LOCUS       DAPOAV010000001       128710 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.001, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000001 DAPOAV010000000
VERSION     DAPOAV010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 128710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 128710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..128710
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.001"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(430..2844)
                     /locus_tag="RN951_000001"
     CDS             complement(430..2844)
                     /locus_tag="RN951_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX2525071.1"
                     /translation="MIARWFWREWRSPSLLIVWLALSLAVACVLALGNISDRMEKGLS
                     QQSREFMAGDRALRSSREVPQAWLEEAQKRGLKVGKQLTFATMTFAGDTPQLANVKAV
                     DDIYPMYGDLQTNPPGLKPQAGSVLLAPRLMALLNLKTGDTIDVGDATLRIAGEVIQE
                     PDSGFNPFQMAPRLMMNLADVDKTGAVQPGSRVTWRYKFGGNENQLDGYEKWLLPQLK
                     PEQRWYGLEQDEGALGRSMERSQQFLLLSALLTLLLAVAAVAVAMNHYCRSCYDLVAI
                     LKTLGAGRAQLRKLIVGQWLMVLTLSAVTGGAIGLLFENVLMVLLKPVLPAALPPASL
                     WPWLWALGTMTVISLLVGLRPYRLLLATQPLRVLRNDVVANVWPLKFYLPIVSVVVVL
                     LLAGLMGGSMLLWAVLAGAVVLALLCGVLGWMLLNVLRRMTLKSLPLRLAVSRLLRQP
                     WSTLSQLSAFSLSFMLLALLLVLRGDLLDRWQQQLPPESPNYFLINIATEQVAPLKAF
                     LAEHQIVPESFYPVVRARLTAINDKPTEGNEDEALNRELNLTWQNTRPDHNPIVAGNW
                     PPKADEVSMEEGLAKRLNVALGDTVTFMGDTQEFRAKVTSLRKVDWESLRPNFYFIFP
                     EGALDGQPQSWLTSFRWENGNGMLTQLNRQFPTISLLDIGAILKQVGQVLEQVSRALE
                     VMVVLVTACGMLLLLAQVQVGMRQRHQELVVWRTLGAGKKLLRTTLWCEFAMLGFVSG
                     LVAAIGAETALAVLQAKVFDFPWEPDWRLWIVLPCSGALLLSLFGGWLGARLVKGKAL
                     FRQFAG"
     gene            complement(2841..3527)
                     /locus_tag="RN951_000002"
     CDS             complement(2841..3527)
                     /locus_tag="RN951_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX2525072.1"
                     /translation="MPAENIVEVHHLKKSVGQGEHELSILTGVELVVKRGETIALVGE
                     SGSGKSTLLAILAGLDDGSSGEVSLVGQPLHNMDEEARAKLRAKHVGFVFQSFMLIPT
                     LNALENVELPALLRGESSAESRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARA
                     FNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLIMVTHDLQLAARCDRCLR
                     LVNGQLQEEA"
     gene            3498..4121
                     /gene="tesA"
                     /locus_tag="RN951_000003"
     CDS             3498..4121
                     /gene="tesA"
                     /locus_tag="RN951_000003"
                     /EC_number="3.1.1.5"
                     /EC_number="3.1.2.14"
                     /EC_number="3.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional acyl-CoA thioesterase I/protease
                     I/lysophospholipase L1"
                     /protein_id="HDX2525073.1"
                     /translation="MNFNNVFRWHLPFLFLVLLTFRAAAADTLLILGDSLSAGYRMSA
                     SAAWPALLNDKWQSKTSVVNASISGDTSQQGLARLPALLKQHQPRWVLVELGGNDGLR
                     GFQPQQTEQTLRQILQDVKAANAEPLLMQIRLPANYGRRYNEAFSAIYPKLAKEFDVP
                     LLPFFMEEVYLKPQWMQDDGIHPNRDAQPFIADWMAKQLQPLVNHDS"
     gene            4111..4920
                     /gene="ybbO"
                     /locus_tag="RN951_000004"
     CDS             4111..4920
                     /gene="ybbO"
                     /locus_tag="RN951_000004"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(+)-dependent aldehyde reductase"
                     /protein_id="HDX2525074.1"
                     /translation="MTHKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLA
                     GCRKPDDVERMNSMGFTGVLIDLDSPESVDRAADEVIALTDNCLYGIFNNAGFGMYGP
                     LSTISRAQMEQQFSANFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYA
                     ASKYALEAWSDALRMELRHSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARF
                     TLGPEAVVDKVRHAFISEKPKMRYPVTLVTWAVMVLKRLLPGRVMDKILQG"
     gene            4981..5835
                     /gene="cnoX"
                     /locus_tag="RN951_000005"
     CDS             4981..5835
                     /gene="cnoX"
                     /locus_tag="RN951_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415025.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperedoxin"
                     /protein_id="HDX2525075.1"
                     /translation="MSVENIVNINESNLQQVLEQSMTTPVLFYFWSERSQHCLQLTPI
                     LESLAAQYNGQFILAKLDCDAEQMIAAQFGLRAIPTVYLFQNGQPVDGFQGPQPEEAI
                     RALLDKVLPREEELKAQQAMQLMQESNYTDALPLLKDAWQLSNQNGEIGLLLAETLIA
                     LNRSEDAEAVLKTIPLQDQDTRYQGLVAQIELLKQAADTPEIQQLQQQVAENPEDAAL
                     ATQLALQLHQVGRNEEALELLFGHLRKDLTAADGQTRKTFQEILAALGTGDALASKYR
                     RQLYALLY"
     gene            complement(5898..6677)
                     /gene="fetB"
                     /locus_tag="RN951_000006"
     CDS             complement(5898..6677)
                     /gene="fetB"
                     /locus_tag="RN951_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308581.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron export ABC transporter permease subunit
                     FetB"
                     /protein_id="HDX2525076.1"
                     /translation="MNSHNITNESLALALMLVVVAILISHKEKLALEKDILWSVGRAI
                     IQLIIVGYVLKYIFSVDDASLTLLMVLFICFNAAWNAQKRSKYIAKAFISSFIAITVG
                     AGITLAVLILSGSIEFIPMQVIPIAGMIAGNAMVAVGLCYNNLGQRVISEQQQIQEKL
                     SLGATPKQASAILIRDSIRAALIPTVDSAKTVGLVSLPGMMSGLIFAGIDPVKAIKYQ
                     IMVTFMLLSTASLSTIIACYLTYRKFYNSRHQLVVTQLKKK"
     gene            complement(6664..7341)
                     /gene="fetA"
                     /locus_tag="RN951_000007"
     CDS             complement(6664..7341)
                     /gene="fetA"
                     /locus_tag="RN951_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter ATP-binding protein FetA"
                     /protein_id="HDX2525077.1"
                     /translation="MQENSPLLQLQNVGYLAGDAKILNNINFSLRAGEFKLITGPSGC
                     GKSTLLKIVASLISPTSGTLLFEGEDVSTLKPEIYRQQVSYCAQTPTLFGDTVYDNLI
                     FPWQIRNRQPDPAIFLDFLERFALPDSILTKNIAELSGGEKQRISLIRNLQFMPKVLL
                     LDEITSALDESNKHNVNEMIHRYVREQNIAVLWVTHDKDEINHADKVITLQPHAGEMQ
                     EARYELA"
     gene            7487..8404
                     /locus_tag="RN951_000008"
     CDS             7487..8404
                     /locus_tag="RN951_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HDX2525078.1"
                     /translation="MLIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPG
                     LSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVS
                     NLELAIINLTMTNIRTVLGSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIR
                     DVRPPAELISSMNAQMKAERTKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSA
                     FLQAEARERSAEAEARATKMVSEAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVM
                     MPLEASSLMGSIAGIAELVKDSANKRTQP"
     gene            8401..8859
                     /locus_tag="RN951_000009"
     CDS             8401..8859
                     /locus_tag="RN951_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415021.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HDX2525079.1"
                     /translation="MMELMVVHPHIFWLSLGGLLLAAEMLGGNGYLLWSGVAAVITGL
                     VVWLVPLGWEWQGVMFAILTLLAAWLWWKWLSRRVREQKHSDSHLNQRGQQLIGRRFV
                     LESPLVNGRGHMRVGDSSWPVSASEDLGAGTHVEVIAIEGITLHIRAVSS"
     gene            complement(8860..9267)
                     /gene="cueR"
                     /locus_tag="RN951_000010"
     CDS             complement(8860..9267)
                     /gene="cueR"
                     /locus_tag="RN951_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(I)-responsive transcriptional regulator"
                     /protein_id="HDX2525080.1"
                     /translation="MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHL
                     NELTLLRQARQVGFNLEESGELVNLFNDPQRHSADVKRRTLEKVAEIERHIEELQSMR
                     DQLLALANACPGDDSADCPIIENLSGCCHHRAG"
     gene            complement(9392..10684)
                     /locus_tag="RN951_000011"
     CDS             complement(9392..10684)
                     /locus_tag="RN951_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDX2525081.1"
                     /translation="MMNTEGNNGNKPLGLWNVVSIGIGAMVGAGIFALLGQAALLMEA
                     STWVAFAFGGIVAMFSGYAYARLGASYPSNGGIIDFFRRGLGNGVFSLALSLLYLLTL
                     AVSIAMVARAFGAYAVQFLHEGSQEEHLILLYALGIIAVMTLFNSLSNHAVGRLEVIL
                     VGIKMMILLLLIIAGVWSLQPAHISVSAPPSSGAFFSCIGITFLAYAGFGMMANAADK
                     VKDPQVIMPRAFLVAIGVTTLLYISLALVLLSDVSALELEKYADTAVAQAASPLLGHV
                     GYVIVVIGALLATASAINANLFAVFNIMDNMGSERELPKLMNKSLWRQSTWGNIIVVV
                     LIMLMTAALNLGSLASVASATFLICYLAVFVVAIRLRHDIHASLPILIVGTLVMLLVI
                     VGFIYSLWSQGSRALIWIIGSLLLSLIVAMVMKRNKTV"
     gene            complement(10687..11619)
                     /gene="glsA"
                     /locus_tag="RN951_000012"
     CDS             complement(10687..11619)
                     /gene="glsA"
                     /locus_tag="RN951_000012"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HDX2525082.1"
                     /translation="MLDANKLQQAVDQAYTQFHSLNGGQNADYIPFLANVPGQLAAVA
                     IVTCDGNVYSAGDSDYRFALESISKVCTLALALEDVGPQAVQDKIGADPTGLPFNSVI
                     ALELHGGKPLSPLVNAGAIATTSLINAENVEQRWQRILHIQQQLAGEQVALSDEVNQS
                     EQTTNFHNRAIAWLLYSAGYLYCDAMEACDVYTRQCSTLLNTIELATLGATLAAGGVN
                     PLTHKRVLQADNVPYILAEMMMEGLYGRSGDWAYRVGLPGKSGVGGGILAVVPGVMGI
                     AAFSPPLDEDGNSVRGQKMVASVAKQLGYNVFKG"
     gene            11881..14385
                     /gene="copA"
                     /locus_tag="RN951_000013"
     CDS             11881..14385
                     /gene="copA"
                     /locus_tag="RN951_000013"
                     /EC_number="7.2.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-exporting P-type ATPase CopA"
                     /protein_id="HDX2525083.1"
                     /translation="MSQTIDLTLDGLSCGHCVKRVKESLEQRPDVEQADVSITEAHVT
                     GTASAEQLIETIKQAGYDASVSHPKAKPLAESSIPSEALTAVSEALPAATADDDDSQQ
                     LLLSGMSCASCVTRVQNALQSVPGVTQARVNLAERTALVMGSASPQDLVQAVEKAGYG
                     AEAIEDDAKRRERQQETAVATMKRFRWQAIVALAVGIPVMVWGMIGDNMMVTADNRSL
                     WLVIGLITLAVMVFAGGHFYRSAWKSLLNGAATMDTLVALGTGVAWLYSMSVNLWPQW
                     FPMEARHLYYEASAMIIGLINLGHMLEARARQRSSKALEKLLDLTPPTARLVTDEGEK
                     SVPLAEVQPGMLLRLTTGDRVPVDGEITQGEAWLDEAMLTGEPIPQQKGEGDSVHAGT
                     VVQDGSVLFRASAVGSHTTLSRIIRMVRQAQSSKPEIGQLADKISAVFVPVVVVIALV
                     SAAIWYFFGPAPQIVYTLVIATTVLIIACPCALGLATPMSIISGVGRAAEFGVLVRDA
                     DALQRASTLDTVVFDKTGTLTEGKPQVVAVKTFADVDEAQALRLAAALEQGSSHPLAR
                     AILDKAGDMQLPQVNGFRTLRGLGVSGEAEGHALLLGNQALLNEQQVGTKAIEAEITA
                     QASQGATPVLLAVDGKAVALLAVRDPLRSDSVAALQRLHKAGYRLVMLTGDNPTTANA
                     IAKEAGIDEVIAGVLPDGKAEAIKHLQSEGRQVAMVGDGINDAPALAQADVGIAMGGG
                     SDVAIETAAITLMRHSLMGVADALAISRATLHNMKQNLLGAFIYNSIGIPVAAGILWP
                     FTGTLLNPVVAGAAMALSSITVVSNANRLLRFKPKE"
     gene            complement(14600..14941)
                     /locus_tag="RN951_000014"
     CDS             complement(14600..14941)
                     /locus_tag="RN951_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415016.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HigA family addiction module antidote protein"
                     /protein_id="HDX2525084.1"
                     /translation="MKQATRKPTTPGDILLYEYLEPLDLKINELAELLHVHRNSVSAL
                     INNNRKLTTEMAFRLAKVFDTTVDFWLNLQAAVDLWEVENNMRTQEELGRIETVAEYL
                     ARREERAKKVA"
     gene            15079..15873
                     /locus_tag="RN951_000015"
     CDS             15079..15873
                     /locus_tag="RN951_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraB/GumN family protein"
                     /protein_id="HDX2525085.1"
                     /translation="MDLLYRVKTLWAALRGNHYTWPAIDITLPGNRHFHLIGSIHMGS
                     HDMAPLPTRLLKKLKNADALIVEADVSTSDTPFANLPACEALEERISEEQLQNLQHIS
                     QEMGISPSLFSTQPLWQIAMVLQATQAQKLGLRAEYGIDYQLLQAAKQQHKPVIELEG
                     AENQIAMLLQLPDKGLALLDDTLTHWHTNARLLQQMMSWWLNAPPQNNDITLPNTFSQ
                     SLYDVLMHQRNLAWRDKLRAMPPGRYVVAVGALHLYGEGNLPQMLR"
     gene            16077..16556
                     /gene="ybaK"
                     /locus_tag="RN951_000016"
     CDS             16077..16556
                     /gene="ybaK"
                     /locus_tag="RN951_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK"
                     /protein_id="HDX2525086.1"
                     /translation="MTPAVKLLEKNKISFQIHTYEHDPAETNFGDEVVKKLGLNPDQV
                     YKTLLVAVNGDMKHLAVAVTPVAGQLDLKKVAKALGAKKVEMADPMVAQRSTGYLVGG
                     ISPLGQKKRLPTIIDAPAQEFATIYVSGGKRGLDIELAAGDLAKILDAKFADIARRD"
     gene            complement(16593..18245)
                     /gene="ushA"
                     /locus_tag="RN951_000017"
     CDS             complement(16593..18245)
                     /gene="ushA"
                     /locus_tag="RN951_000017"
                     /EC_number="3.1.3.5"
                     /EC_number="3.6.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-sugar
                     hydrolase/5'-nucleotidase"
                     /protein_id="HDX2525087.1"
                     /translation="MKLLQRGVALALLTTFTLASETALAYEQDKTYKITVLHTNDHHG
                     HFWRNEYGEYGLAAQKTLVDGIRKEVAAEGGSVLLLSGGDINTGVPESDLQDAEPDFR
                     GMNLVGYDAMAIGNHEFDNPLTVLRQQEKWAKFPLLSANIYQKSTGERLFKPWALFKR
                     QDLKIAVIGLTTDDTAKIGNPEYFTDIEFRKPADEAKLVIQELQQTEKPDIIIAATHM
                     GHYDNGEHGSNAPGDVEMARALPAGSLAMIVGGHSQDPVCMAAENKKQVDYVPGTPCK
                     PDQQNGIWIVQAHEWGKYVGRADFEFRNGEMKMVNYQLIPVNLKKKVTWEDGKSERVL
                     YTPEIAENQQMISLLSPFQNKGKAQLEVKIGETNGRLEGDRDKVRFVQTNMGRLILAA
                     QMDRTGADFAVMSGGGIRDSIEVGDISYKNVLKVQPFGNVVVYADMTGKEVIDYLTAV
                     AQMKPDSGAYPQFANVSFVAKDGKLNDLKIKGEPVDPAKTYRMATLNFNATGGDGYPR
                     LDNKPGYVNTGFIDAEVLKAYIQKSSPLDVSVYEPKGEVSWQ"
     gene            18463..19683
                     /gene="fsr"
                     /locus_tag="RN951_000018"
     CDS             18463..19683
                     /gene="fsr"
                     /locus_tag="RN951_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fosmidomycin MFS transporter"
                     /protein_id="HDX2525088.1"
                     /translation="MAMSEQPQPVAGAAASTTKARTSFGILGAISLSHLLNDMIQSLI
                     LAIYPLLQSEFSLTFMQIGMITLTFQLASSLLQPVVGYWTDKYPMPWSLPIGMCFTLS
                     GLVLLALAGSFGAVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFG
                     SSLGPLLAAVIIAPYGKGNVAWFVLAALLAIVVLAQISRWYSAQHRMNKGKPKATIIN
                     PLPRNKVVLAVSILLILIFSKYFYMASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAV
                     AAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLILPYASLHWTGVLTVIIGFILASAFS
                     AILVYAQELLPGRIGMVSGLFFGFAFGMGGLGAAVLGLIADHTSIELVYKICAFLPLL
                     GMLTIFLPDNRHKD"
     gene            19921..21597
                     /locus_tag="RN951_000019"
     CDS             19921..21597
                     /locus_tag="RN951_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Kef family K(+) transporter"
                     /protein_id="HDX2525089.1"
                     /translation="MHHATPLITTIVGGLVLAFILGMLANKLRISPLVGYLLAGVLAG
                     PFTPGFVADTKLAPELAELGVILLMFGVGLHFSLKDLMAVKAIAIPGAIAQIAVATLL
                     GMALSAVLGWSLMTGIVFGLCLSTASTVVLLRALEERQLIDSQRGQIAIGWLIVEDLV
                     MVLTLVLLPAVAGMMEQGDVGFATLAVDMGITIGKVIAFIAIMMLVGRRLVPWIMARS
                     AATGSRELFTLSVLALALGVAFGAVELFDVSFALGAFFAGMVLNESELSHRAAHDTLP
                     LRDAFAVLFFVSVGMLFDPLILIQQPLAVLATLAIILFGKSLAAFFLVRLFGHSQRTA
                     LTIAASLAQIGEFAFILAGLGMALNLLPQAGQNLVLAGAILSIMLNPVLFALLEKYLA
                     KTETLEEQTLEEAIEEEKQIPVDICNHALLVGYGRVGSLLGEKLLASDIPLVVIETSR
                     TRVDELRERGVRAVLGNAANEEIMQLAHLECAKWLILTIPNGYEAGEIVASARAKNPD
                     IEIIARAHYDDEVAYITERGANQVVMGEREIARTMLELLETPPAGEVVTG"
     gene            complement(21730..23034)
                     /gene="gsk"
                     /locus_tag="RN951_000020"
     CDS             complement(21730..23034)
                     /gene="gsk"
                     /locus_tag="RN951_000020"
                     /EC_number="2.7.1.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/guanosine kinase"
                     /protein_id="HDX2525090.1"
                     /translation="MKFPGKRKSKHYFPVNARDPLLQQFQPENETSAAWVVGIDQTLV
                     DIEAKVDDEFIERYGLSAGHSLVIEDDVAEALYQELKQKNLITHQFAGGTIGNTMHNY
                     SVLADDRSVLLGVMCSNIEIGSYAYRYLCNTSSRTDLNYLQGVDGPIGRCFTLIGESG
                     ERTFAISPGHMNQLRAESIPEDVIAGASALVLTSYLVRCKPGEPMPEATMKAIEYAKK
                     YNVPVVLTLGTKFVIAENPQWWQQFLKDHVSILAMNEDEAEALTGESDPLLASDKALD
                     WVDLVLCTAGPIGLYMAGFTEDEAKRKTQHPLLPGAIAEFNQYEFSRAMRHKDCQNPL
                     RVYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANSYHRSNVPNSSKHKFTWLTYS
                     SLAQVCKYANRVSYQVLNQHSPRLTRGLPEREDSLEESYWDR"
     gene            23186..24145
                     /gene="aes"
                     /locus_tag="RN951_000021"
     CDS             23186..24145
                     /gene="aes"
                     /locus_tag="RN951_000021"
                     /EC_number="3.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl esterase"
                     /protein_id="HDX2525091.1"
                     /translation="MKPENKLPVLDLISAEMKTVVNTLQPDLPPWPATGTIAEQRQYY
                     TLERRFWNAGAPEMATRAYMVPTKYGQVETRLFCPQPDSPATLFYLHGGGFILGNLDT
                     HDRIMRLLASYSQCTVIGIDYTLSPEARFPQAIEEIVAACCYFHQQAEDYQINMSRIG
                     FAGDSAGAMLALASALWLRDKQIDCGKVAGVLLWYGLYGLRDSVTRRLLGGVWDGLTQ
                     QDLQMYEEAYLSNDADRESPYYCLFNNDLTREVPPCFIAGAEFDPLLDDSRLLYQTLA
                     AHQQPCEFKLYPGTLHAFLHYSRMMKTADEALRDGAQFFTAQL"
     gene            complement(24142..25104)
                     /gene="hemH"
                     /locus_tag="RN951_000022"
     CDS             complement(24142..25104)
                     /gene="hemH"
                     /locus_tag="RN951_000022"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HDX2525092.1"
                     /translation="MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTSRLL
                     WWPLLRGVILPLRSPRVAKLYASVWMEGGSPLMVYSRQQQQALAQRLPEMPVALGMSY
                     GSPSLESAVDELLAEHVDHIVVLPLYPQFSCSTVGAVWDELARILARKRSIPGISFIR
                     DYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRYADEGDDYPQRCRTTTREL
                     ASALGMAPEKVMMTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLET
                     LEEIAEQNREVFLGAGGKKYEYIPALNATPEHIEMMANLVAAYR"
     gene            complement(25340..25984)
                     /gene="adk"
                     /locus_tag="RN951_000023"
     CDS             complement(25340..25984)
                     /gene="adk"
                     /locus_tag="RN951_000023"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007706188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HDX2525093.1"
                     /translation="MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSE
                     LGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGIN
                     VDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQ
                     EETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG"
     gene            complement(26165..28039)
                     /gene="htpG"
                     /locus_tag="RN951_000024"
     CDS             complement(26165..28039)
                     /gene="htpG"
                     /locus_tag="RN951_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003903109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HDX2525094.1"
                     /translation="MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAAD
                     KLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGT
                     KSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEG
                     EYTVADITKEDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDG
                     ETVISWEKINKAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTS
                     LLYIPSQAPWDMWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNV
                     SREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFAN
                     QEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELL
                     RKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKAL
                     TPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEVKY
                     IFELNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLVS
                     "
     gene            complement(28149..28754)
                     /gene="recR"
                     /locus_tag="RN951_000025"
     CDS             complement(28149..28754)
                     /gene="recR"
                     /locus_tag="RN951_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HDX2525095.1"
                     /translation="MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLA
                     QALTRAMSEIGHCADCRTFTEQEVCNICSNPRRQENGQICVVESPADIYAIEQTGQFS
                     GRYFVLMGHLSPLDGIGPDDIGLDRLEQRLAEEKITEVILATNPTVEGEATANYIAEL
                     CAQYDVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIRF"
     gene            complement(28754..29083)
                     /locus_tag="RN951_000026"
     CDS             complement(28754..29083)
                     /locus_tag="RN951_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001364632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HDX2525096.1"
                     /translation="MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKV
                     TINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLP
                     PGFKMPF"
     gene            complement(29136..31067)
                     /gene="dnaX"
                     /locus_tag="RN951_000027"
     CDS             complement(29136..31067)
                     /gene="dnaX"
                     /locus_tag="RN951_000027"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HDX2525097.1"
                     /translation="MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFS
                     GTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKVE
                     DTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ
                     KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDAL
                     SLTDQAIASGDGQVSTQAVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGI
                     EWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTIPPTDIQLYYQTLLI
                     GRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQSFAPVAPTAVMTPTQVPPQ
                     PQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATKAKKSEPAAATRARPVNNAALERL
                     ASVTDRVQARPVPSALEKAPAKKEAYRWKATTPVMQQKEVVATPKALKKALEHEKTPE
                     LAAKLAAEAIERDPWAAQVSQLSLPKLVEQVALNAWKEESDNAVCLHLRSSQRHLNNR
                     GAQQKLAEALSMLKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNI
                     QTLRRFFDAELDEESIRPI"
     misc_feature    complement(29739..29803)
                     /gene="dnaX"
                     /locus_tag="RN951_000027"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00382"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="DnaX frameshifting element; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00382"
     gene            complement(31196..31747)
                     /gene="apt"
                     /locus_tag="RN951_000028"
     CDS             complement(31196..31747)
                     /gene="apt"
                     /locus_tag="RN951_000028"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HDX2525098.1"
                     /translation="MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALS
                     IDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDL
                     EYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFD
                     LGGEQRLEKQGITSYSLVPFPGH"
     gene            complement(31900..32277)
                     /locus_tag="RN951_000029"
     CDS             complement(31900..32277)
                     /locus_tag="RN951_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF454 family protein"
                     /protein_id="HDX2525099.1"
                     /translation="MQRIILIIIGWLAVVLGTLGVVLPVLPTTPFILLAAWCFARSSP
                     RFHAWLLYRSWFGSYLRFWQKHHAMPRGVKPRAILLILLTFAISLWFVQMPWVRIMLL
                     VILACLLFYMWRIPVIDEKQEKH"
     gene            32347..32874
                     /gene="priC"
                     /locus_tag="RN951_000030"
     CDS             32347..32874
                     /gene="priC"
                     /locus_tag="RN951_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N''"
                     /protein_id="HDX2525100.1"
                     /translation="MKTALLLEKLEGQLATLRQRCAPVSQFATLSARFDRHLFQTRAT
                     TLQACLDEAGDNLAALRHAVEQQQLPQVAWLAEHLAAQLEAIAREASAWSLREWDSAP
                     PKIARWQRKRIQHQDFERRLREMVAERRAHLARVTDLVEQQTLHREVEAYEARLARCR
                     HALEKIENRLARLTR"
     gene            32888..33049
                     /gene="rsmS"
                     /locus_tag="RN951_000031"
     CDS             32888..33049
                     /gene="rsmS"
                     /locus_tag="RN951_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pleiotropic regulatory protein RsmS"
                     /protein_id="HDX2525101.1"
                     /translation="MSLENAPDDVKLAVDLIVLLEENQIPASTVLRALDIVKRDYEKK
                     LTRDDEAEK"
     gene            complement(33261..36623)
                     /gene="mscK"
                     /locus_tag="RN951_000032"
     CDS             complement(33261..36623)
                     /gene="mscK"
                     /locus_tag="RN951_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel MscK"
                     /protein_id="HDX2525102.1"
                     /translation="MTMFQYYKRSRHFVFSAFIAFVFVLLCQNTAFARASSNGDLPTK
                     ADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDKIDRIKEETVQLRQKVAEAPEKM
                     RQATAALTALSDVDNDEETRKILSTLSLRQLETRVAQALDDLQNAQNDLASYNSQLVS
                     LQTQPERVQNAMYNASQQLQQIRSRLDGTDVGETALRPSQKVLMQAQQALLNAEIDQQ
                     RKSLEGNTVLQDTLQKQRDYVTANSARLEHQLQLLQEAVNSKRLTLTEKTAQEAVSPD
                     EAARIQANPLVKQELEINQQLSQRLITATENGNQLMQQNIKVKNWLERALQSERNIKE
                     QIAVLKGSLLLSRILYQQQQTLPSADELENMTNRIADLRLEQFEVNQQRDALFQSDAF
                     VNKLEEGHTNEVNSEVHDALLQVVDMRRELLDQLNKQLGNQLMMAINLQINQQQLMSV
                     SKNLKSILTQQIFWVNSNRPMDWDWIKAFPQSLKDEFKSMKITVNWQKAWPAVFIAFL
                     AGLPLLLIAGLIHWRLGWLKAYQQKLASAVGSLRNDSQLNTPKAILIDLIRALPVCLI
                     ILAVGLILLTMQLNISELLWSFSKKLAIFWLVFGLCWKVLEKNGVAVRHFGMPEQQTS
                     HWRRQIVRISLALLPIHFWSVVAELSPLHLMDDVLGQAMIFFNLLLIAFLVWPMCRES
                     WRDKESHTMRLVTITVLSIIPIALMVLTATGYFYTTLRLAGRWIETVYLVIIWNLLYQ
                     TVLRGLSVAARRIAWRRALARRQNLVKEGAEGAEPPEEPTIALEQVNQQTLRITMLLM
                     FALFGVMFWAIWSDLITVFSYLDSITLWHYNGTEAGAAVVKNVTMGSLLFAIIASMVA
                     WALIRNLPGLLEVLVLSRLNMRQGASYAITTILNYIIIAVGAMTVFGSLGVSWDKLQW
                     LAAALSVGLGFGLQEIFGNFVSGLIILFERPVRIGDTVTIGSFSGTVSKIRIRATTIT
                     DFDRKEVIIPNKAFVTERLINWSLTDTTTRLVIRLGVAYGSDLEKVRKVLLKAATEHP
                     RVMHEPMPEVFFTAFGASTLDHELRLYVRELRDRSRTVDELNRTIDQLCRENDINIAF
                     NQLEVHLHNEKGDEVTEVKRDYKGDDPTPAVG"
     gene            complement(36751..37398)
                     /gene="acrR"
                     /locus_tag="RN951_000033"
     CDS             complement(36751..37398)
                     /gene="acrR"
                     /locus_tag="RN951_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor AcrR"
                     /protein_id="HDX2525103.1"
                     /translation="MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVT
                     RGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVT
                     EERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMT
                     RRAAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE"
     gene            37540..38733
                     /gene="acrA"
                     /locus_tag="RN951_000034"
     CDS             37540..38733
                     /gene="acrA"
                     /locus_tag="RN951_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrA"
                     /protein_id="HDX2525104.1"
                     /translation="MNKNRGFTPLAVVLMLSGSLALTGCDDKQAQQGGQQMPAVGVVT
                     VKTEPLQITTELPGRTSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQ
                     ATYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAA
                     KAAVETARINLAYTKVTSPISGRIGKSNVTEGALVQNGQATALATVQQLDPIYVDVTQ
                     SSNDFLRLKQELANGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVDQTTGSITL
                     RAIFPNPDHTLLPGMFVRARLEEGLNPNAILVPQQGVTRTPRGDATVLVVGADDKVET
                     RPIVASQAIGDKWLVTEGLKAGDRVVISGLQKVRPGVQVKAQEVTADNNQQAASGAQP
                     EQSKS"
     gene            38756..41905
                     /locus_tag="RN951_000035"
     CDS             38756..41905
                     /locus_tag="RN951_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HDX2525105.1"
                     /translation="MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVT
                     ISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADI
                     AQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA
                     NMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQ
                     LGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYD
                     IIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVK
                     ISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLS
                     AVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEG
                     KKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPD
                     EDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNT
                     GIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDF
                     ELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALG
                     VSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQM
                     VPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVG
                     YDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALL
                     AATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRL
                     RPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVR
                     RRFSRKNEDIEHSHTVDHH"
     gene            42451..42825
                     /gene="tomB"
                     /locus_tag="RN951_000036"
     CDS             42451..42825
                     /gene="tomB"
                     /locus_tag="RN951_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hha toxicity modulator TomB"
                     /protein_id="HDX2525106.1"
                     /translation="MDEYSPKRHDIAQLKFLCETLYHDCLANLEESNHGWVNDPTSAI
                     NLQLNELIEHIATFALNYKIKYNEDNKLIEQIDEYLDDTFMLFSSYGINMQDLQKWRK
                     SGNRLFRCFVNATKENPASLSC"
     gene            42851..43069
                     /gene="hha"
                     /locus_tag="RN951_000037"
     CDS             42851..43069
                     /gene="hha"
                     /locus_tag="RN951_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="HDX2525107.1"
                     /translation="MSEKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFY
                     SAADHRLAELTMNKLYDKIPSSVWKFIR"
     gene            43241..43792
                     /gene="maa"
                     /locus_tag="RN951_000038"
     CDS             43241..43792
                     /gene="maa"
                     /locus_tag="RN951_000038"
                     /EC_number="2.3.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose O-acetyltransferase"
                     /protein_id="HDX2525108.1"
                     /translation="MSTEKEKMIAGELYRSADETLSRDRLRARQLIHRYNHSLAEEHT
                     LRQQILADLFGQVTEAYIEPTFRCDYGYNIFLGNNFFANFDCVMLDVCPIRIGDNCML
                     APGVHIYTATHPIDPVARNSGAELGKPVTIGNNVWIGGRAVINPGVTIGDNVVVASGA
                     VVTKDVPDNVVVGGNPARIIKKL"
     gene            43908..44378
                     /locus_tag="RN951_000039"
     CDS             43908..44378
                     /locus_tag="RN951_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308538.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaC family protein"
                     /protein_id="HDX2525109.1"
                     /translation="MTEIQRLLTETIESLNTREKRDNKPRFSISFIRKHPGLFIGMYV
                     AFFATLAVMLQSETLSGSVWLLVVLFILLNGFFFFDVYPRYRYEDIDVLDFRVCYNGE
                     WYNTRFVPAALVEAILNSPRVADVHKEQLQKMIVRKGELSFYDIFTLARAESTS"
     gene            44542..46092
                     /gene="pdeB"
                     /locus_tag="RN951_000040"
     CDS             44542..46092
                     /gene="pdeB"
                     /locus_tag="RN951_000040"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414990.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase
                     PdeB"
                     /protein_id="HDX2525110.1"
                     /translation="MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTY
                     SSRVAIRANKVATQGKDALQELERWQGAACSEAHLMEMRRVSYSYRYIQEVAYIDNNV
                     PQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPAS
                     FIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILP
                     LPEMNISIITWASTKMLQKGWHRQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQ
                     DAIENRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSPDSFIPLAQQTGLSEPL
                     TLLIIRSVFEDMGDWLRQHPQQHISINLESPVLTSEKIPQLLRDMINHYQVNPRQIAL
                     ELTEREFADPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVD
                     ALEYKNVTPHIIEMAKTLKLKMVAEGIETSKQEEWLRQHGVHYGQGWLYSKALPKEDF
                     LRWAEQHL"
     gene            complement(46134..46487)
                     /locus_tag="RN951_000041"
     CDS             complement(46134..46487)
                     /locus_tag="RN951_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1428 domain-containing protein"
                     /protein_id="HDX2525111.1"
                     /translation="MKYVDGFVVAVPADKKDAYREMAAKAAPLFKEFGALRIVECWAS
                     DVPDGKVTDFRMAVKAEENEEVVFSWIEYPSKEVRDAANQKMMSDPRMKEFGESMPFD
                     GKRMIYGGFESIIDE"
     gene            complement(46607..46703)
                     /gene="ffs"
                     /locus_tag="RN951_000042"
     ncRNA           complement(46607..46703)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="RN951_000042"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            46866..47177
                     /locus_tag="RN951_000043"
     CDS             46866..47177
                     /locus_tag="RN951_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706349.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MGMT family protein"
                     /protein_id="HDX2525112.1"
                     /translation="MEKEDSFPQRVWQIVAAIPEGYVTTYGDVAKLAGSPRAARQVGG
                     VLKRLPEGSTLPWHRVVNRHGTISLTGPDLQRQRQALLAEGVMVSGSGQIDLQRYRWN
                     Y"
     gene            complement(47208..47780)
                     /locus_tag="RN951_000044"
     CDS             complement(47208..47780)
                     /locus_tag="RN951_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaY family lipoprotein"
                     /protein_id="HDX2525113.1"
                     /translation="MKLVHMASGLAVAIALAACADKSADIQTPAPAANTSISATQQPA
                     IQQPNVSGTVWIRQKVALPPDAVLTVTLSDASLADAPSKVLAQKAVRTEGKQSPFSFV
                     LPFNPADVQPNARILLSAAITVNDKLVFITDTVQPVINQGGTKADLTLVPVQQTAVPV
                     QASGGATTTVPSTSPTQVNPSSAVPAPTQY"
     gene            47998..48858
                     /gene="tesB"
                     /locus_tag="RN951_000045"
     CDS             47998..48858
                     /gene="tesB"
                     /locus_tag="RN951_000045"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase II"
                     /protein_id="HDX2525114.1"
                     /translation="MSQALKNLLTLLNLEKIEEGLFRGQSEDLGLRQVFGGQVVGQAL
                     YAAKETVPEERLVHSFHSYFLRPGDSKKPIIYDVETLRDGNSFSARRVAAIQNGKPIF
                     YMTASFQAPEAGFEHQKTMPSAPAPDGLPSETQITQSLAHLLPPVLKDKFICDRPLEV
                     RPVEFHNPLKGHVAEPHRQVWIRANGSVPDDLRVHQYLLGYASDLNFLPVALQPHGIG
                     FLEPGIQIATIDHSMWFHRPFNLNEWLLYSVESTSASSARGFVRGEFYTQDGVLVAST
                     VQEGVMRNHN"
     gene            complement(48907..50193)
                     /gene="amtB"
                     /locus_tag="RN951_000046"
     CDS             complement(48907..50193)
                     /gene="amtB"
                     /locus_tag="RN951_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter AmtB"
                     /protein_id="HDX2525115.1"
                     /translation="MKIATIKTGLASLAMLPGLVMAAPAVADKADNAFMMICTALVLF
                     MTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINW
                     LMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTL
                     SYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIGKRVGFGKEAFKPH
                     NLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRG
                     KPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLKRLLRVDDPC
                     DVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVA
                     FIGYKLADLTVGLRVPEEQEREGLDVNSHGENAYNA"
     gene            complement(50223..50561)
                     /gene="glnK"
                     /locus_tag="RN951_000047"
     CDS             complement(50223..50561)
                     /gene="glnK"
                     /locus_tag="RN951_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HDX2525116.1"
                     /translation="MKLVTVIIKPFKLEDVREALSSIGIQGLTVTEVKGFGRQKGHAE
                     LYRGAEYSVNFLPKVKIDVAIADDQLDEVIDIVSKAAYTGKIGDGKIFVAELQRVIRI
                     RTGEADEAAL"
     gene            complement(50742..52523)
                     /locus_tag="RN951_000048"
     CDS             complement(50742..52523)
                     /locus_tag="RN951_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SmdB family multidrug efflux ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HDX2525117.1"
                     /translation="MRSFSQLWPTLKRLLAYGSPWRKPLGIAVLMMWVAAAAEVSGPL
                     LISYFIDNMVAKNNLPLKVVAGLAAAYVGLQLFAAGLHYAQSLLFNRAAVGVVQQLRT
                     DVMDAALRQPLSEFDTQPVGQVISRVTNDTEVIRDLYVTVVATVLRSAALVGAMLVAM
                     FSLDWRMALVAIMIFPVVLVVMVIYQRYSTPIVRRVRAYLADINDGFNEIINGMSVIQ
                     QFRQQARFGERMGEASRSHYMARMQTLRLDGFLLRPLLSLFSSLILCGLLMLFGFSAS
                     GTIEVGVLYAFISYLGRLNEPLIELTTQQAMLQQAVVAGERVFELMDGPRQQYGNDDR
                     PLQSGTIEVDNVSFAYRDDNLVLKNINLSVPSRNFVALVGHTGSGKSTLASLLMGYYP
                     LTEGEIRLDGRPLSSLSHSALRQGVAMVQQDPVVLADTFLANVTLGRDISEERVWQAL
                     ETVQLAELARSMSDGIYTPLGEQGNNLSVGQKQLLALARVLVETPQILILDEATASID
                     SGTEQAIQHALAAVREHTTLVVIAHRLSTIVDADTILVLHRGQAVEQGTHQQLLAAQG
                     RYWQMYQLQLAGEELAASVREEESLSA"
     gene            complement(52516..54288)
                     /locus_tag="RN951_000049"
     CDS             complement(52516..54288)
                     /locus_tag="RN951_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SmdA family multidrug ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HDX2525118.1"
                     /translation="MRLFAQLSWYFRREWRRYLGAVALLVIIAMLQLVPPKVVGIVVD
                     GVTEQHFTTGQILMWIATMVLIAVVVYLLRYVWRVLLFGASYQLAVELREDYYRQLSR
                     QHPEFYLRHRTGDLMARATNDVDRVVFAAGEGVLTLVDSLVMGCAVLIMMSTQISWQL
                     TLFSLLPMPVMAIMIKRNGDALHERFKLAQAAFSSLNDRTQESLTSIRMIKAFGLEDR
                     QSALFAADAEDTGKKNMRVARIDARFDPTIYIAIGMANLLAIGGGSWMVVQGSLTLGQ
                     LTSFMMYLGLMIWPMLALAWMFNIVERGSAAYSRIRAMLAEAPVVNDGSEPVPEGRGE
                     LDVNIHQFTYPQTDHPALENVNFALKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGD
                     IRFHDIPLTKLQLDSWRSRLAVVSQTPFLFSDTVANNIALGCPNATQQEIEHVARLAS
                     VHDDILRLPQGYDTEVGERGVMLSGGQKQRISIARALLVNAEILILDDALSAVDGRTE
                     HQILHNLRQWGQGRTVIISAHRLSALTEASEIIVMQHGHIAQRGNHDVLAQQSGWYRD
                     MYRYQQLEAALDDAPENREEAVDA"
     gene            complement(54318..54776)
                     /gene="decR"
                     /locus_tag="RN951_000050"
     CDS             complement(54318..54776)
                     /gene="decR"
                     /locus_tag="RN951_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DecR"
                     /protein_id="HDX2525119.1"
                     /translation="MLDKIDRKLLALLQQDCTLSLQALAEAVNLTTTPCWKRLKRLED
                     DGILIGKVALLDPEKIGLGLTAFVLIKTQHHSSEWYCRFVTVVTEMPEVLGFWRMAGE
                     YDYLMRVQVADMKRYDEFYKRLVNSVPGLSDVTSSFAMEQIKYTTSLPIE"
     gene            complement(54929..55747)
                     /gene="cof"
                     /locus_tag="RN951_000051"
     CDS             complement(54929..55747)
                     /gene="cof"
                     /locus_tag="RN951_000051"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414980.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HMP-PP phosphatase"
                     /protein_id="HDX2525120.1"
                     /translation="MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGR
                     HALEMQHILGALSLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASM
                     HIFNDDGWFTGKEIPALLQAFVYSGFRYQIIDVKKMPLGSVTKICFCGDHDDLTRLQI
                     QLYEALGERAHLCFSATDCLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDRE
                     MLVSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDYPHLPYSPE"
     gene            55847..57547
                     /locus_tag="RN951_000052"
     CDS             55847..57547
                     /locus_tag="RN951_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SgrR family transcriptional regulator"
                     /protein_id="HDX2525121.1"
                     /translation="MRLLNRLNQYQRLWQPSAGKPQTVTVSELAERCFCSERHVRTLL
                     RQAQEAGWLEWQAQSGRGKRGQLRFLVTPESLRNAMMEQALETGKQQDVLELAQLAPG
                     ELRTLLQPFMGGQWQNDTPTLRIPYYRPLEPLQPGFLPGRAEQHLAGQIFSGLTRFDN
                     NTQRPIGDLAHHWETSTDGLRWDFYLRSTLHWHNGDAVKASHLHQRLLMLLQLPALDQ
                     LFISVKRIEVTHPQCLTFFLHRPDYWLAHRLASYCSHLAHPQFPLIGTGPFRLTQFTA
                     ELVRLESHDYYHLRHPLLKAVEYWITPPLFEKDLGTSCRHPVQITIGKPEELQRVSQV
                     SSGISLGFCYLTLRKSPRLSLWQARKVISIIHQSGLLQTLEVGENLITASHALLPGWT
                     IPHWQVPDEVKLPKTLTLVYHLPIELHTMAERLQATLAAEGCELTIIFHNAKNWDDTT
                     LQAHADLMMGDRLIGEAPEYTLEQWLRCDPLWPHVFDAPAYAHLQSTLDAVQIMPDEE
                     NRFNALKAVFSQLMTDATLTPLFNYHYRISAPPGVNGVRLTPRGWFEFTEAWLPAPSQ
                     "
     gene            57612..58307
                     /gene="queC"
                     /locus_tag="RN951_000053"
     CDS             57612..58307
                     /gene="queC"
                     /locus_tag="RN951_000053"
                     /EC_number="6.3.4.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="HDX2525122.1"
                     /translation="MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEID
                     VARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNIL
                     FLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPL
                     MWIDKAETWALADYYGKLDLVRNETLTCYNGFKGDGCGHCAACNLRANGLNHYLADKP
                     TVMAAMKQKTGLR"
     gene            complement(58359..58757)
                     /gene="fadM"
                     /locus_tag="RN951_000054"
     CDS             complement(58359..58757)
                     /gene="fadM"
                     /locus_tag="RN951_000054"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain acyl-CoA thioesterase FadM"
                     /protein_id="HDX2525123.1"
                     /translation="MQTQIKVRGYHLDVYQHVNNARYLEFLEEARWDGLENSDSFQWM
                     TAHNIAFVVVNININYRRPAVLSDLLTITSQLQQLNGKSGILSQVITLEPEGQVVADA
                     LITFVCIDLKTQKALALEGELREKLEQMVK"
     gene            complement(58851..59222)
                     /locus_tag="RN951_000055"
     CDS             complement(58851..59222)
                     /locus_tag="RN951_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HDX2525124.1"
                     /translation="MKHGIKALLITLSLACAGMSHSALAAASVAKPTAVETKAEAPAA
                     QSKAAVPAKASDEEGTRVSINNASAEELARAMNGVGLKKAQAIVSYREEYGPFKTVED
                     LKQVPGMGNSLVERNLAVLTL"
     gene            complement(59373..61244)
                     /gene="ppiD"
                     /locus_tag="RN951_000056"
     CDS             complement(59373..61244)
                     /gene="ppiD"
                     /locus_tag="RN951_000056"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDX2525125.1"
                     /translation="MMDSLRTAANSLVLKIIFGIIIVSFILTGVSGYLIGGGNNYAAK
                     VNDQEISRGQFENAFNSERNRMQQQLGDQYSELAANEGYMKTLRQQVLNRLIDEALLD
                     QYARELKLGISDEQVKQAIFATPAFQVDGKFDNSRYNGILNQMGMTADQYAQALRNQL
                     TTQQLINGVAGTDFMLKGETDELAALVAQQRVVREATIDVNALAAKQPVTEQEIASYY
                     EQNKNNFMTPEQFRVSYIKLDAATMQQPVSDADIQSYYDQHQDQFTQPQRTRYSIIQT
                     KTEDEAKAVLDELNKGGDFAALAKEKSADIISARNGGDMGWLEDATIPDELKNAGLKE
                     KGQLSGVIKSSVGFLIVRLDDIQPAKVKSLDEVRDDIAAKVKHEKALDAYYALQQKVS
                     DAASNDTESLAGAEQAAGVKATQTGWFSKDNLPEELNFKPVADAIFNGGLVGENGAPG
                     INSDIITVDGDRAFVLRISEHKPEAVKPLADVQEQVKALVQHNKAEQQAKVDAEKLLV
                     DLKAGKGAEAMQAAGLKFGEPKTLSRSGRDPISQAAFALPLPAKDKPSYGMATDMQGN
                     VVLLALDEVKQGSMPEDQKKAMVQGITQNNAQIVFEALMSNLRKEAKIKIGDALEQQ"
     gene            complement(61436..61708)
                     /gene="hupB"
                     /locus_tag="RN951_000057"
     CDS             complement(61436..61708)
                     /gene="hupB"
                     /locus_tag="RN951_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-beta"
                     /protein_id="HDX2525126.1"
                     /translation="MNKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVAL
                     VGFGTFAVKERAARTGRNPQTGKEITIAAAKVPSFRAGKALKDAVN"
     gene            complement(61917..64271)
                     /gene="lon"
                     /locus_tag="RN951_000058"
     CDS             complement(61917..64271)
                     /gene="lon"
                     /locus_tag="RN951_000058"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001469947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HDX2525127.1"
                     /translation="MNPERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAM
                     DHDKKIMLVAQKEASTDEPGVNDLFTVGTVASILQMLKLPDGTVKVLVEGLQRARISA
                     LSDNGEHFSAKAEYLESPTIDEREQEVLVRTAISQFEGYIKLNKKIPPEVLTSLNSID
                     DPARLADTIAAHMPLKLADKQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVK
                     KQMEKSQREYYLNEQMKAIQKELGEMDDAPDENEALKRKIDAAKMPKEAKEKAEAELQ
                     KLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVKKDLRQAQEILDTDHYGLERVKDRI
                     LEYLAVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIR
                     GHRRTYIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNV
                     AFSDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKRHLLP
                     KQIERNALKKGELTVDDSAIIGIIRYYTREAGVRGLEREISKLCRKAVKQLLLDKSLK
                     HIEINGDNLHDYLGVQRFDYGRADNENRVGQVTGLAWTEVGGDLLTIETACVPGKGKL
                     TYTGSLGEVMQESIQAALTVVRARAEKLGINPDFYEKRDIHVHVPEGATPKDGPSAGI
                     AMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLKEKLLAAHRGGIKTVLIPFEN
                     KRDLEEIPDNVIADLDIHPVKRIEEVLTLALQNEPSGMQVVTAK"
     gene            complement(64459..65733)
                     /gene="clpX"
                     /locus_tag="RN951_000059"
     CDS             complement(64459..65733)
                     /gene="clpX"
                     /locus_tag="RN951_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATP-binding subunit ClpX"
                     /protein_id="HDX2525128.1"
                     /translation="MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLC
                     NDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNG
                     DTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
                     IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGT
                     VAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVISHRVETGSGIGFGATVKA
                     KSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALT
                     KQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMED
                     VEKVVIDESVIDGQSKPLLIYGKPEAQQASGE"
     gene            complement(65859..66482)
                     /gene="clpP"
                     /locus_tag="RN951_000060"
     CDS             complement(65859..66482)
                     /gene="clpP"
                     /locus_tag="RN951_000060"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006809880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDX2525129.1"
                     /translation="MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIF
                     LTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVS
                     TICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
                     GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN"
     gene            complement(66728..68026)
                     /gene="tig"
                     /locus_tag="RN951_000061"
     CDS             complement(66728..68026)
                     /gene="tig"
                     /locus_tag="RN951_000061"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001716227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HDX2525130.1"
                     /translation="MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGF
                     RKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGED
                     FTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEA
                     EDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFP
                     EEYHAENLKGKAAKFAINLKKVEERELPELTAEFIKRFGVEDGSVEGLRAEVRKNMER
                     ELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPR
                     ELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNK
                     ELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMNQQA"
     gene            complement(68370..68687)
                     /gene="bolA"
                     /locus_tag="RN951_000062"
     CDS             complement(68370..68687)
                     /gene="bolA"
                     /locus_tag="RN951_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414969.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator BolA"
                     /protein_id="HDX2525131.1"
                     /translation="MMIRERIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLV
                     SDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYTIKEWEGLQDTVFASPPCRGAG
                     SIA"
     gene            68992..69570
                     /locus_tag="RN951_000063"
     CDS             68992..69570
                     /locus_tag="RN951_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414968.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDX2525132.1"
                     /translation="MFKKILFPLVALFMLAGCAKPPTTIEVSPTITLPQQDPSLMGVT
                     VSINGADQRTDQALAKVTRDNQIVTLTASRDLRFLLQEVLEKQMTARGYMVGPNGPVN
                     LQIIVSQLYADVSQGNVRYNIATKADIAIIATAQNGNKMTKNYRASYNVEGAFQASNK
                     NIADAVNSVLTDTIADMSQDTSIHEFIKQNAR"
     gene            69614..71089
                     /gene="ampG"
                     /locus_tag="RN951_000064"
     CDS             69614..71089
                     /gene="ampG"
                     /locus_tag="RN951_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muropeptide MFS transporter AmpG"
                     /protein_id="HDX2525133.1"
                     /translation="MSSQYLRIFQQPRSAILLILGFASGLPLALTSGTLQAWMTVENI
                     DLKTIGFFSLVGQAYVFKFLWSPLMDRYTPPFFGRRRGWLLATQILLLVAIAAMGFLE
                     PGTQLRWMAALAVVIAFCSASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSG
                     GLALWLADKWLGWQGMYWLMAALLIPCIIATLLAPEPTDTIPVPKTLEQAVVAPLRDF
                     FGRNNAWLILLLIVLYKLGDAFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGA
                     LYGGILMQRLSLFRALLIFGILQGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGT
                     SAFVALLMTLCNKSFSATQFALLSALSAVGRVYVGPVAGWFVEAHGWSTFYLFSVAAA
                     VPGLILLLVCRQTLEYTRVNDNFISRTAYPAGYAFAMWTLAAGVSLLAVWLLLLTMDA
                     LDLTHFSFLPALLEVGVLVALSGVVLGGLLDYLALRKTHLT"
     gene            71549..72496
                     /gene="cyoA"
                     /locus_tag="RN951_000065"
     CDS             71549..72496
                     /gene="cyoA"
                     /locus_tag="RN951_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit II"
                     /protein_id="HDX2525134.1"
                     /translation="MRLRKYNKSLGWLSLFAGTVLLSGCNSALLDPKGQIGLEQRSLI
                     LTAFGLMLIVVIPAILMAVGFAWKYRASNKDAKYSPNWSHSNKVEAVVWTVPILIIIF
                     LAVLTWKTTHALEPSKPLAHDEKPITIEVVSMDWKWFFIYPEQGIATVNEIAFPANTP
                     VYFKVTSNSVMNSFFIPRLGSQIYAMAGMQTRLHLIANEPGTYDGISASYSGPGFSGM
                     KFKAIATPDRAAFDQWVAKAKQSPNTMSDMAAFEKLAAPSEYNQVEYFSNVKPDLFAD
                     VINKFMAHGKSMDMTQPEGEHSAHEGMEGMDMSHAESAH"
     gene            72518..74509
                     /gene="cyoB"
                     /locus_tag="RN951_000066"
     CDS             72518..74509
                     /gene="cyoB"
                     /locus_tag="RN951_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002444673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit I"
                     /protein_id="HDX2525135.1"
                     /translation="MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYL
                     WKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQI
                     FTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSL
                     GVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAP
                     GMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYI
                     NLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHH
                     FFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFS
                     VGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNE
                     TWGKRAFWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALG
                     ILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHERDAFWE
                     MKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIIT
                     WIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLKNGN"
     gene            74499..75113
                     /locus_tag="RN951_000067"
     CDS             74499..75113
                     /locus_tag="RN951_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit III"
                     /protein_id="HDX2525136.1"
                     /translation="MATDTLTHATAHAHEHGHHDAGGTKIFGFWIYLMSDCILFSILF
                     ATYAVLVNGTAGGPTGKDIFELPFVLVETFLLLFSSITYGMAAIAMYKNNKSQVISWL
                     ALTWLFGAGFIGMEIYEFHHLIVNGMGPDRSGFLSAFFALVGTHGLHVTSGLIWMAVL
                     MVQIARRGLTSTNRTRIMCLSLFWHFLDVVWICVFTVVYLMGAM"
     gene            75113..75442
                     /locus_tag="RN951_000068"
     CDS             75113..75442
                     /locus_tag="RN951_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit IV"
                     /protein_id="HDX2525137.1"
                     /translation="MSHSTDHSGASHGSVKTYMTGFILSIILTVIPFWMVMTGAASPA
                     VILGTILAMAVVQVLVHLVCFLHMNTKSDEGWNMTAFVFTVLIIAILVVGSIWIMWNL
                     NYNMMMH"
     gene            75454..76344
                     /gene="cyoE"
                     /locus_tag="RN951_000069"
     CDS             75454..76344
                     /gene="cyoE"
                     /locus_tag="RN951_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX farnesyltransferase"
                     /protein_id="HDX2525138.1"
                     /translation="MMFKQYLQVTKPGIIFGNLISVIGGFLLASKGSIDYPLFIYTLV
                     GVSLVVASGCVFNNYIDRDIDRKMERTKNRVLVKGLISPAVSLVYATLLGIAGFMLLW
                     FGANPLACWLGVMGFVVYVGVYSLYMKRHSVYGTLIGSLSGAAPPVIGYCAVTGEFDS
                     GAAILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKNHITLYIIAFAV
                     ATLMLSLGGYAGYKYLVVAAAVSVWWLGMALRGYKVADDRIWARKLFGFSIIAITALS
                     VMMSVDFMVPDSHTLLAAVW"
     gene            76493..77857
                     /locus_tag="RN951_000070"
     CDS             76493..77857
                     /locus_tag="RN951_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414961.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2525139.1"
                     /translation="MNDYKMTPGERRATWGLGTVFSLRMLGMFMVLPVLTTYGMALQG
                     ASEALIGIAIGIYGLTQAVFQIPFGLLSDRIGRKPLIVGGLAVFAAGSVIAALSDSIW
                     GIILGRALQGSGAIAAAVMALLSDLTREQNRTKAMAFIGVSFGITFAIAMVLGPIITH
                     KLGLHALFWMIAILATTGIALTIWVVPNSSTHVLNRESGMVKGSFSKVLAEPRLLKLN
                     FGIMCLHILLMSTFVALPGQLADAGFPAAEHWKVYLATMLIAFGSVVPFIIYAEVKRK
                     MKQVFVFCVGLIVVAEIVLWNAQTQFWQLVVGVQLFFVAFNLMEALLPSLISKESPAG
                     YKGTAMGVYSTSQFLGVAIGGSLGGWINGMFDGQGVFLAGAMLAAVWLTVASTMKEPP
                     YVSSLRIEIPANIAANEALKVRLLETEGIKEVLIAEEEHSAYVKIDSKVTNRFEIEQA
                     IRQA"
     gene            complement(77985..78476)
                     /gene="yajQ"
                     /locus_tag="RN951_000071"
     CDS             complement(77985..78476)
                     /gene="yajQ"
                     /locus_tag="RN951_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414960.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide binding protein YajQ"
                     /protein_id="HDX2525140.1"
                     /translation="MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDA
                     SKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGI
                     ESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKN
                     FRD"
     gene            78644..79555
                     /gene="panE"
                     /locus_tag="RN951_000072"
     CDS             78644..79555
                     /gene="panE"
                     /locus_tag="RN951_000072"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDX2525141.1"
                     /translation="MKITVLGCGALGQLWLTALCKQGHEVQGWLRVPQPYCSVNLVET
                     DGSIFNESLTANDPDFLATSDLLLVTLKAWQVSDAVKSLASTLPVTTPILLIHNGMGT
                     IEELQNIQQPLLMGTTTHAARRDGNVIIHVANGITHIGPARQQDGDYSYLADILQTVL
                     PDVAWHNNIRAELWRKLAVNCVINPLTAIWNCPNGELRHHPQEIMQICEEVAAVIERE
                     GHHTSAEDLRDYVMQVIDATAENISSMLQDIRALRHTEIDYINGFLLRRARAHGIAVP
                     ENTRLFEMVKRKESEYERIGTGLPRPW"
     gene            79518..80108
                     /gene="yajL"
                     /locus_tag="RN951_000073"
     CDS             79518..80108
                     /gene="yajL"
                     /locus_tag="RN951_000073"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414958.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein deglycase YajL"
                     /protein_id="HDX2525142.1"
                     /translation="MSASALVCLAPGSEETEAVTTIDLLVRGGIKVTTASVASDGNLA
                     ITCSRDVKLLADAPLVEVADGEYDVIVLPGGIKGAECFRDSTLLVETVKQFHRSGRIV
                     AAICAAPATVLVPHDIFPIGNMTGFPTLKDKIPAEQWLDKRVVWDARVKLLTSQGPGT
                     AIDFGLKIIDLLVGREKAHEVASQLVMAAGIYNYYE"
     gene            complement(80162..81610)
                     /gene="thiI"
                     /locus_tag="RN951_000074"
     CDS             complement(80162..81610)
                     /gene="thiI"
                     /locus_tag="RN951_000074"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HDX2525143.1"
                     /translation="MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVV
                     RHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQL
                     EGKTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPDVTVHLEVEDDRLL
                     LIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEI
                     GVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVA
                     ERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTE
                     DFARTMPEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTE
                     QEVVEVETVNGFGPNDVILDIRSIDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQNK
                     TWLLWCERGVMSRLQALYLREQGFNNVKVYRP"
     gene            81816..82058
                     /gene="xseB"
                     /locus_tag="RN951_000075"
     CDS             81816..82058
                     /gene="xseB"
                     /locus_tag="RN951_000075"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HDX2525144.1"
                     /translation="MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQ
                     LARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE"
     gene            82058..82957
                     /gene="ispA"
                     /locus_tag="RN951_000076"
     CDS             82058..82957
                     /gene="ispA"
                     /locus_tag="RN951_000076"
                     /EC_number="2.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl diphosphate synthase"
                     /protein_id="HDX2525145.1"
                     /translation="MDFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGG
                     KRLRPFLVYATGHMFGVSTNTLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPTCH
                     VKFGEANAILAGDALQTLAFSILSDADMPEVSDRDRISMISELASASGIAGMCGGQAL
                     DLDAEGKHVPLDALERIHRHKTGALIRAAVRLGALSAGDKGRRALPVLDKYAESIGLA
                     FQVQDDILDVVGDTATLGKRQGADQQLGKSTYPALLGLEQARKKARDLIDDARQSLKQ
                     LAEQSLDTSALEALADYIIQRNK"
     gene            82982..84844
                     /gene="dxs"
                     /locus_tag="RN951_000077"
     CDS             82982..84844
                     /gene="dxs"
                     /locus_tag="RN951_000077"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HDX2525146.1"
                     /translation="MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVS
                     RSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKG
                     GLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMA
                     FEAMNHAGDIRPDMLVILNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSG
                     VPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQ
                     FLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAA
                     KDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIY
                     STFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMT
                     PSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAI
                     LNFGTLMPEAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAG
                     SGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA"
     gene            85024..85998
                     /gene="yajO"
                     /locus_tag="RN951_000078"
     CDS             85024..85998
                     /gene="yajO"
                     /locus_tag="RN951_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414953.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxyxylulose-5-phosphate synthase YajO"
                     /protein_id="HDX2525147.1"
                     /translation="MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPII
                     KRALEGGINFFDTANSYSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSR
                     AQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
                     ASQFAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLASGR
                     LTRPWGETTARLVSDEVGKNLYKESDENDAQIAERLTGVSEELGATRAQVALAWLLSK
                     PGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPVVGFK"
     gene            complement(86052..86570)
                     /gene="pgpA"
                     /locus_tag="RN951_000079"
     CDS             complement(86052..86570)
                     /gene="pgpA"
                     /locus_tag="RN951_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HDX2525148.1"
                     /translation="MTILPRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLA
                     AIPFWYLMTFLPWQLYSLVVMLGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITL
                     MALPTNDWQWVAAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILY
                     FIGHHWPLGILS"
     gene            complement(86548..87525)
                     /gene="thiL"
                     /locus_tag="RN951_000080"
     CDS             complement(86548..87525)
                     /gene="thiL"
                     /locus_tag="RN951_000080"
                     /EC_number="2.7.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate kinase"
                     /protein_id="HDX2525149.1"
                     /translation="MACGEFSLIARYFDRVRSSRLDVELGIGDDCALLNIPEKQTLAI
                     STDTLVAGNHFLPDIDPADLAYKALAVNLSDLAAMGADPAWLTLALTLPDVDEAWLES
                     FSDSLFDLLNYYDMQLIGGDTTRGPLSMTLGIHGFVPMGRALTRSGAKPGDWIYVTGT
                     PGDSAAGLAILQNRLQVADAKDADYLIKRHLRPSPRILQGQALRDLANSAIDLSDGLI
                     SDLGHIVKASDCGARIDLALLPFSDALSRHVEPEQALRWALSGGEDYELCFTVPELNR
                     GALDVALGHLGVPFTCIGQMTADIEGLCFIRDGEPVTLDWKGYDHFATP"
     gene            complement(87603..88022)
                     /gene="nusB"
                     /locus_tag="RN951_000081"
     CDS             complement(87603..88022)
                     /gene="nusB"
                     /locus_tag="RN951_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HDX2525150.1"
                     /translation="MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVD
                     VLYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQVEKAVLRIALYELSKRSDVPYKV
                     AINEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK"
     gene            complement(88042..88512)
                     /gene="ribE"
                     /locus_tag="RN951_000082"
     CDS             complement(88042..88512)
                     /gene="ribE"
                     /locus_tag="RN951_000082"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HDX2525151.1"
                     /translation="MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQV
                     KDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLA
                     HVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA"
     gene            complement(88601..89704)
                     /gene="ribD"
                     /locus_tag="RN951_000083"
     CDS             complement(88601..89704)
                     /gene="ribD"
                     /locus_tag="RN951_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HDX2525152.1"
                     /translation="MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQ
                     RAGEPHAEVHALRMAGEKAKGATAYVTLEPCSHHGRTPPCCDALIAAGVARVVASMQD
                     PNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGR
                     TAMASGESQWITSPQARRDVQLLRAQSHAILTSSATVLADDPALTVRWSELDEQTQAL
                     YPQQNLRQPIRIVIDSQNRVTPVHRIVQQPGETWFARTQEDSREWPETVRTLLIPEHK
                     GHLDLVVLMMQLGKQQINSIWVEAGPTLAGALLQAGLVDELIVYIAPKLLGSDARGLC
                     TLPGLEKLADAPQFKFKEIRHVGPDVCLHLVGA"
     gene            complement(89708..90157)
                     /gene="nrdR"
                     /locus_tag="RN951_000084"
     CDS             complement(89708..90157)
                     /gene="nrdR"
                     /locus_tag="RN951_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HDX2525153.1"
                     /translation="MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVA
                     ELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGERE
                     VPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED"
     gene            90308..90847
                     /locus_tag="RN951_000085"
     CDS             90308..90847
                     /locus_tag="RN951_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414946.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3251 domain-containing protein"
                     /protein_id="HDX2525154.1"
                     /translation="MNTNVFRLLLLGSLFSLSACVQQSEVRQMKHSVSTLNQEMTQLN
                     QETVKITQQNRLNAKSSSGVYLLPGAKTPARLESQIGTLRMSLVNITPDADGTTLTLR
                     IQGESNDPLPAFSGTVEYGQIQGTIDNFQEINVQNQLINAPASVLAPSDVDIPLQLKG
                     ISVDQLGFVRIHDIQPVMQ"
     gene            91146..92030
                     /gene="tsx"
                     /locus_tag="RN951_000086"
     CDS             91146..92030
                     /gene="tsx"
                     /locus_tag="RN951_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-specific channel-forming protein Tsx"
                     /protein_id="HDX2525155.1"
                     /translation="MKKTLLAAGAVLALSSSFTVNAAENDKPQYLSDWWHQSVNVVGS
                     YHTRFGPQIRNDTYLEYEAFAKKDWFDFYGYADAPVFFGGNSDAKGIWNHGSPLFMEI
                     EPRFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNKDGRQSTWYMGLGTDIDTGLPMS
                     LSMNVYAKYQWQNYGAANENEWDGYRFKIKYFVPITDLWGGQLSYIGFTNFDWGSDLG
                     DDSGNAINGIKTRTNNSIASSHILALNYDHWHYSVVARYWHDGGQWNDDAELNFGNGN
                     FNVRSTGWGGYLVVGYNF"
     gene            complement(92207..92554)
                     /locus_tag="RN951_000087"
     CDS             complement(92207..92554)
                     /locus_tag="RN951_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH nuclease family protein"
                     /protein_id="HDX2525156.1"
                     /translation="MAIIPKNYARLESGYREKALKIYPWVCGRCSREFVYSNLRELTV
                     HHIDHGHTNNPEDGSNWELLCLYCHDHEHSKYTEADQYGTTVIAGEDAQKDVGEAKYN
                     PFADLKAMMNKKK"
     gene            complement(92683..93654)
                     /gene="secF"
                     /locus_tag="RN951_000088"
     CDS             complement(92683..93654)
                     /gene="secF"
                     /locus_tag="RN951_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecF"
                     /protein_id="HDX2525157.1"
                     /translation="MAQEYTVEQLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVR
                     GFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVRMPPAE
                     GETGGQVLGSQVLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVY
                     VGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVS
                     DRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLT
                     MLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPSILP"
     gene            complement(93665..95512)
                     /gene="secD"
                     /locus_tag="RN951_000089"
     CDS             complement(93665..95512)
                     /gene="secD"
                     /locus_tag="RN951_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecD"
                     /protein_id="HDX2525158.1"
                     /translation="MLNRYPLWKYVMLIVVIVIGLLYALPNLFGEDPAVQITGARGVA
                     ASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDSTDTQLRAREALMGVMGDKYVVA
                     LNLAPATPRWLAAIHAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLRE
                     KGIPYTTVRKENNYGLSITFRDAKARDEAIAYLSKRHPDLVISSQGSNQLRAVMSDAR
                     LSEAREYAVQQNINILRNRVNQLGVAEPVVQRQGADRIVVELPGIQDTARAKEILGAT
                     ATLEFRLVNTNVDQAAAASGRVPGDSEVKQTREGQPVVLYKRVILTGDHITDSTSSQD
                     EYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEV
                     INIANIQSRLGNSFRITGINNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNI
                     EQGLEACLAGLLVSILFMIIFYKKFGLIATSALIANLILIVGIMSLLPGATLSMPGIA
                     GIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANITTLIKVII
                     LYAVGTGAIKGFAITTGIGVATSMFTAIVGTRAIVNLLYGGKRVKKLSI"
     gene            complement(95540..95872)
                     /gene="yajC"
                     /locus_tag="RN951_000090"
     CDS             complement(95540..95872)
                     /gene="yajC"
                     /locus_tag="RN951_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HDX2525159.1"
                     /translation="MSFFISDAVAATGAPAQGSPMSLILMLVVFGLIFYFMILRPQQK
                     RTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENGYIAIALNDTTEVVIKRDFVAAVL
                     PKGTMKAL"
     gene            complement(95895..97022)
                     /gene="tgt"
                     /locus_tag="RN951_000091"
     CDS             complement(95895..97022)
                     /gene="tgt"
                     /locus_tag="RN951_000091"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HDX2525160.1"
                     /translation="MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPE
                     EVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIR
                     KITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSME
                     MSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVG
                     EPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGH
                     LFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHN
                     LRYYQRLMAGLRKAIEEGKLESLVTDFYQRQGREVPPLNVD"
     gene            complement(97078..98148)
                     /gene="queA"
                     /locus_tag="RN951_000092"
     CDS             complement(97078..98148)
                     /gene="queA"
                     /locus_tag="RN951_000092"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HDX2525161.1"
                     /translation="MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFT
                     DLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPK
                     PGAELLLGDDESINATMTARHGALFEVEFNDERSVLDILNSIGHMPLPPYIDRPDEDA
                     DRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVD
                     TIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPF
                     FDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRF
                     FSYGDAMFITYNPQAINERVGE"
     gene            98241..98822
                     /gene="acpH"
                     /locus_tag="RN951_000093"
     CDS             98241..98822
                     /gene="acpH"
                     /locus_tag="RN951_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP phosphodiesterase"
                     /protein_id="HDX2525162.1"
                     /translation="MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHM
                     HRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFV
                     CYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALR
                     DSWYDLDAHYDALETRFWQFYPRMMAQASRKAL"
     gene            complement(98827..100644)
                     /gene="malZ"
                     /locus_tag="RN951_000094"
     CDS             complement(98827..100644)
                     /gene="malZ"
                     /locus_tag="RN951_000094"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin glucosidase"
                     /protein_id="HDX2525163.1"
                     /translation="MMLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDN
                     EEMSVPMHKQRSQPQPGVTAWRAAIDLSSGQPRRRYSFKLLWHDRQRWFTPQGFSRMP
                     PARLEQFAVDVPDIGPQWAADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILR
                     DWDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEAYR
                     HVDPQFGGDGALLRLRHNTQQLGMRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPES
                     PWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSIVRHWLKAPWNMDGW
                     RLDVVHMLGEAGGARNNMQHVAGITEAAKETQPEAYIVGEHFGDARQWLQADVEDAAM
                     NYRGFTFPLWGFLANTDISYDPQQIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDT
                     ARFKTLLGRDIARLPLAVVWLFTWPGVPCIYYGDEVGLDGKNDPFCRKPFPWQVEKQD
                     TALFALYQRMIALRKKSQALRHGGCQVLYAEDNVVVFVRVLNQQRVLVAINRGEACEV
                     VLPASPFLNAVQWQCKEGHGQLTDGILALPAISATVWMN"
     gene            complement(100800..102173)
                     /gene="proY"
                     /locus_tag="RN951_000095"
     CDS             complement(100800..102173)
                     /gene="proY"
                     /locus_tag="RN951_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline-specific permease ProY"
                     /protein_id="HDX2525164.1"
                     /translation="MESKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSV
                     LLAYIIGGIAAYIIMRALGEMSVHNPAASSFSRYAQENLGPLAGYITGWTYCFEILIV
                     AIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATI
                     IIMIVAGFGIIIWGIGNGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEII
                     GITAGEAKDPEKSIPRAINSVPMRILVFYVGTLFVIMSIYPWNQVGTAGSPFVLTFQH
                     MGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPKIFSKTSRRGIPWVT
                     VLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVK
                     ALKFKVPGGVATTIGGLIFLLFIIGLIGYHPDTRISLYVGFAWIVVLLIGWMFKRRHD
                     RQLAENQ"
     gene            complement(102249..103568)
                     /gene="brnQ"
                     /locus_tag="RN951_000096"
     CDS             complement(102249..103568)
                     /gene="brnQ"
                     /locus_tag="RN951_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transporter carrier
                     protein BrnQ"
                     /protein_id="HDX2525165.1"
                     /translation="MTHQLRSRDIIALGFMTFALFVGAGNIIFPPMVGLQAGEHVWTA
                     AFGFLITAVGLPVLTVVALAKVGGGVDSLSTPIGKVAGVLLATVCYLAVGPLFATPRT
                     ATVSFEVGIAPLTGDSALPLFIYSLVYFAIVILVSLYPGKLLDTVGNFLAPLKIIALV
                     ILSVAAIVWPAGSISTATEAYQNAAFSNGFVNGYLTMDTLGAMVFGIVIVNAARSRGV
                     TEARLLTRYTVWAGLMAGVGLTLLYLALFRLGSDSASLVDQSANGAAILHAYVQHTFG
                     GGGSFLLAALIFIACLVTAVGLTCACAEFFAQYVPLSYRTLVFILGGFSMVVSNLGLS
                     QLIQISVPVLTAIYPPCIALVVLSFTRSWWHNSSRVIAPPMFISLLFGILDGIKASAF
                     SDILPSWAQRLPLAEQGLAWLMPTVVMVVLAIIWDRAAGRQVTSSAH"
     gene            complement(103975..105270)
                     /gene="phoR"
                     /locus_tag="RN951_000097"
     CDS             complement(103975..105270)
                     /gene="phoR"
                     /locus_tag="RN951_000097"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate regulon sensor histidine kinase PhoR"
                     /protein_id="HDX2525166.1"
                     /translation="MLERLSWKRLVLELLLCCLPAFILGAFFGYLPWFLLASVTGLLI
                     WHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGNLIKRFRS
                     GAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFTQYLKTRD
                     FSRPLNLVLNTGRHLEIRVMPYTHKQLLMVARDVTQMHQLEGARRNFFANVSHELRTP
                     LTVLQGYLEMMNEQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTHLLNE
                     KVDVPMMLRVVEREAQTLSQKKQTFTFEIDNGLKVSGNEDQLRSAISNLVYNAVNHTP
                     EGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLA
                     IVKHAVNHHESRLNIESTVGKGTRFSFVIPERLIAKNSD"
     gene            complement(105328..106017)
                     /gene="phoB"
                     /locus_tag="RN951_000098"
     CDS             complement(105328..106017)
                     /gene="phoB"
                     /locus_tag="RN951_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate response regulator transcription
                     factor PhoB"
                     /protein_id="HDX2525167.1"
                     /translation="MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNE
                     PWPDLILLDWMLPGGSGIQFIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDY
                     ITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPTSHRVMAGEEPLEMGPTEF
                     KLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEPGGHDRMVQTV
                     RGTGYRFSTRF"
     gene            106207..107409
                     /gene="sbcD"
                     /locus_tag="RN951_000099"
     CDS             106207..107409
                     /gene="sbcD"
                     /locus_tag="RN951_000099"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcD"
                     /protein_id="HDX2525168.1"
                     /translation="MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQTHQVDAII
                     VAGDVFDTGSPPSYARTLYNRFVVNLQQTGCHLVVLAGNHDSVATLNESRDIMAFLNT
                     TVVASAGHAPQILPRRDGTPGAVLCPIPFLRPRDIITSQAGLNGIEKQQHLLAAITDY
                     YQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFPAQNFPPADYI
                     ALGHIHRAQIIGGMEHVRYCGSPIPLSFDECGKSKYVHLVTFSNGKLESVENLNVPVT
                     QPMAVLKGDLASITAQLEQWRDVSQEPPVWLDIEITTDEYLHDIQRKIQALTESLPVE
                     VLLVRRSREQRERVLASQQRETLSELSVEEVFNRRLALEELDESQQQRLQHLFTTTLH
                     TLAGEHEA"
     gene            107406..110552
                     /gene="sbcC"
                     /locus_tag="RN951_000100"
     CDS             107406..110552
                     /gene="sbcC"
                     /locus_tag="RN951_000100"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcC"
                     /protein_id="HDX2525169.1"
                     /translation="MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKT
                     TLLDAICLALYHETPRLSNVSQSQNDLMTRDTAECLAEVEFEVKGEAYRAFWSQNRAR
                     NQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAA
                     FLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVTLLTPEQV
                     QSLTASLQVLTDEEKQLITAQQQEQQSLNWLTRQDELQQEASRRQQALQQALAEEEKA
                     QPQLAALSLAQPARNLRPHWERIAEHSAALAHIRQQIEEVNTRLQSTMALRASIRHHA
                     AKQSAELQQQQQSLNTWLQEHDRFRQWNNEPAGWRAQFSQQTSDREHLRQWQQQLTHA
                     EQKLNALAAITLTLTADEVATALAQHAEQRPLRQHLVALHGQIVPQQKRLAQLQVAIQ
                     NVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEARIKTLEAQRAQLQAGQPCPL
                     CGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEGATLRGQLDAITKQLQRDENE
                     AQSLRQDEQALTQQWQAVTASLNITLQPLDDIQPWLDAQDEHERQLRLLSQRHELQGQ
                     IAAHNQQIIQYQQQIEQRQQLLLTTLTGYALTLPQEDEEESWLATRQQEAQSWQQRQN
                     ELTALQNRIQQLTPILETLPQSDELPHCEETVVLENWRQVHEQCLALHSQQQTLQQQD
                     VLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQT
                     LVTQTAETLAQHQQHRPDDGLALTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQD
                     ADNRQQQQTLMQQIAQMTQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQ
                     LTRLHGRYLLQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVS
                     HKTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERIPVQIKV
                     KKINGLGYSKLESTFAVK"
     gene            110678..111862
                     /gene="araJ"
                     /locus_tag="RN951_000101"
     CDS             110678..111862
                     /gene="araJ"
                     /locus_tag="RN951_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414930.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter AraJ"
                     /protein_id="HDX2525170.1"
                     /translation="MKKVILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGHMI
                     SYYALGVVVGAPIIALFSSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSG
                     FPHGAFFGVGAIVLSKIIKPGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTF
                     LLIAVFNIAVMASVYFWVPDIRDEAKGNLREQFHFLRSPAPWLIFAATMFGNAGVFAW
                     FSYVKPYMMFISGFSETAMTFIMMLVGLGMVLGNMLSGRISGRYSPLRIAAVTDFIIV
                     LALLMLFFCGGMKTTSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAFN
                     LGSAVGAYCGGMMLTLGLAYNYVALPAALLSFAAMSSLLLYGRYKRQQAADTPVLAKP
                     LG"
     gene            complement(112107..113015)
                     /gene="mak"
                     /locus_tag="RN951_000102"
     CDS             complement(112107..113015)
                     /gene="mak"
                     /locus_tag="RN951_000102"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414928.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase"
                     /protein_id="HDX2525171.1"
                     /translation="MRIGIDLGGTKTEVIALGDAGEQLYRHRLPTPRDDYRQTIETIA
                     TLVDMAEQATGQRGTVGMGIPGSISPYTGVVKNANSTWLNGQPFDKDLSARLQREVRL
                     ANDANCLAVSEAVDGAAAGAQTVFAVIIGTGCGAGVAFNGRAHIGGNGTAGEWGHNPL
                     PWMDEDELRYREEVPCYCGKQGCIETFISGTGFAMDYRRLSGHALKGSEIIRLVEESD
                     PVAELALRRYELRLAKSLAHVVNILDPDVIVLGGGMSNVDRLYQTVGQLIKQFVFGGE
                     CETPVRKAKHGDSSGVRGAAWLWPQE"
     gene            113140..114051
                     /gene="rdgC"
                     /locus_tag="RN951_000103"
     CDS             113140..114051
                     /gene="rdgC"
                     /locus_tag="RN951_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-associated protein RdgC"
                     /protein_id="HDX2525172.1"
                     /translation="MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMG
                     WVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQARKLKKT
                     EKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGS
                     LPVVPLSMENPIELTLTEWVRSGSAAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEE
                     ITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFD
                     ADFILMTGELAALIQNLIEGLGGEAQR"
     gene            complement(114129..114212)
                     /locus_tag="RN951_000104"
     CDS             complement(114129..114212)
                     /locus_tag="RN951_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2525173.1"
                     /translation="MTQRPWSKLQRKTHNIAALKIIARRSE"
     gene            complement(114209..114550)
                     /locus_tag="RN951_000105"
                     /pseudo
     CDS             complement(114209..114550)
                     /locus_tag="RN951_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308469.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2773 domain-containing protein"
     gene            complement(114698..114982)
                     /gene="ppnP"
                     /locus_tag="RN951_000106"
     CDS             complement(114698..114982)
                     /gene="ppnP"
                     /locus_tag="RN951_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HDX2525174.1"
                     /translation="MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEE
                     MTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL"
     gene            complement(115054..115731)
                     /locus_tag="RN951_000107"
     CDS             complement(115054..115731)
                     /locus_tag="RN951_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AroM family protein"
                     /protein_id="HDX2525175.1"
                     /translation="MSASLAILTIGIVPMQEVLPLLTEYIDEDNISHHSLLGKLSREE
                     VMAEYAPEAGEDTILTLLNDNQLAHVSRRKVERDLQGVVEVLDNQGYDVILLMSTANI
                     SSMTARNTIFLEPSRILPPLVSSIVEDHQVGVIVPVEEMLPVQAQKWQILQKSPVFSL
                     GNPIHDSEQKIIDAGKELLAKGADVIMLDCLGFHQRHRDLLQKQLDVPVLLSNVLIAR
                     LAAELLV"
     gene            complement(115989..116180)
                     /gene="yaiA"
                     /locus_tag="RN951_000108"
     CDS             complement(115989..116180)
                     /gene="yaiA"
                     /locus_tag="RN951_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YaiA"
                     /protein_id="HDX2525176.1"
                     /translation="MPTKPPYPREAYIVTIEKGKPGQTVTWYQLRADHPKPDSLISEH
                     PTAQEAMDAKKRYEDPDKE"
     gene            complement(116230..116754)
                     /gene="aroL"
                     /locus_tag="RN951_000109"
     CDS             complement(116230..116754)
                     /gene="aroL"
                     /locus_tag="RN951_000109"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroL"
                     /protein_id="HDX2525177.1"
                     /translation="MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMT
                     VAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCA
                     PVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQV
                     ISEIRSALAQTINC"
     gene            complement(116937..117395)
                     /locus_tag="RN951_000110"
     CDS             complement(116937..117395)
                     /locus_tag="RN951_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414921.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HDX2525178.1"
                     /translation="MTIWVDADACPNVIKEILYRAAERMQMPLVLVANQSLRVPPSRF
                     IRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEAIEKGAAALNPRGERYTPATI
                     RERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRSRG"
     gene            117515..118324
                     /gene="proC"
                     /locus_tag="RN951_000111"
     CDS             117515..118324
                     /gene="proC"
                     /locus_tag="RN951_000111"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDX2525179.1"
                     /translation="MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVAA
                     LHDQFGINAAESAQEVAQIADIIFAAVKPGIMIKVLSEITSSLNKDSLVVSIAAGVTL
                     DQLARALGHDRKIIRAMPNTPALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVI
                     AEPMIHPVVGVSGSSPAYVFMFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLET
                     GEHPGALKDMVCSPGGTTIEAVRVLEEKGFRAAVIEAMTKCMEKSEKLSKS"
     gene            complement(118341..119456)
                     /gene="adrA"
                     /locus_tag="RN951_000112"
                     /gene_synonym="dgcC"
     CDS             complement(118341..119456)
                     /gene="adrA"
                     /locus_tag="RN951_000112"
                     /gene_synonym="dgcC"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase AdrA"
                     /protein_id="HDX2525180.1"
                     /translation="MFPKIMNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLP
                     RAVGLAGMFLPIASTLVSHPPPGWWWLVLVGWAFVWPHLAWQIASRAVDPLSREIYNL
                     KTDAVLAGMWVGVMGVNVLPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLEL
                     TGITVSFNSAPLEWWLSLPIIVIYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGV
                     YNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQ
                     ITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVHEGLNTLRLPNTPQVTLRISVG
                     VAPLNPQMSHYREWLKSADLALYKAKKAGRNRTEVAA"
     gene            complement(119558..119878)
                     /gene="psiF"
                     /locus_tag="RN951_000113"
     CDS             complement(119558..119878)
                     /gene="psiF"
                     /locus_tag="RN951_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414918.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PsiF"
                     /protein_id="HDX2525181.1"
                     /translation="MKITLLVTLLFGLVFLTTVGAAERTLTPQQQRMTSCNQQATAQA
                     LKGDARKTYMSDCLKNSKSAPGEKSLTPQQQKMRECNNQATQQSLKGDDRNKFMSACL
                     KKAA"
     gene            complement(119997..121412)
                     /gene="phoA"
                     /locus_tag="RN951_000114"
     CDS             complement(119997..121412)
                     /gene="phoA"
                     /locus_tag="RN951_000114"
                     /EC_number="3.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414917.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase"
                     /protein_id="HDX2525182.1"
                     /translation="MKQSTIALALLPLLFTPVTKARTPEMPVLENRAAQGDITAPGGA
                     RRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPL
                     TGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKA
                     AGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLL
                     NARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKP
                     LLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSK
                     NEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADH
                     AHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAAN
                     VVGLTDQTDLFYTMKAALGLK"
     gene            complement(121513..121773)
                     /gene="iraP"
                     /locus_tag="RN951_000115"
     CDS             complement(121513..121773)
                     /gene="iraP"
                     /locus_tag="RN951_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraP"
                     /protein_id="HDX2525183.1"
                     /translation="MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQND
                     QQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKLLKHPRQ"
     gene            complement(121955..122158)
                     /locus_tag="RN951_000116"
     CDS             complement(121955..122158)
                     /locus_tag="RN951_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2525184.1"
                     /translation="MLQSSADKACNVLVKKVRYLKDVRKITKMMNGKLIYSWLKWPCG
                     EFFSLNYKLTKRIYFITFIYNKG"
     gene            122236..123330
                     /gene="ddlA"
                     /locus_tag="RN951_000117"
     CDS             122236..123330
                     /gene="ddlA"
                     /locus_tag="RN951_000117"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDX2525185.1"
                     /translation="MEKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKSRFDVVLLGID
                     KQGQWHVSDASNYLLNADDPAHIALRPSATSLAQVPGKHEHQLIDAQNGQPLPTVDVI
                     FPIVHGTLGEDGSLQGMLRVANLPFVGSDVLASAACMDKDVTKRLLRDAGLNIAPFIT
                     LTRANRHNISFAEVESKLGLPLFVKPANQGSSVGVSKVTSEEQYAIAVDLAFEFDHKV
                     IVEQGIKGREIECAVLGNDNPQASTCGEIVLTSDFYAYDTKYIDEDGAKVVVPAAIAP
                     EINDKIRAIAVQAYQTLGCAGMARVDVFLTPENEVVINEINTLPGFTNISMYPKLWQA
                     SGLGYTDLITRLIELALERHAADNALKTTM"
     gene            complement(123354..123566)
                     /locus_tag="RN951_000118"
     CDS             complement(123354..123566)
                     /locus_tag="RN951_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414914.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2754 domain-containing protein"
                     /protein_id="HDX2525186.1"
                     /translation="MNLPVKIRRDWHYYAFAIGLIFILNGVVGLLGFEAKGWQTYAVG
                     LVTWVISFWLAGLIIRRRDEETENAQ"
     gene            123826..124134
                     /locus_tag="RN951_000119"
     CDS             123826..124134
                     /locus_tag="RN951_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiY family protein"
                     /protein_id="HDX2525187.1"
                     /translation="MADFTLSKSLFSGKYRNASSTPGNIAYALFVLFCFWAGAQLLNL
                     LVHAPGVYERLMQVQETGRPRVEIGLGVGTIFGLIPFLVGCLIFAVVALWLHWRHRRQ
                     "
     gene            complement(124193..125287)
                     /gene="yaiW"
                     /locus_tag="RN951_000120"
     CDS             complement(124193..125287)
                     /gene="yaiW"
                     /locus_tag="RN951_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-exposed outer membrane lipoprotein YaiW"
                     /protein_id="HDX2525188.1"
                     /translation="MSRVNPLSSLSLLAVLVLAGCSSQAPQPLKKGEKAIDVASVVRQ
                     KMPASVKDRDAWAKDLATTFESQGLAPTLENVCSVLAVAQQESNYQADPAVPGLSKIA
                     WQEIDRRAERMHIPAFLVHTALKIKSPNGKSYSERLDSVRTEKQLSAIFDDLINMVPM
                     GQTLFGSLNPVRTGGPMQVSIAFAEQHTKGYPWKMDGTVRQEVFSRRGGLWFGTYHLL
                     NYPASYSAPIYRFADFNAGWYASRNAAFQNAVSKASGVKLALDGDLIRYDSKEPGKTE
                     LATRKLAAKLGMSDSEIRRQLEKGDSFSFEETALYKKVYQLAETKTGKSLPREMLPGI
                     QLESPKITRNLTTAWFAKRVDERRARCMKQ"
     gene            complement(125300..126520)
                     /gene="sbmA"
                     /locus_tag="RN951_000121"
     CDS             complement(125300..126520)
                     /gene="sbmA"
                     /locus_tag="RN951_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide antibiotic transporter SbmA"
                     /protein_id="HDX2525189.1"
                     /translation="MFKSFFPKPGTFFLSAFVWALIAVIFWQAGGGDWVARITGASGQ
                     IPISAARFWSLDFLIFYAYYIVCVGLFALFWFIYSPHRWQYWSILGTALIIFVTWFLV
                     EVGVAVNAWYAPFYDLIQTALSSPHKVTIEQFYREVGVFLGIALIAVVISVLNNFFVS
                     HYVFRWRTAMNEYYMANWQQLRHIEGAAQRVQEDTMRFASTLENMGVSFINAIMTLIA
                     FLPVLVTLSAHVPELPIIGHIPYGLVIAAIVWSLMGTGLLAVVGIKLPGLEFKNQRVE
                     AAYRKELVYGEDDATRATPPTVRELFSAVRKNYFRLYFHYMYFNIARILYLQVDNVFG
                     LFLLFPSIVAGTITLGLMTQITNVFGQVRGAFQYLINSWTTLVELMSIYKRLRSFEHE
                     LDGDKIQEVTHTLS"
     gene            126872..128029
                     /gene="ampH"
                     /locus_tag="RN951_000122"
     CDS             126872..128029
                     /gene="ampH"
                     /locus_tag="RN951_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine-
                     carboxypeptidase/endopeptidase AmpH"
                     /protein_id="HDX2525190.1"
                     /translation="MKRSLLFSAVLCAASLTSVHAAQPITEPEFASDIVDRYADHIFY
                     GSGATGMALVVIDGNQRVFRSYGETRPGNNVRPQLDSVVRIASLTKLMTSEMLVKLLD
                     QGTVKLNDPLSKYAPPGARVPTYNGTPITLVNLATHTSALPREQPGGAAHRPVFVWPT
                     REQRWKYLSTAKLKAAPGSQAAYSNLAFDLLADALANASGKPYTQLFEEQITRPLGMK
                     DTTYTPSPDQCRRLMVAERGASPCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYQR
                     SNQADRMQTLIYQRAQFTKVIGMDVPGKADALGLGWVYMAPKEGRPGIIQKTGGGGGF
                     ITYMAMIPQKNIGAFVVVTRSPLTRFKNMSDGINDLVTELSGNKPLVIPAS"
     gene            complement(128030..128653)
                     /gene="iprA"
                     /locus_tag="RN951_000123"
     CDS             complement(128030..128653)
                     /gene="iprA"
                     /locus_tag="RN951_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414909.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogen peroxide resistance inhibitor IprA"
                     /protein_id="HDX2525191.1"
                     /translation="MLSVVKPLQEFGKLDKCLSRYGTRFEFNNEKQVIFSSDVNNEDT
                     FVILEGVISLRREENVLIGITQAPYIMGLADGLMKNDIPYKLISEGNCTGYHLPAKQT
                     ITLIEQNQLWRDAFYWLAWQNRILELRDVQLIGHNSYEQIRATLLSMIDWNEELRSRI
                     GVMNYIHQRTRISRSVVAEVLAALRKGGYIEMNKGKLVAINRLPSEY"
BASE COUNT        30818 a        34254 c        32491 g        31147 t
ORIGIN      
        1 taaagtgccc ttttagttat tgttcatatc cctgtgttag caacaaaaaa aaataaaatg
       61 acacacaaga ccagctaatg tatttatata tttttcacat aaacttattt gttctcaatc
      121 aacaacaact gttattacag gtcactttca atattttatt aaactaacat ttttagcaca
      181 gatgaattca tcatcaacaa attcactata tggataatat ccattcaacg catatgattt
      241 atgattttat tagtctgagt tatttttgta gggctatatt taaaatcaat aaactccacc
      301 gattcagatt aatatcagca atagaaagat aggaaatcac caattcaata acatcatcaa
      361 tgaaacatat tgtagaatta atttaaacaa ggcgttccat tcaaccagaa cgccccttat
      421 ttactctcat caccccgcaa actgcctgaa cagcgcctta cccttaacca gtcgcgcacc
      481 cagccagccg ccgaaaagcg acagcagcag cgctccgctg cacggcagaa caatccacaa
      541 tcgccagtct ggctcccacg gaaaatcaaa cactttcgcc tgcaacactg ccagcgccgt
      601 ttccgcacca attgcggcca ccaggccgga aacaaaccca agcatggcga actcacacca
      661 caacgtggta cgcagcagtt ttttccccgc accgagtgtg cgccacacca ccagctcctg
      721 atgacgctga cgcattccca cctgcacctg tgccagcaac agcaacatac cgcaggcggt
      781 gaccagtacc accatcactt ccagcgcccg acttacctgc tccagcacct gaccgacctg
      841 ttttaaaatc gcgccaatat ctaacaggct aatggtcggg aactggcggt tgagttgtgt
      901 caacatgccg ttgccattct cccagcggaa actggtaagc cagctctgcg gttgcccgtc
      961 taatgcccct tcagggaaaa taaaatagaa attaggccgc agactttccc agtccacttt
     1021 gcgcaggctg gtcactttag cgcggaactc ctgggtatcg cccataaaag tcacggtatc
     1081 accgagggca acgtttaagc gtttcgccag cccctcttcc atcgacactt catcggcttt
     1141 tggcggccag ttaccggcga caatcggatt atgatcgggc cgcgtatttt gccaggtaag
     1201 attgagttcg cggttaagcg cctcatcttc attaccttct gtcggcttat cgttaatcgc
     1261 cgtcagccgc gcccgcacca ccggataaaa cgattccggg actatctgat gttccgcgag
     1321 gaacgctttt agcggtgcta cctgttctgt ggcgatgtta attaaaaagt agttcgggct
     1381 ttctggaggt agctgctgct gccagcggtc gagcagatcg ccacgcaaca ccagcagcag
     1441 tgccagcagc ataaaggaga gcgaaaatgc cgaaagctga cttaacgttg accacggctg
     1501 acgtaacagg cggctaaccg ccaggcgcag aggcagcgat ttcagcgtca tgcggcgaag
     1561 tacattcagc agcatccagc ccagcacacc gcacagcaaa gccagtacta ccgcgcccgc
     1621 cagcaccgcc caaagcagca tgctgccacc cattaatccg gcgagcagca gcacaaccac
     1681 cacactgaca atcggcagat aaaacttcag cggccagacg ttcgctacca catcattacg
     1741 taatacgcgt aaaggctgcg ttgccagcaa caagcgatat ggtcgtagcc ccaccagcag
     1801 cgagatgacc gtcatggtgc caagcgccca cagccacggc cagaggctgg ctggcggtag
     1861 tgcagcaggc agaacgggct tgagcagcac catcaacacg ttttcgaaca acaggcctat
     1921 ggccccaccg gtaacggctg aaagcgtcag caccatcaac cactgaccga cgattagctt
     1981 acgcagttgc gctcgccctg cccccagcgt tttgaggatc gccaccagat cgtagcaact
     2041 gcgacagtaa tgattcatcg ctaccgccac cgctgccact gccagcagca aggtcagaag
     2101 cgccgaaagc agcaggaact gttgcgagcg ttccatcgat cgccccagcg cgccttcgtc
     2161 ctgttccaga ccgtaccagc gttgttcggg tttaagctga ggtaacaacc atttctcata
     2221 gccgtcgagc tggttctcgt tgccgccgaa tttataacgc caggtgaccc gactccccgg
     2281 ctgcacggct ccggttttat cgacatccgc cagattcatc atcagacgcg gagccatctg
     2341 gaaggggtta aaaccggaat ccggttcctg aatcacttct ccggcaatcc gcaaggtggc
     2401 atcgcccacg tcaatggtgt cgcccgtttt caggttaagc agtgccatca ggcgtggggc
     2461 cagcaatacg ctgcccgcct gcggtttcag gccaggggga ttagtttgca gatcgccata
     2521 catcgggtag atatcatcca ccgctttgac gttcgccagc tgcggtgtgt cgcctgcaaa
     2581 ggtcattgtg gcgaaagtca gctgcttgcc gactttcagg ccgcgctttt gcgcttcctc
     2641 cagccacgct tgcggcactt cgcgtgaact gcgcaacgcc cgatcgcccg ccataaactc
     2701 acggctttgc tggcttaagc ccttctccat gcgatcgctg atattgccca gcgccagcac
     2761 gcaggccacc gccaggctta gcgccagcca gacaattaat agcgacggcg aacgccattc
     2821 gcgccagaac caacgtgcaa tcatgcttcc tcctgcaact gcccgttcac cagccgtaag
     2881 cagcggtcgc agcgtgccgc cagttgcagg tcgtgggtca ccataatcaa cgtggtgcca
     2941 tgttcacggt tgagggaaaa cagcaggtcg gcaattttat cgcccgtctg gcggtcaagg
     3001 ttgccggtgg gttcgtcggc aaacagcaca tcaggtcgac cattaaaggc tcgtgccagc
     3061 gccactcgtt gctgttcacc gccggaaagc tgtgccggaa gatgatccag acgtttaccc
     3121 agccctaact gttcgagcaa cgctttcgcc ccgttacgac tttccgcgct actctcaccg
     3181 cgcagcagag ccggaagctc gacgttttcc agcgcgttaa gggtaggaat taacataaat
     3241 gactgaaaaa caaagccgac gtgcttcgcg cgcaactttg cccgcgcttc ttcgtccata
     3301 ttatgtagcg gttgtcccac cagactcact tcgccactgc tgccgtcatc aagcccggcg
     3361 aggatcgcca gcaaggttga cttacccgat cccgactcgc ccaccagtgc gatggtctcg
     3421 ccacgtttga caaccagctc aactccggtg aggatggaga gttcatgctc cccctgaccg
     3481 acggacttct taagatgatg aacttcaaca atgttttccg ctggcatttg cccttcctgt
     3541 tcctggtcct gttaaccttc cgtgccgccg cagcggacac gttattgatt ctgggtgata
     3601 gcctgagcgc cgggtatcga atgtctgcca gcgcggcctg gcctgccttg ttgaatgata
     3661 agtggcagag taaaacgtcg gtagttaatg ccagcatcag cggcgacacc tcgcaacaag
     3721 gactggcgcg ccttccggct ctgctgaaac agcatcagcc gcgttgggtg ctggttgaac
     3781 tgggcggcaa tgacggtttg cgtggttttc agccacagca aaccgagcaa acgctgcgcc
     3841 agattttgca ggatgtcaaa gccgccaacg ctgaaccatt gttaatgcaa atacgtctgc
     3901 ctgcaaacta tggtcgccgt tataatgaag cctttagcgc catttacccc aaactcgcca
     3961 aagagtttga tgttccgctg ctgccctttt ttatggaaga ggtctacctc aagccacaat
     4021 ggatgcagga tgacggtatt catcccaacc gcgacgccca gccgtttatt gccgactgga
     4081 tggcgaagca gttgcagcct ttagtaaatc atgactcata aagcaacgga gatcctgaca
     4141 ggtaaagtta tgcaaaaatc ggtcttaatt accggatgtt ccagtggaat tggcctggaa
     4201 agcgcgctcg aattaaaacg ccagggtttt catgtgctgg caggttgccg gaaaccggat
     4261 gatgttgagc gcatgaacag catgggattt accggcgtgt tgatcgatct ggattcacca
     4321 gaaagtgttg atcgcgcagc cgacgaggtg atcgccctga ccgataattg tctgtatggg
     4381 atctttaaca atgccggatt cggcatgtat ggcccccttt ccaccatcag ccgtgcgcag
     4441 atggaacagc agttttccgc caactttttc ggcgcacacc agctcaccat gcgcctgtta
     4501 cccgcgatgt taccgcacgg tgaagggcgt attgtgatga catcatcggt gatgggatta
     4561 atctccacgc cgggtcgtgg cgcttacgcg gccagtaaat atgcgctgga ggcgtggtca
     4621 gacgcactgc gcatggagct gcgccacagc ggaattaaag tcagcctgat cgaacccggt
     4681 cccattcgta ctcgcttcac cgacaacgtc aaccagacgc aaagtgataa accagtcgaa
     4741 aatcccggca tcgccgcccg ctttacgttg ggaccggaag cggtggtgga caaagtacgc
     4801 catgctttta ttagcgagaa gccgaagatg cgctatccgg tgacgctggt gacctgggcg
     4861 gtaatggtgc ttaagcgcct gctgccgggg cgcgtgatgg acaaaatatt gcaggggtga
     4921 gttgaagcgc gcgcttaagc ccccatgtca aagaaaatat cgacaacaga gagcgactcc
     4981 atgtccgtag aaaatattgt caacattaac gaatctaacc tgcaacaggt tcttgaacag
     5041 tcgatgacca ctccggtgct gttctatttt tggtctgaac gtagccagca ctgtttgcag
     5101 ttaaccccaa ttctggaaag cctcgcggcg cagtacaacg ggcaatttat tctggcgaag
     5161 ctggactgcg acgcggagca gatgattgcc gcgcagtttg gtctgcgtgc gattccgacc
     5221 gtgtatctgt tccagaacgg gcaaccggta gatggcttcc aggggccgca accggaagag
     5281 gcgatccgcg ccctgctgga taaagtgctg ccgcgcgaag aagagctgaa agcgcagcag
     5341 gcgatgcaac tgatgcagga aagcaattac accgatgccc tgccattgct gaaagacgcc
     5401 tggcagttgt cgaatcagaa cggggagatc ggcctgctgc tggcagaaac gctgattgcg
     5461 ctgaaccgtt ctgaagatgc ggaagcggtg ctgaaaacca ttccgttgca ggatcaggac
     5521 acccgctacc aggggctggt ggcgcaaatc gaactgctga agcaggcggc tgatacgccg
     5581 gaaattcaac agttgcaaca gcaggtggcg gagaatccag aagatgccgc actggcgacg
     5641 caactggcgc tgcaactgca tcaggttggg cgcaatgaag aggcgctgga gttgctgttc
     5701 gggcatctgc gtaaagatct caccgccgca gacggtcaga cgcgtaaaac gttccaggag
     5761 atcctcgctg cgctgggtac gggtgatgca ctggcgtcga agtatcgccg ccagctgtat
     5821 gcattgttgt attgatattc cgttgatcgg cacatgaacc acaacgccgg atgcgatgct
     5881 gcgcatccgg catcgcatca tttcttcttc aattgcgtca ccaccaactg gtggcgcgaa
     5941 ttataaaact tacgataggt taaatagcag gcaataatgg tcgacaagct ggcggttgag
     6001 agcagcataa aggtcaccat aatctgatat ttaatcgcct tcaccggatc aatcccggca
     6061 aatatcagcc cggacatcat tcctggtaaa ctcactaagc caaccgtttt tgctgaatcg
     6121 accgtcggaa ttaaagccgc gcgaatactg tcgcgaatca atatcgctga agcctgcttc
     6181 ggcgtcgcac caagactcag tttctcctga atctgttgct gttcgctaat gacccgttgc
     6241 cctaaattgt tgtaacacaa ccccaccgct accatggcgt taccggcaat catcccggcg
     6301 atagggatca cctgcatcgg gataaattca atcgaccctg agagaatcag caccgccagg
     6361 gtaattcccg ccccgaccgt aatggcaata aacgatgaga taaaagcttt agcaatatat
     6421 ttactgcgtt tttgcgcgtt ccacgccgca ttaaagcaga taaataacac catcaataat
     6481 gtcaggctgg catcatccac gctgaaaata tacttcagca catagccgac aataatcagc
     6541 tgaattatcg ctcgcccgac gctccagaga atatctttct ccagcgccag tttttcttta
     6601 tggctaatta agattgccac caccaccagc attaatgcca gtgctaatga ttcgttagta
     6661 atattatgcg agttcatagc gtgcttcctg catttctccg gcatgcggtt gcagtgtaat
     6721 cactttatcc gcatgattaa tttcgtcttt atcgtgtgtc acccacagca cggcaatatt
     6781 ttgctcgcgc acataacgat ggatcatctc attgacgtta tgtttattac tttcatccag
     6841 cgcactggtt atttcatcca gcaataaaac cttcggcata aattgcaggt tacgaatcaa
     6901 tgagatgcgt tgtttttcac caccagatag ctcggcgata ttcttcgtca aaatgctgtc
     6961 cggcaaggcg aagcgttcga gaaaatcgag aaaaatggct gggtcaggct gccggttacg
     7021 gatctgccag ggaaagatca gattatcgta taccgtatcg ccaaacagcg tcggtgtctg
     7081 ggcgcagtaa gagacttgtt ggcggtagat ttctggcttt agtgtgctga catcctcacc
     7141 ttcaaacagt aacgttccgc tggttgggct gatcaatgaa gcaactattt ttagcagcgt
     7201 acttttgcca caaccagaag gaccggtaat taacttaaat tcgccagcac gcagcgaaaa
     7261 attgatgtta ttaagaatct tcgcatcacc cgccagatat cctacgtttt gtagctgaag
     7321 caaaggacta ttttcctgca tcgctgttcc ctttttctga tttttactaa aaacagttta
     7381 tccttcgcag gaataagggg gaactctctt tcagtaatca ggtataattt gtttaatcaa
     7441 gcagcaattt tgctgattat ggacggtaca acaggaggtt tttccgatgc ttatctttat
     7501 cccgattctc atttttgtcg cgctggtcat tgtcggcgcg ggtgtcaaaa tcgtaccgca
     7561 gggctatcag tggacagtag aacgctttgg tcgctatacc aaaacgttac agccggggct
     7621 cagtctggtg gtgccgttta tggatcgcat tggtcgcaag atcaatatga tggagcaagt
     7681 gctcgatatc ccttcccagg aagttatctc gaaagataac gccaacgtta ccatcgacgc
     7741 cgtgtgcttt attcaggtga ttgacgcgcc gcgcgcggct tatgaagtca gcaatctgga
     7801 gctggcgatc atcaacctga ccatgactaa catccgtacc gtgctgggtt caatggaact
     7861 tgacgaaatg ctctctcagc gcgacagcat caactcacgc ctgctgcgta ttgtcgatga
     7921 agccaccaac ccgtggggga ttaaagtcac ccgtattgaa attcgcgacg tgcgcccacc
     7981 ggcagagctt atctcttcaa tgaacgcgca gatgaaagcg gaacgtacca aacgcgctta
     8041 cattcttgaa gcggaaggga tccgtcaggc ggaaatcctc aaagccgaag gtgaaaaaca
     8101 gtcgcaaatc ctgaaagcgg aaggcgaacg tcagtcggcg tttttacagg ctgaagcgcg
     8161 tgaacgttcc gccgaagcag aagcccgcgc caccaaaatg gtgtctgaag ctatcgcctc
     8221 cggtgatatt caggcggtga actacttcgt agcgcagaaa tacaccgaag cgttacagca
     8281 gatcggttcc tccagtaaca gcaaagtagt gatgatgcca ttagaggcca gcagcctgat
     8341 ggggtcgatt gccgggattg ccgagctggt gaaagacagc gccaacaaac ggactcagcc
     8401 atgatggagt taatggtcgt tcatccacat attttctggc tcagtctcgg cggtttgctg
     8461 ctggcagccg agatgctggg cggaaatggt tatttgttgt ggagcggcgt ggcagcggtg
     8521 attaccggcc tggtggtctg gctggtgccg ctgggttggg agtggcaagg ggtaatgttt
     8581 gccatcctga cgctgctcgc cgcctggctg tggtggaaat ggttgtcgcg gcgggtgcgc
     8641 gaacaaaagc acagcgatag tcatttaaac cagcgcgggc agcagctgat tggccgacgt
     8701 tttgtgctgg aatctccgct ggtcaacggg cgcggtcata tgcgcgtcgg tgacagttca
     8761 tggcctgtca gcgccagcga ggatctcggt gcaggtacgc atgttgaagt cattgcgata
     8821 gaagggataa ccctacatat ccgagccgtc tcgtcttaat caccctgccc gatgatgaca
     8881 gcagccggag agattttcga taatcgggca gtcggcgctg tcatcgccag ggcaggcatt
     8941 cgccagtgcc agcagctggt cgcgcatgga ttgcagctcc tcaatgtgtc gttcgatctc
     9001 cgccaccttc tccagcgtgc gccgtttgac gtcggcgctg tgccgctgcg ggtcgttaaa
     9061 cagattcacc agctcgccgc tctcttccag gttaaagccc acctgccgtg cctggcgcag
     9121 taaggtcagt tcgttgagat gctgctgcgt gtaggtgcga taaccgtttt cgctgcgcat
     9181 cggcggcgtc accagcccct tctcttcata gaagcgaatg gctttgctgg tcaggccggt
     9241 aatttttgct acatcgctga tgttcatcgt tcgcgcaacg cctcctgtgc tttgttaaag
     9301 ggtttcaaca gatattcaag cacgtttttt tgccagtgcg aatatcgacc gccaccacaa
     9361 taatacagga agtactgcgc acagagagat gttatacggt tttattgcgc ttcatgacca
     9421 ttgccacaat aaggctgagt aagagtgagc caataatcca tatcaacgca cggctaccct
     9481 gggaccacag actgtagata aagccaacga tcaccaacaa catcaccaac gtaccaacga
     9541 taagaatcgg caacgaggcg tgaatatcat gacgcaggcg gatcgccacc acaaacaccg
     9601 ccaggtagca aatcaaaaag gtggcgctgg caacgctggc gagtgagcct aaattcagtg
     9661 ccgccgtcat cagcataatc aacaccacga caataatgtt gccccaggta ctctgccgcc
     9721 acagggattt attcattagc ttcggcagtt cgcgttcgct gcccatgttg tccatgatgt
     9781 taaacacggc gaacaggttc gcgttaatgg ctgaagccgt cgccagtaaa gcgccgatga
     9841 cgacgatcac ataacccaca tgcccgagca gcggagaagc agcctgcgct acggcggtat
     9901 cggcatattt ttctaactct aatgccgata catcgctaag caaaaccagt gccagcgaga
     9961 tataaagcaa cgtggtaacg ccaatcgcca ccagaaacgc ccgtggcata atgacctgcg
    10021 gatctttcac tttatccgcc gcgttcgcca tcatgccaaa gcccgcatag gcaaggaaag
    10081 ttatcccaat acaggagaag aacgcaccgg agctgggggg cgcagagacg gaaatatgcg
    10141 ccggttgcag cgaccagaca ccggcaataa tcagcaataa caggatcatc attttaatgc
    10201 cgacgaggat cacttccagc cgccctaccg catggttgct taaggagttg aaaagcgtca
    10261 tcaccgcaat gatccccaac gcgtagagca aaataaggtg ctcctcctgg ctgccttcat
    10321 gcaaaaactg cacggcataa gcgccaaaag cacgggcgac catggcgatg ctcaccgcca
    10381 gcgtcaacag gtacagtaac gagagcgcca gcgaaaagac gccgttgcct aatccgcgac
    10441 gaaagaagtc gataatgccg ccattgctgg gatagctcgc ccccagacgc gcataggcat
    10501 aaccggaaaa catcgccaca ataccgccaa aagcaaaggc gacccaggtc gaggcttcca
    10561 ttagcaatgc agcctgcccc agcagcgcga agatccccgc ccccaccatt gccccaatgc
    10621 cgatggaaac gacgttccat agaccgagag gtttgttacc gttattacct tccgtgttca
    10681 tcatgatcag cccttaaaca cgttatagcc gagttgctta gcgaccgatg ccaccatttt
    10741 ttgaccgcga acactgttgc catcttcgtc cagcggtggt gagaacgcgg caattcccat
    10801 cactccaggg acgaccgcca gaataccgcc acctacaccg cttttgcccg gtaaaccaac
    10861 acgatacgcc cagtcaccgg agcgaccata cagcccttcc atcatcattt cggccagaat
    10921 gtacggcacg ttgtcggcct gaagaacgcg tttatgcgtc aacggattca caccacctgc
    10981 cgccagcgtc gcgccaagcg ttgccagttc aatagtattg aggagcgtgg agcactgacg
    11041 ggtatacacg tcacaggctt ccattgcatc acaatagaga tatccggcgg agtacagcag
    11101 ccaggctatg gcccggttat ggaagttggt tgtttgttcc gactggttga cttcgtcaga
    11161 gagcgctacc tgctcgccag ccagttgctg ttggatatgt aaaattcgct gccagcgttg
    11221 ttcaacattt tcagcgttaa tcaggctggt ggtggcaata gcgccagcat ttaccagtgg
    11281 cgaaagcggt ttgccgccat gcaactctaa ggcgataact gagttaaagg gcaatccggt
    11341 cgggtcagcg ccaattttgt cctgtaccgc ctgcgggccg acatcttcta acgcaagggc
    11401 taacgtacag actttcgaga tggattccag tgcaaagcgg taatcactgt cacccgcact
    11461 atagacgttg ccatcgcagg tcacgatagc cactgccgcc agttgacctg gtacattcgc
    11521 cagaaaggga atgtaatcgg cattttgtcc gccgttaagt gagtgaaatt gggtgtaagc
    11581 ctgatccact gcctgctgta atttgtttgc atctaacatc ttttgttaac tcctttttat
    11641 agatgcggga ggtaattcct caccccggtg ccgattttca ggcatcctga tttaacttag
    11701 cacccgcaac ttaactacag gaaaacaaag agataaatgt ctaatcctga tgcaaatcga
    11761 gccgattttt taatctttac ggacttttac ccgcctggtt tattaatttc ttgaccttcc
    11821 ccttgctgga aggtttaacc tttatcacag ccagtcaaaa ctgtcttaaa ggagtgtttt
    11881 atgtcacaaa ctatcgacct gaccctggac ggcctgtcct gcggtcactg cgttaaacgc
    11941 gtgaaagaaa gtcttgaaca gcgtccggat gttgagcagg cggatgtgtc tatcactgaa
    12001 gcgcacgtta ccgggactgc cagtgcagaa cagctgatcg aaaccatcaa acaagcgggt
    12061 tatgacgcat ctgtaagcca cccaaaggct aaaccgctgg cggagtcatc aatcccgtcg
    12121 gaagcactga cagcggtttc tgaggcgctt ccggcagcga ccgccgatga cgatgacagc
    12181 cagcagttgc tgctgagcgg catgagctgc gccagctgtg tcacccgcgt acaaaatgcg
    12241 ctgcaaagcg taccgggcgt cactcaggca cgggtaaacc tggcggagcg tactgcgctg
    12301 gtgatgggca gtgcctcccc acaagattta gtgcaggcgg tggaaaaagc gggctacggc
    12361 gcggaagcga ttgaagatga cgctaaacgc cgcgagcgcc agcaagaaac cgccgtcgct
    12421 acgatgaagc gcttccgctg gcaggcaatt gtcgcactgg cggtgggtat cccggtgatg
    12481 gtctggggga tgatcggcga taacatgatg gtcaccgctg acaaccgcag cctgtggttg
    12541 gttatcggcc tgataaccct ggcagtgatg gttttcgccg gcggccattt ttaccgcagt
    12601 gcatggaaaa gcctgctgaa cggtgcggcg acgatggata cgctggtggc gctgggtact
    12661 ggcgtggcgt ggctctattc gatgagcgtc aacctgtggc cgcagtggtt cccgatggaa
    12721 gcgcgacatc tttattacga agccagcgcg atgattatcg gtctgatcaa tctcggccat
    12781 atgctggaag cgcgcgcacg ccagcgttct tctaaggcgc tggaaaagtt actcgattta
    12841 accccgccga cggcacgcct ggttactgac gaaggtgaaa aaagcgtgcc tctggcagaa
    12901 gtgcagccag gtatgttgct gcgcctgacg accggcgatc gcgtgccggt agatggcgag
    12961 attacccagg gcgaagcatg gctggatgaa gcgatgctga cgggcgaacc aatcccgcag
    13021 caaaaaggcg aaggcgatag cgtccatgcc gggacagtgg tacaggacgg cagtgtgctg
    13081 tttcgtgcca gtgcggttgg cagccatact acgctgtcac gaatcattcg catggtgcgc
    13141 caggcccaga gcagcaagcc agaaatcggt cagctggcgg ataaaatctc agccgtattt
    13201 gtgccggtag tggtggttat tgcgcttgtc agtgcggcaa tctggtattt ctttggtccg
    13261 gcaccgcaga ttgtctatac cctggtgatt gccaccacgg tactgattat tgcctgtccg
    13321 tgtgcgctgg ggctggcgac gccgatgtcg attatttccg gcgtcgggcg ggcggctgag
    13381 tttggcgtgc tggtgcggga cgctgacgcg ctgcaacgcg ccagtacact cgacactgta
    13441 gtgttcgata aaaccgggac gctgactgaa gggaagccgc aggttgtcgc agtgaaaaca
    13501 tttgctgatg ttgatgaagc gcaggcattg cgtctggcgg cggcactgga gcaaggttcc
    13561 agccatccgc tggcacgagc gatcctcgat aaagcaggtg atatgcagct accgcaggtc
    13621 aacggtttcc gcacattgcg cgggctgggc gtgagcggtg aagctgaagg tcatgcgtta
    13681 ttgctgggca atcaggcgct gttaaatgag caacaggttg gtaccaaagc tatcgaagcg
    13741 gagattactg ctcaggcatc gcaaggggca acgcctgtgc tgctggcggt tgacgggaaa
    13801 gcggtagccc tgctggcagt acgcgatccg ttgcgtagtg atagcgtggc ggcgctgcaa
    13861 cgcctgcata aagcgggata tcgtctggtg atgttgaccg gggataaccc aaccaccgcc
    13921 aatgcgatcg ccaaagaagc agggattgat gaggtgatcg ccggggtgct gccggacggt
    13981 aaagccgaag cgatcaaaca tctgcaaagt gaaggacgtc aggtggcaat ggtgggcgac
    14041 ggcattaacg acgcgccagc gctggctcag gcggatgtcg gcattgcgat gggtggcggc
    14101 agtgatgttg ccattgaaac cgcggcgatt accctgatgc gccatagcct gatgggcgtt
    14161 gcggatgcgc tcgctatttc ccgcgcaacg ctgcacaaca tgaagcagaa cctgctcggt
    14221 gcgtttatct acaacagtat cggtattccg gtcgccgccg gtattttgtg gccgttcact
    14281 ggaacactgc ttaacccggt agttgccgga gcggcaatgg cgctctcgtc gattaccgta
    14341 gtgagtaacg ccaaccggtt gctgcggttt aaaccgaagg aataagtaca tcattgcgga
    14401 tgcgctgctt tagggtggcg catttggcat cgacgcatga ctgccggatg cggcgtaaac
    14461 gccttatccg gcctacggtt caggcacagg tttgtaggcc tgataagacg cgtaagcgtc
    14521 gcatcaggca atggtgctcg gatgccggat gcggcgtgaa cgccttatcc ggcctacgag
    14581 atgaagcgat gttttggcct tacgcgacct tttttgcacg ctcttcacgg cgtgccaaat
    14641 attcagccac tgtttcaatc cgtcccaatt cttcctgggt gcgcatgttg ttttcaactt
    14701 cccaaagatc aaccgccgcc tggaggttta gccaaaaatc gactgtggta tcaaaaactt
    14761 tcgccagacg aaatgccatc tcagtagtga gtttacgatt gttattgatc agtgcactga
    14821 cgctattacg atgaacatgc agcaactctg ctaactcatt gattttcaaa tcgagcggtt
    14881 ccagatattc atagagaaga atatctccgg gtgtcgtcgg ttttcttgtt gcctgtttca
    14941 tggtttttaa ctgttgcttc cttgtgaata gcgatgcaag aacatactga atcatacaaa
    15001 cacattaaac aagtctccaa ctccatttgc gccatccctc accgcgcgct agcatgatat
    15061 ttcacaaagg gaggtcgtat ggatctgttg taccgggtaa aaacgctttg ggccgcgctg
    15121 cgcggtaatc attacacctg gcctgccatc gatatcaccc tccccggcaa tcgccatttt
    15181 catctgattg gcagtattca tatgggtagc cacgatatgg ctcccctgcc cacccgtttg
    15241 ctcaaaaagc tcaaaaacgc cgatgcgctg atcgtcgagg cggatgtttc caccagcgat
    15301 acgccttttg ctaatttgcc tgcctgcgag gcgctggaag agcgcattag cgaggagcaa
    15361 ctccaaaacc tgcagcacat tagccaggag atgggcattt ctccctcact cttttctacc
    15421 caaccgctgt ggcaaatcgc gatggttctt caggcgacgc aggcacaaaa actggggctg
    15481 cgggcagaat acggtatcga ttaccagcta ttgcaggcgg cgaagcaaca acataaaccc
    15541 gtgattgaac tggaaggggc tgaaaaccag attgccatgt tgctccagct ccctgacaaa
    15601 ggactggcgc tgctggacga tacgctgacc cactggcata ccaacgcacg gttgctgcaa
    15661 caaatgatga gctggtggct gaatgcaccg ccgcaaaata atgatataac gctgcccaat
    15721 acgttcagtc agtcgctgta cgatgtgctg atgcatcagc gaaatctcgc ctggcgggat
    15781 aaattacgcg ccatgccgcc ggggcgatat gtggtcgcgg tcggtgcact acacctgtat
    15841 ggagaaggga atttgccgca aatgttgcgc taaaaaaatg gccaatatcg ctattggccc
    15901 gtcaaagagg aatttcattt ttttattatt atgccgtcac tttaagcgac ggtgtaactc
    15961 gattgtcgct caatctcacc atcctgccaa tactcttagg caagatgact cttttttttg
    16021 gaccgccatc aggcgtatgc ttgcttcgtt tttttgttta aggcaggaaa attaccatga
    16081 cacccgcagt taaattactc gaaaaaaaca agatttcgtt tcaaatccat acctacgagc
    16141 acgatccggc tgaaaccaat tttggcgatg aagtcgtcaa aaaattaggt ttgaatccgg
    16201 atcaggtcta caaaacgctg ctggtggcag tgaacggtga tatgaaacac cttgccgtgg
    16261 ccgttacgcc ggtcgcaggt caactggatc ttaaaaaagt agcaaaagcg ctgggtgcca
    16321 agaaagttga gatggccgat ccgatggtcg cgcagcgttc gacgggatac ctggttgggg
    16381 ggattagccc actggggcag aaaaaacgtc tgccaacgat tatcgacgcc cccgcacaag
    16441 aatttgccac tatttatgtt tccggcggca agcgcggact ggatatcgaa ctggcggcag
    16501 gcgatctggc aaagatcctc gatgccaaat ttgctgatat cgcccgccgc gattaagcat
    16561 tgtgccggat gcaaacatcc ggcactttcg gattactgcc agctcacctc acctttcggt
    16621 tcataaacac tcacatccag cggcgagctt ttctggatat acgctttcag cacttcggca
    16681 tcaataaagc cggtattcac atagcccggt ttgttatcaa ggcgcggata tccatcaccg
    16741 ccggtggcat tgaagtttaa tgtcgccata cggtaagttt tcgccggatc gaccggttcg
    16801 cctttgattt taaggtcgtt cagtttgccg tctttcgcca caaagctaac gttggcaaat
    16861 tgcgggtagg cacctgaatc tggcttcatc tgcgcgacgg cggtcaggta atcaatcacc
    16921 tctttaccgg tcatgtcggc atacaccacc acattgccga atggctgcac tttcagcacg
    16981 tttttatagc tgatatcgcc tacttcgata gaatcacgaa ttccgcctcc gctcatcacc
    17041 gcaaagtcgg caccagtgcg atccatttgg gctgccagaa tcaaccgccc catattggtc
    17101 tgtacaaaac gcactttgtc acgatcgcct tccagacgac cattggtttc gcctattttc
    17161 acttccagct gcgctttgcc tttgttctgg aacggtgata acagcgagat catttgctgg
    17221 ttttcagcga tttcaggagt gtaaagcacg cgctcgcttt tcccgtcttc ccaggtcact
    17281 ttcttcttca ggttcaccgg aatcagctgg tagttaacca ttttcatttc gccattacga
    17341 aactcaaaat cagcccgtcc cacgtatttg ccccactcat gcgcctgcac aatccagatg
    17401 ccgttttgtt gatctggttt gcatggcgta cccggcacgt aatcgacctg ttttttgttt
    17461 tctgccgcca tgcagaccgg atcttgcgag tgaccaccga cgatcatcgc cagcgatccg
    17521 gcaggcagcg cgcgtgccat ctccacatcg cccggtgcgt tagagccgtg ctcaccatta
    17581 tcgtaatgcc ccatatgggt cgccgcgata ataatgtctg gcttttctgt ctgttgcagc
    17641 tcctgaatca ccagcttcgc ttcatcggcg ggcttacgaa attcgatatc agtgaagtat
    17701 tccgggttac caatttttgc tgtgtcatcg gttgtcagcc caataacggc aattttcaga
    17761 tcctgacgct taaacagcgc ccacggttta aacaggcgct cgccagtact tttctggtag
    17821 atattcgcgg aaagcaacgg gaacttggcc cacttttcct gctggcgtaa tacggtgagc
    17881 ggattatcaa attcatgatt accgatcgcc atcgcgtcat agcccaccag attcataccg
    17941 cgaaaatcag gttcggcatc ctgtaagtca gactcgggca cgccagtgtt aatgtcgcca
    18001 ccggaaagta gcagcacgct accgccttca gccgcaacct ctttgcggat accatccacc
    18061 agcgtttttt gcgccgccag accatattcg ccatattcat tgcgccaaaa atgcccatga
    18121 tgatcattgg tatgcagaac tgtaattttg taggttttat cctgctcata cgccagagca
    18181 gtttcactcg ccagtgtaaa tgtggttaac agcgctaacg ccacgccccg ctgcaataat
    18241 ttcatacttc tctccctgac ctgatttcaa cgtgttgaaa aatagtatga cgcgacatca
    18301 tagacaagtc tgcgtccggt gaagataaat ctgcatccag attagaaatt ctgtattcgg
    18361 cgttgagact tccttcagac gacgcataca ggtatgttag tctggtaata atcacaaata
    18421 agatcattct ttacatcgca accctgaaaa agtgactttc ctatggcaat gagtgaacaa
    18481 ccccagcctg tggcgggcgc ggctgcgtca acgaccaagg cccgaacatc gtttggtatt
    18541 ttaggtgcta tcagcctctc acatctgctg aacgacatga tccaatcgct gattctggcg
    18601 atttatccgc tgcttcagtc agaattttct ctgacattta tgcagattgg catgataacc
    18661 ctcaccttcc agctcgcctc ttcgctactg caaccagtgg tcggctactg gaccgataaa
    18721 tatccgatgc catggtcgtt gccaattggc atgtgcttta ccttaagcgg tctggtgctg
    18781 cttgcgctgg cgggcagttt tggcgcagtt ctgctggcgg cggcgctggt cggtaccggt
    18841 tcatcggtct ttcatccgga atcttctcgc gtggcccgta tggcttccgg cgggcggcat
    18901 ggcctggcgc aatctatctt tcaggtcggc ggcaactttg gcagttccct gggacccttg
    18961 ctggcggcgg tgattatcgc gccttatggc aaaggcaacg ttgcctggtt tgtgcttgcg
    19021 gcactgctgg cgatcgtggt gttggcgcaa atcagccgtt ggtactcggc acagcaccga
    19081 atgaataaag gaaaacccaa agcgacgatt atcaatccac tgccgcgcaa taaagttgta
    19141 ctggcggtca gcattctgtt aatcctcatt ttctcgaaat atttctatat ggcgagcatc
    19201 agcagctatt acacctttta tctgatgcaa aaattcggat tatctatcca gaatgctcag
    19261 cttcatctgt ttgccttcct gtttgccgtt gcggcaggta cggtgatcgg cgggcctgta
    19321 ggggataaaa ttgggcggaa atatgtgatt tggggctcta tcctcggcgt tgcgccgttt
    19381 acgctgattt taccctacgc cagcctgcac tggacggggg ttttaacggt gattattgga
    19441 tttatcctcg cttcggcatt ctctgccatt ctggtctacg ctcaggagct gcttccagga
    19501 cgtatcggta tggtttctgg actctttttc ggttttgctt ttggcatggg aggtctggga
    19561 gcggcagttc tggggcttat cgccgatcac accagcatcg agttagtcta taaaatctgt
    19621 gctttcctgc cactattggg gatgttgacc atattcctgc ctgataaccg gcataaagac
    19681 tgatttcatt gcagccaaag gcaaactttg gctgcatcgt tttacagtcg ccataagcct
    19741 ttcctctgtt aaaccgcctt ctgttttccg atccgtgctt tttttgcagc taattccatt
    19801 tttctgcaaa attcaataat tattcatgaa catcatcaat gaaattgtca taaactatta
    19861 cctgtaattt tggttttccc ggccaaaaat ggacaataac caccaggaaa aggagacgga
    19921 atgcatcacg ccaccccgct tatcaccacc attgttggcg gccttgtgct cgcctttatc
    19981 ctcggcatgc tggccaataa actacgtatt tctcctctgg tgggatatct gttagcgggt
    20041 gtgctggcag gaccattcac tccgggcttt gttgccgata ccaagcttgc cccggaactg
    20101 gctgaactgg gcgtcattct gttgatgttt ggcgtcggtt tgcacttttc gctgaaggat
    20161 ttgatggcgg taaaggccat cgccattccc ggtgcgatcg cccagatagc cgtggcgacg
    20221 ctgctgggta tggcgctctc tgccgtgctg ggctggtcgt taatgaccgg tatcgtgttc
    20281 ggtttatgtc tttccaccgc cagtaccgtg gtgttactgc gcgcacttga agaacggcaa
    20341 ttaattgaca gtcagcgtgg gcaaatcgcc atcggttggt tgattgtgga agacctggta
    20401 atggttctga cgctggtgtt gctgcccgca gtggcaggaa tgatggaaca gggcgatgtg
    20461 ggctttgcca ctcttgcagt cgatatgggg atcaccatcg gcaaagtgat cgcatttatc
    20521 gccattatga tgctggtagg tcgccgtctg gtgccgtgga ttatggcacg cagcgcggca
    20581 accggttctc gcgagctgtt taccctgtcg gtgctggcgc tggcgttagg ggttgccttt
    20641 ggtgcggtag agctgtttga tgtctccttt gcactcggtg cgttctttgc cgggatggta
    20701 ctgaacgagt ctgaactgag tcaccgtgcc gcccacgata cgctgccatt gcgcgacgcg
    20761 tttgcggtgc tgttttttgt ctccgtcggg atgttgtttg atccgttaat tctgattcag
    20821 caaccgctgg cagtgctggc gacgctggcg attattctgt ttggtaagtc gttagccgca
    20881 tttttcctgg tgcgactgtt tggtcactcc caacgtacgg cattaaccat cgccgccagc
    20941 ctggcgcaga ttggtgagtt cgcgtttatc ctggcgggac tgggaatggc attgaattta
    21001 ctgccgcagg ccggacaaaa cctggtactg gcaggggcga tcctgtcgat tatgctcaac
    21061 ccggtactgt tcgcactact ggagaaatat ctggcgaaga ccgaaacgct ggaagagcag
    21121 acgctggaag aggcaatcga agaagagaag cagatcccag tggatatttg caaccatgcg
    21181 ctactggtgg gttacggtcg tgtaggcagc ctgctggggg agaaattgct cgcctctgat
    21241 attccgctgg tggtgattga gacgtcacga acccgtgttg atgagctgcg agagcgcggg
    21301 gtccgcgcag tattgggcaa tgcggcgaac gaagaaatta tgcaactggc gcatctggaa
    21361 tgtgcaaaat ggctgatcct gacgattccc aacggttatg aagcgggtga gattgtggca
    21421 tctgcccgcg cgaaaaatcc ggatattgag attattgccc gcgcccatta tgacgatgaa
    21481 gtggcgtata tcaccgaacg tggtgcgaat caggtagtga tgggcgagcg tgaaatcgcc
    21541 cgtaccatgc tggaactgct ggaaacgcca ccggcgggtg aggtggtgac ggggtaaacg
    21601 gtggttgccg gatgtaaaat atgaaaaata tgtaggcatg ataagacgcg ccagcgtcgc
    21661 atcaggcatc gagagccaaa tgccagatgc ggcgtgaacg ccttatctgg cctacgaacc
    21721 gacgataact taacgatccc agtaagactc ttccaggctg tcttcacgct ccggcaagcc
    21781 gcgcgttaaa cgaggtgaat gctggttcag tacctgatag ctcacacggt tagcatattt
    21841 acacacctgc gctaacgatg aataagttaa ccaggtgaat ttatgtttgc tggagtttgg
    21901 tacgttgcta cgatggtagc tgttggcggt aatgtcatgc agcaacgctg ccaatgcgcc
    21961 atcccccgct ccattagtgt tcatgatttt ttccggcccg cccatgtacg gcgcaatgtg
    22021 cgaatataca cgcagcggat tctggcaatc cttgtggcgc atggcgcggc taaactcata
    22081 ctggttgaat tccgctatag cgcccggcag cagcggatgc tgggttttac gtttcgcttc
    22141 gtcttcggta aagcccgcca tatacaagcc gattggcccg gcggtgcaca gcaccagatc
    22201 tacccagtcc agcgccttgt cagatgccaa caacggatcg ctttctccgg tcaacgcttc
    22261 ggcttcatct tcgttcatcg caaggataga gacgtgatct ttgaggaatt gctgccacca
    22321 ctgcggattc tcggcaatga caaacttggt gcccagcgtc agcaccaccg gtacgttata
    22381 tttcttcgcg tactcaatgg ctttcatggt tgcttccggc atgggttcac ccggcttgca
    22441 acgcaccaga tatgaggtga gaaccagtgc cgaggctccg gcaatcacat cttccggaat
    22501 gctttcagcc cgcagctggt tcatgtggcc tggactgata gcaaaggtac gttccccgga
    22561 ctcgccaatc agcgtaaagc aacgaccaat cgggccatcc acgccttgta gatagttaag
    22621 atcggtacgg ctggaagtgt tacacaggta acgataggca taactgccaa tttcaatatt
    22681 gctgcacatg acgcccagca gcaccgaacg gtcgtccgcg agcaccgagt agttgtgcat
    22741 ggtgttacca atggtgccac ccgcaaactg atgggtaatc aggtttttct gttttagttc
    22801 ctgataaagc gcttcggcta catcatcctc aatcaccagt gaatgcccgg cgcttaatcc
    22861 ataacgctca ataaattcat catccacttt cgcttcaata tcgaccagcg tttgatcgat
    22921 acccactacc caggcagcgc tggtttcgtt ttctggctgg aattgctgaa gcagcggatc
    22981 gcgtgcgttt acggggaagt aatgtttgga tttacgttta ccgggaaatt tcatggttgt
    23041 ttttacgggt ggttaactga gcggcgaatg ttaacacaat ctgacgggag cgcgcgagac
    23101 gcagccagtt tcaatatcag caggcgggat cgcattttca tggcagtggt tccttacaat
    23161 gacgtaattt gaaaggagtt tttgtatgaa gccggaaaac aaactacctg ttctggacct
    23221 tatttctgct gaaatgaaga ccgttgtgaa tactcttcag ccggatttac cgccctggcc
    23281 cgcaacggga acgattgctg agcaacgaca gtattacacg cttgagcgcc gattctggaa
    23341 tgcgggcgct ccagaaatgg caaccagagc ttacatggtt ccaacaaaat atgggcaggt
    23401 ggaaacacgt ctcttttgtc cgcagccaga tagcccagcg acgctatttt atttgcatgg
    23461 aggcggtttt attctcggca atctcgatac ccacgatcgc atcatgcgcc tgctggcaag
    23521 ctacagccaa tgtacggtga ttggtattga ttacaccctt tcacctgaag cgcgttttcc
    23581 gcaagcgata gaggaaattg tggctgcttg ttgttatttc caccagcagg cggaggatta
    23641 tcaaatcaat atgtcccgca ttggctttgc cggtgattcc gcaggtgcca tgctggcgct
    23701 cgccagtgcg ttgtggttgc gtgataaaca gatcgattgc ggtaaagttg cgggcgtttt
    23761 gctgtggtat gggctttacg gattacggga ttccgtgact cgtcgtctgt tgggcggtgt
    23821 ctgggatggc ttaacgcaac aggatttgca gatgtacgaa gaggcatatt taagcaacga
    23881 cgcggaccgc gagtcgccgt attactgtct gtttaataat gatctcactc gcgaagttcc
    23941 gccctgtttt attgccgggg cggagttcga tccgctgctg gatgacagcc gtctgcttta
    24001 ccagacgtta gcggcgcatc agcagccctg tgagttcaaa ctctacccag gcacgctgca
    24061 cgcctttttg cattattcac ggatgatgaa aaccgccgac gaggctcttc gcgacggcgc
    24121 tcagttcttt accgctcagc tttagcgata cgcggcaaca agattagcca tcatttcgat
    24181 atgttccggc gtggcattaa gcgccggaat atattcatat tttttcccgc cggcaccgag
    24241 gaagacctca cggttttgct cggcaatctc ttccagcgtc tccagacaat ccgcagcaaa
    24301 gcccgggcac atcacctgaa tatgacctac gcctttttct ccgagcattt tcagcgtttc
    24361 gtcggtataa ggcatcagcc agggttcccg accaaagcgc gactgaaagg tcatcatcac
    24421 tttttccggt gccatcccca atgcggaagc cagttcacga gtcgttgtgc ggcaacgttg
    24481 cgggtaatca tcgccttcat ctgcataacg ctggggaatg ccatgataag agagcagtag
    24541 cagatccggt tcgccatgtt tggcaaaaga agcgcgtacg ctgttcgcca gtgcattaat
    24601 gtaatcgtgg ttatcggcgt aatcacgtat aaacgatatc cccggaatgc tacgtttgcg
    24661 cgccagaatg cgtgccagtt catcccatac cgcaccgacc gtagaacagg agaattgcgg
    24721 ataaagcggc agcaccacaa tatgatctac atgctctgcc aggagttcat ctacggcgct
    24781 ttccagtgat ggcgagccgt agctcattcc cagcgctacg ggcatctccg gtaaacgttg
    24841 tgccagcgcc tgctgttgct ggcggctgta aaccatcagc ggcgagccac cttccatcca
    24901 gacagaggca tacagcttcg ccacacgcgg cgagcgcagc ggcaaaatca cgccgcgcag
    24961 caatggccac cataacaacc gtgaggtatc aaccacgcgt ctgtcgctta aaaattgttt
    25021 cagatagcgt tttaccgctt caggtgtggg ggcatcgggc gtacccaggt ttgccagcag
    25081 gataccggtt ttagtctgac gcattaccgc ctcttatcga ttcaacttgt tgataattgt
    25141 agcggaaaag tgaggaagaa gaactaattg ctgtgagagg tcaaatcaga aaaaggaata
    25201 gcgcagattg aggtttttgt aaaaggccga atgaatatcc ggcctgagat tgctgataag
    25261 tttgcttgtg cgggcctgtt cccctcaccc taaccctctc cccgaggggg cgaggggact
    25321 gtccgtgcgc gctttcgaat tagccgagga ttttttccag atcagcgcga acttcagcaa
    25381 ccggcttggt gccgtcaact ttcgcgtatt tggtattacc cgcttctgct tctttggagt
    25441 agtagccgat cagcggtgct gtcatctgat ggtattcaac cagacgttta cgtacggtct
    25501 cttcctgatc atctttacgg gtagtcagtt cttcaccggt aacgtcgtct ttgccttcta
    25561 ctttcggcgg attgaattta acgtgataaa cacgaccaga cggcgcatga acgcggcgac
    25621 cgacgatacg gtcaacgatc agttcgtccg gtacgtcgaa ttccagaacg taatcaacat
    25681 tgatgcccgc ttctttcatc gcgtctgcct gcggaatggt acgcgggaag ccgtccaaca
    25741 ggaaaccatt acggcagtct tcctgagcaa tgcgctcttt aaccagcgcg atcaccagtt
    25801 cgtcggtgac cagtttgcca gcatccataa tgtcttttgc ttgtttaccc agctcggagc
    25861 cagatttgac cgcagcacgc agcatatcgc cagtggagat ttgcggaata ccatatttct
    25921 ccatgatgaa ctgagcctga gtccctttcc ccgcgcccgg agcgccaagc agaatgatac
    25981 gcattgcgaa aatcccctta aaatgtgtcg aattttttga aaaagcgata aacgatacca
    26041 ccaacaggcg attgcctcaa gaaaggcacc tggggctgaa acggttaatg gcgagataat
    26101 ttgcggaaag tgcagatgat gaaaagaaaa atgccggatg acacgaaggt catccggcat
    26161 tacatcagga aaccagcagc tggttcatac gacgaataaa caggttcgga tcttccagcg
    26221 tgccgcgttc tgccagcagc gcctgatcca gcagcagttc tacccactcg ctgaacttcg
    26281 cttcatcttc agtatctgcc gcacgtttca ccagtacgtg atccgggttc agttcgaaga
    26341 tgtatttcac ttctggcact ttctggcccg ccgcagcgaa cagtttcgcc atctgagtgc
    26401 tcatttcgtc cgcgtcggtc gaaacgatcg ctggcgtatc ggtcagacgg tgagtcagac
    26461 ggacatcttt cacgcgctcg ccgagcaggg ctttcacacg gtcgatgaac ggagtcagtg
    26521 ctttctccgc ttctttcgcg ctctcatcaa cttcgtcagc cagtttttca agcgactcgt
    26581 caactttaga caccgactgg aacggtttac cgtcgaactc agtcagatag ttcatcatcc
    26641 actcatcgat gcggtcggaa agcagcagaa cttcgatgcc tttcttacgc agcagttcca
    26701 agtgcgggct gctcttcgct gccgcatagc tgtctgcggt gatgtagtag attttctcct
    26761 gcccttcttt catgcgggaa acgtagtctt ccagagatac ggtctgcgca gaagaatcgg
    26821 tatgggtaga agcaaaacgc agcagtttgg cgatcgcttc ctggttagcg aaatcttccg
    26881 ccggaccttc tttcagtacc aggccaaact gttgccagaa ggtctggtat ttttccgcgt
    26941 cgtctttcgc cagtttttcc agcatttgca gcacacgctt ggtcagcgca ttgcgcaggt
    27001 tacgcgttac cgtgctgtcc tggaggattt cacgggaaac gttcagcggc agatcgctgg
    27061 agtcaatcag accacgcacg aagcgcagat agttcggcat gaactgttct gcgtcgtcca
    27121 tgatgaacac acgctgaaca tacagtttca ggccgtgttt atgatcgcgg ttccacatat
    27181 cccacggagc ctgggacggg atgtacagca ggctggtgta ctcctgctta ccttcaacac
    27241 ggttgtggct ccaggtcagc ggatcattaa agtcgtgggc gatgtgtttg tagaactctt
    27301 tgtactcttc atcggtgatt tccgacttgt tacgagtcca cagcgcctgc gctttgttga
    27361 ttttctccca ggagataacg gtttcgccgt ctttctcttc gcgtttttcg atctctaccg
    27421 gcagcgcgat atggtcggag tatttgctga tgatggaacg cacgcgccag tcatcgagga
    27481 actcgtcttc gccttcacgc agatgcaggg tgatttcagt accacgatct tctttggtga
    27541 tgtcggcaac ggtgtattca ccttcgccag ccgattccca gaagacgcca ttttctggtt
    27601 tttcgcctgc cgcgcgagta cgcacggtca ctttgtcggc cacgataaac gcagagtaga
    27661 aaccaacacc aaactgaccg atcagctggc tgtctttcgc ctggtcagaa cccagggatt
    27721 cgaggaatga tttggtaccg gatttagcga tagtccccag atggtcaatc acttcgtcgc
    27781 gggtcatccc cacgccgtta tcggagatgg tcagcgtacg cttgtcttta tcgaaagaga
    27841 cacgaacgcg tagttcgcca tcaccttcgt acaggtccgg gttagagagc gcacggaaac
    27901 gcagcttgtc cgccgcatcg gaggcgttag agataagctc acgcaggaag atttctttat
    27961 tggaatagag agaatggatc atcaggtgca gaagctgttt cacttctgac tgaaaaccac
    28021 gagtttcttg tcctttcatg taggtctacc tcaataatgc cattttaagg ttaaaaacag
    28081 gatgtgggag agatggggac aagggagaat aatttcaagc gagagcaggt gatcctgctc
    28141 tcgtttgctt aaaaacgaat cttatgacgc ccggcaaggg agtgtgacaa cgtggtgccg
    28201 tcgaccattt ccagctcgcc gccaaccgga acgccatgag cgattcggct ggcttccacg
    28261 tcatattgcg cgcaaagctc ggcaatgtag ttagcggtag cttcaccttc aaccgtgggg
    28321 ttggtggcga ggatcacttc agtgattttt tcctctgcca gacgctgttc cagacgatca
    28381 agcccgatat catccggacc gatgccgtcc agcggtgaca gatgccccat caacacaaaa
    28441 taacgacctg aaaactgccc cgtctgctca atggcgtaga tgtccgccgg actctccacc
    28501 acgcagattt gaccgttttc ctgacgacgc ggattcgaac agatgttaca gacttcctgt
    28561 tcggtgaaag tgcggcaatc ggcgcagtgg ccgatttccg acatcgcccg ggtgagcgcc
    28621 tgcgccagac gcatcccgcc gctacgatcg cgctgaagca gcgtgaacgc catacgctgc
    28681 gccgacttcg ggccaacgcc cggcagacag cgcagtgctt ccataagctg tgttaacagc
    28741 gggctggttt gcatcagaac ggcatcttaa agccaggcgg cagctgcatt ccggaggata
    28801 cagaggccat tttttctttc tgcgtttctt caatacgacg tgctgcgtcg ttgaatgctg
    28861 cagccaccag gtcttccagc atctctttgt cgtcttccag caggctcggg tcgatctcta
    28921 cgcgacggca gttgtgtgca ccgttgatgg tcacttttac cagacctgcg ccagattcgc
    28981 cggtgacttc cagctgcgcg atctcttcct gcattttctg cattttttct tgcatctgct
    29041 gggcttgctt catcaggtta cccagaccgc ctttaccaaa cataggtttc tctctcaatc
    29101 acgttaagga tgacgaacgt aagctgtgct tacgatcaaa tggggcggat actttcttca
    29161 tccagctccg catcgaagaa ccgacgcagg gtctgaatat tattatccgc aataatggac
    29221 tcgcgcgcct gcgcaagttt ttcttcgtat atcgcctgac gccactccag cggcgtacgc
    29281 accgcgggat tatcatcttc aacgatagtc agttcaaccg ttgaaccttt taacatgctc
    29341 aacgcttcag ccagtttttg ctgtgcaccg cggttgttca aatgccgctg agaggagcgc
    29401 aaatgcagac atactgcgtt gtcgctctcc tctttccagg catttaacgc cacctgttcg
    29461 accagttttg gtagcgaaag ttggctcacc tgtgccgccc acgggtcgcg ctcaatggct
    29521 tctgccgcta gcttcgccgc cagttccggc gttttttcat gttccagcgc ttttttcagc
    29581 gccttcggcg tggcgaccac ttctttttgc tgcatcaccg gagtggtcgc cttccagcga
    29641 tacgcttctt ttttggctgg cgctttttcc agcgccgatg gcaccggacg cgcctgaacg
    29701 cgatcggtga ccgaagccag tctttccagc gcagcgttat tcaccggccg cgcgcgggta
    29761 gcggctgccg gttcactctt ttttgctttg gttgctccct gcacgcgctg caactgctgg
    29821 cgcgccgcca gcacctggct ggtggtttcc gggagcggta cagtcggtgc ctgctgcggc
    29881 gctgattgcg gttgcggcgg cacctgggtt ggcgtcatta ctgccgttgg cgcgacgggt
    29941 gcaaaggact gtcgtggcac ttctggctca ggcagcggca tacgcggatg gaatgccagc
    30001 gcgcgcagca gcgtcatctc aacgcccatg cgacggtccg gcgcatacgg taattctttg
    30061 cgaccaatca acagcgtctg atagtaaagc tgaatatccg tcggcggtat ggtgcgcgcc
    30121 agttcacgca tccgcagctc gatggcggcc atgtcgttgc caagtgcagc aggcgaaagt
    30181 tgtaccatcg caatacgatg caacaggccg agcatttcca ccagcaacgc ttcccactcg
    30241 ataccacggg cagcggcttc attaatcagc gccattacgc gctcgccgtt ggcctcgacc
    30301 atcgcttcaa ccagcgacag cgcctgatcg tcgtcaagcg tacccagcat cgcactgacc
    30361 gcctgggttg aaacctggcc gtcaccgctg gcaatcgcct ggtcggtcag acttaaggca
    30421 tctcgcaggc tgccttcagc ggcgcgtgcc agcaattgca gcgcccgcgg ctcgtgagcg
    30481 atatgttctt cgttgaggat gtgctcaagc tgatggcgaa tttgctcgac atccagcgcc
    30541 ttgagatgaa attgcagaca gcgtgacaaa atcgtcaccg gcaatttctg tggatcggtc
    30601 gtcgccagca gaaacttaac gtgctccggc ggctcttcaa gggtttttaa cagtgcgtta
    30661 aagctgtggc gcgacagcat atgcacttcg tcgatcagat aaactttgaa acgaccacgc
    30721 gccggagcgt actggacgtt atccagcagg tcgcgggtat cttcaacttt ggtgcgcgag
    30781 gcggcgtcga tttcaatcag atcgacaaag cgcccctgct cgatttcacg acagttatcg
    30841 cacacgccgc acggcgtcgc ggtaatgccg gtttcgcagt ttagcccctt cgccagcagt
    30901 cgggcgatag aggtttttcc gacgccacgg gtgccggaaa aaagataagc atgatgaata
    30961 cgccctaacg acaagccgtt cgccagtgcg gtcagcacat gttcctggcc gacgacgtca
    31021 gcaaaggttt gtgggcgcca ttttcgggct aagacctgat aactcattgg caggctctga
    31081 aacgctggaa ggtggattca cgaaggggta atgctaacac agccccgtca gaacggcgag
    31141 gctgaatgca catcttgtgc tgtccgtagc gtgggcagca caagactggc gataattaat
    31201 ggcccgggaa cgggacaagg ctgtagctgg taatgccctg tttttcgaga cgctgttcgc
    31261 cgccgagatc gaacaggttg ataatgaacg cagcgtcagc cacttcacca cccagacgac
    31321 ggatcagttt aacggtcgct tcgatagtgc cgccggttgc cagcaggtcg tccaccacca
    31381 gaactttgtc gcccggtttg atggcatcaa cgtggatctc cagctgatcg gtgccgtatt
    31441 ccaggtcgta agtttcactg atggtttcac gcggcagttt gcccggttta cggaccggta
    31501 caaagccaac gcccagaccc agagctaccg gagcgccaaa caagaagcca cgcgcttcgg
    31561 tgccgacaac tttggtaatg cccgcatttt tgtaacgctc aaccagcaag tcgatgctga
    31621 gagcgtaagc tttcgggtct tccagtaagc tggtgacatc gcggaaaaga atgccgggtt
    31681 ttgggtagtc ctgaatgctt ttgatgctat ttttgagata ctcaagctgc tgtgcagtcg
    31741 cggtcataag tgtatgcctg cttgttacgg tggtactcac ggcgcgtttt aaacgtatca
    31801 aaagtaacag ttgtttaacc tttgaccgcc tgcgcctgtg ctcgaaaacg ccagaatgta
    31861 ctggctgtac gcaataattg caactgcgat tgttgtgctt cagtgctttt cttgcttttc
    31921 atcaatcacc ggaattcgcc acatatagaa aagcaaacag gcgagaatta ccagcaacat
    31981 gatgcgcacc catggcatct ggacgaacca cagagaaatg gcaaacgtga gcaaaataag
    32041 caaaatcgcc cgcggtttga cgccgcgcgg catcgcatga tgtttctgcc agaaacgtag
    32101 atagctgcca aaccatgagc ggtacagcaa ccaggcgtga aagcgcgggg aagaacgggc
    32161 aaagcaccag gccgccagca ggataaacgg cgtcgtcggt aataccggta ataccacgcc
    32221 cagcgtaccc agcactaccg ccagccagcc aatgatgatt aaaatgattc gttgcatatt
    32281 gagtgttgtc agcttacaga gtggctactt tagcataaca attatcattt tcattgaggt
    32341 cttatcgtga aaaccgccct gctgctggaa aaactggaag gacagctcgc tacgctgcgt
    32401 cagcgttgtg ccccggtgtc acagttcgcc acgctaagtg ctcgtttcga caggcatctt
    32461 tttcagactc gtgcgacaac actacaggct tgtctcgacg aggcgggcga taatctggct
    32521 gcgcttcgtc atgcagttga gcagcaacag ctgccgcaag tggcctggct ggcggaacat
    32581 ctggcggcac aactggaagc catcgcgcgt gaagcctccg cctggtcatt gcgcgagtgg
    32641 gacagtgcac caccgaaaat tgcccgctgg cagcgtaaac gtattcagca tcaggatttt
    32701 gagcggcggc tacgtgagat ggttgccgaa cgcagagccc atctggcgcg ggtgaccgat
    32761 ctcgtggaac agcaaacgct gcatcgtgaa gtggaagcct atgaagcgcg cctggcacgc
    32821 tgccgccatg cgctggaaaa aatcgaaaac aggttagcgc gtttaacccg ctagcaatgg
    32881 agagaatatg tcactggaaa atgcccctga cgatgtcaaa ctggctgtcg atttgattgt
    32941 gctgctggag gaaaatcaga tccctgccag taccgtgctg cgcgcgctgg atattgtaaa
    33001 gcgtgattat gaaaagaaat taacgcgcga tgatgaggcg gaaaagtgag aaataaatgg
    33061 ggtcgctaaa tgtcccctaa ggttgcgggc aaacgcaaaa ctgcctgatg cgctacgctt
    33121 atcaggccta caccgctcct gcaatatatt gaattcttgc ggtttcgtag gccggataag
    33181 gcggtcacgc cgcatccggc atgaacaacg cgcactttgt tagcaatctc ggggcaacta
    33241 aatgttgccc cctttcgttt ttaccctacc gctggcgtcg ggtcatcgcc tttgtagtcg
    33301 cgttttactt ccgtcacctc atcgcccttc tcgttgtgca gatgcacttc aagctggtta
    33361 aaggcaatgt tgatgtcgtt ttcacggcac agctgatcga tagtacggtt cagctcatcg
    33421 acagtacgac tacggtcacg cagttcacgc acatacagac gcagctcatg atccaacgtg
    33481 ctggcaccaa atgccgtaaa gaagacttcc ggcattggtt cgtgcatcac ccttgggtgc
    33541 tcagtcgccg ccttcagtaa cactttacgc actttttcca gatcggagcc ataggccacg
    33601 ccgagacgga tcaccagacg cgtagtagtg tcagtcaacg accagttgat cagacgctcg
    33661 gtaacaaacg ctttgttcgg gatgatcact tctttgcgat cgaaatcggt aatcgttgtc
    33721 gcacgaatac ggatcttact taccgtcccc gagaagctac caatggttac cgtatcgcca
    33781 atacgcaccg gacgttcgaa tagaatgatc aaaccggaga cgaagttacc gaaaatttct
    33841 tgtaaaccaa aaccaagacc tacggataat gctgcggcca gccactggag tttatcccaa
    33901 gagacgccca gcgatccgaa caccgtcatc gcaccaacag caataatgat gtagttaagg
    33961 atggtagtaa tggcatacga cgcgccctgg cgcatattca gtcgcgagag caccagcact
    34021 tccagtaaac caggcaggtt gcgaatcaac gcccaggcca ccattgaggc gataatcgca
    34081 aacaacagac tgcccatggt gacgtttttc accaccgcag cgccagcttc agtgccgttg
    34141 taatgccaga gcgtgatgct gtcgagatag ctgaacacgg tgatcaaatc ggaccaaatt
    34201 gcccagaaca tgacaccgaa cagcgcaaac atcagcaaca tggtaatacg cagcgtctgc
    34261 tggttaactt gctccagtgc aatggtgggt tcttccggcg gttcagcacc ttctgcgccc
    34321 tctttcacca gattctgccg acgcgccagc gcacgacgcc aggcgatacg ccgcgccgct
    34381 acgcttaagc cacgcagtac cgtctggtac agcaggttcc agatgatcac cagataaacg
    34441 gtttcaatcc agcgtcctgc cagacgcagc gtagtgtaga agtagcctgt agcagtcagc
    34501 accatcagcg caatcgggat tatcgacagc acggtaatgg tgaccagtcg catggtgtgc
    34561 gactctttat cacgccagct ttcgcggcac atcggccata ccaggaaggc aatcagcagc
    34621 aggttgaaga aaatcatcgc ttgccccagc acatcatcca tcagatgcag cggggaaagt
    34681 tctgccacca cagaccagaa atggataggc agcaatgcga gactgatgcg gacaatttgc
    34741 cgacgccagt ggctggtctg ctgttccggc atgccgaagt gacgtacggc aacgccgttt
    34801 ttctccagta ccttccagca caggccaaac accagccaga atatcgccag ttttttgctg
    34861 aacgaccata gcagttcgct gatgttgagc tgcatggtca acagaatcag gccaaccgcg
    34921 agaataatca ggcacaccgg cagcgcacgg atcaggtcga taaggatcgc ttttggtgtg
    34981 ttgagctggc tgtcgttacg cagggaaccc acagcggaag ccagtttttg ttgatacgct
    35041 ttcagccagc ccagacgcca gtggatcagc ccggcaatca acagcagcgg caaaccagcg
    35101 aggaaagcga taaaaacggc gggccaggct ttttgccagt tcaccgtgat tttcatcgac
    35161 ttaaattcat ctttcaggct ttgcgggaac gctttgatcc agtcccagtc cattggacgg
    35221 ttactgttca cccaaaagat ttgctgagtc aggatggatt tcaggttttt cgacacactc
    35281 attaactgct gctggttgat ttgcaggtta atggccatca tcagctggtt acccaactgt
    35341 ttgttgagtt gatccagcaa ttcgcgacgc atatcaacca cttgcaataa cgcatcgtga
    35401 acttcgctgt tgacttcgtt ggtgtgacct tcttccagtt tgttgacgaa cgcatcgctc
    35461 tggaagagtg catcacgctg ctggttaact tcaaactgtt cgagacgcaa atccgcgatg
    35521 cggttggtca tgttttccag ttcatccgcc gagggcagcg tttgttgttg ctggtaaagg
    35581 atacgagaca acagcaggct gcccttcagg acggcaatct gctctttaat attgcgttcc
    35641 gattgcagcg cccgctccag ccagtttttg actttaatgt tttgctgcat caactgatta
    35701 ccgttttcag tcgcggtaat cagacgctga cttaactgct ggttaatttc cagttcctgc
    35761 ttcaccagcg gattagcctg aatacgcgcg gcttcatccg gggagacggc ttcctgcgcc
    35821 gttttttcgg ttaaagtcag gcgcttgctg tttaccgctt cttgcaacag ttgtaactgg
    35881 tgctccagac gagcgctgtt cgccgtcacg taatcacgtt gcttttgcaa ggtatcctgc
    35941 aagacggtgt tcccttccag gcttttacgc tgctggtcaa tctccgcatt cagcaacgcc
    36001 tgctgggcct gcattaacac tttctggctg ggacgtaagg ctgtctcgcc gacatcagtc
    36061 ccatccagac gactgcgaat ttgttgcagc tgctgcgaag cgttatacat cgcattttgc
    36121 acgcgttcgg gctgcgtctg taacgaaacc agctggctgt tataagacgc cagatcgttt
    36181 tgtgcgtttt gcaaatcgtc cagcgcctgg gcaacgcgag tttccagctg gcgcaacgac
    36241 agcgtgctca gaattttgcg cgtttcttcg tcgttatcga catcgctaag tgctgttaac
    36301 gccgcggtcg cctggcgcat tttttccggc gcttcagcga ctttttgccg tagctgaact
    36361 gtctcttctt ttatgcgatc gattttatcg agggtggcta atgtatctgt cagatcctgc
    36421 tgcaccagtt tgtcctgagc agaaagatct ttttgtttat ttagtgagtc aagttgcgcc
    36481 tgcaggtccg cttttgtcgg cagatcacca ttcgatgacg cccgcgcaaa cgccgtgttc
    36541 tggcataaca agacaaaaac aaaagcaata aatgctgaaa aaacaaaatg ccgtgatcgt
    36601 ttgtaatact ggaacatagt catgatgaat gaaggtttct gaacctgaag aacgacctga
    36661 aaaagtcaaa ccgcaagaat atcacgacgc agtgaaccag aatagcaacg acgaaaatgt
    36721 ccaggaaaaa tcctggagtc agattcaggg ttattcgtta gtggcaggat tacgaagcgt
    36781 ggggcacagg agatacatct ccagtaagat ggcaacgtaa tcgcgggctt cttttttaag
    36841 atcaaaagat tgcggggcaa agagccagtt ttccatcagg ccggaaatat agccgcgcat
    36901 aataattgct gcgcgacgcg tcattaaatc cgcaggcaac attttcgctt caatacaatg
    36961 ttttaacgtt tgttctatac ggtcataact ttccagacag agattacgtt gtgcctgttg
    37021 cacaacagcc atttctccga caaattcgca tttgtggaat ataatctcca tcaataatcg
    37081 acgccgttct tctgtcaccg tggattcaag aacatgaatt aatatctctc ttaatactga
    37141 gagtggatcg ccagggaatt ttgcctgata ctcaagctct agttcaccaa tattggattc
    37201 tgacagttcc cagatctcac tgaacaaatc cgacttgtct ttaaaatgcc agtagattgc
    37261 accgcgcgta acgccagctg cttttgcaat ctcgcccagc gaggtggatg ataccccctg
    37321 ctgtgagaaa agacgtagag ccacatcgag gatgtgttgg cgcgtttctt gcgcttcttg
    37381 tttggttttt cgtgccatat gttcgtgaat ttacaggcgt tagatttaca tacatttgtg
    37441 aatgtatgta ccatagcacg acgataatat aaacgcagca atgggtttat taacttttga
    37501 ccattgacca atttgaaatc ggacactcga ggtttacata tgaacaaaaa cagagggttt
    37561 acgcctctgg cggtcgttct gatgctctca ggcagcttag ccctaacagg atgtgacgac
    37621 aaacaggccc aacaaggtgg ccagcagatg cccgccgttg gcgtagtaac agtcaaaact
    37681 gaacctctgc agatcacaac cgagcttccg ggtcgcacca gtgcctaccg gatcgcagaa
    37741 gttcgtcctc aagttagcgg gattatcctg aagcgtaatt tcaaagaagg tagcgacatc
    37801 gaagcaggtg tctctctcta tcagattgat cctgcgacct atcaggcgac atacgacagt
    37861 gcgaaaggtg atctggcgaa agcccaggct gcagccaata tcgcgcaatt gacggtgaat
    37921 cgttatcaga aactgctcgg tactcagtac atcagtaagc aagagtacga tcaggctctg
    37981 gctgatgcgc aacaggcgaa tgctgcggta actgcggcga aagctgccgt tgaaactgcg
    38041 cggatcaatc tggcttacac caaagtcacc tctccgatta gcggtcgcat tggtaagtcg
    38101 aacgtgacgg aaggcgcatt ggtacagaac ggtcaggcga ctgcgctggc aaccgtgcag
    38161 caacttgatc cgatctacgt tgatgtgacc cagtccagca acgacttcct gcgcctgaaa
    38221 caggaactgg cgaatggcac gctgaaacaa gagaacggca aagccaaagt gtcactgatc
    38281 accagtgacg gcattaagtt cccgcaggac ggtacgctgg aattctctga cgttaccgtt
    38341 gatcagacca ctgggtctat caccctacgc gctatcttcc cgaacccgga tcacactctg
    38401 ctgccgggta tgttcgtgcg cgcacgtctg gaagaagggc ttaatccaaa cgctatttta
    38461 gtcccgcaac agggcgtaac ccgtacgccg cgtggcgatg ccaccgtact ggtagttggc
    38521 gcggatgaca aagtggaaac ccgtccgatc gttgcaagcc aggctattgg cgataagtgg
    38581 ctggtgacag aaggtctgaa agcaggcgat cgcgtagtaa taagtgggct gcagaaagtg
    38641 cgtcctggtg tccaggtaaa agcacaagaa gttaccgctg ataataacca gcaagccgca
    38701 agcggtgctc agcctgaaca gtccaagtct taacttaaac aggagccgtt aagacatgcc
    38761 taatttcttt atcgatcgcc cgatttttgc gtgggtgatc gccattatca tcatgttggc
    38821 aggggggctg gcgatcctca aactgccggt ggcgcaatat cctacgattg caccgccggc
    38881 agtaacgatc tccgcctcct accccggcgc tgatgcgaaa acagtgcagg acacggtgac
    38941 acaggttatc gaacagaata tgaacggtat cgataacctg atgtacatgt cctctaacag
    39001 tgactccacg ggtaccgtgc agatcaccct gacctttgag tctggtactg atgcggatat
    39061 cgcgcaggtt caggtgcaga acaaactgca gctggcgatg ccgttgctgc cgcaagaagt
    39121 tcagcagcaa ggggtgagcg ttgagaaatc atccagcagc ttcctgatgg ttgtcggcgt
    39181 tatcaacacc gatggcacca tgacgcagga ggatatctcc gactacgtgg cggcgaatat
    39241 gaaagatgcc atcagccgta cgtcgggcgt gggtgatgtt cagttgttcg gttcacagta
    39301 cgcgatgcgt atctggatga acccgaatga gctgaacaaa ttccagctaa cgccggttga
    39361 tgtcattacc gccatcaaag cgcagaacgc ccaggttgcg gcgggtcagc tcggtggtac
    39421 gccgccggtg aaaggccaac agcttaacgc ctctattatt gctcagacgc gtctgacctc
    39481 tactgaagag ttcggcaaaa tcctgctgaa agtgaatcag gatggttccc gcgtgctgct
    39541 gcgtgacgtc gcgaagattg agctgggtgg tgagaactac gacatcatcg cagagtttaa
    39601 cggccaaccg gcttccggtc tggggatcaa gctggcgacc ggtgcaaacg cgctggatac
    39661 cgctgcggca atccgtgctg aactggcgaa gatggaaccg ttcttcccgt cgggtctgaa
    39721 aattgtttac ccatacgaca ccacgccgtt cgtgaaaatc tctattcacg aagtggttaa
    39781 aacgctggtc gaagcgatca tcctcgtgtt cctggttatg tatctgttcc tgcagaactt
    39841 ccgcgcgacg ttgattccga ccattgccgt accggtggta ttgctcggga cctttgccgt
    39901 ccttgccgcc tttggcttct cgataaacac gctaacaatg ttcgggatgg tgctcgccat
    39961 cggcctgttg gtggatgacg ccatcgttgt ggtagaaaac gttgagcgtg ttatggcgga
    40021 agaaggtttg ccgccaaaag aagctacccg taagtcgatg gggcagattc agggcgctct
    40081 ggtcggtatc gcgatggtac tgtcggcggt attcgtaccg atggccttct ttggcggttc
    40141 tactggtgct atctatcgtc agttctctat taccattgtt tcagcaatgg cgctgtcggt
    40201 actggtggcg ttgatcctga ctccagctct ttgtgccacc atgctgaaac cgattgccaa
    40261 aggcgatcac ggggaaggta aaaaaggctt cttcggctgg tttaaccgca tgttcgagaa
    40321 gagcacgcac cactacaccg acagcgtagg cggtattctg cgcagtacgg ggcgttacct
    40381 ggtgctgtat ctgatcatcg tggtcggcat ggcctatctg ttcgtgcgtc tgccaagctc
    40441 cttcttgcca gatgaggacc agggcgtgtt tatgaccatg gttcagctgc cagcaggtgc
    40501 aacgcaggaa cgtacacaga aagtgctcaa tgaggtaacg cattactatc tgaccaaaga
    40561 aaagaacaac gttgagtcgg tgttcgccgt taacggcttc ggctttgcgg gacgtggtca
    40621 gaataccggt attgcgttcg tttccttgaa ggactgggcc gatcgtccgg gcgaagaaaa
    40681 caaagttgaa gcgattacca tgcgtgcaac acgcgctttc tcgcaaatca aagatgcgat
    40741 ggttttcgcc tttaacctgc ccgcaatcgt ggaactgggt actgcaaccg gctttgactt
    40801 tgagctgatt gaccaggctg gccttggtca cgaaaaactg actcaggcgc gtaaccagtt
    40861 gcttgcagaa gcagcgaagc accctgatat gttgaccagc gtacgtccaa acggtctgga
    40921 agataccccg cagtttaaga ttgatatcga ccaggaaaaa gcgcaggcgc tgggtgtttc
    40981 tatcaacgac attaacacca ctctgggcgc tgcatggggc ggcagctatg tgaacgactt
    41041 tatcgaccgc ggtcgtgtga agaaagttta tgtcatgtca gaagcgaaat accgtatgct
    41101 gccggatgat atcggcgact ggtatgttcg tgctgctgat ggtcagatgg tgccattctc
    41161 ggcgttctcc tcttctcgtt gggagtacgg ttcgccgcgt ctggaacgtt acaacggcct
    41221 gccatccatg gaaatcttag gccaggcggc accgggtaaa agtaccggtg aagcaatgga
    41281 gctgatggaa caactggcga gcaaactgcc taccggtgtt ggctatgact ggacggggat
    41341 gtcctatcag gaacgtctct ccggcaacca ggcaccttca ctgtacgcga tttcgttgat
    41401 tgtcgtgttc ctgtgtctgg cggcgctgta cgagagctgg tcgattccgt tctccgttat
    41461 gctggtcgtt ccgctggggg ttatcggtgc gttgctggct gccaccttcc gtggcctgac
    41521 caatgacgtt tacttccagg taggcctgct cacaaccatt gggttgtcgg cgaagaacgc
    41581 gatccttatc gtcgaattcg ccaaagactt gatggataaa gaaggtaaag gtctgattga
    41641 agcgacgctt gatgcggtgc ggatgcgttt acgtccgatc ctgatgacct cgctggcgtt
    41701 tatcctcggc gttatgccgc tggttatcag tactggtgct ggttccggcg cgcagaacgc
    41761 agtaggtacc ggtgtaatgg gcgggatggt gaccgcaacg gtactggcaa tcttcttcgt
    41821 tccggtattc tttgtggtgg ttcgccgccg ctttagccgc aagaatgaag atatcgagca
    41881 cagccatact gtcgatcatc attgatacaa cgtgtaatca ctaaggccgc gtaagcggcc
    41941 ttttttatgc ataacctacg aacattaagg agtaattgaa ccaccaactc aggatctcat
    42001 acgaaaacca gtattaacca cggataaaat tcataaaaaa tactgattgt tagttaattt
    42061 atattaagta gcgctaatag atttaataat ccataatcat ttagaggcta ttcttaatta
    42121 tttgcggtaa ttctttattc attcctcggt tattacgtca tattcagagc aatcctggta
    42181 ttagtgtcac caatttcatc tggcgataat cctgaaatgt tatgaatagt tcgagcaaac
    42241 tgcttttacc tgctgcgggt tagtgctagt atgaaaaagt gagtcctgtc ccgcttcctt
    42301 cctaattgta atttttcgta ataatgcgat gaaaacctgc aaagagtggc ttatagttaa
    42361 gctaacaaac gagagggcaa gtccaggtca gtaagttttt tccatcccga aaggtgtccg
    42421 ttagttcaac cgctaagaag gggacgcgtt atggatgaat actcacccaa aagacatgat
    42481 atcgcacagc ttaagtttct ctgtgaaacc ctgtatcatg actgccttgc aaaccttgaa
    42541 gaaagcaatc atggctgggt aaacgaccca acctcggcga tcaacctcca gttgaatgaa
    42601 ctgattgagc atattgcgac cttcgcactt aattacaaaa ttaagtataa tgaagacaat
    42661 aagctcattg agcagatcga cgaatatctg gatgacacct ttatgttgtt cagtagttat
    42721 ggtattaata tgcaggatct tcagaaatgg cggaagtcag gtaatcgact attccgttgt
    42781 tttgtcaatg cgacgaaaga gaatcctgcg agtttatctt gttagaatta ttacaaccat
    42841 aggtagaagt atgtccgaaa aacctttaac gaaaaccgat tatttaatgc gtttacgtcg
    42901 ttgccagaca attgacacgc tggagcgtgt tatcgagaaa aataaatacg aattatcaga
    42961 taatgaactg gcggtatttt actcagccgc agatcaccgc ctcgccgaat tgaccatgaa
    43021 taaactgtac gacaagatcc cttcctcagt atggaaattt attcgctaat aaataattcg
    43081 ctttcggagc tataaccggc tgtttattaa gaattttata ctttttcgcc atgaagacat
    43141 accctatgtg atctttatca cacagatgta atgggaacgt tctcttcact gacttttcgt
    43201 cttactgtgt tgccgcattt tcagcaaccg gaggtcagta atgagtacag aaaaagaaaa
    43261 gatgattgct ggtgagttgt atcgctcggc agatgagacg ttatctcgcg atcgcctgcg
    43321 cgctcgtcag cttattcacc gatacaatca ttccctggcg gaagagcaca cattacgcca
    43381 gcaaattctc gctgatctat tcggtcaggt gacagaggct tatattgagc caacgtttcg
    43441 ctgtgactat ggctataaca tttttctcgg taataatttt ttcgccaact tcgattgcgt
    43501 gatgcttgat gtctgcccta ttcgcatcgg tgataactgt atgttggcac caggcgttca
    43561 tatctacacg gcaacacatc ccatcgaccc tgtagcacgt aatagcggtg ctgaactggg
    43621 gaaacccgtc accatcggta ataacgtctg gattggcgga cgcgcggtca ttaaccctgg
    43681 tgtgaccatt ggtgataacg tcgtggtagc ctcaggtgca gttgtcacaa aagatgtccc
    43741 ggacaacgtt gtcgtgggcg gtaatccagc cagaataatt aaaaaattgt aatcggtttt
    43801 tcgcaactgt tatgcaaaat tgtggtagat ctgttacttc ccctctacta ttcccacgtt
    43861 aaaatagggt gttccctgga aagttgcaga taccacgaag gcaaacgatg accgaaatac
    43921 aacgcctgct gaccgaaacg attgagtctc tgaatacccg cgaaaaacgc gacaacaaac
    43981 cccgctttag tatcagtttt atccgtaaac atccggggct gtttatcggt atgtacgttg
    44041 ctttttttgc caccctggcg gtgatgttgc agtccgaaac gctgtcaggc tctgtctggc
    44101 tactggttgt attatttatc ctgcttaatg gtttcttctt tttcgatgtc tacccacgct
    44161 accgctatga agatatcgac gtgctggatt tccgcgtttg ctataacggc gaatggtaca
    44221 acacgcgctt tgtacctgcc gcgctggttg aagccatctt gaactctccg cgtgtcgcgg
    44281 atgttcataa ggaacaactg caaaaaatga tcgtccgtaa aggtgaactg tctttttacg
    44341 atatttttac cctcgctcgc gccgaatcaa catcttaagt tagggttaca taccaggcgt
    44401 aaagctctgc gcctggtcaa atgacaatga tcgtttccac ccatcacttc atgaaatacc
    44461 agctctacct ccttatctcc agccagcctt tttccacaat cagatatact ttccctacac
    44521 tgtgttaata aggatatgct ggtgagaaca cgacatctgg tcggccttat ttcgggagta
    44581 ctgattcttt cagtattgct gcctgtcggc ttaagcatct ggctggccca tcagcaggta
    44641 gaaacatcgt ttattgaaga gctggatacc tattcctccc gcgtcgctat tcgagccaat
    44701 aaggtggcga cacaagggaa agatgcgctg caggagctgg aaagatggca aggcgctgcc
    44761 tgtagcgaag cccatctcat ggaaatgcgt cgggtatctt acagttatcg ctatattcag
    44821 gaagtggctt atatcgataa caacgttccc cagtgttcgt ctctggagca tgaaagtccg
    44881 cccgatacct tccccgagcc aggtaaaatt tcgaaagatg gttatcgtgt ctggttaaca
    44941 tcgcataacg atttaggcat tatccgttac atggtcgcca tgggaacggc acattatgtc
    45001 gtcatgatcg accccgcttc ctttattgat gtcattccct atagctcatg gcaaattgat
    45061 gccgccatta ttggcaatgc ccataacgtt gtcataacca gcagcgatga aattgctcag
    45121 ggaattatta ccaggctaca aaaaacaccc ggtgagcata tcgaaaataa tggaatcatt
    45181 tacgatatcc tgcccttacc ggagatgaat atttcgatca tcacatgggc ttcaacgaaa
    45241 atgttgcaga aaggctggca tcggcaagtc tttatttggt taccgctcgg gttggtgatt
    45301 ggcctgctgg cagcgatgtt tgtgctgcgt attttgcgcc gtattcagtc accgcatcat
    45361 cggctgcagg atgctatcga aaatcgtgat atttgcgtgc actatcagcc gattgtctcc
    45421 ttagccaatg gcaaaattgt cggtgctgag gcactggcgc gctggccgca gacagacggt
    45481 agttggttgt caccagatag ttttattccg ctggcacagc aaacgggcct ttctgagcca
    45541 ttgacgctac tgattataag aagcgtcttt gaagatatgg gcgactggct gcgtcagcat
    45601 ccacagcagc atatttcgat caatcttgaa tcccccgtgc tcacctcgga aaaaatcccg
    45661 caattgctgc gtgacatgat caatcactat caggttaatc ccagacagat cgcgcttgaa
    45721 ctcactgaac gcgagtttgc cgatccgaaa accagcgccc cgataatttc tcgctaccgg
    45781 gaggcgggcc atgaaattta tcttgatgat tttggtacgg ggtattcaag tttaagttat
    45841 ttacaggatc tggatgtcga cattctgaag atcgataaat ctttcgttga tgcgctggaa
    45901 tataaaaatg tcacgccgca tatcatcgaa atggcaaaaa cactgaaact gaaaatggta
    45961 gcggagggaa tcgaaaccag taaacaagaa gagtggttac gccagcatgg cgtgcactac
    46021 ggtcagggct ggctctacag caaggcatta ccgaaagaag atttcttacg ctgggccgag
    46081 caacatttgt gaatttttgg gctgacggca cgccgcacag cccgtcacgc tacctattcg
    46141 tcgatgattg actcgaatcc gccatagatc attcgcttgc cgtcaaacgg catggactcg
    46201 ccgaactctt tcatccgtgg gtccgacatc atcttttgat tagcagcgtc gcggacctct
    46261 tttgaagggt attcaatcca gctaaagaca acctcttcat tctcttccgc tttcaccgcc
    46321 atacgaaaat cggtcacttt gccatccggt acatcgctgg cccagcattc gacaatacga
    46381 agcgcgccaa actctttaaa caatggcgca gccttagcgg ccatttcccg ataggcatcc
    46441 tttttatcgg caggaacggc aaccacaaaa ccatcaacat acttcatcag acatacctcc
    46501 gaagcgtact gcgcagccag acaattcttg cgacgtcagt tgtggttaaa gtttagccat
    46561 gttgggattt tttgacgaaa cggtgggagg cagaaatggg tgggggccct gccagctaca
    46621 tcccggcaca cgcgtcatct gccttggctg cttccttccg gacctgacct ggtaaacaga
    46681 gtagcgttgc gggagaacca acagagcccc cattgagagc gttgagaacc aacgcgcagg
    46741 cgcattatca ctgctgcccc ggctaattgc aacccatcgc gtgccagatg ctggtttctt
    46801 gcgcaatgcg acttcactcg ggcgtttttc cagattatgc tgaaaaatta cctcaggaag
    46861 aaaagatgga aaaagaagat tcatttcccc aacgcgtctg gcaaatcgtc gccgctattc
    46921 ccgaaggcta tgtcaccact tacggtgatg tggcgaaact ggcgggatcg ccccgcgccg
    46981 cgcgccaggt gggcggtgtg ttaaagcgtc tccctgaagg cagcacctta ccctggcacc
    47041 gggtggttaa tcgccacggc acaatttcgc taaccggacc ggatttacag cgtcagcgac
    47101 aggcattact ggcagaaggt gtgatggtat cgggaagcgg gcaaatcgac ttgcagcgtt
    47161 atcgctggaa ctactaaccc tctccgggcg gagagggtta acgtcgctta atattgcgta
    47221 ggagctggaa ctgccgaaga cggattcacc tgagttggtg aagtcgaagg tacggtagtc
    47281 gttgcgccac cgctggcctg aaccggcacg gcggtttgct gtaccggcac caatgtcagg
    47341 tcggctttag ttccgccctg gttgatcacc ggctgaacgg tatcggtgat aaataccagt
    47401 ttgtcattca cggtaatcgc cgcactcaac agaatacgcg cgttcggctg aacatctgcc
    47461 gggttaaatg gcagaacaaa gctgaatggt gactgtttac cttcagtacg caccgctttc
    47521 tgcgccagca cttttgacgg tgcatcggct aacgacgcgt cagaaagtgt cacggtcagc
    47581 acagcatcag gcggcagtgc gactttctga cggatccaga cggtaccgga gacattcggt
    47641 tgctggatag ctggttgttg tgttgctgaa atagacgtat ttgcagccgg tgctggcgtc
    47701 tgaatatccg cgcttttatc tgcgcaagcc gccaacgcaa tcgcaaccgc taaaccactg
    47761 gccatgtgca cgagtttcat tcatttctcc ttattatcaa tgcaccagcg ggctaacttt
    47821 cctcgccgga agagtggtta acaaaatagt aacgtcaaca agtgtggcac acatcacgca
    47881 tttctgcctg taattagccc gtaattcaga ccattgcacc catcggacca gtagcaaatt
    47941 tgcgttatac tcaactcact ttggcttgct gcggcagctt tgttactgga gagttatatg
    48001 agtcaggcgc taaaaaattt actgacattg ttaaatctgg aaaaaattga ggaaggactc
    48061 tttcgcggcc agagtgaaga tttaggttta cgccaggtgt ttggcggcca ggtcgtgggt
    48121 caggccttgt atgctgcaaa agagaccgtc cctgaagagc ggctggtaca ttcgtttcac
    48181 agctactttc ttcgccctgg cgatagtaag aagccgatta tttatgatgt cgaaacgctg
    48241 cgtgacggta acagcttcag cgcccgccgg gttgctgcta ttcaaaacgg caaaccgatt
    48301 ttttatatga ctgcctcttt ccaggcacca gaagcgggtt tcgaacatca aaaaacaatg
    48361 ccgtccgcgc cagcgcctga tggcctacct tcggaaacgc aaatcaccca atcgctggcg
    48421 cacctgctgc cgccagtgct gaaagataaa ttcatctgcg atcgtccgct ggaagtccgt
    48481 ccggtggagt ttcataaccc actgaaaggt cacgtcgcag aaccacatcg tcaggtgtgg
    48541 atccgcgcaa atggtagcgt gccggatgac ctgcgcgttc atcagtatct gctcggttac
    48601 gcttctgatc ttaacttcct gccggtagct ctacagccgc acggcatcgg ttttctcgaa
    48661 ccggggattc agattgccac cattgaccat tccatgtggt tccatcgccc gtttaatttg
    48721 aatgaatggc tgctgtatag cgtggagagc acctcggcgt ccagcgcacg tggctttgtg
    48781 cgcggtgagt tttataccca agacggcgta ctggttgcct cgaccgttca ggaaggggtg
    48841 atgcgtaatc acaattaaaa aaatagccgg aggtgaaaac cgtccggctg ttttttgcag
    48901 tgcttgttac gcgttatagg cattctcgcc gtggctgttg acatccagcc cttctcgctc
    48961 ctgctcttcc ggtacacgca gaccaaccgt cagatccgcc aatttgtagc cgataaatgc
    49021 cacaacaccg gaccagacga tcgtaatggc gatgctttcc agctgtacca gcaactgatg
    49081 gcccatcgtc acaccttcag cgaagcccac gccgcccagc gagctggcgg caaaaatccc
    49141 ggtcatgata cagccgacaa tgccacaaac gccgtgcaca ccgaagacat cgcagggatc
    49201 atccacccgc agcaagcgtt tgagcatggt aacgccccac aagcccgcca gaccagctac
    49261 cacgccgata atcaacgcgc cgccaacccc aatgtagccg caggctggcg tcacgccgac
    49321 cagaccggca atcgcgccag aacacgcccc cagcagtgaa ggcttaccac gcagcgccca
    49381 ttcaccgaag atccagccaa gaattgccgc cgccgttgcg accacagtat tcacaaatgc
    49441 cagtgccgcg atttcattcg ccgtgcccgc tgacccggcg ttaaagccaa accaaccgat
    49501 atagagaatg gcagtcccgg tgaagaccat cggcaggttg tgcggtttaa acgcctcttt
    49561 accgaagccc acgcgttttc ctatcagata cgcgcccacc agaccggcga ttgcggcgtt
    49621 aatgtgcacc acggtgccac ccgcgaaatc cagcgcaccg tgagaagcca gcaaaccacc
    49681 gccccacacc atatgcgcaa tcggaatgta agagagcgtc agccatacca ccacgaaaat
    49741 caacacagct gagaagcgga ttcgttccgc cagcgcccca actatcaagc cgacggtaat
    49801 gcaggcaaac gatccctgaa acgccacgtg gatatactga taaatgctgc ccatcaccgc
    49861 cgtcagttcg atgtttttca gcatcaacca gttaatgttg ccgaagaagt tgttgccctc
    49921 accaaacgcc agcgagtaac cgtaaaccac ccagagaata cagaccagtg caaatgtcac
    49981 cgtcacctgc gtcagcatcg acagcacgtt tttgccgcga atcaacccac cgtaaaacag
    50041 ggcaatcccc ggaatagtca taaacagcac cagcgcagta caaatcatca taaacgcatt
    50101 gtcggcttta tcggccaccg caggtgcagc cattaccagt cccggaagca tcgccagtga
    50161 agcaagccca gtttttatcg tcgctatctt catttttcgt tcctgttgct gtgtgccaga
    50221 gattacagcg ccgcttcgtc ggcttcgccg gtacgaatac gaatgacgcg ttgcaattca
    50281 gcgacgaaga ttttgccgtc gccaattttt ccggtgtaag ccgccttact gacgatatcg
    50341 atcacttcat cgagttggtc atcagcaatc gccacatcaa tttttacttt tggcaggaaa
    50401 ttgacgctgt attccgcccc ccggtacagc tcggcatgcc ctttctgacg cccgaaacct
    50461 ttcacttcgg tgacggtcag gccctgaata ccaatggaag ataacgcttc acgaacgtct
    50521 tccagcttga atggtttgat tatcacggtc accagcttca tagatcccct ccggtcagaa
    50581 ttcggtaatg gttctgctac acgaagaagg tattgcaagc ggtgtgccag aaatgaaaaa
    50641 cgagaaagag agcaggaagt taagaagttt gaaaatgaaa acgcactatg acagtgcaca
    50701 gtgcgttaca tttttgcacc aacgatgaaa tattgcgcta ttcaggcgct caatgattcc
    50761 tcttcacgca cgctggctgc cagctcttcg cccgcaagtt gcagttgata catctgccag
    50821 tagcgtccct gggccgccag cagttgctgg tgagtgccct gctccacggc ttgcccacga
    50881 tgaagcacca gaatggtgtc ggcatcaaca atggtcgata agcggtgagc aatcactacc
    50941 agcgtggtat gttcacgcac cgccgccaga gcatgttgaa tcgcctgttc agtaccggag
    51001 tcaatgctgg cggttgcctc atcaaggatc aggatttgcg gcgtctcgac cagcacgcgc
    51061 gccagtgcca gcagttgctt ttgcccaact gagagattat tcccctgctc gcccagcggc
    51121 gtgtaaatac cgtcgctcat gctacgcgcc agctccgcca gttgcacggt ttccagcgcc
    51181 tgccagacgc gttcttcgga gatatcccgc cccagcgtca cgttggcgag gaaggtatcc
    51241 gccagcacca ccggatcttg ctgcaccatt gccacgccct ggcgcagcgc gctgtgactt
    51301 agcgaactta atggacgacc atcaaggcga atctcacctt ccgttagcgg gtaatagccc
    51361 atcaataaac tggcgagggt gcttttgcca ctgccggtat gcccgaccag cgccacaaaa
    51421 ttgcgcgaag gcacagagag attaatgttc tttagcacca gattgtcatc gcgataagca
    51481 aatgacacgt tatcgacttc gatggtgcca ctctgtaacg ggcgatcatc attgccatat
    51541 tgctggcgcg gtccgtccat cagttcaaac acgcgctcac cagcaacaac agcctgttgc
    51601 agcatcgcct gttgcgtggt cagttcgatt aatggttcgt taagtcgccc aagatagctg
    51661 ataaacgcat acagcacgcc cacttcaatg gtgccgctgg cggagaagcc aaacagcatc
    51721 aacaagccac aaagaatgag cgatgaaaac agactcagca gcggacgcag cagaaaaccg
    51781 tcgaggcgca gggtttgcat cctcgccata tagtgtgaac gactggcctc ccccatacgt
    51841 tcgccaaatc gcgcctgctg acgaaactgc tggataacgc tcatgccatt gatgatttcg
    51901 ttaaagccgt cgttgatatc cgccagatag gcgcgcacac gacggacaat cggcgtgctg
    51961 taacgctggt atatcaccat taccaccagc accaccggga aaatcattat cgccaccagt
    52021 gccattcgcc agtcgaggct gaacatcgcc accagcatcg cgcccaccag cgcggcactg
    52081 cgcaggacag ttgccactac ggtaacgtag agatcgcgga tcacttcagt gtcattagtg
    52141 acgcgggaaa tcacctgccc gacgggttgg gtatcaaact cgcttaatgg ctggcgtaac
    52201 gcagcatcca tcacgtcggt acgcaactgt tgcactacgc ctactgccgc ccgattaaac
    52261 agcagcgact gcgcgtaatg tagcccggcg gcaaacagtt gcagcccaac atacgccgca
    52321 gccagccctg caaccacttt caacggcagg ttatttttcg ctaccatatt gtcgataaaa
    52381 tagctgataa gcagcggccc actgacttct gccgccgccg caacccacat catcaggacc
    52441 gcaatcccca gcggtttacg ccacggcgaa ccgtacgcta acaggcgctt gagagtcggc
    52501 cacagttggc taaaactacg catcgacggc ctcctcgcga ttttccggag cgtcgtcgag
    52561 cgccgcctcc agttgttgat agcgatacat atcgcgatac cagccgcttt gttgtgccag
    52621 cacatcatga ttgccacgct gggcgatatg tccgtgctgc atcacaataa tttcactggc
    52681 ttccgtcagt gcagaaaggc gatgggcact gatgattacc gttcttccct gcccccactg
    52741 acgcaggtta tgcaggatct ggtgctcagt gcgtccgtcc accgccgaaa gcgcatcatc
    52801 aaggatgagg atttccgcgt tgactaataa cgcacgagca atggagatac gctgtttttg
    52861 cccgccggaa agcatcacac cgcgctcgcc cacctctgta tcgtaacctt gcggtagacg
    52921 caaaatatcg tcatgtacgc tggctaaccg cgcgacatgc tcaatctctt gctgggtggc
    52981 attcgggcaa cccagcgcga tgttattcgc cacagtgtca gaaaaaagga atggcgtctg
    53041 gctaactacc gccaggcggc tacgccagct atcgagttgt aacttcgtca gaggaatatc
    53101 atgaaagcga atatccccct cgctgacgtc gaaatgacgc tgaatgagcg acaacagggt
    53161 acttttgccg gaaccagtcg gcccgcagat acccagcatc tgaccgggtt tcagggcgaa
    53221 attgacgttt tccagcgcag gatggtcagt ctgcggatac gtgaactggt gaatatttac
    53281 atccagttcg ccacgccctt ccggcacggg ttcgctacca tcgttcacca ccggcgcttc
    53341 cgccagcatc gcgcgaatac ggctgtacgc agcactacca cgttccacaa tgttaaacat
    53401 ccatgccagc gccagcattg gccaaatcat cagacctaaa tacatcataa aactggtgag
    53461 ctggcccagc gttaaactgc cctgcaccac catccaacta ccgccgccaa tcgccagcaa
    53521 gttcgccata ccaatcgcga tatagatggt cgggtcgaaa cgagcatcaa tacgcgccac
    53581 ccgcatgttt tttttgccgg tatcttcggc atccgcggca aataacgccg actggcgatc
    53641 ttccagacca aaggctttga tcatgcggat actggtgagg ctttcctggg tgcggtcatt
    53701 aagactggaa aacgccgcct gtgccagctt aaagcgttca tgcaaagcat cgccgttgcg
    53761 cttaatcatg atcgccatca ctggcatcgg caacagggaa aataaggtca actgccagct
    53821 aatttgcgta gacatcataa tcaacacagc gcagcccatc accagtgaat ccaccagcgt
    53881 cagcacccct tctccggcgg caaacacgac gcgatcgacg tcattggtcg cacgagccat
    53941 gaggtcaccg gtgcgatgac gcaggtaaaa ctcaggatgc tgccggctta gctgacggta
    54001 ataatcttca cgcagttcaa cagccagttg ataagacgca ccaaacagca atacccgcca
    54061 gacgtaacgc aggagataaa ccacaacggc aatcagcacc atggtggcga tccacatcag
    54121 gatctgcccg gtagtaaagt gttgttctgt cacgccatcg acaacaatac caaccacttt
    54181 tggcggaacc agttgcagca tcgcgataat gacaagcaag gcgacagccc cgagatagcg
    54241 acgccattcc cgacggaaat accagcttaa ttgagcaaat aatcgcacgc gttgtgtcct
    54301 gacctgattc tggatattta ttcgatgggt aaagaagtgg tgtatttaat ctgttccatc
    54361 gcgaagctgg aagtgacgtc cgacagcccc ggcacgctgt ttaccagacg cttataaaac
    54421 tcgtcgtagc gtttcatgtc ggcaacctgg acgcgcataa gataatcgta ttcaccagcc
    54481 atgcgccaga accccagcac ttctggcatt tcggtaacca ccgtgacaaa gcggcaatac
    54541 cattcgctgc tgtgatgttg cgtttttatc agcacaaaag cggtcaggcc gaggcctatt
    54601 ttttccggat ccagcagggc gactttgccg ataaggatac cgtcgtcctc cagccgtttc
    54661 aggcgcttcc agcaaggggt ggttgtcaga ttaacggctt cagccagtgc ctgcaaagag
    54721 agggtgcaat cctgctgcag taaggccagc agcttacggt caattttatc taacatagcc
    54781 cttccacaga gaattttttt ctcttttaat tttattttaa aggtgaaatc acgacaattt
    54841 attctgtgcg gtttaaacac cacggcacaa aatgacaaat tcaacgcaaa aaaaaccggg
    54901 caattgcccg gtgctggaag ggatctcgtt attcggggga ataaggtaga tgtggatagt
    54961 ccagccagtg cgtcaaatag tgagagacag cctgatttcg gcaatgtcca atcaccggta
    55021 aatgcgggag ctccgcgcgc agttgcggca tcgcattgcc cataataaat ccgctaccga
    55081 cgctgactaa catttcgcga tcgttcatcg catcaccaaa ggccatgcaa tcgcgcaacg
    55141 ataaacctaa atgttgggtc agcaccgtca atgcagcgcc tttattgcag cccaccggca
    55201 gcacttcgag gcaatccgtg gcggaaaaac acaaatgtgc acgctcgcct aatgcttcgt
    55261 atagctggat ctgcaagcgt gtaagatcgt cgtgatcgcc acagaagcag atcttggtga
    55321 cgctgccgag tggcattttt ttgacatcga ttatctgata acgaaaaccg ctatagacaa
    55381 atgcctgcaa caacgcaggg atctctttcc cggtaaacca accgtcgtca ttgaagatat
    55441 gcatgctggc tcgggtatcc cattgctgat acagcaccag ctccgcgaca tccgcaggta
    55501 aatcatcacg atgtaaaagt tcaccttcca gagaatgcac gcgcgttccg ttgccggtaa
    55561 tcaaatacgc atccagcgat agcgccccga gaatatgctg catctccagc gcatgacgcc
    55621 ccgtggcaaa agtgagggta atgtcgcgtt cacgcagtcg cgccaaagta gagagggttt
    55681 tctcacctaa atgatggtca ggcatcaata aagtgccatc catatcaaat gctgccagac
    55741 gagccatttc tttctccact ctgtgacacg gttaatggtg attgagtatc acctgatata
    55801 tacggaagta atagtgaata gttaaataat attgttccgg gtttatatgc gattgctcaa
    55861 ccgtcttaac cagtatcaac gtctgtggca accttccgcc ggaaagccgc aaaccgtcac
    55921 cgtcagcgaa ctggccgaac gctgtttttg cagcgaacgc catgttcgta cgctgttgcg
    55981 tcaggcacag gaggcgggat ggctggagtg gcaggcgcag tcaggacgcg gaaagcgcgg
    56041 acaattacgc tttctggtca cgccggaatc gctacgcaat gcgatgatgg aacaggcact
    56101 ggaaaccgga aagcagcaag atgtgctgga gctggcgcaa ctggccccag gtgagctgcg
    56161 cactctgtta cagccgttta tgggcggaca atggcaaaac gatacaccca cgttgcgtat
    56221 tccctactat cgcccgctcg aaccgctaca accaggcttt ttgcccggcc gtgccgagca
    56281 gcatctcgcc gggcagatat tttccggcct gacccgcttc gataataata ctcagcgccc
    56341 gattggcgat ttagcgcatc actgggaaac ctctactgac gggttacgct gggactttta
    56401 tcttcgttca accctacact ggcataacgg cgatgcagta aaagcctcac acttacacca
    56461 gcgattattg atgctgttac aactgccagc actggatcaa ttatttatta gcgtgaagcg
    56521 tattgaagtc acccatccgc agtgtctgac cttcttttta catcgccctg attactggct
    56581 tgcgcaccgg ctggcgagct attgcagcca tctggcgcat ccgcaattcc cactgatcgg
    56641 cacgggtcct tttcgcttaa cacaattcac agcagagctg gtgcgcctgg aaagccatga
    56701 ttattaccat ttacgtcatc cgctgcttaa agcggttgag tactggataa ctccgccgct
    56761 tttcgaaaaa gatttgggaa ccagttgtcg gcatcccgtg caaatcacca tcggcaaacc
    56821 ggaggagctg caacgggtca gccaggtcag tagcggcatc agtttaggtt tttgctattt
    56881 gacgttgcgc aaaagtcccc gactctccct ctggcaggcg cgaaaagtga tctccattat
    56941 tcatcaatcc ggtttattac aaacgttaga agtcggagaa aacctgatca ccgccagtca
    57001 tgcattactg ccaggctgga ctattccgca ttggcaggta ccggatgaag tcaaactacc
    57061 gaaaaccttg acgctggttt atcacctacc gatagaactt cataccatgg cagaacgcct
    57121 acaggcgaca ctggcagcgg aaggctgtga actcacaatt atttttcata acgcaaaaaa
    57181 ctgggacgac acgaccctac aggcacacgc agacctcatg atgggcgaca gattaattgg
    57241 cgaagcaccg gaatatactc tggagcaatg gctgcgctgc gatccgctgt ggccacatgt
    57301 tttcgacgct ccagcatacg cacatctaca atcgacactg gatgccgtgc aaataatgcc
    57361 tgatgaagaa aaccgattta atgccctgaa agcggttttt agccagttaa tgacagatgc
    57421 gacgctgacg ccgctgttca actatcacta tcgcattagt gcccctcccg gcgtgaacgg
    57481 tgtgcgactg acaccgcgcg gctggtttga atttaccgaa gcctggcttc ccgcgccatc
    57541 gcaatgaata gctggtccgg gttaatcgca ggcgttacca taacgctttt attgttcaag
    57601 caggattatc tatgaaacgt gctgtcgttg tgttcagtgg aggtcaggat tccaccacct
    57661 gtctggtgca ggcattacaa caatatgatg aagtccattg cgtgacgttc gattacggtc
    57721 agcggcatcg cgcagaaatc gacgtggcac gcgaactggc gctgaaactg ggggcacgcg
    57781 cgcataaggt gctggatgtc accctgctca acgagctggc ggtcagtagc ctgacgcgtg
    57841 acagcattcc ggtgcctgat tatgaacctg aagccgatgg tatcccgaat acgtttgtcc
    57901 cagggcgtaa tattttgttc ctgacgctgg cggcaatata tgcgtatcag gtaaaagcag
    57961 aagccgtaat tactggcgtc tgcgaaacgg atttctccgg ctacccggat tgccgcgatg
    58021 agtttgtgaa agcactaaac catgccgtca gtttgggcat ggcgaaagat attcgttttg
    58081 aaacgccgct gatgtggatt gataaagcgg aaacctgggc gctggcagat tattacggca
    58141 aactggattt agtccgtaac gaaacgttga cctgctataa cggctttaaa ggcgacggtt
    58201 gcggtcattg tgcggcatgt aatttacgcg ccaacggttt gaatcattat ctggccgata
    58261 aaccgacggt gatggcagcg atgaagcaga aaaccgggtt gaggtaatta ttccgggtgt
    58321 cgccggatgc ggcttgagca tccggcacca caaaacgttt acttaaccat ctgctccagc
    58381 ttttcgcgca attccccttc cagagctaat gctttctgcg ttttaagatc aatacaaaca
    58441 aacgtaataa gcgcatccgc taccacctgc ccttccggct ccagtgtaat gacctggctt
    58501 aagatgccgc ttttaccgtt taattgctgc aactgactgg taatagttaa caggtcactt
    58561 aataccgctg ggcgacgata gttaatattg atattgacca cgacgaaggc gatgttatgg
    58621 gccgtcatcc actgaaaact gtcgctattt tccaacccat cccagcgggc ttcttcgaga
    58681 aattcaaggt agcgggcgtt gttgacgtgc tggtaaacgt cgagatgata tccacgaact
    58741 ttgatttgtg tttgcatagc gcaataacct tacgttgttg ttataagtac agaggtcata
    58801 actggtatga cctcttcagt ctggcaaaaa attgccacta tgcaaattaa ttacagggtt
    58861 aataccgcca gattacgttc caccagcgaa ttgcccatcc ccggcacctg ctttagatcc
    58921 tccacagttt taaacggacc gtactcttcg cgataactga caatcgcctg cgctttcttc
    58981 aggccaacgc cattcatcgc gcgggctagc tcttccgcgc tggcattatt aatgctgacc
    59041 cgggtgcctt cttcgtcact ggctttcgcc ggtactgctg ctttactttg tgctgcagga
    59101 gcttccgctt tggtttctac cgccgtcggt ttcgccacag aagctgccgc cagcgcgcta
    59161 tgagacattc cggcacaggc cagggacagg gtaatgagca gtgctttaat tccgtgtttc
    59221 atactgtttt ctccttgttt gttaacagtg gaatcacctt aacggcagtg aaaacagtaa
    59281 acaaatggca atgttcagaa atggaaaagg ccgcgaaagc gaccttttct tgttacagct
    59341 gcaacgcatt tttttgcgag gcggcttcag gattattgct gttccagcgc atcgccaatt
    59401 ttgattttcg cctctttacg caggttactc atcagagctt caaagacgat ttgtgcgttg
    59461 ttctgggtga taccctgcac catcgctttt ttctgatctt ccggcattga accttgtttc
    59521 acttcatcca gcgccagcag aaccacatta ccttgcatat cggtcgccat accgtagctc
    59581 ggtttgtctt tcgctggcag tggcagtgca aacgccgcct ggctaatcgg gtcacgaccg
    59641 gaacggctta aggttttcgg ctcgccaaat ttcagaccgg cagcctgcat agcttccgca
    59701 cctttgccgg ctttcaaatc aaccagcagt ttctcagcat ccactttcgc ctgttgttca
    59761 gctttgttgt gctgaaccaa tgccttaact tgttcctgaa catctgccaa cggtttcacc
    59821 gcttccggtt tgtgctcgct gatgcgcagc acgaatgcgc ggtcgccgtc tacggtgatg
    59881 atgtcagagt tgatgcccgg cgcgccgttt tcacctacca gaccgccgtt aaagatagcg
    59941 tcggcaaccg gcttgaagtt caactcttcc ggcaggttat ctttgctgaa ccaacccgtc
    60001 tgagtggctt taacgccggc agcttgctct gcaccggcca gagactcggt gtcgttgctt
    60061 gccgcatcgc tcactttctg ctgcagcgcg tagtacgcat cgagggcttt ttcgtgtttc
    60121 actttcgccg caatgtcgtc acgtacttcg tctaacgatt tcactttcgc tggctgaatg
    60181 tcgtccagac gtacaatcag gaaaccgacc gaagatttga tgacaccaga cagttggcct
    60241 ttttctttca gaccagcatt tttcagttcg tccgggatag tggcatcttc taaccaaccc
    60301 atatcgccgc cgttacgagc agagataata tcggcagatt tttctttggc taatgcagca
    60361 aaatcaccgc ctttattcag ctcatcaagt accgctttcg cttcatcttc agttttggtc
    60421 tggatgatgc tgtagcgggt acgctgcggc tgggtgaatt gatcctgatg ctggtcgtag
    60481 tagctctgga tatccgcatc gctaaccggt tgctgcatcg ttgcggcatc cagcttgatg
    60541 taactcacgc ggaattgttc cggcgtcatg aaattgtttt tgttttgttc gtagtagctg
    60601 gcaatctcct gttcggtcac aggctgcttc gccgccagcg cgttaacatc gatagtcgcc
    60661 tcacgcacca cgcgttgttg cgcgaccagt gccgccagct cgtcggtttc acctttcagc
    60721 ataaaatcgg taccggcaac gccgttaatc agctgttggg tagtgagctg gttacgcagc
    60781 gcctgggcgt actgatcggc ggtcatcccc atctggttga ggataccgtt atagcggctg
    60841 ttatcaaatt tgccgtcaac ctggaaggct ggggtcgcga aaatcgcctg tttaacctgc
    60901 tcatcgctga tacccagttt cagctcacgt gcgtactgat ccagcagcgc ctcgtcgatc
    60961 agacgattca gcacctgttg acgcagggtt ttcatatagc cttcgttcgc tgccagctcg
    61021 gagtattgat cgcccagctg ttgctgcatg cgattacgct cgctgttgaa ggcgttctcg
    61081 aattgcccac ggctgatttc ctggtcattc acttttgcgg cgtagttatt gcctccgcca
    61141 atcaggtaac cactcacgcc ggtcaatatg aacgacacga taatgatacc gaaaataatc
    61201 ttgagcacga gactgtttgc agccgtgcgt aagctgtcca tcatggtgta acaacactcc
    61261 gctgtagatg actgtgtacc tcacgcaacg tatcgatgcg cgcaaaggcc tattgtgaca
    61321 agaaacgggg gcaattgtca gcccacaaga cgcagaaagt caccgaatac aaataaaaaa
    61381 ggcacatcag tagatgcgcc cttgaacttc gtcacatccc cactggggac aacgcttagt
    61441 ttaccgcgtc tttcagtgct ttacctgcac ggaagctcgg tactttagca gcagcgatgg
    61501 tgatctcttt accggtctgc gggttgcggc cagtacgggc agcacgctct ttaacggcaa
    61561 aagtaccaaa acctaccagt gctacatcat ccccttcttt cagagattca gttacggaag
    61621 caataatagc atctaacgca cggccagccg cagctttaga gatatcagcc cctgcagcaa
    61681 tcttgtcgat caattgagat ttattcactc ttctcttcct ctttataatt tatatcgcac
    61741 ttgaatcctt caaggtacga acgcgcagca gttatatcag gccagccatc cccttacaac
    61801 accccttaat aagggcaagc ccgatccgcc atctaactta gcgagacaaa aaaaggctgg
    61861 caagcccgaa ttagcctgcc agccctgttt ttattagtgc attttgcgcg aggtcactat
    61921 tttgcagtca caacctgcat accagacggt tcattttgca gcgccagagt cagaacttcc
    61981 tcaatgcgct tcacaggatg aatgtccaga tcggcaatta cgttgtcagg aatctcttcc
    62041 agatcgcgtt tattttcgaa cggaattagc actgttttaa tcccgccgcg atgcgctgcc
    62101 aggagttttt ctttcaaacc accgatcggc agtacctgac cacgcagagt gatctcaccg
    62161 gtcattgcca catcggcacg aaccgggtta ccggtcaggc aagaaaccag cgcggtgcac
    62221 atagcaatac cggcactcgg accatctttc ggcgtcgcac cttccggtac gtggacgtgg
    62281 atgtcacgtt tttcgtaaaa atcagggttg atccccagtt tttccgcacg cgcacgaacc
    62341 accgttaacg ccgcctgaat ggactcctgc atcacttcgc cgagcgaacc ggtataggtc
    62401 agtttgcctt tacccggaac acatgcggtt tcaatggtca gcaagtcacc gcccacttcc
    62461 gtccacgcca gaccggttac ctgaccgaca cggttttcgt tatccgcgcg accatagtcg
    62521 aaacgctgaa caccgagata gtcatgcagg ttatcgccgt taatttcgat atgttttaat
    62581 gacttatcga gcagtaactg cttaaccgct ttgcgacaca gtttggagat ttcacgctcc
    62641 agaccacgca cgcccgcctc acgggtgtag taacgaataa tgccgataat ggcgctatcg
    62701 tcgacggtca gctcaccttt tttcagtgca ttacgttcaa tctgcttcgg cagcaggtga
    62761 cgtttggcga tgttcagttt ttcatcttcg gtataaccgg agaggcgaat cacttccata
    62821 cgatccagca gcggtgccgg aatgttcatg gagttcgacg tcgcgacaaa catcacgtcg
    62881 ctgagatcgt aatccacttc caggtagtgg tcgctgaacg ctacgttctg ctctggatcc
    62941 agcacttcaa gcagtgcaga ggccggatcg ccacgcatgt cagaagacat tttgtcgatc
    63001 tcatcgagca ggaacagcgg gtttttcacg cccactttcg ccattttctg gatcagttta
    63061 cccggcatag aaccgatgta agtacggcgg tgaccacgga tttccgcttc atcacgcacg
    63121 ccgcccagcg ccatacggac atatttacgc ccggtggctt tggcaatgga ctgaccaaga
    63181 gaggttttac ctacccccgg cggccctacc aggcagagga tcggtccctt gattttgttg
    63241 acacggcttt gaaccgcaag atactcaagg attcgatctt tcacgcgctc cagaccataa
    63301 tggtcggtat caaggatttc ctgcgcctga cgcaggtctt ttttgacctt gctacgcgca
    63361 ttccacggca cctgtaccat ccagtcgata taaccacgca ctacggtcgc ttctgccgac
    63421 atcggagaca tcattttcag cttctgcaac tctgcttccg ctttctcttt tgcctctttc
    63481 ggcatcttcg ccgcgtcgat tttgcgcttc agggcttcgt tttcgtccgg cgcgtcgtcc
    63541 atttcaccga gttctttctg aatagctttc atttgctcgt tcagatagta ctcacgctgg
    63601 gatttctcca tctgcttttt aacgcggttg cgaatgcgtt tctcaacctg cagcagatcg
    63661 atttccgatt ccatcattgc catcagatat tccagacgtt cgttaacgtc ggacatctcc
    63721 agaacagact gtttgtcagc cagtttcagc ggcatatgtg cagcaatggt atccgccaga
    63781 cgcgccggat cgtcgatgct attcagcgac gtcagcactt ctggtgggat ttttttgttc
    63841 agcttgatgt agccttcgaa ctggctgatt gcagtacgca ccagcacttc ctgttcccgc
    63901 tcatcaatgg tcggcgactc cagatactcc gccttcgcag aaaagtgttc gccattgtca
    63961 gagagcgcag aaatacgcgc gcgctgtaac ccctcgacca gcactttgac ggtgccgtca
    64021 ggcagtttca gcatctgcaa tatagaggcc acggtcccga cggtgaaaag atcgtttaca
    64081 cccggctcat ccgttgaagc ttctttctgc gcgaccagca taattttttt atcatggtcc
    64141 atcgccgctt ccagacaacg gatagatttt tcccgcccga caaataaggg gatgaccatg
    64201 tgcggataaa ccaccacatc gcgcagcggc aatacgggga tttcaatgcg ttcagaacgc
    64261 tcaggattca tagagctctc tcttagttta atttccgcca ggtaatcaga tgacacgact
    64321 gtgcttcacg ccatctatta acatgtacgt cagtatatgg ggatgtttcc cccacattca
    64381 acgccgagaa tagaggaaaa attaaagggg agataaaatc cccccttttt ggttaactaa
    64441 ttgtatggga atggttaatt attcaccaga tgcctgttgc gcttccggct tgccataaat
    64501 cagcaacggt ttgctttgac catcaattac cgactcgtcg ataaccactt tttcgacgtc
    64561 ttccatggac ggcagatcgt acatggtatc gagcagtgcg gcttctacga tggaacgcag
    64621 gccacgggca ccggttttac gcgccatcgc tttcttagcg atagcatcca gcgcctcgtc
    64681 acggaattcc agatccacgc cttccagatt aaacagcgcc tgatactgct tggtcagggc
    64741 gtttttcggc tctttgagga tctgaatcag agcttcttcg ctcagttcat tcaacgttgc
    64801 gacaaccggc agacgaccaa taaactcagg gataagacca aacttgatca gatcttccgg
    64861 ttcaacctgc gccagcagct cgccttcgct tgctttgtcg gacttcgctt ttaccgtcgc
    64921 gccaaaacca atgccggagc cggtttctac acggtgggaa atcactttat ccagaccggc
    64981 aaacgcaccg ccacaaataa acaggatctt agaggtatca acctgcaaga attcctgctg
    65041 cggatgttta cgcccacctt gcggtggaac agcagctacc gtaccttcga tcagtttcaa
    65101 cagtgcctgc tgtacgcctt caccggaaac gtctcgggta atggacgggt tgtctgactt
    65161 acgagaaatc ttgtcgattt catcgatgta gacaatacca cgctgtgctt tctggacatc
    65221 gtagtcgcat ttctgcaaca gcttctgaat gatgttttca acgtcttcac ccacataacc
    65281 ggcttcggtc agtgtagtcg cgtcggccat ggtgaacgga acatccagca ggcgcgccag
    65341 cgtttcagcc agcagcgttt taccggaacc ggtcggaccg atcagcagaa tgttactttt
    65401 gcccaactcg acgccattgc tggtatcgcc gttgcgcaga cgtttgtaat ggttgtatac
    65461 cgcgaccgcc agcacttttt tcgcctgttc ctggccgata acgtaatcgt ccaggtggtt
    65521 gcgaatttca tgcggcgtcg gtagcgcact gcgttcacga tgcggtgcaa cttctttaat
    65581 ctcttcgcga atgatgtcgt tacataaatc aacacattcg tcgcagatat acacggatgg
    65641 accggcaatc agcttgcgca cttcatgctg gcttttgccg caaaaagagc aatacagcaa
    65701 tttgcctgag ccatctttgc gtttatctgt catgggtcaa aacctcttct ttgttctttg
    65761 tgccgcacac gacgacgcaa atgccattct caggcgcaag ccgcttacag cgttgtgccg
    65821 ccctggataa gtatagcggc acagttgcgc ctctggcatc aattacgatg ggtcagaatc
    65881 gaatcgacca gaccgtattc caccgcttca ggggcggaaa ggaagcgatc gcgctcggta
    65941 tcacgttcaa tctgttctaa tgattgaccc gtatgaagcg ccataagttc attcatgcgc
    66001 cctttaactt tcagaatttc acgggcatga atttcgatat cggtcgcctg gccctggtag
    66061 ccgcccaacg gttggtgaat catcacgcgc gaattcggca ggcaaaaacg tttacctttt
    66121 gcccctgcgg tcagcaagaa agcgcccatc gaggccgcct ggcccataca gatggtgctg
    66181 acatcaggct tgataaactg catggtgtca tagatagaca tcccggcagt gatcaccccg
    66241 cctggggagt taatgtacag atagatatct ttttctgggt tttccgcttc caggaacagc
    66301 atctgcgcca caatcaggtt agccatgtgg tcttcaacct ggccagtcag aaaaatgacg
    66361 cgttccttaa gtagacgaga atagatatca aaagagcgct caccgcgtga ggtctgttca
    66421 atgaccatcg gcaccagcgc catatggggt gcaaagttat ctcgttcgcc gctgtatgac
    66481 atttccgtct cctggataaa attgaaaaaa cctgctgtac cgattgtaac cttatggacg
    66541 gattatcagc tagtccctgt gttatgggta cggcatcacc atatttcaag cataacaatc
    66601 ttttgttgtt acgctaacac cgaaagaggc ttttcgcacg gttccatgca aaattcatga
    66661 caaaaaaaag cccaccacct ggcggtgacg ggcctttgtg cgaatttagc gcgttatgct
    66721 gcgtaaatta cgcctgctgg ttcatcagct cgttgaaagt ggtttctttt tcagtcactt
    66781 tcgctttcgc cagtacagct tcaacagcct gttcttccag agcaacattg cgcatgttgt
    66841 ccatcagttc tttgtttttg ctgtagaact cgataacttc tttcggatct tcgtacgcag
    66901 aagccatctc ttcgatcagg cctttcacgc gctcttcgtc agctttcagc tcgttggtgc
    66961 ggataacttc gcccagcagc aggccaacaa ctacgcggcg tttagcctgt tcttcgaaca
    67021 gttcgcgcgg cagttccaga gcttgttttt cgttgccacc gaaacgctgt gcagcctggc
    67081 gacgcagaac gtcgatttcg ctgtcgatca gcgcagccgg tacgtcgatg tcgttagctt
    67141 ttaccagacc ttcgatcgcc tgagacttaa cgcggttacg gatggcgctc ttcagctcgc
    67201 gctccatgtt tttacgcact tcagcgcgca gaccttctac ggaaccatct tcaacgccga
    67261 aacgtttgat gaattctgca gtcagttccg gcagttcacg ctcttcaact ttcttcaggt
    67321 tgatagcgaa tttcgctgct ttacctttca ggttttctgc gtggtattct tccgggaagg
    67381 tcacgtcgat ggtgaactct tcgccagctt tgtggccttt gataccgtct tcaaagcccg
    67441 ggatcatacg accctggccc atcgccagta cgaaatcaga cgctttaccg ccttcgaact
    67501 cttcgccgtc tacagaaccg gtgaagtcga tggttacgcg gtcttctgct tcaacagcgc
    67561 cgtctttttc tttccaggtc gcctgctgtt tacgcagagt atccagcatg ccgtcaacgt
    67621 cagcgtcggt cacttcaacg atcggttttt caacttcgat cgcttccaga ccctgcagtt
    67681 caacttccgg ataaacttca aactctacag agtaagtgaa gtcttcaccc agcttgtatt
    67741 cgcccggaac ataagtcggt gcgccagccg gattgatttt ttctttaatg atggcgtcaa
    67801 tgaagttacg gctcatcagg tcacccagaa cgtcctggcg tacagacgcg ccataacgct
    67861 gagcaacgat attcattggc actttgcctt tgcggaagcc gtcaatacgt acttttttcg
    67921 caacgttgac cagctcgctt ttaacagcgg tctcgatgct gtcagcagcg atagtaatcg
    67981 ttacacggcg gccaaggcct tgagtggttt caactgaaac ttgcatcttg ttacctcaaa
    68041 aaatcacagt gctcggtcaa ctcttacccc gcaagcacag gttgttggct tcgcggaacc
    68101 gggatgttct tataatcaat cacattccct gttaccagaa tcatcccgaa agcattcaaa
    68161 taggacgcgg cattatagcg gcatcacttt tatgagtcga gaacggttat tgcgcgctgt
    68221 cgcgtatttt ttcacaattc ccgggcaatt ttcgtctgaa tgctgggcaa aaagcgcaaa
    68281 atccagacaa aacaaaacgg cccgcaggcc gtttttcata aaatctttag caacatactg
    68341 gaaaagcgcc gacagttgca aatgcgtttt tacgcgatgc ttcctgctcc acgacaggga
    68401 ggagaggcaa agacggtgtc ctgcaaccct tcccactcct taatagtgta agtatgcaga
    68461 gccagcgcat gaacggtagt agagagttcc tccgctaaag tactgtaaat cattcgatga
    68521 cgattcagaa aacgttcacc cgtaaaacga tcgctgacca gcacaacttt aaaatggctt
    68581 tcagagccgg ctgggacatt gtgacgatag ctttcatcca ctacttcgag gaatacgggt
    68641 tggaacgccg cccttaattt ttcttctatc cgctcacgta tcatcatgaa atatctcctc
    68701 cgacaacgct gagatgtcat ccatcccttt aaatactagc cgcttttacc gtttccattg
    68761 cagcttaaca acaaatattt aggtttcgtc ctggtttttc cgtcaagcgt atgaagttta
    68821 ctgatttaaa gattgaaaca caggcctcgc atcagtgttt cttttaccag gggcgattat
    68881 ttcgtcaaca tgatgaattt acatgcctta cccacttccc ctcgccgttg gcaatgttat
    68941 gatggcggga atttttacca aacacgctta agagtctctg agagcccgaa catgttcaaa
    69001 aaaatcctct tcccgttagt tgctctgttt atgcttgcag gatgcgcaaa accgccaaca
    69061 actattgaag tttccccgac gattacactg ccacagcagg atccaagcct gatgggcgtc
    69121 accgtaagca ttaatggtgc cgatcagcgt accgatcagg cgctggcaaa agtcacccgc
    69181 gataatcaaa tcgttaccct gaccgcctcc cgcgatctgc gtttcctgct gcaagaagtg
    69241 ctggaaaaac agatgaccgc gcgtggttac atggttggtc cgaatggccc ggttaatctg
    69301 caaatcatcg ttagccaact gtatgctgac gtgtcccagg gcaacgtgcg ctacaacatc
    69361 gcgaccaaag cggatatcgc catcatcgct accgcgcaga atggcaacaa aatgaccaaa
    69421 aactatcgtg ccagctacaa cgttgaaggt gcgttccagg cctccaacaa aaatatcgcc
    69481 gatgcggtta acagtgtgct gaccgatacc atcgctgata tgtctcagga caccagcatc
    69541 cacgaattca tcaagcagaa cgcgcgttaa tttctgccct ctggcccggt gcaagccggg
    69601 cctgtagacg cccatgtcca gtcaatattt acgtattttt caacagccgc gttcagccat
    69661 attgctgatc ctgggttttg cttccgggct accgctcgcc ctgacatccg gtaccttaca
    69721 ggcctggatg acggtcgaga atatcgatct caaaaccatt ggtttcttct ctctggtagg
    69781 ccaggcttac gtttttaaat tcctctggtc accgctgatg gaccgctaca cgcctccatt
    69841 ttttgggcgg cggcgcggtt ggctgctcgc cacgcaaatc ctgttattag tcgccattgc
    69901 ggcgatgggt tttctcgaac caggcaccca actccgctgg atggcggcgc tggcagtggt
    69961 gatcgctttt tgctctgctt cccaggatat agtcttcgat gcgtggaaaa ccgatgtgct
    70021 tccggcagaa gaacgtggtg cgggcgcggc aatcagcgtg ctgggttacc gtttagggat
    70081 gctggtttcc ggcggcctag ccctgtggct ggcagataaa tggctgggct ggcagggcat
    70141 gtactggtta atggcggcac tgttgatccc ctgtattatc gcgacgttgc ttgcaccaga
    70201 accaaccgac accattcctg tgcccaaaac gctggaacaa gcggttgttg cacctctgcg
    70261 agatttcttt ggtcgcaata atgcctggct tattttgctt cttatcgtgc tgtataagct
    70321 gggcgacgca ttcgccatga gcctgacaac cacgtttttg attcgcggcg tcgggtttga
    70381 tgcgggtgaa gtaggcgtgg ttaacaaaac gcttggctta ctagcgacca ttgttggcgc
    70441 attgtacggt gggattttga tgcagcgcct gtcactgttc cgggcactgc tgattttcgg
    70501 cattttacaa ggtgcgtcta acgccggtta ctggctgctg tcgattactg ataagcatct
    70561 ctacagcatg ggcgcagccg tctttttcga aaacctctgt ggcgggatgg gcacatcagc
    70621 ctttgtcgcg ctgttaatga cgctatgtaa taagtcattt tccgctactc aatttgccct
    70681 gctctcagcg ctttctgctg tagggcgagt ttatgtcggc cccgtggcgg gttggtttgt
    70741 tgaagcacac ggctggtcga cattctatct attctccgtc gccgctgccg taccagggct
    70801 tattttgctg ctggtttgcc gccagacgct tgaatataca cgagtaaatg acaactttat
    70861 ctcccgtacc gcatatccgg caggttatgc ctttgccatg tggacactgg cggcgggcgt
    70921 cagcctgttg gccgtgtggt tactgctatt gacgatggac gcgctggatt tgacgcactt
    70981 ctctttcctg cctgctctgc tggaagtcgg ggttttagtc gccctttctg gcgtcgtgct
    71041 tggtggtttg ctggattatc tggcgctacg aaaaacgcat ctgacgtaat ctgtaaatat
    71101 tatttagctg tagtaatcac tcgccgtaat tattacggct aaataaacat cagtatcgct
    71161 tattaatatt tgttcttttg tgcggcttag cgtttggaaa ttattggcgc catttataaa
    71221 ttctattttt cttacacgat tcagctaatg agtctttatt ttctcatcac ccagttgtca
    71281 ctctaatgat aattatttgt taaataattg ttttatttca cattggttat accaattgcc
    71341 cgcccagact ccttcagcac tccccttttg ttataacgcc cttttgcaac agcttcttaa
    71401 aatcaacctg atatgttttg caacatatgt gacctggcag ccaaatccaa gtaacaggaa
    71461 tttaatcatg tttacagtaa tgtaaccttc ccgtaaaatg cccacacact ttaaacgcca
    71521 ccagatcccg tggaattgag gtcgttaaat gagactcagg aaatacaata aaagtttggg
    71581 atggttgtca ttatttgcag gcactgtatt gctcagtggc tgtaattctg cgctgttaga
    71641 tcccaaagga cagattggtc tggagcaacg ttcactgata ctgacggcat ttggcctgat
    71701 gttgattgtc gttattcccg caatcttgat ggctgttggt ttcgcctgga agtaccgtgc
    71761 gagcaataaa gatgctaagt acagcccgaa ctggtcacac tccaataaag tggaagctgt
    71821 ggtctggacg gtacctatct taatcatcat cttccttgca gtactgacct ggaaaaccac
    71881 tcacgctctt gagcctagca agccgctggc acacgacgag aagcccatta ccatcgaagt
    71941 ggtttccatg gactggaaat ggttcttcat ctacccggaa cagggcattg ctaccgtgaa
    72001 tgaaatcgct ttcccggcga acactccggt gtacttcaaa gtgacctcca actccgtgat
    72061 gaactccttc ttcattccgc gtctgggtag ccagatttat gccatggccg gtatgcagac
    72121 tcgcctgcat ctgatcgcca acgaacccgg cacttatgac ggtatctccg ccagctacag
    72181 cggcccgggc ttctcaggca tgaagttcaa agctattgca acaccggatc gcgccgcatt
    72241 cgaccagtgg gtcgcaaaag cgaagcagtc gccgaacacc atgtctgaca tggctgcgtt
    72301 cgaaaaactg gccgcgccta gcgaatacaa ccaggtggaa tatttctcca acgtgaaacc
    72361 agacttgttt gccgatgtaa ttaacaagtt tatggctcac ggtaagagca tggacatgac
    72421 ccagccagaa ggtgagcaca gcgcacacga aggtatggaa ggcatggaca tgagccacgc
    72481 ggaatccgcc cattaaaggg gttgaggaag aataaagatg ttcggaaaat tatcacttga
    72541 tgcagtcccg ttccatgaac ctatcgtcat ggttacgatc gctggcatta ttttgggagg
    72601 tctggcgctc gttggcctga tcacttactt cggtaagtgg acctacctgt ggaaagagtg
    72661 gctgacctcc gtcgaccata aacgcctcgg tatcatgtat atcatcgtgg cgattgtgat
    72721 gttgctgcgt ggttttgctg acgccattat gatgcgtagc cagcaggctc ttgcctcggc
    72781 gggcgaagcg ggcttcctgc cacctcacca ctacgatcag atctttaccg cgcacggcgt
    72841 gattatgatc ttcttcgtgg cgatgccttt cgttatcggt ctgatgaacc tggtggttcc
    72901 gctgcagatc ggcgcgcgtg acgttgcgtt cccgttcctc aacaacttaa gcttctggtt
    72961 taccgttgtt ggtgtgattc tggttaacgt ttctctcggc gtgggcgaat ttgcgcagac
    73021 cggctggctg gcctatccac cgctatcggg aatagagtac agtccgggag tcggtgtcga
    73081 ttactggata tggagtctcc agctatccgg tataggtacg acgcttaccg gtatcaactt
    73141 cttcgttacc attctgaaga tgcgcgcacc gggcatgacc atgttcaaga tgccagtatt
    73201 tacctgggca tcactgtgcg cgaacgtact gattattgct tccttcccaa ttctgacggt
    73261 taccgtcgcg ttgttgaccc tggatcgcta tctgggcacc catttcttta ccaacgatat
    73321 gggtggcaac atgatgatgt acatcaacct gatttgggcc tggggccacc cggaagttta
    73381 catcctgatc ctgcctgttt tcggtgtgtt ctccgaaatt gcggcaacct tctcgcgtaa
    73441 acgtctgttt ggttatacct cgctggtatg ggcaaccgtc tgtatcaccg tgctgtcgtt
    73501 catcgtttgg ctgcaccact tctttacgat gggtgcgggc gcgaacgtaa acgccttctt
    73561 tggtatcacc acaatgatta tcgccatccc gaccggggtg aagatcttca actggctgtt
    73621 caccatgtat cagggccgca tcgtgttcca ttctgcgatg ctgtggacca tcggttttat
    73681 cgtcaccttc tcggtgggcg ggatgactgg cgtgctgctg gccgtaccgg gcgcggactt
    73741 cgttctgcat aacagcctgt tcctgattgc gcacttccat aacgtgatca tcggcggcgt
    73801 ggtcttcggc tgcttcgcag ggatgaccta ctggtggcct aaagcgttcg gtttcaaact
    73861 gaacgaaacc tggggtaaac gcgcgttctg gttctggatc atcggcttct tcgttgcctt
    73921 tatgccactg tatgcgctgg gcttcatggg catgacccgt cgtttgagcc agcagattga
    73981 cccgcagttc cacaccatgc tgatgattgc agccagcggt gcagtactga ttgcgctggg
    74041 tattctctgc ctcgttattc agatgtacgt ttctattcgc gaccgcgacc agaaccgtga
    74101 cctgactggc gacccgtggg gtggccgtac gctggagtgg gcaacctctt ccccgcctcc
    74161 gttctataac tttgccgtag tgccgcacgt tcacgaacgt gatgcattct gggaaatgaa
    74221 agagaaaggc gaagcgtata aaaagcctga ccactatgaa gaaattcata tgccgaaaaa
    74281 cagcggtgca ggtatcgtca ttgcagcttt ctccaccatc ttcggtttcg ccatgatctg
    74341 gcatatctgg tggctggcga ttgttggctt cgcaggcatg atcatcacct ggatcgtgaa
    74401 aagcttcgac gaggacgtgg attactacgt gccggtggca gaaatcgaaa aactggaaaa
    74461 ccagcatttc gatgagatta ctaaggcagg gctgaaaaat ggcaactgat actttgacgc
    74521 acgcgactgc ccacgcgcac gaacacgggc accacgatgc aggcggaacc aaaatcttcg
    74581 gattttggat ctacctgatg agcgactgca ttctgttctc tatcttgttt gctacctatg
    74641 ccgttctggt gaacggcacc gcaggcggcc cgacaggtaa ggacattttc gaactgccgt
    74701 tcgttctggt tgaaactttc ttgctgttgt tcagctccat cacctacggc atggcggcta
    74761 tcgccatgta caaaaacaac aaaagccagg ttatctcctg gctggcgttg acctggttgt
    74821 ttggtgccgg atttatcggg atggaaatct atgaattcca tcacctgatt gttaacggca
    74881 tgggtccgga tcgcagcggc ttcctgtcag cgttctttgc gctggtcggc acgcacggtc
    74941 tgcacgtcac ttctggtctt atctggatgg cggtgctgat ggtgcaaatc gcccgtcgcg
    75001 gcctgaccag cactaaccgt acccgcatca tgtgcctgag cctgttctgg cacttcctgg
    75061 atgtggtttg gatctgtgtg ttcactgttg tttatctgat gggggcgatg taatgagtca
    75121 ttctaccgat cacagcggcg cgtcccatgg cagcgtaaaa acctacatga caggctttat
    75181 cctgtcgatc attctgacgg tgattccgtt ctggatggtg atgacaggag ctgcctctcc
    75241 ggccgtaatt ctgggaacaa tcctggcaat ggcagtggta caggttctgg tgcatctggt
    75301 gtgcttcctg cacatgaata ccaaatcaga tgaaggctgg aacatgacgg cgtttgtctt
    75361 caccgtgcta atcatcgcta tcctggttgt aggctccatc tggattatgt ggaacctcaa
    75421 ctacaacatg atgatgcact aagagcggcg gttatgatgt ttaagcaata cctgcaagta
    75481 acgaaaccag gcatcatctt tggcaacctg atctcggtga ttgggggatt cctgctggcc
    75541 tcaaagggca gcattgatta tcccctgttt atctacacgc tggttggggt gtcactggtt
    75601 gtggcgtcgg gttgtgtgtt taacaactac atcgacaggg atatcgacag aaagatggaa
    75661 aggacgaaga atcgggtgct ggtgaaaggc ctgatctctc ctgctgtctc gctggtgtac
    75721 gccacgttgc tgggtattgc tggctttatg ctgctgtggt ttggcgcgaa tccgctggcc
    75781 tgctggctgg gggtgatggg ctttgtggtt tatgtcggcg tttatagcct gtacatgaaa
    75841 cgccactctg tctacggcac gttgattggt tcgctctccg gcgctgcgcc gccggtgatc
    75901 ggctactgtg cggtaaccgg tgagttcgat agcggcgcag cgatcctgct ggctatcttc
    75961 agcctgtggc agatgcctca ctcctatgcc atcgccattt tccgctttaa ggattaccag
    76021 gcggcaaaca ttccggtatt gccagtggta aaaggcattt cggtggcgaa gaatcacatc
    76081 acgctgtata tcatcgcctt tgccgttgcc acgctgatgc tctctcttgg cggttacgct
    76141 gggtataaat atctggtggt cgccgcggcg gttagcgtct ggtggttagg tatggctctg
    76201 cgcggttata aagttgctga tgacagaatc tgggcgcgca agctgttcgg cttctctatc
    76261 atcgccatca ctgccctctc ggtgatgatg tccgttgatt ttatggtacc ggactcgcat
    76321 acgctgctgg ctgctgtgtg gtaacaaaac ctctctatta aaaaggtgct acggcacctt
    76381 ttttcttagc attagaaaca tatccctctc gaaatattta ctaaaaaatc cgcatgttta
    76441 ccccattcgt ttgccgcttt acactagtcg cgaatttaaa acagaggtgg taatgaacga
    76501 ttataaaatg acgccaggtg agaggcgcgc gacctggggt ttagggaccg tattctcgtt
    76561 gcgcatgctg ggcatgttta tggttctgcc ggttctgacc acgtacggca tggctctgca
    76621 aggtgccagc gaagcattaa tcggtattgc cattggtatt tatggtctga ctcaggccgt
    76681 ttttcagatt ccgtttggcc tgctttccga ccgcattggt cgcaaaccat taattgtcgg
    76741 tgggctggcg gtgtttgccg ccggtagcgt tatcgctgcg ctttccgact ccatctgggg
    76801 aattattctg ggccgggcgc tacaaggctc tggagcaatt gccgccgccg ttatggcgct
    76861 gctttccgat ctcacgcgcg aacaaaaccg caccaaagcg atggcgttta tcggcgtgag
    76921 ctttggcatt acctttgcca ttgcgatggt gcttggcccg atcatcactc acaaacttgg
    76981 gctgcacgcg ctgttctgga tgatcgctat tctggcaacg accggcattg cgttgaccat
    77041 ttgggttgtg cccaacagta gcactcacgt acttaatcgt gagtccggaa tggtgaaagg
    77101 cagtttcagt aaagtgctgg cggaaccgcg gctgctgaaa ctcaactttg gcattatgtg
    77161 tctgcatatt ttgctgatgt cgacgtttgt tgccctgccc ggacaactgg ctgatgcagg
    77221 gttcccggcg gctgaacact ggaaggtcta tctggcgaca atgctaatcg cctttggctc
    77281 ggtcgtgcct ttcattatct acgctgaagt taagcgcaaa atgaagcaag tctttgtctt
    77341 ctgcgtcggg ttgatcgtgg ttgcggaaat tgtgttgtgg aacgcgcaaa cgcagttctg
    77401 gcaactggtg gtcggcgtgc agcttttctt tgtggcgttt aatttgatgg aagccctcct
    77461 gccctcactt atcagtaaag agtcgccagc aggttacaaa ggtacggcga tgggtgttta
    77521 ctccaccagc cagtttcttg gcgtggcgat tggcggttcg ctgggcggct ggattaacgg
    77581 catgtttgac ggtcaggggg tatttctcgc tggcgcaatg ctggccgcag tgtggctgac
    77641 agtcgccagt accatgaaag aaccgccgta tgtcagcagt ttgcgcattg aaatcccggc
    77701 gaacattgcc gcaaacgagg cgttaaaagt gcgtttgcta gaaactgaag gcatcaaaga
    77761 agtgttgatt gcagaagaag aacattcagc ttatgtgaaa atcgacagca aagtgacgaa
    77821 tcgctttgag atagaacagg caattcgtca ggcataaaaa acgcggcgaa ttgcctgctg
    77881 cgctacgctt atcaggccta caaagtttct gaattacaaa cctttgtagg ccgaatcagg
    77941 cgttcatgcc gcatctgaca tgaacaaaac gcacatagtc gcgattaatc gcggaagttt
    78001 ttgaactgga acggctgacc gagatcgcca ccacgtacca tcgccatgac agcctgcaaa
    78061 tcatcacgag atttgcccgt tacgcggatt tcatcgccct gaatttgcgc ctgcactttc
    78121 agtttgctgt ctttgatcat cttgacgatt ttcttctggg tcgcgctctc aatgccctgt
    78181 ttcagtttcg cttccacaaa ccaggtttta ccgctatgaa cgatattctc cggtacatcc
    78241 agcgaactgc cttcaatgcc gcgcttcagc agcttggcac gcagaatatc cagcaactga
    78301 ttgacctgga aatcggactc gctcaacact ttgatggttt tgctggcgtc gttcagctca
    78361 aatgaggctt caacgttacg gaagtcaaaa cgggactcca cttcgcggct cgcgttatcg
    78421 accgcgttac gtgcttcctg aagatcaact tcagagacaa tatcgaaaga tggcatcttt
    78481 tcctctccct tcatttttga tgcgaagcat aatacccgca aagttaaata accgacagtc
    78541 ctgcaccagg acgtatccct taattgtgca tagtcgcaac agcatgcaca attaagggat
    78601 agccttattg aacacccgga gtggttgcgg gtgaggagga acaatgaaaa ttaccgtatt
    78661 gggatgcggt gccttagggc aattatggct tacagcactt tgcaaacagg gtcatgaagt
    78721 tcagggctgg ctgcgcgtac cgcaacctta ttgtagcgtg aatctggttg agacagatgg
    78781 ttcgatattt aacgaatcgc tgaccgccaa cgatcccgat tttctcgcca ccagcgatct
    78841 gctcctggtg acgctgaaag catggcaggt ttccgatgcc gtcaaaagcc tcgcgtccac
    78901 actgcctgta actacgccaa tactgttaat tcacaacggc atgggcacca tcgaagagtt
    78961 gcaaaacatt cagcagccat tactgatggg caccaccacc catgcagccc gccgcgacgg
    79021 caatgtcatt attcatgtgg caaacggtat cacgcatatt ggcccggcac ggcaacagga
    79081 cggggattac agttatctgg cggatatttt gcaaaccgtg ttgcctgacg ttgcctggca
    79141 taacaatatt cgcgccgagc tgtggcgcaa gctggcagtc aactgcgtga ttaatccact
    79201 gactgccatc tggaattgcc cgaacggtga attacgtcat catccgcaag aaattatgca
    79261 gatatgcgaa gaagtcgcgg cggtgatcga acgcgaaggg catcatactt cagcagaaga
    79321 tttgcgtgat tacgtgatgc aggtgattga tgccacagcg gaaaatatct cgtcgatgtt
    79381 gcaggatatc cgcgcgctgc gccacactga aatcgactat atcaatggtt ttctcttacg
    79441 ccgcgcccgc gcgcatggga ttgccgtacc ggaaaacacc cgcctgtttg aaatggtaaa
    79501 aagaaaggag agtgaatatg agcgcatcgg cactggtttg cctcgcccct ggtagtgaag
    79561 agactgaagc cgtcaccact atcgatctgc tggttcgcgg cggtatcaaa gtcaccactg
    79621 ccagcgtcgc cagcgatggt aacctggcga ttacctgctc gcgcgacgtg aagctgctgg
    79681 cggatgcgcc gctggtcgaa gtggctgatg gcgaatatga cgtgatcgtg ctgcctggtg
    79741 gcattaaagg cgcggagtgt tttcgcgata gcactctgct ggttgaaacc gttaaacagt
    79801 tccaccgttc cgggcgtatc gtcgcggcta tttgcgccgc gccagccacc gtgctggtgc
    79861 cgcacgatat cttcccgatt ggtaatatga ccggcttccc gacgctgaaa gacaaaattc
    79921 ccgccgaaca atggctggac aagcgcgtcg tctgggatgc acgggtaaaa ttgctgacca
    79981 gccaggggcc gggtacagct atcgactttg gtctgaaaat tatcgacctg ttggttgggc
    80041 gtgaaaaagc ccatgaagtg gcatcacaac tggtgatggc ggcagggatt tataattatt
    80101 acgagtagtg tcggatgcgg caaacgtcgc atctgaccag atgcgacgta aaaaccacaa
    80161 attacgggcg atataccttc acattgttaa agccctgctc gcgcagatag agcgcctgca
    80221 gacggctcat caccccgcgc tcacaccaca gcagccaggt tttgttctgg tcgagatcgc
    80281 caaatttggt gctcagttta tagaacggca gagaaaccac atcaatccct tcgactttca
    80341 gtggcttatc ttcctgttca tcgatagaac ggatatcgag gatcacgtcg ttcgggccga
    80401 agccattgac ggtttccact tccaccactt cctgctcggt ctgctgggcg atttcgcgga
    80461 tatcaacgtt attcgcttcc tcaaccactt tatcgagaat gctgaagtcg aacttctctt
    80521 cttccgcttc aatcttcgat ttaactgctt tcaccgtcgg gcttttggag atcacaccac
    80581 aatattccgg catcgtgcga gcaaagtctt cggtgccaat ctggcgggcc aggttgatga
    80641 tgtgctcttt gtcgtaagag atcagcggac gcaggatcag cgtgtcggag acgttatcaa
    80701 tcaggcgcag gttggtcagc gtctggctgg acacctggcc gagcgcttcg ccggtgacca
    80761 gcgcctgtac gccgtaacgt tcagccactt tagatgcggc acgcaccatc atacgtttga
    80821 ggataacgcc catctgaccg tcgtcgattt tctcgagaat ttccccgacg accggttcga
    80881 aattaatagc gacaaaacgc acgcggtggg agctgccaaa gcggttccac agataatgcg
    80941 ccacctgacg cacgccaatt tcatgcgccg cgccgccgag gttaaagaag cagtaatgca
    81001 cgcggcagcc gcgacgcatc aacatataac tggaaacacc ggagtcgaaa ccaccggaaa
    81061 tgagcgacag cacatcttcc tgggtgccga tcgggaaacc gccaatacct tcgtagcggc
    81121 ctttaatcag caggagacga tcgtcttcca cttccagatg gacagtcaca tccggattgg
    81181 tcagcttcac gcgcgcggat tcaatatgct gatttaaacc gccgccgacg taacgttcca
    81241 catcaatcga gctaaaatca tgtttgccac ggcgcttcac gcgtacgcag aaggttttgc
    81301 cttccagctg atcgcgatac tgaaccaacg ctttctcgaa aatatcgtgc atgtcggtaa
    81361 acggcacgtc ttcgacttcg agaatatggt ggatacccgg aatacgggtc agagcgtcgc
    81421 gaatagccag acgctggttt tcatcttttg cgcgaacttc gatgttatcc cagtggcgga
    81481 cgacagcgag cgtctcatca tagtgcttta aaacgttacg aatgttcccg gtaaggattt
    81541 ttataaagcg caagcgcaca gattggcttt tgatggtgat ttccgggaac aatttaatga
    81601 taaacttcat ggcggcaatg gttcgttggc aagccttaag cgacttgtat agggaaaaat
    81661 acagcagccc acacctgcgg ctgcatccag gcgcggaagt ataccactaa catcgctttg
    81721 ctgtgcacat caccttacca ttgcgcgtta tttgctattt gccctgagtc cgttaccatg
    81781 acggggcgaa aaatattgag agtcagacat tcattatgcc gaagaaaaat gaggcgcccg
    81841 ccagctttga aaaggcgctg agcgagctgg aacagattgt aacccgtctg gaaagtggcg
    81901 acctgccgct ggaagaggcg ctgaacgagt tcgaacgcgg cgtgcagctg gcacgtcagg
    81961 ggcaggccaa attacaacaa gccgaacagc gcgtacaaat tctgctgtct gacaatgaag
    82021 acgcctctct aacccctttt acaccggaca atgagtaatg gactttccgc agcaactcga
    82081 agcctgcgtt aagcaggcca accaggcgct gagccgtttt atcgccccac tgccctttca
    82141 gaacactccc gtggtcgaaa ccatgcagta tggcgcatta ttaggtggta agcgcctgcg
    82201 acctttcctg gtttatgcca ccggtcatat gttcggcgtt agcacaaaca cgctggacgc
    82261 acccgctgcc gccgttgagt gtatccacgc ttactcatta attcatgatg atttaccggc
    82321 aatggatgat gacgatctgc gtcgcggttt gccaacctgc catgtgaagt ttggcgaagc
    82381 aaacgcgatt ctcgctggcg acgctttaca aacgctggcg ttctcgattt taagcgatgc
    82441 cgatatgccg gaagtgtcgg accgcgacag aatttcgatg atttctgaac tggcgagcgc
    82501 cagtggtatt gccggaatgt gcggtggtca ggcattagat ttagacgcgg aaggcaaaca
    82561 cgtacctctg gacgcgcttg agcgtattca tcgtcataaa accggcgcat tgattcgcgc
    82621 cgccgttcgc cttggtgcat taagcgccgg agataaagga cgtcgtgctc tgccggtact
    82681 cgacaagtat gcagagagca tcggccttgc cttccaggtt caggatgaca tcctggatgt
    82741 ggtgggagat actgcaacgt tgggaaaacg ccagggtgcc gaccagcaac ttggtaaaag
    82801 tacctaccct gcacttctgg gtcttgagca agcccggaag aaagcccggg atctgatcga
    82861 cgatgcccgt cagtcgctga aacaactggc tgaacagtca ctcgatacct cggcactgga
    82921 agcgctagcg gactacatca tccagcgtaa taaataaaca ataagtatta ataggcccct
    82981 gatgagtttt gatattgcca aatacccgac cctggcactg gtcgactcca cccaggagtt
    83041 acgactgttg ccgaaagaga gtttaccgaa actctgcgac gaactgcgcc gctatttact
    83101 cgacagcgtg agccgttcca gcgggcactt cgcctccggg ctgggcacgg tcgaactgac
    83161 cgtggcgctg cactatgtct acaacacccc gtttgaccaa ttgatttggg atgtggggca
    83221 tcaggcttat ccgcataaaa ttttgaccgg acgccgcgac aaaatcggca ccatccgtca
    83281 gaaaggcggt ctgcacccgt tcccgtggcg cggcgaaagc gaatatgacg tattaagcgt
    83341 cgggcattca tcaacctcca tcagtgccgg aattggtatt gcggttgctg ccgaaaaaga
    83401 aggcaaaaat cgccgcaccg tctgtgtcat tggcgatggc gcgattaccg caggcatggc
    83461 gtttgaagcg atgaatcacg cgggcgatat ccgtcctgat atgctggtga ttctcaacga
    83521 caatgaaatg tcgatttccg aaaatgtcgg cgcgctcaac aaccatctgg cacagctgct
    83581 ttccggtaag ctttactctt cactgcgcga aggcgggaaa aaagttttct ctggcgtgcc
    83641 gccaattaaa gagctgctca aacgcaccga agaacatatt aaaggcatgg tagtgcctgg
    83701 cacgttgttt gaagagctgg gctttaacta catcggcccg gtggacggtc acgatgtgct
    83761 ggggcttatc accacgctaa agaacatgcg cgacctgaaa ggcccgcagt tcctgcatat
    83821 catgaccaaa aaaggtcgtg gttatgaacc ggcagaaaaa gacccgatca ctttccacgc
    83881 cgtgcctaaa tttgatccct ccagcggttg tttgccgaaa agtagcggcg gtttgccgag
    83941 ctattcaaaa atctttggcg actggttgtg cgaaacggca gcgaaagaca acaagctgat
    84001 ggcgattact ccggcgatgc gtgaaggttc cggcatggtc gagttttcac gtaaattccc
    84061 ggatcgctac ttcgacgtgg caattgccga gcaacacgcg gtgacctttg ctgcgggtct
    84121 ggcgattggt gggtacaaac ccattgtcgc gatttactcc actttcctgc aacgcgccta
    84181 tgatcaggtg ctgcatgacg tggcgattca aaagcttccg gtcctgttcg ccatcgaccg
    84241 cgcgggcatt gttggtgctg acggtcaaac ccatcagggt gcttttgatc tctcttacct
    84301 gcgctgcata ccggaaatgg tcattatgac cccgagcgat gaaaacgaat gtcgccagat
    84361 gctctatacc ggctatcact ataacgatgg cccgtcagcg gtgcgctacc cgcgtggcaa
    84421 cgcggtcggc gtggaactga cgccgctgga aaaactacca attggcaaag gcattgtgaa
    84481 gcgtcgtggc gagaaactgg cgatccttaa ctttggtacg ctgatgccag aagcggcgaa
    84541 agtcgccgaa tcgctgaacg ccacgctggt cgatatgcgt tttgtgaaac cgcttgatga
    84601 agcgttaatt ctggaaatgg ccgccagcca tgaagcgctg gtcaccgtag aagaaaacgc
    84661 cattatgggc ggcgcaggca gcggcgtgaa cgaagtgctg atggcccatc gtaaaccagt
    84721 acccgtgctg aacattggcc tgccggactt ctttattccg caaggaactc aggaagaaat
    84781 gcgcgccgaa ctcggcctcg atgccgctgg tatggaagcc aaaatcaagg cctggctggc
    84841 ataatcccta ctccactcct gctatgctta agaaattatt catagactct aaataattcg
    84901 agttgcagga aggcggcaaa cgagtgaagc cccaggagct tacataagta agtgactggg
    84961 gtgaacgaat gcagccgcag cacatgcaac ttgaagtatg acgagtatag caggagtggc
    85021 agcatgcaat acaacccctt aggaaaaacc gaccttcgcg tttcccgact ttgcctcggc
    85081 tgtatgacct ttggcgagcc agatcgcggt aatcacgcat ggacactgcc ggaagaaagc
    85141 agccgtccca taattaaacg tgcactggaa ggcggcataa atttctttga taccgccaac
    85201 agttattctg acggcagcag cgaagagatc gtcggtcgcg cactgcggga tttcgcccgt
    85261 cgtgaagacg tggtcgttgc gaccaaagtg ttccatcgcg ttggtgattt accggaagga
    85321 ttatcccgtg cgcaaatttt gcgctctatc gacgacagcc tgcgacgtct cggcatggat
    85381 tatgtcgata tcctgcaaat tcatcgctgg gattacaaca cgccgatcga agagacgctg
    85441 gaagccctca acgacgtggt aaaagccggg aaagcgcgtt atatcggcgc gtcatcaatg
    85501 cacgcttcgc agtttgctca ggcactggaa ctccaaaaac agcacggctg ggcgcagttt
    85561 gtcagtatgc aggatcacta caatctgatt tatcgtgaag aagagcgcga gatgctacca
    85621 ctgtgttatc aggagggcgt ggcggtaatt ccatggagcc cgctggcaag tggccgtctg
    85681 acgcgtccgt ggggagaaac taccgcacga ctggtgtctg atgaggtggg gaaaaatctc
    85741 tataaagaaa gcgatgaaaa tgacgcgcag atcgcagagc ggttaacagg cgtcagtgaa
    85801 gaactggggg cgacacgagc acaagttgcg ctggcctggt tgttgagtaa accgggcatt
    85861 gccgcaccga ttatcggaac ttcgcgcgaa gaacagcttg atgagctatt gaacgcggtg
    85921 gatatcactt tgaagccgga acagattgcc gaactggaaa cgccgtataa accgcatcct
    85981 gtcgtaggat ttaaataaga gtccaggcct gatgagacgt gacaagcgtc acatcaggca
    86041 tcggtgcaca actacgacag aatacccagc ggccagtgat gaccgataaa atacaggatg
    86101 cctgcggaaa tcaccccggc gacaatatcg tcgatcatga tccccatgcc gccatgcaca
    86161 ttgcgatcaa accagcggat cggccacggc ttccacatat ccagaatacg gaaaatcaca
    86221 aacccggcgg caacccactg ccagtcattg gtcggcagcg ccatgagcgt gatccacata
    86281 ccaataaatt cgtcccagac aatgctgcca tgatcgtgca cacccatgtc tttcgccgtt
    86341 tgatgacaaa gatagacgcc gatacagatc cccagcatca ccaccagcga gtagagctgc
    86401 cagggcaaaa aggtcatcag ataccagaac ggaatcgctg ccagcgagcc catcgtccca
    86461 ggaacgatcg ggcttaatcc acttccgaat ccgacagcaa gtagatgcca cggattactc
    86521 atcttcaggc gacttttcgc gacatcttta tggcgtggca aaatggtcat atcctttcca
    86581 gtctaatgta acaggttcgc cgtcacgaat aaaacaaagc ccttcgatat cggcggtcat
    86641 ttgcccgata caggtaaacg gtacgcccag gtgtccgaga gccacatcca gcgcgccacg
    86701 gttcagttcc ggcacagtga aacacaactc gtaatcttca ccgccagaga gcgcccagcg
    86761 cagcgcctgt tccggttcaa catggcgaga aagcgcatca gaaaacggca gcaatgccag
    86821 gtcaatacgt gcgccgcagt cgctggcttt cacgatatgc ccgagatcgg aaatcaaacc
    86881 gtcagagaga tcgatggctg aatttgccag atcgcgcagt gcctgcccct gtaaaatacg
    86941 cggcgatgga cggagatgac gtttgatcaa gtagtccgca tctttagcat cggcaacctg
    87001 caaacggttt tgcaaaatcg ccagcccggc ggcgctatcg cccggtgtac cggtcacata
    87061 gatccagtca cccggtttcg ccccagagcg cgttaaggct cgtcccatcg gaacaaagcc
    87121 gtggataccc aacgtcattg ataatggccc acgcgtggta tcgccgccaa tgagttgcat
    87181 atcgtaataa ttgagaagat caaacaaact gtcgctgaag gactcaagcc acgcttcgtc
    87241 tacgtccggt aaggttaatg ccagcgtcag ccaggccgga tcggccccca tcgctgccag
    87301 atcgcttagg ttcaccgcca gtgctttata agccagatca gcaggatcga tatcagggag
    87361 gaaatggtta cccgccacca gcgtatcagt gctgatcgcc agggtctgtt tctcggggat
    87421 attgagaagt gcgcaatcgt cgccgatgcc cagttcgaca tcaagacgag aacttcttac
    87481 acggtcaaaa taacgggcaa tcagggagaa ctcgccacat gccatacgtt atgcctcagc
    87541 aggtaaaaaa gaaaaggccg gcgatcatgg aacggtcttc cgtgaatcta ccggcctgga
    87601 tatcactttt tgttagggcg aatcacaggt gctgctttat cgagtacgcc gttgacgaac
    87661 ttatggctgt cttctgcgcc gaacgatttc gccagttcga tcgcttcgtt aatggccact
    87721 ttgtatggca catcgctacg tttagacagt tcgtacagcg caatgcgcag tactgctttt
    87781 tctacctgtc ccagttcttc cagcaggcgg gacaggtatg gcttcatcag tccgtcgagg
    87841 tatgcggtat tagtcgccac cccggccagc agctcacgga agtacaggac gtcaacgtct
    87901 tttacatcct gttcagccag gaactggtat tcaacatcag cgatgtcgtt ctgggacaac
    87961 tgccaggagt agagcgcctg gacggcacac tcacgagcgc ggcgacgagc agcaggtttc
    88021 acggatttcc ccttactaat ttcaggcctt gatggctttc aatacattaa tcatttcaag
    88081 cgcggtcagt gcagcttctg cacctttgtt gccagctttg gtgccagcac gttcgatcgc
    88141 ttgttcaatg ctttcagtgg tcagaacccc aaaagcaacc ggaatttcgc tgtcctgggc
    88201 aacatgcgcc aggccgttgc ttgcaccacc agcgacatat tcaaagtggg cagtgccacc
    88261 acgaataacc gtacccagcg caatcaccgc gtcgtattta ccggttttag ccagtgcacc
    88321 cgccgccagc ggcagctcat aggcaccagg cacccaaaca acggtaatgt tttcatcttt
    88381 tacctgaccg atacgtttca gtgcgtcaat tgcaccttcc agcaggctgt cattgataaa
    88441 gttgttgaaa cgcgcgatgg tgatggcgac gcgagcgtcc ggggtagcaa cgttagcttc
    88501 aataatgttc attttcttcc ttcgggttcg agtatggccc cgcagggggg cggattttag
    88561 cataatattt cgtgcgctgc ttccctttcg agccgggaga tcatgcaccc actaaatgca
    88621 ggcaaacatc cgggcctaca tgacgtatct ctttgaattt aaattggggg gcgtcggcta
    88681 atttctcaag ccctggcagc gtgcataatc cgcgggcgtc gctgcctaat agtttaggtg
    88741 cgatatagac aatcagctca tcgactaaac ccgcctgcag caatgcgcca gcgagcgttg
    88801 gccccgcttc cacccagatg ctgttaattt gctgtttacc cagttgcatc atcagtacaa
    88861 ccagatccag atgaccttta tgctctggaa tcagcaaggt acgcaccgtt tccggccact
    88921 cacgagaatc ttcctgcgta cgcgcgaacc aggtttcgcc gggctgctgc acaatgcgat
    88981 gtaccggcgt cacgcgattt tggctatcaa tcacaatacg tatcggctga cggagatttt
    89041 gttgcggata gagcgcctga gtttgttcat ccagttcaga ccaacgcacc gttaaggcag
    89101 gatcatccgc cagcaccgtg gcgctgctgg ttaaaatggc atgactttgc gcgcgcagta
    89161 gttgtacatc acgccgcgcc tggggcgaag tgatccactg gctttcgccg ctcgccatcg
    89221 ccgtgcgacc atcaagcgat gcgccaagtt ttaactgaat ataaggaaag ccggtgcgca
    89281 tccgcttgag aaagccttta ttcaattgct cggcttcact catcatcagg ccgtggctga
    89341 cgtcaatgcc agcctgttgc agacggtaaa gtccacgccc agcgacctgc gggttaggat
    89401 cttgcatcga ggcaaccacg cgcgctacgc cagcggcgat gagtgcgtca cagcacggtg
    89461 gcgtacgacc atgatggcta cagggttcga gtgtgacata ggcggtcgca cctttggctt
    89521 tttcacccgc catacgcaac gcgtgtactt cggcatgtgg ttcacccgca cgttggtggt
    89581 aaccttcacc gacaatttcg ccatctttga caatgacgca cccgacattc gggttgggat
    89641 gcgtggtaaa acgtcctcgt tgcgccagct ttagcgcccg cgccatgtaa tactcgtcct
    89701 gcacggctta gtcctccagg cgcgcgatct cttcgccaaa ttctttgata tcttcgaaac
    89761 tgcggtagac agaggcaaaa cggatatagg cgactttatc gagctttttc aattgctcca
    89821 tcaccagatt gccaatcatc ttgctcggca cttcgcgctc accggtggcg cgcagctgcg
    89881 atttaatatg attgattgcc atttcgacgt catcggaact caccggacgt ttttccagcg
    89941 cccgcagcat tccgctacgc aatttctctt cattaaacgg ttcacgcacg tcgttgcttt
    90001 ttacaacacg cggcataacc agctccgcca cttcaaaggt ggtgaaacgt tcattacaca
    90061 ccagacactg ccgacggcgg cgtacggatg aaccctcgcc cacgagacga gagtcaatta
    90121 ccttagtgtc cacggcgaaa cagaatgggc aatgcatacg gcgtcctgac caggtggtta
    90181 acggaaatct attttaccct gaactgacga tacaacaaag gcgcaacgct tttgagataa
    90241 aggatcgatg ctttcgctgc ttttaccctc taccattagg ctaattgcga cgagaaaggg
    90301 acgacctatg aatactaacg tttttcgact gctcctgctg ggaagcctgt tcagccttag
    90361 cgcctgtgtg cagcaaagtg aagtgcgaca gatgaaacac agcgtcagca cgctgaacca
    90421 ggagatgacg caactcaatc aagaaacagt caaaatcact cagcaaaaca ggctgaatgc
    90481 aaaatccagc agtggggttt accttctgcc tggagcgaaa acaccggcaa gactggaaag
    90541 ccagatcggt actttacgta tgtcgctggt gaatattacg cctgatgcag atggcaccac
    90601 ccttacacta cgtattcagg gtgagtcgaa tgatcccttg cccgcattca gcggaactgt
    90661 tgaatatggg caaattcagg gaacaataga caactttcag gaaatcaatg tgcagaatca
    90721 attgattaat gcccctgcca gcgtcctcgc ccccagcgat gttgatattc cgttacagtt
    90781 aaaggggatt tctgtggatc agttaggctt tgtacgtatc cacgacattc aacctgttat
    90841 gcagtaaacg tatttcggga cgattttgtg cgtcccgcaa catctttccc cgtcattttg
    90901 ttactctgct tacatcacct ggattgatag taaaagtttg caacaagggc gaaagtcagt
    90961 acaatccccg cccgaatgtg tgtaaacgtg aacgcaatcg attacgtaaa tgatagaact
    91021 gtgaaacgaa acatattttt gtgagcaatg atttttataa taggctcctc tgtatacgaa
    91081 atatttagaa acgcaatttg cgcctttttc actcccgcaa gggattttca aacagtggca
    91141 tacatatgaa aaaaacatta ctggcagccg gtgcggtact ggcgctctct tcgtctttta
    91201 ctgtcaacgc agctgaaaac gacaaaccgc agtatctttc cgactggtgg caccagagcg
    91261 ttaacgttgt cggaagctat cacacccgtt tcggaccgca gatccgcaac gatacctacc
    91321 ttgagtacga agcattcgct aaaaaagact ggttcgactt ctatggttat gcggatgcgc
    91381 cggtattctt cggcggtaac tccgatgcta aaggtatctg gaaccacggt tctccgctgt
    91441 ttatggaaat cgaaccacgt ttctccatcg acaagctgac caatactgac cttagcttcg
    91501 gtccgttcaa agagtggtac ttcgcgaaca actacattta cgacatgggt cgtaataaag
    91561 atggtcgcca gagcacctgg tacatgggtc tgggtaccga tatcgacact ggcctgccga
    91621 tgagcctgtc catgaacgtc tatgcgaaat accagtggca gaactatggc gcagcgaacg
    91681 aaaacgagtg ggacggttac cgtttcaaaa ttaaatactt tgtgccgatt accgatctgt
    91741 ggggcggtca gctgagctac atcggcttca ccaacttcga ctggggttcc gatttagggg
    91801 atgacagcgg taacgcaatc aacggtatta agacccgtac taataactct atcgcttcca
    91861 gccatattct ggctctgaac tacgatcact ggcactactc tgtcgtagct cgttactggc
    91921 acgacggtgg tcagtggaac gacgatgcag aactgaactt cggcaacggc aacttcaacg
    91981 ttcgctctac cggctggggt ggttacctgg tagtaggtta caacttctga ttatgaaaat
    92041 gccgggattt attcccggca tttctgattg ttaacaacgt gtgctttgtt catgccggat
    92101 gcggcgtaaa cgctttgtcc ggccaacaaa agcacgtaaa ttcaatatat tgctgaaata
    92161 acgtaggcct gataagcgta gcgcatcagg caattttacg ttttaatcac ttcttcttgt
    92221 tcatcatcgc tttcaggtca gcgaatgggt tgtacttcgc ttcaccgaca tctttctgcg
    92281 catcttcccc tgcgataacg gtcgtaccat actgatccgc ttcggtatat ttcgaatgct
    92341 catgatcgtg gcaatagaga cacaacaatt cccagttact gccatcttcc gggttattgg
    92401 tatggccgtg atcaatgtgg tgaacggtaa gttcacgcag gttggaataa acaaactcgc
    92461 gggaacagcg accgcagacc cacggataga tttttaatgc tttttcgcga tagccgcttt
    92521 ctaaccgcgc atagtttttt gggatgatag ccatgaaaag ttacctggat gaaatgtagg
    92581 gttacgcgca gtttcccaag atgcggggat tttcgcaatc tccatacatc aaaaaaaatc
    92641 ccgatcttct gaccgggatt ttcaacatca acgggaactt gattacggca gaattgacgg
    92701 ctgatccgcc ccttcttttt ccactttctg ctgcaacatg tgttcgcgct tcatacccag
    92761 tttcagagcc aacgcagatg ccacatagat ggaagatgca gtaccgatgg aaacaccgat
    92821 aagcatggtc agcgagaagc cttccagtac cggaccaccg aagaggtaca gcatcaggat
    92881 aaccatcaag gtagtaccgg atgtgatcaa ggtacggtgc agcgtctggg tcaaggacac
    92941 gttaaagatt tcgtaaggcg taccgcgacg gatcttgcgg aagttttcac gaatacggtc
    93001 cgataccacg atactgtcgt taagcgagta accgataacc gacatcaacg atgccacaat
    93061 ggtcaggtca atctcgatat ggaataacga caaaataccc agcgtaatga taacgtcgtg
    93121 cgccagcgca ataaccaccc ctgccgccag tcgccactca aagcggaaac ctacgtacac
    93181 gaggatagac agcagcgctg ccatcaacgc catcgcaccg gtttgcgcaa ggtctgcccc
    93241 cacgctcgga ccgacgaact caatacgctt cactgctgca ttctgattgg tggattcgtt
    93301 aatcaccttc agaacctggc tgcccaacac ctgaccgccg gtttcgcctt cagcaggcgg
    93361 catacggacc atgatgtcat ggctgctacc aaagttttgc agcatcggct cttcaaaacc
    93421 ggctttttgc aatgcatcac gcattacgtc aatttcagcc ggtttttcga gcgtaatttc
    93481 aataaccgta ccaccggtga aatccagccc ccagttaaag ccgcgcacgc ccataataac
    93541 gatagcagcg attaacagca gaccagagat gccgaaagcc cagtagtccc agcgcataaa
    93601 gtcatagact ttacggccgt ggtttagttg ttcaacagta tattcctgtg ccacatcgca
    93661 ctcctcagat tgacagcttc ttgacgcgct tgccgccata tagcaggttt acgatggcac
    93721 gcgtaccgac aatcgcggta aacatcgacg tcgccacacc gataccggta gtaatcgcga
    93781 accctttaat tgccccggta cccactgcgt acaggatgat gactttaatc agcgtggtga
    93841 tgttcgcatc gaagatagaa ctgaatgcgc cacgataacc ttcatcaatt gcctgttgaa
    93901 cagtacgtcc gttgctcaac tcttctttaa tacgttcgtt gatcagtacg ttcgcatcga
    93961 ccgccaccgc aagggttaag acgatacccg cgatacctgg catactcagc gttgcgcctg
    94021 gcaacagcga cataatgccg acgattaaga tcaagttggc aatcagagca ctggtcgcaa
    94081 tcagaccaaa cttcttatag aagatgatca tgaacagaat agaaaccagc agaccggcaa
    94141 ggcaagcctc cagcccctgt tcaatgttct gcatacccag ggttgggcca atggtacgtt
    94201 cttcaacaat ctgaatcggc gcgatcaacg caccggcacg cagcagcagt gacagctgac
    94261 gggcttcgtt cgggttgttg atgccggtga tacggaagct gttacccaga cgagactgga
    94321 tgttggcgat gttaatcacc tcttcctgtt tcaccagaac cgcacgacca tttgcatctt
    94381 tcttaccgct gtctttgtac tccacaaaca gggttgccat cggtttgccg atgttgtcct
    94441 tagtgaagtt agacatgatg ttaccaccag cgctatcgag cgagatgtta acctgcggtt
    94501 ggttgtattc gtcctggctg gaagtggagt cggtgatatg gtcaccggtc agaattacgc
    94561 gtttgtacag cacaactggc tgaccttcgc gggtctgttt cacttcagag tcgcccggta
    94621 cgcgaccgga tgccgcagcg gcctggtcaa cgttggtgtt taccagacgg aattccagcg
    94681 ttgccgtcgc acccagaatc tctttcgcac gcgcagtgtc ctgaatacct ggcagttcaa
    94741 caacgatacg gtcagcaccc tgacgctgaa ccaccggctc cgccacgcca agttggttta
    94801 cacggttacg caggatatta atgttctgct gcaccgcata ttcacgcgct tcactcagac
    94861 gagcatcgct cattaccgca cgcagctggt tgctgccctg gctgctaatc accaggtccg
    94921 gatggcgctt gctcagatac gcaatggctt catcacgagc tttagcatcg cggaaagtga
    94981 tgctcaggcc gtagttgttt tctttacgaa cagtggtata cgggatgccc ttttcgcgca
    95041 ggtcactgcg taggctatcg atattttgtt cctggagttt gccaagcgcg gtgtccatat
    95101 ccacttccat caggaagtga acgccgccac gcaggtcaag gccgagcttc atcggctcag
    95161 cgtgaatagc tgccagccag cgcggcgttg ccggggcaag gttaagcgcc acgacgtatt
    95221 tgtcacccat aacgcccatt aatgcttcac gagcgcgcaa ctgggtgtca gtggagtcga
    95281 agcgcgcaag aatagcgccc tcttccagtg ccacagactt agcagttatt ttttcttctt
    95341 gtaacgtttt ctggacctgg atcagcgttt gctcactggc ggcgactccg cgcgcaccag
    95401 tgatctgaac agccggatcc tcaccaaaca ggttgggaag cgcatacagc agaccgatga
    95461 caatcaccac gatcagcatg acgtacttcc acaaaggata acggtttaac acggcaattc
    95521 ccttagggaa aaattttaat tacagcgcct tcatggtgcc tttcggcagg acggcagcta
    95581 cgaagtcacg tttaataact acttcagtgg tgtcattcag cgcgatagca atgtagccgt
    95641 tttccgctac tttggttacg cgaccaacca ggccaccgtt cgtcagaact tcatcacctt
    95701 tggcaatgga gtccatcagc tttttgtgtt ctttggtgcg cttctgctgt ggacgcagga
    95761 tcatgaaata gaaaatcaga ccgaatacca ccagcatcaa aatcaaagac atcgggctac
    95821 cttgcgccgg tgcacccgtt gccgctaccg catcagaaat aaaaaagctc attaaatttc
    95881 cctcattatt aatattaatc aacgttcaaa ggtggtactt ctcgcccctg acgctggtaa
    95941 aaatcagtta ctaagctctc taatttaccc tcttcaatag ccttgcgtaa acccgccatc
    96001 aaacgctggt agtaacgaag gttatgaatg gtgttgagtc gcgcgcctaa tatttcgttg
    96061 caacggtcaa gatgatgcaa gtaagcgcgt gaataattgc gacaggtgta gcaatcacac
    96121 tcaggatcga gtgggccagt atcgctctta tacttcgcat tgcggatttt caccacgcca
    96181 tcggtcacga acaaatgacc atttcgggcg ttgcgggttg gcattacgca gtcaaacata
    96241 tcgataccac gacgtacgcc ttcaaccagg tcttctggtt taccaacgcc catcaggtaa
    96301 cgcggtttgt ctgccggaat ttgcgggcat acatgctcca gaatgcggtg catatctgct
    96361 ttcggctcac ccacagccag accgccgaca gcgtagccat caaaaccgat atctaccaga
    96421 cctttaacag aaatatcacg taaatcttcg taaacgctgc cctggatgat accaaacagc
    96481 gcatttttgt ttccgagact gtcaaaacgc tcacggctac gcttcgccca acgcagagac
    96541 atctccatgg agcgttttgc gtaatcccag tcagcaggat acggcgtaca ctcatcaaag
    96601 atcatgacga tatccgaacc aagatcgtac tgaatctcca ttgatttttc aggatcgagg
    96661 aaaatcggat cgccgttgat cgggttacgg aagtgcacgc cctgttcggt gattttacga
    96721 atatcgccaa ggctgaagac ctggaagccg ccggagtcgg tgaggatcgg ccccttccac
    96781 tgcataaaat cgtgcagatc gccgtgcagt ttcatgattt cctggcccgg gcgcagccac
    96841 aggtggaagg tgttgccgag gataatttgc gcgccagtgg cttcaacttc ttccggcgtc
    96901 atccctttta cggtgccgta ggtgccaaca ggcataaaac aaggcgtttc cactacgcca
    96961 cgatcaaaga ccaggcggcc acggcgtgcg cgaccgtcgg tggtgtccag ttcaaatttc
    97021 attttttctc cactacgtca gaaaaacagt ccaacgtttt aaaccagcgc cgcggaatta
    97081 ctccccgacg cgctcattaa ttgcctgcgg attgtacgtg ataaacatcg catcaccgta
    97141 actaaaaaag cgatatttct cttctaccgc tgctttatag gcgttcatgg tgtgttgata
    97201 accggcaaag gccgaaacca gcataatcag cgtcgactct ggcaagtgga agttcgtcac
    97261 cagcgcatcg accactttgt actggaagcc cggatagata aagatttggg tatcgtcgaa
    97321 gaacggttca atgagatcgt ttttcgctgc ctgagccgcg ctttccagcg aacgtactga
    97381 agtggtgcca accgcaatca cccggttacc gcgcgctttc gccgccagta ccgcgtctac
    97441 cacatcctgc ggtacttcag cgtattccga gtgcatgatg tgatcttcaa tggtgtcgac
    97501 gcgcaccggc tggaaggtgc ccgcaccaac gtgcaacgtc acaaacgcca tctccacgcc
    97561 tttggcgcgc aatttttcca gcaaaggctc gtcaaaatgc agacctgcgg tcggggctgc
    97621 aaccgcgccc ggtttttcgc tataaacggt ttgataaagt tcgcggtcag cgtcttcgtc
    97681 cggacggtcg atatacggcg gcagcggcat atggccgatg ctgttgagaa tatccagcac
    97741 cgagcgttca tcattaaatt cgacttcaaa cagtgcgccg tggcgcgcgg tcattgttgc
    97801 gttaatactt tcgtcatcgc ccagcagcag ttctgcgcca ggttttggcg ctttcgaggc
    97861 gcgaatatgc gcaagaatgc gtttgtcgtc gagcatccgt tcaaccagca cttcaatctt
    97921 gccgccgctg gctttacgcc caaacaggcg cgccgggatc acgcgggtat tattaaaaac
    97981 cagaagatcg ccggggttga gcttatcaag taaatcggtg aaagtaccgt gcgtcagcgc
    98041 gcccgtcggc ccgtccagcg acagtaaacg acagctactg cgttcaggca tgggatagtg
    98101 ggcaatcagg gattcgggca attcaaagga gaaatcggta acgcgcatga cactgactca
    98161 gactaaaata agaggcgggt agtctagtgc cggggcgctc tccctgcaac ctttaccccc
    98221 ttttggatag aatataatcg atgaattttt tagctcacct gcatttagcc catctcgcgg
    98281 aaagctcgct ttccggcaat ttactggctg atttcgtacg cggaaatcct gaagaaagtt
    98341 ttccgcccga cgtcgtggct ggcattcata tgcatcgacg tatcgacgta ttgactgaca
    98401 atctgccgga agtccgcgaa gcacgggagt ggtttcgtag tgaaacgcgc cgcgttgcgc
    98461 ctattacgct ggatgtcatg tgggatcact ttctttcccg ccactggtcg cagctgtcgc
    98521 cggactttcc gctacaggaa tttgtctgtt atgcccgcga gcaagtgatg acgattttgc
    98581 cggactcacc gccacgtttt atcaatctga acaattactt gtggtcagag cagtggctgg
    98641 tgcgctatcg cgatatggat ttcatccaga acgtgttaaa cggcatggca agccgccgcc
    98701 cacgtctgga tgccctgcgt gactcctggt acgatttaga cgctcattat gacgccctcg
    98761 aaacccgctt ctggcagttt tatccgcgga tgatggcgca ggcgtcacgc aaggcgttat
    98821 aaaacgttag ttcatccata ccgtagccga aatggcaggc aaagccagaa tcccgtcagt
    98881 cagttgccca tgcccttctt tgcattgcca ttgcacggca ttgagaaacg gtgacgcggg
    98941 tagcaccact tcacaggcct cgccacggtt gattgccacc agtacacgtt gctgattcag
    99001 cacgcggaca aataccacca cgttatcttc cgcatacagc acctgacagc cgccatgacg
    99061 tagcgcctga cttttcttac gcagcgcaat cattcgctgg tacagcgcga ataacgccgt
    99121 atcctgcttt tccacctgcc aggggaacgg tttacggcaa aacggatcgt ttttgccatc
    99181 cagtcctact tcatcaccgt aataaatgca cggtacacca ggccaggtga acagccagac
    99241 caccgccagc ggcaggcgcg caatatcccg accgagcagc gttttaaatc gcgcagtatc
    99301 gtggctgtcg agctgattaa acatacgtaa ttgttgttga tgagaaagcc ctgcgcggta
    99361 attatccatc caggccatac aggtttgggc atcaatttgc tgcggatcgt aagagatatc
    99421 ggtattggca agaaatcccc acaacgggaa tgtgaagcca cgatagttca tggcggcatc
    99481 ttccacatcg gcctgtaacc attgccgtgc atcgccaaaa tgttcgccga caatatacgc
    99541 ttccggctgg gtttctttcg ccgcttcggt gatcccggca acgtgctgca tattattgcg
    99601 cgccccaccc gcctccccca gcatatgcac cacatccagc cgccagccgt ccatattcca
    99661 cggcgctttc agccagtggc ggacaatact gtcttccccg cgataaattt cattcaccag
    99721 actttccgac tgataatcca gcttcggcaa gctggcatag ccaagccagt cgagcgccgt
    99781 gccatcatca ctaaacgagt accagtcgcg ccagggcgat tcggggttgt gacaagcacc
    99841 acccgtgcca cgattatgcc tgtcaaacca ggcatgggaa tcgccactgt ggttaaacac
    99901 gccgtccagc accagccgca ttcccagctg ctgcgtattg tgtcgcaaac gcagcaacgc
    99961 cccatcaccg ccaaactgcg gatcgacatg gcgataagcc tcggtatcgt atttatgtac
   100021 gctgggagct ttaaacaccg gattgagata cagcgctgtc acgccaagct ttttcagata
   100081 cggcagtttt tcgcttatcc cgtccagatc gccgccatag aacgttgatc cgcccgcctg
   100141 cgccgtgacc ggttcatccc agtcacgcaa gatgatctct tgtccggctg catgatggta
   100201 atagacatga tcctgttcag cttcacgagg aagactacgc gcaaaacgat cagggaagat
   100261 ctgataaaaa atctgatccg cagcccattg tgggccgata tccggtacat cgacggcaaa
   100321 ctgctccagt cgtgccggcg gcattcggct gaagccctgc ggtgtaaacc aacgctggcg
   100381 atcgtgccac agcagtttga aactgtaacg ccgccggggt tgtccgctgg agagatcaat
   100441 cgccgcacgc catgcggtga cgccaggctg cggctgactg cgctgcttat gcatcggtac
   100501 tgacatttct tcgttatcgt gttctgtacg cagcataatg cgctgcggtg ggtcttcgcc
   100561 cgtcagccac agtgtaatga gcagttgatc tttgctttgt ttaacaaatg ggggcaccgg
   100621 caggtgccat gcatttaaca tcataattcc cctgtgatga aaatctgatc accttgccat
   100681 agcctaatgc aggatcactc atcatctgaa ggatatttgg gggaggagga cgggggcgga
   100741 taactttcgg aatagccgga tcaggatttc ctcctgaacc ggcttacaga acgcaaggat
   100801 tactggtttt cagccagctg acgatcgtgg cggcgtttaa acatccagcc aatcaacagc
   100861 acaacaatcc acgcgaaacc gacatacagc gagatacgcg tatccgggtg ataaccaatc
   100921 aacccgataa taaagagcag gaaaatcagc ccgccgatgg tcgttgctac cccacccggc
   100981 actttaaatt tcagcgcctt aacttcttct ggcggcaaac ggcgacggaa ggcaatttgc
   101041 gacagcagga tcataatcca cacccacacc gtggcgaagg ttgccagcga agcgatcacc
   101101 aggaagacgt tttccggcat gatgtagttc agatacaccg caaacagcag cgcggtagtc
   101161 atcaccagca ccgtaaccca cggaataccg cgacgcgacg ttttgctgaa aattttcggc
   101221 gcgctgccct gctctgccat accgtggagc atacggccta cgccaaatac atcactgtta
   101281 attgccgaca gcgaagcagt cagcacaaca aagttaagaa tgctggcggc aaaggtaatg
   101341 cccatatgct ggaacgtcag cacgaacggg ctaccggcag tgccaacctg attccacggg
   101401 tagatagaca taatgacgaa cagcgtaccg acgtagaaca ccagaatacg catcggcacg
   101461 gagttaatcg cacgcggtat cgatttctca ggatctttcg cttcaccggc ggtaatcccg
   101521 ataatttcga tcccaccgta agcaaacatc accatttgca acgacattac catgccaagc
   101581 cagccgttac tgaagaagcc gccgttgctc cacaggttat gaataccggt cggttgcccg
   101641 ccgttgccaa tcccccagat gatgatgccg aaaccggcga caatcatgat gatgatggtg
   101701 gcgactttaa agaacgagaa ccagaattcc agctcaccga ataccttcac gctcatcagg
   101761 tttacggcgc aaatgatcag caccacgctc agtacccaaa tccagtgcgg caccgtcggg
   101821 aaccagacac ccatatagat accaaaagcg gtcacatcgg cgatggcgac aataaggatt
   101881 tcaaagcagt aggtccagcc ggtaatgtaa cctgccagcg ggccgaggtt ttcctgcgca
   101941 taacgcgaga aagagctggc ggccgggtta tgtaccgaca tttcccccag cgcacgcata
   102001 atgatatacg ccgcgatacc accgataata taggccaaca acacgctcgg accggccatt
   102061 ttgatggcgt ctgccgaacc gtaaaacagc ccggtgccaa ttgctgaacc cagtgccata
   102121 aagcgtatgt ggcgggtact tagcccacgc tttagcttgt tcttactttc catcaattcc
   102181 taacccatca acacaataaa aaaccacggg gcatcgcagc cccgtggtta aaacaaatgt
   102241 tcagtgattt agtgagcgct ggaggtcacc tgacgacctg ccgcgcgatc ccagataatg
   102301 gccagaacca ccatcaccac tgttggcatt aaccacgcca gaccttgttc ggccagcggt
   102361 aaacgctgcg cccaggacgg taagatatcg ctgaatgcag atgctttgat cccgtcgaga
   102421 ataccaaaaa gcaggctgat aaacatcggc ggagcaatca cgcgggacga attatgccac
   102481 catgagcgtg taaaacttaa tacaaccagt gcgatacacg gcggataaat agcggtcagc
   102541 accggtacgg agatctggat cagctggctt aagccgaggt tagaaaccac catcgagaag
   102601 ccgccgagga taaacaccag cgtacgataa gagagcggta cgtactgggc aaagaattct
   102661 gcacaagcac aggtcaggcc aactgccgtt accaggcagg cgatgaagat taacgccgcc
   102721 agcaggaagc taccgccgcc gccaaaggtg tgctgaacgt aagcatgcag aatagcagcg
   102781 ccgtttgcag actgatcgac cagcgacgcg ctgtctgacc ccagacggaa cagcgccagg
   102841 tacagcagag tcagaccaac acccgccatc aggccagccc agacggtata acgggtcagc
   102901 agacgcgctt cggtaacgcc acgagaacgc gccgcgttaa caataacgat accaaacacc
   102961 attgcgccca gcgtatccat ggtcagatag ccgttaacga agccgttaga aaacgcagcg
   103021 ttttgataag cctcagtcgc cgtgctgata gaacccgccg gccagacaat agcggcaaca
   103081 gacaggatga ccagcgcgat aattttcagc ggcgcaagga agttgcccac ggtatccagc
   103141 agcttgcccg gatagagcga aaccagaata acgatagcga aatagaccag gctgtagata
   103201 aacagcggca gcgcggaatc acccgtcagc ggcgcaatcc ccacttcaaa ggaaacggta
   103261 gctgtacgcg gcgtagcgaa aagcggcccc accgccaggt aacaaaccgt tgccagcagt
   103321 acgccagcga ctttaccgat tggcgtgctg aggctgtcaa caccgccgcc aacttttgcc
   103381 agcgccacta ccgttaatac cggcaggcca acggcagtaa tgaggaagcc gaatgccgca
   103441 gtccagacgt gttcgcctgc ctgtaagccg accattggag ggaaaataat gttacctgcg
   103501 ccgacgaaca acgcaaatgt cataaagccc agagcgatga tatcgcgcga tcttaattga
   103561 tgggtcataa atcatactgc ctgtggatgt ggtgttgtaa cgttaaattt ttgtgccaat
   103621 ccctggggat gatacagcgg tatatttaaa caattttagc gggaaatact cccaaccagg
   103681 cgcggcgaag aatagttttt cgatttaccg cgttaatgca gtcagtatga cagcacctga
   103741 agcgcaattt aaacgcttat aacgttttaa agcaaggagg gatctaaaaa ccagaggtat
   103801 atagcgataa gaaatcacca accagtataa aacactattt ccgtgaaaaa gacatggcta
   103861 atcatgcgaa caaaaaatca ccaaccgttg taaaatctaa cgcccgtatt ttgactgcaa
   103921 agaaaataag ccagcatcga ctggcttatg gcaataaaag atgacaaagg cggattaatc
   103981 gctgtttttg gcaattaaac gttccgggat aacaaaactg aaacgtgttc cttttcctac
   104041 tgtactctca atattcaggc gactttcgtg atgattcaca gcatgtttca cgatcgctaa
   104101 ccctaatccg ctaccgccgg tttgccggga acgcgcttta tcaacgcgat aaaaacgctc
   104161 ggtcaggcgc ggaatatgct ccggtgcaat gcccggtccg ttatcttcaa cgctaaattc
   104221 ggcaccgtgc ggcactcgct gccagcgtac ggtgatatgc gtgccttccg gcgtatgatt
   104281 cacggcgtta tagaccaggt tcgaaatcgc actgcgtagc tgatcttcgt tgccagacac
   104341 cttgaggccg ttatctatct caaaggtaaa tgtctgtttt ttctgactca gagtctgagc
   104401 ctcgcgctca acaacgcgca gcatcatcgg cacatcaacc ttttcattga gcaaatgcgt
   104461 cggtgcggct tctattttcg acagcgtcag caattgcttc accagtcctt ccatccgctg
   104521 ggtctgctcg cgcatggtgt gcaacgcttt ttcgcgtacc gcgccttcca gcggctgctc
   104581 attcatcatc tccaggtaac cctgtaacac ggtcaatggc gtacgtaact catggctcac
   104641 gttggcaaaa aagttacgcc gcgccccttc cagttgatgc atttgcgtga catcacgcgc
   104701 caccatcagc aactgtttgt gggtataagg catgacgcga atttccagat gccgcccggt
   104761 gttgagcacc agattgagcg ggcgagaaaa atcacgcgtt ttcagatatt gcgtaaactc
   104821 cgggtaacgc agtaggttaa ggatgttctg cccgttatct tccggccagc gcaaaccaag
   104881 aatttgttgc gccagaccgt tacaccagaa aataccgccc tcttccgtgg tcagcaccac
   104941 cgcgtcgggc agcgactccg cgccgctacg aaagcgttta atcagattgc ccagttcacg
   105001 gcggcgtttt ttatttcgca gctgcatctg gtgtaagccg tatagtagcg gttcccagct
   105061 accacgcccc ggtggcgggg tcatactgcg atccacccac agccaccatg aaaggcgcaa
   105121 taaattccag aaatgccaga taagcagtcc tgttaccgat gccagcaaaa accagggcag
   105181 gtaaccaaaa aatgcaccca ggatgaaagc cgggaggcag caaagtagca gctccagcac
   105241 cagccttttc cacgacagcc gttccagcac gtaagatact ccagttaaga aatcataagc
   105301 cctgctctgc gtccgatgag caaggcgtta aaagcgggtt gaaaaacgat atcctgtacc
   105361 gcgcacggtc tgcaccatgc ggtcatgccc gccgggctcc agtgctttac gcaggcgacg
   105421 aatgtggaca tcgaccgtgc ggtcttccac atacacgtta gttccccaga cgtggtttaa
   105481 cagctgctcg cggctgtaca cgcgctcagg atgcgtcata aaaaagtgca gcagtttaaa
   105541 ttctgtcggc cccatctcca gcggctcttc gcccgccatc actcggtgag atgtcgggtc
   105601 gagacttaat ccctgcatct caatcacctc ttccaccgcc attggcgaaa tacggcgcat
   105661 taccgctttg attcgcgcca ccagctcctt cggcgaaaac ggcttggtga tatagtcatc
   105721 cgcgccggtt tcaaggccgc gcacgcgatc ttcttcttcc cctctggcgg tcaacatcac
   105781 cactggaata tcccgggtca tcgactcgcg cttgaggtgt ttgatgaact ggataccgga
   105841 gccgccaggt aacatccagt cgaggagaat taaatccggc cagggttcat tcagttgatt
   105901 cacagcactg tcataatctt ccgcttcgac cggctgaaag ccattttgtt cgagcacgaa
   105961 gcagaccatt tcgcgaattg gagcttcatc ttctacgacc agaatacgtc tcgccatgat
   106021 ttgccctgtt gtaataaata ggttgcgatc attaatgcga cgtcattatg cgtcagattt
   106081 atgacagatt tatgaaaagc tcgtcgcaca tatcttcagg ttattgattt ccgtggcgca
   106141 gaaaaaagca aatggcacat ctgtttgggt ataatcgcgc ccatgctttt tcgccaggga
   106201 accgttatgc gcatccttca cacctcagac tggcatctcg gccagaactt ctacagtaaa
   106261 agccgcgaag ctgaacatca ggcttttctt gactggctgc tggagacagc acaaacccat
   106321 caggtggatg cgattattgt tgccggtgat gttttcgata ccggctcgcc gcccagttac
   106381 gcccgcacgt tatacaaccg ttttgttgtc aatttacagc aaactggctg tcatctggtg
   106441 gtactggcag gaaaccatga ctcggtcgcc acgctgaatg aatcgcgcga tatcatggcg
   106501 ttcctcaata ctaccgtggt cgccagcgcc ggacatgcgc cgcaaatctt gcctcgtcgc
   106561 gacgggacgc caggcgcagt gctgtgcccc attccgtttt tacgtccgcg tgacattatt
   106621 accagccagg cggggcttaa cggtattgaa aaacagcagc atttactggc agcgattacc
   106681 gattattacc aacaacacta tgccgatgcc tgcaaactgc gcggcgatca gcctctgccc
   106741 atcatcgcca cgggacattt aacgaccgtg ggggccagta aaagtgacgc cgtgcgtgac
   106801 atttatattg gcacgctgga cgcgtttccg gcacaaaact ttccaccagc cgactacatc
   106861 gcgctcgggc atattcaccg cgcacagatt attggcggca tggaacatgt tcgctattgc
   106921 ggctccccca ttccactgag ttttgatgaa tgcggtaaga gtaaatatgt ccatctggtg
   106981 acattttcaa acggcaaatt agagagcgtg gaaaacctga acgtaccggt aacgcaaccc
   107041 atggcagtgc tgaaaggcga tctggcgtcg attaccgcac agctggaaca gtggcgcgat
   107101 gtatcgcagg agccacctgt ctggctggat atcgaaatca ctactgatga gtatctgcat
   107161 gatattcagc gcaaaatcca ggcattaacc gaatcattgc ctgtcgaagt attgctggta
   107221 cgtcggagtc gtgaacagcg cgagcgtgtg ttagccagcc aacagcgtga aaccctcagc
   107281 gaactcagcg tcgaagaggt gttcaatcgc cgtctggcac tggaagaact ggatgaatcg
   107341 cagcagcaac gtctgcagca tcttttcacc acgacgttgc ataccctcgc cggagaacac
   107401 gaagcatgaa aattctcagc ctgcgcctga aaaacctgaa ctcattaaaa ggcgaatgga
   107461 agattgattt cacccgcgag ccgttcgcca gcaacgggct gtttgctatt accggcccaa
   107521 caggtgcggg gaaaaccacc ctgctggacg ccatttgtct ggcgctgtat cacgaaactc
   107581 cgcgtctctc taacgtttca caatcgcaaa atgatctcat gacccgcgat accgccgaat
   107641 gtctggcgga ggtggagttt gaagtgaaag gtgaagcgta ccgtgcattc tggagccaga
   107701 atcgggcgcg taaccaaccc gacggtaatt tgcaggtgcc acgcgtagag ctggcgcgct
   107761 gcgccgacgg caaaattctc gccgacaaag tgaaagataa gctggaactg acagcgacgt
   107821 taaccgggct ggattacggg cgcttcaccc gttcgatgct gctttcgcag gggcaatttg
   107881 ctgccttcct gaatgccaaa cccaaagaac gcgcggaatt gctcgaggag ttaaccggca
   107941 ctgaaatcta cgggcaaatc tcggcgatgg tttttgagca gcacaaatcg gcccgcacag
   108001 agctggagaa gctgcaagcg caggccagcg gcgtcacgtt gctcacgccg gaacaagtgc
   108061 aatcgctgac agcgagtttg caggtactta ctgacgaaga aaaacagtta attaccgcgc
   108121 agcagcaaga acaacaatcg ctaaactggt taacgcgtca ggacgaattg cagcaagaag
   108181 ccagccgccg tcagcaggcc ttgcaacagg cgttagccga agaagaaaaa gcgcaacctc
   108241 aactggcggc gcttagtctg gcacaaccgg cacgaaatct tcgtccacac tgggaacgca
   108301 tcgcagaaca cagcgcggcg ctggcgcata ttcgccagca gattgaagaa gtaaatactc
   108361 gcttacagag cacaatggcg cttcgcgcga gcattcgcca ccacgcggcg aagcagtcag
   108421 cagaattaca gcagcagcaa caaagcctga atacctggtt acaggaacac gaccgcttcc
   108481 gtcagtggaa caacgaaccg gcgggttggc gtgcgcagtt ctcccaacaa accagcgatc
   108541 gcgagcatct gcggcaatgg cagcaacagt taacccatgc tgagcaaaaa cttaatgcgc
   108601 ttgcggcgat cacgttgacg ttaaccgccg atgaagttgc taccgccctg gcgcaacatg
   108661 ctgagcaacg cccactgcgt cagcacctgg tcgcgctgca tggacagatt gttccccaac
   108721 aaaaacgtct ggcgcagtta caggtcgcta tccagaatgt cacgcaagaa cagacgcaac
   108781 gtaacgccgc acttaacgaa atgcgccagc gttataaaga aaagacgcag caacttgccg
   108841 atgtgaaaac catttgcgag caggaagcgc gcatcaaaac gctggaagct caacgtgcac
   108901 agttacaggc gggtcagcct tgcccacttt gtggttccac cagccacccg gcggtcgagg
   108961 cgtatcaggc gctggagcct ggcgttaatc agtctcgatt actggcgctg gaaaacgaag
   109021 ttaaaaagct cggtgaagaa ggtgcgacgc tacgtgggca actggacgcc ataacaaagc
   109081 agcttcagcg tgatgaaaac gaagcgcaaa gcctccgaca agatgagcaa gcacttactc
   109141 aacaatggca agccgtcacg gccagcctca atatcacctt gcagccactg gacgatattc
   109201 aaccgtggct ggatgcacaa gatgagcacg aacgccagct gcggttactc agccaacggc
   109261 atgaattaca agggcagatt gccgcgcata atcagcaaat tatccagtat caacagcaaa
   109321 ttgaacaacg ccagcaacta cttttaacga cattgacggg ttatgcactg acattgccac
   109381 aggaagatga agaagagagc tggttggcga cacgtcagca agaagcgcag agctggcagc
   109441 aacgccagaa cgaattaacc gcgctgcaaa accgtattca gcagctgacg ccgattctgg
   109501 aaacgttgcc gcaaagtgat gaactcccgc actgcgaaga aactgtggta ttggaaaact
   109561 ggcggcaggt acatgaacaa tgtctcgcat tacacagcca gcagcagacg ttacagcaac
   109621 aggatgttct ggcggcgcaa agtctgcaaa aagcccaggc gcagtttgac accgcgctac
   109681 aggccagcgt ctttgacgat cagcaggcgt tccttgcggc gctaatggat gaacaaacac
   109741 taacgcagct ggaacagctc aagcagaatc tggaaaacca gcgccgtcag gcgcaaactc
   109801 tggtcactca gacagcagaa acgctggcac agcatcaaca acaccgacct gacgacgggt
   109861 tggctctcac tgtgacggtg gagcagattc agcaagagtt agcgcaaact caccaaaagt
   109921 tgcgtgaaaa caccacgagt caaggcgaga ttcgccagca gctgaagcag gatgcagata
   109981 accgtcagca acaacaaacc ttaatgcagc aaattgctca aatgacgcag caggttgagg
   110041 actggggata tctgaattcg ctaataggtt ccaaagaggg cgataaattc cgcaagtttg
   110101 cccaggggct gacgctggat aatttagtcc atctcgctaa tcagcaactt acccggctgc
   110161 acgggcgcta tctgttacag cgcaaagcca gcgaggcgct ggaagtcgag gttgttgata
   110221 cctggcaggc agatgcggta cgcgataccc gtaccctttc cggcggcgaa agtttcctcg
   110281 ttagtctggc gctggcgctg gcgctttcgg atctggtcag ccataaaaca cgtattgact
   110341 cgctgttcct tgatgaaggt tttggcacgc tggatagcga aacgctggat accgcccttg
   110401 atgcgctgga tgccctgaac gccagtggca aaaccatcgg tgtgattagc cacgtagaag
   110461 cgatgaaaga gcgtattccg gtgcagatca aagtgaaaaa gatcaacggc ctgggctaca
   110521 gcaaactgga aagtacgttt gcagtgaaat aactattcag caggataatg aatacagagg
   110581 ggcgaattat ctcttggcct tgctggtcgt tatcctgcaa gctatcactt tattggctac
   110641 ggtgattggt agccgttctg gtggttgtga tggtggtatg aaaaaagtca ttttatcttt
   110701 ggctctgggc acgtttggtt tggggatggc cgaatttggc attatgggcg tgctcacgga
   110761 gctggcgcat aacgtaggaa tttcgattcc tgccgccggg catatgatct cgtattatgc
   110821 actgggggtg gtggtcggtg cgccaatcat cgcactcttt tccagccgct actcactcaa
   110881 acatatcttg ttgtttctgg tggcgttgtg cgtcattggc aacgccatgt tcacgctctc
   110941 ttcgtcttac ctgatgctcg ccattggtcg gctggtatcc ggctttccgc atggcgcatt
   111001 ttttggcgtc ggagcgatcg tgttatcaaa aattatcaaa cccggaaaag tcaccgccgc
   111061 cgtggcgggg atggtttccg ggatgacagt cgccaatttg ctgggcattc cgctgggaac
   111121 gtatttaagt caggaattta gctggcgtta caccttttta ttgatcgctg tttttaatat
   111181 tgcggtgatg gcatcggtct atttttgggt gccagatatt cgcgacgagg cgaaaggaaa
   111241 tctgcgcgaa caatttcact ttttgcgcag cccggccccg tggttaattt tcgccgccac
   111301 gatgtttggc aacgcaggtg tgtttgcctg gttcagctac gtaaagccat acatgatgtt
   111361 tatttccggt ttttcggaaa cggcgatgac ctttattatg atgttagttg ggctagggat
   111421 ggtgctggga aatatgctaa gtggcaggat ttcaggacgt tattcaccac tgcgcattgc
   111481 agcagtgact gactttataa ttgtactggc actgctgatg ctctttttct gcggcggcat
   111541 gaaaacaacg tcgcttattt ttgcttttat ttgttgcgcg ggattatttg ccctttcagc
   111601 accgctacaa atattgttac tacaaaacgc caaaggcgga gagttattag gtgccgcagg
   111661 tgggcaaata gcgtttaacc tcggtagcgc cgtcggcgca tattgcggag gtatgatgct
   111721 gacgctgggg ctggcatata attacgtggc gctgcctgcc gccctgcttt cgtttgctgc
   111781 gatgtcgtcg ttgctgctgt atggtcgcta taagcgccag caagcggcgg atactccggt
   111841 gctggcgaaa ccactggggt aggttatagt ctcggtgctc attacttatt gccggatgcg
   111901 gcgtgaacgc cttatccgcc ctacgcggtt ctggcacatt ttgcaggcct gataagacgc
   111961 ggcaagcgtc gcatcaggca tcggagcact tattgccgga tgcggcgtga acgccttatc
   112021 cggcctacgg ttctggcacc ttttgtaggc ctgataagac gcggcaagcg tcgcatcagg
   112081 catgatgcgc caattgccta cgttttttac tcttgtggcc ataaccacgc agcgccgcgt
   112141 acgccgctgg aatcaccgtg cttcgcctta cgcaccggcg tttcacattc gccgccgaag
   112201 acaaattgtt taatcaactg cccaaccgtt tgatataaac ggtctacatt gctcatcccg
   112261 ccccccagga caatcacatc cggatcgaga atattcacga catgtgccag cgattttgcc
   112321 agccgcagct cgtagcgacg caatgccagt tccgctaccg gatcgctttc ttcaaccagg
   112381 cggataattt cactgccttt cagcgcatgt ccgctcaaac gacgataatc catcgcgaat
   112441 cccgtgcccg aaataaaggt ttcaatacaa ccttgtttac cgcaataaca agggacttcc
   112501 tcgcgataac gcagttcgtc ttcgtccatc cacggtagcg gattgtgtcc ccactcacct
   112561 gccgtgccat tgccgccgat atgcgcccgc ccattgaatg ccacgcccgc gccgcatccc
   112621 gtgccgataa tcacggcaaa taccgtctgc gctcccgctg ccgcgccatc tactgcttct
   112681 gaaaccgcca gacagttagc gtcatttgcc agccgcactt cccgctgcaa cctcgcgctt
   112741 aagtctttat cgaatggctg accgttgagc caggttgaat tggcattctt caccacaccg
   112801 gtgtaaggcg aaattgagcc aggaatgccc atacctaccg ttccgcgctg ccccgtcgcc
   112861 tgctccgcca tatcaaccaa cgtggcgatc gtttcaatag tctgccggta atcatcacgc
   112921 ggcgtgggca gacgatggcg gtacaactgc tcccctgcat cgcccagtgc aatcacttca
   112981 gttttggtgc cgcctaaatc gatacctata cgcacggtac tctccttatt tttttcaata
   113041 tcaatagcgt agagacggac aaccggattg gcaatgcaag gccgccgaca attcgttatc
   113101 atgcccgcta aatttaacga caaggccgtg gaaattatca tgctgtggtt caaaaattta
   113161 atggtttacc gtcttagccg cgagatttcg ctgcgtgcag aagagatgga aaaacagcta
   113221 gcctcgatgg catttacccc atgcggcagc caggacatgg cgaagatggg ctgggttcct
   113281 ccgatgggat cgcacagcga tgcgttaacg cacgttgcca atggtcaaat tgttatctgc
   113341 gcgcgcaaag aagaaaaaat cctcccgtct ccggtgatta aacaggcgct ggaagcgaaa
   113401 atcgccaaac tggaagcgga acaggcgcgt aagctgaaga aaaccgaaaa agattcgctg
   113461 aaagacgaag tgctgcactc tctgctgccg cgtgctttca gccgttttag ccagacaatg
   113521 atgtggatcg acacggttaa cggtttgatt atggtggact gcgccagtgc caaaaaagcg
   113581 gaagatacgc tggcattact gcgtaaaagc ctggggtcgt taccggttgt accattgagc
   113641 atggaaaacc cgattgaact gacgctgacc gaatgggttc gctccggtag tgcggcacag
   113701 ggcttccagc tgcttgatga agccgagctg aaatcgttgc tggaagatgg cggcgtgatc
   113761 cgcgcgaaga aacaagatct gaccagcgaa gagatcacca atcacattga agccggaaaa
   113821 gtggtgacta aactggcgct cgactggcag cagcgcattc agtttgtgat gtgcgacgat
   113881 ggttcgctca agcgtctgaa gttctgcgac gagctgcgcg atcaaaacga agatatcgac
   113941 cgtgaagatt tcgcccagcg ttttgatgcc gatttcatcc tgatgactgg tgaactggca
   114001 gcgttaattc aaaacctgat tgaaggatta ggtggcgaag cacaacgtta attgctgatt
   114061 ttcctttaat gccggatgcg acgcctgccg cgtcttatcc ggcgtacgaa gccacaccag
   114121 gcatataatt attcgctacg gcgagcaata atttttagcg cagcaatatt atgcgtttta
   114181 cgctgtaact tgctccatgg acgttgtgtc attgtttttc ctcaagccgg tgacgcgctt
   114241 cactgcgaat tttccgcgtt gccccggttt tcactaaatc acgtaacagc gaaagatcgg
   114301 gttgttcgac aaataagagt aatgatggat cctcttttaa ccacgccgtt ttcacatcgg
   114361 cagccagctg tggattatta atagccagcg accgatcctg aggctcagtc aatgtcgtta
   114421 acaacaacgc cggggtatgt gcgttgcgca atgccgtttg gcgtaaatga tcattgcgac
   114481 tttgcagcaa tgcacgccac cattcatcat ctgatttatc ttttatcgta gccagttccg
   114541 caacaatatc tggagatctt cactgatatt tatatcaacc ttgataaatt atgaatatat
   114601 cggaaattga aaaaatcgca gcaaaggaaa tattattatg ggctaaagaa aggatatttc
   114661 agaaaaatgc cctcccgttc aaggggaagg cgaggaatta cagatagcgg cacagataag
   114721 aggtgggttc ggcaacttgc agatgaaact cactgtgacc gggaacatta aacaccgaac
   114781 cggcttcata cacctgccag tcggtcgcgt caggcagtaa cacattcagc gcgccactga
   114841 ttaccgtcat ctcttccggc tcagcggtgc tgaaggtgta ttcgccttca accataacac
   114901 ccacgctggc gcgaccagtg ctgctgctgg aaaagccgat tgatttcact ttgccggaaa
   114961 agtactcatt actttgaagc ataaactggc cctgtttggt agttgaacat ctacttcact
   115021 ataggggcca gaggcgctgg ctgtcacgca aaattacacc agtaattccg cagccagccg
   115081 tgcaatcaat acgttagaca gcaagacagg aacatcgagc tgtttttgca gtaaatcgcg
   115141 atgacgttgg tgaaatccta aacaatccag catgatgaca tcagcccctt ttgccagtaa
   115201 ttctttcccg gcatcaatga ttttttgttc tgaatcatga atggggttac ccaatgaaaa
   115261 taccggcgat ttctgcaaaa tttgccattt ttgcgcctga acgggcagca tctcctcaac
   115321 cggaacgata acccccacct gatgatcttc aacaatagag gaaaccagtg gaggcaatat
   115381 tcgcgacggc tcaagaaaga tcgtattacg cgcagtcata ctactaatgt ttgctgtact
   115441 cattaataaa atgacgtcat aaccctgatt atcgagcact tcaaccacac cttgcaggtc
   115501 acgctccact ttgcgacgcg aaacatgggc cagctggttg tcatttaata atgtgagaat
   115561 ggtgtcttcg cctgcttctg gcgcgtactc cgccatcact tcttcacgac ttaacttccc
   115621 cagcaggcta tgatgggaaa tattatcttc gtcaatgtat tccgtcagga gcggcaaaac
   115681 ttcctgcata ggtacaatgc cgatggtcag gatcgccaac gacgcactca ttgttcatcc
   115741 accttacttt tctttcgtcg ttaattaccg ggcaagtgtg aagcaccact gctgacactt
   115801 acttgtgcta caaatgacaa aaagcgtagc agcagacgtg cacggcataa tgtaaagatt
   115861 ccaaatgatt ccagtaatgg attgttattg tttaatattc taattattag aaaaacatga
   115921 attatgaaaa atgtgacgca gatcccttgt agtggcactc agaatccctt ccgagcagtc
   115981 tgatgcggtc actctttgtc agggtcctca tagcgttttt tcgcatccat cgcttcctga
   116041 gcggtcggat gttcactgat caacgagtct ggtttaggat gatcggctct gagttggtac
   116101 caggttaccg tctgtcctgg ctttcctttt tcaatcgtca ctatatatgc ttcacgagga
   116161 taaggcggtt tcgttggcat cgttcttcct tatttcacgg gatgaacgtt aagtataggc
   116221 gctcgaaaat caacaattga tcgtctgtgc cagggcgctg cgaatttcag aaatcacctg
   116281 gctgggttcg tttgttgcgt cgatgataat atgcgcaact tcgcgatata gcgcatcgcg
   116341 ttcttccagc acttcctgaa cttcttcgct cagcggtttt cccgttaagg ttggccgtaa
   116401 atcttcttcc ggtgcagctt gcagtcggtt aaccaggact gatactggcg cacacaaata
   116461 aaccacgatc ccgttatttt gcatgaagtg acgattaaat tccgtcagaa taatgccgcc
   116521 gcctgtagcg ataacggtgg atggcgcagt taccgcttcc agcgccgccg tttctctggc
   116581 gcgaaatccc gcccactctt ccctttcgac gatctccgcg accgtcatat tgagctgtga
   116641 ttgcaaccac tgatcggtat cgacaaaccg acggttaagc gaatcggcaa gggccattcc
   116701 gaccgttgtt ttaccacagc cccgaggccc gatcagaaaa agaggttgtg tcatcgtggg
   116761 ttttccccaa taggtcgcaa tgcggcgaaa gccggtgtca tgagaatagc gatcatacca
   116821 tcaaactagt acaatttcga ttgtaaagaa aaaattccac ttaaagtgaa aatctcaata
   116881 caccccttac tataccaata aatattcaag aatgaagtgt aaataataaa ttacatttag
   116941 ccacgactac gttgcacttc cagccaccac ttctccagct ccgcggcaaa ggcctggcgg
   117001 tcacgttgtg aaaggctatc tggtccgccg gtctggatcc cactggcacg taaggtatcc
   117061 ataaaatcgc gcatcgtcag gcgctcacga atggtcgctg gcgtgtaacg ttcgccgcgc
   117121 ggattaagcg ccgcagcgcc tttctcgatg gcttcagcag ccaaaggtat atctgcggtg
   117181 atcaccaaat cgcccgcttc acactgccgg acaatttcgt tatcggcaac gtcgaaacct
   117241 gccgcgacgc gcagcgtacg aataaatcgc gatggcggca cgcgtaaact ctggtttgct
   117301 accagtacca gcggcatctg catacgttcc gccgcgcgat acaaaatctc tttaattaca
   117361 ttgggacacg cgtcggcatc cacccaaatt gtcataaagt catcctttgt tgggtaatcc
   117421 tctattgtgt cgcgcttttg ccttccggca tagttctgtt tatgcttctg ccagcgatta
   117481 tcaaaacaat gaatttcacg gcaggagtga ggcaatggaa aagaaaatcg gttttattgg
   117541 ctgcggcaat atgggaaaag ccattctcgg cggtctgatt gccagcggtc aggtgcttcc
   117601 agggcaaatc tgggtataca ccccctcccc ggataaagtc gccgccctgc atgaccagtt
   117661 cggcatcaac gccgcagaat cggcgcaaga agtggcgcaa atcgccgaca tcatttttgc
   117721 tgccgttaaa cctggcatca tgattaaagt gcttagcgaa atcacctcca gcctgaataa
   117781 agactctctg gtcgtttcta ttgctgcagg tgtcacgctc gaccagcttg cccgcgcgct
   117841 gggccatgac cggaaaatta tccgcgccat gccgaacact cccgcactgg ttaatgccgg
   117901 gatgacctcc gtaacgccaa acgcgctggt aaccccagaa gataccgctg atgtgctgaa
   117961 tattttccgc tgctttggcg aagcggaagt aattgctgag ccgatgatcc acccggtggt
   118021 cggtgtgagc ggttcttcgc cagcctacgt atttatgttt atcgaagcga tggccgacgc
   118081 cgccgtgctg ggcgggatgc cacgcgccca ggcgtataaa tttgccgctc aggcggtaat
   118141 gggttccgca aaaatggtgc tggaaacggg agaacatccg ggggcactga aagatatggt
   118201 ctgctcaccg ggaggcacca ccattgaagc ggtacgcgta ctggaagaga aaggcttccg
   118261 tgctgcagtg atcgaagcga tgacgaagtg tatggaaaaa tcagaaaaac tcagcaaatc
   118321 ctgatgactt tcgccggacg tcaggccgcc acttcggtgc ggttacgtcc ggctttcttt
   118381 gctttgtaaa gcgccaaatc tgccgatttc aaccactcac gatagtgact catttgtggg
   118441 ttcagcggcg caacccccac actaatccgt aaagttacct gtggcgtatt cggcaaacgt
   118501 aatgtattta gcccttcatg cacccgtaac atggcggtaa tggcgctctc agctggcgta
   118561 ccggacatga ttactgcaaa ctcatcgccg ccaaaccgac caatcacatc gctaccgcgc
   118621 agggtaattt gtaactgtcg ggtaagcgcc acaatcgctt catcgcccac atcatggccc
   118681 caggtatcgt tgatgctctt gaaatggtcg atatcgataa tcagtaacgt tgcatcgcga
   118741 ttatgccgcc gacagttatc aaattcattg cgtaacatag tttcccaatg acgtcggtta
   118801 tacacgcccg tcatgccgtc gcgggtactc atgacctgca acctgcgttt atgttccgcc
   118861 agtttggttg ccgtctggta gctgacccag ccaaacagca gaggataaat gacaataatg
   118921 ggaagggaga gccaccattc cagcggcgca ctattgaacg acacggtaat gcccgtcagc
   118981 tcgagggtga caaggcagga aaccaccatc aacaccagac ccgcgacaaa cagacggggg
   119041 ccgcctgccc ccatcaaatt cagacacata atcatcaaca tcgcggtgga aggcagcacg
   119101 tttacgccca ttacgcctac ccacattccc gctaatactg catcggtttt taagttgtaa
   119161 atttcccggc taagcggatc gacggccctg ctcgctatct gccaggctaa atgcggccag
   119221 acgaacgccc agccgaccaa caccagccac caccagcccg gcggcgggtg tgaaaccagc
   119281 gttgaagcaa tcggtaagaa catgccagcc aggccaaccg cacggggtag tctgacgcga
   119341 cgggcgaagc gcagcccgga ccgctgatgt tcgttttgag gagttaaagg aggttcctcc
   119401 ccgtgcgccg ccgctttttt gaaaaagttt tcatcattca ttatttttgg gaacattcag
   119461 aaacaatttt cccaaattat agagacggag ctaaaggcag aagtatgata tttcgggtga
   119521 gccattttcg tagctcaccc gttagcacta tcaggtatca ggcggctttc ttgaggcagg
   119581 cactcataaa cttattacga tcatcacctt tcagagattg ttgtgttgct tgattattgc
   119641 attcgcgcat cttttgctgc tgtggcgtca aacttttttc gccaggcgca gacttgctgt
   119701 tcttcaggca atcactcatg taggtcttac gagcatcccc tttcaacgcc tgcgccgtcg
   119761 cctgctgatt acaggaggtc atacgctgtt gttgtggggt taaagttctc tcggcagcgc
   119821 cgacggtggt taaaaaaacc agaccgaaaa gcaaggtaac cagtaatgtt attttcatag
   119881 caccatccct cttcatgttt taaccatgag cgtatgcgcc cgtgatctgc cattaagtct
   119941 ggttgctaac agcaaaaaaa ccacccggca gcgaaaattc actgccgggc gcggttttat
   120001 ttcagcccca gagcggcttt catggtgtag aagagatcgg tctggtcggt cagtccaaca
   120061 acattggcgg catgcgggcc atacgccgca atacgcaact gactgccggt atgttcttgt
   120121 gaatcctctt cggagttccc gtaactcatc accatcactg cgccatcttt ggtatttagc
   120181 gcctgggtga ggcccggagc tttggtatcc ggcgcaacaa tctggctggc gtgggcgtga
   120241 tcagcggtga ctatgaccag cgtgttaccc tcctttttag cgaattccag cgcccgttgt
   120301 acggcttcat cgagatcgac cgtctcgcca atttgcccac aaggattcgc agcatgatcc
   120361 tgtttatcga ttgacgcacc ttcaacttgc aggaaaaagc ctttctcatt tttactcaac
   120421 aattcaatgg ctttgtcggt catctgcgcc agggttggta cactgtcatt acgttgcgga
   120481 tttggcgtac aggtgactgc gggcttatcg atattgccat ggtacgttgc tttcggtcct
   120541 agccagcgca ctggcatatt gccgtcagca aacaggccaa gcaggggttt ttgctgattc
   120601 gcttccgtca ccgaattcag tgaggcagca tcgctcacca actgataacc acgcgcctgt
   120661 gcctgttcac gcagcgtttt tccctgccat tcaccagcgg ttgccgtttc agcaaaggtt
   120721 tttgcgccgc cgccaagcgt aacgtcggca cgagcgttaa gcagctgttc ggtaatcgat
   120781 ccttttccgc ctttttccag agcgttaccc ggacattttt cactggtcgc gctcggaccg
   120841 tagcatttgc gcgaggtcac atgtgccacc agcgcagcgg gcgtggcatc ctgcaactct
   120901 gcggtagaaa cgttaccggt cgccagacct gcggcttttg ccatttccag aatcgttggg
   120961 tgatcttttt cgtgaatatc gacgcccagc gcgccgttat aggttttgac accggttgac
   121021 caggcggttg ctgatgcagc cgagtcggtg acgtagtccg gtttgccggt ttttttattc
   121081 agcgcatagt gagtgtattg cccggtaagc ggtaaggcat ctataccttt aaaaaagccg
   121141 cccgcacctt cggcataatt acgtgcggca gtaatttccg agtcccccat cccatcgcca
   121201 atcagcaaaa taatattttt tgcaggttta tcgctaagag aatcacgcag agcggcagtc
   121261 tgatcacccg ttaaacggcg agcaccgccg ggtgcagtaa tatcgccctg agcagcccgg
   121321 ttttccagaa caggcatttc tggtgtccgg gcttttgtca caggggtaaa cagtaacggt
   121381 aagagtgcca gtgcaatagt gctttgtttc actttatttt ctccatgtac aaatacatta
   121441 aaaaataaaa acaaagcgac tataagtctc ggccgtgaca actttatgac agctgttgaa
   121501 aagattaact ttttactgac gaggatgctt caataacttc tttacgtaat cgcgcagcag
   121561 ctccgtatcg tcgtcaggaa tgctggcatc gggctttacc tcgtacagcg ccccctctac
   121621 ctgatcaatc aaccgctgtt ggtcattttg cgccatattg cgaagcattg cagtgacgat
   121681 aatctccaaa gcttctacct gcgcacacag ttctttcgac tcttcttctt tttgggcaag
   121741 cttaaataac aactcagcaa tgagattttt catgtctgta tttccttatc caaagtatgg
   121801 agaagttaac attatgtttc acaacttcat agtgtctgga agtattattt ttatgacaaa
   121861 ggaaatactt tgcgcaaata ttttttgttt gattaccagc gaaacgtttc tcttatttaa
   121921 ataattaccc acacaaaata taggctttta attatcaacc tttattataa ataaaagtta
   121981 tgaaatatat tctcttcgtt aacttataat taagagaaaa aaactcaccg catggccatt
   122041 taagccagga ataaattagc ttcccgttca tcatttttgt gatcttgcgc acatctttga
   122101 gataacgcac tttcttcacc agtacgttgc acgctttgtc agcagaagat tgcaacaatc
   122161 tttcagaagg ccgcgaatcc cccgttttgt cgtggtaatg tatgcacttt gtgttagacg
   122221 ggataggttt ttaagatgga aaaactgcgg gtaggaatcg tttttggtgg taaatcagcg
   122281 gaacatgaag tgtctctgca atcggcaaaa aacattgtcg atgccattga taaaagtcgc
   122341 ttcgacgttg tgctgctggg cattgataaa caagggcaat ggcacgtcag cgatgccagc
   122401 aattatctgc taaatgcaga cgatcctgcc catattgcgt tgcgcccttc ggcgaccagc
   122461 cttgcgcagg tgccaggtaa acatgagcat cagcttatcg acgcgcaaaa cggtcagccg
   122521 ttgccgacgg tggatgtcat tttcccgatt gtccacggta cgctgggcga agatggttcc
   122581 ttgcagggaa tgctgcgggt cgccaattta ccgtttgtag gttctgatgt tctggcttca
   122641 gcagcctgta tggacaaaga tgtcaccaaa cgtctgctac gcgatgccgg gctgaacatt
   122701 gcgccattta ttaccctgac gcgcgccaat cgtcacaaca ttagttttgc cgaagtggag
   122761 tctaaactgg ggttaccact gtttgtaaaa ccggctaatc agggctcttc tgttggtgtc
   122821 agcaaagtaa ccagtgaaga acagtacgca attgccgtcg atctggcgtt cgagttcgat
   122881 cataaagtga tcgttgagca agggatcaaa ggtcgtgaga tcgaatgcgc agttctgggc
   122941 aacgacaatc cgcaagccag cacctgtgga gagatcgtac tcaccagcga tttctatgcc
   123001 tacgacacca agtacattga cgaagatggc gcgaaagtgg tagttccggc agccattgcg
   123061 ccagaaatca acgataagat ccgggcgatt gccgttcagg cttatcaaac gttgggatgc
   123121 gcaggcatgg cgcgtgtaga cgtgttttta accccagaga acgaagtggt gatcaacgag
   123181 atcaacaccc tgcctggctt cactaatatc agtatgtatc cgaagctgtg gcaagccagc
   123241 ggtctgggtt acaccgatct gatcacacgt ttgattgaac tggcgctgga gcgtcacgct
   123301 gcggataacg cattgaaaac cacaatgtaa tattttaacg cccgataata ttcttattgg
   123361 gcgttttcag tttcttcatc gcgacgacga ataatcaacc ccgccagcca gaaactaatc
   123421 acccacgtca ccagaccgac ggcataggtc tgccaacctt ttgcttcaaa tcccagtaac
   123481 cccaccacgc cattaagaat gaatataagg ccaatggcga acgcatagta gtgccagtca
   123541 cggcggattt ttacaggcag attcatggca gctccgttaa cgaaaaacaa catccttgca
   123601 tattctgcaa caaccgtctg tggtgtagac aacattttcg taattgttaa taaatttaac
   123661 ttaaggttgc cattttgtga ctcacaacga agattcacgc ttcgggaata ttcccaacat
   123721 caatttacca tgattctgat attgacaatc taaatgacct gtcagacttg ccataagccg
   123781 ctggtatcac accagaagag aagcagatga cttccggagg tttttatggc tgatttcacc
   123841 ctgtcaaaat cgctgtttag cggaaaatat cgcaatgcct cttcaacgcc tggcaacatt
   123901 gcctatgcgt tgtttgtgct gttttgcttt tgggctgggg cgcaattgct gaacctgtta
   123961 gtgcatgcgc ccggcgtcta tgagcgttta atgcaggtcc aggaaacagg tcgcccacgg
   124021 gtggaaattg gtttaggtgt cggcaccatt ttcgggctga tcccgttttt agtaggctgc
   124081 ctcatttttg cagtggtggc gctatggctg cactggcgac atcgccgcca gtaagtttta
   124141 cattgtcaga tgcggcctga aacgccttat ctggcctgac attcctgttt gatcactgtt
   124201 tcatacaacg cgcccgccgt tcgtctacgc gcttcgcaaa ccaggccgta gtcaggttgc
   124261 gggtgatttt cgggctttcc agttgaatgc caggcaacat ttcgcggggg agtgatttac
   124321 ccgttttcgt ttcggcaagt tgataaactt tcttgtacag cgccgtctcc tcaaaagaga
   124381 agctgtcacc tttctctaac tgacggcgaa tttcgctgtc gctcatcccc agttttgcag
   124441 ccagtttgcg cgttgccagt tcggttttcc cgggttcttt actgtcgtaa cgaattaaat
   124501 caccgtccag tgccagcttc acgccgctgg ccttactgac cgcgttctga aacgcggcat
   124561 tacggctggc gtaccagcca gcgttaaaat cagcaaaacg gtatatcggt gcgctataac
   124621 tggcgggata attcagtaaa tggtaagtac caaaccacaa cccgccgcgg cgactgaaga
   124681 cttcctgacg gactgtaccg tccattttcc acggataccc tttggtatgc tgttcggcaa
   124741 aagcaatgct gacctgcatc ggcccaccgg tgcgcaccgg attgagcgaa ccaaacagcg
   124801 tctgccccat tggcaccatg ttgatcagat cgtcaaaaat cgcgctcaat tgcttttctg
   124861 tacgcaccga atctaaccgt tcgctataac ttttgccgtt tggcgatttg atttttagcg
   124921 cggtatgaac cagaaaagca ggaatgtgca tccgttcagc acgacggtca atctcttgcc
   124981 aggcgatctt gcttaagccc ggaacggccg gatctgcctg ataatttgac tcctgctgcg
   125041 ccaccgccag caccgagcag acgttttcca gcgtcggtgc cagcccctga ctttcaaagg
   125101 tggtggcgag atctttcgcc caggcatcgc ggtctttcac gctcgcaggc atcttctgcc
   125161 gcacgacgct cgctacatct atcgcttttt cgcccttttt caacggttgc ggagcctgac
   125221 tactacaccc cgctaaaacc agaaccgcca acaatgacag cgaagataga ggattgacgc
   125281 gcgacattac ttctcctttt tagctcaagg tatgggttac ttcctgaatt ttgtcaccat
   125341 ccagctcatg ttcaaagctg cgcagacgtt tgtagataga catcaactca accagtgtgg
   125401 tccatgagtt aatcaggtac tggaaagcac cgcgaacctg accaaaaacg ttggtaatct
   125461 gcgtcatcag gccgagcgta atcgtaccgg caacaattga cggaaacagc aagaacaaac
   125521 cgaaaacgtt atcgacctgc aaatagagaa tgcgggcgat gttgaaatac atatagtgaa
   125581 aatagaggcg gaaatagttt ttccgtacgg cgctaaacag ctcgcgtacc gtaggcggcg
   125641 tcgcgcgcgt ggcatcgtct tcaccataaa ccagctcttt acggtaggca gcctctacac
   125701 gctggttttt aaactccagc cccggcagtt tgatccctac cactgccagc aatccggtcc
   125761 ccatcagcga ccagacgatt gcggcaatca ccagaccata cggaatgtgc ccgataatcg
   125821 gcagctccgg cacatgcgcg gagagcgtta ccagcaccgg caggaaggcg atcaacgtca
   125881 tgatggcgtt gataaaactg acgcccatat tctccagcgt tgaagcaaaa cgcatggtgt
   125941 cttcctgcac acgctgtgcg gccccttcga tatgacgcag ttgttgccag ttcgccatgt
   126001 aatattcgtt catcgctgta cgccagcgga acacgtagtg actgacaaag aagttgttca
   126061 gcacactgat caccacagcg atcagcgcaa tccccagaaa gacgcccact tcgcggtaaa
   126121 attgttcgat ggtgacttta tgcggcgaac ttagcgcggt ttgaatcaga tcatagaacg
   126181 gcgcatacca ggcgttgacg gcgaccccga cttccaccaa aaaccaggtg acgaagatga
   126241 tcagtgcagt accgagtatt gaccagtatt gccaacgatg cgggctgtag ataaaccaga
   126301 acaatgcaaa aagtcctacg caaacaatgt agtaagcgta aaaaatcagg aaatccaacg
   126361 accagaaacg cgcggcgcta atcgggatct gcccggaagc gccggtgata cgcgccaccc
   126421 agtcaccccc accggcttgc cagaagataa cggcaatcaa tgcccaaacg aaggccgaga
   126481 gaaaaaacgt tcccggcttt gggaaaaaag acttaaacat atgcactcct gctaacttct
   126541 tatcgtttta acaactgctg tgtattaacc gcatgaccgc tacaaagcgt cagccaaatg
   126601 aaaccgccca ttgtgaccca tagcaaggcg cttagttcgc cagcctgacc ataagaattg
   126661 tttcgacgga tttcacaaac caaagattgt ttacataagc ggattaacac gcgcaggatc
   126721 acaaatgcag gcattggtga gcaggaaaaa gatcgtgttt acgcgccgtt acgtttttaa
   126781 cactattatt gcactaattc gccctttgca atctatcaat gagtagtata aatacgctca
   126841 gttaccttca ttcaatctat ggacaccacc gttgaaacgt agtctgcttt tttctgccgt
   126901 gctgtgtgcg gcgtcattga cctccgtcca tgcggcgcag ccgatcactg aaccggagtt
   126961 tgcctctgat attgtcgatc gttatgccga tcatattttt tacggcagcg gtgccacggg
   127021 gatggctctg gttgttatcg acggtaacca gcgcgtcttt cgcagttatg gcgaaacgcg
   127081 acctggtaat aacgttcgcc cgcagctgga ttcggtcgtg cgtattgctt ccctcaccaa
   127141 gctaatgacc agtgagatgc tggtgaaatt gctcgaccag gggaccgtga agttaaacga
   127201 tccgctaagt aaatatgctc cgccaggcgc acgcgtgcca acctacaatg ggacgcccat
   127261 tacgctggtc aatctggcaa cccataccag cgccctgccc cgtgaacagc ccggtggcgc
   127321 ggcacatcgt ccggtgtttg tctggccaac gcgcgagcaa cgctggaaat acctttctac
   127381 ggcgaagctg aaagccgcgc caggcagtca ggcggcgtac tctaaccttg cgttcgacct
   127441 gctggcagat gcactggcga atgcgtccgg caagccttat acccagttgt ttgaagagca
   127501 gattacccgt ccattgggga tgaaagacac cacctacacc ccctcaccgg atcagtgccg
   127561 ccgtttaatg gttgctgagc gcggtgccag tccgtgcaat aacacgctgg cggcaattgg
   127621 cagcggcggc gtctattcca cgcctggcga tatgatgcgc tggatgcagc agtatttgtc
   127681 atctgatttt tatcagcgca gtaaccaggc agatcgcatg cagacgttga tttatcagcg
   127741 cgcgcagttt acgaaagtga ttggcatgga tgtccccggc aaagcggatg cgcttggttt
   127801 aggttgggta tatatggccc cgaaagaggg tcgtccgggg attattcaga agacaggcgg
   127861 tggtggcggt ttcattacct atatggcgat gatcccgcag aagaatattg gcgcgtttgt
   127921 ggtggtcact cgttcgccgt tgacgcgctt taaaaatatg agcgatggca tcaatgacct
   127981 ggtgaccgag ctaagcggga ataaaccgtt ggttatcccc gcgtcctgat taatactctg
   128041 aaggcaaacg gttgatagcg accagtttgc ctttattcat ttcgatatag ccgcctttac
   128101 gcaaagcagc gagaacttct gcgacgacag aacgcgatat gcgtgtacgt tgatggatat
   128161 aattcatcac accaatacgt gatcgcaatt cttcattcca gtcaatcatt gataataatg
   128221 ttgcgcggat ttgttcgtag gaattatgcc caatgagctg cacgtcgcgt aattccagaa
   128281 ttctattttg ccaggctaac cagtaaaaag cgtctcgcca gagttgattt tgttcaataa
   128341 gcgtaatggt ttgtttggct ggtagatgat atcccgtaca atttccttct gatattaatt
   128401 tgtatggtat atcgtttttc attaaaccat cagccagccc cataatataa ggagcctggg
   128461 taataccgat aagtacgttt tcttctctac gcagagagat aactccctct aaaataacga
   128521 aagtatcttc gttattgaca tcactggaaa atataacttg cttttcatta ttaaactcga
   128581 agcgcgtacc gtatctggac aaacatttat cgagcttacc aaattcctga agaggtttaa
   128641 ctacagataa catttgcgcg tcctttgcag taatgcccgt caaatccttg acgggcatta
   128701 tttagattaa
//
LOCUS       DAPOAV010000002       118798 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.002, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000002 DAPOAV010000000
VERSION     DAPOAV010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 118798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 118798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..118798
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.002"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            33..617
                     /locus_tag="RN951_000124"
     CDS             33..617
                     /locus_tag="RN951_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDX2525192.1"
                     /translation="MNKVTKTAIAGLLALFAGNAAATDGEIVFDGEILKSACEINDSD
                     KKIEVALGHYNAEQFRNIGERSPKIPFTIPLVNCPMTGWEHDNGNVEASFRLWLETRD
                     NGTVPNFPNLAKVGSFAGIAATGVGIRIDDAESGNIMPLNAMGNDNTVYQIPAESNGI
                     VNVDLIAYYVSTVVPSEITPGEADAIVNVTLDYR"
     gene            697..1392
                     /locus_tag="RN951_000125"
     CDS             697..1392
                     /locus_tag="RN951_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDX2525193.1"
                     /translation="MSKRTFAVILTLLCSFCIGQALAGGIVLQRTRVIYDASRKEAAL
                     PVANKGAETPYLLQSWVDNIDGKSRAPFIITPPLFRLEAGDDSSLRIIKTADNLPENK
                     ESLFYINVRAIPAKKKSDDVNANELTLVFKTRIKMFYRPAHLKGRVNDAWKSLEFKRS
                     DHSLNIYNPTEYYVVFAGLAVDKTDLTSKIEYIAPGEHKQLPLPASGGKNVKWAAIND
                     YGGSSGTETRPLQ"
     gene            1422..3938
                     /locus_tag="RN951_000126"
     CDS             1422..3938
                     /locus_tag="RN951_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDX2525194.1"
                     /translation="MPQRHHQGHKRTPKQLALIIKRCLPMVLTGSGMLCTTANAEEYY
                     FDPIMLETTKSGMQTTDLSRFSKKYAQLPGTYQVDIWLNKKKVSQKKITFTANAEQLL
                     QPQFTVEQLRELGIKVDEIPALAEKDDDSVINSLEQIIPGTAAEFDFNHQQLNLSIPQ
                     IALYRDARGYVSPSRWDDGIPTLFTNYSFTGSDNRYRQGNRSQRQYLNMQNGANFGPW
                     RLRNYSTWTRNDQTSSWNTISSYLQRDIKALKSQLLLGESATSGSIFSSYTFTGVQLA
                     SDDNMLPNSQRGFAPTVRGIANSSAIVTIRQNGYVIYQSNVSAGAFEINDLYPSSNSG
                     DLEVTIEESDGTQRRFIQPYSSLPMMQRPGHLKYSATAGRYRADANSDSKEPEFAEAT
                     AIYGLNNTFTLYGGLLGSEDYYALGIGIGGTLGALGALSMDINRADTQFDNQHSFHGY
                     QWRTQYIKDIPETNTNIAVSYYRYTNDGYFSFNEANTRNWDYNSRQKSEIQFNISQTI
                     FDGVSLYASGSQQDYWGNNDKNRNISVGVSGQQWGVGYSLNYQYSRYTDQNNDRALSL
                     NLSIPLERWLPRSRVSYQMTSQKDRPTQHEMRLDGSLLDDGRLSYSLEQSLDDDNNHN
                     SSLNASYRSPYGTFSAGYSYGNDSSQYNYGVTGGVVIHPHGVTLSQYLGNAFALIDAN
                     GASGVRIQNYPGIATDPFGYAVVPYLTTYQENRLSVDTTQLPDNVDLEQTTQFVVPNR
                     GAMVAARFNANIGYRVLVTVSDRNGKPLPFGALASNDDTGQQSIVDEGGILYLSGISS
                     KSQSWTVRWGNQADQQCQFAFSTPDSEPTTSVLQGTAQCH"
     gene            3949..5040
                     /locus_tag="RN951_000127"
     CDS             3949..5040
                     /locus_tag="RN951_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX2525195.1"
                     /translation="MKRAPLITGLLLISTSCAYASSGGCGADSTSGATNYSSVVDDVT
                     VNQTDNVTGREFTSATLSSTNWQYACSCSAGKAVKLVYMVSPVLTTTGHQTGYYKLND
                     SLDIKTTLQANDIPGLTTDQVVSVNTRFTQIKNNTVYSAATQTGVCQGDTSRYGPVNI
                     GANTTFTLYVTKPFLGSMTIPKTDIAVIKGAWVDGMGSPSTGDFHDLVKLSIQGNLTA
                     PQSCKINQGDVIKVNFGFINGQKFTTRNAMPDGFTPVDFDITYDCGDTSKIKNSLQMR
                     IDGTTGVVDQYNLVARRRSSDNVPDVGIRIENLGGGVANIPFQNGILPVDPSGHGTVN
                     MRAWPVNLVGGELETGKFQGTATITVIVR"
     gene            complement(5083..5943)
                     /gene="rsmI"
                     /locus_tag="RN951_000128"
     CDS             complement(5083..5943)
                     /gene="rsmI"
                     /locus_tag="RN951_000128"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HDX2525196.1"
                     /translation="MKQHQSADNSQGQLYIVPTPIGNLADITQRALEVLQAVDLIAAE
                     DTRHTGLLLQHFGINARLFALHDHNEQQKAETLLAKLQEGQNIALVSDAGTPLINDPG
                     YHLVRTCREAGIRVVPLPGPCAAITALSAAGLPSDRFCYEGFLPAKSKGRRDALKAIE
                     AEPRTLIFYESTHRLLDSLEDIVAVLGESRYVVLARELTKTWETIHGAPVGELLAWVK
                     EDENRRKGEMVLIVEGHKAQEEDLPADALRTLALLQAELPLKKAAALAAEIHGVKKNA
                     LYKYALEQQG"
     gene            6008..8044
                     /gene="lpoA"
                     /locus_tag="RN951_000129"
     CDS             6008..8044
                     /gene="lpoA"
                     /locus_tag="RN951_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator LpoA"
                     /protein_id="HDX2525197.1"
                     /translation="MVPSTFSRLKAARCLPVVLAALIFAGCGTHTPDQSTAYMQGTAQ
                     ADSAFYLQQMQQSSDDTRINWQLLAIRALVKEGKTGQAVELFNQLPQELNDAQRREKT
                     LLAVEIKLAQKDFAGAQNLLAKITPADLEQNQQARYWQAKIDASQGRPSIDLLRALIA
                     QEPLLGAKEKQQNIDATWQALSSMTQEQANTLVINADENILQGWLDLQRVWFDNRNDP
                     DMMKAGIADWQKRYPNNPGAKMLPTQLVNVKAFKPASTNKIALLLPLNGQAAVFGRTI
                     QQGFEAAKNIGTQPVAAQVAAAPAADVAEQPQPQTVDGVASPAQASVSDLTGEQPAAQ
                     PVPVSAPATSTAAVSAPANPSAELKIYDTSSQPLSQILSQVQQDGASIVVGPLLKNNV
                     EELLKSNTPLNVLALNQPENIENRVNICYFALSPEDEARDAARHIRDQGKQAPLVLIP
                     RSSLGDRVANAFAQEWQKLGGGTVLQQKFGSTSELRAGVNGGSGIALTGSPITLRATT
                     DSGMTTNNPTLQTTPTDDQFTNNGGRVDAVYIVATPGEIAFIKPMIAMRNGSQSGATL
                     YASSRSAQGTAGPDFRLEMEGLQYSEIPMLAGGNLPLMQQALSAVNNDYSLARMYAMG
                     VDAWSLANHFSQMRQVQGFEINGNTGSLTANPDCVINRNLSWLQYQQGQVVPAS"
     gene            8002..8397
                     /locus_tag="RN951_000130"
     CDS             8002..8397
                     /locus_tag="RN951_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HDX2525198.1"
                     /translation="MATVPTRSGSPRQLTTKQTGDAWEVQARRWLEGKGLRFVAANVN
                     ERGGEIDLIMREGRTTVFVEVRYRRSALYGGAAASVTRSKQHKLLQTARLWLARHNGS
                     FDTVDCRFDVVAFTGNEVEWIKDAFNDHS"
     gene            8417..9007
                     /gene="diaA"
                     /locus_tag="RN951_000131"
     CDS             8417..9007
                     /gene="diaA"
                     /locus_tag="RN951_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA initiator-associating protein DiaA"
                     /protein_id="HDX2525199.1"
                     /translation="MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKI
                     LCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQ
                     VRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVE
                     IRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDD"
     gene            9017..9592
                     /gene="yraP"
                     /locus_tag="RN951_000132"
     CDS             9017..9592
                     /gene="yraP"
                     /locus_tag="RN951_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divisome-associated lipoprotein YraP"
                     /protein_id="HDX2525200.1"
                     /translation="MKALSPIAVLISALLLQGCVAAAVVGTAAVGTKAATDPRSVGTQ
                     VDDGTLEVRVNSALSKDEQIKKETRINVTAYQGKVLLVGQSPNAELSARAKQIAMGVD
                     GANEVYNEIRQGQPIGLGEASNDTWITTKVRSQLLTSDLVKSSNVKVTTENGEVFLMG
                     LVTEREAKAAADIASRVSGVKRVTTAFTFIK"
     gene            complement(9706..10746)
                     /locus_tag="RN951_000133"
     CDS             complement(9706..10746)
                     /locus_tag="RN951_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDX2525201.1"
                     /translation="MTGQSSSQAATPIQWWKPALFFLVVIAGLWYVKWEPYYGKAFTA
                     AETHSIGKSILAQADANPWQAALDYAMIYFLAVWKAAVLGVILGSLIQVLIPRDWLLR
                     TLGQSRFRGTLLGTLFSLPGMMCTCCAAPVAAGMRRQQVSMGGALAFWMGNPVLNPAT
                     LVFMGFVLGWGFAVIRLVAGLVMVLLIATLVQKWVRETPQTQAPVEIDIPEAQGGFFS
                     RWGRALWTLFWSTIPVYILAVLVLGAARVWLFPHADGAVDNSLMWVVAMAVAGCLFVI
                     PTAAEIPIVQTMMLAGMGTAPALALLMTLPAVSLPSLIMLRKAFPAKALWLTGAMVAV
                     SGVIVGGLALLF"
     gene            complement(10819..11454)
                     /locus_tag="RN951_000134"
     CDS             complement(10819..11454)
                     /locus_tag="RN951_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417621.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HDX2525202.1"
                     /translation="MSQVLITGATGLVGGHLLRMLINEPKVNAIAAPTRRPLGDMPGV
                     FNPHDPQLSDALAQVTDPIDIVFCCLGTTRREAGSKEAFIHADYTLVVDTALTGRRLG
                     AQHMLVVSAMGANAHSPFFYNRVKGEMEEALIAQNWPKLTIARPSMLLGDRSKQRMNE
                     TLFAPLCRLLPGNWKSIDARDVARVMLAESMWPEHEGVTILSSSELRKRAE"
     gene            11582..12100
                     /gene="yhbO"
                     /locus_tag="RN951_000135"
     CDS             11582..12100
                     /gene="yhbO"
                     /locus_tag="RN951_000135"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417622.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein/nucleic acid deglycase"
                     /protein_id="HDX2525203.1"
                     /translation="MSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVK
                     GKKGEASVTIDKSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFA
                     ICHGPQLLISADVIRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLP
                     AFNREALRLLGA"
     gene            complement(12080..12523)
                     /locus_tag="RN951_000136"
     CDS             complement(12080..12523)
                     /locus_tag="RN951_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbP family protein"
                     /protein_id="HDX2525204.1"
                     /translation="METLIAISRWLAKQHVVTWCVQQEGELWCANAFYLFDAQKVAFY
                     ILTEEKTRHAQMSGPQAAVAGTVNGQPKTVALIRGVQFKGEIRRLEGEESDLARKAYN
                     RRFPVARMLSAPVWEIRLDEIKFTDNTLGFGKKMIWLRDSGTEQA"
     gene            12574..12876
                     /gene="yhbQ"
                     /locus_tag="RN951_000137"
     CDS             12574..12876
                     /gene="yhbQ"
                     /locus_tag="RN951_000137"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708956.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage response exodeoxyribonuclease YhbQ"
                     /protein_id="HDX2525205.1"
                     /translation="MTPWFLYLIRTADNKLYTGITTDVERRYQQHQSGKGAKALRGKG
                     ELTLAFSAPVGDRSLALRAEYRVKQLTKRQKERLVAEGAGFAELLSSLQTPEIKSD"
     gene            complement(12863..13366)
                     /locus_tag="RN951_000138"
     CDS             complement(12863..13366)
                     /locus_tag="RN951_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDX2525206.1"
                     /translation="MLIRVEIPIDAPGIDALLRRSFESDAEAKLVHDLREDGFLTLGL
                     VATDDEGQVIGYVAFSPVDVQGEDLQWVGMAPLAVDEKYRGQGLARQLVYEGLDSLNE
                     FGYAAVVTLGDPALYSRFGFELAAHHDLRCRWPGTESAFQVHRLADDALNGVTGLVEY
                     HEHFNRF"
     gene            complement(13360..13884)
                     /locus_tag="RN951_000139"
     CDS             complement(13360..13884)
                     /locus_tag="RN951_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SCP2 domain-containing protein"
                     /protein_id="HDX2525207.1"
                     /translation="MLDKLRSRIVHLGPSLLSVPVKLTPFALKRQVLEQVLSWQFRQA
                     LDDGELEFLEGRWLSIHVRDIDLQWFTSVVNGKLVVSQNAQADVSFSADASDLLMIAA
                     RKQDPDTLFFQRRLVIEGDTELGLYVKNLMDAIELEQMPKALRMMLLQLADFVEAGMK
                     TAPETKQTSVGEPC"
     gene            14093..15088
                     /locus_tag="RN951_000140"
     CDS             14093..15088
                     /locus_tag="RN951_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017457364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDX2525208.1"
                     /translation="MELLCPAGNLPALKAAIENGADAVYIGLKDDTNARHFAGLNFTE
                     KKLQEAVSFVHQHRRKLHIAINTFAHPDGYARWQRAVDMAAQLGADALILADLAMLEY
                     AAERYPHIERHVSVQASATNEEAINFYHRHFDVARVVLPRVLSIHQVKQLARVTPVPL
                     EVFAFGSLCIMSEGRCYLSSYLTGESPNTVGACSPARFVRWQQTPQGLESRLNEVLID
                     RYQDGENAGYPTLCKGRYLVDGERYHALEEPTSLNTLELLPELMAANIASVKIEGRQR
                     SPAYVSQVAKVWRQAIDRCKADPQNFVPQSAWMETLGSMSEGTQTTLGAYHRKWQ"
     gene            15097..15975
                     /locus_tag="RN951_000141"
     CDS             15097..15975
                     /locus_tag="RN951_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417628.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDX2525209.1"
                     /translation="MKYSLGPVLWYWPKETLEEFYQQAATSSADVIYLGEAVCSKRRA
                     TKVGDWLEMAKSLAGSGKQIVLSTLALVQASSELGELKRYVENGEFLIEASDLGVVNM
                     CAERKLPFVAGHALNCYNAVTLKILLKQGMMRWCMPVELSRDWLVNLLNQCDELGIRN
                     QFEVEVLSYGHLPLAYSARCFTARSEDRPKDECETCCIKYPNGRNVLSQENQQVFVLN
                     GIQTMSGYVYNLGNELASMQGLVDVVRLSPQGTDTFAMLDAFRANENGAAPLPLTANS
                     DCNGYWRRLAGLELQA"
     gene            16056..17063
                     /locus_tag="RN951_000142"
     CDS             16056..17063
                     /locus_tag="RN951_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="luciferase-like monooxygenase"
                     /protein_id="HDX2525210.1"
                     /translation="MTDKTIAFSLLDLAPIPEGSSAREAFSHSLDLARLAEKRGYHRY
                     WLAEHHNMTGIASAATSVLIGYLAANTTTLHLGSGGVMLPNHSPLVIAEQFGTLNTLY
                     PGRIDLGLGRAPGSDQRTMMALRRHMSGDIDNFPRDVAELVDWFDARDPNPHVRPVPG
                     YGEKIPVWLLGSSLYSAQLAAQLGLPFAFASHFAPDMLFQALHLYRSNFKPSARLEKP
                     YAMVCINIIAADSNRDAEFLFTSMQQAFVKLRRGETGQLPPPIQNMDQFWSPSEQYGV
                     QQALSMSLVGDKAKVRHGLQSILRETDADEIMVNGQIFDHQARLHSFELAMDVKEELL
                     G"
     gene            complement(17181..18425)
                     /gene="mtr"
                     /locus_tag="RN951_000143"
     CDS             complement(17181..18425)
                     /gene="mtr"
                     /locus_tag="RN951_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan permease"
                     /protein_id="HDX2525211.1"
                     /translation="MATLTTTQTSPSLLGGVVIIGGTIIGAGMFSLPVVMSGAWFFWS
                     MAALIFTWFCMLHSGLMILEANLNYRIGSSFDTITKDLLGKGWNVVNGISIAFVLYIL
                     TYAYISASGSILHHTFAEMSLNVPARAAGFGFALLVAFVVWLSTKAVSRMTAIVLGAK
                     VITFFLTFGSLLGHVQPATLFNVAESNASYAPYLLMTLPFCLASFGYHGNVPSLMKYY
                     GKDPKTIVKCLVYGTLMALALYTIWLLATMGNIPRPEFIGIAEKGGNIDVLVQALSGV
                     LNSRSLDLLLVVFSNFAVASSFLGVTLGLFDYLADLFGFDDSAVGRLKTALLTFAPPV
                     VGGLLFPNGFLYAIGYAGLAATIWAAIVPALLARASRKRFGSPKFRVWGGKPMIALIL
                     VFGVGNALVHILSSFNLLPVYQ"
     gene            complement(18579..20468)
                     /gene="deaD"
                     /locus_tag="RN951_000144"
     CDS             complement(18579..20468)
                     /gene="deaD"
                     /locus_tag="RN951_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417631.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DeaD"
                     /protein_id="HDX2525212.1"
                     /translation="MAEFETTFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGR
                     DVLGMAQTGSGKTAAFSLPLLQNLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMR
                     GVNVVALYGGQRYDVQLRALRQGPQIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADE
                     MLRMGFIEDVETIMAQIPEGHQTALFSATMPEAIRRITRRFMKEPQEVRIQSSVTTRP
                     DISQSYWTVWGMRKNEALVRFLEAEDFDAAIIFVRTKNATLEVAEALERNGYNSAALN
                     GDMNQALREQTLERLKDGRLDILIATDVAARGLDVERISLVVNYDIPMDSESYVHRIG
                     RTGRAGRAGRALLFVENRERRLLRNIERTMKLTIPEVELPNAELLGKRRLEKFAAKVQ
                     QQLESSDLDQYRALLSKIQPTAEGEELDLETLAAALLKMAQGERTLIVPPDAPMRPKR
                     EFRDRDDRGPRDRNDRGPRGDREDRPRRERRDVGDMQLYRIEVGRDDGVEVRHIVGAI
                     ANEGDISSRYIGNIKLFASHSTIELPKGMPGEVLQHFTRTRILNKPMNMQLLGDAQPH
                     TGGERRGGGRGFGGERREGGRNFSGERREGGRGDGRRFSGERREGRAPRRDDSTGRRR
                     FGGDA"
     gene            complement(20461..20541)
                     /gene="yrbN"
                     /locus_tag="RN951_000145"
     CDS             complement(20461..20541)
                     /gene="yrbN"
                     /locus_tag="RN951_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YrbN"
                     /protein_id="HDX2525213.1"
                     /translation="MKIADQFHDELCRLAAINFEAHVLHG"
     gene            complement(20648..21532)
                     /gene="nlpI"
                     /locus_tag="RN951_000146"
     CDS             complement(20648..21532)
                     /gene="nlpI"
                     /locus_tag="RN951_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020802045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein NlpI"
                     /protein_id="HDX2525214.1"
                     /translation="MKPFLRWCFVATALTLAGCSNTSWRKSEVLAVPLQPTLQQEVIL
                     ARMEQILASRALTDDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYL
                     GIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDD
                     PNDPFRSLWLYLAEQKLDEKQAKEVLKQHFEKSDKEQWGWNIVEFYLGNISEQTLMER
                     LKADATDNTSLAEHLSETNFYLGKYYLSLGDLDSATALFKLAVANNVHNFVEHRYALL
                     ELSLLGQDQDDLAESDQQ"
     gene            complement(21641..23776)
                     /gene="pnp"
                     /locus_tag="RN951_000147"
     CDS             complement(21641..23776)
                     /gene="pnp"
                     /locus_tag="RN951_000147"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417633.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HDX2525215.1"
                     /translation="MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTV
                     VGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIRPL
                     FPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQ
                     YVLNPTQDELKESKLDLVVAGTEAAVLMVESEAQLLSEDQMLGAVVFGHEQQQVVIQN
                     INELVKEAGKPRWDWQPEPVNEALNARVAALAEARLSDAYRITDKQERYAQVDVIKSE
                     TIATLLAEDETLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVL
                     PRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGM
                     VGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLAL
                     MDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMD
                     IKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKINPDKIK
                     DVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKHAIRRIEEITAEIEVGRV
                     YTGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQ
                     GRIRLSIKEATEQSQPAAAPEAPAAEQGE"
     gene            complement(24023..24292)
                     /gene="rpsO"
                     /locus_tag="RN951_000148"
     CDS             complement(24023..24292)
                     /gene="rpsO"
                     /locus_tag="RN951_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HDX2525216.1"
                     /translation="MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFA
                     EHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR"
     gene            complement(24441..25385)
                     /gene="truB"
                     /locus_tag="RN951_000149"
     CDS             complement(24441..25385)
                     /gene="truB"
                     /locus_tag="RN951_000149"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HDX2525217.1"
                     /translation="MSRPRRRGRDINGVLLLDKPQGMSSNDALQKVKRIYNANRAGHT
                     GALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVEERPVT
                     FSAEQLAAALDTFRGDIEQIPSMYSALKYQGKKLYEYARQGIEVPREARPITVYELLF
                     IRHEGNELELEIHCSKGTYIRTIIDDLGEKLGCGAHVIYLRRLAVSKYPVERMVTLEH
                     LRELVEQAEQQDIPAAELLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTSGAP
                     LEGLVRVTEGENGKFIGMGEIDDEGRVAPRRLVVEYPA"
     gene            complement(25385..25786)
                     /gene="rbfA"
                     /locus_tag="RN951_000150"
     CDS             complement(25385..25786)
                     /gene="rbfA"
                     /locus_tag="RN951_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001712908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HDX2525218.1"
                     /translation="MAKEFGRPQRVAQEMQKEIALILQREIKDPRLGMMTTVSGVEMS
                     RDLAYAKVYVTFLNDKDEDAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNS
                     LVEGMRMSNLVTSVVKHDEERRVNPDDSKED"
     gene            complement(25950..28622)
                     /gene="infB"
                     /locus_tag="RN951_000151"
     CDS             complement(25950..28622)
                     /gene="infB"
                     /locus_tag="RN951_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HDX2525219.1"
                     /translation="MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQT
                     LIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERL
                     AAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSN
                     QQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDN
                     AEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADRE
                     EARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIK
                     AMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAP
                     VVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAA
                     FTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAVNKIDKPEADPD
                     RVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMAS
                     GAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSI
                     PVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMT
                     EGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASN
                     AILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLA
                     EVRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVR
                     NGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA"
     gene            complement(28647..30134)
                     /gene="nusA"
                     /locus_tag="RN951_000152"
     CDS             complement(28647..30134)
                     /gene="nusA"
                     /locus_tag="RN951_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005131833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HDX2525220.1"
                     /translation="MNKEILAVVEAVSNEKALPREKIFEALESALATATKKKYEQEID
                     VRVQIDRKSGDFDTFRRWLVVDEVTQPTKEITLEAARYEDESLNLGDYVEDQIESVTF
                     DRITTQTAKQVIVQKVREAERAMVVDQFREHEGEIITGVVKKVNRDNISLDLGNNAEA
                     VILREDMLPRENFRPGDRVRGVLYSVRPEARGAQLFVTRSKPEMLIELFRIEVPEIGE
                     EVIEIKAAARDPGSRAKIAVKTNDKRIDPVGACVGMRGARVQAVSTELGGERIDIVLW
                     DDNPAQFVINAMAPADVASIVVDEDKHTMDIAVEAGNLAQAIGRNGQNVRLASQLSGW
                     ELNVMTVDDLQAKHQAEAHAAIDTFTKYLDIDEDFATVLVEEGFSTLEELAYVPMKEL
                     LEIEGLDEPTVEALRERAKNALATIAQAQEESLGDNKPADDLLNLEGVDRDLAFKLAA
                     RGVCTLEDLAEQGIDDLADIEGLTDEKAGALIMVARNICWFGDEA"
     gene            complement(30162..30614)
                     /gene="rimP"
                     /locus_tag="RN951_000153"
     CDS             complement(30162..30614)
                     /gene="rimP"
                     /locus_tag="RN951_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HDX2525221.1"
                     /translation="MSTLEQKLTEMITAPVEVLGFELVGIEFIRGRTSTLRIYIDSED
                     GINVDDCADVSHQVSAVLDVEDPITVAYNLEVSSPGLDRPLFTAEHYARFVGEEVTLV
                     LRMAVQNRRKWQGVIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF"
     gene            complement(30821..30897)
                     /locus_tag="RN951_000154"
     tRNA            complement(30821..30897)
                     /locus_tag="RN951_000154"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(30861..30863),aa:Met,seq:cat)
     gene            31245..32588
                     /gene="argG"
                     /locus_tag="RN951_000155"
     CDS             31245..32588
                     /gene="argG"
                     /locus_tag="RN951_000155"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HDX2525222.1"
                     /translation="MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTAN
                     LGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNT
                     TPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDT
                     DFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVN
                     PIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMS
                     DQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQG
                     RWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKG
                     DSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQVENLENKGQ"
     gene            complement(32596..34221)
                     /locus_tag="RN951_000156"
     CDS             complement(32596..34221)
                     /locus_tag="RN951_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417641.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HDX2525223.1"
                     /translation="MTVFNKFARTFKSHWLLYLCVIVFGITNLVASSGAHMVQRLLFF
                     VLTILVVKRISSLPLRLLVAAPFVLLTAADMSISLYSWCTFGTTFNDGFAISVLQSDP
                     DEVVKMLGMYIPYLCAFAFLSLLFLAVIIKYDVSLPTKKVTGILLLIVISGSLFSACQ
                     FAYKDAKNKKAFSPYILASRFATYTPFFNLNYFALAAKEHQRLLSIANTVPYFQLSVR
                     DTGIDTYVLIVGESVRVDNMSLYGYTRSTTPQVEAQRKQIKLFNQAISGAPYTALSVP
                     LSLTADSVLSHDIHNYPDNIINMANQAGFQTFWLSSQSAFRQNGTAVTSIAMRAMETV
                     YVRGFDELLLPHLSQALQQNTQQKKLIVLHLNGSHEPACSAYPQSSAVFQPQDDQDAC
                     YDNSIHYTDSLLGQVFELLKDRRASVMYFADHGLERDPTKKNVYFHGGREASQQAYHV
                     PMFIWYSPVLGDGVDRTTENNIFSTAYNNYLINAWMGVTKPEQPQTLEEVIAHYKGDS
                     RVVDANHDVFDYVMLRKEFTEDKQGNPTPEGQG"
     gene            complement(34680..34766)
                     /locus_tag="RN951_000157"
     tRNA            complement(34680..34766)
                     /locus_tag="RN951_000157"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(34730..34732),aa:Leu,seq:gag)
     gene            complement(34781..35113)
                     /gene="secG"
                     /locus_tag="RN951_000158"
     CDS             complement(34781..35113)
                     /gene="secG"
                     /locus_tag="RN951_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HDX2525224.1"
                     /translation="MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFG
                     SSGSGNFMTRMTALLATLFFIISLVLGNINSNKTNKGSEWENLSAPAKTEQTQPAAPA
                     KPTSDIPN"
     gene            complement(35341..36678)
                     /gene="glmM"
                     /locus_tag="RN951_000159"
     CDS             complement(35341..36678)
                     /gene="glmM"
                     /locus_tag="RN951_000159"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HDX2525225.1"
                     /translation="MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRK
                     IIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISAS
                     HNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIE
                     FCKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVG
                     ATDVRALQARVLAEKADLGIAFDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQL
                     RGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGWRIGAENSGHVILLD
                     KTTTGDGIVAGLQVLAAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVK
                     AVTAEVEAALGNRGRVLLRKSGTEPLIRVMVEGEDEAQVTEFAHRIADAVKAV"
     gene            complement(36671..37519)
                     /gene="folP"
                     /locus_tag="RN951_000160"
     CDS             complement(36671..37519)
                     /gene="folP"
                     /locus_tag="RN951_000160"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312083.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDX2525226.1"
                     /translation="MKLFAQGTSLDLSHPHVMGILNVTPDSFSDGGTHNSLIDAVKHA
                     NLMINAGATIIDVGGESTRPGAAEVSVEEELQRVIPVVEAIAQRFEVWISVDTSKPEV
                     IRESAKVGAHIINDIRSLSEPGALEAAAETGLPVCLMHMQGNPKTMQEAPKYDDVFAE
                     VNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGM
                     SRKSMIGQLLNVGPSERLSGSLACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAK
                     ENKRYE"
     gene            complement(37609..39543)
                     /gene="ftsH"
                     /locus_tag="RN951_000161"
     CDS             complement(37609..39543)
                     /gene="ftsH"
                     /locus_tag="RN951_000161"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDX2525227.1"
                     /translation="MAKNLILWLVIAVVLMSVFQSFGPSESNGRKVDYSTFLQEVNND
                     QVREARINGREINVTKKDSNRYTTYIPVQDPKLLDNLLTKNVKVVGEPPEEPSLLASI
                     FISWFPMLLLIGVWIFFMRQMQGGGGKGAMSFGKSKARMLTEDQIKTTFADVAGCDEA
                     KEEVAELVEYLREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISG
                     SDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLN
                     QMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDVRGREQILKVH
                     MRRVPLAPDIDAAIIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFEKAKDKI
                     MMGAERRSMVMTEAQKESTAYHEAGHAIIGRLVPEHDPVHKVTIIPRGRALGVTFFLP
                     EGDAISASRQKLESQISTLYGGRLAEEIIYGPEHVSTGASNDIKVATNLARNMVTQWG
                     FSEKLGPLLYAEEEGEVFLGRSVAKAKHMSDETARIIDQEVKALIERNYNRARQLLTD
                     NMDILHAMKDALMKYETIDAPQIDDLMARRDVRPPAGWEEPGASNNSGDNGSPKAPRP
                     VDEPRTPNPGNTMSEQLGDK"
     gene            complement(39643..40272)
                     /gene="rlmE"
                     /locus_tag="RN951_000162"
     CDS             complement(39643..40272)
                     /gene="rlmE"
                     /locus_tag="RN951_000162"
                     /EC_number="2.1.1.166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uridine(2552)-2'-O)-methyltransferase
                     RlmE"
                     /protein_id="HDX2525228.1"
                     /translation="MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQ
                     SDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRD
                     ELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGS
                     FVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRKP"
     gene            40398..40691
                     /gene="yhbY"
                     /locus_tag="RN951_000163"
     CDS             40398..40691
                     /gene="yhbY"
                     /locus_tag="RN951_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HDX2525229.1"
                     /translation="MNLSTKQKQHLKGLAHPLKPVVLLGSNGLTEGVLAEIEQALEHH
                     ELIKVKIATEDRETKTLIVEAIVRETGACNVQVIGKTLVLYRPTKERKISLPR"
     gene            complement(40847..41323)
                     /gene="greA"
                     /locus_tag="RN951_000164"
     CDS             complement(40847..41323)
                     /gene="greA"
                     /locus_tag="RN951_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006178768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HDX2525230.1"
                     /translation="MQAIPMTLRGAEKLREELDFLKSVRRPEIIAAIAEAREHGDLKE
                     NAEYHAAREQQGFCEGRIKDIEAKLSNAQVIDVTKMPNNGRVIFGATVTVLNLDSDEE
                     QTYRIVGDDEADFKQNLISVNSPIARGLIGKEEDDVVVIKTPGGEVEFEVIKVEYL"
     gene            41571..43004
                     /gene="dacB"
                     /locus_tag="RN951_000165"
     CDS             41571..43004
                     /gene="dacB"
                     /locus_tag="RN951_000165"
                     /EC_number="3.4.16.4"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001212660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HDX2525231.1"
                     /translation="MRFSRFIIGLTSCIAFSVQAANVDEYITQLPAGANLALMVQKVG
                     ASAPAIDYHSQQMALPASTQKVITALAALIQLGPDFRFTTTLETKGNVENGVLKGDLV
                     ARFGADPTLKRQDIRNMVATLKKSGVNQIDGNVLIDTSIFASHDKAPGWPWNDMTQCF
                     SAPPAAAIVDRNCFSVSLYSAPKPGDMAFIRVASYYPVTMFSQVRTLPRGSAEAQYCE
                     LDVVPGDLNRFTLTGCLPQRSEPLPLAFAVQDGASYAGAILKDELKQAGITWSGTLLR
                     QTQVNEPGTVVASKQSAPLHDLLKIMLKKSDNMIADTVFRMIGHARFNVPGTWRAGSD
                     AVRQILRQQAGVDIGNTIIADGSGLSRHNLIAPATMMQVLQYIAQHDNELNFISMLPL
                     AGYDGSLQYRAGLHQAGVDGKVSAKTGSLQGVYNLAGFITTASGQRMAFVQYLSGYAV
                     EPADQRNRRIPLVRFESRLYKDIYQNN"
     gene            complement(43190..44362)
                     /gene="cgtA"
                     /locus_tag="RN951_000166"
     CDS             complement(43190..44362)
                     /gene="cgtA"
                     /locus_tag="RN951_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Obg family GTPase CgtA"
                     /protein_id="HDX2525232.1"
                     /translation="MKFVDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGD
                     VWMEADENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTG
                     ETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRELLLELMLLA
                     DVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLI
                     EGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGTDPVENARIIISELEKYSQDLATK
                     PRWLVFNKIDLLDKVEAEEKAKAIAEALGWEDKYYLISAASGLGVKDLCWDVMTFIIE
                     NPVVQAEEAKQPEKVEFMWDDYHRQQLEEIAEEDDEDWDDDWDEDDEEGVEFIYKR"
     gene            complement(44378..45343)
                     /locus_tag="RN951_000167"
     CDS             complement(44378..45343)
                     /locus_tag="RN951_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012135318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDX2525233.1"
                     /translation="MKQQAGIGILLALTTAICWGALPIAMKQVLEVMEPPTIVFYRFL
                     MASIGLGAILAVKKRLPPLRVFRKPRWLILLAVATAGLFGNFILFSSSLQYLSPTASQ
                     VIGQLSPVGMMVASVFILKEKMRSTQVVGALMLLSGLVMFFNTSLVEIFTKLTDYTWG
                     VIFGVGAATVWVSYGVAQKVLLRRLASPQILFLLYTLCTIALFPLAKPGVIAQLSHWQ
                     LACLIFCGLNTLVGYGALAEAMARWQAAQVSAIITLTPLFTLFFSDLLSLAWPDFFAR
                     PMLNLLGYLGAFVVVAGAMYSAIGHRIWGGLRKHTTVVSQPRAGE"
     gene            complement(45470..45727)
                     /gene="rpmA"
                     /locus_tag="RN951_000168"
     CDS             complement(45470..45727)
                     /gene="rpmA"
                     /locus_tag="RN951_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HDX2525234.1"
                     /translation="MAHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTK
                     FHAGANVGCGRDHTLFAKADGKVKFEVKGPKNRKFISIEAE"
     gene            complement(45748..46059)
                     /gene="rplU"
                     /locus_tag="RN951_000169"
     CDS             complement(45748..46059)
                     /gene="rplU"
                     /locus_tag="RN951_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015960603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HDX2525235.1"
                     /translation="MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANG
                     EEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGIS
                     A"
     gene            46318..47289
                     /gene="ispB"
                     /locus_tag="RN951_000170"
     CDS             46318..47289
                     /gene="ispB"
                     /locus_tag="RN951_000170"
                     /EC_number="2.5.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="octaprenyl diphosphate synthase"
                     /protein_id="HDX2525236.1"
                     /translation="MNLEKINELTAQDMAGVNAAILEQLNSDVQLINQLGYYIVSGGG
                     KRIRPMIAVLAARAVGYEGNAHVTIAALIEFIHTATLLHDDVVDESDMRRGKATANAA
                     FGNAASVLVGDFIYTRAFQMMTSLGSLKVLEVMSEAVNVIAEGEVLQLMNVNDPDITE
                     ENYMRVIYSKTARLFEAAAQCSGILAGCTPEEEKGLQDYGRYLGTAFQLIDDLLDYNA
                     DGEQLGKNVGDDLNEGKPTLPLLHAMHHGTPEQAQMIRTAIEQGNGRHLLEPVLEAMN
                     ACGSLEWTRQRAEEEADKAIAALQVLPDTPWREALIGLAHIAVQRDR"
     gene            47517..47795
                     /gene="sfsB"
                     /locus_tag="RN951_000171"
     CDS             47517..47795
                     /gene="sfsB"
                     /locus_tag="RN951_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SfsB"
                     /protein_id="HDX2525237.1"
                     /translation="MESNFIDWHPADIIAGLRKKGTSMAAESRRNGLSSSTLANALSR
                     PWPKGEMIIAKALGTDPWVIWPSRYHDPQPHEFIYRTQLMRSYTKPKK"
     gene            complement(47843..49102)
                     /gene="murA"
                     /locus_tag="RN951_000172"
     CDS             complement(47843..49102)
                     /gene="murA"
                     /locus_tag="RN951_000172"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDX2525238.1"
                     /translation="MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNV
                     PKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVFCAPYDLVKTMRASIWALGSLVA
                     RFGQGQVSLPGGCTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDK
                     VSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGV
                     ERLGGGVYRVLPDRIETGTFLVAAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVG
                     EDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMH
                     VPELSRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRI
                     YHIDRGYERIEDKLRALGANIERVKGE"
     gene            complement(49157..49411)
                     /gene="ibaG"
                     /locus_tag="RN951_000173"
     CDS             complement(49157..49411)
                     /gene="ibaG"
                     /locus_tag="RN951_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417657.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BolA family iron metabolism protein IbaG"
                     /protein_id="HDX2525239.1"
                     /translation="MENNEIQSVLMNALSLQEVHVSGDGSHFQVIAVGELFDGMSRVK
                     KQQTVYGPLMEYIADNRIHAVSIKAYTPAEWARDRKLNGF"
     gene            complement(49571..49864)
                     /gene="mlaB"
                     /locus_tag="RN951_000174"
     CDS             complement(49571..49864)
                     /gene="mlaB"
                     /locus_tag="RN951_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312097.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance protein MlaB"
                     /protein_id="HDX2525240.1"
                     /translation="MSESLSWMQTGDTLALSGELDQDVLLPLWEMREEAVKGITCIDL
                     SRVSRVDTGGLALLLHLIDLAKKQGNNVTLQGVNDKVYTLAKLYNLPADVLPR"
     gene            complement(49864..50499)
                     /gene="mlaC"
                     /locus_tag="RN951_000175"
     CDS             complement(49864..50499)
                     /gene="mlaC"
                     /locus_tag="RN951_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding protein MlaC"
                     /protein_id="HDX2525241.1"
                     /translation="MFKRLMMVALLVIAPLSAATAADQTNPYKLMDEAAQKTFDRLKN
                     EQPQIRANPDYLRTIVDQELLPYVQVKYAGALVLGQYYKSATPAQREAYFAAFREYLK
                     QAYGQALAMYHGQTYQIAPEQPLGDKTIVPIRVTIIDPNGRPPVRLDFQWRKNSQTGN
                     WQAYDMIAEGVSMITTKQNEWGTLLRTKGIDGLTAQLKSISQQKITLEEKK"
     gene            complement(50518..51069)
                     /gene="mlaD"
                     /locus_tag="RN951_000176"
     CDS             complement(50518..51069)
                     /gene="mlaD"
                     /locus_tag="RN951_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipid asymmetry maintenance
                     protein MlaD"
                     /protein_id="HDX2525242.1"
                     /translation="MQTKKNEIWVGIFLLAALLAALFVCLKAANVTSIRTEPTYTLYA
                     TFDNIGGLKARSPVSIGGVVVGRVADITLDPKTYLPRVTLEIEQRYNHIPDTSSLSIR
                     TSGLLGEQYLALNVGFEDPELGTAILKDGDTIQDTKSAMVLEDLIGQFLYGSKGDDNK
                     NSGDAPAAAPGNNETTEPVGTTK"
     gene            complement(51074..51856)
                     /gene="mlaE"
                     /locus_tag="RN951_000177"
     CDS             complement(51074..51856)
                     /gene="mlaE"
                     /locus_tag="RN951_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014071945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance ABC transporter
                     permease subunit MlaE"
                     /protein_id="HDX2525243.1"
                     /translation="MLLNALASLGHKGIKTLRTFGRAGLMLFNALVGKPEFRKHAPLL
                     VRQLYNVGVLSMLIIVVSGVFIGMVLGLQGYLVLTTYSAETSLGMLVALSLLRELGPV
                     VAALLFAGRAGSALTAEIGLMRATEQLSSMEMMAVDPLRRVISPRFWAGVISLPLLTV
                     IFVAVGIWGGSLVGVSWKGIDSGFFWSAMQNAVDWRMDLVNCLIKSVVFAITVTWISL
                     FNGYDAIPTSAGISRATTRTVVHSSLAVLGLDFVLTALMFGN"
     gene            complement(51864..52673)
                     /gene="mlaF"
                     /locus_tag="RN951_000178"
     CDS             complement(51864..52673)
                     /gene="mlaF"
                     /locus_tag="RN951_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid ABC transporter ATP-binding protein
                     MlaF"
                     /protein_id="HDX2525244.1"
                     /translation="MEQSVANLVDMRDVSFTRGNRCIFDNISLTVPRGKITAIMGPSG
                     IGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTVRKRMSMLFQSGALFTDMNV
                     FDNVAYPLREHTQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIA
                     LEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAWIL
                     ADKKIVAHGSAQALQANPDPRVRQFLDGIADGPVPFRYPAGDYHADLLPGS"
     gene            52883..53860
                     /locus_tag="RN951_000179"
     CDS             52883..53860
                     /locus_tag="RN951_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HDX2525245.1"
                     /translation="MLLATALLIVGLLLVVYSADRLVFAASILCRTFGIPPLIIGMTV
                     VSIGTSLPEVIVSLAASLHEQRDLAVGTALGSNIINILLILGLAALVRPFTVHSDVLR
                     RELPLMLLVSVVAGSVLYDGQLSRSDGIFLLFLAVLWLLFIVKLARQAERQGTDSLTR
                     EQLAELPRDGGLPVAFLWLGIALIIMPVATRMVVDNATVLANYFAISELTMGLTAIAI
                     GTSLPELATAIAGVRKGENDIAVGNIIGANIFNIVIVLGLPALITPGEIDPLAYSRDY
                     SVMLLVSIIFALLCWRRSPQPGRGVGVLLTGGFIVWLAMLYWLSPILVE"
     gene            53874..54860
                     /gene="kdsD"
                     /locus_tag="RN951_000180"
     CDS             53874..54860
                     /gene="kdsD"
                     /locus_tag="RN951_000180"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase KdsD"
                     /protein_id="HDX2525246.1"
                     /translation="MSHVELQPGFDFQQAGKEVLAIERECLAELDQYINQNFTLACEK
                     MFWCKGKVVVMGMGKSGHIGRKMAATFASTGTPSFFVHPGEAAHGDLGMVTPQDVVIA
                     ISNSGESSEITALIPVLKRLHVPLICITGRPESSMARAADVHLCVKVAKEACPLGLAP
                     TSSTTATLVMGDALAVALLKARGFTAEDFALSHPGGALGRKLLLRVNDIMHTGDEIPH
                     VKKTASLRDALLEVTRKNLGMTVICDDNMMIEGIFTDGDLRRVFDMGVDVRQLSIADV
                     MTPGGIRVRPGILAVEALNLMQSRHITSVMVADGDHLLGVLHMHDLLRAGVV"
     gene            54881..55447
                     /gene="kdsC"
                     /locus_tag="RN951_000181"
     CDS             54881..55447
                     /gene="kdsC"
                     /locus_tag="RN951_000181"
                     /EC_number="3.1.3.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate-8-phosphatase KdsC"
                     /protein_id="HDX2525247.1"
                     /translation="MSKAGASLATCYGPVSADVIAKAENIRLLILDVDGVLSDGLIYM
                     GNNGEELKAFNVRDGYGIRCALTSDIEVAIITGRKAKLVEDRCATLGITHLYQGQSNK
                     LIAFSDLLEKLAIAPENVAYVGDDLIDWPVMEKVGLSVAVADAHPLLIPRADYVTRIA
                     GGRGAVREVCDLLLLAQGKLDEAKGQSI"
     gene            55444..56019
                     /gene="lptC"
                     /locus_tag="RN951_000182"
     CDS             55444..56019
                     /gene="lptC"
                     /locus_tag="RN951_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter periplasmic protein
                     LptC"
                     /protein_id="HDX2525248.1"
                     /translation="MSKARRWVIIVLSLAVLVMIGINMAEKDDTAQVVVNNNDPTYKS
                     EHTDTLVYNPEGALSYRLIAQHVEYYSDQAVSWFTQPVLTTFDKDKIPTWSVKADKAK
                     LTNDRMLYLYGHVEVNALVPDSQLRRITTDNAQINLVTQDVTSEDLVTLYGTTFNSSG
                     LKMRGNLRSKNAELIEKVRTSYEIQNKQTQP"
     gene            55988..56545
                     /gene="lptA"
                     /locus_tag="RN951_000183"
     CDS             55988..56545
                     /gene="lptA"
                     /locus_tag="RN951_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide ABC transporter
                     substrate-binding protein LptA"
                     /protein_id="HDX2525249.1"
                     /translation="MKFKTNKLSLNLVLASSLLAASIPAFAVTGDTDQPIHIESDQQS
                     LDMQGNVVTFTGNVIVTQGTIKINADKVVVTRPGGEQGKEVIDGYGKPATFYQMQDNG
                     KPVEGHASQMHYELAKDFVVLTGNAYLQQVDSNIKGDKITYLVKEQKMQAFSDKGKRV
                     TTVLVPSQLQDKNNKGQTPAQKKGN"
     gene            56552..57277
                     /gene="lptB"
                     /locus_tag="RN951_000184"
     CDS             56552..57277
                     /gene="lptB"
                     /locus_tag="RN951_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003861862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter ATP-binding protein"
                     /protein_id="HDX2525250.1"
                     /translation="MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTT
                     TFYMVVGIVPRDAGNIIIDDDDISLLPLHARARRGIGYLPQEASIFRRLSVYDNLMAV
                     LQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFIL
                     LDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAH
                     GTPTEILQDEHVKRVYLGEDFRL"
     gene            57325..58758
                     /gene="rpoN"
                     /locus_tag="RN951_000185"
     CDS             57325..58758
                     /gene="rpoN"
                     /locus_tag="RN951_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HDX2525251.1"
                     /translation="MKQGLQLRLSQQLAMTPQLQQAIRLLQLSTLELQQELQQALESN
                     PLLEQIDTHEEIDTRETQDSETLDTADALEQKEMPEELPLDASWDTIYTAGTPSGTSG
                     DYIDDELPVYQGETTQTLQDYLMWQVELTPFSDTDRAIATSIVDAVDETGYLTVPLED
                     ILESIGDEEIDIDEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLSQFDKTTPWLEEARL
                     IISDHLDLLANHDFRTLMRVTRLKEDVLKEAVNLIQSLDPRPGQSIQTGEPEYVIPDV
                     LVRKHNGHWTVELNSDSIPRLQINQHYASMCNNARNDGDSQFIRSNLQDAKWLIKSLE
                     SRNDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHS
                     PRGIFELKYFFSSHVNTEGGGEASSTAIRALVKKLIAAENPAKPLSDSKLTSLLSEQG
                     IMVARRTVAKYRESLSIPPSNQRKQLV"
     gene            58781..59068
                     /gene="hpf"
                     /locus_tag="RN951_000186"
     CDS             58781..59068
                     /gene="hpf"
                     /locus_tag="RN951_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome hibernation promoting factor"
                     /protein_id="HDX2525252.1"
                     /translation="MQLNITGNNVEITEALREFVTAKFAKLEQYFDRINQVYVVLKVE
                     KVTHTSDATLHVNGGEIHASAEGQDMYAAIDGLIDKLARQLTKHKDKLKQH"
     gene            59186..59677
                     /gene="ptsN"
                     /locus_tag="RN951_000187"
     CDS             59186..59677
                     /gene="ptsN"
                     /locus_tag="RN951_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS IIA-like nitrogen regulatory protein PtsN"
                     /protein_id="HDX2525253.1"
                     /translation="MTNNDTTLQLSSVLNRECTRSRVHCQSKKRALEIISELAAKQLS
                     LPPQVVFEAILTREKMGSTGIGNGIAIPHGKLEEDTLRAVGVFVQLETPIAFDAIDNQ
                     PVDLLFALLVPADQTKTHLHTLSLVAKRLADKTICRRLRAAQSDEELYQIITDTEGTP
                     DEA"
     gene            59723..60577
                     /gene="rapZ"
                     /locus_tag="RN951_000188"
     CDS             59723..60577
                     /gene="rapZ"
                     /locus_tag="RN951_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HDX2525254.1"
                     /translation="MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTL
                     ADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRL
                     HPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKREREL
                     TMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNF
                     IYQTRSYLELWLSMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRH
                     RTLEKRKP"
     gene            60574..60846
                     /gene="npr"
                     /locus_tag="RN951_000189"
     CDS             60574..60846
                     /gene="npr"
                     /locus_tag="RN951_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS phosphocarrier protein NPr"
                     /protein_id="HDX2525255.1"
                     /translation="MTVKQTVEITNKLGMHARPAMKLFELMQGFDAEVLLRNDEGTEA
                     EANSVIALLMLDSAKGRQIEVEATGPQEEEALAAVIALFNSGFDED"
     gene            61060..61692
                     /gene="yrbL"
                     /locus_tag="RN951_000190"
     CDS             61060..61692
                     /gene="yrbL"
                     /locus_tag="RN951_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP regulatory network protein YrbL"
                     /protein_id="HDX2525256.1"
                     /translation="MIRLSEQSPLGTGRHRKCYAHPEDAQRCIKIVYHRGDGGDKEIR
                     RELKYYAHLGRRLKDWSGIPRYHGTVETDCGTGYVYDVIADFDGKPSITLTEFAEQCR
                     YEEDIAQLRQLLKQLKRYLQDNRIVTMSLKPQNILCHRISESEVIPVVCDNIGESTLI
                     PLATWSKWCCLRKQERLWKRFIAQPALAIALQKDLQPRESKTLALTSREA"
     gene            complement(61689..62417)
                     /gene="mtgA"
                     /locus_tag="RN951_000191"
     CDS             complement(61689..62417)
                     /gene="mtgA"
                     /locus_tag="RN951_000191"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monofunctional biosynthetic peptidoglycan
                     transglycosylase"
                     /protein_id="HDX2525257.1"
                     /translation="MSKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAV
                     MVERQVSAWLHGNFRYVAHSDWVSMDQISPWMGLAVIAAEDQKFPEHWGFDVASIEKA
                     LAHNERNENRIRGASTISQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTV
                     YLNIAEFGDGVFGVEAAAQRYFHKPASKLTRSEAALLAAVLPNPLRFKVSSPSGYVRS
                     RQAWILRQMYQLGGEPFMQQHQLD"
     gene            complement(62414..63067)
                     /gene="elbB"
                     /locus_tag="RN951_000192"
     CDS             complement(62414..63067)
                     /gene="elbB"
                     /locus_tag="RN951_000192"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709007.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenoid biosynthesis glyoxalase ElbB"
                     /protein_id="HDX2525258.1"
                     /translation="MKKIGVILSGCGVYDGSEIHEAVLTLLAISRSGAQAVCFAPDKQ
                     QVDVINHLTGEAMTETRNVLIEAARITRGEIRPLAQADAAELDALIVPGGFGAAKNLS
                     NFASLGSECTVDRELKALAQAMHQAGKPLGFMCIAPAMLPKIFDFPLRLTIGTDIDTA
                     EVLEEMGAEHVPCPVDDIVVDEDNKIVTTPAYMLAQNIAEAASGIDKLVSRVLVLAE"
     gene            complement(63297..65633)
                     /gene="arcB"
                     /locus_tag="RN951_000193"
     CDS             complement(63297..65633)
                     /gene="arcB"
                     /locus_tag="RN951_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerobic respiration two-component sensor
                     histidine kinase ArcB"
                     /protein_id="HDX2525259.1"
                     /translation="MKQIRLLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTM
                     VLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQLEESRQRLSRLVQKLEEMRERDL
                     SLNVQLKDNIAQLNQEIAVREKAEAELQETFGQLKIEIKEREETQIQLEQQSSFLRSF
                     LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPADVYSPEAAAKVIETDEK
                     VFRHNVSLTYEQWLDYPDGRKACFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDAL
                     ERASRDKTTFISTISHELRTPLNGIVGLSRILLDTELTAEQEKYLKTIHVSAVTLGNI
                     FNDIIDMDKMERRKVQLDNQPVDFTSFLADLENLSALQAQQKGLRFNLEPTLPLPHQV
                     ITDGTRLRQILWNLISNAVKFTQQGQVTVRVRYDEGDMLHFEVEDSGIGIPQDELDKI
                     FAMYYQVKDSHGGKPATGTGIGLAVSRRLAKNMGGDITVTSEQGKGSTFTLTIHAPSV
                     AEEVDDAFDEDDMPLPALNVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKAALEMFK
                     PGEYDLVLLDIQLPDMTGLDISRELTKRYPREDLPPLVALTANVLKDKQEYLNAGMDD
                     VLSKPLSVPALTAMIKKFWDTQDDEESTVTTEENSKSEALLDIPMLEQYLELVGPKLI
                     TDGLAVFEKMMPGYVSVLESNLTAQDKKGIVEEGHKIKGAAGSVGLRHLQQLGQQIQS
                     PDLPAWEDNVGEWIEEMKEEWRHDVEVLKAWVAKATKK"
     gene            complement(65729..66658)
                     /locus_tag="RN951_000194"
     CDS             complement(65729..66658)
                     /locus_tag="RN951_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312117.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HDX2525260.1"
                     /translation="MQLQKLVNMFGGDLTRRYGQKVHKLTLHGGFSCPNRDGTIGRGG
                     CTFCNVASFADEAQQHRSIAEQLAHQANLVNRAKRYLAYFQAYTSTFAEVQVLRSMYQ
                     QAVSQANIVGLCVGTRPDCVPDAVLDLLCEYKDQGYEVWLELGLQTAHDKTLHRINRG
                     HDFACYQRTTQLARQRGLKVCSHLIVGLPGEGQAECLQTLERVVETGVDGIKLHPLHI
                     VKGSIMAKAWEAGRLNGIELEDYTLTAGEMIRHTPPEVIYHRISASARRPTLLAPLWC
                     ENRWTGMVELDRYLNEHGVQGSALGRPWLPPTE"
     gene            67333..71793
                     /gene="gltB"
                     /locus_tag="RN951_000195"
     CDS             67333..71793
                     /gene="gltB"
                     /locus_tag="RN951_000195"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase large subunit"
                     /protein_id="HDX2525261.1"
                     /translation="MLYDKSLERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGA
                     ILADGKTGDGCGLLLQKPDRFFRIVAQERGWRLAKNYAVGMLFLNKDPELAAAARRIV
                     EEELQRETLSIVGWRDVPTNEGVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIA
                     RRRIEKRLEADKDFYVCSLSNLVNIYKGLCMPTDLPRFYLDLADLRLESAICLFHQRF
                     STNTVPRWPLAQPFRYLAHNGEINTITGNRQWARARTYKFQTPLIPDLHDAAPFVNET
                     GSDSSSMDNMLELLLAGGMDIIRAMRLLVPPAWQNNPDMDPELRAFFDFNSMHMEPWD
                     GPAGIVMSDGRFAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVG
                     PGELMVIDTRSGRILHSAETDDDLKSRHPYKEWMEKNVRRLVPFEDLSDEEVGSRELD
                     DDTLASYQKQFNYSAEELDSVIRVLGENGQEAVGSMGDDTPFAVLSSQPRIIYDYFRQ
                     QFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYSDFKQLT
                     TMKEEHYRADTLDITFDVTKTTLEATVKELCDKAEKMVRSGTVLLVLSDRNIAKDRLP
                     VPAPMAVGAIQTRLVDQSLRCDANIIVETASARDPHHFAVLLGFGATAIYPYLAYETL
                     GRLVDTHAIAKDYRTVMLNYRNGINKGLYKIMSKMGISTIASYRCSKLFEAVGLHDDV
                     VGLCFQGAVSRIGGASFEDFQQDLLNLSKRAWLARKPISQGGLLKYVHGGEYHAYNPD
                     VVRTLQQAVQSGEYSDYQEYAKLVNERPATTLRDLLAITPGENAVNIADVEPASELFK
                     RFDTAAMSIGALSPEAHEALAEAMNSIGGNSNSGEGGEDPARYGTNKVSRIKQVASGR
                     FGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVPGVTLISPPPHH
                     DIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGT
                     GASPLSSVKYAGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIIKAAILGAE
                     SFGFGTGPMVALGCKYLRICHLNNCATGVATQDDKLRKNHYHGLPFKVTNYFEFIARE
                     TRELMAQLGVTRLVDLIGRTDLLKELDGFTAKQQKLALSKLLETAEPHPGKALYCTEN
                     NPPFDNGLLNAQLLQQAKPFVDERQSKTFWFDIRNTDRSVGASLSGYIAQTHGDQGLA
                     ADPIKAYFNGTAGQSFGVWNAGGVELYLTGDANDYVGKGMAGGLIAIRPPVGSAFRSH
                     EASIIGNTCLYGATGGRLYAAGRAGERFGVRNSGAITVVEGIGDNGCEYMTGGIVCIL
                     GKTGVNFGAGMTGGFAYVLDESGDFRKRVNPELVEVLSVDDLAIHEEHLRGLITEHVQ
                     HTGSQRGEEILANWSTFATKFALVKPKSSDVKALLGHRSRSAAELRVQAQ"
     gene            71806..73224
                     /gene="gltD"
                     /locus_tag="RN951_000196"
     CDS             71806..73224
                     /gene="gltD"
                     /locus_tag="RN951_000196"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001540975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase subunit GltD"
                     /protein_id="HDX2525262.1"
                     /translation="MSQNVYQFIDLQRVDPPKKPLKIRKIEFVEIYEPFSEGQAKAQA
                     DRCLSCGNPYCEWKCPVHNYIPNWLKLANEGRIFEAAELSHQTNTLPEVCGRVCPQDR
                     LCEGSCTLNDEFGAVTIGNIERYINDKAFEMGWRPDMSGVKQTGKKVAIIGAGPAGLA
                     CADVLTRNGVQAVVFDRHPEIGGLLTFGIPAFKLEKEVMTRRREIFTGMGIEFKLNTE
                     VGRDVQLDDLLSDYDAVFLGVGTYQSMRGGLENEDADGVYAALPFLIANTKQLMGFGE
                     TRDEPFVSMEGKRVVVLGGGDTAMDCVRTSVRQGAKHVTCAYRRDEENMPGSRREVKN
                     AREEGVEFKFNVQPLGIEVNGNGKVSGVKMVRTEMGEPDAKGRRRAEIVAGSEHIVPA
                     DAVIMAFGFRPHNMEWLAKHSVELDSQGRIIAPEGSDNAFQTSNPKIFAGGDIVRGSD
                     LVVTAIAEGRKAADGIMNWLEV"
     gene            73408..73887
                     /locus_tag="RN951_000197"
     CDS             73408..73887
                     /locus_tag="RN951_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005085993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1016 family protein"
                     /protein_id="HDX2525263.1"
                     /translation="MESLSERTSTGYQQIHDGIIHLVDSARTETVRSVNALMTATYWE
                     IGRRIVEFEQGGEARAAYGAQLIKRLSKDLSLRYKRGFSAKNLRQMRLFYLFFQHVEI
                     RQTVSGELTPLGIPQTPSAEFPSAKIWQTLSAKLRGCLIFPQLLYCISYFRFVYSCK"
     gene            73904..74209
                     /locus_tag="RN951_000198"
     CDS             73904..74209
                     /locus_tag="RN951_000198"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDX2525264.1"
                     /translation="MIYIEQLELIHKSGDVLYPVKITRKSSGKTAFHLVPFGLNKTHD
                     LLEVEDASEAIRLVIDERHSIRCSTLTATITNKKGKRIKRTGIYSIKGVNIKEYNVR"
     gene            complement(74285..74749)
                     /locus_tag="RN951_000199"
     CDS             complement(74285..74749)
                     /locus_tag="RN951_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HDX2525265.1"
                     /translation="MMMGEVQSLPSAGLHPALQDALTLALAARPQEKAPGRYELQGDN
                     IFMNVMTFNTQSPVEKKAELHEQYIDIQLLLNGEERILFGMAGTARQCEEFHHEDDYQ
                     LCSTIDNEQAIILKPGMFAVFMPGEPHKPGCVVGEPGEIKKVVVKVKADLMA"
     gene            complement(74746..75621)
                     /gene="nanK"
                     /locus_tag="RN951_000200"
     CDS             complement(74746..75621)
                     /gene="nanK"
                     /locus_tag="RN951_000200"
                     /EC_number="2.7.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312122.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine kinase"
                     /protein_id="HDX2525266.1"
                     /translation="MTTLAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPEALRDA
                     LSALVSPLQAHVQRVAIASTGIIRDGSLLALNPHNLGGLLHFPLVKTLEQLTDLPTIA
                     INDAQAAAWAEYQALEGDVTEMVFITVSTGVGGGVVSGGKLLTGPGGLAGHIGHTLAD
                     PHGPVCGCGRTGCVEAIASGRGIAAAAQGELAGADARTIFTRAGQGDEQAQQLIHRSA
                     RTLARLIADIKATTDCQCVVVGGSVGLAEGYLALVETYLAQEPAAFHVDLLAAHYRHD
                     AGLLGAALLAQGEKL"
     gene            complement(75618..76307)
                     /locus_tag="RN951_000201"
     CDS             complement(75618..76307)
                     /locus_tag="RN951_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDX2525267.1"
                     /translation="MSLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQ
                     AGAVAIRIEGVANLQATRAVVSVPIIGIVKRDLEDSPVRITAYIEDVDALAQAGADII
                     AIDGTDRPRPVPVETLLARIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTP
                     ETPEEPDLALVKTLSDAGCRVIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQ
                     WYNTAMKKAVL"
     gene            complement(76355..77845)
                     /gene="nanT"
                     /locus_tag="RN951_000202"
     CDS             complement(76355..77845)
                     /gene="nanT"
                     /locus_tag="RN951_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312124.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialic acid transporter NanT"
                     /protein_id="HDX2525268.1"
                     /translation="MSTTTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLT
                     EVQGEFGLTTVQAASLISAAFISRWFGGLMLGAMGDRYGRRLAMVTSIVLFSAGTLAC
                     GFAPGYITMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVA
                     AQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHAGKAPVRTMVDILY
                     RGEHRIANIVMTLAAATALWFCFAGNLQNAAIVAVLGLLCAAIFISFMVQSTGKRWPT
                     GVMLMVVVLFAFLYSWPIQALLPTYLKTDLAYNPHTVANVLFFSGFGAAVGCCVGGFL
                     GDWLGTRKAYVCSLLASQLLIIPVFAIGGANVWVLGLLLFFQQMLGQGIAGILPKLIG
                     GYFDTDQRAAGLGFTYNVGALGGALAPIIGALIAQRLDLGTALASLSFSLTFVVILLI
                     GLDMPSRVQRWLRPEALRTHDAIDGKPFSGAVPFGSAKNDLVKTKS"
     gene            complement(77954..78847)
                     /gene="nanA"
                     /locus_tag="RN951_000203"
     CDS             complement(77954..78847)
                     /gene="nanA"
                     /locus_tag="RN951_000203"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HDX2525269.1"
                     /translation="MATNLRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYV
                     GGSTGEAFVQSLSEREQVLEIVAEEAKGQIKLIAHVGCVSTAESQQLAASAKRYGFDA
                     VSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPG
                     VGALKQTSGDLYQMEQIRREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQ
                     GIVKALKEGDIQTAQKLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFGP
                     VDEKYLPELKALAQQLMQERG"
     gene            complement(78969..79760)
                     /gene="nanR"
                     /locus_tag="RN951_000204"
     CDS             complement(78969..79760)
                     /gene="nanR"
                     /locus_tag="RN951_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312126.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NanR"
                     /protein_id="HDX2525270.1"
                     /translation="MGLMNAFDSQTEDSSPAIGRNLRSRPLARKKLSEMVEEELEQMI
                     RRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADT
                     IIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQ
                     SLDNNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVADQALHEHNNVS
                     YQQHIAIVDAIRRHDPDEADRALQSHLNSVSATWHAFGQTTNKKK"
     gene            80140..81507
                     /gene="dcuC"
                     /locus_tag="RN951_000205"
     CDS             80140..81507
                     /gene="dcuC"
                     /locus_tag="RN951_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuC"
                     /protein_id="HDX2525271.1"
                     /translation="MFGIIISVIVLITMGYLILKNYKPQVVLAAAGIFLMMCGVWLGF
                     GGVLDPAKSSGYLIVDIYNEILRMLSNRIAGLGLSIMAVGGYARYMERIGASRAMVSL
                     LSRPLKLIRSPYIILSATYVIGQIMAQFITSASGLGMLLMVTLFPTLVSLGVSRLSAV
                     AVIATTMSIEWGILETNSIFAAQVAGMKIATYFFHYQLPVASCVIISVAISHFFVQRA
                     FDKKDKNINHEQAEQKALDNVPPLYYAILPVMPLILMLGSLFLAHIGLMQSELHLVVV
                     MLLSLTVTMFVEFFRKHNLRETMDDVQAFFDGMGTQFANVVTLVVAGEIFAKGLTTIG
                     TVDAVIRGAEHSGLGGIGVMIIMALVIAICAIVMGSGNAPFMSFASLIPNIAAGLHVP
                     AVVMIMPMHFATTLARAVSPITAVVVVTSGIAGVSPFAVVKRTAIPMAVGFVVNMIAT
                     ITLFY"
     gene            complement(81550..82047)
                     /gene="sspB"
                     /locus_tag="RN951_000206"
     CDS             complement(81550..82047)
                     /gene="sspB"
                     /locus_tag="RN951_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP protease specificity-enhancing factor"
                     /protein_id="HDX2525272.1"
                     /translation="MDLSQLTPRRPYLLRAFYEWLLDNQLTPHLVVDVTLPGVQVPME
                     YARDGQIVLNIAPRAVGNLELANDEVRFNARFGGIPRQVSVPLAAVLAIYARENGAGT
                     MFEPEAAYDEDTSIMNDEEASADNETVMSVIDGDKPDHDDDTHPDDEPPQPPRGGRPA
                     LRVVK"
     gene            complement(82053..82691)
                     /gene="sspA"
                     /locus_tag="RN951_000207"
     CDS             complement(82053..82691)
                     /gene="sspA"
                     /locus_tag="RN951_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stringent starvation protein A"
                     /protein_id="HDX2525273.1"
                     /translation="MAVAANKRSVMTLFSGPTDIYSHQVRIVLAEKGVSFEIEHVEKD
                     NPPQDLIDLNPNQSVPTLVDRELTLWESRIIMEYLDERFPHPPLMPVYPVARGESRLY
                     MHRIEKDWYTLMNTIINGSASEADAARKQLREELLAIAPVFGQKPYFLSDEFSLVDCY
                     LAPLLWRLPQLGIEFSGPGAKELKGYMTRVFERDSFLASLTEAEREMRLGRS"
     gene            complement(83086..83478)
                     /gene="rpsI"
                     /locus_tag="RN951_000208"
     CDS             complement(83086..83478)
                     /gene="rpsI"
                     /locus_tag="RN951_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDX2525274.1"
                     /translation="MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETA
                     RMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAG
                     FVTRDARQVERKKVGLRKARRRPQFSKR"
     gene            complement(83494..83922)
                     /gene="rplM"
                     /locus_tag="RN951_000209"
     CDS             complement(83494..83922)
                     /gene="rplM"
                     /locus_tag="RN951_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010847760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HDX2525275.1"
                     /translation="MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEY
                     TPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIE
                     IAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI"
     gene            complement(84141..85268)
                     /gene="zapE"
                     /locus_tag="RN951_000210"
     CDS             complement(84141..85268)
                     /gene="zapE"
                     /locus_tag="RN951_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapE"
                     /protein_id="HDX2525276.1"
                     /translation="MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYQELINSTP
                     PAPRTSGLMARVGKLWGKREDTKHTPVRGLYMWGGVGRGKTWLMDLFYQSLPGERKQR
                     LHFHRFMLRVHEELTALQGQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLM
                     KALFTRGITLVATSNIPPDELYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTL
                     TQAHLWLSPLNDETRAQMDKLWLALAGAKRENSPTLEINHRPLATMGVENQTLAVSFT
                     TLCVDARSQHDYIALSRLFHTVMLFDVPVMTRLMESEARRFIALVDEFYERHVKLVVS
                     AEVPLYEIYQGDRLKFEFQRCLSRLQEMQSEEYLKREHLAG"
     gene            85462..85860
                     /locus_tag="RN951_000211"
     CDS             85462..85860
                     /locus_tag="RN951_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1043 family protein"
                     /protein_id="HDX2525277.1"
                     /translation="MTWEYALIGLVVGIIIGAVAMRFGNRKLRQQQALQYELEKNKAE
                     LDEYREELVSHFARSAELLDTMAHDYRQLYQHMAKSSSSLLPELSAEANPFRNRLAES
                     EASNDQAPVQMPRDYSEGASGLLRTGAKRD"
     gene            86014..87381
                     /gene="degQ"
                     /locus_tag="RN951_000212"
     CDS             86014..87381
                     /gene="degQ"
                     /locus_tag="RN951_000212"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegQ"
                     /protein_id="HDX2525278.1"
                     /translation="MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAP
                     MLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASKG
                     YVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSD
                     KLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGAL
                     LNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEM
                     SADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIAT
                     TEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGI
                     KIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGNESI
                     YLLMR"
     gene            87471..88538
                     /gene="degS"
                     /locus_tag="RN951_000213"
     CDS             87471..88538
                     /gene="degS"
                     /locus_tag="RN951_000213"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane-stress sensor serine
                     endopeptidase DegS"
                     /protein_id="HDX2525279.1"
                     /translation="MFVKLLRSVAIGLIVGAILLVAMPSLRSLNPLSTPQFDSTDETP
                     ASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD
                     QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGN
                     PYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTL
                     SFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQGGGI
                     DQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVV
                     VMRDDKQLTLQVTIQEYPATN"
     gene            complement(88601..89539)
                     /gene="mdh"
                     /locus_tag="RN951_000214"
     CDS             complement(88601..89539)
                     /gene="mdh"
                     /locus_tag="RN951_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HDX2525280.1"
                     /translation="MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAV
                     DLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLV
                     QQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAE
                     LKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKA
                     GGGSATLSMGQAAARFGLSLVRALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVE
                     ERKSIGTLSAFEQNALEGMLDTLKKDIALGEEFVNK"
     gene            89974..90444
                     /gene="argR"
                     /locus_tag="RN951_000215"
     CDS             89974..90444
                     /gene="argR"
                     /locus_tag="RN951_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ArgR"
                     /protein_id="HDX2525281.1"
                     /translation="MRSSAKQEELVKAFKALLKEEKFSSQGEIVAALQEQGFDNINQS
                     KVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSP
                     GAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPANGFTVKDLYEAILELFDQEL"
     gene            90809..91072
                     /gene="yhcN"
                     /locus_tag="RN951_000216"
     CDS             90809..91072
                     /gene="yhcN"
                     /locus_tag="RN951_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417705.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid stress response protein YhcN"
                     /protein_id="HDX2525282.1"
                     /translation="MKIKTTVAALSVLSVLSFGAFAADSIDAAQAQNREAIGTVSVSG
                     VASSPMDMREMLNKKAEEKGATAYQITEARSGDTWHATAELYK"
     gene            complement(91128..91400)
                     /locus_tag="RN951_000217"
     CDS             complement(91128..91400)
                     /locus_tag="RN951_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="barstar family protein"
                     /protein_id="HDX2525283.1"
                     /translation="MNIYTFDFDEIESQEDFYRDFSQTFGLAKDKVRDLDSLWDVLMN
                     DVLPLPLEIEFVHLGEKTRRRFGALILLFDEAEEELEGHLRFNVRH"
     gene            complement(91492..93459)
                     /gene="aaeB"
                     /locus_tag="RN951_000218"
     CDS             complement(91492..93459)
                     /gene="aaeB"
                     /locus_tag="RN951_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeB"
                     /protein_id="HDX2525284.1"
                     /translation="MGIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAA
                     IVAAGPAFAAGGEPYSGAIRYRGFLRIIGTFIGCIAGLVIIIAMIRAPLLMILVCCIW
                     AGFCTWISSLVRIENSYAWGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCA
                     IMADLLFSPRSIKQEVDRELESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTALQ
                     GMRSNLNMESSRWARANRRLKAINTLSLTLITQSCETYLIQNTRPELITDTFREFFDT
                     PVETAQDVHKQLKRLRRVIAWTGERETPVTIYSWVAAATRYQLLKRGVISNTKINATE
                     EEILQGEPEVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGSGAMVMIAVVTS
                     LAMRLPNPRMVAIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCISLAVLGFFLGIE
                     VQKRRLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCVLAFTVILLVRDKSR
                     DRTGRVLLNQFVSAAVSAMTTNVARRKENHLPALYQQLFLLMNKFPGDLPKFRLALTM
                     IIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVISARSDDKRRRYFGQLLEELEIYQEK
                     LRIWQAPPQVTEPVNRLAGMLHKYQHALTDS"
     gene            complement(93465..94397)
                     /gene="aaeA"
                     /locus_tag="RN951_000219"
     CDS             complement(93465..94397)
                     /gene="aaeA"
                     /locus_tag="RN951_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeA"
                     /protein_id="HDX2525285.1"
                     /translation="MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFS
                     ADVVAIAPDVSGLITQVNVHDNQLVKKGQILFTIDQPRYQKALEEAQADVAYYQVLAQ
                     EKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAP
                     ADGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGS
                     NKVLKGTVDSVAAGVTNASSTRDDKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWP
                     AGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG"
     gene            complement(94405..94608)
                     /locus_tag="RN951_000220"
     CDS             complement(94405..94608)
                     /locus_tag="RN951_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AaeX family protein"
                     /protein_id="HDX2525286.1"
                     /translation="MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRVLVPTGIYDFV
                     WHPALFNTALYCCLFYLISRLFV"
     gene            94791..95720
                     /gene="aaeR"
                     /locus_tag="RN951_000221"
     CDS             94791..95720
                     /gene="aaeR"
                     /locus_tag="RN951_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AaeR"
                     /protein_id="HDX2525287.1"
                     /translation="MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDEL
                     QVKLLNRSTRSIGLTEAGRIYYQGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTM
                     AQNVLAGLTAKMLKEYPGLSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGA
                     MPMVVCAAKSYLTQYGIPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRF
                     VTNDPMTLVRWLTAGAGIAYVPLMWVINEINRGELEILLPRYQSDPRPVYALYTEKDK
                     LPLKVQVVINSLTDYFVEVGKLFQEMHGRGKEK"
     gene            complement(95854..97299)
                     /gene="tldD"
                     /locus_tag="RN951_000222"
     CDS             complement(95854..97299)
                     /gene="tldD"
                     /locus_tag="RN951_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease TldD"
                     /protein_id="HDX2525288.1"
                     /translation="MSLNLVSEQLLAANGLKHQDLFAILGQLAERRLDYGDLYFQSSY
                     HESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRD
                     SGDGKVQTLGAVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLS
                     GVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGASGGGGRFGYEFFLADLD
                     GEVRADAWAKEAVRMALVNLSAVAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRR
                     GTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQ
                     DKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFG
                     GGQVDITSGKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNG
                     VGVCGKEGQSLPVGVGQPTLKVDNLTVGGTA"
     gene            complement(97729..101529)
                     /gene="yhdP"
                     /locus_tag="RN951_000223"
     CDS             complement(97729..101529)
                     /gene="yhdP"
                     /locus_tag="RN951_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA2 domain-containing protein YhdP"
                     /protein_id="HDX2525289.1"
                     /translation="MRRLPGILLLTGAALVVIAALLVSGLRIALPHLDAWRPEILNKI
                     ESATGMPVEASQLSASWQNFGPTLEAHDIRAELKDGGEFSVKRVTLALDVWQSLLHMR
                     WQFRDLTFWQLRFRTNTPITSGGSDDSLEASHISDLFLRQFDHFDLRDSEVSFLTPSG
                     QRAELAIPQLTWLNDPRRHRAEGLVSLSSLTGQHGVMQVRMDLRDDEGLLSNGRVWLQ
                     ADDIDLKPWLGKWMQDNIALETAQFSLEGWMTIDKGDVTGGDVWLKQGGASWLGEKQT
                     HTLSVDNLTAHITRENPGWQFSIPDTRITMDGKPWPSGALTLAWIPEQDVGGKDNKRS
                     DELRIRASNLELAGLEGIRPLAAKLSPALGDVWRSTQPSGKINTLALDIPLQAADKTR
                     FQASWSDLAWKQWKLLPGAEHFSGTLSGSVENGLLTASMKQAKMPYETVFRAPLEIAD
                     GQATISWLNNNKGFQLDGRNIDVKAKAVHARGGFRYLQPANDEPWLGILAGISTDDGS
                     QAWRYFPENLMGKDLVDYLSGAIQGGEADNATLVYGGNPQLFPYKHNEGQFEVLVPLR
                     NAKFAFQPDWPALTNLDIELDFINDGLWMKTDGVNLGGVRASNLTAVIPDYSKEKLLI
                     DADIKGPGKAVGPYFDETPLKDSLGATLQELQLDGDVNARLHLDIPLNGELVTAKGEV
                     TLRNNSLFIKPLDSTLKNLSGKFSFINSDLQSEPLTASWFNQPLNVDFSTKEGAKAYQ
                     VAVNLNGNWQPAKTGVLPEAVNEALSGSVAWDGKVGIDLPYHAGATYNIELNGDLKNV
                     SSHLPSPLAKPAGEPLAVNVKVDGNLNSFELTGQAGADNHFNSRWLLGQKLTLDRAIW
                     AADSKTLPPLPEQSGVELNMPPMNGAEWLALFQKGAAESVGGAASFPQHITLRTPMLS
                     LGNQQWNNLSIVSQPTANGTLVEAQGREINATLAMRNNAPWLANIKYLYYNPSVAKTR
                     GDSTPSSPFPTTERINFRGWPDAQIRCTECWFWGQKFGRIDSDITISGDTLTLTNGLI
                     DTGFSRLTADGEWVNNPGNERTSLKGKLRGQKIDAAAEFFGVTTPIRQSSFNVDYDLH
                     WRKAPWQPDEATLNGIIHTQLGKGEITEINTGHAGQLLRLLSVDALMRKLRFDFRDTF
                     GEGFYFDSIRSTAWIKDGVMHTDDTLVDGLEADIAMKGSVNLVRRDLNMEAVVAPEIS
                     ATVGVAAAFAVNPIVGAAVFAASKVLGPLWSKVSILRYHISGPLDDPQINEVLRQPRK
                     EKAQ"
     gene            complement(101597..103066)
                     /gene="rng"
                     /locus_tag="RN951_000224"
     CDS             complement(101597..103066)
                     /gene="rng"
                     /locus_tag="RN951_000224"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease G"
                     /protein_id="HDX2525290.1"
                     /translation="MTAELLVNVTPSETRVAYIDGGILQEIHIEREARRGIVGNIYKG
                     RVSRVLPGMQAAFVDIGLDKAAFLHASDIMPHTECVAGEEQKQFTVRDISELVRQGQD
                     LMVQVVKDPLGTKGARLTTDITLPSRYLVFMPGASHVGVSQRIESESERERLKKVVAE
                     YCDEQGGFIIRTAAEGVGEAELASDAAYLKRVWTKVMERKKRPQTRYQLYGELALAQR
                     VLRDFADAELDRIRVDSRLTYEALLEFTSEYIPEMTSKLEHYTGRQPIFDLFDVENEI
                     QRALERKVELKSGGYLIIDQTEAMTTVDINTGAFVGHRNLDDTIFNTNIEATQAIARQ
                     LRLRNLGGIIIIDFIDMNNEDHRRRVLHSLEQALSKDRVKTSVNGFSALGLVEMTRKR
                     TRESIEHVLCNECPTCHGRGTVKTVETVCYEIMREIVRVHHAYDSDRFLVYASPAVAE
                     ALKGEESHSLAEVEIFVGKQVKVQIEPLYNQEQFDVVMM"
     gene            complement(103056..103649)
                     /gene="yhdE"
                     /locus_tag="RN951_000225"
     CDS             complement(103056..103649)
                     /gene="yhdE"
                     /locus_tag="RN951_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase YhdE"
                     /protein_id="HDX2525291.1"
                     /translation="MTSLYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQY
                     VVRLAREKARAGVAQTAKDLPVLGADTIVILNGEVLEKPRDAEHAAQMLRKLSGQTHQ
                     VMTAVALADSQHILDCLVVTDVTFRTLTDEDIAGYVASDEPLDKAGAYGIQGLGGCFV
                     RKINGSYHAVVGLPLVETYELLSNFNALREKRDKHDG"
     gene            complement(103658..104146)
                     /gene="mreD"
                     /locus_tag="RN951_000226"
     CDS             complement(103658..104146)
                     /gene="mreD"
                     /locus_tag="RN951_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001487551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HDX2525292.1"
                     /translation="MASYRSQGRWVIWLSFLIALLLQIMPWPDNLIVFRPNWVLLILL
                     YWILALPHRVNVGTGFVMGAILDLISGSTLGVRVLAMSIIAYLVALKYQLFRNLALWQ
                     QALVVMLLSLVVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFA
                     VQ"
     gene            complement(104146..105249)
                     /gene="mreC"
                     /locus_tag="RN951_000227"
     CDS             complement(104146..105249)
                     /gene="mreC"
                     /locus_tag="RN951_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HDX2525293.1"
                     /translation="MKPIFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDT
                     AVSPFYFVSNAPRELLDGVSQTLASRDQLELENRALRQELLLKNSELLMLGQYKQENA
                     RLRELLGSPLRQDEQKMVTQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQ
                     VVAVAKLTSRVLLICDATHALPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGD
                     VLVTSGLGGRFPEGYPVAVVSSVKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNG
                     ANPMTPEEVHRVANERLMQMMPQVLPSPDAMGPKLPEPATGIAQPTPQQPATGNAATA
                     PAAPTQPAANRSPQRATPPQSGAQPPARAPGGQ"
     gene            complement(105315..106358)
                     /gene="mreB"
                     /locus_tag="RN951_000228"
     CDS             complement(105315..106358)
                     /gene="mreB"
                     /locus_tag="RN951_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000913396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreB"
                     /protein_id="HDX2525294.1"
                     /translation="MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQD
                     RAGSPKSVAAVGHDAKQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNS
                     FMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATG
                     SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERI
                     KHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALE
                     QCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALE
                     MIDMHGGDLFSEE"
     gene            complement(106663..108603)
                     /gene="csrD"
                     /locus_tag="RN951_000229"
     CDS             complement(106663..108603)
                     /gene="csrD"
                     /locus_tag="RN951_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase E specificity factor CsrD"
                     /protein_id="HDX2525295.1"
                     /translation="MRLTTKFSAFVTLLTGLTIFVTLLGCSLSFYNAIQYKFSHRVQA
                     VATAIDTHLVSNDFSTLRPQITELMMSADIVRVDLLHGDKQVYTLARNGSYRPVGSSD
                     LFRELSVPLIKHPGMSLRLVYQDPMGNYFHSLMTTAPLTGAIGFIIVMLFLAVRWLQR
                     QLAGQELLETRATRILNGERGSNVLGTIYEWPPRTSSALDTLLREIQNAREQHSRLDT
                     LIRSYAAQDVKTGLNNRLFFDNQLATLLEDQEKVGTHGIVMMIRLPDFNMLSDTWGHS
                     QVEEQFFTLTNLLSTFMMRYPGALLARYHRSDFAALLPHRTLKEAESIAGQLIKAVDT
                     LPNNKMLDRDDMIHIGICAWRSGQDTEQVMEHAESATRNAGLQGGNSWAIYDDSLPEK
                     GRGNVRWRTLIEQMLSRGGPRLYQKPAVTCEGQVHHRELMCRIFDGNEEVSSAEYMPM
                     VLQFGLSEEYDRLQISRLIPLLRYWPEENLAIQVTVESLIRPRFQRWLRDTLMQCEKS
                     QRKRIIIELAEADVGQHISRLQPVIRLVNALGVRVAVNQAGLTLVSTSWIKELNVELL
                     KLHPGLVRNIEKRTENQLLVQSLVEACSGTSTQVYATGVRSRSEWQTLIQRGVTGGQG
                     DFFASSQPLDTNVKKYSQRYSV"
     gene            108755..109729
                     /locus_tag="RN951_000230"
     CDS             108755..109729
                     /locus_tag="RN951_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDX2525296.1"
                     /translation="MQALLLEQQDGKTLASVQTLDESRLPEGDVTVDVHWSSLNYKDA
                     LAITGKGKIIRNFPMIPGIDFAGTVRTSEDPRFHAGQEVLLTGWGVGENHWGGLAEQA
                     RVKGDWLVAMPQGLDARKAMIIGTAGFTAMLCVMALEDAGVRPQDGEIVVTGASGGVG
                     STAVALLHKLGYQVVAVSGRESTHEYLKSLGASRVLPRDEFAESRPLEKQVWAGAIDT
                     VGDKVLAKVLAQMNYGGCVAACGLAGGFTLPTTVMPFILRNVRLQGVDSVMTPPERRA
                     QAWQRLVADLPESFYTQAAKEISLSEAPNFAEAIINNQIQGRTLVKVN"
     gene            110707..111177
                     /gene="accB"
                     /locus_tag="RN951_000231"
                     /gene_synonym="fabE"
     CDS             110707..111177
                     /gene="accB"
                     /locus_tag="RN951_000231"
                     /gene_synonym="fabE"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HDX2525297.1"
                     /translation="MDIRKIKKLIELVEESGISELEISEGEESVRISRAAPAASFPVM
                     QQAYAAPMMQQPAQSNAAAPATVPSMEAPAAAEISGHIVRSPMVGTFYRTPSPDAKAF
                     IEVGQKVNVGDTLCIVEAMKMMNQIEADKSGTVKAILVESGQPVEFDEPLVVIE"
     gene            111188..112537
                     /gene="accC"
                     /locus_tag="RN951_000232"
     CDS             111188..112537
                     /gene="accC"
                     /locus_tag="RN951_000232"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009483995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDX2525298.1"
                     /translation="MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLL
                     ADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIF
                     IGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKA
                     SGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADG
                     QGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFE
                     FLFENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHA
                     VECRINAEDPNTFLPSPGKITRFHAPGGFGVRWESHIYAGYTVPPYYDSMIGKLICYG
                     ENRDVAIARMKNALQELIIDGIKTNVDLQIRIMNDENFQHGGTNIHYLEKKLGLQEK"
     gene            112646..112888
                     /locus_tag="RN951_000233"
     CDS             112646..112888
                     /locus_tag="RN951_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdT family protein"
                     /protein_id="HDX2525299.1"
                     /translation="MDTRFVQAHKEARWALGLTLLYLAVWLVAAYLSGVAPGFTGFPR
                     WFEMACILTPLLFIGLCWAMVKFIYRDIPLEDDDAA"
     gene            112878..114329
                     /gene="panF"
                     /locus_tag="RN951_000234"
     CDS             112878..114329
                     /gene="panF"
                     /locus_tag="RN951_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312157.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/pantothenate symporter"
                     /protein_id="HDX2525300.1"
                     /translation="MQLEVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMG
                     GIVLAMTLTATYISASSFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILA
                     RRYNAVTLNDMLFARYQSRLLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYET
                     GLLIFGISIALYTAFGGFRASVLNDTMQGLVMLIGTVVLLIGVVHAAGGLSNAVQTLQ
                     TIDPQLVTPQGADDILSPAFMTSFWVLVCFGVIGLPHTAVRCISYKDSKAVHRGIIIG
                     TIVVAILMFGMHLAGALGRAVIPDLTVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMS
                     TINAQLLQSSATIIKDLYLNIRPDQMQNETRLKRMSAVITLVLGALLLLAAWKPPEMI
                     IWLNLLAFGGLEAVFLWPLVLGLYWERANAKGALSAMIVGGVLYAVLATLNIQYLGFH
                     PIVPSLLLSLLAFLVGNRFGTSVPQATVLTTDK"
     gene            114341..115222
                     /gene="prmA"
                     /locus_tag="RN951_000235"
     CDS             114341..115222
                     /gene="prmA"
                     /locus_tag="RN951_000235"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HDX2525301.1"
                     /translation="MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPL
                     PGETRLWGDTDVIGLFDAETDMNDVVAILENHPLLGAGFAHKIEQLEDKDWEREWMDN
                     FHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGK
                     TVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQ
                     PEEMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADSFAL
                     DPVVEKEEWCRITGRKN"
     gene            115551..116516
                     /gene="dusB"
                     /locus_tag="RN951_000236"
     CDS             115551..116516
                     /gene="dusB"
                     /locus_tag="RN951_000236"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HDX2525302.1"
                     /translation="MRIGQYQLRNRLIAAPMAGITDRPFRTLCYEMGAGLTVSEMMSS
                     NPQVWESDKSRLRMVHIDEPGIRTVQIAGSDPKEMADAARINVESGAQIIDINMGCPA
                     KKVNRKLAGSALLQYPDVVKSILTEVVNAVDVPVTLKIRTGWAPEHRNCEEIAQLAED
                     CGIQALTIHGRTRACLFNGEAEYDSIRAVKQKVSIPVIANGDITDPLKARAVLDYTGA
                     DALMIGRAAQGRPWIFREIQHYLDTGELLPPLPLAEVKRLLCAHVRELHDFYGPAKGY
                     RIARKHVSWYLQEHAPNDQFRRTFNAIEDASEQLEALEAYFENFA"
     gene            116542..116838
                     /gene="fis"
                     /locus_tag="RN951_000237"
     CDS             116542..116838
                     /gene="fis"
                     /locus_tag="RN951_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001465625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator Fis"
                     /protein_id="HDX2525303.1"
                     /translation="MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNG
                     QDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN"
     gene            116924..117808
                     /gene="yhdJ"
                     /locus_tag="RN951_000238"
     CDS             116924..117808
                     /gene="yhdJ"
                     /locus_tag="RN951_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417728.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
                     /protein_id="HDX2525304.1"
                     /translation="MRTGCEPTRFGNEAKTIIHGDALAELKKIPAESVDLIFADPPYN
                     IGKNFDGLIEAWKEDLFIDWLFEVIAECHRVLKKQGSMYIMNSTENMPFIDLQCRKLF
                     TIKSRIVWSYDSSGVQAKKHYGSMYEPILMMVKDAKNYTFNGDAILVEAKTGSQRALI
                     DYRKNPPQPYNHQKVPGNVWDFPRVRYLMDEYENHPTQKPEALLKRIILASSNPGDIV
                     LDPFAGSFTTGAVAVSSGRKFIGIEINSEYIKMGLRRLDVASHYSAEELAKVKKRKTG
                     NLSKRSRLSEVDPDLIAK"
     gene            117892..118071
                     /locus_tag="RN951_000239"
     CDS             117892..118071
                     /locus_tag="RN951_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2556 family protein"
                     /protein_id="HDX2525305.1"
                     /translation="MIRKYWWLVVFAVFVFLFDTLLMQWIELLATETDKCRNMNSVNP
                     LKLVNCDELNFQDRM"
     gene            complement(118074..118736)
                     /gene="acrS"
                     /locus_tag="RN951_000240"
     CDS             complement(118074..118736)
                     /gene="acrS"
                     /locus_tag="RN951_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor AcrS"
                     /protein_id="HDX2525306.1"
                     /translation="MAKRTKAEALKTRQELIETAIAQFAQHGVSKTTLNDIADAANVT
                     RGAIYWHFENKTQLFNEMWLQQPSLRELIQEHLTAGLEHDPFQQLREKLIVGLQYIAK
                     IPRQQALLKILYHKCEFNDEMLAEGVIREKMGFNPQTLREVLQACQQQGCVANNLDLD
                     VVMIIINGAFSGIVQNWLMNMAGYDLYKQAPALVDNVLRMFMPDENITKLIHQTNELS
                     VM"
BASE COUNT        29247 a        31786 c        29519 g        28246 t
ORIGIN      
        1 attatgtact tgttacaagg ataaggttat atatgaataa agttacaaaa acagctattg
       61 cgggcttact tgcgcttttc gcaggtaatg ccgctgcaac cgatggtgaa atagtttttg
      121 atggcgagat tttaaaatcc gcttgtgaaa tcaatgactc tgataagaaa attgaagttg
      181 ctcttggtca ctataatgcc gaacagtttc gtaatattgg cgagcgtagc ccaaaaattc
      241 cattcactat tcctttagtt aactgcccaa tgactgggtg ggagcacgat aacggcaacg
      301 ttgaagcgtc tttccgtcta tggctggaaa cgcgagataa tggcaccgtc cctaacttcc
      361 ctaatctggc aaaagtaggc tcttttgctg gcatagcggc aacaggtgtg ggtatccgta
      421 ttgacgatgc ggaaagcgga aacattatgc cactgaatgc tatgggcaat gataacacgg
      481 tttatcagat cccggcggaa tccaatggta ttgtcaatgt tgacctcatc gcttactacg
      541 tatcaaccgt agttccatca gaaatcaccc caggggaagc agacgctatc gttaacgtaa
      601 cgctggatta ccgttaatac gttagggcgt tatctgacct gtcagataac gcccttttcc
      661 ttcctctttc tcgttgtatc aggttgaaaa ataactatgt caaaacgaac attcgcggtg
      721 atattaacct tgttgtgtag cttctgtatt ggccaggcgc ttgcaggagg aatcgtttta
      781 cagcgaacgc gagtgatcta tgatgccagc cgcaaagagg ctgcgttacc tgtcgcaaac
      841 aaaggcgcag aaacgcctta tttactgcaa tcatgggtag ataatataga tggtaaaagc
      901 cgtgccccat ttattataac cccaccgcta tttcgtcttg aggctggcga tgactcatca
      961 ctgcgaatta ttaaaacagc tgataacctg cctgaaaata aagagtcgct gttctacatt
     1021 aatgttcgtg ccattcctgc aaagaaaaaa tcagatgatg ttaatgctaa cgagttgacg
     1081 ctggtattta aaacacggat caaaatgttt tatcgccccg cacacctgaa gggacgggta
     1141 aacgatgcgt ggaaatcact ggaatttaaa cgtagtgacc attcactcaa tatatataac
     1201 ccaactgaat attacgtcgt atttgccgga ctggcagtcg ataaaaccga tctcacaagc
     1261 aaaattgaat atatcgcgcc cggagaacat aaacagttac cacttcctgc atctggcgga
     1321 aagaacgtga aatgggctgc gatcaatgat tatggcggca gttccgggac agaaactcgt
     1381 ccactgcaat aacaaatata aaaaacacag gtcatcaggg aatgccacaa cgacaccacc
     1441 agggacataa acgcacaccg aaacagttgg cgctcatcat caaacgttgt ttgccgatgg
     1501 tgctcactgg cagcggcatg ctttgcacta ccgctaacgc cgaagagtat tatttcgacc
     1561 ccattatgct ggaaaccaca aaaagtggta tgcaaacaac cgatctgtcg cgtttttcaa
     1621 aaaaatatgc acaactacca ggaacttatc aggttgatat ctggctgaat aaaaagaagg
     1681 tttcacagaa aaaaattaca tttaccgcca atgcagagca acttctgcag ccacagttta
     1741 cggtagaaca actacgtgag ctgggtatta aggtggatga aatcccggcg ctggctgaaa
     1801 aagatgacga tagcgtgatc aactcgcttg aacaaatcat tcccggtaca gctgctgaat
     1861 ttgatttcaa tcatcagcaa cttaatttga gcattcccca aattgcactg taccgtgatg
     1921 caagaggtta cgtctcccct tctcgttggg acgatggtat accaacgctg tttaccaact
     1981 actcgtttac aggttctgat aaccgttacc gccagggcaa tcgtagccaa cgacagtacc
     2041 tgaatatgca aaatggtgct aattttggcc cctggcgatt acgcaactat tccacatgga
     2101 cacgcaacga tcagacatca agctggaata ccatcagtag ttatttacaa cgtgatatca
     2161 aggcgttgaa gtctcagttg cttctgggag aaagcgccac cagcggcagt attttttcca
     2221 gctacacctt tactggcgtg caactcgctt ccgacgataa tatgttgcca aacagccagc
     2281 gcggatttgc cccaacggta cgcggtatcg caaacagtag tgcaatcgtg actatcaggc
     2341 aaaatggtta tgtgatctat caaagcaacg tgtcagcggg tgcctttgaa attaacgatc
     2401 tctacccctc ttccaacagc ggcgatttag aagtcacgat tgaagaaagt gacggtacac
     2461 aacgtcgctt tatccagcct tattcttcat tacccatgat gcagcgacct gggcatctaa
     2521 agtatagcgc gaccgctgga cgctatcgcg ctgatgcaaa cagtgatagc aaggaacccg
     2581 aatttgctga agccacggca atatatggtt tgaataatac ttttacgctg tatggcggcc
     2641 tgctcggttc tgaagattat tatgcgctgg ggatcggtat cggcggcaca cttggcgcac
     2701 tgggcgcgtt gtcgatggat atcaacagag ctgacaccca attcgataac cagcactctt
     2761 ttcatggcta tcaatggcgt acgcagtaca tcaaagatat cccggaaacc aacaccaata
     2821 tcgctgtcag ctactatcgc tataccaacg atggctattt tagttttaat gaagccaata
     2881 cccgcaattg ggactataac agtcgccaaa aaagtgaaat tcaattcaac atcagccaga
     2941 caatatttga tggggtaagt ctgtatgcct ccggttcgca gcaagactat tggggcaata
     3001 acgataaaaa caggaatatc tctgttgggg tttccggcca gcaatgggga gttggttaca
     3061 gcctgaatta tcaatacagc cgctacactg atcaaaataa tgaccgcgca ctctctttga
     3121 atctcagtat tccgttagaa cgctggttac cgcgtagccg ggtttcctat cagatgacca
     3181 gccagaaaga tcgcccaacc caacatgaaa tgcgtcttga tggctcactg ctggatgatg
     3241 gtcgcctgag ctatagcctg gaacaaagtc tggatgacga taacaaccat aacagtagcc
     3301 tgaacgccag ttaccgttca ccttatggca ccttcagtgc cggatacagc tacggtaatg
     3361 acagcagcca atacaattac ggcgttaccg gcggcgtggt tatccatcct catggcgtga
     3421 cgctctcgca atatctgggc aacgcttttg cgcttatcga tgctaacgga gcatctggcg
     3481 tgaggataca aaactatccg gggattgcta ccgatccttt tggctatgca gtggttcctt
     3541 atctcacaac ttatcaggaa aaccgtctct cggtagatac tacgcagctg cccgataacg
     3601 tcgatcttga acaaacaaca cagtttgtgg tgcccaacag aggtgcaatg gtagcggcgc
     3661 gtttcaacgc caatatcggt tatcgcgtac ttgttacagt cagcgatcgc aacggtaaac
     3721 cgttgccctt tggcgctctt gccagcaacg atgatacggg gcaacaaagt atcgtcgatg
     3781 agggcggcat actatatctc tctgggatat cgagtaaatc acaaagctgg actgtacgct
     3841 ggggaaatca ggcagatcaa caatgtcagt ttgctttcag tacaccggat tcagaaccta
     3901 caacctctgt attacaaggc acagcgcagt gccattaagg ataaaaaaat gaaaagagcg
     3961 cctcttataa caggtctttt gttgatatcc acatcctgcg cttatgcctc ctcaggaggg
     4021 tgtggagccg acagcactag cggtgcgaca aattacagca gtgtggttga tgatgttacg
     4081 gtgaaccaga cagataacgt gacaggacgg gagtttacct ctgcaacgct aagtagcact
     4141 aactggcaat acgcctgttc ctgctctgcg ggtaaggcag ttaaacttgt ctatatggtc
     4201 agccccgtac ttaccaccac tggacatcag acaggatatt acaaactcaa tgacagcctg
     4261 gatattaaaa ccacattaca ggcaaacgac attccaggac tcacaaccga ccaggttgtc
     4321 tctgttaaca cccgattcac acagataaaa aacaacacgg tatattctgc tgcaacccaa
     4381 acgggtgttt gccagggtga tacgtctcgt tatggacccg ttaatattgg tgcgaacacc
     4441 acctttaccc tgtatgtcac caagccattt ctcggctcga tgaccattcc gaaaacggat
     4501 attgccgtca ttaaaggcgc gtgggtcgat ggaatgggaa gcccgtctac aggtgacttc
     4561 catgatttag tcaagttatc gattcaggga aatctcaccg ccccacagtc gtgcaaaatt
     4621 aatcagggcg atgttattaa ggttaatttt ggattcatca atggtcagaa gtttaccacc
     4681 cgcaatgcca tgccagacgg ttttactcca gtagactttg atatcactta tgactgtggt
     4741 gatacttcaa agattaaaaa ctcgttgcaa atgcgcatcg acggtacaac tggggtagta
     4801 gaccagtaca acctggtcgc caggcgaaga agttcagaca atgtgcccga tgtcggtatt
     4861 cgtattgaaa atctcggcgg cggagttgca aatattcctt ttcagaacgg tatccttccc
     4921 gttgatcctt ccgggcatgg caccgtcaat atgcgcgcct ggccagttaa tctggtcggt
     4981 ggtgagctgg aaacaggaaa atttcagggc acagccacca ttaccgtcat cgtgcggtaa
     5041 aagaagacgt tgcgttttga ttaacgcaac gcttcggcac tgttacccct gctgctccag
     5101 cgcatactta tacagcgcat ttttcttcac gccgtgaatt tctgcggcca gcgccgccgc
     5161 ttttttcagc ggcagttctg cctgtagcag cgccagcgtg cgcagggcat cggcgggtaa
     5221 gtcttcttcc tgtgctttat gaccttcgac aatcagcacc atttcgcctt tgcgacggtt
     5281 ttcatcttcc tttacccacg ccagcagctc gccaacgggc gcgccgtgaa tggtttccca
     5341 ggttttggtc agctcacgcg ccagaaccac gtagcgggat tcgcctaata ccgcaacgat
     5401 atcttccagg ctatctaaca gacggtgggt agattcataa aaaatcagcg tgcgcggctc
     5461 cgcttcaatg gcttttagcg catcacggcg gccttttgat ttggcaggta aaaagccttc
     5521 gtaacagaaa cggtcagagg gtaaacccgc tgcgcttaac gcagtgatag cagcacacgg
     5581 cccgggtagc ggcaccacgc ggatccccgc ttcacggcag gtacgcacca gatggtagcc
     5641 aggatcgtta attagcggcg ttccggcatc ggaaaccagc gcaatgtttt gcccctcttg
     5701 cagcttcgcc agcagcgttt cagctttttg ttgttcgtta tggtcgtgca gcgcaaacaa
     5761 ccgggcatta atcccaaaat gttgcagcaa taaaccggtg tgacgagtat cctcggcggc
     5821 aatcagatca acggcctgta atacctctaa cgcacgctgg gtgatatccg ccagattgcc
     5881 gattggcgtc ggtacaatgt aaagctggcc ctgagaatta tccgccgatt ggtgttgttt
     5941 cattgtgtcg tccgtattgc cgatttaata ttgagcattg cgtaaaaaaa atatcactgg
     6001 atacattatg gtaccctcaa cattttctcg tttgaaagcc gcgcgttgtc tgcctgttgt
     6061 tctggcagcc ctgattttcg ccggttgtgg cacccatact cccgatcagt ccactgctta
     6121 tatgcagggc acggcgcagg ctgattctgc cttttatctt cagcagatgc agcaaagctc
     6181 tgatgatacc aggatcaact ggcaattact cgccattcgt gcactggtga aagaaggtaa
     6241 aaccgggcag gcggttgagt tgtttaacca actaccgcaa gaactgaacg atgctcagcg
     6301 tcgcgagaaa acactgctgg cggtagagat taaactggcg cagaaagatt ttgctggcgc
     6361 gcaaaacttg ctggcgaaaa tcacacctgc cgatttagaa caaaaccagc aagcgcgtta
     6421 ctggcaggca aaaatcgatg ccagccaggg gcgtccttcc attgatttac tgcgcgcgtt
     6481 aattgctcag gaaccgctgc ttggcgcgaa agaaaaacag cagaatattg atgccacctg
     6541 gcaggcgctc tcctccatga ctcaggaaca ggcgaatacg ctggtgatca acgccgacga
     6601 aaatattctg caaggctggc tggatctgca gcgcgtctgg tttgataacc gtaacgatcc
     6661 cgacatgatg aaagccggga tcgccgactg gcagaaacgt tatccgaaca atccgggcgc
     6721 gaaaatgctg ccaacgcagt tggttaacgt aaaagcgttt aaaccagcct cgaccaacaa
     6781 aatcgccctg ctgttgccac tgaatggcca ggcagcggta tttggtcgca ctattcagca
     6841 aggctttgaa gcggcgaaaa atatcggcac tcagccagtg gcagctcagg tagctgccgc
     6901 acctgccgca gacgtagctg aacaacctca gccgcaaacc gtggatggcg ttgccagccc
     6961 ggcacaagcc tcggttagcg atctgaccgg tgaacagcct gcagcccagc cggtgcctgt
     7021 aagcgccccg gcgacaagca ccgcagcggt aagcgcaccc gcaaatccat ccgcagagct
     7081 gaaaatctac gatacctcat cacaaccact tagccagatc ttaagccagg ttcagcagga
     7141 tggcgcgagt attgtggtcg gtccgttgct gaaaaataac gttgaagagt tgctgaagag
     7201 caacactccg ctgaacgtac tggcactgaa ccagccggag aatatcgaaa atcgcgtcaa
     7261 tatttgttac ttcgcgcttt caccggaaga cgaagcgcgc gatgcagcgc gtcatattcg
     7321 tgaccagggt aaacaagcgc cgctggtgct gatcccacgc agttcattgg gcgatcgcgt
     7381 agccaatgcg tttgcgcaag agtggcagaa actgggcggc ggcaccgttc tgcaacaaaa
     7441 atttggttcc accagcgaat tacgcgcggg tgttaacggc ggttctggta ttgctttaac
     7501 gggtagcccg attactctca gagcgacaac cgactccggc atgacgacca acaatccaac
     7561 gctgcaaacc acgccaaccg atgaccagtt caccaataat ggcggtcgtg tcgatgcggt
     7621 gtacattgtg gcaacgccgg gtgaaatcgc ttttatcaaa ccgatgatcg ccatgcgtaa
     7681 cggtagccag agcggtgcaa cgctgtacgc cagctcccgc agtgcgcaag ggaccgctgg
     7741 cccggatttc cgactggaga tggaaggctt gcagtacagc gaaatcccga tgctggcagg
     7801 cggtaatcta ccgttaatgc agcaggcact cagcgcggtg aataacgatt attcactggc
     7861 tcgcatgtat gcgatgggcg tcgatgcctg gtcgctggca aatcatttct cacaaatgcg
     7921 ccaggttcag ggttttgaaa tcaacggtaa taccggaagc ctgacggcta acccggattg
     7981 cgtgattaac aggaacttat catggctaca gtaccaacaa ggtcaggtag tccccgccag
     8041 ttaaccacca aacagaccgg cgatgcgtgg gaagtacaag cgcgtcgctg gctggaaggc
     8101 aaaggactgc gatttgtcgc cgctaacgtg aacgagcgtg gcggcgagat cgatctgata
     8161 atgcgtgaag gccggaccac cgtttttgtc gaggtacgct atcgccgctc tgcgctttat
     8221 ggcggcgcgg cagccagtgt gacccgcagc aaacaacaca aattattaca gactgcccgc
     8281 ttgtggctcg cgcgtcataa tgggagtttt gatactgtgg attgccggtt cgatgtggta
     8341 gccttcaccg ggaatgaggt tgagtggatt aaggatgcct ttaatgacca ctcataatta
     8401 aggtttaagg attagcgtgc aagaaagaat taaagcttgc ttcactgaaa gcattcaaac
     8461 tcaaattgcg gcggcagagg cgcttccgga tgccatctcc cgtgcagcca tgacgctggt
     8521 tcagtctctg ctcaatggca acaaaatcct ctgttgtggt aatggaactt ccgctgccaa
     8581 tgcacagcat tttgctgcca gcatgatcaa ccgtttcgaa acggagcggc ccagcttacc
     8641 tgccattgca ctaaatactg ataatgttgt cttaacggcg attgccaacg atcgcttaca
     8701 tgatgaagtg tatgcaaaac aggtgcgggc gctgggtcat gcgggagatg tattgttagc
     8761 catttccacc cgtggcaaca gccgcgatat tgttaaagca gttgaagccg ccgttacgcg
     8821 tgatatgacc attgtggcat tgaccggata tgacggcggc gagcttgcag gtttgttagg
     8881 gccacaggat gtggagatcc gcattccttc gcatcgtagt gctcgcattc aggaaatgca
     8941 tatgctgacg gtaaattgcc tgtgcgatct gatcgataac acgcttttcc ctcaccagga
     9001 tgattaagga gaatacatga aggcattatc gccaatcgca gtccttattt ccgcgctgct
     9061 gttgcaaggt tgtgttgccg ctgccgtagt gggtaccgct gctgtgggta ccaaagccgc
     9121 aactgaccca cgcagtgtcg gcacccaggt ggacgatggt accctggaag tgcgcgtgaa
     9181 cagcgcattg tcgaaagacg aacagattaa gaaagaaacc cgtattaatg tcacggcgta
     9241 tcagggcaaa gtgctgctgg ttgggcagtc accaaacgct gaactttcgg ctcgcgccaa
     9301 acagattgct atgggcgtag acggtgccaa cgaagtgtat aacgagattc gtcagggcca
     9361 gccgattggt ctgggcgaag catctaacga tacgtggatc accaccaaag tgcgttcgca
     9421 gctcttaacc agcgacctgg tgaaatcgtc caacgtgaaa gtgaccaccg aaaacggtga
     9481 agtgttcctg atggggctgg tgactgaacg tgaagcgaaa gcggcggcag atattgccag
     9541 ccgggtgagc ggcgtaaagc gggtaaccac agcgtttacg tttattaaat agcagcccct
     9601 tgtaatgcct gatgcgacgc ttgccgcgtc ttatcaggca tacaacgatg caaaccgtag
     9661 atcggataag gcgtttacgc cgcatccgac atgttttccc tcaaatcaga acaacagcgc
     9721 cagcccgccg acaatcacac cagacactgc caccatcgcc cctgtcagcc ataaggcttt
     9781 cgccgggaac gctttgcgca gcataatcag tgacggcaaa ctcactgccg ggagcgtcat
     9841 caacaatgcc agcgccggag cggttcccat acctgccagc atcatcgttt gtacaatcgg
     9901 aatttctgct gccgtgggaa tgacaaacaa gcatcctgcc accgccatcg ccaccaccca
     9961 catcaggctg ttatcgacag caccatcggc atgggggaat aaccagacgc gagcggcacc
    10021 caacaccagt actgcaagga tgtaaaccgg gatcgtactc cagaaaagcg tccatagcgc
    10081 cctgccccag cggctaaaaa aaccgccctg tgcttccggt atgtcaattt cgaccggtgc
    10141 ctgcgtttgc ggtgtttcac gcacccattt ttgcaccagc gtcgcaatca gcaacaccat
    10201 caccagcccg gccaccagac gaatcaccgc aaaaccccag ccgaggacaa accccataaa
    10261 caccagcgtc gccgggttta acaccggatt gcccatccag aatgccagcg caccgcccat
    10321 cgacacctgt tggcgacgca ttcccgccgc gaccggagcc gcacagcagg tacacatcat
    10381 gcccggcagc gaaaacagcg ttcccagcag cgtgccgcga aagcgcgatt gcccaagcgt
    10441 acgcaacaac cagtcacgcg ggatcagcac ctgaatcaac gaaccgagga tcacccccag
    10501 caccgccgct ttccataccg cgaggaaata gatcatcgcg taatccaacg ccgcctgcca
    10561 tgggttagca tccgcctgcg caaggataga tttaccgata ctgtgggttt cggcagcagt
    10621 aaacgctttg ccgtagtaag gttcccattt cacataccag agaccggcaa tgacaacgag
    10681 aaagaaaagc gcgggtttcc accactgaat gggcgttgcc gcctgagatg aagactgacc
    10741 agtcatagca ttccccagga ataagttatg ataattgagc gcgtgaatat tacgctcact
    10801 atcaattctt gggaataatt attcagctct tttgcgtaat tctgaagagc ttaaaatcgt
    10861 cacgccttca tgctcaggcc acatcgactc tgccagcatg acccgcgcca cgtctctcgc
    10921 atcaatggat ttccagttac ctggtaacaa acggcacagc ggcgcaaaaa gcgtttcgtt
    10981 catccgctgt ttgctacgat cgcccagtaa catcgacggg cgagcaatgg tcaatttcgg
    11041 ccagttctgg gcgattaatg cttcttccat ctcccctttg acgcggttat agaaaaacgg
    11101 cgagtgggca ttggcaccca tcgcactgac taccaacata tgctgcgcgc ccagtcgccg
    11161 cccggttaat gcggtatcca ctaccagcgt gtaatcggca tgaataaacg cctctttgct
    11221 ccccgcttct cgccgcgtgg tgccgagaca acaaaacaca atgtcgatgg gatcggtgac
    11281 ctgcgccaac gcgtcactca gttgcggatc atggggatta aacaccccgg gcatatcgcc
    11341 caacggacgt cgcgtcggcg cagcaatggc gttaactttc ggttcgttaa tcaacatccg
    11401 cagcaggtga ccgcccacca gccccgttgc gcctgtaatc agtacctgac tcatcttcgc
    11461 tcctttacag aattgtctgc cttgcgctcc acggctcatg caccaggctt aatagaccat
    11521 gaggtaatta tccccgattg tgggaaattc gcctcatcca atgcaacaac gcggaggaag
    11581 catgagtaag aaaattgccg ttttaatcac tgatgaattt gaggattcag aatttacttc
    11641 acccgcagac gagttccgta aagccggaca cgaagtgatt accattgaaa aacaagcggg
    11701 taaaacggtg aaaggcaaaa aaggagaagc cagcgtgacc atcgataaat ccatcgatga
    11761 agtgacgcct gcggagtttg atgccctgct gctaccgggc ggccattcac cggattatct
    11821 gcgtggggac aaccgttttg tcacctttac ccgtgatttt gtgaatagtg gcaaaccggt
    11881 gtttgccatc tgtcacggcc cgcagttgct gatcagcgcc gatgtgattc gggggcgcaa
    11941 actgaccgca gttaaaccga tcattattga tgttaaaaat gcgggcgcgg aattttacga
    12001 tcaggaagtc gtggttgata aagatcagct ggttaccagc cggacaccgg acgatctgcc
    12061 agcgtttaac cgcgaggcgt tacgcctgct cggtgcctga gtcgcgtagc caaatcattt
    12121 ttttaccaaa gcccagcgtg ttgtcggtga atttgatttc atcgagccgg atttcccaca
    12181 ccggggccga cagcattctg gcaaccggaa agcgacgatt gtacgccttg cgcgcgaggt
    12241 cgctttcctc accttccagc ctgcggatct cacctttaaa ctgcacaccg cgaattaacg
    12301 ctaccgtttt cggctgaccg tttaccgttc cggcaactgc cgcctgcggc ccgctcatct
    12361 gcgcgtggcg cgttttttct tccgtcaaaa tgtagaaggc gactttctgc gcatcaaaaa
    12421 gataaaaggc attagcgcac cagagttccc cttcctgctg cacacaccag gtgacaacat
    12481 gttgttttgc cagccaacgg ctgatggcga tgagtgtttc cattgctgtt ctcttttata
    12541 ctgtgggcct gaccttaaca tgcgatgcag acgatgacac cctggtttct ttacttgatc
    12601 cgtaccgccg acaataagct ttataccggg atcaccacgg atgtcgaacg ccgctatcag
    12661 cagcaccaaa gcggcaaagg ggcgaaagca ctgcgcggga aaggagaact gacgctggcg
    12721 ttttctgctc cagtgggcga tcgttcgctg gcgttacggg cggaatatcg cgttaagcaa
    12781 ctgaccaaac ggcaaaaaga gcgtctggta gcggaaggcg cagggtttgc agagctgtta
    12841 agcagtctgc aaaccccgga gattaaaagc gattgaaatg ctcgtgatac tcaaccaggc
    12901 cggtaacgcc attcagcgcg tcatccgcta aacgatgtac ctggaaggcg ctttcagtgc
    12961 ccggccagcg gcaacgcaga tcgtgatgcg ccgccagttc aaagccgaaa cgactgtaca
    13021 gcgccggatc gcccagcgtc accactgcgg catagccgaa ctcattaagc gaatcgagtc
    13081 cttcatagac cagttggcgt gccagcccct gtccacggta tttttcatca accgccaacg
    13141 gtgccatgcc gacccattgc aggtcttcgc cctgcacatc aaccggacta aatgccacat
    13201 agccaatgac ctgaccttcg tcatctgtcg ccaccagccc cagcgtcaga aagccatctt
    13261 cacgcagatc gtgaaccagc ttcgcttccg catcactttc gaatgagcga cgcagcaggg
    13321 catcaatacc cggcgcatca atgggaattt ctactcgaat tagcatggtt cacctaccga
    13381 tgtctgtttg gtttcaggcg cggttttcat tcccgcctca acaaaatccg ccagttgcag
    13441 cagcatcatg cgtaaggctt tcggcatttg ctccagttca atggcgtcca tcaggttttt
    13501 cacatacagc cccagctccg tatcgccttc aatcaccagc cgacgctgga agaagagcgt
    13561 atccggatct tgtttacgcg ccgcaatcat cagcagatcg ctggcgtcgg cactaaaact
    13621 cacatcagct tgcgcgttct ggctgaccac cagtttgcca ttcaccaccg aggtaaacca
    13681 ttgcaggtca atatcacgca catgaatact taaccagcgg ccttcaagaa actccagctc
    13741 accatcatcc agcgcctgac ggaattgcca gcttaagacc tgctcaagaa cctggcgttt
    13801 tagcgcaaat ggcgtcagtt ttaccggtac actcaacaga gatggcccca aatgcacaat
    13861 acgggaacgc agtttatcca acacgagttt tactccctgt ttcaacaatc atcctatttt
    13921 gccatatcag aaaaataaca tagcggtata aatcaacaat tccatatgaa attgctgcta
    13981 ccaccaatac aactttaact gccttaaatc aaaaattgtc gcagcaaggt taactaaaat
    14041 cccagttcgt taacattttt gcgttttgat agcgcaacct tcaggaaaaa ttatggagct
    14101 gctctgccct gccggaaatc tcccggcgct taaggcggcc atcgaaaacg gcgcagatgc
    14161 tgtttatatc gggctaaaag atgataccaa tgcccgtcac ttcgccggcc ttaactttac
    14221 cgagaaaaaa ttgcaggaag cggtgagttt tgtccatcaa catcgccgca aacttcacat
    14281 cgcgattaac acttttgcgc atccggacgg ttacgcccgt tggcagcgcg ccgtggatat
    14341 ggcggcgcag ctgggtgccg acgcgctgat cctcgccgac ctcgccatgc tggaatacgc
    14401 cgccgagcgt tatccgcata ttgagcgcca cgtatcggtg caggcttcgg cgaccaatga
    14461 agaggcgatt aacttttatc atcgccattt tgacgttgcc cgcgtggtgc tgccgcgcgt
    14521 gttgtcgatt catcaggtga aacaactggc acgggtcaca cctgtaccac tggaagtgtt
    14581 tgctttcggc agcctgtgca ttatgtcgga aggtcgttgc tatctgtcgt cgtatctgac
    14641 gggtgagtcg cccaacaccg taggcgcgtg ttctccggcc cgtttcgtgc gctggcaaca
    14701 aacgccgcag gggctggaat cccgcctgaa cgaagtgctg atcgaccgtt atcaggacgg
    14761 cgaaaacgca ggttatccga cgctatgtaa agggcgttat ctggtggacg gcgagcgcta
    14821 tcacgcgctg gaagaaccaa ccagtctcaa taccctggaa ctgctgccgg agttaatggc
    14881 ggcgaatatt gcttcggtga aaattgaagg ccgccagcgt agcccggcgt atgtcagcca
    14941 ggtggcgaaa gtctggcgtc aggctatcga ccgttgtaag gccgatccgc aaaactttgt
    15001 accgcaaagc gcgtggatgg agacgctcgg gtcgatgtcc gaaggcacgc aaaccactct
    15061 tggcgcatat caccgtaaat ggcagtgaga aaagcaatga aatattcctt agggccagtg
    15121 ctgtggtact ggccaaaaga gacgctggaa gaattttatc agcaggccgc caccagcagc
    15181 gccgacgtga tttatcttgg tgaagcggta tgcagcaagc gtcgggcaac caaagttggc
    15241 gactggctgg agatggcaaa atcgctcgcc gggagtggta agcagattgt gctctccacg
    15301 ctggcgctgg tgcaggcatc atctgaactg ggcgaactga aacgctatgt tgagaacggt
    15361 gagtttctga ttgaagccag cgatctcggc gtggtgaata tgtgcgctga acgcaaactg
    15421 ccgttcgtcg ccgggcacgc gctgaactgc tacaacgcgg tgacactgaa aatattgctc
    15481 aaacagggca tgatgcgctg gtgtatgcca gtggagcttt cccgcgactg gctggtgaat
    15541 ctgcttaatc agtgcgatga gctgggcatt cgtaaccagt ttgaagtgga agtcctgagc
    15601 tacggtcatc tgccgctggc ctactccgcc cgctgcttta ccgcgcgttc ggaagaccgc
    15661 ccgaaagatg agtgtgaaac ctgctgcatt aagtatccga acgggcgcaa cgtgctgtcg
    15721 caggaaaacc aacaagtgtt tgtactcaat ggcattcaga ccatgagcgg ctacgtttac
    15781 aacctcggta acgagctggc atccatgcag ggcctggttg atgtggtccg cctgtcaccg
    15841 cagggtactg acactttcgc gatgctcgac gccttccgcg ctaatgaaaa tggcgctgca
    15901 ccactgccgt tgacggcgaa cagcgactgt aacggctact ggcggcggct ggcaggactg
    15961 gagctgcaag cctaagtaaa tagctcactt tgttaacaac tttaactact ctttaatgca
    16021 gtattaaaga ttaatcggta acaaagtgag ctgttatgac tgataaaacc attgcgtttt
    16081 cgctactcga tctggccccc attcccgaag gttcttcagc gcgagaagca ttctcccact
    16141 ctctcgatct cgcccgtctg gctgaaaagc gcggctatca tcgctactgg ctggcagaac
    16201 accacaatat gactggcatt gccagtgctg ccacgtcggt attgatcggc tatctggcgg
    16261 cgaataccac cacgctgcat ctggggtctg gcggcgtgat gttgcctaac cactcaccgt
    16321 tggtcattgc agaacagttc ggcacgctta atacactcta tccggggcga atcgatttgg
    16381 ggctgggtcg tgctccgggt agtgaccaac ggacaatgat ggcgctacgt cgtcatatga
    16441 gcggcgatat tgataatttc ccccgcgatg tggcggagct ggtggactgg tttgacgccc
    16501 gcgatcccaa tccgcatgtg cgcccggtac caggctatgg cgagaaaatc cccgtgtggt
    16561 tgttaggctc cagcctttac agcgcgcaac tggcggcgca gcttggtctg ccgtttgcgt
    16621 ttgcctcaca cttcgcgccg gatatgctgt tccaggcgct gcatctttat cgcagcaact
    16681 tcaaaccgtc agcacggctg gaaaaaccat acgcgatggt gtgcatcaat attatcgccg
    16741 ccgacagcaa ccgcgacgct gaatttctgt ttacctcaat gcagcaagcc tttgtgaagc
    16801 tgcgccgtgg cgaaaccggg caactgccgc cgccgattca aaatatggat cagttctggt
    16861 caccgtctga gcagtatggc gtgcagcagg cgctgagtat gtcgttggta ggtgataaag
    16921 cgaaagtgcg tcatggcttg cagtcgatcc tgcgcgaaac cgacgccgat gagattatgg
    16981 tcaacgggca gattttcgac caccaggcgc ggctgcattc gtttgagctg gcgatggatg
    17041 ttaaggaaga gttgttggga tagtgtgtct taacgcggga agccttatcc gagctggcaa
    17101 cgctgtccta catagacctg ataagcgaag cgcatcaggc attgtgtagg cagcagaaat
    17161 gtcggataag gcaccgctga ttactgatac accggcagta aattaaagct cgataaaata
    17221 tgcaccagtg cgttgccgac gccaaacacc agaatcagcg caatcatcgg cttgccaccc
    17281 cagacgcgga atttcgggct gccaaagcgt ttacgcgatg cacgggctaa cagcgccgga
    17341 acaattgccg cccagatggt agccgctaaa ccagcataac caatggcgta caggaatccg
    17401 ttcgggaaca acagcccccc cacaactggc ggggcaaagg tcagcaatgc cgttttcaag
    17461 cggcccacag ccgagtcgtc gaaaccaaac agatctgcca gatagtcaaa caaacccagc
    17521 gttacgccga ggaacgaact cgctaccgca aagtttgaga acacgaccag cagcagatcc
    17581 agactacggc tgttcagtac gccgcttaac gcctgtacca gcacatcaat attaccgccc
    17641 ttctctgcaa taccgataaa ctccggacgc gggatgttac ccatcgtcgc cagcaaccag
    17701 atggtataca gcgccagcgc catcagcgta ccgtacacca gacatttcac gatggttttc
    17761 ggatctttgc cgtaatactt catcaggctt ggcacgttac cgtgataacc aaacgatgcc
    17821 agacagaacg gcagggtcat caacagatac ggtgcataag acgcattgct ttcggcgacg
    17881 ttgaacaatg tcgcaggctg cacatgcccc agcaggctac caaaggtgag gaagaaggta
    17941 atgactttcg cccccagcac aatcgctgtc atgcgactga cggctttagt gctcaaccac
    18001 accacaaacg ctaccagcaa tgcaaaacca aaacccgccg cccgtgccgg gacgtttagt
    18061 gacatctctg cgaaggtgtg atgcagaatc gaaccactgg cagaaatata ggcataggtc
    18121 aggatataga gcacaaaggc aatggaaatg ccgttgacca cgttccagcc tttgcccagc
    18181 aaatctttgg tgatggtgtc aaaactcgaa ccgattctgt aattcaggtt agcttccaga
    18241 atcatcaagc cggaatgcag catacagaac caggtaaaga tcagcgccgc cattgaccag
    18301 aaaaaccacg ccccggacat gaccactggc agagaaaaca tccctgcgcc aataatggtg
    18361 ccgccgataa tcaccacgcc gccaagcagc gacggtgacg tttgggtggt ggttagtgtt
    18421 gccatgaggg cttctctcca gtgaaaaata gtgcgactgc gttgttatgc attgcactgt
    18481 accagtacac gagtacaaaa gacagaaaaa aagccccgat ggtaaaaatc ggggctgtat
    18541 atattatttt acagattgtg ttcgctgttc agcgatgatt acgcatcacc accgaaacga
    18601 cgacgaccgg tagaatcatc acgacgcgga gcgcggcctt cacgacgttc gccgctaaaa
    18661 cgacgaccat caccacggcc accttcacgg cgttcaccgc tgaagttacg accgccttca
    18721 cgacgttcgc caccgaaacc acgaccaccg ccacgacgct caccgccagt atgcggctgt
    18781 gcatcgccca gtaactgcat gttcatcggc ttgttgagaa tgcgagtgcg cgtaaagtgt
    18841 tgcagcactt cacccggcat acctttcggc agttcgatgg tggagtgaga agcaaacagc
    18901 ttgatgttac caatgtaacg gctgctgatg tcgccttcgt tagcaatcgc accaacgata
    18961 tgacgaactt caacaccatc atcgcggccc acttcaatgc ggtacagctg catatcgcca
    19021 acatcacgac gttcacgacg cggacgatct tcacggtcac cacgcgggcc acggtcgtta
    19081 cgatcgcgcg gaccacggtc atcacggtca cggaattcac gtttcggacg catcggcgca
    19141 tctggcggta cgatcagagt acgttcaccc tgtgccattt tcagcagtgc cgcagccaga
    19201 gtttcgagat ccagctcttc accttcagca gtcggctgaa ttttgctcag cagtgcgcgg
    19261 tattgatcca gatcgctgct ttccagctgc tgctgtactt tagcggcgaa tttttccaga
    19321 cggcgtttgc ctagcagttc tgcgttcggc agttctactt ccggaatagt cagcttcata
    19381 gtacgttcaa tgttgcgcag cagacgacgc tcgcggttct caacgaacag cagcgcgcgg
    19441 ccagcacgac ccgcacgacc ggtacgaccg atacggtgaa cgtaagactc agaatccatc
    19501 gggatatcgt agttaactac caggctgata cgctcaacgt ccaggccacg ggctgcaacg
    19561 tcggtcgcaa tcaggatgtc cagacgacca tctttcaggc gttccagtgt ctgttcacgc
    19621 agcgcctggt tcatgtcacc gttcagcgcg gcgctgttgt agccgttacg ctcaagagct
    19681 tcagccactt ccagagtcgc gtttttggta cgaacgaaga taatcgccgc atcaaaatct
    19741 tccgcttcca ggaaacgtac cagtgcttcg tttttgcgca taccccagac agtccagtag
    19801 ctctggctga tgtcaggacg ggtagtcacg ctggactgaa tgcgcacttc ctgcggctct
    19861 ttcataaagc ggcgggtaat gcgacgaatc gcttccggca tggttgcaga gaacagagcg
    19921 gtctgatgac cttccgggat ctgcgccata atggtttcaa cgtcttcgat gaagcccatg
    19981 cgcagcattt cgtcagcttc atccagaacc agaccgctca gtttagagag gtccagagtg
    20041 ccacgtttca ggtggtccag cagacggccc ggagtaccga caacgatctg cggcccctga
    20101 cgcagggcgc gtaattgcac gtcataacgc tggccgccgt acagagcaac cacatttacg
    20161 ccgcgcatgt gtttagagaa atccgtcatt gcttcagcaa cctgtaccgc cagttcgcgg
    20221 gtcggtgcca gcaccagaat ctgtggtgct ttcagctcag gatcaagatt ctgcaacaga
    20281 ggtaaagaga atgctgcagt ttttccgctc cccgtctggg ccatacccag aacgtcgcgg
    20341 ccattcagca gatgtggaat acactctgcc tgaattggag atggtttttc gtaacccaga
    20401 tcgttaaggg cttcaaggat aggagccttc aggcccagat ctgcaaaagt ggtttcgaat
    20461 tcagccatgt agtacgtgtg cctcaaaatt aatggcggcc agtctacata actcatcatg
    20521 aaattgatca gcaattttca ttgaaaagtg tgaaccggct caaagtaggt gtattaacga
    20581 acaacaacgc cctcacccgt taaggtgatg gcaatcaaaa aagattacgg gctgatgtgt
    20641 acgtcagcta ttgctggtcc gattctgcca ggtcatcttg gtcctggccc aggagcgata
    20701 attccaacaa tgcgtatcgg tgctcaacaa agttatgaac gttgttggca accgccagtt
    20761 tgaacagtgc cgtggcgctg tccaaatccc ccagacttag gtagtactta cctaaataga
    20821 agttggtttc actgagatgc tcagcgagcg aggtgttatc cgttgcgtcc gccttgagcc
    20881 tttccattaa cgtttgttcg ctaatgttgc ccaggtagaa ctcgacaatg ttccatcccc
    20941 actgttcctt atccgatttt tcgaagtgct gtttcaacac ttctttagcc tgcttctcat
    21001 cgagcttctg ctcggcgaga taaagccaca gactacggaa aggatcattg ggatcgtctt
    21061 gataaaacgc cagcagatca tcttgcgcta acttgtcacg accgccgtaa tataatgcga
    21121 tcccgcgatt caagtgcgcg tagttgtaag ttggatcaag ctcaagtaca gaatcaaacg
    21181 cttcataggc agcatcaaaa ttgcctgcct gcgttaaata tatgcctaag taattgaata
    21241 cttcaggcat atccggtcgg attgccagcg cttgcgaaaa atcgttacgc gctaatgccc
    21301 tcagaccgag actatcatac aacactccgc gctcatataa aagctgtgcg cgttcgtcat
    21361 cggttaaagc ccgactggca aggatttgtt ccatacgtgc cagaatcact tcctgctgta
    21421 aagtcggttg caatggtacc gcgaggactt cacttttacg ccaggaagta ttactgcatc
    21481 ctgcaagcgt aagtgctgtc gcaacgaaac accagcgcaa aaaaggcttc atttcccact
    21541 cccgaagacc acggttgaat gaacgtcctg ttcccggttg ctaacaaggc gtcctgcccg
    21601 gttaaaagcc ccccgccgca gcggagggca aatggcaacc ttactcgccc tgttcagcag
    21661 ccggagcttc cggtgctgca gcaggttgag actgctcagt cgcttcttta atgctcagac
    21721 ggatacggcc ctggcgatca acttccagaa ctttcaccgg tacttcctga cccatctgca
    21781 ggtaatcggt cactttctca acgcgtttgt cagcgatttg agagatgtgg accagacctt
    21841 ctttaccgcc gccgatggca acaaatgcgc caaagtcaac gatacgggtc actttaccag
    21901 tgtagacgcg gcccacttcg atttctgcag tgatctcttc gatacgacga atagcatgtt
    21961 tcgctttctc gccgtcggtc gctgcaatct tcacagtacc gtcatcttcg atttcgatgg
    22021 tggtgccagt ttcttcggtc agagcacgga ttacagaacc gcctttaccg ataacatctt
    22081 tgatcttgtc cgggttgatc ttgatggtat ggatacgcgg tgcgaactca gagatatcgc
    22141 cacgcggcgc gttgatcgcc tgttccatta cgcccaggat atgcagacgc gcacctttag
    22201 cctggttcag cgcaacctgc atgatctctt tggtgatacc ttcaattttg atatccatct
    22261 gcagtgcaga gataccgtcg cgggaacctg caactttgaa gtccatatcg cccaggtgat
    22321 cttcgtcgcc caaaatgtca gacagtacaa cgtagttgtc gccttctttc accagaccca
    22381 ttgcgatacc cgcaacggca gctttgatcg gcacacctgc gtccatcagc gccagagacg
    22441 cgccgcacac ggaagccata gaagaggaac cgttggattc agtgatttca gacacaacac
    22501 gtacggtgta cgggaatttg tccatatccg gcatgactgc cagcacgccg cgcttcgcca
    22561 gacgaccgtg accaatttca cgacgcttcg gagaaccgac catgccggtt tcgcctacgg
    22621 agtacggagg gaagttgtag tggaacagga aggtatcggt acgttcgccc atcagttcat
    22681 caagaacctg cgcgtcacga gcagtaccca gcgttgcggt aaccagcgcc tgcgtttcac
    22741 cacgggtgaa cagcgcagaa ccgtgagtac gcggcagcac gccagtacgc acatccagac
    22801 cacggatcat atctttttca cgaccgtcga tacgcggttc gcctgccagt acgcggctac
    22861 gaacaacgtt tttctcgatc gcgtgcagaa tttcacccag ttcgttttcg tccagggttt
    22921 cgtcttcagc aagcagcgtc gcgatggttt cagatttgat gacatcaacc tgcgcataac
    22981 gctcttgttt gtcggtgatg cggtaagcat cgctcaggcg agcttcagcc agtgcagcaa
    23041 cgcgcgcgtt tagcgcttcg tttaccggct ccggctgcca gtcccaacgc ggtttaccgg
    23101 cttctttcac cagttcattg atgttctgaa taacaacctg ctgttgttca tgaccgaaca
    23161 ctactgcgcc cagcatctgg tcttcgctca gcagttgagc ttcagattca accatcagta
    23221 cagcggcttc agtaccggca acaaccagat ccagtttgct ctctttcagc tcgtcctgag
    23281 tcgggttcag tacgtactgg tcattgatgt aacctacgcg ggcagcacca atcgggccat
    23341 tgaacggaat accagacaga gacagcgctg cggaagcacc aatcatcgcg acgatatccg
    23401 ggttaacttg cgggttaaca gaaaccacgg tggcgataac ctgaacttcg ttgacgaagc
    23461 cttccgggaa cagcgggcga atcgggcggt caatcagacg cgcgatcagg gtttcgcctt
    23521 cgcttgggcg gccttcacga cggaagaagc tacccgggat acgaccagca gcgtaggtac
    23581 gctcctgata gttaacggtc agtgggaaga agtcctgacc tggtttggct tttttctggc
    23641 caacaacggt aacgaatacc gcggtgtcat ccatgctaac cataacagcg gcagtagcct
    23701 gacgagccat catgccggtt tccagagtca cggtgtgttg gccgtactgg aatttacgaa
    23761 cgatcggatt aagcaatgta atatcctttc tctttcttag acagtacctt acggcactgg
    23821 tgttaatacc cgatcttctg cgcatcctcg cgactaatga caaccctaac ccagctctat
    23881 gtgggtaaag cctctcatta gccgcgcgaa cctctgcaac ggaagatcat tcatagcaac
    23941 aatacattag tttccagtga attgctgccg tcagcttgaa aaaaggggcc actcaggccc
    24001 ccttttctga aactcgcaag aattagcgac gcagacccag gcgctcgatg agctgggtgt
    24061 aacgtgctac gtctttacgt ttcaggtagt cgagcagttt acgacgctga gaaaccatgc
    24121 gcagcagacc acgacggctg tggtgatctt ttttgtgctc tgcaaagtgg ccctgcaggt
    24181 ggttgatctg tgcagtcagc agtgctacct gaacttcggt agaaccggtg tcgtttgcgt
    24241 cacgaccaaa ctcagaaacg attttagctg ttgcttcagt acttagagac attttaaaac
    24301 tccaaagtat atagaatgaa aggacgccga tctctaattc agcgatccca gtgtacgtta
    24361 cgcaaagtgt taaacaattt acgcgacgtt aagcggcagt attctactcg tagcgacctg
    24421 ttatcgcaag acggttaaca ttacgccggg tattcaacca ccaggcgacg aggcgcaacg
    24481 cggccttcat cgtcaatttc gcccataccg ataaatttgc cgttctcacc ttccgtgacg
    24541 cgaaccagtc cttccagtgg cgcaccagat gtacgaaccg ggttaccatt tttgaagtaa
    24601 acagaagacg ttaacggaag attcaccacc ggatagtccg aagctggact gtccattggc
    24661 atcagtaatg gatcaagtaa ctccgcggct ggaatatcct gctgttcagc ttgctcaaca
    24721 agttcacgca ggtgctccag ggtcaccatc cgttcaaccg gatatttact taccgccaga
    24781 cggcgcaggt aaataacatg cgcgccacag ccgagttttt cacccaggtc atcaatgatg
    24841 gtgcggatat aagtgccttt tgagcagtga atttccagct ccagctcatt gccttcatgg
    24901 cgaataaaca gcaattcata aacggtaatc ggacgcgctt cacgcggaac ttcaatgccc
    24961 tgacgcgcat attcgtacag ttttttgccc tgatatttca gtgctgaata catcgaaggg
    25021 atctgttcga tatcgccacg gaaagtatcc agtgccgctg ccagctgctc tgcgctaaag
    25081 gttaccggac gttcttcaac gatctgtccg tcggcatcag aagtatcggt acgctgtcca
    25141 agacgcgcaa tgacccgata gcgtttgtcg gagtccagca gatactggga aaacttcgtc
    25201 gcttccccga ggcaaatcgg caacatgccg gtcgccagcg ggtccagcgc accggtatgc
    25261 ccggcacggt tggcgttata tatacgtttc actttttgca gcgcatcgtt gctggacata
    25321 ccctgaggtt tatccagcaa caaaacgccg ttaatgtcgc gaccgcgacg acgaggacga
    25381 ctcattagtc ctccttgctg tcgtccgggt taacacgacg ttcttcgtca tgtttgacca
    25441 cgctggtcac caggtttgac atgcgcatcc cttcaaccag agagttgtcg tagaagaagg
    25501 tcagttccgg cacgatacgc aggcgcatcg ctttccccag caggctgcgg atgaaaccag
    25561 aagcttcttg caacgctttg atgcccgctt taaccgcgtc ttcatctttg tcgttgagga
    25621 acgtcacata tactttggca tacgccaggt cgcgagacat ttcgacaccg gaaacggtgg
    25681 tcatcatgcc caggcgagga tctttaattt cacgctgcag gatgagagcg atctcttttt
    25741 gcatttcctg cgctacgcgc tgcgggcgac caaattcttt cgccataata aattctcctg
    25801 acaaaaaagg ggctgttagc ccctttttaa aattaatttc aggtggaagg gctgttcacg
    25861 ttgacctgat aagacgcgcc agcgtcacat caggcaatcc atgccggatg cagcgtaaac
    25921 gccttatccc gcatggaacc ctaaaaacct taagcaatgg tacgttggat ctcgatgatt
    25981 tcgaatactt cgatcacatc gccagtgcgg acgtcgttgt agttcttaac gccgatacca
    26041 cattccatac cgttacggac ttcgttaacg tcatctttga agcggcgcag ggactccagc
    26101 tcgccttcgt agataaccac gttgtcacgc agaacgcgga tcgggttgtg acgtttaacc
    26161 acaccttcgg taaccataca gcctgcgatg gcaccaaatt tcggcgattt gaacacgtca
    26221 cgaacttccg ccagaccgat aatctgctgt ttcagttccg gagacagcat accgctcatc
    26281 gccgctttca cttcgtcaat caggttatag atgacggagt agtaacgcag atccaggctt
    26341 tccgcttcaa tcactttacg tgcagaggca tcagcacgta cgttaaagcc aaccaggatg
    26401 gcgttggacg ccgcagccag ggtggcgtcg gtttcggtga taccacctac gccagaaccg
    26461 atgatcttca ctttaacttc gtcagtagac agtttcagca aggagtcgga gatcgcttcg
    26521 acagaaccct gtacgtctgc cttcaggacg atattcactt cgtgaacttc gccttcggtc
    26581 atgttggcga acatgttctc gagtttagat ttctgctgac gcgccagttt aacttcgcgg
    26641 aatttaccct gacgatagag tgcaacttca cgcgctttct tctcgtcacg tacaacggta
    26701 acttcatcac ccgcagccgg tacgccggac aggccgagga tttccaccgg aatggacgga
    26761 cccgcttcca gcacttcctg acccagttcg ttacgcatcg cacgaacacg accgtattcg
    26821 aagccacaca gaacgatatc gcccttgtgc agagtacctt cacgtaccag aacggtagca
    26881 accggaccac gacctttatc gaggaaggat tcgataaccg caccgctcgc cataccttta
    26941 cgtaccgctt tcagctccag aacttccgcc tgcagcagga tagcgtccag cagttcatcg
    27001 ataccggtac ccgctttcgc agatacgtgt acgaactggc tttcaccgcc ccactcttcc
    27061 ggcaggatgc cgtactggga gagttcgttc ttaacgcgat ccggatcagc ttctggttta
    27121 tcgatcttgt tcactgcaac caccaccggt acctgcgccg ctttcgcgtg ctggattgct
    27181 tcgatggtct gcggcatcac accgtcgtcg gcagcaacaa ccaggactac gatgtccgtt
    27241 gcctgcgcac cacgagcacg cattgaagta aacgcggcgt gccccggggt gtccaggaag
    27301 gtgatcatgc cgttttcagt ttcaacgtgg tatgcaccaa tgtgctgggt aatgccgccc
    27361 gcttcgccag aggccacttt cgttgaacga atgtagtcca gcagagaggt tttaccgtgg
    27421 tcaacgtgac ccatgatggt cacaaccggc gcgcgcggtt cagccgcagc acccgtgtca
    27481 cggtcgctca ttaccgcctc ttccagctcg ttttcacgac gcaggataac tttatggccc
    27541 atctcttcag caaccagctg tgcggtttcc tgatcgataa cctggttgat ggttgccatt
    27601 gcgcccagtt tcatcatcgc tttgatgacc tgagagcctt taaccgccat cttgttcgcc
    27661 agttcgccaa cggtgatagt ttcgccgatc acaacgtcac ggttaacggc ctgagcaggc
    27721 ttctggaagc cttgctgcag cgaagaacct ttacgttttc cgcctttacc gccacgtact
    27781 gctgcgcgtg cttcttcacg atcagctttt gattcagcgt gtttgttgcc tttcttcgga
    27841 cgcgctgctt tcgcgttacg accacggcca cggccgcctt cgacttcacg atcgctttcg
    27901 tcttctgcct ggcgagcatg ttgagaagta gtgacgtgat aatcgctgga atcttcagtc
    27961 ggttccgcgt tatcagtcca tttgttttct tccgccatac gacgtgcttc ttcagcaacg
    28021 cgacgtgctt cttcttcgag tttacgacgc gcttcttctt cagctttacg cttgagctct
    28081 gcagcttcct gctcacggcg ggctttttca gcctgggcgt ttttagtcat atcgtcttgt
    28141 tgattgctca ctttgtcttt ttccgcagct tcacgtttcg cttgttcagc agcttcacgc
    28201 ttagcttgtt ctgcggcctc acgttcagct ttttgttgcg cctcgcgttt agccgattct
    28261 tctgcctcac gacgggcttg ctcttccgct tcacgctgcg cttgctcttc cgctgcaagg
    28321 cgttcagcct cttgcggatc gcgtttcaca aaggtgcgtt tcttgcggac ttcgatttgt
    28381 accgatttgc tttttccacc ggtaccagga atgttaaggg tgctgcgtgt tttacgttgc
    28441 agcgtcaatt tgtccgggcc tgaatttttc tgattcagat ggtcaatcaa agtctgtttc
    28501 tcttgtgcag acacagagtc gtcagcagac ttccggatac ctgcatcagc aaattgctgt
    28561 accaggcgtt ccacggaggt ctgtcgctct gcggccagcg ttttaatcgt tacatctgtc
    28621 atgctgttcc ttcctgctac agtttattac gcttcgtcac cgaaccagca aatattacgg
    28681 gcaaccataa tcagtgctcc ggctttttcg tcggtcaacc cttcgatatc agccagatca
    28741 tcaatgccct gttcggcgag atcttccagc gtacaaacgc cacgggcggc cagtttgaat
    28801 gccaaatcac gatctacccc ttcaaggttc agcagatcgt cagccggttt gttatcaccg
    28861 aggctttctt cctgggcctg tgcaatggtg gccagtgcat ttttagcacg ctcgcgcagt
    28921 gcttcaacgg tcggctcatc aaggccttcg atttccaaca gctctttcat cggcacatag
    28981 gccagttctt ccagcgtcga gaagccttct tctaccagaa cagtcgcgaa gtcttcgtcg
    29041 atgtcgagat atttggtgaa ggtgtcgatc gctgcgtgcg cttccgcctg atgcttagcc
    29101 tgcaggtcgt caacggtcat cacgttgagt tcccaaccgc tcagctgcga agccagacgc
    29161 acgttctgac cgttacggcc aatcgcctgc gccaggttac cggcttcaac ggcgatatcc
    29221 atggtgtgtt tatcttcatc caccacgata gaagcaacgt ctgccggtgc cattgcgtta
    29281 atcacgaact gcgccgggtt atcatcccac aggacgatat cgatacgctc gccacccagt
    29341 tcagtagaca ccgcctgaac acgcgcgcca cgcataccta cgcaagcacc taccggatcg
    29401 atacgtttat cgttggtttt caccgcgatt ttcgcacgag aacccggatc gcgagccgct
    29461 gctttaattt caatcacttc ttcgccgatt tctggcactt caatacggaa cagttcgatc
    29521 agcatttccg gcttggaacg agtgacgaac agttgcgcgc cacgcgcttc cgggcgaacg
    29581 gaatagagca cgccacgaac gcggtcgcca gggcggaagt tttcacgcgg cagcatatct
    29641 tcgcgcagga tcacggcttc agcgttgttg cccagatcca gagagatgtt gtcgcggttt
    29701 acttttttca ccacgccggt gatgatttca ccttcgtgtt cacggaactg atcaaccacc
    29761 atcgcacgtt cggcttcacg cactttctgc acgataacct gttttgccgt ctgggtagtg
    29821 atacggtcaa aggtaacaga ctcaatctga tcttcaacgt aatcgcccag gttcaggctt
    29881 tcatcttcat aacgtgcggc ttcaagggtg atttccttgg tcggctgggt gacttcatca
    29941 acaactaacc agcgacggaa agtgtcaaaa tcaccgcttt tgcgatcgat ctgtacgcgg
    30001 acgtcgatct cttgttcata ttttttcttt gttgctgtcg ccagcgcgct ttccaatgct
    30061 tcgaaaatct tctcgcgagg tagcgccttt tcattggata cggcttcaac tacagccaaa
    30121 atttctttgt tcatcgcggg cttttcacct catccagact attaaaagtg gggaaccagg
    30181 ttcgccttct ggatattact cagcgcgaac acttcatctt taccttcgac ggtaactgtg
    30241 atcatttcac cgtctaccgc tttgataacg ccctgccatt tacgacggtt ttgtaccgcc
    30301 atacggagaa ccagagtcac ctcttctccg acaaaacggg cgtagtgttc agccgtgaac
    30361 agtgggcgat cgagacccgg tgaggagact tccaggttat aagcaacggt gatgggatct
    30421 tcaacatcca gcacagcact tacctggtgg ctcacatcag cacaatcatc aacattgatg
    30481 ccatcttcac tatcaatata gatgcgcagt gtggatgtgc gaccgcgaat aaattcgatg
    30541 ccaaccagtt caaaacccag gacctcaact ggcgcagtaa tcatctctgt taatttttgc
    30601 tctaatgtgg acaagcccac ccccaagaca taaaaaaagg gcctaaagcc cagttattct
    30661 gtagtcagat aacaaaaaac cccgataaat cggggcttta tataactgaa ccctataacc
    30721 gcaactgcgg tctggagcac tttccagaag gattttttca aatcccacta cgaaggccga
    30781 agtcttcaca gtatatttga aaaaggactc taagggaaag tggttgcggg ggccggattt
    30841 gaaccgacga ccttcgggtt atgagcccga cgagctacca ggctgctcca ccccgcgcct
    30901 gaaacgtggc aaattctact cgttttgggt aaaaaatgca aatactgctg ggatttggtg
    30961 taccgagacg ggacgtaaaa tctgcaggca ttatagtgat ccacgccaca ttttgtcaac
    31021 gtttattgct aatcatgtga atgaatatcc agttcacttt catttgttga atacttttgc
    31081 cttctcctgc tctcccttaa gcgcattatt ttacaaaaaa cacactaaac tcttcctgtc
    31141 tccgataaaa gatgattaaa tgaaaactca tttattttgc ataaaaattc agtgagagcg
    31201 gaaatccagg ctcatcatca gttaattaag cagggtgtta ttttatgacg acgattctca
    31261 agcatctccc ggtaggtcaa cgtattggta tcgctttttc tggcggtctg gacaccagtg
    31321 ccgcactgct gtggatgcga caaaagggag cggttcctta tgcatatact gcaaacctgg
    31381 gccagccaga cgaagaggat tatgatgcga tccctcgtcg tgccatggaa tacggcgcgg
    31441 agaacgcacg tctgatcgac tgccgcaaac aactggtggc cgaaggtatt gccgctattc
    31501 agtgtggcgc atttcataac accaccggcg gcctgaccta tttcaacacg acgccgctgg
    31561 gccgcgccgt gactggtacc atgctggttg ctgcgatgaa agaagatggc gtgaatatct
    31621 ggggtgacgg tagcacctac aaaggaaacg atatcgaacg tttctatcgt tatggtctgc
    31681 tgaccaatgc tgaactgcag atttacaaac cgtggcttga tactgacttt attgatgaac
    31741 tgggcggccg tcatgagatg tctgaattta tgattgcctg cggtttcgac tacaaaatgt
    31801 ctgtcgaaaa agcctactcc acagactcca acatgcttgg tgcaacgcat gaagcgaagg
    31861 atctggaata cctcaactcc agcgtcaaaa tcgtcaaccc gattatgggc gtgaaattct
    31921 gggatgagag cgtgaagatc ccggcagaag aagtcacagt acgctttgaa caaggtcatc
    31981 cggtggcgct gaacggtaaa acctttagcg acgacgtaga aatgatgctg gaagctaacc
    32041 gcatcggcgg tcgtcacggc ctgggcatga gcgaccagat tgaaaaccgt atcatcgaag
    32101 cgaaaagccg tggtatttac gaagctccgg ggatggcact gctgcacatt gcgtatgaac
    32161 gcctgttgac cggtattcac aacgaagaca ccattgagca gtatcacgcg catggtcgtc
    32221 agttgggccg tctgctgtac caggggcgtt ggtttgactc ccaggcgctg atgctgcgtg
    32281 actctctgca acgctgggtt gccagccaga tcactggtga agttaccctg gagctgcgcc
    32341 gtgggaacga ttattcaatc ctgaataccg tctcagagaa cctgacctac aagccagagc
    32401 gtctgacgat ggaaaaaggc gactcggtgt tctcgccaga tgatcgtatt ggtcaattga
    32461 ccatgcgtaa cctggatatc actgataccc gcgagaaact tttcggttat gccaaaactg
    32521 gcctgctttc ctcctctgcc gcttcaggcg tgccgcaggt ggagaatctg gaaaacaaag
    32581 gccagtaatt cgacatcaac cctgcccttc aggggtgggg ttaccttgct tatcctctgt
    32641 aaactccttt ctgagcatca cataatcgaa aacatcatgg tttgcatcca caacccgtga
    32701 gtctccttta tagtgtgcaa tcacttcctc aagcgtttgc ggctgttccg gctttgttac
    32761 ccccatccac gcattaataa ggtaattatt gtaagctgtc gaaaagatgt tgttttccgt
    32821 tgtgcgatcc acgccatccc caagaacggg gctataccag ataaacatcg ggacatgata
    32881 tgcctgctgg ctagcctccc tgcctccatg aaaatagacg ttcttcttcg tagggtcacg
    32941 ttccaggccg tggtcggcaa aatacatgac cgaggcgcgg cgatctttta ataattcaaa
    33001 aacctgacct agcaaactat ctgtgtaatg aatggagttg tcatagcagg catcctgatc
    33061 gtcctgcggt tgaaacacgg cgctggattg cggataggcg ctacaagccg gttcatggct
    33121 tccatttaaa tgaagaacaa tcagtttctt ttgctgcgta ttttgctgta atgcttgcga
    33181 taaatgcggc aacaacaatt catcaaatcc tctgacataa actgtttcca tggcgcgcat
    33241 ggcgatactg gtaactgctg taccattctg ccgaaaagcg gattgcgagc ttagccagaa
    33301 agtctgaaat cctgcttgat tagccatatt aataatgttg tcggggtaat tatgaatgtc
    33361 atgactcaaa acagaatcag cagttaaaga aaggggaacc gacagcgcag tgtaaggtgc
    33421 gccgcttatt gcttgattaa acagtttgat ctgttttctt tgtgcttcaa cttgcggtgt
    33481 cgtagagcgt gtatatccat acaaagacat attgtcgaca cgtacagact cccccacaat
    33541 caacacgtag gtatcaatac ctgtatccct gactgataat tgaaaatacg gcaccgtgtt
    33601 tgcaattgag agtaatcttt gatgctcttt cgctgctaaa gcaaaatagt tgagattgaa
    33661 aaacggcgta taggtagcaa atcgcgacgc tagtatatat ggactgaacg cttttttatt
    33721 ttttgcatct ttataagcaa attgacaagc ggaaaataaa ctgcccgaaa tgacaatcag
    33781 caataatatt cctgtcactt tttttgtcgg caaggaaaca tcatatttta ttattactgc
    33841 caaaaaaaga agggataaaa aagcaaaggc acatagataa gggatataca tccccagcat
    33901 tttgacaact tcatccggat cactctggag cacactaatc gcaaatccat cattgaaagt
    33961 tgtaccaaag gtacaccatg aatagaggct aatactcatg tctgccgcag tcagtaacac
    34021 aaatggtgcg gcaacaagca ggcgaagcgg aagggatgat atacgtttta caaccaggat
    34081 ggtcagaacg aagaacagca agcgctgaac catatgcgct ccggaagaag cgactaagtt
    34141 cgtaatacca aaaacaataa cacaaagata caacaaccaa tgagatttaa aagttctagc
    34201 aaatttgttg aatactgtca tccagaaatc caagttcaca accaatataa acaattatca
    34261 acaatgttta attttatatc agacatgttt ttcaactctg atccatatca gaacgaaaca
    34321 ctgttagttt tttcttttta aatgatgcgg ccattgcgtt ctcagtaatt aaataacatt
    34381 atcaatgcgt ctctaaacat tacgcagaac gtagccatca gtcgttatac tgacaggagc
    34441 aggatggttt atcgagaagt aaacatatcc gtattcgtac cggaactgga gttgacacaa
    34501 taaagtgcca attatgtcag tagaagggaa aaatttataa ctaaggcgta ccggcaccat
    34561 cgtttcaagg taccagctac gagtaaagca actggacgag atacagatac ctgacaacca
    34621 ttcctcagac caggaccaaa acgaaaaaag acgcttttca gcgtctcttt tctggaattt
    34681 ggtaccgagg acgggacttg aacccgtaag ccctattggg cactaccacc tcaaggtagc
    34741 gtgtctacca attccaccac ctcggcacgg atactacttt ttagttcggg atatcgctgg
    34801 tcggcttagc cggagcagct ggctgagttt gttcggtttt cgccggtgca ctcagatttt
    34861 cccattcgct acctttattg gttttgttgc tattgatgtt acccagcacc agactgatga
    34921 tgaagaataa cgttgccagc agcgccgtca tgcgggtcat gaagttacca gaaccacttg
    34981 aaccaaacag cgtagcggaa gcgcctgctc cgaaggaggc tcccatatca gcgcctttac
    35041 cttgctgcag catgatcaga ccaacaaggc caattgccac aataaggaaa actactaaaa
    35101 gagcttcata cataatcaac ctgttccttg cggagttgcc gcgtaccaat gcttcaacca
    35161 ataaagcggg agtttttaat ctttcccact gaagcgggtg tgaatactaa ccaaagcgaa
    35221 tgaccttcgc aagggcaatt ttatcgcatt gtatcaactg cggaaaaaaa cagcaaaacc
    35281 gatgtgttcg ctgagaaaaa aggcgacaat cgccgccttt ttagccagtt atctaacgct
    35341 ttaaacggct tttactgcat cggcgatgcg gtgtgcaaat tcagtcacct gcgcttcgtc
    35401 ttcgccttcc accatcacgc gaattaacgg ttcggtgccg gatttacgca gcaacacgcg
    35461 tccacggttg cccagcgcag cttcaacctc tgcggtcacg gctttaactg actcatgctc
    35521 aagtggatcg ccgctacctg cggtgtaacg tacgttaacc agaatctgcg ggaacatttt
    35581 catgccgctg caaaggtcgt gcaggctcat atggttacgt gccatcgccg ccagcacctg
    35641 caagccagca acgatgccgt caccggtagt agttttatcc agcaggatca catgaccgga
    35701 attctctgca ccgatacgcc agcctttctc ctgcattttt tccagtacgt agcggtcacc
    35761 cactttcgcg cgcgcaaatg gaattcctaa ctgtttcagc gccagttcaa gccccatgtt
    35821 gctcatcaat gtacccacag cgccaccacg cagctggccc tgacgaagac cttcacgcgc
    35881 gatgatatac atgatctgat cgccatcgac tttattgcct tcatggtcaa ccataatcac
    35941 gcgatcgcca tcgccgtcga aggcaatacc gagatccgct ttttcagcca gcacacgagc
    36001 ctggagcgcg cgaacgtcgg tagcccccac ttcggcattg atgtttacac cgtttggctc
    36061 acaaccgata gcgataacgt tcgcccccag ttcgcgcagc acgttcggcg cgatgtgata
    36121 agtcgcaccg tttgcacaat ccaccacaat cttcagttca ctgaggctaa gttcgttcgg
    36181 gaacgtggct ttgcaaaact cgatatagcg acccgcggca tcaacgatac ggctggcttt
    36241 acccagttct gccgaatcaa cgcagctgat ctccttttcc atttccgctt cgatggcctc
    36301 ttctaccgca tccggcagtt tggtgccgtc gatagagaag aatttaatgc cattatcgta
    36361 gaacgggtta tgcgatgcag atatcacaat tccggcctct gcgcggaagg tacgcgtcag
    36421 ataagccacg gccggtgttg gcatcgggcc agtgaagagt gcggaaaggc ccgctgccgc
    36481 cagacccgct tccagtgctg actccagcat atagccagaa atacgcgtgt ctttaccaat
    36541 aataatctta cgggagccgt ggcgcgccag cactttaccc gcggcccaac ccagcttaag
    36601 cacaaaatca ggtgtgatcg gcgcatcccc tacacgacca cgaatcccat cggtaccgaa
    36661 atatttacga ttactcatag cgtttgtttt cctttgcaga cagagtggct tccaccaccc
    36721 gcatcgcttc tacggtttct ttgacgtcat gaacacgaat gatgtgcgcg ccttgcattg
    36781 cggcaatgac cgcacaggcc agactaccgc tcaggcgctc ggacggcccc acgttcagca
    36841 gctgcccaat catcgatttt cgtgacatac ccaccaacag cggcaggttg aaatggtgaa
    36901 attcagccag gcgcgccagt aatgaatagt tatgggagag atttttaccg aaaccgaatc
    36961 cggggtcgag caacaatttc tcttttgcga tacccgcctg ctcgcaacgt gctatttgct
    37021 caataaagta gcgattcact tctgcaaaga catcgtcata cttcggagct tcctgcatgg
    37081 tttttggatt tccctgcata tgcatcagac aaaccggtaa accggtttct gcagccgcct
    37141 ccagagcgcc aggttcggaa agggagcgga tatcattaat aatgtgagcg ccaactttcg
    37201 ctgactcacg gatgacttct ggtttggatg tatcgactga gatccagact tcgaagcgtt
    37261 gagcaattgc ctcaaccaca ggaataacac gttgcaactc ttcttcaacg ctaacttccg
    37321 ccgcccctgg gcgcgtggac tcgccaccaa cgtcaatgat cgtcgcgcca gcgttgatca
    37381 tcagattcgc atgtttcacc gcatctatca gcgagttatg cgtgccacca tccgaaaagg
    37441 aatcaggcgt gacgttgagg atccccatta cgtgaggatg gctaaggtcc agtgaagtac
    37501 cctgggcaaa gagtttcatg atgttatccc tggtatgaat tgataagaaa aaaccccgga
    37561 gcacgccccg gggttttcgg tacaaataca gtcatctgat gcgggaactt acttgtcgcc
    37621 taactgctct gacatggtgt tacccgggtt cggcgtacgc ggttcatcaa ccggacgagg
    37681 agcctttgga ctaccattgt cgccagaatt gttagaagcg cctggttctt cccagcccgc
    37741 tggcggacgt acatcgcgac gtgccatcag gtcatcaatc tgcggtgcgt cgatagtctc
    37801 atatttcatg agagcatctt tcatcgcatg cagaatatcc atattgtcgg tcagaagctg
    37861 acgcgcacga ttatagttac gctcaatcag tgctttcact tcctggtcga tgatacgtgc
    37921 agtttcatcg gacatatgtt tcgctttcgc tacgctacgg ccgaggaaca cttcaccttc
    37981 ttcttccgcg tacagcagtg gacccaattt ctcagagaag ccccactgag tcaccatgtt
    38041 acgtgccagg ttggtcgcaa ctttaatatc gttggacgca ccggtagata catgttccgg
    38101 cccgtagatg atctcttctg ccagacgacc accgtacagc gtagaaatct ggctttccag
    38161 tttctgacgg ctggcgctga ttgcgtcgcc ctcaggcaag aagaaagtca cacccagcgc
    38221 acgaccgcgt gggataatcg tcactttgtg caccggatcg tgttccggca ccaggcgacc
    38281 gataatcgca tgacccgctt cgtggtaagc cgtcgattct ttctgcgctt ccgtcatcac
    38341 catggagcga cgttccgcac ccatcatgat tttgtctttc gctttctcga actcaaccat
    38401 cgacacaacg cgtttgttgc cacgagcagc gaacagtgcc gcttcgttca ccaggttcgc
    38461 caggtcagca ccggagaaac caggagtacc acgggcaatg attgccgcgt cgatatcggg
    38521 tgccaatggt acgcgacgca tgtgaacttt caggatctgc tcacgaccgc gaacatctgg
    38581 caagccgacc acaacctgac ggtcgaaacg gccaggacgc agcagggccg ggtcgagaac
    38641 gtccggacgg ttagtcgcgg cgataacgat gataccttcg ttaccttcga agccatccat
    38701 ctcaaccagc atctggttca gagtctgttc acgttcatcg tgaccaccgc ccagaccagc
    38761 gccacgctgg cggcctacgg cgtcgatttc atcgataaag atgatgcacg gtgccgcttt
    38821 cttcgcctgt tcgaacatgt cacgaacacg ggatgcaccc acaccgacga acatttctac
    38881 gaagtcagaa ccggagatag taaagaacgg aactttcgct tcgcctgcaa tcgctttcgc
    38941 cagcagcgtt ttaccggtac ccggaggacc gaccatcaag acgcctttcg ggatcttacc
    39001 gccgagtttc tggaagcggc tcggctcgcg cagatactca accagttcag caacttcttc
    39061 ttttgcttcg tcgcagcccg caacgtcagc aaaggtcgtt ttgatctgat cttccgtcag
    39121 catgcgcgct ttgctcttac caaacgacat ggcacctttg ccaccgccgc cctgcatttg
    39181 acgcatgaag aagatccaga caccaatcag caacagcatc gggaaccagg agatgaagat
    39241 agaagccagc aggcttggtt cttcaggcgg ttcaccgaca accttgacgt tcttggtcaa
    39301 caggttatcc agtaatttcg gatcctgaac cggaatgtaa gtggtataac ggttactatc
    39361 tttcttggta acgttgattt cacgtccgtt gatacgcgct tcacgaacct ggtcgttatt
    39421 gacctcttgt aggaaggtag agtaatccac cttacggcca ttagactcgc tgggcccaaa
    39481 gctctggaat actgacatca gcacaacggc aatgaccagc cagagtatta ggtttttcgc
    39541 catgtcactc aagggattaa cctcttatta caactgtgtt aaaaacagcg tcaggatact
    39601 ctatatccag catctttcaa actttcgtct gaaatctccc ggttagggtt tacgcccggt
    39661 cgctacaata tacacttccc gcgaacgtgc acgagaagag tccggcttac gaactttgac
    39721 cttcgtaaac agggagcgaa tttcccttag atactcatcg aaaccttcgc cctggaacac
    39781 cttcactaca aaactgccac ctggcgctaa tacatcacga cacatttcta gcgccagttc
    39841 caccagatac atggcacggg ggatatccac cgccggtgtt ccgctcatgt ttggtgccat
    39901 atcggacatg acaacctgga ctttgctgtc gccaacgcgc tccagcagtg ctttcatcac
    39961 cagttcatca cgaaaatcgc cctgaagaaa gtccacacca acgataggat ccataggtaa
    40021 aagatcgcaa gcgatgatgc ggcctttgcc gccaatttgg gtgaccacat attgtgacca
    40081 accacccgga gcagcaccaa ggtcgacaac cgtcattccc ggtttaaaga gtttgtcact
    40141 ttgctgtatt tcatcaagtt taaaccaggc acgggaacgt aacccctttt tctgtgcctg
    40201 ttgaacatat ttatcgctaa agtgttcctg aagccagcgg ctggagctgg cagaacgctt
    40261 cttacctgtc atttaacttt cccatgggga taactcatcg taaccaattg cgtaaatttt
    40321 tacgcgccta tttggtgata tatgggagat ggcggtagaa tgacccgttt tcaatcccaa
    40381 cgtaagcaaa aaatacgatg aatctgagta ctaaacaaaa acagcacctg aaaggtctgg
    40441 cacatccgct caagccagtt gttctgcttg gcagtaatgg tttgaccgaa ggggtgctgg
    40501 ccgagattga acaagcgtta gagcaccatg aactcatcaa ggtgaaaatc gccaccgaag
    40561 atcgcgaaac taaaaccttg atcgtggaag ctatcgtgcg cgaaaccggc gcctgtaatg
    40621 tacaggtcat cggtaaaacg ctggtgcttt atcgcccaac taaagaacgt aaaatctcgc
    40681 tgccacgcta agattatcct aaagttacac acatttgctg tgtaaaacga ggggttttcc
    40741 gcaggcagga gagcaaaatg ccacgctctg ttcgttgata aaaggccgca tagcggcctt
    40801 tttcctttct ttacaataca tcaacatctt gagtattggg taattcttac aggtattcca
    40861 ccttaattac ttcaaattct acttcgccgc ccggcgtttt gatgaccaca acatcatctt
    40921 cttctttgcc gatcaggcca cgagcaatag gcgagtttac agaaatcagg ttttgtttaa
    40981 agtcagcttc gtcatcgcca acgatgcgat aagtctgttc ttcgtcagaa tccagattca
    41041 gcaccgttac ggtagcacca aaaataacgc gcccattgtt gggcattttg gtgacatcaa
    41101 tcacctgcgc gttcgacagc ttggcttcga tgtctttaat acggccttcg cagaaaccct
    41161 gctgttcacg agctgcgtgg tattcggcgt tttctttcag gtcgccatgc tcacgcgctt
    41221 ccgcgatagc agcaatgatt tcaggacggc gcacagattt cagaaaatcc agctcttcgc
    41281 gtaatttttc agcgccgcgt aaggtcatcg gaatagcttg catttgttat acctcttgaa
    41341 tattcctgat agggcaagtc ttcacccacc ccggctgttc ggcctgcccg gcataactcc
    41401 ttaccgggac cagaagcaaa aaaataccga cccgggtaca agtcccaggt cagctacaat
    41461 tcacattttg atagtcattt taccctgaag ttcccgaagg gtcatcgttt actttatagg
    41521 gcgttgcgcc gtagtatgac ggctcgattc caggttgtta gcgcgagatt atgcgatttt
    41581 ccagatttat catcggattg accagctgta tagcgttcag tgttcaggcc gcaaatgttg
    41641 atgagtacat tactcaactc cccgctggtg ccaaccttgc cctgatggtg caaaaagtcg
    41701 gcgcgtcggc ccccgctatt gattaccaca gtcagcagat ggcgctgcct gccagtaccc
    41761 agaaagtgat tactgcgctg gcggcgttga ttcaactcgg ccccgatttt cgttttacca
    41821 cgacgcttga aaccaaaggc aatgtggaaa acggcgtact taagggtgac ttagtggcgc
    41881 gatttggtgc cgatccgacg ttaaaacgtc aggatattcg caatatggtc gcgactttga
    41941 aaaaatctgg cgtcaaccaa atcgatggca atgtgttgat agatacctcc attttcgcca
    42001 gccacgataa agcccccggc tggccatgga atgacatgac acaatgcttt agcgctccgc
    42061 ctgccgccgc catagttgac cgcaactgtt tctccgtctc gctctacagt gccccaaagc
    42121 ctggtgatat ggcttttata cgcgtggcat cttattaccc cgttacgatg ttcagccagg
    42181 tacgcaccct cccccgtggt tctgccgaag cgcaatactg cgaactggat gtggtgccag
    42241 gcgacctgaa ccgctttacg ctgacgggat gcctgccaca acgttctgag ccgctcccgt
    42301 tggcttttgc cgtgcaggat ggagccagct atgccggtgc aattctgaaa gatgagttaa
    42361 aacaggcggg tatcacctgg agcggaacac tgctgcgcca gactcaggtt aacgaacctg
    42421 gaacggtagt tgccagtaaa cagtcggccc cgctgcacga tctgcttaag attatgctga
    42481 aaaagtcgga caacatgatc gccgatacgg ttttccgcat gataggccat gcgcgcttca
    42541 atgtgcctgg aacatggcgg gccgggtcgg acgccgtgcg tcagatcctg cgccagcaag
    42601 ccggtgtcga tattggaaac accattattg ccgatggttc agggctttcg cggcataacc
    42661 tgattgcccc cgccaccatg atgcaggtgc tgcaatacat tgcccaacac gacaatgaac
    42721 ttaactttat ctccatgctg ccgctggcgg gctatgacgg ctctttgcag taccgtgcag
    42781 gtctgcatca ggcgggcgtg gatggaaaag tctcagcgaa aaccggttcg ttgcaggggg
    42841 tatataacct ggcgggattc attaccacag cgagcgggca acgaatggcg tttgtgcaat
    42901 atctttctgg ctatgcagta gaacctgcgg atcagcgtaa tcgccgtatt ccgttagtgc
    42961 gttttgaaag ccgtttgtat aaagatattt atcagaacaa ttagtcaaaa agaaaccccg
    43021 gcacatggcc ggggcttcag attattgaca aagtgcgctt tgtttatgcc ggatgcggcg
    43081 taaacgcctt atccggccta caaaatcgtg caaattcaac atattgcaat tctcttgtag
    43141 gcctgataag cgtagcgcat caggctgatt tggcgtttat catcagtgat taacgcttgt
    43201 aaatgaactc aacgccttct tcgtcgtctt cgtcccagtc gtcatcccag tcttcatcat
    43261 cctcttcagc aatctcttca agctgctggc gatgataatc atcccacatg aattcgactt
    43321 tctctggctg tttcgcttct tcagcctgca cgaccgggtt ttcaatgata aaggtcatca
    43381 catcccagca gagatctttc acgcccagtc cactcgccgc agagatcaga taatatttat
    43441 cttcccagcc cagcgcctca gcgatcgctt tcgctttctc ttcggcttct accttatcca
    43501 gcagatcgat cttgttgaac actaaccaac gcggtttcgt cgccagatcc tggctgtatt
    43561 tttccagctc gctgataata atacgcgcgt tttcaaccgg atcggtgccg tcaatcggat
    43621 cgatatcgat gaggtgcaac aggacgcggc aacgttccag gtgcttcagg aagcgaatgc
    43681 ccagacctgc gccttccgca gcgccttcaa tcagtcctgg aatatcggca acaacgaagc
    43741 tcttttcgtt gtccattcgt accacaccca gacttggcac cagagtggta aacggataat
    43801 ccgccacttt cggtttagcc gccgataccg cacgaataaa ggtcgattta cccgcgtttg
    43861 gcatccccaa cataccgacg tcagccagca gcatcagctc cagcagcagc tcgcgcttat
    43921 cgcccggcgt gccgttggtt ttctgccgcg gtgtacggtt aacggacgat ttgaaacggg
    43981 tattgcccag accgtgccag ccgcccttag caaccagcag acgctgaccg tgtttggtca
    44041 tatcgcccat ggtttcacca gtaccctggt cgattacacg cgtacctacc ggcactttaa
    44101 tcgtcacgtc tttaccgcgc ttaccggtac agtcgcggct tgcgccattc tgaccgcgct
    44161 ctgcacggaa agatttttca aaacgataat cgataagcgt gttcaggttc tcgtcggctt
    44221 ccatccatac gtcaccacca tcaccgccgt cgccgccatc cgggccgcct ttcggaatat
    44281 acttttcgcg gcggaagctc acgcaaccat taccgccatc acctgcaacg accagaatcg
    44341 atgcttcatc aacaaacttc attttattct ccgtaaatca ttcgcctgcg cggggttgcg
    44401 ataccaccgt tgtatgctta cgtaatccgc cccaaatacg atgaccaatg gcggaataca
    44461 tcgcgcccgc aaccacgaca aacgcaccga gataacctaa aaggtttaac atcggtctgg
    44521 cgaagaaatc gggccaggcc agtgataaaa gatctgaaaa aaacagcgta aacagtgggg
    44581 tgagcgtgat gatcgcgctc acctgcgctg cctgccagcg agccatcgct tccgccaggg
    44641 cgccatatcc taccaaggta ttcagtccgc aaaaaattaa acatgcgagc tgccagtggc
    44701 taagctgcgc tatcactcca ggctttgcca gagggaagag cgcaattgta cataaagtgt
    44761 acagtaaaaa caggatctgc ggtgaggcca gccgacgcaa taaaaccttt tgcgccacgc
    44821 cataactcac ccaaaccgtc gccgcaccga ccccaaagat aactccccag gtgtaatcgg
    44881 tgagctttgt aaatatctcg accagactgg tgttaaaaaa catcaccagg ccgctcagga
    44941 gcatcaatgc ccctacaacc tgagtgctgc gcattttctc tttgaggata aatacgctgg
    45001 caaccatcat gccaactggc gagagttgcc caatcacctg cgaagcggtc ggactcaggt
    45061 attgcaagga tgagctgaac aggatgaagt tcccaaacag cccggcggtc gccactgcca
    45121 acaaaatcaa ccagcgtggc ttacgaaaca cgcgtaatgg cggcaacctc ttcttcaccg
    45181 caagaatggc acccaggcca atactcgcca tcaagaaacg gtaaaacacg attgtcggag
    45241 gttccatcac ctccagcacc tgcttcattg cgattggcaa cgccccccag caaattgctg
    45301 tggtgagcgc caaaagaatg ccaatgcctg cctgctgctt cataccgtat tccctgcaaa
    45361 gcgcatttgc ggattaacgt cgcaccatgc gcatttttac cggttatcga atgtaaaaag
    45421 ccccgcaacg tgttgcgggg ctttcatccg ttaccgggac gcgaaaaact tattcagctt
    45481 cgatgctgat aaatttacgg tttttcgggc ctttaacttc gaatttcact ttaccgtctg
    45541 ctttagcaaa cagagtgtgg tcacgaccgc aacctacgtt agcgccagcg tggaatttgg
    45601 taccacgttg acgaacgatg atgctacccg ccagaacgga ttcgccaccg aaacgcttaa
    45661 cgcccaggcg tttagcttct gaatcgcgac cgttacgtgt ggagccgcca gcctttttat
    45721 gtgccatttg aaatctctcc tcaggtctta ggcgctgatg ccagtaattt tcacatcagt
    45781 gaaccactga cgatggccct gctgcttacg atagtgttta cgacgacgaa acttaacgat
    45841 tttaactttc tcgccacgac cgtgagcaac aacttcagct ttgattacgc cgccatcaac
    45901 gaaaggaacg ccgattttga cttcttcacc gtttgcgatc atcagcactt cagcgaactc
    45961 aacagtttcg ccagttgcga tgtccagctt ttccaggcga acggtctgac cttcgcttac
    46021 tcggtgttgt ttaccaccac tttggaaaac cgcgtacata taaaactccg cttccgcgca
    46081 caccttttca atgattcaga gtgcgctata aatattcaca atagggcgcg aatattacgc
    46141 aaaacgcacg cctttgacaa gtgctacagt caatacacga agaaaaaaaa cacaacttgt
    46201 acggtaacgt ttatctgtgc cattttttca gtacaatcac cctatattcc taaccataaa
    46261 ccctaagttg cctttgttca cagtaaggta atcggggcga aaagcccggc ttttgcgatg
    46321 aatttagaaa aaatcaatga gttaaccgcg caagatatgg cgggtgttaa tgcggcaatc
    46381 cttgagcagc ttaattccga cgtccaactg atcaatcagt taggctatta catcgtcagc
    46441 ggcggcggta aacgtattcg tccgatgatt gctgtactgg ctgcacgagc tgttggctat
    46501 gagggaaatg cgcatgtcac cattgctgcc ctgatcgagt ttatccacac ggcgactctg
    46561 ctacacgacg acgttgtgga tgaatcagat atgcgcaggg gtaaagctac cgccaacgcc
    46621 gcatttggca atgccgccag cgtgctggta ggcgatttta tttatacccg cgctttccag
    46681 atgatgacca gcctcggttc gctcaaagtg ctggaagtca tgtcagaagc cgtaaacgtc
    46741 atcgcagaag gtgaagttct gcaactgatg aacgttaacg atccggacat cactgaagaa
    46801 aactacatgc gcgttatcta tagcaaaacc gcgcgtctgt ttgaggctgc cgcgcagtgt
    46861 tccgggattc tggctggctg tacgccggag gaggagaaag gcctgcagga ttatgggcgc
    46921 tatctcggca ctgctttcca gttgatcgac gatttactcg attacaatgc cgatggcgaa
    46981 cagttaggta aaaatgtcgg cgacgatctg aacgaaggta aaccgacgct gccgctgctg
    47041 catgcgatgc atcatggcac accagaacag gcacagatga tccgtaccgc catcgaacag
    47101 ggtaacggtc gccatcttct ggaaccggtt ctggaagcaa tgaacgcttg tggatctctt
    47161 gaatggacgc gtcagcgtgc cgaggaagaa gcagacaaag ccatcgcagc gttacaggtg
    47221 ctcccggaca ccccttggcg agaagcactc atcggcctcg cgcacatcgc tgttcaacgc
    47281 gatcgttaat cccctcccct catcccgcgc agcgcgcggg atggttccag taagttccat
    47341 aaaaacactt attcagctct ataacacctg aaaaataggg atgtgcatct ttatatattc
    47401 tgaatattca cactctttac aggaactttt tagagcaata ggccatcagg agtatagtga
    47461 tgctcgacag aagaagtgtt ctgaatgaaa gcgactaact taaggagtga ggaaaaatgg
    47521 aaagtaattt cattgactgg catcccgctg acatcattgc gggtttgcgc aagaagggaa
    47581 cgtcaatggc ggcggaatct cgcagaaatg gtttgagttc ctcaacgctg gcgaatgcat
    47641 tatcgcgccc atggccgaaa ggagagatga ttattgcgaa agccctggga actgacccct
    47701 gggttatctg gccatcacgc taccatgatc cgcagcccca tgagtttatc tacagaacgc
    47761 agttgatgcg tagctacact aaaccgaaaa aatgagtggt ctggcggtag ccccgcgaac
    47821 ggggctgcca gctctcagac gattattcgc ctttcacacg ctcaatattt gcacctaaag
    47881 cgcgcagttt gtcttcaatg cgttcgtagc cacgatcgat gtgataaata cgatcaacca
    47941 ccgtcgtccc ttccgcaata cagccagcca gcaccaggct tgctgatgca cgcagatcgg
    48001 ttgccataac ctgtgcgcca gaaagttttt caacaccgtg acaaataacg gtattgcttt
    48061 cgatttcggc gtgcgcgccc atacggctca gctctggcac atgcataaag cggttttcaa
    48121 agaccgtttc ggtgataaac ccggtccctt ctgccaccag gttcaacagc gtgaactggg
    48181 cctgcatatc ggtcgggaat gccggatgcg gcgcggtacg tacgttaaca gccttcggac
    48241 gtttgccatg catatccagg ctaatccagt cttcgccgac ttcgatgtcc gctccagcgt
    48301 cacgcagttt cgccagcacg gcgtcgagag tatctggctg cgcgttacgg cagataattt
    48361 tgccgcgaga aatcgccgcc gccaccagga aagtaccggt ttcgatacga tccggcagaa
    48421 cgcgatagac accgccgcct aaacgttcca caccttcgat gacgatacga tcggtgccct
    48481 gaccgctaat tttcgcaccc agcgtaatca ggaagttcgc ggtatcgacg atttccggtt
    48541 cacgcgctgc gttttcaata atcgtggtgc cttccgccag ggttgcagca cacatgatgg
    48601 tcaccgttgc gccaacgctg actttatcca tcacgatatg tgcacctttc aaacgaccat
    48661 cgacggaagc tttaacgtaa ccttcttcca gtttgatggt cgcgcctaat tgttcgaggc
    48721 cagaaatgtg tagatcaacc ggacgcgcac cgatcgtaca accgccaggt agtgaaactt
    48781 gcccctgacc aaagcgcgct accagcgacc ccagcgccca gatagaagca cgcatggttt
    48841 taaccagatc gtaaggtgcg cagaatacat taacgtcgcg ggcatcaata tgcacagaac
    48901 cattacgttc tactttcgca cccagctggc ttagcagctt cattgatgta tcgacgtctt
    48961 tcagtttcgg gacgttctgg atctctaccg gttcttccgc cagtagtgcg gcaaaaagga
    49021 taggcagagc agcattttta gcgccggaaa ttgtgacttc gccctggagc ttcgttggcc
    49081 cctgaacacg aaatttatcc atttagtttg ttctcagtta acaattcata tccgctaccg
    49141 gcgaatcgcc catagctcaa aagccgttca gtttgcgatc gcgcgcccac tccgcagggg
    49201 tatacgcttt gatcgacaca gcatgaatgc ggttatccgc aatatattcc atcagcggac
    49261 catagaccgt ctgctgtttt ttaacccgac tcatgccgtc aaacaactca cccacggcaa
    49321 taacctgaaa gtggctgcca tcgccggaaa cgtggacttc ctggagggag agagcgttca
    49381 tcaacacgct ctgaatttca ttattttcca tgggatcttc aatcatcagt taataaacca
    49441 gcgaaacatc ttagagcaaa gttgcgctgg cataaataag caaaaagcct cgctgataaa
    49501 tcagacaagg ctcgacttgc aggcaggttt gccggacagg cggttaacgc catatccggc
    49561 ctgaaaaaat ttaacgaggc agaacatcag caggcaaatt atacaatttc gccagggtat
    49621 acactttgtc gtttaccccc tgaagcgtca cattgttgcc ctgctttttc gccagatcga
    49681 taagatggag cagcagtgcc agtccccccg tatccacgcg ggagacacgg ctaagatcga
    49741 tgcaggtaat ccccttcacc gcttcctcac gcatttccca aagcggtagc aaaacgtcct
    49801 gatccagctc tccggataac gccagcgtgt cacccgtctg catccagctc agtgactcgc
    49861 tcattatttt ttctcttcca gagtgatttt ctgttgagaa atcgatttca gttgcgcagt
    49921 caggccgtcg atacctttgg tacgcagcag cgttccccac tcgttttgtt tggtggtgat
    49981 catactgacg ccttcagcaa tcatgtcgta agcctgccaa ttgcccgtct gggagttttt
    50041 acgccactgg aagtccagac gcaccggcgg acggccattc gggtcaataa tggtaacgcg
    50101 aataggcaca atggttttat cgcccagcgg ctgttctggc gcaatctgat aggtttgacc
    50161 gtgatacatc gccagcgcct gaccgtaagc ctgcttcagg tactcacgga aagcggcaaa
    50221 gtaggcttca cgttgagcag gggtcgcact cttgtaatac tggcccagca ccagcgcacc
    50281 ggcgtatttc acctgtacgt atggcagcag ttcctgatca acaatggtac gcagataatc
    50341 cgggttggcc cgaatttgcg gttgctcatt cttcaggcga tcgaacgttt tctgcgccgc
    50401 ctcgtccatc agcttatacg gattggtctg gtctgccgcg gttgccgcac tcagaggtgc
    50461 aatcaccagc aaagcgacca tcattaaacg tttaaacatg cgtcggttct cctgaaatta
    50521 tttcgttgta cccacaggtt cagtggtttc attattacct ggcgcagcag ctggcgcatc
    50581 gccactattc ttattgtcat cgcctttact accgtaaagg aactgaccaa tgagatcttc
    50641 cagcaccatc gcagacttag tgtcctgaat tgtatcgcca tccttcagga tagcagtccc
    50701 cagttccggg tcttcaaaac cgacgtttaa tgccagatat tgttccccca gcaggccgga
    50761 agtacgaatg ctcagcgaac tggtatctgg aatgtggtta taacgttgtt caatttccag
    50821 cgttacgcgc ggcagatagg ttttcgggtc cagcgtaata tccgccaccc gacccacaac
    50881 aacgccacca atactgaccg gagagcgcgc tttcaggccg ccaatgttat cgaacgtcgc
    50941 ataaagcgtg taggtcggtt cagtacgtat ggacgtcacg ttcgccgcct tcaggcaaac
    51001 aaacagcgcc gccagcagtg ctgctaataa aaagataccc acccaaattt catttttttt
    51061 cgtttgcatg aactcaattc ccaaacatca atgcggtcag cacaaaatcc agccccagaa
    51121 cagccagaga cgagtggaca acggtgcgag tggttgcccg gctaatcccg gcagacgtcg
    51181 ggatggcgtc gtagccgtta aacaacgaaa tccacgtcac cgtgatggcg aacaccacgc
    51241 tcttaatcag acagttgacc agatccatac gccagtcgac ggcattttgc attgccgacc
    51301 agaagaaccc gctatcaatg cctttccaac tgacgccgac cagagatccg ccccagatcc
    51361 ccacggcgac gaaaataacc gtcaacagtg gtaatgaaat aaccccagcc cagaaacggg
    51421 gagaaataac ccgacgcagc ggatccaccg ccatcatctc catactggag agttgctctg
    51481 tagcgcgcat caggccgatt tctgcggtta gcgccgaacc agcacgcccg gcaaacaaca
    51541 acgcggcaac caccggcccc agttcacgca gtagcgataa cgccaccagc atacccagac
    51601 tggtttccgc actataagtg gtcagaacca gataaccttg cagccccaac accattccga
    51661 tgaacacgcc agaaaccaca ataatcagca tcgacaggac gccgacatta tagagctggc
    51721 gcaccagcag cggcgcatgt ttgcgaaatt ccggtttgcc gaccagcgca ttgaataaca
    51781 ttaacccggc ccgcccgaac gttctcaggg ttttaatccc tttatgtccg agcgacgcca
    51841 gcgcatttaa cagcatgagt ggcttaactc cctggtaaaa gatcagcgtg ataatcgccg
    51901 gcaggatagc ggaacggaac aggcccgtca gctatcccgt ccagaaactg acgtacgcgc
    51961 ggatcaggat tcgcctgcaa cgcctgggca ctgccatgag cgacaatttt tttgtccgcc
    52021 aggatccagg cgtgatccgc aatacttaac acttccggca catcgtgaga aaccaccaca
    52081 caagtcacgc ccagcgcgct gttcagctca gaaatcagct tcaccagtac gcccatggtg
    52141 atgggatctt gcccaacaaa aggttcatca aacatgatga gatccggctc cagcgcaatc
    52201 gcacgcgcca gcgctgcacg ccgcgccatc ccaccggaaa gttcagaagg cattagttta
    52261 gccgctccac gcagccccac ggcctccagc ttcatcatca ccgtactatg caacaatggc
    52321 gcgggaagtt gggtatgttc gcgcagtgga taggcgacgt tgtcaaatac gttcatatca
    52381 gtgaacaacg ccccggactg aaataacatg ctcatccgtt tgcgcactgt atacaggcgc
    52441 gaacgagaca tcgccggaat attctcacca tcgaaaagga tctcaccatg atctggtgcg
    52501 atttgcccgc caatcagacg gagtagcgtc gttttaccga tgcccgatgg ccccatgatc
    52561 gccgtgatct tccctcgcgg cacggtcagg gaaatattat cgaagatgca gcgattgcca
    52621 cgcgtaaaac tgacatcgcg catatcgact aaattcgcca cagactgctc cataattcac
    52681 ccttcgtctt gcgttgattt tctaagcatg gcgctcaatt taaccttgaa cccaacatat
    52741 ttacagaata ttacccgccg tggttagcga aagctggcat ttgttttact ttttagccgc
    52801 ataaagtcaa aattaagcat ccgttacggc tttctgaaaa tcttcagcgg accggcgagt
    52861 atacctgaag aaaggacgtt agatgctttt agctacggca ctgttaattg ttggtttact
    52921 tttggtcgtt tacagtgccg accgcctggt ttttgccgcg tctattcttt gccgaacctt
    52981 tggcatcccg ccgctgatca tcggcatgac ggtggtcagt attggtacat cgttaccaga
    53041 agtcatcgtc tcgcttgccg cgtctctgca cgaacaacgc gatttagccg ttggtacagc
    53101 cctcggctca aacattatca atatattgct gatcctcggt ctggctgcgc tggttcgtcc
    53161 ttttaccgtc cattctgatg ttctacgccg tgaattaccc ttaatgttgt tggtcagcgt
    53221 ggtggccggt tccgtactct atgacggaca acttagtcgc agcgatggta tctttctcct
    53281 ctttctggct gtgctatggc tgctgttcat tgttaaactt gcacgtcagg ctgaacgtca
    53341 ggggactgac agcctgacca gagagcagct tgcagagctg ccgcgtgacg gcggattgcc
    53401 cgtcgcgttt ttatggctcg gcattgcgct tatcatcatg ccagtggcca cgcggatggt
    53461 ggttgataac gccacggtgc tggcgaatta ctttgccatc agcgagttga cgatgggtct
    53521 gacggcaatt gctatcggaa ccagcctgcc ggaactggca accgcaatag cgggggttcg
    53581 caaaggtgaa aacgacattg ctgtcggaaa tatcattggc gcaaacattt ttaatattgt
    53641 catcgtgttg ggtttacccg cgctgataac gccaggagag attgatccac tggcgtacag
    53701 tcgtgactac agcgtgatgt tgctggtgag cattattttt gcgttgctgt gctggcggcg
    53761 ctccccgcaa ccgggccgtg gtgtaggggt attattaact ggcggattta tcgtatggct
    53821 ggcgatgttg tactggttat cgccaatact cgttgaataa ctggaaacgc attatgtcgc
    53881 acgtagagtt acaaccgggt tttgactttc agcaagcagg taaagaagtc ctggcgattg
    53941 aacgtgaatg cctggcggag cttgatcaat acatcaatca gaatttcacg cttgcctgtg
    54001 aaaagatgtt ctggtgtaaa gggaaagttg tcgtcatggg gatgggaaaa tcggggcata
    54061 ttgggcgaaa aatggcggca acgtttgcca gcaccggtac accttcattt ttcgtccatc
    54121 ctggtgaagc cgcgcatggt gatttaggca tggttacccc acaggatgtg gtgattgcta
    54181 tctctaactc tggtgaatcc agcgaaatca cggccttaat tccagtgctt aagcgtcttc
    54241 acgtaccgtt aatctgcatc accggtcgcc cggagagcag catggcgcgc gccgcagatg
    54301 tgcatctgtg tgttaaagta gcgaaagaag cctgtccgtt agggctggca ccgaccagca
    54361 gcaccaccgc cacgctggtt atgggcgatg ccctcgctgt cgcgctgtta aaagcacgcg
    54421 gctttactgc tgaagatttt gcgctctcac acccaggcgg cgcactgggt cgtaaacttc
    54481 tgctgcgcgt aaacgatatt atgcatacgg gcgatgagat cccgcatgtt aagaaaacgg
    54541 ccagtctgcg tgacgcgttg ctggaagtta cccgcaaaaa tcttggtatg actgtcattt
    54601 gcgatgacaa tatgatgatt gaaggcatct ttaccgacgg tgatttacgc cgtgtcttcg
    54661 atatgggcgt ggatgttcgt cagttaagta ttgccgatgt gatgacgccg gggggaatac
    54721 gtgtgcgccc tggcattctg gccgttgagg cactgaactt aatgcagtcc cgccatatca
    54781 cctccgtgat ggttgccgat ggcgaccatt tactcggtgt gttacatatg catgatttac
    54841 tgcgtgcagg cgtagtgtaa agattcaagg ataaacaaca atgagcaaag caggtgcgtc
    54901 gcttgcgacc tgttacggcc ctgtcagcgc cgacgttata gcaaaagcag agaacattcg
    54961 tctgctgatc ctcgatgtcg atggcgtact gtcagatggc ctgatttata tgggcaataa
    55021 tggcgaagag ctgaaagcgt tcaatgttcg tgacggttat ggcattcgtt gtgcgctcac
    55081 ctctgatatt gaagtcgcta tcattaccgg gcgaaaggct aaactggtag aagatcgttg
    55141 tgccacattg gggatcactc acttgtatca ggggcagtca aacaaactga tcgcctttag
    55201 cgatctgctg gaaaaactgg cgattgcccc ggaaaatgtg gcttatgtcg gcgatgatct
    55261 catcgactgg ccggtaatgg aaaaagtggg tttaagcgtc gccgtggccg atgcgcatcc
    55321 actgttgatc ccgcgcgccg attacgtgac gcgcattgct ggcggtcgtg gcgcagtgcg
    55381 cgaagtttgc gacttattac tcctggcgca gggcaaactg gatgaagcca aagggcaatc
    55441 gatatgagta aagccagacg ttgggttatc attgtgctat cactggcggt tctggtgatg
    55501 atcggcatta atatggccga aaaagacgat accgcccagg tggtcgtcaa caacaatgat
    55561 cccacctata aaagcgagca tacggacacg ctcgtctata acccagaagg ggcactaagc
    55621 tatcgattga ttgctcaaca cgttgaatat tattccgatc aggccgtttc gtggtttacg
    55681 cagccggtac ttaccacgtt tgataaggat aaaatcccga catggtccgt aaaagcagat
    55741 aaagccaagc tgaccaatga ccggatgctc tatttatatg gacacgttga agtcaacgca
    55801 cttgtgccag actctcaact tcgcagaatc acgacggata acgcgcagat caatctggtg
    55861 acgcaggatg ttacctctga agacctcgtc acgttatacg gaacaacatt taactccagc
    55921 ggtctgaaaa tgcgcggcaa cttacgcagc aagaacgccg agctgattga aaaggttaga
    55981 acatcctatg aaattcaaaa caaacaaact cagccttaat cttgtgcttg ccagctcact
    56041 tctggccgcc agcattccgg catttgccgt aaccggagac actgatcagc cgatccacat
    56101 tgaatcggac cagcaatctc ttgatatgca aggcaacgtg gttaccttta ccggtaatgt
    56161 catcgtcacc cagggcacca tcaaaattaa tgccgacaaa gtggtcgtta cccgtccggg
    56221 cggcgaacaa ggtaaagaag tgattgacgg ctacggtaaa ccggcaacgt tctaccagat
    56281 gcaggacaac ggtaaacccg ttgaaggtca cgcttcccag atgcactacg aactggcaaa
    56341 agattttgtc gttctgacgg gtaatgctta tctgcagcag gtcgatagca acattaaggg
    56401 cgataagatc acttacctgg tgaaagagca gaaaatgcag gctttcagcg acaaaggcaa
    56461 gcgcgtaaca accgttctgg tgccgtcgca gctgcaggac aaaaacaaca aaggccagac
    56521 cccggcacag aagaagggta attaattcgt tatggcaaca ttaactgcaa agaaccttgc
    56581 aaaagcctat aaaggccgtc gcgtggtaga agacgtcagc ctgaccgtca actccgggga
    56641 aattgtcggt ctgctggggc caaacggtgc cggtaagacc accactttct acatggttgt
    56701 aggcattgtg ccgcgcgatg cgggcaacat cattattgat gatgacgata tcagtctgct
    56761 gcctctgcat gcacgcgcgc gccgcggtat cggctatctg ccacaggaag cctccatttt
    56821 ccgtcgcctc agcgtttacg ataacctgat ggcggtactg caaattcgtg acgacttgtc
    56881 tgctgaacaa cgtgaagacc gcgcgaacga gctgatggaa gagtttcaca ttgagcacct
    56941 gcgtgacagc atggggcagt cactctccgg gggtgaacgt cgccgtgtag aaattgcccg
    57001 cgcactggct gcgaatccga aatttattct gctcgacgaa ccgtttgccg gggttgaccc
    57061 gatctcggtt atcgacatta aacgcatcat tgagcacctg cgcgacagcg gcctgggcgt
    57121 gctgatcact gaccacaacg tgcgtgaaac actggcggtt tgtgaacgcg cttatatcgt
    57181 cagtcagggg catttgatcg cccacggcac gcctacagaa atcttacaag acgaacacgt
    57241 taagcgtgta taccttgggg aagacttcag actctgatag ggtagaagtt tgcgacgttt
    57301 tagcaggaga gtacgattct gaacatgaag caaggtttgc aactcaggct tagccaacaa
    57361 ctggcgatga cgccacagct ccaacaggca attcgtctgt tgcagttgtc gacgctggaa
    57421 cttcagcagg agctacagca ggcgctggag agtaatccgc tgcttgagca aatcgacact
    57481 catgaagaaa tcgacacccg cgaaacgcaa gacagtgaaa cgctggacac cgccgacgcg
    57541 ctcgaacaaa aagagatgcc ggaagagctg ccgctcgatg ccagttggga caccatttac
    57601 accgctggta caccatccgg caccagcggt gactacattg acgacgagct gccggtctac
    57661 cagggcgaaa cgacgcagac cttgcaggat tacctgatgt ggcaggttga gctgacaccg
    57721 ttttccgaca ctgaccgcgc tattgctacc tctatcgtcg atgccgttga tgaaaccggt
    57781 tatctgactg tcccgctgga agatattctc gaaagtatag gcgatgaaga gatcgacatc
    57841 gacgaagttg aagccgtcct taagcggatc caacggtttg atccggtcgg tgtggcggca
    57901 aaagatctgc gtgactgtct gctgatccaa ctctcccaat tcgataagac cacgccgtgg
    57961 ctggaagagg ccagactgat cattagcgat catctcgatc tgttagccaa tcacgacttc
    58021 cgcactttaa tgcgcgtcac gcgtctgaaa gaagatgtgc tgaaagaagc cgtcaatctg
    58081 atccagtcgc tcgatccgcg ccccgggcag tcgatccaga ctggcgaacc tgagtatgtc
    58141 attccagatg tgctggtgcg taagcataac ggtcactgga cggtagaact caacagtgac
    58201 agcattccgc gtctgcaaat caaccagcac tacgcctcga tgtgcaataa cgcgcgcaac
    58261 gatggtgaca gccagtttat ccgcagcaat ctgcaggatg ccaaatggtt gatcaagagt
    58321 ctggaaagcc gtaacgatac gctactgcgc gtgagtcgct gtatcgttga acagcagcaa
    58381 gccttctttg agcaaggtga agaatatatg aaaccgatgg tactggccga tatcgcccag
    58441 gctgtcgaaa tgcatgaatc gacgatatct cgcgtgacca cgcaaaaata cctgcatagt
    58501 ccacgaggca tttttgaact gaagtatttc ttttccagtc acgtcaatac cgagggcggc
    58561 ggcgaagctt cctccacggc gattcgtgcg ctggtgaaga aattaatcgc ggcggaaaac
    58621 ccagcgaaac cgttgagcga cagcaagtta acctctttgc tgtcggaaca aggtatcatg
    58681 gtggcacgcc gcactgttgc gaagtaccga gagtctttat ccattccgcc gtcaaaccag
    58741 cgtaaacaac tcgtttgacc caaccgataa ggaagacact atgcagctca acattaccgg
    58801 aaataacgtc gagatcaccg aggcactgcg cgaatttgtt acagccaaat ttgccaaact
    58861 tgagcaatat tttgaccgaa tcaaccaggt ctatgttgtt ctgaaagtgg agaaagtcac
    58921 ccacacctca gatgcaacac tgcatgtaaa cggtggtgaa attcatgcca gcgcggaagg
    58981 tcaggacatg tacgctgcca ttgatggctt aattgataag ctggcacgcc agttgaccaa
    59041 acataaagat aaactgaaac aacactaatt gtccgggcaa ttagcatgtg catggcggtc
    59101 tgttgtgcgg cacaacgggc catttgtacg gttaatgctc cgagcctgtt ccactgtttg
    59161 agtgggcagg ttcttaggtg aaattatgac aaataatgat acaactctac agcttagcag
    59221 tgttcttaac agggaatgta cgcgaagccg cgtccactgt cagagcaaaa aacgcgccct
    59281 ggaaatcatc agcgagctgg cggcgaaaca acttagcctg ccgcctcagg tggtttttga
    59341 agctatcctg acgcgggaaa aaatgggcag taccggtatc ggcaatggta ttgccattcc
    59401 gcatggcaaa ctggaagaag atactctgcg cgccgttggc gttttcgttc agctcgaaac
    59461 gcctatagct ttcgatgcca tcgacaacca accggtggac ttactttttg ccctgctggt
    59521 gccggcagac caaactaaaa cgcacctgca tactctgtcg ctggtggcga aacgtctggc
    59581 ggacaaaacc atctgccgcc gtttacgcgc agcccagagc gatgaagagc tgtatcaaat
    59641 cattacggat accgaaggta ctccggatga agcgtagtta ttcggtaatg tctcttttag
    59701 acgttgtgag gagaaacagt acatggtact gatgatcgtc agcggacgtt caggttcagg
    59761 taaatctgtc gccctgcgtg cgctggaaga tatgggtttt tactgcgtgg ataaccttcc
    59821 cgtagtgttg ttacccgatc tggctcgaac cctggccgat cgcgagattt ctgccgccgt
    59881 cagcattgat gttcgtaata tgccggagtc accagaaata ttcgaacagg cgatgagtaa
    59941 cctgcctgac gctttctcac cgcaactcct gttcctggat gccgaccgta ataccttaat
    60001 tcgtcgttac agtgacacgc gccgactgca tccgctttcc agcaaaaacc tgtcgctgga
    60061 aagtgctatc gacaaagaaa gcgatttgct ggagcctctg cgttcgcgag cggatctgat
    60121 tgtcgatacc tcagaaatgt ccgttcacga gctggctgaa atgctgcgta cccgtctgct
    60181 gggtaaacgt gaacgcgaac tgaccatggt ctttgagtct ttcggcttca aacacggtat
    60241 ccctatcgat gcagattacg tctttgacgt gcgcttcttg ccgaacccgc actgggatcc
    60301 gaaactgcgt ccaatgacag gtcttgataa acctgtcgcc gcgttcctcg accgccacac
    60361 agaagtacac aattttatct accagacgcg aagctatctt gagctatggt tatctatgct
    60421 ggaaaccaac aaccgtagct acttgacggt cgccattggt tgtaccggcg ggaagcaccg
    60481 ttcggtgtat attgcagagc aactggcaga ctacttccgc tcgcgcggta aaaacgtcca
    60541 gtcacgccat cgtacgctgg aaaaacgtaa accatgaccg tcaagcaaac tgttgaaatc
    60601 acaaacaagc tgggcatgca tgcccggcct gcaatgaagc tgtttgaatt aatgcagggt
    60661 tttgacgctg aagtgctctt acgtaatgac gaaggcaccg aggctgaagc caacagcgtt
    60721 attgcgctgc tgatgttgga ttctgccaaa ggacggcaga ttgaagttga agcgaccggt
    60781 ccacaggaag aggaagcact ggccgccgtt atcgccctct ttaattctgg ttttgatgaa
    60841 gattaatctt catcactttg acatacaact cccttcaaac tccccccgac aataagaaaa
    60901 tcacgtactg aaatcgttct caatcaacgt catttgtaca ttttgtgcgc ttttcacttt
    60961 cagaagaacc ttaagaaaac cttaagaggc attgtttagg ttttgtttaa gttaatcgac
    61021 catactggag atcgtcagaa aatatttcca ggagatggca tgattcgctt atctgaacaa
    61081 agtcccctgg gcaccggaag acatcggaaa tgttatgcgc atccggaaga tgcccaacgc
    61141 tgtatcaaga ttgtctacca tcgtggcgat ggtggcgata aagagatccg ccgtgagtta
    61201 aagtactacg cgcatcttgg tcgccggtta aaagactgga gtggaatacc gcgctatcac
    61261 ggtaccgttg agacggattg cggaaccggt tatgtctacg atgtgattgc agattttgac
    61321 ggcaagcctt ccattacgct gaccgaattt gctgaacaat gccgttacga agaagacatt
    61381 gcacaactgc gccagctact gaaacagctg aagcgttatt tgcaggataa ccgtatcgtg
    61441 acgatgtcgc tgaagccgca gaatatcctc tgtcaccgca tcagtgagtc agaggttatc
    61501 ccggtcgtct gcgacaacat tggtgaaagc acattgattc cactggcgac ctggtcgaag
    61561 tggtgttgtc tgcgtaagca agagcggtta tggaaacgat ttatcgccca accggcgctg
    61621 gctattgccc tgcagaaaga tctgcaacct cgtgagagca aaacgctggc cctcacttcg
    61681 cgcgaagctt aatccagctg gtgttgttgc ataaacggct caccgcctaa ctgatacatc
    61741 tgccgtaaaa tccacgcctg acggctacgc acgtagcccg atggcgagga gactttgaaa
    61801 cgaagtggat taggtaatac agctgccagt aatgcagctt ccgaccgggt aagtttgctc
    61861 gcgggtttgt ggaaataacg ttgtgccgca gcttcgacgc caaacacacc gtcgccaaat
    61921 tcggcgatat tcaggtaaac cgtcaggata cgctttttgc tccagaccgt ttctatcccc
    61981 agcgttaatc cggcttccag cccttttcga acccagctac gcccatccca taaaaagaga
    62041 tttttggctg tctgttgaga aatcgttgaa gcaccgcgaa tacggttttc attgcgctcg
    62101 ttgtgcgcca gggctttctc aatggaagcg acatcaaagc cccagtgctc aggaaatttc
    62161 tgatcttctg cggcaatcac cgccagtccc atccacggcg agatttgatc catactgacc
    62221 cagtcagaat gtgccacgta acgaaaattg ccatgcagcc aggcgctgac ctgtcgctcg
    62281 accattaccg ctgagaaggg aacaggcgca acgctaaaca acgcgatgcc cccgccccag
    62341 aaaacggcga ggacaaccat taaccgcaaa agaaaacggc gaacgaaact aaacaccgtt
    62401 aagcggcttt tactcattca gccagaacca gcacgcggga aaccagctta tcaatgccgc
    62461 tcgccgcttc tgcaatgttc tgcgccagca tatatgctgg ggtggtgaca atcttattgt
    62521 cttcatcaac cacgatatca tcgacaggac acggcacatg ctccgcgccc atctcttcca
    62581 gcacttctgc ggtatcgata tcagtaccga tggtcaaacg cagcgggaaa tcgaaaattt
    62641 tcggcagcat cgccggggca atacacataa aaccaagcgg ttttccggcc tgatgcatcg
    62701 cttgtgccag cgcctttaat tcacggtcaa cggtgcattc gctaccaaga ctggcaaaat
    62761 tgcttaaatt cttcgccgcg ccaaaccccc ccggcacaat caacgcatcc agttcagcgg
    62821 catcggcctg ggccagagga cggatttcac cgcgcgttat tcgtgccgct tcaatcagca
    62881 cgttgcgcgt ttccgtcatc gcttcgccag ttaaatggtt gataacatca acctgctgct
    62941 tatccggtgc aaagcagacc gcctgcgcac cgctgcgtga aatagctaac aacgtcaaca
    63001 ccgcttcatg aatttcagaa ccgtcataga cgccgcatcc gctcagaatt acgccaattt
    63061 tcttcattgt gatcatcctt tcgcaattga ctgaaacaca ttaatttttt taataaaaat
    63121 ggtacgcatc acacatttaa ctgattcatg taacaaatca tttaagtttt gctatcttaa
    63181 ctgcgtgcgg cctgaaaaac agtgctgtgc ccttgtaact catcataata atttacggcg
    63241 cagccaagat ttccctggtg ttggcgcagt attcgcgcac cccggtctag ccggggtcat
    63301 tttttagtgg cttttgccac ccacgctttc agcacttcta cgtcgtgacg ccactcttct
    63361 ttcatctctt caatccattc accgacgtta tcttcccagg caggaaggtc cggagactga
    63421 atttgctgac ccagctgttg cagatggcgt aaccccactg accccgccgc acctttaatt
    63481 ttatgtcctt cctctacaat gcctttttta tcctgcgccg tcagattcga ctccagcacg
    63541 ctgacatagc ccggcatcat cttctcaaac accgctaacc cgtcggtgat cagcttcggt
    63601 cctacaagtt cgagatactg ttccagcatg ggaatatcga gcaatgcttc tgatttactg
    63661 ttctcttctg tcgtcaccgt actctcctca tcatcctggg tatcccagaa tttcttgatc
    63721 atcgcggtta gcgccggaac cgaaagcggc ttactcagca catcatccat tccagcattg
    63781 aggtactctt gtttgtcttt cagcacgtta gcggttaagg ccaccagcgg cggtaaatcc
    63841 tcgcgcggat aacgcttcgt cagttcacga gagatatcca gcccggtcat atctggcaac
    63901 tgaatatcca gcaacaccag gtcgtattcg cccggtttaa acatctccag cgccgccttg
    63961 ccggtcatgg cgacatcaac gctgttacct aatttttcca gcacagaacg cgcaacaatc
    64021 acgttcagtt caatgtcttc caccagcagc acattcagcg ccggtaaagg catatcgtct
    64081 tcatcaaacg catcatcgac ctcttctgct accgacggtg cgtggatcgt caacgtaaag
    64141 gttgaacctt tgccctgttc gctggtaacc gtaatatcgc cgcccatatt tttcgccaga
    64201 cgacgagaaa cggccagacc aataccggtg ccggtggcag gtttaccgcc atgactgtct
    64261 ttcacctggt aatacatggc gaaaatttta tccagctcat cctgcggaat gccgatacca
    64321 gagtcttcca cttcaaaatg cagcatatcg ccttcatcgt agcgcacgcg cacggtaacc
    64381 tggccttgct gggtgaattt gacggcgtta ctgatgaggt tccacaggat ctgccgtaaa
    64441 cgcgtcccgt cggtaatgac ctgatgcggt aatggcagcg tcggctccag gttaaagcgc
    64501 aatccttttt gttgcgcctg caatgcggag agattttcca gatcggcaag gaagctggtg
    64561 aaatcaaccg gttgattatc aagctggacc ttgcgccgtt ccatcttatc catgtcgata
    64621 atatcgttaa agatattccc cagcgtgacg gccgaaacat ggatggtctt gagatatttt
    64681 tcctgctcgg cggtgagttc ggtatccagc agaatacggc tcaggccgac gataccgttc
    64741 agcggtgtac gcaattcgtg actgatggtg gagataaacg tcgttttgtc gcggctggcc
    64801 cgttcaagcg catcctgata ccgcttacgc tcggtaatgt cgcgaccaaa gcccatcaaa
    64861 ccgtgacgtt tacccacgcg gtcgtagtac ggcactttac ggatttcaaa gcaggctttg
    64921 cgcccgtccg ggtaatccag ccactgttca taggtcagtg acacattatg acggaacact
    64981 ttttcatcgg tttcaatgac ttttgcggcg gcttccggtg agtaaacatc agcaggtttc
    65041 aggtgaacca gttgtttttc gctttttccg gtcagcagct ccatcgcgcg gttacagccg
    65101 gaaaactctt tatcttcgtt acgataaaaa accaggtcgg gtgaagcatc aaggaaggaa
    65161 cgtaagaatg aggattgctg ctcgagctga atttgtgtct cttcgcgctc tttgatttca
    65221 attttcagtt ggccgaaggt ttcctgcagt tctgcttccg ctttttcacg aacggcgatt
    65281 tcctgattta gctgggcaat attatctttt aactgaacgt tgaggctcaa atcgcgctcg
    65341 cgcatctcct ccagtttttg caccagccgt gacagacgtt gtcgtgactc ctccagttgc
    65401 tcgacgacca ccgatagaaa gtagaccgcc cacggcgtaa tcagcaaacc aaagaagata
    65461 gaacgaataa catcaatgct ttcgacctga ccatgcagca ccatggttac cgccatttgt
    65521 accacaatgg caagaacgac gagggccagc gccagcaaca ttgagaagcg caccagacct
    65581 aacttcatca tcaggtcaac ataatactgc gccagcagac gaatttgctt cattagggaa
    65641 ttccttcacg acaacctgcc ccaataatac ccaattctga cagttacgtt ataaattgtg
    65701 tgagaaatgc ggaattcccc tcaacgacct actccgttgg aggtagccac ggacgtccca
    65761 gcgccgatcc ctgtacgcca tgttcattca gatagcgatc cagctcgacc attcccgtcc
    65821 atcgattttc gcaccacaga ggagcaagca gcgtcgggcg acgggcgctg gcggaaatgc
    65881 ggtggtagat cacttccggt ggcgtatggc gaatcatttc tccggcagtg agcgtgtaat
    65941 cctccagttc aataccgttc aaacgccccg cttcccaggc tttcgccata atgctgcctt
    66001 tcacaatatg cagcggatgc agctttatgc cgtccacgcc ggtttcaacc actcgctcca
    66061 gcgtttgcaa acattcagcc tgcccttcgc caggcaggcc gacaattaag tgggaacaca
    66121 ccttcagccc gcgctgacgt gccagctggg ttgtacgctg ataacaggca aaatcatggc
    66181 cgcggttgat gcgatgcagt gttttgtcgt gggcggtttg tagccccagc tccagccaca
    66241 cttcgtaacc ctggtcctta tattcgcaaa gcagatccag caccgcatcc ggcacgcagt
    66301 ccgggcgggt accaacacac aaaccgacaa tattggcctg gctcaccgcc tgctgataca
    66361 tagaacgcag cacctgaact tccgcaaagg tgctggtata cgcctgaaag taggccagat
    66421 agcgtttagc gcggttaact aaattcgcct ggtgcgccag ttgctcggca atggaacgat
    66481 gctgctgcgc ttcatcggca aacgaggcaa cattacagaa tgtgcagcca ccacgcccga
    66541 tggtaccgtc acggttaggg cagctaaaac cgccgtgcag cgtcagctta tgcacctttt
    66601 gcccataacg acgggtgaga tcaccaccaa acatattgac taatttctgt aactgcataa
    66661 tctgatagac cgcgccttga aaagaggcca aagcctgcca tttttagctc aattcggcga
    66721 tgacctggat caatcgtccc ggcctgcttt tatcaaccgc ataatcaatc aaaattaccg
    66781 aaatttcatg cataatcaca taaatcactt ttgcttatct tgtgtcagat ttttttatct
    66841 cctgatggat tttaggcaaa aacagtagca tgaaacgtca ttaccaatta aggcagtata
    66901 aaatgctggt tttgtcgtca gttcaaggca ggataagggt taacacacct ttatgacagt
    66961 caggaattga ctgtttctct aacgacttcc cttttagcct taaagataaa atccatttta
    67021 atttcagtca tttaataaag aattttgcgc taaagcacat ttctgtacca ataagcttgc
    67081 catttgacct gtatcagctt tcccgataag ttggaaatcc gctggaagct ttctggatga
    67141 gcagcctgct catcatattt atgcagtaat tgagatcccc tcttcaccgt attaaccgat
    67201 gcgaaaagga caacaagggg gcgaatgcga ggcgcgcgta tgacacgcaa accccgtcgc
    67261 cacgctcttt ctgtgcccgt gcgcagcggt tcggaagtgg ggttcccgca gagcctgggg
    67321 gaggttcacg atatgttgta cgataaatcc cttgagaggg ataactgtgg tttcggcctg
    67381 atcgcccaca tagaaggcga acctagccac aaggtagtgc gtactgcaat acacgcactg
    67441 gcccgcatgc agcaccgtgg cgcgattctc gccgatggta aaaccggcga cggttgcggc
    67501 ttgctgttac aaaaaccgga tcgctttttt cgcatcgttg cgcaggagcg cggctggcgt
    67561 ttagcaaaaa actacgctgt cgggatgctc ttcctgaata aagatcctga actcgccgct
    67621 gccgcacgcc gcatcgttga agaagaactg caacgcgaaa ccttgtcgat tgtgggctgg
    67681 cgtgatgtcc ccactaacga aggcgtgctg ggtgaaatcg ccctctcctc tctgccacgc
    67741 attgagcaaa tttttgtgaa cgccccggca ggctggcgtc cacgcgatat ggagcgccgt
    67801 ctgtttatcg cccgccgccg cattgaaaag cgtctcgaag ccgacaaaga cttctacgtc
    67861 tgtagcctgt cgaatctggt gaacatctat aaaggtctgt gtatgccgac ggatctgccg
    67921 cgcttttatc tggatcttgc ggacctgcgt ctggaatcgg ccatctgcct gttccaccag
    67981 cgcttctcca ctaacaccgt accgcgctgg ccgctggcgc agccgttccg ctacctggcg
    68041 cataacggtg aaatcaacac catcaccggt aaccgccaat gggcgcgtgc gcgtacctat
    68101 aaattccaga cgccgctgat ccctgatctg cacgacgccg caccgttcgt caacgaaacc
    68161 ggttctgact ccagttcgat ggataacatg ctggaactgc tgctggcagg cgggatggat
    68221 atcatccgcg ccatgcgtct attagtacca cccgcctggc agaacaaccc ggatatggac
    68281 ccggaactgc gtgccttctt tgactttaac tccatgcata tggagccgtg ggatggcccg
    68341 gcgggcatcg tgatgtccga tggtcgcttc gctgcctgta acctcgaccg taacggtctg
    68401 cgtccggcgc gctacgtcat caccaaagat aagctcatca cctgcgcctc tgaagtcggt
    68461 atctgggatt accagcctga cgaagtggtc gaaaaaggcc gcgtcgggcc aggcgaactg
    68521 atggttatcg acacccgcag tgggcgtatt ctgcactcgg cagaaaccga tgacgatctg
    68581 aaaagccgcc atccatataa agagtggatg gagaaaaacg tccgccgact ggtaccgttt
    68641 gaagatctgt ccgatgaaga agtgggtagc cgcgaactgg acgacgacac gcttgccagc
    68701 taccagaaac agtttaacta cagcgcggaa gagctggact ccgtaattcg cgtactgggc
    68761 gaaaacggtc aggaagcggt cggttcgatg ggcgatgata ccccattcgc cgtgctctcc
    68821 agtcagccgc gcattattta cgactacttc cgccagcagt ttgcccaggt gactaacccg
    68881 ccaatcgacc cgctgcgtga agcgcatgtt atgtcgctcg ccaccagtat cggtcgtgaa
    68941 atgaacgtct tttgcgaagc agagggccag gcgcaccgtt taagctttaa atcgccgatt
    69001 ctgctctact ccgatttcaa acagctcacg acgatgaaag aggagcacta ccgcgcagat
    69061 acgctggata tcacctttga cgtcactaaa accacgctcg aagcgacagt caaagagctg
    69121 tgcgacaaag ccgaaaaaat ggtacgtagc ggcaccgtgc tgctggtgct ctccgaccgg
    69181 aatatcgcta aagatcgcct gccggttcca gccccgatgg cggttggcgc gatccagacc
    69241 cgtctggtcg atcaaagcct gcgttgcgat gccaacatca tcgtcgaaac cgccagcgcc
    69301 cgcgatccgc accacttcgc cgtgttgctg ggcttcggcg cgacggctat ttatccatac
    69361 cttgcctatg aaacgctggg ccgcctggta gacacccatg cgattgccaa agattatcgt
    69421 accgtgatgc tcaactaccg taacggcatc aacaaaggct tgtacaaaat catgtccaaa
    69481 atgggcatct ccaccatcgc ctcttaccgc tgctcgaaac tgtttgaagc ggtcggtcta
    69541 cacgatgatg tagtgggcct gtgcttccag ggggcggtca gccgcattgg tggagcaagc
    69601 tttgaagact tccagcagga tctgctgaat ctgtcgaaac gtgcctggct ggcgcgtaag
    69661 cccatcagcc agggcggtct gctgaaatac gtccacggcg gcgaatacca cgcctacaac
    69721 ccggacgtgg tgcgcacgct gcaacaagcg gtacaaagcg gcgagtacag cgactatcag
    69781 gaatacgcga agctggttaa tgagcgtccg gcaaccacgc tgcgcgatct gctggcaatt
    69841 acgccgggtg aaaacgcggt caacattgct gatgttgaac cggcaagcga actgtttaaa
    69901 cgctttgata ccgccgcgat gtctatcggc gcgttaagcc cggaagccca cgaggcgctg
    69961 gcggaagcga tgaacagcat cggcggtaat tcgaactccg gtgaaggcgg cgaagacccg
    70021 gcgcgctacg gcaccaacaa agtgtcgcgc atcaagcagg tggcttccgg tcgctttggg
    70081 gttactccgg cgtatctggt caatgccgac gtcattcaga ttaaagtcgc ccagggcgcg
    70141 aagccaggcg aaggcggtca gttgccgggt gataaagtca cgccttacat cgccaaactg
    70201 cgctattcgg tgcccggagt gacgctgatc tccccgccgc cgcaccacga tatctactct
    70261 atcgaggact tagcgcagct cattttcgac ctcaagcagg ttaacccgaa agcgatgatc
    70321 tccgtgaagc tggtttccga accgggagta ggcaccatcg cgactggcgt ggcaaaagct
    70381 tatgcggact tgatcaccat cgcaggctat gacggcggca ccggcgcaag tccgctttca
    70441 tcggtgaaat acgcaggctg tccgtgggag ctggggcttg ttgaaaccca gcaggcgctg
    70501 gttgctaacg gcttgcgtca caagatccgt ttgcaggtcg atggcggcct gaaaacgggt
    70561 gtcgatatca tcaaggcggc gattctcggc gcagaaagct tcggcttcgg cactggcccg
    70621 atggtggcgc tcggctgtaa atatctacgt atttgccatc tgaacaactg cgcaacgggt
    70681 gtagcaactc aggatgacaa actgcgtaag aaccactatc acggcctgcc attcaaggtg
    70741 acgaattact ttgagtttat cgcccgtgaa acccgcgagc tgatggcaca gcttggcgta
    70801 acacgtctgg tggatctgat tggtcgcacc gacctgctga aagagctgga cggtttcacc
    70861 gccaaacagc agaagctggc gctgtcgaag ctgctggaga ctgccgaacc gcatccaggt
    70921 aaggcactct actgcaccga aaacaacccg ccgtttgata acggcctgct gaacgcgcag
    70981 ttgctgcaac aggcgaaacc gtttgtcgat gagcgccaga gcaaaacctt ctggttcgat
    71041 attcgcaaca ccgaccgttc tgtcggcgcg tcgctttcag gctatatcgc ccagacgcac
    71101 ggcgatcagg ggctggcagc cgatcctatc aaagcgtact tcaacggcac cgcaggccag
    71161 agtttcggtg tgtggaacgc gggcggcgtg gaactgtacc tgaccggtga tgccaacgac
    71221 tatgtcggta aaggcatggc gggcggctta atcgccattc gtcctccggt tggttccgcc
    71281 ttccgcagcc atgaagcaag cattatcggc aacacctgcc tgtatggcgc gaccggtggt
    71341 cgtctgtatg ccgcaggccg cgcgggtgaa cgtttcggcg tgcggaactc cggtgctatc
    71401 accgtggtag aaggcattgg cgacaacggc tgtgaatata tgacgggcgg tattgtctgt
    71461 attctgggta aaaccggcgt taacttcggc gcgggcatga ccggcggctt cgcttacgtt
    71521 ctcgatgaaa gcggcgattt ccgcaaacgc gttaacccgg aactggtcga ggtcttaagc
    71581 gttgacgatt tggcgatcca tgaagagcat ctgcgcggtc ttatcaccga gcatgttcag
    71641 cataccggtt ctcagcgcgg tgaagagatt ctggcgaact ggtcaacctt cgccacgaaa
    71701 ttcgcgctgg ttaaaccgaa gtccagtgat gtaaaagcac tgctgggtca ccgtagtcgt
    71761 agcgcagcag agttgcgcgt gcaggcgcag taaggggtag caacaatgag tcagaatgtt
    71821 tatcaattta tcgacctgca gcgcgttgat ccgccaaaga aaccgctgaa gatccgtaaa
    71881 attgagtttg ttgaaattta cgagccgttt tccgaaggcc aggccaaagc gcaggctgac
    71941 cgctgcctgt cgtgcggcaa cccatactgc gagtggaaat gcccggtaca caactacatc
    72001 ccaaactggc tgaagctcgc caacgagggg cgtatttttg aagcggcaga actgtcgcat
    72061 cagaccaata ccctgccgga agtttgcgga cgtgtctgcc cgcaagaccg tctgtgcgaa
    72121 ggttcctgca ccctgaacga tgagtttggc gcggtgacca tcggcaacat tgagcgttat
    72181 atcaatgata aagcgttcga aatgggctgg cgtccggata tgtccggcgt gaaacagacc
    72241 ggtaaaaaag tggcgattat cggcgcaggt ccggcaggtc tggcgtgtgc agatgtcctg
    72301 acgcgcaacg gcgtacaagc ggtcgtcttc gaccgtcacc cggaaattgg tggcttgctg
    72361 accttcggta ttccggcttt caaactggaa aaagaggtaa tgacgcgccg ccgtgaaatc
    72421 ttcaccggca tgggtattga attcaaactc aataccgaag tgggccgcga cgtgcagctg
    72481 gacgatctgc tgagtgatta cgatgccgtg ttccttggcg tcgggactta tcagtcaatg
    72541 cgcggcgggc tggaaaacga agacgccgat ggcgtgtacg cagcgctgcc gttccttatc
    72601 gccaacacca aacagttaat gggctttggt gaaacccgcg acgaaccgtt cgtcagcatg
    72661 gaaggcaaac gcgtggtggt ccttggcggt ggcgacactg cgatggactg cgtgcgtacg
    72721 tccgtgcgcc agggagcgaa gcacgttacc tgtgcctatc gtcgtgatga agagaacatg
    72781 ccgggttccc gccgcgaagt gaaaaacgcg cgggaagaag gcgtagagtt caaattcaac
    72841 gtccagccac tggggattga agtgaacggt aacggcaaag tcagcggcgt aaaaatggta
    72901 cgtaccgaaa tgggtgaacc ggatgccaaa ggccgtcgcc gcgcggagat cgttgcaggt
    72961 tccgaacata tcgttccggc agatgcggtg atcatggcgt ttggtttccg tccacacaac
    73021 atggaatggc tggcaaaaca cagcgtcgag ctggattccc aaggccgcat catcgccccg
    73081 gaaggcagcg acaacgcctt ccagaccagc aacccgaaaa tctttgctgg cggcgatatc
    73141 gtccgtggtt ccgatctggt ggtgaccgct attgccgaag gtcgtaaggc ggcagacggt
    73201 attatgaact ggctggaagt ttaagctctg tcccagcgcc gcctcctcag aaaagagtcg
    73261 gcgctgaaat tctcctttct ttctggaaag cgcctcgcat aatctgaaga aaaccaatgt
    73321 aatacgccca cctggattgt taccggtaga tgcccggcgt atagctgatt ccattattca
    73381 acgcagcgcc atataaaggg acagataatg gaatcgctct cagagagaac ctcaacaggc
    73441 taccagcaaa tccatgacgg tattattcac ctggtcgata gcgcccggac ggaaacggta
    73501 cgtagcgtta acgcgctgat gaccgcgaca tactgggaaa ttggccgacg aattgtcgaa
    73561 tttgaacaag gtggcgaggc cagggctgcg tatggtgcgc agctaatcaa gcgactatca
    73621 aaggatttaa gtctaaggta taagcgtggt ttctctgcaa aaaacttacg ccaaatgagg
    73681 cttttttacc tcttttttca acatgttgaa attcgccaga cagtgtctgg cgaattaaca
    73741 ccattgggaa ttccgcagac accatctgca gaattcccat cggcaaagat ttggcagacg
    73801 ctgtctgcca aattgagagg ctgtttgata tttccacagc ttttgtattg catctcctat
    73861 tttcggtttg tatattcatg caaataaacg aaggaaagtt gccatgattt acattgaaca
    73921 gcttgaatta atccataaaa gtggtgatgt gttgtatcca gtaaaaataa ccagaaaatc
    73981 atcaggaaaa actgccttcc accttgttcc attcggctta aataagactc acgaccttct
    74041 agaggtggaa gatgcttcag aagcaattcg gctggtgatt gatgaacgtc attccattcg
    74101 ctgcagtaca cttacagcaa ctattacgaa taaaaagggc aagcgaatta agcggacagg
    74161 tatatacagt atcaagggtg ttaacataaa agaatacaac gtcaggtaat ggcacagagc
    74221 ggtccgtcag ttcaggtttg gctctgtgcc aaagatgggt caggtcacac ctgatctaat
    74281 aaatttaagc cattaaatca gccttaacct tcaccaccac ctttttaatc tcacccggct
    74341 cgccaacaac gcatcccggc ttatgcggct ctcctggcat aaacacggcg aacattcccg
    74401 gttttaagat gatggcttgc tcgttatcaa tggtgctgca aagctgataa tcatcctcat
    74461 ggtggaactc ttcacactgg cgcgcagtgc ctgccatgcc aaacagaatc cgttcctcac
    74521 cgtttaataa cagttggata tcaatgtatt gctcgtgcaa ttccgctttt ttctcgacgg
    74581 gcgattgagt gttaaacgtc atgacattca taaagatatt gtcgccctgt aattcgtaac
    74641 gacccggcgc tttttcttgc ggtctggcag ctaatgccag cgttaacgcg tcctgtaacg
    74701 caggatgtaa cccagcagac ggtaatgact gtacttcacc catcatcata atttttctcc
    74761 ctgggccaac agcgcagccc caagtaaacc tgcatcgtgg cggtagtgcg ccgccagtaa
    74821 atcaacatga aatgccgctg gctcctgcgc cagatacgtt tccaccagcg ccagataccc
    74881 ttctgccagc ccaacgctgc caccgaccac cacgcactgg caatcagttg tggctttaat
    74941 atcagcgatc agccttgcaa gcgtacgtgc ggagcggtga atcagctgct gcgcctgctc
    75001 gtcgccctgc ccggcgcgtg tgaaaatagt tctcgcatcc gcgcccgcca gttcaccctg
    75061 cgctgccgcc gcaatgccgc gaccagaagc aatcgcctcc acgcaacctg tgcgtccaca
    75121 gccacagacc gggccgtgtg gatcggcaag cgtatgcccg atatgccccg ccagaccgcc
    75181 agggccggta agcagtttgc cgccgctcac tacaccgccg ccgacgccag tggaaacggt
    75241 gataaacacc atctcggtta catcgccttc cagcgcctga tactccgccc atgctgcagc
    75301 ctgcgcgtcg ttaatggcaa tggtcggcaa atcggtaagt tgttccagcg ttttgactaa
    75361 cggaaagtgt agcaatccac caagattatg cggattcagc gccagcaagc tgccgtcgcg
    75421 aataatcccg gttgaagcga tggcaacccg ctgcacatga gcttgcaacg gagagactaa
    75481 tgcggataag gcatcacgca aggcttctgg tgtctggctg gctggcgtag gaagttcacg
    75541 acgatcgcgg atctgcccgt cagcgccaat cagcgcggcg gcaagtttag taccgccgat
    75601 atcaatcgcc agcgtggtca tagcaccgcc tttttcatcg ctgtgttgta ccactgacaa
    75661 atgtgttcaa gacgcgtaat ggcagaaccg accgtcaccg cccacgcgcc gtggcgcatc
    75721 gcatctgccg cctgagcagg cgtgttgtaa cgcccttcgg caatcaccct acatccggcg
    75781 tcgctcaacg ttttcaccag cgccagatcc ggctcttctg gcgtttcagg cgtggtatag
    75841 ccagaaagcg tagtgccaat aatttcggct cccagctttt ggcatgccag gccgtcttcc
    75901 ggcgttgagc agtcggtcat cgccagtaaa ccgtgatggt gaatacgtgc cagcagcgtt
    75961 tcaacaggca ccggacgcgg gcggtcggtg ccgtcaatgg cgataatgtc cgcgcccgcc
    76021 tgcgccagcg catcaacatc ttcaatatag gccgtgatgc gtaccggaga atcctccaga
    76081 tcgcgtttca caattccaat aatcggcacg ctcaccaccg cacgcgtggc ttgcagattt
    76141 gccacacctt caatgcgaat ggcaaccgcg cccgcctgtt ctgccgctaa tgccatggcg
    76201 gcgacgattt cgggtttatc gagcgggctg tccggaaccg gctggcagga gacaatcagg
    76261 ccaccattag cagcgatttt ttgatccagt tgtgcaagta acgacataca tcttccctta
    76321 gcgaaaggcc cggtacatag aacgggcaac aggattaact tttggttttg actaaatcgt
    76381 ttttggcgct gccaaatggc acggcaccgc taaatggttt gccgtcgata gcgtcatgag
    76441 tacgcaatgc ttccgggcgc agccaacgct gaacgcggga aggcatatcc agaccaatca
    76501 gcaggatcac cacaaatgtc agactgaacg atagcgatgc cagcgcagta cccagatcca
    76561 gacgttgagc gatcaacgcg ccgatgattg gggccagtgc gccgcccaat gcgccaacgt
    76621 tgtaggtaaa gcccaggccc gctgcacgct ggtcggtatc gaaataaccg ccaatcagtt
    76681 tcggtaagat cccggcgatc ccttgtccaa gcatttgctg gaagaacagt aacagaccga
    76741 gcacccagac gtttgcgccg ccaatcgcaa ataccggaat aatcagcagc tgcgaggcca
    76801 gcaggctaca aacgtacgct ttgcgggttc ccagccagtc accgaggaag ccgccgacac
    76861 agcaccccac cgcagcccca aagccgctaa agaacagcac attggcgaca gtatgcgggt
    76921 tataagccag atcggttttc agatacgttg gcagcagcgc ctgaatcggc catgagtaga
    76981 ggaaagcaaa caacacgacc accatcagca ttacgcccgt tggccagcgt ttacccgtac
    77041 tttgcaccat aaagctgata aagattgcgg cgcataacag cccaagaaca gcgacgatcg
    77101 cggcattttg caggttaccg gcgaagcaaa accacagcgc agtagccgcc gccagtgtca
    77161 ttacgatatt ggcaatgcga tgttcaccac ggtagagaat atccaccatt gtgcgtactg
    77221 gtgctttacc tgcgtgtttc tctttccagt cttccgcttc cgggatgttt ttacgcagcc
    77281 agagagcaaa gatgattggc aaaatgccga taaagaacag cgcacgccaa ccccagaccg
    77341 gaaccaccag gctatagacc tgagcggcaa cgacggcccc cacagagaag cctgaaatca
    77401 aaaaaccact ggctttgtta cgcagatgtt ttggccagct ttcaatgaca taggtggcgc
    77461 tggaaccgta ttcacccgcc atccccatgc cgatgaccag acgagcgata aacatggtga
    77521 tgtagcctgg cgcaaagccg caggccagcg tcccggccga gaagagaacg atgctggtga
    77581 ccattgccag acgacgcccg tagcggtcac ccatagcgcc gagcatcagg ccgccgaacc
    77641 agcgagagat aaaggctgcg gagatcagac ttgccgcctg caccgtcgtc agcccgaatt
    77701 caccctgtac ttcggtgagt accagggcga ttaaaacgaa atcaaaaccg tcaagcagat
    77761 atcccaacca ggcagcggaa aatgcccgcc attgtgcacg attgagatgg cgataccacg
    77821 ggatattctg ggttgtagta ctcattgtga gtctcccgcg gtgggcgatg cccacacgct
    77881 ttggtatgaa aattgtaggg tacagatgcg tttatttccc ctcacccggt aggggcgagc
    77941 gaggggaaac aactcacccg cgctcttgca tcaactgctg ggccagcgcc ttcagttctg
    78001 gcagatattt ttcatctacc ggaccaaacg gtttgcggca cagcggcaca gaaacgacat
    78061 ccatataatg caggacagtt ttcaggccgc ggaatacgcc cgttttgatc agtaaatcaa
    78121 tgactttatt acattcggtt tgcagcttct gcgcggtctg gatatcgcct tctttcagcg
    78181 ccttcacaat cccctgataa cgccagccca tgatgttgta ggtactaccg ataccaccat
    78241 cagcgcccgc cagaagacca gaggcgaaga tttcgtcgta accgttatag agcaccagat
    78301 caggatgttc acgacggatc tgctccatct gatagagatc gccagaggtc tgtttcagcg
    78361 cacctacgcc aggcaacgta acaagtgtgt tgatctgatc cagggtcagt tttaccccac
    78421 tcagggctgg aatgttgtac accaccatcg gcaaaccatc cgccgaatca ataattgccc
    78481 gatagtgatc gcagtgttct tcaaagctga aaggatagta gaacggcgtg acggcggaga
    78541 cggcatcgaa gccataacgt ttagccgatg ccgcaagttg ttggctttcg gcggtgctga
    78601 cgcaaccgac gtgggcgatg agtttaatct gacctttcgc ctcttcggcg acgatttcca
    78661 gtacctgttc acgctcggaa aggctttgta caaaggcctc gccggtcgaa ccacccacgt
    78721 ataaaccgtc gatgccctgc tgaatattga actgaaccag gcgacgcaga ctcgctttat
    78781 ccagtgcttg ttgttggtca aaaggagtca ggagtgcagc cattacgcca cgtaaattcg
    78841 ttgccataaa tacctctgaa gtgatgcttg tctgataaac gatatacctt tatacctgtt
    78901 ataccagatc aattaagcaa caccccatac agaaagctta taatgcgatc tgcttcacta
    78961 aagtggcatt atttcttttt gttggtggtc tgaccgaagg cgtgccaggt agcagagacg
    79021 ctgttgagat gcgattgcaa cgcacgatcg gcttcgtcag gatcgtggcg gcggatcgcg
    79081 tcaacgatcg caatatgctg ttgatagcta acgttgttat gctcgtgcag agcctgatca
    79141 gccacggttg gacgtgcggc gattagccag tcgagcaggg caacgtggat cgccatgaag
    79201 attgggttac ctgggatctc cgccagcacg cggtggaaat caacgtctga acgaatgaat
    79261 gccgcgttgt tatccagcga ctgactgttg atttccagtg cttttgccag caaatcgatt
    79321 tgctcatcgg tggcgtgttc agccgcatag cgcaccaggc tggattcaaa gaacagacgt
    79381 aattgttcga aatgggcaat cccaccagga tgagaaagga aatctttcgc catgccggaa
    79441 agctcaccga tgatagtgtc cgcagaagga cgcgagacgc gagcgcgttc gccgttgttt
    79501 atttgcacca gacctttgcg ttttaacgct gccagcgctt cgcgcacaga aggacgcccg
    79561 acgttaaaga acgccatcag ttcgcgttca gacggtaatt gttcaccttc gccaaattca
    79621 cgacggcgga tcatctgttc cagctcttct tccaccattt cggagagttt tttacgcgcc
    79681 agcgggcggc tacgcaagtt gcgaccaatt gcaggtgaag aatcttcggt ttgcgaatca
    79741 aatgcgttca taaggcccat tctgtaaggt cagtgtgatt aacatcatca gtgacatcct
    79801 atcacaggat tgaaagtagg ggaaaatggc aggtttttct ctttgtgcct catcattacc
    79861 ataattaacg gaataattaa ctattgcgaa aaattaatgt aacgcagata aaaacatccc
    79921 gtttgaatta ttcataagac tattcacgag cattatgaat attatgaatg tgttcttaca
    79981 aaataatcat aagcgcatat tttttaatga aaaaccacct cacctacaat taaaaacacg
    80041 acatccgcac cataaataga cttgcaaaaa atataacatc attgttttca atctgccgtt
    80101 tatgggattg accgttttct tttgacacgg agttcaacaa tgttcggcat aattatatct
    80161 gtcatcgtat taattacgat gggctatttg atcctgaaaa actacaaacc tcaggtggtg
    80221 ctggctgccg caggtatctt cctgatgatg tgcggtgtct ggttagggtt cggtggtgta
    80281 ctcgatcccg ccaaaagcag cggctacttg atcgtcgata tttataatga aatcctgcgc
    80341 atgctgtcca accgcattgc cggattgggg ctgtcgatta tggcggtggg cggttatgcc
    80401 cgctacatgg agcgcatagg ggccagtcgc gcgatggtga gcttgttaag ccgcccgtta
    80461 aaactcattc gctcgccgta tattattctg tcggcaactt acgtcatcgg ccaaatcatg
    80521 gcgcagttta ttaccagcgc ctccggtctg ggtatgttgc tgatggtcac cttatttccg
    80581 acgctggtga gtctgggagt aagtcgtctc tctgcggtgg cagttatcgc aaccacgatg
    80641 tccattgagt gggggattct ggaaacgaac tccatttttg ctgcccaggt agcgggaatg
    80701 aaaattgcca catacttctt ccactaccag cttccggtcg cctcttgcgt cattatctcg
    80761 gtggcgatct cccacttttt cgtgcaacgc gcttttgaca aaaaagataa aaatatcaat
    80821 cacgaacagg cagagcaaaa agctctcgat aatgtcccgc cgctctatta cgccatttta
    80881 cctgtgatgc cgttaatctt gatgctcggc tcgctgttcc tcgcccacat cgggctgatg
    80941 cagtcagaac tgcatctggt ggtggtgatg ttactgagtt tgacggtgac gatgtttgtt
    81001 gagttcttcc gcaagcataa cttgcgcgaa acaatggacg atgtgcaggc gttttttgac
    81061 ggcatgggta cgcagtttgc caacgtggta acgctggtgg tcgcgggtga aatatttgcg
    81121 aaaggcttaa cgacgattgg cactgttgat gcggttatca ggggtgcgga gcattctggt
    81181 ctgggcggta ttggcgtgat gattattatg gcgctagtca ttgccatttg tgccattgtg
    81241 atgggctctg gcaatgcgcc gtttatgtca tttgccagtc ttattccgaa tatcgcagcc
    81301 ggactacatg taccagcggt tgtaatgatt atgccgatgc attttgccac gacgctagcg
    81361 cgcgcggttt cgccgattac tgcggtggtg gtcgttacgt caggaattgc aggcgtttcg
    81421 ccttttgcgg tggtgaagcg aacagcgatc cccatggcag tcggtttcgt ggtgaatatg
    81481 attgccacaa tcacgctatt ttattaagcc attaaaagac aaaacaggcc accagggcct
    81541 gtttttgtat tacttcacaa cgcgtaatgc cggtcgacca ccgcgtggtg gctgcggagg
    81601 ttcatcgtca ggatgagtgt catcatcgtg atctggcttg tcgccatcaa taaccgacat
    81661 aacggtttcg ttgtctgccg atgcctcttc atcattcatg atgctggtat cttcatcgta
    81721 ggcagcttca ggctcaaaca tcgtgcctgc gccattttca cgggcgtaga tagccagcac
    81781 ggcagccagc ggcacagaaa cctgacgcgg aatgccgcca aagcgcgcgt taaagcgtac
    81841 ctcatcattc gccagttcca gattgccgac agcacgcggc gcaatgttga gtacgatttg
    81901 cccgtcacgc gcatattcca taggaacctg cacgccaggg agcgtcacat ccaccaccaa
    81961 gtgcggcgtg agctggttat ccagcaacca ctcatagaat gcacgcagca gatagggacg
    82021 acgtggtgtt agctgtgaca aatccataca gattaactcc ggcccagacg catttcacgt
    82081 tctgcttcag ttaaagaagc aaggaaagag tcacgctcaa agacgcgggt catatagcct
    82141 ttcagctctt tcgcacccgg gccgctgaac tcgatgccca gttgcggcag acgccacagc
    82201 agcggagcaa gatagcaatc gaccaggctg aactcatcgc tcaggaagta cggcttctga
    82261 ccgaagaccg gcgcaatcgc cagcagttct tcgcgcagtt gcttacgtgc ggcatctgct
    82321 tcagaagctg aaccgttgat gatggtgttc atcagcgtgt accagtcttt ttcgatgcga
    82381 tgcatgtaca gacggctttc accgcgagct accgggtaaa caggcatcag tggcggatgc
    82441 gggaaacgct catccagata ttccataatg atgcgagatt cccacagggt cagctcacga
    82501 tccaccaggg tcggaacgct ctgattcggg ttgaggtcaa tcagatcctg aggcggattg
    82561 tccttttcca cgtgttcgat ctcgaaactt acacctttct cagccagcac aatgcggacc
    82621 tgatggctat agatgtcagt aggaccggaa aacagcgtca ttaccgaacg tttgttggca
    82681 gcgacagcca tgaaaacctc caggtatagt cagaattttt actgctacca gccaccaggt
    82741 ggccagtcag aagttgtgtt acccagtaag gaacgactct ctttgttcga aaatcaaaca
    82801 aaaaatgagc aatacccgac atttgggcag aaaattggat gatagtttac cagattttgc
    82861 gacctttgtg gtgagtcgat gccggaaatg gggaaaaaga gatgcgcttt agtctgaaat
    82921 agttgactta gtcccttatt ggcgatgtgg tttttgtttt gcctgtctgt cagacggtag
    82981 caaaaagcaa ctttccaatt tttacgctga ttcagaattt aaccataaaa aaacccgccg
    83041 aagcgggttt tttcgcaaat tgttttctgc cggagcagaa gccaattaac gtttggagaa
    83101 ctgcggacga cgacgtgctt tacgcagacc gactttctta cgttcaacct gacgagcgtc
    83161 acgagtaacg aagccagctt tacgcagttc agaacgcagg gactcgtcgt attccatcag
    83221 agcgcgggtg ataccgtgac ggatcgcacc agcctgacca gagataccac cacctttaac
    83281 ggtgatgtac aggtccagtt tctcaaccat gtcgaccagt tccagcggct gacgaactac
    83341 catgcgagca gtttcacgac cgaagtactg ttccagagaa cgttggttga ttacgatttt
    83401 accgttgccc ggtttgatga aaacgcgagc tgcggaactt ttgcggcgac cagtgccgta
    83461 gtattgattt tcagccattg cctataatcc cgattagatg tcaagaactt gcggttgctg
    83521 tgccgcgtgg ttgtgctcgt tacccgcgta aactttcagt ttacggaaca tagcacgacc
    83581 cagcgggcct tttggcaaca tgcctttaac cgcgatttca atcacacgct caggacggcg
    83641 agcaatcatc tcttcaaagg tcgcttgttt gataccaccg atgtggccgg tgtggtgata
    83701 gtacactttg tcagtacgct tgttgccggt tacagcaact ttgtcagcgt tcagaacgat
    83761 gatgtaatca ccggtatcta cgtgcggagt gtattccgct ttgtgcttac cgcgcaggcg
    83821 acgagccagt tcagtagcca gacggcccag agttttaccg gtcgcgtcaa caacatacca
    83881 gtcgcgtttt acggtttctg gtttagctgt aaaagttttc attaaaagct tacccaataa
    83941 atagttacac gttggtgaac acccaaacgt cttcaattgt tgaggttcac acgacaaagt
    84001 ccggcaaacc taccccttcg aatagcctat gccagcacac aaaaagtttt gggaaaaaaa
    84061 ctttcttgta acgtggggtc gcaggattat agagaagtcg gggtcaaaga tcgacccctt
    84121 tttgtgattt gtgacaggtt ttaacccgcc aaatgctcgc gcttcagata ctcttcgctt
    84181 tgcatctctt gcagacgtga caggcaacgc tggaactcaa acttcagccg atcgccctga
    84241 taaatttcat acagcggcac ttctgcactc accactaatt tgacatggcg ctcgtaaaac
    84301 tcatccacca gcgcaataaa gcgccgcgct tcgctctcca tcaaccgcgt cataactggt
    84361 acatcaaaca acatgaccgt atgaaagaga cgtgagagcg caatatagtc atgctgactg
    84421 cgggcgtcga cgcacagcgt agtaaaagag accgccagcg tctggttctc gacgcccatt
    84481 gtcgccaatg gccgatggtt gatttctaac gtcggtgaat tttctcgttt cgcccccgcc
    84541 agcgccaacc atagtttatc catctgcgcc cgggtttcat cgttgagtgg cgaaagccac
    84601 agatgcgcct gagtgagtgt acgcagtcga taatcaacac cagcgtccac gttcattaca
    84661 tcacaatgct gtttaatggc atcgattgca ggcagaaaac gcgcacgttg caggccattt
    84721 cgataaagtt cgtccggcgg aatatttgac gtcgctacca gggtaatacc gcgggtgaac
    84781 agggctttca tcagaccgcc aagtagcatg gcgtcggtaa tatcagaaac aaaaaattcg
    84841 tcaaaacaga gcacgtcagt ttcggcttta aagcgatcgg caataatttc cagcggatcg
    84901 gtctgcccct gtaaggcagt tagctcttca tgcacccgca gcataaaacg gtgaaagtgc
    84961 aggcgctgtt tccgctctcc cggcaggctt tgatagaaaa ggtccatcag ccaggttttc
    85021 ccgcgtccta caccgcccca catatataag ccacgcactg gcgtatgctt tgtgtcttcg
    85081 cgtttacccc acagcttacc gacccgcgcc attagcccac tcgtcctggg ggctggtggc
    85141 gtgctattga tgagttcctg ataaataatt tccaggcggc tgacggcctc tttttgaacg
    85201 tcgtcgggtt gatggctgcc ttcattaagc gccttcaggt attgcgatgt tggggtaacg
    85261 ctttgcatga tcttattgtt attccttgaa taatcggtgc gccgttgttc acggttgacg
    85321 aaaaaaaggc cgttctacac tacgcgatat gcagtcggga ttccacttct gtggaattaa
    85381 cggttatagt ggcataatca gccgcaggca tggagcctga agccaacacc ctacggaaac
    85441 aaaagacaac gggagatgtt catgacctgg gaatatgcgc taattgggtt agtcgtcggc
    85501 atcattattg gtgctgtggc catgcgtttt ggtaatcgta aactacgcca gcaacaggcg
    85561 ttgcagtacg aactggaaaa gaataaagct gaactggacg agtatcgcga agagctggtt
    85621 agccactttg cccgcagcgc ggaattactg gataccatgg cgcacgacta tcgccagctg
    85681 tatcagcaca tggcaaaaag ctccagcagc ctgctgccgg aactgtctgc tgaagcaaac
    85741 ccgttccgta atcgtctggc agagtctgaa gccagcaacg atcaggcacc ggtgcagatg
    85801 cctcgcgact attctgaagg cgcatccggc ctgctgcgta ctggcgcgaa gcgcgactaa
    85861 tttatttttc gggcgcagcc attgcgccct cctcttctct ccctccccga ctatcattta
    85921 atctggtgtc tcattgttag ccgtctgaaa attcaataac atcaaactgt tttgaatctc
    85981 ttttcttatc attcaggtac gagagcagga ataatgaaaa aacaaaccca gctgttgagt
    86041 gcattagcgt taagtgtcgg gttaactctc tcggcgtcat ttcaggccgt cgcgtcgatt
    86101 ccaggccagg ttgccgatca ggcccctctc cccagtctgg ctccaatgct ggaaaaagtg
    86161 cttccggcag tggtgagcgt acgggtggaa ggaacggcca gtcagggaca gaaaatcccg
    86221 gaagaattca aaaagttttt tggtgatgat ttaccggatc aacctgcaca acccttcgaa
    86281 ggtttaggct ccggtgtcat catcaacgcc agtaaaggct atgtgctgac caacaaccat
    86341 gtgattaatc aggcacagaa aatcagtatt cagctcaatg atgggcgcga gtttgatgca
    86401 aaactgattg gtagcgatga ccagagcgat atcgccctgt tacaaattca aaacccgagc
    86461 aaattaacgc aaatcgctat tgccgactcc gataaattgc gcgtcggtga ttttgccgta
    86521 gcggtcggta acccatttgg ccttgggcaa accgccacct ctggcattgt ttccgcatta
    86581 ggccgcagcg ggttgaatct tgaaggtctg gaaaacttta tccagacaga tgcttccatt
    86641 aaccgcggta actccggcgg tgcactatta aaccttaacg gtgagttaat tggcatcaac
    86701 actgcaatcc ttgcgcctgg cggcgggagc gtcgggattg gatttgccat ccccagtaat
    86761 atggcgcgaa cactggcgca gcagcttatc gactttggtg aaatcaaacg cggtttgtta
    86821 ggcatcaaag gcaccgagat gagtgccgat atcgccaaag ccttcaacct tgacgtgcag
    86881 cgtggcgcgt ttgtcagcga agtgttgcca ggttctggct cggcaaaagc gggcgtcaaa
    86941 gcgggcgata ttattaccag cctcaacggc aaaccgctga atagctttgc tgagttgcgc
    87001 tctcgtatcg cgaccaccga gccgggcacg aaagtgaagc ttggcctgct gcgtaacggc
    87061 aaaccactgg aagtagaagt gacgctcgat accagcacct cttcgtcggc cagcgctgaa
    87121 atgatcacgc cagcgctgga aggtgcaacg ttgagcgatg gtcagctaaa agatggcggc
    87181 aaaggtatta aaatcgatga agttgtcaaa ggaagcccag ctgctcaggc tggcttgcaa
    87241 aaagacgatg tgatcattgg cgtcaaccgc gatcgggtga actcgattgc tgaaatgcgt
    87301 aaagtgctgg cggcaaaacc ggccatcatc gccctgcaaa ttgtacgcgg caatgaaagc
    87361 atctatctgc tgatgcgtta atgtcgtaaa ccgggcatca ggcttacgtg tgatgtccgg
    87421 ttaactcgtg gtatgctgct gccgttccct tttttaatga cgcctccatc atgtttgtga
    87481 agctcttacg ttccgttgcg attggattaa ttgtcggcgc tattctgctg gttgccatgc
    87541 cttcgctgcg cagccttaac ccgctttcca ctccgcaatt tgacagtacc gatgagacgc
    87601 ctgccagcta taatctggcg gttcgccgcg ccgcgccagc ggtggttaac gtttacaacc
    87661 gtggtttgaa caccaactct cacaaccagc ttgagatccg caccctggga tccggtgtaa
    87721 tcatggatca acgcggttat atcatcacca ataaacacgt catcaacgac gccgatcaga
    87781 tcatcgtcgc cttacaggat ggacgtgtat ttgaagcatt gctggtggga tctgactctc
    87841 taaccgatct ggcggtactt aaaattaatg ccactggcgg tttacctacc attccaatta
    87901 atgcacgtcg cgtaccgcac attggcgacg tagtactggc gatcggtaac ccgtacaacc
    87961 tcgggcagac cattacccag gggattatta gtgccacggg tcgaatcggt ctgaacccga
    88021 ccgggcggca aaacttcctc caaaccgatg cttccattaa ccacggtaac tctggcggcg
    88081 cgctggtgaa ctcgctgggc gaactgatgg gcattaatac gctgtcgttt gataagagta
    88141 acgatggcga aacgccggaa ggtatcggct ttgcgattcc tttccagtta gcaaccaaaa
    88201 ttatggataa gctgatccgc gatggtcgcg tgatccgcgg ctacattggt atcggcggac
    88261 gtgagatcgc accactgcac gcgcagggcg gtggtataga tcaactgcaa gggatcgtgg
    88321 ttaatgaagt gtcacctgac ggcccggcgg cgaatgcggg tattcaggtc aacgatctga
    88381 ttatttcggt ggataacaaa ccggccatct ctgctctgga gacgatggat caggtggcgg
    88441 aaattcgccc tggttcggtg atccctgtag tagtgatgcg tgatgataag cagttaacgc
    88501 tgcaggtcac cattcaggaa tatccggcaa ccaattaagt cgtgcgctca aaacaaaaaa
    88561 ccggagtctg tgctccggtt ttttattatc cgctaatcaa ttacttatta acgaactctt
    88621 cgcccagggc gatatctttc ttcagcgtat ccagcatacc ttccagcgcg ttctgttcaa
    88681 atgcgctcag ggtaccgata gatttacgct cttccacgcc gtttttaccc agcagcagcg
    88741 gttgagagaa gaaacgggcg tactgaccgt cgccttcaac gtaggcacat tcgacaacgc
    88801 cttgttcgcc ctgcagtgca cgaaccagag acagaccaaa acgtgcagct gcctggccca
    88861 tagacagggt tgcagacccg ccaccggcct tcgcttcaac cacttcagta cccgcgttct
    88921 ggatgcgttt ggtcagatca gccacttcct gctcggtaaa actaacgcca ggaacctgtg
    88981 acagcagcgg cagaatggta acaccagagt gaccgccaat aaccggcact tcaacttcgc
    89041 ctggctgttt gcctttcagt tccgcaacaa aggtgttgga acgaatgata tccagcgtgg
    89101 taacgccgaa cagtttgttt ttgtcataaa caccggcttt tttcagcact tcagcagcaa
    89161 ttgcaactgt ggtgttaacc gggttagtga taataccaat gcacgctttc gggcaggttt
    89221 tcgcaacttg ctgtaccagg tttttcacga tgccggcgtt aacgttaaac aggtcggaac
    89281 gatccatacc cggtttacgc gctacgcctg cagagataag aacgacatct gcgccttcca
    89341 gcgccggagt cgcatcttca ccagaaaaac ctttgatttt cacagcagta gggatatggc
    89401 tcagatcgac agccacaccg ggagtcactg gagcgatatc atacagagag agttctgaac
    89461 ctgaaggcag ttgggttttt aacagtagtg caagcgcctg gccaataccg ccagcagcgc
    89521 cgaggactgc gactttcatc ctaaactcct tattatattg ataaactaag atatgttgct
    89581 ccgctgccgc gaccttaatc cacaaaattg ccgtttacaa tgaccacatc tcaagaatgt
    89641 gtagtcacgc aagtttagcg tttatgcatt taattgccgt aatcaggaac ctaacttacg
    89701 taattaacag tcgcttatgc attagcgcaa cattccaaca ggtggtgaca atatacccta
    89761 ccgttcagcc aaaacaacat caatttgata acaattaatt tacttttaag cagaatttgc
    89821 atgccgtgac gcaggcatgt ttctcaataa cgaaatttga taaaatcccg ctctttcata
    89881 acattatttc agccttcttc agggctgact gtttgcataa aaattcatct gtatgcacaa
    89941 taatgttgta tcaaccacca tatcgggtga cttatgcgaa gctcggctaa gcaagaagaa
    90001 ctagttaaag catttaaagc attacttaaa gaagagaaat ttagctccca gggcgaaatc
    90061 gtcgccgcgt tgcaggagca aggctttgac aatattaatc agtctaaagt ctcgcggatg
    90121 ttgaccaagt ttggtgctgt acgtacacgc aatgccaaaa tggaaatggt ttactgcctg
    90181 ccagctgaac tgggtgtacc aaccacctcc agtccattga agaatctggt gctggatatc
    90241 gactacaacg atgcagttgt cgtgattcat accagccctg gcgcggcgca gttaattgct
    90301 cgcctgctgg actcactggg caaagcagaa ggtattctgg gcaccatcgc tggcgatgac
    90361 accatcttta ccacccctgc taacggtttc acagtcaaag acctgtacga agcgatttta
    90421 gagctgttcg accaggagct ttaatctctg ccccgtcgtt tctgacggcg gggaaaatgt
    90481 tgcttatccc tctcaacccc ctgctttccc ctgcgattaa tttaacgaat agtgcgtttt
    90541 actgcgacat gtcattcaca caatgaatac ataaggtaaa aaaagcacat tatgcaaaat
    90601 tcattatcta attgaaaaaa ctagaattaa cgataaataa ccgtattttt aattcttttt
    90661 tgttattaaa attcacattt ttaacactta gtatcaactg aaacagttag cgcggtatta
    90721 attagctcaa taattagtgt atacttgatt ttgtgatatg ggtcacgaaa caaaggccca
    90781 gctaaaagat tatgtcgagg taaaaatcat gaaaatcaaa accactgttg ctgcattaag
    90841 cgtactttct gttctctctt tcggtgcatt cgctgccgac tccattgatg ctgcacaagc
    90901 acaaaatcgt gaagcaatcg ggaccgtatc cgtaagtggt gtggcgtctt cgccaatgga
    90961 tatgcgtgaa atgctgaaca aaaaagcgga agagaaaggc gcaacggcct accagattac
    91021 tgaagctcgt agcggtgaca cctggcacgc tacggctgaa ctgtacaaat aaaccctcat
    91081 cgtcttgtcc gacgatattg cccccggttc gggggctttt ttttgcgcta atgacgaaca
    91141 ttaaaacgca aatgcccttc cagctcttcc tctgcctcat caaacagcaa tattaacgcg
    91201 ccaaaacggc gacgcgtttt ctctcccaga tgaacaaatt caatctcaag tggtagcggc
    91261 aggacatcgt tcattaacac atcccatagt gagtcgagat cgcgtacctt atctttcgcc
    91321 agaccaaagg tttggctaaa gtcacgataa aaatcctcct gactctcaat ctcatcaaaa
    91381 tcaaaggtat aaatattcat ctgttgccac cgtcacgttt cgcggcgagt tctgccgtgc
    91441 atcgctaagt atagccatga aaaaaccgac gcttttggcg tcggttttga cttaactatc
    91501 ggtcaacgca tgttgatact tatggagcat ccccgccagc cgatttaccg gttccgtcac
    91561 ctgcggtggc gcttgccaga tgcgtagctt ttcctggtag atttccagtt cttccagcaa
    91621 ctggccaaag taccgacgac gtttatcatc gctacgggca gatatcacat ggtctgctgt
    91681 gcggcgcatt tgtcggtgaa acgccgataa atcctcgtta accgggatcg gtgcatcacg
    91741 caggcgctgg tgcgcgataa tcatcgtcag cgccaggcga aatttcggca aatcccctgg
    91801 gaacttattc atcagcaaaa acagctgctg ataaagtgcc gggaggtggt tctctttacg
    91861 acgtgccaca ttggtagtca tcgcggaaac agcggcagaa acaaactgat taagcagtac
    91921 acgtccggtc ctgtcgcgcg atttatcccg caccagcaaa ataacggtga acgcgagcac
    91981 acagccgacg atttgcccta atgcgctgtc gagaaactga ctgaaatgga aagtcatcgg
    92041 gttatccagc acgataatat ttatggtgct ggccagtgcc cccatcgagc ccagtcgccg
    92101 tttctgtact tctataccga ggaagaatcc cagcactgcc aggctaatgc acagcagcaa
    92161 catgctctgt tgggtattag ggataatcac caaaaagtag agcagcccta acggcagcgc
    92221 ggccagcgtc ccgtagataa agtcgatcgc caccatgcgt ggattcggca aacgcattgc
    92281 cagtgacgtc actaccgcaa tcatcaccat tgcaccactg ccggaagtcc agcccgtcca
    92341 cagccagaaa agcgtgccca gaatgcagga aagtgtggtt cgccagaagt taaccattgc
    92401 atgatgacgt tcggctgact ctacttttac ttccggttcg ccttgcagga tctcttcttc
    92461 ggtggcgttg atttttgtgt tactgataac gccgcgcttg agaagctgat aacgcgttgc
    92521 cgccgcgacc cagctataaa tggtgacagg cgtttcccgt tccccggtcc aggcgataac
    92581 tctccgcagg cgtttgagct gcttgtggac gtcctgcgcg gtttctaccg gcgtgtcaaa
    92641 aaattcgcgg aaagtatcag tgatcaattc cgggcgcgta ttctgaataa gataagtttc
    92701 gcaggattgg gtaatcagcg tcagcgatag cgtattgatc gcttttaaac gtcgattggc
    92761 ccgcgcccag cgggaagatt ccatattcag gttgctgcgc atgccttgta gcgccgtggt
    92821 gcgtcgcacc aggtcgcccc aggctttatc gacaacttca ccatcgccat gcttgataca
    92881 gagttgcatt aattgatatt gcgcgaccag caaactttcc agctctcgat ccacttcttg
    92941 tttgatcgat cgcggagaaa agagcaaatc cgccataatc gcacacacaa taccgataac
    93001 gatctcgcta caacgttcga cggcaaactg cggcgtaagc aatggttccg gctgaatggt
    93061 gatcacaatg atcagcgcgg tataaccggc cagcccccac gcatacgagt tttctattcg
    93121 taccagcgag gatatccagg tacaaaaacc ggcccagata cagcacacca gaatcatcaa
    93181 taatggtgcg cggatcatcg caatgatgat caccagtccg gcaatacagc caataaatgt
    93241 gccgatgatg cgcaaaaagc cacgatagcg aatagcgcca gaatacggtt cacctcccgc
    93301 agcaaaggcc ggaccggcgg caacaatcgc cgctgtcagt accgcccagc gtggcgtttc
    93361 cagctggaag tgaaagccaa caaacagcgc cagtacaatg gcggtcgcca gttttaccgc
    93421 aaagcgaata tgttggttag caatggagaa aatacccatc gtgattaacc aaactcacgc
    93481 aggcgatggg ccattttacg gaagaacgaa tcctggcttt cgtcgcgatc ttgtttgcca
    93541 gtgaccacca ctgtagcagt ggtgcccgca ggccagatgt tctcttgctg gttgtcgaga
    93601 cgaatacgaa ccggaacacg ttgcgcaaga cgcacccatt caaggttaga gtctatagtc
    93661 gccatccctt tgtcgtcacg cgtgctgctg gcgttggtga cccctgcggc aacactatca
    93721 acagtccctt tcagcacttt gttactgcca agcggcgtga tctctgcacg ataccccgga
    93781 cgcacccctt ccagcttagt ttcttccata taggccagta catagaagga gttctgtttc
    93841 accagcgcaa ccgccgttga tcctcgagta ataaactcac cggtatagac gttgaggttg
    93901 gtcacccagc catctgctgg cgcgcggatc accgtgcgtt caagatccag ttttgccaga
    93961 tcgcgggtcg cctgcgcttt cgctaactga tgcagaaccg tttgtagtac gttgttggcc
    94021 tggtcgatct cttcgcgaga catcgcctgc acaccgagac ggttacgacg tccggcctcc
    94081 tggcgtttct cctgtgccag tacctgataa taagcaacat cggcttgcgc ttcctcaagc
    94141 gccttttgat agcgcggctg gtcgatggtg aacagtatct gtcctttttt caccagctgg
    94201 ttatcatgaa cattcacctg ggtaatgagt ccagaaacgt ccggcgcgat cgcaacgacg
    94261 tcagcgctaa agcgcgcgtc acgcgtccag ggggattcgg tgtaatagac ccaggcatta
    94321 aaaattgcga tgaaggccag aatgactaat acgaccgtga tggccgtacg ggagaatttt
    94381 cttattagtg ttttcacttc aacctcaaac gaacagtcgc gatatcaaat aaaacaagca
    94441 gcaatagagc gcggtgttga acaacgccgg atgccagaca aagtcgtaga tacctgttgg
    94501 cacaagtacc cggcgcacca gccagaaaat cgccagtgat aaaagcaatt caaaaaatat
    94561 cggtgggaag gacagcccaa acaccacgat aacgggaaac agactcatgt tgaccttggt
    94621 tgtaaagaga gagcaggcgt tattattttc agcatctgtc gccgcagaga agggcatgga
    94681 aagccgggcg agagcaacat tgctgtagat tgatatttaa tatattagcg taactgttat
    94741 gctgttatct atattatgtg atctaaatca cttttaagtc agagtgaata atggaacgac
    94801 taaaacgcat gtcggtgttt gccaaagtag ttgaatttgg ctcttttacc gccgccgcca
    94861 gacagctaca gatgagcgtt tcgtccatca gtcagacggt atcaaaactg gaagatgagt
    94921 tgcaggtaaa gctgttaaac cgtagcacac gcagcattgg cctgaccgaa gccggtagaa
    94981 tttactacca gggctgccgt cgtatgcttc atgaagtgca ggatgttcat gagcaactgt
    95041 atgccttcaa taacaccccc atcgggacgc tacgcattgg ctgttcttca actatggcac
    95101 aaaatgttct cgccgggctg acagccaaaa tgctgaaaga atacccaggt ttgagcgtca
    95161 atctggttac cggaattcca gcccccgacc tgattgccga cggtctggat gtggtgatcc
    95221 gcgtcggcgc gttgcaggat tccagcctgt tttcccgccg tctgggcgcg atgccaatgg
    95281 tggtgtgcgc cgcgaaaagc tatctcacac aatacggcat accggaaaaa cccgccgatt
    95341 tgagtagtca ttcatggctt gaatacagcg tgcggcccga caatgaattt gaactgatcg
    95401 caccggaagg gatctcgact cgcctgatcc cacaaggaag atttgtgact aatgatccga
    95461 tgacgctggt gcgctggctg acggcgggtg ccgggatcgc ctacgtgccg ctgatgtggg
    95521 tgatcaacga gatcaatcgt ggggagctgg agatcctgct gccgcgttac cagtcagatc
    95581 cacgcccggt ttatgcgtta tataccgaaa aagataagct gccgctgaag gtacaggtcg
    95641 tgatcaactc gctgacggat tattttgttg aggtcggtaa attgtttcag gagatgcacg
    95701 ggcgcgggaa agagaagtaa ttcatattgt actgttacgt tgtacaaacc tgtgccaacg
    95761 ggttcccctc accctaaccc tcaccccaaa ggggcgaggg gaccgttcgt gcacgtagaa
    95821 agattaatta tccttctgaa aatagtgaaa ttattacgca gtaccgccaa cagtcaggtt
    95881 atcgactttc aacgttggct ggcccacgcc aaccggcaaa ctttgccctt ctttaccgca
    95941 gacacccacg ccgttatcca gtttcaggtc gttgccaacc atcgaaatct gctgcatggt
    96001 ttcgataccg gaaccaatca acgttgcgcc tttcaccggc ttcgttactt taccgttttc
    96061 aatcagatat gcttctgaag tggagaaaac gaatttgccg gaggtgatat ccacctgacc
    96121 gccaccaaag ttcggtgcat agataccgta ctcaacggat tcaataattt cctgcggggt
    96181 cgatttaccc ggcagcatat aggtgttggt catacgcggc atgggcagat gggcgtagga
    96241 ttcacggcga ccgttgccag tcggcgtcat ccccatcaaa cgcgcgttga gtttatcctg
    96301 catgtagcct ttcagaatgc cgttctcaat cagcacgttg tactggcctg gcgtaccttc
    96361 gtcatcaatc gccaccgaac ctcggcgatc gaccatcgtg ccatcatcaa ccacggtaca
    96421 cagttctgaa gccaccagct ccccgacctg tccactaaat actgaagtgc cacggcggtt
    96481 gaagtcgcct tccagaccgt gaccaaccgc ttcatgcaac agcacgcccg gccaacctgc
    96541 gccaagtact accggcatgg tgcccgctgg tgcagcaacg gcagaaagat tgaccagcgc
    96601 catacgcact gcttcttttg cccatgcatc cgcacggact tcgccgtcga gatcggcaag
    96661 gaagaattca taaccaaaac gaccgccgcc gccactggca ccgcgttcgc gtttgccatc
    96721 ttcttcgacg agaacgctca cggaaagacg caccagcgga cggacatccg ccgctagcgt
    96781 gccgtcggtg gccgcaacca aaattaattc atagacacca ctgaggctgg cagtcacttc
    96841 ctgtacgcgc ttgtccgctt cgcgggcaac cttatcgacg cgacgcagga tatccagctt
    96901 ctcttcacgg ctcatgcttt gcagcggatc taccgaggta tacaacgggc tatgctctac
    96961 cgcgcccagc gtctgtactt taccatcacc actatcacgg acgatggtgc gcgccgcttg
    97021 cgcactctgt tccagcgcca gcaggctgat ttggtcagcg taagcaaatc cggttttttc
    97081 accgctgatt gcacgcacac caacgccctg atcgatgttg taagaaccat ctttaataat
    97141 gcggtcttct aaaacccagg attcgtgata gctcgactga aaatagagat cgccataatc
    97201 aaggcgacgt tcggccagtt gaccgaggat cgcgaacaag tcctgatgtt tcaggccgtt
    97261 cgccgctagc aattgttcac ttaccaggtt aagactcatc gtttttgcta ctcgttagtt
    97321 actgcagtag aggatttttt acggctgccg gatgcggcgt gaacgcccta tccagcctac
    97381 ggttatgttc cggtttgtag gcctgataag acgcacagcg tcgcatcagg caacggctgt
    97441 cggatgcggc gtaaacgcct tatccgacct acggttatgt tccgtttgta ggcctgataa
    97501 gacgcacagc gtcgcatcag gcaacggctg ccggatgcgg cgtaaacgcc ttatccgacc
    97561 tacggttatg ttccgtttgt aggcctgata agacgcacag cgtcgcatca ggcaacggct
    97621 gccggatgcg gcgtgaacgc cctatccgac ctacggttat gttctggctc gttggccttt
    97681 ggcaacgatt atcctatgag attggggcaa ttacgcgccc tcgtcaaatc attgcgcttt
    97741 ttctttacgc ggttggcgca acacttcgtt gatttgcgga tcgtccagcg gacccgaaat
    97801 gtgatagcgc aaaatggaga ctttgctcca cagcggcccc agcactttac tggcggcaaa
    97861 cactgccgcg ccaacaatgg ggttaaccgc aaaagccgca gccacgccca ccgtcgcaga
    97921 aatctctggt gcgacaaccg cttccatatt caggtcgcga cgtaccagat ttaccgaccc
    97981 tttcatggcg atatccgcct ccaggccatc caccagcgtg tcgtcggtgt gcataacgcc
    98041 gtctttaatc cacgcggtgc tgcgaatgga gtcaaaatag aacccttcgc caaaagtgtc
    98101 tctgaaatca aaacgcagct tacgcatcag ggcatctacg ctcaataagc gcagcaattg
    98161 cccggcatgt ccggtattga tttcggtaat ttcgccttta cccagttgag tatgaatgat
    98221 gccattcaac gtcgcttcat ctggctgcca gggtgctttg cgccagtgta aatcgtaatc
    98281 cacattaaat gacgactggc gtatgggcgt cgtgacacca aaaaattctg cggcggcatc
    98341 aattttctgc ccgcgcagtt ttcctttcag cgaggtacgt tcattccccg gattattaac
    98401 ccattcacca tcggcagtaa gccgcgagaa accagtatca atcagtccat tggtcagcgt
    98461 taacgtatcg ccagaaatgg tgatatcact gtcaatgcga ccgaattttt gcccccagaa
    98521 ccagcactct gtgcatcgta tttgggcgtc cggccagcca cggaagttaa tgcgctccgt
    98581 tgtcgggaaa ggtgatgacg gcgttgaatc accacgagtt ttcgccacgc tcgggttgta
    98641 ataaagatat ttgatattcg ccagccacgg cgcgttatta cgcatcgcta gcgtggcgtt
    98701 gatttcacgc ccttgcgctt caaccagggt gccatttgcc gtcggttgcg aaacaatact
    98761 caggttattc cattgctgat ttcccagtga caacataggc gtacgtaacg ttatgtgttg
    98821 tgggaaactc gctgcaccac cgacactctc cgcagcgcct ttctggaaca gggccagcca
    98881 ctcggcacca ttcatcggcg gcatattgag ttcaacgcca ctttgttccg gcaacggcgg
    98941 gagcgtttta ctgtctgccg cccaaatagc acgatcgagc gtcagctttt gaccgagcaa
    99001 ccagcggcta ttgaaatgat tatccgcacc agcctgtccg gttaattcaa agctgttgag
    99061 attgccatca accttaacgt ttaccgctag tggttcaccc gcaggtttgg ctaacggtga
    99121 aggtaagtga ctgctcacat tctttagatc gccgttcagc tctatgttat aggtcgcacc
    99181 agcatgataa ggcagatcaa tgcccacttt accatcccac gccacgctgc cactcaatgc
    99241 ttcgttcacc gcttcaggca gaacgccggt tttcgccggt tgccagttac cgttgaggtt
    99301 taccgctacc tggtaggctt ttgccccttc tttggtggaa aaatccacgt tcaacggctg
    99361 attaaaccag cttgctgtca gtggttcact ttgcagatcg ctattgataa agctgaattt
    99421 accgctcaaa tttttcaggg tgctgtcgag tggtttgata aacagactgt tattacgcag
    99481 cgtcacttca cctttcgcgg ttaccagttc gccgttcagc gggatatcaa gatgtaagcg
    99541 agcattcaca tcgccgtcga gctggagttc ttgcagggtc gcacccagag aatctttcag
    99601 cggtgtctca tcaaagtaag ggccaacggc tttacccgga cctttaatgt cagcgtcaat
    99661 cagcagtttt tcttttgagt agtcagggat cactgcggta agattactcg cgcgcacgcc
    99721 gcccagatta acgccatcgg ttttcatcca taaaccgtcg ttaataaagt ccagttcaat
    99781 atcaaggtta gttaatgcag gccagtccgg ctggaaggca aacttcgcgt tgcgcagcgg
    99841 caccagcact tcaaactgac cttcgttgtg tttatagggg aagagttgcg gattgccacc
    99901 ataaaccagc gtcgcgttat ccgcttcacc gccctgaatc gcgccactta agtaatcaac
    99961 caggtcttta cccatcaagt tttccgggaa atagcgccag gcttgtgaac catcatcggt
   100021 actgatgcca gccagaatac ccagccaggg ttcatcgtta gcaggttgca ggtaacgaaa
   100081 accgccgcgc gcatggacgg ctttggcttt aacgtcaata ttacgcccat ccagctggaa
   100141 acctttgtta ttgttcagcc agcttatagt tgcctggccg tcggcgattt ctagtggcgc
   100201 acggaatacc gtttcgtaag gcatctttgc ctgcttcatc gacgcggtaa gcaaaccatt
   100261 ttcaacgctg ccggaaagcg tcccggagaa gtgttccgca cccggtaata atttccattg
   100321 cttccaggcc agatcgctcc acgatgcctg aaaacgggtc ttgtctgccg cctgaagcgg
   100381 gatatccagc gccagagtgt taatcttgcc gctcggttgt gtggagcgcc aaacatcacc
   100441 cagtgcaggt gaaagtttcg cggccagcgg gcgtatgccc tccaggcctg ccagctccag
   100501 attactggcg cgaatccgga gttcgtcact gcgtttattg tctttgccgc caacgtcctg
   100561 ttccggtatc caggccagcg tcaatgctcc gctcggccag ggtttgccgt ccatcgtgat
   100621 ccgtgtatcg ggaatagaga actgccagcc cggattttca cgcgtaatat gcgcggtcag
   100681 attatccacc gacagcgtat gcgtttgctt ctcgcccaac cagctggcac cgccctgttt
   100741 cagccagacg tcaccgccgg ttacatcgcc tttgtcgatc gtcatccagc cttcaaggga
   100801 gaactgtgcc gtttccagcg caatattgtc ctgcatccat ttaccgagcc acggcttcag
   100861 gtcgatgtca tccgcctgga gccagacgcg accattgctt aacaacccct catcatcgcg
   100921 caaatccatg cgcacctgca tcacgccgtg ctgtccggta aggctggaga ggcttaccag
   100981 gccttccgca cggtgtcgac gtggatcgtt cagccaggtg agttgtggga tcgccagctc
   101041 ggcgcgctga ccggatggcg tcaggaaact gacttcactg tcgcgaagat cgaaatggtc
   101101 aaattgacga agaaacagat cgctgatgtg actggcttcc agactgtcat cactaccacc
   101161 gctggtgata ggagtgttgg tgcgaaagcg cagctgccag aaagtgaggt cgcgaaactg
   101221 ccagcgcata tgtaacaggc tctgccagac atccagcgcc agagtaacgc gtttaaccga
   101281 aaattcgccg ccatctttta gttctgcacg gatgtcgtgt gcttcaagcg tcgggccaaa
   101341 attctgccag ctggctgaga gctgactggc ttctaccggc atgccagtcg cggattctat
   101401 tttgttgagg atttccggac gccaggcgtc aagatgcggt aaagcaatac gcaggccgct
   101461 aaccagcagg gcagcgatca caacgagcgc ggctccagta agcagtaaaa tccccggcaa
   101521 tcgcctcacc cgtcactcct tgtctgctaa aaatgtgact caaaaaccct ttgccggatg
   101581 gcggcccagc atctgtttac atcattacga cgtcaaactg ctcctggtta tagagcggtt
   101641 caatttgtac tttaacctgt ttgccaacga aaatttccac ttccgccagc gagtgtgact
   101701 cttcgccttt caaggcttca gctactgccg gagaagcata gaccaggaaa cggtcggagt
   101761 cgtaagcatg gtggacacga acaatctcgc gcatgatttc atagcatacc gtttccacgg
   101821 ttttcaccgt tccgcgaccg tggcaggttg ggcattcgtt acacagtacg tgctcaatgc
   101881 tttcgcgggt gcgtttacgc gtcatctcca ccagccccag cgccgaaaaa ccattaacgc
   101941 tggttttcac ccggtctttg ctcaacgcct gctccagcga gtgcagcact cggcggcggt
   102001 gatcttcatt attcatatcg atgaaatcaa taatgataat cccgcccaga ttacgcaacc
   102061 gtaactggcg agcgatagcc tgcgtcgctt caatattggt attgaaaatg gtgtcgtcca
   102121 gattgcgatg accgacaaac gctccggtat tgatgtccac ggtggtcatc gcttcggtct
   102181 ggtcgataat gagataacca ccggatttca gttctacttt gcgttccagc gctcgctgga
   102241 tttcgttttc gacatcaaag agatcgaaaa tcggctggcg tcctgtgtaa tgctccagct
   102301 tgcttgtcat ctcgggaatg tactccgagg tgaactcaag taacgcttcg taagtcaggc
   102361 gtgagtcaac gcgaatgcgg tccagttcgg catcggcgaa atcacgcaga acacgctgcg
   102421 ccagcgccag ttcgccgtac agctgataac gggtctgcgg gcgtttttta cgctccataa
   102481 ctttggtcca gacgcgtttc agataagcgg catcggaggc cagttcagcc tcgccaaccc
   102541 cttccgctgc ggtacggatg ataaacccgc cctgctcgtc gcaatactct gcgaccactt
   102601 ttttcaggcg ttcacgttct gattcgcttt caatacgttg ggaaacccca acgtgagaag
   102661 cccctggcat aaacaccaga tagcgagaag ggagcgtgat atcggtggtc aggcgcgcac
   102721 ctttagtgcc aagcggatct ttcaccacct gcaccatcag atcttgcccc tgacgaacca
   102781 gttccgagat gtcgcgcacc gtgaattgct tttgttcttc acccgccaca cattcggtgt
   102841 gcggcatgat gtcggatgca tgaagaaacg cggctttatc cagcccaata tctacaaaag
   102901 ccgcctgcat acccggaagt acacgactta cacgaccctt gtagatattg cctactattc
   102961 cgcgtcgcgc ctcacgttca atatgaattt cctgcagaat accgccatca atatacgcca
   103021 ctcgcgtttc cgaaggcgtt acgtttacta acaattcagc cgtcatgttt atcccttttc
   103081 tcacgcagtg cgttaaaatt acttaataat tcatacgttt caaccagcgg taagccgact
   103141 acggcgtgat agctgccatt tatcttcctg acaaaacagc cacccagccc ctgaataccg
   103201 tatgcacctg ctttatctaa cggttcatcg ctggcgacat agcccgcgat gtcttcgtct
   103261 gttaacgttc tgaaagtcac atcggtgacc accaggcaat cgagaatgtg ctggctgtcg
   103321 gccaacgcca ctgctgtcat cacctgatgg gtctgacccg ataatttgcg caacatctgc
   103381 gccgcatgct ctgcgtcgcg cggtttctcc agcacttctc cgttcaggat aacgatagta
   103441 tccgcaccca gcaccgggag atccttcgcc gtttgcgcga cacctgcccg tgctttctcg
   103501 cgcgccagac gcacaacata ctgctgcgcg ctctcctgcg gctgacgctg ctcctcaatg
   103561 cccgtaacaa tacgttcaaa ggtcacgcca agttgcgcaa gtaactcctg acgacgcgga
   103621 gaaccggaag ctaaatacag agaagtcata gaaaccttta ttgcactgca aactgctgac
   103681 ggactttgcg catcagcaag aaaatccacg gccagagcac cccattgact acactactcc
   103741 agaacacttc cggtctgaaa gagacgttaa tcactaaaaa ctctgcccag aaaacaataa
   103801 tatccaccac cagcgaaagc aacatgacga ccagcgcctg ctgccataat gcgaggttgc
   103861 ggaaaagctg gtatttcagc gccaccaggt aagcaatgat gctcatcgcc aatacgcgta
   103921 cgccaagcgt cgagccgctg atcagatcca gtatggcacc catcacaaaa cctgtgccca
   103981 catttacgcg atgaggcaag gccaggatcc aatacaacaa gatgagtaac acccagtttg
   104041 gccggaaaac aatcaggtta tccggccagg gcatgatttg cagcaacagc gcaatgagga
   104101 aagagagcca gattacccag cgtccctggc tacgatagct cgccactatt gccctcccgg
   104161 cgcacgcgca ggcggttgag caccactttg cggcggcgta gccctttgtg gagagcgatt
   104221 agcagcaggc tgtgtcggcg cagcaggcgc agtagctgca tttcctgtcg ccggttgctg
   104281 cggagtcggc tgagcgatcc ccgttgccgg ttcaggtaac tttggcccca tcgcgtctgg
   104341 cgaaggcaat acctgcggca tcatctgcat cagacgttca ttagcaacac gatgcacctc
   104401 ttccggcgtc atcgggttag cgccgttacg atctgccccc cacagcagca gcagataacg
   104461 caaacgttgc agccctgcag tcggacgcgc ctgaatcaca gtataagcgc gctgggtatc
   104521 gagttttacg gaagagacaa ccgcgaccgg atagccttcc gggaaacgac cgcccagacc
   104581 ggaagtcacc agcacatcac caacacgaat atccgtattc gccggcagat gctcaagctg
   104641 caaatcatcc gtacaaccgt taccggctgc aattacgcgg atatcgttgc gcagcacctg
   104701 gattggcagc gcgtgggtcg catcacaaat cagcagcacg cgactggtca gtttagcgac
   104761 ggccaccacc tgaccaacaa cacctttgtc gctgatgacc ggctggcctt cataaacgcc
   104821 attaacgcta cctttatcga taacaacttg atcgctataa ggatcgttaa ccgtggagat
   104881 aacctgagtc accattttct gctcatcctg acgcagcggg gaacccagca gctcgcgcag
   104941 acgcgcgttc tcctgtttgt attgtccaag catcagcagt tcactgtttt tcagcaacag
   105001 ttcctgacgt aacgcccggt tttcaagttc taattggtca cgcgaggcca gcgtctgcga
   105061 tacgccatcc agcaattcac gaggagcatt ggaaacaaag tagaaaggac tgacggcggt
   105121 atccatataa gtacggattt gactgaacgt ccccaggcgg ctgtcggcaa taataatgcc
   105181 gagcgccacc agcaccgcca gaataaggcg aatctgtagc gacgggccac ggctaaaaat
   105241 tggcttcata agttatgcgt attctcgtat cagaccaggc agggtaaaca gacacttccc
   105301 ctgcctgcat ccgattactc ttcgctgaac aggtcgccgc cgtgcatgtc gatcatttcc
   105361 agcgctttgc cgccaccgcg cgccacacag gtcagcgggt cttcagcaac aacgactgga
   105421 atgccggttt cttccattaa caaacggtca aggttacgca gcagtgcgcc accaccggtg
   105481 agcaccatgc cgcgctcgga gatgtcggaa gccagttccg gcgggcactg ttccagtgca
   105541 accattaccg cgctcacaat accggtcagc ggttcctgca gtgcttcgag gatttcattg
   105601 gagttcaggg taaaaccgcg tggaacacct tctgccaggt tacggccacg aacttcgatt
   105661 tcacggactt catcgcccgg ataagccgaa ccgatttcgt gcttgatacg ttctgcggtg
   105721 gcttcaccga tcagagaacc gtaattacga cgcacatagt tgatgatagc ttcgtcgaaa
   105781 cggtcaccac caatgcgcac agaagaggag taaaccacac cgttcaagga gataacagca
   105841 acttcagtgg taccaccacc gatatcaacc accatagaac cggtcgcttc agaaaccggc
   105901 aggccagcac caattgcggc agccatcggt tcttcaatca ggaagacttc acgggcacca
   105961 gcgccctgcg cggattcacg aattgcgcgg cgttcaacct gggtcgcgcc aaccggcaca
   106021 caaaccagaa cgcgcgggct tggacgcata aagctgttgc tgtgcacttg tttgatgaag
   106081 tgctggagca ttttttcagt cacgaagaag tcggcgataa cgccgtcttt cattgggcga
   106141 atggcagcaa tattgcccgg cgtacggccc agcatctgct tcgcgtcatg acctactgca
   106201 gctacgcttt tcggtgaacc ggcacgatcc tgacgaatgg ccaccacgga aggctcattc
   106261 aatacgatgc cttgtccttt tacataaatg agggtattcg cagtacccag gtcaatggac
   106321 aagtcattgg aaaacatgcc acgaaatttt ttcaacatac taagggataa tcctgaaagc
   106381 tggggcggaa aagaaaatcc gcttacttta ccaaccacac gcagcagcga caaggcgcaa
   106441 aaatcatctg ctacggtgaa aattagtgca gttcgtttcc tttgttacaa atctctgcct
   106501 gagtccagaa aggcttaatg catcagcagc attcctcgcc tgtttgcaac cgcgtaaggt
   106561 cattcatctg catatgtgct gcaacaatct ggcgagcaga caagcacact cccatgagac
   106621 gcagcgcgcg ttattctacg tgaaaacgga ttaaacggca ggttaaaccg agtatctttg
   106681 tgaatatttt ttcacgttag tatcaagtgg ctgtgaggac gcgaaaaaat ccccttgccc
   106741 gcctgtaaca ccgcgctgaa tcagggtctg ccactcgctt cgcgaacgca cgccggtggc
   106801 gtaaacctgg gtgctggtcc cggagcaggc ttccaccagg ctttgaacca gcagctggtt
   106861 ctccgttcgc ttctcaatgt ttctgaccag ccccggatgg agcttgagta actcaacatt
   106921 aagttctttg atccaactgg tgcttaccag cgtcaaacca gcctggttga cggctacccg
   106981 tacccctaaa gcattcacta aacgaataac aggttgtaaa cgactgatat gttgacctac
   107041 atcggcctct gcaagttcaa taattatgcg ttttcgttgt gatttttcac attgcattaa
   107101 cgtatcgcgc agccaacgct gaaaacgcgg gcgaatcagc gactcaacgg taacctgaat
   107161 cgccagattt tcctctggcc agtaacgcaa tagtggaata agacggctga tttgcagacg
   107221 gtcatactct tccgataagc caaactgcaa gaccatcggc atatactccg ccgagctaac
   107281 ctcttcatta ccatcgaaga tgcggcacat gagttcgcga tgatgaacct gaccttcgca
   107341 agtaaccgcc ggtttttgat aaaggcgcgg gccgccgcga ctgagcattt gctcgataag
   107401 cgtacgccag cgaacattac cgcgtccttt ttcaggcaac gagtcatcgt aaatagccca
   107461 gctattgccg ccctgcaatc ccgcattacg cgtggcagac tctgcatgtt ccattacctg
   107521 ctcggtatcc tgaccactac gccaggcgca gataccaatg tggatcatat cgtcgcgatc
   107581 gagcatttta ttgttcggca aggtatcgac ggctttgatt aactgaccgg cgatgctctc
   107641 tgcctctttt aacgtccggt gcggtaacag cgcagcaaaa tcactgcggt ggtaacgcgc
   107701 cagcagtgcg ccagggtagc gcatcataaa tgtcgacagc agattcgtca gagtgaagaa
   107761 ctgttcttca acctggctgt gcccccaggt atcgctcaac atattgaaat ccggcagacg
   107821 aatcatcatc acgatcccgt gggtacctac tttctcctga tcttccagta acgttgctaa
   107881 ctgattatcg aaaaagagtc ggttattgag gccggttttc acgtcctggg cggcataaga
   107941 gcggatcagc gtatcaagac ggctgtgttg ttcgcgtgcg ttctgaattt cacgaagcag
   108001 cgtatctagc gcactgctgg ttctgggcgg ccattcatag atggttccca acacattaga
   108061 gccacgctca ccgtttaaga tacgagtagc ccgggtttcc agcaattctt gcccggcaag
   108121 ttgccgttgt aaccagcgta ccgccaggaa gagcataaca atgataaagc caatcgcccc
   108181 cgtgagcggc gcggtagtca ttaaagaatg gaaatagttg cccatcggat cctgataaac
   108241 cagacgcagc gacatccccg gatgctttat caacggaaca ctcagttcgc gaaacagatc
   108301 gctggagcca accggacgat aactaccatt tctggccagg gtataaacct gtttatcacc
   108361 atggagcagg tctacacgaa cgatatctgc cgacatcatt aattcggtaa tttgtggcct
   108421 taatgtgctg aagtcattcg acacaaggtg ggtatcaatc gccgtcgcca ccgcctgaac
   108481 gcgatgacta aacttatact gaattgcgtt gtagaaactt agcgaacagc ccagcaaagt
   108541 cacaaaaatt gttaacccgg tgagcagcgt aacaaaggcc gaaaatttcg tcgttaatct
   108601 catccttgtg ttaactccga tagtgaggaa gcgggcatac tagcaaatca gatttatctc
   108661 gcaatttatt gcgcttcatc ggctttgctt ttccattagc gagtatagtc ttcagaaatt
   108721 attttccaat ccatcatgca catgaggacc acttatgcag gcgttacttt tagaacagca
   108781 ggacggcaaa actctcgcat cagtacagac tctggacgaa agtcgcctgc cggagggcga
   108841 tgtcacggtc gatgttcact ggtcgagcct gaactataaa gatgcgctgg cgattaccgg
   108901 taagggaaaa atcatccgta attttccgat gattcctggg atcgattttg ccggaactgt
   108961 acgcaccagc gaagatccgc gttttcatgc cggtcaggag gtgttactca ctggctgggg
   109021 cgttggtgaa aaccactggg gtgggctggc ggagcaggcg cgagtgaaag gtgactggct
   109081 ggttgccatg ccgcaagggc tggacgcgcg taaagcaatg attatcggta ctgccggttt
   109141 taccgccatg ctgtgtgtga tggcgctgga agatgccggt gttcgcccgc aggacgggga
   109201 gattgtcgtg acgggtgcca gtggtggcgt cggcagtacc gccgtggcgc tgctgcataa
   109261 gttgggttat caggtcgttg ccgtttccgg tcgcgaaagt acccatgaat atctgaaaag
   109321 tttaggtgct agccgtgttc tccctcgtga tgagtttgcc gaatcccgtc ctctggaaaa
   109381 acaagtctgg gctggggcaa ttgacaccgt tggcgacaaa gtgctggcaa aagtgctggc
   109441 gcaaatgaat tacggcggct gcgtggcggc ctgtggtctg gcgggtggtt ttactctgcc
   109501 aaccacggtc atgccattta ttctgcgtaa tgtccgtttg caaggggtgg attcagtaat
   109561 gacgccacca gaacgccgcg cacaagcctg gcagcgactg gtcgccgatt taccggaatc
   109621 attctatacc caggcggcaa aagagatatc tctgtcagag gcaccgaact ttgccgaggc
   109681 catcattaat aaccagatcc agggtcgcac gctggtgaag gttaactaac catttagcag
   109741 ggaataataa gagagggaac tcattttgaa atcattattc aatcggttaa cgggaaaagc
   109801 ggttagccgg acagctttcg tcgaacacct tggtcaggaa gttatacaac atcatccaaa
   109861 ctggaaagtc atgatttcga ctgaccacaa attgatgcgc attgatactc cactaaacag
   109921 ctattattga tacgcctccg tcgcctgtta ggtttatggt gctttgcctg ggcgacgcta
   109981 cgcttagccc cttacttatt tctggtacca tggggtgaat aatctgattt tgtttgacta
   110041 caaattaatc actcgaacct atttaatgct gagcattgtc aatcggttaa ttttgcgtgc
   110101 tttagcattc acatctatcc agacgatgca gtgaaaattg ggtaatcccc agcaaccgct
   110161 gcgtaatgtc gtctatcttg tcgcgatcct ggcatcccta cattatttgt ggtctgtgaa
   110221 gattatctca ttgcagcccc tcatcttcgc agggctggct tttcagcttt tcaccttacg
   110281 ttataagaag ttccgtcgat gatggcgcta atttcgtgaa ttgtgcggct tgttgcaaat
   110341 tacacggtgt tgaaggttat ttacatgtta gctgttgatt atcttccctg ataagaccag
   110401 tatttagctg ccaattgcta cgaaatcgtt ataatgtgcg acctcgtcct ccctgacgca
   110461 gtttttgcac tgcggaaaag gtgacattgg cgcaacgaag gtatattttg ttttttgccg
   110521 gaggatagca gcagatcgct gcacaatgtc cgtcaagtct aacattgaca ctctggggca
   110581 aaatagaccg gcgtcccggc ctgctggaat ttatcgctat gcatacagct gtcggggcat
   110641 acgctttaca gacggcggtg aaacgcctgt cacaatcaca ctaaacaaag agtacggaac
   110701 ccactcatgg atattcgtaa gattaaaaaa ctgatcgagc tggttgaaga atcaggcatc
   110761 tccgaactgg aaatttctga aggcgaagag tcagtacgca ttagccgtgc agctcctgcc
   110821 gcaagtttcc ctgtgatgca acaagcttac gctgcaccaa tgatgcagca gccagctcaa
   110881 tctaacgcag ccgctccggc gaccgttcct tccatggaag cgccagcagc agcggaaatc
   110941 agtggtcaca tcgtacgttc cccgatggtt ggtactttct accgcacccc aagcccggac
   111001 gcaaaagcgt tcatcgaagt gggtcagaaa gtcaacgtgg gcgataccct gtgcatcgtt
   111061 gaagccatga aaatgatgaa ccagatcgaa gcggacaaat ccggtaccgt gaaagcaatt
   111121 ctggtcgaaa gtggacaacc ggtagaattt gacgagccgc tggtcgtcat cgagtaacga
   111181 ggcgaacatg ctggataaaa ttgttattgc caaccgcggc gagattgcat tgcgtattct
   111241 tcgtgcctgt aaagaactgg gcatcaagac tgtcgctgtg cactccagcg cggatcgcga
   111301 tctaaaacac gtattactgg cagatgaaac ggtctgtatt ggccctgctc cgtcagtaaa
   111361 aagttatctg aacatcccgg caatcatcag cgccgctgaa atcaccggcg cagtagcaat
   111421 ccatccgggt tacggcttcc tctccgagaa cgccaacttt gccgagcagg ttgaacgctc
   111481 cggctttatc ttcattggcc cgaaagcaga aaccattcgc ctgatgggcg acaaagtatc
   111541 cgcaatcgcg gcgatgaaaa aagcgggcgt cccttgcgta ccgggttctg acggcccgct
   111601 gggcgacgat atggataaaa accgtgccat tgctaaacgc attggttatc cggtgattat
   111661 caaagcctcc ggcggcggcg gcggtcgcgg tatgcgcgta gtgcgcggcg acgctgaact
   111721 ggcacaatcc atctccatga cccgtgcgga agcgaaagct gctttcagca acgatatggt
   111781 ttacatggag aaatacctgg aaaatcctcg ccacgtcgag attcaggtac tggctgacgg
   111841 tcagggcaac gctatctatc tggcggaacg tgactgctcc atgcaacgcc gccaccagaa
   111901 agtggtcgaa gaagcgccag caccgggcat taccccggaa ctgcgtcgct acatcggcga
   111961 acgttgcgct aaagcgtgtg ttgatatcgg ctatcgcggt gcaggtactt tcgagttcct
   112021 gttcgaaaac ggcgagttct atttcatcga aatgaacacc cgtattcagg tagaacaccc
   112081 ggttacagaa atgatcaccg gcgttgacct gatcaaagaa cagctgcgta tcgctgccgg
   112141 tcaaccgctg tcgatcaagc aagaagaagt tcacgttcgc ggccatgcgg tggaatgtcg
   112201 tatcaacgcc gaagatccga acaccttcct gccaagtccg ggcaaaatca cccgtttcca
   112261 cgcacctggc ggttttggcg tacgttggga gtctcatatc tacgcgggct acaccgtacc
   112321 gccgtactat gactcaatga tcggtaagct gatttgctac ggtgaaaacc gtgacgtggc
   112381 gattgcccgc atgaagaatg cgctgcagga gctgatcatc gacggtatca aaaccaacgt
   112441 tgatctgcag atccgcatca tgaatgacga gaacttccag catggtggca ctaacatcca
   112501 ctatctggag aaaaaactcg gtcttcagga aaaataagac tgctaaagcg tcaaaaggcc
   112561 ggattttccg gcctttttta ttactgggga tcgacaaccc ccataaggta caatccccgc
   112621 tttcttcacc catcagggac aaaaaatgga cactcgtttt gttcaggccc ataaagaggc
   112681 gcgctgggcg ctggggctga cccttttgta tctggcagtt tggttagtag ccgcttactt
   112741 atctggcgtt gcccccggtt ttaccggctt tccgcgctgg tttgagatgg cctgcatcct
   112801 gacgccgctg ctgtttattg gactgtgctg ggcgatggtg aaatttatct atcgcgatat
   112861 cccactggag gatgacgatg cagcttgaag taattctacc gctggtcgcc tatctggtgg
   112921 tggtgttcgg tatctcggtt tatgcgatgc gtaaacggag caccggcacc ttccttaatg
   112981 agtatttcct cggcagccgc tctatgggcg gtattgtgct ggcgatgacg ctcaccgcga
   113041 cctatatcag tgccagttcg tttatcggcg ggccaggagc tgcttataaa tacgggctgg
   113101 gctgggtatt gctggcgatg attcagcttc ctgcagtctg gctttcactc ggtattctcg
   113161 gcaagaagtt tgcgattctt gcgcgccgct acaatgcagt gacgctgaac gatatgctgt
   113221 ttgcccgcta ccagagtcgt cttctggtgt ggctggcgag tttgagtttg ctggttgcgt
   113281 tcgttggtgc gatgaccgtg cagtttatcg gcggtgcgcg cctgctggaa accgcggcgg
   113341 gtattcctta tgaaaccggg ctgctgattt ttggtatcag cattgcgtta tataccgcct
   113401 ttggtggctt tcgcgccagc gtgctgaacg acaccatgca agggcttgtg atgctgattg
   113461 gcaccgttgt gctgcttatt ggcgtagtac atgccgctgg cggcttaagt aacgcagtac
   113521 agaccttgca aaccatcgat ccgcaactgg ttacgccaca aggcgctgac gatattctgt
   113581 cgcctgcctt tatgacgtcg ttctgggtac tggtgtgttt tggcgtgatt ggcctgccgc
   113641 atactgcggt gcgctgtatc tcttataaag acagcaaagc cgtacatcgg gggatcatca
   113701 tcggtacgat tgtggtcgca attctgatgt tcggtatgca cctggccgga gcgttaggtc
   113761 gggcggtgat ccccgatctc accgtaccgg acctggtgat cccaacgtta atggtaaaag
   113821 tgctgccacc gtttgctgcc gggatcttcc tggctgcacc gatggctgcg atcatgtcga
   113881 caattaacgc ccaactgctg caaagttccg ctacgatcat taaagatctc tatctgaata
   113941 tccgtccgga tcaaatgcaa aacgagacgc gtctgaagcg gatgtcggcg gtaattacgt
   114001 tagttctcgg cgcgttgctg ctgcttgccg cctggaagcc gccagaaatg atcatctggc
   114061 tgaatttgtt ggccttcggt gggctggaag ccgttttcct gtggccgctg gtgctgggtc
   114121 tttactggga acgcgccaac gccaaaggcg cgctaagtgc gatgatcgtt ggcggcgtgc
   114181 tgtatgccgt actcgcgacg ctgaatattc agtacctggg cttccaccct atcgtgccct
   114241 cgttactact aagtttgctg gctttcctgg tcggaaaccg tttcggtaca tccgtcccgc
   114301 aagctaccgt tttgactact gataaataaa gagttttgcc atgccttgga tccaactgaa
   114361 actgaacacc accggcgcga acgcggaaga tcttagcgat gcgctgatgg aagcgggtgc
   114421 cgtttctatc acttttcagg atacccacga tacgccagta tttgaaccgc tgccgggcga
   114481 aacgcgcctg tggggcgaca ccgatgtgat tggtctgttc gacgctgaaa ccgatatgaa
   114541 cgacgtggtg gcgattctgg aaaaccatcc gctgctcggc gcaggcttcg cgcataaaat
   114601 cgaacaacta gaagataaag actgggagcg cgaatggatg gataatttcc acccgatgcg
   114661 ctttggtgaa cgactgtgga tctgccctag ctggcgtgat gtgccggacg aaaacgccgt
   114721 caacgtgatg ttagatccag ggctggcgtt tggtacgggt acccatccaa ccacctctct
   114781 gtgcctgcaa tggctcgaca gcctcgattt aaccggtaaa acagtcatcg actttggctg
   114841 tggttccggc attctggcga tcgcggcgct gaaactgggt gcagcaaaag ccattggtat
   114901 tgatatcgat ccgcaggcga ttcaggccag ccgcgataac gccgaacgta atggcgtttc
   114961 tgaccgtctg gaactctact taccgaaaga tcagccagaa gaaatgaaag ccgacgtggt
   115021 ggtcgctaac atccttgcag gcccattacg tgaactggca ccgttaatca gcgtcctgcc
   115081 ggtttcaggc ggtttgctgg gcctttccgg tattctggca agccaggcag agagcgtttg
   115141 tgaagcttat gccgatagct tcgcactgga cccggtcgtg gaaaaagaag agtggtgccg
   115201 tattaccggt cgtaagaatt aaccttcgca tcgccgtagg gtgacgcggg gcgaagtgcg
   115261 agcaagctca caaaaggcac gtaaatttgc cgattattta cgcaaatttg cgtgccaaaa
   115321 ttttcattca taaagaaaaa ttgagaactt actcaaattt ctttgagtgt aaattttagt
   115381 cactattttc taatatgatg atttttatga gtaattatcg caccacgctc attttaaatg
   115441 caattctttg atccatctca gaggattggt caaagtttgg cctttcatct cgtgcaaaaa
   115501 atgcgtaata tacgccgcct tgcagtcaca gtatggtcat ttcttaactc atgcgcatcg
   115561 gacaatatca gctcagaaat cgcctgatcg cagcgcccat ggctggcatt acagacagac
   115621 cttttcggac gttgtgctac gagatgggag ccggattgac agtatccgag atgatgtctt
   115681 ctaacccaca ggtttgggaa agcgacaaat ctcgtttacg gatggtgcac attgatgaac
   115741 ccggtattcg caccgtgcaa attgctggta gcgatccgaa agaaatggca gatgcagcac
   115801 gtattaacgt ggaaagcggt gcccagatta ttgatatcaa tatgggttgc ccggctaaaa
   115861 aagtgaatcg caagctcgca ggttcagccc tcttgcagta cccggatgtc gttaaatcga
   115921 tccttaccga ggtcgtcaat gcagtggacg ttcctgttac cctgaagatt cgcaccggct
   115981 gggcaccgga acaccgtaac tgcgaagaga ttgcccaact ggctgaagac tgtggcattc
   116041 aggctctgac cattcatggc cgtacacgcg cctgtttgtt caatggagaa gctgagtacg
   116101 acagtattcg ggcagttaag cagaaagttt ccattccggt tatcgcgaat ggcgacatta
   116161 ctgacccgct taaagccaga gctgtgctcg actatacagg ggcggatgcc ctgatgatag
   116221 gccgcgcagc tcagggaaga ccctggatct ttcgggaaat ccagcattat ctggacactg
   116281 gggagttgct gcccccgctg cctttggcag aggttaagcg cttgctttgc gcgcacgttc
   116341 gggaactgca tgacttttat ggtccggcaa aagggtaccg aattgcacgt aaacacgttt
   116401 cctggtatct ccaggaacac gctccaaatg accagtttcg gcgcacattc aacgccattg
   116461 aggatgccag cgaacagctg gaggcgttgg aggcatactt cgaaaatttt gcgtaaacag
   116521 aaataaagag ctgacagaac tatgttcgaa caacgcgtaa attctgacgt actgaccgtt
   116581 tctaccgtta actctcagga tcaggtaacc caaaaacccc tgcgtgactc ggttaaacag
   116641 gcactgaaga actattttgc tcaactgaat ggtcaggatg tgaatgacct ctatgagctg
   116701 gtactggctg aagtagaaca gcccctgttg gacatggtga tgcaatacac ccgtggtaac
   116761 cagacccgtg ctgcgctgat gatgggcatc aaccgtggta cgctgcgtaa aaaattgaaa
   116821 aaatacggca tgaactaatt caggttagct aaatgcttga ttaaaaaggc gctactcggc
   116881 atggggaagc gcctttttta taggtgtcac aaagggagtg accatgagaa caggatgtga
   116941 accgacccgg tttggtaatg aagctaagac cattattcac ggtgatgcgc ttgccgaact
   117001 taaaaagatc cccgccgaaa gtgtcgatct gatctttgcc gacccaccat ataacatcgg
   117061 taaaaatttt gatggtctga tcgaagcctg gaaagaagat ctgtttatcg actggctgtt
   117121 tgaagtgatt gcagagtgcc accgcgttct gaaaaagcag ggcagcatgt acatcatgaa
   117181 cagcacggaa aacatgccct ttatcgatct ccagtgccgc aagcttttta ccatcaaaag
   117241 tcgcatcgtc tggtcatatg acagttctgg agtacaggcg aaaaaacact acggctccat
   117301 gtacgaaccc atcctgatga tggtgaaaga cgcaaagaac tacacattca acggtgatgc
   117361 tattctggta gaagccaaaa ccggatcgca gcgcgcgttg atcgattatc gcaaaaatcc
   117421 tccacagcca tacaatcatc aaaaagtacc gggtaacgtc tgggattttc cgcgcgtgcg
   117481 ttatttgatg gatgaatatg agaaccaccc gacgcaaaaa ccggaagcct tactgaaacg
   117541 cattattctc gcctcttcca acccaggcga tatcgttctc gacccgtttg ccggtagctt
   117601 tactaccggt gccgtagccg tctccagcgg gcgaaaattc attggtattg agatcaacag
   117661 cgagtacatc aaaatggggc ttcgacggct ggatgtcgcg tcgcattact ctgcggaaga
   117721 actggcgaaa gtgaaaaaaa gaaagaccgg caacctgtca aaacgaagcc ggttaagcga
   117781 agttgacccc gatctcattg caaagtaaag gaagtgtaag cctggttttc agattattca
   117841 tttcgtgtat atttcctgcc agacttggtt aaacatacac aggctcaggt aatgattcgc
   117901 aagtattggt ggctcgtcgt tttcgctgtc ttcgtttttc tgtttgatac tttactgatg
   117961 cagtggattg aactgctggc aacagaaaca gacaaatgcc gcaatatgaa ctcagttaat
   118021 ccactaaaac tggttaactg tgacgaactg aattttcagg acagaatgtg aatttacatg
   118081 acacttaatt cattcgtttg atgaattaat ttcgttatgt tttcatctgg catgaacatt
   118141 cttaatacgt tatcgaccag agcgggggct tgtttataaa gatcataacc cgccatattc
   118201 attaaccagt tttgaacaat tccgctgaag gcaccattaa taataatcat cacaacatct
   118261 aaatcgaggt tatttgctac acaaccttgt tgctgacacg cctgcaatac ttcgcggaga
   118321 gtctgcggat tgaagcccat cttttcgcgt atcactccct cggccagcat ctcatcatta
   118381 aattcacatt tgtgatataa gattttcagc aacgcctgct ggcggggaat tttggcaata
   118441 tattgcaagc cgacaatcaa tttttcacgc aattgttgaa acgggtcatg ctctaatcca
   118501 gccgtcaagt gttcctggat taactcccgc aatgaaggct gttgcaacca catctcatta
   118561 aacagttgag tcttgttttc gaagtgccag tagatagcgc cacgcgtaac gttagcagcg
   118621 tcggcaatgt cgttgagtgt cgtcttgctt acgccatgct gcgcaaactg ggcgatggca
   118681 gtttcaatca gttcttgccg ggtcttcaga gcttcggctt tggttctttt tgccatgatt
   118741 aattattcag gaaataaata tattcgacac agagtgagaa aatagcgaag gttaatct
//
LOCUS       DAPOAV010000003       116408 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.003, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000003 DAPOAV010000000
VERSION     DAPOAV010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 116408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 116408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..116408
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.003"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..117
                     /locus_tag="RN951_000241"
     CDS             <1..117
                     /locus_tag="RN951_000241"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417365.1"
                     /note="catalyzes the rearrangement of isopentenyl
                     diphosphate to dimethylallyl phosphate; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopentenyl-diphosphate delta-isomerase"
                     /protein_id="HDX2525307.1"
                     /translation="ADVLHGIDATPWAFSPWMVMQATNREARKRLSAFTQLK"
     gene            complement(161..1678)
                     /gene="lysS"
                     /locus_tag="RN951_000242"
     CDS             complement(161..1678)
                     /gene="lysS"
                     /locus_tag="RN951_000242"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDX2525308.1"
                     /translation="MSEQHAQGADAVVDLNNELKTRREKLANLREQGIAFPNDFRRDH
                     TSDQLHAEFDGKENEELEALNIEVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD
                     DLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGL
                     QDQEARYRQRYLDLISNDESRNTFKVRSQILSGIRQFMVNRGFMEVETPMMQVIPGGA
                     AARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFT
                     MMELYMAYADYKDLIELTESLFRTLAQDILGKTEVTYGDVTLDFGKPFEKLTMREAIK
                     KYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFEEVAEAHLIQPTFITE
                     YPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVAAKDAG
                     DDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMRPVK"
     gene            complement(1688..2786)
                     /gene="prfB"
                     /locus_tag="RN951_000243"
     CDS             complement(join(1688..2710,2712..2786))
                     /gene="prfB"
                     /locus_tag="RN951_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311790.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HDX2525309.1"
                     /translation="MFEINPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQP
                     DVWNEPERAQALGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAE
                     LDALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYLRWAESRG
                     FKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFS
                     SAFVYPEVDDDIDIEINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTGIVTQCQN
                     DRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDNKSDIGWGSQIRSYVLDDSRIK
                     DLRTGVETRNTQAVLDGSLDQFIEASLKAGL"
     gene            complement(2877..4610)
                     /gene="recJ"
                     /locus_tag="RN951_000244"
     CDS             complement(2877..4610)
                     /gene="recJ"
                     /locus_tag="RN951_000244"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HDX2525310.1"
                     /translation="MKQQIQLRRREVDETADLPAELPPLLRRLYASRGVRSAQELERS
                     VKGMLPWQQLSGVEKAVEILYNAFREGTRIIVVGDFDADGATSTALSVLAMRSLGCSN
                     IDYLVPNRFEDGYGLSPEVVDQAHARGAQLIVTVDNGISSHAGVVHARSLGIPVIVTD
                     HHLPGETLPAAEAIINPNLRDCNFPSKSLAGVGVAFYLMLALRTFLRDQGWFDERGIA
                     IPNLAELLDLVALGTVADVVPLDANNRILTWQGMSRIRAGKCRPGIKALLEVANRDAQ
                     KLAASDLGFALGPRLNAAGRLDDMSVGVALLLCDNIGEARVLANELDALNQTRKEIEQ
                     GMQVEALTLCEKLERSRDTLPGGLAMYHPEWHQGVVGILASRIKERFHRPVIAFAPAG
                     DGTLKGSGRSIQGLHMRDALERLDTLYPGMILKFGGHAMAAGLSLEEDKFELFQQRFG
                     ELVTEWLDPSLLQGEVVSDGPLSPAEMTMEVAQLLRDAGPWGQMFPEPLFDGHFRLLQ
                     QRLVGERHLKVMVEPVGGGPLLDGIAFNVDTALWPDNGVREVQLAYKLDINEFRGNRS
                     LQIIIDNIWPI"
     gene            complement(4616..5326)
                     /gene="dsbC"
                     /locus_tag="RN951_000245"
     CDS             complement(4616..5326)
                     /gene="dsbC"
                     /locus_tag="RN951_000245"
                     /EC_number="5.3.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional protein-disulfide
                     isomerase/oxidoreductase DsbC"
                     /protein_id="HDX2525311.1"
                     /translation="MKKGFMLFTLLAAFSGFAQADDAAIQQTLAKMGIKSSDIQPAPV
                     AGMKTVLTNSGVLYITDDGKHIIQGPMYDVSGTAPVNVTNKMLLKQLNALEKEMIVYK
                     APQEKHVITVFTDITCGYCHKLHEQMADYNALGITVRYLAFPRQGLDSDAEKEMKAIW
                     CAKDKNKAFDDVMAGKSVAPASCDVDIADHYALGVQLGVSGTPAVVLSNGTLVPGYQP
                     PKEMKEFLDEHQKMTSGK"
     gene            complement(5351..6247)
                     /gene="xerD"
                     /locus_tag="RN951_000246"
     CDS             complement(5351..6247)
                     /gene="xerD"
                     /locus_tag="RN951_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HDX2525312.1"
                     /translation="MKQDLARIEQFLDALWLEKNLAENTLNAYRRDLSMMVEWLHHRG
                     LTLATAQSDDLQALLAERLEGGYKATSSARLLSAVRRLFQYLYREKFREDDPSAHLAS
                     PKLPQRLPKDLSEAQVERLLQAPLIDQPLELRDKAMLEVLYATGLRVSELVGLTMSDI
                     SLRQGVVRVIGKGNKERLVPLGEEAVYWLETYLEHGRPWLLNGVSIDVLFPSQRAQQM
                     TRQTFWHRIKHYAVLAGIDSEKLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTT
                     QIYTHVATERLRQLHQQHHPRA"
     gene            6359..6880
                     /gene="fldB"
                     /locus_tag="RN951_000247"
     CDS             6359..6880
                     /gene="fldB"
                     /locus_tag="RN951_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldB"
                     /protein_id="HDX2525313.1"
                     /translation="MNMGLFYGSSTCYTEMAAEKIRDIIGPELVTLHNLKDDSPKLME
                     QYDVLILGIPTWDFGEIQEDWEAVWDQLDDLNLEGKIVALYGLGDQLGYGEWFLDALG
                     MLHDKLSTKGVKFVGYWPTEGYEFTSPKPVIADGQLFVGLALDETNQYDLSDERIQSW
                     CEQILNEMAEHYA"
     gene            complement(6920..7327)
                     /locus_tag="RN951_000248"
     CDS             complement(6920..7327)
                     /locus_tag="RN951_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YgfX"
                     /protein_id="HDX2525314.1"
                     /translation="MVLWQSDLRVSWRAQWLSLLIHGLVAAVILLMPWPLSYTPLWMV
                     LLSLVVFDCVRSQRRINARQGEIRLLMDGRLRWQGQEWCIVKAPWMIKSGMMLRLRSD
                     GGKRQHLWLAADSMDEAEWRDLRRILLQQETQR"
     gene            complement(7308..7574)
                     /gene="sdhE"
                     /locus_tag="RN951_000249"
     CDS             complement(7308..7574)
                     /gene="sdhE"
                     /locus_tag="RN951_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD assembly factor SdhE"
                     /protein_id="HDX2525315.1"
                     /translation="MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDEKRIFI
                     RLLECDDPDLFNWLMNHGKPADAELEMMVRLIQTRNRERGPVAI"
     gene            7817..8797
                     /gene="ygfZ"
                     /locus_tag="RN951_000250"
     CDS             7817..8797
                     /gene="ygfZ"
                     /locus_tag="RN951_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-modifying protein YgfZ"
                     /protein_id="HDX2525316.1"
                     /translation="MAFTPFPPRQPTASARLPLTLMTLDDWALATITGADSEKYMQGQ
                     VTADVSQMAEDQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVREPQLTELKKYA
                     VFSKVTIAPDDERVLLGVAGFQARAALANLFSELPSKEKQVVKEGATTLLWFEHPAER
                     FLIVTDEATANMLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQA
                     LGGISFKKGCYTGQEMVARAKFRGANKRALWLLAGSASRLPEAGEDLELKMGENWRRT
                     GTVLAAVKLEDGQVVVQVVMNNDMEPDSIFRVRDDANTLHIEPLPYSLEE"
     gene            complement(8874..9533)
                     /locus_tag="RN951_000251"
     CDS             complement(8874..9533)
                     /locus_tag="RN951_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HDX2525317.1"
                     /translation="MVQKPLIKQGYSLAEEIANSVSHGIGLVFGIVGLVLLLVQAVDL
                     NASATAITSYSLYGGSMILLFLASTLYHAIPHQRAKMWLKKFDHCAIYLLIAGTYTPF
                     LLVGLDSPLARGLMIVIWSLALLGILFKLTIAHRFKILSLVTYLAMGWLSLVVIYEMA
                     VKLAAGSVTLLAVGGVVYSLGVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYIGQ
                     A"
     gene            complement(9697..10008)
                     /locus_tag="RN951_000252"
     CDS             complement(9697..10008)
                     /locus_tag="RN951_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HDX2525318.1"
                     /translation="MQPNDITFFQRFQDDILAGRKTITIRDESESHFKTGDVLRVGRF
                     EDDGYFCTIEVTATSTVTLDTLTEKHAEQENMTLTELIKVIADIYPGQTQFYVIEFKC
                     L"
     gene            10053..11486
                     /gene="bglA"
                     /locus_tag="RN951_000253"
     CDS             10053..11486
                     /gene="bglA"
                     /locus_tag="RN951_000253"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708664.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase BglA"
                     /protein_id="HDX2525319.1"
                     /translation="MKKLTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLTGGAHG
                     VPREITKEVLPGKYYPNHEAVDFYGHYKEDIKLFAEMGFKCFRTSIAWTRIFPKGDEA
                     QPNEEGLKFYDDMFDELLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRFAE
                     VVFERYKHKVKYWMTFNEINNQRNWRAPLFGYCCSGVVYTEHENPEETMYQVLHHQFV
                     ASALAVKAARRINPEMKVGCMLAMVPLYPYCCNPDDVMFAQESMRERYVFTDVQLRGY
                     YPSYVLNEWERRGFNIKMEDGDLDVLREGTCDYLGFSYYMTNAVKAEGGTGDAISGFE
                     GSVPNPYVKASDWGWQIDPVGLRYALCELYERYQRPLFIVENGFGAYDKVEEDGSIND
                     DYRIDYLRAHIEEMKKAVTYDGVDLMGYTPWGCIDCVSFTTGQYSKRYGFIYVNKHDD
                     GAGDMSRSRKKSFNWYQEVIASNGEKL"
     gene            complement(11543..12286)
                     /locus_tag="RN951_000254"
     CDS             complement(11543..12286)
                     /locus_tag="RN951_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDX2525320.1"
                     /translation="MAIALVTGGSRGIGRATALLLAKEEYTLAVNYQQNLHAAQEVVN
                     LITQAGGKAFVLQADISDENQVIAMFTAIDQHDEPLAALVNNAGILFTQCTVENLTAE
                     RINRVLSTNVTGYFLCCREAVKRMALKNGGSGGAIVNVSSVASRLGSPGEYVDYAASK
                     GAIDTLTTGLSLEVAAQGIRVNCVRPGFIYTEMHASGGEPGRVDRVKSNIPMQRGGQA
                     EEVAQAIVWLLSDKASYVTGSFIDLAGGK"
     gene            complement(12552..15425)
                     /gene="gcvP"
                     /locus_tag="RN951_000255"
     CDS             complement(12552..15425)
                     /gene="gcvP"
                     /locus_tag="RN951_000255"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase"
                     /protein_id="HDX2525321.1"
                     /translation="MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQ
                     IVPKDIQLATPPQVGAPATEYAALAELKAIASRNKRFTSYIGMGYTAVQLPPVILRNM
                     LENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAM
                     AKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDVFGVLLQ
                     QVGTTGEIHDYTALISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVP
                     MGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNI
                     CTSQVLLANIASLYAVYHGPIGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLC
                     VEVADKAGVLTRAEAAEINLRSDILNAVGITLDETTTRENVMQLFNVLLGDNHGLDID
                     TLDKDVAHDSRSIQPAMLRDDEILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIP
                     LGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYQQMIAQLADWLVKLTGYDAVC
                     MQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVAC
                     DKNGNIDLTDLRAKAEQAGDNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDG
                     ANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVV
                     QIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQD
                     AFPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLM
                     VEPTESESKVELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQNELVAEWAHP
                     YSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISEYQ"
     gene            complement(15544..15933)
                     /gene="gcvH"
                     /locus_tag="RN951_000256"
     CDS             complement(15544..15933)
                     /gene="gcvH"
                     /locus_tag="RN951_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HDX2525322.1"
                     /translation="MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVD
                     LPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWI
                     FKIKASDESELESLLDATAYEALLEDE"
     gene            complement(15957..17051)
                     /gene="gcvT"
                     /locus_tag="RN951_000257"
     CDS             complement(15957..17051)
                     /gene="gcvT"
                     /locus_tag="RN951_000257"
                     /EC_number="2.1.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="HDX2525323.1"
                     /translation="MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHAVRTDA
                     GMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVY
                     YFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVRDDLSMIAVQGPNAQAKAATLF
                     NDAQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAGVKP
                     CGLGARDTLRLEAGMNLYGQEMDETISPLAANMGWTIAWEPADRDFIGREALEVQREH
                     GTEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVPEGI
                     GETAIVQIRNREMPVKVTKPVFVRNGKAVA"
     gene            17342..17425
                     /locus_tag="RN951_000258"
     CDS             17342..17425
                     /locus_tag="RN951_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2525324.1"
                     /translation="MSKNTKSKNNDIRKYNAKTEVKLVYFK"
     gene            complement(17499..18701)
                     /gene="ubiI"
                     /locus_tag="RN951_000259"
                     /gene_synonym="visC"
     CDS             complement(17499..18701)
                     /gene="ubiI"
                     /locus_tag="RN951_000259"
                     /gene_synonym="visC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent 2-octaprenylphenol hydroxylase"
                     /protein_id="HDX2525325.1"
                     /translation="MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADA
                     PPQLRVSAINAASEKLLTRLGVWQDILSRRASCYHGMEVWDKDSFGHISFDDQSMGYS
                     HLGHIVENSVIHYALWNKAQQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLV
                     IGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLS
                     DPHLCSIVWSLSPEEAQRMQQASEDEFNRALNIAFDNRLGLCKVESARQVFPLTGRYA
                     RQFAAHRLVLVGDAAHTIHPLAGQGVNLGFMDAAELIAELKRLHRQGKDIGQYIYLRR
                     YERSRKHSAALMLAGMQGFRDLFSGTNPAKKLLRDIGLKLADTLPGVKPQLIRQAMGL
                     NDLPEWLR"
     gene            complement(18724..19902)
                     /gene="ubiH"
                     /locus_tag="RN951_000260"
                     /gene_synonym="visB"
     CDS             complement(18724..19902)
                     /gene="ubiH"
                     /locus_tag="RN951_000260"
                     /gene_synonym="visB"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-6-methoxyphenyl hydroxylase"
                     /protein_id="HDX2525326.1"
                     /translation="MSVIIVGGGMAGATLALAISRLSHGALPVHLIEATAPESHAHPG
                     FDGRAIALAAGTCQQLARIGVWQSLADCATAITTVHVSDRGHAGFVTLAAEDYQLAAL
                     GQVVELHNVGQRLFALLRKAPGVMLHCPDRVANVARTQSHVEVTLESGEMLTGRVLIA
                     ADGTHSALATACGVDWQQEPYEQLAVIANVATSVAHEGRAFERFTQHGPLAMLPMSDG
                     RCSLVWCHPLERREEVLSWSDEKFCRELQSAFGWRLGKITHAGKRSAYPLALTRAARA
                     ITHRTVLVGNAAQTLHPIAGQGFNLGMRDVMSLAETLTQAHERGEDIGDYGILCRYQQ
                     RRQSDREATIGVTDSLVHLFANRWAPLVVGRNIGLMTMELFTPARDVLAQRTLGWVAR
                     "
     gene            complement(19899..21224)
                     /gene="pepP"
                     /locus_tag="RN951_000261"
     CDS             complement(19899..21224)
                     /gene="pepP"
                     /locus_tag="RN951_000261"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro aminopeptidase"
                     /protein_id="HDX2525327.1"
                     /translation="MSEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPY
                     RQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEK
                     LGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYTYADEIVNSALEKLRKGSRQNLTAP
                     ATMIDWRPIVHEMRLFKSPEEIAVLRRAGEITALAHTRAMEKCRPGMFEYHLEGEIHH
                     EFNRHGARYPSYNTIVGSGENGCILHYTENECELRDGDLVLIDAGCEYKGYAGDITRT
                     FPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSMQEVTGEVVRIMVSGLVKLGILKG
                     DVDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVEPGLYIAPD
                     AEVPEQYRGIGIRIEDDIVITETGNENLTASVVKKPEEIEALMAAARKQ"
     gene            complement(21250..21828)
                     /gene="ygfB"
                     /locus_tag="RN951_000262"
     CDS             complement(21250..21828)
                     /gene="ygfB"
                     /locus_tag="RN951_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708672.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0149 family protein YgfB"
                     /protein_id="HDX2525328.1"
                     /translation="MSIQNEMPGYNEMNQYLNQQGTGLTPAEMHGLISGMICGGNDDS
                     SWLPLLHDLTNEGMAFGHELAQALRKMHSATSDALQDDGFLFQLYLPDGDDVSVFDRA
                     DALAGWVNHFLLGLGVTQPKLDKVTGETGEAIDDLRNIAQLGYDEDEDQEELEMSLEE
                     IIEYVRVAALLCHDTFTHPQPTAPEVQKPTLH"
     gene            21996..22325
                     /gene="zapA"
                     /locus_tag="RN951_000263"
     CDS             21996..22325
                     /gene="zapA"
                     /locus_tag="RN951_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDX2525329.1"
                     /translation="MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKER
                     TRVTNTEQLVFIAALNISYELAQEKAKTRDYAASMEQRIRMLQQTIEQALLEQGRITE
                     KTNQNFE"
     gene            22367..22550
                     /gene="ssrS"
                     /locus_tag="RN951_000264"
     ncRNA           22367..22550
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="RN951_000264"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            22571..23173
                     /locus_tag="RN951_000265"
     CDS             22571..23173
                     /locus_tag="RN951_000265"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HDX2525330.1"
                     /translation="MTQLPELPLTLSRQEIRKMIRQRRRALTPEQQQEMGQQAATRMM
                     TYPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKRVYLPVLHPFSAGNLLFLNYHPQ
                     SELVMNRLKIHEPKLDVRDVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQ
                     HYKTQPVGYAHDCQLVEKLPVEEWDIPLPAVVTPSKVWEW"
     gene            complement(23274..23333)
                     /locus_tag="RN951_000266"
     CDS             complement(23274..23333)
                     /locus_tag="RN951_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HDX2525331.1"
                     /translation="MMRLAIILIVLLLISFPAY"
     gene            complement(23666..23725)
                     /gene="ibsC"
                     /locus_tag="RN951_000267"
     CDS             complement(23666..23725)
                     /gene="ibsC"
                     /locus_tag="RN951_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsC"
                     /protein_id="HDX2525332.1"
                     /translation="MMRLVIILIVLLLISFGAY"
     gene            complement(23954..25186)
                     /gene="serA"
                     /locus_tag="RN951_000268"
     CDS             complement(23954..25186)
                     /gene="serA"
                     /locus_tag="RN951_000268"
                     /EC_number="1.1.1.95"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDX2525333.1"
                     /translation="MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDD
                     EQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVF
                     NAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYG
                     HIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTK
                     NMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDP
                     FTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPL
                     HGGRRLMHIHENRPGVLTALNKIFAEQGVNIAAQYLQTSAQMGYVVIDIEADEDVAEK
                     ALQAMKAIPGTIRARLLY"
     gene            complement(25441..26100)
                     /gene="rpiA"
                     /locus_tag="RN951_000269"
     CDS             complement(25441..26100)
                     /gene="rpiA"
                     /locus_tag="RN951_000269"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HDX2525334.1"
                     /translation="MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKG
                     QIEGAVSSSDASTEKLKSLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTR
                     EKIIASVAEKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYRQGV
                     VTDNGNVILDVHGMEILDPIAMENAINAIPGVVTVGLFANRGADVALIGTPDGVKTIV
                     K"
     gene            complement(26156..26386)
                     /locus_tag="RN951_000270"
     CDS             complement(26156..26386)
                     /locus_tag="RN951_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001328908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2525335.1"
                     /translation="MHFAQRVRALVVLNGVALLLQFACKQGLATGELVRLFAPWSGIP
                     RLLHALFAGRKGMPAIARYFMDELTTRLANGV"
     gene            26528..27421
                     /gene="argP"
                     /locus_tag="RN951_000271"
     CDS             26528..27421
                     /gene="argP"
                     /locus_tag="RN951_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator ArgP"
                     /protein_id="HDX2525336.1"
                     /translation="MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLEN
                     MFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSL
                     ATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLG
                     ALDYLFVSSKPFAEKYFPNGVTRSALLKAPVVAFDHLDDMHQAFLQQNFDLPPGSVPC
                     HIVNSSEAFVQLARQGTTCCMIPHLQIEKELASGELIDLTPGLFQRRMLYWHRFAPES
                     RMMRKVTDALLDYGHKVLRQD"
     gene            27625..29769
                     /gene="scpA"
                     /locus_tag="RN951_000272"
     CDS             27625..29769
                     /gene="scpA"
                     /locus_tag="RN951_000272"
                     /EC_number="5.4.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA mutase"
                     /protein_id="HDX2525337.1"
                     /translation="MSNEQEWQQLANKELSRREKTVDSLVQQTAEGIAIKPLYTEADL
                     DNLEVTGTLPGLPPYVRGPRATMYTAQPWTIRQYAGFSTAKESNAFYRRNLAAGQKGL
                     SVAFDLATHRGYDSDNPRVAGDVGKAGVAIDTVEDMKVLFDQIPLDKMSVSMTMNGAV
                     LPVLAFYIVAAEEQGVTPDKLTGTIQNDILKEYLCRNTYIYPPKPSMRIIADIIAWCS
                     GNMPRFNTISISGYHMGEAGANCVQQVAFTLADGIEYIKAAISAGLKIDDFAPRLSFF
                     FGIGMDLFMNVAMLRAARYLWSEAVSGFGAQDPKSLALRTHCQTSGWSLTEQDPYNNV
                     IRTTIEALAATLGGTQSLHTNAFDEALGLPTDFSARIARNTQIIIQEESELCRTVDPL
                     AGSYYIESLTDQIVKQARAIIQQIDEAGGMAKAIEAGLPKRMIEEASAREQSLIDQGK
                     RVIVGVNKYKLDHEDETDVLEIDNVMVRNEQIASLERIRATRDDAAVTAALNALTHAA
                     QHNENLLAAAVNAARVRATLGEISDALEAAFDRYLVPSQCVTGVIAQSYHQSEKSASE
                     FDAIVAQTEQFLADNGRRPRILIAKMGQDGHDRGAKVIASAYSDLGFDVDLSPMFSTP
                     EEIARLAVENDVHVVGASSLAAGHKTLIPELVEALKKWGREDICVVAGGVIPPQDYAF
                     LQERGVAAIYGPGTPMLDSVRDVLNLISQHHD"
     gene            29762..30757
                     /gene="meaB"
                     /locus_tag="RN951_000273"
     CDS             29762..30757
                     /gene="meaB"
                     /locus_tag="RN951_000273"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl Co-A mutase-associated GTPase
                     MeaB"
                     /protein_id="HDX2525338.1"
                     /translation="MINEATLAESIRRLRQGERATLAQAMTLVESRHPRHQALSTQLL
                     DAIMPYCGNTLRLGVTGTPGAGKSTFLEAFGMLLIREGLKVAVIAVDPSSPVTGGSIL
                     GDKTRMNDLARAEAAFIRPVPSSGHLGGASQRARELMLLCEAAGYDVVIVETVGVGQS
                     ETEVARMVDCFISLQIAGGGDDLQGIKKGLMEVADLLVINKDDGDNHTNVAIARHMYE
                     SALHILRRKYDEWQPRVLTCSALEKRGIDEIWHAIIDFKTALTASGRLQQVRQQQSVE
                     WLRKQTEEEVLNHLFANEDFDRYYRQTLLAVKNNTLSPRTGLRQLSEFIQTQYFD"
     gene            30768..31553
                     /gene="scpB"
                     /locus_tag="RN951_000274"
     CDS             30768..31553
                     /gene="scpB"
                     /locus_tag="RN951_000274"
                     /EC_number="7.2.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311816.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA decarboxylase"
                     /protein_id="HDX2525339.1"
                     /translation="MSYQYVNVVTINKVAVIEFNYGRKLNALSKVFIDDLMQALSDLN
                     RPEIRCIILRAPSGSKVFSAGHDIHELPSGGRDPLSYDDPLRQITRMIQKFPKPIISM
                     VEGSVWGGAFEMIMSSDLIIAASTSTFSMTPVNLGVPYNLVGIHNLTRDAGFHIVKEL
                     IFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHHISEKAPLAIAVIKEELRVLGE
                     AHTMNSDEFERIQGMRRAVYDSEDYQEGMNAFLEKRKPNFVGH"
     gene            31577..33055
                     /gene="scpC"
                     /locus_tag="RN951_000275"
     CDS             31577..33055
                     /gene="scpC"
                     /locus_tag="RN951_000275"
                     /EC_number="2.8.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionyl-CoA:succinate CoA transferase"
                     /protein_id="HDX2525340.1"
                     /translation="METQWTRMTADEAAEIIQHNDMVAFSGFTPAGSPKALPTAIARR
                     ANEQHEAKKPYQIRLLTGASISAAADDVLSDADAVSWRAPYQTSSGLRKKINQGAVSF
                     VDLHLSEVAQMVNYGFFGDIDVAVIEASALAPDGRVWLTSGIGNAPTWLLRAKKVIIE
                     LNHYHDPRVAELADIVIPGAPPRRNSVSIFHAMDRVGTRYVQIDPKKIVAVVETNLPD
                     AGNMLDKQNPMCQQIADNVVTFLLQEMAHGRIPPEFLPLQSGVGNINNAVMARLGENP
                     EIPPFMMYSEVLQESVVHLLETGKISGASASSLTISADSLRKIYDNMDYFASRIVLRP
                     QEISNNPEIIRRLGVIALNVGLEFDIYGHANSTHVAGVDLMNGIGGSGDFERNAYLSI
                     FMAPSIAKEGKISTVVPMCSHVDHSEHSVKVIITEQGIADLRGLSPLQRARTIIDNCA
                     HPMYRDYLHRYLENAPGGHIHHDLSHVFDLHRNLIATGSMLG"
     gene            complement(33052..33948)
                     /locus_tag="RN951_000276"
     CDS             complement(33052..33948)
                     /locus_tag="RN951_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417396.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX2525341.1"
                     /translation="MDIFISKKMRNFILLAQTNNIARAAEKIHMTASPFGKSIAALEE
                     QIGYTLFTRKDNNISLNKAGQELYQKLFPVYQRLSAIDNEIHNSGRRSREIVIGIDNT
                     YPTIIFDQLISLGDKYEGVTAQPVEFSENGVIDNLFDRQLDFIISPQHVSARVQELEN
                     LTISELPPLRLGFLVSRRYEERQEQELLQELPWLQMRFQNRANFEAMIDANMRPCGIN
                     PTIIYRPYSFMAKISAVERGHFLTVIPHFAWRLVNPATLKYFDAPHRPMYMQEYLYSI
                     RNHRYTATMLQHIAEDRDGTSH"
     gene            complement(34115..34855)
                     /locus_tag="RN951_000277"
     CDS             complement(34115..34855)
                     /locus_tag="RN951_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative stress defense protein"
                     /protein_id="HDX2525342.1"
                     /translation="MKFKVIALAALMGISGMAAQANELPDGPHIVTSGTASVDAVPDI
                     ATLAIEVNVAAKDAATAKKQADERVAQYISFLELNQIAKKDISSANLRTQPDYDYQDG
                     KSILKGYRAVRTVEVTLRQLDKLNSLLDGALKAGLNEIRSVSLGVAQPDAYKDKARKA
                     AIDNAIHQAQELANGFHRKLGPVYSVRYHVSNYQPSPMVRMMKADAAPVSAQETYEQA
                     AIQFDDQVDVVFQLEPVDQQPAKTPAAQ"
     gene            complement(34948..35583)
                     /gene="argO"
                     /locus_tag="RN951_000278"
     CDS             complement(34948..35583)
                     /gene="argO"
                     /locus_tag="RN951_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine exporter ArgO"
                     /protein_id="HDX2525343.1"
                     /translation="MFSYYFQGLALGAAMILPLGPQNAFVMNQGIRRQYHIMIALLCA
                     ISDLVLICAGIFGGSALLMQSPWLLALVTWGGVAFLLWYGFGAFKTAMSSNIELASAE
                     VLKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWF
                     FGLAILAAWLAPRLRTAKSQRIINLVVGCVMWFIALQLARDGIAHAQALFS"
     gene            complement(35722..36582)
                     /gene="mscS"
                     /locus_tag="RN951_000279"
     CDS             complement(35722..36582)
                     /gene="mscS"
                     /locus_tag="RN951_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small-conductance mechanosensitive channel MscS"
                     /protein_id="HDX2525344.1"
                     /translation="MEDLNVVDSINGAGSWLVANQALLLSYAVNIVAALAIIIVGLII
                     ARMISNAVNRLMISRKIDATVADFLSALVRYGIIAFTLIAALGRVGVQTASVIAVLGA
                     AGLAVGLALQGSLSNLAAGVLLVMFRPFRAGEYVDLGGVAGTVLSVQIFSTTMRTADG
                     KIIVIPNGKIIAGNIINFSREPVRRNEFIIGVAYDSDIDQVKQILTNIIQSEDRILKD
                     REMTVRLNELGASSINFVVRVWSNSGDLQNVYWDVLERIKREFDAAGISFPYPQMDVN
                     FKRVKEDKAA"
     gene            complement(36940..38019)
                     /gene="fbaA"
                     /locus_tag="RN951_000280"
     CDS             complement(36940..38019)
                     /gene="fbaA"
                     /locus_tag="RN951_000280"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HDX2525345.1"
                     /translation="MSKIFDFVKPGVITGDDVQKVFQVAKENNFALPAVNCVGTDSIN
                     AVLETAAKVKAPVIVQFSNGGASFIAGKGVKSDVPQGAAILGAISGAHHVHQMAEHYG
                     VPVILHTDHCAKKLLPWIDGLLDAGEKHFAATGKPLFSSHMIDLSEESLQENIEICSK
                     YLERMSKIGMTLEIELGCTGGEEDGVDNSHMDASALYTQPEDVDYAYTELSKISPRFT
                     IAASFGNVHGVYKPGNVVLTPTILRDSQEYVSKKHNLPHNSLNFVFHGGSGSTAQEIK
                     DSVSYGVVKMNIDTDTQWATWEGVLNYYKANEAYLQGQLGNPKGEDQPNKKYYDPRVW
                     LRAGQTSMIARLEKAFQELNAIDVL"
     gene            complement(38234..39397)
                     /gene="pgk"
                     /locus_tag="RN951_000281"
     CDS             complement(38234..39397)
                     /gene="pgk"
                     /locus_tag="RN951_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HDX2525346.1"
                     /translation="MSVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTI
                     ELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVA
                     EGELVVLENVRFNKGEKKDDETLSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADV
                     ACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIA
                     NTFIAAQGHDVGKSLYEADLVDEAKRLLTTCNIPVPSDVRVATEFSETAPATLKSVND
                     VKADEQILDIGDASAQELAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEA
                     FSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK"
     gene            complement(39447..40466)
                     /gene="epd"
                     /locus_tag="RN951_000282"
     CDS             complement(39447..40466)
                     /gene="epd"
                     /locus_tag="RN951_000282"
                     /EC_number="1.2.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="erythrose-4-phosphate dehydrogenase"
                     /protein_id="HDX2525347.1"
                     /translation="MTVRVAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGM
                     AHLLKYDTSHGRFAWEVRQERDQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGV
                     YGSREHGEAHIAAGAKKVLFSHPGSNDLDATVVYGVNQDQLRAEHRIVSNASCTTNCI
                     IPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAG
                     ITRFFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIV
                     DYTELPLVSVDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMA
                     TVAFR"
     gene            40838..41269
                     /locus_tag="RN951_000283"
     CDS             40838..41269
                     /locus_tag="RN951_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDX2525348.1"
                     /translation="MMTLPYPYSSSARFYALRLLPGQEVFSQLHAFAQQHQLHAAWIA
                     GCTGSLTDVALRYAGQEGTTLLNGTFEVISLNGTLEQSGEHLHLCVSDPHGTMLGGHM
                     MPGCTVRTTLELVIGSLEELAFSRQPCALSGYDELHISPVK"
     gene            41292..41870
                     /locus_tag="RN951_000284"
     CDS             41292..41870
                     /locus_tag="RN951_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDX2525349.1"
                     /translation="MARSHFSSQALVLIVISIAINMIGGQLASMVKLPIFLDSIGTLI
                     SAVLLGPVIGMLTGLLTNLLWGLLTNPIAAAFAPVAMVIGLVAGCLARAGWFRTLPKV
                     VVSGVIITLAVTVVAVPLRTALFGGVTGSGADLFVAWMHSMGQNLVESVAITVIGANL
                     VDKILTAVIVWLLLRQLPIRTTRHFPAMAAVR"
     gene            41871..42578
                     /locus_tag="RN951_000285"
     CDS             41871..42578
                     /locus_tag="RN951_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDX2525350.1"
                     /translation="MHPFTSLTLWALAACTTLILPAQTILPIYSAATFFCLIALKATR
                     RRAKYVVWLMFSLGAGLWLVHGGWLPEWLSGTPRSPERWSHAITLWLRILAIVSTSQL
                     WMQYVPVQCFIRALFASRLPPGVAYLFAGPLLVVEQLKRQLAIIHEAQRARGVPLDEG
                     WYQRLRAMPALIIPLTHNALNDLAVRGAALDMRAFRIHNRRTTLWAPADSTLQRVARY
                     TMILLMLTEFGAWIWLR"
     gene            42566..43243
                     /locus_tag="RN951_000286"
     CDS             42566..43243
                     /locus_tag="RN951_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDX2525351.1"
                     /translation="MVTLEQFRYCPTHSTHPPFCYDFHYVKPGMVAIFGDNGSGKSTL
                     AQLMAGWYPDFLPGEITGTGTLLGTPIGHLPLNEQSATIQLVQQSPYLQLSGCTFSVE
                     EEVAFGPENLCLAEAEIMARIDAALTLTECQPLRHRHPATLSGGETQRVVIACAIAMQ
                     PKLLILDEAFSRLTPQASEMLLQRLQHWAFERGSLIILFERHRTPFLNYCQQAWQLQN
                     GALQPLC"
     gene            43237..43914
                     /locus_tag="RN951_000287"
     CDS             43237..43914
                     /locus_tag="RN951_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HDX2525352.1"
                     /translation="MLTLNKISYRWPGAATDCLCDISLQLKQGEWLALTGDNGAGKST
                     LLRVMAGLLTPTAGTVMLQQQAMKNLKNRQRAAKIGVLFQEAENQLFHSTVADEIAFG
                     LKLQKCPADEITQRTHAALQCCQLADTANAHPLDLHSAQRRMVAVACLEALSPPLLLL
                     DEPSRDFDENWLSVFESWLEKCRQRGTSVVAISHDAAFTRRHFSRVVRLEDGLIRNVN
                     PPDDIHP"
     gene            complement(43886..44599)
                     /locus_tag="RN951_000288"
     CDS             complement(43886..44599)
                     /locus_tag="RN951_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside/nucleotide kinase family protein"
                     /protein_id="HDX2525353.1"
                     /translation="MNIELTVNGLKVQAQYSDDEIENVHKPLLRMLAALQAVSSQRRT
                     VVFLCAPPGTGKSTLTTFWEYLAQQDPELPAIQTLPMDGFHHYNSWLDAHQLRPFKGA
                     PETFDVVKLAENLRQVVEGDCTWPQYDRQKHDPVEDALHVTAPLVIVEGNWLLLDDEK
                     WCQLAQFCDFSIFINAPATALRERLVGRKLAGGVSLADAEAFYDRTDGPNVRRVLEES
                     LPANLTLMMTATGEYRLVD"
     gene            complement(44596..45105)
                     /gene="fumE"
                     /locus_tag="RN951_000289"
     CDS             complement(44596..45105)
                     /gene="fumE"
                     /locus_tag="RN951_000289"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarase E"
                     /protein_id="HDX2525354.1"
                     /translation="MATLTEDDVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVD
                     NDEEIVEYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQD
                     ETPGFADDMTWDFISNVNSITCNATLYDALKAMKFADFAVWSEARFSGMVKTALTLAV
                     TTTLKELTP"
     gene            complement(45127..46092)
                     /gene="yggF"
                     /locus_tag="RN951_000290"
     CDS             complement(45127..46092)
                     /gene="yggF"
                     /locus_tag="RN951_000290"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphatase"
                     /protein_id="HDX2525355.1"
                     /translation="MMSLAWPLFRVTEQAALAAWPQTGCGDKNKIDGLAVTAMRQALN
                     DVAFRGRVVIGEGEIDHAPMLWIGEEVGKGDGPEVDIAVDPIEGTRMVAMGQSNVLAV
                     MAFAPRDSLLHAPDMYMKKLVVNRLAAGAIDLSLPLADNLRNVARALGKPLDKLRMVT
                     LDKPRLSAAIEEATQLGVKVFALPDGDVAASVLTCWQDNPYDVMYTIGGAPEGVISAC
                     AVKALGGDMQAELIDFCQAKGDYTENRQIAEQERKRCKAMGVDVNRVYSLDELVRGND
                     ILFSATGVTGGELVNGIQQTANGVRTQTLLIGGADQTCNIIDSLH"
     gene            complement(46089..47366)
                     /locus_tag="RN951_000291"
     CDS             complement(46089..47366)
                     /locus_tag="RN951_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HDX2525356.1"
                     /translation="MKTKVAAIYGKRDVRLREFELPEITDNELLESVISDSVCLSTWK
                     AALLGSEHKRVPDDLENHPVITGHECAGVIVEVGKNLTGKYKKGQRFVLQPAMGLPSG
                     YSAGYSYEYFGGNATYMIIPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYH
                     TTQYVYEHRMGVKPGGNIALLACAGPMGIGAIDYAINGGIQPSRVVVVDIDDKRLAQV
                     QKLLPVDLAASKGIELVYVNTKGMSDPVQTLRALTGDVGFDDIFVYAAVPAVVEMADE
                     LLAEDGCLNFFAGPTDKNFKVPFNFYNVHYNSTHVVGTSGGSTDDMKEAIALSATGQL
                     QPSFMVTHIGGLDAVPDTVLNLPDIPGGKKLIYNGVTMPLTAIADFAEKGKTDPLFKE
                     LARLVEETHGIWNEQAEKYLLAQFGVDIGEAAQ"
     gene            complement(47381..48769)
                     /gene="cmtA"
                     /locus_tag="RN951_000292"
     CDS             complement(47381..48769)
                     /gene="cmtA"
                     /locus_tag="RN951_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HDX2525357.1"
                     /translation="MENKSARAKVQAFGGFLTAMVIPNIGAFIAWGFITALFIPTGWL
                     PNEHFAKIVGPMITYLLPVMIGSTGGHLVGGKRGAVMGGIGTIGVIVGAEIPMFLGSM
                     IMGPLGGLVIKYVDKALEKRIPAGFEMVINNFSLGIAGMLLCLLGFEVIGPAVLIANT
                     FVKECIEALVHAGYLPLLSVINEPAKVLFLNNAIDQGVYYPLGMQQASVNGKSIFFMV
                     ASNPGPGLGLLLAFTLFGKGMSKRSAPGAMIIHFLGGIHELYFPYVLMKPLTIIAMIA
                     GGMSGTWMFNLLDGGLVAGPSPGSIFAYLALTPKGSFLATIAGVTVGTLVSFAITSLI
                     LKMEKTVETESEDEFAQSANAVKAMKQEGAFSLSRVKRIAFVCDAGMGSSAMGATTFR
                     KRLEKAGLAIEVKHYAIENVPADADIVVTHASLEGRVKRVTDKPLILINNYIGDPKLD
                     TLFNQLTAEHKH"
     gene            complement(48797..49231)
                     /gene="cmtB"
                     /locus_tag="RN951_000293"
     CDS             complement(48797..49231)
                     /gene="cmtB"
                     /locus_tag="RN951_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001555649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IIA"
                     /protein_id="HDX2525358.1"
                     /translation="MIIFPESSISVIHSAKDWQEAIDFSMVSLLDKNYISENYIQAIK
                     DSTINNGPYYILAPGVAMPHARPECGALKTGMSLTLLEQGVYFPGNDEPIKLLIGLSA
                     ADADSHIGAIQALSELLCEEEILEQLLTASSEKQLADIISRG"
     gene            complement(49555..51546)
                     /gene="tkt"
                     /locus_tag="RN951_000294"
     CDS             complement(49555..51546)
                     /gene="tkt"
                     /locus_tag="RN951_000294"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDX2525359.1"
                     /translation="MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDF
                     LKHNPQNPSWADRDRFVLSNGHGSMLIYSLLHLTGYDLPMEELKNFRQLHSKTPGHPE
                     VGYTAGVETTTGPLGQGIANAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDGCMME
                     GISHEVCSLAGTLKLGKLIAFYDDNGISIDGHVEGWFTDDTAMRFEAYGWHVIRDIDG
                     HDAASIKRAVEEARAVTDKPSLLMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREQ
                     LGWKYAPFEIPSEIYAQWDAKEAGQAKESAWNEKFAAYAKAYPQEAAEFTRRMKGEMP
                     SDFDAKAKEFIAKLQANPAKIASRKASQNAIEAFGPLLPEFLGGSADLAPSNLTLWSG
                     SKAINEDAAGNYIHYGVREFGMTAIANGISLHGGFLPYTSTFLMFVEYARNAVRMAAL
                     MKQRQVMVYTHDSIGLGEDGPTHQPVEQVASLRVTPNMSTWRPCDQVESAVAWKYGVE
                     RQDGPTALILSRQNLAQQERTEEQLANIARGGYVLKDCAGQPELIFIATGSEVELAVA
                     AYEKLTAEGVKARVVSMPSTDAFDKQDAAYRESVLPKAVTARVAVEAGIADYWYKYVG
                     LNGAIVGMTTFGESAPAELLFEEFGFTVDNVVAKAKELL"
     gene            51824..52582
                     /gene="loiP"
                     /locus_tag="RN951_000295"
                     /gene_synonym="yggG"
     CDS             51824..52582
                     /gene="loiP"
                     /locus_tag="RN951_000295"
                     /gene_synonym="yggG"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311838.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease LoiP"
                     /protein_id="HDX2525360.1"
                     /translation="MKIRALLVAMSVATVLTGCQNMDSNGLLSSGAEAFQAYSLSDAQ
                     VKTLSDQACQEMDSKATIAPANSEYAKRLTTIANALGNNINGQPVNYKVYMAKDVNAF
                     AMANGCIRVYSGLMDMMTDNEVEAVIGHEMGHVALGHVKKGMQVALGTNAVRVAAASA
                     GGIVGSLSQSQLGDLGEKLVNSQFSQRQEAEADDYSYDLLRQRGISPAGLATSFEKLA
                     KLEEGRQSSMFDDHPASAERAQHIRDRMSADGVK"
     gene            complement(52638..53381)
                     /locus_tag="RN951_000296"
     CDS             complement(52638..53381)
                     /locus_tag="RN951_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HDX2525361.1"
                     /translation="MQKINFYRNRVAINVLAKDIANAREIFDAAEGHAVIGVLSAQFS
                     SVDEGIQEVKRWMAEIPSISVGLGAGDPAQYYKAAMIAAQIHPAHVNQTFTGCGFAAG
                     ALAATGGEQTHVNALVSPTGTPGEVLISTGVSSSQGTPARVSCDTAVRMMLDMGAHAA
                     KFFPMGGERSLPELYALATTAARNGMTLIEPTGGIDLDNFSVILKTCLEAGVPRIMPH
                     VYSSIIDPDTGYTRPDDVAVLLNKVKSLL"
     gene            complement(53368..54477)
                     /gene="dgaE"
                     /locus_tag="RN951_000297"
     CDS             complement(53368..54477)
                     /gene="dgaE"
                     /locus_tag="RN951_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-glucosaminate-6-phosphate ammonia lyase"
                     /protein_id="HDX2525362.1"
                     /translation="MTQNIYQQLGLKQVINACGKMTILGVSSVAPEVMQATARAASSF
                     VEIDQLVDKTGELVSRFTGAEDSYVTSCASAGIAIAVAAAITRGDKARVALMPDSSGM
                     ANEVVMLRGHNVDYGASILSAIRLGGGRVVEVGSSNLAALWQLESAITDATVALLYVK
                     SHHCVQKGMLNIEDFAHVAQMYNLPLIVDAAAEEDLRAWVVSGADMVVYSGAKAFNAP
                     TSGFITGKKIWIAACKAQHHGIARAMKIGKENMVGLVYALENYHQGQAVITAEQLQPV
                     VEAISAIHGLTADIEQDEAGRAIWRIRIRVNAQELGVDARVVEAQLRGGDIAIYARRY
                     NLHQGVFSLDPRTVAEGEMALIVARLKEIADHAKD"
     gene            complement(54481..55341)
                     /locus_tag="RN951_000298"
     CDS             complement(54481..55341)
                     /locus_tag="RN951_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462668.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDX2525363.1"
                     /translation="MMSDDVMQHELVERARESGTLTKADITKAWFIYWLGAEVSSSYE
                     RLQSLIFCASMTPIIKKLYPQKEEQVEALKRHLNFFNSEQTFGAVIQGISIAMEEQKT
                     RGEAINDASITGIKTGLMGPLAGMGDSIIWAAVMPLLIAIFIPFAANGSAMGGILPLI
                     LYPAITLAISYGMVHKGYTLGRDSIISLLQGGRIKELIYGANVLGLIMMGALSASFVK
                     ITSPLKISALKGSEVVVQQILDSIAPGLLPLAAVFAIYFYLVKKGPRYTTILLSIVAL
                     SVVCSLLGVL"
     gene            complement(55338..56087)
                     /locus_tag="RN951_000299"
     CDS             complement(55338..56087)
                     /locus_tag="RN951_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDX2525364.1"
                     /translation="MDTLLFASLMGLYYWFARLRLGYTFSAMLLQPVVVAVFVGLLLG
                     NMPAAMIIGAGMQLVYLGVTSTPGGNVPSDPALAACIAIPIAVKANMDPNLAIALAIP
                     FGVIGVFLDQLRRTLNAAWVHMADKHAETANMSAIMRCAFLYPALLGLVLRFPVVFAA
                     NYFGQNVVESFLKLMPHWLTHSFEIMGGILPALGFAITIMVIGKKSLLPWFIGGFFAV
                     LYLKVDIMAMAIFGTCVAFLIKGLAKNEGAA"
     gene            complement(56113..56598)
                     /locus_tag="RN951_000300"
     CDS             complement(56113..56598)
                     /locus_tag="RN951_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HDX2525365.1"
                     /translation="MANIVLCRIDSRLIHGQVVTKWVGQSQANRIAVVSDELDADPFM
                     KNIYLMAAPPNIKVDCFSNQSFAAAWKENQLGDGNVLVLFPSLAAIQEAVQQGFDVAD
                     IQVGGLGGGPNRKAVFQNITLDEKDVGILNDLKSRGIKAVFQTIPEDKPQSLDDILKK
                     F"
     gene            complement(56609..57037)
                     /locus_tag="RN951_000301"
     CDS             complement(56609..57037)
                     /locus_tag="RN951_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDX2525366.1"
                     /translation="MTTTVPIHPLPEILLLTHGGWGLQLCNSLRMVMGEIEGVTEIAL
                     MPVDTLGEFYQRVEAVVKTMPEGSLIVTDFIGGTTSNVAARLSADYPVAVISGLNASL
                     LLEALDKREHGPLTACVADLVEAGRNSCLDVVSHIRQLQQ"
     gene            complement(57156..59954)
                     /gene="dagR"
                     /locus_tag="RN951_000302"
     CDS             complement(57156..59954)
                     /gene="dagR"
                     /locus_tag="RN951_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DagR"
                     /protein_id="HDX2525367.1"
                     /translation="MRRIDVIHKELERLTYGLELSDLAKEKAFTAEAIGFNLGLARNS
                     VSKDLNQLWNEGLVVKSQGRPVFFLHRHALELLINRKLDDCECIVHSVASLLPKKEKY
                     TDDDPFSGLIGYDRSLRDAVEKGRAAVLYPHGLHVLLTGASGVGKTFFAELMHCFACK
                     HTIGSPPPLVYFNCAEYAHNPELLSSHLFGHHKGAFTGASENKTGLVEQADGGYLLLD
                     EVHRLPYEGQEKLFSILDKGEYRPLGSSGPTYSISVRLICATTESVNSALLRTFQRRI
                     QVCIDLPGIRQRSVEEQLELIVSFFQRESRKIERTISLDKTLLHWLLSNPLEGNIGQL
                     KSDIQFLCAQAWASGMTERNDTLELDKRLAEMSFNTTPEQRLLVDALFGGKDRLNVDA
                     RTLPALKNSLATSAEIEESDLFYSFLTREYVNLRNSNVPPAETLAILKNKLSSIFEYG
                     LYSRHSAAHPPRYGDQIEERVTLLIGYVEQVLGFTLPENLANPLRKHFLALIGYVRRG
                     LIPQLYSSSLILDRCKDEYDNATLLCRKINELLHIQCPATEVVWLCLFLKECRHYRQR
                     IDTSPDCGVILIAHGATTATSQAQYVNRVLERDLFYAIDMPFEQSVHDTLETLTRMIQ
                     DRCWQRLILMVDIGSLVHFGSTISKLFQIDVLLLPNITLTSLLEVGLDLSYETGDLSQ
                     LAVLMQSKNIPCRLCTPQQESGGKVLVISCITGMGTAEKIKKVLEESFGELMSQDTRM
                     VILDYNEVRSLERIQQALNASERLAGIVGTFQPGLPDIPFISLEELFSEQGPELVLSL
                     LTPDLSSSERRLEMERSAMRFISALTMESIINHISVLNPQRILKEIEDVLNYLTNTLS
                     LKPSRQVTLRFLIHCCCMVERIVINRKPLQMALENRLDLDARAFSVIKSSFLPIEEAY
                     AIRLSDAEYFYIYELLYS"
     gene            complement(60213..61133)
                     /gene="speB"
                     /locus_tag="RN951_000303"
     CDS             complement(60213..61133)
                     /gene="speB"
                     /locus_tag="RN951_000303"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HDX2525368.1"
                     /translation="MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDM
                     ATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMRERLNVVDCGDLVYAFGDAREMS
                     EKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCE
                     FDHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDVIAQVKQ
                     IVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVA
                     PAYDQSEITALAAATLALEMLYIQAAKKGE"
     gene            complement(61269..62000)
                     /locus_tag="RN951_000304"
     CDS             complement(61269..62000)
                     /locus_tag="RN951_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2525369.1"
                     /translation="MKKWKVRSALVALIVLLAGCSSNAQYNSSASGNVGTAWGGDVHS
                     SVQGVSAERAWRDPAEMIVISYSTNVPSGYDRVYSIRINELEYAIRDGNFNSLPITRV
                     YDSSNNEPRYIVHARVGMNYQLYVRNYSRNTNYEIVATVDGMDVLNGKQGSLNNNGYI
                     VNAGDSLAIKGFRKDKHTEAAFQFANVADSYAANSAQGDVRNTGVIGFAAFELQGPAQ
                     NALPPCSGQAFPADNNGYAPPPCRK"
     gene            complement(62146..64122)
                     /gene="speA"
                     /locus_tag="RN951_000305"
     CDS             complement(62146..64122)
                     /gene="speA"
                     /locus_tag="RN951_000305"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic arginine decarboxylase"
                     /protein_id="HDX2525370.1"
                     /translation="MSDDMSMGLPSSAGEHGVLRSMQEVAMSSQEASKMLRTYNIAWW
                     GNNYYDVNELGHISVCPDPDVPEARVDLAQLVKTREAQGQRLPALFCFPQILQHRLRS
                     INAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLA
                     HAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLDEAERLNVVPR
                     LGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLREAGRLDSLQLLHFHLGSQ
                     MANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNE
                     YANNIIWAIGDACEENGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTVPTAPAE
                     DAPRALQSMWETWQEMHEPGTRRSLREWLHDSQMDLHDIHIGYSSGTFSLQERAWAEQ
                     LYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFPVL
                     PLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVG
                     AYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTQF
                     RDQVKKTDLDAELQQQFLEEFEAGLYGYTYLEDE"
     gene            complement(64131..64262)
                     /gene="yqgB"
                     /locus_tag="RN951_000306"
     CDS             complement(64131..64262)
                     /gene="yqgB"
                     /locus_tag="RN951_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417414.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid stress response protein YqgB"
                     /protein_id="HDX2525371.1"
                     /translation="MKKKPVAQLERQHSLLENPCAYGLLSQFQAAIVVNCFTLNKII"
     gene            64398..64613
                     /locus_tag="RN951_000307"
     CDS             64398..64613
                     /locus_tag="RN951_000307"
                     /inference="COORDINATES: protein motif:HMM:NF037550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2525372.1"
                     /translation="MGITSAGMQSRDAECGERIFTRTVRQVKQQTTVHYFVSPPRPPV
                     KTNPQAKTLISTRLEVATRKKRRVLFI"
     gene            64917..66071
                     /gene="metK"
                     /locus_tag="RN951_000308"
     CDS             64917..66071
                     /gene="metK"
                     /locus_tag="RN951_000308"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HDX2525373.1"
                     /translation="MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACET
                     YVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPD
                     INQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPW
                     LRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLT
                     SATKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAA
                     YAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPSEQLTLLVREFF
                     DLRPYGLIQMLDLLHPIYKETAAYGHFGREHFPWEKTDKAQLLRDAAGLK"
     gene            66507..67901
                     /gene="galP"
                     /locus_tag="RN951_000309"
     CDS             66507..67901
                     /gene="galP"
                     /locus_tag="RN951_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/proton symporter"
                     /protein_id="HDX2525374.1"
                     /translation="MPDAKKQERSNKAMTFFVCFLAALAGLLFGLDIGVIAGALPFIA
                     DEFQITSHTQEWVVSSMMFGAAVGAVGSGWLSFKLGRKKSLMIGAILFVAGSLFSAAA
                     PNVEVLILSRVLLGLAVGVASYTAPLYLSEIAPEKIRGSMISMYQLMITIGILGAYLS
                     DTAFSYTGAWRWMLGVIIIPAILLLIGVFFLPDSPRWFAAKRRFVDAERVLLRLRDTS
                     AEAKRELDEIRESLQVKQSGWALFKENSNFRRAVFLGVLLQVMQQFTGMNVIMYYAPK
                     IFELAGYTNTTEQMWGTVIVGLTNVLATFIAIGLVDRWGRKPTLTLGFLVMAAGMGVL
                     GTMMHIGIHSPSAQYFAIAMLLMFIVGFAMSAGPLIWVLCSEIQPLKGRDFGITCSTA
                     TNWIANMIVGATFLTMLNTLGNANTFWVYAALNVLFILLTLWLVPETKHVSLEHIERN
                     LMKGRKLREIGAHD"
     gene            67978..68475
                     /locus_tag="RN951_000310"
     CDS             67978..68475
                     /locus_tag="RN951_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family zinc-dependent metalloprotease"
                     /protein_id="HDX2525375.1"
                     /translation="MKTSRLPIAIQQAVMRRLREKLAQANLKLGRNYPEPKLSYTQRG
                     TSAGTAWLESYEIRLNPVLLLENSEAFIEEVVPHELAHLLVWKHFGRVAPHGKEWKWM
                     MESVLGVPARRTHQFELQSVRRNTFPYRCKCQEHQLTVRRHNRVVRGEAVYRCVHCGE
                     QLVAK"
     gene            68570..69277
                     /gene="endA"
                     /locus_tag="RN951_000311"
     CDS             68570..69277
                     /gene="endA"
                     /locus_tag="RN951_000311"
                     /EC_number="3.1.21.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease I"
                     /protein_id="HDX2525376.1"
                     /translation="MYRYLSIAAVVLSAAFSGPALAEGINSFSQAKAAAVKVHADAPG
                     TFYCGCKINWQGKKGVVDLQSCGYQVRKNENRASRVEWEHVVPAWQFGHQRQCWQDGG
                     RKNCAKDPVYRKMESDMHNLQPSVGEVNGDRGNFMYSQWNGGEGQYGQCAMKVDFKEK
                     AAEPPARARGAIARTYFYMRDQYNLTLSRQQTQLFNAWNKMYPVTDWECERDERIAKV
                     QGNHNPYVQRACQARKS"
     gene            69357..70088
                     /gene="rsmE"
                     /locus_tag="RN951_000312"
     CDS             69357..70088
                     /gene="rsmE"
                     /locus_tag="RN951_000312"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014226833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HDX2525377.1"
                     /translation="MRIPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFD
                     GSNQVFDAEITSASKKSVEVKVLEGKIDDRESPLHIHLGQVMSRGEKMEFTIQKSIEL
                     GVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWC
                     AEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLG
                     PRVLRTETTALTAITALQVRFGDLG"
     gene            70101..71051
                     /gene="gshB"
                     /locus_tag="RN951_000313"
     CDS             70101..71051
                     /gene="gshB"
                     /locus_tag="RN951_000313"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione synthase"
                     /protein_id="HDX2525378.1"
                     /translation="MIKLGIVMDPIANINIKKDSSFAMLLEAQRRGYELHYMEMGDLY
                     LINGEARAHTRTLNVKQNYEEWFSFVGEQDLPLVDLDVILMRKDPPFDTEFIYATYIL
                     ERAEEKGTLIVNKPQSLRDCNEKLFTAWFSDLTPETLVTRNKAQLKAFWEKHSDIILK
                     PLDGMGGASIFRVKEGDPNLGVIAETLTEHGTRYCMAQNYLPAIKDGDKRVLVVDGEP
                     VPYCLARIPQGGETRGNLAAGGRGEPRPLTESDWKIARQIGPTLKEKGLIFVGLDIIG
                     DRLTEINVTSPTCIREIEAEFPVSITGMLMDAIEARLQQQ"
     gene            71160..71723
                     /locus_tag="RN951_000314"
     CDS             71160..71723
                     /locus_tag="RN951_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgE/AlgH family protein"
                     /protein_id="HDX2525379.1"
                     /translation="MNLQHHFLIAMPALQDPIFRRSVVYICEHNTNGAMGIIVNKPLE
                     NLKIEGILEKLKITPEPRDESIRLDKPVMLGGPLAEDRGFILHTPPSNFASSIRISDN
                     TVMTTSRDVLETLGTDKQPSDVLVALGYASWEKGQLEQEILDNAWLTAPADLNILFKT
                     PIADRWREAAKLIGVDILTMPGVAGHA"
     gene            71723..72139
                     /gene="ruvX"
                     /locus_tag="RN951_000315"
     CDS             71723..72139
                     /gene="ruvX"
                     /locus_tag="RN951_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HDX2525380.1"
                     /translation="MSGTLLAFDFGTKSIGVAVGQRITGTARPLPAIKAQDGTPDWNL
                     IERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVEVKLHDERLSTVE
                     ARSGLFEQGGYRALNKGKVDSASAVIILESYFEQGY"
     gene            complement(72315..73295)
                     /locus_tag="RN951_000316"
     CDS             complement(72315..73295)
                     /locus_tag="RN951_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HDX2525381.1"
                     /translation="MNMEEIVALSVKHNVSDLHLCSAWPARWRIRGLMEAAPFDAPDV
                     EELLREWLDDDQRAILLENGQLDFAVSLAENQRLRGSAFAQRQGISLALRLLPSHCPQ
                     LEQLGAPTVLPELLKSENGLILVTGATGSGKSTTLAAMVGYLNQHADAHILTLEDPVE
                     YIYASQRCLIQQREIGLHCMTFASGLRAALREDPDVILLGELRDSETIRLALTAAETG
                     HLVLATLHTRGAAQAVERLVDSFPAQEKDPVRNQLAGSLRAVLSQKLEVDKQEGRVAL
                     FELLINTPAVGNLIREGKTHQLPHVIQTGQQVGMLTFQQSYQQRVGEGRL"
     gene            73313..74017
                     /gene="yggS"
                     /locus_tag="RN951_000317"
     CDS             73313..74017
                     /gene="yggS"
                     /locus_tag="RN951_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate homeostasis protein"
                     /protein_id="HDX2525382.1"
                     /translation="MNDIAHNLAQVRDKISAAATRCGRSPEEITLLAVSKTKPASAIA
                     EAIDAGQRQFGENYVQEGVDKIRHFQELGVTGLEWHFIGPLQSNKSRLVAEHFDWCHT
                     IDRLRIATRLNDQRPAELPPLNVLIQINISDENSKSGIQLAELDELAAAVAELPRLRL
                     RGLMAIPAPESEYVRQFEVARQMAVAFAGLKTRYPHIDTLSLGMSDDMEAAIAAGSTM
                     VRIGTAIFGARDYSKK"
     gene            74035..74601
                     /gene="yggT"
                     /locus_tag="RN951_000318"
     CDS             74035..74601
                     /gene="yggT"
                     /locus_tag="RN951_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotic shock tolerance protein YggT"
                     /protein_id="HDX2525383.1"
                     /translation="MNTLTFLLSTVIELYTMVLLLRIWMQWAHCDFYNPFSQFVVKVT
                     QPIIGPLRRVIPAMGPIDSASLLVAYILSFIKAIVLFKVVTFLPIIWIAGLLILLKTI
                     GLLIFWVLLVMAIMSWVSQGRSPIEYVLIQLADPLLRPIRRLLPAMGGIDFSPMILVL
                     LLYVINMGVAEVLQATGNMLLPGLWMAL"
     gene            74598..74888
                     /locus_tag="RN951_000319"
     CDS             74598..74888
                     /locus_tag="RN951_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417428.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggU family protein"
                     /protein_id="HDX2525384.1"
                     /translation="MSAVTVNDDGLVLRLYIQPKASRDSIVGLHGDEVKVAITAPPVD
                     GQANSHLVKFLGKQFRVAKSQVVIEKGELGRHKQIKIINPQQIPPEIAALIN"
     gene            74896..75489
                     /locus_tag="RN951_000320"
     CDS             74896..75489
                     /locus_tag="RN951_000320"
                     /EC_number="3.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XTP/dITP diphosphatase"
                     /protein_id="HDX2525385.1"
                     /translation="MQKVVLATGNAGKVRELASLLSDFGLDIVAQTDLGVDSAEETGL
                     TFIENAILKARHAAKVTGLPAIADDSGLAVDVLGGAPGIYSARYSGEDATDLKNLQKL
                     LETLKDVPDDQRQARFHCVLVYLRHAEDPTPLVCHGSWPGVITREPAGTGGFGYDPIF
                     FVPSEGKTAAELTREEKSAISHRGQALKLLLDALRNG"
     gene            75482..76618
                     /gene="hemW"
                     /locus_tag="RN951_000321"
     CDS             75482..76618
                     /gene="hemW"
                     /locus_tag="RN951_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HDX2525386.1"
                     /translation="MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLL
                     CDLDNDVAYAQGREVKTIFIGGGTPSLLSGPAMQTLLDGVRARLPLAADAEITMEANP
                     GTVEADRFVDYQRAGVNRISIGVQSFSEEKLKRLGRIHGPQEAKRAAKLASGLGLRSF
                     NLDLMHGLPDQSLEEALGDLRQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALW
                     DIFEQGHQLLTAAGYQQYETSAYAKPGYQCQHNLNYWRFGDYIGIGCGAHGKVTFPDG
                     RILRTTKTRHPRGFMQGRYLESQRDVEAADKPFEFFMNRFRLLEAAPRAEFIAYTGLC
                     EDVIRPQLDEAIAQGYLTECADYWQITEHGKLFLNSLLELFLAE"
     gene            complement(76773..77780)
                     /locus_tag="RN951_000322"
     CDS             complement(76773..77780)
                     /locus_tag="RN951_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1202 family protein"
                     /protein_id="HDX2525387.1"
                     /translation="MKKQWIVGTALLMLMTGNAWADGEPPTENILKDQFKKQYHGILK
                     LDAITLKNLDAKGNQATWSAEGDVSSSDDLYTWVGQLADYELLEQTWTKDKPVKFSAM
                     LTSKGTPASGWSVNFYSFQAAASDRGRVVDDIKTNNKYLIVNSEDFNYRFSQLESALN
                     TQKNSIPALEKEVKALDKQMVAAQKAADAYWGKDANGKQMTREDAFKKIHQQRDEFNK
                     QNDSEAFAVKYDKEVYQPAIAACHKQSEECYEVPIQQKRDFDINEQRRQTFLQSQKLS
                     RKLQDDWVTLEKGQYPLTMKVSEINSKKVAILMKIDDINQANERWKKDTEQLRRNGVI
                     K"
     gene            complement(77897..78943)
                     /gene="ansB"
                     /locus_tag="RN951_000323"
     CDS             complement(77897..78943)
                     /gene="ansB"
                     /locus_tag="RN951_000323"
                     /EC_number="3.5.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparaginase 2"
                     /protein_id="HDX2525388.1"
                     /translation="MEFFKKTALAALVMGFSGAALALPNITILATGGTIAGGGDSATK
                     SNYTAGKVGVENLVNAVPQLKDIANVKGEQVVNIGSQDMNDNVWLTLAKKINTDCDKT
                     DGFVITHGTDTMEETAYFLDLTVKCDKPVVMVGAMRPSTSMSADGPFNLYNAVVTAAD
                     KASANRGVLVVMNDTVLDGRDVTKTNTTDVATFKSVNYGPLGYIHNGKIDYQRTPARK
                     HTSDTPFDVSKLNELPKVGIVYNYANASDLPAKALVDAGYDGIVSAGVGNGNLYKSVF
                     DTLATAAKNGTAVVRSSRVPTGATTQDAEVDDAKYGFVASGTLNPQKARVLLQLALTQ
                     TKDPQQIQQIFNQY"
     gene            complement(79119..79838)
                     /locus_tag="RN951_000324"
     CDS             complement(79119..79838)
                     /locus_tag="RN951_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2884 domain-containing protein"
                     /protein_id="HDX2525389.1"
                     /translation="MMRKMLLAAALSVTAMTAHADYQCSVTPRDDVIVSPQTVQVKGE
                     NGNLVITPDGNVMYNGKQYSLNAAQREQAKDYQAELRSTLPWIDEGAKSRVEKARIAL
                     DKIIVQEMGESSKMRSRLTKLDAQLKEQMNRIIETRSDGLTFHYKAIDQVRAEGQQLV
                     NQAMGGILQDSINEMGAKAVLKSGGNPLQNVLGSLGGLQSSIQTEWKKQEKDFQQFGK
                     DVCSRVVTLEDSRKALVGNLK"
     gene            complement(80022..80348)
                     /locus_tag="RN951_000325"
     CDS             complement(80022..80348)
                     /locus_tag="RN951_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417434.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggL family protein"
                     /protein_id="HDX2525390.1"
                     /translation="MAKNRSRRLRKKMHIDEFQELGFSVAWRFPEGTSEEQIDKTVDD
                     FINEVIEPNKLAFDGSGYLAWEGLICMQEIGKCTEEHQAIVRKWLEERKLDEVRTSEL
                     FDVWWD"
     gene            complement(80348..81067)
                     /gene="trmB"
                     /locus_tag="RN951_000326"
     CDS             complement(80348..81067)
                     /gene="trmB"
                     /locus_tag="RN951_000326"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HDX2525391.1"
                     /translation="MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPV
                     MGVEFSEDMLDFPALFGREAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGA
                     CLASAHEEGLSNLRVMCHDAVEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVP
                     FAELVKSKLQLGGVFHMATDWEPYAEHMLEVMSSIDGYKNLSESNDYVPRPASRPVTK
                     FEQRGHRLGHGVWDLMFERVK"
     gene            81228..82280
                     /gene="mutY"
                     /locus_tag="RN951_000327"
     CDS             81228..82280
                     /gene="mutY"
                     /locus_tag="RN951_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HDX2525392.1"
                     /translation="MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQ
                     VATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGG
                     KFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEV
                     ENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWSL
                     YPGKKPKQTLPERTGYFLLLQHEDEVLLAQRPPSGLWGGLYCFPQFADEESLRHWLAQ
                     RQIAADNLTQLTAFRHTFSHFHLDIVPMWLPVSSFTGCMDEGNALWYNLAQPPSVGLA
                     APVERLLQQLRTGAPV"
     gene            82308..82583
                     /locus_tag="RN951_000328"
     CDS             82308..82583
                     /locus_tag="RN951_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative damage protection protein"
                     /protein_id="HDX2525393.1"
                     /translation="MSRTIFCTFLQREAEGQDFQLYPGELGKRIYNEISKEAWAQWQH
                     KQTMLINEKKLNMMNAEHRKLLEQEMVNFLFEGKEVHIEGYTPEDKK"
     gene            82648..83727
                     /gene="mltC"
                     /locus_tag="RN951_000329"
     CDS             82648..83727
                     /gene="mltC"
                     /locus_tag="RN951_000329"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417438.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltC"
                     /protein_id="HDX2525394.1"
                     /translation="MKKYLALALIAPLLISCSTTKKGDTYNEAWVKDTNGFDILMGQF
                     AHNIENIWGFKEVVIAGPKDYVKYTDQYQTRSHINFDDGTITIETIAGTEPAAHLRRA
                     IIKTLLMGDDPSSVDLYSDVDDITISKEPFLYGQVVDNTGQPIRWEGRASNFADYLLK
                     NRLKSRSNGLRIIYSVTINMVPNHLDKRAHKYLGMVRQASRKYGVDESLILAIMQTES
                     SFNPYAVSRSDALGLMQVVQHTAGKDVFRSQGKSGTPSRSFLFDPASNIDTGTAYLAM
                     LNNVYLGGIDNPTSRRYAVITAYNGGAGSVLRVFSNDKIQAANIINTMTPGDVYQTLT
                     TRHPSAESRRYLYKVNTAQKSYRRR"
     gene            83929..85185
                     /gene="nupG"
                     /locus_tag="RN951_000330"
     CDS             83929..85185
                     /gene="nupG"
                     /locus_tag="RN951_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease NupG"
                     /protein_id="HDX2525395.1"
                     /translation="MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVY
                     SSLGIAAVFMPALLGIVADKWLSAKWVYAICHTIGAITLFMAAQVTTPEAMFLVILIN
                     SFAYMPTLGLINTISYYRLQNAGMDIVTDFPPIRIWGTIGFIMAMWVVSLSGFELSHM
                     QLYIGAALSAILVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSM
                     LLGAELQITNMFGNTFLHSFDKDPMFASSFIVQHASIIMSISQISETLFILTIPFFLS
                     RYGIKNVMMISIVAWILRFALFAYGDPTPFGTVLLVLSMIVYGCAFDFFNISGSVFVE
                     KEVSPAIRASAQGMFLMMTNGFGCILGGIVSGKVVEMYTQNGITDWQTVWLIFAGYSV
                     VLAFAFMAMFKYKHVRVPTGTQTVSH"
     gene            complement(85235..87370)
                     /gene="speC"
                     /locus_tag="RN951_000331"
     CDS             complement(85235..87370)
                     /gene="speC"
                     /locus_tag="RN951_000331"
                     /EC_number="4.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417440.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase"
                     /protein_id="HDX2525396.1"
                     /translation="MKSMNIAASSELVSRLSSHRRVVALGDTDFTDVAAVVITAADSR
                     SGILALLKRTGFHLPVFLYSEHAVELPAGVTAVINGNEQQWLELESAACQYEENLLPP
                     FYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMCNADVKLGD
                     LLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKS
                     NHHGALIQAGATPVYLEASRNPFGFIGGIDAHCFNEEYLRQQIRDVAPEKAELPRPFR
                     LAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAWVGYEQFIPMMADSSPLLLELNE
                     NDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYP
                     LFAALDVNAKIHEGESGRRLWAECVEIGIEARKAILARCKLFRPFIPPVVDGKLWQDY
                     PTSVLASDRRFFSFEPGAKWHGFEGYAADQYFVDPCKLLLTTPGINAETGEYSDFGVP
                     ATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLAQFEQHIEDDSPLAE
                     VLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQQSFPSVVMNPQDAH
                     SAYIRGEVELVRIRDAEGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGVNL
                     LPGFSPELQGVYSETDADGMKRLYGYVLK"
     gene            87768..88475
                     /locus_tag="RN951_000332"
     CDS             87768..88475
                     /locus_tag="RN951_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HDX2525397.1"
                     /translation="MVIGPFINASAVLLGGVLGALLSQRLPERIRVSMTSIFGLASLG
                     IGILLVVKCANLPAMVLATLLGALIGEICLLEKGVNTAVAKAQNLFRHSRKKPAHESF
                     IQNYVAIIVLFCASGTGIFGAMNEGMTGDPSILIAKSFLDFFTAMIFACSLGIAVSVI
                     SIPLLIIQLTLAWAAALILPLTTPSMMADFSAVGGLLLLATGLRICGIKMFPVVNMLP
                     ALLLAMPLSAAWTAWFA"
     gene            88581..88656
                     /locus_tag="RN951_000333"
     tRNA            88581..88656
                     /locus_tag="RN951_000333"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:88614..88616,aa:Phe,seq:gaa)
     gene            complement(88805..89341)
                     /gene="yghD"
                     /locus_tag="RN951_000334"
     CDS             complement(88805..89341)
                     /gene="yghD"
                     /locus_tag="RN951_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GspM family type II secretion system protein
                     YghD"
                     /protein_id="HDX2525398.1"
                     /translation="MLRDKFIHYFQQWRERQLSRGEHWLAQHLAGRSPREKGMLLAAV
                     VFLFSVGYYVLIWQPLSERIEQQETMLQQLVAMNTRLRSAAPDIMAARKSATTTPAQV
                     SRVISDSASAHSVVIKRIAERGENIQVWIDPVVFNDLLNWLNALDEKYALRVTQIDAS
                     AAEKTGMVNVQRLEFGRG"
     gene            complement(89343..90521)
                     /gene="gspL"
                     /locus_tag="RN951_000335"
     CDS             complement(89343..90521)
                     /gene="gspL"
                     /locus_tag="RN951_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000097227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspL"
                     /protein_id="HDX2525399.1"
                     /translation="MSSILEIFFPLCAADPIHWQRRTPDVEHGIWSDVANEQLQQWLQ
                     TDAIRLYIPGEWISVWQVELPDVARKQIPTILPALLEEELNQDIDELHFAPLNIDQQL
                     ATVAVIHQQHMRNIAQWLQENGITRATVAPDWMSIPCGFMACDAQRVICRIDECRGWS
                     AGLALAPVMFRAQLNEQDLPLSLTVVGIAPEKLSAWAGADAERLTVTALPAITTYGEP
                     EGNLLTGPWQPRVSYRKQWARWRVMILPILLILVALAVERGVTLWSVSEQVAQSRTQA
                     EEQFLTLFPEQKRIVNLRSQVTMALKKYRPQADDTRLLAELSAIASTLKSASLSDIEM
                     RGFTFDQKRQILHLQLRAANFASFDKLRSALATDYVVQQDALQKEGDAVSGGVTLRRK
                     "
     gene            complement(90518..91495)
                     /gene="gspK"
                     /locus_tag="RN951_000336"
     CDS             complement(90518..91495)
                     /gene="gspK"
                     /locus_tag="RN951_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001554494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspK"
                     /protein_id="HDX2525400.1"
                     /translation="MITSPPKRGMALVVVLVLLAVMMLVTITLSGRMQQQLGRTRSQQ
                     EYQQALWYSASAESLALSALSLSLKNEKRVHLEQPWASGPRFFPLPQGQIAVTLRDAQ
                     ACFNLNALAQPTTASRPLAVQQLIALITRLDVPAYRAELIAESLWEFIDEDRSVQTRL
                     GREDSEYLARSVPFYAANQPLADISEMRVVQGMDAGLYQKLKPLVCALPMTRQQININ
                     TLDVTQSVILEALFDPWLSPVQARALLQQRPAKGWEDVDQFLAQPLLADVDERTKKQL
                     KTVLSVDSNYFWLRSDITVNEIELTMNSLIVRMGPQHFSVLWHQTGESE"
     gene            complement(91498..92097)
                     /gene="gspJ"
                     /locus_tag="RN951_000337"
     CDS             complement(91498..92097)
                     /gene="gspJ"
                     /locus_tag="RN951_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspJ"
                     /protein_id="HDX2525401.1"
                     /translation="MRRTRAGFTLLEMLVAIAIFASLALMAQQVTNGVTRVNSAVAGH
                     DQKLNLMQQTMSFLTHDLTQMMPRPVRGDQGQREPALLAGAGVLASESEGMRFVRGGV
                     VNPLMRLPRSNLLTVGYRIHDGYLERLAWPLTDAAGSVKPTMQKLIPADSLRLQFYDG
                     TRWQESWSSVQAIPVAVRMTLHSPQWGEIERIWLLRGPQ"
     gene            complement(92094..92465)
                     /gene="gspI"
                     /locus_tag="RN951_000338"
     CDS             complement(92094..92465)
                     /gene="gspI"
                     /locus_tag="RN951_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001709020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspI"
                     /protein_id="HDX2525402.1"
                     /translation="MKRGFTLLEVMLALAIFALAATAVLQIASGALSNQQILEEKTVA
                     GWVAENQTALLYLMTREQRAVRQQGESDMAGSRWYWRTTPLSTGNALLQAVDIEVSLH
                     EDFSSVIQSRRAWFSAVGGQQ"
     gene            complement(92462..93025)
                     /gene="gspH"
                     /locus_tag="RN951_000339"
     CDS             complement(92462..93025)
                     /gene="gspH"
                     /locus_tag="RN951_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001394829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspH"
                     /protein_id="HDX2525403.1"
                     /translation="MPERGFTLLEIMLVIFLIGLASAGVVQTFATDSESPAKKAAQDF
                     LTRFAQFKDRAVIEGKTLGVLIDPPGYQFMQRRQGQWSPVSSTRLSAQVTVPKQVQML
                     LQPGSDIWQKEYALELQRRRLTLHDIELELQKEAKKKTPQIRFSPFEPATPFTLRFYS
                     AAQNACWAVKLAHDGALSLNQCDERMP"
     gene            complement(93029..93484)
                     /gene="gspG"
                     /locus_tag="RN951_000340"
     CDS             complement(93029..93484)
                     /gene="gspG"
                     /locus_tag="RN951_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003912123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system major pseudopilin GspG"
                     /protein_id="HDX2525404.1"
                     /translation="MNSLSRTQKPRAGFTLLEVMVVIVILGVLASLVVPNLLGNKEKA
                     DRQKAISDIVALENALDMYRLDNGRYPTTEQGLEALIQQPANMADSRNYRTGGYIKRL
                     PKDPWGNDYQYLSPGEKGLFDVYTLGADGQENGEGAGADIGNWNLQEFQ"
     gene            complement(93501..94724)
                     /gene="gspF"
                     /locus_tag="RN951_000341"
     CDS             complement(93501..94724)
                     /gene="gspF"
                     /locus_tag="RN951_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system inner membrane protein
                     GspF"
                     /protein_id="HDX2525405.1"
                     /translation="MALFYYQALERNGRKTKGMIEADSARHARQLLRGKELIPVHIEA
                     RMNTSSGGMLQRRRHAHRRVAAADLALFTRQLATLVQAAMPLETCLQAVSEQSEKLHV
                     KSLGMALRSRIQEGYTLSDSLREHPRVFDSLFCSMVAAGEKSGHLDVVLNRLADYTEQ
                     RQRLKSRLLQAMLYPLVLLVVATGVVTILLTAVVPKIIEQFDHLGHALPASTRTLIAM
                     SDALQASGVYWLAGLLGLLVLGQRLLKNPAMRLRWDQTVLRLPVTGRVARGLNTARFS
                     RTLSILTASSVPLLEGIQTAAAVSANRYVEQQLLLAADRVREGSSLRAALAELRLFPP
                     MMLYMIASGEQSGELETMLEQAAVNQEREFDTQVGLALGLFEPALVVMMAGVVLFIVI
                     AILEPMLQLNNMVGM"
     gene            complement(94724..96217)
                     /gene="gspE"
                     /locus_tag="RN951_000342"
     CDS             complement(94724..96217)
                     /gene="gspE"
                     /locus_tag="RN951_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system ATPase GspE"
                     /protein_id="HDX2525406.1"
                     /translation="MVPVAQETTANTVRLPYSFSRRFSLVAWCEASLEILHVHPLSLS
                     VLQELQRGLNAPFTLRQIDEAEFEQRLNAVWQRDSSEARQLMEDLGSAEDFFTLAEEL
                     PETEDLLESDDDAPIIKLINAMLAEAIKEGASDIHIETFEKSLVIRFRVDGTLHEMLR
                     PGRKLASLLVSRIKVMARLDIAEKRVPQDGRIALLLGGRAIDVRVSTMPSAWGERVVL
                     RLLDKNQARLTLERLGLSQQLTAQLRQLLHKPHGIFLVTGPTGSGKSTTLYAGLQELN
                     NHSRNILTVEDPIEYMIEGIGQTQVNTRVGMTFARGLRAILRQDPDVVMVGEIRDTET
                     AEIAVQASLTGHLVLSTLHTNTAVGAITRLQDMGVEPFLLSSSLTGVMAQRLVRTLCP
                     DCRQPAPATDEEKRLLGITDARTVTLYHPQGCPACNHKGFRGRTAIHELIVVDATLRD
                     LIHRQAGELELERYVRQHSAGIRSNGIEKVLAGETSLDEVLRVTMEA"
     gene            complement(96217..98277)
                     /gene="gspD"
                     /locus_tag="RN951_000343"
     CDS             complement(96217..98277)
                     /gene="gspD"
                     /locus_tag="RN951_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020234996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system secretin GspD"
                     /protein_id="HDX2525407.1"
                     /translation="MFWRDITLSVWRKKTTGLKTKKRLLPLVLAAALCSSPVWAEEAT
                     FTANFKDTDLKSFIETVGANLNKTIIMGPGVQGKVSIRTMTPLNERQYYQLFLNLLEA
                     QGYAVVPMENDVLKVVKSSAAKVEPLPLVGEGSDNYAGDEMVTKVVPVRNVSVRELAP
                     ILRQMIDSAGSGNVVNYDPSNVIMLTGRASVVERLTEVIQRVDHAGNRTEEVIPLDNA
                     SASEIARVLESLTKNSGENQPATLKSQIVADERTNSVIVSGDPATRDKMRRLIRRLDS
                     EMERSGNSQVFYLKYSKAEDLVDVLKQVSGTLTAAKEEAEGTVGSGREIVSIAASKHS
                     NALIVTAPQDIMQSLQSVIEQLDIRRAQVHVEALIVEVAEGSNINFGVQWASKDAGLM
                     QFANGTQIPIGTLGAAISQAKPQKGSTVISENGATTINPDTNGDLSTLAQLLSGFSGT
                     AVGVVKGDWMALVQAVKNDSSSNVLSTPSITTLDNQEAFFMVGQDVPVLTGSTVGSNN
                     SNPFNTVERKKVGIMLKVTPQINEGNAVQMVIEQEVSKVEGQTSLDVVFGERKLKTTV
                     LANDGELIVLGGLMDDQAGESVAKVPLLGDIPLIGNLFKSTADKKEKRNLMVFIRPTI
                     LRDGMAADGVSQRKYNYMRAEQIYRDEQGLSLMPHTAQPVLPAQNQALPPEVRAFLNA
                     GRTR"
     gene            complement(98307..99266)
                     /gene="gspC"
                     /locus_tag="RN951_000344"
     CDS             complement(98307..99266)
                     /gene="gspC"
                     /locus_tag="RN951_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspC"
                     /protein_id="HDX2525408.1"
                     /translation="MARVVFRDARIYLIQWLTKIRHTLNQRQSFNTDKEHLRKIVRGM
                     FWLMLLIISAKVAHSLWRYFSFSAEYTDVSPSANKPPRADAKTFDKNDVQLISQQNWF
                     GKYQPVATPVKQPEPVPVAETRLNVVLRGIAFGARPGAVIEEGGKQQVYLQGETLGSH
                     NAVIEEINRDHVMLRYQGKIERLSLAEEERSTVAATNKKAVSDEAKQAVAEPAVSAPV
                     EIPTAVRQALAKDPQKIFNYIQLTPVRKEGIVGYAVKPGADRSLFDASGFKEGDIAIA
                     LNQQDFTDPRAMIALMRQLPSMDSIQLTVLRKGARHDISIALR"
     gene            complement(99284..99694)
                     /gene="gspS2"
                     /locus_tag="RN951_000345"
     CDS             complement(99284..99694)
                     /gene="gspS2"
                     /locus_tag="RN951_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system pilot lipoprotein
                     GspS-beta"
                     /protein_id="HDX2525409.1"
                     /translation="MSIKQMPGRVLISLLLSVTGLLSGCASHNENASLLAKKQAQNIS
                     QNLPIKSAGYTLVLAQSSGTTVKMTIISEAGTQTTQTPDAFLTSYQRQMCADPTVKLM
                     ITEGINYSITINDTRTGNQYQRKLDRTTCGIVKA"
     gene            complement(99760..100569)
                     /gene="pppA"
                     /locus_tag="RN951_000346"
     CDS             complement(99760..100569)
                     /gene="pppA"
                     /locus_tag="RN951_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417446.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase PppA"
                     /protein_id="HDX2525410.1"
                     /translation="MLFDVFQQYPAAMPILATVGGLIIGSFLNVVIWRYPIMLRQQMA
                     EFHGEMPSAQSKISLALPRSHCPHCQQTIRIRDNIPLLSWLMLKGRCRDCQAKISKRY
                     PLVELLTALAFLLASLVWPESGWALAVMILSAWLIAASVIDLDHQWLPDVFTQGVLWT
                     GLIAAWAQQSPLTLQDAVTGVLVGFIAFYSLRWIAGVVLRKEALGMGDVLLFAALGSW
                     VGPLSLPNVALIASCCGLIYAVITKRGSTTLPFGPCLSLGGIATIYLQALF"
     gene            complement(100717..105285)
                     /gene="sslE"
                     /locus_tag="RN951_000347"
     CDS             complement(100717..105285)
                     /gene="sslE"
                     /locus_tag="RN951_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein metalloprotease SslE"
                     /protein_id="HDX2525411.1"
                     /translation="MNKKFKYKKSLLAAILSATLLAGCDGGGSGSSSDTPPVDSGTGS
                     LPEVKPDPTPNPEPTPEPTPDPEPTPEPTPDPEPTPEPEPEPVPTKTGYLTLGGSLRV
                     TGDITCNDESSDGFTFTPGDKVTCVAGNNTTIATFDTQSEAARSLRAVEKVSFSLEDA
                     QELAGSDNKKSNALSLVTSMNSCPANTEQVCLEFSSVIESKRFDSLYKQIDLAPEEFK
                     KLVNEEVENNAATDKAPSTHTSPVVPVTTPGTKPDLNASFVSANAEQFYQYQPSEIIL
                     SEGRLVDSQGYGVAGVNYYTNSGRGVTGENGEFSFSWGETISFGIDTFELGSVRGNKS
                     TIALTELGDEVRGANIDQLIHRYSTTGQNNTRVVPDDVRKVFAEYPNVINEIINLSLS
                     NGATLDEGEQVVNLPNEFIEQFKTGQAKEIDTAICAKTDGCNEARWFSLTTRNVNDGQ
                     IQGVINKLWGVDTNYKSVSKFHVFHDSTNFYGSTGNARGQAVVNISNAAFPILMARND
                     KNYWLAFGEKRAWDKNELAYITEAPSLVEPENVTRDTATFNLPFISLGQVGEGKLMVI
                     GNPHYNSILRCPNGYSWNGGVNKDGQCTLNSDPDDMKNFMENVLRYLSDDKWTPDAKA
                     SMTVGTNLDTVYFKRHGQVTGNSAAFDFHPDFAGISVEHLSSYGDLDPQEMPLLILNG
                     FEYVTQVGNDPYAIPLRADTSKPKLTQQDVTDLIAYLNKGGSVLIMENVMSNLKEESA
                     SGFVRLLDAAGLSMALNKSVVNNDPQGYPNRVRQQRATGIWVYERYPAVDGALPYTID
                     SKTGEVKWKYQVENKPDDKPKLEVASWLEDVDGKQETRYAFIDEADHKTEDSLKAAKE
                     KIFAAFPGLKECTNPAYHYEVNCLEYRPGTGVPVTGGMYVPQYTQLSLNADTAKAMVQ
                     AADLGTNIQRLYQHELYFRTNGRKGERLSCVDLERLYQNMSVWLWNDTSYRYEEGKND
                     ELGFKTFTEFLNCYANDAYAGGTKCSADLKKSLVDNNMIYGDGSSKAGMMNPSYPLNY
                     MEKPLTRLMLGRSWWDLNIKVDVEKYPGAVSEEGQNVTETISLYSNPTKWFAGNMQST
                     GLWAPAQKEVTIKSNANVPVTVTVALADDLTGREKHEVALNRPPRVTKTYSLDASGTV
                     KFKVPYGGLIYIKGNSSTNESASFTFTGVVKAPFYKDGAWKNDLNSPAPLGELESDAF
                     VYTTPKKNLNASNYTGGLEQFANDLDTFASSMNDFYGRDSEDGKHRMFTYKNLPGHKH
                     RFANDVQISIGDAHSGYPVMNSSFSPNSTTLPTTPLNDWLIWHEVGHNAAETPLTVPG
                     ATEVANNVLALYMQDRYLGKMNRVADDITVAPEYLEESNGQAWARGGAGDRLLMYAQL
                     KEWAEKNFDIKKWYPDGTPLPEFYSEREGMKGWNLFQLMHRKARGDEVSNDKFGGKNY
                     CAESNGNAADTLMLCASWVAQTDLSEFFKKWNPGANAYQLPGASEMSFEGGVSQSAYN
                     TLASLKLPKPEQGPETINKVTEHKMSVE"
     gene            complement(105770..107452)
                     /gene="glcA"
                     /locus_tag="RN951_000348"
     CDS             complement(105770..107452)
                     /gene="glcA"
                     /locus_tag="RN951_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate permease GlcA"
                     /protein_id="HDX2525412.1"
                     /translation="MVTWTQMYMPMGGLGLSALVALIPIIFFFVALAVLRLKGHVAGA
                     ITLILSILIAIFAFKMPIDMAFAAAGYGFIYGLWPIAWIIVAAVFLYKLTVASGQFDI
                     IRSSVISITDDQRLQVLLIGFSFGALLEGAAGFGAPVAITGALLVGLGFKPLYAAGLC
                     LIANTAPVAFGALGVPILVAGQVTGIDPFHIGAMAGRQLPFLSVLVPFWLVAMMDGWK
                     GVKETWPAALVAGGSFAVTQFFTSNYIGPELPDITSALVSIVALALFLKVWRPKNTET
                     AISMGQSAGAMVVNKPSSGGPVPSEYSLGQIIRAWSPFLILTVLVTIWTMKPFKALFA
                     PGGAFYSLVINFQIPHLHQQVLKAAPIVAQPTPMDAVFKFDPLSAGGTAIFIAAIISI
                     FILGVGIKKGIGVFAETLISLKWPILSIGMVLAFAFVTNYSGMSTTLALVLAGTGVMF
                     PFFSPFLGWLGVFLTGSDTSSNALFGSLQSTTAQQINVSDTLLVAANTSGGVTGKMIS
                     PQSIAVACAATGMVGRESELFRYTVKHSLIFASVIGVITLLQAYVFTGMLVS"
     gene            complement(107807..109978)
                     /gene="glcB"
                     /locus_tag="RN951_000349"
     CDS             complement(107807..109978)
                     /gene="glcB"
                     /locus_tag="RN951_000349"
                     /EC_number="2.3.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate synthase G"
                     /protein_id="HDX2525413.1"
                     /translation="MSQTITQGRLRIDANFKRFVDEEVLPGTGLDAAAFWRNFDEIVH
                     DLAPENRQLLAERDRIQAALDEWHRSNPGPVKDKAAYKSFLRELGYLVPQLERVTVET
                     TGIDSEITSQAGPQLVVPAMNARYALNAANARWGSLYDALYGSDIIPQEGAMVSGYDP
                     QRGEQVIAWVRRFLDESLPLENGSYQDVVAFKVVDKQLRIQLKNGKETTLRTPAQFVG
                     YRGDAAAPTCILLKNNGLHIELQIDANGRIGKDDPAHINDVIVEAAISTILDCEDSVA
                     AVDAEDKILLYRNLLGLMQGTLQEKMDKNGRQIVRKLNDDRQYTAADGSEISLHGRSL
                     LFIRNVGHLMTIPVIWDSEGNEIPEGILDGVMTGAIALYDLKVQKNSRTGSVYIVKPK
                     MHGPQEVAFANKLFTRIETMLGMAPNTLKMGIMDEERRTSLNLRSCIAQARNRVAFIN
                     TGFLDRTGDEMHSVMEAGPMLRKNQMKSTPWIKAYERNNVLSGLFCGLRGKAQIGKGM
                     WAMPDLMADMYSQKGDQLRAGANTAWVPSPTAATLHALHYHQTNVQSVQANIAQTEFN
                     AEFEPLLDDLLTIPVAENANWSAQEIQQELDNNVQGILGYVVRWVEQGIGCSKVPDIH
                     NVALMEDRATLRISSQHIANWLRHGILTKEQVQASLENMAKVVDQQNAGDPAYRPMAG
                     NFANSCAFKAASDLIFLGVKQPNGYTEPLLHAWRLREKESH"
     gene            complement(110000..110404)
                     /locus_tag="RN951_000350"
     CDS             complement(110000..110404)
                     /locus_tag="RN951_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein GlcG"
                     /protein_id="HDX2525414.1"
                     /translation="MKTKVILSQQMASAIIAAGQEEAQKNNWSVSIAVADDGGHLLAL
                     SRMDDCAPIAAYISQEKARTAALGRRETKGYEEMVNNGRTAFVTAPLLTSLEGGVPVV
                     VDGQIIGAVGVSGLTGAQDAQVAKAAAAVLAK"
     gene            complement(110409..111632)
                     /gene="glcF"
                     /locus_tag="RN951_000351"
     CDS             complement(110409..111632)
                     /gene="glcF"
                     /locus_tag="RN951_000351"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcF"
                     /protein_id="HDX2525415.1"
                     /translation="MQTQLTEEMRQNARALEADSILRACVHCGFCTATCPTYQLLGDE
                     LDGPRGRIYLIKQVLEGNEVTLKTQEHLDRCLTCRNCETTCPSGVRYHNLLDIGRDIV
                     EQKVKRPLPERILREGLRQVVPRPAVFRALTQVGLVLRPFLPEQVRAKLPAETVKAKP
                     RPPLRHKRRVLMLEGCAQPTLSPNTNAATARVLDRLGISVMSANEAGCCGAVDYHLNA
                     QEKGLARARNNIDAWWPAIEAGAEAILQTASGCGAFVKEYGQMLKNDALYADKARQVS
                     ELAVDLVELLREEPLEKLAVRGDKKLAFHCPCTLQHAQKLNGEVEKVLLRLGFTLTDV
                     PDSHLCCGSAGTYALTHPDLARQLRDNKMNALESGKPEMIVTANIGCQTHLASAGRTS
                     VRHWIEIVEQALEKE"
     gene            complement(111643..112695)
                     /gene="glcE"
                     /locus_tag="RN951_000352"
     CDS             complement(111643..112695)
                     /gene="glcE"
                     /locus_tag="RN951_000352"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcE"
                     /protein_id="HDX2525416.1"
                     /translation="MLRECDYSQALLEQVNQAISDKTPLVIQGSNSKAFLGRPVTGQT
                     LDVRCHRGIVNYDPTELVITARAGTPLVAIEAALESAGQMLPCEPPHYGEEATWGGMV
                     ACGLAGPRRPWSGSVRDFVLGTRIITGAGKHLRFGGEVMKNVAGYDLSRLMAGSYGCL
                     GVLTEISMKVLPRPRASLSLRREISLQEAMNEIAQWQLQPLPISGLCYFDNALWIRLE
                     GGEGSVKAARELLGGEEVAGQFWQQLREQQLPFFSLPGTLWRISLPSDAPMMDLPGEQ
                     LIDWGGALRWLKSTAEDNQIHRIARNAGGHATRFSAGDGGFAPLSAPLFRYHQQLKQQ
                     LDPCGVFNPGRMYAEL"
     gene            complement(112695..114194)
                     /gene="glcD"
                     /locus_tag="RN951_000353"
     CDS             complement(112695..114194)
                     /gene="glcD"
                     /locus_tag="RN951_000353"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcD"
                     /protein_id="HDX2525417.1"
                     /translation="MSILYEERLDGALPDVDRTSVLMALREHVPGLEILHTDEEIIPY
                     ECDGLSAYRTRPLLVVLPKQMEQVTAILAVCHRLRVPVVTRGAGTGLSGGALPLEKGV
                     LLVMARFKEILDINPVGRRARVQPGVRNLAISQAVAPHNLYYAPDPSSQIACSIGGNV
                     AENAGGVHCLKYGLTVHNLLKIEVQTLDGEALTLGSDALDSPGFDLLALFTGSEGMLG
                     VTTEVTVKLLPKPPVARVLLASFDSVEKAGLAVGDIIANGIIPGGLEMMDNLSIRAAE
                     DFIHAGYPVDAEAILLCELDGVESDVQEDCERVNDILLKAGATDVRLAQDEAERVRFW
                     AGRKNAFPAVGRISPDYYCMDGTIPRRALPGVLEGIARLSQQYDLRVANVFHAGDGNM
                     HPLILFDANEPGEFARAEELGGKILELCVEVGGSISGEHGIGREKINQMCAQFNSDEI
                     TTFHAVKAAFDPDGLLNPGKNIPTLHRCAEFGAMHVHHGHLPFPELERF"
     gene            114445..115209
                     /gene="glcC"
                     /locus_tag="RN951_000354"
     CDS             114445..115209
                     /gene="glcC"
                     /locus_tag="RN951_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GlcC"
                     /protein_id="HDX2525418.1"
                     /translation="MKDERRPICEVVAESIERLIIDGVLKVGQPLPSERRLCEKLGFS
                     RSALREGLTVLRGRGIIETAQGRDSRVARLNRVQDTSPLIHLFSTQPRTLYDLLDVRA
                     LLEGESARLAATLGTQADFVVITRCYEKMLAASENNKEISLIEHAQLDHAFHLAICQA
                     SHNQVLVFTLQSLTDLMFNSVFASVNNLYHRPQQKKQIDRQHARIYNAVLQRLPHVAQ
                     RAARDHVRTVKKNLHDIELEGHHLIRSAVPLEMNLS"
     gene            complement(115216..116358)
                     /locus_tag="RN951_000355"
     CDS             complement(115216..116358)
                     /locus_tag="RN951_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001327865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDX2525419.1"
                     /translation="MECDLLMIKIEKVINKNDLKAFIAFPSSLYPDDPNWIPPLFIER
                     NEHLSAKNPGTDHIIWQAWVAKKAGQIVGRITAQIDTLHRERYGEDTGHFGMIDAIDD
                     PQVFAALFGAAEAWLKSQGASKISGPFSLNINQESGLLIEGFDTPPCAMMPHGKPWYA
                     AHIEQLGYHKGIDLLAWWMQRTDLTFSPALKKLMDQVRKKVTIRCINRQRFAEEMQIL
                     REIFNSGWQHNWGFVPFTEHEFATMGDQLKYLVPDDMIYIAEIDSAPCAFIVGLPNIN
                     EAIADLNGSLFPFGWAKLLWRLKVSGVRTARVPLMGVRDEYQFSRIGPVIALLLIEAL
                     RDPFARRKIDALEMSWILETNTGMNNMLERIGAEPYKRYRLYEKQI"
BASE COUNT        27658 a        31772 c        29196 g        27782 t
ORIGIN      
        1 gcagatgtat tacacggtat tgatgccacg ccgtgggcgt tcagtccgtg gatggtgatg
       61 caggcgacaa atcgcgaagc cagaaaacga ttatctgcat ttacccagct taaataaaaa
      121 aaccccgaca tttgccgggg ttgtgagcat aacgtaatgc ttattttacc ggacgcatcg
      181 ccgggaacag aataacgtcg cggatggtat ggctgttggt gaacagcatt accatacggt
      241 cgataccaat tcccagacct gctgtcggcg gtaagccatg ttccagtgcg gtgacgtaat
      301 cttcatcgta gaacatcgct tcgtcgtcac ctgcgtcttt cgcggcaacc tgatccagga
      361 agcgttgcgc ctgatcttcc gcgtcattca gctcgctaaa gccgttaccg atttcacgac
      421 caccaatgaa gaactcaaag cggtctgtga tttccgggtt aacgtcgtta cgacgcgcca
      481 gcggagaaac ttctgccgga tattcagtaa tgaaggtcgg ctgaatcaga tgtgcttctg
      541 ccacttcttc gaagatctcg gtaacgatac ggcccagacc ccagctcttc tcaacgtgga
      601 tgccgataga ttcagcaatt gctttcgcag agtcgaagtt gtccagatcc gccatgtcgg
      661 tttccgggcg atatttcttg atcgcttcac gcatggtcag tttttcgaac ggtttaccga
      721 agtccagcgt cacgtcgccg taggtcactt ccgtcttacc gagaatatcc tgtgccagag
      781 tacggaacag cgattcggtc agctcgatca gatctttgta atctgcgtaa gccatgtaga
      841 gttccatcat ggtgaactct gggttatgac gtacggaaat accttcgtta cggaagttac
      901 ggttgatttc gaatacacgc tcgaagccac caaccaccag acgcttgagg tacagttccg
      961 gcgcgatacg caggtacatg tcgagatcca gcgcgttatg gtgggtgata aacggacgcg
     1021 cagcggcacc gccagggatc acctgcatca tcggcgtttc aacttccata aagccgcggt
     1081 tcaccatgaa ctggcgaata ccagagagga tctgcgagcg cactttaaag gtgttgcggg
     1141 attcatcgtt ggagatgaga tcgagataac gctgacgata gcgcgcttcc tgatcctgca
     1201 agccgtggaa tttatccggc agcggacgca gtgctttggt cagcagacgc aactcggtgc
     1261 agtggataga cagttcgccg gttttggttt tgaacagctt acctttcgcg ccgaggatgt
     1321 cgccgaggtc ccattttttg aactgctcgt tataaacgcc ttccgggaga tcgtcacggg
     1381 caacgtacag ctgaatgcga ccgccaacgt cctgcagggt aacgaaagac gctttaccca
     1441 taatacgacg ggtcatcatg cggccagcaa cggcgacttc gatgttcagc gcttccagtt
     1501 cttcgttctc tttgccgtcg aattctgcgt gcaattggtc agaggtatga tcgcgacgga
     1561 aatcgttcgg gaaggcaatc ccctgctcgc gcaggttcgc cagcttctca cgacgcgttt
     1621 tcagttcatt gttaagatcg actaccgcgt cagcgccctg tgcgtgttgt tcagacatgt
     1681 tggttcctca taaccctgct ttcaaacttg cttcgataaa ttgatccagg ctgccgtcca
     1741 gcacggcctg cgtgttgcgg gtttctaccc cggtgcgcag atctttaatg cgggagtcat
     1801 caaggacata agaacgaatc tggctgcccc agccgatgtc ggatttgtta tcttccatcg
     1861 cctgtttctc ggcatttttc ttctgcatct ccagttcata aagcttcgct ttcatctgct
     1921 tcatggcctg atctttgttc ttgtgctggg aacggtcgtt ctggcactgg gtcacgatcc
     1981 cggtcgggat gtgggtaata cgcaccgcag attcggtacg gttaacgtgc tgaccgcccg
     2041 cgccggacgc gcgataaacg tcaatgcgca gatccgccgg gttgatttcg atatcaatat
     2101 catcatcaac ttccggataa acaaacgcgg agctgaacga cgtgtggcga cgaccgccgg
     2161 agtcaaacgg gcttttacgc accaggcggt gaacgccggt ttctgtacgc agccagccgt
     2221 aagcgtaatc gccggagatt ttgatcgtca cggatttaat acccgccact tcaccttccg
     2281 actcttcgat gatttcagtt ttgaaaccac gcgattctgc ccagcgcaga tacatacgct
     2341 caagcatgct cgcccagtcc tgtgcttccg taccgccaga ccccgcctga atatcgaggt
     2401 agcagtcggc gctgtcatat tcgccagaga acatacggcg gaactcaagc tgcgccagtt
     2461 tttcttccag ggcgtcgagt tcagcaacgg cttcgttaaa ggtttcttcg tcgtcagctt
     2521 ctacagccag ttccagcaga ccagaaacat cttccagccc ctgtttcatt tggtcgaggg
     2581 tgtcgacaac ggcttcgagg gaggaacgct ctttacccag cgcctgtgcg cgttcgggtt
     2641 cgttccagac atccggctgt tccagctcgg cgtttacttc ttccagacgc tctttcttgg
     2701 cgtcgtagtc aaagataccc cctaagaacg tcggagcgtt ccgtgaggtc ctgaatgcga
     2761 ttatttaccg gattaatttc aaacatggtc tgatttcttt tattgagcta gtcaaaatgc
     2821 ggtgataaga gcgggattgt acccaatcca cgctcttttt tatagagaag atgacgctaa
     2881 attggccaga tattgtcgat gataatttgc aggctgcggt tgccgcgaaa ctcgttgata
     2941 tcgagcttat aagccagttg cacttcgcgc acgccgttat ccggccagag ggcggtatcg
     3001 acattaaaag caataccatc cagcagtgga ccgccgccga ccggttcgac catcaccttc
     3061 aaatgacgtt cgcccaccag ccgctgttgc agcagacgga aatgaccgtc aaacagcggc
     3121 tccgggaaca tctgccccca cgggccagca tcgcgcagca actgcgccac ttccatggtc
     3181 atttcggccg ggcttaacgg accgtctgac accacttcgc cttgcaatag cgaagggtcc
     3241 agccactctg taaccagttc gccaaaccgt tgttgaaaga gttcgaattt atcctcttcc
     3301 agcgacaaac ccgccgccat cgcatgaccg ccaaacttca gtatcatgcc agggtagagt
     3361 gtgtctaatc gctccagtgc atcacgcata tgcagcccct gaatggagcg acctgaacct
     3421 ttcagcgtac catcacctgc tggcgcaaag gcgataaccg gacggtgaaa acgctctttg
     3481 atgcgcgaag ccagaatacc gacaacgccc tgatgccatt cggggtgata cattgccagc
     3541 ccgccgggta gcgtgtcgcg acttcgctcc agtttctcgc acagggtcag ggcttcaact
     3601 tgcattcctt gttcgatctc ttttcgcgtc tggtttagcg catcgagttc atttgccagc
     3661 acgcgcgctt cgccgatgtt gtcgcacagc aagagcgcca caccgacgga catatcgtcc
     3721 agtcgtccgg cagcattgag acgtggcccc agcgcaaaac ctaaatcgct ggcggcgagt
     3781 ttttgtgcat cacggtttgc cacttccagc agcgctttaa tccctggacg gcactttccg
     3841 gcacggatgc gactcatccc ctgccaggtc agaatgcgat tattagcgtc cagcggcacg
     3901 acgtccgcca ctgttcccag cgcgaccaga tccagcagtt ctgccaggtt aggaattgcg
     3961 atgccacgct catcaaacca gccctgatcg cgcaaaaagg tgcgcagcgc cagcatcaga
     4021 taaaacgcca cacccacgcc tgccagtgat ttcgacggga aattacagtc gcgcaagtta
     4081 gggttaatga tcgcttccgc cgcgggtaat gtttcgcctg gcaaatggtg atcggtaaca
     4141 ataaccggaa tgcccaacga gcgagcgtgt acaacccccg catgggagga aataccgtta
     4201 tccaccgtga caattaactg cgcgccacgg gcatgggcct gatcgaccac ttccgggctt
     4261 aagccgtaac cgtcttcgaa acggtttggt accaggtagt cgatattgct gcaaccaagc
     4321 gagcgcatcg ccagcacgct tagagccgtg ctggtcgcgc cgtcggcgtc gaaatcaccg
     4381 accacaataa tccgcgttcc ttcgcgaaaa gcgttgtaaa ggatctcaac ggccttttcg
     4441 acgccgctca gttgctgcca gggcaacata cctttaacac tgcgttccag ttcttgcgca
     4501 ctgcgcacgc cccggctggc gtataaacgg cgcagcaagg gaggcaattc agcgggcaag
     4561 tctgccgttt catcgacttc acggcgacga agttgtatct gttgtttcac gcgaattatt
     4621 taccgctggt cattttttgg tgttcgtcaa ggaattcttt catctctttc ggcggctggt
     4681 aacccggaac aagtgtgcca ttgctcagca caactgccgg agtaccgcta acgccaagct
     4741 ggacgccaag tgcgtaatgg tcggcaatat ccacgtcgca gctggctggt gcgacgcttt
     4801 tacctgccat cacatcatca aacgctttgt ttttatcttt cgcacaccag atagctttca
     4861 tttctttctc tgcatcgctg tccagcccct ggcgcgggaa agcaagataa cgcacggtga
     4921 tccccagcgc gttatagtct gccatttgct catgcagttt gtggcagtaa ccacaggtaa
     4981 tatcagtaaa cacggtgatg acgtgttttt cctgcggcgc tttataaacg atcatctctt
     5041 tttcaagcgc attcaactgc tttaacagca tcttattggt gacattgacc ggagccgtgc
     5101 cgctaacgtc atacattggc ccctgaatga tatgtttacc atcatcggtg atgtacaaca
     5161 cgccgctgtt agtcagaact gtcttcatgc cagctacggg cgcgggctga atatcgctgc
     5221 ttttgatgcc cattttggct aacgtttgtt gaattgccgc gtcatcagcc tgagcaaaac
     5281 ctgaaaacgc cgctaacaaa gtaaacaaca taaaaccttt cttcataaat cttcccgttc
     5341 ttttcagaca tcacgcccgc gggtgatgct gttgatgaag ttgccgcaga cgctcggtag
     5401 cgacatgcgt ataaatttgc gtggtggaaa gatcgctgtg gcccagtagc atctgcacca
     5461 cgcgtaaatc cgcaccatga tttaataaat gagtggcaaa agcgtgacgc aacacatgcg
     5521 gtgacagctt ttcgctgtcg atacccgcca gcacagcata atgtttaatg cggtgccaga
     5581 aggtctgtcg cgtcatctgc tgcgcacgct ggctgggaaa caacacgtca attgacacac
     5641 cattcagcag ccacggacgc ccatgttcca gataggtttc cagccagtaa accgcctctt
     5701 cacctaacgg taccaggcgc tctttgttgc ctttaccaat gacccgcact acgccctgac
     5761 gcaggctgat atcactcatt gtcagtccga ccagttcaga gacacgcagc ccggtagcat
     5821 acaacacttc aagcatggct ttatcgcgta gctccagtgg ctgatcaatt aatggtgcct
     5881 gtaataaacg ttcgacctgc gcttcgctta aatcttttgg caaacgctgg ggcaatttcg
     5941 gtgaagcgag atgcgcactg ggatcgtctt cacgaaactt ttcgcgataa agatactgga
     6001 acaatcggcg cactgcactc agcaaacgcg ctgagctggt ggctttatac ccgccctcca
     6061 gccgttctgc cagtaatgcc tgcaaatcgt cactttgcgc cgtcgccagc gtcaacccgc
     6121 ggtgatgcaa ccactccacc atcattgaca gatcgcgacg gtaagcgttc aacgtatttt
     6181 cagccagatt tttttccagc cacagagcat caagaaactg ctcgatgcgt gccagatcct
     6241 gtttcacttg cgccccttat ggtcactcat ttgatccatt atgccttatt gtgccgtgac
     6301 taaagcgatt ctgatacact agcagcaaaa gccacagcag aatcgagaag cttacgttat
     6361 gaatatgggt cttttttacg gttccagcac ctgttacacc gaaatggcgg cagaaaaaat
     6421 ccgcgatatt atcggcccag aactggtgac cttacataac ctcaaggacg actccccgaa
     6481 attaatggag cagtacgatg tgctcattct gggtatcccg acctgggatt ttggtgaaat
     6541 ccaggaagac tgggaagccg tctgggatca gctcgacgac ctgaaccttg aaggtaaaat
     6601 tgttgcgctg tatgggcttg gcgatcaact gggatacggc gagtggttcc tcgatgcgct
     6661 cggtatgctg catgacaaac tctcgaccaa aggcgtgaag ttcgtcggct actggccaac
     6721 ggaaggatat gaatttacca gcccgaaacc ggtgattgct gacgggcaac tgttcgtggg
     6781 tctggcgctg gatgaaacta accagtatga ccttagcgac gagcgtattc agagctggtg
     6841 cgagcaaatc ctcaacgaaa tggcagagca ttacgcctga tctcactgac ggcttagcgc
     6901 atatgctttg ccgtcatctt tatctttgcg tctcttgttg caacaaaatc cgccgtaaat
     6961 cccgccattc ggcttcgtcc atgctgtcgg ctgccagcca taaatgttgc cgtttaccgc
     7021 catcagaacg taaacgcagc atcatgccgc tcttaatcat ccacggtgct ttgacgatgc
     7081 accactcctg cccttgccaa cgcaaacgcc cgtccatcaa caagcgaatt tccccctggc
     7141 gagcattaat acgccgctgg ctgcgaacgc aatcaaacac caccagcgaa agtaacacca
     7201 tccataacgg ggtgtaactg agtggccagg gcatgagtaa aataacagcg gcaaccagcc
     7261 catgaatcag caaggaaagc cactgtgcgc gccaggagac gcgcaaatca gattgccaca
     7321 ggaccacgtt cccggttccg tgtctggatg agtcggacca tcatttccag ttctgcatcg
     7381 gccggtttac cgtgattcat cagccagtta aacaggtccg gatcgtcaca ttccagcaga
     7441 cgaataaaga tgcgtttttc gtcatcgctt aagctgtcgt actcatgttc gaaaaacggc
     7501 atgattgaaa tatcgagttc gcgcatacca cggcggcatg cccaatgaat gcgggctttg
     7561 ttgttaatgt ccatcttctt cctgtctcac gaaaatccag tacccggcta ttgtaacgtg
     7621 tttttcgcct tcttttacgg gaatatcagt aaacaccatc gcgatcgcga aattaattca
     7681 caacaattca atggcttcat ttttttggaa gtcgcctcgc agaaggcaca gatcgcgtag
     7741 tgaaagcact tgcattgcct catagctctt ttaccattag tcattaatac gccgttaagc
     7801 aactcaggac tctattatgg cttttacacc ttttcctccc cgtcagccta cggcttctgc
     7861 ccgtttaccg ctgacgctga tgacgcttga tgactgggcg cttgccacca ttactggcgc
     7921 ggacagcgaa aaatatatgc agggtcaggt gacagcagat gtcagccaga tggcagaaga
     7981 tcagcacctg ctcgccgccc attgcgacgc caaaggtaaa atgtggagca atttacgtct
     8041 gttccgcgac ggcgatggct ttgcatggat tgaacggcgc agcgtgcgtg aaccgcagct
     8101 gactgaactg aaaaaatatg cggtattctc taaagtgacc atcgcgccag acgacgagcg
     8161 tgtgctgctt ggtgttgccg gttttcaggc gcgcgccgcg ctggcaaatc tctttagtga
     8221 actgccttcg aaagaaaaac aggtagttaa agaaggcgcg accactttgc tatggtttga
     8281 acacccggca gaacgtttcc tgatcgtaac cgatgaagct actgctaata tgctgaccga
     8341 taaactgcgc ggtgaagcgg aactgaacaa tagccaacag tggctggcat taaacattga
     8401 agcgggtttc ccggtgattg atgccgccaa cagcgggcag tttatcccac aggcgaccaa
     8461 cctccaggcg ctgggcggca tcagctttaa aaaaggctgc tataccggac aagagatggt
     8521 ggcgcgagca aaattccgtg gtgccaataa acgtgcgctc tggttgctgg caggtagcgc
     8581 cagccgactg ccggaagctg gtgaagactt agagctgaaa atgggcgaga actggcgtcg
     8641 taccggtacg gtgctggctg cggtaaaact ggaagatggt caggtcgtgg tacaggtcgt
     8701 catgaataac gatatggaac cggatagcat cttccgcgta cgcgacgatg cgaatacact
     8761 gcatatcgag ccgctgccgt attcgctcga agagtaaatc tctttatcgc atcaggcatt
     8821 tatcgcctga tgcgacgctg gcgcgtctta tcaggcctac aaaggcatac ccattacgcc
     8881 tgcccaatat acaaatagat cgccagaaag tggcacacac taccgccgag cacgaagccg
     8941 tgccagatgg catggttgta tggaatgcgt ttgcagacgt agaaaatcac cccgagcgaa
     9001 taaaccacgc cgcctaccgc cagtaaggta acgctgcccg ccgcgagctt aactgccatt
     9061 tcataaatta ccaccagcga cagccagccc atcgccagat aggtcaccag agataaaatt
     9121 ttgaatcggt gcgcgatggt cagtttaaac agaataccca gcaatgccag gctccagata
     9181 acaatcatca acccgcgcgc taacggagaa tccagcccca ccagcaaaaa cggcgtgtag
     9241 gttccggcaa tcaacaggta aatagcgcaa tggtcaaatt tcttcagcca catttttgcc
     9301 cgttgatgag gaatggcgtg atagagcgtc gaagcgagga acagcaggat catactgccg
     9361 ccatagaggc tgtaactggt tatcgctgtg gcgctggcat tgagatccac cgcctgaacc
     9421 agtagcaaca ccagcccaac gataccaaac accaacccaa tgccgtgact gacgctgttg
     9481 gcaatttcct ctgccagcga atatccctgc ttaatgaggg gcttctgaac cataacttac
     9541 tccggagaaa cgtacacgca catgtatacc tctccagcgt aactgagaat agttccagtg
     9601 aacacctgtt agctaaaata aattctgatt tgagactaat ctcctaaaaa tcatgaaatt
     9661 aaatgcgaaa tttcaactaa caggcgtgag ttcaatttaa agacatttaa attcaatcac
     9721 ataaaactgt gtctgaccgg gatagatgtc ggcaatgacc tttatcagtt cagtcagggt
     9781 catattttcc tgctctgcat gtttttccgt cagcgtatcc agcgttacgg ttgaggttgc
     9841 ggtgacttca atcgtgcaaa aataaccgtc atcttcaaaa cgcccgacac gaagcacatc
     9901 acccgttttg aagtgcgatt cagactcgtc gcggatggtg atggttttac gcccagccag
     9961 aatgtcatcc tggaaacgtt gaaaaaaagt gatgtcgttt ggctgcatgg tactatttcc
    10021 tgtaagaatt gactcatctg gagcctatga tagtgaaaaa actcacctta ccgaaagatt
    10081 tcttatgggg cggcgcagtt gccgctcatc aggtcgaagg cggctggaac aaaggcggca
    10141 aagggccgag catttgtgac gttctgaccg gtggcgcaca cggcgtgccg cgcgaaatca
    10201 ccaaagaagt cttgccaggc aaatactatc caaaccatga agccgttgat ttttatggtc
    10261 actacaagga agacatcaag ctatttgccg aaatgggctt caaatgtttt cggacttcca
    10321 tcgcctggac gcgtattttt ccaaaaggtg atgaagctca gccaaacgaa gaagggctga
    10381 agttctacga tgatatgttc gatgaactgc tgaaatacaa catcgaaccg gtgatcaccc
    10441 tctcccactt tgaaatgccg ctgcatctgg tgcagcaata cggtagctgg accaaccgta
    10501 aagtggttga tttctttgtc cgtttcgcgg aagtggtgtt tgaacgctat aagcataaag
    10561 tcaaatactg gatgaccttc aacgaaatta acaaccagcg taactggcgt gcaccgctgt
    10621 tcggttactg ctgctccggc gtggtttata ccgagcatga gaacccggaa gagacgatgt
    10681 atcaggtgct gcatcaccag tttgtcgcca gcgccctggc ggtgaaagct gcgcgtcgca
    10741 ttaacccgga gatgaaagtc ggctgtatgc tggcgatggt gccgctctat ccctactgct
    10801 gtaacccgga cgatgtgatg ttcgctcagg agtcgatgcg cgaacgctac gtctttaccg
    10861 atgtgcagct acgcggctat tacccgtcct atgtgttgaa cgagtgggag cgtcgcggat
    10921 ttaacatcaa aatggaagac ggcgatctcg atgtactgcg tgaaggcacc tgcgattatc
    10981 ttggtttcag ctattacatg accaacgcag tgaaggccga aggcggcacc ggcgatgcga
    11041 tctctggttt cgaaggcagc gtaccgaacc cgtatgttaa agcgtctgac tggggctggc
    11101 agattgatcc agtaggtctg cgctatgccc tttgcgaact gtatgagcgt tatcagaggc
    11161 cgctgtttat tgtcgaaaac ggttttggcg cttacgacaa agtggaagaa gatggcagca
    11221 tcaacgacga ctaccgcatt gactacctgc gcgcccatat cgaagagatg aaaaaagcgg
    11281 tgacttacga tggcgtggat ctgatgggct acacaccgtg gggctgcatc gactgcgtat
    11341 cgttcaccac cgggcagtac agcaaacgct acggctttat ctatgtgaat aaacatgacg
    11401 acggtgctgg cgatatgtcg cgttcacgta agaagagctt taactggtac caagaggtga
    11461 ttgccagcaa cggcgagaag ctttaagtcg atgaagtacc ggatgcaata cttgttgcat
    11521 ccggtcagac aacttccctg ttttatttcc cgcccgccaa atcgataaaa cttcccgtga
    11581 cgtaagaggc tttatcactt agtagccaga caatggcctg cgcgacctct tctgcctgtc
    11641 caccacgctg catggggatg ttcgacttaa cgcgatcgac gcgtccaggc tcgccgccgc
    11701 tggcgtgcat ttcggtataa ataaaccctg gccgcacgca gttaacgcgg atcccctgcg
    11761 cggcgacttc cagcgatagt ccggtggtta acgtatcaat cgcccctttc gatgccgcgt
    11821 aatcaacata ttcccctggc gaacccaacc gtgaggccac cgaagagaca ttgacgatag
    11881 cgccgccact gccaccattt ttaagcgcca tgcgttttac cgcctcgcgg cagcagagaa
    11941 aatatcccgt cacgttggtg gaaagtactc ggttgattcg ctctgcggta aggttttcaa
    12001 cggtgcactg ggtaaacaag atcccggcgt tattgaccag cgctgctagc ggttcatcgt
    12061 gctgatcgat tgctgtaaac attgcgatga cctgattttc atcgctgata tccgcctgga
    12121 gcacgaatgc cttgccaccg gcttgcgtga ttaagttcac cacttcctgc gccgcatgga
    12181 ggttttgttg ataattaacc gccaacgtat actcttcttt cgccaacagt aatgcagttg
    12241 cccgcccgat gccgcgactg ccaccggtca caagtgctat agccatttgt ttttccgaga
    12301 aaaattaatt cgttgacgta tctttgagat tgctaacaaa ctggctcaat cttcaatgtt
    12361 ggcacgcttt tcccctcgcc ctttcaggga gagggccggg gtgagggtaa atattcgcgc
    12421 cagtgccggc ctgttcccct caccctaacc ctctccccaa aggggggagg ggactgtctg
    12481 agcgcttttg tactttgtca tctgactaaa aaggcgccga agcgccttta gaagatagtc
    12541 gaatcagtga attactggta ttcgctaatc ggtacgcagg agcagaacag gttacggtcg
    12601 ccgtaaacat catccagacg tttcaccgtc ggccagtatt tgtctgccac acctgccggg
    12661 aatactgcaa cttcacggct gtacggatgc gcccactcgg cgaccagttc gttctgaatg
    12721 tgcggcgcgt tcaccagcgg gttatcttcc agcggccaga caccggcttt aacctggtcg
    12781 atttctgcgc ggatagccag catcgcgtcg ataaagcgat ccagttccac tttgctttca
    12841 gattcagtcg gttcaaccat cagcgtaccc gccaccggga acgacatggt cggcgcgtgg
    12901 aaaccgtagt cgatcaggcg cttggcaata tccagctcgc tgatgccggt ttcttctttc
    12961 agcgggcgaa tatcgagaat acattcgtgc gccacgcgac cgtcgcgacc ggtatacagc
    13021 accgggaagg catcctgcag gcggctggca atatagttgg cgttgaggat tgccacctgg
    13081 cttgcttttt tcagcccttc tgcgcccatc atgcggatgt acatccagct gattggcagg
    13141 atagaggcgc taccgaacgg tgccgcagaa actgcgccct gacgggttaa catgccttcg
    13201 atttgcacca cgctatgacc cggtacaaac ggtgccagat gcgctttcac accgatcggt
    13261 cccatacccg gaccaccacc gccgtgcgga atgcagaaag ttttatgcag gttgaggtgc
    13321 gaaacgtccg cgccaataaa gcccggcgag gtgatgccaa cctgggcgtt catgttcgcg
    13381 ccatcaaggt aaacctgacc gccgaactga tgcacgactt cacacacttc acggatcgtt
    13441 tcttcataca cgccgtgggt agaaggataa gtcaccatga tacaggagag gttatcgccc
    13501 gcctgttccg ctttcgcgcg cagatcagtc agatcgatgt tgccgttttt atcacacgcc
    13561 acaaccacca cctgcattcc tgccatatgt gcagaagcgg ggttagttcc gtgcgcagaa
    13621 gccgggatca ggcagatatc gcgatgccct tcgttgcggc tttcatgata atgacgaatc
    13681 gccagcaggc ccgcgtattc gccctgtgcg ccggagttcg gctgcataca aacggcgtcg
    13741 taaccggtca gtttcaccag ccagtcagcc agctgcgcaa tcatctgctg ataaccttca
    13801 gcctgttccg gcggacaaaa cgggtgcagt tcggcaaatt ccggccaggt gattgggatc
    13861 atctcggcgg cggcgttcag tttcatggtg caggaaccca gcgggatcat cgcctgattc
    13921 agcgccagat ctttacgctc cagcgagtgc atatagcgca tcatttcggt ttcgctgtgg
    13981 tagcgattaa acaccggatg ggtgaggatt tcgtcgtcgc gcagcatcgc aggctggata
    14041 gagcggctgt cgtgagccac gtctttgtcc agcgtgtcga tgtccaggcc gtggttatcg
    14101 cccagcagca cgttgaaaag ctgcattacg ttttcacgcg tggttgtttc atcaagggtg
    14161 atcccaaccg cgttcagaat atcgctacgc aggttgattt cagccgcttc ggcacgcgtc
    14221 agtacgcccg ctttgtcggc cacttccaca cacaaggtgt cgaaatagtg cgcatggcgc
    14281 agtttcagac ctttttgttg caggcccgcc gccaggatat cggtcagacg gtgaatgcgg
    14341 ttagcgatac gtttcaggcc aatcgggccg tgataaacgg catacaggct ggcgatgttt
    14401 gccagcagca cctgggaagt acaaatgttg gagttcgctt tctcacggcg aatatgttgc
    14461 tcgcgagtct gcatcgccat gcgcagcgcg gtattgccag ctgcatcttt cgatacaccg
    14521 ataatacggc ccggcattga gcgtttgtat tcatctttcg ccgcaaagaa ggccgcgtgt
    14581 gggccaccgt agcccatcgg cacgccgaag cgttgcgccg aaccaaaaac aatatccgcg
    14641 ccctgtttac ccggcgcagt taacagcacc agcgccataa tatcggcggc gacactgacc
    14701 acaattttgc gtgatttcag ttcgctaata agcgcggtgt agtcgtggat ttcaccggtt
    14761 gtgccaacct gctgtaacag cacgccgaag acgtcctgat ggtcgagcac tttttgcgcg
    14821 tcatcgacaa tcacttcaaa accaaaggtt tcggcacgag tacggaccac atccagcgtt
    14881 tgcggatgca catcggaagc cacgaagaag cggttggcat ttttcagttt gctgacgcgt
    14941 ttcgccatcg ccattgcttc ggcggcagcg gtggcctcgt ccagaagaga agcagaggcc
    15001 atatccagtc cagtcaaatc cagcgttacc tgctggaagt tgagcagtgc ttcaaggcgg
    15061 ccctgggaga cttcaggttg atacggagtg tacgcggtat accagcccgg attttccagc
    15121 atgttacgca ggataaccgg cggtagctgc acggcggtgt aacccatgcc gatgtaagac
    15181 gtgaagcgtt tattgcgact ggcaatagcc ttgagttctg ccagtgcggc gtattcggtc
    15241 gccggtgcgc caacctgcgg cggggtcgca agctgaatat ctttcggcac aatctggccg
    15301 gtcagcgcgt ttaacgattg tgcaccaacg gcattcagca tttcttgctg ttgcgcggcg
    15361 tccggtccga tatggcgttc aataaaagcg ccgctgtttt caagctggct taacgtctgt
    15421 gtcatgagcg atggttcctg aaacgtgcag tgaattgtga acctctctcc ttacgaagag
    15481 agtgagggtg aggcataaat tttcctcacc ctgatcctct cccgcagaag aggaataaag
    15541 ccgttactcg tcttctaaca atgcttcgta tgcggtcgca tccagcagtg attccagttc
    15601 gctttcatcg ctggctttga ttttaaagat ccagccacct gcatacggtt cgctgttcac
    15661 cagttccggg gaatcgctca gtgcgtcgtt taccgccacg atttcaccgc ttactggcgc
    15721 ataaatgtct gacgccgctt ttactgattc ggcaaccgcg cagtcatcgc ccgcgctaac
    15781 cgttgcgccc acttccggca ggtcaacaaa caccatatcg cctaacagct cctgggcatg
    15841 ttcggttata ccaacggtgt aagtgccgtc ggcttcttta cgcagccatt cgtgttcttt
    15901 gctgtatttc agttctgctg gtacgttgct catcaatcaa tctccaaaaa agtaaatcac
    15961 gcgacggctt taccgttacg cacaaaaaca ggtttcgtca ctttaaccgg catttcacgg
    16021 ttgcgaattt gcacaatcgc cgtttcgcca ataccttccg gcacgcgtgc cagcgcaatg
    16081 ctgtaaccca gcgtcgggga gaaagtcccg ctggtgataa tgccttcatg ctggttgccc
    16141 tgcgcatcgg taaaacgtac cggcagttca ttacgcagca cgcctttttc ggtcatcacc
    16201 agaccaacca gtttttctgt gccatgctca cgctgcactt ccagggcttc acgaccgatg
    16261 aagtcacgat ctgccggttc ccaggcgata gtccagccca tgttggcggc taacggagag
    16321 atggtttcgt ccatctcctg accataaaga ttcatgcccg cttccagacg cagcgtgtca
    16381 cgcgcgccca gaccgcatgg cttaacgccc gcttccacca gcgcacgcca gaaatcggcc
    16441 gctttttcat tgggcagcgc aatttcatag cccgcttcac cggtataacc agtggtggca
    16501 ataaacagat cgcccgcctg cacgccaaag aacggtttca tcccttccac cgcctgacgc
    16561 tgagcatcat taaacagtgt ggcagctttt gcctgcgcat tcggcccttg tacggcgatc
    16621 atggaaaggt catcacgaac ggtaatttcg atgccgaaag gttcagcgtg ttgggtaatc
    16681 caggagaggt ctttttcgcg ggtggcggag ttaacaacga ggcggaagaa atcttcagta
    16741 aagtagtaga cgatgaggtc atctatcaca ccgccagagg cattcaacat ccccgagtaa
    16801 agggctttgc cgcttttggt gagcttcgcc acatcgttcg ccagcagata acgcagaaac
    16861 tcccgggtgc ggctgccgcg aagatcgacg atggtcatat gtgacacatc aaacattccg
    16921 gcatcggtac gtaccgcatg atgttcgtcg atttgcgaac cgtaatgcag cggcatcatc
    16981 cagccgtgga aatccaccat gcgagcgccg caaagcgtgt gttgttcgta caaaggagtc
    17041 tgttgtgcca tcttgtcctc attgaataag cggggctgac aactttttca tggtgaaatt
    17101 atcactacga aacccagcat cggagccact cccggtcccc aacgcaatcg ttctctttta
    17161 cctgaactta ccaccgaaac agactgttaa ccataaggta aaattgatca tcacattagc
    17221 ttatggttaa aaaacgccaa aatcgcgaca gaataaaaaa ccaaaaaaca caccagtttc
    17281 tatataaaga tgatgccatt agaaagctaa tttgaataag gcaatattaa gagctaaaaa
    17341 aatgtcaaaa aacactaaat caaaaaataa tgacattaga aaatataatg cgaaaacgga
    17401 ggtgaaatta gtttatttca aatgaggaaa atctcccggc gaaaaaaccg ggagatgaaa
    17461 gtgtgatggg tatcaaataa acagcagaag agaaattttt aacgcagcca ttcaggcaaa
    17521 tcgtttaatc ccattgcctg gcggataagt tgtggtttaa cgccaggaag cgtgtcggcc
    17581 agtttcaaac caatatcacg cagcagtttt ttcgccggat tggtaccgga aaacagatcg
    17641 cggaatccct gcataccagc cagcatcagc gccgcactgt gcttgcggct acgctcatac
    17701 cggcgcaggt aaatgtactg cccgatgtct ttcccctgac gatgcaaccg tttcagttca
    17761 gcaatcagct ctgcagcatc cataaagccg agatttactc cctgccccgc cagcgggtga
    17821 atggtatgcg cggcgtcgcc caccagcacc agacggtgcg cggcaaactg gcgcgcataa
    17881 cgccccgtca gtgggaacac ctgacgcgcg ctctcaacct tgcataagcc caggcgatta
    17941 tcaaaagcga tatttaacgc gcgattaaat tcatcttcac ttgcctgctg catccgctgc
    18001 gcttcctctg gcgacagtga ccagacaatt gagcaaagat gcggatcgct aagcggtaaa
    18061 aaggccagaa tgccttcgcc atggaaaacc tgccgcgcca ccgcatcatg cggttcttcc
    18121 gtgcgaatgg tcgctaccag cgcgtgatgc tgataatccc agaaagtcag cggaatatct
    18181 gctttgttgc gcaaccagga attagcaccg tccgcgccaa tcaccagacg cgccgttaac
    18241 atgctgccat ctttcagcgt caggaaagtt tcattttctc cccaggcgac ctgctgtaat
    18301 tctgcggggg ccaacagagt gatatctgac gactgctgcg ctttgttcca cagcgcgtag
    18361 tgaatcactg agttttcaac gatatgccca agatggctat agcccatgct ttgatcgtca
    18421 aacgaaatgt gaccaaaact gtctttgtcc cacacttcca taccgtgata acaactggcc
    18481 ctacgagaga gaatgtcctg ccagacgcca agacgggtga gtaatttttc gctggcggca
    18541 ttgatagccg aaacgcgcag ttgtggtggt gcatccgccg ccagaggttc cggtacgcgc
    18601 tgctccagta cggcaacgcg taagccgctc ccctgtaagc cgcaggcaac cgccagcccc
    18661 accatgccgc caccaacaat ggctacatca acactttgca ttgtttattc cttaaaaccg
    18721 ccttcaacgc gccacccaac cgagggtgcg ctgcgccagc acatcgcgtg ccggggtgaa
    18781 taattccatc gtcatcagtc cgatgttgcg cccgacaacc agcggtgccc aacggttggc
    18841 aaaaagatgt accaggctgt ccgtgacgcc gatggttgct tcgcgatcgc tctgtcgacg
    18901 ctgttgatag cggcacaata tgccgtaatc accgatgtct tctccgcgct catgcgcctg
    18961 agttagggtt tccgcaaggc tcatgacatc tcgcataccg aggttaaacc cttgcccggc
    19021 aatcgggtgc agagtttgcg ccgcattgcc caccagcacg gtacgatggg taatagctct
    19081 ggcggcgcgg gttaacgcca acggataagc actgcgttta ccggcgtggg taatttttcc
    19141 aagtcgccag ccaaaggccg actggagttc acggcaaaac ttctcgtcgc tccacgacag
    19201 cacctcttcg cgccgttcca gtggatgaca ccagaccagc gaacagcgtc cgtcagacat
    19261 cggcaacatc gccagcgggc catgttgcgt gaagcgttca aaagcgcggc cttcgtgcgc
    19321 aacggaagtc gcaacgttgg caatcacggc cagttgttcg taaggctcct gctgccaatc
    19381 aacgccgcac gcggtggcta acgctgaatg ggtgccatca gcggctatca gcacgcggcc
    19441 cgtcagcatc tcgccgctct ccagcgtcac ttcaacgtga ctctgagtac gggcaacgtt
    19501 agctacgcga tcggggcaat gcagcattac gccaggtgct tttcgcagca atgcaaacag
    19561 ccgttgcccg acattatgca attcgacaac ctgccccagc gccgccagtt ggtaatcttc
    19621 tgcggcgagg gtgacgaatc cagcatgacc acgatcgctg acatgcacgg tagtgatggc
    19681 ggttgcgcaa tcagccagag attgccagac gccgatgcgc gccagttgct gacaggtccc
    19741 cgccgctagc gcaatagctc gtccatcaaa gcccggatga gcatgtgact ctggcgcggt
    19801 cgcttcaatc aaatgtaccg gcagcgcccc gtgacttaac cgggaaatag ccagcgccag
    19861 cgtcgcgccc gccatgccgc caccgacgat gattacgctc attgctttct cgcagctgcc
    19921 atcaacgctt cgatttcttc cggctttttc accacgctgg cggtgaggtt ttcgttaccg
    19981 gtttcggtaa tcacaatgtc gtcttcaata cgaatgccga taccgcgata ttgttctggc
    20041 acttctgcat ccggcgcaat atacagccct ggctctacgg tcagtaccat gcccggttcc
    20101 agaatgcgcg agcgatcctg accataaacg ccaacgtcat ggacatctag ccctaaccag
    20161 tggctaaggc catgcataaa gaaaggacga tgggcgttct gagcgatcag ttcatcaaca
    20221 tcacctttca gaatgccgag ttttaccagg ccgctaacca tgatgcgcac cacttcaccg
    20281 gtgacttcct gcatggaagt tcccggacga tacaggcgca agctggtttc gagagactcc
    20341 agcacaatgt cgtagatttc acgctgggcc tgagtgaatt tgccgttgac cgggaaggtg
    20401 cgggtaatat cgccagcgta acctttgtat tcacaacccg cgtcaatcaa caccaggtca
    20461 ccgtcacgca gttcacactc gttttcggtg tagtgcaaaa tgcagccgtt ttcaccgctg
    20521 ccgacaatgg tgttatagga aggatagcgc gcgccgtggc ggttaaattc gtggtgaatt
    20581 tcgccttcca ggtggtactc gaacattccc ggacggcatt tttccatcgc ccgggtatgc
    20641 gccagggcgg tgatttcacc cgcgcggcga agtacggcaa tctcttctgg cgatttgaac
    20701 aggcgcattt catgaacaat gggacgccag tcgatcatcg ttgccggcgc ggtgagattt
    20761 tgtcgcgaac ctttacgcag cttttccagc gcgctgttca cgatttcatc agcataggta
    20821 tattcgccct gggcgtggta aaccacatcc agaccattaa gtaattgata aagttgctga
    20881 ttaatttcgc tgaatgccag tgcgcggtca acgcccagtt tctctggcgc ggcatcctga
    20941 cctaaacgac ggccaaacca gatctccgcc gtcaggtcgc gaacgcggtt aaacagaacg
    21001 ctgtggttat gagtgtcatc gcttttaatc agcaccagca ccgcttccgg ttcgttaaag
    21061 ccggtgaagt accagaagtc actgttctga cgataggggt attcgctgtc ggcgctacgt
    21121 gttacttctg gtgcagcaaa aatcagcgcg gcgctgccgg gttgcatttg ctccaccagg
    21181 gcctgacggc gacgctgaaa ctcttgccgg gatatctcac tcataacact ctccttacgt
    21241 tttttgtttt tagtgtagag tcggtttttg tacttctggc gcggtcggtt gcggatgagt
    21301 aaaggtgtcg tggcataaca gcgcggcaac acgaacgtat tcgatgatct cttcaagcga
    21361 catttcaagc tcttcctgat cttcgtcttc gtcgtaaccc agttgcgcaa tgttacgcag
    21421 atcgtcgata gcttcaccgg tttcgccggt cactttatcc agcttcggtt gcgtaacgcc
    21481 aagaccaagc aggaagtgat tgacccaacc tgccaatgca tcagcccgat cgaaaacgct
    21541 gacatcatcg ccatcaggca gataaagctg aaaaaggaag ccgtcatcct gcagggcatc
    21601 gctggtggca gagtgcattt tacgcagtgc ctgtgccagc tcatgaccga aagccatgcc
    21661 ttcgttcgtc aggtcgtgaa gtagcggtag ccatgagctg tcatcgttac cgccacatat
    21721 catcccgctg attaaaccat gcatctcagc tggggtcaga cccgtccctt gttggttcag
    21781 atactggttc atttcgttgt aaccaggcat ttcgttctgt atagacataa gcattcgtcg
    21841 tcaaagggag gaatattcat gatatgctac cactttgggc cctggtggac cagaaaaggg
    21901 cttgtctctt ctcatcaggg tagctatagt gtcgcccctt cgcagaccat gggtctaaag
    21961 acgaaggcag cgcagtcaat cagcaggaag gtggcatgtc tgcacaaccc gtcgatatcc
    22021 aaatttttgg ccgttcactg cgtgtgaact gcccgcctga ccaaagggat gcgttgaatc
    22081 aggcagcgga cgatctgaac caacggttgc aagatctgaa agaacgcact agagtcacaa
    22141 atactgaaca gttggtcttc attgccgcat tgaatatcag ctatgagtta gcgcaagaaa
    22201 aagcaaagac tcgtgactac gcggcaagta tggaacagcg tattcggatg ctgcagcaga
    22261 ccatagaaca agcgttactt gaacaaggtc gcatcaccga aaaaactaac caaaactttg
    22321 aatgacactt ttcggtttac tgtggtagag taaccgtgaa gacaaaattt ctctgagatg
    22381 ttcgcaagcg ggccagtccc ctgagccgat atttcatacc acaagaatgt ggcgctccgc
    22441 ggttggtgag catgctcggt ccgtccgaga agccttaaaa ctgcgacgac acattcacct
    22501 tgaaccaagg gttcaagggt tacagcctgc ggcggcatct cggagattcc cttcttatct
    22561 ggcaccagcc atgacgcaac taccagaact cccactgaca ttatcccgac aagaaatccg
    22621 caaaatgatt cggcaacgtc gtcgtgcgtt aacgccggaa caacagcagg aaatgggtca
    22681 acaagccgct acccggatga tgacttatcc cccggtggtg atggcacata cggtcgctgt
    22741 attcctctct tttgatggcg aactcgacac ccagccactc atagaacaac tctggcgcgc
    22801 cggtaagcgc gtatatcttc cagttttgca tccctttagt gccggtaatt tgctgttcct
    22861 gaattaccat ccgcaaagcg aactggtgat gaacaggttg aagatccatg agccaaaatt
    22921 ggatgtgcgt gacgtgctac ccctttcccg attagacgtg ctgatcacac cgctggtcgc
    22981 ctttgatgag tacggtcagc gcctgggaat gggcggtggt ttttatgatc ggaccttaca
    23041 aaactggcag cactataaaa cgcaaccggt gggttatgcg catgattgtc agttggtgga
    23101 aaaactcccc gttgaagagt gggatatccc tcttcctgcg gtggttacac cgtcgaaagt
    23161 ctgggagtgg taagggcgat acacccgcat cgccctgatt gacatcgttg attctttgac
    23221 ctaatttagt gagtaagggt aagggaggat tgctcctccc ctgtgactga ctgttaataa
    23281 gctgggaaac ttatgagtaa cagtacaatc agtatgatgg caagtcgcat cataaccctt
    23341 ctccttcaag ccctcgcttc ggtgagggct ttaccgttac agccccatgc tgcccagcta
    23401 tcgtaagctc tctttaaata accacaacgc attgatctac ctttaaatct tttcttcgag
    23461 cgtgctcgaa aaaccccatg caaaacagag ataatttttg ggaaaaagga tctattacgg
    23521 cagtaaacgt gggcgatgaa gtggctatca aaaagttcgg ttcagggcga tgcaccccgc
    23581 atcgccctga ttgacatcgt tgattctttg acctaattta gtgagtaagg gtaagggagg
    23641 atgactcctc ccctgagact gactgttaat aagctccgaa acttatcagt aacagtacaa
    23701 tcagtatgat gacaagtcgc atcataaccc ttctccttta agccctcgct tcggtgaggg
    23761 ctttaccgtt acagccccat gctgtcccgc catcgtaaat ccccattaaa taaacacaac
    23821 gcattgatct gactttgatt tattttctgg agcagactcg caaagtagaa tgcgcaacgc
    23881 ggcaacggtg tggagaaggg ataaaaaaac gggcaagtca gtgacctgcc cgttaatttt
    23941 cagagaaggg gaattagtac agcagacggg cgcgaatggt acccggaata gctttcattg
    24001 cctgcagcgc tttttcggca acgtcttcgt cagcttcaat atcaataacc acataaccca
    24061 tctgggcgga agtttgtaga tattgcgcgg cgatgttgac gccctgctcg gcgaagattt
    24121 tgttcagcgc agttagcacg cccggacggt tttcgtggat gtgcatcaga cgacgcccac
    24181 cgtgcagtgg cagcgagact tccgggaagt tcaccgcaga gagcgttgag ccattgtcag
    24241 aatacttgat caatttaccc gcaacttcca ggccaatatt ctcctgcgct tcctgagtcg
    24301 aaccgccaat gtgtggcgtc agaaggacgt tgtcgaattc acacagcgga gaggtaaatg
    24361 gatcgctatt ggtcgccggt tccgtcggga atacgtcgat tgccgccccc gccagatgtt
    24421 tgctcgccag cgcatcacac agcgccggaa tatccaccac agtaccgcgc gaagcattaa
    24481 tcagcagcga gccgggcttc attagtgaaa tttctttcgc gcccatcata tttttggtgg
    24541 acggattctc tggtacatgc agactcacca catcgctcat attcagcagg tcagaaagat
    24601 gctgtacctg agtggcgttg cccagcggca gtttgttttc aatatcataa aagtaaacat
    24661 acattcccag cgattcagcc agaatgccca attgcgtacc aatatgaccg tagccgatga
    24721 tacccagctt tttgccgcgc gcttcaaaag aacccgccgc cagtttgttc cacacgccac
    24781 ggtgcgcttt agcattggct tccggcacgc cgcgcaatag cagcagcagt tcgccaatca
    24841 ccagctccgc aacagagcgc gtatttgaga acggtgcgtt aaataccggg atcccgcgct
    24901 ttgccgccgc atccagatca acctggtttg ttcctataca gaaacagcca atagcgacca
    24961 gcttttctgc ggcgttgatc acgtcttcag tcagatgggt acgggatcgc aggccgatga
    25021 agtgggcatc gcggatggat tcttttaatt gttcatcatc cagcgcgcct ttgtgaaatt
    25081 cgatgttggt gtaaccagct gcacgaaggc tttccagcgc cttttggtgc acgccttcta
    25141 ccagcagaaa cttaatcttg tctttctcca gcgatacctt tgccatttac ccaatcctgt
    25201 ctttgaaatg ttgtgtgcgg atttgcatcc gcctttcaac atatcaaaaa ataatattgc
    25261 ggcaatatga acgtttgcgt cgcgatgttg aggaaatatc acgcaaaggt atttcttggt
    25321 tgaatatgct ggtttagagg atttatttag agcaatcgac aatagccagg taaaaacgtg
    25381 acacatgtca ccaaatttaa tgaagagaat ttttttaacg ggggaggttc ccccgtcaga
    25441 tcatttcaca atggttttga caccgtcagg tgtgccaatc agcgcaacgt ccgcgccacg
    25501 gttagcaaac aagccaacag tcaccacgcc aggaatcgca tttatggcgt tttccatcgc
    25561 tatcgggtca aggatttcca tgccgtggac gtcgaggatc acgttgccgt tatcggtcac
    25621 tacgccctga cggtattccg gacgaccgcc cagtttcacc agctggcgcg ccactgcact
    25681 acgtgccatc gggataactt ctactggcag cgggaattta cccagaatat caacctgctt
    25741 ggaagcgtct gcaatacaga taaatttttc tgcaaccgaa gcaatgattt tttcacgggt
    25801 cagcgccgcg ccgccgcctt tgatcatttg catgtggccg ttgatttcat ctgcgccatc
    25861 aacgtagatg ccaaggctgt cgacttcgtt gagatcaaaa acgtgaatgc cgaggctttt
    25921 cagtttttca gtggaagcat ctgaactgga aacggcccct tcaatctggc ctttcattgt
    25981 accgagcgcg tcaataaagt gtgcggcggt ggaacctgta cctacaccaa caatggtgcc
    26041 gggctgaaca tactgaagtg ccgcccatcc tactgctttt ttcaattcat cctgcgtcat
    26101 gatcgtttcg cctgtggtat gaaatttcac acgcattata tacaaaaaaa gcgattcaga
    26161 ccccgttggc aagccgcgtg gttaactcat ccataaaata tcgcgcaatg gcaggcatcc
    26221 cctttcgccc cgcaaataag gcatgcaaca atctgggtat gccgctccac ggtgcaaaca
    26281 ggcgcaccag ttcaccggtc gcaagcccct gtttacaggc aaattgaagc aataacgcca
    26341 ccccattcaa cacaaccagg gcgcgaactc gctgagcgaa atgcattagc gcaaatccct
    26401 gatcttttaa gctgcgcgtt taaccacgaa tacaaatgtt acccgccgac ggcttcggta
    26461 tatgcaacct gacacaaaat tgtgtcatag tgcaggaaaa agcatttacc aggagcagac
    26521 aacagcaatg aaacgcccgg actacagaac attacaggca ctggatgcgg tgatacgtga
    26581 acgaggattt gagcgcgcgg cacaaaagct gtgcattaca caatcagccg tctcacagcg
    26641 cattaagcaa ctggaaaata tgttcgggca gccgctgttg gtgcgtaccg taccgccgcg
    26701 cccgacggaa caagggcaaa aactgctggc actgctgcgc caggtggagt tgctggaaga
    26761 agagtggctg ggcgatgaac aaaccggttc gactccgctg ctgctttcac tggcggtcaa
    26821 cgccgacagt ctggcgacgt ggttgcttcc tgcactggct cctgtgttgg ctgattcgcc
    26881 tatccgcctc aacttgcagg tagaagatga aacccgcact caggaacgtc tgcgccgcgg
    26941 cgaagtggtc ggcgcggtga gtattcaaca tcaggcgctg ccgagctgtc ttgtcgataa
    27001 acttggtgcg ctcgactatc tgttcgtcag ctcaaaaccc tttgccgaaa aatatttccc
    27061 taacggcgta acgcgttcgg cattactgaa agcgccagtg gtcgcgtttg accatcttga
    27121 cgatatgcac caggcctttt tgcagcaaaa cttcgatctg cctccaggca gcgtgccctg
    27181 ccatatcgtt aattcttcag aagcgttcgt acaacttgct cgccagggca ccacctgctg
    27241 tatgatcccg cacctgcaaa tcgagaaaga actggccagc ggtgaactga ttgacttaac
    27301 gccggggcta tttcaacgcc ggatgctcta ctggcaccgc tttgctcctg aaagccgcat
    27361 gatgcgtaaa gtcactgatg cgttgctcga ttatggtcac aaagtccttc gtcaggatta
    27421 atccatcaaa taatgcctga tagcacatat caggcgttat cctcacttct ttttgtattc
    27481 cttgaatcac atcacaaaat agacaaatct caggcggcaa aaaacgacgt ctgaatgcat
    27541 tttttttgct ggcgacaaac ccacgtaaaa agctcaccgt aagcgcaaat accctcattt
    27601 tgattgcgtt ttacggagca aataatgtct aacgagcagg agtggcaaca gcttgccaac
    27661 aaggaattga gccgtcggga gaaaactgtc gactcgctgg ttcagcaaac cgcggaaggg
    27721 atcgccatca agccgctgta taccgaagcc gatctcgata atctggaggt gacaggtacc
    27781 cttcctggtt tgccgcccta cgttcgtggc ccgcgtgcca ctatgtatac cgcccaaccg
    27841 tggaccatcc gtcagtatgc tggtttttca acagcaaaag agtccaacgc tttttatcgc
    27901 cgtaacctgg ccgccgggca aaaaggtctt tccgttgcgt ttgaccttgc cacccaccgt
    27961 ggctacgact ccgataaccc acgcgtggcg ggtgacgtcg gcaaagcggg cgtcgctatc
    28021 gacaccgtgg aagatatgaa agtcctgttc gaccagatcc cgctggataa aatgtcggtt
    28081 tcgatgacca tgaatggcgc agtgctacca gtactggcgt tttatatcgt cgccgcggaa
    28141 gagcaaggtg ttacacctga taaactgacc ggcaccattc agaacgatat cctcaaagag
    28201 tacctctgcc gcaacaccta tatttacccg ccaaaaccgt caatgcgcat tatcgccgac
    28261 atcatcgcct ggtgttccgg caacatgccg cgatttaata ccatcagtat cagcggttac
    28321 cacatgggtg aagcgggtgc caactgcgtg cagcaggtag catttacgct cgctgatggg
    28381 attgagtaca tcaaagcagc aatctctgcc ggactgaaaa ttgatgactt cgctcctcgc
    28441 ctgtcgttct tcttcggcat cggcatggat ctgtttatga acgtcgccat gttgcgtgcg
    28501 gcacgttatt tatggagcga agcggtcagt ggatttggcg cacaggaccc gaaatcactg
    28561 gcgctgcgta cccactgcca gacctcaggc tggagcctga ctgaacagga tccgtataac
    28621 aacgttatcc gcaccaccat tgaagcactg gctgcgacgc tgggcggtac tcagtcactg
    28681 cataccaacg cctttgacga agcgcttggt ttgcctaccg atttctcagc acgcattgcc
    28741 cgcaacaccc agatcatcat ccaggaagaa tcagaactct gccgcaccgt cgatccactg
    28801 gccggatcct attacattga gtcgctgacc gatcaaatcg tcaaacaagc cagagccatt
    28861 atccaacaga tcgacgaagc cggtggcatg gcgaaagcga tcgaagcagg tctgccaaaa
    28921 cgaatgatcg aagaggcctc agcgcgcgaa cagtcgctga tcgaccaggg caagcgtgtc
    28981 atcgttggtg tcaacaagta caaactggat cacgaagacg aaaccgatgt acttgagatc
    29041 gacaacgtga tggtgcgtaa cgagcaaatt gcttcgctgg aacgcattcg cgccacccgt
    29101 gatgatgccg ccgtaaccgc cgcgttgaac gccctgactc acgccgcaca gcataacgaa
    29161 aacctgctgg ctgccgctgt taatgccgct cgcgttcgcg ccaccctggg tgaaatttcc
    29221 gatgcgctgg aagccgcttt cgaccgttat ctggtgccaa gccagtgtgt taccggcgtg
    29281 attgcgcaaa gctatcatca atctgagaaa tcagcctccg agttcgatgc cattgttgcg
    29341 caaacggagc agttccttgc cgacaatggt cgtcgcccgc gcattctgat cgccaaaatg
    29401 ggccaggatg gacacgatcg cggcgcgaaa gtgatcgcca gcgcctattc cgatctcggt
    29461 ttcgacgtag atttaagccc gatgttctct acacctgaag agatcgcccg cctggccgta
    29521 gaaaacgacg ttcacgtagt gggcgcatcc tcactggctg ccggtcataa aacgctgatc
    29581 ccggaactgg tcgaagcgct gaaaaaatgg ggacgcgaag atatctgcgt ggtcgcgggt
    29641 ggcgtcattc cgccgcagga ttacgccttc ctgcaagagc gcggcgtggc ggcgatttat
    29701 ggtccaggta cacctatgct cgacagtgtg cgcgacgtac tgaatctgat aagccagcat
    29761 catgattaat gaagccacgc tggcagaaag tattcgccgc ttacgtcagg gtgagcgtgc
    29821 cacactcgcc caggccatga cgctggtgga aagccgtcac ccgcgtcatc aggcactaag
    29881 tacgcagctg cttgatgcca ttatgccgta ctgcggtaac accctgcgac tgggcgttac
    29941 cggcaccccc ggcgcgggga aaagtacctt tcttgaggcc tttggcatgt tgttgattcg
    30001 agagggatta aaggtcgcgg ttattgcggt cgatcccagc agcccggtca ctggcggtag
    30061 cattctcggg gataaaaccc gcatgaatga cctggcgcgt gccgaagcgg cgtttattcg
    30121 cccggtacca tcctccggtc atctgggcgg tgccagtcag cgagcgcggg aattaatgct
    30181 gttatgcgaa gcggcgggtt atgacgtagt gattgtcgaa acggttggcg tcgggcagtc
    30241 ggaaacggaa gtcgcccgca tggtggactg ttttatctcg ttgcaaattg ccggtggcgg
    30301 cgatgatctg cagggcatta aaaaagggct gatggaagtg gctgatctgc tcgttatcaa
    30361 caaagacgat ggcgataacc ataccaatgt cgccattgcc cggcatatgt acgagagtgc
    30421 cctgcatatt ctgcgacgta aatacgacga atggcagcca cgggttctga cttgtagcgc
    30481 actggaaaaa cgtggaatcg atgagatctg gcacgccatc atcgacttca aaaccgcgct
    30541 aactgccagt ggtcgtttac aacaagtgcg gcaacaacaa tcggtggaat ggctgcgtaa
    30601 gcagaccgaa gaagaagtac tgaatcacct gttcgcgaat gaagatttcg atcgctatta
    30661 ccgccagacg cttttagcgg tcaaaaacaa tacgctctca ccgcgcaccg gcctgcggca
    30721 gctcagtgaa tttatccaga cgcaatattt tgattaaagg aatttttatg tcttatcagt
    30781 atgttaacgt tgtcactatc aacaaagtgg cggtcattga gtttaactat ggccgcaaac
    30841 ttaatgcctt aagtaaagtc tttattgatg atcttatgca ggcattaagc gatctcaacc
    30901 ggccggaaat tcgctgtatc attttgcgcg cgccgagtgg atccaaagtc ttctccgcag
    30961 gccacgatat tcacgaactg ccgtctggcg gtcgcgatcc gctctcctat gatgatccat
    31021 tgcgtcaaat cacccgcatg atccaaaaat tcccgaaacc gatcatttcg atggtggaag
    31081 gtagtgtttg gggtggcgca tttgaaatga tcatgagttc cgatctgatt atcgccgcca
    31141 gtacctcaac cttctcaatg acgcctgtaa acctcggcgt cccgtataac ctggtcggca
    31201 ttcacaacct gacccgcgac gcgggcttcc acattgtcaa agaactgatt tttaccgctt
    31261 cgccaatcac cgcccagcgc gcgttggctg tcggcatcct caaccatgtt gtggaagtgg
    31321 aagaactgga agatttcacc ttacaaatgg cgcaccacat ctctgagaaa gcgccgttag
    31381 ccattgctgt tatcaaagaa gagctgcgtg tactgggcga agcgcacacc atgaactccg
    31441 atgaatttga acgtattcag gggatgcgcc gcgcggttta tgacagcgaa gattaccagg
    31501 aagggatgaa cgctttcctc gaaaaacgta aacctaattt cgttggtcat taatccctgc
    31561 gaacgaagga gtaaaaatgg aaactcagtg gacaaggatg accgccgatg aagcggcaga
    31621 aattatccag cataacgaca tggtggcatt tagcggcttt accccagcgg gttcgccgaa
    31681 agccttaccg accgcgattg cccgcagagc taacgaacag catgaggcca aaaaaccgta
    31741 tcaaattcgc ctgctgacgg gggcgtcaat cagcgccgcc gctgacgatg tactttctga
    31801 cgccgatgct gtttcctggc gtgcgccata tcaaacatcg tccggtttac gtaaaaagat
    31861 caatcagggc gcggtgagtt tcgttgacct gcatttgagc gaagtggcgc aaatggtcaa
    31921 ttacggtttc ttcggcgaca ttgatgttgc cgtcatcgaa gcatcggcac tggcaccgga
    31981 tggtcgagtc tggttaacca gcgggatcgg taatgcgccg acatggctgc tgcgggcgaa
    32041 gaaagtgatc attgaactta atcactatca cgatccgcgc gttgcagaac tggcggatat
    32101 tgtgattcct ggcgcgccac cgcggcgcaa tagcgtgtcg atcttccatg caatggatcg
    32161 cgtcggtacc cgctatgtgc aaatcgatcc gaaaaagatt gtcgccgtcg tggaaaccaa
    32221 cttgcccgac gccggtaata tgctggataa gcaaaatccc atgtgccagc agattgccga
    32281 taacgtggtc acgttcttat tgcaggaaat ggcgcatggg cgtattccgc cggaatttct
    32341 gccgctgcaa agtggcgtgg gcaatatcaa taatgcggta atggcgcgtc tgggggaaaa
    32401 cccggaaatt cctccgttta tgatgtattc ggaagtgcta caggaatcgg tggtgcattt
    32461 actggaaacc ggcaaaatca gcggggccag cgcctccagc ctgacaatct cggccgattc
    32521 cctgcgcaag atttacgaca atatggatta ctttgccagc cgcattgtgt tgcgtccgca
    32581 ggagatttcc aataacccgg aaatcatccg tcgtctgggc gtcatcgctc tgaacgtcgg
    32641 cctggagttt gatatttacg ggcatgccaa ctcaacgcac gtagccgggg tcgatctgat
    32701 gaacggcatc ggcggcagcg gtgattttga acgcaacgcg tatctgtcga tctttatggc
    32761 tccgtcgatt gctaaagaag gcaagatctc aaccgtcgtg ccaatgtgca gccatgttga
    32821 tcacagcgaa cacagcgtca aagtgatcat caccgaacaa gggatcgccg atctgcgcgg
    32881 tctttccccg cttcaacgcg cccgcactat cattgataat tgtgcacatc ctatgtatcg
    32941 ggattatctg catcgctatc tggaaaatgc gcctggcgga catattcacc acgatcttag
    33001 ccacgtcttc gacttacacc gtaatttaat tgcaaccggc tcgatgctgg gttaatgact
    33061 cgtcccgtca cgatcttcag caatatgctg aagcatcgtg gcggtataac gatgatttct
    33121 gattgaataa agatattcct gcatatacat cggcctgtgc ggcgcatcaa aatatttcag
    33181 cgttgccgga ttcaccagtc gccaggcaaa atgcgggatc accgtcagaa aatgtccgcg
    33241 ctccacggcg ctgattttgg ccataaaact gtagggacga taaataatgg ttggattgat
    33301 cccacaaggt cgcatattcg catcaatcat tgcttcgaag ttggcccggt tctgaaagcg
    33361 catttgtagc cagggcagct cctgaagcag ctcttgctct tgacgctctt cataacggcg
    33421 agaaacgaga aagcctaatc gcagcggtgg tagttcactg atagtcaggt tttccagttc
    33481 ctgaactcgt gcagatacat gctgtgggga gataataaaa tctaactggc ggtcaaaaag
    33541 attatcgata acgccgtttt cgctgaactc aactggctgg gcggtcacgc cttcatactt
    33601 atctccgaga ctaatcaact gatcgaaaat aattgtcgga taagtattat ctatgccaat
    33661 cacaatttct cgtgaacgac gtcctgagtt atggatttca ttatcaatcg cagaaagccg
    33721 ttgataaacc gggaacagtt tttgatacag ttcctgtccg gctttattga ggctgatatt
    33781 attatctttg cgggtaaata gcgtatagcc aatttgttct tccagcgcgg caatgctttt
    33841 accaaatggc gaagccgtca tatggatttt ttctgccgcc cgggcaatat tattggtttg
    33901 cgctaataaa atgaaattgc gcatcttttt cgaaataaaa atgtccatcc ccctcccccg
    33961 catccttgtc cgcttaaccg tttcagtcag cctatccttg atgaaaccgc gagcaaagat
    34021 aggtgattac gtcatggttt tacagaaaat tacagaaaaa ggaggcaata tcgggtaaag
    34081 gcattagccc gacgaatacg tcgggctaca agtattattg tgctgcaggt gttttagcgg
    34141 gttgttgatc cacaggttct aactggaaga ccacatcgac ctgatcatca aactgaatag
    34201 cggcctgctc gtaagtttcc tgggcggaca ccggcgcggc atcggctttc atcatccgca
    34261 ccattgggct gggctgatag ttggaaacat ggtagcgcac gctatatacc ggccccagtt
    34321 tacgatgaaa gccgttcgcc agttcctgcg cctgatgaat cgcgttatca atcgctgcct
    34381 tacgcgcttt gtctttatag gcatccggct gcgccacgcc cagcgacaca gaacgaattt
    34441 cgttaagacc cgccttcagc gcgccatcca gcaaggaatt cagtttgtct aactgacgga
    34501 gcgtgacttc caccgttctc acagcgcggt agcctttcag gatactttta ccatcctgat
    34561 aatcataatc tggctgggtg cgtaagttcg ctgagctgat atcttttttc gcgatctgat
    34621 tgagttcaag gaaggaaatg tattgtgcga cgcgctcatc tgcctgtttc ttggcagtag
    34681 cggcatcctt cgcggccacg ttaacttcaa tcgcaagagt ggcaatgtct ggcaccgcat
    34741 ccacgcttgc cgtaccggag gtgacaatat gcggtccatc cggcaattcg ttagcctgcg
    34801 ctgccatccc gctaataccc attaatgccg ccagggcgat aactttgaac ttcacgttag
    34861 tctctccgtg ttaattgact tgcccaaaat tcaggacctc tggaggcaag cttagcgcct
    34921 ctgttttatt tttccatcag atagcgccta actgaacaag gcttgtgcat gagcaatacc
    34981 gtctctcgcc agctgcaagg ctataaacca catgacacat cccactacca gattgataat
    35041 gcgctgtgat tttgccgtgc gcaggcgcgg tgccagccag gctgcgagaa tagccagacc
    35101 aaagaaccac aggaaagagg cgctaattgt cccgagcgca aaccaacgtt ttggttcgac
    35161 gtcaagctgc ccgccaaggc tgcccagtac aacaaaagta tccaggtaaa catgcggatt
    35221 cagccaggtc actgccaaca tggtggcgat aattttccat ctgccttgct tcaggacttc
    35281 ggcactggct aactcaatat tactgctcat tgcggtttta aaagcgccaa aaccatacca
    35341 cagcaagaag gctacgccgc cccaggtgac cagcgccagc aaccacggcg actgcatcaa
    35401 taacgcgctg ccaccaaaaa tcccggcgca aatcaggacc aaatcgctga tagcacaaag
    35461 taaggcaatc ataatgtggt actgacgacg aatgccctga ttcatcacaa aagcattttg
    35521 tggaccgagc ggtaggatca tagctgcgcc aagcgcaaga ccttgaaagt aataagaaaa
    35581 cacgttggat attccgaatt aagtatctga tgcagagact atatcgcggg attgttatta
    35641 gcggaaattg ataatattaa ttggcaatca gaaaaactaa taagagagag gccagagagt
    35701 attatctggc ctcagcgttg attacgcagc tttgtcttct ttcacccgct taaagttcac
    35761 atccatttgc gggtacggga agctgatacc ggcggcatca aattcacgtt taatacgctc
    35821 cagcacatcc cagtacacgt tttgcagatc gccgctgttg ctccagacgc ggaccacgaa
    35881 attaatcgac gatgcaccaa gttcgttcag gcgcacagtc atttcgcgat ctttcaaaat
    35941 gcgatcttca gactggataa tattggtcag gatctgctta acctgatcga tatcggaatc
    36001 atacgccacg ccaataataa attcgttacg gcgaactggc tcgcgggaga agttaataat
    36061 atttccggca ataattttac cgttcggaat aacgataatt ttaccgtctg cagtacgcat
    36121 ggtggtggag aaaatctgca cactcagcac agtaccggct acgccgccga ggtcaacata
    36181 ttctccggca cggaacgggc ggaacatgac aagtaacacg ccagcggcca ggttagacag
    36241 tgacccctgc aaagccagac caacagctaa gcctgcggca ccgagtacag caatgacgga
    36301 cgcggtttgt acacccacgc gtcccagtgc agcgattaga gtaaaggcga taataccgta
    36361 acggactaat gcagaaagaa aatcagcaac agtggcatcg attttacggg agatcatcag
    36421 gcgattcacc gcgttggaaa tcatccgcgc gataatcaaa ccaacgatga tgatcgcgag
    36481 tgccgccacg atgtttactg cataacttag cagcagcgcc tggttagcta ccagccagct
    36541 tcccgcgccg tttatgctat cgacaacatt caaatcttcc attcaatatt ccttttcaac
    36601 tgactcaaaa tggagaaata cactccgccg ccttatgacg ggcagtctga caagggtaaa
    36661 caataaagca taattttgcc aaatagatca cagatttctc atctgaatca ccttgctttt
    36721 ggcgaaaaaa tccccgcaga gcggggctca gacagatatc aatgtgcgct ttgtcatgcc
    36781 ggatgcggcg tgaacgcctt atccggccta caaaaacctg caaattcaat atattgcagg
    36841 atacgtgtag gcctgataag cgtagcgcat caggcaattt tgcttttggc gaaaaaaaga
    36901 cccgcagagc gggccttgag ataagcagaa aggaatatct tacagaacgt cgatcgcgtt
    36961 cagttcctgg aatgcttttt ccagacgagc aatcatcgaa gtctgaccgg cacgcagcca
    37021 tacgcgcgga tcgtagtatt tcttgttcgg ctgatcttcg cctttcgggt tacccagctg
    37081 accctgcaga taagcttcgt tcgctttgta gtagttcaga acgccttccc aggttgccca
    37141 ttgggtatcg gtatcgatgt tcatttttac tacgccgtag cttacggagt ctttgatttc
    37201 ctgagcagta gaaccggaac caccgtggaa tacgaagttc aggctgttgt gcggcaggtt
    37261 gtgtttcttg gaaacatatt cctgagaatc acgcaggatg gtcggagtca gaaccacgtt
    37321 acccggcttg taaacaccgt gtacgttacc gaaggacgct gcgatggtga aacgcgggct
    37381 gattttgctc agttcggtgt atgcgtaatc aacgtcttcc ggctgggtgt acagtgcaga
    37441 agcgtccatg tggctgttgt ccacgccgtc ttcttcacca ccggtgcaac ccagttcgat
    37501 ttccagagtc atgccgattt tggacatacg ctccaggtat ttagagcaga tttcgatgtt
    37561 ctcttgcaga gattcttcag acaggtcgat catgtgagaa gagaacagcg gcttgccggt
    37621 agctgcgaag tgtttttcac ccgcgtccag cagaccgtcg atccacggca gcagtttctt
    37681 cgcgcagtgg tcagtgtgca ggataaccgg aacaccataa tgttcagcca tctggtgaac
    37741 gtgatgcgca ccagagatcg cgcccaggat agcagcaccc tgcggaacgt cagatttcac
    37801 gcctttacca gcgataaagg aagcaccacc gttggagaac tgaacgataa ccggcgcttt
    37861 aactttagca gcagtttcca gtacggcgtt gatggagtca gtaccgacgc agtttactgc
    37921 tggcagtgcg aagttgtttt cttttgctac ctggaaaact ttctgtacgt catcaccagt
    37981 gattacgcca ggttttacga aatcaaaaat cttagacatg tctcttgtcc tgtatcgtcg
    38041 ggccttatac tcatcatact tcaagttgca tgtgctgcgt ctgcgttcgc tcaccccagt
    38101 cacttactta tgtaagctcc tggggattca ctctcttgtc gccttcctgc aactcgaatt
    38161 atttagagta tgaaaaaatg cgtgctctaa aagcgcgctg aaacaagggc aggtttccct
    38221 gccctgtgat tttttacttc ttagcgcgct cttcgagcat cgctactgca ggcagtactt
    38281 taccttccac gaattcgagg aatgcgccgc cgccagtgga gatgtaggag attttgtcag
    38341 caatgccgaa caggtcaatt gctgccagag tgtcgccgcc gccagcgatg gagaacgctt
    38401 cgctgtctgc gatagcgtta gccacgattt cagtaccttt gcggaagttc gggaattcga
    38461 acacgccaac cggaccgttc cacagaatgg ttttcgcatt cttcaggatt tcagccagtt
    38521 cctgagcgga agcatcaccg atatccagga tctgctcgtc agctttcaca tcgttaacag
    38581 atttcagggt agccggtgca gtttcagaga actcggttgc tacgcgaaca tcagacggaa
    38641 ccgggatgtt gcaggtggtc agcagacgtt tagcttcgtc aaccaggtca gcttcgtaca
    38701 gggatttacc cacatcgtgg ccttgtgccg cgataaaggt gttagcgata ccaccaccaa
    38761 caatcagctg gtcagcgatt ttagacaggg agtccagaac ggtcagtttg gtagatactt
    38821 tagaaccacc aacgatagcc accatcgggc gagcaggttc tttcagtgct ttacccagcg
    38881 cgtccagttc agctgccagc agcgggcctg cgcacgcaac gtcagcgaat ttaccgatac
    38941 cgtgagtaga agcctgcgcg cggtgagcag taccgaatgc gtccattacg aacacgtcac
    39001 acagtgcagc gtattttttg gacagggttt cgtcgtcttt cttctcgcct ttgttgaagc
    39061 gaacgttttc cagaacaacc agttcacctt cagcaacgtc aacgccgtcg aggtaatctt
    39121 taaccagacg aaccgggtta gacagtttgt ctttcaggta gttaacaacc ggcagcagag
    39181 agaattcttc gttgtactcg ccttcggtag gacgacccag gtgggaagtt accatcactt
    39241 ttgcgccttg tttcagggcc agttcgatgg tcggcagaga agcacggata cgcgcgtcgc
    39301 tggttacttt cccgtctttt actggtacgt tcagatccgc acggataaat acacgtttcc
    39361 cagcaagatc cagatcggtc atcttaatta cagacatggt gaatcctctc gttgattcta
    39421 aaagttttgc agacgctgct tgcgtcttac ctgaaagcaa cagtagccat agctaacgtc
    39481 gtgtcgagca ttcggttagc aaagccccat tcgttatcgc accagaccaa cgttttgatc
    39541 aggtgtgcgc cactgacccg ggtttgggtg ccatcgacaa tggcactgtg cggatcgtgg
    39601 ttaaaatcta cagagaccaa cggcaattcc gtatagtcaa ctataccatg aaatgcacct
    39661 tgtgctgctt tttgcagcaa caggttgact tcattggctt ttacaggttt cttcaccgtc
    39721 acgcttaaat cgattgccgt cacatttatg gttggcacac gtaccgcaat cgcttcaaag
    39781 cgatcgttaa attgcggaaa aaatcgtgtg ataccggcgg ccagtttagt atcgaccgga
    39841 atgatcgact ggctggctgc ccgggtgcga cgcaggtcag gatggtatgc atcaataacc
    39901 tgttgatcgt gcatggcgga gtgaattgtg gtcacagtgc cggactcaat accgtacgca
    39961 tcatctaaca atttgatgac gggaattatg caattcgtgg tacaggaagc gttagaaacg
    40021 atgcggtgtt ccgcacgaag ttgatcctga ttgacgccgt aaacaacggt cgcgtcgaga
    40081 tcgttactgc caggatgtga aaagagcact tttttggccc cggcggcaat atgcgcttcg
    40141 ccatgctcgc gggagccata tacgccggtg cagtcgagga ctacatcaac gccaagttca
    40201 cgccagggga gcgattgcag tgaacgttca tgcaatacgc ggatggcgtc atcaccaaca
    40261 aaaagttgat cgcgttcctg tcgtacttcc catgcaaaac ggccatggct ggtgtcatat
    40321 ttcaacaaat gcgccatgcc cgcagcatcc gccagttcgt tgattgccac cacggtaatt
    40381 tccgcccggc gtccggattc atacaaagca cgaaccacat tacgcccgat gcgaccgaag
    40441 ccatttatcg ctacgcgtac ggtcatagat ctcctgcaag gttttccctg agcaaatttg
    40501 ccagacagag taatccagca aatcgtccgg ggaaacctta cctgtcgcaa actgcgactg
    40561 attggttaat tgtcgaacat ttaatcgact gaaacgcttc agctaggata agcgaaacgt
    40621 ggaataaaag gaatgattgt ccagtcaaag aaagcaatta tctgacttac gtcacgtttt
    40681 cagccccgcc cctgtggaat ttattccact ttgcagaatc acgaataagc gtagcaaaat
    40741 cttttcgttg tgccgtcaca aaccctgact tatatcagaa tatgactgat gcagcgtcga
    40801 tattatccgc aatacgtccg agtttcggag tactccaatg atgacattgc cctacccata
    40861 ttcttcctcc gcacgctttt acgcactgcg cctcctcccc gggcaggaag ttttttccca
    40921 gctacacgct tttgcacagc agcatcaact tcatgccgcc tggattgcag gctgtaccgg
    40981 tagcctgact gacgtcgcct tgcgctatgc cgggcaagaa ggcaccacgc tcctgaacgg
    41041 tacattcgaa gtgatctcac taaacggcac gctggaacag agtggtgagc atcttcatct
    41101 ctgcgtttcc gatccacacg gcacgatgct tggcggtcat atgatgcccg gctgtaccgt
    41161 gcggaccacg cttgaactgg tgatcggtag ccttgaggaa ctggcgttta gccgccaacc
    41221 ttgcgcgctt tctggttacg acgagttgca tatttccccc gttaaataac tactttcaaa
    41281 gaggttttct tatggcgcgt agccactttt ccagtcaggc actggtgttg atcgttatat
    41341 ctatcgccat caatatgatc ggcgggcaac tggccagcat ggtcaaatta cctatatttc
    41401 tcgactccat cggcacactt attagcgcgg tactgcttgg tccggtgatc ggaatgctga
    41461 ccggcttact gaccaattta ctctggggat tgctgaccaa cccgatcgcc gccgcatttg
    41521 cacccgtcgc gatggtcatc ggcctggtcg ccggttgcct ggcgcgagcg ggttggtttc
    41581 gcaccctgcc aaaagtcgtt gtcagcggcg tgattattac gcttgcggta acggtcgtcg
    41641 ctgtaccgct gcgtactgcg ctgttcggcg gtgtcaccgg tagcggagcc gatttgttcg
    41701 ttgcctggat gcactcgatg gggcaaaacc tggtggagtc ggtggcgatt acggtgatag
    41761 gcgcgaacct ggtcgataaa attcttacag cggtgattgt ctggctttta ctgcgccagc
    41821 tgccgattcg caccacgcgc cattttccgg caatggctgc cgtgcgctaa atgcatccat
    41881 ttacctcatt aacactgtgg gcattggcgg cctgcaccac gcttatcctg cccgcgcaga
    41941 ccattttgcc aatctatagc gcggcgacct ttttctgcct tattgcgcta aaggccacgc
    42001 ggcggcgggc aaaatatgtc gtctggctga tgttctcgct gggagccggg ctgtggctgg
    42061 tacacggtgg ctggctacca gaatggctaa gcggcacgcc acgctcgcca gaacggtggt
    42121 cgcatgctat tacgctctgg ttgcggattc tggcgattgt ttcaacctca cagttgtgga
    42181 tgcagtacgt ccccgtgcaa tgttttattc gcgctctgtt tgcttctcgc ctgccgccag
    42241 gcgtcgctta tctgtttgcc gggccgttat tggtcgttga gcagttaaaa cggcaattag
    42301 cgattattca tgaagcgcag cgtgcccgcg gcgtgccgct ggatgagggc tggtatcagc
    42361 gtttacgtgc gatgcccgcg ttaattattc cgctaacaca caatgcgctt aacgatctgg
    42421 ctgtccgtgg tgcggcgctg gatatgcggg catttcggat ccacaaccga cgaacaacgt
    42481 tgtgggcacc agccgatagc accctacaac gcgtagcgcg ttacaccatg atcttgctga
    42541 tgctgacaga attcggagcg tggatatggt tacgttagaa cagttccgtt attgcccgac
    42601 acactcaacg catcctccgt tctgttatga ctttcactat gtcaaaccgg ggatggtcgc
    42661 catctttggt gacaacggca gtggcaaaag tacgctggca cagctgatgg cgggctggta
    42721 tccggacttt ctgccaggag agataacagg cacggggacg ctcctcggta cgcccattgg
    42781 gcatctcccg cttaatgaac aatccgccac catccagctc gtccagcaat cgccctattt
    42841 gcagctctcc ggctgtacct ttagcgtgga agaagaagtt gcctttgggc cagaaaatct
    42901 gtgtcttgct gaagcagaga ttatggcgcg gattgatgcc gccctgactc tgaccgagtg
    42961 ccagccgttg cgccatcgtc acccggcaac actctccggt ggagagacac agcgcgtggt
    43021 catcgcctgc gccatcgcga tgcagccaaa gctcttaatt cttgatgaag cctttagccg
    43081 cctgactccg caggccagcg aaatgctgtt gcagcgctta caacactggg cgtttgaacg
    43141 tggttcgctg attattcttt ttgaacgtca tcgcacacct ttcctgaact actgccagca
    43201 agcgtggcaa ttgcaaaacg gagcgctcca gccactatgt taacgttaaa taagatatct
    43261 tatcgctggc ctggcgcggc aacggattgt ctttgcgaca tttctctgca actcaaacaa
    43321 ggtgaatggt tggcgctgac cggcgacaat ggcgcaggga aatcgacgct gttacgagta
    43381 atggcaggtc ttcttacgcc cacagccggt acggttatgc tgcaacaaca ggcgatgaaa
    43441 aacctgaaaa accgccagcg cgcggcaaag attggcgtac tgtttcagga agcggaaaac
    43501 caactttttc acagcaccgt cgctgacgag atcgcatttg gtttgaaact gcaaaaatgc
    43561 ccggcggatg aaatcactca acgtacccat gctgccctgc aatgttgtca gttagcagac
    43621 actgccaacg cgcacccgtt ggatctgcat agtgcgcagc gacggatggt cgccgtcgcc
    43681 tgcctggaag cactctctcc gccactattg ctgctggacg agccgagtcg ggattttgac
    43741 gaaaattggt tgagcgtgtt tgaaagctgg ctggagaagt gccgccagcg aggcacgagc
    43801 gtcgtagcaa tcagtcatga cgccgcattt acccggcgtc atttctctcg tgtggtgcga
    43861 ctggaagatg gtctaatcag gaacgttaat ccaccagacg atattcaccc gtagcggtca
    43921 tcattaaggt caaatttgca ggcagactct cttccagcac ccggcgaaca ttcggcccgt
    43981 cggtacggtc ataaaaagct tctgcgtctg ccagcgatac ccctcccgcc agcttgcgcc
    44041 ctaccagtcg ttcccgcaac gcagtagctg gcgcgttgat aaagatcgag aaatcacaaa
    44101 attgcgcaag ctggcaccac ttctcgtcgt ccagcaacaa ccagtttcct tcgacgatga
    44161 cgagtggtgc ggtaacgtgc aacgcatctt caacaggatc atgcttttgt cgatcgtact
    44221 gcggccacgt acaatctcct tccacgacct ggcgcagatt ttccgccagt ttcacaacgt
    44281 caaatgtctc tggtgcgcct ttgaaggggc gcaattgatg cgcgtccagc cagctattgt
    44341 aatggtgaaa accatccatc gggagcgtct gaatagcggg cagttccggg tcttgttgcg
    44401 cgagatattc ccagaaggta gttaaggtag atttacccgt ccccggcgga gcgcaaagaa
    44461 aaaccaccgt acgtcgctgc gaacttaccg cctgtaaggc cgccagcata cgcagtagcg
    44521 gtttatgaac attctcaatt tcatcatcag agtactgagc ctgtaccttt agtccattca
    44581 ccgtcagttc gatattcacg gcgttaattc ctttaaagtt gtcgttactg ccagcgtcag
    44641 cgccgttttg accattccgc taaaacgcgc ctctgaccag acggcgaaat cggcgaactt
    44701 catcgctttc aacgcgtcat agagcgtcgc attgcaggtt atgctattga cgttgctgat
    44761 aaaatcccag gtcatgtcat cggcaaatcc gggcgtttca tcctgttcgt tcaggtaatg
    44821 ccagaactgg gaaaaatgcg tgatatcggc gtacagccat ttatccattt tccccagcgc
    44881 ataaatcaaa cgcagtgcaa catcaatatc gtcaagcggg ccgctttggg cgagtaacgg
    44941 cttcactgca tattcgacga tctcttcatc gttatcgaca aacagcgacg gcagaaactg
    45001 gcgtatcccc tggagcaaaa tagaatgcgc agttttcata aatgaaaata aattgtcctg
    45061 tgcatccagt tgctcaagca catcatcttc tgtcagcgtc gccattggtc ttccgataga
    45121 tcaccatcaa tgcagggagt ctattatatt acacgtttgg tccgcgccgc cgatcagtaa
    45181 tgtctgcgtc cgcaccccat tcgccgtctg ttggataccg ttcaccaact cgccgcccgt
    45241 cacgcccgta gcgctaaaga ggatatcgtt ccccctcacc agttcatcga gcgagtacac
    45301 acggttaacg tcaacgccca ttgccttaca acgcttgcgc tcctgctctg caatctgccg
    45361 attttccgtg taatcccctt tagcctgaca aaagtcaatc agctcggcct gcatatcccc
    45421 acctaatgct ttaacggcac aggcagaaat cacgccttct ggcgcaccgc cgatggtgta
    45481 catcacgtcg taaggattat cctgccagca ggtcagcacg ctggcggcga catcgccatc
    45541 cggcagagcg aaaaccttca cgcccagctg tgttgcttct tcaatcgcgg cactcaggcg
    45601 cggtttatcc agcgtaacca tgcgcagctt gtccagcggt ttgcctaacg cccgcgccac
    45661 gttgcgcaag ttgtccgcca gaggcaaaga cagatcaatc gccccggcag ccagtcgatt
    45721 aacaaccagc tttttcatat acatatcggg cgcatgtaac aggctatctc gaggggcgaa
    45781 agccatgacc gccagcacat tgctctgccc catcgctacc atccgcgtgc cttcaatcgg
    45841 gtcaaccgcg atatcgactt ctggcccatc gcctttgccc acctcttcgc caatccacag
    45901 catcggcgca tggtcaattt ctccttcgcc gataaccact cgtccacgaa aagcgacgtc
    45961 gtttaatgcc tggcgcatcg cggtgaccgc caggccatca attttatttt tgtcgccaca
    46021 tccggtttgc ggccaggcag ccaacgctgc ctgttccgta acgcgaaata atggccacgc
    46081 cagggacatc attgcgcggc ctccccaata tcaacgccaa attgcgccag cagatatttc
    46141 tcggcctgct cattccagat gccgtgcgtt tcctcaacca gccgcgccag ctctttaaac
    46201 agcggatcgg ttttgccttt ttcggcaaaa tcggcaatgg cagtgagcgg catggtcacg
    46261 ccgttataaa tgagtttttt accgccaggg atatccggca gattgagcac ggtatctggc
    46321 accgcatcca gcccaccgat atgcgtgacc ataaaggacg gctgcaactg ccccgtggcg
    46381 cttaacgcaa tcgcctcttt catgtcgtcc gttgaaccgc cggatgtacc gacgacgtgc
    46441 gtgctgttgt aatggacgtt gtagaaatta aacggcactt tgaagttttt atccgtcggc
    46501 ccggcaaaga agttcagaca gccatcttcc gccagtaatt cgtcagccat ctcaacgaca
    46561 gcaggcaccg ccgcataaac aaaaatgtca tcgaacccga catctcctgt cagcgcccgc
    46621 agcgtctgga ccggatcgct catccctttg gtattcacat acaccagctc aatgccttta
    46681 ctggccgcca gatccaccgg cagcagcttc tgcacctgcg ccaggcgttt gtcgtcgata
    46741 tcgaccacca ccacccgtga cggttgtatg ccaccgttaa tggcgtaatc gatagcgcca
    46801 atgcccatcg gacccgcaca cgccagcagt gcaatattgc cgccaggttt gacgcccatg
    46861 cgatgctcat aaacatattg cgtggtgtga taattggcat gataagcacc aataatgcag
    46921 cacataggct ctgccagcga cgccgcagca aaataagagc cgtgatacgg taatacgcag
    46981 cccaaattaa tggcgatttc gggaataatc atataggtgg cgttaccgcc aaaatattcg
    47041 tagctgtagc ctgctgaata tccgcttggt aaccccatcg ccggttgcaa tacaaaacgc
    47101 tggccttttt tatatttgcc agtgagattt ttacccactt cgacaataac cccggcacat
    47161 tcatgcccgg taatgaccgg atgattttct aaatcgtcgg gtacgcgttt atgttcacta
    47221 ccgagtaacg ccgctttcca ggtcgataaa cagacgctgt cagaaattac actctctaac
    47281 agttcattat cggtaatttc tggcagttca aattcgcgca gacggacatc ccgcttgcca
    47341 taaatagcag caactttggt tttcattttt acctctgtaa tcagtgttta tgttcggcgg
    47401 ttaattgatt aaataaagtg tcgagttttg gatcgccaat atagttatta atcaatatca
    47461 gcggtttatc cgtaacacgt ttcacgcgcc cttccagact ggcatgagta acgacgatat
    47521 cggcatccgc aggcacgttt tctatcgcgt aatgttttac ttctattgcc agccccgctt
    47581 tttccaggcg tttacggaag gtggtcgcgc ccatcgcact ggagcccatc cccgcatcgc
    47641 aaacaaaggc gatacgctta accctgctta acgagaatgc accctcttgt ttcatcgcct
    47701 taaccgcatt ggctgactga gcaaactcat cttcgctctc cgtttccacc gttttttcca
    47761 tcttcagtat cagcgaagta atagcaaagg acaccagggt acctaccgta acaccggcaa
    47821 ttgtcgccag gaacgagcct ttcggcgtca gtgccaggta agcaaagata gaccccggac
    47881 ttgggccagc caccagacca ccgtccagta agttaaacat ccaggtacca gacataccgc
    47941 ccgcaatcat ggcaataata gtcagcggct tcatcagcac atatgggaaa tacagttcgt
    48001 ggatcccacc gaggaagtga ataatcatcg ccccgggcgc agaacgttta ctcatccctt
    48061 taccaaacaa ggtaaacgcc agcagcagcc ccaggcccgg acctgggtta gaggccacca
    48121 taaagaagat ggatttaccg ttaaccgaag cctgttgcat tcccagcgga taatagacgc
    48181 cctgatcgat cgcattatta aggaaaagca ctttcgccgg ttcattgatg actgacagca
    48241 gaggcagata acccgcatgt accagcgcct cgatacactc tttgacgaaa gtattggcaa
    48301 ttaacaccgc cgggccgatc acttcaaaac ccagcagaca aaggagcatc cccgcgatac
    48361 ctaatgagaa gttattgata accatctcaa aaccggcagg tatgcgtttt tccagtgcct
    48421 tatcgacata ttttatgacc aacccaccga gcggccccat gatcattgag ccaaggaaca
    48481 tcgggatctc tgcgccaacg atcacaccaa tagtacctat tccgcccatg accgccccgc
    48541 gtttaccgcc gaccagatga ccacctgtag aaccaatcat cacgggcaat aaataggtaa
    48601 tcatcgggcc gacaattttg gcgaaatgtt cgttaggcag ccaaccggtg ggaataaata
    48661 acgcagtaat aaaaccccag gcaataaaag caccaatatt ggggatgacc attgcagtca
    48721 aaaagccccc aaaagcctgg acctttgcac gagcagactt gttttccata atattatcct
    48781 gtagaggaga gagtaattat ccgcggctga taatgtccgc taattgtttt tctgatgatg
    48841 ctgttaagag ttgttcgagt atttcttctt cgcacagtaa ttcacttaac gcctgaatag
    48901 cgccaatgtg cgaatcggca tcggcagcag agagtccgat gagtaattta attggttcgt
    48961 cattccccgg aaaataaaca ccttgttcaa gtaatgtcaa agacatcccg gttttaagcg
    49021 ccccacattc cggtcgcgca tgaggcattg ccacgcctgg tgcgagaata taataagggc
    49081 cattgttaat ggtggaatct ttaattgcct gaatgtaatt ctcgctgata tagtttttat
    49141 ccagcaatga taccatcgag aaatcgatag cttcctgcca atcttttgct gaatgtataa
    49201 ctgagattga tgattctgga aaaataatca ctaagccgca taaattatcc ttattttatt
    49261 tttagggtac cgtccggcgg taaaaataaa atactcgtgc ggtttaatga aagcaattga
    49321 gcagggaaac cgatgttttg aaaacagtga attattaatt tcttatataa cattgagtta
    49381 tagatataac aacaaatgtc aatacgcata tcgtgatgca tattacataa ttgatattta
    49441 ttgcatataa atatttgtga tctacaacac gctttatcta ttgcttgtcc gcaaacggac
    49501 atatcaaggt aataaaaaag gtcgccgaag cgaccttttt acccgaaatg ctaattacag
    49561 cagttctttt gctttcgcaa caacgttatc aacagtgaag ccgaactctt caaacagcag
    49621 ctctgccgga gcagattcac cgaaggtggt cataccgacg atagcaccgt tcaggccaac
    49681 atacttgtac cagtagtcag caatacccgc ttctacagca acgcgtgcag taaccgcttt
    49741 cggcagtacg gattcacggt aagcagcatc ctgcttgtca aatgcgtcgg tagacggcat
    49801 ggacaccacg cgcgctttca cgccttcggc agtcagtttt tcgtaggcag caacagccag
    49861 ttcaacttct gaaccggtag cgatgaaaat cagttccggc tgaccggcgc agtctttcag
    49921 cacataacca ccgcgcgcga tgtttgccag ttgctcttca gttcgttcct gctgcgccag
    49981 gttctgacgg gagaggatca gtgcggtcgg gccgtcctga cgctcaacac cgtatttcca
    50041 cgcgaccgcg gattcaacct ggtcacacgg acgccatgta gacatgttcg gggttacgcg
    50101 cagagaagcg acctgctcta ccggctggtg agtcgggcca tcttcgccca gaccgatgga
    50161 gtcgtgggtg taaaccatca cctgacgctg tttcatcagc gcagccatac gtacggcgtt
    50221 acgtgcgtat tccacgaaca tcaggaaggt ggaggtgtac ggcaggaaac caccgtgcag
    50281 ggagataccg ttagcaatcg cggtcatacc gaactcgcga acaccgtagt ggatgtagtt
    50341 acccgcagca tcttcgttga ttgctttaga accagaccac agggtcaggt tagacggtgc
    50401 caggtcagca gaaccgccga ggaattccgg caacagcgga ccgaaagctt cgatagcatt
    50461 ctgagacgct ttacggctgg cgattttcgc cgggttagcc tgcagtttag caatgaactc
    50521 ttttgctttc gcgtcgaagt cagacggcat ttcgcctttc atacggcggg taaattcagc
    50581 ggcttcctgc ggataagctt tcgcgtaagc agcgaatttc tcgttccatg cggattcttt
    50641 cgcctggcct gcttctttcg catcccactg agcatagatt tcagacggga tttcgaacgg
    50701 tgcatatttc cagcccagct gttcgcgggt cagggcaatt tcagcgtcgc ccagcggcgc
    50761 accgtgggag tcgtgagtac cggctttgtt cggggaaccg aaaccgatga tggttttgca
    50821 catcagcagg gacggtttgt cagtcactgc gcgcgcttct tctactgcgc gtttgatgga
    50881 tgccgcgtca tgaccgtcga tgtcgcgaat aacgtgccag ccgtaagctt cgaaacgcat
    50941 tgcggtgtcg tcggtgaacc agccttcaac gtgaccatca atagagatac cgttgtcatc
    51001 gtagaacgca atcagtttac ccagcttcag cgtacccgcc agagagcaaa cttcgtggga
    51061 gatgccttcc atcatgcagc cgtcgcccat gaaggcatag gtgtagtggt cgacaatgtc
    51121 gtggcccgga cggttaaact gcgccgccag cgttttttct gcaatcgcca taccgactgc
    51181 gttggcaata ccctgaccca gcggaccggt ggtggtttcc acaccagcgg tgtaacccac
    51241 ttccgggtga cccggagttt tagagtgcag ctgacggaag tttttcagtt cttccatcgg
    51301 cagatcgtaa ccggtgaggt gcagcaggct gtagatcagc atggagccgt ggccgttgga
    51361 cagcacgaag cggtcacggt cagcccagga cggattctgc gggttgtgtt tcaggaaatc
    51421 acgccacagg acttcggcaa tgtcagccat acccataggg gcacccgggt gaccggattt
    51481 ggctttctgt actgcgtcca tgctcagcgc acgaatagca ttggcaagct ctttacgtga
    51541 ggacattttg actccagatc ggatgatgaa gggcacgccc ttaacgactt gacgacagcg
    51601 cgttttgggc tacgccggaa aatttgccaa caatttaccg caagccgcgc gtcatgtaca
    51661 tggaacatcc ttttgccgct tcagaaatct ctggatcatg ctcgcatgtt gcgcaatcta
    51721 ctcgcccgtc cgctgcgctt ttccttatac tgagactgag cgtcgattca cctgcaaacg
    51781 gcgcattttt agaataatcc tgaccttgtg cggaagagaa aacatgaaaa ttcgcgcctt
    51841 attggtagca atgagcgtgg caacggtact gactggttgc cagaatatgg actccaacgg
    51901 actgctctca tcaggagcgg aagcttttca ggcttacagt ttgagtgatg cgcaggtgaa
    51961 aaccctgagc gatcaggcat gtcaggagat ggacagcaag gcgacgattg cgccagccaa
    52021 tagcgaatac gctaaacgtc tgacaactat tgccaatgcg ctaggcaaca atatcaacgg
    52081 tcagccggtg aattacaaag tgtatatggc gaaggatgtg aacgcctttg caatggctaa
    52141 cggctgtatc cgcgtctata gcgggctgat ggatatgatg acggataacg aagtcgaagc
    52201 ggtgatcggt cacgagatgg ggcacgtggc gttaggccat gtgaagaaag ggatgcaggt
    52261 ggcgcttggt acaaatgccg tgcgagtagc tgcggcctct gcgggcggga ttgtcggcag
    52321 tttatctcaa tcacaacttg gtgatctggg cgagaaatta gtcaattcgc aattctccca
    52381 gcgccaggaa gcagaagccg atgattattc ttacgatctt ctgcgccaac gcggcatcag
    52441 cccggcaggt cttgccacca gctttgaaaa actggcaaaa ctggaagaag gtcgccaaag
    52501 ctcaatgttt gacgaccatc ctgcatccgc cgaacgcgcc cagcatattc gcgatcgtat
    52561 gagcgcggat ggggttaagt aagtcagaca taccgatcta caacataatt gtaggtcggt
    52621 aacgcctgaa tccccgatca gagtagtgat ttcactttat ttagcaaaac ggctacatca
    52681 tccggtcggg tatatcccgt atcagggtct ataatcgagc tgtaaacatg tggcataatg
    52741 cgcggcaccc ccgcctccag acaagttttc agaatcacac tgaagttatc caaatcaatc
    52801 ccgccagtcg gctcaatcag cgtcatacca ttgcgcgccg ccgtggtcgc cagcgcgtat
    52861 agctccggaa gcgacctctc gccgcccatc ggaaagaact tcgccgcgtg tgcgcccata
    52921 tctagcatca ttcgcaccgc cgtatcgcag gagacgcggg caggcgtacc ctggctgctg
    52981 ctaacgccgg tggaaatcag cacttcgccc ggcgtccccg tcgggctaac cagcgcgttg
    53041 acatgggtct gctcaccgcc cgtagccgca agcgcgcctg ccgcgaaacc acaaccggta
    53101 aaggtctggt taacgtgtgc tggatgaatc tgcgccgcaa tcatcgcagc tttgtaatac
    53161 tgcgccgggt cacccgcccc cagacctact gaaatggacg gtatttccgc catccaacgt
    53221 ttaacttcct ggatcccctc atccaccgag gagaactgcg cggaaagcac gccaatcact
    53281 gcgtggcctt cggcggcgtc aaagatttca cgggcattgg cgatatcttt cgccagcaca
    53341 ttaattgcca cgcgattacg atagaaatta atcttttgca tgatctgcaa tctccttcag
    53401 tcgcgccacg ataagtgcca tttccccttc cgccaccgta cgcggatcaa ggctaaaaac
    53461 gccctggtgg aggttatacc gccgtgcata aatcgcgata tcgccaccac gcagttgcgc
    53521 ttcgacgacg cgagcgtcaa ctcccaattc ctgcgcattt actcgaatac gaatacgcca
    53581 gattgcacgc ccggcttcat cctgctcaat atcagccgtt aacccgtgaa tcgcagaaat
    53641 cgcttcaacc actggctgga gctgttccgc ggtgatgact gcctgcccct ggtgataatt
    53701 ctccagcgcg taaaccagcc caaccatgtt ctccttgccg attttcatcg ccctggcaat
    53761 gccgtgatgc tgcgctttgc aggctgcaat ccagattttt ttaccagtga taaacccgga
    53821 ggtcggcgcg ttaaaggctt ttgcgccgct gtagaccacc atatccgctc cgctcaccac
    53881 ccaggcacgt aaatcctctt cggcggcggc atcgacaatc agcggcaggt tgtacatctg
    53941 cgcgacatgt gcgaagtcct cgatgttcaa cattcccttc tgcacgcagt gatgcgactt
    54001 cacatacagc agcgcgacgg tcgcgtcggt aatggcactc tccagctgcc agagagccgc
    54061 caggttactt gaacccacct ccacaacgcg cccgccacct aagcggatcg cgctgaggat
    54121 cgatgcaccg taatcgacgt tatggccgcg cagcatcacc acttcattgg ccatgccgga
    54181 gctatccggc atgagcgcca cccgggcctt gtcgccgcgt gtaatggcgg cggcgacagc
    54241 gatggcgatc cctgctgagg cacaggaggt aacgtagcta tcctccgccc cggtaaagcg
    54301 agagaccagc tcgccggttt tgtccaccag ctggtcaatc tccacgaaag aggatgccgc
    54361 gcgcgcggtg gcctgcatca cctccggcgc gacgctggag acgccgagaa tcgtcatctt
    54421 gccgcaggcg ttaatcacct gtttcagtcc cagttgttga tagatattct gcgtcatggc
    54481 ttacagcact cccagcagcg agcagaccac gctcaacgcc acaatcgaca gcagaatcgt
    54541 ggtgtaacgc ggaccctttt tcaccaaata gaagtagatg gcgaacactg ccgccagcgg
    54601 cagcaggccg ggcgcgatgg agtccagaat ctgctgtacc accacttcag agcctttcag
    54661 tgcgctaatt tttaaaggtg aggttatctt gacaaagctc gcggatagcg cgcccatcat
    54721 gataagcccc agtacgttag cgccgtagat aagctccttg atgcgccctc cctgcagcag
    54781 actgataatc gaatcgcgcc ccagcgtata gcccttgtgc accatgccgt agctgattgc
    54841 cagcgtaatc gccgggtaga gaatcagcgg caaaataccg cccatcgcgc tgccattggc
    54901 ggcgaacggg ataaaaatag caatcaacag cggcatcacc gccgcccaga tgatggagtc
    54961 gcccatcccg gccagcggcc ccatcaggcc ggttttaatc ccggtgatag aggcatcgtt
    55021 aatcgcctcg ccgcgggtct tttgctcttc catggcgatg gagatcccct ggatcaccgc
    55081 gccaaacgtc tgctctgagt tgaagaagtt cagatggcgt tttaacgcct ccacctgctc
    55141 ctccttttgc ggatagagct ttttgataat cggcgtcatc gaggcgcaga aaatcaggct
    55201 ctgtaaacgc tcataggagc tggaaacttc cgcgcccagc cagtagataa accacgcttt
    55261 ggtgatatcc gctttggtca gcgtcccgga ctcccgcgcg cgctcaacca gttcatgctg
    55321 cattacgtcg tcgctcatta tgccgctcct tcatttttcg ccaggccttt aatcaggaag
    55381 gccacgcagg tgccgaaaat cgccatcgcc atgatgtcca ccttgaggta cagcaccgcg
    55441 aagaatccgc cgataaacca cggcagcagg ctctttttac caatcaccat aatggtgatg
    55501 gcgaagccca gcgccgggag aatcccgccc atgatttcaa acgagtgggt cagccagtgc
    55561 ggcatcagct tgaggaaact ttccactacg ttctggccga agtagttggc ggcgaacacc
    55621 actgggaaac gtagtaccag ccccagcagc gccgggtaga gaaaggcgca gcgcataatg
    55681 gctgacatat tggccgtttc cgcgtgttta tcggccatat gcacccaggc cgcatttagc
    55741 gtgcgacgca actggtcgag gaatacgccg ataacgccaa atggaatcgc cagtgcaatc
    55801 gccaggttcg ggtccatatt ggccttaacg gcgataggaa tggcgataca ggccgccagc
    55861 gccgggtctg acggcacatt gccgcctggc gttgaggtca cacccagata gaccaactgc
    55921 atccccgcgc cgataatcat cgccgcaggc atattgccga gcagcaggcc gacaaagacc
    55981 gccaccacca ctggctgtaa cagcatggcg gagaaggtat agccaaggcg caaccgggca
    56041 aaccagtaat acagccccat caggcttgca aaaagtaagg tatccataat ttgttatccc
    56101 atgttcagag ggtcagaatt ttttcaggat atcgtccagc gactgcggtt tatcttccgg
    56161 gatggtctgg aaaacagcct taatgccgcg acttttcaaa tcgttaagaa tgccaacgtc
    56221 tttttcatcc agcgttatgt tctggaacac cgctttacgg tttggcccgc cgcctaaacc
    56281 gccaacctga atatcagcca cgtcaaagcc ctgctgcacc gcttcctgaa tcgccgccag
    56341 cgacgggaac agcaccagca cgttgccgtc gcccagctgg ttctctttcc acgcggccgc
    56401 gaagctctgg ttgctaaagc agtccacttt gatattcggc ggcgcggcca tcaggtagat
    56461 atttttcata aacggatcgg cgtccagctc gtcgctgacc accgcaatac ggttggcctg
    56521 agactgccct acccacttcg tcaccacctg tccgtggata agacggctgt caatgcgaca
    56581 taacacgatg tttgccatac gattttcctt actgttgtaa ttgacgaata tgggagacga
    56641 cgtccaggca actgttgcgc ccagcttcca ccagatcggc cacgcaggcg gtcagtgggc
    56701 catgttcgcg cttgtccagc gcctccagca gcagcgaggc attaagcccg gagatcaccg
    56761 ccaccggata atcggcgctc agccgcgccg ccacgttaga ggtggtgccg ccgataaaat
    56821 cggtcacgat aagcgaacct tccggcatgg ttttcaccac ggcttcgacg cgctggtaaa
    56881 actcgcccag cgtatcgacg ggcatcagcg cgatttccgt cacgccttcg atttcgccca
    56941 tcaccatgcg cagactgttg cagagctgca gcccccagcc gccgtgagtt agcagcagaa
    57001 tttcaggtaa cggatgaata ggtacagttg tggtcaaaat agcctccttt gctccagtgt
    57061 ttacatttca tcaggagcaa aggacgtgcc agaatttgtg tcacgcacag aggaaatgag
    57121 attggatggg gcgttaagcc ccgtaaacca ggggatcagc tgtagagcag ttcgtagata
    57181 taaaaatatt ctgcgtccga taaacggata gcgtaagcct cttcaatcgg caaaaaggag
    57241 gatttgatga cgctaaaggc acgagcgtcc agatcaagcc ggttttctag cgccatctgt
    57301 aacggtttgc ggttaatcac gatacgctcg accatgcagc agcagtggat cagaaaacgt
    57361 agtgtcacct ggcggctcgg tttcagggag agcgtgttgg ttaagtagtt cagaacatcc
    57421 tcgatctctt tcagaattcg ctgcgggttg agcaccgaaa tatggttgat gatgctctcc
    57481 atggtcagcg cgctgataaa gcgcatggcg ctgcgctcca tctccagtcg gcgctcgctg
    57541 cttgagagat ccggcgtcag caggctgagc accagctccg gcccttgctc ggaaaacagt
    57601 tcctccagcg agataaacgg tatatccggc agtcccggct ggaaggtgcc gacgatccct
    57661 gccagccgtt cactggcatt aagcgcctgc tgaatacgct ccaggctgcg cacctcgtta
    57721 tagtcgagaa tcaccatacg cgtgtcctgc gacatcagct cgccaaagct ctcctccagc
    57781 acctttttga tcttttccgc cgtccccatt ccggttatac atgagataac cagcactttg
    57841 ccaccgctct cttgctgcgg cgtgcagagc cgacaaggga tatttttact ctgcataagc
    57901 acagccaatt gcgatagatc gccagtttcg tagcttaaat ccagcccaac ctccagcagg
    57961 ctggtcagag tgatatttgg caacaacaga acgtcaatct ggaacagctt gctgatggtg
    58021 ctgccaaaat ggaccagcga tccgatatcc accatcagta tcagccgctg ccagcaccgg
    58081 tcctgaatca tccgggtcag ggtttccagg gtgtcatgca ccgactgctc aaatggcata
    58141 tcaattgcgt agaacagatc gcgctccagc acccggttca catattgcgc ctggctcgtt
    58201 gcggtggtcg caccgtgagc gattagaatc acgccgcaat ccgggctggt gtcgatgcgc
    58261 tggcggtagt ggcgacactc tttcaggaac aggcacagcc agaccacctc cgtcgccggg
    58321 cactgaatat gcaacaactc attgattttg cggcacagaa gcgtggcatt gtcatactca
    58381 tctttacagc gatccagaat caggctggat gaatagagtt gaggtataag ccctcgccgc
    58441 acatagccaa tcagcgcaag aaagtgttta cgtaacgggt tcgccaggtt ttctggcaat
    58501 gtaaatccta atacctgctc cacgtaaccg atcagcagcg tcacacgctc ctcaatttga
    58561 tcgccatagc gcggtggatg cgccgcacta tggcggctat aaagaccata ttcaaaaatc
    58621 gaactgagtt tgtttttcag gatagccagc gtttctgcgg gcggcacgtt actgttgcgc
    58681 agattgacat attcacgagt caggaaactg taaaacaggt cgctctcttc tatttccgcg
    58741 ctggtcgcca acgaattttt taacgcgggc aacgtacgcg catccacgtt cagacgatct
    58801 ttaccgccaa acaacgcatc gaccagcaga cgctgctctg gcgtggtatt aaacgacatc
    58861 tccgccagtc gtttatctaa ctctagcgta tcattacgct cggtcattcc cgacgcccac
    58921 gcctgcgcgc acaagaactg aatatcactt ttaagctggc cgatattgcc ttccaggggg
    58981 ttacttaaca accaatgcaa gagcgtttta tcaaggctta tggtacgttc aattttacga
    59041 ctttcacgct gaaagaagct tacaatcaat tcgagctgct cctcgaccga acgctggcga
    59101 atacccggta agtcaataca tacctggata cgccgctgga aggtacgcaa tagtgccgag
    59161 ttgaccgact ctgtagtggc gcaaataagg cgcaccgaaa ttgaatatgt tggcccactt
    59221 gaaccaagtg ggcggtattc acctttatcg agaatagaaa agagcttctc ttgtccttcg
    59281 tacgggaggc gatgcacttc atccagaagt aaataacctc cgtcagcttg ctccaccaat
    59341 cccgttttat tctcacttgc cccggtaaat gcccccttat ggtgaccaaa cagatgtgag
    59401 gaaagcaact ccggattatg agcatattcg gcacagttaa agtaaaccaa cggaggtggc
    59461 gaacctatgg tgtgcttgca agcgaagcaa tgcattaact cagcaaagaa tgttttgcca
    59521 acaccagatg caccggttaa cagcacatgt agtccgtggg gataaagcac cgctgcgcgg
    59581 cctttttcta ccgcatcacg gagactacgg tcgtatccga taagtccgga aaacggatca
    59641 tcatctgtat atttttcttt ctttggcaat aaactagcca ctgaatgaac tatgcattcg
    59701 caatcatcca gttttcgatt aatgagcaat tctagtgcgt gacgatgtag aaaaaaaaca
    59761 ggacgtccct gactttttac caccaggcct tcattccata attgattaag atctttacta
    59821 accgagttgc gtgccagccc aaggttaaaa ccaatcgcct cagcagtaaa tgctttctcc
    59881 ttcgctaaat cagacagttc cagcccatac gtcagccgct ccagctcctt gtgaataaca
    59941 tcaatccgtc tcatttcttt accgcttaaa aaacaatagt tgttcagaac atacactatt
    60001 tgtaaacgta agaatgagaa ctatcgggaa gaattaatgt tccttgtggc aatctggttt
    60061 ctgaatattc gtgttttaaa tattacttat ggtctgaaac aaccaggcag gtgaacagag
    60121 ctaagaaaaa gtagcgtaga aatataaaaa catatatcgc actgatgaat gtttcccggc
    60181 atgactatgc acaccgggaa atatttagta aattactcgc cctttttcgc cgcctgaata
    60241 tacagcatct ccagcgccag cgtcgccgca gccagagcag tgatttccga ctgatcgtat
    60301 gccggagcca cttccactac gtccatccca acgatgttga gatctttcag gccgcgtacc
    60361 agtttaatgg cgcgatcgga ggtcagaccg ccaattaccg gcgtaccggt tcccggcgca
    60421 aatgcaggat ccaggcagtc gatatcaaag gtcaggtaaa ccggcatatc acccacaatt
    60481 tgtttcacct gggcgataac gtcatccacg ctgcgatcgt tcacctggca ggcgtccagc
    60541 acggtaaagc cgttgtcttt atcaaattcg gtacgaatac caatctgcac ggaatgattc
    60601 ggatcgatca gaccttcttt cggcgcggta tagaacatgg tgccgtggtc aaattcacaa
    60661 ccgttcgcgt aggtatcggt gtgggcgtca aagtgtacca gcgccatttt accgaaatgc
    60721 ttcgcatgag cacgcagcag cggcagcgta acaaagtggt caccaccgaa ggagagcata
    60781 cgcttaccgg cagccagcag cttctcggcg tgcgcctgca gcttctcgct catctcacgg
    60841 gcatcgccga aagcatatac cagatcaccg cagtccacga cgttcagacg ctcacgcatg
    60901 tcgaaattcc acgggaagcg attgtgttcc caggccagat tcgtcgaaac ctgacggatc
    60961 gctgccggac cgtggcgacc accggcacgg ccagaggtgg ccatgtcgaa cggcacacca
    61021 gtaatcaccc agtcagcatc gctgtcatac ggctggaagt tcatcggcag gcgtaaaaaa
    61081 ccaaaggcgt tggaaaccag tgagttatcg tattgatgac ctaaggtgct catggatgga
    61141 ctcctattac aaagtcgata taaaaaaacc cttccgcgtc gttaggcccg acgaggaagg
    61201 gttggatttg cgaaacacaa gtttgtgcta attatcgcct taaatgggcg aggcatcaag
    61261 cgaggttgct atttccgaca cggtggcggc gcatagccat tgttatctgc cggaaaggct
    61321 tgtccagagc acggcggcag cgcgttttgc gccgggcctt gtaattcaaa ggcggcaaag
    61381 ccgattaccc cggtattacg cacatcgcct tgcgccgaat tggctgcgta ggaatcagca
    61441 acgttggcga actgaaaagc cgcttcggta tgtttatctt tgcggaatcc tttaatcgct
    61501 aacgaatctc cggcattcac aatatagccg ttgttattca gcgaaccttg cttgccgttc
    61561 agcacatcca tgccatcaac cgtagcaacg atctcgtagt tggtgttacg actgtaatta
    61621 cggacatata attgataatt cattccgact ctggcatgga caatatagcg tggttcatta
    61681 ttggatgaat cataaacacg cgtaataggt agagaattaa aattaccatc gcgaatagca
    61741 tattccagtt cgttaatacg aatgctataa acgcggtcat agccggaagg aacattagtc
    61801 gaataactaa taacgatcat ctctgcagga tcgcgccagg ctcgttcagc agatacgccc
    61861 tggaccgatg agtgcacatc cccaccccag gcggtgccga cattgcccga tgcactgcta
    61921 ttatactgcg cattactgga acaaccggcc agcagcacga ttaatgccac caacgcgcta
    61981 cgtactttcc attttttcat aaccgttccc tctgcattta attaatgcag cgattgtagg
    62041 gagattattt aataagaaaa gcagccagat tatttttaag aatatataaa aagaaagcgg
    62101 gccgatttac gtaaataaat cgacccgcca gcggaataat cttaattatt catcttcaag
    62161 ataagtataa ccgtacaaac ctgcctcgaa ctcttcaagg aactgttgtt gcagttcagc
    62221 atcaagatcg gttttcttca cttgatcgcg gaactgggtt aacagcgttt tcggatcgag
    62281 ctgtacatat tgcagcatgt ccgccacggt atcgccttcg tcagacagtt ctacttctac
    62341 gctaccgtca gggaacacga acacgtcaac cgcttcggta tcaccgaaca ggttgtgcat
    62401 attgccaagg atctcctgat atgcgccgac cataaagaaa ccgagcatcg gcggattctc
    62461 tggatcgtac tccggcattg gcattgtcgt ggcaatacca tcaccatcaa tatagtggtc
    62521 gatagcaccg tcagagtcac aggtaatatc cagcagcaca gcgcggcgtt ccggcacttg
    62581 atccagccct tccagcggca gaaccgggaa caactggtcg atcccccacg catccggcat
    62641 cgactggaac agcgagaagt tgacgtacat tttgtctgcc atacgttcct gcagctcgtc
    62701 gataatcgga cgatgagcac ggttttgcgg atccagttgc ttctgcactt catggcacat
    62761 gctcagatag agttgttctg cccatgcacg ttcttgcagg ctaaaggtgc cggaagagta
    62821 gccgatatga atgtcgtgca gatccatctg actgtcgtgt aaccattcac gcagagaacg
    62881 gcgagttccc ggttcgtgca tctcctgcca ggtttcccac atgctttgca gcgcacgcgg
    62941 cgcatcttct gcaggcgcgg tcggcaccgt gtattcgtta cgttccacgc cgatgatatt
    63001 agacaccagc acggtgtgat gcgcagtcac tgcacgaccc gattcagtga ttaccgtcgg
    63061 atgtggcaga ccgttttctt cacatgcatc accaatcgcc cagatgatgt tgttggcata
    63121 ttcattgagg ccgtagttca ccgaacagtc ggactgcgaa cgagtacctt cataatccac
    63181 gcccagaccg ccgccgacgt cgaagcactg aatattgacg cccagcttgt gcagttccac
    63241 atagaaacgc gccgattcac gaacgcccgt ggcgatatcg cgaatattcg ccatctgcga
    63301 accgaggtgg aagtgcagta gttgcaggct gtcgagacgc ccggcttcac gcagggtttc
    63361 aaccagttgc agtacctgag tcgcagccag gccgaacttc gatttttccc cgccggagga
    63421 ctgccattta cccgagccct gcgaagccag acgtgcacgc acgcccagac gaggaacgac
    63481 attcagacgt tctgcttcat ccagcacaat ggcgatttct gacatcttct caatgaccag
    63541 atagaccttg tggcccatct tctcgccaat taatgccagg cggatatatt cgcggtcttt
    63601 ataaccgttg cagacgatga cgctacgggt catgccagca tgcgccagca ccgccatcaa
    63661 ctctgctttc gagcctgctt ccagccccaa cggttcgcca gaatgaatca gggactcaat
    63721 cacgcggcgg tgctggttaa ctttgatcgg ataaacaagg aagtaatcgc cgttatagcc
    63781 gtaggattcc cgcgcacgtt tgaacgcggc gttaatggaa cgcaaacggt gctgcaggat
    63841 ctgtgggaaa cagaacagtg caggcagacg ctgaccctgt gcttcacgag ttttcactaa
    63901 ctgcgcgaga tcgacgcgag cttccgggac gtccgggtcc gggcacacgc tgatgtggcc
    63961 cagctcgtta acgtcatagt agttattgcc ccaccaggca atattgtaag tacgcagcat
    64021 cttgctggct tcctgggagc tcattgcaac ctcctgcatg gagcgtagta caccgtgttc
    64081 gcccgctgac gaaggcaaac ccatagacat gtcgtcagac atagcgaacc tcaaattatt
    64141 ttattaagtg taaaacagtt aacgactatc gcagcctgga actgcgataa caacccataa
    64201 gcacatggat tttccagcag tgaatgctga cgctccaact gcgcaaccgg tttctttttc
    64261 ataacattat taagcacata accgaacgta agtgtgacag ttcggcgaaa ccacgagaaa
    64321 actcttgttt ttacaagagc gcccttgttc agtcctcagt aactgtaacc agctcttgaa
    64381 tcctgagaag cgccgagatg ggtataacat cggcaggtat gcaaagcaga gatgcagagt
    64441 gcggggaacg aatcttcacc agaacggtga gacaggttaa gcagcagaca acggttcatt
    64501 atttcgtatc acctccacgg ccgcctgtta agacgaaccc acaagccaaa actctgattt
    64561 caacccggct ggaagtggca acacgaaaga aacgtcgtgt gctttttatt taagccgcgc
    64621 gccgcgtttt ataccccaca atggcagaaa attgcaaaag ataaatacgc agaatgccgg
    64681 cattgtcagg aaaaatttcc agccacgttt ttaacagaat gagacacgat tcaaaaaaaa
    64741 gtggaaatcg ggtgaagaat tgacctaaaa tagccatcca gatgttaatc catccatacc
    64801 gattaacact cagactgcca gtgtttttaa cctgcagagt cgtggtagga tccgctacca
    64861 cagaaaatcc acacaacagt ttgagctaac caaattctct ttaggtgata ttaaatatgg
    64921 caaaacacct ttttacgtcc gagtccgtct ctgaagggca tcctgacaaa attgctgacc
    64981 aaatctctga tgccgtttta gacgcgatcc tcgaacagga tccgaaagca cgcgttgctt
    65041 gcgaaaccta cgtaaaaacc ggcatggttt tagttggcgg cgaaatcacc accagcgcct
    65101 gggtagacat cgaagagatc acccgtaaca ccgttcgcga aattggctat gtgcattccg
    65161 acatgggctt tgacgctaac tcctgtgcgg ttctgagcgc tatcggcaaa cagtctcctg
    65221 acatcaacca gggcgttgac cgtgccgatc cgctggaaca gggcgcgggt gaccagggtc
    65281 tgatgtttgg ctacgcaact aatgaaaccg acgtgctgat gccagcacct atcacctatg
    65341 cacaccgtct ggtacagcgt caggctgaag tgcgtaaaaa cggcactctg ccgtggctgc
    65401 gcccggacgc gaaaagccag gtgactttcc agtatgacga cggcaaaatc gttggtatcg
    65461 atgctgtcgt gctttccact cagcactctg aagagatcga ccagaaatcg ctgcaagaag
    65521 cggtaatgga agagatcatc aagccgattc tgcccgctga atggctgact tctgccacca
    65581 aattcttcat caacccgacc ggtcgttttg ttatcggtgg cccgatgggt gactgcggtc
    65641 tgactggtcg taaaattatc gttgatacct acggcggcat ggcacgtcac ggtggcggag
    65701 cattctctgg taaagatcca tcaaaagtgg accgttccgc tgcgtacgca gcacgttatg
    65761 ttgcaaaaaa catcgttgct gctggcctgg ccgatcgttg tgaaattcag gtttcctacg
    65821 caatcggcgt ggctgaaccg acctccatca tggtagaaac tttcggtacc gagaaagtgc
    65881 cttctgaaca actgactctg ctggtacgtg agttcttcga cctgcgccca tacggtctga
    65941 ttcagatgct ggatctgctg cacccgatct acaaagaaac cgcagcatac ggtcactttg
    66001 gtcgtgaaca tttcccgtgg gaaaaaaccg acaaagcgca gctgctgcgc gatgctgccg
    66061 gtctgaagta atctttcttc acctgctttc aaaggccagc ctcgcgctgg cctttttctt
    66121 ttacctcacc gcggtggata ggcattcacg ccgcatccgg caaaaagctg cccgcacaat
    66181 aacatcattc ttcctcaaca cgttttatcg caaattatca tcactactga aaccgattac
    66241 accaataaca ccagccaaat atttgtaata ttttcatatt attattcagt tttcacagtt
    66301 gttacatttc ttttcagtaa agtcttaatt gcagataaca gcgtttaatc tatgatgata
    66361 taactcaatt attttcatgc acttaaacca taactaagat aaatgttagt gtaagcgatt
    66421 acactgatgt gatttgcttc acatcttttt acgtcgtact cacctatctt aattcacaat
    66481 aaaaaataac catattggag ggcatcatgc ctgacgctaa aaaacaggag cggtcaaaca
    66541 aggcaatgac ttttttcgtc tgcttccttg ccgctctggc gggattactc tttggcctgg
    66601 atatcggtgt aattgctggc gcactgccgt ttattgcaga tgaattccag attacttcgc
    66661 acacgcaaga atgggtcgta agctccatga tgttcggtgc ggcagtcggt gcggtgggca
    66721 gcggctggct ctcctttaaa ctcgggcgca aaaagagcct gatgatcggc gcaattttgt
    66781 ttgttgccgg ttcgctgttc tctgcggctg cgccaaacgt tgaagtactg attctttccc
    66841 gcgttctgct ggggctggcg gtgggtgtgg cctcttatac cgcaccactg tacctgtcag
    66901 aaattgcgcc ggaaaaaatt cgcggcagta tgatctcgat gtatcagttg atgatcacta
    66961 tcgggatcct cggtgcttat ctttctgata ccgccttcag ctacaccggt gcatggcgct
    67021 ggatgctggg tgtgattatc atcccggcaa ttttgctgct gattggtgtc ttcttcctgc
    67081 cagacagccc acgttggttt gccgccaagc gccgttttgt tgatgccgaa cgcgtgctgc
    67141 tacgcctgcg tgacaccagc gcggaagcga aacgcgaact ggatgaaatc cgtgaaagtt
    67201 tgcaggttaa acagagtggc tgggcgctgt ttaaagagaa cagcaacttc cgccgcgcgg
    67261 tgttccttgg cgtactgttg caggtaatgc agcaattcac cgggatgaac gtcatcatgt
    67321 attacgcgcc gaaaatcttc gaactggcgg gttataccaa cactaccgag caaatgtggg
    67381 ggaccgtgat tgtcggcctg accaacgtac ttgccacctt tatcgcaatc ggccttgttg
    67441 accgctgggg acgtaaacca acgctaacgc tgggcttcct ggtgatggct gctggcatgg
    67501 gcgtactcgg tacaatgatg catatcggta ttcactctcc gtcagcgcag tatttcgcca
    67561 tcgccatgct gctgatgttt attgtcggtt ttgccatgag tgccggtccg ctgatttggg
    67621 tactgtgctc cgaaattcag ccgctgaaag gccgcgattt tggcatcacc tgctccaccg
    67681 ccaccaactg gattgccaac atgatcgttg gcgcaacgtt cctgaccatg ctcaacacgc
    67741 tgggtaacgc caacaccttc tgggtgtatg cggctctgaa cgtactgttt atcctgctga
    67801 cattgtggct ggtaccggaa accaaacacg tttcgctgga acatattgaa cgtaatctga
    67861 tgaaaggtcg taaactgcgc gaaatcggcg ctcacgatta atctcctcag gcttcctccc
    67921 atcgcggagg aagccacctc ttgcagtcat cttttcttcg ctctatcctc tgccgctatg
    67981 aaaacatccc gtctccctat cgccatccag caggccgtta tgcgccgcct gcgggaaaaa
    68041 ctcgcccagg ccaacctgaa gctagggcgt aactacccgg agccaaaact ctcttacacc
    68101 cagcgcggaa cctccgccgg aacagcctgg ctggaaagct atgaaatccg cctcaatccc
    68161 gttttgctgt tggaaaacag tgaagctttt attgaagaag tggtaccgca cgaactggca
    68221 catttgctgg tatggaaaca tttcggccgc gtagcgccac atggcaaaga gtggaagtgg
    68281 atgatggaaa gcgtgctggg cgttcccgcc cgtcgtacgc atcagttcga actgcaatcc
    68341 gtgcgtcgca acaccttccc ctaccgctgc aagtgccagg agcatcagct taccgtacgc
    68401 cgccataatc gcgtagttcg tggcgaggcc gtctatcgct gtgttcactg cggtgaacag
    68461 ctggttgcga aataaccatc tgaactatca ggaactttcc tgatctggct gattgcatac
    68521 caaaacaact ttcgctacgt tgctggctcg ttttaacacg gagtaagtga tgtaccgtta
    68581 tttgtctatt gctgcggtgg tactgagcgc agcattttcc ggcccggcgt tggccgaagg
    68641 tatcaatagt ttttctcagg cgaaagccgc ggcggtaaaa gtccacgctg acgcgcccgg
    68701 tacgttttat tgcggatgta aaattaactg gcagggcaaa aaaggcgttg ttgatctgca
    68761 atcgtgcggc tatcaggtgc gcaaaaatga aaaccgagcc agccgcgtag agtgggaaca
    68821 cgtcgttccc gcctggcagt tcggtcacca gcgccagtgc tggcaggacg gtggacgtaa
    68881 aaactgcgct aaagatccgg tctatcgcaa gatggaaagc gatatgcata acctgcagcc
    68941 gtcagtcggt gaggtgaatg gcgatcgcgg caactttatg tacagccagt ggaatggcgg
    69001 cgaaggccag tacggtcaat gcgccatgaa ggtcgatttc aaagaaaaag ctgccgaacc
    69061 accagcgcgt gcacgcggtg ccattgcgcg cacctacttc tatatgcgcg accaatacaa
    69121 cctgacactc tctcgccagc aaacgcagct gttcaacgca tggaacaaga tgtatccggt
    69181 taccgactgg gagtgcgagc gcgatgaacg catcgcgaag gtgcaaggca atcataaccc
    69241 gtatgtgcaa cgcgcttgcc aggcgcgaaa gagctaacct acactagcgg gattcttttt
    69301 gttaacccct accccacgcg tacaaccgcg tggggagacg acgcggattt ttaactatgc
    69361 gtatcccccg catttatcat cctgaaccac tgaccagcca ttctcacatc gcgctttgcg
    69421 aagatgccgc caaccatatc gggcgcgtac tgcgcatggg gccggggcag gcgttgcaat
    69481 tgtttgacgg tagcaaccag gtctttgacg ccgaaattac cagcgccagc aaaaaaagcg
    69541 tggaagtgaa ggtgctggaa ggcaagatcg acgatcgcga atctccgctg catattcacc
    69601 tcggtcaggt gatgtcgcgt ggtgaaaaaa tggaatttac gatccagaaa tcgatcgaac
    69661 tcggtgtaag cctcattacg ccactttttt ctgagcgctg cggcgttaaa ctggatagtg
    69721 aacgtctgaa caagaagctc cagcagtggc agaagattgc aattgctgcc tgtgagcagt
    69781 gtggtcgtaa ccgggtgccg gaaatccgcc cagcgatgga tctggaagcc tggtgtgcag
    69841 agcaggatga aggactgaaa ctgaatcttc acccgcgcgc cagtaacagc atcaatacgt
    69901 tgccgttacc ggttgaacgc gtccgcctgc tgattggccc ggaaggcggt ttatcggcag
    69961 atgaaattgc catgactgcc cgctatcaat ttactgatat cctgttggga cctcgcgttt
    70021 tgcgtacaga gacaactgcg ctcaccgcca ttaccgcgct acaagtacga tttggcgatt
    70081 tgggctaacg gagaagaata atgatcaagc tcggcatcgt gatggacccc atcgcaaaca
    70141 tcaacatcaa gaaagattcc agttttgcta tgttgctgga agcacagcgt cgtggttacg
    70201 aacttcacta tatggagatg ggcgatctgt atctgatcaa tggcgaagcc cgcgcccata
    70261 cccgcacgct gaacgtgaag cagaactacg aagagtggtt ttcgttcgtc ggtgaacagg
    70321 atctgccgct ggtcgatctc gatgtgatcc tgatgcgtaa agacccgccg tttgataccg
    70381 agtttatcta cgcgacctat attctggaac gtgccgaaga gaaagggacg ctgatcgtta
    70441 acaagccgca gagcctgcgc gactgtaacg agaaactgtt taccgcctgg ttctctgact
    70501 taacgccaga aacgctggtt acgcgcaata aagcgcagct aaaagcgttc tgggagaaac
    70561 acagcgacat cattcttaag ccgctggacg gtatgggcgg cgcgtcgatt ttccgcgtga
    70621 aagaaggcga tccaaacctc ggcgtgattg ccgaaaccct gactgagcat ggcactcgct
    70681 actgcatggc gcaaaattac ctgccagcca ttaaagatgg cgacaaacgc gtgctggtgg
    70741 tggatggcga gccggtaccg tactgcctgg cgcgtattcc gcaggggggc gaaacccgtg
    70801 gcaatctggc tgccggtggt cgcggtgaac ctcgtccgct gacggaaagt gactggaaaa
    70861 tcgcccgtca gatcgggccg acgctgaaag aaaaagggct gatttttgtt ggtctggata
    70921 tcatcggcga ccgtctgact gaaattaacg tcaccagccc aacctgtatt cgtgagattg
    70981 aagcagagtt tccggtgtcg atcaccggaa tgttaatgga tgccatcgaa gcacgtttac
    71041 agcagcagta acccacctta gcgagaagga tctcgttgag actctgagtg acagcgccct
    71101 tctttccacg catactgggc gctgttgctt ttttgaacca ggaaacagaa cctctgacaa
    71161 tgaatttaca gcatcacttt cttattgcca tgcctgctct ccaggatccg attttccgtc
    71221 gttccgtggt ctacatttgc gaacataata ccaatggtgc aatggggatc atcgtcaaca
    71281 agccgctgga aaatctcaaa attgaaggga ttctggaaaa gctgaagatc acgccggagc
    71341 cgcgtgatga atcaatccgt ctggataaac cggttatgct cggcggtccg ctggctgaag
    71401 atcgcgggtt tattttgcat actccgccct ccaattttgc ttccagcatt cgcatttcag
    71461 acaacacagt gatgaccact tcccgcgatg tgctggaaac gctcggcacc gataaacaac
    71521 cgtctgacgt attggtggct ctgggttatg cctcctggga aaaaggtcaa ctggaacaag
    71581 aaattctcga taacgcgtgg ctaacggccc cggcggatct gaatattctg ttcaaaacgc
    71641 cgattgccga ccgctggcgc gaggcggcaa aactgattgg tgtggatatt ctcaccatgc
    71701 ctggtgtggc agggcacgcc tgatgagtgg aaccttactc gccttcgact tcggcaccaa
    71761 aagcattggc gtagcggtcg gccaacgcat taccggcact gctcgccctt tgcctgcaat
    71821 taaagcacag gacggtacgc cggactggaa cctcatcgaa cgtttactga aagagtggca
    71881 gccggacgaa atcatcgtcg gtttgccgct gaatatggac ggcaccgagc aaccattgac
    71941 tgccagagcg cgtaaatttg ccaaccgtat tcatggtcgt ttcggtgttg aagtaaagct
    72001 ccatgacgaa cgtcttagca ccgtggaagc ccgttccggt ctgtttgaac agggcggcta
    72061 tcgggcgctc aacaaaggca aagtcgactc tgcctctgcg gttattattc tcgaaagcta
    72121 tttcgagcag ggatattaag gcgatctaaa agcctggcgg atagtcgtta ccgccatctt
    72181 gccggatgcg gcgtgaacgc cttatccagc acacatctgg cagcggctgt aggtctgata
    72241 agacgcgtta gcgtcgcatc agacatttat tgcctttata ggccctataa acttgcgcat
    72301 cgggcatggc aacgtcacaa acgcccttcc cccacccgct gctgataact ctgctgaaac
    72361 gttaacatcc ccacctgctg cccggtttga ataacatgcg gtaactggtg ggttttccct
    72421 tcgcgaatca aattccccac cgcgggagtg ttaatcaata attcaaacag cgccacgcgt
    72481 ccttcctgtt tatccacttc cagcttttgt gacaacacgg cccgtaaact acctgccagt
    72541 tgattacgta cgggatcttt ttcctgcgcc ggaaatgaat ccaccagtcg ctcaactgcc
    72601 tgcgcggcac cacgcgtatg taatgttgcc agcaccaaat gcccggtttc tgccgccgtc
    72661 agtgccagac ggattgtctc gctgtcacgc agctctccga gcaaaatcac atcaggatct
    72721 tcccgcaatg cggcccgcaa tcccgatgcg aacgtcatac agtgcaaacc aatttcccgc
    72781 tgctggatca aacatcgctg gctggcatag atatattcaa caggatcttc cagcgtcaga
    72841 atatgcgcat cggcatgttg attgagatag ccaaccatcg ccgccagcgt ggtagatttg
    72901 ccgctccccg tcgcccccgt caccagaatc aggccattct cgctcttgag taattccggc
    72961 aataccgttg gtgcgccaag ctgttcgagc tgtggacagt gcgaaggtaa caaccgtaat
    73021 gccagagaaa taccttgccg ttgcgcgaac gcactgccac gcaaccgctg gttttccgcc
    73081 agcgacacgg caaaatccag ctggccattt tccagcaata ttgcccgctg atcgtcatcc
    73141 agccactccc gcagtagctc ttcgacgtcc ggcgcatcaa acggcgcagc ttccattagc
    73201 ccgcgaatgc gccatcgtgc gggccaggcg ctgcacaggt gtagatccga gacgttatgc
    73261 tttacactaa gggccacaat ttcttccata ttcatactaa gatcctcgga aaatgaacga
    73321 tattgcgcat aacctggcac aggtccggga caaaatctca gcggctgcaa cgcgttgcgg
    73381 ccgttctcca gaagaaatta cgctgcttgc agtcagtaaa acaaaacctg cgagcgccat
    73441 cgcagaagcc attgatgccg ggcagcgtca atttggtgaa aactacgttc aggaaggggt
    73501 agataaaatt cgccactttc aggaactggg cgtaacagga ttagaatggc attttattgg
    73561 cccgttgcag tctaataaaa gccgcctggt ggcagagcat ttcgactggt gtcataccat
    73621 cgaccgtttg cgcattgcta cccgcctcaa cgatcagcgc ccggcagaac ttccccctct
    73681 taacgtactg attcaaatta atattagtga cgaaaacagt aagtccggga ttcaactggc
    73741 agaactggac gagctggcag cggcggtcgc tgaactaccg cgtttacgtc tgcgcgggct
    73801 gatggcaatc cctgcgcctg agtcagaata tgtaaggcag tttgaagttg cacgccaaat
    73861 ggctgtagca tttgccggac tgaaaacgcg ctacccgcat atcgacacgc tctctctggg
    73921 aatgtcggac gatatggaag ccgccattgc ggcaggtagc acgatggttc gtatcggcac
    73981 tgcaattttt ggtgcgcgtg attactctaa aaaataagga attaaaggaa cgccatgaat
    74041 acgttgactt tcctgctttc aacggtcatt gagctgtata ccatggtgct gttattacgc
    74101 atctggatgc agtgggctca ttgtgatttt tacaacccct tctcacagtt tgtagtgaag
    74161 gtaacgcagc cgattatcgg gccactgcgc cgcgttattc cggcaatggg tcccattgat
    74221 agcgcctcgc tgctggttgc gtacattctc agttttatca aagccatcgt gctgtttaaa
    74281 gtggtgacct tcctgccaat catctggatt gccggtttac tgattctgct gaaaaccatc
    74341 ggcctgctga ttttctgggt cctgctggtg atggcgatta tgagctgggt aagccagggt
    74401 cgtagcccga ttgaatacgt gctgattcag ctggccgatc cgctgctgcg cccgattcgc
    74461 cgcctgctac cggcaatggg tgggattgat ttctcgccga tgatcctcgt tctgctgctg
    74521 tatgtcatca atatgggtgt cgcagaagta ttacaggcaa ccggaaacat gctgctgccg
    74581 gggctgtgga tggcgttatg agtgccgtaa cagttaatga tgacggtctg gttttacggc
    74641 tctatattca gccgaaagcc agccgtgatt ctattgtcgg tttacatggc gacgaagtta
    74701 aagtcgccat taccgcgccg ccggttgacg gccaggccaa cagtcatctg gtgaagtttc
    74761 tcggtaagca attccgggtt gccaaaagcc aggtggtgat tgaaaaaggc gaacttggcc
    74821 gccacaaaca aattaaaatc attaatccgc aacaaatccc gccagaaatc gcggcgttaa
    74881 ttaattaggt atcctatgca aaaagttgtc ctcgcaaccg gcaatgccgg taaagtgcgt
    74941 gagctggcgt cgctgcttag cgacttcggt cttgatatcg tggcccaaac agacctcggc
    75001 gtagattccg ctgaagaaac tggcctgacc tttatcgaaa acgcgattct gaaagcgcgc
    75061 catgcggcaa aagtgaccgg tttaccggca attgccgacg actctggtct ggcggtagat
    75121 gtgcttggcg gcgcgccggg catttactcc gcgcgttatt ccggtgaaga cgcgaccgat
    75181 ctaaagaatc tgcaaaaact actggaaaca ctgaaagacg taccggacga ccaacgtcag
    75241 gcgcgtttcc actgcgtgct ggtatatctg cgtcacgcgg aagatccgac tccgctggtg
    75301 tgccacggta gctggccggg cgtgattact cgtgaaccag cgggcactgg tggctttggt
    75361 tatgatccaa tcttcttcgt accttccgaa gggaaaaccg ctgccgaact gacccgcgaa
    75421 gaaaagagcg ccatttccca ccgtggtcag gcattgaaac tgctgttgga cgctttacgt
    75481 aatggttaaa ttaccgccgc tgagtctcta cattcacatc ccgtggtgcg tgcagaaatg
    75541 cccgtactgc gatttcaact ctcacgcgtt gaaaggagaa gtgccgcacg acgattacgt
    75601 tcagcatctg ctttgcgatc tggacaacga tgtggcttac gctcagggcc gtgaagtaaa
    75661 gactatcttt attggcggtg gtacgccgag cctgctttcc ggcccggcga tgcaaacgct
    75721 gctggacggc gtgcgtgcgc gtttgccgct ggcagcggat gcagaaatta ctatggaagc
    75781 gaaccctggt acggtagaag ccgatcgctt tgtcgattat cagcgtgctg gtgtgaaccg
    75841 catctctatt ggtgtgcaga gttttagcga agaaaagctg aaacgacttg ggcgcattca
    75901 tggcccgcaa gaagcgaaac gagcggcaaa gctggcgagc ggtttagggt tacgtagctt
    75961 taaccttgat ttgatgcatg gactaccgga tcaatcactg gaagaggcgc ttggcgatct
    76021 acgccaggcc attgaactga atccgccgca tctttcctgg tatcaactga ccatcgaacc
    76081 caatacgctg tttggttcgc gaccaccggt gctgccggac gacgatgcgt tgtgggatat
    76141 tttcgaacag gggcatcagt tattaaccgc agcgggttat cagcaatatg aaacttccgc
    76201 ttacgccaaa cccggttatc agtgccagca caatctcaac tactggcgct ttggcgacta
    76261 catcggtatt ggctgtggcg cgcacggcaa agtgaccttc ccggatgggc gcattctgcg
    76321 taccaccaaa acgcgtcatc cgcgtggttt tatgcaggga aggtatctgg aaagccagcg
    76381 tgatgtcgaa gctgcagata agccgtttga gttctttatg aaccgctttc gcttgctgga
    76441 ggccgcgcca cgcgcagagt ttattgcgta taccgggctt tgcgaagatg tgattcgccc
    76501 acagttagac gaggcgattg cccagggtta tctcaccgaa tgtgcggatt actggcagat
    76561 aacggaacat gggaagctgt ttttaaattc gctgctggag ctttttctgg ctgagtaaac
    76621 ttgtattgcc ggatgcggcg tgaacgcctt atccagccga catgtggcag cggttgtagg
    76681 tctgataaga cgcgcaagcg tcgcatcaga cgttgattgc cggatgcggg gtcaacgccg
    76741 catcctgcta caaatcgtgc actatatcaa acttacttaa tcaccccatt gcgccgcagt
    76801 tgttcggtat cttttttcca gcgttcatta gcttggttga tatcgtcaat tttcatcaaa
    76861 atcgcgactt ttttactgtt tatttctgaa actttcatcg ttaacggata ttgccctttt
    76921 tcgagcgtta cccagtcatc ctgcaattta cggctaagtt tttgtgattg cagaaaagtc
    76981 tgtcgccgtt gttcgttgat atcgaaatct cgtttctgct gaatcggcac ttcataacac
    77041 tcttcactct gtttatgaca tgccgcaatc gccggttgat aaacctcttt gtcatattta
    77101 accgcgaacg cctcgctatc gttctgttta ttaaactcat cacgctgttg gtgaattttt
    77161 ttaaaggcgt cttcgcgggt catttgctta ccgtttgcat cttttcccca atatgcatcc
    77221 gctgctttct gcgccgccac catttgctta tcaagcgctt tcacttcctt ttccagcgca
    77281 ggaatcgagt tcttctgggt attcaacgca gattcaagct gactaaagcg ataattgaaa
    77341 tcttcgctat tcacgatcag atatttatta ttcgttttga tatcgtcgac cacccgccca
    77401 cgatcgctgg ctgccgcctg aaaagagtaa aagttcaccg accagccaga cgcgggcgtt
    77461 cctttactgg ttaacatcgc cgagaatttt accggtttat ctttcgtcca ggtctgttcg
    77521 agcagttcgt aatctgccaa ctgaccgacc caggtataga gatcgtcact ggaagagaca
    77581 tcgccttccg ctgaccaggt ggcctgatta cccttagcat caagattttt taaggtgata
    77641 gcatcaagct tgagaatgcc gtgatactgc tttttgaatt gatcttttaa gatattttca
    77701 gttggcggtt cgccatctgc ccaggcatta ccagtcatca acataagcag tgccgtgcca
    77761 acaatccatt gctttttcac ccgaaaaacc tcacgcggaa taatttattc cggtgattat
    77821 cattagggta attaaaatta gcaatggacg tgagtctgaa gtgaaaaagc cccggcacga
    77881 taccggggcg aggcgattag tactgattga agatctgctg gatctgctgc ggatctttgg
    77941 tttgcgtcag agccagttgc agcagaacgc gcgctttttg cgggttcagc gtgccagagg
    78001 cgacgaagcc gtatttcgca tcatccactt cggcatcctg agtggtagcg cccgtcggta
    78061 cgcgggaaga acgcacgact gcagtaccgt ttttcgcggc ggtcgccagc gtgtcgaaca
    78121 cagatttata caggttgccg ttacccacac cagcgctaac gatgccatca tagcccgcat
    78181 ctaccagtgc tttagccgga agatcggatg cgttagcgta gttataaaca atgccgactt
    78241 tcggcagttc attcagctta gagacatcga atggcgtgtc gctggtatgc ttacgtgccg
    78301 gggtacgctg gtagtcaatc ttaccgttgt gaatgtaacc cagaggaccg tagttaacag
    78361 acttgaaggt cgctacgtcg gtggtgttgg ttttggtgac gtcacggcca tcaagcacgg
    78421 tgtcattcat cactaccagc acgccacggt tggcggaggc tttatcagct gcggtcacta
    78481 ccgcgttata caggttgaat ggaccgtctg cgctcataga cgtggacgga cgcattgcgc
    78541 cgaccatcac caccggtttg tcgcatttca ccgtcaggtc gaggaagtaa gcagtttctt
    78601 ccatcgtgtc ggtaccgtgg gtaatgacga agccgtcggt cttatcgcag tcggtgttaa
    78661 tttttttcgc cagtgtcagc cagacattat cgttcatgtc ctgggagccg atattcacta
    78721 cctgctcgcc tttaacgttc gcaatgtcct tcagttgcgg caccgcatta accagatttt
    78781 ctacgccaac tttacccgct gtgtagttag atttggttgc ggagtcacca ccaccggcaa
    78841 tggtcccgcc ggttgctaaa atggtgatat tgggtaatgc caatgctgca ccactaaaac
    78901 ccataaccag tgcggcaagt gccgtctttt tgaaaaactc catttcattc ctccagttac
    78961 gtgaacgcta cgcattatcc cttagctttg tatgggaaat ttgacgttaa acaatttaca
    79021 acgtgaatat attttggaga tctacaaagt tagaggcagg taacaaaacg aagaattaaa
    79081 cggcataaaa aagtattatg ccgtcttaaa atagaggatt attttaaatt cccgaccagg
    79141 gctttgcggc tatcttccag agtcacaaca cggctacaaa catctttgcc aaactgctgg
    79201 aaatcttttt cctgcttttt ccactcggtt tggattgagg attgcagccc ccccaggctt
    79261 cccagcacat tctgtaatgg gttaccgccg cttttcaaca ccgctttcgc gcccatttca
    79321 ttaatgctgt cctgtaaaat tccacccatt gcctgattca ctaattgctg gccttcggcg
    79381 cgaacctgat caatggcttt atagtgaaac gtcaggccat cgctgcgcgt ttcgataatg
    79441 cggttcatct gctctttcag ctgcgcatca agtttggtca gacggctgcg cattttgctg
    79501 ctttcgccca tctcctgaac gataatttta tccagcgcaa tacgggcttt ttcgacgcgg
    79561 cttttcgcgc cttcatcaat ccacggcagc gtgctgcgta gttcagcctg ataatccttc
    79621 gcctgctcgc gctgggcggc attcagggaa tattgcttac cgttatacat cacgttgccg
    79681 tctggcgtga tcaccagatt gccgttttcg cccttcacct gcacggtttg cgggctgaca
    79741 atcacatcgt cacgcggcgt gacgctgcac tggtagtcgg cgtgagcggt cattgccgtc
    79801 actgaaagtg ctgccgccag cagcattttg cgcatcatag tcttccctca agaaaaaatc
    79861 aggccagcat ttgctggccc cagattgata acaaagtacg cgttttccat gccggatgcg
    79921 gcgtaaacac cttatcccgc ctactcgatc gtgcatcttt ccaggcctga taagcgtagc
    79981 gcatcaggca gttttgcatt tgtcatcgcc cgtatgcttt cttagtccca ccaaacgtcg
    80041 aaaagttcgc tggtgcgtac ctcatccagt ttgcgctctt ccagccactt acgcacaatc
    80101 gcctgatgtt cttcggtgca tttgccgatt tcctgcatgc agatcagacc ttcccaggcc
    80161 agataaccgc tgccgtcaaa ggccagtttg ttcggttcga taacctcgtt aataaaatca
    80221 tcaacggttt tatcaatctg ttcttccgat gtaccttccg ggaatcgcca tgccaccgaa
    80281 aatcctaatt cctggaattc gtcgatgtgc atttttttac gcagacgacg gctacggttc
    80341 tttgccatta tttcaccctc tcgaacatta agtcccatac tccgtgacca agacgatgac
    80401 cacgttgttc aaatttcgtc accggacgtg atgccggacg cggtacgtaa tcattgctct
    80461 ctgacaggtt tttataaccg tcaatagaag acatcacttc aagcatatgt tccgcataag
    80521 gttcccagtc ggtcgccata tggaatacgc cccccagctg cagtttgctt tttaccagtt
    80581 cggcaaacgg cacctgtacg atacggcgtt tattatggcg cgctttgtgc cacgggtcag
    80641 ggaaaaagag ctgcaccatg cgcaatgaat tgtcaggaat cattttatgc agcacttcaa
    80701 ccgcatcgtg acacatcacg cgcaggttgc ttaaaccttc ttcatgcgca gaagccaggc
    80761 acgcaccaac gcccggtgaa tgcacttcaa tgccgaggaa gtcctgctca gggcgatctt
    80821 tagccattgc caccagcgac gcccccatgc caaaaccaat ctcaagcgtc accggcgctt
    80881 cacggccaaa aagcgcgggg aaatccagca tatcttcgct gaactcaacg cccatcaccg
    80941 gccagtagtt ttccagcgca tgttcctggc ctttggtcag tcgcccctgg cggcgcacaa
    81001 aactacggat acggcgcagt gggcggccgt tttcatcaaa ttccggtgaa atgacgtcgt
    81061 ttttcataaa gatttagtcg cttgtgaaag tgttctgaaa acgggcatta tccaaagtta
    81121 gttgccggat gcaagcatga taaggccgtg gctgcggaaa gttccggttt acaccctgcc
    81181 gtcgctgtgc tgcaatcttg cccccaacaa cagtgaattc ggtgaccatg caagcgtcgc
    81241 aattttcagc ccaggttctg gactggtacg ataaatacgg gcggaaaacg ctgccctggc
    81301 aaattgacaa gacgccctac aaagtatggc tctcagaagt gatgttgcaa caaactcagg
    81361 ttgcgaccgt tatcccctat tttgaacgct ttatggcgcg cttcccgacg gtgaccgatc
    81421 tcgccaatgc gccgctcgac gaagttctcc acttgtggac cgggcttggc tattacgccc
    81481 gcgcgcgcaa cctgcataaa gcggcacaac aagtggcgac cttacacggc ggtaaattcc
    81541 cggaaacctt tgaagaagtc gcggcgttac cgggcgtcgg gcgttccacc gcaggcgcga
    81601 ttctctcgct ttctctgggt aagcactttc cgattctcga cggtaacgtc aaacgcgtgc
    81661 tggcgcgctg ctatgctgta agcggctggc ctgggaaaaa agaggtcgag aataaattat
    81721 ggagtttaag cgagcaggtg acgcccgcgg tcggcgtgga acggtttaat caggcgatga
    81781 tggatttggg cgcgatgatt tgtacgcgct cgaaaccgaa atgttcgctc tgtccgctac
    81841 aaaacggatg tattgccgcc gccaacaata gctggtcgct ttatccgggc aaaaaaccga
    81901 aacagacgct gccggagcgc accggctact ttttgctatt acagcacgaa gatgaagtat
    81961 tgctggcgca gcgtccgccg agcggattgt ggggcggttt atactgtttc ccgcagtttg
    82021 ccgacgaaga aagtttgcgg cattggctgg cgcaacggca gattgctgcc gataacctga
    82081 cgcagctgac cgcgtttcgc catactttca gccatttcca cttagatatt gtgcctatgt
    82141 ggcttcccgt gtcgtcattc accggctgca tggatgaagg caatgcgctc tggtataact
    82201 tagcgcaacc gccgtcagtt ggcctggcgg ctcccgtgga gcgtttgtta cagcagttac
    82261 gcactggcgc gccggtttag cgcgtgagtc gataaagagg atgatttatg agcagaacga
    82321 ttttttgtac tttcctgcaa cgtgaagcag aaggtcagga ttttcagctg taccccggcg
    82381 agctgggaaa acgcatctat aacgagatct ccaaagaagc ctgggcgcag tggcagcaca
    82441 aacaaaccat gctgattaat gaaaagaaac tcaacatgat gaatgccgag caccgcaagc
    82501 tgctggagca ggagatggtc aacttcctgt tcgagggtaa agaggtgcat atcgagggct
    82561 atacgccgga agataaaaaa taaaaacagt gccggagcac gcctccggca acttgcataa
    82621 aaacaaacac aacacgcacc cggaatgatg aaaaaatatc tcgcgctggc tttgattgcg
    82681 ccgttgctca tctcctgttc gacgaccaaa aaaggcgata cctataacga agcctgggtc
    82741 aaagatacca acggttttga tattctgatg gggcaatttg cccacaatat tgagaacatc
    82801 tggggattca aagaggtggt gatcgccggt cctaaggact acgtgaaata caccgatcaa
    82861 tatcagaccc gcagccacat caacttcgat gacggtacga ttactatcga aactatcgcc
    82921 gggacagaac ctgccgcgca tttgcgccgg gcaattatca aaacgttgct gatgggtgac
    82981 gatccgagtt cggtcgatct ctattccgac gttgatgata ttacgatttc gaaagaacct
    83041 ttcctttacg gtcaggtggt ggacaacacc gggcagccga ttcgctggga aggtcgcgcg
    83101 agcaacttcg cggattatct gctgaaaaac cgtctgaaga gccgcagcaa cgggctgcgt
    83161 atcatctaca gcgttaccat taacatggtg ccgaaccacc ttgataaacg tgcgcacaaa
    83221 tatctcggca tggtccgcca ggcgtcacgg aaatatggcg ttgatgagtc gctgattctg
    83281 gcgattatgc agaccgaatc ttcctttaac ccatatgcgg tcagccgttc cgatgcgctg
    83341 ggattaatgc aggtggtaca acatactgcc gggaaagatg tgttccgctc gcaggggaaa
    83401 tccggcacgc cgagccgcag tttcttgttt gatcctgcca gcaatattga taccggcacc
    83461 gcgtatctgg cgatgctgaa caatgtttat ctcggcggaa ttgataaccc aacatcgcgg
    83521 cgttatgccg tcatcaccgc ctataacggc ggcgcaggca gcgtgctgcg agtcttttcg
    83581 aatgataaga ttcaggctgc caatattatt aacaccatga cgccgggcga tgtttatcag
    83641 acgctgacga cccgccatcc ctctgcggaa tctcgccgtt atctttataa agtgaatacc
    83701 gcgcaaaaat cctaccgccg ccgataattc cattaaccgc ccctgacgat gctcaggggc
    83761 aaaaatgtta cccacatcac aatttcgttt tgcaaattgg gaatgtttgc aattatttgc
    83821 cacaggtaac aaaaaaccag tccgcgaagt tgatagaatc ccatcatctc gcacggtcaa
    83881 atgtgctttt tcaaacactc atccgcatca cgatgtgagg aaattaacat gaatcttaag
    83941 ctgcagctga aaatcctctc ttttctgcag ttctgtctgt ggggaagttg gctgacgacc
    84001 ctcggctcct atatgtttgt taccctgaag tttgacggtg cttctattgg cgcagtttat
    84061 agctcactgg gtatcgccgc ggtctttatg cctgcgctgc tggggattgt ggccgacaaa
    84121 tggttaagtg cgaaatgggt atatgccatt tgccacacca ttggcgctat cacgctgttc
    84181 atggcggcac aggtcacgac accggaggcg atgttccttg tgatattgat taactcgttt
    84241 gcttatatgc caacgcttgg gttaatcaac accatctctt actatcgcct gcaaaatgcc
    84301 gggatggata tcgttactga cttcccgcca atccgtatct ggggcaccat cggctttatc
    84361 atggcaatgt gggtggtgag cctgtctggc ttcgaattaa gccacatgca gctgtatatt
    84421 ggcgcagcac tttccgccat tctggttctg tttaccctga ctctgccgca tattccggtt
    84481 gctaaacagc aagcgaatca gagctggaca accctgctgg gcctcgatgc attcgcgctg
    84541 tttaaaaaca agcgtatggc aatcttcttt atcttctcaa tgctgctggg cgcggaactg
    84601 cagattacca acatgttcgg taataccttc ctgcacagct tcgacaaaga tccgatgttt
    84661 gccagcagct ttattgtgca gcatgcgtca atcatcatgt cgatttcgca gatctctgaa
    84721 accctgttca ttctgaccat cccgttcttc ttaagccgct acggtattaa gaacgtaatg
    84781 atgatcagta ttgtggcgtg gatcctgcgt tttgcgctgt ttgcttacgg cgacccgact
    84841 ccgttcggta ctgtactgct ggtactgtcg atgatcgttt acggttgcgc attcgacttc
    84901 ttcaacatct ctggttcggt gtttgtcgaa aaagaagtta gcccggcaat tcgcgccagt
    84961 gcacaaggga tgttcctgat gatgactaac ggcttcggct gtatcctcgg cggcatcgtg
    85021 agcggtaaag ttgttgagat gtacacccaa aacggcatta ccgactggca gaccgtatgg
    85081 ttgattttcg ctggttactc cgtggttctg gccttcgcgt tcatggcgat gttcaaatat
    85141 aaacacgttc gtgtcccgac aggcacacag acggttagcc actaattacg caaagaaaaa
    85201 cgggtcgcca gaaggtgacc cgtttttttt attcttactt caacacataa ccgtacaacc
    85261 gtttcatgcc atccgcatcg gtttcgctat aaacaccttg cagctccggc gaaaatcccg
    85321 gcaacaaatt caccccttct tccagtgcaa ggaaataacg ttgaaccgcc ccaccccaga
    85381 cttccccggg taccacgcaa agcacgccag gtggataagg caacgcccct tctgccgcaa
    85441 ttcgcccttc ggcatcacga atccgcacca actccacttc accgcgaata taagcgctat
    85501 gcgcatcctg ggggttcatc accactgacg ggaaactctg ctggcggaac atcgcttttt
    85561 gtaggtcttt gacgtcgaaa ctgacataca gatcgtgcat ctcctgacac aactggcgca
    85621 gggtgtagtc gcgatagcgc accggatatt tgttataaac gctcggcaac acctcagcca
    85681 gcggcgagtc atcctcaata tgctgttcaa attgcgccag catcgccacc agttgtgcca
    85741 gcttctcgtg gctttccgcc ggagttaata agaacagaat ggagttgaga tcgcacttct
    85801 ccggcacaat gccgttctca cgcagatagt gcgccagaat cgtcgccgga acgccaaagt
    85861 cgctatattc gccagtttcg gcattgatac ctggtgtagt gagtaacagc ttgcacggat
    85921 caacaaaata ctgatccgcg gcatatcctt caaagccgtg ccacttcgcc cccggctcaa
    85981 aactgaaaaa acggcggtcg ctggctaaca ctgatgtcgg ataatcctgc cacaatttgc
    86041 catcaacaac gggcgggata aacgggcgga acagcttaca gcgcgcaaga atagccttgc
    86101 gcgcttcaat ccctatctca acacactcag cccacagccg acgcccactc tccccttcat
    86161 gaattttggc gttaacatcc agtgcagcaa acagcggata gaaagggctg gtagaagcat
    86221 ggagcataaa ggcgttattc aaccgcttat gcgggcaaaa acgcgcctgt ccgcggatat
    86281 ggttatcttt tttatggatc tgcgacgtct gtgagaatcc agcctgctgt ttgtgcaccg
    86341 actgggtcac aaaaatcccc ggatcgtttt cgttaagttc taacagcagc ggcgagctat
    86401 ccgccatcat cgggataaat tgttcgtaac cgacccacgc ggaatcaaac agaatgtaat
    86461 cacacagatg cccaacggta tcgatcacct gacgggcgtt atagacagtt ccgtcatagg
    86521 ttcccagctg aataatcgcc aggcgaaacg ggcgcggcag ctcggctttt tctggcgcaa
    86581 cgtcgcgaat ttgctggcgc agatactctt cattaaaaca gtgcgcatca ataccgccaa
    86641 tgaaaccaaa cgggttgcgt gaagcttcca gatagaccgg cgtcgccccc gcctgaatca
    86701 gcgcgccgtg atgattcgac ttatggttgt tacggtcgaa gagcaccaga tcgccacgcg
    86761 ttaacagcgc attcgtcacc actttattcg ctgccgatgt gccgttcagc acaaaatagg
    86821 ttttatcggc atgaaagact ttggctgcga atttctgcgc atctttcgcc gatccttcat
    86881 gaataagcag atcgcccaat tttacgtcag cgttacacat atcggcgcga aagacgttct
    86941 caccaaagaa atcgtaaaaa tggcgtccgg caggatgctt tttaaaaaac gcaccatgtt
    87001 gatgtccagg gcaagcaaag gtgctgttgc ccatctcaac gtactgcgtc agcgtgtcat
    87061 aaaacggtgg cagcaaattc tcttcatact gacaggctgc ggattccagc tccagccact
    87121 gctgctcgtt gccgttgatt accgccgtaa cgcccgcagg taattcaaca gcatgttcgg
    87181 aatacaaaaa caccggtaga tgaaaaccgg tgcgcttaag caacgcaaga atgccactgc
    87241 gactatccgc agcggtaatg acgactgccg cgacgtccgt aaaatcagta tctcccaacg
    87301 ccaccacgcg acgatgagaa gaaagtcggg ataccagttc actactggcg gcaatattca
    87361 ttgatttcat aagcgcaaac ccgtttcggg gaagtaagaa taccggacaa ggtggaaaac
    87421 cctgccccat gagatatggg tcaaactggt caccagctcc gaccgccaga catcagtaaa
    87481 agcagaaacg ctctgatttt actgttgtcc tgcagtgagc gtgcgttaac ttcaccgcat
    87541 gagcagtaac atagaaaggg aaacgtttcg cgcgaaacgg cgataagcga gagaatgtaa
    87601 ggagatggcg tgcatcgggc aaactccgta cagagaggag aaaattcgcg caatcatggc
    87661 acctttcgct aaagcgtgca agccaggact ttgcgaccag acaagccatc aacaaggcaa
    87721 aaagttcata ataagaaaat caaacaatac agctaacagg aactcttgtg gtcatcggcc
    87781 cttttatcaa cgctagtgca gtcttactgg gtggcgttct cggcgcactg ctcagccaac
    87841 gcttaccgga acgtatccgc gtctccatga catctatttt tggtctggca tcgctgggga
    87901 ttggtatttt actggttgtg aaatgcgcca accttccagc gatggtttta gctacgctac
    87961 ttggcgctct aattggcgaa atttgtttgc tggagaaagg tgtcaataca gcagtcgcca
    88021 aagcacaaaa tctgtttcgt cactcacgta agaagccagc gcatgaatct tttattcaga
    88081 attatgtcgc gattattgtc ctgttttgcg ccagcggcac cgggatcttc ggggcgatga
    88141 acgaagggat gaccggcgat ccgagtattt taatcgccaa gtcatttctt gatttcttta
    88201 cggcgatgat cttcgcctgc tcgctgggta ttgcggtgtc ggtaattagt atcccattac
    88261 tgatcatcca gttaacgctg gcgtgggctg ccgcgctgat attaccgctg accacaccgt
    88321 cgatgatggc agacttcagc gccgtaggcg gtttattgct gctggcaacc ggattacgca
    88381 tctgtggcat taaaatgttc ccggtggtca acatgcttcc agcactcctt ctggcaatgc
    88441 cgctttccgc cgcctggacc gcctggtttg cctgacaatg cgtgcaatag cggcaaagtg
    88501 atgatagatt gtgcagtctg cagtaaattg aagaaatttg attgacgaga cgaggcgaat
    88561 caggtttaat gcgccccgtt gcccggatag ctcagtcggt agagcagggg attgaaaatc
    88621 cccgtgtcct tggttcgatt ccgagtccgg gcaccactaa ttcttaagaa cccgcccaca
    88681 aggcgggttt ttgcttttgg atctgacaat aaccttcacg aaaaaagttt gcttataaag
    88741 tctgggggaa ttactctcgc cacgttaacg agagtaattt tattgatact aatctcctga
    88801 tactttaccc ccgtccaaac tccagccgct gcacattcac catcccagtc ttctcagcag
    88861 cactggcatc aatttgtgtc acccgcagcg catacttttc atccagcgcg tttaaccagt
    88921 tcagcaggtc attaaacacc accggatcta tccagacctg aatattctcc ccacgctcgg
    88981 ctatccgctt gatgactacc gagtgcgcgg aagcgctgtc actgataacc cgcgatacct
    89041 gcgcaggcgt tgttgtggcg gattttcgcg ccgccataat atccggcgcg gcgctcctca
    89101 gtctggtgtt catcgccacc agttgctgca acattgtctc ctgttgttct atccgttcgc
    89161 tcaacggctg ccagatgagg acgtaatatc cgacgctaaa caggaacacc accgctgcca
    89221 gtaacatgcc cttttcacgc ggagaacgcc ccgccaggtg ttgtgccagc cagtgttcgc
    89281 cacggcttaa ctggcgttca cgccattgct gaaaatagtg aataaattta tcgcgtaaca
    89341 tgttatttcc tccgcaacgt tacgccgccg gaaaccgcat caccctcttt ctgtaacgcg
    89401 tcctgttgca caacataatc ggttgccagt gcactacgca gtttgtcgaa actggcaaag
    89461 ttcgcggccc gtagctggag gtgaagtatc tggcgttttt gatcaaaggt aaaaccacgc
    89521 atttcgatgt cggaaagtga cgctgatttc agggtgctgg ctatcgctga caactcggcg
    89581 agcagccggg tatcgtcggc ctgtgggcga tattttttca gcgccatcgt cacctgagag
    89641 cgtaaattca caatccgctt ctgctccggg aacaacgtta agaactgttc ctccgcctgg
    89701 gtgcggcttt gcgccacctg ttcgctgacg ctccataacg tcacgccccg ctccactgcc
    89761 agcgcaacca gaatcagcaa tatcggcaga atcatcaccc gccagcgcgc ccactgtttt
    89821 cggtagctga cgcgaggctg ccacggccct gtcagcaggt tcccttccgg ttcgccataa
    89881 gtggtaatgg cgggcagagc tgtaacggtc aggcgttcag cgtctgcgcc agcccatgct
    89941 gatagctttt ccggtgcaat gccgactacg gttagcgaaa gcggtaaatc ctgctcattg
    90001 agctgggcgc ggaacatgac cggagccagc gccagcccgg cgctccatcc ccggcattca
    90061 tcgatgcggc agataacccg ttgcgcatcg caagccataa acccacaagg aatggacatc
    90121 cagtccggcg cgacggtagc gcgggtgatg ccgttttcct gcaaccactg cgcaatgttg
    90181 cgcatatgct gttggtgaat cactgctacg gttgccagtt gctggtcgat attcaacggg
    90241 gcgaaatgca gttcatcgat atcctggttc agctcttctt ccagtaaggc gggcagaatg
    90301 gtcggtatct gcttacgggc gacatcaggc agttcaacct gccagacgct gatccattcg
    90361 ccgggaatgt agagtcgaat cgcatcagtt tgcagccatt gctggagctg ttcgttagca
    90421 acgtcagacc agataccgtg ctccacatcg ggtgtacggc gctgccaatg gatgggatca
    90481 gcggcgcaaa gcgggaaaaa aatctcaagg atggaactca ctcactttct cctgtctgat
    90541 gccagagaac cgaaaagtgt tgtgggccca tgcggacaat taacgagttc atcgtcagtt
    90601 caatctcatt cacggtgata tctgaacgca gccagaagta attgctgtcc acgctcagga
    90661 cggtttttag ctgtttttta gtacgctcat cgacgtcagc aagtagcggc tgtgcaagaa
    90721 actgatcgac atcttcccag cccttcgccg gacgttgttg taataacgcc cgcgcctgaa
    90781 cagggcttaa ccacgggtca aacagcgcct caagaatcac actttgcgtg acgtctaaag
    90841 tattgatgtt gatttgctgg cgggtcatcg gcagcgcaca gaccagcggt ttcagttttt
    90901 gataaagccc ggcgtccatt ccctgcacca cgcgcatctc gctgatatcg gccagcggtt
    90961 gattggcggc gtagaaaggc accgagcggg cgagatattc gctgtcttca cggcccagac
    91021 gcgtctgcac gctgcggtct tcatcaataa actcccacag gctttcggct atcagttcgg
    91081 cccgataagc aggcacatcc aggcgcgtga tcagggcaat cagttgttgt accgcgagcg
    91141 gacgcgacgc cgttgtgggc tgagcgaggg cattcaggtt aaagcaggcc tgtgcgtcac
    91201 gcagagtgac ggcgatttgc ccctgcggca gtgggaaaaa acgagggccg gaagcccacg
    91261 gctgttccag atgcacgcgc ttttcatttt tcaggctcag actgagcgcg ctcagcgcca
    91321 ggctttctgc actggcgctg taccacagcg cctgctggta ctcctgctgg ctgcgcgttc
    91381 ttcccagttg ctgctgcatc cgcccggaaa gcgtgatggt taccagcatc ataactgcca
    91441 gcaataccag caccacgacc agtgccattc cgcgttttgg tggtgaggtg atcatgatta
    91501 ttgcggcccg cgtaacaacc agatgcgttc aatctcgccc cattgcggcg aatgcagggt
    91561 catgcgtacc gccacaggga tcgcctgtac tgacgaccag ctctcctgcc agcgcgtgcc
    91621 gtcgtagaac tgcaaacgga gcgaatcggc cggaatcaac ttttgcattg tcggcttcac
    91681 gctgcctgcg gcatcggtca gcggccaggc taaccgttcg agataaccgt catgaatgcg
    91741 gtaaccgacg gtgagcagat tactgcgcgg cagacgcatc aacgggttaa ccacaccgcc
    91801 gcgcacaaaa cgcattcctt cactctcaga cgccagcacg ccagcgccag ccagtaacgc
    91861 tggttcacgc tggccctgat cgcctcttac cggacgcggc atcatttggg tcagatcgtg
    91921 ggtcagaaaa ctcatcgttt gctgcatgag gtttagtttt tgatcgtgtc cggcgacggc
    91981 gctattcacg cgcgtgacgc cgttagtcac ctgctgcgcc atcagtgcca gcgaggcaaa
    92041 aatggcaatt gccaccaaca tttccagtaa cgtgaaacca gcgcgagtcc ttctcactgt
    92101 tggcctccca cggcgctaaa ccaggcgcgt cgtgactgaa tcaccgacga aaagtcttcg
    92161 tgaaggctga cttcaatatc caccgcctgg agcagcgcgt tgcctgtact cagcggtgtg
    92221 gttcgccagt accagcggct tcctgccata tcgctctcgc cctgctgcct gaccgcccgc
    92281 tgctcgcggg tcatcaggta gagcagcgcg gtctggtttt cagccaccca gcccgctacc
    92341 gttttttcct caagaatttg ctgattactc agcgcaccgc tggcaatctg taacaccgcc
    92401 gtggcagcca gcgcaaaaat cgccagcgcg agcatcactt ccagcaaggt aaatccgcgc
    92461 ttcatggcat cctctcatca cattgattga gggataacgc gccatcgtgt gccagcttta
    92521 ccgcccaaca tgcgttttgc gccgccgagt agaagcgcag cgtaaacggc gtggcgggtt
    92581 caaaaggcga aaaacggatc tgcggcgtct tctttttcgc ctctttttgc agctcaagtt
    92641 caatatcgtg cagcgtcagt cgacgacgtt gcagctccag cgcatattcc ttctgccaga
    92701 tatcacttcc gggttgtaac agcatctgca cctgtttcgg caccgtaacc tgtgccgata
    92761 accgggtcga ggaaacgggc gaccactgcc cctgacgacg ctgcataaac tggtagccag
    92821 gcgggtcgat tagcacaccg agtgttttcc cttcgatcac tgccctgtcc ttaaactgcg
    92881 caaagcgagt cagaaaatcc tgcgccgctt ttttcgcggg cgattcagaa tcggtcgcaa
    92941 aagtctgtac cacgcccgca ctggcaaggc cgataagaaa aatcaccagc atgatttcca
    93001 gaagtgtgaa tccgcgttca ggcactgctt actgaaactc ctgcaaattc cagttaccga
    93061 tatctgcgcc agcgccttcc ccgttttcct gaccatccgc ccccagggta taaacatcaa
    93121 acagcccttt ttcacccgga ctgagatact gataatcatt gccccacgga tcctttggca
    93181 gtcgtttaat gtatccacca gtacggtagt tgcgggagtc cgccatattg gctggctgct
    93241 ggatcagcgc ctcaagcccc tgttctgtgg tcggataacg cccgttatcc agtcggtaca
    93301 tatccagtgc gttttccagc gccacgatat cgctgatggc tttttgccga tcggctttct
    93361 ctttgttgcc caacaggtta ggcaccacca gacttgccag gacgccaaga ataacaatca
    93421 ccaccatcac ttccagcagg gtaaaacctg cccgtggttt ttgtgtgcgg gataacgaat
    93481 tcatgtgata actccgtaaa ttacattcca accatattat tcagttgcag catcggctcg
    93541 aggatggcga tgacaataaa cagcaccacg cccgccatca tcaccaccag cgccggttca
    93601 aacagcccta acgccagccc cacctgggta tcaaattccc gttcctggtt gactgcggcc
    93661 tgctcaagca tggtttccag ttcgccgctc tgttcgccgg aggcgatcat gtacagcatc
    93721 atcggcggga acaggcgcaa ctccgccagc gcggcgcgca gactgcttcc ttcgcggacg
    93781 cgatctgccg ccagcagtag ttgttgttcg acatagcgat ttgccgacac ggcggcagca
    93841 gtctgaatac cttccagtag cggaacactg ctggcggtga ggatgcttaa ggtgcgggaa
    93901 aaacgcgccg tattcagccc gcgcgcaaca cgccccgtca caggcaggcg cagcacggtt
    93961 tgatcccagc gcaggcgcat agcaggattt ttaagtagcc gttgccccag caccagaagc
    94021 cccagcaaac ccgccagcca gtaaacgccg ctggcctgta acgcgtcgct catggcaata
    94081 agcgtgcggg ttgaggcggg tagcgcgtgt ccgagatgat caaactgttc gatgattttc
    94141 ggcaccactg ccgtcagcaa aatagtgact acgcccgttg ccaccaccag cagaaccagc
    94201 ggatagagca tggcctgcaa tagacgtgat ttcaggcgct gtcgctgttc ggtgtaatct
    94261 gccaggcgat taagcaccac gtcgagatgc ccggattttt ctccggcagc aaccatcgaa
    94321 caaaacagag aatcaaagac gcggggatgt tcgcgcaggc tgtccgacag ggtgtaacct
    94381 tcctgaatcc ggctgcgcag cgccattccg aggcttttta catgcagttt ttcactttgc
    94441 tcactgaccg cctgtaagca ggtttccagc ggcattgctg cctgtaccag cgttgccagt
    94501 tggcgcgtga acagcgcaag atctgccgcc gccacgcgac gatgtgcgtg ccgccgacgc
    94561 tgcaacatcc cccctgacga agtattcatc cgggcttcaa tatgcacggg gataagctct
    94621 ttaccgcgca acaactggcg ggcatgacgc gcggaatccg cctcaatcat acctttggtt
    94681 ttgcgaccat tacgctccag cgcctgatag taaaacagtg ccattacgcc tccatggtta
    94741 cccgcagaac ttcatcgaga gaggtttctc cggcgagcac tttctcaatg ccgttgctgc
    94801 ggatacccgc agagtgttgt cggacataac gttccagctc cagctccccg gcctgacggt
    94861 ggatcaaatc acgcaatgtg gcatccacca cgatcagctc atggatggca gtccgtccgc
    94921 gaaaaccttt gtgattacag gcgggacagc cctgtggatg gtacagagtg acggtacggg
    94981 cgtcggtaat tcccagcagg cgtttttctt cgtcagtggc tggtgcgggc tggcggcagt
    95041 cgggacacag cgtgcgaacc agtcgctgcg ccatcacgcc cgtcagactg gaagagagca
    95101 ggaaaggctc cacgcccata tcctgcaaac gtgtgatcgc ccccaccgct gtgttggtat
    95161 gcagcgtgga aaggaccagg tgtccggtaa gtgaagcctg gacggcgatt tctgcggttt
    95221 cggtatcgcg gatttcaccg accatcacca catccgggtc ctgacgcaaa atcgcgcgca
    95281 gcccacgggc aaaggtcatg ccgacgcggg tgttaacctg cgtctgaccg atcccttcaa
    95341 tcatgtattc gatgggatct tcaaccgtga gaatgttgcg cgaatggttg ttcagctcct
    95401 gcaatccggc gtacagcgtg gtgcttttgc cggaacccgt cggccccgtc accagaaaga
    95461 tgccgtgcgg tttgtgtaac agctggcgca actgcgcggt cagttgctgg ctaagcccca
    95521 gacgctccag cgtcaggcgg gcctggtttt tgtccagcag tcgcagcacc acgcgctcgc
    95581 cccaggcaga aggcatggtg gagacacgca cgtcaatcgc ccggccgccc agcaacagcg
    95641 caatacgtcc atcctgcggc acgcgctttt cggcaatgtc cagccgcgcc atcaccttga
    95701 tacgcgacac cagcagcgag gccagtttgc gccccggacg cagcatttca tgtaatgtgc
    95761 cgtcaacacg aaaacggatc accagactct tttcaaacgt ctcaatgtgg atatccgaag
    95821 cgccttcttt gattgcctct gccagcatgg cgttgatcag tttgatgatc ggcgcatcgt
    95881 cgtcgctttc cagcagatct tccgtttccg gcagttcttc cgcgagggta aaaaagtcct
    95941 cggcagaacc gagatcttcc atcagttggc gagcctcgga agagtcccgc tgccagaccg
    96001 cattcagccg ctgttcaaat tcggcttcgt cgatttgccg cagcgtaaag ggcgcgttca
    96061 gcccccgctg cagctcctgc aaaacagaga gcgacaacgg atgaacatgg aggatctcca
    96121 gcgacgcttc gcaccatgcc accaggctaa accgacggct gaaactgtag ggcagacgca
    96181 cggtgttagc ggtggtttcc tgtgctacag gcaccattaa cgcgttctcc cggcattaag
    96241 gaacgcacga acttccggcg gtagagcctg attttgcgct ggcagtaccg gctgcgcggt
    96301 gtgcggcatc aggcttaaac cttgctcatc gcgatagatc tgctcggcgc gcatgtagtt
    96361 atatttgcgc tgcgacacgc cgtctgccgc cataccgtca cgcagaatgg tcgggcggat
    96421 aaacaccatc aggttacgtt tttctttttt atccgccgtc gatttaaaca ggttaccaat
    96481 caatgggata tcgcccagca gcggcacttt cgccacgctt tctcccgcct gatcgtccat
    96541 cagaccacca agcacaatca gctcaccatc gttagccagc acggtggttt tcagtttgcg
    96601 ctcaccaaac accacgtcga ggctggtctg tccttccacc ttcgagactt cctgctcaat
    96661 caccatctgt accgcgttac cttcgttaat ctgcggcgtg actttcagca tgatgccgac
    96721 ttttttcctt tctactgtat tgaaaggatt gctgttattg gagccaacgg tagagccggt
    96781 taataccgga acgtcctggc ccaccatgaa gaaggcttcc tggttgtcca gcgtggtgat
    96841 gctcggcgtg gagagcacgt tcgagctgga gtcgttttta accgcctgca ccagcgccat
    96901 ccagtcgcct ttcaccacac caaccgccgt accgctaaag ccggaaagaa gctgggcgag
    96961 cgtggagaga tcgccgttgg tatccggatt aatggtggta gcgccgtttt cactgatcac
    97021 cgtcgagcct ttctgcggtt tcgcctgaga aatggctgcc cccagcgtac cgatagggat
    97081 ctgcgtacca ttagcaaact gcattaatcc ggcatctttc gacgcccact gcacgccgaa
    97141 gttgatattg ctaccttcgg caacttccac gatcaacgcc tcgacgtgca cctgagcacg
    97201 gcgaatatcc agttgttcaa tcacgctttg cagcgactgc atgatgtcct gcggtgcggt
    97261 tacaatcagg gcattactgt gtttgctggc ggcgatggat acaatctcac gcccgctacc
    97321 gaccgtgcct tccgcctctt ctttagccgc cgtgagcgta ccgctgacct gcttcagcac
    97381 atcgaccaga tcttcggctt tgctgtattt gagatagaaa acctggctgt tgccgctgcg
    97441 ttccatttct gagtccagcc gacggatcag gcggcgcatt ttgtcccgcg tggccgggtc
    97501 accactgaca atcacactgt tggtgcgttc gtcggcgaca atttgagatt tcagcgtcgc
    97561 tggctggttc tcgccgctgt ttttcgtcag gctttccagc acgcgggcga tttccgaagc
    97621 cgaggcgtta tccagcggga tcacctcttc ggtgcgatta cccgcgtgat ccacgcgctg
    97681 gatcacttct gtcaggcgct ccacaacgga ggcgcgtccg gtgagcataa tcacgttgga
    97741 gggatcgtaa ttaacaacgt tgcctgagcc tgcgctgtcg atcatctggc gcagaatcgg
    97801 tgccaactcg cgtaccgaca cattacgtac cggcactact ttggtgacca tttcatcgcc
    97861 cgcgtagttg tcgctgcctt caccgaccag cggcagcggc tcgactttcg cagcgctgga
    97921 tttcaccacc ttcagcacgt cgttttccat cggtacgacg gcatacccct gtgcttccag
    97981 caggttaagg aatagctggt aatactggcg ttcattgagc ggggtcatgg tgcgaatact
    98041 cactttcccc tgtacgcccg gccccataat gatggtttta ttaaggttag cgccgacggt
    98101 ttcgatgaac gatttcaggt cggtatcttt aaaattagcg gtgaaagtgg cttcttccgc
    98161 ccagaccggt gaactgcata atgccgctgc cagcaccagc ggcagtaaac gcttttttgt
    98221 tttgaggcca gttgtcttct tacgccagac cgacaacgta atatcacgcc aaaacacgat
    98281 gaatgattct cctggattaa atgcggttag cgcagcgcga tggaaatgtc gtggcgcgca
    98341 cccttgcgta aaaccgtaag ttgaatggaa tccattgaag gtaactgccg catcagagca
    98401 atcattgctc gtggatcagt gaaatcctgc tgatttagcg caatggcgat atcgccttcc
    98461 ttgaaaccgc tggcatcgaa cagagaacga tctgcccccg gcttcactgc ataaccgaca
    98521 attccctcct tacgcacagg cgtaagctgg atatagttaa aaattttctg cggatctttc
    98581 gccagtgcct gacgcacggc agtcgggatc tccactggcg cactgacagc aggttcagca
    98641 acagcttgct ttgcttcgtc actgacagct tttttgttgg tcgcggcaac ggtggaacgc
    98701 tcctcttcag ccaggctcag gcgctctatt tttccctgat agcgcagcat cacatggtcg
    98761 cgattgattt cctcaatcac cgcattgtgc gagccaagcg tttcaccctg caaatagacc
    98821 tgctgtttac cgccttcttc aataaccgcg ccgggtctgg caccaaaggc aatcccgcgc
    98881 agcaccacat taagacgcgt ttctgccaca ggcacaggtt cgggttgttt taccggcgtg
    98941 gcgacgggct gatatttgcc aaaccagttt tgctggctga ttaattgcac gtcattttta
    99001 tcgaacgttt ttgcatccgc acggggcggt ttattcgccg atggggaaac atccgtatat
    99061 tccgcagaaa aggagaaata gcgccagagt gaatgcgcca cttttgcaga aataataagc
    99121 agcatcagcc agaacatccc gcgtacaatt tttcgcagat gctctttgtc tgtattaaaa
    99181 gattgtctct ggttaagagt gtgacgaatt tttgtcagcc attgaatgag ataaattcgt
    99241 gcgtcacgaa aaacaacccg cgccaattta tatctacccg acgttatgct ttgactattc
    99301 cacaggtggt acgatccagt ttccgctgat actggttacc tgtacgtgta tcattaatcg
    99361 ttatgctgta attaattccc tcggtaatca ttaatttcac cgttgggtca gcgcacattt
    99421 gtcgttgata gctggttaaa aaggcgtcag gcgtctgcgt ggtctgagtc cccgcttcgc
    99481 tgataatggt catttttacc gtcgtgccgc tactttgtgc cagcactaag gtatatcccg
    99541 cagatttaat cggcaggttt tggctgatat tttgcgcctg ttttttcgcc agtaaactgg
    99601 cattttcatt atggctggca cagccactta ataatcctgt aacgctcaac aatagcgata
    99661 ttaataccct ccctggcatt tgttttatcg acatggtaaa taatctctaa ggttattaat
    99721 aagagttaaa atgtcacttt gataatgacg ttgttatcat taaaacaatg cctgtagata
    99781 aattgttgct ataccgccca gacttaaaca cggtccaaaa ggcagtgtgg ttgatcctct
    99841 ttttgtaata acggcatata tcaggccgca gcatgatgcg attaaagcaa cattgggtag
    99901 cgacaacggc cccacccaac tacctaacgc agcgaacaat aatacatcgc ccatgcctaa
    99961 tgcttcttta cgcagaacta ctccggctat ccagcgcagg gagtaaaaag cgataaaccc
   100021 caccaggacg ccggtaactg catcttgtag cgtgagcggg ctctgctgcg cccatgccgc
   100081 aatcagtccc gtccacaata cgccctgagt aaaaacatcg ggcagccatt ggtgatcgag
   100141 gtcaatgacg ctcgcggcaa tcagccaggc ggataatatc atcaccgcca gcgcccatcc
   100201 actttccggc cagaccagac tcgccagcaa aaaagcgagt gccgtcaata actccaccag
   100261 cggataacgc ttgctgattt tcgcctgaca atcacggcag cgccctttga gcatcagcca
   100321 ggagagcagc ggaatattgt cacgtatccg gatggtctgc tgacaatgtg ggcagtggga
   100381 acgcggtagc gcaaggctta tttttgactg cgcactcggc atttcaccat gaaactccgc
   100441 catttgttgg cgcagcatga tggggtaacg ccaaatcacc acattcaaaa aactgccgat
   100501 gatcaatcct ccgacggttg ccagtatggg catcgccgcg gggtattgct gaaaaacatc
   100561 aaaaagcatg gttaaaggtt gtttgttgta acttgccgga tgcgggcctg caagtgtatg
   100621 ccatacggct ttcctccagg cccgataagc tggcgcaacc cggtgcgcct tatttcatgc
   100681 cggatgcggc gtgaacgcct tatccggcat acaggattac tcgacagaca tcttatgctc
   100741 ggtaaccttg ttaatggttt ccggtccctg ttccggtttc ggcagcttga gtgacgccag
   100801 cgtgttgtac gccgactggc tcacaccgcc ctcgaagctc atctcgctcg cccccggcag
   100861 ctggtaagca ttcgcacccg gattccattt cttaaagaac tccgaaagat ccgtctgggc
   100921 gacccaggag gcacacagca tcagcgtgtc cgctgcgtta ccgttggatt cagcacagta
   100981 attcttgccg ccaaacttgt cattgctgac ctcatcgccg cgtgctttac gatgcatcaa
   101041 ctggaacagg ttccagcctt tcatcccttc acgctcgctg taaaactctg gcagaggagt
   101101 gccatctgga taccatttct tgatatcaaa gtttttctct gcccattcct tcagctgtgc
   101161 gtacatcagc agacggtcac ccgcaccgcc gcgcgcccat gcctgaccgt tgctttcctc
   101221 cagatattcc ggtgcgacgg taatatcgtc agcgacacgg ttcatcttgc cgagataacg
   101281 atcctgcatg tacagcgcca gcacgttgtt agcgacttca gttgcacccg gtacagtcaa
   101341 cggcgtttct gcggcgttat gaccgacttc atgccagatc agccagtcgt tcagcggcgt
   101401 cgtcggcagc gtggtgctgt tcggcgagaa gctgctgttc attaccggat aacccgaatg
   101461 cgcatcaccg atggagatct gcacatcgtt ggcgaaacga tgtttgtggc ccggcaagtt
   101521 tttataggta aacatccggt gcttaccgtc ttcgctatca cggccgtaga agtcattcat
   101581 cgagctggca aaggtatcca gatcgttagc gaattgctcc agtccgccag tgtaattgct
   101641 ggcattcagg ttcttcttcg gtgtggtata gacgaaagcg tctgattcca gctcacccag
   101701 cggagccggt gagttcagat cgtttttcca tgcgccgtct ttatagaacg gtgcttttac
   101761 cacgccagta aaggtgaagc tggcagattc attggtagag ctattgccct tgatataaat
   101821 caggccaccg taaggcacct tgaacttcac cgtaccgcta gcgtccagag agtacgtttt
   101881 agtcactctt ggcggacggt tcagcgcaac ttcatgcttc tcacgtccgg tcaggtcgtc
   101941 agccagcgcc acggtgacgg tcacaggaac gttcgcattg gacttaatgg tgacctcttt
   102001 ctgagccggt gcccacaggc cagttgactg catgttacct gcaaaccatt tggtcggatt
   102061 cgagtacagg ctgatggttt cagtaacgtt ctgtccctct tccgatactg ctcccggata
   102121 cttctcgaca tcaactttga tgttcagatc ccaccaggaa cggcccagca tcaggcgtgt
   102181 cagcggtttt tccatatagt tgagcgggta gctcgggttc atcatgcccg ctttgctgct
   102241 accgtcaccg tagatcatgt tgttatcgac cagcgatttt ttcagatctg cagaacactt
   102301 ggtgccgcct gcataggcat cattggcgta gcagttcagg aactcggtga acgttttaaa
   102361 gcccagctcg tcatttttgc cttcttcata acgatagctc gtatcgttcc acagccagac
   102421 cgacatgttc tggtacagac gttccagatc gacgcagctc agacgctcac ctttgcgacc
   102481 attggtccgg aagtagagct catgctgata cagacgctga atgttggtgc ctaaatccgc
   102541 agcctgcacc atcgcttttg cagtgtcggc gttaaggctt agttgcgtat actgtggaac
   102601 atacatgcca ccagtaaccg gaacccccgt gccaggacga tattccaggc agttgacctc
   102661 atagtgatat gccggattag tacactcttt cagccccggg aacgcggcga aaattttctc
   102721 cttcgcagcc ttcagagaat cctctgtttt atgatcggcc tcatcaataa aggcataacg
   102781 cgtttcctgt ttgccatcta catcttccag ccagctggca acttccagct tcggtttgtc
   102841 atcaggtttg ttttctacct gatatttcca cttaacttcc cctgtcttac tatcgatggt
   102901 gtacggcagc gcaccatcta cggcaggata acgttcatag acccaaatgc ccgttgcgcg
   102961 ctgctgacga acgcggttcg gatacccttg cggatcgtta tttactaccg acttgttaag
   103021 cgccatcgac aaacctgcgg catcaagcag acgtacaaag ccagatgcgc tctcttcctt
   103081 aagattgctc atcacgtttt ccatgatcag caccgatcca cctttgttca gataggcgat
   103141 cagatcggtc acatcctgct gagtcagctt cggtttgctg gtatctgcac gcagcgggat
   103201 tgcataagga tcgttaccca cctgagtcac atattcaaag ccgttaagga tcagcagcgg
   103261 catttcctgc ggatcgagat cgccatagct acttaaatgc tcaacagaga tgcccgcaaa
   103321 atccggatgg aagtcgaacg cagcgctgtt tcctgtaacc tgaccatgac gtttaaaata
   103381 gacagtatcc aggttggtgc ctacggtcat gctggctttc gcgtccggcg tccatttatc
   103441 gtcggacaga tagcgcagca cgttctccat gaagttcttc atgtcatccg ggtcgctgtt
   103501 gagcgtacac tgcccatctt tattaacgcc cccgttccag ctgtaaccgt tcgggcaacg
   103561 caaaatgctg ttgtagtgtg ggttaccgat aaccatcagt ttgccctcac cgacttgccc
   103621 cagcgaaata aacggcaggt tgaaagtggc ggtatcgcgc gtaacgtttt ccggctcaac
   103681 aagagaaggc gcttccgtaa tgtacgccag ctcgttttta tcccaggcgc gtttttcgcc
   103741 aaacgccagc cagtagtttt tatcattacg cgccatcaga atcgggaagg ccgcgttgga
   103801 gatattcacc accgcctgac cgcgcgcatt acccgtgctg ccatagaagt tagtagagtc
   103861 atggaataca tggaacttgc tgacagattt gtagttcgta tccacgcccc acagcttgtt
   103921 gataacgccc tgaatctggc cgtcattaac attgcgcgtc gtcagcgaga accagcgagc
   103981 ctcgttacaa ccgtcggttt tcgcacaaat cgcggtatcg atctctttgg cctgacccgt
   104041 cttaaactgc tcgataaatt cgtttggcag attaacaact tgctcacctt catccagcgt
   104101 cgcaccgttg gataacgaga gattgataat ctcgttgatc acgttgggat attcggcaaa
   104161 gaccttgcgt acatcatccg gaacaacacg ggtattattt tgcccggtcg tcgaatagcg
   104221 atgaataagc tgatcgatat tcgccccgcg aacttcatca cccagttcag tcagcgcaat
   104281 ggtcgactta ttgccgcgca ctgaacccag ttcaaaggta tcgataccaa aggagatggt
   104341 ttcgccccag ctaaaagaaa attcaccatt ttcccctgtc acgccacggc ctgaattggt
   104401 gtagtagttg acgccagcaa caccatatcc ctggctatcc accaggcgac cttctgagag
   104461 aatgatttcc gaaggttgat actgataaaa ctgttccgcg ttagccgaca cgaaggaggc
   104521 gttcagatcc ggttttgttc ccggagtcgt gacggggact accggtgaag tatgagtgga
   104581 tggcgcttta tcagtcgcgg cattgttttc cacctcttca ttgaccagct ttttgaactc
   104641 ttccggtgcc agatcgattt gcttatacag cgagtcgaaa cgtttactct cgatcaccga
   104701 ggagaactcc aggcacacct gttctgtatt cgccgggcaa ctgttcatgg aggtgaccag
   104761 cgagagcgca ttgcttttct tgttgtcgga acccgccagt tcttgcgcgt cctcaagact
   104821 aaacgacact ttttcaaccg cacgcaggct acgcgcagct tctgactggg tgtcgaaggt
   104881 agcaattgtc gtgttgttcc ctgccacaca ggtgactttg tcgcctggtg taaaggtaaa
   104941 gccatcgctg gattcatcat tacaggtgat atcaccagtt acccgcaggc ttccgcccag
   105001 ggtcagataa cccgttttcg taggaacagg ttctggctcc ggttctggtg ttggctcagg
   105061 atcaggtgtc ggttccggtg taggttctgg gtccggcgtt ggctcaggcg tcggctccgg
   105121 gtttggtgtt ggatcaggtt tcacttccgg caaagaccct gttccagaat ctacaggcgg
   105181 cgtatcggag gaagatccgg agccaccgcc atcacaaccg gctaacaggg ttgcactcaa
   105241 aatagccgct aaaagcgatt tcttatattt aaatttctta ttcattaata acgcaagtga
   105301 caaaacaatg ttaaaaaatt cgtaactggt agaaatattt ttatgcttta tcttctttaa
   105361 taatttcctc cattcttaag aaaacgacat cattgataga aaacaagtga aatttataag
   105421 aataacccct atttgatgtc tggctggcta tttttacgaa atttcaataa acaaaaaatt
   105481 aacaacattt cacaacgcaa ctatataaat tcgttggtag ttttaacgat taagattgca
   105541 aaagcaacag atagaacggt gtttgctcat caagcgaaca taattaatac agacttgttt
   105601 tgcgtgataa aaaaatagat gctctcacgc tcttaattat ttagcaggtt atctgaacac
   105661 aaaacattat tgccgcatgg ataataaagc gagaaataat tttcaattaa taagacagaa
   105721 taatgtaaat gaagccggat gatattaacg atcatccggc attattgatt tacgagacca
   105781 acattccagt aaacacatac gcctgcaaca acgtgataac gccgataacg ctggcaaaaa
   105841 tcagactgtg cttcacggtg tagcggaaca gttcagattc tcggcccacc atgcccgtcg
   105901 cggcgcaagc cacggcgata gattgcgggg agatcatctt gccagttacg ccgccgctgg
   105961 tatttgctgc caccagcaga gtgtcagaga cgttgatttg ctgcgccgtg gtcgattgca
   106021 gtgaaccaaa cagggcgtta gaggaggtgt ccgagccggt aaggaatacg cccagccagc
   106081 cgagaaacgg tgagaagaac gggaacatca cgcctgtacc tgccagtacc agcgccagcg
   106141 tggtggacat gccggaatag ttggtgacga aggcgaacgc cagcaccatg ccaatcgaca
   106201 atatcggcca cttcagacta attagcgttt cggcaaagac gccaatacct ttcttgatgc
   106261 ccacgccgag gatgaagata gagataatcg ccgcaataaa aatagcggtg ccgccagccg
   106321 agagagggtc gaatttaaac accgcatcca ttggcgttgg ttgggcgaca atgggtgccg
   106381 ctttcaacac ttgttgatgc aaatgaggga tctggaaatt aatcaccagt gaataaaacg
   106441 cgccgcccgg agcaaataac gctttaaacg gcttcatggt ccagatggtg accagcaccg
   106501 ttaagattaa aaacggtgac cacgcacgaa tgatttgccc cagactatat tctgaaggca
   106561 cgggaccgcc agaagatggc ttatttacca ccatcgcacc tgcggattgt cccatgctga
   106621 ttgccgtttc ggtatttttc ggccgccaga ctttaaggaa taaagcgagt gcgacgatac
   106681 tcaccagcgc cgaagtaata tccggcagtt ccggaccaat atagttagag gtaaagaact
   106741 gagtgacagc gaagcttccc ccagcaacca gcgccgctgg ccacgtctct ttcacccctt
   106801 tccagccgtc catcattgct accagccaga acggcacaag aaccgacagg aacggtaact
   106861 gacgtcccgc cattgcgcca atgtggaacg gatcgattcc cgttacctga ccggcgacca
   106921 gaatcggcac gcccaacgca ccaaacgcca ccggcgcagt attggcaatc agacacagcc
   106981 ccgccgcgta taacggtttg aagcccaggc ccaccagcag cgcaccggta atcgccaccg
   107041 gcgcaccaaa gccagccgct ccttccagca acgcaccaaa ggagaaacca atcagtaaca
   107101 cctgcaaacg ctgatcgtcg gtgatggaga taaccgagct gcggataata tcgaactgcc
   107161 cgctggcaac ggttaattta tagaggaaca ccgccgcgac aataatccaa gcaataggcc
   107221 ataatccata aataaagcca tagcccgcag cagcaaaagc catatcaatc ggcattttaa
   107281 aggcgaatat tgcaatcagg atagataata taagggttat tgctccagcg acatgtcctt
   107341 tcagacgtaa taccgcgagt gcaacgaaga agaatattat cgggatcagg gcgaccagag
   107401 cggatagccc cagtcctccc attggcatat acatttgggt ccaggtaacc atattgttca
   107461 gtctcttatt atctttatat gcttgatata cttaaggttg taataagcaa gagaggactg
   107521 aactgtaaaa tatagacgtt atactttaca gcaacagtac gccgctaacg caattgctac
   107581 ctctggcata acaagtatat cgggtaaggg tttctgttcc gcacacgcag gcgcagagta
   107641 tcgttaagat gtccatattg ttgttttagg cccgctagta atgcgctacg ggtatttaat
   107701 attgttaaac cctgataatc gctccggtta tttccgggat aaatgtacta ccgcagttac
   107761 tatcatagcc ccgacaataa aacttgccgg ggcttttttg acgctattaa tgactttctt
   107821 tttcgcgtaa acgccaggcg tgtaataacg gttcggtata accgtttggc tgtttcacgc
   107881 cgaggaagat caaatcgctg gcagctttaa aagcacacga gttagcgaaa ttccccgcca
   107941 tcggacgata agccggatcg ccagcgtttt gctgatcaac cactttcgcc atattctcca
   108001 gcgacgcctg cacctgttct ttggtcagaa taccgtgacg taaccagttg gcgatatgct
   108061 ggctggagat acgcagcgtt gcgcggtctt ccatcagcgc cacattgtga atatccggca
   108121 cttttgaaca accaatcccc tgctccaccc agcgcaccac gtaccccaga atcccctgca
   108181 cgttgttatc cagctcttgt tggatctctt gcgccgacca gttagcgttt tcagcaaccg
   108241 gaatagtcag cagatcgtcc agcagcggtt caaattcagc attaaactcg gtctgggcaa
   108301 tgttggcttg cacgctctgt acgttggttt ggtggtagtg cagcgcatgg agcgtagcag
   108361 cggttggtga cggaacccag gctgtgtttg ccccggcacg cagttggtcg cccttctggc
   108421 tgtacatgtc tgccatcagg tccggcattg cccacatgcc tttaccgatt tgcgctttac
   108481 cgcgcagccc acagaacagg ccggaaagca cgttattacg ctcgtaggct ttgatccacg
   108541 gcgtcgattt catctgattt ttacgcagca tcgggccagc ttccatcacc gaatgcattt
   108601 catcgccggt acggtcgagg aaaccggtat tgatgaacgc cacgcggttg cgcgcctgag
   108661 cgatacagct acgcaagttc agcgaggtcc gacgttcttc atccataatg cccattttca
   108721 gggtattcgg tgccataccg agcattgtct caatgcgggt aaacagtttg ttggcgaacg
   108781 ccacttcctg cggaccgtgc attttcggtt tcacaatata gacgctgcca gtgcgcgagt
   108841 ttttctgcac ttttaaatca tagagggcaa tcgcgccagt catgacgcca tcaagaatgc
   108901 cttccgggat ttcattgcct tcgctgtccc aaatcacagg aatggtcatc aaatgaccca
   108961 cgttgcggat aaacagcaac gagcgtccgt gcagagaaat ttcagagcca tcggcggcgg
   109021 tgtactgacg atcatcattc agtttacgca cgatttgacg accgttttta tccattttct
   109081 cttgcagagt cccctgcatc aggcccagca gattgcggta cagcaggatt ttatcttccg
   109141 catcaaccgc cgcgaccgaa tcttcgcagt cgagaatggt actgatggcc gcttcgacga
   109201 taacatcgtt gatgtgcgcc ggatcgtctt tgccaatccg cccgttggca tcaatttgca
   109261 gttcaatatg caggccgtta tttttcagca aaatgcaggt cggcgcagcg gcatcgccac
   109321 ggtaaccgac aaactgcgcc ggggtacgta acgtggtttc tttaccattt ttcaactgga
   109381 tgcgtaattg tttatcgacc accttaaacg ccaccacatc ctgatagctg ccgttttcca
   109441 gcggtagaga ttcatcgagg aaacgccgaa cccaggcgat aacctgctca ccgcgttgcg
   109501 gatcgtagcc gctgaccatc gccccttcct gcgggatgat gtcgctgccg tataacgcat
   109561 cgtacagtga gccccagcga gcgttcgccg cgttcagcgc gtagcgggcg ttcattgccg
   109621 gaaccaccag ctgtggcccc gcctgactgg tgatttcgct gtcaatgccc gtggtttcca
   109681 ccgtcacgcg ctccagttgc ggcaccaggt agcccagttc acgcaggaaa gatttatagg
   109741 ccgctttatc ttttaccggc cccggattgc tgcgatgcca ctcatcaagc gccgcctgaa
   109801 tgcgatcgcg ttctgccagc aactgacgat tttctggtgc caaatcgtga acgatttcat
   109861 caaaattgcg ccagaacgcc gcagcgtcca gccctgttcc cggtaaaact tcttcatcca
   109921 caaaacgttt aaaattggcg tcaatgcgta aacggccctg ggttatggtt tgactcattg
   109981 tttatctcct cgttttcgct tatttcgcca acaccgctgc tgccgctttc gcgacctgcg
   110041 catcctgtgc tccggttaaa ccagaaacgc ccacggcacc aataatttgc ccatcaacaa
   110101 caaccggtac gccaccttcc agcgacgtca gtaacggcgc agtcacgaac gcggtacgtc
   110161 cgttgttcac catctcttca tagcccttag tttcacgacg ccccagcgcg gcggtacgcg
   110221 ctttctcctg ggagatgtaa gccgcaatcg gcgcgcaatc gtccatgcga cttaacgcca
   110281 gcagatgacc gccgtcatcg gcaacagcaa tggaaacaga ccagttattt ttctgcgcct
   110341 cttcctgacc tgcggcaata attgcactcg ccatttgctg gctaagaatg actttagttt
   110401 tcattttttt attccttttc aagggcttgt tctacaattt caatccagtg acgcacagag
   110461 gtacgaccgg cgctcgccag atgcgtctgg caaccaatgt tggcggtgac gatcatttcc
   110521 ggtttgccgc tttccagcgc attcattttg ttatcccgca gctggcgtgc cagatcggga
   110581 tgcgttaacg catatgttcc cgctgaaccg cagcacagat ggctgtcggg aacgtccgtt
   110641 aaggtaaatc caagacgaag caacactttt tccacttcgc cgttcagctt ttgcgcatgt
   110701 tgtagggtac acgggcagtg gaaggccagt tttttatcgc cgcgaactgc cagtttttcc
   110761 agcggttcct cgcgcagaag ctcgactaaa tcgaccgcca gttcactgac ttgacgcgct
   110821 ttatcggcat ataacgcatc gtttttcagc atctgcccgt actctttgac aaacgcgccg
   110881 caaccgctgg cggtttgcaa aattgcctcg gcacctgctt caatcgcggg ccaccaggca
   110941 tcaatattat tgcgcgcccg cgccagccct ttctcctgcg cattaagatg atagtccacc
   111001 gcgccacaac agcctgcttc gttagctgac atgacgctga tccccagacg atccagcact
   111061 cgcgcagttg ccgcgttggt gttgggcgaa agcgtaggct gggcgcagcc ttccagcatt
   111121 aaaacccgac gcttatggcg cagcggcgga cgcggtttag ctttcaccgt ttcggcaggc
   111181 agttttgctc tgacctgttc cggtaaaaac ggtcgcagca ccagccctac ctgcgtcagc
   111241 gcacggaaga cagccggacg cggcactacc tggcgcaatc cttcgcgcag tattcgctcc
   111301 ggcagtgggc gtttcacttt ctgctcgaca atatcacgcc cgatatccag caaattgtga
   111361 tagcgcacac cagaaggaca ggtggtttca caattgcggc aagtgaggca gcgatcaaga
   111421 tgctcctgtg ttttaagcgt gacttcgttg ccttccagca cctgtttaat cagatagatg
   111481 cgcccgcgcg gcccgtccag ttcatcgccc agaagctgat aggttgggca ggttgcggta
   111541 caaaatccgc agtgaacaca ggcgcgcagg atgctgtcgg cttccagcgc gcgcgcgttc
   111601 tgccgcatct cttcagttaa ttgggtttgc atagcctgct cctcaaagtt ccgcgtacat
   111661 gcgaccgggg ttaaacacgc cgcaagggtc gagctgctgt ttaagctgct ggtgatagcg
   111721 gaataaagga gccgatagcg gggcaaagcc accatctccg gcactaaagc gggtcgcatg
   111781 accgccagcg ttgcgggcga tgcgatggat ttgattgtcc tcggctgtcg atttcagcca
   111841 gcgtaacgct ccgccccagt cgatcagttg ctcgccgggt aaatccatca tcggcgcatc
   111901 gctgggtaat gaaatgcgcc ataaggtacc tggtaacgag aagaacggca gttgttgttc
   111961 acgcaattgc tgccagaact gacccgcaac ctcttcgccc cccagcagtt cacgcgccgc
   112021 ttttaccgat ccttcgccgc cctcaaggcg gatccacaac gcattgtcga agtaacataa
   112081 gccactaata ggtagcggct ggagttgcca ctgggcgatt tcgttcatgg cttcttgcag
   112141 gctgatttcc cgacgcaggc tcagggaggc gcgcggtcgc ggtaacactt tcatcgagat
   112201 ttcagtgagc acgccaagac aaccgtagct tccggccatt aaccgtgaga gatcgtatcc
   112261 ggcaacgttt ttcatcactt cgccaccaaa acgcagatgt tttccagcgc cggtaatgat
   112321 gcgcgtgccg aggacaaaat cgcggaccga accgctccac gggcgacgcg gccccgccag
   112381 cccgcaggcg accatcccac cccaggtggc ttcttcacca taatgcggcg gctcgcaggg
   112441 aagcatttgc ccggcgctct ccagcgccgc ttcaatcgcc accagcggcg ttccggcacg
   112501 cgcggttatc accagctcgg tcgggtcgta attaacaatg ccgcgatgac aacgcacatc
   112561 cagcgtttgc ccggtgacag ggcgacctaa aaaggctttg ctattgctgc cctgaatcac
   112621 cagcggcgtt ttatcgctaa ttgcctgatt cacctgctcc agcagcgcct ggctgtaatc
   112681 acactcgcgt agcatcagaa acgctccagt tcagggaaag gtaaatgacc gtgatgcaca
   112741 tgcatggcac caaattcagc acagcggtgt agcgtgggaa tgtttttccc agggttcagc
   112801 aaaccatcgg ggtcaaacgc cgccttgacc gcatggaagg tcgtgatttc atcgctgttg
   112861 aactgggcgc acatttgatt gattttttct cgcccgatgc catgttcccc actgatgctg
   112921 ccgccaactt caacgcagag ttcgaggatc ttcccaccca gctcttccgc gcgggcaaat
   112981 tcaccgggtt cgttggcatc gaaaaggatt aacgggtgca tgttgccatc tccggcatga
   113041 aagacgttgg caacacgtaa atcatattgc tgcgataaac gggcaatgcc ttccagtacg
   113101 ccaggcaggg cgcgacgcgg gatggtgcca tccatgcagt agtaatccgg ggagatacgt
   113161 cctaccgccg ggaacgcatt tttgcgaccg gcccagaaac gtacgcgctc tgcttcgtcc
   113221 tgtgccagac ggacgtcagt cgcgcccgct ttcaacaaga tgtcgttaac ccgctcgcag
   113281 tcttcctgta cgtcagactc cacgccgtcc agctcgcata acaaaattgc ttcggcgtcg
   113341 acgggataac cggcatgaat aaaatcttcc gccgcgcgga tcgacaggtt atccatcatc
   113401 tccagcccgc cggggataat gccattggcg atgatgtcac caactgcaag tccggctttt
   113461 tctaccgagt caaagctggc taacagaacc cgcgccacgg gcggcttcgg cagcagtttt
   113521 accgtcactt cggtggtcac gccgagcata ccttccgatc cggtgaacag agccagcagg
   113581 tcaaaaccag gtgaatccag cgcgtccgat cccagcgtca gcgcctcgcc gtccagcgtt
   113641 tgcacttcaa ttttcagcag gttatgtacg gtcagaccat atttcaggca gtggacgccg
   113701 ccggcatttt ctgccacgtt gccgccaatg gaacaggcga tttgtgagga agggtccggt
   113761 gcgtagtaga gattatgcgg tgcaacggcc tgggagatcg ccaggttacg cacgcctggc
   113821 tgcacgcgcg cgcggcgacc aacggggtta atgtcgagga tctctttaaa gcgcgccatc
   113881 accaacaaca cacctttttc cagcggcagc gcgccaccag aaagcccggt gcctgcacca
   113941 cgggtcacca ccggtacacg caggcgatgg cagacagcaa gaatcgctgt cacctgttcc
   114001 atttgcttag gcagaacaac cagtaatgga cgcgtgcgat acgcgctcaa cccgtcacac
   114061 tcgtaaggaa tgatctcctc atcggtatgc aggatctcaa gtccagggac atgctcacgc
   114121 agtgccatca gtaccgatgt gcggtcgaca tcgggtaaag cgccatcaag acgctcttcg
   114181 tacaagatgc tcatgagtag gcttcgcttt gttgtgttgt gtggcagctg atttttgcgc
   114241 gctgcttctg tgaacagtta ttaagcgggc ttttcgtttt cgtctatctc tttagctacc
   114301 ggtcagacca ttttttttcc agctctgtga ccttgccttg gttaactcaa tgttaaattg
   114361 atgtaacata atcacttacg tgatgtgcgt gttttgcgag ttaagaacag aaaaattggt
   114421 cctacctgtg cacgaggtcc gggaatgaaa gatgaacgtc gccctatttg cgaagtggtt
   114481 gcagagagta tcgaacggtt aattatcgac ggcgtactga aggtcggtca gccacttccc
   114541 tcggaacgtc gactgtgtga aaagctcggc ttctcacgct ccgcactgcg tgaagggctg
   114601 accgtgctgc gcgggcgcgg gattattgag acggcgcagg gtcgcgattc tcgtgtcgca
   114661 cggcttaatc gggtgcagga caccagcccg ctgatccatc tgttcagtac gcagccgcga
   114721 acgctgtacg atctgctcga cgttcgcgca ttactggagg gcgaatcggc aaggctggcg
   114781 gcaacgctgg gaacgcaggc tgattttgtt gtgataaccc gctgttatga aaaaatgctc
   114841 gccgccagtg agaacaacaa agagatttcg ctgatcgaac atgcgcagtt ggatcacgct
   114901 ttccatctcg ccatttgtca ggcttctcac aatcaggtgc tggtgtttac gctgcaatca
   114961 ttgaccgatc tgatgtttaa ttcagtgttt gccagcgtaa ataatctcta ccatcgacca
   115021 cagcaaaaaa agcagatcga tcgccagcat gcgaggatct acaacgcggt gttgcagcgg
   115081 ctgccgcacg tcgcccagcg cgcagcacgc gatcatgtgc ggaccgtgaa aaagaatctc
   115141 cacgatatcg agctggaagg ccaccatttg attcgctcgg cggtgccgct ggagatgaac
   115201 ctgagttagc tggtattaaa tctgcttttc atacaatcgg taacgcttgt acggctccgc
   115261 cccaatgcgt tccagcatgt tattcatgcc tgtattggtt tcgaggatcc atgacatctc
   115321 cagcgcatcg atcttccggc gggcaaacgg atcgcgtaag gcttcaatca ataacagcgc
   115381 aatcaccggg ccgatgcggc tgaactgata ctcgtcgcgc acgcccatca gcggtactcg
   115441 cgcagttcgc acaccgctga ctttcaaacg ccacagcaat tttgcccagc cgaagggaaa
   115501 gagcgatccg ttcagatcgg caatcgcctc gttgatgttc ggcaagccga caataaacgc
   115561 gcagggtgca gaatcaatct cagcgatata gatcatatcg tccggcacca gatatttaag
   115621 ttgatcgccc atggtcgcga attcatgttc ggtaaacggc acaaatcccc agttgtgctg
   115681 ccagccagag ttgaaaatct cacgcaggat ctgcatttct tcggcaaacc gctgacgatt
   115741 gatgcagcga atggtcacct ttttgcgcac ctgatccatc agttttttta gcgccggaga
   115801 gaaagtgaga tcggttcgct gcatccacca cgccagtaaa tcaatgcctt tgtgataacc
   115861 cagttgttca atatgcgcgg cataccacgg tttgccgtgt ggcatcatcg cacagggtgg
   115921 tgtgtcaaaa ccttcaatca gtaatccgct ttcctgattg atattcaggc tgaaaggacc
   115981 gctgatctta cttgcacctt gtgacttcaa ccacgcttcc gctgcgccaa acaacgcggc
   116041 aaaaacctgc ggatcatcaa tggcgtcaat catgccgaaa tgaccggtat cttcaccgta
   116101 acgctcacgg tgcaaggtat ctatttgcgc ggtaatacgc ccaactatct gccccgcttt
   116161 ttttgccacc cacgcctgcc agatgatatg gtccgtcccc ggatttttcg cagacaaatg
   116221 ctcgttgcgt tctatgaata aagggggtat ccagtttgga tcgtcgggat aaagtgatga
   116281 cggaaaagcg ataaatgcct taaggtcatt tttattaatt actttttcaa ttttaatcat
   116341 cagcagatcg cattccatat ctctgtggat aacaaataat taacggtgaa aaacaggttg
   116401 caacagca
//
LOCUS       DAPOAV010000004       105633 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.004, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000004 DAPOAV010000000
VERSION     DAPOAV010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 105633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 105633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..105633
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.004"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            142..3876
                     /gene="yfaL"
                     /locus_tag="RN951_000356"
     CDS             142..3876
                     /gene="yfaL"
                     /locus_tag="RN951_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIDA-I family autotransporter adhesin YfaL/EhaC"
                     /protein_id="HDX2525420.1"
                     /translation="MRIIFLRKEYLSLLPSMIASLFSANGFAAAIDLCKGYDIKASCH
                     ASRQSLSGITQDWSVADGQWLVFSDMTNNASGGAVFLQQGAEFSLLPENETGMTLFAN
                     NTVTGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAVDLRVTNA
                     MFRNNIANDGKGGAIYTINNDVYLSDVIFDNNQAYTSTSYSDGDGGAIDVTDNNSDSK
                     HPSGYTIINNTAFTNNTAEGYGGAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSA
                     AGYGDGPSTAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVDSIAGTGLITKTGSG
                     DLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDKYQN
                     QAELNVGSTQQTFVHSLTGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSY
                     VLSGAQSMALTGDIVVDDGAVLSLEGDAADLAALQDDPQSIVLNGGVLDLSDFSTWQS
                     GTSYNDGLEVSGSSGTVIGSQDVVDLAGGDNLHIGGDGKDGVYVVVDASDGQVSLANN
                     NSYLGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQESVMEITANVDTRSTTTEHG
                     RDIEMRADGEVAVDAGVDTQWGALMADSSGQHQDEGSTFTKTGAGTLELTASGTTQSA
                     VRVEEGTLKGDVADIFPYASSLWVGDGATFVTGADQDIQSIDATSSGTIDISDGTVLR
                     LTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSDVTVNGNLTNT
                     SGAVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVN
                     SITGIGEPTSTGIKVVDFAADPTQFQNNAKFSLAGSGYVNMGAYDYTLVEDNNDWYLR
                     SQEVTPPLPPDPDPDPTPDPDPTPDPIPAYQPVLNAKVGGYLNNLRAANQAFMMERRD
                     HAGGNGQTLNLRVIGGRYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGDDGEWMLGAVG
                     GYSDNQGESRSNMTGTRADNQNHGYAVGLTSSWYQHGNQKQGAWLDSWLQYAWFNNDV
                     SEQDDGTDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQDDFTAANHARVS
                     QSQGDDIQTRLGLHSEWRTAVGVTPTLDLNYYHDPHATEIEEDGSTISDDAVKRRGEI
                     KVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW"
     gene            complement(3937..4659)
                     /locus_tag="RN951_000357"
     CDS             complement(3937..4659)
                     /locus_tag="RN951_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-demethylubiquinone
                     3-O-methyltransferase/2-octaprenyl-6-hydroxy phenol
                     methylase"
                     /protein_id="HDX2525421.1"
                     /translation="MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLR
                     LGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESG
                     IQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTL
                     NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNP
                     ITNTFKLGPGVDVNYMLHTQNK"
     gene            4806..7433
                     /gene="gyrA"
                     /locus_tag="RN951_000358"
     CDS             4806..7433
                     /gene="gyrA"
                     /locus_tag="RN951_000358"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit A"
                     /protein_id="HDX2525422.1"
                     /translation="MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPV
                     HRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDLAVYNTIVRMAQPFSLRYML
                     VDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP
                     TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFP
                     TAAIINGRRGIEEAYRTGCGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEK
                     IAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINM
                     VALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDP
                     IIELIRHAPTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYL
                     TEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELEL
                     VREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKG
                     KSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLP
                     LEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDEL
                     IGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRG
                     DGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMI
                     TDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAA
                     EGDDEIAPEVDVDDEPEEE"
     gene            7582..9270
                     /locus_tag="RN951_000359"
     CDS             7582..9270
                     /locus_tag="RN951_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416733.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2138 domain-containing protein"
                     /protein_id="HDX2525423.1"
                     /translation="MSGEKKAKGWRFYGLVGFGAIALLSAGVWALQYAGSGPEKTLSP
                     LVVHNNLQIDLNEPDLFLDSDSLSQLPKDLLTIPFLHDVLSEDFVFYYQNHADRLGIE
                     GSIRRIVYEHDLTLKDKLFSSLLDQPAQAALWHDKQGHLSHYMVLIQRSGLSKLLEPL
                     LFAATSDSQLSKTEISSIKINSETVPVYQLRYNGNNALMFATYQNKMLVFSSTDMLFK
                     DDQQDTEATAIAGDLLSGKKRWQASFGLEERAAEKTPVRQRIVVSARLLGFGYQRLMP
                     SFAGVRFEMGNDGWHSFVALNDESASVDTSFDFTPVWNSMPAGASFCVVVPYSHGIAE
                     EMLSHISQENDKLNGALDGAAGLCWYADSKLQTPLFVGQFDGTAEQAQLPGKLFTQNI
                     GAHESKAPEGVLPISQTQQGEAQIWRREVSSRYGQYPKAQAAQPDQLMSDYFFRVSLA
                     MQNKTLLFSLDDTLVNNALQTLNKNRPAMVDVIPTDGIVPLYINPQGVAKLLRNETLT
                     SLPKNLEPVFYNAAQTLLMPKLDALSQQPRYVMKLAQMEPGAAWQWLPITWQPL"
     gene            9267..9890
                     /locus_tag="RN951_000360"
     CDS             9267..9890
                     /locus_tag="RN951_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311139.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1175 domain-containing protein"
                     /protein_id="HDX2525424.1"
                     /translation="MRHGLLALICWLCCVVAHSEMLNVEQSGLFRAWFVRIAQEQLRQ
                     GPSPRWYQQDCAGLVRFAANETLKVHDSKWLKSNGFSSQYLPPEMTLTPGQRQLAQNW
                     NQGNGKTGPYVTAINLIQYNSQFIGQDINQALPGDMIFFDQGDAQHLMVWMGRYVIYH
                     TGSATKTDNGMRAVSLQQLMTWKDTRWIPNDSNPNFIGIYRLNFLAR"
     gene            9824..14428
                     /locus_tag="RN951_000361"
     CDS             9824..14428
                     /locus_tag="RN951_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014640177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-2-macroglobulin family protein"
                     /protein_id="HDX2525425.1"
                     /translation="MDTQRFQSQFHWHLSFKFSGAIAACLSLSLVGTGLANADDSLPS
                     SNYAPPAGGTFFLLADSSFSSSEEAKVRLEAPGRDYRRYQMEEYGGVDVRLYRIPDPM
                     AFLRQQKNLHRIVVQPQYLGDGLNNTLTWLWDNWYGKSRRVMQRTFSSQSRQNVTQAL
                     PELHLGNAIIKPSRYVQNNQFSPLKKYPLVEQFRYPLWQAKPVEPQQGVKLEGASSNF
                     ISPQPGNIYIPLGQQEPGLYLVEAMVGGYRATTVVFVSDTVALSKVSGNELLVWTAGK
                     KQGEAKPGSEILWTDGLGVMTRGVTDDSGTLQLQHISPERSYILGKDAEGGVFVSENF
                     FYESEIYNTRLYIFTDRPLYRAGDRVDVKVMGREFHDPLHSSPIVSAPAKLSVLDANG
                     SLLQIVNVTLDARNGGQGSFRLPENAVAGGYELRLAYRNQVYSSSFRVANYIKPHFEI
                     GLALDKKEFKTGEAVSGKLQLLYPDGEPVKDARVQLSLRAQQLSMVGNDLRYAGRFPV
                     SLEGSETVSDASGHVALNLPAADKPSRYLLTVSASDGAAYRVTTTKEILIERGLAHYS
                     LSTAAQYSNSGESVVFRYAALESSKQVPVTYEWLRLEDRTSHSGELPSGGKSFTVNFA
                     KPGNYNLTLRDKDGLILAGLSYAVSGKGSTAHTGTVDIVADKTLYQPGETAKMLITFP
                     EPIDEALLTLERDRVEQQSLLSHPANWLTLQRLNDTQYEARVPVSNSFAPNITFSVLY
                     TRNGQYSFQNAGIKVAVPQLDIRVKTDKTHYQPGELVNVELTSSLKGKPVSAQLTVGV
                     VDEMIYALQPEIAPNIGKFFYPLGRNNVRTSSSLSFISYDQALSSEPVAPGATNRSER
                     RVKMLERPRREEVDTAAWMPSLTTDKQGKAYFTFLMPDSLTRWRITARGMNGGGLVGQ
                     GRAYLRSEKNLYMKWSMPTVYRVGDKPAAGLFIFSQQDNEPVALVTKFAGAEMRQALT
                     LHKGANYISLAQNIQQSGLLSAELQQNGQVQDSISTKLSFVDNSWPVEQQKNVMLGGG
                     ENALMLPEQASNIRLQSSETPQEIFRNNLDALVDGPWGGVINTGSRLIPLSLAWRSLA
                     DHQSAAANDIRQMIQDNRLRLMQLAGPGARFTWWGEDGNGDAFLTAWAWYADWQASQA
                     IGVTQQPEYWQHMLDSYAEQADNMPLLHRALVLAWAQEMNLPCKTLLKGLDEAIARRG
                     TKDEDFSEEDIRDINDSLILDTPESPLADAVANVLTMTLLKKAQLKSTVMPQVQQYAW
                     DKAANSNQPLAHTVVLLNSGGDATQTAAILSGLTAEQSTIERALAMNWLAKYMATMPP
                     VVLPAPAGAWAKHKLTGGGEDWRWVGQGVPDILSFGDELSPQNVQVRWREPAKMAQQS
                     NIPVTVERQLYRLIPGEEEMSFILQPVTSNEIDSDALYLDEITLTSEQDAVLRYGQVE
                     VPLPPGADVERTTWGISVNKPNAAKQQGQLLEKARNEMGELAYMVPVKELTGTVTFRH
                     LLRFSQKGQFVLPPARYVRSYAPAQQSVAAGSEWTGMQVK"
     gene            14429..16078
                     /locus_tag="RN951_000362"
     CDS             14429..16078
                     /locus_tag="RN951_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfaQ family protein"
                     /protein_id="HDX2525426.1"
                     /translation="MNWRRIVWLLALVTLPTLAEETPLQLVLRGAQHDQLYQLSSSGV
                     TKVSALPDSLTTPLGSLWKLYVYAWLEDTHQPEQPYQCRGNSPEEVYCCQAGESITRD
                     TALVRSCGLYFAPQRLHIGADVWGQYWQQRQAPAWLASLTTLKPETSVTVKSLLDSLA
                     TLPAQNKAQEVLLDVVLDEAKIGVASMLGSRVRVKTWSWFADDKQEIRQGGFAGWLTD
                     GTPLWVTGSGTSKTVLTRYATVLNRVLPVPTQVASGQCVEVELFARYPLKKITAEKST
                     TAVKPGVLNGRYRVTFTNGNHITFVSHGETTLLSEKGKLKLQSHLDREEYVARVLDRE
                     AKSTPPEAAKAMTVAIRTFLQQNANQEGDCLTIPDSSATQRVSASPATTGARTMTAWT
                     QDLIYAGDPVHYHGSRATEGTLSWRQATAQAGQGERYDQILAFAYPDNSLSRWGAPRS
                     TCQLLPKAKAWLAKKMPQWRRILQGETGYNEPDVFAVCRLVSGFPYTDRQQKRLFIRN
                     FFTLQDRLDLTHEYLHLAFDGYPTGLDENYIETLTRQLLMD"
     gene            16083..16859
                     /locus_tag="RN951_000363"
     CDS             16083..16859
                     /locus_tag="RN951_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfaP family protein"
                     /protein_id="HDX2525427.1"
                     /translation="MRKIFLPLLLVALSPVAHSEGVQEVEIDAPLSGWHPAEGEDASF
                     SQSINYPASSVNMADDQNISAQIRGKIKNYAAAGKVQQGRLVVNGASMPQRVESDGSF
                     ARPYIFTEGSNSVQVISPDGQSRQKMQFYSMPGTGTIRARLRLVLSWDTDNTDLDLHV
                     VTPDGEHAWYGNTVLKNSGALDMDVTTGYGPEIFAMPAPVHGRYQVYINYYGGRSETE
                     LTTAQLTLITDEGSVNEKQETFIVPMRNAGELTLVKSFDW"
     gene            17134..19983
                     /gene="rcsC"
                     /locus_tag="RN951_000364"
     CDS             17134..19983
                     /gene="rcsC"
                     /locus_tag="RN951_000364"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416722.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RcsC"
                     /protein_id="HDX2525428.1"
                     /translation="MKYLASFRTTLKASRYMFRALALVLWLLIAFSSVFYIVNALHQR
                     ESEIRQEFNLSSDQAQRFIQRTSDVMKELKYIAENRLSAENGVLSPRGRETQADVPAF
                     EPLFADSDCSAMSNTWRGSLESLAWFMRYWRDNFSAAYDLNRVFLIGSDNLCMANFGL
                     RDMPVERDTALKALHERINKYRNAPQDDSGSNLYWISEGPRPGVGYFYALTPVYLANR
                     LQALLGVEQTIRMENFFLPGTLPMGVTILDENGHTLISLTGPESKIKGDPRWMQERSW
                     FGYTEGFRELVLKKNLPPSSLSIVYSVPVDKVLERIRMLILNAILLNVLAGAALFTLA
                     RMYERRIFIPAESDALRLEEHEQFNRKIVASAPVGICILRTADGVNILSNELAHTYLN
                     MLTHEDRQRLTQIICGQQVNFVDVLTSNNTNLQISFVHSRYRNENVAICVLVDVSSRV
                     KMEESLQEMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPKGVDRLV
                     TAMNNSSSLLLKIISDILDFSKIESEQLKIEPREFSPREVMNHITANYLPLVVRKQLG
                     LYCFIEPDVPVALNGDPMRLQQVISNLLSNAIKFTDTGCIVLHVRADGDYLSIRVRDT
                     GVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLISMMDGDISVDSEPGMGS
                     QFTVRIPLYGAQYPQKKGVEGLSGKRCWLAVRNASLCQFLETSLQRSGIVVTTYEGQE
                     PTPEDVLITDEVVSKKWQGRAVVTFCRRHIGIPLEKAPGEWVHSVAAPHELPALLARI
                     YLIEMESDDPANALPSTDKAVSDNDDMMILVVDDHPINRRLLADQLGSLGYQCKTAND
                     GVDALNVLSKNHIDIVLSDVNMPNMDGYRLTQRIRQLGLTLPVIGVTANALAEEKQRC
                     LESGMDSCLSKPVTLDVIKQTLTVYAERVRKSRES"
     gene            complement(20183..20833)
                     /gene="rcsB"
                     /locus_tag="RN951_000365"
     CDS             complement(20183..20833)
                     /gene="rcsB"
                     /locus_tag="RN951_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RcsB"
                     /protein_id="HDX2525429.1"
                     /translation="MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINN
                     LPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLD
                     IEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLR
                     LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD"
     gene            complement(20850..23522)
                     /gene="rcsD"
                     /locus_tag="RN951_000366"
     CDS             complement(20850..23522)
                     /gene="rcsD"
                     /locus_tag="RN951_000366"
                     /EC_number="2.7.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase RcsD"
                     /protein_id="HDX2525430.1"
                     /translation="MRQKETTATTRFSLLPGSITRFFLLLIIVLLVTMGVMVQSAVNA
                     WLKDKSYQIVDITHAIQKRVDNWRYVTWQIYDNIAATTSPSSGEGLQETRLKQDVYYL
                     EKPRRKTEALIFGSHDNSTLEMTQRMSTYLDTLWGAENVPWSMYYLNGQDNSLVLIST
                     LPLKDLTSGFKESTVSDIVDSRRAEMLQQANALDERESFSNMRRLAWQNGHYFTLRTT
                     FNQPGHLATVVAFDLPINDLIPPGMPLDSFRLEPDATATGNNDNEKEGTDSVSIHFNS
                     TKIEISSALNSTDMRLVWQVPYGTLLLDTLQNILLPLLLNIGLLALALFGYTTFRHFS
                     SRSTESLPSTAVNNELRILRAINEEIVSLLPLGLLVHDQESNRTVISNKIADHLLPHL
                     NLQNITTMAEQHQGIIQATINNELYEIRMFRSQVAPRTQIFIIRDQDREVLVNKKLKQ
                     AQRLYEKNQQGRMTFMKNIGDALKEPAQSLAESAAKLNAPESKQLANQADVLVRLVDE
                     IQLANMLADDSWKSETVLFSVQDLIDEVVPSVLPAIKRKGLQLLINNHLKAHDMRRGD
                     RDALRRILLLLMQYAVTSTQLGKITLEVDQDESSEDRLTFRILDTGEGVSIHEMDNLH
                     FPFINQTQNDRYGKADPLAFWLSDQLARKLGGHLNIKTRDGLGTRYSVHIKMLAADPE
                     VEEEEERLLDDVCVMVDVTSAEIRNIVTRQLENWGATCITPDERLISQDYDIFLTDNP
                     SNLTASGLLLSDDESGVREIGPGQLCVNFNMSNAMQEAVLQLIEVQLAQEEVTESPLG
                     GDENAQLHASGYYALFVDTVPDDVKRLYTEAATSDFAALAQTAHRLKGVFAMLNLVPG
                     KQLCETLEHLIREKDVPGIEKYISDIDSYVKSLL"
     gene            24261..25352
                     /gene="ompC"
                     /locus_tag="RN951_000367"
     CDS             24261..25352
                     /gene="ompC"
                     /locus_tag="RN951_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpC"
                     /protein_id="HDX2525431.1"
                     /translation="MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYF
                     SDNKDVDGDQTYMRLGFKGETQVTDQLTGYGQWEYQIQGNSAENENNSWTRVAFAGLK
                     FQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGL
                     VDGLNFAVQYQGKNGSVSGEGMTNNGREALRQNGDGVGGSITYDYEGFGIGAAVSSSK
                     RTDDQNSPLYIGNGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNF
                     EAVAQYQFDFGLRPSLAYLQSKGKNLGRGYDDEDILKYVDVGATYYFNKNMSTYVDYK
                     INLLDDNQFTRDAGINTDNIVALGLVYQF"
     gene            25464..26519
                     /gene="apbE"
                     /locus_tag="RN951_000368"
     CDS             25464..26519
                     /gene="apbE"
                     /locus_tag="RN951_000368"
                     /EC_number="2.7.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase ApbE"
                     /protein_id="HDX2525432.1"
                     /translation="MEISFTRVALLAAALFFVGCDQKPQTAKTHATEVTVLEGKTMGT
                     FWRASIPGIDAKRSAELKEKIQTQLDADDQLLSTYKKDSALMRFNDSQSLSPWPVSEA
                     MADIVTTSLRIGARTDGAMDITVGPLVNLWGFGPEQQPVQIPSQEQIDAMKAKTGLQH
                     LTVINQSHQQYLQKDLPDLYVDLSTVGEGYAADHLARLMEQEGISRYLVSVGGALNSR
                     GMNGEGLPWRVAIQKPTDKENAVQAVVDINGHGISTSGSYRNYYELDGKRLSHVIDPQ
                     TGRPIEHNLVSVTVIAPTALEADAWDTGLMVLGPEKAKEVVRREGLAVYMITKEGDSF
                     KTWMSPQFKSFLVSEKN"
     gene            26593..27657
                     /gene="ada"
                     /locus_tag="RN951_000369"
     CDS             26593..27657
                     /gene="ada"
                     /locus_tag="RN951_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-binding transcriptional
                     regulator/O6-methylguanine-DNA methyltransferase Ada"
                     /protein_id="HDX2525433.1"
                     /translation="MKNATCLTDDQRWQSVLARDPNADSEFVFAVRTTGIFCRPSCRA
                     RHALRENVSFYANACEALAAGFRPCKRCQPDKANAQQHRLDKITHACRLLEQETPVTL
                     EALADQVAMSPFHLHRLFKATTGMTPKAWQQAWRARRLRESLAKGESVTTSILNAGFP
                     DSSSYYRKADETLGMTAKQFRHGGENLAVRYALADCALGRCLVAESERGICAILLGDD
                     DATLISELQQMFPAADNAPADLMFQQHVREVIASLNQRDTPLTLPLDIRGTAFQQQVW
                     QALRTIPCGETVSYQQLANAIGKPKAVRAVASACAANKLAIIIPCHRVVRGDGTLSGY
                     RWGVSRKAQLLRREAENEER"
     gene            27657..28307
                     /gene="alkB"
                     /locus_tag="RN951_000370"
     CDS             27657..28307
                     /gene="alkB"
                     /locus_tag="RN951_000370"
                     /EC_number="1.14.11.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA oxidative demethylase AlkB"
                     /protein_id="HDX2525434.1"
                     /translation="MLDLFADAEPWQEPLAAGAVILHRFAFNAAEQLIRDINNVASQS
                     PFRQMVTPGGYTMSVAMTNCGHLGWTSHRQGYLYSPIDPQTNKPWPAMPQSFHNLCQR
                     AATAAGYPDFQPDACLINRYAPGAKLSLHQDKDEPDLRAPIVSVSLGLPAIFQFGGLK
                     RNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTTDCRYNLTFRQAGKKE"
     gene            28383..30026
                     /gene="yojI"
                     /locus_tag="RN951_000371"
     CDS             28383..30026
                     /gene="yojI"
                     /locus_tag="RN951_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin J25 efflux ABC transporter YojI"
                     /protein_id="HDX2525435.1"
                     /translation="MELLVLVWRQYRWPFISVMALSLASAALGIGLIAFINQRLIETA
                     DTSLLVLPEFLGLLLLLMAVTLGSQLALTTLGHHFVYRLRSEFIKRILDTHVERIEQL
                     GSASLLAGLTSDVRNITIAFVRLPELVQGIILTIGSAAYLWMLSGKMLLVTAIWMAIT
                     IWGGFVLVARVYKHMATLRETEDKLYTDFQTVLEGRKELTLNRERAEYVFNNLYIPDA
                     QEYRHHIIRADTFHLSAVNWSNIMMLGAIGLVFWMANSLGWADTNVAATYSLTLLFLR
                     TPLLSAVGALPTLLTAQVAFNKLNKFALAPFKAEFPRPQAFPNWQTLELRNVTFSYQD
                     NAFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVSGEQP
                     EDYRKLFSAVFTDVWLFDQLLGPEGKPANPQLVEKWLAQLKMAHKLELSNGRIVNLKL
                     SKGQKKRVALLLALAEERDIILLDEWAADQDPHFRREFYQVLLPLMQEMGKTIFAISH
                     DDHYFIHADRLLEMRNGQLSELTGEERDAASRDAVARTA"
     gene            30244..31890
                     /gene="mqo"
                     /locus_tag="RN951_000372"
     CDS             30244..31890
                     /gene="mqo"
                     /locus_tag="RN951_000372"
                     /EC_number="1.1.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase (quinone)"
                     /protein_id="HDX2525436.1"
                     /translation="MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSA
                     TLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISI
                     EKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAAL
                     QQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIAS
                     LQKKSNFSLQLSSEVRALKRNDDNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLL
                     QESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLD
                     GKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVML
                     SEEDRFEALKEYYPQAKKEDWRLWQAGQRVQIIKRDAEKGGVLRLGTEVVSDQQGTIA
                     ALLGASPGASTAAPIMLDLLEKVFGDRVSSPQWQATLKAIVPSYGRKLNGDVAATERE
                     LQYTSEVLGLKYDKPQAADSTPKPQLKPQPVQKEVADIAL"
     gene            complement(32039..32527)
                     /gene="eco"
                     /locus_tag="RN951_000373"
     CDS             complement(32039..32527)
                     /gene="eco"
                     /locus_tag="RN951_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease inhibitor ecotin"
                     /protein_id="HDX2525437.1"
                     /translation="MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQV
                     IQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLESKTLEGWGYDYYVFDKVSSPVS
                     TMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAV
                     VR"
     gene            complement(32662..32826)
                     /locus_tag="RN951_000374"
     CDS             complement(32662..32826)
                     /locus_tag="RN951_000374"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2525438.1"
                     /translation="MHTPIGVKPVAGSKEWREAWQKRAFAHISNGYKHIYIAINSPEI
                     FLLVCSLIRI"
     gene            32935..33429
                     /gene="napF"
                     /locus_tag="RN951_000375"
     CDS             32935..33429
                     /gene="napF"
                     /locus_tag="RN951_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapF"
                     /protein_id="HDX2525439.1"
                     /translation="MKIDASRRGILTGRWRKASNGIRPPWSGDESHFLTHCTRCDACI
                     NACENNILQRGAGGYPSVNFKNNECSFCYACAQACPESLFSPRHTRAWDLQFTIGDAC
                     LAYQSVECRRCQDSCEPMAIIFRPTLSGIYQPQLNSQLCNGCGACAASCPVSAITAEY
                     LHAH"
     gene            33419..33682
                     /gene="napD"
                     /locus_tag="RN951_000376"
     CDS             33419..33682
                     /gene="napD"
                     /locus_tag="RN951_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone NapD"
                     /protein_id="HDX2525440.1"
                     /translation="MHTNWQVCSLVVQAKSERISDISTQLNAFPGCEVAVSDAPSGQL
                     IVVVEAEDSETLIQTIESVRNVEGVLAVSLVYHQQEEQGEETP"
     gene            33679..36165
                     /gene="napA"
                     /locus_tag="RN951_000377"
     CDS             33679..36165
                     /gene="napA"
                     /locus_tag="RN951_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic nitrate reductase subunit alpha"
                     /protein_id="HDX2525441.1"
                     /translation="MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKA
                     PCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPLL
                     RMKNGKYDKEGEFTPITWDQAFDVMEEKFKTALKEKGPESIGMFGSGQWTIWEGYAAS
                     KLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGANMAE
                     MHPILWSRITNRRLSNQNVTVAVLSTYQHRSFELADNGIIFTPQSDLVILNYIANYII
                     QNNAINQDFFSKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFEDYKAFVA
                     EYTLEKTAEMTGVPKDQLEQLAQLYADPNKKVISYWTMGFNQHTRGVWANNLVYNLHL
                     LTGKISQPGCGPFSLTGQPSACGTAREVGTFAHRLPADMVVTNEKHRDICEKKWNIPS
                     GTIPAKIGLHAVAQDRALKDGKLNVYWTMCTNNMQAGPNINEERMPGWRDPRNFIIVS
                     DPYPTVSALAADLILPTAMWVEKEGAYGNAERRTQFWRQQVQAPGEAKSDLWQLVQFS
                     RRFKTEEVWPEELLAKKPELRGKTLYEVLYATPEVSKFPVSELAEDQLNDESRELGFY
                     LQKGLFEEYAWFGRGHGHDLAPFDDYHKARGLRWPVVNGKETQWRYSEGNDPYVKAGE
                     GYKFYGKPDGKAVIFALPFEPAAEAPDEEYDLWLSTGRVLEHWHTGSMTRRVPELHRA
                     FPEAVLFIHPLDAKARDLRRGDKVKVVSRRGEVISIVETRGRNRPPQGLVYMPFFDAA
                     QLVNKLTLDATDPLSKETDFKKCAVKLEKV"
     gene            36172..36867
                     /gene="napG"
                     /locus_tag="RN951_000378"
     CDS             36172..36867
                     /gene="napG"
                     /locus_tag="RN951_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapG"
                     /protein_id="HDX2525442.1"
                     /translation="MSRSAKPQNGRRRFLRDVVRTAGGLAAVGVALGLQQQTARASGV
                     RLRPPGAINENAFASACVRCGQCVQACPYDTLKLATLASGLSAGTPYFVARDIPCEMC
                     EDIPCAKVCPSGALDREIESIDDARMGLAVLVDQENCLNFQGLRCDVCYRECPKIDEA
                     ITLELERNTRTGKHARFLPTVHSDACTGCGKCEKVCVLEQPAIKVLPLSLAKGELGHH
                     YRFGWLEGNNGKS"
     gene            36854..37717
                     /gene="napH"
                     /locus_tag="RN951_000379"
     CDS             36854..37717
                     /gene="napH"
                     /locus_tag="RN951_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinol dehydrogenase ferredoxin subunit NapH"
                     /protein_id="HDX2525443.1"
                     /translation="MANRKRDAGREALEKKGWWRSHRWLVLRRLCQFFVLGMFLSGPW
                     FGVWILHGNYSSSLLFDTVPLTDPLMTLQSLASGHLPATVALTGAVIITVLYALAGKR
                     LFCSWVCPLNPITDLANWLRRRFDLNQSATIPRHIRYVLLVVILLGSALTGTLIWEWI
                     NPVSLMGRSLVMGFGSGALLILALFLFDLLVVEHGWCGHICPVGALYGVLGSKGVITV
                     AATDRQKCNRCMDCFHVCPEPHVLRAPVLDEQSPVQVTSRDCMTCGRCVDVCSEDVFT
                     ITTRWSSGAKS"
     gene            37714..38163
                     /gene="napB"
                     /locus_tag="RN951_000380"
     CDS             37714..38163
                     /gene="napB"
                     /locus_tag="RN951_000380"
                     /EC_number="1.9.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311119.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase cytochrome c-type subunit"
                     /protein_id="HDX2525444.1"
                     /translation="MKSHDLKKALCQWTAMLALVVSGAVWAANGVDFSQSPEVSGTQE
                     GAIRMPKEQERMPLNYVNQPPMIPHSVEGYQVTTNTNRCLQCHGVESYRTTGAPRISP
                     THFMDSDGKVGAEVAPRRYFCLQCHVPQADTAPIVGNTFTPSKGYGK"
     gene            38173..38775
                     /gene="napC"
                     /locus_tag="RN951_000381"
     CDS             38173..38775
                     /gene="napC"
                     /locus_tag="RN951_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type protein NapC"
                     /protein_id="HDX2525445.1"
                     /translation="MGNSDRKPGLIKRLWKWWRTPSRLALGTLLLIGFVGGIVFWGGF
                     NTGMEKANTEEFCISCHEMRNTVYQEYMDSVHYNNRSGVRATCPDCHVPHEFVPKMIR
                     KLKASKELYGKIFGVIDTPQKFEAHRLTMAQNEWRRMKDNNSQECRNCHNFEYMDTTA
                     QKSVAAKMHDQAVKDGQTCIDCHKGIAHKLPDMREVEPGF"
     gene            38794..39411
                     /gene="ccmA"
                     /locus_tag="RN951_000382"
     CDS             38794..39411
                     /gene="ccmA"
                     /locus_tag="RN951_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001300065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis heme-transporting ATPase
                     CcmA"
                     /protein_id="HDX2525446.1"
                     /translation="MLEARELLCERDERTLFSGLSFTLNAGEWVQITGSNGAGKTTLL
                     RLLTGLSRPDAGEVLWQGQPLHQVRDSYHQNLLWIGHQPGIKTRLTALENLHFYHRDG
                     DAAQCLEALAQAGLAGFEDIPVNQLSAGQQRRVALARLWLTRATLWILDEPFTAIDVN
                     GVDRLTQRMAQHTEQGGIVILTTHQPLNVAESKIRRISLTQTGAA"
     gene            39408..40070
                     /gene="ccmB"
                     /locus_tag="RN951_000383"
     CDS             39408..40070
                     /gene="ccmB"
                     /locus_tag="RN951_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmB"
                     /protein_id="HDX2525447.1"
                     /translation="MMFWRIFRLELRVAFRHSAEIANPLWFFLIVITLFPLSIGPEPQ
                     LLARIAPGIIWVAALLSSLLALERLFRDDLQDGSLEQLMLLPLPLPAVVLAKVMAHWM
                     VTGLPLLILSPLVAMLLGMDVYGWQVMALTLLLGTPTLGFLGAPGVALTVGLKRGGVL
                     LSILVLPLTIPLLIFATAAMDAASMHLPVDGYLAILGALLAGTATLSPFATAAALRIS
                     IQ"
     gene            40112..40849
                     /gene="ccmC"
                     /locus_tag="RN951_000384"
     CDS             40112..40849
                     /gene="ccmC"
                     /locus_tag="RN951_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmC"
                     /protein_id="HDX2525448.1"
                     /translation="MWKTLHQLAIPPRLYQICGWFIPWLAIASVVVLTVGWIWGFGFA
                     PADYQQGNSYRIIYLHVPAAIWSMGIYASMAVAAFIGLVWQMKMANLAVAAMAPIGAV
                     FTFIALVTGSAWGKPMWGTWWVWDARLTSELVLLFLYVGVIALWHAFDDRRLAGRAAG
                     ILVLIGVVNLPIIHYSVEWWNTLHQGSTRMQQSIDPAMRSPLRWSIFGFLLLSATLTL
                     MRMRNLILLMEKRRPWVSELILKRGRK"
     gene            40846..41055
                     /gene="ccmD"
                     /locus_tag="RN951_000385"
     CDS             40846..41055
                     /gene="ccmD"
                     /locus_tag="RN951_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmD"
                     /protein_id="HDX2525449.1"
                     /translation="MTPAFASWNEFFAMGGYAFFVWLAVVMTVIPLVVLVVHSVMQHR
                     AILRGVAQQRAREARLRAAQQQEAA"
     gene            41052..41531
                     /gene="ccmE"
                     /locus_tag="RN951_000386"
     CDS             41052..41531
                     /gene="ccmE"
                     /locus_tag="RN951_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c maturation protein CcmE"
                     /protein_id="HDX2525450.1"
                     /translation="MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEIL
                     YGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFTIYDAEGSVDVSYQGILPDL
                     FREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS"
     gene            41528..43471
                     /gene="ccmF"
                     /locus_tag="RN951_000387"
     CDS             41528..43471
                     /gene="ccmF"
                     /locus_tag="RN951_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis heme lyase CcmF"
                     /protein_id="HDX2525451.1"
                     /translation="MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAW
                     LLFMSVAGAFLVLVNAFVVNDFTVTYVASNSNTQLPVWYRVAATWGAHEGSLLLWVLL
                     MSGWTFAVAIFSQRIPLDIVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRD
                     LNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIASLLCGRLDSTYARFTRPWTLAAWIF
                     LTLGIVLGSAWAYYELGWGGWWFWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWT
                     LLLAISAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMVLVIGGSLLLFAARG
                     HKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFN
                     TMFTWLMVPFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLLLPWLFESKVVA
                     MTVLGLAMACWIAVLAIAEAALRISRGTKTTFSYWGMVAAHLGLAVTIVGIAFSQNYS
                     VERDVRMKSGDSVDIHEYRFTFRDVKEVTGPNWRGGVATIGVTRDGKPETVLYAEKRY
                     YNTAGSMMTEAAIDGGITRDLYAALGEELENGAWAVRLYYKPFVRWIWAGGLMMALGG
                     LLCLFDPRYRKRVSPQKTAPEAV"
     gene            43468..44025
                     /gene="dsbE"
                     /locus_tag="RN951_000388"
     CDS             43468..44025
                     /gene="dsbE"
                     /locus_tag="RN951_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbE"
                     /protein_id="HDX2525452.1"
                     /translation="MKRKVLLIPLIIFLAIAAALLWQLARNVEGDDPTNLESALIGKP
                     VPKFRLESLDNPGQFYQADVLTQGKPVLLNVWATWCPTCRAEHQYLNQLSAQGIRVVG
                     MNYKDDRQKAISWLKELGNPYALSLFDGDGMLGLDLGVYGAPETFLIDGNGIIRYRHA
                     GDLNPRVWEEEIKPLWEKYSKEAAQ"
     gene            44022..45074
                     /gene="ccmH"
                     /locus_tag="RN951_000389"
     CDS             44022..45074
                     /gene="ccmH"
                     /locus_tag="RN951_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis thiol:disulfide
                     oxidoreductase CcmH"
                     /protein_id="HDX2525453.1"
                     /translation="MRFLLGVLMLMISGSALATIDVLQFKDEAQEQQFRQLTEELRCP
                     KCQNNSIADSNSMIATDLRQKVYELMQEGKSKKEIVDYMVARYGNFVTYDPPLTPLTV
                     LLWVLPVVAIGIGGWVIYARSRRRVRVVPEAFPEQSVPEGKRAGYVAYLPGIVVALIV
                     AGVSYYQTGNYQQVKIWQQATAQAPALLDRALDPKADPLNEEEMSRLALGMRTQLQKN
                     PGDIDGWIMLGRVGMALGNASIATDAYATAYRLDPKNSDAALGYAEALTRSSDPNDNR
                     LGGELLRQLVRTDHSNIRVLSMYAFNAFEQQRFGEAVAAWEMMLKLLPANDTRRAVIE
                     RSIAQAMQHLSLQESK"
     gene            complement(45109..45756)
                     /gene="narP"
                     /locus_tag="RN951_000390"
     CDS             complement(45109..45756)
                     /gene="narP"
                     /locus_tag="RN951_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite response regulator protein NarP"
                     /protein_id="HDX2525454.1"
                     /translation="MPEATPFQVMIVDDHPLMRRGVRQLLELDPGFEVVAEAGDGASA
                     IDLANRLDIDVILLDLNMKGMSGLDTLNALRRDGVTAQIIILTVSDASSDVFALIDAG
                     ADGYLLKDSDPEVLLEAIRAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELD
                     VLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ"
     gene            46076..48667
                     /gene="yejO"
                     /locus_tag="RN951_000391"
                     /pseudo
     CDS             46076..48667
                     /gene="yejO"
                     /locus_tag="RN951_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311108.2"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter YejO"
     gene            complement(48771..48847)
                     /locus_tag="RN951_000392"
     tRNA            complement(48771..48847)
                     /locus_tag="RN951_000392"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(48811..48813),aa:Pro,seq:ggg)
     gene            complement(48922..50682)
                     /gene="pbgA"
                     /locus_tag="RN951_000393"
     CDS             complement(48922..50682)
                     /gene="pbgA"
                     /locus_tag="RN951_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin transport protein PbgA"
                     /protein_id="HDX2525455.1"
                     /translation="MVTHRQRYREKVSQMVSWGHWFALFNILLSLVIGSRYLFIADWP
                     TTLAGRIYSYVSIIGHFSFLVFATYLLILFPLTFIVGSQRLMRFLSVILATAGMTLLL
                     IDSEVFTRFHLHLNPIVWQLVINPDENEMARDWQLMFISVPVILLLELVFATWSWQKL
                     RSLTRRRRFARPLAAFLFIAFIASHVVYIWADANFYRPITMQRANLPLSYPMTARRFL
                     EKHGLLDAQEYQRRLIEQGNPDAVSVQYPLSELRYRDMGTGQNVLLITVDGLNYSRFE
                     KQMPALAGFAEQNISFTRHMSSGNTTDNGIFGLFYGISPSYMDGILSTRTPAALITAL
                     NQQGYQLGLFSSDGFTSPLYRQALLSDFSMPSVRTQSDEQTATQWINWLGRYAQEDNR
                     WFSWVSFNGTNIDDSNQQAFARKYSRAAGNVDDQINRVLNALRDSGKLDNTVVIITAG
                     RGIPLSEDEETFDWSHGHLQVPLVIHWPGTPAQRINALTDHTDLMTTLMQRLLHVSTP
                     ASEYSQGQDLFNPQRRHYWVTAADNDTLAITTPKKTLVLNNNGKYRTYNLRGERVKDE
                     KPQLSLLLQVLTDEKRFIAN"
     gene            complement(50702..50929)
                     /locus_tag="RN951_000394"
     CDS             complement(50702..50929)
                     /locus_tag="RN951_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YejL family protein"
                     /protein_id="HDX2525456.1"
                     /translation="MPQISRYSDEQVEQLLAELLNVLEKHKAPTDLSLMVLGNMVTNL
                     INTSIAPAQRQAIANSFARALQSSINEDKAH"
     gene            51111..52118
                     /gene="yejK"
                     /locus_tag="RN951_000395"
     CDS             51111..52118
                     /gene="yejK"
                     /locus_tag="RN951_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein YejK"
                     /protein_id="HDX2525457.1"
                     /translation="MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTETVVEMVAELH
                     RVYSAKNKAYGLFSEESELAQTLRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGF
                     VLFCHYRYLAVEYLLVAVLSNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETN
                     PESTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAE
                     RQNVRQQVYSYCNEQLQAGEEIELESLSKELAGVSEVSFTEFAAEKGYELEESFPADR
                     STLRQLTKFAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGG
                     N"
     gene            complement(52257..52541)
                     /gene="rplY"
                     /locus_tag="RN951_000396"
     CDS             complement(52257..52541)
                     /gene="rplY"
                     /locus_tag="RN951_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000494192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25"
                     /protein_id="HDX2525458.1"
                     /translation="MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAIELDH
                     DKVMNMQAKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLQHIDFVRA"
     gene            complement(52666..54426)
                     /locus_tag="RN951_000397"
     CDS             complement(52666..54426)
                     /locus_tag="RN951_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDX2525459.1"
                     /translation="MIFTLRPYQQEAVDATLNHFRRHKTPAVIVLPTGAGKSLVIAEL
                     ARLARGRVLVLAHVKELVAQNHAKYQALGLEADIFAAGLKRKESHGKVVFGSVQSVAR
                     NLDAFQGEFSLLIVDECHRIGDDEESQYQQILTHLTKVNPHLRLLGLTATPFRLGKGW
                     IYQFHYHGMVRGDEKALFRDCIYELPLRYMIKHSYLTPPERLDMPVVQYDFSRLQAQS
                     NGLFSEADLNRELKKQQRITPHIISQIMEFAATRKGVMIFAATVEHAKEIVGLLPAED
                     AALITGDTPGAERDVLIEDFKAQRFRYLVNVAVLTTGFDAPHVDLIAILRPTESVSLY
                     QQIVGRGLRLAPGKTDCLILDYAGNPHDLYAPEVGTPKGKSDNVPVQVFCPACGFANT
                     FWGKTTADGTLIEHFGRRCQGWFEDDDGHREQCDFRFRFKNCPQCNAENDIAARRCRE
                     CDTVLVDPDDMLKAALRLKDALVLRCSGMSLQHEHDEKGEWLKITYYDEDGADVSERF
                     RLQTPAQRTAFEQLFIRPHTRTPGIPLRWITAADILAQQALLRHPDFVVARMKGQYWQ
                     VREKVFDYEGRFRRAHELRG"
     gene            54575..55270
                     /gene="rsuA"
                     /locus_tag="RN951_000398"
     CDS             54575..55270
                     /gene="rsuA"
                     /locus_tag="RN951_000398"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase RsuA"
                     /protein_id="HDX2525460.1"
                     /translation="MRLDKFIAQQLGVSRAIAGREIRGNRVTVDGEIVRNAAFKLLPE
                     HDVAYDGNPLAQQHGPRYFMLNKPQGYVCSTDDPDHPTVLYFLDEPVAWKLHAAGRLD
                     IDTTGLVLMTDDGQWSHRITSPRHHCEKTYLVTLESPVADDTAEQFAKGVQLHNEKDL
                     TKPAVLEVITPTQVRLTISEGRYHQVKRMFAAVGNHVVELHRERIGGITLDADLAPGE
                     YRPLTEEEIASVV"
     gene            55298..56488
                     /gene="bcr"
                     /locus_tag="RN951_000399"
     CDS             55298..56488
                     /gene="bcr"
                     /locus_tag="RN951_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Bcr"
                     /protein_id="HDX2525461.1"
                     /translation="MTTRQHSSFAIVFILGLLAMLMPLSIDMYLPALPVISAQFGVPA
                     GSTQMTLSTYILGFALGQLIYGPMADSFGRKPVVLGGTLVFAAATVACALANTIDQLI
                     VMRFFHGLAAAAASVVINALMRDIYPKEEFSRMMSFVMLVTTIAPLMAPIVGGWVLVW
                     LSWHYIFWILALAAILASAMIFFLIKETLPPERRQPFHIRTTIGNFAALFRHKRVLSY
                     MLASGFSFAGMFSFLSAGPFVYIEINHVAPENFGYYFALNIVFLFVMTIFNSRFVRRI
                     GALNMFRSGLWIQFIMAAWMVISALLGLGFWSLVVGVAAFVGCVSMVSSNAMAVILDE
                     FPHMAGTASSLAGTFRFGIGAIVGALLSLATFNSAWPMIWSIAFCATSSILFCLYASR
                     PKKR"
     gene            56821..57165
                     /locus_tag="RN951_000400"
     CDS             56821..57165
                     /locus_tag="RN951_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2525462.1"
                     /translation="MTSLQLSIVHRLPQNYRWSAGFAGSKVEPIPQNGPCGDNSLVAL
                     KLLSPDGDNAWSVMYKLSQALSDIEVPCSVLECEGEPCLFVNRQDEFAATCRLKNFGV
                     AIAEPFSNYNPF"
     gene            complement(57169..58758)
                     /gene="yejF"
                     /locus_tag="RN951_000401"
     CDS             complement(57169..58758)
                     /gene="yejF"
                     /locus_tag="RN951_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter ATP-binding protein
                     YejF"
                     /protein_id="HDX2525463.1"
                     /translation="MTQTLLAIENLSVGFRHQQTVRTVVNDVSLQIEAGETLALVGES
                     GSGKSVTALSILRLLPSPPVEYLSGDIRFHGESLLHVSDQTLRGVRGNKIAMIFQEPM
                     VSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIRQAAKRLTDYPHQLSGG
                     ERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQGELNMGMLFITHNLS
                     IVRKLAHRVAVMQNGRCVEQNYAATLFASPTHPYTQKLLNSEPSGDPVPLPEPASTLL
                     DVEQLQVAFPIRKGILKRIVDHNVVVKNISFTLRAGETLGLVGESGSGKSTTGLALLR
                     LINSQGSIIFDGQPLQNLNRRQLLPIRHRIQVVFQDPNSSLNPRLNVLQIIEEGLRVH
                     QPTLSAAQREQQVIAVMHEVGLDPETRHRYPAEFSGGQRQRIAIARALILKPSLIILD
                     EPTSSLDKTVQAQILTLLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQG
                     PCARVFATPQQEYTRQLLALS"
     gene            complement(58760..59785)
                     /locus_tag="RN951_000402"
     CDS             complement(58760..59785)
                     /locus_tag="RN951_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX2525464.1"
                     /translation="MSRLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIAND
                     KPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQDPWLKQRLENNGWVLWAPIRFGA
                     TSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL
                     AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSL
                     VGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTL
                     TSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAILLSLLIFIGEAVRDA
                     FDPNKAV"
     gene            complement(59785..60879)
                     /locus_tag="RN951_000403"
     CDS             complement(59785..60879)
                     /locus_tag="RN951_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter permease YejB"
                     /protein_id="HDX2525465.1"
                     /translation="MGAYLIRRLLLVIPTLWAIITINFFIVQIAPGGPVDQAIAAIEF
                     GNAGVLPGAGGEGIRASHAQTGVGNISDSNYRGGRGLDPEVIAEITHRYGFDKPIHER
                     YFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAV
                     YNGSRFDVWSSAFIIIGYAIPAFLFAILLIVFFAGGSYFDLFPLRGLVSANFDSLPWY
                     QQITDYLWHITLPVLATVIGGFAALTMLTKNSFLDEVRKQYVVTARAKGVSEKNILWK
                     HVFRNAMLLVIAGFPATFISMFFTGSLLIEVMFSLNGLGLLGYEATVSRDYPVMFGTL
                     YIFTLIGLLLNIVSDISYTLVDPRIDFEGR"
     gene            complement(60880..62694)
                     /locus_tag="RN951_000404"
     CDS             complement(60880..62694)
                     /locus_tag="RN951_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311096.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDX2525466.1"
                     /translation="MIVRILLLFIALFTFGAQAQAIKESYAFAVLGEPRYAFNFNHFD
                     YVNPAAPKGGQITLSALGTFDNFNRYALRGNPGARTEQLYDTLFTTSDDEPGSYYPLI
                     AESARYADDYSWVEVAINPRARFHDGSPITARDVEFTFQKFMTEGVPQFRLVYKGTTV
                     KAIAPLTVRIELAKPGKEDMLSLFSLPVFPEKYWKDHKLSDPLATPPLASGPYRITSW
                     KMGQNIVYSRVKDYWAANLPVNRGRWNFDTIRYDYYLDDNVAFEAFKAGAFDLRMEND
                     AKNWATRYTGKNFDKKYIIKDEQKNESAQDTRWLAFNIQRPVFSDRRVREAITLAFDF
                     EWMNKALFYNAWSRTNSYFQNTEYAARNYPEAAELVLLAPMKKDLPSEVFTQIYQPPV
                     SKGDGYDRDNLLKADKLLNEAGWVLKGQQRVNATTGQPLSFELLLPASSNSQWVLPFQ
                     HSLQRLGINMDIRKVDNSQITNRMRSRDYDMMPRVWRAMPWPSSDLQISWSSEYINST
                     YNAPGVQSPVIDSLINQIIAAQGNKEKLLPLGRALDRVLTWNYYMLPMWYMAEDRLAW
                     WDKFSQPAVRPVYSLGIDTWWYDVNKAAKLPSARQQGE"
     gene            complement(62776..64332)
                     /locus_tag="RN951_000405"
     CDS             complement(62776..64332)
                     /locus_tag="RN951_000405"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HDX2525467.1"
                     /translation="MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYD
                     TLIIDVQKYLDTYFADLKSTTDRLQPLTLDTCQQANPELTARAAFSMNVRTFVLVKDK
                     KTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSG
                     VFAALNLNLTPSLFYSSRQEDYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIA
                     GIPLTVRLYADDWTWNDVWYAFLLGGMSGTVVGLLCYYLMSVRMRPGREIMTAIKREQ
                     FYVAYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAESQKMIVPLTQHLFEL
                     IARDAAELEKVLPVGVKFGINIAPDHLHSESFKADIQKLLTSLPAHHFQIVLEITERD
                     MLKEQEATQLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTET
                     ITSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLSERGVNFMQGYWISRPLPLDDFVR
                     WLKKPYTPQW"
     gene            complement(64513..65079)
                     /gene="mepS"
                     /locus_tag="RN951_000406"
     CDS             complement(64513..65079)
                     /gene="mepS"
                     /locus_tag="RN951_000406"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional murein DD-endopeptidase/murein
                     LD-carboxypeptidase"
                     /protein_id="HDX2525468.1"
                     /translation="MVKSQPILRYILRGIPAIAVAVLLSACSANNTAKNMHPETRAVG
                     SETSSLQASQDEFENLVRNVDVKSRIMDQYADWKGVRYRLGGSTKKGIDCSGFVQRTF
                     REQFGLELPRSTYEQQEMGKSVSRSNLRTGDLVLFRAGSTGRHVGIYIGNNQFVHAST
                     SSGVIISSMNEPYWKKRYNEARRVLSRS"
     gene            complement(65491..66204)
                     /gene="lpxT"
                     /locus_tag="RN951_000407"
     CDS             complement(65491..66204)
                     /gene="lpxT"
                     /locus_tag="RN951_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Kdo(2)-lipid A phosphotransferase"
                     /protein_id="HDX2525469.1"
                     /translation="MIKNLPQIVLLNIVGLALFLSWYIPVNHGFWLPIDADIFYFFNQ
                     KLVESKAFLWLVALTNNRAFDGCSLLAMGMLMLSFWLKENAPGRRRIVIMGLVMLLTA
                     VVLNQLGQALIPVKRASPTLTFTDINRVSELLSVPTKDASRDSFPGDHGMMLLIFSAF
                     MWRYFGKVAGLIALIIFVVFAFPRVMIGAHWFTDIIVGSMTVILIGLPWVLLTPLSDR
                     LITFFDKSLPGKNKHFQNK"
     gene            complement(66243..67229)
                     /gene="yeiR"
                     /locus_tag="RN951_000408"
     CDS             complement(66243..67229)
                     /gene="yeiR"
                     /locus_tag="RN951_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding GTPase YeiR"
                     /protein_id="HDX2525470.1"
                     /translation="MTRTNLITGFLGSGKTTSILHLLAHKDPNEKWAVLVNEFGEVGI
                     DGALLADSGALLKEIPGGCMCCVNGLPMQVGLNTLLRQGKPDRLLIEPTGLGHPKQIL
                     DLLTAPVYEPWIDLRATLCILDPRLLLDEKSASNGNFRDQLAAADIIVANKSDRATPE
                     SEQALQRWWQQNGGDRQLIHSEHGKVDGHLLDLPRRNLAELPASAAHSHQHVVKKGLA
                     ALSLPEHQRWRRSLNSGQGYQACGWIFDADTVFDTIGILEWARLAPVERVKGVLRIPE
                     GLVRINRQGDDLHIETQNVAPPDSRIELISSSEADWNALQSALLKLRLATTA"
     gene            complement(67347..68813)
                     /locus_tag="RN951_000409"
     CDS             complement(67347..68813)
                     /locus_tag="RN951_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HDX2525471.1"
                     /translation="MKTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLT
                     DRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYTVLEKGADGNQVIIVGAVHECLN
                     AKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHS
                     APGILVEALKRRRERGLTPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHV
                     SFPGTMVDRIVPAATDESLVEISQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVA
                     GVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQDRAFRHAARTLMLDE
                     QAPTLQIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLGRE
                     TDWSLLALGVAGWMRYVSGVDDAGNAIDVRDPLSDKIRELVAGSSSEQRVTALLSLRE
                     VFGDDLPDNPHFVQAIEQAWQQIVQFGAHQALLNTLKI"
     gene            complement(69036..69608)
                     /gene="yeiP"
                     /locus_tag="RN951_000410"
     CDS             complement(69036..69608)
                     /gene="yeiP"
                     /locus_tag="RN951_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007750416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P-like protein YeiP"
                     /protein_id="HDX2525472.1"
                     /translation="MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFS
                     DVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEE
                     ELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLST
                     GLVIQVPEYLSPGEKIRIHIEERRYMGRAD"
     gene            69763..70017
                     /locus_tag="RN951_000411"
     CDS             69763..70017
                     /locus_tag="RN951_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HDX2525473.1"
                     /translation="MKCRPGCGACCTAPSISSPIPGMPDGKPANTPCIQLDEQQRCKI
                     FTSPLRPKVCAGLQASAEMCGNSRQQAMTWLIDLEMLTAP"
     gene            complement(70014..71195)
                     /gene="setB"
                     /locus_tag="RN951_000412"
     CDS             complement(70014..71195)
                     /gene="setB"
                     /locus_tag="RN951_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter SetB"
                     /protein_id="HDX2525474.1"
                     /translation="MHNSPAVSSAKSFDLTSTAFLIVAFLTGIAGALQTPTLSIFLTD
                     EVHARPAMVGFFFTGSAVIGILVSQFLAGRSDKRGDRKSLIVFCCLLGVLACTLFAWN
                     RNYFVLLFVGVFLSSFGSTANPQMFALAREHADKTGREAVMFSSFLRAQVSLAWVIGP
                     PLAYALAMGFSFTVMYLSAAVAFIVCGVMVWLFLPSMQKELPLATGTVEAPRRNRRDT
                     LLLFVICTLMWGSNSLYIINMPLFIINELHLPEKLAGVMMGTAAGLEIPTMLIAGYFA
                     KRLGKRFLMRVAAVGGVCFYAGMLMAHSPVILLGLQLLNAIFIGILGGIGMLYFQDLM
                     PGQAGSATTLYTNTSRVGWIIAGSVAGIVAEIWNYHAVFWFAMVMIIATLFCLLRIKD
                     V"
     gene            71563..72693
                     /gene="fruB"
                     /locus_tag="RN951_000413"
     CDS             71563..72693
                     /gene="fruB"
                     /locus_tag="RN951_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused PTS fructose transporter subunit IIA/HPr
                     protein"
                     /protein_id="HDX2525475.1"
                     /translation="MFQLSVQDIHPGEKAGDKEEAIRQVAAALVQAGNVAEGYVNGML
                     AREQQTSTFLGNGIAIPHGTTDTRDQVLKTGVQVFQFPEGVTWGDGQVAYVAIGIAAS
                     SDEHLGLLRQLTHVLSDDSVAEQLKSATTAEELRALLMGEKQSEQLKLDNEMLTLDIV
                     ASDLLTLQALNAARLKEAGAVDATFVTKAINEQPLNLGQGIWLSDSAEGNLRSAIAVS
                     RAANAFDVDGETAAMLVSVAMNDDQPIAVLKRLADLLLDNKADRLLKADAATLLALLT
                     SDDAPTDDVLSAEFVVRNEHGLHARPGTMLVNTIKQFNSDITVTNLDGTGKPANGRSL
                     MKVVALGVKKGHRLRFTAQGADAEQALKAIGDAIAAGLGEGA"
     gene            72693..73631
                     /gene="fruK"
                     /locus_tag="RN951_000414"
     CDS             72693..73631
                     /gene="fruK"
                     /locus_tag="RN951_000414"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDX2525476.1"
                     /translation="MSRRVATITLNPAYDLVGFCPEIERGEVNLVKTTGLHAAGKGIN
                     VAKVLKDLGIDVTVGGFLGKDNQDGFQQLFSELGIANRFQVVQGRTRINVKLTEKDGE
                     VTDFNFSGFEVTPADWERFVTDSLSWLGQFDMVCVSGSLPSGVSPEAFTDWMTRLRSQ
                     CPCIIFDSSREALVAGLKAAPWLVKPNRRELEIWAGRKLPEMKDVIEAAHALREQGIA
                     HVVISLGAEGALWVNASGEWIAKPPSVDVVSTVGAGDSMVGGLIYGLLMRESSEHTLR
                     LATAVAALAVSQSNVGITDRPQLAAMMARVDLQPFN"
     gene            73648..75339
                     /gene="fruA"
                     /locus_tag="RN951_000415"
     CDS             73648..75339
                     /gene="fruA"
                     /locus_tag="RN951_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001538991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIBC"
                     /protein_id="HDX2525477.1"
                     /translation="MKTLLIIDANLGQARAYMAKTLLGAAARKAKLEIIDNPNDAEMA
                     IVLGDSIPNDSALNGKNVWQGDISRAVAHPELFLSEAKGHAKPYTAPVAATAPVDASG
                     PKRVVAVTACPTGVAHTFMAAEAIETEAKKRGWWVKVETRGSVGAGNAITPEEVAAAD
                     LVIVAADIEVDLAKFAGKPMYRTSTGLALKKTAQELDKAVAEATPYEPAGKAQTATTE
                     GKKESAGAYRHLLTGVSYMLPMVVAGGLCIALSFAFGIEAFKEPGTLAAALMQIGGGS
                     AFALMVPVLAGYIAFSIADRPGLTPGLIGGMLAVSTGSGFIGGIIAGFLAGYIAKLIS
                     TQLKLPQSMEALKPILIIPLISSLVVGLAMIYLIGKPVAGILEGLTHWLQTMGTANAV
                     LLGAILGGMMCTDMGGPVNKAAYAFGVGLLSTQTYGPMAAIMAAGMVPPLAMGLATMV
                     ARRKFDKAQQEGGKAALVLGLCFISEGAIPFAARDPMRVLPCCIVGGALTGAISMAIG
                     AKLMAPHGGLFVLLIPGAITPVLGYLVAIIAGTLVAGLAYAFLKRPETQIVEKNA"
     gene            75796..76737
                     /locus_tag="RN951_000416"
     CDS             75796..76737
                     /locus_tag="RN951_000416"
                     /EC_number="2.7.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine kinase"
                     /protein_id="HDX2525478.1"
                     /translation="MREKDYIVIIGSANIDVAGYSHHPLNYADSNPGKIKFTPGGVGR
                     NIAHNLALLGKNAWLLSAVGGDFYGQSLLAQTNQSGVYVDKCLIVPGENTSSYLSLLD
                     NTGEMLVAINDMSISDCISAEFLAQHQEFIRGAKVIVADCNLSEEALVWVLENSGETP
                     VFIDPVSAWKCVKIRDHLSKIHTLKPNRLEAETLSGIALSGREDVAKVAAWFHQHGLN
                     RLVLSMGGDGVYYSDINGESGWSAPIKTNVINVTGAGDAMMAGLASCWVDGMPFIDSV
                     RFAQGCSSMALACEYTNNPELSIANVRSLVENTECLN"
     gene            76725..77663
                     /gene="psuG"
                     /locus_tag="RN951_000417"
     CDS             76725..77663
                     /gene="psuG"
                     /locus_tag="RN951_000417"
                     /EC_number="4.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine-5'-phosphate glycosidase"
                     /protein_id="HDX2525479.1"
                     /translation="MSELTLSPELLQISAEVQDALKNKKPVVALESTIISHGMPFPQN
                     AQTAIEVEETIRKQGAVPATIAIIGGVMKVGLSKEEIELLGREGHNVTKVSRRDLPFV
                     VAAGKNGATTVASTMIIAALAGIKVFATGGIGGVHRGAEHTFDISADLQELANTNVTV
                     VCAGAKSILDLGLTTEYLETFGVPLIGYQTKALPAFFCRTSPFEVSIRLDSAREIARA
                     MAVKWQTGLNGGLVVANPIPEQFAMPEETINAAIDQAVAEAEEQGVIGKESTPFLLAR
                     VAELTGGDSLKSNIQLVFNNAILASEIAKEYQRLVG"
     gene            77757..79007
                     /locus_tag="RN951_000418"
     CDS             77757..79007
                     /locus_tag="RN951_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HDX2525480.1"
                     /translation="MDIMRSVVGMVVLLAIAFVLSVNKKSISLRTVGAALLLQIAIGG
                     IMLYFPPGKWAVEQAALGVHKVMSYSDAGSAFIFGSLVGPKMDVLFDGAGFIFAFRVL
                     PAIIFVTALISLLYYIGVMGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAI
                     VKPFIDRMNRNELFTAICSGMASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFAR
                     ILSPATEPSQVTFENLSFSETPPKSIIEAAANGAMTGLKIAAGVATVVMAFVAIIALI
                     NGIIGGVGGWFGFANVSLESIFGYVLAPLAWIMGVDWSDANLAGSLIGQKLAINEFVA
                     YLNFSPYLQTSGTLDVKTIAIISFALCGFANFGSIGVVVGAFSAISPKRAPEIAQLGL
                     RALAAATLSNLMSATIAGFFIGLA"
     gene            complement(79078..79776)
                     /gene="yeiL"
                     /locus_tag="RN951_000419"
     CDS             complement(79078..79776)
                     /gene="yeiL"
                     /locus_tag="RN951_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311082.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator YeiL"
                     /protein_id="HDX2525481.1"
                     /translation="MKEIHNNDLKQQLMSESAFKDCFLTDVSADTRLFHFLARDYIVQ
                     EGQQPSWLFYLTRGRARLYATLANGRVSLIDFFAAPCFIGEIELIDKDHEPRAVQAIE
                     ECWCLALPMKHYRPRLLNDTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNRLAAFIL
                     LSQEGDLYHEKHTQAAEYLGVSYRHLLYVLAQFIHDGLLTKSKKGYLIKNRKQLSGLA
                     LEMDPENKFSGMMQ"
     gene            79906..80847
                     /gene="rihB"
                     /locus_tag="RN951_000420"
     CDS             79906..80847
                     /gene="rihB"
                     /locus_tag="RN951_000420"
                     /EC_number="3.2.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosylpyrimidine nucleosidase"
                     /protein_id="HDX2525482.1"
                     /translation="MEKRKIILDCDPGHDDAIAIMMAAKHPAIDLLGITIVAGNQTLD
                     KTLINGLNVCQKLEINVPVYAGMPQPIMRQQIVADNIHGETGLDGPVFEPLTRQAEST
                     HAVKYIIDTLMASDGDITLVPVGPLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFT
                     PSAEFNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPDVIARMERAGGPAGELFSD
                     IMNFTLKTQFENYGLAGGPVHDATCIGYLINPDGIKTQEMYVEVDVNSGPCYGRTVCD
                     ELGVLGKPANTKVGITIDTDWFWGLVEECVRGYIKTH"
     gene            80947..82197
                     /locus_tag="RN951_000421"
     CDS             80947..82197
                     /locus_tag="RN951_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HDX2525483.1"
                     /translation="MDVMRSVLGMVVLLAIAFLLSVNKKKISLRTVGAALVLQVVIGG
                     IMLWLPPGRWVAEKVAFGVHKVMAYSDAGSAFIFGSLVGPKMDTLFDGAGFIFGFRVL
                     PAIIFVTALVSILYYIGVMGILIRILGGIFQKALNISKIESFVAVTTIFLGQNEIPAI
                     VKPFIDRLNRNELFTAICSGMASIAGSTMIGYAALGVPVEYLLAASLMAIPGGILFAR
                     LLSPATESSQVSFNNLSFTETPPKSIIEAAATGAMTGLKIAAGVATVVMAFVAIIALI
                     NGIIGGVGGWFGFAHASLESILGYLLAPLAWVMGVDWSDANLAGSLIGQKLAINEFVA
                     YLNFSPYLQTGGTLDAKTVAIISFALCGFANFGSIGVVVGAFSAVAPHRAPEIAQLGL
                     RALAAATLSNLMSATIAGFFIGLA"
     gene            complement(82253..83341)
                     /locus_tag="RN951_000422"
     CDS             complement(82253..83341)
                     /locus_tag="RN951_000422"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDX2525484.1"
                     /translation="MNDREKQILKILRRNPLIQQNEIADILQISRSRVAAHIMDLMRK
                     GLIKGKGYILTEQDYCVVVGAINMDIRGMADIRYPQAASHPGSVHCSAGGVGRNIAHN
                     LALLGRDVHLISAIGNDFYGETLLEETRRAGVNVSNCIRLHGHSTATYLAIANKQEET
                     ILAINDTHILQQLTPQLLNTSRDLIRHAGVVLADCNLTPEALEWVFTIADEIPMFVDT
                     VSEFKANKVKNWYSRIHTLKPTQNELEILWGQPIKDDNDRIRAVNSLHQQGVKRIFVY
                     LKDESVFCSDKDGEQFLLTAPAHTTVDSFGADDGFMAGLVYSFLEGYSFRDSARFAVA
                     CAAISRASGSLNNPTLSADNALSLVPMV"
     gene            complement(83345..84202)
                     /gene="nfo"
                     /locus_tag="RN951_000423"
     CDS             complement(83345..84202)
                     /gene="nfo"
                     /locus_tag="RN951_000423"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HDX2525485.1"
                     /translation="MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPL
                     TTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLG
                     LSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEH
                     LAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLN
                     DAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLK
                     AQQTEKAVA"
     gene            complement(84276..85325)
                     /locus_tag="RN951_000424"
     CDS             complement(84276..85325)
                     /locus_tag="RN951_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HDX2525486.1"
                     /translation="MTNITLQKQHRTLWHFIPGLALSAVITGVALWGGSIPAVAGAGF
                     SALTLAILLGMVLGNTIYPHIWKSCDGGVLFAKQYLLRLGIILYGFRLTFSQIADVGI
                     SGIIIDVLTLSSTFLLACFLGQKVFGLDKHTSWLIGAGSSICGAAAVLATEPVVKAEA
                     SKVTVAVATVVIFGTVAIFLYPAIYPLMSQWFSPETFGIYIGSTVHEVAQVVAAGHAI
                     SPDAENAAVISKMLRVMMLAPFLILLAARVKQLSGANSGEKSKITIPWFAILFIVVAI
                     FNSFHLLPQSVVNMLVTLDTFLLAMAMAALGLTTHVSALKKAGAKPLLMALVLFAWLI
                     VGGGAINYVIQSVIA"
     gene            85424..86305
                     /locus_tag="RN951_000425"
     CDS             85424..86305
                     /locus_tag="RN951_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX2525487.1"
                     /translation="MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQ
                     LGVQLFDRVGKRLVVNEHGRLLYPRALALLEQAVEIEQLFREDNGAIRIYASSTIGNY
                     ILPAVIARYRHDYPQLPIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLE
                     DELVVFAAPTSPLARGPVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMEL
                     GNSEAIKHAVRHGLGISCLSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLS
                     NALRRFLDYCDPANVPR"
     gene            86510..87979
                     /gene="lysP"
                     /locus_tag="RN951_000426"
     CDS             86510..87979
                     /gene="lysP"
                     /locus_tag="RN951_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-specific permease"
                     /protein_id="HDX2525488.1"
                     /translation="MVSETKTTEAPGLRRELKARHLTMIAIGGSIGTGLFVASGATIS
                     QAGPGGALLSYMLIGLMVYFLMTSLGELAAYMPVSGSFATYGQNYVEEGFGFALGWNY
                     WYNWAVTIAVDLVAAQLVMSWWFPDTPGWIWSALFLGVIFLLNYISVRGFGEAEYWFS
                     LIKVTTVIVFIIVGVLMIIGIFKGAQPAGWSNWTIGEAPFAGGFAAMIGVAMIVGFSF
                     QGTELIGIAAGESEDPAKNIPRAVRQVFWRILLFYVFAILIISLIIPYTDPSLLRNDV
                     KDISVSPFTLVFQHAGLLSAAAVMNAVILTAVLSAGNSGMYASTRMLYTLACDGKAPR
                     IFAKLSRGGVPRNALYATTVIAGLCFLTSMFGNQTVYLWLLNTSGMTGFIAWLGIAIS
                     HYRFRRGYVLQGHDINDLPYRSGFFPLGPIFAFILCLIITLGQNYEAFLKDTIDWGGV
                     AATYIGIPLFLIIWFGYKLIKGTHFVRYSEMKFPQNDKK"
     gene            88272..90263
                     /gene="cirA"
                     /locus_tag="RN951_000427"
     CDS             88272..90263
                     /gene="cirA"
                     /locus_tag="RN951_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catecholate siderophore receptor CirA"
                     /protein_id="HDX2525489.1"
                     /translation="MFRLNPFVRVGLCLSAISCAWPVLAVDDDGETMVVTASSVEQNL
                     KDAPASISVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRGLDSSYTLIL
                     VDGKRVNSRNAVFRHNDFDLNWIPVDSIERIEVVRGPMSSLYGSDALGGVVNIITKKI
                     GQKWSGTVTVDTTIQEHRDRGDTYNGQFFTSGPLIDGVLGMKAYGSLAKREKDDPQNS
                     TTTDTGETPRIEGFSSRDGNVEFAWTPNQNHDFTAGYGFDRQDRDSDSLDKNRLERQN
                     YSVSHNGRWDYGTSELKYYGEKVENKNPGNSSPITSESNAVDGKYTLPLTAINQFLTV
                     GGEWRHDKLSDAVNLTGGTSSKTSASQYALFVEDEWRIFEPLALTTGVRMDDHETYGE
                     HWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWTSNSCRGACKIVGSPDLKPE
                     TSESWELGLYYMGEEGWLEGVESSVTVFRNDVKDRISISRTSDVNAAPGYQNFVGFET
                     GANGRRIPVFSYYNVNKARIQGVETELKIPFNDEWKLSINYTYNDGRDVSNGENKPLS
                     DLPFHTANGTLDWKPLALEDWSFYVSGHYTGQKRADSATAKTPGGYTIWNTGAAWQVT
                     KDVKLRAGVLNLGDKDLSRDDYSYNEDGRRYFMAVDYRF"
     gene            complement(90295..91131)
                     /gene="yeiG"
                     /locus_tag="RN951_000428"
     CDS             complement(90295..91131)
                     /gene="yeiG"
                     /locus_tag="RN951_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HDX2525490.1"
                     /translation="MEMLEEHRCFEGWQQRWRHDSSTLNCPMTFSIFLPPPRDHTPPP
                     VLYWLSGLTCNDENFTIKAGAQRVAAELGIVLVMPDTSPRGEQVANDDGYDLGQGAGF
                     YLNATQPPWATHYRMYDYLRDELPALVQSQFNVSDRCAISGHSMGGHGALIMALKNPG
                     KYTSVSAFAPIVNPCSVPWGIKAFSSYLGEDKNAWLEWDSCALMYASNAQDAIPTLID
                     QGDNDQFLADQLQPAVLAEAARQKAWPMTLRIQPGYDHSYYFIASFIEDHLRFHAQYL
                     LK"
     gene            91389..92057
                     /gene="folE"
                     /locus_tag="RN951_000429"
     CDS             91389..92057
                     /gene="folE"
                     /locus_tag="RN951_000429"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HDX2525491.1"
                     /translation="MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHM
                     TEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMVTV
                     RDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQIL
                     IALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAV
                     RHHN"
     gene            92074..93231
                     /locus_tag="RN951_000430"
     CDS             92074..93231
                     /locus_tag="RN951_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF418 family protein"
                     /protein_id="HDX2525492.1"
                     /translation="MERNVTLDFVRGVAILGILLLNISAFGLPKAAYLNPAWYGAITP
                     QDAWTWAFLDLIAQVKFLTLFALLFGAGLQMLLPRGRRWIQSRLTLLVLLGFIHGLLF
                     WDGDILLAYGLVGLICWRLVRDAPSVKSLFNTGVMLYLVGLGVLLLLGLISDSQTSRA
                     WTPDASAILYEKYWKLHGGVDAISNRADGVGNSLLALGAQYGWQLAGMMLIGAALMRS
                     GWLKGQFSLRHYRRTGFVLVAIGVTINLPAIALQWQLDWAYRWCAFLLQMPRELSAPF
                     QAIGYASLFYGFWPQLSRFKLVLAIACVGRMALTNYLLQTLICTTLFYHLGLFMHFDR
                     LELLAFVIPVWLANILFSVIWLRYFRQGPVEWLWRQLTLRAAGTAISKTSR"
     gene            93373..94413
                     /gene="galS"
                     /locus_tag="RN951_000431"
     CDS             93373..94413
                     /gene="galS"
                     /locus_tag="RN951_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708050.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalS"
                     /protein_id="HDX2525493.1"
                     /translation="MITIRDVARQAGVSVATVSRVLNNSTLVSADTREAVMKAVSELD
                     YRPNANAQALATQVSDTIGVVVMDVSDAFFGALVKAVDLVAQQHQKYVLIGNSYHEAE
                     KERHAIEVLIRQRCNALIVHSKALSDDELAQFMDNIPGMVLINRVVPGYAHRCVCLDN
                     LSGARMATRMLLNNCHQRIGYLSSSHGIEDDAMRKAGWMSALKEQDIIPPESWIGTGT
                     PDMPGGEAAMVELLGRNLQLTAVFAYNDNMAAGALTALKDNGIAIPLHLSIIGFDDIP
                     IARYTDPQLTTVRYPIASMAKLATELALQGAAGNIDPRASHCFMPTLVRRHSVATRQN
                     AATITNSTNQAM"
     gene            94693..95691
                     /gene="mglB"
                     /locus_tag="RN951_000432"
     CDS             94693..95691
                     /gene="mglB"
                     /locus_tag="RN951_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/glucose ABC transporter
                     substrate-binding protein MglB"
                     /protein_id="HDX2525494.1"
                     /translation="MNKKVLTLSAVMASMLFGAAAHAADTRIGVTIYKYDDNFMSVVR
                     KAIEQDAKAAPDVQLLMNDSQNDQSKQNDQIDVLLAKGVKALAINLVDPAAAGTVIEK
                     ARGQNVPVVFFNKEPSRKALDSYDKAYYVGTDSKESGIIQGDLIAKHWAANQGWDLNK
                     DGQIQFVLLKGEPGHPDAEARTTYVIKELNDKGIKTEQLQLDTAMWDTAQAKDKMDAW
                     LSGPNANKIEVVIANNDAMAMGAVEALKAHNKSSIPVFGVDALPEALALVKSGALAGT
                     VLNDANNQAKATFDLAKNLADGKGAADGTNWKIENKVVRVPYVGVDKDNLAEFSKK"
     gene            95752..97272
                     /gene="mglA"
                     /locus_tag="RN951_000433"
     CDS             95752..97272
                     /gene="mglA"
                     /locus_tag="RN951_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020883197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     ATP-binding protein MglA"
                     /protein_id="HDX2525495.1"
                     /translation="MVSSTTPSSGEYLLEMSGINKSFPGVKALDNVNLKVRPHSIHAL
                     MGENGAGKSTLLKCLFGIYQKDSGTILFQGKEIDFHSAKEALENGISMVHQELNLVLQ
                     RSVMDNMWLGRYPTKGMFVDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEI
                     AKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDE
                     VTVLRDGQWIATEPLAGLTMDKIIAMMVGRSLNQRFPDKENKPGEVILEVRNLTSLRQ
                     PSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKQINNHNANE
                     AINHGFALVTEERRSTGIYAYLDISFNSLISNIRNYKNKVGLLDNSRMKSDTQWVIDS
                     MRVKTPGHRTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIA
                     ELAKKGKGIIIISSEMPELLGITDRILVMSNGLVSGIVDTKTTTQNEILRLASLHL"
     gene            97288..98298
                     /gene="mglC"
                     /locus_tag="RN951_000434"
     CDS             97288..98298
                     /gene="mglC"
                     /locus_tag="RN951_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     permease MglC"
                     /protein_id="HDX2525496.1"
                     /translation="MSALNKKSFLTYLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSN
                     ILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAAVVAATLLQSMDNANKVFPEMAT
                     MPIALVILIVCAIGAVIGLINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASP
                     ISGFDSGFSTFAQGFVALGSFRLSYITFYALIAVAFVWVLWNKTRFGKNIFAIGGNPE
                     AAKVSGVNVGLNLLMIYALSGVFYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGG
                     VSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAIIIFAVALDSLKYAR
                     KK"
     gene            complement(98369..99604)
                     /gene="preA"
                     /locus_tag="RN951_000435"
     CDS             complement(98369..99604)
                     /gene="preA"
                     /locus_tag="RN951_000435"
                     /EC_number="1.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416652.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreA"
                     /protein_id="HDX2525497.1"
                     /translation="MLTKDLSITFCGVKFPNPFCLSSSPVGNCYEMCAKAYDTGWGGV
                     VFKTIGFFIANEVSPRFDHLVKEDTGFIGFKNMEQIAEHPLEENLAALRQLKEDYPDK
                     VLIASIMGENEQQWEELARLVQEAGADMIECNFSCPQMTSHAMGSDVGQSPELVEKYC
                     RAVKRGSTLPMLAKMTPNIGDMCEVALAAKRGGADGIAAINTVKSITNIDLNQKIGMP
                     IVNGKSSISGYSGKAVKPIALRFIQQMRTHPELCDFPISGIGGIETWEDAAEFLLLGA
                     ATLQVTTGIMQYGYRIVEDMASGLSHYLADQGFDSLQEMVGLANNNIVPAEDLDRSYI
                     VYPRINLDKCVGCGRCYISCYDGGHQAMEWSEKTRTPHCNTEKCVGCLLCGHVCPVGC
                     IELGEVKFKKGEKEHPVTL"
     gene            complement(99598..100836)
                     /gene="preT"
                     /locus_tag="RN951_000436"
     CDS             complement(99598..100836)
                     /gene="preT"
                     /locus_tag="RN951_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreT"
                     /protein_id="HDX2525498.1"
                     /translation="MPQQNYLDELTPAFTPLLAIKEASRCLLCHDAPCSQACPAQTDP
                     GKFIRSIYFRNFKGAAETIRENNALGAVCARVCPTEKLCQSGCTRAGVDTPIDIGRLQ
                     RFVTDFEQQTGMEIYQPGTKTLGKVAIIGAGPAGLQASVTLTNQGYDVTIYEKEAHPG
                     SWLRNGIPQFRLPQSVLDAEIARIEKMGVTIKCNNEVGNTLTLEQLKAENRAVLVTVG
                     LSSGSGLPLFEHSDVEIAVDFLQRVRQAQGDISIPQSALIIGGGDVAMDVASTLKVLG
                     CQAVTCVAREELDEFPASEKEFASARELGVSIIDGFTPVAVEGNKVTFKHVRLPGELT
                     MAADKIILAVGQHARLDAFAELEPQRNTIKTQNYQTRDPQVFAAGDIVEGDKTVVYAV
                     KTGKEAAEAIHHYLEGACSC"
     gene            complement(101155..101394)
                     /locus_tag="RN951_000437"
     CDS             complement(101155..101394)
                     /locus_tag="RN951_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2542 family protein"
                     /protein_id="HDX2525499.1"
                     /translation="MDVQQFFVVAVFFLIPIFCFREAWKGWRAGAIDKRVKNAPEPVY
                     VWRAKNPGLFFAYMVAYIGFGILSIGMIVYLIFYR"
     gene            complement(101397..102116)
                     /gene="sanA"
                     /locus_tag="RN951_000438"
     CDS             complement(101397..102116)
                     /gene="sanA"
                     /locus_tag="RN951_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane permeability protein SanA"
                     /protein_id="HDX2525500.1"
                     /translation="MLKRVFLSLLVLIGLLLLTVLGLDRWMSWKTAPYIYDELQDLPY
                     RQVGVVLGTAKYYRTGVINQYYRYRIQGAINAYNSGKVNYLLLSGDNALQSYNEPMTM
                     RKDLIAAGVDPSDIVLDYAGFRTLDSIVRTRKVFDTNDFIIITQRFHCERALFIALHM
                     GIQAQCYAVPSPKDMLSVRIREFAARFGALADLYIFKREPRFLGPLVPIPAMHQVPED
                     AQGYPAVTPEQLLELQKKQGK"
     gene            complement(102266..103150)
                     /gene="cdd"
                     /locus_tag="RN951_000439"
     CDS             complement(102266..103150)
                     /gene="cdd"
                     /locus_tag="RN951_000439"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDX2525501.1"
                     /translation="MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSA
                     TGLDEDALAFALLPLAAACARTPLSNFNVGAIARGVSGTWYFGANMEFIGATMQQTVH
                     AEQSAISHAWLSGEKALAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDY
                     LPDAFGPKDLEIKTLLMDEQDHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECK
                     DGRIFSGSYAENAAFNPTLPPLQGALILLNLKGYDYPDIQRAVLAENADAPLIQWDAT
                     SATLKALGCHSIDRVLLA"
     gene            complement(103280..103975)
                     /locus_tag="RN951_000440"
     CDS             complement(103280..103975)
                     /locus_tag="RN951_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidB/LrgB family autolysis modulator"
                     /protein_id="HDX2525502.1"
                     /translation="MMANIWWSLPLTLIVFFAARKLAARYKFPLLNPLLVAMVVIIPF
                     LMLTGISYDSYFKGSEVLNDLLQPAVVALAYPLYEQLHQIRARWKSIITICFIGSVVA
                     MVTGTSVALLMGASPEIAASILPKSVTTPIAMAVGGSIGGIPAISAVCVIFVGILGAV
                     FGHTLLNAMRIRTKAARGLAMGTASHALGTARCAELDYQEGAFSSLALVLCGIITSLI
                     APFLFPIILAVMG"
     gene            complement(103972..104370)
                     /locus_tag="RN951_000441"
     CDS             complement(103972..104370)
                     /locus_tag="RN951_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HDX2525503.1"
                     /translation="MSKTLNIIWQYLRAFVLIYACLYAGIFIASLLPVTIPGSIIGML
                     ILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAV
                     STLVVFLVVSWSSQLVHGERKVVGQKGSEE"
     gene            104609..105556
                     /gene="dusC"
                     /locus_tag="RN951_000442"
     CDS             104609..105556
                     /gene="dusC"
                     /locus_tag="RN951_000442"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(16) synthase DusC"
                     /protein_id="HDX2525504.1"
                     /translation="MRVLLAPMEGVLDSLVRELLTEVNDYDLCITEFVRVVDQLLPVK
                     VFHRICPELQNASRTPSGTLVRVQLLGQFPQWLAENAARAVELGSWGVDLNCGCPSKT
                     VNGSGGGATLLKDPELIYQGAKAMREAVPAHLPVSVKVRLGWDSGEKKFEIADAVQQA
                     GATELVVHGRTKEQGYRAEHIDWQAIGEIRQRLNIPVIANGEIWDWQSAQQCIAISGC
                     DAVMIGRGALNIPNLSRVVKYNEPRMPWPEVVALLQKYTRLEKQGDTGLYHVARIKQW
                     LSYLRKEYDEATGLFQHVRVLNNSPDIARAIQAIDIEKL"
BASE COUNT        25612 a        25919 c        28329 g        25773 t
ORIGIN      
        1 attatgacgc actgatacta ttcatcaaat aataacaaaa tagccattgc atcgggttgg
       61 acaatttaca aaagaaagat aacccatatt gtataatgcg tttaaatatg ccgtcttata
      121 taaaatgatg gttagatgaa tatgcggatt atctttctac gcaaggagta tttatctcta
      181 ctcccgtcaa tgattgcatc tcttttctct gctaacggtt tcgcggcggc cattgattta
      241 tgcaagggat atgatatcaa agcgagttgt cacgccagca ggcaaagcct ttcaggcatt
      301 acgcaggact ggagtgtcgc cgatgggcaa tggctggttt tttcggatat gaccaataac
      361 gccagcggag gagccgtatt tttgcaacaa ggagcggaat tttcactatt accagaaaat
      421 gaaactggaa tgactctgtt tgccaataac accgttacag gagaatataa taacggcggg
      481 gccatatttg ctaaagaaaa ctcaacgctg aatcttactg atgttatttt ttccggtaac
      541 gtcgcaggcg gctatggtgg cgcaatctat tcttctggta ctaatgatac tggtgccgtc
      601 gatttacgtg tcactaacgc catgtttcgc aataatatcg ctaatgatgg caaaggtggc
      661 gcaatttata ccattaataa tgacgtctat ttaagtgatg ttatttttga taacaaccag
      721 gcatatacat caacaagtta cagtgatggc gatggcgggg caatcgatgt taccgataat
      781 aatagcgaca gcaagcatcc ttcaggttat acgataataa ataacactgc ctttacaaat
      841 aacactgccg aaggttatgg cggggcgata tataccaata gcgcgacggc tccctatctt
      901 attgatattt ctgttgatga cagctacagc cagaacggcg gcgtgttagt ggatgagaac
      961 aacagcgcag caggctatgg agatggtcct tccactgcgg cgggtggctt tatgtatctc
     1021 ggcttaagtg aagttacctt tgatattgcc gacggaaaaa cgctggttat tggcaataca
     1081 gagaatgacg gagctgttga ctctattgct ggtaccgggt tgatcaccaa aacaggttcc
     1141 ggcgatctgg tacttaatgc agataacaat gactttactg gtgagatgca gattgaaaac
     1201 ggtgaagtta ccctgggccg cagcaactcc ctgatgaatg tcggcgatac gcattgccag
     1261 gacgatccgc aagactgcta cggtctgacg atagggagta ttgataagta ccagaatcag
     1321 gcagagctaa acgttggctc cacccaacaa acctttgtgc actcattgac gggctttcag
     1381 aatggcactt taaatatcga tgctggtggc aatgttactg ttaatcaagg cagttttgct
     1441 ggcaccatcg aaggtgctgg tcagctcacc attgcgcaaa acggcagcta cgtgctgtcg
     1501 ggggcgcagt cgatggcgct aaccggcgat atagtcgttg atgatggtgc ggtgctttcg
     1561 ctggaaggcg acgcggcaga tctcgccgct ctccaggacg atccgcagtc gatcgtgtta
     1621 aacggcggtg tgctcgatct ctctgatttc tccacctggc agagcggcac atcatacaat
     1681 gatggccttg aagtcagtgg cagcagcgga acggttatcg gcagtcagga tgtggtagat
     1741 cttgcaggtg gcgacaattt gcatatcggc ggcgacggga aagatggcgt ctacgtggtg
     1801 gtcgatgcga gcgacgggca ggtaagtctg gcaaacaata atagttattt gggcacaaca
     1861 caaatcgcct ccggtacgct gatggtgagc gacaactcgc agcttggaga tacccactat
     1921 aaccgccagg ttatctttac cgataagcaa caagaaagcg tgatggagat tactgccaat
     1981 gtcgatactc gctctacgac gactgagcat gggcgtgata ttgaaatgcg cgccgacggt
     2041 gaagtggcag ttgatgcggg ggtagacacg cagtggggcg cactgatggc tgacagcagc
     2101 gggcagcatc aggatgaggg tagcacattt actaaaacgg gggcgggtac gctggagctg
     2161 accgccagcg gtacaacgca gtcggcagta cgtgtcgaag aaggcaccct gaaaggcgat
     2221 gttgcggata tctttcctta tgcttcgtca ctgtgggtcg gtgatggggc gacgttcgtt
     2281 actggcgcgg atcaggatat tcagtctatc gatgctactt ccagcggcac tatcgatatc
     2341 agcgatggta cggttttgcg tctgaccggg caggatactt ccgtcgccct taatgcctca
     2401 ttgtttaacg gcgatgggac gctggtgaat gccaccgatg gcgtgacgtt gacaggtgag
     2461 cttaatacca accttgaaac tgacagcctg acctatcttt ccgacgtgac ggttaatggc
     2521 aatctgacca atacgtccgg tgcggttagc ctgcaaaatg gcgtcgctgg cgatacgctg
     2581 acggtaaacg gtgattatac cggcggcggt acgctactgc tcgatagcga attaaacggc
     2641 gatgactcgg taagcgatca attggtgttg aacggtaata ctgctggcaa cacaactgtg
     2701 gtggttaact ccattacagg gattggtgag ccgacatcga caggcattaa agtggttgat
     2761 ttcgcagccg atcccacgca gtttcaaaac aatgcgaagt tcagtctggc aggcagcggc
     2821 tacgtcaata tgggagcata tgactacacg ctggtggaag ataacaacga ctggtatctg
     2881 cgatcgcaag aagtaacgcc accattgcca cctgatccag accctgaccc aacacccgat
     2941 cctgacccaa cacccgatcc aatccccgct taccagccgg tgctgaatgc caaagttggc
     3001 ggttatctca ataatctgcg ggcggcaaat caggcgttta tgatggagcg acgcgatcat
     3061 gcaggtggca atggtcagac gctgaattta cgtgttatcg gcggacgtta tcattacacg
     3121 gcggcagggc aactggctca gcatgaagac acttctacgg tgcagcttag cggtgacctg
     3181 tttagcgggc gctggggcga tgatggcgag tggatgcttg gggcggttgg tggctacagt
     3241 gataatcagg gcgagagccg ctcgaatatg accggaactc gcgccgataa ccagaaccac
     3301 ggttatgccg ttgggctgac ctcaagctgg tatcagcacg gtaatcagaa gcagggggcc
     3361 tggctggata gctggctgca atacgcgtgg tttaacaatg atgtttccga acaagacgat
     3421 ggcacagatc attaccactc gtcggggatt atcgcctcgc tggaagccgg gtatcagtgg
     3481 ttaccggggc gtggtgtggt gattgaaccg caggcgcagg tgatttatca gggcgtgcag
     3541 caggatgatt ttaccgccgc taaccatgcg cgcgtgtcac aatcgcaggg ggatgatatt
     3601 cagacgcggc tgggtttaca cagcgaatgg cgtaccgcgg ttggtgtcac accaacatta
     3661 gatctgaatt attatcacga tccccatgcg acggaaattg aagaagatgg cagcactatc
     3721 agtgacgatg cggtgaagcg acggggtgaa ataaaagtgg gagtcacggg caatatcagt
     3781 cagcgagtgt ccctgcgcgg cagcgtggcg tggcagaaag ggagtgatga ttttgcccag
     3841 acggcagggt ttttgtcgat gacggtgaaa tggtagctgc tttgcgcccg gcattgtagc
     3901 cggatgtggt gcgagcacct tatccggcta acaattttat ttattctgcg tgtgcagcat
     3961 atagttcaca tccacgccgg ggccgagttt aaaagtatta gtgatcgggt tgtaatgtag
     4021 cccggttata tgtcgctctt taaggcttgt ctgatctacc cagccaagca gttctgccgg
     4081 tttaataaac ttcttcacat catgcgtgcc tttgggcacc atgcgcaaaa tatattccgc
     4141 gccaaccacc gccatcagcc atgacttgcc gttgcggtta agcgtcgaga aaaagacatc
     4201 gccgcccggt ttcaccagtt gcgcacaggc tctgaccact gactgcggat cggggacgtg
     4261 ctccagcatc tccatgcagg tcaccacatc atactgcccg gcatgttttg ccgcgtgctc
     4321 ttccacggtt tcctgcacgt aatccacctg aatgccgctt tccagtgcgt gcagttttgc
     4381 cacctgcaat ggctcaaagc ccatatccag accggtcacc gtcgcgcctt cgcgcgccat
     4441 actctcggcc agaatgccgc cgccacaacc gacatcgagc acctttttgc caaataaacc
     4501 gccagcacgc tcggcaatat agcccagacg cagcgggtta atgcggtgca gcggtttgaa
     4561 ctcaccttcc agatcccacc agcgggaggc gacggcttca aatttagcga tctcttcgtg
     4621 gtctacgtta tggtttaccg gcgatttttc ggcattcatt agcacttcta ctccgtaatt
     4681 ggcaagacaa acgagtatat caggcattgg atgtgaataa agcgtatagg tttacctcaa
     4741 actgcgcggc tgtgttataa tttgcgacct ttgaatccgg gatacagtag agggatagcg
     4801 gttagatgag cgaccttgcg agagaaatta caccggtcaa cattgaggaa gagctgaaga
     4861 gctcctatct ggattatgcg atgtcggtca ttgttggccg tgcgctgcca gatgtccgag
     4921 atggcctgaa gccggtacac cgtcgcgtac tttacgccat gaacgtacta ggcaatgact
     4981 ggaacaaagc ctataaaaaa tctgcccgtg tcgttggtga cgtaatcggt aaataccatc
     5041 cccatggtga cttggcggtt tataacacga tcgtccgtat ggcgcagcca ttctcgctgc
     5101 gttacatgct ggtagacggt cagggtaact tcggttccat cgacggcgac tctgcggcgg
     5161 caatgcgtta tacggaaatc cgtctggcga aaattgccca tgaactgatg gccgatctcg
     5221 aaaaagagac ggtcgatttc gttgataact atgacggcac ggaaaaaatt cccgacgtca
     5281 tgccaaccaa aattcctaac ctgctggtga acggttcttc cggtatcgcc gtaggtatgg
     5341 caaccaacat cccgccgcac aacctgacgg aagtcatcaa cggttgtctg gcgtatatcg
     5401 atgatgaaga catcagcatt gaagggctga tggaacacat cccggggccg gacttcccga
     5461 cggcggcaat cattaacggt cgtcgcggta ttgaagaagc ttaccgtacc ggttgcggca
     5521 aggtgtatat ccgcgctcgc gcagaagtgg aagttgacgc caaaaccggt cgtgaaacca
     5581 ttatcgtcca cgaaattccg tatcaggtaa acaaagcgcg cctgatcgag aagattgcgg
     5641 aactggtaaa agaaaaacgc gtggaaggca tcagcgcgct gcgtgacgag tctgacaaag
     5701 acggtatgcg catcgtgatt gaagtgaaac gcgatgcggt cggtgaagtt gtgctcaaca
     5761 acctctactc ccagacccag ttgcaggttt ctttcggtat caacatggtg gcattgcacc
     5821 atggtcagcc gaagatcatg aacttgaaag acatcatcgc ggcgtttgtt cgtcaccgcc
     5881 gtgaagtggt gacccgtcgt actattttcg aactgcgtaa agctcgcgat cgtgctcata
     5941 tccttgaagc attagccgtg gcgctggcga acatcgaccc gatcatcgaa ctgatccgtc
     6001 atgcgccgac gcctgcagaa gcgaaaactg cgctggttgc taatccgtgg cagctgggca
     6061 acgttgccgc gatgctcgaa cgtgctggcg acgatgctgc gcgtccggaa tggctggagc
     6121 cagagttcgg cgtgcgtgat ggtctgtact acctgaccga acagcaagct caggcgattc
     6181 tggatctgcg tttgcagaaa ctgaccggcc ttgagcacga aaaactgctc gacgaataca
     6241 aagagctgct ggatcagatc gcggaactgt tgcgtattct tggtagcgcc gatcgtttga
     6301 tggaagtgat tcgtgaagag ctggagctgg ttcgtgaaca gttcggtgac aaacgtcgta
     6361 ctgaaatcac cgccaacagc gcagacatta acctggaaga tctgatcact caggaagatg
     6421 tggtagtgac gctctctcac cagggctacg ttaagtatca gccgctttct gaatacgaag
     6481 cgcagcgtcg tggcgggaaa ggtaaatctg ccgcacgtat taaagaagaa gactttatcg
     6541 accgactgct ggtggcgaac actcacgacc atattctgtg cttctccagc cgtggtcgcg
     6601 tctattcgat gaaagtttat cagttgccgg aagccactcg tggcgcgcgc ggtcgtccga
     6661 tcgtcaacct gctgccgctg gagcaggacg aacgtatcac tgcgatcctg ccagtgaccg
     6721 agtttgaaga aggcgtgaaa gtcttcatgg cgaccgctaa cggtaccgtg aagaaaactg
     6781 tcctcaccga gttcaaccgt ctgcgtaccg ccggtaaagt ggcgatcaaa ctggttgacg
     6841 gcgatgagct gatcggcgtt gacctgacca gcggcgaaga cgaagtaatg ctgttctccg
     6901 ctgaaggtaa agtggtgcgc tttaaagagt cttctgtccg tgcgatgggc tgcaacacca
     6961 ccggtgttcg cggtattcgc ttaggtgaag gcgataaagt cgtctctctg atcgtgcctc
     7021 gtggcgatgg cgcaatcctc accgcaacgc aaaacggtta cggtaaacgt accgcagtgg
     7081 cggaataccc aaccaagtcg cgtgcgacga aaggggttat ctccattaag gttactgaac
     7141 gtaatggttt agtggttggc gcggtacagg tagatgactg cgaccagatc atgatgatca
     7201 ccgatgccgg tacgctggta cgtactcgcg tttcggaaat cagcatcgta ggccgtaaca
     7261 cccagggcgt gatcctcatc cgtactgcgg aagatgaaaa cgtagtgggt ctgcaacgtg
     7321 ttgctgaacc ggttgacgag gaagatctgg ataccatcga tggcagtgcc gcggaagggg
     7381 acgatgaaat cgctccggaa gtggacgttg acgacgagcc agaagaagaa taattttact
     7441 tcttcatgcc aaaagggagc tatctccctt gtttgaattg aaaagtccag gctgcaaagt
     7501 ctgggctttt gtcgtattag ggcacggtaa agtttggctg tgcccgtaaa aaatggctgg
     7561 ctatacacaa ggaatgtggc aatgagtggt gaaaaaaagg cgaaaggctg gcggttctat
     7621 ggtcttgtag gttttggcgc aatagcactg ctttccgctg gcgtctgggc gttgcaatat
     7681 gctggcagtg ggccagaaaa aacgttgtcg ccgctggtgg tgcacaacaa tctgcaaatc
     7741 gatctcaatg agccggacct ctttctcgac agcgactctc tgagccagct tcccaaagat
     7801 ctcctcacca ttccgtttct ccacgatgtt ctgagcgaag atttcgtttt ctattatcag
     7861 aatcatgccg atcgtctggg cattgaaggc agcattcgtc gtattgtcta tgaacacgat
     7921 ctcacgctga aagataagct cttttcgtca ctcttagatc agcccgcgca ggcagcgctg
     7981 tggcacgata aacaaggcca tctttcacat tatatggtgc tgatccagcg cagtggttta
     8041 agcaaactgc tggagccatt gttgtttgcc gctaccagcg acagccagtt aagcaaaacg
     8101 gaaatcagta gcatcaagat aaatagtgaa actgttcctg tttatcagtt gcgctataac
     8161 ggcaataacg ccctgatgtt cgcgacttat cagaacaaga tgctggtgtt ttccagcacg
     8221 gatatgttgt ttaaagatga tcagcaggat accgaagcca cggcgatcgc aggtgatttg
     8281 ttgagcggca aaaaacgctg gcaagcaagc tttggcctgg aagagcgtgc tgctgaaaaa
     8341 acgccagtac gccagcgcat cgtggtcagc gccaggttgc tgggttttgg ctaccagcgg
     8401 ttaatgcctt cttttgctgg cgtacgcttc gaaatgggta acgacggctg gcacagtttt
     8461 gtggcgttaa atgatgaatc cgccagcgta gataccagtt tcgattttac gccggtctgg
     8521 aacagtatgc ctgccggggc cagcttctgt gtggtggtgc cgtattcaca cggtattgcc
     8581 gaagagatgc tttcgcacat cagtcaggaa aacgacaagt tgaatggggc gttagacggt
     8641 gccgcggggc tgtgctggta tgcagactca aaattgcaaa ccccgctgtt tgtcggtcag
     8701 tttgatggca ctgccgaaca ggcgcaattg ccagggaaac tgtttacgca aaatattggt
     8761 gcgcacgaaa gcaaagcgcc agaaggtgtt ttgccgataa gccagactca gcagggcgaa
     8821 gcgcaaatct ggcgtcgcga agtgagttcc cgatacggtc agtatccgaa agcgcaggcg
     8881 gcgcaacccg atcaattaat gtcggattat tttttccgcg tgtcgctggc gatgcaaaac
     8941 aaaacgctgc ttttctccct cgatgacacg ctggttaata acgccctgca aacactgaat
     9001 aaaaaccgcc cggcaatggt ggatgtaata cccactgatg gcatcgttcc gctctatatc
     9061 aatccacaag gcgtggcgaa actgctgcgt aacgaaacgt tgaccagtct gccgaagaat
     9121 ctcgaaccgg ttttttataa cgccgcacaa actttattaa tgccgaagct ggacgcttta
     9181 tctcaacaac cgcgttatgt catgaagctg gcccagatgg aacccggtgc cgcctggcag
     9241 tggctaccca taacctggca gccgctatga ggcacgggct gctggcgctg atttgctggc
     9301 tgtgttgtgt tgttgcccat agcgaaatgc tgaatgtcga acaatccggg ctgtttcgcg
     9361 cctggtttgt acgcattgca caagaacagc tccgccaggg gccaagtcca cgctggtatc
     9421 agcaggattg tgcgggcctg gtgcgatttg cggcgaacga gacgctgaaa gttcacgata
     9481 gtaaatggct aaaaagtaac ggtttctcta gccagtattt gccgccagag atgacgctaa
     9541 cacctggaca gcgtcaactg gcgcaaaact ggaatcaggg gaacgggaaa accggcccct
     9601 acgtgaccgc gattaatttg attcagtaca acagccagtt tattggccag gacataaacc
     9661 aggcgctgcc tggcgatatg atttttttcg atcagggcga tgcccagcac ttaatggtct
     9721 ggatggggcg ttacgtcatc taccacaccg gaagcgccac gaaaactgac aacggaatgc
     9781 gcgcagtcag tctgcaacaa cttatgacat ggaaggacac ccgatggata cccaacgatt
     9841 ccaatcccaa tttcattggc atttatcgtt taaattttct ggcgcgatag cagcgtgctt
     9901 gtccctgtct cttgtgggaa cagggcttgc taatgctgat gattcgcttc cttccagtaa
     9961 ctatgcgccg cccgccgggg gaacattctt tttgcttgct gacagcagtt ttagcagcag
    10021 tgaagaggcg aaagtgcgac tggaagcgcc ggggcgtgat tatcggcgct atcagatgga
    10081 agagtacggc ggcgtggacg ttcgcctgta tcgtattcct gacccgatgg catttttgcg
    10141 ccagcagaaa aacctgcatc gcattgtggt gcaaccgcaa tatctgggcg acgggctgaa
    10201 caatacgctg acctggctgt gggataactg gtacggcaaa tctcgccgcg taatgcagcg
    10261 tactttctct tctcagtcac ggcagaatgt gactcaggca ttacccgaat tacatctcgg
    10321 caatgccatt attaaacctt cccgttatgt acagaacaac cagttttccc cgctgaaaaa
    10381 atatcccttg gtggaacagt tccgttatcc actatggcag gctaaaccgg tcgagccgca
    10441 gcaaggggta aaactggaag gcgcatccag caatttcatc tcgccgcagc cgggtaacat
    10501 ttatattcct ctcggccaac aagagccggg actgtacctc gtcgaggcga tggttggtgg
    10561 gtatcgggcg acgacggtgg tgtttgtttc cgataccgtg gcgcttagca aagtgtcagg
    10621 caacgagctt ctggtgtgga ccgcgggtaa aaaacagggt gaagcgaagc ccggctcaga
    10681 gatcttgtgg actgacggtc ttggcgtgat gacccgcggt gtgaccgatg acagcggtac
    10741 cttgcagtta caacatatat cgccagaacg ttcatacatt ctgggtaagg atgctgaagg
    10801 cggcgttttt gtctccgaga acttctttta cgaaagtgaa atctacaaca cccgcttgta
    10861 tatctttacc gatcgcccgc tatatcgcgc aggcgatcgt gtcgatgtta aagtgatggg
    10921 ccgcgagttc cacgatccgt tgcattcatc ccccatcgtc agcgccccgg cgaagctttc
    10981 ggtgctggac gccaacggca gtctgttgca aatcgtcaat gtcacgctgg atgcgcgcaa
    11041 tggcgggcag ggaagtttcc gcctgccaga aaatgccgta gccggaggtt atgagttacg
    11101 tcttgcttac cgcaatcagg tctatagcag cagttttcgc gtggcaaact acatcaagcc
    11161 acatttcgag attggtttag ctctcgacaa aaaagagttc aaaactggcg aagcggtcag
    11221 cggcaaactg caactgcttt acccggatgg tgagccggta aaagatgccc gcgtgcagtt
    11281 aagtttgcgc gctcagcaat tatcaatggt cggtaacgat ttgcgttatg ccggacgttt
    11341 tcccgtgtcg ctggaaggca gcgaaacggt gtccgacgcc agcggtcatg tggcgttaaa
    11401 tctccccgcc gccgataaac cgagccgcta tttgttaacc gtctccgcca gtgacggcgc
    11461 ggcgtatcgt gtcaccacca ccaaagagat cctcattgaa cgcggtctgg cgcattactc
    11521 attaagtact gccgcacaat acagtaatag cggcgagtcg gttgtgttcc gttatgccgc
    11581 gctggaatct tcaaaacagg ttcctgttac gtatgaatgg ttgcgtctcg aagaccgcac
    11641 gagccatagc ggagagctac cgtcaggcgg caaatccttt accgtcaatt tcgctaaacc
    11701 tggcaactac aatctgacat tacgcgataa agacggctta attctcgctg ggttaagtta
    11761 tgccgtcagc ggtaagggca gcacggcgca tacgggtacg gtagatatcg tggcggataa
    11821 aacgctgtac cagccaggcg aaaccgcgaa gatgctgatt acctttccgg agccaattga
    11881 tgaagcatta ttgacgctgg aacgcgatcg cgtggaacag cagtcgctgc tttcgcatcc
    11941 ggcaaactgg ctaacgctac aacgtttaaa cgatacccag tatgaagccc gggttccagt
    12001 gagcaattcc tttgcgccta acatcacttt ttcggtgctg tatacccgta atggtcagta
    12061 cagttttcag aacgccggga tcaaagttgc cgttcctcag cttgatatcc gggtgaaaac
    12121 ggacaaaacc cattaccagc ctggtgaact ggtcaatgtc gaattaacct cgtcgctgaa
    12181 aggtaaacct gtttctgcgc agctaacggt aggcgtggtc gatgaaatga tctacgcgct
    12241 gcaaccagaa atcgcgccga atatcggcaa atttttctat ccgctggggc gtaacaatgt
    12301 gcgtaccagc tccagtctgt cgtttatcag ctacgaccag gcgctctcca gcgagccggt
    12361 tgcgcctggc gcaactaacc gcagcgagcg gcgagtaaaa atgcttgaac gtccacggcg
    12421 tgaagaggtg gataccgcgg catggatgcc gtcactcaca accgataaac aaggcaaagc
    12481 gtatttcacg ttcctgatgc ctgattcgtt aacccgctgg cgtatcaccg cgcgtgggat
    12541 gaacggcggc gggctggtcg ggcaggggcg tgcttatctg cgttcggaaa aaaatctcta
    12601 catgaagtgg agtatgccaa cggtgtatcg cgtgggcgac aaaccggcgg caggactgtt
    12661 tatcttcagt cagcaggata acgaaccggt ggcgctggtg acgaaatttg caggcgctga
    12721 gatgcgccag gcgctgacgc tgcacaaagg ggcgaattat atttcgctgg cgcagaacat
    12781 tcagcaatct ggcttgttaa gcgcagaact gcaacaaaat gggcaagtgc aggacagcat
    12841 tagcacaaaa ctgtcttttg tggataacag ctggcccgtt gaacagcaga aaaatgtcat
    12901 gctcggcggt ggcgagaacg cgctgatgtt gcccgagcag gctagcaata tccggctaca
    12961 aagtagcgaa acgccgcagg agattttccg caacaatctt gatgcgttag tcgatggacc
    13021 atggggtggc gtgatcaaca ccggtagccg tctgatcccg ctcagtctcg cctggcgttc
    13081 gcttgccgat catcaaagtg ccgccgctaa cgacattcgt cagatgattc aggataaccg
    13141 tctgcggctg atgcaactgg cggggcccgg agcgcgcttt acctggtggg gtgaagatgg
    13201 caatggtgac gccttcctta cggcatgggc atggtacgcc gactggcagg ccagccaggc
    13261 gatcggcgta acgcaacaac cggaatactg gcagcatatg ctcgacagct acgcggagca
    13321 ggcagataac atgccgttat tgcatcgggc gctggtgctg gcgtgggcac aggagatgaa
    13381 tctgccgtgc aaaacgttgt tgaaagggtt ggatgaagct atcgcccggc gcggaactaa
    13441 agatgaagat ttctctgagg aagacatccg cgatatcaat gacagcctga tcctcgatac
    13501 accggaatct ccactggcag atgcggtggc aaacgtctta accatgacgt tgctgaaaaa
    13561 agcgcagttg aagtccacgg tgatgccaca ggttcagcaa tatgcgtggg ataaagcggc
    13621 aaacagcaat cagccgctgg cgcacacggt tgtgctgctc aatagcggtg gtgacgctac
    13681 ccagacggcc gctattttaa gtggtttgac cgctgagcaa tccactattg agcgcgcgct
    13741 ggccatgaac tggctggcga aatatatggc gacaatgcct ccagttgttt tgcctgcgcc
    13801 tgcgggcgca tgggctaaac ataagttaac tggagggggc gaagactggc gttgggttgg
    13861 tcagggcgtg ccggacattc tctcttttgg tgacgaatta tcgccgcaaa atgtgcaggt
    13921 ccgctggcgt gagccggcaa aaatggctca acaaagtaac attccggtga ccgttgaacg
    13981 ccagttgtat cggcttatcc ctggtgaaga agagatgagc tttattctgc aaccggtgac
    14041 cagcaatgag attgacagcg atgcgctgta tctcgatgaa attacgctta ccagcgagca
    14101 ggatgcagtt ctgcgctatg gtcaggtgga agtaccgctc ccgccgggag ccgacgttga
    14161 gcgcacaaca tggggcattt cagtcaataa acccaacgcc gcgaaacagc aggggcaatt
    14221 gctggaaaaa gcgcgtaatg aaatgggcga actggcctat atggtgccgg tgaaagaact
    14281 gacgggaacg gtcactttcc gccatttgct gcgcttctcg caaaaagggc aattcgttct
    14341 gcctcctgct cgttatgtgc gttcctatgc acctgcgcag caaagtgttg cggcagggag
    14401 tgaatggacc gggatgcagg tgaaataagt gaactggcgc agaatcgtct ggctattggc
    14461 gttggttact ctgccaacgc ttgcggagga gacgccgtta caactggtgc tgcgcggtgc
    14521 gcagcacgat caactgtatc agctgtcgtc atcaggcgtg accaaagtct cagcattacc
    14581 tgactcgctc accacgccgt tagggagttt gtggaaactg tatgtttacg cctggctgga
    14641 ggatacccat caaccggagc agccctacca gtgtcgcgga aactccccgg aagaggttta
    14701 ttgttgtcag gctggggaga gcataacgcg cgataccgcg ctggtacgtt cctgtgggct
    14761 ctattttgcg ccgcagcggt tgcatattgg cgcagatgtg tgggggcaat actggcaaca
    14821 gcgtcaggca cctgcgtggt tagcgtctct tacaacgctg aagccagaaa cctcggtaac
    14881 ggttaaatcg ctgctcgatt cattagcgac gttacctgcg caaaacaaag ctcaggaagt
    14941 cttactggat gtggtgctgg acgaggcgaa aatcggtgtc gcatccatgc tcggtagtcg
    15001 ggtacgggtg aaaacctgga gctggtttgc cgatgataaa caggaaatcc gccagggtgg
    15061 ttttgctggc tggttaaccg atggtacacc gctgtgggtt actggcagtg gcaccagcaa
    15121 aacggtacta acccgttatg cgacggtgct taatcgggtt ttgccagtgc cgacgcaggt
    15181 tgccagtggg caatgtgtag aggtggagct gtttgcccgc tatccgctga agaaaatcac
    15241 agcggaaaag agtacgacgg cagtaaaacc cggcgtactt aatgggcgct atcgtgtgac
    15301 gtttactaat ggtaaccaca ttacgtttgt cagccacggt gagacgacct tactgagcga
    15361 aaagggcaaa ctgaaattgc agtcgcatct cgatcgtgaa gagtacgttg ccagagttct
    15421 ggatcgcgag gcgaaaagta cgccccctga ggcagcgaaa gccatgaccg tggcgattcg
    15481 cactttttta cagcaaaacg ccaatcagga aggcgattgc ctgaccatcc ccgacagcag
    15541 cgccacgcag cgtgtttctg cttcgccagc gaccacgggg gcgcgaacga tgaccgcctg
    15601 gacgcaggat ctcatctatg caggcgatcc ggttcattat catggcagtc gcgctaccga
    15661 agggacactt tcctggcggc aagccacggc ccaggcgggg cagggggagc gttacgacca
    15721 gatactcgcg tttgcttatc ccgacaacag ccttagccgc tggggagctc cacgctcaac
    15781 ctgccagtta ttacccaaag cgaaagcctg gctggcgaaa aaaatgccgc agtggcggcg
    15841 tatattacaa ggcgagacgg ggtacaacga accagacgtg tttgcggtct gtcgtttagt
    15901 ctcaggtttc ccctataccg atcggcagca gaaacggctg tttattcgta acttctttac
    15961 gcttcaggat cggctggatt taacccatga gtatctgcac ctggcctttg atggttatcc
    16021 caccgggctt gatgagaact atatcgaaac gctgacccga caattattaa tggactaatg
    16081 ctatgcgaaa gatttttctt ccgttgttac tggtggcact ttcgcctgtc gctcacagtg
    16141 aaggtgtgca ggaagtcgag attgacgcac cgctctctgg ctggcatccg gcagagggcg
    16201 aagatgccag tttttcacaa tcgatcaatt acccggcgtc gtccgtcaac atggcagatg
    16261 atcaaaatat ctcagcgcag atccgcggca aaataaagaa ttatgctgcg gcgggtaaag
    16321 ttcagcaggg ccggctggtg gtcaacggtg ccagtatgcc gcagagagtt gaatccgatg
    16381 gttcatttgc acgcccttat attttcactg aaggcagcaa cagcgtgcag gtcatcagcc
    16441 cggatgggca aagccgacaa aaaatgcagt tttactcaat gccgggtaca ggaacgattc
    16501 gtgcacgttt acggctagtt ctctcgtggg atacggacaa taccgatctc gatctccatg
    16561 ttgtcacgcc cgatggcgaa cacgcctggt acggtaacac cgtgctgaaa aacagtggtg
    16621 cactggatat ggatgtcacg acggggtacg gacccgagat tttcgccatg ccagcaccag
    16681 ttcacgggcg ctatcaggtg tatatcaact actatggtgg gcgcagcgaa acggaattga
    16741 cgaccgccca actgacgctg atcaccgatg aaggatcggt caatgagaaa caggaaacat
    16801 ttattgtacc gatgcgtaat gctggcgagc tgacgctggt gaaaagtttt gactggtgat
    16861 ccatcccttc acacaacctg gctctctctt ttttcagata agactgctgg gcgatctgcc
    16921 gacgccagga tataaccatt aacaagcgtc ggcagattgg tcatttctta tttttcgtac
    16981 tgagaactgt ccatctactc cggctttcct ggttaaggca atggtttcta agcgatacgc
    17041 attattgcaa tggtgacaga acattgcggt aacacgcttt taccgctacc ttaaccacac
    17101 tccatcggtc acctgaggcg gagcttcgcc cctttgaaat accttgcttc ttttcgtaca
    17161 accctgaaag cctcgcgcta catgttcaga gcattggcgt tagtgctctg gctgttgatt
    17221 gctttttcat ccgtttttta catcgttaat gcgttacatc agcgagaatc ggaaattcgt
    17281 caggaattta atctgagttc cgatcaggct cagcgcttta ttcaacgcac ctctgatgtg
    17341 atgaaagagc tgaagtacat cgccgaaaat cgcttatcgg cagaaaacgg tgtgctttcc
    17401 ccgcgtggac gagaaacgca ggcggatgtg cctgcgtttg aaccgctgtt tgccgactcc
    17461 gattgttccg caatgagtaa cacctggcga ggttctctgg agtcattggc gtggtttatg
    17521 cgctactggc gcgataattt ttctgcggct tacgatctca accgggtatt tttaatcggc
    17581 agtgataacc tctgcatggc caatttcggt ctgcgtgata tgccagtgga acgcgatacc
    17641 gcgttgaaag ctttgcatga acgcatcaat aaatatcgaa atgcaccaca agatgatagc
    17701 ggcagtaacc tctactggat cagcgaaggt ccgcgccctg gcgtcgggta tttttacgcg
    17761 ttgacgccag tttatctggc gaaccggttg caggcgcttt tgggtgtcga gcagaccatc
    17821 cggatggaga actttttctt accgggtacg ttgccgatgg gggttaccat tcttgatgaa
    17881 aatggtcata ccctgatttc gcttaccgga ccagaaagta aaattaaggg cgatcctcgc
    17941 tggatgcagg aacgctcctg gtttggctat acggaagggt tccgggagct ggtgctgaag
    18001 aaaaatctgc caccctcatc gctaagcatc gtgtattcgg tgccggttga taaggtgctg
    18061 gaacgcattc gcatgttgat ccttaacgca attttgctga atgtgcttgc cggagctgca
    18121 ttgtttactc tcgcacggat gtacgagcga cgtattttca ttccggcgga aagcgacgcc
    18181 ctgcgactgg aagaacatga gcagttcaat cgcaagattg tcgcctccgc gccagtgggt
    18241 atctgcattt tgcgtaccgc tgatggcgtc aatattttaa gtaacgaact ggcgcatacc
    18301 tatctcaata tgcttacgca tgaggaccgc caacgactga cgcaaattat ctgtgggcag
    18361 caggtcaatt ttgttgatgt cctgaccagc aacaatacca atctgcaaat cagcttcgtc
    18421 cattcgcgct atcgtaatga aaacgtggcc atttgtgtgc tggtggatgt ttcttcgcgc
    18481 gtgaagatgg aagagtcgtt gcaggagatg gcacaagcag cggaacaggc gagccagtca
    18541 aaatcgatgt tccttgccac cgtcagtcat gagctgcgaa cgccgctgta tggcattatc
    18601 ggtaacctgg atctgttgca aaccaaagag ttaccgaaag gcgtcgatcg gctggtgacg
    18661 gcaatgaaca actcttccag cctgttgttg aaaattatca gcgatattct cgatttctcg
    18721 aagattgaat cggaacagtt gaagatcgaa ccgcgtgagt tttcaccgcg tgaagtgatg
    18781 aaccacatca ccgccaacta tttaccgctg gtggtacgca agcagttagg cttgtactgc
    18841 tttattgaac cggatgtgcc agtggcctta aatggcgacc cgatgcgttt acagcaggtc
    18901 atctccaacc tgttgagtaa cgccataaaa ttcaccgata ccggctgtat agttttgcat
    18961 gtccgcgctg atggcgatta tctctctatc cgtgttcgcg ataccggcgt ggggattccg
    19021 gcgaaagaag tggtgcgctt gtttgatccc ttcttccagg tcggaacggg cgtacagcga
    19081 aacttccagg ggaccggtct gggtctggcg atttgtgaaa aactgatcag catgatggac
    19141 ggcgatatct cggtagattc agaaccggga atgggcagcc agtttaccgt gcgtattccg
    19201 ttgtacggcg ctcagtaccc gcagaaaaaa ggcgtggaag ggttgagtgg taaacgctgc
    19261 tggctggcgg tccgcaatgc gtcgctctgt cagttcctgg aaaccagttt gcagcgcagc
    19321 ggcatcgtcg ttacaacata cgaagggcag gaaccgactc ccgaagatgt gttaattact
    19381 gacgaggtag tgagtaaaaa atggcagggt agagcggtag tgaccttctg tcgtcgccat
    19441 attggtattc cgctggagaa agcgccaggg gagtgggtac acagtgtggc tgccccgcat
    19501 gagctaccgg cattgttggc gcgtatttat ttgatcgaga tggagagcga cgatcctgct
    19561 aacgctctgc cgtcgacgga caaagcggtc agcgataatg acgatatgat gattctggtc
    19621 gtggatgatc atccgattaa ccgacgtctg ctggcagatc agttgggatc gttgggctat
    19681 caatgtaaaa ccgcgaatga tggtgtcgat gcgcttaatg tacttagcaa gaatcatatt
    19741 gatatcgtgc ttagcgacgt caacatgcca aatatggatg gttaccgctt gacgcaacgc
    19801 attcgtcagt tgggactgac gttgccggta atcggagtaa ctgctaatgc gttggctgaa
    19861 gagaagcagc ggtgtctgga gtccggtatg gacagctgcc tgtcgaagcc ggtaacgctg
    19921 gatgtgataa aacagacgct gacggtatat gccgagaggg tcaggaaatc gcgggaatcg
    19981 taggacggat aaggtgttta tgtcgcatct ggcattcagt gcaaatgcca gatgcgacgc
    20041 tgacgcgtct tatctggcct actttaatgt aatctgttga aataatggga atcgtaggcc
    20101 ggataaggcg tttacgccgc atccggcatt cagtgcaaat gccagataag acactaacgc
    20161 gtcttatctg gcctacaggt gattagtctt tatctgccgg acttaacgtc acagaagaga
    20221 gataattcag cagggcgata tcgttctcga cacccagctt catcatcgca gatttcttct
    20281 ggctactgat ggttttaata ctgcggttca gctttttagc gatctcggtc accaggaagc
    20341 cttccgcaaa caggcgcaga acttcactct cttttggcga gagacgcttg tcaccgtaac
    20401 caccagcact gattttttcc aacaggcgag aaacgctttc cggggtaaat ttcttccctt
    20461 tctgcagcgc ggcgagagct ttcggcagat cggtcggtgc accttgtttc agcacgatcc
    20521 cttcgatatc cagatccaat accgcactaa gaatcgccgg gttgttgttc atggtcagaa
    20581 caataatcga caggcttggg aaatggcgct tgatgtactt gattaaggta atgccatcgc
    20641 cgtacttatc gccaggcatg gagagatcgg taatcaacac atgcgcatcc agtttcggca
    20701 ggttgttgat cagtgctgta gagtcttcaa attcgccgac aacattcacc cactcaattt
    20761 gctcaagtga tttgcgaata ccgaacaaga ctatcggatg gtcatcggca ataattacgt
    20821 tcatattgtt catgtaatag gctaccttgc tacagcaagc tcttgacata actgtcaatg
    20881 tcgctgatgt atttttctat tcctggaaca tccttctcac gaatcagatg ttccagcgtt
    20941 tcacataact gcttgccggg taccagattt agcatggcaa atacgccttt aagacgatga
    21001 gccgtttggg ctaacgcagc aaagtcactg gttgctgctt cagtatacag cctcttaaca
    21061 tcatccggta ctgtgtctac aaagagcgca taatagccgc tggcatggag ttgcgcattt
    21121 tcatctccgc ccagaggcga ttctgtcacc tcttcctgcg ccagttgcac ttcaattaat
    21181 tgtaagaccg cttcctgcat agcgttgctc atattgaagt tgacgcacaa ttgaccaggc
    21241 ccaatttccc gtacgccaga ctcatcatcg cttaaaagca agccagaggc agtaagatta
    21301 gacggattat ccgttaaaaa gatatcataa tcttgactaa ttaatctttc atcgggtgtg
    21361 atacaggttg caccccaatt ttctaactgg cgagtgacaa tattccgaat ttctgccgaa
    21421 gtaacatcca ccattacgca gacatcatcc agtaaacgct cttcttcctc ttcaacttcc
    21481 gggtcagcgg cgagcatttt gatatgcaca gagtagcgtg taccaagccc atcccgcgtt
    21541 ttgatgttta aatgaccgcc cagtttacgc gccagttgat cgctcagcca gaatgccagc
    21601 gggtccgcct tgccatagcg atcgttttgg gtctggttga taaacgggaa gtgcaaatta
    21661 tccatttcat gaatacttac gccttctccg gtgtccagaa tgcggaatgt caggcggtct
    21721 tcagaggact catcctgatc aacctcaagg gtgatttttc ccaattgcgt tgaggtcacg
    21781 gcatattgca tcagtagcag caaaatacgt cgtaaggcat cgcgatcgcc gcggcgcata
    21841 tcgtgtgctt tcagatgatt gttaatcagc agttgcagac ctttacgctt gatggcaggc
    21901 aacactgaag gcacaacttc atcaattaaa tcctgcacgg agaacagcac cgtctcactt
    21961 ttccagctat catccgcaag catgttcgct aactgtattt catcaaccag ccgcaccagc
    22021 acatctgcct gattcgccag ttgtttgctt tccggggcgt tgagtttagc cgcgctctcc
    22081 gccagggact gtgcaggttc tttcagcgca tcgccaatgt ttttcataaa ggtcatccgg
    22141 ccctgctggt ttttctcata cagacgctgc gcctgcttga gtttcttgtt taccagcact
    22201 tcgcgatcct gatcgcgaat aatgaaaatt tgtgtgcgcg gcgcgacctg gctgcggaac
    22261 atgcggatct catacagctc gttattgatc gtcgcctgaa taatcccctg atgctgttcc
    22321 gccatggtgg tgatgttttg cagattcaaa tgcggcagca aatgatcggc aattttgtta
    22381 cttatgacag tgcggttcga ttcctgatcg tgaaccagca ggccgagcgg cagcagtgag
    22441 actatctctt cattaattgc ccgtaaaatg cgcaattcgt tattgaccgc cgtgctgggt
    22501 agactttctg tactgcggct ggagaaatgg cggaatgtgg tatagccaaa taacgccagc
    22561 gccagcaaac cgatgttcag cagcagtggc agcagaatgt tttgcaacgt atccagcaat
    22621 aaggtgccat aaggaacctg ccagaccagg cgcatatcgg tagagttgag tgccgaggag
    22681 atttcaatct tcgtactgtt aaagtggata ctgacgctat ccgtcccttc tttctcatta
    22741 tcattgtttc ccgttgccgt cgcgtctggc tcaaggcgga aactgtccag cggcataccc
    22801 ggtgggatca aatcattaat cggcagatca aaagccacga ccgttgccag atgtcctggc
    22861 tggttaaagg tagtacgcaa ggtaaagtaa tgaccgttct gccaggccag gcggcgcatg
    22921 ttagaaaagc tttcgcgttc atcgagggcg ttggcctgtt gcaacatctc tgcacgacgt
    22981 gaatcaacaa tgtcgctgac ggtcgattct ttaaatccgg aggtgagatc tttaaggggt
    23041 agggttgaga tcagcaccag actgttatcc tgaccattca ggtaatacat cgaccacggt
    23101 acattttctg cgccccacaa tgtatccaga taagtggaca tccgctgagt catctcaagc
    23161 gttgagttgt cgtgagagcc aaagattaac gcttccgttt tgcggcgtgg tttctccaga
    23221 tagtagacat cctgtttcag gcgcgtctct tgtaaacctt cgccggagga gggggaggtc
    23281 gtcgcggcaa tgttgtcgta gatctgccag gtcacgtaac gccagttatc gacgcgcttt
    23341 tggatagcat gggtaatgtc gacaatctgg taacttttat ctttcagcca ggcgttaacg
    23401 gcgctttgta ccattacacc catcgtcacc agtaacacaa tgatcaacag taaaaagaag
    23461 cgggtaatgc tccccggtag gagtgaaaag cgggtcgtgg ccgttgtctc tttctgacgc
    23521 attcgtgttt atgacctgtt aaaacttcgc gaagtgatag ggcagtataa agggtacagt
    23581 gtgaaattcc agactcttac ctgattgatg attctctatt ctcccgtgat atttatcatc
    23641 ctgcattggg ggaaatagat gtacaagcgc cattttgctg tacaaataac ctacaaaaag
    23701 cccaacaaaa ataattgcaa ataaacaaag attgctggaa attatgcgga tgttaattat
    23761 ttgtgaaata gttaacaagc gttatagttt ttctgtggta gcacagaata atgaaaagtg
    23821 tgtaaagaag ggtaaaaaaa accgaatgcg aggcatccgg ttgaaatagg ggtaaacaga
    23881 cattcagaaa tgaatgacgg taataaataa agttaatgat gatagcggga gttattctag
    23941 ttgcgagtga aggttttgtt ttgacattca gtgctgtcaa atacttaaga ataagttatt
    24001 gattttaacc ttgaattatt attgcttgat gttaggtgct tatttcgcca ttccgcaata
    24061 atcttaaaaa gttcccttgc atttacattt tgaaacatct atagcgataa atgaaacatc
    24121 ttaaaagttt tagtatcata ttcgtgttgg attattctgc atttttgggg agaatggact
    24181 tgccgactga ttaatgaggg ttaatcagta tgcagtggca taaaaaagca aataaaggca
    24241 tataacagag ggttaataac atgaaagtta aagtactgtc cctcctggtc ccagctctgc
    24301 tggtagcagg cgcagcaaac gctgctgaag tttacaacaa agacggcaac aaattagatc
    24361 tgtacggtaa agtagacggc ctgcactatt tctctgacaa caaagatgta gatggcgacc
    24421 agacctacat gcgtcttggc ttcaaaggtg aaactcaggt tactgaccag ctgaccggtt
    24481 acggccagtg ggaatatcag atccagggca acagcgctga aaacgaaaac aactcctgga
    24541 cccgtgtggc attcgcaggt ctgaaattcc aggatgtagg ttctttcgac tacggtcgta
    24601 actacggcgt tgtttacgac gtaacttcct ggaccgacgt actgccagaa ttcggtggcg
    24661 acacttacgg ttctgacaac ttcatgcagc agcgtggtaa cggtttcgcg acctaccgta
    24721 acactgactt cttcggtctg gttgacggcc tgaactttgc tgttcagtac cagggcaaaa
    24781 acggtagcgt aagcggcgaa ggcatgacta acaacggtcg tgaagcactg cgtcagaacg
    24841 gcgacggcgt tggcggatct atcacttatg attacgaagg cttcggtatc ggtgctgcag
    24901 tttccagctc caaacgtact gatgatcaga acagcccgct gtacatcggt aacggcgacc
    24961 gtgctgaaac ctacactggt ggtctgaaat acgacgctaa caacatctac ctggctgctc
    25021 agtacaccca gacctacaac gcaactcgcg taggttccct gggttgggcg aacaaagcac
    25081 agaacttcga agctgttgct cagtaccagt tcgactttgg tctgcgtccg tccctggctt
    25141 acctgcagtc taaaggtaaa aacctgggtc gtggctacga cgacgaagat atcctgaaat
    25201 atgttgatgt tggtgcgacc tactacttca acaaaaacat gtccacctat gttgactaca
    25261 aaatcaacct gctggacgac aaccagttca ctcgtgacgc tggcatcaac actgataaca
    25321 tcgtagctct gggtctggtt taccagttct aatctcgatt gatatcgaac aaagggcctg
    25381 cgggcccttt tttcattgtt ttcagcgtac aaacacagtt ttttggtgta ctcttgcgac
    25441 cgttcgcatg aggataatca cgtatggaaa taagctttac ccgcgtggca ctgctggctg
    25501 ccgcgctctt ctttgttggt tgcgatcaaa aaccacaaac cgccaaaacc cacgctactg
    25561 aagttaccgt tcttgaaggc aaaactatgg gtaccttctg gcgtgccagc atcccgggca
    25621 ttgacgccaa acgcagtgcc gaacttaaag aaaagattca gacccagctg gacgccgacg
    25681 atcagctgct ttcgacctat aaaaaagatt ccgcgctgat gcgctttaac gattcgcaaa
    25741 gtttatcgcc gtggccggta agtgaagcga tggccgatat cgtcaccacc tcgctgcgca
    25801 ttggcgcaag gaccgatggt gcgatggata taaccgtcgg gccgctggtg aatctgtggg
    25861 gctttggccc ggaacaacag ccggttcaaa ttccgagcca ggaacagatc gatgcgatga
    25921 aagccaaaac cggcttacag cacctgacgg tcattaatca gtcgcatcag caatatctgc
    25981 aaaaagacct accggattta tatgtcgatc tctccaccgt cggtgaaggt tatgcggcgg
    26041 atcacctggc acgcttgatg gagcaggaag ggatttcccg ctatctggtg tcggtgggcg
    26101 gcgcgctgaa cagccgtggt atgaacggtg aaggcctgcc gtggcgggta gcgattcaaa
    26161 aaccaaccga taaagaaaac gcggttcagg ctgtggtgga tatcaacggt catggtatta
    26221 gcacctctgg cagttaccgt aactattacg aactggacgg caaacgtctt tctcatgtta
    26281 tcgatccgca aaccgggcgt cccatcgaac acaatctggt atccgtgacg gtgattgctc
    26341 cgacggcgct ggaagccgat gcctgggata ctggcttgat ggtactcggg ccggagaaag
    26401 ccaaagaggt tgttcgccgg gaagggctgg cggtttatat gatcaccaaa gaaggcgata
    26461 gctttaaaac ctggatgtca ccacagttta aaagcttcct tgtcagcgaa aaaaattaaa
    26521 gcgcaagatt gctggttttt gcgtgatggt gaccgggcag actaaaggct atccttaacc
    26581 agggagctga ttatgaaaaa cgccacatgc ttaactgacg atcaacgctg gcaatctgtc
    26641 ttagcccgcg acccgaatgc cgacagcgaa ttcgttttcg ccgtgcgcac cacaggcatc
    26701 ttttgccgtc cgtcttgccg cgccagacat gccttgcggg aaaatgtctc cttctacgca
    26761 aatgcctgcg aggcactcgc cgccggattt cgcccctgca aacgctgcca acctgataaa
    26821 gccaatgccc agcaacatcg gttggataaa atcacccacg cgtgtcgact gctggaacag
    26881 gaaacgcctg taacgttgga agccttagcc gatcaggtgg cgatgagtcc gttccatctg
    26941 catcggttgt ttaaagcgac taccggaatg acgcctaaag cctggcaaca ggcctggcgc
    27001 gctcgccgtt tgcgcgaatc gctggcgaaa ggggagagcg tgacgacgtc tattcttaac
    27061 gccggattcc ccgacagcag cagttactac cgcaaagccg atgaaacgct gggcatgacg
    27121 gctaaacaat tccgtcacgg tggcgaaaat ctggcggtgc gttacgcgct ggctgattgt
    27181 gcgctggggc gttgcctggt ggcagaaagc gagcggggga tttgcgcgat attactgggc
    27241 gatgatgacg cgacactaat cagcgagttg cagcagatgt ttcccgctgc cgacaacgcg
    27301 cctgccgatc tgatgtttca gcaacatgtg cgtgaagtga tcgccagcct caatcaacgc
    27361 gatacgccgc tgacgttacc gctggacatt cgcggcactg cttttcagca acaagtctgg
    27421 caggcactgc gcacgatacc ttgcggtgaa accgtcagtt atcagcaact ggctaacgcc
    27481 atcggcaaac cgaaagcggt acgggccgtt gccagcgcct gtgccgccaa caagctggct
    27541 atcataatac cctgtcatcg ggtggtccgt ggtgatggca cactttccgg ttaccgctgg
    27601 ggcgtgtcgc gtaaagcgca actgctgcgc cgcgaagctg aaaatgagga gaggtaatgt
    27661 tggatctgtt tgccgatgct gaaccgtggc aagagccact ggcggctgga gcggtaattt
    27721 tgcaccgttt tgcttttaac gctgcggagc aactgatccg cgatattaat aacgttgcca
    27781 gccagtcgcc gtttcgccag atggtcaccc ccgggggata taccatgtcg gtggcgatga
    27841 ccaactgtgg gcatctgggc tggacgagcc atcggcaagg ttatctctat tcgcccattg
    27901 atccgcaaac aaataaaccg tggcccgcca tgccacagag ttttcataat ttatgtcaac
    27961 gtgcggctac ggcggcgggc tatccagatt tccagccaga tgcttgtctt atcaaccgct
    28021 acgctcctgg cgcgaaactg tcgctgcatc aggataaaga cgaaccggat ctgcgcgcgc
    28081 caattgtttc tgtttctctg ggcttacccg cgatttttca atttggtggc ctgaaacgta
    28141 atgatccgct caaacgtttg ttgttggaac atggcgatgt ggtggtatgg ggcggtgaat
    28201 cgcggctgtt ttatcacggt attcaaccgt tgaaagcggg gtttcatcca ctcaccaccg
    28261 actgccgcta caacctgaca ttccgtcagg caggtaaaaa agaataaaaa taagaattat
    28321 tattgctgtg cgcgcgaaga tgtttaaact gcgggctgta attcattgtc cgggttttct
    28381 gcatggaact tcttgtactt gtctggcggc agtatcgctg gccatttatc agtgtgatgg
    28441 cgctaagcct cgccagtgcg gcattaggca ttggcttaat tgcttttatc aatcagcgcc
    28501 ttatcgaaac ggcggatacc agtctgctgg tgttgccgga gtttcttgga ttattactgc
    28561 tgttgatggc agtcactctc ggatcgcaac tggcgctcac cactttgggg catcacttcg
    28621 tttaccgact gcgtagtgaa tttatcaagc ggattctgga tacccacgtc gagcgcattg
    28681 aacaactcgg tagcgcctcg ttgctggcgg gattaaccag cgatgtgcgc aatatcacca
    28741 ttgcttttgt gcgtcttccg gaactggtgc aggggatcat tctcactatc ggttccgcgg
    28801 cgtatctgtg gatgctgtcg ggcaaaatgt tgctggtaac ggctatctgg atggcgatca
    28861 ccatctgggg tggttttgta ctggtggcgc gggtgtacaa acatatggcg accctgcgtg
    28921 aaaccgaaga caagctgtac acggattttc aaaccgtact cgaagggcgc aaagagctga
    28981 ctctgaaccg ggaacgcgcc gagtatgtgt ttaacaacct ctacatcccc gatgcgcaag
    29041 agtatcgcca tcatattatc cgcgcagaca ccttccatct tagcgccgtg aactggtcaa
    29101 acatcatgat gctgggcgct atcggcctgg tgttctggat ggcgaacagt ctcggttggg
    29161 ctgataccaa cgttgctgcg acctattcgt tgacgctgtt attcctgcgt acgccgctgc
    29221 tttcggcggt tggcgcattg ccgacgctgc tgacggcgca ggtggcgttt aacaagctga
    29281 acaaattcgc gctcgcgcct ttcaaagctg agtttccgcg cccgcaggct tttcccaact
    29341 ggcaaacgct ggagctgcgt aacgtgacgt ttagctatca ggataacgcg ttttccgttg
    29401 ggccgattaa cctcaccatt aaacgtggcg agctgctgtt tctgattggt ggcaacggta
    29461 gtggaaaatc gacgctggcg atgttgctga cgggcttgta ccagccacaa agcggcgaaa
    29521 tcttgctgga tggcaaacct gtcagtggcg aacaaccgga agattatcgc aaactgtttt
    29581 cggcagtgtt taccgatgtc tggctgtttg atcaactgct ggggccggag ggtaaacccg
    29641 ctaacccgca actggttgag aagtggctgg cgcagctgaa aatggctcat aagcttgagt
    29701 taagcaacgg gcgtattgtt aacctgaagt tatcaaaagg gcagaaaaaa cgcgtggcgc
    29761 tgttgctggc gctggcagaa gaacgcgata ttatcctgct ggatgaatgg gcggcggatc
    29821 aggatccaca cttccgtcgt gagttttatc aggtgttgct gccgctgatg caggagatgg
    29881 gtaaaactat tttcgctatc agtcatgatg atcattactt tatccacgcc gaccgcctgc
    29941 tggaaatgcg caatgggcaa cttagcgagc tgacgggcga agagcgcgat gccgcttcgc
    30001 gtgatgccgt tgcccggacg gcataatatt acgacgctga cctggcggac tgctgccgtc
    30061 aggtcaatat gctaaaaatc ccttcatttc taataaccct ataattaatc aacgaaatta
    30121 taatgtttct aaaattagaa tataatttat aaacattatt taaatgttgt tacttaagtg
    30181 ttaccgttga tgccgcgcaa atctcacctg caataaagcg actaaaagta aggcattaac
    30241 aagatgaaaa aagtgactgc catgctcttc tcgatggccg tggggcttaa tgccgtttcg
    30301 atggcggcaa aagcgaaagc gtccgaggag caggaaactg atgtactgtt gattggcggc
    30361 ggcattatga gcgccacgtt ggggacctat ttacgcgagc tggagcctga atggtcgatg
    30421 accatggtgg agcgcctgga gggtgtcgcg caggagagtt cgaacggctg gaataacgcc
    30481 ggaaccgggc attctgcact gatggaactg aactacaccc cgcaaaacgc cgatggcagc
    30541 atcagtattg aaaaagcagt cgccattaac gaagcatttc agatttcccg ccagttctgg
    30601 gcgcaccagg ttgagcgcgg cgtgctgcgt actccgcgtt catttatcaa taccgttccg
    30661 catatgagct ttgtctgggg cgaggataac gttaatttcc tgcgcgcccg ttacgccgcg
    30721 ttgcaacaaa gctcgctgtt tcgcggtatg cgttactctg aagatcacgc gcagatcaaa
    30781 gagtgggcac cgttagtgat ggaagggcgc gatccgcaac agaaagtggc agccacgcgt
    30841 acggaaattg gtaccgatgt gaactacggc gagatcaccc gccagttaat tgcttccttg
    30901 cagaagaaat ctaacttctc gctgcaactc agcagcgaag tccgcgccct aaagcgtaat
    30961 gacgataaca cctggaccgt taccgttgcc gatctgaaaa acggcactgc acagaacatc
    31021 cgcgccaaat ttgtctttat cggcgcgggc ggtgcggcgc tgaagctatt acaggaatcg
    31081 gggattccgg aagcgaaaga ctacgccggt ttcccggtgg gcggacagtt ccttgtttcg
    31141 gaaaacccgg acgtggttaa tcaccatctg gcgaaggttt acggtaaagc atccgttggc
    31201 gcaccaccga tgtcggttcc gcatatcgat acccgcgttc tggacggtaa acgcgtagtg
    31261 ctgtttgggc catttgccac cttctcaacc aaattcctca aaaacggttc attgtgggat
    31321 ctgatgagtt ccaccaccac ctctaacgtg atgccgatga tgcacgtcgg gctggataat
    31381 ttcgatctgg tgaaatatct ggtgagtcag gtgatgttga gtgaagagga tcgttttgaa
    31441 gcgttgaaag agtactatcc gcaggcaaaa aaagaggact ggcgtttgtg gcaagcgggg
    31501 cagcgcgtgc agattatcaa gcgtgatgcc gagaaaggtg gcgtactgcg tctgggtact
    31561 gaagtggtca gtgaccagca agggaccatt gccgcgctgc tgggggcatc gccaggggcg
    31621 tcaaccgccg cgccgattat gttggatctg ctggaaaaag tatttggcga tcgcgtttcc
    31681 agcccgcaat ggcaggctac gttgaaagcg atcgttccgt cttatggacg caagctgaac
    31741 ggtgatgtag cggcaacaga acgcgagttg cagtacacca gcgaagtgct ggggctgaaa
    31801 tacgacaagc cgcaggcagc agatagtacg ccaaaaccgc agttgaaacc gcaacccgtt
    31861 caaaaagaag tggcggatat tgcgttgtaa tgatgtgcca catccggcat ggtatgccgg
    31921 atgtggcgta tgctgataag acgcgccagc gtcgcatcag gcaccggctc gggcgttaga
    31981 tgtcggatgc ggcgtgaccg ccttattcgg cctacggggt gccgcacttc acagcatttt
    32041 agcgaactac cgcgttgtca attttctctt ccgccttcca gacgcggtac ttcacatcta
    32101 cattgtctgg cgtatacacc acgatcggca gcttgctgtt gtaacgcagc attccagcat
    32161 cgcccagata cgcggtgaca aatttcttct ctttcttgcc atccgggcag gccatcatcg
    32221 tggaaaccgg cgagctaact ttatcaaaga cataataatc atagccccag ccttccagcg
    32281 ttttgctttc cagcttcccg ccgagacgat gcaaattgca atcgacttcc agcgtctgac
    32341 cgattaacag ttctactttc agggtagatt catcttcttg cggggttaac tgaatcacct
    32401 gacgcttcat ccctttttca gcttgtggat aaggcgcgat tttttccagt ggctggacgc
    32461 tttctgccgc ccaggcggaa gtggtagcga aagcggcaaa caatactgca ggtagaatgg
    32521 tcttcatttt tttgctttcc ttcttcattt ataggttttc accgatgatg tcgctgaagg
    32581 ttaacatatt catcagattt attaatttgc tttatgaata acttaaagaa cattcagaca
    32641 attttacctg ctcttttagt gttaaattct gatgagggag caaaccagca gaaatatctc
    32701 tggtgaatta atcgctatat aaatatgttt ataaccattt gaaatgtgag caaaagcccg
    32761 tttttgccac gcttcccgcc actcttttga tcctgctaca ggttttaccc cgatcggggt
    32821 atgcatcttt gacacatcct ttaatatctt agcggctata aaaatggctt attaattatg
    32881 cggtttattt ggtcgctctc aattttcaga gcgcgttaat gatggaaggt caatgtgaag
    32941 attgatgcat cccgtcgggg catactcact ggtcgctggc gcaaagccag taacggtatc
    33001 cgtccaccct ggtccggtga tgaatctcat tttctgaccc attgcacccg ttgcgacgcc
    33061 tgtattaatg cttgtgaaaa caacattctg caacgcggcg cgggcggcta tccgagcgtt
    33121 aatttcaaaa ataacgagtg cagcttctgt tacgcctgcg cgcaggcttg ccccgaatcg
    33181 ctattttctc cgcgccacac cagggcctgg gatttgcagt tcaccattgg ggacgcgtgc
    33241 ctggcgtatc agtcagttga atgccgccgc tgtcaggata gctgtgagcc aatggcaatt
    33301 atctttcgcc cgacgctctc cggaatctac cagccgcaac ttaatagcca actttgcaac
    33361 ggatgtggag catgtgcagc cagctgtccg gtatcagcca taactgcgga gtatctccat
    33421 gcacactaac tggcaagttt gcagcctggt cgtgcaggcc aaaagcgaac gaatttcaga
    33481 catcagcacc caactgaacg cctttcccgg ctgtgaagtt gctgtcagcg acgcgccgag
    33541 cggtcagttg attgtggtgg tggaagcaga agacagcgaa acgctgatcc aaaccattga
    33601 gtcagtacgc aacgtagagg gcgtgctggc ggtgtcgctg gtttatcacc agcaggaaga
    33661 gcaaggtgag gaaacaccat gaaactcagt cgtcgtagct ttatgaaagc taacgccgtt
    33721 gcggccgctg cggcggctgc cggtctcagc gtgccgggcg ttgcccgcgc cgttgttggt
    33781 cagcaggaag ccattaaatg ggataaagcg ccgtgccgtt tctgcggtac tggttgcggc
    33841 gttctggtcg gaacgcagca ggggcgtgtg gtggcctgtc agggcgaccc ggacgcaccg
    33901 gttaaccgtg gcctgaactg cattaagggc tatttcctgc ccaagatcat gtacggtaaa
    33961 gaccgtttga cgcagccgct gctgcgtatg aaaaacggta aatatgacaa agaaggcgaa
    34021 tttaccccaa tcacctggga tcaggccttc gatgtgatgg aagagaaatt caaaaccgcc
    34081 ctgaaagaaa aaggaccgga atcgatcggt atgttcggtt ctggtcagtg gactatctgg
    34141 gaaggttatg ccgcgtccaa gctgttcaaa gcgggcttcc gttcgaacaa catcgacccg
    34201 aacgcacgtc actgtatggc gtcggcagta gttggcttta tgcgtacctt tggtatggat
    34261 gagccgatgg gctgctatga cgacatcgag caggctgacg cgtttgtgct gtggggcgct
    34321 aacatggcgg agatgcaccc gatcctctgg tcacgcatca ctaaccgtcg tctctctaac
    34381 cagaacgtca ccgtggcggt gctttctacc taccagcatc gtagcttcga gctggcggat
    34441 aacggcatca tctttacgcc gcaatctgac ctggtgatcc tgaactacat cgccaactat
    34501 atcattcaaa acaatgcgat aaatcaggac ttcttcagca agcacgttaa cctgcgcaaa
    34561 ggggcgacgg acatcggcta cggtttacgt ccgacccatc cgctggaaaa agcagcgaag
    34621 aatccgggtt ctgacgcctc cgaaccgatg agctttgaag attacaaagc cttcgttgct
    34681 gagtatacgc tggaaaaaac cgctgaaatg accggcgtgc cgaaagacca gttagaacaa
    34741 ctggcgcagc tgtatgccga tccgaacaag aaagtcatct cctactggac gatgggcttc
    34801 aaccagcata cccgtggtgt gtgggccaac aacctggtct acaacctgca cctgctgacc
    34861 ggcaaaattt cccagccggg ttgcggtccg ttctccctga ccgggcaacc ttctgcgtgt
    34921 ggtactgcgc gtgaagtggg cacctttgct caccgtctgc ctgcggacat ggtggtgact
    34981 aacgagaaac accgtgatat ctgtgagaag aagtggaata tcccgagcgg caccattccg
    35041 gcgaaaatcg gtctgcacgc ggtggcacaa gaccgtgcgc tgaaagacgg caagctgaat
    35101 gtttactgga ccatgtgtac caacaacatg caggccgggc cgaacatcaa tgaagagcgt
    35161 atgccgggct ggcgcgatcc gcgcaacttc atcatcgtct ccgatccgta tccgacagtc
    35221 agtgcgctgg ccgccgactt gatcctgccg accgcaatgt gggtagagaa agagggcgct
    35281 tacggtaacg ccgaacgccg tactcagttc tggcgtcagc aggtacaggc gccaggcgaa
    35341 gcgaaatcgg atctctggca gttagtccag ttctcccgcc gcttcaaaac tgaagaagta
    35401 tggccggaag agctgctggc gaagaaaccg gaactgcgtg gcaaaacgct gtacgaagtt
    35461 ctgtatgcca cccccgaagt gagcaaattc ccggtatccg aactggcgga agatcagctg
    35521 aacgatgaat cccgcgagct gggcttctat ctgcaaaaag ggctgttcga agagtacgca
    35581 tggtttggtc gcggtcacgg tcacgatctc gcgccgttcg atgactacca caaagcgcgc
    35641 ggtctgcgct ggccggtggt gaacggtaaa gaaacacagt ggcgttacag cgaaggtaac
    35701 gacccgtacg tgaaagcggg cgaaggctat aagttctacg gtaaaccgga tggcaaagcg
    35761 gtgatcttcg cactgccgtt cgaaccggcg gcggaagcac cggatgaaga gtacgacctg
    35821 tggctctcta ccggacgcgt tctggagcac tggcacaccg gcagtatgac tcgccgtgtg
    35881 ccggaactgc accgcgcctt cccggaagcg gtcttgttta ttcacccgct ggatgcgaaa
    35941 gcgcgcgatc tgcgccgtgg cgacaaagtg aaagtggttt ctcgccgtgg cgaagtgatc
    36001 tcgattgttg aaacgcgcgg tcgtaaccgt ccgccacagg gcctggtgta catgccgttc
    36061 ttcgacgccg cacagctggt taacaaactg acgctggatg cgaccgatcc gctctcgaaa
    36121 gagacggact tcaagaagtg cgcagtcaaa ctggagaagg tgtaagccat tatgtcccgg
    36181 tcagcgaaac ctcaaaatgg tcgccgccgc tttctgcgcg atgtcgttcg cacagcaggc
    36241 gggctggctg ccgtgggtgt ggcgctgggg ttacaacagc aaaccgcacg cgcatctggc
    36301 gtgcggttgc gcccgcccgg agccataaac gagaacgcct ttgccagtgc ctgtgtgcgt
    36361 tgcggtcagt gtgttcaggc ttgcccttac gacaccttaa aactggcgac gctggcctct
    36421 ggtctgtcgg cgggcacgcc atattttgtc gcacgggata ttccttgcga aatgtgtgag
    36481 gacattccgt gcgccaaagt gtgcccaagc ggtgcgctgg atcgtgagat tgaatcgatc
    36541 gacgacgcgc ggatggggct ggcggtactg gtggaccagg aaaactgtct caactttcag
    36601 gggctgcgct gcgatgtttg ttatcgcgaa tgcccgaaaa ttgatgaggc catcaccctg
    36661 gagctggagc gcaacacgcg taccggtaag cacgcccgct ttctgccgac ggttcacagc
    36721 gacgcctgta ccggttgcgg taagtgcgaa aaagtatgcg tgctggaaca accggcaatc
    36781 aaggtgttac cgctgtcact ggcgaaaggg gagttaggtc accattaccg cttcggttgg
    36841 ctggagggga acaatggcaa atcgtaaacg tgacgccggg cgcgaggcgc tggagaaaaa
    36901 aggctggtgg cgcagtcacc gttggctggt gttacgtcgc ctttgtcagt tcttcgtgct
    36961 ggggatgttt ttgagcggtc cgtggtttgg tgtgtggatc ttacacggta actacagcag
    37021 tagcctgtta ttcgacaccg ttccgctgac cgatccgctg atgacgctgc aaagtcttgc
    37081 cagtggtcat ctgcctgcca cggtggcgtt gaccggtgcg gtgattatca ccgtgctcta
    37141 cgccctggcg ggaaagcgat tattttgcag ctgggtctgc ccgctgaacc cgattaccga
    37201 cttagcgaac tggttacgca ggcgctttga cctcaatcag tctgcgacga tccctcgcca
    37261 cattcgctac gtgctgttgg tggtcattct gctgggatcg gccttaactg gcacgctcat
    37321 ctgggaatgg atcaaccccg tatctctgat ggggcgcagc ctggtaatgg gcttcggcag
    37381 cggcgcgctg cttattctcg cgctgttttt atttgatcta ctggtcgttg aacacggctg
    37441 gtgcgggcac atttgtccgg ttggcgcgct gtatggcgtg ctgggtagca aaggtgtgat
    37501 taccgttgcg gccaccgatc ggcagaaatg taaccgctgt atggattgtt ttcatgtttg
    37561 cccggaaccg catgtgctac gtgccccggt gctggatgaa caaagcccgg tgcaggtcac
    37621 cagccgcgat tgcatgacgt gcggtcgctg cgtggatgtc tgttctgagg atgtatttac
    37681 aataactaca cgatggagtt cgggagcgaa atcatgaaaa gccatgacct gaagaaagcg
    37741 ctgtgtcaat ggacggcgat gctggccctg gtggtaagcg gcgcggtttg ggcggctaat
    37801 ggcgtcgatt ttagccagtc gccggaagta tccgggacac aggaaggggc cattcggatg
    37861 ccaaaagagc aggaacggat gccgctgaac tatgtgaatc agccgccaat gatcccgcat
    37921 agcgttgaag gttatcaggt aacgaccaat accaaccgct gcttgcagtg ccacggtgtc
    37981 gaaagttatc gcaccactgg cgcgccgcgt atcagtccta ctcactttat ggacagcgac
    38041 ggcaaagtgg gcgcggaagt ggctccgcgt cgttatttct gtctgcaatg tcacgtaccg
    38101 caggccgata ccgcgccaat cgtggggaat acctttaccc catcaaaagg ttacgggaaa
    38161 taagaggtta ttatgggaaa ttctgaccgt aagcctggtc tgattaagcg cctgtggaaa
    38221 tggtggcgta cccccagccg tctggcgctg gggacgctgc tgttgatcgg ttttgttggc
    38281 ggcatcgtct tctggggtgg ctttaacacc gggatggaaa aagccaatac cgaagagttc
    38341 tgcattagct gccacgaaat gcgcaacacg gtgtatcagg aatacatgga ttccgtgcac
    38401 tacaacaacc gtagcggcgt ccgtgcgacc tgtccggatt gtcacgttcc gcacgagttt
    38461 gtgccgaaga tgatacgcaa gctcaaagca agtaaagagc tgtatggtaa aatttttggc
    38521 gttattgaca cgccgcagaa atttgaagct catcgtctga cgatggcaca gaatgagtgg
    38581 cggcgcatga aggacaataa ctcgcaggag tgccgtaact gtcacaactt cgagtatatg
    38641 gatacaaccg cccagaaatc ggttgccgcg aagatgcatg accaggcggt gaaagatggg
    38701 caaacctgta ttgattgcca taaagggata gcgcacaagc tgcccgatat gcgtgaagtc
    38761 gagccaggtt tttaacaggg ttattgcgtg ggtatgcttg aagccagaga gttactttgt
    38821 gagcgggatg aacgaacctt atttagtggc ttgtcattta cgctgaacgc aggagagtgg
    38881 gtacaaatca ccggtagcaa cggcgcgggg aagacaacgc ttctccgttt gctgactggg
    38941 ttgtctcgcc ctgacgctgg cgaggttctc tggcaagggc agcccttgca tcaggtacgc
    39001 gacagctacc atcaaaacct gttatggata ggccatcagc cggggatcaa aacccggctg
    39061 acggcgttag aaaatctgca cttttatcat cgcgatggcg atgccgcaca atgtctggaa
    39121 gccctggcgc aggccgggct tgccggattc gaagatattc cggtaaatca actttctgcc
    39181 gggcaacaac gccgcgtcgc tttagcgcgt ctgtggctga cccgtgccac gttatggatc
    39241 ctcgacgagc cttttaccgc gattgacgtt aacggcgtcg atcgtctgac ccagcgtatg
    39301 gcgcagcata cggagcaggg ggggattgtg attctgacta cccaccagcc gctcaacgtt
    39361 gctgaaagta aaattcgccg catttcactg acgcaaacgg gggccgcatg atgttctggc
    39421 gcattttccg tcttgagctg cgcgtagcgt ttcgccatag cgccgaaatc gccaacccgc
    39481 tgtggttctt cctgattgta attacccttt ttccgctcag tatcggtccg gagccgcaac
    39541 tgctggcgcg tattgcaccg ggcattatct gggttgctgc gctgctttca tccttgctgg
    39601 cgctggaacg actgttccgt gacgatttgc aggacggcag tcttgaacaa ttgatgttgt
    39661 tgccgttacc cttgcccgcc gttgtgctgg cgaaggtgat ggcgcactgg atggtaaccg
    39721 gtctgccgtt actcatcctt tcgccactgg tagcaatgct actgggaatg gatgtttatg
    39781 gctggcaagt gatggcgctg acgctgctgc tgggaacgcc tacgcttggc tttctcggtg
    39841 caccgggtgt ggcgttgact gtgggactta agcgcggtgg tgtgctgctc agcatactgg
    39901 tgttaccgct gactatccca ttactcatct ttgccaccgc cgcgatggac gcggcttcca
    39961 tgcatttgcc cgttgacggg tatctggcaa ttttaggcgc gttgctggca ggcaccgcga
    40021 cattaagtcc ttttgcgacg gcggcagcgt tacgaatcag cattcaataa cgctggatta
    40081 ctgatttttg ttcgagtctg gtatcgaaac tatgtggaaa acactgcatc aactggcgat
    40141 cccaccacgg ctgtatcaaa tctgtggctg gtttataccg tggctggcaa ttgccagtgt
    40201 ggtcgtgctt accgtcggct ggatctgggg attcggcttt gctccggctg attatcagca
    40261 gggaaatagc taccgcatta tctacctgca tgtgcctgcg gcgatctggt cgatgggcat
    40321 ttatgcatca atggcggtgg cggcttttat tggccttgtc tggcagatga aaatggccaa
    40381 cctggcggtg gcggcgatgg cccccattgg tgccgtgttt acctttattg ccctggttac
    40441 cggctctgca tggggaaaac cgatgtgggg cacctggtgg gtatgggatg cacgtctgac
    40501 ttctgaactg gtgctgctgt ttttgtatgt gggtgtgatt gccctgtggc acgccttcga
    40561 cgaccgccgt ctggcgggcc gtgcggcagg tatcctggtg ctgattggcg tggtgaatct
    40621 gccgattatt cattactccg tggagtggtg gaacaccctg catcagggat caacgcggat
    40681 gcagcaaagt atcgatccgg cgatgcgttc gccgctgcgc tggtcgattt ttggcttcct
    40741 gctgctgtct gccacgctga cgctgatgcg gatgcgtaat ttgattttgc tgatggaaaa
    40801 acgccgtccg tgggtgagtg aactgatact gaaaagaggc cgtaaatgac ccctgcattt
    40861 gcttcctgga atgaattttt cgcaatgggc ggttacgcct tttttgtctg gctggcggtg
    40921 gtgatgaccg ttattccgct ggtggttttg gtcgtgcact cggtgatgca gcatcgcgca
    40981 attctgcgtg gtgtggcgca acagcgggcg cgtgaggcgc gtttacgtgc tgcgcaacag
    41041 caggaggctg catgaatatt cgccgtaaaa accgcttgtg gattgcctgt gccgtgttgg
    41101 cagggctggc gctgactatc ggtctggtgc tatatgcgct gcgctcgaat atcgatctct
    41161 tttatacgcc gggggaaatt ctctacggca agcgtgaaac tcagcaaatg ccggaagtcg
    41221 ggcagcgtct gcgcgttggc gggatggtga tgccgggtag tgtgcagcgc gatcccaatt
    41281 cgctgaaagt gaccttcact atttacgatg ctgaaggctc agtggatgtc tcttaccaag
    41341 gcattttgcc ggatctgttc cgtgaagggc agggcgttgt ggtgcagggc gagctggaaa
    41401 aaggcaatca tatcctcgcg aaagaagtgc tggcgaaaca cgacgaaaac tacacgccgc
    41461 cagaagttga gaaagcgatg gaagctaacc accgtcgccc ggcgagtgtt tataaggacc
    41521 cagcatcatg atgccggaaa ttggaaacgg gctgctgtgc ctggcgttag ggattgcgct
    41581 gctgctgtcc gtgtatccgc tatggggcgt ggcgcgcgga gatgcgcgca tgatggcgtc
    41641 ttcccgcttg tttgcctggc tgctgtttat gtctgtggct ggcgcatttc tggtgctggt
    41701 caatgctttc gtggtcaacg actttaccgt cacctatgtt gccagcaact ccaataccca
    41761 gcttccggtg tggtatcgcg tggcggctac ctggggcgcg catgaaggct cgctcctgct
    41821 gtgggtgctg ctgatgagcg gctggacctt tgcggtggcg atttttagtc agcgtattcc
    41881 gctggatatt gtggcccgcg tactggcgat aatggggatg gtcagcgtcg gctttttgct
    41941 gttcattctc tttacctcta acccattctc acgcacgctg ccgaacttcc cgattgaagg
    42001 gcgcgatctt aacccgctgt tacaggatcc ggggctgatc ttccatccgc ctctgcttta
    42061 tatggggtac gtgggtttct cggtggcgtt tgcttttgcc attgcttctt tgttgtgcgg
    42121 gcgtctggac agcacttatg cgcgttttac tcgtccgtgg acgctggcgg cgtggatctt
    42181 cttgacgctc ggcattgtgc tcggttccgc atgggcctat tacgaactcg gctggggcgg
    42241 ctggtggttc tgggatccgg tagaaaacgc ctcgtttatg ccgtggctgg tggggactgc
    42301 gctgatgcac tcactggcgg tcactgaaca acgcgccagc ttcaaagcgt ggacattact
    42361 gctggcaatc agtgccttct cgttgtgtct gctggggact ttcctggtgc gttccggcgt
    42421 gctggtatcg gtacacgcgt ttgcctctga tccggcacgc ggtatgttta tcctcgcctt
    42481 tatggtactg gtgattggtg gttcgctgct gctgtttgcc gcgcgtggac acaaagttcg
    42541 ctcacgcgta aacaatgcgc tgtggtcgcg ggaatctctg ctgttagcga acaacgtttt
    42601 gctggtcgcc gcgatgctgg tggtattact ggggacgctg ctgccgctgg tgcacaagca
    42661 actgggactg ggcagtattt cgattggcga accgttcttc aacaccatgt ttacctggct
    42721 gatggtgccg tttgcgctgc tgcttggtgt cggtcctctg gtgcgctggg ggcgcgatcg
    42781 cccacgtaaa atccgcaatt tattgattat cgccttcatc tcaacgctgg tgctgtcgct
    42841 gctgctgccg tggctgttcg aaagcaaagt tgtggcgatg acggtgctcg gcctggcaat
    42901 ggcctgctgg attgctgtgc tggcaattgc ggaagctgcg ctgcgtattt cacgtggcac
    42961 gaaaaccacc ttcagttatt ggggaatggt ggcggctcac ctggggctgg cagtgacaat
    43021 tgttggcatt gcttttagcc agaactatag cgttgagcgt gatgtgcgca tgaagtccgg
    43081 cgatagcgtc gatattcatg aatatcgctt caccttccgt gatgtcaaag aggtgactgg
    43141 cccgaactgg cgtggcggtg tggcgactat cggcgtaacg cgcgatggca agccggaaac
    43201 ggtgctgtat gcggaaaaac gttattacaa cactgccggg tcgatgatga ccgaagcggc
    43261 aattgacggc ggcatcacgc gtgacctgta cgccgcgctc ggtgaagagc tggaaaacgg
    43321 cgcgtgggcc gtgcgtcttt actacaaacc atttgttcgc tggatttggg cgggcgggct
    43381 gatgatggcg ttgggcggac tactgtgtct gtttgatcct cgctatcgta agcgcgtgag
    43441 tccgcaaaaa actgcgccgg aggccgtatg aagcgcaaag tattgttaat tccgttgatt
    43501 atcttcctgg cgattgccgc ggcgctgctg tggcagctgg cgcgtaatgt cgaaggggat
    43561 gatccgacca atctggaatc ggcgctcatt ggcaagcctg tgccgaagtt tcgtctcgaa
    43621 tcactggaca atccggggca gttttatcag gcggatgtgc tgactcaggg caaaccagtg
    43681 ctgcttaacg tctgggcgac ctggtgtccg acctgccgtg cggaacatca atatctgaat
    43741 cagctttcag cgcagggcat tcgcgtggtc ggcatgaact ataaagacga tcgccagaag
    43801 gcaatcagct ggctgaaaga gctgggcaat ccttacgcgc taagcctgtt tgatggcgac
    43861 ggcatgttag ggctggatct cggtgtctat ggcgcgccag aaacgttcct tattgacggc
    43921 aacggcatca ttcgctatcg ccatgcgggc gatctcaatc ctcgcgtctg ggaagaagag
    43981 atcaagccgc tgtgggagaa atacagtaag gaggccgcac aatgaggttt ttattgggcg
    44041 tgctgatgct gatgatctcc ggctcagcgc tggcgaccat cgacgtgttg cagtttaaag
    44101 atgaagcaca ggaacaacag ttccgtcagc tcactgaaga actgcgctgc ccgaaatgcc
    44161 agaataacag cattgccgat tccaactcga tgattgccac cgacctgcgc cagaaagtgt
    44221 atgaactgat gcaggaaggt aaaagtaaga aagagattgt cgattatatg gtggcgcgtt
    44281 acggcaactt cgtcacttac gatccgccgt taacgccgct gaccgtgctg ctgtgggtgc
    44341 tgccagtagt ggctattggc attggcggtt gggtcattta cgcccgctcg cggcgtcggg
    44401 tacgcgtggt gccggaagcg tttcctgaac aaagcgtgcc ggaaggtaag cgtgccggat
    44461 atgtcgctta tttgccgggc attgtggtgg cgttaattgt ggctggcgtc agctactacc
    44521 agaccggaaa ttatcaacag gtgaaaatct ggcagcaggc cacggcacag gctccggcgt
    44581 tgctggacag ggcgctggat ccgaaagccg atccgctcaa cgaagaagag atgtcgcgcc
    44641 ttgcgctggg gatgcgtact caactgcaaa aaaatccggg agatatagac ggctggatta
    44701 tgttgggccg cgttggcatg gcgctgggta acgccagtat cgccaccgat gcatacgcta
    44761 ctgcgtatcg cctcgatccg aaaaacagtg atgccgcact gggttatgct gaagcgttga
    44821 cacgttcatc tgatcccaac gacaaccgcc tcggcggcga actgctgcgc cagttggtga
    44881 gaacggacca tagcaatatc cgtgtgctaa gcatgtatgc gtttaatgcc tttgagcagc
    44941 agcgatttgg cgaagccgtt gccgcgtggg agatgatgtt gaaactctta cctgccaacg
    45001 atactcgccg tgcggtgatt gaacgtagta tcgcgcaggc gatgcaacat ttgtcgctgc
    45061 aggagagtaa ataaaaagag gcccgatggt gatgccatcg ggctattttt attgtgcccc
    45121 gcgttgttgc aggaacagaa tggtggccgc cacgcgtgag cggacattga gtttacgcag
    45181 cagattgcga atatgtactt ttactgtctg ctcggaaata ttcaataccg aggcaatctg
    45241 tttatttgac agcccctgtg ccagctcgtg cagaacatcc agctcgcgct ccgtcagcac
    45301 gctgaaggga tcttcttccg cgccaaacat ttcacgttca cgtaagtact gattgacgcg
    45361 ttcgctaaag actttgctgc ctttcgctcc ggcacgaatc gcttccagca atacttccgg
    45421 gtcgctgtct ttcaacagat aaccgtctgc gcctgcgtct atcagcgcaa agacatcgct
    45481 ggaggcatcg gatacggtca ggataataat ttgcgcggta acgccatccc tgcgcaaggc
    45541 attgagggta tccaggccac tcataccttt catattgaga tccagcaaga tcacgtcgat
    45601 atccagtcta ttcgccagat cgatcgcgct cgcgccgtcg cccgcttcgg cgaccacttc
    45661 aaagccagga tcaagctcca gtaactgacg aacaccgcgt cgcataagtg gatgatcatc
    45721 cacaatcatc acctgaaaag gcgttgcttc aggcatagta gtctcctgag gttttattag
    45781 aatcattatg tttgagcgta gcgttggtaa cgctaccagg cgcgtgaatg ttaccccatt
    45841 ttatgtatgg acatgtagtg aaaactacaa ccttgtcgtt cgctttggca tcattttcat
    45901 tataaagacg gaattttgca tcagcttctc atcaagaaaa acaactaaaa aatcaatcac
    45961 aatacttgtg catttcttta aacagttttt aaaaactgac tccgggtatg gagctatggg
    46021 tattttccgt acccaatgct tttaacagca attaatttca taggatgaaa gctcaattca
    46081 tcaatctggt tctgtttctc tttgtcgttc cgcaatatct gttctggtgg ctacagcgtt
    46141 atattcaccc atagcattgg catcaacagt tgagtatggt gagacagttg atggtgttgt
    46201 cctggaaaaa gatatccagc tggtttatgg gaccgccaat aatacgaaaa tcaatcctgg
    46261 cggagaacag catataaaag aatttggtgt aagtagtaat actgaaatta aaggagggta
    46321 tcagtacatt gaaatgaatg gtaccgcaga atactcagta ttaaatgacg gttatcaaat
    46381 tgttcaaatg ggtggcgcgg caaaccagac taccctcaat aatggtgtgc tacaggttta
    46441 tggcgcagcg aatgatccca cgattaaagg cgggcgctta atcgttgaaa aagatgggat
    46501 taccgtcctt gccgctatcg aaaagggagg attactggag gttaaagagg ggggattagc
    46561 gattgcggta gatcagaaag caggcggtgc tattaaagca agcacgcggg tcatggaggc
    46621 attcggaaca aaccgtctcg gtcagttcga aatcaagaat ggtattgcta acaatatgct
    46681 gttggaaaac ggcggaagtt tgcgagttga agaaaatgac ttcgcttata atactactgt
    46741 agatagtggc ggcttactgg aggttatgga tggcgggact gtaactggcg ttgataaaaa
    46801 agcaggcgga aaattaattg tctcaacgaa tgcgctggaa gtgagtggta caaacagtaa
    46861 aggccaattt agtataaaag atggtgtgtc aaaaaattat gaactggatg atggttccgg
    46921 gctcattgtt atggaggaca cgcaggccat tgatactatc cttgatgagc atgccactat
    46981 gcaatcgctg ggaaaggata ctggtacgaa agtgcaggca aatgcggtat atgatctcgg
    47041 tcgatcagat cagaatggaa gtatcacgta ttcctcaaaa gccatttctg aaaatatggt
    47101 tatcaacaat ggccgcgcta acgtctgggc tggcacaatg gttaacgttt cagtcagagg
    47161 gaatgatggc attcttgagg tcatgaagcc gcaaataaat tatgcacccg caatgttggt
    47221 gggtaaggta gtggtttctg agggcgcttc ttttagaacg catggtgccg tggataccag
    47281 caaagcggac gtttcgctcg aaaatagcgt atggaccatc attgccgata tcactacgac
    47341 gaaccaaaac accctcctca acttagccaa ccttgcgatg tctgacgcaa atgtgattat
    47401 gatggatgag ccagtgactc gttcatcagt gacggcaagt gcggaaaatt tcattacgtt
    47461 gaccaccaat accctgtcgg gaaacggcaa tttttatatg cgtaccgata tggctaatca
    47521 tcagagcgat cagctcaacg tcaccggtca ggcaacaggt gatttcaaaa tattcgtgac
    47581 ggacaccggt gccagcccgg cagcaggaga tagccttaca ctggtaacaa cgggcggcgg
    47641 tgatgctgca tttacgttgg gcaatgccgg aggcgttgtt gatatcggta cgtatgaata
    47701 taccttgctg gataatggca accatagctg gagtttggca gagaatcgcg cgcaaattac
    47761 cccttcaacc actgatgtgc tgaatatggc ggcagcacaa ccgctggtat ttgatgcaga
    47821 actggacacc gtgcgtgagc gtcttggtag cgtaaaaggc gttaattacg atacggcgat
    47881 gtggagttcg gcaattaaca cccgcaacaa cgtgaccact gatgcgggcg ctggctttga
    47941 gcaaacattg accgggctga cgctcggtat cgatagccgt ttctcccgtg aagaaaccag
    48001 cacaattcgc ggcttgttct ttggttactc tcattctgat attggttttg atcgcggcgg
    48061 caaaggcaat gtcgatagct ataccctggg ggcttatgcc ggttgggagc atcagaacgg
    48121 tgcctatgtt gatggagtgg tgaaagttga ccgttttgcc aacaccatcc attgcaagat
    48181 gagtaatggg gcaacagcgt ttggcgatta caatagtaac ggcgcgggtg ctcatgtcga
    48241 gagcgggttc cgttgggttg acggattgtg gagtgttaga ccctatctgg cctttaccgg
    48301 ctttaccaca gatggtcagg actacacgtt atcaaacggc atgcgcgcgg atgtgggaaa
    48361 tacccggata ttacgcgctg aagcgggaac ggcggtaagc tatcacatgg acctgcaaaa
    48421 cggtacgacg ctggaaccct gactgaaagc cgccgtgcgt caggaatacg ccgattctaa
    48481 ccaggtgaaa gttaatgacg atggcaaatt taataatgat gtggctggaa cccgtggcgt
    48541 ttatcaggct gggataaggt catcgtttac cccgacgtta agcggtcatt tgtcagtcag
    48601 ctatggcaat ggcgcagggg tagaatcgcc gtggaatact caggcgggtg tggtctggac
    48661 gttctgataa caaaaaataa acaggctgtg atgtgtcacg gtctgtttat cgaattaatt
    48721 gcagatataa aaaaaaccaa ccgtaaaggt tgattttttc ttgggatttt tggtcggcac
    48781 gagaggattt gaacctccga cccccgacac cccatgacgg tgcgctacca ggctgcgcta
    48841 cgtgccgact cgtggctgct aatactaccg ttttccacac cgattgcaag taagatattt
    48901 tgctaactga tttataatta atcagttagc gataaaacgc ttctcgtctg tcagcacttg
    48961 caataacaaa cttaactgtg gtttttcatc tttcactctt tcaccacgta agttgtaagt
    49021 gcggtattta ccgttattgt tcagcaccag cgtctttttc ggggtggtaa ttgccagcgt
    49081 atcgttatcc gctgcagtaa cccagtaatg acggcgttga gggttgaaca aatcctgacc
    49141 ttgcgaatat tcgctggcag gtgtgctgac atgtagcagg cgttgcatca gcgtcgtcat
    49201 cagatcggta tgatcagtca gagcattaat acgctgcgcc ggcgtgcctg gccagtgaat
    49261 cactaatggc acctgcagat gaccgtggga ccagtcaaag gtttcttcgt cttcgctcag
    49321 cggaataccc cgaccggcag tgataatcac caccgtattg tccagtttgc cagaatcacg
    49381 cagtgcattg agcacgcggt tgatctggtc atcgacattg cctgccgccc ggctatattt
    49441 ccgtgcaaat gcctgctgat tgctgtcgtc aatgttagtg ccattgaaag agacccacga
    49501 gaaccagcgg ttatcttctt gtgcgtagcg gcccagccag ttgatccact gcgtggcggt
    49561 ctgctcgtcg gattgggtgc gtacgctcgg catcgagaaa tctgacaaca atgcctggcg
    49621 atacagcggg ctggtaaagc catctgatga gaataatccc agctgatagc cttgctgatt
    49681 aagcgcagta attaacgccg caggggtacg ggtcgacaga atgccgtcca tatagctcgg
    49741 cgagatgcca tagaacaggc caaagatgcc gttgtctgta gtgttgccgg agctcatatg
    49801 gcgcgtgaac gaaatatttt gctcagcaaa acctgccagc gcaggcatct gcttctcgaa
    49861 gcgtgagtag ttcaggccat cgacagtaat caacagcaca ttctgcccgg tgcccatatc
    49921 gcgatagcgc agttcgctta acggatactg aacggaaacg gcgtctggat taccttgctc
    49981 aataagacgg cgttgatact cctgcgcatc aagcagacca tgcttctcaa gaaaacgtcg
    50041 cgccgtcatc gggtacgaaa gcggcaggtt agcgcgctgc atggtgatcg ggcgatagaa
    50101 gttggcatcg gcccagatat acaccacatg cgaggcgata aaggcgataa ataagaatgc
    50161 ggccagcggg cgcgcgaagc gccgacgacg cgtcaggctg cgcagctttt gccagctcca
    50221 cgtcgcaaac accagttcaa gcaataaaat aaccggcacg ctgatgaaca tcagctgcca
    50281 gtcgcgcgcc atctcatttt cgtctgggtt gataaccagt tgccagacga tgggattaag
    50341 atggagatgg aaacgagtaa agacttcgct atcgatcagt aatagcgtca ttcccgccgt
    50401 tgccagaatg acggacaaaa acctcatcag cctctgggag ccgacgataa aggtcagcgg
    50461 gaagaggatc agcaagtagg tggcgaacac caggaagctg aaatggccga taatgcttac
    50521 gtaggaataa atgcgaccag caagcgttgt cggccagtcg gcgataaaca ggtaacggct
    50581 gccaatgacg agcgaaagca gaatattgaa cagtgcaaac cagtgccccc aactgaccat
    50641 ctgggagact ttttcacggt agcgctgacg atgagttacc ataacctgtt atctgtttcc
    50701 cttagtgcgc tttgtcttcg ttgatagagg actgtaaggc gcgggcaaaa gagttggcaa
    50761 ttgcctggcg ttgggccggg gcaatgctgg tattgataag gttagtgacc atgttgccta
    50821 acaccatcag ggaaaggtcg gtcggagcct tatgtttttc cagtacgttg agcagctctg
    50881 cgagcaattg ttcaacctgt tcatcactgt agcgggaaat ttgtggcata aatcgaaatc
    50941 agttagttga tgaaagggca acatattacc gtagcaacgg ttttttttct gcttttttat
    51001 gcgttaaatc attctcgtta cgctgccttc tgtaaaatga ccgccatctt ttattgcgtc
    51061 gcttaaccgg cggtggttga ataccgcccg gtcttaaagg agagtttatc atgagtctgg
    51121 atatcaacca gattgctctg caccagctta tcaagcgtga tgagcagaac cttgagctgg
    51181 tgttgcgcga ttcattgctg gaaccgacag aaaccgtcgt tgagatggtg gcagaactgc
    51241 atcgggtcta tagcgccaaa aataaagctt acggcttgtt tagcgaagag agtgaactgg
    51301 cgcagacgct gcgcttacag cgtcagggcg aagaggactt tctggcattt agccgcgcgg
    51361 caaccgggcg cctgcgtgac gaattagcga aatatccttt tgctgacggt ggattcgtgc
    51421 tgttttgcca ctaccgttat ctggcggtgg agtatctgct ggtggcagtt ctgagcaacc
    51481 tgagcagtat gcgcgttaac gaaaatctcg acatcaatcc aacccattat cttgatatca
    51541 atcatgcgga tattgttgcg cgtatcgatt taaccgaatg ggaaaccaat ccagagtcca
    51601 cccgctatct cactttcctg aaagggcgag tagggcgcaa agtggcggat ttctttatgg
    51661 atttcctcgg ggccagcgaa gggttaaacg cgaaagcgca aaaccgtggg ctgttgcaag
    51721 cggttgatga tttcactgcc gaagcacaac tggataaagc agagcgacag aacgtgcgcc
    51781 agcaggttta tagctactgt aatgagcagc tgcaggcagg cgaagagatc gaactggagt
    51841 cgctgtcgaa agagctggca ggcgtcagcg aagtgagttt cacggagttt gcggctgaaa
    51901 aaggctacga actggaagag agcttcccgg cagaccgtag cacactgcgt cagttgacga
    51961 agtttgccgg tagcggcggt ggcttgacta ttaactttga tgcgatgctg ttaggtgaac
    52021 gcatcttctg ggatccggca accgataccc tgaccattaa aggcacgccg ccgaatttgc
    52081 gtgaccaatt gcagcgccgg acgtctggcg gcaattaatc ggttttgtgt tctgaatgcc
    52141 agatgcggcg tgaacgcctt atctggcctg caaaaaatag caataccgta atcaggcata
    52201 atctgcagat acaaaaaacc ccgccggagc ggggtttttt acaacttatt cagcaattaa
    52261 gcgcgaacga agtcgatgtg ctgcagcttc ggtttgtacg ggtgacgctg tacgtcctga
    52321 gctttaactt tgatttcttt accgtcaaca acgatggtca gaacttcgct gtagaattca
    52381 gctttagctt gcatgttcat gactttgtcg tgatccagct cgatagccag cggcgcttct
    52441 ttgccaccgt agatgattgc cgggaacttg ttagcggcac gcaggcggcg gctcgcaccc
    52501 ttaccctgct ctttacgtac ttctgcgttg atagtaaaca tttctttctc tcttaaatta
    52561 atcctgctac aggcgaccca gcaacaggta agtgatctgc tttgcgtatg caaaagcggg
    52621 cgagattcta tactcaatcg ctttatacat caatcaaaac taccattaac cgcgtaattc
    52681 gtgcgcccga cgaaaacgac cttcgtaatc gaacactttt tcacgcactt gccagtactg
    52741 acctttcatg cgggcaacga caaaatccgg gtgtcgcaat aaggcttgct gggcgaggat
    52801 atcggcggcg gtgatccagc gcagagggat gcccggtgtg cgcgtatgcg ggcggataaa
    52861 aagctgctcg aaggcagttc gctgggcggg cgtttgcaga cggaaacgct cactcacatc
    52921 cgcgccgtct tcatcgtaat aggtgatttt caaccattcg cctttctcgt cgtgctcatg
    52981 ctgcaaagac atgccgctac agcgtaatac cagcgcatct ttcagtcgta gcgccgcttt
    53041 taacatatca tccggatcaa ccagtaccgt gtcacattcg cggcagcggc gagcggcaat
    53101 atcattttct gcgttacatt gcgggcaatt tttaaaacgg aaacggaagt cacactgttc
    53161 gcgatgaccg tcgtcatctt caaaccatcc ctgacagcgg cgaccaaagt gttcaatcaa
    53221 tgtcccgtcg gcggtcgttt tcccccaaaa ggtgttggca aaaccgcagg cagggcagaa
    53281 aacctgtacc ggaacgttgt cacttttgcc tttcggtgta ccaacttccg gcgcgtagag
    53341 atcgtgagga ttacccgcat aatcaagaat taaacaatca gtcttgcccg gagcgagacg
    53401 cagaccgcgc ccgacaattt gttggtaaag actcactgat tcggtagggc gcagaatggc
    53461 gataagatcg acgtgcgggg cgtcaaatcc ggtggtcagt actgcgacgt tgaccagata
    53521 gcgaaaacgc tgggctttaa aatcttcaat taacacatcg cgctcagcgc cgggggtgtc
    53581 gccagtaatc agtgcagcat cttcggcggg tagtaatccc acaatctctt ttgcgtgttc
    53641 aacggtggcg gcgaaaatca tcaccccttt gcgcgttgca gcaaactcca taatctggct
    53701 gatgatgtgc ggggtaatac gttgttgttt ttttagctcg cggttgagat cagcttcgct
    53761 gaacagcccg ttactctgtg cctgcaagcg gctgaaatcg tattgcacta ctggcatatc
    53821 cagtcgttct ggcggcgtca gatagctgtg tttaatcata taacgcagcg gcagttcata
    53881 aatgcagtca cggaaaaggg ctttctcatc gccgcgtacc atgccgtgat aatggaactg
    53941 gtagatccag cctttgccca gtcgaaaagg cgtggcagtc agccccagca ggcgtaagtg
    54001 gggattcact tttgtcaggt gagtgaggat ttgctgatac tggctctctt catcgtcacc
    54061 aatacggtga cattcatcga caatcaacag cgaaaattca ccctgaaagg catcaagatt
    54121 acgggcgacc gactgcacac tgccaaatac cactttaccg tggctctctt tacgctttag
    54181 cccggcggca aaaatatcgg cttccagccc cagcgcctga tactttgcat ggttttgcgc
    54241 caccagttct ttaacgtgtg ccagcaccag tacgcgacca cgagccagcc gtgccagttc
    54301 cgctatcacc aggcttttac ctgcgccggt gggcagcacg ataacggcag gggttttatg
    54361 acgacgaaaa tggttgagcg tggcatccac ggcttcttgc tgatatgggc gaagtgtaaa
    54421 aatcatggtc tcgcgtaggt agattattct gctaatagta tgccacggtt ctttttccct
    54481 tgagggaagt tattagaccg ctatactggg cagacaacag ttcagatttt cgggtcaatg
    54541 cccgacctcc gtttttacag gcaaaatcac acacatgcga cttgataaat ttatcgcaca
    54601 gcaactcggc gttagccgtg ctattgccgg gcgtgaaatc cgcggcaatc gtgtcaccgt
    54661 cgatggcgaa atcgtccgta atgcagcgtt caaactgctt cctgaacatg atgtcgctta
    54721 cgatggcaac ccgctggcgc agcaacatgg tccacgttac ttcatgctca ataagcctca
    54781 gggctatgtt tgctccacgg acgaccctga tcacccaacg gtgctctatt ttctggatga
    54841 accggtagcc tggaaactgc acgccgcagg acgtctggat atcgatacca ccggtctggt
    54901 gctgatgact gatgatggtc agtggtcgca ccgcattact tctccgcgcc atcattgcga
    54961 gaagacctat ctggtgacac tggaatcacc tgtagctgac gatacggcag agcaatttgc
    55021 caaaggcgta cagctgcata acgaaaaaga tctcactaag cctgcggtgc tggaagtgat
    55081 taccccaacg caggttcgtc tgaccatcag cgaagggcgt tatcatcagg tgaaacgcat
    55141 gttcgccgct gtgggtaacc atgtggttga gctgcatcgt gaacgtattg gcggtattac
    55201 gctggatgct gatttagccc ccggtgaata tcgtccgtta actgaagaag aaattgccag
    55261 cgtcgtctaa cttttccatg actttcagga gcccgttgtg accacccgac agcattcgtc
    55321 gtttgctatt gtttttatcc ttggcctgct ggccatgttg atgccgctgt cgattgatat
    55381 gtatctgccc gcgctaccgg taatttcagc gcagtttggc gtacctgcgg gcagtacgca
    55441 gatgaccctc agtacttata ttctgggctt tgcgttgggg cagttaatct acgggccgat
    55501 ggcagacagc ttcgggcgta agccggtggt gctcggcggt acgctggtgt ttgccgccgc
    55561 cacggtggcg tgtgcgttgg caaacaccat cgatcagctg attgtgatgc gtttcttcca
    55621 cgggctggct gcggctgcgg ccagcgtggt cattaacgcc ctgatgcgcg atatttaccc
    55681 gaaagaagag ttctcgcgga tgatgtcgtt tgtcatgctg gtgaccacta ttgcaccgct
    55741 gatggcaccg attgtcggcg gttgggtgct ggtgtggctg agctggcatt acatcttctg
    55801 gatcctggca ttagcggcga ttctggcttc ggcaatgatt ttcttcctga ttaaagaaac
    55861 cttaccaccg gagcgtcgcc agccttttca cattcgtacc actattggta actttgcggc
    55921 gctgttccgt cataagcgtg tcctgagtta tatgcttgcc agtggtttca gctttgccgg
    55981 gatgttctcg ttcttaagcg ccggaccgtt tgtctacatt gaaattaacc acgtcgcgcc
    56041 ggaaaacttt ggttattact ttgcactaaa cattgttttc ctgttcgtga tgaccatttt
    56101 taacagccgc ttcgtccgcc gcattggcgc gttaaatatg ttccgctcgg ggttgtggat
    56161 acagtttatt atggcggcgt ggatggtcat cagtgcgctg ctggggctgg gattctggtc
    56221 gctggtggtt ggcgttgcgg cgtttgtggg ctgcgtgtcg atggtgtcat ccaatgcgat
    56281 ggcggtcatt cttgatgagt ttccccatat ggcgggaacg gcatcttcgc tggcaggaac
    56341 cttccgtttt ggcatagggg caattgttgg cgcattgctt tctcttgcga cctttaactc
    56401 tgcatggccg atgatttggt caattgcatt ctgcgcaacc agctccattc tcttctgtct
    56461 gtacgccagt cggccgaaaa aacggtgatc tattgcacaa cgaggaagct aaaaggcttc
    56521 ctttgttgat gcatgtcaac cacaaatcta tcattccccc gatatatgtt tattttatgt
    56581 aaaatcaatt tatgtaaaaa gtcacatcat tgtagttaaa aaggttgagt tagatcgcag
    56641 aaacgggtac atatagcccc gcaaacgtga ccacgcccgc agatattact taaatcagag
    56701 ccatagaggc cactcaggcg aggcatcaat ctttacgatc tgtataaaga cggattgttg
    56761 atgatgtgtt aaaattgatg taaacaaatt gtgaagtaaa tgtacttccg gggaaaataa
    56821 gtgacttcat tacaactctc aatcgtccat cgtctaccgc agaactatcg ctggtctgct
    56881 ggtttcgcag gttcgaaggt tgaaccgatt ccgcaaaatg gaccgtgcgg tgacaacagc
    56941 ctggtggcgc ttaaattgct tagcccggat ggtgataatg catggtcggt gatgtataaa
    57001 ctaagccagg cgttaagcga catcgaagtt ccatgttcgg tgctggagtg tgaaggtgag
    57061 ccgtgcctgt ttgtaaatcg ccaggacgag tttgctgcaa catgccgatt gaaaaatttt
    57121 ggtgtggcaa ttgccgaacc cttttcaaac tacaatcctt tttaagcgtc agctcaacgc
    57181 cagtagctga cgcgtatact cctgctgcgg tgtggcaaac acgcgcgcgc acggtccttg
    57241 ttccactact tccccttgtc gcagtacgat aacctgatga cataacgcgc ggacaacgtg
    57301 caaatcgtgg ctgataaaca aataggccag ttgatgcttt tgttgcaatg atttcaatag
    57361 cgtcaatatt tgcgcctgta ccgttttgtc gagtgatgat gtcggttcat caagtatgat
    57421 cagcgagggc ttaagaatta atgccctggc aatcgcaata cgttgtcgct gaccaccaga
    57481 gaactccgcc ggataacggt ggcgtgtttc aggatctaat cccacttcat gcatcacggc
    57541 tatcacttgt tgttcgcgtt gtgcggcaga aagcgtcggc tggtgaaccc gtaagccttc
    57601 ctcaataatc tgcaaaacgt tgagtcgtgg gttgagcgag gagtttggat cctgaaatac
    57661 cacctgaatg cgatgacgaa taggtaacag ctggcggcga tttaaatttt gcagtggctg
    57721 accgtcaaag atgatgctgc cctgagaatt aatcagtcgc agcagcgcca gtcccgtcgt
    57781 acttttcccg gaaccggact cgcccactaa acccagtgtt tcacccgctc gtagcgtaaa
    57841 actgatgttt ttcaccacca cattatgatc cacaatgcgc ttcaaaatcc ctttgcgaat
    57901 ggggaaggca acctgaagct gttcaacatc cagcaacgtt gaggcaggtt ctggcaacgg
    57961 cactggatcg cctgacggtt cactgttgag tagcttttgt gtgtaaggat gagtgggtga
    58021 tgcaaatagc gtagcggcgt aattttgctc gacacagcga ccgttttgca ttaccgccac
    58081 gcggtgggcc agttttctga caatgctgag gttatgagta ataaacagca tgcccatatt
    58141 cagctcgcct tgcagttcgc gcaacagctg taaaatctgc gcctggacag agacgtccag
    58201 tgcggtggtc ggttcatcgg caattaataa ttccggtcgc gttaacagcg ccatcgcaat
    58261 catcacccgc tggcgttcgc cgccggagag ctgatgcgga taatctgtca gccgttttgc
    58321 cgcctggcgg ataccaacgc gatcaaggca gttaagaatt tcgccacgag ccgcttcccg
    58381 acgcatcccg cggtggagtg aaagcacttc ataaagctgt ttttccaggg tatgcaatgg
    58441 atttaacgac accatcggtt cctgaaaaat catggcgatc ttattaccgc gtacaccgcg
    58501 caacgtttga tcgctgacat gaagcagcga ttcgccatga aaacgaatat cgccggagag
    58561 atattcaacc ggcggggaag ggagcaggcg taaaattgac agcgcggtaa cgcttttgcc
    58621 tgaacctgac tcacccacca gcgccagcgt ttcgccagcc tcaatctgta gtgaaacatc
    58681 attgactact gtacgtacgg tttgctgatg gcgaaaaccc accgacaaat tttcaatcgc
    58741 taacagagtt tgcgtcatgc tacaccgcct tattaggatc aaatgcgtcg cggacggctt
    58801 caccaataaa gatcagcaaa gacaataata tcgccaccga caagaaggcg gtgatcccaa
    58861 gccacggggc ctgaaggtta tttttccctt gtaacagcag ttcaccgagt gacggtgaac
    58921 cgagcggtag accgaagccg aggaaatcga gcgaggtcag ggtggttatc gaactacata
    58981 aaataaacgg taaaaaggtg agggtcgcga ccatggcatt aggcaacata tgacgcagga
    59041 tgatactgcg atcgctgacg ccaagcgcct gtgccgcacg aatgtagtcg aaattacgag
    59101 tacgtaaaaa ctccgcccgc accacgccga ccagactcat ccagccaaac aagacagtaa
    59161 ttgccagcag ccaccagaag ttaggctgta cgacgctgga aagtaaaata atcaaaaaca
    59221 gcgtcggcat ccccgaccat acttcaataa agcgttgtcc ccagagatcg actttaccgc
    59281 cgtaatagcc ttgtagcgcc cccgccagca cgcccatcac gctggaacag agagtcagca
    59341 tcaggccaaa cagaaccgag atccgcgtgc catagagaat gcgtgccagc acatcgccgc
    59401 cgttggcatc cgttcccagc cagttttgcc gggagggtgg agaagggaag ggcttatcgg
    59461 tagcaaagtt gatactggta gcaccaaagc gaatcggtgc ccacagtacc cagccgttat
    59521 tttccagccg ttgtttcagc cacgggtcct gataatcagc ctgacttgcc agcgggccgc
    59581 caaaatcgct ttcgctgtag tttttcaaca acgggaaata ccaactgccg tcataacgca
    59641 ccagcaacgg tttatcgtta gcgataagtt cagaacacaa actcaaacca aacaagacga
    59701 ggaaaatcca taacgaccag tatccgcgac ggttatggcg aaaacgcgcc caacgggcct
    59761 gattgacggg gctgagtcgc gacattaacg tccctcaaaa tctatacgcg gatcgaccag
    59821 cgtatagctg atatcactga caatattcag cagcaggcca atcagggtga aaatatacaa
    59881 ggtaccaaac attacaggat aatcgcgcga gacggtcgct tcgtagccca gtaagccaag
    59941 accattgagt gaaaacatca cctcaatcag cagcgagccg gtaaaaaaca tgctgataaa
    60001 cgtcgccgga aaaccggcaa tcaccagcag catggcgttg cggaacacat gtttccagag
    60061 aatgtttttc tcacttaccc ctttcgcacg cgcggtcacc acgtattgct tgcgcacttc
    60121 atcaaggaat gagtttttgg tcagcatggt cagcgccgca aagccaccaa tcactgtcgc
    60181 cagcaccggt agcgtgatat gccacagata atcggtgatt tgctgatacc acggcagcga
    60241 atcaaagtta gcggaaacca ggccgcgtag agggaacagg tcaaaatagc tgccgcccgc
    60301 gaagaagaca atcagcagga tggcaaacaa aaaggccgga atggcgtagc cgatgatgat
    60361 aaatgcgcta ctccagacgt caaagcggct cccattataa acagctttgc gaatgcctaa
    60421 cggaatcgac accagataga taatcagcgt gctccacaat ccgagggtga tggaaaccgg
    60481 cagactgtct ttaatcagcg tcagcaccga ggcgctgcga aaaaggctat caccaaaatc
    60541 aaagcggatg tagtcccaga gcattttgaa gtaacgttcg tggatcggct tatcgaaacc
    60601 gtagcgatga gtgatctcgg cgatcacttc tggatctaat ccgcgtccgc cacggtaatt
    60661 actgtcgctg atattgccga cgcccgtttg cgcatggctg gcgcgaatac cttcaccgcc
    60721 tgcgccgggt aatactccgg cattaccaaa ctcaatggcg gcgatggcct ggtcgaccgg
    60781 accgccaggc gcaatttgca cgatgaaaaa gttgatagtg ataatcgccc ataacgttgg
    60841 gatcaccagc aacagacggc gaatcagata agcgcccatc tactctccct gttgtctggc
    60901 tgacggcagt ttggccgctt tattaacgtc ataccaccag gtatcgatac ccaggctgta
    60961 aacagggcgt acagcgggtt gggagaattt atcccaccag gcgagacggt cttccgccat
    61021 gtaccacatt ggcagcatgt aataattcca cgttaatacg cgatccagtg ctcgccctaa
    61081 cggcagtaat ttttctttat ttccctgcgc ggcaataatt tgattgatca gcgagtcgat
    61141 aaccggactt tgcacgccgg gggcattata agtggaattg atatattccg atgaccagga
    61201 aatctgtaaa tcggaactgg gccacggcat cgcccgccat acgcgcggca tcatgtcata
    61261 gtcgcgactg cgcatgcggt tggtgatttg cgagttatcc accttgcgaa tgtccatgtt
    61321 gatacccagc cgttgcaggc tgtgctggaa cggcaatacc cactgactat tgctgcttgc
    61381 gggaagcaat aattcaaagc tgagtggctg acccgttgtg gcattaacgc gttgctgacc
    61441 cttcagcacc cagcccgctt cgttgagaag tttgtcggct tttaacaggt tgtcacgatc
    61501 gtagccatcg cctttagata ccggcggctg gtagatttgt gtgaagactt ctgacggtag
    61561 atcttttttc attggtgcca gaagcaccag ctccgcggct tcggggtaat ttctggccgc
    61621 gtattcggta ttctgaaaat aactgttcgt gcgactccag gcattgtaaa acaacgcctt
    61681 gttcatccat tcaaagtcaa aggcgagggt gattgcttcc cggacccggc gatcgctgaa
    61741 taccggacgt tggatattaa acgccagcca gcgcgtatcc tgggctgatt cgttcttttg
    61801 ctcatctttg atgatgtatt ttttatcgaa atttttaccg gtataacgcg tggcccagtt
    61861 tttagcgtcg ttttccatac gcaaatcaaa ggcacctgct ttaaacgctt caaaggcgac
    61921 attatcatcg aggtaataat cgtagcgaat ggtgtcgaaa ttccagcgtc cacggtttac
    61981 cggtaagttt gctgcccagt aatctttcac gcgggaatag acaatatttt gccccatttt
    62041 ccaggacgta attcggtacg gaccactggc aagcggaggc gtggcgagcg gatcgctaag
    62101 tttgtgatcc ttccagtact tttctggaaa taccggcagc gaaaacagac tcaacatatc
    62161 ttctttgccg ggtttagcta actcaatgcg cacggttaac ggcgcaatgg ctttgacggt
    62221 ggtgcctttg tagaccagac gaaattgcgg cacgccttcg gtcataaatt tttgaaaagt
    62281 aaactctaca tcgcgggcag taatgggcga accatcatga aaacgggcgc gcggattaat
    62341 agcgacctcc acccaggaat aatcgtcagc atagcgtgcg ctttcagcaa tcagcgggta
    62401 ataactgcct ggttcgtcat cggaagtcgt aaatagcgtg tcgtacagct gctcggtgcg
    62461 tgcgcccggg ttgccgcgca gtgcatagcg gttgaaatta tcgaaggtac cgagggctga
    62521 caacgttatc tgcccacctt ttggcgcggc ggggttcaca taatcaaaat ggttgaaatt
    62581 aaacgcgtac cggggttcgc ccagcacggc aaaggcatag ctttccttga tagcctgcgc
    62641 ctgcgcacca aaggtgaaca gagcgataaa cagcagcagt atgcgcacaa tcatctgcaa
    62701 cggatttcct tttactcatc attagccgca atccggcatg ctttcactat gaataataag
    62761 ggacgtaagc acaccttacc actgcggcgt atacggtttc tttagccagc gaacaaaatc
    62821 gtccagcggt aacgggcgac taatccagta gccttgcatg aaattaacgc cgcgttcgct
    62881 tagccatcgc gcctgttccg gcgtttcgac cccttcagca accgtcagca tattgaggcg
    62941 tttcgccagc gtcagcaccg cgtcaagtac gggtgaagtg atcgtttccg taccgatggc
    63001 gttgataaat ccacggtcaa ttttcagata atcgagcgta aaacgctcaa gatagataag
    63061 cgcgctgtgc ccggtgccga agtcatcaat agcaatttct acgccgaccg agtgcagcca
    63121 ggcgaagagt tgtgtggctt cttgctcttt cagcatatcg cgctcggtaa tttccagcac
    63181 aatctggaaa tggtgtgcgg gtagggaagt gagcagtttc tggatatctg ctttaaagct
    63241 ttcgctgtgc agatggtccg gcgcaatgtt aatgccaaat ttgacgccta ccggcagcac
    63301 tttttctaat tctgcggcat cgcgggcaat taactcaaac aggtgctgag tcagcggcac
    63361 aatcatcttt tgcgattcgg caaagttaat gaaggcatcc gggggaattt ctcccgcgac
    63421 aggatgccgc cagcgtagca gtacttccag gcccgttact cgcaaagctt gtgtatccac
    63481 caccggttga tacgccacgt aaaattgttc gcgcttgatg gcggtcatga tttctctgcc
    63541 ggggcgcata cgtacgctca tcaggtaata gcagagcagg ccaacgacag ttccactcat
    63601 gccgcccagt aaaaatgcgt accacacatc gttccatgtc cagtcatccg cataaagccg
    63661 aacggtcaga ggaatgcccg caattttagt ttcacggacc ggcatgtcgg ttaattcatt
    63721 aacgttcatc aaacgtgaag aaaaggtaga tagcgcagta ttgccaataa tgagggcgac
    63781 gccatcgtaa tcttcctgcc gtgaactata aaagagagaa ggcgtcaggt tgagattcag
    63841 agcggcaaac acaccgctat ttttcagcaa agggttgcga taccagatga cgattgcggg
    63901 tttgttcggc accatcggcg tgccgggtaa gatcgccata tcgacgtttt tattaatgtc
    63961 gagcgccgga atcaattcat tgagtggaat gtccatctca ccagtcgcag atgaacagaa
    64021 tgttttttta tctttcacca gcacaaacgt acggacattc atgctaaacg ccgcgcgagc
    64081 ggtcagttcg gggttagcct gctggcaggt atctaaggtc agcggctgaa gccggtcagt
    64141 agtggatttc aggtcggcaa aataggtatc gagatacttt tgtacgtcga taatcagtgt
    64201 gtcgtatttg acttcgtgct tatgccaggc cactaaaaat tgaaggcaac tcaccagtat
    64261 cgcaatcatc acgcctgcaa caatgcaggt aagcaggagc ttacgtccag aattgggagc
    64321 gcgtatgaac atgattccgt taatttcctg aaattacgac aacatttaaa agataacaat
    64381 gaccggacta tagcctggat caagacgcgg aaacatcatt ttctctgatg aatgaaaaca
    64441 aaaaagcact gcctaagcag tgctttcagt taactcgtca ggatagccaa gggattgcat
    64501 ccaaacggtt tattagctgc ggctgagaac ccggcgtgct tcgttgtaac gcttcttcca
    64561 gtacggttca ttcatgctgg aaataataac accactgctg gtggaagcat ggacaaactg
    64621 attgttgccg atataaatac cgacatggcg tcccgttgaa ccggcacgga acagaactaa
    64681 atcacccgta cgcaaattac tgcgggaaac agatttaccc atttcctgct gttcgtaagt
    64741 cgaacgcgga agttctaagc caaattgctc acggaatgta cgctgtacga aaccagaaca
    64801 atcgatacct tttttagtgc tgccgcccag acgataacgt acgcctttcc agtcagcata
    64861 ctgatccata attcgcgatt ttacgtcgac attacgaacc aggttttcaa attcatcctg
    64921 agaagcttgc agtgatgatg tttcactacc cactgcacgt gtctcaggat gcatattctt
    64981 tgcggtgtta tttgcactac atgcagaaag cagaaccgct actgcaatcg cgggaatccc
    65041 gcgcaagata tatctcaaaa tcggttgaga tttgaccatg ttgtttgttt tcccttgaag
    65101 tccttaacga caaatatcgt tataaaaaaa tgccaagcga cacgagacta attacctggg
    65161 catgttgaaa caattcctta aggccaaatc tgtggactaa cgcacaaaat tatatgctgt
    65221 gaggataatc taccgccgag gcaaaacgag ttcgagatta cccgattggt gcggtcttgg
    65281 cgagcggttt tacatgattt tttataagaa aaagtgatac agaaagttaa taagcgggat
    65341 tggtcaatta aagtacgatt gagtgaaacg catgcaatcc attcatttac ttagagaatg
    65401 atttttgcgc gcgatggatg aaagcacggt gcgcatcatc aggattatcc tcactataaa
    65461 aataagcctg atgatgttaa ttactgtgag ttatttgttt tggaaatgtt tgttttttcc
    65521 cggtagtgat ttgtcaaaaa aggtgattaa tcgatcactt aatggcgtca gcaacaccca
    65581 gggcaaaccg atcaatatca cggtcatcga accgacaatg atgtcagtaa accagtgtgc
    65641 gccaatcatt actctgggaa atgcaaaaac cacaaaaata ataagggcga taaggcctgc
    65701 aactttgccg aaataacgcc acatgaatgc cgaaaaaata agcagcatca tgccgtgatc
    65761 gccgggaaag ctatctcgtg aggcatcttt cgtgggaaca gagagcagtt cgctgacgcg
    65821 gttaatatcg gtaaaagtca atgttgggct ggcccgtttt acaggaatta atgcctgacc
    65881 cagctggttt aataccactg cagttaatag catgaccaga cccataatca cgatacgtcg
    65941 tctgccaggg gcgttttctt tcagccagaa actcagcatc aacattccca tcgccagcag
    66001 agaacaaccg tcgaaagcgc gattgttggt caatgcaacc agccacaaaa aggccttact
    66061 ttcgaccagt ttctgattaa agaaataaaa aatatccgca tcaattggca accagaatcc
    66121 atgattaacg ggaatatacc aggaaagaaa cagcgcgagg ccgacaatat tcaacaacac
    66181 tatttgcggc aaatttttaa tcatattttc tctaattatc ttactgaaaa acgcaggcaa
    66241 ccttacgcgg tagtcgctaa acgaagcttc aacagcgcgc tctgcaaagc attccagtca
    66301 gcttcgctgc tggaaatcag ctcaatacgg ctgtccggtg gcgcaacgtt ttgcgtttca
    66361 atgtgcaggt catcgccctg acggttgatt cgtaccagcc cttcgggaat acgcagcacg
    66421 cctttgacgc gttccaccgg tgcaagtcgc gcccattcca gaatgccaat ggtgtcgaat
    66481 accgtatcag cgtcgaatat ccagccgcag gcctgatatc cttgcccgct gttcagactg
    66541 cgacgccagc gttgatgctc tggcaggctt aacgctgcta accctttttt cacgacatgc
    66601 tgatgagaat gcgcggcgct ggcgggcaac tcggctaaat tgcgacgcgg caaatccaga
    66661 agatgaccgt caactttccc atgctcactg tgaattaatt gtcgatcgcc accattttgc
    66721 tgccaccaac gctgtagcgc ttgctcactt tcgggcgtcg cacggtcgga tttattggcg
    66781 acaatgatgt ctgcggcagc cagctggtca cggaagtttc cattgctggc gcttttttcg
    66841 tccagcagca ggcgtggatc gagaatgcac aaggtggcgc gcagatctat ccacggttca
    66901 tagactggtg cggttaacag atcgaggatc tgtttcggat ggcccagccc ggtcggctct
    66961 atcaacaagc ggtctggttt tccctgacgc agtaaggtat tcaaccctac ctgcatgggt
    67021 aaaccattaa cgcagcacat gcagccgccg gggatctctt tcagcaatgc gccgctatcg
    67081 gcgagcaaag caccatcaat tccgacttcc ccaaattcat taaccagtac cgcccatttt
    67141 tcgttgggat ctttatgggc taacagatga agaatcgacg tggttttccc gctgccgaga
    67201 aaaccggtga tgaggttggt cctggtcaca acggctccgc aatactctgg taagttaact
    67261 gagcgttaat cctggctaaa aaaggcagaa aagagaaggg gagagcggac gaaggtgagc
    67321 ttcatccgct ttaaccgcag aaatcgttaa attttgaggg tgtttaatag cgcctgatgt
    67381 gcgccgaatt gtacgatttg ttgccaggct tgttcgatgg cctgcacaaa atgcgggtta
    67441 tctggcagat catcaccgaa aacttcacgc agggaaagca gggcggttac gcgttgttca
    67501 ctgctgctgc ccgcaacaag ttcgcgaatt ttatcgctaa gcggatcgcg aacatcaatg
    67561 gcatttccgg catcatcaac gccgctgacg taacgcatcc agccagcaac gcctaatgcc
    67621 agcaacgacc agtccgtttc gcgccccaga tgtatgcgaa tacctgccag catacgttgc
    67681 ggtaatttct ggctaccatc cattgcgatt tgccaggtct tatgtttcag cgccggatta
    67741 gcaaaacgtg caattaactt gtccgcatat tgtgttaaat cgacatcttt aatttgcagt
    67801 gtcggcgctt gctcatccag cattaatgtt ctggcggcat ggcgaaatgc gcgatcctgc
    67861 atgcaatcac tgatatgggc gaatcctgag aggtaaccca gataagcgag aaaagagtgg
    67921 ctgccattaa gcatccgcag tttcatctct tcccatggca ggacatcatt caccatttgt
    67981 acacctgcga cttcccaggc aggacgccca gcgacgaagt tatcttccac cacccactgg
    68041 ataaacggtt cgcagctaat cgcgcaggga tcattcaccc ccagatgctg gctgatttcc
    68101 accagtgatt cgtcggttgc agccggaaca atgcggtcga ccatggttcc cggaaaactg
    68161 acgtgttctt ttatccaccc ggcgagttct ggcgaacgtt tttctgccat tcccagcacc
    68221 gcgtttttca ccacatggcc attgtcggga atattgtcgc aggagagcac ggtaaacggt
    68281 gtaaggccgc gctcacggcg gcgtttcagt gcttcgacga gaatacccgg tgcggagtga
    68341 ggttcttcag gggtttgtag atcgtgaata atccgcggat tactggtgtc gagtgcaccg
    68401 gtggccgggt caatacaata gcctttttcg gtaatcgtca gggaaacaat tgccacctgt
    68461 ggctcgcaaa atttctcaat aattgccgct aaggaatcca gttttgcatt aaggcattcg
    68521 tgaacggcac cgacaattat cacctgattg ccgtccgcac ctttttccag cacggtatat
    68581 aaatggttct gtgcgcggag ctggctcatc agttgatcac cgctgaacaa gctgatttca
    68641 cagatccccc agtcgccgcc ctgggcattc agcacacgat cggtcagtaa cgcctgatga
    68701 gcgcggtgaa aggcgccaaa gccaaaatga acgatacgtg attgcaactg ctggcgatcg
    68761 tagcgtggag cgtgtacatg atgcgggagc gtaacggagg caattgtctt cataggagtc
    68821 acgtcttagt aacgataaat taacaatgac agtgtaaagt tatatgacag caattgaaat
    68881 tggtctggat tgttaatgcg atgaagtgtg agggcgatca atcaacgagt gaaaattgag
    68941 ggcgtaaggt gttcaggaag cgcaaaatag aagattggta taataaatta aaaaagggac
    69001 agcctgagct atcccttttc tgcatgcggc tgaagttagt cagcacgccc catataacgg
    69061 cgttcttcga tatggatacg aattttttcg cccgggctta agtattctgg tacctgaatc
    69121 accagaccag tgctcaatgt cgccggtttg ttacgggcgc tggcagatgc ccctttgatg
    69181 cctggtgcgg tttcaacgat ttccagatca acggtctgcg gcagctcaag cgccagcagt
    69241 tgaccgtccc aggtcagcac ctgcatgtcc ggcatgccgc cctctggcat aaacagcaac
    69301 tcttcttcaa tctgatcttt ggtgaaggta tacggggtat agtcttcttt atccataaag
    69361 acatattcgt tgccatcgac ataggagaag tcaacgtaac ggcgggtcag cgtcacggtg
    69421 tcaacgatat catcaccttt gaaacgctct tctactttca gcccggtacg gacatcagaa
    69481 aaacgcattt tgtacagcgt agcggcaccg cgggcagtgg gtgactgaat atcaatatcc
    69541 ttaaccagca gcagtttgcc gttgtaattc agtaccatac cttttttaat ttcgttcgct
    69601 cttggcatcg aaaaattcct gtagtcgaaa atgtcaaaaa tatcgcgaca aagtactcgc
    69661 gacgggcctt tcgggcaagt ggtattcgca cttttgctgg tgcaaaaaag gtggtactgt
    69721 gcgcgctcat caatccggtg gttaacctta agagaacaac gtatgaaatg ccgtccgggt
    69781 tgcggggcgt gttgcactgc cccttcaatt tccagcccta ttcccggtat gccagatggc
    69841 aagcccgcca atacgccctg cattcagctt gatgaacagc aacgctgtaa aattttcacc
    69901 tcgccactgc gaccgaaagt ctgtgcaggc ttacaagcca gcgctgaaat gtgcggtaac
    69961 tcgcgtcagc aggccatgac ctggcttatc gatctggaaa tgctgaccgc gccttaaaca
    70021 tctttaatcc gcagtaagca aaacagagtg gcgataatca tcaccatcgc aaaccagaac
    70081 acagcgtgat aattccagat ctcggcgacg atgcccgcca ctgatcctgc gatgatccag
    70141 cccacgcgcg acgtgttggt atagagcgtg gtggctgaac ccgcctgacc gggcatcaga
    70201 tcctgaaaat agagcatccc gatgccgccc agaatgccaa taaaaatagc atttagcagc
    70261 tgcaagccca acagaatgac aggtgaatgc gccatcagca ttcctgcgta aaaacagacg
    70321 ccacccacgg cagcaacgcg cattaagaaa cgcttaccca gacgtttggc gaaatatccg
    70381 gcaatcaaca tcgtcgggat ttccagcccg gcggcggtcc ccatcatcac accggccagt
    70441 ttctcgggaa gatgcagttc gttgataata aatagcggca tgttgatgat gtacaggctg
    70501 ttcgagcccc acatcaatgt acaaatgaca aacagcagta gcgtatcgcg acggttacgg
    70561 cgcggcgctt caaccgtgcc ggtcgccagc ggaagctctt tttgcatcga cggtaaaaac
    70621 agccacacca tcacgccgca aacaataaac gctaccgctg cgctcagata cattaccgta
    70681 aagctgaaac ccatcgctaa cgcataagcc agcggtgggc caatgaccca tgccagtgaa
    70741 acctgagcgc gtaaaaaaga gctgaacatc accgcctcac gtccggtttt gtcggcatgt
    70801 tcacgggcaa gggcaaacat ttgcgggtta gcggtcgagc caaagctgct aagaaagacg
    70861 ccaacgaata gcaaaacaaa gtagttgcga ttccaggcaa aaagggtgca ggccagcacg
    70921 cctaacaggc agcaaaagac aatcagcgat ttgcgatcgc cgcgcttatc agagcgcccg
    70981 gcgagaaact gacttaccag aatcccaatg acagcgctgc cggtaaagaa gaatcccacc
    71041 atcgccggac gggcatgtac ttcatcggta agaaaaatac tgagtgtcgg ggtttgcaga
    71101 gcgcccgcaa taccggtgag aaaggcaacg attaaaaacg ccgtcgaggt caggtcaaac
    71161 gatttcgcgc tggagactgc gggggagtta tgcatgctgg tcgatcactg gaagaggaag
    71221 acgcggagtt tacgctgctt gtcagaaaat aaacagacag cgaaatcaaa agcgccacga
    71281 ataatcaaaa tgccatttca ctgttgctga ttggctgctg acgctgctga aatgaaattg
    71341 ctgataacgg attttcccat cagcaattag gaaaaatggc aaaaaattgt gcagcacatc
    71401 aaacttttgc tcataacttt acggctttcc ttgcgtgctg aaacagaagt attatgcttt
    71461 cttgaaacgt ttcagcgcga tcttgtcttt aaccctaagc caggttggcg ctttttttct
    71521 catagaggct gaatcgtttc aattcagcaa gagaggagaa ctatgttcca gttatccgta
    71581 caggacatcc atccgggcga aaaggccgga gacaaagaag aggcgattcg ccaggtcgct
    71641 gcggcgctgg tgcaggccgg taatgtagca gaaggctacg tcaatggcat gctggcgcgc
    71701 gaacagcaaa cctcaacgtt cctcggcaat ggtattgcta ttccacacgg cactaccgac
    71761 acccgcgatc aggtgctgaa aaccggcgtt caggtatttc agttcccgga aggcgtcacc
    71821 tggggtgacg gtcaggtagc gtacgtggca atcggtattg ctgccagctc ggatgaacat
    71881 ctgggcctgc tacgccagct gacccacgta ctgagcgatg attccgttgc tgaacaactg
    71941 aagtcagcaa caacagcaga agaacttcgc gcattactga tgggcgaaaa gcagagtgag
    72001 cagctgaagc tcgacaacga aatgctgacg ctggatatcg tcgccagcga tctgctgact
    72061 cttcaggcgc tgaacgctgc gcgtctgaaa gaggcggggg cagttgacgc cactttcgtc
    72121 accaaagcca tcaatgaaca accgctgaat ctcggacagg gtatctggct gagcgatagc
    72181 gccgaaggca atctgcgtag cgcgattgcg gtaagccgtg cggcaaatgc ttttgatgtg
    72241 gacggcgaaa cggcagccat gctggtgagt gtggcgatga atgacgatca gcccatcgcg
    72301 gttcttaagc gtctcgctga tttattgctc gacaataaag ctgaccgctt gctgaaagcg
    72361 gatgcggcaa cgttgctggc gctgctgacc agcgatgatg cgccgaccga cgacgtgtta
    72421 agcgcggagt ttgtggtgcg caatgaacac ggcctgcatg ctcgtccagg taccatgctg
    72481 gtcaatacca ttaaacaatt taacagtgat attaccgtga caaaccttga tggtaccggc
    72541 aaaccggcaa acggacgtag tctgatgaaa gttgtggcac ttggcgttaa gaaaggtcat
    72601 cgcctacgct ttaccgccca gggtgcagat gctgaacagg cgctgaaagc aatcggcgac
    72661 gctatcgctg ctggtcttgg ggagggcgca taatgagcag acgtgttgct actatcaccc
    72721 ttaatccggc ttatgacctt gttggtttct gcccggaaat tgaacgcggc gaagtgaacc
    72781 tggtgaaaac caccggtctg catgcggcgg gtaaaggcat caacgtggcc aaagtattaa
    72841 aagacctggg aattgatgtc accgttggcg gcttcctggg taaagacaat caggatggtt
    72901 ttcagcaact gttcagcgag ctgggcattg ccaaccgttt ccaggttgta caggggcgca
    72961 cccgaattaa cgttaagctg acggaaaaag acggcgaagt gaccgacttc aacttctcgg
    73021 gttttgaagt cacccccgcc gactgggaac gctttgtgac tgattctctg agctggctcg
    73081 gtcagttcga tatggtctgt gtcagcggaa gcttaccgtc aggcgtcagc ccggaagcgt
    73141 tcaccgactg gatgactcgc ctgcgtagtc agtgtccttg cattatcttt gatagtagcc
    73201 gtgaagcgtt agtagcaggt ttgaaagcgg caccgtggct ggtgaaacct aaccgccgcg
    73261 agttggaaat ctgggcaggc cgtaaactgc ctgaaatgaa agatgtgatt gaagctgcac
    73321 atgcgctacg tgaacaaggt attgcgcatg ttgttatttc actgggtgcc gaaggcgcgc
    73381 tttgggttaa tgcctccggc gaatggatcg ccaaaccacc gtcagtcgat gtcgtaagca
    73441 ccgttggcgc aggggattct atggttggtg gcctgattta tggcttgctg atgcgtgaat
    73501 ccagtgaaca cacactgcgt ctggcgactg ctgttgcagc cctggcggta agtcaaagca
    73561 atgtgggtat taccgatcgt ccgcagttgg ccgcaatgat ggcgcgcgtc gacttacaac
    73621 cttttaactg acagcaggag aggcataatg aaaacgctgc tgattattga cgctaatctc
    73681 ggtcaggcac gcgcctatat ggcgaagacc ctgctgggcg cggcggcgcg aaaagcaaaa
    73741 ctggaaatca tcgacaatcc gaacgacgct gaaatggcga ttgttctcgg tgattccatc
    73801 ccgaacgaca gcgcgctgaa cggtaaaaat gtctggcagg gcgatatttc ccgggcagtt
    73861 gcgcaccctg agctgttcct gagtgaagcc aaaggccatg cgaaacctta cactgcgccg
    73921 gtcgctgcga cagcaccggt tgacgccagc ggcccgaaac gcgtagttgc ggtgactgct
    73981 tgcccgactg gcgtagcaca cacctttatg gctgctgaag ccattgaaac cgaagcgaaa
    74041 aaacgtggct ggtgggtgaa agttgaaacc cgtggttctg ttggcgcggg taatgcaatc
    74101 actcccgaag aagtagccgc agcggatctg gtgattgtgg cggcagatat cgaagtggat
    74161 ctggcgaaat ttgctggtaa accgatgtat cgcacctcta ccggtctggc gctgaagaaa
    74221 accgcgcagg aactggataa agcggttgct gaagcaacgc cgtatgaacc ggcgggcaaa
    74281 gctcaaacgg cgaccactga aggtaagaaa gagagtgcgg gcgcttaccg tcacttgctg
    74341 acgggcgttt cttacatgct gccgatggtc gttgctggtg gtctgtgtat cgcgctttct
    74401 tttgcttttg gtatcgaagc gtttaaagag ccgggtacgt tggcagcggc gctgatgcag
    74461 attggcggtg gttcagcctt tgcgctgatg gtgccggtac tggcaggtta tattgccttc
    74521 tccattgccg atcgtccggg cctcacgccg ggtctgattg gcggtatgct ggctgtcagc
    74581 accggttctg gcttcattgg cggtattatt gcgggcttcc tggctggtta cattgcgaag
    74641 ttaatcagta cgcaactgaa actgccacag agtatggagg cgctgaaacc aatcctgatc
    74701 attccgctaa tttccagtct ggtggtcggt ctggcgatga tctacctgat cggtaaacca
    74761 gttgctggca ttctcgaagg gctgactcac tggctgcaga ccatggggac tgcgaatgcg
    74821 gttctgctgg gggcgatcct cggtggcatg atgtgtactg acatgggcgg tccggtaaat
    74881 aaagcagcgt acgcgttcgg tgtgggtctg ctgagtactc aaacctatgg cccgatggcg
    74941 gcgattatgg cggcaggtat ggtgccaccg ctggcaatgg gtctggcaac aatggtggcg
    75001 cgtcgcaaat tcgacaaagc gcagcaggaa ggtggcaaag ccgctctggt attgggactg
    75061 tgcttcattt cggaaggtgc aattccgttt gctgctcgtg atccgatgcg tgtgctgccg
    75121 tgctgtatcg tgggtggggc gctgactggc gcaatctcaa tggcgattgg tgcgaaactg
    75181 atggcaccgc acggtggtct gtttgttctg ctgatccctg gcgcgattac gccggtactg
    75241 ggttacctgg tagccattat tgccggtacg ctggtggcgg gtctggccta tgccttcctg
    75301 aaacgcccgg aaacacaaat agtagaaaaa aacgcataat ttatcttcat tatcggggat
    75361 gagacatctc tgccccgatg atgacaaacg caaaattgcc tgatgctcta tgcttatcag
    75421 acctacatga accctgcaat atattgaatt tttgcgcttt tgtaggtcgg ataaggcgtt
    75481 tacgccacat ccaggatgaa caaagcgcgc gttgtcaaca atctggaggg cagaaacatc
    75541 tctgcccttt ttcttgcctg ccatattgtg tgttacacat cacaattttc tcttttgttg
    75601 ctgcataaat agacaaactt tgtgaccgcc ttcatatctg gccgatttcg ttttttctga
    75661 tcgatttaca ttacgttaaa tatgcttatt atgaacatgt gtttaaatat gaacacgtgc
    75721 tctaatagtc ttattgactg taatgactat tttacccaat ttcttcgttg gcaatttatt
    75781 gccagggggc gtgctatgcg cgaaaaggac tacatagtaa ttattggttc ggcgaatatt
    75841 gatgtggctg ggtattcaca tcatccattg aattatgcgg attcgaatcc cggaaaaatt
    75901 aaatttaccc caggtggcgt gggaaggaat atcgctcata atctggcgtt actggggaaa
    75961 aatgcctggc ttttaagtgc agtaggtggt gatttttatg ggcaatcatt actggcgcaa
    76021 actaatcaat ccggtgttta tgtcgataaa tgcttaattg ttccgggtga gaatacatcc
    76081 agctatttat cactgctcga taatacagga gaaatgcttg tcgcgataaa tgatatgagt
    76141 attagtgact gtatttctgc agaatttctt gcccagcatc aggagtttat tcgcggtgca
    76201 aaggttattg tcgcggattg caaccttagt gaagaggcgc tggtctgggt tctggaaaat
    76261 agcggggaaa cgcctgtatt tattgatccg gtatcggcat ggaaatgcgt caaaatccgc
    76321 gatcatctga gcaaaatcca tacgttaaaa cctaaccgtc ttgaagccga aacgttgagc
    76381 ggaattgcac tttccggacg tgaagatgtc gcaaaggtcg ccgcctggtt tcatcaacac
    76441 ggcctgaacc gcctggtgct gagcatggga ggggatggcg tttactacag tgatatcaac
    76501 ggtgaaagtg ggtggtcggc ccctattaaa acgaatgtca tcaatgttac tggggcaggc
    76561 gacgccatga tggcggggct ggcctcctgt tgggtagacg gtatgccgtt tatcgattct
    76621 gttcgatttg cgcagggatg ttcgtcaatg gcacttgcct gtgaatatac caacaaccct
    76681 gaattatcaa ttgccaatgt tagatcgtta gtggagaaca cagaatgtct gaattaactc
    76741 tgtcccctga attattacaa atatccgctg aagtacagga tgctttaaaa aataaaaaac
    76801 cggttgttgc gctggaatcg accataattt ctcacggaat gccattccca caaaatgccc
    76861 aaaccgcaat tgaagtagaa gaaactattc gtaaacaggg cgcagtacca gccactatcg
    76921 ccattattgg cggtgtgatg aaagtgggct taagtaaaga agaaatcgaa ttgctgggcc
    76981 gtgaaggaca taacgtgacc aaagttagtc gtcgcgattt accttttgtt gttgccgccg
    77041 gaaaaaatgg cgcaaccact gtggcttcaa cgatgattat tgcggcgctt gccggaatta
    77101 aagtatttgc caccggggga attggtggtg tgcatcgcgg ggcggaacat accttcgata
    77161 tttctgccga tttacaggaa ctggcaaata ccaatgtcac tgttgtttgt gcgggggcaa
    77221 aatctattct cgatttagga ttaacaacag aatatttaga aaccttcggt gtaccgttaa
    77281 ttggttatca gacaaaagcg ctgcctgcgt ttttctgccg aaccagccca tttgaagtca
    77341 gcattcgtct tgacagtgcc cgcgaaattg ctcgcgcgat ggcagtgaag tggcaaaccg
    77401 gtttgaacgg cggcctggta gtggcgaatc cgatcccgga acagtttgcg atgccagaag
    77461 aaaccatcaa tgcagcaatt gatcaagccg ttgctgaagc cgaagaacag ggtgttattg
    77521 ggaaagagag tacaccgttc ctgctggcgc gtgttgcgga gctaacaggc ggtgatagcc
    77581 tgaaatccaa tattcaactg gtctttaata acgccattct ggcgagcgaa attgccaaag
    77641 aatatcagcg tctcgtgggt taatttctgg cgggcagaaa gccgtcgccc gtactcatca
    77701 aacataccaa aacctggcgc tgacgccggg tttactggca tgaagggaaa atcattatgg
    77761 atataatgag aagtgttgtg gggatggtgg tattgctggc aattgccttt gtgttgtcgg
    77821 taaataaaaa gagcatcagc ttgcgcacgg ttggcgctgc gctgctgctg caaattgcca
    77881 ttggtggcat catgctctat tttcccccgg gaaaatgggc agtagagcag gcggcattag
    77941 gcgtccataa agtgatgtcc tacagtgacg caggaagtgc ctttattttt ggttcgctgg
    78001 tcggtcccaa aatggatgtt ctgtttgacg gtgcgggctt tatcttcgcc tttcgcgtac
    78061 tcccggcgat tattttcgtt accgcgctta tcagcttgct gtactacatt ggcgtaatgg
    78121 ggctgctgat tcgtattctt ggcagtattt ttcagaaagc cctcaacatc agcaaaatcg
    78181 aatcttttgt cgcagtcacc actattttcc tcgggcaaaa tgagatcccg gcgatcgtta
    78241 aaccttttat tgatcgcatg aatcgcaacg agctatttac ggctatttgt agcggcatgg
    78301 cgtctattgc gggttcgatg atgattggct atgccggaat gggcgtgccg attgactatt
    78361 tgttagccgc ttcgctgatg gctattcctg gcggtatcct gtttgcacgt attcttagtc
    78421 cggcgacgga accttcgcaa gttacgtttg aaaatctgtc gtttagcgaa acaccgccaa
    78481 aaagcattat tgaagctgcg gcgaacggtg caatgaccgg gctgaaaatc gccgccggtg
    78541 tggcgacggt ggtaatggca tttgtggcaa ttattgcgct gatcaatggc attattggtg
    78601 gagttggcgg ctggtttggt tttgccaatg tctctctgga aagcattttc ggctatgtgc
    78661 tggccccgtt ggcatggatt atgggggtgg actggagtga tgcaaatctt gccggaagtt
    78721 tgattgggca gaaactggcg attaatgagt ttgttgctta tctcaatttc tcgccctatc
    78781 tgcaaacgag cggcacgctg gatgtcaaga ccattgccat tatctcgttc gccctctgtg
    78841 ggtttgcaaa ctttggttct atcggtgttg tcgttggcgc attttcggct atttcgccaa
    78901 aacgtgctcc agaaatcgcc cagcttggtt tacgggcgct ggcagcagca acgctttcca
    78961 acctgatgag tgcgactatt gccgggttct ttattggtct ggcgtaatgc tcgatttgta
    79021 gaccggataa aacgtattaa gcgttgcatc cggcaatcgc gctattgcaa ataattttta
    79081 ctgcatcatc ccggagaatt tattctccgg gtccatctcc agcgccagtc ctgacaactg
    79141 ctttctgttt ttaatgagat accctttctt gcttttagtt aataaaccgt cgtgaatgaa
    79201 ttgcgcgaga acatataaaa gatgtcgata agaaacgcct aaatactctg ccgcttgcgt
    79261 atgcttttcg tgataaagat caccttcctg cgagagtaat ataaaagctg ccaggcgatt
    79321 aactaacgga aatgattgat tctgagttaa agaaacaata ttacgataat ttttatgact
    79381 taaggtgacg cagagttttc gtaaaaatag cgtgtcgttt aataaccgcg ggcggtaatg
    79441 tttcataggg agcgcaaggc accaacactc ttcaatagcc tgcaccgcac gcggttcatg
    79501 gtctttgtcg attaactcaa tctcgccaat aaaacagggg gcggcaaaga aatcgatcag
    79561 cgacacgcga ccattagcta gcgtggcgta aagcctggcg cggcctcgcg tcaggtaaaa
    79621 cagccaggac ggctgttgcc cttcctgcac aatgtagtca cgcgctaaaa aatgaaacag
    79681 ccgcgtatcg gctgaaacat ccgttaaaaa gcaatcctta aacgcggatt cactcatcaa
    79741 ttgctgctta agatcattat tgtggatttc tttcacgatg tttatccgct atgagatttc
    79801 tcatatttag catacgtacg cggttggtaa gattcaatca tcggcccggt cgaattttct
    79861 ttgctgtaga aaaaataacg caactggaaa cagaggaaat aaacaatgga aaagagaaaa
    79921 attattctgg attgtgatcc gggtcatgat gatgctattg ctataatgat ggcggcgaaa
    79981 catccggcaa tagatttatt aggcatcact attgtagcgg gtaatcagac gcttgataaa
    80041 acattaatta atggcctgaa tgtttgccag aaactggaga ttaatgttcc ggtttatgcg
    80101 gggatgccgc aacccattat gcgtcaacaa atcgttgccg ataatattca cggtgaaacc
    80161 ggactggatg gcccggtatt cgagccgctg acccgccagg cagaaagtac ccacgcggtg
    80221 aaatacatca ttgataccct gatggcaagc gatggcgata tcactctggt gccggttggt
    80281 ccgctttcaa atatcgcggt ggcaatgcgt atgcaacccg cgatcctgcc caaaatccgt
    80341 gaaattgtgc taatgggcgg cgcttacggt acaggcaact tcacgccatc tgccgagttc
    80401 aacatctttg ctgacccgga agcagcccgc gtggtgttca cctctggcgt tccattagtg
    80461 atgatgggcc tcgatctcac caaccagacc gtttgcaccc cggacgtgat tgctcggatg
    80521 gaaagggcag gcggccctgc cggagagctg ttcagcgaca tcatgaactt cactctcaaa
    80581 acgcagttcg aaaactacgg cctggctggc ggcccggtgc acgacgccac ctgcatcggt
    80641 tatctgatta accctgatgg cattaaaacc caggagatgt acgtcgaagt ggacgtcaac
    80701 agtggccctt gctatgggcg caccgtctgc gacgagctgg gcgttcttgg caagcccgcc
    80761 aataccaaag tcggcatcac tattgatacc gactggttct ggggcttagt cgaagagtgc
    80821 gtgcgcggct acatcaaaac ccattaagcg ttgataacaa gccgggccga tagcgcaaga
    80881 tgcaggcccg actatttctg atgggcagaa agccgtcgcc caatatgaca tgaagagata
    80941 atcactatgg atgtcatgag aagtgttctg ggaatggtgg tattgctggc aattgcattt
    81001 ttgctgtcag taaacaagaa gaagatcagc ctgcgtaccg ttggcgcggc gttagtgtta
    81061 caggttgtga ttggcggcat tatgctttgg ttaccgccag ggcgttgggt cgctgaaaaa
    81121 gtcgcttttg gcgtgcataa agtgatggcg tacagcgacg cgggtagcgc atttatcttc
    81181 ggttcgctgg tcgggccgaa aatggacacg ctgtttgatg gcgcaggatt tatctttggt
    81241 ttcagagtat taccggcaat tatcttcgtt acagcactgg tgagtattct ctactacatc
    81301 ggtgtgatgg ggattttaat tcgcattctc ggcggtatct tccagaaagc gttaaatatc
    81361 agcaagatcg agtcattcgt cgcggtcact accattttcc tcgggcaaaa cgaaattccg
    81421 gcaatcgtca aaccctttat cgatcgtctg aatcgcaatg aattatttac agcgatttgt
    81481 agtggcatgg cctcgattgc tggttcgaca atgattggtt acgccgccct gggcgtacct
    81541 gtggaatatt tgctggcggc atcgttaatg gcgatcccag gcgggatctt gtttgcccgc
    81601 ctgttaagcc cggctacgga atcttcgcag gtttccttta ataacctctc tttcaccgaa
    81661 acaccgccaa aaagcattat tgaagccgct gcgacagggg caatgaccgg gctgaaaatc
    81721 gccgccggtg tagcgacagt tgttatggca tttgtcgcca tcattgcgtt aattaatggt
    81781 attatcggcg gcgttggcgg ctggtttggt tttgcacatg cctcgctgga gtccatttta
    81841 ggttacctgt tggccccatt ggcgtgggtg atgggggttg actggagtga tgcaaatctt
    81901 gccgggagtt tgattgggca gaagctggcg atcaatgaat ttgtcgctta tctcaatttc
    81961 tcgccatatc tgcaaacggg tggcactctg gatgctaaaa ccgtggcgat tatttctttc
    82021 gcgttgtgcg gtttcgctaa ctttggttct atcggggtgg tggtgggggc gttttctgcg
    82081 gttgcgccac accgtgcgcc ggaaatcgcc caacttggtt tacgcgcgct ggcggcggcg
    82141 acactttcta acctgatgag tgctactatt gcaggattct ttattggttt agcgtagtgc
    82201 gcaatttatg agccggataa gatgcggtca agcgtcgaat ccggcaacat tgttacacca
    82261 ttggcactaa tgaaagcgcg ttatcggcag acagggtagg gttgtttaag ctgccgctgg
    82321 cgcgcgaaat tgccgcgcag gctaccgcaa aacgggcgct gtcgcggaaa ctgtatcctt
    82381 caagaaagct atataccagg cccgccataa aaccatcgtc agcaccaaaa ctgtctactg
    82441 tcgtatgcgc tggcgcggtc agcaaaaatt gttctccatc cttatcgctg caaaatacag
    82501 attcatcttt cagataaaca aaaatgcgtt taacaccttg ttgatgcagc gaatttacag
    82561 ctctgatgcg atcgttgtcg tctttaatcg gttgccccca caaaatttcc agttcatttt
    82621 gtgttggttt cagagtgtgg atccggctgt accagttttt tactttgttc gctttaaatt
    82681 cggaaacggt atcgacaaac atcggaattt catcagcaat ggtaaagacc cactccaggg
    82741 cttcaggtgt gagattacaa tcagccagca ccacaccagc atggcgaatc aagtcccgtg
    82801 aagtattgag cagttgaggc gttagctgtt gcagaatatg tgtgtcattg attgccagga
    82861 tagtttcttc ctgcttatta gcgatagcga gataagttgc agtgctgtgt ccatgcagac
    82921 gaatgcagtt tgaaacgttc acgcccgcgc ggcgcgtttc ttccagtaat gtctcgccgt
    82981 aaaaatcgtt gccaatagct gatattaaat gcacatcccg accaagcaga gccaggttat
    83041 gcgcgatatt acgtccgacg ccgcctgcgg aacagtgaac agaacctgga tgagaggctg
    83101 cttgcgggta acggatatcc gccattccgc gaatatccat attgattgca cccacaacca
    83161 cacagtaatc ctgctcggta aggatatatc ctttgccttt aatcaaaccc ttgcgcatca
    83221 aatccataat atgagcggca acacgtgagc ggctgatttg cagaatatcg gcgatttcat
    83281 tctgttgaat cagcgggtta cgccgtaaaa ttttaagaat ctgcttttcc ctgtcgttca
    83341 tcgatcaggc caccgctttt tcagtttgtt gcgctttcag ccaggcgatc tcttctgccc
    83401 agatatccgg gttgatggtt tcaaggatca gcggaatgcc gtcgaaacgg tcgtcctgca
    83461 tgatccagcg gaacgcatca tgaccgatat tgccttcacc gaggctatga tggcggtcaa
    83521 cgcggctgcc aaaggtgctt ttcgcatcgt taaggtgcat cccgcgcaga tacttaaagc
    83581 caacaatacg ggcaaaatcc gcgaacgttt tctcgcattc ggctggagta cgcaaatcat
    83641 acccggcagc gaaagcatgg caggtatcaa tgcagacgcc gacacgggat ttatcttcca
    83701 cgccgtcgat aatcgccgcg agatgttcga atttaaaccc taagttactg ccctgaccgg
    83761 cggtgttttc aatcaccgct gttacacctt gagttttatc cagcgcaatg ttgatggatt
    83821 cggcaatacg cgcaaggcaa tcctcttctg aaatctgcat cagatggctg ccagggtgga
    83881 agttgagcaa agaaagcccc agttgttcgc aacgctgcat ttcatctata aaggcatcgc
    83941 gcgatttttc cagagcttca gtgaccggat gtccgaggtt aatcagatag ctgtcgtggg
    84001 gaagaatttg cgccgatgtg tagtgatatt tttcacaggc cgctttgaat tcatcgatgg
    84061 tttgcgtcgt gagcggtgcg gcacgccact gacgttggtt tttggtgaac aaggcaaacg
    84121 cggttgcgtc gatttcggcg gcgcgaattg cggcatttgc cagaccgcca gcagcactaa
    84181 cgtgcgctcc aatgtatttc atgcgaggac tcctgttaaa cccgctggag gaaaacggta
    84241 atgatagcgg gttaacagga gcaagatgta gtggtttatg cgatgacgct ttgaatcaca
    84301 tagttaatcg caccaccacc aacaatcagc caggcaaaca gtaccagtgc catcagcaga
    84361 ggtttcgccc cggctttttt cagcgcgctg acgtgagtgg tcagacccag cgccgccatc
    84421 gccattgcca gcaggaaggt atccagcgtt accagcatgt tcaccacgct ctgcggtaac
    84481 aggtggaacg agttaaagat ggcaacgacg atgaacaata tggcaaacca cggaatagtg
    84541 attttgcttt tctcgccgct gttcgcccca gacagctgtt taacacgcgc cgccagcagg
    84601 atgaggaacg gagccagcat catcacgcgc agcattttgg aaataactgc tgcgttttcc
    84661 gcatccgggc tgatggcatg acctgccgcc accacctgcg ccacttcgtg cacagtagaa
    84721 ccaatgtaga taccgaaagt ttccggacta aaccattgag acatcagcgg atatatcgcc
    84781 gggtagagga aaatcgcgac ggtcccgaag ataacaacgg ttgcaacagc cacggttact
    84841 ttactggctt ccgctttcac taccggctca gtcgccagta ccgcggcagc accacagata
    84901 ctgctaccgg caccgatcaa ccagctggtg tgcttatcca gaccaaacac tttctgcccc
    84961 aggaagcaag ccagcaggaa ggtactggac agcgtcagca cgtcaatgat gatcccactg
    85021 ataccgacat cggcaatttg cgagaacgtc agacggaagc cataaagaat gatacccaga
    85081 cgtaataaat attgcttggc aaacagcaca ccaccgtcac agcttttcca gatgtgcgga
    85141 tagatggtgt tgcctaaaac catccccaac aagattgcga gggtgagggc actaaacccg
    85201 gcacccgcaa ccgcgggaat ggaaccaccc cacagggcga ccccggtgat aactgcactc
    85261 agggctaacc ccggaataaa atgccacagt gtacgatgtt gtttctgtaa ggtgatattc
    85321 gtcataaccc tctcctttaa ccgggcataa ggttacgact aactggttta aaaataaaat
    85381 tgattatata tttataatta atctttataa gtggtaagcg actatgcaca tcaccctccg
    85441 gcagttggaa gtttttgcag aagtattgaa aagtggatca accacccagg cgtcggtgat
    85501 gctggcgttg tcgcaatcag cagtgagcgc agccttgacc gacctggaag ggcagcttgg
    85561 cgtgcaactg tttgatcgcg tggggaaaag actggttgtt aatgaacacg ggcggctgct
    85621 ctatccgcgt gcgttggcat tgcttgaaca ggcggttgaa atcgaacaac tgtttcgcga
    85681 agacaacggc gcgattcgta tctatgccag tagtaccatc ggtaactaca ttctgcctgc
    85741 agttatcgcc cgttatcgcc atgattatcc gcagttgccg attgaactta gcgttgggaa
    85801 cagccaggac gtgatgcaag cggtgctgga tttccgcgtt gatattggtt ttattgaagg
    85861 accgtgccac agcactgaaa ttatttctga accgtggctg gaagacgagc tggtggtttt
    85921 cgccgcgccg acttcgccgt tggcccgtgg tccggtcacc ttagagcagc tggccgctgc
    85981 gccgtggatc ctgcgtgaac gcggttccgg cacgcgggag attgtcgatt atctattgct
    86041 gtcacattta ccgaagtttg agatggcgat ggaattaggt aactccgagg caatcaaaca
    86101 tgcggtgcgt catgggttgg gaattagttg cctgtcgcga cgggtgattg aagatcaatt
    86161 gcaggcaggc acattaagtg aagttgcggt ccctctgccg cgcctgatgc gtacgttgtg
    86221 gcgtatacat catcggcaaa aacacctttc caacgcgcta cggcgctttc tggactattg
    86281 cgatcccgcg aatgtaccgc gttaagttgc tgtacaagaa catgctggtg ctgtgtcgat
    86341 ttcgtgacgc agcgccctca gcatgcattc gccagaaaag agattggctg ctttacttat
    86401 aatccctggg cgatcatgaa ggtgtcttat aaccgtgtat ttctgccgga aggattgcca
    86461 atcgtctgct acaatcgcgc ctcattttta agatggatag catttttgta tggtttccga
    86521 aactaaaacc acagaagcgc cgggcttacg ccgtgaatta aaggcgcgtc acctgacgat
    86581 gattgccatt ggcggttcca tcggtacagg tctttttgtt gcctctggcg caacgatttc
    86641 tcaggcaggt ccgggcgggg cattgctctc gtatatgctg attggcctga tggtttactt
    86701 cctgatgacc agtctcggtg aactggctgc atatatgccg gtttccggtt cgtttgccac
    86761 ttacggtcag aactatgttg aagaaggctt tggcttcgcg ctgggctgga actactggta
    86821 caactgggcg gtgactatcg ccgttgacct ggttgcagct cagctggtca tgagctggtg
    86881 gttcccggat acaccgggct ggatctggag tgcgttgttc ctcggcgtta tcttcctgct
    86941 gaactacatc tcagttcgtg gctttggtga agcggaatac tggttctcac tgatcaaagt
    87001 cacgacagtt attgtcttta tcatcgttgg cgtgctgatg attatcggta tcttcaaagg
    87061 cgcgcagcct gcgggctgga gcaactggac aatcggcgaa gcgccgtttg ctggtggttt
    87121 tgcggcgatg atcggcgtag ctatgattgt cggcttctct ttccagggaa ccgagctgat
    87181 cggtattgct gcaggcgagt ccgaagatcc ggcgaaaaac attccacgcg cggtacgtca
    87241 ggtgttctgg cgaatcctgt tgttctatgt gttcgcgatc ctgattatca gcctgattat
    87301 tccgtacacc gatccgagcc tgctgcgtaa cgatgttaaa gacatcagcg ttagtccgtt
    87361 caccctggtg ttccagcacg cgggtctgct ctctgcggcg gcggtgatga acgcagttat
    87421 tctgacggcg gtgctgtcag cgggtaactc cggtatgtat gcgtctactc gtatgctgta
    87481 caccctggcg tgtgacggta aagcgccgcg cattttcgct aaactgtcgc gtggtggcgt
    87541 gccgcgtaat gcgctgtatg cgacgacggt gattgccggt ctgtgcttcc tgacctccat
    87601 gtttggcaac cagacggtat acctgtggct gctgaacacc tccgggatga cgggttttat
    87661 cgcctggctg gggattgcca ttagccacta tcgcttccgt cgcggttacg tattgcaggg
    87721 acacgacatt aacgatctgc cgtaccgttc aggtttcttc ccactggggc cgatcttcgc
    87781 attcattctg tgtctgatta tcactttggg ccagaactac gaagcgttcc tgaaagatac
    87841 cattgactgg ggcggcgtag cggcaacgta tattggtatc ccgctgttcc tgattatttg
    87901 gttcggctac aagctgatta aaggaactca cttcgtacgc tacagcgaaa tgaagttccc
    87961 gcagaacgat aagaaataag tttcctccct tccttgctaa gccctctcaa ccgagagggc
    88021 tttttcaatt ccatttccct gacaaatcat gcggatataa aatttaacat ttggattgat
    88081 aattgttatc gtttgcatta tcgttacgcc gcaatcaaaa aaggctgaca aatcagaggc
    88141 tgttccggct ttctgggatg atcacctgca tacaaataag tccaccgcga tgctgccgta
    88201 cgcaagggga cgtgaagaag atgtgagcga taacccattt tattttcgta gttacctcat
    88261 ggagatatgg aatgtttagg ttgaaccctt tcgtacgggt cgggctgtgt ttgtccgcta
    88321 tttcttgtgc atggcctgtg ttagcggtcg atgatgatgg cgaaacgatg gttgtcactg
    88381 catcttccgt tgaacaaaac ctcaaagatg cacccgccag tatcagcgtc attacccagg
    88441 aagacctgca gcgaaaaccg gtacagaatc tgaaggatgt cctcaaagaa gtgcctggcg
    88501 tacaactgac gaacgaaggg gataaccgta agggcgttag tattcgtggt ctggacagca
    88561 gctacaccct gattctcgtc gacggtaaac gcgttaactc ccgcaatgcc gtcttccgcc
    88621 acaatgattt cgatctgaac tggatcccgg tcgattccat cgaacgtatt gaagtggttc
    88681 gtggcccgat gtcgtcgcta tacggctccg atgcgctcgg cggtgtagtg aatatcatca
    88741 ccaaaaaaat cggtcagaaa tggtcgggta ccgttaccgt cgataccacc attcaggaac
    88801 atcgcgatcg cggtgatacc tataacggtc agttctttac cagtggacca ttaattgatg
    88861 gtgtgctggg aatgaaagct tacggcagcc tggcaaaacg tgaaaaggat gacccgcaaa
    88921 actcaacgac caccgatacc ggagaaacgc cgcgtattga aggattctcc agccgcgacg
    88981 gcaatgtcga atttgcctgg acaccgaatc aaaatcacga ttttactgcc ggatacggtt
    89041 tcgaccgtca ggatcgtgat tccgactcgc tggacaaaaa ccgcctggaa cgccagaact
    89101 actccgtcag ccataatggg cgttgggatt acggcaccag cgaactgaaa tactacggtg
    89161 agaaagtcga gaacaaaaac cctggcaaca gcagcccgat aacttccgaa agcaatgcgg
    89221 tcgacggcaa atacacgttg ccgctgacgg caattaatca gtttctcacg gttggcggtg
    89281 aatggcgtca cgacaaactt agcgatgcgg tgaacctgac cgggggaacc agctccaaaa
    89341 cgtctgccag ccagtacgcg ctgtttgtgg aagatgaatg gcggatcttc gagccgctgg
    89401 cgctgacgac cggcgtgcgt atggacgatc acgaaaccta cggtgaacac tggagtccgc
    89461 gtgcctacct ggtttataac gccaccgaca ccgtaacggt gaaagggggc tgggcgacgg
    89521 catttaaagc accttctctg ttgcaactta gccctgactg gacgagcaat tcctgccgtg
    89581 gcgcatgtaa gattgtgggt agcccggatc tgaaaccaga aaccagcgaa agttgggagc
    89641 tggggcttta ctacatgggt gaagaaggct ggctggaagg ggttgaatcc agcgttaccg
    89701 ttttccgtaa cgatgtgaaa gatcgtatca gcatcagccg tacgtctgac gtcaacgctg
    89761 caccgggcta ccaaaacttt gttggttttg agacgggcgc taacggacgg cgcataccgg
    89821 tatttagcta ctacaacgtt aacaaagctc gtattcaggg cgtggaaacc gaactgaaaa
    89881 ttccgttcaa cgatgaatgg aaactgtcga tcaactacac ctacaacgat ggtcgtgatg
    89941 tcagcaacgg cgaaaacaaa ccgctatccg atctgccgtt ccatactgct aacggtacgc
    90001 tggactggaa accgctggcg ctggaagact ggtcattcta tgtttctggt cactataccg
    90061 ggcagaaacg cgccgacagc gcgacggcta aaacaccggg cggttatacc atctggaata
    90121 ccggcgcggc ctggcaggtg actaaagacg tcaaactgcg cgcaggcgtg ctgaaccttg
    90181 gcgacaagga tctcagtcgt gacgactaca gctataacga agacggacgt cgttacttta
    90241 tggcagtgga ttatcgcttc tgatgagaag atgcccggcg aaccgggcgg actttcactt
    90301 cagtaaatac tgcgcatgga agcgcaggtg atcctctata aaagaggcga tgaagtagta
    90361 actgtgatca tatcccggct gaatacgcag cgtcatcggc cacgctttct ggcgcgcggc
    90421 ttctgccagt accgcaggtt gcaactggtc ggcaagaaac tgatcattat cgccctgatc
    90481 gataagcgtc gggatcgcat cctgcgcgtt actggcatac atcagcgcgc aactgtccca
    90541 ttccagccat gcatttttgt cctcacctaa atagctgcta aacgctttga ttccccacgg
    90601 gacgctgcac ggattcacaa ttggcgcaaa ggccgaaacg ctggtgtatt tacccggatt
    90661 tttcagcgcc ataatcagcg caccgtgacc acccattgaa tgaccgctaa tggcgcagcg
    90721 gtcgctgaca ttaaattgcg actgaaccag cgccggtaat tcatcgcgca gataatcata
    90781 catccggtaa tgcgtcgccc acggcggttg cgtggcgtta agataaaacc ccgcgccctg
    90841 gcctaaatcg tagccatcat cgttggcaac ctgttcgccg cgcgggctgg tgtctggcat
    90901 caccagtaca atccccagtt ctgccgccac gcgctgggca cccgccttga tggtgaagtt
    90961 ctcgtcattg caggttaatc cggaaagcca gtacagcact ggtggcgggg tgtgatcacg
    91021 aggtggtggg agaaagatac tgaacgtcat cggacagttt aaggtactgg agtcgtgtcg
    91081 ccagcgttgc tgccagcctt caaaacagcg gtgctcttcg agcatttcca tgcgtggctc
    91141 cttgttgtgt tgtttgcaat ttcttcatca taccgtttat tcaatgtgct gtgagtaact
    91201 ttcacttccg tatttgcata acgatgtttt aacatctgct gatgaaaggc agcggcaatt
    91261 acaataatta tcgctgtgaa tactggatta tgtgcgccgc ctcacgcaca ataatcaagc
    91321 tgtaaatcag cttaataact ttgcccccac gcagggcgga ggcgtcacac ctgcaggaga
    91381 aatcataaat gccatcactc agtaaagaag cggccctggt tcatgaagcg ttagttgcgc
    91441 gaggactgga aacaccgctg cgcccgcccg tgcatgaaat ggataacgaa acgcgcaaaa
    91501 gccttattgc tggtcatatg accgaaatca tgcagctgct gaatctcgac ctggctgatg
    91561 acagtttgat ggaaacgccg catcgcatcg ctaaaatgta tgtcgatgaa attttctccg
    91621 gtctggatta cgccaacttc ccgaaaatca ccctcattga aaacaaaatg aaggtcgatg
    91681 aaatggtcac cgtgcgcgat atcactctga ccagtacctg tgaacaccat tttgttacca
    91741 tcgatggcaa agcgacggtg gcttatatcc cgaaagattc ggtgatcggt ctgtcaaaaa
    91801 ttaaccgtat cgtgcagttc tttgcccagc gtccgcaggt gcaggaacgt ctgacgcagc
    91861 aaattcttat tgcgctacaa acgctgctgg gcaccaataa cgtggctgtc tcgatcgacg
    91921 cggtgcatta ctgcgtgaag gcgcgtggca tccgcgatgc aaccagtgcc acaacaacga
    91981 cctctcttgg tggattgttc aaatccagtc agaatacgcg ccacgagttt ctgcgcgctg
    92041 tgcgtcatca caactgatta aaaggcagga accatggagc gcaacgtcac gctcgatttt
    92101 gttcgcggcg tcgccattct ggggatcctg ctattaaaca tcagcgcctt tgggctacca
    92161 aaggcggctt atctcaatcc cgcctggtac ggtgctatta cgccgcagga tgcatggacc
    92221 tgggcatttc ttgatctcat cgcccaggtg aaattcctca cgctttttgc gctgctgttt
    92281 ggtgctggac tgcaaatgtt gctgccccgt ggcagacgct ggatccagtc gcggttaacg
    92341 ctgttagtct tattgggctt tattcacggt ttattgttct gggacggcga tattcttctg
    92401 gcttacgggc tggtgggctt aatctgctgg cggctggtgc gcgatgcgcc atcggtaaaa
    92461 agcctgttta ataccggcgt catgctttat ctggtggggc ttggcgtttt gctgttattg
    92521 gggctgattt ccgacagcca gaccagccgc gcctggacgc cggatgcatc ggctattttg
    92581 tatgaaaaat actggaagct tcacggcggc gttgatgcga tcagtaatcg tgccgatggt
    92641 gttggcaaca gtttactggc actgggcgca cagtatggct ggcaactggc tgggatgatg
    92701 ctcattggtg cggcgctgat gcgcagcggc tggctgaaag ggcagttcag cttacgtcac
    92761 tatcgtcgta ctggttttgt gctggtggcg attggggtga ccattaacct tcctgccatc
    92821 gccctgcaat ggcagctgga ctgggcgtat cgctggtgtg ccttcttact tcaaatgccg
    92881 cgggaactga gtgcgccgtt tcaggcgatt ggctatgcgt cgctgtttta tggcttctgg
    92941 ccgcaattaa gccgctttaa gctggtgctg gcaatcgcct gcgtcggacg gatggcgctg
    93001 accaactatc tattgcaaac gctgatttgt accacgcttt tttaccacct cggtttgttt
    93061 atgcattttg atcgcctgga gctgctggcg tttgttattc cggtatggct ggcgaatatc
    93121 ctcttctctg ttatctggct gcgttacttc cgccaggggc cggtggaatg gctctggcgt
    93181 cagttaactt tgcgtgctgc cggaacggca atatctaaaa catcaagata acgatctgga
    93241 tcacattcgt taacaaaacg gctgtaaccg tttccattgc tgtgactcga ttcacgaagt
    93301 cctgtattca gtgctgacaa aatagccgcc agcaagcagt catttactgc aatctcataa
    93361 caggtagtga atatgatcac cattcgtgat gtagcgcgtc aggctggcgt ctctgtggca
    93421 acggtttccc gggtgctcaa taacagcacg ctggtcagtg ccgacacgcg tgaagcagta
    93481 atgaaagccg tgagtgagct ggattatcgg ccaaatgcca atgcccaggc gctggcaact
    93541 caggttagcg ataccattgg cgtggtggtg atggacgttt ctgatgcttt tttcggcgcg
    93601 ctggtaaaag cggtggatct ggtcgcccag cagcatcaga aatacgtgct aatcggcaat
    93661 agctatcatg aagcggaaaa agagcgtcac gccattgagg tgttaattcg ccagcgttgt
    93721 aatgcgttga ttgttcactc aaaagcattg agtgacgatg aactggcgca atttatggat
    93781 aacattcccg gtatggtgtt aatcaaccgc gttgtgccgg ggtacgccca tcgttgcgtt
    93841 tgcctggata atctcagcgg tgcccgaatg gcgacgcgca tgttgctgaa taactgtcat
    93901 caacgtattg gttatctttc ttccagccac ggcattgaag atgacgccat gcgtaaagca
    93961 ggctggatga gtgcgttgaa agagcaggat attattccgc cggaaagctg gattggcact
    94021 ggtacgccgg acatgccggg cggtgaggcg gcgatggttg aactgctggg gcgcaatcta
    94081 caacttaccg ctgtatttgc ttataacgac aatatggccg ctggcgcact gacagcatta
    94141 aaagataatg gcattgcgat tccgttacat ctctcaatca tcggtttcga tgatattccc
    94201 atcgcccgtt acaccgaccc gcaattaacg accgtgcgtt atcccattgc ttcaatggcg
    94261 aaattagcca ccgaactggc cttgcagggg gcagcaggca atattgatcc tcgtgccagc
    94321 cactgtttta tgccgacgtt agtgcgtcgc cattctgtcg caacacgcca gaatgcggcg
    94381 acgatcacta actcaacaaa tcaggcgatg taaccgcttt caatctgtga gtgatttcac
    94441 agtatcttaa caatgtgata gctatgattg caccgtttta acgttgtaac ccgtatgtaa
    94501 cagtgaataa tcactttcac cgaggtaata gcgtcataac aacaattaaa gccgttttct
    94561 ggagcgttac cgggcatgga agaacgaatt ttaaaaagtg agcttcggcg ttcagtaaca
    94621 cttcattaac tctactgccc cgccgagcat ttatctcaag cactaccctg cataagaaaa
    94681 accggagata ccatgaataa gaaggtgtta accctgtctg ctgtgatggc cagcatgtta
    94741 ttcggtgccg ctgcacacgc tgctgatact cgcattggtg taacaatcta taagtacgac
    94801 gataacttta tgtctgtagt gcgcaaggct attgagcaag atgcgaaagc cgcgccagat
    94861 gttcagctgc tgatgaatga ttctcagaat gaccagtcca agcagaacga tcagatcgac
    94921 gtattgctgg cgaaaggggt gaaggcactg gcaatcaacc tggttgaccc ggcagctgcg
    94981 ggtacggtga ttgagaaagc gcgtgggcaa aacgtgccgg tggttttctt caacaaagaa
    95041 ccgtctcgta aggcgctgga tagctacgac aaagcctact acgttggcac tgattccaaa
    95101 gagtccggca ttattcaggg cgatttgatt gctaaacact gggcggcgaa tcagggttgg
    95161 gatctgaata aagatggtca gattcagttc gtactgctga aaggtgaacc gggccatccg
    95221 gatgcagaag cacgtaccac ttacgtgatt aaagaattga acgacaaagg catcaaaact
    95281 gaacagttac agttagatac cgctatgtgg gacaccgctc aggcgaaaga taagatggac
    95341 gcctggctgt ctggcccgaa cgccaacaaa atcgaagtgg ttattgctaa caacgatgcg
    95401 atggcaatgg gtgcggttga agcgctgaaa gcacacaaca agtccagcat tccggtgttt
    95461 ggcgtcgatg cgctgccaga agctctggcg ctggtgaaat ccggtgcact ggcgggcacc
    95521 gtactgaacg atgctaacaa ccaggcgaaa gcgacctttg atctggcgaa aaatctggcc
    95581 gatggcaaag gtgcggctga tggcaccaac tggaaaatcg aaaacaaagt ggtccgcgta
    95641 ccttatgttg gcgtagataa agacaacctg gctgaattca gcaagaaata agactgattg
    95701 ggcgcagtct attactgcgc ccttattgta tggccaacaa ggtaaaatta tatggtcagc
    95761 tcaacgactc cgtcttccgg ggaatacttg ttggaaatga gcggtatcaa caagtctttt
    95821 cctggtgtta aggcacttga taacgttaat ttaaaagtcc ggccacattc tatccatgca
    95881 ttaatggggg aaaacggcgc aggaaaatca acattattaa aatgcctgtt tggtatttat
    95941 caaaaagact ccggcaccat tttattccag ggtaaagaga tcgatttcca ttctgccaaa
    96001 gaagcactgg aaaatggtat ttcgatggta caccaggagt taaacctggt attacaacgt
    96061 tcggtgatgg ataacatgtg gctggggcga tatcccacca aaggcatgtt tgtcgatcag
    96121 gacaaaatgt accgcgaaac caaagcgatt tttgatgaac tggatattga tatcgatccg
    96181 cgtgcgcgcg tcggcacatt atccgtttcg caaatgcaga tgatcgaaat cgccaaagcg
    96241 ttttcctata acgcgaaaat tgtgattatg gatgaaccga cttcttcgtt aaccgaaaaa
    96301 gaggtcaatc atctgttcac tattattcgt aaattaaaag agcgcggctg cggtattgtt
    96361 tatatctcgc ataaaatgga agaaatcttc cagttatgtg atgaagttac cgtattgcgc
    96421 gacggtcagt ggatcgccac cgaaccgctg gcaggactga cgatggacaa gatcatcgcc
    96481 atgatggttg ggcgttctct taaccagcgt ttccctgaca aagaaaacaa gccgggcgaa
    96541 gtcatcctcg aggtgcgtaa cctgacgtca ctgcgccagc cgtcgattcg cgatgtctcg
    96601 tttgatctgc ataaagggga gatcctcggt attgccggtc tggtgggggc gaaacgtacc
    96661 gatattgttg agacgttatt tggtattcgc gagaaatcgg ctggcaccat tacgttgcac
    96721 ggcaaacaga tcaataacca taatgccaac gaagccataa atcacggatt tgcactggta
    96781 actgaggagc gccgctcaac gggaatttat gcctatctgg atattagttt taactcgtta
    96841 atttccaata ttcgcaacta caaaaataaa gttggtttac tggataactc gcggatgaaa
    96901 agcgataccc agtgggtgat tgattcgatg cgggtaaaaa cgccgggtca tcggacgcaa
    96961 attggttcgc tctccggtgg taatcagcaa aaggtgatta ttggtcgctg gctactaacg
    97021 caaccagaaa tattaatgct cgatgaaccg acgcgcggta ttgatgtcgg ggcgaagttt
    97081 gaaatttatc agttaattgc cgaactggcg aagaaaggca aggggattat tattatctcc
    97141 tctgaaatgc ctgagttgtt agggataaca gaccgtattc tggtcatgag caatggtctc
    97201 gtttccggaa ttgtcgatac aaaaacaaca acgcaaaacg aaattctgcg tcttgcgtct
    97261 ttgcaccttt aagattaggg gcttcccatg agtgcgttaa ataagaaaag ttttcttact
    97321 tacctgaaag agggcggtat ttacgtcgtt cttttagttt tgctggcgat tattattttc
    97381 caggacccaa catttttaag tctgttgaac ttaagtaata ttctcaccca gtcatcggtg
    97441 cgtattatta tcgcgctcgg tgtggcaggg ttaattgtca cccaggggac cgatctttct
    97501 gctggtcgtc aggtagggct ggcggcagtg gtggctgcga cattattgca gtccatggat
    97561 aacgccaaca aagtgttccc ggaaatggcg acgatgccga ttgcgctggt tattctgatt
    97621 gtctgtgcca ttggtgcggt gatcggtttg atcaacggtc tgattatcgc ttatctcaac
    97681 gtgacgccgt tcattaccac gctcggcacg atgatcatcg tctatggaat caactcgctc
    97741 tattacgact ttgtcggggc gtcgccaatt tctggttttg acagtggctt ctctaccttt
    97801 gctcagggct ttgtcgcgct ggggagtttc cgtctctctt acatcacctt ctacgcgttg
    97861 attgcggtgg cgttcgtctg ggtgttgtgg aacaaaaccc gcttcggtaa gaacattttt
    97921 gccattggcg gtaacccgga agcggcaaaa gtatctggtg tcaacgtcgg cctgaacctg
    97981 ctgatgatct acgcgttgtc tggcgtgttc tatgcctttg gcgggatgtt agaagccgga
    98041 cgtatcggct ctgccaccaa caacctcggc tttatgtatg agctggatgc tatcgcggcg
    98101 tgcgtggtag gcggtgtatc gttcagcggc ggtgtgggga cggtgattgg cgtggtgacc
    98161 ggggtaatta tttttaccgt catcaactat ggcctgacgt atatcggcgt aaacccatac
    98221 tggcagtaca tcatcaaagg ggcgattatt atcttcgccg tagcgctgga ttcactgaaa
    98281 tacgcgcgta agaagtgatg tgattgtgga tattgccgga tgcgctgcat ccggcaatcg
    98341 gtgccaaatg ccggatgcgt ctctggtttt acaacgttac cgggtgttct ttctcgcctt
    98401 tcttaaactt cacttccccg agctcaatac aacccaccgg gcagacgtga ccacaaagca
    98461 gacaacccac acatttctcg gtattacaat gcggtgtgcg ggttttctcg ctccattcca
    98521 tcgcctggtg accgccgtcg taacaggaaa tataacagcg tccacagcca acacatttat
    98581 caagattgat acggggatag acaatataac tgcggtctaa atcttccgcc gggacaatat
    98641 tgttattcgc cagacctacc atctcctgca gcgaatcaaa tccctgatcg gcgagataat
    98701 gcgacaaccc gcttgccata tcttccacta tccgataccc gtactgcatg atgccggtgg
    98761 tcacctgtaa cgttgctgcg ccgagcaata aaaactcagc cgcatcctcc caggtttcaa
    98821 tgccgccgat accgctgatt gggaaatcgc acagttctgg atgggtgcgc atctgctgaa
    98881 tgaagcgcag ggcgatcggt tttaccgctt taccggaata tccggaaata ctcgattttc
    98941 cgttaacgat cggcataccg attttctgat taagatcgat attggtgatg gatttaacgg
    99001 tgttaatcgc cgcaatgcca tctgcgccgc cgcgcttcgc cgccagcgcc acttcgcaca
    99061 tatcaccgat attcggcgtc atcttcgcca gcattggcag cgtggaaccc cgtttcactg
    99121 cccgacaata tttttctacc agctccgggc tttgcccgac atcgctaccc atcgcatgag
    99181 aagtcatttg cggacaggag aagttacact cgatcatatc cgcgccagct tcttgcacca
    99241 ggcgcgccag ctcctcccat tgctgctcat tttcccccat gatcgaagcg atcaatactt
    99301 tgtccgggta atcttccttc agctgacgca gggcggccag attctcttcc aacggatgtt
    99361 cagcaatctg ctccatattt ttgaagccga taaaaccggt atcttctttc accagatgat
    99421 caaaacgcgg cgagacttcg ttggcgataa aaaagccgat cgttttaaac accacgccgc
    99481 cccaacctgt gtcgtaggct ttggcacaca tctcatagca gttgcctaca ggcgaagaag
    99541 agaggcagaa cgggttggga aacttcacgc cgcaaaaagt aatcgaaaga tctttcgtta
    99601 acatgagcaa gctccctcta aatagtgatg aatcgcctcg gcggcttctt tcccggtttt
    99661 cacggcatag accacggttt tgtcaccctc aacaatatcg ccagcagcaa agacttgcgg
    99721 atcgcgggtc tgataatttt gtgttttgat ggtgttacgc tgcggctcta actccgcaaa
    99781 ggcatccagt ctggcatgct gaccgacggc gagaataatt ttatctgccg ccatcgtcag
    99841 ttcgcccggt aaccgtacat gcttaaacgt gactttattg ccttccacgg ctactggcgt
    99901 gaatccatcg atgatcgaaa cgcccagctc ccgggcgctg gcaaactctt tttcgcttgc
    99961 cggaaactca tctaactctt cacgcgctac gcaggttacc gcctgacagc cgagaacttt
   100021 cagcgtgctg gctacgtcca tcgcgacatc accgccgccg ataattaatg cgctttgtgg
   100081 aatgctgata tcgccttgcg cctgtcgtac acgttgcagg aagtcgacgg caatctcaac
   100141 gtcactatgc tcaaacagcg gtagcccgga accgcttgat aaccccacgg tgaccagtac
   100201 cgcgcggttt tctgctttca gctgctcaag ggtgagtgtg ttaccgactt cgttgttgca
   100261 cttaatggtc acgcccattt tttcaatacg ggcgatctct gcatccagca ctgattgcgg
   100321 taaccggaat tgcggaatac cgttacgcaa ccagctaccg gggtgcgctt ctttctcata
   100381 aatcgtgacg tcataaccct ggtttgtcag tgttacactg gcctgcaatc cggcaggacc
   100441 tgcgccaata atcgcgactt tgccgagcgt tttagtaccg ggctgataaa tttccatccc
   100501 agtttgttgt tcaaaatcag taacaaaacg ctgtaagcga ccgatatcaa tgggagtatc
   100561 aacaccggca cgggtacaac cgctttgaca taatttctcc gtcgggcaca ctctggcaca
   100621 aacggcaccg agggcattat tttcgcgaat tgtctcggca gcgcctttaa aattacgaaa
   100681 gtagattgag cgaataaatt tccccggatc ggtctgtgcc gggcaagcct gactacaggg
   100741 agcgtcatga cataataaac agcgagaggc ttctttaatc gccagtaaag gcgtaaaagc
   100801 cggagtgagt tcatccagat aattttgttg cggcatgtga tcttccttaa tgctatgagt
   100861 aattaaggcg aacgctaaat atactcgtca tacttcaagt tgcatgtgct gcgtctgcgt
   100921 tcgctcaccc cagtcactta cttatgtaag ctcctgggga ctcactcact tgtcgccttc
   100981 ctgcaactcg aattatttag agtataaata ttgcgtgctg atattaaggc tatgcgcgtg
   101041 gggaaattta tactgtgaaa ggattcacaa atagctgcgg ttcagaatgt tatatccgca
   101101 gcttattgag tgaagtaata attattctca ataattaaca gaaaagagaa aatattaacg
   101161 atagaaaata agataaacaa tcatgccgat agataaaatt ccgaagccga tatatgccac
   101221 catataagcg aaaaagagtc cgggattttt tgctcgccag acatacaccg gttccggtgc
   101281 atttttaacc cgtttatcaa tcgcgcctgc gcgccagcct ttccatgctt cgcggaaaca
   101341 aaatatcgga ataaggaaaa aaacggcaac gacaaaaaac tgctgtacat ccataactac
   101401 tttccttgtt tcttttgtaa ttcaagtaac tgttcgggtg tgacggcggg atacccctgc
   101461 gcatcttccg gcacctggtg catagccgga atagggacca gcggccctaa aaaacgcggt
   101521 tcacgtttaa aaatataaag gtcagccagc gcaccgaaac gggcggcaaa ttcgcgaata
   101581 cgtactgaca gcatatcttt cggtgacggt acggcataac actgagcctg aatccccata
   101641 tgcagcgcaa taaataatgc ccgctcacag tggaaacgtt gggtgataat aatgaaatca
   101701 ttagtatcga aaactttgcg tgtacgcacg atggaatcca gcgtacgaaa gcctgcgtaa
   101761 tcgagaacaa tatctgatgg gtcgacacca gcagcgatta aatctttgcg catggtcatc
   101821 ggctcattat aactttgcaa tgcgttatcg ccgctcagta atagataatt taccttaccg
   101881 ctgttatagg cattaatcgc tccttgaatg cggtagcgat aatactgatt aattacgcca
   101941 gtacgataat attttgctgt tccgagcacc acaccgacct ggcggtaggg gagatcctgc
   102001 aattcgtcgt agatataagg cgcggttttc cagctcatcc agcgatcgag gccgagcaca
   102061 gtcaacagca gcaagccgat caggactaac aggctgagga acacgcgctt taacatgcag
   102121 gagactcgat ctaaggaaaa tttccatcag gctactttac ccgctggttt tgcgcaagaa
   102181 acggcaaact gtttgccggg aatttcgaca ccaggagagg gctggcaagc cggacaaggc
   102241 gttcacgccg catccggcac caggcttaag cgagaagcac tcggtcgata ctgtgacagc
   102301 cgagagcttt cagcgttgcg gaggtggcat cccactgaat caacggcgca tcggcgtttt
   102361 ctgccagaac cgcgcgctgg atatccgggt aatcataacc cttgagattc aatagaatta
   102421 acgctccctg caacggtggc agagtcgggt tgaatgcggc gttttcagcg tagctgccgc
   102481 tgaaaatacg accgtcttta cattccagcg cgacaccgct tggcgactta ctgtaaggca
   102541 tgtgcgaacg gtttgccgct gcaatcgccg cctgagaaag cgcatcacca gtcagcgcat
   102601 agccgtgatc ctgctcgtcc atcagcagcg ttttaatctc cagatctttc ggcccaaagg
   102661 catccggcag atagtcacgc agcgcgtgtg cctcgcggcc cggcagatga atacgcagat
   102721 ccagaccgct gttcagttca ttcataaact gacggcagtg accacaaggc gtgtagttaa
   102781 cggtgatggc tgcaagcgct ttttcaccac tcaaccaggc gtggctgatc gcgctttgtt
   102841 cggcatgaac ggtttgctgc attgtcgcac caataaattc catattggca ccgaaatacc
   102901 aggttccgct cacaccgcgc gcaattgcgc caacattaaa attcgacaat ggcgtacgcg
   102961 cacaggccgc cgccagcgga agtagtgcga atgccagcgc gtcttcgtcc agccccgttg
   103021 cgctcttcag cgatgagact tgctccccgg tcaacaaagc ggggaagtac ttgtctgcca
   103081 gaataggttc cagtgcagat tgcaagttat ccgcaagttg ggcaaaagcg gtttgaaaac
   103141 gtggatgcat ggcgttgcct cataatcatg taatgggata acagtttacg aacccgttaa
   103201 ggctttatat gtgatctgaa tctcattaat tatgcaacgc gtgaaactta catcaaaaat
   103261 gcgcgacgca tcgcaaattt tagcccatta ctgccagaat aatcgggaaa aggaacggtg
   103321 cgatcagcga agtaattatc ccgcataaca ccagcgctag cgaactaaat gcaccttcct
   103381 gataatccag ctcggcgcag cgcgccgtac cgagggcgtg cgaggcagtc cccattgcca
   103441 gaccgcgcgc agctttggta cgaatacgca tcgcattaag caatgtatgg ccaaataccg
   103501 cgccgaggat gccgacgaaa atcacgcaaa ctgcgctgat tgccggaata ccgccaatac
   103561 tgccgccaac cgccattgca ataggcgtgg tgactgattt cggcaggatt gacgcggcga
   103621 tttccggtga agcgcccatc aacaatgcca cggaagtccc cgtcaccatc gcaaccacgc
   103681 tgccgataaa acagatggtg atgatcgatt tccagcgcgc gcggatctgg tgtagctgct
   103741 catataaagg ataggccagc gcgacgaccg ccggttgcag cagatcgttt agcacttcgc
   103801 tacctttaaa gtagctgtcg taagagatgc cggtcagcat taaaaaagga atgatcacca
   103861 ccattgctac cagcaacggg ttaagcaggg gaaacttata ccgtgccgcc agtttgcggg
   103921 cggcaaaaaa gacaatcaac gtcagcggta atgaccacca gatattcgcc atcattcttc
   103981 tgatcctttc tgacctacga ctttacgttc accgtgtacc agttgtgaac tccagctcac
   104041 caccagaaaa accaccagcg tactgacagc acaggaaacc actaccgggc caaactgcgc
   104101 gcggagcaaa tcaaaatatt gcatgacgcc tacgccaatc ggcacaaaca atagcgccat
   104161 atagcgaatc agtacgtagc accccggatt gacccatttc gccggaagaa tttgcaaggc
   104221 cagcaggaca aacaggatca gcatcccgat gatgctgccc ggaatggtta ccggtagcag
   104281 ggaagcaatg aaaatgcctg catacaggca ggcataaatc aggacgaaag cgcgtaaata
   104341 ttgccagata atgttcagtg tcttactcat aatcaacacc ccagatgaga tggattcatc
   104401 atacaattaa ttcgtaaaac gtgctaccga tcacattaag aaatcagcgc ttattttttc
   104461 gctccccggc attacgcaat gcgcaacgaa ctcaggcata catcaagcat agagagggat
   104521 tgcagtttgc agcaatccct ctttgtagac ctttaatccg ctgaccatag gcgctaacat
   104581 agcgcctcat tattttgcgg gtgatgatat gcgtgtgtta ctggcaccga tggagggagt
   104641 gcttgactct ctggtgcgtg aattgctgac cgaagttaac gactacgatc tgtgcatcac
   104701 cgagtttgtc cgcgtggtgg atcaactgct gccggtaaaa gtttttcatc gcatttgccc
   104761 tgagctacaa aacgccagcc ggacaccatc cggtacgctg gtgcgcgtgc agttgttggg
   104821 tcagttccca caatggctgg cagagaacgc cgcccgtgcg gtggaattag gttcctgggg
   104881 cgtggatctc aattgcggct gcccgtcgaa aacggtcaac ggtagcggtg gtggggcgac
   104941 gttactcaaa gatcctgaac tcatctacca gggtgcaaaa gcgatgcgtg aagctgtacc
   105001 ggcgcatttg cccgtcagcg tgaaagtgcg tctgggctgg gacagcggtg agaagaaatt
   105061 tgaaatcgcc gatgcggttc aacaggctgg tgctacggag ctggtggtgc atggacggac
   105121 aaaagagcag ggttaccgcg cggagcatat tgactggcag gcgattggcg agattcgcca
   105181 gcggctgaat attccggtga ttgccaacgg cgaaatctgg gactggcaga gcgcgcaaca
   105241 atgcattgcg atcagcggct gcgacgcagt gatgattggt cgcggggcgc tcaatattcc
   105301 caacctgagc cgggtagtaa aatataacga accgcgaatg ccgtggccgg aggtggttgc
   105361 tttgctgcaa aaatataccc gtctggaaaa gcagggcgat accgggttat atcacgttgc
   105421 gcggattaaa cagtggttga gttatttgcg taaagaatac gatgaagcaa cgggattatt
   105481 tcagcatgtt cgggtgttga ataattcccc tgatattgca agggctattc aggcaattga
   105541 tatcgagaaa ctctaaaaaa ccatagtgat gttttttgac aatgtgttag ctctttatca
   105601 ataggccgca cggttgtttg gtggcgtcaa aat
//
LOCUS       DAPOAV010000005        85007 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.005, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000005 DAPOAV010000000
VERSION     DAPOAV010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 85007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 85007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..85007
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.005"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            101..727
                     /locus_tag="RN951_000443"
     CDS             101..727
                     /locus_tag="RN951_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like protein"
                     /protein_id="HDX2525505.1"
                     /translation="MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQE
                     DIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFG
                     DNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCS
                     ACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV"
     gene            748..2850
                     /locus_tag="RN951_000444"
     CDS             748..2850
                     /locus_tag="RN951_000444"
                     /EC_number="1.2.7.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde ferredoxin oxidoreductase"
                     /protein_id="HDX2525506.1"
                     /translation="MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDE
                     VPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQ
                     MKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCV
                     AAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKR
                     LNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGDIPP
                     GNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGN
                     TCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYS
                     KGVFKRVLPAEEYAEIRWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWN
                     LGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPL
                     KLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTV
                     SPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRN
                     EHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQR
                     LGLEDIAADLAAHNLLPA"
     gene            2863..3501
                     /locus_tag="RN951_000445"
     CDS             2863..3501
                     /locus_tag="RN951_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707570.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhW family putative oxidoreductase system
                     protein"
                     /protein_id="HDX2525507.1"
                     /translation="MNHQDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAE
                     FIRQHSAAGQLVARAVFLSPPYLVAEEELSVLLESIKQNGDYADIACLTGSKDDYYYS
                     TQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEA
                     AIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP"
     gene            3565..4233
                     /locus_tag="RN951_000446"
     CDS             3565..4233
                     /locus_tag="RN951_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416186.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDX2525508.1"
                     /translation="MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDES
                     RCNGCNICARACRKTNHVPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCID
                     VCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLA
                     KGFPPICVSACPEHALIFGREDSPEIQAWLQQNKYYQYQLPGAGKPHLYRRFGQHLIK
                     KENV"
     gene            4230..5015
                     /locus_tag="RN951_000447"
     CDS             4230..5015
                     /locus_tag="RN951_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate reductase cytochrome B subunit"
                     /protein_id="HDX2525509.1"
                     /translation="MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVL
                     GLHALLRARGVKKSATDHGEKIYLYSKAVRLWHWSNALLFVLLLASGLINHFAMVGAT
                     AVKSLVAVHEVCGFLLLACWLGFVLINAVGDNGHHYRIRRQGWLERAAKQTRFYLFGI
                     MQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYW
                     LLQTHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH"
     gene            5019..5831
                     /locus_tag="RN951_000448"
     CDS             5019..5831
                     /locus_tag="RN951_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2525510.1"
                     /translation="MIITQADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYT
                     DWAESLVEYAWKKWLADENFAHQEVSSMQKLATAPGERPFCSQFARSDDHARIGCCED
                     NARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRI
                     ANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTG
                     VVDSIILGPGGSAALAYHDGERVRFAVAIEGENNIRAGVRYRLNEQHQFVEC"
     gene            complement(5843..7447)
                     /locus_tag="RN951_000449"
     CDS             complement(5843..7447)
                     /locus_tag="RN951_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-NAD(P)-binding protein"
                     /protein_id="HDX2525511.1"
                     /translation="MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPY
                     SDEENSKMMLANIASIEIPPIYCTYLEWLQKQEDSHLQRYGVKKETLHDRQFLPRILL
                     GEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLAVI
                     ATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFI
                     EDDKQHVVFHRDNASEKLNITLLSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKG
                     EEGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEKNL
                     QEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPS
                     ESIRRLLALREAGIIHILALGEDYKMEINESRTVLKTEDNSYSFDVFIDARGQRPLKV
                     KDIPFPGLREQLQKTGDEIPDVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTA
                     CAEIGEAMARAVVKPASRARRRLSFD"
     gene            complement(7573..7878)
                     /locus_tag="RN951_000450"
     CDS             complement(7573..7878)
                     /locus_tag="RN951_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HDX2525512.1"
                     /translation="MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTES
                     EKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKLA"
     gene            complement(7986..8062)
                     /locus_tag="RN951_000451"
     tRNA            complement(7986..8062)
                     /locus_tag="RN951_000451"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8026..8028),aa:Val,seq:gac)
     gene            complement(8067..8143)
                     /locus_tag="RN951_000452"
     tRNA            complement(8067..8143)
                     /locus_tag="RN951_000452"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8107..8109),aa:Val,seq:gac)
     gene            8451..9707
                     /locus_tag="RN951_000453"
     CDS             8451..9707
                     /locus_tag="RN951_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIDA repeat-containing protein"
                     /protein_id="HDX2525513.1"
                     /translation="MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENT
                     VVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQFEGGAISLSTLATVNGRH
                     PEGEFSVDKGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGE
                     LLVYPGGEASNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGT
                     DGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRA
                     PVELTGSVALLDGASMIIGYGAELQQSTITVQQGGVLILDGSTVKGDSVTFIVGNINL
                     NGGKLWLITDAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITD
                     ASRQTLCNALKLQPDEDGIGATLQPA"
     gene            complement(9748..11121)
                     /gene="mdtK"
                     /locus_tag="RN951_000454"
     CDS             complement(9748..11121)
                     /gene="mdtK"
                     /locus_tag="RN951_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter MdtK"
                     /protein_id="HDX2525514.1"
                     /translation="MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDM
                     AAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLI
                     MLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPG
                     MVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSM
                     RDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQI
                     ALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTV
                     SLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITF
                     TAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAI
                     ILQRASR"
     gene            11336..11977
                     /gene="ribE"
                     /locus_tag="RN951_000455"
     CDS             11336..11977
                     /gene="ribE"
                     /locus_tag="RN951_000455"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HDX2525515.1"
                     /translation="MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAH
                     NGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGH
                     IMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVH
                     LIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA"
     gene            complement(12017..13165)
                     /gene="cfa"
                     /locus_tag="RN951_000456"
     CDS             complement(12017..13165)
                     /gene="cfa"
                     /locus_tag="RN951_000456"
                     /EC_number="2.1.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclopropane fatty acyl phospholipid synthase"
                     /protein_id="HDX2525516.1"
                     /translation="MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNP
                     DFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIAGAR
                     LFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMIC
                     EKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTIL
                     LQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLN
                     VDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPE
                     IADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR"
     gene            complement(13456..14667)
                     /locus_tag="RN951_000457"
     CDS             complement(13456..14667)
                     /locus_tag="RN951_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bcr/CflA family multidrug efflux MFS
                     transporter"
                     /protein_id="HDX2525517.1"
                     /translation="MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVS
                     ASLSLFLAGFAAAQLLWGPLSDRYGRKLVLLIGLTIFALGSLGMLWVENAATLLVLRF
                     VQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQ
                     AIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSAS
                     FFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLV
                     LFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAA
                     LQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNH
                     GNAEVAHSESH"
     gene            14780..15712
                     /locus_tag="RN951_000458"
     CDS             14780..15712
                     /locus_tag="RN951_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX2525518.1"
                     /translation="MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWL
                     AVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIV
                     RPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAF
                     RDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKR
                     VVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALELENPFPDSACCLTWQQND
                     MSPALTWLLEYLGDSETLNKEWLREPEETPATGD"
     gene            complement(15709..16734)
                     /gene="purR"
                     /locus_tag="RN951_000459"
     CDS             complement(15709..16734)
                     /gene="purR"
                     /locus_tag="RN951_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor PurR"
                     /protein_id="HDX2525519.1"
                     /translation="MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELH
                     YSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLE
                     KQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVID
                     NAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQ
                     GDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDN
                     VRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADG
                     PFRDYRR"
     gene            17033..17122
                     /gene="ynhF"
                     /locus_tag="RN951_000460"
     CDS             17033..17122
                     /gene="ynhF"
                     /locus_tag="RN951_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein YnhF"
                     /protein_id="HDX2525520.1"
                     /translation="MSTDLKFSLVTTIIVLGLIVAVGLTAALH"
     gene            17288..18457
                     /locus_tag="RN951_000461"
     CDS             17288..18457
                     /locus_tag="RN951_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2525521.1"
                     /translation="MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGM
                     LISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRIL
                     TSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRM
                     SFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMF
                     TLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLL
                     MVIMLAIPFLARNEFGAAISMVVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAF
                     NLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS"
     gene            complement(18692..19273)
                     /gene="sodB"
                     /locus_tag="RN951_000462"
     CDS             complement(18692..19273)
                     /gene="sodB"
                     /locus_tag="RN951_000462"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Fe]"
                     /protein_id="HDX2525522.1"
                     /translation="MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIK
                     GTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFG
                     SFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWE
                     HAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA"
     gene            complement(19401..20216)
                     /gene="mepH"
                     /locus_tag="RN951_000463"
     CDS             complement(19401..20216)
                     /gene="mepH"
                     /locus_tag="RN951_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-endopeptidase MepH"
                     /protein_id="HDX2525523.1"
                     /translation="MARINRISITLCALLFTTLPLTPMAHASKQARESSATTHITKKA
                     DKKKSTATTKKTQKTAKKAASKSTTKSKTASSVKKSSITASKNAKTRSKHAVNKTASA
                     SFTEKCTKRKGYKSHCVKVKNAASGTLADAHKAKVQKATKVAMNKLMQQIGKPYRWGG
                     SSPRTGFDCSGLVYYAYKDLVKIRIPRTANEMYHLRDAAPIERSELKNGDLVFFRTQG
                     RGTADHVGVYVGNGKFIQSPRTGQEIQITSLSEDYWQRHYVGARRVMTPKTLR"
     gene            20550..20897
                     /gene="grxD"
                     /locus_tag="RN951_000464"
     CDS             20550..20897
                     /gene="grxD"
                     /locus_tag="RN951_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monothiol glutaredoxin 4"
                     /protein_id="HDX2525524.1"
                     /translation="MSTTIEKIQRQIAENPILLYMKGSPKLPSCGFSAQAVQALAACG
                     ERFAYVDILQNPDIRAELPKYANWPTFPQLWVDGELVGGCDIVIEMYQRGELQQLIKE
                     TAAKYKSEEPDAE"
     gene            complement(20948..25564)
                     /locus_tag="RN951_000465"
     CDS             complement(20948..25564)
                     /locus_tag="RN951_000465"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDX2525525.1"
                     /translation="MADNPDPSSLLPDVFSPATRDWFLRAFKQPTAVQPQTWHVAARS
                     EHALVIAPTGSGKTLAAFLYALDRLFREGGEDTREAHKRKTSRILYISPIKALGTDVQ
                     RNLQIPLKGIADERRRRGETEVNLRVGIRTGDTPAQERSKLTRNPPDILITTPESLYL
                     MLTSRARETLRGVETVIIDEVHAVAGSKRGAHLALSLERLDALLHTSAQRIGLSATVR
                     SASDVAAFLGGDRPVTVVNPPAMRHPQIRIVVPVANMDDVSSVASGTGEDSHAGREGS
                     IWPYIETGILDEVLRHRSTIVFTNSRGLAEKLTARLNELYAARLQRSPSIAVDAAHFE
                     STSGATSNRVQSSDVFIARSHHGSVSKEQRAITEQALKSGELRCVVATSSLELGIDMG
                     AVDLVIQVATPLSVASGLQRIGRAGHQVGGVSKGLFFPRTRRDLVDSAVIVECMFAGR
                     LENLTPPHNPLDVLAQQTVAAAAMDALQVDEWYSRVRRAAPWKDLPRRVFDATLDMLS
                     GRYPSGDFSAFRPKLVWNRETGILTARPGAQLLAVTSGGTIPDRGMYSVLLPEGEEKA
                     GSRRVGELDEEMVYESRVNDIITLGATSWRIQQITRDQVIVTPAPGRSARLPFWRGEG
                     NGRPAELGEMIGDFLHLLADGAFFSGTIPPWLAEENTIANIQGLIEEQRNATGIVPGS
                     RHLVLERCRDEIGDWRIILHSPYGRRVHEPWAVAIAGRIHALWGADASVVASDDGIVA
                     RIPDTDGKLPDAAIFLFEPEKLLQIVREAVGSSALFAARFRECAARALLMPGRTPGHR
                     TPLWQQRLRASQLLEIAQGYPDFPVILETLRECLQDVYDLPALERLMRRLNGGEIQIS
                     DVTTTTPSPFATSLLFGYVAEFMYQSDAPLAERRASVLSLDSELLRNLLGQVDPGELL
                     DPQVIRQVEEELQRLAPGRRAKGEEGLFDLLRELGPMTVEDLAQRHTGSSEEVASYLE
                     NLLAVKRIFPAMISGQERLACMDDAARLRDALGVRLPESLPEIYLHRVSYPLRDLFLR
                     YLRAHALVTAEQLAHEFSLGIAIVEEQLQQLREQGLVMNLQQDIWVSDEVFRRLRLRS
                     LQAAREATRPVAATTYARLLLERQGVLPATDGSPALFASTSPGVYEGVDGVMRVIEQL
                     AGVGLPASLWESQILPARVRDYSSEMLDELLATGAVIWSGQKKLGEDDGLVALHLQEY
                     AAESFTPAEADQANRSALQQAIVAVLADGGAWFAQQISQRIRDKIGESVDLSALQEAL
                     WALVWQGVITSDIWAPLRALTRSSSNARTSTRRSHRARRGRPVYAQPVSPRVSYNTPN
                     LAGRWSLLQVEPLNDTERMLALAENMLDRYGIISRQAVIAENIPGGFPSMQTLCRSME
                     DSGRIMRGRFVEGLGGAQFAERLTIDRLRDLATQATQTRHYTPVALSANDPANVWGNL
                     LPWPAHPATLVPTRRAGALVVVSGGKLLLYLAQGGKKMLVWQEKEELLAPEVFHALTT
                     ALRREPRLRFTLTEVNDLPVRQTPMFTLLREAGFSSSPQGLDWG"
     gene            complement(25657..26304)
                     /gene="rnt"
                     /locus_tag="RN951_000466"
     CDS             complement(25657..26304)
                     /gene="rnt"
                     /locus_tag="RN951_000466"
                     /EC_number="3.1.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease T"
                     /protein_id="HDX2525526.1"
                     /translation="MSDNAQLTGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITL
                     KMDEQGWLMPDTTLHFHVEPFVGANLQPEALAFNGIDPNDPDRGAVSEYEALHEIFKV
                     VRKGIKASGCNRAIMVAHNANFDHSFMMAAAERASLKRNPFHPFATFDTAALAGLALG
                     QTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLGGWPLSAAEEV"
     gene            complement(26407..26814)
                     /gene="gloA"
                     /locus_tag="RN951_000467"
     CDS             complement(26407..26814)
                     /gene="gloA"
                     /locus_tag="RN951_000467"
                     /EC_number="4.4.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HDX2525527.1"
                     /translation="MRLLHTMLRVGDLQRSIDFYTKVLGMKLLRTSENPEYKYSLAFV
                     GYGPETEEAVIELTYNWGVDKYELGTAYGHIALSVDNAAEACEKIRQNGGNVTREAGP
                     VKGGTTVIAFVEDPDGYKIELIEEKDAGRGLGN"
     gene            complement(26895..27992)
                     /gene="nemA"
                     /locus_tag="RN951_000468"
     CDS             complement(26895..27992)
                     /gene="nemA"
                     /locus_tag="RN951_000468"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-ethylmaleimide reductase"
                     /protein_id="HDX2525528.1"
                     /translation="MSSEKLYSPLKVGAITAANRIFMAPLTRLRSIEPGDIPTPLMAE
                     YYRQRASAGLIISEATQISAQAKGYAGAPGIHSPEQIAAWKKITAGVHAENGHMAVQL
                     WHTGRISHASLQPGGQAPVAPSALSAGTRTSLRDENGQAIRVETSMPRALELEEIPGI
                     VNDFRQAIANAREAGFDLVELHSAHGYLLHQFLSPSSNHRTDQYGGSVENRARLVLEV
                     VDAGIEEWGADRIGIRVSPIGTFQNTDNGPNEEADALYLIEQLGKRGIAYLHMSEPDW
                     AGGEPYTDAFREKVRARFHGPIIGAGAYTVEKAETLIGKGLIDAVAFGRDWIANPDLV
                     ARLQRKAELNPQRAESFYGGGAEGYTDYPTL"
     gene            complement(28029..28628)
                     /gene="nemR"
                     /locus_tag="RN951_000469"
     CDS             complement(28029..28628)
                     /gene="nemR"
                     /locus_tag="RN951_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416166.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NemR"
                     /protein_id="HDX2525529.1"
                     /translation="MNKHTEHDTREHLLATGEQLCLQRGFTGMGLSELLKTAEVPKGS
                     FYHYFRSKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILAYYQQTLNQFCQHGT
                     ISGCLTVKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRENHCLTFCGEPLQQA
                     QVLYALWLGANLQAKISRSFEPLENALAHVKNIIATPAV"
     gene            28731..28970
                     /locus_tag="RN951_000470"
     CDS             28731..28970
                     /locus_tag="RN951_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1289 domain-containing protein"
                     /protein_id="HDX2525530.1"
                     /translation="MAEQLEFFPVQSPCRGICQSDERGFCRGCFRSRDERFNWNKMSD
                     GEKQEVLRLCRQRLMRKLRANKPASSDEPEQPSLF"
     gene            29019..29915
                     /locus_tag="RN951_000471"
     CDS             29019..29915
                     /locus_tag="RN951_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HDX2525531.1"
                     /translation="MVQRITIAPQGPEFSRFVMGYWRLMDWNMSARQLVSFIEEHLDL
                     GVTTVDHADIYGGYQCEAAFGEALKLAPHLRERMEIVSKCGIATTAREENVIGHYITD
                     RDHIIKSAEQSLINLATDHLDLLLIHRPDPLMDADEVADAFKHLHQSGKVRHFGVSNF
                     TPAQFALLQSRLPFTLATNQVEISPVHQPLLLDGTLDQLQQLRVRPMAWSCLGGGRLF
                     NDDYFQPLRDELAVVAEELNAGSIEQVVYAWVLRLPSQPLPIIGSGKIERVRAAVEAE
                     TLKMTRQQWFRIRKAALGYDVP"
     gene            29996..30517
                     /gene="sodC"
                     /locus_tag="RN951_000472"
     CDS             29996..30517
                     /gene="sodC"
                     /locus_tag="RN951_000472"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Cu-Zn] SodC2"
                     /protein_id="HDX2525532.1"
                     /translation="MKRFSLAILALVVATGAQAASEKVEMNLVTSQGVGQSIGSVTIT
                     ETDKGLEFSPDLKALPPGEHGFHIHAKGSCQPATKDGKASAAESAGGHLDPQNTGKHE
                     GPEGAGHLGDLPALVVNNDGKATDAVIAPRLKSLDEIKDKALMVHVGGDNMSDQPKPL
                     GGGGERYACGVIK"
     gene            complement(30518..32530)
                     /locus_tag="RN951_000473"
     CDS             complement(30518..32530)
                     /locus_tag="RN951_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDX2525533.1"
                     /translation="MNASSWSLRNLPWFRATLAQWRYALRNTIAMCLALTVAYYLNLD
                     EPYWAMTSAAVVSFPTVGGVISKSLGRIAGSLLGAIAALLLAGHTLNEPWFFLLSMSA
                     WLGFCTWACAHFTNNVAYAFQLAGYTAAIIAFPMVNITEASQLWDIAQARVCEVIVGI
                     LCGGMMMMILPNSSDATALLTALKNMHARLLEHASLLWQPETTDAIRAAHEGVIGQIL
                     TMNLLRIQAFWSHYRFRQQNARLNALLHQQLRMTSVISSLRRMLLNWPSPPGATREIL
                     EQLLTALASSQTDVYTVARIIAPLRPTNVADYRHVAFWQRLRYFCRLYLQSSQELHRL
                     QSGVDDHTRLPRTSGLARHTDNAEAMWSGLRTFCTLMMIGAWSIASQWDAGANALTLA
                     AISCVLYSAVAAPFKSLSLLMRTLVLLSLFSFVVKFGLMVQISDLWQFLLFLFPLLAT
                     MQLLKLQMPKFAALWGQLIVFMGSFIAVTNPPVYDFADFLNDNLAKIVGVALAWLAFA
                     ILRPGSDARKSRRHIRALRRDFVDQLSRHPTLSESEFESLTYHHVSQLSNSQDALARR
                     WLLRWGVVLLNCSHVVWQLRDWESRSDPLSRVRDNCISLLRGVMSERGVQQKSLAATL
                     EELQRICDSLARHHQPAARELAAIVWRLYCSLSQLEQAPPQGTLAS"
     gene            complement(32530..33387)
                     /locus_tag="RN951_000474"
     CDS             complement(32530..33387)
                     /locus_tag="RN951_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416161.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HDX2525534.1"
                     /translation="MSIKTIKYFSTIIVAVVAVLAGWWLWNYYMQSPWTRDGKIRAEQ
                     VSITPQVSGRIVELNIKDNQLVNAGDLLLTIDKTPFQIAELNAQAQLAKAQSDLAKAN
                     NEANRRRHLSQNFISAEELDTANLNVKAMQASVDAAQATLKQAQWQLAQTEIRAPVSG
                     WVTNLTTRIGDYADTGKPLFALVDSHSFYVIGYFEETKLRHIREGAPAQITLYSDNKT
                     LQGHVSSIGRAIYDQSVESDSSLIPDVKPNVPWVRLAQRVPVRFALDKVPGDVTLVSG
                     TTCSIAVGQ"
     gene            complement(33390..33626)
                     /locus_tag="RN951_000475"
     CDS             complement(33390..33626)
                     /locus_tag="RN951_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1656 domain-containing protein"
                     /protein_id="HDX2525535.1"
                     /translation="MKFMLNATGLPLQDLVFGASVYFPPFFKAFAFGFVIWLVVHRLL
                     RGWIYAGDIWHPLLMDLSLFAICVCLALAILIAW"
     gene            33827..34261
                     /gene="slyA"
                     /locus_tag="RN951_000476"
     CDS             33827..34261
                     /gene="slyA"
                     /locus_tag="RN951_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416159.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SlyA"
                     /protein_id="HDX2525536.1"
                     /translation="MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLP
                     PDQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQTCASDRRAKRIKLTEKAEPLISE
                     MEAVINKTRAEILHGISAEELEQLITLIAKLEHNIIELQAKG"
     gene            complement(34308..34775)
                     /gene="slyB"
                     /locus_tag="RN951_000477"
     CDS             complement(34308..34775)
                     /gene="slyB"
                     /locus_tag="RN951_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein SlyB"
                     /protein_id="HDX2525537.1"
                     /translation="MIKRVLVVSMVGLSLVGCVNNDTLSGDVYTASEAKQVQNVSYGT
                     IVNVRPVQIQGGDDSNVIGAIGGAVLGGFLGNTVGGGTGRSLATAAGAVAGGVAGQGV
                     QSAMNKTQGVELEIRKDDGNTIMVVQKQGNTRFSPGQRVVLASNGSQVTVSPR"
     gene            35049..36158
                     /gene="anmK"
                     /locus_tag="RN951_000478"
     CDS             35049..36158
                     /gene="anmK"
                     /locus_tag="RN951_000478"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HDX2525538.1"
                     /translation="MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSL
                     KQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVNALLKEQNLQARDIVAIGCHGQTVW
                     HEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPT
                     ERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGK
                     VILPLLQNMLSDPYFSQPAPKSTGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAV
                     TISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTDAVGISGDDMEALAF
                     AWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANP"
     gene            36256..36585
                     /gene="mliC"
                     /locus_tag="RN951_000479"
     CDS             36256..36585
                     /gene="mliC"
                     /locus_tag="RN951_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416156.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-type lysozyme inhibitor"
                     /protein_id="HDX2525539.1"
                     /translation="MTMKKLLIIILPVLLSGCSAFNQLVERMQTDTLEYQCDEKPLTV
                     KLNNPRQEVSFVYDNQLLHLKQGISASGARYTDGIYVFWSKGDEATVYKRDRIVLNNC
                     QLQNPQR"
     gene            36644..37300
                     /gene="pdxH"
                     /locus_tag="RN951_000480"
     CDS             36644..37300
                     /gene="pdxH"
                     /locus_tag="RN951_000480"
                     /EC_number="1.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase"
                     /protein_id="HDX2525540.1"
                     /translation="MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACE
                     AKLADPTAMVVATVDEHGQPYQRIVLLKHYDEKGMVFYTNLGSRKAHQIENNPRVSLL
                     FPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGAWVSKQSSRISARGILESKF
                     LELKQKFQQGEVPLPSFWGGFRVSLEQIEFWQGGEHRLHDRFLYQRENDAWKIDRLAP
                     "
     gene            37429..38703
                     /gene="tyrS"
                     /locus_tag="RN951_000481"
     CDS             37429..38703
                     /gene="tyrS"
                     /locus_tag="RN951_000481"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HDX2525541.1"
                     /translation="MASSNLIKQLQERGLVAQVTDEEALAERLAQGPIALYCGFDPTA
                     DSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVD
                     KIRKQVAPFLDFDCGENSAIAANNYDWFGNMNVLTFLRDIGKHFSVNQMINKEAVKQR
                     LNREDQGISFTEFSYNLLQGYDFACLNKQYGVVLQIGGSDQWGNITSGIDLTRRLHQN
                     QVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFT
                     FMSIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLQAAKRITECLFSGSLSA
                     LSEADFEQLAQDGVPMVEMEKGADLMQALVDSELQPSRGQARKTIASNAITINGEKQS
                     DPEYFFKEEDRLFGRFTLLRRGKKNYCLICWK"
     gene            38762..39625
                     /gene="pdxY"
                     /locus_tag="RN951_000482"
     CDS             38762..39625
                     /gene="pdxY"
                     /locus_tag="RN951_000482"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal kinase"
                     /protein_id="HDX2525542.1"
                     /translation="MMKNILAIQSHVVYGHAGNSAAEFPMRRLGANVWPLNTVQFSNH
                     TQYGKWTGCVMPPSHLTEIVQGIAAIDKLHTCDAVLSGYLGSAEQGEHILGIVRQVKA
                     ANPQAKYFCDPVMGHPEKGCIVAPGVAEFHVRHGLPASDIIAPNLVELEILCEHAVNN
                     VEEAVLAARELIAQGPQIVLVKHLARAGYSRDRFEMLLVTADEAWHISRPLVDFGMRQ
                     PVGVGDVTSGLLLVKLLQGATLQEALEHVTAAVYEIMVTTKAMQEYELQVVAAQDRIA
                     KPEHYFSATKL"
     gene            complement(39669..40274)
                     /gene="gstA"
                     /locus_tag="RN951_000483"
     CDS             complement(39669..40274)
                     /gene="gstA"
                     /locus_tag="RN951_000483"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase GstA"
                     /protein_id="HDX2525543.1"
                     /translation="MKLFYKPGACSLASHITLRESGKDFTLVSVDLMKKRLENGDDYF
                     AVNPKGQVPALLLDDGTLLTEGVAIMQYLADSVPDRQLLAPVNSISRYKTIEWLNYIA
                     TELHKGFTPLFRPDTPEEYKPTVRAQLEKKLQYVNEALKDEHWICGQRFTIADACLFT
                     VLRWAYAVKLNLEGLEHIAAFMQRMAERPEVQDALSAEGLK"
     gene            complement(40380..41882)
                     /gene="dtpA"
                     /locus_tag="RN951_000484"
     CDS             complement(40380..41882)
                     /gene="dtpA"
                     /locus_tag="RN951_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpA"
                     /protein_id="HDX2525544.1"
                     /translation="MSTANQKPTESVSLNAFKQPKAFYLIFSIELWERFGYYGLQGIM
                     AVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLGDKVLGTKRVIMLGAIVLAIGY
                     ALVAWSGHDAGIVYMGMAAIAVGNGLFKANPSSLLSTCYEKNDPRLDGAFTMYYMSVN
                     IGSFFSMIATPWLAAKYGWSVAFALSVVGLLITIVNFAFCQRWVKQYGSKPDFEPINY
                     RNLLLTIIGVVALIAIATWLLHNQEVARMALGVVAFGIVVIFGKEAFAMKGAARRKMI
                     VAFILMLEAIIFFVLYSQMPTSLNFFAIRNVEHSILGLAVEPEQYQALNPFWIIIGSP
                     ILAAIYNKMGDTLPMPTKFAIGMVMCSGAFLILPLGAKFASDAGIVSVSWLVASYGLQ
                     SIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAGANLIGGYVAGMMAVPDNVTDP
                     LMSLEVYGRVFLQIGVATAVIAVLMLLTAPKLHRMTQDDAADKAAKAAVA"
     gene            complement(42493..43128)
                     /gene="nth"
                     /locus_tag="RN951_000485"
     CDS             complement(42493..43128)
                     /gene="nth"
                     /locus_tag="RN951_000485"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HDX2525545.1"
                     /translation="MNKAKRLEILTRLRENNPHPTTELNFSSPFELLIAVLLSAQATD
                     VSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIGLYNSKAENIIKTCRILLEQHNG
                     EVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTQFAPGKNVEQVE
                     EKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLCEYKEKVDI"
     gene            complement(43128..43823)
                     /gene="rsxE"
                     /locus_tag="RN951_000486"
     CDS             complement(43128..43823)
                     /gene="rsxE"
                     /locus_tag="RN951_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxE"
                     /protein_id="HDX2525546.1"
                     /translation="MSEIKDVIVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLA
                     TTLVLTLTNLTISTLRHWTPAEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFI
                     PLIVTNCIVVGRAEAFAAKKGPALSALDGFSIGMGATCAMFVLGSLREIIGNGTLFDG
                     ADALLGSWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAGKYLIDERMKKRRAEAA
                     AERALPNGETGNV"
     gene            complement(43827..44447)
                     /gene="rsxG"
                     /locus_tag="RN951_000487"
     CDS             complement(43827..44447)
                     /gene="rsxG"
                     /locus_tag="RN951_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxG"
                     /protein_id="HDX2525547.1"
                     /translation="MLKTIRKHGITLALFAAGSTGLTAAINQMTKTTIAEQASLQQKA
                     LFDQVLPAERYNNALAQSCYLVTAPELGKGEHRVYIAKQDDKPVAAVLEATAPDGYSG
                     AIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRLSDWITHFAGKKISGADDAHWAV
                     KKDGGDFDQFTGATITPRAVVNAVKRAGLYAQTLPAQLSQLPACGE"
     gene            complement(44451..45509)
                     /gene="rsxD"
                     /locus_tag="RN951_000488"
     CDS             complement(44451..45509)
                     /gene="rsxD"
                     /locus_tag="RN951_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxD"
                     /protein_id="HDX2525548.1"
                     /translation="MVFRIASSPYTHNQRQTSRIMLLVLLAAVPGIAAQLWFFGWGTL
                     VQILLASVSALLAEALVLKLRKQSVAATLKDNSALLTGLLLAVSIPPLAPWWMVVLGT
                     VFAVIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPHEIAVNIPGFIDAIQ
                     VIFSGHTASGGDMNTLRLGIDGISQATPLDTFKTSVRAGHSVEQIMQYPIYSGILAGA
                     GWQWVNLAWLAGGVWLLWQKAIRWHIPLSFLVTLALCAMLGWLFSPETLAAPQIHLLS
                     GATMLGAFFILTDPVTASTTNRGRLIFGALAGLLVWLIRSFGGYPDGVAFAVLLANIT
                     VPLIDYYTRPRVYGHRKG"
     gene            complement(45510..47732)
                     /gene="rsxC"
                     /locus_tag="RN951_000489"
     CDS             complement(45510..47732)
                     /gene="rsxC"
                     /locus_tag="RN951_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HDX2525549.1"
                     /translation="MLKLFSAFRKNKIWDFNGGIHPPEMKTQSNGTPLRQVPLAQRFV
                     IPLKQHIGAEGELCVSVGDKVLRGQPLTRGRGKMLPVHAPTSGTVTAIAPHSTAHPSA
                     LAELSVIIDADGEDCWIPRDGWADYRTRSREELIERIHQFGVAGLGGAGFPTGVKLQG
                     GGDKIETLIINAAECEPYITADDRLMQDCAAQVVEGIRILAHILQPREILIGIEDNKP
                     QAISMLRAVLADSNDISLRVIPTKYPSGGAKQLTYILTGKQVPHGGRSSDIGVLMQNV
                     GTAYAVKRAVIDGEPITERVVTLTGEAIARPGNVWARLGTPVRHLLNDAGFCPSADQM
                     VIMGGPLMGFTLPWLDVPVVKITNCLLAPSANELGEPQEEQSCIRCSACADACPADLL
                     PQQLFWFSKGQQHDKATTHNIADCIECGACAWVCPSNIPLVQYFRQEKAEIAAIRQEE
                     KRAAEAKARFEARQARLEREKAARLERHKSAAVQPAAKDKDAIAAALARVKEKQAQAT
                     QPIVIKAGERPDNSAIIAAREARKAQARAKQAELQQTNDAATVADPRKTAVEAAIARA
                     KARKLEQQQANAEPEQQVDPRKAAVEAAIARAKARKLEQQQANAEPEEQVDPRKAAVE
                     AAIARAKARKLEQQQANAEPEQQVDPRKAAVEAAIARAKARKREQQPANAEPEEQVDP
                     RKAAVEAAIARAKARKLEQQQANAVPEEQVDPRKAAVAAAIARAQAKKAAQQKVVNED
                     "
     gene            complement(47725..48303)
                     /gene="rsxB"
                     /locus_tag="RN951_000490"
     CDS             complement(47725..48303)
                     /gene="rsxB"
                     /locus_tag="RN951_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxB"
                     /protein_id="HDX2525550.1"
                     /translation="MNAIWIAVAAVSLLGLAFGAILGYASRRFAVEDDPVVEKIDEIL
                     PQSQCGQCGYPGCRPYAEAISCNGEKINRCAPGGEAVMLKIAELLNVEPQPLDGEAQE
                     ITPARMVAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTH
                     CISLQPVAETPDSWKWDLNTIPVRIIPVEHHA"
     gene            complement(48303..48884)
                     /gene="rsxA"
                     /locus_tag="RN951_000491"
     CDS             complement(48303..48884)
                     /gene="rsxA"
                     /locus_tag="RN951_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017456621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HDX2525551.1"
                     /translation="MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLA
                     TTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRL
                     LGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAV
                     ADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL"
     gene            complement(48961..49401)
                     /locus_tag="RN951_000492"
     CDS             complement(48961..49401)
                     /locus_tag="RN951_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416143.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2569 domain-containing protein"
                     /protein_id="HDX2525552.1"
                     /translation="MTTTTPQRIGGWLLGPLAWLLVALLSTTLALLLYTAALSSPQTF
                     QTLGGQALTTQILWGVSFITAIALWYYTLWLTIAFFKRRRCVPKHYIIWLLISVLLAV
                     KAFAFSPVEDGIAVRQLLFTLLATALIVPYFKRSSRVKATFVNP"
     gene            complement(49487..49702)
                     /gene="ydgT"
                     /locus_tag="RN951_000493"
     CDS             complement(49487..49702)
                     /gene="ydgT"
                     /locus_tag="RN951_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription modulator YdgT"
                     /protein_id="HDX2525553.1"
                     /translation="MTVQDYLLKFRKISSLESLEKLYDHLNYTLTDDQELINMYRAAD
                     HRRAELVSGGRLFDLGQVPKSVWHYVQ"
     gene            complement(49975..50100)
                     /gene="blr"
                     /locus_tag="RN951_000494"
     CDS             complement(49975..50100)
                     /gene="blr"
                     /locus_tag="RN951_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division septum protein Blr"
                     /protein_id="HDX2525554.1"
                     /translation="MNRLIELTGWIVLVVSVILLGVASHIDNYQPPEQSASVQHK"
     gene            50343..51383
                     /locus_tag="RN951_000495"
     CDS             50343..51383
                     /locus_tag="RN951_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310359.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDX2525555.1"
                     /translation="MSDNIRVGLIGYGYASKTFHAPLIAGTPGLELAVISSSDETKVK
                     ADWPTVTVVSEPKHLFNDPNIDLIVIPTPNDTHFPLAKAALEAGKHVVVDKPFTVTLS
                     QARELDALAKSLGRVLSVFHNRRWDSDFLTLKGLLAEGVLGEVAYFESHFDRFRPQVR
                     DRWREQGGPGSGIWYDLAPHLLDQAITLFGLPVSMTVDLAQLRPGAQSTDYFHAILSY
                     PQRRVILHGTMLAAAESARYIVHGSRGSYVKYGLDPQEERLKNGERLPQEDWGYDMRD
                     GVLTRVEGEERVEETLLTVPGNYPAYYAAIRDALNGDGENPVPASQAIQVMELIELGI
                     ESAKHRATLCLA"
     gene            complement(51417..52418)
                     /gene="add"
                     /locus_tag="RN951_000496"
     CDS             complement(51417..52418)
                     /gene="add"
                     /locus_tag="RN951_000496"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HDX2525556.1"
                     /translation="MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNISLPAQSLETLI
                     PHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARHGLHYVELRFSPG
                     YMAMAHQLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHR
                     DQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAER
                     IGHGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVAELAAHPLKTFLEHGIRASIN
                     TDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSAEEKRALREKVAAK"
     gene            complement(52522..53694)
                     /gene="malY"
                     /locus_tag="RN951_000497"
     CDS             complement(52522..53694)
                     /gene="malY"
                     /locus_tag="RN951_000497"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional maltose regulon transcriptional
                     repressor/cystathionine beta-lyase MalY"
                     /protein_id="HDX2525557.1"
                     /translation="MFDFSKVVDRHGTWCTQWDYVADRFGTADLLPFTISDMDFATAP
                     CIIEALNQRLMHGVFGYSRWKNDEFLAAIAHWFSTQHYTAIDSQTVVYGPSVIYMVSE
                     LIRQWSETGEGVVIHTPAYDAFYKAIEGNQRTVMPVALEKQADGWFCDMGKLEAVLAK
                     PECKIMLLCSPQNPTGKVWTCDELEIMADLCERHGVRVISDEIHMDMVWGEQPHIPWS
                     NVARGDWALLTSGSKSFNIPALTGAYGIIENSSSRDAYLSALKGRDGLSSPSVLALTA
                     HIAAYQQGAPWLDALRIYLKDNLTYIADKMNAAFPELNWQIPQSTYLAWLDLRPLNID
                     DNALQKALIEQEKVAIMPGYTYGEEGRGFVRLNAGCPRSKLEKGVAGLINAIRAVR"
     gene            complement(53704..55296)
                     /gene="malX"
                     /locus_tag="RN951_000498"
     CDS             complement(53704..55296)
                     /gene="malX"
                     /locus_tag="RN951_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS maltose transporter subunit IICB"
                     /protein_id="HDX2525558.1"
                     /translation="MTAKTAPKVTLWEFFQQLGKTFMLPVALLSFCGIMLGIGSSLSS
                     HDVITLIPVLGNPVLQAIFTWMSKIGSFAFSFLPVMFCIAIPLGLARENKGVAAFAGF
                     IGYAVMNLAVNFWLTNKGILPTTDAAVLKANNIQSILGIQSIDTGILGAVIAGIIVWM
                     LHERFHNIRLPDALAFFGGTRFVPIISSLVMGLVGLVIPLVWPIFAMGISGLGHMINS
                     AGDFGPMLFGTGERLLLPFGLHHILVALIRFTDAGGTQEVCGQTVSGALTIFQAQLSC
                     PTTHGFSESATRFLSQGKMPAFLGGLPGAALAMYHCARPENRHKIKGLLISGLIACVV
                     GGTTEPLEFLFLFVAPVLYVIHALLTGLGFTVMSVLGVTIGNTDGNIIDFVVFGILHG
                     LSTKWYMVPVVAAIWFVVYYVIFRFAITRFNLKTPGRDSEVASSIEKAVAGAPGKSGY
                     NVPAILEALGGADNIVSLDNCITRLRLSVKDMSLVNVQALKDNRAIGVVQLNQHNLQV
                     VIGPQVQSVKDEMAGLMHTVQA"
     gene            55471..56499
                     /gene="malI"
                     /locus_tag="RN951_000499"
     CDS             55471..56499
                     /gene="malI"
                     /locus_tag="RN951_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mal regulon transcriptional regulator MalI"
                     /protein_id="HDX2525559.1"
                     /translation="MATAKKITIHDVALAAGVSVSTVSLVLSGKGRISTATGERVNAA
                     IEELGFVRNRQASALRGGQSGVIGLIVRDLSAPFYAELTAGLTEALEAQGRMVFLLHG
                     GKDGEQLAQRFSLLLNQGVDGVVIAGAAGSSDDLRRMAEEKAIPVIFASRASYLDDVD
                     TVRPDNMQAAQLLTEHLIRNGHQRIAWLGGQSSSLTRAERVGGYCATLLKFGLPFHSD
                     WVLECTSSQKQAAEAITALLRHNPTISAVVCYNETIAMGAWFGLLKAGRQSGESGVDR
                     YFEQQVSLAAFTDATPTTLDDIPVTWASTPARELGITLADRMMQKITHEETHSRNLII
                     PARLIAAK"
     gene            56611..57378
                     /gene="hdhA"
                     /locus_tag="RN951_000500"
     CDS             56611..57378
                     /gene="hdhA"
                     /locus_tag="RN951_000500"
                     /EC_number="1.1.1.159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-alpha-hydroxysteroid dehydrogenase"
                     /protein_id="HDX2525560.1"
                     /translation="MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN
                     ADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAISKLGKVDILVNNAGGGGPK
                     PFDMPMADFRRAYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYA
                     SSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRL
                     GQPQDIANAALFLCSPAASWVSGQILTVSGGGVQELN"
     gene            57599..58189
                     /gene="uidR"
                     /locus_tag="RN951_000501"
     CDS             57599..58189
                     /gene="uidR"
                     /locus_tag="RN951_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator UidR"
                     /protein_id="HDX2525561.1"
                     /translation="MMDNMQTEAQPTRTRILNAAREIFSENGFHSASMKAICKSCAIS
                     PGTLYHHFISKEALIQAIILQDQERALARFREPIEGIHFVDYMVESIVSLTHEAFGQR
                     ALVVEIMAEGMRNPQVAAMLKNKHMTITEFVAQRMRDAQQKGEISPDINTAMTSRLLL
                     DLTYGVLADIEAEDLAREASFAQGLRAMIGGILTAS"
     gene            58580..60391
                     /gene="uidA"
                     /locus_tag="RN951_000502"
     CDS             58580..60391
                     /gene="uidA"
                     /locus_tag="RN951_000502"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HDX2525562.1"
                     /translation="MLRPVETPTREIKKLDGLWAFSLDRENCGIDQRWWESALQESRA
                     IAVPGSFNDQFADADIRNYAGNVWYQREVFIPKGWAGQRIVLRFDAVTHYGKVWVNNQ
                     EVMEHQGGYTPFEADVTPYVIAGKSVRITVCVNNELNWQTIPPGMVITDENGKKKQSY
                     FHDFFNYAGIHRSVMLYTTPNTWVDDITVVTHVAQDCNHASVDWQVVANGDVSVELRD
                     ADQQVVATGQGTSGTLQVVNPHLWQPGEGYLYELCVTAKSQTECDIYPLRVGIRSVAV
                     KGEQFLINHKPFYFTGFGRHEDADLRGKGFDNVLMVHDHALMDWIGANSYRTSHYPYA
                     EEMLDWADEHGIVVIDETAAVGFNLSLGIGFEAGNKPKELYSEEAVNGETQQAHLQAI
                     KELIARDKNHPSVVMWSIANEPDTRPQGAREYFAPLAEATRKLDPTRPITCVNVMFCD
                     AHTDTISDLFDVLCLNRYYGWYVQSGDLETAEKVLEKELLAWQEKLHQPIIITEYGVD
                     TLAGLHSMYTDMWSEEYQCAWLDMYHRVFDRVSAVVGEQVWNFADFATSQGILRVGGN
                     KKGIFTRDRKPKSAAFLLQKRWTGMNFGEKPQQGGKQ"
     gene            60388..61761
                     /gene="uidB"
                     /locus_tag="RN951_000503"
     CDS             60388..61761
                     /gene="uidB"
                     /locus_tag="RN951_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronide transporter"
                     /protein_id="HDX2525563.1"
                     /translation="MNQQLSWRTIVGYSLGDVANNFAFAMGALFLLSYYTDVAGVGAA
                     AAGTMLLLVRVFDAFADVFAGRVVDSVNTRWGKFRPFLLFGTAPLMIFSVLVFWVPTD
                     WSHGSKVVYAYLTYMGLGLCYSLVNIPYGSLATAMTQQPQSRARLGAARGIAASLTFV
                     CLAFLIGPSIKNSSPEEMVSVYHFWTIVLAIAGMVLYFICFKSTRENVVRIVAQPSLN
                     ISLQTLKRNRPLFMLCIGALCVLISTFAVSASSLFYVRYVLNDTGLFTVLVLVQNLVG
                     TVASAPLVPGMVARIGKKNTFLIGALLGTCGYLLFFWVSVWSLPVALVALAIASIGQG
                     VTMTVMWALEADTVEYGEYLTGVRIEGLTYSLFSFTRKCGQAIGGSIPAFILGLSGYI
                     ANQVQTPEVIMGIRTSIALVPCGFMLLAFVIIWFYPLTDKKFKEIVVEIDNRKKVQQQ
                     LISDITN"
     gene            61800..63065
                     /gene="uidC"
                     /locus_tag="RN951_000504"
     CDS             61800..63065
                     /gene="uidC"
                     /locus_tag="RN951_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416132.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronide uptake porin UidC"
                     /protein_id="HDX2525564.1"
                     /translation="MRKIVAMAVICLTAASGLTSAYAAQLADDEAGLRIRLKNELRRA
                     DKPSAGAGRDIYAWVQGGLLDFNSGYYSNIIGVEGGAYYVYKLGARADMSTRWYLDGD
                     KSFGFALGAVKIKPSENSLLKLGRFGTDYSYGSLPYRIPLMAGSSQRTLPTVSEGALG
                     YWALTPNIDLWGMWRSRVFLWTDSTTGIRDEGVYNSQTGKYDKHRARSFLAASWHDDT
                     SRYSLGASVQKDVSNQIQSILEKSIPLDPNYTLKGELLGFYAQLEGLSRNTSQPNETA
                     LVSGQLTWNAPWGSVFGSGGYLRHAMNGAVVDTDIGYPFSLSLDRNREGMQSWQLGVN
                     YRLTPQFTLTFAPIVTRGYESSKRDVRIEGTGILGGMNYRVSEGPLQGMNFFLAADKG
                     REKRDGSTLGDRLNYWDVKMSIQYDFMLK"
     gene            complement(63291..64799)
                     /locus_tag="RN951_000505"
     CDS             complement(63291..64799)
                     /locus_tag="RN951_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgA family protein"
                     /protein_id="HDX2525565.1"
                     /translation="MNKSLVAVGVIVALGVVWTGGAWYTGKKIETHLEDMVAQANAQL
                     KLTAPESNLEVSYQNYHRGVFSSQLQLLVKPIAGKENPWIKSGQSVIFNESVDHGPFP
                     LAQLKKLNLIPSMASIQTTLVNNEVSKPLFDMAKGETPFEINSRIGYSGDSSSDISLK
                     PLNYEQKDEKVAFSGGEFQLNADRDGKAISLSGEAQSGRIDAVNEYNQKVQLTFNNLK
                     TDGSSTLASFGERVGNQKLSLEKMTISVEGKELALLEGMEISGKSDLVNDGKTINSQL
                     DYSLNSLKVQNQDLGSGKLTLKVGQIDGEAWHQFSQQYNAQTQALLAQPEIANNPELY
                     QEKVTEAFFSALPLMLKGDPVITIAPLSWKNSQGESALNLSLFLKDPATTKEAPQTLA
                     QEVDRSVKSLDAKLTIPVDMATEFMTQVAKLEGYQEDQAKKLAKQQVEGASAMGQMFR
                     LTTLQDNTITTSLQYANGQITLNGQKMSLEDFVGMFAMPALNVPAVPAIPQQ"
     gene            complement(64900..66075)
                     /gene="manA"
                     /locus_tag="RN951_000506"
     CDS             complement(64900..66075)
                     /gene="manA"
                     /locus_tag="RN951_000506"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416130.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase"
                     /protein_id="HDX2525566.1"
                     /translation="MQKLINSVQNYAWGSKTALTELYGMENPSSQPMAELWMGAHPKS
                     SSRVQNAAGDIVSLRDVIESDKSTLLGEAVAKRFGELPFLFKVLCAAQPLSIQVHPNK
                     HNSEIGFAKENAAGIPMDAAERNYKDPNHKPELVFALTPFLAMNAFREFSEIVSLLQP
                     VAGAHPAIAHFLQQPDAERLSELFASLLNMQGEEKSRALAILKSALDSQQGEPWQTIR
                     LISEFYPEDSGLFSPLLLNVVKLNPGEAMFLFAETPHAYLQGVALEVMANSDNVLRAG
                     LTPKYIDIPELVANVKFEAKPANQLLTQPVKQGAELDFPIPVDDFAFSLHDLSDKETT
                     ISQQSAAILFCVEGDATLWKGSQQLQLKPGESAFIAANESPVTVKGHGRLARVYNKL"
     gene            66274..67920
                     /gene="fumB"
                     /locus_tag="RN951_000507"
     CDS             66274..67920
                     /gene="fumB"
                     /locus_tag="RN951_000507"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000066594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fumarate hydratase"
                     /protein_id="HDX2525567.1"
                     /translation="MSNKPFHYQAPFPLKKDDTEYYLLTSEHVSVSEFEGQEILKVAP
                     EALTLLARQAFHDASFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVL
                     PTCQDTGTAIIVGKKGQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNT
                     GTNLPAQIDLYAVDGDEYKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRT
                     LGTAACPPYHIAFVIGGTSAETNLKTVKLASAKYYDELPTEGNEHGQAFRDVELEKEL
                     LIEAQNLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIW
                     IEKLEHNPGKYIPEELRKAGEGEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVG
                     RDIAHAKLKERMDNGEGLPQYIKDHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQ
                     LQAQGGSMIMLAKGNRSQQVTDACKKHGGFYLGSIGGPAAVLAQGSIKSLECVEYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIQLTQCTRCVK"
     gene            68063..69466
                     /gene="fumC"
                     /locus_tag="RN951_000508"
     CDS             68063..69466
                     /gene="fumC"
                     /locus_tag="RN951_000508"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fumarate hydratase"
                     /protein_id="HDX2525568.1"
                     /translation="MNTVRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSL
                     IHALALTKRAAAKVNEDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQS
                     NMNMNEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQL
                     IPQLKTLTQTLNEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYS
                     LPHVAELALGGTAVGTGLNTHPEYARRVADELAVITCAPFVTAPNKFEALATCDALVQ
                     AHGALKGLAASLMKIANDVRWLASGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALT
                     MLCCQVMGNDVAINMGGASGNFELNVFRPMVIHNFLQSVRLLADGMESFNKHCAVGIE
                     PNRERINQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKAAALALGYLSEAEF
                     DSWVRPEQMVGSMKAGR"
     gene            complement(69463..70392)
                     /gene="tus"
                     /locus_tag="RN951_000509"
     CDS             complement(69463..70392)
                     /gene="tus"
                     /locus_tag="RN951_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication terminus site-binding protein"
                     /protein_id="HDX2525569.1"
                     /translation="MARYDLVDRLNTTFRQMEQELAIFAAHLEQHKLLVARVFSLPEV
                     KKEDEHNPLNRIEVKQHLGNDAQSLALRHFRHLFIQQQSENRSSKAAVRLPGVLCYQV
                     DNLSQAALVSHIQHINKLKTTFEHIVTVESELPTAARFEWVHRHLPGLITLNAYRTLT
                     VLHDPATLRFGWANKHIIKNLHRDEVLAQLEKSLKSPRSVAPWTREEWQRKLEREYQD
                     IAALPQNAKLKIKRPVKVQPIARVWYKGDQKQVQHACPTPLIALINRDNGAGVPDVGE
                     LLNYDADNVQHRYKPQAQPLRLIIPRLHLYVAD"
     gene            complement(70468..71769)
                     /gene="rstB"
                     /locus_tag="RN951_000510"
     CDS             complement(70468..71769)
                     /gene="rstB"
                     /locus_tag="RN951_000510"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RstB"
                     /protein_id="HDX2525570.1"
                     /translation="MKKLFIQFYLLLFVCFLVMSLLVGLVYKFTAERAGKQSLDDLMN
                     SSLYLMRSELREIPPHDWGKTLKEMDLNLSFDLRVEPLSKYHLDDISMHRLRGGEIVA
                     LDDQYTFLQRIPRSHYVLAVGPVPYLYYLHQMRLLDIALIAFIAISLAFPVFIWMRPH
                     WQDMLKLEAAAQRFGDGHLNERIHFDEGSSFERLGVAFNQMADNINALIASKKQLIDG
                     IAHELRTPLVRLRYRLEMSDNLSAAESQALNRDISQLEALIEELLTYARLDRPQNELH
                     LSEPDLPLWLSTHLADIQAVTPDKTVRIKTLVQGHYAALDMRLMERVLDNLLNNALRY
                     CHSTVETSLLLSGNRATLIVEDDGPGIAPENREHIFEPFVRLDPSRDRSTGGCGLGLA
                     IVHSIALAMGGTVNCDTSELGGARFSFSWPLWHNIPQFTSA"
     gene            complement(71773..72492)
                     /gene="rstA"
                     /locus_tag="RN951_000511"
     CDS             complement(71773..72492)
                     /gene="rstA"
                     /locus_tag="RN951_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416125.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RstA"
                     /protein_id="HDX2525571.1"
                     /translation="MNTIVFVEDDAEVGSLIAAYLAKHDMQVTVEPRGDQAEETILRE
                     NPDLVLLDIMLPGKDGMTICRDLRAKWSGPIVLLTSLDSDMNHILALEMGACDYILKT
                     TPPAVLLARLRLHLRQNEQATLTKGLQETSLTPYKALHFGTLTIDPINRVVTLANTEI
                     SLSTADFELLWELATHAGQIMDRDALLKNLRGVSYDGLDRSVDVAISRLRKKLLDNAA
                     EPYRIKTVRNKGYLFAPHAWE"
     gene            72621..72956
                     /locus_tag="RN951_000512"
     CDS             72621..72956
                     /locus_tag="RN951_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlpM family protein"
                     /protein_id="HDX2525572.1"
                     /translation="MGLVIKAALGALVVLLIGVLAKTKNYYIAGLIPLFPTFALIAHY
                     IVASERGIEALRATIIFSMWSIIPYFVYLVSLWYFTGMMRLPAAFVGSVACWGISAWV
                     LIICWIKLH"
     gene            complement(72953..73675)
                     /gene="folM"
                     /locus_tag="RN951_000513"
     CDS             complement(72953..73675)
                     /gene="folM"
                     /locus_tag="RN951_000513"
                     /EC_number="1.5.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydromonapterin reductase"
                     /protein_id="HDX2525573.1"
                     /translation="MGKTQPLPILITGGGRRIGLALAWHFINQKQPVIVSYRTHYPAI
                     DGLINAGAQCIQADFSTNDGVMAFADEVLKSTHGLRAILHNASAWMAEKPGAPLADVL
                     ACMMQIHVNTPYLLNHALERLLRGHGHAASDIIHFTDYVVERGSDKHIAYAASKAALD
                     NMTRSFARKLAPEVKVNSIAPSLILFNEHDDAEYRQQALNKSLMKTAPGEKEVIDLVD
                     YLLTSCFVTGRSFPLDGGRHLR"
     gene            complement(73712..75094)
                     /locus_tag="RN951_000514"
     CDS             complement(73712..75094)
                     /locus_tag="RN951_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDX2525574.1"
                     /translation="MEKKLGLSALTALVLSSMLGAGVFSLPQNMAAVASPAALLIGWG
                     ITGAGILLLAFAMLILTRIRPELDGGIFTYAREGFGELIGFCSAWGYWLCAVIANVSY
                     LVIVFSALSFFTDTPELRLFGDGNTWQSIVGASALLWIVHFLILRGVQTAASINLVAT
                     LAKLLPLGLFVVLAMMMFKLDTFKLDFTGLALGVPVWEQVKNTMLITLWVFIGVEGAV
                     VVSARARNKRDVGKATLLAVLSALGVYLLVTLLSLGVVARPELAEIRNPSMAGLMVEM
                     MGPWGEIIIAAGLIVSVCGAYLSWTIMAAEVPFLAATHKAFPRIFARQNAQAAPSASL
                     WLTNICVQICLVLIWLTGSDYNTLLTIASEMILVPYFLVGAFLLKIATRPLHKAVGVG
                     ACIYGLWLLYASGPMHLLLSVVLYAPGLLVFLYARKTHTHDNVLNRQEMVLIGMLLIA
                     SVPATWMLVG"
     gene            complement(75280..76224)
                     /locus_tag="RN951_000515"
     CDS             complement(75280..76224)
                     /locus_tag="RN951_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDX2525575.1"
                     /translation="MKLKNTLLASALLSATAFSVNAATELTPEQAAAVKPFDRVVVTG
                     RFNAIGEAVKAVSRRADKEGAASFYVVDTSDFGNSGNWRVVADLYKADAEKAEETSNR
                     VINGVVELPKDQAVLIEPFDTVTVQGFYRSQPEVNDAITKAAKAKGAYSFYIVRQIDA
                     NQGGNQRITAFIYKKDAKKRIVQSPDVIPADSEAGRAALAAGGEAAKKVEIPGVATTA
                     SPSSEVGRFFETQSSKGGRYTVTLPDGTKVEELNKATAAMMVPFDSIKFSGNYGNMTE
                     VSYQVAKRAAKKGAKYYHITRQWQERGNNLTVSADLYK"
     gene            76748..78280
                     /gene="pntA"
                     /locus_tag="RN951_000516"
     CDS             76748..78280
                     /gene="pntA"
                     /locus_tag="RN951_000516"
                     /EC_number="1.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit alpha"
                     /protein_id="HDX2525576.1"
                     /translation="MRIGIPRERLTNETRVAATPKTVEQLLKLGFTVAVESGAGQLAS
                     FDDKAFVQAGAEIVEGNSVWQSEIILKVNAPLDDEIALLNPGTTLVSFIWPAQNPELM
                     QKLAERNVTVMAMDSVPRISRAQSLDALSSMANIAGYRAIVEAAHEFGRFFTGQITAA
                     GKVPPAKVMVIGAGVAGLAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKE
                     EAGSGDGYAKVMSDAFIKAEMELFAAQAKEVDIIVTTALIPGKPAPKLITREMVDSMK
                     AGSVIVDLAAQNGGNCEYTVPGEIFTTENGVKVIGYTDLPGRLPTQSSQLYGTNLVNL
                     LKLLCKEKDGNITVDFDDVVIRGVTVIRAGEITWPAPPIQVSAQPQAAQKAAPEVKTE
                     EKCTCSPWRKYALMALAIILFGWMASVAPKEFLGHFTVFALACVVGYYVVWNVSHALH
                     TPLMSVTNAISGIIVVGALLQIGQGGWVSFLSFIAVLIASINIFGGFTVTQRMLKMFR
                     KN"
     gene            78291..79679
                     /gene="pntB"
                     /locus_tag="RN951_000517"
     CDS             78291..79679
                     /gene="pntB"
                     /locus_tag="RN951_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000014033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit beta"
                     /protein_id="HDX2525577.1"
                     /translation="MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIA
                     LIATIFGPDTGNVGWILLAMVIGGAIGIRLAKKVEMTEMPELVAILHSFVGLAAVLVG
                     FNSYLHHDAGMAPILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPLMLPNR
                     HKMNLAALVVSFLLLIVFVRTDSVGLQVLALLIMTAIALVFGWHLVASIGGADMPVVV
                     SMLNSYSGWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFG
                     TDGSSTGDDQEVGEHREITAEETAELLKNSHSVIITPGYGMAVAQAQYPVAEITEKLR
                     ARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGAND
                     TVNPAAQDDPKSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGD
                     AKASVDAILKAL"
     gene            complement(79704..80738)
                     /gene="tqsA"
                     /locus_tag="RN951_000518"
     CDS             complement(79704..80738)
                     /gene="tqsA"
                     /locus_tag="RN951_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2 transporter TqsA"
                     /protein_id="HDX2525578.1"
                     /translation="MAKPIITLNGLKIVIMLGMLVIILCGIRFAAEIIVPFILALFIA
                     VILNPLVQHMVRWRVPRVLAVSILMTIIVMAMVLLLAYLGSALNELTRTLPQYRNSIM
                     TPLQALEPLLQRVGIDVSVDQLAHYIDPNAAMTLLTNLLTQLSNAMSSIFLLLLTVLF
                     MLLEVPQLPGKFQQMMARPVEGMAAIQRAIDSVSHYLVLKTAISIITGLVAWAMLAAL
                     DVRFAFVWGLLAFALNYIPNIGSVLAAIPPIAQVLVFNGFYEALLVLAGYLLINLVFG
                     NILEPRIMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTIIVKIALEQTAGGQSI
                     AVLLSDLNKE"
     gene            81150..81515
                     /gene="mdtJ"
                     /locus_tag="RN951_000519"
     CDS             81150..81515
                     /gene="mdtJ"
                     /locus_tag="RN951_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtJ"
                     /protein_id="HDX2525579.1"
                     /translation="MYIYWILLGLAIATEITGTLSMKWASVSEGNGGFILMLVMISLS
                     YIFLSFAVKKIALGVAYALWEGIGILFITLFSVLLFDESLSLMKIAGLTTLVAGIVLI
                     KSGTRKARKPELEVNHGAV"
     gene            81502..81831
                     /gene="mdtI"
                     /locus_tag="RN951_000520"
     CDS             81502..81831
                     /gene="mdtI"
                     /locus_tag="RN951_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtI"
                     /protein_id="HDX2525580.1"
                     /translation="MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAA
                     VLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAG
                     MIMVKLA"
     gene            complement(81870..82691)
                     /locus_tag="RN951_000521"
     CDS             complement(81870..82691)
                     /locus_tag="RN951_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HDX2525581.1"
                     /translation="MRTTIAVVLGAISLTSAFVFADKPDVARSANDEVSTLFFGHDDR
                     VPVNDTTQSPWDAVGQLETASGNLCTATLIAPNLALTAGHCLLTPPKGKADKAVALRF
                     VSNKGLWRYEIHDIEGRVDPTLGKRLKADGDGWIVPPAAAPWDFGLIVLRNPPSGITP
                     LPLFEGDKAALTAALKAAGRKVTQAGYPEDHLDTLYSHQNCEVTGWAQTSVMSHQCDT
                     LPGDSGSPLMLHTDDGWQLIGVQSSAPAAKDRWRADNRAISVTGFRDKLDQLSQK"
     gene            complement(82791..82874)
                     /locus_tag="RN951_000522"
     CDS             complement(82791..82874)
                     /locus_tag="RN951_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2525582.1"
                     /translation="MVGRYRFEFILIILILCALIAARFYLS"
     gene            complement(82967..83302)
                     /locus_tag="RN951_000523"
     CDS             complement(82967..83302)
                     /locus_tag="RN951_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416114.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid shock protein"
                     /protein_id="HDX2525583.1"
                     /translation="MKKQIEGMTMKKVLALVVAAAMGLSSAAFAAETTTTPAPTATTT
                     KAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNTKAEQKAPEQKAQAAKKHAKKHSHQQP
                     AKPAAQPAA"
     gene            complement(83699..84952)
                     /locus_tag="RN951_000524"
     CDS             complement(83699..84952)
                     /locus_tag="RN951_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2525584.1"
                     /translation="MSRTTTVDGAPASDTDKQSISQPNQFIKRGTPQFMRVTLALFSA
                     GLATFALLYCVQPILPVLSQEFGLTPANSSISLSISTAMLAIGLLFTGPLSDAIGRKP
                     VMVTALLLASICTLLSTMMTSWHGILIMRALIGLSLSGVAAVGMTYLSEEIHPSFVAF
                     SMGLYISGNSIGGMSGRLISGVFTDFFNWRIALAAIGCFALASALMFWKILPESRHFR
                     PTSLRPKTLFINFRLHWRDRGLPLLFAEGFLLMGSFVTLFNYIGYRLMLSPWHVSQAV
                     VGLLSLAYLTGTWSSPKAGTMTTRYGRGPVMLFSTGVMLFGLLMTLFSSLWLIFAGML
                     LFSAGFFAAHSVASSWIGPRAKRAKGQASSLYLFSYYLGSSIAGTLGGVFWHNYGWNG
                     VGAFIALMLVIALLVGTRLHRRLHA"
BASE COUNT        21430 a        20917 c        22115 g        20545 t
ORIGIN      
        1 tatctggtgt tggggacaga gtcagcagcg tattagttga atgcttaata tcaggctgct
       61 gaattgtcag cactgtgttt gcgaagagga tgcgaaataa atgaacccgg ttgatcgtcc
      121 actattagat attggcttaa cgcgattaga attcttgcgt atatcaggaa aaggccttgc
      181 tggtctaaca attgcccctg cgttactgtc acttttgggt tgcaaacagg aagatattga
      241 tagcggcaca gtagggttga taaatacccc caaaggggtg ctggtgaccc agcgagcgcg
      301 atgcacgggt tgccaccgct gtgaaatctc ttgtaccaac ttcaacgatg gctcagtagg
      361 gacattcttc tcccgtatca aaatccatcg caattatttc tttggcgaca acggggttgg
      421 ctctggcggc ggcctgtatg gcgatctcaa ctataccgcg gacacctgcc gtcaatgcaa
      481 agagccgcaa tgcatgaacg tctgcccgat tggtgcgatt acctggcagc agaaagaagg
      541 ctgtattacc gtcgatcata aacgctgtat tggctgtagc gcctgtacta cggcatgccc
      601 gtggatgatg gccaccgtaa ataccgaaag taaaaaatcc tcgaaatgtg tgttatgcgg
      661 tgaatgcgca aacgcctgcc caacaggggc gttaaaaatt atcgagtgga aagatattac
      721 tgtgtgaatc ttgcaaagga aaaaatcatg gctaacggtt ggacaggtaa tatattaaga
      781 gtcaatctca cgacaggaaa tattaccctc gaagattcca gtaagtttaa aagttttgtc
      841 ggtggcatgg gcttcggcta caaaattatg tatgacgaag taccgccagg cacgaaacct
      901 ttcgatgaag cgaataaatt agtctttgct accggcccat taactggatc tggtgccccc
      961 tgtagttctc gcgtaaatat cacctcactt tctactttta ccaaaggaaa tttagtcgtc
     1021 gatgcccata tgggtggctt ttttgcagcg caaatgaaat tcgctggata cgacgtcatt
     1081 attatcgaag ggaaggcgaa atcaccggta tggctgaaga ttaaagatga caaagttagc
     1141 ctggaaaaag ccgatttctt atggggaaaa gggacgcgcg caacgacgga agaaatttgt
     1201 cgattgacca gtccggaaac ctgtgtggcg gctattggtc aggctgggga aaaccttgtt
     1261 cctctctctg gcatgttgaa tagccgtaac cacagcggcg gtgcgggaac tggcgcaata
     1321 atgggttcga aaaacctgaa agcgattgcg gttgaaggga cgaaaggggt caacattgcc
     1381 gatcgtcagg agatgaagcg tctcaatgat tacatgatga ctgaacttat tggtgcgaat
     1441 aacaaccatg tcgtgccaag tacgccacaa tcgtgggcag agtattcaga tcccaagtca
     1501 cgctggacag cacgtaaagg gctgttttgg ggcgcggctg aaggtggtcc gattgaaacg
     1561 ggtgacattc cgccaggcaa tcagaatacg gtcggctttc gtacctataa atccgttttt
     1621 gacttaggac cggcggcaga gaaatacaca gtaaaaatga gcggctgcca ctcttgcccg
     1681 atccgttgta tgacccaaat gaatattcct cgggtgaaag agtttggcgt gcccagcaca
     1741 ggtggtaaca cttgtgtagc aaactttgtc cataccacca tcttcccgaa cgggccgaaa
     1801 gattttgaag ataaagacga tggtcgtgtg attggtaacc tggtgggtct gaatttgttc
     1861 gatgactacg gcctatggtg taactacggg cagttgcatc gcgactttac ttattgttac
     1921 agcaaaggtg tgttcaagcg tgttctgcca gctgaagagt atgcagaaat tcgctgggat
     1981 caactggaag cgggtgacgt taacttcatt aaagattttt actaccgtct ggcgcatcgt
     2041 gtgggtgagc tgagtcacct ggctgatggt tcatatgcca tcgcagaacg ctggaatttg
     2101 ggtgaagagt actggggcta cgcgaaaaat aaactctggt cgccgtttgg ctatccggtt
     2161 caccatgcca atgaagcgtc agcgcaggtc ggttccattg ttaactgtat gttcaaccgt
     2221 gactgcatga cgcataccca tatcaacttt attggttccg gcttgccatt gaaactgcaa
     2281 cgtgaagtgg cgaaagaact ttttggttct gaagatgctt acgatgaaac caaaaactac
     2341 acgccaatca atgacgcaaa aattaaatat gcaaagtggt cgctgttgcg ggtctgtttg
     2401 cataacgccg tcaccctgtg caactgggtc tggccaatga ccgtttcgcc gctgaaaagc
     2461 cgtaattacc ggggcgatct ggcgcttgaa gccaaattct tcaaagcgat caccggcgaa
     2521 gagatgactc aggaaaaatt agatttagct gcagagcgta tttttacgtt gcatcgtgcc
     2581 tacacggtaa aactgatgca aaccaaagat atgcgtaatg aacacgatct tatctgttcc
     2641 tgggtattcg acaaggatcc gcagatcccg gtctttactg aaggtactga caaaatggat
     2701 cgtgacgata tgcatgcttc gctcacgatg ttctacaaag aaatgggctg ggacccacag
     2761 cttggttgtc caacccgcga aacattgcag cgtctggggc tggaagatat tgccgccgat
     2821 ctggcagcac acaatctact gcctgcgtaa ggaatgggta agatgaacca tcaggatgaa
     2881 ttgccgttag cgaaagtcag cgaagttgac gaggcgaagc ggcaatggtt gcaggggatg
     2941 cgtcaccccg ttgatacggt aaccgaacca gaacctgctg aaatcctggc tgagttcatt
     3001 cgccagcatt ctgcggctgg gcagctggtg gcgcgcgccg tgtttctctc gccaccctat
     3061 ttggttgcag aagaggaact gtcagttttg ctggaaagca ttaagcagaa cggagactac
     3121 gcggatatcg cttgtttgac gggaagcaag gatgattact attactcaac gcaggccatg
     3181 agtgaaaact acgcggcgat gtctttgcaa gttgtggagc aggacatttg tcgcgccatt
     3241 gcacacgccg ttcgttttga gtgccagacg tatcctcgtc cttacaaagt cgccatgctg
     3301 atgcaagcgc catattactt ccaggaagcg cagattgaag ccgcgatcgc cgcgatggat
     3361 gttgcacctg aatatgccga tatacggcag gtggagtcat cgacggcggt gttgtacttg
     3421 tttagcgagc gatttatgac ctatggcaag gcttatggct tatgcgaatg gttcgaggta
     3481 gagcagtttc agaacccctg aaatttcagg gagatgtcat ggatagggtg gacagttgca
     3541 gccactgcat taggggataa tcagatgtcc ttcactcgac gcaaatttgt tctggggatg
     3601 ggaacagtaa tcttttttac tggttctgcg tcttctctgt tagcgaacac gaggcaagaa
     3661 aaggaagttc ggtatgccat gattcatgac gagtcacggt gcaatggctg taatatttgc
     3721 gcccgcgcat gccgtaaaac taaccacgtc cccgctcagg gaagccgttt atcgatagca
     3781 cacattccag tcaccgataa cgacaacgaa acgcagtatc acttttttcg ccagtcatgt
     3841 cagcactgcg aagatgctcc gtgcatcgac gtttgcccga cgggggcgtc gtggcgtgat
     3901 gagcagggga tcgtgcgggt agaaaaatcg cagtgcatcg gctgcagtta ttgcattggc
     3961 gcttgtccgt accaggttcg ctaccttaac cctgtcacta aagtggcaga taaatgtgat
     4021 ttctgcgctg agtcccgact ggcaaaaggc tttccgccca tttgcgtcag cgcctgcccg
     4081 gaacacgcat tgatctttgg tcgcgaagat agcccagaaa ttcaggcgtg gttgcagcaa
     4141 aataaatact atcaatatca gctacctggt gccgggaaac cgcatctgta tcgccggttc
     4201 ggtcaacatt tgattaaaaa ggaaaatgta tgaacccgtc gcaacatgct gaacagtttc
     4261 agagccagtt agcgaactat gtgccacagt tcactcccga attttggccg gtgtggttga
     4321 tcattgccgg agtattgctg gttgggatgt ggttggtgct ggggctgcat gccttgcttc
     4381 gtgctcgtgg cgtgaagaaa tcagccaccg atcatggtga gaagatttat ctttacagca
     4441 aagcggtcag attatggcac tggtcgaatg cgttactctt tgtattgttg ctggccagtg
     4501 ggctgataaa tcactttgcg atggtgggcg caactgcggt taaaagtctg gttgcggtgc
     4561 atgaagtttg cggatttttg ttactggcat gctggctcgg ctttgtgctg atcaatgccg
     4621 ttggggataa tggtcaccac tatcgcattc gtcgtcaggg gtggctggaa cgagcggcaa
     4681 aacaaacgcg attttatttg tttggcatta tgcaggggga agaacatcct ttcccggcaa
     4741 caacccagtc taaatttaat cccttacagc aggtcgccta tgttggtgtc atgtatggat
     4801 tgctgccgtt gttactattg acggggctgc tgtgtctcta tccgcaagcc gtgggagatg
     4861 tgtttcctgg cgtaagatac tggttattgc agacacattt tgctctggca tttataagcc
     4921 tcttttttat cttcggtcat ctttatcttt gcaccacggg gcgtacgcca cacgaaacct
     4981 ttaaaagcat ggtcgatggc tatcaccggc actaacgaat gatcattaca caagcagacc
     5041 tgcgagaatg gcgtatcgga gcggtgatgt atcgctggtt cctgcgccat ttcccacgcg
     5101 gcggtagtta tgccgatatt catcatgcac tgattgagga aggatatacg gactgggcgg
     5161 agagtctggt tgagtatgcg tggaaaaaat ggctggcgga tgaaaacttc gcgcatcagg
     5221 aagtttcctc tatgcaaaaa ctggccacag cccccggaga gagaccattt tgcagtcagt
     5281 ttgcccgcag cgacgatcat gctcgcatcg gctgttgtga ggataacgcc agaatcgcaa
     5341 ccgctgggta tgccgcgcaa attgccagta tgggttatag cgtgcggatt ggaagtgtcg
     5401 gctttaacag tcacattggc agctccggtg aacgcgcacg ggttgctgta accggtaatt
     5461 cttcgcggat aagcagcgct ggagatagca gtcggattgc gaataccgga atgcgagtac
     5521 gcgtttgtac attgggtgaa cggtgtcatg tcgccagtaa tggtgacctg gtgcaaatcg
     5581 ccagctttgg cgcaaacgcc agaattgcca acagcggcga caatgtacac atcattgcca
     5641 gcggtgaaaa ttcaacggta gtgagcacgg gcgtggtcga ctcaattatt ctcgggccag
     5701 gaggaagcgc cgcactggca tatcatgacg gcgaaagagt tcgcttcgcc gtcgccattg
     5761 aaggtgaaaa caatattcga gccggagtcc gctatcgtct taatgaacag catcagtttg
     5821 ttgagtgctg atagctttac ctttaatcaa acgaaagacg ccgacgagca cgggatgcag
     5881 gctttacgac cgcccgagcc atcgcctcac caatttctgc acatgccgta agtccctgaa
     5941 cgaaaggctg gtcgtgcatc aaccagggca acgcgccgaa cgctacgcgc ccacgaatat
     6001 cttcgggttg ctgtaacgta taatcttcgc caacatcagg gatttcatcc cctgttttct
     6061 gtaattgctc gcgtagccca gggaaaggga tatctttcac tttaagcgga cgttgtccgc
     6121 gggcatcaat aaaaacgtca aacgagtagc tgttgtcttc cgttttcagg acggtgcgcg
     6181 actcattaat ttccattttg tagtcttcac cgagggcgag aatatgaatg attcccgctt
     6241 cacgtaaggc aagtaggcga cgaatagact ctgaagggat tgccgcataa ttatcgatga
     6301 aaacccgggc aaggccttta ctgaaccgtt tatggtcgtg ttcattcaga tgtggaacaa
     6361 tttcctgtac ggcttcatgc aggcgcagaa tgacataacg ccagggaaca gtatgttttt
     6421 ctcgtttatt gcgttcgact tcctggagat ttttttctgc ccagtcaaat gggtcgcgtt
     6481 gtttgcgctc ggcaaaccag gcttgagcaa aggaatcgac attcaggctc tctaaggcta
     6541 tgcgttgact ccagtctgga tcagcaaact tgatttcctc tactatcaat ctaaataccc
     6601 gatccaaaag gccctcttcg cctttttgaa tctcagcatt taatgcctga tcggtgacga
     6661 tgtgtaaggg ctcgtaggga atagggcaat agaaatcggc ttcgggtaaa atacccgtgc
     6721 gcgacaacaa cgtgatattt agcttttcac ttgcgttatc gcggtgaaaa acgacgtgtt
     6781 gtttatcatc ttcaatgaac gaaccatgct gaatagccac tgccattgcc gcatccagtc
     6841 cgctcaagga tgttcccata atacccacgt tacacgcatc gacctttgct tccatcaggc
     6901 ctgaccacgg gctgggaaaa tacgttcggg ttgcttcttc ttcatcaggc cagacgtgac
     6961 ccgtggcgat caccgctaaa tcaaacgtct cgctgggtaa atcctgattt gtagcgagca
     7021 tgacgccagc atttgtaatt tgcagatcgg taacctggca tgattcataa acagccactg
     7081 caaatttttg ctgtcgtgcc tggtctacta gtcgtaaaaa ttgatcgcgg aaatattcgc
     7141 ccagcagaat tcgcggtaaa aactgacgat cgtgcaaggt ttctttttta acgccataac
     7201 gctggagatg gctgtcttct tgcttttgta gccattcgag atacgtacaa taaatcggcg
     7261 gtatttcaat actggcaata tttgccagca tcatttttga gttttcctca tcactgtatg
     7321 gcatcccgac accggcctcg tcagcctgct cgaagataga aatagaaagt ggagtttgtt
     7381 gctgtagaag cgagaataag gtgtagatcc ccgtaggccc ggcacccaca atagcaattt
     7441 ttttcattgt tacttacctg tacgcattct ttcgaattta gtgttatcag ataagtttgg
     7501 ttgagatttt tagaatttga gaaatttcag acagggatga aaagggcgct aaccgccctt
     7561 gattaaattc tgtcaggcga gttttgcctg attgatttga ctaagtggct cattgacatc
     7621 gaaaactttg gcgacaactt cctcaacgcc gagatttttc agtcgggcag tatgtttttc
     7681 cagataggca agggcgcttt tttcatcagt gaaaaggtag atcccaccgg cttcgtggtt
     7741 cttttcactt tctgtccata ccttccacag aaaaccaggt tcctgattaa tcgactcagc
     7801 aagtggttta agctgctcag ccattgcgtc gccaaatggg ccattaaaag caaaatgaag
     7861 ttgtaacaaa gttgccatag cgattctcct tctgataacg catacgaaga cagtgtaaat
     7921 cttttaacgt attggataca gagaagaaac agagggaaaa aggagaagac cagattaaga
     7981 aaatctggtg cgtccgagtg gactcgaacc accgaccccc accatgtcaa ggtggtgctc
     8041 taaccaactg agctacggac gcaggatggt gcgttcaatt ggactcgaac caacgacccc
     8101 caccatgtca aggtggtgct ctaaccaact gagctatgaa cgcaacgttg taggtgacaa
     8161 cggggacgaa tattagcggc agagtgggaa ggtggcaaga ggcaaaacgt aattttctgc
     8221 gctatttcga ccgtttgcag agcttttaag caaattggct atattttgtt gatttgcaag
     8281 ggtgattttt attcaggatc gcatttacat ctgatacaac ccaataattc gtgtatcaga
     8341 gtttaaacag agttgtttgc caccatctca aatctgtcgt ggataaatcc tccgtagcct
     8401 ttacacttag gtagcaataa aggcacacag atgcagcaaa ggaataaatc atgggatctg
     8461 atgcgaaaaa cttgatgagc gacgggaacg tgcaaattgt taagaccggc gaggtcattg
     8521 gcgcgacgca acttactgaa ggcgagttga ttgttgaagc tggcggaaga gccgaaaata
     8581 ccgtggtcac gggggctggc tggttgaaag tggcaaccgg tgggatcgcc aaatgcacac
     8641 agtacggtaa caatggcacg ctatcggtca gcgatggtgc cattgccaca gatattgttc
     8701 agttcgaggg tggcgcaatt agtctctcta cgctcgctac ggttaatggc cgccatcccg
     8761 aaggtgaatt cagcgttgat aaaggttatg cctgcggttt gttgctggaa aatggcggta
     8821 acctgcgtgt actggaagga catcgcgcgg aaaaaatcat tctcgatcaa gagggcggcc
     8881 tgttggttaa tgggacaacc tcagcggtcg tggtagatga aggtggtgaa ttgttggtgt
     8941 atccaggtgg ggaagccagc aattgtgaga ttaatcaggg cggcgttttt atgctggccg
     9001 ggaaagccag tgatacgttg cttgctggtg gcaccatgaa taatctcggt ggtgaagact
     9061 ctgacactat tgttgagaat ggatccattt atcgtctggg gacggatggc cttcagctct
     9121 acagttccgg taagacgcaa aacctgtccg tgaatgtggg tggtcgggct gaagtgcatg
     9181 ccggtacgct ggaaaacgcg gtaatacaag gtgggacagt gatcctgttg tcacccacca
     9241 gcgcggacga aaattttgtc gtagaggaag atcgcgcacc ggttgaactg accgggagtg
     9301 ttgcattact ggacggcgct tcaatgatta ttggttatgg cgcagagctg caacaatcaa
     9361 cgattactgt acagcagggc ggtgtgttga ttctagacgg cagtacggta aaaggtgaca
     9421 gtgtcacttt cattgttggt aacatcaatc tgaatggtgg aaaactgtgg ctgatcactg
     9481 atgcggcaac gcatgtgcaa ctgaaagtga aacgcctgcg cggagaggga gcgatttgcc
     9541 tgcaaaccag tgcaaaagaa atttcacctg acttcatcaa tgtgaaaggg gaagttaccg
     9601 gggatataca cgttgagata acagatgcca gtcggcaaac tctgtgtaac gctctgaaat
     9661 tacagccaga cgaagacggg attggcgcaa cgctccagcc tgcgtaaaaa tacaggcgca
     9721 acccgtgaag gttgcgcctt gtctttatta gcgggatgct cgttgcagaa tgatggctga
     9781 cggcagacgt tgcaggaacc gcatacgcaa catcatcata atggctgccg acgtcaggcc
     9841 aataataaag cctatccaga agcctgctgg ccccataggt tcaacgacca gatcggtcag
     9901 tgccagaata tagccgcttg gcaagcccag cacccagtaa gccgtaaagg taatatagaa
     9961 aatggaacgc gtatctttat aaccacgcaa aatcccactg ccaatcacct ggattgagtc
    10021 agaaatctga tataccgccg ccagcaacat caaatgcgca gccagcgtta caacctcggg
    10081 attgtcgttg tacaacaggg cgatttgctc ccgcagtgaa accgtgaaaa tggccgtcag
    10141 ggttgccata cagacaccca ccataagccc ggtccgcgca gcggtttgcg catccagcgt
    10201 tgagccctga cccagacgat aacctacgcg gatagttacc gctgccgcca gcgacattgg
    10261 aagcacgaac attagtgaac taaagttcag ggcaatctgg tgtcctgcga catcaacaat
    10321 accgagcgga gacactaaca gagccacgac ggcaaacagt gtcacttcaa agaacagtgc
    10381 cagcgcaatc ggcaaaccga gttgaatcag tcgtttcata accgcaggat cgggttttgc
    10441 ggtgcctttt tcgttacgaa tatcgcgcat ggagcgggcg cgtttaatgt aagaaaccat
    10501 ggcaaggaac atgacccaat acaccgccgc agtagccacg ccacaaccaa cgccaccgag
    10561 ctcaggcata ccgaaatgac cataaataaa gatatagttc accgggatgt tcaccagcag
    10621 gccgataaag cccattacca tacccggctt ggtttttgcc agaccttcac actggttacg
    10681 ggcaacctgg aagaacagat atcccggcgc gccccacaac aacgcacgca gataacccac
    10741 ggctttgtcc gccagagccg gatcgatgtt ttccatggag cggataatgt aacctgcatt
    10801 ccacagcacc agcataatga gaacggaaac aaaacctgcc agccagaaac cttgtcgcac
    10861 ctgatgcgca atgcgctcac gtcgaccgga accatttaat tgcgcgataa ccggcgttaa
    10921 tgccagcagc agtccgtgac caaagaggat cgccggaagc cagatagaag taccgatagc
    10981 gaccgccgcc atgtcggtgg cactatagcc gcccgccatc acggtatcga caaaacccat
    11041 cgcagtttgg gcgatttgcg cgagaatcac cgggattgct aatgctaata acagacgcgc
    11101 ttcactgata tacttctgca cgtgaacacc ttttatttgt agttatatga gagactaaaa
    11161 agccgcctga atgggcagca aaaagaagaa gcaggggaaa ttcagtctat tgtagcgagg
    11221 atttattaat tctccagtga aaaaatagcc attcttaccc cttcactggt aagggcgttt
    11281 tccacctgct attgtgctga acagaatgtc ttaactgatt tcaggagttg taagtatgtt
    11341 tacggggatt gtacagggca ccgcaaaact ggtgtcgatt gacgagaaac caaattttcg
    11401 tacgcatgtg gtggagttac ccgaccacat gctggacggc ctggaaaccg gtgcttccgt
    11461 ggcgcataac ggttgctgcc tgaccgtgac ggaaattaac ggcaaccatg tcagttttga
    11521 cctgatgaaa gaaacgttac gcattaccaa tcttggcgat ttaaaagtgg gggattgggt
    11581 aaacgttgag cgtgcggcga aattcagtga tgaaattggc ggacacttaa tgtcaggtca
    11641 tattatgacc actgctgaag tggcgaaaat attaacctca gaaaataatc gccagatctg
    11701 gtttaaagtc caggatagtc agttgatgaa atatattctg tacaaaggat ttattggcat
    11761 cgacggtatt agcctgaccg tcggcgaagt cacgccaacg cgtttttgcg tccatttaat
    11821 tccggaaaca ctggaacgca cgactcttgg gaagaaaaaa cttggcgcac gcgtcaacat
    11881 tgaaatcgat ccacaaactc aggcagtggt agatacggta gaacgtgtgc tggcggcacg
    11941 agaaaatgcc atgaatcaac caggcacaga agcctgatct gaaatcgccc ccggagaggg
    12001 ggcgatagaa tagcctttag cgagccactc gaaggccgtt ttcaacaccg cgtgagaaca
    12061 cgacctgcca gagctgaata tcacgggcgc ggaaagcacc tgcacaggca ttcagataat
    12121 aggtaaacat tcgtttaaag cgttcactat agttatccgc aatttctggc catgcggcga
    12181 ggaatcgttc ataccacgcc atcaacgtag tatcgtaatc agcaccgaag ttatgccagt
    12241 cttccatcac aaagtggggt tcgctggact gagcaatctg gcgtacagag ggcaggcaac
    12301 cgttcggaaa aatatattta ttaatccagg gatcaacatt cagatcggtt tttttcgaac
    12361 cgatagtatg gagcaggaat atgccttccg gtttcaaatt acgatccacc accgcaaaat
    12421 aggtatcgta atttttcggt ccgacgtgct cgaacatccc cacagaaaca atacgatcaa
    12481 actggtcgtt caggtcacga taatcttgca gcaaaatggt gacatccagg ccttcacagc
    12541 gttcctgagc cattttttgc tgttcggcag aaatggtgac gcccaccacg cttacgtcat
    12601 aattagatgc catgtagtgt gccagtccgc cccagccgca gccaatatcc agtacgcgca
    12661 tccctggttt taactgcaat ttttcacaaa tcattttgag cttcgcctgc tgggcagatt
    12721 ccagattatc ggcatctttc cagtaagcgc aggaatattg catgaaggga tcaagcatgc
    12781 ggctgaacaa gtcattaccc aaatcgtaat gctctttgcc gactatccag gcacgttttt
    12841 tactctgcag attgaagaga cgagcgccgg caatacgcag cgtgtctttg aaatgatggg
    12901 ggagttggtt ctcgagacct gcgcgtaaga ctttgctaaa aaacatatcc agtcggtcac
    12961 attcccacca gccatccata taactttcgc ctaaccccaa agagccttct tgcagaacgc
    13021 gtttaaaaaa atcggggttt ttcacacgaa tatccgccgg ggcagaaccg ttaatggcta
    13081 taccggcacg gctaagtaat tcgttggcga tacggtacca gttgtcatcc ggtacactga
    13141 cttcttctat acacgatgaa ctcatagttt ctccatcact ggtcggtgat cagaacctta
    13201 aaacagcgta gacgcttttt gggctttgtg agaaatctcg cagaaaaaac cgcgagtcta
    13261 taatccgacg tagaacagag ggaaaggagg aacccttgcc gaaatgacta tccatagtga
    13321 gtcgggaacg atcctgtccc cgtaaaaaca taatatttat cgtagcttta acaactcgaa
    13381 attagtatag gccgctaatt tcaatcatac aacaaaattt tgttagcagc ctaagtataa
    13441 gtatatcgat atagatcagt gtgattcgct atgagcgact tcggcattgc catgattctg
    13501 gcagccaact tcttcacaac gttgcatcat gtaacccagc gcgaccagca ctactgttga
    13561 taacatcacg ctggtggtgg tgagcaatgg cgtgctgata ctgatcagcc aggaaactac
    13621 cagacttgcg aggaagcaca gacccagttg aagagtgttc tgcaacgctg cggcgcgacc
    13681 agttgcgtgt gggaagggac gcagcgcctg ggcgacaaca atagggtaga tcgcgccatt
    13741 ggcaatcgcc atcacacaga atgggatcag gatttcgacc agcgacacat ggctaatgaa
    13801 gcccgcagcc caggtcgcaa tgacgctgac agcaaacagc accagcaacc acggtaataa
    13861 ctgcttgcct tgccatttct gcagcgcggc gcgacagcca taaccaccaa tcagaaacgc
    13921 gatagtttgc gggacataac ttaaaccaat aactgccggg ctgtagccca tttcactaag
    13981 gatgaacggt gaaccggtca gccatgcaaa aaaactggct gaacaggctg cgtatatcag
    14041 cacgttgccg cgataggttt tagaacgtag caggtcggta aaggtcagac catcctgact
    14101 attgttacgg gccttcgtcg tgggtttgag ccagaaaata ggcagaatca gcaccacggt
    14161 aatggcaaac agggtggcga aaatcgcctg ccaggaaaaa tggaccagca gccagcttcc
    14221 taacagagga gccagtgccg gagatagacc caccagcggc atgatggtcg caaaaatacg
    14281 gttaactttc tgtgaaggat aataatctgt cactaatgct tgccagataa ccgccgcggc
    14341 gcagacaccc acagcctgta caaaacgcaa taccagcagc gtagcggcgt tttctaccca
    14401 cagcatcccc agactaccta acgcaaaaat tgtcaggccg attaataata ccagtttacg
    14461 accataacgg tcggagagcg gcccccacag aagctgggct gcggcaaaac cggcaaggaa
    14521 cagactaagg ctggcactga cagcagacgc aggcgtttgc aggtcggcct gtatggcggc
    14581 gaaagcaggc agatacatat cggttgccag aaaaccgagt acgctcaaac ccgccagcca
    14641 gactaaaaat cttttcccag gttgcatgta tattctctaa atctctcaat taaacaccgc
    14701 cgcaaagtgt agggagtgaa attagtgttg tgaaacggta atatttgatg actggtttca
    14761 aaaattttgc aggcagacta tgtggtcaga atattcactc gaagttgttg atgcggtagc
    14821 gcgtaatggt agttttagcg ctgcggcaca ggagctgcat cgcgttcctt ctgcggtcag
    14881 ctataccgtg cgtcagctgg aagagtggct ggcggtgccg ctctttgaac gacggcaccg
    14941 tgatgtggag ctgaccgctg ctggagcgtg gtttctcaaa gaagggcgct ctgttgtcaa
    15001 aaaaatgcag atcacccgcc agcaatgtca gcagatagcg aacggctggc gcggtcagtt
    15061 agctatcgca gtggataata ttgtcaggcc agaacgtaca cggcagatga tcgttgattt
    15121 ttatcgccat tttgatgatg tcgaacttct tgtctttcag gaagtgttca acggtgtctg
    15181 ggatgcgctt tccgacgggc gcgtggaact ggcgattggc gcaacacgcg cgattccggt
    15241 aggcggtcgt tatgccttcc gggatatggg gatgctaagc tggagttgtg ttgttgccag
    15301 tcaccacccg ctggcgttga tggatggccc gttcagcgat gatacgttgc gcaactggcc
    15361 gtcgttggtg cgcgaagaca cctcgcgaac gctacctaaa cgtattacct ggttgctgga
    15421 taaccaaaaa agagttgtcg tgcctgactg ggaatcatcg gcaacctgta tctcggcagg
    15481 attatgcata gggatggtgc caacacattt cgccaaaccg tggcttaatg aggggaagtg
    15541 ggtagcatta gaactggaaa acccctttcc ggattcggca tgttgtctga catggcagca
    15601 aaatgatatg tcgcctgcgt taacctggtt gcttgagtat ctcggcgata gtgagacgct
    15661 gaataaggag tggctgcggg agccggaaga gactcccgca acgggtgatt aacgacgata
    15721 gtcgcggaac gggccgtcag ccacggagcg gcgttcaatc aagcgcggat gcacttcaat
    15781 agactgcggt tcttcacgtt tgttgacgat acgatccaac agcatgttga acgctgtttc
    15841 acccagcgaa tcttttggct gatggatcgt ggtcagcgcc ggcgtaaaat agcgcgcgtt
    15901 gcgcacgtta tcataaccga tcagcgaaac atcctgcggg acgcgcaggc ccatttcatc
    15961 agcagcacaa agtgcgccca ttgccatgat atcgccacca cagaagacgg cagtagggcg
    16021 atgcggctgc gacaggattt gctgcatggc gcgataaccg gattcaggtt caaagtcacc
    16081 ctgcacaatc cagctttccg gcaccttgat catcgcttct tccatcgcct tcataaaacc
    16141 ggcaaggcgg cctgcgccgg tgttacgttc cagcgggccg gggatgacgc cgatttcgcg
    16201 gtgaccgcgt tcaatcagat aacgcccggc catgtagccg ccttcgaacg cgttatcaat
    16261 gaccgcatcg gtgaagtcag cttttgcttc accccagtcc atgaccacca ttgggatatg
    16321 gcgatactct tccagcatcg ccagcaacgg ctctgggtac tcagaacaca tcaccagcag
    16381 accatcgacg cgtttttgcg ccatcatcga cagataagcc cgctgtttct caagattgtt
    16441 ccacgcattg cccagaatca gggtgtaacc tttctggaag caattttttt caactgcttc
    16501 aatgatctcg gcaaaatagg ccgcttcgct gctggtcgcc agcaaaccga tagacttggt
    16561 gtggttaacc ttcaggctac gcgccaccgc gctaggggag tagtgtaatt ctttaatcgc
    16621 tgcccacacg gcgttgcgcg tttcttcagc gacgaaacgt gttttgttga tcacgtgtga
    16681 cacagttgta gtggaaacgt ttgctcgttt cgctacatct tttattgttg ccattccatt
    16741 tcactccaga ccctaacttc agctcctgca aaatcgcaag gtaaacgttt gcctttacac
    16801 accttacgca caacaaaagt gttgcggtac gccggaaaaa cgacacggag cgtcaggaag
    16861 gggtcaatgg ccagtacgca aatagtgtaa gcgtggaatt ttggccgatc ttgacgaaaa
    16921 ggggaagtgg taaaaacact tatcattata aatgacggga gattttttca tcacagtgtg
    16981 taaaaatgcg taatatcact ttttgtgtgg taataaaaaa ggagaaaact tgatgagcac
    17041 cgaccttaaa ttttcactgg taacaacgat tatcgtcctc ggtttgatcg tagccgtggg
    17101 tttgactgcc gcgctgcact gatttcctct cgagggagcg cgttctccct cgcatctcct
    17161 tcctgtttgt tagcaaaatg gcaaaagtgt tttctctttt tgttattttc atttttttgt
    17221 gattgctgtc atgctttcgc cactttaatg aatatcgcgt aatgacgcga agaggtggag
    17281 ataaggcatg aaaattaact atccgttgct ggcgctggcg attggcgcgt ttggtatcgg
    17341 gacaacggag ttctcgccaa tgggcttgtt gcccgtcatt gcgcgcggtg tggatgtctc
    17401 gattcccgct gccggaatgt taatcagtgc ctatgcagtt ggcgtaatgg ttggcgcgcc
    17461 gctgatgacg cttctacttt ctcatcgtgc ccgccgcagt gcgttgattt tcctgatggc
    17521 aattttcacg ctcggcaacg tactttccgc catcgcgccg gattatatga ccctgatgct
    17581 ttcacgcatt ttgaccagcc tgaatcacgg agcatttttt ggtttgggtt cagtcgtggc
    17641 cgcaagcgtg gtgccaaaac ataaacaggc cagcgcagtt gccactatgt ttatggggtt
    17701 aaccctggca aatatcggtg gcgtgccggc ggcgacctgg ttgggtgaaa ccatcggctg
    17761 gcggatgtca tttctggcaa cggcggggct gggagtgatt tcaatggtaa gtctgttctt
    17821 ctcattacct aaaggtggtg caggggcacg acctgaagtg aaaaaagagc tggcggtatt
    17881 aatgcgtccg caggtgctgt ctgcattgct gacgacggta ctgggagctg gtgcaatgtt
    17941 tactctctac acctatatct ctccggtact gcaaagtatt acccacgcaa caccggtgtt
    18001 cgtcacggca atgctggtgc tgattggtgt cggattctct atcggtaact atctcggcgg
    18061 caaactggca gatcgttcag ttaacggcac gttgaaaggc tttttgttgt tgttgatggt
    18121 gattatgctg gcaatcccgt tcctggcccg caatgagttc ggcgcagcta ttagcatggt
    18181 ggtgtggggc gcagcaacct ttgcggtcgt accgccgtta cagatgcgcg tgatgcgtgt
    18241 cgccagtgaa gcgccaggtc tgtcttcatc agtcaatatt ggtgccttta atcttggaaa
    18301 tgcgctggga gcagctgctg gtggtgcggt aatttccgct gggctgggat acagctttgt
    18361 gccggtgatg ggagcgattg tcgcgggact ggcattattg ctggtgttta tgtcagccag
    18421 aaaacaacct gaaacagttt gcgttgctaa cagctaatta aacaaaaacg cagaaggata
    18481 accttctgcg ttacagttgc tgacaacgtg cgatttatct tgccggatgc ggtgttaacg
    18541 actcatccgc gttgacatga aaagacgcgt taggcgtcgt atcatgcagc gcttgtcgga
    18601 tgcggcgagt gccttatccg acctacatcg atgatccgcg taggcctgat aagcgtagcg
    18661 cttcaggcaa tgctgcatgt gccatcagtt attatgcagc gagatttttc gctacgaatt
    18721 cccagttcac cagcgcccag aagtgctcca gatagccagg acgtgcattg cgatagtcga
    18781 tgtaataagc gtgttcccag acatcaacgg tcagcagcgg agtcgcatcg gtggtcagcg
    18841 gagtacccgc gttagaggtt gaaacgatag ccagtttgcc atcgctgttt ttcaccagcc
    18901 aggtccagcc agaaccaaag tttttgatcg ctgcatcagt aaactgcgct ttgaaatcgg
    18961 caaagctgcc aaaagatgcg gcgatagctt cagcgacttt tccagtcggt tcgccaccgg
    19021 cgttcggtgc caggcagttc cagtagaaag tatggttcca gacctgagct gcgttgttga
    19081 atacgccacc ttcagagctg cgaataatct cttccagtga tttaccttca aacgcggtac
    19141 ctttaatcag gttgttcagg ttagtgacat aagtctgatg gtgcttgccg tagtgatact
    19201 cgatggtttc cgcagaaatg tgcggtgcca gagcatcttt agcatatggt agtgcaggta
    19261 attcgaatga cattgctact ctcctttatt attaatttgc atacgtacaa tagccttatt
    19321 gtgcgtatgg atagggtagc aaattaaaag gtgagacaaa agatgaactt accctgttgc
    19381 cgtaacaaca gggtaaagtt ttagcgaagt gtttttgggg tcattacccg acgagcgcca
    19441 acatagtggc gctgccagta gtcttcactg agagaagtga tttgaatttc ctgacctgtg
    19501 cgcggtgact gaataaattt gccgttgccg acatacacgc cgacatgatc ggctgtgccg
    19561 cgtccctgag tacggaaaaa gaccaggtcg ccgtttttca gttcactacg ttcgattggc
    19621 gctgcatcac gcaggtgata catttcattc gccgtacgcg gaatacgaat tttcaccaaa
    19681 tctttataag cgtaataaac caggccgctg caatcaaaac cggtacgcgg tgagctgcca
    19741 ccccaacgat atggcttacc aatttgctgc atcagtttat tcattgccac tttcgtagct
    19801 ttttgcacct tcgctttgtg cgcgtcggca agagttcctg acgcggcatt tttgactttc
    19861 acacaatgcg atttatagcc cttacgtttg gtacactttt cggtaaagct ggctgaggcc
    19921 gttttattga cggcgtgttt gctgcgagtt ttggcgtttt tagaagcggt aatggaagat
    19981 tttttaacgg aagaagcggt tttgcttttg gtcgtacttt tactggcggc ttttttcgct
    20041 gttttctggg tctttttggt ggttgccgtg cttttctttt tatctgcttt tttggtgata
    20101 tgagtggtag cagaactctc cctggcttgc tttgaagcat gggccatagg cgttaaaggc
    20161 agggtggtaa aaagtaaagc acagagcgtg atcgaaatac ggtttatccg cgccactgag
    20221 cgtccctctg ttaaggcagg tctatcatgc ctgcgtctga tttacaaaac ttgatgattc
    20281 taatgcatag aagaagagaa agttaatagc ttttattgtt aaaaaatacg tttcgttggc
    20341 gagcgcaaaa aaatgcagca gtgaaagcta aaaatggtta taaatacgcc agtttgccgg
    20401 catcagagaa gaaacgaata tttgaaatgc aacaaataga gcaaagggat aaaatagcaa
    20461 aagcgtgatg aaaatgttat tttccgatgc cgcactgacc cgctacaatg tcagattact
    20521 gccgtaaaga agtttgagga agcaagacaa tgagcaccac tatcgaaaaa atccaacgcc
    20581 agattgctga aaacccgatc ctgctgtaca tgaaaggttc accgaaactg ccgagctgcg
    20641 gtttctctgc ccaggcagtc caggcgcttg ccgcatgtgg cgaacgtttt gcctatgttg
    20701 atattctgca gaatccggac attcgtgcgg aactgccgaa atatgctaac tggccgacct
    20761 tcccgcaact gtgggttgac ggcgagctgg tcggcggttg tgatatcgtg atcgaaatgt
    20821 atcagcgtgg cgaactgcag cagctgatca aagaaactgc cgctaaatac aagtctgaag
    20881 agccggacgc ggaataatcc gtcctgcaat actgacggat gcgaacgggc atccgtcagt
    20941 cctttctcta tccccaatcc agcccttgtg gcgaacttga aaatcccgcc tcacgcagca
    21001 gcgtaaacat cggcgtttgc cggacaggta gatcattcac ttctgttagc gtaaagcgca
    21061 gccgtggttc gcgacgcagt gcggtagtca gcgcgtggaa aacctctggg gcgagtaatt
    21121 cctctttttc ctgccagacc agcatttttt tgccaccttg cgccagatag agtaacaatt
    21181 tgccgccaga aacgaccacc agcgcacccg cccgacgcgt tggaaccagc gttgccggat
    21241 gtgcaggcca gggcagaaga tttccccaca cattagccgg atcgttggca gagagcgcca
    21301 ctggtgtata gtggcgcgtt tgcgtggctt gtgtcgccag atcgcgcaat cggtcaatag
    21361 tcagacgttc agcgaattgc gcgccaccca gaccttctac aaaacgacct cgcataattc
    21421 gcccggagtc ttccatactt cgacaaagcg tttgcatcga tggaaacccg ccagggatat
    21481 tttcggctat caccgcctga cgactgatga tgccgtagcg gtcgagcata ttttccgcca
    21541 gcgccagcat cctttcggta tcgtttagtg gctccacctg caataacgac cagcgtccag
    21601 ccagatttgg tgtgttgtaa gatacccgcg gcgagacggg ttgcgcatag acaggacgtc
    21661 cacgacgagc ccggtgactg cggcgagttg aggtgcgtgc gttggaactg ctgcgggtga
    21721 gggcgcgtaa cggtgcccaa atgtcgctgg tgatgacgcc ttgccagacc agcgcccata
    21781 acgcctcttg cagggcagag agatcaaccg attcgccgat tttgtcgcgt atccgttggc
    21841 tgatttgttg tgcaaaccag gctcctccgt cagccagaac agcgactatc gcttgttgca
    21901 gcgccgaacg attcgcctga tccgcttcgg cgggagtgaa cgattctgca gcatattcct
    21961 gtagatgcag tgccaccagg ccgtcatctt cacccagttt tttttgcccc gaccagataa
    22021 ccgcaccggt tgccagtaat tcatcgagca tttctgacga atagtcgcgt acgcgggcag
    22081 gcaggatctg gctttcccag agtgaggcgg gtaaaccgac tccggcaagc tgttcgatca
    22141 cccgcatcac gccatctacg ccctcataaa cgcctggcga tgttgaggca aagagcgccg
    22201 ggctaccatc ggtggcgggt aatacgccct gacgttccag cagcaatcgc gcataggtcg
    22261 tggctgcaac gggacgcgtc gcttctctgg cggcttgcag cgagcgcaaa cgcagacgac
    22321 gaaatacttc atcgctcacc cagatgtctt gttgcagatt catcaccaga ccctgttcac
    22381 gcagttgctg aagctgctct tcgacaatgg caataccgag actaaactca tgagccagtt
    22441 gttcagccgt gaccagagca tgagcccgga gatagcgcag aaagaggtcg cgaagcgggt
    22501 aactgactct atgtaaataa atctctggca atgactctgg tagtcgtacg ccgagggcat
    22561 cacgcagcct ggcggcatca tccatacagg caagacgctc ctgtccgcta atcatcgctg
    22621 ggaagattcg ttttactgca agaagatttt ccagatacga cgcaacctct tcactgctgc
    22681 ctgtatgccg ttgcgccagg tcttcaacgg tcattggccc cagttcgcgc agcaggtcga
    22741 acaatccttc ttcacctttc gctcttctgc caggagccag tcgttgcaac tcttcttcca
    22801 cctggcgaat gacctgcggg tcgagtaatt cccccggatc gacctgtccg agtagattgc
    22861 gcagtaactc gctgtccagc gacagtacgg atgcccggcg ctctgccagc ggggcgtcgc
    22921 tctggtacat aaattccgcg acatagccga acaataaact tgtggcgaaa ggcgagggcg
    22981 tagtggtcgt tacatcggat atttgaattt cgccaccgtt caggcgacgc atcaaacgtt
    23041 ccagtgcggg aagatcataa acatcttgca gacattcgcg tagggtttcg agaatgaccg
    23101 gaaaatccgg atatccctga gcgatttcca gcaactgact ggcgcgcagc cgttgttgcc
    23161 aaagcggggt gcgatggccc ggagtgcgcc ccggcattaa taatgcccgc gcggcgcatt
    23221 cgcgaaaacg ggcggcgaaa agtgccgagc tgcctaccgc ctcgcggaca atttgcagca
    23281 acttttctgg ttcaaacaaa aaaatcgcgg catcgggcaa tttaccatcg gtgtcaggaa
    23341 tacgtgcaac aatgccgtca tcactggcga ccaccgacgc gtcagcgccc catagcgcat
    23401 gtattcgccc ggcaatcgcc accgcccagg gttcatgcac ccgtcttcca tagggagagt
    23461 gcaaaataat acgccagtca ccaatttcat cacggcaccg ttcgaggacc agatggcgac
    23521 tccccggaac gatgcccgtc gcgttgcgct gctcctcaat caacccctga atattggcga
    23581 tcgtattttc ttctgccagc cacgggggaa tagtcccgga aaagaacgcg ccatccgcca
    23641 gcaaatgaag aaaatcgccg atcatctcgc ctaattcagc cggacgtccg ttaccttcac
    23701 cacgccagaa ggggagccgg gcagaacgac ccggagcagg agtcacaatc acctgatcgc
    23761 gggtgatttg ctggatccgc catgaggtag cgccgagagt gataatgtcg ttcacccgcg
    23821 actcatatac catctcctca tccagttcac ccacccgccg cgaaccggcc ttttcttcac
    23881 cttcgggtaa taacacgcta tacatgccac gatccggaat ggtgccgccg ctggtaaccg
    23941 ccaacaattg agcgccaggt cgggcggtca atatcccggt ctccctgttc cagaccagtt
    24001 tggggcgaaa agcagaaaaa tcgccagagg gatagcgccc ggaaagcata tccagcgtgg
    24061 cgtcaaaaac acgtcttggc agatctttcc acggtgcggc acggcgtacg cgggagtacc
    24121 attcgtctac ctgtaatgca tccatcgccg cggcggcaac ggtttgctgc gcaaggacgt
    24181 cgagaggatt atgcggtggt gtcaggtttt ccagcctgcc tgcgaacata cactctacaa
    24241 tgactgcgga atcgactaaa tcacgccggg tacgggggaa aaacagccct ttagatacac
    24301 cgccaacctg atgtccggcg cgaccaatgc gttgtaaccc actggcaaca gaaagcggcg
    24361 ttgccacctg aatcaccaga tccaccgcgc ccatatcaat ccccagttca agactggagg
    24421 ttgcgaccac gcagcgtaat tcacccgatt tcagcgcctg ttcggtgatt gctcgttgtt
    24481 ctttagagac ggagccgtgg tgtgagcggg caataaaaac gtcgctactt tgtacacggt
    24541 tagaggttgc gccggaggtc gactcgaaat gggccgcatc aacggcgata gacggggaac
    24601 gctgtaagcg tgcggcgtaa agctcattta atcgtgccgt cagtttttcc gccagccccc
    24661 gcgaattagt aaagacaatg gtcgagcgat ggcgcaacac ttcatcaagg atacccgttt
    24721 caatatatgg ccagatggag ccttcccggc cggcatggct gtcttcgccg gtgccgctgg
    24781 cgaccgatga gacatcatcc atattggcga ccggtacgac aattcgtatc tgcggatggc
    24841 gcattgcggg cgggttgact accgtaaccg ggcgatcgcc accaagaaat gctgccacat
    24901 cgctggctga gcgcacagtg gcagaaaggc caattcgctg tgctgaggtg tggagcagcg
    24961 catcgagccg ctccagactt aacgccagat gcgcaccacg tttactgccc gctaccgcgt
    25021 ggacttcatc aataattacc gtttcgacgc cgcgtagcgt ttcgcgcgcg cgggaggtca
    25081 gcatcagata gagtgattcg ggtgtggtga tcagaatatc cggcggatta cgggtgagtt
    25141 tgctgcgttc ctgtgcaggc gtatcgccag tacggatccc tacgcgaaga ttgacttccg
    25201 tttcgccgcg ccgccgccgt tcatcggcaa tacccttcaa cgggatctgc aagttgcgct
    25261 gaacgtcggt gcccagggct tttatcggtg aaatatagag gatgcgtgag gttttacgct
    25321 tatgcgcctc gcgggtatct tcgccgcctt cgcggaagag ccgatcgagg gcgtagagaa
    25381 atgctgccag cgttttcccg gagccggtcg gtgcaatcac cagcgcatgt tcgcttcgcg
    25441 ccgccacatg ccaggtttgc ggctggacag cggtcggctg tttaaaggcg cgaagaaacc
    25501 agtcgcgggt cgccggtgaa aacacgtccg gcaggagcga tgaagggtct ggattatctg
    25561 ccattaacgc tattccccgt gaatatcatg caggatgcgt ggaatagcct cactatagat
    25621 gcctgaatca ttgcatgtca tcaggcatcg actcgattac acctcttcgg cggcagatag
    25681 cggccagcct cccagacgtt tccagcggtt gacgatttca caaaacagca cagcagtgcg
    25741 ttcggtgtcg tacagcgcgg agtgcgcctg ggtgctgtcg aagtccatgc cagcggtctg
    25801 gcaagccttt gacaatacgg tttgtccgag tgccagcccg gccagtgcag cagtgtcaaa
    25861 agtggcgaaa gggtggaacg ggttacgttt cagtgaggcg cgttctgcgg cggccatcat
    25921 aaagctgtga tcaaaattgg cattgtgcgc caccataatg gcgcggttac agccgctcgc
    25981 tttaatacct ttacgtacaa ctttaaaaat ttcgtgcagc gcctcgtatt cgctgaccgc
    26041 gccgcgatcg ggatcgttcg ggtcaatgcc gttgaaggcg agggcttctg gttgcaaatt
    26101 tgcgccgaca aatggttcga cgtggaaatg taatgtggtg tccggcatca gccagccttg
    26161 ttcatccatt ttcagggtga tggcggcaat ctcaagcagc gcatcggttt tggcgttaaa
    26221 tccggctgtt tcaacatcga tcacaacagg ataaaaacca cgaaaacggt cgcacagacc
    26281 ggtaagttga gcgttatcgg acatctgatt ctcttaatac ggataaattg cagcgcgcat
    26341 tatgacaaat attacttgtc gatgcagtaa agatgcgggc gcgatgagtt cacgcccggc
    26401 aggagattag ttgcccagac cgcgaccggc gtctttctct tcgattaact caattttgta
    26461 accgtccgga tcttccacaa acgcgataac cgtagtaccg ccttttaccg gacccgcttc
    26521 acgggtcacg ttacccccgt tttgacggat tttttcgcac gcttcagcgg cgttatctac
    26581 gctaagcgcg atgtgaccat aagcagtgcc gagttcgtat ttatccacgc cccagttgta
    26641 ggtcagttca atcaccgctt cttcggtttc cgggccgtag ccaacaaacg ccagtgagta
    26701 tttgtattcc gggttttcgc tggtacgcag cagtttcatg cccagcactt tggtataaaa
    26761 atcgatggag cgttgcaaat cgccaacgcg cagcatggta tgaagaagac gcatcttttt
    26821 atcctcaaaa tggctaacag attcaaaatg ttgttttagt atagcggcgg ctttacgccg
    26881 ctcgcaatgt tggattacaa cgtcgggtaa tcggtatagc cttccgcgcc gccaccgtag
    26941 aaactttcgg cacgctgtgg gttaagctca gctttgcgct gcaagcgggc gaccagatcc
    27001 gggttcgcaa tccagtcacg accaaatgcc accgcatcaa ttaacccttt gccgatcagc
    27061 gtttcagctt tttctactgt gtatgcacct gcgccgataa tcggaccgtg gaaacgggcg
    27121 cgtacttttt cgcggaacgc atcagtatac ggttcacccc ccgcccaatc tggttctgac
    27181 atatgcagat aagcaatgcc gcgtttaccc agttgttcaa tcagatacag tgcatcggct
    27241 tcttcattcg ggccgttatc tgtgttctgg aaagtaccga ttggtgaaac gcgaatgcca
    27301 atgcgatcgg caccccattc ttcaatcccg gcatcgacca cttccagtac caaacgtgcg
    27361 cgattttcca cgctgccgcc gtactgatcg gtacgatggt ttgaagaagg agaaaggaac
    27421 tgatgcagca aataaccgtg agcagagtgg agctctacca gatcaaaacc ggcttcacgc
    27481 gcgttagcaa tggcctgacg gaaatcattg acgatacctg gaatctcttc cagttcaagc
    27541 gcacgcggca tggatgtttc aacacggatc gcctgaccat tttcatcgcg cagagaagta
    27601 cgtgttcccg cgctaagtgc tgaaggcgct accggtgcct gaccgccagg ttgcaggctg
    27661 gcgtgagaaa tgcgtccggt gtgccacagc tgcacggcca tatgaccatt ttcagcatga
    27721 acgccagcgg tgattttttt ccatgcggca atttgctccg gactatggat gccaggcgca
    27781 cctgcatatc cttttgcctg ggcagaaatt tgcgtggctt cactaataat caaaccggca
    27841 ctggcacgtt ggcgatagta ttccgccatc aacggggtag gaatgtcacc cggttcaata
    27901 ctgcgcagac gcgtcagcgg tgccataaaa atacggtttg ccgccgtgat cgcgcccact
    27961 ttcagtgggg aatacagttt ttcagatgac ataaaggctc ccggtcgtct ggtgataaaa
    28021 aatgcctgct aaacggcagg cgtcgcaata atgtttttta catgggccag cgcgttttcc
    28081 agtggctcga aactgcgcga aattttggcc tgcagattcg cgccaagcca cagtgcgtaa
    28141 agcacttgtg cctgttgcag cggttcgcca caaaaggtta aacaatggtt ctcacggcca
    28201 ttttccagcg cctgagagag cagggcgatc acgccgcgag cacctttatc catcgcgctg
    28261 cgcatatctt ctgacagatc gcacacttcg gcagagagtt ttactgtcag gcaaccactg
    28321 atggttccat gttggcaaaa ctggttcagt gtttgctggt aataagccag tatgcggtcg
    28381 cggtagttac cttcgccgga ttgcagcaac tcagtcagtc gctggtgata tgcggcgtaa
    28441 tgacgctcaa gcatggcaac gccaaacgct tctttagagc gaaagtagtg atagaaggac
    28501 cctttcggca cttcagcggt ttttagtaat tcgcttagcc ccatcccggt gaatccacgt
    28561 tgcaggcaaa gttgctcgcc cgtcgccagg agatgttcgc gagtatcatg ttcggtgtgt
    28621 ttgttcatgc gttggagtgt agtagaccag tcggtctagt gcaagcaaag ttgctacttt
    28681 ggacattaac agcttcaata atggtaataa tcttatctga ggagggcgaa gtggcggagc
    28741 aattagagtt ctttcccgtc cagagcccgt gccggggaat ttgccagtct gacgaacgcg
    28801 ggttttgtcg cggctgtttt cgtagtcgtg atgagcgttt taactggaat aaaatgagcg
    28861 atggcgaaaa acaagaggtg ctgcgccttt gtcggcagcg attaatgcgc aaattacgcg
    28921 caaataagcc agcgtcatca gacgaaccgg agcaaccatc actcttttga acctaatctt
    28981 gcgtatactc ctctcatatc tgataagagg aagcgattat ggttcagcgt attactattg
    29041 cgccgcaagg cccggagttt tcccgttttg tgatgggcta ctggcgattg atggactgga
    29101 atatgtccgc ccgccagctg gtcagtttta ttgaagagca tctggatctc ggcgtgacca
    29161 ccgtggacca tgctgatatt tatggtggct atcagtgcga agcggcgttt ggcgaggcac
    29221 tgaaactggc acctcacctg cgtgaacgga tggaaatcgt cagtaaatgc ggtatcgcga
    29281 cgaccgcgcg tgaagaaaac gtcattggtc attacatcac tgaccgcgat cacatcatta
    29341 agagcgccga acagtcgcta attaatctcg cgaccgatca tctggatttg ctgttaatcc
    29401 accgaccaga cccgttaatg gatgccgatg aagtggcgga cgcgttcaaa catctgcatc
    29461 agagcggcaa agtgcgtcat tttggcgtat cgaactttac gcctgcgcaa tttgccctgt
    29521 tgcaatcacg tctgccgttt acccttgcca ctaatcaggt ggaaatatcc ccggtgcatc
    29581 agccgttact gctggatggc acgctcgacc aactacaaca actgcgtgtt cgtccgatgg
    29641 cgtggtcctg ccttggtggt ggtcgtctgt ttaatgatga ttatttccag ccgctgcgtg
    29701 atgaactggc tgtggtggca gaggagttaa acgcgggctc gattgaacag gtggtttacg
    29761 cctgggtatt acgtttacca tcgcagccgc tgccaattat cggttcaggt aaaattgagc
    29821 gcgtacgggc agctgtcgaa gcagaaacac tgaaaatgac ccgtcaacaa tggtttcgta
    29881 tccgtaaagc ggcactgggg tacgacgtac cgtaagcact tttaggaata gccgccgttc
    29941 aaaaatgtgt cactggttta cacttattca ggaatgcaca atgaacggag gtcctatgaa
    30001 acgttttagt ctggctattc tggcgctggt tgttgcaacc ggcgcacaag ctgccagtga
    30061 aaaagtcgag atgaacctcg tcacgtcgca aggggtaggg cagtcaattg gtagcgtcac
    30121 cattactgaa accgataaag gtctggagtt ttcgcccgat ctgaaagcat taccccccgg
    30181 tgaacatggc ttccatattc atgccaaagg aagctgccag ccagccacca aagatggcaa
    30241 agccagcgcc gcggaatccg caggcgggca tcttgatcca caaaataccg gtaaacatga
    30301 agggccagaa ggtgccgggc atttaggcga tctgcctgca ctggtcgtca ataatgacgg
    30361 caaagctacc gatgccgtca tcgcgcctcg tctgaaatca ctggatgaaa tcaaagacaa
    30421 agcgctgatg gtccacgttg gcggcgataa tatgtccgat caacctaaac cgctgggcgg
    30481 tggcggtgaa cgctatgcct gtggtgtaat taagtaatta agaggccagc gtaccttgcg
    30541 gtggtgcttg ctcaagttgc gaaagcgagc agtacagccg ccagacaatt gccgccagct
    30601 cacgggcggc aggttgatga tgacgggcaa ggctgtcgca aatccgctgt aattcttcaa
    30661 gtgtggccgc cagtgatttt tgctgaacgc cacgctcact catcactccc cgcaacagtg
    30721 aaatacagtt atcccgtact cgcgataacg gatcggaacg cgattcccag tcgcgcaatt
    30781 gccagacaac atgagaacag ttcagcagca ctacacccca gcgtaataac caacggcgag
    30841 ccagcgcatc ctggctgtta ctcaactgac tgacgtgatg ataagtgagc gattcaaatt
    30901 cgctttcact cagtgttgga tggcggctta gctgatcgac aaaatcccgg cgcagcgcgc
    30961 gaatatggcg gcggctttta cgagcatccg atcctggacg cagaatggcg aacgctaacc
    31021 acgccaacgc gacgccaacg atttttgcca gattatcgtt aagaaaatca gcaaaatcat
    31081 acaccggggg attagtgaca gcgataaaag aacccataaa aacaatcagt tgcccccaca
    31141 gtgcggcaaa ttttggcatc tgcaatttaa gaagctgcat tgtcgccagc agtggaaaga
    31201 gaaacagtaa aaattgccac agatcgctaa tctggaccat cagaccaaat ttgaccacaa
    31261 agctgaatag cgaaagtaac accagcgtgc gcatcagaag tgacaacgac ttaaacggtg
    31321 ctgcgacggc ggagtagagt acgcagctaa ttgctgccag cgttaatgca ttggcaccgg
    31381 catcccattg cgaagcaata ctccatgcgc caatcatcat caacgtacaa aatgtacgca
    31441 gcccgctcca catagcttcg gcgttatcgg tatgacgagc caggccggat gtccgtggga
    31501 gtctggtatg atcatctaca ccgctttgca gacgatgtaa ttcctgacta ctttgcagat
    31561 aaaggcggca aaaataacgt agtcgctgcc agaaggcgac gtgccgatag tcggcgacgt
    31621 tggtcgggcg tagcggggcg ataatacgtg cgacggtgta aacatctgtt tgcgaactgg
    31681 cgagcgccgt cagcaactgt tcgagaattt ctcgtgtggc acctggcggt gagggccagt
    31741 tgagcaacat acgtcgcagg ctggagatga cactggtcat acgtaattgc tggtggagca
    31801 gcgcattaag gcgcgcgttt tgctggcgaa aacgatagtg gctccagaaa gcctggatac
    31861 gcagcaaatt catggtcagt atctgcccaa tcaccccttc atgtgctgca cgaatggcat
    31921 cggttgtttc aggctgccag agtaaactgg catgttccag taatcgggcg tgcatgtttt
    31981 tcaatgcggt taaaagggca gtagcatcgg aactgttcgg caggatcatc atcatcatgc
    32041 cgccgcacaa aataccgact attacctcgc aaacgcgcgc ctgagcgata tcccacagct
    32101 ggctggcctc agtaatatta accatcggaa aggcgatgat ggcagccgtg tagcccgcca
    32161 gttgaaatgc atacgcgacg ttattcgtga agtgcgcaca ggcccaggta caaaagccaa
    32221 gccacgccga catgctcaat agaaaaaacc acggctcatt gagcgtatgc ccggcaagaa
    32281 gcagtgccgc aatggctccg agcaaactgc cagcgatgcg tccgaggctt ttgctgataa
    32341 caccgccaac ggtgggaaag ctaaccactg cagccgaggt catcgcccaa tagggttcat
    32401 ccagatttaa ataataggca accgtcagcg ccagacacat ggcaatggta ttgcgtaacg
    32461 cataacgcca ttgcgccagc gtggccctga accagggcaa attgcgcaag gaccatgacg
    32521 atgcgttcat tattgaccta cggcaatgct acaggtggtg cccgacacca acgtgacatc
    32581 gcctgggact ttatccagcg caaagcggac gggaacgcgt tgggcgagtc gaacccaggg
    32641 gacgttaggt ttaacatccg gaataaggct tgagtcactt tcaacgctct gatcataaat
    32701 cgcccgaccg atactggaaa cgtgaccctg taacgttttg ttatcactat agagggtaat
    32761 ttgtgctggt gcaccttcgc ggatatggcg caacttggtt tcttcaaaat aaccaatgac
    32821 gtaaaacgag tggctgtcga caagggcaaa cagcggtttc ccggtatcag cgtaatcgcc
    32881 gatgcgggta gtaaggttag tcacccatcc actcaccggg gcgcgaattt ccgtttgcgc
    32941 cagttgccat tgtgcctgtt tcagcgtcgc ctgtgcggca tcaacactgg cctgcatcgc
    33001 tttaacattg aggttagcgg tatcgagttc ttcggcagaa ataaaatttt gtgagagatg
    33061 acgacgacga ttcgcttcgt tattggcttt tgcgaggtca gattgcgctt tcgccagctg
    33121 agcctgtgcg ttcagctcgg cgatctgaaa gggcgtttta tcgatcgtga gcagaagatc
    33181 ccccgcgtta accagctggt tgtcttttat attcagctca acaatacgtc ccgacacctg
    33241 tggggtgata gaaacctgtt ctgcgcgtat tttcccgtcg cgtgtccacg gagattgcat
    33301 gtaataattc cacagccacc atccggcaag aaccgcaact accgctacaa tgattgttga
    33361 gaaatactta attgttttaa ttgacatagt taccacgcaa tcagtattgc cagagcaagg
    33421 caaacgcaaa tcgcaaacag cgataaatcc attaacaagg gatgccagat gtcaccggcg
    33481 tagatccagc cacgaagcag gcggtgtacg acaagccaga tgacgaatcc aaacgcgaat
    33541 gctttgaaaa acggaggaaa gtagacggac gcaccgaaca ccagatcttg taagggcaat
    33601 cctgttgcat tgagcataaa cttcacaaag tagattcctt tacgaccgaa tatattgcgt
    33661 tagattaata aatattcttt aagtgcgaaa aatttacgcg caatttctga aaaatatgtc
    33721 tgacggtaac caaatgcagc aatacatttg ttttagcaat acaattgctg cacactattc
    33781 taaaagccgc ataatatctt agcaagctaa ttataaggag atgaaattgg aatcgccact
    33841 aggttctgat ctggcacggt tggtgcgcat atggcgtgct ctgatagacc atcgcctgaa
    33901 accgctggag ttaacacaaa cccattgggt tacgttacac aatatccatc agttacctcc
    33961 agaccagtcg caaattcaac tggcaaaagc gattggcatc gagcagccat cactggtccg
    34021 tactctggac caactggaag aaaaagggtt aatttcgcgt caaacttgtg ccagcgatcg
    34081 tcgggctaaa cgtattaaac tgacggaaaa ggcagagccg ctgatcagcg aaatggaagc
    34141 tgttattaac aaaacccgcg cggaaatatt acatggcatc tccgcagagg aactggagca
    34201 actgattacg ctcatcgcaa aacttgagca taatatcatt gagttacagg ccaaagggtg
    34261 aaatgaaggg ggcgtgtggt cagtaacctg accacacgca aacttattta gcgcggagaa
    34321 acggtcacct gactgccatt gctggccagt acgacacgtt ggcccggaga gaaacgagtg
    34381 ttgccttgtt tctgtaccac catgatggta ttaccatcgt ctttacgaat ttccagctcg
    34441 acaccctgcg ttttgttcat tgcactctgt acgccctgac cagctacgcc acctgcaaca
    34501 gcgcctgctg cagtagccag agaacgcccg gttccgccac caacagtatt ccccaggaaa
    34561 ccaccaagaa cagcaccgcc aattgcaccg ataacgttgg aatcatcacc gccctgaatc
    34621 tgtaccggac gtacgttaac gatggtgcca tagctgacat tctgtacttg tttcgcttca
    34681 gaagcggtat aaacatcccc tgacagggtg tcgttattaa cacaaccgac aagagacaga
    34741 cctaccattg aaacaaccaa tacgcgttta atcattgaaa aatctcctgt tcaccatgaa
    34801 acgccacgca agcatccctc atggtcaaag tatatggcat atgtgaatcc atggttacat
    34861 gttctaccaa atatgagcaa atcataatga aagtaggatc aaccaattat aaacaaaaca
    34921 ttcatgatga ttattgattt gaagataatg ttttactacc aacggtaaaa atcggtcatt
    34981 ccgcatggta ttcacgaaaa gtttatgttt gagtggtgcg caaacgtcag attgaaaaag
    35041 gatgaactat gaaatcgggc cgctttattg gcgttatgtc aggcaccagc cttgatggtg
    35101 ttgatgttgt gttggcgaca attgatgaac accgggtcgc acagctggca agtttgagtt
    35161 ggccgatccc ggtatctctg aaacaggctg tactggatat ttgccagggc cagcagctta
    35221 cactttcgca gtttggacag cttgatactc aactcgggcg actttttgct gatgcggtca
    35281 atgccttgct taaggaacaa aatttgcagg caagagatat agttgcgatc ggttgtcacg
    35341 gtcaaaccgt ctggcatgaa ccgacgggcg tggcaccaca cactttacag attggcgata
    35401 acaatcaaat tgtggcacgc accggaatta cggttgtcgg tgattttcgc cgtcgcgata
    35461 ttgccttggg aggacaaggc gcaccgctgg tacctgcgtt ccatcatgcg ctgctggctc
    35521 acccaaccga gcgacgaatg gtgctcaata ttggcggcat cgccaatctg tcactgctca
    35581 ttcctgggca gccggttggg ggctacgata ccggtcctgg taacatgctg atggatgcct
    35641 ggatctggcg tcaggccggt aaaccttacg ataaagatgc cgagtgggca cgggcgggta
    35701 aagttattct cccactgctg caaaatatgc tcagcgaccc gtatttctcg caacctgcac
    35761 cgaaaagcac cggacgcgaa tactttaact atggttggct ggagcgccat ttgcgccatt
    35821 ttccgggtgt tgatccccga gatgtgcagg cgacactggc agaactcacc gccgtgacca
    35881 tttctgaaca agttttgttg agcggtggct gcgaacgatt gatggtatgt ggtggaggta
    35941 gtcgtaatcc gctactcatg gcgcgtctgg cggcattact gccaggcaca gaagtcacca
    36001 ccaccgatgc cgttggcatt agtggcgatg acatggaagc attggctttc gcctggcttg
    36061 cctggcggac gctggcggga ttaccaggaa atctgccttc cgtcactggc gcaagccagg
    36121 agacggtact gggggctatt ttccccgcta acccgtgata tcagagttaa ctgaattttt
    36181 cttaccgcgt ctgccgttac acttggaacg ttagggaggg cgtattgccc tccagaccag
    36241 gaaagtcttc gggatatgac tatgaaaaaa ctgttaatta tcattttgcc ggtccttctc
    36301 tccggctgta gcgcctttaa tcagctggtt gagcgcatgc aaaccgatac gctggaatac
    36361 cagtgtgatg aaaaaccgtt gacggtcaaa ctgaataatc cgcgccagga ggtcagtttt
    36421 gtttacgata atcaactact gcatctcaaa cagggcattt cagcctctgg cgcgcgttac
    36481 actgacggaa tctatgtttt ctggtcgaaa ggcgatgaag cgactgtcta taaacgcgac
    36541 cgcatcgtct tgaataactg tcagttacaa aatccacagc gttgagattt ttccaggggc
    36601 ggcgcacaat agcgtcaccc actgacaatc cgtaaagaaa accatgtctg ataacgacga
    36661 attgcagcaa atcgcgcatc tgcgccgtga atacaccaaa ggcgggttac gccgccgcga
    36721 tcttcccgcc gatccattaa ccctttttga acgttggctc tctcaggctt gtgaagccaa
    36781 actggcggac cctaccgcga tggtggtcgc taccgtggat gaacatggtc agccttatca
    36841 gcgcatcgtt ttactcaaac attacgacga aaaaggcatg gtgttttaca ccaacctcgg
    36901 cagccgtaaa gcacatcaaa tcgaaaataa tccgcgcgtt agcctgctgt tcccgtggca
    36961 tacccttgag cgccaggtga tggtgatcgg taaagcagaa cgactttcga ctctcgaagt
    37021 gatgaaatat tttcatagcc gcccgcgtga tagccagatt ggtgcatggg tttcgaagca
    37081 gtccagtcgc atttctgccc gcggtatcct tgaaagtaaa ttcctggagc tgaagcagaa
    37141 gtttcaacag ggcgaagtgc cattgccgag cttttggggc ggttttcgcg tcagccttga
    37201 acagattgag ttctggcagg gtggtgagca tcgcctgcat gaccgctttt tgtaccagcg
    37261 tgaaaatgat gcgtggaaga ttgatcgtct tgcaccctga aaagatgcaa aaatcttgct
    37321 ttaatcgctg gtactcctga ttctggcact ttattctatg tctctttcgc atctggcgaa
    37381 aagtcgtgta ccggcaaagg tgcagtcgtt atatacatgg agattttgat ggcaagcagt
    37441 aacttgatta aacaattgca agagcggggg ctggtagccc aggtgacgga cgaggaagcg
    37501 ttagcagagc gactggcgca aggcccgatc gcgctctatt gcggcttcga tcctaccgct
    37561 gacagcttgc atttggggca tcttgttcca ttgttatgcc tgaaacgctt ccagcaggcg
    37621 ggccacaagc cggttgcgct ggtaggcggc gcgacgggtc tgattggcga cccgagcttc
    37681 aaagctgccg agcgtaagct gaacaccgaa gaaactgttc aggagtgggt ggacaaaatc
    37741 cgtaagcagg ttgccccgtt cctcgatttc gactgtggag aaaactctgc tatcgcggcg
    37801 aacaactatg actggttcgg caatatgaat gtgctgacct tcctgcgcga tattggcaaa
    37861 cacttctccg ttaaccagat gatcaacaaa gaagcggtta agcagcgtct caaccgtgaa
    37921 gatcagggga tttcgttcac tgagttttcc tacaacctgt tgcagggtta tgacttcgcc
    37981 tgtctgaaca aacagtacgg tgtggtgctg caaattggtg gttctgacca gtggggtaac
    38041 atcacttctg gtatcgacct gacccgtcgt ctgcatcaga atcaggtgtt tggcctgacc
    38101 gttccgctga tcactaaagc agatggcacc aaatttggta aaactgaagg cggcgcagtc
    38161 tggttggatc cgaagaaaac cagcccgtac aaattctacc agttctggat caacactgcg
    38221 gatgccgacg tttaccgctt cctgaagttc ttcaccttta tgagcattga agagatcaac
    38281 gccctggaag aagaagataa aaacagcggt aaagcaccgc gcgcccagta tgtactggcg
    38341 gagcaggtga ctcgtctggt tcacggtgaa gaaggtttac aggcggcaaa acgtattacc
    38401 gaatgcctgt tcagcggttc tttgagtgcg ctgagtgaag cggacttcga acagctggcg
    38461 caggacggcg taccgatggt tgagatggaa aagggcgcag acctgatgca ggcactggtc
    38521 gattctgaac tgcaaccttc ccgtggtcag gcacgtaaaa ctatcgcctc caatgccatc
    38581 accattaacg gtgaaaaaca gtccgatcct gaatacttct ttaaagaaga agatcgtctg
    38641 tttggtcgtt ttaccttact gcgtcgcggt aaaaagaatt actgtctgat ttgctggaaa
    38701 taatgcatta agtggaaagg gggagtgaga aatcactccc cctggttttt atacagggaa
    38761 catgatgaaa aatattctcg ctatccagtc tcacgttgtt tatggtcatg cgggtaacag
    38821 tgcggcagag tttccgatgc gccgcctggg cgcgaacgtc tggccgctga acaccgttca
    38881 attttctaat cacacccaat acggcaaatg gactggctgc gtgatgccgc ccagccattt
    38941 aaccgaaatt gtgcaaggca ttgccgccat tgataaatta cacacctgtg atgccgtatt
    39001 aagtggctat ctgggatcgg cggagcaggg tgaacatatc ctcggtatcg tccgtcaggt
    39061 gaaagccgcg aatccgcagg cgaaatattt ttgcgatccg gtaatgggtc atccggaaaa
    39121 aggctgtatc gttgcaccgg gtgtcgcaga gtttcatgtg cggcacggtt tgcctgccag
    39181 cgatatcatt gcgccaaatc tggttgagct ggaaatactc tgtgagcatg cggtaaataa
    39241 cgtcgaagaa gcggttctgg cagcgcgcga actcattgcg caagggccac aaattgtgtt
    39301 ggttaaacac ctggcgcgag ctggctacag ccgtgaccgt tttgaaatgc tgctggtcac
    39361 cgccgatgaa gcctggcata tcagccgtcc gctggtggat tttggtatgc gccagccggt
    39421 aggtgttggt gatgtgacga gcggtttact gctggtgaaa ctgcttcagg gggcaacgct
    39481 gcaggaggcg ctggaacatg tgaccgctgc agtctacgaa atcatggtga ccaccaaagc
    39541 aatgcaggaa tatgagctgc aagtggtggc tgctcaggat cgtattgcca aaccagaaca
    39601 ttacttcagc gcaacaaagc tctgaaatat ctcatttcgg cccacaacga cctgtgggcc
    39661 gatggctatt actttaagcc ttccgctgac agcgcgtctt gtacttccgg acgttcagcc
    39721 atacgttgca taaatgctgc aatgtgctct aacccttcca gattcagttt caccgcgtat
    39781 gcccagcgca gaaccgtaaa cagacaggca tcagcaattg taaatctttg cccgcagatc
    39841 cagtgctcat ccttcagtgc ctcgttcaca tattgcagct tcttctccag ctgcgcgcga
    39901 actgtcggtt tgtactcttc cggtgtatca gggcgaaaca gaggtgtgaa acctttatgc
    39961 agctcggtgg cgatgtaatt cagccattcg atggttttat agcgggaaat actgtttacc
    40021 ggtgccagca actggcggtc ggggacgctg tcggcaagat actgcataat cgctacgcct
    40081 tccgtcagca aagtaccgtc atccagcagc aatgcaggca cctgcccctt agggttaacg
    40141 gcaaagtaat cgtcaccgtt ttcgagacgt tttttcatta aatccacact gacgagggta
    40201 aaatcctttc cgctctcacg cagggtgata tgggaagcga gagagcaggc acccggtttg
    40261 tagaacaatt tcatcggtaa ctccttttgt ctgtggttta aagtatggta gtgcgttgct
    40321 gaacaaaaaa aaagccgcta acgaaaagtt agcggcttgt aaaagagttt ccctgaattt
    40381 tacgctacgg ctgctttcgc cgctttgtct gcagcgtcat cctgcgtcat gcggtgcagt
    40441 ttcggcgcgg tcagcagcat cagtactgca ataacggcag tagcgacacc aatctgcaag
    40501 aatacgcgac catagacttc cagtgacatc agcggatcgg taacgttatc cggcacagcc
    40561 atcatacccg caacataacc accaatcagg tttgcaccgg cagtggtcag gaaccagcta
    40621 cccataatga agcccatcag acgctgcgga acgagttgag caaccattgc cagacccaga
    40681 ccagagatca tcagttcccc gatgctctgc aggccatagc ttgcgaccag ccagcttaca
    40741 gacacgatac cagcgtcaga cgcgaatttc gcacccagcg gcagaatcag gaacgcacca
    40801 gaacacatca ccatgccgat tgcaaacttg gttggcatcg gcagggtatc gcccatcttg
    40861 ttatagatag cggccagaat cggactaccg atgatgatcc agaacgggtt cagtgcctga
    40921 tactgctcag gttctacggc cagacccaga atggagtgct caacgttacg aatcgcaaag
    40981 aagttcagtg acgttggcat ctggctgtac agcacgaaga agataatggc ttcgagcatc
    41041 aggatgaagg caacgatcat tttacgacgc gcagcacctt tcatcgcgaa ggcttcttta
    41101 ccgaagataa ccacgatacc gaaggcaaca acgcccagcg ccatacgcgc aacttcctga
    41161 ttgtgcagca gccaggtggc gatagcgatc agtgccacaa caccaataat ggtcagcagc
    41221 aggttacggt agttgatagg ctcgaagtct ggttttgaac cgtactgttt aacccagcgt
    41281 tggcagaagg cgaagttaac gatagtgatc agcaggccta caacgctcaa cgcaaacgca
    41341 acactccagc cgtatttcgc ggccagccac ggcgtagcaa tcatagagaa gaaagagccg
    41401 atgttgacgg acatgtagta catggtgaat gcaccgtcca gacgcgggtc gtttttctca
    41461 tagcatgtag aaagcagaga agacgggtta gctttaaaca ggccgttacc gaccgcaata
    41521 gccgccatac ccatataaac gataccggcg tcgtgaccag accaggcaac cagagcataa
    41581 ccaatcgcca gcacaatagc gccgagcata attacgcgtt tagtacccag taccttgtca
    41641 cctaaccagc cgccgatagc gaccagacca taaaccaggg cactaaagga agagaaaagg
    41701 gtgattgaat ccgcttcaga catacccagt tgtttaacca ggtaaacagc cataattcct
    41761 tgtaggccgt aataaccaaa acgttcccat aactcaatcg agaagatgag atagaacgcc
    41821 ttcggttgtt tgaaagcgtt caaactgacg ctttcagttg gtttttggtt tgcagtggac
    41881 acttttacct ctttttttac atcccatatt aacgggggtg ctttctcgcg ttatgtataa
    41941 aaaacatacg cgcaattgtt atagtgggag gggaaacggc aggtaatgtt cactatcttg
    42001 cactttcaga caagtccttt gtaataatct gttacatata actgaggcgg ggaattcaac
    42061 cattccggga aatgttatcc agcgttaaat ttttcaaaaa acgtaacggc agattttttc
    42121 actgcactga gaggggggtg atggcttaac ggcgatatgt tctgctattt agcgttttta
    42181 ctagtgagat agtccagttt ctgaaaaata gccagtgtaa tgttttgtag gtcaatattt
    42241 gttgcgtgtg taaatttaaa tgattttaac ctgattcttg caatgttttt acattgcgac
    42301 agcatcgtga tcttgatcac gaatgaatag aaaatttcgc tattaaaaaa acaattaacc
    42361 tgcatttttg gttatccgca aacggattac ctgatgataa cgctaagcaa tggcatcatt
    42421 gacgttaaaa agatgtttta aaagaggata aagaaaggtt atcaatgggg taatcggtgt
    42481 tacccctttt cttcagatgt caactttctc tttgtattca caaagatctt caataataca
    42541 agagccacag cggggcttgc gggcaatgca ggtataacgc ccgtgcagga tcaaccaatg
    42601 gtggcagtcg actttaaact ctgctggaac cactttcagt agcttttctt ctacctgttc
    42661 gacgtttttc cccggcgcaa attgagtacg attacaaacg cggaaaatgt gcgtgtcgac
    42721 agcaatagtc ggccagccga atgcagtgtt taatacgacg ttggctgttt tacgacctac
    42781 gccgggcagg gcttcaagcg cagcacgatc ttccggaacc tcgccattat gctgctccag
    42841 caagatacgg caggttttga tgatattttc tgctttgctg ttataaagcc caatcgtttt
    42901 gatataggtt ttcacccctt caacgcccag ttcaagcatc gctgcaggcg tattcgccac
    42961 cgggtagagt ttcgccgtcg ccttattaac actgacatcg gtcgcctgag cggaaagcag
    43021 tacggcaatc agcaattcaa aaggcgaact gaaattaagc tcggtggtgg gatgaggatt
    43081 gttctcacgc aggcgagtga ggatctccag gcgttttgct ttattcatca gacattccct
    43141 gtttcaccgt ttggcaatgc acgttctgca gctgcttcag cacggcgctt tttcattctt
    43201 tcatcaatca ggtattttcc tgccagcatc agtcccaggc caataaatgc acctggtggc
    43261 agcatcgcca gcaggaaagg ggagtcggtg tggaaaatct ccacgcgtaa tacttttgcc
    43321 cagctaccta acagcgcatc tgcaccgtca aacaatgtgc cattgccgat aatttcgcgt
    43381 agtgaaccca gcacgaacat ggcgcaggtt gcgcccatac caattgaaaa gccgtccagt
    43441 gccgaaagcg ccggaccttt tttggcggcg aaggcttcag cgcggcccac aacgatacag
    43501 ttagtgacaa tcagcggaat aaaaatccct aatgattgat acaggccaaa ggcgtaggcg
    43561 ttgatcagca tctgtacagc gctgaccacc gaggcgatga tcatcacgta aatgggaatg
    43621 cggatctcgg ctggcgtcca gtgacgcagc gtcgaaatgg tcaggttggt cagcgtcagt
    43681 accagcgtag tcgcaagtcc taaacccaga gcgttagtgg cagtggacgt gaccgccaac
    43741 agaggacaaa ggccgagcaa ctggaccagc gcagagttgt ttttccacaa cccctgaaca
    43801 ataacgtctt taatttcgct cacgctttat tctccacagg caggaagttg agaaagttgt
    43861 gccggtaacg tctgagcgta caatccggcg cgttttaccg cattaaccac cgcgcgggga
    43921 gtaatcgtcg cgccggtgaa ctggtcgaaa tcaccaccat ctttcttcac cgcccagtgc
    43981 gcatcatctg caccactgat ttttttaccc gcaaaatggg tgatccagtc agaaaggcgc
    44041 agttcgattt tatcgccaag ccctggcgtt tcgtggtgct ctgtcacgcg cgtgccaagt
    44101 accgtgccgt taaaatcggc tcccaccagc agctgaatcg caccggaata gccatctggc
    44161 gcggttgctt ccagaacggc ggctaccggt ttgtcatcct gtttggcgat gtaaacccga
    44221 tgctcacctt tacctaactc tggcgcagtt accagatagc aactctgtgc cagcgcattg
    44281 ttatagcgtt cggctggcag cacctgatca aataacgcct tttgttgcag actggcctgt
    44341 tcagcaatcg tcgttttggt catctggttg atggccgcag ttaaccctgt tgaacccgct
    44401 gcaaatagcg ccaacgtaat gccgtgtttt cggatagttt tcagcatggt ttaccctttg
    44461 cgatggccgt agacgcgcgg acgcgtgtag taatcgatca gaggaaccgt gatgttcgcc
    44521 agcaggacgg caaaagccac gccgtcagga tagccgccga aactgcggat caaccagact
    44581 aataagcccg caagcgcgcc gaaaataaga cgaccacgat tggtcgtaga agcggtaacc
    44641 gggtcagtca aaataaagaa tgcgccgagc atggtcgctc cagacagcag atgaatttgc
    44701 ggtgctgcca gtgtttctgg tgagaacaac cagcccaaca ttgcgcataa cgccagcgtt
    44761 actaagaagc tgaggggaat atgccagcga atcgctttct gccatagcaa ccatacgccg
    44821 ccagccagcc aggcgagatt tacccattgc caaccagcgc ccgccagaat accgctgtag
    44881 atcggatatt gcataatctg ttcaaccgaa tgaccggcac ggacagaggt tttaaatgta
    44941 tccagcggtg tcgcctgact aatgccatca atacctaagc gtagtgtgtt catatcacca
    45001 ccactggcgg tatgaccgct aaaaataacc tggatggcgt cgataaaacc agggatgttg
    45061 accgcaattt catgtggcgg taaccagctg gtcatctgca cggggaagga gatcagtaag
    45121 accacataac caatcattgc cggattaaac gggttttgtc ccagaccgcc atacaactgt
    45181 ttagcgatga tcaccgcaaa caccgtaccc agcacgacca tccaccatgg cgcgaggggg
    45241 ggaatactta ccgccagcaa taagcctgtc agcaatgctg agttatcttt caacgttgcg
    45301 gctaccgact gcttgcgtag tttgagtacg agagcttcgg ctaacagagc actaaccgat
    45361 gccaacagga tctgaacgag agtaccccaa ccaaaaaacc acagttgcgc tgcgattcct
    45421 ggcacggctg cgagcaacac caacagcata atgcgcgatg tctggcgctg gttatgggta
    45481 taaggggagc tagctattct gaataccatt tagtcctcgt ttacaacctt ctgctgggcg
    45541 gcttttttgg cctgagcgcg ggcaatagcc gcggcaactg ccgctttgcg cggatcaacc
    45601 tgttcttctg gtaccgcatt agcctgttgc tgttccagct tgcgtgcttt ggcgcgtgca
    45661 atagccgctt cgacggcagc tttgcgcgga tcaacctgtt cttctggctc cgcattagcc
    45721 ggttgctgtt cccgtttgcg cgctttggct cgggcaatag cggcttcgac ggcggctttg
    45781 cgcggatcga cctgttgttc tggctcggca ttagcctgtt gctgttccag cttgcgtgct
    45841 ttggcacggg caatagcggc ttcgacggcg gctttgcgcg gatcgacctg ttcttctggt
    45901 tccgcattag cctgttgctg ttccagcttg cgcgctttgg cacgggcaat agcggcttcg
    45961 acggcggctt tgcgcggatc gacctgttgt tctggttccg cattagcctg ttgctgttcc
    46021 agcttgcgcg ctttggcgcg ggcgatagct gcttcaacgg cagttttacg tggatcagca
    46081 acggttgctg cgtcgttagt ttgctgcagt tctgcctgtt tcgctctggc ttgcgcttta
    46141 cgggcttccc gtgctgcaat aattgcactg ttatccgggc gttcgcccgc tttaatcaca
    46201 ataggctgtg tagcctgggc ctgtttctct ttcacccgcg ccagagcggc agcaatcgca
    46261 tctttatctt tggctgcagg ttgaacggct gcgctcttat gtcgttcaag gcgagccgct
    46321 ttttcgcgct ccagacgagc ctggcgcgct tcgaaacgcg ctttggcttc tgcggcgcgc
    46381 ttttcttcct gacgaatagc cgcaatttca gctttttcct gacggaaata ttgcaccagg
    46441 ggaatattgc tcgggcaaac ccacgcgcaa gccccacatt caatgcaatc agcaatgtta
    46501 tgcgtggtag ctttatcgtg ttgctgacct ttgctgaacc agaacaactg ttgcggcaaa
    46561 agatccgcag ggcaggcgtc agcacaggcg ctacaccgga tgcagctttg ttcttcctgt
    46621 ggttcgccaa gttcattggc agagggagcc aacagacagt tggtaatctt tacgaccggg
    46681 acatccagcc atggcaaggt aaagcccatt agcgggccac ccataatcac catttgatcg
    46741 gcagaggggc agaatccggc atcattcaat aaatgacgca ctggcgtccc cagccgtgcc
    46801 cagacgttgc ccgggcgagc gattgcttcg ccagtcaggg ttacaacacg ctcggtaatc
    46861 ggctcgccat caataacggc acgtttcact gcataagcag tgccgacgtt ttgcattaat
    46921 acgccgatat cggatgaacg cccgccatgt ggaacctgct tcccggtcag aatgtaggtt
    46981 aattgtttag caccgccaga aggatatttg gttggaatca cccgcagaga aatatcgtta
    47041 gagtccgcca gcaccgcgcg cagcatggaa atcgcctgcg gtttgttatc ttcaatgccg
    47101 ataagaattt cgcgtggctg cagaatatgc gcaagaatgc gaataccctc tacgacctga
    47161 gccgcgcaat cctgcatcaa acggtcatcg gcggtaatgt acggctcgca ctcagccgcg
    47221 ttgataatca acgtttcaat cttatctccg ccaccctgca atttaacgcc tgtcgggaat
    47281 cctgcaccgc ccagcccggc aacaccaaac tgatgtatgc gctcgattaa ctcttcgcga
    47341 ctgcgagtgc gataatcggc ccagccgtcg cgcgggatcc agcagtcttc accatcggca
    47401 tcaataatca cgcttaattc agctaaagct gaaggatgag ccgtagagtg gggcgcaata
    47461 gccgtaacgg tacccgaggt gggcgcgtga acaggcagca ttttgccgcg accacgggta
    47521 agcggctggc cgcgcaatac tttatcgccg acgctaacgc acaactcacc ttcagcgcca
    47581 atatgctgtt tcagtggaat aacaaaacgc tgcgccaggg gtacctggcg caggggtgta
    47641 ccgttggact gggttttcat ctccggtgga tggatgccgc cgttgaaatc ccagatttta
    47701 ttttttctga atgcagagaa taacttaagc atggtgttcc acgggaatga tacgcacggg
    47761 aatggtgttc agatcccatt tccaggagtc aggtgtttct gcgaccggtt gcaacgagat
    47821 gcagtgcgtc gggcacggat caacacataa attgcagccc gtacagagat cactcattac
    47881 cgtatgcatg gcacgggtag cgccaacgat ggcgtctacc ggacacgcct gaatacattt
    47941 agtgcagcca atacagttat tttcatcaat aaccgccacc atccgcgcag gcgttatctc
    48001 ttgcgcttcg ccatccagcg gctgcggctc gacattaagc aactcggcaa tttttagcat
    48061 cacagcttcg ccacctgggg cgcaacggtt gattttttca ccgttacagc tgatggcttc
    48121 cgcgtagggg cgacagccgg gataaccgca ctgaccacac tggctctgcg gtaagatttc
    48181 gtcaattttc tcaacgaccg gatcgtcttc caccgcaaaa cggcgggagg cataacccag
    48241 aatggcgcca aacgccaggc ccagcaggct cacggcggca acggcaatcc agatagcatt
    48301 cattacaact tcaccaaacc actaaagccc ataaaggcca gagacataag acctgcggta
    48361 attaacgcaa tggcattacc gcgaaaaggt gccgggacat cagccacagc aaggcgttcg
    48421 cggatggcgg cgaagagcac catcaccagc gagaaaccga cagcggcgga aaaaccgtac
    48481 agcgccgact gcaagaaatt gtgcccgaga ttgatattca gcaacgccac gccgagcact
    48541 gcacagttgg tggtgataag cggcaaaaaa atccccagca gacggtaaag caccgggctg
    48601 gttttgcgca ccaccatctc ggtgaactgc acgaccacag caatcaccag aataaatgcc
    48661 agggtgcgca ggtaaatcag attaagtggg atcaaaatcc acgtatcgat aagccaggcg
    48721 caaatagacg ccagcgtcat cacaaacgtt gttgccagcc ccatgcccat cgcggtttcc
    48781 agttttttgg aaacccccat aaacggacag agaccgagaa acttgaccag tacaaagtta
    48841 ttgaccagta cagttccgac aaacagtaac aggtagtcag tcatttttcg gcctgaaata
    48901 aaaaagccgc ctattatccg ttaatccaga gcaggcgaca acaggttaac tgtaaggtta
    48961 ttacggattc acaaacgtcg cttttacccg cgacgagcgt ttgaaatagg ggacgatcaa
    49021 tgcggttgcc aacaaagtaa acagcaactg gcgaacggct atgccatctt ccacgggtga
    49081 aaaagcgaat gcttttactg ccagcaatac ggaaataagc agccagataa tatagtgttt
    49141 aggaacacaa cgccgacgtt taaagaaagc gatggtcaac cacagtgtgt aataccacaa
    49201 ggcgatagcg gtaataaaag aaacgcccca taagatttgt gtcgtcagtg cttgtccgcc
    49261 gagcgtttga aatgtttgcg gagaagataa cgcagcggta tacagcaaca acgccagcgt
    49321 cgtactcaac agagcgacta aaagccaggc caacgggcca agcaaccagc ctccaatacg
    49381 ttgtggcgtt gtggtggtca taggttctcc agaatagcga cgcaaacagg caaatctaat
    49441 tttaggggcg ttattataag gcttttataa ccgatcgcta ctttctttat tggacatagt
    49501 gccagacgga cttcggtacc tggccgaggt caaacaaacg cccgccagaa accagctctg
    49561 cgcgacggtg atcggcagca cgatacatat tgatcagttc ctgatcgtcc gtcagggtgt
    49621 aattaagatg gtcgtagagt ttttccagac tttcgagtga actgattttg cgaaatttta
    49681 ataagtagtc ctgaacagtc ataaaaggtc cataaaataa ttaataccaa aggggtaggt
    49741 attattagtg atgataaaat ttcaccaaaa gtgaacgctt gtgttattac aataataaga
    49801 atgcgctgat ggcaaatatt cagggatgaa aaactgctct gaaaagagta acgcgcttta
    49861 ctatccctga caatcaccaa caacatcgaa caagataata aattcctggt ttaatatccg
    49921 acaagtgaaa acatgcaccc ggacgggcag catgtcgctc cacaagtgca gagcttactt
    49981 gtgttgtacc gaagcactct gttcaggtgg ctgatagttg tcaatgtgac tcgccacgcc
    50041 aagaagaatg actgaaacga caagaacgat ccaacctgtt aattcaataa gacgattcat
    50101 tacagcccac atctctcttg attgatccat taacttcagg gggtaaatgt tacttagcaa
    50161 taatagctcc agcaagattt ttactgaggt ttttgcgata tttagctttt gtcgttggaa
    50221 aattcgctat ttttttgact taagttaaac aacatccctt attgctggca ggttattaaa
    50281 ctgttgagcg tgggtaaagg atagtgtcaa atagccatca tacttcaatg agaggcaatg
    50341 acatgagcga caacatccgt gttgggttga ttgggtatgg ttatgcgagc aaaaccttcc
    50401 atgcgcccct gattgcgggc acgcccgggc tggaactggc ggtaatctcc agcagtgatg
    50461 aaacaaaagt aaaagccgac tggccaacgg ttacggttgt ctctgagccg aagcatctgt
    50521 ttaacgatcc caacatagac ctgattgtca ttcctacacc caacgatacc catttcccgt
    50581 tagccaaagc ggcgcttgag gcgggtaaac atgtggtcgt tgataaaccc tttaccgtga
    50641 cactgtcaca agcgcgagag ctggatgcgc tggcaaaaag cctggggcgt gtgctgtctg
    50701 tattccataa ccgtcgctgg gatagcgatt tcttgacgct aaaaggttta ctcgcggaag
    50761 gcgtgctggg tgaagttgct tactttgagt ctcattttga ccgcttccgt ccgcaggtgc
    50821 gcgatcgttg gcgtgaacag ggcggcccag gcagcggtat ctggtacgat ttagcaccac
    50881 atcttcttga tcaggccatt acgctttttg gtttaccggt cagcatgacg gtagatttgg
    50941 cacagttacg gcccggagcg cagtcgaccg attatttcca cgccatcttg tcctatccac
    51001 agcggcgagt cattttacac ggtaccatgc tggcagccgc tgagtcagca cggtatatcg
    51061 tgcatggatc ccgaggcagt tatgtgaaat atggcctcga tccacaggaa gaacgtctga
    51121 aaaatggcga gcgtctaccg caggaagact ggggctacga tatgcgtgat ggcgtactta
    51181 cccgcgtgga aggtgaggaa cgtgtcgaag aaacgctgtt gacggtgcct gggaattatc
    51241 cggcttacta tgcggctatt cgtgatgcgt taaatggcga tggtgaaaat ccggttccgg
    51301 caagccaggc aatccaggta atggagttga ttgagctggg catcgaatcc gccaaacatc
    51361 gcgcgacttt gtgccttgca tgaaaaatgg atggtgcatt tgcaccatcc attttgttac
    51421 ttcgcggcga ctttttctcg cagtgcgcgt ttttcctcag cgctgaggaa agccatttcc
    51481 agaccattaa tctgtgcctg gcggatttgc tcgcgggata acccagcagc tggcgcggca
    51541 acggtatatt cgtgaatgat atccactccc tgtacgccgg gatcgtcagt gttaatgctg
    51601 gcacgaatgc catgctcaag gaacgttttc agcggatgtg cagccagctc tgctacggtg
    51661 ctggtctgaa tattggaggt cagacaggat tcaataccaa tttgttgctc ggcgagaaaa
    51721 tccatcagcg cccgatcttc aatggctttt acgccatgtc caatacgctc cgcacccagt
    51781 tcacgaatcg cctgccagat gctttccggc ccggcagctt cgcctgcatg gacggtaata
    51841 tgccagcccg catcacgcgc gcggttgaag tgagaaagga acagacttcc cgggaaacca
    51901 agttcatcac cggctaaatc aagtgcggta atctggtcac ggtgggctaa aaaggcctcc
    51961 agctcttgct gacaggcggc ttcgccgaag gtccggctca taatgccgat aagcttcgcc
    52021 tgcacaccaa aggtgcggca accttcacgt acgccatcga tcaccgcttc gacaacaccc
    52081 gctacaggca gctgatgtgc cattgccatg tagcctggtg aaaaacgcag ctcgacatag
    52141 tgcaggccgt gacgggctgc atcttcaatg ttttcaaatg ccacgcggcg acaggcatca
    52201 agagaggcga gaactttaac gccccagtca agtttggtca gaaagctcac cagatcgggt
    52261 tcgttggcaa tgacctgaac gtggggaatc agtgtttcca gggattgtgc aggaagcgag
    52321 atattatact ggcggccaag ttcaagaatg gtctggggac gaatgttgcc atcaaggtgg
    52381 cgatggatat cagttaatgg cagggtggta tcaatcatgg tcgcactctt tttctggata
    52441 taaaagtgcg caccattata aaaacaaagc agggtaaaaa tccacgattg cgcaacgatt
    52501 ttttacgttg cgcaattggg gttaacgaac agcgcggatg gcgttaatta atccagccac
    52561 acctttttcc agtttcgaac gtgggcagcc ggcattgaga cggacaaaac cacgaccttc
    52621 ttcaccgtag gtataccccg gcatgatcgc gactttttct tgttcgataa gtgctttttg
    52681 caacgcgttg tcgtcaatat tcaacggacg taaatcaagc catgccagat aagtggattg
    52741 tgggatctgc cagttgagtt caggaaacgc ggcgttcatt ttatctgcga tatacgtcag
    52801 gttatctttc agatagatgc gtaaggcatc cagccacggc gcgccttgct gataggcggc
    52861 gatatgggca gttaacgcca gtaccgaagg ggaagaaagc ccatcacggc ctttcagtgc
    52921 cgataaatag gcatcgcggc tactgctatt ttctataatc ccgtaagcac cggtcagggc
    52981 gggaatattg aaacttttcg agcccgacgt tagcaacgcc cagtctccgc gagccacatt
    53041 actccaggga atatgcggct gctcgcccca aaccatatcc atatggattt catcggaaat
    53101 aacccgcaca ccatgacgct cgcacaggtc agccatgatc tccagctcat cgcacgtcca
    53161 cactttcccg gtaggattct gtgggctaca caggagcata attttacatt ctggtttcgc
    53221 caacacggct tccaacttgc ccatatcgca aaaccaacca tcagcctgct tctctaaagc
    53281 aacgggcatt actgtgcgct ggttaccttc aatggccttg taaaatgcgt cataggcggg
    53341 tgtgtggatc accacgcctt cacctgtttc agaccactga cgaatcagtt ctgaaaccat
    53401 atagatgaca gaagggccat acaccaccgt ctgagaatcg atggcggtgt aatgctgggt
    53461 ggaaaaccag tgggcaatag ccgcgagaaa ctcatcgttt ttccagcggc tgtagccaaa
    53521 tacgccgtgc atcaggcgct gattcagcgc ctcgataatg cagggggcag tggcaaaatc
    53581 catgtctgaa atcgtgaacg gtaacaggtc agcagtgccg aaacggtcag cgacataatc
    53641 ccactgtgta caccatgtgc catgacgatc cacgaccttt gaaaaatcga acatatctta
    53701 tccttatgcc tggacagtat gcatcagacc ggccatttca tcttttactg actgaacttg
    53761 tggcccgata acaacctgca ggttatgttg attaagttgt actacgccaa ttgcccgatt
    53821 gtccttcagt gcctgcacat taacaagcga catatctttc acagacaaac gcagacgggt
    53881 aatgcagtta tcgaggctga caatattgtc ggcaccgcct aatgcttcga ggattgcagg
    53941 aacgttgtaa cctgatttac ccggcgcacc ggcaacggct ttttcgattg agctggcaac
    54001 ttcgctatcg cgccccgggg ttttcagatt gaagcgggtg atagcgaaac ggaagatgac
    54061 gtagtaaacg acaaaccaga ttgccgccac cactggcacc atgtaccact tggttgacag
    54121 accatgcaaa ataccgaaca ccacgaagtc gatgatattg ccgtcggtat taccgatggt
    54181 gacgccgagc acagacatga cggtgaagcc gaggccggtt aacagcgcgt ggatgacata
    54241 cagaactggc gctacgaaca ggaacaggaa ttccagcggt tcggtagtgc cgccaacgac
    54301 gcaggcgatc aggccagaaa tcagcagacc tttaatttta tggcgatttt ccgggcgcgc
    54361 gcagtgatac atagctaacg ctgcacctgg cagaccgccg agaaacgcag gcattttacc
    54421 ttgcgaaagg aaacgcgtgg cgctttcaga aaaaccgtga gtggtcgggc aactcaattg
    54481 cgcctggaag atggtcagtg cgccgctgac ggtttgaccg cagacttcct gcgtgccgcc
    54541 tgcgtcggta aagcgaatta atgccaccag aatgtgatgc agaccaaacg gcaacagcag
    54601 acgttcaccg gtaccaaaca gcatcggtcc gaaatcaccc gcgctgttta tcatatggcc
    54661 caagccgcta atacccatgg cgaaaatcgg ccagactaat ggaatcacca ggccgacaag
    54721 gcccatcacc agcgaggaga taattggtac gaagcgcgta ccgccgaaga atgccagcgc
    54781 atccggcagg cggatattat ggaaacgctc atgcagcatc cagacgataa taccggcgat
    54841 caccgcaccg aggatcccgg tatcgatcga ctggatccca agaatgctct ggatgttatt
    54901 ggctttcaga accgcggcat ccgtggttgg cagaatgcct ttattggtca accagaagtt
    54961 taccgcgagg ttcattaccg cataaccgat gaagccagcg aatgccgcta cgcctttatt
    55021 ttcgcgtgcc aggcccagcg ggatggcgat acagaacatg acaggcagga aactaaaagc
    55081 aaacgagcca atcttactca tccaggtaaa gatagcctgc aacacggggt tgcccaggac
    55141 cgggatcagg gttatgacat catggctgct aagagaacta ccaatgccga gcataatgcc
    55201 gcagaacgac aataatgcca cgggtaacat gaaggttttg cctaactgct ggaagaactc
    55261 ccacagcgtg actttcggtg ctgttttcgc cgtcataaaa cgactcctcg tagagaacaa
    55321 tctggattca gtaaattgcg cgagaagata aaacgtttta tcaaatttta gtgaggcata
    55381 aatcacatta cgcaacgata atagcgggta taagataaat aaaaggtaaa acgttttatc
    55441 tgtcacataa tcagggagta ggtcatctgc atggctaccg ccaaaaaaat aaccattcat
    55501 gatgttgcgc tggctgcggg cgtgtcggta agtaccgttt cgctggtgct tagtggcaaa
    55561 gggcgaatct ctaccgccac aggagaacgc gttaacgccg ccattgaaga gctgggattt
    55621 gtgcgcaatc gccaggcgtc ggcgctgcgc ggcgggcaaa gcggcgtcat tggtttgatc
    55681 gtccgtgatt tatctgcgcc gttttacgcc gaattgacgg ccggattgac ggaagctctg
    55741 gaagcgcagg gacggatggt ttttttgctt cacggcggta aagacggtga gcagctggca
    55801 cagcggtttt cactgttact gaatcagggt gtcgatggtg tggtaattgc cggagctgca
    55861 ggaagtagcg atgacctgcg acggatggca gaagaaaaag ctatcccggt gattttcgct
    55921 tcccgtgcca gttatcttga tgatgttgat acggttcgcc cggacaacat gcaggctgca
    55981 cagttgttga cggagcatct cattcgcaat gggcatcagc ggatcgcctg gctgggaggg
    56041 caaagttcct cattaacccg tgcagaacgg gttgggggct attgtgcaac tctactaaaa
    56101 tttggcctgc cgtttcatag cgattgggtg ttggagtgca cttccagcca gaagcaagcc
    56161 gcggaagcta tcacggcgct tttacgtcat aacccgacca tcagtgccgt ggtttgctat
    56221 aacgaaacta ttgcgatggg ggcatggttt ggtttgctca aagcagggcg gcaaagcggg
    56281 gaaagcggag tcgatcgtta ctttgagcaa caggtttcgc tggcggcatt taccgatgcg
    56341 acaccaacca cacttgatga tatacctgtt acctgggcca gcacgccagc gcgggaactt
    56401 ggtatcacac ttgcggatcg catgatgcaa aaaatcaccc atgaagagac gcattcacgc
    56461 aatcttatta ttcccgcccg gctcattgca gcgaaataat cctctcttta tctgctatac
    56521 ctggtagtgt cctttcctca aggttaatga taaaaaatgt ggcacacagg cggtgccttt
    56581 tatttttact gaagttcaca ggaggtttat gtgtttaatt ctgacaacct gagactcgac
    56641 ggaaaatgcg ccatcatcac aggtgcgggt gcaggtattg gtaaagaaat cgccattaca
    56701 ttcgcgacag ctggcgcatc tgtggtggtc agtgatatta acgccgacgc agctaaccat
    56761 gttgtagacg aaattcaaca actgggtggt caggcatttg cctgccgttg tgatattact
    56821 tccgaacagg aactctctgc actggcagac tttgctatca gtaagctggg taaagttgat
    56881 attctggtta acaacgccgg tggcggtgga cctaaaccgt ttgatatgcc aatggcggat
    56941 tttcgccgtg cttatgaact gaatgtgttt tcttttttcc atctgtcaca acttgttgcg
    57001 ccagaaatgg aaaaaaatgg cggtggcgtt attctgacca tcacttctat ggcggcagaa
    57061 aataaaaata taaacatgac ttcctatgca tcatctaaag ctgcggccag tcatctggtc
    57121 agaaatatgg cgtttgacct gggtgaaaaa aatattcggg taaatggcat tgcgccgggg
    57181 gcaatattaa ccgatgccct gaaatccgtt attacaccag aaattgaaca aaaaatgtta
    57241 cagcacacgc cgatcagacg tctgggccaa ccgcaagata ttgctaacgc agcgctgttc
    57301 ctttgctcgc ctgctgcgag ctgggtaagc ggacaaattc tcaccgtctc cggtggtggg
    57361 gtacaggagc tcaattaata cactaacgga ccggtaaaca accgtgcgtg ttgtttaccg
    57421 ggataaactc atcaacgtct ctgctaaata actggcagcc aaatcacggc tattggttaa
    57481 ccaatttcag agtgaaaagt atacgaatag agtgtgcctt cgcactattc aacagcaatg
    57541 ataggcgctc acctgacaac gcggtaaact agttattcac gctaactata atggtttaat
    57601 gatggataac atgcagactg aagcacaacc gacacggacc cggatcctca atgctgccag
    57661 agagattttt tcagaaaatg gatttcacag tgcctcgatg aaagccatct gtaaatcttg
    57721 cgccattagt cccgggacgc tctatcacca tttcatctcc aaagaagcct tgattcaggc
    57781 gattatctta caggaccagg agagggcgct ggcccgtttc cgggaaccga ttgaagggat
    57841 tcatttcgtt gactatatgg tcgagtccat tgtctctctc acccatgaag cctttggaca
    57901 acgggcgctg gtggttgaaa ttatggcgga agggatgcgt aacccacagg tcgccgccat
    57961 gcttaaaaat aagcatatga cgatcacgga atttgttgcc cagcggatgc gtgatgccca
    58021 gcaaaaaggc gagataagcc cagacatcaa cacggcaatg acttcacgtt tactgctgga
    58081 tctgacctac ggtgtactgg ccgatatcga agcggaagac ctggcgcgtg aagcgtcgtt
    58141 tgctcaggga ttacgcgcga tgattggcgg tatcttaacc gcatcctgat tctctctctt
    58201 tttcggcggg ctggtgataa ctgtgcccgc gtttcatatc gtaatttctc tgtgcaaaaa
    58261 ttatccttcc cggcttcgga gaattccccc caaaatattc actgtagcca tatgtcatga
    58321 gagtttatcg ttcccaatac gctcgaacga acgttcggtt gcttatttta tggcttctgt
    58381 caacgctgtt ttaaagatta atgcgatcta tatcacgctg tgggtattgc agtttttggt
    58441 tttttgatcg cggtgtcagt tctttttatt tccatttctc ttccatgggt ttctcacaga
    58501 taactgtgtg caacacagaa ttggttaact aatcagatta aaggttgacc agtattatta
    58561 tcttaatgag gagtccctta tgttacgtcc tgtagaaacc ccaacccgtg aaatcaaaaa
    58621 actcgacggc ctgtgggcat tcagtctgga tcgcgaaaac tgtggaattg atcagcgttg
    58681 gtgggaaagc gcgttacaag aaagccgggc aattgctgtg ccaggcagtt ttaacgatca
    58741 gttcgccgat gcagatattc gtaattatgc gggcaacgtc tggtatcagc gcgaagtctt
    58801 tataccgaaa ggttgggcag gccagcgtat cgtgctgcgt ttcgatgcgg tcactcatta
    58861 cggcaaagtg tgggtcaata atcaggaagt gatggagcat cagggcggct atacgccatt
    58921 tgaagccgat gtcacgccgt atgttattgc cgggaaaagt gtacgtatca ccgtttgtgt
    58981 gaacaacgaa ctgaactggc agactatccc gccgggaatg gtgattaccg acgaaaacgg
    59041 caagaaaaag cagtcttact tccatgattt ctttaactat gccgggatcc atcgcagcgt
    59101 aatgctctac accacgccga acacctgggt ggacgatatc accgtggtga cgcatgtcgc
    59161 gcaagactgt aaccacgcgt ctgttgactg gcaggtggtg gccaatggtg atgtcagcgt
    59221 tgaactgcgt gatgcggatc aacaggtggt tgcaactgga caaggcacta gcgggacttt
    59281 gcaagtggtg aatccgcacc tctggcaacc gggtgaaggt tatctctatg aactgtgcgt
    59341 cacagccaaa agccagacag agtgtgatat ctacccgctt cgcgtcggca tccggtcagt
    59401 ggcagtgaag ggcgaacagt tcctgattaa ccacaaaccg ttctacttta ctggctttgg
    59461 tcgtcatgaa gatgcggact tgcgtggcaa aggattcgat aacgtgctga tggtgcacga
    59521 ccacgcatta atggactgga ttggggccaa ctcctaccgt acctcgcatt acccttacgc
    59581 tgaagagatg ctcgactggg cagatgaaca tggcatcgtg gtgattgatg aaactgctgc
    59641 tgtcggcttt aacctctctt taggcattgg tttcgaagcg ggcaacaagc cgaaagaact
    59701 gtacagcgaa gaggcagtca acggggaaac tcagcaagcg cacttacagg cgattaaaga
    59761 gctgatagcg cgtgacaaaa accacccaag cgtggtgatg tggagtattg ccaacgaacc
    59821 ggatacccgt ccgcaaggtg cacgggaata tttcgcgcca ctggcggaag caacgcgtaa
    59881 actcgacccg acgcgtccga tcacctgcgt caatgtaatg ttctgcgacg ctcacaccga
    59941 taccatcagc gatctctttg atgtgctgtg cctgaaccgt tattacggat ggtatgtcca
    60001 aagcggcgat ttggaaacgg cagagaaggt actggaaaaa gaacttctgg cctggcagga
    60061 gaaactgcat cagccgatta tcatcaccga atacggcgtg gatacgttag ccgggctgca
    60121 ctcaatgtac accgacatgt ggagtgaaga gtatcagtgt gcatggctgg atatgtatca
    60181 ccgcgtcttt gatcgcgtca gcgccgtcgt cggtgaacag gtatggaatt tcgccgattt
    60241 tgcgacctcg caaggcatat tgcgcgttgg cggtaacaag aaagggatct tcactcgcga
    60301 ccgcaaaccg aagtcggcgg cttttctgct gcaaaaacgc tggactggca tgaacttcgg
    60361 tgaaaaaccg cagcagggag gcaaacaatg aatcaacaac tctcctggcg caccatcgtc
    60421 ggctacagcc tcggtgacgt cgccaataac ttcgccttcg caatgggggc gctcttcctg
    60481 ttgagttact acaccgacgt cgctggcgtc ggtgccgctg cggcgggcac catgctgtta
    60541 ctggtgcggg tattcgatgc cttcgccgac gtctttgccg gacgagtggt ggacagtgtg
    60601 aatacccgct ggggaaaatt ccgcccgttt ttactcttcg gtactgcgcc gttaatgatc
    60661 ttcagcgtgc tggtattctg ggtgccgacc gactggagcc atggtagcaa agtggtgtat
    60721 gcatatttga cctacatggg cctcgggctt tgctacagcc tggtgaatat tccttatggt
    60781 tcacttgcta ccgcgatgac ccaacaacca caatcccgcg cccgtctggg cgcggctcgt
    60841 gggattgccg cttcattgac ctttgtctgc ctggcatttc tgataggacc gagcattaag
    60901 aactccagcc cggaagagat ggtgtcggta taccatttct ggacaattgt gctggcgatt
    60961 gccggaatgg tgctttactt catctgcttc aaatcgacgc gtgagaatgt ggtacgtatc
    61021 gttgcgcagc cgtcattgaa tatcagtctg caaaccctga aacggaatcg cccgctgttt
    61081 atgttgtgca tcggtgcgct gtgtgtgctg atttcgacct ttgcggtcag cgcctcgtcg
    61141 ttgttctacg tgcgctatgt gttaaatgat accgggctgt tcactgtgct ggtactggtg
    61201 caaaacctgg ttggtactgt ggcatcggca ccgctggtgc cggggatggt cgcgaggatc
    61261 ggtaaaaaga ataccttcct gattggcgct ttgctgggaa cctgcggtta tctgctgttc
    61321 ttctgggttt ccgtctggtc actgccggtg gcgttggttg cgttggccat cgcttcaatt
    61381 ggtcagggcg ttaccatgac cgtgatgtgg gcgctggaag ctgataccgt agaatacggt
    61441 gaatacctga ccggcgtgcg aattgaaggg ctcacctatt cactattctc atttacccgt
    61501 aaatgcggtc aggcaatcgg aggttcaatt cctgccttta ttttggggtt aagcggatat
    61561 atcgccaatc aggtgcaaac gccggaagtt attatgggca tccgcacatc aattgcctta
    61621 gtaccttgcg gatttatgct actggcattc gttattatct ggttttatcc gctcacggat
    61681 aaaaaattca aagaaatcgt ggttgaaatt gataatcgta aaaaagtgca gcagcaatta
    61741 atcagcgata tcactaatta atattcaata aaaataatca gaacatcaaa ggtgcaacta
    61801 tgagaaaaat agtggccatg gccgttattt gcctgacggc tgcctctggc cttacctctg
    61861 cttatgcggc gcaactggct gacgatgaag cgggactacg catcagactg aaaaacgaat
    61921 tgcgcagggc ggataagccc agtgctggcg cgggaagaga tatttacgca tgggtacagg
    61981 gaggattgct cgatttcaat agtggttatt attccaatat tattggcgtt gaaggcgggg
    62041 cgtattatgt ttataaatta ggtgctcgtg ctgatatgag tacccggtgg tatcttgatg
    62101 gtgataaaag ttttggcttt gccctggggg cagtaaaaat aaaacccagt gaaaatagcc
    62161 tgcttaaatt aggtcgcttc gggacggatt atagttatgg tagcttacct tatcgtattc
    62221 cgttaatggc tggcagttcg caacgtacat taccgacagt ttctgaagga gcattaggtt
    62281 attgggcttt aacaccaaat attgatctgt ggggaatgtg gcgttcacga gtatttttat
    62341 ggactgattc aacaaccggt attcgtgatg aaggggtgta taacagccag acgggaaaat
    62401 acgataaaca tcgcgcacgt tcttttttag ccgccagttg gcatgatgat accagtcgct
    62461 attctctggg ggcatcggta cagaaagatg tttccaatca gatacaaagt attctcgaga
    62521 aaagcatacc gctcgacccg aattatacgt tgaaagggga gttgctcggc ttttacgcgc
    62581 agctcgaagg tttaagtcgt aataccagcc agcccaatga aacggcgttg gttagtggac
    62641 aattgacctg gaatgcgccg tggggaagtg tatttggcag tggtggttat ttgcgccatg
    62701 caatgaatgg tgccgtggtg gataccgaca ttggctatcc cttttcatta agtcttgatc
    62761 gtaaccgtga aggaatgcag tcctggcaat tgggcgtcaa ctatcgttta acgccgcaat
    62821 ttacgctgac atttgcaccg attgtgactc gcggctatga atccagtaaa cgagatgtgc
    62881 ggattgaagg cacgggtatc ttaggtggta tgaactatcg ggtcagcgaa gggccgttac
    62941 aagggatgaa tttctttctt gctgccgata aagggcggga aaagcgcgat ggcagtacgc
    63001 tgggcgatcg cctgaattac tgggatgtga aaatgagtat tcagtatgac tttatgctga
    63061 agtaaaaaat aacgccggag agaaaaatct ccggcgtttc agattgttga caaagtgcgc
    63121 gttttttatg ccggatgcgg cgtaaacgcc ttatccagcc tacaaaaact cataaattca
    63181 aagtgttgca ggaaaaggta ggcctgataa gcgtagcgca tcaggcaatc tctggtttgt
    63241 tttcagatga aaacgccgga gtgaaaattc tccggcgttt tggccgtgaa ttactgctgc
    63301 ggaattgccg gtacagccgg aacgttaaga gctggcatcg caaacatgcc aacaaaatct
    63361 tctaacgaca ttttctgccc atttaacgtt atctgaccgt tagcatattg caggctggtg
    63421 gtgatggtat tgtcctgcaa ggtggtcaga cggaacatct gccccattgc tgatgcacct
    63481 tcaacttgct gtttcgccag ttttttcgct tgatcttcct gataaccttc cagcttcgct
    63541 acctgagtca taaactcagt tgccatatcc accggaatgg tcagtttcgc atccagagat
    63601 ttaaccgaac gatctacttc ctgcgccagc gtttgcggcg cttctttagt cgttgccgga
    63661 tctttcagga acagcgacag attcagggca ctttcaccct gactgttttt ccagcttagc
    63721 ggcgcgatag taatcaccgg atcgcctttc agcatcagcg gcagggcgct aaagaaggct
    63781 tccgtcactt tctcctgata aagttcgggg ttgttggcaa tttctggctg tgccagcagc
    63841 gcctgagttt gcgcgttata ttgctggcta aactgatgcc aggcttcacc atcaatctgg
    63901 ccgactttta aagtcagctt gccgctgccc agatcctgat tctgtacctt caggctgttt
    63961 agcgagtaat ccagttggct attgatcgtt ttaccgtcat tgaccagatc cgatttaccg
    64021 ctgatctcca tgccttccag cagtgccagt tctttgcctt ccactgaaat ggtcattttt
    64081 tccagtgaca gtttttgatt tcctacacgc tcaccaaaac ttgccagcgt gctggaaccg
    64141 tcggttttca gattattaaa ggtcaactgc actttctggt tgtattcgtt aactgcgtct
    64201 atccgaccac tttgcgcctc cccggaaagg gagatggctt tgccgtctct gtcagcattt
    64261 aactggaact cgccgccgct aaaggcgact ttttcatctt tttgctcgta attcagtggc
    64321 ttgagcgaaa tatcggaact ggaatcaccg ctgtaaccaa tgcgcgagtt aatctcaaaa
    64381 ggcgtttcac cttttgccat atcaaacagt ggtttgctta cttcgttatt aaccagcgtg
    64441 gtttgaattg atgccatcga cgggatcagg ttcagttttt taagctgggc aagcgggaag
    64501 ggaccatgat caaccgattc gttgaagatg acgctctgac cgcttttaat ccacggattt
    64561 tctttcccgg caatgggttt caccaacagt tgcaactggc tgctgaatac gccgcgatga
    64621 tagttttgat aactcacttc caggttggat tcaggagctg tcagtttgag ttgcgcgttc
    64681 gcctgcgcga ccatgtcttc gagatgggtt tcaatcttct tgcctgtata ccatgcgccg
    64741 cctgtccaga ctacgcctag cgcaacaatg acgcctaccg ctaccagcga tttattcata
    64801 atgattatcc ataaaatgaa atcaggcgga ctggccgcct gaaggtgtta taagccttta
    64861 ataagcttag caagagatgt taattttttc agtaagctct tacagcttgt tgtaaacacg
    64921 cgctaaacgg ccgtggcctt tgacagtcac cggtgattcg ttggcggcaa taaacgctga
    64981 ttcacccggt ttaagctgta actgctgaga acctttccac aacgttgcat cgccttcgac
    65041 gcagaacaaa atggcggcac tctgctggct aatggtggtt tctttatcac taaggtcatg
    65101 cagcgagaag gcaaaatcat ccactggaat cgggaagtcc agttctgcac cttgtttcac
    65161 cggctgggtc aacaactggt tagccggttt ggcttcgaat ttcacattgg caaccagttc
    65221 cggaatatca atgtatttag gcgtcagacc cgcacgcagc acgttatcgg agtttgccat
    65281 cacttccagc gccacgcctt gcaggtaagc gtgcggtgtt tcagcgaaca ggaacatcgc
    65341 ttcgccaggg ttcaatttca ccacattcag caatagcggg gagaacagac cgctgtcttc
    65401 cgggtaaaat tcagaaatta aacgaatcgt ttgccacggt tcaccctgct ggctatcgag
    65461 ggccgatttt aaaatcgcca gcgcgcggga tttttcttca ccctgcatat tcaacaggct
    65521 ggcgaacagt tcgcttaaac gttcggcatc aggctgttgt aaaaagtgag caatcgccgg
    65581 atgtgcacct gcgaccggct ggagtaggga gacaatctcg gaaaattcac gaaacgcgtt
    65641 catcgcaagg aaaggcgtca gcgcaaaaac cagctccggc ttgtggttag gatctttata
    65701 gttacgctcg gcggcatcca tcgggatacc tgcggcattt tctttggcaa aaccgatttc
    65761 agaattgtgt ttgtttggat gaacctgaat ggagagtggc tgtgctgcgc ataatacttt
    65821 gaacaggaaa ggcagttcgc caaagcgttt ggcaacggcc tctccgagca gagtcgattt
    65881 atcactctca atcacatcac gcagtgaaac gatatctccg gcggcattct gcactcgtga
    65941 actgcttttc ggatgtgcgc ccatccacag ctcggccatc ggctggctgg acggattttc
    66001 cataccataa agttcagtca acgccgtttt gctgccccag gcatagtttt gcactgagtt
    66061 aatgagtttt tgcatgatca atccctgttt taatgtggaa attaatccca ctattaaagc
    66121 aagaatccta cgggaagtaa cctggagccg caaaaagtcg tactagtctc agtttttgtt
    66181 aaaaaagtgt gtaggatatt gttactcgct tttaacaggg caacggaaca cccgcccaga
    66241 gcataaccaa accaggcagt aagtgagaga acaatgtcaa acaaaccctt tcattatcag
    66301 gctccttttc cactcaaaaa agatgatact gagtattacc tgctaaccag cgaacacgtt
    66361 agcgtatctg aatttgaagg gcaggagatt ttgaaagtcg cacccgaagc gttaactctg
    66421 ttggcgcgcc aggcgtttca tgatgcgtcg ttcatgctgc gtccggcgca ccaacaacag
    66481 gtggccgaca ttctgcgtga cccggaggcc agcgaaaatg ataaatatgt ggcgctgcaa
    66541 ttcctgcgta actccgacat cgcggcgaaa ggcgttctgc caacctgtca ggataccggc
    66601 accgcgatta ttgttggtaa aaaagggcag cgtgtatgga ccggtggtgg tgatgaagcg
    66661 gcgctggcgc gcggtgtcta taacacttat atcgaagata atctgcgcta ctcgcaaaac
    66721 gcgccgctgg atatgtataa agaagtgaat accggcacca atctgccagc gcagatcgat
    66781 ctttatgccg ttgatggcga cgaatacaaa ttcctctgta tcgccaaagg tggtggttcg
    66841 gcaaacaaga cgtatctcta tcaggaaacc aaagcgttac tgacgccggg gaaactgaaa
    66901 aattacctgg ttgagaagat gcgcacgctg ggtacggcgg cctgtcctcc gtatcatatt
    66961 gcgttcgtta ttggtggaac ttctgcagaa acgaacctta aaacggtgaa actggcttcc
    67021 gcgaaatact atgatgaact gccaacggaa gggaatgagc acggtcaggc gttccgcgat
    67081 gtggaactgg aaaaagaatt gctgatcgaa gcgcaaaatc ttggtctggg tgcgcagttt
    67141 ggtggtaaat acttcgctca cgacatccgc gtgattcgcc tgccacgtca cggcgcatcc
    67201 tgcccggtcg gtatgggcgt ctcctgctct gctgaccgta atatcaaagc gaagatcaac
    67261 cgtcagggga tctggatcga aaaactggaa cataatccag gcaaatatat cccggaagag
    67321 ctgcgcaaag cgggagaagg cgaagcggtg cgcgttgacc ttaaccgtcc gatgaaagag
    67381 atcctcgcac agttgtcgca gtatcccgtt tctacacgct tatcgcttaa cggcacgatt
    67441 atcgtcggtc gtgatattgc tcacgccaaa ctgaaagagc ggatggataa cggtgaaggg
    67501 ctgccgcagt acatcaaaga tcatccgatt tactacgcgg gtccggccaa aacgccggaa
    67561 ggttatgcct ccggttctct tggcccaacg accgccggac ggatggattc ttatgtcgat
    67621 caactgcaag cgcagggcgg aagtatgatc atgctggcga aaggcaaccg cagccagcag
    67681 gtgacggatg cctgtaaaaa acacggcggc ttctaccttg gcagtatcgg tggtccggcc
    67741 gctgtattgg cgcagggaag tattaagagc ctggaatgtg ttgaatatcc ggaactggga
    67801 atggaagcca tctggaaaat tgaagtggaa gatttcccgg cgtttatcct tgtggatgat
    67861 aaaggaaatg acttcttcca gcagatacaa ctcacacaat gcacccgctg tgtgaaataa
    67921 acagagccgc ccttcggggc ggttttttta catggcacga aagaccaaac atttgttatc
    67981 aaatggtaaa taataagtga gctaaaagtt gcttaacgaa agcaaaacag aaagaaaaaa
    68041 ttaatcaggt gaggagcagg tcatgaatac agtacgcagc gaaaaagatt cgatgggggc
    68101 gattgatgtc ccggcagata agctgtgggg cgcacaaact caacgctcgc tggagcattt
    68161 ccgcatttcg acggagaaaa tgcccacctc actgattcat gcgctggcgc taaccaagcg
    68221 tgcagcggca aaagttaatg aagatttagg cttgttgtct gaagagaaag cgagcgccat
    68281 tcgtcaggcg gcggatgaag tactggcagg acagcatgac gacgaattcc cgctggctat
    68341 ctggcagacc ggctccggca cgcaaagtaa catgaacatg aacgaagtgc tggctaaccg
    68401 ggccagtgaa ttactcggcg gtgtgcgcgg gatggaacgt aaagttcacc ctaacgacga
    68461 cgtgaacaaa agccaaagtt ccaacgatgt ctttccgacg gcgatgcacg ttgcggcgct
    68521 gctggcgctg cgcaagcaac tcattcctca gcttaaaacc ctgacacaga cactgaatga
    68581 gaaatcccgt gcttttgccg atatcgtcaa aattggtcgt actcacttgc aggatgccac
    68641 gccgttaacg ctggggcagg agatttccgg ctgggtagcg atgctcgagc ataatctcaa
    68701 acatatcgaa tacagcctgc ctcacgtagc ggaactggct cttggcggta cagcggtggg
    68761 tactggacta aatacccatc cggagtatgc gcgtcgcgta gcagatgaac tggcagtcat
    68821 tacctgtgca ccgtttgtta ccgcgccgaa caaatttgaa gcgctggcga cctgtgatgc
    68881 cctggttcag gcgcacggcg cgttgaaagg gttggctgcg tcactgatga aaatcgccaa
    68941 tgatgtccgc tggctggcct ctggcccgcg ctgcggaatt ggtgaaatct caatcccgga
    69001 aaatgagccg ggcagctcaa tcatgccggg gaaagtgaac ccaacacagt gtgaggcatt
    69061 aaccatgctc tgctgtcagg tgatggggaa cgacgtggcg atcaacatgg ggggcgcttc
    69121 cggtaacttt gaactgaacg tcttccgtcc aatggtgatc cacaatttcc tgcaatcggt
    69181 gcgcttgctg gcagatggca tggaaagttt taacaaacac tgcgcagtgg gtattgaacc
    69241 gaatcgtgag cgaatcaatc aattactcaa tgaatcgctg atgctggtga ctgcgcttaa
    69301 cacccacatt ggttatgaca aagccgccga gatcgccaaa aaagcgcata aagaagggct
    69361 gaccttaaaa gctgcggccc ttgcgctggg gtatcttagc gaagccgagt ttgacagctg
    69421 ggtacggcca gaacagatgg tcggcagtat gaaagccggg cgttaatctg caacatacag
    69481 gtgcagccgt ggaatgatca aacgaagcgg ctgcgcctga ggtttataac ggtgctgcac
    69541 attgtcggca tcgtaattta acaactcacc aacgtccggc acgcccgcgc cattatcccg
    69601 attaatcagt gcaatcagtg gtgtagggca ggcgtgttgg acttgttttt gatctccttt
    69661 gtaccagacg cgggcaatcg gctgcacctt caccggacgt ttgattttta acttcgcgtt
    69721 ctgtggcagg gcagcgatat cctgatactc tcgctccagt tttctttgcc actcctcgcg
    69781 cgtccacggt gcgacactgc gtggtgattt caggcttttt tccagctgtg ccaggacttc
    69841 atcacgatgt aaattcttaa tgatatgttt attagcccaa ccaaagcgta aagtggcggg
    69901 gtcgtgcaga acggtgagcg tgcggtaagc attaagggtg atcagccccg gcaaatgacg
    69961 atgcacccat tcaaaacgtg ccgcggtggg gagttctgat tcaaccgtga cgatatgctc
    70021 gaacgtggtc ttgagtttat tgatgtgctg aatatgactg accaacgctg cttgcgaaag
    70081 gttatcgacc tggtaacaca acacgccagg cagacggaca gcggccttgc tgctgcgatt
    70141 ttcggactgt tgttgaataa ataaatggcg gaaatgacgc aacgccagcg actgcgcgtc
    70201 gttgccgaga tgttgtttta cctcaatacg attaagcgga ttatgctcat cctctttttt
    70261 tacctccggc aaagagaaca cgcgggcaac caatagcttg tgttgctcaa gatgagcggc
    70321 aaatatagcc agctcttgtt ccatctggcg aaaggtagtg ttgagtcggt ctacgagatc
    70381 gtaacgcgcc ataatattaa ccactttagt tacaacatac ttattttata gcacagtcgt
    70441 ggtgacttga ccatcgtgcg cgtagtgtca ggcagaggta aattgcggga tgttatgcca
    70501 taacggccag ctaaacgaga agcgggcacc acccagttcg ctggtgtcac aattaaccgt
    70561 accgcccatt gccagtgcta tagagtggac aattgccagc cccagcccgc agccgccggt
    70621 tgagcgatcc cggctgggat cgaggcgaac aaaaggttca aagatatgtt cgcggttttc
    70681 tggggcaatc cctgggccat catcctcaac aattaatgtc gctctattcc ccgacagtag
    70741 caggctggtt tcaaccgttg aatggcagta ccgcagggcg ttattgagca aattatccag
    70801 cacgcgctcc attaagcgca tatccaacgc cgcataatgg ccttgcacga gcgtttttat
    70861 ccgtaccgtt ttatcgggcg ttactgcctg aatatctgcc agatgcgttg acagccacaa
    70921 cggcaggtct ggttcgctaa gatgaagctc gttttgtggg cgatcgagtc gggcataagt
    70981 cagcagctct tcaattaaag cttcaagttg actgatatca cgattcaacg cctgggattc
    71041 ggcggcgctc aggttatcgc tcatctccag tcgataacgc aggcgcacta acggtgttcg
    71101 cagttcgtga gcgataccgt caataagctg ttttttgctg gcaattaagg cgttgatatt
    71161 gtccgccatc tggttaaatg cgacgccaag tcgttcaaag ctcgaaccct catcaaagtg
    71221 gatacgttca ttgagatgcc catcgccaaa tcgttgcgcc gctgcttcca gttttaacat
    71281 atcctgccag tgcggacgca tccagataaa caccggaaag gcgagggaaa tagcaataaa
    71341 agcgatcagg gcgatatcca gcaatcgcat ctgatggaga taataaagat aaggaacagg
    71401 accaactgcc agcacgtagt ggctgcgcgg gatacgctgc aaaaacgtgt actgatcgtc
    71461 cagggcgaca atttcgccgc cacgcagtcg gtgcatggaa atatcatcaa gatggtattt
    71521 actcagtggc tcgacacgca gatcgaaaga gagatttaaa tccatctctt tcagagtttt
    71581 accccagtcg tgtgggggga tctcacgcaa ttcgctgcgc atcagataca gcgaactgtt
    71641 catcaaatca tccagcgact gtttgcccgc gcgttcggcg gtaaatttgt acaccagccc
    71701 aaccagcaga gacatcacaa ggaagcagac aaacaataac aggtaaaact ggataaacag
    71761 ttttttcatc gcttattccc atgcatgagg cgcaaaaaga tagcctttgt tacgcacagt
    71821 tttaatgcga taaggttctg cggcgttatc gagcagtttt tttcttaacc gcgaaatagc
    71881 cacgtccacg ctacgatcca gtccgtcata actgacgccg cgtaaatttt tcagcaatgc
    71941 atcgcggtcc atgatttgcc cggcatgggt agctaattcc cacaataatt cgaaatcagc
    72001 tgtcgagagc gagatttcag tgttagccag ggtgactacg cggttgatgg gatcgatggt
    72061 caacgtgccg aaatgcaggg ctttgtaggg agtcagagac gtttcctgaa gacctttggt
    72121 cagtgtggct tgctcattct gacgcaaatg caaacgtaaa cgcgctagca aaacagcagg
    72181 gggcgtcgtt ttgagaatat agtcgcaggc acccatttcc agtgccagga tgtggttcat
    72241 atcgctatcg agagaggtta gaagaacaat cggtccagac cactttgcgc gtaaatcacg
    72301 acaaatggtc atgccgtcct tgcctggtag catgatgtcg agtaacacca aatccggatt
    72361 ttctcgcaaa atggtttctt cggcctggtc gccgcgcggc tctacggtaa cctgcatatc
    72421 atgttttgcc aggtacgcgg caatcagtga accgacttcc gcatcatctt ccacaaatac
    72481 gatagtgttc ataacattca cggtagatat aaaaacgtca caatacaccg cgctgttttt
    72541 acttactatc aatcgtttct aaacaagttt tcatcaggta ttctactgat gacttgttat
    72601 ggaagtgtta aggtaaaaag atggggctgg taatcaaagc cgcgctcggt gcgctggtag
    72661 tgctgttgat tggtgtttta gcaaaaacga aaaattatta tatcgccggg ctgattccac
    72721 ttttcccgac ctttgcgctt atcgcgcatt atattgttgc cagcgaacgc ggcattgaag
    72781 ccttacgcgc aaccatcatt tttagtatgt ggtcgattat tccctatttt gtttacctgg
    72841 tgtcgctgtg gtatttcacc ggaatgatgc gcttgcccgc cgcttttgtt ggttctgttg
    72901 cgtgttgggg gataagcgca tgggtgttga ttatatgctg gataaagctg cattaacgca
    72961 gatgacgacc gccatcaagt gggaaactgc gtccggtgac aaagcaactg gtaagtaagt
    73021 aatcgaccag gtcgatcact tctttctcgc caggcgcggt tttcatcagt gatttattca
    73081 gcgcctgttg tcgatattcg gcatcatcat gttcattaaa caggatcagc gatggcgcaa
    73141 tagaattcac tttcacttcc ggtgccagct tgcgggcaaa cgagcgggtc atattatcca
    73201 gtgccgcttt gcttgcagca tacgcaatat gtttgtcgct accgcgctcc accacataat
    73261 cggtaaagtg aatgatatcg ctggcggcgt gtccgtgccc acgcagtaat ctttccagcg
    73321 catggttgag caggtatggg gtattaacgt ggatctgcat catgcaagcc agtacgtcgg
    73381 ccagtggcgc acccggtttt tccgccatcc acgcactggc gttatgcaaa atagcacgca
    73441 gaccatgggt gctttttagt acttcatcgg caaacgccat cacaccgtcg ttggtcgaaa
    73501 aatcagcctg aatacactgc gcacctgcat taatcagtcc atcaatggct ggatagtgtg
    73561 tccgatagct gacaatcacc ggttgctttt gattaatgaa atgccatgcg agggcgaggc
    73621 cgatgcgacg acctccgcca gtaattaata ttggcaaggg ctgggtttta cccatcgtta
    73681 tctcctttgc tatccaacga tgggatgaac gttatcccac cagcatccag gtcgccggaa
    73741 ctgaggcaat taacagcatg ccaatcagca ccatttcctg acggttcagt acattatcat
    73801 gggtatgcgt tttgcgcgcg tacaggaaaa ccagcagccc cggtgcatac agaacaacgg
    73861 ataacagcaa gtgcattgga ccagaggcgt acaataacca taagccataa atgcaggcac
    73921 cgacacctac cgctttatgc agtggacggg ttgcgatttt cagcaagaac gcgccgacca
    73981 ggaaataggg caccagaatc atttctgagg cgatggtcag caacgtgttg taatcggaac
    74041 cggtcagcca gatgagtacc agacaaattt gcacgcagat gttggtcaac cacagtgagg
    74101 cggatggcgc agcttgtgcg ttctggcgcg caaaaatgcg cgggaatgct ttatgagtgg
    74161 cggccaggaa cggtacttct gctgccatga tggtccagct taagtacgcg ccgcaaacgg
    74221 aaacgatcaa accggcagcg atgatgattt cgccccatgg tcccatcatt tccaccatca
    74281 gaccggccat tgacgggtta cgaatttcag ccagttcagg acgtgccacc acacccagcg
    74341 aaagcagcgt taccagcaag taaacgccca gagcggagag aaccgccagc agtgtcgctt
    74401 tgccaacatc acgtttatta cgcgcacgcg cagaaacaac cacggcacct tccacaccaa
    74461 tgaaaaccca cagggtgatc agcatggtgt ttttcacctg ttcccaaacg ggtacgccaa
    74521 gtgcaagtcc ggtgaagtcg agcttgaagg tatccagttt gaacatcatc atcgccagca
    74581 caacaaacag acccagcggc aacaattttg ccagtgtcgc caccaggtta atgctggcag
    74641 cggtttgcac cccgcgcagg atcaaaaagt gaacaatcca caataaagcc gatgcaccga
    74701 ctatcgattg ccaggtatta ccatcgccaa acaggcgcaa ttccggcgtg tccgtaaaaa
    74761 agcttaacgc ggaaaaaacg atcaccagat aggagacgtt ggcgatgact gcgcacagcc
    74821 agtatcccca tgcggaacaa aagccgatta gctcgccaaa cccttcgcgg gcataggtaa
    74881 agataccgcc gtcaagttcg ggacgaatgc gcgtgaggat cagcatggca aaggccagca
    74941 ataaaatgcc agcgccagta ataccccagc cgatgagcag tgctgccggg ctggcaactg
    75001 ccgccatatt ttgcggcaga ctgaaaacac ccgcgcccag cattgagctt aataccagcg
    75061 cggtgagtgc gctcagtccc agtttctttt ccatcgatat ccagtgatta aaacgtgata
    75121 agaagaataa atattagggc aaaacgcata aaaatggagt ttgccactga agcgcgggat
    75181 tttacgaaga gatgtgtctg catgcaatgg tcgcggggaa atttgtgact aaaaatgcga
    75241 aaggcggcat caagccgcct tataggagta actgaatagt tatttataca gatctgcgct
    75301 gacggtcagg ttattaccac gttcctgcca ctggcgggtg atgtggtaat acttagcacc
    75361 tttcttcgcg gcacgtttcg caacctgata ggagacttcg gtcatgttgc cgtagttgcc
    75421 agagaatttg atgctgtcga acgggaccat catcgctgcg gtcgctttgt tcagttcttc
    75481 gactttagtg ccatccggga gcgtgacggt gtaacgcccg ccttttgatg actgggtttc
    75541 aaagaagcga ccgacttcag aacttggtga tgcggtagtc gcaacacccg ggatctcaac
    75601 tttcttcgcg gcttcgccac cggcagccag agctgcacgt cctgcttcgg aatctgccgg
    75661 gatcacatcc gggctctgga cgatacgttt cttagcatct tttttataga tgaatgcagt
    75721 aatacgctgg ttgccgccct ggttggcatc gatttgacga acgatgtaga aagagtaggc
    75781 acctttcgct tttgccgctt tggtgatggc atcattgact tctggctggc tacgatagaa
    75841 gccctggacg gtgaccgtgt caaacggttc aatcagaaca gcctgatctt tcggcagttc
    75901 gacaacaccg ttaattacgc gattacttgt ttcttctgct ttttcagcat cggctttata
    75961 gaggtcagcg accacacgcc agttaccgct gttaccaaaa tcagaagtgt cgacaacata
    76021 aaaagaggcg gcaccttctt tatctgcgcg acgagaaacg gctttcaccg cttcgccaat
    76081 agcattaaaa cgaccggtaa ccactacacg gtcaaaaggt ttaaccgctg ccgcttgctc
    76141 cggtgtcagt tctgttgctg cgttaacgga gaatgccgta gcagaaagca gtgccgacgc
    76201 caggagggtg ttcttaagct tcataaaaat aatccttcgc cttgcgcaaa ccaggtactg
    76261 gtattgttat taacgagaaa cgtggctgat tattgcattt aaacggtgta actgtctgcg
    76321 tcatttttca tatcacattc cttaagccaa ttttaatcct gctcaaatga ccgtctatgc
    76381 ttaaaaaaca gccgtatcag catcattact actgaagcaa ctgaattgta taagttaatt
    76441 taatgttaag tagtgattcg tgccggggcg atgtctcgtt ttacccgacc gtcgaagaca
    76501 attatcagtc tttatccggc gttctaaggt gtttatccca ctatcacggc tgaatcgtta
    76561 atattttgcg agttcacgcc gaaatactga tttttggcgc tagatcacag gcataatttt
    76621 cagtacgtta tagggcgttt gttactaatt tattttaacg gagtaacatt tagctcgtac
    76681 atgagcagct tgtgtggctc ctgacacagg caaaccatca tcaataaaac cgatggaagg
    76741 gaatatcatg cgaattggca taccaagaga acggttaacc aatgaaaccc gtgttgcagc
    76801 aacgccaaaa acagtggaac agctgctgaa actgggtttt accgtcgcgg tagagagcgg
    76861 cgcgggtcaa ctggcaagtt ttgacgataa agcgtttgtg caagcgggcg ctgaaattgt
    76921 agaagggaat agcgtctggc agtcagagat cattctgaag gtcaatgcgc cgttagatga
    76981 tgaaattgcg ttactgaatc ctgggacaac gctggtgagt tttatctggc ctgcgcagaa
    77041 tccggaatta atgcaaaaac ttgcggaacg taacgtgacc gtgatggcga tggactctgt
    77101 gccgcgtatc tcacgcgcac aatcgctgga cgcactaagc tcgatggcga acatcgccgg
    77161 ttatcgcgcc attgttgaag cggcacatga atttgggcgc ttctttaccg ggcaaattac
    77221 tgcggccggg aaagtgccac cggcaaaagt gatggtgatt ggtgcgggtg ttgcaggtct
    77281 ggccgccatt ggcgcagcaa acagtctcgg cgcgattgtg cgtgcattcg acacccgccc
    77341 ggaagtgaaa gaacaagttc aaagtatggg cgcggaattc ctcgagctgg attttaaaga
    77401 ggaagctggc agcggcgatg gctatgccaa agtgatgtcg gacgcgttca tcaaagcgga
    77461 aatggaactc tttgccgccc aggcaaaaga ggtcgatatc attgtcacca ccgcgcttat
    77521 tccaggcaaa ccagcgccga agctaattac ccgtgaaatg gttgactcca tgaaggcggg
    77581 cagtgtgatt gtcgacctgg cagcccaaaa cggcggcaac tgtgaataca ccgtgccggg
    77641 tgaaatcttc actacggaaa atggtgtcaa agtgattggt tataccgatc ttccgggccg
    77701 tctgccgacg caatcctcac agctttacgg cacaaacctc gttaatctgc tgaaactgtt
    77761 gtgcaaagag aaagacggca atatcactgt tgattttgat gatgtggtga ttcgcggcgt
    77821 gaccgtgatc cgtgcgggcg aaattacctg gccggcaccg ccgattcagg tatcagctca
    77881 gccgcaggcg gcacaaaaag cggcaccgga agtgaaaact gaggaaaaat gtacctgctc
    77941 accgtggcgt aaatacgcgt tgatggcgct ggcaatcatt ctttttggct ggatggcaag
    78001 cgttgcgccg aaagaattcc ttgggcactt caccgttttc gcgctggcct gcgttgtcgg
    78061 ttattacgtg gtgtggaatg tatcgcacgc gctgcataca ccgttgatgt cggtcaccaa
    78121 cgcgatttca gggattattg ttgtcggagc actgttgcag attggccagg gcggctgggt
    78181 tagcttcctt agttttatcg cggtgcttat agccagcatt aatattttcg gtggcttcac
    78241 cgtgactcag cgcatgctga aaatgttccg caaaaattaa ggggtaacat atgtctggag
    78301 gattagttac agctgcatac attgttgccg cgatcctgtt tatcttcagt ctggccggtc
    78361 tttcgaaaca tgaaacgtct cgccagggta acaacttcgg tatcgccggg atggcgattg
    78421 cgttaatcgc aaccattttt ggaccggata cgggtaatgt tggctggatc ttgctggcga
    78481 tggtcattgg tggggcaatt ggtatccgtc tggcgaagaa agttgaaatg accgaaatgc
    78541 cagaactggt ggcgatcctg catagcttcg tgggtctggc ggcagtgctg gttggcttta
    78601 acagctatct gcatcatgac gcgggaatgg caccgattct ggtcaatatt cacctgacgg
    78661 aagtgttcct cggtatcttc atcggggcgg taacgttcac gggttcggtg gtggcgttcg
    78721 gcaaactgtg tggcaagatt tcgtctaaac cattgatgct gccaaaccgt cacaaaatga
    78781 acctggcggc tctggtcgtt tccttcctgc tgctgattgt atttgttcgc acggacagcg
    78841 tcggcctgca agtgctggca ttgctgataa tgaccgcaat tgcgctggta ttcggctggc
    78901 atttagtcgc ctccatcggt ggtgcagata tgccagtggt ggtgtcgatg ctgaactcgt
    78961 actccggctg ggcggctgcg gctgcgggct ttatgctcag caacgacctg ctgattgtga
    79021 ccggtgcgct ggtcggttct tcgggggcta tcctttctta cattatgtgt aaggcgatga
    79081 accgttcctt tatcagcgtt attgcgggtg gtttcggcac cgacggctct tctactggcg
    79141 atgatcagga agtgggtgag caccgcgaaa tcaccgcaga agagacagcg gaactgctga
    79201 aaaactccca ttcagtgatc attactccgg ggtacggcat ggcagtcgcg caggcgcaat
    79261 atcctgtcgc tgaaattact gagaaattgc gcgctcgtgg tattaatgtg cgtttcggta
    79321 tccacccggt cgcggggcgt ttgcctggac atatgaacgt attgctggct gaagcaaaag
    79381 taccgtatga catcgtgctg gaaatggacg agatcaatga tgactttgct gataccgata
    79441 ccgtactggt gattggtgct aacgatacgg ttaacccggc ggcgcaggat gatccgaaga
    79501 gtccgattgc tggtatgcct gtgctggaag tgtggaaagc gcagaacgtg attgtcttta
    79561 aacgttcgat gaacactggc tatgctggtg tgcaaaaccc gctgttcttc aaggaaaaca
    79621 cccacatgct gtttggtgac gccaaagcca gcgtggatgc aatcctgaaa gctctgtaac
    79681 cctgacggcc tctgctgagg ccgtcactct ttattgagat cgcttaacag aacggcgatg
    79741 ctttgacctc ccgctgtttg ttcaagcgca attttgacaa taattgtcaa cggcacggaa
    79801 agcagcatac ccaccggtcc taacaaccat ccccaaaaaa tcaacgacaa aaataccacc
    79861 aatgtggaaa gccccagccc acgccccatg atacgcggct ccagaatatt gccgaagacc
    79921 agattaatca gcagatatcc cgccagcacc agcaacgctt cgtagaagcc attaaacacc
    79981 agtacctgag cgataggggg gattgccgcg aggactgaac caatattcgg gatgtaatta
    80041 agcgcaaagg ccagcaatcc ccagacaaaa gcgaagcgaa catcgagtgc ggcgagcatc
    80101 gcccaggcga ccaggccggt gatgatgctg atggctgttt tcagcaccag ataatgagaa
    80161 acactgtcaa tcgcacgttg aatcgccgcc atcccttcaa ccggacgcgc catcatttgc
    80221 tgaaattttc cgggcaattg tggcacttcg agcagcataa acagcaccgt cagcagcaat
    80281 aaaaatattg atgacatggc attagataac tgcgtcaata agttggtgag caacgtcatc
    80341 gccgcgttcg gatcaatata atgcgccagc tggtcaactg agacgtcaat ccctacgcgt
    80401 tgcaacaacg gttcaagcgc ttgcagcggc gtcataatag agttgcgata ttgcggtaac
    80461 gtccgcgtca actcgttgag cgcggaaccc agataagcta atagcaacac catcgccatc
    80521 acgatgatgg tcatcaaaat cgacaccgcc agtacacgcg gcacacgcca gcggaccatg
    80581 tgttgcacca gcgggttaag aataacagca ataaataatg cgagaataaa cggcacgatg
    80641 atctcggcgg caaaacggat accgcagaga ataatgacca gcattcccaa cataatgacg
    80701 atttttaggc cattgagcgt gatgatcggc tttgccatgc ttgtccccgt tttttcttcc
    80761 tttgctaata ataatgtctt tttcgctccg tcatcataac gaaaatcaaa ccgctcaggt
    80821 aaagaagtga aaatattttg agttaattct taagctatga tacaaatcag gcgtgttcaa
    80881 ctaccgagga caattatcat ccgcgatgac gagaagcaac actgcggata attgtaatat
    80941 tatggacaat ttgttcagga cgttattttc tacatttacc catcttcgta cctcatccac
    81001 tatcttgctc gtaggtgagc agcactggcg caacgcgctt tagtcctttc ttctgccaaa
    81061 gcttgcgcta tgcgcggggc ttgaccactt tactttggtt tcgctgaatt aagcgaaaat
    81121 taaaataatt ctcttgcagg agaaggacaa tgtatattta ttggatttta ttaggtctgg
    81181 ctattgctac agaaattacc ggtacgctgt caatgaaatg ggcgagcgtc agtgagggaa
    81241 atggcggctt tattttaatg ctggtgatga tttctctgtc gtatatattt ctctctttcg
    81301 ccgttaaaaa aatcgcctta ggcgtagctt atgcgctgtg ggaaggtatc ggtattttat
    81361 ttattacctt gtttagcgtt ttgttattcg acgaaagttt atcgctgatg aaaattgccg
    81421 ggttaaccac cctggtcgcc gggattgtgt tgataaaatc aggtacccgt aaagcgcgta
    81481 aacctgaact ggaggtgaac catggcgcag tttgaatggg ttcacgccgc ctggctggca
    81541 ttggcaatcg tgctggaaat cgttgctaac gtctttttga aattttctga cggctttcgt
    81601 cgcaaaatat ttggcttgct ctccctggcg gcggtgctgg ctgcctttag tgcgctttct
    81661 caagccgtta aagggatcga cttgtctgtc gcttatgcat tgtggggcgg gtttggtatt
    81721 gccgccacgt tagccgcagg ttggatcttg tttggtcaac ggttaaatcg taaaggctgg
    81781 attggcctgg tcttgctgtt ggctggaatg atcatggtga aacttgcctg atgaagacgc
    81841 tgcccgcgct gtcgggcagc gtttgaacat tatttttgcg acagttgatc cagcttgtcg
    81901 cgaaaaccgg taacagaaat ggcccggtta tcggcgcgcc agcgatcttt cgcggcagga
    81961 gccgaacttt gcaccccaat taattgccag ccgtcatcgg tatgcaacat cagaggcgaa
    82021 ccgctgtcac ccggcaaggt atcgcactga tgtgacatca ccgacgtttg cgcccagcca
    82081 gtcacttcac agttttgatg actgtacaac gtatcgagat gatcttcagg gtagcctgcc
    82141 tgagtcactt tacgacctgc cgcttttaat gcggcggtaa gcgcggcttt atctccctca
    82201 aataacggca acggcgtaat gccagaaggg ggattacgta gcacaatcaa tccgaagtcc
    82261 cacggcgcgg ctgcgggagg tacaatccaa ccatccccat ctgcttttaa ccgctttccc
    82321 agtgtcggat caacgcggcc ttctatgtcg tggatctcat agcgccaaag acctttattt
    82381 gacacaaaac gcagcgccac tgctttatcg gctttaccct ttggaggtgt caataaacag
    82441 tgtcctgccg ttaatgccag attgggtgca atcagcgtcg ccgtacataa attgccgctg
    82501 gccgtttcca gttgcccaac cgcatcccac ggtgattggg tcgtgtcatt cactggcaca
    82561 cgatcatcat gaccaaaaaa cagggtgctg acctcatcgt ttgccgatct ggcaacgtct
    82621 ggtttatctg caaacacaaa agcagacgtc aaactaattg cacccaacac tacagcaatg
    82681 gttgtacgca tatcacactc tggtgggtaa ttatgattat taaaagcaaa ccctcataaa
    82741 tactatagac gggacgggat gaaagtggga gtaaaatcag ataactacaa tcaggaaaga
    82801 taaaaacggg cggcaatcag tgcgcataaa ataaggatga tcagaatgaa ctcaaagcga
    82861 taacggccca ccatactacc ctccgctaaa ggcggtgcta aacgttaccc gcttagcacc
    82921 gtaattttca ggcgcgaggg ggcgcgccag cattactgtt gaaaacttac gctgcgggtt
    82981 gtgcagcagg ttttgccggt tgctgatggc tgtgtttctt ggcgtgtttc ttcgctgcct
    83041 gcgctttttg ttcaggggct ttctgttcag ctttcgtatt tttatgatgc tttttagccg
    83101 cctgcgcttt ctgggcaggt gctgctttat gctgtttttt atgatgtgta gttttcgccg
    83161 gcgctgcttt ggtggtcgtc gcagtcggag caggtgtggt cgtagtctct gcagcaaagg
    83221 cggcagaaga cagacccata gcagcggcaa caaccagagc taatactttt ttcattgtca
    83281 taccctcaat ttgttttttc atttaacccc actgcggggc cgttgaaata actatatccc
    83341 tgggaatggc agacttccgt gagtggttgg tttcagcgtg taacgatatg tacaaacgct
    83401 gaataaatta cagcgttgat aataacgtat tgtgacttaa gggaaattta gctaccaata
    83461 atagtagtct tgatcgggtt aactatttta ctacttacaa agcagtagaa taactgcgca
    83521 tcagtaataa atgacacaca gcaaaatgaa tccgtttatt tgggtactta taatcctgat
    83581 gacgctagac gcgctgcggg aattggctgg cgcttcgtct attttaggat ggctattaac
    83641 gttggtttga gctggcaata agtccggacg ggtatttacc gcagtccgga cttatttttc
    83701 aggcgtgcag acgacgatgc aaacgcgtcc cgaccagcag agcaatgacc agcatcagag
    83761 caataaatgc gccgacgccg ttccagccat agttatgcca gaaaacacca cccagcgtcc
    83821 cggcaatact cgaccccaga tagtaactga acagatacag cgaggaggcc tggcctttag
    83881 cgcgttttgc gcgggggccg atccagctgc tggctactga gtgggctgcg aagaatcctg
    83941 ctgagaagag taacattccg gcaaagatca gccacagcga gctgaataag gtcatcagta
    84001 aaccaaacag cataaccccc gtcgaaaaca acatcactgg accacgccca tagcgggtgg
    84061 tcatggttcc ggctttgggt gagctccatg taccggtcaa ataagccagc gataataagc
    84121 caaccacggc ctgactgaca tgccaggggg agagcatcaa ccgatagccg atgtaattaa
    84181 acagcgtgac gaacgacccc atcagcaaaa agccttctgc gaacaataac ggtaatcccc
    84241 ggtcacgcca gtgcagacga aagttgataa acaacgtctt agggcgcagc gaagtcgggc
    84301 gaaaatggcg tgattcaggg aggattttcc agaacatcaa cgccgaggcc agcgcgaaac
    84361 aaccgattgc cgccagagca attcgccagt tgaaaaagtc cgtgaagaca ccgctaatta
    84421 agcgtccgct catgccgcca attgagttgc cgctgatata caaccccatt gaaaaggcca
    84481 cgaaactggg atggatttcc tcgctaagat aagtcatgcc aacagctgcc acgccactta
    84541 acgaaagccc aatcaaggcg cgcataatca aaatgccgtg ccagctggtc atcattgtcg
    84601 aaagtaacgt acaaatggag gccaacagta gcgccgtgac catcactggt ttgcgaccaa
    84661 tggcatcgga tagcgggcca gtaaacagca aaccaatagc caacatcgcc gtggaaatgg
    84721 acagtgaaat actactgttc gcgggggtta agccaaactc ctgcgaaagc accggaagga
    84781 taggctgcac acaatagaga agtgcaaatg ttgccagtcc ggcagagaac agcgccaggg
    84841 tgacgcgcat aaattgcggc gtaccgcgtt taataaattg atttggctga gaaatgcttt
    84901 gcttgtcagt gtcgcttgcc ggagcgccat caacagttgt agtacggctc acttgaaatc
    84961 cttgctaaat atgcctgtag atcaggctta tacatagggt aggaaaa
//
LOCUS       DAPOAV010000006        82632 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.006, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000006 DAPOAV010000000
VERSION     DAPOAV010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 82632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 82632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..82632
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.006"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            2..169
                     /locus_tag="RN951_000525"
     CDS             2..169
                     /locus_tag="RN951_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfL family protein"
                     /protein_id="HDX2525585.1"
                     /translation="MNKFIKVALVGAVLATLTACTGHIENRDKNCSYDYLLHPAISIS
                     KIIGGCGPTAQ"
     gene            413..1801
                     /gene="frlA"
                     /locus_tag="RN951_000526"
     CDS             413..1801
                     /gene="frlA"
                     /locus_tag="RN951_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417829.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine/psicoselysine transporter"
                     /protein_id="HDX2525586.1"
                     /translation="MTANSPLQRIGQEKGIAMGSQELQRKLGFWAVLAIAVGTTVGSG
                     IFVSVGEVAKAAGTPWLTVLAFVIGGLIVIPQMCVYAELSTAYPENGADYVYLKNAGS
                     RPLAFLSGWASFWDNDAPSLSIMALAIVSNLGFLTPIDPLLGKFIAAGLIIAFMLLHL
                     RSVEGGAAFQTLITIAKIIPFTIVIGLGIFWFKAENFAAPTTTAIGATGSFMALLAGI
                     SATSWSYTGMASICYMTGEIKNPGKTMPRALIGSCLLVLVLYTLLALVISGLMPFDKL
                     ANSETPISDALTWIPALGSTAGIFVAITAMIVILGSLSSCVMYQPRLEYAMAKDNLFF
                     KCFGHVHPKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLVMCFKNTLTFGSIIWC
                     RKRDDYKPLWRTPAFGLMTTLAIASSLILVASTFVWAPIPGLICAVIVIATGLPAYAF
                     WAKRSRQLNALS"
     gene            1822..2844
                     /gene="frlB"
                     /locus_tag="RN951_000527"
     CDS             1822..2844
                     /gene="frlB"
                     /locus_tag="RN951_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417830.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-phosphate deglycase"
                     /protein_id="HDX2525587.1"
                     /translation="MLDIDKSTVDFLVTENMVQEVEKVLSHDVPLVHAIVEEMVKRDI
                     DRIYFVACGSPLNAAQTAKHLADRFSDLQVYAISGWEFCDNTPYRLDDRCAVIGVSDY
                     GKTEEVIKALELGRACGALTAAFTKRADSPITSAAEFSIDYQADCIWEIHLLLCYSVV
                     LEMITRLAPNAEIGKIKNDLKQLPNALGHLVRTWEEKGRQLGELASQWPMIYTVAAGP
                     LRPLGYKEGIVTLMEFTWTHGCVIESGEFRHGPLEIVEPGVPFLFLLGNDESRHTTER
                     AINFVKQRTDNVIVIDYAEISQGLHPWLAPFLMFVPMEWLCYYLSIYKDHNPDERRYY
                     GGLVEY"
     gene            2894..3724
                     /gene="frlC"
                     /locus_tag="RN951_000528"
     CDS             2894..3724
                     /gene="frlC"
                     /locus_tag="RN951_000528"
                     /EC_number="5.1.3.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 3-epimerase"
                     /protein_id="HDX2525588.1"
                     /translation="MKTGMFTCGHQRLPIEHAFRDASELGYDGIEIWGGRPHAFAPDL
                     KAGGIKQIKALAQTYQMPIIGYTPETNGYPYNMMLGDEHMRRESLDMIKLAMDMAKEM
                     NAGYTLISAAHAGYLTPPNVIWGRLAENLSELCEYAENIGMDLILEPLTPYESNVVCN
                     ANDVLHALALVPSPRLFSMVDICAPYVQAEPVMSYFDKLGDKLRHLHIVDSDGASDTH
                     YIPGEGKMPLRELMRDIIERGYEGYCTVELVTMYMNEPRLYARQALERFRALLPEDER
                     "
     gene            3721..4506
                     /gene="frlD"
                     /locus_tag="RN951_000529"
     CDS             3721..4506
                     /gene="frlD"
                     /locus_tag="RN951_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HDX2525589.1"
                     /translation="MKTLATIGDNCVDIYPQLNKAFSGGNAVNVAVYCTRYGIQPGCI
                     TWVGDDDYGTKLKQDLARMGVDISHVHTKHGVTAQTQVELHDNDRVFGDYTEGVMADF
                     ALSEEDYAWLAQYDIVHAAIWGHAEDAFPQLHAAGKLTAFDFSDKWDSPLWQTLVPHL
                     DFAFASAPQEDETLRLKMKAIVARGAGTVIVTLGENGSIAWDGAQFWRQAPEPVTVID
                     TMGAGDSFIAGFLCGWSAGMTLPQAIAQGTACAAKTIQYHGAW"
     gene            4606..5337
                     /gene="phoB"
                     /locus_tag="RN951_000530"
     CDS             4606..5337
                     /gene="phoB"
                     /locus_tag="RN951_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417834.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator PhoB"
                     /protein_id="HDX2525590.1"
                     /translation="MSATDRYSHQLLYATVRQRLLDDIAQGVYQAGQQIPTENELCTQ
                     YNVSRITIRKAISDLVADGVLIRWQGKGTFVQSQKVENALLTVSGFTDFGVSQGKATK
                     EKVIEQERVSAAPFCEKLNIPGNSEVFHLCRVMYLDKEPLFIDSSWIPLSRYPDFDEI
                     YVEGSSTYQLFQERFDTRVVSDKKTIDIFAATRPQAKWLKCELGEPLFRISKIAFDQN
                     DKPVHVSELFCRANRITLTIDNKRH"
     gene            complement(5489..6574)
                     /locus_tag="RN951_000531"
     CDS             complement(5489..6574)
                     /locus_tag="RN951_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDX2525591.1"
                     /translation="MKTFPLQSLTIIEAQQKQFALVDSICRHFPGSEFLTGGDLGLTP
                     GLNQPRVTQRVEQVLADAFHAQAAALVQGAGTGAIRAGLAALLKPGQRLLVHDAPVYP
                     TTRVIIEQMGLTLITVDFNDLSALKQVVDEQQPDAALVQHTRQQPQDSYVLADVLATL
                     RAAGVPALTDDNYAVMKVARIGCECGANVSTFSCFKLFGPEGVGAVVGDADVINRIRA
                     TLYSGGSQIQGAQALEVLRGLVFAPVMHAVQAGVSERLLALLNGGAVPEVKSAVIANA
                     QSKVLIVEFHQPIAARVLEEAQKRGALPYPVGAESKYEIPPLFYRLSGTFRQANPQSE
                     HCAIRINPNRSGEETVLRILRESIASI"
     gene            complement(6586..7890)
                     /locus_tag="RN951_000532"
     CDS             complement(6586..7890)
                     /locus_tag="RN951_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfT family protein"
                     /protein_id="HDX2525592.1"
                     /translation="MDLYIQIIVVACLTGMTSLLAHRSAAVFHDGIRPILPQLIEGYM
                     NRREAGSIAFGLSIGFVASVGISFTLKTGLLNAWLLFLPTDILGVLAINSLMAFGLGA
                     IWGVLILTCLLPVNQLLTALPVDVLGSLGELSSPVVSAFALFPLVAIFYQFGWKQSLI
                     AAVVVLMTRVVVVRYFPHLNPESIEIFIGMVMLLGIAITHDLRHRDENDIDASGLSVF
                     EERTSRIIKNLPYIAIVGALIAAVASMKIFAGSEVSIFTLEKAYSAGVTPEQSQTLIN
                     QAALAEFMRGLGFVPLIATTALATGVYAVAGFTFVYAVGYLSPNPMVAAVLGAVVISA
                     EVLLLRSIGKWLGRYPSVRNASDNIRNAMNMLMEVALLVGSIFAAIKMAGYTGFSIAV
                     AIYFLNESLGRPVQKMAAPVVAVMITGILLNVLYWLGLFVPA"
     gene            complement(7902..8255)
                     /locus_tag="RN951_000533"
     CDS             complement(7902..8255)
                     /locus_tag="RN951_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417837.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2620 domain-containing protein"
                     /protein_id="HDX2525593.1"
                     /translation="MKKIGVAGLQREQIKKTIEATAPGCFEVFIHNDMEAAMKVKSGQ
                     LDYYIGACNTGAGAALSIAIAVIGYNKSCTIAKPGIKAKDEHIAKMIAEGKVAFGLSV
                     EHVEHAIPMLINHLK"
     gene            complement(8266..9144)
                     /locus_tag="RN951_000534"
     CDS             complement(8266..9144)
                     /locus_tag="RN951_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotriesterase-related protein"
                     /protein_id="HDX2525594.1"
                     /translation="MSFDPTGYTLAHEHLHIDLSGFKNNVDCRLDQYAFICQEMNDLM
                     TRGVRNVIEMTNRYMGRNAQFMLDVMRETGINVVACTGYYQDAFFPEHVATRSVQELA
                     QEMVDEIEQGIDGTELKAGIIAEIGTSEGKITPLEEKVFIAAALAHNQTGRPISTHTS
                     FSTMGLEQLALLQAHGVDLSRVTVGHCDLKDNLDNILKMIDLGAYVQFDTIGKNSYYP
                     DEKRIAMLHALRDRGLLNRVMLSMDITRRSHLKANGGYGYDYLLTTFIPQLRQSGFSQ
                     ADVDVMLRENPSQFFQ"
     gene            complement(9141..10367)
                     /locus_tag="RN951_000535"
     CDS             complement(9141..10367)
                     /locus_tag="RN951_000535"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDX2525595.1"
                     /translation="MARFVVLVIDSFGVGAMKDVTLVRPQDAGANTCGHILSQLPHLQ
                     LPTLEKLGLINALGYAPGDMQPSDSATWGVAELQHEGGDTFMGHQEILGTRPLPPLRM
                     PFRDVIDRVEQALVSAGWQVERRGDDLQFLWVNQAVAIGDNLEADLGQVYNITANLSV
                     ISFDDAIKIGRIVREQVQVGRVITFGGLLTDSQRILDAAESKEGRFIGINAPRSGAYD
                     NGFQVVHMGYGVDEKVQVPQKLYEAGVPTVLVGKVADIVNNPYGVSWQNLVDSQRIMD
                     ITLNEFNTHPTAFICTNIQETDLAGHAEDVARYAERLQVVDRNLARLVEAMQPDDCLV
                     VMADHGNDPTIGHSHHTREVVPVLVYQQGMIATQLGVRTTLSDVGATVCEFFRAPPPQ
                     NGRSFLSSLRFAGDTL"
     gene            complement(10367..11530)
                     /locus_tag="RN951_000536"
     CDS             complement(10367..11530)
                     /locus_tag="RN951_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfX family PLP-dependent enzyme"
                     /protein_id="HDX2525596.1"
                     /translation="MFVEALKRQNPALISAALSLWQQGKIAPDSWVIDVDQILENGKR
                     LIETARLYGIELYLMTKQFGRNPWLAEKLLALGYSGIVAVDYKEARVMRRAGLPVAHQ
                     GHLVQIPCHQVADAVEQGTDVITVFTLDKAREVSAAAVKAGRIQSVLLKVYSDDDFLY
                     PGQESGFALKVLPEIVAEIQNLPGLHLAGLTHFPCLLWDEAVGKVLPTPNLHTLIQAR
                     DQLAKSGIALEQLNAPSATSCTSLPLLAQYGVTHAEPGHALTGTIPANQQGDQPERIA
                     MLWLSEISHHFRGDSYCYGGGYYRRGHAQHALVFTPENQKITETNLKTVDDSSIDYTL
                     PLAGEFPVSSAVVLCFRTQIFVTRSDVVLVSGIHRGEPEIVGRYDSLGNSLGA"
     gene            complement(11614..11976)
                     /locus_tag="RN951_000537"
     CDS             complement(11614..11976)
                     /locus_tag="RN951_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417841.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDX2525597.1"
                     /translation="METRLNLLCEAGVIDKDICKGMMQVVNVLETECHLPVRSEQGTM
                     AMTHMASALMRSRRGEEIEPLDNELLAELAQSSHWQAVVQLHQVLLKEFALEVNPCEE
                     GYLLANLYGLWMAANEEV"
     gene            complement(11993..12898)
                     /locus_tag="RN951_000538"
     CDS             complement(11993..12898)
                     /locus_tag="RN951_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2525598.1"
                     /translation="MRRTFIKKEGVVITTLARYLLGEKCGNRLKTIDELANECRSSVG
                     LTQAALKTLESSGAIRIERRGRNGSYLVEMDNKALLTHVDINNVVCAMPLPYTRLYEG
                     LASGLKAQFDGIPFYYAHMRGADIRVECLLNGVYDMAVVSRLAAESYLTQKGLCLALE
                     LGPHTYVGEHQLICRKGESANVKRVGLDNRSADQKIMTDVFFGGSDVERVDLSYHESL
                     QRIVKGDVDAVIWNVVAENELTMLGLEATPLTDDPRFLQATEAVVLTRVDDYPMQQLL
                     RAVVDKHALLAHQQRVVSGEQEPSY"
     gene            complement(13188..14192)
                     /gene="trpS"
                     /locus_tag="RN951_000539"
     CDS             complement(13188..14192)
                     /gene="trpS"
                     /locus_tag="RN951_000539"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HDX2525599.1"
                     /translation="MTKPIVFSGAQPSGELTIGNYMGALRQWVNMQDDYHCIYCIVDQ
                     HAITVRQDAQKLRKATLDTLALYLACGIDPEKSTIFVQSHVPEHAQLGWALNCYTYFG
                     ELSRMTQFKDKSARYAENINAGLFDYPVLMAADILLYQTNLVPVGEDQKQHLELSRDI
                     AQRFNALYGEIFKVPEPFIPKSGARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVK
                     KIKRAVTDSDEPPVVRYDVQNKAGVSNLLDILSAVTGQSIPELEKQFEGKMYGHLKGE
                     VADAVSGMLTELQERYHRFRNDEAFLQQVMKDGAEKASAHASRTLKAVYEAIGFVAKP
                     "
     gene            complement(14185..14943)
                     /gene="gph"
                     /locus_tag="RN951_000540"
     CDS             complement(14185..14943)
                     /gene="gph"
                     /locus_tag="RN951_000540"
                     /EC_number="3.1.3.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycolate phosphatase"
                     /protein_id="HDX2525600.1"
                     /translation="MNKFEDIRGVAFDLDGTLVDSAPGLAAAVDMALYALELPVAGEE
                     RVITWIGNGADVLMERALTWARQERATQRKTMGKPPVDDDIPAEEQVRILRKLFDRYY
                     GEVAEEGTFLFPHVADTLGALQAKGLPLGLVTNKPTPFVAPLLEALDIAKYFSVVIGG
                     DDVQNKKPHPDPLLLVAERMGIAPQQMLFVGDSRNDIQAAKAAGCPSVGLTYGYNYGE
                     AIDLSQPDVIYQSINDLLPALGLPHSENQESKND"
     gene            complement(14936..15613)
                     /gene="rpe"
                     /locus_tag="RN951_000541"
     CDS             complement(14936..15613)
                     /gene="rpe"
                     /locus_tag="RN951_000541"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDX2525601.1"
                     /translation="MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVP
                     NLTIGPMVLKSLRNYGITAPIDVHLMVKPVDRIVPDFAAAGASIITFHPEASEHVDRT
                     LQLIKENGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
                     VRRRIDESGFDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDQPDYKKVIDEMRSE
                     LAKVSHE"
     gene            complement(15631..16467)
                     /gene="dam"
                     /locus_tag="RN951_000542"
     CDS             complement(15631..16467)
                     /gene="dam"
                     /locus_tag="RN951_000542"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
                     /protein_id="HDX2525602.1"
                     /translation="MKKNRAFLKWAGGKYPLLDDIKRHLPKGECLVEPFVGAGSVFLN
                     TDFSRYILADINSDLISLYNIVKMRTDEYVQAARELFVPETNCAEVYYQFREEFNKSQ
                     DPFRRAVLFLYLNRYGYNGLCRYNLRGEFNVPFGRYKKPYFPEAELYHFAEKAQNAFF
                     YCESYADSMARADDASVVYCDPPYAPLSATANFTAYHTNSFTLEQQAHLAEIAEGLVE
                     RHIPVLISNHDTMLTREWYQRAKLHVVKVRRSISSNGGTRKKVDELLALYKPGVVSPA
                     KK"
     gene            complement(16574..17860)
                     /gene="damX"
                     /locus_tag="RN951_000543"
     CDS             complement(16574..17860)
                     /gene="damX"
                     /locus_tag="RN951_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DamX"
                     /protein_id="HDX2525603.1"
                     /translation="MDEFKPEDELKPDPSDRRTGRSRQSSERSERTERGEPQINFDDI
                     ELDDTDDRRPTRAQKERNEEPEIEEEIDESEDETVDEERVERRPRKRKKAASKPASRQ
                     YMMMGVGILVLLLLIIGIGSALKAPSTTSSDQTASGEKSIDLAGNATDQANGVQPAPG
                     TTSAENTQQDVSLPPISSTPTQGQTPVATDGQQRVEVQGDLNNALTQPQNQQQLNNVA
                     VNSTLPTEPATVAPVRNGNASRDTAKTQTAERPSTTRPARQQAVIEPKKPQATVKTEP
                     KPVAQTPKRTEPAAPVASTKAPAATSTPAPKETATTAPVQTASPAQTTATPAAGAKTA
                     GNVGSLKSAPSSHYTLQLSSSSNYDNLNGWAKKENLKNYVVYETTRNGQPWYVLVSGV
                     YASKEEAKKAVSTLPADVQAKNPWAKPLRQVQADLK"
     gene            complement(17952..19040)
                     /gene="aroB"
                     /locus_tag="RN951_000544"
     CDS             complement(17952..19040)
                     /gene="aroB"
                     /locus_tag="RN951_000544"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HDX2525604.1"
                     /translation="MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNET
                     LAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVAL
                     GGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
                     ASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYC
                     IRRCCELKAEVVAADERETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAA
                     RTSERLGQFSSAETQRIITLLKRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLIL
                     PLAIGKSEVRSGVSHELVLNAIADCQSA"
     gene            complement(19097..19618)
                     /gene="aroK"
                     /locus_tag="RN951_000545"
     CDS             complement(19097..19618)
                     /gene="aroK"
                     /locus_tag="RN951_000545"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004709337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroK"
                     /protein_id="HDX2525605.1"
                     /translation="MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTG
                     ADVGWVFDLEGEEGFRDREEKVINELTEKQGIVLATGGGSVKSRETRNRLSARGVVVY
                     LETTIEKQLARTQRDKKRPLLHVETPPREVLEALANERNPLYEEIADVTIRTDDQSAK
                     VVANQIIHMLESN"
     gene            complement(20019..21257)
                     /gene="hofQ"
                     /locus_tag="RN951_000546"
     CDS             complement(20019..21257)
                     /gene="hofQ"
                     /locus_tag="RN951_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA uptake porin HofQ"
                     /protein_id="HDX2525606.1"
                     /translation="MKQWIAALLLMLIPGVQAAKPQKVTLMVDDVPVAQVLQALAEQE
                     KLNLVVSPDVSGTVSLHLTDVPWKQALQTVVKSAGLITRQEGNILSVHSIAWQNNNIA
                     RQEAEQARAQANLPLENRSITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDN
                     KTALSALEQWVAQMDLPVGQVELSAHIVTINEKSLRELGVKWTLADAQHAGGVGQVTT
                     LGSDLSVATATTHVGFNIGRINGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIK
                     QGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQKGRIRLKLHISQNVPGQVLQQA
                     DGEVLAIDKQEIETQVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDG
                     KEDERRELVVFITPRLVSSE"
     gene            complement(21169..21573)
                     /gene="hofP"
                     /locus_tag="RN951_000547"
     CDS             complement(21169..21573)
                     /gene="hofP"
                     /locus_tag="RN951_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417851.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofP"
                     /protein_id="HDX2525607.1"
                     /translation="MRVKRWLLAGIALCLLTGMRDPFKPPEDLCRISELSQWRYQGMV
                     GRGERIIGVIKDGQKKWRRVQQNDVLENGWTILQLTPDVLTLGTGTNCEPPQWLWQRQ
                     GDTNEAMDSRTTVDADTRRTGGKAAKSDADGG"
     gene            complement(21563..22003)
                     /gene="hofO"
                     /locus_tag="RN951_000548"
     CDS             complement(21563..22003)
                     /gene="hofO"
                     /locus_tag="RN951_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofO"
                     /protein_id="HDX2525608.1"
                     /translation="MNMFFDWWFATSPRLRQLCWAFWLLMLVTLIFLSSTHHEERDAL
                     IRLRASHHQQWAALYRLVDTTPFSEEKTLPFSPLDFQLSGAQLVSWHPSAQGGELALK
                     TLWEAVPSAFTRLAERNVSVSRFSLSVEGDDLLFTLQLETPHEG"
     gene            complement(21987..22526)
                     /gene="hofN"
                     /locus_tag="RN951_000549"
     CDS             complement(21987..22526)
                     /gene="hofN"
                     /locus_tag="RN951_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofN"
                     /protein_id="HDX2525609.1"
                     /translation="MNPPINFLPWRQQRRTAFLRFWLLMFVAPLLLAVGITLILRLTG
                     SAEARIDAVLLQAEQQLARSLQITKPRLLEQQQLREQRSQRQRQRQFTRDWQSALEAL
                     AALLPEHAWLTTISWQQGTLEIKGLTTSITALNALETSLRQDASFHLNQRGATQQDAQ
                     GRWQFEYQLTRKVSDEHVL"
     gene            complement(22526..23305)
                     /gene="hofM"
                     /locus_tag="RN951_000550"
     CDS             complement(22526..23305)
                     /gene="hofM"
                     /locus_tag="RN951_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417854.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofM"
                     /protein_id="HDX2525610.1"
                     /translation="MAFKIWQIGLHLQQQEAVAVAIVRGAKECFLQRWWRLPLENDII
                     KDGRIVDAQQLAKTLLPWSRELPQRHHIMLAFPASRTLQRSFPRPSMSLGEREQTAWL
                     SGTMARELDMDPDSLRFDYSEDSLSPAYNVTAAQSKELATLLTLAERLRVHVSAITPD
                     ASALQRFLPFLPSHQQCLAWRDNEQWLWATRYSWGRKLAVGMTSAKELAAALSVDPES
                     VAICGEGGFDPWEAVSVRQPPLPPPGGDFAIALGLALGKAY"
     gene            23425..25977
                     /gene="mrcA"
                     /locus_tag="RN951_000551"
     CDS             23425..25977
                     /gene="mrcA"
                     /locus_tag="RN951_000551"
                     /EC_number="2.4.1.129"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417855.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase/peptidoglycan
                     DD-transpeptidase MrcA"
                     /protein_id="HDX2525611.1"
                     /translation="MKFVKYFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRL
                     QIPMQIYSADGELIAQYGEKRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIF
                     RAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEIL
                     ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRA
                     VARRNVVLSRMLDEGYITQQQFDQTRTEAINANYHAPEIAFSAPYLSEMVRQEMYNRY
                     GESAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPANVLWKVGESAWDNN
                     KITDTLKALPTYGPLLPAAVTSANPQQATAMLADGSTVALSMEGVRWARPYRSDTQQG
                     PTPRKVTDVLQTGQQIWVRQVGDAWWLAQVPEVNSALVSINPQNGAVMALVGGFDFNQ
                     SKFNRATQALRQVGSNIKPFLYTAAMDKGLTLASMLNDVPISRWDASAGSDWQPKNSP
                     PQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTESLALGSA
                     SFTPMQVARGYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKVACPECDIPVIYGDT
                     QKSNVLENNDVEDVAISREQQNVSVPMPQLEQANQALVAKTGAQEYAPHVINTPLAFL
                     IKSALNTNIFGEPGWQGTGWRAGRDLQRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVW
                     IGFDDHRRNLGHTTASGAIKDQISGYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPG
                     IVTVNIDRSTGQLANGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGEAQELF"
     gene            complement(26143..26703)
                     /gene="nudE"
                     /locus_tag="RN951_000552"
     CDS             complement(26143..26703)
                     /gene="nudE"
                     /locus_tag="RN951_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP compounds hydrolase NudE"
                     /protein_id="HDX2525612.1"
                     /translation="MSKSLQKPTILNVETVARSRLFTVESVDLEFSNGVRRVYERMRP
                     TNREAVMIVPIVDDHLILIREYAVGTESYELGFSKGLIDPGESVYEAANRELKEEVGF
                     GANDLTFLKKLSMAPSYFSSKMNIVVAQDLYPESLEGDEPEPLPQVRWPLAHMMDLLE
                     DPDFNEARNVSALFLVREWLKGQGRV"
     gene            27023..29158
                     /gene="igaA"
                     /locus_tag="RN951_000553"
     CDS             27023..29158
                     /gene="igaA"
                     /locus_tag="RN951_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular growth attenuator protein IgaA"
                     /protein_id="HDX2525613.1"
                     /translation="MSTIVIFLAALLACSLLAGWLIKVRSRRRQLPWTNAFADAQTRK
                     LTPEERSAVENYLESLTQVLQVPGPTGASAAPISLALNAESNNVMMLTHAITRYGIST
                     DDPNKWRYYLDSVEVHLPPFWEQYINDENTVELIHTDSLPLVISLNGHTLQEYMQETR
                     SYALQPVPSTQASIRGEESEQIELLNIRKETHEEYALSRPRGLREALLIVASFLMFFF
                     CLITPDVFVPWLAGGALLLLGAGLWGLFAPPAKSSLREIHCLRGTPRRWGLFGENDQE
                     QINNISLGIIDLVYPAHWQPYIAQDLGQQTDIDIYLDRHVVRQGRYLSLHDEVKNFPL
                     QHWLRSTIIAAGSLLVLFMLLFWIPLDMPLKFTLSWMKGAQTIEATSVKQLADAGVRV
                     GDTLRISGTGMCNIRTSGTWSAKTNSPFLPFDCSQIIWNDARSLPLPESELVNKATAL
                     TEAVNRQLHPKPEDESRVSASLRSAIQKSGMVLLDDFGDIVLKTADLCSAKDDCVRLK
                     NALVNLGNSKDWDALVKRANAGKLDGVNVLLRPVSAESLDNLVATSTAPFITHETARA
                     AQSLNSPAPGGFLIVSDEGSDFVDQPWPSASLYDYPPQEQWNAFQKLAQMLMHTPFNA
                     EGIVTKIFTDANGTQHIGLHPIPDRSGLWRYLSTTLLLLTMLGSAIYNGVQAWRRYQR
                     HRTRMMEIQAYYESCLNPQLITPSESLIE"
     gene            29223..29891
                     /gene="yrfG"
                     /locus_tag="RN951_000554"
     CDS             29223..29891
                     /gene="yrfG"
                     /locus_tag="RN951_000554"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312268.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP/IMP nucleotidase"
                     /protein_id="HDX2525614.1"
                     /translation="MHINIAWQDVDTVLLDMDGTLLDLAFDNYFWQKLVPETWGAKNG
                     VTPQEAMEYMRQQYHDVQHTLNWYCLDYWSEQLGLDICAMTTEMGPRAVLREDTIPFL
                     EALKASGKQRILLTNAHPHNLAVKLEHTGLDAHLDLLLSTHTFGYPKEDQRLWHAVAE
                     ATGLKAERTLFIDDSEAILDAAAQFGIRYCLGVTNPDSGIAEKQYQRHPSLNDYRRLI
                     PSLM"
     gene            29902..30303
                     /gene="hslR"
                     /locus_tag="RN951_000555"
     CDS             29902..30303
                     /gene="hslR"
                     /locus_tag="RN951_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated heat shock protein Hsp15"
                     /protein_id="HDX2525615.1"
                     /translation="MKEKPAVEVRLDKWLWAARFYKTRALAREMIEGGKVHYNGQRSK
                     PSKIVELNATLTLRQGNDERTVIVKAITEQRRPASEAALLYEETAESVEKREKMALAR
                     KLNALTMPHPDRRPDKKERRDLLRFKHGDSE"
     gene            30328..31206
                     /gene="hslO"
                     /locus_tag="RN951_000556"
     CDS             30328..31206
                     /gene="hslO"
                     /locus_tag="RN951_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417860.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HDX2525616.1"
                     /translation="MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNV
                     LAELLVATSLLTATLKFDGDITVQLQGDGPMNLAVINGNNNQQMRGVARVQGEIPENA
                     DLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGD
                     VDGKPAAGGMLLQVMPAQNAQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEV
                     TVYDPQDVEFKCTCSRERCADALKTLPDEEVDSILAEDGEIDMHCDYCGNHYLFNAMD
                     IAEIRNNASPADPQVH"
     gene            complement(31269..32993)
                     /locus_tag="RN951_000557"
     CDS             complement(31269..32993)
                     /locus_tag="RN951_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4153 domain-containing protein"
                     /protein_id="HDX2525617.1"
                     /translation="MDNVELSPATRWGMIATGLLQGLVCYLLIAWLSGKNHSWIVYGV
                     PATVAFSSVLLFSVISFKQKRLWGWLALVFIATLGMSGWLKWQTDGMNPWRAEKALWD
                     FGCYLLLMAMLLLPWIQQSLRIRNDSSRYRYFYQSVWHNVLILLVIFLANGLTWLVLL
                     LWSELFKLVGITFFNTLFFATDWFIYLTLGLVTALAVILARTQSRLIDSIQKLFTLIA
                     TGLLPLVSLLTLMFIITLPFTGLSAISRHISAAGLLLTLAFLQLILMAIVRDPQKASL
                     PWTGPLRCLIKTALLVAPLYVFVAAWALWLRVAQYGWTVDRLQGVLAVLVLLVWSLGY
                     FVSIVWRKGQNPVVLQGKVNLAVSLLVLVILVLLNSPVLDSMRISVNSHMARYQSGKN
                     TSDQVTIYMLEQSGRYGRAALESLKSDAGFMKDPKRARDLLMALDGEQHLQQQVSEKV
                     LADNVLIAPGSVKPDATFWSALIQDRYNVMTCIEKDACVLVEQDLNSDGQAERILFAF
                     NDDRVIVYGFDSDRKEWDALDMSLLPNEITKEKLLTAAKDGKLGTKPKAWRDLVVDGE
                     RLNVNLNE"
     gene            33372..34994
                     /gene="pckA"
                     /locus_tag="RN951_000558"
     CDS             33372..34994
                     /gene="pckA"
                     /locus_tag="RN951_000558"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HDX2525618.1"
                     /translation="MRVNNGLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPSLTGY
                     ERGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTFWWADKGKGKNDNKPLSPETW
                     QHLKGLVTRQLSGKRLFVVDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRPSDEEL
                     AGFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSM
                     MNYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDD
                     GVFNFEGGCYAKTIKLSKEAEPEIYNAIRRDALLENVTVREDGTIDFDDGSKTENTRV
                     SYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKLA
                     GTERGITEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRI
                     SIKDTRAIIDAILNGSLDNAETFTLPMFNLAIPTELPGVDTKILDPRNTYASPEQWQE
                     KAETLAKLFIDNFDKYTDTPAGAALVAAGPKL"
     gene            complement(35070..36422)
                     /gene="envZ"
                     /locus_tag="RN951_000559"
     CDS             complement(35070..36422)
                     /gene="envZ"
                     /locus_tag="RN951_000559"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     EnvZ"
                     /protein_id="HDX2525619.1"
                     /translation="MRRLRFSPRSSFARTLLLIVTLLFASLVTTYLVVLNFAILPSLQ
                     QFNKVLAYEVRMLMTDKLQLEDGTQLVVPPAFRREIYRELGISLYSNEAAEEAGLRWA
                     QHYEFLSHQMAQQLGGPTEVRVEVNKSSPVVWLKTWLSPNIWVRVPLTEIHQGDFSPL
                     FRYTLAIMLLAIGGAWLFIRIQNRPLVDLEHAALQVGKGIIPPPLREYGASEVRSVTR
                     AFNHMAAGVKQLADDRTLLMAGVSHDLRTPLTRIRLATEMMSEQDGYLAESINKDIEE
                     CNAIIEQFIDYLRTGQEMPMEMADLNAVLGEVIAAESGYEREIETALYPGSIEVKMHP
                     LSIKRAVANMVVNAARYGNGWIKVSSGTEPNRAWFQVEDDGPGIAPEQRKHLFQPFVR
                     GDSARTISGTGLGLAIVQRIVDNHNGMLELGTSERGGLSIRAWLPVPVTRAQGTTKEG
                     "
     gene            complement(36419..37138)
                     /gene="ompR"
                     /locus_tag="RN951_000560"
     CDS             complement(36419..37138)
                     /gene="ompR"
                     /locus_tag="RN951_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator OmpR"
                     /protein_id="HDX2525620.1"
                     /translation="MQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLL
                     TRESFHLMVLDLMLPGEDGLSICRRLRSQSNPMPIIMVTAKGEEVDRIVGLEIGADDY
                     IPKPFNPRELLARIRAVLRRQANELPGAPSQEEAVIAFGKFKLNLGTREMFREDEPMP
                     LTSGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAH
                     PRYIQTVWGLGYVFVPDGSKA"
     gene            37366..37842
                     /gene="greB"
                     /locus_tag="RN951_000561"
     CDS             37366..37842
                     /gene="greB"
                     /locus_tag="RN951_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026216.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreB"
                     /protein_id="HDX2525621.1"
                     /translation="MKTPLVTREGYEKLKQELNYLWREERPEVTKKVTWAASLGDRSE
                     NADYQYNKKRLREIDRRVRYLTKCLENLKIVDYSPQQEGKVFFGAWVEIENDDGVTHR
                     FRIVGYDEIFGRKDYISIDSPMARALLKKEVGDLAVVNTPAGEASWYVNAIEYVKP"
     gene            37939..40260
                     /locus_tag="RN951_000562"
     CDS             37939..40260
                     /locus_tag="RN951_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417866.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HDX2525622.1"
                     /translation="MMNDSFCRIIAGEIQARPEQVDAAVRLLDEGNTVPFIARYRKEI
                     TGGLDDTQLRNLETRLSYLRELEERRQAILKSISEQGKLTDDLAKAINATLSKTELED
                     LYLPYKPKRRTRGQIAIEAGLEPLADLLWSDPSHTPEVAAAQYVDADKGVADTKAALD
                     GARYILMERFAEDAALLAKVRDYLWKNAHLVSTVVSGKEEEGAKFRDYFDHHEPLSTV
                     PSHRALAMFRGRNEGVLQLSLNADPQFDEPPKESYCEQIIMDHLGLRLNNAPADSWRK
                     GVVSWTWRIKVLMHLETELMGTVRERAEDEAINVFARNLHDLLMAAPAGLRATMGLDP
                     GLRTGVKVAVVDATGKLVATDTIYPHTGQAAKAAMTVAALCEKHNVELVAIGNGTASR
                     ETERFYLDVQKQFPKVTAQKVIVSEAGASVYSASELAAQEFPDLDVSLRGAVSIARRL
                     QDPLAELVKIDPKSIGVGQYQHDVSQTQLARKLDAVVEDCVNAVGVDLNTASVPLLTR
                     VAGLTRMMAQNIVAWRDENGQFQNRQQLLKVSRLGPKAFEQCAGFLRINHGDNPLDAS
                     TVHPEAYPVVERILAATQQALKDLMGNSSELRNLKASDFTDEKFGVPTVTDIIKELEK
                     PGRDPRPEFKTAQFADGVETMNDLQPGMILEGAVTNVTNFGAFVDIGVHQDGLVHISS
                     LSNKFVEDPHTVVKAGDIVKVKVLEVDLQRKRIALTMRLDEQPGETNARRGGGNERPQ
                     NNRPAAKPRGREAQPAGNSAMMDALAAAMGKKR"
     gene            40717..40944
                     /gene="feoA"
                     /locus_tag="RN951_000563"
     CDS             40717..40944
                     /gene="feoA"
                     /locus_tag="RN951_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transporter A"
                     /protein_id="HDX2525623.1"
                     /translation="MQYTPDTAWKITGFSREISPAYRQKLLSLGMLPGSSFNVVRVAP
                     LGDPIHIETRRVSLVLRKKDLALLEVEAVSC"
     gene            40961..43282
                     /gene="feoB"
                     /locus_tag="RN951_000564"
     CDS             40961..43282
                     /gene="feoB"
                     /locus_tag="RN951_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(2+) transporter permease subunit FeoB"
                     /protein_id="HDX2525624.1"
                     /translation="MKKLTIGLIGNPNSGKTTLFNQLTGSRQRVGNWAGVTVERKEGQ
                     FSTTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNL
                     YLTLQLLELGIPCIVALNMLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALK
                     LAIDRYKANENVELVHYAQPLLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAY
                     AGEASQHLDAALARLRNEMDDPALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDK
                     IVLNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDVGSVALFVHGIQWIGYTLHFPDW
                     LTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGK
                     SFVPLIVGFGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQN
                     GALAVFSLYMLGIVMAVLTGLMLKYTIMRGEATPFVMELPVYHVPHVKSLIIQTWQRL
                     KGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKPIGVHED
                     NWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEEFNPAEFNLGEELFSAIDETWQSL
                     KDTFSLSVLMNPIEASKGDGEMGTGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMG
                     AIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQHPTYSLVCILAVILFNIVVIG
                     LLRRARSRVDIELLATRKSVSSCCAASTTGDCH"
     gene            43282..43518
                     /gene="feoC"
                     /locus_tag="RN951_000565"
     CDS             43282..43518
                     /gene="feoC"
                     /locus_tag="RN951_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[Fe-S]-dependent transcriptional repressor FeoC"
                     /protein_id="HDX2525625.1"
                     /translation="MASLIQVRDLLALRGRMEAAQISQTLNTPQPMINAMLQQLESMG
                     KAVRIQEEPDGCLSGSCKSCPEGKACLREWWALR"
     gene            43721..44599
                     /gene="rpnA"
                     /locus_tag="RN951_000566"
     CDS             43721..44599
                     /gene="rpnA"
                     /locus_tag="RN951_000566"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-promoting nuclease RpnA"
                     /protein_id="HDX2525626.1"
                     /translation="MSKKQSSTPHDALFKLFLRQPDTARDFLAFHLPAPIHALCDMKT
                     LKLESSSFIDDDLRESYSDVLWSVKTEQGPGYIYCLIEHQSTSNKLIAFRMMRYAIAA
                     MQNHLDAGYKTLPMVVPLLFYHGIESPYPYSLCWLDCFADPKLARQLYASAFPLIDVT
                     VMPDDEIMQHRRMALLELIQKHIRQRDLMGLVEQMACLLSSGYANDRQIKGLFNYILQ
                     TGDAVRFNDFIDGVAERSPKHKESLMTIAERLRQEGEQSKALHIAKIMLESGVPLADI
                     MRFTGLSEEELAAASQ"
     gene            complement(44628..45398)
                     /gene="bioH"
                     /locus_tag="RN951_000567"
     CDS             complement(44628..45398)
                     /gene="bioH"
                     /locus_tag="RN951_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pimeloyl-ACP methyl ester esterase BioH"
                     /protein_id="HDX2525627.1"
                     /translation="MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHL
                     VDLPGFGRSRGFGALSLADMAEAVLQQAPDKAIWLGWSLGGLVASQIALTHPERVQAL
                     VTVASSPCFSARDEWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARA
                     LKKTVLALPMPEVDVLNGGLEILKTVDLRQPLQNVSMPFLRLYGYLDGLVPRKVVPML
                     DKLWPHSESYIFAKAAHAPFISHPAEFCHLLVALKQRV"
     gene            45436..46119
                     /gene="gntX"
                     /locus_tag="RN951_000568"
     CDS             45436..46119
                     /gene="gntX"
                     /locus_tag="RN951_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417872.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein GntX"
                     /protein_id="HDX2525628.1"
                     /translation="MLTVPGLCWLCRMPLALGHWGICSVCSRATRTDKTLCPQCGLPA
                     THSHLPCGRCLQKPPPWQRLVTVADYAPPLSPLIHQLKFSRRSEIASALSRLLLLEVL
                     HARRTTGLQLPDRIVSVPLWQRRHWRRGFNQSDLLCQPLSRWLHCQWDSEAVTRTRAT
                     ATQHFLSARLRKRNLKNAFRLELPVQGRHMVIVDDVVTTGSTVAEIAQLLLRNGAAAV
                     QVWCLCRTL"
     gene            46178..46753
                     /gene="nfuA"
                     /locus_tag="RN951_000569"
     CDS             46178..46753
                     /gene="nfuA"
                     /locus_tag="RN951_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016942932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S biogenesis protein NfuA"
                     /protein_id="HDX2525629.1"
                     /translation="MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYC
                     PPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVA
                     DDAPLMERVEYMLQSQINPQLAGHGGRVSLMEITEDGYAILQFGGGCNGCSMVDVTLK
                     EGIEKQLLNEFPELKGVRDLTEHQRGEHSYY"
     gene            47113..48429
                     /gene="gntT"
                     /locus_tag="RN951_000570"
     CDS             47113..48429
                     /gene="gntT"
                     /locus_tag="RN951_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HDX2525630.1"
                     /translation="MPLVIVAIGVILLLLLMIRFKMNGFIALVLVALAVGLMQGMPLD
                     KVIGSIKAGVGGTLGSLALIMGFGAMLGKMLADCGGAQRIATTLIAKFGKKHIQWAVV
                     LTGFTVGFALFYEVGFVLMLPLVFTIAASANIPLLYVGVPMAAALSVTHGFLPPHPGP
                     TAIATIFNADMGKTLLYGTILAIPTVILAGPVYARVLKGIDKPIPEGLYSAKTFSEEE
                     MPSFGVSVWTSLVPVVLMAMRAIAEMILPKGHAFLPVAEFLGDPVMATLIAVLIAMFT
                     FGLNRGRSMDQINDTLVSSIKIIAMMLLIIGGGGAFKQVLVDSGVDKYIASMMHETNI
                     SPLLMAWSIAAVLRIALGSATVAAITAGGIAAPLIATTGVSPELMVIAVGSGSVIFSH
                     VNDPGFWLFKEYFNLTIGETIKSWSMLETIISVCGLVGCLLLNMVI"
     gene            complement(48540..50624)
                     /gene="malQ"
                     /locus_tag="RN951_000571"
     CDS             complement(48540..50624)
                     /gene="malQ"
                     /locus_tag="RN951_000571"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HDX2525631.1"
                     /translation="MESKRLDNAALAAGISPNYINAHGKPQSISAETKRRLLDAMHQR
                     TATKVAVTPVPNVMVYTSGKKMPMVVEGSGEYSWLLTTEEGTQYKGHVTGGKAFNLPT
                     KLPEGYHTLTLTQDDQRAHCRVIVAPKRCYEPQALLNKQKLWGACVQLYTLRSEKNWG
                     IGDFGDLKAMLVDVAKRGGSFIGLNPIHALYPANPESASPYSPSSRRWLNVIYIDVNA
                     VEDFHLSEEAQAWWQLPTTQQTLQQARDADWVDYSTVTALKMTALRMAWKGFAQRDDE
                     QMAAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAWPEMYQNVDSPEVRQFC
                     EEHRDDVDFYLWLQWLAYSQFAACWEISQGYEMPIGLYRDLAVGVAEGGAETWCDREL
                     YCLKASVGAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLRANMQNCGALRIDHV
                     MSMLRLWWIPYGETADQGAYVHYPVDDLLSILALESKRHRCMVIGEDLGTVPVEIVGK
                     LRSSGVYSYKVLYFENDHEKTFRAPKAYPEQSMAVAATHDLPTLRGYWESGDLTLGKT
                     LGLYPDEVVLRGLYQDRELAKQGLLDALHKYGCLPKRAGHKASLMSMTPTLNRGLQRY
                     IADSNSALLGLQPEDWLDMAEPVNIPGTSYQYKNWRRKLSATLESMFADDGVNKLLKD
                     LDRRRRAAAKKK"
     gene            complement(50634..53027)
                     /gene="malP"
                     /locus_tag="RN951_000572"
     CDS             complement(50634..53027)
                     /gene="malP"
                     /locus_tag="RN951_000572"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin phosphorylase"
                     /protein_id="HDX2525632.1"
                     /translation="MSQPIFNDKQFQEALSRQWQRYGLNSAAEMTPRQWWLAVSEALA
                     EMLRAQPFAKPVANQRHVNYISMEFLIGRLTGNNLLNLGWYQDVQDSLKAYDINLTDL
                     LEEEIDPALGNGGLGRLAACFLDSMATVGQSATGYGLNYQYGLFRQSFVDGKQVEAPD
                     DWHRSNYPWFRHNEALDVQVGIGGKVTKDGRWEPEFTITGQAWDLPVVGYRNGVAQPL
                     RLWQATHAHPFDLTKFNDGDFLRAEQQGINAEKLTKVLYPNDNHTAGKKLRLMQQYFQ
                     CACSVADILRRHHLAGRKLHELADYEVIQLNDTHPTIAIPELLRVLIDEHQMSWDDAW
                     AITSKTFAYTNHTLMPEALERWDVKLVKGLLPRHMQIINEINTRFKTLVEKTWPGDEK
                     VWAKLAVVHDKQVHMANLCVVGGFAVNGVAALHSDLVVKDLFPEYHQLWPNKFHNVTN
                     GITPRRWIKQCNPALAALLDKSLQKEWANDLDQLINLEKFADDAKFRQQYREIKQANK
                     VRLAEFVKVRTGIEINPQAIFDIQIKRLHEYKRQHLNLLHILALYKEIRENPQADRVP
                     RVFLFGAKAAPGYYLAKNIIFAINKVADVINNDPLVGDKLKVVFLPDYCVSAAEKLIP
                     AADISEQISTAGKEASGTGNMKLALNGALTVGTLDGANVEIAEKVGEENIFIFGHTVE
                     QVKAILAKGYDPVKWRKKDKVLDAVLKELESGKYSDGDKHAFDQMLHSIGKQGGDPYL
                     VMADFAAYVEAQKQVDVLYRDQEAWTRAAILNTARCGMFSSDRSIRDYQARIWQAKR"
     gene            53639..56344
                     /gene="malT"
                     /locus_tag="RN951_000573"
     CDS             53639..56344
                     /gene="malT"
                     /locus_tag="RN951_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MalT"
                     /protein_id="HDX2525633.1"
                     /translation="MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYG
                     KTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAVQQATNGHCAICETMAQKRQY
                     ASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSR
                     NLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGW
                     ATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAI
                     LRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQW
                     ELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSL
                     LEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREDTMHAE
                     FNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSL
                     ALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQL
                     PMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGD
                     LDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFA
                     NNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQ
                     AGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRI
                     LREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQI
                     AGELEVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV"
     gene            complement(56387..57403)
                     /gene="rtcA"
                     /locus_tag="RN951_000574"
     CDS             complement(56387..57403)
                     /gene="rtcA"
                     /locus_tag="RN951_000574"
                     /EC_number="6.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 3'-terminal phosphate cyclase"
                     /protein_id="HDX2525634.1"
                     /translation="MKRMIALDGAQGEGGGQILRSALSLSMITGQPFTITSIRAGRAK
                     PGLLRQHLTAVKAATEICGATVEGAELGSQRLLFRPGTVRGGDYRFAIGSAGSCTLVL
                     QTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFY
                     PAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLAGSFSL
                     HEQNIHNLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLAS
                     TAAVGEYLADQLVLPMALAGAGEFTVAHPSCHLLTNIAVVERFLPVRFSLIETDGVTR
                     VSIE"
     gene            complement(57407..58633)
                     /gene="rtcB"
                     /locus_tag="RN951_000575"
     CDS             complement(57407..58633)
                     /gene="rtcB"
                     /locus_tag="RN951_000575"
                     /EC_number="6.5.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-splicing ligase RtcB"
                     /protein_id="HDX2525635.1"
                     /translation="MNYELLTTENAPVKMWTKGVPVEADARQQLINTAKMPFIFKHIA
                     VMPDVHLGKGSTIGSVIPTKGAIIPAAVGVDIGCGMNALRTALTAEDLPENLAELRQA
                     IETAVPHGRTTGRCKRDKGAWENPPVNVDAKWAELEAGYQWLTQKYPRFLNTNNYKHL
                     GTLGTGNHFIEICLDESDQVWIMLHSGSRGIGNAIGTYFIDLAQKEMQETLETLPSRD
                     LAYFMEGTEYFDDYLKAVAWAQLFASLNRDAMMENVVTALQSITQKTVRQPQTLAMEE
                     INCHHNYVQKEQHFGEEIYVTRKGAVSARAGQYGIIPGSMGAKSFIVRGLGNEESFCS
                     CSHGAGRVMSRTKAKKLFSVEDQIRATAHVECRKDAEVIDEIPMAYKDIDAVMAAQSD
                     LVEVIYTLRQVVCVKG"
     gene            58822..60420
                     /gene="rtcR"
                     /locus_tag="RN951_000576"
     CDS             58822..60420
                     /gene="rtcR"
                     /locus_tag="RN951_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator RtcR"
                     /protein_id="HDX2525636.1"
                     /translation="MRKTVAFGFVGTVLDYAGRGSQRWSKWRPTLCLCQQESLVIDRL
                     ELLHDARSRSLFETLKRDIASVSPETEVVSVEIELHNPWDFEEVYACLHDFARGYEFQ
                     PEKEDYLIHITTGTHVAQICWFLLAEARYLPARLIQSSPPRKKEQPRGPGEVTIIDLD
                     LSRYNAIASRFAEERQQTLDFLKSGIATRNPHFNRMIEQIEKVAIKSRAPILLNGPTG
                     AGKSFLARRIFELKQARHQFSGAFVEVNCATLRGDTAMSTLFGHVKGAFTGARESREG
                     LLRSANGGMLFLDEIGELGADEQAMLLKAIEEKTFYPFGSDRQVSSDFQLIAGTVRDL
                     RQLVAEGKFREDLYARINLWTFTLPGLRQRQEDIEPNLDYEVERHASLTGDSVRFNTE
                     ARRAWLAFATSPQATWRGNFRELSASVTRMATFATSGRITLDVVEDEINRLRYNWQES
                     RPSALTALLGAEAENIDLFDRMQLEHVIAICRQAKSLSAAGRQLFDVSRQGKASVNDA
                     DRLRKYLARFGLTWEAVQDQHSSS"
     gene            complement(60402..61160)
                     /locus_tag="RN951_000577"
     CDS             complement(60402..61160)
                     /locus_tag="RN951_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family transcriptional regulator"
                     /protein_id="HDX2525637.1"
                     /translation="MKQTQRHNGIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNELA
                     EQNLILRHHGGAALPSSSVNTPWHDRKATQTEEKERIARKVAEQISNGSTLFIDIGTT
                     PEAVAHALLNHSNLRIVTNNLNVANTLMVKEDFRIILAGGELRSRDGGIIGEATLDFI
                     SQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVN
                     MGSISMVDAVYTDAPPPVSVMQVLTDHHIQLELC"
     gene            complement(61177..62007)
                     /gene="glpG"
                     /locus_tag="RN951_000578"
     CDS             complement(61177..62007)
                     /gene="glpG"
                     /locus_tag="RN951_000578"
                     /EC_number="3.4.21.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease
                     GlpG"
                     /protein_id="HDX2525638.1"
                     /translation="MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQ
                     AERVRAELARFLENPADPRYLAASWQAGHTGSGLHYRRYPFFAALRERAGPVTWVMMI
                     VCVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWY
                     LGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERD
                     PQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
                     "
     gene            complement(62052..62378)
                     /gene="glpE"
                     /locus_tag="RN951_000579"
     CDS             complement(62052..62378)
                     /gene="glpE"
                     /locus_tag="RN951_000579"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase GlpE"
                     /protein_id="HDX2525639.1"
                     /translation="MDQFECINVADAHQKLQEKEAVLVDIRDPQSFAMGHAVQAFHLT
                     NDTLGAFMRDNDFDTPVMVMCYHGNSSKGAAQYLLQQGYDVVYSIDGGFEAWQRQFPA
                     EVAYGA"
     gene            62568..64073
                     /gene="glpD"
                     /locus_tag="RN951_000580"
     CDS             62568..64073
                     /gene="glpD"
                     /locus_tag="RN951_000580"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase"
                     /protein_id="HDX2525640.1"
                     /translation="METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSA
                     SSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIR
                     IGLFMYDHLGKRTSLPGSTGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVV
                     RKGGEVLTRTRATSARRENGLWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGM
                     HLPSPYGIRLIKGSHIVVPRVHTQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYK
                     GDPKAVKIEESEINYLLNVYNTHFKKQLSRDDIVWTYSGVRPLCDDESDSPQAITRDY
                     TLDIHDENGKAPLLSVFGGKLTTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIE
                     GDRDDYAARLRRRYPFLTESLARHYARTYGSNSELLLGNAGTVSDLGEDFGHEFYEAE
                     LKYLVDHEWVRRADDALWRRTKQGMWLNADQQSRVSQWLVEYTQQRLSLAS"
     gene            complement(64342..64563)
                     /locus_tag="RN951_000581"
                     /pseudo
     CDS             complement(64342..64563)
                     /locus_tag="RN951_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312299.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
     gene            complement(64689..67136)
                     /gene="glgP"
                     /locus_tag="RN951_000582"
     CDS             complement(64689..67136)
                     /gene="glgP"
                     /locus_tag="RN951_000582"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen phosphorylase"
                     /protein_id="HDX2525641.1"
                     /translation="MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNA
                     TLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFLIGRTLSNAMLSLGIYEDVQGAL
                     EAMGLNLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNI
                     VNGSQKESPDYWLEYGNPWEFKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQ
                     IIPGYDTDATNTLRLWSAQASSEINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTY
                     SGRELRLRQEYFLVSSTIQDILSRHYQLHKTYDNLADKIAIHLNDTHPVLSIPEMMRL
                     LIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYF
                     LKTLQEQYPNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLF
                     ADFAKIFPGRFTNVTNGVTPRRWLAVANPSLSAVLDEHLGRNWRTDLSLLNELQQHCD
                     FPMVNHAVHQAKLENKKRLAEYIAQQLNVVVNPKALFDVQIKRIHEYKRQLMNVLHVI
                     TRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKV
                     VFIPNYSVSLAQLIIPAADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEML
                     DHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEELHQVLTQIGSGVFSPEDPGRY
                     RDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYELQEEWTAKAMLNIANMGYFSSDR
                     TIKEYADHIWHIDPVRL"
     gene            complement(67155..68588)
                     /gene="glgA"
                     /locus_tag="RN951_000583"
     CDS             complement(67155..68588)
                     /gene="glgA"
                     /locus_tag="RN951_000583"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HDX2525642.1"
                     /translation="MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDARVLLPAF
                     PDIRRGVTDAQVVSRRDTFAGHITLLFGHYNGVGIYLIDAPHLYDRPGSPYHDTNLFA
                     YTDNVLRFALLGWVGAEMASGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTV
                     HNLAYQGMFYAHHMNDIQLPWSFFNIHGLEFNGQISFLKAGLYYADHITAVSPTYARE
                     ITEPQFAYGMEGLLQQRHREGRLSGVLNGVDEKIWSPETDLLLASRYTRDTLEDKAEN
                     KRQLQIAMGLKVDDKVPLFAVVSRLTSQKGLDLVLEALPGLLEQGGQLALLGAGDPVL
                     QEGFLAAAAEYPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTL
                     PLVRRTGGLADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRF
                     VQRQAMAMDFSWQVAAKSYRELYYRLK"
     gene            complement(68588..69883)
                     /gene="glgC"
                     /locus_tag="RN951_000584"
     CDS             complement(68588..69883)
                     /gene="glgC"
                     /locus_tag="RN951_000584"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HDX2525643.1"
                     /translation="MVSLEKNDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPA
                     VHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLL
                     PAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKG
                     ARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVF
                     DADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRD
                     VGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLV
                     SGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPE
                     GMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER"
     gene            complement(69901..71874)
                     /gene="glgX"
                     /locus_tag="RN951_000585"
     CDS             complement(69901..71874)
                     /gene="glgX"
                     /locus_tag="RN951_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen debranching protein GlgX"
                     /protein_id="HDX2525644.1"
                     /translation="MTQLAIGKPAPLGAHYDGQGVNFTLFSAHAERVELCVFDANGQE
                     HRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIDG
                     EFKDNPLLHAGHNEPDYRDNAAIAPKCVVVVDHYDWEDDAPPRTPWGSTIIYEAHVKG
                     LTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNY
                     WGYNPVAMFALHPAYACSPETALDEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPL
                     FSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYASACLRYWVETCHVDGFR
                     FDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEW
                     NDHFRDAARRFWLHYDLPLGAFAGRFAASSDVFKRNGRLPSAAINLVTAHDGFTLRDC
                     VCFNHKHNEANGEENRDGTNNNYSNNHGKEGLGGSLDLVERRRDSIHALLTTLLLSQG
                     TPMLLAGDEHGHSQHGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALVE
                     NRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPA
                     GEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR"
     gene            complement(71871..74057)
                     /gene="glgB"
                     /locus_tag="RN951_000586"
     CDS             complement(71871..74057)
                     /gene="glgB"
                     /locus_tag="RN951_000586"
                     /EC_number="2.4.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching enzyme"
                     /protein_id="HDX2525645.1"
                     /translation="MSDRIDRDVINALIAGHFADPFSVLGMHKTTAGLEVRALLPDAT
                     DVWVIEPKTGRKLAKLECLDSRGFFSGVIPRRKNFFRYQLAVVWHGQQNLIDDPYRFG
                     PLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWD
                     GRRHPMRLRKESGIWELFIPGAHNGQLYKYEMIDANGNLRLKSDPYAFEAQMRPETAS
                     LICGLPEKVVQTEERKKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYA
                     KWMGFTHLELLPINEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFIDAAHAAGLNVIL
                     DWVPGHFPTDDFALAEFDGTNLYEHSDPREGYHQDWNTLIYNYGRREVSNFLVGNALY
                     WIERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRILGEQV
                     SGAVTMAEESTDFPGVSRPQDMGGLGFWYKWNLGWMHDTLDYMKLDPVYRQYHHDKLT
                     FGILYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLL
                     FMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNLTYRHHKAMHELDFDPY
                     GFEWLVVDDKERSVLIFVRRDKEGNEIIVASNFTPVPRHDYRFGINQPGKWREILNTD
                     SMHYHGSNAGNGGTVHSDEIASHGRQHSLSLTLPPLATIWLVREAE"
     gene            complement(74330..75433)
                     /gene="asd"
                     /locus_tag="RN951_000587"
     CDS             complement(74330..75433)
                     /gene="asd"
                     /locus_tag="RN951_000587"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDX2525646.1"
                     /translation="MKNVGFIGWRGMVGSVLMQRMVEERDFDAIRPVFFSTSQLGQAA
                     PSFGGTTGTLQDAFDLEALKALDIIVTCQGGDYTNEIYPKLRESGWQGYWIDAASSLR
                     MKDDAIIILDPVNQDVITDGLNNGIRTFVGGNCTVSLMLMSLGGLFANDLVDWVSVAT
                     YQAASGGGARHMRELLTQMGHLYGHVADELATPSSAILDIERKVTTLTRSGELPVDNF
                     GVPLAGSLIPWIDKQLDNGQSREEWKGQAETNKILNTSSVIPVDGLCVRVGALRCHSQ
                     AFTIKLKKDVSIPTVEELLAAHNPWAKVVPNDREITMRELTPAAVTGTLTTPVGRLRK
                     LNMGPEFLSAFTVGDQLLWGAAEPLRRMLRQLA"
     gene            75626..76219
                     /gene="yhgN"
                     /locus_tag="RN951_000588"
     CDS             75626..76219
                     /gene="yhgN"
                     /locus_tag="RN951_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter YhgN"
                     /protein_id="HDX2525647.1"
                     /translation="MNEIISAAVLLILIMDPLGNLPIFMSVLKHTEPKRRRAIMVREL
                     LIALLVMLVFLFAGEKILAFLSLRAETVSISGGIILFLIAIKMIFPSASGNSSGLPAG
                     EEPFIVPLAIPLVAGPTILATLMLLSHQYPNQMGHLVIALLLAWGGTFVILLQSSLFL
                     RLLGEKGVNALERLMGLILVMMATQMFLDGIRMWMKG"
     gene            complement(76276..77616)
                     /gene="gntU"
                     /locus_tag="RN951_000589"
     CDS             complement(76276..77616)
                     /gene="gntU"
                     /locus_tag="RN951_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HDX2525648.1"
                     /translation="MTTLTLVLTAVGSVLLLLFLVMKARMHAFLALMVVSMGAGLFSG
                     MPLDKIAATMEKGMGGTLGFLAVVVALGAMFGKILHETGAVDQIAVKMLKSFGHSRAH
                     YAIGLAGLVCALPLFFEVAIVLLISVAFSMARHTGTNLVKLVIPLFAGVAAAAAFLVP
                     GPAPMLLASQMNADFGWMILIGLCAAIPGMIIAGPLWGNFISRYVELHIPDDISEPHL
                     GEGKMPSFGFSLSLILLPLVLVGLKTIAARFVPEGSTAYEWFEFIGHPFTAILVACLV
                     AIYGLAMRQGMPKDKVMEICGHALQPAGIILLVIGAGGVFKQVLVDSGVGPALGEALT
                     GMGLPIAITCFVLAAAVRIIQGSATVACLTAVGLVMPVIEQLNYSGAQMAALSICIAG
                     GSIVVSHVNDAGFWLFGKFTGATEAETLKTWTMMETILGTVGAIVGMIAFQLLS"
     gene            complement(77620..78147)
                     /gene="gntK"
                     /locus_tag="RN951_000590"
     CDS             complement(77620..78147)
                     /gene="gntK"
                     /locus_tag="RN951_000590"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HDX2525649.1"
                     /translation="MSTTNHDHHIYVLMGVSGSGKSAVASEVAHQLHAAFLDGDFLHP
                     RRNIEKMASGEPLNDDDRKPWLQALNDAAFAMQRTNKVSLIVCSALKKHYRDLLREGN
                     PNLSFIYLKGDFDVIESRLKARKGHFFKTQMLVTQFETLQEPGADETDVLVVDIDQPL
                     EGVVASTIEVIKKGK"
     gene            complement(78286..79281)
                     /gene="gntR"
                     /locus_tag="RN951_000591"
     CDS             complement(78286..79281)
                     /gene="gntR"
                     /locus_tag="RN951_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001693277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate operon transcriptional repressor GntR"
                     /protein_id="HDX2525650.1"
                     /translation="MKKKRPVLQDVADRVGVTKMTVSRFLRNPEQVSVALRGKIAAAL
                     DELGYIPNRAPDILSNATSRAIGVLLPSLTNQVFAEVLRGIESVTDAHGYQTMLAHYG
                     YKPEMEQERLESMLSWNIDGLILTERTHTPRTLKMIEVAGIPVVELMDSKSPCLDIAV
                     GFDNFEAARQMTTAIIARGHRHIAYLGARLDERTIIKQKGYEQAMLDAGLVPYSVMVE
                     QSSSYSSGIELIRQARREYPQLDGVFCTNDDLAVGAAFECQRLGLKVPDDMAIAGFHG
                     HDIGQVMEPRLASVLTPRERMGSIGAERLLARIRGESVTPKMLDLGFTLSPGGSI"
     gene            complement(79505..80200)
                     /gene="yhhW"
                     /locus_tag="RN951_000592"
     CDS             complement(79505..80200)
                     /gene="yhhW"
                     /locus_tag="RN951_000592"
                     /EC_number="1.13.11.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004213399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quercetin 2,3-dioxygenase"
                     /protein_id="HDX2525651.1"
                     /translation="MIYLRKANERGHANHGWLDSWHTFSFANYYDPNFMGFSALRVIN
                     DDVIEAGQGFGTHPHKDMEILTYVLEGTVEHQDSMGNKEQVPAGEFQIMSAGTGIRHS
                     EYNPSSTERLHLYQIWIMPEENGITPRYEQRRFDAVQGKQLVLSPDARDGSLKVHQDM
                     ELYRWALLKDEQSVHQIAAERRVWIQVVKGNVTINGVKASTSDGLAIWDEQAISIHAD
                     SDSEVLLFDLPPV"
     gene            complement(80323..81360)
                     /locus_tag="RN951_000593"
     CDS             complement(80323..81360)
                     /locus_tag="RN951_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDX2525652.1"
                     /translation="MVINCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQ
                     APIYSHIHFTSDLDEVLNDPDVKLVVVCTHADSHFEYAKRALEAGKNVLVEKPFTPTL
                     AQAKELFALAKSKGLTVTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVA
                     ETKPGLPQDGAFYGLGVHTMDQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGD
                     LKAIVKTSHLVKIDYPKFIVHGKKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGV
                     LEYVNDEGVTVREEMKPEMGDYGRVYDALYQTITHGAPNYVKESEVLTNLEILERGFE
                     QASPSTVTLAK"
     gene            81693..82181
                     /gene="yhhY"
                     /locus_tag="RN951_000594"
     CDS             81693..82181
                     /gene="yhhY"
                     /locus_tag="RN951_000594"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDX2525653.1"
                     /translation="MSEIVIRHAETRDYEAIRQIHAQPEVYCNTLQVPHPSDHMWQER
                     LADRPGIKQLVACIDGDVVGHLTIDVQQRPRRSHVADFGICVDSRWKNRGVASALMRE
                     MIEMCDNWLRVDRIELTVFVDNAPAIKVYKKYGFEIEGTGKKYALRNGEYVDAYYMAR
                     VK"
     gene            82418..>82632
                     /gene="hcp"
                     /locus_tag="RN951_000595"
     CDS             82418..>82632
                     /gene="hcp"
                     /locus_tag="RN951_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tube protein Hcp"
                     /protein_id="HDX2525654.1"
                     /translation="MSNIVYLTVTGEQQGSISAGCGTSESTGNRWQSGHEDEIFTFSL
                     LNNINNTGLGSQFHGITFCKLIDKSTP"
BASE COUNT        19786 a        22609 c        20886 g        19351 t
ORIGIN      
        1 aatgaacaaa tttattaaag ttgcactggt aggtgcagta ctggctacgt taactgcatg
       61 tactggtcat attgaaaacc gtgataagaa ctgctcttac gactacctgc tgcacccggc
      121 aatttctatt tctaaaatca ttggcggttg cggtcctact gcacagtaag tctctgacag
      181 aaatcggcta acaccggttt aattgcccga cgccctctgg attttccgag ggcgtatttg
      241 tttctatgtc cttcttgccc ccgcccgtaa aaatattttc actttaaatt caatttgata
      301 actacatcca ttagccacag cgcgatcctg tgcgaaattt tgtgatcttc ctccacatta
      361 cataacatca tatgttgtta tattcatcat gcattgtcat gttacctttt aaatgactgc
      421 aaactctccc ctacaacgta ttggacaaga aaaaggtatc gctatgggaa gccaggaact
      481 ccaacgcaag ctcggatttt gggccgttct tgcaatcgcc gtcgggacaa ccgtcggctc
      541 cggtattttt gtatctgtgg gtgaagtggc aaaagcagcg ggcacgccgt ggcttacggt
      601 gctcgcgttt gtcattggcg ggttaattgt gatcccgcaa atgtgcgtct atgcggaact
      661 atccaccgct tatccggaaa atggcgcaga ttatgtttat ctgaaaaatg ccggaagccg
      721 accgctggct ttcctctccg gctgggccag cttctgggac aacgatgcgc cgtcattgtc
      781 gattatggcg ctggcgattg tcagcaatct tggcttttta acgcctatcg atccgttgct
      841 cggtaaattt atcgccgccg gattaattat cgcctttatg ttgctacacc tgcgctccgt
      901 tgaaggcggc gcagcgtttc agacgctaat taccatcgcc aaaattatcc cgttcactat
      961 cgtcattggc cttgggatct tctggtttaa agcggagaat tttgccgccc ctaccaccac
     1021 tgcgattggc gcaacgggca gctttatggc gctgctggcg gggatctctg ccaccagttg
     1081 gtcgtatacc ggcatggcct ctatctgtta tatgaccggc gaaattaaaa accccggaaa
     1141 aaccatgcca cgagcgctga ttggttcctg tctgctggtt ctggtgctct acaccctgct
     1201 ggcgctggtg atttccggcc tgatgccctt cgacaaactc gccaattctg aaacgccgat
     1261 ttccgacgcc ctgacctgga tccccgcact cggcagcacc gctgggatct ttgttgccat
     1321 cacggcgatg atcgtcattc ttggttcgct ttccagctgc gtgatgtacc agccgcggct
     1381 ggaatacgcg atggcgaaag acaacctgtt ctttaaatgc ttcggccatg tgcatccgaa
     1441 atacaacacg ccggatgtct ccatcatcct gcaaggggcg ctggggatct tcttcatctt
     1501 cgtttccgat ctcaccagcc tgctgggtta tttcaccctg gtgatgtgtt tcaaaaatac
     1561 cctcaccttc ggctccatca tctggtgtcg taaacgcgac gattacaaac cgctgtggcg
     1621 tactccggct ttcgggctga tgaccaccct cgccattgcg tcaagcctca ttctggtcgc
     1681 ctcaaccttt gtctgggcac cgattcccgg ccttatctgc gccgtcatcg ttattgctac
     1741 tggtctgcct gcttacgcct tctgggcgaa gcgtagccgc cagctcaacg ctttgtcgta
     1801 atgttatctg gagaaaataa aatgttggat attgataaaa gcaccgtgga ctttctggtc
     1861 accgaaaata tggttcagga agtggaaaaa gttctcagcc atgacgttcc gctggtgcac
     1921 gccatcgtgg aagagatggt gaagcgcgac attgatcgta tttatttcgt tgcctgcgga
     1981 tcgccactca acgcggcgca aacggcgaaa catctggcgg atcgcttttc cgatcttcag
     2041 gtctacgcca tttccggctg ggagttctgc gataacaccc cgtatcgcct cgacgatcgt
     2101 tgcgcagtaa ttggcgtttc tgactacggt aaaaccgaag aggtaatcaa agcgctggag
     2161 ctgggccggg cctgcggcgc actcactgcg gcgttcacca aacgcgcgga tagcccgatt
     2221 acctcggcgg cggaatttag cattgattat caggccgact gtatctggga aattcacctg
     2281 ctgctctgct acagcgtggt gctggagatg atcacccgcc tcgcgccgaa cgcggaaatc
     2341 ggcaagatca aaaacgatct caagcagttg ccgaatgcgc tcggtcatct ggtacgcacc
     2401 tgggaagaaa aaggccgcca gcttggtgaa ctggccagcc agtggccgat gatttatacc
     2461 gttgctgcgg gtccgctgcg tccgctgggt tacaaagaag gcattgtaac gctgatggaa
     2521 tttacctgga cgcacggctg cgtgattgag agcggagagt tccgccatgg cccgctggag
     2581 attgtcgaac cgggcgttcc gttcctgttc ctgctcggca atgatgaaag tcgccacacc
     2641 accgaacgcg ccattaactt tgttaaacag cgtactgaca acgtgatcgt catcgattac
     2701 gccgaaattt cgcaagggct gcacccgtgg ctggcaccgt tcctgatgtt cgtgccaatg
     2761 gagtggctct gctactacct gtctatttac aaagatcaca acccggatga acgccgctat
     2821 tacggtggtc tggtggaata ttaatccctc tcccggcccg gcaacggggc ggatttacgc
     2881 aaggagttac ccgatgaaaa caggtatgtt tacctgcggc caccagcggc tgcctattga
     2941 acacgcattt cgtgatgcaa gcgagctggg ttacgacggc atcgaaattt ggggcggtcg
     3001 cccgcacgcg ttcgcgccgg acttaaaagc gggcggcatc aaacaaatca aggcgctggc
     3061 gcagacgtat cagatgccga ttatcggcta tacgccagaa accaacggct atccgtataa
     3121 catgatgctg ggcgatgaac atatgcgtcg cgaaagcctc gacatgatca agctggcgat
     3181 ggatatggca aaagagatga acgcgggtta tacgctgatt tccgcggccc acgcgggcta
     3241 tctcacgcca cctaatgtta tctggggacg gctggcagag aacctaagcg aactgtgtga
     3301 gtacgcggaa aacatcggca tggatctaat cctcgaaccg ttaacgccgt atgaatcgaa
     3361 cgtcgtgtgt aatgctaatg atgtgcttca tgcgctggcg ctggtgcctt cgccgcgcct
     3421 gttcagcatg gtcgacattt gcgcgccgta tgtccaggcg gaaccggtga tgagttattt
     3481 cgacaaactg ggcgataaat tacgtcatct gcatattgtc gacagcgacg gggccagcga
     3541 cacgcattac attcctggag aaggcaaaat gccgctgcgg gaactgatgc gcgatattat
     3601 tgagcggggc tatgagggtt actgtacggt ggagctggtg acgatgtata tgaacgagcc
     3661 cagactctat gcccgccagg cgctggaacg ctttcgcgcg ctgctgccgg aggatgagag
     3721 atgaaaaccc tggcgacaat cggcgataac tgcgtcgata tctacccgca actgaataaa
     3781 gcgttttctg gcggtaatgc ggtcaatgtg gcggtgtact gcactcgcta cggcatacag
     3841 ccgggatgca ttacctgggt gggtgacgat gactacggca caaagctgaa gcaggatctc
     3901 gcccgcatgg gcgtcgatat cagccatgtc catacgaaac acggcgttac cgcacaaact
     3961 caggtggaac tgcacgacaa tgatcgcgtt tttggcgact acaccgaagg cgtgatggcc
     4021 gactttgccc tgagtgaaga ggattacgcc tggctggcgc agtatgacat tgtgcacgcg
     4081 gcaatctggg gacatgcgga agacgcattc ccacagctgc acgctgcggg caaacttacc
     4141 gctttcgact tctccgacaa gtgggacagc ccgctctggc agacactggt gccgcatctc
     4201 gattttgcct ttgcctccgc accgcaagaa gacgaaacgc tgcgtctgaa gatgaaagcg
     4261 attgttgccc gtggcgcagg aacagtgatt gtcacgctgg gtgaaaacgg cagcattgcc
     4321 tgggatggcg cgcagttctg gcgtcaggct cctgaaccgg tgacggttat cgacaccatg
     4381 ggtgccggag attcgttcat tgccggattc ctttgcggct ggtctgcggg gatgacatta
     4441 ccgcaggcga tagcgcaggg aacggcgtgc gcggcgaaaa ccattcagta ccacggtgcc
     4501 tggtaggtat aacgttggcg tgagcatctt cacgccaacg tgctgttact tgccggaaaa
     4561 cgaccctata atccgagtaa ttcattcttt atttcagggt cgattatgtc agctacggac
     4621 cgctactctc atcaactcct ctacgctacc gtccgccagc gactgctgga tgatatcgcg
     4681 cagggggttt accaggccgg gcaacagatc cctaccgaaa acgagctttg tacacaatat
     4741 aacgtcagcc gcattaccat tcgcaaagcc atcagcgact tagtggcaga cggcgtactg
     4801 atccgctggc agggaaaagg cacctttgta caaagccaga aagttgaaaa cgccctgctt
     4861 actgtcagtg gttttaccga ttttggcgtc tcacaaggca aggcgacgaa agagaaagtg
     4921 atcgaacagg aacgggtcag cgccgcgccg ttttgcgaaa agctgaacat ccccggaaac
     4981 agcgaagtgt tccatctctg ccgggtgatg tatctcgata aagagccgct gtttattgat
     5041 agttcatgga tcccgctgtc gcgttatcct gactttgatg agatttacgt cgaaggaagc
     5101 tccacctatc agttatttca ggagcgtttt gacacgcgag tggtcagcga caaaaagacc
     5161 atcgatatct ttgccgccac ccgcccgcag gcaaaatggc tgaaatgcga actgggcgaa
     5221 ccgttgtttc gcatcagcaa aatcgccttt gatcagaatg acaaaccggt gcacgtctcc
     5281 gaactcttct gccgcgccaa tcgcatcacc ttaactattg ataataaaag acattaaccg
     5341 taggccggat aagatgcgcc agcatcgcat ccggcgatgc tggcgcgttg aattttacat
     5401 cccgtacgtt cccctcaccc taaccctctc cccaaagggg cgaggggacc gttcagtacg
     5461 gaatttagct tgacggtgct atccagcatt aaatactggc aatactctca cgcaaaatcc
     5521 gcagcaccgt ctcttcaccg ctgcgattcg ggttaatgcg aatcgcacaa tgttctgatt
     5581 gtggattcgc ctggcgaaac gttccggaaa ggcgataaaa gagcggcggg atttcatatt
     5641 tcgactctgc acccaccggg taaggcaagg caccgcgctt ttgcgcctct tccagcactc
     5701 tggcggcaat cggctgatga aactcgacaa tcaacacctt cgactgcgca ttagcaatca
     5761 ccgcgctttt cacttccggc accgcaccac cgttaagcaa agccagcaac cgttcagata
     5821 cccctgcctg caccgcgtgc atcactggcg caaacaccag accacgcaat acttccagcg
     5881 cctgtgcgcc ctggatctgg ctaccgccgg agtaaagcgt ggcgcgaata cggttgataa
     5941 catcagcatc gccgaccact gcaccaacac cctctggccc aaatagcttg aagcaggaaa
     6001 atgtcgagac attcgcgccg cattcacagc cgattcgagc caccttcatc accgcatagt
     6061 tgtcatcggt taacgctgga acacctgccg cgcgcaacgt tgccagcaca tctgccagca
     6121 cgtagctgtc ctgcggctgc tggcgcgtat gctgcaccag cgccgcatcc ggttgttgct
     6181 cgtcgacgac ctgcttcagt gccgacaggt cattgaaatc aacagtaata agcgtcagcc
     6241 ccatctgctc aataataacc cgtgtcgtcg ggtaaacagg cgcgtcatgc accagaagac
     6301 gctgccccgg tttgagcaaa gccgccagcc cggcgcgaat cgcgccagtc cccgcgccct
     6361 gcaccagcgc cgcagcctgt gcgtgaaatg catcagccag cacctgttcc acacgctggg
     6421 taacgcgcgg ttgattcagt cctggcgtta agcctaaatc accgccagta agaaactcgc
     6481 tgccggggaa atggcgacaa atgctatcca ccagcgcaaa ctgcttttgc tgcgcctcaa
     6541 taatcgtcag gctttgcaga ggaaacgtct tcataggtgc cttccttaag ccggaacgaa
     6601 caggccaagc cagtaaagaa cattcagcag aataccggtg atcattactg ccacgaccgg
     6661 tgccgccatt ttctgtaccg gacggcccag ggattcgttg aggaagtaaa tggcaaccgc
     6721 gatagagaat ccggtataac ccgccatctt aattgctgcg aaaatcgaac cgaccagcag
     6781 cgccacttcc atcagcatat tcatggcgtt acggatgtta tccgacgcat tacgcaccga
     6841 cgggtagcgt cccagccatt tgccgatcga acgaagcagc aagacttccg ccgaaataac
     6901 cactgcgcct aataccgctg caaccatcgg attcggcgag agatagccca ccgcataaac
     6961 aaaggtaaag cccgcaactg catacacacc cgttgctaac gcggtggtgg caatcaacgg
     7021 cacaaacccc agtccgcgca taaattctgc cagagccgcc tgattaatca gcgtttgcga
     7081 ttgttccggc gttacgcctg cggaatatgc tttctccagt gtgaagatcg acacttcact
     7141 gccagcaaaa atcttcatgc tggcaacggc ggcaatcaat gctcccacga tggcgatata
     7201 gggtaagttt ttgataatcc gtgacgtgcg ttcttcaaac accgaaagcc cgctggcatc
     7261 aatgtcattt tcatcacgat gacgcaggtc gtgagttatc gcgatcccca gcagcatcac
     7321 catgccaata aagatttcga tggattcagg gttaagatgt gggaaatagc gcacgactac
     7381 cacacgggtc atcagtacca ccacggcggc gatcagactt tgcttccagc caaactggta
     7441 gaaaatcgcc accagcggga acagtgcaaa agctgaaacc accggcgagc ttaattcccc
     7501 caggctacct aatacatcca ccggcagcgc ggtcagcagc tggtttactg gcaacaggca
     7561 agtaaggatc aacacgcccc agatagcgcc aagaccaaac gccatcaggc tgtttatcgc
     7621 caggacgccg aggatatcgg taggaagaaa gagtaaccat gcgttgagca gcccggtttt
     7681 cagggtaaaa gagatcccca ccgaggccac aaaaccaatg ctcagaccaa aagcgatact
     7741 ccccgcctcg cgacggttca tatagccttc aatcagttgc ggcaggatcg ggcggatgcc
     7801 gtcatgaaaa acagccgccg agcgatgcgc cagaagcgat gtcatacccg tcaggcacgc
     7861 caccacgata atctgaatat acagatccat agtcgtgcct tttatttcag atggttaatc
     7921 agcatcggaa tcgcgtgttc gacgtgctca acggaaaggc caaacgccac ttttccttca
     7981 gcgatcattt tggcgatatg ctcgtctttc gctttaatgc ctggtttggc aatggtgcaa
     8041 cttttgttat agcctatcac cgcgatggca atcgacaatg ccgcgcccgc accggtatta
     8101 cacgcgccga tgtaataatc cagttgcccg gatttcacct tcattgccgc ttccatgtcg
     8161 ttgtgaatga aaacttcaaa acagccagga gccgtcgctt caatagtttt tttaatctgc
     8221 tcacgctgta agcctgcaac gccaatcttt ttcatgagtc tgtccttatt ggaaaaattg
     8281 agagggattt tcacgtaaca tcacatccac atcggcctga ctgaatcctg actggcgcaa
     8341 ttgcggaata aaggtggtta gtaaatagtc atagccataa ccaccgttgg cttttaaatg
     8401 ggagcggcgc gtaatatcca tcgacagcat gacgcggttc agcaacccac ggtcgcgtag
     8461 cgcatgaagc atcgcaatac gcttttcgtc cgggtagtaa ctgttcttgc cgatggtgtc
     8521 gaactgcacg tacgcgccga gatcgatcat cttcaaaatg ttgtcgaggt tgtctttcag
     8581 atcgcagtga ccaacggtga cgcgcgaaag atcaaccccg tgggcttgta gcaacgccag
     8641 ttgctccagc cccatcgtgc tgaacgacgt atgcgtggag atcgggcgtc cggtctggtt
     8701 atgcgccagc gcagcggcaa taaatacctt ctcttccagc ggcgtaatct ttccttcgct
     8761 ggtgccgatc tccgcgatga tcccggcttt cagctccgtg ccatcgatac cctgttcaat
     8821 ttcatcgacc atctcctgcg ccagttcctg cacgctgcgg gtcgccacat gttccgggaa
     8881 aaacgcgtcc tggtaataac cggtacaggc caccacgttg atccccgtct cgcgcattac
     8941 atcaagcata aattgcgcat tgcgccccat gtaacggttg gtcatctcaa tcacattacg
     9001 cacgccccgg gtcatcaggt cgttcatctc ctggcaaatg aacgcatact gatcaaggcg
     9061 gcagtccacg ttgtttttaa agccggagag atcaatatgc agatgctcat gggcgagggt
     9121 gtaacccgtc ggatcaaaac tcatagggtg tctcctgcaa accggaggga ggaaagaaaa
     9181 gagcgaccat tttgtggcgg tggcgcgcgg aaaaattcac acacggtagc ccccacatca
     9241 gaaagcgtgg tgcgcacacc gagctgcgta gcgatcatcc cttgctgata aaccagcact
     9301 ggcaccactt cgcgggtatg gtggctgtga ccaatggtcg gatcgttgcc gtgatccgcc
     9361 atcacgacca ggcaatcatc tggctgcatc gcctcaacaa gccgggcaag gttacggtca
     9421 acgacctgca aacgttcggc ataacgtgcg acgtcttctg catgaccagc gaggtcggtt
     9481 tcctgaatgt tggtgcaaat aaacgccgtc ggatgggtgt taaattcgtt gagggtgata
     9541 tccataatcc gctggctatc caccagattt tgccagctca cgccataagg attgttgacg
     9601 atatctgcca ccttacccac cagcacggtt ggcacgcctg cttcatacag tttttgtggc
     9661 acctgcactt tttcatcgac gccatagccc atatgcacga cctggaaacc gttgtcataa
     9721 gcgccagaac gcggcgcatt gataccaata aagcgccctt ctttgctttc tgcggcatcg
     9781 agaatgcgtt gactgtcggt taacaggcca ccaaatgtaa tgacccgacc gacctgtacc
     9841 tgctcacgca cgatacgacc aattttgatt gcgtcgtcaa aagagatcac agagagattg
     9901 gcggtaatgt tatagacctg gcctaaatcc gcctcgagat tatcgccaat cgcaaccgcc
     9961 tgattgaccc acagaaattg cagatcatcg ccacggcgct ccacctgcca gccagcggaa
    10021 actaatgcct gctcaacacg gtcaatcaca tcgcgaaaag gcatccgcag cggcggtaac
    10081 gggcgcgtgc ctaaaatttc ctgatgcccc ataaaggtat cgccaccttc atgttgcagc
    10141 tctgccacgc cccaggttgc ggaatctgac ggctgcatat cgcctggcgc ataacccaat
    10201 gcgttgatta gccccagctt ctccagcgtt ggtagctgca aatgcggcaa ctggctcagg
    10261 atgtgaccac atgtattcgc tcccgcatct tgcggacgca ccagcgtgac atctttcatt
    10321 gcccctacgc caaagctatc aatcactaac accacaaatc gcgccattac gcccccagag
    10381 agtttccaag actgtcataa cgaccgacga tttccggttc gccacgatga ataccggaca
    10441 ccagcaccac atcgctacgg gtgacaaaaa tctgcgtgcg aaaacagagc accactgcac
    10501 tgcttaccgg aaactcgcct gccagcggca gggtgtagtc gatactgctg tcatccacag
    10561 ttttgagatt ggtttcagta atcttttgat tttctggcgt aaacaccaac gcatgttgcg
    10621 catgaccacg acgatagtaa ccgccgccgt agcagtagct gtcgccacgg aaatgatggg
    10681 agatttcact taaccagagc atcgcgatac gttcaggctg atcgccctgc tggtttgccg
    10741 gaatagtgcc cgtcagcgca tgaccgggtt cggcatgagt cacaccgtat tgcgccagta
    10801 atggcagcga agtgcagctg gtcgctgaag gcgcgttcag ttgctcaagt gcaataccag
    10861 atttcgccag ttgatcccgt gcctgtatca gcgtgtgaag attcggtgtc ggcaaaactt
    10921 ttccgacagc ctcatcccaa agcaggcaag ggaaatgggt aagtccggct aaatgcagcc
    10981 ctggcagatt ctggatttcg gcgacaatct ccggcaacac cttgagggca aaaccgctct
    11041 cctggcccgg ataaagaaaa tcatcgtcgc tataaacttt aagcagcaca gactggattc
    11101 gcccggcctt caccgccgcc gcagaaactt cccgcgcttt gtcgagagta aacacggtga
    11161 tgacgtcggt gccctgttca acggcgtcag caacctgatg acaagggatt tgtaccagat
    11221 gcccctgatg cgccacaggc aaaccagcgc ggcgcatgac tcgcgcctct ttgtaatcca
    11281 ccgccacaat gccgctgtag cctaatgcca gcaatttttc cgccagccac ggattacgac
    11341 caaactgctt ggtcatcaga tacagttcaa tgccgtaaag ccgcgccgtc tcaatcagcc
    11401 gcttaccgtt ttccagtatc tgatccacgt cgatcaccca gctgtccggg gcgatcttgc
    11461 cctgctgcca caggcttagt gcggcggaaa tcagcgccgg gttctggcgt ttcaatgctt
    11521 ctacaaacat cttgttgcct cgtttctgtt ccttgaatta aatattcatt tttttgaata
    11581 tttaggttgt gcgacgtgga tttgtcggga gcttcaaacc tcttcgttag cagccatcca
    11641 taatccataa aggttggcca gcaaatagcc ttcttcacac gggttaactt ccagtgcgaa
    11701 ttccttcaac aacacctgat gcaattgcac aacggcttgc cagtggctgg attgcgccag
    11761 ttctgccagc aactcgttat ccagcggctc tatttcttca ccacggcgac tgcgcatcag
    11821 tgcactcgcc atatgtgtca tcgccatcgt tccttgctca ctgcgcaccg gcagatggca
    11881 ctctgtttcc agtacgttga cgacctgcat catgcctttg cagatgtcct tatcaataac
    11941 gcctgcctcg caaagcaggt tgagtctggt ttccatatca gatgcctttc gtttaataac
    12001 tcggttcctg ttccccactc actacccgtt gttgatgggc gagcagggcg tgtttatcta
    12061 caacggcacg cagcagttgt tgcattgggt aatcatcgac tcgcgtcagg accacggctt
    12121 cggtggcctg taaaaatcgc ggatcgtctg tgagcggcgt cgcctctaat cccagcatgg
    12181 tcagttcgtt ttccgccacc acgttccaga tcaccgcatc gacatcgcct ttaacaatgc
    12241 gttgtaaact ctcgtgataa gagagatcga ctcgttccac atcactaccg ccaaaaaaaa
    12301 catcggtcat gattttctga tccgccgaac ggttatccag ccccacgcgc ttcacgtttg
    12361 cggactcgcc tttacggcaa atcaactggt gctcgccaac gtaggtgtgc ggccccaact
    12421 ccagcgcgag gcataagcct ttttgcgtga gataactttc cgccgctagt cgcgaaacca
    12481 ccgccatgtc atacacgcca ttaagcagac actccacgcg aatatccgcg ccacgcatgt
    12541 gcgcatagta aaaaggaatg ccatcaaact gggctttcaa tccgctcgcc aggccttcgt
    12601 acaaacgggt atagggcaag ggcattgcac ataccacgtt gttgatatcc acatgagtca
    12661 gcaatgcttt gttatccatc tcgaccagat aactgccatt gcgcccacgg cgttcaatcc
    12721 gtatcgctcc gcttgattcc agcgttttca acgcggcctg cgtcaggcca acggatgaac
    12781 ggcattcatt tgccagctca tctatggttt tcaatcgatt accgcacttt tcacccaaca
    12841 aataacgggc cagcgtcgtg atgacgacgc cttctttttt gataaacgtt cgacgcataa
    12901 taaattttca gtaaattgaa tatttatatc ttcaggaatt tgaagataag gcgcaacagc
    12961 gagatgtgga aacggcgagg cacttcacat tttttcggat tattgcaaat gaggataaaa
    13021 aaaccgggtt tccccggttt cagagtgatg ataaaagcaa aattgcctga tgcgctacgc
    13081 ttatcaggcc tacatttcct tgcaatatgt gcattacttt gtaggccgga taaggcgttc
    13141 acgccgcatc cggcatgaac aaagcgcaat ttgccagcaa tagtgaatta cggcttcgcc
    13201 acaaaaccaa tcgcttcgta caccgctttt agcgtacggg aagcgtgcgc gctggctttt
    13261 tccgcgccat ctttcatcac ctgttgcagg aaggcttcat cgttgcggaa acggtgatag
    13321 cgttcctgca attcagtcag cataccggaa acggcatcag ccacttcacc tttcagatga
    13381 ccatacatct tgccttcgaa ctgtttttcc agttctggga tgctctggcc cgttaccgct
    13441 gaaaggatat ccaacaggtt ggaaacgccc gctttgttct gcacatcgta gcgaactacc
    13501 ggcggctcgt cggagtcagt gaccgcacgt ttgattttct tcactaccga tttcggatct
    13561 tccagcaggc cgataacgtt attgcgatta tcgtcagact tggacatctt cttggtcggc
    13621 tccagcagcg acattacgcg cgcgccagat ttcggaataa acggctccgg caccttaaag
    13681 atctcgccat acagcgcgtt gaaacgctgg gcaatatcgc ggctcagttc gaggtgctgt
    13741 ttctggtctt cacccaccgg taccagatta gtttgataca gcaggatgtc cgctgccatc
    13801 agcaccggat agtcaaacag accagcgttg atgttctcgg cataacgcgc agatttatct
    13861 ttaaactgcg tcatgcgact cagttcgccg aagtaggtat agcagttcag tgcccagcct
    13921 aactgtgcat gttccggcac gtgggactga acaaaaatgg tgcttttctc aggatcgata
    13981 ccacaagcca gatacaaggc cagcgtatcc agcgtcgctt tacgcagctt ctgtgcatcc
    14041 tggcgcacgg tgatcgcgtg ttggtcaacg atacagtaaa tgcaatggta gtcatcctgc
    14101 atgtttaccc actgacgcag cgcacccatg tagttaccaa tggtcaattc acctgagggc
    14161 tgtgcgccac taaaaacgat gggcttagtc atttttcgat tcctgatttt cgctatgcgg
    14221 aagccctaat gcgggcagaa ggtcatttat agactgataa attacatcag gctggctgag
    14281 atcgatagcc tcgccgtagt tatatccgta ggttaagcca actgatgggc aacctgccgc
    14341 ttttgccgcc tgaatatcat tgcgtgagtc gccgacaaac agcatctgtt gtggggcaat
    14401 tcccatccgc tcagccacca gtaacagcgg gtccggatgc ggttttttgt tttgcacatc
    14461 atcaccacca atcaccacgc tgaagtattt ggcgatatct aaggcttcga gcagcggcgc
    14521 gacgaacggc gtcggtttgt tggtgaccag gcctagcggc aggcctttag cctgcaacgc
    14581 gcccaacgta tcggcaacgt gcgggaacaa aaacgtcccc tcttcggcaa cctcgccata
    14641 gtagcgatcg aacagtttac gcagaatacg tacctgttct tctgccggaa tgtcgtcatc
    14701 aacgggcggt ttacccattg ttttacgctg agtcgcacgt tcctgacgcg cccaggtcaa
    14761 tgcgcgctcc atcagaacat ctgcgccgtt accaatccag gtaataacgc gttcttcacc
    14821 tgcgacgggc aactccagcg catacagcgc catatctacc gcagcagcaa gaccaggagc
    14881 actgtcgacc agcgtaccat caagatcaaa agcgacgccg cgaatatctt caaacttatt
    14941 catgacttac ctttgccagt tcactgcgca tttcatcaat gacttttttg tagtctggct
    15001 ggtcgaagat tgccgaaccg gcgacgaaca tatccgcgcc cgccgcagcg atttcgccaa
    15061 tgttgttcac cttcacgcca ccgtccactt ctagtcgaat gtcaaagcca gactcgtcga
    15121 tacggcgacg tacttcgcgc agtttatcca gtgtttgagg aatgaaagac tgaccgccga
    15181 aaccagggtt gacggacatc agcaggatca catccagctt atccatcacg taatccagat
    15241 agctcagagg tgtcgccggg ttaaatacca gacccgcttt acagccattt tctttaatca
    15301 gttgcagcgt gcggtcaaca tgctcggagg cttctggatg aaaggtaatg atgctggcac
    15361 cagcggcagc gaaatcaggc acaatgcgat cgacgggttt caccatcagg tgtacgtcga
    15421 taggggcggt aatgccatag ttacgcaagg atttcagcac cattggccca atcgtcagat
    15481 tgggaacata gtggttatcc atgacgtcaa aatgcacgac atcagcgcca gctgccaggg
    15541 cttttgcggt atcttcaccc aggcgggcaa aatcagccga cagaattgag ggggcaatca
    15601 aatactgttt catccgcttc tccttgagaa ttattttttc gcgggtgaaa cgactcctgg
    15661 tttgtacaaa gccagcagtt cgtccacctt tttacgtgtg ccgccgttgc tgcttatact
    15721 gcgtcgaact ttgacgacat gcaattttgc gcgctgatac cactcacgcg ttaacatcgt
    15781 atcgtgattg gagatcagca ctggaatatg gcgctcaacc agaccttcgg cgatctccgc
    15841 cagatgcgct tgttgttcaa gcgtaaaact gtttgtgtga tacgccgtaa agttggcggt
    15901 cgcagacagc ggtgcataag gcggatcgca atagacgacg gatgcatcat ctgcgcgcgc
    15961 catgctatcg gcgtaagact cacaatagaa aaaggcattc tgcgcttttt cagcgaagtg
    16021 atacaactct gcttccggga aatagggttt tttgtagcgg ccgaacggca cgttaaactc
    16081 accgcgcaga ttgtaacgac acaggccgtt gtaaccgtag cggttcaaat ataaaaacag
    16141 taccgcccga cggaacggat cctggctttt gttgaactct tcgcggaact gatagtaaac
    16201 ctcggcgcaa tttgtttcgg gaacaaacag ctcgcgtgcg gcctgtacgt actcatcagt
    16261 acgcatcttc acaatgttat agagactgat caggtcgcta ttgatatcgg caaggatata
    16321 acgagaaaag tcggtgttga gaaacaccga cccggcacct acaaaaggct caaccagaca
    16381 ttcgcccttg ggcaaatgcc gtttaatatc atcaagcagg ggatacttgc cccctgccca
    16441 cttcaaaaaa gcgcgatttt tcttcatgct gactaactaa ttacaccttc tccggctgtg
    16501 gagaaagctc cgacagcatc cagcgcttca ggcaactccc gcaacgataa accattgcgg
    16561 gagataacct tgattacttc agatcggcct gtacctgacg cagcggtttc gcccacgggt
    16621 ttttggcctg gacatctgct ggcaatgtag ataccgcttt tttcgcctct tctttcgaag
    16681 cgtacacgcc agaaaccagg acataccacg gctgaccatt acgcgtcgtt tcatagacaa
    16741 cgtagttttt cagattctct ttcttcgccc aaccgttcag gttgtcgtag ttagaggaac
    16801 tgctcagctg cagagtgtaa tggctggacg gtgccgattt caacgaacca acattacctg
    16861 cggtcttcgc cccagcagcg ggtgttgctg tggtttgcgc cggggatgcc gtctgtactg
    16921 gagccgtagt cgccgtctct tttggtgctg gcgtagaagt cgcagccggt gccttcgtgc
    16981 tcgccacagg ggcagctggt tcagtacgct tcggcgtctg tgctaccggc ttcggctccg
    17041 ttttcacggt tgcttgcggt tttttcggtt caatcaccgc ctgctgacga gctgggcgcg
    17101 tagtggacgg acgttcagcg gtttgcgttt tcgccgtgtc acgcgatgca ttgccattgc
    17161 gaacaggcgc aaccgttgcg ggttcagtcg gcaacgtgga attgaccgcc acattgttca
    17221 gctgttgctg attttgtggc tgggtcagcg cattgttcag gtcaccctgc acttcaacac
    17281 gttgttgacc atccgttgcc accggggttt gcccttgagt cggcgtagaa gagatcggtg
    17341 gcagagaaac atcctgctga gtattttccg cagacgtggt tcccggcgct ggctgcacgc
    17401 cattcgcctg atcggtcgca ttgccagcaa gatcaatact cttctcgcca gacgcggttt
    17461 gatcgctgga agtggtcgag ggggctttta gcgcagaacc gataccgatg atcaacagca
    17521 gtagaaccag aatgccgacg cccatcatca tatactgacg agaagcgggt ttactggctg
    17581 cttttttgcg cttacgcgga cgacgctcta cgcgctcttc atccacggtt tcatcttcgg
    17641 attcgtcaat ttcttcttcg atttccggtt cctcattgcg ctctttttgc gcacgagtcg
    17701 gacggcgatc gtcagtgtca tcaagttcaa tatcatcaaa attgatctgc ggttcgccac
    17761 gttcagtacg ctcagaacgt tcagaagatt gacgagaacg accagtacga cgatcgctgg
    17821 gatcgggttt cagctcgtct tctggtttga attcatccat ttaacacccc actaaaaggt
    17881 taatgcttac cacgttgcaa ttaacctgaa gctaatagac cgcttgataa gcggcctgac
    17941 ctttcttgtt gttacgctga ttgacaatcg gcaatggcgt taagaacaag ctcgtgcgaa
    18001 acgccgctgc gaacttcact cttaccaatt gccaacggaa gaattaagcg catctctccc
    18061 gcaaggactt tcttgtcacg cagcatatgc ggtaaatacg cctgcgcgga catttcgcgc
    18121 ggcccattga ccggtaaccc agcccgcttg agcagggtta taatacgctg cgtttcggca
    18181 gaactaaact gcccgagacg ttccgacgtc cgcgccgcca tcaccatacc cgcagcgacc
    18241 gcttcaccat gtaaccaatt gccatacccc atttcagctt caatggcatg accaaaggtg
    18301 tgtcccagat tcagtaaagc acgtaacccg gtttcgcgct cgtcggcggc gacaacttct
    18361 gccttcagtt cacaacaacg gcgaatacag tacgccattg ccggaccgtc cagacgcaac
    18421 aacgcatcca gattctcttc cagccagtta aaaaacgcac cgtcaagaat aatgccgtat
    18481 ttgatgactt ctgccagccc cgacgctaac tcacgcgggg gaagcgtttt cagacagtcg
    18541 agatccacca ccactgaagc aggttggtag aacgcgccaa tcatgttttt accgagggga
    18601 tggttgaccg cagttttgcc gccaacggag gaatcgacct gcgacagtaa cgtcgtcggg
    18661 acttgaatga aacggacacc gcgctgataa ctcgccgccg cgaagccggt cagatcgccc
    18721 actacgccgc cgccaagcgc caccagcgta gtatcgcgac catgcggttt ttgtaacaac
    18781 gccgtaaaga cggtatcgag tacagccagg cttttatact gctcgccgtc agggaggata
    18841 acgctatcga cgttaacacc cgcctgttca agtacgccgc ggaccttatc gagatacaga
    18901 ggagccaggg tttcgttggt gaccaacatg acctgctcgc ccgatttcag cggtaagaat
    18961 gaagctggtt cattaaacaa accagatgcg atggtaattg ggtaactacg ttccccgaga
    19021 gtaacgacaa tcctctccat aacgcgacat ccaccttaat tactgtaccc gcagacgagt
    19081 gtatataaag ccagaattag ttgctttcca gcatgtgaat aatctggttt gcaaccactt
    19141 tagcgctttg atcatcagta cgaatggtca cgtcggcaat ctcttcatac agcggattgc
    19201 gttcattggc caacgcttcc agaacttcac gcggcggtgt ttcaacgtgc agcaacgggc
    19261 gttttttatc acgctgcgtg cgtgcaagtt gcttttcgat ggtcgtttca agataaacga
    19321 caacgccacg agcggaaaga cggttacgcg tttcacggga tttcacagag ccgccgccag
    19381 tagccagcac aataccctgt ttctcggtca actcattgat gaccttttct tcgcgatcgc
    19441 ggaagccttc ttcgccttct aaatcgaaaa cccagcccac atcagctccg gttcgtttct
    19501 caatctcttg atcggaatcg taaaattcca tattgagttg ttgagctaac tggcgcccaa
    19561 tagtgctttt tccggcaccc ataggcccaa ccagaaagat attgcgtttc tctgccattt
    19621 tttcggtact actaagacta ttcgttaatg ataaacccgc ttcgctcaga gagcgccgca
    19681 ggacatgaac tgaaacctca taagatattg cgagagtcag actgaaaatt atctcaatac
    19741 tccagcgggt ttggcaactg aataaatcac ccatccctct gcatatctgg tcgctgcaag
    19801 cgcgctgcct tgctaccacc gctctggcga taaatcaccg ggtaagatta gcgtaaaaaa
    19861 gacagcaaaa tgccgcctga atgataaatc atcatcatgg aacgcaggca gcgaagagca
    19921 ccaactctca aatcggtact ccttgtatgc taaatacctg cgcgcgtcaa atagatgaaa
    19981 cacgttcagc gtaaaaacat taccgctttt acggctgttt actcactgga aaccagtcgt
    20041 ggcgtgataa acaccactaa ctcgcgtcgt tcatcttctt ttccgtcatg acgaaataat
    20101 tgcccgaacc agggaatgtc gccaagcaac ggtacgctat cctgacccga tttattttta
    20161 cgggtaaaaa tgccgcccag cgccaacgtt tctccgcttt tgacctcgac ctgcgtttcg
    20221 atctcctgct tatcaatcgc cagcacttcg ccatcggcct gctgtagcac ctgccccgga
    20281 acgttctggc tgatgtgtaa tttcagccgg atgcgacctt tttgtaacac cgtgggcgtg
    20341 acctccatcc ccaggacggc ctctttaaat tccaccgacg tcgcgccact ttccccgctg
    20401 gaaacctgat atggaatttc gctcccctgt ttaatgctgg caggctgaag atgtgaggcc
    20461 agcagacgcg gactggcgat aatatccagc tgctgttttt gttcgagcgc ggaaagctca
    20521 agatccagca agcgtccgtt gatgcgccca atgttaaaac cgacatgcgt tgtcgccgtc
    20581 gctacggaga ggtcgctacc aagcgtggtg acttgcccaa cgccaccagc gtgttgcgca
    20641 tcggccagcg tccatttcac gcctaactca cgcaaacttt tttcattaat ggtgacaata
    20701 tgcgccgaca gctcaacctg cccgaccggc agatccattt gcgctaccca ctgttcaagc
    20761 gcgcttaacg ccgttttgtt atctcgtagc aaaaggcgat tggtgcgttt atcgacggtc
    20821 atactccctt tggcactcag tagcttctcc cccgctttcg ccagttctcc cgcgtcggcg
    20881 tattgcaggg ttatactgcg attttccagc ggcagatttg cctgcgcccg cgcctgctcc
    20941 gcctcctggc gggcgatatt gttattctgc caggcaatgg aatgcactga gagaatgttg
    21001 ccttcctgcc gcgttatcag tccggcgctt ttcactacag tttgtagtgc ctgcttccag
    21061 ggaacatctg ttagatgtaa cgacaccgta ccgctgacgt ctggcgacac gaccaggttc
    21121 aacttctcct gttcagccag cgcctgcaac acctgagcta ccggaacgtc atccaccatc
    21181 agcgtcactt tttgcggctt tgccgcctgt acgccgggta tcagcatcaa cagtagtgcg
    21241 gctatccatt gcttcatttg tatctccttg ccgttgccac aaccattgtg gcggttcgca
    21301 gtttgtcccg gtacccagcg ttagtacgtc tggcgtcagc tgtaaaattg tccagccgtt
    21361 ttccagcaca tcgttttgct gcacccgtcg ccatttcttt tgcccgtctt ttattacacc
    21421 gatgatgcgc tcgcctcgcc ctaccatccc ctgatagcgc cactggctaa gttcgctaat
    21481 ccggcataga tcttccggcg gtttaaaagg gtcacgcata ccggttaaaa ggcacaatgc
    21541 aatacctgcc aacaaccagc gtttaaccct catgcggcgt ctccagttgt agcgtgaaca
    21601 aaagatcatc accttccacg cttaacgaaa aacggctcac gctgacgttg cgctctgcca
    21661 gccgtgtaaa tgccgacggc actgcttccc acagcgtttt caacgccaac tcgcctccct
    21721 gcgcggatgg atgccaggaa accagttgcg cgccggataa ctgaaaatcc agtggcgaaa
    21781 agggcagcgt tttttcctcg ctgaagggag tggtgtctac caggcgatac agtgcggccc
    21841 actgctggtg atgacttgcc cgtagtcgaa ttaatgcgtc gcgctcttca tggtgtgtcg
    21901 atgacagaaa aatgagcgta actaacatca gcaaccagaa tgcccagcaa agctggcgga
    21961 ggcggggtga tgtggcgaac caccagtcaa agaacatgtt catcgctaac cttccttgtt
    22021 aactgatact caaattgcca gcgtccctgc gcatcctgct gcgtggctcc ccgctgattg
    22081 agatgaaaag atgcatcctg gcggagtgac gtttctagtg cgtttaacgc ggtaatgctt
    22141 gttgtcagcc ccttgatctc cagcgttccc tgctgccagc ttatcgttgt cagccaggcg
    22201 tgctcgggta aaagcgccgc cagtgcttcc agcgcagatt gccagtcgcg ggtaaattgt
    22261 cgctggcgct gccgttgcga acgctgttcg cgtaactgct gttgctccag caaacgtggc
    22321 ttcgttatct gtaagctgcg ggcgagttgt tgttccgcct gaagcaaaac tgcgtctatg
    22381 cgcgcttcgg cgctgcctgt cagacgcagt attagcgtta tcccgacggc cagcagcaga
    22441 ggcgcaacga acatcagcaa ccagaaacgc agaaaagcgg tccggcgttg ctgtcgccag
    22501 ggcaaaaaat taattggcgg gttcatcagt acgccttccc aagcgccagc cccagcgcga
    22561 tggcaaagtc tccacctggc ggcggtagcg gcggctgacg aacagaaacg gcctcccagg
    22621 gatcaaatcc gccttcgcca catatcgcga cgctttcggg atcaacggat aacgctgccg
    22681 ccagctcctt cgcgctagtc atccccaccg ccagtttgcg cccccagcta tagcgcgtcg
    22741 cccacagcca ctgttcgtta tcacgccagg ccagacattg ctgatgagaa ggtaaaaaag
    22801 gcaggaatcg ctgtaatgca ctggcatccg gggtgatcgc gctcacatga acacgcaacc
    22861 tttctgccag agtaagcagc gttgccagct ctttgctttg cgcggcagtc acgttatagg
    22921 cgggactgag tgagtcttcg ctgtaatcga agcgcaggga gtccggatcc atatccagct
    22981 cgcgggccat cgtccctgac agccaggccg tttgctcccg ctcaccaagg gacatcgacg
    23041 ggcgcggaaa tgaccgctgt aatgtgcgac tggcgggaaa cgccaacata atgtgatgac
    23101 gctgcggcag ttcgcgactc cacggtaaca acgttttagc cagctgctgc gcatcaacaa
    23161 tccgcccatc tttgataatg tcgttctcca gcggcaaccg ccaccagcgt tgcaaaaagc
    23221 attcttttgc gccccgcacg atcgcaaccg ctaccgcttc ttgctgttgt aaatgcaaac
    23281 caatttgcca gatcttaaat gccattgtga tgatctcctt atcacccgtc actctgacgg
    23341 gtatatcaat gcgtctggct tgcctttata ctaccgcgcg tttgtttata aactgcccaa
    23401 atgaaactaa atgggaaatt tccagtgaag ttcgtaaagt attttttgat ccttgcagtc
    23461 tgttgcattc tgctgggagc aggctcgatt tatggcctat accgctacat cgagccacaa
    23521 ctgccggatg tggcgacatt aaaagatgtt cgcctgcaaa ttccgatgca gatttacagc
    23581 gccgatggcg agctgattgc tcaatacggt gagaaacgtc gtattccggt tacgttggat
    23641 caaatcccac cggagatggt gaaagccttt atcgcgacag aagacagccg cttctacgag
    23701 catcacggcg ttgacccggt ggggatcttc cgtgcagcaa gcgtggcgct gttctccggt
    23761 cacgcgtcac aaggggcaag taccattacc cagcagctgg cgagaaactt cttcctcagt
    23821 ccagaacgca cgctgatgcg taagattaag gaagtcttcc tcgcgattcg cattgaacag
    23881 ctgctgacga aagacgagat cctcgagctt tatctgaaca agatttacct tggttaccgc
    23941 gcctatggtg tcggtgctgc ggcacaagtc tatttcggaa aaacggtcga ccaactgacg
    24001 ctgaacgaaa tggcggtgat agccgggctg ccgaaagcgc cttccacctt caacccgctc
    24061 tactcgatgg atcgtgccgt cgcgcggcgt aacgtcgtgc tgtcgcggat gctggatgaa
    24121 gggtatatca cccaacaaca gttcgatcag acacgcactg aggcgattaa cgctaactat
    24181 cacgcgccgg agattgcttt ctctgcgccg tacctgagcg aaatggtgcg ccaggagatg
    24241 tataaccgtt atggcgaaag tgcctatgaa gacggttatc gcatttacac caccatcacc
    24301 cgcaaagtgc agcaggccgc gcagcaggcg gtacgtaata acgtgctgga ctacgacatg
    24361 cgccacggct atcgcggccc ggcaaatgtg ctgtggaaag tgggcgagtc ggcgtgggat
    24421 aacaacaaga ttaccgatac gctgaaggcg ctgccaacct atggtccgct gctgcctgcc
    24481 gcagtcacca gcgccaatcc tcagcaagcg acggcgatgc tggcggacgg gtcgaccgtc
    24541 gcattgagta tggaaggcgt tcgctgggcg cgtccttacc gttcggatac tcagcaagga
    24601 ccgacgccgc gtaaagtgac cgatgttctg caaacgggtc agcaaatctg ggttcgtcag
    24661 gttggcgatg catggtggct ggcacaagtg ccggaagtga actcggcgct ggtgtcgatc
    24721 aatccgcaaa acggtgccgt tatggcgctg gtcggtggct ttgatttcaa tcagagcaag
    24781 tttaaccgcg ccacccaggc actgcgtcag gtgggttcca acatcaaacc gttcctctac
    24841 accgcggcga tggataaagg tctgacgctg gcaagtatgt tgaacgatgt gccaatttct
    24901 cgctgggatg caagtgccgg ttctgactgg cagccgaaga actcaccacc gcagtatgct
    24961 ggtccaattc gcttacgtca ggggctgggt cagtcgaaaa acgtggtgat ggtacgcgca
    25021 atgcgggcga tgggcgtcga ctacgctgca gaatatctgc aacgcttcgg cttcccggca
    25081 caaaacattg tccacaccga atcgctggcg ctgggttcag cgtccttcac cccaatgcag
    25141 gtggcgcgcg gctacgcggt catggcgaac ggcggcttcc tggtggaccc gtggtttatc
    25201 agcaaaattg aaaacgatca gggcggcgtg attttcgaag cgaaaccgaa agtagcctgc
    25261 ccggaatgcg atattccggt gatttacggt gatacgcaga aatcgaacgt gctggaaaat
    25321 aacgatgttg aagatgtcgc tatctcccgc gagcagcaga atgtttctgt accaatgccg
    25381 cagctggagc aggcaaatca ggcgttagtg gcgaagactg gcgcgcagga gtacgcaccg
    25441 cacgtcatca acactccgct ggcattcctg attaagagtg ctttgaacac caatatcttt
    25501 ggtgagccag gctggcaggg tactggctgg cgtgcaggtc gtgatttgca gcgtcgcgat
    25561 atcggcggga aaaccgggac cactaacagt tcgaaagatg cgtggttctc gggttacggt
    25621 ccgggcgttg tgacctcggt ctggattggc tttgatgatc accgtcgtaa tctcggtcat
    25681 acaacggctt ccggagcgat taaagatcag atctcaggtt acgaaggcgg tgccaagagt
    25741 gcccagcctg catgggacgc ttatatgaaa gccgttcttg aaggtgtgcc ggagcagccg
    25801 ctgacgccgc caccgggtat tgtgacggtg aatatcgatc gcagcaccgg gcagttagct
    25861 aatggtggca acagccgcga agagtatttc atcgaaggta cgcagccgac acaacaggca
    25921 gtgcacgagg tgggaacgac cattatcgat aatggcgagg cacaggaatt gttctgatta
    25981 aaaaggcgct tcggcgcctt ttcagtttgc tgacaaagtg cacttgttta tgccggatac
    26041 ggcgtgaacg cgttatccgg ctaacaaaat cgtgaaaact caataaattg cagaaacccc
    26101 ataagcctga taaacattgt gcatcaggca aacttcacgc atttacactc gcccctgccc
    26161 tttcaaccat tcgcgcacga ggaacagcgc actgacattg cgcgcttcat tgaagtcagg
    26221 gtcttccagc aaatccatca tatgcgccag cggccagcgc acctgtggta gcggctctgg
    26281 ctcatcgcct tccagtgatt ccgggtagag atcttgtgct accacgatat tcattttgct
    26341 ggaaaagtaa gacggtgcca tgctgagctt cttcaaaaaa gtcagatcgt tcgctccaaa
    26401 tccaacctct tcttttagct cgcggttagc ggcttcgtag acgctttcac ccggatcaat
    26461 taatcctttc gaaaaaccta attcgtagga ttcagttccc actgcgtatt cgcggatcag
    26521 gatcaggtga tcgtccacaa tcggcacaat catcactgct tcccggttgg ttggacgcat
    26581 tcgttcataa acacgccgca cgccattgct gaactccaga tccacgctct cgacggtaaa
    26641 cagtcgggaa cgggctacag tttcaacatt cagaatggtg ggtttttgta atgatttgct
    26701 catcgtggga tctatgctgt gaaatcagcg gttattgtgc gatatcggac acgctttcgg
    26761 caatgtgaat tgcatgttat ttacatttat gtaacttaat aaataatcgt cctcaaatca
    26821 aattaaaagt caataggttg aaataactcc aggaatttgc tgatattccg ccttcagagg
    26881 gtttgctatg atcagcggtt actgtgatgt gcttaatgat gctcaagtta aactccacgc
    26941 ttgccgatag ccaaccgcag aatcatgtat tgtgtccggt gcgactgacc acgcctgaca
    27001 gactaagtaa gatggggaaa gcatgagcac cattgtgatt tttttagctg ctttgctggc
    27061 ctgctcacta cttgcgggat ggctgataaa agtgcgatcc agacggcgtc agctgccctg
    27121 gaccaacgcc ttcgcggatg cgcaaacgcg taaactcaca cctgaagaac gtagcgccgt
    27181 tgaaaattat cttgagagcc tgacgcaggt attacaggtg cctggcccaa cgggagccag
    27241 cgcggcaccg atctctctgg cgctgaatgc cgaaagcaac aacgtcatga tgctgacaca
    27301 cgctatcacg cgttacggca tctctaccga cgatccgaat aaatggcgtt actacctcga
    27361 ttcggtagaa gtccacctgc cccctttctg ggaacagtac atcaacgatg agaataccgt
    27421 tgaactgatt cataccgatt cgctgccgct ggttatttca ctcaacggtc atacgctgca
    27481 ggagtacatg caggaaactc gcagctatgc cttgcaacct gttccgtcaa cgcaggcgtc
    27541 gattcgcggg gaagagagtg agcaaatcga gctactcaat attcgcaaag aaacgcatga
    27601 agaatatgcg ctgagtcgtc cgcgcgggct gcgtgaagcg ttgctgatcg tcgcctcctt
    27661 cctgatgttc tttttctgcc tgattacccc ggatgtattt gttccgtggc tggcaggcgg
    27721 cgcgttactg ctgctgggcg caggtctgtg ggggctattc gcgcccccgg caaaatcctc
    27781 cctgcgggaa attcattgtc tgcgcggtac accccgtcgt tggggattgt ttggcgaaaa
    27841 cgatcaggaa cagatcaaca atatttcact cggtattatc gacctggtct atcccgcaca
    27901 ctggcagcca tacattgctc aggatctcgg tcaacaaacc gatatcgata tctatctcga
    27961 ccgccatgta gtgcgtcagg gacgatatct ttcactgcat gatgaagtaa aaaactttcc
    28021 gttacagcac tggctgcgca gtacgattat cgctgcgggc tcgctgctgg tgctgtttat
    28081 gctgttattc tggatcccgc tggatatgcc gctgaaattc actctctcat ggatgaaagg
    28141 cgcgcagacc attgaagcca ccagcgtaaa acaactggct gacgctggcg tgcgggtagg
    28201 cgatacattg cgtattagcg gtacgggaat gtgtaatatt cgaacttccg gaacctggag
    28261 cgcgaaaacc aattcacctt ttttaccgtt tgactgctcg cagatcatct ggaacgacgc
    28321 ccgctcattg ccattaccag aatctgaact ggtcaacaaa gcgacggcat tgactgaagc
    28381 agttaatcgc cagctgcacc ctaaaccgga agatgaatct cgcgtcagtg cctcattacg
    28441 ttcagcaatt caaaaatccg gcatggtatt gcttgatgat tttggcgaca ttgtactgaa
    28501 gacagcggat ttatgttctg ccaaagatga ctgtgtgcga ctgaaaaatg cgctggtcaa
    28561 tctcggcaac agtaaagact gggacgcgct ggtaaaacgc gccaacgccg ggaagctcga
    28621 tggcgtgaat gtgttattac gcccggtgag tgcggaatcg ctggataacc tagtggcaac
    28681 ctccaccgcg ccgtttatca cgcatgaaac ggcgcgagcg gcacaatcac taaacagtcc
    28741 ggcccccggc ggattcctga ttgtcagcga cgaaggcagc gattttgttg atcagccctg
    28801 gccttcggca tcactttacg actacccgcc gcaagaacag tggaacgctt tccagaaact
    28861 ggcacaaatg ctgatgcata cgccgtttaa cgccgagggt atcgtcacaa aaatcttcac
    28921 tgacgccaat ggtacgcagc atattggcct tcatccgatc ccggatcgtt ccggcctgtg
    28981 gcgctatctc agcaccacat tgctgctact gacgatgctg ggtagcgcca tttacaatgg
    29041 cgtacaggcc tggcgtcgtt accagcgtca tcgcactcgc atgatggaga ttcaggccta
    29101 ttatgaaagc tgcctgaacc cgcaactgat caccccttca gaaagcctta tcgaataaca
    29161 cgtttgcgcg gcaggttatg ctaccctgtc gcgcaaattg cttcactctg gagatttccc
    29221 tcatgcatat caacattgcc tggcaggacg tagataccgt tctgctggat atggacggca
    29281 cgttgctcga cctcgccttc gataactatt tctggcaaaa gctggtgcct gaaacatggg
    29341 gcgcgaaaaa cggggttacg ccacaggaag cgatggaata tatgcgccag caatatcacg
    29401 acgtacagca tacgctaaac tggtactgtc ttgattactg gagtgagcaa ctgggtctgg
    29461 atatctgtgc gatgaccacc gagatgggac cgcgtgccgt actgcgtgaa gataccattc
    29521 cgtttcttga ggcactgaaa gccagcggta agcagcgaat tttgctcacc aatgcgcatc
    29581 cgcacaacct ggcggtaaaa cttgagcata ccggtctgga cgcacacctt gatttattac
    29641 tttccaccca cacatttggt tatccgaaag aggatcagcg gttatggcat gcggtggccg
    29701 aagctacggg tctgaaagct gaaagaacgc tgtttattga tgacagcgaa gcgattctcg
    29761 atgctgccgc gcaatttggt attcgttact gcctcggcgt gactaatcct gattccggga
    29821 ttgccgagaa acagtatcaa cgccatccgt cactgaatga ctaccgccgc ctgatcccct
    29881 cgctaatgtg aaggagacgc catgaaagag aaacctgctg ttgaggttcg actggataaa
    29941 tggctatggg ctgcccgttt ttataaaacc cgcgcgctgg cccgtgaaat gattgaaggc
    30001 ggtaaggtgc attacaacgg gcagcgcagc aagccgagca aaatcgtcga gctgaatgcc
    30061 acgctcactc tgcgccaggg aaatgacgaa cgcacggtga ttgtaaaggc gattactgaa
    30121 cagcgtcgcc ccgccagcga ggcagccttg ctgtatgaag agactgcgga aagtgtagag
    30181 aaacgcgaaa aaatggcgct ggcacgtaaa cttaatgcct taaccatgcc gcacccggac
    30241 cgacgcccgg acaaaaaaga gcgccgcgac ctgttacgat ttaaacacgg cgacagtgaa
    30301 taactgtcac ctgcaagaga gatgattatg ccgcaacatg accaattaca tcgctatctg
    30361 tttgaaaact ttgccgtgcg cggcgaactg gtaaccgttt cggaaaccct gcaacagatc
    30421 cttgagaacc acgattatcc gcagcccgtt aaaaacgtgc tggcagaact gctggttgcg
    30481 accagcctgt taaccgctac gctgaagttt gatggtgata tcaccgtaca gctgcagggc
    30541 gacggtccga tgaatctggc ggttattaac ggtaacaata accagcagat gcgcggtgtg
    30601 gcgcgcgtgc agggcgaaat tccagaaaat gccgacctga aaacgctggt cggcaatggt
    30661 tacgtggtga tcaccattac cccgagcgaa ggcgaacgct atcagggcgt agttggtctg
    30721 gaaggtgata ccctggcggc ctgcctggaa gattacttta tgcgttctga acagctgccg
    30781 acgcgcctgt ttattcgcac cggcgacgta gacggcaaac cggctgcagg cggtatgttg
    30841 ttgcaggtaa tgcctgcgca aaatgcccag caggacgact ttgaccacct ggcgacgcta
    30901 accgaaacca tcaaaaccga agaactgctg accttaccgg caaacgaagt gttgtggcgt
    30961 ttgtatcacg aagaagaggt gacggtttac gatccgcagg atgtggagtt caaatgcacc
    31021 tgctcgcgtg aacgttgcgc cgatgcgctg aaaacgctgc ctgatgaaga agttgatagc
    31081 atcctggcgg aagatggcga aattgacatg cattgtgatt actgcggtaa ccactatctg
    31141 ttcaatgcga tggatattgc tgaaatccgc aacaacgcgt ctccggcaga tccgcaagtt
    31201 cattaatgag tatgtccggc agagagggct ctgccggatt ttacgactaa tacacctgat
    31261 gcgctttgtc actcattcag attcacattc agcctttcac catccactac aagatcgcgc
    31321 cacgctttag gcttcgtccc cagttttcca tccttcgcag ctgtgagtaa tttttctttc
    31381 gttatttcgt tcggaagtaa actcatatca agcgcgtccc attcttttct gtctgagtca
    31441 aagccataga caatgactct gtcatcatta aaagcaaaca ggatccgctc cgcctgacca
    31501 tcactattca gatcttgctc gaccaggacg caggcgtctt tttcaataca ggtcatcacg
    31561 ttatagcgat cctggattaa ggccgaccag aatgtcgcat caggtttaac agaaccaggg
    31621 gcaattaaca cattatcggc taatactttt tccgatacct gttgctgaag atgttgctct
    31681 ccatctaacg ccatcagcag atcccgcgcg cgtttcgggt ctttcataaa cccggcatcg
    31741 cttttcagcg actcaagcgc agcacgtcca tagcgaccgc tctgctcgag catgtagata
    31801 gttacctggt ctgacgtgtt tttgccgctc tgataacgcg ccatatggct gttcacgcta
    31861 atgcgcatac tgtccagcac cggcgaatta agaagcacca gtatcaccaa caccaataac
    31921 gaaaccgcaa ggttcacttt gccctgaaga acaacgggat tttgcccttt acgccagacg
    31981 atgctgacaa aataccccag cgaccacacc agtaacacca gcaccgccag cacgccctgc
    32041 aagcggtcga cagtccagcc gtactgagcg acccgcagcc ataacgccca ggcggcgacg
    32101 aacacataca gcggagcaac cagcaaagcg gttttaatca ggcaacgcaa cggccctgtc
    32161 cagggaagtg acgctttttg cggatcgcgg acaatagcca ttaagatcaa ttgcaaaaag
    32221 gccagcgtca acagcaaccc ggcggcggag atgtggcgag aaatcgcgct caggcccgta
    32281 aacggcaggg tgatgataaa catcagggtt agcaatgata ctaacggcag caaccccgtg
    32341 gcgattaacg tgaacaactt ttgaatagag tcgattaaac gtgactgtgt tcgcgcgagg
    32401 atcaccgcca gcgcggtaac cagacctaac gtgagataaa taaaccagtc ggttgcaaaa
    32461 aagagcgtat tgaaaaacgt gatgccaaca agtttaaaca actcactcca cagtaaaagc
    32521 accagccacg tcaagccatt ggcgagaaaa atcaccagta atataagtac gttatgccat
    32581 actgactggt aaaaatagcg atagcggcta ctgtcattgc ggatgcgaag gctttgttgt
    32641 atccacggta gcaacaacat tgccatcaac agcagatagc aaccaaaatc ccaaagcgcc
    32701 ttttcagctc tccaggggtt catgccatca gtttgccact tcagccagcc gctcatcccc
    32761 agcgtggcaa taaacactag cgccagccat ccccaaaggc gcttctgttt aaaagagatc
    32821 acggagaaga gtaaaacgga tgaaaacgcg acggtcgcag gcacgccata aacaatccaa
    32881 ctgtgatttt ttccggaaag ccaggcgatc agcaggtagc aaaccagacc ctgaagtaat
    32941 ccggtagcaa tcatccccca gcgtgttgcg ggtgaaagtt caacgttatc catgttggtt
    33001 atccagaatc aaaaggtggg ttaattatcg catccgggca gtagtatttt gcttttttca
    33061 gaaaataatc aaaaaaagtt agcgtggtga atcgatactt taccggttga atttgcatca
    33121 atttcattca ggaatgcgat tccactcaca atattcccgc catataaacc aagatttaac
    33181 cttttgagaa cattttccac acctaaaatg ctatttctgc gataatagca accgtttcgt
    33241 gacaggaatc acggagtttt ttgtcaaata tgaatttctc cagatacgta aatctatgag
    33301 ccttgtcgcg gttaacaccc ccaaaaagac tttactattc aggcaataca tattggctaa
    33361 ggagcagtga aatgcgcgtt aacaatggtt tgaccccgca agaactcgag gcttatggta
    33421 tcagtgacgt acatgatatc gtttacaacc caagctacga cctgctgtat caggaagagc
    33481 tcgatccgag cctgacaggt tatgagcgcg gggtgttaac taatctgggt gccgttgccg
    33541 tcgataccgg gatcttcacc ggtcgttcac caaaagataa gtatatcgtc cgtgacgata
    33601 ccactcgcga tactttctgg tgggcagaca aaggcaaagg taagaacgac aacaaacctc
    33661 tctctccgga aacctggcag catctgaaag gcctggtgac caggcagctt tccggcaaac
    33721 gtctgttcgt tgtcgacgct ttctgtggtg cgaacccgga tactcgtctt tccgtccgtt
    33781 tcatcaccga agtggcctgg caggcgcatt ttgtcaaaaa catgtttatt cgcccgagcg
    33841 atgaagaact ggcaggtttc aaaccagact ttatcgttat gaacggcgcg aagtgcacta
    33901 acccgcagtg gaaagaacag ggtctcaact ccgaaaactt cgtggcgttt aacctgaccg
    33961 agcgcatgca gctgattggc ggcacctggt acggcggcga aatgaagaaa gggatgttct
    34021 cgatgatgaa ctacctgctg ccgctgaaag gtatcgcttc tatgcactgc tccgccaacg
    34081 ttggtgagaa aggcgatgtt gcggtgttct tcggcctttc cggcaccggt aaaaccaccc
    34141 tttccaccga cccgaaacgt cgcctgattg gcgatgacga acacggctgg gacgatgacg
    34201 gcgtgtttaa cttcgaaggc ggctgctacg caaaaactat caagctgtcg aaagaagcgg
    34261 aacctgaaat ctacaacgct atccgtcgtg atgcgttgct ggaaaacgtc accgtgcgtg
    34321 aagatggcac tatcgacttt gatgatggtt caaaaaccga gaacacccgc gtttcttatc
    34381 cgatctatca catcgataac attgttaagc cggtttccaa agcgggccac gcaactaagg
    34441 ttatcttcct gactgctgat gctttcggcg tgttgccgcc ggtttctcgc ctgactgccg
    34501 atcaaaccca gtatcacttc ctctctggct tcaccgccaa actggccggt actgagcgtg
    34561 gcatcaccga accgacgcca accttctccg cttgcttcgg cgcggcattc ctgtcgctgc
    34621 acccgactca gtacgcagaa gtgctggtga aacgtatgca ggcggcgggc gcgcaggctt
    34681 atctggttaa cactggctgg aacggcactg gcaaacgtat ctcgattaaa gatacccgcg
    34741 ccattatcga cgccatcctc aacggttcgc tggataatgc agaaaccttc actctgccga
    34801 tgtttaacct ggcgatccca accgaactgc cgggcgtaga cacgaagatt ctcgatccgc
    34861 gtaacaccta cgcttctccg gaacagtggc aggaaaaagc cgaaaccctg gcgaaactgt
    34921 ttatcgacaa cttcgataaa tacaccgaca cccctgcggg tgccgcgctg gtagcggctg
    34981 gtccgaaact gtaatgattt gaagctggag aatatctatc cagtatctta tagaaagcaa
    35041 aacgggaggc accttcgcct cccgtttatt tacccttctt ttgtcgtgcc ctgcgcccgc
    35101 gttaccggca ctggcagcca ggcgcgaatg gaaagcccgc cccgctcgct ggtgccaagc
    35161 tccagcatcc cgttatggtt atccacgata cgctgcacaa ttgccagccc taatcccgtg
    35221 ccgctaatgg tgcgcgcact gtcgccgcgg acaaacggct ggaacaggtg cttacgttgt
    35281 tccggcgcaa ttcccggacc gtcatcttcc acctggaacc aggcgcgatt cggctccgtt
    35341 ccgctgctga ctttgatcca gccattgcca taacgggcgg cgttgaccac catattcgcc
    35401 accgcgcgtt tgatcgacag cgggtgcatt ttcacttcaa tgctgccggg gtaaagcgcg
    35461 gtttcaattt cccgctcata gccactttcg gcagcaatca cctcaccgag tactgcatta
    35521 agatccgcca tttccatcgg catctcctgc ccggtgcgca ggtagtcgat aaactgctca
    35581 atgatggcgt tgcactcttc gatatcttta ttgatcgatt ctgccagata gccatcctgc
    35641 tcgctcatca tctcagtcgc caggcgaata cgcgtcagcg gcgtgcgcaa gtcgtgactt
    35701 acccccgcca tcagcagcgt gcggtcatcc gccagttgct taacaccagc cgccatatgg
    35761 ttaaaggcac gggtaacgga acgcacctcc gaagcgccat actcacgcag cggcggcgga
    35821 ataatccctt taccaacctg caaggctgcg tgttcgagat cgaccaacgg tcggttctgg
    35881 atacgaataa acagccacgc cccgcctatc gccaatagca taatcgccag cgtatagcgg
    35941 aacagcggag agaaatcgcc ctgatgaatt tcggtcagcg gcacgcgtac ccagatattg
    36001 ggcgacagcc aggttttcag ccagacgaca ggcgaacttt tgttgacctc aacgcgcact
    36061 tccgtcgggc cgcccagttg ctgcgccatc tgatggctta agaattcata gtgttgcgcc
    36121 caacgcagac ctgcctcttc ggcagcctcg ttggagtaga gagagatccc cagctcacgg
    36181 tagatctccc gacggaaagc gggaggcaca accaactgcg tgccgtcctc cagttgcagt
    36241 ttgtcggtca tcaacatacg cacttcgtac gcgaggactt tattaaactg ctggaggctc
    36301 ggcaaaatcg cgaagttcag caccaccaga taagtcgtca ccaggctggc gaacagcaag
    36361 gtgacgatga gcaataacgt acgggcaaat gaacttcgtg gcgagaagcg caatcgcctc
    36421 atgctttaga gccgtccggt acaaagacgt agcccagacc ccagacggtc tgaatgtaac
    36481 gcggatgcgc tggatcttct tccaccatgc ggcgcagacg cgaaatctgc acgtcgatgg
    36541 agcgttccat tgcggaatat tcacgaccac gggcaaggtt catcagctta tcgcgggaga
    36601 gcggctcacg cggatggctg accagtgcct tcagtaccgc aaactcaccg ctggtgagcg
    36661 gcatcggctc gtcttcgcgg aacatttcgc gcgtaccgag gttaagtttg aacttaccga
    36721 aagcaattac cgcctcttcc tgtgacggtg cgcctggcag ttcgttcgcc tgacgacgca
    36781 gcaccgcacg gatacgggcc agcagttcac gcgggttaaa cggttttgga atgtagtcgt
    36841 cagcgccaat ctccaggcct acgatacggt ccacttcttc ccctttcgcc gtcaccataa
    36901 tgatcggcat cgggttgctc tgactacgaa gacgtcggca aatcgacaag ccatcttcac
    36961 caggtaacat taaatccagt accataagat ggaaagattc acgagtcagc aggcgatcca
    37021 tctgttctgc attagcgacg cttcgaacct ggaagccttg ttcggtgaga taacgttcca
    37081 gcagcgcacg caggcgcatg tcgtcatcga ccaccagaat cttgtagttc tcttgcattg
    37141 tttgtactcc caaaggttcg caacaatttg taagcgtgta ttcttaaaaa agctcacgtt
    37201 cgtcaccagc taaatctggt atgaatttca gcctaaattg ttacaaagca tattaaacag
    37261 cagcttaagt atacaattta ttcggcgaaa cattattgat tctgttgata tgatcacgtt
    37321 atacccaatg tgcgcattat caaacagaca aagggaatca acgagatgaa aacgcccctg
    37381 gttacccggg aagggtatga aaaactcaaa caagagctta attatctctg gcgtgaagaa
    37441 cgcccggagg tcacaaaaaa ggtgacctgg gccgcaagtc tgggcgaccg cagcgaaaat
    37501 gctgactatc agtataataa aaagcgtctg cgtgaaatcg accgtcgcgt gcgctatctc
    37561 actaaatgcc tggaaaatct caaaatcgtc gattactccc ctcagcagga aggcaaagtc
    37621 ttttttggcg cgtgggtgga gattgaaaac gacgatggcg tgactcaccg tttccgtatt
    37681 gtcggctacg atgaaatttt tggccgtaaa gattacatct ctatcgattc cccgatggcc
    37741 cgcgcattgc tgaaaaaaga agtcggcgat ctggcggtgg tgaatacccc tgccggggaa
    37801 gcgagctggt atgttaatgc tatcgagtac gtgaaaccgt aaggaagagt cttaacctcc
    37861 tgccgatggc tggcattttt gccagccagt ccgtataact atcccctgat ttttgatccg
    37921 aaaagatgaa ctcaaaccat gatgaatgat tcgttctgcc gcattattgc gggtgaaatt
    37981 caggcgcgcc cggaacaggt tgacgctgcc gttcgcctgc ttgacgaagg gaataccgtg
    38041 ccgtttatcg cacgttatcg taaggaaatc accggcggtc tggatgacac gcagctgcgt
    38101 aatctggaaa cgcgtctgag ctatctgcgc gagctggaag agagacgtca ggcgatcctc
    38161 aagtccattt ccgagcaagg caaactcacc gatgatctgg cgaaggccat caacgccacc
    38221 ctaagcaaaa ccgaactcga agacctctac ctgccctaca aacctaaacg ccgcacccgc
    38281 gggcaaatcg ccattgaagc agggcttgag ccgttggctg acctgctgtg gagcgatccg
    38341 tcacacacgc cagaagtcgc cgctgcacaa tatgttgatg ccgataaagg cgtggcagat
    38401 accaaagccg cgctggatgg cgcgcgctat atcctgatgg aacggtttgc cgaagatgcc
    38461 gcgctgctgg cgaaagtgcg tgattatctg tggaagaacg cgcatttggt ttctacggtg
    38521 gtgagcggta aagaagagga aggggcgaaa ttccgcgact atttcgatca tcacgaaccg
    38581 ttgtccacgg tgccttctca ccgcgcgctg gcgatgttcc gtgggcgtaa cgaaggcgta
    38641 cttcagcttt cgctgaatgc cgatccacag ttcgatgagc cgcccaaaga gagctattgc
    38701 gagcaaatca tcatggatca ccttggcctg cgcctgaaca atgccccggc ggatagctgg
    38761 cgcaaaggcg tggtgagctg gacgtggcgc atcaaggtgc tgatgcatct ggaaaccgaa
    38821 ctgatgggca ccgtgcgcga acgtgcggaa gatgaagcaa tcaacgtctt tgcccgtaac
    38881 ctgcacgatc tgctgatggc ggcccctgcc ggactgcgtg caacgatggg cctcgatccg
    38941 ggtctgcgta ctggggtaaa agtggcggtg gtcgatgcca ctggcaaact ggtggcgacc
    39001 gacaccattt acccgcacac cggacaggcc gcaaaagcag cgatgaccgt tgctgcgctg
    39061 tgtgaaaaac ataacgttga actggtagcg atcggtaacg gtacagcttc ccgcgaaact
    39121 gagcgtttct atctcgatgt gcagaagcag ttcccgaaag tgaccgcgca gaaagtaatc
    39181 gtcagcgaag caggcgcgtc ggtttactcg gcttccgagc tggctgcaca ggagttcccg
    39241 gatctcgacg tttcgctgcg tggcgcggtg tctatcgccc gccgtttgca ggatccgctg
    39301 gcggagctgg tgaaaatcga tccgaaatct atcggcgtag gtcagtatca gcatgacgtc
    39361 agccagacgc aactggcccg caaactggac gcagtagtag aagactgcgt aaacgccgtt
    39421 ggcgtcgatc tcaacactgc ttctgttccg ctgttaaccc gcgtggcggg cctgacgcgc
    39481 atgatggcgc aaaacatcgt tgcctggcgc gatgagaacg gtcagttcca gaaccgtcag
    39541 caactgttaa aagtgagccg tctggggccg aaagccttcg agcagtgcgc gggcttcttg
    39601 cgcattaacc acggtgataa cccgctggac gcgtctaccg ttcacccgga agcctatccg
    39661 gtggtggaac gcattctggc agcaacacag caggcactga aagatctgat gggtaacagc
    39721 agcgaactgc gtaacctgaa agcgtctgac tttactgatg agaaattcgg tgtgccgacg
    39781 gtaaccgaca tcatcaaaga gctggaaaaa ccgggtcgcg atccgcgtcc ggaatttaaa
    39841 accgctcagt ttgccgatgg cgtcgagaca atgaacgacc tgcaaccggg tatgatcctc
    39901 gaaggcgcag tgaccaacgt caccaacttt ggcgcgtttg tcgatattgg cgtgcatcag
    39961 gacggcctgg ttcacatctc ttcattgtcg aacaagtttg tggaagatcc gcataccgtg
    40021 gtgaaagcgg gcgacattgt gaaggtgaaa gtgctggaag tggatcttca gcgtaaacgt
    40081 atcgccctga ctatgcgcct ggatgagcag cctggcgaaa ccaacgctcg tcgcggcggc
    40141 ggtaatgaac gcccgcaaaa caaccgcccg gcagccaaac cacgcggtcg tgaagcgcag
    40201 cctgccggta atagcgcgat gatggatgcg ctggcggcgg caatgggcaa aaaacgttaa
    40261 acgcccgtac tggcctacgg ttcgaatttg cacgaaatcg tagggcagat aaggcgttca
    40321 cgccgcatct ggcaacgaac gccttgcctg acataaaagt gccggagaat atctccggca
    40381 tttttattcc acagccaaac tcataatata ttccggcaat atttatcatt tcattaacaa
    40441 ctgaaacctt aattaaacat tagccagtcc gggtaattca ctattcgaat tatattttcg
    40501 ctgcgatata accttgagcc acatcaacat tgagtcagat tattattcaa accaacattc
    40561 gcacacattt taagtattgc tgatagaaac cattctcatt atcattgtgt tgttgattat
    40621 ttaatctctc ctttgttggc aaatcatctg gtctcatgtc gctgtcaaac gccccatgag
    40681 gtagttatcc agttaatgag aaacaagtag gcacctatgc aatacactcc agatactgcg
    40741 tggaaaatca ctggcttttc ccgtgaaatc agcccggcat atcgccaaaa actgctttct
    40801 cttggcatgt tacctggctc ctcttttaat gtggtgcgcg tcgctccact cggcgacccc
    40861 attcatatcg aaacccgtcg tgtgagcctg gtattacgca aaaaagatct ggccttatta
    40921 gaagtggaag cggtttcctg ttaatacggt gataacaaca atgaaaaaat taaccattgg
    40981 cttaattggt aatccaaatt ctggcaagac aacgttattt aaccagctca ctggctcacg
    41041 tcagcgtgta ggtaactggg ctggcgttac cgtcgaacgt aaagaagggc aattctccac
    41101 caccgatcat caggtcacgc tggtggacct gcccggcacc tattctctga ccaccatctc
    41161 atcgcagacc tcgctcgatg agcaaatcgc ctgtcactac attttgagtg gcgacgccga
    41221 cctgctgatt aacgtggtgg atgcgtctaa ccttgagcgt aacctgtacc tgacgctaca
    41281 actgctggaa ctcggcattc cctgcattgt ggcactgaac atgctcgaca ttgccgagaa
    41341 gcaaaatatt cgtattgaaa ttgatgctct gtcggcgcgt ctgggctgtc cggtgatccc
    41401 gctggtttca acccgtggtc gcggtattga agcgctcaag ctggcgattg atcgctataa
    41461 agctaacgag aatgtggaac tggtgcatta cgcacagccg ctgctcaacg aagcagattc
    41521 actggcaaaa gtgatgcctt ccgacatccc gctgaaacaa cgtcgctggc tgggcctgca
    41581 aatgctggaa ggcgatatct acagccgcgc ctacgccggt gaagcgtcgc agcatctgga
    41641 tgccgccctc gcccgtctgc gtaatgagat ggacgatccg gcgctgcaca ttgccgatgc
    41701 gcgttaccag tgcattgctg ccatctgtga tgtggtaagc aacaccctga cggcagaacc
    41761 cagccgtttc accactgcgg tagataaaat cgtgctcaac cgtttcctcg gtctgccgat
    41821 tttcctcttt gtgatgtacc tgatgttcct gctggctatc aacatcggcg gggcgttaca
    41881 gccgctgttt gacgtcggct ccgtggcgct atttgtgcat ggtattcaat ggattggcta
    41941 cacgctccac ttcccggact ggctgactat cttcctcgcc cagggcctgg gtggcggcat
    42001 taacaccgtg ctgccactgg tgccgcagat tggcatgatg tacctgttcc tctccttcct
    42061 tgaggactcc gggtatatgg cgcgtgcggc gtttgtgatg gaccgtctga tgcaggcgct
    42121 gggcttgccg gggaaatcct ttgtgccgct gatcgtcggt ttcggttgta acgtaccgtc
    42181 ggtaatgggt gcacgtacgc ttgatgcacc gcgtgaacgt ctgatgacca tcatgatggc
    42241 accgtttatg tcctgcggcg cgcgtctggc tatcttcgca gtattcgcgg ctgccttctt
    42301 cgggcagaac ggtgcgctgg cggtcttctc gctgtatatg ctgggtattg tgatggcggt
    42361 gctgactggc ctgatgctca agtacaccat catgcgcggt gaagcgacgc cgtttgtcat
    42421 ggagttgccg gtctatcatg taccacacgt taaaagcctg attatccaga cctggcagcg
    42481 tctgaaaggc ttcgttctgc gtgctggtaa agtgatcatc atcgtcagca ttttcctgag
    42541 cgctttcaac agcttctcgc tgagcgggaa aatcgtcgat aacatcaacg actcggcgct
    42601 ggcgtccgtc agccgggtga tcaccccggt cttcaagcca attggcgtgc atgaagataa
    42661 ctggcaggca acggttggcc tgtttacagg tgccatggcg aaagaagtgg tagtgggtac
    42721 gctcaacacc ctctacaccg cagaaaatat tcaggacgaa gagttcaatc cggcagaatt
    42781 taacctcggt gaagagctgt tcagtgcgat agatgaaacc tggcagagcc tgaaagacac
    42841 cttcagcctt agcgtactga tgaaccccat tgaagccagc aaaggcgacg gcgaaatggg
    42901 taccggggcg atgggcgtga tggatcagaa attcggtagc gcagcagcag cttacagcta
    42961 cctgattttc gtcctgctgt atgtaccatg tatctcggtg atgggggcta tcgcccgtga
    43021 atcaagccgt ggctggatgg gcttctccat cctgtggggg ctgaatatcg cttactcact
    43081 ggcaacattg ttctatcagg tcgccagcta cagtcagcat ccaacttaca gcctggtgtg
    43141 cattctggcg gttatcctgt ttaacatcgt ggttatcggt ctgctgcgcc gcgcgcgtag
    43201 ccgggtggat atcgaactgc tggcaacccg caagtcggta agcagttgct gcgcagccag
    43261 caccaccggt gattgccatt aatggcttca cttattcagg tgcgcgattt gctggcgtta
    43321 cggggccgta tggaagcggc ccagataagc cagacattga acactccaca gccaatgatt
    43381 aacgccatgc tgcaacaact ggaaagtatg ggcaaagccg tgcggattca ggaagaacct
    43441 gacggctgcc tctctggcag ttgtaaaagc tgcccggaag gaaaagcctg tctgcgcgag
    43501 tggtgggcgc tgcgttaacc ttactccatc gcctgttttg gaaagcccgg tatgcgtctg
    43561 catccgggct tttttgcgtg cggctttcca taaaaatgca actcttgcag cacggcgtaa
    43621 gttcctttga aagcatctcg cagggatgaa aactcgctaa tacacaggtg tggagtggcg
    43681 cgtagagtcg cggcattcaa acaacaggtg aaggaacgcc atgagcaaaa agcagagttc
    43741 caccccacac gatgcgctgt tcaaactctt tttacgccaa ccggacacgg ctcgtgattt
    43801 tcttgcgttt catttaccgg cacccattca cgcgctttgt gatatgaaaa ccctcaagct
    43861 ggagtcgagc agctttattg atgacgatct gcgtgaaagc tattccgatg tgctgtggtc
    43921 ggtgaaaacg gaacaaggac caggatacat ctattgtctg attgaacatc aaagcacctc
    43981 aaacaaactg atcgcatttc gcatgatgcg ttacgctatt gccgcaatgc aaaatcacct
    44041 tgatgctgga tacaaaacgt tgccgatggt ggtgccattg ttgttttacc acggtattga
    44101 aagcccctat ccctattcgc tgtgttggct ggattgtttc gccgatccca aactggcaag
    44161 gcagctttat gcctccgcat ttccgctgat tgatgtcacc gtcatgcctg atgatgaaat
    44221 catgcagcac cgacgtatgg cgctgctgga gttaattcaa aaacatattc gtcaacgcga
    44281 cctgatgggg ctggtagagc aaatggcctg cttattaagt agtggatacg ctaatgacag
    44341 acaaatcaaa gggctgttta attacatact gcaaactggc gacgctgtac gttttaacga
    44401 ttttatcgac ggcgttgccg aacgttcacc gaaacacaag gagagtttaa tgactattgc
    44461 ggaaagattg cggcaggagg gggaacaatc caaagccctg catatagcca aaataatgct
    44521 tgaatccgga gttcctcttg cagacatcat gcgctttacc gggctgtcag aagaagagtt
    44581 ggctgcggcg agtcagtaaa gttctgtctc gccatttcaa aagccaccta caccctctgc
    44641 ttcaacgcca ccagcaggtg acaaaactcg gccggatgcg aaataaatgg cgcatgggcc
    44701 gctttggcga agatatatga ttcgctgtga ggccaaagtt tatccagcat cggcaccact
    44761 ttgcgcggca ccagaccgtc gagatagcca tacaatcgca aaaacggcat ggacacgttt
    44821 tgcagcggct gacggagatc gaccgttttc aggatttcca gcccgccatt aagcacgtca
    44881 acctccggca tcggtaacgc cagaacggtt ttcttcaacg cccgcgcatc ctggcgcgcc
    44941 gtttcagtcc ccatggtttg taacgccagg aaccgctcca ctgtacgctg aaaatcatca
    45001 ctgagttgct gctgaaatcc cgccagcacg tccggtttta tccccggcca ctcgtcacga
    45061 gcactaaaac aaggtgacga cgccacggtg accagcgcct gaacacgctc gggatgggtt
    45121 aacgcaatct ggcttgccac cagcccgccc agactccagc ctaaccaaat ggctttatca
    45181 ggtgcctgtt gcagcacggc ttcggccata tcagcaagtg acagcgcacc aaatccccgg
    45241 ctacgcccga agccgggcag gtcaacaagg tgcagcgtaa aatgcgagct aagttcctcg
    45301 tcaatgcaac gccacacttc ggcattcagt ccccatccgt gcagcagcac aagatgaaca
    45361 ttcccctgac ctttggtctg ccaccagatg ttattcatcc gctattgttc tcttttgact
    45421 tacaaggatg aacatatgct aacagtaccg ggattatgct ggctatgccg aatgccactg
    45481 gcgttaggtc attgggggat ttgttcggtc tgttcacgcg ccacccgcac agataaaacg
    45541 ttatgcccac aatgtggatt acccgccaca cactcccatc ttccctgcgg tcgctgcctg
    45601 caaaaaccgc cgccctggca aagactggtc acggttgccg actatgcgcc gccgttaagt
    45661 ccgcttatcc accagcttaa attttcccgg cgcagtgaaa tcgccagcgc cctgtcacgt
    45721 ctgttactat tggaagtctt acacgctcgt cgcaccaccg ggttgcaatt gccggatcgc
    45781 atcgtcagcg ttccgttatg gcagcggcgt cactggcgtc ggggatttaa tcagagcgat
    45841 ttgctgtgtc agccgttatc acgctggttg cactgccaat gggatagcga agccgtcaca
    45901 cgtacacggg ccactgcgac ccagcatttt ctcagtgccc ggctgcgcaa gcgcaacctg
    45961 aaaaatgcct ttcgtcttga attgcccgtg caaggtcgcc atatggtgat tgtggatgat
    46021 gtcgttacca ccggaagtac cgtcgcagag attgcgcagt tgcttttacg caatggtgcg
    46081 gcggctgtcc aggtctggtg cctttgtcga accttgtaga gcctcgatga tgggcgtatt
    46141 ataaccaact aaaatagtca actattaggc cattactatg atccgtattt ccgatgctgc
    46201 acaagcgcac tttgccaaac tgctggcaaa tcaggaagaa gggacacaaa tccgcgtatt
    46261 tgtgattaac cctggcacgc ctaacgctga atgtggcgtt tcttattgtc cgccggacgc
    46321 tgtggaagcc accgacacag ccctgaaatt tgacctgctg accgcgtatg ttgatgagtt
    46381 aagcgcacca tacctggaag atgcagagat cgattttgtt accgaccagt tgggttccca
    46441 gttaacgctg aaagccccga acgccaaaat gcgtaaagtg gcagacgatg caccgctgat
    46501 ggagcgcgtg gagtatatgc tgcagtcgca gatcaaccca cagcttgctg gtcacggtgg
    46561 tcgcgtttcg ctgatggaaa tcaccgaaga cggttacgcc attctgcaat ttggcggcgg
    46621 ctgtaacggt tgttccatgg tcgatgtgac gctgaaagaa gggatcgaga agcagctgct
    46681 gaacgaattc ccggagctga aaggtgtgcg cgatctcacc gaacaccagc gcggcgaaca
    46741 ctcctactac taagttatcc cctcttttgt agattgcccg atgcgacgct aaagcgtcat
    46801 ttcgggccta cgttgaacat gtgccagacg ttggcgcagc attgctttgt caaatcctcg
    46861 gttcgtttcc ccgcgataat atgaccaacc tctcataatt taaatttacc ccgctctggt
    46921 gattctcaaa cgccagatgt tacccgtatc attcacatgg gtaccaaaca tactcctgac
    46981 atctgactac aataattagt tttagtgggt atcagtcgtg gtgccgcaat atctctgttc
    47041 ccgattggga taattagagt ttgtcgtcag aaaattgacg ttacccataa caaatgaaag
    47101 gccaggtaaa tcatgccatt agtcattgtt gctatcggtg taatcttgtt gttgctcctg
    47161 atgatccgct tcaaaatgaa cggcttcatc gctctcgtcc tcgtggcgct tgctgttgga
    47221 ttaatgcaag gaatgccgct ggataaagtt attggctcca tcaaagccgg tgtcggcggg
    47281 acgctcggta gccttgccct gatcatgggt tttggcgcaa tgctgggcaa aatgctggca
    47341 gactgcggtg gcgcacaacg tatcgccacc acgctgattg ccaaatttgg taaaaaacac
    47401 atccagtggg cggtggtact gaccggtttt accgttggtt ttgccctgtt ctatgaagtg
    47461 ggctttgtgc tgatgctgcc gctggtgttt accatcgcgg cttctgcgaa tattccactg
    47521 ctgtatgttg gtgtaccaat ggcggctgca ctgtctgtga cccacggctt cctgccaccg
    47581 catccgggtc cgactgcgat tgccaccatt ttcaatgccg atatgggtaa aaccctgctg
    47641 tacggtacta ttctggcaat cccgaccgtg attctcgccg gtccggttta cgctcgcgtg
    47701 ttgaaaggta tcgataagcc aattccggaa ggtctctaca gcgcgaaaac cttcagcgaa
    47761 gaagagatgc cgagctttgg cgtcagcgtc tggacctctc tggtgccggt agtactgatg
    47821 gcgatgcgtg cgattgccga aatgatcctg ccgaaaggtc acgctttcct gccggtagcg
    47881 gagttcctcg gtgacccggt aatggcaacg ctgattgccg tgctgattgc gatgttcacc
    47941 tttggtctaa accgtggtcg ttcaatggat cagattaacg acacgctggt ttcttccatc
    48001 aaaatcattg cgatgatgct gttgatcatc ggtggtggcg gtgcgttcaa gcaggtgctg
    48061 gtagacagcg gcgtggacaa atacattgct tccatgatgc acgaaaccaa catttctccg
    48121 ctgctgatgg cctggtcgat tgctgccgta ctgcgtatcg cgctgggttc cgcaaccgtt
    48181 gcggcaatca ctgcgggtgg tatcgcggca ccgctgattg caacgacggg tgttagcccg
    48241 gagctgatgg ttattgcggt tggttccggt agtgtgattt tctctcatgt gaacgatccg
    48301 ggcttctggc tgttcaaaga gtactttaac ctgactatcg gcgagaccat caaatcctgg
    48361 tcgatgctgg aaaccattat ctcggtgtgc ggtctggtag gctgtctgct gctgaatatg
    48421 gtgatttgat aacactgact gccggatgcg gcgtgaccgc cttatccggc ctacgattcg
    48481 ggatgaatta gtaggccgga taagacgcgt caagcatcgc atccggcatc aaccgcactc
    48541 tacttcttct tcgctgcagc tctgcgccgt ctgtccaaat ccttcagcaa cttgttcacg
    48601 ccatcatcgg caaacatcga ctcaagcgtt gcggaaagct tgcgtcgcca gtttttatac
    48661 tggtaactgg tgccaggaat attcaccggt tcggccatat ccagccagtc ttccggctgt
    48721 agtcctaaca gagcactgtt actgtcggca atgtagcgct gcaaaccacg gttcagcgtc
    48781 ggcgtcatcg acatcaacga tgccttatgc ccggcacgtt tcggcagaca accatattta
    48841 tgcagtgcat ccagcagccc ttgcttcgcc agttcgcgat cctgatacag accgcgcagt
    48901 accacttcat ccggatacag ccccagggtt ttgcccagcg ttagatcccc gctctcccag
    48961 taaccgcgca gcgttggcag gtcatgtgtc gccgcaaccg ccatcgactg ctccggatac
    49021 gctttcggtg cacggaacgt cttctcgtgg tcgttttcga aatagagcac tttgtaagag
    49081 tacacaccgc tgctgcgcag cttaccgaca atctctaccg gtacggtacc gagatcttca
    49141 ccaatcacca tacagcgatg acgtttactt tcgagtgcca gaatcgagag cagatcatcc
    49201 accggatagt gaacatacgc gccctgatct gccgtctcgc catacggtat ccaccacaaa
    49261 cgcagcatcg acatcacatg gtcaattcgt aatgcgccgc agttttgcat attggcacgc
    49321 aacagctcga taaacggttc ataggcacgc gcggtgatga tatgcgggtc cattggcggt
    49381 aatccccagt tctgccccaa cgggccgagg atatccggcg gcgcgccaac cgatgctttc
    49441 aggcaatata gttcacggtc acaccaggtt tccgccccac cttccgctac gccaaccgcc
    49501 agatcacgat acaagccaat cggcatttca tagccctggc ttatctccca gcaggcggca
    49561 aactggctgt aagccagcca ctgcaaccag agataaaaat cgacgtcatc acgatgttct
    49621 tcgcagaact gacgcacttc tggtgaatcc acgttctgat acatctctgg ccatgcaggc
    49681 cagccccagc gcatttcgtc ctctttcact tgctgggcat gtagcgcatc aaaggctgcc
    49741 tgccagaaca ggctgtcgcc ctgctctgca acaaactggc gaaacgcggc catctgctca
    49801 tcatcacgtt gcgcgaaacc tttccacgcc attcgtaatg ctgtcatttt tagggcggta
    49861 accgtggagt aatcgaccca gtcggcatcg cgcgcctgtt gcagcgtctg ttgcgtggtc
    49921 ggcaactgcc accaggcctg agcctcttcg ctaagatgga aatcttcaac ggcgttaacg
    49981 tcgatataaa tcacattcag ccaacggcga gaagacgggc tgtatgggct ggcgctctcc
    50041 ggatttgccg gatagagcgc atgaatcggg ttcaggccaa tgaacgaccc gccacgtttt
    50101 gccacatcca ccagcatcgc tttgagatcg ccaaaatccc caatacccca gtttttttcc
    50161 gatcgcagcg tataaagctg aacgcaggca ccccacagct tttgtttatt cagcaacgcc
    50221 tgcggttcgt aacagcgttt cggggcgaca atcacccggc aatgcgcgcg ctggtcgtcc
    50281 tgggtgagtg tcagcgtgtg ataaccttcc ggcagcttcg tcggtagatt gaacgctttg
    50341 ccccccgtta catggccttt gtactgcgtt ccttcttcgg tggtcagcag ccagctatat
    50401 tcgccgctgc cctccaccac catcggcatt tttttgccgc tggtataaac catgacattc
    50461 gggactggcg ttaccgccac tttcgtggcg gtacgttgat gcatcgcgtc aagcaaacgc
    50521 cgtttggttt cggcgctaat cgactgcggt ttaccgtggg cattgatgta attggggcta
    50581 atccccgccg ccagcgcggc attatccaga cgtttgcttt ccatcgagct tccttagcgt
    50641 tttgcctgcc agatacgagc ctgataatcg cgaatagagc gatccgagct aaacataccg
    50701 cagcgggcgg tattgaggat cgccgcgcga gtccaggcct cctggtcgcg gtacagcaca
    50761 tccacctgct tttgtgcctc tacataggct gcgaaatccg ccatcaccag atacggatcg
    50821 ccgccctgtt tgccgatact gtgcagcatc tggtcgaagg catgcttatc gccgtcgctg
    50881 tatttaccgc tttccagctc tttcaatact gcgtccagca ccttatcttt cttccgccat
    50941 ttcaccgggt cgtagccttt ggccagaatt gccttcactt gttccacggt atgaccaaaa
    51001 ataaagatat tttcttcacc gactttctcg gcgatttcaa cgttcgcccc atccagcgta
    51061 ccgacagtaa gcgcaccatt gagcgccagt ttcatattgc cggtaccgga agcttcttta
    51121 cctgcagtcg aaatttgttc ggagatatcc gccgccggga tcagtttttc cgccgccgaa
    51181 acgcaataat ccggcaggaa caccaccttc aacttatcgc caaccagcgg atcgttgttg
    51241 atcacgtcag ccactttgtt gatcgcaaag ataatattct tcgccaggta gtagcccggt
    51301 gccgctttcg cgccgaagag gaagacgcgc ggtacgcgat cagcctgcgg gttttcacga
    51361 atttctttgt acaacgccag aatatgcagc agattcaggt gctggcgttt gtactcatgc
    51421 aaacgtttga tctgaatatc gaaaatcgcc tgtggattga tctcaatacc ggtacgaact
    51481 ttcacaaact ccgccagacg gactttattc gcctgcttga tctcgcgata ttgctgacgg
    51541 aatttcgcat catcagcgaa tttttccaga ttgatcagct gatcgagatc gttagcccac
    51601 tctttttgca gtgatttatc caacagagcc gccagtgccg ggttgcactg tttgatccag
    51661 cgacgtgggg taataccgtt ggtgacgtta tggaatttgt tcggccatag ctggtgatat
    51721 tccgggaaca gatctttcac caccagatcc gagtgcagcg ccgcaacacc gttcaccgcg
    51781 aaaccgccaa ccacacacag gttcgccata tgcacttgtt tgtcgtgcac caccgccagt
    51841 ttggcccaca ctttttcatc gcccggccag gttttctcta ccagcgtttt aaagcgagta
    51901 ttaatttcgt taataatctg catgtggcgc ggcagtaagc ctttcaccag tttcacatcc
    51961 cagcgttcca gcgcttctgg catcagggta tggttggtgt aagcgaaagt tttgctggta
    52021 atggcccagg cgtcatccca gctcatctgg tgctcatcga tcagcacgcg cagcagttct
    52081 ggaatcgcga tagttgggtg ggtatcgttc agctgaataa cttcgtaatc cgccagttcg
    52141 tgcagtttac gccccgccag atgatggcga cgcaaaatat ccgctaccga acaggcacac
    52201 tggaagtatt gctgcatcag gcgcagcttt ttaccggcag tatggttgtc gtttggatag
    52261 agaactttgg tcagtttttc cgcattgatg ccctgctgtt cggcacgcaa gaaatcaccg
    52321 tcgttaaatt tagtcagatc aaacggatgc gcgtgcgtcg cctgccacag acgcagcggc
    52381 tgcgccacgc cattacgata gccgacaacg gggagatccc acgcttgacc ggtaatggta
    52441 aactccggct cccagcgtcc gtctttcgtc actttaccgc caatccctac ctgcacatcc
    52501 agtgcttcgt tgtggcggaa ccacgggtag ttactgcgat gccagtcatc cggcgcttca
    52561 acctgtttgc catcgacaaa agactggcgg aacaaaccat attgatagtt cagaccgtaa
    52621 cccgtcgcag actgaccgac agttgccatt gagtcgagga agcacgccgc cagacgtccc
    52681 agaccaccgt tacccagcgc cgggtcgatc tcttcttcca gcaggtccgt cagattgatg
    52741 tcataagcct tcaacgaatc ctgtacatcc tgataccagc cgagattcaa caggttgttg
    52801 cccgtcaggc gaccaatcaa aaactccatt gagatgtagt taacatgtcg ctgattcgcc
    52861 accggcttgg cgaatggctg agcacgcagc atttcggcca gtgcttcact cactgctagc
    52921 caccactggc gaggagtcat ttcagccgca gaatttaagc cataacgctg ccactgacgt
    52981 gaaagcgctt cctgaaattg cttatcgtta aaaataggtt gtgacatagg agttccactt
    53041 ttcttagatt ttcaacacaa cgttatcgct agtttgccag gctcgatgtt gaccttcctc
    53101 atcctgcggg ggattaggca gggaggagtt gcggggatga gcaaggaaat gtgatctcaa
    53161 ccacttaaag ctagtgcaaa ccacaggatt agcatcaaat caatgcaata cagcgcagaa
    53221 aatctgtatc taagtgcaaa aaatggccgt tgcgtatttt caaaaagcgg aaggtaactc
    53281 tataaattaa gtaaaggagt gaaacagttt cataagtaaa atatccagtg tgctccatct
    53341 cattcttaat agatttatta agatcatctt tttagatggc actttcatca ggaatgaaga
    53401 agaaaccctt gcttaaatga atctgatgaa cataagggaa accagtattc acgctggatc
    53461 agcgtcgttt taggtgagtt gttaataaag atttggaatt gtgacacagt gcaaattcag
    53521 acacataaaa aaacgtcatc gcttgcatta gaaaggtttc tggccgacct tataaccatt
    53581 aattacgaag cgcaaaaaaa ataatatttc ctcattttcc acagtgaagt gattaactat
    53641 gctgattccg tcaaaactaa gtcgtccggt tcgactcgac cataccgtgg ttcgtgagcg
    53701 cctgctggct aaactttccg gcgcgaacaa cttccggctg gcgctgatca cgagtcctgc
    53761 gggctacgga aagaccaccc tcatttccca gtgggcggca ggcaaaaacg atatcggctg
    53821 gtactcgctg gatgaaggtg ataaccagca agagcgtttc gccagctatc tcattgccgc
    53881 cgtgcagcag gcaaccaacg gtcactgtgc gatatgtgag acgatggcgc aaaaacggca
    53941 atatgccagc ctgacgtcac tcttcgccca gcttttcatt gagctggcgg aatggcatag
    54001 cccactttat ctggtcatcg atgactatca tctgatcact aatccagtga tccacgagtc
    54061 aatgcgcttc tttattcgcc atcaaccaga aaatctcacc ctggtggtgt tgtcacgcaa
    54121 ccttccgcaa ctgggcattg ccaatctgcg tgttcgtgat caactgctgg aaattggcag
    54181 tcagcaactg gcatttaccc atcaggaagc gaagcagttt tttgattgcc gtctgtcatc
    54241 gccgattgaa gccgcagaaa gcagtcggat ttgcgatgac gtttccggtt gggcgacggc
    54301 actacagcta atcgccctct ccgcccggca gaatacccac tcagcccata agtcggcacg
    54361 ccgcctggcg ggaatcaatg ccagccatct ttcggattat ctggtcgatg aggttttgga
    54421 taacgtcgat ctcgcaacgc gccattttct gttgaaaagc gccattttgc gctcaatgaa
    54481 cgatgccctc atcacccgtg tgaccggcga agaaaacggg caaatgcgcc tcgaagagat
    54541 tgagcgtcag gggctgtttt tacagcggat ggatgatacc ggcgagtggt tctgctatca
    54601 cccgctgttt ggtaacttcc tgcgccagcg ctgccagtgg gaactggcgg cggagctgcc
    54661 ggaaatccac cgtgccgccg cagaaagctg gatggcccag ggatttccca gcgaagcgat
    54721 tcatcatgcg ctggcggcag gcgatgcgct gatgctgcgc gatattctgc ttaatcacgc
    54781 ctggagtctg ttcaaccata gcgaactgtc gctgctggaa gagtcgctta aggccctgcc
    54841 gtgggacagc ttgctggaaa atccgcagtt ggtgttattg caggcgtggc tgatgcaaag
    54901 ccaacatcgc tacggcgaag ttaacaccct gctagcccgt gctgaacatg aaatcaagga
    54961 catcagagaa gacaccatgc acgcagaatt taacgctctg cgcgcccagg tggcgattaa
    55021 cgatggtaat ccggatgaag cggaacggct ggcaaaactg gcactggaag agctgccgcc
    55081 gggctggttc tatagccgca ttgtggcaac ctcggtgctg ggtgaagtgc tgcactgcaa
    55141 aggcgaattg acccgctcac tggcgctaat gcagcaaacc gaacagatgg cacgccagca
    55201 cgatgtctgg cactacgctt tgtggagttt aatccagcaa agtgaaattc tgtttgccca
    55261 agggttcctg caaaccgcgt gggaaacgca ggaaaaagca ttccagctga tcaacgagca
    55321 gcatctggaa cagctgccaa tgcatgagtt tctggtgcgc attcgtgcgc agctgttatg
    55381 ggcctgggcg cggctggatg aagccgaagc gtcggcgcgt agcgggattg aagtcttgtc
    55441 gtcttatcag ccacagcaac agcttcagtg cctggcaatg ttgattcaat gctcgctggc
    55501 ccgtggtgat ttagataacg cccgtagcca gctgaaccgt ctggaaaacc tgctggggaa
    55561 tggcaaatat cacagcgact ggatctctaa cgccaacaaa gtccgggtga tttactggca
    55621 aatgaccggc gataaagccg ccgctgccaa ctggttgcgt catacggcta aaccagagtt
    55681 tgcgaacaac cacttcctgc aaggtcaatg gcgcaacatt gcccgtgcac aaatcttgct
    55741 gggcgagttt gaaccggcag aaattgttct cgaagaactc aatgaaaatg cccggagtct
    55801 gcggttgatg agcgatctca accgtaacct gttgctgctt aatcaactgt actggcaggc
    55861 cggacgtaaa agtgacgccc agcgcgtgtt gctggacgca ttaaaactgg cgaatcgcac
    55921 cggatttatc agccattttg tcatcgaagg cgaagcgatg gcgcaacaac tgcgtcagct
    55981 gattcagctt aatacgctgc cggaactgga acagcatcgc gcgcagcgta ttctgcgaga
    56041 aatcaatcaa catcatcggc ataaattcgc ccatttcgat gagaatttcg ttgaacgtct
    56101 gctaaatcat cctgaagtac ctgaactgat ccgcaccagc ccgctgacgc aacgtgaatg
    56161 gcaggtactg gggctgatct actctggtta cagcaatgag caaattgccg gagaactgga
    56221 agtcgcggca accaccatca aaacgcatat ccgcaatctg tatcagaaac tcggcgtggc
    56281 ccatcgccag gatgcggtac aacacgccca gcaattgctg aagatgatgg ggtacggcgt
    56341 gtaagtttag ccggataacg cgccagatcc ggcttacatc tctgcatcat tcaatgctca
    56401 cccgcgttac gccatctgtt tctatcaaac taaaccgcac cggcaagaaa cgctccacca
    56461 ccgcgatatt ggtcagcaga tggcatgagg gatgggcgac cgtaaattcc cccgcgcccg
    56521 ccagcgccat cggtagcacc agttggtcag caagatattc ccccaccgcc gccgtgcttg
    56581 ccaggtagcg tttcacctct ttcaccaact gtgccgcaac cacctcggca ctgacgcgct
    56641 tttcaccgac gacaaaaaag cgttcggtga tattttcact ttcgacttca agcgagacgg
    56701 tattacccgg cccctggtcg cgcggcaggt tatgaatatt ctgttcatgc agggaaaaac
    56761 tccccgccag tgtagcgatt tcacgctcag caacatggcg cggcacacca gctaatagaa
    56821 cttctccacg catctgcaca atgttcccgc gctcgccaag ttgcaaggtg ttaaacgatg
    56881 ccacgggcga gacttccgtt gccaccacac cgcctccggc agggtaaaaa ccgtggcgta
    56941 acagcgtggt ttgctgatga attcctattt tcgccagcag cggctccagc acccggcgga
    57001 taaaatccgc aggcggcgcc gacgggttat cggtgccgcc gctcacttca acacgcgaag
    57061 gtccatcggc aaaccacagc gcgggcagca ccgtttgcag caccagcgta caacttccgg
    57121 cgctaccgat agcaaagcgg taatcgccgc cgcgcacggt gccgggccgg aagagcagac
    57181 gctgcgaccc cagctccgcg ccttccacgg ttgctccgca aatttccgtc gccgccttta
    57241 ccgcggtcag atgctggcgc aacagccccg gtttcgcccg cccggcacga atgctggtga
    57301 tggtaaatgg ctggccggtt atcatcgaca ggctcagcgc cgagcgcagg atctgcccgc
    57361 caccttcgcc ctgtgcgcca tccagcgcaa tcatcctttt catcatttat ccttttacgc
    57421 acaccacctg acgcagggta tagataactt ccaccagatc gctttgtgcc gccatcaccg
    57481 catcaatatc tttatacgcc atcgggattt cgtcgatcac ttcggcatct ttacggcatt
    57541 ccacatgcgc ggtggcacga atttgatctt ccacgctgaa cagttttttc gctttagttc
    57601 ggctcattac ccgcccggca ccgtggctgc acgaacagaa cgactcttca tttcccagcc
    57661 cacggacgat aaagcttttt gctcccatcg aaccgggaat aattccatat tgaccagcac
    57721 gcgcagacac cgcgccttta cgcgtcacgt agatctcttc accaaagtgc tgttcttttt
    57781 gcacatagtt gtggtgacag ttgatctctt ccatcgccag cgtttgtggc tgtctgaccg
    57841 ttttctgcgt aatgctctgc aatgccgtta ccacgttttc catcatcgca tcgcggttaa
    57901 ggctggcaaa aagctgcgcc caggccacgg ctttcaggta atcatcaaag tattccgtac
    57961 cttccataaa gtacgccaga tcacgcgacg gcaacgtctc aagcgtttcc tgcatctctt
    58021 tttgtgccag atcgataaag taagtcccga tggcgttacc aattccgcgt gaaccggagt
    58081 gcagcataat ccacacctgg tccgactcat caaggcagat ttcaataaag tggttaccgg
    58141 ttcccagcgt tcccaggtgt ttatagttat tggtattcag gaaacgggga tatttttgcg
    58201 ttaaccactg ataaccggct tcaagctcag cccatttagc atcgacgtta acaggtggat
    58261 tttcccaggc acctttatca cgtttacaac ggccagtggt acgcccgtgc ggcacggccg
    58321 tttcaatcgc ctgacgcagc tctgccaggt tttcaggcag gtcttccgcc gttaacgcgg
    58381 tacgcagcgc gttcattcca cagccaatat ccacgcccac cgccgccgga ataatcgccc
    58441 ctttggtcgg gatcacgcta ccaatggtgg aacctttacc caggtgtaca tcaggcatta
    58501 ccgcaatatg tttgaaaata aacggcatct tcgccgtatt aataagttgc tgacgcgcat
    58561 cggcctctac cggcacgcct ttggtccaca tttttaccgg ggcattttca gtggtcagta
    58621 attcgtaatt cattttgttt ttctcttttc gttgtttgct gtcctgataa ttgcaaccgt
    58681 cgtgccagaa aattaaataa gcagcttaat tttttaattc attgttttaa aaaagattat
    58741 atctttacgt ccgtaaccgg agatttcccg caaagccaat ttaccgataa tgaaatatcg
    58801 tcttttataa ggatatctaa gatgcgtaaa acagtggctt ttggctttgt cggtaccgta
    58861 ctggattatg ccgggcgcgg cagtcagcgc tggtcaaaat ggcgtccgac actctgttta
    58921 tgccagcaag aatcgttggt catcgatcga ctggaattgt tgcacgacgc ccgctcgcgc
    58981 tcgctatttg aaacgcttaa acgcgatatc gccagcgttt cgccagaaac agaagtggtg
    59041 agcgttgaga ttgaactgca taacccgtgg gatttcgaag aggtctacgc ctgcctgcat
    59101 gatttcgccc gtggttacga gtttcagcca gaaaaagaag actatttaat tcacatcacc
    59161 accggtaccc acgtcgcgca gatttgctgg tttctgctgg cagaagcgcg ttacctgccc
    59221 gcccggctga tacaatcttc acctccgcgc aaaaaagaac agccgcgcgg cccaggtgaa
    59281 gtaacgatta tcgatctcga tttaagccgt tataacgcca tcgccagccg ctttgccgag
    59341 gaacgccagc aaacgcttga ttttcttaag tccggcattg ccacgcgtaa cccccacttc
    59401 aaccgcatga ttgagcagat cgaaaaagtg gcgatcaaat cccgcgcgcc gattctgctt
    59461 aacggtccaa ccggcgcggg caagtcattt ctggcgcgac gcatcttcga gttaaaacag
    59521 gcgcggcatc agtttagcgg cgcgtttgtg gaagtgaact gcgccaccct gcgcggcgat
    59581 accgccatgt cgacgctgtt tggtcatgta aaaggcgcgt ttaccggggc gcgggaatct
    59641 cgtgaaggtt tattacgcag cgccaacggc ggaatgttgt ttcttgatga gattggcgaa
    59701 ctgggcgcag acgaacaggc aatgctgctg aaagccattg aagagaaaac cttttacccg
    59761 tttggcagcg atcgccaggt gagcagtgat tttcagctta tcgccggaac ggtgcgcgat
    59821 ttgcgccagc tggttgccga aggcaaattt cgcgaagatc tgtacgcgcg gatcaatctc
    59881 tggaccttca ccctgccggg tctacgccag cgccaggaag atattgaacc gaacctggat
    59941 tatgaagtgg agcgccacgc ctcactcact ggcgacagcg tgcgttttaa caccgaagcg
    60001 cggcgcgcct ggttggcttt tgcgacctct ccccaggcaa catggcgcgg taactttcgc
    60061 gaactttctg ccagcgtcac gcggatggcc acctttgcca ctagcggacg catcactctg
    60121 gacgtggttg aagatgagat aaaccgtctg cgctataact ggcaggagag ccgcccctcc
    60181 gcgcttacgg cgttgctggg cgcagaggca gaaaacatcg atctcttcga ccgtatgcaa
    60241 ctggaacacg ttatcgctat ctgccgccag gcaaagtcgc tttccgcagc cggacgccag
    60301 ctttttgacg tttcgcgcca gggcaaagcc agcgtcaatg acgcggatcg gctacgcaaa
    60361 tacctggcgc gttttggtct gacgtgggaa gccgtgcagg atcagcacag ctccagttga
    60421 atatggtggt ccgtcagcac ctgcatcacg cttactggcg gcggggcgtc ggtgtagacg
    60481 gcatctacca tgctgatgct gcccatattg accatcgcgt tacggccaaa tttcgagtga
    60541 tcgacaacca gcataacgtg gcgcgagttc tcaataatgg cgcgtttggt gcgaacttcg
    60601 tggtaatcga actccagcag cgagccgtcg ctatcgatgc cgcttatccc cagaatgccg
    60661 aaatcaaggc ggaactggga gataaaatcg agcgtcgctt cgccaatgat cccgccatcg
    60721 cggctgcgta attcgccacc ggcgagaatg atgcgaaaat cttcttttac catcaacgtg
    60781 ttagcaacgt tgagattgtt ggtgacaatg cgcaaattgc tgtgattgag cagtgcgtgc
    60841 gctaccgctt ccggcgtggt gccgatatcg ataaacagcg tcgagccatt ggagatttgc
    60901 tccgccactt tgcgggcgat gcgctctttt tcttcggtct gggtggcctt gcgatcgtgc
    60961 cacggcgtgt taaccgaact ggaaggcagc gccgcaccgc catgatggcg caggatcagg
    61021 ttttgctccg ccagctcatt gaggtcgcgg cgaatagtct gcgggctgac ggagaaatgc
    61081 tctaccagct cttcggtact gacataaccc tgctgtttaa ccagttcgat aataccgttg
    61141 tgacgttgtg tttgtttcat ttataaatcc ctggaattat tttcgttttc gcgcattgag
    61201 cgaatcaaca aaagccatcg ctaaacccac ggctaacccg gcgatgtgtg ctccgttcgc
    61261 catcgacatc ccaaacaaat caaaccatcc ggcgacaatc cagatcagcg caaagataat
    61321 taacccacgt tgcaggtaaa tgccactttg cggatcgcgt tcgccacgta gccagacgta
    61381 gcccatcagc gcatacacca cgccagaaag cccgccaaac cacggcccgc tgaatttttg
    61441 ctgcacatag ccgcttaaca gggcgctgat aagcgtaatg acaattagct taccgctacc
    61501 gaggcgtttt tccaccgcac cgccgagata ccaccaccag agcaggttaa agaggatatg
    61561 catcagcgag aagtgcatta acgcgtgggt gaagtaacgc cagaactcaa atttcagtgt
    61621 tggatcgaat ggccaggcca gccataacat cacttcctga tcgccgagaa tttgcatggc
    61681 aataaacacc accacgcaga cgatcatcat cacccaggtt accggacctg cgcgttcacg
    61741 caaggcggca aagaaaggat aacggcgata atgcaggcca ctgccggtat ggcctgcctg
    61801 ccagctcgcc gccagataac gcggatctgc cgggttttcg agaaaacgcg ccagctccgc
    61861 ccgtacgcgc tcggcctggg actcatccgc cagccagaca tcgctttggt tatgttgttg
    61921 aatcgtgagg ataacaccct gcgtcgccat gtaatcaaca aacgcctgcg ccacgcgggg
    61981 gttagcaaaa gaggtaatca tcaacatcgt tgctgtcgct tattccacac aaaaggggac
    62041 agtataaagc gttacgcgcc gtacgccacc tctgcgggaa actgacgttg ccaggcttca
    62101 aagccgccgt caatgctata gaccacatcg tagccctgtt gcagcagata ctgcgccgcg
    62161 cctttgctgc tattgccgtg ataacacatc accatcaccg gagtgtcaaa gtcgttatca
    62221 cgcataaaag cgcccagcgt gtcgttggtt aaatggaaag cctgcaccgc atgtcccatt
    62281 gcgaaactct gtggatcgcg aatatcgacc agcaccgcct ctttttcctg caacttctgg
    62341 tgcgcgtcgg caacgttaat acattcgaac tgatccatgc gtctctcttt ctttacaaac
    62401 aagtgggcaa atttaccgca cagtttacgt cgaagcggca gataaacgcc ataatgttat
    62461 acatatcact ctaaaatgtt ttttcaatgt tacctaaagc gcgattcctt gctaatatgt
    62521 tcgataacga acatttatga gctttaacga aagtgaatga gggcagcatg gaaaccaaag
    62581 atctgattgt gatagggggc ggcatcaatg gtgctggtat cgcggcagac gccgctggac
    62641 gcggtttatc cgtgctgatg ctggaggcgc aggatctcgc ttgcgcgacc tcttccgcca
    62701 gttcaaaact cattcacggt ggcctgcgct accttgagca ctatgaattc cgcctggtca
    62761 gcgaggcgct ggctgaacgt gaagtgctgc tgaaaatggc cccgcatatc gccttcccga
    62821 tgcgttttcg cctgccacat cgtccgcatc tgcgcccggc gtggatgatt cgcattggtc
    62881 tgtttatgta cgatcatctg ggtaaacgca ccagcttgcc gggatcaact ggtttgcgtt
    62941 ttggcgcaaa ttcagtgtta aaaccggaaa ttaagcgcgg attcgaatat tctgactgtt
    63001 gggtagacga cgcccgtctg gtactcgcca acgcccagat ggtggtgcgt aaaggcggcg
    63061 aagtgcttac tcggactcgc gccacctctg ctcgccgcga aaacggcctg tggattgtgg
    63121 aagcggaaga tatcgatacc ggcaaaaaat atagctggca agcgcgcggc ttggttaacg
    63181 ccaccggccc gtgggtgaaa cagttcttcg acgacgggat gcatctgcct tcgccttatg
    63241 gcattcgcct gatcaaaggc agccatattg tggtgccgcg cgtgcatacc cagaagcaag
    63301 cctacattct gcaaaacgaa gataaacgta ttgtgttcgt gatcccgtgg atggacgagt
    63361 tttccatcat cggcactacc gatgtcgagt acaaaggcga tccgaaagcg gtgaagattg
    63421 aagagagtga aatcaattac ctgctgaatg tgtataacac gcactttaaa aagcagttaa
    63481 gccgtgacga tatcgtctgg acctactccg gtgtgcgtcc gctgtgtgat gatgagtccg
    63541 actcgccgca ggctattacc cgtgattaca cccttgatat tcatgatgaa aatggcaaag
    63601 caccgctgct gtcggtattc ggcggtaagc tgaccaccta ccgaaaactg gcggaacatg
    63661 cgctggaaaa actaacgccg tattatcagg gtattggccc ggcatggacg aaagagagtg
    63721 tgctaccggg tggcgccatt gaaggcgacc gcgacgatta tgccgctcgc ctgcgccgcc
    63781 gctatccgtt cctgactgaa tcgctggcgc gtcattacgc tcgcacttac ggcagcaaca
    63841 gcgagctgct gctcggcaat gcgggaacgg taagcgatct cggggaagat ttcggtcatg
    63901 agttctacga agcggagctg aaatacctgg tggatcacga atgggtccgc cgcgccgacg
    63961 acgccctgtg gcgtcgcaca aaacaaggca tgtggctaaa tgcggatcaa caatctcgtg
    64021 tgagtcagtg gctggtggag tatacgcagc agaggttatc gctggcgtcg taaattaacg
    64081 taaggtgatc aggtcagatt tcaatctggc ctgagactga tgacaaacac aaaactgcct
    64141 gatgcgctac gcttatcagg cctacgtggt ttatgcaata tattgaattt gcatggtctt
    64201 gtaggccaga taagacgttc acgtcgcatc cggcatgaac aaagcgcact ttgtcaaaaa
    64261 tctaacctac tttttaattc agggaattac cgcaaagccc acgccatcat acccaacgta
    64321 acaaaactca ggcacgttcc ccactcgccc cgagaaaaat agcattaatg cgcccagcgc
    64381 cagcataaaa attttgagca gaaggtaaat tgttggcgtg ataaggatat tacaaacttc
    64441 aataataccg gcaagtccga cacccagcat ggcaataacc accgccaaaa attgcgccag
    64501 tatggggatg ccgaaaaaag tcattaccag cgaggtcaaa atccattttc tgttttgcat
    64561 tattctttcc attctttttg aatggtgaaa ttatactccc cgagtcccct tgccccttct
    64621 ggacactttt ccgaaatgat ggcggaaaaa aacgggaccc tttggccccg ttctatttat
    64681 tggtgaactt acaatctcac cggatcgata tgccagatat gatcggcgta ctctttgata
    64741 gtacggtcag aagagaagta gcccatattg gcaatgttca gcatcgcttt tgcggtccac
    64801 tcttcctgaa gctcgtagag ttcatcgact ttatcctgac aatcgacata gctgcgataa
    64861 tccgccagta cctggtagtg atcgccgaag ttgatcagcg aatcaaccag atcgcgatag
    64921 cgacccggat cttccggact gaatacaccg ctgccgattt gcgtcagcac ctgatgcagc
    64981 tcctcatctt tctcgtagta ttcacgcggt ttgtagccct gacgacgcag ttcttccact
    65041 tcttccgctg tgttaccaaa aataaagata ttgtcagcac cgacatgatc cagcatctcg
    65101 acattcgcac cgtccaacgt accgatagtc agcgcaccgt taagcgcaaa cttcatgtta
    65161 ctggtgccgg aagcttccgt ccctgccagc gaaatctgtt cagacagatc tgccgccgga
    65221 atgatcaact gcgccaggct aacgctgtag ttcgggatga acacgacttt cagcttatcg
    65281 ccaatctgcg gatcgttgtt gatcactttc gctacgtcat tgatcaaatg aataatgtgc
    65341 ttcgccatgt aataggccga agccgcctta ccgccaaaaa tattcacgcg cggtacccac
    65401 ttcgcatccg ggtcggcctt gatgcggtta tagcgggtaa tcacatgcaa cacattcatc
    65461 aattgacgtt tgtattcgtg aatacgtttg atttgtacat cgaacaacgc ctttggattc
    65521 accaccacat tcagctgctg ggcgatatac tctgccagac gctttttgtt ctccagcttc
    65581 gcctgatgca cagcgtgatt aaccattggg aaatcacagt gttgttgcag ctcattaagc
    65641 aggctaaggt cggtgcgcca gttacggccc aggtgttcgt ccagcacggc tgaaagcgat
    65701 gggttcgcta ccgccagcca gcgacgcggc gtcacaccgt tggtgacgtt ggtgaaacga
    65761 cccgggaaga ttttcgcaaa gtcggcaaac aacgattgca ccatcagatt agagtgcagt
    65821 tccgatacac cgttaacttt gtggctcaca acaaccgcca gccaggccat acgcacacga
    65881 cgaccgttgg attcatcaat gatcgacgcc cgtcccagca gatcggtatc gttcggatac
    65941 tgttcctgca aggttttcag gaaatagtcg ttgatttcaa agatgatctg caggtgacgc
    66001 ggcagaattt tacccagcat atcaaccggc caggtttcca gcgcctcgct catcagcgtg
    66061 tggttagtgt aggagaagac ctgacaacac acctcaaacg cgtcgtccca gctaaattgg
    66121 tgctcatcga tcagcagacg catcatctca ggaatcgaca gtaccggatg ggtatcattg
    66181 agatgaatcg cgattttatc cgccaggtta tcgtaggttt tatgcaactg ataatggcgg
    66241 cttaaaatgt cctgaatggt cgaggaaacc aggaagtatt cctgacgcag gcgcagctca
    66301 cgcccggagt aggtggagtc atccggatac agtacgcgag atacgttctc ggagtggttt
    66361 ttatcttcca ctgccgcgaa gtagtcaccc tggttgaatt taccgaggtt aatttcgcta
    66421 ctggcttgcg cactccacaa acgcagcgtg ttggtcgcgt cggtgtcgta accagggatt
    66481 atctgatcgt aagcgactcc cagaatctct tcggtttcaa tccagcgcgt ttttttacct
    66541 tcctgctgaa tgcgaccgcc aaaacggact ttatagcgcg tgttgtggcg tttgaattcc
    66601 cacgggttac cgtattccag ccagtagtct ggcgactctt tctggctacc gttaacgatg
    66661 ttctgcttga acataccgta gtcatagcgg atgccgtaac cgcgccccgg caaccctaac
    66721 gtcgccagag aatcaaggaa gcaagccgcc agacgtccca ggccaccgtt accgaggcct
    66781 gggtcatttt cttcatcaat cagctcttcg agatttaacc ccatcgcttc cagtgcgccc
    66841 tgtacatctt cgtaaattcc tagcgacaac atggcgttgg agagcgtacg gccaatcaaa
    66901 aactccatcg acaggtagta aacctgacga gtttcttgcg acaactgggc acggtttgaa
    66961 cgtaaccagc gctccacgag acgatcgcgc acagcaaata acgttgcgtt cagccattca
    67021 tgtttattgg cgacgaccgg gtcctttcca atcgtaaaca tcagcttgta agcgatagag
    67081 tgcttaagag cttctacgct aagcgtgggc gatgaatatg taaacggagc attcatatag
    67141 gcgtttcctg aaaactattt caagcgatag taaagctcac ggtacgactt cgccgcgacc
    67201 tgccagctaa aatccattgc catagcctga cgttgcacaa accgccacag tgaaggacgg
    67261 gaccacagta caaaagcacg tcgaatagcc cgtaacagcg accaggcatt actatcttca
    67321 aagacaaacc cactggcgac gccatctgca aggttctcaa gagaacagtc agaaaccgta
    67381 tcagcaagcc caccggtgcg ccgcactaac ggcagcgtac cgtacttcaa tccataaagt
    67441 tgcgttaagc cgcacggttc aaaacggctg ggcaccagaa tgacgtccgc gccgcccata
    67501 atgcgatgcg aaaatgcttc gtgatagcca atctgaacgc ccacctgacc ggggtattcc
    67561 gctgccgccg caaggaaacc ttcctgcagc accggatcgc ccgcgccgag tagcgccagc
    67621 tgcccgccct gctccagaag acccggtaag gcttccagca ccaggtcgag acctttctgg
    67681 ctggtcagac ggctcaccac tgcaaaaagc ggcactttat cgtcaacctt aagccccatt
    67741 gcgatttgta actggcgctt attttccgct ttatcttcca acgtatcgcg ggtgtaacgc
    67801 gaggccaaca gtaagtccgt ctctggactc cagattttct cgtccacgcc gttcagtacg
    67861 ccggaaagac gcccttcacg gtgacgctgt tgcaacagac cttccatacc gtaggcaaac
    67921 tgcggttcgg tgatctcgcg agcgtaggtt ggactgaccg ccgtaatgtg atcggcatag
    67981 tacagaccgg ccttcaggaa agagatttgt ccgttgaatt ccagcccatg aatattaaag
    68041 aatgaccatg gcaattggat gtcattcatg tgatgtgcat aaaacatgcc ttgataggcc
    68101 aggttgtgca cagtaaacac cgacttcgcc ggacgcccgc gcgccgccag atacgcaggc
    68161 gcaaggcctg catgccagtc gtgcgcatgc accacatcag gacgccagaa tgggtcaagc
    68221 ccgctggcca tttctgcccc aacccacccc agcagcgcaa aacgcaatac gttgtcggta
    68281 taggcaaata agttggtatc gtgatacggg cttcccggac gatcatagag atgcggcgcg
    68341 tcaatcaggt aaatgccaac cccgttgtaa tgaccgaaca acagcgtgat atgtccggcg
    68401 aaggtatcac gacgggatac tacctgcgca tcggtcacgc cacggcgaat atcgggaaat
    68461 gcaggcaaca gtacgcgagc gtcaacgccg tctgcgattt gtgctgcggg taatgcccca
    68521 ataacatcag ccagaccgcc ggttttaagc agcgggaaca tctctgaaca tacatgtaaa
    68581 acctgcatta tcgctcctgt ttatgcccta acttccgtag catttcgcgc gttaccagca
    68641 cgatgccttc ttctgaacga tagaaacgac gtgcatcttc ctctgcgttt tcaccaatca
    68701 ccatgccttc cggaataaca caagcacgat cgatgacgca gcggcgcaga cggcacgagc
    68761 gacctaccca tacttccggt aacaatacgg cggaatcaat gttgcagaat gaattcacgc
    68821 gaacgcgcga gaacagaacg gactgcacca ccaccgaacc ggagatcaca caaccgccgg
    68881 aaaccagtga gttaagggtc atcccgtggc taccggagcg atcctgcacg aatttcgctg
    68941 gcggtaatga ttcattgtag gtgcgaattg gccaattgcg atcgtacata tccagttccg
    69001 gcaccacaga ggccagatcg aggttcgctt tccagtaagc ttccagcgta cccacatcgc
    69061 gccagtacgg ctcggcatcc gggtcggatt gtacgcaaga gagcgggaac gggtgcgcat
    69121 aggccagacc ggcttcggtg atcttgggaa tcaaatcttt gccaaagtcg tggctggagt
    69181 tctcatcgcg atcgtcttct tccagcagtt catacagata gtcggcgtca aagacgtaga
    69241 tacccatact cgccagagat ttgctcggat cgttcggcat tgacggcggg ttagcaggtt
    69301 tttcaacgaa ttcgataatt ttatcgttct catcaaccgc cataacgcca aatgcggagg
    69361 cttcttcaat cggtactggc atacaagcaa cggtgcaacg tgcgcctttt tcgacgtgat
    69421 cgataagcat acgcgagtag tcttgcttgt agatatggtc gcccgccagg atcaccacgt
    69481 attccgcttt ataacggcgg ataatgtcga ggttttgggt gaccgcatct gcggtgccgc
    69541 gataccagtt ttcccctttc attctctgct gtgctggcag cagatcgaca aactcgttca
    69601 tttcttcatt gaagaatgac cagccgcgct gaatgtgctg caccagagtg tgggactggt
    69661 actgggtgat cacgcccata cgacggatcc cggagttgat gcagttagac agcgcaaagt
    69721 cgataatgcg gaacttaccg ccgaagtgta cggccggttt tgctcgctta ttggttaaat
    69781 ccttcaggcg ggtaccacgt cctcccgcca gtatcagggc aacagatttc aatggcagct
    69841 ggcgcgccaa cattaagtga tcgttcttct ctaaactaac catgactaac tcctttttta
    69901 tcatctctgg aacacacaca atccgtgtgc aggtccctgc cagacagccg taatcactgg
    69961 gttatcctct ccagcgaatg ggggaatggc gtgccactcc ccagcaggta aaacaatctc
    70021 tgttacctca agcgtggcgt taattgcgat caaaaagcga tccgagagca gaatttgcag
    70081 ctgtttcggc ccgttttgcc actcatccgt gcttaaaggt tgagcatatc gatttagcca
    70141 acggacattg ccgtcgcctt cttcccacca gcgattctcc accaaagcgg gaatgcgctt
    70201 gcgcagatgg attaacgcgg cggtaaatgc ggttaaacca ctgcttgcct gcgaccagtc
    70261 caaccaggtt aattggttat cctgacagta ggcattgtta ttgccatgct ggctgtgacc
    70321 atgttcgtca ccggccagta acatcggcgt accctgggag agcaacaacg ttgttaacag
    70381 ggcgtgaatg ctgtcgcgcc gccgttcaac caggtcaaga gaaccgccta acccttcttt
    70441 accatgattg ttactgtaat tgttgttggt cccgtcgcga ttttcttctc cgtttgcttc
    70501 attgtgttta tggttgaagc aaacgcagtc gcgaagcgta aaaccgtcat gcgcggtgac
    70561 gagattaatc gcggcactcg gcagacgacc attacgttta aaaacatcgc tggaggcagc
    70621 aaaacgcccg gcaaacgccc ccagaggcaa atcataatgt agccagaaac gacgggcagc
    70681 atcgcggaaa tgatcgttcc actcggcaaa cagcggcggg aaatttccca cctgataacc
    70741 accaggagcg atatcccacg gttcagcaat taacttcacc tgcgagagca ccgggcagtt
    70801 ctggatagcg gtaaacaacg gcgcatcctg acggaactct ggcgtacggc ccatgactgc
    70861 cgccagatca aagcggaaac catcgacgtg gcaggtttct acccaataac gcaggcaggc
    70921 gctggcataa tccaccaccg ccggatgact caaattgagc gtgttgccgc aaccggtcca
    70981 gttgtgataa tcgccgtctt ctcttatcca ataatagcta cggttatcga tcccacgcag
    71041 cgagaataac gggccgtcga ggtccagttc cgcactatgg ttgagcacga tatcaagaat
    71101 gacttcgata cccgctttat gcagtgcttt gattgcatcg cgaaactcat ccagcgccgt
    71161 ttctggcgag caggcatacg ccggatgcag cgcaaacatc gccaccgggt tgtaacccca
    71221 gtagttactt agccccatgc gttgcagacg tggttcactg gcaaactgcg ccactggcag
    71281 cagttccagc gcggtaatgc ccaattgttt caaatagttg atcatcaccg gatgcccgag
    71341 ggctttataa gtgccacgga tctcgaccgg gatctccggg tgcaagtacg ttaatccttt
    71401 gacatgggct tcataaatga tggtgctgcc ccacggcgtg cgcggcgggg catcatcttc
    71461 ccagtcatag tgatcaacca ccactacgca tttcggcgca atggcggcgt tgtcgcgata
    71521 gtcaggttca ttatgaccgg cgtgcagcag cgggttatct ttaaactccc cgtcaatttg
    71581 ccgcgcgcaa ggatcaatca acaacttcgc cgggttaaag cgatgcccct cggcgggttg
    71641 ccaggggcca tgaacgcgat aaccataacg caaacccggg cgcgcatccg gcagataacc
    71701 gtgccaaatg tcgccactgt gccctggcaa gtcatagcga tgttcctggc cattggcgtc
    71761 aaagacacac agttctaccc gctcggcatg agcggagaaa agtgtgaagt tgacgccctg
    71821 accgtcgtaa tgcgcgccga ggggagcggg tttgccaatg gcgagttgtg tcattctgcc
    71881 tcccgaacca gccagatagt ggccagcggt ggtagcgtca ggcttagtga atgctgacga
    71941 ccgtggctgg caatctcatc gctgtgtacc gtgccgccat tgcctgcatt actgccgtga
    72001 tagtgcatgg aatcggtatt gaggatttca cgccatttgc ccggctggtt tatgccgaag
    72061 cgataatcat gacgcggtac cggcgtaaag ttactggcaa cgatgatttc gttaccctct
    72121 ttatcgcgac gcacaaagat cagcaccgag cgttctttgt catccaccac cagccattca
    72181 aagccgtacg ggtcaaaatc cagttcatgc attgctttat ggtggcggta ggtgaggttc
    72241 agatcgcgca ccagacgctg gacaccgtgg tgccagttat cgccgccttc caacagatgc
    72301 cagtcgaggc tggcgtcatg gttccactcg cggccctggg caaattcgtt acccatgaac
    72361 agtagtttct tgcccgggaa tgcccacatc cagccatagt aggcgcgcag gttcgcgaat
    72421 ttctgccatg cgtcgcccgg catgcggtcg agaatcgatt ttttaccgtg gaccacttca
    72481 tcatgcgaca acggcaggac gaagttttca gtgtagttgt agagaatccc gaaggtcagt
    72541 ttatcgtgat gatactgacg ataaaccggg tcgagcttca tgtagtccag ggtgtcatgc
    72601 atccagccga ggttccactt gtaccagaag cccagaccgc ccatatcctg cggacgagaa
    72661 acgccaggga aatcggtaga ctcctcagcc attgtcaccg caccggaaac ctgctcacca
    72721 agaatacggt tggtattacg caagaattca atcgcttcaa gattctcgcg cccgccaaat
    72781 tcgttcggga tccactcccc ctctttacgg ctgtagtcgc gataaatcat tgacgccacc
    72841 gcatcgacgc gcagcgcatc aataccaaaa cgttcaatcc agtaaagcgc gttaccgacg
    72901 aggaagttac tgacttcacg gcgaccatag ttgtagatca gcgtgttcca gtcctgatga
    72961 tagccttcac gcggatcgct gtgttcatac aagttcgtgc catcaaattc ggcaagcgca
    73021 aagtcatcag tcgggaagtg gcctggcacc cagtcgagaa tcacgttcag accagctgcg
    73081 tgtgcggcat caatgaaata acggaagtcg tcgcgagtac caaaacggcg ggttggcgca
    73141 tacaggccgg ttggctgata accccaactg ccatcgaagg gatgctcgtt aatgggcagt
    73201 agttcgaggt gggtaaagcc catccattta gcataaggca ccagttgatc ggccagctcg
    73261 cggtagctca accagaaatt gttgtcggtg tggcgacgcc aggaacccag gtgaacttca
    73321 taaatagaga ttggcgcatc aaactgattc gcttttttgc gctcttcagt ctgtacaacc
    73381 ttttccggca gcccgcaaat aagagacgcg gtttccgggc gcatttgcgc ttcaaaggca
    73441 taagggtcgg acttcagacg caagttgcca ttggcatcaa tcatctcgta tttatagagc
    73501 tgaccgttat gcgccccagg gataaacagt tcccagatgc cgctctcttt acgcaggcgc
    73561 atcgggtgac ggcgaccgtc ccagtagttg aattgcccaa ccaccgagac ccgacgggcg
    73621 tttggagccc agacagagaa acgcgtacct gtgacgccat ccatagtatc tgcatgcgcg
    73681 cctaaggttt catacgggcg caggtgagta ccttcagata atagccaggc atccatttcc
    73741 tggattagcg gaccaaaacg gtaaggatca tcaatcaggt tttgctgacc atgccagaca
    73801 acagccaact gatagcggaa aaaattctta cgtcgcggaa tgacgccgct aaagaatccc
    73861 cgtgagtcga gacactccag ttttgcgagt ttgcgcccgg ttttcggttc aatcacccac
    73921 acatcggtag cgtcgggtaa aagggcacgg acttccagtc ccgcggtggt tttatgcatt
    73981 cccagtacgg aaaaaggatc cgcaaaatgg cctgcaatta gcgcgttaat cacgtctcta
    74041 tcgatacgat cggacatgct tgtcttcctg ttttattgtg tcaccccatc caattggatt
    74101 tttgacttct ggttgtgaca tttttttgac ctgaacggcg cagcactctg tgcatcctct
    74161 ctgcgtcgtc ctcacttcag gtaaggctgt gaatactcat gtattcagcc acccttaaag
    74221 aatagccaat gctctattta actcccggta aatcatgaaa catctgcgct tactcctgta
    74281 ttacgcacta acaggggcgg catcgcgccc cagatttaat gaataaagat tacgccagtt
    74341 gacgaagcat ccgacgcagc ggctccgcgg ccccccacag cagctggtcg cccacggtaa
    74401 aggctgacag gaactctggt cccatattca gcttacgcag gcggcctacc ggcgtggtca
    74461 gcgtgccggt aacggcagct ggggttagct cacgcatagt gatttcccga tcgttcggaa
    74521 cgactttcgc ccacggattg tgcgcagcca gcagttcttc cacggtcgga atagacacat
    74581 cttttttcaa tttaatagtg aatgcctggc tgtggcagcg caatgccccg acacgcacac
    74641 ataaaccatc taccggaatt acggaagatg tgttgaggat cttgttggtt tccgcctgcc
    74701 ctttccactc ttcgcggctc tgaccgttat cgagctgttt gtcgatccac ggaatcaggc
    74761 tacccgccag cggcacgcca aagttatcca ccggcagctc accgctacgg gttaaggttg
    74821 tgactttgcg ttcgatatcg agaatagcag aggacggggt cgcgagttca tctgccacat
    74881 ggccatacag atggcccatc tgggttaata actcacgcat atgtcgcgca ccaccgccgg
    74941 aagcggcctg gtaggttgca acggacaccc aatcaacaag atcattggcg aataaaccac
    75001 ccaacgacat caacatcagg cttacggtac agttaccgcc aacaaaagtc ctgatgccat
    75061 tatttaatcc gtcggtaatg acgtcctgat tgacggggtc aagaatgatg atggcgtcat
    75121 ctttcatgcg cagagacgat gctgcgtcaa tccagtaacc ttgccatccg ctttcacgaa
    75181 gctttggata gatttcgttg gtataatcgc cgccctgaca ggtcacaatg atatcgaggg
    75241 cctttagcgc ctccagatca aaggcatcct gaagtgtgcc agtggttccg ccaaaagacg
    75301 gcgcagcctg gccaagctga gaagtagaaa agaagacagg gcgaatggcg tcgaagtcgc
    75361 gctcttcaac catgcgttgc atgagaacgg agccgaccat accgcgccag ccgataaaac
    75421 caacattttt cataagcgtt tttttcctgc aaagatgtgt gctgtataaa tgtgccggtc
    75481 tcctcttggc acatctttca ccatacaaaa agcagccaaa gtcgcaagtg aaattaatca
    75541 atgatagcga agccatcagt aatgcgactt atcctgcttt gttagcacgc agaaagtccg
    75601 cggcaattat cagggaattt gagttatgaa tgaaatcatt tctgcagcag ttttattgat
    75661 cctgattatg gatccgctcg gaaacctacc tattttcatg tccgtactga aacatactga
    75721 accgaaaaga cggcgggcaa tcatggtgcg agagttgctt attgctctcc tggtgatgct
    75781 ggtgttcctg tttgcgggtg agaaaattct ggcatttctt agcctacgag cagaaaccgt
    75841 ctccatttct ggcggcatca ttctgtttct gatcgccatt aaaatgattt tccccagcgc
    75901 ttcaggaaat agcagcgggc ttccggcagg tgaagagcca tttatcgtgc cgttggcaat
    75961 tccgttagtc gccgggccga ctattctcgc cacgctgatg ttgttgtctc atcagtaccc
    76021 gaatcagatg gggcatctgg tgattgctct gctgctggcc tggggcggca cctttgtcat
    76081 cctgctacag tcttcgctat ttttacgtct gctgggcgag aaaggggtga acgcacttga
    76141 acgcctgatg ggattgattc tggtgatgat ggcaacccag atgttcctcg acggcattcg
    76201 aatgtggatg aaggggtaac gaggagagtt tttcgaaaag aacccggtag cgtcacaact
    76261 accgggcgaa caaacttaac tcaacagctg gaacgcaatc atcccaacga tggcaccgac
    76321 agtgccgagg atggtttcca tcatggtcca ggttttcagc gtttcggctt cggtcgcgcc
    76381 ggtaaattta ccgaacaacc agaaaccggc gtcgttaacg tggctgacaa caatcgaacc
    76441 accagcgata caaatcgaca gcgccgccat ttgcgcaccg gagtagttca gttgttcaat
    76501 aaccggcatc accagtccta ccgccgttaa acaggctacg gtggcagaac cctgaatgat
    76561 gcgcactgca gctgccagca cgaagcaggt gatagcaatc ggcaggccca tgccggttaa
    76621 cgcttcgccc agtgccggac ctacgccaga gtcaaccagc acctgtttga acacgccgcc
    76681 cgcaccaatc accagcagaa tgatccccgc cggttgcagc gcgtgaccgc aaatctccat
    76741 cactttgtct tttggcatgc cctgacgcat tgccagaccg taaatcgcca ccagacaagc
    76801 aaccagaatc gcggtaaacg gatgaccgat aaactcaaac cattcgtaag cagttgatcc
    76861 ttccggcaca aaacgcgcgg caatggtttt cagccctacc agcaccagcg gcagcaggat
    76921 cagcgacagg ctgaatccga aagatggcat tttgccttcg ccgagatgcg gttcgctgat
    76981 gtcgtcagga atatgcagct caacgtaacg gctgatgaag ttaccccaca gcggcccggc
    77041 aataatcatt cccggaattg ccgcacacag gccaatcagg atcatccagc caaagtcggc
    77101 attcatctgc gatgccagca gcatcggcgc tggtccaggc accagaaatg ccgccgctgc
    77161 cgccacgcct gcaaataatg ggattaccag cttcaccagg ttcgtaccgg tgtggcgcgc
    77221 cattgagaaa gcaacgctaa tcagcagaac tatcgccact tcaaagaaca gcggtagcgc
    77281 acagaccagc cccgcaaggc cgatggcata atgcgcgcgg ctgtgaccga aggatttgag
    77341 cattttgacg gcaatctgat cgactgcgcc ggtttcatgt aagatcttgc caaacatagc
    77401 tcccagggcg acaaccaccg ccaggaagcc gagggtgcct cccatccctt tttccatcgt
    77461 cgctgcgatt ttatcgagcg gcataccaga aaaaaggcca gcccccatgg acaccaccat
    77521 taaagccagg aaagcgtgca tacgcgcctt catgactaaa aacagcagca gtaaaacaga
    77581 ccctactgct gttaaaacaa gcgttaatgt agtcactact tatttgcctt ttttaataac
    77641 ctcaatggtg cttgccacaa caccttccag cggttgatcg atatccacca ccagtacatc
    77701 ggtttcgtcc gcacccggct cctgcagcgt ttcaaactgc gtcaccaaca tttgggtttt
    77761 aaagaaatgg cctttgcgcg ctttcaggcg gctttcaatc acatcaaaat cgcctttcaa
    77821 atagatgaaa gagagattcg gattaccttc acgcagcaag tcgcgatagt gttttttcaa
    77881 tgcagaacag acgatcagcg acactttatt agtgcgctgc atagcaaacg cggcgtcgtt
    77941 cagcgcctgc aaccacggtt tgcgatcgtc gtcattcagt ggttcgccag acgccatttt
    78001 ttcgatattg cgccgtggat ggaggaaatc gccatcaaga aacgcggcat gaagttgatg
    78061 cgccacttca ctggcgaccg cagatttgcc gctgcccgat acgcccatca agacgtaaat
    78121 gtggtgatca tggttagtcg tgctcaaagt ggtgccccca caatacaaga attaaaaatg
    78181 ttacgggtaa ctgttatcgg taacattgtc cagccggaca atatcagaag caatatccat
    78241 ccatgcctta agtgtataag tgtgagctac ttcaaatttg tgggcttaaa tagatccgcc
    78301 cggtgacaag gtgaaaccta aatctaacat tttcggtgtc acagattcgc cacgaatacg
    78361 cgccagcagg cgttcagcgc caatactgcc catccgctca cgcggcgtca gcacgctcgc
    78421 aagtcgtggc tccatcacct gaccaatgtc atgaccgtgg aaaccggcaa tcgccatatc
    78481 gtcaggaact tttaacccca gacgctgaca ttcaaacgcc gcgccgaccg ccaggtcatc
    78541 attcgtacag aacacgccat ccagctgcgg atattcccgc cgcgcctggc gaatcagttc
    78601 aataccggaa gagtaagaag aagattgctc aaccatcacg ctatatggca ccaggcctgc
    78661 atccagcatc gcctgttcgt atcccttctg tttgatgata gtacgttcgt cgagacgtgc
    78721 gccgagatag gcaatgtggc gatgcccgcg agcaataatg gcagtggtca tctggcgtgc
    78781 tgcttcaaag ttatcaaaac cgacggcgat atcaaggcat ggcgacttgc tgtccatcag
    78841 ttccaccacg ggaatacccg ccacttcaat catctttaag gtgcgcggcg tgtgggtacg
    78901 ttcggtgagg atcaggccgt cgatattcca ggagagcatg gattcgaggc gttcttgctc
    78961 catttccggt ttataaccgt agtgcgccag catggtctga taaccgtgcg cgtcggtgac
    79021 gctttcgatt ccgcgtaata cttccgcgaa aacctggttg gtgagagaag gtaacaggac
    79081 gccaatcgcc cggctggtgg cgttagagag gatatcgggc gcacgattgg gaatatagcc
    79141 cagttcatca agagccgcgg caatcttgcc gcgtagagcg acggaaacct gctccgggtt
    79201 gcgtaaaaaa cggctgaccg tcattttggt cacgcctaca cggtcagcca catcctgaag
    79261 tacgggtctt ttctttttca tcgtcctgaa ggtacaaaag agatagattc tcttagttta
    79321 acacggacac atcagaacct tcccggggaa aacagtgctt gtttacaatt attagatata
    79381 cactaaatca attgcatcgc attgtgctaa cgacgcggca aaaccccgga agcgtacatc
    79441 agcacgcgac cggagcgagc gaggaagcct gcaaaaaggc aggcttcaaa gatgccgttg
    79501 agttttaaac cggcggcaga tcgaacagta acacttcgct gtcgctatcc gcatggatgg
    79561 agattgcctg ctcatcccag attgccagac catcgctggt cgaggctttc acgccgttaa
    79621 tggtgacatt gcctttcacc acctggatcc agacgcggcg ttcagcggca atctgatgca
    79681 ccgactgctc atctttcagc aacgcccagc ggtacagttc catatcctga tgcactttca
    79741 atgaaccatc tcgcgcatcc ggcgagagca ccagctgttt gccctgtacg gcatcgaagc
    79801 gacgctgttc ataacgcggc gtaataccgt tttcttcagg catgatccag atctgataca
    79861 gatgcagacg ctcggtgctg cttgggttgt actctgagtg acgaataccc gtaccagcac
    79921 tcataatctg gaactcaccc gccggaacct gctctttatt gcccatgctg tcctgatgct
    79981 caacagtacc ttccagcacg taggtcaaaa tttccatatc tttatgcggg tgagtgccga
    80041 agccctgccc tgcttcaatc acgtcgtcgt taatcacgcg cagcgcggag aagcccataa
    80101 agttcggatc gtaatagttg gcaaaagaga aagtatgcca ggagtccagc cagccatgat
    80161 ttgcatgacc acgttcattt gctttgcgta agtagatcat ttgtattcgc cccctgaatg
    80221 atttcgatgg gcttagtgtg gacccgatct gcctgggatg atagagggtg aaaattgacc
    80281 cctctgttca aaaaaattga actattcgag gggccatcaa acttacttag cgagagttac
    80341 tgtggaggga gaggcttgct caaatccgcg ttcaaggatt tccagattgg taagaacttc
    80401 agattccttg acgtaatttg gcgcaccgtg ggtgatggtt tgatacaacg catcataaac
    80461 gcgcccgtaa tcgcccatct ccggcttcat ctcttctctg accgtcacgc cctcgtcatt
    80521 gacatactcc agcacaccga ccgaatcatc cgctgcgaat cccggttcgc ccggcataat
    80581 attagccttc aggctggttt cctgctggtc gataccgtat ttaataaacg aacctttctt
    80641 accgtgaacg ataaatttcg gataatcgat tttcaccaga tggctggttt tgacgatggc
    80701 tttcaggtcg ccataaaaca gttgcgcttc aaaggtgtcg tcaggattgg ctttattacg
    80761 caggctgcgg atgtcataag cgacgtgatc cgggcgaccg aacagagaaa taatctggtc
    80821 catcgtatgc acaccaaggc cataaaacgc gccatcctgc ggcagcccag gtttggtttc
    80881 tgccaccggg cggtaatagt caaaatggct ttccacttca acaatctctc ccaacttgcc
    80941 actttcaatc gcttttttcg ctgtcaggaa gcaggagtca aagcgacgat tctgatacgg
    81001 cgtgacggtc agccctttgc ttttcgccaa cgcaaacagc tctttcgcct gcgcaagtgt
    81061 cggagtgaac ggtttttcga ccagcacatt tttcccggct tccagcgcgc gtttcgcgta
    81121 ctcgaaatgg ctgtccgcgt gggtgcagac aacaaccagc ttaacatcgg gatcgtttag
    81181 tacttcgtcg agatcgctgg tgaaatggat atgggaataa atgggagcct gttcttccgg
    81241 cttcgcatgg cgacgaaaaa tatgcgcgac atgccagcta tccttgcggt taagtacata
    81301 cggcagatgg taacgggtgg tgcttttgcc gaagccaata aaggcgcagt tgatgaccat
    81361 gatttcgtcc tttttaaggt ggttatttac accttagcgc aaagcggacg tggttcctac
    81421 tggagtgcgc ataacgaaca caagcactcc cgtggataaa ttgagaacga aagatcaaaa
    81481 aaaaagccag cacccggctg gctaagtaat actggaagca atgtgagcaa tgtcgtgctt
    81541 tcaggttctc cgcgagggtc ttcctgatcg cgagacaata ataatcattc tcattcgcac
    81601 ttgtccaaca ctttttgcaa aaaaatgcat ttgactcgca tttgaaagtc aatgatgttg
    81661 aaagggacat ttaccccaaa gaggacaaag gaatgagtga gatagtaata cgccacgcag
    81721 aaacacggga ttacgaggcc atcaggcaga ttcacgccca gccggaggtg tattgcaaca
    81781 cactacaggt gcctcatcct tccgatcata tgtggcagga gcgactcgcc gatcgtcccg
    81841 gcatcaagca actcgtcgcc tgtattgatg gagacgtcgt gggccatctc accattgacg
    81901 tgcaacagcg cccacgccgc agtcatgttg ccgattttgg tatctgtgtc gactctcgtt
    81961 ggaagaaccg cggcgtcgcc agcgccctga tgcgagagat gattgaaatg tgcgacaact
    82021 ggttgcgggt agatcgcatt gaactaaccg tgtttgtcga taacgccccg gcaattaagg
    82081 tctataaaaa atacggcttt gaaattgaag ggactggtaa gaagtacgca ttgcgtaatg
    82141 gtgaatatgt cgatgcatat tatatggcgc gggtgaagta agatagtgcc ctttttctga
    82201 gatggaaaaa gggtgtcatt caaaatcgac ataccttcct ttaaggtatt tatttgccca
    82261 atacatatat tgagatttaa ctcataatta cttcctaaag tgtaatattt tattttttaa
    82321 tatatacgcc tacaatttcc tggagtaaat aaataacaat taacaagcat aatattgcca
    82381 ttgataaaat agcatgccat aaaaggactt ttcagggatg agtaatattg tttacctgac
    82441 agtaacggga gaacaacaag gaagcatctc cgcaggttgt gggacttctg agtctacagg
    82501 taatcgttgg cagagcgggc atgaggatga aatatttaca ttctcactct taaataatat
    82561 taataatacg gggcttggtt cacagttcca tggtataaca ttttgtaaat taattgataa
    82621 aagcactcca tt
//
LOCUS       DAPOAV010000007        78184 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.007, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000007 DAPOAV010000000
VERSION     DAPOAV010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 78184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78184
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.007"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            539..2107
                     /gene="cydA"
                     /locus_tag="RN951_000596"
     CDS             539..2107
                     /gene="cydA"
                     /locus_tag="RN951_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415261.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HDX2525655.1"
                     /translation="MLDIVELSRLQFALTAMYHFLFVPLTLGMAFLLAIMETVYVLSG
                     KQIYKDMTKFWGKLFGINFALGVATGLTMEFQFGTNWSYYSHYVGDIFGAPLAIEGLM
                     AFFLESTFVGLFFFGWDRLGKVQHMCVTWLVALGSNLSALWILVANGWMQNPIASDFN
                     FETMRMEMVSFSELVLNPVAQVKFVHTVASGYVTGAMFILGISAWYMLKGRDFAFAKR
                     SFAIAASFGMAAVLSVIVLGDESGYEMGDVQKTKLAAIEAEWETQPAPAAFTLFGIPD
                     QEEETNKFAIQIPYALGIIATRSVDTPVIGLKELMVQHEERIRNGMKAYSLLEQLRSG
                     STDQAVRDQFNSMKKDLGYGLLLKRYTPNVADATEAQIQQATKDSIPRVAPLYFAFRI
                     MVACGFLLLAIIALSFWSVIRNRIGEKKWLLRAALYGIPLPWIAVEAGWFVAEYGRQP
                     WAIGEVLPTAVANSSLTAGDLIFSMVLICGLYTLFLVAELFLMFKFARLGPSSLKTGR
                     YHFEQSSTTTQPAR"
     gene            2123..3262
                     /gene="cydB"
                     /locus_tag="RN951_000597"
     CDS             2123..3262
                     /gene="cydB"
                     /locus_tag="RN951_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HDX2525656.1"
                     /translation="MIDYEVLRFIWWLLVGVLLIGFAVTDGFDMGVGMLTRFLGRNDT
                     ERRIMINSIAPHWDGNQVWLITAGGALFAAWPMVYAAAFSGFYVAMILVLASLFFRPV
                     GFDYRSKIEETRWRNMWDWGIFIGSFVPPLVIGVAFGNLLQGVPFNVDEYLRLYYTGN
                     FFQLLNPFGLLAGVVSVGMIITQGATYLQMRTVGELHLRTRATAQVAALVTLVCFALA
                     GVWVMYGIDGYVVKSTMDHYAASNPLNKEVVREAGAWLVNFNNTPILWAIPALGVVLP
                     LLTILTARMDKAAWAFVFSSLTLACIILTAGIAMFPFVMPSSTMMNASLTMWDATSSQ
                     LTLNVMTWVAVVLVPIILLYTAWCYWKMFGRITKEDIERNTHSLY"
     gene            3277..3390
                     /gene="cydX"
                     /locus_tag="RN951_000598"
     CDS             3277..3390
                     /gene="cydX"
                     /locus_tag="RN951_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-I oxidase subunit CydX"
                     /protein_id="HDX2525657.1"
                     /translation="MWYFAWILGTLLACSFGVITALALEHVESGKAGQEDI"
     gene            3390..3683
                     /gene="ybgE"
                     /locus_tag="RN951_000599"
     CDS             3390..3683
                     /gene="ybgE"
                     /locus_tag="RN951_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyd operon protein YbgE"
                     /protein_id="HDX2525658.1"
                     /translation="MSKIIATLYAVMDKRPLRALSFVMALLLAGCMFWDPSRFAAKTS
                     ELEIWHGLLLMWAVCAGVIHGVGFRPQKVLWQGIFCPLLADIVLIVGLIFFFF"
     gene            3833..4237
                     /gene="ybgC"
                     /locus_tag="RN951_000600"
     CDS             3833..4237
                     /gene="ybgC"
                     /locus_tag="RN951_000600"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
                     /protein_id="HDX2525659.1"
                     /translation="MNTTLFRWPVRVYYEDTDAGGVVYHASYVAFYERARTEMLRHHH
                     FSQQALMAERVAFVVRKMTVEYYAPARLDDMLEIQTEITSMRGTSLVFTQRIVNAENT
                     LLNEAEVLVVCVDPLKMKPRALPKSIVAEFKQ"
     gene            4234..4926
                     /gene="tolQ"
                     /locus_tag="RN951_000601"
     CDS             4234..4926
                     /gene="tolQ"
                     /locus_tag="RN951_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system protein TolQ"
                     /protein_id="HDX2525660.1"
                     /translation="MTDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNA
                     AAREAEAFEDKFWSGIELSRLYQESQGKRDNLTGSEQIFYSGFKEFVRLHRANSHAPE
                     AVVEGASRAMRISMNRELENLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVK
                     QATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILH
                     RQAFTVSESNKG"
     gene            4930..5358
                     /gene="tolR"
                     /locus_tag="RN951_000602"
     CDS             4930..5358
                     /gene="tolR"
                     /locus_tag="RN951_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin uptake protein TolR"
                     /protein_id="HDX2525661.1"
                     /translation="MARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVE
                     VDLPDATESQAVSSNDNPPVIVEVSGIGQYTVVVEKDRLERLPPEQVVAEVSSRFKAN
                     PKTVFLIGGAKDVPYDEIIKALNLLHSAGVKSVGLMTQPI"
     gene            5423..6688
                     /gene="tolA"
                     /locus_tag="RN951_000603"
     CDS             5423..6688
                     /gene="tolA"
                     /locus_tag="RN951_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="HDX2525662.1"
                     /translation="MSKATEQNDKLKRAIIISAVLHVILFAALIWSSFDENIEASAGG
                     GGGSSIDAVMVDSGAVVEQYKRMQSQESSAKRSDEQRKMKEQQAAEELREKQAAEQER
                     LKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAA
                     KKAAADAKKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEK
                     AKAEAEKKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAA
                     AAKAAAEKAAAAKAAAEADDIFGELSSGKNAPKTGGGAKGNNASPAGSGNTKNNGASG
                     ADINNYAGQIKSAIESKFYDASSYAGKTCTLRIKLAPDGMLLDIKPEGGDPALCQAAL
                     AAAKLAKIPKPPSQAVYEVFKNAPLDFKP"
     gene            6821..8113
                     /gene="tolB"
                     /locus_tag="RN951_000604"
     CDS             6821..8113
                     /gene="tolB"
                     /locus_tag="RN951_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001646851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system protein TolB"
                     /protein_id="HDX2525663.1"
                     /translation="MKQALRVAFGFLILWASVLHAEVRIVIDSGVDSGRPIGVVPFQW
                     AGPGAAPEDIGGIVAADLRNSGKFNPLDRARLPQQPGSAQEVQPAAWSALGIDAVVVG
                     QVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTASDEVFEKLTGIK
                     GAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVT
                     FESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLA
                     SGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNINGGAPQRITWEGSQN
                     QDADVSSDGKFMVMVSSNGGQQHIAKQDLATGGVQVLSSTFLDETPSLAPNGTMVIYS
                     SSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAWSPYL"
     gene            8148..8669
                     /gene="pal"
                     /locus_tag="RN951_000605"
     CDS             8148..8669
                     /gene="pal"
                     /locus_tag="RN951_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-associated lipoprotein Pal"
                     /protein_id="HDX2525664.1"
                     /translation="MQLNKVLKGLMIALPVMAIAACSSNKNASNDGSEGMLGAGTGMD
                     ANGGNGNMSSEEQARLQMQQLQQNNIVYFDLDKYDIRSDFAQMLDAHANFLRSNPSYK
                     VTVEGHADERGTPEYNISLGERRANAVKMYLQGKGVSADQISIVSYGKEKPAVLGHDE
                     AAYSKNRRAVLVY"
     gene            8679..9470
                     /gene="cpoB"
                     /locus_tag="RN951_000606"
     CDS             8679..9470
                     /gene="cpoB"
                     /locus_tag="RN951_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein CpoB"
                     /protein_id="HDX2525665.1"
                     /translation="MSSNFRHQLLSLSLLVGIAAPWAAFAQAPISSVGSGSVEDRVTQ
                     LERISNAHSQLLTQLQQQLSDNQSDIDSLRGQIQENQYQLNQVVERQKQILLQIDSLS
                     SGGAAAQSTSGDQSGAAASTTPTADAGTANAGAPVKSGNANTDYNAAIALVQDKSRQD
                     DAMVAFQNFIKNYPDSTYLPNANYWLGQLNYNKGKKDDAAYYFASVVKNYPKSPKAAD
                     AMFKVGVIMQDKGDTAKAKAVYQQVISKYPGTDGAKQAQKRLNAM"
     gene            9635..9710
                     /locus_tag="RN951_000607"
     tRNA            9635..9710
                     /locus_tag="RN951_000607"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9668..9670,aa:Lys,seq:ttt)
     gene            9846..9921
                     /locus_tag="RN951_000608"
     tRNA            9846..9921
                     /locus_tag="RN951_000608"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9879..9881,aa:Val,seq:tac)
     gene            9924..9999
                     /locus_tag="RN951_000609"
     tRNA            9924..9999
                     /locus_tag="RN951_000609"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9957..9959,aa:Lys,seq:ttt)
     gene            10149..10224
                     /locus_tag="RN951_000610"
     tRNA            10149..10224
                     /locus_tag="RN951_000610"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10182..10184,aa:Val,seq:tac)
     gene            10228..10303
                     /locus_tag="RN951_000611"
     tRNA            10228..10303
                     /locus_tag="RN951_000611"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10261..10263,aa:Lys,seq:ttt)
     gene            10450..10525
                     /locus_tag="RN951_000612"
     tRNA            10450..10525
                     /locus_tag="RN951_000612"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10483..10485,aa:Lys,seq:ttt)
     gene            10658..10733
                     /locus_tag="RN951_000613"
     tRNA            10658..10733
                     /locus_tag="RN951_000613"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10691..10693,aa:Lys,seq:ttt)
     gene            10764..10889
                     /locus_tag="RN951_000614"
     ncRNA           10764..10889
                     /ncRNA_class="other"
                     /locus_tag="RN951_000614"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
     gene            11166..12209
                     /gene="nadA"
                     /locus_tag="RN951_000615"
     CDS             11166..12209
                     /gene="nadA"
                     /locus_tag="RN951_000615"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HDX2525666.1"
                     /translation="MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVM
                     VAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEK
                     TILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
                     ELIDHLDSLGEKIIWAPDKHLGRYVQKQTGGDILCWQGACIVHDEFKTQALTRLQEEY
                     PDAAILVHPESPQAIVDMADAVGSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPD
                     KELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALEQEGSNHEVHVDERLRERALVP
                     LNRMLDFAATLRG"
     gene            12247..12966
                     /gene="pnuC"
                     /locus_tag="RN951_000616"
     CDS             12247..12966
                     /gene="pnuC"
                     /locus_tag="RN951_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HDX2525667.1"
                     /translation="MDFFSVQNILVHIPIGAGGYDLSWIEAVGTIAGLLCIGLASLEK
                     ISNYFFGLINVTLFGIIFFQIQLYASLLLQVFFFAANIYGWYAWSRQTSQNEAELKIR
                     WLPLPKALSWLAVCVVSIGLMTVFINPVFAFLTRVAVMIMQALGLQVVMPELQPDAFP
                     FWDSCMMVLSIVAMILMTRKYVENWLLWVIINVISVVIFALQGVYAMSLEYIILTFIA
                     LNGSRMWINSARERGSRALSH"
     gene            complement(12963..13904)
                     /gene="zitB"
                     /locus_tag="RN951_000617"
     CDS             complement(12963..13904)
                     /gene="zitB"
                     /locus_tag="RN951_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family zinc transporter ZitB"
                     /protein_id="HDX2525668.1"
                     /translation="MAHSHSHTSSHLPEDNNARRLLYAFGVTAGFMLVEVVGGFLSGS
                     LALLADAGHMLTDTAALLFALLAVQFSRRPPTIRHTFGWLRLTTLAAFVNAIALVVIT
                     ILIVWEAIERFRTPRPVEGGMMMAIAVAGLLANILSFWLLHHGSEEKNLNVRAAALHV
                     LGDLLGSVGAIIAALIIIWTGWTPADPILSILVSLLVLRSAWRLLKDSVNELLEGAPV
                     SLDIAELKRRMCREIPEVRNVHHVHVWMVGEKPVMTLHVQVIPPHDHDALLDQIQHYL
                     MDHYQIEHATIQMEYQPCHGPDCHLNEGVSGHSHHHH"
     gene            complement(14018..14398)
                     /locus_tag="RN951_000618"
     CDS             complement(14018..14398)
                     /locus_tag="RN951_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgS-like family protein"
                     /protein_id="HDX2525669.1"
                     /translation="MKMTKLATLFLTATLSLASGAALAADSGAQTNNGQANAAADAGQ
                     VAPDARENVAPNNVDNNGVNTGSGGTMLHSDGSSMNNDGMTKDEEHKNTMCKDGRCPD
                     INKKVQTGDGINNDVDTKTDGTTQ"
     gene            14714..15766
                     /gene="aroG"
                     /locus_tag="RN951_000619"
     CDS             14714..15766
                     /gene="aroG"
                     /locus_tag="RN951_000619"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroG"
                     /protein_id="HDX2525670.1"
                     /translation="MNYQNDDLRIKEIKELLPPVALLEKFPATENAANTVAHARKAIH
                     KILKGNDDRLLVVIGPCSIHDPVAAKEYATRLLALREELKDELEIVMRVYFEKPRTTV
                     GWKGLINDPHMDNSFQINDGLRIARKLLLDINDSGLPAAGEFLDMITPQYLADLMSWG
                     AIGARTTESQVHRELASGLSCPVGFKNGTDGTIKVAIDAINAAGAPHCFLSVTKWGHS
                     AIVNTSGNGDCHIILRGGKEPNYSAKHVAEVKEGLNKAGLPAQVMIDFSHANSSKQFK
                     KQMDVCADVCQQIAGGEKAIIGVMVESHLVEGNQSLESGEPLAYGKSITDACIGWEDT
                     DALLRQLANAVKARRG"
     gene            complement(15924..16676)
                     /gene="gpmA"
                     /locus_tag="RN951_000620"
     CDS             complement(15924..16676)
                     /gene="gpmA"
                     /locus_tag="RN951_000620"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000301556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HDX2525671.1"
                     /translation="MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKL
                     LKEEGYSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAE
                     TAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDR
                     VIPYWNETILPRMKSGERVIIAAHGNSLRALVKYLDNMSEEEILELNIPTGVPLVYEF
                     DENFKPLKRYYLGNADEIAAKAAAVANQGKAK"
     gene            complement(16878..17918)
                     /gene="galM"
                     /locus_tag="RN951_000621"
     CDS             complement(16878..17918)
                     /gene="galM"
                     /locus_tag="RN951_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-epimerase"
                     /protein_id="HDX2525672.1"
                     /translation="MLNETPALAPDGQPYRLLTLRNNAGMVVTLMDWGATLLSARIPL
                     SDGSVREALLGCASPECYQDQAAFLGASIGRYANRIANSRYTFDGETVTLSPSQGVNQ
                     LHGGPEGFDKRRWQIVNQNDRQVLFALSSDDGDQGFPGNLGATVQYRLTDDNRISITY
                     RATVDKPCPVNMTNHVYFNLDGEQSDVRNHKLQILADEYLPVDEGGIPHDGLKSVAGT
                     SFDFRSAKIIASEFLADDDQRKVKGYDHAFLLQAKGDGKKVAAHVWSADEKLQLKVYT
                     TAPALQFYSGNFLGGTPSRGTEPYADWQGLALESEFLPDSPNHPEWPQPDCFLRPGEE
                     YSSLTEYQFIAE"
     gene            complement(17912..19060)
                     /gene="galK"
                     /locus_tag="RN951_000622"
     CDS             complement(17912..19060)
                     /gene="galK"
                     /locus_tag="RN951_000622"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001713229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HDX2525673.1"
                     /translation="MSLKEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVL
                     PCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSLDAPIVAHENYQWANYVRGVVKH
                     LQLRNNSFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQE
                     AENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPKGVAVVIINSNFKRTL
                     VGSEYNTRREQCETGARFFQQPALRDVTIEEFNAVAHELDPIVAKRVRHILTENARTV
                     EAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKAVIGDKGGVRMTGG
                     GFGGCIVALIPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC"
     gene            complement(19064..20110)
                     /gene="galT"
                     /locus_tag="RN951_000623"
     CDS             complement(19064..20110)
                     /gene="galT"
                     /locus_tag="RN951_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HDX2525674.1"
                     /translation="MTQFNPVDHPHRRYNPLTGQWILVSPHRAKRPWQGAQETPAKQV
                     LPAHDPDCFLCAGNVRVTGDKNPDYTGTYVFTNDFAALMSDTPDAPESHDPLMRCQSA
                     RGTSRVICFSPDHSKTLPELSVAALTEIVKTWQEQTAELGKTYPWVQVFENKGAAMGC
                     SNPHPHGQIWANSFLPNEAEREDRLQKEYFAEQKSPMLVDYVQRELADGSRTVVETEH
                     WLAVVPYWAAWPFETLLLPKAHVLRITDLTDAQRSDLALALKKLTSRYDNLFQCSFPY
                     SMGWHGAPFNGEENQHWQLHAHFYPPLLRSATVRKFMVGYEMLAETQRDLTAEQAAER
                     LRAVSDIHFRESGV"
     gene            complement(20120..21136)
                     /gene="galE"
                     /locus_tag="RN951_000624"
     CDS             complement(20120..21136)
                     /gene="galE"
                     /locus_tag="RN951_000624"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415280.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HDX2525675.1"
                     /translation="MRVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVI
                     ERLGGKHPTFVEGDIRNEALMTEILHDHAIDTVIHFAGLKAVGESVQKPLEYYDNNVN
                     GTLRLISAMRAANVKNFIFSSSATVYGDQPKIPYVESFPTGTPQSPYGKSKLMVEQIL
                     TDLQKAQPDWSIALLRYFNPVGAHPSGDMGEDPQGIPNNLMPYIAQVAVGRRDSLAIF
                     GNDYPTEDGTGVRDYIHVMDLADGHVVAMEKLANKPGVHIYNLGAGVGNSVLDVVNAF
                     SKACGKPVNYHFAPRREGDLPAYWADASKADRELNWRVTRTLDEMAQDTWHWQSRHPQ
                     GYPD"
     gene            complement(21397..22869)
                     /gene="modF"
                     /locus_tag="RN951_000625"
     CDS             complement(21397..22869)
                     /gene="modF"
                     /locus_tag="RN951_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter ATP-binding protein
                     ModF"
                     /protein_id="HDX2525676.1"
                     /translation="MSSLQILQGTFRLSDTKTLQLPQLTLNAGDSWAFVGSNGSGKSA
                     LARALAGELPLLKGERQSQFSHITRLSFEQLQKLVSDEWQRNNTDMLGPGEDDTGRTT
                     AEIIQDEVKDAPRCMQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILD
                     EPFDGLDVASRQQLAERLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGA
                     KEELLQQALVAQLAHSEQLEGVQLPEPDEPSARHALPANEPRIVLNNGVVSYNDRPIL
                     NNLSWQVNPGEHWQIVGPNGAGKSTLLSLVTGDHPQGYSNDLTLFGRRRGSGETIWDI
                     KKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDK
                     RTADAPFHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISE
                     GETQLLFVSHHAEDAPACITHRLEFVPDGGLYRYVLTKIY"
     gene            complement(22937..23725)
                     /gene="modE"
                     /locus_tag="RN951_000626"
     CDS             complement(22937..23725)
                     /gene="modE"
                     /locus_tag="RN951_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum-dependent transcriptional regulator"
                     /protein_id="HDX2525677.1"
                     /translation="MQAEILLTLKLQQKLFADPRRISLLKHIALSGSISQGAKDAGIS
                     YKSAWDAINEMNQLSEHILVERATGGKGGGGAVLTRYGQRLIQLYDLLAQIQQKAFDV
                     LSDDDALPLNSLLAAISRFSLQTSARNQWFGTITARDHDDVQQHVDVLLADGKTRLKV
                     AITAQSGARLGLDEGKEVLILLKAPWVGITQDEAVAQNADNQLPGIISHIERGAEQCE
                     VLMALPDGQTLCATVPVNEATSLQQGQNVTAYFNADSVIIATLC"
     gene            23854..24003
                     /gene="acrZ"
                     /locus_tag="RN951_000627"
     CDS             23854..24003
                     /gene="acrZ"
                     /locus_tag="RN951_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux pump accessory protein AcrZ"
                     /protein_id="HDX2525678.1"
                     /translation="MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQ
                     PGQNH"
     gene            24170..24943
                     /gene="modA"
                     /locus_tag="RN951_000628"
     CDS             24170..24943
                     /gene="modA"
                     /locus_tag="RN951_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDX2525679.1"
                     /translation="MARKWLNLFAGAALSFAVAGNALADEGKITVFAAASLTNAMQDI
                     ATQFKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTATRQ
                     TLLGNSLVVVAPKASVQKDFTIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKL
                     GAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGVKVVATFPEDSHKKV
                     EYPVAVVEGHNNATVKAFYDYLKGPQAAEIFKRYGFTIK"
     gene            24943..25632
                     /gene="modB"
                     /locus_tag="RN951_000629"
     CDS             24943..25632
                     /gene="modB"
                     /locus_tag="RN951_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HDX2525680.1"
                     /translation="MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGK
                     ALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVM
                     SFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARS
                     LGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEW
                     LARISRERAGR"
     gene            25635..26693
                     /gene="modC"
                     /locus_tag="RN951_000630"
     CDS             25635..26693
                     /gene="modC"
                     /locus_tag="RN951_000630"
                     /EC_number="7.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein
                     ModC"
                     /protein_id="HDX2525681.1"
                     /translation="MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAI
                     SGLTRPQKGRIVLNGRVLNDAEKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMS
                     KSMVDQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLD
                     IPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWG
                     SSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQ
                     ASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKTLWARISPWARDELA
                     IKPGLWLYAQIKSVSITA"
     gene            complement(26694..27512)
                     /gene="ybhA"
                     /locus_tag="RN951_000631"
     CDS             complement(26694..27512)
                     /gene="ybhA"
                     /locus_tag="RN951_000631"
                     /EC_number="3.1.3.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyridoxal
                     phosphate/fructose-1,6-bisphosphate phosphatase"
                     /protein_id="HDX2525682.1"
                     /translation="MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTG
                     RHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVIKALQLIEMLNEHHI
                     HGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFAL
                     THDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENV
                     VAFGDSFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI"
     gene            27667..28662
                     /gene="pgl"
                     /locus_tag="RN951_000632"
     CDS             27667..28662
                     /gene="pgl"
                     /locus_tag="RN951_000632"
                     /EC_number="3.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconolactonase"
                     /protein_id="HDX2525683.1"
                     /translation="MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVS
                     PDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYN
                     AGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDG
                     HLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTL
                     DMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQ
                     PRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH"
     gene            complement(28703..29656)
                     /locus_tag="RN951_000633"
     CDS             complement(28703..29656)
                     /locus_tag="RN951_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308823.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX2525684.1"
                     /translation="MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEED
                     LHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPT
                     AVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFT
                     PLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLD
                     WFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKD
                     AVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG"
     gene            29860..30891
                     /locus_tag="RN951_000634"
     CDS             29860..30891
                     /locus_tag="RN951_000634"
                     /EC_number="5.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalomesaconate tautomerase"
                     /protein_id="HDX2525685.1"
                     /translation="MMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGNDLEIDGIG
                     GGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGAFAIENGL
                     IAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVALTFLNAA
                     GTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELDADKALLA
                     RIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRALAITGAI
                     AISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRASVIRTTRK
                     IFSGEVYLP"
     gene            30967..32400
                     /locus_tag="RN951_000635"
     CDS             30967..32400
                     /locus_tag="RN951_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HDX2525686.1"
                     /translation="MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIV
                     GLVIKPFPEPVVLLIAVAASMVVVGNLSDGAFKTTAVLSGYSSGTTWLVFSAFTLSAA
                     FVTTGLGKRIAYLLIGKIGNTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSV
                     AVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISW
                     GGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLG
                     VFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGII
                     GLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAML
                     PVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGA
                     VLTILTFLVHITLGVWWWNMLIGWNML"
     gene            32583..34844
                     /locus_tag="RN951_000636"
     CDS             32583..34844
                     /locus_tag="RN951_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415292.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydratase"
                     /protein_id="HDX2525687.1"
                     /translation="MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSS
                     HNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGT
                     INGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTM
                     AVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVK
                     NKVMEFVGPGVSALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQL
                     NPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAH
                     GKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPS
                     SQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREG
                     SKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQG
                     FVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRS
                     NPIGLAEFTLSRRDPGYVSRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPL
                     QTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQM
                     AEVPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIK
                     AGSLINFNKNRQM"
     gene            complement(35078..36361)
                     /locus_tag="RN951_000637"
     CDS             complement(35078..36361)
                     /locus_tag="RN951_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl-CoA thioester hydrolase"
                     /protein_id="HDX2525688.1"
                     /translation="MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPI
                     LSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVD
                     AAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPA
                     DWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENT
                     LGDSVDAGNHPAVALRTDGDQVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVT
                     NSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFN
                     AFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVD
                     DNDEIQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK"
     gene            complement(36513..36989)
                     /locus_tag="RN951_000638"
     CDS             complement(36513..36989)
                     /locus_tag="RN951_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase inhibitor"
                     /protein_id="HDX2525689.1"
                     /translation="MKLISNDLRDGDKLPHRHVFNGMGYDGDNISPHLAWDDVPAGTK
                     SFVVTCYDPDAPTGSGWWHWVVVNLPADTRVLPQGFGSGLVAMPDGVLQTRTDFGKTG
                     YDGAAPPKGETHRYIFTVHALDIERIDVDEGASGAMVGFNVHFHSLASASITAMFS"
     gene            complement(37048..38337)
                     /gene="bioA"
                     /locus_tag="RN951_000639"
     CDS             complement(37048..38337)
                     /gene="bioA"
                     /locus_tag="RN951_000639"
                     /EC_number="2.6.1.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /protein_id="HDX2525690.1"
                     /translation="MTTDDLAFDQRHIWHPYTSMTSPLPVYPVVSAEGCELILSDGRR
                     LVDGMSSWWAAIHGYNHPQLNAAMKSQIDAMSHVMFGGITHAPAIELCRKLVAMTPQP
                     LECVFLADSGSVAVEVAMKMALQYWQAKGEARQRFLTFRNGYHGDTFGAMSVCDPDNS
                     MHSLWKGYLPENLFAPAPQSRMDGEWDERDMVGFARLMAAHRHEIAAVIIEPIVQGAG
                     GMRMYHPEWLKRIRKICDREGILLIADEIATGFGRTGKLFACEHAEIAPDILCLGKAL
                     TGGTMTLSATLTTREVAETISNGEAGCFMHGPTFMGNPLACAAANASLAILESGDWQQ
                     QVADIEVQLREQLAPARDAEMVADVRVLGAIGVVETTHPVNMAALQKFFVEQGVWIRP
                     FGKLIYLMPPYIILPQQLQRLTAAVNRAVQDETFFCQ"
     gene            38424..39464
                     /gene="bioB"
                     /locus_tag="RN951_000640"
     CDS             38424..39464
                     /gene="bioB"
                     /locus_tag="RN951_000640"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HDX2525691.1"
                     /translation="MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVST
                     LLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAW
                     KNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEF
                     YGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPES
                     VPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMC
                     FMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMT
                     PDTDEYYNAAAL"
     gene            39461..40615
                     /gene="bioF"
                     /locus_tag="RN951_000641"
     CDS             39461..40615
                     /gene="bioF"
                     /locus_tag="RN951_000641"
                     /EC_number="2.3.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-amino-7-oxononanoate synthase"
                     /protein_id="HDX2525692.1"
                     /translation="MSWQEKINAALDARRAADALRRRYPVAQGAGRWLVADDRQYLNF
                     SSNDYLGLSHHPQIIRAWQQGAEQFGIGSGGSGHVSGYSVVHQALEEELAEWLGYSRA
                     LLFISGFAANQAVIAAMMAKEDRIAADRLSHASLLEAASLSPSQLRRFAHNDVTHLAR
                     LLASPCPGQQMVVTEGVFSMDGDSAPLAEIQQVTQQHNGWLMVDDAHGTGVIGEQGRG
                     SCWLQKVKPELLVVTFGKGFGVSGAAVLCSSTVADYLLQFARHLIYSTSMPPAQAQAL
                     RASLAVIRSDEGDARREKLAALITRFRAGVQDLPFTLADSCSAIQPLIVGDNSRALQL
                     AEKLRQQGCWVTAIRPPTVPAGTARLRLTLTAAHEMQDIDRLLEVLHGNG"
     gene            40602..41357
                     /gene="bioC"
                     /locus_tag="RN951_000642"
     CDS             40602..41357
                     /gene="bioC"
                     /locus_tag="RN951_000642"
                     /EC_number="2.1.1.197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonyl-ACP O-methyltransferase BioC"
                     /protein_id="HDX2525693.1"
                     /translation="MATVNKQAIAAAFGRAAAHYEQHADLQRQSADALLAMLPQRKYT
                     HVLDAGCGPGWMSRHWRERHAQVTALDLSPPMLVQARQKDAADHYLAGDIESLPLATA
                     TFDLAWSNLAVQWCGNLSTALRELYRVVRPKGVVAFTTLVQGSLPELHQAWQAVDERP
                     HANRFLPPDEIEQSLNGVHYQHHIQPITLWFDDALSAMRSLKGIGATHLHEGRDPRIL
                     TRSQLQRLQLAWPQQQGRYPLTYHLFLGVIARE"
     gene            41350..42027
                     /gene="bioD"
                     /locus_tag="RN951_000643"
     CDS             41350..42027
                     /gene="bioD"
                     /locus_tag="RN951_000643"
                     /EC_number="6.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent dethiobiotin synthetase BioD"
                     /protein_id="HDX2525694.1"
                     /translation="MSKRYFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGS
                     EKTPEGLHNSDALALQRNSSLQLDYATVNPYTFAEPTSPHIISAQEGRPIESLVMSAG
                     LRALEQQADWVLVEGAGGWFTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTA
                     QVIQHAGLTLAGWVANDVTPPGKRHAEYMTTLTRMIPAPLLGEIPWLAENPENAATGK
                     YINLALL"
     gene            42606..44627
                     /gene="uvrB"
                     /locus_tag="RN951_000644"
     CDS             42606..44627
                     /gene="uvrB"
                     /locus_tag="RN951_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HDX2525695.1"
                     /translation="MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSG
                     KTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYV
                     PSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
                     LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFD
                     EEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLE
                     NNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGL
                     LVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYV
                     SATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVL
                     VTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLRE
                     GLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIG
                     ETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVP
                     MDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS"
     gene            complement(44819..45727)
                     /gene="yvcK"
                     /locus_tag="RN951_000645"
     CDS             complement(44819..45727)
                     /gene="yvcK"
                     /locus_tag="RN951_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HDX2525696.1"
                     /translation="MRNRTLADLDRVVALGGGHGLGRVLSSLSSLGSRLTGIVTTTDN
                     GGSTGRIRRSEGGIAWGDMRNCLNQLITEPSVASAMFEYRFGGNGELSGHNLGNLMLK
                     ALDHLSVRPLEAINLIRNLLKVDTHLIPMSEHPVDLMAIDDQGHEVYGEVNIDQLTTP
                     IQELLLTPNVPATREAVHAINEADLIIIGPGSFYTSLMPILLLKEIAQALRRTPAPMV
                     YIGNLGRELSLPAANLKLESKLAIMEQYVGKKVIDAVIVGPKVDVSAVKERIVIQEVL
                     EASDIPYRHDRQLLHNALEKALQALG"
     regulatory      45992..46136
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01055"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="molybdenum cofactor riboswitch; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="molybdenum cofactor"
                     /db_xref="RFAM:RF01055"
     gene            46124..47113
                     /gene="moaA"
                     /locus_tag="RN951_000646"
     CDS             46124..47113
                     /gene="moaA"
                     /locus_tag="RN951_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HDX2525697.1"
                     /translation="MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNK
                     GFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNG
                     YRLERDVASWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVK
                     VNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELL
                     RRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLF
                     GEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG"
     gene            47135..47647
                     /gene="moaB"
                     /locus_tag="RN951_000647"
     CDS             47135..47647
                     /gene="moaB"
                     /locus_tag="RN951_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein B"
                     /protein_id="HDX2525698.1"
                     /translation="MSQVSTEFIPTRIAILTVSNRRGEEDDTSGHYLRDSAQEAGHHV
                     VDKAIVKENRYAIRAQVSAWIASDDVQVVLITGGTGLTEGDQAPEALLPLFDREVEGF
                     GEVFRMLSFEEIGTSTLQSRAVAGVANKTLIFAMPGSTKACRTAWENIIAPQLDARTR
                     PCNFHPHLKK"
     gene            47650..48135
                     /gene="moaC"
                     /locus_tag="RN951_000648"
     CDS             47650..48135
                     /gene="moaC"
                     /locus_tag="RN951_000648"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HDX2525699.1"
                     /translation="MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMI
                     IDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETL
                     CRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEAD
                     D"
     gene            48128..48373
                     /gene="moaD"
                     /locus_tag="RN951_000649"
     CDS             48128..48373
                     /gene="moaD"
                     /locus_tag="RN951_000649"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase sulfur carrier subunit"
                     /protein_id="HDX2525700.1"
                     /translation="MIKVLFFAQVRELVGTDATEVAADFPTVEALRQHMAAQSDRWAL
                     ALEDGKLLAAVNQTLVSFDHPLTDGDEVAFFPPVTGG"
     gene            48375..48827
                     /gene="moaE"
                     /locus_tag="RN951_000650"
     CDS             48375..48827
                     /gene="moaE"
                     /locus_tag="RN951_000650"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase catalytic subunit MoaE"
                     /protein_id="HDX2525701.1"
                     /translation="MAETKIVVGPQPFSVGEEYPWLAERDEDGAVVTFTGKVRNHNLG
                     DSVNALTLEHYPGMTEKALAEIVDEARNRWPLGRVTVIHRIGELWPGDEIVFVGVTSA
                     HRSSAFEAGQFIMDYLKTRAPFWKREATPEGDRWVEARESDQQAAKRW"
     gene            48964..49668
                     /locus_tag="RN951_000651"
     CDS             48964..49668
                     /locus_tag="RN951_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HDX2525702.1"
                     /translation="MDRFPRSDSIVQPRAGLQTYMAQVYGWMTVGLLLTAFVAWYAAN
                     SAAVMELLFTNRVFLIGLIIAQLALVIVLSAMIQKLSAGVTTMLFMLYSALTGLTLSS
                     IFIVYTAASIASTFVVTAGMFGAMSLYGYTTKRDLSGFGNMLFMALIGIVLASLVNFW
                     LKSEALMWAVTYIGVIVFVGLTAYDTQKLKNMGEQIDTRDTSNLRKYSILGALTLYLD
                     FINLFLMLLRIFGNRR"
     gene            49873..50586
                     /locus_tag="RN951_000652"
     CDS             49873..50586
                     /locus_tag="RN951_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706665.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HDX2525703.1"
                     /translation="MESYSQNSNKLDFQHEARILNGIWLITALGLVATAGLAWGAKYL
                     EITATKYDSPPMYVAIGLLLLCMYGLSKDINKINAAIAGVIYLFLLSLVAIVVASLVP
                     VYAIIIVFSTAGAMFLISMLAGLLFNVDPGSHRFIIMMTLTGLALVIIVNAALMSERP
                     IWVISCLMIVLWSGIISHGRNKLLELAGKCHSEELWSPVRCAFTGALTLYYYFIGFFG
                     ILAAIAITLVWQRHTRFFH"
     gene            complement(50622..51578)
                     /locus_tag="RN951_000653"
     CDS             complement(50622..51578)
                     /locus_tag="RN951_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0104 family protein"
                     /protein_id="HDX2525704.1"
                     /translation="MSKSHPRWRLAKKILTWLFFIAVIVLLVVYAKKVDWEEVWKVIR
                     DYNRVALLSAVGLVVVSYLIYGCYDLLARFYCGHKLAKRQVMLVSFICYAFNLTLSTW
                     VGGIGMRYRLYSRLGLPGSTIMRIFSLSITTNWLGYILLAGIIFTAGVVELPDHWYVD
                     QTTLRILGIGLLMIIAVYLWFCAFAKHRHMTIKGQKLVLPSWKFALAQMLISSVNWMV
                     MGAIIWLLLGQSVNYFFVLGVLLVSSIAGVIVHIPAGIGVLEAVFIALLAGEHTSKGT
                     IIAALLAYRVLYYFIPLLLALICYLLLESQAKKLRAKNEAAM"
     gene            complement(51578..52819)
                     /gene="clsB"
                     /locus_tag="RN951_000654"
     CDS             complement(51578..52819)
                     /gene="clsB"
                     /locus_tag="RN951_000654"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase ClsB"
                     /protein_id="HDX2525705.1"
                     /translation="MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFE
                     DDVGKQLHAALLAAAQRGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLF
                     GMRTNVFRRMHRKIVVIDARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDIL
                     QFELENLPGQSAARRWWRRHHKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQ
                     ARREVIIANAYFFPGYRFLHALRKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVK
                     GGVQVFEYRRRPLHGKVALMDDHWATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRD
                     NLNGIIAADCQQVDETMLPKRTWWNLTKSVLAFHFLRHFPALVGWLPAHTPRLAQVDP
                     PAQPTMETQDRVETENTGVKP"
     gene            complement(52816..53577)
                     /locus_tag="RN951_000655"
     CDS             complement(52816..53577)
                     /locus_tag="RN951_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDX2525706.1"
                     /translation="MPDQTQQFSFKVLTINIHKGFTAFNRRFILPELRDAVRTVSADI
                     VCLQEVMGAHEVHPLHVENWPDTSHYEFLADTMWSDFAYGRNAVYPEGHHGNAVLSRY
                     PIEHYENRDVSVDGAEKRGVLYCRIVPPMTGKAIHVMCVHLGLREAHRQAQLAMLAEW
                     VNELPDGEPVLVAGDFNDWRQKANHPLKVQAGLDEIFTRAHGRPARTFPVQFPLLRLD
                     RIYVKNASASAPTALPLRTWRHLSDHAPLSAEIHL"
     gene            53710..54120
                     /locus_tag="RN951_000656"
     CDS             53710..54120
                     /locus_tag="RN951_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhQ family protein"
                     /protein_id="HDX2525707.1"
                     /translation="MKWQQRVRVATGLSCWQIMLHLLVVALLVVGWMSKTLVHVGVGL
                     CALYCVTVVMMLVFQRHPEQRWREVADVLEELTTTWYFGAALIVLWLLSRVLENNFLL
                     AIAGLAILAGPAVVSLLAKDKKLHHLTSKHRVRR"
     gene            complement(54082..55188)
                     /locus_tag="RN951_000657"
     CDS             complement(54082..55188)
                     /locus_tag="RN951_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX2525708.1"
                     /translation="MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFAATLE
                     VTNATIAIYDEDNGEHSVELTQRFARASAFTHVLLLKSPQEIRPTIDTQKALLLVRFP
                     ADFSRKLDTFQTAPLQLILDGRNSNSAQIAANYLQQIVKNYQQELLEGKPKPNNSELV
                     VRNWYNPNLDYKWFVVPSLIAMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTWQI
                     FIGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLISS
                     LCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQNLTWINPIRHFTDITKQIYLK
                     DASLDIVWNSLWPLLVITATTGSAAYAMFRRKVM"
     gene            complement(55199..56332)
                     /locus_tag="RN951_000658"
     CDS             complement(55199..56332)
                     /locus_tag="RN951_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX2525709.1"
                     /translation="MSNPILSWRRVRALCVKETRQIVRDPSSWLIAVVIPLLLLFIFG
                     YGINLDSSKLRVGILLEQRSEAALDFTHTMTGSPYIDATISDNRQELIAKMQAGKIRG
                     LVVIPVDFAEQMERANATAPIQVITDGSEPNTANFVQGYVEGIWQIWQMQRAEDNGQT
                     FEPLIDVQTRYWFNPAAISQHFIIPGAVTIIMTVIGAILTSLVVAREWERGTMEALLS
                     TEITRTELLLCKLIPYYFLGMLAMLLCMLVSVFILGVPYRGSLLILFFISSLFLLSTL
                     GMGLLISTITRNQFNAAQVALNAAFLPSIMLSGFIFQIDSMPAVIRAVTYIIPARYFV
                     STLQSLFLAGNIPVVLVVNVLFLIASAVMFIGLTWLKTKRRLD"
     gene            complement(56325..58061)
                     /locus_tag="RN951_000659"
     CDS             complement(56325..58061)
                     /locus_tag="RN951_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415315.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX2525710.1"
                     /translation="MNDAVITLNGLEKRFPGMDKPAVAPLDCTIHAGYVTGLVGPDGA
                     GKTTLMRMLAGLLKPDSGSATVIGFDPIKNDGALHAVLGYMPQKFGLYEDLTVMENLN
                     LYADLRSVTGEARKQTFARLLEFTSLGPFTGRLAGKLSGGMKQKLGLACTLVGEPKVL
                     LLDEPGVGVDPISRRELWQMVHELAGEGMLILWSTSYLDEAEQCRDVLLMNEGELLYQ
                     GGPKALTQTMAGRSFLMTSPHEGNRKLLQRALKLPQVSDGMIQGKSVRLILKKEATPD
                     DIRHADGMPEININETTPRFEDAFIDLLGGAGTSESPLGAILHTVEGTPGETVIEAKE
                     LTKKFGDFAATDHVNFAVKRGEIFGLLGPNGAGKSTTFKMMCGLLVPTSGQALVLGMD
                     LKESSGKARQHLGYMAQKFSLYGNLTVEQNLRFFSGVYGLRGRAQNEKISRMSEAFGL
                     KSIASHATDELPLGFKQRLALACSLMHEPDILFLDEPTSGVDPLTRREFWLHINSMVE
                     KGVTVMVTTHFMDEAEYCDRIGLVYRGKLIASGTPDDLKAQSANDEQPDPTMEQAFIQ
                     LIHDWDKEHSNE"
     gene            complement(58054..59049)
                     /gene="hlyD"
                     /locus_tag="RN951_000660"
     CDS             complement(58054..59049)
                     /gene="hlyD"
                     /locus_tag="RN951_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308900.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein HlyD"
                     /protein_id="HDX2525711.1"
                     /translation="MKKPVVIGLAVVVLAAVVAGGYWWYQSRQDNGLTLYGNVDIRTV
                     NLSFRVGGRVESLAVDEGDAIKAGQVLGELDHKPYEIALMQAKAGVSVAQAQYDLMLA
                     GYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQAT
                     LKSAQDKLRQYRSGNREQDIAQAKASLEQAQAQLAQAELNLQDSTLIAPSDGTLLTRA
                     VEPGTVLNEGGTVFTVSLTRPVWVRAYVDERNLDQAQPGRKVLLYTDGRPDKPYHGQI
                     GFVSPTAEFTPKTVETPDLRTDLVYRLRIVVTDADDALRQGMPVTVQFGDEAGHE"
     gene            complement(59052..59723)
                     /gene="cecR"
                     /locus_tag="RN951_000661"
     CDS             complement(59052..59723)
                     /gene="cecR"
                     /locus_tag="RN951_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415317.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CecR"
                     /protein_id="HDX2525712.1"
                     /translation="MNNPAMTIKGEQAKKQLIAAALAQFGEYGMNATTREIAAQAGQN
                     IAAITYYFGSKEDLYLACAQWIADFIGEQFRPHAEEAERLFAQPQPDRAAIRELILRA
                     CRNMIKLLTQDDTVNLSKFISREQLSPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDA
                     NDTRMILHTHALIGEILAFRLGKETILLRTGWTAFDEEKTELINQTVTCHIDLILQGL
                     SQRSL"
     gene            59952..61316
                     /gene="rhlE"
                     /locus_tag="RN951_000662"
     CDS             59952..61316
                     /gene="rhlE"
                     /locus_tag="RN951_000662"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlE"
                     /protein_id="HDX2525713.1"
                     /translation="MSFDSLGLSPDILRAVAEQGYREPTPIQQQAIPAVLEGRDLMAS
                     AQTGTGKTAGFTLPLLQHLITRQPHAKGRRPVRALILTPTRELAAQIGENVRDYSKYL
                     NIRSLVVFGGVSINPQMMKLRGGVDVLVATPGRLLDLEHQNAVKLDQVEILVLDEADR
                     MLDMGFIHDIRRVLTKLPAKRQNLLFSATFSDDIKALAEKLLHNPLEIEVARRNTASD
                     QVTQHVHFVDKKRKRELLSHMIGKGNWQQVLVFTRTKHGANHLAEQLNKDGIRSAAIH
                     GNKSQGARTRALADFKSGDIRVLVATDIAARGLDIEELPHVVNYELPNVPEDYVHRIG
                     RTGRAAATGEALSLVCVDEHKLLRDIEKLLKKEIPRIAIPGYEPDPSIKAEPIQNGRQ
                     QRGGGGRGQGGGRGQQQPRRGEGGAKSASAKPAEKPSRRLGDAKPAGEQQRRRRPRKP
                     AAAQ"
     gene            complement(61548..62030)
                     /gene="ybiA"
                     /locus_tag="RN951_000663"
     CDS             complement(61548..62030)
                     /gene="ybiA"
                     /locus_tag="RN951_000663"
                     /EC_number="3.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-glycosidase YbiA"
                     /protein_id="HDX2525714.1"
                     /translation="MPVRAQRIQHVMQDTIINFYSTSDDYGDFSNFAAWPIKVDGKTW
                     PTSEHYFQAQKFLDEKYREEIRRVSSPMVAARMGRDRSKPLRKNWESVKEQVMRKALR
                     AKFEQHAELRALLLATAPAKLVEHTENDAYWGDGGHGKGKNRLGYLLMELREQLAIEK
                     "
     gene            62150..64300
                     /gene="dinG"
                     /locus_tag="RN951_000664"
     CDS             62150..64300
                     /gene="dinG"
                     /locus_tag="RN951_000664"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase DinG"
                     /protein_id="HDX2525715.1"
                     /translation="MALTAALKAQIAAWYKALQEQIPDFIPRAPQRQMIADVAKTLAG
                     EEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIYSKDLPLLKK
                     IIPDLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNNQEEQKRCAKLK
                     GDLDTYKWDGLRDHTDIAIDDDLWRRLSTDKASCLNRNCYYYRECPFFVARREIQEAE
                     VVVANHALVMAAMESEAVLPDPKNLLLVLDEGHHLPDVARDALEMSAEITAPWYRLQL
                     DLFTKLVATCMEQFRPKTIPPLAIPERLNAHCEELYELIASLNNILNLYMPAGQEAEH
                     RFAMGELPDEVLEICQRLAKLTEMLRGLAELFLNDLSEKTGSHDIVRLHRLILQMNRA
                     LGMFEAQSKLWRLASLAQSSGAPVTKWATREEREGQLHLWFHCVGIRVSDQLERLLWR
                     SIPHIIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVE
                     PSIDNEEQHIAEMAAFFRKQVESKKHLGMLVLFASGRAMQRFLDYVTDLRLMLLVQGD
                     QPRYRLVELHRKRVANGERSVLVGLQSFAEGLDLKGDLLSQVHIHKIAFPPIDSPVVI
                     TEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNYGKR
                     LLDALPVFPIEQPEVPEGIVKKKEKTKSPRRRRR"
     gene            64328..65290
                     /gene="ybiB"
                     /locus_tag="RN951_000665"
     CDS             64328..65290
                     /gene="ybiB"
                     /locus_tag="RN951_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein YbiB"
                     /protein_id="HDX2525716.1"
                     /translation="MDYRKIIKEIGRGKNHARDLDRDTARGLYAHMLNGEVPDLELGG
                     VLIALRIKGEGEAEMLGFYEAMQNHTIKLTPPAGKPMPIVIPSYNGARKQANLTPLLA
                     ILLHKLGFPVVVHGVSEDPTRVLTETIFELMGITPTLHGGQAQAKLDEHQPVFMPVGA
                     FCPPLEKQLAMRWRMGVRNSAHTLAKLATPFAEGEALRLSSVSHPEYIGRVAKFFSDI
                     GGRALLMHGTEGEVYANPQRCPQINLIDREGMRVLYEKQDTAGSELLPQAKDPETTAQ
                     WIERCLAGSEPIPESLKIQMACCLVATGEAATISDGLARVNQAF"
     gene            65431..66516
                     /gene="hcxB"
                     /locus_tag="RN951_000666"
     CDS             65431..66516
                     /gene="hcxB"
                     /locus_tag="RN951_000666"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxycarboxylate dehydrogenase HcXB"
                     /protein_id="HDX2525717.1"
                     /translation="MESGHRFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAG
                     HDSHGIGMIPSYVRSWSQGHLQINHHAKTVKEAGAAVTLDGDRAFGQVAAHEAMALGI
                     EKAHQHGIAAVALHNSHHIGRIGYWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRF
                     GTNPFCVVFPRKDNFPLLLDYATSAIAFGKTRVAWHKGVPVPPGCLIDVNGVPTTNPA
                     VMQESPLGSLLTFAEHKGYALAAMCEILGGALSGGKTTHQETLQTSPDAILNCMTTII
                     INPELFGAPDCNAQTEAFAEWVKASPHDDDKPILLPGEWEVNTRRERQKQGIPLDAGS
                     WQAICDAARQIGMPEETLQAFCQQLAS"
     gene            complement(66745..67005)
                     /locus_tag="RN951_000667"
     CDS             complement(66745..67005)
                     /locus_tag="RN951_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDX2525718.1"
                     /translation="MKTINTVVAAMALSTLSFGVFAAEPVTASQAQNMNKIGVVSADG
                     ASTLDALEAKLAEKAAAAGASGYSITSATNNNKLSGTAVIYK"
     gene            complement(67270..67536)
                     /gene="ybiI"
                     /locus_tag="RN951_000668"
     CDS             complement(67270..67536)
                     /gene="ybiI"
                     /locus_tag="RN951_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-type zinc finger protein YbiI"
                     /protein_id="HDX2525719.1"
                     /translation="MASGWANDDAVNEQINSTIEDAIARARGEIPRGESLDECEECGA
                     PIPQARREAIPGVRLCIHCQQEKDLQKPAYTGYNRRGSKDSQLR"
     gene            complement(67610..68287)
                     /gene="ybiX"
                     /locus_tag="RN951_000669"
     CDS             complement(67610..68287)
                     /gene="ybiX"
                     /locus_tag="RN951_000669"
                     /EC_number="1.14.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415325.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKHD-type hydroxylase YbiX"
                     /protein_id="HDX2525720.1"
                     /translation="MMYHIPGVLSPQDVARFREQLEQAEWVDGRVTTGAQGAQVKNNQ
                     QVDTRSTLYAALQNEVLNAVNQHALFFAAALPRTLSTPLFNRYQNNETYGFHVDGAVR
                     SHPQNGWMRTDLSATLFLSDPQSYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCV
                     TPVTRGVRVASFMWIQSMIRDDKKRAMLFELDNNIQSLKSRYGESEEILSLLNLYHNL
                     LREWSEI"
     gene            complement(68329..70611)
                     /locus_tag="RN951_000670"
                     /pseudo
     CDS             complement(68329..70611)
                     /locus_tag="RN951_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415326.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="catecholate siderophore receptor Fiu"
     gene            complement(70876..71136)
                     /locus_tag="RN951_000671"
     CDS             complement(70876..71136)
                     /locus_tag="RN951_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415327.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDX2525721.1"
                     /translation="MKKCLTLLIATVLSGISLTAYAAQPMSNLDSGQLRPAGTVSATG
                     ASNLSDLEDKLAEKAREQGAKGYVINSAGGNDQMFGTATIYK"
     gene            71412..72338
                     /gene="rlmF"
                     /locus_tag="RN951_000672"
     CDS             71412..72338
                     /gene="rlmF"
                     /locus_tag="RN951_000672"
                     /EC_number="2.1.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415328.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(1618)-N(6))-methyltransferase
                     RlmF"
                     /protein_id="HDX2525722.1"
                     /translation="MSAQKPGLHPRNRHHSRYDLATLCQVNPELRQFLTLTPAGEQSV
                     DFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPVPGRADYIHHLADLLAEASGTIP
                     ANASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISSNPGLNRAIRLR
                     RQKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGG
                     QQQELWCEGGEVTFIKKMIEESKGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVV
                     KKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR"
     gene            complement(72335..74560)
                     /gene="ybiO"
                     /locus_tag="RN951_000673"
     CDS             complement(72335..74560)
                     /gene="ybiO"
                     /locus_tag="RN951_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415329.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel protein"
                     /protein_id="HDX2525723.1"
                     /translation="MRWILFILFCLLGAPAHAVSIPGVTTTTTTDSTTEPAPEPDIEQ
                     KKAAYGALADVLDNDTSRKELIDQLRTVAATPPAEPVPKIVPPTLVEEQTVLQKVTEV
                     SRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFSMLAVLVFGFYWLIRLCAL
                     PLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQVLSDNLNAGSRT
                     IAFQQSLFLNAFALIEFFKAVLRLIFCPNVAELRPFTIQDESARYWSRRLSWLSSLIG
                     YGLIVAVPIISNQVNVQIGALANVIIMLCMTVWALYLIFRNKKEITQHLLNFAEHSLA
                     FFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSG
                     MFSRWLAKTITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLSAWGLFD
                     FWNWLQNGAGQKTVDILIRIALILFFSAVGWTVLASLIENRLASDIHGRPLPSARTRT
                     LLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGV
                     FIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGI
                     GSVVANYDVDRHEDADKANQALKDAVAELMENEEIRGLIIGEPNFAGIVGLSNTAFTL
                     RVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTYQVLPAPGATPAEPLPPGEPT
                     L"
     gene            complement(74821..75543)
                     /gene="glnQ"
                     /locus_tag="RN951_000674"
     CDS             complement(74821..75543)
                     /gene="glnQ"
                     /locus_tag="RN951_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter ATP-binding protein
                     GlnQ"
                     /protein_id="HDX2525724.1"
                     /translation="MIEFKNVSKHFGPTQVLHNIDLNIAQGEVVVIIGPSGSGKSTLL
                     RCINKLEEITSGDLIVDGLKVNDPKVDERLIRQEAGMVFQQFYLFPHLTALENVMFGP
                     LRVRGANKEEAEKLARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKMMLF
                     DEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDG
                     NPQVLIKNPPSQRLQEFLQHVS"
     gene            complement(75540..76199)
                     /gene="glnP"
                     /locus_tag="RN951_000675"
     CDS             complement(75540..76199)
                     /gene="glnP"
                     /locus_tag="RN951_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015367581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter permease GlnP"
                     /protein_id="HDX2525725.1"
                     /translation="MQFDWSAIWPAIPLLIEGAKMTLWISVLGLAGGLVIGLLAGFAR
                     TFGGWIANHVALVFIEVIRGTPIVVQVMFIYFALPMAFNDLRIDPFTAAVVTIMINSG
                     AYIAEITRGAVLSIHKGFREAGLALGLSRWETIRYVILPLALRRMLPPLGNQWIISIK
                     DTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVFYLIITLVLSFILRRLERRMKI
                     L"
     gene            complement(76338..77084)
                     /gene="glnH"
                     /locus_tag="RN951_000676"
     CDS             complement(76338..77084)
                     /gene="glnH"
                     /locus_tag="RN951_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter substrate-binding
                     protein GlnH"
                     /protein_id="HDX2525726.1"
                     /translation="MKSVLKVSLAALTLAFAVSSHAADKKLVVATDTAFVPFEFKQGD
                     KYVGFDVDLWAAIAKELKLDYELKPMDFSGIIPALQTKNVDLALAGITITDERKKAID
                     FSDGYYKSGLLVMVKANNNDVKSVKDLDGKVVAVKSGTGSVDYAKANIKTKDLRQFPN
                     IDNAYMELGTNRADAVLHDTPNILYFIKTAGNGQFKAVGDSLEAQQYGIAFPKGSDEL
                     RDKVNGALKTLRENGTYNEIYKKWFGTEPK"
     gene            complement(77488..77991)
                     /gene="dps"
                     /locus_tag="RN951_000677"
                     /gene_synonym="pexB"
     CDS             complement(77488..77991)
                     /gene="dps"
                     /locus_tag="RN951_000677"
                     /gene_synonym="pexB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001730644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein Dps"
                     /protein_id="HDX2525727.1"
                     /translation="MSTAKLVKSKATNLLYTRNDVSDSEKKATVELLNRQVIQFIDLS
                     LITKQAHWNMRGANFIAVHEMLDGFRTALIDHLDTMAERAVQLGGVALGTTQVINSKT
                     PLKSYPLDIHNVQDHLKELADRYAIVANDVRKAIGEAKDDDTADILTAASRDLDKFLW
                     FIESNIE"
BASE COUNT        18726 a        19723 c        20807 g        18928 t
ORIGIN      
        1 tcctgaaact ctgcgtcgta ttagccagtg accaaaaaaa gaattaaggt caaccgtgct
       61 gtttttgctt cgtctctttt tatctttaat tgccaaccga aactaatttc agccttataa
      121 ctcacacatt ttaaacataa atgtcactaa agttacctta ttgaaacatg attaacataa
      181 tttgtaggaa ttgatattta tcaatgtata agtcttggaa atgggcatca aaaagagata
      241 aattgttctc gatcaaattg gctgaaaggc ggtaatttag ctataaattg atcaccgtcg
      301 aaaaatgcaa atttgcttca acaaaaacct gtttattgta aggattttgc ggcgtaatat
      361 atacgtggga tcaatttgag tttttattaa catgtttgca acctttcttt acgccgtttt
      421 tgtgtgcatt cacatggtat gatgaaagtg ttcaaacaaa tttctattgg ggcatgcgtg
      481 tgaccctttc taacggggtt cactctcgga gtcttcatgc gatgagcaag gagtcatgat
      541 gttagatata gtcgaactgt cgcgcttaca gtttgccttg accgcgatgt accacttcct
      601 ttttgtgcca ctgacgctcg gtatggcgtt cctgctggcc attatggaaa cggtctacgt
      661 cctctccggc aaacagattt ataaagatat gaccaagttc tggggcaagt tgtttggtat
      721 caacttcgct ctgggtgtgg ctaccggtct gaccatggag ttccagttcg ggactaactg
      781 gtcttactat tcccactatg taggggatat cttcggtgcg ccgctggcaa tcgaaggtct
      841 gatggccttc ttcctcgaat ccacctttgt aggtctgttc ttcttcggtt gggatcgtct
      901 gggtaaagtt cagcatatgt gtgtcacctg gctggtggcg ctcggttcaa acctgtccgc
      961 actgtggatt ctggttgcga acggctggat gcaaaaccca atcgcgtccg atttcaactt
     1021 tgaaactatg cgtatggaga tggtgagctt ctccgagctg gtgcttaacc cggttgctca
     1081 ggtgaaattc gttcacactg tagcgtctgg ttatgtgact ggcgcgatgt tcatcctcgg
     1141 tatcagcgca tggtatatgc tgaaaggtcg tgacttcgcc ttcgctaaac gctcctttgc
     1201 tatcgctgcc agcttcggta tggctgctgt tctgtctgtt attgttctgg gtgatgaatc
     1261 cggctacgaa atgggcgacg tgcagaaaac caaactggct gctattgaag ccgagtggga
     1321 aacgcaacct gcgcctgctg cctttactct gttcggcatt cctgatcagg aagaggagac
     1381 gaacaaattt gcgattcaga tcccttacgc actgggcatc attgcaacgc gttccgtgga
     1441 taccccggtt atcggcctga aagagctgat ggtgcagcat gaagaacgca ttcgtaacgg
     1501 gatgaaggcg tactctctgc tcgaacaact gcgttctggt tctaccgacc aggcggttcg
     1561 tgaccagttc aatagcatga agaaagacct cggttacggt ctgctgctga aacgctatac
     1621 gccaaacgtg gctgatgcga ctgaagcgca gattcaacag gcaaccaaag actccatccc
     1681 gcgtgtagcg ccgctgtact ttgcgttccg tatcatggtg gcgtgtggct tcctgcttct
     1741 ggcaatcatc gcgctctctt tctggagtgt catccgcaac cgcattggcg agaaaaaatg
     1801 gcttctgcgc gccgcgctgt acggtattcc gctgccgtgg attgctgtag aagcgggctg
     1861 gttcgtggct gaatatggcc gccaaccgtg ggctatcggt gaagtgctgc cgacagctgt
     1921 ggcgaactcg tcactgaccg caggcgatct catcttctca atggtgctga tttgcggcct
     1981 gtataccctg ttcctggtgg cagaattgtt cttaatgttc aagtttgcac gcctcggccc
     2041 aagcagcctg aaaaccggtc gctatcactt tgagcagtct tccacgacta ctcagccggc
     2101 acgctaagac aggagtcgtc aaatgatcga ttatgaagta ttgcgtttta tctggtggct
     2161 gctggttggc gttctgctga ttggttttgc agtcactgac ggtttcgaca tgggggtggg
     2221 catgctcacc cgtttcctcg gtcgtaacga caccgagcgt cgaattatga ttaactccat
     2281 tgcaccacac tgggacggta accaggtttg gctgatcacc gcgggcggcg cactctttgc
     2341 tgcctggccg atggtctatg ccgctgcgtt ctccggcttc tatgtggcga tgatcctcgt
     2401 gctggcgtct ttgttcttcc gtccggtcgg ttttgactac cgctccaaga ttgaagaaac
     2461 ccgctggcgt aacatgtggg actggggcat cttcattggt agcttcgttc cgccgctggt
     2521 aattggtgta gcgttcggta acctgttgca gggcgtaccg ttcaacgttg atgaatatct
     2581 gcgtctgtac tacaccggta acttcttcca gttgcttaac ccgttcggcc tgctggcagg
     2641 cgtggtgagc gtagggatga tcattactca gggcgcaacc tatctgcaaa tgcgtaccgt
     2701 gggcgaactg cacctgcgta cccgtgcaac ggctcaggtg gctgcgctgg tgacactggt
     2761 ctgtttcgca ctggctggcg tatgggtgat gtacggtatc gatggttatg tcgtgaaatc
     2821 gacaatggac cattacgcag cctctaaccc actgaataaa gaagtggttc gtgaagctgg
     2881 cgcatggctg gttaacttca acaacacgcc aattctgtgg gctattccgg cactgggtgt
     2941 ggttctgccg ctgctgacca tcctgactgc acgtatggat aaagccgcgt gggcgtttgt
     3001 gttctcctcc ctgacgctgg cctgcatcat cctgacagcc ggtatcgcaa tgttcccgtt
     3061 tgtgatgccg tccagcacca tgatgaacgc aagtctgaca atgtgggatg caacttccag
     3121 ccagctgacg cttaacgtca tgacctgggt tgcggtggtt ctggtaccga tcattctgct
     3181 ctacaccgcc tggtgttact ggaaaatgtt cggtcgtatc accaaagaag atattgaacg
     3241 taacacccac tctctgtact aagtaaggag ctaaaaatgt ggtatttcgc atggattctg
     3301 ggaacgcttc ttgcctgttc gtttggggta atcaccgcgc tggcgcttga acacgtcgaa
     3361 tcaggcaaag ccggtcaaga agacatctga tgagtaagat tatcgcgact ttgtatgcgg
     3421 taatggacaa gcgccccctg cgggcgcttt ccttcgtgat ggcgcttctg ttagcaggat
     3481 gtatgttttg ggacccatct cgttttgccg cgaagaccag tgaactggaa atctggcatg
     3541 gtttattgct gatgtgggcc gtctgtgctg gtgtgattca cggcgtgggc tttcgtccgc
     3601 agaaggttct ttggcaaggg attttttgcc cattgcttgc cgatattgtt ctcattgtcg
     3661 ggctgatttt cttcttcttt taaatcagaa ttctctttaa aaaattatgg gccgctccag
     3721 gcccataaat ttttacgctc ccttaacttg ccctcattcc caaacctcaa tcgcgcgcgt
     3781 atagtagcag cgtttaaaag ctctaacttt tgttgcatta ccgggatgta aagtgaatac
     3841 aacgctgttt cgatggccgg ttcgcgtcta ctatgaagat accgatgccg gtggtgtggt
     3901 gtaccacgcc agttacgtcg ctttttatga aagagcacgc acagagatgc tgcgtcatca
     3961 tcacttcagt cagcaggcgc tgatggctga acgcgttgcc tttgtggtac gtaaaatgac
     4021 ggtggaatat tacgcacctg cgcggctcga cgatatgctc gaaatacaga ctgaaataac
     4081 atcaatgcgt ggcacctctt tggttttcac gcaacgtatt gtcaacgccg agaatacttt
     4141 gctgaatgaa gcagaggttc tggttgtttg cgttgaccca ctcaaaatga agcctcgtgc
     4201 gcttcccaag tctattgtcg cggagtttaa gcagtgactg acatgaatat ccttgatttg
     4261 ttcctgaagg ctagccttct ggttaaactt atcatgttga ttttgattgg tttttcaatc
     4321 gcatcttggg ccattattat ccagcggacc cgtattctta acgcagcggc gcgcgaagcc
     4381 gaagcgtttg aagataaatt ctggtctgga atcgaactct ctcgcctcta tcaagagagc
     4441 caggggaaac gggataatct gactggttcg gaacaaatct tttacagcgg gttcaaagag
     4501 tttgtgcgcc tgcatcgtgc caatagccat gcgccggaag ccgtagtgga aggggcgtcg
     4561 cgtgctatgc gtatctccat gaaccgtgaa cttgaaaatc tggaaacgca cattccgttc
     4621 ctcggtacgg ttggctccat cagcccgtat attggtctgt ttggtacggt ctgggggatc
     4681 atgcacgcct ttatcgccct cggggcggta aaacaagcaa cactgcaaat ggttgcgccc
     4741 ggtatcgcag aagcgttgat tgcgactgca attggtctgt ttgccgctat cccggcagtt
     4801 atggcctaca accgcctcaa ccagcgcgta aacaaactgg aactgaatta cgacaacttt
     4861 atggaagagt ttaccgcgat tctgcaccgc caggcgttta ccgttagcga gagcaacaag
     4921 gggtaagcca tggccagagc gcgtggacga ggtcgtcgcg atctcaagtc cgaaatcaac
     4981 attgtaccgt tgctggacgt actgctggtg ctgttgctga tctttatggc gacagcgccc
     5041 atcatcaccc agagcgtgga ggtcgatctg ccagacgcta ctgaatcaca ggcggtgagc
     5101 agtaacgata atccgccagt gattgttgaa gtgtctggta ttggtcagta caccgtggtg
     5161 gttgagaaag atcgcctgga gcgtttacca ccagagcagg tggtggcgga agtgtccagc
     5221 cgtttcaagg ccaacccgaa aacggtcttt ctgatcggtg gcgcaaaaga tgtgccttac
     5281 gatgaaataa ttaaagcact gaacttgtta catagtgcgg gtgtgaaatc ggttggttta
     5341 atgacgcagc ctatctaaac atctgcgttt cccttgcttg aaagagagcg ggtaacaggc
     5401 gaacagtttt tggaaaccga gagtgtcaaa ggcaaccgaa caaaacgaca agctcaagcg
     5461 ggcgataatt atttcagcag tgctgcatgt catcttattt gcggcgctga tctggagttc
     5521 gttcgatgag aatatagaag cttcagccgg aggcggcggt ggttcgtcca tcgacgctgt
     5581 catggttgat tcaggtgcgg tagttgagca gtacaaacgc atgcaaagcc aggaatcaag
     5641 cgcgaagcgt tctgatgaac agcgcaagat gaaggaacag caggctgctg aagaactgcg
     5701 tgagaaacaa gcggctgaac aggaacgcct gaagcaactt gagaaagagc ggttagcggc
     5761 tcaggagcag aaaaagcagg ctgaagaagc cgcaaaacag gccgagctaa agcagaagca
     5821 agctgaagag gcggcagcga aagcggcggc agatgctaaa gcgaaggccg aagcagatgc
     5881 taaagctgcg gaagaagcag cgaagaaagc ggctgcagac gcaaagaaaa aagcagaagc
     5941 agaagccgcc aaagccgcag ccgaagcgca gaaaaaagcc gaggcagccg ctgcggcact
     6001 gaagaagaaa gcggaagcgg cagaagcagc tgcagctgaa gcaagaaaga aagcggcaac
     6061 tgaagctgct gaaaaagcca aagcagaagc tgagaagaaa gcggctgctg aaaaggctgc
     6121 agctgataag aaagcggcag cagagaaagc tgcagccgac aaaaaagcag cagaaaaagc
     6181 ggctgctgaa aaggcagcag ctgataagaa agcagcggca gaaaaagccg ccgcagacaa
     6241 aaaagcggca gcggcaaaag ctgcagctga aaaagccgct gcagcaaaag cggccgcaga
     6301 ggcagatgat attttcggtg agctaagctc tggtaagaat gcaccgaaaa cggggggagg
     6361 ggcgaaaggg aacaatgctt cgcctgccgg gagtggtaat actaaaaaca atggcgcatc
     6421 aggggccgat atcaataact atgccgggca gattaaatct gctatcgaaa gtaagttcta
     6481 tgacgcatcg tcctatgcag gcaaaacctg tacgctgcgc ataaaactgg cacccgatgg
     6541 tatgttactg gatatcaaac ctgaaggtgg cgatcccgca ctttgtcagg ctgcgttggc
     6601 agcagctaaa cttgcgaaga tcccgaaacc accaagccag gcagtatatg aagtgttcaa
     6661 aaacgcgcca ttggacttca aaccgtaatc gcgatgttga ctgttcggac ggtcaacatc
     6721 aggcaccggt tgccacgggg ttctggtagt tttgtgtatt ttagtttgtt aacattctgc
     6781 taaattatcg tgggccatcg gtccagataa gggagatatg atgaagcagg cattacgagt
     6841 agcatttggt tttctcatac tgtgggcatc agttctgcat gctgaagtcc gcattgtgat
     6901 cgacagcggt gtagattccg gtcgtcctat tggtgttgtt cctttccagt gggcggggcc
     6961 tggtgcggca cctgaagata ttggcggcat cgttgctgct gacttgcgta acagcggtaa
     7021 atttaatccg ttagatcgcg ctcgtctgcc acagcagccg ggtagtgcgc aggaagtaca
     7081 accagctgca tggtccgcac tgggcattga cgctgtagtt gtcggtcagg tcactccgaa
     7141 tccggatggt tcttacaatg ttgcttatca acttgttgac actggcggcg caccgggtac
     7201 tgtacttgct cagaactcgt acaaagtgaa caagcagtgg ctgcgttatg ctggtcatac
     7261 cgccagtgat gaagtgtttg aaaaactgac cggcattaaa ggtgcgttcc gtactcgtat
     7321 tgcctacgtt gttcagacca acggcggtca gttcccgtat gaactgcgcg tatctgacta
     7381 tgacggttac aaccagtttg tcgttcaccg ttcaccgcag ccgctgatgt ctccggcgtg
     7441 gtcaccagac ggttctaaac tggcttatgt gaccttcgaa agcggtcgtt ccgcgctggt
     7501 tattcagacg ctggcaaatg gcgctgtacg tcaggtggct tcattcccgc gtcacaacgg
     7561 tgcacctgca ttctcgccag acggcagcaa actggcattc gccttgtcga aaaccggtag
     7621 tctgaacctg tacgtaatgg atttggcttc tggtcagatc cgccaggtga ctgatggtcg
     7681 cagtaacaat accgaaccga cctggttccc ggatagccag aacctggcat ttacttctga
     7741 ccaggccggt cgtccgcagg tttataaagt gaatatcaac ggcggtgcgc cacaacgtat
     7801 tacctgggaa ggttcgcaga accaggatgc ggatgtcagc agcgacggta aatttatggt
     7861 aatggtcagc tccaatggtg ggcagcagca cattgccaaa caagatctgg caacgggagg
     7921 cgtacaagtt ctgtcgtcca cgttcctgga tgaaacgcca agtctggcac ctaacggcac
     7981 tatggtaatc tacagctctt ctcaggggat gggatccgtg ctgaatttgg tttctaccga
     8041 tgggcgtttc aaagcgcgtc ttccggcaac tgatggacag gtcaaattcc ctgcctggtc
     8101 gccgtatctg tgataataat taattgaata gtaaaggaat cattgaaatg caactgaaca
     8161 aagtgctgaa agggctgatg attgctctgc ctgttatggc aattgcggca tgttcttcca
     8221 acaagaacgc cagcaatgac ggcagcgaag gcatgctggg tgccggcact ggtatggatg
     8281 cgaacggcgg caacggcaac atgtcttccg aagagcaggc tcgtctgcaa atgcaacagc
     8341 tgcagcagaa caacatcgtt tacttcgatc tggacaagta cgatatccgt tctgacttcg
     8401 ctcaaatgct ggatgcacat gcaaacttcc tgcgtagcaa cccgtcttac aaagtcaccg
     8461 tagaaggtca cgcggacgaa cgtggtactc cggaatacaa catctccctg ggtgaacgtc
     8521 gtgcgaacgc cgttaagatg tacctgcagg gtaaaggcgt ttctgcagac cagatctcca
     8581 tcgtttctta cggtaaagaa aaacctgcag tactgggtca tgacgaagcg gcatactcca
     8641 aaaaccgtcg tgcggtactg gtttactaag agaattgcat gagcagtaac ttcagacatc
     8701 aactattgag tctgtcgtta ctggttggta tagcggcccc ctgggccgct tttgctcagg
     8761 caccaatcag tagtgtcggc tcaggctcgg tcgaagaccg cgtcactcaa cttgagcgta
     8821 tttctaatgc tcacagccag cttttaaccc aactccagca acaactttct gataatcaat
     8881 ccgatattga ttccctgcgt ggtcagattc aggaaaatca gtatcaactg aatcaggtcg
     8941 tggagcggca aaagcagatc ctgttgcaga tcgacagcct cagcagcggt ggtgcagcgg
     9001 cgcaatcaac cagcggcgat caaagcggtg cggcggcatc aacgacgccg acagctgatg
     9061 ctggtactgc gaatgctggc gcgccggtga aaagcggtaa tgcaaacacg gattacaatg
     9121 cagctattgc gctggtgcag gataaatccc gccaggatga cgcaatggtg gcatttcaga
     9181 atttcatcaa aaattaccct gattcaactt acctgccaaa cgccaattat tggctgggtc
     9241 agttaaacta caacaagggt aaaaaagatg atgcggcgta ctattttgct tcggtagtga
     9301 aaaactatcc gaagtcacca aaggctgcag atgcgatgtt taaagtcggc gtcatcatgc
     9361 aggacaaagg tgacaccgca aaagcgaaag ccgtatacca gcaggttatc agtaaatacc
     9421 ctggtactga tggcgctaaa caggcacaaa aacgtctgaa cgcgatgtaa tgcataacac
     9481 acgaccagaa gtcgcattat ttctggtcgt gtcgtgcgaa tcataagcag ttgagtgatc
     9541 tacatcgaaa tttttgttgc gctcaagtct gaaatcagta atatatgccg ccgttgccac
     9601 gggatatcaa acaaaccgaa agcaacgaaa aagtgggtcg ttagctcagt tggtagagca
     9661 gttgactttt aatcaattgg tcgcaggttc gaatcctgca cgacccacca atcgctaagg
     9721 tggaagcggt agtaaaacgt gaaggataac gttgcatgag caacggcccg aagggcgaga
     9781 cgaagtcgag tcatcctgca cgacccacca ctaacatagt tagttgtagt atccagcgta
     9841 gtatcgggtg attagctcag ctgggagagc acctccctta caaggagggg gtcggcggtt
     9901 cgaacccgtc atcacccacc accgggtcgt tagctcagtt ggtagagcag ttgactttta
     9961 atcaattggt cgcaggttcg aatcctgcac gacccaccag ttttaacatc gaagacagat
    10021 gttaagcgtg taggataacg ttgcgtcagc aacggcccgt agggcgagcg aagcgagtca
    10081 tcctgcacga cccaccacta atgacggtgg gttcggtgga agtagtttgt agtatccagc
    10141 gcagtatcgg gtgattagct cagctgggag agcacctccc ttacaaggag ggggtcggcg
    10201 gttcgatccc gtcatcaccc accactcggg tcgttagctc agttggtaga gcagttgact
    10261 tttaatcaat tggtcgcagg ttcgaatcct gcacgaccca ccagttttaa catcaaactc
    10321 agatgttaag cgtgaaggat aacgttgcgc cagcaacggc ccgtagggcg agcgaagcga
    10381 gtcatcctgc acgacccacc aatcttaaag attggccccg agtaaaaatc tttcaggtaa
    10441 cacccgtatg ggtcgttagc tcagttggta gagcagttga cttttaatca attggtcgca
    10501 ggttcgaatc ctgcacgacc caccaattta aaggtggtta ctggtagaga acgtgaagga
    10561 taacgttgcg ttagcaacgg cccgaagggc gagacgaagt cgagtcatcc tgcacgaccc
    10621 accatcctga atgattaagg cagcataatc ccgcaagggg tcgttagctc agttggtaga
    10681 gcagttgact tttaatcaat tggtcgcagg ttcgaatcct gcacgaccca ccaatgtaaa
    10741 aaagcgccct aaaggcgctt ttttgctatc tgcgatactc aaagattcga acctgcagca
    10801 ggtttgagtt gagcgcagcg aaacaacgga gccgctcgcg gcgacggccc gaagggcgag
    10861 cgaagcgagt catcctgcac gacccaccaa tgtaaaaaag cgccctaaag gcgctttttt
    10921 gctattcagg catcctcaat ttcactttgt aaacctgatg acatcgtcag agcttactgt
    10981 gcaagcaact ctatgtcggt ggaattaggc gtaaaatgac gcatcctgca cattaggcgt
    11041 aattcgagtg acttttcccc accattcgac tatcttgttt agcatataaa acaaattaca
    11101 ccgataacag cgaatattac gctaatgtcg gttttaacgt taagcttgta aaacgagatg
    11161 gtaagatgag cgtaatgttt gatccagaca cggcgattta tcctttcccc ccgaagccga
    11221 cgccgttaag cattgatgaa aaagcgtatt accgcgagaa gataaaacgt ctgctaaaag
    11281 aacgtaatgc ggtgatggtt gcccactact ataccgatcc cgaaattcaa caactggcag
    11341 aagaaaccgg tggctgtatt tctgattctc tggaaatggc gcgcttcggt gcaaagcatc
    11401 ccgcttctac tttgttagtc gctggggtga gatttatggg agaaaccgcc aaaattctca
    11461 gtccggaaaa aacaattctg atgccgacac ttcaggctga atgttcactg gatctcggct
    11521 gccctgttga agaatttaac gcattttgcg atgcccatcc cgatcgtact gtcgtcgtct
    11581 acgccaacac ttctgctgcg gtaaaagcgc gcgcagattg ggtggtaact tcaagcattg
    11641 ccgtcgaact tattgatcat cttgatagtt tgggtgaaaa aatcatctgg gcacccgaca
    11701 aacatctggg gcgttacgtg caaaaacaga cgggtggaga cattctatgc tggcagggtg
    11761 cctgtattgt gcatgatgaa tttaagactc aggcgttaac ccgcttgcaa gaagaatacc
    11821 cggatgctgc catactggtg catccagaat caccacaagc tattgtcgat atggcggatg
    11881 cggtcggttc caccagtcaa ctgatcgctg ctgcgaaaac attgccacat cagaggctta
    11941 ttgtggcaac cgatcggggt attttctaca aaatgcagca ggcggtgcca gataaagagt
    12001 tactggaagc accaaccgca ggtgagggtg caacctgccg cagctgcgcg cattgtccgt
    12061 ggatggccat gaatggcctt caggccatcg cagaggcatt agaacaggaa ggaagcaatc
    12121 acgaggttca tgttgatgaa aggctgcgag agagggcgct ggtgccgctc aatcgtatgc
    12181 tggattttgc ggctacacta cgtggataac gaataataag gcgtaacgtt acgctttggg
    12241 ggaaagatgg atttttttag tgtgcagaat atcctggtac atataccaat aggggcaggc
    12301 ggttatgatc tctcatggat cgaagcggta ggcacgatcg ccgggttgct gtgtattggc
    12361 cttgccagtc tggagaagat cagcaactac ttctttggcc tgatcaacgt caccttgttt
    12421 ggcattattt tctttcagat tcagctgtat gccagcctgc tattacaggt gtttttcttt
    12481 gccgcgaata tttacggttg gtatgcgtgg tcgcgacaaa ccagtcagaa cgaggcggag
    12541 ttgaaaattc gctggttgcc attgccgaag gcactcagct ggttggcggt ttgcgttgtt
    12601 tcgattggtc tgatgacggt atttatcaat ccggtgtttg catttttgac ccgcgtggca
    12661 gtcatgatca tgcaagcatt aggattacag gttgtgatgc ctgaactgca accggacgct
    12721 ttcccgttct gggattcatg catgatggtg ttatctatcg tggcaatgat tctgatgacg
    12781 cgtaagtatg tggaaaactg gctgttgtgg gtgattatta acgtgattag cgtcgttatt
    12841 tttgcacttc agggcgttta cgccatgtct ctggagtaca tcatcctgac ctttattgcg
    12901 ctcaacggca gccggatgtg gatcaacagc gcacgtgaaa gaggctcacg cgcgctgtcc
    12961 cattaatggt gatgatgtga atggccagac accccttcat tcaggtggca gtctggccca
    13021 tgacaaggtt gatattccat ctgaatggtg gcgtgctcaa tctgatagtg atccatcagg
    13081 tagtgttgga tctgatccaa caaggcatcg tgatcgtgtg gcgggatcac ctgcacatgc
    13141 aacgtcatca ccggcttctc gcctaccatc catacatgta catggtgcac attgcggact
    13201 tccgggattt cccggcacat acgacgcttc agttcagcga tatccagcga taccggtgca
    13261 ccttcaagta attcattcac gctatctttc aacagtcgcc acgcgctacg cagaaccaga
    13321 agcgacacca gtatcgagag aatggggtca gcaggtgtcc agccagtcca gataataatc
    13381 aacgcggcaa taatagcccc aaccgaaccc agcaggtccc cgagcacatg cagtgccgct
    13441 gctcgtacgt tgaggttttt ctcttcgctg ccgtgatgaa gtaaccagaa agaaagtata
    13501 tttgccagca acccagccac ggcaattgcc atcatcatgc cgccctcgac cggacgcggc
    13561 gtgcggaagc gttctatcgc ctcccagaca atcaaaatgg taattaccac gagggctatg
    13621 gcattcacaa acgccgcgag cgtggtcagt cttagccaac cgaaagtgtg gcgaatggtg
    13681 ggaggacgac gtgaaaattg cacggcgagt agggcgaaaa gcagggcggc agtatcggtc
    13741 aacatatgac ccgcatcggc cagcaatgcc agagaaccag aaagaaaacc accaacgact
    13801 tctaccagca taaacccggc agtcacgccg aaagcataca acaagcgacg agcattatta
    13861 tcttctggca ggtgtgagga cgtgtgtgag tgtgagtgcg ccatgacgag tcatccctta
    13921 attattctca cttaacttta tgacatcata ctgcttttag aagtgaaaaa ttaaaaggga
    13981 gagactccgc tctcccatta ttggctattt tgcagggtta ctgcgtggta ccgtcggttt
    14041 tggtatcgac atcattattg atgccatcac cggtttgtac ctttttattg atatccggac
    14101 agcgaccatc tttgcacatg gtgttcttgt gctcttcatc tttggtcatt ccgtcattgt
    14161 tcattgaaga accatccgaa tgcagcattg tgccgccaga accggtattt accccgttat
    14221 tgtcgacgtt atttggcgcg acattttcac gggcgtcagg ggctacctgg cccgcatcag
    14281 ctgcggcgtt tgcctggccg ttattagttt gcgctccgct atcggcagcc agtgcggcac
    14341 cgctggcaag gcttagagtg gcagtcagaa ataatgtggc cagttttgtc attttcatag
    14401 gatgctcctg ttatggtcgt tatgtcggat aacctcttcc aacagtgcat ttgcaggtga
    14461 atataaggca ttggtttaag atttcagcca ggttatgaaa cgcagcagag aatcttgaaa
    14521 taattaacaa acaaaggagt tacagttaga aattgtagga gagatctcgt ttttcgcgac
    14581 aatctggcgt ttttcttgct aattccagga ttaatccgtt catagtgtaa aaccccgttt
    14641 acacattctg acggaagata tagattggaa gtattgcatt cactaagata agtatggcaa
    14701 cactggaaca gacatgaatt atcagaacga cgatttacgc atcaaagaaa tcaaagagtt
    14761 acttcctcct gtcgcattgc tggaaaaatt ccccgctact gaaaatgccg cgaatacggt
    14821 tgcccatgcc cgaaaagcga tccataagat cctgaaaggt aatgatgatc gcctgttggt
    14881 tgtgattggc ccatgctcaa ttcatgatcc tgtcgcggca aaagagtatg ccactcgctt
    14941 gctggcgctg cgtgaagagc tgaaagatga gctggaaatc gtaatgcgcg tctattttga
    15001 aaagccgcgt accacggtgg gctggaaagg gctgattaac gatccgcata tggataatag
    15061 cttccagatc aacgacggtc tgcgtatagc ccgtaaattg ctgcttgata ttaacgacag
    15121 cggtctgcca gcggcaggtg agtttctcga tatgatcacc ccacaatatc tcgctgacct
    15181 gatgagctgg ggcgcaattg gcgcacgtac caccgaatcg caggtgcacc gcgaactggc
    15241 atcagggctt tcttgtccgg tcggcttcaa aaatggcacc gacggtacga ttaaagtggc
    15301 tatcgatgcc attaatgccg ccggtgcgcc gcactgcttc ctgtccgtaa cgaaatgggg
    15361 gcattcggcg attgtgaata ccagcggtaa cggcgattgc catatcattc tgcgcggcgg
    15421 taaagagcct aactacagcg cgaagcacgt tgctgaagtg aaagaagggc tgaacaaagc
    15481 aggcctgcca gcacaggtga tgatcgattt cagccatgct aactcgtcca aacaattcaa
    15541 aaagcagatg gatgtttgtg ctgacgtttg ccagcagatt gccggtggcg aaaaggccat
    15601 tattggcgtg atggtggaaa gccatctggt ggaaggcaat cagagcctcg agagcgggga
    15661 gccgctggcc tacggtaaga gcatcaccga tgcctgcatc ggctgggaag ataccgatgc
    15721 tctgttacgt caactggcga atgcagtaaa agcgcgtcgc gggtaaggtt taattgtcgg
    15781 atgcgccgtc agagtggcgt atccgatgaa tcaccacagg cctgataagt cgcgcagcgt
    15841 cgcatcaggc aatgtgctcc attgttagca acaaaaaagc cgactcactt gcagtcggct
    15901 ttctcatttt aaacgaatga cgtttacttc gctttaccct ggtttgcaac cgccgctgct
    15961 ttcgctgcga tctcgtcagc attacccaga taatagcgtt tcagcggttt gaaattctcg
    16021 tcgaactcat acaccagcgg cacgccagtc gggatattaa gctcaagaat ctcttcttcg
    16081 ctcatgttat caagatattt caccagcgca cgtaaagagt taccgtgtgc agcgatgatc
    16141 acgcgctcac cgctcttcat acgcggcaga atagtttcat tccagtaagg gatcacgcgg
    16201 tcaatggtca gcgccaggct ttccgtcagc ggcagttctt tctcgctcag tttcgcgtaa
    16261 cgcggatcgt gacccggata acgctcatca tctttagtca gttccggcgg agtcactgca
    16321 aaaccacgac gccactgttt cacctgctcg tcgccatact tttcagcagt ttctgctttg
    16381 ttcagaccct gcaacgcacc gtagtgacgt tcgttcagtt tccaggattt ctcaacgggc
    16441 agccatgcct gatccagttc gtccagcaca ttccacaggg tatggatagc gcgtttcagc
    16501 acagaagtgt aagcaaagtc aaagctgtaa ccttcctctt tcagcagctt acctgctgct
    16561 tttgcttcgc ttacgccttt ctcagacaga tccacgtcgt accaaccggt gaaacggttt
    16621 tctttgttcc actgactttc gccatgacga accagaacca gcttagttac agccatatac
    16681 ttactcctca aatcatcttt taatgataat aattctcatt atattgccgc gacgaagcaa
    16741 cagcaatgct tacgcataac catagcgaaa atagtggcgc agtgtaaggt tgttgtgaat
    16801 attgagttgc aaatatgtcg gtgtttgctg gtgatttgaa caatatgaga taaagccctc
    16861 atgacgaggg cgtaacatta ctcagcaata aactgatatt ccgtcaggct ggaatactct
    16921 tcgccaggac gcaggaagca gtccggttgc ggccattcag ggtggttcgg gctgtccggt
    16981 agaaactcgc tttccagagc cagcccttgc cagtcggcgt aaggttcggt tccccgcgac
    17041 ggtgtgccgc cgaggaagtt gccggagtag aattgcagag ccggagcggt ggtgtagacc
    17101 ttcagctgca atttttcatc tgctgaccag acatgcgccg ccactttctt gccatcgcct
    17161 ttggcctgta acaagaatgc gtgatcgtaa cctttcactt tgcgctgatc gtcgtcggca
    17221 agaaactcac tggcgatgat tttggcgctg cggaaatcaa aagacgttcc ggcgacagat
    17281 ttcaggccgt cgtgcggaat gccgccttca tcaaccggca gatattcgtc cgccagaatc
    17341 tgcaacttgt gattgcgcac gtcagactgc tcgccgtcaa gattgaaata gacgtgatta
    17401 gtcatattca ccgggcaagg tttatcaact gtggcgcgat aagtaatgga gatacggtta
    17461 tcgtcggtca gacgatattg caccgtcgcg ccgagattac ccgggaagcc ctgatcacca
    17521 tcatctgaac tcagggcaaa cagcacctga cgatcgttct ggttcacaat ctgccagcga
    17581 cgtttgtcga acccttccgg cccgccgtgc agctggttaa cgccctgact tggcgaaagc
    17641 gtcacggttt caccgtcaaa ggtataacgg ctattggcga tacggttggc ataacgacca
    17701 atagaggccc ccagaaacgc ggcctgatcc tgatagcatt ccgggctggc acagccgagc
    17761 agcgcctcgc ggacgctgcc atcggaaagc ggaatacggg cggaaagtaa agtcgcaccc
    17821 cagtccatca gcgtgactac catccctgcg ttgttacgca aagttaacag tcggtacggc
    17881 tgaccatcgg gtgccagtgc gggagtttcg ttcagcactg tcctgctcct tgtgatggtt
    17941 tacaaacgta aaaagtctct ttaatacctg tttttgcttc atattgttca gcgacagctt
    18001 gctgtacggc aggcaccagc tcttccggga tcagcgcgac gatacagccg ccaaatccgc
    18061 cgccggtcat gcgtacgcca cctttgtcgc caatcacagc tttgacgatt tctaccagag
    18121 tgtcaatttg cggcacggtg atttcgaaat catcgcgcat agaggcatga gactccgcca
    18181 tcaactcgcc catacgtttc aggtcgcctt gctccagcgc gctggcagct tcaacggtgc
    18241 gggcgttttc agtcagtata tgacgcacgc gttttgccac gatcgggtcc agttcatgcg
    18301 caacagcgtt gaactcttca atggtgacat cacgcagggc tggctgctgg aagaaacgcg
    18361 caccggtttc gcactgttca cgacgggtgt tgtattcgct gccaaccagg gtacgtttga
    18421 agttactgtt gatgatgacg acagccacac ctttgggcat ggaaactgct ttggtcccca
    18481 gtgagcggca atcgatcagc aaggcatgat ctttcttgcc gagcgcggaa attagctgat
    18541 ccatgatccc gcagttacag cctacaaact ggttttctgc ttcctgaccg ttaagcgcga
    18601 tttgtgcgcc gtccagcggc agatgataaa gctgctgcaa tacggttccg accgcgactt
    18661 ccagtgaagc ggaagaactt aacccggcac cctgcggcac attgccgctg atcaccatgt
    18721 ccacgccgcc gaagctgttg ttacgcagtt gcagatgttt caccacgcca cgaacgtagt
    18781 tagcccattg atagttttca tgtgcgacaa tgggcgcatc gagggaaaac tcgtcgagct
    18841 gattttcata atcggctgcc atcacgcgaa ctttacggtc atcgcgtggt gcacaactga
    18901 tcacggtttg ataatcaatc gcgcagggca gaacgaaacc gtcgttgtag tcggtgtgtt
    18961 caccaatcaa attcacgcgg ccaggcgcct gaatggtgtg agtggcaggg tagccaaatg
    19021 cgttggcaaa cagagattgt gttttttctt tcagactcat ttcttacact ccggattcgc
    19081 gaaaatggat atcgctgact gcgcgcaaac gctctgctgc ctgttctgcg gtcaggtctc
    19141 gctgggtctc tgccagcatt tcataaccaa ccataaattt acgtacggtg gcggagcgca
    19201 gcagaggcgg ataaaagtgc gcgtgcagct gccagtgttg attctcttcg ccattaaatg
    19261 gcgcgccgtg ccagcccata gagtagggga aggagcactg gaagaggttg tcataacgac
    19321 tggtcagctt tttcaacgcc agcgccagat cgctgcgctg ggcgtcggtc aaatcggtga
    19381 tccgtaaaac gtgggctttg ggcagcagta gcgtttcgaa cggccaggca gcccagtaag
    19441 gcacgacggc taaccagtgt tcggtttcga caacggtacg gctaccgtct gccagctcgc
    19501 gctgaacata atccaccagc attggtgatt tctgttcggc aaaatattct ttttgcaggc
    19561 ggtcttcgcg ctcagcttcg ttaggcagga agctatttgc ccaaatctga ccgtgcggat
    19621 gcgggttaga gcagcccatc gccgcgcctt tgttttcaaa aacctgcacc catgggtacg
    19681 ttttccccag ttctgcggtt tgctcctgcc aggttttgac gatttccgtc aatgctgcaa
    19741 cgctgagctc tggcagcgtt ttactgtgat ccggtgaaaa gcagatcacc cggctggtgc
    19801 cgcgcgcgct ctggcaacgc atcagcggat cgtgactttc tggcgcatct ggcgtgtcag
    19861 acatcaaagc cgcaaagtca ttagtgaaaa cgtaagtccc ggtgtaatcg gggtttttat
    19921 cgcctgtcac ccgcacatta cctgcgcaga ggaagcaatc tggatcgtgc gcaggtaaca
    19981 cctgtttggc tggcgtttcc tgcgccccct gccaggggcg cttagcgcgg tgcggtgaaa
    20041 ccagaatcca ttgcccggtg agcgggttgt agcggcgatg tggatgatca acgggattaa
    20101 attgcgtcat ggtcgttcct taatcgggat atccctgtgg atggcgtgac tgccagtgcc
    20161 aggtgtcctg cgccatttca tcgagtgtgc gcgttacgcg ccagttcagt tcacggtcgg
    20221 ctttgctggc gtccgcccag taggccggaa ggtcgccctc gcgacgcggt gcaaaatgat
    20281 aattaaccgg tttgccgcag gctttgctga aggcattaac cacgtccagc acgctgttgc
    20341 ctacgccagc gccgaggttg tagatgtgta cgcctggctt gttcgccagt ttttccatcg
    20401 ccacgacgtg accgtccgcc agatccatta cgtggatgta atcgcgtacg ccagtaccat
    20461 cttcggtcgg ataatcgtta ccaaaaatcg ccagcgagtc gcgacggcct acagcaacct
    20521 gggcgatgta tggcatcagg ttattcggaa tgccttgcgg atcttcgccc atatcgcccg
    20581 acggatgcgc gccaaccggg ttgaagtagc gcagcagggc aatgctccag tccggctggg
    20641 ctttttgcag atcggtgagg atctgttcca ccatcagctt gcttttgccg taagggcttt
    20701 gcggtgtgcc ggtcgggaag ctttcaacgt atggaatttt gggctgatcg ccataaacgg
    20761 tggcggagga gctaaaaata aagtttttga cgttagcggc gcgcatggcg ctaatcaggc
    20821 gcagagtgcc gttgacattg ttgtcgtaat attccagcgg tttttgtacc gattcgccca
    20881 cggctttcag cccggcgaag tggatcacgg tgtcgatagc gtgatcgtgc aggatctcgg
    20941 tcatcaacgc ttcgttacga atatcgcctt caacaaacgt tggatgtttg ccgcctaaac
    21001 gctcgataac aggcagtacg ctgcgcttac tgttacagag gttatcaaga atgatgacat
    21061 catgaccgtt ttgcagtaat tgcacacagg tatgacttcc aatgtaaccg ctaccaccgg
    21121 taaccagaac tctcataatt cgctccatta ggcttatggt atgaaataac catagcataa
    21181 caaagatgcg aaaagtgtga catggaataa attagtggaa tcgtttacac aagaatttag
    21241 ccgtttttta tgcgcgatta agtgattata aaacagaggg tttatgaatg attgcgtttt
    21301 ttatctgaaa aaagacgcgg tttcatgcct gcatgcgtcg aaccgttggc cggagagggc
    21361 gctaaggccg cctccggcaa ggtcagcact accgactcaa tatatttttg tcagcacata
    21421 gcgatagagt ccaccgtccg gcacgaactc aagacgatgg gtaatacagg caggcgcatc
    21481 ttcagcgtgg tgcgaaacaa acaacaattg cgtttcacct tcgctaatca gcacatcaac
    21541 aaaacggcgg ataagctggc gattcagcgg atcaagcccc tgtagtggtt catcgagaat
    21601 aagcaacgtc ggatgtttca ccagtgcgcg gacaatcagc gccagacgct gctgtcccca
    21661 ggaaagacta tggaacggag cgtcagccgt gcgtttatca atgccgagaa tatccagcca
    21721 ctgctgcacc agtttttgct ggcgatccga aacggcctga taaatgccaa tcgaatcaaa
    21781 atagccagaa agaatcacat tacgcacggt agtgctgacc cggtaatcca gatgcaaact
    21841 actgctgacg taaccgatat gctttttgat atcccagatg gtttcgccgc tgccgcgacg
    21901 tcgtccgaaa agcgtcaaat cgttgctgta accttgcgga tgatcgccag taaccaggct
    21961 taataacgtc gattttcctg caccatttgg cccgacaatt tgccagtgtt cgcctggatt
    22021 cacctgccag ctaaggttat taagaatggg gcgatcgtta taagaaacca cgccattgtt
    22081 cagcacaatg cgcggttcgt tggcgggtaa ggcgtgacgt gctgaaggtt catccggctc
    22141 cggcagttgc acaccttcaa gctgttcact atgcgccagt tgcgcgacga gtgcttgttg
    22201 gagcagttcc tctttagcgc cagtttccgc taacgtgcaa tccgccagca cgccagcaaa
    22261 ctggacaaac tccgggatct catcgaagcg attgagcacc agtaccagag taataccgga
    22321 ctgatgtaac gaggcgagtc gctcagccag ctgctgacgt gaggcaacat ccaggccatc
    22381 gaacggctca tcaagaatca acaagtcagg ctccgacatc agcgcctgac acagcagggt
    22441 ttttcgcgtc tcgccagtgg aaaggtattt aaagcgtcgg tcgaggaggg cggtaatacc
    22501 gaactgctgc gccagttgca tgcaacgcgg tgcatccttt acttcatcct gaatgatctc
    22561 agccgtagtg cgtccggtgt catcttcgcc agggccgagc atatcggtgt tattccgctg
    22621 ccattcgtcg ctgacgagtt tttgcaattg ctcgaaggag agacgagtga tgtgggaaaa
    22681 ctggctttgc cgttcacctt tcaaaagcgg aagttccccc gccagcgcgc gggccagggc
    22741 cgatttcccg cttccattcg aaccgacaaa cgcccaacta tcacccgcgt ttaacgttag
    22801 ctgaggcaat tgcagcgttt ttgtgtcgct aagacgaaac gtgccttgca aaatttgcaa
    22861 cgatgacatt ttatatccca ctttgtgcag cgattactga cagggatacg tgtttcataa
    22921 caaattgtca acacgcttag cacagcgtgg cgataatcac gctgtcggca ttaaagtagg
    22981 ccgtgacatt ctgtccttgc tgaagagaag tcgcttcatt taccggcact gtggcgcaca
    23041 gtgtttgccc gtcgggtagc gccattaata cttcgcactg ctctgcgccg cgctcaatat
    23101 gactaataat acccggtaat tggttgtcag cgttttgcgc gaccgcctcg tcctgagtaa
    23161 tacctaccca cggcgctttt agcaatatca acacttcttt gccttcatcc agccccagac
    23221 gcgcgccgct ttgtgcggta attgcgactt tcaggcgtgt ttttccgtca gccagtaaga
    23281 catcaacatg ctgttgaacg tcatcatgat cgcgggcggt gatggtaccg aaccactggt
    23341 tacgggcgct ggtttgcagt gaaaaacgtg agatcgcggc cagcaggctg ttcagcggca
    23401 gggcgtcatc gtcacttaac acatcaaagg ctttttgctg gatttgcgcc agtaagtcat
    23461 agagctgaat cagtcgctga ccatagcggg tcagtactgc gccgccgcca cctttaccgc
    23521 ctgttgcgcg ctcgaccaga atatgctcac ttaactgatt catctcgtta atggcatccc
    23581 aggcgctttt atagctaata ccggcatctt tcgctccctg gctaatggaa ccggaaagcg
    23641 caatgtgttt tagtagcgaa atgcggcgcg ggtcggcgaa taatttttgt tggagcttaa
    23701 gggtgagaag gatttcggcc tgcataacaa tgtcctggca aaagtcttat tgtgacggaa
    23761 aacgagcgcc acgcaaagct gaccgcacaa aaggggagtg cttttctgtg cttagcggtt
    23821 agaatagtct catgactata tctggagttg accatgttag agttattaaa aagtctggta
    23881 ttcgccgtaa tcatggtacc tgtcgtgatg gccatcatcc tgggtctgat ttacggtctt
    23941 ggtgaagtat tcaacatctt ttctggtgtt ggtaaaaaag accagcccgg acaaaatcat
    24001 tgattccctg aatgcccgct tagtcgggca ttttcttttt ctcaacttcc tgcttttcct
    24061 gccgatattt tttcttatct acctcacaaa ggttagcaat aactgctggg aaaattccga
    24121 gttagtcgtt atattgtcgc ctacataacg ttacattaag gggttaccaa tggctcgtaa
    24181 atggttgaac ttgtttgccg gggcggcact ctctttcgct gttgctggca atgcactggc
    24241 agatgaaggg aaaatcacgg tgttcgccgc cgcatcactg actaacgcaa tgcaggacat
    24301 tgctacgcag tttaaaaaag agaaaggcgt ggatgtggtt tcttctttcg cttcgtcatc
    24361 tactctcgcc cgtcagattg aagcgggtgc gcctgcggat ctgtttattt ctgccgatca
    24421 gaaatggatg gattatgcgg ttgataaaaa agcgatcgat acagctacgc gtcagacact
    24481 gctcggcaat agcctggtcg ttgtagcacc gaaagccagc gtgcagaaag atttcaccat
    24541 cgacagcaaa accaactgga cttcactgct gaatggcggt cgcctggcgg ttggcgatcc
    24601 ggaacatgtt cccgctggca tttatgcaaa agaagcactg caaaaactgg gcgcatggga
    24661 tacgctctct ccgaaactgg ccccagcgga agatgttcgt ggggcgctgg cgctggtcga
    24721 acgtaacgaa gcgcctctgg gcattgtcta cggttctgac gcagttgcca gcaaaggggt
    24781 aaaagtggtt gccaccttcc cggaagattc acataaaaaa gtggaatatc cggttgctgt
    24841 tgtggaaggg cataacaatg cgacagtgaa agcattttat gattatctga agggaccgca
    24901 ggcagcggaa atctttaaac gttacggatt tacaatcaag taatgatact gaccgatcca
    24961 gaatggcagg cagttttatt aagcctgaaa gtttcttccc tggctgtgct gtttagcctg
    25021 ccgtttggga tcttttttgc ctggttactg gtgcgttgca cgtttccggg caaagctctg
    25081 ctcgacagcg tactgcatct accgctggtg ttaccgcccg tggtcgtcgg ttacttatta
    25141 ttagtttcga tgggacggcg cggatttatc ggtgaacgtc tgtatgactg gtttggtatt
    25201 accttcgcct ttagctggcg cggcgcggtt ctcgctgccg ccgtcatgtc gtttccgctg
    25261 atggtgcggg caattcgtct ggcgctggaa ggggttgatg tcaaactgga acaggccgca
    25321 agaacactgg gggccgggcg ctggcgcgtt ttctttacta tcacgttacc gctgacctta
    25381 ccgggaatta ttgttggtac ggtactggct tttgctcgtt ctctcggtga gtttggtgca
    25441 accatcacct ttgtgtcgaa cattcctggt gaaacgcgaa ccattccttc tgccatgtat
    25501 accctgatcc agacccccgg cggggaaagt ggagcggcga gactgtgcat tatttctatt
    25561 gcgctggcga tgatctccct gttgatttca gaatggctgg ccagaatcag ccgtgaacgg
    25621 gcggggcgct aatcatgctg gaactgaatt tttcccagac gttgggcaac cattgcctga
    25681 ctattaatga aacgctgccc gccaatggca tcactgctat ctttggcgtc tccggtgccg
    25741 gaaaaacttc gctgattaac gccatcagtg gactgacgcg cccgcaaaaa gggcggattg
    25801 tcctcaatgg gcgggtacta aatgatgccg aaaaaggtat ctgcctgacg ccggaaaagc
    25861 gtcgcgttgg ctatgttttt caggatgcgc ggctgttccc gcattacaaa gtgcgtggca
    25921 atctgcgcta cggcatgtcg aaaagtatgg tcgatcagtt cgataagctg gtggcgcttt
    25981 taggcattga accgttgctt gaccgtttac caggcagcct gtccggaggc gaaaaacagc
    26041 gcgtggcgat tggtcgggct ttgctgacag caccggaatt gctgttgctg gatgaaccgc
    26101 tggcgtcact ggatattccg cgtaaacgcg aactgttgcc ttatctgcaa cggctgacac
    26161 gggaaatcaa cattccgatg ttgtatgtca gccattcgct ggatgagatc ctccatctgg
    26221 cagacagagt gatggtactg gaaaacggtc aggtgaaagc ctttggcgcg ctggaggaag
    26281 tgtggggcag tagcgtgatg aatccgtggc tgccgaaaga gcaacaaagt agcattctga
    26341 aagtgacggt gcttgagcat catccgcatt acgcgatgac cgcgctggcg ctgggcgatc
    26401 agcatttgtg ggtcaataag ctggacgaac cgctgcaagc tgcgctacgt atccgcattc
    26461 aggcttccga tgtttctctg gttttacaac cgccgcagca aaccagcatt cgtaacgtat
    26521 tgcgggcaaa agttgttaat agttatgacg acaacggcca ggtggaagtg gaactggaag
    26581 tcggcggtaa aacgctgtgg gcgcgtatca gcccgtgggc cagggatgaa ctggcgatca
    26641 aacctggcct gtggctgtac gcgcaaatta aaagtgtgtc gataaccgcc tgattaaatc
    26701 aggtggctat aaatgaactg ggcaatgctg tcggtggtgt tatcaccaat cacaatgttg
    26761 gcgcgcgctt ttaccgcgtc atcggcgttg cccatcgcca cgcctgtacc agcggcttcc
    26821 agcatactga tatcattaaa gctatcgccg aatgccacga cgttttccat cgaccaacct
    26881 tgcgcctcaa cccatttcgt caaacgttta cctttgctgt tgccgccgcg tgcaatatca
    26941 acctgatcgt gccaggacca ttcacactcc agtcccagtt catgttcgac atgcttacca
    27001 aaatgctgca attgcggcag gtcatcgtgc gtcagggcga acttccatac ggcgttaact
    27061 tgttgcgccg tttcagccag agaagcgact tgtgtgaaag tcggacgctg ttccggcggc
    27121 agggtttgcg cccagttaga tgtgcgaatg acatgcccgg tcgggtgctc atagaccatt
    27181 gcatcatcga catacatcag accgtgaatg tggtgttcat tcagcatctc aatgagttgc
    27241 agggctttaa taacgggcat tgggtccgct tccagcacgg tttttgcatg ataatcatac
    27301 aaataggtgc cattacagca aatagcaggt gtatccagcg ccagcgcctg ataaaaagga
    27361 tgaatagcga cgtgatggcg acctgtgacg atgattaatt gatagcctgc ttcgcgagcg
    27421 cgggccaggg cttctatcga tgaaggaagc agggtctttt tcggggtcaa taaggtgccg
    27481 tctaagtcga gagcaatcac gcgtgtggtc atggcgtatt ccagattaag gttaagaatt
    27541 ttcgtctgcg cgaatggtac accgatacca ctatcggaca aaattctgcg ttttaattca
    27601 gcattcaccg ccaaaagcga ctaattttag ctgttacagt cagttgctaa atgcaaagga
    27661 gcattcatga agcaaacagt ttatatcgcc agccctgaga gccagcaaat tcacgtctgg
    27721 aatctgaatc atgaaggcgc actgacgctg acacaggttg tcgatgtgcc ggggcaggtg
    27781 cagccgatgg tggtcagccc ggacaaacgt tatctctatg ttggtgttcg ccctgagttt
    27841 cgcgtcctgg cgtatcgtat cgccccggac gatggcgcac tgacctttgc cgcagagtct
    27901 gcgctgccgg gtagtccgac gcatatttcc accgatcacc aggggcagtt tgtctttgta
    27961 ggttcttaca atgcgggtaa cgtgagcgta acgcgtctgg aagatggcct gccagtgggc
    28021 gtcgtcgatg tggtcgaggg gctggacggt tgccattccg ccaatatctc accggacaac
    28081 cgtacgctgt gggttccggc attaaagcag gatcgcattt gcctgtttac ggtcagcgat
    28141 gatggtcatc tcgtggcgca ggaccctgcg gaagtgacca ccgttgaagg ggccggcccg
    28201 cgtcatatgg tattccatcc aaacgaacaa tatgcgtatt gcgtcaatga gttaaacagc
    28261 tcagtggatg tctgggaact gaaagatccg cacggtaata tcgaatgtgt ccagacgctg
    28321 gatatgatgc cggaaaactt ctccgacacc cgttgggcgg ctgatattca tatcaccccg
    28381 gatggtcgcc atttatacgc ctgcgaccgt accgccagcc tgattaccgt tttcagcgtt
    28441 tcggaagatg gcagcgtgtt gagtaaagaa ggcttccagc caacggaaac ccagccgcgc
    28501 ggcttcaatg ttgatcacag cggcaagtat ctgattgccg ccgggcaaaa atctcaccac
    28561 atctcggtat acgaaattgt tggcgagcag gggctactgc atgaaaaagg ccgctatgcg
    28621 gtcgggcagg gaccaatgtg ggtggtggtt aacgcacact aaccgctgat ttacccggcg
    28681 cagtctctcc tgcgccggtg tattaaccta tctcctgtaa cgcgtgtctc tggcgttcga
    28741 cgatattggt ccacaaattg tctttatcgt cagtccataa attaatcagc aaggcaaaaa
    28801 agcgttctgc tgctggagaa agtacggcat ctttacggcg aattattccc aatgttcgac
    28861 gtataacggg ttccaccaat gggataccaa taatcgaaga atagggcgca tgaggcattg
    28921 ccaggccagg aagcgccgaa atccccagtc ccgcctccac cagtcctaat gacgtcgaaa
    28981 gatgacgcac ttcgtaaaac cagtccagct tccagggctt gtcggccagc tgttgttcta
    29041 tcaacagtcg gttgccgctg gaggagcgta cgccaatcat tttgtaaccc actaactcct
    29101 gccattctac aagctgcttt ttggccaatg gatggtcacg ccgacaggcc agcacgaacg
    29161 gctcgttgac cagtggggta aaatcaatgg atgaatttgt gacgttgttc atgtttatgc
    29221 caaagtctga ttcgttacac agcaccgatt ccatgcaatt attcgtgcct tgttccagaa
    29281 tccgcacttt aatattggga tacagctcat taaatttacc gattgccagc ggtaaaaaat
    29341 aaaatactgc ggtcggaata cacgctaacg tcaccatacc acgatgataa gcattcatat
    29401 cacgaatatt aaaaagcgtt tcatcgaatt tctttattaa ttcccgcgcc tccgggagca
    29461 acctttttcc tgcttttgtt aacgtaacct tgcgagttgt acgctcaaat agttgaatat
    29521 gtaaatcttc ctccatcttt tttattcttc gcgttaatgc aggttgcgta atattgagta
    29581 atttagcggc attgttaaac gaactggact ctgccagtat gacaaatgcc ttcatacttg
    29641 ataattcatg cttcattatt actccggaaa atggaagcga cgattttggg tggctggccg
    29701 ttaaaaattt taactgcatt tagccaactt aaattaatga aaaaatgtta ttaatcgttg
    29761 agctaaagtc attagagatg ctttgccctt aatgtaacca tatcgcaata agttatgttt
    29821 ttaaattgag ggcattatta tgaaaaaata ccctgcgtga tgatgcgagg tggaacctcg
    29881 aggggcgcgt tcctgttagc ggaacattta cccgaagatc aaacgcagcg cgataaaata
    29941 ttgatggcaa ttatgggttc cggtaacgat ctggaaattg acggtattgg cggcggtaat
    30001 ccactgacca gtaaagtcgc cattattagc cgttccagcg atccgcgtgc tgatgtcgat
    30061 tatctgtttg cgcaggtaat cgttcatgag caacgtgtcg ataccacgcc taactgcggc
    30121 aatatgctgt ctggtgttgg ggcattcgcc attgaaaatg gtttgattgc agcgacttcg
    30181 ccagttactc gcgtacgtat ccgcaacgtc aatacgggta cgttcatcga agctgatgtg
    30241 caaacgccaa atggtgttgt cgagtacgag ggtagcgcca gaattgacgg cgtaccgggt
    30301 actgccgcac cggttgcgct cactttcctg aatgccgctg gaaccaaaac cggaaaagtt
    30361 ttcccgactg ataatcagat tgattatttt gacgatgtcc cggtgacctg tatcgatatg
    30421 gcgatgccag tcgtcattat tccggctgaa tatctgggaa aaacaggtta tgaattaccg
    30481 gcggaactgg atgccgacaa agcattatta gcccgcattg aatctatccg tctacaagcg
    30541 ggtaaagcaa tgggcttagg tgatgtcagt aatatggtta tccctaaacc tgtgcttatt
    30601 tctccagcgc agaaaggcgg ggcaattaat gtgcgttatt ttatgccgca ttcttgccat
    30661 cgcgcgctgg cgataaccgg tgctattgct atttccagta gttgtgcatt ggaaggcacc
    30721 gtcacccgac aaatcgtccc ttctgtagga tacggcaata tcaatattga acaccccagt
    30781 ggtgcgctcg acgttcattt aagtaatgaa ggtcaggatg ccacgacgtt acgcgcatct
    30841 gttattcgga cgaccagaaa aatattttcc ggtgaagttt atcttccctg aaaaaattcg
    30901 ttgtcaggat aaggacaatc aataaaggac ttctgtatga gtcatacaga aagaacagga
    30961 ttttaaatga ataagaaatc gttatggaag ctaattctga tattagcgat cccatgtatt
    31021 attggtttta tgccagctcc ggcaggatta agcgaactgg cgtgggtgct ttttggtatt
    31081 tacctggcgg ccattgtggg gctggttatc aagcctttcc cggaacctgt cgtactgtta
    31141 attgccgttg ctgcctcaat ggtggtggtc ggtaacttat ccgacggtgc gtttaaaacc
    31201 accgccgtat taagcggtta ctcttcaggt accacctggc tggtgttctc ggcgtttacc
    31261 ttaagcgccg catttgtgac caccggttta ggtaaacgta ttgcctatct gctgattggt
    31321 aaaatcggta acaccacgct gggtctgggt tacgttacgg tattcctcga tctggtactg
    31381 gctccggcaa caccgtctaa caccgcgcgt gcgggcggca ttgtgttacc gatcatcaac
    31441 agcgtggcgg tggctttggg gtccgaaccg gaaaaaagtc cgcgtcgtgt cggacattac
    31501 ctgatgatgt ccatttacat ggtcaccaaa accaccagct atatgttctt taccgcaatg
    31561 gcggggaaca ttctggcgct gaaaatgatc aacgacattc tgcacctgca aattagctgg
    31621 ggtggatggg cgctggcagc cggattgccg ggcatcatta tgctgctggt caccccgctg
    31681 gtgatttaca ccatgtatcc accagaaatt aagaaggtgg ataacaaaac catcgctaaa
    31741 gcgggccttg ccgaactagg accgatgaaa atccgcgaaa aaatgctgct cggtgtcttt
    31801 gtgctggcgc tgctgggctg gattttcagt aagtctctgg gggttgatga atccaccgtg
    31861 gcaatcgttg ttatggcaac catgctgctg ctgggtatcg ttacctggga agacgtggtt
    31921 aaaaataaag gcggctggaa taccttaatc tggtacggcg gtattatcgg cttaagctcc
    31981 ttattatcga aagttaaatt cttcgaatgg ttagctgaag tctttaaaaa taacctggca
    32041 tttgatggtc acggtaacgt tgctttcttc gttattattt tcctcagcat tatcgtgcgt
    32101 tatttcttcg cttccggtag tgcctatatc gttgctatgt taccggtatt tgccatgctg
    32161 gcgaacgtct ccggcgcacc gttaatgtta accgcgctgg cactgttgtt ctccaactcc
    32221 tatggcggca tggttactca ctatggcggc gcggcaggtc cggtcatctt tggcgtgggt
    32281 tataacgata ttaaatcctg gtggttggtc ggtgcggtac tgacgatatt aaccttcctg
    32341 gtgcatatca ccctcggcgt gtggtggtgg aatatgctga tcggctggaa catgctgtaa
    32401 atattctcgt catacttcaa gttgcatgtg ctgcgtctgc gttcgctcac cccagtcact
    32461 tacttatgta agctcctggg gattcactcg cttgtcgcct tcctgcaact cgaattattt
    32521 agagtatatc catttattat ctttctgcgc acttcacggt gcgcagatat ctggagcatt
    32581 tgatgatcaa gttatctgaa aaaggcgtgt ttctcgccag taataacgaa ataattgccg
    32641 aagaacattt caccggcgaa attaaaaaag aagaagccaa aaaaggcact attgcctggt
    32701 ctattctctc ttcgcataat acgtccggaa atatggataa acttaaaatt aagtttgatt
    32761 cattagcctc tcacgatatt acctttgttg gtattgtaca gaccgctaaa gcgtccggta
    32821 tggaacgttt cccgctgccg tatgtgctga ccaactgcca taactcactc tgcgccgtcg
    32881 gcggcactat taacggtgat gaccatgttt ttggtttatc ggcggcccag cgttatggcg
    32941 gtatttttgt gcctccgcat attgcggtca tccatcaata tatgcgtgag atgatggcag
    33001 gcggcggcaa aatgatcctc gggtcagaca gccacacccg ttacggtgca ttagggacaa
    33061 tggcagtcgg tgagggcggc ggtgagttgg taaaacagct gcttaatgac acctgggata
    33121 tcgactatcc gggcgtggtt gcggtgcatc tgaccggaaa acctgcgccg tatgtggggc
    33181 cacaggatgt ggcgctggct atcattggcg cggtgttcaa aaacggttac gtcaaaaaca
    33241 aagtcatgga gttcgttgga ccgggcgtta gcgcgctctc taccgatttc cgtaacagcg
    33301 ttgacgtgat gaccactgaa acgacctgtt taagttctgt ctggcaaacc gatgaagaag
    33361 tccataactg gctggcgctg cacggtcgcg gccaggatta ctgccagctt aaccctcaac
    33421 cgatggcgta ctacgatggc tgcatcagcg ttgatttaag cgccatcaaa ccaatgattg
    33481 cgctgccgtt ccacccgagc aacgtgtatg aaatcgacac actgaaccag aacctgaccg
    33541 acattctgcg tgagattgaa attgagtccg aacgcgtggc gcacggtaaa gccaaactct
    33601 cgctgctgga taaagtggaa aatggtcgcc tgaaagtgca gcaggggatt atcgcgggct
    33661 gttctggcgg taactacgaa aacgtcatcg cggcggcgaa tgcactgcgc ggtcaatcct
    33721 gtggcaatga caccttctcg ctggcagttt acccgtcatc acagccggtg tttatggatc
    33781 tcgccaaaaa aggtgtggta gcagatttga ttggcgcagg cgcaatcatc agaaccgcgt
    33841 tctgcggccc atgctttggc gcgggcgata cgccaatcaa caacggtttg agtattcgcc
    33901 acaccacgcg taacttcccg aaccgcgaag gctctaagcc agctaatggg cagatgtcag
    33961 cggtggcgtt gatggacgct cgttctatcg ctgcgactgc ggcaaacggt ggctatttaa
    34021 cctctgccag cgaacttgat tgctgggaca acgtgccgga gtacgccttc gatgtaacgc
    34081 cgtataaaaa ccgtgtttat cagggctttg tgaaaggggc aactcagcaa ccgctgattt
    34141 acgggccgaa cattaaagac tggccggaat tgggtgcgct gactgacaat atcgtcctga
    34201 aagtgtgctc gaagatcctc gacgaagtga ccaccaccga cgaactgatt ccttccggtg
    34261 aaacctcttc ttatcgttca aatccgattg gtctggcgga gtttaccctg tctcgccgcg
    34321 atcccggtta tgttagcaga agtaaagcga ctgctgagct ggaaaatcag cgtctggcgg
    34381 ggaatgtcag cgagctgaca gaggtgtttg cgcgcattaa gcagattgct ggtcaggagc
    34441 atattgatcc gctgcaaact gaaattggca gcatggtcta tgcggtgaaa ccaggcgatg
    34501 gttctgcgcg tgaacaggcg gcgagctgcc agcgtgtgat tggcggtctg gcgaatattg
    34561 ccgaggagta cgcgactaaa cgctatcgtt ctaacgtcat caactggggg atgttaccgc
    34621 tgcaaatggc ggaagtacca acctttgaag tgggggatta catttacatc cctggcatta
    34681 aagcggcgct ggataatccg ggtacgacgt ttaaaggtta tgtgatccat gaagatgcgc
    34741 cggtaacgga aattacgctc tatatggaaa gtctgactgc tgaagagcgc gagattatca
    34801 aggcgggtag tttgattaac ttcaataaaa accgtcagat gtaaaaagcg ccatgtgaat
    34861 gtaggtcgca ttcggcactt attgtcggat gcgatgcttg cgcatcttat ccgacctacg
    34921 aatcgcatcg aatctgtagg ccagataagg cattttcgca gcatccggca cttattgtcg
    34981 gatgcgatgc ttgcgcatct tatccgacct acaaatcgca tcgaaccgta ggccggataa
    35041 agcgtttacg ccgcatccgg caaatagtta attgctctta cttcttcgcc tctgcaacca
    35101 ctttactacc cacgccgcgg ttattgtatt cccacatgcg gttgtagtta gtgtcattca
    35161 gattgcgctg tatttcgtcg ttatcatcta cgctgccggt attacccgca aacggacgat
    35221 tagagatcac cgcatcggcc cacggtttag ccgtgttaaa accttcgttg atggcgctat
    35281 cacggatcac cacctgaccg ttggtattgg catcaacatc cagcgagcgg cccagttgcg
    35341 ccacaccatc accgaaagca ttgaaacggc tgtttacggc gaggaaaccg tagtaaatgt
    35401 tggacagcgt agccggtgca aacacatacg cttcttgctg agtacgtgag ttcaccacgc
    35461 ggaattcggt gttatcgaac accactgcgc cgcgaccaga aacgatatcc acatcccctt
    35521 caatgtagct gttggtcacc agcgtacgcg gctgacgatt cgtttccaga cggttctgca
    35581 caccgctgtt ggtgacaaag aaggtgttct gacgaccgag aatgttaacg ttgttaatct
    35641 gtacctggtc accatcagta cgcagtgcca ccgccggatg gttacctgca tctacgctat
    35701 cgcccagcgt gttttcgatg gtcagatttt gcagttgcag gccattgttt tgtgaccaga
    35761 agaccgcaga gcagagaaca ccgatactgt cgctgcgttt gctctggcag ctatcgtaca
    35821 tataccacgc tggtttacct ggcatatatt tgccgcgcgg gttgacgtcg tgacgccagt
    35881 cggcagggct catgccacca tcaagggaaa gcccaatctt cacatcaatc ggtttttcac
    35941 ctgtaccgta cagagtaatt ccacccggag cggcagggac atataccgtt ccctgatact
    36001 caccaggcat cacggcaata tactggcgct tgttggtacg cttgataatt gccgcatcta
    36061 ccgccgcctg aatcgtggta tgcgttacac cttgagtgcc cgccgggccg acaacaaagt
    36121 caggttgcgc aggcagggta atcggggaag gattccacgc tgcagcacct ggtgtcaggg
    36181 atgcaaaata gtgttgagca tcgaaattct gcgcttcttt tgccgacaga atcgggcgag
    36241 aagaggtacc aggcgcggtt tgatcagaag gacgttgatc gggcggggtt gagctacagg
    36301 cggtcagcgt cacgccaaaa gccaatgcca gcgccagacg ggaaactgaa aatgtgttca
    36361 caggttgctc cgggctatga aatagaaaaa tgaatccgtt gaagcctgct tttttatact
    36421 aacttgagcg aaacgggaag gtaaaaagac aaaaagttgt ttttaatacc tttaagtgat
    36481 accagatggc attgcgccat ctggcagagt gattaactaa acatcgcagt aatcgaggcg
    36541 cttgccagag agtggaaatg aacgttaaac ccgaccatcg cgccgctggc accttcatcg
    36601 acatcaatac gttctatatc cagcgcgtga acggtaaaaa tgtagcgatg agtttcgcct
    36661 ttcggcggtg ctgcgccatc gtacccggtt ttaccaaagt cggtacgcgt ctgcaaaacg
    36721 ccgtctggca ttgctaccag accagagcca aacccttgcg gtaatacgcg ggtatcagcg
    36781 ggtaagttaa caactaccca gtgccaccag ccggagccgg ttggcgcatc cgggtcgtag
    36841 caggtgacaa caaaactttt cgttcccgca ggaacatcat cccacgccag atgcggtgaa
    36901 atattatcgc catcgtaacc catgccgtta aagacatgac gatgcggcaa tttatcgcca
    36961 tcgcgcagat cgttactgat gagtttcatg aaccctcctt tcttgtttgc agaaagtgta
    37021 gccagaaacc ctcacgcgga cttctcgtta ttggcaaaaa aatgtttcat cctgtaccgc
    37081 gcggttaacc gctgcggtca gacgctgcaa ctgttgcggg agaataatat agggcggcat
    37141 caggtaaatc agtttgccaa aaggccggat ccagacaccc tgttcgacaa agaatttttg
    37201 cagcgccgcc atattcaccg gatgagtggt ttcgaccacg ccaatggccc ccagtacgcg
    37261 cacatcggca accatttcgg catcacgggc gggggcaagt tgctcgcgca gctgtacttc
    37321 aatatccgcc acctgttgct gccagtcgcc agattcgaga atcgccaggc tggcgtttgc
    37381 tgccgcgcag gccagcggat tgcccataaa agttggccca tgcataaagc aaccggcttc
    37441 accgttactg atggtttctg caacctcgcg cgtggtgagt gtggcggaaa gggtcattgt
    37501 gccgccggtt aaggctttac cgaggcacaa aatgtccggc gcgatttctg catgttcaca
    37561 ggcaaacagt ttcccggtac gaccaaatcc agtggcgatc tcgtcggcaa tcagcaagat
    37621 accttcgcga tcgcatattt tgcggattcg ttttaaccat tccggatggt acatgcgcat
    37681 cccgcctgcg ccctggacaa tcggctcaat gatcaccgcc gcgatttcat gacgatgcgc
    37741 cgccatcagg cgggcaaagc ccaccatatc gcgctcatcc cattcgccat ccatgcggct
    37801 ttgcggggcg ggagcaaaca ggttttctgg caggtagcct ttccacagac tgtgcattga
    37861 gttatccgga tcgcacaccg acatcgcgcc aaaggtatcg ccatgataac cattgcggaa
    37921 ggtcagaaaa cgctggcgcg cttcgccttt ggcttgccag tactgcaacg ccattttcat
    37981 cgccacttcc accgctacgg aaccggagtc cgcgagaaaa acgcactcca gcggttgcgg
    38041 cgtcatcgcc accagtttgc ggcacagctc aatggctggc gcatgggtga taccgccaaa
    38101 catcacatgc gacatggcat caatttgcga cttcatcgcc gcattaagct gcgggtgatt
    38161 gtagccgtgg atcgccgccc accaggacga cataccgtca accaggcgtc tgccgtcaga
    38221 caaaatcagc tcgcaacctt cggcgctcac caccggataa accggcagag gggaggtcat
    38281 ggatgtgtat gggtgccaga tatggcgttg gtcaaaggca agatcgtccg ttgtcataat
    38341 cgacttgtaa accaaattga aaagatttag gtttacaagt ctacaccgaa ttaacaacaa
    38401 aaaacacgtt ttggagaagc cccatggctc accgcccacg ctggacattg tcgcaagtca
    38461 cagaattatt tgaaaaaccg ttgctggatc tgctgtttga agcgcagcag gtgcatcgcc
    38521 agcatttcga tcctcgtcag gtgcaggtca gcacgttgct gtcgattaag accggagctt
    38581 gtccggaaga ttgcaaatac tgcccgcaaa gctcgcgcta caaaaccggg ctggaagccg
    38641 agcggttgat ggaagttgaa caggtgctgg agtcggcgcg caaagcgaaa gcggcaggat
    38701 cgacgcgctt ctgtatgggc gcggcgtgga agaatcccca cgaacgcgat atgccgtacc
    38761 tggaacaaat ggtgcagggg gtaaaagcga tggggctgga ggcgtgtatg acgctgggca
    38821 cgttgagtga atctcaggcg cagcgcctcg cgaacgccgg gctggattac tacaaccaca
    38881 acctggacac ctcgccggag ttttacggca atatcatcac cacacgcact tatcaggaac
    38941 gcctcgatac gctggaaaaa gtgcgcgatg ccgggatcaa agtctgttct ggcggcattg
    39001 tgggcttagg cgaaacggta aaagatcgcg ccggattatt gctgcaactg gcaaacctgc
    39061 cgacgccgcc ggaaagcgtg ccaatcaaca tgctggtgaa ggtgaaaggc acgccgcttg
    39121 ccgataacga tgatgtcgat gcctttgatt ttattcgcac cattgcggtc gcgcggatca
    39181 tgatgccaac ctcttacgtg cgcctttctg ccggacgcga gcagatgaac gaacagactc
    39241 aggcgatgtg ctttatggca ggcgcaaact cgattttcta cggttgcaaa ctgctgacca
    39301 cgccgaatcc ggaagaagat aaagacctgc aactgttccg caaactgggg ctaaatccgc
    39361 agcaaactgc cgtgctggca ggggataacg aacaacagca acgtcttgaa caggcgctga
    39421 tgaccccgga caccgacgaa tattacaacg cggcagcatt atgagctggc aggagaaaat
    39481 caacgcggcg ctcgatgcgc ggcgtgctgc cgatgccctg cgtcgccgtt atccggtggc
    39541 gcaaggagcc ggacgctggc tggtggcgga tgatcgccag tatctgaact tttccagtaa
    39601 cgattattta ggtttaagcc atcatccgca aattatccgt gcctggcagc agggggcgga
    39661 gcaatttggc atcggtagcg gcggctccgg tcacgtcagc ggttatagcg tggtgcatca
    39721 ggcactggaa gaagagctgg ccgagtggct tggctattcg cgggcactgc tgtttatctc
    39781 tggtttcgcc gctaatcagg cagttattgc cgcgatgatg gcgaaagagg accgtattgc
    39841 tgccgaccgg cttagccatg cctcattgct ggaagctgcc agtttaagcc cgtcgcagct
    39901 tcgccgtttt gctcataacg atgtcactca tttggcgcga ttgcttgctt ccccctgtcc
    39961 ggggcagcaa atggtggtga cagaaggcgt gttcagcatg gacggcgata gtgcgccact
    40021 ggcggaaatc cagcaggtaa cgcaacagca caatggctgg ttgatggtcg atgatgccca
    40081 cggcacgggc gttatcgggg agcaggggcg tggcagctgc tggctgcaaa aggtaaaacc
    40141 agaattgctg gtagtgactt ttggcaaagg atttggcgtc agcggggcag cggtgctttg
    40201 ctccagtacg gtggcggatt atctgctgca attcgcccgc caccttatct acagcaccag
    40261 tatgccgccc gctcaggcgc aggcattacg tgcgtcgctg gcggtcattc gcagtgatga
    40321 gggtgatgca cggcgcgaaa aactggcggc actcattacg cgttttcgtg ccggagtaca
    40381 ggatttgccg tttacgcttg ctgattcatg cagcgccatc cagccattga ttgtcggtga
    40441 taacagccgt gcgttacaac tggcagaaaa actgcgccag caaggctgct gggtcacggc
    40501 gattcgcccg ccaaccgtac ccgctggtac tgcgcgactg cgcttaacgc taaccgctgc
    40561 gcatgaaatg caggatatcg accgtctgct ggaggtgctg catggcaacg gttaataaac
    40621 aagccattgc agcggcattt ggtcgggcag ccgcacacta tgagcaacat gcagatctac
    40681 agcgccagag tgctgacgcc ttactggcaa tgcttccaca gcgtaaatac acccacgtac
    40741 tggacgcggg ttgtggacct ggctggatga gccgccactg gcgggaacgt cacgcgcagg
    40801 tgacggcctt agatctctcg ccgccaatgc ttgttcaggc acgccagaag gatgccgcag
    40861 accattatct ggcgggagat atcgaatccc tgccgttagc gactgcgacg ttcgatcttg
    40921 catggagcaa tctcgcagtg cagtggtgcg gtaatttatc cacggcactc cgcgagctgt
    40981 atcgggtggt gcgccccaaa ggcgtggtcg cgtttaccac gctggtgcag ggatcgttac
    41041 ccgaactgca tcaggcgtgg caggcggtgg acgagcgtcc gcatgctaat cgctttttac
    41101 cgccagatga aatcgaacag tcgctgaacg gcgtgcatta tcaacatcat attcagccca
    41161 tcacgctgtg gtttgatgat gcgctcagtg ccatgcgttc gctgaaaggc atcggtgcca
    41221 cgcatcttca tgaagggcgc gacccgcgaa tattaacgcg ttcgcagttg cagcgattgc
    41281 aactggcctg gccgcaacag caggggcgat atcctctgac gtatcatctt tttttgggag
    41341 tgattgctcg tgagtaaacg ttattttgtc accggaacgg ataccgaagt ggggaaaact
    41401 gtcgccagtt gtgcactttt acaagccgca aaggcagcag gctaccggac ggcaggttat
    41461 aaaccggtcg cctctggcag cgaaaagacc ccggaaggtt tacacaatag cgacgcgctg
    41521 gcgttacagc gcaacagcag cctgcagctg gattacgcaa cagtaaatcc ttacaccttc
    41581 gcagaaccca cttcgccgca catcatcagc gcgcaagagg gcagaccgat agaatcattg
    41641 gtaatgagcg ccggattacg cgcgcttgaa caacaggctg actgggtgtt agtggaaggt
    41701 gctggcggct ggtttacgcc gctttctgac actttcactt ttgcagattg ggtaacacag
    41761 gaacaactgc cggtgatact ggtagttggt gtgaaactcg gctgtattaa tcacgcgatg
    41821 ttgactgcac aggtaataca acacgccgga ctgactctgg cgggttgggt ggcgaacgat
    41881 gttacgcctc cgggaaaacg tcacgctgaa tatatgacca cgctcacccg catgattccc
    41941 gcgccgctgc tgggagagat cccctggctt gcagaaaatc cagaaaatgc ggcaaccgga
    42001 aagtacataa accttgcctt gttgtagcca ttctgtattt ggttaaattg cgagcgagat
    42061 cgcgtcttcg attgactgca atttaaccaa ttaaattcta aaataatcac gaaaaaaatt
    42121 ttacttccgc ctcatgcggc gaatgtggga attgcccagg cggcggggga taggggctgg
    42181 agacagttat ccactattcc tgtggataac catgtgtatt agagttagaa aacacgaggc
    42241 aagcgagaga atacgcggct tgcacgcgaa ttggcgttaa agacggctca aagaaatatc
    42301 ttttattttt taactggtta gataaatgca atggcagtca ctgaacaggc atctcttgcc
    42361 ataaaactgt catcactcat cttgacaaat gttaaaaaag ccgttgcttt ggggataacc
    42421 cggtaaggcc ggagttttat ctcgccacag agtaaatttt gctcatgatt gacagcggag
    42481 tttacgctgt atcagaaata ttatggtgat gaactgtttt tttatccagt ataatttgtt
    42541 ggcataatta agtacgacga gtaaaattac atacctgccc gcccaactcc ttcaggtagc
    42601 gactcatgag taaaccgttc aaactgaatt ccgcttttaa accttctggc gatcagccag
    42661 aggcgattcg acgtctcgaa gaggggctgg aagatggcct ggcgcaccag acgttacttg
    42721 gcgtgactgg ctcagggaaa accttcacca ttgccaatgt cattgctgac cttcagcgcc
    42781 caaccatggt acttgcgccc aacaaaacgc tggcggccca gctgtatggc gaaatgaaag
    42841 agttcttccc ggaaaacgcg gtggaatatt tcgtttccta ctacgactac tatcagccgg
    42901 aagcctatgt accgagttcc gacactttca ttgagaaaga tgcctcggtt aacgaacata
    42961 ttgagcagat gcgtttgtcc gccaccaaag cgatgctgga gcggcgtgat gtggttgtgg
    43021 tggcgtctgt ttccgcgatt tatggtctgg gcgatcctga tttatatctc aagatgatgc
    43081 tccatctcac ggtcggtatg attatcgatc agcgcgcgat tctgcgccga ctggcggagc
    43141 tgcaatacgc tcgtaatgat caagcattcc agcgtggtac tttccgcgtt cgtggcgagg
    43201 tgatagatat cttcccggca gaatcggatg acattgcact tcgcgtggaa ctgtttgacg
    43261 aggaagtgga acgattgtcg ttatttgacc cgctgaccgg gcagattgtt tccactattc
    43321 cacgttttac catctacccg aaaacgcact acgtcacacc gcgcgagcgc atcgtacagg
    43381 cgatggagga gatcaaagaa gagctggccg ccagacgcaa agtgctgttg gaaaacaaca
    43441 aactgctgga agagcagcgg ctgacccagc gtacccagtt tgatctggag atgatgaacg
    43501 agctgggcta ctgttcgggg attgaaaact actcgcgctt cctctccggt cgtggaccgg
    43561 gtgagccacc gccgacgctg tttgattacc tgcctgccga tgggctgctg gtcgtcgatg
    43621 aatctcacgt caccattcca caaattggcg gcatgtatcg cggtgaccgg gcgcgtaaag
    43681 agacactggt ggagtacggc ttccgcctgc catcagcgct ggataaccgt ccgcttaagt
    43741 ttgaagagtt cgaagcatta gcgccgcaaa ccatctatgt ttcggcgacg ccgggtaatt
    43801 acgagctgga aaaatccggc ggcgatgtgg tggatcaggt ggtgcgtcca accggattgc
    43861 ttgacccgat tatcgaagtg cggccggtgg cgacacaggt tgatgatctt ctttcggaga
    43921 ttcgtcagcg agcggcaatt aacgaacgcg tactggtcac cacactgacc aagcggatgg
    43981 cggaagatct taccgaatat ctcgaagaac atggcgagcg cgtgcgttat cttcactcag
    44041 atatcgacac cgtcgaacgt atggagatta tccgcgactt gcgtctgggt gagttcgacg
    44101 tgctggtagg gatcaactta ctgcgcgaag gtctggatat gccggaagtg tcgctggtgg
    44161 cgatcctcga cgctgacaaa gaaggcttcc tgcgttccga acgttcgttg atccagacca
    44221 ttggtcgtgc ggcacgtaac gttaacggta aagcgattct ctacggcgat aagatcaccc
    44281 catcaatggc gaaagcgatt ggcgaaaccg aacgtcgccg tgagaaacag cagaagtaca
    44341 acgaggaaca cggaattacg ccgcaaggct tgaacaagaa agtggtcgat atcctggcgc
    44401 tggggcagaa cattgccaaa accaaagcga agggcagagg aaaatcgcgc ccgattgttg
    44461 agccggataa tgtgccgatg gatatgtcgc ctaaagcgtt gcagcagaaa atccatgagc
    44521 tggaagggtt gatgatgcaa cacgcgcaga atctggagtt cgaagaagcg gcgcaaattc
    44581 gtgaccagtt gcatcagctg cgtgagctgt ttatcgcggc atcgtaacag gatagcgaag
    44641 aagactgatg acaaacggaa aacagcctga tgcgctacgc ttatcaggcc tacattttct
    44701 ccgcaatata ttgaatttgc gcggtttgta ggccggataa ggcgttcacg ccgcatccgg
    44761 cataaacaac gcgcactttg tcttcaatag gaagccggaa ttttccttcg gatttccgtt
    44821 aacctaaagc ctgtaacgcc ttttccagcg cgttatgtaa caactggcgg tcatgacgat
    44881 acggaatatc gctggcctcc agtacctcct ggatcacaat ccgctctttc accgccgaga
    44941 catccacttt tggcccgacg atgaccgcat caatgacctt tttaccaaca tactgctcca
    45001 taattgccag cttgctttcc agcttcaaat tagccgcagg taaactcaac tcacgcccca
    45061 gattgccgat ataaaccatc ggcgctggcg tgcggcgtaa tgcctgggcg atttccttca
    45121 gcagcagaat tggcatcagg ctggtataaa aactgccagg cccaataatg atgagatccg
    45181 cttcattgat agcgtgaacc gcctcacgcg ttgcgggtac attaggcgtt aacaataact
    45241 cttgaatcgg cgtagttaac tggtcgatat tgacctcgcc gtaaacttca tgcccctgat
    45301 cgtcaatcgc catcagatca acaggatgct ctgacattgg aatcaaatgc gtatccactt
    45361 tcagcagatt acgaattaaa ttgatggctt ccagaggccg cacgctaagg tgatccagcg
    45421 cctttaacat caagtttccg agattatgac cggaaagttc gccattgcca ccaaaacggt
    45481 attcaaacat cgcggaggcg acgctcggtt ccgttatcag ctggttgagg cagttgcgca
    45541 tatcgcccca ggcaatgccg ccttctgaac ggcgaatacg ccccgtcgag ccaccattat
    45601 cggtggtggt gacgataccc gttaaacgag aacccaaaga cgaaagtgat gagagaacgc
    45661 gtcccagtcc atgccctccg ccgagagcaa cgacacgatc aagatcagcc agcgtacgat
    45721 tgcgcatata gtttcctgga gtcagattat ccgcgctaca gtagcgcaaa ttgcggggaa
    45781 acagcaatta acctgccaat attgaggata caaactattt tcttctacct ctaaaggacg
    45841 atgcacgcta tgcctccctg atgatgtata tcaaagtaaa accgccattt tcccttattc
    45901 tgtagcgaaa tagcacgatc atgacgctat atacatgatt acatagcgaa agtgtggatg
    45961 gtaaaaatct catttacacg ctagtatcgg cataaccact aaacactcta gcctctgcac
    46021 ctgggtcaac tgatacggtg ctttggccgt gacaatgctc gtaaagattg ccaccagggc
    46081 gaaggaagaa atgacttcgc ctcccgtatc tggaaaggtg tacatggctt cacaactgac
    46141 tgatgcattt gcgcgtaagt tttactactt gcgcctgtcg attaccgatg tgtgtaactt
    46201 tcgttgcacc tactgcctgc cggatggcta caaaccgagc ggcgtcacca ataaaggctt
    46261 tcttaccgtc gatgaaattc gccgggttac gcgcgccttc gccagtctgg gcaccgaaaa
    46321 agtgcgcctg acaggaggag agccgtcttt acgccgcgac tttaccgata tcatcgccgc
    46381 tgtgcgggaa aacgacgcta tccgccagat tgcggtcaca accaatggtt accgtctgga
    46441 acgcgatgtg gcgagctggc gcgatgcggg acttactggc attaacgtca gtgtcgacag
    46501 tctggacgcc cgccagtttc acgctattac cgggcaggat aaattcaacc aggtcatggc
    46561 agggattgat gctgcatttg aggccggttt tgagaaggtc aaagtcaata ccgtgctgat
    46621 gcgtgatgtt aatcatcacc agctcgacac ctttctgaac tggatccagc atcgccctat
    46681 ccagctgcgt ttcatcgaac tgatggaaac gggcgagggc agcgagctct tccgtaagca
    46741 tcacatctct ggtcaggttc tgcgtgacga gctactgcgt cgcggctgga tccaccaatt
    46801 acgtcaacgc agcgacggtc ccgcgcaagt cttttgccat ccagattacg ccggagagat
    46861 tggccttatc atgccgtatg aaaaagactt ctgcgccact tgcaaccgcc tgcgcgtttc
    46921 ctccattggt aaactccatc tctgcctgtt tggtgaaggc ggcgttaacc tgcgcgatct
    46981 gctggaagac gatacccagc aacaggcgct ggaagcgcgt atttcagcgg cgctgcggga
    47041 gaagaaacag acccatttcc tgcatcaaaa caacaccggt attacgcaaa acttatcgta
    47101 cattggcggc taaaacgtca aaaggagaga tcagatgagt caggtaagca ctgaatttat
    47161 cccgacccgt attgctattc ttacggtttc taatcgtcgc ggtgaagaag acgatacctc
    47221 cggtcactat ctgcgcgatt cggcgcaaga agcgggccat cacgttgtcg ataaagccat
    47281 tgtgaaagaa aaccgctacg ctattcgcgc tcaggtatct gcgtggatcg ccagcgacga
    47341 tgtacaagtg gtattgatta cgggtggtac tggcctgacg gaaggtgatc aggctcccga
    47401 agcattgctg ccgttgttcg accgtgaagt tgaaggtttt ggtgaagtgt tccggatgtt
    47461 gtcgtttgaa gagattggca cttccacgtt gcaatctcgt gcggtagcgg gcgtcgccaa
    47521 caaaacgctg attttcgcca tgccgggttc gaccaaagcg tgccgtaccg catgggaaaa
    47581 tatcatcgcg ccgcagctgg atgcccgtac gcgtccgtgt aatttccatc cacatttgaa
    47641 gaaataagta tgtcgcaact gacccatatc aacgccgctg gcgaagcgca catggtggat
    47701 gtctccgcca aagcggaaac cgtgcgtgaa gcgcgggcgg aagcctttgt caccatgcgc
    47761 agcgagacgc tggcgatgat tattgatggt cgccaccaca aaggcgacgt atttgccact
    47821 gcgcgtattg ccggtattca ggcggcaaaa cgcacctggg atctgatccc gctctgtcat
    47881 ccgctgatgc tcagcaaagt tgaagtcaat ttacaggccg agccggagca caatcgggtg
    47941 cgtatagaaa ccttatgccg cctgaccggg aaaaccggtg tcgaaatgga agcattaacc
    48001 gcggcctccg tggcggcgct gaccatttat gacatgtgca aagcggtgca aaaagatatg
    48061 gtgattggtc cggtacgttt gctggcgaag agcggcggca agtcgggtga ctttaaggtg
    48121 gaagcggatg attaaagttc tttttttcgc ccaggtgcgc gagttggtgg gaacagatgc
    48181 aaccgaagtg gctgcggatt tcccaactgt tgaagcgtta cgccagcaca tggctgcgca
    48241 gagcgatcgc tgggcgctgg cgctggaaga tggcaaatta ctggctgccg tcaaccagac
    48301 gctggtgagt tttgaccatc cgctgactga cggcgacgaa gtagctttct tcccgccggt
    48361 aaccggaggt taagatggca gaaaccaaaa ttgttgttgg tccgcagccg ttcagcgtag
    48421 gagaagagta cccgtggctg gcggagcgtg acgaagacgg tgcggtagtc acctttactg
    48481 gtaaggtgcg caaccataac ctgggcgaca gcgtcaacgc attaaccctc gaacactatc
    48541 cggggatgac tgaaaaagca ctggcagaaa ttgttgatga agcgcgtaac cgctggccgc
    48601 tggggcgcgt cactgtgatt caccgcatcg gggaattatg gccgggcgat gaaatcgttt
    48661 ttgtcggtgt caccagtgcg catcgcagca gtgcgtttga agccgggcag tttattatgg
    48721 attatctcaa aacccgcgca ccgttctgga agcgcgaagc cacgccggaa ggcgaccgct
    48781 gggttgaagc tcgggagagc gatcagcagg cggcaaaacg ctggtagttt tttgttagcc
    48841 ggataaggca ccgctgcgtc cggcaatttc accgctcagt acatacgttt acgctgcgtc
    48901 gatgcacagc ctcatcattt tgcagtatcc ttaagatatt ccttatatct tcaggagatc
    48961 gtcatggaca gattcccacg ttctgattca atcgtacaac cccgggctgg cttgcaaact
    49021 tatatggctc aagtctatgg ctggatgacc gttggcttgt tgctgaccgc atttgttgcc
    49081 tggtatgcgg ctaattccgc ggccgtgatg gagctgttgt tcactaaccg tgtcttttta
    49141 atcggtctga tcatcgcgca attagcattg gttattgtgt tatcagcgat gattcaaaag
    49201 ctgagcgcag gtgtaacgac gatgctcttt atgctttatt cggcgctgac gggtcttacg
    49261 ctttccagta tattcattgt ctataccgct gcttctatcg ccagtacttt cgtcgttact
    49321 gccgggatgt tcggcgcaat gagcctgtac ggttacacca cgaagcgcga tttaagtggc
    49381 tttggcaata tgctgtttat ggcgttaatc ggcattgtgc tggcatcgct ggtcaacttc
    49441 tggttgaaaa gcgaagcatt gatgtgggca gttacctaca tcggcgtgat tgtctttgtc
    49501 ggattgacgg cgtatgacac gcagaaactg aaaaatatgg gtgagcagat tgatacccgc
    49561 gacacgtcga acctgcgcaa atattccatt cttggcgcgt taaccttgta tctggacttc
    49621 atcaacctgt tcctgatgtt gttgcggatc ttcggcaacc gccgttaatt ctttttcacc
    49681 atcactatcc cggccatgtg tcgggatttt tttcttacta aaaacgacac ttaacaagta
    49741 ccaggtataa aatatgcctt atggacgagc ggaagcgttt tctgtatcca taaatgcaaa
    49801 agtattttgt atgcgtggtt ttaaatttat tgatggtgaa tattaatatt ttttctaagg
    49861 ataactaaaa gaatggaatc atactcgcaa aacagcaata aattagattt tcagcacgag
    49921 gccaggatat taaacggtat atggctcatt accgctttag gtttggtggc aaccgcagga
    49981 ctagcctggg gagctaagta tctcgaaatt acggcaacca aatatgattc accaccaatg
    50041 tatgtcgcca tagggttatt attactttgt atgtatggct taagtaagga tatcaacaag
    50101 ataaatgccg ccatcgcggg cgtaatatat ctgtttttac tctctttggt ggcgattgtc
    50161 gttgcaagtt tagttcctgt atatgccatt atcatcgtgt tcagcactgc gggcgcgatg
    50221 tttttaatca gtatgctggc cggtttatta tttaatgttg atcctggttc tcaccgtttt
    50281 atcattatga tgacgttgac agggttggcc ctggtaatca tcgtgaatgc ggcattaatg
    50341 agtgaacggc ccatttgggt aataagttgc ttaatgattg tgttatggtc aggcattatc
    50401 tcgcatggac gaaataagct ccttgaattg gcggggaaat gccatagtga agagttgtgg
    50461 agtccggttc gttgcgcttt tacaggtgca ttaacactct attactattt tatcggcttc
    50521 tttgggatac ttgccgcgat agctataacg cttgtctggc aaaggcatac gcgttttttt
    50581 cattagccgt aaatgcacat actaaagaac ttaactaaac ttcacatcgc cgcttcattt
    50641 ttcgcccgta gcttcttcgc ctggctttcc agcaacaggt aacagatcag cgccagcagc
    50701 agtgggataa agtaatacag cacacggtaa gcgagtaggg cggcgataat tgtacctttg
    50761 gaggtatgct ccccagccag tagtgcgata aacaccgctt ccagcacacc gatccccgcc
    50821 ggaatatgca cgatgacgcc agcaatacta ctaaccagta acacgcccag tacaaagaaa
    50881 tagttcacgc tttgaccaag taacagccag ataatcgccc ccattaccat ccagttaacg
    50941 ctggaaatca gcatctgagc gagggcgaat ttccatgaag gcagcaccag cttttgccct
    51001 ttgatggtca tatggcggtg cttcgcgaaa gcgcaaaacc acaaataaac cgcgataatc
    51061 atcagtaagc caatgccgag aatacgcagc gtagtttgat cgacatacca gtgatccggc
    51121 aactccacca cgcctgcggt aaagataatc cctgccagta aaatgtagcc cagccagttg
    51181 gtggtaatac tgagcgagaa aatccgcata atagtgctac cgggcaaccc cagacgagag
    51241 tacaaacgat agcgcatacc aatgccgccg acccaggtac tgagcgtcag gttgaaggcg
    51301 tagcagataa acgacaccag catcacctgg cgcttcgcca gtttgtgacc gcagtaaaag
    51361 cgggcgagca ggtcatagca gccgtaaatc agatagctga cgaccaccag cccgaccgca
    51421 ctaagcagcg caacgcgatt gtagtcgcgg atgaccttcc agacctcttc ccagtccact
    51481 tttttggcgt agaccaccag caacacaatc accgcgataa aaaacagcca ggtgaggatc
    51541 ttctttgcta agcgccagcg cgggtgtgat ttactcatca gggttttacc cccgtgtttt
    51601 cagtttctac ccgatcctgc gtttccattg tcggttgtgc gggcggatca acctgcgcca
    51661 gacgtggcgt gtgtgccgga agccagccaa ccagcgccgg gaagtggcgt aaaaagtgga
    51721 acgccagcac gcttttggtc aggttccacc aggtgcgttt gggcagcatg gtttcatcca
    51781 cctgctgaca atctgcggca ataatgccgt tcagattatc gcgcagcgtc tggttaaaat
    51841 gacgatcgtg gatgatgaca tttgcttcga gattcagtga caaactgagc ggatcgagat
    51901 tactggaccc tactgtcgcc cagtgatcgt ccatcaatgc cactttgccg tggagcgggc
    51961 ggcggcggta ctcaaaaacc tgaacgccgc ctttaaccag atagttatac agcaagcgcg
    52021 caccgactct gacaatcggc atatccggtt cgccctgaat gatcagtttg atccgcaccc
    52081 cgcgccgtgc cgctttacgc aaggcgtgta aaaatcgata gccggggaag aagtaggcgt
    52141 tggcgataat cacttcccgc cgcgcctgag tgagcatttt caaataatgg cgttcaatat
    52201 catcgcgatg ttcttcgtta tcgcgccaga ccagcaatac ctgcgcttct cccggctggc
    52261 ggttctcttc cgctttgtga tgacgtcgcc accagcgtcg tgccgcgctc tgtccaggca
    52321 ggttttccag ctcaaactgg agaatatctt cgacaatcgg cccttcaagg cgtaccgcgt
    52381 aatcctgttt agcctctgga ccgtagctgg acatatgctc ggcggagtaa ttcagcccgc
    52441 caataaaggc tatacgcgcg tcgatcacca caattttgcg atgcatccgg cgaaacacat
    52501 tggtgcgcat accaaaaagg cgagggcggg gatcgtagta gcggaacact acgccagctg
    52561 ccgtcagttc attgacaaac tcatcgctga gatccggcga accgtagcca tccagcaaga
    52621 cttccgcttt aaccccgcgt tgcgctgctg ccagtagtgc cgcatgcagt tgtttgccga
    52681 cgtcatcctc aaaccagata aacgtttcaa gaatgatgcg ttcttgtgcc tcgccaatcg
    52741 ccttaaacac cgcgggataa tattgctcgc cgttttccag caactggatc ttattgcctt
    52801 cgcgccagct acatttcata aatgaatctc cgcacttaaa ggggcatgat cagaaaggtg
    52861 tcgccatgtc cgcagcggca acgcggttgg cgcgctggcg ctggcatttt tgacgtagat
    52921 cctgtccagt cgtagtagag gaaattgcac cggaaacgtg cgcgccgggc gtccgtgggc
    52981 gcgggtaaaa atctcatcca gtccggcctg cacttttaac ggatgattag ctttttgccg
    53041 ccagtcattg aaatcacccg ccaccaatac cggttcgccg tccggtagct cattcaccca
    53101 ttcggcgagc atcgcaagct gcgcctgacg gtgcgcctca cgcaggccca gatgtacgca
    53161 catcacatga atcgcttttc cggtcatcgg cggcacaatg cggcagtaga gcacgccgcg
    53221 cttttccgca ccatcgaccg aaacatcgcg attctcataa tgttcaatgg gataacgcga
    53281 cagtacggcg ttgccgtgat gcccttccgg gtatacggca ttgcgaccgt aggcaaaatc
    53341 gctccacata gtgtcggcga gaaactcgta gtgcgaggta tcgggccagt tttccacatg
    53401 cagcggatga acttcgtgcg cgcccatcac ttcctgcagg caaacaatat cggcgctgac
    53461 ggtacgcacg gcgtcgcgaa gttccggcaa aatgaagcgt cggttaaacg cggtaaagcc
    53521 tttgtgaata ttgatggtga gcaccttgaa cgaaaattgt tgtgtttgat cgggcataat
    53581 tttcctgtct ttgcctctta tctcattgaa atagtgtagt cggcgtcaca aaaaggtgcg
    53641 gtcttacgga attttccgta aagttcggta ctctgagtaa gtagagataa attattcagg
    53701 agagaagcca tgaagtggca acaacgtgtt cgtgtcgcaa cgggtctaag ttgctggcag
    53761 attatgttgc atttactggt agtggcgctg ctggtggtgg gctggatgag taagactctg
    53821 gttcacgtcg gcgtgggatt atgcgcactg tattgtgtca cggtagtgat gatgctggtg
    53881 tttcagcgcc accccgagca acgctggcgt gaggtggcag acgtgctgga agagctgacc
    53941 acgacctggt attttggcgc agcgctgatt gtgctgtggc tgttgtcccg cgttctggaa
    54001 aacaactttt tgctggcaat tgcagggctg gcaatccttg ccggcccggc ggtagtgtct
    54061 ttgctggcga aagataagaa gttacatcac cttacgtcta aacatcgcgt acgccgctga
    54121 ccctgtcgtg gccgttatca ccagtagcgg ccacaaacta ttccacacaa tatccagact
    54181 cgcatccttc aaataaatct gcttggtaat gtccgtaaag tggcgaatag ggttaatcca
    54241 cgtcaggttt tgcagccata ccggcatgtt ttccaccgga gaaacgtaac cggaaaggag
    54301 aatggcgggc atcataaaga caaacacgcc gataaacgcc tgctgttgtg ttgaacagag
    54361 tgatgaaatc aacagaccga atcccaccag cgataaacca taaatcacca tcgtaaagta
    54421 gaacagcgcc agcgatccgg cgaaggggat ttgatacgcc cagataccaa tcgccagcac
    54481 aatggtggcc tggaaggtgg cgacaattaa cgccggtacg gctttgccga tgaagatctg
    54541 ccaggtggtg agcggcgaaa ccagtagctg atcgagcgta ccttgttcac gttcgcgggc
    54601 gacggaaagt gaagtgacga tcattacgcc gatagtggtg atcatggcga tcagtgacgg
    54661 caccacaaac catttgtagt cgagattcgg gttataccag ttgcgtacca ccagctcgct
    54721 gttgttaggt ttcggttttc cttccagcag ctcctgctga taatttttga cgatctgttg
    54781 caggtagttg gcggcaattt gcgcactgtt ggagttacgc ccgtcgagga tcaactgcaa
    54841 aggcgcggtc tggaaggtat ccagtttgcg cgagaagtca gccgggaaac gcaccagtag
    54901 taacgccttt tgtgtgtcga tggttgggcg gatctcctgt gggcttttca gcagcagcac
    54961 atgagtaaag gcgctggcgc gggcaaaacg ttgggtcagc tccaccgaat gctcgccgtt
    55021 atcttcatcg tagatggcga tggtggcgtt agtcacttcc agcgtggcgg cgaacgggaa
    55081 caggatcacc tgaattagca cgggtaaaat cagaatcgcg cgggtttgcg gttcgcgcag
    55141 caacgactgc aactctttgc ggattaacgt ccataagcga tgaaacatgc tcttctccct
    55201 aatccagccg acgtttggtt ttcagccacg tcaggccgat aaacatcacc gccgaagcga
    55261 tcaaaaacag cacgtttacc accagcacca ctggaatatt cccggcgagg aacaggcttt
    55321 gcagggtgct gacgaaataa cgagcgggaa taatgtacgt caccgcgcgg atcaccgcgg
    55381 gcatactgtc gatctgaaaa ataaagccgg aaagcataat cgacggcaga aaagcggcgt
    55441 tcagggcgac ctgagcggca ttgaactggt tgcgggtaat cgtggaaatc agcagcccca
    55501 tccccagggt actgagtaaa aacaggctgg agataaaaaa cagaatcagc agcgacccgc
    55561 gatacggcac gccgagaata aacactgaca ccagcataca cagcaacatc gccagcatcc
    55621 cgagaaagta ataagggatc agcttacaca gcagcagttc cgtgcgggta atctccgtag
    55681 agagcagagc ctccatggtg ccgcgttccc attctcgcgc caccaccagc gaggtgagaa
    55741 tcgcgccgat gaccgtcatg ataatggtca ccgcaccggg gataatgaag tgctggctaa
    55801 tcgccgccgg gttaaaccag tagcgggttt gtacatcaat aagcggttca aaagtctgcc
    55861 cgttgtcctc cgctcgctgc atttgccaga tctgccagat cccttcgaca tacccctgta
    55921 caaagttagc ggtattcggc tcactgccgt cggtgatcac ctgaatcggt gcggtggcgt
    55981 tggcgcgctc catctgttcc gcaaaatcca ccggaataac caccagaccg cgaattttcc
    56041 ccgcctgcat tttggcgatc agttcctgac ggttatcgct gatggtggcg tcgatgtagg
    56101 gcgaaccggt catggtgtgg gtgaaatcca gcgccgcttc gctacgctgt tccagtaaaa
    56161 tcccgacccg cagcttgctg gagtcgaggt taatgccgta accaaaaata aacagcagta
    56221 gcagcgggat cactaccgca atcagccagc tactcggatc gcgaacgatc tgccgcgtct
    56281 ctttaacgca cagcgcccgt acgcgacgcc aggacaggat cgggttactc attgctatgc
    56341 tccttatccc agtcgtggat caactgaata aaggcttgct ccatggtggg atcgggttgc
    56401 tcatcgttag ccgactgtgc tttcaaatcg tccggcgtgc cgctggcgat taatttcccg
    56461 cggtacacca ggccgatgcg gtcgcaatat tccgcttcat ccataaagtg ggtggtgacc
    56521 atcaccgtga cgcctttctc taccatgctg ttgatgtgca gccaaaattc acggcgggtg
    56581 agggggtcaa cgccggaagt cggttcgtcg agaaacagaa tgtccggttc atgcatcagc
    56641 gaacaggcca gcgccagccg ctgtttaaaa cctaatggca gttcatcggt ggcgtgggag
    56701 gcgatacttt tcaggccgaa cgcctcgctc atgcgggaga ttttttcgtt ctgcgcccga
    56761 ccgcgtaagc catacacacc agagaaaaag cgtaaattct gttcgaccgt caggttaccg
    56821 tagagcgaaa atttttgcgc catatagccg agatgctggc gcgctttacc ggaactctct
    56881 ttcagatcca tccccagcac cagcgcctgg ccggaagtcg gcaccagcaa accgcacatc
    56941 atcttaaagg tggtcgattt acccgcgccg tttggcccca gcaaaccaaa aatctcccca
    57001 cgtttaacgg caaagttgac gtgatcggtg gcggcaaaat ccccaaattt cttggtcagt
    57061 tctttcgctt cgatcaccgt ctcgccgggt gtgccttcta ccgtatgtaa tattgcgccc
    57121 agcggcgatt ccgaggttcc ggcaccgccc agcaaatcaa taaacgcatc ttcaaaacgc
    57181 ggcgtagttt cgttgatgtt gatttccggc atcccgtcgg catggcgaat atcgtctggt
    57241 gtggcctctt ttttgaggat cagacgtacc gatttcccct gaatcatgcc gtcgctgacc
    57301 tgcggcagtt tcaaggcgcg ttgcaacagt ttgcggttgc cctcgtgtgg actggtcatc
    57361 agaaagctgc gtccggccat ggtttgtgtc agggcttttg gtcctccctg atacagcaac
    57421 tcgccttcgt tcatcagtaa cacgtcacgg cactgctcgg cttcgtcgag atacgaggta
    57481 ctccagagga ttaacatccc ttcgcccgcc agctcatgca ccatctgcca cagttcgcgc
    57541 cgtgagatag ggtcaacgcc gacgccgggt tcatcgagca gcaacacttt cggttcgccc
    57601 accagggtac aggccaggcc gagtttttgt ttcatcccac cggagagctt gcccgccagg
    57661 cgtccggtaa acggcccaag agacgtaaac tccagcaggc gagcaaaagt ttgcttacgt
    57721 gcctcgccgg tgacgctgcg caaatccgcg tacagattga ggttctccat caccgtgaga
    57781 tcttcataca gaccaaattt ctgcggcata taaccgagca cggcgtgcag cgcgccgtcg
    57841 tttttgatcg gatcaaagcc aatcaccgtg gcactgccgc tgtcgggttt cagtaatccc
    57901 gccaacatcc gcatcagcgt ggttttacct gcaccgtccg gccccaccaa ccccgtcaca
    57961 taaccggcgt gaatggtaca atcgagcggc gcgacggcgg gcttgtccat gcccggaaag
    58021 cgtttttcca ggccgttcag cgtgataacg gcatcattca tgtcctgcct cgtcaccgaa
    58081 ttgtaccgtc actggcattc cctggcgtaa cgcatcatcg gcgtcggtca ccacaatacg
    58141 caggcgatag acgaggtcgg tacgcagatc cggcgtttcg acggttttcg gggtaaattc
    58201 agcagtcggc gaaacgaaac caatctgccc gtgatacggc ttgtccgggc gaccatcggt
    58261 ataaagcagc actttgcgcc ccggctgggc ctggtcaaga ttacgttcat caacataagc
    58321 gcgcacccac accggacgcg ttagtgaaac ggtaaacacc gtgccacctt cattgaggac
    58381 cgtgcctggc tccaccgcgc gcgttaacag cgtgccatca gacggggcta tcaacgttga
    58441 gtcctgtaaa ttcaactccg cctgcgccag ttgcgcctgc gcctgttcga ggctggcttt
    58501 cgcctgagcg atgtcctgtt cacggttacc ggaacggtac tgacgcaatt tatcctgtgc
    58561 tgatttcagc gttgcctgcg cctggtcgcg cgaggagcgg gcattttcca ggtcatttgc
    58621 cgaaatagtg cggcttttcc acaacccttg ctggcggtta tagaagttct gcgcatagtc
    58681 ataggcggct tgcgcctgtt tcaccgctgc ggcggcctga gcgatttctt catcgcgata
    58741 cccggcaagc atcaggtcat actgcgcctg tgccaccgaa acacccgctt tcgcctgcat
    58801 cagggcaatc tcatacggct tgtgatccag ttcgcccagc acctggcccg ctttgatagc
    58861 atcaccttcg tccaccgcca gcgattcaac gcgcccccca acacggaaac taagatttac
    58921 cgtacgaata tccacgttgc catacagcgt caggccgtta tcctggcggc tttgatacca
    58981 ccagtagcct ccggcaacca cggcggcaag taccactacc gccaatccga tcacgacagg
    59041 ttttttcatc actacaaact cctttgcgat aatccttgca aaatcaggtc gatatgacag
    59101 gtcaccgtct ggttgatcag ttcggtcttt tcttcatcga acgcggtcca gccggtacgt
    59161 aacagaattg tttctttgcc aagacggaac gccagaatct caccaatcaa cgcatgggta
    59221 tgaaggatca tgcgggtgtc attggcgtcg cagccggtcc aggcggcaat caggcgtgtc
    59281 aggtggctgt gtagcggact aatcacctgt tcgtgcacca ggtggtaggc tgccgtggga
    59341 gagagctgct cacgggagat aaacttgctg aggttgacgg tgtcatcctg ggtgagcagc
    59401 ttaatcatgt tcctgcaggc gcgaaggatc agttcacgga tggcagcccg atcaggctgt
    59461 ggttgcgcga acaagcgttc ggcttcctcg gcatgcggac ggaactgctc gccaataaaa
    59521 tcggcaatcc actgggcgca ggcgaggtac aaatcttctt tcgaaccgaa gtagtaggtg
    59581 atggcagcga tattctgccc ggcctgggcg gctatctcgc gagtggtggc gttcattcca
    59641 tattcaccaa actgcgccag tgcggcagca atcagctgtt ttttcgcctg ttcacccttg
    59701 attgtcatgg caggattatt catcgcacag tccattctta atcaaatgat tgattaagat
    59761 tatgactcca taggggagtt gtccagtatg gctaagaatt ttagcaacgc cagtcacagg
    59821 gataatttat gcgctgcgtc acaaaaactg ctacactccg ctccctcatg acattgtggt
    59881 ttttgtcatt ttccttttca gtatctccct gaaaactaca ccggtaacgg tcggggcggt
    59941 tcggagtagt tatgtctttc gattctttgg gtttaagccc tgatatcctg cgcgccgttg
    60001 ccgagcaggg ttaccgtgaa cccaccccta ttcagcagca ggcgatccct gcggtgctgg
    60061 aaggccgcga cctgatggct agcgcccaga ccggcaccgg caaaacagcg ggctttacgc
    60121 tgccgctgtt gcaacacctg atcactcgcc agccgcacgc caaagggcgt cgtccggtac
    60181 gtgcgctcat tcttaccccg acccgtgaac tggcggcgca gattggcgaa aacgtccgtg
    60241 attacagcaa atacctgaac attcgttcgc tggtggtgtt tggtggtgtg agtattaacc
    60301 cgcagatgat gaaactgcgt ggcggcgttg atgtgctggt ggcaaccccg ggacgtttgc
    60361 tggacctgga acatcagaat gcagtgaagc tggatcaggt tgaaatcctc gtcctcgatg
    60421 aagctgaccg catgctcgac atgggcttta tccacgatat ccgtcgcgtg ttaacaaaac
    60481 tacctgcgaa gcgccagaac ctgttattct ccgcgacctt ctctgacgat attaaagccc
    60541 tggcggaaaa actgttgcac aacccgctgg aaatcgaagt ggcacgccgc aataccgcgt
    60601 ctgatcaggt gacccagcac gttcactttg tcgataagaa acgcaaacgc gaattgctgt
    60661 cgcacatgat tgggaaaggg aactggcagc aggtgctggt gtttacccgt accaaacacg
    60721 gcgctaacca tctggctgaa cagctcaata aagatggcat ccgtagtgcg gcgatccacg
    60781 gcaataaatc gcaaggtgcg cgtactcgtg cgctggctga ttttaaatcg ggcgatattc
    60841 gtgtactggt ggcaactgac atcgctgcgc gcggcctgga tattgaagag ctgccgcacg
    60901 tcgtcaacta tgaactgcca aacgtacctg aagattatgt ccaccgtatc gggcgtaccg
    60961 gtcgtgcggc tgctaccggt gaagcgttgt cgctggtgtg tgttgatgaa cacaaactgc
    61021 tgcgtgatat cgaaaaactg ctgaaaaaag agatcccgcg cattgcgatt ccgggctatg
    61081 agccggaccc gtcaatcaaa gccgaaccga tccagaacgg tcgccagcaa cgtggcggcg
    61141 gcggtcgtgg gcaaggtggt ggtcgcggtc aacagcaacc acgccgtggg gaaggtggcg
    61201 caaaatctgc aagcgcgaaa cctgcagaaa aaccgtctcg ccgcctcggc gatgccaaac
    61261 cggcaggcga acaacaacgt cgccgccgtc cgcgtaaacc tgccgctgcg cagtaatctt
    61321 ttatgccggg ctatgcccgg catcaggctg atgaacaaac gcaaaactgc ctgatgcgct
    61381 acgcttatca ggcctacgtg aactctgcaa tatattgaat ttgcatgctt ttgtaggccg
    61441 gataaggcgt ttacgccgca tccggcattt cacaacaagc acttgtcagc aatttgagaa
    61501 cacgggaaaa aatttatctg ttttaccgcc cataagccac cgagacgtta cttctctata
    61561 gccaattgtt cgcgcaactc cattaaaagg tagcccagtc gattcttgcc cttaccatga
    61621 ccaccgtctc cccagtaagc atcgttttcc gtatgctcaa ccagttttgc gggcgcggtt
    61681 gccagcaaga gcgcacgcag ttctgcatgc tgttcgaatt tagcgcgaag tgcttttcgc
    61741 atcacctgtt ctttgaccga ctcccagttt ttacgcagag gcttagaacg atcgcgcccc
    61801 atgcgtgcgg cgaccatagg ggaagaaacc cgacggatct cttcgcggta tttttcatca
    61861 aggaattttt gtgcctgaaa atagtgttct gaggtgggcc aggttttccc gtcaaccttg
    61921 atgggccagg cggcaaagtt agaaaaatca ccgtagtcat cgctggtgct gtagaaattt
    61981 atgatggtgt cttgcatgac gtgttggatc ctttgtgctc gaacgggcat taaaccgcat
    62041 tatgttggtg gttattgcga gccgctttcc agaaacagaa aaaccattac ccctgaaaac
    62101 cgaaaaatgc cacaatattg gctgtttata cagtatttca ggttttctca tggcattaac
    62161 cgccgcgctt aaagcgcaaa ttgccgcctg gtataaggcg cttcaggaac agatccccga
    62221 ctttattccc cgtgcgccgc agcggcagat gattgcggac gtcgccaaaa cgctggccgg
    62281 agaagaaggg cgacatctgg cgattgaagc ccccaccggc gttgggaaaa cgctctctta
    62341 tttgattccc ggcatcgcca ttgcccgcga agagcaaaaa acgctggtgg tgagtaccgc
    62401 caacgtggca ttgcaggatc agatttacag caaagattta ccgctgctga aaaagatcat
    62461 tcccgatctt aaattcactg ccgcttttgg gcgtgggcgc tacgtttgtc cgcgtaatct
    62521 gacggcgctc gccagtactg aacccacgca acaggatctg ctggcgtttc ttgacgacga
    62581 actgacgccg aacaatcagg aagagcaaaa acgttgtgcg aagctgaagg gcgatctcga
    62641 tacttataaa tgggatggtc tgcgcgatca tactgatatc gctatagatg acgatctctg
    62701 gcgtcgttta agtaccgaca aagccagctg cctcaaccgc aattgttact actatcgtga
    62761 atgcccgttt tttgtcgctc gtcgggagat tcaggaagcg gaagtggtgg tggcaaacca
    62821 tgcgctggtg atggcggcga tggaaagcga agcggtattg cctgacccga aaaatttact
    62881 gctggtgctg gacgaaggcc atcacctgcc ggatgtggcg cgggatgcgc ttgagatgag
    62941 cgccgaaatc accgcgccgt ggtatcggct acagctggac ttgttcacga aactggtcgc
    63001 tacctgcatg gagcagtttc gcccgaagac catcccaccg ctggcgatcc ctgaacgttt
    63061 gaatgcgcat tgtgaagagt tgtatgagct tatcgcctcg ttaaacaaca ttctcaatct
    63121 ctacatgcct gccgggcagg aggcagagca ccgttttgcg atgggcgaac tgccagatga
    63181 agtgctggag atctgccagc ggctggcaaa actcaccgag atgctgcgtg gcctggcgga
    63241 gttatttctt aacgatttaa gtgagaaaac cggcagccat gacattgtac gtctgcatcg
    63301 gttgattttg cagatgaacc gcgcgttggg gatgttcgag gcgcaaagca aactctggcg
    63361 gctggcttcg ctggcgcaat cttccggtgc accggtgacc aaatgggcga cgcgggaaga
    63421 gcgcgaaggg cagctacacc tctggtttca ctgcgtggga atacgtgtca gcgatcagct
    63481 ggaaaggctg ctgtggcgca gtattccgca cattattgtc acctccgcaa ccttgcgttc
    63541 gctgaacagt ttttcgcgtt tgcaggagat gagtggtctg aaagagaaag cgggcgaccg
    63601 ttttgtggcg ctggattccc cctttaacca ctgcgaacag ggcaaaattg ttattccccg
    63661 gatgcgcgtt gagccttcca tcgacaacga agagcagcat attgccgaaa tggcggcctt
    63721 tttccgtaag caggtggaga gcaaaaaaca tctcggtatg ttggtactgt ttgccagcgg
    63781 acgggcgatg cagcgctttc tcgactatgt gacggattta cgtctgatgt tgctggttca
    63841 gggcgatcag ccgcgttacc gtttagttga actgcaccgc aaacgcgtcg ccaacggtga
    63901 gcgcagcgtg ctggtgggct tacagtcatt tgccgaagga cttgatttga aaggtgatct
    63961 gctcagccag gtgcatatcc acaaaatcgc ttttccgccc atcgacagcc cggtggtgat
    64021 caccgaaggg gaatggctga aaagcctcaa ccgctatccg tttgaggtgc aaagcctgcc
    64081 gagcgcctcg tttaacctga ttcagcaggt tgggcgactg attcgaagcc acggttgctg
    64141 gggcgaagtg gttatctacg acaaacgctt gctgaccaaa aattatggca agcgactact
    64201 ggatgcatta ccggtatttc cgatagagca accggaagtc cctgaaggta tagttaaaaa
    64261 gaaagaaaaa acgaaatccc cacgccgtcg gcggcgttaa tgatgtgagt caggtaagga
    64321 gtcgtaaatg gactatcgca aaatcattaa agagatcggg cgcgggaaaa accacgcgcg
    64381 cgatttagac cgggatactg cgcgcggtct gtatgctcat atgctcaatg gtgaagtccc
    64441 tgaccttgag ttgggcggcg tattgattgc gctgcgtatc aaaggagaag gggaagcaga
    64501 gatgctcggc ttttacgaag ccatgcaaaa tcacaccatc aagctgacgc cgccagcagg
    64561 caagccgatg ccgattgtca tccccagtta caacggcgcg cgtaaacagg ccaacctgac
    64621 gccgttgttg gcgattctcc tgcacaaact cggttttcct gtggtggttc acggggttag
    64681 cgaagatcca acccgcgtgc tgactgaaac catttttgaa ttgatgggta ttacgccaac
    64741 gttgcacggc gggcaggcgc aggcgaagct cgacgaacat caaccggtgt ttatgccagt
    64801 cggcgcgttt tgcccgccgc tggaaaaaca actggcgatg cgctggcgga tgggcgtgcg
    64861 taacagtgca cataccctgg cgaaactggc gacgccattt gccgaaggtg aggcgctgcg
    64921 tctttccagc gtttcgcatc cggaatacat tggacgcgtc gcgaagttct ttagcgatat
    64981 cggcgggcgg gcgctactaa tgcatggtac tgaaggtgaa gtgtatgcta atccgcagcg
    65041 ctgcccgcag atcaatctca ttgaccgtga agggatgcgg gtgctgtatg aaaaacagga
    65101 cactgctggt agcgagttac tgccacaagc aaaagatccg gaaaccacgg cgcagtggat
    65161 tgagcgttgc cttgctggca gcgaaccgat tcccgaatcg ctgaaaatcc agatggcttg
    65221 ctgcctggtg gctacgggtg aagcggcaac tatcagcgac ggcctggcgc gcgttaatca
    65281 ggcattttaa ttcttttctc agccggatga gccatgtcat ccggctttta ccccaccgca
    65341 atatgaaatt cctgcatctt tattgacctt cccacgcccg gcgtgcagca taaaaataca
    65401 acaaacacat aacataaaca ggagttaacc atggaaagtg gtcatcgctt tgatgctcag
    65461 acgctgcaca gttttattca ggctgtattt cgtcagatgg gtagcgagga acaagaagcg
    65521 aaattagttg ccgatcattt aatcgcggca aacctggcag ggcatgattc acatggtatt
    65581 ggcatgatcc caagctatgt acgctcctgg agtcaggggc acctgcaaat taaccatcat
    65641 gccaaaaccg ttaaagaggc gggggcggcg gtcacgctcg atggcgatcg cgcatttggt
    65701 caggtcgcgg cacatgaagc gatggcgctg gggattgaga aagcgcatca gcacggtatt
    65761 gccgccgtgg cgctacataa ctcgcatcat atcggccgta tcggttactg ggcggagcag
    65821 tgtgcagcgg cggggtttgt ctctatccac tttgttagcg tggtcggtat tccaatggtc
    65881 gcgccgttcc acggtcgcga cagccgcttt ggcaccaatc cgttctgtgt ggttttccct
    65941 cgtaaagata atttcccgct gttgcttgat tacgccacca gcgccattgc atttggcaaa
    66001 acccgcgtcg cctggcataa aggcgtcccc gtgccgccag gttgcctgat tgacgttaac
    66061 ggcgtgccga cgaccaatcc ggcggtaatg caggagtcgc cgttgggttc gctgttgacc
    66121 tttgccgaac ataaaggcta cgcccttgca gcgatgtgtg aaattcttgg cggggcgctt
    66181 tccggcggta aaacgacgca tcaggaaacg ttacaaacca gtcccgatgc cattcttaac
    66241 tgcatgacca ctatcatcat caacccggaa ctcttcggcg cgccggattg taacgcgcag
    66301 accgaagcct ttgccgagtg ggtgaaagcc tcgccgcatg atgatgataa gccgattttg
    66361 ctaccgggcg agtgggaagt gaacacgcgt cgcgaacggc agaagcaggg gattccactg
    66421 gatgcgggaa gctggcaggc catttgtgat gcagcgcggc agattggtat gccggaagag
    66481 acgttgcagg ctttctgtca gcagttagcc agctaaaaaa aagcccgtcc agtggcggac
    66541 gggcaaacaa gggtaacata ggatcaatga gggttagagc atatgcgtct gtcggcaaac
    66601 agacagggaa atacttgtgc tggacgtagc gtaaacgcct gatccgtcca acggttcgga
    66661 ttttgtaggc ctgataagac gcggtagcgt cgcatcaggc atctgttgcc ggatgcggcg
    66721 taaacgcctt atccgtccta cgaattactt ataaattacc gcagtaccgc ttaatttatt
    66781 gttgttggtg gcggaagtga tgctgtatcc actggcaccg gctgccgcgg ctttctcagc
    66841 cagtttcgct tccagggcat cgagggtgga tgcgccatcg gcagaaacca cgccgatttt
    66901 attcatgttc tgtgcctggg atgccgttac cggttccgcc gcgaacacgc caaatgacag
    66961 agttgaaaga gccatagcag caacaacagt attgatagtt ttcataatta atctctcgca
    67021 ggtgattttt gtataagtga cgttgtttcg tcgatgtgat gagtatcacg tttttttacg
    67081 agagataaaa tcgaagagaa ttgaccgcct tgttcaaata aattgattga tatctaacct
    67141 actgataaac catttatttg ttgtacttat gaacttgttt tataccgcgt ggcagtcaca
    67201 gcagcgttaa aggcacggaa tgacacgcaa aatacaaatt atactcgcta tgcatctcgc
    67261 cagttgtagt taacgtaact ggctgtcttt cgaacctctg cgattatatc ctgtataagc
    67321 tggtttttgt aaatctttct cctgctgaca atgaatacat aagcgcacgc caggaatggc
    67381 ttcccgacgg gcctgcggga tgggggcacc gcactcttca cattcatcca ggctttcgcc
    67441 gcgcggaatt tcaccccgag cgcgggcaat cgcatcttca attgtactgt tgatctgttc
    67501 gttgacggcg tcatcgttag cccaaccgga tgccatatcg acctccccat atcaatactt
    67561 gtacagttaa gtgtagctaa tccagggacg aactcgggca gttcaagcat cagatctccg
    67621 accattcccg cagcagatta tgataaagat taagcagcga caggatctct tcactttcgc
    67681 cgtagcggct tttcagcgac tgaatattgt tgtccagttc aaacagcatg gcgcgctttt
    67741 tatcatcgcg gatcatcgac tggatccaca taaatgatgc cactcgtacg ccgcgggtta
    67801 cgggtgtcac gcaatgcagg ctgctggagg gatacaacac gagatcgcct gccgggagtt
    67861 ttacccgatg ttgtccgaag gtgtcattaa cgaccagttc gccgccgtcg tagctttgtg
    67921 gatcgcttaa aaacagcgtg gcagaaaggt cagtacgcat ccagccgttt tgtggatggc
    67981 tgcgtactgc gccatccaca tggaaaccat aggtttcatt gttctgatag cgattaaaca
    68041 gcggcgtgga aagggtacgc ggcaaggccg cggcaaagaa taaagcatgt tggttaaccg
    68101 cgttcagcac ctcattttgc agggcggcgt ataacgtgct gcgggtgtcg acctgttgat
    68161 tgttcttaac ttgcgcacct tgtgcgccgg tggtgacgcg tccatccacc cattcggctt
    68221 gttccagttg ttcgcgaaaa cgagcgacgt cctgtggcga taacacgccg ggaatgtggt
    68281 acatcataca atttctccaa aaagtggggc ctgcgcccca catctgaatc agaaatgcat
    68341 attggctgtg agcaagaagg ttcttggctc gcccgggtga taacggtagc cgctcttgtt
    68401 gattgaggcg acgtaatcgg tatcaaacag gttgtaaacg tttagctgga agtcgagatt
    68461 gcgattaact cgatacccca gtttggcatc ggcgacccag taaccttcgg taaacgctgg
    68521 cgttcccacc gcgccgtctg aacctttatg catactgccg atatagcgtg cgcccgcgcc
    68581 aacagagata tcgtcggttg cctgatattg gctctataag gtgaaggcgt gctccggggt
    68641 atacggcagc gatgaggaac catcctgggc aacatctttg ccgtttttga tggttgcttt
    68701 ttgctgggta tagccgccaa tcacctgcca cgcgggagtg atattcccgg ccacggatat
    68761 ctcatagcct tcgacgcgtt tcttaccgta ttgcgagtaa gttccgtcat cattttgctc
    68821 aacttcattt tcgatatcag tgcggaacag cgcggcggtg agcaacagac gtttatccag
    68881 aacctgccat ttggtgccaa tctcgctggt gttggctttt tgcggtttaa aatcggtgcg
    68941 gttggcactg ttaccgctgc cagactgcgc aagggcgaag ttgttgccgc ccggaggctg
    69001 ctgggaaacg gcatagttaa tatagacatt gccgttttcc gtcaggtgat acagcgcccc
    69061 ggctttccag ttcatcagat tgcccgactt ggcggtgtcg acggtggtga ccggagaacc
    69121 ttttgccaca ccagttgggc aggtgatggc accgcgtccg ctgccgccgc aggcggtggc
    69181 actgtcatat tcagtatgat aattatccag acggatcccg ccgttcagct caaaatcacg
    69241 ggtgatttgc agcgtatcaa aggcgtaaat tgcgaaggta tccgtctgac cattggcgtt
    69301 tgcgccgttg cgcgtcaggc cgccgggatg aatgctgctg tcaggatgat aaatatttac
    69361 cgcgggtaac gtcaccggat taacgccgta gttagtctgc gtttcacggg taaattccac
    69421 gccggtactg acatcatgac cgatagaacc ggtatagaac gtcgaggtca ggttggtctg
    69481 gttggtgaga attttattac tcacatcttt ggtattcgcc gtgcgtgacc aggtccagct
    69541 attcacatcg ctggtgggct gagtaatatt cgacgccccg cccataatcg ccgtcatcag
    69601 gtaatcctgc tttacgcgcg accaacgggt agtattgcga atggtggtgt tatcgttgat
    69661 gtcgtgctca aaacgcatgg tggcggtgtc ggtggtcgaa tcgtcgtaat cggaatccgt
    69721 gccgtaaaag ttatgagtat caacttttcc ggaatgattc agggccgccg ttcccgcaga
    69781 tggggcagaa tagcccggca aaccgatggt cggaatgccg ccgtctggcg tgttgtgctg
    69841 ggtgacatgc agataattaa gatacaaacg attcgctgta ccaaggccaa aagcgacaga
    69901 aggggcgacg ccgtaacgct catttttgac tttgtcgcgt ccggcatcgt gcgttttttc
    69961 gcccattaca ttcaggcgca ccgcggtggt atcaccaatg acctgattga cgtccagcgt
    70021 gccgcggcgg aaccaggcgc tgccaatact ggcggaggcg tcaatgccgg aatcattgcg
    70081 cggctgcttg ctgatcatat tgatcgagcc tgtcggtgcg ctgcgcccgt agtcggtgcc
    70141 ggacggccct ttaatcactt cgacctgctc ggtattgaag gtgtcgcgcg agacgctgcc
    70201 gatatcgcga atgccatcaa tataaatact gttagaggta tcggcaccac gcatataaat
    70261 ggcgtcgcca gtggtggagt taccgttctc acccgcaaaa aacgcaccca cgccggggac
    70321 gtttttgagc gcgtcggtaa ggttggttgc gccctgatct ttaatcactt gttcagaaat
    70381 taccgtcatc gtgcgggtag tatccgctac cggacgcgag aatttcggat cggcagattg
    70441 ttgtggcgca taaagcgaag gcgttgatgc ttcgacaacc agcgtgtcat ccgcgttagt
    70501 ttgcccttcg gcggcgagtg cctgagccac aggcgtgatg ccaatacaaa gaccggcaaa
    70561 gaacgtgagc gaatgaaatt gtctggcagg gaaattgcga ttgttttcca ttttgcaggt
    70621 gactttttct tatatgttga aattttcact gccacgagaa agcctctctg cggatgcgat
    70681 gccactgtta atcccgtgat agtgctcgtg aaagtgataa taattttgat aagcattatc
    70741 acttggagcg attttctatc acccattgcg cgaaaaagaa atacatttat ttacattgag
    70801 ttcatatttg atgttttttg attacaaaac agacgaaaac tgcatccaga ggcgaatgca
    70861 gttacgttgg tggggttatt tgtagatggt tgcagtaccg aacatctggt catttccgcc
    70921 tgcggaatta atgacataac ctttcgcgcc ttgttcgcgc gctttttctg ccagtttatc
    70981 ctccagatcg cttaggtttg atgcgccagt tgccgaaacg gtaccggcgg gccgtagctg
    71041 accgctgtcc aggttactca tcggttgcgc ggcataagcc gtgagagaga ttccgctcag
    71101 gacggtggca atcagtagtg tgaggcactt tttcataatg acatcctcat aaatacaacg
    71161 ggtagtgcct gataagtgta ggtcgcctgc gcgatgcaaa tgacgcaaaa aattgacaga
    71221 gatgtgctta ttttttgaac gatatatttt tacaaaataa gacaaatcaa tgacatgcat
    71281 aatgctgatt tttatgatga attgccataa accatagcca tgttaaggtt ttggggaatg
    71341 ataaacgcag ccagatattt accctgtcgc gttatgcggg tatcttacgc cgctgcttaa
    71401 aggagaatgc tatgtccgcc cagaaaccgg ggttgcatcc gcgcaaccgt catcacagcc
    71461 gctacgatct cgccacgctt tgtcaggtca atcctgaact caggcaattc ctcacgctta
    71521 cacccgccgg ggagcaaagc gtagactttg ccaatccgct ggcggtgaag gcgctcaata
    71581 aggcgttgct ggcccatttt tacgccgtag cgaactggga tatccccgac ggttttctct
    71641 gcccaccagt accgggccgg gcggattata ttcatcacct tgccgattta ctggcagaag
    71701 caagcggaac aattccagcg aatgccagca ttctggatat cggcgttggt gcgaactgta
    71761 tttatccgct gattggcgta catgaatatg gctggcgttt taccggtagt gaaaccagca
    71821 gccaggcgtt aagcagtgcg caggcgatta tcagttctaa tccggggctt aaccgcgcca
    71881 ttcgtctgcg tcggcaaaaa gagagtgggg cgatttttaa cggcatcatc cataaaaacg
    71941 agcaatacga cgcgaccttg tgtaacccgc cattccacga ttccgccgct gcggcacggg
    72001 caggtagtga gcgtaaacgc cgtaacctgg ggctgaacaa agacgatgca ctgaactttg
    72061 gcggccagca acaggagttg tggtgtgaag gcggtgaagt cacctttatc aaaaagatga
    72121 ttgaagagag caaaggcttc gcgaagcagg tgatgtggtt tacatcactg gtatctcgtg
    72181 gtgaaaactt accgccgttg tatcgtgccc tgacggacgt gggcgcggtg aaggtggtta
    72241 aaaaagagat ggcccagggg caaaagcaga gtcgctttat tgcctggacc tttatgaacg
    72301 acgagcagcg ccgccgtttt gtcaatcgcc agcgttaaag cgttggttcc cccggcggta
    72361 acggttcagc cggggtcgcg cccggagcag gcagcacctg ataagtctgc actggcgcgc
    72421 gaacgcccgc caggtcgaaa tgttttttca cctggctgtc gagggcaaag cgtaccgtcc
    72481 actgtttgag tggcagcgtg gtgaacgaaa cacgcagtgt aaacgcggta ttgcttaagc
    72541 cgacaatccc ggcaaaattc ggttcaccaa taatcagccc gcgaatttct tcgttttcca
    72601 ttaattccgc taccgcatct ttcagtgcct gattggcttt atcagcatct tcatggcgat
    72661 caacatcata atttgccacc accgaaccaa tgccgcggac aaagttagca aaggtggtta
    72721 tcgaagacca cggaatgatg tgatacgccc cggtatcctg tcgtacgccc acggagcgaa
    72781 tcgacatccg ttccactgtg ccggtcaacg gcccgatagt caccaaatct ccagtgttca
    72841 tgccgttttc aaactgaata aataccccgg tgataatatc tttcaccagc gtttgcgaac
    72901 caaacgagat agccagacct aatgccccgg cacctgccag caatggcgcg atattgacgc
    72961 cgatttccga caacacaatc atgatggtga tggtactgat aatcaccgcc agcgcgttac
    73021 gaaacagcgt aagcagggta cgcgtgcggg cgctgggtag cgggcggcca tgaatatccg
    73081 aagccagccg gttttcgatc aaactggcga gcaccgtcca gccaaccgcc gagaagaaaa
    73141 gaatgagtgc gatacggatc aggatatcta cggttttctg ccccgcgccg ttttgcagcc
    73201 agttccagaa atcgaacaat ccccatgcgc tcaacagcaa cattaccgcc acgcagactg
    73261 tcagaatacg cgccgttttc agcgccgccg acagccagcc attcaaccgt ttttgcagct
    73321 ccggatagtt acgctgagta tgtggcgaga gagtgatggt tttcgccagc cagcgggaaa
    73381 acataccgga aacaaacgct gcgataccaa taatcgccag gctgcgcacc gttgcaccca
    73441 tcataaattt caggctgttg cccggatcga acaacgaaaa gaaaaacagc acgataaaat
    73501 aggcgcttgc cagccagtgc cacaccagcg caaaggcgcg gataaacagg ctgaaaaagg
    73561 ccagcgaatg ctccgcgaag ttgagcaaat gctgggtaat ctctttttta ttacgaaaga
    73621 tcaggtacaa cgcccagacg gtcatgcaca gcataatgat gacgttcgcc agcgcaccta
    73681 tctgtacatt cacctgatta gagataatcg gcacggccac aatcaggcca taacctatca
    73741 aactgcttaa ccagctcagg cgacgactcc agtaacgggc gctctcgtcc tgaatcgtga
    73801 acgggcgcag ctccgccacg tttgggcaaa aaatcaggcg tagtacggct ttgaaaaatt
    73861 caatgagggc aaaggcgttg agaaacaaac tttgttggaa agcgatggtg cgactgcctg
    73921 cattcaggtt gtcgcttaat acctggccga caaataatgt cagggccagt aacagcaggt
    73981 cgataataaa cgccccgata atcatcgccg gaagctgcaa ccagttgctg cgctcacgat
    74041 ttttttgccg cgcccactga cccattttgc gatacagcgg cagtgcgcac aggcgaatca
    74101 gccagtaaaa accaaacact aataccgcta acattgaaaa atgggtcagc gcattgctga
    74161 aggtttgtgg attaaacggc ttatgcgggg agccggtgat attgcgataa agttgcccga
    74221 agcgggcgga aagggcttca ccataatggc ggctgacttc ggtgaccttt tgcagcacgg
    74281 tttgctcttc gaccagcgtc ggcggcacta tttttggtac cggttcagca gggggcgtag
    74341 cggcaacggt gcgcaactgg tcgatcaact ctttacgcga ggtgtcatta tccagcacat
    74401 ccgccagtgc gccataggcc gctttttttt gttcgatatc cggttccggg gccggttcag
    74461 tcgttgagtc cgttgtcgtt gtggttgtaa cgccgggtat ggataccgcg tgggcaggtg
    74521 cgcccagcag gcagaagagg atgaacagga tccaccgcat gactcctcca gtgagaaaat
    74581 agagcaaaaa gataagtata gatgctggag gaggggcgat tttaaatgag aggaatctgg
    74641 tgtgcctccc tttcgggtga aagggaggaa gggatattaa gcaggttgct gacaacgtgc
    74701 gggctttttt gccggatgcg gcgtgaacgc cttatccgtc ctacaagttc atgcaatttt
    74761 aataagttgc cagatatcct gtaggcctga taagcgtagc gcatcaggca atgtgtctta
    74821 ttaagagacg tgctgcaaaa attcctgcaa gcgctggctc ggcgggttct tgatcaacac
    74881 ctgcggattg ccatcttccg caatccggcc tttgtcgata aagatcagcc gcgaagctac
    74941 tttctcggca aaaccgattt cgtgggtcac gatcaccatc gtcatccctt cttcagccag
    75001 atcctgcata accttcagca cttcatggcg cagttccggg tcaagagcgg aagtcggttc
    75061 atcaaacagc atcattttcg gcttcaccgc cagcgcgcgg gcaatcgcca cacgctgctg
    75121 ttgaccacca gaaagttcgg aagggtagtg atgtgcacgt tctgccagac cgactttcgc
    75181 cagcagctca cgtgccagtt tttccgcctc ttctttgttc gcgccacgca cgcgtagcgg
    75241 gccaaacatg acgttttcca gcgctgtcag atgcgggaag aggtaaaact gctggaacac
    75301 catacctgct tcctggcgaa tcaggcgctc gtcaactttc ggatcgttaa ccttcaggcc
    75361 atcgacaatc agatcgccgg aggtgatttc ttccagtttg ttgatgcagc gcagcagggt
    75421 cgatttaccg gaaccggacg gcccgataat caccacgact tcgccctggg caatgttcaa
    75481 atcgatattg tgcagcacct gggttgggcc aaagtgcttg gagacgtttt taaattcaat
    75541 cacaggattt tcatccttct ttccagacga cgcagaataa agctcagcac cagggtaata
    75601 atcagataga acaccgccac ggcgctccag atctcaaggg cgcggaagtt accggcaata
    75661 atttcttgcc cctgacgggt cagttccgcc acgccgatca caataaacag cgaggtgtct
    75721 ttaatgctga tgatccactg gttacccagc ggcggcagca tacgacgcag tgccagcggt
    75781 aaaatgacgt agcgaatggt ttcccaacgt gaaagaccga gcgccagtcc tgcttcacga
    75841 aaacctttgt ggatagacag caccgcacca cgcgtgattt ccgcaatata cgcgccggag
    75901 ttgatcatga tggtgaccac cgccgcagta aatgggtcga tgcgtaagtc gttaaacgcc
    75961 atcggcaggg cgaaataaat aaacatcacc tggacgacga taggtgtgcc gcggatcact
    76021 tcaataaaga ccagcgcgac gtggttggct atccaacctc cgaaggtgcg tgcaaaacct
    76081 gccagcaatc cgattaccag accgcctgcc agaccgagga ccgaaatcca cagggtcatt
    76141 ttggcacctt caatcagaag cggaatggca ggccagatgg cactccagtc aaactgcata
    76201 tgttgttcct gttaccgtgg tgtaaataat caaattcagg gtaattaatg gccccggagc
    76261 gggtttgcgc ccctcaccct aatcctctcc ccatagggga gagggaactg ccagtgcgtt
    76321 ttacaggtgt agcgttatta tttcggttca gtaccgaacc attttttgta gatttcgttg
    76381 taagttccgt tctcgcgcag ggttttcaac gcgccgttga ctttgtcacg cagctcgtcg
    76441 ctacctttcg ggaacgcaat accgtattgc tgcgcttcca gagagtcacc taccgctttg
    76501 aactgaccgt taccggcggt tttgatgaag tacagaatgt ttggcgtatc gtgcagaacg
    76561 gcgtctgcgc ggttggtgcc cagttccata taggcgttat cgatgttcgg gaactgacgc
    76621 agatctttag ttttgatgtt tgctttcgcg taatcaacgg agccagtacc gctcttcaca
    76681 gcaaccactt tcccgtcgag atctttcacg cttttcacat cgttattgtt agctttcacc
    76741 atcactaaca ggccgctttt gtagtagccg tcagagaaat cgatcgcttt tttacgctcg
    76801 tcggtgatgg taatgcccgc cagcgccaga tcgacgtttt tggtttgcag tgccggaatg
    76861 atcccactga aatccatcgg cttcagttcg taatccagct tcagctcttt agcgatggca
    76921 gcccacagat caacgtcaaa gcccacatat ttatcgccct gtttaaattc aaacggaacg
    76981 aaggcggtat ccgtcgcgac aactaatttt ttatccgcgg catgagaaga aaccgcaaaa
    77041 gccagggtca gtgcagccag tgaaactttt aatacagact tcatagcatt tccttttttc
    77101 tatccacggg acgatcccct gcgtgacatt cacatatatg aaaaaatcgt gccagttttg
    77161 caactccttg atttttcgag atgcggcaaa aacgtgatgc acgatttata gggcaatacc
    77221 ctgaagatgc accattctgg ggcaccaatc tggtgcgcta aaattgtgca ctcaacacag
    77281 tgattattta gcgtaaaacc tgatgaaaaa acaatcttta tgtaacgatt gtgtgatgat
    77341 gtggatacaa aaaatttact taatcagctg gagatagcag atggatgcac taaataagtg
    77401 cgttgaggtg ggctgcaaaa caaaacggcc tcctgtcagg aagccgcttt tatcgggtac
    77461 taaagttctg caccatcagc gatggattta ttcgatgtta gactcgataa accacaggaa
    77521 tttatccagg tcgcgagacg cggcggtcag gatatctgcg gtgtcgtcat ctttcgcttc
    77581 gccaatcgct ttgcgtacgt cattagcgac gattgcgtaa cggtcagcca gttctttcag
    77641 gtgatcctga acgttgtgga tgtccagcgg gtaacttttc agcggggttt tgctgttgat
    77701 aacttgagtg gtccccagag ctacaccgcc cagctgcact gcacgttctg ccatggtatc
    77761 cagatgatcg atcagtgcgg tgcggaagcc atccagcatt tcatgtacgg caatgaagtt
    77821 agcgccgcgc atgttccagt gcgcttgttt ggtaatcaaa gaaagatcaa taaactggat
    77881 aacctggcga ttcagcaact ctactgttgc ttttttctcg ctgtcggaga catcgttgcg
    77941 ggtataaagc agattggtcg cttttgattt aactaattta gcggtactca taatttcata
    78001 tcctcttgat gttatgtccc agtaattaac gagactaagt atagcaccgg ctatgtgttc
    78061 cgctattctg gctgttccta tcacactaat agtggtaaca agcgtgaaaa acaaaactaa
    78121 taaagattca atgagttaga tatattgata agaacaattc ttatttatct gctcgccagg
    78181 aatt
//
LOCUS       DAPOAV010000008        77732 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.008, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000008 DAPOAV010000000
VERSION     DAPOAV010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 77732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 77732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..77732
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.008"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            156..1289
                     /gene="ompN"
                     /locus_tag="RN951_000678"
     CDS             156..1289
                     /gene="ompN"
                     /locus_tag="RN951_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpN"
                     /protein_id="HDX2525728.1"
                     /translation="MKSKVLALLIPALLAAGAAHAAEVYNKDGNKLDLYGKVDGLHYF
                     SDNSAKDGDQSYARLGFKGETQINDQLTGYGQWEYNIQANNTESSKNQSWTRLAFAGL
                     KFADYGSFDYGRNYGVMYDIEGWTDMLPEFGGDSYTNADNFMTGRANGVATYRNTDFF
                     GLVNGLNFAVQYQGNNEGASNGQEGTNNGRDVRHENGDGWGLSTTYDLGMGFSAGAAY
                     TSSDRTNDQVNHTAAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPFGDSDYAVAN
                     KTQNFEVTAQYQFDFGLRPAVSFLMSKGRDLHAAGGADNPAGVDDKDLVKYADIGATY
                     YFNKNMSTYVDYKINLLDEDDSFYAANGISTDDIVALGLVYQF"
     gene            1430..1864
                     /gene="uspF"
                     /locus_tag="RN951_000679"
     CDS             1430..1864
                     /gene="uspF"
                     /locus_tag="RN951_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415894.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspF"
                     /protein_id="HDX2525729.1"
                     /translation="MNRTILVPIDISDSELTQRVISHVEEEAKIDDAEVHFLTVIPSL
                     PYYASLGLAYSAELPAMDDLKAEAKSQLEEIIKKFKLPTDRVHVHVEEGSPKDRILEL
                     AKKIPAHMIIIASHRPDITTYLLGSNAAAVVRHAECSVLVVR"
     gene            2041..2976
                     /gene="ttcA"
                     /locus_tag="RN951_000680"
     CDS             2041..2976
                     /gene="ttcA"
                     /locus_tag="RN951_000680"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HDX2525730.1"
                     /translation="MSQNQEISKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMV
                     CLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHVLPEYLEKLGVEYKI
                     VEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFL
                     NMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIQRFADAKAFPIIPCNLCGSQPN
                     LQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVNGGD
                     LAFDREEIPLQPACWQPEEDENQLDELRLNVVEVK"
     gene            complement(3105..4478)
                     /gene="dbpA"
                     /locus_tag="RN951_000681"
     CDS             complement(3105..4478)
                     /gene="dbpA"
                     /locus_tag="RN951_000681"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DbpA"
                     /protein_id="HDX2525731.1"
                     /translation="MTAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVR
                     VQAKTGSGKTAAFGLGLLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLPNTK
                     ILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNTLVMDEADRMLD
                     MGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQRDPLAIEIDSTDALPPIEQ
                     QFYETSSKGKIPLLQRLLSLHQPSSCVVFCNTKKDCQAVCDALNEVGQSALSLHGDLE
                     QRDRDQTLVRFANGSARVLVATDVAARGLDIKSLELVVNFELAWDPEVHVHRIGRTAR
                     AGNSGLAISFCAPEEAQRANIISDMLQIKLNWQTPPANSSIATLEAEMATLCIDGGKK
                     AKMRPGDVLGALTGDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGKT
                     CRVRLLK"
     gene            complement(4956..5939)
                     /gene="zntB"
                     /locus_tag="RN951_000682"
     CDS             complement(4956..5939)
                     /gene="zntB"
                     /locus_tag="RN951_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZntB"
                     /protein_id="HDX2525732.1"
                     /translation="MEAIKGSDVNVPDAVFAWMLDGRGGVKPLENTDVIDEAHPCWLH
                     LNYVHHDSAQWLATTPLLPNNVRDALAGESTRPRVSRLGEGTLITLRCINGSTDERPD
                     QLVAMRVYMDGRLIVSTRQRKVLALDDVVSDLEEGTGPTDCGGWLVDVCDALTDHSSE
                     FIEQLHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPW
                     MSDDQRRRMQDIADRLGRGLDEIDACIARTGVMADEIAQVMQENLARRTYTMSLMAMV
                     FLPSTFLTGLFGVNLGGIPGGGWQFGFSIFCILLVVLIGGVALWLHRSKWL"
     gene            6194..7426
                     /gene="dgcM"
                     /locus_tag="RN951_000683"
     CDS             6194..7426
                     /gene="dgcM"
                     /locus_tag="RN951_000683"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415857.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcM"
                     /protein_id="HDX2525733.1"
                     /translation="MITHNFNTLDLLTSPVWIVSPFEEQLIYANSAAKLLMQDLTFSQ
                     LRTGPYSVSSQKELPKYLSDLQNQHDIIEILTVQRKEEETALSCRLVLRKLTETEPVI
                     IFEGIEAPATLGLKASRSANYQRKKQGFYARFFLTNSAPMLLIDPSRDGQIVDANLAA
                     LNFYGYNHETMCQKHTWEINMLGRRVMPIMHEISHLPGGHKPLNFVHKLADGSTRHVQ
                     TYAGPIEIYGDKLMLCIVHDITEQKRLEEQLEHAAHHDAMTGLLNRRQFYHITEPGQM
                     QHLAIAQDYSLLLIDTDRFKHINDLYGHSKGDEVLCALARTLESCARKGDLVFRWGGE
                     EFVLLLPRTPLDTALSLAETIRVSVAKVSISGLPRFTVSIGVAHHEGNESIDELFKRV
                     DDALYRAKNDGRNRVLAA"
     gene            complement(7447..8010)
                     /gene="smrA"
                     /locus_tag="RN951_000684"
     CDS             complement(7447..8010)
                     /gene="smrA"
                     /locus_tag="RN951_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA endonuclease SmrA"
                     /protein_id="HDX2525734.1"
                     /translation="MNLDDKSLFLDAMEDVQPLKRATDVHWHPTRNQRAPQRIDTLQL
                     DNFLTTGFLDIIPLSQPLEFRREGLQHGVLDKLRSGKYPQQASLNLLRQPVEECRKMV
                     FSFIQQALADGLRNVLIIHGKGRDDKSHANIVRSYVARWLTEFDDVQAYCTALPHHGG
                     SGACYVALRKTAQAKQENWERHAKRSR"
     gene            complement(8340..9248)
                     /locus_tag="RN951_000685"
     CDS             complement(8340..9248)
                     /locus_tag="RN951_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX2525735.1"
                     /translation="MAFQVKIHQIRAFVEVARQGSIRGASRMLNMSQPALSKSIQELE
                     EGLAAQLFFRRSKGVTLTDAGESFYQHASLILEELRAAQEDIRQRQGQLAGQINIGMG
                     ASISRSLMPAVISRFHQQHPQVKVRIMEGQLVSMINELRQGELDFTINTYYQGPYDHE
                     FTFEKLLEKQFAIFCRPGHPAIGARSIKQLLDYSWTMPTPHGSYYKQLSELLDDQAQT
                     PQVGVVCETFSACISLVAKSDFLSILPEEMGCDPLHGQGLVMLPVSEILPKAAYYLIQ
                     RRDSRQTPLTASLITQFRRECGYLQS"
     gene            9424..10734
                     /gene="abgA"
                     /locus_tag="RN951_000686"
     CDS             9424..10734
                     /gene="abgA"
                     /locus_tag="RN951_000686"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415854.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-aminobenzoyl-glutamate hydrolase subunit AbgA"
                     /protein_id="HDX2525736.1"
                     /translation="MESLNQFVNSLAPKLSHWRRDFHHYAESGWVEFRTATLVAEELH
                     QLGYSLALGREVVNESSRMGLPDEFTLQREFERARQQGALAQWIAAFEGGFTGIVATL
                     DTGRPGPVMAFRVDMDALDLSEEQDVSHRPYRDGFASCNAGMMHACGHDGHTAIGLGL
                     AHTLKQFESGLHGVIKLIFQPAEEGTRGARAMVDAGVVDDVDYFTAVHIGTGVPAGTV
                     VCGSDNFMATTKFDAHFTGTAAHAGAKPEDGHNALLAAAQATLALHAIAPHSEGASRV
                     NVGVMQAGSGRNVVPASALLKVETRGASDVINQYVFDRAQQAIQGAATMYGVGVETRL
                     MGAATASSPSPQWVAWLQSQAAQVAGVNQAIERVEAPAGSEDATLMMARVQQHQGQAS
                     YVVFGTQLAAGHHNEKFDFDEQVLAIAVETLARTALNFPWTRGI"
     gene            10734..12179
                     /gene="abgB"
                     /locus_tag="RN951_000687"
     CDS             10734..12179
                     /gene="abgB"
                     /locus_tag="RN951_000687"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-aminobenzoyl-glutamate hydrolase subunit AbgB"
                     /protein_id="HDX2525737.1"
                     /translation="MQEIYRFIDDAIEADRQRYTDIADQIWDHPETRFEEFWSAEHLA
                     SALESAGFTVTRNVGNIPNAFIASFGQGKPVIALLGEYDALAGLSQQAGCAQPTSVTP
                     GENGHGCGHNLLGTAAFAAAIAVKKWLEQYGQGGTVRFYGCPGEEGGSGKTFMVREGV
                     FDDVDAALTWHPEAFAGMFNTRTLANIQASWRFKGIAAHAANSPHLGRSALDAVTLMT
                     TGTNFLNEHIIEKARVHYAITNSGGISPNVVQAQAEVLYLIRAPEMTDVQHIYDRVAK
                     IAEGAALMTETTVECRFDKACSSYLPNRTLENAMYQALSHFGTPEWNSEELAFAKQIQ
                     ATLTSNDRQNSLNNIAATGGENGKVFALRHRETVLANEVAPYAATDNVLAASTDVGDV
                     SWKLPVAQCFSPCFAVGTPLHTWQLVSQGRTSIAHKGMLLAAKTMAATTVNLFLDSGL
                     LQECQQEHQQVTDTQPYHCPIPKNVTPSPLK"
     gene            12216..13742
                     /gene="abgT"
                     /locus_tag="RN951_000688"
     CDS             12216..13742
                     /gene="abgT"
                     /locus_tag="RN951_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415852.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-aminobenzoyl-glutamate transporter"
                     /protein_id="HDX2525738.1"
                     /translation="MSMSSIPSSSQSGKLYGWVERIGNKVPHPFLLFIYLIIVLMVTT
                     AILSAFGVSAKNPTDGTPVVVKNLLSVEGLHWFLPNVIKNFSGFAPLGAILALVLGAG
                     LAERVGLLPALMVKMASHVNARYASYMVLFIAFFSHISSDAALVIMPPMGALIFLAVG
                     RHPVAGLLAAIAGVGCGFTANLLIVTTDVLLSGISTEAAAAFNPQMHVSVIDNWYFMA
                     SSVVVLTIVGGLITDKIIEPRLGQWQGNSDEKLQTLTESQRFGLRIAGVVSLLFIAAI
                     ALMVIPQNGILRDPINHTVMPSPFIKGIVPLIILFFFVVSLAYGIATRTIRRQADLPH
                     LMIEPMKEMAGFIVMVFPLAQFVAMFNWSNMGKFIAVGLTDILESSGLSGIPAFVGLA
                     LLSSFLCMFIASGSAIWSILAPIFVPMFMLLGFHPAFAQILFRIADSSVLPLAPVSPF
                     VPLFLGFLQRYKPDAKLGTYYSLVLPYPLIFLVVWLLMLLAWYLVGLPIGPGIYPRLS
                     "
     gene            13753..14268
                     /gene="ogt"
                     /locus_tag="RN951_000689"
     CDS             13753..14268
                     /gene="ogt"
                     /locus_tag="RN951_000689"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDX2525739.1"
                     /translation="MLRLLEEKIATPLGPLWVICDEQFRLRAVEWEEYSERMVQLLDI
                     HYRKEGYERISATNPGGLSDKLREYFAGNLSIIDTLPTATGGTPFQREVWKTLRTIPC
                     GQVMHYGQLAEQLGRPGAARAVGAANGSNPISIVVPCHRVIGRNGTMTGYAGGVQRKE
                     WLLRHEGYLLL"
     gene            14463..15215
                     /gene="fnr"
                     /locus_tag="RN951_000690"
     CDS             14463..15215
                     /gene="fnr"
                     /locus_tag="RN951_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007849744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="HDX2525740.1"
                     /translation="MIPEKRIIRRIQSGGCAIHCQDCSISQLCIPFTLNEHELDQLDN
                     IIERKKPIQKGQTLFKAGDELKSLYAIRSGTIKSYTITEQGDEQITGFHLAGDLVGFD
                     AIGSGHHPSFAQALETSMVCEIPFETLDDLSGKMPNLRQQMMRLMSGEIKGDQDMILL
                     LSKKNAEERLAAFIYNLSRRFAQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRF
                     QKSGMLAVKGKYITIENNDALAQLAGHTRNVA"
     gene            15367..16317
                     /gene="uspE"
                     /locus_tag="RN951_000691"
     CDS             15367..16317
                     /gene="uspE"
                     /locus_tag="RN951_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspE"
                     /protein_id="HDX2525741.1"
                     /translation="MAMYQNMLVVIDPNQDDQPALRRAVYLHQRIGGKIKAFLPIYDF
                     SYEMTTLLSPDERTAMRQGVISQRTAWIHEQAKYYLNAGVPIEIKVVWHNRPFEAIIQ
                     EVISGGHDLVLKMAHQHDRLEAVIFTPTDWHLLRKCPSPVWMVKDQPWPEGGKALVAV
                     NLASEEPYHNALNEKLVKETIELAEQVNHTEVHLVGAYPVTPINIAIELPEFDPSVYN
                     DAIRGQHLLAMKALRQKFGINENMTHVEKGLPEEVIPDLAEHLQAGIVVLGTVGRTGI
                     SAAFLGNTAEQVIDHLRCDLLVIKPDQYQTPVELDDEEDD"
     gene            complement(16367..16624)
                     /locus_tag="RN951_000692"
     CDS             complement(16367..16624)
                     /locus_tag="RN951_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2534 family protein"
                     /protein_id="HDX2525742.1"
                     /translation="MIMAKLKSAKGKKFLFGLLAVFIIAASVVTRATIGGVIEQYNIP
                     LSEWTTSMYVIQSSMIFVYSLVFTVLLAIPLGIYFLGGEEQ"
     gene            16868..17899
                     /gene="ynaI"
                     /locus_tag="RN951_000693"
     CDS             16868..17899
                     /gene="ynaI"
                     /locus_tag="RN951_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low conductance mechanosensitive channel YnaI"
                     /protein_id="HDX2525743.1"
                     /translation="MIAELFTNNALNLVIIFGSCAALILMSFWFRRGNRKRKGFLFHA
                     VQFLIYTIIISAVGSIINYVIENYKLKFITPGVIDFICTSLIAVILTIKLFLLINQFE
                     KQQIKKGRDITSARIMSRIIKITIIVVLVLLYGEHFGMSLSGLLTFGGIGGLAVGMAG
                     KDILSNFFSGIMLYFDRPFSIGDWIRSPDRNIEGTVAEIGWRITKITTFDNRPLYVPN
                     SLFSSISVENPGRMTNRRITTTIGLRYEDAAKVGVIVEAVREMLKNHPAIDQRQTLLV
                     YFNQFADSSLNIMVYCFTKTTVWAEWLAAQQDVYLKIIDIVQSHGADFAFPSQTLYMD
                     NITPPEQGR"
     gene            complement(17950..19563)
                     /gene="mppA"
                     /locus_tag="RN951_000694"
     CDS             complement(17950..19563)
                     /gene="mppA"
                     /locus_tag="RN951_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415845.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide ABC transporter
                     substrate-binding protein MppA"
                     /protein_id="HDX2525744.1"
                     /translation="MKHSVSVTCCALLVSSISLSYAAEVPSGTVLAEKQELVRHIKDE
                     PASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIVPGVATQWKSNDNRIWTFTLRDNA
                     KWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGINNAQAIIDGKATPDQLGVTA
                     VDAHTLKIQLDKPLPWFVNLTANFAFFPVQKANVESGKEWTKPGNLIGNGAYVLKERV
                     VNEKLVVVPNTHYWDNAKTVLQKVTFLPINQESAATKRYLAGDIDITESFPKNMYQKL
                     LKDIPGQVYTPPQLGTYYYAFNTQKGPTADQRVRLALSMTIDRRLMTEKVLGTGEKPA
                     WHFTPDVTAGFTPEPSPFEQMSQEELNAQAKTLLSAAGYGPQKPLKLTLLYNTSENHQ
                     KIAIAVASMWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLTLL
                     TSTHSGNISRFNNPAYDKVLAQASTENTVKARNADYNAAEKILMEQAPIAPIYQYTNG
                     RLIKPWLKGYPINNPEDVAYSRTMYIVKH"
     gene            complement(19900..20799)
                     /gene="pgrR"
                     /locus_tag="RN951_000695"
     CDS             complement(19900..20799)
                     /gene="pgrR"
                     /locus_tag="RN951_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator PgrR"
                     /protein_id="HDX2525745.1"
                     /translation="MKREEIADLMAFVVVAEERSFTRAAARLSMAQSALSQIVRRIEE
                     RLGLRLLTRTTRSVVPTEAGEHLLSVLGPMLHDIDSAMASLSDLQNRPSGTIRITTVE
                     HAAKTILLPAMRTFLKSHPEIDIQLTIDYGLTDVVSERFDAGVRLGGEMDKDMIAIRI
                     GPDIPMAIVGSPDYFSRRSVPTSVSQLIDHQAINLYLPTSGTANRWRLIRGGREVRVR
                     MEGQLLLNTIDLIIDAAIDGHGLAYLPYDQVERAIKEKKLIRVLDKFTPDLPGYHLYY
                     PHRRHAGSAFSLFIDRLKYKGAV"
     gene            20937..21857
                     /locus_tag="RN951_000696"
     CDS             20937..21857
                     /locus_tag="RN951_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415843.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDX2525746.1"
                     /translation="MINNKVSFTNSNNPTISLSAVIYFPPKFDETRQYQAIVLSHPGG
                     GVKEQTAGTYAKKLAEKGFVTIAYDASYQGESGGEPRQLENPYIRTEDISAVIDYLTT
                     LSYVDNTRIGAMGICAGAGYTANAAIQDRRIKAIGTVSAVNIGSIFRNGWENNVKSID
                     ALPYVEAGSNARTSDISSGEYAIMPLAPMKESDAPNEELRQAWEYYHTPRAQYPTAPG
                     YATLRSLNQIITYDAYHMAEVYLTQPTQIVAGSQAGSKWMSDDLYDRASSQDKRYHIV
                     EGANHMDLYDGKAYVAEAISVLAPFFEETL"
     gene            21928..22065
                     /locus_tag="RN951_000697"
                     /pseudo
     CDS             21928..22065
                     /locus_tag="RN951_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707232.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dehydratase"
     gene            22192..22920
                     /gene="mpaA"
                     /locus_tag="RN951_000698"
     CDS             22192..22920
                     /gene="mpaA"
                     /locus_tag="RN951_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415842.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide amidase MpaA"
                     /protein_id="HDX2525747.1"
                     /translation="MTVTRPRAERGAFPPGTEHYGRSLLGAPLIWFPAPAASRESGLI
                     LAGTHGDENSSVVTLSCALRTLTPSLRRHHVVLCVNPDGCQLGLRANANGVDLNRNFP
                     AANWKEGETVYRWNSAAEERDVVLLTGDKPGSEPETQALCQLIHRIQPAWVVSFHDPL
                     ACIEDPRHSELGEWLAQAFELPLVTSVGYETPGSFGSWCEDLNLHCITAEFPPISSDE
                     ASEKYLFAMANLLRWHPKDAIRPS"
     gene            complement(22895..23860)
                     /gene="ycjG"
                     /locus_tag="RN951_000699"
     CDS             complement(22895..23860)
                     /gene="ycjG"
                     /locus_tag="RN951_000699"
                     /EC_number="5.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415841.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-Ala-D/L-Glu epimerase"
                     /protein_id="HDX2525748.1"
                     /translation="MRTVKVFEEAWPLHTPFVIARGSRSEARVVVVELEEEGIKGTGE
                     CTPYPRYGESDASVMAQIMSVVPQLEKGLTREELQKILPAGAARNALDCALWDLAARR
                     QQQSLADLIGITLPETVITAQTVVIGTPDQMANSASTLWQAGAKLLKVKLDNHLISER
                     MVAIRTAVPDATLIVDANESWRAEGLAARCQLLADLGVAMLEQPLPAQDDAALENFIH
                     PLPICADESCHTRSNLKALKGRYEMVNIKLDKTGGLTEALALATEARAQGFSLMLGCM
                     LCTSRAISAALPLVPQVSFADLDGPTWLAVDVEPALQFTTGELHL"
     gene            23979..24485
                     /gene="tpx"
                     /locus_tag="RN951_000700"
     CDS             23979..24485
                     /gene="tpx"
                     /locus_tag="RN951_000700"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HDX2525749.1"
                     /translation="MSQTVHFQGNPVTVANSIPQAGSKAQTFTLVAKDLSDVTLGQFA
                     GKRKVLNIFPSIDTGVCAASVRKFNQLATEIDNTVVLCISADLPFAQSRFCGAEGLNN
                     VITLSTFRNAEFLQAYGVAIADGPLKGLAARAVVVIDENDNVIFSQLVDEITTEPDYE
                     AALAVLKA"
     gene            complement(24529..26070)
                     /gene="tyrR"
                     /locus_tag="RN951_000701"
     CDS             complement(24529..26070)
                     /gene="tyrR"
                     /locus_tag="RN951_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TyrR"
                     /protein_id="HDX2525750.1"
                     /translation="MRLEVFCEDRLGLTRELLDLLVLRGIDLRGIEIDPIGRIYLNFA
                     ELEFESFSSLMAEIRRIAGVTDVRTVPWMPSEREHLALSALLEALPEPVLSVDMKSKV
                     DMANPASCQLFGQKLDRLRNHTAAQLINGFNFLRWLESEPQDSHNEHVVINGQNFLME
                     ITPVYLQDENDQHVLTGAVVMLRSTIRMGRQLQNVAAQDVSAFSQIVAVSPKMKHVVE
                     QAQKLAMLSAPLLITGDTGTGKDLFAYACHQASPRAGKPYLALNCASIPEDAVESELF
                     GHAPEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEVHVDVR
                     VICATQKNLVELVQKGMFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQ
                     GVPRPKLAADLNTVLTRYAWPGNVRQLKNAIYRALTQLDGYELRPQDILLPDYDAATV
                     AVGEDAMEGSLDEITSRFERSVLTQLYRNYPSTRKLAKRLGVSHTAIANKLREYGLSQ
                     KKNEE"
     gene            complement(26218..27279)
                     /locus_tag="RN951_000702"
     CDS             complement(26218..27279)
                     /locus_tag="RN951_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01620 family protein"
                     /protein_id="HDX2525751.1"
                     /translation="MTEPLKPRIDFDGPLEVDQNPKFRAQQTFDENQAQNFAPATLDE
                     AQEEEGQVEAVMDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVAL
                     GGCAAGALIIGAGVGSVVTEWRRLWRLRQRAHERDEARDLLHSHGTGKGRAFCEKLAQ
                     QAGIDQSHPALQRWYASIHETQNDREVVSLYAHLVQPVLDAQARREISRSAAESTLMI
                     AVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFKLVLLNIAFAGASELVR
                     EVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWIDDDKPRLGDFRR
                     QLIGQVKETLQKGKTPSEK"
     gene            complement(27276..28673)
                     /locus_tag="RN951_000703"
     CDS             complement(27276..28673)
                     /locus_tag="RN951_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcjX family protein"
                     /protein_id="HDX2525752.1"
                     /translation="MKRLKNELNALVNRGVDRHLRLAVTGLSRSGKTAFITAMVNQLL
                     NIHAGARLPLLSAVREERLLGVKRIPQRDFGIPRFTYDEGLAQLYGDPPAWPTPTRGV
                     SEIRLALRFKSNDSLLRHFKDTSTLYLEIVDYPGEWLLDLPMLAQDYLSWSRQMTGLL
                     NGQRGEWSAKWRMMSEGLDPLAPADENRLADIAAAWTDYLHHCKEQGLHFIQPGRFVL
                     PGDMAGAPALQFFPWPDVDTWGESKLAQADKHTNAGMLRERFNYYCEKVVKGFYKNHF
                     LRFDRQIVLVDCLQPLNSGPQAFNDMRLALTQLMQSFHYGQRTLFRRLFSPVIDKLLF
                     AATKADHVTIDQHANMVSLLQQLIQDAWQNAAFEGISMDCLGLASVQATTSGIIDVNG
                     EKIPALRGNRLSDGAPLTVYPGEVPARLPGQAFWDKQGFQFEAFRPQVMDVDKPLPHI
                     RLDAALEFLIGDKLR"
     gene            28829..29827
                     /locus_tag="RN951_000704"
     CDS             28829..29827
                     /locus_tag="RN951_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDX2525753.1"
                     /translation="MSPTIYDIARVAGVSKSTVSRVLNKQTNISPEAREKVLRAIEEL
                     QYQPNKLARALTSSGFDAIMVISTRSTKTTAGNPFFSEVLHAITAKAEEEGFDVILQT
                     SHNPAEDLQKCESKIKQKMIKGIIMLSSPADESFFAQLDKYDIPVVVIGKVEGQYAHV
                     YSVDTDNFGDSIALTDALIESGHQNIACLHAPLDVHVSVDRVNGYKQSLAAHNIAVRD
                     EWIVDGGYTHETALKAARQLLSQSPLPEAVFATDSLKLMSIYRAAAEKKIAIPQQLAV
                     VGYSNETLSFILTPAPGGIDVPTQELGQQSCELLFRLISGKPSPQNITVATHMTLK"
     gene            complement(29938..30843)
                     /gene="ompG"
                     /locus_tag="RN951_000705"
     CDS             complement(29938..30843)
                     /gene="ompG"
                     /locus_tag="RN951_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monomeric porin OmpG"
                     /protein_id="HDX2525754.1"
                     /translation="MKKLLPCTALVMCAGMACAQAEERNDWHFNIGAMYEIENVEGYG
                     EDMDGLAEPSVYFNAANGPWRIALAYYQEGPVDYSAGKRGTWFDRPELEVHYQFLEND
                     DFSFGLTGGFRNYGYHYVDEPGKDTANMQRWKIAPDWDVKLTDDLRFNGWLSMYKFAN
                     DLNTTGYADTRVETETGLQYTFNETVALRVNYYLERGFNMDDSRNNGEFSTQEIRAYL
                     PLTLGNHSVTPYTRIGLDRWSNWDWQDDIEREGHDFNRVGLFYGYDFQNGLSVSLEYA
                     FEWQDHDEGDSDKFHYAGVGVNYSF"
     gene            complement(30888..31970)
                     /locus_tag="RN951_000706"
     CDS             complement(30888..31970)
                     /locus_tag="RN951_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX2525755.1"
                     /translation="MAQLSLQHIQKIYDNQVHVVKDFNLEIADKEFIVFVGPSGCGKS
                     TTLRMIAGLEEISGGDLLIDGKRMNDVPAKARNIAMVFQNYALYPHMTVYDNMAFGLK
                     MQKIAKEVIDERVNWAAQILGLREYLKRKPGALSGGQRQRVALGRAIVREAGVFLMDE
                     PLSNLDAKLRVQMRAEISKLHQKLNTTMIYVTHDQTEAMTMATRIVIMKDGIVQQVGA
                     PKTVYNQPANMFVSGFIGSPAMNFIRGTIDGDKFVTETLKLTIPEEKLAVLKTQESLH
                     KPIVMGIRPEDIHPDAQEENNISAKISVAELTGAEFMLYTTVGGHELVVRAGALNDYH
                     AGENITIHFDMTKCHFFDAETEIAIR"
     gene            complement(31984..32643)
                     /gene="pgmB"
                     /locus_tag="RN951_000707"
     CDS             complement(31984..32643)
                     /gene="pgmB"
                     /locus_tag="RN951_000707"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDX2525756.1"
                     /translation="MKLQGVIFDLDGVITDTAHLHFQAWQQIAAEIGISIDAQFNESL
                     KGISRDESLRRILQHGGKEGDFNSQERAQLAYRKNLLYVHSLRELTVNAVLPGIRSLL
                     ADLRAQQISVGLASVSLNAPTILAALELREFFTFCADASQLKNSKPDPEIFLAACAGL
                     GVPPQACIGIEDAQAGIDAINASGMRSVGIGAGLTGAQLLLPSTESLTWPRLSAFWQN
                     V"
     gene            complement(32640..34907)
                     /gene="ycjT"
                     /locus_tag="RN951_000708"
     CDS             complement(32640..34907)
                     /gene="ycjT"
                     /locus_tag="RN951_000708"
                     /EC_number="2.4.1.230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kojibiose phosphorylase"
                     /protein_id="HDX2525757.1"
                     /translation="MTRPVTLSEPHFSQHTLNKYASLMAQGNGYLGLRASHEEDYTRQ
                     TRGMYLAGLYHRAGKGEINELVNLPDVVGMEIAINGEVFSLSHEAWQRELDFASGELR
                     RNVVWRTSNGSGYTIASRRFVSADQLPLIALEITITPLDADASVLISTGIDATQTNHG
                     RQHLDETQVRVFGQHLMQGSYTTQDGRSDVAISCCCKVSGDVQQCYTAKERRLLQHTS
                     AQLHAGETMTLQKLVWIDWRDDRQAALDEWGSASLRQLEMCAQQSYDQLLAASTENWR
                     QWWQKRRITVNGGEAHDQQALDYALYHLRIMTPAHDERSSIAAKGLTGEGYKGHVFWD
                     TEVFLLPFHLFSDPTVARSLLRYRWHNLPGAQEKARRNGWQGALFPWESARSGEEETP
                     EFAAINIRTGLRQKVASAQAEHHLVADIAWAVIQYWQTTGDESFIAHEGMALLLETAK
                     FWISRAVRVNDRLEIHDVIGPDEYTEHVNNNAYTSYMARYNVQQALNIARQFGCSDDA
                     FIHRAEMFLKELWMPEIQPDGVLPQDDSFMAKPAINLAKYKAAAGKQTILLDYSRAEV
                     NEMQILKQADVVMLNYMLPEQFSAASCLANLQFYEPRTIHDSSLSKAIHGIVAARCGL
                     LTQSYQFWREGTEIDLGADPHSCDDGIHAAATGAIWLGAIQGFAGVSVRDGELHLNPA
                     LPEQWQQLSFPLFWQGCELQVTLDAQRIAIRTSAPVSLRLNGQLITVAEESVFCLGDF
                     ILPFNGTATKHQEDE"
     gene            complement(34904..35959)
                     /locus_tag="RN951_000709"
     CDS             complement(34904..35959)
                     /locus_tag="RN951_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDX2525758.1"
                     /translation="MKSAMTSSPLRVAIIGAGQVADKVHASYYCTRNDLELVAVCDSR
                     LSQAQALAEKYGNASVWDDPQAMLLAVKPDVVSVCSPNRFHYEHTLMALEAGCHVMCE
                     KPPAMTPEQAREMCDTARKLGKVLAYDFHHRFALDTQQLREQVTNGVLGEIYVTTARA
                     LRRCGVPGWGVFTNKELQGGGPLIDIGIHMLDAAMYVLGFPAVKSVNAHSFQKIGTQK
                     SCGQFGEWDPATYSVEDSLFGTIEFHNGGILWLETSFALNIREQSIMNVSFCGDKAGA
                     TLFPAHIYTDNNGELMTLMQREMADDNRHLRSMEAFINHVQGKPVMIADAEQGYIIQQ
                     LVAALYQSAETGTRVEL"
     gene            complement(35969..36757)
                     /locus_tag="RN951_000710"
     CDS             complement(35969..36757)
                     /locus_tag="RN951_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415830.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDX2525759.1"
                     /translation="MKIGTQNQAFFPENILEKFRYIKEMGFDGFEIDGKLLVNNIEEV
                     KAAIKETGLPVTTACGGYDGWIGDFIEERRLNGLKQIERILEALAEVGGKGIVVPAAW
                     GMFTFRLPPMTSPRSLDGDRKMVSDSLRVLEQVAARTGTVVYLEPLNRYQDHMINTLA
                     DARRYIVENDLKHVQIIGDFYHMNIEEDNLAQALHDNRDLLGHVHIADNHRYQPGSGT
                     LDFHALFEQLRADNYQGYVVYEGRIRAEDPAQAYRDSLAWLRTC"
     gene            complement(36776..37828)
                     /locus_tag="RN951_000711"
     CDS             complement(36776..37828)
                     /locus_tag="RN951_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HDX2525760.1"
                     /translation="MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVD
                     FRAASPFIDEDFNGEWQMFTPRPADAPRGIEFGKFQLGNMVVGDIIECGSDVTDYAVG
                     DSVCGYGPLSETVIINAVNNYKLRKMPQGSSWKNAVCYDPAQFAMSGVRDANVRVGDF
                     VVVVGLGAIGQIAIQLAKRAGASVVIGVDPIAHRCDIARRHGADFCLNPIGTDVGKEI
                     KTLTGKQGADVIIETSGYADALQSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNN
                     AKIVFSRACSEPNPDYPRWSRKRIEETCWELLMNGYLNCEDLIDPVVTFANSPESYMQ
                     YVDQHPEQSIKMGVTF"
     gene            complement(37859..38701)
                     /locus_tag="RN951_000712"
     CDS             complement(37859..38701)
                     /locus_tag="RN951_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDX2525761.1"
                     /translation="MATNKRTLSRIGFYCGLALFLIITLFPFFVMLMTSFKGAKEAIS
                     LHPTLLPQQWTLEHYVDIFNPMIFPFVDYFRNSLVVSVVSSVVAVFLGILGAYALSRL
                     RFKGRMTINASFYTVYMFSGILLVVPLFKIITALGIYDTEMALIITMVTQTLPTAVFM
                     LKSYFDTIPDEIEEAAMMDGLNRLQIIFRITVPLAMSGLISVFVYCFMVAWNDYLFAS
                     IFLSSASNFTLPVGLNALFSTPDYIWGRMMAASLVTALPVVIMYALSERFIKSGLTAG
                     GVKG"
     gene            complement(38688..39569)
                     /locus_tag="RN951_000713"
     CDS             complement(38688..39569)
                     /locus_tag="RN951_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDX2525762.1"
                     /translation="MNRLFSGRSDMPFALLLLAPSLLLLGGLVAWPMVSNIEISFLRL
                     PLNPNIESTFVGVSNYVRILSDPGFWHSLWMTVWYTALVVAGSTVLGLAVAMFFNREF
                     RLRKTARSLVILSYVTPSISLVFAWKYMFNNGYGIVNYLGVDLLHLYEQAPLWFDNPG
                     SSFVLVVLFAIWRYFPYAFISFLAILQTIDKSLYEAAEMDGANAWQRFRIVTLPAIMP
                     VLATVVTLRTIWMFYMFADVYLLTTKVDILGVYLYKTAFAFNDLGKAAAISVVLFIII
                     FAVILLTRKRVNLNGNK"
     gene            complement(39590..40882)
                     /locus_tag="RN951_000714"
     CDS             complement(39590..40882)
                     /locus_tag="RN951_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDX2525763.1"
                     /translation="MIKSKIVLLSALVSCALISGCKEENKTNVSIEFMHSSVEQERQA
                     VISKLIARFEKENPGITVKQVPVEEDAYNTKVITLSRSGSLPEVIETSHDYAKVMDKE
                     QLIDRKAVATVISNVGEGAFYDGVLRIVRTEDGSAWTGVPVSAWIGGIWYRKDVLAKA
                     GLEEPKNWQQLLDVAQKLNDPANKKYGIALPTAESVLTEQSFSQFALSNQANVFNAEG
                     KITLDTPEMMQALTYYRDLAANTMPGSNDIMEVKDAFMNGTAPMAIYSTYILPAVIKE
                     GDPKNVGFVVPTEKNSAVYGMLTSLTITAGQKTEETEAAEKFVTFMEQADNIADWVMM
                     SPGAALPVNKAVVTTATWKDNDVIKALGELPNQLIGELPNIQVFGAVGDKNFTRMGDV
                     TGSGVVSSMVHNVTVGKADLSTTLQASQKKLDELIEQH"
     gene            complement(40896..42575)
                     /gene="ycjM"
                     /locus_tag="RN951_000715"
     CDS             complement(40896..42575)
                     /gene="ycjM"
                     /locus_tag="RN951_000715"
                     /EC_number="2.4.1.352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415825.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosylglycerate phosphorylase"
                     /protein_id="HDX2525764.1"
                     /translation="MKQKITDYLDEIYGGTFTATHLQKLVTRLESAKRLITQRRKKHW
                     DESDVVLITYADQFHSNDLKPLPTFNQFYHQWLQSIFSHVHLLPFYPWSSDDGFSVID
                     YHQVASEAGEWQDIQQLGECSHLMFDFVCNHMSAKSEWFKNYLQQHPGFEDFFIAVDP
                     QTDLSAVTRPRALPLLTPFQMRDHSTRHLWTTFSDDQIDLNYRSPEVLLAMVDVLLCY
                     LAKGAEYVRLDAVGFMWKEPGTSCIHLEKTHLIIKLLRSIIDNVAPGTVIITETNVPH
                     KDNIAYFGAGDDEAHMVYQFSLPPLVLHAVQKQNVEALCAWAQNLTLPSSNTTWFNFL
                     ASHDGIGLNPLRGLLPESEILELVEALQQEGALVNWKNNPDGTRSPYEINVTYMDALS
                     RRESSDEERCARFILAHAILLSFPGVPAIYIQSILGSRNDYAGVEKLGYNRAINRKKY
                     HSKEITRELNDEATLRHAVYHELSRLITLRRSHNEFHPDNNFTIDTINSSVMRIQRSN
                     ADGNCLTGLFNVSKNIQHVNITNLHGRDLISEVDILGNEITLRPWQVMWIK"
     gene            complement(42788..43102)
                     /gene="pspE"
                     /locus_tag="RN951_000716"
     CDS             complement(42788..43102)
                     /gene="pspE"
                     /locus_tag="RN951_000716"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase PspE"
                     /protein_id="HDX2525765.1"
                     /translation="MFKKGLLALALVFSLPVFAAEHWIDVRVPEQYQQEHVQGAINIP
                     LKEVKERIATAVPDKNDTVKVYCNAGRQSGQAKEILSEMGYTHVENAGGLKDIAMPKV
                     KG"
     gene            complement(43177..43398)
                     /gene="pspD"
                     /locus_tag="RN951_000717"
     CDS             complement(43177..43398)
                     /gene="pspD"
                     /locus_tag="RN951_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspD"
                     /protein_id="HDX2525766.1"
                     /translation="MNTRWQQAGQKVKPGFKLAGKLVLLTALRYGPAGVAGWAIKSVA
                     RRPLKMLLAVALEPLLSRAANKLAQRYKR"
     gene            complement(43407..43766)
                     /gene="pspC"
                     /locus_tag="RN951_000718"
     CDS             complement(43407..43766)
                     /gene="pspC"
                     /locus_tag="RN951_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspC"
                     /protein_id="HDX2525767.1"
                     /translation="MAGINLNKKLWRIPQQGMVRGVCAGIANYFDVPVKLVRILVVLS
                     IFFGLALFTLVAYIILSFALDPMPDNMAFGEQLPSSSELLDEVDRELAASETRLREME
                     RYVTSDTFTLRSRFRQL"
     gene            complement(43766..43990)
                     /gene="pspB"
                     /locus_tag="RN951_000719"
     CDS             complement(43766..43990)
                     /gene="pspB"
                     /locus_tag="RN951_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspB"
                     /protein_id="HDX2525768.1"
                     /translation="MSALFLAIPLTIFVLFVLPIWLWLHYSNRSGRSELSQSEQQRLA
                     QLADEAKRMRERIQALESILDAEHPNWRDR"
     gene            complement(44044..44712)
                     /gene="pspA"
                     /locus_tag="RN951_000720"
     CDS             complement(44044..44712)
                     /gene="pspA"
                     /locus_tag="RN951_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspA"
                     /protein_id="HDX2525769.1"
                     /translation="MGIFSRFADIVNANINALLEKAEDPQKLVRLMIQEMEDTLVEVR
                     STSARALAEKKQLTRRIEQASAREVEWQEKAELALLKEREDLARAALIEKQKLTDLIK
                     SLEHEVTLVDDTLARMKKEIGELENKLSETRARQQALMLRHQAANSSRDVRRQLDSGK
                     LDEAMARFESFERRIDQMEVEAESHSFGKQKSLDDQFAELKADDAISEQLAQLKAKMK
                     QDNQ"
     gene            44879..45856
                     /gene="pspF"
                     /locus_tag="RN951_000721"
     CDS             44879..45856
                     /gene="pspF"
                     /locus_tag="RN951_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415819.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein operon transcriptional
                     activator"
                     /protein_id="HDX2525770.1"
                     /translation="MAEYKDNLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKEL
                     IASRLHYLSSRWQGPFISLNCAALNENLLDSELFGHEAGAFTGAQKRHPGRFERADGG
                     TLFLDELATAPMMVQEKLLRVIEYGELERVGGSQPLQVNVRLVCATNADLPAMVNEGT
                     FRADLLDRLAFDVVQLPPLRERESDIMLMAEYFAIQMCREIKLPLFPGFTERARETLL
                     NYRWPGNIRELKNVVERSVYRHGTSDYPLDDIIIDPFKRRPPEDAIAVSETTSLPTLP
                     LDLREFQMQQEKELLQLSLQQGKYNQKRAAELLGLTYHQFRALLKKHQI"
     gene            complement(45976..47241)
                     /gene="puuE"
                     /locus_tag="RN951_000722"
     CDS             complement(45976..47241)
                     /gene="puuE"
                     /locus_tag="RN951_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-aminobutyrate transaminase"
                     /protein_id="HDX2525771.1"
                     /translation="MSNNEFHQRRLSATPRGVGVMCNFFAQSAENATLKDVEGNEYID
                     FAAGIAVLNTGHRHPDLVAAVEQQLQQFTHTAYQIVPYESYVTLAEKINALAPVSGQA
                     KTAFFTTGAEAVENAVKIARAHTGRPGVIAFSGGFHGRTYMTMALTGKVAPYKIGFGP
                     FPGSVYHVPYPSDLHGISTQDSLDAIERLFKSDIEAKQVAAIIFEPVQGEGGFNVAPK
                     ELVAAIRRLCDEHGIVMIADEVQSGFARTGKLFAMDHYADKPDLMTMAKSLAGGMPLS
                     GVVGNANIMDAPAPGGLGGTYAGNPLAVAAAHAVLNIIDKESLCERANQLGQRLKNTL
                     IDAKESVPAIAAVRGLGSMIAVEFNDPQTGEPSAAIAQKIQQRALAQGLLLLTCGAYG
                     NVIRFLYPLTIPDAQFDAAMKILQDALSD"
     gene            complement(47279..48559)
                     /gene="puuB"
                     /locus_tag="RN951_000723"
     CDS             complement(47279..48559)
                     /gene="puuB"
                     /locus_tag="RN951_000723"
                     /EC_number="1.4.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylputrescine oxidase"
                     /protein_id="HDX2525772.1"
                     /translation="MTEHTSSYYAASANKYAPFDTLNESITCDVCVVGGGYTGLSSAL
                     HLAEAGFDVVVLEASRIGFGASGRNGGQLVNSYSRDIDVIEKSYGMDTARMLGSMMFE
                     GGEIIRERIKRYQIDCDYRPGGLFVAMNDKQLATLEEQKENWERYGNKQLELLDANAI
                     RREVASDRYTGALLDHSGGHIHPLNLAIGEADAIRLNGGRVYELSAVTQIQHTTPAVV
                     RTAKGQVTAKYVIVAGNAYLGDKVEPELAKRSMPCGTQVITTERLSEDLARSLIPKNY
                     CVEDCNYLLDYYRLTADNRLLYGGGVVYGARDPDDVERLVVPKLLKTFPQLKGVKIDY
                     RWTGNFLLTLSRMPQFGRLDTNIYYMQGYSGHGVTCTHLAGRLIAELLRGDAERFDAF
                     ANLPHYPFPGGRTLRVPFTAMGAAYYSLRDRLGV"
     gene            complement(48561..50048)
                     /gene="puuC"
                     /locus_tag="RN951_000724"
     CDS             complement(48561..50048)
                     /gene="puuC"
                     /locus_tag="RN951_000724"
                     /EC_number="1.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase PuuC"
                     /protein_id="HDX2525773.1"
                     /translation="MNFHHLAYWQDKALSLAIENRLFINGEYTAAAENETFETVDPVT
                     QAPLAKIARGKSVDIDRAMSAARGVFERGDWSLSSPAKRKAVLNKLADLMEAHAEELA
                     LLETLDTGKPIRHSLRDDIPGAARAIRWYAEAIDKVYGEVATTSSHELAMIVREPVGV
                     IAAIVPWNFPLLLTCWKLGPALAAGNSVILKPSEKSPLSAIRLAGLAKEAGLPDGVLN
                     VVTGFGHEAGQALSRHNDIDAIAFTGSTRTGKQLLKDAGDSNMKRVWLEAGGKSANIV
                     FADCPDLQQAASATAAGIFYNQGQVCIAGTRLLLEESIADEFLALLKQQAQNWQPGHP
                     LDPATTMGTLIDCAHADSVHSFIREGESKGQLLLDGRNAGLAAAIGPTIFVDVDPNAS
                     LSREEIFGPVLVVTRFTSEEQALQLANDSQYGLGAAVWTRDLSRAHRMSRRLKAGSVF
                     VNNYNDGDMTVPFGGYKQSGNGRDKSLHALEKFTELKTIWISLEA"
     gene            complement(50323..50880)
                     /gene="puuR"
                     /locus_tag="RN951_000725"
     CDS             complement(50323..50880)
                     /gene="puuR"
                     /locus_tag="RN951_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator PuuR"
                     /protein_id="HDX2525774.1"
                     /translation="MSDEGLAPGKRLSEIRQQQGLSQRRAAELSGLTHSAISTIEQDK
                     VSPAISTLQKLLKVYGLSLSEFFSEPEKPDEPQVVINQDDLIEMGSQGVSMKLVHNGN
                     PNRTLAMIFETYQPGTTTGERIKHQGEEIGTVLEGEIVLTINGQDYHLVAGQSYAINT
                     GIPHSFSNTSAGICRIISAHTPTTF"
     gene            complement(50907..51671)
                     /gene="puuD"
                     /locus_tag="RN951_000726"
     CDS             complement(50907..51671)
                     /gene="puuD"
                     /locus_tag="RN951_000726"
                     /EC_number="3.5.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415814.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase"
                     /protein_id="HDX2525775.1"
                     /translation="MENIMNNPVIGVVMCRNRLKGHATQTLQEKYLNAIIHAGGLPIA
                     LPHALAEPSLLEQLLPKLDGIYLPGSPSNVQPHLYGENGDEPDADPGRDLLSMAIINA
                     ALERRIPIFAICRGLQELVVATGGSLHRKLCEQPELLEHREDPELPVEQQYAPSHEVQ
                     VEEGGLLSALLPECSNFWVNSLHGQGAKVVSPRLRVEARSPDGLVEAVSVINHPFALG
                     VQWHPEWNSSEYALSRILFEGFITACQHHIAEKQRL"
     gene            51883..53301
                     /gene="puuA"
                     /locus_tag="RN951_000727"
     CDS             51883..53301
                     /gene="puuA"
                     /locus_tag="RN951_000727"
                     /EC_number="6.3.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415813.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-putrescine ligase"
                     /protein_id="HDX2525776.1"
                     /translation="METNIVEVENFVQQSEERRGSAFTQEVKRYLERYPNTQYVDVLL
                     TDLNGCFRGKRIPVSSLKKLEKGCYFPASVFAMDILGNVVEEAGLGQEMGEPDRTCVP
                     VLGSLTPSAADPEFIGQMLLTMVDEDGAPFDVEPRNVLNRLWQQLRQRGLFPVVAVEL
                     EFYLLDRQRDAEGYLQPPCAPGTDDRNTQSQVYSVDNLNHFADVLNDIDELAQLQLIP
                     ADGAVAEASPGQFEINLYHTDNVLEACDDALALKRLVRLMAEKHKMHATFMAKPYEEH
                     AGSGMHIHISMQNNRGENVLSDAEGEDSPLLKKMLAGMIDLMPSSMALLAPNVNSYRR
                     FQPGMYVPTQASWGHNNRTVALRIPCGDRHNHRVEYRVAGADANPYLVMAAIFAGILH
                     GLDNELPLQEEVEGNGLEQEGLPFPIRQSDALGEFIENDHLRRYLGERFCHVYHACKN
                     DELLQFERLITETEIEWMLKNA"
     gene            53450..53614
                     /locus_tag="RN951_000728"
     CDS             53450..53614
                     /locus_tag="RN951_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2525777.1"
                     /translation="MPMIKSPHGEGGCVCAPPATDWTPPPLLPLLNRFDFRSTRPQTL
                     LRRGGSNYGY"
     gene            53604..54989
                     /gene="puuP"
                     /locus_tag="RN951_000729"
     CDS             53604..54989
                     /gene="puuP"
                     /locus_tag="RN951_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415812.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine/proton symporter PuuP"
                     /protein_id="HDX2525778.1"
                     /translation="MAINSPLNIAAQPGKTRLRKSLKLWQVVMMGLAYLTPMTVFDTF
                     GIVSGISDGHVPASYLLALAGVLFTAISYGKLVRQFPEAGSAYTYAQKSINPHVGFMV
                     GWSSLLDYLFLPMINVLLAKIYLSALFPEVPPWVWVVTFVAILTAANLKSVNLVANFN
                     TLFVLVQISIMVVFIFLVVQGLHKGEGVGTVWSLQPFISENAHLIPIITGATIVCFSF
                     LGFDAVTTLSEETPDAARVIPKAIFLTAVYGGVIFIAASFFMQLFFPDISRFKDPDAA
                     LPEIALYVGGKLFQSIFLCTTFVNTLASGLASHASVSRLLYVMGRDNVFPERVFGYVH
                     PKWRTPALNVIMVGIVALSALFFDLVTATALINFGALVAFTFVNLSVFNHFWRRKGMN
                     KSWKDHFHYLLMPLVGALTVGVLWVNLESTSLTLGLVWASLGGAYLWYLIRRYRKVPL
                     YDGDRTPVSET"
     gene            55123..55368
                     /locus_tag="RN951_000730"
     CDS             55123..55368
                     /locus_tag="RN951_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmjA family protein"
                     /protein_id="HDX2525779.1"
                     /translation="MNHDIPLKYFDIADEYATECAEPVAEAERTPLAHYFQLLLTRLM
                     NNEEISEEAQHEMAAEAGINPVRIDEIAEFLNQWGNE"
     gene            55681..57324
                     /gene="sapA"
                     /locus_tag="RN951_000731"
     CDS             55681..57324
                     /gene="sapA"
                     /locus_tag="RN951_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein SapA"
                     /protein_id="HDX2525780.1"
                     /translation="MRQVLSSLLVIAGLVSGQAIAAPESPPHADIRDSGFVYCVSGQV
                     NTFNPSKASSGLIVDTLAAQFYDRLLDVDPYTYRLMPELAESWEVLDNGATYRFHLRR
                     DVPFQKTDWFTPTRKMNADDVVFTFQRIFDRNNPWHNVNGSNFPYFDSLQFADNVKSV
                     RKLDNHTVEFRLAQPDASFLWHLATHYASVMSAEYARKLEKEDRQEQLDRQPVGTGPY
                     QLSEYRAGQFIRLQRHDDFWRGKPLMPQVVVDLGSGGTGRLSKLLTGECDVLAWPAAS
                     QLSILRDDPRLRLTLRPGMNVAYLAFNTAKPPLNNPAVRHALALAINNQRLMQSIYYG
                     TAETAASILPRASWAYDNEAKITEYNPAKSREQLKSLGLENLTLKLWVPTRSQAWNPS
                     PLKTAELIQADMAQVGVKVVIVPVEGRFQEARLMDMSHDLTLSGWATDSNDPDSFFRP
                     LLSCAAIHSQTNLAHWCDPKFDSVLRKALSSQQLAARIEAYDEAQSILAQELPILPLA
                     SSLRLQAYRYDIKGLVLSPFGNASFAGVYREKQDEVKKP"
     gene            57321..58286
                     /gene="sapB"
                     /locus_tag="RN951_000732"
     CDS             57321..58286
                     /gene="sapB"
                     /locus_tag="RN951_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease SapB"
                     /protein_id="HDX2525781.1"
                     /translation="MIIFTLRRILLLIVTLFLLTFVGFSLSYFTPHAPLQGASLWNAW
                     VFWFNGLIHWDFGVSSINGQPIAEQLKEVFPATMELCILAFGFALIVGIPVGMIAGIT
                     RHKWQDNLINAIALLGFSIPVFWLALLLTLFCSLTLGWLPVSGRFDLLYEVKPITGFA
                     LIDAWLSDSPWRDEMIMSAIRHMILPVITLSVAPTTEVIRLMRISTIEVYDQNYVKAA
                     ATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAI
                     RQQDYAAISAGVMVCGSLVIIVNVISDILGAMANPLKHKEWYALR"
     gene            58273..59163
                     /gene="sapC"
                     /locus_tag="RN951_000733"
     CDS             58273..59163
                     /gene="sapC"
                     /locus_tag="RN951_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease SapC"
                     /protein_id="HDX2525782.1"
                     /translation="MPYDSVYSEKRPPGTLRTAWRKFYSDASAMVGLYGCAGLAVLCI
                     FGGWFAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGA
                     FVVTLAATICGLVLGTFAGATHGLRSAVLNHILDTLLAIPSLLLAIIVVAFAGPSLSH
                     AMFAVWLALLPRMVRSIYSMVHDELEKEYVIAARLDGASTLNILWFAVMPNITAGLVT
                     EITRALSMAILDIAALGFLDLGAQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMIS
                     VLLVNLLGDGVRRAIIAGVE"
     gene            59163..60155
                     /gene="sapD"
                     /locus_tag="RN951_000734"
     CDS             59163..60155
                     /gene="sapD"
                     /locus_tag="RN951_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapD"
                     /protein_id="HDX2525783.1"
                     /translation="MPLLDIRNLTIEFKTGDEWVKAVDRVSMTLTEGEIRGLVGESGS
                     GKSLIAKAICGVNKDNWRVTADRMRFDDIDLLRLSARERRKLVGHNVSMIFQEPQSCL
                     DPSERVGRQLMQNIPAWTYKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELT
                     EGECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHD
                     LQMLSQWADKINVLYCGQTVETAPSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLN
                     TLPGAIPLLEQLPIGCRLGPRCPYAQRECIVTPRLTGAKNHLYACHFPLNMEKE"
     gene            60157..60963
                     /gene="sapF"
                     /locus_tag="RN951_000735"
     CDS             60157..60963
                     /gene="sapF"
                     /locus_tag="RN951_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapF"
                     /protein_id="HDX2525784.1"
                     /translation="MIETLLEVRNLSKTFRYRTGWFRRQTVEAVKPLSFTLREGQTLA
                     IIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSFRSQRIRMIFQDPSTSLN
                     PRQRISQILDFPLRLNTDLEPEQRRKQIIETMRMVGLLPDHVSYYPHMLAPGQKQRLG
                     LARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHIGMMKHIS
                     DQVLVMHQGEVVERGSTADVLASPLHELTKRLIAGHFGEALTADAWRKDR"
     gene            61031..61384
                     /locus_tag="RN951_000736"
     CDS             61031..61384
                     /locus_tag="RN951_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF559 domain-containing protein"
                     /protein_id="HDX2525785.1"
                     /translation="MIDKIKSNARDLRRNLTLQERKLWRYLRSRRFSDFKFRRQHPVG
                     SYILDFACCSARVVVELDGGQHDLAVAYDSRRTSWLESQGWTVLRFWNNEIDCNEETV
                     LENILQELNRRSPSP"
     gene            61752..62540
                     /gene="fabI"
                     /locus_tag="RN951_000737"
     CDS             61752..62540
                     /gene="fabI"
                     /locus_tag="RN951_000737"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HDX2525786.1"
                     /translation="MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKL
                     KGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDG
                     DYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMG
                     LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRR
                     TVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELELK"
     gene            62684..63811
                     /locus_tag="RN951_000738"
     CDS             62684..63811
                     /locus_tag="RN951_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415803.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CMD domain-containing protein"
                     /protein_id="HDX2525787.1"
                     /translation="MEQRHITGKSHWYHETQSSTTEYDVLPLVPEAAKVSDPFLLDVI
                     LEKETLAPFLSWLDPARVLAVDLFPDQLTVTRSQTFTAYERLSTALTVAQVCGVQRLC
                     NYYSARLTPLPGPDSTRESNHRLAQITQYARQLASSPSIIDNRSRQHLNDVGLTAWDC
                     VIISQIIGFIGFQARTIATFQAYLGHPVRWLPGLEIQNYADASLFADESLRWRSSYEV
                     EKLPEEHTKSSTAELCQLAEILSLHPISLSLLEKLLNSTRGNTQPDNQLAALLCARIN
                     GSPACFATCMDSSNEYKKISTLMRKGENEINQWADRHSVERATVQAIQWLTRAPDRFS
                     AAQFSPLLEHEKSSTQIINLLVWSGLCGWINRLKIALGETY"
     gene            63879..65813
                     /gene="rnb"
                     /locus_tag="RN951_000739"
     CDS             63879..65813
                     /gene="rnb"
                     /locus_tag="RN951_000739"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exoribonuclease II"
                     /protein_id="HDX2525788.1"
                     /translation="MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSY
                     FIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPD
                     HPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVP
                     WWVTLARHNLEKEAPDGVATEMLDEGLVREDLTALDFVTIDSASTEDMDDALFAKALP
                     DDKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRAN
                     EVRPVLACRMTLSADGTIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWQPESEAIA
                     EQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEA
                     MIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFC
                     KLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINH
                     RLLKAVIKGETATRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKAGTDTRFAA
                     EIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVI
                     DVTIAEVRMETRSIIARPVA"
     gene            complement(65891..65995)
                     /locus_tag="RN951_000740"
     CDS             complement(65891..65995)
                     /locus_tag="RN951_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2525789.1"
                     /translation="MTYMKLTAAKRIVFFIYLFVIQFWKNASFQTKVS"
     gene            66049..68034
                     /gene="pdeR"
                     /locus_tag="RN951_000741"
     CDS             66049..68034
                     /gene="pdeR"
                     /locus_tag="RN951_000741"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HDX2525790.1"
                     /translation="MKTVRESTTLYNFLGSHNPYWRLTESSDVLRFSTTETTEPDRTL
                     QLSAEQAARIREMTVITSSLMMSLTVDESDLSVHLVGRKINKREWAGNASAWHDTPAV
                     ARDLSHGLSFAEQVVSEAHSAIVILDSRGNIQRFNRLCEDYTGLKEHDVIGQSVFKLF
                     MSRREAAASRRNNRVFFRSGNAYEVELWIPTCKGQRLFLFRNKFVHSGSGKNEIFLIC
                     SGTDITEERRAQERLRILANTDSITGLPNRNAMQDLIDHAINHADNNKVGVVYLDLDN
                     FKKVNDAYGHLFGDQLLRDVSLAILSCLEHDQVLARPGGDEFLVLASNTSQSALEAMA
                     SRILTRLRLPFRIGLIEVYTSCSVGIALSPEHGSDSTAIIRHADTAMYTAKEGGRGQF
                     CVFTPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITWRGEVRSLEALVRWQSPER
                     GLIPPLDFISYAEESGLIVPLGRWVILDVVRQVAKWRDKGINLRVAVNISARQLADQT
                     IFTALKQVLQELNFEYCPIDVELTESCLIENDELALSVIQQFSQLGAQVHLDDFGTGY
                     SSLSQLARFPIDAIKLDQVFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVESAKE
                     DAFLTKNGINERQGFLFAKPMPAVAFERWYKRYLKRA"
     gene            68182..68355
                     /locus_tag="RN951_000742"
     CDS             68182..68355
                     /locus_tag="RN951_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2525791.1"
                     /translation="MSEFDAQRVAERIDIVLDILVAGDYHSAIHNLEILKAELLRQVA
                     ESTPDIPKAPWEI"
     gene            68445..69194
                     /locus_tag="RN951_000743"
     CDS             68445..69194
                     /locus_tag="RN951_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDX2525792.1"
                     /translation="MNSRQQTILQMVIDQGQVSVTDLAKATGVSEVTIRQDLNTLEKL
                     SYLRRAHGFAVSLDSDDVETRMMSNYTLKRELAEFAASLVQPGETIFIENGSSNALLA
                     RTLGEQKKNVTIITVSSYIAHLLKDAPCEVILLGGVYQKKSESMVGPLTRQCIQQVHF
                     SKAFIGIDGWQPETGFTGRDMMRTDVVNAVLEKECEAIVLTDSSKFGAVHSYSIGPVE
                     RFNRVITDSKIRASDLMHLEHSKLTVHVVDI"
     gene            69463..69681
                     /gene="osmB"
                     /locus_tag="RN951_000744"
     CDS             69463..69681
                     /gene="osmB"
                     /locus_tag="RN951_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotically-inducible lipoprotein OsmB"
                     /protein_id="HDX2525793.1"
                     /translation="MFVTSKKMTAAVLAITLAMSLSACSNWSKRDRNTAIGAGAGALG
                     GAVLTDGSTLGTLGGAAVGGVIGHQVGK"
     gene            complement(69807..70133)
                     /gene="yciH"
                     /locus_tag="RN951_000745"
     CDS             complement(69807..70133)
                     /gene="yciH"
                     /locus_tag="RN951_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response translation initiation inhibitor
                     YciH"
                     /protein_id="HDX2525794.1"
                     /translation="MSDSNSRLVYSTETGRIDEPKAAPVRPKGDGVVRIQRQTSGRKG
                     KGVCLITGVDLDDAELTKLAAELKKKCGCGGAVKDGVIEIQGDKRDLLKSLLEAKGMK
                     VKLAGG"
     gene            complement(70133..70870)
                     /gene="pyrF"
                     /locus_tag="RN951_000746"
     CDS             complement(70133..70870)
                     /gene="pyrF"
                     /locus_tag="RN951_000746"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HDX2525795.1"
                     /translation="MTLTASSSSRAVTNSPVVVALDYHNRDDALAFVDKIDPRDCRLK
                     VGKEMFTLFGPQFVRELQQRGFDIFLDLKFHDIPNTAAHAVAAAADLGVWMVNVHASG
                     GARMMTAAREALVPFGKDAPLLIAVTVLTSMEASDLVDLGMTLSPADYAERLAALTQK
                     CGLDGVVCSAQEAVRFKQVFGQEFKLVTPGIRPQGSEAGDQRRIMTPEQALSAGVDYM
                     VIGRPVTQSVDPAQTLKAINASLQRSA"
     gene            complement(71064..72233)
                     /gene="lapB"
                     /locus_tag="RN951_000747"
     CDS             complement(71064..72233)
                     /gene="lapB"
                     /locus_tag="RN951_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapB"
                     /protein_id="HDX2525796.1"
                     /translation="MLELLFLLLPVAAAYGWYMGRRSAQQNKQDEANRLSRDYVAGVN
                     FLLSNQQDKAVDLFLDMLKEDTGTVEAHLTLGNLFRSRGEVDRAIRIHQTLMESASLT
                     YEQRLLAIQQLGRDYMAAGLYDRAEDMFNQLTDETDFRIGALQQLLQIYQATSEWQKA
                     IDVAERLVKLGKDKQRVEIAHFYCELALQHMASDDLDRAMTLLKKGAAADKNSARVSI
                     MMGRVFMAKGEYAKAVESLQRVISQDRELVSETLEMLQTCYQQLGKTAEWAEFLQRAV
                     EENTGADAELMLADIIEARDGSEAAQVYITRQLQRHPTMRVFHKLMDYHLNEAEEGRA
                     KESLMVLRDMVGEKVRSKPRYRCQKCGFTAYTLYWHCPSCRAWSTIKPIRGLDGL"
     gene            complement(72240..72548)
                     /gene="lapA"
                     /locus_tag="RN951_000748"
     CDS             complement(72240..72548)
                     /gene="lapA"
                     /locus_tag="RN951_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA"
                     /protein_id="HDX2525797.1"
                     /translation="MKYLLIFLLVLAIFVISVTLGAQNDQQVTFNYLLAQGEYRISTL
                     LAVLFAAGFAIGWLICGLFWLRVRVSLARAERKIKRLENQLSPATDVAVVPHSSAAKE
                     "
     gene            complement(72697..73461)
                     /gene="pgpB"
                     /locus_tag="RN951_000749"
     CDS             complement(72697..73461)
                     /gene="pgpB"
                     /locus_tag="RN951_000749"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase B"
                     /protein_id="HDX2525798.1"
                     /translation="MRSIARRTAVGAALLLVMPVAVWISGWRWQPGEQSWLLKAAFWV
                     TETVTQPWGVITHLILFGWFLWCLRFRIKAAFVLFAILAAAILVGQGVKSWIKDKVQE
                     PRPFVIWLEKTHHIPVDEFYTLKRAERGNLVKEQLAEEKNIPQYLRSHWQKETGFAFP
                     SGHTMFAASWALLAVGLLWPRRRTLTIAILLVWATGVMGSRLLLGMHWPRDLVVATLI
                     SWALVAVATWLAQRICGPLTPPAEENREIAQREQES"
     gene            73631..74221
                     /gene="ribA"
                     /locus_tag="RN951_000750"
     CDS             73631..74221
                     /gene="ribA"
                     /locus_tag="RN951_000750"
                     /EC_number="3.5.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase II"
                     /protein_id="HDX2525799.1"
                     /translation="MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHT
                     PVLARVHSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLNKI
                     RAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVNEVRLLTNNPKKVEILTE
                     AGINIVERVPLIVGRNPNNEHYLDTKAEKMGHLLNK"
     gene            complement(74285..76960)
                     /gene="acnA"
                     /locus_tag="RN951_000751"
     CDS             complement(74285..76960)
                     /gene="acnA"
                     /locus_tag="RN951_000751"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase AcnA"
                     /protein_id="HDX2525800.1"
                     /translation="MSSTLREASKDTLQAKDKTYHYYSLPLAAKSLGDITRLPKSLKV
                     LLENLLRWQDGNSVTEEDIHALAGWLKNAHADREIAYRPARVLMQDFTGVPAVVDLAA
                     MREAVKRLGGDTAKVNPLSPVDLVIDHSVTVDRFGDDEAFEENVRLEMERNHERYVFL
                     KWGKQAFSRFSVVPPGTGICHQVNLEYLGKAVWSELQDGEWIAYPDTLVGTDSHTTMI
                     NGLGVLGWGVGGIEAEAAMLGQLVSMLIPDVVGFKLTGKLREGITATDLVLTVTQMLR
                     KHGVVGKFVEFYGDGLDSLPLADRATIANMSPEYGATCGFFPIDAVTLDYMRLSGRSE
                     DQVELVEKYAKAQGMWRNPGDEPIFTSTLELDMNDVEASLAGPKRPQDRVALPDVPKA
                     FAASNELEVNATHKDRQPVDYVMNGHQYQLPDGAVVIAAITSCTNTSNPSVLMAAGLL
                     AKKAVTLGLKRQPWVKASLAPGSKVVSDYLAKAKLTPYLDELGFNLVGYGCTTCIGNS
                     GPLPDPIETAIKKGDLTVGAVLSGNRNFEGRIHPLVKTNWLASPPLVVAYALAGNMNI
                     NLASEPIGHDRKGDPVYLKDIWPSAQEIARAVEQVSTEMFRKEYAEVFEGTAEWKGIN
                     VTRSDTYGWQEDSTYIRLSPFFDEMQATPAPVEDIHGARILAMLGDSVTTDHISPAGS
                     IKPDSPAGRYLQGRGVERKDFNSYGSRRGNHEVMMRGTFANIRIRNEMVPGVEGGMTR
                     HLPDSDVVSIYDAAMRYKQEQTPLAVIAGKEYGSGSSRDWAAKGPRLLGIRVVIAESF
                     ERIHRSNLIGMGILPLEFPQGVTRKTLGLTGEEKIDIGDLQNLQPGATVPVTLTRADG
                     SQEVVPCRCRIDTATELTYYQNDGILHYVIRNMLK"
     gene            complement(77124..77219)
                     /locus_tag="RN951_000752"
     CDS             complement(77124..77219)
                     /locus_tag="RN951_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2525801.1"
                     /translation="MINTNMKYWSWMGAFSLSMLFWAELLWIITH"
     gene            complement(77333..77500)
                     /locus_tag="RN951_000753"
     CDS             complement(77333..77500)
                     /locus_tag="RN951_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588450.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2525802.1"
                     /translation="MVGQEQLESSPLCQHSDNETETKRECSVVIPDDWQLTSQQQAFI
                     ELFAEDDQPKQ"
     gene            complement(77503..77667)
                     /locus_tag="RN951_000754"
     CDS             complement(77503..77667)
                     /locus_tag="RN951_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmiA family putative membrane protein"
                     /protein_id="HDX2525803.1"
                     /translation="MLISDGDYMRLAMPSGNQEPRRDPELKRKAWLAVFLGSALFWVV
                     VALLIWKVWG"
BASE COUNT        18941 a        20265 c        19116 g        19410 t
ORIGIN      
        1 cagacttatt atcatttcag aggaattatt tgattaaggt tttacttaag gcgtaacaaa
       61 tgatatttat cggctaactg aacttctcct ttaggatgtt ttcactcccc gaaatgggga
      121 taaaaggcaa ataaaataac taaaggattt attcaatgaa aagcaaagta ctggcacttt
      181 taattcctgc cctgctcgcc gcaggtgctg cacatgcagc cgaagtttat aataaagacg
      241 gcaacaaatt agatctgtat ggcaaagttg atggcctgca ttatttttct gataattcag
      301 cgaaagatgg cgaccagagc tatgcgcgtc tgggttttaa aggcgaaacc caaattaacg
      361 atcaactcac tggctacggt caatgggaat acaatattca ggcaaacaac actgaatctt
      421 caaaaaacca gtcatggacc cgtctggcat ttgccgggct gaaatttgca gattacggtt
      481 ctttcgatta cggacgtaat tatggcgtaa tgtacgacat cgaaggctgg accgatatgc
      541 tgcctgaatt tggcggtgac tcttatacca atgcagacaa ctttatgact ggtcgagcca
      601 atggcgtcgc gacttatcgt aatactgatt tcttcggtct ggtaaatggt ctgaacttcg
      661 cggtgcagta tcaaggtaac aacgaaggag ccagtaatgg tcaggaaggc accaacaacg
      721 gacgtgatgt tcgccatgaa aacggtgacg gctggggtct ttccacaaca tatgatttag
      781 gcatgggctt tagcgctggt gcggcataca cctcttctga ccgcaccaat gaccaggtta
      841 accatactgc ggcgggtggt gataaagcag acgcgtggac tgctgggcta aaatacgatg
      901 ctaacaatat ttacctggca accatgtatt cagaaacgcg taatatgacc ccgtttggcg
      961 acagcgatta tgctgtggca aacaaaaccc agaattttga agtcactgca cagtaccagt
     1021 ttgattttgg tctgcgtccg gcagtctctt tcctgatgtc taaaggccgt gacctgcacg
     1081 ctgcgggtgg tgcagacaac ccggcaggtg ttgatgataa agatctggtt aaatacgccg
     1141 atattggcgc gacttactat ttcaataaaa acatgtccac ctacgttgac tataaaatca
     1201 acctgttgga tgaagatgac agcttctacg ctgccaatgg catctctacc gatgatattg
     1261 tcgctttagg tctggtttat cagttctaaa tcctcctgcc cgctgttatg gcgggctttt
     1321 tctgcttatt cttcctcctt tgatctaaat taaaaatgtg aactccgtca ttacacaaaa
     1381 agtgtcatct ggcgttacac tttatgcgga tactaaaaca ggaggtttta tgaacagaac
     1441 gattcttgtc cctatcgata tttccgattc agaattaact caacgcgtga ttagccacgt
     1501 tgaggaagag gcaaagattg atgatgcaga ggttcatttc ctgacggtaa taccttcact
     1561 gccctactat gcctctctgg gtttagcgta ttccgcagaa ttaccggcaa tggatgacct
     1621 gaaagcggaa gccaaatcgc aactggaaga gatcattaaa aaatttaaac tgccaaccga
     1681 cagagtgcat gtccatgttg aggaaggctc gcccaaagac cgcattctgg aattggcgaa
     1741 gaagatcccc gctcatatga tcatcattgc ttcccatcga ccggatatca ccacttatct
     1801 gctcggttcc aacgccgcag ctgtagtgcg tcacgcagag tgctccgtgc tggttgtgcg
     1861 ctgacactaa cgcccgcaca ttgctgcggg ctttttgatt catttcgcaa atgtgctgac
     1921 attttcccct ctaatccgta ccatacacgc cacagttttt tatatcagat ttcttatgct
     1981 gggcgttccg gcatgacgca tactcttctg atgccatata acgaattgag tcgcttttaa
     2041 atgtcgcaaa atcaagaaat tagtaagaaa gaacaataca acctgaacaa attacaaaaa
     2101 cgtctgcgtc gtaacgtggg cgaagccatt gctgacttca atatgattga agaaggcgat
     2161 cgcatcatgg tttgcctctc cgggggtaaa gacagctata ccatgctgga gattctgcgc
     2221 aatttgcagc aaagcgcgcc aatcaatttt tcgctggtgg ctgttaacct cgatcaaaag
     2281 caaccgggct tcccggaaca cgttctgccc gagtatcttg aaaagctggg cgttgagtac
     2341 aagattgttg aagagaatac ttacggtatc gtgaaagaga agattccaga gggcaaaacc
     2401 acttgctcac tgtgttctcg ccttcgtcgc ggtatccttt atcgtaccgc aacggaactg
     2461 ggggcgacga agatcgcgtt gggtcaccat cgtgacgata tcctgcaaac gttgttctta
     2521 aatatgttct acggcggtaa gatgaaaggt atgcctccga aactgatgag cgatgatggc
     2581 aaacatatcg ttattcgtcc gctggcctac tgccgcgaga aagatattca gcgatttgcc
     2641 gatgcaaaag cgttcccgat tattccgtgc aacctgtgcg gttcacagcc taacctgcaa
     2701 cgtcaggtga ttgctgacat gttgcgtgac tgggataaac gttatccagg gcgtatcgag
     2761 acgatgttca gcgcgatgca gaatgtggtg ccgtcgcatc tgtgcgatac caacctgttc
     2821 gatttcaaag gcatcaccca cggttctgaa gtggttaacg ggggtgatct ggcgtttgat
     2881 cgcgaagaga tcccactaca accggcgtgc tggcagccag aagaagatga aaatcagttg
     2941 gatgagttac ggctgaatgt ggttgaagtg aaataaccag gatagcgccc gatgcgcaag
     3001 cgtatcgggc tactcttatg gaggccggat aagacgcggc cagcgtcgca tccggcaatc
     3061 ccgaataaga tgtttactct tgcacccggc aattcaacat ttcattattt taataaccgc
     3121 acccggcacg tttttccttt aatcttcccg ccctgtaact gtttccatgc tttatgagca
     3181 acagcctgac ggaccgcgac atagacatgc gccggatgca cggcgatttt gccaatatct
     3241 gcgccatcaa gcccgatatc tcctgtcagt gcacctaata catcacccgg gcgcattttg
     3301 gcttttttcc cgccatcgat acacaacgtt gccatttctg cttccagcgt cgcaatggaa
     3361 ctattagctg gcggcgtttg ccagttaagt tttatctgca acatgtcaga aatgatattg
     3421 gcccgctgtg cttcttccgg agcacagaaa ctgatcgcca gaccgctatt tcctgcacga
     3481 gctgtacgac cgatgcgatg tacatgaact tcagggtccc acgccagctc aaagttcacc
     3541 accagctcaa gcgatttaat atccagacca cgcgcagcaa catcagtcgc gaccagtaca
     3601 cgggcgctac cgttagcaaa acgtaccagg gtctgatcgc gatcgcgttg ctccaaatcg
     3661 ccgtgtaatg acaatgcact ttgccctact tcattcagcg cgtcgcagac agcctggcaa
     3721 tcttttttgg tattgcaaaa caccacgcaa gaggatggct gatgcaagct taataaccgt
     3781 tgcaacagag gaattttgcc tttgctggat gtctcataaa attgttgttc aatgggtggc
     3841 aaagcatctg ttgagtcaat ttcaatcgcc aaaggatcgc gttgcactcg tccgctgatt
     3901 gcagcgatgg cttccggcca ggttgccgaa aacagaagcg tctgtcgaga tgcaggcgca
     3961 aaacggatga catcatcaat ggcatcgcta aatcccatat ccagcatgcg gtcggcctca
     4021 tccatcacca gcgtattcaa cgcatccagt gataccgtgc ctttttgcag gtgatccagc
     4081 aaacgccccg gcgttgccac gataatatgc ggcgcatgtt gcaacgaatc acgctgcata
     4141 ccgaacggtt gaccaccgca caacgtcaaa attttggtat ttggcagaaa acgcgccagc
     4201 cgacgcaatt cacctgccac ctgatccgcc agttcacgcg taggacacag cactaaagcc
     4261 tgggtttgaa atagcgacgc atcaatttgc tgtaacaagc cgaggccaaa agccgccgtt
     4321 ttgccgctgc cggttttcgc ctgcacgcga acatcttttc cggcaagaat cgccggaagc
     4381 gcggcggcct gcaccggcgt catggttaaa taacccaact cattaaggtt cgtgagttgg
     4441 gcgggaggca aaacattcag ggtagaaaaa gcggtcacaa tctattctcg tggtcatcga
     4501 cgcaaagtta gcaggcgcgt atcctcgcag atctacgctc acgatgcgac aatttaatcg
     4561 gttcttcatc gggtggtggg tcaggcatgg gttgcgggcg agggatcgga tcgggcactg
     4621 gaacaggatc gccaggaatc ggttcaggga caggaatttg caaataaata agtgtcgtca
     4681 tatttccctc tggtcattgg gtggactctt aaagggtaga cgctgataaa taacaggcaa
     4741 aaaaaagccg actcatcaaa gtcggcgtcg tacgaatcaa ttgtgctatg cagtaattca
     4801 aaaaaggaag taagacaata tggagcgcaa cgcccatcgc ttgacgttgc attcacctgc
     4861 aagagagata ttgccctgaa tgggtagaga gtttattgac ttcgctcaaa ctttgcggcg
     4921 tttttgtata cagacagccg gaaaaattgc ttttgttaca accatttact acgatgcaac
     4981 cataaagcaa caccaccaat aagaacaact aacagaatac aaaaaattga aaatccgaat
     5041 tgccacccgc cgccagggat cccaccaagg ttgacgccaa ataacccggt cagaaaggta
     5101 ctgggtaaaa agaccattgc catcaacgac attgtatagg tacgacgagc taaattttcc
     5161 tgcatcacct gagcgatttc atccgccatc acgccagtcc gtgctataca ggcgtcgatt
     5221 tcgtcaaggc cgcgcccaag gcgatcggca atatcctgca tccgacggcg ttggtcatcg
     5281 ctcatccacg gcaaacgttc actggcaaga cgagcataaa catcacgttg cggtgccata
     5341 tagcgacgca tcacaattaa ttgtttgcgc agcagagcca ggaatccacg cggtggaatt
     5401 tgctgatcaa ggagattatc ttcaaggtcg ataattttat cgtgcagctg ctcgataaat
     5461 tcactggaat gatcggtcaa cgcatcgcac acatccacca gccatccccc gcaatcggtc
     5521 ggacccgtgc cctcttccag atcgctcacc acatcgtcca gcgccagcac tttgcgttgt
     5581 cgggtcgaaa caattaaccg cccgtccata tatacacgca tggcgaccag ttgatcgggg
     5641 cgttcatcgg tgctgccgtt tatacagcgc aatgtaatca gcgtgccttc accgagacgg
     5701 ctgactcggg gacgcgtgct ctcgcccgcc agcgcatcac gtacgttatt gggaagcagc
     5761 ggtgttgtcg ccagccattg ggcgctatca tggtgtacat aattaaggtg gagccaacag
     5821 ggatgcgctt catcaatcac atctgtattt tccagcggtt taacgccgcc tctaccatcc
     5881 agcatccagg caaatactgc atccgggaca ttaacgtccg atcccttaat cgcttccaca
     5941 gtgcctccat catcaacgca ttattttgta gtctagcctt ctggccctgt tacgcaacat
     6001 ctcatcaccc cattaccctg aaatgattaa taaaattctg tctaaattga atacaaaaag
     6061 caaaatgctt ttccgtatac aaaccgtgtg aagtgttaaa tagcgtctat cattatcaga
     6121 attatctgat catatgacgt ggcttttttg cgatcggata gcaacaaaaa ttgataaaaa
     6181 taacgggatc tcaatgatta cgcacaactt caataccctg gacttactca ccagtcctgt
     6241 ctggatcgtt tcgccctttg aggaacagtt aatttatgcc aatagcgcgg cgaaactgtt
     6301 gatgcaagac ctcacgttta gtcagctacg aaccggaccc tattccgtct cctcacaaaa
     6361 agaactgccg aaatacctct ccgatctgca aaaccaacac gatattatcg aaatcctcac
     6421 tgttcagcgt aaagaagagg aaacagcatt gagctgtcgg cttgttttgc gaaagctgac
     6481 agaaacagaa ccggtgatta ttttcgaagg tatcgaagcg ccggcaacgc tgggtttaaa
     6541 agccagtcgc tcggcaaatt atcagcgcaa aaaacaaggt ttttatgcgc gcttttttct
     6601 gactaactct gcaccaatgt tgttgattga cccgtcacga gatggacaaa tcgtcgatgc
     6661 taacctcgcc gcgctcaatt tctatggtta taaccatgaa acgatgtgcc agaaacatac
     6721 ctgggaaata aatatgctcg ggcgtcgcgt catgcctatc atgcatgaaa tctcgcattt
     6781 acccggtggt cataaacctt tgaattttgt tcataaactg gcggatggtt cgactcgtca
     6841 tgtgcagacc tatgccggac cgattgaaat ttatggcgac aagctcatgt tatgtattgt
     6901 gcatgatatt actgagcaaa aacggctgga ggagcagctg gaacatgctg ctcaccatga
     6961 cgcgatgacc ggattactga atcggcgaca gttttatcac attacggaac caggccaaat
     7021 gcagcatctc gccatcgctc aggattacag cttgttgctc atcgacaccg atcgttttaa
     7081 acacattaac gatctctatg ggcattctaa aggtgatgag gtgttatgcg ccctcgcccg
     7141 caccctcgaa agttgcgctc gcaaaggcga tttggtgttt cgttggggag gcgaagagtt
     7201 tgtcttattg ctaccaagaa ccccactgga taccgcgctt tcgctggctg aaactatccg
     7261 cgtaagcgtg gcaaaagtga gtatttcggg cttaccacgc tttaccgtca gcattggtgt
     7321 ggcgcatcac gaaggaaatg aaagcatcga tgaactgttt aaacgcgttg atgatgcttt
     7381 gtatcgggcg aaaaatgatg gacgcaaccg cgtgctggcg gcataagccg cggatgcatc
     7441 tcgagatcaa cgactgcgct tagcgtggcg ctcccagttt tcttgcttcg cctgcgccgt
     7501 tttacgtagt gcgacgtaac acgccccgct gccgccatga tgcggtagcg cggtgcaata
     7561 tgcctgaaca tcatcaaatt cggtcagcca gcgcgccaca tagctgcgga caatattggc
     7621 atgcgattta tcatcccgcc ctttaccatg aataatcagc acgttacgca aaccatccgc
     7681 cagggcttgt tgaataaaac tgaacaccat tttgcggcac tcttccaccg gctggcgcaa
     7741 aagattcagg ctcgcctgtt gcggatattt accactgcgc agcttatcca gcaccccatg
     7801 ttgcaaccct tcccgccgaa actccagcgg ctgacttagt gggatgatgt cgagaaatcc
     7861 ggtggtgagg aaattatcaa gctgcagcgt gtcgatacgc tgcggcgcac gttggttacg
     7921 cgttggatgc cagtggacat cggtagcacg tttcagcggc tggacatctt ccatggcgtc
     7981 aagaaacagc gatttgtcgt caaggttcat gttacatcct cccgcaatta agagcgcgat
     8041 atgataacca gaccgggtcg gtccaacaac gtattaccca aatttccagt aataagttcc
     8101 aaatattgcc gatattttaa gcaaaatact tatgcatgat tattcattca cgatattaat
     8161 aatgtaactt atattttcgt gaaatctgtc actgaagaaa attggcaact aaaggttaaa
     8221 accgttataa cacagtcacc ggcgcagagg agacaatgcc ggatttaaga cgcggatgca
     8281 ctgctgtgtg tactgtagag tctggcggat gtcgacagac tctatttttt tatgcagttt
     8341 taactttgca gatagccgca ttctcgccgg aattgcgtga ttaatgacgc ggtcagtggt
     8401 gtctggcgac tatcacgccg ctgaatcaaa taataggccg ctttcggtaa aatttcgcta
     8461 accggcaaca tcaccagccc ctgtccgtgc aagggatcgc agcccatttc ttcaggcagt
     8521 atgctgagaa aatcgctttt tgccaccaga ctgatacagg ctgagaacgt ctcgcagact
     8581 acaccgacct gtggcgtttg cgcctgatcg tcaagcaatt cactcaactg tttgtagtag
     8641 ctgccgtgtg gcgtcggcat tgtccagctg taatccagta actgtttgat cgaacgggca
     8701 ccaatggcgg ggtgtcccgg gcggcaaaag atcgcgaatt gcttttccag taatttctca
     8761 aaagtaaatt cgtggtcgta cggtccctga taataggtat tgatggtgaa atccaattct
     8821 ccctgacgca attcattaat catcgacacc agttgccctt ccataatgcg tacttttacc
     8881 tgcggatgct gctgatgaaa acgagatatg acagctggca tcagactgcg ggaaatactg
     8941 gcccccatgc cgatattaat ctgccctgcc agttgccctt gtcgttggcg aatatcctct
     9001 tgggctgcac gcagctcttc aagaattaga ctggcgtgct gataaaaact ttcaccggca
     9061 tcagttaacg tcacgccttt actacggcga aaaaagagtt gcgccgctaa cccttcttct
     9121 agctcctgaa tagatttact cagtgccggt tgcgacatat tcaacattcg gctcgctccg
     9181 cgaatgctgc cctgacgagc cacttcaaca aaagcccgaa tttgatgaat ttttacctga
     9241 aaagccatga cgccaccgat aaccgttatt tatcagacca aagaaactgg catctacttt
     9301 aatgcagatg attgtgtcag ggtaatttat gaacggttaa aactgtgaaa aatcagttag
     9361 tgataagtaa aaactatcgc tacgtgaacc gggtcacact ttttactgat gacgggaaag
     9421 gttatggagt ctttgaatca atttgttaat tcgcttgccc caaaattatc gcactggcga
     9481 cgtgattttc atcactatgc agagtctggc tgggtggaat tccgcactgc cacccttgtt
     9541 gcggaagaat tgcaccagct cggctattca ctggcgctgg gtcgcgaagt agttaatgaa
     9601 agtagccgga tgggattacc tgatgaattc actctacaac gcgaattcga gcgcgctcgt
     9661 caacagggtg cgctagcaca atggattgcg gcttttgaag gtggtttcac tggtatcgtc
     9721 gccaccctgg ataccggtcg ccccggtccg gtgatggctt tccgtgtcga tatggacgcg
     9781 ctggatctca gtgaagagca ggatgtcagc catcgcccct accgcgacgg ttttgcgtca
     9841 tgtaacgccg gaatgatgca tgcctgtggt catgatggac ataccgccat tgggcttggg
     9901 ctggcgcata cccttaaaca gttcgagtcc ggactacatg gcgtcatcaa actgattttt
     9961 cagcctgcag aggaaggtac gcgtggcgcg cgggcgatgg tcgatgcagg tgtcgtagat
    10021 gatgttgatt attttactgc cgtgcacatt ggcactggcg tacctgcggg caccgtggtg
    10081 tgcggcagtg ataattttat ggcaaccacc aaatttgacg cgcacttcac cggtaccgcc
    10141 gctcacgcag gcgcaaaacc agaagacggt cacaatgcct tgttggcggc agcacaagcc
    10201 actcttgcac tgcatgcaat cgccccgcac agcgaaggag cttccagagt aaacgtgggc
    10261 gttatgcagg caggaagcgg tcgtaacgtt gttcctgcct cggcgttgct gaaagtggaa
    10321 acacgcgggg ccagcgacgt cattaatcaa tatgtttttg accgtgcaca acaagcgatt
    10381 cagggcgcag caaccatgta tggtgtcggc gttgaaactc gtctgatggg tgcagctacc
    10441 gccagttctc cttcgccgca atgggtcgca tggttgcaaa gtcaggcggc tcaggtcgcg
    10501 ggggtcaatc aggccattga acgtgttgaa gcgcctgcgg gttccgaaga tgccacatta
    10561 atgatggccc gcgtgcagca acatcaaggg caagcctcct acgtggtgtt tggcacacag
    10621 ctggcggcag gtcatcacaa cgaaaaattc gattttgacg agcaggttct cgctattgcc
    10681 gtcgaaacgc tggcgcgcac cgcgctcaat tttccctgga cgcgaggtat ctgatgcagg
    10741 aaatctatcg ttttatcgac gatgcgattg aagccgatcg ccaacgttat accgatattg
    10801 ccgatcaaat ctgggatcat ccagaaacac gttttgaaga gttctggtca gcggagcatc
    10861 tggcttcggc gctggaatct gcaggcttca ccgttacccg caacgtaggc aatatcccaa
    10921 atgcctttat tgcttcgttt ggtcaaggca aaccggttat cgccctgctg ggagaatatg
    10981 acgccctggc aggtttaagt cagcaagcag gttgcgcgca acctacatcc gtgacgcccg
    11041 gtgaaaatgg tcacggttgc ggacacaatt tgctgggaac cgccgccttt gccgctgcaa
    11101 tagccgtcaa gaaatggctg gaacaatatg ggcaaggcgg cacggtgcgc ttttatggtt
    11161 gtcctggcga agaaggcggc tcgggtaaaa cgttcatggt tcgcgagggg gtatttgatg
    11221 atgtggatgc ggcactcacc tggcacccgg aagcctttgc cggtatgttc aatacccgca
    11281 cgctggcaaa cattcaggca tcatggcgct ttaaagggat cgcagcacat gccgcgaatt
    11341 cccctcattt gggacgcagc gcccttgatg ccgtaacgtt gatgaccact ggcaccaact
    11401 tcctcaacga acatattatt gaaaaagcgc gcgtacacta tgccatcaca aatagcggcg
    11461 ggatctcgcc caacgtggtc caggcgcagg cagaagtgct ttatcttatc cgcgcccccg
    11521 aaatgaccga cgtgcagcat atttatgatc gggtcgccaa aatcgccgaa ggtgcggcat
    11581 tgatgaccga aaccacggtt gaatgccgct tcgacaaagc ctgttccagt tatctcccga
    11641 atcgcacctt agaaaatgcc atgtaccagg ccctatccca ttttggtacc ccggaatgga
    11701 actccgaaga actggctttt gcgaaacaaa ttcaggctac gctcacctcc aacgatcggc
    11761 aaaacagtct gaataatatc gccgcaaccg gtggcgaaaa cggcaaggtt tttgcactac
    11821 gtcatcgtga aacggtactg gcgaatgaag tcgctccata tgccgccacc gataacgtgc
    11881 ttgcggcatc gactgatgtc ggcgacgtca gttggaaact gcctgttgcc cagtgtttca
    11941 gcccctgttt tgccgtcggt acaccgctac atacgtggca actggttagc caggggcgaa
    12001 catctattgc tcataaagga atgctgctgg cggcgaaaac tatggcagca accacagtca
    12061 atctcttcct tgattcaggg ctattgcaag aatgccaaca agagcatcag caagtaacgg
    12121 acacgcaacc gtatcactgc cctatcccga aaaacgtgac accgtcacct ttaaaataac
    12181 aacaacaacg caaacacaac aaccgaggaa tgcccatgag tatgtcatcc ataccgtcgt
    12241 cctcccaatc cgggaagctc tatggctggg tcgaaagaat tggtaacaag gttccccatc
    12301 cttttctgct ctttatctat ttgattatcg tactcatggt gacgacggca attttgtcgg
    12361 cctttggcgt cagtgcgaaa aacccgaccg atggtacgcc ggtcgtggtg aaaaacctgc
    12421 tcagtgtgga aggattacac tggtttttac ccaatgttat taaaaacttt agcggttttg
    12481 ctccacttgg tgcgatcctg gcgctggttt taggtgccgg tctggcggag cgcgtcggct
    12541 tactgccagc actaatggtt aaaatggcat cgcatgttaa tgcccgctac gccagttata
    12601 tggtgctgtt tattgctttt ttcagccaca tttcttccga tgcggcgtta gtgatcatgc
    12661 caccgatggg tgcgctgatt tttctggcgg tgggcaggca tccagttgca ggtttactgg
    12721 ctgccattgc aggcgtaggt tgcggcttta cggctaattt actgattgtc acaaccgacg
    12781 tgttgctgtc ggggatcagc acggaagcgg cagctgcgtt caatccgcaa atgcacgtca
    12841 gtgtaattga taactggtat tttatggcca gctccgtagt cgtactgacg attgttggcg
    12901 gcctgataac cgacaaaatc atcgagccac ggttaggtca atggcaggga aacagcgatg
    12961 agaaactgca gacattgacc gaaagtcagc gttttggttt acgcatagca ggtgtcgtat
    13021 cgctactttt tattgctgcg attgcgctga tggtgatccc gcaaaacggg atattgcgcg
    13081 atccgattaa tcacaccgtg atgccatcac cctttattaa aggtatcgtg ccactgatca
    13141 ttcttttttt ctttgttgtc tcgctggctt atggcatcgc tacccgcaca attcgacgtc
    13201 aggcggattt accgcattta atgattgaac cgatgaaaga gatggcggga tttatcgtga
    13261 tggtttttcc cctcgcccaa tttgtcgcca tgtttaactg gagcaacatg gggaaattca
    13321 tcgccgtggg gctgaccgat atactggaaa gttcagggct tagcggcatc ccggcgtttg
    13381 tcggtctggc gttgctttcc tctttcttat gcatgtttat tgccagcggt tccgcaatct
    13441 ggtcgattct tgcccccatt ttcgtaccaa tgtttatgct acttggcttt cacccggcat
    13501 ttgcgcaaat cctctttcgt attgccgact catccgtatt gcctttagcg ccggtatctc
    13561 cttttgttcc actgtttctt ggattcctgc aacgctacaa accagacgcg aaactgggta
    13621 cttactattc gttagtcttg ccctatccac ttatcttttt ggtggtatgg ctgctgatgt
    13681 tgctggcgtg gtatcttgtc ggtctgccga taggtccggg tatttaccca cgtttgtctt
    13741 aagagagaac ggatgctgag attacttgaa gaaaaaattg ccacgccact gggtccactg
    13801 tgggtgattt gcgatgagca atttcgcctg cgggcggttg aatgggaaga gtacagcgaa
    13861 cgcatggtgc agctgctgga catccattat cgcaaagaag gctatgagcg catttctgcc
    13921 accaatccag gcggtttaag cgacaagctt cgtgaatatt ttgccggtaa tcttagcatt
    13981 attgatacgc ttcccactgc tacggggggg acgccatttc agcgcgaagt ctggaaaaca
    14041 ctacgcacta tcccctgcgg gcaggtaatg cattacggcc aactggctga gcaattgggc
    14101 cgtcctggcg cggcgcgtgc cgttggtgcg gcaaacggat cgaatcccat cagcatcgtc
    14161 gtaccttgcc atcgggttat tggccgaaac ggcaccatga ccggatatgc aggcggagtt
    14221 cagcgaaaag agtggttatt gcgccatgaa ggttatcttt tgctgtaaac attaaacaat
    14281 ttgtgccagc ttgttcacac ttttatgtaa agttaccctt aacaacttaa gggttttcaa
    14341 atagatagac atatatttac atctaatatc ggaattctct gctgttaagg tttgcttaga
    14401 cttacttgct ccctaaaaag atgttaaaat tgacaaatat caattacggc ttgagcagac
    14461 ctatgatccc ggaaaagcga attatacggc gcattcagtc tggcggttgt gctatccatt
    14521 gccaggattg cagcatcagc cagctttgca tcccgttcac actcaacgaa catgagcttg
    14581 atcagcttga taatatcatt gagcggaaga agcctattca gaaaggccag acgctgttta
    14641 aggctggtga tgaacttaaa tcgctttatg ccatccgctc cggtacgatt aaaagttata
    14701 ccatcactga gcaaggcgac gagcaaatca ctggtttcca tttagcaggc gacctggtgg
    14761 gatttgacgc catcggcagc ggccatcacc cgagcttcgc gcaggcgctg gaaacctcga
    14821 tggtatgtga aatcccgttc gaaacgctgg acgatttgtc cggtaaaatg ccgaatctgc
    14881 gtcagcagat gatgcgtctg atgagcggtg aaatcaaagg cgatcaggac atgatcctgc
    14941 tgttgtcgaa gaaaaatgcc gaggaacgtc tggctgcatt catctacaac ctgtcccgtc
    15001 gttttgccca acgcggcttc tcccctcgtg aattccgcct gacgatgact cgtggcgata
    15061 tcggtaacta tctgggcctg acggtagaaa ccatcagccg tctgctgggt cgcttccaga
    15121 aaagcggcat gctggcagtc aaaggtaaat acatcaccat cgaaaataac gatgcgctgg
    15181 cccagcttgc tggtcatacg cgtaacgttg cctgattttt ccgcataact cactatcctt
    15241 ctgtcatatc attaaatttt tctgatttat tgatctggca gaaggttcat cactgtttca
    15301 ttcaccagat atgggttaat cttttaatta caaactgcgt tgacagttgt tgtaaggaga
    15361 ccctgtatgg ctatgtatca gaacatgctc gttgttatcg atcctaacca ggacgaccaa
    15421 ccagcattgc ggcgagctgt ttatttacat caacggattg gtggcaaaat taaagccttt
    15481 ttgccgatct atgacttctc atacgaaatg accaccctgc tctccccgga cgaacgtacc
    15541 gctatgcgtc agggcgtcat cagccagcgt acagcctgga tccacgagca ggcaaaatat
    15601 tatctcaatg ctggcgttcc cattgaaatt aaagtggtct ggcataaccg tcctttcgaa
    15661 gccatcattc aggaagtgat cagcggcgga cacgatttgg tgctaaaaat ggcgcaccaa
    15721 catgaccgtc tggaagcggt gatttttacg ccaacggact ggcatctgtt acgcaaatgc
    15781 ccaagcccgg tgtggatggt gaaagaccag ccgtggccgg aaggaggcaa ggcgctggtg
    15841 gcggtgaatc tcgccagtga agagccgtat cataatgcgc tcaatgaaaa actggtcaaa
    15901 gagacgatcg aactggcaga acaagtcaac cataccgaag ttcatctggt tggcgcttat
    15961 ccggtaacgc caattaatat cgcgattgaa ctgccggaat ttgacccgag cgtttataac
    16021 gatgccattc gtgggcaaca tttgctggca atgaaagccc tgcggcagaa attcggcatt
    16081 aatgaaaaca tgacgcacgt agaaaaaggt ctgccagaag aggtgattcc tgatttggcg
    16141 gagcacttac aggcggggat tgtggttctg ggcacggtag gacgcaccgg tatttcagca
    16201 gcattcctcg gcaacacggc ggaacaggtg attgatcatc ttcgctgcga cctgctggtc
    16261 attaaacctg accagtatca gacacccgtt gaactggatg acgaagaaga cgattaacga
    16321 ctcttcaata actgacaagg cccgagttat cgggcctatt ttttacttac tgctcttcgc
    16381 cgccaaggaa ataaattccc aacgggattg ccagcaacac agtaaagacc aggctataaa
    16441 caaaaatcat cgatgactga atcacataca ttgatgtcgt ccactcagac agcggaatat
    16501 tgtactgttc tataacgccg ccgatggtcg cgcgagtcac aaccgacgcc gcaataatga
    16561 aaaccgccaa caaaccaaag agaaatttct tccctttcgc tgacttcagt ttcgccataa
    16621 tcatgatgta atccttgtgc agacaaattt cttgttacct aaacgtaaca ataccatgac
    16681 atttcaccgt tgtctgctct gaaaacctca cctcttagct ggatttacaa tcaacgcatt
    16741 gattagttag ctaatgttgc tacttccttc cctgactatt gatgatctga atgaattgtc
    16801 gcggtaaaat agccccgcca ggggtttccg gcatgacgac aattatctgg aggagcctga
    16861 taaaacaatg atcgctgaac tgtttacaaa taatgcgctt aatctggtca ttattttcgg
    16921 tagctgcgca gcattgattc tgatgagctt ttggtttcgc cgtggaaatc gtaaaagaaa
    16981 aggattttta ttccatgcgg tgcaattttt aatctacacc ataattatca gtgctgttgg
    17041 tagcattatt aattatgtta tagaaaacta taaactcaaa tttatcaccc caggcgttat
    17101 cgattttatc tgtacgtccc tgattgcggt tattctgacg attaagctat ttctgctgat
    17161 taatcagttt gaaaaacagc agattaaaaa aggtcgcgat atcaccagtg cgcggattat
    17221 gtcgcgtatc atcaaaatca ccattattgt ggtgcttgtt ctgctttatg gcgaacattt
    17281 cggcatgagc ctttctggct tgctgacctt tggtggtatt ggtggtctgg ctgtcggtat
    17341 ggccggtaaa gatattctga gtaacttctt ttccgggatt atgctctatt tcgaccgtcc
    17401 tttcagtatt ggcgactgga tccgttcacc ggacagaaat atcgaaggta cagtagcgga
    17461 aattggctgg cgaattacca aaattacgac ctttgataat cgtccattgt acgtaccgaa
    17521 ctcgctgttt tcgtcgatca gcgtagaaaa cccaggacga atgaccaacc gccgcattac
    17581 cacgaccatt ggtttacgtt atgaggatgc ggcaaaagtg ggcgttattg tcgaagctgt
    17641 acgtgagatg ctgaaaaatc acccggccat cgaccagcga caaaccttac tggtttattt
    17701 caaccagttt gctgactctt cattgaatat tatggtttat tgctttacca aaaccacggt
    17761 atgggctgaa tggcttgctg cacagcaaga cgtttatttg aagattatcg atattgtaca
    17821 gtcacacggc gcggactttg ccttccccag ccagacgctg tatatggata acattacacc
    17881 gccggaacag ggtcgctaaa tcagacatca ctggcgttat gcacaagggt aacgccagtt
    17941 cccatcacat caatgcttca caatatacat agtccgactg tacgccacat cttcaggatt
    18001 attaatggga taacctttca gccacggctt gattaatcgt ccattggtat attgataaat
    18061 tggtgcaatc ggtgcttgct ccatgaggat tttttctgcc gcgttgtaat cggcattacg
    18121 cgctttaacg gtattttccg tcgatgcctg ggccagaact ttgtcatatg ccggattgtt
    18181 aaagcgtgaa atatttcctg aatgcgttga cgttaataat gtcaggaaag tggagggttc
    18241 attataatcc cccacccacg aggcgcggat aacatcaaaa ttgccggtgt tacggctatc
    18301 gatataggtt ttccattcct gattttgcaa tttaacatct acgccaaggt tctttttcca
    18361 catcgatgct acagcaatcg caattttttg atggttttct gaagtgttat acaaaagcgt
    18421 cagcttcagc ggtttttgcg gaccataacc agctgcgctc aacaaagttt ttgcctgcgc
    18481 attcagttct tcctgactca tttgttcaaa cggcgaaggt tccggcgtaa atcccgcggt
    18541 aacatctggt gtaaaatgcc acgctggctt ttcgcccgtc cctaatactt tttcggtcat
    18601 caggcggcga tctatcgtca tacttaatgc cagacgaacg cgctgatctg ccgtcggccc
    18661 tttttgcgtg ttaaacgcat aataataggt cccgagctgc ggcggcgtat aaacctgccc
    18721 cggaatatcc ttcaacagct tctgatacat atttttcggg aaggattcgg tgatatcaat
    18781 atcccccgcg aggtaacgct tagtggctgc ggattcctga ttaattggca ggaaggtcac
    18841 tttttgcagt accgttttgg cgttatccca ataatgggta ttcggtacca cgaccagttt
    18901 ttcattgact acgcgctctt taagaacata agcgccattg ccgatcagat ttccgggttt
    18961 cgtccactct ttaccgcttt ctacgttggc tttttgcacc gggaagaagg caaagttagc
    19021 ggttaaattc acaaaccacg gcaacggttt atcaagctga attttcaaag tatgggcatc
    19081 aactgcggtg acgccaagct ggtcaggcgt agctttacca tcaataatcg cctgtgcgtt
    19141 gttgattccc gccagcgcgg caaaccatgc aaatggcgac aatgtttttg ggtccaccag
    19201 acgttgccag ctgtagacaa aatcttgcgc cgttaccggt gtgccatccg cccattttgc
    19261 gttatcgcgc agggtaaaag tccagatacg gttgtcatta cttttccact gagtcgcaac
    19321 gccggggaca atctcccctt tttcgttctg attcaccaga ccttcaaaca gatcgcgaat
    19381 gacctgaatc tctggcaggc ccacggcttt agcgggatcc agcgacgcag gctcatcttt
    19441 aatgtggcgc accagctcct gcttctctgc cagtactgtg ccgctcggaa cttctgcagc
    19501 atacgaaaga gaaatgctgc tgaccaacag cgcacaacac gtgactgaaa cagagtgctt
    19561 cataagtttc cctctaaccg acattaaaat tgatgcgtaa ttatttgttt cgccttaaag
    19621 aaatgcaaac aacttccatc aaaaaagtga caaaggaagc atcaaatgtt ttaagtatca
    19681 atatatcaaa tcagatttag tgtaaataat agtctccaaa atgcggtaaa gcacatagaa
    19741 ctccgaacac tacgttcggg cttcgcacgt tcaaacccgt tttcggtatc ataatcagca
    19801 tctgtcgcca ttgtacgaag aataaaaaat gaccaaaacg ttgaaaggaa ctgagaatac
    19861 gttaagagaa gaattaaatt aatgtatcag caagtagtgc taaacagcac ctttatactt
    19921 cagcctatct ataaataatg agaatgccga gccagcatgt cgacggtgtg gatagtacag
    19981 gtgataaccg ggtaaatctg gtgtgaattt atccaaaaca cgtatcagtt ttttttcttt
    20041 aatagcccgc tcaacctgat cataaggtag atacgccaat ccatgcccat caattgcagc
    20101 atcaatgatc aggtctatcg tattcagtaa aagctgacct tccatgcgaa cacgaacttc
    20161 acgtccaccg cgtattaatc tccagcgatt tgctgtaccc gatgtgggaa gatacaaatt
    20221 aattgcctga tgatctatta attgtgacac tgacgttgga acacttcggc gagaaaaata
    20281 atccggtgag ccaacaatag ccattggtat atctggcccg attcgaatgg cgatcatatc
    20341 tttatccatc tccccaccca gacggacgcc tgcatcaaaa cgttcagaaa cgacatcggt
    20401 caaaccataa tcaatggtga gctgaatatc aatttcagga tgcgatttca ggaatgtgcg
    20461 cattgctggt aacaatatcg tttttgctgc atgttctaca gtagtaatac gtattgtccc
    20521 ggatgggcgg ttctgcagat cgctcaggga tgccatggct gaatctatgt catgcaacat
    20581 agggccaaga acagacaaaa gatgctcgcc cgcttcagtt ggaacaacgc tgcgcgtggt
    20641 tcgcgtcaga agccgcaatc ccaatcgttc ttctatacga cgcactatct ggcttaaagc
    20701 tgactgcgcc atgctcaggc gggctgctgc acgagtgaag ctacgctcct ctgcaacgac
    20761 gacaaacgcc atcagatcag cgatttcttc acgcttcatt cagtatctcc atgcaatcta
    20821 ttaatcattt aaatgatagg tctaatcatg attttgggtc taatcaactt aatgatcaat
    20881 atctaaagtg atatcaccaa ccgttaaaac gaaccgacaa ctccatgagg aacggaatga
    20941 taaataataa agtcagcttc actaacagca ataatccaac catctctttg tctgcagtga
    21001 tctatttccc tccaaaattt gatgaaaccc gtcagtatca ggcaattgtg ttatctcacc
    21061 caggtggggg cgttaaagaa caaacggccg gaacctatgc caaaaaactg gcggaaaagg
    21121 gatttgtcac tattgcttat gacgcatctt atcaaggtga aagtggcggc gagccgcgtc
    21181 agttagaaaa cccatacatt cgtactgaag acatcagtgc cgtgattgat tacctgacaa
    21241 cgctttctta tgtcgacaat acccgaattg gtgcgatggg aatttgtgcc ggtgcaggat
    21301 atacagccaa tgctgcaatt caggatcgcc gcatcaaggc catcggtacc gttagtgcgg
    21361 tcaatattgg ttcgatattc cgtaatggtt gggaaaacaa tgtgaaatct attgatgccc
    21421 tgccatacgt tgaagcgggt tcaaacgcca gaaccagcga tattagcagc ggagaatacg
    21481 ccattatgcc actggcacca atgaaggagt ccgatgcgcc gaacgaagaa ctgcgtcagg
    21541 cctgggagta ttaccacacc cctcgcgcgc agtatccaac agcaccgggt tacgctactt
    21601 tgcgcagcct taaccagatt attacctatg atgcttacca tatggcggaa gtgtacctga
    21661 ctcagccgac gcagattgtg gcgggcagcc aggcagggag caaatggatg agtgacgacc
    21721 tgtacgatcg agcatcaagc caggataaac gctatcacat tgttgaaggc gcaaaccata
    21781 tggatcttta tgacggcaaa gcctatgtgg ctgaagcaat ttcagtatta gctccgttct
    21841 ttgaggaaac tctgtaatga aacatattca aatccgcaat agtgatatgg actggcatat
    21901 tgctgccaat aatctgggat aattttcatg aaaaatgtac tgattcttgg tgctggcggt
    21961 cagatagccc gccatgtgat taatcaactg gcagataagc aaaccattaa acaaacttta
    22021 tttgcccgtc agccagcaaa aatccacaaa ccctatccaa ctaataaaat gcaaacaact
    22081 tccggcaaaa aagtgataca agatcgatga catagcgttg aagaaaagga tttgataatc
    22141 cgcaaaattt gcacaacact gcctgtaata cttcctgaac cagagacgat catgaccgta
    22201 acccgcccac gcgccgaacg cggcgcattt ccgcccggaa cagaacatta cggacgttca
    22261 ttattgggcg cgccgttaat ctggtttcct gcccctgcag ccagccgcga aagtggtttg
    22321 attctggctg gcactcacgg tgatgaaaac tcttcggtcg tcacgctctc ctgtgctctg
    22381 cggacgttga caccttcttt gcgccgtcat catgtggtgc tgtgtgtgaa tcctgacggc
    22441 tgccagttgg ggttacgggc caatgctaat ggtgtggatt taaacagaaa ctttccggcg
    22501 gcgaactgga aggaaggtga aaccgtttat cgctggaaca gcgccgctga agaacgcgat
    22561 gtcgtattac tgacaggtga caaacctggc tccgaacctg aaacccaggc gctgtgccag
    22621 cttatacacc gcattcaacc tgcctgggtg gtctcattcc acgatccact ggcctgtatt
    22681 gaagatccca gacacagcga attaggcgaa tggctggctc aggcgtttga attgcctctg
    22741 gtaaccagcg tcggttatga aacgcctggc tctttcggca gttggtgtga agatctgaac
    22801 ttgcattgca tcaccgcaga gtttccgccc atctcctccg acgaagccag cgaaaaatat
    22861 ctctttgcga tggcaaactt gctgcgctgg catcctaaag atgcaattcg cccgtcgtga
    22921 actgaagcgc cggttccaca tctaccgcca gccaggtcgg tccgtcaaga tcggcgaaac
    22981 tgacctgcgg caccagcggt aaagcggcgc taatggcacg agaggtacac aacatgcagc
    23041 ccagcatcag actgaaacct tgtgcacgcg cttcagtcgc cagcgccagc gcttccgtca
    23101 gacccccggt tttatcgagc ttaatattaa ccatctcata gcgccctttc agcgccttca
    23161 aattgctacg agtatgacaa ctttcatcag cacaaatcgg caacggatga ataaaattct
    23221 ccagcgccgc atcgtcctgc gcaggaagcg gttgttcaag catcgcaacg cctaaatccg
    23281 ccaatagctg gcaacgcgcc gccaaccctt ctgcacgcca ggattcattt gcatcaacga
    23341 tcagcgtcgc atcgggcaca gctgtgcgaa ttgccaccat ccgctcactg ataagatggt
    23401 tatccagctt cactttcagt aatttcgcgc ctgcctgcca gagtgttgat gcactattgg
    23461 ccatctgatc aggcgtaccg atgacaaccg tctgtgcagt gataactgtc tcgggaagcg
    23521 ttatgccgat caaatcagcc agcgattgct gctgtcttcg cgcggccaga tcccacaatg
    23581 cacaatccag cgcattacgt gctgcgccgg cagggagaat tttttgcaac tcctcccgtg
    23641 tcagcccttt ctctagttgc ggcacgacgc tcataatttg cgccattacc gaggcatcac
    23701 tttccccata acgcggatac ggcgtgcatt cgccggtgcc tttaataccc tcttcttcca
    23761 gttcaaccac caccacgcgc gcttcactgc gacttccccg ggcaatcaca aacggggtat
    23821 gtaagggcca ggcttcctcg aataccttaa cggttctcat ctttactcct tgttgtcgcg
    23881 gtggtctgcg gattaagcgc aaatagcgtt tgctgtgtta ttgacagtta gcataaacta
    23941 ggtgtgacgt taactatatg taaacaggaa agataatcat gtcacaaacc gttcatttcc
    24001 agggcaaccc ggttacagtc gccaattcca tcccgcaggc gggtagcaaa gcgcagactt
    24061 ttactctcgt ggcaaaagat ctgtctgacg tcaccctcgg tcagtttgcg ggtaaacgca
    24121 aagtgctgaa cattttcccg agtattgata ccggtgtttg cgccgcatca gtacgtaagt
    24181 ttaaccaact ggcaactgag atcgacaaca ccgttgtgct gtgtatctct gccgatctgc
    24241 cgttcgccca gtctcgtttc tgcggcgcag aaggtctgaa caacgttatc accctctcca
    24301 ctttccgtaa cgctgaattt ctgcaagctt acggtgtggc aattgctgat ggcccactga
    24361 aaggtctggc agcgcgtgcc gttgtggtta ttgacgaaaa tgacaatgtg attttcagcc
    24421 agctggtgga tgaaatcacc accgagccgg attacgaagc agctctggct gtactgaaag
    24481 cataatttaa tatgcctgat ggtgttgcac catcaggcat attcgcgctt actcttcgtt
    24541 cttcttctga ctcagaccat attcccgcaa cttattggca atcgcggtat gtgaaacgcc
    24601 gagacgtttt gccagtttgc gcgtgctggg ataattgcga taaagctggg ttaataccga
    24661 gcgttcaaaa cggctggtga tttcgtccag cgaaccttcc atcgcatctt cgcccacggc
    24721 taccgttgcg gcgtcataat ccggcaacaa aatatcctgt ggacgcagct cataaccgtc
    24781 cagttgtgtc agtgcgcgat agatagcgtt ctttaactgc cgcacatttc ccggccacgc
    24841 ataacgcgta agtacagtat tcaggtcagc ggccagtttc ggacgcggca cgccctgctc
    24901 gtcggcaaag cgggcgacga acagctcagt taacggcatg atgtcctgcg gacagtcacg
    24961 tagcggcggc agattgagcg tcaacacgtt cagacgataa tagagatctt cacggaacat
    25021 gcctttttgc accagttcga ccagattctt ctgcgtagcg caaatcaccc gcacatcgac
    25081 atgcacctca tggtcttcgc caacccgacg gaaagtgcca tcattaagga aacgcagtaa
    25141 tttcgcctgc atccgtggtg acatttcccc tatttcatcc aacagcaccg aaccaccgtt
    25201 cgcctgctca aagaatcctt tcttcccttc cggagcatga ccaaacagtt cactctcgac
    25261 cgcatcttcc ggtatagacg cacagttcag cgccaggtaa ggtttgcccg ctctggggct
    25321 tgcctgatgg caggcgtagg caaagagatc tttacctgta cctgtgtcac ccgtaatcag
    25381 cagcggcgcg cttagcatcg ccagtttctg cgcctgttcg acaacatgct tcattttcgg
    25441 gctgacggcg acaatttgac tgaaggcgct gacgtcctgg gcggcgacat tttgcaactg
    25501 gcggcccata cgaatcgttg atcgcaacat caccaccgca ccggtcagga cgtgttgatc
    25561 attttcatcc tgaagataaa caggcgtaat ctccatcagg aaattctgcc cattaataac
    25621 gacatgctcg ttatgcgaat cttgcggttc gctttccagc caacgtaaaa aattaaagcc
    25681 gttaatcaat tgtgcggcgg tatggttgcg caggcgatcc aatttttgcc caaaaagctg
    25741 acagctcgcc gggttcgcca tatccacttt gcttttcata tcgacagaga gcacaggttc
    25801 aggcaacgcc tccagtaacg cgctcaacgc cagatgctca cgttcggaag gcatccacgg
    25861 gacagtacgc acatcggtaa cacccgcaat acggcgtatt tcggccatca gactgctgaa
    25921 actctcaaac tccagttcag caaaattgag gtagattcgc ccaatgggat caatctcaat
    25981 accgcgtaaa tcaatgcctc ttagcacgag tagatcgagt aattcgcggg tcagaccgag
    26041 tcggtcttca caaaagactt ccagacgcat gggaaccttc acctgaaaaa agaacaatta
    26101 atatgatgat atgacactat ttggatagca ggaaggtttc tgtcaacaat cattgacaca
    26161 aagacggaaa aacgggcact tcggcgtaaa gatatccggt cagcacccga tattgcatta
    26221 tttttcgctg ggcgttttgc ctttttgcag cgtttctttc acctgaccga taagctgacg
    26281 acggaaatcc ccgaggcgag gtttgtcatc gtcaatccac ggcagcgggc ggcaaagctc
    26341 catagcttta atcccgagtc gtgccgtcag aagtcctgca ccaatcccct gagctgcgcg
    26401 ggtagacaaa cgagcagcga gatcttgcga catccagtcc atccccactt cgcgcaccag
    26461 ttcgctggct ccggcaaaag cgatattcag caataccagc ttaaacagac gcaaacggct
    26521 gtaatacccc agttcaatgc catacagcgt ggcgatgcga ttaattaaac gcagattgcg
    26581 ccaggcgata aacgccatat cgaccaacgc cagcgggctg accgcaatca tcaacgttga
    26641 ttccgccgcc gaacggctga tttcgcgccg cgcctgggca tctaaaactg gctggaccaa
    26701 atgcgcatac aggctgacca cttcacggtc gttttgcgtt tcatggattg aggcatacca
    26761 gcgttgcagc gccggatgcg actgatcaat acccgcctgc tgcgccagtt tttcgcaaaa
    26821 tgcgcggcct ttgcccgtgc cgtggctatg caataaatca cgcgcttcgt cgcgttcatg
    26881 ggcgcgctgt cgcaagcgcc ataagcgccg ccactctgtt accacagaac ctacgccagc
    26941 gccgataatc aatgccccag cggcacatcc acccagcgcc acccagtcct gggtttgcca
    27001 ggcattcatt gtccactgta caccctgccc gacaacgctt gcgccaaaca gagccagccc
    27061 tcccatcacc attttgcgcc acaggctgcg tttcggacgt aacgctgcgt ccattaccgc
    27121 ttcgacttgc ccctcttctt cctgcgcttc gtcgagcgtg gccggggcaa aattttgcgc
    27181 ctgattttcg tcaaaggtct gctgcgccct gaatttagga ttctgatcga cctccagagg
    27241 accgtcgaaa tcaatacgtg gttttaacgg ttcggtcatc gcaatttatc tcctattaaa
    27301 aattccagcg cagcatcaag acgaatatgc ggtagtggtt tgtcgacatc catcacctgc
    27361 ggacgaaatg cctcaaactg gaagccttgc ttatcccaga acgcctgacc aggcaaacgt
    27421 gcgggaactt cgccaggata aacagtgagc ggtgcgccat cgctaagtcg attaccacgc
    27481 agcgccggga ttttctcacc gttaacatca ataatgccgc tggtggtcgc ctgaactgac
    27541 gccagcccca ggcagtccat gctgatccct tcgaacgccg cattttgcca ggcatcctga
    27601 atcagttgtt gcagtaatga aaccatatta gcgtgctgat cgatggtcac atggtccgct
    27661 ttagtggcag caaacaatag cttatcgata accggcgaaa acaaacgccg gaacagggta
    27721 cgctgcccgt agtgaaaact ttgcatcagc tgcgtcagtg ccagacgcat atcattaaat
    27781 gcctgtggcc cactgttgag aggttgcagg caatccacca gcacaatctg gcggtcaaag
    27841 cgcagaaaat gattcttata gaaccccttc accaccttct cgcagtaata attaaagcgc
    27901 tcgcgcagca ttccggcatt ggtatgctta tcggcctgcg ccagtttgga ctcgccccag
    27961 gtatcgacat ccggccacgg gaagaattgc agcgcgggcg cacctgccat atctcccggc
    28021 aagacaaagc gcccaggctg aataaagtgc agcccctgct ctttacagtg gtggagataa
    28081 tcggtccacg cggcggcaat gtccgccagc cggttttcgt cggcaggcgc tagcgggtcc
    28141 agcccttcgc tcatcattcg ccatttcgcc gaccattctc cgcgctgacc attgagtaag
    28201 cccgtcatct ggcgcgacca gcttaaatag tcctgcgcca gcatcggcag gtcgagcaac
    28261 cattcgccgg gataatccac aatttccaga tacagcgtgg aggtatcctt aaagtggcgt
    28321 agcagcgaat cattcgattt aaaacgtagc gccaggcgga tttcactgac gccgcgcgtt
    28381 ggcgttggcc aggcgggtgg atcgccatat aactgcgcca gcccttcgtc ataggtgaag
    28441 cgcggaatgc caaagtcacg ctggggaatg cgtttcacgc ccagcaggcg ctcttcacgc
    28501 accgcactta acagcggcaa acgtgctccg gcgtgaatat taagcaactg attaaccatc
    28561 gcggtgataa acgctgtttt gccgctgcgg ctaagtccgg ttacagcgag gcgcagatgt
    28621 ctgtcgacac cccgattcac cagcgcattg agttcatttt taagtcgctt cattgctgtc
    28681 ctgtgctgct ctgaagacca gaaaaaaaat cattcgtaag gatatgaatg tgggggccag
    28741 gccattgatt atcaactgcc cgtgttgtca tcgaccggcg aactccataa gatgtgcagc
    28801 attcacgttc ggacggagtt cctgacctat gtcccctact atttatgata ttgccagggt
    28861 tgcaggcgta tcaaaatcca ccgtatcacg cgtgctgaat aagcaaacta atatctcccc
    28921 ggaagcgcgc gaaaaagtgt tacgggccat tgaagaatta cagtatcagc caaacaagct
    28981 ggcccgcgcg ctgacctctt cgggttttga tgccattatg gtgatttcta cccgttcgac
    29041 caaaactacg gcgggtaatc cgtttttctc tgaagttttg catgccatca ccgccaaagc
    29101 tgaagaagaa ggtttcgacg tgatattaca aacgtcgcac aatccggcag aagatctgca
    29161 aaaatgcgaa agcaaaatta agcagaaaat gattaaaggc attattatgc tcagttcgcc
    29221 agcggatgag tcattttttg cccaactcga taaatatgat attccggtgg tggtgattgg
    29281 caaagttgaa ggtcaatatg cccatgttta ttctgtcgat accgataatt ttggcgacag
    29341 cattgcgttg accgatgcat taattgaaag tgggcatcaa aatattgcct gcctgcatgc
    29401 tccgcttgat gtccatgttt cggttgatcg cgttaatggt tataagcaga gcctggctgc
    29461 gcataatatt gcagtgcgtg atgaatggat tgttgatggc ggttataccc atgaaactgc
    29521 attaaaagca gcacggcaat tattaagcca gtcaccgttg cctgaggcgg tgtttgccac
    29581 tgacagcctg aaattaatga gcatttatcg tgcggcagca gagaaaaaga ttgctattcc
    29641 gcagcagtta gcggtggtgg gttatagcaa tgaaacgctg tcatttattt taacgcctgc
    29701 accgggcggc atcgatgttc cgacgcagga gttaggtcaa caaagctgcg agttattatt
    29761 ccgcttaatt tctggaaaac cgtcaccaca gaatattacc gttgccacgc atatgacgct
    29821 gaaataaata ccagctacct tgcctgaatg ccagatgcga tgctagcgca tcttatccgg
    29881 cctacattta tagatcggat aaagtactcg cgccgcatcc ggcaatttag cccattatca
    29941 gaacgagtaa tttacgccga cacctgcata atggaattta tcactgtcgc cttcgtcgtg
    30001 atcctgccac tcaaacgcgt attccagcga aacggaaagt ccgttctgga aatcataacc
    30061 gtaaaataaa cctacacggt taaaatcatg gccttcacgt tcaatatcat cctgccagtc
    30121 ccagttactc cagcgatcca gcccaatgcg cgtatacggc gtcaccgagt ggttgccgag
    30181 cgtcagcggc aaataggcgc gaatttcttg cgtggaaaac tcaccgttat tgcggctgtc
    30241 gtccatattg aagccgcgct cgagataata gttcactcgc aaggcaaccg tttcgttgaa
    30301 ggtatattgc agacctgttt ccgtttcgac acgggtatca gcgtaaccgg tagtgttcag
    30361 atcgttggca aatttataca tcgacaacca accgttgaaa cgtaaatcgt cagtcagttt
    30421 cacatcccag tctggcgcga ttttccagcg ctgcatattc gccgtgtctt tacccggttc
    30481 atcaacgtag tgataaccat aattacggaa accgccggtc aggccgaaac tgaaatcatc
    30541 gttttcgagg aactgataat gcacctccag ctccgggcga tcaaaccacg ttccacgttt
    30601 acccgcgcta taatctaccg gcccttcctg ataataggcc agagcaattc tccacggccc
    30661 gttggcggca ttaaaataga ctgaaggctc cgccagccca tccatatctt cgccataacc
    30721 ctcgacgttt tctatttcgt acatcgcgcc gatattaaag tgccagtcgt tcctttcctc
    30781 ggcctgtgcg caggccattc ccgcacacat caccagtgcg gtacagggta ataacttttt
    30841 cattattgtt ccttgtatta tcctggggga atgccttccc cctgtattta gcgaattgct
    30901 atttccgttt ctgcatcaaa gaaatgacat ttcgtcatat caaaatgaat agtgatattt
    30961 tctcctgcat gataatcatt taacgcacca gcacggacca ctaactcgtg ccccccaacc
    31021 gtggtgtaga gcataaattc cgcaccggtt aattctgcca cgctaatttt ggcggaaatg
    31081 ttattttcct cttgcgcgtc cggatgaata tcttccggtc gtattcccat cacgatgggc
    31141 ttatgcaaac tttcctgtgt tttcagaacc gctaatttct cttcgggaat ggttaattta
    31201 agcgtttccg taacgaattt atcgccatcg atcgtgccgc gaataaaatt catcgctggt
    31261 gatccaataa atccggaaac aaacatattc gcgggttggt tataaacggt tttcggcgca
    31321 cctacttgct gaacaatccc gtctttcata atcacaatcc gcgtcgccat ggtcatcgct
    31381 tcggtctgat cgtgggtcac gtagatcatg gtggtgttca gtttctgatg cagcttgctg
    31441 atctctgcgc gcatttgcac gcgcagcttg gcatcaaggt tagagagcgg ttcatccatt
    31501 aaaaacacgc ccgcttcgcg tacaatcgcc cgcccaagcg ccactcgctg acgttgcccg
    31561 ccggaaagcg cccccggctt acgtttcagg tactcacgca ggccgagaat ttgcgccgcc
    31621 cagttcaccc gctcatcaat cacctctttg gcgatttttt gcatcttcag accaaacgcc
    31681 atgttgtcgt aaaccgtcat atgcggatac aacgcgtagt tctggaacac catcgctata
    31741 ttgcgtgctt tggctggaac gtcattcatt cgtttgccgt cgatcaacag atcgccgccg
    31801 ctgatctcct caagcccggc aatcatgcgc agggtggtcg acttaccgca gcccgacggg
    31861 ccgacaaaca cgatgaactc tttatcggca atttccaggt tgaagtcctt caccacatgc
    31921 acctggttat cgtagatttt ttgaatatgt tgtaacgaaa gctgagccat gttgattcct
    31981 ttgctatacg ttttgccaga aggccgataa ccgcggccag gtgagtgatt ccgttgaagg
    32041 caacagtaat tgcgccccgg ttaagcccgc gccgatcccc accgagcgca taccgctggc
    32101 gttaatggcg tcaatgcccg cctgcgcatc ttcaatgccg atacatgcct gcggcggcac
    32161 gcccagccct gcacaggcgg cgagaaagat ttccgggtcc ggtttcgagt ttttaagttg
    32221 ggaagcatcc gcgcagaagg tgaaaaactc gcgcagctcc agcgccgcta aaatcgtcgg
    32281 cgcattcagg gagacagaag ccagcccaac cgagatctgc tgtgcacgga gatctgccag
    32341 caaagagcga atgccgggta gaacagcgtt gaccgtcaac tcgcgtagtg agtggacata
    32401 gagcagattt ttgcgatacg ccagttgcgc cctctcctgc gagttaaagt cgccctcttt
    32461 gcccccgtgt tgcagaatgc gccgcagaga ctcatcgcgg ctgatccctt ttagggattc
    32521 gttaaactgc gcatcaatgc tgatgccaat ttcagcggca atctgctgcc acgcctggaa
    32581 atgcagatgc gcggtatcgg tgattacacc atccagatcg aaaattaccc cttgcagttt
    32641 cattcatcct cctgatgttt ggtagcggtc ccattgaagg gcaaaataaa atcacccaaa
    32701 cagaaaacag attcttcagc cacggttata agctgaccgt tcaaacgcag tgaaacgggc
    32761 gcagaagttc gaatcgcaat acgctgcgcg tcaagagtga cctgtaattc gcagccctgc
    32821 cagaacagag ggaaagacaa ctgttgccac tgctcaggta acgccggatt gagatgcaat
    32881 tcaccgtcac gcacgctcac cccggcaaaa ccctgaatcg cccccagcca gatagcgcca
    32941 gttgcggcag catggatacc atcatcacaa ctatgcggat cagcaccaag atcgatttca
    33001 gtcccctcgc gccagaactg ataactttgg gtcagcaggc cacagcgtgc ggcaacaatg
    33061 ccgtggattg ctttacttaa tgacgagtcg tgaatagtgc gcggttcata aaattgcaga
    33121 ttggcaagac acgatgccgc tgagaactgc tccggcagca tgtaattgag catcaccaca
    33181 tcagcttgtt tgaggatctg catctcgttc acttctgcgc gtgaataatc cagcagtatg
    33241 gtttgcttcc ccgccgccgc tttgtatttc gccagattaa tcgccggctt agccataaac
    33301 gaatcatcct gcggcaaaac gccgtcgggc tgaatttctg gcatccatag ctctttgagg
    33361 aacatttcgg cgcgatggat aaacgcatcg tcgctacagc cgaactggcg ggcaatattc
    33421 agcgcctgtt gaacgttgta gcgggccata tagctggtgt atgcattatt attgacatgt
    33481 tcggtatatt cgtctggccc aataacatca tgaatttcca gacgatcgtt aactctcacc
    33541 gcgcggctaa tccagaactt tgccgtctcc agaagtagcg ccatgccttc atgcgcaatg
    33601 aaactttcat cccccgtggt ctgccagtat tgaataaccg cccaggcgat atcggccacc
    33661 agatgatgtt ccgcctgcgc cgaggccact ttttgccgca gcccggtgcg aatgttaatg
    33721 gcggcaaatt ccggcgtctc ttcttcgccg ctgcgcgcgc tttcccacgg aaatagcgcg
    33781 ccctgccagc cgttgcgtcg cgctttctcc tgcgcgcctg gcaagttgtg ccagcgataa
    33841 cgcagtaaac ttcgggcaac cgtcggatcg ctaaacagat gaaacggtaa caaaaatact
    33901 tctgtatccc agaaaacgtg gcctttgtag ccttcgccgg ttaagccttt tgccgcaatg
    33961 ctgctgcgct cgtcgtgggc aggcgtcatg atgcgcagat gataaagcgc ataatctaac
    34021 gcttgctgat cgtgcgcttc gccgccattt accgtgatac gacgtttctg ccaccattga
    34081 cgccagtttt ctgttgatgc tgcaagaagt tggtcgtaac tctgctgcgc gcacatttca
    34141 agctggcgaa gcgacgcgct gccccactcg tctaaagcag cttgcctgtc atcccgccag
    34201 tcgatccaca ccagtttttg caacgtcatt gtctcgcctg catgaagctg cgcactggta
    34261 tgttgcagta aacggcgctc tttggcggta tagcattgct gcacatcacc gctcacctta
    34321 cagcaacagc tgatggccac atcactgcgt ccatcctggg tggtgtagct cccctgcatc
    34381 agatgctgac caaacacccg cacctgggtt tcgtcgagat gttggcgacc gtgattggtt
    34441 tgcgtggcgt caatgcctgt tgaaatcagc actgacgcgt cggcgtccag tggcgtaata
    34501 gtgatttcca gcgcaatgag cggcagttgg tctgccgaaa caaagcgacg gctggcgatg
    34561 gtgtaacctg agccgttgct ggtacgccag acaacattgc ggcgtaattc gccactggca
    34621 aagtcaagct cacgctgcca ggcttcgtgg gataacgaga aaacctcacc atttatggca
    34681 atctccatcc ccacgacatc aggcaggttc accagttcgt tgatttcacc ttttcccgcc
    34741 cgatgataca gccccgccag atacatccct cgcgtctggc gcgtgtaatc ttcttcatgg
    34801 ctggcgcgaa gcccaagata gccgttcccc tgcgccatca gcgatgcata cttgttcagg
    34861 gtatgctggc tgaaatgggg ttctgataac gttactggcc tggtcataat tccacacgcg
    34921 tccctgtttc tgcggattga tacaacgccg ccaccagttg ctggatgatg tacccctgct
    34981 cggcgtcggc tatcatcacg ggcttgccct gtacgtgatt gataaaggct tccatgctgc
    35041 gcaaatggcg gttgtcgtct gccatttccc gttgcatcag cgtcattaat tcaccgttgt
    35101 tatcggtgta gatatgtgct ggaaacagcg tcgcaccagc tttatcacca caaaagctga
    35161 cgttcataat cgactgttcg cggatgttga gtgcaaatga cgtttccagc cacagaatgc
    35221 cgccgttatg aaattcaatg gtgccaaaca gcgaatcttc gacgctgtaa gttgccggat
    35281 cccactcacc aaattgacca cagctctttt gcgtgccgat cttttgaaag ctatgcgcat
    35341 tcacgctttt caccgccgga aagcccagca catacatcgc agcatccagc atatgaatgc
    35401 cgatgtcgat cagcgggcca ccaccctgca gttctttatt ggtaaagaca ccccagccgg
    35461 gaacgccgca gcgacgcagg gcgcgggcgg tggtaacgta aatctctccc aaaacgccgt
    35521 tggtcacctg ttcacgcagc tgttgcgtat cgagcgcaaa acgatggtga aagtcgtagg
    35581 ccagcacctt gcccagtttg cgcgcggtat cgcacatttc ccgcgcctgt tctggcgtca
    35641 tggcgggcgg tttttcgcac atcacatggc agcccgcttc cagtgccatc agggtatgtt
    35701 cgtaatgaaa acggttaggt gagcagacgc taaccacatc aggtttcacc gccagcagca
    35761 tggcctgcgg atcgtcccac acggatgcat tcccgtattt ttctgccagc gcctgcgcct
    35821 gggaaaggcg gctgtcacag acagccacca gttccagatc gttgcgggtg cagtagtacg
    35881 aagcatgaac cttatccgcc acctggcctg cgcctattat cgcgacccgc agcggagagc
    35941 ttgtcattgc acttttcaca aagacctctt agcaggtacg caaccaggcc aacgaatcac
    36001 ggtacgcctg ggcaggatct tccgcccgga tacgcccttc gtacactaca tagccctgat
    36061 agttatccgc gcgcagctgt tcaaacagcg cgtggaaatc cagggtgccg ctgcccggct
    36121 ggtagcgatg gttatccgca atatgcacat gaccgagcag gtcgcggttg tcatgcagcg
    36181 cctgcgccag gttatcttct tcgatattca tgtgatagaa atcgccgata atctgtacat
    36241 gtttaagatc gttttcgacg atgtaacggc gggcatcggc gagggtgttg atcatatgat
    36301 cctgatagcg gtttaacggt tcgagataca ccacggttcc ggtacgcgcg gcgacctgtt
    36361 ccagtacgcg cagggaatca ctcaccattt tgcggtcgcc gtccaggcta cgcggcgagg
    36421 tcatcggcgg taagcggaag gtaaacatgc cccacgcagc cggaacgacg atgcctttac
    36481 cgcccacttc tgccagcgct tcgagaatgc gctcgatctg ctttaagcca ttaagacgac
    36541 gctcttcgat aaagtcgcca atccatccgt catagccacc gcaggcggtg gtcaccggta
    36601 aaccggtttc tttgatcgcc gctttgactt cttcgatgtt gttaaccagc agtttgccgt
    36661 caatctcaaa accatcgaag cccatctctt tgatataacg aaatttctcc agaatgtttt
    36721 ccggaaagaa cgcctgattc tgtgtgccga ttttcatttt tttcattcct ttgaattaaa
    36781 acgtaacgcc cattttgatg ctctgttccg gatgctggtc gacatactgc atatagcttt
    36841 ccgggctatt ggcaaaggtc accaccgggt cgattaaatc ttcgcaattg agataaccgt
    36901 tcatcagcag ttcccaacag gtttcttcaa tacgcttgcg gctccagcgc ggataatccg
    36961 ggttcggttc gctgcacgcg cgagagaaga caattttggc gttattgaaa tgcgcttcgc
    37021 gtccgaggtt aaaaccttcg gcaaacggct tggcaaacgc gacataggag atggtgccgc
    37081 cataagccag accgcggagc gccgattgca gcgcgtcggc gtagccgctg gtttcgataa
    37141 tcacatcggc accctgcttg ccggtcagcg ttttgatctc tttacctaca tcagtgccga
    37201 tggggttaag gcagaaatcc gcgccgtggc gacgggcaat atcacagcga tgggcgatag
    37261 gatcgacgcc aatcaccaca gaagcgccag cgcgtttagc cagttggatg gcaatttgac
    37321 cgattgcgcc aagccctacc accaccacaa aatcccctac gcgcacgttg gcatcgcgca
    37381 cgccgctcat ggcaaactgc gccgggtcgt agcagacggc gtttttccag gagctgcctt
    37441 gcggcatttt gcgcagcttg tagttattca ctgcgttaat gatgaccgtc tcggagagcg
    37501 ggccgtagcc gcatacgctg tcgcccaccg cgtagtcggt aacgtcgctg ccgcactcga
    37561 taatgtcgcc aaccaccatg ttgccaagct ggaatttgcc aaactcaatg ccgcgcggcg
    37621 catctgccgg acgcggagtg aacatctgcc attcgccgtt aaagtcttca tcaataaacg
    37681 ggctggcggc gcggaagtcg accacttccg ttccgtgttt cggtgcgccg aaacgcacgc
    37741 ggatcttcac ttcattagct aaaatcgccc gatcttcata ctcaaccagc gcagcaacac
    37801 gcggtgctgt ggctactaac tttttcattt aaaactcctt gtaaagaaac tggccgcttt
    37861 agcccttcac gccaccggcg gtcaaaccac tcttaataaa acgttccgaa agcgcataca
    37921 taatcaccac cggcaatgcg gtcaccagtg aggccgccat catccgtccc cagatgtaat
    37981 ctggcgtact gaacagcgcg ttcaggccca ccggtaaggt gaaattgctg gcgctggaga
    38041 ggaaaatcga cgcaaacaga tagtcgttcc acgccaccat aaagcagtag acgaacacgg
    38101 atatcagccc ggacatcgcc aacggcacgg tgatgcggaa gataatttgc agacggttga
    38161 ggccatccat catcgccgct tcttcgatct catcggggat ggtgtcgaag tagcttttca
    38221 gcataaacac ggcggtgggc agagtttgcg tcaccatggt gatgatcagc gccatctcag
    38281 tgtcgtaaat gccaagcgcg gtgatgattt tgaaaagcgg caccaccagc aaaatgccag
    38341 agaacatata caccgtgtaa aagctggcgt tgatggtcat ccgaccttta aagcgcaggc
    38401 gggaaagcgc gtaagcccca agaatgccga ggaataccgc caccacggat gaaaccacag
    38461 acaccaccag actgttacgg aagtagtcga caaacgggaa aatcatcggg ttaaaaatgt
    38521 cgacgtaatg ctccagcgtc cactgctgcg gcagcagcgt aggatgcagt gagatcgcct
    38581 ctttcgcgcc cttgaacgag gtcatcagca tcacaaaaaa tggaaacagc gtgatgatga
    38641 gaaacagcgc cagcccgcag taaaaaccga tgcgactgag tgtgcgttta tttgttgcca
    38701 ttgaggttca cccgtttcct ggtcagcaga atgacagcga aaataatgat gaagagcacc
    38761 accgagatcg ccgccgcttt tcctaaatca ttaaaggcaa aggcggtttt gtagagatat
    38821 acaccgagaa tatcgacctt ggtcgtcagc aaataaacat ccgcgaacat gtagaacatc
    38881 cagatggtgc gcagtgtcac caccgtcgcc aggaccggca taattgcggg cagcgtgacg
    38941 atacgaaacc gttgccaggc attagcgcca tccatctctg ccgcttcgta cagcgatttg
    39001 tcgatggtct gcaaaatcgc cagaaacgag ataaaggcat acgggaagta gcgccagatg
    39061 gcgaacagca ccaccagcac aaagctactg cccggattat cgaaccacag cggtgcctgc
    39121 tcatagagat gcagaagatc gacgccgagg tagttaacaa tgccgtagcc gttgttgaac
    39181 atgtatttcc aggcgaacac cagcgaaatg gacggcgtta cgtaggagag gatcaccagc
    39241 gaacgcgcgg ttttgcgcag gcggaactcg cggttgaaaa acatcgccac cgccagcccg
    39301 agcacggtgc tgcccgccac caccagcgcg gtataccaga ccgtcatcca cagcgaatgc
    39361 cagaagccgg gatcggagag gatacgcaca tagttgctca ccccaacaaa cgttgactcg
    39421 atgttgggat tgagcggcag acgtaaaaaa ctgatttcga tattcgacac catcggccac
    39481 gccaccagac cgcccagcag taataagctg ggcgcgagaa gcagcagcgc aaagggcata
    39541 tcggaacgac ctgaaaaaag cctgttcatt gcggattcct gtcctgggtt tagtgctgtt
    39601 cgatcagttc atccagtttt ttctggctcg cttgcagcgt agtagagaga tcggctttac
    39661 ccacggtgac gttatgcacc attgaactca ccacgccaga acccgtcaca tcacccatgc
    39721 gggtaaagtt tttatcccct actgcgccaa aaacctgaat atttggcagt tcaccgatta
    39781 gctgattcgg tagttcaccc agcgccttaa taacgtcgtt gtctttccag gtggcggtag
    39841 tcaccaccgc tttattcacc ggcagcgcag cacctggcga catcatcacc cagtcggcaa
    39901 tgttgtctgc ctgctccata aaggtgacaa atttttctgc tgcttccgtc tcttcggtct
    39961 tttgcccggc ggtaatggtc agcgaggtca acatgccgta gaccgcagag tttttctcgg
    40021 ttggcaccac gaaaccgacg tttttcgggt cgccttcttt aatcacagcc ggaaggatat
    40081 aggtggagta aatcgccatc ggcgcggtgc cgttcataaa ggcgtctttc acttccatga
    40141 tgtcgttaga acccggcata gtgttggcag caaggtcgcg gtaataggtc agtgcctgca
    40201 tcatctctgg tgtatcaagg gtgattttgc cttcggcgtt aaagacgtta gcctggttgg
    40261 ataacgcaaa ctgggagaag gattgttccg tcaacacgct ttctgctgta ggcagcgcaa
    40321 tgccgtattt tttattcgcc gggtcattca gtttctgtgc aacgtccagc agctgttgcc
    40381 agtttttcgg ctcctcaagc cccgcttttg ccagcacatc tttgcgatac cagataccgc
    40441 caatccaggc gctgacagga acaccggtcc atgcgctacc atcttcggta cgcacaatac
    40501 gcagtacgcc atcgtaaaac gcgccttcac caacgttgct gatgactgtg gcaaccgctt
    40561 tgcgatcgat aagctgctct ttgtccatca ctttggcgta gtcatggctg gtttcgatca
    40621 cttccggcag cgaaccgcta cgtgaaagag taatgacttt agtgttatag gcatcttctt
    40681 ccacgggcac ttgcttaacg gtgatgccag ggttttcttt ttcaaaacgg gcaatcaatt
    40741 tactgataac ggcctggcgc tcctgctcca ccgaagaatg cataaattcg atggatacat
    40801 tcgttttatt ttcttcttta cagcctgaaa tcagggcgca tgaaaccagt gctgataaca
    40861 gcacgatttt tgatttaatc atgagatgtt cctttttatt taatccacat aacctgccag
    40921 gggcgcagcg ttatttcatt acccaatata tcaacttcac taatcagatc ccgaccatgc
    40981 agattagtaa tatttacatg ctgaatattt ttactgacat taaacaatcc agtcagacaa
    41041 ttaccatcag cgttacttct ttgaatacgc attacggatg aattaatcgt atcaatggta
    41101 aaattattat ccggatgaaa ctcgttatgg ctgcgacgaa gtgtaattaa acgcgacaac
    41161 tcatgatata ccgcatgcct taatgtagct tcatcgttca gttctcgggt tatctcttta
    41221 ctgtgatatt ttttacggtt aatcgcacgg ttatatccga gtttttcgac acctgcgtaa
    41281 tcattacgcg agccaagaat actttgaata tatatcgctg gcacaccggg gaaacttaac
    41341 aaaatcgcat gggcaaggat aaacctggcg caacgttctt catcgctact ctcacggcgg
    41401 cttaacgcat ccatataggt cacatttatt tcatacggac tgcgtgtacc gtcgggatta
    41461 tttttccagt ttactaatgc accttcctgc tgtaacgcct cgaccagctc taatatttcg
    41521 ctttcaggca acaagccccg tagcgggttt agcccgatgc catcgtgaga ggcgaggaag
    41581 ttaaaccagg tggtgttgct ggaaggtagt gtcaggtttt gcgcccacgc acaaagcgcc
    41641 tcaacgttct gtttttgcac cgcatgcagc accagtggcg gcagcgagaa ctggtacacc
    41701 atatgtgctt cgtcatcgcc tgcgccaaag taagcaatgt tgtctttatg cggaacattg
    41761 gtctcggtaa tgatcactgt acctggcgca acgttatcaa taatcgaccg taacagtttg
    41821 ataatcagat gtgttttttc cagatggatg cagcttgttc ccggctcttt ccacataaag
    41881 ccaacggcat ccaggcggac atactcagca cctttcgcaa ggtaacagag taaaacatcc
    41941 accatcgcca gcaacacttc agggctacgg taattcaggt caatttgatc gtcactaaag
    42001 gtggtccata aatggcgcgt tgaatgatcg cgcatctgga atggcgttaa taacggtaac
    42061 gcacgcgggc gagtgacggc gctgagatcg gtttgcgggt caacggcaat aaaaaaatct
    42121 tcaaaacctg gatgctgttg taaatagttt ttaaaccatt cactttttgc cgacatatgg
    42181 ttgcagacaa aatcaaacat taaatgactg cattcaccga gttgctgaat atcctgccac
    42241 tcccccgctt cactggcgac ctgatgataa tcaattaccg aaaagccatc atcagatgac
    42301 catggataaa acggcaacaa atgaacatgt gaaaaaatgc tttgcagcca ttgatggtaa
    42361 aactgattaa atgtgggtaa tggttttaaa tcattgctgt gaaattgatc ggcataggta
    42421 attaacacga catcactttc atcccagtgt tttttacgtc gctgtgtaat taatcgtttc
    42481 gcactctcaa gacgcgttac aagtttctgt aaatgagttg cggtaaatgt tccaccgtag
    42541 atttcgtcca ggtaatccgt aattttctgt ttcatgttgc ctttccgtgg tagcggtccc
    42601 atgaaacgag agactactcc gcagaaaata aactgtcaat tgagcacaag ggttttagtc
    42661 acgcaggaaa tcatttttta ccagggaaaa agcgtatttg tgagctgacg caaataatct
    42721 atggggatgt aaataaggtg tgacagaaaa aaaaacggcg cataagcgcc gctcatggtg
    42781 aattctttta acctttgacc ttcggcattg cgatgtcttt caggccaccg gcgttctcaa
    42841 cgtgggtata tcccatctcg ctaaggatct cttttgcttg ccctgactgg cgtccggcat
    42901 tgcaatacac tttcacggtg tcgtttttat ccggaacggc ggtggcaatg cgctctttca
    42961 cttccttcag gggaatattg atggccccct gaacgtgctc ttgctgatac tgctctggaa
    43021 cacgaacatc gatccagtgt tcagcggcga aaacgggcag tgaaaacacc agtgccagag
    43081 caagtaagcc ttttttaaac atgtaagcgt ccttctatgg atgaaaattg ccatccatta
    43141 tacgcctgag atttaacaat ttttgcgaaa ctcccctcac cttttataac gctgtgccag
    43201 tttattagca gcccgactta acagcggttc cagcgccaca gccagcaaca ttttcagcgg
    43261 tcggcgagca actgatttta tcgcccagcc cgccacaccc gccgggccat agcgcagtgc
    43321 ggtaagaagt accagcttgc ctgctaattt gaaaccaggc tttacctttt gcccggcctg
    43381 ttgccagcga gtattcataa ctttcctcac agttgacgga aacggctacg taacgtgaaa
    43441 gtatcggaag tgacataacg ttccatctcg cgtaaacgcg tttcacttgc cgccagttca
    43501 cggtcgactt catccagcaa ttcgctgctg gaaggtagct gctcaccaaa ggccatgttg
    43561 tccggcattg gatcaagcgc aaatgacaaa atgatgtaag caaccagggt aaacagcgcc
    43621 agaccgaaga aaatcgacag caccaccagg atacgcacca gttttaccgg tacatcaaaa
    43681 tagttggcaa tcccggcgca gacgccgcgg accatgccct gctgtggaat acgccataat
    43741 tttttattga gattaatgcc cgccattagc gatccctcca gttcggatgt tctgcatcaa
    43801 gaatagattc cagcgcctga atacgttcgc gcatccgttt tgcttcatca gccagttgcg
    43861 ctaatcgctg ctgctcactt tgcgacaatt cactgcgacc agaacgattg ctgtaatgca
    43921 gccataacca gatcggtaaa acaaacagca caaaaatggt taacggaata gccagaaata
    43981 gcgcgctcat aagtactcct tagacgatga gcggcggcgc gttcggacgc cgcctggatg
    44041 ttattattga ttgtcttgct tcattttggc ttttaattgt gccagttgtt cgctgattgc
    44101 atcatcggct ttcagttcgg caaactgatc gtccagcgat ttttgtttac cgaagctgtg
    44161 gctttctgct tccacttcca tctggtcaat acgacgttcg aaagattcga aacgagccat
    44221 tgcttcatcc agtttgccac tgtccagctg acgacgcaca tcgcgcgacg agtttgccgc
    44281 ctgatgacgt aacatcaatg cctgctggcg agcgcgtgtt tcgctcaatt tgttttccag
    44341 ctcgccaatc tctttcttca tgcgtgccag cgtatcgtcc accagcgtca cttcatgttc
    44401 cagggactta atcagatcgg tcagtttctg tttttcaatt aacgctgcac gtgccagatc
    44461 ctctctctct ttcagcagcg ccagttcggc tttttcctgc cattcaacct cacgcgccga
    44521 cgcttgttca atacggcgag tcagctgttt cttttctgcc aacgcgcgcg ccgaagtaga
    44581 acgtacttca accagtgtat cttccatctc ctggatcatc agacgaacca gtttctgtgg
    44641 atcttccgct ttctctaaca gagcgttgat gttggcattc acgatgtcgg caaagcgaga
    44701 aaaaataccc ataatgttgt cctcttgatt tctgcgttca ggattgtcct gctgaactgt
    44761 taatacaatt tgcgtgccaa ttttttatct ttttgattta taaagatctg attgaagaat
    44821 caacagcaac atgccaggat gagttagcga attacactaa caagtggcga atttcatcat
    44881 ggcagaatac aaagataatt tacttggtga ggcgaacagc tttctcgaag tgctggaaca
    44941 ggtttcgcat ctcgcaccgc tggacaaacc ggtgctcatc atcggcgaac gcggcaccgg
    45001 taaagagctg attgccagcc gcctgcatta tctctcctcc cgttggcaag ggccgtttat
    45061 ttcccttaac tgcgcggcgt taaatgaaaa tctgctggat tccgaactgt ttggtcacga
    45121 agcgggggcg tttaccggtg cgcaaaaacg tcatccaggg agatttgaac gtgccgacgg
    45181 cggtacgcta tttcttgatg aactcgctac ggcaccgatg atggtgcagg agaaattatt
    45241 gcgcgtgatt gagtacggtg aactggagcg cgttggcggc agccagccat tgcaggtgaa
    45301 tgtgcggttg gtatgcgcga cgaatgccga tctcccggcg atggtcaatg aaggcacttt
    45361 tcgcgctgac ctgctcgacc gactggcttt tgatgttgta caactgccac cactgcgcga
    45421 gcgcgaaagc gacataatgt tgatggcaga atactttgcc atccagatgt gtcgggaaat
    45481 caagctgcct ctgttcccgg ggtttacgga gcgcgccaga gaaacattgc tgaattatcg
    45541 ttggccggga aatattcgtg aattgaaaaa cgtggtggaa cgttcagtgt atcgccacgg
    45601 caccagcgat tatccgcttg atgacatcat tattgatccc tttaaacggc gtccgcctga
    45661 agacgctatc gccgtttcag aaaccacctc gcttccaaca ctgccgctgg atttacgtga
    45721 gtttcagatg cagcaggaaa aagagttgct gcaactcagt ttgcaacaag ggaaatataa
    45781 ccagaagcgc gcggctgaat tactggggtt aacttatcat cagttccgcg cgttgttgaa
    45841 aaagcaccag atttagcgaa gttgagcaat acaacttgcc ggatgcggcg tgaatgcttt
    45901 attcggcata cataatcaat acgtcgtttg caggcctgat aagcgcagcg catcagacat
    45961 tattgcgttg ggctattaat cgctcagcgc atcctgcaaa attttcattg ccgcatcgaa
    46021 ttgcgcatcc gggatggtca gcggatacag gaagcgaatc acgttgccgt atgcgccaca
    46081 ggtcagcagg agcagcccct gcgccagcgc gcgttgctgg attttctgtg caatcgccgc
    46141 tgacggctcg cccgtttgcg gatcgttaaa ctctaccgca atcatcgacc ccaggccgcg
    46201 taccgcagca atggccggaa cgctttcttt ggcatcaatc aacgtgtttt tgagacgctg
    46261 gcccagttga ttcgcgcgtt cgcagagtga ttctttgtcg ataatgttga gcaccgcgtg
    46321 cgcggcagcc accgccagcg ggttaccggc gtaggtgccg ccaagcccgc ccggcgcggg
    46381 tgcgtccata atattcgcgt taccgaccac gcccgaaagc ggcatcccgc ccgcgaggct
    46441 tttcgccatc gtcattaaat ccggcttatc ggcgtaatga tccatggcaa acagcttacc
    46501 ggtacgcgca aagccgcttt gcacttcatc agcaatcatc acaataccgt gctcgtcgca
    46561 caggcggcga atagcggcaa ccagctcttt tggcgcaacg ttgaaaccgc cctcgccctg
    46621 caccggttcg aaaataatcg ccgccacctg cttcgcttcg atgtctgatt taaacaagcg
    46681 ttcgatggcg tcgagggagt cctgtgttga aatgccgtgt aaatctgacg gataaggtac
    46741 gtgatacacc gaaccaggga acgggccgaa gccgattttg tacggcgcaa cttttccggt
    46801 cagcgccatg gtcatatacg tacgaccgtg aaagccgccg ctaaacgcaa tcacgccagg
    46861 gcgtccggta tgggcgcgag caattttcac cgcgttttcc accgcttccg caccggtggt
    46921 gaagaacgcg gttttggcct gcccgctcac cggggcaagg gcgttgattt tctccgccag
    46981 ggtgacgtag ctttcatacg gcacaatctg atacgcggtg tgggtaaact gttgcagttg
    47041 ctgctccacc gccgcgacca gatcagggtg gcgatgtccg gtattcagca ccgcaatgcc
    47101 tgcggcgaaa tcgatgtact cgttgccctc aacatccttc agcgtggcgt tttcagccga
    47161 ctgggcgaag aagttacaca tcacgccaac cccgcgcgga gtggcagaaa gacgacgctg
    47221 atggaattca ttgttgctca tgtttcacac cttttgactc ttcacggtta atcggaaatt
    47281 aaacgcccag acgatcgcgc aggctgtaat acgccgcgcc catcgcggta aacggcacac
    47341 gcagcgtgcg cccgccgggg aacgggtaat gcggcagatt ggcgaaggca tcgaaacgtt
    47401 cggcgtcgcc gcgcagcagt tcggcaatca aacgtccggc tagatgagta caggtcacgc
    47461 cgtggccgct gtagccctgc atgtaataga tgttggtatc gaggcgacca aactgcggca
    47521 tacgcgacag ggtcagcagg aagttgcccg tccagcggta atcaattttc acgcccttca
    47581 gctgcgggaa ggttttcagc agtttcggca ccacaaggcg ctcaacgtca tccgggtcgc
    47641 gcgcgccgta gaccacgccg ccgccgtaca gcaggcggtt gtcggcggta agacggtagt
    47701 aatcaagcag atagttacag tcttccacac agtagttttt cgggatcagc gaacgggcta
    47761 aatcttccga cagccgttcg gtggtgatca cctgcgtgcc gcacggcatg ctgcgtttcg
    47821 ccagttccgg ctctacttta tcgcccagat acgcattccc ggcgacaatc acatacttcg
    47881 ccgtcacctg acctttggca gttcgcacaa cggctggcgt ggtgtgctgg atctgcgtca
    47941 cggcagaaag ttcatacacg cgcccgccgt tgaggcggat ggcgtccgct tcgccaatgg
    48001 caaggtttag cggatgaata tgcccaccgc tgtgatccag cagcgcaccg gtatagcgat
    48061 cgctggctac ttcacggcga atggcgttgg cgtccagcaa ttccagctgt ttattgccgt
    48121 agcgttccca gttctctttc tgctcttcaa gtgtggcgag ctgtttatca ttcatcgcca
    48181 caaacaggcc gccggggcgg tagtcgcagt caatctgata acgtttgata cgttcgcgga
    48241 tgatctcacc accttcgaac atcatgctgc cgagcatacg ggcggtgtcc atgccgtagc
    48301 ttttttcgat cacgtcgatg tcgcggctgt aggagttcac aagctgtccg ccattgcgcc
    48361 cgcttgcgcc aaagccgatg cgtgaggctt cgagaaccac tacgtcaaag cccgcttccg
    48421 ccagatgcag cgcggaggag agcccggtat agccgccgcc aaccacgcaa acgtcgcagg
    48481 tgattgactc attcagcgtg tcgaatggtg catatttatt cgcactggcg gcgtagtaac
    48541 tgctggtatg ttcggtcatt tcaggcctcc aggcttatcc agatggtttt cagttcagtg
    48601 aatttttcaa gggcatgcag ggatttgtcg cgaccgttgc cgctctgctt atagccgcca
    48661 aacggcacgg tcatatcgcc gtcgttgtag ttattgacga agacggaacc ggctttcagg
    48721 cgtcggctca tgcggtgcgc gcgggagagg tcgcgcgtcc ataccgccgc gccaaggccg
    48781 tactggctgt cgttggcaag ctgtagcgcc tgttcttctg atgtgaaacg cgtgaccacc
    48841 agcaccggac cgaaaatctc ttcgcgactt aaggacgcat tcgggtccac atccacaaag
    48901 atggtcgggc cgatggcggc agccagcccg gcgttacggc catccaacaa cagttgccct
    48961 ttgctttcgc cttcccgaat aaagctatgg accgagtcgg cgtgggcgca gtcgattaag
    49021 gtgcccatgg tggttgcggg atcaagtgga tggcccggct gccagttttg cgcctgctgt
    49081 tttaacaggg ctaagaattc atcggcgatg ctctcttcca gcaacaggcg cgttccggcg
    49141 atgcacacct gtccctggtt gtagaaaatg cctgctgcgg tggcgcttgc cgcctgttgc
    49201 aaatccgggc agtcagcgaa aacgatgttg gcgcttttgc cgcccgcttc cagccagacg
    49261 cgtttcatgt tgctgtcgcc cgcatctttc agcagctgtt tcccggtacg ggttgaaccg
    49321 gtaaaggcaa tggcgtcgat atcgttatga cgcgacagcg cctgcccggc ttcatgacca
    49381 aaacccgtca ccacgttcaa cacaccatcc ggcaagcctg cttctttcgc cagccccgcg
    49441 agacgaatcg cactgagcgg tgatttttca gacggtttta gaatcacgct gtttcccgcc
    49501 gccagcgccg ggccgagttt ccagcaagtc agcaacagcg ggaagttcca cggcacgatg
    49561 gcggcaatca cgccgaccgg ttcacgcacg atcatcgcca gctcatggct actggtggtc
    49621 gccacttcgc catacacttt gtcgatcgct tcggcgtacc agcgaatggc gcgcgccgcg
    49681 ccgggaatat catcacgcag actgtgacga atcggtttgc cggtgtcgag agtttccagc
    49741 agtgccagct cttcggcgtg ggcttccatt aaatcggcga gtttattcag taccgcttta
    49801 cgtttagccg gagaagagag tgaccagtcg ccgcgttcaa atacgccgcg tgctgcgctc
    49861 atcgcacggt cgatatcgac gctcttgccg cgggcaattt tcgccagcgg tgcctgggtg
    49921 accggatcaa cggtttcaaa ggtttcattt tccgccgcag cagtatattc accgttaata
    49981 aataagcggt tttcaatggc gagacttaac gctttatcct gccagtaagc cagatgatga
    50041 aaattcatta tgactcctgt ttcacgtcta tcagatatat gcagtttgtg aacgtcaggg
    50101 cgcagagatc cccgggccgt atgcccgttt atttctggcg acattcttta tatacacttc
    50161 atccttcaag ccgcctctgc cttggctgcg ttcgctcccc cgaatcactt acctgagtaa
    50221 gctcatcggg attcgctcac ttgccgcctt gatgcaactt gaatgatttt gtgtatagat
    50281 tgccgggcgc attgcgctta cccggcttac agaacaaaaa gattaaaacg tggtgggcgt
    50341 atgggcgctg ataattcggc aaatacctgc cgacgtatta ctgaaactgt gcgggatgcc
    50401 ggtattaatg gcataacttt gccccgcgac gaggtggtaa tcctgaccat taatcgtcag
    50461 aacaatttca ccttccagta cagtgcctat ttcctcaccc tgatgcttaa ttctttcccc
    50521 agtggttgtg cccggctggt acgtttcaaa gatcatcgcc agcgtgcgat tcgggttacc
    50581 gttatgaacc agcttcattg acacaccctg actacccatc tcaattaagt cgtcctgatt
    50641 aatgacgacc tgcggctcat caggtttttc cggctcggaa aagaattccg agagtgacag
    50701 accatacacc ttcagcagct tttgcagcgt actgatggca gggctgactt tatcttgttc
    50761 tatcgtactg atagcactgt gagtcagccc ggagagttcg gcggcacgac gttgtgaaag
    50821 cccctgctgc tggcggattt ccgacaagcg ttttcctggc gccagtccct catcactcat
    50881 atttgcattt ccttaaactg tagtggtcag agtcgctgtt tttcagcgat atggtgctga
    50941 caagcggtga taaagccctc gaacaatata cgcgaaagcg cgtactcgct actgttccat
    51001 tccgggtgcc actgtacgcc cagcgcaaaa ggatgattga tgacgctaac cgcctcaact
    51061 aagccatccg gcgagcgagc ttcaacacgc aaccgtgggc taacgacctt cgccccttgt
    51121 ccatgtagag agtttaccca aaagttgcta cattcaggta acaacgcaga cagtaatccc
    51181 ccctcttcaa cctgaacttc atgcgacggt gcatattgct gttccaccgg cagttcggga
    51241 tcttcccgat gttccagcaa ttcaggctgt tcgcacagct tgcgatgcaa cgaaccaccg
    51301 gttgccacca ccagttcttg taaaccccgg cagatggcga aaatggggat gcgcctttcg
    51361 agtgcggcat taattatcgc catgctcaga agatcacgcc cgggatcggc gtcaggctca
    51421 tcgccgtttt caccatatag gtgcggctgc acattgctgg gactaccagg aagataaatg
    51481 ccatcgagtt tcggcaaaag ttgttcaagt aatgacggtt ccgccagcgc atgtggtagc
    51541 gcaataggca agccgcctgc atggatgatg gcattcaggt acttttcttg cagagtctgg
    51601 gtcgcatgac ccttaagcct gttcctgcac attacgacac cgataaccgg attgttcatt
    51661 atattttcca tgctcaatct cacaaagtgg actaaattat cgccattact gcgctttaaa
    51721 tgacctttat gttcaatatt ttttcaatct agcagtgggt tttcattttt gcaaactcaa
    51781 tttaacattt gacaaacatt tagtttgcat acagattcga atggtggtca ttatatttta
    51841 cgctttgata acgagcggaa aacaaaccaa aggcgaagaa tcatggaaac caatatcgtt
    51901 gaagtagaga actttgttca gcagtcagaa gagaggcggg gtagcgcctt tacgcaggaa
    51961 gtgaaacgct acctggagcg ctacccgaat acgcaatatg ttgatgtttt acttaccgat
    52021 ttaaatggtt gcttccgtgg aaagcgtatt cctgtttcaa gcctgaagaa gctcgagaaa
    52081 gggtgttatt tcccggcctc ggtatttgca atggatattc tgggcaacgt agtagaagaa
    52141 gcaggtctgg gtcaggaaat gggcgagccg gatcgtacct gtgttcctgt tctcggttcc
    52201 ttaactcctt ctgccgccga tccagagttt atcggtcaga tgctcctgac catggtcgat
    52261 gaagatggcg ctccctttga cgttgagccg cggaacgttc ttaaccgcct gtggcagcag
    52321 ctgcgccagc gcggattgtt cccggtcgta gcggtagagc tggagttcta tttactggat
    52381 cgccagcgcg acgctgaagg gtatctgcaa ccgccctgcg cgcctggcac cgatgaccgc
    52441 aatacacaaa gccaggttta ctccgttgat aacctcaacc acttcgccga cgtgctcaat
    52501 gatattgatg aactggcgca gttacagctg attccggcag atggcgcggt cgctgaggcc
    52561 tcgccgggtc agtttgaaat caacctttac catactgata acgtgctgga agcctgcgat
    52621 gatgcgctgg cactaaaacg cctggtgcgt ctgatggcag aaaagcataa gatgcacgcc
    52681 acttttatgg cgaagccgta tgaagagcac gcgggcagcg gaatgcatat ccatatcagt
    52741 atgcaaaata atcgtggcga gaacgtgctt tctgacgcgg aaggcgaaga ttcgccgctg
    52801 ctgaaaaaga tgctcgccgg gatgattgac ctgatgccgt cgtcgatggc gttgctggca
    52861 ccaaacgtga actcgtatcg ccgcttccag ccgggaatgt atgtgccgac gcaggcgtcg
    52921 tggggccata acaaccgcac cgtcgccctg cgtattccgt gcggcgaccg tcataatcac
    52981 cgcgtggaat atcgcgtggc gggtgccgat gccaacccat atctggtgat ggcagcgatt
    53041 tttgccggta ttttgcatgg ccttgataac gagctgccgt tgcaggaaga agtcgaaggc
    53101 aacgggctgg aacaggaagg cttacccttt ccgattcgcc agagcgatgc cctgggtgag
    53161 tttatcgaga atgatcacct gcgccgctat ttaggcgaac gcttctgcca tgtctatcac
    53221 gcctgtaaaa atgatgagct gttgcagttt gagcgcctca tcacagaaac agaaattgag
    53281 tggatgttga aaaacgcgta ataccccttg cggggttgtt tcatcggcct gagcggagcc
    53341 aggcctgaca tttgctggta atccagacat ttcccggatg tcgcgttatg gagcgcgggc
    53401 ggcaacgggc ttccgttaac gattaagact gtgacgagga aatgagatga tgccgatgat
    53461 taaatccccg catggcgagg gaggctgcgt atgcgcccct cctgctactg actggactcc
    53521 gccccctttg cttcccttgc taaacaggtt tgatttcagg tcgacacgac cgcaaacctt
    53581 attacgcagg ggaggcagca attatggcta ttaattcacc actgaatatt gctgcgcaac
    53641 ccggcaaaac ccgtctgcga aaatcactga aattgtggca ggtggtgatg atgggtctgg
    53701 cctatctcac gccgatgacc gtatttgata cttttggtat tgtctccggc attagcgacg
    53761 gtcacgttcc ggcgtcctat ttgctggcgc tggcgggtgt gctgtttacc gctatcagct
    53821 acggcaaact ggttcgccag tttccggagg ccggttcggc ctatacctac gcgcaaaagt
    53881 cgattaaccc gcacgtcgga tttatggtcg gctggtcatc gctgctggat tatctctttt
    53941 tgccgatgat taacgtcttg ttggcgaaaa tctatctctc cgccctcttc ccggaagtgc
    54001 cgccgtgggt gtgggtggta accttcgtcg ccattttaac cgccgcgaat ctgaagagcg
    54061 tcaacctggt cgctaacttc aataccctgt ttgtactggt gcaaatctcc atcatggtgg
    54121 tgtttatctt cctggtagtt cagggactgc ataaaggaga aggcgttggc accgtctggt
    54181 cacttcagcc gtttatcagc gagaacgcgc acctgatccc gattattacc ggggcgacga
    54241 ttgtctgttt ctccttcctc ggtttcgatg cggtgaccac gctttcggaa gagacgccgg
    54301 acgccgcacg cgtgatcccg aaagccatct tcctgacggc ggtctacggt ggcgttatct
    54361 ttatcgcggc gtcgttcttt atgcagctgt tctttcccga tatcagccgc tttaaagatc
    54421 cggatgccgc actgcctgaa attgcgctgt acgtcggcgg caagctcttc cagtcgattt
    54481 tcctctgcac cacgtttgtg aacaccttag cctctggcct ggcttcacat gccagcgtgt
    54541 cgcgtctgct gtatgtgatg gggcgtgaca atgtgtttcc ggagcgcgtg tttggctatg
    54601 tgcacccaaa atggcggact ccggcactca acgtcattat ggtcgggatt gtcgcgttgt
    54661 cggcgctgtt cttcgattta gttaccgcca cagcgttaat taacttcggt gctctggtgg
    54721 cgtttacctt cgtgaatctg tcggtgttta atcatttctg gcggcgtaaa ggaatgaata
    54781 aaagctggaa ggatcacttc cactatttgc tgatgccgct ggttggcgcg ctgacggtgg
    54841 gtgtgctgtg ggttaacctc gagtcaacgt cactgacact cggtctggta tgggcttcgt
    54901 taggcggcgc atatttatgg tatctgatcc gccgctatcg caaagtgccg ttgtatgatg
    54961 gtgacagaac gccggtgagt gaaacgtaat agtcggatgc gcggcgcatt atcctgcctg
    55021 agggtaacgc gccgcgccat taactataaa aagatgtatg acccggatca cgagtgctat
    55081 catccgccct tatgcttagc gcattaaccc caggggcaaa taatgaacca cgatatcccg
    55141 ctaaaatatt ttgatattgc cgatgagtac gcgaccgaat gcgcagagcc tgtcgcagag
    55201 gctgaacgca caccgctggc ccactacttc cagttactgc tcacccgttt gatgaacaat
    55261 gaagagatca gcgaagaagc ccaacatgaa atggctgctg aagcggggat taatcccgta
    55321 cgcattgatg agatcgcaga gtttttgaat caatggggta atgagtaatg atttaattgc
    55381 agacgatcgg tcagtatcgt tgtccggata aagcgttcac gccgcatctg gctaacaatg
    55441 acacgcactg cagcgtgctt taatgggttt ctcacgatcg taccgctctg ctcctcgcta
    55501 agttgttctg tgagttatag ttatagagaa atcacgggta cgaatgttga acagatggcg
    55561 acgtcacctg ttcaacgacc aaccacacgg ccctcattac gacccctgaa cacaaacggt
    55621 aatggcaaat gtcattaaat attagtaaga tagcctcttt acataaaatc ccttaatatt
    55681 atgcgccagg tattatcgtc tcttttggtg attgctggac ttgtgagtgg tcaggcaatc
    55741 gccgcgcctg aatctccccc gcatgctgat atccgcgaca gcggttttgt ctattgcgtc
    55801 agcgggcaag tcaacacctt taacccatcc aaagcgagca gtgggttaat tgtcgatacc
    55861 cttgccgccc agttttatga tcgactgctg gatgtcgatc cctataccta tcgcctgatg
    55921 ccggaacttg ccgaaagctg ggaagtactc gacaacggcg cgacctatcg cttccacctg
    55981 cgtcgcgatg ttccgtttca aaaaaccgac tggtttactc ccactcgtaa aatgaatgcc
    56041 gacgatgtgg tgtttacctt ccagcgaatt tttgaccgca acaacccgtg gcataacgtc
    56101 aacggcagca acttccccta cttcgacagc ctgcaatttg ccgataacgt gaaaagcgtc
    56161 cgcaaactgg ataatcatac cgttgagttc cgactcgccc agccggatgc ttcttttttg
    56221 tggcacctcg caacccatta tgcttcggtc atgtcggcag aatatgcccg gaagttagag
    56281 aaagaagatc gccaggagca actcgaccgt caaccggtcg gcaccggtcc gtatcagttg
    56341 tcggaatacc gcgccgggca atttattcgc ctacaacgtc atgatgactt ctggcgcggt
    56401 aaaccgttaa tgccgcaggt agtggtggat ttaggctccg gcggcaccgg acgtctgtcg
    56461 aaactcctga ccggggaatg cgacgttctg gcctggcctg ctgccagcca gctatccatt
    56521 ttgcgtgacg acccgcgctt gcgtttaacg ctgcgtcctg ggatgaacgt cgcctatctg
    56581 gcatttaaca ccgccaaacc gccgctaaat aatcccgctg tccgccatgc gctggcactg
    56641 gcgattaata accagcgcct gatgcaatcc atctattatg gtacggctga aacggcggcc
    56701 tctattttac cgcgcgcctc gtgggcctat gacaacgagg ctaaaattac tgaatacaat
    56761 ccggcgaaat cgcgcgaaca gttgaagtcg ttggggctgg aaaatttaac gctgaaactg
    56821 tgggtgccca cacgttcgca ggcgtggaac cccagtccac tgaaaactgc cgaactgatt
    56881 caggcggata tggcgcaggt tggcgtaaaa gtggtgattg tgccggtaga aggtcgcttt
    56941 caggaggcgc ggttgatgga tatgagccat gatctgacgt tatccggttg ggcgacggac
    57001 agtaacgacc cggacagttt cttccgtccg ttactgagct gcgcggcaat tcattcgcag
    57061 accaacctcg cccactggtg cgatccgaaa ttcgacagcg tattgcgtaa ggcgctctct
    57121 tcgcagcagc tggcggcgcg tattgaagcc tatgacgaag cgcagagtat tctggcgcag
    57181 gaattgccca ttttgccgct ggcgtcgtca ttgcgtttgc aggcctatcg gtacgatatc
    57241 aaaggtctgg tacttagccc gtttggtaac gcctcctttg ctggggtgta tcgcgagaaa
    57301 caggatgagg tgaaaaaacc atgattatct tcaccttacg ccgcattttg ttattgattg
    57361 tcaccttgtt cctgctgacc ttcgttggct tcagcttgag ctatttcacc cctcatgcgc
    57421 cgttacaagg cgcgtcactg tggaatgcct gggtgttctg gtttaacggc ctgatccact
    57481 gggattttgg tgtttccagc attaacggtc aaccgattgc cgaacagtta aaagaggtct
    57541 tcccggcgac gatggaactg tgcatcctcg ccttcggttt tgcgctgatt gttggcatcc
    57601 ccgtggggat gattgccggg attacgcgcc ataagtggca ggataacttg atcaacgcca
    57661 tcgccttact gggcttttca atcccggtgt tctggctggc gcttctgttg acgctgtttt
    57721 gttcactcac gctaggttgg ttgcccgttt cagggcgttt cgatctgctc tacgaagtga
    57781 aaccgattac cggttttgcg ttgattgatg cctggctttc ggactcacca tggcgggatg
    57841 aaatgatcat gagcgcaatc cgccatatga tattgcccgt gatcaccctg tcggttgcgc
    57901 caacaactga agtgatccgc ctgatgcgta tcagcactat cgaagtgtat gaccagaact
    57961 atgtaaaagc ggcggcgacc cgcggtttgt cgcgctttac tattttgcgt cgccacgttc
    58021 tgcataacgc gttaccgccg gttattcctc gcctgggctt acagttttcc accatgctga
    58081 cgctggcgat gatcaccgaa atggttttta gctggccggg tttagggcgc tggttaatta
    58141 acgccatccg ccagcaggat tacgcagcca tttccgccgg agtgatggtg tgtggctcac
    58201 tggtcattat tgttaacgtg atttctgata ttttgggtgc catggctaac cctctgaaac
    58261 ataaggaatg gtatgcctta cgatagcgta tacagcgaaa agcgcccgcc gggcacgctg
    58321 cgtaccgcct ggcgcaaatt ttatagtgac gcctctgcga tggtcggcct gtacggctgc
    58381 gcggggctgg ctgtactgtg tatttttggc ggctggtttg cgccttacgg catcgaccag
    58441 caatttctcg gttatcaatt attgccgccg tcatggtcgc gctatggcga agtttctttc
    58501 ttcctgggga ctgacgacct cggacgcgat gttttaagcc gtttactgag cggagctgcg
    58561 ccaaccgtgg gtggcgcatt tgtggtgacg cttgccgcga cgatctgtgg cctggtactg
    58621 ggcaccttcg ccggggcgac acacggcctc cgctcagcgg tgcttaacca tattctggat
    58681 accttactgg cgatcccttc gctgctgttg gcaattatcg ttgtagcgtt tgccggaccg
    58741 agtttgtccc acgctatgtt tgctgtctgg ctggcattgc tgccgcgtat ggtacgttcg
    58801 atttacagca tggtgcatga cgaactggaa aaagagtacg ttatcgccgc ccgtctggat
    58861 ggcgcatcaa cgctgaatat tctctggttt gctgtgatgc caaacatcac cgccgggctg
    58921 gtcaccgaga tcacccgcgc actgtcgatg gcaattctcg atatcgccgc gctgggcttt
    58981 ctcgatctcg gcgcacaact cccctcgcct gaatggggag cgatgctcgg tgatgcgctg
    59041 gaactgattt atgtcgcccc gtggactgtc atgctgccag gtgcggcaat tatgattagc
    59101 gtgttgttgg ttaacctcct tggcgatggc gttcgtcgtg cgattattgc gggggtggaa
    59161 taatgccatt actcgatatt cgtaacctga ccattgaatt taaaaccggt gatgagtggg
    59221 ttaaagccgt cgaccgggta agtatgacct taaccgaagg tgaaatccgc ggtcttgttg
    59281 gtgaatccgg ttccggcaag agtttgattg cgaaagcgat ttgtggggtg aataaagata
    59341 actggcgtgt tactgctgac cgtatgcgtt ttgatgatat cgatttgctg cgtctctccg
    59401 cacgcgaacg gcgcaaactg gttggccata acgtgtcgat gattttccag gaaccgcagt
    59461 cgtgtcttga cccttcagaa cgtgtgggcc gccagttgat gcaaaacatc ccagcctgga
    59521 cctataaagg ccgttggtgg cagcgttttg gctggcgcaa acgccgtgcc attgaactgc
    59581 tgcaccgcgt ggggattaaa gatcacaaag atgcgatgcg cagttttccc tatgagttga
    59641 ccgaaggtga atgtcagaaa gtgatgatag ccattgcact ggcgaatcaa ccgcgtctgc
    59701 tgattgctga cgaaccgacc aactcaatgg agccaacaac ccaggcgcaa atctttcgcc
    59761 tgctgacgcg tctcaaccaa aacagcaata ccactatttt gcttatcagc catgacttac
    59821 aaatgcttag ccaatgggcg gataaaatta acgtgcttta ctgcggtcaa acagtggaaa
    59881 ccgcgccgag taaggagttg gtgacgatgc cacatcatcc ttatacccag gcgctgatcc
    59941 gcgcgatacc agacttcggc agcgcgatgc cgcataaaag tcgcctcaat acgctgcccg
    60001 gcgctatccc actgctggaa cagttaccga ttggttgtcg tctggggcca cgttgcccgt
    60061 atgcacaacg agaatgcatt gtgacgccac gtttgacggg ggcgaaaaat catctctatg
    60121 cctgtcattt cccgctgaac atggagaaag agtgagatga tcgaaacgct gcttgaagtg
    60181 cgtaatttaa gtaaaacgtt ccgctaccgg accggctggt ttcgtcgtca gaccgtagaa
    60241 gcggtaaaac ccttgagctt tacgctacgt gaaggccaga cactggcgat tattggcgag
    60301 aatggttcgg gtaaatccac gctggcaaaa atgctggcgg gaatgataga gcctaccagc
    60361 ggcgagttat tgattgacga tcatccactg cattttggcg attattcctt ccgcagtcag
    60421 cgtattcgca tgatttttca ggatccttcg acctcgttga atccccgtca acgtatctcg
    60481 caaattctgg attttccact gcgcctgaac accgacctgg aaccggaaca gcgtcgcaaa
    60541 cagattattg aaacgatgcg tatggttggg ctgctaccgg atcacgtcag ttactatccg
    60601 catatgttgg cacccggaca aaaacagcgt ctgggtctgg cgcgcgcgct gatattgcgc
    60661 ccaaaagtca ttattgccga tgaagccctc gcttcactgg atatgtcgat gcgttcgcag
    60721 ttgattaatc tgatgctgga attacaggaa aaacagggca tttcgtatat ttatgttacc
    60781 cagcatatcg gaatgatgaa gcacattagc gaccaggtgc tggtgatgca tcagggcgag
    60841 gttgtcgagc gaggcagcac cgcggatgtg ctggcatcgc cgctgcatga actcaccaaa
    60901 cggctgattg ccggtcattt tggcgaggca ttgacggcgg atgcgtggcg taaagatcgc
    60961 taattttctg aatcctcctt ccagattatt cacctcattc tgacaaaaga ttaaatcttg
    61021 tcagaatgag gtgatagata aaattaaatc aaatgcgcgt gatttaagac gcaatctcac
    61081 tttgcaggaa cgaaagctct ggcgatatct tcgcagccga cgttttagtg atttcaaatt
    61141 tcgccgtcaa catccagtgg ggagctacat tctcgatttt gcttgctgct cggcgcgtgt
    61201 agtcgttgag ctggatggtg ggcagcatga tttagcagtt gcctatgatt ccaggcgcac
    61261 tagctggctt gagtcgcagg gctggaccgt gctgcgtttc tggaataacg agattgattg
    61321 taatgaggag acggtgctgg agaatattct gcaggaactg aaccgccggt caccctctcc
    61381 ctgaaagagc gagggggcag accgagccga atagctgttg tggtgaaaac atggagacgg
    61441 tgctggagaa tattcggcaa ggtctgaacc gtcccagcca tcgccatgaa agggttaggg
    61501 gctgtatgag cctgtttgtt gctggggtaa caatatttgc acaatacggt cccctcgccc
    61561 ctctggggag agggttaggg tgaggggaaa agcgcccccc ctgccgcagc ctgctccggt
    61621 cggacctggc aactatagct actcacagcc aggttgatta taataaccgt ttatctgttc
    61681 gtactgttta ctaaaacgac gaatcgcctg attttcaggc acaacaagca tcaacaataa
    61741 ggattaaagc tatgggtttt ctttccggta agcgcattct ggtaaccggt gttgccagca
    61801 aactatccat cgcctacggt atcgctcagg cgatgcaccg cgaaggagct gaactggcat
    61861 tcacctacca gaacgacaaa ctgaaaggcc gcgtagaaga atttgccgct caattgggtt
    61921 ctgacatcgt tctgcagtgc gatgttgcag aagatgccag catcgacacc atgttcgctg
    61981 aactggggaa agtttggccg aaatttgacg gtttcgtaca ctctattggt tttgcacctg
    62041 gcgatcagct ggatggtgac tatgttaacg ccgttacccg tgaaggcttc aaaattgccc
    62101 acgacatcag ctcctacagc ttcgttgcaa tggcaaaagc ttgccgctcc atgctgaatc
    62161 cgggttctgc cctgctgacc ctttcctacc ttggcgctga gcgcgctatc ccgaactaca
    62221 acgttatggg tctggcaaaa gcgtctctgg aagcgaacgt gcgctatatg gcgaacgcga
    62281 tgggtccgga aggtgtgcgt gttaacgcca tctctgctgg tccgatccgt actctggcgg
    62341 cctccggtat caaagacttc cgcaaaatgc tggctcattg cgaagccgtt accccgattc
    62401 gccgtaccgt tactattgaa gatgtgggta actctgcggc attcctgtgc tccgatctct
    62461 ctgccggtat ctccggtgaa gtggtccacg ttgacggcgg tttcagcatt gctgcaatga
    62521 acgaactcga actgaaataa tcgttctgtt ggtaaagatg ggcggcgttc tgccgcccgt
    62581 tatctctgtt atacctttct gatatttgtt atcgccgatc cgtctttctc cccttcccgc
    62641 cttgcgtcag gataacgatt tcctttacga ccaaggagcg cccatggaac aacgccacat
    62701 caccggcaaa agccactggt atcatgaaac gcaatccagt actacggagt atgacgttct
    62761 gcctctggtc ccggaagccg caaaggtcag cgatcccttt ctactcgacg tgatccttga
    62821 aaaagaaacg ctggccccct tcctttcatg gctggaccct gcgcgtgttc ttgcagtgga
    62881 tttgttccct gaccagctta ccgtgacccg ttcacagacc ttcaccgctt atgaacgctt
    62941 gtcgacggcc ctgacggttg ctcaggtttg cggcgtccag cggttatgta actactattc
    63001 ggcgcgactt acgccgctcc ccgggcctga ttccaccagg gaaagtaatc atcggttggc
    63061 acaaatcacg caatatgccc gccaactggc tagctcgcct tctattatcg acaaccgatc
    63121 gcgccagcat ctgaatgacg tcggtcttac tgcctgggac tgtgtgatca ttagccaaat
    63181 cattggtttt attggctttc aggcgcggac aattgcgaca tttcaggctt atctcgggca
    63241 tccggtacgc tggttacccg ggctggagat acaaaactac gccgacgcgt cactgtttgc
    63301 tgatgaatca ttacgctggc gaagcagcta tgaggtggaa aaactacctg aagagcacac
    63361 aaaaagttca actgcagaac tttgccaact ggccgaaata ctctctctcc accctatttc
    63421 actttccctt ctcgaaaagt tgttaaacag cacacggggc aatacacagc cggataatca
    63481 gcttgcggcg ttgttatgcg cgcgtataaa tggcagtcct gcttgttttg ccacctgtat
    63541 ggattcatca aatgaatata aaaaaatcag cacccttatg cgcaagggcg aaaatgaaat
    63601 taaccaatgg gctgaccgtc attctgttga gcgcgctacc gttcaggcga tacaatggct
    63661 gacccgagca cccgatcgct ttagcgccgc ccagttcagc cctttactcg aacacgaaaa
    63721 atcatcaacg cagattatta atctgctggt atggagcggg ctgtgtggct ggataaatcg
    63781 cttaaaaatc gcgttgggtg agacatatta accttgccgc gtcagacaga ttcgcgtaaa
    63841 actgtcagcc gctctaatgg ccaccaaaat agacaattat gtttcaggac aacccgctgc
    63901 tagcgcagct taaacagcaa ctgcattccc agacgccacg cgctgaaggg gtggtaaaag
    63961 ccacagaaaa aggctttggc ttcctggaag tcgacgcgca aaaaagttat ttcattccgc
    64021 cgccgcagat gaaaaaagtc atgcatggcg accgaattat cgcggtgatc cacagtgaaa
    64081 aagaacgtga atccgcagag ccagaagaac tggttgaacc gttcctgact cgtttcgtgg
    64141 gtaaggttca gggcaaaaat gaccgtctgg ccatcgttcc tgatcatcca ctcttaaaag
    64201 acgccattcc ttgccgcgca gcccgtggcc tgaaccacga gtttaaagaa ggcgactggg
    64261 cggttgccga aatgcgccgt catccgctga aaggcgatcg ttctttctat gcagaactga
    64321 cacaatacat cacttttggt gacgatcact ttgtaccgtg gtgggttacc cttgcacgcc
    64381 ataatctgga aaaagaagca ccagacggcg tcgctaccga aatgctcgat gaaggtctgg
    64441 ttcgtgaaga tctgaccgcg ctggattttg tcaccatcga cagtgccagc acagaagata
    64501 tggatgacgc ccttttcgct aaggcgttgc cggatgacaa acttcagctg attgtggcga
    64561 ttgccgatcc aaccgcgtgg attgctgaag gcagcaagct ggacaaagcc gcgaaaattc
    64621 gcgcattcac caactatctg cctggcttca acatccctat gctgcctcgc gagctttctg
    64681 acgatctctg ctcactgcgc gccaatgaag tccgcccggt actggcatgc cgcatgacgc
    64741 tctccgctga tggcaccatt gaagataata tcgaattctt tgccgccacc atcgaatcca
    64801 aagcaaagct ggtgtatgac caggtttctg actggctgga aaataccggt gactggcagc
    64861 ctgaaagtga agcaattgcc gaacaagtcc gtttgctagc gcaaatttgc caacgccgcg
    64921 gcgagtggcg tcataaccac gcactggtgt ttaaagatcg cccggattac cgctttattc
    64981 tcggtgaaaa aggtgaagtg ctggatatcg tcgccgagcc tcgtcgcatt gccaaccgta
    65041 tcgtcgaaga agcgatgatt gccgctaaca tttgtgcggc ccgcgtactg cgcgataagc
    65101 tcggttttgg catctataac gtgcatatgg gctttgatcc ggcgaatgcc gacgcgctgg
    65161 cagcgttgct gaaaacgcac ggtctgcatg tcgatgccga agaagtgctc acgctggacg
    65221 gtttctgcaa actgcgtcgt gaactggacg cgcaaccaac tggtttcctc gacagccgca
    65281 ttcgtcgctt ccagtcattt gctgaaatta gcactgaacc cggtcctcac tttggcctcg
    65341 gtctggaagc atacgccacc tggacttcgc cgatccgtaa atatggcgac atgatcaacc
    65401 accgtctgct gaaagcggtt atcaaaggcg aaactgcgac gcgcccacag gatgaaatca
    65461 ctgtccaaat ggccgagcgt cgccgtctca accggatggc agaacgtgat gttggtgact
    65521 ggttatacgc acgcttcctg aaagacaaag ccgggaccga cacccgtttc gcagcggaaa
    65581 ttgtcgatat cagccgtggc ggcatgcgtg ttcgtttggt tgataacggc gctatcgcct
    65641 ttattccggc acctttctta cacgctgtgc gcgatgaact ggtttgcagc caggaaaacg
    65701 gcactgtaca aattaaaggt gaaacggttt acaaagtgac tgacgttatt gacgtcacta
    65761 ttgccgaagt ccgcatggaa acccgcagca ttattgcgcg cccggtcgcg taatctcctt
    65821 tcacggccca ttcctcatgg atgggccgtt tatttccccg ctctaccttc gttatatcca
    65881 ggcagatttt ttaactgact ttcgtttgaa aactggcgtt tttccaaaac tggattacaa
    65941 ataaatatat aaaaaaaaca atgcgtttag ccgccgttaa tttcatgtaa gtcatgttgt
    66001 tccttttatt taaccgcgga ctccgctgtt aaccggagga tatgcatcat gaaaaccgtt
    66061 agggagtcca caacgttgta caactttctc ggatcgcaca atccatactg gcggttgacg
    66121 gaaagcagcg atgttttgcg cttttctacc accgaaacca cagaacctga tcgtacattg
    66181 cagttatctg ccgaacaggc tgctcgcatc agggaaatga cggtcatcac ctccagcctg
    66241 atgatgagtc tgaccgtcga tgaaagcgat ctttctgtgc atctggtagg acgaaaaatc
    66301 aataaacggg aatgggctgg caacgcgtct gcatggcatg acacaccggc ggttgctcgt
    66361 gatttatcac acgggctttc ctttgctgag caggtagttt ctgaagcaca ttccgcaata
    66421 gtgattctcg acagccgggg gaatatccaa cgcttcaatc ggttatgtga agattacaca
    66481 gggttgaaag aacacgacgt cattgggcaa agcgtgttta aactgtttat gagccgtcgt
    66541 gaagctgcgg catccaggcg caataaccgt gtattttttc gaagcggcaa tgcatatgaa
    66601 gtcgaactgt ggataccaac atgtaaaggc cagcggctgt ttctgtttcg caataaattt
    66661 gtccacagcg gcagtggcaa aaacgagatt tttttaatct gttccggcac cgacattacc
    66721 gaagagcgcc gcgctcagga gcgactgcgt attctggcaa ataccgacag tatcaccgga
    66781 ctgccgaatc gtaacgcaat gcaggattta atcgatcacg ctattaatca tgcagataac
    66841 aataaagttg gggttgtgta tcttgatttg gataatttca aaaaggtcaa cgacgcctat
    66901 gggcatttgt ttggtgacca gttattacgc gacgtgtcat tggctatttt aagctgtctc
    66961 gaacatgacc aggtgttggc gcgtccaggt ggggatgagt ttctggtact ggcatccaac
    67021 acctcacaaa gcgcgctgga agcaatggca tcacgaattt tgacccgctt acggctcccc
    67081 tttcgcattg gtttaattga agtttatacc agctgttcag taggtattgc actctctccc
    67141 gaacatggtt cagacagcac ggctattatt cgtcacgccg acacagcaat gtacacagcg
    67201 aaggaaggcg gacgaggaca attttgcgtt tttaccccag aaatgaatca acgggtattt
    67261 gaatatctct ggctggatac caacttgcgt aaagcactgg aaaacgatca gttggttatt
    67321 cactatcaac cgaaaatcac ctggcgtggc gaagtgcgca gtctggaagc actagtacgt
    67381 tggcagtcac ctgaacgtgg gttgattcca ccgttggact tcatttccta cgccgaagag
    67441 tcagggctaa ttgtgccttt aggccgttgg gtgattctcg atgtcgtacg ccaggtggca
    67501 aagtggcggg ataaaggcat aaacctgcga gtggcggtaa atatttctgc acgtcagctc
    67561 gccgatcaaa ccattttcac cgccctgaaa caggttctcc aggaactcaa ttttgaatac
    67621 tgccctatag atgttgaact gacagagagt tgtctgattg agaatgatga actggcactg
    67681 tctgttattc aacaatttag ccaactaggt gcgcaagtgc atctggatga ttttggtacc
    67741 ggctactctt cactttcgca actggcgcgc tttccgatcg atgccatcaa acttgaccag
    67801 gtttttgttc gagatattca caaacaacct gtctcgcagt cactggtccg ggcgatcgtc
    67861 gctgtggccc aggcattgaa tcttcaggtg atcgccgaag gtgtagagag tgcaaaggaa
    67921 gatgcttttt taaccaagaa cgggatcaat gagcggcaag gatttttgtt tgccaaaccg
    67981 atgcccgccg tcgccttcga acgctggtat aaacgctatc tgaagcgcgc ataagtagat
    68041 gaatatatat acttagcgct atatcccgtc attatatatc gtattcctgg atgataatta
    68101 gccgttgctg ttaaacactt ctcttttagc ggcaattttt gcattattca ttttccccct
    68161 tttgctataa ggatgtcctt gatgtctgaa tttgatgccc agcgcgttgc cgaacgtatt
    68221 gatattgtgt tagatatcct tgtggcaggc gattaccact ctgcgatcca taatctcgag
    68281 atacttaaag cagaactctt gcgccaggtt gctgaatcta cgccagacat cccgaaggca
    68341 ccgtgggaga tttaacaatc gtgccttcag gttttcctat ttgaggatgc ccggcgcgtc
    68401 agtatttttt tattaagtat tataacgtta taagaattac agcgatgaat tcccgacaac
    68461 aaactattct acagatggtc attgaccagg gtcaggttag cgtaaccgat ctggcaaaag
    68521 ccactggagt ttctgaagtt accattcgcc aggatctcaa cacactcgaa aaactgagtt
    68581 acctccgccg tgcacatggc tttgctgttt cgcttgatag tgatgacgtc gaaacccgta
    68641 tgatgagcaa ctatacgctg aagcgtgaac tcgccgagtt tgccgcgtcg ctggttcaac
    68701 cgggcgaaac catctttatc gaaaatggca gcagcaatgc cctactcgcc cggactctgg
    68761 gcgagcagaa gaaaaatgtc actatcatca cggtcagcag ctacatcgcg catttgctga
    68821 aagacgcgcc ttgtgaagtt attttgctcg gtggcgtgta tcagaaaaaa agcgaaagta
    68881 tggttggccc tttgacacgc cagtgcatcc aacaggtgca tttcagcaaa gcatttattg
    68941 gtattgatgg ctggcaacct gaaactggat ttaccggtcg cgatatgatg cgtaccgatg
    69001 tggtcaatgc cgtgctggaa aaagagtgcg aagcgatagt cctgactgac agctcgaaat
    69061 ttggtgctgt acattcatac tccatcggtc ccgttgagcg attcaatcgc gtgattaccg
    69121 attcgaaaat acgcgccagc gatctgatgc atcttgagca cagtaaactc accgttcacg
    69181 tcgttgacat ttaaccattt cccttctcta cggatgattt gcagtttggc aaatcatccg
    69241 ctctaagatg attcctggtt gataattaag actatttacc tgttattaac actctcaaga
    69301 tataaaatta ttatcagcga tataacagga agtcattatc acctgcgtga tataaccctg
    69361 cgcgcgagca gatttcacgg aataatttca ccaggcttat tcttagctat tatagttata
    69421 gagagcttac ttccgtgaat cataaattca ggagagagta ttatgtttgt aacgagcaaa
    69481 aaaatgaccg cggctgttct ggcaattact ttggcaatgt ctctgagtgc ctgttctaac
    69541 tggtctaaac gggaccgcaa caccgcaatc ggcgcgggtg caggggcatt aggcggtgca
    69601 gtactgaccg atggcagtac gttgggtaca ttaggtggtg cagctgtcgg tggtgttatt
    69661 ggtcaccagg tcggtaaata atcgtaaata aatgtcgatt atcgactcgc aattataata
    69721 cgcttgattc tgttcagtac gaaataactg aataatacgc acagtaaaat attcgaaagc
    69781 cacggatata tccgtggctt tttatgttaa ccgcctgcga gttttacctt catccctttc
    69841 gcttcaagta gtgattttaa taaatcacgc ttatcgccct ggatttcaat aactccatct
    69901 ttaactgctc cgccgcagcc gcattttttc ttcagttccg ctgcaagttt tgtcagttcg
    69961 gcatcatcga gatcgacacc ggtaatcagg caaacgccct tacctttacg tccactggtc
    70021 tgacgctgaa tacgcaccac accgtcgcct ttagggcgta caggggccgc tttgggctca
    70081 tcaatacgtc cggtttccgt tgagtagacc agacggctgt tggaatcact catcatgcac
    70141 tccgctgtaa agaggcgttg atcgctttca gcgtctgcgc tggatctacc gattgcgtta
    70201 ccgggcgacc aatcaccata taatcaacac cagccgacaa cgcctgttct ggcgtcataa
    70261 tgcggcgctg gtcaccagct tcactcccct gcggacgaat gcccggcgta accagtttga
    70321 actcctgacc gaatacctgt ttaaagcgca cagcttcctg agcagaacac accacaccat
    70381 caaggccaca tttttgcgtc agtgccgcca gacgttctgc ataatctgca ggtgacagtg
    70441 tcatgccaag atcgaccagg tcgctggctt ccatgctggt caacactgtc acagcaatca
    70501 aaagcggtgc atctttgcca aacggaacca gtgcctcacg cgctgcggtc atcatacgcg
    70561 ccccaccaga ggcatgaaca ttcaccatcc acacgcctaa gtcagctgca gcagcgacag
    70621 cgtgcgctgc agtgttgggg atatcgtgga atttcaggtc aagaaagata tcaaaaccac
    70681 gctgttgaag ttcgcgcaca aactgtggcc caaacaatgt aaacatctct ttgccgacct
    70741 tcagacgaca atcgcgtggg tcgatcttgt cgacaaaggc cagcgcgtca tcacgattat
    70801 gataatcaag ggcaacaacc acaggagaat tcgtaacagc gcgggaagaa gatgaagcag
    70861 ttaacgtcat gaccagacct tcttgatgat gggcaccgga agtggcgcga aacaggtaaa
    70921 cggcgagcat tctacccgtg gaaataaaaa attaacagtt gcgatttctc ccctggcagg
    70981 ctttttctgc gccgtcgttg ccggagcaca atggaacatt aataattagt atgttgtaac
    71041 taaagtcgga ttttttttaa aaattacagg ccatcaagac cgcgaatcgg tttaatggtt
    71101 gaccaggccc gacaagacgg acaatgccag tagagggtgt atgcggtaaa accacatttc
    71161 tggcaacgat aacgaggctt actacgtacc ttctcgccaa ccatgtcacg cagcaccatc
    71221 aggctctctt tggcacgccc ttcttccgct tcatttaagt ggtaatccat taacttatgg
    71281 aacacacgca tggtcggatg acgctgaagc tggcgcgtaa tatagacctg tgcggcctca
    71341 ctaccgtcgc gcgcttcgat gatatcagca agcatcaatt cagcatcggc accggtgttc
    71401 tcttccaccg cacgctgcag gaattctgcc cattcggcag ttttacccaa ctgctgatag
    71461 caggtttgca acatttccag cgtttcgctg accagttctc tgtcctggga tatcacgcgt
    71521 tgcagacttt cgacggcttt ggcgtattct cctttcgcca taaacacgcg tcccatcatt
    71581 atggatacgc gggcgctgtt tttatctgcc gccgcccctt tttttagcaa ggtcatggca
    71641 cgatcgagat cgtcgctggc catatgctgc agggctaact cacagtagaa atgggcaatt
    71701 tcgacgcgct gtttatcttt acccagcttc accaggcgtt cggcaacatc aattgctttc
    71761 tgccactcac tggtagcctg gtagatttgt agcaactgtt gcagcgcgcc aatgcggaag
    71821 tcagtttcat cggtcagctg attgaacatg tcttccgcgc ggtcatataa cccggcggcc
    71881 atgtaatcac gccccagttg ttgaatcgcc aacagacgct gttcataggt cagcgaggcg
    71941 ctttccatta gggtctgatg gatgcgaata gcgcgatcaa cttcgccacg cgaacggaac
    72001 aggtttccga gcgtaaggtg ggcttcaacg gtgcctgtat cctctttaag catatcgaga
    72061 aacaggtcta ccgctttatc ctgttgatta ctaagcagga agttaacccc cgctacgtaa
    72121 tcacgcgaca agcggttggc ttcatcttgc ttgttttgtt gcgcacttct gcggcccata
    72181 taccagccat aggcagcggc tacaggcaaa agcagaaaca acaactccag catagaaagt
    72241 tattccttcg ccgctgacga gtgcggcact acagccacgt cagtcgcggg tgaaagctgg
    72301 ttttccagtc gctttatttt acgttcagcg cgcgccaggg aaacacgaac tcgcagccag
    72361 aacaggccac aaatcaacca accgatagca aaccccgcag caaacaatac cgccagcaat
    72421 gtggaaatac ggtactcccc ttgcgctaac agataattaa acgtcacctg ttgatcgttc
    72481 tgcgcaccca acgtgaccga aatcacgaag atcgctaaca ccagtaagaa aatgagtaaa
    72541 tatttcacat tacttcccgt tatgtggtta gagcgaataa attatggtca acttaccgca
    72601 atagcccttt aaagtaccat tttcgcgccg tctgcgaaat ggcatccaca cgcattgttg
    72661 atgatttaag ggctaaattc ggaaaatcaa ccagcgttaa ctttcttgtt ctcgttgcgc
    72721 tatttcgcga ttttcttccg caggtggtgt taatggccca caaattcgtt gcgcaagcca
    72781 cgttgccacc gccaccagcg cccacgaaat caacgtagct actaccagat cgcgtggcca
    72841 atgcatcccg agcagcaggc ggcttcccat gactcccgtt gcccagacca gcaagatagc
    72901 aatggttaac gttcgccgac gcggccacag caaaccaacg gccagcagtg cccaactggc
    72961 agcaaacatc gtgtgaccgg aaggaaaggc aaaccccgtc tctttctgcc agtgtgaacg
    73021 caaatattgt gggatatttt tctcttcagc caactgttct ttcactagat ttccgcgttc
    73081 tgctcgcttt aaagtgtaga actcatcaac cggaatatga tgtgtttttt ccagccagat
    73141 aacaaaaggt cgtggttcct ggactttgtc tttgatccag gatttaacgc cttgtcccac
    73201 aaggattgcg gccgccagaa tggcaaataa tacaaaggca gccttaatgc gaaaacgcag
    73261 acaccagaga aaccagccga ataaaatcaa atgtgtaatg acgccccagg gctgggtgac
    73321 agtttcagta acccaaaaag ccgcttttag tagccaactt tgttctccag gttgccaacg
    73381 ccagccagaa atccatacgg ctactggcat gacaagcaat agtgcagctc ccactgcggt
    73441 acgtctggca atcgaacgca tggcctctcc tttttgataa gtcccacaat cataactgaa
    73501 aacgccagtt ccaggaaaaa ttgacagatt tgtgccattc cgtgaacgat cgacgcgtcg
    73561 tgattaggtg aaccccttct cgttatggca aaataagcca atacagaacc agcattatct
    73621 ggagaatttc atgcagctta aacgtgtggc agaagccaaa ctgccaaccc catggggcga
    73681 tttcctgatg gtgggatttg aagaactggc aaccggacac gatcatgtcg cgctagtcta
    73741 tggcgatatt tccgggcata ccccggtact tgcgcgcgtc cattccgaat gtctgaccgg
    73801 tgacgccctg ttcagcttgc gctgcgattg tggcttccag ctcgaagcgg cattgacgca
    73861 aattgccgag gaaggccgtg gtattttgct gtatcaccgt caggaaggtc gtaacattgg
    73921 tctgctgaat aaaatccgcg cttacgcact gcaggatcaa ggttacgata ccgtagaggc
    73981 taaccaccag ttaggcttcg ccgctgatga gcgcgacttc actctttgcg ctgatatgtt
    74041 caaactcctt ggcgtcaatg aagtccgctt gttaaccaat aacccgaaaa aagtcgaaat
    74101 tctgaccgaa gcagggatta atattgttga acgcgtacca ttgattgtag gtcgtaaccc
    74161 caataacgaa cattatctcg ataccaaagc cgagaaaatg ggccatttgc tgaacaaata
    74221 accctcttgc attgtgtaat tcatttgctt gccggaagca aaataaccgg caagcaaata
    74281 gttgttactt caacatatta cgaatgacat aatgcaaaat gccgtcgttc tggtagtagg
    74341 tcaactccgt cgcggtgtcg atacgacaac ggcagggtac gacttcctgg ctaccatccg
    74401 cgcgcgtaag cgtcaccgga accgtcgcgc cgggttgtag gttttgcaga tcgccaatat
    74461 caatcttctc ttccccggtt agccctaacg ttttacgcgt tacgccttgc ggaaattcca
    74521 gcggcaggat gcccatgcca attaaattcg aacggtgaat tcgttcaaac gattcggcaa
    74581 tcaccacacg aataccaagc agacgcggac cttttgccgc ccagtcacga ctggagcctg
    74641 atccatactc tttcccggca atcaccgcca gcggcgtttg ctcctgctta tagcgcatcg
    74701 cagcatcata aatagagact acgtcgctgt caggtaaatg ccgcgtcatc cccccttcaa
    74761 cgccaggcac catttcatta cggatgcgaa tattggcgaa ggtgccgcgc atcatcactt
    74821 catggttacc acgccgcgaa ccgtaggagt taaagtcttt tcgctcaaca ccccgacctt
    74881 gtagatatcg acccgctggg ctgtcgggct taatactgcc cgccggagag atatggtcag
    74941 tggtgactga atcccccagc attgcgagga tccgcgcacc gtgaatatct tccactggtg
    75001 ctggtgttgc ctgcatttca tcaaagaaag gcgataagcg aatataggtt gagtcctcct
    75061 gccaaccgta ggtatcggat cgtgtgacgt taattccctt ccactctgct gtgccttcaa
    75121 aaacttctgc gtactctttg cggaacattt ctgtggagac ttgttctacc gcacgggcaa
    75181 tttcttgtgc cgatggccag atatctttca gataaaccgg atcgcctttg cgatcatggc
    75241 cgataggctc agaagccagg ttgatattca tatttcccgc cagcgcatag gcaaccacca
    75301 gcggcggcga ggccagccag ttagttttaa ccagcggatg gatacggcct tcaaagttac
    75361 ggttgccgga cagcaccgca ccgacggtta aatcgccttt tttgattgcc gtttcgatag
    75421 gatcgggcag cggcccagag ttaccaatac aggtggtaca accgtatccc acaaggttaa
    75481 accccagttc gtcgagatac ggtgtcagtt tcgcttttgc cagataatca gaaacgactt
    75541 tcgaacccgg tgccagcgac gctttgaccc atggttgccg cttgaggccc agagttacgg
    75601 cttttttcgc cagcaagcct gcggccatca gcacacttgg gttagaggtg ttggtgcacg
    75661 aggttatcgc agcaatgacc acagcgccat caggtaactg atactgatgt ccgttcataa
    75721 cataatcgac cggctggcga tctttatgcg tggcattcac ttccagttcg ttactggcgg
    75781 caaatgcttt tggtacatcg ggcagtgcaa cgcgatcctg tgggcgttta ggccctgcca
    75841 ggctcgcttc aacgtcattc atatccagtt ctaacgtact ggtaaaaatt ggttcatcgc
    75901 ccgggttacg ccacatgccc tgcgctttgg catatttttc gaccaactcg acctgatctt
    75961 cgctgcgccc gcttaaacgc atgtaatcga gggttacagc atcgattggg aagaagccac
    76021 aggtggcacc atattctggc gacatattgg caatggtggc gcgatccgcc aacggtagtg
    76081 aatccagacc atcaccataa aattcgacga atttccccac cacgccatgt ttgcgcagca
    76141 tttgggtaac agtgagaacc aggtctgtgg cggtaatacc ttcacgtaat tttccggtaa
    76201 gtttgaagcc cactacatcc gggataagca tggaaaccag ctggcctaac attgcggctt
    76261 ctgcttcgat cccaccaacg ccccacccca gcacgccaag gccgttgatc atggtggtgt
    76321 gcgagtcagt accaacgagt gtatccggat aagcaatcca ttcaccgtcc tgcaattcac
    76381 tccacactgc tttgccgaga tattcgaggt taacctgatg gcaaatgcct gtgcctggcg
    76441 gcacgacgct aaaccgactg aacgcttgct ttccccattt caggaacaca taacgttcgt
    76501 ggttgcgctc catttccagg cgtacgtttt cttcaaatgc ctcatcatca ccaaaacgat
    76561 cgacggtcac cgagtggtca atgaccaggt cgaccggtga gagcgggtta acctttgcag
    76621 tatcgccgcc gaggcgttta accgcttcgc gcattgccgc cagatcaaca acggcaggta
    76681 cgccggtaaa gtcctgcatc agcacccttg ccgggcggta ggcaatttca cggtcagcat
    76741 gggcattttt cagccatcct gccagcgcgt ggatatcctc ttcggtaacc gagttaccat
    76801 cctgccagcg cagcaggttt tcgagcaaaa ctttgagtga cttgggtaga cgggtgatat
    76861 cgcccagtga tttagcagca agcggcaggc tgtagtagtg gtaagtttta tctttggcct
    76921 gcaacgtgtc cttactggct tctcgtaggg ttgacgacat agctcctcct taatgacagg
    76981 gttgcgaagc cctgattctc ttcagggtga atattaaaga taacacaaac atcgcgtaac
    77041 gatttgataa caacccaaat tgataaaaga ggagaaacct tgtggcaaag caaatgacaa
    77101 ccccgccgca gcggggtcaa ggatcagtga gtaatgatcc agaggagttc ggcccagaag
    77161 agcatcgaca gagaaaacgc gcccatccag gaccaatatt tcatatttgt gttgatcata
    77221 ggctacaccc ttaacggtta ttattttgtg ttgagataac tcaagctgtt attgctgcgg
    77281 tgtattaaaa gccctttaat tcattaaaaa tgggtaataa gaatgatgat aattattgtt
    77341 tcggctgatc atcttcagca aacagttcta taaaggcttg ctgctgcgat gttagttgcc
    77401 agtcgtctgg aataacgacg gaacattccc gtttcgtttc tgtttcattg tcactatgct
    77461 ggcataatgg tgacgactcc agttgctcct gaccgaccat agttatcccc acactttcca
    77521 aatcagcagt gcgacaacca cccagaaaag tgcagaacca agaaaaaccg ccagccaggc
    77581 tttacgtttt aattcaggat cgcggcgggg ttcctgattt ccagaaggca ttgctaacct
    77641 catataatcg ccatcactta tcagcaagac gttgaacgat tggtgtaatt aatcatacga
    77701 tgagacaaat cctaaagaaa ctttagtcaa aa
//
LOCUS       DAPOAV010000009        71190 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.009, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000009 DAPOAV010000000
VERSION     DAPOAV010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 71190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71190
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.009"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..2492
                     /gene="htrE"
                     /locus_tag="RN951_000755"
     CDS             <1..2492
                     /gene="htrE"
                     /locus_tag="RN951_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Yad fimbria usher protein HtrE"
                     /protein_id="HDX2525804.1"
                     /translation="HTFLMGQNASNIDLSRYSEGNPAIPGVYDVSVYVNDQPIINQSI
                     TFVAIEGKKNAQACITLKNLLQFHINSPDINNEKAVLLARDETLGNCLNLTEIIPQAS
                     VRYDVNDQRLDIDVPQAWVMKNYQNYVDPSLWENGINAAMLSYNLNGYHSETPGRKNE
                     SIYAAFNGGMNLGAWRLRASGNYNWMTDSGSNYDFKNRYVQRDIASLRSQLILGESYT
                     TGETFDSVSIRGIRLYSDSRMLPPTLASFAPIIHGVANTNAKVTITQGGYKIYETTVP
                     PGAFVIDDLSPSGYGSDLIVTIEESDGSKRTFSQPFSSVVQMLRPGVGRWDISGGQVL
                     KDDIQDEPNLFQASYYYGLNNYLTGYTGIQITDNNYTAGLLGLGLNTSVGAFSFDVTH
                     SNVRIPDDKTYQGQSYRVSWNKLFEETSTSLNIAAYRYSTQNYLGLNDALTLIDEVKH
                     PEQDLEPKFMRNYSRMKNQVTVSINQPLKFEKKDYGSFYLSGSWSDYWASGQNRSNYS
                     IGYSNSTSWGSYSVSAQRSWNEDGDTDDSVYLSFTIPIEKLLGTEQRTSGFQSIDTQI
                     SSDFKGNNQLNVSSSGYSDNARVSYSVNTGYTMNKASKDLSYVGGYASYESPWGTLAG
                     SISANSDNSRQVSLSTDGGFVLHSGGLTFSNDSFSDSDTLAVVQAPGAQGARINYGNS
                     TIDRWGYGVTSALSPYHENRIALDINDLENDVELKSTSAVAVPRQGSVVFADFETVQG
                     QSAIMNITRSDGKNIPFAADIYDEQGNVIGNVGQGGQAFVRGIEQQGNISIKWLEQSK
                     PVSCLAHYQQSPEAEKIAQSIILNGIRCQIQ"
     gene            2509..3078
                     /locus_tag="RN951_000756"
     CDS             2509..3078
                     /locus_tag="RN951_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414680.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX2525805.1"
                     /translation="MIKTTPHKIVILMGILLSPSVFATDINVEFTATVKATTCNITLT
                     GNNVTNDGNNNYTLRIPKMGLDKIANKTTESQADFKLVASGCSSGISWIDTTLTGNAS
                     SSSPKLIIPQSGDSSSTTSNIGMGFKKRTTDDATFLKPNSAEKIRWSTDEMQPDKGLE
                     MTVALRETDAGQGVPGNFRALATFNFIYQ"
     gene            3090..3695
                     /gene="yadL"
                     /locus_tag="RN951_000757"
     CDS             3090..3695
                     /gene="yadL"
                     /locus_tag="RN951_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like protein YadL"
                     /protein_id="HDX2525806.1"
                     /translation="MMTFKNLRYGLSSSVVLAASLFSVLSYAATDSIGLTVITTVEMG
                     TCTATLVNDSDQDISVVDFGDVYISEINAKTKVKTFKLKFKDCAGIPNKKAQIKLTKR
                     ATCEGTANDGAGFANGSTAADKASAVAVEVWSTVTPATGSATQFSCVTPASQEVTIST
                     AANAVVYYPMSARLVVEKNKTVNNVTAGKFSAPATFTVTYN"
     gene            3722..4318
                     /locus_tag="RN951_000758"
     CDS             3722..4318
                     /locus_tag="RN951_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX2525807.1"
                     /translation="MHPTQRKLMKRIILFLSLLFCIACPAIAGQDIDLVANVKNSTCK
                     SGISNQGNIDLGVVGVGYFSGNVTPESYQPGGKEFTITVSDCALQGTGDVLNQLHIDF
                     RALSGVMAAGSRQIFANEISSGASNVGVVIFSTQDSANTFNVLNASGGSRSVYPVMSD
                     DMNGSSWKFSTRMQKIDPALSVTSGQLMSHVLVDIYYE"
     gene            4368..5607
                     /gene="yadC"
                     /locus_tag="RN951_000759"
                     /pseudo
     CDS             4368..5607
                     /gene="yadC"
                     /locus_tag="RN951_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414677.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial tip-adhesin YadC"
     gene            5721..6515
                     /gene="panB"
                     /locus_tag="RN951_000760"
     CDS             5721..6515
                     /gene="panB"
                     /locus_tag="RN951_000760"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HDX2525808.1"
                     /translation="MKPTTISLLQKYKQEKKRFATITAYDYSFAKLFADEGLNVMLVG
                     DSLGMTVQGHDSTLPVTVADIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAAT
                     VMRAGANMVKIEGGEWLVETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAG
                     DQLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDA
                     FGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH"
     gene            6527..7378
                     /gene="panC"
                     /locus_tag="RN951_000761"
     CDS             6527..7378
                     /gene="panC"
                     /locus_tag="RN951_000761"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HDX2525809.1"
                     /translation="MLIIETLPLLRQQILRLRMEGKRVALVPTMGNLHDGHMKLVDEA
                     KARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNG
                     TETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIR
                     KMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAG
                     ERDLDEIITIAGQELNEKGFRADDIQIRDADTLLEVSETSKRAVILVAAWLGDARLID
                     NKMVELA"
     gene            complement(7452..8354)
                     /gene="rpnC"
                     /locus_tag="RN951_000762"
     CDS             complement(7452..8354)
                     /gene="rpnC"
                     /locus_tag="RN951_000762"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-promoting nuclease RpnC"
                     /protein_id="HDX2525810.1"
                     /translation="MDAPSTTPHDAVFKQFLMHAETARDFLEIHLPVELRELCDLNTL
                     HLESGSFIEESLKGHSTDVLYSVQMQGNPGYLHVVIEHQSKPDKKMAFRMMRYSIAAM
                     HRHLEADHDKLPLVVPILFYQGEATPYPLSMCWFDMFYSPELARRVYNSPFPLVDITI
                     TPDDEIMQHRRIAILELLQKHIRQRDLMLLLEQLVTLIDEGYTSGSQLVAMQNYMLQR
                     GHTEQADLFYGVLRDRETGGESMMTLAQWFEEKGIEKGIQQGRQEVSQEFAQRLLSKG
                     MSREDVAEMANLPLAEIDKVINLI"
     gene            8628..9008
                     /gene="panD"
                     /locus_tag="RN951_000763"
     CDS             8628..9008
                     /gene="panD"
                     /locus_tag="RN951_000763"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HDX2525811.1"
                     /translation="MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAI
                     DIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWR
                     PNVAYFEGDNEMKRTAKAIPVQVA"
     gene            complement(9012..10241)
                     /locus_tag="RN951_000764"
     CDS             complement(9012..10241)
                     /locus_tag="RN951_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDX2525812.1"
                     /translation="MYKQAVILLLMLFTASVSAALPARYMQTIENAAVWAQIGDKMVT
                     VGNIRAGQIIAVEPTAASYYAFNFGFGKGFIDKGHLEPVQGRQKVEDGLGDLNKPLSN
                     QNLVTWKDTPVYNAPSAGSAPFGVLADNLRYPILHKLKDRLNQTWYQIRIGDRLAYIS
                     ALDAQPDNGLSVLTYHHILRDEENTRFRHTSTTTSVRAFNNQMAWLRDRGYATLSMVQ
                     LEGYVKNKINLPARAVVITFDDGLKSVSRYAYPVLKQYGMKATAFIVTSRIKRHPQKW
                     NPKSLQFMSVSELNEIRDVFDFQSHTHFLHRVDGYRRPILLSRSEHNILFDFARSRRA
                     LAQFNPHVWYLSYPFGGFNDNAVKAANDAGFHLAVTTMKGKVKPGDNPLLLKRLYILR
                     TDSLETMSRLVSNQPQG"
     gene            complement(10305..10745)
                     /locus_tag="RN951_000765"
     CDS             complement(10305..10745)
                     /locus_tag="RN951_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDX2525813.1"
                     /translation="MLGWVITCHDDRAQEILDALEKKHGALLQCRAVNFWRGLSSNML
                     SRMMCDALHEADSGEGVIFLTDIAGAPPYRVASLLSHKHSRCEVISGVTLPLIEQMMA
                     CRETMTSSEFRERIVELGAPEVSSLWHQQQKNPPFVLKHNLYEY"
     gene            complement(10850..11620)
                     /locus_tag="RN951_000766"
     CDS             complement(10850..11620)
                     /locus_tag="RN951_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001747261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX2525814.1"
                     /translation="MMHLYWVALKSIWAKEIHRFMRIWVQTLVPPVITMTLYFIIFGN
                     LIGSRIGDMHGFSYMQFIVPGLIMMSVITNAYANVASSFFGAKFQRNIEELLVAPVPT
                     HVIIAGYVGGGVARGLFVGILVTAISLFFVPFQVHSWVFVALTLVLTAVLFSLAGLLN
                     GVFAKTFDDISLVPTFVLTPLTYLGGVFYSLTLLPPFWQGLSHLNPIVYMISGFRYGF
                     LGINDVPLVTTFGVLVVFIVAFYLICWSLIQRGRGLRS"
     gene            complement(11617..12543)
                     /locus_tag="RN951_000767"
     CDS             complement(11617..12543)
                     /locus_tag="RN951_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX2525815.1"
                     /translation="MTIALELQQLKKTYPGGVQALRGIDLQVEAGDFYALLGPNGAGK
                     STTIGIISSLVNKTSGRVSVFGYDLEKDVVNAKRQLGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVERKEAYIRSEKYLKQLDLWGKRNERARMLSGGMKRRLMIARALMHEPKLLIL
                     DEPTAGVDIELRRSMWGFLKDLNDKGTTIILTTHYLEEAEMLCRNIGIIQHGELVENT
                     SMKALLAKLKSETFILDLAPKSPLPKLDGYQYRLVDTATLEVEVLREQGINSVFTQLS
                     EQGIQVLSMRNKANRLEELFVSLVNEKQGDRA"
     gene            12652..13314
                     /gene="can"
                     /locus_tag="RN951_000768"
     CDS             12652..13314
                     /gene="can"
                     /locus_tag="RN951_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonate dehydratase"
                     /protein_id="HDX2525816.1"
                     /translation="MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSD
                     SRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCG
                     GVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEMPQERRLDTLCELNVMEQVYNLGH
                     STIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLKHAN
                     HK"
     gene            complement(13355..13891)
                     /gene="hpt"
                     /locus_tag="RN951_000769"
     CDS             complement(13355..13891)
                     /gene="hpt"
                     /locus_tag="RN951_000769"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004204384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDX2525817.1"
                     /translation="MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRG
                     SFMFMADLCREVQVSHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDII
                     DSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDY
                     AQRYRHLPYIGKVILLDE"
     gene            14097..16487
                     /gene="gcd"
                     /locus_tag="RN951_000770"
     CDS             14097..16487
                     /gene="gcd"
                     /locus_tag="RN951_000770"
                     /EC_number="1.1.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinoprotein glucose dehydrogenase"
                     /protein_id="HDX2525818.1"
                     /translation="MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYP
                     IAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGI
                     WLILPFVWRRLVIPASGAVAALVVALLISGGILTWAGFNDPQEINGTLSADATPAEAI
                     SPVADQDWPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKQPNDPGEITNEV
                     TPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAE
                     TASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNLQSNMPDTKPGLYE
                     PTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSD
                     EHTFTFNSPNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATT
                     GKLAWSYQTVHHDLWDMDLPAQPTLADITVNGQKVPVIYAPAKTGNIFVLDRRNGELV
                     VPAPEKPVPQGAAKGDYVTPTQPFSELSFRPTKDLSGADMWGATMFDQLVCRVMFHQM
                     RYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGN
                     PMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEV
                     VWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSN
                     GEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK"
     gene            complement(16689..18239)
                     /gene="cueO"
                     /locus_tag="RN951_000771"
     CDS             complement(16689..18239)
                     /gene="cueO"
                     /locus_tag="RN951_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multicopper oxidase CueO"
                     /protein_id="HDX2525819.1"
                     /translation="MQRRDFLKYSVALGVASALPLWSRAVFAAERPTLPIPDLLTTDA
                     RNRIQLTIGAGQSTFGGKTATTWGYNGNLLGPAVKLQRGKAVTVDIYNQLTEETTLHW
                     HGLEVPGEVDGGPQGIIPPGGKRSVTLNVDQPAATCWFHPHQHGKTGRQVAMGLAGLV
                     VIEDDEILKLMLPKQWGIDDVPVIVQDKKFSADGQIDYQLDVMTAAVGWFGDTLLTNG
                     AIYPQHAAPRGWLRLRLLNGCNARSLNFATSDNRPLYVIASDGGLLPEPVKVSELPVL
                     MGERFEVLVEVNDNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQPIAISASGALPDTL
                     SSLPALPSLEGLTVRKLQLSMDPMLDMMGMQMLMEKYGDQAMAGMDHSQMMGHMGHGN
                     MNHMNHGGKFDFHHANKINGQAFDMNKPMFAAAKGQYERWVISGVGDMMLHPFHIHGT
                     QFRILSENGKPPAAHRAGWKDTVKVEGNVSEVLVKFNHDAPKEHAYMAHCHLLEHEDT
                     GMMLGFTV"
     gene            18405..18752
                     /locus_tag="RN951_000772"
     CDS             18405..18752
                     /locus_tag="RN951_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414664.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YacC family pilotin-like protein"
                     /protein_id="HDX2525820.1"
                     /translation="MKTFFRTVLFGSLMAVCANSYALSESEAEDMADLTAVFVFLKND
                     CGYQNLPNGQIRRALVFFAQQNQWDLSNYDTFDMKALGEDSYRDLSGIGIPVAKKCKA
                     LARDSLSLLAYVK"
     gene            18858..19724
                     /gene="speE"
                     /locus_tag="RN951_000773"
     CDS             18858..19724
                     /gene="speE"
                     /locus_tag="RN951_000773"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HDX2525821.1"
                     /translation="MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFG
                     RVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVE
                     SITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCT
                     DPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGF
                     YQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAIHTAAFALP
                     QYLQDALASQPS"
     gene            19740..20534
                     /gene="speD"
                     /locus_tag="RN951_000774"
     CDS             19740..20534
                     /gene="speD"
                     /locus_tag="RN951_000774"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HDX2525822.1"
                     /translation="MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYN
                     ANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLP
                     ETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
                     VTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSDDMKALYDMVDVNVYQENIFHTKML
                     LKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV"
     gene            complement(20572..20934)
                     /locus_tag="RN951_000775"
     CDS             complement(20572..20934)
                     /locus_tag="RN951_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414661.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YacL family protein"
                     /protein_id="HDX2525823.1"
                     /translation="MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQ
                     AAHALKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCG
                     VEDFLQVVAAYRNFVQQK"
     gene            complement(21110..23707)
                     /gene="acnB"
                     /locus_tag="RN951_000776"
     CDS             complement(21110..23707)
                     /gene="acnB"
                     /locus_tag="RN951_000776"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase"
                     /protein_id="HDX2525824.1"
                     /translation="MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEF
                     LLDLLTNRVPPGVDEAAYVKAGFLAAIAKGEAKSPLLTPEKAIELLGTMQGGYNIHPL
                     IDALDDAKLAPIAAKALSHTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRP
                     ALAEKLTVTVFKVTGETNTDDLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVG
                     PIKQIEALQQKGFPLAYVGDVVGTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGG
                     KIAPIFFNTMEDAGALPIEVDVSNLNMGDVIDVYPYKGEVRNHETGELLATFELKTDV
                     LIDEVRAGGRIPLIIGRGLTTKAREALGLPHSDVFRQAKDVAESDRGFSLAQKMVGRA
                     CGVKGIRPGAYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPK
                     PVDVNTHHTLPDFIMNRGGVSLRPGDGVIHSWLNRMLLPDTVGTGGDSHTRFPIGISF
                     PAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGITLRDLVHAIPLYAIKQGLLTVE
                     KKGKKNIFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTIKLNKEPIIEYLNSNI
                     VLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEADADAEYAAVIDIDLADIKEPIL
                     CAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAAGKLLDAHKGQLPTRLWVAPP
                     TRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVADGATVVSTSTRNFPNRLG
                     TGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDTYRYLNFNQLSQYTEKA
                     DGVIFQTAV"
     gene            24062..25915
                     /locus_tag="RN951_000777"
     CDS             24062..25915
                     /locus_tag="RN951_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3300 domain-containing protein"
                     /protein_id="HDX2525825.1"
                     /translation="MKMTLPFKPHVLALICSAGLCAASTGLYIKSRTVEAPVEPQSTQ
                     LAVSDAAAVTFPATVSAPPVTPAVVKSAFSTAQIDQWVAPVALYPDALLSQVLMASTY
                     PTNVAQAVQWSHDNPLKQGDAAIQAVSDQPWDASVKSLVAFPQLMALMGENPQWVQNL
                     GDAFLAQPQDVMDSVQRLRQLAQQTGSLKSSTEQKVITTTKKAVPVKQTVTAPVIPSN
                     TVLTANPVITEPATTVISIEPANPDVVYIPNYNPTVVYGNWANTAYPPVYLPPPAGEP
                     FVDSFVRGFGYSMGVATTYALFSSIDWDDDDHDHHHHDNDDYHHHDGGHRDGNGWQHN
                     GDNINIDVNNFNRITGEHLTDKNMAWRHNPNYRNGVPYHDQDMAKRFHQTDVNGGMSA
                     TQLPAPTRDSQRQAAANQFQQRTHAAPVITRDTQRQAAAQRFNEAEHYGSYDDFHDFS
                     RRQLLTQQQKDAARQRYQSASPEQRQAVRERMQTNPKIQQRREAARERIQSASPEQRQ
                     AVREKMQTNPQNQQRRDAARERIQSASPEQRQVFKEKVQQRPLNQQQRDNARQRVQSA
                     SPEQRQVFREKVQESRPQRLNDSNHTVRLNNEQRSAVCERLSERGARRLER"
     gene            complement(25986..27410)
                     /gene="lpdA"
                     /locus_tag="RN951_000778"
     CDS             complement(25986..27410)
                     /gene="lpdA"
                     /locus_tag="RN951_000778"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDX2525826.1"
                     /translation="MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGV
                     CLNVGCIPSKALLHVAKVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLA
                     GMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDP
                     RIWDSTDALELKEVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDI
                     VKVFTKRISKKFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPN
                     GKNLDAGKAGVEVDDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEV
                     IAGKKHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATFPWAASGRAIASDC
                     ADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHE
                     SVGLAAEVFEGSITDLPNPKAKKK"
     gene            complement(27735..29627)
                     /gene="aceF"
                     /locus_tag="RN951_000779"
     CDS             complement(27735..29627)
                     /gene="aceF"
                     /locus_tag="RN951_000779"
                     /EC_number="2.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex
                     dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HDX2525827.1"
                     /translation="MAIEIKVPDIGADEVEITEILVKVGDKVEAEQSLITVEGDKASM
                     EVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAPAQAEEKKEAAPAAAPAA
                     AAAKDVNVPDIGSDEVEVTEILVKVGDKVEAEQSLITVEGDKASMEVPAPFAGTVKEI
                     KVNVGDKVSTGSLIMVFEVAGEAGAAAPAAKQEAAPAAAPAPAAGVKEVNVPDIGGDE
                     VEVTEVMVKVGDKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIM
                     IFEVEGAAPAAAPAKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAENDAYVHATPLIR
                     RLAREFGVNLAKVKGTGRKGRILREDVQAYVKEAIKRAEAAPAATGGGIPGMLPWPKV
                     DFSKFGEIEEVELGRIQKISGANLSRNWVMIPHVTHFDKTDITELEAFRKQQNEEAAK
                     RKLDVKITPVVFIMKAVAAALEQMPRFNSSLSEDGQRLTLKKYINIGVAVDTPNGLVV
                     PVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTISSIGGLGTTHFAPIVN
                     APEVAILGVSKSAMEPVWNGKEFVPRLMLPISLSFDHRVIDGADGARFITIINNTLSD
                     IRRLVM"
     gene            complement(29642..32305)
                     /gene="aceE"
                     /locus_tag="RN951_000780"
     CDS             complement(29642..32305)
                     /gene="aceE"
                     /locus_tag="RN951_000780"
                     /EC_number="1.2.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008814576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring),
                     homodimeric type"
                     /protein_id="HDX2525828.1"
                     /translation="MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEA
                     RKGGVNVAAGTGISNYINTIPVEEQPEYPGNLELERRIRSAIRWNAIMTVLRASKKDL
                     ELGGHMASFQSSATIYDVCFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTQ
                     EQLDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLK
                     DTSKQTVYAFLGDGEMDEPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKII
                     NELEGIFEGAGWNVIKVMWGSRWDELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYV
                     REHFFGKYPETAALVADWTDEQIWALNRGGHDPKKIYAAFKKAQETKGKATVILAHTI
                     KGYGMGDAAEGKNIAHQVKKMNMDGVRHIRDRFNVPVSDADIEKLPYITFPEGSEEHT
                     YLHAQRQKLHGYLPSRQPNFTEKLELPSLQDFGALLEEQSKEISTTIAFVRALNVMLK
                     NKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVAYYKEDEKGQIL
                     QEGINELGAGCSWLAAATSYSTNNLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFL
                     IGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEK
                     QENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETIEGSKGKVQLLGSGSILRHVR
                     EAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPA
                     VASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGE
                     LAKRGEIDKKVVADAIAKFNIDADKVNPRLA"
     gene            complement(32466..33230)
                     /gene="pdhR"
                     /locus_tag="RN951_000781"
     CDS             complement(32466..33230)
                     /gene="pdhR"
                     /locus_tag="RN951_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex transcriptional
                     repressor PdhR"
                     /protein_id="HDX2525829.1"
                     /translation="MAYSKIRQPKLSDVIEQQLEFLILEGTLRPGEKLPPERELAKQF
                     DVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLWQSFSDPLVELLSDHPESQYDLLE
                     TRHALEGIAAYYAALRSTDEDKERIRELHHAIELAQQSGDLDAESNAVLQYQIAVTEA
                     AHNVVLLHLLRCMEPMLAQNVRQNFELLYSRREMLPLVSSHRTRIFEAIMAGKPEEAR
                     EASHRHLAFIEEILLDRSREESRRERSLRRLEQRKN"
     gene            33771..35144
                     /gene="aroP"
                     /locus_tag="RN951_000782"
     CDS             33771..35144
                     /gene="aroP"
                     /locus_tag="RN951_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transporter AroP"
                     /protein_id="HDX2525830.1"
                     /translation="MMEGQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSA
                     GPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSFAGFASGWNYWVL
                     YVLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIK
                     VIAVVAMIIFGGWLLFSGNGGPQATVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLE
                     LVGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIF
                     HELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALASVDKRGVPV
                     NTILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAKQEQG
                     VVTRFPALLYPLGNWICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGYLFKEKT
                     AKAVKAH"
     gene            complement(35187..36041)
                     /gene="ampE"
                     /locus_tag="RN951_000783"
     CDS             complement(35187..36041)
                     /gene="ampE"
                     /locus_tag="RN951_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase regulator AmpE"
                     /protein_id="HDX2525831.1"
                     /translation="MTLFTTLLVLIFERLFKLGEHWQLDHRLEAFFRRVKHFSLGRTL
                     GMTIIAMGVTFLLLRALQGVLFNVPTLLVWLLIGLLCIGAGKVRLHYHAYLTAASRND
                     SHARATMAGELTMIHGVPAGCDEREYLRELQNALLWINFRFYLAPLFWLIVGGTWGPV
                     TLMGYAFLRAWQYWLARYQTPHHRLQSGIDAVLHVLDWVPVRLAGVVYALIGHGEKAL
                     PAWFASLGDFHTSQYQVLTRLAQFSLAREPHVDKVETPKAAVSMAKKTSFVVVVVIAL
                     LTIYGALV"
     gene            complement(36038..36589)
                     /gene="ampD"
                     /locus_tag="RN951_000784"
     CDS             complement(36038..36589)
                     /gene="ampD"
                     /locus_tag="RN951_000784"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,6-anhydro-N-acetylmuramyl-L-alanine amidase
                     AmpD"
                     /protein_id="HDX2525832.1"
                     /translation="MLLEQGWLVGARRVPSPHYDCRPDDETPTLLVVHNISLPPGEFG
                     GPWIDALFTGTIDPQAHPFFAEIAHLRVSAHCLIRRDGEIVQYVPFDKRAWHAGVSQY
                     QGRERCNDFSIGIELEGTDTLAYTDAQYQQLAAVTRALIDCYPDIAKNMTGHCDIAPD
                     RKTDPGPAFDWARFRVLVSKETT"
     gene            36677..37570
                     /gene="nadC"
                     /locus_tag="RN951_000785"
     CDS             36677..37570
                     /gene="nadC"
                     /locus_tag="RN951_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HDX2525833.1"
                     /translation="MPPRRYNPDTRRDELLERINLDIPGAVAQALREDLGGTVDANND
                     ITAKLLPENSRSHATVITRENGVFCGKRWVEEVFIQLAGDDVTIIWHVDDGDVINANQ
                     SLFELEGPSRVLLTGERTALNFVQTLSGVASKVRHYVELLEGTNTQLLDTRKTLPGLR
                     SALKYAVLCGGGANHRLGLSDAFLIKENHIIASGSVRQAVEKASWLHPDAPVEVEVEN
                     LEELDEALKAGADIIMLDNFETEQMREAVKRTNGKALLEVSGNVTDKTLREFAETGVD
                     FISVGALTKHVQALDLSMRFR"
     gene            37773..38213
                     /gene="ppdD"
                     /locus_tag="RN951_000786"
     CDS             37773..38213
                     /gene="ppdD"
                     /locus_tag="RN951_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent pilin"
                     /protein_id="HDX2525834.1"
                     /translation="MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQ
                     TFVPYRTAVELCALEHGGLDTCDGGSNGIPSPTTTRYVSAMSVAKGVVSLTGQESLNG
                     LSVVMTPGWDNANGVTGWTRNCNIQSDSALQQACEDVFRFDDAN"
     gene            38223..39608
                     /gene="gspE"
                     /locus_tag="RN951_000787"
     CDS             38223..39608
                     /gene="gspE"
                     /locus_tag="RN951_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspE"
                     /protein_id="HDX2525835.1"
                     /translation="MNIPQLTALCLRYHGVLLDASEEVVHVAVVDAPSHELLDALHFA
                     TTKRIEITCWTRQQMEGHASRTQQTLPVAVQEKHQPKAELLTRTLQSALEQRASDIHI
                     EPADNAYRIRLRIDGVLHPLPDVSPDAGVALTARLKVLGNLDIAEHRLPQDGQFTVEL
                     AGNAVSFRIATLPCRGGEKVVLRLLQQVGQALDVNTLGMQPLQLADFAHALQQPQGLV
                     LVTGPTGSGKTVTLYSALQKLNTADINICSVEDPVEIPIAGLNQTQIHPRAGLTFQGV
                     LRALLRQDPDVIMIGEIRDGETAEIAIKAAQTGHLVLSTLHTNSTCETLVRLQQMGVA
                     RWMLSSALTLVIAQRLVRKLCPHCRRQQGEPIHIPDNVWPSPLPHWQAPGCVHCYHGF
                     YGRTALFEVLPITPVIRQLISANTDVESLETHARQAGMRTLFENGCLAVEQGLTTFEE
                     LIRVLGMPHGE"
     gene            39598..40800
                     /gene="hofC"
                     /locus_tag="RN951_000788"
     CDS             39598..40800
                     /gene="hofC"
                     /locus_tag="RN951_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein transport protein HofC"
                     /protein_id="HDX2525836.1"
                     /translation="MASKQLWRWHGITGDGNAQDGMLWAESRTLLLMALQQQMVTPLS
                     LKRIAINSAQWRGDKSAEVIHQLATLLKAGLTLSEGLALLAEQHPSKQWQALLQSLAH
                     DLEQGIAFSNALLPWSEVFPPLYQAMIRTGELTGKLDECCFELARQQKAQRQLTDKVK
                     SALRYPIIILAMAIMVVVAMLHFVLPEFAAIYKTFNTPLPALTQGIMTLADFSGEWSW
                     LLVLFGFLLAIANKLLMRRPTWLIVRQKLLLRIPIMGSLMRGQKLTQIFTILALTQSA
                     GITFLQGVESVRETMRCPYWVQLLTQIQHDISNGQPIWLALKNTGEFSPLCLQLVRTG
                     EASGSLDLMLDNLAHHHRENTMALADNLAALLEPALLIITGGIIGTLVVAMYLPIFHL
                     GDAMSGMG"
     gene            complement(40835..41878)
                     /gene="guaC"
                     /locus_tag="RN951_000789"
     CDS             complement(40835..41878)
                     /gene="guaC"
                     /locus_tag="RN951_000789"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008461816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HDX2525837.1"
                     /translation="MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQSW
                     SGVPIIAANMDTVGTFSMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVS
                     TGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVV
                     TGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVS
                     DGGCTTPGDVAKAFGGGADFVMLGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMK
                     RHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVGASRLKELTKRTTFI
                     RVQEQENRIFNNL"
     gene            complement(42034..42078)
                     /locus_tag="RN951_000790"
     CDS             complement(42034..42078)
                     /locus_tag="RN951_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2525838.1"
                     /translation="MIIKTLKMSARKRN"
     gene            42103..42723
                     /gene="coaE"
                     /locus_tag="RN951_000791"
     CDS             42103..42723
                     /gene="coaE"
                     /locus_tag="RN951_000791"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HDX2525839.1"
                     /translation="MRYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGA
                     PALHAIADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQ
                     ATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQA
                     TREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQFVSQEKP"
     gene            42723..43466
                     /gene="zapD"
                     /locus_tag="RN951_000792"
     CDS             42723..43466
                     /gene="zapD"
                     /locus_tag="RN951_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapD"
                     /protein_id="HDX2525840.1"
                     /translation="MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFF
                     RNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVL
                     ISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQAQRDSQVETWIAS
                     LNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGH
                     KSRFAIRFMPLDTENGQVPERLDFELACC"
     gene            43476..43673
                     /gene="yacG"
                     /locus_tag="RN951_000793"
     CDS             43476..43673
                     /gene="yacG"
                     /locus_tag="RN951_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor YacG"
                     /protein_id="HDX2525841.1"
                     /translation="MSETITVNCPTCGKTVVWGEISPFRPFCSKRCQLIDLGEWAAEE
                     KRIPSSGDLSESDDWSEEPKQ"
     gene            complement(43889..44278)
                     /gene="mutT"
                     /locus_tag="RN951_000794"
     CDS             complement(43889..44278)
                     /gene="mutT"
                     /locus_tag="RN951_000794"
                     /EC_number="3.6.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase MutT"
                     /protein_id="HDX2525842.1"
                     /translation="MKKLQIAVGIIRNENNEIFITRRAADAHMANKLEFPGGKIEMGE
                     TPEQAVVRELQEEVGITPQHFSLFEKLEYEFPDRHITLWFWLVERWEGEPWGKEGQPG
                     EWMSLVGLNADDFPPANEPVIAKLKRL"
     gene            complement(44338..47043)
                     /gene="secA"
                     /locus_tag="RN951_000795"
     CDS             complement(44338..47043)
                     /gene="secA"
                     /locus_tag="RN951_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDX2525843.1"
                     /translation="MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELK
                     GKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEM
                     RTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPG
                     MPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDE
                     ARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTE
                     RGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVI
                     IVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTG
                     TADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQ
                     PVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAG
                     RGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLEAGGLHIIGTERHESRR
                     IDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVT
                     KAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIRED
                     VFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERIL
                     AQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKD
                     PKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQ
                     LSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ"
     gene            complement(47105..47617)
                     /gene="secM"
                     /locus_tag="RN951_000796"
     CDS             complement(47105..47617)
                     /gene="secM"
                     /locus_tag="RN951_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414639.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secA regulator SecM"
                     /protein_id="HDX2525844.1"
                     /translation="MSGILTRWRQFGKRYFWPHLLLGMVAASLGLPALSNAAEPNAPA
                     KATTRNHEPSAKVNFGQLALLEANTRRPNSNYSVDYWHQHAIRTVIRHLSFAMAPQTL
                     PVAEESLPLQAQHLALLDTLSALLTQEGTPSEKGYRIDYAHFTPQAKFSTPVWISQAQ
                     GIRAGPQRLT"
     gene            complement(47848..48765)
                     /gene="lpxC"
                     /locus_tag="RN951_000797"
     CDS             complement(47848..48765)
                     /gene="lpxC"
                     /locus_tag="RN951_000797"
                     /EC_number="3.5.1.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-acyl-N-acetylglucosamine deacetylase"
                     /protein_id="HDX2525845.1"
                     /translation="MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDL
                     NPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIP
                     IMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTID
                     FNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVV
                     DDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVL
                     AKQEAWEYVTFQDDAELPLAFKAPSAVLA"
     gene            complement(48866..50017)
                     /gene="ftsZ"
                     /locus_tag="RN951_000798"
     CDS             complement(48866..50017)
                     /gene="ftsZ"
                     /locus_tag="RN951_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HDX2525846.1"
                     /translation="MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNT
                     DAQALRKTAVGQTIQIGSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAA
                     GMGGGTGTGAAPVVAEVAKDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSL
                     ITIPNDKLLKVLGRGISLLDAFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMS
                     EMGYAMMGSGVARGEDRAEEAAEMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFE
                     TVGNTIRAFASDNATVVIGTSLDPDMNDELRVTVVATGIGMDKRPEITLVTNKQVQQP
                     VMDRYQQHGMAPLTQEQKPVAKVVNDNAPQTAKEPDYLDIPAFLRKQAD"
     gene            complement(50078..51340)
                     /gene="ftsA"
                     /locus_tag="RN951_000799"
     CDS             complement(50078..51340)
                     /gene="ftsA"
                     /locus_tag="RN951_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HDX2525847.1"
                     /translation="MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSR
                     GMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEE
                     EVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
                     ITCHNDMAKNIVKAVERCGLKVDQLIFAGLASSYSVLTEDERELGVCVVDIGGGTMDI
                     AVYTGGALRHTKVIPYAGNVVTSDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVE
                     VPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEKLRQQGVKHHLAAGIVL
                     TGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLN
                     GEAEVEKRVTASVGSWIKRLNSWLRKEF"
     gene            complement(51337..52167)
                     /gene="ftsQ"
                     /locus_tag="RN951_000800"
     CDS             complement(51337..52167)
                     /gene="ftsQ"
                     /locus_tag="RN951_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ"
                     /protein_id="HDX2525848.1"
                     /translation="MSQAALNTRNSEEEVSSRRNNGTRLAGILFLLTVLTTVLVSGWV
                     VLGWMEDAQRLPLSKLVLTGERHYTRNDDIRQSILALGEPGTFMTQDVNIIQTQIEQR
                     LPWIKQVSVRKQWPDELKIHLVEYVPIARWNDQHMVDAEGNTFSVPPERTSKQVLPML
                     YGPEGSANEVLQGYREMGQMLAKDRFTLKEAAMTARRSWQLTLNNDIKLNLGRGDTMK
                     RLARFVELYPVLQQQAQTDGKRISYVDLRYDSGAAVGWAPLPPEESTQQQNQAQAEQQ
                     "
     gene            complement(52169..53089)
                     /gene="ddlB"
                     /locus_tag="RN951_000801"
     CDS             complement(52169..53089)
                     /gene="ddlB"
                     /locus_tag="RN951_000801"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDX2525849.1"
                     /translation="MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKE
                     VDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKL
                     LWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAE
                     NALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLS
                     DETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPG
                     MTSHSLVPMAARQAGMSFSQLVVRILELAD"
     gene            complement(53082..54557)
                     /gene="murC"
                     /locus_tag="RN951_000802"
     CDS             complement(53082..54557)
                     /gene="murC"
                     /locus_tag="RN951_000802"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HDX2525850.1"
                     /translation="MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGY
                     QISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDASVVVVSSAISADNPEIVAAHEAR
                     IPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAG
                     VHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFL
                     HNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLR
                     QDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFQGTGRRFDFLGEF
                     PLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYD
                     DFANVLTQVDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPARVAEML
                     APVLTGNDLILVQGAGNIGKIARSLAEIKLKPQTPEEEQHD"
     gene            complement(54611..55678)
                     /gene="murG"
                     /locus_tag="RN951_000803"
     CDS             complement(54611..55678)
                     /gene="murG"
                     /locus_tag="RN951_000803"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDX2525851.1"
                     /translation="MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADR
                     MEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGM
                     GGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGN
                     PVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQS
                     GKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPA
                     LFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQLSVDVVANTLAGWSRETLLTMAERAR
                     AASIPDATERVANEVSRVARA"
     gene            complement(55675..56919)
                     /gene="ftsW"
                     /locus_tag="RN951_000804"
     CDS             complement(55675..56919)
                     /gene="ftsW"
                     /locus_tag="RN951_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsW"
                     /protein_id="HDX2525852.1"
                     /translation="MRLSLPRLKMPRLPGFSILVWISTALKGWVMGSREKDTDSLIMY
                     DRTLLWLTFGLAAIGFIMVTSASMPIGQRLTNDPFFFAKRDGVYLILAFILAIITLRL
                     PMEFWQRYSATMLLGSIILLMIVLVVGSSVKGASRWIDLGLLRIQPAELTKLSLFCYI
                     ANYLVRKGDEVRNNLRGFLKPMGVILVLAVLLLAQPDLGTVVVLFVTTLAMLFLAGAK
                     LWQFIAIIGMGISAVVLLILAEPYRIRRVTAFWNPWEDPFGSGYQLTQSLMAFGRGEL
                     WGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYVGVVLALLMVFFVAFRAMSIGRKAL
                     EIDHRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIM
                     MLLRIDYETRLEKAQAFVRGSR"
     gene            complement(56919..58235)
                     /gene="murD"
                     /locus_tag="RN951_000805"
     CDS             complement(56919..58235)
                     /gene="murD"
                     /locus_tag="RN951_000805"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HDX2525853.1"
                     /translation="MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGL
                     DKLPEAVERHTGSLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCRE
                     AQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDDECELYVLELS
                     SFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALT
                     MPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAA
                     LALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWINDSKATNVGSTEAALNGL
                     HVDGTLHLLLGGDGKSADFSPLARYLNGDNVRLYCFGRDGAQLAALRPEVAEQTETME
                     QAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELG"
     gene            complement(58238..59320)
                     /gene="mraY"
                     /locus_tag="RN951_000806"
     CDS             complement(58238..59320)
                     /gene="mraY"
                     /locus_tag="RN951_000806"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HDX2525854.1"
                     /translation="MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRM
                     IAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVL
                     VVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLAGKDTPATQL
                     VVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWA
                     TGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGA
                     LGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWP
                     EPRVIVRFWIISLMLVLIGLATLKVR"
     gene            complement(59314..60672)
                     /gene="murF"
                     /locus_tag="RN951_000807"
     CDS             complement(59314..60672)
                     /gene="murF"
                     /locus_tag="RN951_000807"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HDX2525855.1"
                     /translation="MISVTLSQITDILNGELQGADITLDAVTTDTRKLTPGCLFVALK
                     GERFDAHDFADQAKAGGAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARV
                     VALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELG
                     ANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMN
                     ADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLP
                     LPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYN
                     ANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGEAAKAAGIDRVLSVGK
                     QSHAISTASGVGEHFADKTALITRLKLLIAEQQVITILVKGSRSAAMEEVVRALQENG
                     TC"
     gene            complement(60669..62156)
                     /gene="murE"
                     /locus_tag="RN951_000808"
     CDS             complement(60669..62156)
                     /gene="murE"
                     /locus_tag="RN951_000808"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HDX2525856.1"
                     /translation="MADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGH
                     QADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFY
                     HEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGETSAVMGTVGNGLLGKVIPTENTTG
                     SAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDM
                     EHYEAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKA
                     TEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAA
                     RLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDK
                     GKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDAGHAKVMEGRAEAVTC
                     AVMQAKENDVVLVAGKGHEDYQIVGNQRLDYSDRVTVARLLGVIA"
     gene            complement(62143..63909)
                     /gene="ftsI"
                     /locus_tag="RN951_000809"
     CDS             complement(62143..63909)
                     /gene="ftsI"
                     /locus_tag="RN951_000809"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase FtsI"
                     /protein_id="HDX2525857.1"
                     /translation="MKAAAKTQKPKRQEEHANFISWRFALLCGCILLALAFLLGRVAW
                     LQVISPDMLVKEGDMRSLRVQQVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHDAG
                     GISVGDRWKALANALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIH
                     LREESRRYYPSGEVTAHLIGFTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVI
                     EDISSTDSQAAHNLALSIDERLQALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMA
                     NSPSYNPNNLSGTPKEAMRNRTITDVFEPGSTVKPMVVMTALQRGVVRENSVLNTIPY
                     RINGHEIKDVARYSELTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKATNLG
                     LVGERSGLYPQKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSYGIYRPLSITKVD
                     PPVPGERVFPESIVRTVVHMMESVALPGGGGVKAAIKGYRIAIKTGTAKKVGPDGRYI
                     NKYIAYTAGVAPASQPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTMNIEPD
                     ALTTGDKNEFVINQGEGTGGRS"
     gene            complement(63925..64290)
                     /gene="ftsL"
                     /locus_tag="RN951_000810"
     CDS             complement(63925..64290)
                     /gene="ftsL"
                     /locus_tag="RN951_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000625658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HDX2525858.1"
                     /translation="MISRVTEALSKVKGSMGSHERHALPGVIGDDLLRFGKLPLCLFI
                     CIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIAT
                     EKLQMQHVDPSQENIVVQK"
     gene            complement(64287..65228)
                     /gene="rsmH"
                     /locus_tag="RN951_000811"
     CDS             complement(64287..65228)
                     /gene="rsmH"
                     /locus_tag="RN951_000811"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HDX2525859.1"
                     /translation="MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQ
                     LGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDL
                     GVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERF
                     AKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEE
                     IEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKL
                     GGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA"
     gene            complement(65230..65688)
                     /gene="mraZ"
                     /locus_tag="RN951_000812"
     CDS             complement(65230..65688)
                     /gene="mraZ"
                     /locus_tag="RN951_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020325403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HDX2525860.1"
                     /translation="MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIYHPC
                     LLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHA
                     GLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL"
     gene            complement(66290..67294)
                     /gene="cra"
                     /locus_tag="RN951_000813"
     CDS             complement(66290..67294)
                     /gene="cra"
                     /locus_tag="RN951_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite repressor/activator"
                     /protein_id="HDX2525861.1"
                     /translation="MKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVRE
                     HNYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQ
                     PDNEMRCIEHLLQRQVDAIIVSTSLPPEHPFYQRWANDPFPIVALDRALDREHFTSVV
                     GADQDDAEMLAEELRKFPAETVLYLGALPELSVSFLREQGFRTAWKDDPREVHFLYAN
                     SYEREAAAQLFEKWLETHPMPQALFTTSFALLQGVMDVTLRRDGKLPSDLAIATFGDN
                     ELLDFLQCPVLAVAQRHRDVAERVLEIVLASLDEPRKPKPGLTRIKRNLYRRGVLSRS
                     "
     gene            complement(67376..67462)
                     /locus_tag="RN951_000814"
     CDS             complement(67376..67462)
                     /locus_tag="RN951_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fruR/shl operon leader peptide"
                     /protein_id="HDX2525862.1"
                     /translation="MRNLQPNMSRWAFFAKSVGTWNKSSCRS"
     gene            complement(67474..67965)
                     /gene="ilvN"
                     /locus_tag="RN951_000815"
     CDS             complement(67474..67965)
                     /gene="ilvN"
                     /locus_tag="RN951_000815"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001563086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HDX2525863.1"
                     /translation="MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLS
                     RMTIQTVGDEKVLEQIEKQLHKLVDVLRVSELGQGAHVEREIMLVKIQASGYGRDEVK
                     RNTEIFRGQIIDVTPSLYTVQLAGTSGKLDAFLASIRDVAKIVEVARSGVVGLSRGDK
                     IMR"
     gene            complement(67968..69692)
                     /gene="ilvI"
                     /locus_tag="RN951_000816"
     CDS             complement(67968..69692)
                     /gene="ilvI"
                     /locus_tag="RN951_000816"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020079613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 3 large subunit"
                     /protein_id="HDX2525864.1"
                     /translation="MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGID
                     HVLVRHEQAAVHMADGLARATGEVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQ
                     VATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVD
                     LPKDILNPANKLPYVWPESVSMRSYNPTTTGHKGQIKRALQTLVAAKKPVVYVGGGAI
                     TAGCHQQLKETVEALNLPVVCSLMGLGAFPATHRQALGMLGMHGTYEANMTMHNADVI
                     FAVGVRFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVTADIPIVGDARQVLEQMLEL
                     LSQESAHQPLDEIRDWWQQIEQWRARQCLKYDTHSEKIKPQAVIETLWRLTKGDAYVT
                     SDVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGS
                     IQMNIQELSTALQYELPVLVVNLNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLA
                     EAYGHVGIQISHPHELESKLSEALEQVRNNRLVFVDVTVDGSEHVYPMQIRGGGMDEM
                     WLSKTERT"
     gene            69811..69855
                     /locus_tag="RN951_000817"
     CDS             69811..69855
                     /locus_tag="RN951_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2525865.1"
                     /translation="MKRNDKILHYRGLN"
     gene            complement(70010..70954)
                     /gene="leuO"
                     /locus_tag="RN951_000818"
     CDS             complement(70010..70954)
                     /gene="leuO"
                     /locus_tag="RN951_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414618.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LeuO"
                     /protein_id="HDX2525866.1"
                     /translation="MPEVQTDHPETAELSKPQLRMVDLNLLTVFDAVMQEQNITRAAH
                     VLGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARAFQLFGSVRQALQLVQNELPG
                     SGFEPASSERVFHLCVCSPLDSILTSQIYNHIEQIAPNIHVMFKSSLNQNTEHQLRYQ
                     ETEFVISYEDFHRPEFTSVPLFKDEMVLVASKNHPTIKGPLLKHDVYNEQHAAVSLDR
                     FASFSQPWYDTVDKQASIAYQGMAMMSVLSVVSQTHLVAIAPRWLAEEFAESLELQVL
                     PLPLKQNSRTCYLSWHEAAGRDKGHQWMEEQLVSICKR"
BASE COUNT        17474 a        19286 c        17257 g        17173 t
ORIGIN      
        1 accatacctt cctgatgggg cagaatgcat ctaatattga tctcagccgg tacagtgaag
       61 gtaaccccgc tataccgggt gtttacgacg tcagtgttta tgtaaacgac caaccaatca
      121 ttaaccaaag tattacattt gtcgcaattg aaggaaaaaa gaacgcccag gcttgtatca
      181 cattaaagaa tttattgcag tttcatatta attctcccga tataaataac gaaaaagccg
      241 ttctgcttgc cagggatgaa acgctcggca attgcctcaa tttgacggaa attatccctc
      301 aggcttctgt tcgttatgac gttaacgatc aacgtctgga tatagacgtt cctcaagcct
      361 gggtaatgaa aaattaccaa aactatgttg atccatcgtt atgggaaaac ggcattaatg
      421 cggccatgtt gtcatacaac ctcaacggat atcatagtga aacccctggt cgaaaaaatg
      481 aaagcattta tgctgcattt aacggtggga tgaatttagg tgcatggcga ctgcgtgcct
      541 cgggcaacta caactggatg accgattctg gcagtaatta tgattttaag aatcggtatg
      601 ttcagcgtga tatcgcctcg ctgcgttctc aactcattct tggtgagtct tatacgacgg
      661 gcgaaacctt tgattccgtc agtatccgag gcattcgttt atacagtgac agccgcatgt
      721 tgcctccgac tttagccagc tttgcgccta tcattcatgg cgttgccaat accaacgcca
      781 aagtcactat tacgcaaggt ggctataaga tttatgaaac gacggtgccg ccaggcgctt
      841 tcgtcattga tgatctgagt ccgtcagggt acggcagcga tcttattgtt accatcgaag
      901 aatccgatgg ctcaaagcgg acattctcgc aacctttctc atccgttgtt caaatgttac
      961 gccctggcgt tggacgttgg gatattagcg gcggtcaggt cttaaaagat gatattcagg
     1021 atgagcctaa tttatttcaa gcaagctact actacggcct gaataactat ctgacgggtt
     1081 ataccggtat tcagataacc gataataact ataccgctgg tttgttaggt cttggtctga
     1141 atacttcagt tggtgcattt tctttcgatg tgactcattc caatgttcgt atcccggatg
     1201 ataaaacata ccaggggcaa agttatcgtg tttcctggaa caagttattc gaagaaacaa
     1261 gtacttcact gaatatcgcg gcctatcgct attcgacaca gaattacctt ggtcttaatg
     1321 atgcactaac tctaattgat gaagtgaaac atcccgaaca agatcttgaa ccgaaattca
     1381 tgcgtaatta ctcacgcatg aaaaatcagg ttacggtcag tattaaccaa ccgttgaaat
     1441 ttgagaaaaa agattacggt tcattttatc tttccggaag ttggtccgat tactgggctt
     1501 ccggacaaaa tcgtagcaat tactctattg gctacagtaa cagtacatcc tggggcagct
     1561 acagtgtcag tgcccagcgt tcatggaatg aagacggcga cactgacgat agcgtttatc
     1621 ttagtttcac cattccaatt gaaaaattac ttggcactga acaacgtact tcaggtttcc
     1681 agagtattga tactcaaata agcagtgact ttaagggtaa taaccaactc aacgttagca
     1741 gcagtggcta tagcgataac gctcgcgtca gttatagcgt gaatactggc tatacgatga
     1801 ataaagccag caaagatttg agttatgttg ggggttatgc cagctatgag tcaccatggg
     1861 gaacgctggc aggttcaatt tctgcaaata gcgataacag ccgtcaagtt tctctcagca
     1921 ccgacggtgg ttttgtattg catagcggtg gactgacttt cagtaatgat agttttagcg
     1981 actccgatac actggcggta gttcaagctc caggtgctca aggagcgcga ataaattatg
     2041 gcaacagtac tatcgatcga tggggttatg gtgtcaccag cgctctttct ccttatcatg
     2101 aaaaccgtat cgcgctggat atcaacgatc ttgagaacga tgttgaatta aaaagtacca
     2161 gtgcagtagc tgtaccgcgt cagggttcag tcgtctttgc tgattttgaa accgtgcaag
     2221 ggcaatcagc cattatgaac atcacacgaa gtgatggtaa aaatattcca tttgctgcag
     2281 atatttatga tgagcaaggc aatgtcattg gtaatgttgg acagggtgga caagcatttg
     2341 ttcgtggtat tgagcagcag ggaaatatca gcattaaatg gctcgaacaa agtaaacccg
     2401 taagttgtct tgcgcattat caacaaagcc cagaagcaga aaaaatagca caatctatta
     2461 ttctgaatgg aattcggtgt cagattcagt aactacaagg gacgtcaaat gataaaaaca
     2521 acgccacata aaatagtgat actgatggga atattattat caccctcagt atttgcaacg
     2581 gatattaatg tagagtttac agccactgtc aaagcgacaa cctgtaacat cacacttact
     2641 ggtaataacg tcacgaatga tggcaataat aactacacat tgagaatccc taagatgggt
     2701 ctggataaga tcgcgaataa aacgacagaa tctcaggctg attttaaact ggttgccagt
     2761 gggtgcagca gtggcatcag ttggattgat accactctga ccggaaatgc atcatcaagc
     2821 tcacctaagc ttattatacc gcagtctggt gattcatctt cgacgacaag taatatcggt
     2881 atgggtttca aaaaacggac tactgatgat gccactttcc ttaaacctaa cagtgcggaa
     2941 aagatacgct ggagcacaga cgagatgcag cccgataagg gtcttgaaat gaccgttgcg
     3001 ctacgtgaaa cagatgcagg gcaaggcgta ccggggaatt ttcgtgcact ggcgacgttt
     3061 aatttcatct atcaataaga aggataatta tgatgacatt taaaaattta cgttatggat
     3121 tatccagcag tgtcgttttg gctgcctcat tgttcagcgt actctcttat gcggcaacag
     3181 acagtattgg actgaccgtt attactactg tagaaatggg tacttgtacc gctacattag
     3241 taaatgactc tgatcaggac atttctgttg ttgattttgg tgatgtatat atttctgaaa
     3301 tcaatgccaa gaccaaagta aaaacattca aactcaaatt caaagactgt gcgggtatcc
     3361 ccaataaaaa agcgcaaata aaattaacca agcgagccac atgcgaggga actgctaatg
     3421 acggtgcggg gtttgcaaat ggttccacag ccgcagataa agcaagtgct gtcgccgttg
     3481 aagtctggag cactgtaact ccggcaacag ggagtgcaac acaatttagc tgtgtaacac
     3541 cagcatcaca agaggtaaca atctccactg cagccaatgc ggtcgtttat tatccgatga
     3601 gtgcacgcct ggtcgtggaa aaaaataaaa ccgtaaacaa tgtcactgcg ggtaagtttt
     3661 ctgcaccagc cacatttaca gtaacctata actaacagac ttacagattc aggaactata
     3721 tatgcatccc actcaacgta agctgatgaa gagaataatt ctgtttctgt cattactgtt
     3781 ttgcatcgcc tgtccagcca ttgctggaca ggatattgac cttgttgcca atgtaaaaaa
     3841 cagcacctgc aaaagcggaa tcagtaacca gggtaatatt gatcttggcg tcgttggggt
     3901 gggatatttt tcaggtaatg ttactcctga aagttatcaa ccaggtggaa aagagttcac
     3961 tatcactgta tccgactgtg cattacaggg aactggcgat gtgctaaatc agttacatat
     4021 tgattttaga gcccttagcg gtgtcatggc tgctggctct aggcaaatat ttgctaatga
     4081 aatttcgtca ggagcaagta atgtaggagt agttatattt tctactcagg attcggcgaa
     4141 tacattcaat gttcttaatg cttcaggcgg atctcgttcc gtttatccag taatgtcgga
     4201 tgacatgaat ggttcatcct ggaaatttag cacccgaatg caaaaaatcg atcctgcatt
     4261 gagtgttaca tctggtcaac ttatgagcca tgtgttagtg gatatttact acgaataaca
     4321 aacaaaaaca gcgcaaacca taacaataaa gaaacattgg agtaaaaatg aagactatct
     4381 tcaggtacat tcttttttta gcactgtatt cttgttgtaa tacagtcagt gcatatacaa
     4441 gttttattgt gggaaataat gcaggagttg ataactatcg aggcccctcc actgccgcac
     4501 agatgacctt taattacaca tcaacagcaa gcaacttggt tttttataaa cccacgcagc
     4561 tcggcccgac tggggtaaaa atgtactggt catacctgga tacaggtacc ggtggtggta
     4621 ttctttactg caatacatct ggcagagcga atcctggtcc aataactatt gaaaatgcca
     4681 tggtctattc atggtaaaga ttatggcgga cataaactat ttaatacatc tgttcctggt
     4741 ctgtattaca ccatgttaat atcaagggtc tggtctgcat acgatacaat aactgacatt
     4801 caatcgccag gaatctatat cggagatcct tccaaccaag aatttttctt ttccgtcaca
     4861 gacagcgatc tacaaactaa gggttgcaac aaagcagacg actacgataa gttttgggct
     4921 attggtggta tagtacacaa cataactgtt gaattttata cagatactaa tttcgatcct
     4981 acacttaatc agcaagtcca gttatccagt tcatcaaatt acctttattc gtttaaggcc
     5041 tacagtcctg gtacaaaagt tgtagatcac agcaaccaca tttatgtcaa tttcacactg
     5101 aataatgtca aattaacctt accaacatgt tttacctcca tacttaccgg gccatcagtc
     5161 aatggttcaa cggttagaat gggagaatat agctctggga caattaaaaa tggcgcttca
     5221 cctgttccct ttgatatctc gcttcagaat tgtattcgtg tgcgtaatat tgaaacaaaa
     5281 ctcgtcactg gaaaagtagg tactcaaaac acacaactgc ttggtaatac gcttactgga
     5341 agcactgccg ccaaaggcgt tggcgtactc attgaaggtt tagcaaccag taaaaatccg
     5401 ctaatgacat taaaacctaa tgatacgaat tctgtttata tagattatga aaccgaagat
     5461 gacacctccg atggggttta ccctaatcaa ggtaacggca catcacagcc tcttcatttc
     5521 caggcaacat taaagcaaga cgggaatatt gctatcgaac ccggcgaatt taaagccacc
     5581 agtactttcc aggtaaccta tccctgataa cgtagcagca ctgtcacctt ctggcagtgc
     5641 tgctacggat aaatcattgc ccccaccaat gtgactgata aaatgccaga cagcacaaca
     5701 tcaatttatc aggatacgtt atgaaaccga ccaccatctc cttactgcag aagtacaaac
     5761 aggaaaaaaa acgtttcgcg accatcaccg cttatgacta tagcttcgcc aaactctttg
     5821 ctgatgaagg gcttaacgtc atgctggtgg gcgattcgct gggcatgacg gttcaggggc
     5881 acgactccac cctgccagtt accgttgccg atatcgccta ccacactgcc gccgtacgtc
     5941 gcggcgcacc aaactgcctg ctgctggctg acctgccgtt tatggcgtat gccacgccgg
     6001 aacaagcctt cgaaaacgcc gcaacggtta tgcgtgccgg tgctaacatg gtcaaaattg
     6061 aaggcggtga gtggctggta gaaaccgtac aaatgctgac cgaacgtgcc gttcctgtat
     6121 gtggtcactt aggtttaaca ccacagtcag tgaatatttt cggtggctac aaagttcagg
     6181 ggcgcggcga tgaagcgggc gatcaactgc tcagcgatgc attagcctta gaagctgctg
     6241 gggcacagct gctggtgctg gaatgcgtgc cggttgaact ggcaaaacgt attaccgaag
     6301 cactggcgat cccggttatt ggcattggcg caggcaacgt cactgacggg cagatcctcg
     6361 tgatgcacga cgcctttggt attaccggcg gtcacattcc taaattcgct aaaaatttcc
     6421 tcgccgaaac gggcgacatc cgcgcggctg tgcggcagta tatggctgaa gtggagtccg
     6481 gcgtttatcc gggcgaagaa cacagtttcc attaaggagt cacgttgtgt taattatcga
     6541 aaccctgccg ctgctgcgtc agcaaattct ccgcctgcgt atggaaggca agcgcgtggc
     6601 gctggtgcct accatgggta acctgcacga tggccatatg aagctggtcg acgaagccaa
     6661 agcccgcgcc gatgtggtcg tcgtcagtat tttcgttaac ccgatgcagt tcgaccgccc
     6721 ggaagatctg gctcgttatc cacggacctt gcaggaggac tgcgagaagc taaacaaacg
     6781 taaagtggat ttagttttcg ccccttcggt aaaagagatc tacccgaacg gtactgaaac
     6841 ccacacttac gttgacgttc ctggcctttc gaccatgctg gaaggtgcca gccgtccggg
     6901 acattttcgc ggcgtttcga ctattgtcag caagctgttc aacctggtcc agccggacat
     6961 cgcctgcttc ggtgaaaaag attttcagca actggcgctg atccgcaaaa tggttgccga
     7021 tatgggcttc gatattgaga ttgtcggtgt gccaattatg cgcgccaaag acggtctggc
     7081 gctaagttcc cgtaacggtt atctgacggc ggaacaacgc aaaattgcgc ctggtctgta
     7141 caaagtttta agttcgattg ctgacaaatt gcaggctggg gaacgggatc tcgatgaaat
     7201 tattaccatt gcggggcaag aactgaatga aaaaggcttc cgcgccgatg atattcagat
     7261 tcgcgatgcc gacacattgc tggaagtttc tgaaaccagc aaacgggcag taattctggt
     7321 agccgcctgg cttggcgatg ctcgcctgat cgacaacaaa atggtcgagc tggcgtaata
     7381 cttaactggc gctacggctg atggcgccag ttattaattt accccacgtc atctgtcata
     7441 acacaggtaa cttaaataag gttaattacc ttatcaatct cagcaagagg taaatttgcc
     7501 atctctgcaa cgtcttcccg agacattcct ttactcagaa gacgctgggc gaattcctga
     7561 cttacttcct gtcttccctg ctgaatcccc ttctcaatcc ctttctcttc aaaccactgc
     7621 gccagcgtca tcatagactc ccctcccgtt tccctgtctc tcaacacacc gtaaaacaaa
     7681 tccgcttgtt cagtatgacc gcgttgcagc atatagtttt gcatggcaac taactgactt
     7741 ccgctagtgt acccttcgtc gatcagcgtg accagttgct caagcaataa cattaagtcg
     7801 cgctggcgaa tatgtttttg cagtagttcg agaatcgcaa tccgccgatg ttgcatgatt
     7861 tcgtcatccg gtgtgatggt gatatccacc agcgggaaag gactgttata gacgcgtcgc
     7921 gccagctccg gcgagtaaaa catatcaaac cagcacattg atagcggata aggtgtggcc
     7981 tcgccctgat aaaacagtat cggcaccacc agcggcagct tatcgtggtc agcctccaga
     8041 tgccggtgca tggcggctat agaataacgc atcatgcgaa aggccatttt cttatccggc
     8101 ttgctttggt gttcaatcac aacatgcaga taaccgggat tgccctgcat ttgcacggaa
     8161 tagagcacgt ccgtgctgtg tcctttcagg ctctcttcaa tgaaactccc cgactctaaa
     8221 tgaagcgtgt tgaggtcaca aagttcgcgt aattccactg gcaaatgtat ctccagaaag
     8281 tcgcgagccg tctccgcatg cattaaaaat tgtttaaata ccgcgtcatg cggtgtggta
     8341 ctcggtgcat ccatcttccc tgtcttccgt gtggctttgc gtgaaggcag tatccagtca
     8401 aggcgcgcta tcgtcagcca cctctttatt gtttaccgag cagcgttcag agaaatatca
     8461 attcgttaca ggcgatacat ggcacgcttc ggcgcggtac gcaaactgct gacgcaaatg
     8521 ccgtcagatg agtagacact aaacaaaaat cgggcaatac tgcgtgagaa tttcctcaaa
     8581 gcaggcatcg cctgcttcgt taacgacagg gtagaaaggt agaagttatg attcgcacga
     8641 tgctgcaggg caaactccac cgcgtgaaag tgactcatgc ggacctgcac tatgaaggtt
     8701 cttgcgccat tgaccaggat tttcttgacg cagccggtat tctcgaaaac gaagccattg
     8761 atatctggaa tgtcaccaac ggcaagcgtt tctccactta tgccatcgcg gcagaacgcg
     8821 gttcgagaat tatttctgtt aacggtgcgg cggcccactg cgccagtgtc ggcgatattg
     8881 tcatcatcgc cagcttcgtt accatgccag atgaagaagc tcgcacctgg cgacccaacg
     8941 tcgcctattt tgaaggcgac aatgaaatga aacgtaccgc gaaagcgatt ccggtacagg
     9001 ttgcttgatt gttatccctg cggctggtta ctcaccagcc gcgacatcgt ctccagcgaa
     9061 tccgttctta agatataaag tcgttttagt aacaacggat tatcccccgg ttttactttg
     9121 cctttcatgg ttgtcaccgc caggtgaaat ccggcatcgt ttgctgcctt cacggcgttg
     9181 tcattaaatc cgccaaacgg atacgaaaga taccagacat gcggattaaa ttgcgccaga
     9241 gcgcggcgtg aacgtgcaaa atcaaacaga atattgtgct cactacggct cagtaatatg
     9301 ggtcggcgat aaccatctac ccgatgcaaa aaatgggtat gtgactggaa atcaaataca
     9361 tcgcgaattt cgttaagctc agaaacgctc ataaattgca gcgattttgg gttccacttc
     9421 tgcgggtgac gtttgatgcg tgaggtaaca ataaacgccg tcgccttcat gccatattgt
     9481 ttcaacacag gatacgcata gcggctcacc gacttgaggc catcatcaaa ggtaatcacc
     9541 accgctcgcg cagggagatt gatcttattc ttcacgtagc cttccagctg caccatgctc
     9601 agtgtcgcgt atcccctgtc acgcagccag gccatctggt tattgaaagc gcgtaccgat
     9661 gtggtcgtcg aagtatggcg aaaacgggtg ttttcttcgt cgcgcagaat atggtgatag
     9721 gttagcaccg acaggccatt atcgggttgg gcatccagtg cgctgatata ggccagtcga
     9781 tcgccaatac ggatctgata ccaggtttga tttaacctgt ctttcagttt atgcaaaatc
     9841 gggtagcgca aattgtccgc cagtacccca aatggcgcac ttcccgcact cggcgcgtta
     9901 tagaccggcg tatctttcca ggtaactaag ttctgattac tcagcggctt gttgaggtcg
     9961 cccaaaccgt cttcaacttt ttgtcgcccc tgaaccggct cgagatgacc tttatcgata
    10021 aaacctttgc caaagccaaa attaaatgcg taataacttg cggcagtggg ctccacggca
    10081 atgatttgtc cggcccgaat attccccacg gtcaccatct tgtcaccaat ttgcgcccag
    10141 accgcagcat tttcgatggt ttgcatataa cgggcaggta acgcggcact gacacttgcg
    10201 gtaaacagca tcagcaggag aataacagct tgtttgtaca tgaaaaaata accgagggtg
    10261 aaacaacgct tttattgtag caaaagcgcc atcagaatcg cgggttaata ctcatacaaa
    10321 ttatgtttga ggacgaaagg cggatttttt tgttgttggt gccaaagact actcacctcc
    10381 ggcgcaccca gttcgacaat acgctcgcga aactctgaac tggtcatggt ttcacggcaa
    10441 gccatcatct gttcaattaa cggtaacgtg acaccagaaa tcacttcgca acgggagtgt
    10501 ttgtggctta ataatgaagc cacgcgatac ggtggcgctc cggctatatc ggttaagaag
    10561 atgacaccct caccagagtc cgcttcatgc agagcatcgc acatcatgcg gctgagcata
    10621 ttagagctta atccgcgcca gaaattcacg gcccggcact gaagaagtgc cccatgtttt
    10681 ttctccagcg catccagtat ctcttgcgcc cggtcatcgt gacaggtaat tacccaacct
    10741 aacatcgcct tcctccttag ccgaaaatca gtctaccctg accattgttg ataaagggtg
    10801 atagccgtca aaactcctct cccccaaatc cagaggagag gaaatagcct tagctacgca
    10861 aaccacgtcc acgttggatc agcgaccaac agatcaaata aaacgccaca ataaagacca
    10921 ccagtacgcc aaaggtagtg accagcggaa catcattgat accgaggaag ccgtagcgga
    10981 aaccactgat catataaacg attgggttca ggtgcgacag cccttgccag aacggcggca
    11041 acaaagtcag tgagtaaaag accccgccca aatacgtgag tggcgttaac acaaaggttg
    11101 gcaccaggct gatgtcatcg aacgttttgg caaacacacc gttcagcaaa cccgcaaggg
    11161 agaacaacac cgccgtgagc accagcgtta aggcaacgaa tacccacgaa tgcacctgaa
    11221 atggcacaaa aaacagtgaa attgccgtca ccagaatgcc aacaaacaga ccacgcgcca
    11281 cgccaccgcc gacatatccg gcaataatga cgtgagtcgg aaccggcgct accagcagct
    11341 cttcaatatt acgctggaac ttggcaccaa aaaatgatga cgcaacgttg gcgtaggcat
    11401 tggtgatcac cgacatcatg atcagccccg gtacgatgaa ctgcatatag ctgaagccat
    11461 gcatatcgcc aatacgcgaa ccaatcaggt taccgaagat aataaagtaa agggtcatgg
    11521 tgatgactgg cggcaccagc gtctgcaccc agatacgcat aaagcgatgg atctctttcg
    11581 cccagatgct ttttagcgcc acccagtaaa gatgcatcat gcgcgatctc cttgtttttc
    11641 attaaccagt gaaacaaaca gctcttccag acggttagct ttgttacgca tacttaatac
    11701 ctgaatgccc tgctcactta actgcgtaaa tacgctgttg atcccctgct cacgcagcac
    11761 ttcaacttcc agcgtcgcgg tatcgaccag tcgatactga tagccatcga gcttcggtaa
    11821 cgggcttttc ggtgcgagat cgagaataaa ggtttccgat ttcagcttcg ccagcagcgc
    11881 cttcatcgag gtattttcca ccagctcacc gtgttgaata atgccgatat tgcggcacag
    11941 catttctgct tcttccaggt agtgtgtggt gagaatgatg gtggtgcctt tgtcgtttaa
    12001 atccttcaaa aagccccaca ttgagcggcg aagttcaata tccacgcctg cggtcggttc
    12061 gtcgagaatc agtagtttag gttcatgcat taacgcacgg gcaatcatta aacggcgctt
    12121 catcccgcca gataacatac gcgcacgttc gttgcgtttt ccccatagat cgagttgttt
    12181 aagatacttt tcgctgcgga tgtacgcttc tttgcgctcc acgccgtagt accctgcctg
    12241 attcaccaca atttgctgca cggtttcaaa cgggttgaag ttaaattcct gcggcaccag
    12301 tcccaactga cgtttagcgt tcacgacatc cttctcgaga tcgtaaccaa atacgctgac
    12361 ccgcccggag gttttattta ccagagagct gataataccg atagtggtcg atttcccggc
    12421 cccgttcggc ccgagaagcg cataaaaatc acccgcttcg acctgcaaat ctatcccacg
    12481 aagcgcctga acgccgcctg gataggtttt tttaagctgt tgaagttcca gtgcaatggt
    12541 cataaatttt tacttacctt acgttcttac actttatctg tggtttaaat cgtcccggag
    12601 ttgccctata ttagccaaac gtaattattt ggttacaggt cgttaacctc catgaaagac
    12661 atagatacac tcatcagcaa caatgcacta tggtcaaaaa tgctggtgga agaggatccc
    12721 gggttttttg agaaactggc acaagcgcaa aaaccgcgct ttctatggat tggatgttcc
    12781 gacagtcgcg ttcctgcaga acgtttaacc ggtcttgagc cgggcgaact ctttgttcac
    12841 cgtaatgttg ctaacctggt cattcacact gacctgaact gcctttccgt ggttcagtat
    12901 gcagtggatg tactcgaagt tgaacacatt attatctgtg gccactacgg ttgcggcggc
    12961 gtacaagccg cagttgaaaa cccggaactg gggcttatca acaactggct gctgcatatc
    13021 cgcgatatct ggttcaaaca tagctcattg ctcggcgaaa tgccgcaaga gcgccgtctg
    13081 gataccttgt gtgaactgaa cgtcatggaa caggtgtata acctgggcca ctccaccatt
    13141 atgcaatcag cgtggaaacg cgggcagaaa gttaccattc acggctgggc ctacggcatt
    13201 cacgacggct tgctgcgtga tctggatgtt accgccacca accgcgaaac ccttgagcaa
    13261 cgttaccgtc acgggatttc caacctcaag ctgaaacacg ccaaccacaa ataaaaatgc
    13321 catgccggat gcaacacatc cggcaacttc acacttactc gtccagcaga atcactttgc
    13381 cgatatacgg cagatgacgg taacgctgtg cgtaatcaat gccgtaaccc accacaaact
    13441 catccgggat cgagaaaccg ataaattcta ccgggacgtt cacttcacga cgggacggtt
    13501 tatccagcag cgtacaaatc gccagcgact tcggttcgcg caggcttaag atctcacgca
    13561 ctttcgacag tgtattcccc gagtcgatga tatcttcaac aatcagcacg tccttgccac
    13621 ggatatcttc atccagatct ttgaggattt tcacatcacg ggtggtggac atgccgctac
    13681 cgtagctgga ggcggtcata aagtcgactt catgagatac ctgaacttca cggcacaggt
    13741 ccgccataaa cataaatgag ccacgcagca gacccaccag caccatatcg ctgccgctgt
    13801 ctttgtaacg ctcagtaatc tgacgaccca gttcggcgat acgcgcttta atctccgctt
    13861 cggggatcat tacttctaca gtatgtttca tatctctaac catatgattt aaaaacaaat
    13921 cacttcgcac gggcaggttt tggcaccgca acaaagcgca agacacgcag tataccagta
    13981 aaactattca ttcgcggaat ctgttaataa agctcgaatt gtgatgacga tcacacatgt
    14041 taaaacctat aattaattgc tactaaaata ttaatgaatt gaaatggtgt ctctttatgg
    14101 caattaacaa tacaggctcg cgacgattac tcgtcacgct aacagccctt tttgcagcgc
    14161 tttgcgggct gtatctactc attggcggag gctggctggt cgcgattggc ggctcctggt
    14221 actaccctat cgctggcctt gtgatgctcg gcgtcgcctg gatgctgtgg cgcagtaaac
    14281 gcgccgcgct ttggctatac gcagccctgc tgctcggcac catgatttgg ggcgtctggg
    14341 aagttggttt cgacttctgg gcgctgactc cgcgcagcga cattctggtc ttcttcggca
    14401 tctggctgat cctgccgttt gtctggcgtc gcctggtcat tcctgccagc ggcgcagttg
    14461 ccgcactggt ggtcgcactg ctgattagcg gtggtatcct gacctgggcc ggatttaacg
    14521 atccgcagga gatcaacggc accttaagcg ccgatgccac acctgctgaa gctatctccc
    14581 ccgtagccga tcaggactgg cctgcctatg gtcgtaatca ggaaggtcaa cgcttttcgc
    14641 cgctgaaaca aattaacgcc gataacgtcc ataatctgaa agaagcctgg gtgttccgta
    14701 ctggcgatgt gaagcagccg aacgatccgg gtgaaatcac caatgaagtg acgccgatta
    14761 aagtgggcga caccctttac ctgtgtaccg ctcaccagcg cctgtttgcg cttgatgccg
    14821 ccagcggcaa agagaaatgg cattacgatc ctgagctgaa aaccaacgag tctttccagc
    14881 acgtaacctg ccgtggtgtc tcttatcatg aagccaaagc agaaaccgct tcgccggaag
    14941 tgatggcgga ttgcccgcgt cgtatcattc ttccggtcaa tgatggtcga ctgattgcga
    15001 ttaacgctga aaacggcaaa ctgtgcgaaa ccttcgccaa taaaggcgtg ctcaatctgc
    15061 aaagcaatat gccagacacc aaaccgggtc tgtatgaacc gacttcgcca ccgattatca
    15121 ccgataaaac catcgtgatg gccggttcag ttaccgataa cttctcaacc cgcgaaacgt
    15181 ctggcgtgat ccgtggtttt gatgtcaaca ccggggagct gctgtgggct tttgatcccg
    15241 gcgcgaaaga tccgaacgca atcccgtctg acgaacacac ctttaccttt aactcgccaa
    15301 actcctgggc accagcggcc tatgacgcga agctggatct ggtctatctg ccgatgggcg
    15361 tgaccacgcc ggatatctgg ggcggtaacc gcacaccgga acaggaacgt tatgccagct
    15421 cgattctggc gctgaatgcc actaccggga aactggcgtg gagctaccag accgttcacc
    15481 acgacctgtg ggacatggat cttccggcac agccgacgct ggcggacatc accgttaatg
    15541 gtcagaaagt gccagttatt tacgctccgg cgaaaaccgg caacattttt gtgctcgatc
    15601 gtcgtaatgg cgaactggtg gttccggcac cggaaaaacc ggttccccaa ggtgcagcga
    15661 aaggcgatta cgtaacccca actcaaccgt tttctgaact gagcttccgt ccgacgaaag
    15721 atttgagcgg tgcggatatg tggggagcca ccatgtttga ccaactggtg tgccgcgtga
    15781 tgttccacca gatgcgctat gaaggcattt tcaccccgcc atctgaacag ggtacgctgg
    15841 tcttcccggg taacctgggg atgttcgaat ggggcgggat ttccgttgat ccaaatcgtg
    15901 aagtggcgat tgccaaccca atggcactgc cgtttgtttc gaaactgatc ccgcgtggtc
    15961 ctggcaaccc gatggagcag ccgaaagatg ccaaaggcac aggtacggaa tccggcattc
    16021 agccacagta cggtgtaccg tatggtgtca cgctcaaccc gttcctctca ccatttggtc
    16081 tgccatgtaa acagccagca tggggttata tctcggcgct ggatctgaaa actaatgaag
    16141 tggtgtggaa gaaacgtatt ggtacgccgc aggacagtat gccgttcccg atgccggttc
    16201 cggtgccgtt caatatgggt atgccgatgc tgggcgggcc aatctccacg gcgggtaacg
    16261 tgctgtttat cgccgctacg gcagataact acctgcgcgc ttacaacatg agcaacggtg
    16321 aaaaactgtg gcagggtcgt ttaccagcgg gtggtcaggc tacgccaatg acctatgaag
    16381 tgaatggtaa gcagtatgtg gtgatctccg caggcggtca cggttcattt ggtacgaaga
    16441 tgggcgacta tattgtggct tatgcgctgc cggatgatgt gaagtaagac ttgctcagat
    16501 tgctgacaac gtgcgcgttg ttcatgccgg atgcggcgtg aacgccttat ccagcctaca
    16561 aaattgtgca aaatcaatgg attgcacagc tagcgtaggc ctgataagcg tagcgcatca
    16621 ggcagatttg cgtttgtcat cagtttaatg cccggagaga tccgggcata tttccgaata
    16681 cggtcttttt ataccgtaaa ccctaacatc atccccgtat cttcatgctc cagcagatgg
    16741 cagtgcgcca tataagcatg ttctttcggt gcatcgtgat taaacttcac cagcacttcg
    16801 ctgacattac cttctacctt aacggtatct ttccagcccg cgcgatgagc cgctggcggt
    16861 ttgccatttt ctgacaagat acggaactgc gtgccgtgga tatggaacgg atgcagcatc
    16921 atgtcgccca cgccagagat aacccaacgt tcgtattgcc ctttcgccgc cgcaaacatc
    16981 ggcttgttca tatcaaacgc ctgaccgttg attttgttgg catggtggaa atcgaacttc
    17041 ccgccgtggt tcatatgatt catattgccg tgccccatat ggcccatcat ctggctgtga
    17101 tccatcccgg ccatcgcctg atcgccatat ttctccatta gcatctgcat ccccatcata
    17161 tcgagcatcg ggtccataga gagttgcagc ttgcgtaccg tcagcccttc cagcgaaggt
    17221 aacgcaggca ggctacttaa tgtgtctggc aaagcaccgg aggcactaat agcaatcggc
    17281 tgaatccgca ttaccggatg aggcttatca aacggcgcaa tcgccatccc catctggctg
    17341 accggcagcg tcaccaggtc aaagggtttg ttatcgttaa cctccaccag cacttcaaaa
    17401 cgctcgccca tcagcaccgg cagttcgctc accttcactg gttcaggtag cagaccaccg
    17461 tcgctggcaa tcacatacag cgggcgattg tcgctggtgg cgaaattgag cgaacgggca
    17521 ttacagccat tgagcaaacg caggcgcagc caaccacgcg gggcagcgtg ttgcgggtag
    17581 attgcaccgt tggtcagcaa cgtatcgcca aaccagccca cggcggcggt catcacatcc
    17641 agttgataat caatctgccc gtcggcgcta aatttcttat cctgaacgat caccggaaca
    17701 tcatcgatac cccactgttt tggcagcatt aatttcagga tctcgtcatc ttcaatcacc
    17761 accagcccag ccagccccat cgccacctgt cgcccggttt tgccgtgctg atgcggatgg
    17821 aaccagcagg tagcggcagg ttgatcaacg ttcaacgtca ccgagcgctt gccacctggc
    17881 ggaataattc cctgcgggcc gccgtcgact tcacccggta cttccagccc gtgccagtgc
    17941 aacgttgtct cttccgtcag ttggttgtag atatcaaccg ttaccgcttt gccgcgctgt
    18001 aatttcaccg ccggccccag cagattgccg ttatagcccc aggtagttgc agttttcccg
    18061 ccaaaggtgg actggcctgc gccaatagtt aactgaatgc gattacgggc atcggtcgtg
    18121 agcaaatcag ggatcggtaa cgttgggcgt tctgccgcaa atactgcgcg gctccacagc
    18181 ggcaaagccg aagccacacc cagcgcgacg gaatatttta agaaatcacg acgttgcata
    18241 gttatttcct tattcttaag caggcgaaac aaaatcaaac gttgagcata gtccttcccc
    18301 ttacgggaag gtcaagccgc agacacaatt taatcgacaa taatggtcgt cgcctcgctc
    18361 gcagtgtgct aacgtttatc ttctttaagc ccctggtaga agcaatgaag acgtttttca
    18421 gaacagtgtt attcggcagc ctgatggccg tctgcgcaaa cagttacgcg ctcagcgagt
    18481 ctgaagccga agatatggcc gatttaacgg cagtttttgt ctttctgaag aacgattgtg
    18541 gttaccagaa cttacctaac gggcaaattc gtcgcgcact ggtctttttc gctcagcaaa
    18601 accagtggga cctcagtaat tacgacacct tcgacatgaa agccctcggt gaagacagct
    18661 accgcgatct cagcggcatt ggcattcccg tcgctaaaaa atgcaaagcc ctggcccgcg
    18721 attccttaag cctgcttgcc tacgtcaaat aatccctgat acctttttgt agaaatattg
    18781 accgtgcatc cgcggtcaat gttagctatt atgttgcgcc ctttttttac gggtgttaac
    18841 aaaggaggta tcaacccatg gccgaaaaaa aacagtggca tgaaacgcta cacgaccagt
    18901 ttgggcagta ctttgcggta gataacgttc tgtatcatga aaagaccgat caccaggatc
    18961 tgatcatttt tgagaacgct gcatttggtc gcgtaatggc gctggatggc gtagtacaaa
    19021 ccaccgagcg cgacgagttt atctatcatg agatgatgac ccatgttccg ctactggccc
    19081 atggtcacgc gaaacatgtg ctgattatcg gcggcggcga cggtgccatg ctgcgtgaag
    19141 taacccgaca taaaaacgtt gagtcaatca cgatggtgga aatcgatgcg ggtgtcgtat
    19201 cgttctgccg tcagtatcta cccaaccata acgccggtag ctacgacgat ccgcgcttta
    19261 agctggtgat cgacgatggc gtcaatttcg ttaatcaaac cagccagacc tttgatgtca
    19321 ttatctccga ctgcaccgat cctatcggtc ccggcgaaag ccttttcact tcggcatttt
    19381 atgaaggctg caaacgttgc ctgaatcctg gcggtatctt cgtcgcacaa aacggcgtct
    19441 gctttttaca gcaggaagaa gccatcgaca gccatcgcaa actcagccat tacttcagcg
    19501 acgttggctt ttatcaggcg gcgatcccga cctattacgg cggtatcatg acttttgcat
    19561 gggcgacaga taacgacgcc ttacgccatc tctcaaccga aattattcag gcgcgttttc
    19621 tcgcctctgg cctgaaatgc cgttattaca atccggcaat ccatacggca gcttttgcct
    19681 tacctcagta tctgcaagac gcactggctt cacagccgtc ctaaggagaa gataagaaat
    19741 tgaaaaaact gaaactgcat ggctttaata atctgaccaa aagtctgagt ttttgtattt
    19801 acgatatctg ctacgccaaa actgccgaag agcgcgacgg ttatattgct tatatcgatg
    19861 aactctataa tgccaaccgt ctgaccgaaa tcctgtcaga aacctgttcc attatcgggg
    19921 ctaatattct taacatcgcc cgccaggatt acgaaccaca gggtgccagc gtcactattc
    19981 tggtgagtga agaaccggtt gacccgaaac tcatcgacaa aacagaacac cccggcccac
    20041 tgccagaaac ggtcgttgcc catcttgata aaagtcatat ttgcgtacat acctacccgg
    20101 aaagtcatcc tgaaggcggt ttatgtacct tccgcgccga tattgaagtc tctacctgcg
    20161 gcgtgatttc tccgctgaag gcgctgaatt acctgatcca ccagcttgag tccgatatcg
    20221 taaccattga ttatcgcgtg cgcggtttta cccgcgacat taacggtatg aagcacttta
    20281 tcgaccatga gattaattcg attcagaact ttatgtctga cgatatgaag gcgctgtatg
    20341 acatggtgga tgtgaacgtc tatcaggaaa atatcttcca taccaagatg ttgcttaaag
    20401 agttcgacct taagcactac atgttccaca ccaaaccgga agacttaacc gacagcgagc
    20461 gccaggaaat taccgctgcg ctgtggaaag aaatgcgcga gatttattac gggcgcaata
    20521 tgccagctgt ttaacggctc tggcggagct cccaggctcc gccagattta tttacttctg
    20581 ctgcacgaaa ttgcggtaag ccgccacgac ctgcagaaaa tcctcaacgc cgcatagcga
    20641 caggctttct tcgtcgtagt agttcatccc ctcttccatt tcatcgccag cgaattccag
    20701 ttgattggcg cgaaccatca cctcttcacc gtccatccac agggtgtatt catgccctgc
    20761 ccgttgccag gaccgttcgc tacctttcag tgcgtgcgct gcttgttcca cttcatcaag
    20821 caaggccagg ttttctttca cctcttcatt aaaccagtgc ccgaccactt catgccccat
    20881 ggacatacgc acctttacca ctccggtaat atcgcgcaga aattcgtaat ccatagtgtg
    20941 ttcctctgct cccggcaatg caccgaaatc gcattgcgcc attgatgtaa ttatcgcagc
    21001 cttaccggag aaaaacagcg gaacggcgat ggtttagaaa taaaaaaatg cccgggaatc
    21061 tcattcaccg ggcattgtgt cgtttatgcg cagcgcgtgc gctgactttt taaaccgcag
    21121 tctggaaaat caccccatcg gctttctcgg tgtactgaga aagctggttg aagttcagat
    21181 aacggtaagt atcaacggct gttttatcta cctgcgccac gtaggtctgg tactcttccg
    21241 gcgtcggcag tttgccaatc agcgccgcaa cagccgccag ttccgcagaa gccaggaaga
    21301 cattcgcgcc agtacccaga cggttcggga agttacgggt agaggtggaa accaccgttg
    21361 caccgtccgc cacacgcgcc tggttaccca tacacaggga acagccaggg atctcgatac
    21421 gcgcaccact cttaccgaag acgctgtagt agccttcttc ggtcaactgt gcggcgtcca
    21481 tacgggttgg cggtgccacc cacaggcggg tcggcaactg acctttatgc gcatccagca
    21541 gtttacccgc agcacggaag tgaccgatgt tggtcatgca ggaaccgata aacacttcgt
    21601 cgatcttctc accctgtacc gcagacagcg gacgcgcgtc atccgggtcg ttcggagcac
    21661 acaggattgg ctctttaata tccgccagat cgatgtcgat cactgccgcg tattccgcat
    21721 ctgcatcggc ttccagcagc tcaggattcg ccagccattt ttccatgccc tgaatacgac
    21781 gttccagggt acgacgatcg ccgtaacctt ccgcgatcat ccacttcagc aggacgatgt
    21841 tagagttcag gtattcgatg atcggttctt tgttcagctt gatggtacaa ccagcggcag
    21901 aacgctcggc ggacgcatcg gttagctcaa aggcctgctc aactttcaga tccggcagac
    21961 cttcaatttc caggatgcgg ccagagaaga tgtttttctt gcctttcttc tcaacggtca
    22021 gcagaccttg tttgatcgca tacagcggaa tagcgtgtac cagatcgcgc agggtgatgc
    22081 ccggctgcat tttgcctttg aagcgcacca gaacggattc cggcatatca agcggcatta
    22141 cgccagttgc ggcagcaaac gccaccagac cagaacccgc cgggaaagag ataccgatcg
    22201 ggaaacgggt atgggagtca ccaccggtac cgacggtatc cggcagcagc atacggttca
    22261 gccaggagtg aatgacgccg tcacccggac gcagcgacac accgccacgg ttcataatga
    22321 agtccggcag cgtgtggtgc gtgttcacgt caactggctt cggatacgcc gcggtgtggc
    22381 agaaagactg catcaccagg tcagccgaga agcccaggca cgccaggtct ttcagttcat
    22441 cacgggtcat cgggccggtg gtgtcctggg aacctacaga agtcattttc ggttcacagt
    22501 acgcgcccgg acgaatgcct ttcacgccac aggcacggcc taccattttt tgcgccagcg
    22561 agaagccgcg atcgctctca gcgacatctt tcgcctgacg gaacacatca ctgtgcggca
    22621 gaccaagtgc ttcacgcgct ttggtggtca ggccacgccc gataatcagc ggaatacggc
    22681 caccagcacg cacttcatca atcagcacgt cggttttcag ttcgaaggtc gccagcagtt
    22741 cgccggtttc gtggttacgc acttcacctt tgtacgggta aacgtcaatc acgtcgccca
    22801 tgttcaggtt agagacgtcg acttcgattg gcagtgcacc cgcgtcttcc atcgtgttaa
    22861 agaagatggg tgcaatttta ccgccgaggc acaaaccacc gccgcgtttg ttcggcacat
    22921 gtggaatatc atcgcccata aaccacagaa cggagttagt ggcggattta cgcgaagaac
    22981 ccgtacccac aacgtcaccg acgtacgcca gcgggaaacc tttctgttgc agagcttcga
    23041 tttgcttgat cggaccaaca acaccaggct ggtctggctc aataccttca cgggcgtttt
    23101 tcagcatcgc cagcgcgtgc agtgggatat ccgggcgtga ccacgcatcc ggtgccggag
    23161 aaaggtcatc ggtgttagtt tcgccagtga ctttgaagac agtaacggtc agtttttcag
    23221 ccagcgccgg gcgattcagg aaccattcgg catccgccca ggactgcata acctgcttcg
    23281 catattcgtt gcctgctttc gctttctctt ctacgtcata gaagttatcg aacatcagca
    23341 gcgtgtgaga aagtgctttg gcagcaatag gtgccagttt ggcatcatcc agcgcgtcga
    23401 tcagcggatg aatgttgtaa ccaccctgca tggtgcccag cagttcgatg gctttttccg
    23461 gagtcagcag aggggatttg gcttcgcctt tcgcgatagc agccaggaag cctgctttga
    23521 cataggcggc ttcatcgacg cctgggggaa cacggttggt taacagatct aacaggaatt
    23581 cttcttcgcc cgcgggcggg tttttcagca gctctacaag tgcggccatt tggtttgcat
    23641 ccaggggttt gggcgcaatc ccctcagcgg cacgctcagc tacgtgctta cggtattctt
    23701 ctagcacgac ggttctcctc gctctcattg tcatagtgcg gcaggcgatt ctcttcacgc
    23761 tcctgtgaga cagcagtttg tagggtaaat gcccagtacc gcaacgggca gaatagcagg
    23821 attttgacga ggtgttaatc tgtttacaaa aaagcaacat aaaaaagtgg ctgaatcgtt
    23881 aaggatggtc tagagattgt ttccctccgt aaaaacttcg ttaattcgca tggtgataat
    23941 cacctttctc aacgaatccc aagattagtc aaaatttaaa ctaccgcctc tttatactcg
    24001 gattcacagc acctgcgggt ggcagttcgc cgaccattgc gatttccttg agatccgaat
    24061 tatgaaaatg actttgccgt ttaaacccca tgtgctggcg ctaatttgca gtgccgggct
    24121 ttgtgccgcc tctaccgggc tatatataaa aagccgcaca gtggaagcgc ctgtggaacc
    24181 gcaatcgaca caactggctg tgtctgacgc tgccgcggtt acgtttcctg caacggtttc
    24241 cgcacctccc gtaacacccg ccgtcgtcaa atccgcattc agcactgcac aaatagatca
    24301 atgggtcgcg cccgtcgcgc tgtatcccga cgccctactt tcgcaggtgc tgatggcatc
    24361 aacctatccg acaaacgttg ctcaagcagt gcaatggtcg cacgataatc cacttaaaca
    24421 aggcgatgct gctattcagg cggtatctga ccagccgtgg gacgccagcg ttaaatcact
    24481 ggtggccttt ccacaattga tggcattgat gggcgaaaac ccgcaatggg tgcaaaacct
    24541 gggcgatgct tttctggccc agccgcagga cgtgatggac tcggtacagc gattgcggca
    24601 actggcgcaa caaaccggct cgctgaagtc atcaaccgaa cagaaagtta ttaccacaac
    24661 gaagaaagct gtaccggtaa aacagacagt cacggcaccc gtcataccat ccaatacagt
    24721 tttaactgcc aaccccgtca ttacagagcc ggcaacaacc gtcatttcca ttgagcccgc
    24781 caatcctgat gtggtctata ttcccaacta caacccaacc gtggtttacg ggaactgggc
    24841 caatactgcg tatccgccgg tttatctgcc accaccagcc ggagaaccgt ttgttgacag
    24901 ctttgtacgc ggattcggct atagcatggg cgttgctacc acgtacgcac tattcagcag
    24961 catcgactgg gacgacgacg atcatgacca tcatcatcat gacaatgatg attatcatca
    25021 ccacgatggc ggtcatcgtg acggtaatgg ctggcaacac aacggcgaca acatcaatat
    25081 cgacgtcaac aatttcaacc gtatcaccgg tgagcatctt actgataaga atatggcatg
    25141 gcggcacaat ccaaactacc gtaatggtgt gccctatcat gatcaggata tggcaaagcg
    25201 gtttcatcaa accgatgtca acggcggaat gagcgccacg caattacctg ccccaacgcg
    25261 cgacagccag cgtcaggcgg cagcaaatca gtttcagcaa cgaacacacg ccgcaccagt
    25321 cattacacga gatacccaac gtcaggcagc ggcacagcgg tttaatgaag ctgaacacta
    25381 tgggagctat gacgacttcc acgacttcag ccgtcgccaa ctactgaccc agcaacaaaa
    25441 ggacgccgct cgtcagcgtt atcagtccgc ctcgcctgag cagcgccagg cagttcgcga
    25501 gagaatgcag actaacccga agatccagca gcgaagagag gcagcgcgtg agcgcattca
    25561 gtccgcctcg cctgagcagc gccaggcggt tcgcgagaaa atgcagacta acccgcagaa
    25621 ccagcagcga agagacgcag cgcgtgagcg tattcagtcc gcatcaccag agcagcgcca
    25681 ggtgtttaag gaaaaagtac agcagcgccc actgaatcaa cagcaacgtg ataacgcccg
    25741 ccagcgtgtt caatcggcat cacctgaaca acgtcaggtt tttcgggaga aagttcagga
    25801 gagccgccca caacgtctaa acgacagtaa ccatactgtc aggctgaata acgagcaacg
    25861 gtcagcagta tgcgaacgtc tctctgaacg tggagcaaga agactggaaa ggtaaattgc
    25921 agacgtaaaa aaagcggcgt ggttagccgc ttttttaatt gccggatgtt ccggcaaacg
    25981 aaaaattact tcttcttcgc tttcgggttc ggcaggtcgg taatgctacc ttcgaacact
    26041 tctgccgcca ggcccacaga ctcgtgcaga gtcgggtgcg cgtggatggt cagtgcgatg
    26101 tcttcagcat cacaacccat ttcgattgcc aggccgattt cacccagcag ctcgccgccg
    26161 ttagtaccga caatcgcacc accgatcaca cggtgagatt ctttgtcgaa aatcagcttg
    26221 gtcataccgt ctgcgcagtc ggaagcgata gcacgaccag aagcagccca cgggaaggtg
    26281 gcggtttcat agctgatgcc tttctctttc gcttctttct cagtcagacc cacccatgca
    26341 acttctggtt cggtataggc gatggacggg ataactttcg gatcgaagta gtgtttctta
    26401 ccggcgataa cttcagcggc aacgtgacct tcgtgaacac ctttgtgtgc cagcatcggt
    26461 tgaccgacga tatcgccgat agcaaagatg tgcggtacgt tggtacgcag ctgtttgtca
    26521 acgcggatga aaccacggtc gtcaacttcc acgcctgctt tgcctgcgtc gaggttttta
    26581 ccgttcggca cacgaccaat cgctaccagc acggcgtcgt aacgctgcgg ttcagcgggt
    26641 gcttttttgc cttccatcgt cacataaatg ccgtcttctt tcgcttcaac ggcggtaact
    26701 ttggtttcca gcatcaggtt gaatttcttg ctgatacgct tggtgaagac tttaacgatg
    26761 tctttgtcag ctgccgggat aacctggtcg aacatttcaa ccacgtcaat ctgtgaaccc
    26821 agcgcgtggt aaacggtgcc catttccaga ccgatgatac cgccacccat taccagcagg
    26881 cgttctggta cttctttcag ttccagcgcg tcagtggagt cccagatacg cggatcttca
    26941 tgcggaataa acggcagttg gatcgggcga gaacccgctg caatgatcgc gttgtcgaag
    27001 ttgatcacgg ttttgccgtt ctcaccttca acttccaggg tgttagcccc ggtgaattta
    27061 cccagaccgt tgaccacttt gactttgcgg cctttcgcca taccagccag accaccggtc
    27121 agctgattga tcactttctc tttccaggta cgaatcttgt cgatatcggt tttcggttcg
    27181 ccgaagacga taccgtgttc agccagcgct ttggcttctt cgataacttt tgctacgtgc
    27241 agcagtgctt tagaagggat acagccgacg ttcaggcaaa caccgccaag ggtgttgtaa
    27301 cgttctacga ttacggtttc cagacctaaa tcagcgcaac ggaaggcagc ggagtaacct
    27361 gcggggcctg ccccaagtac cacgacctga gttttgattt cagtactcat catgacctct
    27421 atatatttat ctccggcggt catacccgtc gtctttcagg ccgcagcggc gttagcttca
    27481 cgccctcacc ccagtcactt acttatgtaa gctcctgggg attctggcgc ttgctacctt
    27541 gctgcaccca gaaatccata gggtatgtga agtaataccc taaccaccac cgggtcgttc
    27601 tatccgtcgg tattttacaa aattgttaac aatttttaaa caacaaacgg caaccgattt
    27661 gtctattcgc taataacctc aatacattca tgagattacc agaaaaaagc cggccgttgg
    27721 gccggctctt ttacttacat caccagacgg cgaatgtcag acagcgtgtt gttaatgatg
    27781 gtaatgaaac gggcaccatc agcaccgtcg atcacgcggt ggtcgaagga gagagaaatc
    27841 ggcagcatca gacgcggcac gaactcttta ccattccaca ccggctccat cgcggacttg
    27901 gaaacgccga ggatagccac ttccggcgcg ttcacaatcg gcgcgaagtg ggtagtaccc
    27961 aggccgccga tgctggagat ggtgaagcaa ccgccctgca tttcgcccgc agtcagctta
    28021 ccgtcacgcg ctttcttaga aatagtcatc agctcgcgag acagctcgat gatgcctttc
    28081 ttgttgacgt ctttgaatac cggaacaacc agaccgttcg gggtatccac cgccacaccg
    28141 atgttgatgt atttcttcag ggtcagacgc tgaccgtctt ccgacagcga actattgaag
    28201 cgaggcatct gctcaagagc tgcagcaacg gctttcatga tgaagacaac cggggtgatc
    28261 ttcacatcca gcttacgttt cgccgcttct tcgttctgct gtttacggaa cgcttccaac
    28321 tcggtgatat cggttttgtc gaagtgagta acatgcggga tcattaccca gttacggctc
    28381 aggttcgcac cagagatttt ctggatgcgg cccagttcca cttcttcgat ttcaccaaac
    28441 ttgctgaagt ccaccttcgg ccacggcagc atgccaggga taccaccgcc agtcgctgcc
    28501 ggagctgctt ctgcacgttt gatagcttct ttcacgtaag cctgaacgtc ttcgcgcagg
    28561 atacgacctt tacggccagt gcccttcact ttcgcaaggt taacaccaaa ctcgcgtgcc
    28621 agacggcgga tcagcggagt cgcgtgaaca taagcgtcgt tttcagcaaa ttcagatttg
    28681 ccttccgctt tcgcagctgg tgctgctgcc ggggcttcag cttttgctgc cggtgccggc
    28741 gctgccgctt cctgtttcgc aggagctgcc gcaggcgctg cgccttcaac ttcgaagatc
    28801 ataatcagcg agccagtttt cactttatcg ccaacgttga ctttcagttc cttcacgacg
    28861 cctgcaaacg gcgccggaac ttccatagaa gctttgtcgc cttctacggt gatcagtgac
    28921 tgttcagcgg caactttgtc gcccactttc accatcactt cagtcacttc aacttcgtca
    28981 ccgccgatat ccggaacgtt aacttctttc acgccagccg ctggtgcagg ggccgctgcc
    29041 ggagctgctt cctgtttagc ggccggagct gccgcgcctg cttcacccgc gacttcgaag
    29101 accataatca gcgagccggt agacactttg tcacccacgt tcactttgat ctctttcacg
    29161 gtgccagcaa acggagccgg aacttccata gaagccttgt cgccttctac ggtgatcagc
    29221 gactgttcag cttcaacttt atcgccaact ttcaccagga tttcggtcac ttcaacttcg
    29281 tcgctgccga tatccggaac gttaacgtct tttgccgccg cagccgctgg tgctgctgcc
    29341 ggagctgctt ctttcttctc ttctgcctga gcaggtgcag cgtctgctgc accgtcggcg
    29401 gaatcgaaaa tcataatcag tgcgccggtc tgggttttat cgccaacaga gactttgatc
    29461 tctttaacga tacccgcctg cggagacgga acttccatag aggctttgtc gccttctacg
    29521 gtgatcagcg actgttcggc ttcaactttg tcgcccactt tgaccaggat ctcggtgatt
    29581 tcaacttcat cagccccgat gtccggtact ttgatttcga tagccattat tcttttacct
    29641 cttacgccag acgcgggtta actttatctg catcgatgtt gaatttggcg attgcgtcag
    29701 caaccacttt cttatcgatt tcgccacgtt tagccagttc gcccagcgcc gcaaccacga
    29761 cataagaagc atcaacttcg aagtggtgac gcaggttctc acggctgtcg gaacgaccga
    29821 agccatcagt acccagtacg cggtagtcgt cagccggtac gtaagtacgg acctgctcag
    29881 cgaacagttt catatagtcg gtagatgcca ctgccggagc gtcgttcatc acctgagcga
    29941 tatacggaac gcgcggagtt tccagcgggt gcagcatgtt ccagcgttca caatcctgac
    30001 catcacgcgc cagctcggtg aaggaggtca cgctataaac gtcagaacct acgccgtaat
    30061 ctttcgccag gatctcagct gcttcacgga cgtgacgcag gatagaaccg gagccgagca
    30121 gctgaacttt acctttgcta ccttcaatag tttcgagttt gtagatacct ttacggatac
    30181 cttcctcagc accttccggc attgccggca tgtggtagtt ttcgttcagc gtagtgatgt
    30241 agtagtaaac gttctcttgt ttttcaccgt acatacgctc cagaccgtca tgcatgatga
    30301 cagcaacttc gtaagcgtaa gccgggtcgt aagagataca gttcgggata gtcagcgact
    30361 gaatgtggct gtgaccatct tcgtgctgca gaccttcgcc gttcagggtg gtacgaccgg
    30421 aagtaccgcc gatcaggaag ccacgcgctt gctggtcgcc agccgcccag cacagatcgc
    30481 caatacgctg gaagccgaac atcgagtaat agatgtagaa cgggatcatc ggcagattgt
    30541 tggtgctgta agaggtcgcc gctgccagcc aggaacaacc tgcgcccagc tcgttgatcc
    30601 cttcctgcag aatctgacct ttctcgtctt ctttatagta agcaacctgc tcgcggtcct
    30661 gcggggtgta ctgctgaccg ttcgggctgt aaataccaat ctgacggaac agaccttcca
    30721 taccgaaagt acgcgcttcg tcggcgatga tcggtaccag acgatctttg atcgacttgt
    30781 tcttcagcat cacgttcaga gcacgaacga aagcgatagt ggtagagatc tctttgctct
    30841 gctcttccaa cagcgcgccg aagtcttgca ggctcggcag ctcaagcttc tcggtgaagt
    30901 tcggctgacg gcttggcaga taaccgtgca gtttctgacg ctgagcgtgc agataggtat
    30961 gctcttcaga accttccggg aaggtgatgt acggcagttt ttcgatatct gcatcagaca
    31021 ccggcacatt gaaacggtcg cggatatgac gcacaccgtc catgttcatt ttcttaacct
    31081 ggtgcgcgat gtttttacct tcagccgcgt cgcccatgcc gtaaccttta atggtatgag
    31141 caaggattac tgtcgctttg cctttggttt cctgcgcttt cttgaatgca gcgtagattt
    31201 tcttcggatc gtgaccacca cggttcagtg cccagatctg ctcgtcagtc cagtctgcaa
    31261 ccagtgctgc ggtttcagga tatttaccga agaagtgttc acgaacgtac gcaccatctt
    31321 tcgatttgaa ggtctggtag tcgccgtcaa cggtttcgtt catcagctgg atcagtttac
    31381 cgctggtatc cttacgcagc agttcatccc aacggctacc ccacatcact ttgatcacgt
    31441 tccagccagc accttcgaag atgccttcca gttcgttgat gatcttgccg ttaccggtga
    31501 ccgggccgtc aagacgctgc aggttacagt tgataacgaa gaccaggtta tccagttttt
    31561 cacgggtagc gatggtgatc gcacctttgg attccggttc gtccatttca ccgtcaccga
    31621 ggaacgcgta aacggtttgt ttagaggtat ctttcaggcc acggtgttcc agatatttca
    31681 ggaatttagc ctggtaaata gcaccaatcg gacccagacc catagatacg gtcgggaact
    31741 gccagaattc cggcatcagt ttcgggtgcg gataggaaga gaggccattg ccgtgaactt
    31801 cctgacggaa gttatccagc tgctcctgag tcagacgacc ttccaggaaa gcacgagcgt
    31861 acacgcccgg ggagatgtgg ccctggaagt aaaccaggtc gccgccatcc tgctcgttgc
    31921 gtgcacggaa gaagtggtta aagcacacat cataaatggt tgcggaagac tggaaggacg
    31981 ccatatggcc gcccagttcg aggtcttttt tcgacgcacg cagcaccgtc atgatggcgt
    32041 tccagcggat agctgaacga atacggcgtt ccagttccag attacccgga tactccggtt
    32101 gttcttcaac ggggatggtg ttgatgtagt tgctgatacc tgtgcctgcg gctacgttta
    32161 caccgccttt gcgggcttca gcaagcagtt ggtcgatcag atactgagca cgctcaacac
    32221 cttcttcacg gatgaccgat tcgatcgcct ggagccagtc gcgagtttcg atcggatcca
    32281 cgtcatttgg gaaacgttct gacatgggtt attccttatc tatctaataa cgttgagttt
    32341 tctggaacct gtcccattga actctcgccg gaaagctcaa taagacaggt tctacgttta
    32401 gttgccgcgc ttttatatgc gcttgattta caacatcttc tggataattt ttaccagaaa
    32461 aatcactaat tctttcgttg ctccagacga cgcagagaac gctcacggcg gctctcttca
    32521 cgacttctgt cgagcaaaat ttcttcgata aaggccagat ggcgatgcga tgcttcgcgc
    32581 gcttcttccg gcttaccggc cataatcgct tcaaatatgc gggtgcggtg actactcacc
    32641 agcggcagca tctcgcgacg cgaatagagc aattcgaagt tctggcggac attctgggcc
    32701 aacatcggct ccatacacct tagcagatga agcagaacca cattgtgggc cgcttcggtg
    32761 acggcaatct gatactggag tacggcgttt gattccgcgt ccagatcgcc agactgctgc
    32821 gccagctcta tggcgtggtg gagttcacgg atgcgttcct tgtcttcatc ggtactacgc
    32881 agcgcggcgt aataagcggc gataccttcc agggcgtgtc gtgtttcgag caagtcatac
    32941 tgtgactcag gatggtcgga gagcagctcc accagcggat cgctgaagct ttgccatagg
    33001 ctgctctgga caaaagtgcc gccaccctgg cgacgaagca acaagccctt cgcttcgaga
    33061 cgttgaatcg cctcacgcaa ggagggacgg gagacgtcaa actgttttgc cagttcgcgt
    33121 tccggtggga gtttttcgcc cgggcggaga gtgccttcga ggatcaaaaa ctccagttgc
    33181 tgctcaatca catcggagag ttttggttgg cggattttgc tgtaggccat gagttcctgt
    33241 cttaagccac ttgccgaagt caattggtct taccaatttc atgtctgtga cgctaaagta
    33301 acaaagtatt caccttatgt ccatacaggt tttgattgaa atcatgaaac tgtgcacatt
    33361 ttaacaactt gacatatata acgtttcaaa gttgtaacta tgcacaaatg tagactttac
    33421 gtaggaaagg agttttttaa cgattattaa actataaaaa tccgaattga accgattcac
    33481 ttaccaattt tgtgattttt aattcaatta aaacgaattt aaattcattc tacatattga
    33541 gaggggttga ggctgagctt tacaaacggt ttctttttaa gcaactcatc ttcaaccatg
    33601 cataaagcgg gtgcattcgc tgccgcatac cattattctt gatctgacgg aagtcttttt
    33661 gtaacaattc aaacttcttt gatgtaaaca aattaataca acaaacggaa ttgcaaactt
    33721 acacacgcat cactgcgtag atcaaaaaaa caaccaccgc acgaggtttc atgatggaag
    33781 gtcaacagca cggcgagcag ctaaagcgcg gccttaaaaa ccgccatatt cagcttatcg
    33841 cgctgggtgg cgcgataggg accgggttat tcctgggtag cgcctccgta atacagtccg
    33901 cagggccagg gattatcctg ggttacgcca ttgctggttt tatcgccttt ctgatcatgc
    33961 gtcagctggg tgaaatggtg gtcgaagaac ctgtcgcagg ctcctttagc cactttgctt
    34021 ataaatactg gggcagtttt gccggtttcg cctctggctg gaactactgg gtactgtacg
    34081 ttttagttgc catggctgag ctgactgccg tgggtaaata cattcagttc tggtatccgg
    34141 aaatccccac ctgggtttct gccgccgtat tctttgtggt gattaacgcc atcaacctga
    34201 ccaacgttaa agtgtttggc gagatggagt tctggtttgc cattatcaaa gttatcgcgg
    34261 tggtagcgat gatcatcttc ggcggctggc tgctattcag tggcaacggc ggcccgcagg
    34321 cgaccgttag caacctgtgg gatcagggtg gtttcctgcc gcacggcttc accgggctgg
    34381 tgatgatgat ggcgattatc atgttctcgt tcggtggtct ggaactggtg gggatcaccg
    34441 cagcagaagc tgataacccg gagcaaagta taccgaaagc aactaaccag gttatctacc
    34501 gcatcctgat tttctatatt ggttcgttag ccgttctgct ctcactgatg ccgtggaccc
    34561 gcgttaccgc cgataccagt ccgtttgtgc tgatcttcca cgagttaggc gatacctttg
    34621 tggcgaatgc gctgaacatc gtggtactga ctgcggcgct ctccgtgtac aacagctgcg
    34681 tatattgcaa cagccgtatg ctgtttggtc tggcacaaca gggtaatgcg ccaaaagcgc
    34741 tggcgtctgt cgataaacgt ggtgtaccag taaataccat tctggtgtct gcactggtaa
    34801 cggcgttgtg cgtactgatt aactaccttg ccccagagtc cgctttcgga ctgttaatgg
    34861 cgctggtggt atctgcactg gtaatcaact gggcgatgat tagcctggcg catatgaaat
    34921 tccgtcgcgc caagcaggaa caaggcgtgg taactcgctt ccctgctctg ctttatccgc
    34981 tgggtaactg gatctgcctg ctgtttatgg cggcggtact ggtgattatg ctgatgaccc
    35041 caggaatggc gatttcggta tacctgatcc cggtatggct gatcgtgtta ggtatcggct
    35101 atctgtttaa agagaaaacc gccaaagccg taaaagcgca ttaatctctc tacgccctca
    35161 cccgtacagg gtgagggcaa taatctttac accaacgccc cgtaaatcgt cagtagtgca
    35221 atcaccacca cgaccacgaa cgaggttttc ttcgccattg aaaccgctgc cttcggcgtc
    35281 tccaccttat cgacatgcgg ttcacgcgcc agagagaact gcgccagacg cgttaacacc
    35341 tgatactgcg aagtatggaa atcacccagc gaagcaaacc aggccggtaa cgctttctca
    35401 ccatgaccga tcaaggcata taccacaccc gcaagacgaa ccggcaccca atccagtaca
    35461 tgaagcacgg catcaatgcc ggactgtaaa cgatgatgcg gcgtctgata tcgcgccagc
    35521 cagtattgcc atgcacgcaa aaacgcatac cccatcagcg taacgggtcc ccaggttccc
    35581 cccacaatca gccagaacag cggtgcaaga taaaaacgaa agttaatcca cagcaatgca
    35641 ttttgcagct cacgcaaata ctcacgttcg tcgcagcctg ccgggacgcc gtgaatcatg
    35701 gtgagttcgc cagccatcgt ggcacgggca tggctatcat tacgtgaagc agctgtcaga
    35761 taagcatgat aatgaagacg aactttacct gcgccaatac acagcaaacc aatcagcagc
    35821 cacaccagta gcgtgggaac gttgaacaat actccctgca atgcgcgtaa cagtaaaaaa
    35881 gtcacgccca tcgcaataat ggtcatgcct aacgtgcgcc cgagagaaaa atgtttcacc
    35941 cgccgaaaga acgcttcaag acgatgatca agctgccagt gctcgcccaa cttaaacagg
    36001 cgctcgaaaa ttaacaccag taaggttgta aatagcgtca tgttgtctcc ttgctgacca
    36061 gcacacgaaa ccgtgcccaa tcaaatgcag gaccgggatc ggttttccga tccggcgcaa
    36121 tatcacaatg gcccgtcatg tttttagcga tatccggata gcaatcaatc agtgcccgcg
    36181 taaccgccgc aagctgttga tactgcgcat cggtatacgc cagcgtatcg gtgccttcaa
    36241 gctcaatccc aatagaaaaa tcattgcagc gttcgcgccc ctgatactga gagactcccg
    36301 catgccatgc acgtttatcg aaaggaacat actggactat ttcaccatca cggcgaatca
    36361 aacagtgagc ggagacgcgc aaatgggcga tctcagcaaa gaaaggatgt gcctgcggat
    36421 caatagttcc agtgaataat gcgtcgatcc acggaccgcc aaactcgcct ggcggcaggc
    36481 taatattgtg caccaccagc agggtgggtg tttcgtcatc cgggcggcaa tcgtaatgtg
    36541 gtgagggaac gcggcgcgcg ccaaccagcc acccctgttc taacaacatg caggatctcc
    36601 ttatatgtgg tgctaatacc cggttcagag tagcatgttt ctaccttatg attcgttagc
    36661 tatctggagt tttaacatgc cgcctcgccg ctataaccct gacacccgac gtgacgagct
    36721 gctggaacgc attaatctcg atatccccgg cgcggtggcc caggcgctgc gggaagattt
    36781 aggcggaaca gtcgatgcca acaatgatat tacggcaaaa cttttaccgg aaaattctcg
    36841 ctctcatgcc acggtgatca cccgcgagaa tggcgtcttt tgcggcaaac gctgggttga
    36901 agaggtgttt attcaactgg caggcgacga tgtcaccata atctggcatg tggatgacgg
    36961 cgatgtcatc aatgccaatc aatccttgtt cgaacttgaa ggcccatccc gcgtgctgtt
    37021 aacgggcgaa cgcactgcgc ttaattttgt gcaaaccctt tcaggagttg ccagtaaggt
    37081 acgccactat gtcgaattgc tggaaggcac caacacgcag ttgttggata cgcgcaaaac
    37141 cttacccggc ctgcgttcag ctctgaaata cgcggtactt tgcggcggcg gagcgaatca
    37201 ccgtctgggg ctttctgatg ccttcctgat caaagaaaac catattattg cctccggctc
    37261 agtgcgccag gcggtcgaaa aagcgtcctg gctgcacccg gatgcgccag tagaagtcga
    37321 agtagagaat ctggaagaac ttgatgaagc cctgaaagca ggagccgata tcatcatgct
    37381 ggataacttc gaaacagaac agatgcgcga agccgtcaaa cgcaccaacg gcaaggcgct
    37441 actggaagtg tctggcaacg tcactgacaa aacactgcgt gaatttgccg aaacgggcgt
    37501 ggactttatc tccgtcggtg cgctaactaa acacgtacaa gcactcgacc tttcaatgcg
    37561 ttttcgctaa tagttgacag atttatccgc tccatcgcgg gcggataatc tccccttccc
    37621 caactttctt cgtaacgcct cgcaaatttc ttgtctttcg ctgcaacgaa ataaaaaacc
    37681 tcggaatctg ctttcccgtt tcgttttttg cccctcgcct gtgctgatgg cgtttgccaa
    37741 agtagcgcca accaaatcaa ggagcgaaac agatggacaa gcaacgcggt tttacactta
    37801 tcgaactgat ggtggttatt ggcatcattg ccattttaag cgccattggt attcccgctt
    37861 atcaaaacta cctgcgcaaa gccgcactca ccgacatgct acaaaccttt gtgccttacc
    37921 gtaccgccgt agagttgtgc gcgctggaac atggtggatt agatacctgc gacggtggca
    37981 gcaatggcat tccctcgcct accaccaccc gctatgtttc agccatgagt gtggcaaagg
    38041 gcgtggtgtc gctgaccggg caagaaagtc tcaatgggct aagcgtcgtc atgacaccgg
    38101 gttgggataa cgcaaacggc gtcaccggct ggacgcgcaa ctgcaatatt caaagtgaca
    38161 gcgcattgca gcaagcctgc gaagatgtct tccgctttga tgacgccaac taaggagcgg
    38221 caatgaatat tccacagctc actgccctgt gtctgcgtta tcatggagtc ttgctggatg
    38281 ccagcgaaga ggtggttcat gttgcggtag tcgatgcacc ttcgcatgag ctactggacg
    38341 cattgcattt cgctaccacc aaacgtattg agatcacctg ctggacgcgc caacaaatgg
    38401 aaggtcacgc cagtcgcaca caacagacat tgcccgtagc tgttcaggag aagcatcagc
    38461 ccaaagcaga gttgctaact cgaacgttac aatctgcgct ggaacaacgc gcgtctgata
    38521 ttcatatcga accagcggac aatgcctacc gcatccgctt gcgtatcgac ggcgtattgc
    38581 atcctttacc ggatgtttca ccggatgccg gagtcgcatt aaccgccaga ttaaaagtgc
    38641 tgggaaacct ggatattgcg gaacatcgcc tgccgcagga cgggcaattc actgtcgaac
    38701 tggcaggaaa cgccgtctca tttcgtattg cgaccttacc atgtcggggt ggtgaaaagg
    38761 tggtattaag gttgttacag caggtgggtc aggcactgga tgtcaacacg cttggaatgc
    38821 agccgttaca actggcggac tttgctcatg ccttgcaaca accacaggga ctggtgctgg
    38881 taactggccc taccggcagc ggcaaaacgg tcacgcttta tagtgccctg caaaagctga
    38941 ataccgctga cattaatatt tgtagcgtcg aagatccagt tgagatcccc atagccggac
    39001 taaaccagac gcaaatccat ccgcgtgccg gactcacctt tcagggcgtt ttgcgtgcgt
    39061 tattgcgcca ggatcctgac gtcatcatga tcggagagat ccgcgatggc gaaacagcag
    39121 agatcgctat taaagcggcg caaactggtc acctggtgtt gtctacccta cacactaatt
    39181 ccacctgcga aacgctggta cgtttacagc aaatgggggt cgcccgctgg atgctatcat
    39241 cggcgcttac gctggtaata gcccagcgtc tggtacgcaa actttgccca cattgtcgcc
    39301 ggcagcaagg ggagcccatc cacattccag acaatgtatg gccatcgccg ctgccccact
    39361 ggcaggcacc cggttgtgta cattgctacc acggttttta tggtcgtacg gccttatttg
    39421 aagttctgcc cataacgccg gtcattcgtc agcttatttc cgctaatacc gacgttgaat
    39481 cgctggaaac gcacgcacga caggcgggta tgcgtacgct ttttgaaaac ggctgcctgg
    39541 ccgtagagca aggcttaacc acctttgaag agttaatccg cgtactgggg atgccgcatg
    39601 gcgagtaagc aactctggcg ctggcatggc ataaccggcg acggcaatgc gcaagatggg
    39661 atgctatggg cagagagccg tactttactg cttatggcac tacagcaaca gatggttacc
    39721 ccactaagcc tgaagcgaat cgccatcaat tctgcgcagt ggcgaggaga taaaagcgcg
    39781 gaagtcattc atcaactggc gacgctactc aaagcagggt taacgctttc tgaagggctg
    39841 gctctgctgg cggaacagca tcccagtaag caatggcaag cgttgctgca atcgctggcg
    39901 cacgatctcg aacagggcat tgctttttcc aatgccttat taccctggtc agaggtattt
    39961 ccgccgctct atcaggcgat gatccgcacg ggtgaactga ccggtaagct ggatgaatgc
    40021 tgctttgaac tggcgcgtca gcaaaaagcc cagcgtcagt tgaccgacaa agtgaaatca
    40081 gcgttacgtt atcccatcat cattttagcg atggcaatca tggtggttgt ggcaatgctg
    40141 cattttgttc tgccggagtt tgccgctatc tataagacct tcaacacccc actaccggca
    40201 ctaacgcagg ggatcatgac gctggcagac tttagtggcg aatggagctg gctgctggtg
    40261 ttgttcggct ttctgctggc gatagccaat aagttgctga tgcgccgacc gacctggctt
    40321 atagtgcggc agaaattgct gttacgcatc ccgattatgg gttcactgat gcggggacaa
    40381 aaactcacgc agatctttac gattctggcg ctgacacaaa gtgcaggcat tactttttta
    40441 cagggcgtag agagcgtcag agaaacaatg cgctgcccgt actgggtgca acttctgaca
    40501 caaatccagc acgatatcag taacggtcaa cccatctggc tggcgctaaa aaataccggt
    40561 gagtttagcc cgctctgttt gcaattagtg agaacaggag aggcatccgg ctctctggat
    40621 ctcatgttag acaacctcgc ccatcatcat cgggaaaaca caatggcgct ggcggataac
    40681 ctcgcagcct tactggaacc ggcgttgctg atcataacgg gaggaattat tggtacgctg
    40741 gtggtggcaa tgtatctgcc aattttccat ttaggcgatg cgatgagtgg gatgggataa
    40801 cgctggcgtg ttgctccacg ccagcgttgg gagattacag gttgttgaag atgcggtttt
    40861 cttgttcctg cacacgaata aacgtggtgc gcttggtcag ctctttcagg cgtgaagccc
    40921 caacgtatgt acaagctgaa cgcaggccgc ccaaaatatc tcgcgcggta ttttcaaccg
    40981 ggcctcgcag cggcagctta acggttttac cttctgctgc gcgatattcc gcaacgccgc
    41041 caacgtgacg tttcatcgca gactcggagc tcatgccgta gaacagcata aatttctcgc
    41101 cgttctcctc aacgatgcga ccgccgctct cttcgtggcc cgccagcatg ccgccaagca
    41161 tgacgaaatc ggcaccgccg ccaaaggctt tcgccacatc gcccggcgtg gtgcagccac
    41221 catcgctgac gatcattccg cccagaccgt gcgcagcatc ggcacattcg attaccgcag
    41281 aaagttgcgg ataaccgacg cctgttttga cgcgagttgt acaaacagaa cctgggccaa
    41341 tgccaacttt aacgatatcg gcacctgaga ggataagctc ctcacacatt tcaccagtca
    41401 ctacgttacc agcacaaatg gttttggtcg gccacgcttc acgcgctttc gcaacgaact
    41461 gcacgaagtg ttcggaataa ccattcgcca cgtcaataca aacgaagttt aatgccgggt
    41521 tcaggtcgag aatctgttta gttttttcga aatccgcatc agacgtaccg gtagaaacca
    41581 tcacatgttt cagcacatca gcggaagaat tgttgataaa cgcttgccac tcttcgacag
    41641 aatagtgttt atgcacagca gtcaaaatat caaaagaagc cagcgcagag gccatagaaa
    41701 atgtgcctac ggtgtccata tttgcggcga taatcggcac gccggaccag ctctgacctg
    41761 aatgtttgaa ggtgaattga cgttccagtt caacatcgga acggctttta agagtggagc
    41821 gtttagggcg gatgagaacg tctttaaaac ctaacttcag atcttcttca atacgcatgt
    41881 gcggattcct ggggttaatg gctataaggg taagagcgca actccagtga cgctatcata
    41941 cgcactaatc aatgcggcgc aagactgcga aattgtcttt ttttacgcta caatcccata
    42001 aatttacctg gtaaatagtg agcgaacgtt tcatcaattt cgctttcgtg cactcatttt
    42061 taacgttttg ataatcatga tgaattcccg ggaatataaa ttatgaggta tatagttgcc
    42121 ttaacgggag gcattggcag tggcaagagt accgttgcca atgcgtttgc tgatctcgga
    42181 attaacgtca ttgatgccga tattattgcg cgtcaggtgg ttgaaccagg tgcacctgcg
    42241 ctacatgcca ttgctgatca ctttggcgct aacatgattg ctgctgatgg aacattgcag
    42301 cgccgggcct tgcgcgagcg gatcttcgcc aacccggaag agaaaaactg gcttaacgcc
    42361 ctgctgcatc cgctgattca gcaagagacg caacaccaga tccagcaagc tacttccccc
    42421 tatgtactgt gggttgtgcc attgctggta gaaaactcac tgtataaaaa agcgaatcga
    42481 gtgcttgtgg tggatgtcag cccagaaacg caacttaagc gcaccatgca gcgcgatgat
    42541 gtaactcgcg agcatgtcga acaaatcctt gctgctcagg caacgcgcga agcccgcctt
    42601 gccgtggcag atgacgtcat tgataataac ggcgcaccgg atgctatcgc atcggatgtt
    42661 gcccgcctgc acgcacacta tttgcagctt gcgtcgcagt ttgtctcaca ggaaaaaccg
    42721 taatgcagac ccaggtcctt tttgaacatc cactaaatga aaaaatgcgt acatggctgc
    42781 gcattgagtt tttgattcag caactcaccg ttaatttacc catcgttgac cacgctggcg
    42841 cgctgcattt cttccgtaat gtcagtgaat tactggatgt tttcgagcgc ggcgaagtcc
    42901 gcactgagct gttgaaagaa cttgaccggc agcaacgtaa actccagacc tggattggcg
    42961 tgcctggcgt ggaccagagc cgtattgaag cattaattca gcagttaaaa gcggcgggga
    43021 gcgtattaat ttccgcgccg cgtatcgggc aatttctgcg tgaagatcgt ttgattgctc
    43081 tggtgcgtca gcgactgagc atcccaggcg gctgttgcag ctttgattta cctacattgc
    43141 acatttggct gcatctaccc caggcgcagc gcgacagcca ggtagaaacc tggattgcca
    43201 gcctgaaccc gctcacccag gcacttacca tggtgctgga tttaattcgc cagtcggccc
    43261 ccttccgtaa acaaaccagc ctgaatggtt tttatcagga taacggtggc gatgccgact
    43321 tgctgcgcct gaatctgtcg ctcgattcac agctttatcc gcaaatttcc ggacataaga
    43381 gccgttttgc cattcgtttt atgccgctgg acactgaaaa cggacaggta ccggaacgtc
    43441 tggatttcga actggcctgt tgctaaggag taaaaatgtc agaaactatt acggtgaatt
    43501 gcccaacctg cgggaaaacg gtggtgtggg gtgaaatcag cccgtttcgg ccattttgct
    43561 ccaaacgttg tcagctgatc gacctcggag aatgggctgc tgaagaaaaa cgaatcccca
    43621 gcagtggcga tctttccgaa agcgatgact ggagcgaaga accaaagcag tgacatttgt
    43681 ctgatgccgc acgtaggcct gataagacgc ggacagcgtc gcatcaggca tcttgtgcaa
    43741 atgtcggatg cggcgtgaac gccttatccg acctacaaaa acaaatttat caatgagtta
    43801 gaaatccctt taggcctgat aagacgcgcc agcgtcgcat caggcatcgt gtgcgaatgt
    43861 cggatgcggc gaaaacgcct tatctgacct acagacgttt aagcttcgca attaccggtt
    43921 cattggctgg cggaaaatca tcggcattaa gaccgaccag cgacatccac tcaccgggtt
    43981 gcccttcttt accccacggc tccccttccc agcgttcgac cagccaaaac cacagtgtta
    44041 tatgcctgtc cgggaattca tattccagtt tttcaaatag cgaaaaatgt tggggggtaa
    44101 tcccgacttc ttcctgaagt tcacgcacca ccgcctgttc cggcgtttca cccatttcaa
    44161 ttttaccgcc gggaaactcc agtttattcg ccatgtgcgc atctgctgcg cgacgcgtta
    44221 taaagatttc attgttctcg ttgcgaataa tacctaccgc aatttgcagc tttttcattg
    44281 tcttaaacct ataaaaaagg cgcagaatcc tgcgcctttt acttcaacag ttagctttta
    44341 ttgcaggcgg ccatggcact gcttgtattt tttaccagaa ccgcacgggc aaggatcgtt
    44401 acgtcctact ttgcgctctc cggtttgcgc cgccagtgca gctgcggctg cagagtcgtc
    44461 atcctgatgg ctaagctgct gcatttgcgc taaacgctcg gcttccatac gacgctgttg
    44521 ttccagctcc tcaacctctt caggcatacg tacctgaact ttgctcagcg tactgataac
    44581 ttcatatttc aacgactcca gcatcgctgc aaacatggag aacgattcac gtttgtattc
    44641 ctgcttcgga tctttctgtg cgtagccacg caggtggata ccctgacgca gatagtccat
    44701 cgctgccagg tgctctttcc acagggagtc aagcgtttgc agcatgacgc ctttctcgaa
    44761 gtgacgcatc atctcagcac caaccacttc ttctttacgc tgatacactt cgatggactg
    44821 cgccagaatg cgctcacgca gcgtctcttc atgcagttct ggttctttat ccagccactc
    44881 ggcaattggc aaatcgaggt cgaaatcgtt cttcagacgt tcctgcagcc ccggaatatc
    44941 ccacatttct tccagcgact gtggtggaat gtaggcatca atggtcgctt tgaacacatc
    45001 ttcacgaatg ctgttaatgg tttcgctcac atcgctgaca tccaacagtt cgttacgctg
    45061 ggagtaaatg gcgcgacgct gatcgttagc cacgtcatca tattccagca gttgcttacg
    45121 aatgtcgaag ttacggcttt caactttacg ctgggcgttg gcaatcgctt tagtcaccca
    45181 cgggtgttca atggcttcgc ctggcttcat acccagttta cgcatcatgc cggatactcg
    45241 gtcggaagca aaaatacgca tcagcgcatc ttccatcgac aggtagaaac gggaagaacc
    45301 agcatccccc tgacgaccag aacgaccgcg caactggtta tcgatacgac gggattcgtg
    45361 acgctcggta ccgatgatat gcaggccacc tgcttccagt accgcatcgt gacgtacctg
    45421 ccagtcggct ttaatttttt caatttgctc tgcggtcgga ttttccagcg cggcaacttc
    45481 tgcctgccag ctaccaccga gcacaatatc tgtaccacga cccgccatat tggtcgcgat
    45541 agtcaccgca gccggataac ctgcctgagc aacaatcgcc gcttcgttgg cgtggaattt
    45601 ggcgttcagg acgttgtgct taataccggc tttggtcagt tcgtttgaca ccagctccga
    45661 tttttcgatg gagatagtac ccaccagcac cggctggcct ttcgcagtac gttctttgat
    45721 atcttcaatg atcgcctgaa ttttttccgc ttcagtcatg tagaccaggt ccggcagatc
    45781 tttacgaatc attggacggt tggtcggaac aacgacggta tccagcttgt agattgagct
    45841 aaattcgaaa gcttcggtat cagcagtacc ggtcatcccc gccagttttt catacagacg
    45901 gaagtagttc tggaaggtga tcgaagccag cgtttggttt tcgttctgga tctgcacacc
    45961 ttctttcgct tccacagcct ggtgcagacc atcggaccag cgacggccct gcatggtacg
    46021 accggtgtgt tcgtcaacga tgataacttc accatcttta acgatgtagt cgacgtcacg
    46081 ggtaaacagc gcatgagcgc gcagcgccgc cgttacgtgg tgcatcagca tgatgttggc
    46141 cggagagtac agagactccc cttcatccat gatgccctct ttcaccagca gttcttcaat
    46201 cagcaccaga ccacgttcgg tcaggttcac ctggcgagat ttttcgtcca ccgagaagtg
    46261 gccttcgccc tggaaggttt cggagtcttc tttttcctga cggatcaggt gcggaataat
    46321 tttattcacg cgtttataca tttccgagct gtcttctgcc gggccggaaa tgatcagcgg
    46381 tgtacgcgct tcatcgatca ggatggagtc cacttcgtcc accagcgcat agtgcagttt
    46441 acgctgtaca cgttcttcag ggctgaacgc catgttgtcg cgcaggtagt caaagccgta
    46501 ttcgttgttc gtaccgtaag tgatgtcagc tgcgtaagct tcgcgctttg ccggtgctgg
    46561 catgcccggc aggttgatac cgacagtcag gccaaggaat tcaaacagcg gacggttgtt
    46621 ttcggcgtca cgttgcgcca ggtagtcgtt gacggtaact acgtgcacgc ctttaccggt
    46681 tagtgcgttc aggtaagcag gcagcgttgc ggtcagggtt tttccttcac cggtacgcat
    46741 ttcggcgatg cagcgttcgt taagaaccat accgccgagt aactgaacgt cgaagtgacg
    46801 cataccaaag acgcgcttac ttgcctcacg taccacggcg aaagcttccg ggatcagatt
    46861 ttccagcact tcgccttttt ccagacgtgc acgaaactct gcggttttcc ctttcagttc
    46921 ttcgtcggag agtttttcca tctccggttc catggcattg atgatgttga ccactttgcg
    46981 catccggcgc agggtgcgat cgttacgact accgaaaact ttagttaaca atttgattag
    47041 cataataaaa tctcaaacgc cccgcattgc ggagttaata aaatgaagta aaggtttatt
    47101 gttgttaggt gaggcgttga gggccagcac ggatgccttg cgcctggctt atccagacgg
    47161 gcgtgctgaa ttttgcttgt ggggtaaaat gcgcataatc aatgcgataa cccttttcag
    47221 acggcgtgcc ttcctgggtc agcagcgcgc tgagcgtatc cagtaatgca agatgttgcg
    47281 cctgaagagg caaagattct tcagcaacgg gcagtgtttg cggtgccatt gcgaaagaaa
    47341 gatgacggat taccgtgcga atggcatgtt gatgccagta atcaacggaa tagttcgaat
    47401 tcgggcggcg tgtgttcgct tccagcaagg ccaattgacc aaagttaact ttggctgaag
    47461 gctcgtggtt gcgggttgtc gcttttgcgg gcgcgtttgg ttcggcggcg ttgctgagcg
    47521 caggcaaacc taaactcgcc gcaaccatcc ctaataagag atgcggccag aagtagcgtt
    47581 taccaaactg tcgccagcgc gtcagtattc cactcacgtt attgccatcc cgatcatatt
    47641 caaacgtatt tagcgcacaa atcttatcat taaagcctgc agtccacagc acgaatgaag
    47701 ataagttgtg cggaaaagtg cttaagaaaa cagcgttcgc accgtttttt atagctctta
    47761 taaaattcaa aaaaaaacga ctggttcacc tggccggaga gagtgccaga tttgccagtc
    47821 gaattttata cgacagtata aatgtcgtta tgccagtaca gctgaaggcg ctttgaaggc
    47881 caacggcagt tctgcgtcgt cctggaaggt cacatattcc caggcttcct gtttcgccag
    47941 gacagcctgc agcagtttgt tattcagtgc atgaccggat ttataagcgg taaatgcacc
    48001 aataatattg tgaccacaca tgaacaagtc accgatcgca tcgagcattt tgtgacgcac
    48061 aaattcgtct tcaaaacgca ggccgtcttc gttcagtacg cgataatcgt caacaacgat
    48121 ggcacaatcg aagctgccgc ccaggcacaa accacgggac tgcagatatt cgatatcacg
    48181 catgaaaccg aacgtacgcg cacggctgat ctggcgcata aacgcatcag cggagaagtt
    48241 catcgcatag cgctggttgc tggaatcaat agccggatgg ttaaaatcga tggtgaaatc
    48301 cagcgaaaaa ccattgtacg gcttaaattc agcccactta tcgccatctt cgacacgaac
    48361 agtctctttg atgcgaacaa attttttggc gcagttcaac tcgtcgatac cggcgtcaag
    48421 cagcaggtat acaaacggag cggcgctgcc gtccatgatc gggatttccg gcgcgttaac
    48481 ttcgataaca atgttatcga tgcccaagcc cgcgagagca gcattgaggt gctctacggt
    48541 tgaaatccgt acatcatgct cgttgaccag acacgtacag agcatggtat cacgcacaga
    48601 tttggcatcg gccgggaaat ctaccggtgg attcaagtcg gtgcgacgat agatgacccc
    48661 ggtgttggcc ggcgcagggc gtaacgtcag ggtgactttc ttgccggtat gtaaaccgac
    48721 acccgtcgcc tgaacgatac gtttaagtgt cctttgtttg atcatcgtat tatctcgcca
    48781 aattacctat ccaaccgaag tgtactatac attcggcggg ccagtttagc acaaagagcc
    48841 tcgaaaccca aattccagtc aattcttaat cagcttgctt acgcaggaat gctgggatat
    48901 ccagataatc cggctctttc gcagtttgcg gcgcattgtc attcacgact ttagcaaccg
    48961 gcttctgctc ctgggtcagc ggagccatcc catgctgctg gtagcgatcc atcactggct
    49021 gctgaacctg cttattggtc accagagtga tttcaggacg tttgtccatg ccgatacctg
    49081 tcgcaacaac ggttacgcgc agctcgtcat tcatatccgg gtcaagagaa gtaccgataa
    49141 ccacagtcgc gttgtcggaa gcaaatgcac ggatggtgtt acctaccgtt tcgaactcat
    49201 ccagacgcag gtcgaagccc gccgtgatgt taaccagcac gccgcgcgcg ccagacaggt
    49261 cgatatcttc cagcagcgga gaagagatag ccatttcagc agcttcttcc gcacggtctt
    49321 cacccctcgc cacgccagaa cccatcattg cgtagcccat ctcagacatt acggtgcgta
    49381 cgtctgcaaa gtccacgttc atcaaacccg gacgagtaat cagttcagcg ataccttgca
    49441 cagcgccttt cagtacatcg ttcgctgcgc caaacgcatc cagcagggag ataccgcggc
    49501 ccagaacttt cagcagtttg tcgttcggga tagtgatcag agagtccaca tgcttggaca
    49561 gttcagtgat cccctgctcc gcgaatgcca tacgcttctt gccttcaaag ttgaaaggct
    49621 tagtgacgac agcaacggtc aggataccca aatcttttgc cacttcagcg acgactggtg
    49681 ctgcacctgt accggtacca ccacccatac ccgcagcaat aaagaccatg tctgcacctt
    49741 ccagcgccgc acgcaatgca tcgcgatcct catcagccgc attgcggcca acttctggat
    49801 tagcgccagc gcccagtcct ttggtgatac cgctaccgat ttgaatcgtc tgtccaaccg
    49861 ctgttttacg cagcgcttgt gcatcggtat ttaccgcgaa gaattcaaca ccttcaatgc
    49921 gctcgcgcac catgtgttca acagcattac cgccgccgcc gccgacgccg atgactttaa
    49981 tcaccgcgtc attggtaagt tccattggtt caaacatagt ttctctccga tttgtgcctg
    50041 tcgcctgagg ccgtaatcat cgtcggcctc ataaaaatta aaactctttt cgcagccaac
    50101 tattgagtcg cttgatccac gagccaactg atgctgtaac acgtttttct acttcagctt
    50161 caccgttaag atgtgactct ttcccatagt gaagcaatcc caccgccgtc gaataatacg
    50221 gctcctgagc ataatccgtt aaaccggtaa tgttcagcgg cgcgccgata cgcacttgcg
    50281 tatgaaacac gcgctgagca caggctgcaa gaccttcgat ctgcgctgcg ccaccggtta
    50341 atacaatgcc tgccgccagg tgatgtttaa ccccttgttg gcgaagcttt tcctgcaact
    50401 gcaatatctc ttcgttgacc aggttgagca gctcggtata gcgcggctcg atcacctctg
    50461 ccagtgtctg acgttgcaga ctccgtggcg gacgaccacc tacgctcggc acttccacgc
    50521 tctcatcttt tccaacgatg gaacccagcg cacaaccgtg gcgaacttta atcgcttcgg
    50581 cgtcgcttgg cggcgtgcca aaggcgtaag cgatatcact ggtcacgaca ttgccagcat
    50641 aaggaattac cttagtgtgg cgcaatgccc caccggtata aacggcgata tccattgtac
    50701 caccaccgat atcgacgacg cagacaccca gttcacgttc atcttccgtc aataccgaat
    50761 aacttgatgc cagtccggca aatatcagtt ggtcaacttt cagcccacaa cgttcaaccg
    50821 ctttgacgat gtttttcgcc atatcgttgt gacatgtgat caggtgcact tttgcctgca
    50881 tccgcacgcc cgaaagtcct accggattct tgatcccttc ctgatagtca atcgcatact
    50941 cttgcgggat cacatgcagc acacgatgct catcgcgcac acgcaccgat ttcgcggtat
    51001 ggacgacgtt ttccacatct tcttgcgtca cttcttcttc agaaataggc accataccaa
    51061 tttcattctg gcagctgatg tgcttaccag aaagcgccag atataccgaa gagatctgac
    51121 aatctgccat caattctgcc tggtcaatgg cgcgttgtac gcacttgacc acggattcga
    51181 ggtcgttcac cccgccttta tccataccac gcgacgggca gctgcccacg ccaatgatat
    51241 tgaccatacc gtcgggcaga acttccccta ctaaagcggc aaccttcgcg gtaccaatct
    51301 ccagtcctac taccagtttt ctgtccgtcg ccttgatcat tgttgttctg cctgtgcctg
    51361 attttgttgc tgagtagatt cctctggcgg caagggcgcc cagcctactg ccgctccaga
    51421 gtcataacgc aaatcaacgt agctaatccg tttgccatcg gtttgcgcct gctgctgtaa
    51481 aaccggataa agttctacaa agcgagccaa acgtttcatc gtatcgcccc ggccaagatt
    51541 gagcttaata tcgttattca gcgtcaactg ccaggaacgc cgcgcggtca tcgccgcttc
    51601 cttcagagta aatctgtcct ttgccagcat ctgccccatt tcgcgatagc cctgcaacac
    51661 ttcattggcg ctgccttccg ggccatacag cattggaagc acctgcttgc tggtgcgttc
    51721 tggcggcacg ctgaaggtat ttccttccgc gtctaccata tgttgatcat tccaccgcgc
    51781 aatcggcaca tattcaacca gatgaatctt caattcatca ggccactgct ttctgacgct
    51841 cacctgctta atccacggca ggcgttgttc tatttgcgtc tggatgatgt tgacatcctg
    51901 ggtcataaag gtacccggct cacccaatgc caggatcgac tgccggatat cgtcattacg
    51961 tgtgtaatgg cgttcaccgg tcaacaccag ctttgagagc ggcaggcgtt gcgcatcttc
    52021 catccagccc aacacgaccc agccgctcac caacactgtc gttaaaacgg tcagcaggaa
    52081 aaggatcccc gccagacgcg ttccattatt gcggcgagaa gaaacctctt cttcgctgtt
    52141 tcgcgtgttc agagcagcct gcgacatatt agtccgccag ttccagaatt cgtactacca
    52201 actgcgagaa gctcatacct gcctgacgtg ccgccatcgg caccaggctg tggctggtca
    52261 tacccggtga ggtattggct tccagcagat aaaactgtcc atcgctgtcc agcataacgt
    52321 caatacgtcc ccatcctttg caacctaacg tcgtccatgc tttcagcact aatgcctgca
    52381 aattggcctc ttgtgacgct tccagacctg cggggcagaa atactgtgtc tcatcagaga
    52441 gatacttcgc ctcataatca tagaaggttc cggacggttg aatacgtatt gacggtaaaa
    52501 tttcttcacc gagtatcgca accgtgaact ccggcccact tagccatttt tcaatcaata
    52561 cttcttcatc gtgctgaaat gccaatctta atgcatcttg tagagcattt tctgctacta
    52621 cttttgacat tcccacactg gaaccttcgc ggctcggctt aacgataacc ggcaaaccca
    52681 gagcagaaat ttctgctaac tgcttatcgc tcaggccttt ttcaaactct gcgcgggtta
    52741 acgctaccca cggcgcgacc ggtaaaccgg caccttgcca tagaagtttg ctgcgtagtt
    52801 tatccattga aagcgcagat gccatcactc cgcttccggt ataaggcaag cccatcagct
    52861 cgagcatccc ctgcagcgta ccatcttcac cgccgcgacc gtgtagcgcg ataaacactt
    52921 tctgaaagcc catcgacttc agttgcgtca cgtcgacttc tttcgggtcg acaggatacg
    52981 cgtcaatacc gccttcacgc agtccggcta acaccgctgc gccagaattc agagaaactt
    53041 cccgctcagc ggaggtccca cccaacagga ccgcgatttt atcagtcatg ttgttcttcc
    53101 tccggagttt gcggcttcag tttgatttca gctaaagaac gggcaatttt tccaatatta
    53161 ccagccccct gaacgagaat caggtcgtta ccggttaata ccggtgccag catctcggct
    53221 acccgcgccg gatccggcac aagaatggga tcaattttcc cacgtccacg aattgtgcga
    53281 cacagcgaac ggctgtccgc tcccggaatt ggcgcttcgc cagccggata cacttccagc
    53341 atcaacaggg tatcaacctg cgtcagcaca ttggcgaaat catcatacag gtcgcgcgta
    53401 cgggtaaaac ggtgcggctg aaacagcatt accaggtttt tatccggcca gcctgcgcgc
    53461 gccgctttaa tggtggcgtc cacttccgtc gggtggtggc cgtagtcatc gaccagcatt
    53521 gccgtaccgc ttttaccatt cactggctcc agcgggaatt caccgaggaa atcaaaacgg
    53581 cgaccagtcc cctggaagct ttcaagcgcc cgcaaaatag cctcgtcgtc aatgccctct
    53641 tccgtagcaa ccgcaaccgc agctgcggcg ttcagcgcgt tatgacgacc tggcgcattc
    53701 agggtgacgc gcatcggctc tttgtcctgg cgcagcagcg taaagtgccc ctgcgggcca
    53761 atctgctgat aatcttctac acgcacgtcg gcatcttcgc tgaagccgta agtcgtggtc
    53821 tgacgcccca ctcgcggtaa caattcgcgg atcaccggat catcaacaca catcaccgca
    53881 cgaccgtaaa acggcaggtt gtgcagaaaa ttaataaaag tctgttttaa attctcaaag
    53941 tcgccctggt aggtatccat gtggtcggct tcgatattgg tgacaatcgc caccatcggt
    54001 tgcagatgca ggaacgatgc atcactctca tctgcttcgg caatcaggta ccgaccatgc
    54061 cccaaacgcg catgaacccc cgccgctttt accagcccgc cgttaacgaa ggttgggtcg
    54121 agccccgctt ctgcgtagat gctggaaacc atcgcggtgg ttgtcgtttt gccgtgcgtt
    54181 ccggcaatgg cgatgccatg acgaaaacgc attaactcag ccagcatttc ggcacgacgg
    54241 atcaccggaa tacgcgcttc atgagcggcg acaatttccg ggttatcggc agaaatcgcg
    54301 ctggaaacaa cgaccacgct ggcatcacgt acgttttccg ggcgatggtt gaaataaatc
    54361 gtcgcaccca gattcattaa ctgctgcgtg accggatttg gcgctaaatc ggaaccactg
    54421 atctgataac cttcattggc cagaacttcg gcaataccgc ccataccggc accaccaatg
    54481 ccgacaaaat gtatgtgccg aacgcgacgc atttcgggca cgatggaacg cagttttgcc
    54541 aattgttgtg tattcattct ttacgccatt aacttcttaa attcatacga tgcaaaaggc
    54601 atcgctacaa ttacgcccgg gcaacccggc tcacttcatt tgccactcgc tcggtggcat
    54661 ccggaatgga tgcagcgcgg gcgcgttctg ccatggttaa taaggtttct cgcgaccacc
    54721 cggccagggt gttggcgaca acatccacgc taagctgtgg ctgctcgata attttggctg
    54781 cgcccgcttt ttccagcggt agcgcattcc agtattgctg gcggtcttta tgttgaaacg
    54841 gcacaaacaa cgccggtagt cctgccgcgg cgatttcact caccgttaac gcaccggagc
    54901 ggcaaacgac gacatccgcc cacgcatacg ccgccgccat atcatcaata aattccgtca
    54961 ctttatgctg cggttgcccc gcttcggcat acgcctgttc aacggattgt tgcgaacctt
    55021 tgccgctctg atgccagata gtgactgaat cacccagttt cgcagcaacc tgcggcattg
    55081 tctggttaag aatgcgtgcg ccctgagaac cacccactac cagcacacga accggacctt
    55141 cacgtccagc caaacgttgc tgcggcaacg gcagcgccaa cacatcggta cgcaccgggt
    55201 tacccactac ttccgcatta gggaaagcac ctggaaacgc ctgcatcact ttggtggcaa
    55261 tcttcgccag ccatttattg gttaagcccg caataccgtt ttgttcatga agtacaaccg
    55321 gaatgcctaa cgaccacgcg gccagaccac ctggacctga cacgtagcct cccataccga
    55381 gcaccacgtc aggtttgtac gctttcataa tcgcccgcgc ctgacgccag gcgttgaaga
    55441 tacgcagcgg ggcagctatc agtgctttta taccttttcc acgcagacca gagatacgaa
    55501 tgaaatcaat ttcgatgcca tgttttggca ctaagtccgc ttccatacgg tcggcagtcc
    55561 ccagccagcg aacttgccaa ccctgagcca ttagatggtg cgcaaccgcc agtcccggga
    55621 atacatgtcc accggttccg cctgccatca ccattaatcg ctttccttga ccactcatcg
    55681 tgaacctcgt acaaacgcct gcgctttctc cagacgcgtt tcataatcaa tacgcaacag
    55741 catcatgatg gctgtcgaca taatcagtaa gctcgaacca ccgtaactga tcagcggcaa
    55801 tgtcagacct ttggtcggta acatccccgc cgccgcgcct acgttaacca gcgcctggaa
    55861 gctaaaccag atgccaatag aacaggcgag aaaaccggaa aaacggtggt caatttctaa
    55921 tgctttacgg ccaatcgaca tcgcgcgaaa agcgacgaag aataccatta aaagtgccag
    55981 caccacaccg acatacccca gttcttcgcc gataatggcg aaaataaagt cagtgtgcgc
    56041 ttccggcaga tactccagtt tttgtaccga gttacctaaa ccttgccccc aaagttcgcc
    56101 gcgaccaaac gccatcagcg attgcgttaa ctgatagccg ctgccaaagg gatcttccca
    56161 cgggttccag aatgcggtaa cacggcggat acggtacggt tcggcgagta tcagcaacac
    56221 aaccgctgaa atgcccatac cgataatggc aatgaactgc cacaatttcg ctcccgccag
    56281 gaacaacatc gccagcgtag tcacaaacaa caccaccacc gtaccaaggt ctggctgtgc
    56341 cagcagtaac actgccaaca ccagaatcac gcccatcggt ttcaggaagc cgcgcaggtt
    56401 attacgtact tcgtcgcctt tacgcaccag atagttggcg atatagcaaa acagcgacag
    56461 ttttgtcagc tccgcaggct ggatacgcag caaaccgaga tcgatccaac gcgatgcccc
    56521 tttaaccgag ctacccacta ccaggacgat catcagcagg atgatagatc cgagcagcat
    56581 cgtggcactg tagcgttgcc agaactccat cggcagacgc agcgtaatga tcgccagaat
    56641 aaacgccaaa atcagataga caccatcacg cttcgcgaag aagaacggat cgttggttaa
    56701 gcgttgccct atgggcattg acgccgaggt caccatgata aagccaatcg ccgcgaggcc
    56761 gaaggtcagc cacagtaagg tgcgatcgta catgatcagg ctgtcggtat ctttttcccg
    56821 cgagcccatc acccagccct ttagcgccgt ggagatccag accaggatac tgaatcctgg
    56881 caggcgcggc attttcaggc gagggagaga taaacgcatc aacctaactc cttcgccaga
    56941 cgggcaaact cattgcctcg ttgttcaaag ttcttgaact gatcaaggct ggcacaggct
    57001 ggggagagca gaaccatatc gcccggctga acacgcggag ccagcaagcg catcgcctgt
    57061 tccatagttt cggtttgttc tgccacttcc gggcgtagcg ccgccagctg cgcgccgtca
    57121 cgaccgaaac aatacagacg tacgttatcg ccattcaggt aacgcgccag tgggctaaag
    57181 tccgccgatt taccatcgcc acccagcaac aaatgcagtg tgccgtctac gtgcaggcca
    57241 ttcagcgccg cttccgtact gccgacgttg gtcgctttcg aatcgttaat ccaacgtacg
    57301 ccgttatgct ccagcacaac ttcaaagcga tgcggcagac cagtgaatgt ggttaacgct
    57361 ttcaggctgc tggcacgcgg taaccctgca gcatctgcca gcgccagcgc cgccagcgca
    57421 ttggtgtagt tatgctgccc ggaaagtttc atctctttca cattcagcac tttctcgcct
    57481 ttaacccgca gccaggtttc gccctgctga tgattcaggt gatagtcacc catgttgacg
    57541 ccaaagctga cgcagcgttc atccgcaccg cgaatcggca ttgttaaggc atcatcagca
    57601 ttaaccacgc aaactttcgc gttttcgtaa atgcgcagtt ttgctgcacg atactgttgt
    57661 aaaccaaacg gatagcgatc catatgatct tcagtcacgt tcagaatggt cgctgctacc
    57721 gcctgtaagc tggaggtggt ttccagctgg aagctcgaca gttccagcac gtacagttca
    57781 cactcatcat ccagtagcat caacgcaggc aggccaatat tgccacccac accaacgtta
    57841 acccccgccg ctttcgccat ttcacccact agcgtggtga ccgtgctttt gccgttagaa
    57901 ccggtaatcg ccacaatcgg tgcttgtgct tcgcgacaga acagctcgat atcgccaacg
    57961 atttcgattc cggcatcagc ggcagcgctt aaggatggat gcgccagtgc aataccggga
    58021 ctggcgacaa tcagatctgc cgccatcagc cattcatcat tcagactgcc cgtgtggcgt
    58081 tctacggctt cgggtaattt atccaggcca ggcggtgtca tacgcgtatc cataacgcgc
    58141 ggcgtcacac cgcgagcgag gaaaaagtcc acgcaggaaa gcccggtgag gcccaggccg
    58201 ataatgacga catttttacc ctgataatca gccatgatta acgtaccttc agcgttgcca
    58261 gaccaatcag aaccagcatc agcgaaataa tccagaaacg cacaatgacg cgcggttccg
    58321 gccagccttt cagttcatag tggtgatgaa tcggtgccat gcggaaaata cgttgtccgc
    58381 gcagtttaaa ggagccgacc tgcaggatga cagaaagcgt ttctaccacg aacacgcccc
    58441 ccataatcac cagcaggaat tcctgacgta gcagtacggc gataatgcct aacgcaccac
    58501 ctaacgccag cgaacctaca tcgcccataa agacctgcgc cggataggtg ttaaaccaca
    58561 ggaagcccag tcctgccccg actatcgcgg tacagacaat aaccagttcc ccggcgtgtc
    58621 gcagatacgg tatatgcaag tagctggcaa agttcatatt gccggtcgcc cacgccacca
    58681 gcgcaaaacc accggcgaca aatacggtcg gcataattgc caggccgtcg agaccatcgg
    58741 tcaggtttac cgcgttgcca gtacccacaa tgacgaagta agccagcaga atgtagaaca
    58801 gccccagctg cggcatcaca tctttaaaga atgggaccac cagctgcgtt gcgggcgtgt
    58861 ctttgccggc aaggtacagg gcgaaggcga cacccagcgc aatgaccgac atccagaaat
    58921 acttccaacg agcgatcaac cctttggtgt ctttacgcac cactttgcga taatcatcaa
    58981 caaagccaat aacaccgtaa cctaccagca ccaccaacac gcaccagacg tacggattgg
    59041 acgggtaagc ccacagcagt acggagatca caatcgccgt caggatcata atcccgccca
    59101 tggtcggcgt accgcgcttg ctgaagtgtg attcaggacc gtcgttacgc accacctgac
    59161 caaaggaaag tttttgcaaa tgagcaatca tacgcgggcc catccacaat gagatgaaca
    59221 gcgcggtcag caggctgacg atggcgcgaa acgtcagata ggaaaagacg ttaaagccgg
    59281 aataatattt gaccaaatgt tcggccagcc aaactaacat gtcccattct cctgtaaagc
    59341 gcgtactacc tcttccatgg cggcactacg tgaaccctta actaaaatcg taattacctg
    59401 ttgctcagca atcagtaatt taagacgcgt aattaacgca gttttatcag caaaatgttc
    59461 gccaacgccg ctggcggtgc tgatagcatg gctttgttta cccacgctta acacgcggtc
    59521 aataccagca gcttttgccg cctcgcccac ctgtacatgg caggcttcgc tttcagcgcc
    59581 cagttccgcc atatcgccca ccaccagcac gcggtagccc ggcatttcag ccagtacctg
    59641 gactgctgca gtcattgaac cgacattggc gttgtaggag tcgtcgagca gcaactggtt
    59701 ttctgccagt tggatgggga acagacggcc tggaacagct ttcagatttg ccagccccgc
    59761 tttgatagca tcaagcgttg cgcccacgga catggagagc gcagcggctg ccagcgcatt
    59821 cgcaatattg tgacgccccg gcaacggcag cagaacatcg acgctaccgg ttggggtttg
    59881 tagggtaaat tccgtaccgt gcgaggtcac atggatattg gtggcggtga aatcgctgtt
    59941 ggcggcattg ggtgagaaac gccacacttt gcgtgagcca attacgctct gccagttcag
    60001 ccagtcgttg ttgtcggcgt tcataatggc gataccgttt tccggcaggc cgctaaagat
    60061 ttcacctttc gctttcgcga cacccgcaag cgagccaaaa ccttccagat gcgccgctgc
    60121 caggttgttg accagcgcag cttccgggcg agtcagactc acagtccagg ctatttcgcc
    60181 ctgatggttc gcgccaagtt caataactgc gtaatcgtat tccggcgtta agcgcaacag
    60241 cgtcatcggt acaccgatgt cgttgttgag attgcctgcc gtataaagcg tgttgccgca
    60301 ctggcttaaa atcgccgccg tcatctcttt aacggaggtt ttgccggagg accccgtcag
    60361 agcaaccacg cgcgccggaa cttgctggcg aacccatgca gccagttcac caaacgccag
    60421 acgcgtatcc ttgacgatta actgcggcag gtcgatgtcc agcggacggc taaccagtag
    60481 tgcgcctgcg ccgccagctt tcgcctggtc ggcaaaatcg tgggcatcaa aacgttcgcc
    60541 tttcagggca acaaacaggc agcccggcgt cagttttcgg gtatcagtgg ttacagcatc
    60601 aagggtgata tctgcacctt gcagttcacc gttgagaatg tcggtaattt ggctaagggt
    60661 tacgctaatc atgcaatcac ccccagcaga cgcgccaccg tgacgcgatc ggagtagtcc
    60721 agacgctgat tgccaacaat ctggtaatct tcatggcctt tgcccgcgac cagtaccaca
    60781 tcattctctt tagcctgcat aacggcgcaa gtcaccgctt cagcacggcc ttccatcact
    60841 ttggcatgtc cggcatctaa cattcccgcc agaatatcgt tgatgatggc acgcggttct
    60901 tcggtacgcg ggttatcgtc cgtcaccacc gccacgtcag caaactcttc ggcaattgcg
    60961 cccatcagtg gacgcttacc tttatcgcga tcgccaccac agccaaagac acaccacagc
    61021 ttgcccgcac agtgcagacg cgccgcctgt aaggcttttt ccagtgcatc cggcgtatgc
    61081 gcgtaatcca ccaccaccgt cggtttgcct ggcgcagtga acacttccat acgtccgcaa
    61141 accggttgca gacgcgcggc ggttttcagc agatcagcca gtggatagcc gagtgccaac
    61201 agtgtcgcca gcgcgagcag caggttgctg acgttaaaag cgcccatcag atggctttca
    61261 atttcgccat cgccccaact tgagctaaag cgaatcgtcg caccgctgtc gtgatagttc
    61321 acttcggtcg ctttcaacca gcgtccgtga cagttcggat taatatgatc ttccattgat
    61381 accgcaaccg cgtccggcag ttttgccagc cagcggcggc ccacttcatc gtcggcgtta
    61441 ataatcgcct gaccgcaatg atgctcagaa taaagcagcc atttcgcggc ttcgtagtgt
    61501 tccatatcac catgataatc aaggtgatcg cggcttaagt tggtaaagac cgacgccgca
    61561 aatttcaatg ccgccacacg gtgctgtacc agcccgtggg aggaaacttc cattgcgcaa
    61621 aacgtcgcgc cctgatccac cagccccgcc agctcatgct gaacatcgac tgccgaaccg
    61681 gttgtatttt ctgtcgggat cactttcccc agcaggccgt taccaacggt gcccattacc
    61741 gcgctggttt cgccaagcag ttggctccac tgcgccaaca gctgggtagt cgtggttttg
    61801 ccgttggtgc ccgttacgcc cacgagacgt aaattgtcag agggttcatg gtaaaagcgg
    61861 cccgccagtg cagataaacg ctcgttgagc tggctgagat agatgaccgg tacgccgtgc
    61921 atttcacgga tttcaccatc ggtcgcctca tctttcgcct ctgcaataat ggcagccaca
    61981 ccttgcgcta tcgcctgcgg gatatatcga cgcccgtccg cctgatgacc tactacagct
    62041 acaaagagat cgcccgccgc agccacacgg ctgtcgagtg tcatctctcg cagtgctcgc
    62101 gaaggtgcgt ctggcaccca cggagcaaga aggtcgcgca aattacgatc tgccacctgt
    62161 cccctcgcct tgattaatca caaattcatt tttatcgccc gttgtcagcg catccggctc
    62221 gatgttcatg gtacgcaata cgccgcccat gatggcacca aagaccggcg cggaaacggc
    62281 gccgccgtag tatttacccg cctgcggatc gttgataaca acaaccagcg cgaagcgcgg
    62341 ctgactcgca ggcgcaacgc ctgcggtata agcaatatat ttattgatgt agcgaccgtc
    62401 cggcccgacc tttttcgcgg taccggtttt aatggcgata cgatagcctt taatcgccgc
    62461 cttcacgccg ccgccgcctg gtagcgccac gctttccatc atatgcacca cagtgcggac
    62521 aatggattcc gggaagacac gttcaccggg aaccgggggg tcaactttgg taatcgacag
    62581 tgggcgataa atgccgtagc tgccgatagt tgcgtagact cgcgctaact gtaatggtgt
    62641 taccattagc ccgtagccga aagagaaggt ggccctctct atgtcagacc accgttgttt
    62701 ttgaggatat aagccactgc gttctccgac caaccccaaa ttggtcgctt ttcccagtcc
    62761 aaaacgtgag taagtatcta ctaacgctga ggacggcatc gctaacgcca gcttggaaac
    62821 accgacgtta ctcgacttct gtaatacccc ggtcagggtt aattcgctgt agcgtgccac
    62881 gtctttgatt tcgtggccgt taattcgata aggaatggta ttgagtaccg agttttcccg
    62941 caccacgcca cgttgcaacg cggtcattac caccatcggt ttaaccgttg agcccggttc
    63001 aaacacgtcg gtgatggtac ggttacgcat cgcctctttc ggcgtgccgc tcagattgtt
    63061 agggttgtat gacgggctgt tagccatcgc cagcacttca ccggtgttga catccaccag
    63121 cacggcgcta ccagattcag ccttgttaaa ggccaccgcg ttgttcagtt cgcgataaac
    63181 cagcgcctgc aggcgttcat caatactcag cgccaggttg tgcgctgcct ggctgtcagt
    63241 agaagaaata tcttcaatta cgcgaccata gcggtcttta cgcacaatgc gctcacccgg
    63301 ctgcccggta agccatttat cgaaactctt ctcaacgccc tcaatccctt gactatcgac
    63361 gttagtaaag ccgatgaggt gagcagtcac ttcgccggac ggatagtaac ggcgagactc
    63421 ttcacgcaga tgaatccccg gcagtttcag ttttttgatg tagtccgcca tgtcagggtt
    63481 cacctgacgc gccagataaa taaagcgccc tttcgggttg gcgttaatgc gggctgaaag
    63541 ctgatccagc ggaatattga gcgcgttagc cagtgccttc cagcggtcac cgacgctgat
    63601 accgccagcg tcatgcactt ctttcgggtc agcccaaatc gcttttaccg gcacgctcac
    63661 cgctaacggg cgaccagaac ggtcagtaat catgccgcgg gaggtggaaa cttgctgaac
    63721 gcgaagagaa cgcatgtcgc cctctttcac cagcatatcc ggggagataa cttgtaacca
    63781 cgctacgcgt ccgagcagaa aagccagcgc caggagaata cagccgcata acaacgcaaa
    63841 acgccaactg ataaagttgg catgttcttc ctgacgtttt ggtttctgcg ttttcgccgc
    63901 tgctttcatg cgtcgcgttt atccttattt ttgcactacg atattttctt gtgacggatc
    63961 aacatgctgc atttgcagct tttccgtggc gatcctttcc acccggctat ggtcgccgag
    64021 cgcattctct tcaaggatca ggttgcgcca ttcaatgtct aaagcatctc gctccagcac
    64081 cagttgttcg cgctgagcgg tcagtaaacg ggtatggtgc gccgtggtta ccacagtcac
    64141 cgccgtcaaa ataatgcaaa tgaacaggca gagtggcagc ttcccaaatc gcaaaagatc
    64201 gtcaccgata acaccaggca atgcatggcg ctcgtggctt cccatcgatc ctttaacttt
    64261 gcttagagct tctgtcactc tgctgatcat gcattcgtcc tctctgcaat acgcagaact
    64321 gaactacggg cacgagggtt ctcagccacc tcttcttcgc ccggcattaa cttgcctagt
    64381 gctcgcagct gacggccacc cagttttttg agctgctctt cagtcatcgg taaccctgcc
    64441 ggaacttgcg gaccgcggct gttttcacgc ataaaacgtt tcacaatacg gtcttccagc
    64501 gagtggaagc tgatgatcga aagccgccca cccggggcca gcacgttgag cgagcttttt
    64561 agcgcctgct ctatctcctc cagttcactg tttacccaaa tgcgcaccgc ctggaaggta
    64621 cgggtcgcgg gatgtttaaa cttatctttc accggcgttg cagcagccac gacttccgcc
    64681 agttctttgg tgcgggtcat cggctgttcg cggttacgct cgacaatggc gcgggcaatg
    64741 cgtttggcaa aacgctcttc accataggtt ttcaataccc aggcgatatc ggcttcttct
    64801 gcggtttgta gccattcagc ggctgactgc ccacgggttg ggtccatacg catgtccagc
    64861 ggaccatcgc gcataaagga aaagccacgt tcagcatcat caagttgcgg tgaagagacg
    64921 ccaagatcga ggagaatgcc gtcgatcttg ccgataagat cgcgctcggc aacgtattcg
    64981 cccagcgcgg agaaaggtcc gtggatgatg gagaagcgcg gatcatcaat agtcttcgca
    65041 acggcgatag cctgcgggtc gcgatcgatc gccagcaaac gcccctcttc gccaagctgc
    65101 gagaggatca gacgtgagtg accaccgcga ccaaaagtcc catcaatgta gatgccatca
    65161 ggacggatat tgaggccatt aacggcttca tccagcagca ccgtagtatg tttatagttt
    65221 tccatcattt tatagagaca agtcctgcag tcgctccgat aagtctccgg tagccaactg
    65281 ctctgcgtcg atatcttcct tgacctgttg atgccaggtt gtttcatccc acagctcaaa
    65341 cttgttgaac tgtccaacca gcatcacttc ttttgtcagc ccggcatgtt gccgcagtac
    65401 tggcgcgatt aacaatcgac ctgcgccatc catctgacat tcgctggcat gacctaacag
    65461 taggcgctgc acacggcgct caaccgggtt catgctcgac agacgcgata atttttgctc
    65521 gataatttcc cattcaggca gggggtaaag cagcaggcac gggtgataaa tgtcaatggt
    65581 gcaaaccatt tgaccggcag cgttctcaag cagctgttcc cgataacggg taggcactga
    65641 taagcgccct ttgctgtcga gattgactaa cgttgctccc cggaacatgc cagcctcacc
    65701 ccttattccc actttgcccc acaatttccc actgaaagga gtttacggag ctgaggaaaa
    65761 gcttgtcaag ccagtcacaa ggcataccga ggtaaaaaac ccgatgttta cggctaatat
    65821 cagcgttgtt tattttacgt ccaacgtgcg aagcaaatta acgttatgaa tagctgtaag
    65881 aaaaaatccc tcatcgtcat caccgtttta aaatgactca ctattttcca cagcaaatat
    65941 aaagtgtcag tttgcgacgc gagcggcatt ttaggacata tcttccccgg ttaacagtcc
    66001 ttgttacgtc tgtgtggcgc ttgatgccag cgggtttgcg caaaagcaaa gaaaagtgtt
    66061 tgttaaatcg gcaattcatc gccgcatgta acaaaataat gcaaaaacgc gctgtcgata
    66121 tcacttaatt attgtgaatt tcagctggtg agttaattaa cgggcgggtt taaaagcatt
    66181 tatcaataat agtcaggaat agtcttattt actttaagca tattgatgtc cagtcccgta
    66241 ctctacgcgc cagagggaaa ttcacctggc gcgtattttt gttcgcggct tagctacggc
    66301 tgagcacgcc gcggcgatag agattacgtt taatgcgcgt taaaccaggt tttggcttac
    66361 gcggttcgtc caggcttgcc aggacaatct ccagcacacg ctctgcgaca tcgcggtgac
    66421 gttgagccac tgccagcacc ggacactgta agaagtcgag cagttcgtta tcgccaaagg
    66481 tggcaattgc caggtcagaa ggcagtttgc cgtcgcgacg cagcgtgaca tccatcactc
    66541 cttgcaacaa cgcaaacgac gttgtgaaca gcgcctgcgg catcggatgc gtttccagcc
    66601 atttttcgaa taactgggca gccgcctccc gctcatagct gttggcatac aggaaatgca
    66661 cttcgcgcgg atcatctttc caggcagtac ggaaaccttg ttcacgcagg aagctgacag
    66721 aaagctccgg tagcgcacca agataaagca ccgtctcggc gggaaactta cgtaactctt
    66781 ccgccagcat ttcggcatca tcctgatcgg caccaaccac gctggtgaag tgttcacgat
    66841 cgagggcgcg gtccagcgcg acaatcggga acgggtcgtt agcccagcgt tgataaaaag
    66901 gatgctcagg aggcaacgac gtcgaaacaa taatggcatc aacctgacgc tgtaaaaggt
    66961 gctcaatgca ccgcatttcg ttgtctggct gatcttctga gcaggcaatc agcagttgat
    67021 aaccccgttg ccgcgcctgg cgttcaagat agttagcgat gcgggtatag ctggtgttct
    67081 ccagatcggg gatcacaaga ccaatagaac gtgtgcgtcc agcacgaagc ccagctgcca
    67141 cggcgttcgg gtggtaattg tgctcacgca ccacagccat gactttttca acggttttgt
    67201 cgctcacacg gtattgcttc gctttgccgt taataacata gcttgcagtg gtccgcgaca
    67261 ctcccgccag ccgagcgatt tcatccagtt tcacaattgc cccttgcgta aaatgtaaaa
    67321 accatagcca ttgtactggt atgggttaaa ttcattaaca tctaagcgca gaaaattaac
    67381 tgcggcaact gcttttattc caggttccca ctgatttcgc aaaaaaagcc caacgtgaca
    67441 tgttgggctg taaattgcgc attgagatca ttctcaacgc attattttat cgccgcgcga
    67501 aagtccgacc acaccagagc gagcaacctc cacaattttc gccacatcgc gaatcgatgc
    67561 taaaaatgca tcaagcttac cgctggtgcc tgctaattga acggtataaa gcgagggtgt
    67621 gacatcgata atttgcccac ggaatatttc cgtattacgt ttcacttcgt cacgcccgta
    67681 accgctggcc tgaattttca ccagcatgat ttcccgctca acatgcgcgc cctgccccaa
    67741 ctcactcacg cgcaagacat cgaccagttt gtgtaattgc ttttcgatct gctcaagtac
    67801 tttttcatcg cccacggtct ggatggtcat acgcgataat gtcggatcgt cggttggcgc
    67861 aacggtcagg ctttcaatgt tgtagccacg ctgggaaaaa aggccaatca cgcgggataa
    67921 cgcgcctgat tcattttcga gtaagactga taatatccgg cgcataatca ggttctctcc
    67981 gttttgctta accacatttc atccattccg cccccgcgaa tctgcatcgg gtagacgtgc
    68041 tcgctgccat cgacggtaac atcaacaaac accaggcgat tattgcgcac ctgttccagc
    68101 gcctcgctaa gtttgctttc cagctcatgc ggatgagaaa tctggatccc gacatgccca
    68161 taggcttccg ccagacggac gaaatcgggt agcgattgca tataagattg tgaatgacgg
    68221 ccggaataga tcatgtcctg ccactgcttc accatcccca gatagcggtt attgagattc
    68281 accaccagta cgggcaactc gtattgcaac gcggtagaca gttcctggat gttcatctga
    68341 atactgccgt cgccagtgac gcaaaccacg gtttcttctg gcaacgccat tttgacgccc
    68401 agtgccgcag gtaaaccaaa acccatcgtg ccgaggccac cggaattgat ccagcgacgc
    68461 ggtttgtcga atggataata aagtgcagca aacatctggt gctgcccgac atcggacgtc
    68521 acgtaagcgt ctcccttcgt caaccgccaa agagtctcga tcaccgcctg cggtttaatc
    68581 ttttcactgt gagtgtcata tttcaggcac tgacgagcgc gccactgttc aatttgctgc
    68641 caccagtcgc ggatctcatc cagtggttga tgggcggatt cttgcgacaa gagttcaagc
    68701 atttgttcga ggacctggcg agcatccccc acaatcggga tatccgcagt cacggtttta
    68761 gaaatggaag taggatcaat atcgatatgc agaacagtgg catttgggca gtactttgcc
    68821 agattgttcg tcgttcggtc atcaaatcgt accccgacgg cgaaaatcac atccgcgtta
    68881 tgcatcgtca tattggcttc gtaggtaccg tgcattccca gcatgcccag tgcctgacga
    68941 tgcgttgccg gaaacgcccc cagccccatc aatgagcaaa caacgggcag attcaacgcc
    69001 tccaccgttt ctttcaactg ctgatggcag cccgccgtga ttgccccacc gcctacgtag
    69061 acaaccggtt tttttgccgc taccagcgtt tgcagagcac gcttaatttg ccctttatgt
    69121 ccggtagtag tgggattgta agaacgcata ctgaccgact ccggccagac atagggtaat
    69181 ttgttcgccg gattaagaat atctttcggt aaatcaacga ctactggtcc tgggcgacca
    69241 cttgccgcca gccagaaagc ctttttcagc acctgcggaa tgtcttccgt ttgcttaacc
    69301 agaaaactgt gtttaaccac cggtcgcgaa atccccacca tgtcgcactc ctgaaaggca
    69361 tcgtaaccta tcaacgaggt cgctacctgc ccggaaagga caactaatgg aatggaatcc
    69421 atataagcgg tggcgatgcc agtaatcgca ttggtcgccc ctggacccga cgttaccagc
    69481 acgacgccga cttccccggt cgcgcgcgcc aggccatcgg ccatatgcac cgccgcctgc
    69541 tcatgacgaa ctaatacatg atcaatacca cccacggtat gcaatgcatc ataaatatca
    69601 aggactgcgc ctccgggata accgaatact tgtttaacgc cctgatcgat aagcgatcgg
    69661 acgaccatct cggctccaga caacatctcc atggcctgcc tcactgtttg acggaaaaaa
    69721 tgtgtaaaac acattaaccg tccgatcttg cttaagcaat tggcagccag agacataaac
    69781 acggggtaat aagaataaac aggaggaaag gtgaaaagaa acgataaaat cctccattac
    69841 agaggattaa attgataata aatcggctga atcccacaac ttacagcaat ttctctattt
    69901 ttttaattaa tcctaaaata gagagcccac acattcagaa taaaattcta cattcaataa
    69961 aaaatgcaga ataaaccaga cattcatgtc tgacctattc tgcaatcagt tagcgtttgc
    70021 aaattgagac taattgctct tccatccact gatggccttt atcgcgcccg gcagcttcat
    70081 gccaggagag ataacaggtt ctgctgtttt gttttaacgg cagcggtaat acctgtaatt
    70141 ctaaggattc agcgaactct tcagccagcc aacgcggcgc aatagcgacc aaatgcgttt
    70201 gcgacaccac gctaagtacg ctcatcattg ccatgccctg atacgcgata ctggcttgct
    70261 tatctaccgt gtcataccaa ggttgactaa atgacgcgaa acgatcgagc gaaaccgccg
    70321 catgttgttc gttataaaca tcatgtttca gtaacgggcc cttaattgtt ggatgatttt
    70381 tgctggctac cagcaccatt tcatctttaa ataatggtac gctggtaaat tcaggacgat
    70441 ggaagtcttc ataactaatc acaaactccg tttcctgata acgcagctga tgttcagtgt
    70501 tctgatttaa tgaagacttg aacataacat gtatatttgg cgcaatctgc tcaatgtgat
    70561 tataaatctg cgaggtcaga atgctgtcta acgggctgca aacacaaaga tgaaatacac
    70621 gttcactgct cgcgggttca aaacctgaac caggcaattc attttgtact agttgcaatg
    70681 cctgacgaac tgaaccaaaa agttgaaatg cgcgagcagt cggttgaata ccacggccat
    70741 aacgaacaaa aagctcgtca ttaaacatca ccttcaggcg tgcaacagcg ttactgaccg
    70801 caggttgcga cattcccaga acatgagcgg cacgagtaat gttttgctcc tgcatcacgg
    70861 catcgaaaac ggttaataag ttgagatcga ccatgcgtag ctgtggtttg cttaactccg
    70921 ccgtctctgg atgatctgtt tgtacctctg gcatacttaa ctccactgtc acacttaact
    70981 ccctttccct tattggaatg cagagaaata atcctgaaga atatgattta tcatgcatat
    71041 aaaataagaa aaagcaaaat gagtaaaatt cggaaaacat aaagatacgg gttctgataa
    71101 aaacagaatc cattgccgtg gaatgagtca tttaccacag cataataatc cataatgttt
    71161 ttgttgcgaa aacaatctaa tcataactac
//
LOCUS       DAPOAV010000010        69621 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.010, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000010 DAPOAV010000000
VERSION     DAPOAV010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 69621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69621
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.010"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            77..595
                     /locus_tag="RN951_000819"
     CDS             77..595
                     /locus_tag="RN951_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HDX2525867.1"
                     /translation="MMKFKKCLLPVAMLASFTLAGCQSNADDHAADVYQTDQLNTKQE
                     TKTVNIISILPAKVAVDNSQNKRNAQAFGALIGAVAGGVIGHNVGSGSNSGTTAGAVG
                     GGAVGAAAGSMVNDKTLVEGVSLTYKEGTKVYTSTQVGKECQFTTGLAVVITTTYNET
                     RIQPNTKCPEKS"
     gene            611..1150
                     /locus_tag="RN951_000820"
     CDS             611..1150
                     /locus_tag="RN951_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5384 family protein"
                     /protein_id="HDX2525868.1"
                     /translation="MKKVFLCAILASLSYPAIASSLQDQLSAVAEAEQQGKNEEQRQH
                     DEWVAERNREIQQEKQRRANAQAAANKRAATAAANKKARQDKLDAEASADKKRDQSYE
                     DELHSLEIQKQKLALAKEEARVKRENEFIDQELKHKAAQTDVVQSEADANRNMTEGGR
                     DLMKSVGKAEENKSDSWFN"
     gene            complement(1245..2822)
                     /gene="guaA"
                     /locus_tag="RN951_000821"
     CDS             complement(1245..2822)
                     /gene="guaA"
                     /locus_tag="RN951_000821"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDX2525869.1"
                     /translation="MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEA
                     QIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEA
                     SNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFVTVAST
                     ESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAV
                     ARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDM
                     FGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQ
                     GTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELG
                     LPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTV
                     FLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGIS
                     RVVYDISGKPPATIEWE"
     gene            complement(2891..4357)
                     /gene="guaB"
                     /locus_tag="RN951_000822"
     CDS             complement(2891..4357)
                     /gene="guaB"
                     /locus_tag="RN951_000822"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004151980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HDX2525870.1"
                     /translation="MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPM
                     LSAAMDTVTEARLAIALAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLP
                     TTTLREVKELTERNGFAGYPVVTEENELVGIITGRDVRFVTDLNQPVSVYMTPKERLV
                     TVREGEAREVVLAKMHEKRVEKALVVDDEFHLIGMITVKDFQKAERKPNACKDEQGRL
                     RVGAAVGAGAGNEERVDALVAAGVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGG
                     NVATAAGARALAEAGCSAVKVGIGPGSICTTRIVTGVGVPQITAVADAVEALEGTGIP
                     VIADGGIRFSGDIAKAIAAGASAVMVGSMLAGTEESPGEIELYQGRSYKSYRGMGSLG
                     AMSKGSSDRYFQSDNAADKLVPEGIEGRVAYKGRLKEIIHQQMGGLRSCMGLTGCGTI
                     DELRTKAEFVRISGAGIQESHVHDVTITKESPNYRLGS"
     gene            4519..5889
                     /gene="xseA"
                     /locus_tag="RN951_000823"
     CDS             4519..5889
                     /gene="xseA"
                     /locus_tag="RN951_000823"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HDX2525871.1"
                     /translation="MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPAS
                     GHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESM
                     QPAGEGLLQQKYEQLKAKLQAEGLFDQQYKKPLPSPAHCVGVITSKTGAALHDILHVL
                     KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANQRNECDVLIVGRGGGSLEDLWSFND
                     ERVARAIFASRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQS
                     TRQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLERLQKRMSFALENQL
                     KRTGQQQQRLTQRLNQQNPQPKIHRAQTRIQQLEYRLAETLRVQLSATRERFGNAVTH
                     LEAVSPLSTLARGYSVTTATDGNVLKKVKQVKAGEMLTTRLEDGWIESEVKNIQPVKK
                     SRKKVH"
     gene            complement(5886..6101)
                     /locus_tag="RN951_000824"
     CDS             complement(5886..6101)
                     /locus_tag="RN951_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417005.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDX2525872.1"
                     /translation="MELHCPQCQHVLDQDNGHARCPSCGEIIEMKALCPDCHQPLQVL
                     KACGAVDYFCQHGHGLISKKRVEFVLA"
     gene            complement(6170..7642)
                     /gene="der"
                     /locus_tag="RN951_000825"
     CDS             complement(6170..7642)
                     /gene="der"
                     /locus_tag="RN951_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417006.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HDX2525873.1"
                     /translation="MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGR
                     AEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAI
                     AKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLL
                     PWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTL
                     TNRILGEERVVVYDMPGTTRDSIYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVI
                     KTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQV
                     KETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAV
                     EDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMG
                     SPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKNK"
     gene            complement(7760..8938)
                     /gene="bamB"
                     /locus_tag="RN951_000826"
     CDS             complement(7760..8938)
                     /gene="bamB"
                     /locus_tag="RN951_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamB"
                     /protein_id="HDX2525874.1"
                     /translation="MQLRKLLLPGLLSVTLLSGCSLFNSEEDVVKMSPLPTVENQFTP
                     TTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALNADDGKEIWSVSLAEKDG
                     WFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAWQTKVAGEALSRPVVSDG
                     LVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESAPATAFGAAVVGGDNGRVSA
                     VLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQ
                     IMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWAQSDLLHRLLTSPVLYN
                     GNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGKLLIQAKDGTVYSITR
                     "
     gene            complement(8949..9569)
                     /gene="yfgM"
                     /locus_tag="RN951_000827"
     CDS             complement(8949..9569)
                     /gene="yfgM"
                     /locus_tag="RN951_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ancillary SecYEG translocon subunit YfgM"
                     /protein_id="HDX2525875.1"
                     /translation="MEIYENENDQVEAVKRFFAENGKALAVGVILGVGALIGWRYWNS
                     HQVDSARSASLAYQNAVTAVSEGKPDSIPAAEKFAAENKNTYGALASLELAQQFVDKN
                     ELEKAAAQLQQGLADTSDENLKAVINLRLARVQVQLKQADAALKTLDTIKGEGWAAIV
                     ADLRGEALLSKGDKQGARSAWEAGVKSDVTPALSEMMQMKINNLSI"
     gene            complement(9587..10861)
                     /gene="hisS"
                     /locus_tag="RN951_000828"
     CDS             complement(9587..10861)
                     /gene="hisS"
                     /locus_tag="RN951_000828"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HDX2525876.1"
                     /translation="MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLP
                     IVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQE
                     QRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEH
                     VTLELNSIGSLEARANYRDALVAFLEQHKEKLDEDCKRRMYTNPLRVLDSKNPEVQAL
                     LNDAPALGDYLDEESREHFAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNSL
                     GSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLV
                     ASGADTQSAAMALAERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEV
                     ANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG"
     gene            complement(10972..12090)
                     /gene="ispG"
                     /locus_tag="RN951_000829"
                     /gene_synonym="gcpE"
     CDS             complement(10972..12090)
                     /gene="ispG"
                     /locus_tag="RN951_000829"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HDX2525877.1"
                     /translation="MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEAT
                     VNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGV
                     DCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLES
                     AMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAV
                     KSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQ
                     EFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGV
                     RKDRLDNNDMIDQLEARIRAKASQLDEARRIDVQQVEK"
     gene            complement(12117..13130)
                     /gene="rodZ"
                     /locus_tag="RN951_000830"
     CDS             complement(12117..13130)
                     /gene="rodZ"
                     /locus_tag="RN951_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HDX2525878.1"
                     /translation="MNTEATHDQNEALTTGARLRNAREQLGLSQQAVAERLCLKVSTV
                     RDIEEDKAPADLASTFLRGYIRSYARLVHIPEEELLPGLEKQAPLRAAKVAPMQSFSL
                     GKRRKKRDGWLMTFTWLVLFVVIGLSGAWWWQDHKAQQEEITTMADQSSAELSSNSEQ
                     GQSVPLNTSTTTDPATTSTPPASVDTTATNTQTPAVTAPAPAVDPQQNAVVSPSQANV
                     DTAATPAPTATTTPDGAAPLPTDQAGVTTPAADPNALVMNFTADCWLEVTDATGKKLF
                     SGMQRKDGNLNLTGQAPYKLKIGAPAAVQIQYQGKPVDLSRFIRTNQVARLTLNAEQS
                     PAQ"
     gene            complement(13415..14569)
                     /gene="trmG/rlmN"
                     /locus_tag="RN951_000831"
     CDS             complement(13415..14569)
                     /gene="trmG/rlmN"
                     /locus_tag="RN951_000831"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA
                     large subunit methyltransferase RlmN"
                     /protein_id="HDX2525879.1"
                     /translation="MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQ
                     VMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQ
                     RVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVG
                     AAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPA
                     LDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVT
                     IEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVL
                     MSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV"
     gene            complement(14719..15150)
                     /gene="ndk"
                     /locus_tag="RN951_000832"
     CDS             complement(14719..15150)
                     /gene="ndk"
                     /locus_tag="RN951_000832"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HDX2525880.1"
                     /translation="MAIERTFSIIKPNAVAKNVIGNIFARFEAAGFKIVGTKMLHLTV
                     EQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLEGENAVQRHRDLLGATNPANALAGT
                     LRADYADSLTENGTHGSDSVESAAREIAYFFGEGEVCPRTR"
     gene            complement(15299..17611)
                     /gene="pbpC"
                     /locus_tag="RN951_000833"
     CDS             complement(15299..17611)
                     /gene="pbpC"
                     /locus_tag="RN951_000833"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417014.1"
                     /note="penicillin-binding protein 1C; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase PbpC"
                     /protein_id="HDX2525881.1"
                     /translation="MPRLLTKRGCWITLAAAPFLLFLAAWGADKLWPLPLHEVNPARV
                     VVAQDGTPLWRFADADGIWRYPVTIEDVSPRYLEALINYEDRWFWKHPGMNPFSVARA
                     AWQDLTSGRVISGGSTLTMQVARLLDPHPKTFGGKIRQLWRALQLEWHLSKREILTLY
                     LNRAPFGGTLQGIGAASWAYLGKSPANLSYSEAAMLAVLPQAPSRLRPDRWPERAEAA
                     RNKVLERMAVQGAWSREQVKESREEPIWLAPRQMPQLAPLFSRMMLGKSKSDKIVTTL
                     DAGLQRRLEELAQNWKGRLPPRSSLAMIVVDHIDMRVRGWVGSVDLNDDSRFGHVDMV
                     NAIRSPGSVLKPFVYGLALDEGLIHPASLLQDVPRRTGDYRPGNFDSGFHGPISMSEA
                     LVRSLNLPAVQVLEAYGPKRFAAKLRNVGLPLYLPNGAAPNLSLILGGAGAKLEDMAA
                     AYTAFARHGKAGKLRLQPDDPLLERPLMSSGAAWIIRRIMADEAKPLPDSALPRVAPL
                     AWKTGTSYGYRDAWAIGVNARYVIGIWTGRPDGTPVVGQFGFASAVPLLNQVNNILLS
                     RSANLPEDPRPNSVTRGVICWPGGQSLPEGDGNCRRRLATWLLDGSQPPTLLLPEQEG
                     INGIRFPIWLDENGKRVAADCPQARQEMINVWPLPLEPWLPASERRAVRLPPASTICP
                     PYGHDAKLPLQLTGVRDGAIIKRLPGAAEATLPLQSSGGAGERWWFLNGEPLTERGRN
                     VTLHLTDKGDYQLLVMDDVGQIATVKFVMQ"
     gene            complement(17612..22573)
                     /gene="yfhM"
                     /locus_tag="RN951_000834"
     CDS             complement(17612..22573)
                     /gene="yfhM"
                     /locus_tag="RN951_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha2-macroglobulin"
                     /protein_id="HDX2525882.1"
                     /translation="MKKLRVAACMLMLALAGCDNNDNAPTAVKKDAPSEVTKAASSEN
                     ASSAKLSVPERQKLAQQSAGKVLTLLDLSEVQLDGAATLVLTFSIPLDPDQDFSRVIH
                     VVDKKSGKVDGAWELSDNLKELRLRHLEPKRDLIVTIGKEVKALNNATFSKDYEKTIT
                     TRDIQPSVGFASRGSLLPGKVVEGLPVMALNVNNVDVNFFRVKPESLPAFISQWEYRN
                     SLANWQSDKLLQMADLVYTGRFDLNPARNTREKLLLPLGDIKPLQQAGVYLAVMNQAG
                     RYDYSNPATLFTLSDIGVSAHRYHNRLDIFTQSLENGAAQQGIEVSLLNEKGQTLTQA
                     TSDAQGHVQLENDKNAALLLARKDGQTTLLDLKLPALDLAEFNIAGAPGYSKQFFMFG
                     PRDLYRPGETVILNGLLRDADGKALPNQPIKLDVIKPDGQVLRSVVSQPENGLYHFTW
                     PLDSNAATGMWHIRANTGDNQYRMWDFHVEDFMPERMALNLTGEKTPLTPKDEVKFSV
                     VGYYLYGAPANGNTLQGQLFLRPLREAVSALPGFEFGDIAAENLSRTLDEVQLTLDDK
                     GRGEVSTESQWKETHSPLQVIFQGSLLESGGRPVTRRAEQAIWPADALPGIRPQFASK
                     SVYDYRTDSTVKQPIVDEGSNAAFDIVYSDAQGVKKAVSGLQVRLIRERRDYYWNWSE
                     DEGWQSQFDQKDLIENEQTLDLKADETGKVSFPVEWGAYRLEVKAPNEAVSSVRFWAG
                     YSWQDNSDGSGAVRPDRVTLKLDKASYRPGDTIKLHIAAPTAGKGYAMVESSEGPLWW
                     QEIDVPAQGLDLTIPVDKTWNRHDLYLSTLVVRPGDKSRSATPKRAVGVLHLPLGDEN
                     RRLDLALETPAKMRPNQPLTVKIKASTKNGEKPKQVNVLVSAVDSGVLNITDYVTPDP
                     WQAFFGQKRYGADIYDIYGQVIEGQGRLAALRFGGDGDELKRGGKPPVNHVNIVAQQA
                     LPVTLNEQGEGSVTLPIGDFNGELRVMAQAWTADDFGSNESKVIVAAPVIAELNMPRF
                     MASGDTSRLTLDITNLTDKPQKLNVALTASGLLELVSDSPAAVELAPGVRTTLFIPVR
                     ALPGYGDGEIQATISGLALPGETVADQHKQWKIGVRPAFPAQTVNYGTALQPGETWAI
                     PADGLQNFSPVTLEGQLLLSGKPPLNIARYIKELKAYPYGCLEQTASGLFPSLYTNAA
                     QLQALGIKGDSDEKRRASVDIGISRLLQMQRDNGGFALWDKNGDEEYWLTAYVMDFLV
                     RAGEQGYSVPTDAINRGNERLLRYLQDPGMMSIPYADNLKASKFAVQSYAALVLARQQ
                     KAPLGALREIWEHRADAASGLPLLQLGVALKTMGDATRGEEAIVLALKTPRNSDERIW
                     LGDYGSPLRDNALMLSLLEENKLLPDEQYTLLNTLSQQAFGERWLSTQESNALFLAAR
                     TIQDLPGKWQAQTSFSAEPLTGEKTLNSNLNSDQLATLQVRNSGDQPLWLRVDASGYP
                     QSAPLPANDVLQIERHILGTDGKSKSLDSLRSGDLVLVWLQVKASNSVPDALVVDLLP
                     AGLELENQNLANGSASLEQSGGEVQNLLNQMQQASIKHIEFRDDRFVAAVAVDEYQPV
                     TLVYLARAVTPGTYQVPQPMVESMYVPQWRATGAAEDLLIVRP"
     gene            22780..23625
                     /gene="sseA"
                     /locus_tag="RN951_000835"
     CDS             22780..23625
                     /gene="sseA"
                     /locus_tag="RN951_000835"
                     /EC_number="2.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417016.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-mercaptopyruvate sulfurtransferase"
                     /protein_id="HDX2525883.1"
                     /translation="MSTTWFVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLN
                     GHIPGAVFFDIEALSDHTSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAP
                     RAWWMLRTFGVEKVSILGGGLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDV
                     LLASHENTAQIIDARPAARFNVEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDE
                     LDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARADLP
                     VEPVK"
     gene            complement(24118..24894)
                     /gene="sseB"
                     /locus_tag="RN951_000836"
     CDS             complement(24118..24894)
                     /gene="sseB"
                     /locus_tag="RN951_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708361.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enhanced serine sensitivity protein SseB"
                     /protein_id="HDX2525884.1"
                     /translation="MSETKNELEDLLEKAATEPAHRPAFFRTLLESTVWVPGTAAQGE
                     AVVEDSALDLQHWEKEDGTSVIPFFTSLEALQQAVEDEQAFVVMPVRTLFEMTLGETL
                     FLNAKLPTGKEFMPREISLLIGEEGNPLSSQEILEGGESLILSEVAEPPAQMIDSLTT
                     LFKTIKSVKRAFICSIKENEEAQPNLLIGIEADGDIEEIIQATGSVATDTLPGDEPID
                     ICQVKKGEKGISHFITEHIVPFYERRWGGFLRDFKQNRII"
     gene            complement(25036..26319)
                     /gene="pepB"
                     /locus_tag="RN951_000837"
     CDS             complement(25036..26319)
                     /gene="pepB"
                     /locus_tag="RN951_000837"
                     /EC_number="3.4.11.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311416.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase PepB"
                     /protein_id="HDX2525885.1"
                     /translation="MTEAMKITLSTQPADARWGEKATYSINNDGITLHLNGADDLGLI
                     QRAARKIDGLGIKHVQLSGEGWDADRCWAFWQGYKAPKGTRKVEWPDLDDAQRQELDN
                     RLMIIDWVRDTINAPAEELGPSQLAQRAVDLISNVAGDRVTYRITKGEDLREQGYMGL
                     HTVGRGSERSPVLLALDYNPTGDKEAPVYACLVGKGITFDSGGYSIKQTAFMDSMKSD
                     MGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIITYRNGKKVEVMNT
                     DAEGRLVLADGLIDASAQKPELIIDAATLTGAAKTALGNDYHALFSFDDALAGRLLAS
                     ASQENEPFWRLPLAEFHRSQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYQQGW
                     LHIDCSATYRKAPVEQWSAGATGLGVRTIANLLTA"
     gene            complement(26497..26697)
                     /gene="iscX"
                     /locus_tag="RN951_000838"
     CDS             complement(26497..26697)
                     /gene="iscX"
                     /locus_tag="RN951_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004104502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein IscX"
                     /protein_id="HDX2525886.1"
                     /translation="MGLKWTDSREIGEALYDAYPDLDPKTVRFTDMHQWICDLEDFDD
                     DPQASNEKILEAILLVWLDEAE"
     gene            complement(26709..27044)
                     /gene="fdx"
                     /locus_tag="RN951_000839"
     CDS             complement(26709..27044)
                     /gene="fdx"
                     /locus_tag="RN951_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015683702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISC system 2Fe-2S type ferredoxin"
                     /protein_id="HDX2525887.1"
                     /translation="MPKIVILPHQDLCPDGAVLEANSGETILDAALRNGIEIEHACEK
                     SCACTTCHCIVREGFDSLPESSEQEDDMLDKAWGLEPESRLSCQARVTDEDLVVEIPR
                     YTINHAREH"
     gene            complement(27046..28896)
                     /gene="hscA"
                     /locus_tag="RN951_000840"
     CDS             complement(27046..28896)
                     /gene="hscA"
                     /locus_tag="RN951_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S protein assembly chaperone HscA"
                     /protein_id="HDX2525888.1"
                     /translation="MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETL
                     ADHEGRHLLPSVVHYQQQGHSVGYDARTNAALDTANTISSVKRLMGRSLADIQQRYPH
                     LPYQFQASENGLPMIETAAGLLNPVRVSADILKALAARATEALAGELDGVVITVPAYF
                     DDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISIL
                     RLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIPDRSDNRVQRELLDAAIAAKI
                     ALSDADSVTVNVAGWQGEISREQFNELIAPLVKRTLLACRRALKDAGVEADEVLEVVM
                     VGGSTRVPLVRERVGEFFGRPPLTSIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVI
                     PLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRS
                     LARFALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDSE
                     IASMIKDSMSYAEQDVKARMLAEQKVEAARVLESLHGALAADAALLSAAERQVIDDAA
                     AHLSEVAQGDDVDAIEQAIKNVDKQTQDFAARRMDQSVRRALKGHSVDEV"
     gene            complement(28913..29428)
                     /gene="hscB"
                     /locus_tag="RN951_000841"
     CDS             complement(28913..29428)
                     /gene="hscB"
                     /locus_tag="RN951_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone HscB"
                     /protein_id="HDX2525889.1"
                     /translation="MDYFTLFGLPARYQLDTQALSLRFQDLQRQYHPDKFASGSQAEQ
                     LAAVQQSATINQAWQTLRHPLMRAEYLLSLHGFDLASEQHTVRDTAFLMEQLELREEL
                     DEIEQAKDEARLESFIKRVKKMFDTRHQLMVEQLDNEAWDAAADTVRKLRFLDKLRSS
                     AEQLEEKLLDF"
     gene            complement(29524..29847)
                     /gene="iscA"
                     /locus_tag="RN951_000842"
     CDS             complement(29524..29847)
                     /gene="iscA"
                     /locus_tag="RN951_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly protein IscA"
                     /protein_id="HDX2525890.1"
                     /translation="MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEF
                     VDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCG
                     ESFHV"
     gene            complement(29864..30250)
                     /gene="iscU"
                     /locus_tag="RN951_000843"
     CDS             complement(29864..30250)
                     /gene="iscU"
                     /locus_tag="RN951_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold IscU"
                     /protein_id="HDX2525891.1"
                     /translation="MAYSEKVIDHYENPRNVGSFDNNDENVGSGMVGAPACGDVMKLQ
                     IKVNDEGIIEDARFKTYGCGSAIASSSLVTEWVKGKSLDEAQAIKNTDIAEELELPPV
                     KIHCSILAEDAIKAAIADYKSKREAK"
     gene            complement(30278..31492)
                     /gene="iscS"
                     /locus_tag="RN951_000844"
     CDS             complement(30278..31492)
                     /gene="iscS"
                     /locus_tag="RN951_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017459011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDX2525892.1"
                     /translation="MKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFG
                     WQAEEAVDIARNQIADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKT
                     EHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVV
                     QDIAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYV
                     RRKPRVRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMATEMERLRGLRNR
                     LWNGIKDIEEVYLNGDLEHGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLE
                     PSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSIGRLRDLSPLWEMYKQ
                     GVDLNSIEWAHH"
     gene            complement(31604..32092)
                     /gene="iscR"
                     /locus_tag="RN951_000845"
     CDS             complement(31604..32092)
                     /gene="iscR"
                     /locus_tag="RN951_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly transcriptional regulator
                     IscR"
                     /protein_id="HDX2525893.1"
                     /translation="MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQ
                     LFSRLRKNGLVSSVRGPGGGYLLGKDASSIAVGEVISAVDESVDATRCQGKGGCQGGD
                     KCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRTRIQDAIDVKL
                     RA"
     gene            complement(32393..33130)
                     /gene="trmJ"
                     /locus_tag="RN951_000846"
     CDS             complement(32393..33130)
                     /gene="trmJ"
                     /locus_tag="RN951_000846"
                     /EC_number="2.1.1.200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ"
                     /protein_id="HDX2525894.1"
                     /translation="MLQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDS
                     QAIALAAGASDVIGNAHIVDTLDEALAGCSLVVGTSARSRTLPWPMLDPRECGLKSVA
                     EAANTPVALVFGRERVGLTNEELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAW
                     LATQENGEQVEHEETPYPLVDDLERFYGHLEQTLLATGFIRENHPGQVMNKLRRLFTR
                     ARPESQELNILRGILASIEQQNKGNKA"
     gene            33249..34052
                     /gene="suhB"
                     /locus_tag="RN951_000847"
     CDS             33249..34052
                     /gene="suhB"
                     /locus_tag="RN951_000847"
                     /EC_number="3.1.3.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000553460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol-1-monophosphatase"
                     /protein_id="HDX2525895.1"
                     /translation="MHPMLNIAVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVD
                     KAAEAVIIDTIRKSYPQHTIITEESGELEGTDQDVQWVIDPLDGTTNFIKRLPHFAVS
                     IAVRIKGRTEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPFK
                     AKQYATTYINIVGKLFNECADFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGEL
                     LVREAGGIVSDFTGGHNYMLTGNIVAGNPRVVKAMLANMRDELSDALKR"
     gene            34197..35051
                     /locus_tag="RN951_000848"
     CDS             34197..35051
                     /locus_tag="RN951_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417029.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDX2525896.1"
                     /translation="MALPVNKRVPKILFILFVVAFCVYLVPRVAINFFYYPDDKIYGP
                     DPWSAESVEFTAKDGTRLQGWFIPSSTGPADNAIATIIHAHGNAGNMSAHWPLVSWLP
                     ERNFNVFMFDYRGFGKSKGTPSQAGLLDDTQSAINVVRHRSDVNPQRLVLFGQSIGGA
                     NILDVIGRGDREGIRAVILDSTFASYATIANQMIPGSGYLLDESYSGENYIASVSPIP
                     LLLIHGKADHVIPWQHSEKLYSLAKEPKRLILIPDGEHIDAFSDRHGDVYREQMVDFI
                     LSALNPQN"
     gene            35242..36522
                     /gene="csiE"
                     /locus_tag="RN951_000849"
     CDS             35242..36522
                     /gene="csiE"
                     /locus_tag="RN951_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary phase inducible protein CsiE"
                     /protein_id="HDX2525897.1"
                     /translation="MMPTLAPPSVLSAPQRRCQILLTLFQPGLTATMATFSELNGVDD
                     DIASLDISETGREILRYHQLTLTTGYDGSYRVEGTVLNQRLCLFHWLRRGFRLCPSFI
                     TSQFTPALKSELKRRGIARNFYDDTNLQALVNLCSRRLQKRFESRDIHFLCLYLQYCL
                     LQHHAGITPQFNPLQRRWVESCLEFQVAQEIGRHWQRRALQPVPPDEPLFMALLFSML
                     RVPDPLRDAHQRDRQLRQSIKRLVNHFRELGNVRFYDEQGLCDQLYTHLAQALNRSLF
                     AIGIDNTLPEEFARLYPRLVRTTRAALAGFESEYGVHLSDEESGLVAVIFGAWLMQEN
                     DLHEKQIILLTGNDSEREAQIEQQLRELTLLPLNIKHMSVKAFLQTGAPRGAALIIAP
                     YTMPLPLFSPPLIYTDLTLTTHQQEQIRKMLESA"
     gene            complement(36514..37653)
                     /locus_tag="RN951_000850"
     CDS             complement(36514..37653)
                     /locus_tag="RN951_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate MFS transporter"
                     /protein_id="HDX2525898.1"
                     /translation="MVLQSTRWLALGYFTYFFSYGIFLPFWSVWLKGIGLTPETIGLL
                     LGAGLVARFLGSLLIAPRVSDPSRLISALRVLALLTLLFAVAFWAGAHVAWLMLVMIG
                     FNLFFSPLVPLTDALANTWQKQFPLDYGKVRLWGSVAFVIGSALTGKLVTMFDYQVIL
                     ALLTLGVASMLLGFLIRPTIQPQGASRQQESTGWSAWLALVRQNWRFLACVCLLQGAH
                     AAYYGFSAIYWQAAGYSASAVGYLWSLGVVAEVIIFALSNKLFRRCSARDMLLISAIC
                     GVVRWGIMGATTALPWLIVVQILHCGTFTVCHLAAMRYIAARQGSEVIRLQAVYSAVA
                     MGGSIAIMTVFAGFLYQYLGHGVFWVMALVALPAMFLRPKVVPSC"
     gene            complement(37813..38703)
                     /gene="hcaR"
                     /locus_tag="RN951_000851"
     CDS             complement(37813..38703)
                     /gene="hcaR"
                     /locus_tag="RN951_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HcaR"
                     /protein_id="HDX2525899.1"
                     /translation="MELRHLRYFVAVAQALNFTRAAEKLHTSQPSLSSQIRDLENCVG
                     VPLLVRDKRKVALTAAGECFLQDALAILEQAENAKLRARKIVQEDRQLTIGFVPSAEV
                     NLLPKVLPMFRLRQPDTLIELVSLITTQQEEKIRRGELDVGLMRHPVYSPEIDYLELF
                     DEPLVVVLPVDHPLAHEKEITAAQLDGVNFVSTDPAYSGSLAPIVKAWFAQENSQPNI
                     VQVATNILVTMNLVGMGLGVTLIPGYMNNFNTGQVVFRPIAGNVPSIALLMAWKKGEM
                     KPALRDFIAIVQERLASVTA"
     gene            38839..40200
                     /locus_tag="RN951_000852"
     CDS             38839..40200
                     /locus_tag="RN951_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="HDX2525900.1"
                     /translation="MTTPSDLNIYQLIDTQNGRVTPRIYTDPDIYQLELERIFGRCWL
                     FLAHESQIPKPGDFFNTYMGEDAVVVVRQKDGSIKAFLNQCRHRAMRVSYADCGNTRA
                     FTCPYHGWSYGINGELIDVPLEPRAYPQGLCKSHWGLNEVPCVESYKGLIFGNWDTSA
                     PGLRDYLGDIAWYLDGMLDRREGGTEIVGGVQKWVINCNWKFPAEQFASDQYHALFSH
                     ASAVQVLGAKDDGSDKRLGDGQTARPVWETAKDALQFGQDGHGSGFFFTEKPDANVWV
                     DGAVSSYYRETYAEAEQRLGEVRALRLAGHNNIFPTLSWLNGTATLRVWHPRGPDQVE
                     VWAFCITDKAASDEVKAAFENSATRAFGPAGFLEQDDSENWCEIQKLLKGHRARNSKL
                     CLEMGLGQEKRRDDGIPGITNYIFSETAARGMYQRWADLLSSESWQEVLDKTAAYQQE
                     VMK"
     gene            40197..40715
                     /locus_tag="RN951_000853"
     CDS             40197..40715
                     /locus_tag="RN951_000853"
                     /EC_number="1.14.12.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate/cinnamic acid dioxygenase
                     subunit beta"
                     /protein_id="HDX2525901.1"
                     /translation="MSAQVSLELHHRISQFLFHEASLLDDWKFRDWLAQLDEEIRYTM
                     RTTVNAQTRDRRKGVQPPTTWIFNDTKDQLERRIARLETGMAWAEEPPSRTRHLISNC
                     QISETDIPNVFAVRVNYLLYRAQKERDETFYVGTRFDKVRRLEDDNWRLLERDIVLDQ
                     AVITSHNLSVLF"
     gene            40715..41035
                     /locus_tag="RN951_000854"
     CDS             40715..41035
                     /locus_tag="RN951_000854"
                     /EC_number="1.14.12.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-phenylpropionate/cinnamic acid
                     dioxygenase ferredoxin subunit"
                     /protein_id="HDX2525902.1"
                     /translation="MNRIYACPVADVPEGEALRIDTSPVIALFNVGGEFYAINDRCSH
                     GNASMSEGYLEDDATVECPLHAASFCLKTGKALCLPATDPLTTYPVHVEGGDIFIDLP
                     EAQP"
     gene            41032..41844
                     /gene="hcaB"
                     /locus_tag="RN951_000855"
                     /gene_synonym="phdD"
                     /gene_synonym="yfhX"
     CDS             41032..41844
                     /gene="hcaB"
                     /locus_tag="RN951_000855"
                     /gene_synonym="phdD"
                     /gene_synonym="yfhX"
                     /EC_number="1.3.1.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate-dihydrodiol/cinnamic
                     acid-dihydrodiol dehydrogenase"
                     /protein_id="HDX2525903.1"
                     /translation="MSDLHNESIFITGGGSGLGLALVERFIEEGAQVATLELSAAKVA
                     SLRQRFGEHILAVEGNVTCYADYQRAVDQILTRSGKLDCFIGNAGIWDHNASLVNTPA
                     ETLETGFHELFNVNVLGYLLGAKACAPALIASEGSMIFTLSNAAWYPGGGGPLYTASK
                     HAATGLIRQLAYELAPKVRVNGVGPCGMASDLRGPQALGQSETSIMQSLTPEKIAAIL
                     PLQFFPQPADFTGPYVMLASRRNNRALSGVMINADAGLAIRGIRHVAAGLDL"
     gene            41854..43056
                     /locus_tag="RN951_000856"
     CDS             41854..43056
                     /locus_tag="RN951_000856"
                     /EC_number="1.14.12.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylpropionate dioxygenase ferredoxin
                     reductase subunit"
                     /protein_id="HDX2525904.1"
                     /translation="MKEKTIIIVGGGQAAAMAAASLRQQGFTGELHLFSDERHLPYER
                     PPLSKSMLLEDSPQLQQVLPANWWQENNVHLHSGVTIKTLGRDTRELVLTNGESWHWD
                     QLFIATGAAARPLPLLDALGERCFTLRHAGDAARLREVLQPERSVVIVGAGTIGLELA
                     ASATQRRCKVTVIELAATVMGRNAPPPVQRYLLQRHQQAGVRILLNNAIEHVVDGEKV
                     ELTLQSGETLQADVVIYGIGISANEQLAREANLDTANGIVIDEACRTCDPAIFAGGDV
                     AITRLDNGALHRCESWENANNQAQIAAAAMLGLPLPLLPPPWFWSDQYSDNLQFIGDM
                     RGDDWLCRGNPETQKAIWFNLQNGVLIGAVTLNQGREIRPIRKWIQSGKTFDAKLLID
                     ENIALKSL"
     gene            43153..43575
                     /locus_tag="RN951_000857"
     CDS             43153..43575
                     /locus_tag="RN951_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417038.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HDX2525905.1"
                     /translation="MNTLRYFDFGAARPVLLLIARIAVVLIFIIFGFPKMMGFDGTVQ
                     YMASLGAPMPMLAAIIAVVMEVPAAILIVLGFFTRPLAVLFIFYTLGTAVIGHHYWDM
                     TGDAVGPNMINFWKNVSIAGAFLLLAITGPGAISLDRR"
     gene            complement(43623..44495)
                     /locus_tag="RN951_000858"
     CDS             complement(43623..44495)
                     /locus_tag="RN951_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase"
                     /protein_id="HDX2525906.1"
                     /translation="MTIYTLSHGSLKLDVSDQGGVIEGFWRDTTPLLRPGKKSGVATD
                     ASCFPLVPFANRVSGNRFVWQGREYQLQPNVEWDAHYLHGDGWLGEWQCVSHSDDSLC
                     LVYEHRSGVYHYRVSQAFHLTADTLTVTLSVTNQGAETLPFGTGWHPYFPLSPQTRIQ
                     AQASGYWLEREQWLAGEFCEQLPQELDFNQPAPLPRQWVNNGFAGWNGQARIEQPQEG
                     YAIIMETTPPAPCYFIFVSDPAFDKGYAFDFFCLEPMSHAPDDHHRPEGGDLIALAPG
                     ESTTSEMSLRVEWL"
     gene            complement(44507..45601)
                     /locus_tag="RN951_000859"
     CDS             complement(44507..45601)
                     /locus_tag="RN951_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HDX2525907.1"
                     /translation="MKINRIVNEGFMKTMLAAYLPGNSTVDLREVAVPTPGINQVLIK
                     MKSSGICGSDVHYIYHQHRATAAAPDKPLYQGFINGHEPCGQIVAMGQGCRHFKEGDR
                     VLVYHISGCGFCPNCRRGFPISCTGKGKAAYGWQRDGGHAEYLLAEEKDLILLPDALS
                     YEDGAFISCGVGTAYEGILRGEVSGSDKVLVVGLGPVGMMAMMLAKGRGAKRIIGVDM
                     LPERLAMAKQLGVMDHGYLATTEGLPQIIAELTHGGADVALDCSGNAAGRLLALQSTA
                     DWGRVVYIGETGKVEFEVSADLMHHQRRIIGSWVTSLFHMEKCAHDLTDWKLWPRNAI
                     THRFSLEQAGDAYALMASGKCGKVVINFPD"
     gene            complement(45634..46632)
                     /locus_tag="RN951_000860"
     CDS             complement(45634..46632)
                     /locus_tag="RN951_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX2525908.1"
                     /translation="MSASSLSLPQGKSVSLKQFVSRHINEIGLLVVIAILYLVFSLNA
                     PGFISLNNQMNVLRDAATIGIAAWAMTLIIISGEIDVSVGPMVAFVSVCLAFLLQFEV
                     PLAVACLLVLLLGALMGTLAGVLRGVFNVPSFVATLGLWSALRGMGLFMTNALPVPID
                     ENEVLDWLGGQFLGVPVSALIMIVLFALFVFISRKTAFGRSVFAVGGNATAAQLCGIN
                     VRRVRILIFTLSGLLAAVTGILLAARLGSGNAGAANGLEFDVIAAVVVGGTALSGGRG
                     SLFGTLLGVLVITLIGNGLVLLGINSFFQQVVRGVIIVVAVLANILLTQRSSKAKR"
     gene            complement(46657..48168)
                     /locus_tag="RN951_000861"
     CDS             complement(46657..48168)
                     /locus_tag="RN951_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDX2525909.1"
                     /translation="MFTATDAVPVAKVVAGNKRYPGVVALDNVNFTLNKGEVRALLGK
                     NGAGKSTLIRMLTGSERPDSGDIWIGETRLEGDEATLTRRAAELGVRAVYQELSLVEG
                     LTVAENLCLGQWPRRNGMIDYLQMAQDAQRCLQALGVDVSPEQLVSTLSPAQKQLVEI
                     ARVMKGEPRVVILDEPTSSLASAEVELVISAVKKMSALGVAVIYVSHRMEEIRRIASC
                     ATVMRDGQVAGDVMLENTSTHHIVSLMLGRDHVDIAPVAPQEIVDQAVLEVRALRHKP
                     KLEDISFTLRRGEVLGIAGLLGAGRSELLKAIVGLEEYEQGEIVINGEKITRPDYGDM
                     LKRGIGYTPENRKEAGIIPWLGVDENTVLTNRQKISANGVLQWSTIRRLTEEVMQRMT
                     VKAASSETPIGTLSGGNQQKVVIGRWVYAASQILLLDEPTRGVDIEAKQQIYRIVREL
                     AAEGKSVVFISSEVEELPLVCDRILLLQHGTFSQEFHSPVNVDELMSAILSVH"
     gene            complement(48191..49174)
                     /locus_tag="RN951_000862"
     CDS             complement(48191..49174)
                     /locus_tag="RN951_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDX2525910.1"
                     /translation="MPKKMRTTRNLLLMATLLGSALFARAAEKEMTIGAIYLDTQGYY
                     AGVRQGVQDAAKDSSVQVQLIETNAQGDISKESTFVDTLVARNVDAIILSAVSENGSS
                     RTVRRASEAGIPVICYNTCINQKGVDKYVSAYLVGDPLEFGKKLGNAAADYFIANKID
                     QPKIAVINCEAFEVCVQRRKGFEEVLKSRVPGAQIVANQEGTVLDKAISVGEKLIIST
                     PDLNAIMGESGGATLGAVKAVRNQNQAGKIAVFGSDMTTEIAQELENNQVLKAVVDIS
                     GKKMGNAVLAQTLKVINKQADGEKVIQVPIDLYTKTEDGKQWLATHVDGLP"
     gene            complement(49271..52552)
                     /locus_tag="RN951_000863"
     CDS             complement(49271..52552)
                     /locus_tag="RN951_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417044.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5107 domain-containing protein"
                     /protein_id="HDX2525911.1"
                     /translation="MTPVKVWQERVEIPTYETGPQDIHPMFLENRVYQGSSGAVYPYG
                     VTDTLSEQKTLKSWQAVWLENDYIKVMILPELGGRVHRAWDKVKQRDFVYHNEVIKPA
                     LVGLLGPWISGGIEFNWPQHHRPTTFMPVDFTLEAHEDGAQTVWVGETEPMHGLQVMT
                     GFTLRPERAALEIASRVYNGNATPRHFLWWANPAVKGGEGHQSVFPPDVTAVFDHGKR
                     AVSAFPIATGTYYKVDYSAGVDISRYKNVPVPTSYMAEKSQYDFVGAWCHDEDGGLLH
                     VANHHIAPGKKQWSWGHSEFGQAWDKSLTDNNGPYIELMTGIFADNQPDFTWLDAYEE
                     KRFEQYFLPYHSLGMVQNASRDAVIKLQRSERGIEWGLYAISPLNGYRLAIREIGKCN
                     ALLDDAVALMPATAIQGVLHGINPERLTIELSDADGNIVLSYQEHQPQELPLPDVAKA
                     PLSAQDITSTDEAWFIGQHLEQYHHASRSPFDYYLRGVALDPLDYRCNLALAMLEYNR
                     ADFPQAVAYATQALKRAHALNKNPQCGQASLIRASAYERQGQYQQAEEDFWRAVWSGN
                     SKAGGYYGLARLAARNGNFDAGLDFCQQSLRACPTNQEVLCLHNLLLVLSGRQDNARV
                     QREKLLRDYPLNATLWWLNWFDGRSESALAQWRGLCQGRDVNALMTAGQLINWGMPTL
                     ATEMLNALDCQRTLSLYLQASLLPKAERGELVAKAIDVFPQFVRFPNTLEEVAALESI
                     EECWFARHLLACFYYNKRSYNKAITLWQRCVEMSPEFADGWRGLAIHAWNKQHDYELA
                     ARYLDNAYQLAPQDARLLFERDLLDKLSGATPEKRLARLENNLEIALKRDDMTAELLN
                     LWHLTGQADKAADILATRKFHPWEGGEGKVTSQFILNQLLRAWQHLDARQPQQASELL
                     HAALHYPENLSEGRLPGQTDNDIWFWQAICANAQGDETEAMRCLRLAATGDRTINIHS
                     YYNDQPVDYLFWQGMALRLLGEQHTAQQLFSEMKQWAQEMAKTSIEADFFAVSQPDLL
                     SLYGDLQQQHKEKCLMVAMLASAGLGEVAQYESARAELTAINPAWPKAALFTTVMPFI
                     FNYVH"
     gene            52670..53863
                     /locus_tag="RN951_000864"
     CDS             52670..53863
                     /locus_tag="RN951_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311443.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDX2525912.1"
                     /translation="MRACINNQQIRHHNKCVILELLYRQKRANKSTLARLAQISIPAV
                     SNILQELESEKRVVNIDDESQTRGHSSGTWLIAPEGDWTLCLNVTPTSIECQVANACL
                     SPKGEFEYLQIDVPTPQALLSEIEKCWHRHRKLWPDRTINLALAIHGQVDPVTGVSQT
                     MPQAPWTTPVEVKYLLEEKLGIRVMVDNDCVMLALAEKWQNNSQERDFCVINVDYGIG
                     SSFVINEQIYRGSLYGSGQIGHTIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLK
                     SQPVNTQLDPEKLTTAQLIAAWQSGEPWITSWVDRSANAIGLSLYNFLNILNINQIWL
                     YGRSCAFGENWLNTIIRQTGFNPFDRDEGPSVKATQIGFGQLSRAQQVLGIGYLYVEA
                     QLRQI"
     gene            complement(53927..55180)
                     /gene="glyA"
                     /locus_tag="RN951_000865"
     CDS             complement(53927..55180)
                     /gene="glyA"
                     /locus_tag="RN951_000865"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDX2525913.1"
                     /translation="MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVM
                     QAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHSGSQAN
                     FAVYTALLEPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDATGHIDYADLEK
                     QAKEHKPKMIIGGFSAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVP
                     HAHVVTTTTHKTLAGPRGGLILAKGGSEELYKKLNSAVFPGGQGGPLMHVIAGKAVAL
                     KEAMEPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEAD
                     AALGRANITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWMCDVLDS
                     INDEAVIERIKGKVLDICARYPVYA"
     gene            55508..56698
                     /gene="hmpA"
                     /locus_tag="RN951_000866"
     CDS             55508..56698
                     /gene="hmpA"
                     /locus_tag="RN951_000866"
                     /EC_number="1.14.12.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NO-inducible flavohemoprotein"
                     /protein_id="HDX2525914.1"
                     /translation="MLDAQTIATVKATIPLLVETGPKLTAHFYDRMFTHNPELKEIFN
                     MSNQRNGDQREALFNAIAAYASNIENLPALLPAVEKIAQKHTSFQIKPEQYNIVGEHL
                     LATLDEMFSPGQEVLDAWGKAYGVLANVFINREAEIYNENASKAGGWEGTRDFRIVAK
                     TPRSALITSFELEPVDGGAVAEYRPGQYLGVWLKPEGFPHQEIRQYSLTRKPDGKGYR
                     IAVKREEGGQVSNWLHNHANVGDVVKLVAPAGDFFMAVADDTPVTLISAGVGQTPMLA
                     MLDTLAKAGHTAQVNWFHAAENGDVHAFADEVKELGQSLPRFTAHTWYRQPSEADRAK
                     GQFDSEGLMDLSKQEGAFSDPTMQFYLCGPVGFMQFAAKQLVDLGVKQENIHYECFGP
                     HKVL"
     gene            complement(56743..57081)
                     /gene="glnB"
                     /locus_tag="RN951_000867"
     CDS             complement(56743..57081)
                     /gene="glnB"
                     /locus_tag="RN951_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017373484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulatory protein P-II"
                     /protein_id="HDX2525915.1"
                     /translation="MKKIDAIIKPFKLDDVREALAEVGITGMTVTEVKGFGRQKGHTE
                     LYRGAEYMVDFLPKVKIEIVVPDDIVDTCVDTIIRTAQTGKIGDGKIFVFDVARVIRI
                     RTGEEDDAAI"
     gene            complement(57142..58476)
                     /gene="glrR"
                     /locus_tag="RN951_000868"
     CDS             complement(57142..58476)
                     /gene="glrR"
                     /locus_tag="RN951_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator GlrR"
                     /protein_id="HDX2525916.1"
                     /translation="MSHKPAHLLLVDDDPGLLKLLGLRLTSEGYSVVTAESGAEGLRV
                     LNREKVDLVISDLRMDEMDGMQLFAEIQKVQPGMPVIILTAHGSIPDAVAATQQGVFS
                     FLTKPVDKDALYQAIDDALEQSAPATDERWREAIVTRSPLMLRLLEQARLVAQSDVSV
                     LINGQSGTGKEIFAQAIHNASPRNSKPFIAINCGALPEQLLESELFGHARGAFTGAVS
                     NREGLFQAAEGGTLFLDEIGDMPAPLQVKLLRVLQERKVRPLGSNRDIDIDVRIISAT
                     HRDLPKAMARGEFREDLYYRLNVVSLKIPALAERTEDIPLLANHLLRQAAERHKPFVR
                     AFSTDAMKRLMTASWPGNVRQLVNVIEQCVALTSSPVISDALVEQALEGENTALPTFV
                     EARNQFELNYLRKLLQITKGNVTHAARMAGRNRTEFYKLLSRHELDANDFKE"
     gene            complement(58466..59179)
                     /gene="qseG"
                     /locus_tag="RN951_000869"
     CDS             complement(58466..59179)
                     /gene="qseG"
                     /locus_tag="RN951_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system QseEF-associated
                     lipoprotein QseG"
                     /protein_id="HDX2525917.1"
                     /translation="MRHIFQRLLPRRLWLAGLPCLALLGCVQNHNKPAIDTPAEEKIP
                     VYQLADYLSTECSDIWALQGKSTETNPLYWLRAMDCADRLMPAQSRQQARQYDDGSWQ
                     NTFKQGILLADAKITPYERRQLVARIEALSTEIPAQVRPLYQLWRDGQALQLQLAEER
                     QRYSKLQQSSDSELDTLRQQHHVLQQQLELTTRKLENLTDIERQLSTRKPAGNFSPDT
                     PHESEKPAPSTHEVTPDEP"
     gene            complement(59343..60770)
                     /gene="qseE"
                     /locus_tag="RN951_000870"
     CDS             complement(59343..60770)
                     /gene="qseE"
                     /locus_tag="RN951_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417051.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two component system sensor histidine kinase
                     QseE/GlrK"
                     /protein_id="HDX2525918.1"
                     /translation="MKRWPVFPRSLRQLVMLAFLLILLPLLVLAWQAWQSLNALSDQA
                     ALVNRTTLIDARRSEAMTNAALEMERSYRQYCVLDDPTLAKVYQSQRKRYSEMLDAHA
                     GELPDDKLYQALRQDLNNLAQLQCNNSGPDAAAAARLEAFASANTEMVQATRTVVFSR
                     GQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLG
                     NSVSFSGPSELRSVGQRILWLSERLSWLESQRHQFLRHLSHELKTPLASMREGTELLA
                     DQVVGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADSAVELENVELAPLVETV
                     VSAHSLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSS
                     HGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQG
                     ELYLVDESGQDVCFRIELPSSKNTK"
     gene            complement(61346..65233)
                     /gene="purL"
                     /locus_tag="RN951_000871"
                     /gene_synonym="purI"
     CDS             complement(61346..65233)
                     /gene="purL"
                     /locus_tag="RN951_000871"
                     /gene_synonym="purI"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HDX2525919.1"
                     /translation="MMEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLN
                     APLNDDEHAQLERLLKYGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQ
                     VNRLERGVAYYIEAGTLTNEQWQQVTAELHDRMMETVFFDLDDAEQLFAHHQPTPVTS
                     VDLLGQGRQALIDANLRLGLALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCR
                     HKIFNADWIIDGEQQPKSLFRMIKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHE
                     TGRYDFHQEPAHILMKVETHNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVG
                     FSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALNGYFRTY
                     EEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKGEINVGAKLVVLGGPAMNIGLGG
                     GAASSMASGQSDADLDFASVQRDNPEMERRCQEVIDRCWQLGDANPILFIHDVGAGGL
                     SNAMPELVSDGGRGGKFELRDILNDEPGMSPLEIWCNESQERYVLAVAADQLPLFDEL
                     CKRERAPYAVIGEATEELHLSLHDRHFDNQPIDLPLDVLLGKTPKMTRDVQTLKAKGD
                     ALVREGITIADAVKRVLHLPTVAEKTFLVTIGDRSVTGMVARDQMVGPWQVPVANCAV
                     TTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEALTNIAATQIGDIKRIKLSANW
                     MAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSMKTRWQEGNEEREMTSPL
                     SLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGATALAQVYRQLGDKPAD
                     VRNVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFAGHCGINADIASLGD
                     DRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVGQAVFGNRFVITANGQT
                     VFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVKLSFDINEDVA
                     APYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRTGLEDFHAL
                     VACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQMMSNLRE
                     LIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVR
                     DAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITSVTTESGRVTIMMPHPE
                     RVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG"
     gene            65491..67047
                     /gene="mltF"
                     /locus_tag="RN951_000872"
     CDS             65491..67047
                     /gene="mltF"
                     /locus_tag="RN951_000872"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417053.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltF"
                     /protein_id="HDX2525920.1"
                     /translation="MKKLKINYLFIGILALLLAVALWPSIPWFGKADNRIAAIQARGE
                     LRVSTIHTPLTYNEINGKPFGLDYELAKQFADYLGVKLKVTVRQNISQLFDDLDNGNA
                     DLLAAGLVYNSERVKNYQPGPTYYSVSQQLVYKVGQYRPRTLGNLTAEQLTVAPGHVV
                     VNDLQTLKDTKFPELSWKVDDKKGSAELMEDVIEGKLDYTIADSVAISLFQRVHPELA
                     VALDITDEQPVTWFSPLDGDNTLSAALLDFFNEMNEDGTLARIEEKYLGHGDDFDYVD
                     TRTFLRAVDAVLPQLKPLFEKYAEEIDWRLLAAIAYQESHWDAQATSPTGVRGMMMLT
                     KNTAQSLGITDRTDAEQSISGGVRYLQDMMSKVPESVPENERIWFALAAYNMGYAHML
                     DARALTAKTKGNPDSWADVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQIS
                     LVGYLQEKEKQATEAAMQLAQDYPAVSPTELGKEKFPFLSFLSQSSSNYLTHSPSLLF
                     SRKGSEEKQN"
     gene            complement(67044..67580)
                     /gene="tadA"
                     /locus_tag="RN951_000873"
     CDS             complement(67044..67580)
                     /gene="tadA"
                     /locus_tag="RN951_000873"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HDX2525921.1"
                     /translation="MRRAFITGVFFLSEVEFSHEYWMRHALTLAKRAWDEREVPVGAV
                     LVHNNRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVMQNYRLIDATLYVTLEPCVMCA
                     GAMIHSRIGRVVFGAHDAKTGAAGSLMDVLHHPGMNHRVEITEGILADECAALLSDFF
                     RMRRQEIKAQKKAQSSTD"
     gene            complement(67605..68240)
                     /gene="yfhb"
                     /locus_tag="RN951_000874"
     CDS             complement(67605..68240)
                     /gene="yfhb"
                     /locus_tag="RN951_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417055.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase C"
                     /protein_id="HDX2525922.1"
                     /translation="MATHERRVVFFDLDGTLHQQDMFGSFLRYLLRRQPLNALLVLPL
                     LPIIAIALLIKGRAARWPMSLLLWGCTFGHSEARLQTLQADFVRWFRDNVTAFPLVQE
                     RLTTYLLSSDADIWLITGSPQPLVEAVYFDTPWLPRVNLIASQIQRGYGGWVLTMRCL
                     GHEKVAQLERKIGTPLRLYSGYSDSNQDNPLLYFCQHRWRVTPRGELQQLE"
     gene            68449..69297
                     /locus_tag="RN951_000875"
     CDS             68449..69297
                     /locus_tag="RN951_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417056.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDX2525923.1"
                     /translation="MNGLLRIRQRYQGLAQSDKKLADYLLLQPDTARHLSSQQLANEA
                     GVSQSSVVKFAQKLGYKGFPALKLALSEALASQPESPSVPIHNQIRGDDPLRLVGEKL
                     IKENTAAMYATLNVNSEEKLHECVTMLRSARRIILTGIGASGLVAQNFAWKLMKIGFN
                     AAAVRDMHALLATVQASSPDDLLLAISYTGVRRELNLAADEMLRVGGKVLAITGFTPN
                     ALQQRASHCLYTIAEEQATNSASISACHAQGMLTDLLFIALIQQDLELAPERIRQSEA
                     LMKKLV"
     gene            69353..69613
                     /gene="yfhL"
                     /locus_tag="RN951_000876"
     CDS             69353..69613
                     /gene="yfhL"
                     /locus_tag="RN951_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster ferredoxin YfhL"
                     /protein_id="HDX2525924.1"
                     /translation="MALLITKKCINCDMCEPECPNEAISMGDHIYEINSDKCTECVGH
                     YETPTCQKVCPIPNTIVKDPAHVETEEQLWDKFVLMHHADKI"
BASE COUNT        16509 a        19217 c        17557 g        16338 t
ORIGIN      
        1 tatacgcaat acatttactt tcctcttttg atgatcttaa atgtcttatt tttcgtaatg
       61 tgtataacaa ggaatagtga tgaaatttaa aaaatgtctt ctgcctgtgg caatgttagc
      121 gtcattcact ctggcaggat gccagtcaaa tgctgacgat catgccgccg atgtttatca
      181 aaccgatcaa ctgaatacca aacaagaaac taaaaccgtt aatattattt ccattcttcc
      241 cgcaaaagtt gccgtagaca actcccaaaa taaacggaac gcacaagcct tcggcgcgct
      301 tattggcgca gtcgctggcg gtgttatcgg ccacaacgtc ggttctggca gcaattccgg
      361 aacgacggca ggggcagttg gcggcggagc tgtaggcgcg gcagcgggtt ctatggtgaa
      421 tgataaaacc ttagtggaag gtgtttcttt aacatataag gaaggcacca aagtgtatac
      481 ctctacccag gtgggtaaag agtgccagtt tacgacaggt ttagccgttg ttattaccac
      541 aacgtataac gaaacgcgta ttcagccaaa tactaaatgt cctgaaaaga gctaataatc
      601 aggaggagtc atgaagaaag tttttctttg cgccatcttg gcctccttaa gctatccggc
      661 tatcgcctca tcattgcagg atcaactctc tgctgtagca gaagctgaac agcaaggtaa
      721 aaatgaagag caaaggcagc atgacgaatg ggtcgcggag cgcaacaggg aaatccagca
      781 agagaagcaa cgtcgcgcaa atgcccaggc cgccgctaac aaaagagcgg caacggcagc
      841 agcaaataag aaagctcgtc aggataaact ggacgccgaa gcctctgcgg acaaaaaacg
      901 cgatcaaagt tatgaagatg agctacacag cttagagatt cagaaacaaa aactggcgct
      961 ggcaaaagaa gaagcccgcg ttaagcgaga aaacgaattt atcgatcagg aactgaagca
     1021 caaagctgcg caaaccgatg tggtgcaatc tgaagctgac gccaacagaa atatgactga
     1081 aggcggtcgc gatctgatga aaagcgtggg caaagcagaa gagaacaaat cggacagctg
     1141 gtttaattaa tcgatgttag taacttcaag cctatgattc ttgaagataa aaaaccctct
     1201 gtagtaacag agggttttgt tcattcatag tgcagggatt aaaatcattc ccactcaatg
     1261 gtagctggcg gcttgccgct gatgtcatac accacgcggg aaataccgtt cacttcattg
     1321 ataatgcggt tggaaacgcg accgaggaaa tcgtacggca gatgcgccca gtgtgcggtc
     1381 ataaagtcga tggtttcgac agcacgcaga gagacaaccc agtcatactt acgaccatcg
     1441 cccattacgc caacggaacg taccggcagg aacacagtga acgcctggct gactttgtcg
     1501 tacaggtccg ctttacgcag ttcttcaatg aagatggcgt cagcacggcg cagcaggtca
     1561 cagtactctt tcttcacttc acccagcaca cgaacgccaa ggcctggtcc cgggaacggg
     1621 tgacggtaca gcatgtcgta cggcaggccc agctccagac caatcttacg cacttcgtct
     1681 ttgaacagct ctttcagcgg ttcaaccagg cccatcttca tctctttcgg caggccgccc
     1741 acgttgtggt gagatttgat gacgtgtgct ttaccggttg cagaagccgc agattcgata
     1801 acgtcagggt agatggtgcc ctgcgccagc cacttcacgt cttccagttt cagcgcttct
     1861 tcatcgaata cttcaacgaa aacgcgcccg atgattttac gttttgcttc cggatcgttt
     1921 tcgccagcca gcgctgacag gaagcgatct tctgccggta cgtgaacaat gttaagacca
     1981 aagtgatcgc caaacatatc cagaacctgc tctgcttcgt tgagacgcag caggccgttg
     2041 tcgacgaata cgcaagtcag gtttttaccg atagcgcggt gcagcagcat tgcggttacg
     2101 gaggaatcca caccaccaga gaggccgagg atgactttat cgtcgccgac ctgctcgcgg
     2161 atgcgagcta cagcatcgtc gataattttc gctggcgtcc acagggcttc acactggcag
     2221 atatcacgca caaaacgctc cagcatgcgc ataccctggc gggtgtgagt cacttccggg
     2281 tggaactgta cgccatagaa gcgtttttct tcgttagcca taatggcaaa cgggcagctt
     2341 tcggtgctgg ctacggtgac gaagtcggac gggatagcgg taactttatc gccgtggctc
     2401 atccagacat cgagcagcgg tttaccgtct gcggtcagcg catcttcgat accgcgaacc
     2461 agtgcgctgt cgtttacgac ttcaacctgc gcgtagccaa attcacgttc gttagaggct
     2521 tcaacgtgac cgcccaactg cattgccatg gtctgcatgc catagcaaac gccgaatacc
     2581 ggtacgcctg cttcaaagac atactgcggc gcacgcgggc tgttttcttc ggtggtgctt
     2641 tccgggccgc cggaaagaat aatgccgctt ggattgaagt cacgaatttg tgcttctgtc
     2701 acatcccacg cccacagttc gcagtaaaca cccagctcac gcacgcggcg cgcaaccagt
     2761 tgagtgtact gagaaccgaa gtccagaatg aggatgcgat gcttatgaat gttttccgtc
     2821 attgacgctt attccgaggc aagtgaaaca gataatataa atcgcccgac atgaagtcgg
     2881 gcgaagagaa tcaggagccc agacggtagt tcggggactc tttagtaatg gtcacgtcgt
     2941 gaacgtggct ttcctgaatg cccgcaccgc tgatacgtac aaactccgct ttagtacgca
     3001 gttcgtcgat agtaccacag ccggtcagac ccatacagga gcgcaggccg cccatctgct
     3061 ggtgaatgat ctctttcagg cgacctttat aagctacgcg accttcgata ccttccggca
     3121 ccagtttgtc ggcagcgtta tcgctctgga aataacggtc agaggaacct ttggacatcg
     3181 cgcccaggga acccatacca cggtaagatt tgtaagaacg gccctggtag agttcgattt
     3241 cacccggaga ttcttcagta cccgccagca tggaacctac catcaccgcg cttgcgccag
     3301 cggcgatagc tttggcgatg tcgccggaga agcgaatacc accatctgcg ataaccggaa
     3361 taccggtgcc ttccagggct tcaactgcgt cagcaacggc agtgatctgc ggaacaccta
     3421 cgccagtaac gatacgagtc gtacagatag aaccagggcc gataccgact ttaaccgcgc
     3481 tgcaaccagc ttctgccaaa gcgcgtgcac ctgcagctgt tgccacgttg ccgccgatga
     3541 tttgcagatc cggatattta gcacgggttt cacggatacg ctgcaaaacg ccttctgagt
     3601 gaccgtggga ggagtcgatc agcagaacgt caacgccagc ggcaaccagc gcgtcaacac
     3661 gctcttcgtt acccgcacct gcgccaactg cagcaccaac acgcagacgg ccttgctcgt
     3721 ctttacaggc gttcggttta cgttccgctt tctggaagtc tttcacggtg atcatgccga
     3781 tcaggtggaa ttcgtcatca accaccagcg ctttttcaac gcgtttttcg tgcatttttg
     3841 ccagcaccac ttcacgggct tcaccttcac gcacggtgac cagacgctct ttcggcgtca
     3901 tgtaaacgct aaccggctgg ttcaggtcgg taacaaaacg cacgtcacga ccggtgataa
     3961 tacccaccag ttcgttttct tcggtaacga ccggatagcc cgcaaaaccg ttacgctcag
     4021 tcagttcttt cacttcgcgc agcgtcgtgg ttggcagaac agtctgcgga tcagtcacca
     4081 caccagattc gtgttttttc acacggcgaa cttcttctgc ctggcgttca atggacatgt
     4141 ttttgtggat aaagccgata ccgccttcct gagccagagc aatagccagg cgcgcttccg
     4201 ttacggtatc cattgctgcg gaaagcatag ggatattcag acgaatagtt ttcgtcagct
     4261 gggtgctgag gtcagcagta ttcggcagaa cggtagaatg agcaggaacg aggagaacgt
     4321 cgtcaaacgt cagagcttct ttagcgatac gtagcatggg caatatctcg accagagtgg
     4381 ttaataaata ttgccgcggc attatacaga gcgtaaccga ttgcatctac ccctttttgc
     4441 aaaaaatgct tgctatcccc gaagggcggg ttactatcga ctgaataacc tgctgattta
     4501 gaatttgatc tcgctcacat gttaccttct caatcccctg caatttttac cgttagtcgc
     4561 ctgaatcaaa cggttcgtct gctgcttgag catgagatgg gacaggtttg gatcagcggc
     4621 gaaatctcta atttcacaca accggcttcc ggtcactggt actttacact caaagacgac
     4681 accgcccagg tacgctgcgc gatgttccgc aacagcaacc gccgggtgac cttccgtcca
     4741 cagcatggac aacaagtttt agttcgcgcc aatattacgc tctacgagcc gcgcggtgac
     4801 taccagataa tcgttgagag tatgcagccg gccggtgaag ggctgctgca acagaagtac
     4861 gaacagctca aagcgaagtt gcaggctgaa ggtttgttcg atcagcaata caaaaaacca
     4921 cttccctccc ctgcgcattg cgttggtgtg atcacctcaa aaaccggtgc tgcgctacat
     4981 gatattttgc atgtgttaaa acgtcgcgat ccttctctac cggtgatcat ctaccccacc
     5041 gccgttcagg gcgatgacgc accggggcaa attgttcgcg ccattgaact ggcgaatcag
     5101 cgcaatgagt gcgacgtgtt gatcgttggg cgcggcggcg gttcgctgga agatttatgg
     5161 agttttaacg acgaacgcgt agcgcgggcg atttttgcca gccgcattcc ggtcgtcagc
     5221 gccgtcgggc atgagacgga tgtgaccatt gccgattttg ttgccgatct gcgtgcgcca
     5281 acgccgtctg ccgccgctga agtagtgagc cgtaatcagc aagagttact gcgccaggtg
     5341 caatcgaccc gtcaacggct ggagatggcg atggattatt atctcgccaa ccgcacgcgt
     5401 cgctttacgc agatccatca ccgattacag caacagcatc cgcagctccg gctggcacgc
     5461 cagcaaacca tgcttgagcg cctgcaaaag cggatgagct ttgcgctgga aaatcaactt
     5521 aagcgtaccg ggcaacagca gcagcggtta acacagcggc tgaatcagca aaatccacag
     5581 ccgaagattc atcgcgcgca aacgcgcatt cagcaactgg aatatcgttt agcagaaacc
     5641 ctgcgcgtac agcttagcgc cacgcgtgaa cgtttcggta atgcagtaac gcacctcgaa
     5701 gccgtaagcc cactgtcaac gctggcgcgt ggatacagcg ttactactgc tactgacggc
     5761 aatgtactga aaaaagtgaa gcaagttaaa gcgggtgaaa tgctaaccac acgtctggaa
     5821 gacggctgga tagaaagtga agttaaaaac atccagccag taaaaaaatc gcgtaaaaag
     5881 gtgcattaag ccagcacgaa ttcaacgcgt tttttcgata tcaagccatg cccgtgctga
     5941 cagaagtaat ctactgcacc gcaggctttt aacacctgca acggttgatg gcagtctgga
     6001 caaagagctt tcatttcaat aatttccccg caggatgggc aacgcgcatg gccgttatcc
     6061 tgatcaagca catgctgaca ttgtggacaa tgcagttcca tatgaattcc tccggtagcc
     6121 atccctctac attcatagag ggaatggcag ataaaatact tacggataat tatttatttt
     6181 tcttgatgtg cttcatcaga cgcttacgtt tacgcatctg ggttggcgtc agggtgttac
     6241 gcttgttcgc atacgggttt tccccttctt tgaactgaat acgaatcggc gatcccatta
     6301 cgtccagcga tttgcggaag tagttcatca agtagcgctt gtaggaatca ggcaggtctt
     6361 tcacctgatt accgtgaatc accacaatcg gcgggttata accaccagcg tgggcatatt
     6421 tcagcttcac acgacgaccg cgtaccagcg gcggttggtg atcttcaaca gccatcgtca
     6481 tgatgcgcgt cagcatagag gtccccacac gacgggtgga gctgtcatac gcttcacgta
     6541 ctgattcaaa caagttacca acaccactgc cgtgcaaggc agagataaag tgcacacgag
     6601 caaaatcgat aaagcccaga cggaagtcca gcgtttcttt cacctgctct ttcacttcct
     6661 ggctcaggcc atcccactta ttcaccacaa tgacaagtga gcgcccacta ttgagaataa
     6721 agcccagcag cgagagatcc tgatcggaaa taccttcgcg cgcatcaatc actaacatca
     6781 ccacgttggc atcttcaatg gcctgcaacg ttttgattac ggagaatttc tctacagcat
     6841 cggtgatttt gccgcgttta cgtacgccag cggtgtcaat gagcacatac tcacgtccat
     6901 cgcgttccat tggaatgtag atactgtcac gcgtcgtgcc aggcatgtca taaacaacaa
     6961 cgcgctcttc accaagaata cggttagtga gtgtagactt acctacgttc ggacgaccca
     7021 caatcgccag tttgatcggc agactttgcg ggtcgaagtc gtcttcctct tcttcttcgc
     7081 cgttctcttc cgcttcaaat tgcgcccagt attcagcgtc ttcgtcgact tcctcttgcg
     7141 gtgcgagatc ttccatccac ggcagcagca catgctccag cagacttaat acgccacgac
     7201 cgtgagacgc ggcgatcggg tagatttcac ctaaaccaag cgagtagaaa tcaaccactg
     7261 cctgatcggg atccagaccg tcagttttgt ttgccaccag gaaggtcggt ttttcacggg
     7321 agcgcagatg tttggcaatc gcttcatctg ccggcatcag gcccgcgcgc gcatccacca
     7381 taaacagtac gacgtccgct tcttcaatcg ccagcagcga ctgttccgcc atgcgggttt
     7441 ctacaccgtc ttctgtgcca tcaatcccgc cggtatcaat acagataaac tcacggcctt
     7501 caatttccgc acgaccgtac ttacggtcac gagtcagacc cgggaaatcc gcaaccagcg
     7561 catctcgggt gcgagttaga cggttaaata acgtggattt tcctacgtta gggcgcccga
     7621 caagcgcgac cacaggtacc atgtttaaag cctcattttt ataaatcatc agacaacgca
     7681 cgctatattc gcgtcgttgt taaaaacagg aaaacggccc ctgtccagga gccgttttca
     7741 aagtgaacga cagagacgat taacgtgtaa tagagtacac ggttccgtct tttgcctgga
     7801 tcagcagttt gccgtcagcg gcaaccggtt cagtctggaa accggaacta tcaacttttt
     7861 gctgggcaac gaaacgacca tcttcgacgt taatccagtg cagataacct tcactgtcac
     7921 cgaccaccag gttgccatta tacagcaccg gagaagtcag caggcgatgc agcagatcgc
     7981 tttgtgccca cagcgtaacg ccgccatcaa tggtcaacgc catcacccgg tcattttgat
     8041 cgaccagata gatgcgattg ccgtcgacga tgaaatcatt caccgaaccc agttcgcgtt
     8101 tccacataat ctgaccactg cgcagatcaa gcgccgtcag gttaccatta taggccagcg
     8161 cgaaaacaac gccgttaaca acgacgggag tcgtgtcaac atcgctcaga cggtcaattt
     8221 cggtagaacc ggtcgcctgg gaaatacgct gctgccaaat catctggccc tgttccatca
     8281 gcactgcgct gacgcgacca ttatcgcccc ccacgacggc cgcaccaaaa gccgttgccg
     8341 gcgcagactc gccacgcaaa gagagcgaag gcatatcgag gttaactgtc catttgacag
     8401 cgccgtcagc ttcgttcagc gcttgtaact gaccgttact ggtgtggatt aacaccagac
     8461 cgtcgctgac caccgggcgc gaaagtgctt cacccgcgac tttagtttgc catgccacag
     8521 taccatcgct ggtattcagc gcgtaaacct gcgccttttc gctgccaatg tagacatgcc
     8581 caccagacac ggtcacaccg ccagaaagta atgcaggctc tttagagaac cagccatctt
     8641 tctcggccag gctgacagac cagatttctt tgccatcatc cgcattcagc gcttttacca
     8701 aaccagcgcg gtccgctgca tagacaacgt tgtccgccag tgccggatga agattggaat
     8761 agaagttgcc aatgccgcta ccaacggaag tactccacgc cgtggtcggc gtaaactggt
     8821 tttcaacggt tggcaatggg gacatcttta ccacatcttc ttcgctgtta aacagcgaac
     8881 agccgcttaa aagggtaacg gaaagcagtc ctggcagcag taatttacgc aattgcatcg
     8941 ggtccctctc agatggacaa attattaatt ttcatctgca tcatttcgct cagtgccgga
     9001 gtaacatcgc ttttcacgcc tgcttcccat gcactacgcg caccttgctt atcacctttg
     9061 ctcagcaatg cttcaccacg caggtcggca acaatggcag cccacccttc acctttgatg
     9121 gtatcaaggg ttttcagcgc ggcatcagcc tgcttgagct gtacctgaac gcgagcaaga
     9181 cgcagattta tcacggcttt gagattttca tcgctcgtgt ctgccagccc ctgttgtaac
     9241 tgggcggcag ctttctctag ttcatttttg tcaacaaatt gctgcgcaag ttccaaagaa
     9301 gccagcgcac cataagtatt tttattttca gcagcaaatt tttccgccgc cgggatgcta
     9361 tccggtttgc cttcgctcac tgcggtaacc gcattttgat aggcaagaga agcggagcgt
     9421 gcagaatcaa cctgatggct gttccagtag cgccagccaa tcagtgcgcc aacgcccaaa
     9481 atcaccccaa cagccagtgc tttgccattt tcagcaaaaa agcgtttaac cgcttctacc
     9541 tggtcgtttt cgttctcgta aatttccacg ctgtccttct ccttccttaa cccagtaacg
     9601 tgcgcaaatg cgcggctacg ctatcctgcg caactgccgt ttgctcacca gagcgcaaat
     9661 ccttcactac tgctgtgccg ttagccactt cagactcacc cagcaccaca gcaacgcggg
     9721 caccccattt atcagcacgg gcaaactgtt tcttaaagtt gccgccgccg tggttggtca
     9781 tcaatttcac gcccggtaat tcatcacgca gacgctcagc taatgccata gccgcagatt
     9841 gtgtatcagc acctgaagcc accaggtata tatcgacaac aggatcggct ttaaattccg
     9901 gattaacggc ctgtactaac aatacaagac gttcgaggcc catcgcaaaa ccgacagccg
     9961 gtgttgcacg accgcccagt tgttccacaa gaccgtcata acgaccgcct gcacacacgg
    10021 tgccctggga gccgagactg ttagtcaccc actcgaaaac ggtacggtta tagtaatcca
    10081 gaccacgcac cagacgctgg tttacggtgt aagcgatccc cgcgctctca agcagtttgc
    10141 acagaccggc aaaatgctca cgagattcct cgtccagata atcacctaat gccggagcgt
    10201 cgttgagaag cgcctgcact tccggatttt ttgaatccag cacgcgcagc gggttagtgt
    10261 acatgcggcg tttgcagtct tcgtccagct tttctttatg ctgctcaagg aatgccacca
    10321 gcgcatcgcg gtaattggcg cgtgcttcca gcgaaccgat agaattcagc tcaagagtta
    10381 cgtgttcgga aatacccagc gcgcgccacc agcgggcggt gagcataatc agttcagcgt
    10441 cgatatccgg accttgcaga ccgaaaactt cgcagcccaa ctgatggaac tgacgataac
    10501 gccctttctg cggacgctcg tgacggaaca tcggcccgat ataccacaga cgctgttcct
    10561 gattgtacag aagaccatgc tcgatgccgg cgcgtacaca gcccgccgtc ccttcagggc
    10621 gcagagtcag gctgtcgcca ttgcgatcct caaaggtgta catctctttt tcaaccacgt
    10681 cggtgacttc accaatcgca cgtttgaata gcggggtctg ctctacaatc ggcaagcgga
    10741 tttcactgta accgtagctg ccgagcacgt ttttcagtgt gccttcaatg cgctgccaga
    10801 tggccgtttc gccaggcagg taatcgttca tgccgcgaat ggcttgaatg ttttttgcca
    10861 cgtttattct ctttctgaat ataaaaatga accctcaacg cttccctcaa tgtttcggga
    10921 gctatgcggg ttcaatcata cacgggaagc gaggcgcttc ccatcacgtt attatttttc
    10981 aacctgctga acgtcaattc gacgcgcttc gtccagctga ctggctttcg cacgaatgcg
    11041 tgcttccagc tggtcgatca tatcgttgtt gtccagacgg tctttgcgca cgccatcttc
    11101 atagaggccg cttttcttgt tgccgccggt gacgccgagt gtagaaacca gcgcctcacc
    11161 tgggccattc accacgcagc cgataatcga aacgtccatc ggagtgatga tatcttccag
    11221 gcgttgctcc agcgcgttaa ccgtaccgat aacatcaaat tcctgacgcg aacaggtcgg
    11281 gcaggcgatg aagttgatcc cgcgcgaacg gatacgcagc gatttcaaaa tatcgaaacc
    11341 gactttgatc tcttcgaccg gatcggccgc cagtgatacg cgcagcgtgt cgccgatgcc
    11401 ttcagacagc agcagaccta aaccaatggc ggattttact gccccgctgc gtgcaccacc
    11461 ggcttcggtg atccccagat gcagcggctg atcgatctgt tttgccagca aacgataaga
    11521 ctcaacagcg aggaagacgt cagacgcttt cacgctgact ttgaactgat cgaagttcag
    11581 gcgatcgaga tgatcaacat ggcgcatggc ggattccagc aacgcctgcg gcgtcggttc
    11641 gccatacttt tcttgcagat ctttttccag cgatccggcg ttaacgccaa tacggatcgg
    11701 aatgttttta tcgcgcgcac agtcaaccac catgcgaata cgctcttcat taccgatatt
    11761 gccagggtta atacgcagac aatcgacgcc gtattccgct actttcagtg caatgcgata
    11821 gtcgaagtgg atgtcagcca ccagcggcac gttaacctgc tgtttgatga gtttgaacgc
    11881 ttctgccgcg tccatcgtcg gtacggagac acggacgata tcagcgccaa cgcgttccag
    11941 cgccttgatt tgattgaccg ttgcttcgac gtctgtcgta cgcgtattgg tcatggactg
    12001 tacggcgatg ggagcaccat cgccaatcgg cacattccca acgtaaatac gtgttgattt
    12061 tctacgttga attggagcct ggttatgcat gaaaaatctc ccgcgttacc cgtctgttac
    12121 tgcgccggtg attgttcggc attgagggtc agacgcgcaa cctggttagt tctgataaaa
    12181 cgactcagat cgacaggttt cccttgatac tggatctgta ctgcggctgg cgcaccaatt
    12241 ttcagtttgt atggtgcctg gccggttaag ttcaaattac cgtctttacg ctgcataccg
    12301 ctaaacaatt ttttaccggt agcatcagta acctccagcc agcaatcggc agtaaagttc
    12361 atcaccagcg cattcggatc agccgccggc gtagtcacgc ctgcctgatc ggttggcaac
    12421 ggcgcagcgc catctggcgt tgttgttgcc gttggtgccg gggtcgcggc ggtatcaaca
    12481 tttgcctgcg aaggcgaaac aaccgcattc tgttgcggat caacagctgg tgctggcgca
    12541 gttacggcag gtgtttgcgt gttggttgcg gtagtatcca cagacgctgg cggcgtggac
    12601 gttgtagccg ggtctgtagt tgtcgacgta tttaacggaa cactctgccc ctgctcgcta
    12661 ttactgctca gttccgccga agattgatcg gccatagtgg tgatctcttc ctgctgagct
    12721 ttgtggtctt gccaccacca ggcaccgctc aggccgataa ccacaaacaa caccagccag
    12781 gtgaaggtca tcagccagcc gtcacgtttt ttgcggcgtt taccgaggga aaaactctgc
    12841 ataggcgcaa cttttgcagc ccgtagtgga gcctgctttt ccagccctgg cagcagttct
    12901 tcttctggaa tatgtaccag acgcgcataa gagcggatat atccgcgcag gaatgttgaa
    12961 gcaagatcgg cgggtgcctt atcttcttca atgtcgcgta ccgtggaaac cttcaggcaa
    13021 agtcgctcgg caacggcctg ctgactaagt cctagttgtt cgcgagcatt acgcaggcga
    13081 gcgccggtag taagtgcttc attttggtcg tgcgtggctt cagtattcat tcgctgcagg
    13141 tacgtttaaa tgagaattga gatgccggtg aaccatcatg ctcacccaca ccgcgaaaca
    13201 tccgttaagt taaccgttat catacagtat aagaccgtct gtgtgctcgt gacaaagccc
    13261 acattcacta aggctaactt actgttgcat cgttacatac tgccttaaag tcagcaaaaa
    13321 cgcaccgtta atattgacca gacaattgca acttaatact tcattcataa aagattacgc
    13381 cacggtacat aaagtaaccg tggcgtaatg gctatcagac cgctttaatg tcgatggctt
    13441 caccctgcat ccgtttacgc agggtacgtt tcgtacggtc gataacatcg cccgccaact
    13501 gaccacaggc agcatcgata tcatcaccac gggttttacg cacaatagtg gtgaaaccgt
    13561 agctcatcag cacttttgag aaacggtcga tacggctgtt cgagctgcgt ccatacggcg
    13621 cgcccgggaa ggggttccac gggatcaggt tgatcttaca cggcgtatct ttcagcagtt
    13681 ccgccagttg gtgcgcgtgt tcagtgccgt cgttaacgtg gtcaagcatc acatactcaa
    13741 tagtgacacg gccctgattg gcgttggatt tctccagata acggcgcacc gcagcaagga
    13801 acgtttcgat attgtacttt ttgttgatcg gcacaatttc gtcacgaatt tcgtcgttcg
    13861 gcgcgtgcag ggaaattgcc agtgcaacgt cgatcatatc gcccagttta tccagcgccg
    13921 gaactacacc ggaagtagaa agcgtgacgc gacgtttaga caggccaaaa ccgaaatcat
    13981 caagcatgat ttccatcgcc ggaacgacgt tgttcaggtt gagcagcggc tcgcccatgc
    14041 ccatcatcac tacgttagtg attgggcgct gaccggtgac ttttgctgcg ccgacgattt
    14101 tcgccgcacg ccacacctgg ccaataattt ccgatacccg caggttgcgg ttaaagccct
    14161 gctgggcggt ggaacagaat ttacactcca gcgcacaccc cacctgcgaa gagacgcaga
    14221 gcgtggcacg gtcgtcttcc gggatataca ccgtttcgac gcgctgatcg ccaacggcga
    14281 tcgcccattt aatggtgccg tcggatgaac gctgttcttc aaccacttcc ggtgcgcgga
    14341 tctccgccac ctctttcagt ttgccgcgca acactttgtt gatgtcggtc atctcatcaa
    14401 agttgtcgca gcaatagtga tacatccact tcatcacctg atcggcgcgg aagggttttt
    14461 cacctaaatc tttaaaaaac tcccgcatct gctgacggtt gagatccagc aggttgattt
    14521 ttccatcttt cgtggtgacg ttttcaggtg tgactaattg ttcagacata tgctattccg
    14581 gcctcgttat tacacgttat ggcccctgga gggttgaaaa aagaaacgcc ccggtgagcg
    14641 gctgctcgtc cgggggcgct gcattgtaca aattctggcg cacggatgcc acgtttgcac
    14701 gcggcattta cgaaattatt aacgggtgcg cgggcacact tcgccttcgc caaagaaata
    14761 agcgatttcg cgagcggcag attcgacgga atcagaaccg tgggtaccgt tttcggtcag
    14821 gctgtcagcg taatcagcgc gcagagtacc agccagtgcg tttgccggat tggtcgcgcc
    14881 cagcagatcg cggtgacgct gaacggcgtt ttcaccttcc agcacggaaa ccacgatcgg
    14941 gccagaggtc atgaattcaa ccagaccatc aaagaacggt tttccatcgt gttcagcata
    15001 aaagccacgt gcctgttcaa cggtcaggtg cagcattttg gtgccgacaa ttttgaaccc
    15061 tgcagcttca aagcgcgcaa agatattacc aatgacgttt tttgctaccg cgttcggttt
    15121 gatgatggaa aaagtacgtt caatagccat ttttacctct gtaaattgtt ctgttgttgt
    15181 ctgtaccagc gtacgagatg gcgcggatta taatgagcaa cagggccgtt gactattgat
    15241 gaaggtaaca tttttttaaa ataaaatgag ttttagcaac aatcaggggc aaaacagact
    15301 attgcatgac aaatttcact gtcgcgattt gccccacatc atccatcacc agcaattgat
    15361 aatcaccttt atccgtcaaa tgcagggtca cgttgcgccc gcgttcagtt aacggttcgc
    15421 cattcagaaa ccaccagcgt tcacctgccc ctccacttga ttgcaacggc aaagtcgctt
    15481 ccgctgcgcc cggtaaacgt ttaataatcg cgccatcgcg aacgcctgtc agctgcagag
    15541 ggagcttggc atcgtgaccg tatggcgggc aaattgtcga ggccggtggt aagcgcacag
    15601 cgcgacgttc tgatgcgggc agccagggtt ccagcggtag cggccagaca tttatcattt
    15661 cttgtcgcgc ttgcgggcaa tcagcggcaa cacgtttgcc attttcatcc agccagatgg
    15721 ggaaacgaat gccattaatg ccttcctgct ccggcagtaa tagagttggc ggctgactcc
    15781 cgtccagcag ccaggttgcc aggcggcggc gacagttacc gtcaccttcc ggcaaagact
    15841 gtccgcccgg ccagcagata acgccacgag tgactgagtt cgggcgcggg tcttccggca
    15901 gattcgcact gcgcgacagt aagatattat tgacctgatt caacaatggt acggcactgg
    15961 caaagccaaa ctgaccaaca acgggcgtgc cgtccggtct gccagtccag atcccaatga
    16021 catagcgagc gttaacccca atcgcccagg cgtcacgata gccatagctg gtgcccgttt
    16081 tccatgccag tggggcgacg cgcggcaagg cactatccgg caagggtttc gcttcatcag
    16141 ccataatccg gcgaatgatc cacgccgccc ccgacgacat taaaggccgt tcaagcagcg
    16201 gatcgtcagg ctgtaagcgc aatttgcctg ccttgccgtg gcgagcaaac gcggtatacg
    16261 ctgccgccat atcttccagt tttgcaccag cgccgccgag aatgagtgaa agattcggcg
    16321 cagcaccgtt gggcaaatat aacggcaatc caacattgcg taactttgcc gcaaaccgtt
    16381 tcggtccata ggcttccagc acctgcacag caggtaagtt cagcgagcgc accagcgcct
    16441 cgctcatgct gatcgggcca tgaaaaccgc tatcaaagtt acctggtcga taatcaccgg
    16501 tgcgccgggg gacgtcttgc agcagtgatg ccgggtggat caagccttca tccagcgcca
    16561 gaccataaac aaacggtttg agcaccgatc ctggcgatcg gatcgcattg accatatcaa
    16621 catgaccaaa gcgtgaatca tcgttgagat caaccgatcc cacccagccg cgaacacgca
    16681 tatcgatatg atcaaccacg atcatcgcca gtgagctgcg cggtggcaac cgccctttcc
    16741 agttttgcgc cagttcttcc agacgtcgtt gaagaccggc atccagcgta gtaacgattt
    16801 tgtcgctttt gcttttaccg agcatcatgc gcgaaaacag cggtgccagt tgcggcattt
    16861 gtcggggtgc cagccagatg ggttcttccc ttgactcttt tacctgctca cgggaccacg
    16921 caccttgcac ggccatccgt tcgagcactt tattacgcgc ggcttcggca cgctccggcc
    16981 aacgatccgg gcgaagacgg ctgggcgctt gcggcaaaac cgccagcatt gccgcctcgg
    17041 aatagcttaa attcgcaggc gactttccga gataagccca acttgccgca ccgatcccct
    17101 gcaacgtacc gccaaacgga gcgcggttaa gatacaaggt cagaatttca cgcttagaca
    17161 gatgccattc cagttgcaac gcgcgccaga gctggcgaat tttgccgcca aatgttttgg
    17221 ggtgaggatc aagcagacga gcaacctgca tagtgagcgt gctgccaccg gaaataaccc
    17281 gtcccgaagt gagatcttgc catgctgcgc gcgccaccga gaatggattc atccccggat
    17341 gcttccagaa ccagcgatct tcataattga tcagcgcttc aaggtaacgt ggagaaacat
    17401 cttcgattgt taccggataa cgccagatgc cgtcagcatc ggcgaagcgc catagcggcg
    17461 taccatcctg cgccacgacc actcgtgcgg gattgacttc atgcagcggt agaggccaga
    17521 gtttatctgc tccccacgct gcaagaaaaa ggagaaatgg cgcagctgcc agcgttatcc
    17581 agcagccgcg tttggttaac aagcgaggca tttacggtcg gacaatcagc agatcttcag
    17641 ccgcgccggt cgcccgccat tggggaacat acattgattc caccatcggt tgcggtacct
    17701 gatacgttcc cggcgtcacc gcccgcgcca gatacaccag cgttaccggt tggtattcat
    17761 caacggcaac cgccgccaca aagcgatcgt cacggaactc aatgtgctta atactcgcct
    17821 gctgcatctg gttcagtaag ttctgcactt cgccaccact ttgctccagg ctggcgctac
    17881 cgttcgccag attctggttt tccagttcca gacccgcagg cagcagatcc acgaccaacg
    17941 catccggcac gctgttactg gcttttacct gcaaccacac cagcaccaga tcgccgctac
    18001 gtaacgagtc cagcgatttg ctcttaccat cagtaccaag aatatgacgc tcgatttgca
    18061 gcacatcgtt cgccggtaaa ggtgcggatt gcggataacc gctggcatcc acacgcagcc
    18121 ataacggctg atcgccactg tttctcacct gcaaggtggc aagttgatcg ctattcagat
    18181 tgctgtttag cgttttctcg cctgtcagcg gctcagctga gaaagaggtt tgcgcctgcc
    18241 atttacccgg taaatcctga atcgtacggg cagccaggaa caacgcgtta ctttcctgcg
    18301 tcgatagcca gcgttcacca aacgcctgct gcgaaagtgt gttcagcaaa gtgtactgct
    18361 catcgggtag cagtttattt tcttccagca aggagagcat taacgcgttg tcgcgcagtg
    18421 gactaccgta atcacccagc catatccgct catcactatt tctcggcgtt ttcagcgcca
    18481 gcacaatcgc ttcttcacca cgcgttgcat cacccatggt tttcagcgca acgccaagtt
    18541 gcagcagcgg taaaccagaa gcggcatctg cacgatgctc ccagatttca cgcagcgcac
    18601 ccagtggtgc tttttgctga cgggccagca ccagcgcagc gtaagactga acggcgaatt
    18661 tactggcttt gagattatcc gcgtacggga tcgacatcat gcccggatct tgtaaatagc
    18721 gcagcagacg ctcattaccc cggttaatgg cgtctgtcgg cacgctgtaa ccctgttcgc
    18781 ctgcgcggac caggaaatcc atcacgtaag ccgtcagcca gtactcttcg tcaccgtttt
    18841 tatcccacag cgcaaagccg ccgttatcac gttgcatttg cagcaaacgg gaaatgccga
    18901 tatcgaccga tgcacggcgt ttctcatcac tgtcgccttt gatgcccaac gcctgcagtt
    18961 gggctgcgtt ggtataaagt gacgggaaca ggccgctggc ggtttgctca agacagccgt
    19021 acggatacgc ttttaactct ttgatataac gtgcaatgtt cagcggtggt ttgccgctca
    19081 acaacaattg cccttccagc gtaacaggcg agaagttttg caatccatcc gccggaatcg
    19141 cccatgtctc accaggctgt aacgccgtac cgtaattaac cgtttgtgcc gggaacgccg
    19201 gacggacgcc gattttccac tgcttatgct gatcggcaac ggtttcaccc ggtaacgcta
    19261 acccgctaat ggtggcctga atttctccat cgccataacc cggcaatgct cgcaccggga
    19321 taaacagcgt agtacgcaca cctggcgcta attcaacggc tgcgggtgaa tcgctgacca
    19381 gttcaagcaa accactggcg gtcagggcaa cgttcagttt ttgcggttta tcggtaagat
    19441 tagtgatatc cagcgtcaga cgcgaggtat cgccactcgc cataaagcgc ggcatgttca
    19501 gttcagcaat caccggtgcg gcaactatca ctttgctttc gttgctaccg aagtcatctg
    19561 ccgtccaggc ttgcgccatg acgcgtaatt caccgttaaa atcgccaatc ggcagtgtaa
    19621 ccgagccttc gccctgttcg ttgagcgtta ccggcagcgc ctgctgcgcg acaatattga
    19681 cgtgattgac cggcggttta ccaccacgtt tcagctcatc accatcgcca ccgaaacgca
    19741 gagctgccag acgcccctga ccttcaataa cctgaccgta aatatcgtaa atgtctgcgc
    19801 catagcgttt ctgaccaaag aacgcctgcc acggatctgg cgtgacgtag tcagtaatat
    19861 tcagcacacc actatcaacg gcagacacca gcacattcac ctgtttaggc ttctcgccat
    19921 ttttagtgct ggctttaatt ttcacggtta atggttgatt cggccgcatt tttgctggtg
    19981 tttccagcgc cagatcgagg cgacggtttt catcgccaag cggcagatgc aacaccccaa
    20041 ctgcgcgttt tggcgtcgcg gagcgagatt tatcgccagg acgtactacc agcgtactta
    20101 aatacagatc atgacgattc caggttttat cgaccggaat cgtcagatcc agcccttgag
    20161 ccggaacatc aatctcttgc caccacaacg gcccttcact ggactcgacc atcgcataac
    20221 ctttacccgc cgttggcgcg gcaatatgca acttaatggt atcgccaggg cgataactgg
    20281 ctttatccag tttcagcgtg acacggtcgg gtcgcacggc accgctcccg tcgctgttgt
    20341 cctgccagct atagccagcc cagaaacgca cgctactgac cgcttcattc ggcgctttga
    20401 cttccagacg ataagcgccc cactctaccg gaaaactgac cttgccggtt tcgtccgctt
    20461 tcagatccag agtttgttca ttttcgatca gatctttttg atcaaactgt gactgccagc
    20521 cttcatcttc tgaccagttc cagtagtaat cgcggcgttc gcgaatcagg cgcacctgca
    20581 agcccgacac ggcttttttc acgccttgcg catcgctata aacgatgtca aaagcggcgt
    20641 tactgccttc atcaacaatg ggctgtttca ccgtgctgtc agtacgataa tcgtaaaccg
    20701 atttcgaggc gaactgcgga cggatccccg gcaatgcatc ggcaggccag atagcctgct
    20761 cagcgcggcg cgtcaccggg cgaccgcccg attccagcaa actaccctgg aaaataacct
    20821 gtaatgggga atgcgtttcc ttccactggc tttctgtaga aacttcgccg cgccctttat
    20881 catccagcgt caactgaact tcatccagcg tgcgggaaag attttcggca gctatatcgc
    20941 cgaattcaaa accaggtaag gctgacacag cttcacgcag tgggcgcagg aaaagttgcc
    21001 cttgcaaagt attaccatta gcaggtgcac catacaggta gtaccccacc acggagaatt
    21061 tcacttcatc tttcggcgtt agcggggttt tctcaccggt cagattcagc gccatgcgct
    21121 ctggcataaa atcttcgacg tggaaatccc acatccgata ctggttatcg cccgtgttag
    21181 cgcgaatatg ccacataccg gttgccgcat tgctatcgag tggccaggta aagtggtaga
    21241 ggccattttc cggctgacta acgacgctcc tgagtacctg cccatcgggt ttaatcacgt
    21301 ctaacttgat gggttgattg ggcaacgctt taccgtctgc atcacgcagc aaaccattga
    21361 ggattaccgt ttcacccggg cgataaagat cgcgtgggcc aaacatgaaa aactgtttgc
    21421 tatagcctgg cgcgccagca atgttaaatt ctgctaagtc cagcgccgga agttttaaat
    21481 cgagtagcgt tgtctgaccg tctttacgcg ccaacagtaa tgccgcgttt ttatcatttt
    21541 ccagctgcac atgcccctga gcgtcactgg ttgcctgagt cagagtctgc cctttctcat
    21601 ttaataaaga gacttcaatt ccttgctggg ccgcgccgtt ttccagactt tgggtaaaga
    21661 tatccagacg attgtgataa cggtgagctg aaacgccgat atcacttaac gtaaacagcg
    21721 tcgcgggatt actgtaatcg taacgtccag cctgattcat cacagccaga tacacgcccg
    21781 cctgctgaag cggtttgata tcgcccagcg gcagcaataa tttttcacgg gtgttacgcg
    21841 caggattgag atcaaaccgt ccggtgtaga ccagatccgc catctgcagc agtttgtctg
    21901 actgccagtt cgccagcgaa ttgcggtatt cccattggct aatgaatgct ggcagagatt
    21961 ctggcttaac gcggaagaag ttaacatcga cattattaac gttgagcgcc attaccggca
    22021 gcccttcaac gactttacca ggcagcagcg aaccacggct ggcaaaaccg acgctgggtt
    22081 ggatgtcgcg ggtagttata gttttttcgt aatctttact gaaggttgcg ttgttgagtg
    22141 ctttgacctc cttgccaata gtaacgatca aatcacgttt cggttcgagg tggcgtaaac
    22201 gtaactcttt aagattatct gacagctccc aggcaccatc cactttgccg ctttttttat
    22261 cgacgacatg aataacgcgt gagaaatcct gatccgggtc gagagggatg gagaacgtca
    22321 gcaccagcgt ggctgcacca tcaagttgga cttcagagag atccagcaat gtcagcacct
    22381 taccggcact ctgttgggcc agtttttgtc tctccggcac ggagagtttt gctgaactcg
    22441 cgttttctga agaggccgct ttagtaactt cagaaggcgc atcttttttc accgctgttg
    22501 gcgcgttatc gttgttgtcg caccctgcca gcgccagcat tagcatgcag gcggctacgc
    22561 gtaacttttt catttttcat ccctgccaca atggcccgtt agcaacgtcg aataattatt
    22621 atgcgtgaga atttacgtta tgtaattcag tatcacgccc atacaatccg aattttagtg
    22681 agaattgtgg ctcagacagc caaatcagcc tctttcgctt gtcgcttttc actaaacatc
    22741 cgacaattta gcctaacccc ggcaaaaatg gagatgccta tgtccacgac atggtttgta
    22801 ggagccgact ggctcgccga acatattgat gacccggaaa ttcagattat cgatgcccgc
    22861 atggcgtcgc ctggacagga agatcgtaac gttgctcagg agtatctgaa tggacatatt
    22921 cccggcgcag tgttttttga tatcgaagcg ctttctgatc acacttcccc gcttccgcac
    22981 atgctgccgc gcccggaaac gttcgccgtg gcgatgcgtg aattaggcgt taaccaggat
    23041 aagcacctga ttgtctatga cgaaggtaat cttttctcag ccccacgagc atggtggatg
    23101 ctgcgcacct ttggtgtaga gaaagtgtcg attctggggg gtggacttgc aggctggcag
    23161 cgcgatgatc tgctgttaga agaaggtgca gtagagctgc cggaaggaga gtttaacgcc
    23221 gcgtttaatc ctgaagccgt ggtgaaagta accgatgtat tattggcaag ccatgaaaat
    23281 acggcgcaaa ttattgatgc ccgcccggct gcacgtttta acgtagaagt tgatgaacct
    23341 cgcccaggtt tacgtcgcgg acatattccc ggagcactga atgttccgtg gacggaactg
    23401 gtgcgcgaag gcgaactaaa aacgaccgat gaactggatg cgatattttt tggtcgcggc
    23461 gtcagctacg acaaaccaat tatcgtcagc tgcggctctg gtgtaacggc agccgtggtt
    23521 ttgttagcac tcgcgacgct ggatgtgcca aacgtgaaac tgtacgacgg cgcatggagt
    23581 gaatggggcg cgcgggcaga tttaccggtt gagccagtga aataagtatt ttacaggcaa
    23641 taaaaaaccg ccgaatttgg cggtttttta ttgctggtct ggttcgcggc ctttccagca
    23701 ggttgtatta ccgtagtaat gcaagcgcgt ctcagcggag acaatactcg ccagtaactc
    23761 tctttttgtc aagcaaaaga gagttattat tgttctgtta gtgtattatc cactgcggcc
    23821 ctttccgccg tctcgcaagc gggcgctggc ttaaggaaag gatgttccgc gaccgttaga
    23881 gcaagcgcgt ctcagcgctt gctatcgcgg caatatcgcc agtggtgctg tcgtgatgcg
    23941 gtcttcgcat ggaccgcaca atgaagatac ggtgcttctg tatcgtactt attgtttctg
    24001 gtgcgctgtt ttcccaagta aataataacc ggagtctctc cggcgacaat ttactggtgg
    24061 ttaacaacct tcagagcagc aagtaagccc gaatgccgcc ctttggggcg gcatatttta
    24121 gattatccga ttctgtttaa agtcacgcaa aaaaccaccc cagcgacgtt catagaatgg
    24181 cacaatatgt tcggtaataa agtggctaat tcctttttcc ccttttttca cctgacaaat
    24241 atcgattggt tcatcgccag gtaatgtatc ggtcgctaca cttcccgtcg cctgaataat
    24301 ttcttcgata tcaccatcgg cttcaatgcc aataagtaaa ttaggctgtg cctcttcgtt
    24361 ctctttaatt gaacaaataa aagcacgctt caccgactta atggttttaa ataaggtggt
    24421 gagtgaatca atcatttgtg ctggcggctc tgcgacttcc gataatatca gcgattcacc
    24481 gccttccagg atttcctggc tgctcagcgg atttccctct tcaccaatca acaaactgat
    24541 ttcacgcggc ataaattctt taccggtcgg cagtttggca ttaaggaaga gcgtttcgcc
    24601 aagggtcatc tcaaacaatg tgcgaacggg cattacgaca aatgcctgtt cgtcttcaac
    24661 cgcctgttga agcgcttcta acgaggtgaa aaaaggaatg acgctggtgc cgtcttcttt
    24721 ttcccagtgc tgtaaatcaa gcgcactatc ttcaaccaca gcctcgccct gcgccgccgt
    24781 accaggcacc cagacggtgg attccagtag agtacggaaa aaggccgggc ggtgcgccgg
    24841 ttcggttgct gctttttcca gcaggtcttc aagttcgttt tttgtttcgg acatatgaac
    24901 cacaattcat tcaacgttcg gggcgcaaat gcctgatgcg ctacgcttat caggcctaca
    24961 agggattcgc aatttgttga atttgcagaa tttgtaggcc ggataaggcg tttacgccgc
    25021 atccggcata ttagtttacg ccgttaacag attagcaatc gtgcgcacac caagtcccgt
    25081 agcgcccgca gaccactgtt caaccggcgc tttacggtaa gtcgccgagc agtcgatatg
    25141 cagccagcct tgctgatagt tctcaacaaa gtgcgacagg aagcccgccg ccgtgctcgc
    25201 gcctgccgga tacgccgcgc ttccggtatt gttcagttcg gcaaagttag acggcagctg
    25261 gctgcggtgg aattccgcca gcggcagacg ccagaacggt tcgttctctt gtgaggcact
    25321 cgccagcaaa cgaccggcaa gcgcatcgtc aaaactgaac agcgcgtgat aatcattacc
    25381 cagcgcagtt ttcgccgccc cggtgagggt cgccgcatca atgatcagtt ccggtttctg
    25441 cgcactggca tcaatcagac catcggccag caccagacgc ccttcggcat cagtgttcat
    25501 cacttcaact tttttaccgt tgcgataggt gatgatatcg cccagcttga acgcattgcc
    25561 gctaatcagg ttatccgcac agcagaggaa cagcttcacg cgcttgttca gtccgcgcgt
    25621 aatggcaaat gccagcgccc cggtaaccgt tgccgcgccg cccatgtccg acttcatcga
    25681 gtccataaac gcagtctgtt ttatgctgta gccgccggag tcaaaagtga tacctttacc
    25741 taccaggcac gcgtacaccg gtgcttcttt atcgccagtt gggttgtaat ccagcgccag
    25801 caataccgga gaacgttctg aaccgcgccc gacagtgtgc agccccatat aaccttgctc
    25861 acgcagatct tcgcctttgg tgatccgata agtcacacga tcgcccgcga cgttgctgat
    25921 cagatcaaca gcacgctgtg ccagttgcga tggtcccaat tcttctgccg gtgcgttgat
    25981 ggtgtcacgc acccagtcga tgatcatcag gcggttatcc agttcctggc gctgggcatc
    26041 gtccagatcc ggccactcca ctttacgcgt gcctttcggg gctttgtaac cttgccagaa
    26101 tgcccagcag cgatccgcat cccagccttc accgcttaac tgaacatgct tgatgcccag
    26161 accgtcaatc ttgcgcgccg cacgctggat cagccccaga tcgtctgccc cgttcaaatg
    26221 cagggtaatg ccgtcattat taatgctgta agttgctttt tctccccagc gcgcgtcggc
    26281 aggttgggta gagagggtaa tcttcatcgc ttctgtcatt ttagttatcc ttctttgtaa
    26341 aagggccgcc agttggcagc cccaggattt ttccgctaaa tgattcgcgt tgcaggaagg
    26401 cggcaagtga gtgaagcccc aggagcatag ataactatgt gactggggtg aacgagcgca
    26461 gccaacgcat ctgcggcgtg aagcatgacg cggaaattat tcggcctcgt ccagccagac
    26521 taacaaaatc gcttcgagga ttttctcgtt ggatgcctgc gggtcgtcgt cgaaatcttc
    26581 cagatcgcaa atccactgat gcatatcggt gaatcgaacc gttttcggat caagatcggg
    26641 atacgcatcg tacagtgctt cgccaatttc gcggctatcg gtccatttaa gtcccatact
    26701 aacctctgtt aatgctcacg cgcatggttg atagtgtaac gcgggatttc gaccactaaa
    26761 tcttcgtcgg tgacgcgcgc ctggcagctt aaacggcttt ccggctccag tccccaggct
    26821 ttgtccagca tgtcgtcttc ctgctctgag ctttccggca gcgagtcaaa accttcacga
    26881 acgatgcagt ggcaggtggt gcaagcacag gatttttcac aggcgtgttc aatctcgata
    26941 ccgttacgca gagctgcgtc gagaatggtt tcaccgctat tagcttccag aacagcgcca
    27001 tcagggcaga gatcctgatg aggcaaaata acaatctttg gcatattaaa cctcgtccac
    27061 ggaatggcct ttcagcgcac gacgaaccga ctggtccatg cggcgagcgg cgaaatcctg
    27121 ggtttgtttg tctacgtttt taatcgcttg ttcgatggcg tcaacgtcat cgccctgcgc
    27181 cacttcactc aggtgagcgg cagcatcgtc aatgacctga cgttctgcgg cgcttaacag
    27241 cgcggcatca gcagccagcg cgccgtgcag actttccagc acacgcgccg cttctacttt
    27301 ttgttctgcc agcattcggg cttttacgtc ctgctcggca tagctcattg agtctttgat
    27361 catcgaagcg atttcgctat cggtcagacc gtaagacggt ttgacctgaa tagacgcctc
    27421 aacgccggtg gatttctcca tcgccgtcac gctcaaaaga ccgtcggcat cgacctggaa
    27481 cgtcacgcga atatgcgcac caccagccgg tagcgccgga ataccacgca gcgcaaaacg
    27541 cgccagtgag cggcagtcct gcaccagttc gcgctcaccc tgcattacat ggatagacat
    27601 cgccgtctga ccatctttaa aggtggtgaa atcctgagcg cgggccaccg gaatagtggt
    27661 attacgcgga atcactttct ccaccaggcc gcccatcgtt tcgaggccca gcgacagtgg
    27721 gatcacatca agcagcagca tttcgctgtc tggcttgtta cccaccagaa tatccgcctg
    27781 aatcgccgcg ccaatagcga cgactttatc cgggtcgatg gaagtcagcg gtggacgacc
    27841 gaaaaattcg cctacccgtt cacgcaccag cggcacgcga gtagaaccgc ccaccatcac
    27901 cacttccagc acttcatcag cttctacacc cgcgtctttc agcgcgcgac gacaagccag
    27961 taaggttcgt tttaccagtg gcgcgatcag ttcattgaat tgttcacggc tgatttcgcc
    28021 ctgccagccc gcaacgttaa cggtcacgga gtccgcatcg ctcagcgcga ttttggctgc
    28081 aatggcggca tccagcagtt cacgctgaac gcggttatcg ctacgatcag gaatgcccgc
    28141 ctgctcgcga atgtaatccg ccagcagatg gtcgaaatca tcgccgccga gcgcggaatc
    28201 accgccggtt gccagcactt caaacacgcc gcgacttaag cgcagaatgg aaatatcaaa
    28261 cgtcccgcca ccgaggtcat aaacagcgat cacgccttcc tgaccggaat ccagcccgta
    28321 ggcgatagcc gcagcggtcg gttcgttaag taagcgcaga acatgcaacc ccgccagacg
    28381 cgccgcgtct ttggtgccct gacgctgggc atcgtcaaag tacgccggaa cggtgataac
    28441 tacaccatcc agctcgcctg ccagggcttc agttgcccgc gccgccagtg ctttgaggat
    28501 gtccgcagaa acgcgcaccg ggttcagcag ccccgccgcc gtttcaatca tcggcaggcc
    28561 gttttcgctg gcctggaatt gataaggcag atgcggatag cgttgctgga tatcagccag
    28621 cgagcgtccc atcaggcgtt taacagaact aatggtgttg gcggtatcaa gcgctgcgtt
    28681 agtacgcgcg tcataaccca ccgaatgccc ttgctgttga tagtgaacaa cagatggcag
    28741 caggtgacgg ccttcatggt cggctaacgt ttcggcctga ccgctgcgca ctgtcgccac
    28801 cagcgagttg gttgtgccca ggtcaatacc agccgccaga cgacgctgat gcggcgcagc
    28861 actcaaacca ggttcactaa tttgtaataa ggccatgttt agcttccaga aattaaaaat
    28921 cgagcagttt ttcttcgagt tgttcggcac tgctccgcag tttatcgaga aaacgcagct
    28981 tacgcacggt atccgccgcc gcgtcccacg cctcgttgtc taactgttca accatcaact
    29041 gatggcgggt atcaaacatc tttttcacac gtttgataaa gctttccagc cgcgcttcat
    29101 ctttcgcctg ttcgatctcg tccagctctt cgcgcagctc caactgttcc atcaggaacg
    29161 cggtgtcgcg cacagtatgc tgctcgctgg cgagatcaaa accgtgtaaa gaaagcaaat
    29221 attccgcgcg cattaacgga tgacgcagcg tttgccaggc ctggttaatg gttgcagatt
    29281 gctgtacggc ggcgagttgt tccgcctggc ttccgctggc gaatttatca ggatgatact
    29341 gacgttgtag atcctgaaaa cgcaggctca gcgcctgggt atcgagttga taacgggcag
    29401 gcaagccaaa gagggtgaag taatccataa cattctcagg gctgcgatcc gccgcgataa
    29461 cggcgaatca ggtaaaacaa accccacgcg caggcgacca cggtggggtt atcggtatgc
    29521 gcatcaaacg tggaagcttt cgccgcaacc acactcatct ttaacgttcg ggttggtgaa
    29581 tttaaaccct tcattcaggc cttcttttac gaagtccagc tgcgtaccgt ccagaaattg
    29641 caggcttttg ccatcgacca cgactttcac gcctttgtct tcaaacacga tgtcttccgg
    29701 cgtcggttcg tcaacaaatt ccagtacata agccatacct gaacatccgg aggttctcac
    29761 gcccagacgc aggccaaacc ctttgccgcg gttagccaga aaggtattta ctcgcgctgc
    29821 tgcactgtcg ctcagtgtaa tcgacataac caaacctcaa ctcttatttt gcttcacgtt
    29881 tgcttttata gtccgcaatg gcggctttga tcgcgtcttc tgccagaata gaacagtgaa
    29941 ttttcaccgg cggcagttca agttcttcag caatatcggt gtttttgatc gcctgcgctt
    30001 cgtcgagaga cttccctttc acccattcgg tgaccaggga gctggaagcg atagcagaac
    30061 cgcagccgta agttttaaaa cgcgcgtctt caatgatacc ttcatcgttg actttaatct
    30121 gcaacttcat cacgtcgcca caggccggtg cccccaccat gccgctgccg acgttctcgt
    30181 cgttgttgtc aaaggaaccc acgttacgcg gattctcgta atggtcgata actttttcgc
    30241 tgtaagccat tataaattct cctgattccg ataccgatta atgatgagcc cattcgatgc
    30301 tgttcagatc cacgccctgc ttgtacattt cccacagcgg agaaaggtca cgcagacgac
    30361 cgatggattt acgaactaac tcgatggtgt agtcgatctc ttcttcagta gtaaaacgac
    30421 ctaaagagaa acggatagag ctatgtgcca gctcgtcgtt cagccccagc gcgcgcagca
    30481 cgtaggacgg ttcgaggctt gctgacgtac aggcggaacc tgaagaaact gcgaggtctt
    30541 tcagcgccat aatcagcgac tcaccttcaa cgtagttgaa gctgacgttg agaatgttcg
    30601 gcgcaccgtg ttccaggtca ccgttcaggt aaacttcttc gatatctttg atgccgttcc
    30661 acagacggtt acgcaggccg cgcagacgtt ccatctcggt cgccatctct tcttttgcga
    30721 tgcgataggc ctcgcccatt ccgacgatct ggtgaacagg cagagtgccg gaacgcatac
    30781 cgcgctcgtg accgccgccg tgcatttgcg cttcgatgcg tacgcgcggt ttacgacgta
    30841 catacagcgc accgatacct ttcgggccat agattttgtg accggagaaa gacatcaggt
    30901 caactttcaa ctggctcagg tcgataggca gtttacccac gctctgggtt gcatcaacgt
    30961 gatagataat gccacgagca cggcacattt cgccgatagc cgcgatatcc tgcaccacgc
    31021 cgatttcgtt atttacgtgc atgatggaaa caaggatggt gtcgtcacgc atcgctgctt
    31081 caagttcttt caggtcgata atgccgttac gctgcggtgc caggtaggtg acttcaaaac
    31141 cttcgcgctc cagctgacgg caggtatcca gtaccgcttt gtgttcggtt ttgctggtga
    31201 tgatgtgctt gccttttttc tgataaaagt tggctgcacc tttgatcgcc aggttgtcag
    31261 attcggttgc accagaggta aagacgattt cacgcggatc agcgccgacc agatcggcaa
    31321 tctgattacg ggcgatatct accgcttctt cagcctgcca gccgaaacgg tgagaacgag
    31381 aggccgggtt accaaaggtt ccgtccatcg tcatgaactg catcattttc tcggcaacac
    31441 gcgggtccac cggcgtggtt gcggagtagt cgagataaat cggtaatttc attgctctat
    31501 aaactccgta catcactcaa tgcaaggaac caggctaccg gctggatgta cgaccgtgtt
    31561 tacggagcgc gatacgcccc ggcctgattc tgaattcttt ttattaagcg cgtaacttaa
    31621 cgtcgatcgc gtcttgtatg cgggtgcgtg gcgcgtcgtg agtatgctga cgaccagaca
    31681 catccagcac ttcctggtta ttaaccagtt cgcctaaagt aatgttgttg agaaaaccgg
    31741 tgagacggtc gctcaaatca cgccacagcg cgtgggtcag gcatttatcg ccgccctggc
    31801 agccgccttt accctgacaa cgggtggcat ctacagattc gtcaacggcg ctaatcactt
    31861 cgccaacggc gatgctgctg gcatctttgc ctaacagata accaccgcct ggtccacgta
    31921 cgctggaaac cagaccattt ttacgcagac gggaaaacag ttgttccaga taagaaaggg
    31981 aaattccctg acgttcggaa atatcagcca acggtaccgg gcccgcttca gagttgagcg
    32041 caacgtcaag cattgcggtc acggcatagc gccctttaga tgtcagtctc atgtcttact
    32101 tcacctcaaa ctcgcccctg cccggggttt tttattgtaa aagtgggggt attgcatagc
    32161 agggtcaagt ctgacattcc cgagtaaatt ggtcaactat ttacttgact gatttagtcg
    32221 ggtatttaac cttcagtgcc atttttttat cgtggcgttt gtacctgttg tccttccaga
    32281 ccatgggcgg gttgagggca attattcgca ttagcgctgg cctcttcccc tcaccctaac
    32341 cctctccccg aaggggcgag gggaccgtcc gtgcatttat ctggcttagc cctcaggcct
    32401 tattaccttt attctgctgc tcaatagaag ccagaatccc gcgcaggata ttcaattcct
    32461 ggctttccgg gcgcgcacgg gtaaacagac ggcgcaattt attcatcacc tgccccggat
    32521 ggttttcacg gataaaaccg gttgccagca gcgtttgttc cagatgacca taaaaacgct
    32581 ccagatcatc gaccagcgga tacggcgtct cttcatgctc gacctgctcg ccgttttcct
    32641 gagttgccag ccaggccatg cgcacttcat aggcaataac ctgaaccgcc atcgccaggt
    32701 tcagcgagct gtattccggg ttagccgcaa tcgcgacatg ataatggcat ttctgcaact
    32761 cttcattggt caagccgacg cgctcacgac caaacaccag cgccaccggg gtatttgccg
    32821 cttcagcgac gcttttcaga ccgcattcgc gcgggtcgag catcggccac ggcagcgtgc
    32881 gggagcgtgc gctggtgccc accaccaggc tacaaccggc taacgcttcg tcgagcgtat
    32941 cgacgatgtg agcattacca atcacatcgc tggcccctgc tgccagggca atcgcctggg
    33001 agtcgggttt caccagtgga ttaaccagcc acagattggt taatcccatt gttttcatgg
    33061 cacgggcaac agaacccata ttgccggtgt gtgacgtctc caccagcaca attcgaatat
    33121 tttgcagcat tgtctttctt catctaaaga ttattcacgc atcttatcat aaaacgaaga
    33181 cagatgccga tctcgctgct atactctgcg ccgttttccc gttctttaac atccagtgag
    33241 agagaccgat gcatccgatg ctgaacatcg ccgtgcgcgc agcgcgcaag gcgggtaatt
    33301 taattgccaa aaactatgaa accccggacg ctgtagaagc gagccagaaa ggcagtaacg
    33361 atttcgtgac caacgtagat aaagctgccg aagcggtgat tatcgacacg attcgtaaat
    33421 cttacccaca gcacaccatc atcaccgaag aaagcggtga acttgaaggt actgatcagg
    33481 atgttcaatg ggttatcgat ccactggatg gtactaccaa ctttatcaaa cgtctgccgc
    33541 acttcgcggt atctatcgcc gttcgtatca aaggccgcac cgaagttgct gtggtatacg
    33601 atcctatgcg taacgaactg ttcaccgcca ctcgcggtca gggcgcacag ctgaacggct
    33661 accgtctgcg cggtagcacc gctcgcgatc tcgacggtac cattctggcg accggcttcc
    33721 cgttcaaagc aaaacagtac gccactacct acatcaacat cgtcggcaaa ctgttcaacg
    33781 aatgtgcaga cttccgtcgt accggttctg cggcgctgga tctggcttac gtcgctgcgg
    33841 gtcgtgttga cggtttcttt gaaatcggtc tgcgtccgtg ggatttcgcg gcaggcgagc
    33901 tgctggttcg tgaagcgggc ggcatcgtca gcgacttcac cggtggtcat aactatatgc
    33961 tgaccggtaa catcgttgct ggtaacccac gtgttgtgaa agccatgctg gcgaacatgc
    34021 gtgacgagtt aagcgacgct ctgaagcgtt aatgactcag gcgggtgatg tcactcaccc
    34081 gccctcgcct ttcaggcgct attctgaaat acttcctcac cgctttactt tctttcgtca
    34141 ctctcccacc atctttcccc gattaatgga tgataaagaa gtcgcaagga aaggttatgg
    34201 cactgccagt gaacaaacgc gttcccaaaa ttctgtttat tctctttgtt gttgccttct
    34261 gcgtttattt agtgccgcgc gttgccatca acttcttcta ttatcctgac gataaaattt
    34321 acggtcccga cccctggtcg gcggaatccg tcgaatttac ggctaaggac ggtactcgtc
    34381 tgcaaggctg gtttattcct tcttcgacgg gccctgctga caacgccatc gcaaccatca
    34441 ttcatgctca cggcaatgcc ggaaatatgt ccgcccactg gccgctggtc agttggttac
    34501 ctgagcgtaa tttcaacgtt tttatgtttg attatcgcgg gtttggtaaa tcaaaaggca
    34561 cgccgtccca agccggattg ctggacgata cgcaaagtgc catcaatgtg gtgcgccatc
    34621 gcagtgatgt aaacccacaa cgtctggtgc tgttcgggca gagtattggc ggggcgaata
    34681 ttctggatgt tattggtcgg ggtgatcgtg aaggcatacg tgcggtgatc ctcgactcca
    34741 catttgcctc ttatgcaacc atcgccaacc agatgatccc cggcagtggc tacttacttg
    34801 atgagagtta cagcggcgaa aattatatcg ccagcgtcag cccgatcccg cttttactca
    34861 ttcacggtaa agctgatcac gttatcccat ggcagcacag cgaaaagttg tatagcctgg
    34921 caaaagagcc aaaacggttg atcctaatcc cggatggcga acacattgat gctttttccg
    34981 atcgtcacgg cgatgtttat cgcgaacaga tggtggactt tatccttagc gcgttgaatc
    35041 cacagaacta acccatgatc gctagcacga taatcattca caaaaccacc ttaagacatg
    35101 ctaatccact ggtcagaaca gtttaagatg agaaaaattc tgtgacgctt gccaacattt
    35161 ctgatgatta gcattccctt cgccatttcc ctgagcaaac tttagctatt cttatcaatt
    35221 atgcttatgg gagatctaca gatgatgcct acgcttgctc caccatctgt cctttcggct
    35281 ccccagcgcc gctgccagat cttgctgacg ctctttcagc cggggttgac cgccaccatg
    35341 gcaaccttca gcgagcttaa tggtgtggat gatgatattg ccagtcttga tatcagcgaa
    35401 acaggacggg agatcctgcg ctatcatcaa ctcacactga cgactggtta tgacggtagc
    35461 taccgggttg aaggtacagt gcttaaccaa cgtttgtgtt tatttcactg gctacgacgt
    35521 ggtttccgtc tgtgtccgtc atttattacc agccaattca cccccgccct gaagagtgaa
    35581 ctgaagcggc gcggaattgc gcgtaacttt tacgacgata ccaatctaca agcgttagtg
    35641 aatctctgct cccgacggct gcaaaaacgc tttgaatcgc gcgatattca tttcctgtgt
    35701 ctgtatctgc aatattgttt gctgcagcac cacgctggaa ttacgcctca gtttaatccg
    35761 ctccaacgtc gctgggtgga atcctgcctt gaatttcagg tagcgcagga aattggacgc
    35821 cactggcagc gtcgggcgct ccagcctgta ccgcctgatg agccactgtt tatggcacta
    35881 cttttttcca tgttgcgggt tcccgatcca ctgcgggatg cgcatcagcg agacagacaa
    35941 ttgcgtcagt ctatcaaacg tctggtaaac cattttcgtg agctgggaaa tgttcgtttt
    36001 tatgatgaac aggggttatg tgatcagctt tatacccacc tcgcccaggc gttaaatcgc
    36061 agtttgtttg ccatcggtat tgataatacc ctgccggaag agttcgccag actgtaccca
    36121 cgcctggtgc gcaccacccg cgcggcgctg gccggatttg aaagtgaata cggcgtccat
    36181 ctttctgatg aggaaagtgg tctggtcgcg gtgattttcg gtgcctggct aatgcaggaa
    36241 aacgatctgc atgaaaaaca gattattcta ctgaccggga atgatagcga gcgagaagcg
    36301 cagattgagc agcagttacg cgaactaacg ttactgccgc tcaacattaa gcatatgtcg
    36361 gtaaaggcat ttttgcagac aggcgctccg cgtggcgcgg cactgattat tgcgccttat
    36421 accatgccat taccgctctt ttcaccaccg ctgatctata cggacctgac gctgacaaca
    36481 catcaacagg agcagatccg caaaatgctc gaatcagcat gagggaacaa ctttcgggcg
    36541 caaaaacatt gccggtagcg ccaccagcgc cattacccag aacacgccgt ggcccagata
    36601 ttgatacagg aaaccggcga aaacggtcat gatagcgata ctgccgccca tcgcgacggc
    36661 agagtaaacc gcctgtaaac ggatgacttc gctaccctgg cgagcagcaa tataacgcat
    36721 ggcggccagg tggcagaccg tgaaggtgcc gcaatgcaga atttgcacca ctatcaacca
    36781 cggcaacgcc gtagttgctc ccataatgcc ccagcgcact acgccgcaaa tcgccgagat
    36841 caacagcata tcgcgtgcac tacaacggcg gaaaagttta ttactcagcg caaagataat
    36901 gacttccgcc accacgccca gcgaccacaa ataccccacc gccgaggccg agtagccagc
    36961 tgcctgccag taaatggcgc taaaaccgta ataggccgca tgtgccccct gcaataaaca
    37021 aacgcaggcc agaaagcgcc agttctggcg aaccagcgcc aaccacgcag accaaccggt
    37081 gctctcctgc tggcgacttg ccccttgtgg ctgaatcgtc ggacggatga gaaagccgag
    37141 cagcatggat gccacgccca atgttaacag cgcgaggatc acctgataat caaacatagt
    37201 gaccagtttg cccgtcagcg ccgagccaat gacaaacgcc accgagcccc acagtcgcac
    37261 tttgccgtaa tcaagcggga actgcttttg ccacgtattc gccagtgcat cggtcaacgg
    37321 taccagcggt gagaaaaaga ggttaaagcc aatcatcacc agcatcagcc acgctacgtg
    37381 cgcccccgcc cagaaggcga cagcaaagag aagtgtcagc agtgccagca cgcgcaaggc
    37441 ggaaatcagg cgggaaggat cgctgacgcg gggcgcgatg agcaaactcc cgagaaaacg
    37501 ggcaaccaga cctgccccca ataacaggcc gatggtttct ggcgttaaac caatcccttt
    37561 aagccagacg ctccagaaag gtagaaaaat gccgtaacta aaaaagtatg tgaaatagcc
    37621 gagcgccaac cagcgcgtgg attgcaaaac catgagtccc tcccgtcagg aggcgttagt
    37681 ctggggttaa tcgaatgttg gtgcaagttg aaaaataaga atattcgagc ctgcttcccg
    37741 atgtctgtaa cgccagttca caagcactaa aaaactgcga tccgcgacgc atgttgcaaa
    37801 aataatgcgt aattatgccg ttacgcttgc caaacgttcc tgcacaatgg cgatgaaatc
    37861 gcgtaatgcc ggcttcatct cccctttctt ccacgccatc agtaaagcaa tggaaggcac
    37921 atttccggca atgggacgaa aaacaacctg cccggtatta aaattattca tataaccggg
    37981 tatcaaagtg acgcccagcc ccatgcccac cagattcatg gtcaccagaa tattcgttgc
    38041 cacctggacg atatttggct ggctgttttc ttgcgcaaac cacgctttaa cgatcggcgc
    38101 aagcgaaccg gaatacgccg gatcggtact gacgaaattc acgccatcca gttgcgcggc
    38161 ggtgatctct ttttcatgtg ctaaagggtg atcaaccggt aacaccacca ctaatggttc
    38221 gtcaaaaagc tccagataat caatctccgg gctataaaca ggatggcgca ttaagccgac
    38281 gtcgagttca ccacggcgaa ttttttcctc ctgttgcgtg gtgattaaac tcaccagctc
    38341 aatcaaggtg tctggctgtc tgagacgaaa catcggtaat acttttggca gtaaattcac
    38401 ttccgccgat ggcacaaagc caatggttaa ttgtctgtct tcctgaacaa ttttccgcgc
    38461 ccgtaatttg gcattttccg cttgttcgag gattgccagc gcgtcctgga gaaaacattc
    38521 tcccgccgct gtcaacgcga ctttgcgctt atccctcacc agtaacggaa caccgacaca
    38581 gttttcaaga tcgcggatct ggctgcttaa cgaaggctgt gaggtatgca gtttttccgc
    38641 cgcacgggta aagttcagtg cctgcgccac tgcgacgaaa tagcgtaaat gccgtagttc
    38701 catcaccttc cccttgttat cgaaaaaacg tctcagctgg tagaaattaa ctatttcaca
    38761 tattagcaac caaccagcaa catccttatg gcacaaaaat agaaggtcaa tacatcttat
    38821 ctttcaggat taaaaaatat gaccacaccc tcagatttga acatttacca actgattgac
    38881 acccaaaatg gtcgggtcac tccgcgtatt tataccgacc cggatattta ccaactggag
    38941 cttgagcgta ttttcggtcg ttgctggcta tttctcgccc acgaaagcca gatcccaaaa
    39001 cccggtgatt tctttaacac ctacatggga gaagatgcgg ttgtcgtagt gcgtcagaaa
    39061 gacggcagca tcaaggcgtt tctcaaccaa tgccgccacc gggccatgcg tgtgagttat
    39121 gcagattgcg gcaacactcg cgcctttacc tgcccgtatc acggctggtc ttatggcatt
    39181 aacggcgagt tgatcgatgt accgctggaa cctcgcgcct acccacaagg gttgtgtaaa
    39241 tcccactggg gactaaacga agttccttgt gtggagagtt ataaagggct gatttttggc
    39301 aactgggata ccagcgcacc gggcctgcgt gattacctgg gtgacattgc ctggtatctg
    39361 gatggcatgc tggatcgtcg cgaaggcggc accgaaattg tcggcggcgt acaaaagtgg
    39421 gtgatcaact gtaactggaa attcccggca gagcagttcg ccagtgacca gtatcatgct
    39481 ctgttcagcc atgcttctgc cgttcaggta ttaggggcga aagatgatgg cagcgataag
    39541 cgcctcggtg atggacaaac cgcccgcccg gtgtgggaaa ccgccaaaga tgcgctgcaa
    39601 tttggtcagg acggtcacgg tagcggtttc ttctttactg aaaaaccgga tgctaatgtc
    39661 tgggtcgatg gcgcagtttc aagctattac cgcgaaacct atgccgaagc agaacaacgt
    39721 ttaggtgaag ttcgcgccct gcgcctggcg ggtcataaca atattttccc cacgctttca
    39781 tggctaaacg gcactgccac actccgcgtc tggcatccgc gcggccctga tcaagttgaa
    39841 gtgtgggcgt tctgtattac tgacaaagcc gcctccgatg aagttaaagc cgcttttgaa
    39901 aacagcgcca ctcgtgcttt tggtcctgct ggttttctcg agcaggatga ctcggagaac
    39961 tggtgtgaaa tccagaaatt gcttaaaggc caccgcgccc gcaacagcaa actgtgtctg
    40021 gaaatggggc ttggtcagga aaagcgccgc gacgacggca ttcctggcat tactaactat
    40081 atcttttcag aaactgccgc tcgtggaatg taccaacgct gggccgatct tctgagtagc
    40141 gaaagctggc aggaagtgct cgataaaacc gccgcttacc agcaggaggt gatgaaatga
    40201 gtgcgcaagt ttcactagag ttacatcacc gcattagcca gtttctcttt cacgaagcca
    40261 gcttactgga cgactggaaa tttcgtgact ggctggcgca gctcgacgaa gagattcgtt
    40321 acaccatgcg caccacagtt aacgcgcaaa cacgcgaccg ccgcaaaggc gtccagccac
    40381 cgacaacctg gatttttaat gacaccaaag accagctgga gcggcgaatc gcccgtctgg
    40441 aaacgggcat ggcctgggca gaagagccgc cgtcacgcac ccgtcactta atcagcaact
    40501 gccagataag cgaaaccgac atcccaaacg tatttgctgt gcgggtaaat tatctgcttt
    40561 atcgggcaca aaaagagcgc gatgaaacat tctatgttgg aacgcgtttc gacaaagttc
    40621 gccgtctgga agatgacaac tggcgcttgc tggaacggga tatcgtcctg gatcaagcgg
    40681 taatcacttc ccataacctg agtgtactgt tctgatgaat cgaatttatg cgtgtcccgt
    40741 tgcggatgtg ccggagggtg aggctctccg gatcgatacc tcgcccgtca tcgccctgtt
    40801 caacgttggc ggcgagtttt atgccattaa cgatcgttgc agccatggta atgcgtcgat
    40861 gtcagaaggg tatctggaag atgacgccac ggtggagtgc ccgctacacg ccgccagttt
    40921 ttgcctgaaa acggggaaag cgttatgcct gcccgccacc gatccgctca ccacttatcc
    40981 agtacacgtt gaaggtggtg acattttcat cgacttaccg gaggcgcagc catgagcgat
    41041 ctgcataacg agtccatttt tattaccggc ggcggatcgg gattagggct ggcgctggtc
    41101 gagcgattta tcgaagaagg cgcgcaggtt gccacgctgg aactgtcggc ggcaaaagtc
    41161 gccagtctgc gtcagcgatt tggcgaacat attctggcgg tggaaggtaa cgtgacctgt
    41221 tatgccgatt atcaacgcgc ggtcgatcag atcctgactc gttccggcaa gctggattgt
    41281 tttatcggca atgcaggcat ctgggatcac aatgcctcac tggttaatac tcccgcagag
    41341 acgctcgaaa ccggcttcca cgagctgttt aacgtcaacg tactcggtta cctgctgggc
    41401 gcaaaagcct gcgctccggc gttaatcgcc agtgaaggca gcatgatttt cacactgtca
    41461 aatgccgcct ggtatcctgg cggcggtggc ccgctgtaca ccgccagtaa acatgccgca
    41521 accggactta ttcgccaact ggcttatgaa ctggcaccga aagtgcgggt gaatggcgtc
    41581 ggcccgtgtg gtatggccag cgacctgcgc ggcccacagg cgctcgggca aagtgaaacc
    41641 tcgataatgc agtctctgac gccggagaaa attgccgcca ttttaccgct gcaatttttc
    41701 ccgcaaccgg cggattttac gggtccgtat gtgatgttgg catcgcggcg caataatcgc
    41761 gcattaagcg gtgtgatgat caacgctgat gcgggtttag cgattcgcgg cattcgccac
    41821 gtagcggctg ggctggatct ttaaggaagc acgatgaaag aaaaaaccat cattattgtc
    41881 ggtggcgggc aagcggcggc aatggctgcg gcctcgctac gccagcaagg gttcaccggt
    41941 gagctgcatc tgttttccga tgagcgacat cttccttatg aacgacctcc actctcgaaa
    42001 tccatgttgc tggaagattc cccgcagtta cagcaggtgt tacccgctaa ctggtggcag
    42061 gaaaacaatg ttcatctgca ttccggtgta accatcaaaa cgttgggtcg cgacacacga
    42121 gagttagtgt taaccaacgg cgaaagctgg cactgggatc agctttttat agcaaccggc
    42181 gcggcagctc gaccgctgcc gttgcttgat gcactgggag aacgctgctt taccctacgc
    42241 catgccggtg atgccgccag actgcgagaa gttctgcagc ccgaacggtc agtcgtgatt
    42301 gtcggtgccg gaactattgg tctggaactg gctgccagcg ccacgcagcg cagatgtaag
    42361 gtgacagtga ttgaactggc ggcaaccgtc atgggccgta atgcaccacc gcccgtgcaa
    42421 cgctatcttt tacagcgcca ccagcaggct ggtgtgcgca ttctgctcaa taatgccatt
    42481 gaacatgtgg tcgatggtga aaaagtagaa ctgacgctgc aaagtgggga aacgcttcag
    42541 gctgatgtgg tgatttacgg tattggtatc agcgccaacg agcaactggc tcgcgaggcc
    42601 aaccttgata ctgccaatgg cattgtcatt gatgaggctt gccgcacctg cgatcccgcg
    42661 atctttgccg gtggcgatgt ggcaatcact cgtcttgata atggtgcact acaccgctgc
    42721 gaaagctggg aaaacgccaa taaccaggcg caaattgccg ctgccgcaat gttagggcta
    42781 ccgctaccgc tactgccgcc gccgtggttc tggagcgatc agtacagtga taacttacag
    42841 tttattggcg atatgcgtgg cgatgactgg ctttgtcgtg gcaacccaga aactcagaag
    42901 gcgatttggt ttaatctgca aaacggcgtg cttatcggtg cggtcacgct gaatcagggg
    42961 cgtgagattc gcccaattcg caaatggatc cagagcggca aaacgtttga tgcgaaactg
    43021 ctgatagatg agaacatcgc gcttaaatca ctgtaaccag gataattagc gaatatctca
    43081 atgcctgggg cgtggcgagg tgcaagagtg tgtattacgt ttaaatcaca ttatcttgca
    43141 aagggattgg ttatgaacac actacgttat tttgattttg gagctgcccg ccccgttttg
    43201 ttattaattg cccgtatcgc cgtggtctta attttcatta tttttggttt tcccaaaatg
    43261 atgggctttg acggtacggt ccaatatatg gcctcgttgg gcgcgccgat gccgatgctg
    43321 gcagcgatta ttgcggtagt tatggaagtg cccgccgcga tattaatcgt gcttggcttt
    43381 ttcacccgtc cgctggcggt gctgtttatt ttctacacgc tgggtacggc ggtgattggt
    43441 caccattact gggatatgac cggcgatgcg gttgggccaa atatgattaa tttctggaag
    43501 aatgtcagta tcgctggcgc attcctgctg ctggcaatta ccgggccggg ggcaatttct
    43561 ctcgatcggc gttaggaaag atgccggatg cggcgtgaac gccttatccg gcatttaata
    43621 aattacagcc actctacccg caacgacatc tctgaagttg ttgattcccc tggtgctagc
    43681 gcaatgagat cacccccttc cgggcgatga tgatcatccg gcgcatggct catcggttcc
    43741 agacagaaga aatcaaacgc atatccttta tcaaacgcag ggtcggaaac aaagatgaaa
    43801 taacacggtg caggtggcgt cgtttccatg atgatggcat aaccttcctg cggctgctcg
    43861 atgcgggcct gaccattcca tccggcaaaa ccattgttca cccactggcg cggcaacggc
    43921 gcgggctggt taaaatccag ttcctgcggt agctgctcgc aaaactcacc cgccagccac
    43981 tgctcccgct ccagccagta accgctcgcc tgtgcctgaa tccgcgtttg cggcgacaac
    44041 ggaaaataag gatgccagcc ggtaccaaat ggcagcgtct ctgccccttg attggtgaca
    44101 gagagcgtca ccgtcagcgt atccgccgtt aaatgaaacg cctgacttac ccgatagtga
    44161 tagacaccgc tgcgatgttc atacaccaga cacaaactat catcgctgtg cgagacacat
    44221 tgccactcgc ccagccagcc atcgccgtgt agatagtgcg catcccactc aacattcggt
    44281 tgcagttgat actcacgccc ctgccagaca aaacgattgc cgctcacccg gtttgcaaat
    44341 ggcaccagcg gaaaacatga ggcatcggtt gccacaccgc tttttttacc aggacgtaag
    44401 agcggcgtcg tatcgcgcca gaagccttcg attacgccgc cctggtcaga aacgtccagc
    44461 tttagcgacc cgtgggataa ggtatagatg gtcatccgct aactccttaa tccgggaagt
    44521 taatcacaac tttcccgcat ttgccgctcg ccatcagcgc ataggcatca cctgcctgtt
    44581 ccagcgagaa gcgatgggta atggcgttac gcggccacag cttccagtcc gtcagatcat
    44641 gggcgcattt ttccatatgg aacagactgg tcacccagga gccgataatc cgccgttgat
    44701 ggtgcatcag atcggcgctg acctcgaatt ccacttttcc ggtttcacca atgtaaacca
    44761 cccgtcccca gtcagcggtg gattgcagtg ccagcaagcg acctgcggca ttaccggaac
    44821 aatcgagcgc aacatccgcg ccaccgtggg tgagttcggc gataatctgc ggcagacctt
    44881 cggtggttgc taaatagccg tgatccatca cccctaactg ttttgccatc gccagacgtt
    44941 ccggcagcat atcaacgccg atgatccgtt ttgcaccgcg acctttcgcc agcatcatcg
    45001 ccatcatgcc gaccggcccc agaccgacca ccagcacttt atcgctgccg gaaacttcgc
    45061 cgcgcaaaat cccttcatag gccgtgccaa cgccgcaact gataaacgca ccatcttcgt
    45121 agctcagcgc atccggcagg aggatcagat ctttttcttc cgccagcaga tattcggcat
    45181 gaccgccgtc acgctgccag ccgtaagccg cttttccttt gccagtacaa gagataggaa
    45241 agccgcggcg gcagttcggg caaaaaccac agccagaaat gtgatacacc agcacgcgat
    45301 caccctcttt aaaatggcga cagccttgcc ccatcgccac aatctgcccg cacggttcat
    45361 gaccgttgat aaatccctgg tataacggtt tatcgggtgc cgccgccgtg gcacggtgtt
    45421 gatgatagat atagtggaca tcgcttccgc aaatcccgga ggatttcatt ttgatcagta
    45481 cctggttaat ccccggcgtc ggcaccgcaa cttcccgcag atcgacggtc gaatttcctg
    45541 gtaaataagc tgccagcatc gttttcataa atccctcatt aacaatacga ttaattttca
    45601 tccctgccgc acccgcgcca ggggcgttaa ggtttagcgt ttcgctttac tgctacgctg
    45661 ggtcagcaag atattcgcca gcaccgccac cacgatgatg acgccgcgca ccacctgctg
    45721 gaaaaaggag ttaatcccga gcagcaccag accgttaccg attagcgtaa tcaccagcac
    45781 accaagcaat gtaccgaaca gggaaccgcg accgccggaa agtgccgtac cgccgaccac
    45841 gaccgcggcg atgacgtcaa actccagacc gtttgcggca cctgcgttac cagaaccgag
    45901 gcgcgccgcc aacaaaatgc cggtcaccgc cgctaataat cccgaaaggg taaagataag
    45961 aatgcgcacc cgacgaacgt tgatgccgca caactgcgcc gccgtagcat taccgccaac
    46021 ggcaaaaacc gagcgcccga aggcggtttt gcggctgatg aacacaaaca gcgcaaacaa
    46081 cacaatcatg atcagcgcgg ataccggcac accgagaaat tgtccgccca gccagtccag
    46141 cacctcgttt tcgtcaatcg gcactggcag tgcgttcgtc ataaacagcc ccattccgcg
    46201 cagggcgctc cacagcccca gtgtggcaac gaaacttggt acgttaaaca cgccgcgcag
    46261 caccccggcc agcgttccca tcagcgcgcc taacagcaac accagcagac acgccaccgc
    46321 cagcggaact tcaaattgca gcaaaaatgc caggcacacc gagacaaaag ccaccatcgg
    46381 cccaacgctg acatcaattt caccggagat aataatcagc gtcatcgccc aggcggcaat
    46441 cccaatggtg gcggcatcgc gcagcacgtt catctggtta ttcaatgaga taaagccagg
    46501 cgcgttcagg gagaagacca gataaagaat ggcgattacc accagcaaac cgatctcatt
    46561 aatatggcga ctgacaaatt gtttgagcga gacgctcttg ccctgcggca atgataatga
    46621 cgaagcagac atcttcaggt tcctcggtaa aattcatcag tgcacagaca gaatggcgga
    46681 catcagctca tccacattga ccggcgagtg aaactcctgc gagaacgtac cgtgctgtaa
    46741 caacaggatg cggtcgcaca ccagcggcaa ctcctccact tcactggaga taaacaccac
    46801 gctttttcct tcggcagcca gctcacggac aatacggtaa atctgctgtt tggcttcgat
    46861 atcgacgccg cgcgttggct cgtcgagcaa caaaatctgg ctggcggcat agacccaacg
    46921 accgatcacc actttttgct gattgccgcc agaaagcgtg ccgatgggcg tttcgctact
    46981 ggcggccttg accgtcatcc gctgcatcac ctcttcggtc aggcggcgga tggtggacca
    47041 ttgcagtacg ccgttggcgc tgattttttg ccgattggtc agcactgtat tttcgtcaac
    47101 gcccaaccag ggaatgatcc ccgcttcttt gcggttttct ggcgtatagc caatgccgcg
    47161 tttcagcatg tcgccgtaat cggggcgcgt gattttctcg ccgttgataa caatttcgcc
    47221 ctgttcatac tcctccagcc caacaatcgc cttcagcaat tcactgcgcc ctgcccccag
    47281 caggccagca atgccaagca cttcgccgcg acgtaacgta aagctgatat cctccagctt
    47341 gggcttatgg cgtaatgcac ggacttccag cacggcctga tcgacaattt cctgaggggc
    47401 taccggcgca atatcaacgt gatcgcgccc tagcattagc gacacaatat gatgcgtgga
    47461 ggtgttttcg agcatcacat cgcccgccac ctgaccatcg cgcataacgg tggcacagga
    47521 ggcaatgcgg cgaatttctt ccatccggtg gctgacataa atcaccgcca cgcccagtgc
    47581 cgacatcttt ttcaccgcgc tgatcaccag ttcaacttcc gcactggcaa gcgaactcgt
    47641 aggttcatca agaatgacca cgcgcggctc gcccttcatc acccgtgcaa tttccaccag
    47701 ttgcttttgc gccgggctta gcgttgaaac aagttgttca ggactaacgt caacgcccag
    47761 cgcctgtaag caacgttggg catcctgcgc catttgcagg taatcaatca tgccgttgcg
    47821 gcggggccac tgaccgaggc agaggttttc cgccaccgtc agcccttcca ccagacttaa
    47881 ctcctgataa accgcacgaa cccccagttc agcggcacgg cgagtcaacg tagcttcgtc
    47941 accttccagt cgcgtctcgc caatccagat atcaccgcta tccgggcgtt cactgccggt
    48001 aagcattcga atgagagtcg atttgcccgc gccgttttta cctaacagcg cacgaacttc
    48061 gcctttattg agcgtgaagt taacgttatc cagcgcaacg acgccggggt aacgcttatt
    48121 tcctgccacc acttttgcta ccgggactgc atctgttgcc gtgaacatag ggacctctgc
    48181 gaatcagcga ttagggcaga ccatcaacgt gcgttgccag ccactgttta ccatcttccg
    48241 ttttggtata gagatcgatt ggcacctgaa tcactttttc accgtcggct tgtttattga
    48301 taaccttcaa tgtttgcgcg agaacagcat tgcccatttt cttaccggaa atatccacta
    48361 ccgctttcag cacctgattg ttttccagct cctgagcaat ttcagtggtc atatccgaac
    48421 cgaaaacagc aatttttccg gcctgatttt gattacgtac cgcttttacc gcgccgagtg
    48481 tcgctccgcc cgattcaccc ataatggcgt tgagatccgg cgtggagata attagttttt
    48541 caccaacgga aatcgcttta tctaaaacag tcccttcctg attagcgaca atttgcgcgc
    48601 cgggaacgcg ggattttaat acttcttcaa atcctttacg tcgctgcaca caaacttcaa
    48661 aggcttcgca attgatgacg gcaattttcg gctggtcaat tttattggca ataaaataat
    48721 cggcggcagc attacccagt tttttaccaa attccagcgg atcgccgacc agatacgccg
    48781 agacatattt atcgacaccc ttttgattaa tacaggtgtt gtagcaaatc accggaatac
    48841 ccgcttcact ggcgcgacga acggtacggc tactgccatt ttcagacact gccgataaaa
    48901 taatggcatc gacattacgc gccacgaggg tatcaacaaa ggtactttct ttcgaaatat
    48961 caccctgggc gttagtttca attaactgta cctgtactga agaatctttt gccgcatcct
    49021 gaacgccttg acgcactcca gcgtaatatc cctgagtatc aaggtatatt gcgccaatgg
    49081 tcatttcttt ttccgcagcc ctggcaaata aagcgctacc taatagcgta gccattaata
    49141 atagattacg ggttgttctc atttttttag gcatagagcc tcctgtaggg tttttattaa
    49201 caacggctta ttctaattat tttgtgatga gcggcagcgc gtgccgctca aatattacag
    49261 ttaatagggt ttagtgaacg tagttaaaaa taaaaggcat cacagtggtg aataatgccg
    49321 ctttcggcca ggccggatta atcgccgtca attcagcgcg agcagactca tattgcgcaa
    49381 cctccccgag tcccgcggac gccagcatcg ccaccatcag gcatttttct ttatgctgct
    49441 gttgtaaatc gccatacagc gacaacagat caggttgtga aacagcaaag aaatccgcct
    49501 caatactggt tttcgccatc tcttgcgccc actgtttcat ttcactaaac agttgctgtg
    49561 cggtgtgttg ttcgcccagc agtcgcagcg ccattccttg ccagaagaga taatcaaccg
    49621 gctgatcgtt gtaataactg tggatgttaa tggtgcgatc gccggtcgcc gccagacgta
    49681 aacaacgcat cgcttcagtt tcatcgccct gcgcgttggc gcatatcgcc tgccagaacc
    49741 agatgtcgtt atcagtttgc cccggtaaac ggccttcgct taaattctcc ggataatgca
    49801 gcgcggcatg aagcagttcg ctggcctgct gcggctgtct ggcatcaagg tgctgccagg
    49861 cgcgtaataa ctggttgagg ataaactgac tggtgacctt cccttccccg ccttcccacg
    49921 ggtggaattt gcgcgtggcg agaatgtccg ccgctttgtc tgcctgaccc gtgagatgcc
    49981 acaaattgag caactctgct gtcatgtcgt cgcgtttcag cgcaatttcc agattatttt
    50041 ccagacgcgc cagtcgtttc tccggtgtgg ctccgcttaa cttatcaagc aaatcccgtt
    50101 cgaaaagcag acgtgcatcc tgcggcgcaa gctgataagc attatcaaga taacgcgcgg
    50161 ccagctcata atcgtgttgc ttattccacg catggatcgc taacccgcgc cagccgtcgg
    50221 caaactccgg cgacatctct acgcaacgtt gccataaagt aatggctttg ttgtagctgc
    50281 gcttgttgta gtagaagcag gccagtaaat gacgggcaaa ccagcactct tcaatactct
    50341 ccagcgccgc cacttcttcc agcgtattcg ggaaacggac aaactgcggg aagacatcaa
    50401 tggcttttgc gaccagttcg ccgcgttcgg ctttcggcag caagctggct tgtagataaa
    50461 gcgataacgt gcgctgacag tccagtgcgt tcagcatctc tgtcgccaga gtgggcattc
    50521 cccagttaat cagttgcccg gcggtcatca gggcgttaac gtcgcgtccc tgacacagac
    50581 cgcgccactg cgcgagagct gattcgctac gaccatcgaa ccagttcagc caccacagag
    50641 tggcgttcag cggataatcg cgcagcagtt tctcgcgctg cacacgcgcg ttgtcctgac
    50701 gaccacttaa caccagcagc agattatgca ggcaaagcac ttcctgattg gttgggcagg
    50761 cgcgaagact ttgttggcaa aaatccagac cagcgtcgaa gttaccatta cgcgccgcca
    50821 gtcgtgccag gccataatag ccaccggctt tgctgttgcc gctccagacc gcacgccaga
    50881 aatcctcttc ggcttgttga tattgtccct gacgttcgta agcactggcg cgaatcaaac
    50941 tcgcctgtcc gcactgcgga tttttgttca gcgcatgtgc gcgtttcaga gcctgagtgg
    51001 catacgccac cgcttgcggg aaatcggcac ggttatattc cagcatcgcc agcgccaggt
    51061 tacagcggta atccagcgga tccagcgcca cgccgcgcag gtagtaatcg aacggtgaac
    51121 ggctggcgtg atgatattgc tccagatgct gaccgataaa ccaggcttca tctgtactgg
    51181 taatgtcttg tgctgacagt ggcgctttgg cgacgtccgg caacggcaac tcttgcggct
    51241 gatgttcctg ataactcagt acaatattgc cgtcggcatc ggagagctca atggtcagcc
    51301 tttcaggatt gataccgtgc aacacgccct ggatggcggt cgcaggcatc agtgccacgg
    51361 catcatcaag taacgcgttg catttgccga tttcgcggat cgccaggcgg tatccgttca
    51421 acggagagat ggcatacagc ccccactcaa tcccccgctc actacgctgg agttttatca
    51481 ccgcatcgcg ggaggcattt tgcaccatgc ccaaagaatg ataaggcagg aaatactgct
    51541 caaaacgctt ctcttcgtaa gcatcaagcc aggtaaaatc aggctggtta tcggcaaaaa
    51601 taccggtcat cagttcgata tacgggccgt tattgtcggt cagactcttg tcccacgcct
    51661 ggccgaattc actgtgtccc cagctccact gttttttacc tggcgcgata tggtggttgg
    51721 caacgtgtag caaaccgcca tcttcatcgt gacaccacgc gccaacaaaa tcgtactgtg
    51781 atttttcagc catatatgag gttggaacgg gcacattttt atagcgagaa atgtccactc
    51841 cggcggagta gtccactttg tagtaagtgc cggtggcgat ggggaaagcg gagacggccc
    51901 gtttgccgtg atcaaacacc gccgttacat ccggcgggaa aacgctctga tgcccttccc
    51961 cccctttcac tgccgggttg gcccaccaca agaaatgacg cggcgtggcg ttgccgttat
    52021 agacgcggct ggcaatttcc aacgccgccc gttcaggacg cagtgtgaaa cctgtcatca
    52081 cctgtaaacc gtgcatcggc tccgtttcgc cgacccacac cgtctgtgcg ccgtcttcat
    52141 gggcttcgag ggtgaaatca acgggcataa aggtggtcgg gcgatggtgt tgcggccagt
    52201 taaactcaat cccgccagag atccacggtc ccagcagccc caccagcgca ggtttaatga
    52261 cttcattgtg atagacaaaa tcgcgttgtt tcactttatc ccatgcgcga tgcacacgac
    52321 cgcccagttc cggcaggatc atcactttga tgtagtcgtt ttccagccac accgcctgcc
    52381 aggatttcag ggttttctgc tcgctcagcg tatcggtcac gccgtaggga taaaccgcgc
    52441 cggacgatcc ctgataaacg cgattttcca ggaacatggg atgtatatcc tgcggcccgg
    52501 tttcataggt cgggatctca acgcgctctt gccacacttt tactggagtc atggtgccct
    52561 caatattaac aagacatact gaattaaaag atttgtggca gtgtattgaa caatctggca
    52621 atgttttcgc ggaataatca cgcaattaac taaacaaggt ttagtgaaga tgagagcctg
    52681 cattaacaat caacagattc gccaccataa caaatgcgtg attctggaac tgctgtaccg
    52741 gcaaaagcgc gccaataaat caacgctggc ccggctggcg caaatttcga ttccggcagt
    52801 cagtaatatt ttgcaggaac tggaaagcga aaaacgggtg gtgaatatcg acgatgaaag
    52861 ccagacgcgc gggcatagta gcggtacatg gctgattgcg ccggaaggtg actggacgct
    52921 gtgcctgaac gtgacgccca ccagtattga gtgtcaggtt gctaatgctt gtttaagtcc
    52981 gaaaggcgaa tttgagtatt tacagattga tgtaccgacg ccgcaggcgc tgctgtccga
    53041 aatcgaaaaa tgctggcatc gccaccgtaa attgtggccg gaccgcacca tcaatctggc
    53101 gctggcaatc cacggtcagg ttgatccagt gacaggagtg tcgcaaacca tgccgcaagc
    53161 gccgtggaca acgccggttg aggtgaagta tctgctggaa gagaagctgg gcattcgggt
    53221 gatggtcgat aatgactgcg tgatgctggc gctggcggaa aaatggcaaa ataattcgca
    53281 ggaacgggat ttctgcgtga tcaacgttga ttacggcatt ggctcgtcgt tcgtgattaa
    53341 cgagcaaatt tatcgcggca gtttgtatgg tagcggacag attggtcaca ccatcgttaa
    53401 tccggatggc gtcgtctgcg actgtggacg ttacggctgc ctggaaaccg tcgcctcgtt
    53461 aagcgcatta aaaaaacagg cgcgggtatg gctaaaatca caaccggtta atactcagct
    53521 tgatcctgaa aaattgacta ccgcgcagtt aatcgctgcc tggcagagtg gagaaccgtg
    53581 gatcaccagc tgggttgacc gcagtgccaa tgccattggt ttgagtctgt ataacttcct
    53641 caacatcctc aatattaatc agatttggtt gtacggtcgc agttgtgcct ttggtgagaa
    53701 ctggcttaat actattattc gccagacggg atttaacccg ttcgaccgcg acgaaggacc
    53761 gagcgtgaaa gcgacgcaaa ttggcttcgg gcaattaagc cgcgcacaac aggtgctggg
    53821 aattggctat ttgtatgttg aggcgcagtt acgacagatt tgatggcgcg ataacgtaga
    53881 aaggcttccc gaaggaagcc ttttttcaac agattaaccg tttcgcttat gcgtaaaccg
    53941 ggtaacgtgc gcagatgtcg agaactttac ctttgatgcg ctcgataacg gcttcatcat
    54001 tgatgctgtc cagcacgtca cacatccagc cagccagttc tttcgcttct gcttctttga
    54061 agccgcgacg cgtaattgcc ggagtaccca cgcgaatacc ggaggtcaca aacgggctct
    54121 tcggatcgtt cggtacgctg tttttgttga cggtgatgtt agcacggccc agagcggcgt
    54181 ctgcttcttt accggtcagg tttttatcaa ccagatcaac caggaacagg tggttatcag
    54241 tgccgccgga aaccactttg tagccgcgtt ccaggaacac ttctaccatc gctttagcgt
    54301 ttttagcgac ctgctgctgg taagttttga actcaggctc catcgcttct ttcagagcaa
    54361 ccgctttacc ggcgattacg tgcatcaacg gaccgccctg accaccaggg aaaacggcag
    54421 agttcagttt tttgtacagc tcttcgctac cacctttcgc caggatcagg ccgccgcgcg
    54481 gacccgccag ggttttgtga gtggtggtag taacaacgtg agcatgagga accgggttcg
    54541 ggtagacgcc agcagcaacc aggcccgcaa cgtgcgccat atcaacgaac aggtaagcac
    54601 cgatgctgtc agcgatttca cgcattttcg cccagtcaac cacgccggaa tatgcagaga
    54661 aaccaccgat aatcattttc ggcttgtgtt ctttggcttg tttttccaga tcggcgtagt
    54721 cgatatgacc ggtagcatcg ataccgtaag gaacgatgtt gtacagttta ccggagaagt
    54781 taaccggaga accgtgagtc aggtgaccgc catgcgccag gttcataccc agaacggtat
    54841 cacctggttc cagcagcgcg gtgtagaccg caaagttagc ctgggagccg gagtgcggct
    54901 ggacgttagc gtagtcagcg ccgaacagtt ctttcgcacg atcgatcgcc agttgttcaa
    54961 cgatatcaac atactcgcaa ccgccgtagt agcgtttgcc cggataacct tcagcatatt
    55021 tgttggtcag ctgagaaccc tgcgcctgca ttacgcgcgg gctggtgtag ttttcggagg
    55081 cgatcagttc gatgtgctct tcctgacgta ctttttcctg ctccatagcc tgccacagtt
    55141 cggcatcata atcggcaatg ttcatttcac gctttaacat ccgcatctcc tgactcagct
    55201 aacaataaaa tttttggcct ttataggcgg tcctgttgga caacggcgaa cagtataacc
    55261 gaatcattgt gcgataacag gtcttgacaa aggaatttac gcaaacgatt accttcaggc
    55321 tacgcaaggc tttggagaat aaagagcttg caaccggaaa cggatttctt ttcaggtttg
    55381 tgatgcaaat ttttcacttc atcacattct ttctgaaaaa caccaaagaa ccatttacat
    55441 tgcagggcta ttttttataa gatgcatttg agatacatca attaagatgc aaaaaaagga
    55501 agaccatatg cttgacgctc aaaccatcgc tacagtaaaa gccaccatcc ctttactggt
    55561 ggaaacgggg ccaaagttaa ccgcccattt ctacgaccgt atgtttactc ataacccaga
    55621 actcaaagaa atttttaaca tgagtaacca gcgtaatggc gatcaacgtg aagcactgtt
    55681 taacgctatt gccgcctacg ccagtaatat tgaaaacctg cctgcgctgc tgccagcggt
    55741 agaaaaaatc gcgcagaagc acaccagctt ccagatcaaa ccggaacagt acaacatcgt
    55801 cggtgaacac ctgttggcaa cgctggacga aatgttcagc ccggggcagg aagtgctgga
    55861 cgcgtggggt aaagcctatg gtgtactggc taatgtattt atcaatcgcg aggcggaaat
    55921 ctataacgaa aacgccagca aagccggtgg ttgggaaggt actcgcgatt tccgcattgt
    55981 ggctaaaaca ccgcgcagcg cgcttatcac cagcttcgaa ctggagccgg tcgacggtgg
    56041 cgcagtggca gaataccgtc cggggcaata tctcggcgtc tggctgaagc cggaaggttt
    56101 cccgcatcag gaaattcgtc agtactcttt gactcgcaaa ccggatggca aaggctatcg
    56161 tattgcggtg aaacgcgaag agggtgggca ggtatccaac tggttgcaca atcacgccaa
    56221 tgttggcgat gtcgtgaaac tggtcgctcc ggcaggtgat ttctttatgg ctgtcgcaga
    56281 tgacacacca gtgacgttaa tctctgccgg tgttggtcaa acgccaatgc tggcaatgct
    56341 cgacacgctg gcaaaagcag gccacacagc acaagtgaac tggttccatg cggcagaaaa
    56401 tggcgatgtt cacgcctttg ccgatgaagt taaggaactg gggcagtcac tgccgcgctt
    56461 taccgcgcac acctggtatc gtcagccgag cgaagccgat cgcgctaaag gtcagtttga
    56521 tagcgaaggt ctgatggatt tgagcaaaca ggaaggtgcg ttcagcgatc cgacaatgca
    56581 gttctatctc tgcggcccgg ttggcttcat gcagtttgcc gcgaaacagt tagtggatct
    56641 gggcgtgaag caggaaaaca ttcattacga atgctttggc ccgcataagg tgctgtgatt
    56701 tgatgttgcc ggatggaaac atccggcaac ccttgacgcg gtttaaattg ccgcgtcgtc
    56761 ctcttcaccg gtacggatgc gaatgacccg tgccacgtca aagacgaaga ttttaccgtc
    56821 accgattttg ccggtttgcg ccgtgcgaat aatggtatcg acacaggtat cgacaatgtc
    56881 gtccggtacg acaatctcaa ttttcacttt cggcagaaaa tccaccatat actccgcgcc
    56941 gcggtacagc tcggtatggc ctttctggcg accaaagcct ttcacttcgg tcaccgtcat
    57001 gccggtaata ccgacttcgg ccagtgcttc gcggacatcg tccagcttga agggttttat
    57061 aatcgcatca atctttttca tgctattcct tgaaaaggtc gcctgtcttt tgatctgcta
    57121 aacgtaacac ataacgccaa ttcattcctt gaaatcgttt gcatccagct cgtgtcggga
    57181 tagcagttta taaaattctg tccggttgcg ccccgccatt ctcgccgcgt gggtgacgtt
    57241 gcctttggta atttgcagca gcttacgcaa atagttgagt tcaaactgat tacgtgcctc
    57301 aacaaaggtt ggcagcgccg tattttcacc ctccagcgcc tgctctacta atgcatcgct
    57361 aataaccgga gatgaggtca gcgctacgca ctgttcaatc acgttgacca actggcgcac
    57421 attacccggc cagctagcgg tcatcaggcg tttcatcgca tcagtggaga acgcgcggac
    57481 aaacggttta tgtcgctctg ccgcctggcg caacaggtga tttgccagaa gcggaatgtc
    57541 ttctgtgcgc tctgccagag ccggaatttt caggctgaca acgttgaggc ggtaatagag
    57601 atcttcacgg aattccccgc gcgccatcgc ttttggcagg tcgcggtgag tggcggaaat
    57661 aatccgcacg tcgatatcaa tatcgcggtt gctgcccagc gggcgcactt tacgctcctg
    57721 caacacgcgc agcagtttga cctgcaatgg tgcgggcata tcgccaatct catcgagaaa
    57781 tagcgtaccg ccttccgccg cctggaataa accttcgcga ttgctgacag cgccagtaaa
    57841 cgcgccacgc gcatgaccaa acagctccga ctccagcaac tgctcgggca atgcgccaca
    57901 gttaatagca ataaatggtt tgctgttacg cgggctggcg ttgtggatag cctgggcgaa
    57961 aatctctttc ccggtgccgc tctggccatt aatcaacacg ctgacgtctg attgcgccac
    58021 cagccgcgcc tgttccagca aacgcagcat cagcgggctg cgggtgacaa ttgcctcgcg
    58081 ccagcgttca tcggtggctg gcgcggattg ctccagcgca tcgtcaattg cctgatatag
    58141 cgcgtctttg tcgacaggct tggtgaggaa actaaaaacg ccctgctgtg ttgcagcaac
    58201 ggcatcgggg atagaaccat gcgcagtaag aataattacc ggcattcccg gctgcacttt
    58261 ctggatttca gcaaacagct gcataccgtc catttcatcc atccgcaggt cgctgataac
    58321 taaatctact ttttcgcgat tcagtacccg taatccttca gcgccacttt ccgccgtgac
    58381 cacactgtag ccttcgctgg tcaggcgcag gccaagcagt ttcagcaatc ccggatcgtc
    58441 atcgaccaat aataaatgcg caggtttatg gctcatcagg agtgacctca tgggtggatg
    58501 gcgcgggctt ttcactctcg tgcggcgtat ccggcgagaa atttccagcc ggtttgcggg
    58561 tcgagagctg gcgttcaata tcggtcaggt tttccagctt gcgggtggtg agttccagtt
    58621 gctgctgtag aacgtgatgt tgctggcgca atgtatccag ctcgctgtcg ctggactgct
    58681 ggagtttact gtaacgttgg cgctcttccg ccagttgcag ttgcagcgcc tgaccgtcgc
    58741 gccagagttg atacagtggg cgaacctgtg ccgggatctc ggtacttaac gcttcaatac
    58801 gcgcgaccag ctggcggcgc tcatacggcg taattttggc gtcggcgagc aaaatccctt
    58861 gtttaaaggt attttgccag ctgccgtcgt catattggcg agcttgctga cgcgactgcg
    58921 caggcattaa acgatcagca caatccatcg cccgcagcca gtaaagcgga ttggtttcgg
    58981 ttgatttacc ttgcagcgcc cagatgtcgc tacattcagt agaaagatag tcagccagtt
    59041 gataaaccgg aattttttct tctgctggcg tatcaatggc tggcttattg tgattctgca
    59101 cgcaacccag caatgccaga catggcagcc ctgccagcca cagccgtcgg ggcaataatc
    59161 gttgaaaaat gtgtcgcata ttcaccagac ttaaagccta tcccagtggg cgtaattgtt
    59221 gcagacagtc tggacatgga cagcgcggag aaaccggagc gtacatatcg tacgtgaaga
    59281 tttcgagcac tgcccggggc cgaactgaca aataaaatag cctataggat aggctgttag
    59341 cattatttcg tgtttttcga cgacggtaat tcaatgcgga aacaaacgtc ttgcccgctc
    59401 tcgtcgacca gatacagttc cccttgcata cggcgaatac aatccctggc aatgcttaat
    59461 cccagaccgc tgcccttcac cgcccctttt cgctggtggc ttccctgaaa aaagggttcg
    59521 aagatcatgg cgcgttcctc ttgcggaatt ggcgtgccgg tattgatgac atcaatataa
    59581 acccgcgcac catgtgaact gctgcgaagg caaatgttac cggattcagc cccgtagtgc
    59641 accgcattgg agtaaagatt atccagtacg ctcatcagca gcattggctc cgccaggcaa
    59701 gctgttgctt tgagatcgac gtcggtatgc atcattttag cccgtgcggg caggctatga
    59761 gcagaaacca ctgtctccac cagcggtgct aattcaacat tctccagttc caccgcactg
    59821 tccgcctgtt tacggttgta atcaagcagt tgttcgatca gtttttgcaa attgcggctg
    59881 ctgctatcaa gaatgctcac cacctctttt tgctctggcg taagcggccc gacaacctgg
    59941 tcagccagta attcagtgcc ctcgcgcata ctcgccagtg gcgtttttaa ttcatgagat
    60001 aaatgtctta aaaattgatg gcgttgggat tccagccatg acaggcgctc acttaaccaa
    60061 agaatacgtt gcccaaccga gcgtaactcg ctcggtccac tgaacgaaac gctattgccc
    60121 agagaacgcc cttcccccag acggttgatc atgcgctcga tatttttcac cggcccgata
    60181 atcatccgcg tgaaaagtag caccatcacc agactcacca gaaatagcac cagcgattgc
    60241 caaccaaaat attgcccacg ttcggcgatt tcacgctgaa gttgctgccc acgagagaac
    60301 accactgtgc gcgtggcctg caccatttcg gtattggcac tggcaaaggc ttcaagacgc
    60361 gcggcggcgg cagcatcggg accactgttg ttacactgaa gttgggccag attgttcaaa
    60421 tcctgacgca atgcctggta aagtttatcg tctggcagtt cgcctgcgtg ggcatcgagc
    60481 atttcgctgt aacgcttgcg ctggctttga taaaccttcg caagcgtagg gtcgtccagc
    60541 acgcaatact gacggtagct acgctccatc tccagcgccg cgttggtcat cgcttcacta
    60601 cgccgggcat caataagcgt agtgcggtta accagcgccg cctgatcgct aagcgcattc
    60661 aggctttgcc aggcttgcca tgccagcacc aacaggggta gtagaattag caaaaatgcc
    60721 agcattacca gttgtcgtaa tgagcgggga aaaacgggcc agcgtttcaa ggtgttactc
    60781 tcgtcagacg cgaatagcct gatgctaacc gaggggaagt tcagatacaa caaagccggg
    60841 aattacccgg ctttgttatg gaataaggcg gtgcctaact cgacgtttcg cccgatggtt
    60901 gatatagcta cgctgatatc agaagttgga cggcaggcac cttgttgtgc gtcattcgaa
    60961 ttttatgtag cacgtcccga aggggctgac ataagtcggt gaatgagcca ctgcttacta
    61021 ttatgcagta actgtgccaa taaagaaaat agtttggtaa cgtactgatt atacgttgct
    61081 ttgagggatt tatggcttct tcgctatttg aatgtaaatc agccactgtg tcgctaaaaa
    61141 gagacaactt aagataaact tattagatta caataaaatc aatcatttaa gtgtcgccag
    61201 aaagcgacac ggtaaaccac ccattgtcgt gatttacaga cacaaaaaag ctcccggagt
    61261 tgggagctta tgatagtggt tggtgcttaa tgccggatgc ggcgtaaatg ccgcatccgg
    61321 gctgcaaaac caatgaactg atgacttacc ccaactgctt acgcgcattg cggaaaatgc
    61381 gcatccatgg gccatcctcg ccccagtttt ccggatgcca ggagttgctg acagtacgga
    61441 aaacacgttc cgggtgcggc atcataatgg tgactcgacc actttcagtc gtaaccgacg
    61501 taataccgtt cggagaaccg ttcgggttag ccgggtaggt ttcagtgact ttgccgaagt
    61561 tatcgacata gcgcagtgcc accagccctt tgctttccag tgccgccaga tgcgccgcat
    61621 cacgcacttc cacgcgccct tcaccatgag agacagcaat cggcatttgc gagcccacca
    61681 tcccctgcaa cagcagagac gggctttggg tcacttcaac caggctgaaa cgcgcttcaa
    61741 agcgatcgga ggtattgcgc acaaaacgtg gccacaactc gctccccggg atcagttcac
    61801 gcaggttaga catcatctgg caaccgttac atacccccag cgccagcgtt tgcggacggt
    61861 ggaagaaggt tgcaaactca tcgcgtacac ggtcattgaa caggattgac ttcgcccaac
    61921 cttcaccggc acccagcaca tcaccgtagg agaaaccacc gcacgcgacc agggcgtgga
    61981 aatcttccag gcccgtgcgt ccagccagca ggtcgctcat atgcacatcg attgcatcga
    62041 agcctgcacg gtggaaggct gccgccattt caacatgtga gttcacaccc tgctcacgca
    62101 gcacggcaac tttcggacgt gcgccagtgg caatatacgg tgctgccaca tcttcgttga
    62161 tatcgaacga cagtttcaca ttcaggcccg gatcggcgtc gtttgatttc gcctggtgct
    62221 cctgatcggc acactccggg ttgtcacgca ggcgctgcat ctgccaggta gtttctgccc
    62281 accagacacg caacgtagtg cggctttcgc tgaatacagt ctgcccgttg gcggtaatca
    62341 caaaacggtt accgaaaacc gcctgcccta cataatggac gcaatccgca agcccatgct
    62401 gtgccagtac ggactcgacc gcttcacggt cagcggcacg aacctgaatc accgcaccca
    62461 gttcttcgtt aaacaacgcc gccaggcgat cgtcgcccag agaggcaata tccgcgttaa
    62521 tgccgcaatg accagcaaag gccatttccg ccagcgttac cagcaggccg ccatcagagc
    62581 ggtcgtggta tgcgagcagc ttacgctgtg caaccagcgc ctgaatcgcg tcatagaagc
    62641 ctttcagttg cgcgacgttg cgtacatctg ccggtttgtc gccaagctga cgataaacct
    62701 gcgccagcgc cgttgcgccc agcgcgttat tgcctttgcc caaatcaatc agcagcagtg
    62761 cgttatcttc ggtagaaagc tgcggcgtga tggtgtgacg tacatcttcc acgcgggcaa
    62821 atgcagaaat caccagcgac agcggcgacg tcatttcgcg ctcttcgtta ccttcctgcc
    62881 agcgggtttt catcgacata gagtctttac ccaccgggat cgtcaggccc agcgccggac
    62941 aaagctcttc gcccacggct ttaacggctt catacaggcc cgcatcttca ccagggtggc
    63001 ctgccgccgc catccagttg gcggaaagtt taatgcgttt gatatcgcca atctgtgttg
    63061 cggcaatatt ggttaacgct tcaccgaccg ccagacgggc agaggcggcg aaatccagca
    63121 gcgcaaccgg cgcacgctcg ccaatcgcca tcgcttcacc gtagtagctg tcgaggctgg
    63181 cggtagtgac cgcgcagtta gcgaccggca cctgccacgg acccaccatc tgatcgcgcg
    63241 ccaccatgcc ggttacgctg cggtcaccga tggtcaccag gaaagttttc tccgccacgg
    63301 tcggcagatg cagtacgcgt ttcaccgcgt ctgcaatggt gatcccttca cggaccagcg
    63361 catcgccctt cgctttcagc gtttgtacat cgcgggtcat cttcggcgtt ttaccaagca
    63421 ggacgtccag cggcagatcg atcggctgat tatcaaaatg acgatcgtgc agagaaagat
    63481 gcagttcttc ggtcgcttca ccaatcaccg cgtagggcgc gcgttcacgc ttacacagtt
    63541 cgtcaaacag cggtaactga tcggcagcaa ccgccagcac gtagcgttcc tgggattcgt
    63601 tacaccagat ttccagcggg ctcatgcccg gttcgtcgtt cagaatatcg cgcagttcga
    63661 atttaccgcc gcgtccgccg tcgctcacca gttccggcat cgcgttagaa agaccgcctg
    63721 cgccgacgtc gtggataaac agaattgggt tagcatcacc aagctgccag caacggtcga
    63781 tcacttcctg gcagcgacgc tccatctccg ggttgtcgcg ctgaacagaa gcaaagtcga
    63841 ggtcggcatc agactgacca gacgccatag aagacgccgc gccgccgcca agaccgatgt
    63901 tcatcgccgg gccgccgaga acgaccagtt tcgcaccaac gttgatctcg cctttttgta
    63961 cgtgatcggc acgaatgttg ccgatcccgc ccgccagcat gatcggtttg tgataaccgc
    64021 gcagctcttc gccgttgtgg ctgttcactt tttcttcata agtacggaag tagccgttca
    64081 gtgccggacg accaaattcg ttgttaaacg ccgcaccgcc cagcgggcct tcggtcatga
    64141 tgtccagcgc ggtgacaatg cgctcaggct taccgaaatc ttcttcccac ggctgttcga
    64201 agccaggaat tcgcaggttg gaaacggaga aaccaaccaa acccgctttc ggcttcgcgc
    64261 cgcgcccggt ggcaccttca tcgcggattt caccgccgga accggtcgcc gcgcccggcc
    64321 acggagaaat cgccgtcggg tggttgtgag tttcgacttt catcagaata tgcgccggtt
    64381 cctgatggaa atcgtagcgg cccgtttcgt ggtcagcaaa gtagcggccc acttcagaac
    64441 cttccattac ggcggcgtta tctttataag cagagagaac gtgatctggc gtggtttcga
    64501 aagtattttt gatcatcctg aacagcgatt tcggctgttg ttcaccgtcg ataatccagt
    64561 cggcgttaaa aattttgtgg cggcagtgct cagagttcgc ctgagcgaac atatacagct
    64621 cgatgtcgtt cgggttacga ccaagctttg tgaaagcatc ctgcagatag tcaatttcat
    64681 cttccgccag agccaggcca agacgcaggt tagcgtcgat cagcgcctga cggccctgcc
    64741 ccagcaaatc aacgcttgtg accggagtcg gttgatggtg ggcaaacaac tgctctgcat
    64801 catctaaatc aaaaaagacc gtttccatca tgcggtcgtg cagttcagcg gtaacctgct
    64861 gccattgttc attggtcagc gtaccggctt ctatatagta agcaacgccg cgctcaaggc
    64921 ggtttacctg ttgtagcccg cagttatggg caatatcggt cgctttcgaa gaccagggag
    64981 agatggtgcc aggacgcggg gtcaccagca ggagtttgcc ttgcggggcg tggctggcga
    65041 gtgccggacc atatttcagc aggcgttcaa gttgtgcgtg ctcatcatcg tttaacggcg
    65101 cattgaggtc agcaaaatgg acatactcgg cgtaaatatt gtgaaccggg agcctggcag
    65161 cctgaaaacg tgccagcagt ttgttgattc ggaatgccga cagtgcaggc gaaccacgca
    65221 gaatttccat cataagtctc tcgtcttcta agctttcggt gtacccaagg gggggaaacg
    65281 ggcgtcatta taaagaatct gatgcgctga cgaaaccgtt tgcgtggaaa taaaatcacc
    65341 atcgtgaatt agcaacgcgt gccgccaatg gctgtaataa gttgccatct ggcgcaggtt
    65401 tacgcaaaat gccgctcatt tatgagtaaa cctttcacta ttattacgtt ttttcaagct
    65461 gggacgcgca cgacacagag aattaactaa ttgaaaaaat taaagattaa ttatctgttc
    65521 atcggcattc tggcactgct gctcgcggtc gctctctggc catccattcc ctggtttggt
    65581 aaagccgaca accgtatcgc cgccattcaa gcgcggggag agttgcgtgt gagcaccatt
    65641 catactcccc tgacttataa cgaaatcaac gggaaacctt ttggcctgga ttacgaactg
    65701 gcgaaacagt ttgccgatta cctcggtgta aaactgaaag tgaccgtgcg gcagaatatc
    65761 agccagctgt ttgacgacct cgataatggt aacgccgacc tgctggcggc aggactggtc
    65821 tataacagtg agcgggtaaa aaattatcag cctggcccta cctattattc cgtgtcacaa
    65881 caactggttt ataaagtggg tcagtatcgc ccgcgcacac tgggcaacct gacggcggag
    65941 caactcaccg ttgcaccggg tcacgtggtg gttaacgatc tccaaaccct gaaagacaca
    66001 aaattcccgg aattaagctg gaaggtagac gacaaaaaag gctctgcgga attaatggaa
    66061 gatgtcatcg aaggaaaact cgattacacc attgctgatt ctgtcgccat cagcctgttt
    66121 cagcgcgttc acccggagct cgccgtagcg ctcgatatca ccgatgaaca accggtgacc
    66181 tggtttagcc cgttagatgg cgataatacc ctttccgccg ccctgctcga cttcttcaac
    66241 gaaatgaatg aagacggtac gctggcacgc attgaagaga aatacctggg gcatggcgat
    66301 gattttgatt acgtcgatac gcgcacattt ttacgcgccg tcgatgcggt actgccgcag
    66361 ttaaagcccc tgtttgagaa atacgccgaa gaaattgact ggcgtttgct ggccgctatt
    66421 gcttatcagg aatcgcactg ggatgcacag gccacttcac cgacgggtgt gcgcggcatg
    66481 atgatgttaa ccaaaaatac cgcgcaaagc ctcggcatta cggatcgtac cgatgccgaa
    66541 cagagcatca gcggtggcgt gcgttatttg caggatatga tgagtaaagt gccggaaagt
    66601 gtgccggaga acgagcggat ctggtttgcc ctcgctgcgt acaatatggg ctatgcgcat
    66661 atgctggatg cccgcgccct gacggcaaaa accaaaggga atcctgacag ttgggctgac
    66721 gtaaaacagc gtctgccttt acttagccag aaaccctatt acagcaagct gacttacggc
    66781 tacgctcgtg gacatgaagc ctacgcttat gtcgaaaata ttcgtaagta tcagattagc
    66841 ctggtgggtt atctgcaaga gaaagagaag caggctacag aagcggcgat gcaactggcg
    66901 caggattatc cggcggtatc gcctacggag ttgggcaaag agaaatttcc ttttctctcg
    66961 tttctttccc agtcgtcatc aaactatttg acccattctc cctctctgct gttttccagg
    67021 aaagggagtg aagagaaaca aaattaatcc gtcgaggatt gcgctttttt ctgcgcttta
    67081 atttcctggc ggcgcatgcg aaagaagtca ctgagcaacg ctgcgcactc atccgccagt
    67141 attccttccg taatttccac tcggtgattc atacccggat gatgcagcac atccattaaa
    67201 gatcccgcag cgccagtttt cgcgtcatgc gcaccaaaga ccacgcgacc aatgcgactg
    67261 tggatcatcg ctccggcaca cattacacat ggttcaagcg tgacatacaa cgtggcgtcg
    67321 atcagacgat aattttgcat caccagacca ccctgccgca gggccatgat ttctgcatgt
    67381 gcggtgggat catggcgacc aatcgggcgg ttccagcctt cgccgattac ccgattgtta
    67441 tgcactaata ccgcgccgac cggcacttcc cgctcatccc aggcacgttt cgccagcgtc
    67501 agcgcgtgac gcatccagta ttcgtggcta aattcgactt cagacaaaaa gaaaactccg
    67561 gttataaaag cgcggcgcat tatacacgga cgctatgctt tactctattc cagttgctgg
    67621 agttcaccgc gcggggttac tcgccaacga tgctgacaga aataaagcag cggattgtcc
    67681 tgattactgt cgctatagcc actgtacagc cgcagcggag tgccgatttt gcgctccagt
    67741 tgtgcgacct tttcatgtcc cagacaacgc atcgtcaata cccaaccacc atagccacgc
    67801 tgaatttggc tggcgataag attaacccgc ggcagccagg gcgtatcgaa ataaaccgct
    67861 tcaaccagcg gctgcggaga gccggtaatc aaccagatat cagcatcgga acttaacagg
    67921 taggtggtta atcgctcctg aaccagcgga aaggcggtaa cattgtcgcg aaaccagcgc
    67981 acgaaatcgg cctgcaacgt ctgtaaacgt gcttcgctgt gaccaaaagt gcacccccac
    68041 agaagcagac tcatcggcca gcgtgccgca cgacctttta tcaataacgc aatggctata
    68101 atcggtaaca acggcaggac aagtaacgca ttcagcggtt ggcgacgcag taaatagcgc
    68161 agaaaactgc cgaacatatc ctgctgatgc aatgttccat ctaagtcaaa aaacaccaca
    68221 cgacgctcgt gagttgccaa accatactcc tctggactga aacatcctga ttaattttcg
    68281 ctactacata gcctaacaga tagatcatca cttttccggc aacaatcgac cgcatcatgg
    68341 ctaactggaa tttttaattc atggcaatta gcggcaatgg aatataaaat tcactcgcgt
    68401 gtgtctcata ttgcctgttg tcgccactat ttcatcgcga ggaaagatat gaacggctta
    68461 cttcgtatcc gtcagcgtta ccaggggctt gcccagagtg ataaaaaact ggcggattat
    68521 ctgctgctac aacctgatac ggcgcgccat ttaagttctc agcaactggc caacgaagcc
    68581 ggagtcagtc agtccagcgt cgtgaagttc gcgcaaaaac tcggctataa aggttttccg
    68641 gcgcttaagt tggcgttgag tgaagcgctg gcaagccagc cggaatcgcc ctccgtgccc
    68701 attcataacc aaatccgcgg tgatgatccg ttacggctgg tcggcgaaaa actgattaaa
    68761 gaaaatactg ccgctatgta cgcaacgcta aacgttaata gtgaagagaa actgcatgaa
    68821 tgcgtaacaa tgttgcgctc tgcgcggcgg ataattctga ccggtattgg cgcttcgggt
    68881 ctggtggcgc aaaactttgc ctggaagctg atgaagattg gcttcaatgc tgccgcagtg
    68941 cgcgatatgc atgcgctact cgcaacagta caggcgtcgt cccctgacga tctgttatta
    69001 gccatttcct acaccggtgt acgacgcgag ttaaacctgg cggcagatga gatgctgcga
    69061 gtgggcggaa aagtgctggc gattaccggc tttactccca atgccctgca acagcgtgct
    69121 tctcattgcc tgtataccat tgccgaagaa caagcgacaa acagtgcttc aatctctgct
    69181 tgtcacgctc agggaatgtt aacggatttg ctgttcattg cgctgattca gcaggatctg
    69241 gaactggcac cagaacgtat tcgtcagagt gaagcgctga tgaaaaaact ggtctgagta
    69301 aagaatgcgc gtataatgcc cgcccggttt gtgttgtttt gagagtttcc ttatggcgtt
    69361 gttaatcact aaaaaatgca tcaattgtga tatgtgtgaa cccgaatgcc cgaatgaggc
    69421 gatttcaatg ggagatcata tctacgagat taacagcgat aagtgtaccg aatgcgtagg
    69481 gcactacgag acaccaacct gccagaaggt gtgcccgatc cccaatacta ttgtgaaaga
    69541 tccggcgcat gtcgagacag aagaacagtt gtgggataaa tttgtgctga tgcaccacgc
    69601 ggataaaatt taatattcta c
//
LOCUS       DAPOAV010000011        67573 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.011, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000011 DAPOAV010000000
VERSION     DAPOAV010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 67573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67573
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.011"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            168..503
                     /gene="eutS"
                     /locus_tag="RN951_000877"
     CDS             168..503
                     /gene="eutS"
                     /locus_tag="RN951_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutS"
                     /protein_id="HDX2525925.1"
                     /translation="MDKERIIQEFVPGKQVTLAHLIAHPGEELAKKIGVPDAGAIGIM
                     TLTPGETAMIAGDLALKAADVHIGFLDRFSGALVIYGSVGAVEEALSQTVSGLGRLLN
                     YTLCEMTKS"
     gene            516..995
                     /gene="eutP"
                     /locus_tag="RN951_000878"
     CDS             516..995
                     /gene="eutP"
                     /locus_tag="RN951_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutP"
                     /protein_id="HDX2525926.1"
                     /translation="MKRIAFVGSVGAGKTTLFNALQGNYTLARKTQAVEFNDKGDIDT
                     PGEYFSHPRWYHALITTLQDVDMLIYVHGANDPESRLPAGLLDIGVSKRQIAVISKTD
                     MPDADVAATRKLLLETGFEEPIFELNSHDPQSVQQLVDYLASLTKQEEAGEKTHHSE"
     gene            970..1671
                     /gene="eutQ"
                     /locus_tag="RN951_000879"
     CDS             970..1671
                     /gene="eutQ"
                     /locus_tag="RN951_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutQ"
                     /protein_id="HDX2525927.1"
                     /translation="MKKLITANDIREAHARGEQAMSVVLRASIITPEAREVADLLGFT
                     ITECDESIPVTASVPASVPADKTESQRIRETIIAQLPEGQFTESLVAQLMEKVMKEKQ
                     SLEQGAMQPSFKSVTGKGGIKVIDGSSVKFGRFDGAEPHCVGLTDLVTGDDGSSMAAG
                     FMQWENAFFPWTLNYDEIDMVLEGELHVRHEGQTMIAKAGDVMFIPKGSSIEFGTTSS
                     VKFLYVAWPANWQSL"
     gene            1668..2471
                     /gene="eutT"
                     /locus_tag="RN951_000880"
     CDS             1668..2471
                     /gene="eutT"
                     /locus_tag="RN951_000880"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization cob(I)yrinic acid
                     a,c-diamide adenosyltransferase EutT"
                     /protein_id="HDX2525928.1"
                     /translation="MKDFITEAWLRANHTLSEGAEIHLPADSRLTPSARELLESRHLR
                     IKFIDEQGRLFVDDEQQQPQPVHGLTSSDEHPQACCELCRQPVAKKPDTLTHLSAEKM
                     VAKSDPRLGFRAVLDSTIALAVWLQIELAEPWQPWLADIRSRLGNIMRADALGEPLGC
                     QAIVGLSDEDLHRLSHQPLRYLDHDHLVPEASHGRDAALLNLLRTKVRETETVAAQVF
                     ITRSFEVLRPDILQALNRLSSTVYVMMILSVTKQPLTVKQIQQRLGETQ"
     gene            2468..3484
                     /gene="pta"
                     /locus_tag="RN951_000881"
     CDS             2468..3484
                     /gene="pta"
                     /locus_tag="RN951_000881"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HDX2525929.1"
                     /translation="MIIERCRELALRAPARVVFPDALDQRVLKAAQYLHQQGLATPIL
                     VANPFELRQFALSHGVAMDGLQVIDPHGNLAMREEFAHRWLARAGEKTPPDALEKLTD
                     PLMFAAAMVSAGKADVCIAGNLSSTANVLRAGLRIIGLQPGCKTLSSIFLMLPQYSGP
                     ALGFADCSVVPQPTAAQLADIALASAETWRAITGEEPRVAMLSFSSNGSARHPCVANV
                     QQATEIVRERAPKLVVDGELQFDAAFVPEVAAQKAPASPLQGKANVMVFPSLEAGNIG
                     YKIAQRLGGYRAVGPLIQGLAAPMHDLSRGCSVQEIIELALVAAVPRQTEVNRESSLQ
                     TLVE"
     gene            3523..3816
                     /gene="eutM"
                     /locus_tag="RN951_000882"
     CDS             3523..3816
                     /gene="eutM"
                     /locus_tag="RN951_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HDX2525930.1"
                     /translation="MEALGMIETRGLVALIEASDAMVKAARVKLVGVKQIGGGLCTAM
                     VRGDVAACKAATDAGAAAAQRIGELVSVHVIPRPHGDLEEVFPIGLKGDSSNL"
     gene            3923..4210
                     /gene="eutN"
                     /locus_tag="RN951_000883"
     CDS             3923..4210
                     /gene="eutN"
                     /locus_tag="RN951_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutN"
                     /protein_id="HDX2525931.1"
                     /translation="MKLAVVTGQIVCTVRHHGLAHDKLLMVEMIDPQGNPDGQCAVAI
                     DNIGAGTGEWVLLVSGSSARQAHKSETSPVDLCVIGIVDEVVSGGQVIFHK"
     gene            4222..5625
                     /locus_tag="RN951_000884"
     CDS             4222..5625
                     /locus_tag="RN951_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase EutE"
                     /protein_id="HDX2525932.1"
                     /translation="MNQQDIEQVVKAVLLKMQSSDTPPAAVHEMGVFASLDDAVAAAK
                     VAQQGLKSVAMRQLAIAAIREAGEKHARDLAELAVSETGMGRVEDKFAKNVAQARGTP
                     GVECLSPQVLTGDNGLTLIENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVIFAP
                     HPAAKKVSQRAITLLNQAIVAAGGPENLLVTVANPDIETAQRLFKFPGIGLLVVTGGE
                     AVVEAARKHTNKRLIAAGAGNPPVVVDETADLARAAQSIVKGASFDNNIICADEKVLI
                     VVDSVADELMRLMEGQHAVKLTAEQAQQLQPVLLKNIDERGKGTVSRDWVGRDAAKIA
                     AAIGLNVPQETRLLFVETTAEHPFAVTELMMPVLPVVRVANVADAIALAVKLEGGCHH
                     TAAMHSRNIENMNQMANAIDTSIFVKNGPCIAGLGLGGEGWTTMTITTPTGEGVTSAR
                     TFVRLRRCVLVDAFRIV"
     gene            5636..6472
                     /gene="eutJ"
                     /locus_tag="RN951_000885"
     CDS             5636..6472
                     /gene="eutJ"
                     /locus_tag="RN951_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutJ"
                     /protein_id="HDX2525933.1"
                     /translation="MAHDEQWLTPRLQTAATLCNQTPAATESPLWLGVDLGTCDVVSM
                     VVDRDGQPVAVCLDWADVVRDGIVWDFFGAVTIVRRHLDTLEQQFGLRFSHAATSFPP
                     GTDPRISINVLESAGLEVSHVLDEPTAVADLLQLDNAGVVDIGGGTTGIAIVKKGKVT
                     YSADEATGGHHISLTLAGNRRISLEEAEQYKRGHGDEIWPAVKPVYEKMADIVARHIE
                     GQGITDLWLAGGSCMQPGVAELFRKQFPALQVHLPQHSLFMTPLAIASSGREKAEGLY
                     AK"
     gene            6462..7649
                     /gene="eutG"
                     /locus_tag="RN951_000886"
     CDS             6462..7649
                     /gene="eutG"
                     /locus_tag="RN951_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization ethanol dehydrogenase
                     EutG"
                     /protein_id="HDX2525934.1"
                     /translation="MQNELQTALFQAFDTLNLQRVKTFSVPPVTLCGPGSVSSCGQQA
                     QTRGLKHLFVMADSFLHQAGMTAGLTRSLAVKGIAMTLWLCPVGEPCITDVCAAVAQL
                     RESGCDGVIAFGGGSVLDAAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGT
                     GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAALTEGVPSHVTAMTGIDALTHAI
                     EAYSALNATPFTDSLAIGAIAMIGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAG
                     LGLCHAMAHQPGAALHIPHGLANAMLLPTVMEFNRMVCRERFSQIGRALRTKKSDDHD
                     AINAVSELIAEVGIGKRLGDVGATSAHYGAWAQAAQEDICLRSNPRTASLEQIVGLYA
                     AAQ"
     gene            7766..8992
                     /gene="eutH"
                     /locus_tag="RN951_000887"
     CDS             7766..8992
                     /gene="eutH"
                     /locus_tag="RN951_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HDX2525935.1"
                     /translation="MGINEIIMYIMMFFMLIAAVDRILSQFGGSARFLGKFGKSIEGS
                     GGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVIIPVYEMLGANPSMFAGTLLACD
                     MGGFFLAKELAGGDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLA
                     GIVTIPIGCIAGGLVAMYSGVQINGQPVEFTFALILMNMIPVIIVAILVALGLKFIPE
                     KMINGFQIFAKFLVALITLGLAAAVVKFLLGWELIPGLDPIFMAPGDKPGEVMRAIEV
                     IGSISCVLLGAYPMVLLLTRWFEKPLMSVGKVLNMNNIAAAGMVATLANNIPMFGMMK
                     QMDTRGKVINCAFAVSAAFALGDHLGFAAANMNAMIFPMIVGKLLGGVTAIGVAMMLV
                     PKEDATATKTEAEAQS"
     gene            8989..10392
                     /gene="eutA"
                     /locus_tag="RN951_000888"
     CDS             8989..10392
                     /gene="eutA"
                     /locus_tag="RN951_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HDX2525936.1"
                     /translation="MNTRQLLSVGIDIGTTTTQVIFSHLELVNRAAVSQVPRYEFIKR
                     EISWQSPVFFTPVDKQGGLKEAELKSLILEQYQAAGIAPESVDSGAIIITGESAKTRN
                     ARPAVMALSQSLGDFVVASAGPHLESVIAGHGAGAQTLSEQRLCRVLNIDIGGGTANY
                     ALFDAGKISGTACLNVGGRLLETDSQGRVVYAHKPGQMIVDECFGAGTDARSLTGAQL
                     VQVTRRMAALIVEVIDGTLSPLAQALMQTGLLPAGVTPEIITLSGGVGECYRHQPADP
                     FCFADIGPLLATALHDHPRLREMNVQFPAQTVRATVIGAGAHTLSLSGSTIWLEGVQL
                     PLRNLPVAIPIDETDLVSAWQQALIQLDLDPKTDAYVLALPASLPVRYAAVLTVINAL
                     VDFVARFPNPHPLLVVAGQDFGKALGMLLRPQLQQLPLAVIDEVIVRAGDYIDIGTPL
                     FGGSVVPVTVKSLAFPS"
     gene            10404..11765
                     /gene="eutB"
                     /locus_tag="RN951_000889"
     CDS             10404..11765
                     /gene="eutB"
                     /locus_tag="RN951_000889"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit alpha"
                     /protein_id="HDX2525937.1"
                     /translation="MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQER
                     VAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLS
                     DETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSAR
                     LQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNI
                     PTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFN
                     RIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEY
                     LYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIM
                     GMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPS
                     LFF"
     gene            11786..12673
                     /gene="eutC"
                     /locus_tag="RN951_000890"
     CDS             11786..12673
                     /gene="eutC"
                     /locus_tag="RN951_000890"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit beta"
                     /protein_id="HDX2525938.1"
                     /translation="MDQKQIEEIVRSVMASMGQTAPAPSEAKCATTNCAAPVTSESCA
                     LDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRS
                     KDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPD
                     VQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILG
                     AKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVI
                     VDLAKRMLEQKASGINMTR"
     gene            12683..13342
                     /gene="eutL"
                     /locus_tag="RN951_000891"
     CDS             12683..13342
                     /gene="eutL"
                     /locus_tag="RN951_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HDX2525939.1"
                     /translation="MPALDLIRPSVTAMRVIASVNAEFARELKLPPHIRSLGLISADS
                     DDVTYIAADEATKQAMVEVVYGRSLYAGAAHGPSPTAGEVLIMLGGPNPAEVRAGLDA
                     MVAHIENGAAFQWANDAENTAFLAHVVSRTGSYLSSTAGITLGDPMAYLVAPPLEATY
                     GIDAALKSADVQLVTYVPPPSETNYSAAFLTGSQAACKAACNAFTDAVLEIARNPIQR
                     A"
     gene            13355..13855
                     /gene="eutK"
                     /locus_tag="RN951_000892"
     CDS             13355..13855
                     /gene="eutK"
                     /locus_tag="RN951_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416933.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutK"
                     /protein_id="HDX2525940.1"
                     /translation="MINALGLLEVDGMVAAIDAADAMLKAANVRLLSHEVLDPGRLTL
                     VVEGDLAACRAALDAGCAAAMRTGRVISRKEIGRPDDDTQWLVTGFNRQPKQPVREPD
                     APVIVAESADELLALLTSVRQGMTAGEVAAHFGWPLEKARNALEQLFSAGTLRKRSSR
                     YRLKPH"
     gene            13901..14953
                     /gene="eutR"
                     /locus_tag="RN951_000893"
     CDS             13901..14953
                     /gene="eutR"
                     /locus_tag="RN951_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator EutR"
                     /protein_id="HDX2525941.1"
                     /translation="MKKTRTANLHHLYHEPLPENLKLTPKVEVDNVHQRQTTDVYEHA
                     LTITAWQQIYDQLHPGKFHGEFTEILLDDIQVFREYTGLALRQSCLVWPNSFWFGIPA
                     TRGEQGFIGSQCLGSAEIATRPGGTEFELSTPDDYTILGVVLSEDVITRQANFLHNPD
                     RVLHMLRSQSALEVKEQHKAALWGFVQQALATFCENPENLHQPAVRKVLGDNLLMAMG
                     AMLEDAQPMVTAESISHQSYRRLLSRAREYVLENMSEPVTVLDLCNQLHVSRRTLQNA
                     FHAILGIGPNAWLKRIRLNAVRRELISPWSQSTTVKDAAMQWGFWHLGQFATDYQQLF
                     AEKPSLTLHQRMREWG"
     gene            complement(14959..15858)
                     /gene="hemF"
                     /locus_tag="RN951_000894"
     CDS             complement(14959..15858)
                     /gene="hemF"
                     /locus_tag="RN951_000894"
                     /EC_number="1.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-dependent coproporphyrinogen oxidase"
                     /protein_id="HDX2525942.1"
                     /translation="MKPDAHQVKQFLLNLQDTICQQLTAVDGAEFVEDSWQREAGGGG
                     RSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYV
                     PTSHANVRFFIAEKPGAEPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCLPFGEDVY
                     PRYKKWCDDYFYLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGKGYTDAYLPIVE
                     RRKAMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEY
                     DYQPKDGSPEAALSEFIKVRDWV"
     gene            complement(15862..16731)
                     /gene="amiA"
                     /locus_tag="RN951_000895"
     CDS             complement(15862..16731)
                     /gene="amiA"
                     /locus_tag="RN951_000895"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiA"
                     /protein_id="HDX2525943.1"
                     /translation="MSTFKPLKTLTSRRQVLKAGLAALTLSGMSQAIAKDEPLKTSNG
                     HSKPKAKKSGGKRVVVLDPGHGGIDTGAIGRNGSKEKHVVLAIAKNVRSILRNHGIDA
                     RLTRSGDTFIPLYDRVEIAHKHGADLFMSIHADGFTNPKAAGASVFALSNRGASSAMA
                     KYLSERENRADEVAGKKATDKDHLLQQVLFDLVQTDTIKNSLMLGSHILKKIKPVHKL
                     HSRNTEQAAFVVLKSPSVPSVLVETSFITNPEEERLLGTAAFRQKIATAIAEGVISYF
                     HWFDNQKAHSKKR"
     gene            16945..17370
                     /locus_tag="RN951_000896"
     CDS             16945..17370
                     /locus_tag="RN951_000896"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311332.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HDX2525944.1"
                     /translation="MEIRVFRQEDFEEVITLWERCDLLRPWNDPEMDIERKMNHDVSL
                     FLVAEVNGEVVGTVMGGYDGHRGSAYYLGVHPEFRGRGIANALLNRLEKKLIARGCPK
                     IQINVPEDNDMVLGMYERLGYEHADVLSLGKRLIEDEEY"
     gene            17357..17806
                     /locus_tag="RN951_000897"
     CDS             17357..17806
                     /locus_tag="RN951_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311331.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2919 domain-containing protein"
                     /protein_id="HDX2525945.1"
                     /translation="MKSTEFHPVHYDAHGRLRLPLLFWLVLLLQARTWVLFVIAGASR
                     EQGTALLNLFYPDHDNFWLGLIPGIPAVLAFLLSGRRATFPRTWHVLYFLLLLAQVVL
                     LCWQPWLWLNGESVSGIGLALVVADIVALIWLLTNRRLRACFNEVKE"
     gene            17867..18442
                     /locus_tag="RN951_000898"
     CDS             17867..18442
                     /locus_tag="RN951_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpoE-regulated lipoprotein"
                     /protein_id="HDX2525946.1"
                     /translation="MKSLRLMLCAMPLMLTGCSTMSSVNWSAANPWNWFGSSTKVSEQ
                     GVGELTASTPLQEQAIADALDGDYRLRSGMKTANGNVVRFFEVMKGDNVAMVINGDQG
                     TISRIDVLDSDIPADTGVKIGTPFSDLYSKAFGNCQKADGDDNRAVECKAEGSQHISY
                     QFSGEWSGPEGLMPSDDTLKNWKVSKIIWRR"
     gene            18538..19437
                     /gene="yfeX"
                     /locus_tag="RN951_000899"
     CDS             18538..19437
                     /gene="yfeX"
                     /locus_tag="RN951_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311329.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphyrinogen peroxidase"
                     /protein_id="HDX2525947.1"
                     /translation="MSQVQSGILPEHCRAAIWIEANVKGEVDALRAASKTFADKLATF
                     EAKFPDAHLGAVVAFGNNTWRALSGGVGAEELKDFPGYGKGLAPTTQFDVLIHILSLR
                     HDVNFSVAQAAMEAFGDCIEVKEEIHGFRWVEERDLSGFVDGTENPAGEETRREVAVI
                     KDGVDAGGSYVFVQRWEHNLKQLNRMSVHDQEMMIGRTKEANEEIDGDERPETSHLTR
                     VDLKEDGKGLKIVRQSLPYGTASGTHGLYFCAYCARLHNIEQQLLSMFGDTDGKRDAM
                     LRFTKPVTGGYYFAPSLDKLMAL"
     gene            complement(19495..20799)
                     /gene="pbp4b"
                     /locus_tag="RN951_000900"
     CDS             complement(19495..20799)
                     /gene="pbp4b"
                     /locus_tag="RN951_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin binding protein PBP4B"
                     /protein_id="HDX2525948.1"
                     /translation="MKRTMLYLSLLAVSCSVSAAKYPVLTESSPEKAGFNVERLNQMD
                     RWISQQVDAGYPGVNLLIIKDNQIVYRKAWGAAKKYDGSVLMEQPVKATTGTLYDLAS
                     NTKMYATNFALQKLMSEGKLHPDDRIAKYIPGFADSPNDTIKGKNTLRISDLLHHSGG
                     FPADPQYPNKAVAGALYSQDKGQTLEMIKRTPLEYQPGSKHIYSDVDYMLLGFIVESV
                     TGQPLDRYVEESIYRPLGLTHTVFNPLLKGFKPQQIAATELNGNTRDGVIHFPNIRTS
                     TLWGQVHDEKAFYSMGGVSGHAGLFSNTGDIAVLMQTMLNGGGYGDVQLFSAETVKMF
                     TTSSKEDATFGLGWRVNGNATMTPTFGTLASPQTYGHTGWTGTVTVIDPVNHMAIVML
                     SNKPHSPVADPQKNPNMFESGQLPIATYGWVVDQVYAALKQK"
     gene            complement(20804..22228)
                     /gene="murP"
                     /locus_tag="RN951_000901"
     CDS             complement(20804..22228)
                     /gene="murP"
                     /locus_tag="RN951_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylmuramic acid transporter subunit
                     IIBC"
                     /protein_id="HDX2525949.1"
                     /translation="MAKEISSELLNTILTRVGGPGNIASCGNCMTRLRLGVHDSSLVD
                     PNIKTLEGVKGVILTSDQVQVVFGPGKAHRAAKAMSELLGEAPVQDAAEIAAQNKRQL
                     KAKQTSGVQQFLAKFATIFTPLIPGFIAAGLLLGIATLIATVMHVPADAQGTLPDALN
                     FMKVFSKGLFTFLVILVGYNAAQAFGGTGVNGAIIAALFLLGYNPAATTGYYAGFHDF
                     FGLPIDPRGNIIGVLIAAWACARIEGMVRRFMPDDLDMLLTSLITLLITATLAYLIIM
                     PLGGWLFEGMSWLFMHLNSNPLGCAVLAGLFLIAVVFGVHQGFIPVYLALMDSQGFNS
                     LFPILSMAGAGQVGAALALYWRAQPHSALRSQVRGAIIPGLLGVGEPLIYGVTLPRMK
                     PFITACLGGAAGGLFIGLIAWWGLPMGLNSAFGPSGLVALPLMTSAQGILPAMAVYAG
                     GILVAWVCGFIFTTLFGCRNVNLD"
     gene            complement(22232..23128)
                     /gene="murQ"
                     /locus_tag="RN951_000902"
     CDS             complement(22232..23128)
                     /gene="murQ"
                     /locus_tag="RN951_000902"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDX2525950.1"
                     /translation="MQLEKMITEGSNTASAEIDRVSTLEMCRIINDEDKTVPLAVERV
                     LPDIAAAIDVIHAQVSGGGRLIYLGAGTSGRLGILDASECPPTYGVKPGLVVGLIAGG
                     EYAIQHAVEGAEDSREGGVNDLKNINLTAQDVVVGIAASGRTPYVIAGLEYARQLGCR
                     TVGISCNPGSAVSTTAEFAITPIVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGK
                     VFGNLMVDVVATNEKLHVRQVNIVKNATGCNAEQAEAALIACERNCKTAIVMVLKNLD
                     AAEAKKRLDQHGGFIRQVLDKE"
     gene            23292..24149
                     /gene="murR"
                     /locus_tag="RN951_000903"
     CDS             23292..24149
                     /gene="murR"
                     /locus_tag="RN951_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MurR"
                     /protein_id="HDX2525951.1"
                     /translation="MLYLTKISNAGSEFTENEQKIADFLQANVSELQSVSSRQMAKQL
                     GISQSSIVKFAQKLGAQGFTELRMALIGEYSASREKTNATALHLHSSITSDDSLEVIA
                     RKLNREKELALEQTCSLFDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKI
                     GYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSL
                     ADSPLRRLAHFTLDTVSGETEWRSSSMSTRTAQNSVTDLLFVGLVQLNDVESLKMIQR
                     SSELTQRLK"
     gene            24278..25069
                     /gene="ucpA"
                     /locus_tag="RN951_000904"
     CDS             24278..25069
                     /gene="ucpA"
                     /locus_tag="RN951_000904"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416921.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase UcpA"
                     /protein_id="HDX2525952.1"
                     /translation="MGKLTGKTALITGALQGIGEGIARTFARHGANLILLDISPEIEK
                     LADELCGRGHRCTAVVADVRDPASVAAAIKRAKEKEGRIDILVNNAGVCRLGSFLDMS
                     DDDRDFHIDINIKGVWNVTKAVLPEMIARKDGRIVMMSSVTGDMVADPGETAYALTKA
                     AIVGLTKSLAVEYAQSGIRVNAICPGYVRTPMAESIARQSNPEDPESVLTEMAKAIPM
                     RRLADPLEVGELAAFLASDESSYLTGTQNVIDGGSTLPETVSVGI"
     gene            25240..26256
                     /gene="cysP"
                     /locus_tag="RN951_000905"
     CDS             25240..26256
                     /gene="cysP"
                     /locus_tag="RN951_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate/sulfate ABC transporter
                     substrate-binding protein CysP"
                     /protein_id="HDX2525953.1"
                     /translation="MAVNLLKKNSLALVASLLLAGHVQATELLNSSYDVSRELFAALN
                     PPFEQQWAKDNGGDKLTIKQSHAGSSKQALAILQGLKADVVTYNQVTDVQILHDKGKL
                     IPADWQSRLPNNSSPFYSTMGFLVRKGNPKNIHDWNDLVRSDVKLIFPNPKTSGNARY
                     TYLAAWGAADKADGGDKAKTEQFMTQFLKNVEVFDTGGRGATTTFAERGLGDVLISFE
                     SEVNNIRKQYEAQGFEVVIPKTNILAEFPVAWVDKNVQANGTEKAAKAYLNWLYSPQA
                     QTIITDYYYRVNNPEVMDKLKNKFPQTELFRVEDKFGSWPEVMKTHFTSGGELDKLLA
                     AGRN"
     gene            26256..27089
                     /gene="cysT"
                     /locus_tag="RN951_000906"
     CDS             26256..27089
                     /gene="cysT"
                     /locus_tag="RN951_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysT"
                     /protein_id="HDX2525954.1"
                     /translation="MFAVSSRRVLPGFTLSLGTSLLFVCLILLLPLSALVMQLAQMSW
                     AQYWEVITNPQVVAAYKVTLLSAFVASIFNGVFGLLMAWILTRYRFPGRTLLDALMDL
                     PFALPTAVAGLTLASLFSVNGFYGEWLAKFDIKVTYTWLGIAVAMAFTSIPFVVRTVQ
                     PVLEELGPEYEEAAETLGATRWQSFCKVVLPELSPALVAGVALSFTRSLGEFGAVIFI
                     AGNIAWKTEVTSLMIFVRLQEFDYPAASAIASVILAASLLLLFSINTLQSRFGRRVVG
                     H"
     gene            27089..27964
                     /gene="cysW"
                     /locus_tag="RN951_000907"
     CDS             27089..27964
                     /gene="cysW"
                     /locus_tag="RN951_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysW"
                     /protein_id="HDX2525955.1"
                     /translation="MAEVTQLKRYDARPINWGKWFLIGIGMLVSAFILLVPMIYIFVQ
                     AFSKGLMPVLQNLADPDMLHAIWLTVMIALIAVPVNLVFGILLAWLVTRFNFPGRQLL
                     LTLLDIPFAVSPVVAGLVYLLFYGSNGPLGGWLDEHNLQIMFSWPGMVLVTIFVTCPF
                     VVRELVPVMLSQGSQEDEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEF
                     GAVSVVSGSIRGETLSLPLQIELLEQDYNTVGSFTAAALLTLMAIITLFLKSMLQWRL
                     ENQEKRAQQEEHHEH"
     gene            27954..29051
                     /gene="cysA"
                     /locus_tag="RN951_000908"
     CDS             27954..29051
                     /gene="cysA"
                     /locus_tag="RN951_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter ATP-binding
                     protein CysA"
                     /protein_id="HDX2525956.1"
                     /translation="MSIEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTL
                     LRIIAGLEHQTSGHIRFHGTDVSRLHARDRKVGFVFQHYALFRHMTVFDNIAFGLTVL
                     PRRERPNAAAIKAKVTKLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLL
                     DEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEATEVADRVVVMSQGNIEQA
                     DAPNQVWREPATRFVLEFMGEVNRLQGTIRGGQFHVGAHRWPLGYTPAYQGPVDLFLR
                     PWEVDISRRTSLDSPLPVQVLEASPKGHYTQLVVQPLGWYNEPLTVVMHGDDAPQRGE
                     RLFVGLQHARLYNGDERIETRDEELALAQSA"
     gene            29185..30096
                     /gene="cysM"
                     /locus_tag="RN951_000909"
     CDS             29185..30096
                     /gene="cysM"
                     /locus_tag="RN951_000909"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase B"
                     /protein_id="HDX2525957.1"
                     /translation="MSTLEQTIGNTPLVKLQRMGPDNGSEVWLKLEGNNPAGSVKDRA
                     ALSMIVEAEKRGEIKPGDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAA
                     MRAYGAELILVTKEQGMEGARDLALEMANRGEGKLLDQFNNPDNPYAHYTTTGPEIWQ
                     QTGGRITHFVSSMGTTGTITGVSRFMREQSKPVTIVGLQPEEGSSIPGIRRWPAEYLP
                     GIFNASLVDEVLDIHQRDAENTMRELAVREGIFCGVSSGGAVAGALRVAKANPGAVVV
                     AIICDRGDRYLSTGVFGEEHFSQGAGI"
     gene            complement(30099..30467)
                     /locus_tag="RN951_000910"
     CDS             complement(30099..30467)
                     /locus_tag="RN951_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfeK family protein"
                     /protein_id="HDX2525958.1"
                     /translation="MKKIICLVITLLMTLPAYAKLTAHEEARINAMLEGLAQKKDLIF
                     VRNGDEHTCDEAVSHLRLKLGNTRNRIDTAEQFIDKVASSSSITGKPYIVKIPGKSDE
                     NAQPFLHALIAQTDKTVPAQ"
     gene            30572..31423
                     /gene="pdxK"
                     /locus_tag="RN951_000911"
                     /gene_synonym="thiJ"
     CDS             30572..31423
                     /gene="pdxK"
                     /locus_tag="RN951_000911"
                     /gene_synonym="thiJ"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine/pyridoxal/pyridoxamine kinase"
                     /protein_id="HDX2525959.1"
                     /translation="MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGL
                     NVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYLRALQERDALRQLRAVTTGYMGTASQ
                     IKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNI
                     FELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVITSASGNEENQEMQVVVVSADSVNV
                     ISHSRVKTDLKGTGDLFCAQLISGLLKGKALNDAVHRAGLRVLEVMRYTQQHESDELI
                     LPPLAEA"
     gene            complement(31465..31974)
                     /gene="crr"
                     /locus_tag="RN951_000912"
     CDS             complement(31465..31974)
                     /gene="crr"
                     /locus_tag="RN951_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015833547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDX2525960.1"
                     /translation="MGLFDKLKSLVSDDKKDTGTIEIIAPLSGEIVNIEDVPDVVFAE
                     KIVGDGIAIKPTGNKMVAPVDGTIGKIFETNHAFSIESDSGVELFVHFGIDTVELKGE
                     GFKRIAEEGQRVKVGDTVIEFDLPLLEEKAKSTLTPVVISNMDEIKELIKLSGSVTVG
                     ETPVIRIKK"
     gene            complement(32015..33742)
                     /gene="ptsI"
                     /locus_tag="RN951_000913"
     CDS             complement(32015..33742)
                     /gene="ptsI"
                     /locus_tag="RN951_000913"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate-protein phosphotransferase
                     PtsI"
                     /protein_id="HDX2525961.1"
                     /translation="MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFL
                     SGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADA
                     AAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVA
                     ADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYL
                     ILDAVNNQVYVNPTNEVIDKMRAVQEQVASEKAELAKLKDLPAITLDGHQVEVCANIG
                     TVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFAAYKAVAEACGSQAVIVRTM
                     DIGGDKELPYMNFPKEENPFLGWRAIRIAMDRKEILRDQLRAILRASAFGKLRIMFPM
                     IISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGVMVETPAAATIARHLAKEVDFFS
                     IGTNDLTQYTLAVDRGNDMISHLYQPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGD
                     ERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELMTLVN
                     KFIEEKTIC"
     gene            complement(33787..34044)
                     /gene="ptsH"
                     /locus_tag="RN951_000914"
     CDS             complement(33787..34044)
                     /gene="ptsH"
                     /locus_tag="RN951_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein Hpr"
                     /protein_id="HDX2525962.1"
                     /translation="MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASA
                     KSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKLMAELE"
     gene            complement(34428..35399)
                     /gene="cysK"
                     /locus_tag="RN951_000915"
     CDS             complement(34428..35399)
                     /gene="cysK"
                     /locus_tag="RN951_000915"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HDX2525963.1"
                     /translation="MSKIFEDNSLTIGHTPLVRLNRIGNGRILAKVESRNPSFSVKCR
                     IGANMIWDAEKRGVLKPGVELVEPTSGNTGIALAYVAAARGYKLTLTMPETMSIERRK
                     LLKALGANLVLTEGAKGMKGAIQKAEEIVASNPEKYLLLQQFSNPANPEIHEKTTGPE
                     IWEDTDGQVDVFIAGVGTGGTLTGVSRYIKGTKGKTDLISVAVEPTDSPVIAQALAGE
                     EIKPGPHKIQGIGAGFIPANLDLKLVDKVIGITNEEAISTARRLMEEEGILAGISSGA
                     AVAAALKLQEDESFTNKNIVVILPSSGERYLSTALFADLFTEKELQQ"
     gene            complement(35584..36345)
                     /gene="cysZ"
                     /locus_tag="RN951_000916"
     CDS             complement(35584..36345)
                     /gene="cysZ"
                     /locus_tag="RN951_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate transporter CysZ"
                     /protein_id="HDX2525964.1"
                     /translation="MVSSFTSAPRSGFYYFAQGWKLVSQPGIRRFVILPLLVNILLMG
                     GAFWWLFTQLDVWIPTLMSYVPDWLQWLSYLLWPLAVISVLLVFGYFFSTIANWIAAP
                     FNGLLAEQLEARLTGATPPDTGIFGIMKDVPRIMKREWQKFAWYLPRAIVLLILYLIP
                     GIGQTVAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKEMRTALRTRKITNMQFGALTSL
                     FTMIPLLNLFIMPVAVCGATAMWVDCYRDKHAMWR"
     gene            36575..37561
                     /gene="zipA"
                     /locus_tag="RN951_000917"
     CDS             36575..37561
                     /gene="zipA"
                     /locus_tag="RN951_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZipA"
                     /protein_id="HDX2525965.1"
                     /translation="MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRM
                     KSKRDDDSYDEDVEDDEGVGEVRVHRVNHAPANAQEHEAARPSPQHQYQPPYASAQPR
                     QPVQQPPEAQVPPQHAPRPAQPVQQPAYQPQPEQPLQQPVSPQVAPAPQPVHSAPQPA
                     QQAFQPAEPVAAPQPEPVAEPAPVMDKPKRKEAVIIMNVAAHHGSELNGELLLNSIQQ
                     AGFIFGDMNIYHRHLSPDGSGPALFSLANMVKPGTFDPEMKDFTTPGVTIFMQVPSYG
                     DELQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDIIREVKDANA"
     gene            37632..39647
                     /gene="ligA"
                     /locus_tag="RN951_000918"
     CDS             37632..39647
                     /gene="ligA"
                     /locus_tag="RN951_000918"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HDX2525966.1"
                     /translation="MESIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRE
                     LETKHPELITPDSPTQRVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRL
                     KNNEKVTWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLH
                     GENIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKR
                     PLTFFCYGVGVLEGGELPDTHLGRLLQFKKWGLPVSDRVTLCESAEEVLAFYHKVEED
                     RPTLGFDIDGVVIKVNSLEQQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRT
                     GAITPVARLEPVHVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVL
                     SERPEDTREVVFPTHCPVCGSDVERVEGEAVARCTGGLICGAQRKESLKHFVSRRAMD
                     VDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMGPKSAQNVVNALEKAKETTF
                     ARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKVPDVGIVVASHVHNFFAE
                     ESNRNVISELLAEGVHWPAPIVINAEEIDSPFAGKTVVLTGSLSQMSRDDAKARLVEL
                     GAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDEAEMLRLLGS"
     gene            39649..39867
                     /locus_tag="RN951_000919"
     CDS             39649..39867
                     /locus_tag="RN951_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3820 family protein"
                     /protein_id="HDX2525967.1"
                     /translation="MEKEQLIEIANTIMPFGKYKGRRLIDLPEEYLLWFARKDEFPAG
                     KLGELMQITLLIKTEGLTQLVQPLKRPL"
     gene            complement(39864..40862)
                     /locus_tag="RN951_000920"
     CDS             complement(39864..40862)
                     /locus_tag="RN951_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid:sodium symporter"
                     /protein_id="HDX2525968.1"
                     /translation="MKLFRILDPFTLTLITVVLLASFFPARGDFVPFFENLTTAAIAL
                     LFFMHGAKLSREAIIAGGGHWRLHLWVMCSTFVLFPILGVLFAWWKPVNVDPMLYSGF
                     LYLCILPATVQSAIAFTSMAGGNVAAAVCSASASSLLGIFLSPLLVGLVMNVHGAGGS
                     LEQVGKIMLQLLLPFVLGHLSRPWIGDWVSRNKKWIAKTDQTSILLVVYTAFSEAVVN
                     GIWHKVGWGSLLFIVVVSCVLLAIVIVVNVFMARRLGFNKADEITIVFCGSKKSLANG
                     IPMANILFPTSVIGMMVLPLMIFHQIQLMVCAVLARRYKRQTEQLQAQQESSADKA"
     gene            40952..41878
                     /locus_tag="RN951_000921"
     CDS             40952..41878
                     /locus_tag="RN951_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX2525969.1"
                     /translation="MNYSLKQLKVFVTVAQEKSFSRAGERIGLSQSAVSHSVKELENH
                     TGVRLLDRTTREVVLTDAGQQLALRLERLLDELNSTLRDTGRMGQQLSGKVRVAASQT
                     ISAHLIPQCIAESHRRYPDIQFVLHDRPQQWVMESIRQGDVDFGIVIDPGPVGDLQCE
                     AILSEPFFLLCHRDSALAVEDYVPWQALQEAKLVLQDYASGSRPLIDAALARNGIQAN
                     IVQEIGHPATLFPMVAAGIGISILPALALPLPEGSPLVVKRITPVVERQLMLVRRKNR
                     SLSTAAEALWDVVRDQGNALMAGREGDPLYQI"
     gene            complement(41869..42210)
                     /locus_tag="RN951_000922"
     CDS             complement(41869..42210)
                     /locus_tag="RN951_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FlxA-like family protein"
                     /protein_id="HDX2525970.1"
                     /translation="MATISSTSIPSIQTQSSNRASQGSDVASQIARISQQIIKLTQQI
                     KEIVDTSGSAEDKQKQAELIQQQITLLETQLAQLQKQQAEKAQEKEQCLSLNVSLLNP
                     VEKTTHIDIYI"
     gene            complement(42330..42405)
                     /locus_tag="RN951_000923"
     tRNA            complement(42330..42405)
                     /locus_tag="RN951_000923"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(42370..42372),aa:Lys,seq:ttt)
     gene            complement(42410..42485)
                     /locus_tag="RN951_000924"
     tRNA            complement(42410..42485)
                     /locus_tag="RN951_000924"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(42450..42452),aa:Val,seq:tac)
     gene            complement(42532..42607)
                     /locus_tag="RN951_000925"
     tRNA            complement(42532..42607)
                     /locus_tag="RN951_000925"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(42572..42574),aa:Val,seq:tac)
     gene            complement(42652..42727)
                     /locus_tag="RN951_000926"
     tRNA            complement(42652..42727)
                     /locus_tag="RN951_000926"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(42692..42694),aa:Val,seq:tac)
     gene            42986..44401
                     /gene="gltX"
                     /locus_tag="RN951_000927"
     CDS             42986..44401
                     /gene="gltX"
                     /locus_tag="RN951_000927"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HDX2525971.1"
                     /translation="MKIKTRFAPSPTGYLHVGGARTALYSWLFARNHGGEFVLRIEDT
                     DLERSTPEAIEAIMDGMNWLSLEWDEGPYYQTKRFDRYNAVIDQMLEEGTAYKCYCSK
                     ERLEALREEQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQEGSVVFDDQIRGPI
                     EFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALK
                     APVPVYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEI
                     FTREEMIKYFTLNAVSKSASAFNTDKLLWLNHHYINALPPEYVATHLQWHIEQENIDT
                     RNGPQLADLVKLLGERCKTLKEMAQSCRYFYEDFAEFDADAAKKHLRPVARQPLEVVR
                     DKLAAITDWTAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGK
                     TRSIERINKALDFIAERENQQ"
     gene            complement(44453..44845)
                     /locus_tag="RN951_000928"
     CDS             complement(44453..44845)
                     /locus_tag="RN951_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416898.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="HDX2525972.1"
                     /translation="MKRLRNKMTTEELAECLGVAKQTVNRWIREKGWKTEKFPGVKGG
                     RARLILVDTQVCEFIQNTPAFHNTPMLMEAEERIAEYAPGARAPAYRQIINAIDNMTD
                     IEQEKVAQFLSREGIRNFLARLDIDESA"
     gene            complement(44847..45206)
                     /locus_tag="RN951_000929"
     CDS             complement(44847..45206)
                     /locus_tag="RN951_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311301.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="HDX2525973.1"
                     /translation="MFKERMTPDELARLTGYSRQTINKWVRKEGWTTSPKPGVQGGKA
                     RLVHVNEQVREYIRNAERPEGQGEAPALSGDAPLEVLLVTLAKEMTPVEQKQFTSLLL
                     REGIIGLLQRLGIRDSK"
     gene            45427..45502
                     /locus_tag="RN951_000930"
     tRNA            45427..45502
                     /locus_tag="RN951_000930"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45460..45462,aa:Ala,seq:ggc)
     gene            45542..45617
                     /locus_tag="RN951_000931"
     tRNA            45542..45617
                     /locus_tag="RN951_000931"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45575..45577,aa:Ala,seq:ggc)
     gene            45826..48015
                     /locus_tag="RN951_000932"
     CDS             45826..48015
                     /locus_tag="RN951_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416896.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor domain-containing phosphodiesterase"
                     /protein_id="HDX2525974.1"
                     /translation="MFVEHNLIKNIKIFTLAFTLTVVLIQLSRFISPLAIIHSSYIFL
                     AWMPLCVMLSILFIFGWRGVVPVLCGMFCTNLWNFHLSFLQTAVMLGSQTFVVLCACA
                     ILRWQLGTRWRYGLTSRYVWQRLFWLGLVTPIGIKCSMYLVGSFFDFPLKISTFFGDA
                     DAIFTVVDLLSLFTAVLIYNMLFYYLTRMIVSPHFAQILWRRDIAPSLGKEKRAFTLS
                     WLAALSVLLLLLCTPYENDFIAGYLVPVFFIIFTLGVGKLRYPFLNLTWAVSTLCLLN
                     YNQNFLQGVETEYSLAFILAVLISFSVCLLYMVRIYHRSEWLNRRWHLQALTDPLTLL
                     PNFRALEQAPEQEAGKSFCCLRIDNLEFMSRHYGLMMRVHCIRSICRTLLPLMQENEK
                     LYQLPGSELLLVLSGPETEGRLQHMVNILNSRQIHWNNTGLDMGYGAAWGRFDGNQET
                     LQPLLGQLSWLAEQSCAHHHVLALDSREEMVSGQTTKQVLLLNTIRTALDQGDLLLYA
                     QPIRNKEGEGYDEILARLKYDGGIMTPDKFLPLIAQFNLSARFDLQVLESLLKWLATH
                     PCDKKGPRFSVNLMPLTLLQKNIAGRIIRLFKRYHISPQAVILEITEEQAFSNAESSM
                     YNIEQLHKFGFRIAIDDFGTGYANYERLKRLQADIIKIDGVFVKDIVTNTLDAMIVRS
                     ITDLAKAKSLSVVAEFVETQQQQALLHKLGVQYLQGYLIGRPQPLAD"
     gene            complement(48065..49267)
                     /gene="nupC"
                     /locus_tag="RN951_000933"
     CDS             complement(48065..49267)
                     /gene="nupC"
                     /locus_tag="RN951_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease NupC"
                     /protein_id="HDX2525975.1"
                     /translation="MDRVLHFVLALAVVAILALLVSSDRKKIRIRYVIQLLVIEVLLA
                     WFFLNSDVGLGFVKGFSEMFEKLLGFANEGTNFVFGSMNDQGLAFFFLKVLCPIVFIS
                     ALIGILQHIRVLPVIIRAIGFLLSKVNGMGKLESFNAVSSLILGQSENFIAYKDILGK
                     ISRNRMYTMAATAMSTVSMSIVGAYMTMLEPKYVVAALVLNMFSTFIVLSLINPYRVD
                     ASEENIQMSNLHEGQSFFEMLGEYILAGFKVAIIVAAMLIGFIALIAALNALFATVTG
                     WFGYSISFQGILGYIFYPIAWVMGVPSSEALQVGSIMATKLVSNEFVAMMDLQKIAST
                     LSPRAEGIISVFLVSFANFSSIGIIAGAVKGLNEEQGNVVSRFGLKLVYGSTLVSVLS
                     ASIAALVL"
     gene            49603..50841
                     /locus_tag="RN951_000934"
     CDS             49603..50841
                     /locus_tag="RN951_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HDX2525976.1"
                     /translation="MTNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQA
                     GASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAE
                     IIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGL
                     LLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSS
                     LTQHLHGGSRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAY
                     LTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRFHIPLWVRRTVTMLP
                     SFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWV
                     IVVLVVALNIWLLVGTALGL"
     gene            complement(50982..51308)
                     /locus_tag="RN951_000935"
     CDS             complement(50982..51308)
                     /locus_tag="RN951_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2502 domain-containing protein"
                     /protein_id="HDX2525977.1"
                     /translation="MFRSLFLAAALMAFTPLAANAGEITLLPSIKLQIGDRDHYGNYW
                     DGGHWRDRDYWHRNYEWRKNRWWRHDNGYHRGWDKRKAYERGYREGWRDRDDHRGKGR
                     GHGHRH"
     gene            complement(51423..52679)
                     /locus_tag="RN951_000936"
     CDS             complement(51423..52679)
                     /locus_tag="RN951_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion channel protein"
                     /protein_id="HDX2525978.1"
                     /translation="MLHPRARTMLLLSLPAVAIGIASSLILIVVMKIASVLQNLLWQR
                     LPGTLGIAQDSPLWIIGVLTLTGIAVGLVIRFSQGHAGPDPACEPLIGAPVPPSALPG
                     LIVALILGLAGGVSLGPEHPIMTVNIALAVAIGARLLPRVNRMEWTILASAGTIGALF
                     GTPVAAALIFSQTLNGSSEVPLWDRLFAPLMAAAAGALTTGLFFHPHFSLPIAHYGQM
                     EMTDILSGAIVAAIAIAAGMVAVWCLPRLHAMMHQMKNPVLVLGIGGFILGILGVIGG
                     PVSLFKGLDEMQQMVANQAFSTSDYFLLAVIKLAALVVAAASGFRGGRIFPAVFVGVA
                     LGLMLHEHVPAVPAAITVSCAILGIVLVVTRDGWLSLFMAAVVVPNTTLLPLLCIVML
                     PAWLLLAGKPMMMVNRPKQQPPHDNV"
     gene            52883..53848
                     /gene="glk"
                     /locus_tag="RN951_000937"
     CDS             52883..53848
                     /gene="glk"
                     /locus_tag="RN951_000937"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucokinase"
                     /protein_id="HDX2525979.1"
                     /translation="MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAV
                     IRVYLEEHKVEVKDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFT
                     AVSMAIPMLKKEHLIQFGGAEPVEGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGH
                     VDFAPNSEEEAIILEILRAEIGHVSAERVLSGPGLVNLYRAIVKADNRLPENLKPKDI
                     TERALADSCTDCRRALSLFCVIMGRFGGNLALNLGTFGGVFIAGGIVPRFLEFFKASG
                     FRAAFEDKGRFKEYVHDIPVYLIVHDNPGLLGSGAHLRQTLGHIL"
     gene            54067..54393
                     /locus_tag="RN951_000938"
     CDS             54067..54393
                     /locus_tag="RN951_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-like phosphotransferase enzyme IIB
                     component 1"
                     /protein_id="HDX2525980.1"
                     /translation="MSKKLIALCACPMGLAHTFMAAQALEEAAVEAGYEVKIETQGAD
                     GIQNRLTAQDIAEATIIIHSVAVTPEDNERFESRDVYEITLQDAIKNAAGIIKEIEEM
                     IASEQQ"
     gene            54415..55662
                     /locus_tag="RN951_000939"
     CDS             54415..55662
                     /locus_tag="RN951_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDX2525981.1"
                     /translation="MAIKKRSATVVPGASGAAAAVKNPQASKTSFWGELPQHVMSGIS
                     RMVPTLIMGGVILAFSQLIAYSWLKIPAEIGIMDALNSGKFSGFDLSLLKFAWLSQSF
                     GGVLFGFAIPMFAAFVANSIGGKLAFPAGFIGGLMSTQPTQLLNFDPSTMQWATSSPV
                     PSTFIGALIISIVAGYLVKWMNQKIQLPDFLLAFKTTFLLPILSAIFVMLAMYYVITP
                     FGGWINGGIRTVLTAAGEKGALMYAMGIAAATAIDLGGPINKAAGFVAFSFTTDHVLP
                     VTARSIAIVIPPIGLGLATIIDRRLTGKRLFNAQLYPQGKTAMFLAFMGISEGAIPFA
                     LESPITAIPSYMVGAIVGSTAAVWLGAVQWFPESAIWAWPLVTNLGVYMAGIALGAVI
                     TALMVVFLRLMMFRKGKLLIDSL"
     gene            55677..56762
                     /gene="ypdF"
                     /locus_tag="RN951_000940"
     CDS             55677..56762
                     /gene="ypdF"
                     /locus_tag="RN951_000940"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDX2525982.1"
                     /translation="MTLLASLRDWLKAQQLDAVLLSSRQNKQPHLGISTGSGYVVISR
                     ESAHILVDSRYYVEVEARAQGYQLHLLDATNTLTTIVNQIIADEQLQTLGFEGQQVSW
                     ETAHRWQSELNAKLVSATPDVLRQIKTPEEVEKIRLACGIADRGAEHIRRFIQAGMSE
                     REIAAELEWFMRQQGAEKASFDTIVASGWRGALPHGKASDKIVAAGEFVTLDFGALYQ
                     GYCSDMTRTLLVNGEGVSAESHPLFNVYQIVLQAQLAAISAIRPGVRCQQVDDAARRV
                     ITEAGYGDYFGHNTGHAIGIEVHEDPRFSPRDTTTLQPGMLLTVEPGIYLPGQGGVRI
                     EDVVLVTPQGAEVLYAMPKTVLLTGEA"
     gene            56762..57799
                     /gene="ypdE"
                     /locus_tag="RN951_000941"
     CDS             56762..57799
                     /gene="ypdE"
                     /locus_tag="RN951_000941"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDX2525983.1"
                     /translation="MDLSLLKALSEADAIASSEQEVRQILLEEADRLQKEVRFDGLGS
                     VLIRLNESTGPKVMICAHMDEVGFMVRSISREGAIDVLPVGNVRMAARQLQPVRITTR
                     EECKIPGLLDGDRQGNDVSAMRVDIGARSYDEVMQAGIRPGDRVTFDTTFQVLPHQRV
                     MGKAFDDRLGCYLLVTLLRELHDAELPAEVWLVASSSEEVGLRGGQTATRAVSPDVAI
                     VLDTACWAKNFDYGAANHRQIGNGPMLVLSDKSLIAPPKLTAWVETVAAEIGVPLQAD
                     MFSNGGTDGGAVHLTGTGVPTVVMGPATRHGHCAASIADCRDILQMQQLLSALIQRLT
                     RETVVQLTDFR"
     gene            57824..60319
                     /gene="ptsP"
                     /locus_tag="RN951_000942"
     CDS             57824..60319
                     /gene="ptsP"
                     /locus_tag="RN951_000942"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDX2525984.1"
                     /translation="MLTIQFLCPLPNGLHARPAWELKEQCSQWQSEITFINHRQNAKA
                     DAKSSLALIGTGTLFNDSCSLNISGSDEEQARRVLEEYIQVRFIDSDSVQPTQAELTA
                     HPLPRSLSRLNPDLLYGNVLASGVGVGTLTLLQSDSLDSYRAIPASAQDSTRLEHSLA
                     TLAEQLNQQLRERDGESKTILSAHLSLIQDDEFAGNIRRLMTEQHQGLGAAIISNMEQ
                     VCAKLSASASDYLRERVSDIRDISEQLLHITWPELKPRNKLVLEKPTILVAEDLTPSQ
                     FLSLDLKNLAGMILEKTGRTSHTLILARASAIPVLSGLPLDAIARYAGQPAVLDAQCG
                     VLAINPNDAVSGYYQVAQTLADKRQKQQAQAAAQLAYSRDNKRIDIAANIGTALEAPG
                     AFANGAEGVGLFRTEMLYMDRDSAPDEQEQFEAYQQVLLAAGDKPIIFRTMDIGGDKS
                     IPYLNIPQEENPFLGYRAVRIYPEFAGLFRTQLRAILRAASFGNAQLMIPMVHSLDQI
                     LWVKGEIQKAIVELKRDGLRHAETITLGIMVEVPSVCYIIDHFCDEVDFFSIGSNDMT
                     QYLYAVDRNNPRVSPLYNPITPSFLRMLQQIVTTAHQRGKWVGICGELGGESRYLPLL
                     LGLGLDELSMSSPRIPAVKSQLRQLDSEACRELARQACECRSAQEIEALLTAFTPEED
                     VRPLLALENIFVDQDFSNKEQAIQFLCGNLGVNGRTEHPFELEEDVWQREEIVTTGVG
                     FGVAIPHTKSQWIRHSSISIARLAKPIDWQSEMGEVELVIMLTLGANEGMNHVKVFSQ
                     LARKLVNKNFRQSLFAAQDAQSILTLLETELTF"
     gene            complement(60322..61179)
                     /locus_tag="RN951_000943"
     CDS             complement(60322..61179)
                     /locus_tag="RN951_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX2525985.1"
                     /translation="MKAPGLPADQQFFADLFSGLVLNPQLLGRVWFASQPASLPVGSL
                     CIDFPRLDIVLRGEYGNLLEAKQQRMVEGEMLFIPARAANLPINNKPVMLLSLVFAPT
                     WLGLSFYDSRTTSLLHPARQIQLPSLQRGEGEAMLTALTHLSRSPLEQNIIQPLVLSL
                     LHLCRNVVNMPPGNSQPRGDFLYHSICNWVQDNYAQPLTRESVAQFFNITPNHLSKLF
                     AQHGTMRFIEYVRWVRMAKARMILQKYHLSIHEVAQRCGFPDSDYFCRVFRRQFGLTP
                     GEYSARFQG"
     gene            complement(61192..61926)
                     /gene="ypdB"
                     /locus_tag="RN951_000944"
     CDS             complement(61192..61926)
                     /gene="ypdB"
                     /locus_tag="RN951_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator YpdB"
                     /protein_id="HDX2525986.1"
                     /translation="MKVIIVEDEFLAQQELSWLIKEHSQMEIVGTFDDGLDVLKFLQH
                     NRVDAIFLDINIPSLDGVLLAQNISQFAHKPFIVFITAWKEHAVEAFELEAFDYILKP
                     YQESRITGMLQKLEAAWQQQQTSSTPAATVTRENDTINLVKDERIIVTPINDIYYAEA
                     HEKMTFVYTRRESYVMPMNITEFCSKLPPSHFFRCHRSFCVNLNKIREIEPWFNNTYI
                     LRLKDLDFEVPVSRSKVKEFRQLMHL"
     gene            complement(61941..63638)
                     /gene="ypdA"
                     /locus_tag="RN951_000945"
     CDS             complement(61941..63638)
                     /gene="ypdA"
                     /locus_tag="RN951_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     YpdA"
                     /protein_id="HDX2525987.1"
                     /translation="MHEIFNMLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKE
                     LLAVTAIFSLFALFSTWSGVPVEGSLVNVRIIAVMSGGILFGPWVGIITGVIAGIHRY
                     LIDIGGVTAIPCFITSILAGCISGWINLKIPKAQRWRVGILGGMLCETLTMILVIVWA
                     PTTALGIDIVSKIGIPMILGSVCIGFIVLLVQSVEGEKEASAARQAKLALDIANKTLP
                     LFRHVNSESLRKVCEIIRDDIHADAVAITNTDHVLAYVGVGEHNYQNGDDFISPTTRQ
                     AMNYGKIIIKNNDEAHRTPEIHSMLVIPLWEKGVVTGTLKIYYCHAHQITSSLQEMAV
                     GLSQIISTQLEVSRAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTAR
                     QLIFNLSRYLRYNIELKDDEQIDIKKELYQIKDYIAIEQARFGDKLTVIYDIDEEVNC
                     CIPSLLIQPLVENAIVHGIQPCKGKGVVTISVAECGNRVRIAVRDTGHGIDPKVIERV
                     EANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEIAFYIPNQRTPVASQATLLL"
     gene            64015..65253
                     /gene="alaC"
                     /locus_tag="RN951_000946"
     CDS             64015..65253
                     /gene="alaC"
                     /locus_tag="RN951_000946"
                     /EC_number="2.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase"
                     /protein_id="HDX2525988.1"
                     /translation="MADTRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMG
                     NPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLRRAISHWYQDRYDVEIDPESEAI
                     VTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNE
                     LERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVY
                     DGWKAPSIMQVPGARDVAVEFFTLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYG
                     TFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWMVEMPKASMYVWAKI
                     PEPYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAIRGIKA
                     MFRADGLLPASSKHIHENAE"
     gene            complement(65318..65389)
                     /gene="ypdK"
                     /locus_tag="RN951_000947"
     CDS             complement(65318..65389)
                     /gene="ypdK"
                     /locus_tag="RN951_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_077777854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YpdK"
                     /protein_id="HDX2525989.1"
                     /translation="MKYFFMGISFMVIVWASTFALMI"
     gene            complement(65745..66665)
                     /gene="lpxP"
                     /locus_tag="RN951_000948"
     CDS             complement(65745..66665)
                     /gene="lpxP"
                     /locus_tag="RN951_000948"
                     /EC_number="2.3.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311285.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid IV(A) palmitoleoyltransferase"
                     /protein_id="HDX2525990.1"
                     /translation="MFPQCKFSREFLHPRYWLTWFGLGVLWLWVQLPYPVLCFLGTRI
                     GAMARPFLKRRESIARKNLELCFPQHSAEEREKMIAENFRSLGMALVETGMAWFWPDS
                     RVRKWFDVEGLDNLKRAQMQNRGVMVVGVHFMSLELGGRVMGLCQPMMATYRPHNNQL
                     MEWVQTRGRMRSNKAMIGRNNLRGIVGALKKGEAVWFAPDQDYGRKGSSFAPFFAVEN
                     VATTNGTYVLSRLSGAAMLTVTMVRKADYSGYRLFITPEMEGYPTDENQAAAYMNKII
                     EKEIMRAPEQYLWIHRRFKTRPVGESSLYI"
     gene            67018..67260
                     /locus_tag="RN951_000949"
     CDS             67018..67260
                     /locus_tag="RN951_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdY family protein"
                     /protein_id="HDX2525991.1"
                     /translation="MIYLWMFLALCIVCVSGYIGQVLNVVSAVSSFFGMVILAALIYY
                     FTMWLTGGNELVTGIFMFLAPACGLMIRFMVGYGRR"
     gene            complement(67337..>67573)
                     /locus_tag="RN951_000950"
     CDS             complement(67337..>67573)
                     /locus_tag="RN951_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2525992.1"
                     /translation="VSIMACNVFAFSISGGVSERSYKETEKTSAMTTTHSTKLQPSQA
                     ILFKMREDAPPLNLTEEITPTYPTKANYLIHPVR"
BASE COUNT        15894 a        17083 c        18580 g        16016 t
ORIGIN      
        1 tattttattt atattcatgc gttgcatatg aaagtttatg caccacagcg aatacctctc
       61 cattcttagt gatctacctc accttttaaa cgcgcttgcc gaattttgtt atttactctg
      121 acgaaaaatt gtcacgatac acgaaagttt ttcacaggcg gcgactcatg gataaagaac
      181 gcatcattca ggaatttgtg cccggcaaac aggtcacact ggcgcatctt atcgcgcatc
      241 ccggtgagga actggcgaag aaaatcggcg ttccggatgc gggcgcaatt ggcattatga
      301 cgctaactcc cggcgaaacg gcgatgatcg ccggtgattt agcgctgaaa gccgctgatg
      361 tgcatatcgg ttttctcgac cgcttcagcg gtgcattggt gatttatggc tcggtgggcg
      421 cagtagaaga agcgttatca caaaccgtca gcggtttagg tcgcttatta aattatacgc
      481 tttgtgaaat gaccaaaagt taatacgagg cattcatgaa acgaattgcg tttgtgggta
      541 gcgtcggggc aggaaaaaca acgttattta atgcgttgca ggggaattat accctcgcca
      601 gaaaaacaca ggccgtggaa tttaatgata agggcgatat tgatacgccg ggtgaatatt
      661 ttagccatcc ccgctggtat cacgccttaa ttaccacgct acaggatgta gacatgctga
      721 tctatgtcca tggcgcaaat gacccggaaa gtcggttgcc tgccgggttg ctggatattg
      781 gcgtcagcaa acggcaaatc gccgtcatca gtaaaacgga catgccagat gctgacgtcg
      841 ccgcaacgcg aaagttattg cttgagactg gcttcgaaga gccgattttc gagctaaaca
      901 gccacgaccc gcaaagcgtg cagcaactgg tggattatct ggcatctctc accaaacagg
      961 aggaagcagg tgaaaaaact catcacagcg aatgatattc gtgaagcaca cgcgcgcggc
     1021 gaacaggcaa tgtccgtggt tctgcgcgcc agcattatta ccccggaagc ccgtgaagtg
     1081 gcggatctac tgggttttac catcaccgaa tgtgatgaat cgatcccggt aacggcgtcc
     1141 gtgcccgcca gcgtgccagc cgacaaaacc gaaagccagc gcatccgcga aaccatcatt
     1201 gcccagctgc cggaaggcca gtttaccgaa agcctggtcg cacagctgat ggaaaaagtg
     1261 atgaaggaaa aacagtcgct ggagcagggc gcaatgcagc cgagcttcaa atcggtgacc
     1321 ggcaaaggcg gcatcaaagt gattgatggc agtagcgtca agtttggtcg tttcgacggc
     1381 gcagagccgc attgcgtggg cttgactgat cttgtgaccg gagacgacgg cagcagcatg
     1441 gccgccggtt ttatgcagtg ggagaacgca ttcttcccgt ggaccctgaa ctacgacgaa
     1501 atcgacatgg tgctggaagg ggagctgcat gttcgccacg aaggccaaac catgatcgcc
     1561 aaagcaggcg acgtgatgtt tatcccgaaa ggctccagca tcgaatttgg tacgacatcc
     1621 agcgtgaaat tcctgtatgt cgcctggccg gctaactggc aatccctatg aaagatttca
     1681 tcaccgaagc atggctaaga gcgaaccata cgctcagcga aggcgcagag atccatctcc
     1741 ctgcggacag tcgcctgacg ccctctgccc gggagttgct ggaaagccgc catctgcgca
     1801 tcaagtttat tgacgagcag ggccgcctgt ttgttgacga tgaacagcag cagccgcagc
     1861 ccgttcatgg gctgaccagt agcgatgaac atccgcaggc gtgctgcgaa ctgtgtcgcc
     1921 agccggtggc aaaaaagccg gatacgctga ctcacctgtc ggcggaaaaa atggtcgcca
     1981 aaagcgatcc gcgtctgggt tttcgcgcgg ttctcgacag caccattgcg ctggcagtgt
     2041 ggctgcaaat tgaactggcg gaaccgtggc agccgtggct ggcggatatc cgttcgcgtc
     2101 ttggcaacat tatgcgcgcc gatgcgctgg gggaaccgct gggctgccag gcgattgtcg
     2161 ggctttctga cgaagatctg catcggcttt ctcatcagcc gctgcgctat ctcgaccacg
     2221 atcatctggt gccggaagcc agccacgggc gcgatgctgc gttgctcaat ctgctacgca
     2281 ccaaagtgcg ggaaaccgaa accgtagcgg cgcaggtctt tatcacccgc agctttgaag
     2341 tattacgccc ggacattttg caggcgctga accgcctttc gagcacggtc tacgtgatga
     2401 tgatcctgag cgtaacgaag cagccgctaa cggtgaagca gatccaacaa cgactggggg
     2461 aaacgcaatg attattgaac gttgtcgtga actggcgttg cgagcgcccg ccagagtggt
     2521 ttttccggat gcgttagacc aacgtgtgct gaaagccgcg caatatttac atcaacaagg
     2581 tctggcaacg cccattctgg tcgccaatcc gtttgaactt cgtcagtttg cgctcagtca
     2641 cggcgtggcg atggacgggc tacaggtgat tgatccgcat ggcaacctcg caatgcggga
     2701 agaatttgct catcgctggc tggcccgcgc gggcgaaaaa acgccgccgg atgcgctgga
     2761 aaaacttacc gaccctctga tgttcgccgc agcaatggtc agcgccggta aagcggatgt
     2821 ctgtatcgcg ggcaacctct cttccacggc aaatgtgctg cgtgccggat tacgcattat
     2881 cggcttgcag ccaggctgta aaacgctctc ttccattttc ctgatgttgc cacagtacag
     2941 cggcccggcg ttgggctttg ccgattgcag cgtggtgcca cagccgacgg cggcgcagct
     3001 ggcggatatc gcgcttgcca gtgccgaaac ctggcgcgcc atcaccggag aagagccgcg
     3061 cgtggcgatg ctgtcgtttt ccagtaacgg tagcgcccgt cacccctgcg ttgccaacgt
     3121 ccagcaggcg acagaaatcg tccgtgagcg cgcaccaaag ctggtggttg atggcgagtt
     3181 acagtttgac gccgccttcg tgccggaagt ggcggcgcaa aaagcgcctg ccagcccgct
     3241 acagggcaag gccaatgtga tggtttttcc gtcgctggaa gccggaaata ttggttacaa
     3301 aatcgcacaa cgactcggcg gatatcgtgc cgtcgggcca ctgatacaag gacttgccgc
     3361 gccgatgcac gatctctctc gtggttgtag cgtgcaggaa attatcgagc tggcgctggt
     3421 ggcagctgtg ccgcgtcaga cagaagtgaa ccgcgaaagc agtttacaaa cactggttga
     3481 atgaacggtc ccgttctgga ccctgataaa gaggaaagca caatggaagc attaggaatg
     3541 atcgaaaccc ggggcctggt tgcactgatt gaggcttctg acgcgatggt gaaagctgcg
     3601 cgcgtcaagc tggttggtgt taagcagatt ggcggcggcc tgtgtactgc catggttcgt
     3661 ggtgatgttg cagcctgtaa agccgcgacc gatgcaggtg ccgcagcggc acagcgtatc
     3721 ggcgagctgg tatctgtaca cgttatcccg cgtccgcacg gcgacctgga agaagtcttc
     3781 ccgatcggcc tgaaaggcga tagcagcaac ctgtaatcac cctgtgtgac gtcgattcgg
     3841 gcgtcacgct ctctcctttt tcattttacc ttctgcggag ggtaggggga gcttttacct
     3901 gaaatacgcc acggaggcgg gtatgaaact ggcagtcgtc actggacaaa ttgtttgtac
     3961 cgtacgccat cacggactgg cgcatgacaa attgctgatg gtggaaatga ttgatccaca
     4021 aggtaatcct gacgggcaat gcgccgtcgc catcgacaat attggcgcgg gaaccgggga
     4081 gtgggtgtta ctggtgagtg gcagttccgc ccgccaggcg cataaaagcg aaacgtcacc
     4141 ggtcgatctg tgcgtgattg gcattgtcga tgaggtggtg tctggcggtc aggtaatttt
     4201 ccacaaataa ggcagaacat catgaatcaa caggatattg aacaggtggt gaaagcggta
     4261 ctgctgaaaa tgcaaagcag tgacacgccg cccgccgccg ttcatgagat gggcgttttc
     4321 gcgtccctgg atgacgccgt tgcggcagcc aaagtcgccc agcaagggtt aaaaagcgtg
     4381 gcaatgcgcc agttagccat tgctgccatt cgtgaggcag gcgaaaaaca cgccagagat
     4441 ttagcggaac ttgccgtcag tgaaaccggc atgggccgcg ttgaagataa atttgccaaa
     4501 aacgtcgctc aggcgcgcgg cacgccaggc gttgagtgtc tctctccgca ggtgctgacc
     4561 ggcgacaacg gcctgacttt aattgaaaac gcgccctggg gcgtggtggc ttcggtaact
     4621 ccgtccacta acccggcggc aaccgtaatt aataacgcca tcagcctgat tgccgcgggc
     4681 aacagcgtca tttttgcccc gcatccggcg gcgaaaaaag tctcccagcg ggcgattacg
     4741 ctgctcaacc aggcgattgt tgccgcaggt gggccggaaa acttactggt tactgtggca
     4801 aatccggata tcgaaaccgc gcaacgcttg ttcaagtttc cgggtatcgg cctgctggtg
     4861 gtaaccggcg gcgaagcggt agtagaagcg gcgcgtaaac acaccaataa acgtctgatt
     4921 gccgcaggcg ctggcaaccc gccggtagtg gtggatgaaa ccgccgacct cgcccgtgcc
     4981 gctcagtcca tcgtcaaagg cgcttctttc gataacaaca tcatttgtgc cgacgaaaag
     5041 gtactgattg ttgttgatag cgtagccgat gaactgatgc gtctgatgga aggccagcac
     5101 gcggtgaaac tgaccgcaga acaggcgcag cagctgcaac cggtgttgct gaaaaatatc
     5161 gacgagcgcg gaaaaggcac cgtcagccgt gactgggttg gtcgcgatgc ggcgaaaatc
     5221 gcggcggcaa tcggcctgaa cgtgccgcaa gaaacgcgtt tgctgtttgt ggaaaccact
     5281 gcagaacatc cgtttgccgt gaccgaactg atgatgccgg tgctgcccgt cgtgcgcgtc
     5341 gccaacgtgg cggatgccat tgcgctggcg gtgaaactgg agggcggttg ccaccacacg
     5401 gcggcaatgc actcgcgcaa tatcgaaaac atgaaccaga tggcgaacgc cattgatacc
     5461 agcattttcg ttaagaacgg accgtgcatt gccgggctgg ggctgggcgg ggaaggctgg
     5521 accaccatga ccatcaccac gccaaccggt gaaggggtaa ccagcgcgcg gacgtttgtc
     5581 cgtctgcgtc gctgtgtatt agtcgatgcg tttcgcattg tttaaggagt aaccgatggc
     5641 gcacgacgaa caatggctca ccccacgtct gcaaacggcg gcaacgctgt gtaaccagac
     5701 gcctgccgcg acggaatctc cgctgtggct gggggtggat ctgggcacct gcgatgtggt
     5761 gtcgatggtt gttgaccgcg acggtcagcc ggtggcggta tgcctcgact gggccgatgt
     5821 ggtccgcgac ggcatcgtct gggatttctt cggtgcggtc accattgttc gtcgccatct
     5881 cgacactctt gagcagcaat tcggtcttcg ttttagccat gcggcgactt catttcctcc
     5941 aggtacggac ccgcgtattt ccatcaacgt gctggaatct gccgggctgg aagtgagcca
     6001 tgtgctggat gagccaaccg cagtcgcgga tctgctgcaa ctggacaacg ccggtgtagt
     6061 ggatatcggc ggcggcacta ccggcattgc catcgtgaaa aagggcaagg tgacgtactc
     6121 ggcggatgaa gccaccggcg gacatcacat ctctctgact ctcgccggaa atcgtcgtat
     6181 ttcgctggaa gaggcagagc agtacaagcg cggtcatggt gacgagattt ggcccgcggt
     6241 gaaaccggtg tacgaaaaaa tggcggacat tgtcgcccgg catattgaag ggcagggcat
     6301 tactgattta tggctggcgg gcggctcttg tatgcaaccg ggcgtggcgg aactgtttcg
     6361 caaacaattc ccggcgttac aggtgcattt accgcagcac agtttgttta tgaccccgct
     6421 ggcgatcgcc agtagtgggc gagagaaagc ggaggggcta tatgcaaaat gaattgcaga
     6481 ccgcgctctt tcaggcgttc gataccctga atctgcaacg ggtaaaaaca tttagcgttc
     6541 caccggtgac gctttgcggt ccgggctcgg tgagcagttg cggacagcaa gcgcaaacgc
     6601 gtgggctgaa acatctgttc gtgatggcag acagcttttt gcatcaggca gggatgaccg
     6661 ccgggctgac gcgtagcctg gccgttaaag gtatcgccat gacgctctgg ctatgtccgg
     6721 tgggcgaacc gtgcattacc gacgtgtgtg cagccgtggc gcagttgcgt gagtcaggtt
     6781 gtgacggggt gatcgcattt ggcggcggct cggtgctgga tgcggcgaaa gccgtggcgt
     6841 tgctggtgac gaacccggat agcacgctgg cagagatgtc agaaaccagc gttctgcaac
     6901 cgcgcttgcc gctgattgcc attccaacta ccgccggaac cggctctgaa accaccaatg
     6961 taacggtgat tatcgacgcg gtgagcgggc gcaagcaggt gttagcccat gcctcgctga
     7021 tgccggatgt ggcgatcctc gacgccgcat tgaccgaagg tgtgccgtcg catgtcacgg
     7081 cgatgaccgg cattgatgcg ttaacccatg ccattgaagc atacagcgcc ctgaacgcta
     7141 caccgtttac cgacagtctg gcgattggtg ccattgcgat gattggcaaa tcgctgccga
     7201 aagcggtggg ctacggtcac gaccttgccg cgcgcgagag catgttgctg gcttcatgta
     7261 tggcgggaat ggcgttttcc agtgcgggtc ttgggttgtg ccacgcgatg gcgcatcagc
     7321 cgggcgcggc gctgcatatt ccgcacggtc tggcgaacgc catgttgctg ccaacagtga
     7381 tggaatttaa ccggatggtt tgtcgtgaac gctttagtca gattggtcgg gcactgcgaa
     7441 ctaaaaaatc cgacgatcat gacgctatta acgcggtaag tgagctgatt gcggaagttg
     7501 ggattggtaa acgactgggc gatgttggcg cgacatctgc gcattacggt gcatgggcgc
     7561 aggccgcgca ggaagatatt tgtctgcgca gcaacccgcg taccgccagc ctggagcaga
     7621 ttgtcggact gtacgcagcg gcgcaataaa tgccggatgc gacgcttgcc gcgtctgatc
     7681 cggccttcgg gattgcacat gtagggcgga taaggcgttt acgccgcatc cgccaataaa
     7741 taacaactaa cagggagtaa aggcgatggg aattaacgaa atcatcatgt acatcatgat
     7801 gttctttatg ctgatagctg ccgtagacag gatcctgtcg cagttcggcg gttctgctcg
     7861 tttcctcggt aagttcggta aaagtatcga aggatcaggc ggtcagttcg aagaaggctt
     7921 tatggcaatg ggcgctctgg gtctggcgat ggtcggtatg accgcgctgg caccggtact
     7981 ggctcacgta ctcgggccgg taattatccc ggtttacgaa atgctcggcg caaacccgtc
     8041 aatgttcgcc ggaacactgc tggcgtgcga tatgggcggc ttcttcctcg ccaaagagct
     8101 ggcgggcggc gacgtagcag cgtggctata ctctgggtta attctcgggt cgatgatggg
     8161 gccaacgatt gtgttttcca ttccggtggc gctcggcatt atcgaacctt ctgatcgtcg
     8221 ttatctggcg ctcggcgtgc tggcgggcat tgtgaccatt ccgattggct gtattgctgg
     8281 tggtctggtt gctatgtact ccggtgtgca gatcaacggt cagccggtgg aattcacttt
     8341 cgccctgatc ctgatgaaca tgatcccggt gatcattgtc gcgattctgg tggcgctggg
     8401 gctgaaattc atcccggaaa aaatgatcaa cggcttccag atctttgcca aattcctcgt
     8461 tgcattgatc accctcggtc ttgccgctgc ggtagtgaaa ttcctccttg gctgggaact
     8521 gatccccgga ctggatccta tctttatggc ccctggcgat aaacccggtg aagtgatgcg
     8581 cgccattgaa gttatcggtt ctatctcctg cgtgctgtta ggggcgtatc caatggtgct
     8641 gctgctgact cgctggtttg aaaaaccgct gatgagcgtc ggtaaagtac tgaatatgaa
     8701 caacatcgcg gcagccggca tggtggcaac gcttgccaac aacatcccga tgttcggcat
     8761 gatgaagcag atggataccc gcggcaaagt catcaactgc gccttcgccg tttccgctgc
     8821 tttcgccctg ggcgaccact taggcttcgc cgctgccaac atgaacgcca tgatcttccc
     8881 gatgattgtc ggcaagttgc tcggcggcgt aacggcgatt ggcgtggcga tgatgctggt
     8941 gccaaaagaa gacgcgaccg cgactaaaac cgaagcggag gcacaatcgt gaacactcgc
     9001 cagctattga gcgtcggtat cgatatcggc accaccacca cccaggtgat tttctcccac
     9061 ctggaactgg ttaaccgtgc ggcggtgtcg caggtgccgc gctacgaatt cattaaacgc
     9121 gaaattagct ggcaaagccc ggtattcttt acccctgtcg ataaacaggg tggtttaaaa
     9181 gaagcggaac tgaaatcgct gattttagag caatatcagg ctgcgggcat tgcgccggaa
     9241 agcgttgatt ctggtgccat catcatcacc ggtgaaagcg cgaaaacccg caatgctcgc
     9301 ccggcggtga tggcgctctc tcagtcgctg ggcgattttg tcgttgccag cgccgggccg
     9361 cacctcgaat ccgtgatcgc cggtcacgga gccggggcac aaaccctttc tgaacaacgg
     9421 ctgtgtcggg tactgaatat cgacatcggc ggtggcaccg cgaactacgc cctgttcgat
     9481 gccggaaaaa tcagcggcac tgcctgcctc aacgtcggtg gtcgcctgct ggaaaccgac
     9541 agccaggggc gcgtggttta cgctcataaa ccggggcaga tgattgtgga tgagtgcttc
     9601 ggtgcaggca ctgacgcccg ttcgctgacc ggcgcgcagc tggtgcaggt tacccggcgg
     9661 atggcggcgc tgattgtcga agtgattgac ggaacgcttt cgccgctcgc gcaggcattg
     9721 atgcaaaccg gtttgctgcc cgcaggtgtt acgcccgaaa tcattacgct ttctggaggc
     9781 gtgggcgaat gttatcgcca ccagcccgcc gacccgttct gttttgccga tattggccca
     9841 cttctggcaa cggcgctgca tgaccatccg cgcctgcgtg agatgaatgt gcagtttccg
     9901 gcgcaaaccg tacgcgccac ggtgattggc gcgggtgcac ataccctttc gctctctggc
     9961 agcacaatct ggctggaggg cgtacaactg ccgctgcgca atttgccggt ggcgatcccg
    10021 attgatgaaa cggatctggt gagtgcctgg caacaggcgc tgattcaact ggatcttgat
    10081 cccaaaactg acgcgtacgt gctggcgctt cccgcctcgc tgcctgtgcg ttacgccgcg
    10141 gtactgacgg tcatcaacgc gttggtcgat ttcgtcgcgc gttttccgaa tccgcatccc
    10201 ctgctggtgg tggccgggca ggactttggt aaagctctgg gcatgttgtt gcgcccacag
    10261 ctacaacaac tcccgttggc agtcattgac gaagtgattg tccgcgcggg ggactatatc
    10321 gacattggta cgcctctttt tggcggatcg gttgtgccgg tgacggtgaa atcactcgca
    10381 tttccttcct gagggaacga cttatgaaac taaagaccac attgttcggc aatgtatatc
    10441 agtttaagga tgtaaaagag gtgctggcta aagccaacga actgcgttcg ggggatgtgc
    10501 tggcaggcgt tgcagcggca agttcacagg agcgcgtggc ggcaaagcag gtgttgtcgg
    10561 aaatgaccgt agcggacatc cgcaataatc cggtgattgc ctatgaagat gactgcgtga
    10621 cgcggctgat tcaggacgat gttaacgaaa cggcctacaa ccagattaaa aactggagca
    10681 tcagcgaact gcgtgagtat gtgctgagcg atgaaaccag cgtggacgac attgccttta
    10741 cccgcaaagg gctgacctcg gaagtggtcg cggcggtagc gaagatttgc tccaacgcgg
    10801 acctgatcta cggcgcgaag aaaatgccgg taatcaaaaa ggccaatacc accattggta
    10861 ttccgggcac cttcagcgcc cgtttgcagc caaatgacac ccgtgacgac gtgcaaagta
    10921 tcgccgcgca aatctacgaa gggctttcct tcggggtggg cgatgcggtg atcggcgtta
    10981 acccggtgac tgacgacgtg gaaaacttaa gccgcgtgtt ggacaccatt tacggcgtga
    11041 tcgacaaatt caacatccca actcagggct gcgtactggc gcacgtcacc acccagatcg
    11101 aagcgattcg tcgcggcgcg cctggcggac tgattttcca gagtatctgt ggcagcgaaa
    11161 aagggctgaa agagtttggc gtggaactgg cgatgctcga cgaagcgcgc gcagtgggtg
    11221 cagagttcaa ccgtatcgcc ggggaaaact gcctctactt cgaaaccgga caaggctctg
    11281 cgctatccgc tggcgctaac ttcggcgctg accaggtgac gatggaagca cgtaactatg
    11341 ggctggcgcg tcattacgat ccgtttatcg tcaacaccgt ggtcggcttt attgggccgg
    11401 agtatctcta caacgaccgc cagattatcc gtgctggctt agaagatcac tttatgggca
    11461 agctgagcgg catctctatg ggctgtgact gctgttacac caaccacgct gacgctgacc
    11521 agaacctcaa cgaaaacctg atgatcctgc tcgccaccgc aggctgcaac tacatcatgg
    11581 ggatgccgct gggtgatgac atcatgctca actaccagac caccgcattc cacgataccg
    11641 ccactgtgcg tcagttactc aacctgcgtc cgtcaccgga gtttgaacgc tggctggaaa
    11701 gcatgggcat tatggcaaac ggtcgcctga ccaaacgggc gggcgatccg tcactgttct
    11761 tctgatgacg cggagataac acatcatgga tcaaaaacag attgaagaaa ttgtacgcag
    11821 cgtgatggcg tcaatgggac aaacggcccc cgcgccgtca gaagcaaagt gcgccaccac
    11881 caactgtgcg gcaccggtga cctcggaaag ctgtgcgctg gatttaggtt ccgctgaagc
    11941 aaaagcgtgg attggtgttg aaaacccgca tcgcgcagac gtattaacag aactgcgccg
    12001 cagcaccgtg gcccgcgttt gtaccggtcg tgccggtccg cgtccacgta cccaggcgct
    12061 gctgcgtttc ctggccgatc actctcgttc gaaagatacc gtactgaaag aagtgccgga
    12121 agagtgggtg aaagcgcagg gcttgctgga agtacgctct gaaattagcg acaaaaatct
    12181 ctacctgact cgcccggata tgggccgccg cctgtgtgca gaagctgttg aagcgctgaa
    12241 agcacagtgt gttgctaatc cggacgtaca ggtcgttatt tctgatggcc tgtcaactga
    12301 tgccatcacc gtcaactacg aagagatcct gccgccgctg atggcgggcc tgaaacaggc
    12361 cgggctgaaa gtcggcacgc cattctttgt tcgttatggt cgcgtgaaga ttgaagatca
    12421 gatcggtgag atcctcggcg cgaaagtggt gatcctgctg gtgggggaac gtccggggtt
    12481 gggtcagtca gaaagcctct cctgttacgc cgtttactcg ccgcgtatgg cgaccaccgt
    12541 tgaggccgat cgcacctgca tctctaacat tcaccagggc ggcacgccgc cggttgaagc
    12601 cgcagccgtc attgtggatt tggcgaaacg tatgctggag cagaaagcat ccggcatcaa
    12661 catgacccga taaggaggca tcatgccagc tttagatttg attcgaccgt cggtaaccgc
    12721 catgcgggtg attgcctccg ttaacgctga atttgcgcgt gaactaaaat tgccgccgca
    12781 tattcgtagc ctcgggctga tttctgctga ttccgatgac gtcacctaca ttgccgctga
    12841 tgaagcgacc aagcaggcga tggtggaagt ggtatatggt cgctcgctgt atgcgggcgc
    12901 tgcacacggc ccgtcaccga ctgccggtga agtgctgatt atgcttggtg ggccaaaccc
    12961 ggcggaagtg cgtgccggtc tggatgcgat ggttgcacat attgaaaatg gtgcagcatt
    13021 ccagtgggcc aatgacgcag aaaacaccgc cttcctggcg catgtggttt cgcgtaccgg
    13081 ttcttatctc tcatcaaccg ccgggatcac gcttggcgat ccgatggcgt atctggtggc
    13141 accgccgctg gaagcgacct atggcattga tgcagcgttg aaatctgccg acgtacagct
    13201 ggtgacctat gtcccgccac cgtctgaaac caactactcg gcagcatttt taaccggtag
    13261 ccaggccgcg tgtaaagcag cctgtaacgc ctttaccgat gcagtgctgg aaatcgcgcg
    13321 taatccaatc cagcgtgcgt aacggaggtt gccgatgatc aatgcactgg gattgctgga
    13381 agtggacggc atggtcgccg cgatagatgc agcggatgcc atgctcaaag cagctaacgt
    13441 tcgtctgctc agtcacgaag tgcttgaccc tggtcgctta acgctggtgg tggaaggcga
    13501 tctggcggcg tgtcgtgcgg cgctggacgc aggttgtgct gccgcgatgc gtaccgggcg
    13561 tgtcatcagc cgcaaggaga tcggtcggcc agacgatgac acccagtggc tggttactgg
    13621 ctttaaccgc cagccgaagc aacccgtaag ggaacccgac gcgccagtta tcgtcgcgga
    13681 atctgctgac gagttgttgg cgctgttaac atcagtacgt cagggaatga cggcaggaga
    13741 agtggctgcc cactttggct ggccgctgga aaaagccaga aatgcgctcg aacagctctt
    13801 ttctgccggg acgttacgta aacgcagtag tcgttatcgt ctcaagcccc attaacctgt
    13861 cggaggtgcc gggtgtccta caacacccgg cattaacatc atgaaaaaga cccgtacagc
    13921 caatttgcac catctttatc atgaaccctt acccgaaaac ctgaagctca cgccgaaggt
    13981 cgaagtggat aatgttcatc aacgacagac aacggatgtc tatgaacatg ctttaacgat
    14041 taccgcctgg cagcagattt acgatcagct gcatccgggc aagtttcatg gtgaatttac
    14101 ggaaattcta ctcgatgata ttcaggtttt tcgtgaatac accggtctgg cgctgcgtca
    14161 gtcgtgcctg gtctggccga actcgttctg gtttggcatt ccggcgacgc gcggtgagca
    14221 gggatttatc ggttcgcaat gtctgggaag cgcggaaatc gccacccgcc ctggtggcac
    14281 tgaatttgaa ctgagcacgc cggatgatta cacgatcctg ggcgtggtgc tttctgaaga
    14341 tgtcatcacc cggcaggcta actttttgca taacccggat cgggtattac atatgctgcg
    14401 tagccagtcg gcgctggaag tgaaagagca gcataaagcc gcgctgtggg gctttgtcca
    14461 acaggcgctg gcgacgtttt gcgagaaccc ggaaaatctc catcagcctg cagtgcgaaa
    14521 agtgctgggg gataatttgc taatggcgat gggggcgatg ctggaagacg cgcaaccaat
    14581 ggtgacggcg gaaagcatca gtcatcagag ttaccgtaga ttactttccc gcgcccgtga
    14641 atatgtgctg gaaaatatgt ctgagccggt gacggtgctg gacttgtgta atcaactgca
    14701 tgtcagtcgc cgcacgctac aaaacgcgtt tcacgctatt ttaggcattg gcccaaacgc
    14761 gtggctgaaa cgcattcgcc tgaacgccgt acgccgcgaa ctgataagcc cgtggtcgca
    14821 aagcacaacg gtaaaagacg ccgccatgca gtggggattc tggcatctgg ggcaatttgc
    14881 cacggattac cagcagctgt ttgccgagaa gccgtcgttg acgttgcatc agcggatgcg
    14941 ggaatggggg tgagggagtt acacccaatc cctgacctta ataaactcac ttaacgccgc
    15001 ttctgggctg ccatcttttg gctgataatc atactcccag cgtaccagtg gcggcattga
    15061 catcaggatc gactcggtgc gcccgccagt ttgcaggcca aacagagtgc cgcgatccca
    15121 gaccagattg aactcgacat aacgaccgcg acggtagagc tgaaaattgc gctcgcgctc
    15181 gccgtaggcc atcgctttac gtcgctctac aattggtaaa taagcgtcgg tgtagccttt
    15241 gcctaccgcc tgcataaagg caaaacagtg gtcgaaatct ggcgtgttca gatcatcaaa
    15301 gaacagcccg ccaataccgc gctgttcgtt gcgatgtttg aggtagaagt aatcgtcgca
    15361 ccactttttg taacggggat aaacgtcttc accaaatggc aggcacaggt cacgggcggt
    15421 gcggtgccag tgaatggcgt cttcttcaaa accatagaaa ggggttaaat cgaagccgcc
    15481 gccaaaccac cagacgggct ctgcacccgg tttttcggca ataaaaaaac gcacattcgc
    15541 gtggctggtg ggaacatacg ggttatgcgg atgcactacc agtgaaacgc ccatcgcctc
    15601 gaaactgcgc ccggcaagct ccgggcgatg agcggtggcg gaagcaggca tcgcctcgcc
    15661 gtggacgtga gaaaagttga cgcctgcctg ttcgaaaaca ccaccattac gcaacacccg
    15721 actacgcccg ccgccgccag cttcgcgctg ccaactatct tcgacaaatt ctgcgccatc
    15781 gacggcggtc agctgctgac aaatcgtatc ctgaaggttg agcagaaact gtttaacctg
    15841 gtgtgcgtcg ggtttcataa cttatcgctt tttcgaatgt gctttctggt tgtcgaacca
    15901 gtggaaataa ctgatcacgc cttcagcaat cgctgtggcg attttctgac gaaacgccgc
    15961 cgtgcctaac agccgctctt cttccgggtt ggtgataaac gaggtttcca ccagcaccga
    16021 aggaaccgac ggcgatttca acaccacaaa cgcggcttgt tcggtgttgc ggctgtgcag
    16081 tttatgcacc ggcttaatct ttttcagaat atgcgagccg agcatcaggc tgtttttaat
    16141 agtatcggtt tgcaccagat caaacagcac ttgctgcaat aggtgatcct tgtcagtcgc
    16201 ctttttaccg gcaacttcat cggcgcggtt ttcgcgttca gacaggtatt tcgccattgc
    16261 gctacttgcc ccacggttag agagggcaaa taccgaagca ccggcagctt tcgggttggt
    16321 aaagccatcg gcatgaattg acataaacag atctgcgcca tgtttatggg cgatttcaac
    16381 gcgatcgtaa agtgggataa acgtatcgcc agaacgcgtt aaacgcgcat caatcccatg
    16441 attacgcaaa atggaacgga cgtttttagc aatcgccagc accacatgtt tttctttcga
    16501 accgttgcgt ccgatcgctc cggtatcaat tccgccgtgg cctggatcga gaacaacgac
    16561 acgtttgccg ccagattttt tggctttcgg cttgctgtgt ccgttgctgg tttttaaagg
    16621 ttcgtctttg gcgatggctt gcgacattcc tgacaacgtc agggcagcca aaccggcttt
    16681 cagcacctgg cggcgcgaag tgagtgtttt tagtggttta aaagtgctca tacggcctga
    16741 gttgtaataa taaagttcca gatgttatat cgtatcgcgt aatccgttac gacggtttga
    16801 tgttgagaat tgttttactt ttcatttcaa tagttgacaa ctccccatta tgccactttt
    16861 tcaaccgatt ttcgtcagat attggctaat tcgaccgttc acgccataat cagcctttta
    16921 acccgcaaaa aggtaacgaa taccatggag atacgcgtat ttcgccagga agatttcgaa
    16981 gaggtcatca ccctttggga gcgttgcgac ttgctgcgtc cgtggaacga tccggaaatg
    17041 gacatcgagc gtaagatgaa ccatgacgtc agtttgtttt tggtcgctga ggtaaacggt
    17101 gaagtggtcg gaacggtgat gggcggttat gacgggcatc gcgggtctgc ttattatctt
    17161 ggcgtgcatc cagagtttcg tgggcgtggg attgccaatg cgttgcttaa tcggctggag
    17221 aaaaagctga ttgctcgtgg ctgcccgaaa attcagatca atgtgccgga agataacgac
    17281 atggtgctcg gaatgtatga acgcctggga tatgaacacg ccgacgtgct gagtctgggt
    17341 aagcgtttga ttgaagatga agagtactga gttccatcct gtccattatg atgcgcacgg
    17401 acgcctgcgt ttacccttgc tcttctggct tgtgctattg cttcaggcgc gaacctgggt
    17461 gctgtttgtc attgccggtg cgtcgcgcga gcagggtact gcgctgctaa atctgtttta
    17521 tcccgatcac gataatttct ggctggggct gattccaggc attccggcgg tgctggcgtt
    17581 tttgttgagc ggtcggcggg ctacatttcc tcgcacttgg catgtgctct attttctgtt
    17641 gctgttggcg caggtggttt tactttgctg gcaaccgtgg ctgtggctga acggtgaatc
    17701 cgttagcggt atcggtctgg cgctggtagt ggcggatatt gtggcgttaa tctggctgct
    17761 gaccaatcga cgtttacgcg cttgttttaa tgaagtaaaa gaataacggc actttttggt
    17821 gaatttgcac tccaagcaac gttattgaat aaccaaagga agtgacatga aatcgctgcg
    17881 tttaatgtta tgcgctatgc cgttgatgct gaccggctgt tccacgatgt cgtcagttaa
    17941 ctggtcggcc gctaacccgt ggaactggtt tgggtcgtcc accaaagtga gcgagcaggg
    18001 cgttggtgaa ttaacggcgt ccacaccact gcaagaacaa gccattgccg atgcgcttga
    18061 tggcgattat cgcctgcgca gcggaatgaa aaccgcgaac ggcaacgtgg tgcgcttttt
    18121 tgaagtgatg aagggcgaca acgtggcgat ggtgattaac ggcgatcaag gcacgatcag
    18181 tcgcattgac gtgctggata gcgatattcc tgctgacacc ggtgttaaaa tcggtacacc
    18241 gtttagcgac ctttacagca aagcatttgg caattgccaa aaagctgatg gtgatgataa
    18301 tcgtgccgtc gaatgtaaag ccgaaggcag tcaacatatt agctaccagt tcagcgggga
    18361 atggagtggt cctgaagggt taatgccttc ggacgatacc ctgaaaaact ggaaagtcag
    18421 taaaattatc tggcggcgtt aatttgcgtc tgaacaaacc gccgccgcga aaaaacacgt
    18481 aaaatagcgc tcaacaatgc cacggattgc gtggcattat tattttcagg aggaacaatg
    18541 tctcaggttc agagtggcat tttgccagaa cattgccgcg cggcgatttg gatcgaagcc
    18601 aacgtgaaag gggaagttga cgccctgcgt gcggccagta aaacatttgc cgacaaactg
    18661 gcaacttttg aagcgaaatt cccggacgcg catcttggtg cggtggttgc ctttggtaac
    18721 aacacctggc gcgctctgag cggcggcgtt ggggcagaag agctgaaaga ttttccgggc
    18781 tacggtaaag gccttgcgcc gaccacccag ttcgatgtgt tgatccacat tctttctctg
    18841 cgtcacgacg taaacttctc tgtcgcccag gcggcgatgg aagcctttgg tgactgcatt
    18901 gaagtgaaag aagagatcca cggcttccgt tgggttgaag agcgtgacct gagcggcttt
    18961 gttgacggta cggaaaaccc ggcgggtgaa gagacgcgtc gcgaagtggc ggttatcaaa
    19021 gacggcgtgg atgcgggcgg cagctatgtg tttgtccagc gttgggaaca caacctgaag
    19081 cagctcaacc ggatgagcgt tcacgatcag gagatgatga tcgggcgcac caaagaggcc
    19141 aacgaagaga tcgacggcga cgaacgtccg gaaacctctc acctcacccg cgttgatctg
    19201 aaagaagatg gcaaagggct gaagattgtt cgccagagcc tgccgtacgg cactgccagt
    19261 ggcactcacg gtctgtactt ctgcgcctac tgcgcgcgtc tgcataacat tgagcagcaa
    19321 ctgctgagca tgtttggcga taccgatggt aagcgtgatg cgatgttgcg tttcaccaaa
    19381 ccggtaaccg gcggctatta tttcgcaccg tcgctggaca agttgatggc gctgtaagcg
    19441 tttctgattc attgattaaa ggccaggcag taacattact gactggcctt tttattactt
    19501 ttgctttaac gccgcataca cctgatcaac tacccaacca tacgttgcaa tcggcagctg
    19561 accgctttcg aacatattgg gattcttttg cggatcggca accggcgaat gtggcttgtt
    19621 gcttaacatc acaatcgcca tatgattcac cggatcgata acggtcaccg ttccggtcca
    19681 gccagtgtga ccgtaggttt gcgggcttgc cagcgtgcca aacgtcggcg tcatggtggc
    19741 attaccattc acgcgccagc cgaggccaaa agtggcatct tccttagagc tggtggtgaa
    19801 catcttcacc gtttccgcac tgaacagctg cacatcgcca tagcccccgc cgttcagcat
    19861 cgtttgcatt aacaccgcaa tatcgccggt attggaaaac aaacctgcgt gcccggaaac
    19921 gccgcccatc gaataaaagg ctttttcatc gtgcacctga ccccagagag tggaggtgcg
    19981 gatattcggg aaatggatca cgccatcgcg ggtattgccg ttcaattccg tggcggcaat
    20041 ttgctgcggt ttaaagcctt tcagcagcgg gttaaatacc gtatgtgtca ggccgagcgg
    20101 gcgataaatc gactcttcaa catagcggtc aagcggctga ccggtgaccg actcgacgat
    20161 aaatccaagc agcatataat cgacatcact gtaaatatgc ttgctgccgg gctgatactc
    20221 cagcggcgtg cgcttgatca tctccagcgt ctggccttta tcctgggaat ataacgcgcc
    20281 cgcgaccgct ttattcggat attgtgggtc cgccgggaaa ccgccgctgt gatgcagcag
    20341 gtcagaaatc cgcagcgtgt ttttgccttt gatggtgtca tttggactat cggcaaaccc
    20401 cggaatatat ttcgcaatcc gatcgtcagg atgcagtttg ccttcgctca tcagcttttg
    20461 cagggcgaag ttcgtggcgt acattttggt gtttgaggcc aggtcataca gcgtcccggt
    20521 ggtggctttg acaggctgtt ccatcaacac gctgccatcg tactttttcg ccgctcccca
    20581 ggctttgcga tacacaatct gattatcttt aatgatcagc aggtttacgc cgggataacc
    20641 ggcgtccact tgctggctaa tccagcgatc catctggtta agccgttcga cgttgaaccc
    20701 tgctttctct ggcgaacttt ctgtcagaac agggtatttt gcggcgctga cgctacaact
    20761 aacagccagc agagaaagat agagcattgt ccgtttcatg atatcagtca agattgacgt
    20821 tacggcagcc aaagagcgtg gtgaaaataa acccgcaaac ccatgccacc agaatcccgc
    20881 cagcataaac cgccattgcc ggaaggatgc cttgtgcgga agtcatcagc ggcagcgcca
    20941 ccagaccaga cggcccaaag gcgctgttta agcccatcgg cagaccccac caggctatca
    21001 ggccgataaa caaaccgccc gctgcgccgc ctaaacaggc ggtaataaac ggtttcatgc
    21061 ggggcagggt gacgccgtaa atcagcggtt cgccaacgcc cagcagacca ggaataatcg
    21121 ccccgcggac ctgactgcgt aatgcactgt gcggttgcgc ccgccagtag agtgccagcg
    21181 ccgcgcccac ctggcccgcg cctgccattg aaaggatggg aaataagctg ttgaatccct
    21241 gactgtccat taacgcgagg taaacaggaa taaacccctg atgcacgcca aacaccacgg
    21301 cgatcaggaa cagcccggct aaaaccgcac aaccgagcgg attactgttc aggtgcataa
    21361 acagccacga catgccttcg aataaccagc cacccagcgg cattatgatc aggtacgcca
    21421 gcgtagcggt gatcagcaga gtgattaacg aggtcagcag catgtcgaga tcgtccggca
    21481 taaagcggcg caccatgcct tcgatgcggg cgcaggccca cgcggcaatc aacacgccga
    21541 taatattgcc gcgcggatcg atgggcagac caaagaaatc gtgaaatccg gcgtagtaac
    21601 ccgtggttgc agcggggtta taaccgagca aaaagagcgc cgcgataatt gcgccattta
    21661 cgcccgtgcc gccaaatgcc tgggcggcgt tatagcccac cagaatcacc aggaaggtga
    21721 acaggccttt gctaaacacc ttcataaaat tcagcgcatc gggtagtgtt ccctgagcat
    21781 ctgccggaac gtgcatcacc gtggcaatta acgtcgctat ccccagcagc agaccggcgg
    21841 caataaaacc ggggatcagc ggcgtgaaga tggtggcgaa tttggcgaga aattgttgca
    21901 cgccggaggt ttgtttggct tttaactgac gtttgttctg ggcggcgatt tctgcggcat
    21961 cctgtaccgg tgcctcgccc agcagctcgc tcatcgcttt tgcggcacga tgcgctttac
    22021 caggcccaaa aacgacctgc acctggtcgc tggtcaaaat gacgcccttc acgccttcca
    22081 gcgttttgat attgggatca accagtgaac tgtcatgtac acccagacgc aggcgcgtca
    22141 tacagttacc acaactggcg atatttcccg gtccgccgac acgggtaaga atggtgttca
    22201 gaagttcact gctgatctct ttggccatgg gttattcctt gtctaaaacc tgacgaataa
    22261 agccgccgtg ttgatccagg cgttttttag cttctgcggc atcgagattt ttcagcacca
    22321 tcacaatggc cgttttacag ttgcgctcgc aggcaattaa cgccgcttcc gcttgttcgg
    22381 cattacatcc ggtggcgttt ttaacgatat tgacctggcg cacatgcagt ttttcgttgg
    22441 tggcgaccac atcgaccatc aggttgccga acactttgcc agatttaatc atcagcccgg
    22501 tggaaagcat attgagcacc agtttctgcg ctgtgcctgc tttcattcgc gaagaaccag
    22561 tgaccacttc ggcacctaca atcggtgtaa tggcaaactc ggcggtggtg gaaacggcac
    22621 tccccggatt acaggaaatt cccactgtgc ggcagccgag ctggcgtgcg tattccagtc
    22681 cggcaatcac atacggcgtg cgaccgctgg cagcaatgcc aaccaccaca tcctgtgccg
    22741 ttaaattaat atttttcaga tcgttaacac caccttcccg gctatcttca gcgccttcca
    22801 ccgcgtgctg aatggcatat tcgcctccag caatcaaacc aaccaccaga cccggtttca
    22861 cgccgtaggt gggcggacat tcgctggcat ccagaatccc cagacgaccg gatgttcccg
    22921 caccgagata aatcagacga ccgccgccgc tgacctgggc gtggataaca tcgatcgccg
    22981 cggcgatatc cggcaggacg cgctcaacgg caagcggtac ggttttatct tcatcgttga
    23041 taatccggca catttccagc gtcgatacgc ggtcaatttc agccgaggcg gtgttcgagc
    23101 cttcagtaat catcttttct agttgcatcg gtggtgacct tactatttac gatcaaataa
    23161 ttgcagatgt atggaatcat atatcccgaa ttgacagact taaaggaatc attgagtcta
    23221 cactcgcaga gtgtgaagag cgtcataaga acttaagcgg aatttatgct gccagcccag
    23281 gagagaggaa gatgttgtac ctgacgaaaa taagcaatgc ggggagtgaa ttcaccgaaa
    23341 acgagcaaaa aatcgctgac tttctgcagg ccaacgtgag tgagctgcaa tccgtttctt
    23401 cacggcagat ggcgaaacag ctcggcatta gccagtcgag catagtgaaa tttgcccaaa
    23461 aactcggcgc gcaaggattt actgaattgc gtatggcgtt aataggcgaa tacagtgcca
    23521 gccgggagaa aacgaatgcc acggcgctgc acctgcacag ttcgattacc agtgatgatt
    23581 cgctggaagt gattgcccgc aaattgaatc gcgaaaaaga gctggcgctg gagcaaacct
    23641 gttcgttgtt cgactacgcg cggctgcaaa aaatcattga ggtcatcagt aaagcaccgt
    23701 ttatccagat aacgggcctg ggcggatcgg cgctggtggg gcgcgatctg tcgttcaaac
    23761 tgatgaaaat tggctatcgc gtggcctgcg aagccgacac gcacgtacaa gccaccgttt
    23821 cccaggcgtt gaaaaaaggc gatgtacaaa tcgctatctc ttacagcggc agtaaaaaag
    23881 agattgtctt atgcgcagaa gcggcacgaa agcagggggc aacggtgatt gccattactt
    23941 ctctggctga ttctccgctg cggcggctgg cgcatttcac gctcgatacc gtttccggtg
    24001 aaaccgaatg gcgtagctcg tcgatgtcta cccgcacggc gcaaaattct gttaccgatt
    24061 tactgtttgt tggtcttgtg caactcaatg atgtggagtc attgaaaatg attcagcgca
    24121 gcagtgagct aacacaacgc ctgaaatgat gcataaagca gcgactggat tgagattttc
    24181 ctgaattagt gagctgatcc gcagcaatat tttgtttatc ctgtattttc agagggaatg
    24241 gagtgtaacg ctctgtatta acaaggagag cattaaaatg ggtaaactca cgggcaagac
    24301 agcactgatt acgggcgcat tgcagggaat tggcgaagga attgccagaa cttttgcgcg
    24361 tcatggcgca aacctaatct tgctggatat ctcccctgag atcgaaaagc tggcggacga
    24421 actgtgtggt cgtggtcatc gctgtacggc ggttgtcgcc gatgtgcgtg acccggcgtc
    24481 ggtagccgca gctatcaaac gcgcgaagga aaaagaaggg cgcattgata tcctggtgaa
    24541 taacgcaggc gtttgtcgtc tgggcagttt cctcgatatg agcgatgacg atcgcgattt
    24601 ccatattgac atcaatatta aaggcgtatg gaacgtcacg aaggcggtgc tgccggagat
    24661 gattgcccgc aaagatggtc gcattgtgat gatgtcttcg gtcactggcg atatggtggc
    24721 cgatcctggc gaaacggcgt acgccttaac gaaagcggcg attgttggcc tgacaaaatc
    24781 gctggcggtg gagtacgcgc agtctggtat tcgcgttaac gccatttgcc cgggatacgt
    24841 gcgcacacca atggcggaaa gcattgcccg ccagtcgaac ccggaagatc cagagtcggt
    24901 gctgactgaa atggcgaaag caatcccgat gcgtcgcctc gccgatccgc tggaagtcgg
    24961 cgaactggcg gccttcctcg catcggatga atccagctat ttaaccggta cacagaatgt
    25021 gattgatggc ggcagcacac tgccggagac ggttagcgtc ggtatctgat tcacctctgt
    25081 ttcctccctg catttgtggg gaggatttcg ttttaaaccc ggttcttatt cccttttcaa
    25141 cttccaaatc accaaacggt atataaaacc gttactcctt tcacgtccgt tataaatatg
    25201 atggctatta gaaagtcatt aaatttataa gggtgcgcaa tggccgttaa cttactgaaa
    25261 aagaactcac tcgcgctggt cgcttctctg ctgctggcgg gccatgtaca ggcaacggaa
    25321 ctgctgaaca gttcttatga cgtctcccgc gagctgtttg ccgccctgaa tccgccgttt
    25381 gagcaacaat gggcaaaaga taacggcggc gacaaactga cgataaaaca atctcatgcc
    25441 gggtcatcaa aacaggcgct ggcgatttta cagggcttaa aagccgacgt tgtcacttat
    25501 aaccaggtga ccgacgtaca aatcctgcac gataaaggca agctgatccc ggccgactgg
    25561 cagtcgcgcc tgccgaataa tagctcgccg ttctactcca ccatgggctt cctggtgcgt
    25621 aagggtaacc cgaagaatat ccacgattgg aacgacctgg tgcgctccga cgtgaagctg
    25681 attttcccga acccgaaaac gtcgggtaac gcgcgttata cctatctggc ggcatggggc
    25741 gcagcggata aagctgacgg tggcgataaa gccaaaaccg aacagtttat gacccagttc
    25801 ctgaaaaacg ttgaagtgtt cgataccggc ggtcgtggcg caaccaccac ttttgccgag
    25861 cgtggcctgg gcgatgtgct gattagcttt gaatcggaag tgaacaacat ccgtaaacag
    25921 tatgaagcac agggctttga agtggtgatc ccgaaaacca atattctggc ggaattcccg
    25981 gtggcgtggg tcgataaaaa tgtgcaggcc aacggtacgg aaaaagccgc aaaagcctac
    26041 ctgaactggc tctacagccc acaggcgcag accatcatca ccgactatta ctaccgtgtg
    26101 aataacccgg aagtcatgga caaactgaaa aacaaattcc cgcagaccga gctgttccgc
    26161 gtggaagaca aatttggctc ctggccggaa gtgatgaaaa cccacttcac cagcggcggc
    26221 gagttagaca agctgttagc ggcggggcgt aattaatgtt tgcagtttca tcaagacgcg
    26281 tgctgccggg ctttacctta agcctcggca ccagtctgct gtttgtgtgc ctgattttgc
    26341 tgctgccgct ctccgcgctg gtgatgcagc tggctcagat gagctgggcg cagtactggg
    26401 aggtgatcac caacccgcag gtggtcgcgg cctacaaagt aacgctgctg tcggcgtttg
    26461 tggcatcgat ttttaacggc gttttcggtc tgctgatggc gtggatccta acccgctatc
    26521 gcttcccagg ccgcacgctg cttgatgcgc tgatggattt accctttgcg ctgccaacgg
    26581 cagtcgccgg gttaacgcta gcctcgctct tttctgtaaa cggtttttac ggtgaatggc
    26641 tggcgaagtt tgatatcaaa gtcacctata cctggctggg gattgcggtg gcgatggcct
    26701 ttaccagcat tccgtttgtg gtacgtaccg tgcagccggt gctggaagag ttaggcccgg
    26761 aatatgaaga agcggcggaa acgcttggtg caacgcgctg gcagagtttc tgcaaagtgg
    26821 tgctgccgga gctttctccg gcgctggtgg cgggcgtggc gctgtcgttt acccgtagtc
    26881 ttggtgaatt tggcgcggtg atttttatcg ccggaaatat cgcgtggaag acggaagtga
    26941 cgtcgctgat gatttttgtg cgcttacagg agtttgatta cccggcagcg agcgcgattg
    27001 cttcggtgat cctcgcggca tctctgctgc tgctgttctc aattaacact ctgcaaagtc
    27061 gctttggtcg gcgtgtggta ggtcattaat ggcggaagtt acccaattga agcgttatga
    27121 cgcgcgcccg attaactggg gcaaatggtt tctgataggc atcgggatgc tggtatcggc
    27181 gttcatcctg ctggtgccga tgatttatat cttcgtacag gcgttcagca aagggctgat
    27241 gccggtttta cagaatctgg ccgatccgga catgctacac gccatctggc tgacggtgat
    27301 gatcgcgctg attgccgtac cggtaaacct ggtgttcggc attctgctgg cctggctggt
    27361 gacgcgcttt aacttccctg gacgccagtt actgctgacg ctactggaca ttccgtttgc
    27421 cgtatcgccg gtggttgccg gtctggtgta tctgctgttc tacggctcta acggcccgct
    27481 gggcggttgg ctggatgaac ataatctgca aattatgttc tcctggccgg gaatggtgct
    27541 ggtcaccatc ttcgtgacgt gtccgtttgt ggtgcgcgaa ctggtgccgg tgatgttaag
    27601 ccagggcagt caggaagacg aggcggcgat tttgcttggc gcgtctggct ggcagatgtt
    27661 ccgtcgtgtc acattgccga acatccgctg ggcgctgctt tatggcgtag tgctgaccaa
    27721 cgcccgcgcg attggcgagt ttggcgcggt gtcggtggtt tccggctcga ttcgcggcga
    27781 aacactttcg ctgccgttac agattgaatt gctggagcag gactacaaca ccgtcggctc
    27841 ctttactgcc gccgcgctgt tgacgctgat ggcgattatc accctgtttt taaagagtat
    27901 gttgcagtgg cgcctggaga atcaggaaaa acgcgcgcag caggaggaac atcatgagca
    27961 ttgagattgc caatattaag aagtcgtttg gtcgcaccca ggtgctgaac gatatctcac
    28021 tggatattcc ttcaggtcag atggtcgcgt tgctggggcc gtccggttcc gggaaaacca
    28081 cgctgctgcg cattatcgcc gggctggagc atcaaaccag cgggcatatt cgcttccacg
    28141 gcaccgacgt cagccgcctg cacgcgcgcg atcgcaaggt cggtttcgtg ttccagcatt
    28201 acgcgctgtt ccgtcatatg acggtgttcg acaatatcgc ttttggcctg acggtgctgc
    28261 cacgtcgcga gcgcccgaat gccgcagcca tcaaagcgaa agtgacaaaa ttgctggaga
    28321 tggtgcagct tgctcatctg gcagatcgtt atccggcaca gctttccggc ggccagaaac
    28381 agcgcgtggc gctggcgcgc gcgctggctg tagaaccgca aattctgctg cttgatgaac
    28441 cgtttggcgc gctggatgcg caggtgcgta aagagctgcg tcgctggctg cgtcaactgc
    28501 atgaagagct gaaattcacc agcgtgttcg tgacccacga ccaggaagag gcgaccgaag
    28561 tagccgatcg tgtagtggtg atgagtcagg ggaatattga acaggctgat gcgccgaatc
    28621 aggtatggcg cgaaccagcg acccgttttg tactcgaatt tatgggcgaa gtgaaccgcc
    28681 tgcagggaac cattcgcggc gggcagttcc atgttggcgc gcatcgctgg ccgctgggct
    28741 acacacctgc gtatcagggt ccggtggatc tcttcctgcg cccgtgggaa gtggatatca
    28801 gccgccgtac cagtctcgat tcgccgctgc cggtacaggt actggaagcc agcccgaaag
    28861 gtcactacac ccaattagtg gtgcagccgc tggggtggta caacgaaccg ctgacggtcg
    28921 tgatgcatgg cgacgatgcc ccgcagcgtg gcgagcgttt attcgttggt ctgcaacatg
    28981 cgcggctgta taacggcgac gagcgtatcg aaacccgaga tgaggaactt gctctcgcac
    29041 aaagcgcctg ataggttgag tgaatgttaa acgcccggag gcgcttcccg cgatccgggc
    29101 tttttaatgg caaggtttgt aacctgtaga cctgataaga cgcgcaagcg tcgcatcagg
    29161 caacaccacg tatggataga gatcgtgagt acattagaac aaacaatagg caatacgcct
    29221 ctggtgaagt tgcagcgaat ggggccggat aacggcagtg aagtgtggtt aaaactggaa
    29281 ggcaataacc cggcaggttc ggtgaaagat cgtgcggcac tttcgatgat cgtcgaggcg
    29341 gaaaagcgcg gggaaattaa accgggtgat gtcttaatcg aagccaccag tggtaacacc
    29401 ggcattgcgc tggcaatgat tgccgcgctg aaaggctatc gcatgaaatt gctgatgccc
    29461 gacaacatga gccaggaacg ccgtgcggcg atgcgtgctt atggtgcgga actgattctt
    29521 gtcaccaaag agcagggcat ggaaggtgcg cgcgatctgg cgctggagat ggcgaatcgt
    29581 ggcgaaggaa agctgctcga tcagtttaat aatcccgata acccttacgc ccattacacc
    29641 actaccgggc cggaaatctg gcagcaaacc ggcgggcgca ttacccattt tgtctccagc
    29701 atgggaacaa ccggcactat caccggcgtt tcacgcttta tgcgcgaaca atccaaacca
    29761 gtaacgattg ttggcctgca gccggaagaa ggcagcagta ttcccggcat tcgccgctgg
    29821 cctgcggaat atctgccggg gattttcaac gcttctctgg tggatgaggt gctggatatt
    29881 catcagcgcg atgcagaaaa caccatgcgc gaactggcag tgcgggaagg aatattctgt
    29941 ggcgtcagct ccggcggcgc ggttgccgga gcactgcggg tggcaaaagc taaccctggt
    30001 gcggtggtgg tagcgatcat ctgcgatcgt ggcgatcgct acctttccac cggggtgttt
    30061 ggggaagagc attttagcca gggggcgggg atttaagatt attgcgcagg caccgtttta
    30121 tccgtctgcg caattagcgc atgtaaaaaa ggctgtgcgt tctcatcgct cttaccgggg
    30181 atcttcacaa tatacggctt cccggtaatc gatgacgacg aagcaacctt atcaataaac
    30241 tgctcggcag tgtcaatgcg gttacgggta ttgcccagct tcagacgcag atgagaaacc
    30301 gcttcatcgc aggtatgttc atcaccgttg cgcacaaata tcaaatcctt tttctgtgct
    30361 aatccctcca gcatggcgtt gatgcgggct tcttcatggg cagttaactt cgcgtaagcg
    30421 gggagtgtca ttagtagtgt aatgaccaga caaatgattt tcttcattga attaccttat
    30481 ccttgttttg tgatagccga tttgactgcc agaatcaggt aaagtttcgg ttggaatacg
    30541 atgaggatca tcggcaagga gaaaaaatta aatgagtagt ttgttgttgt ttaacgataa
    30601 gagcagggcg ctgcaggcgg atatcgtcgc cgtgcagtcg caggtggttt acggcagcgt
    30661 gggcaacagc attgccgtgc ctgctatcaa acagaacggt ctgaatgttt ttgccgtgcc
    30721 gacggtattg ctgagcaata cgccgcatta tgacactttc tacggtggtg cgattccgga
    30781 tgaatggttt agcggttatt tgcgtgcgct tcaggagcgt gatgcgctgc gccagctgcg
    30841 cgctgtaacc acgggctata tgggaacggc atcgcaaatc aaaatccttg ccgagtggct
    30901 gactgcgcta cgcaaagacc atcctgacct attgatcatg gtcgatccgg tgattggcga
    30961 tattgatagc ggaatttatg tcaaacctga ccttcccgag gcgtatcgac aatatttact
    31021 gccgctggcg cagggaatta cccccaatat ctttgagctg gaaatcctga ccggtaaaaa
    31081 ttgccgcgat ctcgacagtg ccattgctgc cgcaaaaagt ctgctttcag acacattaaa
    31141 atgggtggtg attaccagcg cctccggtaa tgaagaaaat caggagatgc aggtggtggt
    31201 ggtcagtgcc gacagcgtga atgtcatttc ccattcacgg gtaaaaaccg acctgaaagg
    31261 gactggcgac ctgttttgtg ctcagcttat cagtggtttg ctgaaaggga aggcgttaaa
    31321 cgatgcggtg caccgtgcgg ggttgcgcgt actggaagtg atgcgctaca cccagcagca
    31381 tgagagcgat gaattgattt tgccgccgct ggcggaagca taaaaaatgg cgccgatggg
    31441 cgccattttt cactgcggca agaattactt cttgatgcgg ataaccgggg tttcacccac
    31501 ggttacgcta ccggacagtt tgatcagttc tttgatttcg tccatgttgg agataacaac
    31561 cggagtcagg gtagacttgg ctttctcttc cagtagcggc agatcaaatt caatgacagt
    31621 atcgccaact ttcacgcgct gaccttcttc agcaatacgc ttgaagcctt cgcctttcag
    31681 ttcaacggtg tcgataccga agtggacgaa cagttcaacg ccgctatcag attcgataga
    31741 gaacgcgtga ttggtttcaa agattttacc aatggtaccg tctacaggcg cgaccatttt
    31801 gttacccgtt ggtttgatag caataccatc accaacgatt ttttccgcaa aaacgacatc
    31861 cggcacgtct tcgatattga cgatctcgcc agagagcgga gcaatgatct caatagttcc
    31921 ggtatccttc ttgtcgtcgg aaaccagaga tttcagttta tcgaacaaac ccatgatctt
    31981 ctcctaagca gtaaattggg ccgcatctcg tggattagca gattgttttt tcttcaatga
    32041 acttgttaac cagcgtcatt aactcgtccg ttgtcggttg agcaagagcc tgctctgcta
    32101 acaccttcgc atcttcgaag ttcgtgttac ggataatctt cttaatgcgc gggatagaaa
    32161 tggcgctcat agagaattcg tccagaccca tccccagcaa cagaagtgta gcacgttcat
    32221 cgccagcaag ctcaccacac atgccagtcc atttgccttc agcatgagaa gcatcaataa
    32281 cttgcttgat caagttcagc acggacggtg acattggttg gtaaaggtgt gaaatcatat
    32341 cattaccacg gtcaactgcc agagtgtact gcgttaaatc attggtgccg atactaaaga
    32401 aatcaacttc tttggctaaa tgacgtgcaa ttgttgcggc agccggtgtt tccaccatta
    32461 cgccgatttc aattgactcg tcaaacgctt taccttcgtc gcgcagttcc tgtttgtaga
    32521 tttcgatctc tttgcgcagt gcacgcactt cttcaacaga gatgatcatc gggaacataa
    32581 tgcgcaattt accgaaagcc gaggcacgca ggatagcgcg gagctgatcg cgcaggatct
    32641 ctttacgatc catcgcgata cggatagcgc gccagccgag gaacgggttc tcttctttcg
    32701 ggaagttcat gtatggcagc tctttgtcgc cgccgatgtc catggtacga acgataaccg
    32761 cctgcgagcc acacgcttca gccactgctt tgtaagcagc aaactgttct tcttcagtgg
    32821 gcagcgcgtc gcggtccatg aacaggaact cagtacgata cagaccaacg ccttcagcgc
    32881 cgttacgctc tgcaccttca acgtcacgaa ccgtaccaat gttagcgcac acttctacct
    32941 ggtgaccgtc cagcgtaata gctggcagat ctttcagttt agcaagctct gctttttcag
    33001 aagccacttg ctcctgaaca gcgcgcattt tatcaataac ttcgttggtt ggattgacgt
    33061 aaacctgatt atttacggca tccagaatca gatagtcgtc atttttcacc tgagaggtga
    33121 cgctaccggt acccacgata gcaggcagtt ccagagaacg cgccatgata gaggtgtggg
    33181 aagtacggcc acccgcgtcg gtgatgaaac ccagcacctt cttcaggttc agctgtgcgg
    33241 tttcggacgg cgtcaggtca gcggcaacca gaatgacttc atcctgaatg gcgctcaggt
    33301 cgataatctt caggcccagg atgttgcgca gcaggcgctt accgatatca cgtacgtcag
    33361 ccgcacgttc tttcaggtat tcatcatcca gctcttccag ggcagaagcc tgaccttcga
    33421 taacttcatg agcagctgcg tcagctgtca tgtgcttatc tttaatcagg gctatgattt
    33481 cctgctccag ctcctcatct tcgagcagca taatatgccc ttcaaagatg gcttcttttt
    33541 cttcaccgaa cgtttcacca gctttcgttt tgatcgtttc cagctgggct gatgccttgg
    33601 cacgaccgct cagaaaacgt tcaacttcct gatcaacctg gtcggcagaa atttttttcc
    33661 ggtcaatgac aatttcgtct tctttcagaa gcagagcttt accgaaagcg atacccgggg
    33721 atgctaaaat gcctgaaatc ataaccctac cttacttgtg actgattttt aaaagaaccc
    33781 gggaaattac tcgagttccg ccatcagttt aaccagatgt tcaaccgctt tctgctcgtc
    33841 ttcgccttct gcggagatag tcacaacggt accttgagtc aggcccagag tctgcagttt
    33901 aaacaggctt ttcgcgctgg cgcttttgcc gttggaagtc acagtaattt cagaagtgaa
    33961 gcccttagct tcttttacaa actgggcagc agggcgggtg tgcagaccgt tcggagcggt
    34021 aatggtaact tcttgctgga acattgtatt tccccaactt ataggtttag tgttgtggaa
    34081 ctaaagtcta gcctggcggt tcgactttag cctgtattgt tagcgccagt ttttaacaga
    34141 cgcgacgcac gaagagcgca atacagtcca ttgctggcgg gtgttgaccg ctgacgtttc
    34201 gtacgtcatt aaacattatg ccgctaaagg aagaattgaa ccaaatcata aaatcgattc
    34261 agctttggct tttcctgtaa cgattaattt cgcgcatcaa aataattagt ctggttaaat
    34321 accagttccg acaggctgaa tcaatgccag gaggggcgaa agtttgaagc aggccacaaa
    34381 aaagcaccta aaaaggtgct tttttacgca tttttaacaa gctggcatta ctgttgcagt
    34441 tctttctcag tgaagagatc ggcaaacaat gcggtgctta aataacgctc acccgatgac
    34501 ggtagaataa ccacaatatt cttgttggta aagctttcat cttcttgtag tttcaacgcc
    34561 gcagcaacag ctgctccaga agagatacct gcaagaatac cttcttcttc catcagacga
    34621 cgcgcggtag aaatcgcttc ttcattggtg atgccaatga ctttatcgac cagcttgaga
    34681 tcgaggttag ctgggataaa accagcgcca ataccctgaa ttttatgcgg gccaggttta
    34741 atctcttcac cagccagtgc ctgggcgata actggagaat cggttggctc aacggcgaca
    34801 gagataagat cggtcttgcc tttggtgcct ttaatgtagc ggctgacgcc agtaagcgta
    34861 ccgccagtcc caacgccagc aataaataca tcaacctgac cgtcggtatc ttcccagatc
    34921 tccggaccgg tggttttttc gtgaatttca gggtttgccg gattgctgaa ttgttgcagc
    34981 agcaggtatt tctctggatt gctggcgaca atttcttctg ctttttggat tgcgcctttc
    35041 atgcctttag caccttccgt cagcaccagg tttgcaccta acgctttcag cagcttgcgg
    35101 cgttcaatac tcatggtttc tggcatggtc agggtgagtt tgtaaccgcg agcggcagct
    35161 acataggcca gtgcaatccc ggtattaccg ctggttggtt caaccagttc aacgcctggt
    35221 ttcagcacgc cgcgcttttc ggcatcccaa atcatgttgg caccgatacg gcacttaacg
    35281 ctgaagctgg ggttacgaga ttccaccttc gccagaatgc gtccgttacc gatgcgattc
    35341 aggcgaacca gcggcgtgtg accgatagtc agcgagttat cttcaaaaat cttactcatg
    35401 gcctgtcctt aactgtatga aattgggata caacaggtag catacccgct cagagaatat
    35461 gcggaagtaa ggatttagca tatctatata cagaagggaa ataatgacat gcaagatgga
    35521 ataaggggcg gcataagcca cccctgtttc acacaaacgg tttacaaaat aaccggtaga
    35581 ttgttaccgc cacatcgcgt gtttatcgcg atagcaatcg acccacatcg ccgtcgcgcc
    35641 acaaacggca acgggcatga tgaacagatt aagcagcggg atcatcgtaa acaggctggt
    35701 taaagcacca aactgcatat tggtgatttt gcgtgtgcgc agggcggtgc gcatctcttt
    35761 aaacggcact ttgtggttat cgaaggggta atcgcaatac tggatggcta acatccaggc
    35821 gctaaacagg aaccacagta ccggcgcgac ggtttgccca ataccaggga ttaagtaaag
    35881 aattagcaat acaattgcgc gcggcagata ccaggcaaat ttttgccatt cgcgtttcat
    35941 gattcgcggc acatctttca tgataccgaa aatcccggta tctggcggtg tagcgccagt
    36001 caatcgtgct tccagttgtt cagccaataa accgttaaac ggagcggcaa tccagttagc
    36061 aatcgtggag aagaaatagc caaacactaa cagcacagag atgacagcca gaggccacaa
    36121 cagataactc agccattgta gccagtccgg aacgtaactc atgagagtcg ggatccagac
    36181 atcgagctgt gtaaagagcc accagaatgc gccccccatc aacaaaatat tgaccagcag
    36241 cggtaaaata acgaaacgcc gaatcccagg ttgcgagacg agcttccagc cttgcgcaaa
    36301 atagtaaaaa ccgctgcgtg gggcagatgt gaatgatgaa accataatca ggatgagctc
    36361 cttttgacca atcccaggaa aattctgcgt attttaccgg gtaattgcgc aatggacagt
    36421 taggatatgt tcgaaaaaac agcaaaaagc acgatttcat ctatctttgt gctgtgaaag
    36481 ttaatagtgc acttgcactt gaggtaatcg gcaaatactc ttagtgagta aatgtttgcc
    36541 gtggtggcaa ggtgttagaa caacagagaa tataatgatg caggatttgc gtctgatatt
    36601 aatcattgtt ggcgcgatcg ccataatcgc tttactggta catggtttct ggaccagccg
    36661 taaagaacga tcttctatgt tccgcgatcg gccattaaaa cgaatgaagt caaaacgtga
    36721 cgacgattct tatgacgagg atgtcgaaga tgatgagggc gttggtgagg ttcgtgttca
    36781 ccgcgtgaat catgccccgg ctaacgctca ggagcatgag gctgctcgtc cgtcgccgca
    36841 acaccagtac caaccgcctt atgcgtctgc gcagccgcgt caaccggtcc agcagccgcc
    36901 tgaagcgcag gtaccgccgc aacatgctcc gcgtccagcg cagccggtgc agcagcctgc
    36961 ctatcagccg cagcctgaac agccgttgca gcagccagtt tcgccacagg tcgcgccagc
    37021 gccgcagcct gtgcattcag caccgcaacc ggcacaacag gctttccagc ctgcagaacc
    37081 cgtagcggca ccacagcctg agcctgtagc ggaaccggct ccagttatgg ataaaccgaa
    37141 gcgcaaagaa gcggtgatta tcatgaacgt cgcggcgcat cacggtagcg agctaaacgg
    37201 tgaactgctt cttaacagca ttcaacaagc gggcttcatt tttggcgata tgaatattta
    37261 ccatcgtcat cttagcccgg atggcagcgg cccggcgtta ttcagcctgg cgaatatggt
    37321 gaaaccggga acctttgatc ctgaaatgaa ggatttcact actccgggtg tcaccatctt
    37381 tatgcaggta ccgtcttacg gtgacgagct gcagaacttc aagctgatgc tgcaatctgc
    37441 gcagcatatt gccgatgaag tgggcggtgt cgtgcttgac gatcagcgcc gtatgatgac
    37501 tccgcagaaa ttgcgcgagt accaggacat catccgcgaa gtcaaagacg ccaacgcctg
    37561 atacacttaa ggcaaattaa ctcctcttcg aacccccgct tgtcgggggt ttttagcatt
    37621 gatggtgcga tatggaatca atcgaacaac aactgacaga actgcgaacg acgcttcgcc
    37681 atcatgaata tctttatcat gtgatggatg cgccggaaat tcccgacgct gaatacgaca
    37741 ggctgatgcg cgaactgcgc gagctggaaa ccaaacatcc agaactgatt acgcctgatt
    37801 cgcctaccca acgtgtaggc gctgcgccgc tggcggcttt cagccagata cgccatgaag
    37861 taccaatgct gtcactggat aacgtttttg atgaagaaag ctttcttgct ttcaacaaac
    37921 gtgtgcagga ccgtctgaaa aacaacgaga aagtcacctg gtgctgtgag ctgaagctgg
    37981 atggccttgc cgtcagtatt ctgtatgaaa atggcgtttt agtcagtgcc gcgacccgtg
    38041 gcgatggcac caccggggaa gatatcacgt ctaatgtgcg tactattcgc gctattccgc
    38101 tgaagctgca cggagagaat atcccggcgc gtctggaagt gcgtggtgaa gtgttcctgc
    38161 cgcaggcggg gttcgaaaag attaacgaag atgcgcgacg cacgggcggg aaagtttttg
    38221 ctaacccacg taatgcggca gctggttcac tgcgtcagct tgatccgcgt attacagcga
    38281 agcgaccgct cacttttttc tgctatggcg ttggtgttct ggaaggtggc gagctgccgg
    38341 atactcatct tggccgttta ctgcaattta aaaagtgggg gttgccggtc agcgatcggg
    38401 taacgctttg tgaatcggcg gaagaagtgc tggcgttcta tcacaaagtg gaagaagacc
    38461 gcccgacgct gggctttgat atcgacggcg tggtgattaa ggtcaactca ctggaacagc
    38521 aggagcagct tggctttgtc gcgcgtgccc cgcgctgggc ggtagcgttt aaattcccgg
    38581 cgcaggagca gatgaccttt gtgcgtgacg tcgagtttca ggttgggcgt actggcgcga
    38641 ttacgcctgt tgcgcgtctg gaacctgtcc atgttgctgg cgtgctggtg agtaacgcaa
    38701 ccttacacaa tgcggatgaa atcgaacgtc ttggtttacg cattggcgat aaagtggtga
    38761 ttcgccgcgc tggcgacgtg atcccgcagg tggttaacgt cgtgctttct gaacgcccgg
    38821 aagatacccg tgaggttgta ttcccgacgc attgtccggt atgtggttct gacgttgagc
    38881 gtgtggaagg tgaagcggtt gcccgctgta ccggtggcct gatttgcgga gcgcagcgta
    38941 aagagtcgct gaaacacttt gtttcccgcc gtgcgatgga tgttgacgga atgggcgaca
    39001 aaatcatcga tcagctggtt gaaaaagaat atgtccatac tccggcagat ctgttcaaac
    39061 tcaccgcagg caaactgacc ggactggagc gtatggggcc aaaatcggca caaaacgtgg
    39121 ttaacgcgct agaaaaagcg aaagaaacca cctttgctcg cttcctctat gcacttggca
    39181 tccgtgaagt cggcgaggcc accgcagcag gtctggcggc atatttcggc acgctggaag
    39241 cgctggaagc cgcttcgatt gaagagctgc aaaaggtgcc tgatgttggc attgtcgttg
    39301 catcccacgt tcacaacttc tttgccgaag aaagcaaccg caatgtcatc agcgagctgt
    39361 tggcggaagg tgttcactgg cctgcgccga tcgttatcaa cgcggaagag attgacagcc
    39421 cgtttgctgg taaaaccgtg gtgcttacgg gcagcttaag ccagatgtcg cgtgatgacg
    39481 ctaaagctcg actggttgaa ctgggcgcga aagtcgcggg cagcgtgtcg aagaaaaccg
    39541 atctggtgat tgccggagaa gcggcaggtt ctaaactggc gaaagcgcag gaactgggca
    39601 ttgaagtcat cgacgaagcg gaaatgctgc gtttgctggg tagctgagat ggaaaaagag
    39661 cagctgattg aaatagccaa tacgataatg ccgtttggca aatataaagg gcgtcgctta
    39721 atcgacctgc cggaggagta tctgctgtgg tttgcccgca aagatgaatt cccggcaggg
    39781 aagctcggtg agctaatgca aatcacgctg ctgattaaaa ccgaggggct gacgcaactg
    39841 gtccagcccc tgaagcgtcc gctttaagct ttatcggcgc tgctttcctg ctgtgcctgt
    39901 aactgttcgg tctggcgttt gtatcgacgc gccagcaccg cacagaccat caattggatc
    39961 tgatggaaaa tcatcagggg cagcaccatc ataccgatca ccgatgtggg gaacagaatg
    40021 tttgccatcg ggatgccatt tgccagactc tttttcgaac cacaaaagac gatagtaatt
    40081 tcatctgcct tattgaagcc cagtcggcgt gccataaaga cgttaactac aatcacgata
    40141 gccagaagaa cgcagctgac caccacgata aacagcaatg atccccagcc aactttatgc
    40201 cagataccat taacgacggc ttcgctgaac gctgtataaa ccaccaacag aatggacgtc
    40261 tggtcagttt tcgcaatcca ttttttattg cgcgacaccc agtcaccaat ccacggccgg
    40321 gaaagatgcc ccaacacaaa cggcagcagc agttgcagca taattttacc gacctgctca
    40381 aggctgcccc ctgcaccgtg aacattcatc accagaccaa ccagcaatgg tgaaaggaaa
    40441 atccccagca ggctggatgc tgacgcagaa caaaccgccg ccgcgacgtt accgcccgcc
    40501 attgacgtga aggcgattgc agactgcacg gtagccggga gaatgcacaa gtagagaaaa
    40561 ccggagtaga gcatcgggtc gacatttacc ggtttccacc aggcaaacag tacacccaga
    40621 atcggaaaca gcacgaaggt gctgcacatt acccacaaat gcagtcgcca gtgaccaccg
    40681 ccagcaataa tcgcctcacg cgacaacttc gcgccgtgca taaagaacag cagggcaata
    40741 gctgcggtgg tcagattttc aaagaagggg acgaaatcgc ctctggccgg aaagaaagag
    40801 gccagcaaca ccaccgtgat cagggttaag gtgaaaggat cgaggatacg aaaaagtttc
    40861 ataaagactc cagatgatcg atggttctat tgtgcttctt ccagtttgag aaataaaatt
    40921 gatttattgc atccattcat gaagaaaaca gatgaattat tctttaaaac aattaaaggt
    40981 tttcgtcaca gtagcgcagg agaaaagttt tagtcgtgca ggagagcgta tcggcctgag
    41041 ccagtcggca gtgagtcaca gtgtgaagga gctggaaaat catactggtg ttcgcctgct
    41101 ggacagaacc acgcgtgaag tggtgcttac agatgcaggg cagcagctgg ctttgcgtct
    41161 tgagcgactg ctggatgaac tgaacagcac gttgcgcgat accgggcgta tggggcaaca
    41221 actgagcgga aaagttcggg tcgctgccag ccagaccatt tccgcgcatc ttattccgca
    41281 atgcattgct gaaagccatc gccgctatcc agatattcag tttgtcctgc acgatcgtcc
    41341 gcagcagtgg gtaatggaaa gtattcgcca gggagatgtc gactttggca tcgtcatcga
    41401 tccaggccca gtgggcgatc tgcaatgtga agcgattctt tccgagcctt tctttctgct
    41461 ttgccatcgc gatagcgctt tggccgtgga agattatgta ccctggcagg cattgcagga
    41521 agcgaaattg gtgttgcagg attacgcgtc aggcagccga ccgctgattg acgcagcgct
    41581 ggcgcgcaat ggtattcagg cgaatattgt gcaggagatt ggacatccgg cgacgctgtt
    41641 cccgatggta gccgcaggca tcggcatcag tattcttccc gcactggcgc taccattgcc
    41701 tgaaggtagc ccactggtgg taaagcgcat tacgccggtt gttgaacgcc agttgatgct
    41761 ggtgcgcagg aagaaccgtt cactttccac cgccgctgaa gcgttatggg acgtggtacg
    41821 agaccagggc aatgcgctaa tggctggtcg ggaaggggat ccgttgtatc agatatagat
    41881 atcgatatga gtcgtttttt caacaggatt tagaagggat acattcagag acaaacactg
    41941 ctctttctcc tgcgcctttt ctgcctgctg tttctgcaac tgcgccagtt gtgtttccag
    42001 tagggtgatt tgctgttgaa tcaattcggc ctgtttttgc ttgtcttcag cactgccgct
    42061 agtgtctaca atctctttaa tttgttgagt gagtttgatg atttgctgac ttatccgcgc
    42121 gatttgtgaa gcaacatcgc taccttgtga tgccctgtta ctactctgtg tttgtatgga
    42181 aggaattgaa gttgaagaga tagtggccat tgttcagtcc tcgtcactgt acgaggtaat
    42241 atcggtagaa gaacaaggaa cttgagaaga aaaatcaatc ttacaaatcg cagatagcaa
    42301 aaaagcgcct ttagggcgct tttttacatt ggtgggtcgt gcaggattcg aacctgcgac
    42361 caattgatta aaagtcaact gctctaccaa ctgagctaac gacccgaagt ggtgggtgat
    42421 gacgggatcg aaccgccgac cccctccttg taagggaggt gctctcccag ctgagctaat
    42481 cacccactta ggtacttcac atttttacaa gaaatttagc tggcgagaaa gtggtgggtg
    42541 atgacgggat cgaaccgccg accccctcct tgtaagggag gtgctctccc agctgagcta
    42601 atcacccact tctcaatttc ttgctacacg gcggagacta cataaagtag ttggtgggtg
    42661 atgacgggat cgaaccgccg accccctcct tgtaagggag gtgctctccc agctgagcta
    42721 atcacccccg ctgtgtggag tcgcattata gggagagttc aaaatgagtc aacgcatttt
    42781 ctaaagaaat tgttcgttcg tcgtaaattt aagcaagatg atcgcaaaac agaccgtgtt
    42841 gcgcaatttg tcaacgaaaa caataatgcg taaggtagaa acccgaacta cattgaggaa
    42901 tcaggcggga gtgatagaat atcgcccact caatttttcc aggatttgcc ggttgtcggc
    42961 atctttctaa acgtaaggcc atttcatgaa aatcaaaact cgcttcgcgc caagcccaac
    43021 aggctatctg cacgttggcg gcgcgcgtac tgctctttac tcctggcttt ttgcacgtaa
    43081 ccacggcggt gagttcgtgc tgcgtattga agacaccgat cttgagcgtt ccacgccgga
    43141 agctatcgaa gccattatgg atggcatgaa ctggctgagc ctggagtggg atgaaggtcc
    43201 gtactaccag accaaacgtt ttgatcgcta caatgcggtg atcgatcaga tgctggaaga
    43261 gggcactgct tataaatgct attgctctaa agagcgcctg gaagcgctgc gcgaagagca
    43321 aatggcgaaa ggtgagaagc cgcgttatga cggtcgctgc cgccacagcc atgagcatca
    43381 tgctgatgat gaaccgtgtg tcgtgcgttt tgctaatccg caggaaggtt ctgttgtttt
    43441 tgacgatcag atccgtggtc cgatcgagtt cagcaaccag gagctggatg atctgattat
    43501 ccgccgtacc gatggttccc caacctataa cttctgtgtg gttgtcgatg actgggatat
    43561 ggaaatcacc cacgttatcc gtggcgaaga ccatatcaac aacacgccgc gccagatcaa
    43621 cattcttaag gccctgaaag cgccggtgcc ggtttacgcg cacgtttcta tgatcaatgg
    43681 cgatgacggt aaaaaactgt ccaaacgtca cggggcagtc agcgtaatgc agtatcgtga
    43741 tgacggttat ttgccagaag cactgctgaa ctatctggtg cgtctgggct ggtcccacgg
    43801 cgatcaggaa atcttcactc gtgaagagat gatcaaatac ttcactttga atgccgtcag
    43861 caaatctgcc agtgcgttca acaccgacaa gctgctgtgg ctgaaccatc actacattaa
    43921 cgcgctgccg ccggagtatg ttgctactca cttacagtgg cacattgagc aggaaaatat
    43981 cgatacccgt aacggcccgc agctggctga tctggtgaaa ctgctgggcg aacgctgcaa
    44041 gacgctgaaa gagatggcac agagctgccg ttatttctac gaagattttg ctgagttcga
    44101 tgccgatgcg gcgaaaaaac atctgcgtcc ggtagcgcgt cagccgctgg aagtggttcg
    44161 tgacaaactg gccgcgatta ctgactggac cgctgaaaac gttcatcacg ctattcaggc
    44221 gacggcggat gagctggaag tgggtatggg taaagttggt atgccgctgc gtgtcgccgt
    44281 aaccggtgcg gggcagtctc cagcactgga tgttaccgtt cacgcaattg gtaagacccg
    44341 cagtatcgag cgtatcaaca aagcgctgga ttttattgct gaacgcgaaa atcagcagta
    44401 attagcgtgt aaaaagataa acggcaggag ataatatcct gccgtttttt atttatgctg
    44461 attcgtcaat atcgagacgg gcgaggaaat tgcgaattcc ttcacgtgac aaaaattgcg
    44521 cgactttttc ctgctcaatg tctgtcatat tatctatcgc gttgatgatt tgtcgatacg
    44581 ccggggcgcg tgctccagga gcgtattcag caattctctc ttcagcttcc atcaacattg
    44641 gtgtgttatg gaaggctggc gtgttctgaa taaactcgca aacttgcgta tcgaccagaa
    44701 taagtctggc acgaccgcct ttcacgccgg gaaatttttc cgttttccag cctttttctc
    44761 tgatccaacg gttaacagtt tgtttagcca caccgaggca ttcagccagt tcttcggtgg
    44821 tcattttgtt gcgtaatctt ttcatattat ttgctatcgc gaatccctaa gcgttgtaac
    44881 aatccgataa tcccttcccg cagaagcaag gatgtaaact gtttttgttc aactggcgtc
    44941 atctctttcg ccagtgtcac cagcaatact tcaagcggcg catcaccaga aagggcaggc
    45001 gcttctccct gaccttctgg acgttcagca ttgcgaatat attcacgaac ctgttcattg
    45061 acgtgaacca gtcgggcttt gccaccctgg acgccaggtt ttggtgacgt tgtccagcct
    45121 tccttgcgta cccatttatt aatggtctgg cggctatagc cggtcagtct ggcaagttca
    45181 tctggtgtca tcctctcctt gaacataaca attccctgaa tgtatgtggg tctattagta
    45241 gttcatttta taacaccact ttacaggaaa ccgtgacatg aataactact gaatgcgagc
    45301 ggttttccaa aattgttcat ttgcctgatt tttcagcgat tgaaactaca cgttgcaatt
    45361 tgccgttgac acattcgggc ggaattcata tgatgccgcc cgtcaactcg acaagcttta
    45421 cgtgacgggg ctatagctca gctgggagag cgcttgcatg gcatgcaaga ggtcagcggt
    45481 tcgatcccgc ttagctccac caaattttgc acccagcaaa cttggtacgt aaacgcatcg
    45541 tggggctata gctcagctgg gagagcgctt gcatggcatg caagaggtca gcggttcgat
    45601 cccgcttagc tccaccaaat ttccaaccct cgctgcaaag cgggggtttt ttgtctctgc
    45661 tttttgccgc ttttgtaata cagtctacgt ccgggttagt gccgcctggt gaaagcatca
    45721 ttggatgaaa aatcggcaac aggctggccc cctgtttgct tcgcgatgcg aataaactta
    45781 ttatttgtgt gcctgaaaac cccgatcagt gagagtagtg tactcatgtt tgtggagcat
    45841 aacctgataa aaaatatcaa gatattcaca ctagcgttta cgctcaccgt ggtacttatt
    45901 cagctatccc gttttatttc gccacttgcc attatccatt ccagttatat ctttctggcg
    45961 tggatgccac tgtgcgtaat gctgtcaatc ttgtttatct ttggctggcg cggtgtcgtt
    46021 cccgttttat gcgggatgtt ttgcaccaat ctgtggaact ttcatctctc ttttttacag
    46081 actgcggtca tgctcggtag ccagacgttt gtcgtgttgt gtgcctgcgc aatattacgc
    46141 tggcagctgg ggacgcgttg gcgttatgga ttgaccagcc gatatgtctg gcaacgtctg
    46201 ttctggcttg gtttggtgac gccgatcggc atcaaatgca gcatgtatct tgtggggagc
    46261 ttctttgatt tcccgctaaa gatatccacc tttttcggcg atgcggatgc cattttcacg
    46321 gtcgttgatt tgctaagcct tttcaccgct gtgctgattt acaacatgct tttctactat
    46381 ctcactcgca tgattgtaag tccccacttt gcgcagatat tgtggcgcag ggatatcgct
    46441 ccgtcgttgg gcaaagagaa acgcgcattt accttaagct ggctggcagc gttaagcgtg
    46501 ctgctacttc tgttgtgcac accttatgaa aacgacttta ttgccggtta cctggtaccc
    46561 gttttcttca tcatctttac cctcggggtc ggtaagcttc gctatccgtt tttaaatctc
    46621 acctgggctg tttcaacgct ttgccttctg aattacaacc agaacttttt gcaaggggtg
    46681 gaaaccgaat attcgctggc atttattctt gcggtgctga tttcctttag cgtttgcctg
    46741 ctctatatgg tgcgcattta tcatcgcagt gaatggctta atcgccgctg gcatttgcag
    46801 gcgctgacag atccgttaac gctcctaccc aactttcgtg cgttggaaca agcgccggag
    46861 caagaggcgg gcaagagttt ttgctgcctg cgcattgata atcttgagtt tatgagtcgt
    46921 cattacggct taatgatgcg cgttcactgt atccgctcaa tttgccgtac gctgctgccg
    46981 ttgatgcagg aaaacgaaaa gttgtatcaa ttgccgggta gtgaactgct gttagtgctg
    47041 agcgggccgg aaacggaagg gcgactccag catatggtta acatcctgaa tagtcggcaa
    47101 attcactgga acaataccgg gctggatatg ggctatggtg ctgcctgggg gcgttttgat
    47161 ggaaatcagg aaaccctgca acccttgttg gggcagttaa gctggctggc ggagcaatcc
    47221 tgcgcacatc atcatgtgct ggcgctggat agcagagagg agatggtttc cgggcagacc
    47281 actaaacagg tgctattgct gaataccatt cgcacggcgt tagatcaggg tgatttgctg
    47341 ctctacgccc agccaattcg caacaaagag ggtgaaggtt atgatgagat cctcgcgcga
    47401 ctgaaatatg acggcggcat tatgaccccg gataagtttc tgccccttat tgctcagttt
    47461 aaccttagcg cgcgttttga tttgcaagtg ctggaatcct tgttgaagtg gctggcaaca
    47521 cacccttgcg acaaaaaagg accgcgcttt tcagtcaatt taatgccgct cacgctgctg
    47581 caaaagaata ttgccgggcg gattattcgt ctgtttaagc gttatcacat ctccccgcag
    47641 gcggtcattc ttgagatcac cgaggagcag gcgttttcta acgcagaaag cagcatgtac
    47701 aacatcgagc agctgcataa gtttggtttc cggattgcga ttgatgactt tggcaccgga
    47761 tatgccaact acgaacggtt aaagcgtttg caggctgata tcatcaaaat tgatggcgtc
    47821 tttgtgaaag atattgtcac gaacacgctg gatgcgatga ttgtgagatc aattaccgat
    47881 ctggcgaaag cgaagtcatt gagtgtggtc gcggagtttg tcgagacgca acagcagcag
    47941 gcgctattgc ataagctcgg ggtgcaatat ctgcaagggt atttgattgg tcgcccgcag
    48001 ccattagctg attaacaggc gtaaaaaaac cggggaatta tccccggctt ttttatgtat
    48061 ggtcttacag caccagtgct gcgattgacg cagacagcac actcaccagg gtagagccgt
    48121 aaaccagctt cagaccgaag cgagaaacca cgttaccttg ctcttcattc aggcctttaa
    48181 ctgcacctgc gataatcccg attgaagaga agttagcgaa ggaaaccagg aacacagaga
    48241 tgatgccttc agcacgcgga gagagcgtgg aagcaatttt ctgcagatcc atcatcgcaa
    48301 cgaactcgtt ggaaaccagt ttggtcgcca tgatactgcc cacttgcagt gcttcactgg
    48361 aaggaacacc catcacccat gcaatcggat agaagatgta gcccaggatg ccctggaagg
    48421 agatgctgta gccaaaccag ccagtaacgg tggcaaacag tgcgttcagc gcggcgatca
    48481 gggcgataaa gccaatcagc atcgcggcaa cgataatggc aactttgaaa cctgccagaa
    48541 tgtattcacc cagcatttcg aagaagctct gaccttcgtg caggttggac atctggatgt
    48601 tttcttcact ggcatcaaca cggtaaggat tgatcagcga cagcacgata aaggtgctga
    48661 acatgttcag taccagcgca gcaacgacgt atttcggttc cagcatggtc atgtatgcac
    48721 caacgatgga catcgacacg gtggacattg ccgtggcagc catggtgtac atacgattac
    48781 gggagatttt gccgaggata tctttatagg caataaagtt ttcagactga cccagaatca
    48841 gggagctgac ggcgttaaag gattccagtt tgcccatgcc gttgactttg gagagcagga
    48901 aaccaattgc gcggatgatc accggcaaca cgcgaatgtg ctggagaata ccgatcagtg
    48961 cagagataaa gacgattggg cacagcactt tcaggaagaa gaatgccagg ccttgatcat
    49021 tcatgctacc aaagacgaag ttagtccctt cgttggcaaa tccgagcagt ttttcgaaca
    49081 tttcggagaa gcctttcacg aagcctaaac caacgtcgga gttcaggaag aaccacgcca
    49141 gtaacacttc gataacaagc agttgaataa cataacggat acgaattttt ttgcggtcgc
    49201 tgcttaccag cagtgcgaga atcgcaacaa cggcaagtgc cagtacaaaa tgaaggacgc
    49261 ggtccatatt tgctccaaat atgaggcagg ttaaatttcc gtgcacattc tatgtaacat
    49321 ggttaaggaa aacgagatct gacacacact ataatgacgt cctgtgacag gcttcaaaaa
    49381 tagtgatctg tcatacattt ctgctatgtt gtgtatggaa gctgaaagtt atgtaaatgt
    49441 gctaacatta aacataacca taacattcaa gtcatcaatc ttttcgtagt cataatcctg
    49501 gtctatcaga gaaatcacca caatccattt aaatgaattt gataataatt ctcgtttggc
    49561 atagcatgaa acatagcaaa ggctatgttt tagaggcaca agatgacgaa ctatcgcgtt
    49621 gagagtagca gcggacgggc ggcgcgcaag atgaggctcg cattaatggg acctgcgttc
    49681 attgcggcga ttggttatat cgatcccggt aactttgcga ccaatattca ggcgggtgct
    49741 agcttcggct atcagctact gtgggttgtc gtttgggcca acctgatggc gatgctgatt
    49801 cagatcctct ctgccaaact agggattgcc accggtaaaa atctggcgga gcagattcgc
    49861 gatcactatc cgcgtcccgt agtgtggttc tattgggttc aggcagaaat tattgcgatg
    49921 gcaaccgacc tggcggaatt tattggtgcg gcgatcggtt ttaaactcat tcttggtgtt
    49981 tcgttgttgc agggcgcggt gctgacgggg atcgcgactt tcctgatttt aatgctgcaa
    50041 cgtcgcggac aaaaaccgct ggagaaagtg attggcgggt tactgttgtt tgttgccgcg
    50101 gcttacattg tcgagttgat tttctcccag cctaacctgg cgcagctggg taaaggaatg
    50161 gtgatcccga gtttacctac ttcggaagcg gtcttcctgg cagcaggcgt gttaggggcg
    50221 acgattatgc cgcatgtgat ttatttgcac tcctcgctca ctcagcattt acatggcggt
    50281 tcgcgtcaac aacgttattc cgccaccaaa tgggatgtgg ctatcgccat gactattgcc
    50341 ggttttgtca atctggcgat gatggctaca gctgcggcgg cgttccactt ttccggtcat
    50401 actggtgttg ccgatcttga tgaggcttat ctgacgctgc aaccgctgtt aagccacgct
    50461 gcggcaacgg tctttggatt aagcctggtt gctgcggggc tgtcttcaac ggtggtgggg
    50521 acactggcgg ggcaggtggt gatgcagggc ttcattcgct ttcatatccc gctgtgggtg
    50581 cgtcgtacag tcaccatgtt gccgtcattt attgtcattc tgatgggatt agatccgaca
    50641 cggattctgg ttatgagtca ggtactgtta agttttggta tcgctctggc gctggttcca
    50701 ctgctgattt tcaccagtga cagcaagttg atgggcgatc tggtgaacag caaacgcgta
    50761 aaacagacag gctgggtgat tgtggtgctg gtcgtggcgc tgaatatctg gttgttggtg
    50821 gggacggcgc tgggattgta gttgaatgag cgtcgcatct ggcactattg gcggatgcgg
    50881 cgtaaacgcc ttatccgccc tacgcgttaa agagccggtt tgtaggcctg ataagacgca
    50941 ctagcgtcgc atcaggcatt gtgctccatt ggcggacgcg tttaatggcg gtgcccatga
    51001 ccccggcctt ttccgcgatg atcgtcacga tcgcgccagc cttcacgata gccacgctca
    51061 tacgctttac gcttatccca gccacggtgg tagccattat catgacgcca ccaacggttt
    51121 ttgcgccact cataattgcg atgccagtag tcacggtcgc gccagtgacc accgtcccag
    51181 taattaccgt aatgatcgcg atcgccaatt tgtaatttga ttgatggcag tagggtgatt
    51241 tcacctgcgt ttgctgcaag cggggtaaat gccatcaggg cggccgccag aaacagtgac
    51301 ctgaacattg ttattctcct tcacgctcga agccgtcagc ggcctgttaa cgcaatatta
    51361 cggggaggta aagccccgta tcatcgccat aactcttaaa tcataaagga gagcattttt
    51421 tgctaaacgt tatcgtgggg tggctgttgc ttcggacgat tgaccatcat catcggctta
    51481 cctgctaata acagccatgc cggaagcatg acgatacaga gcagcggtag caatgtggta
    51541 ttgggtacaa cgactgccgc cataaaaaga cttaaccagc catcgcgtgt taccaccagc
    51601 acgatgccga gaatagcgca agaaacggtt attgccgctg gtacggcggg aacgtgctca
    51661 tgcagcatca accctaatgc cacgccgaca aacactgccg ggaagattcg cccaccgcga
    51721 aagccactgg cggcagcaac gaccagggcg gcaagtttaa ttaccgccag caaaaagtaa
    51781 tcgctggtgc tgaaagcctg atttgccacc atctgctgca tctcatccag ccctttaaac
    51841 agcgaaactg gtccaccaat aacccccaga ataccgagaa taaatccgcc aatacccagc
    51901 acgagcaccg gatttttcat ttgatgcatc atcgcgtgca accgtggtaa gcaccatacg
    51961 gcgaccatcc ctgctgcgat ggcaatcgcc gcgacaattg caccgctgag aatatcggtc
    52021 atttccatct gtccgtaatg agcaatgggc agtgaaaaat gaggatggaa aaataatccg
    52081 gtagtaagtg caccagctgc tgccgccatt aacggcgcaa agagacgatc ccatagcgga
    52141 acttcactac tgccatttaa ggtttgcgaa aatatcaacg ccgccgcaac aggagtgcca
    52201 aacagtgcgc cgatggttcc ggcagaggct aaaatagtcc actccattcg gttgacgcgc
    52261 ggtaacagac gagcgccaat ggcaaccgca agggcgatat tgacggtcat gatcggatgt
    52321 tccggcccca ggctgacgcc gccagcaaga ccgagaatta atgctacgat aagtccaggt
    52381 agcgcagagg gcggaaccgg tgcgccgatc agcggttcac aggcggggtc tggtccggca
    52441 tgaccctggc tgaaacggat aaccaacccc accgcaatac ccgttagcgt taatacaccg
    52501 atgatccaga ggggtgaatc ctgggctatc cccagagttc ccggcagtcg ttgccagagc
    52561 aaattctgta ataccgaggc gattttcatc accacaatca gaataagact ggacgcaatc
    52621 ccaattgcca cggcggggag cgataataac aacatggttc tggctcgcgg atggagcatg
    52681 ttctattcct tatgcggggt cagatactta gtttgcccag cttgcaaaaa ggcatcgctg
    52741 caattggtgc tgaaacgata aagtaattgt gtgacccaga tcgatattta cagggagcct
    52801 gcctttccgg cgttgttgtt atgcccccag gtatttacag tgtgagaaag aattattttg
    52861 actttagcgg agcagttgaa gaatgacaaa gtatgcatta gtcggtgatg tgggcggcac
    52921 caacgcacgt cttgctctgt gtgatattgc cagtggtgaa atctcgcagg ctaagaccta
    52981 ttcagggctt gattacccca gcctcgaagc ggtcattcgc gtttatcttg aagaacataa
    53041 ggtcgaggtg aaagacggct gtattgccat cgcttgccca attaccggtg actgggtggc
    53101 gatgaccaac catacctggg cgttctcaat tgccgaaatg aaaaagaatc tcggttttag
    53161 ccatctggaa attattaacg attttaccgc tgtatcgatg gcgatcccga tgctgaaaaa
    53221 agagcatctg attcagtttg gtggcgcaga accggtcgaa ggtaagccta ttgcggttta
    53281 cggtgccgga acggggcttg gggttgcgca tctggtccat gtcgataagc gttgggtaag
    53341 cttgccaggc gaaggcggtc acgttgattt tgcgccgaat agtgaagaag aggccattat
    53401 cctcgaaata ttgcgtgcgg aaattggtca tgtttcggcg gagcgcgtgc tttctggccc
    53461 tgggctggtg aatttgtatc gcgcaattgt gaaagctgac aaccgcctgc cagaaaatct
    53521 caagccaaaa gatattaccg aacgcgcgct ggctgacagc tgcaccgatt gccgccgcgc
    53581 attgtcgctg ttttgcgtca ttatgggccg ttttggcggc aatctggcgc tcaatctcgg
    53641 gacatttggc ggcgtgttta ttgcgggcgg tatcgtgccg cgcttccttg agttcttcaa
    53701 agcctccggt ttccgtgccg catttgaaga taaagggcgc tttaaagaat atgtccatga
    53761 tattccggtg tatctcatcg tccatgacaa tccgggcctt ctcggttccg gtgcacattt
    53821 acgccagacc ttaggtcaca ttctgtaaat ccttcctttt atatcgggag gtaactctcc
    53881 cgataatctt ttaaatcata cagtttattc aatttttctt tgtgtcccct cacaaggtcg
    53941 acctgcgtca cacttccgta cagcgggatt aattctccag taaatgcatt atttgtctgg
    54001 taacggcgat ttgttttgca cgttcataat ttcactcgtc aactatcact gaacgaggaa
    54061 ttaacgatga gtaagaaact gattgcctta tgtgcctgcc cgatgggcct ggctcacacc
    54121 tttatggccg ctcaggcgct ggaagaagcg gcggtagaag ccggttatga agtgaaaatt
    54181 gaaacccagg gcgcggacgg tatccagaat cgcctgacgg cgcaggatat cgccgaagcg
    54241 accatcatca tccactccgt ggcagttacc ccggaagata acgaacgttt cgaatcacgc
    54301 gacgtttatg aaatcacttt gcaggacgca attaaaaacg ctgcgggcat catcaaagaa
    54361 atcgaagaga tgattgcctc tgaacaacag taatattcga cagggataat tgttatggcc
    54421 attaaaaaac gcagtgcaac cgttgtgcct ggcgcatccg gtgcggcagc ggcagttaag
    54481 aatccgcagg cctctaaaac cagcttctgg ggtgaactcc cgcagcatgt gatgtcaggg
    54541 atttcacgca tggtgccgac cttaattatg ggcggtgtga tcctcgcttt cagccagctg
    54601 attgcttata gctggcttaa aattcctgct gagatcggca tcatggatgc tcttaatagc
    54661 gggaaattct ccggtttcga cctctcctta cttaaatttg cctggctgtc gcagtccttc
    54721 ggcggcgtgt tgtttggttt tgccattccg atgtttgctg cttttgtggc gaactctatc
    54781 ggtggcaaac tggcgttccc ggctggtttt atcggcgggt tgatgtctac ccagccgacg
    54841 caactgctga acttcgatcc cagcactatg caatgggcga cctcttcgcc ggtgccgtcc
    54901 accttcattg gtgcgctgat tatttctatc gttgccggtt accttgtgaa gtggatgaac
    54961 cagaaaatcc agttaccgga tttcctgtta gcgttcaaaa ccacattttt gctcccgatt
    55021 ctttccgcca tttttgtcat gctggcgatg tactacgtca tcaccccctt tggtggctgg
    55081 atcaacggcg gtatccgtac tgtgctgact gccgcaggtg agaagggcgc gctgatgtac
    55141 gcaatgggga tcgccgcggc gacagcaatc gaccttggtg gcccgatcaa caaagccgca
    55201 ggttttgttg ccttcagctt taccactgac cacgtattac cggtcaccgc tcgttctatc
    55261 gctatcgtta ttccgccgat tggtctgggg ctggcgacca ttatcgaccg tcgtttaacc
    55321 ggcaaacgcc tgttcaacgc tcaactttat ccgcagggta agaccgccat gttcctggcg
    55381 tttatgggga tcagtgaggg tgcgattccg tttgcgctgg aaagccccat caccgccatt
    55441 ccgtcgtata tggtcggcgc tattgtcggc tcaaccgccg ctgtctggct gggcgcagtg
    55501 caatggttcc cggagtccgc tatctgggca tggccgctgg tcactaacct gggcgtctat
    55561 atggcaggga tcgcgctggg ggcagtcata actgcgctga tggtggtgtt cctgcgtctg
    55621 atgatgttcc gtaaaggcaa attgttaatc gatagcctgt aagaaggaaa atccagatga
    55681 cattactcgc ttcgctgcgc gactggctta aggcgcaaca actggatgca gtgcttctct
    55741 cctcacggca gaacaaacag ccgcatctgg ggatctccac cggatcaggt tatgtggtga
    55801 ttagccgtga aagtgcgcac attctggtgg attcgcgcta ttacgttgag gtggaagccc
    55861 gtgcgcaagg ctaccagctg catttgcttg acgcgacgaa cacgcttacc actatcgtca
    55921 atcaaatcat tgccgatgaa cagttgcaaa cgctcggttt tgagggccag caggtgagtt
    55981 gggaaaccgc gcaccgctgg cagtctgaac tcaatgcgaa actggttagc gccacgccgg
    56041 atgtgctgcg gcaaatcaaa acgccagagg aggtggagaa aatccgcctc gcctgtggga
    56101 ttgctgatcg cggtgcagag catattcgcc gctttattca ggcggggatg agcgagcgcg
    56161 agatagccgc tgaactggag tggtttatgc gccagcaggg cgcagaaaaa gcctcttttg
    56221 acaccattgt cgccagtggc tggcgtgggg cgctgccgca cggcaaagcc agcgacaaga
    56281 ttgttgcagc gggcgagttt gtcactctcg atttcggtgc gctgtatcag ggctactgct
    56341 ctgatatgac gcgcaccttg ctggtgaatg gcgaaggggt gagcgccgaa tctcacccgc
    56401 tgtttaacgt ctatcaaatt gtcctgcagg cacagctcgc agcaatctcc gcgattcgcc
    56461 ccggcgtgcg ctgccagcag gttgacgatg ccgcgcgccg ggtcattaca gaagcaggtt
    56521 atggcgacta tttcggtcat aacaccggtc acgctatcgg cattgaagtt catgaagatc
    56581 cgcgtttttc accgcgggac accacgacgc tacagccagg catgttactg accgtggagc
    56641 cggggattta tttgccaggg caagggggcg tgcgcatcga agatgttgtg ctggttaccc
    56701 cgcaaggcgc agaagtgctc tacgccatgc cgaaaacagt gttgctcacg ggagaggcat
    56761 aatggattta tcgctattaa aagcgttgag cgaggcagat gcgatcgcct cctcggaaca
    56821 ggaagtgcgg cagatcctgc tggaagaagc ggatcgcctg caaaaagaag tgcgatttga
    56881 tggtctggga tcggtgctga tccgcctgaa tgaatcgaca ggtccgaagg tgatgatctg
    56941 tgcgcatatg gacgaagtgg gatttatggt gcgcagcatc tcccgcgaag gggcgattga
    57001 tgtgctgccg gttggcaacg tacgcatggc tgcccgccag ctgcagccgg tgcgcatcac
    57061 cacccgtgaa gagtgcaaaa ttccaggcct gcttgacggc gaccggcagg ggaatgacgt
    57121 cagcgccatg cgcgtggaca ttggtgcgcg ctcctatgac gaagtgatgc aggcgggaat
    57181 tcgtcccggc gatcgcgtca cgtttgatac cacttttcag gttctccctc accagcgagt
    57241 gatggggaaa gcctttgatg accgcctcgg ttgctatctg ctggtgacgt tactgcgcga
    57301 actgcacgac gccgaactac ctgcggaagt gtggctggtg gcaagttcca gcgaagaggt
    57361 gggattacgc ggcgggcaaa ctgccacccg cgcggtgtcg ccggacgtcg ccattgtgct
    57421 tgataccgcc tgctgggcga aaaactttga ttatggcgcg gctaaccatc gccagattgg
    57481 taacgggccg atgctggtgt taagcgacaa gtcgctgatt gcgccgccaa aacttaccgc
    57541 ctgggtcgaa accgtggcgg cagaaattgg cgtgccgttg caggcagata tgttcagcaa
    57601 cggcggcacg gacggcgggg cggtgcactt aaccggcacc ggcgtgccca cagtggtgat
    57661 ggggccagca acccgccatg gacattgcgc cgcatcgatt gccgattgcc gcgacatttt
    57721 gcagatgcag caacttttat ctgcccttat tcaacgtctt acgcgtgaga cggttgttca
    57781 actgacggat ttcagatgat ctcctgatta acccggagcg gttatgttaa cgattcaatt
    57841 tctctgtcct ttgcctaacg gtctacatgc tcgtccggcg tgggaactta aagaacagtg
    57901 cagccagtgg caaagcgaaa tcacttttat taaccatcgc cagaacgcaa aggcagatgc
    57961 gaaaagctcg ctggcgctga ttggcaccgg caccctattt aatgacagtt gcagcctgaa
    58021 cattagcggc agcgatgaag agcaggcgcg gcgcgtgctg gaagagtaca tccaggtgcg
    58081 ctttatcgac agcgacagcg ttcagcctac gcaggcagaa ctgacggcgc atccgctgcc
    58141 gcgttcatta agccgcctta acccggattt actgtacggc aatgtgctgg caagcggcgt
    58201 cggcgtgggt acgctgaccc tgttacaaag cgacagcctc gacagttatc gggcaatccc
    58261 cgccagtgcg caagattcca cccggctgga gcacagcctg gcaacgcttg ccgagcaact
    58321 gaaccagcaa ttgcgtgagc gtgacggcga aagcaaaact atcctcagcg cccatttgtc
    58381 gctgattcag gatgatgaat ttgcaggcaa tatccgtcgc ctgatgacag aacagcatca
    58441 ggggctgggg gcggcgatca tcagcaatat ggagcaggtt tgcgccaaac tttctgcctc
    58501 tgccagcgat tatctgcgcg aacgtgttag cgacattcgc gatatcagcg aacagttgct
    58561 gcatatcacc tggccggaac tgaagccgcg caacaagctg gtgcttgaaa aaccgaccat
    58621 tctggtggct gaagatttaa ccccaagcca gtttttgagc cttgatttga aaaatcttgc
    58681 gggcatgatt ctggagaaaa ccgggcgcac ctcgcataca ctgattctgg cccgtgcctc
    58741 ggcgatcccg gtactgagtg gcttgccgct ggatgcgatt gcccgttatg ccgggcaacc
    58801 tgcagtgctt gacgcccagt gcggcgtgct ggcgattaac ccgaatgacg cggtgagcgg
    58861 ttattatcag gtcgcgcaga cgctggcgga taaacgccaa aaacaacagg cgcaggctgc
    58921 cgcgcagctg gcctattccc gtgataacaa gcgtattgat attgcggcga atatcggcac
    58981 cgctctggaa gcgccaggcg cgtttgccaa cggcgcggaa ggtgtcgggc tgttccgtac
    59041 cgaaatgctc tatatggatc gcgacagcgc gccggacgag caggagcaat ttgaagccta
    59101 ccagcaggtg ctactggcgg cgggcgacaa gccgattatc ttccgcacga tggacatcgg
    59161 cggcgataaa agcattcctt atctgaatat tccccaggaa gagaacccgt tcctcggcta
    59221 tcgcgcggta cgtatttacc cggaatttgc tggcctgttc cgcactcaac tgcgggccat
    59281 tttgcgcgcc gccagtttcg gcaacgccca gttgatgatc ccgatggttc acagcctcga
    59341 tcagatctta tgggtgaaag gcgagatcca aaaagcgatc gttgagctta agcgcgatgg
    59401 cctgcgtcat gcagagacga ttactctggg tatcatggtg gaagtgccgt cggtgtgtta
    59461 catcatcgac cacttctgcg atgaggtcga tttcttcagt atcggttcta acgatatgac
    59521 ccagtatctg tatgcggtcg atcgtaataa cccgcgcgta tcgccgctgt ataacccgat
    59581 tacgccatcg ttcctgcgca tgttgcagca gattgttacc actgcgcatc agcggggcaa
    59641 atgggtaggc atttgcggtg aactgggcgg tgaaagccgt tatctgccgc tactgcttgg
    59701 gctgggcctg gatgagctga gtatgagtag cccgcgtatt ccggcggtga aaagccagct
    59761 tcgtcaactg gatagcgagg cgtgtcggga actggcgcgt caggcatgtg aatgccgcag
    59821 tgcgcaggaa attgaagcgt tactcaccgc ctttacgccg gaagaagacg ttcgcccact
    59881 gctggcgctg gagaatatct ttgttgatca ggattttagc aataaagagc aggcgatcca
    59941 gttcctgtgc ggcaacctcg gcgttaacgg gcgcactgaa catccgtttg agctggaaga
    60001 agacgtctgg cagcgggaag agattgttac caccggcgtt ggttttggcg tagcgatccc
    60061 gcacaccaaa tctcagtgga tccgtcattc cagtatcagc attgcccggc tggcgaaacc
    60121 gattgactgg cagtcagaaa tgggcgaagt cgaactggtg atcatgctga cgctgggtgc
    60181 taacgaaggg atgaatcatg tgaaagtctt ctcgcagctg gcgcgtaaac tggtgaataa
    60241 aaacttccgc cagtcgttgt ttgccgcgca agatgcacaa agtatcctga cgctgctgga
    60301 aacagaatta accttctgac gttagccctg aaaacgggcg ctgtactctc ccggcgtcag
    60361 accaaactga cgccggaaaa cgcgacaaaa atagtcgcta tccggaaaac cgcaacgctg
    60421 tgccacttca tgaattgaca gatgatattt ctgcaaaatc atcctcgcct tcgccattcg
    60481 cacccaacgc acatactcga taaaacgcat cgttccatgc tgagcaaaca gttttgacag
    60541 atgattgggc gtgatattaa aaaactgcgc cacgctctcg cgggtgagcg gctgggcata
    60601 attatcctga acccagttac aaatgctgtg atagagaaaa tcgccgcgcg gctgcgaatt
    60661 gcccggcggc atattcacca cgttacggca aagatgcagc aaacttaaca ccagtggctg
    60721 aatgatattc tgctccagcg gcgaacggct aagatgggtg agggcggtaa gcatcgcttc
    60781 accttcaccg cgttgcaggc tgggaagctg gatctggcga gcaggatgca acaacgacgt
    60841 ggtgcggcta tcgtaaaacg ataacccaag ccaggtcggt gcgaacacca ggcttaacag
    60901 catcaccggt ttgttgttga tcggtaaatt agccgcgcgt gccggaataa acagcatttc
    60961 tccttccacc attcgctgct gctttgcttc cagcaggttg ccgtattcgc cgcgcagcac
    61021 gatatccaga cggggaaaat caatacataa actgcccacc ggtaacgagg caggctggct
    61081 ggcaaaccag acgcgcccca gtagttgcgg gttaagcacc aggccgctga acagatcggc
    61141 gaaaaattgt tgatcggcgg gcaagcctgg tgctttcatg aaagttcccg attaaagatg
    61201 cattaactgg cgaaattctt tcactttgct gcggctgacc ggcacttcaa aatccagatc
    61261 tttcagtcgc agaatgtagg tgttattaaa ccacggttcg atttcgcgta ttttgttcag
    61321 attgacacaa aatgagcgat ggcagcggaa aaaatgcgac ggcggcagtt tgctgcaaaa
    61381 ttcggtaatg ttcatcggca ttacgtagga ttcacgccgc gtatagacaa aggtcatttt
    61441 ctcgtgcgct tcggcgtaat agatatcgtt aattggcgtg acgattattc gctcatcttt
    61501 caccagatta atggtgtcat tctcacgcgt taccgtcgcg gcaggcgtac tgctggtctg
    61561 ctgttgttgc caggccgctt ccagtttttg cagcatcccg gtaatacgtg actcctgata
    61621 cggtttgaga atgtagtcaa acgcctccag ttcaaacgct tctaccgcat gttctttcca
    61681 cgcggtgatg aacacaataa acggtttatg ggcgaactgg ctgatgtttt gcgccagcaa
    61741 cacgccatcc agcgacggaa tattgatatc cagaaaaatg gcgtcgacgc ggttatgctg
    61801 caaaaacttc aacacgtcca gaccgtcgtc aaaggtgccg acaatctcca tctggctgtg
    61861 ctctttaatt agccagctca gttcctgttg tgccaggaat tcgtcttcaa caatgatgac
    61921 tttcacaata tcactccggc tcaaagcaat aacgtagcct gtgaggcgac tggggtgcgt
    61981 tggttaggaa tgtaaaacgc aatttccgtc cccggctcca ggcggcggat atgcagcccc
    62041 tcgccataca ataacttcac gcgatgatgg acattcagca ggccaatttt attgcccggc
    62101 atttcattcg cttcgacccg ctcaatcacc tttggatcga tgccgtgccc ggtatctcgc
    62161 accgcaatgc gtacccgatt tccgcactct gcaacgctga tggtgacaac gcctttacct
    62221 ttgcaaggct gaataccgtg gacaatggcg ttctccacca acggctggat cagcaggctg
    62281 ggaatgcagc aattcacctc ttcatcaata tcatagataa ccgtcagctt gtcaccaaag
    62341 cgggcctgct caatggcaat atagtcttta atttgataca gctctttttt gatatcgatt
    62401 tgctcatcgt cttttaattc aatgttatag cgcagataac gcgacagatt aaagatcaac
    62461 tggcgagcgg tatccggatt cagacggatt gacgatgaaa tagcgttcag agcgttaaac
    62521 agaaaatggg gattaatttt gctttgcagg gcgcgaagct ctgccttatt tgccatttca
    62581 cgtagctgct cggcgcgtga aacctccagt tgcgtggaga tgatttgcga cagaccgacc
    62641 gccatttcct gtaatgacga ggtgatctga tgcgcgtggc agtagtaaat tttcagcgtt
    62701 ccggtcacga cccctttctc ccacaatggg atcaccagca tggaatgaat ctctggtgtg
    62761 cggtgggctt catcattgtt tttaatgatg atttttccgt aattcatcgc ctgacgggta
    62821 gtcgggctaa tgaagtcatc gccattctga tagttatgtt cacccacgcc aacataggcc
    62881 agcacatgat cggtattagt aatcgccacc gcatcggcgt gaatgtcatc gcggataatt
    62941 tcgcagacct tgcgtaatga ctcgctattg acatggcgaa acagcggtag cgttttgttg
    63001 gcgatatcca gcgccagctt ggcctgccgc gcggcgctgg cctctttttc gccctcaacg
    63061 ctttgcacca gaagcacaat aaagccgata cagacgctac cgaggatcat tggaatgccg
    63121 attttagaga cgatatcgat ccccaacgcg gtagttggtg cccagacaat taccagaatc
    63181 atggtcaacg tctcacacaa catgccgccg agaataccga cgcgccagcg ctgtgctttg
    63241 gggattttca ggtttatcca gcctgatata caacccgcca gaatgctggt gataaagcag
    63301 gggatcgccg tcacgccgcc gatatcaatt aaataccggt gaatacccgc aatcacgccg
    63361 gtaatgatgc ctacccacgg gccaaacaga atcccgccgg acatcaccgc gataatacgt
    63421 acgttcacca gcgagccttc tacgggaacg ccggaccagg tgctgaacag ggcgaacagc
    63481 gagaaaatgg cggtaacggc gagcaattct tttggggagt gcgccgactt gtgcaacagt
    63541 tcgcgaaaca ggcggatacg gatgagaaag aacaggcaga taagcattaa cgctgcccga
    63601 tcgaagaccg ccagcagcat gttgaatatt tcgtgcacgg gtgactctga ataaggatta
    63661 aacctctatg ataggtaacc tgaaggctga tgaccagcag gccgtttttg aggaaaaacc
    63721 ataaatttaa aaggggattg aaagataaat ggtgtattag caatgtatct cttgataatg
    63781 cacttctggc tggtaaattt attgaaatta taatgttaat aaaattggtg gtaattttct
    63841 tgttagcgta gaaaaatttc ctgtttttga agtggagttc ctcatttaaa gccattgata
    63901 aaaatgttct aaaacgctgg acagacagaa attaatcagg ctattttcaa aacagccacc
    63961 attgtggcag cgtcgctcgg acggtccggg cgctaacgtt aatctgagga aattatggct
    64021 gacactcgcc ctgaacgtcg ctttacgcgc attgatcgtc tcccgcccta cgtttttaac
    64081 atcaccgctg aactgaaaat ggctgcgcgt cggcgcggcg aagatattat cgatttcagc
    64141 atgggtaacc cggacggtgc gactccgccg catatcgtcg aaaaattatg tactgtggcc
    64201 cagcgcccgg acacgcatgg ttactccact tcacgcggca ttccgcggtt acgtcgcgcc
    64261 atttcccact ggtatcagga tcgctacgac gttgaaatcg acccggaatc agaagccatc
    64321 gtcactattg gttcgaaaga gggcctggcg catctgatgc tggcgacgct ggatcatggt
    64381 gacacggtgc tggtgccgaa tccaagttac ccgatccata tttatggcgc ggtgattgcc
    64441 ggggcgcagg tacgctcagt gccgctggtg gaaggtgtcg atttcttcaa cgaactggag
    64501 cgagccattc gtgaaagtta tccgaaaccg aagatgatga tcctcggctt cccgtcaaac
    64561 ccaaccgcgc aatgcgtgga actggagttc ttcgaaaaag tagtggcgct ggcgaaacgc
    64621 tacgatgtgc tggtggtcca tgacctggcc tatgccgata tcgtctacga tggctggaaa
    64681 gcgccgtcaa ttatgcaggt accgggtgca cgcgatgtgg cagtcgagtt ctttacgctg
    64741 tcgaaaagct acaacatggc gggctggcgt atcggcttta tggttggcaa caaaacgctg
    64801 gtcagcgccc tggctcgtat taaaagctat cacgattacg gcacctttac gccgttgcag
    64861 gtggcggcga ttgcggcgct ggagggcgat caacagtgcg tgcgcgacat tgccgaacag
    64921 tacaaacgcc gccgtgatgt attggttaaa gggttgcatg aagcgggctg gatggttgaa
    64981 atgccgaagg cttcgatgta tgtctgggcg aaaatcccgg aaccatatgc ggccatggga
    65041 tcgctggaat ttgccaagaa gctccttaac gaagcgaagg tttgtgtctc gccggggatt
    65101 ggctttggcg actatggtga tacgcatgtt cgctttgcac tgattgaaaa ccgcgaccgt
    65161 attcgtcagg ccatcagagg gattaaagcg atgttccgtg ccgacggttt actacccgcc
    65221 agcagcaaac atattcacga aaacgcggaa taaacaccgt cgtcagaaat gcaaacagga
    65281 gcctgatggc tcctgttttt cattgcacag tttgctttta gatcatcagg gcaaaagtac
    65341 tggcccaaac gatgaccata aaagaaatgc ccataaagaa atatttcact ttacatctct
    65401 ccgcgtaatt actgttacgc ctgaatgact tcattacacc tgatacagtg agttgacacc
    65461 gggcaaagcg accttaaaag ccctgtattt taccgtgggc atcaccccag aattctgagc
    65521 taaactgctc gagacggcgc taatgtacgc ctaaaactga aacgagacaa gaggcatttt
    65581 cttatttact tttagtaact tacaagtgtc tcatatcggc gacagtttaa tttctgacgg
    65641 taataattag atattcagcg aaggaaaaaa ccttaagaaa aaagccataa aaaccatgag
    65701 gttattatgg ccgatttgag gagggaaaga gtaagagcag tttgttaaat gtacaacgac
    65761 gattctccca ccgggcgcgt tttaaagcga cggtggatcc agaggtactg ctccggtgcg
    65821 cgcatgatct ctttctcgat aatcttgttc atataggcag cggcttgatt ttcatctgtc
    65881 gggtagcctt ccatctctgg ggtgatgaac aaacgatatc cgctgtaatc cgcttttctt
    65941 accatcgtta cggtcaacat ggctgcgcca gagagacggg agagaacata ggtgccattg
    66001 gttgtggcga cattttccac cgcaaagaac ggcgcgaagg agctgccttt acgaccataa
    66061 tcctgatcgg gagcaaacca taccgcttca cctttcttca gtgcaccgac aatgccgcgc
    66121 agattatttc tgccgatcat cgctttgtta gagcgcatgc gcccacgggt ctgcacccat
    66181 tccatcagct gattattatg tggacgatag gtagccatca ttggttggca cagtcccatc
    66241 acgcggccgc ccagttccag cgacataaaa tggacgccga caaccattac gccgcgattt
    66301 tgcatttgtg cgcgtttaag gttatccaac ccttcaacat caaaccattt acgtacgcga
    66361 ctgtcgggcc agaaccatgc catgccggtt tctaccagcg ccatgccgag tgaacgaaag
    66421 ttttcggcaa tcatcttctc gcgttcttcc gcagaatgct gcgggaaaca aagttccagg
    66481 tttttacggg cgatagattc acgacgtttc aggaatggtc gcgccattgc gccaatacgc
    66541 gtgccgagaa agcagagaac aggataagga agctgtaccc aaagccagag tacaccaagc
    66601 ccaaaccatg tgagccagta gcgaggatgt agaaactcgc gggaaaattt gcattgtgga
    66661 aacatagtta ccttctgtag atacgaattg ttgtatcgca gaagattcca tgtcgacagc
    66721 ggtacactca attggttggg ccatcatgta cgacaatggt tcctgtaaag agtgtaaaga
    66781 ctagtcagga cataaccacg aggagcatga atgcggtatc tgtactttat cactcgctga
    66841 ctgctttcag ctactgatta ttaatcgtgc aaagtaaata tttttccgta cacaacagtc
    66901 ttgcatttaa catgctgttt tcattgatgc ttagcaaaaa ttgccagagg ttaaggattg
    66961 tcttactatt aaagtgactg aagttacagg ttttttagcg cggcaggagg ttgagctatg
    67021 atttatttat ggatgtttct cgccctgtgt attgtctgcg taagcggcta catcggtcag
    67081 gtactgaacg tggtatcggc ggtctcttct ttcttcggca tggtgatcct cgctgcactc
    67141 atttattact tcaccatgtg gttaactggc ggtaatgaac tagtgacggg gatatttatg
    67201 tttcttgccc cggcttgtgg cttgatgatt cgctttatgg tggggtatgg caggcgatag
    67261 tgggtcagga tggctcattt gggcaggtgt tcacatcagc atcagacatg attgttcacc
    67321 tgccatgtga cagacgctat cgcacaggat gaataagata attcgccttt gtcggataag
    67381 taggcgtgat ttcttctgtg aggtttaatg gtggcgcatc ttctctcatc ttaaacaaaa
    67441 tcgcctgtga tggctgaagt tttgtagagt gtgtggttgt catcgctgat gttttttcag
    67501 tctctttata gctcctctca cttacaccac cagaaatgga aaatgcaaaa acattgcatg
    67561 ccataataga gac
//
LOCUS       DAPOAV010000012        67331 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.012, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000012 DAPOAV010000000
VERSION     DAPOAV010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 67331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67331
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.012"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..1071
                     /locus_tag="RN951_000951"
     CDS             <1..1071
                     /locus_tag="RN951_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
                     /protein_id="HDX2525993.1"
                     /translation="EHKLSDILLLTICAVISGAEGWEDIEDFGETHLDFLKQYGDFEN
                     GIPVHDTIARVVSCISPSKFHECFINWMRDCHTSDDKDVIAIDGKTLRHSYDKSRRKG
                     AIHVISAFSTMHSLVIGQIRTDEKSNEITAIPELLNMLDIKGKIITTDAMGCQKDIAE
                     KIQKQGGDYLFAVKGNQGRLNKAFEEKFPLKELNNPEHDSYAISEKSHGREEIRLHIV
                     CDVPDELIDFTFEWKGLKKLCVAVSFRSIIAEQKKEPEMTVRYYISSADLTAEKFATA
                     IRNHWHVENKLHRRLDVVMNEDDYKIRRGNAAELFSGIRHIAINILTNEKVFKAGLRR
                     KMRKAAMDRNYLASVLAGSGLS"
     gene            complement(1112..1882)
                     /gene="yafV"
                     /locus_tag="RN951_000952"
     CDS             complement(1112..1882)
                     /gene="yafV"
                     /locus_tag="RN951_000952"
                     /EC_number="3.5.1.111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutaramate amidase"
                     /protein_id="HDX2525994.1"
                     /translation="MPGLKITLLQQPLVWMDGPANLRHFDRQLEGITGRDVIVLPEMF
                     TSGFAMEAAASSLAQDDVVNWMTAKAQQCNALIAGSVALQTESGSVNRFLLVEPGGTV
                     HFYDKRHLFRMADEHLHYKAGNARVIVEWRGWRILPLVCYDLRFPVWSRNLNDYDLAL
                     YVANWPAPRSLHWQALLTARAIENQAYVAGCNRVGSDGNGCHYRGDSRVINPQGEIIA
                     TADAHQATRIDAELSMAALREYREKFPAWQDADEFRLW"
     gene            2063..2509
                     /gene="ivy"
                     /locus_tag="RN951_000953"
     CDS             2063..2509
                     /gene="ivy"
                     /locus_tag="RN951_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308274.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ivy family C-type lysozyme inhibitor"
                     /protein_id="HDX2525995.1"
                     /translation="MFKAITTVAALVIATSAMAQDDLTISSLAKGETTKAAFNQMVQG
                     HKLPAWVMKGGTYTPAQTVTLGDETYQVMSACKPHDCGSQRIAVMWSEKSNQMTGLFS
                     TIDEKTSQEKLTWLNVNDALSIDGKTVLFAALTGSLENHPDGFNFK"
     gene            complement(2552..4996)
                     /gene="fadE"
                     /locus_tag="RN951_000954"
     CDS             complement(2552..4996)
                     /gene="fadE"
                     /locus_tag="RN951_000954"
                     /EC_number="1.3.8.7"
                     /EC_number="1.3.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414756.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase FadE"
                     /protein_id="HDX2525996.1"
                     /translation="MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWS
                     AWVLVPLAIILVPFNFAPMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDL
                     FQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLK
                     EHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGT
                     DEQKDHYLPRLARGQEIPCFALTSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWN
                     KRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTPGVEIGRRHFPLNVP
                     FQNGPTRGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALA
                     TGAYAHIRRQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAI
                     VKYHCTHRGQQSIIDAMDITGGKGIMLGQSNFLARAYQGAPIAITVEGANILTRSMMI
                     FGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLFKHIGHVGSNKVRSFWLGLTRGLTSST
                     PTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISARLGDILSQLYLASAV
                     LKRYDDEGRNEADLPLVHWGVQDALYQAEQAMDDLLQNFPNRVVAGLLNVVIFPTGRH
                     YLAPSDKLDHKVAKILQVPNATRSRIGRGQYLTPSEHNPVGLLEEALVDVIAADPIHQ
                     RICKELGKNLPFTRLDELAHNALVKGLIDKDEAAILVKAEESRLRSINVDDFDPEELA
                     TKPVKLPEKVRKVEAA"
     gene            5236..5814
                     /gene="lpcA"
                     /locus_tag="RN951_000955"
     CDS             5236..5814
                     /gene="lpcA"
                     /locus_tag="RN951_000955"
                     /EC_number="5.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-sedoheptulose 7-phosphate isomerase"
                     /protein_id="HDX2525997.1"
                     /translation="MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAG
                     GKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFS
                     RYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEI
                     RVPHFGYADRIQEIHIKVIHILIQLIEKEMVK"
     gene            6020..6787
                     /locus_tag="RN951_000956"
     CDS             6020..6787
                     /locus_tag="RN951_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II glutamine amidotransferase"
                     /protein_id="HDX2525998.1"
                     /translation="MCELLGMSANVPTDICFSFTGLVQRGGGTGPHKDGWGITFYEGK
                     GCRTFKDPQPSFNSPIAKLVQDYPIKSCSVVAHIRQANRGEVALENTHPFTRELWGRN
                     WTYAHNGQLTGYKSLETGNFRPVGETDSEKAFCWLLHKLTQRYPRTPGNMAAVFKYIA
                     SLADELRQKGVFNMLLSDGRYVMAYCSTNLHWITRRAPFGVATLLDQDVEIDFSSQTT
                     PNDVVTVIATQPLTGNETWQKIMPGEWRLFCLGERVV"
     gene            complement(6758..7498)
                     /locus_tag="RN951_000957"
     CDS             complement(6758..7498)
                     /locus_tag="RN951_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein L,D-transpeptidase"
                     /protein_id="HDX2525999.1"
                     /translation="MRKIALILAMLLIPCVSFAGLLGSSSSTTPVSKEYKQQLMGSPV
                     YIQIFKEERTLDLYVKMGEQYQLLDSYKICKYSGGLGPKQRQGDFKSPEGFYSVQRNQ
                     LKPDSRYYKAINIGFPNAYDRAHGYEGKYLMIHGDCVSIGCYAMTNQGIDEIFQFVTG
                     ALVFGQPSVQVSIYPFRMTDANMKRHKYSNFKDFWEQLKPGYDYFEQTRKPPTVSVVN
                     GRYVVSKPLSHEVVQPQLASNYTLPEAK"
     gene            complement(7654..7932)
                     /gene="yafQ"
                     /locus_tag="RN951_000958"
     CDS             complement(7654..7932)
                     /gene="yafQ"
                     /locus_tag="RN951_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YafQ"
                     /protein_id="HDX2526000.1"
                     /translation="MIQRDIEYSGQYSKDVKLAQKRHKDMNKLKYLMTLLINNTLPLP
                     AVYKDHPLQGSWKGYRDAHVEPDWILIYKLTDKLLRFERTGTHAALFG"
     gene            complement(7935..8195)
                     /gene="dinJ"
                     /locus_tag="RN951_000959"
     CDS             complement(7935..8195)
                     /gene="dinJ"
                     /locus_tag="RN951_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin DinJ"
                     /protein_id="HDX2526001.1"
                     /translation="MAANAFVRARIDEDLKNQAADVLAGMGLTISDLVRITLTKVARE
                     KALPFDLREPNQLTIQSIKNSEAGIDVHKAKDADDLFDKLGI"
     gene            8405..9154
                     /locus_tag="RN951_000960"
     CDS             8405..9154
                     /locus_tag="RN951_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDX2526002.1"
                     /translation="MSLPSIPSFVLSGLLLICLPFSSFASATTSHISFSYAARQRMQN
                     RARLLKQYQTHLKKQASYIVEGNAESKRALRQHNREQIKQHPEWFPAPLKASDRRWQA
                     LAENNHFLSSDHLHNITEVAIHRLEQQLGKPYVWGGTRPDKGFDCSGLVFYAYNKILE
                     AKLPRTANEMYHYRRATIVANNDLRRGDLLFFHIHSREIADHMGVYLGDGQFIESPRT
                     GETIRISRLAEPFWQDHFLGARRILTEETIL"
     gene            9330..9827
                     /gene="rayT"
                     /locus_tag="RN951_000961"
     CDS             9330..9827
                     /gene="rayT"
                     /locus_tag="RN951_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="REP-associated tyrosine transposase RayT"
                     /protein_id="HDX2526003.1"
                     /translation="MSEYRRYYIKGGTWFFTVNLRNRRSQLLTTQYQMLRHAIIKVKR
                     DRPFEINAWVVLPEHMHCIWTLPEGDDDFSSRWREIKKQFTHACGLKNIWQPRFWEHA
                     IRNTKDYRHHVDYIYINPVKHGWVKQVSDWPFSTFHRDVARGLYPIDWAGDVTDFSAG
                     ERIIS"
     gene            complement(10051..11763)
                     /locus_tag="RN951_000962"
                     /pseudo
     CDS             complement(10051..11763)
                     /locus_tag="RN951_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140833.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
     gene            11735..12520
                     /gene="lafU"
                     /locus_tag="RN951_000963"
     CDS             11735..12520
                     /gene="lafU"
                     /locus_tag="RN951_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706230.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative lateral flagellar export/assembly
                     protein LafU"
                     /protein_id="HDX2526004.1"
                     /translation="MTTIKLIVNSVSKSERESIIAALHGQSIFNGGGLSPLNKISPSH
                     PPKPATVAVPEETEKKARDVNEKTALLKKKSATELGELATSINTIARDAHMEANLEME
                     IVPQGLRVLIKDDQNRNMFERGSAKIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMA
                     YKNNIYNNWNLSGDRALSARRVLEEAGMPEDKVMQVSAMADQMLLDSKNPQSAGNRRI
                     EIMVLTKSASDTLYQYFGQHGDKVVQPLVQKLDKQQVLSQRTR"
     gene            12591..13646
                     /gene="dinB"
                     /locus_tag="RN951_000964"
     CDS             12591..13646
                     /gene="dinB"
                     /locus_tag="RN951_000964"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDX2526005.1"
                     /translation="MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTA
                     NYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSL
                     DEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNG
                     QFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVMLLKRFGKF
                     GRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAK
                     VKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTWDERRGGRGVRLVGL
                     HVTLLDPQMERQLVLGL"
     gene            13698..13991
                     /gene="yafN"
                     /locus_tag="RN951_000965"
     CDS             13698..13991
                     /gene="yafN"
                     /locus_tag="RN951_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system antitoxin YafN"
                     /protein_id="HDX2526006.1"
                     /translation="MHRILAEKSVNITELRKNPAKYFIDQPVAVLSNNRPAGYLLSAS
                     AFEALMDMLAEQEEKKPIKARFRPSAARLEEITRRAEQYLNDMTDDDFNDFKE"
     gene            13994..14392
                     /gene="yafO"
                     /locus_tag="RN951_000966"
     CDS             13994..14392
                     /gene="yafO"
                     /locus_tag="RN951_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YafO"
                     /protein_id="HDX2526007.1"
                     /translation="MRVFKTKLIRLQLTAEELDALTADFISYKRDGVLPDIFGRDALY
                     DDSFTWPLIKFERVAHIHLANENNPFPPQLRQFSRTNDEAHLVYCQGAFDEQAWLLIA
                     ILKPEPHKLARDNNQMHKIGKMAEAFRMRF"
     gene            14402..14854
                     /locus_tag="RN951_000967"
     CDS             14402..14854
                     /locus_tag="RN951_000967"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDX2526008.1"
                     /translation="MNNIQIRNYQPGDFQQLCAIFIRAVTMTASQHYSPQQISAWAQI
                     DESRWKEKLAKSQVWVAIINAQPVGFISRIEHYIDMLFVDPEYTRRGVASALLKPLIK
                     SESELTVDASITAKPFFERYGFQTVKQQRVECRGAWFTNFYMRYKPQH"
     gene            15172..15378
                     /locus_tag="RN951_000968"
                     /pseudo
     CDS             15172..15378
                     /locus_tag="RN951_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706235.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RtcB family protein"
     gene            15374..15895
                     /locus_tag="RN951_000969"
                     /pseudo
     CDS             15374..15895
                     /locus_tag="RN951_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602105.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor H"
     gene            complement(15952..17409)
                     /gene="pepD"
                     /locus_tag="RN951_000970"
     CDS             complement(15952..17409)
                     /gene="pepD"
                     /locus_tag="RN951_000970"
                     /EC_number="3.4.13.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosol nonspecific dipeptidase"
                     /protein_id="HDX2526009.1"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKG
                     FHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQGNWL
                     QADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGG
                     EIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDVL
                     KSLVNTYQEILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATPNGVIRN
                     SDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEA
                     KGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIG
                     PTITGPHSPDEQVHIESVGHYWTLLTELLKEIPAK"
     gene            17670..18128
                     /gene="gpt"
                     /locus_tag="RN951_000971"
     CDS             17670..18128
                     /gene="gpt"
                     /locus_tag="RN951_000971"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDX2526010.1"
                     /translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR"
     gene            18220..19464
                     /gene="frsA"
                     /locus_tag="RN951_000972"
     CDS             18220..19464
                     /gene="frsA"
                     /locus_tag="RN951_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase FrsA"
                     /protein_id="HDX2526011.1"
                     /translation="MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTI
                     PHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     TQAMVWQQKACAEDDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
                     AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYF
                     APRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFN
                     PVYRNFDKGLQEITDWIEKRLC"
     gene            19522..19923
                     /gene="crl"
                     /locus_tag="RN951_000973"
     CDS             19522..19923
                     /gene="crl"
                     /locus_tag="RN951_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-binding protein Crl"
                     /protein_id="HDX2526012.1"
                     /translation="MTLPSGHPKSRLIKKFTALGPYIREGKCEDNRFFFDCLAVCVNV
                     KPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWKSVPVKDTEVVERLEHTLRE
                     FHEKLRELLTTLNLKLEPADDFRDEPVKLTA"
     gene            complement(19962..21017)
                     /gene="phoE"
                     /locus_tag="RN951_000974"
     CDS             complement(19962..21017)
                     /gene="phoE"
                     /locus_tag="RN951_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoporin PhoE"
                     /protein_id="HDX2526013.1"
                     /translation="MKKSTLALVVMGIVASASVQAAEIYNKDGNKLDVYGKVKAMHYM
                     SDNASKDGDQSYIRFGFKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGL
                     KYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFF
                     GVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFSISGAYTNSDRTNEQN
                     LQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPITGGFANKTQNFEAVAQYQF
                     DFGLRPSLGYVLSKGKDIEGIGDEDLVNYIDVGATYYFNKNMSAFVDYKINQLDSDNK
                     LNINNDDIVAVGMTYQF"
     gene            21305..22408
                     /gene="proB"
                     /locus_tag="RN951_000975"
     CDS             21305..22408
                     /gene="proB"
                     /locus_tag="RN951_000975"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HDX2526014.1"
                     /translation="MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHR
                     IVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQML
                     LTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILA
                     GADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKL
                     QAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAG
                     EITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDA
                     LRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR"
     gene            22420..23673
                     /gene="proA"
                     /locus_tag="RN951_000976"
     CDS             22420..23673
                     /gene="proA"
                     /locus_tag="RN951_000976"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HDX2526015.1"
                     /translation="MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILN
                     ANAQDVADARANGLSEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSG
                     LRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQ
                     DALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVI
                     TGGIGVCHIYVDESVEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQ
                     MAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIR
                     EHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLH
                     ARGPMGLEALTTYKWIGIGDYTIRA"
     gene            23788..23863
                     /locus_tag="RN951_000977"
     tRNA            23788..23863
                     /locus_tag="RN951_000977"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:23821..23823,aa:Thr,seq:cgt)
     gene            complement(23878..25041)
                     /locus_tag="RN951_000978"
     CDS             complement(23878..25041)
                     /locus_tag="RN951_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDX2526016.1"
                     /translation="MSLFRRGEIWYASFTLPNGKRFKQSLGTKDKRQATELHDKLKAE
                     AWRVSKLGEIPDITFEEACVRWLEEKAHKKSLDDDKSRIGFWLQHFAGMQLRDITESK
                     IYSAMQKMTNRRHEENWKLRAEACRKKGKPVPEYTPKPASVATKATHLSFIKALLRAA
                     EREWKMLDKAPIIKVPQPKNKRIRWLEPHEAQRLIDECPEPLKSVVEFALATGLRRSN
                     IINLEWQQIDMQRRVAWINPEESKSNRAIGVALNDTACRVLKKQIGNHHRWVFVYKES
                     CTKPDGTKAPTVRKMRYDANTAWKAALRRAGIDDFRFHDLRHTWASWLVQVGVPLSVL
                     QEMGGWESIEMVRRYAHLAPNHLTEHARQIDSILNPSVPNLSQSKNKEGTNDV"
     gene            complement(25268..25573)
                     /locus_tag="RN951_000979"
     CDS             complement(25268..25573)
                     /locus_tag="RN951_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526017.1"
                     /translation="MTTFTDKELIKEIKERISSLDVRDDIERRAYEIALLSLEVEPDE
                     REAYELFMEKRFGDLVDRRRAKNGNNEYMAWDMTLGWIVWQQRAGIHFSTMSQQEVK"
     gene            complement(25573..25935)
                     /locus_tag="RN951_000980"
     CDS             complement(25573..25935)
                     /locus_tag="RN951_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526018.1"
                     /translation="MRMNVFEMEGFLRGRCVPRDLKVNETDAEYLVRKFDALEAKCAA
                     QENKVIPVSTELPPANESVLLFDANGEGWLIGWRSLWYTWGQKETGEWQWTFQVGDLE
                     NVNITHWAVMPKAPEAGA"
     gene            complement(25926..26462)
                     /gene="yfdR"
                     /locus_tag="RN951_000981"
     CDS             complement(25926..26462)
                     /gene="yfdR"
                     /locus_tag="RN951_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416862.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-deoxynucleotidase"
                     /protein_id="HDX2526019.1"
                     /translation="MSFIKTFSGKHFYYDRINKDDIDINDIAVSLSNICRFAGHLSHF
                     YSVAQHAVLCSQLVPQEFAFEALMHDATEAYCQDIPAPLKRLLPDYKQMEEKIDAVIR
                     EKYGLPPVMSTPVKYADLIMLATERRDLGLDDGSFWPVLEGIPATEMFNVIPLAPGHA
                     YGMFMERFNELSELRKCA"
     gene            complement(26590..27414)
                     /locus_tag="RN951_000982"
     CDS             complement(26590..27414)
                     /locus_tag="RN951_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2303 family protein"
                     /protein_id="HDX2526020.1"
                     /translation="MSQNLDATAINQIHALISAQGVNEIISKIGADAVALPENFRIHD
                     LEKFNLNRFRFRGTLSTASIDDFTRYSKDLADEGTRCFIDADNMRAVSVLNLGTIDEP
                     GHADNTATLKLKKTAPFSALLSVNGERNSQKSLAEWIEDWADYLVGFDANGDAIQATK
                     AAAAVRKITIEANQTADFEDNDFSGKRSLMESVEAKTKDIMPVAFEFKCVPFEGLKER
                     PFKLRLSIITGDRPVLVLRIIQLEAVQEEMANEFRDLLVEKFKDSKVETFIGTFTA"
     gene            complement(27480..27842)
                     /locus_tag="RN951_000983"
     CDS             complement(27480..27842)
                     /locus_tag="RN951_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416860.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526021.1"
                     /translation="MASERSTDVQAFIGELDGGVFETKIGAVLSEVASGVMNTKTKGK
                     VSLNLEIEPFDENRVKIKHKLSYVRPTNRGKISEEDTTETPMYVNRGGRLTILQEDQG
                     QLLTLAGEPDGKLRAAGR"
     gene            complement(27857..28168)
                     /locus_tag="RN951_000984"
                     /pseudo
     CDS             complement(27857..28168)
                     /locus_tag="RN951_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            28313..28828
                     /locus_tag="RN951_000985"
     CDS             28313..28828
                     /locus_tag="RN951_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309531.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526022.1"
                     /translation="MIAELTAAMTAIREIAQIAKLMNEAKTQAEVNAAIGELNSKLAS
                     IQRECVSLVELLGSYQEINASLKAKIAEFENFEAQTEGYILNQLESGTFVYSKEVIVN
                     GDSITMHLCPKCFGQKIVSILQPFPVSEDELFHKSRCLHCENKFLMNKNPDYVSPPSI
                     EELARKLNGNL"
     gene            complement(29056..29682)
                     /locus_tag="RN951_000986"
     CDS             complement(29056..29682)
                     /locus_tag="RN951_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HDX2526023.1"
                     /translation="METVGQRIKALRRVTGTSQKELGKFCGVSDVAVGYWEKDINTPG
                     GEALSKLAKFFNTSIDYILYGAEFEGKLVTNMRRVPVISWVQAGQFTECRAAEVFSEV
                     DKWVDTSLKIGDNSFALEVKGDSMTNPNGLPTIPEGATVIVDPDAEPRHGKIVIARLD
                     GTNEATVKKLVIDGPQKFLVPLNPRYPNIPINGNCLIIGVVKGVQYEL"
     gene            29780..29980
                     /locus_tag="RN951_000987"
     CDS             29780..29980
                     /locus_tag="RN951_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HDX2526024.1"
                     /translation="MTTDDIESYFGSIEKVAAFFGITTEAVYQWRNRPGQLIPKGRAA
                     EAAYRTCGRLPFKPELYEKSNG"
     gene            30018..30569
                     /locus_tag="RN951_000988"
     CDS             30018..30569
                     /locus_tag="RN951_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415665.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526025.1"
                     /translation="MGKHHWKVEKQPEWYVKAVRKTIAALPGGYAEAADWLDVTENAL
                     FNRLRADGDQIFPLGWAMILQRAGGTHFIADAVAQSANGVFVSLPDVEDVDNADINQR
                     LLEVIEQIGSYSRQIRSAIEDGVVEPHEKTAINDELYLSISKLQEHAALVYKIFCISE
                     SNDARECAAPGAVACRDCGETNA"
     gene            30745..30924
                     /locus_tag="RN951_000989"
     CDS             30745..30924
                     /locus_tag="RN951_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001761574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="HDX2526026.1"
                     /translation="MRQVNRWFKDHYGVPVRVIRWEPETQRVIYLREGYEHECFSPLE
                     QFRRKFREIEVGHEH"
     gene            30914..31855
                     /locus_tag="RN951_000990"
     CDS             30914..31855
                     /locus_tag="RN951_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000104949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX2526027.1"
                     /translation="MSTKLTGYVWDGCAASGMKLSSVAIMARLADFSNDEGVCWPSIE
                     TIARQIGAGMSTVRTAIARLEAEGWLTRKARRQGNRNASNVYQLNVAKLQAAAFSQLS
                     DSDPSKSDASKSDTSKFDASKSGKKAGFHPSESGGDPSVKSKHDPSDKKPSRPDASQP
                     DTQTAEQDFLTRHPDAVVFSPKKRQWGTQDDLTCAQWLWKKIIALYEQAAECDGEVVR
                     PKEPNWTAWANEIRLMCVQDGRTHKQICEMYSRVSRDPFWCRNVLSPSKLREKWDELS
                     LRLSPSVSTHTEKREDPYFKASYDNVDYSQIPAGFRG"
     gene            31852..32346
                     /locus_tag="RN951_000991"
     CDS             31852..32346
                     /locus_tag="RN951_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PerC family transcriptional regulator"
                     /protein_id="HDX2526028.1"
                     /translation="MIMSLLNEVQKFIEAHPGCTSGDIADAFAGYSRQRVLQSASKLR
                     QSGRVAHRCEGDTRRHFPRLTERAQEPEPQPVRETRPVRNFYVGTNDPRVILCLTRQA
                     EELESRGLYRRAATVWMAAFRESYSQPERNNFLARRERCLRKSSKRAASGEEWYLSGN
                     YVGA"
     gene            32346..32672
                     /locus_tag="RN951_000992"
     CDS             32346..32672
                     /locus_tag="RN951_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003878599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HDX2526029.1"
                     /translation="MTTLTQCQQQVLDMLISYQKERGFPPTNQEVATMLGYRSVNAAV
                     EHLRALEKKGVITIKRGVARGITLHTAVKDDDSEAVGIIRSLLADEENARLRATHWLH
                     ERGLKV"
     gene            32669..33057
                     /locus_tag="RN951_000993"
                     /pseudo
     CDS             32669..33057
                     /locus_tag="RN951_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767134.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
     gene            33077..33886
                     /locus_tag="RN951_000994"
     CDS             33077..33886
                     /locus_tag="RN951_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KilA-N domain-containing protein"
                     /protein_id="HDX2526030.1"
                     /translation="MNNLMVIDGIEVRRDAYGRYSLNDLHRAAVASGANARTKEPGKF
                     LSSQQTVELVHELTNTQNLGVDPVSVIHGGNERGTYVCKELVYAYAMWISPSFHLKVI
                     RTFDMVTSAPEKLSGQAADKMQAGVILLDFMRRELNLSNSSVLGACQKLQEAVGLPNL
                     APRYAIDAPADAPDGSSRPTLSLSALLKQYGIRLTANQAYHQMAKLGIVEQRERYSRT
                     AINNIKKFWSLTAKGCMFGKNITSPANPRETQPHFFESRFPELLKLLDTVH"
     gene            33894..34883
                     /locus_tag="RN951_000995"
     CDS             33894..34883
                     /locus_tag="RN951_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001764249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HDX2526031.1"
                     /translation="MRALLTPEIAPRMGIVLFRPGSELMPLFMQGRVLLEPEPERYSS
                     FASGAVPAASQPLADDPAVRAVFRNEAVIRRAGGVECLESWLLREKGCQWPHSDWHSE
                     NMTTMRHAPGAIRLCWHCDNQLRDQFTERLESMATDNCARWVLSVVRRDLGFDDSHVV
                     TMPELCWWLIRNDLADALPESAARKALRLPKPVVPSVTRESDLVPSVPATSIIQDKAK
                     KVLALKVDPESPESFMLRPKRRRWVNEKYTRWVKTQPCACCGKPADDPHHLIGHGQGG
                     MGTKAHDLFVLPLCRKHHDELHADTVAFEEKYGSQLELIFRFIDRALAIGVLA"
     gene            34897..35649
                     /locus_tag="RN951_000996"
     CDS             34897..35649
                     /locus_tag="RN951_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416077.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
                     /protein_id="HDX2526032.1"
                     /translation="MNLEALPKYYSPKSPKLSDDAPATGSGGLTITDVMAAQGMVQSK
                     APLGFALFLAKVGVQDPQFAIEGLLNYAMALDNPTLNKLSEETRLQIIPYLVNFAFAD
                     YSRSAASKARCEHCAGTGFHNVLREVVKHSRSGESVIKEEWVKELCQHCHGKGEVSTA
                     CRGCKGKGLVLDEKRTRLHGTPVYKICGRCNGNRFSRLPTTLARHHVQKLVPDLTDYQ
                     WYKGYTDVIDKLVTKCWQEEAYAEIQLRNVTR"
     gene            35930..36355
                     /locus_tag="RN951_000997"
     CDS             35930..36355
                     /locus_tag="RN951_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000217632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526033.1"
                     /translation="MTVMKKVLIAAIGFCLVGCAGMKLPEYSQVKASPYYTDCRAFAM
                     DVYKNDGYSKIAKTTILSMDDVKARYIVTGCVVAMGKNTVEEIKADLSAKGSSFGLIS
                     GACSSAACRVDVEQQMNAYVLGSYYAANKKFPDKMKAEF"
     gene            36579..36782
                     /locus_tag="RN951_000998"
     CDS             36579..36782
                     /locus_tag="RN951_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526034.1"
                     /translation="MLKQQDMTETAAAVLHFLPADKWVTPRMMTRTTGVSEARCQLIL
                     TQLVLAGLAKDNGGYGNKFRRCQ"
     gene            36933..37985
                     /locus_tag="RN951_000999"
     CDS             36933..37985
                     /locus_tag="RN951_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HDX2526035.1"
                     /translation="MKNTVKINSVDLINADCLHFIQSLPDDSIDLIVTDPPYFKVKPN
                     GWDNQWKGDEDYLKWLDHCLAQFWRVLKPAGSLYLFCGHRLASDIEIMMRERFNVLNH
                     IIWAKPSGRWNGCNKESLRAYFPATERVLFAEHYQGPYRGKSDGYAAKERELKQHIMA
                     PLISYFRDARAELGITAKQIAEATGKKNMVSHWFGASQWQLPNEADYRKLQALFSRIA
                     AEKFQEQQLEQPHHQLVASYDSLNRKYSELLDEFKSLRRYFSVSVSVPYTDVWMHKPV
                     QFYPGKHPCEKPADMLRQIINASSRPGDLVADFFMGSGSTIKAAMALGRRALGVELES
                     ERFNQTVKEINELVGK"
     gene            38053..38268
                     /gene="essD"
                     /locus_tag="RN951_001000"
     CDS             38053..38268
                     /gene="essD"
                     /locus_tag="RN951_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage lysis protein EssD"
                     /protein_id="HDX2526036.1"
                     /translation="MKSMDKLTTGVAYGTSAGSAGYWFLQLLDKVTPSQWAAIGVLGS
                     LVFGLLTYLTNLYFKIKEDKRKAARGE"
     gene            38268..38765
                     /gene="rrrD"
                     /locus_tag="RN951_001001"
     CDS             38268..38765
                     /gene="rrrD"
                     /locus_tag="RN951_001001"
                     /EC_number="3.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme RrrD"
                     /protein_id="HDX2526037.1"
                     /translation="MPPSLRKAVAAAIGGGAIAIASVLITGPSGDDGLEGVSYIPYKD
                     IVGVWTVCHGHTGKDIMLGKTYTEAECKALLNKDLATVARQINPYIKVDIPETTRGAL
                     YSFVYNVGAGNFRTSTLLRKINQGDIKGACDQLRRWIYAGGKQWKGLMTRREIEREVC
                     LWGQQ"
     gene            38762..39229
                     /locus_tag="RN951_001002"
     CDS             38762..39229
                     /locus_tag="RN951_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HDX2526038.1"
                     /translation="MSRVTAIISALVICIIVCLSWAVNHYRDNAIAYKEQRDKKVSEL
                     KQATATITDMQQRQRSADALDAKYTKELADAKAENDALRRKLDNGGRVFVKGKCPVPS
                     SAETSSASGMGNDATVELSPVAGRNVLGIRDGIIRDQTALRTLQEYIRTQCLR"
     gene            39217..39369
                     /locus_tag="RN951_001003"
     CDS             39217..39369
                     /locus_tag="RN951_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526039.1"
                     /translation="MPSMIAIILLIILHIWLCRQDGDHFWSESRLNISLLMLDIEHLA
                     RGKGLR"
     gene            complement(39721..40131)
                     /locus_tag="RN951_001004"
     CDS             complement(39721..40131)
                     /locus_tag="RN951_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1398 family protein"
                     /protein_id="HDX2526040.1"
                     /translation="MAQVAIFKQIFDKVRNNLNYHWFYSELKRHNVSHYIYYLATENI
                     HLVLENDNTVLIKGQGKVVNVRFSKNKCLIEATLKGFKSGELSFYEYRKNLATAGVFR
                     WITNIHENKRYYYTFDNSLLFTENIQNTTQIFPH"
     gene            complement(40188..40421)
                     /locus_tag="RN951_001005"
     CDS             complement(40188..40421)
                     /locus_tag="RN951_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcI/YnfO family protein"
                     /protein_id="HDX2526041.1"
                     /translation="MSTKNRTRRTTTRNIRFPNQMIEQINIALDQKGSGNFSAWVIEA
                     CRRRLCSEKRVSPEANKEKSDITELLRKQIRPD"
     gene            40810..41355
                     /locus_tag="RN951_001006"
     CDS             40810..41355
                     /locus_tag="RN951_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein"
                     /protein_id="HDX2526042.1"
                     /translation="MEVNKKQLADIFGASIRTIQNWQEQGMPVLRGGGKGNEVLYDSA
                     AVIKWYAERDAEIENEKLRREVEELRQASETDLQPGTIEYERHRLTRAQADAQELKNA
                     RDSAEVVETAFCTFVLSRIAGEIASILDGIPLSVQRRFPELENRHVDFLKRDIIKAMN
                     KAAALDELIPGLLSEYIEQSG"
     gene            41330..43255
                     /locus_tag="RN951_001007"
     CDS             41330..43255
                     /locus_tag="RN951_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit family protein"
                     /protein_id="HDX2526043.1"
                     /translation="MNISNSQVNRLRHFVRAGLRSLFRPEPQTAVEWADANYYLPKES
                     AYQEGRWETLPFQRAIMNAMGSDYVREVNVVKSARVGYSKMLLGVYAYFIEHKQRNTL
                     IWLPTDGDAENFMKTHVEPTIRDIPSLLALAPWYGKKHRDNTLTMKRFSNGRGFWCLG
                     GKAAKNYREKSVDVAGYDELAAFDEDIEQEGSPTFLGDKRIEGSVWPKSIRGSTPKVR
                     GTCQIERAASESPHFMRFHVACPHCGEEQYLKFGDKETPFGLKWTPDDPSSVFYLCEH
                     NACVIRQQELDFTDARYICEKTGIWTRDGILWFSSSGEEIEPPDSVTFHIWTAYSPFT
                     TWVQIVKDWMKTKGDTGKRKTFVNTTLGETWEAKIGERPDAEVMAERKEHYSAPVPDR
                     VAYLTAGIDSQLDRYEMRVWGWGPGEESWLIDRQIIMGRHDDEQTLLRVDEAINKTYT
                     RRNGAEMSVSRICWDTGGIDPTIVYERSKKHGLFRVIPIKGASVYGKPVASMPRKRNK
                     NGVYLTEIGTDTAKEQIYNRFTLTPEGDEPLPGAVHFPNNPDIFDLTEAQQLTAEEQV
                     EKWVDGRKKILWDSKKRRNEALDCFVYALAALRISISRWQLDLSALLASLQEEDGAAT
                     NKKTLADYARALSGEDE"
     gene            43252..43458
                     /locus_tag="RN951_001008"
     CDS             43252..43458
                     /locus_tag="RN951_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gpW family protein"
                     /protein_id="HDX2526044.1"
                     /translation="MTRQEELAAARAALHDLMTGKRVATVQKDGRRVEFTATSVSDLK
                     KYIAELEVQTGMTQRRRGPAGFYV"
     gene            43455..45056
                     /locus_tag="RN951_001009"
     CDS             43455..45056
                     /locus_tag="RN951_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDX2526045.1"
                     /translation="MKTSTIPTLLGPDGMTSLREYAGYHGGGSGFGGQLRAWNPPGES
                     VDAALLPNFTRGNARADDLVRNNGYAANAIQLHQDHIVGSFFRLSHRPSWRYLGIGEE
                     EARAFSREVESAWKEFAEDDCCCIDVERKRTFTMMIREGVAMHAFNGELFVQATWDTS
                     PSRLFRTQFRMVSPKRISNPNNTGDSRNCRAGVQINDSGAALGYYVSEDGYPGWMPQK
                     WTWIPRELPGGRASFIHVFEPVEDGQTRGANVFYSVMEQMKMLDTLQNTQLQSAIVKA
                     MYAATIESELDTQSAMDFILGANSQEQRERLTGWIGEIAAYYAAAPVRLGGAKVPHLM
                     PGDSLNLQTAQDTDNGYSVFEQSLLRYIAAGLGVSYEQLSRNYAQMSYSTARASANES
                     WAYFMGRRKFVASRQASQMFLCWLEEAIVRRVVTLPSKARFSFQEARSAWGNCDWIGS
                     GRMAIDGLKEVQEAVMLIEAGLSTYEKECAKRGDDYQEIFAQQVRETMERRTAGLKPP
                     AWAAAAFESGLRQSTEEEKSDSRAA"
     gene            45037..46356
                     /locus_tag="RN951_001010"
     CDS             45037..46356
                     /locus_tag="RN951_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S49 family peptidase"
                     /protein_id="HDX2526046.1"
                     /translation="MTAELRNLPHIASMAFNEPLMLEPAYARVFFCALAGQLGISRLT
                     DAVSGDSLTAGEAPAALALSGDDDGPRQARSYQVMNGIAVLAVSGTLVSRTRALQPYS
                     GMTGYNGIIARLQQAASDPMVDGILLDMDTPGGMVAGAFDCADIIARVRDIKPVWALA
                     NDMNCSAGQLLASAASRRLVTQTARTGSIGVMMAHSNYGAALEKQGVEITLIYSGSHK
                     VDGNPYSHLPDDVRETLQSRMDATRRMFAQKVSAYTGLSVQAVLDTEAAVYSGQEAID
                     AGLADELVNSTDAITVMRDALDARKSRLSGGRMTKETQSTTVSATASQADVTDVVPAT
                     EGENASAAQPDVNAQITAAVAAENSRIMGILNCEEAHGREEQARVLAETPGMTVETAR
                     RILAAAPQSAQARSDTALDRLMQGAPAPLAAGNPASDAVNDLLNTPV"
     gene            46366..46698
                     /locus_tag="RN951_001011"
     CDS             46366..46698
                     /locus_tag="RN951_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HDX2526047.1"
                     /translation="MTSKETFTHYQPLGNSDPAHTATAPGGLSKKTPAMTPLMPDTST
                     RKLVAWDGTTDGAAVGILAVAADQTSTTLTFYKSGTFRYEDVLWPEAASDEAKKRTAF
                     AGTAISIV"
     gene            46754..47779
                     /locus_tag="RN951_001012"
     CDS             46754..47779
                     /locus_tag="RN951_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HDX2526048.1"
                     /translation="MSMYTTAQLLAANEQKFKFDPLFLRLFFRESYPFTTEKVYLSQI
                     PGLVNMALYVSPIVSGEVIRSRGGSTSEFTPGYVKPKHEVNPQMTLRRLPDEDPQNLA
                     DPAYRRRRIIMQNMRDEELAIAQVEEMQAVSAVLKGKYTMTGEAFDPVEVDMGRSEAN
                     NITQSGSTGWSKRDKSTYDPTDDIEAYALNASGVVNIIVFDPKGWALFRSFKAVREKL
                     DTRRGSHSELETAVKDLGKAVSYKGMYGDVAIVVYSGQYVENGVKKNFLPDNTMVLGN
                     THARGLRTYGCIQDADALSEGINASPRYPKNWKTSGDPAREFTMIQSAPLMLLADPDE
                     FVSVQLA"
     gene            47821..48216
                     /locus_tag="RN951_001013"
     CDS             47821..48216
                     /locus_tag="RN951_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein FI"
                     /protein_id="HDX2526049.1"
                     /translation="MTKDELIARLRSLGEQLNRDVSLTGTKEELALRVAELEEELDDT
                     DDAAGQDTSVSPENVLTVHENEVVSAQPDTVTDTADLVTVVALVTLHTDALHATRDEA
                     VAFVLPGTAFRVSAGVAAEMTERGLARMQ"
     gene            48228..48581
                     /locus_tag="RN951_001014"
     CDS             48228..48581
                     /locus_tag="RN951_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail joining protein"
                     /protein_id="HDX2526050.1"
                     /translation="MADFDNLFDAAIACADETIRGYMGTSATMTSGEQSGAVIRGVFD
                     DPENISYAGQGVRVEGSSPSLFVRTDDVRQLRRGDMLTIGEENFWIDRISPDDGGSCH
                     LWLGRGVPPAVNRRR"
     gene            48593..49171
                     /locus_tag="RN951_001015"
     CDS             48593..49171
                     /locus_tag="RN951_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX2526051.1"
                     /translation="MAIKGLEQAVENLSRISRTAVPGAAAMAINRVASSAISQSASQV
                     ARETKVRRKLVKERARLKRATVKNPQARIKVNRGDLPVIRLGNARVVLSRRRRRKKGQ
                     RSSLKGGGSVLVVGNRRIPGAFIQQLKNGRWHVMQRVAGKNRYPIDVVKIPMAVPLTT
                     AFKQNIERIRRERLPKELGYALQHQLRMVIKR"
     gene            49168..49563
                     /locus_tag="RN951_001016"
     CDS             49168..49563
                     /locus_tag="RN951_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX2526052.1"
                     /translation="MKHTELRAAVLDALEKHDTGATLFDGRPAAFDEEDFPAIAVYLT
                     GAEYTGEELDSDTWQAELHIEVFLPAQVPDSELDSWMESRIYPVMSDIPALSDLITSM
                     VASGYDYRRDDDAGLWSSADLTYVITYEM"
     gene            49571..50311
                     /locus_tag="RN951_001017"
     CDS             49571..50311
                     /locus_tag="RN951_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX2526053.1"
                     /translation="MPTPNPLAPVKGAGTTLWVYNGSGDPYANPLSDVDWSRLAKVKD
                     LTPGELTAESYDDSYLDDENADWTATGQGQKSAGDTSFTLAWMPGEQGQQALLAWFNK
                     GDTRAYKIRFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGRPSMAEDRSTVTA
                     ATGMTVTPASTSVVKGRSITLTVAFQPEGATDKSFRAVSADKTKATVSVSGMTITVKG
                     VAAGKVNIPVVSGNGELAVVAGITVTDS"
     gene            50327..50749
                     /locus_tag="RN951_001018"
     CDS             50327..50749
                     /locus_tag="RN951_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein G"
                     /protein_id="HDX2526054.1"
                     /translation="MFLKTESFEYNGMSVTLSELSALQRIEHLALLKRQAEQAGSSLN
                     RQVSVEDLVRTGAFLVAMSLWHNHPQKTKMPSMNEAVKQIEQEVLTTWPTEAIAQAEN
                     VVMRLSGMSEFVVNDAPEQAEDAGPAEPVSAGKCSTVS"
     gene            50731..51165
                     /locus_tag="RN951_001019"
     CDS             50731..51165
                     /locus_tag="RN951_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein T"
                     /protein_id="HDX2526055.1"
                     /translation="MFDGELSFALKLAREMGRPDWRAMLAGMSSTEYADWHRFYSTHY
                     FHDVLLDMHFSGLTYTVLSLFFSDPDMHPLDFSLLNRREADEEPEDDVLMQKAAGLAG
                     GVRFGPDGNEVIPTSPDVADMTEDDVMLMTVSEGIAGGVRYG"
     gene            51158..53737
                     /locus_tag="RN951_001020"
     CDS             51158..53737
                     /locus_tag="RN951_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDX2526056.1"
                     /translation="MAEPVGDLVVDLSLDAARFDEQMARVRRHFSGTETDAKKTAAVV
                     EQSLSRQALAAQKAGISVGQYKAAMRMLPAQFTDVATQLAGGQSPWLILLQQGGQVKD
                     SFGGMIPMFRGLAGAITLPMVGATSLAVATGALAYAWYQGNSTLSDFNKTLVLSGNQA
                     GLTADRILALSRAGQAAGLTFNQTSESLTALVNAGVRGGEQFEAISQSVARFSSASGV
                     EVDKVAEAFGKLTTDPTSGLTAMARQFRNVTAEQIAYVAQLQRSGDEAGALQAANEAA
                     TKGFDDQTRRLKENMGTLETWADRTARAFKSMWDSVLDIGRPDTAQGMLEKAEKAFDE
                     ADKKWQWYQSRSHRRGKTSAFLANLRGAWEDRANAQLGLSAATLQADLEKAREMAAKD
                     WAESEASRLKYTEEAQKAYERLQTPLEKYTARQEELNKALKDGKILQADYNTLMAAAK
                     KDYEATLKKPKQSGVKVSAGDRQEDSAHAALLTLQAELRTLEKHAGANEKISQQRRDL
                     WKAESQFAVLEEAAQRRQLSAQEKSLLAHKDETLEYKRQLAALGDKVTYQERLNALAQ
                     QADKFAQQQRAKRAAIDAKSRGLTDRQAEREATEQRLKEQYGDNPLALNNVMSEQKKT
                     WAAEDQLRGNWMAGLKSGWSEWEESATDSMSQVKSAATQTFDGIAQNMAAMLTGSEQN
                     WRSFTRSVLSMMTEILLKQAMVGIVGSIGSAIGGAVGGGASASGGTAIQAAAAKFHFA
                     TGGFTGTGGKYEPAGIVHRGEFVFTKEATSRIGVGNLYRLMRGYATGGYVGTPGSMAD
                     SRSQASGTFEQNNHVVINNDGTNGQIGPQALKAVYDVARKAAMDVVTGQMRDGGLFSG
                     GGR"
     gene            53734..54063
                     /locus_tag="RN951_001021"
     CDS             53734..54063
                     /locus_tag="RN951_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX2526057.1"
                     /translation="MKTFRWKVKPGMDVASVPSVRKVRFGDGYSQRAPAGLNANLKTY
                     SVTLSVPREEATVLESFLEEHGGWKSFLWTPPYEWRQIKVTCAKWSSRVSMLRVEFSA
                     EFEQVVN"
     gene            54063..54761
                     /locus_tag="RN951_001022"
     CDS             54063..54761
                     /locus_tag="RN951_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HDX2526058.1"
                     /translation="MQDIRQETLNECTRAEQSASVVLWEIDLTEVGGERYFFCNEQNE
                     KGEPVTWQGRQYQPYPIQGSGFELNGKGTSTRPTLTVSNLYGMVTGMAEDMQSLVGGT
                     VVRRKVYARFLDAVNFVNGNSYADPEQEVISRWRIEQCSELSAVSASFVLSTPTETDG
                     AVFPGRIMLANTCTWTYRGDECGYHGPAVADEYDQPTSDITKDKCSKCLSGCKFRNNV
                     GNFGGFLSINKLSQ"
     gene            54767..55510
                     /locus_tag="RN951_001023"
     CDS             54767..55510
                     /locus_tag="RN951_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX2526059.1"
                     /translation="MTETESAILAHARRCAPAESCGFVVKTPEGERYFPCVNISGEPE
                     EYFRMSPEDWLRAEMQGEIVALVHSHPGGLPWLSEADRRLQVQSDLPWWLVCRGAIHK
                     FRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGIEMPDFHRGDDWWRNGQNLYLDNLEAT
                     GLYQVPLSAAQPGDVLLCCFGSSVPNHAAIYCGDGELLHHIPEQLSKRERYTDKWQRR
                     THSLWRHRAWHASAFTGICNDLAAASIFV"
     gene            55408..56055
                     /locus_tag="RN951_001024"
     CDS             55408..56055
                     /locus_tag="RN951_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HDX2526060.1"
                     /translation="MAATHTLPLASPGMARICLYGDLQRFGRRIDLRVKTGAEAIRAL
                     ATQLPAFRQKLNKGWYQVRIAGRDAGENELSARLNEPLANGAVIHIVPRLAGAKSGGV
                     FQVVLGAALIAVAWWNPVGWLGAAAVSGMYAAGASMILGGVAQMLAPKARTPTAASTD
                     NGKQNTYFSSLDNMVAQGNVLPVLYGEMRVGSRVASQEISTADEGDGGQVVVIGR"
     gene            56116..59613
                     /locus_tag="RN951_001025"
     CDS             56116..59613
                     /locus_tag="RN951_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HDX2526061.1"
                     /translation="MGKGSSKGHTPREAKDNLKSSQMLSVIDAISEGPIEGPVDGLKS
                     VLLNSTPVLDSEGNTNISGVTVVFRAGEQEQTPPEGFESSGSETVLGTEVKYDTPITR
                     TITSANIDRLRFTFGVQALVETTSKGDRNPSEVRLLVQIQRNGGWVTEKDITIKGKTT
                     SQYLASVVVGNLPPRPFNIRMRRMTPDSTTDQLQNKTLWSSYTEIIDVKQCYPNTALV
                     GVQVDSEQFGSQQVSRNYHLRGRILQVPSNYNPQTRQYSGIWDGTFKPAYSNNPAWCL
                     WDMLTHPRYGMGKRLGAADVDKWALYVIGQYCDQSVPDGFSGTEPRITCNAWLTTQRK
                     AWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDKVWTYNRSNVVMPDDGAPFRYSFSAL
                     KDRHNAVEVNWIDPDNGWETATELVEDTQAIARYGRNVTKMDAFGCTSRGQAHRAGLW
                     LIKTELLETQTVDFSVGAEGLRHVPGDVIEICDDDYAGIRTGGRVLAVNIQTRTLTLD
                     REITLPSSGTTLISLVDGQGSPVSVEVQSVTDGVKVKVSRVPDGVAEYSVWGLKLPTL
                     RQRLFRCVSIRENDDGTYAITAVQHVPEKEAIVDNGAHFDGDQSGTVNGVTPPAVQHL
                     TAEVTADSGEYQVLARWDTPKVVKGVSFLLRLTVAADDGRERLVSTARTTETTYRFTQ
                     LALGNYRLTVRAVNAWGQQGDPASVSFRIAAPAAPSRIELTPGYFQITATPHLAVYDP
                     TVQFEFWFSEKRIADIRQVETSARYLGTALYWIAASINIKPGHDYYFYVRSVNTVGKS
                     AFVEAVGQPSDDASGYLDFFKGEIGKTHLAQELWTQIDNGQLAPDLTEIRTSITDVSN
                     EITQTVNKKLEDQSAAIQQIQKVQVDTNNNLNSMWAVKLQQMQDGRLYIAGIGAGIEN
                     TPDGMQSQVLLAADRIAMINPANGNTKPMFVGQGDQIFMNEVFLKRLTAPTITSGGNP
                     PAFSLTSDGRLTAKNADISGSVNANSGTLNNVTINQNCTIKGMLEATQVRGDFVKAVS
                     KAFPKKVGTWGNTETPNGTVTVTISDDHNFDRQIIIPPIIFNGIAYDDPGSGNNPGGT
                     RYTGYGFEVRKNGVLIASRETKGAIPGSYSAVIDMPSGRGSVTLEFKIFQKGNQGAGN
                     ITDCTVIVTKKAASGISIR"
     gene            59684..60283
                     /locus_tag="RN951_001026"
     CDS             59684..60283
                     /locus_tag="RN951_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ail/Lom family outer membrane beta-barrel
                     protein"
                     /protein_id="HDX2526062.1"
                     /translation="MRKVCAAILSAAICLAVSGAPAWASEHQSTLSAGYLHASTNVPG
                     SDDLNGINVKYRYEFTDTLGLVTSFSYAGDKNRQLTRYSDTRWHEDSVRNRWFSVMAG
                     PSVRVNEWFSAYAMAGVAYSRVSTFSGDYIRVTDNKGKTHDVLTGSDDGRHSNTSLAW
                     GAGVQFNPTESVAIDVAYEGSGSGDWRTDGFIVGVGYKF"
     gene            60348..62483
                     /locus_tag="RN951_001027"
                     /pseudo
     CDS             60348..62483
                     /locus_tag="RN951_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309677.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prophage tail fiber N-terminal domain-containing
                     protein"
     gene            63377..63787
                     /locus_tag="RN951_001028"
     CDS             63377..63787
                     /locus_tag="RN951_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDX2526063.1"
                     /translation="MNKFYKGSFYPKALKEVYISAGSWPENGVDVDDETMAIYTGVAP
                     QGKTLGADKNGNPAWIDIPPLSAEQQIIQAEQKRTVLRSMADKEIAWRQDAFDAEIAT
                     AEETAALSEWKKYRVLLMRVDTAKPVWPVNPQDI"
     gene            complement(63768..64001)
                     /locus_tag="RN951_001029"
     CDS             complement(63768..64001)
                     /locus_tag="RN951_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001340317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526064.1"
                     /translation="MENMYFSPTTVGFYVSEQERPDDAVEVSPEVEAFLRECVIWGAD
                     TFNVERDAATVTYPTELLEYVTTYNAPVKYPAD"
     gene            complement(64370..64477)
                     /locus_tag="RN951_001030"
                     /pseudo
     CDS             complement(64370..64477)
                     /locus_tag="RN951_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683159.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
     gene            64507..64794
                     /locus_tag="RN951_001031"
                     /pseudo
     CDS             64507..64794
                     /locus_tag="RN951_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            64929..65999
                     /locus_tag="RN951_001032"
     CDS             64929..65999
                     /locus_tag="RN951_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001730411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RnlA family
                     toxin"
                     /protein_id="HDX2526065.1"
                     /translation="MTVRNYTNLNLDRTTIEATSRAFIENKNYSVHSIGPMPGARAGL
                     RVVFAKPGEALATVNIFYNNGGTSTVQYQTGANHNLGKELADDLYETINPAEFEQVNM
                     VLQGFVEANVLSVLQLSAEQPHIQFYEYLRNTHTTVWKIHSPEFQDELTVSLHHRNGT
                     LQIQGRPLSCYRVFIFNLSELLDLQGLEKVLIRQDDGKAYIVQKEVARSHLECEMGDA
                     YPLLHKNVEKLLVSGLCVKLAAPDLPDYCMLLYPELRSVEGVLKSTMYRYGMPITQDG
                     FGRYFDKIGSEFILKQQFGCNLSSAKVKTINDAYTFFNRERHGLFHMEIVVDTSRMVS
                     DMARLMTKARQAWGIIKDLYIV"
     gene            65992..66354
                     /locus_tag="RN951_001033"
     CDS             65992..66354
                     /locus_tag="RN951_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RnlB family
                     antitoxin"
                     /protein_id="HDX2526066.1"
                     /translation="MFEITGVNVSGALIAVVMATGYENPLTSVHEIEKRLSVILGNSQ
                     ATGEVLFDLLCSNGPEWNRFVSLEIRCGSILLDTAKIVDEQEIPAQILRHQRDVLRNH
                     PEYVEDSVLTPDDVLCIL"
     gene            complement(66492..66761)
                     /locus_tag="RN951_001034"
     CDS             complement(66492..66761)
                     /locus_tag="RN951_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526067.1"
                     /translation="MENLLFVMCWIKDHHVMSLTFGVLSAILWIKSATAKVELGKKIV
                     MVTYEDPELNVNLHDFFATARLQSKYNSFAALSAAATALFQIIGL"
BASE COUNT        16672 a        16389 c        18319 g        15951 t
ORIGIN      
        1 gaacataaat tgtcagatat tctactgttg actatttgtg ccgttatttc tggtgcagaa
       61 ggctgggaag atatagagga ttttggggaa acacatctcg attttttaaa acaatatggt
      121 gattttgaaa atggtattcc tgttcacgat accatcgcca gagttgtatc ctgtatcagt
      181 ccttcaaaat ttcacgagtg ctttattaac tggatgcgag attgccatac ttcagatgat
      241 aaagacgtca tcgcaattga tggaaaaaca ctccggcatt cttatgacaa gagtcgccgc
      301 aagggagcga ttcatgtcat tagtgcgttc tcaacaatgc acagtctggt catcggacag
      361 atcaggacgg atgagaaatc caatgagatt acagctatcc ctgaacttct taacatgctg
      421 gatattaaag gaaaaatcat cacaactgat gcgatgggtt gccagaaaga tattgcagag
      481 aagatacaaa aacagggagg tgattattta ttcgcggtaa aaggaaacca ggggcggcta
      541 aataaagcct tcgaggaaaa atttccgctg aaagaattaa ataatccaga gcatgacagt
      601 tacgcaatta gtgaaaagag tcacggcaga gaagaaatcc gtcttcacat tgtttgcgat
      661 gtccctgatg aacttattga tttcacattt gaatggaaag ggctgaagaa attatgcgtg
      721 gcagtctcct ttcggtcaat aatagcagaa caaaagaaag agccagaaat gacggtcaga
      781 tattatatca gttctgctga tttaaccgca gagaagttcg ccacagcaat ccgaaaccac
      841 tggcacgtgg agaataagct gcacaggcgt ctggacgtgg taatgaatga agacgactac
      901 aaaataagaa gaggaaacgc agcagaatta ttttcaggga tacggcacat tgctattaat
      961 attttgacga atgagaaggt attcaaggca gggttaagac gtaagatgcg aaaagcagcc
     1021 atggacagaa actacctggc gtcagtcctt gcggggagcg ggctttcgta gtaatacccc
     1081 gactctcccc gtccttaaac acaaccccca ctcaccacaa cctaaactca tccgcatcct
     1141 gccatgccgg aaacttttct ctatattccc gcaatgctgc catcgacagc tccgcatcaa
     1201 tgcgcgttgc ctgatgcgcg tcggcagtag cgataatctc tccttgcgga ttaatcaccc
     1261 ggctgtcacc gcgataatgg cagccgttgc catcgctgcc gacgcgattg catcccgcca
     1321 catacgcctg attctcaatc gcgcgggccg tcagcaatgc ctgccagtgc agagagcgcg
     1381 gagcaggcca gttggcgacg tacagggcga ggtcataatc gttgagattg cgcgaccaca
     1441 caggaaaacg taagtcgtag cacaccagcg gcaaaatacg ccagccgcgc cattccacaa
     1501 tcactcgcgc attgcccgct ttataatgta gatgctcatc tgccatgcgg aacagatgac
     1561 gcttatcata aaaatgtacc gtgccgcccg gctcaaccag caaaaagcgg ttaaccgaac
     1621 cagactccgt ttgtaatgca acactgcctg caatcagcgc attgcactgc tgcgccttag
     1681 ctgtcatcca gttcactacg tcatcttgtg ctagcgacga agctgccgct tccatggcaa
     1741 agccgctggt aaacatctcc ggtagaacga tcacatcgcg cccggtaata ccttccagtt
     1801 gacgatcaaa atgacgcagg ttggcaggac catccatcca caccagtggt tgctgcaaaa
     1861 gcgtaatctt caaaccaggc acggtgtaca actcctttat gcgaagggtt ttataacttt
     1921 aacaccttat caggcagttg ccttagcgca gaataaattg ataacaaatg ctgatattgg
     1981 aaatatctga tttgcaaatt atcgtgttat cgccaggctt taggaggtta ataacatggg
     2041 caggataagc tcgggaggaa tgatgtttaa ggcaataacg acagtcgccg ctctggtcat
     2101 cgccaccagt gcaatggcgc aggatgattt aaccattagc agccttgcaa agggcgaaac
     2161 caccaaagct gcatttaatc agatggtaca agggcataag ctgcctgcct gggtgatgaa
     2221 aggcggtact tatactcccg cacaaaccgt aacgttggga gatgagacgt atcaggtgat
     2281 gagcgcgtgc aaaccgcatg actgtggctc gcaacgtatc gctgtgatgt ggtccgagaa
     2341 atctaatcag atgacggggc tgttctcgac tattgatgag aaaacgtcgc aagagaaact
     2401 cacttggctg aatgtgaacg atgcgctttc gattgatggt aaaacggtgt tgttcgcggc
     2461 gttgaccggc agcctggaaa accatccgga tggctttaat tttaaataat tagcggataa
     2521 agaaacggag cctttcggct ccgttattca tttacgcggc ttcaactttc cgcactttct
     2581 ccggcaactt taccggcttc gtcgccagct cttccggatc aaagtcatca acgttaatac
     2641 tgcgcagacg gctttcttca gctttcacca gaatagcggc ttcatcttta tcaatcagcc
     2701 ccttcaccag cgcgttgtgc gccagttcat ccagacgggt aaacggcagg tttttaccca
     2761 gctctttaca gatccgctga tgaattgggt cggcggcaat cacatccacc agcgcctctt
     2821 ccagcaagcc aaccggatta tgctcgctcg gcgtcaggta ctgaccgcga ccaatgcggg
     2881 aacgggtggc gttcggcact tgtaaaatct tcgccacttt atgatccagc ttgtcagaag
     2941 gtgccagata atgacgtccg gtcgggaaga tcaccacatt cagcagcccg gcaaccacgc
     3001 ggttcgggaa gttttgcagt aaatcatcca tcgcctgttc agcctgatac agcgcatctt
     3061 gtacgcccca gtgcaccagc ggcaggtcgg cttcattacg gccttcgtcg tcataacgct
     3121 tcagcacggc agaggcgagg tagagctggc ttaaaatatc ccccagacgg gccgagatgc
     3181 gctcgcgacg tttcaggctg ccgcccagca ctgccatcga gacatcagaa agcagggcga
     3241 ggttggcgct caggcggttc aggtgctgat agtagcgttt agtggcatcg ccggttggcg
     3301 tgctgctggt taaaccgcgc gtcaggccca gccagaagct gcgaactttg ttgctaccga
     3361 cgtgaccgat atgtttgaac aacagtttat cgaacgcgtt gacgtcattg ttcttcgccg
     3421 cttccatctc ttccagcacg tacggatggc aacgaatcgc tccttgtccg aagatcatca
     3481 tgctgcgggt cagaatgtta gccccttcaa cggtgatggc aatcggtgcg ccctggtaag
     3541 cacgcgccag gaagttgctt tgcccgagca taatgccttt accgccggta atatccatcg
     3601 catcaataat cgactgctgc ccgcggtggg tacagtgata cttaacgata gccgacagca
     3661 cggcaggttt ttcgccgagc ataatgccgt aggtaatcag cgatgccgca gcatccatca
     3721 cgtaggcatt accggcaata cgcgccagcg gctcttcaat cccttccatc ttaccaatag
     3781 agattttgaa ctgacggcga atgtgagcat acgcgccggt tgccagcgct accgatttca
     3841 cgccgccggt tgagttggaa ggcagggtga tgccgcggcc taccgagagg cactccacca
     3901 gcatccgcca gccttgcccg gccattttcg gcccgccgat gatgtaatcg atcggcacga
     3961 agacatcttt accgcgcgtc ggtccgttct ggaacggtac gttcagcggg aagtggcgac
     4021 gaccaatttc cacgcccggc gtggtggttg ggatcagcgc acaggtaatg cctaaatctt
     4081 ctgcaccgcc gagtaatttt tccgggtcgg agagtttaaa cgccagccca agcacggtcg
     4141 caatcggtgc cagcgtaatg tagcgtttgt tccaggtcag acgcatcccc agcacctgct
     4201 ggccctgcca ttcgcccatg cagacaatcc cggtgtccgg aatcgcgccc gcatcggaac
     4261 ccgcttccgg gctggtcagt gcaaagcagg ggatctcctg accacgcgcc agacgcggca
     4321 gatagtgatc tttctgctcg tcagtgccgt aatgttgcaa cagttcgccc gggcctaatg
     4381 agtttggcac gccgacggta atcgccagga tcccgctcac gccggagagt ttttgcagca
     4441 cgcgagactg ggcataagcc gagaactcca gcccgccgta ctcttttttg atgatcatcg
     4501 cgaagaaacg atgctcttta aggtacgccc acaactccgg cggcagatcc gccagctcat
     4561 gggtgatctg gaaatcattc gccatccggc aggcttcttc taccgggccg tcgagaaacg
     4621 cttgctcttc ggcggtcagg cgcggctgcg gatagttatg cagctttttc cagtccggct
     4681 tgccctggaa caagtcgccc tcccaccagg tggtgcccgc atcaatcgct tctttctcag
     4741 tgcgcgacat cggcggcatc accttacgga aaccgcgaaa taccggcgcg gaaatcatcg
     4801 acttacgcat aggcgcaaag ttaaatggca cgaggataat ggccagaggc accagtaccc
     4861 acgccgacca cagaccagca acgccgaggg cggctgtcca ggcgagcaaa atcagactgc
     4921 tgataaataa gctcacgcgg tgatagaaca acgcgccgag caggacaacc gtagcgagaa
     4981 tactcaaaat catcataacg aaaagcccct tacttgtagg aggtctgacc acttgtgatg
     5041 atatggttgt agtggatgta aaaacattta gcaatatgtt tacaatataa ttacaacaaa
     5101 gctcacattg ttgctgtttt tatccgcact tcaggtcaaa aagtcctggt catagcacct
     5161 gcccgtactt ctcgcttttg gcggtatccg gtacactgca ttttgtctat tacatttatg
     5221 ctgaaggata tcctcatgta ccaggatctt attcgtaacg aactgaacga agcggcggaa
     5281 acgctggcta actttttaaa agatgacgcc aatattcacg ccattcagcg cgcggcggtc
     5341 ctgttagcag acagctttaa agccggtggc aaagtgcttt cctgcggcaa cggcggttcc
     5401 cattgcgacg ctatgcactt tgccgaagag ttgaccggtc gctaccgtga aaaccgtccg
     5461 ggctacccgg cgattgctat ttctgacgtt agtcatattt cctgcgtcgg taatgatttc
     5521 ggtttcaatg atattttctc ccgctacgtt gaagcggtag gtcgcgaagg cgatgtactg
     5581 ctggggatct ccacctccgg taactctgca aacgtgatca aagcgatcgc agcggcgcgt
     5641 gagaagggaa tgaaagtgat caccctgacc ggtaaagacg gcggcaaaat ggctggcacg
     5701 gcggatatcg aaattcgcgt accgcacttt ggttatgccg accgcattca ggagattcac
     5761 attaaagtga tccatatcct gatccagttg attgaaaaag agatggttaa gtaagtctgg
     5821 cgtaggccgg ataagacgtt tacgccgcat ccggcatttg tgcgctgatg cctgatgcga
     5881 cgctgacgcg tcttatcatg cctacaaatc tgtacgcgaa ccgtaggccg aataatgcgt
     5941 tcacgccgca tccgacctga aaattcttaa atcaatcttc gccgggggcc atgcgctccc
     6001 gctgttgtgg aggttaccca tgtgcgaatt gctcgggatg agcgccaacg tccctaccga
     6061 tatctgcttt agtttcaccg ggcttgtaca gcgtggtggt ggaaccgggc cacataaaga
     6121 tggctggggc attacctttt acgaaggtaa aggctgtcgc acatttaaag atccacaacc
     6181 cagctttaat tcccccatcg ccaaacttgt ccaggactac ccgataaaat cctgttcggt
     6241 ggtggctcat attcgccagg ctaatcgggg cgaggtggcg ctggaaaata ctcacccatt
     6301 tacccgcgag ttatgggggc gtaactggac ttatgcccat aacggacaac tgacgggcta
     6361 caaatcactg gaaaccggca acttccgccc ggtaggcgaa accgacagcg aaaaagcctt
     6421 ctgctggctc ctgcataaat taacgcagcg ttacccgcgc acaccgggca acatggcggc
     6481 ggtatttaaa tatatcgcct cactggcgga tgaactgcgg cagaagggcg ttttcaacat
     6541 gctgctttcg gacgggcgct atgtaatggc gtattgctcg actaatttac actggatcac
     6601 ccgccgcgcg ccgtttggcg tggcaacgtt gctggatcag gatgtggaaa tcgacttcag
     6661 ctcgcagacc acaccgaatg atgtggtcac ggtgattgca acacagccgc tgacgggcaa
     6721 tgaaacctgg caaaagatta tgccaggcga atggcgctta ttttgcctcg gggagcgtgt
     6781 agtttgatgc cagttgtggc tgcacaactt cgtggcttaa cggcttgctg accacgtaac
     6841 gaccattgac cacagaaacg gttggtggct tacgggtttg ctcaaagtag tcgtaacccg
     6901 gcttcagttg ctcccagaag tccttaaagt tggaatattt atggcgcttc atattggcgt
     6961 cggtcatgcg gaacgggtaa atactcactt gcacgctcgg ctgaccaaac accagcgcac
     7021 cagtaacgaa ctggaatatc tcatcaatac cctgattggt cattgcgtag cagccgatgg
     7081 aaacacaatc gccgtggatc atcaggtatt tcccttcata accatgcgca cggtcatagg
     7141 cattggggaa accaatatta atcgctttgt agtaacggct gtctggtttt aactgattac
     7201 gctggacgct ataaaaccct tccgggcttt tgaaatcgcc ctgacgctgt tttggcccta
     7261 agccgccgga atatttacag attttatagc tgtcgagcag ttgatattgc tcgcccattt
     7321 tgacgtagag atcgagcgta cgttcttcct tgaagatctg gatgtagaca ggggatccca
     7381 tcaactgctg cttatactct ttgctcacag gcgtggtaga gctactgctg cccagcaaac
     7441 cggcaaatga aacgcacggg atcaacaaca tcgcaagaat taatgcgatt ttacgcatac
     7501 tgcttattcc ttgataaaac ggttacacac gccaggacgg caaaatggat cccaaatcgg
     7561 aatagtctgg atttggaagg ctcacattat caccaaaaga gttttacgca agcctgtcgg
     7621 cgcagggttt acaaatttca tcggaagcgg gctttaccca aagagcgccg cgtgagttcc
     7681 agttctctca aatcgtaaaa gtttatcggt aagtttgtaa atcaggatcc agtccggttc
     7741 gacatgagca tcgcgataac ctttccatga accttgcagc gggtggtctt tataaacagc
     7801 tggaagcggt aaagtattat tgataagaag cgtcataaga tatttcaatt tattcatatc
     7861 cttatgacgc ttttgtgcaa gttttacatc ctttgaatat tgtcccgagt attcaatatc
     7921 cctttgaatc atatttaaat tcctaattta tcaaataaat catcggcgtc tttggcctta
     7981 tgaacatcaa tgccagcttc gctgtttttg attgattgaa tggttaattg attaggctcg
     8041 cgtaaatcaa acggcaatgc cttttcacgc gcgacctttg tgagggttat gcgaaccagg
     8101 tcagagatgg tcagccccat cccggccagt acgtccgctg cctgattctt cagatcttca
     8161 tcgattcggg cgcgaacaaa cgcgttagca gccattgggg tatctcctgt gctgtatatt
     8221 tattcagctt gaattgtagc tcaaatgagc aacagcgaca atccatgagt aatttaataa
     8281 acggatgttt ttacataatt aactgaaata tatatgttaa ttttataata atggtttatt
     8341 aagtttgttc agaaacgatc cgggatacac tgcaacatta aagcatgacc agccattatt
     8401 gagtatgtcc ttgccgtcga ttccatcctt tgtattgtcg ggattactgt tgatttgttt
     8461 gccgttttct tcatttgcca gcgccaccac atcacatatc tctttcagct acgccgcccg
     8521 ccagcggatg caaaaccgtg cgcgtttatt aaaacagtac caaactcatc tgaaaaagca
     8581 ggccagctat attgtggaag gcaatgccga aagcaaaagg gcgctacgcc agcacaaccg
     8641 ggagcagata aaacagcatc cagaatggtt tcctgctccg ctcaaggcga gtgacagacg
     8701 ctggcaggcg ctggcggaaa acaaccactt tttaagcagc gaccatctgc ataacattac
     8761 cgaagtggcg attcaccgcc tggagcagca gcttggcaag ccttacgtct ggggcggtac
     8821 gcggcctgat aaaggctttg actgtagcgg gttggttttt tatgcctaca acaagatcct
     8881 tgaggctaag ctcccgcgca cggccaatga gatgtaccac tatcgccggg caacgattgt
     8941 ggcgaacaac gacctgcgcc ggggagattt gctgtttttc catatccaca gccgcgagat
     9001 agccgatcat atgggcgtgt atttgggcga tgggcaattt atcgagtcgc cacgtaccgg
     9061 cgaaaccatt cggataagcc gattagccga acctttctgg caggaccatt ttttgggcgc
     9121 gcgcaggatt ttgacggaag agacgatttt gtaggacgga taaggcgttt acgccgcatc
     9181 cggcagttgt acgcaggtgc ctgatgcgac gctggcgcgt cttatcatgc ctacgagccc
     9241 gcgaatattt gcgagccgct ttcccgatat aaaacaacct cattgccaac ctttcctttt
     9301 cttcttaccg ttgagaaaaa ggagtcgcca tgtctgaata tcgtcgttat tacatcaagg
     9361 ggggaacatg gtttttcacg gtgaatttac gaaatcgtcg aagccaactt ttgaccaccc
     9421 agtaccagat gctccgtcac gccattatta aagttaagcg agacaggcct tttgaaatca
     9481 acgcctgggt cgttttgcca gagcatatgc actgtatctg gacattacct gaaggcgatg
     9541 atgatttttc ctcgcgctgg cgggaaatta aaaagcaatt tacccatgct tgtggattga
     9601 aaaatatctg gcaaccacgt ttttgggagc acgccatccg caataccaaa gattataggc
     9661 atcatgttga ttatatttat ataaatccag taaagcatgg ttgggtaaag caagtgagtg
     9721 attggccatt ctcaacgttc catcgcgatg tcgcgcgagg gttatatccc atcgattggg
     9781 cgggggacgt aacggatttt agtgccgggg agcgtatcat ttcataattg tgcgcagatg
     9841 cctgatgcga cgctagcgcg tcttatcatg cctacaaact tgtgccggat cggtaggccg
     9901 gataaggcgt ttatgccgca tccggcagtt atgcgcagat gcctgatgcg acgctggcgc
     9961 gtcttatcat gcctacaaac ttgtgcctga acggtaggac ggataaggcg ttcacgccgc
    10021 atccggcagt tgtgcaccaa tgctggatac ttacatcaac gcccccataa tcttcaactc
    10081 cagctcatcc ggcacttcgt tatacgacag cacatgcagc cccggcgcaa acaaccttgc
    10141 ataacgcgcc agcaaagggc gcagctgcgg tggcaccagc agcaccgggt ctttccccgc
    10201 cgctttcatc tgctctttca cctgtggcat cgtactctgg aactggttga gcatattcgg
    10261 atcgaccggc acgctgtcga gcatcacttt cccgccctgt tgcgcctgat tcaccacgtt
    10321 ggtcagcaga ttttccagct cattattcag cgtatacacc gtcagctcct gcttgcgaac
    10381 gaacggatgg gtaatgctgc gccgcaatgc caggcgcaca tcggccgcca gcagaatatg
    10441 atctttcgtc accgtgctac tggcgaccag cacggtggcg atggtgacga tatcgcgcag
    10501 ggaaacgcct tcggtcagca gcgcccggta cactttcagc aactggctgt aattgagcgc
    10561 cgcgctcaaa tcttccgcca gacgcggtgc cgtcgacgat aaacggttat gcaactgcgt
    10621 aatatcatca tagttaaaca aatcaggaat atagctgcgc acaatcttat ttacatgggt
    10681 agcgatcacg ctggcgctgt cgatcacctg ataccccata ttcagcgcct tcgctttctg
    10741 cgccgcctgg atccaggtga ccggcatccc gtacgccggg tcgttcccct gcacgccgtc
    10801 aatctcgccg taggtttcgc tggagggcag ggccatcagt ttatccgccg gaatatccgc
    10861 ttcatcagcc tttatgccgt tgatgaaaat ggcgtactga ctgggcttaa ggcggaagtt
    10921 ttcccgaatg cggatctccg gcagcagcac gccgttgccg tcagaaatca cctgccgcac
    10981 gccgcgaatc cgctgggtga gcgggttacc ctgtgctttg tccaccagcg ccaccagttt
    11041 gtaaccgagg cttaaactga taggctcgat cagcggaatg gtttcccaac tgacctgctg
    11101 ctcgctggtt tcggtgatgg tgcgggtcag cgtttcgagg cttttctctt ccgcctccgc
    11161 cgccagcggc tgtttgctca tccgccagcc ggtaaaacca agcagggcgc tgaacagcaa
    11221 aaacggcagg tgcggcattc ccggtaccac cgccagcacg aacataatcc cggtggcggt
    11281 gtagagcacc gacgggcttg ccagcagctg gttacgcacg tcatgggcga tatcgccgtt
    11341 gtcgctgacg cgggtgacga taatcgccgc cgcggtggag agcagcaggg aagggatctg
    11401 cgccaccagg ccgtcgccga tggtcatcag cacatactgc tggaaggcag catcggcgct
    11461 caggttgtat ttgaagatcc cgatacagac gccgccgatc aggttgatcg ccagaatcat
    11521 catcccggcg atggcgtccc cgcgcacaaa cttcgatgcc ccgtccatcg cgccgtagaa
    11581 atcggcctcg ctggcaacat ctttacgccg ggtttgcgcc tgcgcctggt tgatcaatcc
    11641 ggcgttaaga tcggcgtcaa tcgccatctg tttgccgggc atcgcgtcta aggtaaagcg
    11701 ggcagaaacc tcggaaatac gctcggcccc tttggtgacg acaataaagt tgattgtcaa
    11761 cagcgtcagt aaatccgagc gtgaaagcat tatcgccgcg ctgcacgggc agtcgatttt
    11821 taacggtggt gggctgtcgc cgttaaataa aatcagcccg tctcatccgc caaaacctgc
    11881 caccgtggcg gtgccggaag agacggagaa aaaagcgcgt gatgtgaatg agaaaacggc
    11941 gctgctgaag aagaaatccg ccaccgagct tggtgagctg gcaaccagta tcaacaccat
    12001 tgcccgtgat gcgcatatgg aagcgaatct ggagatggag attgttcccc agggattacg
    12061 cgtgctgatt aaagacgacc agaaccgcaa tatgtttgaa cgcggcagcg cgaagattat
    12121 gccgttcttt aaaacgctgc tggtggagct cgcgccagtg ttcgactcgc tcgataataa
    12181 aattattatt accgggcata ccgatgcgat ggcctacaaa aacaatatct acaacaactg
    12241 gaacctttcg ggtgaccgcg cgctttcggc tcgtcgggtg ctggaagagg ccggaatgcc
    12301 ggaagataaa gtgatgcagg taagcgcaat ggcggaccag atgctgctgg attccaaaaa
    12361 tccgcaaagc gcgggcaacc ggcgcattga gattatggtg ctgaccaaaa gtgcgtccga
    12421 tacgctgtat caatactttg gtcagcatgg ggataaagtg gtgcagccgc tggtgcaaaa
    12481 gctggataag cagcaggtgc tttcgcagcg aacgcgttaa atgctgaatc tttacgcatt
    12541 tctcaaaccc tgaaatcact gtatacttta ccagtgttga gaggtgagca atgcgtaaaa
    12601 tcattcatgt ggatatggac tgctttttcg ccgcagtgga gatgcgcgac aatcccgccc
    12661 tgcgcgatat ccctattgct attggcggca gccgcgaacg tcggggggtg atcagcaccg
    12721 ccaattatcc cgcgcgtaaa tttggcgtac gtagcgctat gccgacaggg atggcgctca
    12781 aattatgccc acatctcacc ttgcttccgg ggcgctttga cgcctacaaa gaagcctcaa
    12841 atcatatccg tgaaatcttc tcgcgctaca cctcgcgcat tgaaccgttg tcactggatg
    12901 aggcttatct cgatgtcacc gatagcgtcc attgccacgg ttctgcgacc ctcatcgccc
    12961 aggaaatccg ccagacaatc ttcaacgagc tgcaactgac ggcgtctgcg ggcgtggcac
    13021 cagtaaagtt tctcgccaaa atcgcctccg acatgaataa acccaacggc cagtttgtga
    13081 ttacgccggc agaagttccg gcatttttac aaaccttacc gctggcaaaa atccccggcg
    13141 tcggcaaagt ctcagcggca aaactggaag cgatggggct gcggacctgc ggtgatgtac
    13201 aaaagtgtga tctggtgatg ctgcttaaac gctttggcaa atttggccgc attttgtggg
    13261 agcgtagtca ggggattgac gaacgcgatg ttaacagcga acggttgcga aaatccgtcg
    13321 gcgtggaacg cacgatggcg gaagatattc atcactggtc tgaatgtgaa gcgattatcg
    13381 agcggctgta tccggaactt gaacgccgtc tggcaaaggt aaaacctgat ttactgattg
    13441 ctcgccaggg ggtgaaatta aagttcgacg attttcagca aaccacccag gagcacgtct
    13501 ggccgcggct gaataaagct gatctaatcg ccaccgcgcg taaaacctgg gatgaacgcc
    13561 gcggcgggcg cggtgtgcgt ctggtggggc tgcatgtgac gttgcttgac ccgcaaatgg
    13621 aaagacaact ggtgctggga ttatgatgta tactattatg tatattctgg tgtgcattat
    13681 tatgagggta tcactgtatg catcgaattc tcgctgaaaa atcggtcaat atcactgagt
    13741 tacgtaaaaa cccagctaaa tactttattg atcaaccggt tgcggttctt tctaataatc
    13801 gccccgcagg atatctctta agtgccagcg cattcgaagc gttaatggac atgcttgctg
    13861 aacaagagga gaaaaagccc ataaaggcgc gcttccgtcc aagtgctgca agattagagg
    13921 aaattacacg ccgcgctgaa caatatctta atgatatgac ggatgatgat ttcaatgact
    13981 ttaaggaata aggatgcggg tattcaaaac aaaacttatt cgcctgcaac ttacagcaga
    14041 ggaacttgat gcgttaacgg cggattttat ttcctataag cgtgacggtg ttttgccaga
    14101 tatatttggt cgcgatgcac tctacgacga ctcctttacc tggccattaa tcaaatttga
    14161 gcgagttgct catattcatc tggcaaatga gaataatcca tttccgccac agttgcgcca
    14221 attcagcaga acgaatgacg aagcgcattt ggtatattgt cagggggcgt ttgatgagca
    14281 agcatggttg ctcattgcca ttctgaaacc tgaacctcat aaactggctc gagataacaa
    14341 ccaaatgcat aaaattggga aaatggcaga agcgtttcgc atgcgttttt gaatttatat
    14401 tatgaataac atacaaataa gaaactatca gcctggcgat tttcagcaac tatgcgctat
    14461 tttcattaga gcggttacga tgaccgccag tcagcattat tcaccacaac aaatttccgc
    14521 ctgggcgcag attgacgaat ctcgctggaa ggagaaactc gcgaaatcac aagtgtgggt
    14581 tgcgatcatt aatgcacaac cggttggttt tatttcccgc attgaacatt atatcgatat
    14641 gttatttgtt gaccctgaat acacccgccg tggggttgcc agcgctttgt taaaaccttt
    14701 gattaagtct gaatccgaac ttacggtgga cgcaagcata accgcaaaac ccttttttga
    14761 acgttatggt tttcagacag ttaagcagca gcgcgttgaa tgccggggag cgtggtttac
    14821 taatttttat atgcgatata aaccgcaaca ttaaatccag cttgcaatga aaataacgcc
    14881 cgcctggtat gtgcgcgttt tctgattcca caaactgcaa ggaggtaaat catgacaaat
    14941 cctttatcaa tgactctttg cagacctttc caggattaat tctttttttc ttgccctgga
    15001 ttcgtctgcc atttcctgat ttttatattt atatactcta aataattcga gttgcaggaa
    15061 ggcgacaagc gagtgaatcg ccaggagctt acataagtaa gtgactgggg tgaacgaacg
    15121 cagtcgcagt acatgcaact tgaagtatga cgagtataaa tggaatggta catgggcaaa
    15181 tatattcgtc ccttatccga tgcggtattt accatcgcat ctgatgacct gtggatcgag
    15241 agtttagcga tccaacaatt acacaccacg gcaaatttac ccaacatgca gcgcgtagtg
    15301 gggatgccag atttacaccc cggacgcggc tacccgattg gcgcagcgtt cttctctgtt
    15361 ggtcgttttt acccggcaag acgtcgcggt aacggtgctg gaaacagaaa cgggccgcta
    15421 ctctgacaca ctgcgttcgg cgctggtttc tctcgatggc gataacgcat gggcattaag
    15481 cgaaagctgg tgtggcacta ttcagtggat ttgtccgagt ccgtatcggc ctcatcatgg
    15541 gcgcaaaaac tggtttctgg gcattgggcg ttttaccgct gatgagcagg aacaatcgga
    15601 tgcaatccgt tatgagacgc tgcgttcgtc ggggccgggc ggtcaacatg tcaataaaac
    15661 cgactcggcg gtacgcgcca cgcatttggc atccggtatt agcgtgaagg ttcagtcaga
    15721 gcgtagtcag catgctaaca agcggctggc acgattgctg attgcctgga agctggagca
    15781 acagcaacag gaaaatagcg cggcgctgaa atcgcagcgg cgaatgttcc atcaccagat
    15841 tgaacgtggc aacccgcgac ggacatttac agggatggct tttatcgaag gataatgaag
    15901 gatgaaactg ccggaaggcg attaaacgcc atccggcagc aaatcaaata attacttcgc
    15961 cggaatttct ttcagcagtt cagtcagcag tgtccagtaa tgacctacgc tttcgatgtg
    16021 aacttgctca tccggagagt gtggaccggt gatagttggc ccgatagaaa ccatgtccat
    16081 ttccggatac ggttttttga acagaccaca ttccaggccc gcgtggataa tctggatgtt
    16141 cggcgtcttg ttgaacaggc gctgataggt ttcacgtacc agatgcatca ccggagaatt
    16201 agcgtccggc tgccagccag gatatgcgcc tttcgcttcg gttttcgcgc cagccagttt
    16261 acccagcgaa tccagcatgc tcaccacgta gtctttaccg ctgtcgatca gtgaacggat
    16321 caggcagtga atttctacgt tattgtcagt catggtcacc acaccgacgt tcagggaggt
    16381 ttcaaccaca cctttggcta catcggagtt acgaatcaca ccgttcgggg tggcgttcag
    16441 cagacgaata aaggtatcgc gagatttcgc aatcagggca gctttatcgt tcgctacaga
    16501 gtccagcaac aaggccagat ttttctcttt ttctgccagc tcgtttttca ggatctcctg
    16561 ataggtattc accagagatt tcaggacgtc gactttatca gctgcgacag caatggtcgc
    16621 aaaggcttca cgcgggatgg cgttacgcag tgtgccgccg ttgaaatcga taaggcgcag
    16681 atccagttct tccgcatgac ccgccaggaa gcgcaccagc agtttgttgg cattacccag
    16741 cccaacgtgg atttccccgc cggagtgacc gcctttcaga ccttttaagg ttaacttgaa
    16801 ggtttcaaaa ccagctggaa ccgcttcacg atctaaatgc aggttggagg tgaagtcgat
    16861 accccccgca caacccatgt agatttcacc ttcttcttcg gagtcggtgt taatcagaat
    16921 atcagcctgc aaccagttgc cctgtaagcc gaacgcaccg tccataccgg cttcttcggt
    16981 catggtcagc agcacttcca gcgggccgtg aaccacgttt tcgtcagcca gaaccgccag
    17041 cgcagaggcc ataccaatgc cgttatccgc acccagcgtg gtgccgcgcg ctttaaccca
    17101 ttcgccatca atataaggct ggataggatc tttcgtgaag tcatgcacgg tgtcgttatt
    17161 tttctgcggc accatatcga ggtgggcctg taagacgacc ggtttacgat tttccatacc
    17221 tgcggtagca ggtttacgaa tcaggatatt acctacctga tcgcgttcga catggaaacc
    17281 tttctctttt gcccaaccaa caatgtattc agcgagttgc tcttcatgat aggacgggtg
    17341 aggaatagaa cagattttgg caaaaatatc ccacagcggc tgtggagata attgagacag
    17401 ttcagacacg ttaagtctcc ttgtcgatca cccgcaaaac agtattgcag gtcacagggt
    17461 tagcagaaaa tgttgtcaac acaagacagg cttgcgagat atgtttgaga ataccacttt
    17521 atcccgcgtc agggagaggc agtgcgtaaa aagacgcgga ctcatgtgaa atactggttt
    17581 ttagtgcgcc agatctctat aatctcgcgc aacctatttt cccctcgaac actttttaag
    17641 ccgtagataa acaggctggg acacttcaca tgagcgaaaa atacatcgtc acctgggaca
    17701 tgttgcagat ccatgcacgt aaactcgcaa gccgactgat gccttctgaa caatggaaag
    17761 gcattattgc cgtaagccgt ggcggtctgg taccgggtgc gttactggcg cgtgaactgg
    17821 gtattcgtca tgtcgatacc gtttgtattt ccagctacga tcacgacaac cagcgcgagc
    17881 ttaaagtgct gaaacgcgca gaaggcgatg gcgaaggctt catcgttatt gatgacctgg
    17941 tggataccgg tggtactgcg gttgcgattc gtgaaatgta tccaaaagcg cactttgtca
    18001 ccatcttcgc aaaaccggct ggtcgtccgc tggttgatga ctatgttgtt gatatcccgc
    18061 aagatacctg gattgaacag ccgtgggata tgggcgtcgt attcgtcccg ccaatctccg
    18121 gtcgctaatc ttttcaacgc ctggcactgc cgggcgttgt tctttttaac ttcaggcggg
    18181 ttacaatagt ttccagtaag tattctggag gctgcatcca tgacacaggc aaacctgagc
    18241 gaaaccctgt tcaaaccccg ctttaaacat cctgaaacct cgacgctagt ccgccgcttt
    18301 aatcacggcg cacaaccgcc tgtgcagtcg gcccttgatg gtaaaaccat ccctcactgg
    18361 tatcgcatga ttaaccgtct gatgtggatc tggcgcggca ttgacccacg cgaaatcctc
    18421 gacgtccagg cacgtattgt gatgagcgat gccgaacgta ccgacgatga tttatacgat
    18481 acggtgattg gctaccgtgg cggcaactgg atttatgagt gggccaccca ggcgatggtg
    18541 tggcaacaaa aagcctgtgc ggaagacgat ccgcaactca gtggtcgtca ctggctgcat
    18601 gcggctacgt tgtacaacat tgccgcctat cctcatctga aaggagatga cctggccgag
    18661 caagcgcagg ctttgtcaaa ccgcgcctat gaagaggccg ctcagcgtct accgggcacg
    18721 atgcggcaga tggagtttac cgtacccggc ggtgcgccca tcaccggctt tttgcatatg
    18781 ccgaaaggcg atggcccgtt cccgacggta ttaatgtgtg gtggtctgga tgcgatgcag
    18841 acggactatt acagcctgta tgaacgttat tttgcgccgc gcggcattgc gatgctgact
    18901 attgatatgc cgtcggtggg cttttcttca aaatggaagc tcacccagga ctccagcctg
    18961 ttgcatcagc acgtcttaaa ggcgctgcct aacgtaccgt gggtggatca cactcgcgtc
    19021 gcggcctttg gtttccgttt cggcgctaac gttgccgtgc gtctggcata ccttgaatcg
    19081 ccgcgtctga aagcggttgc ctgtcttggt ccggtagttc ataccctgtt gagtgatttt
    19141 aagtgccagc aacaggtgcc ggaaatgtat cttgacgttc tggccagtcg tttggggatg
    19201 catgatgctt ccgatgaagc gttgcgcgtg gagctgaatc gctattcatt aaaagtgcaa
    19261 ggattgctgg gacgtcgctg cccaacgcca atgttatcag gctactggaa gaacgatccg
    19321 ttcagcccgg aagaggactc acgcttaatc acctcatcat ctgctgacgg taaattatta
    19381 gagatcccat ttaacccggt gtatcggaat tttgacaaag gtcttcagga aatcaccgac
    19441 tggatcgaaa aacgcttgtg ttaaaaattt gctaaatttt gccaatttgg taaaacagtt
    19501 gcatcacaac aggagatagc aatgacgtta ccgagtggac acccgaagag cagattgatc
    19561 aaaaaattta ccgcactagg cccgtatatt cgtgaaggta agtgcgaaga taatcgattc
    19621 tttttcgatt gtctggctgt atgcgtcaac gtgaaaccgg caccggaagt gcgtgaattc
    19681 tggggctggt ggatggagct ggaagcgcag gaatcccgtt ttacctacag ttaccagttt
    19741 ggtctgttcg ataaagcagg cgactggaag agtgttccgg taaaagacac tgaagtggtt
    19801 gaacgactgg agcacaccct gcgtgagttt cacgagaagc tgcgtgaact gctgacgacg
    19861 ctgaatctga agctggaacc ggcggatgat tttcgtgacg agccggtgaa gttaacggcg
    19921 tgagtgaaat gtgccggatg catcacatcc ggcaatattc attaaaactg atacgtcatg
    19981 ccaaccgcga caatatcatc attattaata ttcaatttgt tatcgctatc cagttggttg
    20041 attttataat caacaaacgc tgacatattt ttgttgaaat aatacgtagc accgacgtcg
    20101 atataattga ccagatcttc atcaccgata ccttcaatat ctttcccttt cgataagaca
    20161 taacccagcg atggacgcag accaaagtca aactggtatt gagcgaccgc ttcaaagttc
    20221 tgtgtcttat tggcaaagcc gccagttatt ggcgtcattt tgcgtgtttc agaatagaaa
    20281 gttgccagat aaatattatt ggcatcgtat ttcagacctg ttgcccatgc ttctgcacgc
    20341 ttgcctgtgc cacggctttg caggttctgc tcgttggtgc gatctgagtt ggtataggcc
    20401 ccactaatgg agaaatcgct gccgccaaag tcatatgtca atgacgtgcc gaagccatcg
    20461 ccgttttgct ttttaacgtc gcggttttcg tttttccctt gatattgcag ggttaagttc
    20521 aggccatcga taacgccgaa gaagtcggtg ttccgatacg tcgccagacc gctggcgcgt
    20581 ttggtcataa agttgtcggt ctgcgccgag gaatcgccac caaattccgg gaacatatcg
    20641 gtccaggctt ccacgtcata caacgccccc aggttacgac cataatcgaa agaacccaaa
    20701 tctttatatt tcaacccggc aaaagcgaga cgcgtttttt gctgtgcagt atcactctct
    20761 gctttattac cggcaaactc tgcttcccaa cgaccataac cagtcagttg atcgttaatt
    20821 tgtgtttcgc ctttaaaacc aaaacggata taactctggt cgccatcttt actggcgtta
    20881 tcactcatat aatgcatggc tttaactttg ccatagacat ccagtttatt accgtcttta
    20941 ttatatattt ctgcagcctg tacagatgca gatgccacaa tgcccatcac cactaatgcc
    21001 agagtgctct ttttcatttt cattcctgat tttaattaac gcgcgaatat tcagcgggag
    21061 agtcccgttg aaaacaggaa agtttttaac ctgagattgt taaagatata ttacagatta
    21121 ataatattct taaaatgtgg taatttatta aatctgtaat aaaagcgtaa acaactgccg
    21181 ctaggcttgc tgatcccgcg caacaaaacg ccatgctttg ctcgcagatg gttggcaacc
    21241 gacgacagtc ctgctaaaac gttcgtttga tatcattttt cctaaaattg aatggcagag
    21301 aatcatgagt gacagccaga cgctggtggt aaaactcggc accagtgtgc taacaggcgg
    21361 atcgcgccgt ctgaaccgtg cccatatcgt tgaacttgtt cgccagtgcg cgcagttaca
    21421 tgccgccggg catcggattg ttattgtgac gtcgggcgcg atcgccgccg gacgtgagca
    21481 cctgggttac ccggaactgc cagcgaccat cgcctcgaaa caactgctgg cggcggtagg
    21541 gcagagtcga ctgattcaac tgtgggaaca gctgttttcg atttatggca ttcacgtcgg
    21601 gcaaatgctg ctgacccgtg ctgatatgga agaccgtgaa cgcttcctga acgcccgcga
    21661 caccctgcga gcgttgctcg ataacaatat cgttccggta atcaatgaga acgatgctgt
    21721 cgctacggca gagattaagg tcggcgataa cgataacctt tctgcgctgg cggcgattct
    21781 tgcgggtgcc gataaactgt tgctgctgac cgatcaaaaa ggtttgtata ccgctgaccc
    21841 gcgcagcaat ccgcaggcag aactgattaa agatgtttac ggcattgatg acgcactgcg
    21901 cgcgattgcc ggtgacagcg tttcaggcct cggaactggc ggcatgagta ccaaattgca
    21961 ggccgctgac gtggcttgcc gtgcgggtat cgacaccatt attgccgcgg gcagcaagcc
    22021 gggcgttatt ggtgatgtga tggaaggcat ttccgtcggt acgctgttcc atgcccaggc
    22081 gactccgctt gaaaaccgta aacgctggat tttcggtgcg ccgccggcgg gtgaaatcac
    22141 ggtagatgaa ggggcaactg ccgccattct ggaacgcggc agctccctgt tgccgaaagg
    22201 cattaaaagc gtgactggca atttctcgcg tggtgaagtc atccgcattt gcaacctcga
    22261 aggccgcgat atcgcccacg gcgtcagtcg ttacaacagc gatgcattac gccgtattgc
    22321 cggacaccac tcgcaagaaa ttgatgcaat actgggatat gaatacggcc cggttgccgt
    22381 tcaccgtgat gacatgatta cccgttaagg agcaggctga tgctggaaca aatgggcatt
    22441 gccgcgaagc aagcctcgta taaattagcg caactctcca gccgcgaaaa aaatcgcgtg
    22501 ctggaaaaaa tcgccgatga actggaagca caaagcgaaa tcatcctcaa cgctaacgcc
    22561 caggatgttg ctgacgcgcg agccaatggc cttagcgaag cgatgcttga ccgtctggca
    22621 ctgacgcccg cacggctgaa aggcattgcc gacgatgtac gtcaggtgtg caacctcgcc
    22681 gatccggtgg ggcaggtaat cgatggcggc gtactggaca gcggcctgcg tcttgagcgt
    22741 cgtcgcgtac cgctgggggt tattggcgtg atttatgaag cgcgcccgaa cgtgacggtt
    22801 gatgtcgctt cgctgtgcct gaaaaccggt aatgcggtga tcctgcgcgg tggcaaagaa
    22861 acgtgtcgca ctaacgctgc aacggtggcg gtgattcagg acgccctgaa atcctgcggc
    22921 ttaccggcgg gtgccgtgca ggcgattgat aatcctgacc gtgcgctggt cagtgaaatg
    22981 ctgcgtatgg ataaatacat cgacatgctg atcccgcgtg gtggcgctgg tttgcataaa
    23041 ctgtgccgtg aacagtcgac aatcccggtg atcacaggtg gtataggcgt atgccatatt
    23101 tacgttgatg aaagtgtaga gatcgctgaa gcattaaaag tgatcgtcaa cgcgaaaact
    23161 cagcgtccga gcacatgtaa tacggttgaa acgttgctgg tgaataaaaa catcgccgat
    23221 agcttcctgc ccgcattaag caaacaaatg gcggaaagcg gcgtgacatt acacgcagat
    23281 gcagctgcac tggcgcagtt gcaggcaggc cctgcgaagg tggttgctgt taaagccgaa
    23341 gagtatgacg atgagtttct gtcattagat ttgaacgtca aaatcgtcag cgatcttgac
    23401 gatgccatcg cccatattcg tgaacacggc acacaacact ccgatgcgat cctgacccgc
    23461 gatatgcgca acgcccagcg ttttgttaac gaagtggatt cgtccgctgt ttacgttaac
    23521 gcctctacgc gttttaccga cggcggccag tttggtctgg gtgcggaagt ggcggtaagc
    23581 acacaaaaac tccacgcgcg tggcccaatg gggctggaag cactgaccac ttacaagtgg
    23641 atcggcattg gtgattacac cattcgtgcg taaataaaac cgggtgatgc aaaagtagcc
    23701 atttgattca caaggccatt gacgcatcgc ccggttagtt ttaaccttgc ccaccgtgat
    23761 tcacgttcgt gaacatgtcc tttcagggcc gatatagctc agttggtaga gcagcgcatt
    23821 cgtaatgcga aggtcgtagg ttcgactcct attatcggca ccattaaaat caataagtta
    23881 cacatcatta gtaccttcct tattttttga ctgggacaaa tttgggaccg atgggttcag
    23941 gatcgagtct atttgccgtg cgtgttcggt aaggtgatta ggtgcaaggt gagcatatcg
    24001 acgaaccatt tcgatagact cccagcctcc catttcctgt aacactgaca acgggactcc
    24061 gacttgaacc agccaacttg cccaggtgtg tctcaagtcg tgaaatctga aatcatcaat
    24121 accagcccgt ctcagcgccg ctttccaggc tgtgtttgcg tcataccgca tcttccttac
    24181 tgttggcgct ttcgttccgt ctggtttggt acagctttcc ttgtacacaa atacccaacg
    24241 gtgatgattc ccgatttgtt ttttcaatac gcgacatgca gtatcattca gcgcaacgcc
    24301 aattgcgcgg tttgatttac tctcttccgg gtttatccat gccacccggc gctgcatatc
    24361 tatttgttgc cattcaaggt tgatgatgtt cgagcgtctt aagcctgttg ccagtgcaaa
    24421 ttcaacaaca gactttaatg gctccggaca ttcatcaatc agcctttgtg cttcatgggg
    24481 ctccagccag cggatccgtt tattctttgg ttgaggcact ttaataattg gtgccttatc
    24541 cagcattttc cattcacgct ctgcggctct tagtagggcc tttataaatg aaagatgcgt
    24601 agccttcgtt gcaacggacg ctggttttgg cgtgtattct ggaacaggtt tccctttttt
    24661 tctgcatgct tctgccctga gtttccagtt ttcctcatga cgccggttcg tcattttctg
    24721 cattgctgaa taaatttttg attcagtaat gtctcttagt tgcattcctg cgaaatgttg
    24781 aagccagaat ccgatccggc ttttgtcatc gtccagtgat tttttatgtg ctttctcttc
    24841 aagccacctg acacacgctt cctcgaacgt tatatcaggt atttcaccaa gtttgctgac
    24901 ccgccatgct tcagccttta gcttgtcatg gagttctgtc gcctgccttt tgtcctttgt
    24961 tccaagagac tgtttaaatc ttttaccgtt cggcaatgtg aaactggcgt accatatttc
    25021 acctctgcgg aagagtgaca ttttctttcc tctgttatgc catcacccgc gctcacctgg
    25081 acagtatgca gcggagactg aagagccgca atgcaggctt gtcgtgttgt gaggtaagga
    25141 gatttattct tagtgggatc tttgcgtgtt gcctgaagac gccctgtgcg tatccagtta
    25201 atggcagtcg gtctggatat cttgagaaaa tgacaggcct catcgagtgt gaggctgtat
    25261 ggctccatta tttcacctct tgctgtgaca ttgttgaaaa atggatacca gctcgttgct
    25321 gccagacgat ccaaccgaga gtcatatccc atgccatgta ttcgttattg ccgttttttg
    25381 ctctccgacg atctactaag tcaccgaaac gcttttccat gaataattca taagcttcgc
    25441 gttcatctgg ttctacttcc agagatagga gtgcgatttc ataagcacgg cgctcaatat
    25501 cgtctcgcac gtcaaggctg ctgatacgct ctttaatttc tttaatcagt tctttgtcgg
    25561 taaaagtggt cattatgctc cagcctccgg tgcttttggc attactgccc agtgagtgat
    25621 attgacgttt tcaaggtccc cgacctgaaa tgtccactgc cattctccgg tttctttttg
    25681 tccccaggtg taccagagag aacgccagcc aattagccag ccttctccgt tagcatcgaa
    25741 taacaaaaca ctttcatttg ctggtggcag ttcagttgac actggtatta ctttgttttc
    25801 ctgtgctgca catttagctt caagcgcatc gaatttacgc actaggtatt cagcatctgt
    25861 ttcatttact ttcagatctc gcggtacaca tctcccacga agaaaccctt ccatttcgaa
    25921 aacattcatg cgcatttgcg taactccgat aactcgttaa agcgttccat aaacatcccg
    25981 taggcatggc ccggtgccag tggaatcacg ttgaacatct ctgttgccgg gataccttcc
    26041 agtacaggcc agaaagagcc atcatcaagc ccgagatcgc ggcgttcggt tgccagcatg
    26101 atgagatcgg catatttcac gggcgtactc ataactgggg gtaacccgta tttctcacgg
    26161 attacggcgt ctattttttc ttccatttgt ttatagtcag gaagaaggcg tttcagtggt
    26221 gcgggaatgt cctggcaata cgcttctgtt gcatcatgca ttaacgcttc aaaagcaaat
    26281 tcctgcggca ccagctggct gcaaagaacc gcatgttggg cgacgctgta gaagtgcgaa
    26341 agatgaccgg caaagcgaca gatatttgaa agggaaaccg cgatatcgtt aatatcgatg
    26401 tcgtctttat ttatcctgtc ataataaaaa tgcttcccgg aaaaagtttt aataaatgac
    26461 attttgttct ccacgtatat gcgctgcacc gcgctgaatt ctggtaaaaa gaatccctca
    26521 ccatccggcg attattgagt aaattacgtt tccataaatg cccccgcagg ggcatttgca
    26581 gtaatgaaat caggcggtga aagtaccaat aaaggtttct actttgctgt ccttgaattt
    26641 ctcaacaagc agatcacgaa attcgttagc catttcttcc tgcaccgcct ccagctgaat
    26701 aatgcgcaga accagtacag gacgatcgcc agtgataata ctgaggcgta atttaaacgg
    26761 acgttctttc agaccttcaa acggaacgca tttaaattca aatgccactg gcataatgtc
    26821 tttggtcttc gcttcgacag actccatcag ggagcgtttg ccgctgaagt cattatcttc
    26881 aaaatcagcg gtctggtttg cttcaatcgt gattttacgg acagccgcag ccgcttttgt
    26941 tgcctgaata gcgtcaccat tagcatcaaa gcccacaaga tagtcggccc agtcttcaat
    27001 ccattctgct agtgacttct gggagttacg ctcgccgtta acagacaaca gagcagagaa
    27061 cggtgctgtc tttttcagtt tgagtgtggc ggtgttatct gcgtgacctg gttcatcaat
    27121 agtacctagg ttaagcacac tgacggcacg catattatca gcatcgataa agcagcgggt
    27181 gccttcatct gcaagatctt tagaataacg ggtaaaatca tcgatgctgg cagtggaaag
    27241 cgtaccacgg aaacggaagc gatttaaatt aaatttttcc agatcatgaa tgcggaaatt
    27301 ctcaggcaat gccacagcat cggcaccaat cttactgata atttcattaa caccctgagc
    27361 agaaataagg gcatggattt gattaattgc ggttgcgtct aagttctgag acataataag
    27421 tcctcactat ataaagatat tcagtgatga gataaataat cagttaatta aaaacgatat
    27481 taacgacctg ctgcgcggag ttttccgtca ggttcaccgg caagagtcag caactgtccc
    27541 tggtcttcct gcagaatagt caggcgacca ccgcgattga catacatcgg cgtttcggtg
    27601 gtgtcttctt cggaaatttt cccgcggtta gtcgggcgaa catatgagag tttgtgtttg
    27661 attttcactc ggttctcatc aaacggttcg atttctaggt tgagcgagac cttacctttg
    27721 gttttcgtgt tcatcacacc ggaagcgact tcactgagaa ctgcgccgat tttggtttca
    27781 aatacgccgc cgtccagctc cccgataaat gcctgcacat cagtactgcg ttcgctagcc
    27841 attttgctgc tcctcatcat atcgaccctg caaggtcggt tggtttctcc acaaaacaga
    27901 gaagaacacc tgcggtggca gccgctcgga tggattgggt tatgagcccg tcgtccggtg
    27961 atgctcttct ctgttttgca aaaaaggacg gtaccagccg gaagcaaggg tacaaactgg
    28021 taccgccagg actacacaca gcataaagtt gtggtgccgg gtgcctcccg gtgcctggcg
    28081 aaggttgcac accaggcggg tgggtatcca cagaaggtcg actgtcagcc tcaaccttaa
    28141 cccgcgtgcg ctgagccgca ttcaccacaa cgctaaggat tctctctggt tgaaaatact
    28201 tagctgttat gtgcctgctt ttagccacat caggcgaggt ggacctggtt attccccaac
    28261 aacaaggatt cggttaatct ggatatcccc aacaacaata agagtattca atgtgatcgc
    28321 tgaattaacg gcagcaatga cggctattcg tgaaatcgcc cagattgcaa aactaatgaa
    28381 cgaggcaaaa actcaagctg aagtaaatgc ggctattggt gagctgaact caaagcttgc
    28441 gtctattcag cgcgaatgcg tgtctctcgt tgaactgctg ggctcttatc aagaaataaa
    28501 tgcttctctc aaagctaaaa ttgcagaatt cgaaaacttt gaggctcaga cggaaggcta
    28561 tatccttaac caacttgagt cgggtacttt tgtatactcg aaggaggtaa tcgtgaacgg
    28621 tgacagcata accatgcatc tttgcccaaa atgttttgga caaaagatag tatcgatact
    28681 tcaaccattc ccggttagcg aagatgagct ttttcataaa agcaggtgcc tccactgtga
    28741 aaataagttt ctgatgaata aaaatccgga ttacgtatcg cctccatcca ttgaggagtt
    28801 ggccagaaaa cttaacggca atctgtagat tgctactgtt gtggatatcc agattgttaa
    28861 agagctaagc gtcctgtagg gcgctttttt gttgctaacg aatcatcctg gacttcatat
    28921 gccccaggcg gctacttcgt gggcgtcctg cctgttcgtt atctttgata taaaatctaa
    28981 cttaacttag ttattatggc aagagaaaac accaaacttt tcttagttcg gtgccttagt
    29041 tagagaagag aggtcttaga gttcgtattg aactcctttg actacaccaa tgataaggca
    29101 attaccattg atagggatgt tgggataccg aggatttaat ggcactaaaa acttttgagg
    29161 gccatcgatg actaattttt ttactgtagc ttcgtttgtt ccatcaagtc gagcgatgac
    29221 tatttttcca tgacgaggtt ctgcatctgg atctacaatc actgttgcgc cttctggtat
    29281 tgttgggagg ccattagggt tagtcatgga gtcaccttta acctctaatg caaatgagtt
    29341 atcaccaatc tttaatgatg tatctaccca cttgtccact tcactaaaca cttctgctgc
    29401 cctgcactca gtaaactgcc cagcctgaac ccacgatatt acaggaactc tgcgcatgtt
    29461 tgtgacgagt ttgccttcaa actcagcacc ataaagaatg taatctattg acgtattgaa
    29521 gaacttcgct aatttcgaaa gtgcctcccc accaggggta ttgatgtctt tctcccagta
    29581 ccccacagca acgtcgctta ctccacaaaa tttacccaat tctttctggg acgttccggt
    29641 aactcttctc agagctttta tacgctgacc aaccgtttcc ataggagcac catttcttga
    29701 attgctaagt aatcttagtt tttattgacc aaagatagat ttgtaattag catctaataa
    29761 aacttagttt ggagggcgta tgacaactga cgatatcgaa agctacttcg gcagtattga
    29821 gaaagttgct gcttttttcg gcataacaac tgaagccgtt tatcagtggc gaaaccgtcc
    29881 gggccagtta attccaaaag gacgtgcagc agaagctgca tatagaactt gcggacggtt
    29941 gccatttaaa cctgagcttt atgaaaaatc taatggataa atcgattaac agaaaccaca
    30001 gaacgatgag gctaaccgtg ggtaagcatc actggaaagt agaaaaacag cctgagtggt
    30061 acgtgaaagc tgtcagaaaa actatcgcag cgttgccggg tggttacgct gaagcagctg
    30121 actggctgga tgtaacagaa aacgcattat ttaaccgcct tcgtgccgat ggcgatcaga
    30181 ttttcccgct gggatgggca atgattttgc aacgtgctgg tggaactcac ttcattgctg
    30241 acgctgtggc gcagtctgca aatggcgtct ttgtgtctct tcctgacgtc gaggatgtgg
    30301 acaacgccga tattaaccag cgcctgctgg aagtcattga acagattggc agttattcca
    30361 gacagattcg ttcggcaatc gaagacggtg tggtggaacc gcatgagaag acagcaatta
    30421 acgacgagct gtatctctca atttcgaagc tgcaggagca tgcagcactg gtctacaaaa
    30481 tcttttgcat ttcagaaagt aatgacgccc gcgagtgtgc agctccgggc gccgtggcgt
    30541 gtcgtgactg tggagaaact aacgcatgaa cagtttaaca acacactacc gtcgctcgca
    30601 actgattgcg cttcctgtac cgggtggaaa agcgaaggtg gagtattgct atgcagttaa
    30661 tgtaccaggt gacagggaaa ttgtaaccca cagctttgct gagtgggctg tgggtgattt
    30721 caaccggcag aaggagacag tcctttgcga caagttaacc gctggttcaa agatcactac
    30781 ggagtgcccg tcagagtcat tcgttgggag ccggaaacac aacgagttat ctacctccgc
    30841 gaaggctatg agcatgagtg cttcagcccg ctcgaacagt ttcgtcgtaa attcagggaa
    30901 atagaggtcg gtcatgagca ctaaattaac cggctatgta tgggatggtt gcgctgcatc
    30961 aggcatgaaa ttatccagcg tggcaattat ggcccgcctg gctgatttca gtaatgacga
    31021 aggtgtgtgc tggccatcaa ttgaaaccat tgcccgtcag attggcgcgg ggatgagtac
    31081 cgtcagaacg gctatcgcac ggctggaagc agaaggctgg ttaacgcgta aggcgcgtcg
    31141 ccagggtaac cgcaatgcgt cgaatgttta tcagcttaac gttgcgaagc ttcaggcagc
    31201 ggcattttct caactgtcag attctgaccc gtcaaaatct gacgcatcaa aatctgacac
    31261 gtcaaaattt gatgcgtcga aatctggcaa aaaagcgggt tttcacccgt cagaatctgg
    31321 cggggatccg tcagtaaaat caaaacatga tccgtcagat aaaaaacctt ctcgtccgga
    31381 cgcttcgcaa ccggacacgc agacggctga acaggatttt ttaactcgcc atcctgacgc
    31441 ggttgtattc agccctaaaa agcgccagtg gggaacgcag gatgatttga cctgcgcaca
    31501 gtggctctgg aaaaaaatca ttgccctgta cgagcaggcc gccgaatgtg acggcgaggt
    31561 ggttcgtccc aaagaaccga actggacagc atgggcaaac gaaattcgcc tgatgtgtgt
    31621 gcaggatggt cgtactcaca aacaaatctg cgagatgtac agccgcgtca gccgcgatcc
    31681 gttctggtgc cgtaacgtgc tcagcccgtc gaagttgcgg gaaaaatggg atgagctttc
    31741 cctgcgctta tcgccatccg tcagcacgca cacagaaaaa cgtgaagacc cgtacttcaa
    31801 agccagttac gacaacgtgg actacagcca gatcccggca ggattcaggg ggtgatcatg
    31861 agtcttttga atgaagttca gaaattcatt gaagcccatc cggggtgtac ttccggagac
    31921 attgcggatg cttttgcagg ttactcacgg cagcgcgttc tgcagtcagc aagcaagtta
    31981 cgtcagagtg ggcgtgtggc tcaccgttgt gaaggagata cacgcagaca tttcccacgc
    32041 ctgactgaga gagcgcagga gccggaacca caaccagttc gtgaaaccag acctgtgcgc
    32101 aatttctatg tcggcactaa cgatccccgg gtgattttgt gcctgacccg ccaggcggaa
    32161 gaactggagt ccaggggctt ataccgtcgt gctgcaacgg tgtggatggc ggcattccgt
    32221 gaaagctact cccagccaga acgaaacaat tttctggcgc gtcgtgaacg gtgtttacgg
    32281 aaaagcagta agcgggctgc atcaggtgaa gagtggtatc tgtcagggaa ttacgtgggg
    32341 gcttaatgac gacgttaact caatgccagc agcaggtgct ggatatgctg atttcttacc
    32401 agaaagaacg tggcttcccg ccaaccaatc aggaggtggc aaccatgctg ggataccgtt
    32461 cggtgaatgc agcggtggag catcttcgcg cactggagaa aaaaggcgtc atcacgataa
    32521 agcgtggcgt ggcccggggg ataacgcttc ataccgcggt gaaggacgac gacagcgagg
    32581 ctgtcgggat tatccgctca ctgcttgccg atgaggaaaa cgcaaggctg cgtgcaaccc
    32641 actggctaca tgagagaggc ctgaaagtat gaaactgatc ctgcctttcc cgcccagcgt
    32701 gaacacgtac tggcgacacc ccaacaaagg ggcgtttgct ggtaagagcc tgataagcgc
    32761 ggcggggcga aaattccaga gcgcggcgtg cgcagcaata gtgagcagtt acgtcgtctg
    32821 ccgaaaccaa cgtcggcacc tgcttcagtg gagatcgtgt tgtttcctcc ggataacagg
    32881 atccgcgatc tggacaacta taacaaggcg ctgtttgacg ccctgaccca cgcgggggtg
    32941 tgggaagacg acagtcaggt gaaaagaatg ctggtggagt ggggaccggt tatcccggaa
    33001 gggaaggtcg agatcactat cagtaagtac gagaaaacgg cgggtgcagc cgcctgatta
    33061 agaggagaaa cgaagtatga ataatctgat ggtcattgat ggtattgaag ttcgtcgtga
    33121 tgcttatgga cgttatagcc tgaacgatct gcatcgcgca gcagtagcat ctggtgcaaa
    33181 tgccagaacc aaggagccag gaaagtttct ttccagccaa caaactgttg agcttgttca
    33241 tgaattgacc aacacccaga atttgggtgt tgacccggtg agtgtgattc atgggggaaa
    33301 tgaacgggga acgtatgtct gtaaggaact ggtgtatgcc tatgcaatgt ggatcagccc
    33361 gtcattccat ctgaaggtga tccgtacttt cgatatggta accagcgcac cggaaaaatt
    33421 atccgggcag gctgctgaca agatgcaggc tggagtgatt ctgctggact ttatgcgcag
    33481 ggagttaaac ctgtctaact catctgtgct tggggcctgt cagaaactcc aggaggctgt
    33541 tggcttaccg aatctggcac cgcgttatgc cattgatgct cctgctgacg cgcctgatgg
    33601 ctcaagccgc cccacgctgt cactgagtgc actgctgaag cagtatggta tccgcctgac
    33661 ggctaatcag gcatatcacc agatggcgaa gctggggatc gtcgaacagc gcgaacgata
    33721 cagccgtaca gcgattaaca acatcaaaaa attctggtcg ctgacagcga aaggctgcat
    33781 gttcggcaag aacatcacca gtcccgcaaa tccgcgcgag acgcagccgc atttcttcga
    33841 atcccgattc cctgagctgt taaagctgct cgataccgtt cattgaggtg accgtgagag
    33901 cactactgac ccctgaaatt gccccgcgta tggggatcgt attgttcagg ccaggttcag
    33961 agctgatgcc cctgtttatg caggggcgtg tcctgctgga gcctgagccg gaacgttatt
    34021 catctttcgc cagtggtgcc gttccggcgg catcacaacc gctggcggat gatcctgccg
    34081 ttcgggccgt gttccgcaat gaggcagtga tccgtcgtgc tggtggcgtg gaatgtcttg
    34141 aaagctggtt acttcgtgaa aaaggctgcc agtggcctca ttccgactgg cacagcgaga
    34201 acatgaccac aatgcgacac gcgccgggcg caatccgtct gtgctggcac tgcgataacc
    34261 agctgcgcga tcagttcacg gaacggctgg aatcaatggc aacggataac tgtgcccgct
    34321 gggtgttgtc tgttgtgcgt cgggatctcg gttttgatga cagtcacgtt gtgacaatgc
    34381 cggaactgtg ctggtggctg attcgtaatg acctggcgga tgccttaccg gaaagtgcag
    34441 cccgtaaggc actgagatta ccaaagcctg ttgtgccgtc tgtcacccgg gaaagtgacc
    34501 ttgtgccttc ggttcctgcc accagcatca tccaggataa agcgaaaaag gtgctggcgc
    34561 tgaaagtgga tccggagtcg ccggagtctt ttatgttacg cccaaaacgt cgccgctggg
    34621 ttaatgaaaa gtacacgcgc tgggttaaga cacagccgtg tgcatgttgt ggaaagcccg
    34681 ctgatgatcc ccaccacctg ataggtcacg gtcagggtgg aatgggaaca aaagcgcatg
    34741 acctctttgt gttgcctttg tgcagaaagc atcacgacga gctgcatgcg gataccgtgg
    34801 catttgaaga gaagtatggc tctcagctgg agctgatatt tcgttttatc gatcgtgcgc
    34861 tggcaattgg cgtattggcg taagtggaga acgagcatga accttgaagc cttaccaaaa
    34921 tattactccc caaaatctcc aaaattgagc gatgacgcac cggcgacagg ctcaggtggt
    34981 ttaacgatta cggatgtgat ggctgcgcag gggatggtgc agtcgaaagc accgcttggg
    35041 tttgccttat tcctggcaaa agttggtgtt caggatcctc aatttgcgat tgaaggtctg
    35101 ctcaattacg cgatggcact ggataacccg acattgaaca aattgagcga agaaacccgg
    35161 ttacagatca tcccttacct tgtgaatttt gcctttgctg attattccag gtctgcggca
    35221 agtaaggctc gctgtgagca ttgtgctggt actggatttc ataatgtatt gcgcgaagtg
    35281 gtgaaacact ccagaagcgg ggaatctgtt atcaaggaag agtgggtgaa ggaactatgt
    35341 cagcattgtc atggtaaggg agaagtcagc acagcgtgca gagggtgtaa gggtaaaggt
    35401 cttgtcctgg atgaaaaaag gacccggctt catggcacgc ctgtttataa gatttgtggg
    35461 cgttgcaatg gaaaccggtt tagccgttta ccaaccacac tggcgcggca tcatgtccag
    35521 aagctggtac cagacctgac ggattatcag tggtacaaag gatatacaga tgtcattgat
    35581 aaactggtta caaagtgctg gcaggaagaa gcatatgcag agatacaatt gagaaatgtg
    35641 acaagataaa tggttttcgc cgaagatgac gacatgatgc ttgcattttt caaaaaatat
    35701 ggataagatt ttcccaacga tgggctttgt atgtctaccg ttgataagat ttaagaaccc
    35761 gccactgagc gggttttttt gtgccagatg tctcatgaaa ctatgaaatg gattggtgcg
    35821 ttaaacattt tttcttatta tcttttagat tttggagaga tggttaacgt ctgtattcca
    35881 gaaactcgat gattatttaa taaattagtt tcaatgatgc ttctaggtta tgactgtaat
    35941 gaaaaaggta ttaatagcag cgataggttt ttgtttagtt ggttgtgcag gtatgaaatt
    36001 acctgagtat tcgcaagtta aagcaagtcc gtattataca gattgccgtg cgtttgccat
    36061 ggatgtttat aaaaatgatg gatacagcaa aattgcgaaa actactatcc ttagcatgga
    36121 tgatgtgaag gctagatata ttgtgacagg gtgtgtagtt gctatgggga aaaacactgt
    36181 agaggaaatc aaagctgatc tctctgctaa agggagttct tttgggctta tcagtggagc
    36241 ttgttctagt gcggcatgtc gggttgatgt agagcagcaa atgaacgctt atgtacttgg
    36301 tagttattat gctgcaaata aaaaattccc ggataaaatg aaagcagagt tttaagtaaa
    36361 ccttgttttc gattatatgt cgaagataaa tgttagtaac ggcataataa gtaaatatat
    36421 agctgtgata gcaacccgcc actgagcggg ttttttgtac ctgtaaactt ggtgcagtac
    36481 agtaaacacg ctggtggtcg tgaatactga ctttttatct tgctggcttt ttagacaaga
    36541 gttattggta tgtcatgtta accagaaggg aaaaagatat gctaaaacag caagatatga
    36601 cagaaaccgc cgccgcagtc cttcatttct tacctgctga caagtgggta acgccacgca
    36661 tgatgacgag aactaccgga gtaagcgaag cccggtgcca gttaatactg actcagttag
    36721 ttctggcggg tctggcgaag gataacggcg ggtacgggaa taaattcaga cgctgccagt
    36781 aatggcggtt tcctgctgtg aaaatgggcg gctggtgggt gttggtagca cctgccagcc
    36841 attcgctcat gcttactggt cacaagcgaa ccatggccca ctgctttagc gcaaaagcag
    36901 agtgagccta ccagagttac gcttactgat ccatgaaaaa tactgtaaaa ataaacagtg
    36961 ttgatttaat caacgctgat tgcctgcatt ttattcagtc cctgcctgat gattccattg
    37021 acctgattgt taccgatccg ccgtacttca aggtgaaacc caacggctgg gacaatcagt
    37081 ggaaagggga cgaagattac cttaagtggc tggaccactg tctggcccag ttctggcggg
    37141 tgttaaaacc tgccggaagc ctttacctgt tctgtgggca tcgcctggca tctgatattg
    37201 agatcatgat gcgtgaacgt ttcaacgtgc ttaaccatat catctgggcg aagccgtccg
    37261 gacgttggaa tgggtgtaat aaagaaagtc tgcgcgcata ttttcctgcc acagagcgcg
    37321 ttctgtttgc tgaacattac caggggccat atcgcggcaa aagtgacggc tatgcagcaa
    37381 aagaaaggga actcaaacag cacataatgg caccgctgat atcgtatttc agggatgctc
    37441 gtgccgaact gggtataacg gcaaaacaaa ttgccgaagc cacaggtaag aaaaatatgg
    37501 tttcccactg gtttggtgcc agtcagtggc agttgccgaa tgaggctgac tatcggaagt
    37561 tacaggcact gttttcccgt atagcggcag agaagtttca ggaacaacaa ctggaacaac
    37621 cacaccacca gctggtggca tcttatgatt cactgaatcg taaatattct gaattgctgg
    37681 atgagtttaa atctctccgg cgctatttct ccgtatcagt ctccgtgcct tataccgatg
    37741 tctggatgca taaacccgtt cagttctacc cggggaaaca tccgtgtgag aaaccggcgg
    37801 atatgctcag gcaaataatc aatgccagta gtcgacctgg tgatctggtt gctgattttt
    37861 ttatgggatc cggttccaca ataaaagcag caatggcgct ggggcgtcgg gccttaggtg
    37921 ttgagcttga gtcagagcgg tttaaccaga cagtgaaaga gataaacgag ctggtgggga
    37981 aataatctgg tggccacgtc aggtggcctt tttatttcca ttacacagca cccgcatctg
    38041 cgaggtgggg ttatgaaatc catggataag ttaacaacgg gtgtcgccta tggcacctca
    38101 gcaggtagtg ccgggtactg gtttttacag ttgctcgata aagtcacgcc ctcacagtgg
    38161 gcggcaatag gtgtgctggg tagtctggta tttggcctgc tgacgtacct gacaaacctt
    38221 tatttcaaga ttaaagaaga taagcgcaag gctgcgagag gtgaataatg cctccatcat
    38281 tacgaaaagc agttgctgct gctattggtg gcggagcaat tgctatagca tcagtgttaa
    38341 tcactggccc aagtggtgac gatggcctgg aaggtgtcag ctacatacca tacaaagata
    38401 tcgttggcgt atggactgta tgtcacggac acaccggaaa agacatcatg ctcggtaaaa
    38461 cgtataccga agcagaatgc aaagccctcc tgaataaaga ccttgccacg gttgccagac
    38521 aaattaaccc gtacatcaaa gtcgatatac cggaaacaac gcgcggcgct ctttactcgt
    38581 tcgtctacaa cgtgggtgct ggcaatttca gaacatcgac gcttcttcgc aaaataaacc
    38641 agggcgatat caaaggcgca tgtgaccagc tacgtcgctg gatatacgct ggcggtaagc
    38701 aatggaaagg cctgatgact cgtcgtgaga ttgagcgtga agtctgtttg tgggggcaac
    38761 aatgagcaga gtaaccgcga ttatctccgc tctggttatc tgcatcatcg tctgcctgtc
    38821 gtgggcggtc aatcattacc gtgataacgc catcgcctac aaagaacagc gagataaaaa
    38881 agtcagtgag ctgaagcagg cgaccgccac cattactgac atgcagcagc gccagcgttc
    38941 tgctgatgca ctcgatgcta aatacacgaa ggagttagct gatgcgaaag ctgaaaatga
    39001 tgctcttcgg cgcaagcttg ataatggtgg tcgggtgttc gtcaaaggaa aatgccctgt
    39061 gccatcctca gccgaaacct ccagcgcctc cggcatgggc aatgatgcca ccgtcgaact
    39121 ctctccagtt gctggacgaa acgttctcgg tatccgggac ggaataatcc gcgaccaaac
    39181 agcactgaga acgcttcagg aatacatcag gacgcaatgc cttcgatgat agcgataatt
    39241 ttactcatca tccttcacat ctggctctgt agacaggatg gtgatcactt ctggagtgaa
    39301 tccagattaa acatctcatt gctgatgctt gatattgagc atcttgcgcg cggtaagggg
    39361 ctgcgttgag ataagagcca gtcattacaa ataccaggat ttagcctcgc attcgcgggg
    39421 ctttttattg ccattacaaa agccactccc tacagagtgg ctttgataat ggcttatacc
    39481 ctacacggga tagcttaact gatatccctt ttaacggata aaggtattca agcctgacac
    39541 atcatgcgct gtatcgtcgc cgtattcccg tattaacaga gaccgtagcc cgacggggaa
    39601 ctccttctgc gcgagtgtgc gggaataatc aaaaacgatg cacaccgggg ttaccgggta
    39661 cacatatttc atcatgccag cgagtccggt tctggcgcgg aagaaaccgg acgttatgat
    39721 ttagtgcgga aatatttgtg tagtgttctg aatgttctca gtaaagagta atgaattatc
    39781 aaaggtatag taataccttt tgttttcgtg gatatttgta atccatctga aaacccctgc
    39841 tgtagcaaga tttttcctgt attcgtaaaa tgataactct cctgatttga atccttttaa
    39901 tgtggcttct ataaggcatt tattttttga aaatcttaca tttacaacct taccctgtcc
    39961 ttttattaaa accgtattat cgttttcaag aacaagatga atattctctg tggctaaata
    40021 gtaaatgtaa tgtgagacat tgtgacgttt tagttcagaa taaaaccagt gatagtttaa
    40081 attatttcgc actttatcga atatttgttt aaaaatggca acctgagcca ttgtagtacc
    40141 ttccatgtga tatgaggggc gtagtctgca cgattatcta aattgcttca atctggtctg
    40201 atctgttttc tgagcaattc agtaatgtca ctcttttctt tgtttgcttc aggagaaact
    40261 cttttttctg agcacagtct ccggcggcag gcttcaatga cccaggctga gaaattcccg
    40321 gacccttttt gatcaagagc gatgttaatt tgttcaatca tttggttagg aaagcggatg
    40381 ttgcgggttg ttgttctgcg ggttctgttc ttcgttgaca tgaggttgtc ccgtattcag
    40441 tgtcgctgat ttgtattgtc tgaagttgtt tttacgttaa gttgatgcag atcaattaat
    40501 atgatacctg cgtcataatt gattatttga cgtggtttga tggcgtagat gcacgttgtg
    40561 acatgcagat gataattatt atcattttgc gggtcctttc cggcgatccg acaggttacg
    40621 gggcggcgac ctcgcgggtt ttcgctattt atgaaaattt tccggtttaa ggcgtttccg
    40681 ttcttcttcg tcataactta atgtttttat ttaaaatacc ctctgaaaag aaaggaaacg
    40741 acaggtgctg aaagcgagct ttttggcctc tgtcgtttcc tttctctgtt tttgtccgtg
    40801 gaatgaacaa tggaagtcaa caaaaagcag ctggctgaca ttttcggtgc gagtatccgt
    40861 accattcaga actggcagga acagggaatg cccgttctgc ggggtggtgg gaagggtaat
    40921 gaggtgcttt atgattctgc cgccgtcata aaatggtatg ccgaaaggga tgctgaaatt
    40981 gagaacgaaa agctgcgccg ggaagttgaa gaactgcggc aggccagcga gacagatctc
    41041 cagccaggga ctattgagta cgaacgccat cgacttacgc gtgcgcaggc cgacgcacag
    41101 gagctgaaaa atgccagaga ctccgctgaa gtggtggaaa ccgcattctg tactttcgtg
    41161 ctgtcgcgga tcgcaggtga aattgccagt attctcgacg ggatccccct gtcggtgcag
    41221 cggcgttttc cggaactgga aaaccgacat gttgatttcc tgaaacggga tatcatcaaa
    41281 gccatgaaca aagcagccgc gctggatgaa ctgataccgg ggttgctgag tgaatatatc
    41341 gaacagtcag gttaacaggc tgcggcattt tgtccgcgcc gggcttcgct cactgttccg
    41401 gccggagcca cagaccgccg ttgaatgggc ggatgccaat tactatctcc cgaaagaatc
    41461 cgcataccag gaagggcgct gggaaacact gccctttcag cgggccatca tgaatgcgat
    41521 gggcagtgac tacgtccgcg aggtgaatgt ggtgaagtct gcccgtgttg gttattccaa
    41581 aatgctgctg ggtgtttatg cctacttcat agagcataag cagcgcaaca cccttatctg
    41641 gttgccgacg gatggtgatg ccgagaactt tatgaaaacc cacgttgagc cgaccatccg
    41701 cgatattccg tcactgctgg cgctggctcc gtggtatggc aaaaagcacc gggataacac
    41761 gctcaccatg aagcgttttt ccaatggtcg tggcttctgg tgcctgggcg gtaaagcggc
    41821 aaaaaactac cgtgaaaagt cggtggatgt ggcgggttat gatgaacttg ctgcctttga
    41881 tgaggatatt gaacaggaag gctctccgac gttcctgggc gataagcgta ttgaaggctc
    41941 ggtctggcca aagtccatcc gtggctccac gcccaaagtg agaggcacat gccagattga
    42001 gcgtgcagcc agtgaatccc ctcattttat gcgttttcat gttgcctgcc cgcactgcgg
    42061 ggaggagcag taccttaaat ttggcgataa agagacgccg tttggcctca aatggacgcc
    42121 ggatgacccc tccagcgtgt tttatctctg cgagcataac gcctgcgtca tccgtcagca
    42181 ggagctggac ttcactgatg cccgttatat ctgcgaaaag accgggatct ggacccgtga
    42241 tggcattctc tggttttcgt catccggtga agagattgaa ccgcctgaca gtgtgacctt
    42301 tcacatctgg acagcgtaca gcccgttcac cacctgggtg cagattgtca aagactggat
    42361 gaagacgaaa ggggatacgg gaaaacgtaa aaccttcgtg aacaccacgc tcggtgagac
    42421 gtgggaagcg aaaatcggcg aacgtccgga tgctgaagtg atggcagagc ggaaagagca
    42481 ttattcagcg cccgttcctg atcgtgttgc ttacctgacc gccggtatcg actcccagct
    42541 ggaccgctac gaaatgcgcg tatggggatg ggggccgggt gaggaaagct ggctgattga
    42601 ccggcagatt attatgggcc gccacgatga tgaacagacg ctgctgcgtg tggatgaggc
    42661 catcaataaa acctataccc gccggaatgg tgcagaaatg tcggtatccc gtatctgctg
    42721 ggatactggc gggattgacc cgaccattgt gtatgaacgc tcgaaaaaac atgggctgtt
    42781 ccgggtgatc cccattaaag gggcatccgt ctacggaaag ccggtggcca gcatgccacg
    42841 taagcgaaac aaaaacgggg tttaccttac cgaaatcggt acggataccg cgaaagagca
    42901 gatttataac cgcttcacac tgacgccgga aggggatgaa ccgcttcccg gtgccgttca
    42961 cttcccgaat aacccggata tttttgatct taccgaagcg cagcagctga ctgctgaaga
    43021 gcaggtcgaa aaatgggtgg atggcaggaa aaaaatactg tgggacagca aaaagcgacg
    43081 caatgaagca ctcgactgct tcgtttatgc gctggcggcg ctgcgcatca gtatttcccg
    43141 ctggcagctg gatctcagtg cactgctggc gagcctgcag gaagaggatg gtgcagcaac
    43201 caacaagaaa acactggcag attacgcccg tgccttatcc ggagaggatg aatgacgcga
    43261 caggaagaac ttgccgctgc ccgtgcggca ctgcatgacc tgatgacagg aaaacgggtg
    43321 gcaacggtac agaaagacgg acggcgagtg gagtttacgg ccacttccgt gtctgacctg
    43381 aaaaaataca ttgcggagct ggaagtgcag accggcatga cacagcgacg caggggacct
    43441 gcaggatttt atgtatgaaa acgtccacca ttcccaccct tctggggccg gacggcatga
    43501 catcgctgcg tgaatatgcc ggttatcacg gcggtggcag cggatttggt gggcagttgc
    43561 gggcgtggaa cccaccgggt gaaagtgtgg atgcagccct gctgcccaac tttacccgtg
    43621 gcaatgcccg cgcggacgat ctggtacgca ataacggcta tgccgccaac gccatccagt
    43681 tgcatcagga tcatatcgtc gggtcttttt tccggctcag tcatcgccca agctggcgct
    43741 atctgggcat cggggaggaa gaagcccgtg ccttttcccg cgaggttgaa tcggcatgga
    43801 aagagtttgc cgaggatgac tgctgctgca ttgacgttga gcgaaaacgc acgtttacca
    43861 tgatgattcg ggaaggtgtg gccatgcacg cctttaacgg tgaactgttc gttcaggcca
    43921 cctgggatac cagtccgtcg cggcttttcc ggacacagtt ccggatggta agcccgaagc
    43981 gcatcagcaa cccgaacaat accggcgaca gccggaactg ccgtgccggt gtgcagatta
    44041 atgacagcgg tgcggcgctg ggatattacg tcagcgagga cggctatcct ggctggatgc
    44101 cgcagaaatg gacatggata ccccgtgagt tacccggcgg gcgcgcctcg ttcattcacg
    44161 tttttgaacc cgtggaggac gggcagaccc gcggtgcaaa tgtgttttac agcgtgatgg
    44221 agcagatgaa gatgctcgac acgctgcaga acacgcagct gcagagcgcc attgtgaagg
    44281 cgatgtatgc cgccaccatt gaaagtgagc tggatacgca gtcagcgatg gattttattc
    44341 tgggcgcgaa cagtcaggag cagcgggaaa ggctgacggg ctggattggt gaaattgccg
    44401 cgtattacgc cgcagcaccg gtccgtctgg gaggcgcaaa agtgccgcac ctgatgccgg
    44461 gggactcact gaacctgcag acggctcagg acacggataa cggctactcc gtgtttgagc
    44521 agtcactgtt gcggtatatc gctgccgggc tgggtgtctc gtatgagcag ctttcccgga
    44581 attacgccca gatgagctac tccacggcac gggccagtgc gaacgagtcg tgggcgtact
    44641 ttatggggcg gcgaaaattc gtcgcatccc gtcaggcgag ccagatgttt ctgtgctggc
    44701 tggaagaggc catcgttcgc cgcgtggtga cgttaccttc aaaagcgcgc ttcagctttc
    44761 aggaagcccg cagtgcctgg gggaactgcg actggatagg ctccggtcgt atggccatcg
    44821 atggtctgaa agaagttcag gaagcggtga tgctgataga agccggactg agcacctacg
    44881 agaaagagtg cgcgaaacgc ggtgatgact atcaggaaat ttttgcccag caggtccgtg
    44941 aaacgatgga gcgtcgtaca gccggtctta aaccacccgc ctgggcggct gcggcatttg
    45001 aatccgggct gcgacaatca acagaggagg agaagagtga cagcagagct gcgtaatctc
    45061 ccgcatattg ccagcatggc ctttaatgag ccgctgatgc ttgaacccgc ctatgcgcgg
    45121 gttttctttt gtgcgcttgc aggccagctt gggatcagcc gcctgacgga tgcagtatcc
    45181 ggcgacagcc tgactgccgg agaggcaccc gcggcgctgg cgttatccgg tgatgatgac
    45241 ggaccacgac aagcccgcag ttatcaggtc atgaacggca tcgccgtgct ggcggtgtcc
    45301 ggcacgctgg tcagccggac gcgggcgctg cagccgtatt cgggaatgac cggttacaac
    45361 ggcattatcg cccgtctgca acaggctgcc agcgacccga tggtggatgg cattctgctc
    45421 gatatggata cgccaggcgg gatggtggca ggggcatttg actgcgctga catcatcgcc
    45481 cgtgtgcgtg acataaagcc ggtatgggcg ctggccaatg acatgaactg cagcgcaggt
    45541 cagctgcttg ccagtgccgc ctcccggcgt ctggtcacgc agaccgcccg gacaggctcc
    45601 atcggcgtca tgatggctca cagtaattac ggtgctgcgc tggagaaaca gggcgtggaa
    45661 atcacgctga tttacagcgg cagccataag gtggatggca acccctacag ccatctaccg
    45721 gatgatgtcc gggagacact gcagtcccgg atggatgcaa cccgccggat gtttgcgcag
    45781 aaggtgtcgg catataccgg cctgtccgtg caggctgtgc tggataccga ggctgcagtg
    45841 tacagcggtc aggaggccat tgatgccgga ctggctgatg aacttgtcaa cagcaccgat
    45901 gcgatcaccg tcatgcgtga tgcactggat gcacgtaaat cccgtctctc aggagggcga
    45961 atgaccaaag agactcaatc aacaactgtt tcagccactg cttcgcaggc tgacgttact
    46021 gacgtggtgc cagcgacgga gggcgaaaac gccagcgcgg cgcagccgga cgtgaacgcg
    46081 cagatcaccg ctgcggttgc ggcagaaaac agccgcatta tggggatcct caactgtgag
    46141 gaggctcacg gacgcgaaga acaggcgcgc gttctggcag aaacccccgg aatgaccgtg
    46201 gaaacggccc gccgcattct ggccgcagca ccacagagtg cacaggcgcg cagtgacact
    46261 gcgctggatc gtctgatgca gggggcaccg gcaccgctgg ctgcaggtaa cccggcatct
    46321 gatgccgtta acgatttgct gaacacacca gtgtaaggga tgtttatgac gagcaaagaa
    46381 acctttaccc attaccagcc gctgggcaac agtgacccgg ctcataccgc aaccgcgccc
    46441 ggcggattga gtaagaaaac gccagcaatg actccgttga tgccggatac ctccacccgt
    46501 aagctggttg cgtgggatgg caccaccgac ggtgctgccg ttggcattct tgctgttgct
    46561 gctgaccaga ccagcaccac gctgacgttc tacaagtccg gcacgttccg ttatgaggat
    46621 gtgctctggc cggaggctgc cagcgacgag gcgaaaaaac ggaccgcgtt tgccggaacg
    46681 gcaatcagca tcgtttaacc tgacccttca tcactaaagg ccgcctgtgc ggcttttttt
    46741 acgggatttt tttatgtcga tgtacacaac cgcccagctg ctggcggcaa atgagcagaa
    46801 atttaagttt gatccgctgt ttctgcgtct ctttttccgt gagagctatc ccttcactac
    46861 ggagaaagtc tatctctcac aaattccggg actggtaaac atggcgctgt acgtttcgcc
    46921 gattgtttcc ggtgaggtta tccgttcccg tggcggctcc acctctgaat ttacgccggg
    46981 atatgtcaag ccgaagcatg aagtgaatcc gcagatgacc ctgcgtcgcc tgccggatga
    47041 agatccgcag aatctggcgg acccggctta ccgccgccgt cgcatcatca tgcagaacat
    47101 gcgtgacgaa gagctggcca ttgctcaggt cgaagagatg caggcagttt ctgccgtgct
    47161 taagggcaaa tacaccatga ccggtgaagc cttcgatccg gttgaggtgg atatgggtcg
    47221 cagtgaagcg aataacatca cgcagtccgg cagcacgggg tggagcaagc gcgacaagtc
    47281 cacgtatgac ccgaccgacg atatcgaagc ctacgcgctg aacgccagcg gtgtggtgaa
    47341 tatcatcgtg tttgacccga aaggctgggc gctgttccgt tccttcaaag ccgtcaggga
    47401 gaagctggat acccgtcgcg gctctcattc cgaactggag acagcggtaa aagacctggg
    47461 caaagcggtg tcttataagg gaatgtatgg cgatgtggcc atcgtcgtgt attccggaca
    47521 gtacgtggaa aacggcgtca aaaagaactt cctgccggac aacacgatgg tgctgggtaa
    47581 cactcatgca cgcggtctgc gcacctatgg ctgtattcag gatgcggatg cattgagtga
    47641 gggtattaat gcgtctcccc gttatccgaa aaactggaag acatccggcg atccggcgcg
    47701 agagttcacc atgattcagt cagcaccgct gatgctgctg gctgatcctg atgagttcgt
    47761 gtccgttcaa ctggcgtaat catggccctt cggggccatt ttctctctgt ggaggagtcc
    47821 atgacgaaag atgaactgat tgcccgtctc cgttcgctgg gtgagcaact gaaccgtgat
    47881 gtcagcctga cggggacgaa agaagaactg gcgctccgtg tggcagagct ggaagaggag
    47941 cttgatgaca cggatgacgc agccggtcag gacacgtctg tcagcccgga aaatgtgctg
    48001 accgtgcatg aaaatgaggt tgtatcagcg cagccggata ccgtgactga tacggctgat
    48061 ctggtcacgg ttgtggcact ggtgacgctg catactgatg cacttcacgc cacgcgggat
    48121 gaggctgtgg catttgtgct gccgggaacg gcgtttcgtg tctctgccgg tgtggcagct
    48181 gaaatgacag agcgcggcct ggccagaatg caataacggg aggcgctgtg gctgatttcg
    48241 ataacctgtt cgatgctgcc attgcctgcg ccgatgaaac gatacgcggg tacatgggaa
    48301 cgtcagccac catgacatcc ggtgagcagt ccggtgctgt gatacgtggt gtttttgatg
    48361 accctgaaaa tatcagctat gccggacagg gcgtgcgcgt tgaaggctcc agcccgtccc
    48421 tgtttgtccg gactgatgat gtgcggcagc tgcggcgcgg cgacatgctg accatcggtg
    48481 aggaaaactt ctggatagac cggatttcgc cggatgatgg cggaagctgt catctctggc
    48541 ttgggcgggg cgtaccgcct gccgttaacc gtcgccgctg aaagggggat gaatggccat
    48601 aaaaggtctt gagcaggccg ttgaaaacct cagccgtatc agcagaacgg cggtgcccgg
    48661 tgccgccgca atggccatta accgcgttgc gtcatccgcg atatcgcagt cggcgtcaca
    48721 ggttgcccgt gagacaaagg tacgccggaa actggtaaag gaaagggcca ggctgaaaag
    48781 ggccacggtc aaaaatccgc aggccagaat caaagttaac cggggggatt tgcccgtaat
    48841 caggctgggt aatgcgcggg ttgtcctttc gcgccgcagg cgtcgtaaaa aggggcagcg
    48901 ttcatccctg aaaggtggcg gcagcgtgct tgtggtgggt aaccgtcgta ttcccggcgc
    48961 gtttattcag caactgaaaa atggccggtg gcatgtcatg cagcgtgtgg ccgggaaaaa
    49021 ccgttacccc attgatgtgg tgaaaatccc gatggcggtg ccgctgacca cggcgtttaa
    49081 acaaaatatt gagcggatac ggcgtgaacg tcttccgaaa gagctgggct atgcgctgca
    49141 gcatcaactg aggatggtaa taaagcgatg aaacatactg aactccgtgc agccgtactg
    49201 gatgcactgg agaagcatga caccggggcg acgctttttg atggtcgccc cgctgctttt
    49261 gatgaggaag attttccggc aattgccgtt tatctcaccg gcgctgaata cacgggcgaa
    49321 gagctggaca gcgatacctg gcaggcggag ctgcatattg aagttttcct gcctgctcag
    49381 gtgccggatt cagagctgga ttcgtggatg gagtcccgga tttatccggt gatgagcgat
    49441 atcccggcgc tgtcagattt gatcaccagt atggtggcca gtggctatga ctaccggcgc
    49501 gacgatgatg cgggcctgtg gagttcagcc gatctgactt atgtcattac ctatgaaatg
    49561 tgaggacgat atgccaacac caaatcctct ggcaccggtg aaaggggccg ggaccaccct
    49621 gtgggtttat aacgggagcg gtgaccctta tgcgaatccg ctttcagacg ttgactggtc
    49681 gcgtctggca aaagttaaag acctgacgcc cggcgaactg accgctgagt cctatgacga
    49741 cagctatctc gatgatgaaa atgcggactg gactgcgacc gggcaggggc agaaatctgc
    49801 cggagatacc agcttcacgc tggcgtggat gcccggagag caggggcagc aggcgctgct
    49861 ggcgtggttt aataaagggg atacccgtgc ctataaaatc cgcttcccga acggcacggt
    49921 cgatgtgttc cgcggctggg tcagcagtat cggtaaggcg gtgacggcga aggaagtgat
    49981 cacccgcacg gtgaaagtca ccaacgtggg acgtccgtcg atggcagaag atcgcagcac
    50041 ggtaacagcg gcaaccggca tgaccgtgac gcctgccagc acttcggtgg tgaaagggcg
    50101 gagcatcacg ctgaccgtgg cattccagcc ggaaggcgca accgacaaga gcttccgtgc
    50161 ggtgtctgcg gataaaacaa aagccaccgt gtcggtcagt ggtatgacca tcaccgtgaa
    50221 aggtgttgct gcaggcaagg tcaacattcc ggttgtatcc ggtaatggtg aacttgctgt
    50281 ggttgcagga atcaccgtca ccgacagtta atccggagag tcagcgatgt tcctgaaaac
    50341 cgaatcattt gaatataacg gtatgagcgt cacgctttct gaactgtcag ccctgcagcg
    50401 aattgagcat ctcgccctgc tgaaacgaca ggcagaacag gcgggatcca gtctcaatcg
    50461 acaggtgagc gtggaagatc tcgtcagaac cggtgctttt ctggtggcga tgtccctgtg
    50521 gcataaccat ccgcagaaga caaagatgcc gtccatgaat gaagccgtta aacaaattga
    50581 gcaggaagtg cttaccacct ggcccacaga ggcaattgct caggctgaaa atgtggtaat
    50641 gcgtctgtcc ggtatgtctg agtttgttgt gaatgatgcc cctgaacagg cagaggacgc
    50701 cgggcctgca gagcctgttt ctgcgggaaa gtgttcgacg gtgagctgag ttttgccctg
    50761 aaactggcgc gtgagatggg gcgacctgac tggcgcgcca tgcttgccgg gatgtcatcc
    50821 acggagtatg ccgactggca ccgcttttac agtacccatt attttcatga tgttctgctg
    50881 gatatgcact tttccgggct gacgtacacc gtgctcagcc tgtttttcag cgatccggat
    50941 atgcatccgc tggatttcag tctgctgaac cggcgcgagg ctgacgaaga gcctgaagat
    51001 gatgtgctga tgcagaaagc ggcagggctt gccggaggtg tccgctttgg cccggacggg
    51061 aatgaagtta tccctacttc cccggatgtg gcggacatga cggaggatga cgtaatgctg
    51121 atgacagtat cagaagggat cgcaggagga gtccggtatg gctgaaccgg taggcgatct
    51181 ggtcgttgat ttaagtctgg atgcggccag atttgacgag cagatggcca gagtcaggcg
    51241 tcatttttcc ggtacggaaa ctgatgcgaa aaaaacagcg gcagtcgttg aacagtcgct
    51301 gagccgacag gcgctggctg cacagaaagc ggggatttcc gtcgggcagt ataaagccgc
    51361 catgcgtatg ctgcctgcac agttcaccga cgtggccacg cagcttgcag gcgggcaaag
    51421 tccgtggctg atcctgctgc aacagggtgg tcaggttaag gactccttcg gcgggatgat
    51481 ccccatgttc agggggcttg ccggtgcgat caccctgccg atggtggggg ccacctcgct
    51541 ggcggtggcg accggtgcgc tggcgtatgc ctggtatcag ggcaactcaa ccctgtccga
    51601 tttcaacaaa acgctggtcc tttccggcaa tcaggcggga ctgacggcag atcgtattct
    51661 ggccctgtcc agagccgggc aggcggcagg gctgacgttt aaccagacca gcgagtcact
    51721 gacggcgctg gtgaatgccg gtgtgcgtgg tggtgagcag tttgaggcga tcagccagag
    51781 tgtggcgcgt ttctcctctg catccggcgt ggaggtggac aaggtcgctg aagccttcgg
    51841 gaagctgacc acagacccga cgtcgggact gacagcgatg gcacgtcagt tccgtaacgt
    51901 gacggcggag cagattgcgt atgttgctca gttgcagcgt tccggagatg aagccggggc
    51961 attgcaggcg gcgaacgagg ccgcaacgaa agggtttgat gaccagaccc gccgcctgaa
    52021 agagaacatg ggcacgctgg agacctgggc agacaggaca gcacgggcat tcaaatccat
    52081 gtgggattcg gtgctggata ttggtcgccc ggacactgcc cagggaatgc tggagaaagc
    52141 agaaaaggct tttgatgagg cggacaaaaa atggcagtgg tatcagagtc ggagccaccg
    52201 gcgcggtaaa acctcagcat ttcttgccaa tctccgggga gcatgggagg acagagcgaa
    52261 tgcgcaactt gggctttcag ccgccacgtt gcaggccgat cttgaaaagg ccagagagat
    52321 ggcagcaaag gactgggccg agtctgaggc atcacggctg aaatataccg aagaggcgca
    52381 gaaggcttac gaacggctgc agacgccgct ggagaaatat accgcccgtc aggaagaact
    52441 gaacaaggca ctgaaagacg ggaaaatcct gcaggcggat tacaacacgc tgatggcggc
    52501 ggcgaaaaag gattatgaag cgacgctgaa aaagccgaaa cagtccggcg tgaaggtgtc
    52561 tgcgggcgat cgtcaggaag acagtgctca tgctgccctg ctgacgcttc aggctgaact
    52621 ccggacgctg gagaagcatg ccggagcaaa tgagaaaatc agccagcagc gccgggattt
    52681 gtggaaggcg gagagtcagt tcgcggtact ggaggaggcg gcgcaacgtc gccagctgtc
    52741 tgcacaggag aaatccctgc tggcgcataa agatgagacg ctggagtaca aacgccagct
    52801 ggctgcactt ggcgacaagg ttacgtatca ggagcgcctg aacgcgctgg cgcagcaggc
    52861 ggataaattc gcacagcagc aacgggcaaa acgggccgcc attgatgcga aaagccgggg
    52921 gctgactgac cggcaggcag aacgggaagc cacggaacag cgcctgaagg aacagtatgg
    52981 cgataatccg ctggcgctga ataacgtcat gtcagagcag aaaaagacct gggcggctga
    53041 agaccagctt cgcgggaact ggatggcagg cctgaagtcc ggctggagtg agtgggaaga
    53101 gagcgccacg gacagtatgt cgcaggtaaa aagtgcagcc acgcagacct ttgatggtat
    53161 tgcacagaat atggcggcga tgctgaccgg cagtgagcag aactggcgca gcttcacccg
    53221 ttccgtgctg tccatgatga cagaaattct gcttaagcag gcaatggtgg ggattgtcgg
    53281 gagtatcggc agcgccattg gcggggctgt tggtggcggc gcatccgcgt caggcggtac
    53341 agccattcag gccgctgcgg cgaaattcca ttttgcaacc ggaggattta cgggaaccgg
    53401 cggcaaatat gagccagcgg ggattgttca ccgtggtgag tttgtcttca cgaaggaggc
    53461 aaccagccgg attggcgtgg ggaatcttta ccggctgatg cgcggctatg ccaccggcgg
    53521 ttatgtcggt acaccgggca gcatggcaga cagccggtcg caggcgtccg ggacgtttga
    53581 gcagaataac catgtggtga ttaacaacga cggcacgaac gggcagatag ggccacaggc
    53641 gctgaaggct gtttatgacg tagcccgtaa ggcggcaatg gatgttgtga ccgggcagat
    53701 gcgcgatggt ggcctgttct ccggaggtgg acgatgaaga ccttccgctg gaaagtgaaa
    53761 cccggtatgg atgtggcttc ggtcccttct gtaagaaagg tgcgctttgg tgatggctat
    53821 tctcagcgag cgcctgccgg gctgaatgcc aacctgaaaa cgtacagcgt gacgctttct
    53881 gtcccccgtg aggaggccac ggtactggag tcgtttctgg aagagcacgg gggctggaaa
    53941 tcctttctgt ggacgccgcc ttatgagtgg cggcagataa aggtgacctg cgcaaaatgg
    54001 tcgtcgcggg tcagtatgtt gcgtgttgag ttcagcgcag agtttgaaca ggtggtgaac
    54061 tgatgcagga tatccggcag gaaacactga atgaatgcac ccgtgcggag cagtcggcca
    54121 gcgtggtgct ctgggaaatc gacctgacag aggtcggtgg agaacgttat tttttctgta
    54181 atgagcagaa cgaaaaaggt gagccggtca cctggcaggg gcgacagtat cagccgtatc
    54241 ccattcaggg gagcggtttt gaactgaatg gcaaaggcac cagtacgcgc cccacgctga
    54301 cggtttctaa cctgtacggt atggtcaccg ggatggcgga agatatgcag agtctggtcg
    54361 gcggaacggt ggtccggcgt aaggtttacg cccgttttct ggatgcggtg aacttcgtca
    54421 acggaaacag ttacgccgat ccggagcagg aggtgatcag ccgctggcgc attgagcagt
    54481 gcagcgaact gagcgcggtg agtgcctcct ttgtactgtc cacgccgacg gaaacggatg
    54541 gcgctgtttt tccgggacgt atcatgctgg ccaacacctg cacctggacc tatcgcggcg
    54601 atgagtgcgg ttatcacggt ccggcggtcg cggatgaata tgaccagcca acgtccgata
    54661 tcacgaagga taaatgcagc aaatgcctga gcggttgtaa gttccgcaat aacgtcggca
    54721 actttggcgg cttcctttcc attaacaaac tttcgcagta aatcccatga cagagacaga
    54781 atcagcgatt ctggcgcacg cccgccgatg tgcgccagcg gagtcgtgcg gcttcgtggt
    54841 gaaaacgccg gagggagaaa gatattttcc ctgcgtgaat atctccggtg agccggagga
    54901 gtatttccgg atgtcgccgg aggactggct gcgggcagag atgcagggtg agattgtggc
    54961 actggtccac agccaccccg gtggtctgcc ctggctgagt gaggccgacc ggcggctgca
    55021 ggtgcagagt gatttgccgt ggtggctggt ctgccggggg gcgattcata aattccgctg
    55081 tgtgccgcat ctcaccgggc ggcgctttga gcacggggtg acggactgtt acacgctgtt
    55141 ccgggatgct taccatctgg cggggattga gatgccggat tttcatcgcg gggatgactg
    55201 gtggcgtaac ggtcagaatc tctatctgga taatctggag gctacagggc tgtatcaggt
    55261 gccgttgtca gcggcgcagc cgggcgatgt gctgctgtgc tgttttggtt catcggtgcc
    55321 gaatcatgcc gctatttact gcggcgacgg cgagctgctg caccatattc ctgaacaact
    55381 gagcaaacga gagaggtata ccgacaaatg gcagcgacgc acacactccc tctggcgtca
    55441 ccgggcatgg cacgcatctg cctttacggg gatttgcaac gatttggccg ccgcatcgat
    55501 cttcgtgtga aaacgggggc cgaagccatc cgggcgctgg ccactcagct cccggcgttt
    55561 cgtcagaaac tgaataaggg ctggtatcag gtgcgcattg ctgggcgtga tgcaggcgaa
    55621 aatgaattat ctgcccgtct taatgagccg ctggcaaatg gtgccgtgat ccacatcgtg
    55681 ccgcgtctgg cgggagctaa aagtggcggt gtgtttcagg tggtgcttgg ggcggcgctg
    55741 attgcggtgg catggtggaa ccctgtgggc tggctgggtg ccgcggctgt atcgggcatg
    55801 tatgcggcag gggccagtat gatcctgggc ggagtggcgc agatgctggc accgaaagcc
    55861 aggacgccca cggcagccag tacagataac ggcaaacaga acacctattt ctcctcactg
    55921 gataacatgg ttgcccaggg caatgttctg cctgttctgt acggtgaaat gcgcgtgggg
    55981 tcgcgggtgg cttctcagga gatcagcacg gcagacgaag gggatggtgg tcaggttgtg
    56041 gtgattggtc gttgatgaaa aacgttttat gtgaaaccgc ctccgggcgg ttttgtcgtt
    56101 tctggagcgt gaggaatggg taaaggcagc agtaaggggc ataccccgcg cgaagcgaag
    56161 gacaacctga aatcatccca gatgctgagc gtgatagacg ccatcagtga agggccgatt
    56221 gaaggtccgg tggacggatt aaaaagtgtg ctgctgaaca gtacgccagt gctggacagt
    56281 gaggggaata ccaatatctc cggtgtcacg gtggtgttcc gggcaggtga gcaggagcag
    56341 acaccgccgg agggatttga atcctccggc tccgagacgg tgctgggtac ggaagtgaag
    56401 tacgacacgc cgattacccg gaccatcacg tctgcaaaca tcgaccgtct gcgctttacc
    56461 ttcggtgtgc aggcactggt ggaaaccacc tcaaaggggg accggaatcc gtcggaagtc
    56521 cgcctgctgg ttcagataca acgtaacggt ggctgggtga cggaaaaaga catcaccatt
    56581 aagggaaaaa ccacctcaca gtatctggcc tcggtggtgg tgggtaacct gccgccgcgc
    56641 ccgtttaata tccggatgcg caggatgacg ccggacagca ccacagacca gctgcagaac
    56701 aaaacgctct ggtcgtcata caccgaaatc atcgatgtga aacagtgcta cccgaacacg
    56761 gcactggtcg gcgtgcaggt ggactcggag cagttcggca gccagcaggt gagccgtaat
    56821 tatcatcttc gcgggcgcat tctgcaggtg ccgtcgaact ataacccgca gacgcggcaa
    56881 tacagcggta tctgggacgg aacgtttaag ccggcataca gcaacaaccc ggcctggtgt
    56941 ctgtgggata tgctgaccca cccgcgctac ggcatgggga aacgtcttgg tgcggcggat
    57001 gtggataaat gggcgctgta tgtcatcggc cagtactgcg accagtcagt gccggacggt
    57061 tttagcggca cggagccgcg catcacctgt aatgcctggc tgaccacaca gcgtaaggcg
    57121 tgggatgtgc tcagtgattt ctgctcggcg atgcgctgta tgccggtatg gaacgggcag
    57181 acgctgacgt tcgtgcagga ccgaccatca gataaggtgt ggacctataa ccgcagtaat
    57241 gtggtgatgc cggatgatgg cgcgccgttc cgctacagct tcagcgccct gaaggaccgc
    57301 cataatgccg ttgaggtgaa ctggattgac ccggacaacg gctgggagac ggcgacagag
    57361 cttgttgaag atacgcaggc cattgcccgt tacggtcgta atgtcacgaa gatggatgcc
    57421 tttggctgta ccagccgggg gcaggcacac cgcgccgggc tgtggctgat taaaacggaa
    57481 ctgctggaga cgcagaccgt ggatttcagc gtgggtgctg aagggcttcg ccatgtaccg
    57541 ggcgatgtca ttgaaatctg cgatgatgac tatgccggta tccgcaccgg cgggcgcgtg
    57601 ctggcggtaa acatccagac ccggacgctg acgctcgacc gtgaaatcac gctgccatct
    57661 tccggcacca cgctgataag cctggttgac gggcagggga gtccggtcag cgtggaggtt
    57721 cagtccgtca ccgacggcgt gaaggtgaaa gtgagccgtg ttcctgacgg cgttgctgaa
    57781 tacagcgtat gggggctgaa gctgccgacg ttgcgccagc gcctgttccg ctgcgtgagt
    57841 atccgtgaga acgacgacgg cacgtatgcc atcaccgccg tgcagcatgt accggaaaaa
    57901 gaggccatcg tggataacgg ggcgcacttt gacggcgacc agagcggcac ggtaaatggt
    57961 gtcacgccgc cagcggtgca gcacctgacc gcagaagtca ccgcagacag cggggaatac
    58021 caggtgctgg cccgctggga cacgccgaag gtggtgaagg gcgtgagctt cctgcttcgc
    58081 ctgaccgtgg cagcggatga cggccgtgag cggctggtca gcacggcccg gacgacggaa
    58141 accacttacc gcttcacaca actggctctg gggaactaca ggctgacagt ccgggcagta
    58201 aatgcgtggg ggcagcaggg cgatccggcg tcggtatcgt tccggattgc cgcaccggca
    58261 gcgccgtcgc ggattgagct gacgccgggc tattttcaga taaccgccac gccgcatctt
    58321 gcggtttatg acccgacggt acagtttgag ttctggttct cggaaaaacg gattgcggat
    58381 atcaggcagg ttgaaaccag cgcgcgttat cttggtacgg cactgtactg gatagccgcc
    58441 agtatcaata tcaaaccggg ccatgattat tatttttacg ttcgcagtgt gaacaccgtt
    58501 ggcaaatcgg cattcgtgga ggctgtcggt cagccgagtg atgatgcatc aggctatctg
    58561 gattttttca aaggcgagat agggaaaacc catctggctc aggagctgtg gacgcagatt
    58621 gataacggtc agcttgcgcc tgacctgact gaaatcagga cgtccataac ggatgtcagc
    58681 aatgaaataa cacagaccgt caataagaaa ctggaagacc agagtgcagc gatccagcag
    58741 atacagaagg ttcaggttga tacaaataat aacctgaaca gcatgtgggc agtgaagctg
    58801 cagcagatgc aggacggacg cctttatatc gcgggtatcg gtgccggtat tgagaacacc
    58861 cctgacggca tgcagagtca ggtgctgctg gcagcagaca ggattgcgat gattaatcct
    58921 gcgaatggca acacaaagcc gatgtttgtt ggtcagggcg atcagatatt catgaatgaa
    58981 gtgttcctga aacgcctgac ggcccccacc attaccagcg gcggtaatcc tccggcattt
    59041 tccctgacat cagacgggag actgacggcg aaaaatgcgg atatcagtgg cagtgtgaat
    59101 gcgaactcag gaacgctcaa caatgtcacg attaaccaga actgtacgat taagggcatg
    59161 ctggaggcga cccaggtcag aggagatttc gttaaagctg tatcaaaagc cttcccgaaa
    59221 aaagtcggta cgtggggtaa cacggaaaca ccaaacggta cggttacagt caccatcagc
    59281 gatgatcata actttgaccg ccagattatt attccgccca ttatttttaa cggtatagcg
    59341 tatgacgatc cggggagcgg aaataaccca ggaggcacaa gatacacggg ttatggtttt
    59401 gaagttcgca aaaacggcgt attaatcgca tccagagaaa ctaaaggggc cattcccggt
    59461 agttacagtg cagttattga tatgccgagt ggcaggggaa gcgtcactct ggagtttaag
    59521 attttccaga aaggcaatca gggggcaggc aatatcaccg actgtacggt gattgtgacc
    59581 aaaaaagccg cttccggcat cagtattcgt tgaaatattt ataaccccaa taaagggcgt
    59641 caggaatgac gcctttttta ttgcagaaaa gcgagaggta attatgcgta aagtttgtgc
    59701 agcaattttg tccgcagcca tttgtctggc cgtatccggt gcgcctgcat gggcgtctga
    59761 acatcagtcc acgctgagcg cggggtatct tcatgcctcg acgaacgtcc ccggcagtga
    59821 tgatctgaac gggattaacg tgaaataccg ttatgagttt acggacacac tggggctggt
    59881 gacgtcattc agctatgcag gagacaagaa tcgccagctg acccgttaca gcgatacccg
    59941 ctggcatgaa gattccgttc gtaaccgctg gttcagcgta atggcggggc cgtctgtgcg
    60001 cgtgaatgaa tggttcagcg cgtatgcgat ggcgggtgta gcttacagcc gtgtgtcgac
    60061 tttctccggg gattatatcc gcgtaactga caataagggg aaaacgcacg atgtgctgac
    60121 cggaagtgat gacggtcgcc acagcaacac gtctctggcg tggggggctg gcgtgcagtt
    60181 taacccgacc gagtccgtgg ccattgatgt cgcttatgaa ggttccggca gtggcgactg
    60241 gcgcactgac ggtttcatcg tgggtgtcgg ttataaattc tgattagcca ggtaacacag
    60301 tgttatgaca gcccgccgtt tcaggcgggc ttttttgtgg ggtgaatatg gcagtaaaaa
    60361 tttcaggtgt actgaaagac ggcacaggaa aaccggtaca gaactgcaca atccagctga
    60421 aagcaaaacg taacagtacc acggtggtgg tgaacacgct ggcatctgaa aatccggatg
    60481 aagccgggcg ttacagcatg gacgttgagt acggtcagta cagcgttatt ctgttggtgg
    60541 aaggattccc gccgtcacat gccgggacca tcaccgtgta tgaagattcc cgacccggta
    60601 cgctgaatga ttttctcggt gccatgacgg aggatgatgc ccgtccggag gcactgcgcc
    60661 gttttgagct gatggtggaa gaggtggcgc gtaacgcgtc cgtggtggca cagaacacgg
    60721 cagccgcgaa gaagtcagcc agtgatgcca gcacatcagc ccgtgaggcg gcaacccatg
    60781 cgactgatgc tgcaggctca gcacgcgcag ccagcacatc agccgggcag gccgcgacgt
    60841 cggctcagtc agcgtcttcc agcgcaggaa cggcatcaac aaaggccact gaagcctcaa
    60901 aaagtgctgc cgctgcagag tcctcaaaaa gcgcggcagc taccagtgcc ggtgcggcga
    60961 aaacgtcaga aacgaatgcg gcagcgtcac aaaaatctgc agccacttct gcatccgcag
    61021 cgaccacaaa ggcgtcagaa gctgccacct cagcccggga tgcggcggcc tcaaaagagg
    61081 cagcgaaatc atcagaaacg aacgcatcat caagcgccag tagtgccgct tcctcggcaa
    61141 cggcggcagg aaattccgcg aaggcggcaa aaacgtccga gacgaacgcc aggtcttctg
    61201 aaacggcagc gggacagagt gcctcagctg cggcaggctc aaaaacagcg gctgcatcat
    61261 ctgccagtgc cgcatcaaca agtgccgggc aggcctcagc cagtgccacc gctgccggaa
    61321 agtcggcaga aagtgccgca tcgtctgctt caacagccac aacgaaggct ggcgaagcca
    61381 ctgaacaggc cagcgcagca gcgaggtcag cttccgcagc gaagacatcc gaaacgaacg
    61441 cgaaagcgtc ggaaacccgt gcagaatcct caaaaacggc tgccgcatcg tccgccagtt
    61501 cggcggcgtc atcggcatca tcggcgtctg cttcaaaaga tgaggcgacc agacaagcgt
    61561 cagcagcgaa gggcagcgcc acgacggcat ccacgaaggc gacagaggca gctggcagtg
    61621 cgacggcggc agctcagagc aaaagtacgg cggaatccgc ggcaacgcgc gccgagacag
    61681 cagcaaaacg ggcagaggat attgcatccg ctgtggcgct tgaggatgcg agcacgacga
    61741 aaaagggggt agtacagctc agcagtgcga ccaacagcac ttccgagtca caggcggcaa
    61801 cgccaaaagc cgttaaggcc gcgtatgacc tggctaacgg gaaatacacc gcacaggacg
    61861 ctacgacagc acaaaaagga attgtccagc tcagtagtgc aaccaacagc gcatctgaaa
    61921 cgcttgccgc gacaccgaaa gcagtgaaag cagctaatga taatgcgaat ggtcgggtac
    61981 cttctgcccg taaggtgaat ggtaaggcgc tttcagcgga tataacactg acgccgaaag
    62041 atattggtac gcttaactca acaacaatgt cattcagcgg tggtgctggt tggttcaaat
    62101 tagcaacggt aaccatgcca caggcgagtt ccatcgttta catcgcattg attggtggcg
    62161 ctggttacaa cgtcggttcc ccacatcagg caggcatttc agaactggtt ctacgagcag
    62221 gcaatggaaa ccccaaagga attaccgggg ctttgtggaa gcgtacagcc gtcggattaa
    62281 cgaatttcgc ctggatcaac acatccggcg atacatatga tatttacgtt gagattggca
    62341 attatgcgac gagtgtaaat atccattggg attgtactgc aaatgcgtca gtttctgttt
    62401 atacctcgcc aacatattca gcgagtaagc cttccagcgt tacctatggt gttgtttata
    62461 cgatgtatag cacacatcag aaaccgacgc cgttagatat tggagcactg ccaacaaccg
    62521 gaggaacagt ttcaggtccg ttgtctgtta caggtggatt aactggttca ttgaatggta
    62581 atgcaagtac agccacgaaa ttgcagacgg caagatctat cggtggagtt gttttcgacg
    62641 gttctgcaaa tattaacctt ccaggtgtaa acactacggg taatcagaac accactggta
    62701 atgctgcaac tgccacaaaa ctacagactg cacggaatat caacggcgtt ccgtttgacg
    62761 gcacgaagga tattacgctt acgcctaaag atctggatgc ctacagcaaa agcgaagtac
    62821 agagcgcact ggcgggcaaa caaccgctgg acaatacgct gactaatttg agtggaaagg
    62881 atgtagctgg tcttctcgca taccttggtt tgggcgaaac gataaataaa gcctccggag
    62941 ctatgcagaa atcggctaat ggagctgata tttctgatgt atcagccttc cgaaatgcgc
    63001 tccagttagg gaccgccgca acacgagatg ttggagcaga taatgcctcg aagttactgg
    63061 gtttagacag cttcaggtca atgatgtcag ggaatggcta catctacatt ccatgcattg
    63121 cgacgacagg aaacccggtg aaacttatgt tgcagtgggg aatggtggca acacaaaagg
    63181 gagctgatgc tggatatgcc ttaccatttg cttttcccta tgcaggctta tttgcgaccg
    63241 gaaaccgtgg aacatctggc tacaatgccg cgatgaatgt gcgtattgcc agcagaacgc
    63301 atatcagtat tcagaactgg tcgccatccg gagagggcac cgaagattgt tgttttatcg
    63361 cgctggggta ttaagaatga ataaatttta taaaggctct ttctatccga aagcactaaa
    63421 agaggtatat atcagcgccg gttcatggcc tgaaaatggc gttgatgttg atgatgaaac
    63481 aatggcaatt tacacaggcg tagcgccaca aggcaaaacg ctgggggctg ataaaaatgg
    63541 taatcctgcg tggattgata tcccgccact ctccgctgaa caacagatta ttcaggctga
    63601 acagaaaaga acggtattgc gttctatggc tgataaggaa atagcctgga gacaggatgc
    63661 ttttgatgcg gaaatcgcga cggcagaaga aaccgccgcg ttatctgaat ggaaaaaata
    63721 ccgggtcttg ctgatgcgcg ttgatacagc aaaacccgta tggcctgtca atccgcagga
    63781 tatttaacgg gggcgttgta ggtggtgaca tattcaagca gttctgttgg atatgtcacc
    63841 gttgctgcat ctcgctctac gttaaatgta tccgctcccc agataacaca ctccctcaaa
    63901 aatgcctcca cctctggcga gacttcaacc gcatcatcag gtcgctcttg ttcagaaaca
    63961 taaaaaccaa cggtcgttgg gctgaaatac atattctcca tatttagtat cctattgctt
    64021 caaaatgcaa agtcggaatt tcgccgagat tgggtgtcgt atacgacaca gtgaatcgcg
    64081 ttcttgatac gtcagtgcca gaatcagtat cgcgatgcgt tgccagtgat ttcccagcca
    64141 ttgatgactg ggtcgaaaag ctgtaactcg ctagtgttgc cagcgttgct atttgtgcat
    64201 ttgggaattg tctggggaaa ttaaccctgt agtaatgggt gtagtacagc actccaccaa
    64261 gagtaattgc gttgaaatta ccaacaggcg tcagtgtcac agtaccaacc tgtcgaatca
    64321 taccatttgg gagaatatcc caggcagttt gtccgtttcg cgacatacca aatgcggaca
    64381 tgtccgggag ttgattatta ccggttccga cattacgttt tgccgcttct cccaattgaa
    64441 cgtttatgaa aatgcagaaa tagcgcgcaa atggcatcgt tcctgttttt gtcaggagga
    64501 gctatcatgc ttattggcta tgttcgcgta tcaacaaatg accagaacac cgatctacaa
    64561 cgtaatgcgt tgaactgtgc aggatgcgag ctgatttttg aagacaagat aagcggtaca
    64621 aagtccgaca gaccaggact gaaaaagctg ctcaggacat tatcggcagg tgacacgctg
    64681 gtggtctgga aactggaccg actgaggcgc agtatgcggc atcttgtcgt gctggtggag
    64741 gaactgcgcg aaagaggcat caacttttgc aatctgacgg attcaattga tacacagtat
    64801 cttgttaaca ccaacacatg gctgcaggag ggatattatc ggtacccgat ttcaggatac
    64861 agcgcctgat tagactaaag aggggctata ttgtagagtt tgctaaattt ttttataggg
    64921 ttaagcaaat gacagtcagg aactacacta atttaaattt agatcggaca actattgagg
    64981 ctacgtctag ggcatttatt gaaaataaaa actattccgt ccattcaatt ggaccaatgc
    65041 ctggtgcaag agcaggactt cgggttgtgt ttgctaaacc aggagaagct ttggcaactg
    65101 ttaacatttt ctataataac ggagggacgt ctacagtcca gtatcaaaca ggagctaatc
    65161 ataatcttgg aaaagagttg gctgatgatc tctatgaaac catcaatcct gcagaatttg
    65221 aacaggtaaa tatggtgtta caagggttcg ttgaagcgaa cgttttatct gtacttcagc
    65281 tctcagcaga gcagccacat atacaatttt acgaatactt acggaacact catacaacgg
    65341 tgtggaaaat tcattcgcca gaatttcagg atgagttgac agttagtctg catcacagaa
    65401 atggaacact acaaatacaa gggcgtccat tgtcatgtta tagagtgttt atattcaact
    65461 tgtcagagct actcgattta caaggactgg aaaaagttct cattcgtcag gacgatggca
    65521 aagcgtatat agttcagaaa gaagttgctc gctcacatct agagtgtgaa atgggggatg
    65581 cgtacccact attgcataag aatgttgaaa aattgctcgt ttctgggctg tgtgttaaac
    65641 tcgccgcccc cgatttacct gattactgta tgttgttgta tcctgaatta cgttcagttg
    65701 agggagtact taaatcaaca atgtaccgat atggcatgcc aatcacgcag gatggtttcg
    65761 ggcgttattt tgataaaatt gggagtgaat ttattctgaa acaacaattt ggatgcaatt
    65821 tatcgtcagc taaggttaag accattaatg atgcctatac tttctttaac agagaacgtc
    65881 atggcctgtt tcatatggag atagttgtcg acacaagccg tatggtttct gacatggcac
    65941 gactgatgac taaggccaga caggcatggg gaattattaa ggatttgtat attgtttgaa
    66001 ataacaggtg ttaacgtctc aggggctctc attgccgtcg ttatggcgac tggctacgag
    66061 aaccccttga cttcagttca cgaaatcgag aagaggcttt ctgttatact gggcaattca
    66121 caggctacag gtgaggtttt gtttgacctt ttgtgttcta atggtccaga gtggaatcgc
    66181 tttgtttcgc tggaaataag gtgtggcagt attttgctgg atactgccaa aattgtggat
    66241 gagcaagaaa ttccagcgca gatcttgaga catcagagag atgtattacg taaccaccct
    66301 gagtacgtag aagactctgt gttaacacca gatgatgttc tttgtattct ctagctaaga
    66361 aattttgcac gagaggattt taacctcctc cccgacagac atgacagtgc ccaaatgtct
    66421 taagaacgta tgtacttgaa atggacattg ctaataccac tgggtattga ttaatttggg
    66481 gctggtaagc attacaaacc aataatctgg aatagcgcgg ttgctgctgc agacaatgct
    66541 gcaaatgaat tgtacttaga ttgaagccgc gcagtggcga agaaatcatg gagattcacg
    66601 ttaagttcgg gatcttcata cgtaaccatg acaatttttt tgcctaactc aacttttgct
    66661 gtagcagatt taatccataa aattgcagat aagacgccaa aagttaatga catcacatga
    66721 tgatctttaa tccaacacat cacaaaaagt agattttcca ttaatcacct tcctgataaa
    66781 gaacagtggc attacaaata aacaagaaat ctcctgtcgc aggtaccttg tcaatttaac
    66841 acccacatca ataaaggctg ttgttccgtt tgtggcagct gatgtataga catttttgca
    66901 gatgaaacga aaaagcccgc agatgcgggc tttcatgtca cttgggagcc gcggctcctt
    66961 tgcgtatcct tttttgtctg ctcaccgtct ggttggtgtc ctgctgagac tgctaacttc
    67021 ctgtttttat tggtgttgtc cttacaccgt ccaatcatga ttggtggagc tggcgggagt
    67081 tgaacccgca gacacgtcgt atgcaagaac ttgctgcggc tggatggtgg actttagtgc
    67141 gagtattgaa tgatttccat ctattataga ttttaccgta tttcggcatg aatgaaactg
    67201 aatatcctcc caccgaccct ccatgacttt acaccactgt ctctggggct gctatgtgcc
    67261 agtagaggac gttgctagtg tcagcctatg ttaatcaaca gggagcaggt cacactgtcg
    67321 tctcagaata c
//
LOCUS       DAPOAV010000013        65894 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.013, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000013 DAPOAV010000000
VERSION     DAPOAV010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 65894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65894
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.013"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            230..1129
                     /gene="lysO"
                     /locus_tag="RN951_001035"
     CDS             230..1129
                     /gene="lysO"
                     /locus_tag="RN951_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415395.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lysine exporter LysO"
                     /protein_id="HDX2526068.1"
                     /translation="MFSGLLIILVPLIVGYLIPLRQQAALKVINQLLSWMVYLILFFM
                     GISLAFLDNLASNLLAILHYSAVSITVILLCNIAALMWLERGLPWRNHHQQEKLPSRI
                     AMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQ
                     IVLNRRGMIVAVVVVVSSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFG
                     PVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMV
                     PAAIVHGFILSLLVPILIAFFSA"
     gene            1273..2925
                     /gene="hcp"
                     /locus_tag="RN951_001036"
                     /gene_synonym="priS"
     CDS             1273..2925
                     /gene="hcp"
                     /locus_tag="RN951_001036"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HDX2526069.1"
                     /translation="MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQG
                     LSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQC
                     LAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLK
                     GAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSIL
                     DAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLP
                     AHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRS
                     IVGWPGVRHLDGDDFSAVITQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVS
                     REKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLP
                     RLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVK
                     NIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA"
     gene            2937..3905
                     /gene="hcr"
                     /locus_tag="RN951_001037"
     CDS             2937..3905
                     /gene="hcr"
                     /locus_tag="RN951_001037"
                     /EC_number="1.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidoreductase"
                     /protein_id="HDX2526070.1"
                     /translation="MTMPTNQCPWRMQVHHITQETPDVWTISLICHDYYPYRAGQYAL
                     VSVRNSAETLRAYTISSTPGVSEYITLTVRRIDDGVGSQWLTRDVKRGDYLWLSDAMG
                     EFTCDDKAEDKFLLLAAGCGVTPIMSMRRWLAKNRPQADVRVIYNVRTPQDVIFADEW
                     RNYPVTLVAENNVTEGFIAGRLTRELLAGVPDLASRTVMTCGPAPYMDWVEQEVKALG
                     VTRFFKEKFFTPVAEAATSGLKFTKLQPAREFYAPVGTTLLEALESNNVPVVAACRAG
                     VCGCCKTKVVSGEYTVSSTMTLIDAEIAEGYVLACSCHPQGDLVLA"
     gene            4038..5756
                     /gene="poxB"
                     /locus_tag="RN951_001038"
     CDS             4038..5756
                     /gene="poxB"
                     /locus_tag="RN951_001038"
                     /EC_number="1.2.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone-dependent pyruvate dehydrogenase"
                     /protein_id="HDX2526071.1"
                     /translation="MKQTVAAYIAKTLESAGVKRIWGVTGDSLNGLSDSLNRMGTIEW
                     MSTRHEEVAAFAAGAEAQLSGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAAHI
                     PSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVLNRGVSVVVLP
                     GDVALKPAPEGATMHWYHAPQPVVTPEEEELRKLAQLLRYSSNIALMCGSGCAGAHKE
                     LVEFAGKIKAPIVHALRGKEHVEYDNPYDVGMTGLIGFSSGFHTMMNADTLVLLGTQF
                     PYRAFYPTDAKIIQIDINPASIGAHSKVDMALVGDIKSTLRALLPLVEEKADRKFLDK
                     ALEDYRDARKGLDDLAKPSEKAIHPQYLAQQISHFAADDAIFTCDVGTPTVWAARYLK
                     MNGKRRLLGSFNHGSMANAMPQALGAQATEPERQVVAMCGDGGFSMLMGDFLSVVQMK
                     LPVKIVVFNNSVLGFVAMEMKAGGYLTDGTELHDTNFARIAEACGITGIRVEKASEVD
                     EALQRAFSIDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYMLRAIISGRGDEVIELA
                     KTNWLR"
     gene            5793..6794
                     /gene="ltaE"
                     /locus_tag="RN951_001039"
     CDS             5793..6794
                     /gene="ltaE"
                     /locus_tag="RN951_001039"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HDX2526072.1"
                     /translation="MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAA
                     ELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQP
                     IDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRERN
                     LALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAI
                     RWRKMTGGGMRQSGILAAAGIYALKNNVARLQEDHDNAAWMAEQLREAGADVMRQDTN
                     MLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSREQLAEVAAHWRAFLAR"
     gene            6805..8235
                     /locus_tag="RN951_001040"
     CDS             6805..8235
                     /locus_tag="RN951_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415390.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2867 domain-containing protein"
                     /protein_id="HDX2526073.1"
                     /translation="MPQRILVLGASGYIGQHLVRTLSQQGHQILAAARHVDRLAKLQL
                     ANVSCHKVDLSWPDNLPALLQDIDTVYFLVHSMGEGGDFIAQERQVALNVRDALREVP
                     VKQLIFLSSLQAPPHEQSDHLRARQATADILREANVPVTELRAGIIVGAGSAAFEVMR
                     DMVYNLPVLTPPRWVRSRTTPIALENLLHYLVALLDHPASEHRIFEAAGPEVLSYQQQ
                     FEHFMAVSGKRRWLIPIPLPTRWISVWFLNVITSVPPTTARALIQGLKHDLLADDTAL
                     RALIPQRLIAFDDAVRSTLKEEEKLVNSSDWGYDAQAFARWRPEYGYFAKQAGFTVKT
                     SASLAALWQVVNQIGGKERYFFGNILWQTRALMDRAIGHKLAKGRPEREYLQTGDAVD
                     SWKVIVVEPEKQLTLLFGMKAPGLGRLCFSLEDKGDYRTIDVRAFWHPHGMPGLFYWL
                     LMIPAHLFIFRGMAKQIARLAEQSTD"
     gene            8334..9347
                     /locus_tag="RN951_001041"
     CDS             8334..9347
                     /locus_tag="RN951_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415389.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDX2526074.1"
                     /translation="MKVLVTGATSGLGRNAVEFLCQKGISVRATGRNEAMGKLLEKMG
                     AEFVPADLTELVSSQAKVMLAGIDTLWHCSSFTSPWGTQQAFDLANVRATRRLGEWAV
                     AWGVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAASEEVINMLSQANPQ
                     TRFTILRPQSLFGPHDKVFIPRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLA
                     SQEACDKLPSGRVYNITNGEHRTLRSIVQKLIDELNIDCRIRSVPYPMLDMIARSMER
                     LGRKSAKEPPLTHYGVSKLNFDFTLDITRAQEELGYQPVITLDEGIEKTAAWLRDHGK
                     LPR"
     gene            complement(9344..10174)
                     /gene="amiD"
                     /locus_tag="RN951_001042"
     CDS             complement(9344..10174)
                     /gene="amiD"
                     /locus_tag="RN951_001042"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiD"
                     /protein_id="HDX2526075.1"
                     /translation="MRRFFWLVAAALLLAGCAGEKGIVEKEGYQLDTRRQAQAAYPRI
                     KVLVIHYTADDFDSSLATLTDKQVSSHYLVPAVPPRYNGKPRIWQLVPEQELAWHAGI
                     SAWRGATRLNDTSIGIELENRGWQKSAGVKYFAPFEPAQIQALIPLAKDIIARYHIKP
                     ENVVAHADIAPQRKDDPGPLFPWQQLAQQGIGAWPDAQRVNFYLAGRAPHTPVDTASL
                     LELLARYGYDVKPDMTPREQRRVIMAFQMHFRPTLYNGEADAETQAIAEALLEKYGQD
                     "
     gene            complement(10171..10494)
                     /locus_tag="RN951_001043"
     CDS             complement(10171..10494)
                     /locus_tag="RN951_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HDX2526076.1"
                     /translation="MQFSTTPTLEGQTIVEYCGVVTGEAILGANIFRDFFAGIRDIVG
                     GRSGAYEKELRKAREIAFEELGSQARALGADAVVGIDIDYETVGQNGSMLMVSVSGTA
                     VKTRR"
     gene            10620..11135
                     /locus_tag="RN951_001044"
     CDS             10620..11135
                     /locus_tag="RN951_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDX2526077.1"
                     /translation="MRYSKLTMLIPCALLLSACTTVTPAYKDNGTRSGPCVEGGPDNV
                     AQQFYDYRILHRSNDITALRPYLSDKLATLLSDASRDNNHRELLTNDPFSSRTTLPDS
                     AHVASASTIPNRDARNIPLRVDLKQGDQGWQDEVLMIQEGQCWVIDDVRYLGGSVHAT
                     AGTLRQSIENR"
     gene            11353..12081
                     /gene="artP"
                     /locus_tag="RN951_001045"
     CDS             11353..12081
                     /gene="artP"
                     /locus_tag="RN951_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter ATP-binding protein
                     ArtP"
                     /protein_id="HDX2526078.1"
                     /translation="MSIQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSL
                     LRVLNLLEMPRSGTLNIAGNHFDFTKTPSDKAIRDLRRNVGMVFQQYNLWPHLTVQQN
                     LIEAPCRVLGLSKDQALARAEKLLERLRLKPYSDRYPLHLSGGQQQRVAIARALMMEP
                     QVLLFDEPTAALDPEITAQIVSIIRELAETNITQVIVTHEVEVARKTASRVVYMENGH
                     IVEQGDASCFTEPQTEAFKNYLSH"
     gene            12099..12830
                     /gene="artJ"
                     /locus_tag="RN951_001046"
     CDS             12099..12830
                     /gene="artJ"
                     /locus_tag="RN951_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter substrate-binding
                     protein"
                     /protein_id="HDX2526079.1"
                     /translation="MKKVLIAALIAGFSLSATAAETIRFATEASYPPFESIDANNQIV
                     GFDVDLAQALCKEIDATCTFSNQAFDSLIPSLKFRRVEAVMAGMDITPEREKQVLFTT
                     PYYDNSALFVGQQGKYTSVDQLKGKKVGVQNGTTHQKFIMDKHPEITTVPYDSYQNAK
                     LDLQNGRIDGVFGDTAVVTEWLKDNPKLAAVGDKVTDKDYFGTGLGIAVRQGNTELQQ
                     KLNTALEKVKKDGTYETIYNKWFQK"
     gene            12837..13553
                     /gene="artQ"
                     /locus_tag="RN951_001047"
     CDS             12837..13553
                     /gene="artQ"
                     /locus_tag="RN951_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtQ"
                     /protein_id="HDX2526080.1"
                     /translation="MNEFFPLASAAGMTVGLAVCALIVGLALAMFFAVWESAKWRPVA
                     WAGSALVTILRGLPEILVVLFIYFGSSQLLLTLSDGFTINLGFVQIPVQMDIENFDVS
                     PFLCGVIALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRH
                     ALPGLGNQWLVLLKDTALVSLISVNDLMLQTKSIATRTQEPFTWYIVAAAIYLVITLL
                     SQYILKRIDLRATRFERRPS"
     gene            13553..14221
                     /gene="artM"
                     /locus_tag="RN951_001048"
     CDS             13553..14221
                     /gene="artM"
                     /locus_tag="RN951_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtM"
                     /protein_id="HDX2526081.1"
                     /translation="MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVL
                     VWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEYPALWHLLSEPWLCALIALSLNS
                     AAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFK
                     STSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERKALAF
                     ERRN"
     gene            14512..15243
                     /gene="artJ"
                     /locus_tag="RN951_001049"
     CDS             14512..15243
                     /gene="artJ"
                     /locus_tag="RN951_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein ArtJ"
                     /protein_id="HDX2526082.1"
                     /translation="MKKLVLAALLASFTFGASAAEKINFGISATYPPFESIGANNEIV
                     GFDIDLAKALCKQMQAECTFTNHAFDSLIPSLKFRKYDAVISGMDITPERSKQVSFTT
                     PYYENSAVVIAKKDTYKTFADLKGKRIGMENGTTHQKYIQDQHPEVKTVSYDSYQNAF
                     IDLKNGRIDGVFGDTAVVNEWLKTNPQLGVATEKVTDPQYFGTGLGIAVRPDNKALLE
                     KLNNALAAIKADGTYQKISDQWFPQ"
     gene            complement(15442..16569)
                     /gene="rlmC"
                     /locus_tag="RN951_001050"
     CDS             complement(15442..16569)
                     /gene="rlmC"
                     /locus_tag="RN951_001050"
                     /EC_number="2.1.1.189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(747)-C(5))-methyltransferase
                     RlmC"
                     /protein_id="HDX2526083.1"
                     /translation="MQCALYDAGRCRSCQWIMQPIPEQLSAKTADLKNLLADFPVEEW
                     CAPVSGPEQGFRNKAKMVVSGSVEKPLLGMLHRDGTPEDLCDCPLYPASFAPVFAALK
                     PFIARAGLTPYNVARKRGELKYILLTESQSDGGMMLRFVLRSDTKLAQLRKALPWLHE
                     QLPQLKVITVNIQPVHMAIMEGETEIYLTEQQALAERFNDVPLWIRPQSFFQTNPAVA
                     SQLYATARDWVRQLPVKHMWDLFCGVGGFGLHCATPDMQLTGIEIASEAIACAKQSAA
                     ELGLTRLQFQALDSTQFATAQGDVPELVLVNPPRRGIGKPLCDYLSTMAPRFIIYSSC
                     NAQTMAKDIRELPGFRIERVQLFDMFPHTAHYEVLTLLVKQ"
     gene            complement(16610..17098)
                     /locus_tag="RN951_001051"
     CDS             complement(16610..17098)
                     /locus_tag="RN951_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjO family protein"
                     /protein_id="HDX2526084.1"
                     /translation="MEDETLGFFKKTSSSHARLNVPALVQVAALAIIMIRGLDVLMIF
                     NTLGVRGIGEFIHRSVQTWSLTLVFLSSLVLVFIEIWCAFSLVKGRRWARWLYLLTQI
                     TAASYLWAASLGYGYPELFSIPGESKREIFHSLMLQKLPDMLILMLLFVPSTSRRFFQ
                     LQ"
     gene            complement(17158..18003)
                     /gene="potI"
                     /locus_tag="RN951_001052"
     CDS             complement(17158..18003)
                     /gene="potI"
                     /locus_tag="RN951_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotI"
                     /protein_id="HDX2526085.1"
                     /translation="MNNLPVVRSPWRIVILLLGFTFLYAPMLMLVIYSFNSSKLVTVW
                     AGWSTRWYGELLRDDAMMSAVGLSLTIAACAATAAAILGTIAAVVLVRFGRFRGSNGF
                     AFMITAPLVMPDVITGLSLLLLFVALAHAIGWPADRGMLTIWLAHVTFCTAYVAVVIS
                     SRLRELDRSIEEAAMDLGATPLKVFFVITLPMIMPAIISGWLLAFTLSLDDLVIASFV
                     SGPGATTLPMLVFSSVRMGVNPEINALATLILGAVGIVGFIAWYLMARAEKQRIRDIQ
                     RARRG"
     gene            complement(18000..18953)
                     /gene="potH"
                     /locus_tag="RN951_001053"
     CDS             complement(18000..18953)
                     /gene="potH"
                     /locus_tag="RN951_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotH"
                     /protein_id="HDX2526086.1"
                     /translation="MSTLEPAAQSKPPGGFKLWLSQLQMKHGRKLVIALPYIWLILLF
                     LLPFLIVFKISLAEMARAIPPYTELMEWADGQLSITLNLGNFLQLTDDPLYFDAYLQS
                     LQVAAISTFCCLLIGYPLAWAVAHSKPSTRNILLLLVILPSWTSFLIRVYAWMGILKN
                     NGVLNNFLLWLGVIDQPLTILHTNLAVYIGIVYAYVPFMVLPIYTALIRIDYSLVEAA
                     LDLGARPLKTFFTVIVPLTKGGIIAGSMLVFIPAVGEFVIPELLGGPDSIMIGRVLWQ
                     EFFNNRDWPVASAVAIIMLLLLIVPIMWFHKHQQKSVGEHG"
     gene            complement(18963..20096)
                     /gene="potG"
                     /locus_tag="RN951_001054"
     CDS             complement(18963..20096)
                     /gene="potG"
                     /locus_tag="RN951_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter ATP-binding subunit
                     PotG"
                     /protein_id="HDX2526087.1"
                     /translation="MNDAIPRPQAKTRKALTPLLEIRNLTKSYDGQHAVDDVSLTIYK
                     GEIFALLGASGCGKSTLLRMLAGFEQPSAGQIMLDGVDLSQVPPYLRPINMMFQSYAL
                     FPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVAL
                     ARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAG
                     RIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIGSVNVFEGVLKERQEDGLVLDSPGLV
                     HPLKVDADASVVDNVPVHVALRPEKIMLCEEPPANGCNFAVGEVIHIAYLGDLSVYHV
                     RLKSGQMISAQLQNAHRHRKGLPTWGDEVRLCWEVDSCVVLTV"
     gene            complement(20191..21303)
                     /gene="potF"
                     /locus_tag="RN951_001055"
     CDS             complement(20191..21303)
                     /gene="potF"
                     /locus_tag="RN951_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotF"
                     /protein_id="HDX2526088.1"
                     /translation="MTALNKKWLSGLVAGALMAVSVGTLAAEQKTLHIYNWSDYIAPD
                     TVANFEKETGIKVVYDVFDSNEVLEGKLMAGSTGFDLVVPSASFLERQLTAGVFQPLD
                     KSKLPEWKNLDPELLKLVAKHDPDNKFAMPYMWATTGIGYNVDKVKAVLGENAPVDSW
                     DLILKPENLEKLKSCGVSFLDAPEEVFATVLNYLGKDPNSTKADDYTGPATDLLLKLR
                     PNIRYFHSSQYINDLANGDICVAIGWAGDVWQASNRAKEAKNGVNVSFSIPKEGAMAF
                     FDVFAMPADAKNKDEAYQFLNYLLRPDVVAHISDHVFYANANKAATPLVSAEVRENPG
                     IYPPADVRAKLFTLKVQDPKIDRVRTRAWTKVKSGK"
     gene            complement(21654..22130)
                     /locus_tag="RN951_001056"
     CDS             complement(21654..22130)
                     /locus_tag="RN951_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjN domain-containing protein"
                     /protein_id="HDX2526089.1"
                     /translation="MTSLVVPGLDTLRQWLDDLGMSFFECDNCQALHLPHMQNFDGVF
                     DAKIDLIDNTILFSAMAEVRPSAVLPLAADLSAINASSLTVKAFLDMQDDNLPKLVVC
                     QSLSVMQGVTYEQFAWFVRQSEEQISMVILEANAHQLLLPTDDEGQNNVTENYFLH"
     gene            complement(22218..23120)
                     /gene="rimK"
                     /locus_tag="RN951_001057"
     CDS             complement(22218..23120)
                     /gene="rimK"
                     /locus_tag="RN951_001057"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6--L-glutamate ligase"
                     /protein_id="HDX2526090.1"
                     /translation="MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPA
                     ASSIHYKGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLR
                     SMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAA
                     ESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGG
                     AASVASITPQEREIAIKAARTMALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGI
                     DIAGKMIRWIERHATTEYCLKTGG"
     gene            complement(23181..23903)
                     /gene="nfsA"
                     /locus_tag="RN951_001058"
     CDS             complement(23181..23903)
                     /gene="nfsA"
                     /locus_tag="RN951_001058"
                     /EC_number="1.5.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase NfsA"
                     /protein_id="HDX2526091.1"
                     /translation="MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQ
                     CSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFCADFNRHLQICPDAQLGLAEQLL
                     LGVVDTAMMAQNALIAAESLGLGGVYIGGLRNNIEAVTKLLKLPQHVLPLFGLYLGWP
                     ADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTRGSNNRRDTWSDHIRR
                     TIIKESRPFILDYLHKQGWATR"
     gene            complement(23887..24174)
                     /locus_tag="RN951_001059"
     CDS             complement(23887..24174)
                     /locus_tag="RN951_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1418 family protein"
                     /protein_id="HDX2526092.1"
                     /translation="MRAIGKLPKGVLILEFIGMMLLAVALLSVSDSLSLPEPFSRPEV
                     QILMIFLGVLLMLPAAVVVILQVAKRLAPQLMNRPPQYSRSEREKDNDANH"
     gene            24334..24591
                     /gene="grxA"
                     /locus_tag="RN951_001060"
     CDS             24334..24591
                     /gene="grxA"
                     /locus_tag="RN951_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 1"
                     /protein_id="HDX2526093.1"
                     /translation="MQTVIFGRSGCPYCVRAKDLAEKLSNERDDFQYQYVDIRAEGIT
                     KEDLQQKAGKPVETVPQIFVDQQHIGGYTDFAAWVKENLDA"
     gene            complement(24621..24998)
                     /locus_tag="RN951_001061"
     CDS             complement(24621..24998)
                     /locus_tag="RN951_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YbjM"
                     /protein_id="HDX2526094.1"
                     /translation="MKHKQRWAGAICCFVLFIVVCLFLATHMKGAFRAAGHPEIGLLF
                     FILPGAVASFFSQRREVLKPLFGAMLAAPCSMLIMRLFFSPTRSFWQELAWLLSAVFW
                     CALGALCFLFISSLFKPQHRKNQ"
     gene            25268..26953
                     /locus_tag="RN951_001062"
     CDS             25268..26953
                     /locus_tag="RN951_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate:alanine antiporter"
                     /protein_id="HDX2526095.1"
                     /translation="MNINVAELLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVL
                     VVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGS
                     ALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGMESRQLSLALDNLS
                     LGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAY
                     RVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYP
                     DAHARLDPSFRNGKEVFDRDLLDMRIVTEEVVVKNHNAVGKRLAQLKLTDHGCFLNRV
                     IRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFVI
                     GLMIGMITFQFSTFSFGMGNAAGLLFAGIMLGFMRANHPTFGYIPQGALSMVKEFGLM
                     VFMAGVGLSAGSGINNGLGAIGGQMLIAGLIVSLVPVVICFLFGAYVLRMNRALLFGA
                     MMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTIIVMVWPGLG"
     gene            complement(27128..27664)
                     /gene="rcdA"
                     /locus_tag="RN951_001063"
     CDS             complement(27128..27664)
                     /gene="rcdA"
                     /locus_tag="RN951_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator RcdA"
                     /protein_id="HDX2526096.1"
                     /translation="MRRANDPQRREKIIQATLEAVKLYGIHAVTHRKIATLAGVPLGS
                     MTYYFSGIDELLLEAFSSFTEIMSRQYQAFFSDVSDAPGACQAITDMIYSSQVATPDN
                     MELMYQLYALASRKPLLKTVMQNWMQRSQQTLEQWFEPGTARALDAFIEGMTLHFVTD
                     RKPLSREEILRMVERVAG"
     gene            27748..28956
                     /locus_tag="RN951_001064"
     CDS             27748..28956
                     /locus_tag="RN951_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2526097.1"
                     /translation="MTVNSSRNALKRRTWALFMFFFLPGLLMASWATRTPAIRDILSV
                     SIAEMGGVLFGLSIGSMSGILCSAWLVKRFGTRNVILVTMSCALIGMMILSLALWLTS
                     PLLFAVGLGVFGASFGSAEVAINVEGAAVEREMNKTVLPMMHGFYSLGTLAGAGVGMA
                     LTAFGVPATVHILLAALVGIAPIYIAIQAIPDGTGKNAADGTQHGEKGVPFYRDIQLL
                     LIGVVVLAMAFAEGSANDWLPLLMVDGHGFSPTSGSLIYAGFTLGMTVGRFTGGWFID
                     RYSRVAVVRASALMGALGIGLIIFVDSAWVAGVSVVLWGLGASLGFPLTISAASDTGP
                     DAPTRVSVVATTGYLAFLVGPPLLGYLGEHYGLRSAMLVVLALVILAAIVAKAVAKPD
                     TKTQTAMENS"
     gene            28956..29771
                     /gene="ybjI"
                     /locus_tag="RN951_001065"
     CDS             28956..29771
                     /gene="ybjI"
                     /locus_tag="RN951_001065"
                     /EC_number="3.1.3.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415365.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(5-phospho-D-ribitylamino)uracil
                     phosphatase"
                     /protein_id="HDX2526098.1"
                     /translation="MSIKLIAVDMDGTFLSDQKTYNRERFMAQYQQMKAQGIRFVVAS
                     GNQYYQLISFFPEIANEIAFVAENGGWVVSEGKDVFNGELSKDAFATVVEHLLTRPEV
                     EIIACGKNSAYTLKKYDDAMKTVAEMYYHRLEYVDNFDNLEDIFFKFGLNLSDELIPQ
                     VQKALHEAIGDIMVSVHTGNGSIDLIIPGVHKANGLRQLQKLWGIDDSEVVVFGDGGN
                     DIEMLRQAGFSFAMENAGSAVVAAAKYRAGSNNREGVLDVIDKVLKHEAPFDQ"
     gene            29857..30141
                     /locus_tag="RN951_001066"
     CDS             29857..30141
                     /locus_tag="RN951_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526099.1"
                     /translation="MIMKNCLLLGALLMGFTGVAMAQSVTVDVPSGYKVVVVPDSVSV
                     PQAVSVATVPQTVYVAPAPAPAYRPHPYVRHLASVGEGMVIEHQIDDHHH"
     gene            complement(30182..31414)
                     /gene="mdfA"
                     /locus_tag="RN951_001067"
     CDS             complement(30182..31414)
                     /gene="mdfA"
                     /locus_tag="RN951_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdfA"
                     /protein_id="HDX2526100.1"
                     /translation="MQNKLASGARLGRQALLFPLCLVLYEFSTYIGNDMIQPGMLAVV
                     EQYQAGIDWVPTSMTAYLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIVTCLAILLA
                     QNIEQFTLLRFLQGISLCFIGAVGYAAIQESFEEAVCIKITALMANVALIAPLLGPLV
                     GAAWIHVLPWEGMFVLFAALAAISFFGLQRAMPETATRIGEKLSLKELGRDYKLVLKN
                     GRFVAGALALGFVSLPLLAWIAQSPIIIITGEQLSSYEYGLLQVPIFGALIAGNLLLA
                     RLTSRRTVRSLIIMGGWPIMIGLLVAAAATVISSHAYLWMTAGLSIYAFGIGLANAGL
                     VRLTLFASDMSKGTVSAAMGMLQMLIFTVGIEISKHAWLNGGNGLFNLFNLVNGILWL
                     SLMVIFLKDKQMGNSHEG"
     gene            31699..32295
                     /gene="ybjG"
                     /locus_tag="RN951_001068"
     CDS             31699..32295
                     /gene="ybjG"
                     /locus_tag="RN951_001068"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDX2526101.1"
                     /translation="MLENLNLSLFSLINATPDSAPWMISLAIFIAKDLITVVPLLAVV
                     LWLWGLTAQRQLVIKIAIALAVSLFVSWTMGHLFPHDRPFVENIGYNFLHHAADDSFP
                     SDHGTVIFTFALAFLCWHRLWSGSLLMVLAVVIAWSRVYLGVHWPLDMLGGLLAGMIG
                     CLSAQIIWQAMGHKLYQRLQSWYRVCFALPIRKGWVRD"
     gene            32353..33111
                     /gene="deoR"
                     /locus_tag="RN951_001069"
     CDS             32353..33111
                     /gene="deoR"
                     /locus_tag="RN951_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor DeoR"
                     /protein_id="HDX2526102.1"
                     /translation="METRREERIGQLLQELKRSDKLHLKDAAALLGVSEMTIRRDLNN
                     HSAPVVLLGGYIVLEPRSASHYLLSDQKSRLVEEKRRAAKLAATLVEPDQTLFFDCGT
                     TTPWIIEAIDNEIPFTAVCYSLNTFLALKEKPHCRAFLCGGEFHASNAIFKPIDFQQT
                     LNNFCPDIAFYSAAGVHVSKGATCFNLEELPVKHWAMSMAQKHVLVVDHSKFGKVRPA
                     RMGDLKRFDIVVSDCCPEDEYVKYAQTQRIKLMY"
     gene            complement(33158..34360)
                     /gene="dacC"
                     /locus_tag="RN951_001070"
     CDS             complement(33158..34360)
                     /gene="dacC"
                     /locus_tag="RN951_001070"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HDX2526103.1"
                     /translation="MTQYSSLLRGLAAGSAFLFLFAPTAFAAEQTVEAPSVDARAWIL
                     MDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALKADKIKLTDMVTVGKDAWATGN
                     PALRGSSVMFLKPGDQVSVADLNKGVIIQSGNDACIALADYVAGSQESFIGLMNGYAK
                     KLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPEEYAIHKEKEFTFNKIRQP
                     NRNRLLWSSNLNVDGMKTGTTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEK
                     LLTWGFRFFETVTPIKPDATFVTQRVWFGDKSEVNLGAGEAGSVTIPRGQLKNLKASY
                     TLTEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLIVMENVEEGGFFGRVWDFVMMKFH
                     QWFGSWFS"
     gene            34607..35233
                     /gene="gstB"
                     /locus_tag="RN951_001071"
     CDS             34607..35233
                     /gene="gstB"
                     /locus_tag="RN951_001071"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308945.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase GstB"
                     /protein_id="HDX2526104.1"
                     /translation="MITLWGRNNSTNVKKVLLTLEELELPYEQILAGREFGINHDADF
                     LAMNPNGLVPLLRDDESDLILWESNAIVRYLAAQYGQKRLWIDSPARRAEAEKWMDWA
                     NQTLSNAHRGILMGLVRTPPEERDQAAIDASCKECDALFALLDAELAKVKWFSGDEFG
                     VGDIAIAPFIYNLFNVGLTWTPRPNLQRWYQQLTERPAVRKVVMIPVS"
     gene            complement(35230..36345)
                     /gene="yliI"
                     /locus_tag="RN951_001072"
     CDS             complement(35230..36345)
                     /gene="yliI"
                     /locus_tag="RN951_001072"
                     /EC_number="1.1.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose sugar dehydrogenase YliI"
                     /protein_id="HDX2526105.1"
                     /translation="MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLP
                     DNHGMLITLRGGELRHWQAGKGLSAPLSGVPDVWAHGQGGLLDVVLAPDFAQSRRIWL
                     SYSEVGDDGKAGTAVGYGRLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRLVFDGKGYL
                     FIALGENNQRPTAQDLDKLQGKLVRLTDQGEIPDDNPFIKESGARAEIWSYGIRNPQG
                     MAMNPWSNALWLNEHGPRGGDEINIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAG
                     TEQPVFYWKDSPAVSGMAFYNSDKFPQWQQKLFIGALKDKDVIVMSVNGDKVTEDGRI
                     LTDRGQRIRDVRTGPDGYLYVLTDESSGELLKVSPRN"
     gene            complement(36456..36839)
                     /gene="bssR"
                     /locus_tag="RN951_001073"
     CDS             complement(36456..36839)
                     /gene="bssR"
                     /locus_tag="RN951_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssR"
                     /protein_id="HDX2526106.1"
                     /translation="MFVDRQRIDLLNRLIDARVDLAAYVQLRKAKGYMSVSESNHLRD
                     NFFKLNRELHDKSLRLNLHLDQEEWSALHHAEEALATAAVCLMSGHHDCPTVITVNAD
                     KLENCLMSLTLSIQSLQKHAMLEKA"
     gene            37052..38377
                     /gene="rimO"
                     /locus_tag="RN951_001074"
     CDS             37052..38377
                     /gene="rimO"
                     /locus_tag="RN951_001074"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HDX2526107.1"
                     /translation="MSKVTPQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPSYDD
                     ADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITG
                     PHSYEQVLEHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIP
                     SMRGDLVSRPIGEVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPVKTS
                     MVSLCEQLSKLGIWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMK
                     RPGSVDRQLARIKQWREICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCF
                     KYSPVEGADANALPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIIDEVDE
                     EGAIGRSMADAPEIDGAVYLNGETNVKPGDILRVKVEHADEYDLWGSRV"
     gene            complement(38424..39752)
                     /locus_tag="RN951_001075"
     CDS             complement(38424..39752)
                     /locus_tag="RN951_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDX2526108.1"
                     /translation="MSRINKFVLTVSLLIFIMISAVACGIYTQMVKERVYSLKQSVID
                     TAFAVANIAEYRRSVAIDLINTLNPTEEQLLVGLRTAYADSVSPSYLYDVGPYLISSD
                     ECIQVKEFEKNYCADIMQVVKYRHVKNTGFISFDGKTFVYYLYPVTHNRSLIFLLGLE
                     RFSLLSKSLAMDSENLMFSLFKNGKPVTGDEYNAKNAIFTVSEAMEHFAYLPTGLYVF
                     AYKKDVYLRVCTLIIFFAALVAVISGASCLYLVRRVINRGIVEKEAIINNHFERVLDG
                     GLFFSAADVKKLYSMYNSAFLDDLTKAMGRKSFDEDLKALPEKGGYLCLFDVDKFKNI
                     NDTFGHLLGDEVLMKVVKILKSQIPVDKGKVYRFGGDEFAVIYTGGTLEELLSILKEI
                     VHFQVGSINLSTSIGVAHSNECPTVERLKMLADERLYKSKKNGRAQISWQ"
     gene            complement(39760..42108)
                     /locus_tag="RN951_001076"
     CDS             complement(39760..42108)
                     /locus_tag="RN951_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDX2526109.1"
                     /translation="MLSLYEKIKIRLIILFLLAALSFIGLFFIINYQLVSERAVKRAD
                     SRFELIQKNVGYFFKDIERSALTLKDSLYLLKNTEEIQRAVILKMEMMPFLDSVGLVL
                     DDNKYYLFSRRANDKIVVYHQEQVNGPLVDESGRVIFADFNPSKRPWSVASDDSNNSW
                     NPAYNCFDRPGKKCISFTLHINGKDHDLLAVDKIHVDLNWRYLNEYLDQISANDEVLF
                     LKQGHEIIAKNQLAREKLIIYNSEDNYNIIDSVDTEYIEKTSAVPNNALFEIYFYYPG
                     GNLLNASDKLFYLPFAFIIIVLLVVYLMTTRVFRRQFSEMTELVNTLAFLPDSTDQIE
                     ALKIREGDAKEIISIKNSIAEMKDAEIERSNKLLSLISYDQESGFIKNMAIIESNNNQ
                     YLAVGIIKLCGLEAVEAVFGVDERNKIVRKLCQRIAEKYAQCCDIVTFNADLYLLLCR
                     ENVQTFTRKIAMVNDFDSSFGYRNLRIHKSAICEPLQGENAWSYAEKLKLAISSIRDH
                     MFSEFIFCDDAKLNEIEENIWIARNIRHAMEIGELFLVYQPIVDINTRAILGAEALCR
                     WVSAERGIISPLKFITIAEDIGFINELGYQIIKTAMGEFRHFSQRASLKDDFLLHINV
                     SPWQLNEPHFHERFTTIMKENGLKANSLCVEITETVIERINEHFYLNIEQLRKQGVRI
                     SIDDFGTGLSNLKRFYEINPDSIKVDSQFTGDIFGTAGKIVRIIFDLARYNRIPVIAE
                     GVESEDVARELIKLGCVQAQGYLYQKPMPFSAWDKSGKLVKE"
     gene            complement(42286..43197)
                     /gene="gsiD"
                     /locus_tag="RN951_001077"
     CDS             complement(42286..43197)
                     /gene="gsiD"
                     /locus_tag="RN951_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiD"
                     /protein_id="HDX2526110.1"
                     /translation="MRLFNWRRQAVLNAMPLVKPDQVRTPWHEFWRRFRRQHMAMTAA
                     LFVILLIVVAIFARWIAPYDAENYFDYDNLNNGPSLQHWFGVDSLGRDIFSRVLVGAQ
                     ISLAAGVFAVFIGAAIGTLLGLLAGYYEGWWDRLIMRICDVLFAFPGILLAIAVVAVL
                     GSGIANVIIAVAIFSIPAFARLVRGNTLVLKQQTFIESARSIGASDMTVLLRHILPGT
                     VSSIVVFFTMRIGTSIISAASLSFLGLGAQPPTPEWGAMLNEARADMVIAPHVAVFPA
                     LAIFLTVLAFNLLGDGLRDALDPKIKG"
     gene            complement(43200..44120)
                     /gene="gsiC"
                     /locus_tag="RN951_001078"
     CDS             complement(43200..44120)
                     /gene="gsiC"
                     /locus_tag="RN951_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiC"
                     /protein_id="HDX2526111.1"
                     /translation="MLNYVIKRLLGLIPTLFIVSVLVFLFVHMLPGDPARLIAGPEAD
                     AQVIELVRQQLGLDQPLYHQFWHYISNAVQGDFGLSMVSRRPVADEIASRFMPTLWLT
                     ITSMVWAVIFGMAAGIIAAVWRNRWPDRLSMTIAVSGISFPAFALGMLLIQVFSVELG
                     WLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVDVLSEDYMRTARAKGVSETWV
                     VLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQA
                     EILLFSLEFILINLVVDVLYAAINPAIRYK"
     gene            complement(44138..45676)
                     /gene="gsiB"
                     /locus_tag="RN951_001079"
     CDS             complement(44138..45676)
                     /gene="gsiB"
                     /locus_tag="RN951_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter substrate-binding
                     protein GsiB"
                     /protein_id="HDX2526112.1"
                     /translation="MARAVHRSGLVALGIATALMASCAFAAKDVVVAVGSNFTTLDPY
                     DANDTLSQAVAKSFYQGLFGLDKEMKLKNVLAESYTVSDDGITYTVKLREGIKFQDGT
                     DFNAAAVKANLDRASDPANHLKRYNLYKNIAKTEAIDPTTVKITLKQPFSAFINILAH
                     PATAMISPAALEKYGKEIGFYPVGTGPYELDTWNQTDFVKVKKFAGYWQPGLPKLDSI
                     TWRPVADNNTRAAMLQTGEAQFAFPIPYEQATLLEKNKNIELMASPSIMQRYISMNVT
                     QKPFDNPKVREALNYAINRPALVKVAFAGYATPATGVVPPSIAYAQSYKPWPYDPVKA
                     RELLKEAGYPNGFSTTLWSSHNHSTAQKVLQFTQQQLAQVGIKAQVTAMDAGQRAAEV
                     EGKGQKESGVRMFYTGWSASTGEADWALSPLFASQNWPPTLFNTAFYSNKQVDDFLAQ
                     ALKTNDPAEKTRLYKAAQDIIWQESPWIPLVVEKLVSAHSKNLTGFWIMPDTGFSFED
                     ADLQ"
     gene            complement(45696..47567)
                     /gene="gsiA"
                     /locus_tag="RN951_001080"
     CDS             complement(45696..47567)
                     /gene="gsiA"
                     /locus_tag="RN951_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415350.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter ATP-binding protein
                     GsiA"
                     /protein_id="HDX2526113.1"
                     /translation="MPHSDELDAGNVLAVENLNIAFMQDQQKIAAVRNLSFSLQRGET
                     LAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLQRRSREVIELSEQNAAQMRHVR
                     GADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQNASREEAMVEAKRMLDQVRIPEAQT
                     ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEM
                     SMGVIFITHDMGVVAEIADRVLVMYQGEAVETGTVEQIFHAPQHPYTRALLAAVPQLG
                     AMKGLDYPRRFPLISLEHPAKQAPPIEQKTVVDGEPVLRVRNLVTRFPLRSGLLNRVT
                     REVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLS
                     PGKLQALRRDIQFIFQDPYASLDPRQTIGDSIIEPLRVHGLLPGKDAAARVAWLLERV
                     GLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLD
                     LQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYTRKLLAA
                     VPVAEPSRQRPQRVLLSDDLPSNIHLRGEEVAAVSLQCVGPGHYVAQPQSEYAFMRR"
     gene            complement(47554..48519)
                     /gene="iaaA"
                     /locus_tag="RN951_001081"
     CDS             complement(47554..48519)
                     /gene="iaaA"
                     /locus_tag="RN951_001081"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HDX2526114.1"
                     /translation="MGKAVIAIHGGAGAISRAQMSLQQELRYIEALSAIVETGQKMLE
                     AGESALDVVTEAVRLLEECPLFNAGIGAVFTRDETHELDACVMDGNTLKAGAVAGVSH
                     LRNPVLAARLVMEQSPHVMMIGEGAENFAFARGMERVSPEIFSTPLRYEQLLAARKEG
                     ATVLDHSGAPLDEKQKMGTVGAVALDLDGNLAAATSTGGMTNKLPGRVGDSPLVGAGC
                     YANNASVAVSCTGTGEVFIRALAAYDIAALMDYGGLSLAEACERVVMEKLPALGGSGG
                     LIAIDHEGNVALPFNTEGMYRAWGYAGDTPTTGIYREKGDTVATQ"
     gene            48723..49958
                     /gene="moeA"
                     /locus_tag="RN951_001082"
     CDS             48723..49958
                     /gene="moeA"
                     /locus_tag="RN951_001082"
                     /EC_number="2.10.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HDX2526115.1"
                     /translation="MEFTTGLMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDV
                     VSPLDVPGFDNSAMDGYAVRLADIASGQPLPVAGKSFAGQPYHGEWPAGTCIRIMTGA
                     PVPEGCEAVVMQEQTEQMDNGVRFTAEVRSGQNIRRRGEDISAGAVVFPAGTRLTTAE
                     LPVIASLGIAEVPVIRKVRVALFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGC
                     EVINLGIIRDDPHALRAAFIEADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKL
                     AIKPGKPFAFGKLSNSWFCGLPGNPVSATLTFYQLVQPLLAKLSGNTASGLPARQRVR
                     TASRLKKTPGRLDFQRGVLQRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGN
                     VEVGEWVEVEPFNALFGGL"
     gene            49958..50707
                     /gene="moeB"
                     /locus_tag="RN951_001083"
     CDS             49958..50707
                     /gene="moeB"
                     /locus_tag="RN951_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-synthase adenylyltransferase MoeB"
                     /protein_id="HDX2526116.1"
                     /translation="MAELSDQEMLRYNRQIILRGFDFDGQEALKDSRVLIVGLGGLGC
                     AASQYLASAGVGNLTLLDFDTVSLSNLQRQTLHSDATVGQPKVESARDALTRINPHIA
                     ITPVNALLDDAELAALIAEHDLVLDCTDNVAVRNQLNAGCFAAKVPLVSGAAIRMEGQ
                     ITVFTYQDGEPCYRCLSRLFGENALTCVEAGVMAPLIGVIGSLQAMEAIKMLAGYGKP
                     ASGKIVMYDAMTCQFREMKLMRNPGCEVCGQ"
     gene            complement(50783..51445)
                     /gene="fsa"
                     /locus_tag="RN951_001084"
     CDS             complement(50783..51445)
                     /gene="fsa"
                     /locus_tag="RN951_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415346.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDX2526117.1"
                     /translation="MELYLDTSDVVAVKALSRIFPLAGVTTNPSIIAAGKKPLDVVLP
                     QLHEAMGGQGRLFAQVMATTAEGMVNDALKLRSIIADIVVKVPVTAEGLAAIKMLKAE
                     GIPTLGTAVYGAAQGLLSALAGAEYVAPYVNRIDAQGGSGIQTVTDLHQLLKMHAPQA
                     KVLAASFKTPRQALDCLLAGCESITLPLDVAQQMISYPAVDAAVAKFEQDWQGAFGRT
                     SI"
     gene            51576..52475
                     /locus_tag="RN951_001085"
     CDS             51576..52475
                     /locus_tag="RN951_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415345.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HDX2526118.1"
                     /translation="MIFNIQRYSTHDGPGIRTVVFLKGCSLGCRWCQNPESRARTQDL
                     LYDARLCLEGCELCAKAAPEVIERALNGLLIHREKLTPEHLTALTDCCPTQALTVCGE
                     VKSVEEIMTTVLRDKPFYDRSGGGLTLSGGEPFMQPEMAMALLQASHEAGIHTAVETC
                     LHVPWKYIAPSLPYIDLFLADLKHVADAPFKQWTDGNAARVLDNLKKLAAAGKKIIIR
                     VPLIQGFNADETSVKAITDFAADELHVGEIHFLPYHTLGINKYHLLNLPYDAPEKPLD
                     APELLDFAQQYACQKGLTATLRG"
     gene            52481..54913
                     /locus_tag="RN951_001086"
     CDS             52481..54913
                     /locus_tag="RN951_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HDX2526119.1"
                     /translation="MTTLKLDTLSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHL
                     DKPIPVRRALALAHHLANRTIWIKHDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDL
                     ADRPGAGFAVSEENKRVLHEVCPWWRGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMT
                     SGDAHLAVNFPLLLEKGLDGLREKVAERRSRINLTVLEDLHGEQFLKAIDIVLVAVSE
                     HIERFAALAREMAATETRESRRDELLAMAENCDLIAHQPPQTFWQALQLCYFIQLILQ
                     IESNGHSVSFGRMDQYLYPYYRRDVELNQTLDREHAIEMLHSCWLKLLEVNKIRSGSH
                     SKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLSYAILESCGRLRSTQPNLSVRYHAGM
                     SNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLGIEPQDAYDYAAIGCIETAVGGKW
                     GYRCTGMSFINFARVMLAALEGGHDATSGKVFLPQEKALSAGNFNNFDEVMDAWDTQI
                     RYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAKSIKQGGAKYDWVSGLQVGI
                     ANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQLRQRLINGAPKYGNDDDT
                     VDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISANVPFGAQTMATPDGRK
                     AHTPLAEGASPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQKLNPATLENESDKQK
                     LMILLRTFFEVHKGWHIQYNIVSRETLLDAKKHPDQYRDLVVRVAGYSAFFTALSPDA
                     QDDIIARTEHML"
     gene            55059..55874
                     /gene="ybiV"
                     /locus_tag="RN951_001087"
     CDS             55059..55874
                     /gene="ybiV"
                     /locus_tag="RN951_001087"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase YbiV"
                     /protein_id="HDX2526120.1"
                     /translation="MSVKVIVTDMDGTFLNDAKTYNQPRFMAQYQELKKRGIKFVVAS
                     GNQYYQLISFFPELKDEISFVAENGALVYEHGKQLFHGELTRHESRIVIGELLKDKQL
                     NFVACGLQSAYVSENAPEAFVALMAKHYHRLKPVKDYQEIDDVLFKFSLNLPDEQIPL
                     VIDKLHVALDGIMKPVTSGFGFIDLIIPGLHKANGISRLLKRWDLSPQNVVAIGDSGN
                     DAEMLKMARYSFAMGNAAENIKQIARYATDDNNHEGALNVIQAVLDNTSPFNS"
     gene            56026..57291
                     /locus_tag="RN951_001088"
     CDS             56026..57291
                     /locus_tag="RN951_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1479 domain-containing protein"
                     /protein_id="HDX2526121.1"
                     /translation="MASTFTSDTLPADHKAAIRQMKHALRAQLGDVQQIFNQLSDDIA
                     TRVAEINALKAQGDAVWPVLSYADIKAGHVTAEQREQIKRRGCAVIKGHFPREQALGW
                     DQSMLDYLDRNRFDEVYKGPGDNFFGTLSASRPEIYPIYWSQAQMQARQSEEMANAQS
                     FLNRLWTFESDGKQWFNPDVSVIYPDRIRRRPPGTTSKGLGAHTDSGALERWLLPAYQ
                     RVFANVFNGNLAQYDPWHAAHRTEVEEYTVDNTTKCSVFRTFQGWTALSDMLPGQGLL
                     HVVPIPEAMAYVLLRPLLDDVPEDELCGVAPGRVLPVSEQWHPLLIEALTSIPKLEAG
                     DSVWWHCDVIHSVAPVENQQGWGNVMYIPAAPMCEKNLAYAHKVKAALEKGASPGDFP
                     REDYETNWEGRFTLADLNIHGKRALGMDV"
     gene            complement(57532..59124)
                     /locus_tag="RN951_001089"
     CDS             complement(57532..59124)
                     /locus_tag="RN951_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATPase"
                     /protein_id="HDX2526122.1"
                     /translation="MLVSSNVTMQFGSKPLFENISVKFGGGNRYGLIGANGSGKSTFM
                     KILGGDLEPTLGNVSLDPNERIGKLRQDQFAFEEFTVLDTVIMGHKELWEVKQERDRI
                     YALPEMSEEDGYKVADLEVKYGEMDGYSAEARAGELLLGVGIPVEQHYGPMSEVAPGW
                     KLRVLLAQALFADPDILLLDEPTNNLDIDTIRWLEQVLNERDSTMIIISHDRHFLNMV
                     CTHMADLDYGELRVYPGNYDEYMTAATQARERLLADNAKKKAQIAELQSFVSRFSANA
                     SKSRQATSRARQIDKIKLEEVKASSRQNPFIRFEQDKKLFRNALEVEGLTKGFDNGPL
                     FKNLNLLLEVGEKLAVLGTNGVGKSTLLKTLVGDLQPDSGTVKWSENARIGYYAQDHE
                     YEFENDLTVFEWMSQWKQEGDDEQAVRSILGRLLFSQDDIKKPAKVLSGGEKGRMLFG
                     KLMMQKPNILIMDEPTNHLDMESIESLNMALELYQGTLIFVSHDREFVSSLATRILEI
                     TPERVIDFSGNYEDYLRSKGIE"
     gene            59343..60263
                     /gene="ldtB"
                     /locus_tag="RN951_001090"
     CDS             59343..60263
                     /gene="ldtB"
                     /locus_tag="RN951_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HDX2526123.1"
                     /translation="MNMKLKTLFAAAFAVVGFCSTASAVTYPLPTDGSRLVGQNQVIT
                     IPEGNTQPLEYFAAEYQMGLSNMMEANPGVDTFLPKGGTVLNIPQQLILPDTVHEGIV
                     INSAEMRLYYYPKGTNTVIVLPIGIGQLGKDTPINWTTKVERKKAGPTWTPTAKMHAE
                     YRAAGEPLPAVVPAGPDNPMGLYALYIGRLYAIHGTNANFGIGLRVSHGCVRLRNEDI
                     KFLFEKVPVGTRVQFIDEPVKATTEPDGSRYIEVHNPLSTTEAQFEGQEIVPITLTKS
                     VQTVTGQPDVDQVVLDEAIKNRSGMPVRLN"
     gene            complement(60322..61440)
                     /locus_tag="RN951_001091"
     CDS             complement(60322..61440)
                     /locus_tag="RN951_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion transporter"
                     /protein_id="HDX2526124.1"
                     /translation="MSLPFLRTLQGDRFFQLLILVGIGLSFFVPFAPKSWPAAIDWHT
                     IITLSGLMLLTKGVELSGYFDVLGRKMVRRFATERRLAMFMVLAAALLSTFLTNDVAL
                     FIVVPLTITLKRLCEIPVNRLIIFEALAVNAGSLLTPIGNPQNILIWGRSGLSFAGFI
                     AQMAPLAGAMMLTLLLLCWCCFPGKAMQYHTGVQTPEWKPRLVWSCLGLYIVFLTALE
                     FKQELWGLVIVAAGFALLARRVVLSVDWTLLLVFMAMFIDVHLLTQLPALQGVLGNVS
                     HLSEPGLWLTAIGLSQVISNVPSTILLLNYVPPSLLLVWAVNVGGFGLLPGSLANLIA
                     LRMANDRRIWWRFHLYSIPMLLWAALVGYVLLVILPAN"
     gene            complement(61437..61904)
                     /gene="mntR"
                     /locus_tag="RN951_001092"
     CDS             complement(61437..61904)
                     /gene="mntR"
                     /locus_tag="RN951_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-binding transcriptional regulator
                     MntR"
                     /protein_id="HDX2526125.1"
                     /translation="MSRRAGTPTAKKVTQLVNVEEHVEGFRQVREAHRRELIDDYVEL
                     ISDLIREVGEARQVDMAARLGVSQPTVAKMLKRLATMGLIEMIPWRGVFLTAEGEKLA
                     QESRERHQIVENFLLVLGVSPEIARRDAEGMEHHVSEETLDAFRLFTQKHGAK"
     gene            62090..62218
                     /gene="mntS"
                     /locus_tag="RN951_001093"
     CDS             62090..62218
                     /gene="mntS"
                     /locus_tag="RN951_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganase accumulation protein MntS"
                     /protein_id="HDX2526126.1"
                     /translation="MNEFKRCMRVFSHSPFKVRLMLLSMLCDMVNNKPQQDKPSDK"
     gene            62490..64073
                     /gene="opgE"
                     /locus_tag="RN951_001094"
     CDS             62490..64073
                     /gene="opgE"
                     /locus_tag="RN951_001094"
                     /EC_number="2.7.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HDX2526127.1"
                     /translation="MNLTLKESLVTRSRVFSPWTAFYFLQSLLINLGLGYPFSLLYTA
                     AFTAILLLLWRTLPRVQKVLVGVSSLVAACYFPFAQAYGAPNFNTLLALHSTNMEEST
                     EILTIFPWYSYLVGLFIFALGVIAIRRKKENEKARWNTFDSLCLVFSVATFFVAPVQN
                     LAWGGVFKLKDTGYPVFRFAKDVIVNNNEVIEEQERMAKLSGMKDTWTVTAVKPKYQT
                     YVVVIGESARRDALGAFGGHWDNTPFASSVNGLIFADYIAASGSTQKSLGLTLNRVVD
                     GKPQFQDNFVTLANRAGFQTWWFSNQGQIGEYDTAIASIAKRADEVYFLKEGNFEADK
                     NTKDEALLDMTAQVLAQEHSQPQLIVLHLMGSHPQACDRTQGKYETFVQSKETSCYLY
                     TMTQTDDLLRKLYDQLRNSGSSFSLVYFSDHGLAFKERGKDVQYLAHDDKYQQNFQVP
                     FMVISSDDKAHRVIKARRSANDFLGFFSQWTGIKAKEINIKYPFISEKKAGPIYITNF
                     QLQKVDYNHLGTDIFDPKP"
     gene            complement(64122..64637)
                     /gene="ompX"
                     /locus_tag="RN951_001095"
     CDS             complement(64122..64637)
                     /gene="ompX"
                     /locus_tag="RN951_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpX"
                     /protein_id="HDX2526128.1"
                     /translation="MKKIACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMNKM
                     GGFNLKYRYEEDNSPLGVIGSFTYTEKSRTASSGDYNKNQYYGITAGPAYRINDWASI
                     YGVVGVGYGKFQTTEYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDV
                     GTWIAGVGYRF"
     gene            complement(64690..64755)
                     /locus_tag="RN951_001096"
     CDS             complement(64690..64755)
                     /locus_tag="RN951_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526129.1"
                     /translation="METFCYMKWPVRHHKSRRVSH"
     gene            64990..65877
                     /gene="rhtA"
                     /locus_tag="RN951_001097"
     CDS             64990..65877
                     /gene="rhtA"
                     /locus_tag="RN951_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/homoserine exporter RhtA"
                     /protein_id="HDX2526130.1"
                     /translation="MPGSLRKMPVWLPIVILLVAMASIQGGASLAKSLFPLVGAPGVT
                     ALRLALGTLILIAFFKPWRLRFAKEQRLPLLFYGVSLGGMNYLFYLSIQTVPLGIAVA
                     LEFTGPLAVALFSSRRPVDFVWVVLAVLGLWFLLPLGQDVSHVDLTGCALALGAGACW
                     AIYILSGQRAGAEHGPATVAIGSLIAALIFVPIGALQAGEALWHWSVIPLGLAVAILS
                     TALPYSLEMIALTRLPTRTFGTLMSMEPALAAVSGMIFLGETLTPIQLLALGAIIAAS
                     MGSTLTVRKESKIKELDIN"
BASE COUNT        16138 a        17435 c        16396 g        15925 t
ORIGIN      
        1 cacatccatg tgggctgccc cggccttcag ggaacgcctc ggcgattttg acgccaccaa
       61 catcggtgca gtttgtaatt aaagcgcaag aatatcttta aatgaaaacg aatactctac
      121 tgctccttat gcataacatt tccttttaat tgcaacttta ctcgtccttc cgctttcagt
      181 agtgtgtcat cgcgcatttc gacttcatct ttgcaaggac tgggttttca tgttttctgg
      241 gctgttaatc attctggttc ccctgattgt gggttacctc attccgcttc gccaacaagc
      301 tgcgttaaaa gttattaatc agctattaag ctggatggtt taccttattc tcttttttat
      361 gggtatcagt ctggcgtttc tcgataacct cgccagtaac ctgttggcga ttctgcatta
      421 ttctgccgtc agtattaccg ttattttact gtgtaatatt gccgccctga tgtggctgga
      481 gcgaggcctg ccgtggcgca accaccatca gcaagaaaaa ctcccgtcgc gtattgcgat
      541 ggcgctggag tcgctaaaac tgtgcggcgt agtagtgatt ggttttgcca ttggtctaag
      601 tggactggct ttcttacaac acgcgaccga agccagtgaa tacacgttaa ttttgctact
      661 tttcctcgtt ggtattcagt tgcgcaataa tggcatgacc ttaaagcaga ttgtccttaa
      721 tcgccgggga atgattgtcg ccgtggtggt ggttgtcagt tcattaattg gtggtttaat
      781 taacgccttt attcttgatc tccccatcaa taccgcgctg gcaatggcct ccggtttcgg
      841 ctggtattct ctttccggta ttttattgac cgaatctttt ggtccggtaa tcgggagcgc
      901 ggcgtttttt aatgatctgg cccgtgaact gattgctatt atgttgatcc ctgggctgat
      961 tcgccgcagc cgctctactg cactgggctt atgcggtgcc acatcaatgg atttcaccct
     1021 gcccgttctt caacgtactg gcgggctgga tatggtcccg gcggcaattg ttcacggttt
     1081 tattcttagc ctgttagtgc cgatcctcat cgcctttttc tctgcgtaat acctctctgg
     1141 cggtagatcc ctgccgccaa aattgcgcta aatcaatctc ccttaaagtt gcatgaaaaa
     1201 tcccttttat ccccgcgtta agcgtcttaa ccttaaacat gtatattaaa tataacttta
     1261 aaaggtgtga tcatgttttg tgtgcaatgt gaacaaacta tccgtactcc ggcaggaaac
     1321 ggctgctcat acgcgcaggg gatgtgtggt aaaacggcgg aaacttctga ccttcaggat
     1381 ttactcatcg cggcgctgca agggctttct gcctgggcgg taaaagcgcg tgaatacggc
     1441 atcatcaacc acgatgttga cagcttcgcg ccacgtgcct ttttctcaac cctgaccaac
     1501 gttaacttcg attctccgcg tattgtcggt tacgctcgtg aagcgattgc cctgcgcgag
     1561 gcgctgaaag cgcaatgcct ggctgtagat gccaacgcgc gcgtcgataa cccgatggct
     1621 gacctgcaac tggtgagcga cgatctcggc gagctgcaac gtcaggcagc agaatttacc
     1681 cctaacaaag ataaagcggc gattggcgaa aacattctcg gcctgcgtct gctgtgcctg
     1741 tatggcctga aaggtgcggc ggcctatatg gaacacgcgc atgttctcgg tcaatacgac
     1801 aacgatattt atgcccagta ccataaaatc atggcgtggc tggggacctg gcctgccgat
     1861 atgaacgcgc ttcttgagtg ttcaatggaa atcggccaga tgaacttcaa agtgatgagc
     1921 attctggatg caggcgaaac cggtaaatac ggtcacccga cgccaaccca ggtcaacgtc
     1981 aaagcgacgg cgggtaaatg cattctgatt tccggtcacg atctcaaaga tctctacaac
     2041 ctgctggaac agaccgaagg cacgggcgtt aatgtctaca cccacggcga aatgctgcct
     2101 gcgcatggct acccggagct gcgtaaattc aagcatctgg tcggtaacta cggcagcggc
     2161 tggcagaatc agcaagtgga gttcgctcgt ttccctggcc ccatcgtgat gacctcgaac
     2221 tgcatcatcg acccaaccgt aggcgcttat gacgatcgta tctggacccg cagcattgtt
     2281 ggctggcctg gcgtgcgtca tctggacggt gatgatttct ctgcggttat cacccaggcg
     2341 caacagatgg caggcttccc gtacagcgaa attccgcacc ttatcaccgt gggttttggt
     2401 cgccagacgc tgcttggcgc tgctgatacg ctgattgatc tggtgagccg tgaaaaactg
     2461 cgtcatatct tcctgcttgg tggctgtgac ggcgcacgcg gcgagcgcca ctacttcacc
     2521 gatttcgcca ccagcgtgcc ggatgactgc ctgatcctga ccctcgcctg tggtaaatat
     2581 cgctttaaca aacttgagtt tggcgatatc gaaggtctgc cgcgtctggt agatgcaggt
     2641 caatgtaacg atgcttactc agcgattatt ctggctgtca ctctggcaga gaaactgggc
     2701 tgcggtgtca acgatctgcc gctgtcgctg gtgctctcct ggtttgaaca gaaagcgatc
     2761 gtcattctgc tgacgctgct ttctctgggc gtgaaaaata tcgtcaccgg cccgactgca
     2821 cctggtttcc tgacaccaga cctgctggcg gtgctgaacg agaaattcgg cctgcgttct
     2881 atcaccactg ttgaagaaga catgaagcaa ctgttgagcg cgtaaggagt ttgtcgatga
     2941 cgatgccaac gaatcaatgc ccgtggcgga tgcaggttca tcacattacg caagaaacgc
     3001 cggatgtgtg gacgatttcc ctgatttgcc acgattacta cccatatcgc gccgggcaat
     3061 atgcactggt cagcgtgcga aactcagcgg aaacgctgcg tgcttacacc atttcctcca
     3121 cgccaggcgt gagtgaatat atcaccctga ccgtgcggcg gattgatgac ggtgtcggct
     3181 cccagtggct gacgcgcgat gtaaaacgcg gtgattatct ctggctttcg gacgcgatgg
     3241 gggaatttac ctgcgacgat aaagcagaag ataaattcct gttgctggcg gcaggctgcg
     3301 gcgtcacgcc gattatgtcg atgcgtcgct ggcttgcgaa gaaccgtcca caggccgatg
     3361 tgcgggtgat ctacaacgtg cgtacgccgc aggatgttat tttcgccgat gagtggcgta
     3421 actatccggt aacgctggtg gcagaaaata acgttaccga aggctttatc gctggtcgtc
     3481 tcactcgcga actgctggca ggtgtacctg acttagcttc acgtaccgtg atgacctgcg
     3541 gcccggctcc gtatatggat tgggtagagc aggaagtgaa agcgctcggc gtgacgcgtt
     3601 tctttaaaga gaaattcttc accccagtag cagaagcggc gaccagcggt ctgaaattca
     3661 ccaaactgca accggcacga gaattttacg ccccggttgg caccacgcta ctggaggcgc
     3721 tggaaagcaa taacgttccg gttgtcgctg cctgccgtgc gggtgtttgc ggctgctgta
     3781 agacaaaagt ggtttccggt gaatatacgg tgagcagcac aatgacgctg atcgacgccg
     3841 aaatcgctga aggttacgta ctggcctgct cctgccatcc gcagggggat ttggttctcg
     3901 cataatcgcc ttatgcccga tgatattcct ttcatcgggc tatttaaccg ttagtgcctc
     3961 ctttctctcc catcccttcc ccctccgtca gatgaactaa acttgttacc gttatcacat
     4021 tcaggagatg gagaaccatg aaacaaacgg ttgcagctta tatcgccaaa acactcgaat
     4081 cggcaggggt gaaacgcatc tggggagtca caggcgactc tctgaacggt cttagtgaca
     4141 gtcttaatcg catgggcacc atcgagtgga tgtccacccg ccacgaagaa gtggcggcct
     4201 ttgccgctgg cgctgaagca caacttagcg gagaactggc ggtctgcgcc ggatcgtgcg
     4261 gccccggcaa cctgcactta atcaacggcc tgttcgattg ccaccgcaat cacgttccgg
     4321 tactggcgat tgccgctcat attccctcca gcgaaattgg cagcggctat ttccaggaaa
     4381 cccacccaca agagctattc cgcgaatgta gtcactattg cgagctggtt tccagcccgg
     4441 agcagatccc acaagtactg gcgattgcca tgcgcaaagc ggtgcttaac cgtggcgttt
     4501 cggttgtcgt gttaccaggc gacgtggcgt taaaacctgc gccagaaggg gcaaccatgc
     4561 actggtatca tgcgccacaa ccagtcgtga cgccggaaga agaagagtta cgcaaactgg
     4621 cgcaactgct gcgttattcc agcaatatcg ccctgatgtg tggcagcggc tgcgcggggg
     4681 cgcataaaga gttagttgag tttgccggga aaattaaagc gcctattgtt catgccctgc
     4741 gcggtaaaga acatgtcgaa tacgataatc cgtatgatgt tggaatgacc gggttaatcg
     4801 gcttctcgtc aggtttccat accatgatga acgccgacac gttagtgcta ctcggcacgc
     4861 aatttcccta ccgcgccttc tacccgaccg atgccaaaat cattcagatt gatatcaacc
     4921 cagccagcat cggcgctcac agcaaggtgg atatggcact ggtcggcgat atcaagtcga
     4981 ctctgcgtgc attgcttcca ttggtggaag aaaaagccga tcgcaagttt ctggataaag
     5041 cgctggaaga ttaccgcgac gcccgcaaag ggctggacga tttagctaaa ccgagcgaga
     5101 aagccattca cccgcaatat ctggcgcagc aaattagtca ttttgccgcc gatgacgcta
     5161 ttttcacctg tgacgttggt acgccaacgg tgtgggcggc acgttatcta aaaatgaacg
     5221 gcaagcgtcg cctgttaggt tcgtttaacc acggttcgat ggctaacgcc atgccgcagg
     5281 cgctgggtgc gcaggcgaca gagccagaac gtcaggtggt cgccatgtgc ggcgatggcg
     5341 gttttagcat gttgatgggc gatttcctct cagtagtgca gatgaaactg ccagtgaaaa
     5401 ttgtcgtctt taacaacagc gtgctgggct ttgtggcgat ggagatgaaa gctggtggct
     5461 atttgactga cggcaccgaa ctacacgaca caaactttgc ccgcattgcc gaagcgtgcg
     5521 gcattacggg tatccgtgta gaaaaagcgt ctgaagttga tgaagccctg caacgcgcct
     5581 tctccatcga cggtccggtg ttggtggatg tggtggtcgc caaagaagag ttagccattc
     5641 caccgcagat caaactcgaa caggccaaag gtttcagcct gtatatgctg cgcgcaatca
     5701 tcagcggacg cggtgatgaa gtgatcgaac tggcgaaaac aaactggcta aggtaaaaag
     5761 ggtggcattt cccgtcataa taaggacatg ccatgattga tttacgcagt gataccgtta
     5821 cccgaccaag ccgcgccatg ctcgaagcga tgatggccgc cccggttggg gacgacgttt
     5881 acggagacga ccctaccgtt aatgctctgc aggactacgc agcagagctt tccggtaaag
     5941 aagccgccat ttttctgcct accggcactc aggccaacct ggtcgctctg ctcagtcact
     6001 gcgaacgcgg cgaagagtat attgtcggtc aggccgcgca taactatctg tttgaagccg
     6061 gtggcgcggc ggtgctgggc agtattcaac cgcaacccat agacgcggct gccgacggca
     6121 cgctaccgct ggataaagtg gcgatgaaaa tcaaacccga cgatatccat ttcgcccgca
     6181 ccaaattact cagtctggaa aacacccaca acggcaaagt gttgccgcgg gaatacctga
     6241 aagaagcatg ggaatttacc cgcgagcgca atctggcgct gcatgttgac ggtgcgcgca
     6301 tctttaatgc cgtggtggct tacggctgcg aactgaaaga gatcacgcaa tattgtgatt
     6361 cgttcaccat ttgcctgtcg aaaggtcttg ggacgccagt cggttcatta ctcgtcggta
     6421 atcgtgatta cattaaacgt gccattcgct ggcggaaaat gacaggtggc gggatgcgcc
     6481 agtccggcat tctggctgcc gccgggatat atgccctgaa aaataacgtt gcgcgcttgc
     6541 aggaagacca cgacaacgct gcctggatgg cggagcagct gcgtgaagca ggcgcggatg
     6601 tgatgcgtca ggacaccaat atgctgtttg ttcgcgtcgg ggaagaaaat gctgccgcgt
     6661 taggcgaata catgaaagcg agaaacgtgc tgattaacgc ctcgccgatt gtccgcctgg
     6721 tgacgcatct tgacgtctcg cgcgaacaac tggcggaagt cgccgcccac tggcgtgcat
     6781 tcctggcgcg ttaaggagag agacgtgccg caacgcattt tagttctcgg tgccagtggc
     6841 tacattggtc agcatctggt gcgcacactc agccagcaag ggcatcagat cctggcggcg
     6901 gcacgtcatg tcgacaggct tgcaaagctg caactggcaa acgtcagttg ccataaagtc
     6961 gatctcagct ggccggataa cctaccggcc ctgttgcagg atatcgatac ggtctatttt
     7021 ctggtgcaca gcatgggcga aggcggcgat tttatcgctc aggagcgcca ggtggctctc
     7081 aacgtccgcg atgcgctacg tgaagtacca gttaagcaat taatctttct tagttcgttg
     7141 caggccccgc cacatgagca gtcggatcat ctgcgtgctc gtcaggctac ggcggacatt
     7201 ctgcgtgaag cgaatgtacc cgtgaccgaa ctgcgggccg gaattatcgt tggcgcaggt
     7261 tccgcggcgt tcgaagtcat gcgcgatatg gtctacaacc tgccagtctt aacgcctccg
     7321 cgctgggttc gttcacgcac cacgcccatt gcgctggaaa acttgctgca ctatctggtt
     7381 gcgttgttag atcatccggc cagcgaacac cgcatcttcg aagccgccgg accagaggtg
     7441 ctcagttatc agcaacagtt tgaacatttt atggcggtga gcggtaagcg ccgctggttg
     7501 atccccatcc ccctccccac ccgctggatt tcggtgtggt ttctcaatgt gattacttcc
     7561 gtaccgccca ccaccgccag ggcgttgatt caggggctga aacacgatct gctggcggat
     7621 gataccgcgc tacgtgcact catcccacaa cggctgatcg ctttcgatga cgcggtacgt
     7681 agcacgttga aagaggagga aaaactggtc aactccagcg actggggcta cgacgctcag
     7741 gcctttgccc gctggcgacc ggagtacggt tattttgcca aacaggcggg gtttaccgtt
     7801 aaaacgtccg ccagccttgc tgctttatgg caggtagtga accaaatcgg cggtaaagag
     7861 cgttatttct ttggcaatat tttgtggcag acacgggcgt tgatggaccg cgcgatcggt
     7921 cataagctgg cgaaaggccg cccggagcgc gaatatttac agactggcga tgcggtggat
     7981 agctggaaag tgattgtcgt tgaaccggaa aaacaactta cgttgttatt tggcatgaaa
     8041 gcgccggggc tgggacgact gtgttttagc ctggaagata aaggcgacta tcgtactatc
     8101 gatgtccgcg ctttctggca tccgcacggt atgccggggc tgttttactg gttattgatg
     8161 atccccgcgc atctgtttat ttttcgcgga atggcaaaac aaatcgccag actggcagaa
     8221 caaagcacag attaatcgac aaaacctgcg ttattctttc atgtttccca ttgcatcatg
     8281 ggggaaatca cggaagaatg cgcacgttat tttctcaaca acagtggatt gatatgaagg
     8341 tactggttac cggcgccacc agcggcttag gtcgaaacgc ggtagagttt ttatgccaga
     8401 aaggcatcag cgtgcgagcg accggtcgca acgaggcaat gggcaaattg ctggaaaaaa
     8461 tgggcgcaga gtttgttccg gcggatctga ccgagctggt ttcatcacaa gctaaagtga
     8521 tgctcgcggg cattgatacg ctgtggcact gctccagctt tacctcaccc tgggggacac
     8581 aacaggcttt cgatctggct aacgttcgcg ccactcgccg cctgggtgaa tgggctgtcg
     8641 cctggggtgt gcgtaacttt attcatatct cttccccctc cctgtacttc gattatcacc
     8701 accatcgcga tattaaagaa gattttcgcc ctcaccgctt cgccaacgag tttgcccgca
     8761 gcaaagcagc cagcgaagaa gtgatcaata tgctttcgca ggcgaatcca caaacgcgct
     8821 ttactattct gcgcccacaa agtctgttcg gaccgcacga taaagtcttt attccccgtc
     8881 tggcgcatat gatgcaccac tacggcagta ttctgttacc gcatggcggc agtgcgctgg
     8941 tcgatatgac ctactatgaa aatgccgtgc acgcaatgtg gctggcaagc caggaagcct
     9001 gcgataagct accttccggg cgtgtgtaca acatcaccaa cggcgagcat cgcacactgc
     9061 gcagcatcgt gcagaagctg atcgacgagt tgaatattga ctgtcgtatt cgttccgtcc
     9121 cctacccgat gctggatatg atcgcccgca gcatggagcg tttaggccgc aagtcagcaa
     9181 aagagccgcc gctgacccac tacggcgtct ccaagttgaa ttttgacttt acgctggata
     9241 ttacgcgtgc gcaggaagag ttaggttatc agccggtcat caccctggat gaaggtatcg
     9301 agaaaactgc cgcctggcta cgcgaccacg gaaaactgcc gcgctaatcc tgcccgtatt
     9361 tctccagcaa tgcttcggca atcgcctgag tttctgcatc cgcttcgccg ttatataacg
     9421 tcgggcggaa atgcatctgg aatgccataa tcacgcgccg ctgctcgcgc ggtgtcatat
     9481 caggtttaac gtcataaccg tagcgcgcca aaagctccag caatgacgcg gtatctaccg
     9541 gtgtgtgcgg cgcgcgcccg gcaaggtaaa agttaacccg ctgcgcatcc ggccaggcac
     9601 caatcccctg ctgcgccagt tgctgccagg gaaataatgg ccccggatcg tctttgcgct
     9661 gcggtgcgat atccgcatgt gccactacgt tttccggctt gatgtgataa cgggcaataa
     9721 tatctttcgc cagtggaata agcgcctgaa tctgtgccgg ttcaaacggg gcaaaatatt
     9781 tcactccggc cgatttttgc cagccacggt tttccagctc aatgccaata gaggtgtcgt
     9841 taaggcgcgt tgccccgcgc caggcgctaa tccccgcatg ccaggccagt tcttgttccg
     9901 gcaccagttg ccagatgcgc ggtttaccgt tgtatcgcgg tggtaccgca gggaccagat
     9961 aatgcgagct gacctgctta tcggtcagtg tcgccagcga gctatcaaaa tcatctgcgg
    10021 tgtagtggat caccagcact ttaatgcgcg gatacgccgc ctgcgcctgg cgtcgggtat
    10081 caagctgata tccctctttc tcgacaatgc ctttttcgcc tgcacaccct gccaataaca
    10141 gagcggcagc gaccagccag aagaatcttc tcatcgacgc gttttcaccg ccgtaccgct
    10201 gacgctaacc atcagcatac tgccgttttg cccgaccgtt tcgtagtcga tatcaatacc
    10261 gacgacggca tcggccccca gcgcccgcgc ctgggagcct aattcctcaa aggcgatctc
    10321 ccgtgcttta cgcagttctt tttcatacgc accggaacgt ccgccaacga tatcgcggat
    10381 accggcaaag aaatcacgga aaatattggc acctaaaatc gcttcgccgg tcaccacacc
    10441 gcaatattca acgatggtct ggccttccag agttggggtt gtagaaaatt gcatgatcga
    10501 tctccttgtt tgctaagcct tcgatctcaa aagcattatc agactgatac gctattattg
    10561 aaaggatatc attattatcg tagaacgctt tcagagcgat cgcttataag gaaatcatta
    10621 tgcgctacag caaattgaca atgcttatcc cctgcgcact gctcctcagt gcctgcacca
    10681 cagtcactcc agcttataaa gataacggca cacgcagtgg tccttgcgtt gaaggaggcc
    10741 cggataacgt ggcccagcaa ttttatgact accgcatttt gcaccgcagc aacgacatca
    10801 ccgccttgcg cccttatctg agcgacaaac tggcgacact gcttagcgat gcctcccggg
    10861 ataataacca tcgggaacta ctgaccaacg atccattctc cagtcgaacc accttgccag
    10921 atagcgccca cgttgccagt gcatcgacta tccctaatcg tgatgcccgt aacattccat
    10981 tgcgcgtgga tctcaaacag ggtgaccagg gttggcagga tgaagtgtta atgattcagg
    11041 aaggccagtg ttgggtcatc gacgatgtgc gttacttagg cggtagcgtt catgccacgg
    11101 cgggtacgct ccgtcagtcc atcgagaatc gctaacgcct tgatcaacca ataaaccccg
    11161 taaattgtcc ggcatttcgt gaggaatgcc gacatttatg ctcgccgacc accgcccccg
    11221 ttattttgtg ctatgtttat tgaataatgc gctttgcttt taacttttaa agcagaaata
    11281 ttgcataatt attctgtcaa aggtactatc ttcgacctca atagctatca gactgccagt
    11341 atacgagtgt caatgagtat tcaattaaac ggcattaatt gcttctacgg cgcgcatcag
    11401 gcgctgttcg atatcacgct ggattgccca cagggcgaaa cgctggtgtt acttggcccc
    11461 agcggcgcgg gtaaaagctc gctgctgcgt gtactcaatc tgcttgagat gccgcgctcc
    11521 ggtacgctca acattgcagg caaccatttc gatttcacca aaacaccctc tgacaaagcg
    11581 attcgcgatt tgcgtcgtaa cgttggcatg gtgtttcagc aatacaacct gtggccgcat
    11641 ctgaccgtgc agcaaaacct gattgaagcg ccctgccgtg tactggggtt gagtaaagat
    11701 caggcgctgg cccgtgcaga aaaactgctg gaacgtctgc gtctcaaacc ttatagcgat
    11761 cgttacccgc tgcatctttc tggtggtcag cagcagcgtg ttgctattgc ccgtgcgttg
    11821 atgatggaac cgcaggtact gctgttcgat gaaccgaccg ccgcactgga cccggaaatt
    11881 acggcacaaa tcgtcagcat cattcgtgag ctggcagaaa cgaatattac ccaggtgatc
    11941 gtcacccacg aagttgaagt ggcgcgtaaa accgccagcc gagtggtgta tatggaaaat
    12001 ggtcatatcg tagaacaagg cgacgcgagc tgctttaccg agccgcaaac cgaagcattt
    12061 aaaaactatc tctctcacta agattcggga taacaacaat gaaaaaagtt ctgattgccg
    12121 cgttaattgc aggttttagt ctttccgcca cagctgccga aaccattcgt tttgctaccg
    12181 aagcctccta tcctccgttt gaatcgattg atgcaaacaa ccagatcgtt ggttttgacg
    12241 tcgacctggc acaagcgctg tgtaaagaga ttgatgcaac ctgcactttc tctaaccagg
    12301 cgtttgacag cctgatccca agcctgaaat tccgtcgcgt agaagccgtg atggcgggca
    12361 tggatatcac tccggagcgt gaaaagcagg tgctgtttac caccccgtac tatgacaact
    12421 ctgccctgtt tgtgggtcag caaggcaaat acaccagtgt tgatcagctg aaaggcaaaa
    12481 aagtcggcgt acagaacggg acgacacacc agaaattcat tatggataag cacccggaaa
    12541 tcactaccgt tccgtatgac agctaccaga acgcaaaact ggatctgcaa aacgggcgta
    12601 tcgacggcgt cttcggtgac accgcagtgg tcactgagtg gctgaaagat aacccgaaac
    12661 tggcggcggt gggcgacaaa gtgaccgata aagattactt cggcactggc ctcggcatcg
    12721 cggtacgtca gggcaacact gagctgcagc agaaactcaa cactgcgctg gaaaaagtga
    12781 agaaagatgg cacttacgaa accatctaca acaaatggtt ccagaagtaa ttcctgatga
    12841 atgaattttt tcctttagca agcgccgccg ggatgaccgt cggccttgcc gtttgtgcat
    12901 tgattgtcgg gctggcgctg gcgatgttct ttgcggtatg ggagtcggca aaatggcgtc
    12961 ctgtcgcgtg ggcaggttca gcgctggtaa ccattctgcg tggcctgcca gaaattctgg
    13021 tggtgctgtt tatctatttt ggctcctcgc agctgctgct gacgctttcg gatggcttca
    13081 ctatcaatct tgggttcgtg cagatcccag tgcagatgga cattgagaac ttcgacgtta
    13141 gcccgttcct ttgtggtgtc atcgctctgt cactgctgta tgccgcctat gcctcgcaaa
    13201 cgcttcgggg cgcgttgaaa gcggtgccgg tgggtcagtg ggagtctggt caggcgctgg
    13261 ggctgtcgaa atcggctatc tttttccgtc tggtgatgcc gcagatgtgg cgtcatgcgc
    13321 tgcctggcct cggtaaccag tggctggtgc tgctgaaaga taccgcgctg gtcagtttga
    13381 ttagtgtgaa tgatttaatg ctgcaaacaa aaagcatcgc tactcgtacc caggaaccat
    13441 ttacctggta cattgtggcg gcggcgattt acctggtgat caccctgctc agtcagtaca
    13501 ttctcaaacg cattgacctg cgcgcgacac gttttgagcg gaggcccagc taatgtttga
    13561 gtatttaccc gaactgatga aagggctaca caccagcctg acgctaaccg ttgcctcgct
    13621 gattgtggca ctgattctgg cattgatttt taccatcatc ctgacgctga aaacgccggt
    13681 gctggtgtgg ctggtgcggg gttatatcac gctgtttacc ggtacgccgc tgctggtgca
    13741 gatcttcctg atttattacg ggccgggcca gtttccgact ttgcaggagt atccggcact
    13801 gtggcatttg ttgtcagaac cgtggttatg tgcgctgatt gcgttgtcgc tgaatagtgc
    13861 ggcgtatacc acgcagctgt tttacggtgc aattcgtgcg atcccggaag gtcagtggca
    13921 gtcctgtagc gccctgggaa tgagcaaaaa agatacgctg gcgatcctgc tgccgtatgc
    13981 ctttaaacgc tcgctctctt cttattccaa cgaagtggtg ctggtattca aaagtacctc
    14041 tctggcatac accattacgc tgatggaagt gatgggatac agccagttgt tgtacggacg
    14101 cacctacgat gtaatggtgt tcggtgcggc agggattatt tacctggtcg ttaacggcct
    14161 gctgacgctg atgatgcgtc tgatcgagcg caaagcgctg gcattcgaac ggcgaaatta
    14221 atgtggctgc gtacattcgc cggggggttt tgtaggtctg ataagacgcg ccagcgtcgc
    14281 atcagacatc agcacggtgc ctgtgccgga tgcggcgggg acgccttatc cggcctacat
    14341 agtgcataaa ttcttataat gaagacggac aacccactaa gttgtccgtc ttttttattt
    14401 catttaaatt atttaatcat gtttattgca tataaattca cttgatggca ttgttatccc
    14461 atgccgcaga cacggccaaa aatcataaga ttgacagacg ggagttccat catgaaaaag
    14521 ttagttcttg ccgctttact tgcttccttt actttcggtg cttctgccgc agagaaaatc
    14581 aattttggca tttcagccac ctatccaccc tttgaatcta taggtgctaa taatgagatt
    14641 gtcggctttg atatcgatct ggcaaaagcc ttgtgcaaac aaatgcaggc agaatgtact
    14701 tttactaatc acgcgttcga cagcctgatc ccgtccctga aattcagaaa atatgacgcc
    14761 gtaatctccg gtatggatat caccccggag cgtagcaaac aggtatcgtt taccacgccc
    14821 tactatgaaa actcagccgt cgtgattgcc aaaaaagata cctacaaaac gtttgccgat
    14881 ctgaaaggca aacgtattgg gatggaaaac ggtactacgc accagaaata tattcaggat
    14941 cagcacccgg aagtgaaaac tgtctcttat gacagttatc agaatgcctt tatcgatctg
    15001 aaaaatggtc gtattgatgg ggtatttggt gacacagcgg tggtaaacga atggctgaaa
    15061 accaatccac aacttggtgt tgctactgag aaagtgaccg atccgcaata ttttggcacc
    15121 ggcctgggca tcgctgtacg tccggataac aaagccctgc tggaaaaact gaataacgcg
    15181 ctggcagcaa ttaaagctga cggtacttat caaaaaatca gtgaccagtg gttcccacag
    15241 taagattcag aaagccgcaa ccgcggcttg agactgatga caaaggtaaa attgcctgat
    15301 gcgctacgct tatcaggcct acatggccca tgcaatgtat tgaatttgca cgcttttgta
    15361 ggccggataa ggcgtttacg ccgcatccgg cataaacaac gcgcactttg tcagcaatct
    15421 gaagccgcac atgcggcttt tttattgctt caccagcagc gtcagcactt catagtgcgc
    15481 ggtatgcggg aacatatcga aaagctgcac ccgttcaata cgaaacccag gcagttcgcg
    15541 gatatctttc gccatagttt gggcgttaca gctggagtag atgataaaac gcggtgccat
    15601 cgttgagaga taatcacaca gcggtttacc aatgccgcgg cgcggcgggt taaccagcac
    15661 cagctccggc acatccccct gagcggtggc aaactgagtg gagtccagcg cctgaaattg
    15721 caaacgcgtt aagcccagtt cagcggctga ctgctttgca caggcaatgg cctctgatgc
    15781 aatttcgatc ccggttaact gcatgtcagg cgtcgcgcag tgtaaaccaa agccccccac
    15841 accgcagaac agatcccaca tatgtttaac cggcagctgt cgtacccagt cgcgcgcggt
    15901 ggcgtacaac tggctggcga ccgccggatt agtctggaag aaactttgcg gacggatcca
    15961 cagcggtacg tcattaaaac gctccgccag tgcctgttgt tcggtcaggt agatctccgt
    16021 ctccccttcc ataatcgcca tatgtaccgg ctgaatattg acggtaataa ctttcagctg
    16081 cggtagttgt tcgtgtaacc acggcagcgc cttacgcagt tgcgccagct tggtatcaga
    16141 acgcagtaca aagcgcagca tcatgcctcc atcactctgg ctttcagtca gcagaatgta
    16201 tttcagttcg ccacgcttac gcgccacgtt gtagggcgtt aaccccgctc gggcgataaa
    16261 cggttttagc gccgcaaaaa cgggcgcaaa tgaggcagga taaagcgggc agtcacaaag
    16321 gtcttctggt gtgccatcgc gatgcagcat accgagcagt ggtttttcaa cgctaccact
    16381 caccaccatt ttggctttat tacgaaaccc ttgttccggg cctgacaccg gcgcgcacca
    16441 ttcctcaacc ggaaagtcgg cgagcagatt tttaagatcg gcggttttag cggagagttg
    16501 ctctggaatc ggctgcatta tccactgaca ggaacgacag cgacccgcgt cgtaaagtgc
    16561 gcactgcata cattgacctt cacatcatca ggggcgacga ttatacacat tattgcaact
    16621 ggaagaaccg ccgactggtc gagggaacga acagcagcat caggatgagc atatccggca
    16681 gcttctgcag catcaggcta tggaagattt cacgttttga ttcaccggga atgctgaaca
    16741 gctccggata accgtacccc agcgaagccg cccacaagta acttgcggcg gtgatttgtg
    16801 tcagcagata tagccagcgc gcccagcgac gccctttcac cagtgaaaac gcacaccaga
    16861 tctcaatgaa aaccagcacc agactgctta aaaagaccag cgttaaactc caggtttgta
    16921 cgctgcgatg aatgaactcg ccaataccgc gcacgcccag cgtattgaaa atcatcagca
    16981 cgtcgaggcc acggatcata ataatggcga gcgccgccac ctgcaccagc gcaggcacat
    17041 tcaggcgagc atgagatgaa gatgttttct taaaaaatcc caacgtttcg tcttccatga
    17101 aaacaatgcc gcgacatgcg cggcattatg tagccaggtt ggcaaatttt agtgtcttca
    17161 gccacgtctt gcacgctgga tgtcgcgtat ccgctgtttt tctgcgcgag ccatcagata
    17221 ccaggcgata aatccgacaa ttccgaccgc gccgaggatc aatgttgcca gggcgttgat
    17281 ttccggattc acccccatcc gcacgctgga aaagaccagc atcggtaacg tggtggctcc
    17341 cggcccggaa acaaagctgg cgatcaccag atcatcaagc gacaaagtaa aagccagtaa
    17401 ccagccagaa atgatcgcgg gcatgatcat cggtagcgta atgacgaaaa acactttcag
    17461 cggcgtcgca ccgagatcca tcgctgcttc ttctatcgag cgatccagtt cccgcaatct
    17521 tgaagaaata acgaccgcca cataagccgt acaaaaagtg acatgcgcca gccagatggt
    17581 gagcataccg cggtccgcag gccagccaat ggcatgagca agcgcgacga ataataacaa
    17641 cagcgacaag cccgtgatga catctggcat taccagcggc gcggtgatca taaaggcaaa
    17701 gccatttgat ccgcgaaacc tgccaaagcg caccagcacc accgccgcaa tagttccgag
    17761 gatcgccgcc gccgtcgccg cacaggccgc aattgtcaga cttaaaccaa ccgcactcat
    17821 catcgcgtca tcgcgcaata actcaccata ccagcgcgtt gaccagccgg cccacaccgt
    17881 caccagcttc gagctgttaa acgaatagat aaccagcatc agcattggcg cgtagagaaa
    17941 ggtaaagccc agcagcaaaa tcacaatccg ccagggcgaa cgaactaccg gtaaattatt
    18001 catccgtgtt ctcccacgct tttttgctgg tgtttgtgga accacattat cggcacaatt
    18061 agcagcagca acatgatgat cgctaccgcc gaggccaccg gccagtcgcg gttattgaaa
    18121 aactcttgcc atagcacgcg cccgatcatg atgctgtccg ggccaccgag cagttccggg
    18181 atcacaaact cgcccacagc cgggataaac accagcatcg atccggcaat aatcccacct
    18241 ttagtcagcg gcacgatcac agtaaagaac gttttcagcg gtcgtgcacc gagatccagc
    18301 gctgcttcca ccagcgaata atcaatacga atcaacgcgg tataaatcgg cagtaccata
    18361 aacggcacgt aagcgtaaac aatgccgata taaacggcca gattggtatg cagaatggtc
    18421 agcggttgat cgataacccc cagccacagc agaaaattat tcagcacacc gttgtttttt
    18481 aatattccca tccaggcata aacgcggatc agaaacgagg tccacgacgg caggatcacc
    18541 agtagtaata aaatattacg ggtcgaaggc ttactgtgcg ccaccgccca cgccagcgga
    18601 tagccgatca gtaaacagca aaatgtcgaa atcgcagcca cctgtagcga ctggagataa
    18661 gcatcgaaat agagcggatc gtcggtcagt tgcagaaaat taccgagatt aagagtgatg
    18721 gacagttgcc cgtcagccca ctccatcagt tcggtataag gtggaatagc gcgcgccatc
    18781 tccgccaggc ttattttaaa gacaatcaga aatggcagca gaaacagcaa gatcaaccag
    18841 atatatggca acgcaatgac cagtttgcgc ccatgcttca tttgcagctg cgacaaccac
    18901 agcttaaatc cgcccggcgg tttcgactgg gcagcaggtt caagtgtact catctttgct
    18961 ccttaaaccg tcagcaccac acagctgtcc acttcccagc acaaacgcac ttcgtcgccc
    19021 caggtcggta accctttacg atgacgatgg gcgttttgta gctgggcgct aatcatctgc
    19081 ccacttttca gacgaacgtg atacaccgaa agatcgccga gataggcaat gtgtatcacc
    19141 tcccccaccg cgaagttaca accattggcg ggcggctctt cgcaaagcat gattttttcc
    19201 gggcgcagcg ccacatgtac cggcacgtta tcgaccaccg aggcatccgc gtcgactttc
    19261 agtggatgca ccagccccgg cgaatcaagc accaggccat cttcctgacg ctctttgagt
    19321 acgccttcaa agacgtttac cgagccaata aattcggcgc tatagcgggt agtcggatgc
    19381 tcgtagatct cttccggttc gccaatctgg acaaatttcc cacgattcat aatggcgatg
    19441 cgccccgcca tggtcatcgc ctcttcctga tcgtgggtga ccatcacaca agtcacaccg
    19501 acgcgctcca gaatatccac cacttcaagc tgcatccggt cacgcagctt tttatccagc
    19561 gcgcccatcg gctcatcgag cagtaatagt ttcgggcgct tcgcaaggct tcgggccagg
    19621 gccacacgtt gtcgctgacc accggaaagc tgatgcggtt tgcgtttggc gaactcctgc
    19681 atatgcacca ggccgagcat ctcattgacc cggctggcaa tttccgcttt cggtagtttg
    19741 tcctgtttca ggccaaaagc gatgttctgt tccacggtca tatgcggaaa cagcgcgtaa
    19801 gactgaaaca tcatattgat ggggcgcagg taaggcggaa cctgtgacaa atcgacgcca
    19861 tcaagcatta tctgtccggc agaaggttgt tcgaaacctg ccagcatacg cagcagcgtg
    19921 gacttgccac agccggatgc gcccagcagc gcgaagattt cacctttgta gatggtcagg
    19981 ctgacatcat ccaccgcatg ttgaccatcg taggatttgg tcaggttgcg gatttctaat
    20041 agcggcgtca gcgccttacg ggttttcgcc tgcgggcgag ggatagcgtc attcacggct
    20101 gctctccggc attgaatgtg tgcaagcgca ccataatggt gcgaattgcc ggcgggtgtg
    20161 gtgcgcccct ccggcatcta cgactgcgga ttattttccg ctcttcactt tggtccacgc
    20221 gcgggtgcgc acacggtcga ttttcggatc ctgcactttc agagtgaaca gcttcgcacg
    20281 aacatccgca ggcggataaa tacctgggtt ctcacggact tccgcactca ccagcggcgt
    20341 ggctgcttta ttggcgttgg catagaacac atggtcggaa atatgcgcta ctacatccgg
    20401 gcgcagcagg taattcagga actgataggc ttcgtctttg tttttggcat ccgcaggcat
    20461 ggcgaataca tcaaagaacg ccatcgcccc ttcttttgga atcgagaacg agacattcac
    20521 gccattcttc gcttccttcg cgcggtttga cgcctgccag acatcacctg cccagccgat
    20581 agcgacgcaa atatcgccgt ttgccaggtc gttaatgtat tgagatgaat ggaaataacg
    20641 aatgttcggg cgcagcttta acagcagatc tgttgccggt ccggtgtaat catccgcttt
    20701 agtgctgttg ggatctttgc cgagataatt caacacggta gcaaaaactt cttctggcgc
    20761 atccaggaaa gagacaccgc agcttttcag tttttccaga ttttcaggtt tgaggatcaa
    20821 gtcccagcta tcgacgggcg cgttttcgcc cagcaccgct ttaactttat caacgttata
    20881 gccaatcccg gtcgtcgccc acatataggg catagcaaat ttattgtcgg gatcgtgttt
    20941 ggcgaccagc ttcagcagtt ccgggtcgag attcttccac tccggcaatt tgcttttgtc
    21001 cagcggctgg aaaactcccg cagtcaactg gcgctccaga aagctggcag atggaaccac
    21061 cagatcaaag ccggtactcc cggccattaa tttgccttcc agtacttcgt tagagtcgaa
    21121 aacatcgtag acgactttaa taccggtttc tttttcaaaa ttggccaccg tgtccggggc
    21181 gatataatca gaccagttat aaatgtggag tgttttttgt tcagccgcga gcgtgccgac
    21241 agagacggcc atcagagcac ccgcaaccag acccgatagc cattttttat ttaaggcggt
    21301 catatctctt tccttctgaa agttcgttaa caaacgaaca aaagttgtca cactgaaaga
    21361 tatgcaataa acgtgcatat tttttatcgg cgcggtgtaa gaaaagagaa ctttctcccg
    21421 gccagcactg ctcgccatat aaaagcatcg caagaataac tttagccagg gtttgagact
    21481 atagctcgga ttaaaaaacg gtatttaaca aatttttatg catatttgct ctatgtgata
    21541 aagccaaatc gacacaagag aagtgaaata atctttaaga aaaggttaaa aacagcagat
    21601 aattttgcag cgcgcagcca ctgcaccagc gactgcgtgc tcgaaaggag ttatcagtgg
    21661 aggaaatagt tttcggtaac gttgttttgc ccttcatcat cagtcggtaa cagcagttga
    21721 tgggcattag cttcaagaat gaccatcgaa atctgctctt cgctctgacg cacgaaccat
    21781 gcaaactgct cataggttac gccctgcata acggataaag actggcaaac caccagcttt
    21841 ggcagattat catcctgcat atcaagaaat gctttcacgg tcagcgaact ggcattgatg
    21901 gcagataaat ccgccgccag cggcaatacg gctgaaggtc ggacttccgc catggcagaa
    21961 aacaggatcg tgttatcgat cagatcgatt ttggcatcaa agacaccgtc gaaattctgc
    22021 atatggggca gatgcagagc ctgacagtta tcacattcaa aaaaactcat ccccaggtca
    22081 tcgagccatt gacgcagcgt atccagacca ggaacgacca gcgatgtcat aattttgtac
    22141 aacctctttc gataaaaaga ccggcacagc ttacgcaaaa agcgcaggca aaaccatgat
    22201 cagtaatgtg attgcgacta accacccgtt ttcaggcaat attctgtcgt agcgtggcgt
    22261 tcgatccagc ggatcatttt acccgcgatg tcgataccgg tggttttttc tattccttcc
    22321 agccccggcg acgcattcac ctccatcacc aacggcccgc gattagcacg cagaatatcc
    22381 acaccagcaa cgtccagcgc catcgttcgc gcggctttta tcgcgatttc acgctcctgt
    22441 ggtgtgatac tggcgacgct tgccgcgccg ccacgatgca aattggaacg aaaatcgccc
    22501 tctttcgccc gccgttcaat cgcagcgacc acttcatcgc caacaaccag acagcggata
    22561 tcgcaccctt gcgcctcttt gatatattcc tgcaccagaa tatgcgcgtt cagaccgcgg
    22621 aaagcgtcaa tcacgctttc cgccgcctga cgcgtctccg ccagcacgac gccaattccc
    22681 tgcgtgcctt caaccaactt gaccaccagc ggcgcaccac cgaccatgtc gattaaatcg
    22741 ctggtatcat ccggcgaatg cgcaatgccc gtgacaggca ggtcgatgcc ctgacgcgcc
    22801 agcagttgca tggaacgcaa tttgtcacgc gcccgggcaa tggcgaccga ctcattgagc
    22861 ggatagctcc ccagcatctc gaactggcgc agtgccgccg tcccataaaa ggtaatggcg
    22921 gtgccaatac gcgggatcac tgcgtcaaaa tggggtaact tgcggccttt gtagtgaata
    22981 gaagacgccg caggatttat gttcatgtag caagaaagcg gatcaagaat ttcaaccagg
    23041 tgaccgcgct gtatagcggc ttcacgcagc cgcttacacg aatagagcgt tccatcccgg
    23101 gacaatatgg caattttcac cctgcacctc tctgtcagac ctggtcaaaa gcccgcgtat
    23161 catacatcga cgtggcggtt ttagcgcgtc gcccaaccct gtttgtgcaa ataatccaga
    23221 ataaatgggc ggctttcttt aatgattgtt cggcggatat gatcgctcca ggtatcccgg
    23281 cgattattgc tgccacgggt gaggtaatat tccgccagtt gctcgtcata ctgcgccagt
    23341 gcgcctttat ccagcggttg atagctgttt tcatgcacca aaatggaggc cggtaaacgc
    23401 ggcttaagat ccggattatc cgcaggccag ccaaggtaca gcccaaacag cggcagaaca
    23461 tgctgcggta atttaagcag tttcgtcacc gcttcaatat tattgcgcag gccgccgata
    23521 tataccccgc ccaatcccag cgattccgct gcgattaatg cattctgcgc catcattgcc
    23581 gtatcaacga caccgagcaa cagttgttcc gccaggccga gctgagcatc cggacagatc
    23641 tgtaaatggc ggttaaagtc ggcacagaac acccagaact ccgccgcttg cgctacgtgt
    23701 ttttgcccgc cggtcagcgt caccagttct tcacgtaacg ctttgtcggt aatgcgaata
    23761 atgctactgc actgcaaaaa actggaactg gacgtcgcac gggcgctgtt aataatcgcc
    23821 tcacgctgcg cttcggaaat gggttcatca gtgaaatggc gaatggagcg atggccacaa
    23881 ataagttcaa tggttggcgt cattatcttt ttctctttct gaacgtgaat attgcggtgg
    23941 acggttcatc agctgtgggg caagacgttt tgccacctga agaataacca ccaccgcagc
    24001 gggaagcatg agcaaaacac cgagaaaaat catcagaatc tgcacttctg gccgagaaaa
    24061 tggctcaggc agcgacaggg agtcgcttac cgacagcagc gccaccgcca gtagcatcat
    24121 tccgataaat tccagtatca acacgccttt aggcaattta ccgatcgcgc gcatacgctt
    24181 ccctctgcaa agtgagcctt cagtctaaaa cttttcactg tattgtgttt aacagttata
    24241 gcttttagca attaatgcaa caggttaaac ctactttcag cgaatacatt ttagcgtgat
    24301 cattacaggc ataaatctat gaggagagaa ataatgcaaa ccgttatttt tggtcgttcg
    24361 ggttgccctt actgtgtgcg tgcaaaagat ctggctgaga aattgagcaa tgaacgcgat
    24421 gattttcagt atcagtatgt agatattcgt gcggaaggga tcactaaaga agatctacaa
    24481 caaaaggcag gtaaacccgt agaaaccgtg ccgcagattt ttgtcgatca gcaacatatc
    24541 ggcggctata ccgattttgc tgcatgggtg aaagaaaatc tggacgcctg atcgtctgac
    24601 aagccctcgc gttgagggct ttactgattt tttctgtgct gtggtttaaa caaactactg
    24661 ataaataaga aacacagtgc ccccagcgca caccagaaca ccgcgcttag taaccatgcc
    24721 agctcttgcc agaatgagcg cgtcggtgaa aaaaacagcc gcataatgag catcgaacag
    24781 ggtgccgcca gcattgcgcc aaacagaggt ttcaggactt ctctacgctg tgaaaagaag
    24841 ctggcgactg ctccaggaag aatgaaaaat agcaagccga tttcaggatg cccggcagcc
    24901 cgaaaagcgc ctttcatgtg cgtcgccaga aaaaggcaca ccacaatgaa gaggacaaaa
    24961 cagcagattg cccccgccca acgttgttta tgtttcactc gttcctcctg acactgcgtc
    25021 tatcgaacac atttttcgcc agtgtggcgt tcagtaagat aaagccgctt cgcattccat
    25081 gctaatatag gccaacgcaa ttcatatagc cgttgatacc taatgtgatt acactagtaa
    25141 aatatattgt tactttacta tcgtttaggt gcgctgaatg aatctgcgcc ctgaattctg
    25201 gtaaaaaaca ttatcgtaaa ttaccatttc tttcaacagc ttactagtaa acaagaagtt
    25261 agcctccgtg aatataaacg tcgccgaatt gttaaatggg aattacattc tgttattatt
    25321 tgtggtcctc gcgcttgggc tatgtctcgg aaagttacga cttggttcga tccaactggg
    25381 taattccatt ggcgttttag tcgtatcgct gttattaggc caacaacatt tcagcattaa
    25441 caccgatgcg cttaatcttg gctttatgct gtttattttc tgcgtcgggg tcgaagccgg
    25501 accgaacttt ttttccattt tttttcgcga tgggaaaaat tacctaatgt tagcactggt
    25561 gatggttggc agtgcgctgg tgatcgcctt agggttaggt aagctgtttg gctgggatat
    25621 tggcctgacg gccggtatgt tagcaggctc tatgacgtcg acaccggttc tggtcggtgc
    25681 tggcgataca ctgcgtcatt ccggcatgga aagcaggcag ctctcactgg cactggataa
    25741 tctgagcctc gggtatgcct taacctattt aatcggtctg gtgagtttga ttgttggtgc
    25801 gcgttacttg ccgaaattgc agcatcagga cttacagacc agcgcccagc aaatcgcccg
    25861 cgaacgtggc ctggacactg atgccaaccg taaggtttat ttaccggtga tccgcgccta
    25921 tcgcgtcggc ccggaactgg tggcctggac cgacggcaaa aatctgcgtg aactgggtat
    25981 ttatcgacaa accggctgct acattgaacg tattcgacgt aacgggattc tggcaaatcc
    26041 agacggtgat gccgtgctac aaatgggcga tgaaatagcg ttggtaggct atcccgacgc
    26101 ccatgcccga ctcgatccca gcttccgtaa cggtaaagaa gttttcgatc gtgaccttct
    26161 cgacatgcgt atcgtcactg aagaagtggt cgttaaaaac cataacgctg taggtaaacg
    26221 tctcgcacaa ctgaagttga ccgatcacgg ttgcttcctt aaccgcgtca ttcgtagcca
    26281 gattgagatg ccgatagatg acaacgtcgt gcttaacaaa ggtgacgttt tacaagtcag
    26341 cggcgatgcc cgccgcgtaa aaaccatcgc cgatcgcatc ggctttatct cgattcacag
    26401 ccaggtcact gacctgctgg cattctgcgc cttctttgtt attgggctga tgatcgggat
    26461 gatcaccttc cagttcagca cattcagttt cggcatgggg aacgctgccg ggttgttatt
    26521 cgccggaatt atgctgggct ttatgcgtgc taaccacccg accttcggtt acattccgca
    26581 gggtgcatta agcatggtga aagagttcgg cttgatggtg tttatggcag gcgttggtct
    26641 gagcgccggt agcggtatta ataacggcct gggcgcgatt ggcggtcaga tgttgattgc
    26701 cggattgatt gtcagtctgg tgcccgtggt tatctgtttc ttgttcggtg cttatgtatt
    26761 gcgaatgaac cgcgcgctgt tgttcggcgc aatgatgggc gcacgtacct gcgcgccggc
    26821 aatggagatc atcagtgata cagctcgcag taacatcccg gcgctgggct atgcgggcac
    26881 ctatgcaatc gccaacgtcc tgctgacgct ggcagggaca atcatcgtca tggtatggcc
    26941 aggattagga taaaactgaa gttgccctga aaatgaaatt tttttgcaca accgcagaac
    27001 ttttccgcag ggcatcagtc ttaattagtg ccactgcttt tctttgatgt ccccattttg
    27061 tggagcccat caaccccgcc atttcggttc aaggttgatg ggttttttgt tatctaaaac
    27121 ttatctacta ccctgcaacc ctctcaacca tcctcaaaat ctcctcgcgc gatagcggct
    27181 tacggtcggt gacaaaatgc agcgtcatcc cctcaataaa cgcatcaagc gcgcgggcgg
    27241 ttccgggttc aaaccattgt tcgagcgttt gctgactgcg ctgcatccag ttttgcatta
    27301 ccgtttttaa tagcggtttt cggctagcca gcgcgtagag ctggtacatc agctccatgt
    27361 tatccggcgt tgcaacctgt gagctgtaga tcatatcggt gatagcctgg catgcgcccg
    27421 gagcatcact aacatcgcta aaaaatgcct gatattgccg ggacatgatc tcagtaaaac
    27481 tgctgaacgc ctccagtaac aactcatcaa ttcctgaaaa atagtaggtc atcgatccca
    27541 acggtacccc ggcaagggta gcaattttgc ggtgcgtaac agcatgtatt ccgtaaagtt
    27601 tcaccgcctc cagcgtggcc tggataattt tttctcgccg ttgcggatcg ttagcgcgac
    27661 gcatgtcatt tcctctctct gcaattgtgt acaaatgtac acaaccttgc taatgttgtc
    27721 ttccctcttc ttattttgac gtgatctatg accgtaaatt cttcacgtaa tgcattgaaa
    27781 cgccgaacct gggcgctgtt tatgttcttc tttttgccag gcctgttaat ggcgtcctgg
    27841 gcaacccgta cgcctgctat ccgcgatatt ctctctgtct cgatcgctga aatgggcggt
    27901 gttctctttg gtctgtcgat cggttcgatg agcggtattc tctgctcggc gtggttagtg
    27961 aaacgctttg ggacacgtaa tgtcatcctg gtcacgatgt cctgcgcatt gatcgggatg
    28021 atgatattaa gtctggcact ctggctgaca tcgcccctgc tctttgccgt tggtctcggc
    28081 gtctttgggg caagttttgg ttctgcggaa gtggcgataa acgttgaagg tgctgccgtt
    28141 gagcgagaaa tgaataagac ggttttgccg atgatgcacg gtttttatag cctgggcacg
    28201 ctggcaggcg caggtgtcgg gatggcactg acggcctttg gcgttccggc aacggtgcac
    28261 attttattgg cggcgctggt aggtatcgca cctatttata tcgccattca ggcaatccct
    28321 gacggtacgg gcaaaaatgc tgccgatggc acccagcatg gcgaaaaagg cgtacctttt
    28381 tatcgcgata tccagttgct gctgataggt gttgtggtgc tggcgatggc ctttgccgaa
    28441 ggttctgcca acgactggtt acccttatta atggttgacg gtcacggttt tagccctact
    28501 tccggctcgc tgatttatgc cggttttacc ctggggatga ccgttggacg cttcaccggc
    28561 ggttggttca tcgaccgtta cagtcgcgtt gccgtggttc gggccagtgc actaatgggg
    28621 gcgttgggta ttgggctgat tatttttgtc gatagcgcct gggtcgctgg ggtgtctgtt
    28681 gtactctggg gactgggtgc ctcgctgggc ttcccgctga ccatttctgc cgccagcgat
    28741 accggccccg atgcaccaac ccgcgtcagt gtggtagcaa cgaccggtta tctggctttc
    28801 ctcgtcgggc cgccgctgct gggctatctc ggcgaacatt atggattacg tagtgcaatg
    28861 ctggttgtac tggcgctggt tattctcgcg gctattgtcg cgaaagccgt cgccaaaccc
    28921 gataccaaaa cgcagacggc gatggagaat agttgatgag cattaaatta attgcggtag
    28981 acatggatgg tactttctta agcgatcaaa aaacctataa ccgtgagcgg tttatggctc
    29041 agtatcagca aatgaaagca caaggaattc gctttgtagt cgccagcggg aatcaatatt
    29101 atcagttgat ctctttcttc cctgaaattg ctaatgaaat tgcctttgtg gctgaaaacg
    29161 gcggctgggt agtgagcgaa ggcaaagatg tttttaatgg cgagctatcg aaggatgcgt
    29221 ttgctactgt cgtggaacat ttgctgacgc gcccggaagt ggaaattatt gcctgcggaa
    29281 aaaatagtgc ctatacactc aaaaaatatg acgatgccat gaaaacggtg gcggaaatgt
    29341 attatcaccg tctggaatac gtcgataact ttgacaactt agaggatatc ttctttaagt
    29401 ttggcctgaa tctttccgat gaactgattc cacaagtaca aaaagcatta catgaggcca
    29461 tcggcgatat tatggtgtcg gtccacaccg gcaacggcag catcgatctg attatccccg
    29521 gcgtacataa agccaatggc cttcgccaac tgcagaaatt atggggaata gacgacagcg
    29581 aagtggtggt ctttggcgat ggcggtaacg atattgagat gctgcgtcag gcaggcttta
    29641 gttttgcaat ggaaaatgcc ggtagcgcgg tcgtcgcagc ggcaaaatac cgcgcaggct
    29701 ccaataaccg tgaaggcgta ctggatgtga tcgataaagt tcttaaacac gaagcgccat
    29761 ttgaccaata aaaccggcag cacgcccggc aacacaatgc ctgaatgaag gctgcataat
    29821 tcgcggaaat taacccgctg cattatttca ggcgaaatga ttatgaaaaa ttgtctactg
    29881 ttgggcgcgc ttttaatggg ctttactggt gtggcgatgg cgcaaagtgt caccgtcgat
    29941 gtgccgagtg gatacaaagt ggttgtggtt cctgattcag tcagcgttcc acaagcggtc
    30001 agcgtcgcga ctgtgccgca aaccgtctat gtggctcctg cgccagctcc ggcttaccgc
    30061 ccgcatcctt atgttcgcca tcttgccagc gtaggtgaag ggatggttat cgaacaccag
    30121 attgacgacc atcaccatta attcgagaat gcctgatcgc acaaagcagt caggcatttt
    30181 tttacccttc gtgagaattt cccatctgtt tatcttttaa aaagataacc atcagcgaca
    30241 gccacaaaat tccgttgaca aggttgaaga gattaaacag tccgttgccc ccgttcagcc
    30301 aggcatgttt gctgatttca ataccaacgg taaagatcag catttgcagc attcccatcg
    30361 cggcagaaac cgtaccttta ctcatatcgc tggcaaacag ggttaatcgc accagtcccg
    30421 cattcgccag accaataccg aaagcataaa tacttaaccc ggcagtcatc cataaatacg
    30481 cgtgcgatga gataaccgtt gccgcagcag cgaccaatag accaatcata atcggccagc
    30541 cgcccataat aatcagcgaa cgtacggtgc ggcgcgaggt cagacgcgct aacagcaagt
    30601 tacccgcaat taacgccccg aaaataggca cttgcagcaa gccatattca tagctgctca
    30661 actgctcgcc ggtaatgatg ataatcggcg actgggcgat ccacgccagc aacggcagac
    30721 taacgaatcc cagcgccagc gcccccgcca caaagcggcc gttcttcagc accagcttat
    30781 agtcacgacc gagttctttc agtgacagtt tctcgcctat acgcgtggcg gtttcaggca
    30841 tggctcgttg cagaccgaaa aaggagatcg ctgccaatgc ggcaaacaaa acaaacatcc
    30901 cctcccaggg cagcacatgg atccacgccg cgcccaccag cggaccaagt agcggagcaa
    30961 tcagcgccac gttcgccatc agcgcggtga tcttgataca aaccgcctct tcgaaggatt
    31021 cctgaattgc ggcgtatccc acagcgccaa tgaaacagag gcttatgccc tgcaagaagc
    31081 gcaacagggt gaattgttca atgttttgcg ccagcaatat tgccagacag gtgacgataa
    31141 accacaccac tcccgccagc atcaccggac ggcgaccaat acgatccgac agcggcccca
    31201 gcagccattg taaaaacatc ccgcccgcca gatacgcggt catcgaagta ggaacccaat
    31261 caatgcccgc ctgatattgt tccaccacgg ccaacatacc gggttgaatc atatcgttgc
    31321 cgatataggt tgaaaattcg taaagcacca gacagagagg gaaaagtaac gcctgacgtc
    31381 caagcctggc accggaagct aatttatttt gcatgcaatt tcttcgccaa taataatcgc
    31441 gcagagttta ataaaagcgc agctaacgag aaagcgaatt ttgtagctga aaccacggtt
    31501 aagcacattc ttacattatt acgagtatag ctacgctttc tttaagtttt atttaaccta
    31561 tgcccgttac aatcacccac cgtaaacagg ccgcttgagg gaaataagac gatgccgctt
    31621 tacccagttt aacctgcact ttattctcaa cgacttgcct gtattggctc ccttttaatc
    31681 actttgcgtc gggaagttat gctggaaaat ttgaatctct ctctattctc tcttattaac
    31741 gcgacgccag actcggctcc gtggatgatc tcgttggcga tttttattgc taaagatttg
    31801 attaccgtgg tgccgttgct ggccgtggta ctttggttgt gggggcttac agcacaacgg
    31861 caactggtga taaaaatcgc tatcgcgctg gcggtcagcc tgtttgtgtc ctggacgatg
    31921 ggacatcttt ttccgcacga ccgacccttt gtcgaaaata tcggctataa cttcctgcat
    31981 catgcggcgg atgactcatt cccaagcgat cacggtacgg tgattttcac ctttgcactg
    32041 gcatttttat gctggcatcg cctgtggtcc ggctcacttt taatggtgct ggccgtcgtc
    32101 attgcctggt cgcgcgttta tcttggcgtc cactggccgc tggatatgct cggtggattg
    32161 ctggcaggta tgattggctg ccttagtgcc cagattatct ggcaagcgat ggggcataaa
    32221 ctctatcaac gtctgcaatc gtggtatcgc gtctgttttg cattaccgat ccgcaaaggc
    32281 tgggtgcgtg actgatctct gctaaaaagt gtagtattga gcggctcgct tcaataacta
    32341 ttcagaggga ttatggaaac acgtcgcgaa gagcgtatcg ggcagctgct gcaagaatta
    32401 aaacgcagcg ataagttaca tcttaaagac gccgccgccc tgcttggggt ttcggagatg
    32461 acgattcgtc gcgatctgaa caaccacagt gcgcccgtcg ttttgctcgg cggctatatt
    32521 gttctggaac cgcgcagtgc cagccattac ctgttaagcg atcaaaaatc ccgcctggtg
    32581 gaagaaaaac gccgggcggc aaaactggct gcgacgctgg tagaacccga tcagaccctc
    32641 ttttttgact gtggcaccac cacgccgtgg attattgaag cgattgataa tgaaatccct
    32701 tttaccgccg tttgttattc gctaaatacc tttctggcgc tgaaagagaa accccattgc
    32761 cgcgcgtttc tttgcggtgg tgaatttcac gccagcaacg ccattttcaa acccatcgat
    32821 tttcagcaaa cgctgaataa tttttgcccg gatatcgctt tttattctgc ggcgggcgtg
    32881 catgtcagta aaggcgctac ctgttttaat cttgaagagt tgccggtaaa acactgggcc
    32941 atgtcgatgg cgcaaaagca tgtgctggtt gtcgaccaca gtaaatttgg caaggtgcgt
    33001 ccggcgcgca tgggtgacct gaaacgcttt gatattgtgg tgagcgattg ttgcccggaa
    33061 gatgagtatg tgaagtacgc gcagacgcag cgcattaagt tgatgtatta atgacgtata
    33121 accggatgac gtttcgcgcc atccggttat cagaagatta agagaaccag ctgccgaacc
    33181 actgatggaa tttcatcatc acgaaatccc acacccgacc aaagaatccg ccctcttcca
    33241 cattttccat cacgatcagc ggacgctgct caatggattt accgttaagc tggaaatcaa
    33301 tggtcccgac aacctgacct tttttcagcg gtgcggtaag ctgcggttcc gttaacgtat
    33361 aactcgcttt caggtttttc agctgcccac gcggtatggt cactgagccc gcttcacctg
    33421 ccccgagatt cacttcgctc ttatcaccaa accagacgcg ctgagtcaca aaggtggcat
    33481 caggtttaat tggcgtcacg gtttcaaaga agcggaaacc ccaggtcaat aatttctcag
    33541 actcattaaa acggatacgg tcggttttcg cccccaacac tacggagatt aaacgcatat
    33601 cgccctgggt agccgaagca accagattat atcccgcgcc tgccgtggtt cctgtcttca
    33661 tgccatcaac attcagattg ctgctccaca gcagacggtt acggttaggc tgacgaattt
    33721 tgttgaaggt gaactctttc tctttatgaa tggcgtactc ttccggcaca tcgtggatca
    33781 atgctttacc cagcaatgcc atatcgcgcg cggtgctgaa ctgccccggc gcatccaggc
    33841 cgtgcaccgt ctggaaggta gtgttggtca gacccagttt tttggcataa ccattcatca
    33901 gaccaataaa tgactcctgg ctcccggcaa cgtaatcagc cagcgcaata caggcgtcat
    33961 taccggactg gataatcaca cctttgttca agtctgccac cgaaacctga tcgcccggtt
    34021 tgaggaacat taccgatgaa ccacgcagtg ccggatttcc cgtcgcccag gcatctttac
    34081 cgaccgtcac catatcggtg agtttaatct tatcggcctt aagcgcctgc ccaaccacat
    34141 agctggtcat gattttagtc aggctcgcgg gatccagttt ctcatccgca ttgccttctg
    34201 ccagcacttt accgctggcg taatccatta aaatccatgc acgcgcatcc acgctcggcg
    34261 cttcaacggt ttgttccgcc gcgaatgccg ttggggcaaa aaggaataaa aatgcagaac
    34321 ccgctgcaag accacgaagg agagaggagt attgcgtcat aaatgccacc cgagtatcca
    34381 ttcaaaaaaa atacgttata tcgccgtatg ataagtttgg tgattaataa cgcacacaca
    34441 aacttaaaga aaccgtaagt tggtaaagtt tttaaagttt atgcaatatc ctgccgcttc
    34501 gctgcttctg gtgtcatttt tttgccagct gttgcttaaa agttaacttt acttcaccat
    34561 cggagtcctg ttcagcctgt ggctgcctgt cggaaaaggg gtgagtatga ttacgctgtg
    34621 gggtcggaat aattcaacta acgtaaaaaa agtattgctg acgctcgaag aactggaact
    34681 accttatgag caaattctcg cgggccgtga gtttgggata aatcacgatg ctgattttct
    34741 ggcgatgaac cctaacgggc tggtgccgtt gttgcgtgac gacgaaagtg atctcattct
    34801 ttgggaatca aacgccattg tccgctatct ggcggcacag tacgggcaaa aacgcctgtg
    34861 gatcgactca ccggcacgtc gtgcggaagc ggaaaaatgg atggactggg caaaccagac
    34921 gctcagtaat gctcatcgcg ggatcctgat gggattagtc agaacaccac cggaagagcg
    34981 cgatcaggcc gccattgatg ccagttgcaa agagtgcgac gccctgtttg ccctgctcga
    35041 tgcggaactg gcaaaagtaa aatggttctc tggcgacgag tttggtgtgg gcgatatcgc
    35101 tatcgcaccg ttcatctaca atttgtttaa cgttggcctg acctggacac cgcgtccaaa
    35161 tctgcaacgc tggtatcagc aactcactga acgccccgca gtgcgcaaag tggtgatgat
    35221 tcccgttagc taattgcgtg ggctaacttt aagtaattcc ccactggact cgtcggtgag
    35281 aacgtataaa taaccgtcgg gtccagtgcg aacatcacga attcgctgcc ctctgtccgt
    35341 taaaatacgg ccatcttctg tcactttgtc gccgttgacg ctcatcacaa tgacatcttt
    35401 atctttcagc gcgccaataa ataatttttg ctgccactgg gggaatttat cgctgttata
    35461 gaaggccatg ccgctcacag cgggcgaatc tttccagtaa aaaacaggtt gctcggtccc
    35521 ggcgacgatc tcccctttcg cttccggtat cttaaagcct gaatagttga ttccccaggt
    35581 tgccagcggc cagccgtagt ttttgccttt ttgcgggata ttaatttcat caccaccgcg
    35641 cgggccatgt tcattcagcc acagtgcatt actccacgga ttcatcgcca ttccttgcgg
    35701 attacgaatg ccataagacc agatctcggc gcgcgcaccg gattccttta taaaaggatt
    35761 atcatccggg atttcgccct ggtcggtcag acgcaccagt ttgccctgta atttatccag
    35821 atcctgcgcc gtcgggcgct gattgttttc gcccagagca ataaaaagat aacctttacc
    35881 gtcgaatacc agccgcccgc caaaatggtt gccggtagac agttttggca tctggcgaaa
    35941 gacggtgcgg aagtcggtca cttttgagag atcatcactt aagcggccat aacccacagc
    36001 agttccggct ttgccatcat cgccaacttc ggaataactt aaccagatgc ggcgagactg
    36061 agcaaaatca ggcgctaaaa ccacgtccag caggccgccc tgcccgtgcg cccaaacgtc
    36121 cggaactccg gaaagcggcg cagataatcc ttttcctgct tgccagtgac gcaactcgcc
    36181 gccgcgcaga gtgattaaca taccgtgatt atcgggtaaa aaggccagtg cccagggatg
    36241 gtcgagtttg tcttgcagta cttcgacatt taccgttgca ggagccgccc agagagcgga
    36301 agaaagacaa ataaggggca caaggaaaaa ggattgtcga tgcataacgc ctccggattg
    36361 actctggctt aaagcgtagt cagtggagga gataacaaat tcatttttac aaaaacttaa
    36421 acatgaaggg ggagacgctt tctccccctt agttttcagg ccttctcaag catggcgtgc
    36481 ttctgcaggc tctggatact cagcgttaag ctcatcagac aattttcaag cttatcggcg
    36541 ttgacggtaa taacagtcgg gcaatcatgg tgcccactca tcaaacatac tgcggctgtc
    36601 gctaatgctt cttcagcatg atgaagagca ctccactctt cctgatccag atgaagattc
    36661 aaccgcagcg atttatcgtg cagttcgcga ttcagtttaa aaaagttatc tcgtagatga
    36721 ttgctttcgc tgacggacat gtatcctttt gccttcctca gttgcacgta tgcggcgagg
    36781 tcaacgcgtg cgtcgatcaa ccggttcagc agatcgattc gctgtctgtc aacgaacata
    36841 cttcgatcct cctcttccca gccttgttgc aattaaatag tatggctatt ttttgagcaa
    36901 aatgctgtcc aggatcaatt cttcacgccg aattaacaaa atttacattt ccttcgcctc
    36961 cgccagcgaa tgagattgcg atacaaattt tatccagaac tctgtagaat ccctgccctg
    37021 acctttcctg taactgaata ttttttaagc tatgagcaaa gtaactcccc agccgaaaat
    37081 cggctttgtt tcccttggct gtccgaaaaa ccttgttgat tcagagcgta ttctcaccga
    37141 actccgcact gaaggttatg acgtggtacc gagctatgac gatgcggaca tggtgatcgt
    37201 caacacctgc ggctttattg acagcgcggt acaagaatca ctggaagcca ttggtgaagc
    37261 gttgaatgaa aacggcaagg ttattgtgac cggttgtctg ggggcaaaag aagatcagat
    37321 ccgcgaagtc cacccgaaag tgctggaaat caccgggcct catagctatg agcaggttct
    37381 ggagcacgtt catcactacg tgccaaaacc gaaacacaac ccattcctga gcctggtgcc
    37441 agaacaaggt gtgaaactga cgccgcgtca ttatgcctat ctgaaaattt ctgaaggctg
    37501 taatcaccgc tgcaccttct gcattattcc gtctatgcgc ggcgacctgg tgagccgtcc
    37561 gattggcgaa gtgttaagtg aagcgaaacg tctggtagat gcgggcgtta aagagattct
    37621 ggtgatctcg caggatactt ccgcctatgg cgttgatgtt aaacatcgta ctggcttcca
    37681 caacggcgag ccggtaaaaa ccagcatggt cagcctgtgc gaacagttat cgaaactggg
    37741 gatctggaca cgtctgcact acgtttaccc ttatccgcat gtggacgacg tcatcccact
    37801 gatggcagaa ggcaaaatcc tgccgtatct ggacattccg ttgcagcacg ccagcccgcg
    37861 cattctcaaa ctgatgaagc gtccgggttc tgtagatcgc caactggcgc gcatcaaaca
    37921 gtggcgcgaa atctgcccgg aactgaccct acgctcaacc tttattgtcg gcttccctgg
    37981 cgagacagaa gaagatttcc agatgctact cgacttcctg aaagaagcgc gtctggatcg
    38041 cgttggctgc tttaaataca gcccggttga aggtgcagac gccaatgccc tgcctgacca
    38101 ggttccggaa gaagttaaag aagaacgctg gaaccgtttc atgcagctgc agcagcagat
    38161 ttccgccgag cgcctgcaag agaaagtggg ccgtgaaatt ctggtgatta tcgacgaagt
    38221 ggacgaagaa ggcgcgattg gtcgcagcat ggcagatgca ccggaaatcg acggcgcggt
    38281 ttatctcaat ggtgaaacca acgttaagcc gggtgatatc ctgcgtgtga aagtcgagca
    38341 cgccgatgag tacgatttgt ggggtagccg ggtttaatta attcaggccg ggcaaaatca
    38401 tttgtccggc ctgcgaataa tgattactgc cagctaatct gtgccctgcc gtttttctta
    38461 ctcttataca gccgctcatc cgccagcatt ttcaagcgtt cgacggtagg acattcattt
    38521 gaatgtgcta caccgatact ggtacttaaa ttaatgcttc ccacctggaa atgaacgatt
    38581 tcttttagaa tcgatagcaa ctcttccagc gttccacccg tataaatcac cgcaaattcg
    38641 tcaccgccga agcggtagac tttaccttta tctaccggga tctgtgattt aaggattttc
    38701 accactttca tcaacacttc atcgcccagc aaatgaccga aggtgtcgtt aatgtttttg
    38761 aatttatcga cgtcaaacag gcacaaataa ccgccttttt ccggcagcgc ttttaaatct
    38821 tcgtcaaagg attttctgcc cattgctttg gtcaggtcgt ccaggaacgc cgagttatac
    38881 atactgtaga gttttttgac atcggcagcc gaaaagaaaa gcccgccatc cagtacgcgt
    38941 tcaaaatggt tattaatgat ggcttctttc tccacaatac cacgattaat cactctgcgt
    39001 accagataga ggcaactggc acccgatatc actgccacca atgcggcaaa gaaaataatc
    39061 aatgtacaaa cccgcaaata aacatctttt ttatacgcaa atacatacaa tccggtcggc
    39121 aaataggcga agtgctccat cgcttccgaa acggtgaaga tggcgttttt agcattatat
    39181 tcatcaccgg tcaccggttt accgttctta aatagagaga acatcaggtt ctcgctgtcc
    39241 atcgccagcg attttgacag taaagaaaaa cgctccagac caagcaaaaa tatcagacta
    39301 cgattgtgag ttaccggata gaggtaatag acgaaggttt taccgtcaaa agagataaac
    39361 cctgtatttt tgacatgtcg atacttcaca acctgcataa tatctgcaca ataatttttc
    39421 tcgaactcct ttacctgaat acattcgtca ctggaaatca gataaggacc gacatcgtac
    39481 aaataagagg gggaaaccga gtcggcgtaa gctgtgcgca aaccaaccaa cagctgttcc
    39541 tccgtgggat ttagcgtgtt gataagatca attgccacgc tacgccgata ttcagcaata
    39601 tttgccaccg caaaagcagt atcaataacg gactgtttca ggctatacac ccgttccttt
    39661 accatttgag tgtagatccc gcaggcaact gctgaaatca tgataaaaat cagcagactg
    39721 actgtaagta cgaacttatt gattctggac atacgtaaac tactctttta ctaattttcc
    39781 acttttatcc caggcggaga atggcatggg tttctggtac agatacccct gagcctgaac
    39841 acatcctaat ttgattaatt cgcgcgcaac gtcttcgctc tctacgcctt ccgcaatcac
    39901 cgggatccgg ttatagcgtg ccaggtcgaa aataatgcgc acaatttttc ccgcagtacc
    39961 gaaaatatcg ccggtgaatt gcgagtccac ctttatgctg tctggattaa tttcataaaa
    40021 acgtttcagg tttgacaaac cggtgccaaa gtcatcaatc gatatccgta ccccttgttt
    40081 acgcagttgt tcaatattga gataaaaatg ttcattaatt cgctcgatca cggtttcagt
    40141 gatctcaaca cagaggctgt tcgccttcag gccattttct ttcatgatgg tggtaaaacg
    40201 ctcatgaaag tgtggttcgt ttaactgcca gggcgaaaca ttaatatgca gtaagaaatc
    40261 atccttcagc gacgcacgct gactaaaatg tctgaattca cccattgccg ttttaataat
    40321 ctgataaccc agctcattga taaacccgat atcttcagca atggtaatga acttcagcgg
    40381 tgaaatgatc ccccgctccg cagacaccca acggcacaac gcctccgcgc ccagaatggc
    40441 gcgggtgtta atatcaacga tcggttgata gacgaggaat agttcgccaa tttccattgc
    40501 atggcgaata ttacgcgcaa tccagatatt ctcttctatt tcgttgagtt tcgcgtcatc
    40561 acagaaaata aactctgaga acatatggtc acggatactg gaaatcgcca gtttcagttt
    40621 ttctgcgtaa ctccaggcgt tttccccctg caaaggttca caaatggcag acttatggat
    40681 gcgcagattg cggtagccaa agctgctgtc aaaatcgttt accatcgcta ttttacgggt
    40741 aaatgtctgt acattttccc gacacagaag taaatagaga tcggcattga atgtcacgat
    40801 atcgcagcat tgcgcatatt tctcggcaat tcgctgacac aatttcctga cgattttatt
    40861 gcgctcatca acaccaaaca ccgcttccac ggcttccaga ccacacagtt tgatgatccc
    40921 cacagccaga tactgattat tgttagactc aataatcgcc atatttttaa taaaaccact
    40981 ttcctgatcg taagagatca gtgagagcaa tttatttgac cgttcaattt cggcatcttt
    41041 catttccgcg atcgaatttt tgatgctgat aatctctttc gcatcgcctt cacgaatttt
    41101 cagagcctcg atttgatccg ttgagtcagg caaaaacgcc agcgtattaa ccagctctgt
    41161 catttcagaa aattgccgac ggaacacacg agtggtcatt aaataaacca ccagcaatac
    41221 gataataatg aacgcaaacg gcagataaaa aagtttatct gatgcgttca ataaattacc
    41281 gccaggataa taaaaataga tttcgaataa tgcgttgttt ggcaccgctg atgttttttc
    41341 gatatattca gtatcgacag aatcaataat attataatta tcttcgctat tataaataat
    41401 cagtttttca cgagcgagtt gattcttggc aatgatctca tggccttgtt tcaaaaatag
    41461 aacttcatca ttagcgctga tttgatcaag atactcgttc agatatcgcc agtttaaatc
    41521 gacatgaatt ttatccaccg ctaacaaatc gtgatctttg ccgttgatgt gtagcgtaaa
    41581 agagatacat tttttacccg gacgatcaaa gcaattgtat gccggattcc agctgttgtt
    41641 agagtcatct gaagccaccg accacggtcg tttcgatggg ttaaaatcgg caaaaataac
    41701 ccgccctgac tcgtcgacaa gcggtccatt tacttgttcc tgatgataaa caacgatttt
    41761 atcattcgcc ctccgcgaaa aaagataata tttattatca tcaagtacca gtcccaccga
    41821 gtctaaaaat ggcatcattt ccattttaag aatcacggcg cgttgaatct cctctgtatt
    41881 ttttaataaa tacagtgagt cctttaatgt cagggccgaa cgttcaatat ctttaaagaa
    41941 atagccaacg tttttctgaa taagttcaaa gcggctatcg gcacgtttta ccgcgcgctc
    42001 cgataccagt tgatagttaa tgatgaaaaa aagaccaata aatgacagtg ctgccaataa
    42061 aaataaaatt atcagcctta tctttatctt ttcgtataaa ctcagcatgt taatacattt
    42121 aacaaaataa ctatctgaac gctgtgccgc tgcaaaaatt gtcccttgct gcggcttttt
    42181 aaccaaatta cccgattcta caaaatcagc agaaagttac aacacttgct tagggcaata
    42241 atttcctgtg aggtgattac cctttcaagc aatattcaaa cgtaactatc ctttaatttt
    42301 cggatccagc gcatcgcgta aaccatcgcc caacaaattg aacgccagta cggtcagaaa
    42361 aatagccagg gccggaaaaa cagcgacatg cggcgcgata accatatccg ctcgagcctc
    42421 attgagcatt gctccccact ctggtgtcgg cggctgcgca ccgaggccga gaaatgagag
    42481 gctggcggca gagataatcg aggtaccaat gcgcatggtg aaaaacacca cgatagaaga
    42541 gacggtccca ggcaggatat gacgcaacaa aacggtcata tcgctggcac caatactgcg
    42601 tgctgactca ataaaggttt gctgtttcaa caccagcgtg ttgccgcgca ccaggcgggc
    42661 aaacgcgggg atggaaaaaa tggcgactgc aataatcacg ttagcaatgc cgcttcccaa
    42721 caccgcaaca acagcgatcg ccagtaaaat acccgggaag gcaaacagca catcgcaaat
    42781 gcgcatgatc agccgatccc accagccttc ataatatcca gcgagcaagc ccagcaacgt
    42841 cccgatcgcc gcaccgataa acacggcaaa cacgcccgcc gccagcgaga tttgcgcacc
    42901 aaccaggaca cggctgaaaa tgtcacgccc cagtgaatcg acgccaaacc agtgctgcaa
    42961 agaaggtccg ttattcagat tgtcataatc aaaataattt tcggcgtcat agggagcgat
    43021 ccagcgtgca aaaatggcca ccacaatcaa taaaataacg aataatgcgg cggtcatcgc
    43081 catatgctga cggcgaaatc gtcgccagaa ttcatgccac ggtgtacgta cctggtcagg
    43141 tttgaccagt ggcatggcgt ttaacaccgc ctgacgtcgc cagttaaata gtcgcatcct
    43201 tacttgtacc tgatagccgg gttaatggcg gcgtaaagca catccaccac taagttgata
    43261 agaataaatt ccagcgagaa aagcagaatt tccgcctgaa tcaccgggta atcacgcatt
    43321 tctacggagt caacgagtaa gcgtccaagt cccggccagt tgaaaacttt ctccacaacg
    43381 atggaaccac cgagcaaaaa gccaaactgt aagcccatca tggtcactac cgggatcatc
    43441 gcgttacgta gcccgtgttt gaggacaacc caggtttcgc tcaccccttt cgccctcgcg
    43501 gtacgcatat aatcttcgct taaaacatcg acaaacgacg cgcgggtaaa gcgcgccatc
    43561 acggcggcca ctgccgcgcc gagcgtcagg gagggtaaaa tgtagtgctg ccaactgtct
    43621 gctcccacgg taggcagcca gcccagttca acggagaata cctgaattaa aagcatcccc
    43681 agagcaaatg ccggaaacga gatccccgac accgcaatgg tcatactcaa tcgatccggc
    43741 caacggttac gccagacggc ggcgataatt cccgccgcca taccaaatat aaccgcccag
    43801 accatactgg ttatggtcag ccacagcgtt ggcataaagc ggctggcaat ctcatcggca
    43861 accggacgac gcgacaccat cgacaggcca aaatccccct gcacagcatt gctgatatag
    43921 tgccagaact ggtgatacag cggctgatcc aaccccagct gctgacgcac cagttctata
    43981 acctgcgcat cagcttcggg cccggcaatc aatcgcgccg gatcgccggg cagcatatgg
    44041 acaaataaaa acaccagcac cgagacgata aacagcgtcg gaatcaaccc cagtaagcgt
    44101 ttgataacgt aattaagcat tccactccct gcgttgctta ttgcaaatcc gcgtcttcaa
    44161 agctgaagcc ggtgtctggc atgatccaaa aaccggtcag gtttttactg tgtgccgaca
    44221 ccagtttttc taccaccagc gggatccacg gcgattcttg ccagatgata tcctgcgccg
    44281 ccttatataa gcgggtcttt tccgccggat cattagtttt cagtgcctga gccaggaagt
    44341 catccacctg tttattgctg taaaacgcgg tattaaacag cgtcggtggc cagttctgcg
    44401 aggcaaacag cggcgatagt gcccagtccg cttcgccggt tgaagccgac cagccagtgt
    44461 agaacatccg cacgccgctc tctttttgcc ctttaccttc aacttctgcc gcccgctgtc
    44521 cggcatccat cgcagtcacc tgggctttaa tcccgacctg cgctaactgc tgctgggtaa
    44581 attgcagcac tttctgcgcg gtgctgtggt tatgtgacga ccacagcgtg gtactgaaac
    44641 cgttgggata tcccgcctct ttcagtaatt cgcgcgcttt cactggatcg taaggccacg
    44701 gtttataact ttgcgcgtag gcgatacttg gcggtaccac accagtagct ggcgttgcat
    44761 agcccgcaaa ggcaactttc accagcgccg gacggttaat ggcgtaattc agcgcctcac
    44821 ggaccttcgg gttatcgaac ggcttttgcg tcacgttcat actgatataa cgctgcataa
    44881 ttgacggact ggccatcaac tcgatatttt tgtttttctc cagcagtgtg gcctgctcgt
    44941 aaggaatggg gaaagcaaac tgcgcttcac cggtttgcag cattgccgcg cgggtgttgt
    45001 tatccgccac cggacgccag gttatgctgt ccagtttggg caatcctggc tgccagtaac
    45061 ccgcgaattt tttcaccttc acaaaatcgg tctgattcca ggtatccagt tcatacggtc
    45121 cggttcccac cggataaaaa ccaatctcct tgccatattt ttccagcgct gccggtgaaa
    45181 tcatcgcggt cgccggatgg gcaagaatat taataaacgc tgagaacggc tgtttgaggg
    45241 taatctttac cgttgtcgga tcgatcgctt ccgttttagc aatattctta tacaggttat
    45301 agcgtttaag atgattcgcc ggatcgctgg cccggtccag attcgctttc accgccgcgg
    45361 cgttgaaatc ggtgccatcc tggaatttaa tgccttcccg caatttcacg gtgtaagtaa
    45421 tgccgtcatc ggaaacggta taactctccg ccagcacgtt tttcagtttc atctctttat
    45481 ccagaccgaa cagcccctgg taaaacgatt tcgctacggc ctgagataac gtgtcatttg
    45541 cgtcatacgg atcgagcgtg gtgaaattcg atcctaccgc caccaccaca tctttggcag
    45601 cgaatgcaca agatgccatc aacgctgtcg caattcccag cgccactaac ccactacggt
    45661 gtacagctct tgccatttta ttctccgcct gaatgttatc tacgcatgaa tgcgtattct
    45721 gattgtggtt gtgcgacgta atgccccggc ccgacgcatt gcaacgagac ggctgccacc
    45781 tcttcgccac gcagatgaat attgctggga agatcgtccg acagcagtac acgctgcggt
    45841 cgttgtcggg acggttcagc gaccggaact gccgccagta atttacgcgt ataaggatgc
    45901 tgcgggtttt cgaagaccgc gcgccgtgga ccaatttcaa caatttgccc gagatacatc
    45961 accgccacac gatgactaat ccgctctacc accgccatat cgtgggagat aaacagatac
    46021 gcaatgccga aatcacgctg gagatcgagc aacaagttga taatctgccc gcgaatagaa
    46081 acatccagcg ccgaaacggc ttcgtcggca atgatcactt ttggattcaa tgccaacgcg
    46141 cgagcaatgc agatgcgctg gcgctgaccg ccggaaaact catgcgggta acgccaggca
    46201 tgttcaggta acaggcccac gcgctccagc aaccacgcaa cgcgtgcagc cgcgtcttta
    46261 cctggcaata aaccgtgtac acgcagcggt tcgataatcg aatcaccgat ggtctgacgt
    46321 gggtccagcg aagcgtaagg gtcctgaaaa ataaactgaa tatcccggcg taatgcctga
    46381 agtttgccgg gtgacaaggt atcgattcgc tgaccgttaa agataatttc gccgccctgc
    46441 gattcgacca ggcgcagcaa cgcccgcccg gtagtggatt taccgctgcc agactcgccc
    46501 accagcgata gcgtttcgcc aggccagaga tcaaaactga ctttctcaac ggcatgcact
    46561 tcccgcgtta cgcgattcaa caaaccgctg cgcaaaggga aacgggtgac aagattacgc
    46621 actcgtaaaa caggttcgcc atccaccacc gttttctgct cgatgggggg ggcctgtttc
    46681 gctggatgtt caagcgatat caacgggaaa cgtcggggat aatctaaccc tttcatcgca
    46741 ccaagttgcg gaacagcagc taacagcgca cgggtgtaag gatgttgcgg tgcatgaaaa
    46801 atctgttcga cggtacccgt ttccaccgcc tcgccctgat acatcaccag tacccgatcg
    46861 gcaatctctg ccaccacgcc catatcgtga gtgataaaga taacgcccat cgacatctct
    46921 ttttgcaata ctttgattaa ttgcaggatc tgcgcctgaa tagtgacatc cagcgcggtg
    46981 gttggctcat cggcaatcag caccgccggg cggcatgaca gcgccatcgc aatcatcact
    47041 cgctggcgca tcccgccaga gagttgatgc ggataacgtg aaagaatggt ttgtgcctca
    47101 ggaatgcgta cctgatccag catccgcttc gcctcgacca tcgcttcttc acgactggcg
    47161 ttctgatgca gacgaattga ttcggcaatc tgttcaccca cagtaaatac cgggttcagc
    47221 gatgtcatcg gctcctgaaa tatcatcgcc atatccgcac cgcgaacatg gcgcatttgt
    47281 gcagcgttct gctcgctaag ttcaatcact tcgcgactgc gccgctgcaa cagcatttta
    47341 tcgcactgta ctaaaccgcc cgcctgttcc aacaggcgca tcaatgccaa cgcagtcact
    47401 gacttaccgg agccggattc gccaacaatt gccagcgtct caccgcgttg cagactaaaa
    47461 gagagattgc ggaccgcagc tattttctgc tggtcctgca taaaggcaat attcagattt
    47521 tcaaccgcca gcacattacc ggcatcaagt tcatcactgt gtggcaacgg tgtccccttt
    47581 ttcacggtag ataccggtgg ttggcgtatc gcctgcgtag ccccaggcgc gatacattcc
    47641 ttcggtgtta aacggtagcg cgacattccc ttcatggtcg atagcgatta agccaccgct
    47701 accgccaagc gcagggagtt tttccattac tacccgctcg caggcttccg cgagacttaa
    47761 tccgccgtaa tccattaacg cggcgatgtc atatgccgcc agcgcgcgga tgaagacttc
    47821 gcccgtgccg gtacaagaaa ccgccacact ggcgttattg gcgtagcatc cggcacccac
    47881 taagggacta tcgccaactc gtccgggtaa tttattggtc attccgcctg tggacgtggc
    47941 tgccgccaaa ttgccgtcta aatccaacgc cacggccccc acggtgccca ttttctgttt
    48001 ttcatccagt ggcgcaccgc tatggtcgag gacggttgcc ccttccttgc gcgctgccag
    48061 tagttgttca taacgcaaag gcgtggagaa aatctccggc gagacgcgct ccatgccacg
    48121 agcaaacgca aaattttctg ccccttcgcc aatcatcatc acatgcgggc tttgctccat
    48181 caccagccgg gcggcaagaa ccggattacg cagatgacta acgcccgcca ccgcaccggc
    48241 tttcagggtg ttaccatcca tcacacaggc gtccagttca tgggtttcat cacgcgtaaa
    48301 gacagcgcca attccggcgt taaacagtgg acactcttcc agcagacgca ccgcttccgt
    48361 caccacatcc agcgcacttt cgcccgcttc cagcattttc tgcccggttt caacaatggc
    48421 agacaacgcc tcgatgtagc gtaattcctg ttgcagactc atctgcgcgc ggctaattgc
    48481 acctgcgcca ccatgaattg caatgactgc tttgcccata gtattcgtcc attaagggtg
    48541 gttcgccact tttgctataa atatcagaat ttttatgaat tactcattca atttttgaat
    48601 atagaaagat ggatatggca tgtaaaggca ggacccagcg ctacgcccga ggtggcatac
    48661 agtctgtggc gtttttctga cataataggc aaattcgatt ttgcctccgc aggagtgttt
    48721 tcatggaatt taccaccgga ttgatgtcgc tcgacaccgc gcttaatgag atgctttctc
    48781 gcgtcacccc actgaccgcc caggaaacgc tgccactggt acagtgtttt ggtcgtattc
    48841 tggcgagcga tgtcgtttcg ccgcttgatg ttccggggtt tgataactcc gcaatggacg
    48901 gctacgcggt gcgtttagcc gatattgcct ccgggcaacc gctgcccgtt gccggtaaat
    48961 cctttgccgg tcagccatac catggtgaat ggcctgcggg tacctgcatt cgtattatga
    49021 ccggtgcgcc ggtgccggaa ggctgcgaag cggtggtgat gcaggagcag actgaacaaa
    49081 tggacaatgg cgtgcgtttt actgctgaag tgcgtagcgg gcaaaatatt cgccgtcgcg
    49141 gtgaagatat ctctgcaggt gcggttgttt tcccggcggg aactcgcctg actaccgcag
    49201 agctgccagt aattgcttca ctggggattg ccgaagttcc ggtgattcgt aaagtgcgtg
    49261 tagcgctttt ttctaccggt gatgaactcc agttgcccgg tcagccgctg ggcgacggcc
    49321 aaatctacga taccaaccgt ctcgccgtac acctgatgtt agaacagttg ggatgcgagg
    49381 taattaactt agggattatc cgcgacgatc cccatgccct gcgcgccgca tttattgaag
    49441 ccgacagcca ggcggatgtg gtgatcagtt ccggcggtgt ttcagtgggt gaggcggatt
    49501 acaccaaaac gattcttgaa gagctggggg agatcgcctt ctggaagctg gcgattaaac
    49561 caggtaaacc gttcgcgttc ggtaaactca gcaatagctg gttctgcggc ctgccgggca
    49621 acccggtttc agcgacgctg accttctatc aactggtaca gcctttgctg gcaaaactaa
    49681 gcggtaacac cgccagcggc ctgcccgcgc gccagcgcgt acgcacagcg tcccgcctga
    49741 aaaaaacgcc aggacgtctt gatttccagc gcggcgtgct gcaacgcaac gccgatggcg
    49801 aactggaagt gacgaccacc ggacatcagg gttcacatat atttagctcc tttagcctcg
    49861 gcaactgctt tatcgtgctg gaacgcgatc gcggcaatgt ggaagtgggc gaatgggtgg
    49921 aagtagaacc gtttaacgcg ttgttcggag gcctgtaatg gcggaactca gcgatcagga
    49981 gatgctgcgc tacaaccggc aaatcattct gcgcggcttt gattttgacg gccaggaggc
    50041 gctgaaagat tctcgcgtgc tgatagtggg cctgggcggc ctcggctgtg cagcctcgca
    50101 gtatctggca agcgccggtg tcggtaacct gacgctgctc gacttcgaca cggtttcgct
    50161 ctcgaatctg caacgccaga cactgcacag tgatgccacg gtcgggcaac cgaaggtgga
    50221 atccgcccgt gacgccctga cgcggatcaa cccacatatc gcgattacgc cagtcaatgc
    50281 actgctggat gacgcagaac ttgcagcatt gattgctgaa cacgatctgg tgctcgactg
    50341 tacggataac gttgcggtac gtaatcaact gaacgcaggc tgttttgccg cgaaggtacc
    50401 gctggtttcc ggcgcggcaa ttcgtatgga aggtcaaatc accgtcttta cttatcagga
    50461 cggtgaaccg tgctatcgct gccttagccg tttgtttggt gaaaatgcat taacctgcgt
    50521 ggaagcaggc gtaatggcac cgttgatcgg cgtaattggt tcgttgcagg caatggaagc
    50581 gatcaaaatg ctggcaggtt atggcaaacc ggccagcggg aaaatcgtca tgtacgatgc
    50641 gatgacctgt cagtttcgcg aaatgaaact gatgcgtaat ccggggtgtg aggtgtgtgg
    50701 gcagtaattg ccacctccag gcctgataag acgcggcact ccgccacgtc atcagcaatt
    50761 tatgaggatg cagaacgtcc ggttaaatcg acgttctgcc aaacgctccc tgccagtcct
    50821 gctcaaactt cgccacagcg gcatcaaccg ccggatagct aatcatctgt tgtgccacat
    50881 ccagtggcag agtaattgat tcacatcctg ccagtaagca gtccagcgcc tgacgcgggg
    50941 ttttgaaact cgctgccagc actttcgcct gcggcgcatg cattttcaat aactggtgta
    51001 agtcggtcac agtctgaatg ccgctaccgc cctgagcatc aatacgatta acgtaaggcg
    51061 caacatattc cgcacctgcc agcgccgaca gcagcccttg tgctgcgcca tataccgcgg
    51121 ttcccagcgt cggaatccct tccgctttta acatcttaat agctgccagc ccctcggcgg
    51181 tcaccggaac tttcaccacg atatccgcaa taatagaacg cagcttaagc gcgtcattaa
    51241 ccatcccttc ggcagtggta gccattacct gggcaaacag acgcccctga ccgcccatcg
    51301 cttcatgaag ttgcggaagc acaacatcca gcggtttttt acccgcggcg ataatgcttg
    51361 ggttagtggt cacacccgcc agcggaaaaa tacgtgacag cgccttcacc gcaacaacgt
    51421 ctgaagtatc cagatacagt tccataacca tcctcaaaat gtactttttg tctgaatgta
    51481 gactatcacg ggaaaactct ctgaacagtt gacgcacatc aatctaactt tcattcgaaa
    51541 gtattttaat gcttgaacga aatagagagg caactatgat tttcaatatt cagcgctact
    51601 cgacccatga tggccccggt atccgcacgg tcgtatttct taaaggctgt tcgctgggct
    51661 gccgctggtg tcagaacccg gaaagccgcg cccgcacgca ggatctgctg tatgacgcac
    51721 gactgtgtct ggaaggctgc gagctgtgcg ctaaggccgc gccggaagtg attgagcgcg
    51781 cgctgaatgg tttgcttatt catcgggaaa agttaacccc ggagcatctg acggcgttaa
    51841 ccgactgctg tccgacacag gcattaaccg tgtgtggtga agtgaaaagc gttgaggaga
    51901 tcatgacgac cgttctgcgc gataaaccgt tttacgatcg cagcggcggc ggtttaacgc
    51961 tttcgggtgg tgagcccttt atgcagccgg aaatggcgat ggcgctactg caagccagcc
    52021 acgaggcagg cattcatact gcggtagaaa cctgtctgca tgtgccgtgg aaatatatcg
    52081 ccccttctct gccctatatc gatctgtttc ttgccgattt aaaacacgtt gccgacgcgc
    52141 cgtttaaaca gtggaccgac ggtaacgccg ccagagtgct ggataacctg aaaaaactcg
    52201 ccgcagcggg caaaaaaatc attatccgcg tgccgctgat tcagggcttt aatgccgacg
    52261 aaacctctgt aaaagccatt accgattttg ccgccgacga gctgcacgtt ggcgaaattc
    52321 attttctgcc ctaccacacg ctgggcatca acaaatatca cttacttaat ctgccctatg
    52381 acgccccgga aaaaccgctt gatgcgccag aactgctcga ctttgcccag cagtatgcct
    52441 gccagaaagg gttaaccgcg accttacgag gataacaacc atgaccacac tgaaactgga
    52501 cacgctcagc gaccgcatta aagcgcacaa aaatgcgctg gtgcatattg tgaaaccgcc
    52561 agtctgtacc gagcgcgcgc agcactatac cgagatgtat caacaacatc tcgataagcc
    52621 gatcccggta cgtcgcgcgc tggcactggc gcatcacctg gcgaatcgca ccatctggat
    52681 caaacacgat gagttgatca ttggcaacca ggcaagcgaa gttcgcgccg cgccgatctt
    52741 cccggaatat actgtctcgt ggatcgaaaa agagattgat gatctggcag atcgtcccgg
    52801 tgctggcttt gcggtgagcg aagagaacaa acgcgttctg catgaagtgt gcccgtggtg
    52861 gcgcggtcag accgtacagg atcgctgcta cggcatgttt accgatgagc aaaaaggtct
    52921 gctggcgacc ggaatcatta aagcggaagg caatatgacc tccggcgatg cgcacctggc
    52981 ggtgaatttc ccgctgctgc tggaaaaagg gcttgatggt ctgcgcgaga aagtagcgga
    53041 acgtcgctcg cgcatcaacc tgacggtgct ggaagattta cacggtgagc aattcctgaa
    53101 agcgattgat atcgtgctgg tggcagtcag tgaacacatt gaacgtttcg ctgccctggc
    53161 gcgtgaaatg gccgcgaccg aaacccgcga aagccgtcgc gatgaactgc tggcgatggc
    53221 agaaaactgc gatcttatcg cccaccagcc gccgcagact ttctggcagg cgctgcaact
    53281 gtgttacttc atccagttga ttttgcagat cgaatctaac ggtcactcag tatcgtttgg
    53341 tcgtatggac cagtatctct acccgtacta tcgccgcgac gttgaactca accagacgct
    53401 ggatcgcgaa cacgccatcg agatgctgca tagctgctgg ctgaaactgc tggaagtgaa
    53461 caagatccgc tccggctcac actcaaaagc ctctgcggga agtccgctgt atcagaacgt
    53521 cactattggc gggcaaaatc tggttgatgg tcaaccaatg gacgcggtga atccactctc
    53581 ttacgcgatc ctcgaatcct gcggtcgcct gcgttccact cagcctaacc tcagcgtgcg
    53641 ttaccatgca ggaatgagca acgatttcct cgacgcctgc gtacaggtga tccgttgcgg
    53701 cttcgggatg ccggcgttca acaacgacga aatcgtgatc ccggaattta ttaaactcgg
    53761 tattgaaccg caggacgctt atgactacgc agcgattggt tgtatagaaa ccgccgtcgg
    53821 tggcaaatgg ggctatcgct gtaccggcat gagctttatc aacttcgccc gcgtgatgct
    53881 ggcggcgctg gaaggcgggc atgatgccac cagcggcaaa gtgttcctgc cacaagaaaa
    53941 agcgttgtcg gcaggtaact tcaacaactt cgatgaagtg atggacgcgt gggatacgca
    54001 aatccgttac tacacccgca aatcaatcga aatcgaatat gtcgtcgaca ccatgctgga
    54061 agagaacgtg cacgatattc tctgctcggc gctggtggat gactgtattg agcgagcgaa
    54121 aagtatcaag caaggcggcg cgaaatatga ctgggtttct ggcctgcagg tcggcattgc
    54181 caacctcggc aacagcctgg cggcagtgaa gaaactggtg tttgaacaag gtgcgattgg
    54241 tcagcaacag cttgctgccg cactggcaga tgacttcgac ggcctgactc acgagcagct
    54301 gcgtcagcgg ctgattaacg gtgcgccgaa gtacggcaac gacgatgata ctgtcgatac
    54361 gctgctggct cgcgcttatc agacctatat cgacgaactg aaacagtacc ataatccgcg
    54421 ctacggtcgt ggtccggttg gcggcaacta ttacgcgggt acgtcatcaa tctccgctaa
    54481 cgtaccgttt ggcgcgcaga ctatggcaac accggacggg cgtaaagccc acaccccgct
    54541 ggcagaaggc gcaagcccgg cctccggtac tgaccatctt ggccctactg cggtcattgg
    54601 ctcagtgggt aaactgccta cggcagcgat tctcggcggc gtgttgctca accagaaact
    54661 gaatccggca acgctggaga acgaatctga caagcagaaa ctgatgatcc tgctgcgtac
    54721 cttctttgaa gtgcataaag gctggcatat tcagtacaac atcgtttccc gcgaaacgct
    54781 gctggatgcg aaaaaacatc ccgatcagta tcgcgatctg gtagtgcgtg tcgcgggcta
    54841 ttccgcgttc ttcaccgcgc tctctccaga cgctcaggac gatatcatcg cccgtactga
    54901 acatatgctg taatctcctc ggcccggcgg cgtcgtcgcc gggctaaatc attcacatca
    54961 tcaatttcat ccttactttc attcgaaata taatttgtgc tctgcgtcac attgttatta
    55021 cactgttacg gtttcatttt cgagccagga gcacacctat gagcgtaaaa gttatcgtca
    55081 cagacatgga cggtactttt cttaacgacg ccaaaacgta caaccaacca cgttttatgg
    55141 cgcaatatca ggaactgaaa aagcgcggca ttaagttcgt tgttgccagc ggtaatcagt
    55201 attaccagct tatttcattc tttcctgagc taaaggatga gatctctttt gtcgcggaaa
    55261 acggcgcact ggtttacgaa catggcaagc agttgttcca cggcgaactg acccgacatg
    55321 aatcgcggat tgttattggc gagttgctaa aagataagca actcaatttt gtcgcctgcg
    55381 gtctgcaaag tgcatatgtc agcgaaaatg cccccgaagc atttgtcgca ctgatggcaa
    55441 aacactacca tcgcctgaaa cctgtaaaag attatcagga gattgacgac gtactgttca
    55501 agttttcgct caacctgccg gatgaacaaa tcccgttagt gatcgacaaa ctgcacgtag
    55561 cgctcgatgg cattatgaaa cccgttacca gtggttttgg ctttatcgac ctgattattc
    55621 ccggtctaca taaagcaaac ggtatttcgc ggttactgaa acgctgggat ctgtcaccgc
    55681 aaaatgtggt agcgattggc gacagcggta acgatgcgga gatgctgaaa atggcgcgtt
    55741 attcctttgc gatgggcaat gctgcggaaa acattaaaca aatcgcccgt tacgctaccg
    55801 atgataataa tcatgaaggc gcgctgaatg tgattcaggc ggtgctggat aacacatccc
    55861 cttttaacag ctgacctctc taccggagcc gtgcgctccg gttttccctt ctttttacat
    55921 cctgtacatc acatcaaatc attaaacttg cattaactta tttataactt atattgtcac
    55981 atgcaaatca gaatggtttc gaatgaaagt taatgagagg tggttatggc ttctactttt
    56041 accagcgaca cattgcctgc cgatcacaaa gcagctatcc gtcagatgaa gcacgcgctg
    56101 cgggcgcagc ttggcgacgt ccagcagatc tttaatcagc taagcgatga cattgccacg
    56161 cgagtggctg aaatcaacgc actcaaagca cagggcgatg ccgtctggcc ggtgctgtct
    56221 tatgccgata tcaaagcagg tcatgttact gcagagcagc gcgaacagat taaacgtcgc
    56281 ggttgtgcgg tgataaaagg ccatttcccc cgcgaacaag cgctaggctg ggatcagtcg
    56341 atgctggact atctggaccg caaccgcttt gacgaggtct acaaaggccc cggcgataat
    56401 ttcttcggga cgctcagcgc ttcacgtccc gagatttacc ccatctactg gtcgcaggcg
    56461 caaatgcagg cccgccagag tgaagaaatg gcgaatgcgc agtcgtttct caatcgtctg
    56521 tggacatttg aaagtgatgg aaagcaatgg tttaacccgg atgtgagcgt catctaccct
    56581 gaccgtatcc gccgccgtcc gcccggaacg acctccaaag gtcttggagc gcataccgac
    56641 tccggggcac tggaacgctg gctgcttcca gcgtatcagc gcgttttcgc caacgtcttt
    56701 aatggcaatc tggcgcaata tgatccctgg catgcggcac atcgtacgga agttgaagag
    56761 tacacggtgg acaacaccac caaatgttcc gtgtttcgga cattccaggg ctggacagcg
    56821 ctctctgata tgctgcctgg tcaggggctg ctgcacgtcg tgcccattcc tgaagctatg
    56881 gcgtacgtac tgttacgtcc gctgcttgat gatgtgccgg aggatgaact gtgcggcgta
    56941 gcgcccggaa gagtattgcc ggtatcagag caatggcatc cactgttgat tgaggcgtta
    57001 accagcattc caaaactcga agccggagac tccgtctggt ggcactgcga cgtcatccat
    57061 tccgttgccc ccgttgaaaa tcaacaaggt tggggcaacg tgatgtacat tcctgcggca
    57121 ccgatgtgcg agaaaaatct tgcctacgcg cacaaggtga aggccgcact ggaaaaaggc
    57181 gcatcgccgg gcgacttccc gcgcgaggac tatgaaacaa actgggaagg acgctttacg
    57241 cttgccgacc tcaacattca cggtaagcga gcgttgggca tggatgtttg agaattaatg
    57301 gaagtgaatt gatgtgggat taagaaaatc gattcgacgt tactcagatt gctgacaaat
    57361 gcgctttgtt aatgcctgat gcggcgttaa cgccttatcc ggcctacaaa gtcctgcaga
    57421 ttcaatatat tgcaggtact gcgtaggcct gataagcgta gcgcatcagg ctattttgca
    57481 tttgtcatca gccgccgtca ccccgacagt atcggggtga cggataatca cttactcgat
    57541 ccctttacta cgcaggtaat cttcgtaatt accgctaaag tcgatcacgc gttccggggt
    57601 gatttccaga atgcgggtcg ccagggagct tacgaactca cggtcgtgtg aaacaaagat
    57661 cagcgtgccc tgatacagtt ccagtgccat gttcagcgac tcaatggatt ccatatccag
    57721 gtggttggtc ggttcgtcca tgatcagaat gttcggcttc tgcatcatta acttaccaaa
    57781 cagcatccgc cctttttccc caccggaaag cactttagct ggctttttga tgtcgtcctg
    57841 gctgaacagc aaacgaccga gaatactgcg taccgcctgc tcgtcatcgc cttcctgctt
    57901 ccactggctc atccattcga acacggtcag atcattttca aactcatatt cgtggtcctg
    57961 agcatagtaa ccaatgcgcg cgttctcaga ccattttacg gtgccgctgt ccggttgcag
    58021 atcgcccacc agcgttttca gcagcgttga tttaccgacg ccgttggtac ccagtaccgc
    58081 cagtttttca cccacttcca gcagcaggtt gagattttta aacagcggac cgttatcaaa
    58141 ccctttggtc agaccttcca cttccagcgc gttacggaac agtttcttat cctgttcaaa
    58201 acggatgaac gggttctgac ggctggaggc tttcacctct tccagtttga ttttatcaat
    58261 ctggcgcgcg cgcgaagttg cctggcgaga tttcgaggcg ttggcgctaa agcggctaac
    58321 gaaagattgc aactcagcaa tctgcgcttt cttcttggcg ttatcggcca gcagacgttc
    58381 acgcgcctgg gtcgccgccg tcatgtactc atcgtagtta cccggataaa cgcgcagctc
    58441 gccgtaatcc agatccgcca tgtgggtaca gaccatgtta aggaagtgac ggtcgtgcga
    58501 gatgatgatc atggtgctgt cacgctcgtt cagcacctgt tccagccagc gaatggtgtc
    58561 gatgtcgagg ttgttggtcg gttcgtcgag caggagaata tccggatcag caaacagcgc
    58621 ctgcgccaga agcacacgca gcttccagcc aggagcaact tcactcatcg ggccgtagtg
    58681 ctgttccact ggaattccca cgccaagcaa cagttcaccg gcgcgagctt ccgcagagta
    58741 accgtccatt tcgccgtatt taacttccag atcggccact ttatagccgt cttcttcact
    58801 catttccggc aaagcataga tgcggtcgcg ctcctgcttc acttcccaca actctttatg
    58861 ccccatgatc accgtatcca gcacagtgaa ctcttcaaag gcaaactgat cctgacgcag
    58921 tttaccaatg cgctcgttgg gatcgaggga aacgttaccc agcgtcggct caaggtcgcc
    58981 gccgaggatc ttcataaagg tggatttacc actaccgttc gcgccaatca ggccgtaacg
    59041 gttgccgccg ccaaatttga cggaaatgtt ttcaaacaac ggcttactgc cgaactgcat
    59101 ggtgacgtta ctggaaacta acacaggcgt atcctgaaaa gagatatgac aaaccgcgca
    59161 ttatgccata agtctgaaag aagatcctgc tcctcgctta aggtctacac tcaagccaaa
    59221 ggcaaaaaat gtgatttcgt acacatctga tttcactgtg agctggaatg aacttataat
    59281 gcgcttccaa tactctaata ttctcaaccc aatggcctgc caggcacaaa atctcgctta
    59341 acatgaatat gaaattgaaa acattattcg cagcggcctt cgctgttgtc ggcttttgca
    59401 gtaccgcctc tgcggtaact tatcctctgc caaccgacgg gagtcgcctg gttggtcaga
    59461 atcaggtgat caccattcct gaaggtaaca ctcagccgct ggagtatttt gccgccgagt
    59521 accagatggg gctttccaat atgatggaag cgaacccggg tgtggatacc ttcctgccga
    59581 aaggcggtac tgtactgaac attccgcagc agctgatcct gccggatacc gttcatgaag
    59641 gcatcgtcat taacagtgct gagatgcgtc tttattacta tccgaaaggg accaacaccg
    59701 ttatcgtgct gccgatcggc attggtcagt taggcaaaga tacgcctatc aactggacca
    59761 ccaaagttga gcgtaaaaaa gcaggcccga cctggacgcc gaccgccaaa atgcacgcag
    59821 agtaccgcgc tgcgggcgaa ccgcttccgg ctgtcgttcc ggcaggtccg gataacccga
    59881 tggggctgta tgcactctat atcggtcgcc tgtatgctat ccatggcacc aacgccaact
    59941 tcggtatcgg cctgcgtgta agtcatggtt gtgtgcgtct gcgtaacgaa gacatcaaat
    60001 tcctgttcga gaaagtaccg gtcggtaccc gcgtacagtt tattgatgag ccggtaaaag
    60061 cgaccaccga gccagacggc agccgttata ttgaagtcca taacccgctg tctaccaccg
    60121 aagcccagtt tgaaggtcag gaaattgtgc caattaccct gacgaagagc gtgcagacag
    60181 tgaccggtca gccagatgtt gaccaggttg ttcttgatga agcgattaaa aaccgctccg
    60241 ggatgccggt tcgtctgaat taatcttcaa aacttaaagc aaaaggcgga ctcataatcc
    60301 gcctttttta tttgccagac cctagttggc cgggagtata actaacaaaa catatcccac
    60361 caacgccgcc cacaacagca tcggtattga atagagatgg aaacgccacc agatgcggcg
    60421 atcgttcgcc atacgtagcg caatcaaatt tgccagcgat ccgggtaata acccaaagcc
    60481 acctacgttt accgcccata ccagtaataa agacggcggc acatagttca gcaacaatat
    60541 ggtactcggc acgttactga tcacctgcga taaaccgatt gccgttaacc ataacccggg
    60601 ttcagataga tgactcacgt tacccaacac gccttgcaac gctggaagct gggtcagtaa
    60661 atggacgtcg ataaacatcg ccataaacac cagcagcagc gtccagtcca cactgagcac
    60721 cacgcgacgt gccagcagcg caaagcctgc cgccacaatc accagtcccc acagctcttg
    60781 tttgaactcc agcgccgtca gaaagacgat atacagcccc agacaactcc acaccagccg
    60841 cggtttccac tccggtgttt gcacccccgt atggtattgc atcgcctttc cagggaaaca
    60901 acaccagcac aggagcagga gcgtcagcat cattgcgcca gccagcggtg ccatttgggc
    60961 aataaatccg gcaaacgaaa gaccagaacg tccccagata agaatatttt gcgggttgcc
    61021 aattggcgtc agtagcgaac cagcgttgac tgccagcgcc tcaaaaataa tcagccgatt
    61081 aaccgggatc tcacacagtc tttttagcgt gatagtcagc ggaacaacaa taaacagcgc
    61141 gacatcgttg gtcagaaagg tagaaagcag cgccgccgcc agcaccataa acatcgccag
    61201 ccgacgctcc gtagcaaagc ggcgcaccat tttgcgcccc agcacatcaa aataaccgct
    61261 taactccaca cctttggtca gcagcatcag gccgcttaag gtgatgatgg tgtgccagtc
    61321 gatagcagca ggccaggatt tcggtgcaaa gggcacgaaa aagcttaatc cgataccaac
    61381 aagaattaat aactgaaaaa aacgatcgcc ttgcagcgtg cgtaaaaaag gcaggctcat
    61441 ttggcaccgt gtttctgggt aaacaaacga aaagcgtcga gcgtctcttc actaacatgg
    61501 tgctccatgc cttccgcgtc gcgacgggcg atttccggac tgacgcccaa caccaacaag
    61561 aaattttcga ctatctgatg tcgctcgcgg ctttcctgcg ccagcttctc tccttctgcc
    61621 gttaaaaaca cgccacgcca ggggatcatt tcaatcagcc ccatggttgc cagccgctta
    61681 agcattttag ccaccgtcgg ttgcgaaact cccagacgag cagccatgtc cacctgacga
    61741 gcttccccca cttccctgat caagtcagaa atcagctcaa cgtaatcatc aataagctcg
    61801 cgccgatgcg cctctctgac ctggcggaac ccttcaacgt gctcttccac gttcactaac
    61861 tgcgtcactt tttttgctgt tggcgtacct gcgcgacgac tcattgtgct tcctcattat
    61921 ggtgacgcat acatagcgtt ctcatttcgt gcgcacattg taaaccagag ttgcgaaggt
    61981 acaaaaaatt aacgttttag caatagctat ataatatagc ctgtgctata tctgtatgta
    62041 atgcaatcat ccctcaagga tcgacgggat tagcaagtca ggaggtctta tgaatgagtt
    62101 caagaggtgt atgcgcgtgt ttagtcattc tccctttaaa gtacggttaa tgctgctctc
    62161 tatgttgtgc gatatggtca acaacaaacc gcagcaagat aaaccttccg ataaatagcg
    62221 gcgtcgcggt acgccgcttc actcctgctt tcatgcaggc ataacgcgtt ttggtctgaa
    62281 aaaccccact ttttgtcgga tttgcaatcc ccttcgcaaa agatttgttc gtcagtagtt
    62341 gacctgaacg gcggctcgct ctatcttctt gcagccctgc gtatattgcg gctcgcggat
    62401 gcggacccct ttccactctt cacgcactct tgcaggtatt gacccttgac gccagggtaa
    62461 gcacatggcg tttgttacga tagtggcata tgaatttaac cctcaaagaa tcgcttgtta
    62521 cccgtagccg ggtatttagc ccgtggactg cgttctactt tttacagtcg ctattaatta
    62581 acctcggctt aggttacccc ttcagtttgc tctacaccgc tgcgtttacg gctattttgc
    62641 ttttgctatg gcgaacattg cctcgcgtac aaaaagttct ggtcggtgtc agttcgctgg
    62701 tggcggcttg ttatttccct tttgctcagg cctacggcgc gcctaatttc aatacattgc
    62761 tggcattgca ctccaccaat atggaagagt cgaccgaaat cctgacgatt tttccgtggt
    62821 acagctacct ggtcggctta tttatttttg cgctcggcgt aatagcaatc aggcgaaaaa
    62881 aagagaatga aaaagcgcgc tggaatacct tcgacagcct gtgtctggta ttcagtgtgg
    62941 cgacattttt tgttgctccc gtgcaaaacc tggcctgggg tggcgtattt aaactgaaag
    63001 atactggcta tccggtattt cgttttgcta aggatgtcat cgtcaataat aacgaggtga
    63061 ttgaagagca agaacggatg gcaaaacttt ccggaatgaa agatacctgg acggtcactg
    63121 ccgttaagcc gaagtatcag acctatgtgg tggtgatcgg tgaaagcgcg cgtcgcgatg
    63181 ccctcggtgc ctttggcggt cactgggaca ataccccgtt tgccagcagc gttaacggtt
    63241 tgatatttgc tgactacatt gccgccagtg gctccacgca gaaatcgctt ggcttaacgc
    63301 tcaatcgcgt tgtcgatggc aaaccacagt ttcaggataa ctttgtcacc ctggcaaatc
    63361 gcgcgggctt ccagacctgg tggttttcca accagggtca aatcggcgaa tacgataccg
    63421 ctatcgccag catcgccaaa cgagcagatg aagtgtactt cctgaaagaa ggtaattttg
    63481 aagcagataa aaacaccaaa gacgaagcgt tactggatat gaccgctcaa gtgctggcgc
    63541 aagagcactc gcaaccgcag ctgattgttc tacatctgat gggctcacat ccgcaggcct
    63601 gcgacaggac acaaggaaaa tacgaaacct ttgtgcaatc gaaagaaacg tcgtgctatc
    63661 tctataccat gacgcaaacg gacgatttac tgcgcaagct gtacgatcag ttacgcaaca
    63721 gcggcagcag cttctcgctg gtttactttt ctgaccacgg tctggccttt aaagagcgcg
    63781 gtaaagacgt gcaatacctt gcccatgatg ataaatatca gcaaaatttc caggtgcctt
    63841 ttatggtcat ttccagcgac gataaagcgc atcgtgtgat taaagcccgc cgctcagcca
    63901 atgacttctt aggctttttc tcccagtgga cggggattaa agcgaaggaa attaacatca
    63961 aatacccgtt tatatctgag aagaaagccg ggccgatata catcaccaac ttccagttac
    64021 agaaggtgga ttacaaccat ctcggaaccg atattttcga cccgaaacct taaaaacaaa
    64081 aatccgcccc gagaggcgga ttttttatat caccaaagtg attagaagcg gtaaccaaca
    64141 ccggcaatcc aggtgcctac gtcaacgcta cgaatacggc tctgctcgta agagaagtcc
    64201 agagcaacgt tttccatcgg gttgaactgc agacccgcac cgtaggagaa accgtagtcg
    64261 ctggtgtcgt gtttgtaggt cgggtattca gtggtctgga atttaccata acccacaccc
    64321 actacaccgt agatgcttgc ccagtcgtta atgcggtaag ccggaccagc agtgatgccg
    64381 tagtactggt ttttgttgta gtcaccagag cttgcagtac ggcttttctc ggtgtaagtg
    64441 aaagaaccga tcacacccag cgggctgttg tcttcttcat agcggtattt caggttgaaa
    64501 ccgcccattt tgttcatttg gccctgagcg tcgctctgtg cgtaaccgcc agttacagta
    64561 gaagtcgcag ctacggaagt acctgcggtg aaagccagaa ctgcggccag tgctgaaaga
    64621 catgcaattt ttttcataac cacctcaaat gtgattcaaa taagtcctaa gttttaaata
    64681 tatcaaaaat taatgggaaa ctcttcgcga tttgtgatgt ctaacgggcc atttcatgta
    64741 acagaacgtt tccatacacc gctatccatc taaatttaaa tcactttttc agagaactgc
    64801 gtaagtatta cgcatgtttt ccctgtcatt catccagatt attcctaatc accagactaa
    64861 tgattccatc aatcctggcg cattttagtc aaaacggggg aaaatttttt caacaaatgc
    64921 tcaaccagca ttgggtatat ccagtacact ccacgcttta cttaagtcta gatatttgtg
    64981 ggagaaagga tgcctggttc attacgtaaa atgccggtct ggttaccaat agtcatattg
    65041 ctcgttgcca tggcgtctat tcagggtgga gcctcgttag ctaagtcact ttttcctctg
    65101 gtgggcgcac cgggtgtcac tgcgctgcgt ctggcattag gaacgctgat cctcatcgcg
    65161 ttctttaagc catggcgact gcgctttgcc aaagagcaac ggttaccgct gttgttttac
    65221 ggcgtttcgc tgggtgggat gaattatctt ttttatcttt ctattcagac agtaccgctg
    65281 ggtattgcgg tggcgctgga gttcaccgga ccactggcgg tggcgctgtt ctcttctcgt
    65341 cgcccggtag atttcgtctg ggttgtgctg gcggttcttg gtctgtggtt cctgctaccg
    65401 ctggggcaag acgtttccca tgtcgattta accggctgtg cgctggcact gggggccggg
    65461 gcttgttggg ctatttacat tttaagtggg caacgcgcag gagcggaaca tggccctgcg
    65521 acggtggcaa ttggttcgtt gattgcagcg ttaattttcg tgccaattgg agcgcttcag
    65581 gctggtgaag cactctggca ctggtcggtt attccattgg gtctggctgt cgctattctc
    65641 tcgaccgctc tgccttattc gctggaaatg attgccctca cccgtttgcc aacacggaca
    65701 tttggtacgc tgatgagcat ggaaccggcg ctggctgccg tttccgggat gattttcctc
    65761 ggagaaacac tgacacccat acagctactg gcgctcggcg ctatcatcgc cgcttcaatg
    65821 gggtctacgc tgacagtacg caaagagagc aaaataaaag aattagacat taattaaatt
    65881 tacatttctg catg
//
LOCUS       DAPOAV010000014        65537 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.014, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000014 DAPOAV010000000
VERSION     DAPOAV010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 65537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65537
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.014"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(71..436)
                     /locus_tag="RN951_001098"
     CDS             complement(71..436)
                     /locus_tag="RN951_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HDX2526131.1"
                     /translation="MDWYLKVLKNYVGFRGRARRKEYWMFILVNIIFTFVLGLLDKML
                     GWQRAGGEGILTTIYGILVFLPWWAVQFRRLHDTDRSAWWALLFLIPFIGWLIIIVFN
                     CQAGTPGENRFGPDPKLEP"
     gene            complement(730..1716)
                     /gene="yqjG"
                     /locus_tag="RN951_001099"
     CDS             complement(730..1716)
                     /gene="yqjG"
                     /locus_tag="RN951_001099"
                     /EC_number="1.8.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionyl-hydroquinone reductase YqjG"
                     /protein_id="HDX2526132.1"
                     /translation="MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTG
                     TGGFIAEKDRYHLYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSF
                     PGATGDTLYQNEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAF
                     DALGAKAGDYYPPALQTKIDELNGWIYDTVNNGVYKAGFATSQEAYDEAVAKVFESLA
                     RLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRD
                     IYQMPGIAETVNFDHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDVRFG"
     gene            complement(1786..2178)
                     /locus_tag="RN951_001100"
     CDS             complement(1786..2178)
                     /locus_tag="RN951_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008503138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HDX2526133.1"
                     /translation="MKKLEDVGVLVARILMPILFITAGWGKITGYAGTQQYMEAMGVP
                     GFMLPLVILLEFGGGLAILFGFLTRTTALFTAGFTLLTAFLFHSNFAEGVNSLMFMKN
                     LTISGGFLLLAITGPGAYSIDRLLNKKW"
     gene            complement(2364..2663)
                     /locus_tag="RN951_001101"
     CDS             complement(2364..2663)
                     /locus_tag="RN951_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqjK-like family protein"
                     /protein_id="HDX2526134.1"
                     /translation="MSSKVERERRKAQLLSQIQQQRLDLSASRREWLETTGAYDRRWN
                     MLLSLRSWALVGSSVMAIWTIRHPNMLVRWARRGFGVWSAWRLVKTTLKQQQLRG"
     gene            complement(2653..3057)
                     /locus_tag="RN951_001102"
     CDS             complement(2653..3057)
                     /locus_tag="RN951_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDX2526135.1"
                     /translation="MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEK
                     ANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIW
                     TLRKSRKSTLLRHTRHELANDRQLLEEESREQ"
     gene            complement(3060..3365)
                     /locus_tag="RN951_001103"
     CDS             complement(3060..3365)
                     /locus_tag="RN951_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 domain-containing protein"
                     /protein_id="HDX2526136.1"
                     /translation="MSKEHTTEHLRAELKSLSDTLEEVLSSSGEKSKEELSKIRSKAE
                     QALKQSRYRLGETGDAIAKQTRVAAARADEYVRENPWTGVGIGAAIGVVLGVLLSRR"
     gene            complement(3403..3771)
                     /locus_tag="RN951_001104"
     CDS             complement(3403..3771)
                     /locus_tag="RN951_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1090 domain-containing protein"
                     /protein_id="HDX2526137.1"
                     /translation="MKYRIALAVSLFALSAGSYATTLCQEKEQNILKEISYAEKHQNQ
                     NRIDGLNKALSEVRANCSDSQLRADHQKKIAKQKDEVAERQQDLAEAKQKGDADKIAK
                     RERKLAEAQEELKKLEARDY"
     gene            complement(3918..4301)
                     /gene="mzrA"
                     /locus_tag="RN951_001105"
     CDS             complement(3918..4301)
                     /gene="mzrA"
                     /locus_tag="RN951_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EnvZ/OmpR regulon moderator MzrA"
                     /protein_id="HDX2526138.1"
                     /translation="MQIPRMSLRQLAWSGAVLLLVGTLLLAWSAVRQQESTLAIRAVH
                     QGTTMPDGFSIWHHLDAHGIPFKSITPKNDTLLITFDSSDQSAAAKAVLDRTLPHGYI
                     IAQQDNNSQAMQWLTRLRDNSHRFG"
     gene            complement(4305..4967)
                     /locus_tag="RN951_001106"
     CDS             complement(4305..4967)
                     /locus_tag="RN951_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDX2526139.1"
                     /translation="MELLTQLLQALWAQDFETLANPSMIGMLYFVLFVILFLENGLLP
                     AAFLPGDSLLVLVGVLIAKGAMGYPQTILLLTVAASLGCWVSYIQGRWLGNTRTVQNW
                     LSHLPAHYHQRAHHLFHKHGLSALLIGRFIAFVRTLLPTIAGLSGLNNARFQFFNWMS
                     GLLWVLILTTLGYMLGKTPVFLKYEDQLMSCLMLLPVVLLVFGLAGSLVVLWKKKYGN
                     RG"
     gene            complement(5312..6088)
                     /gene="exuR"
                     /locus_tag="RN951_001107"
     CDS             complement(5312..6088)
                     /gene="exuR"
                     /locus_tag="RN951_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ExuR"
                     /protein_id="HDX2526140.1"
                     /translation="MEITEPRRLYQQLAADLKERIEQGVYLVGDKLPAERFIADEKNV
                     SRTVVREAIIMLEVEGYVEVRKGSGIHVVSNQPRHQQAADNNMEFANYGPFELLQARQ
                     LIESNIAEFAATQVTKQDIMKLMAIQEQARGEQCFRDSEWDLQFHIQVALATQNSALA
                     AIVEKMWTQRSHNPYWKKLHEHIDSRTVDNWCDDHDQILKALIRKDPHAAKLAMWQHL
                     ENTKIMLFNETSDDFEFNADRYLFAENPVVHLDTATSGSK"
     gene            complement(6218..7516)
                     /gene="exuT"
                     /locus_tag="RN951_001108"
     CDS             complement(6218..7516)
                     /gene="exuT"
                     /locus_tag="RN951_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708898.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexuronate transporter ExuT"
                     /protein_id="HDX2526141.1"
                     /translation="MRKIKGLRWYMIALVTLGTVLGYLTRNTVAAAAPTLMEELNIST
                     QQYSYIIAAYSAAYTVMQPVAGYVLDVLGTKIGYAMFAVLWAVFCGATALAGSWGGLA
                     VARGAVGAAEAAMIPAGLKASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVM
                     HSWQMAFIISGALSFIWAMAWLIFYKHPRDQKHLTDEERDYIINGQEAQHQVSTAKKM
                     SVGQILRNRQFWGIALPRFLAEPAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFA
                     DLGCILGGYLPPLFQRWFGVNLIVSRKMVVTLGAVLMIGPGMIGLFTNPYVAIMLLCI
                     GGFAHQALSGALITLSSDVFGRNEVATANGLTGMSAWLASTLFALVVGALADTIGFSP
                     LFAVLAVFDLLGALVIWTVLQNKPAIEVAQETHNDPAPQH"
     gene            7999..9411
                     /gene="uxaC"
                     /locus_tag="RN951_001109"
     CDS             7999..9411
                     /gene="uxaC"
                     /locus_tag="RN951_001109"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HDX2526142.1"
                     /translation="MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAED
                     YRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYH
                     WTHLELRRPFGITGKLLSPSTADKIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDP
                     IDSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADL
                     QTALTKRLDHFAAHGCKVSDHALDVVMFAEANEAELDSILARRLAGETLSEHEVAQFK
                     TAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLL
                     SKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMER
                     QMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLG
                     EMVKNICFNNARDYFAIELN"
     gene            9426..10913
                     /gene="uxaA"
                     /locus_tag="RN951_001110"
     CDS             9426..10913
                     /gene="uxaA"
                     /locus_tag="RN951_001110"
                     /EC_number="4.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HDX2526143.1"
                     /translation="MQYIKIHALDNVAVALADLAEGTEVSVDNQTVTLRQDVARGHKF
                     ALTDIAKGANVIKYGLPIGYALADIAAGVHVHAHNTRTNLSDLDQYRYQPDFQDLPAQ
                     AADREVQIYRRANGDVGVRNELWILPTVGCVNGIARQIQNRFLKETNNAEGTDGVFLF
                     SHTYGCSQLGDDHINTRTMLQNMVRHPNAGAVLVIGLGCENNQVAAFRETLGDIDPER
                     VHFMICQQQDDEIEAGIEHLHQLYNVMRNDKREPGKLSELKFGLECGGSDGLSGITAN
                     PMLGRFSDYVIANGGTTVLTEVPEMFGAEQLLMDHCRDEATFEKLVTMVNDFKQYFIA
                     HDQPIYENPSPGNKAGGITTLEDKSLGCTQKAGSSVVVDVLRYGERLKTPGLNLLSAP
                     GNDAVATSALAGAGCHMVLFSTGRGTPYGGFVPTVKIATNSELAAKKKHWIDFDAGQL
                     IHGKAMPQLLEEFIDTIVEFANGKQTCNERNDFRELAIFKSGVTL"
     gene            10996..11547
                     /locus_tag="RN951_001111"
     CDS             10996..11547
                     /locus_tag="RN951_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgjV family protein"
                     /protein_id="HDX2526144.1"
                     /translation="MTAYWLAQGVGVIAFLIGITTFFNRDERRFKKQLSVYSAVIGVH
                     FFLLGTYPAGASAILNAIRTLITLRTRSLWVMAIFIVLTGGIGLAKFHHPVELLPVIG
                     TIVSTWALFRCKGLTMRCVMWFSTCCWVIHNFWAGSIGGTMIEGSFLLMNGLNIIRFW
                     RMQKRGIDPFKVEKTPSAVDERG"
     gene            complement(11552..12796)
                     /gene="sstT"
                     /locus_tag="RN951_001112"
     CDS             complement(11552..12796)
                     /gene="sstT"
                     /locus_tag="RN951_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HDX2526145.1"
                     /translation="MTTQRSPGLFRRLAHGSLVKQILVGLVLGILLAWISKPAAEAVG
                     LLGTLFVGALKAVAPILVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVF
                     SFAFPSTLHLSSSAGDISPPSGIVEVMRGLVMSMVSNPIDALLKGNYIGILVWAIGLG
                     FALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAQL
                     LVVLVGCMLLVALVVNPLLVWWKIRRNPFPLVLLCLRESGVYAFFTRSSAANIPVNMA
                     LCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVNTLGIPVDLPTALLLSVVA
                     SLCACGASGVAGGSLLLIPLACNMFGISNDIAMQVVAVGFIIGVLQDSCETALNSSTD
                     VLFTAAACQAEDDRLANSALRN"
     gene            complement(13195..14160)
                     /gene="alx"
                     /locus_tag="RN951_001113"
     CDS             complement(13195..14160)
                     /gene="alx"
                     /locus_tag="RN951_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family membrane protein Alx"
                     /protein_id="HDX2526146.1"
                     /translation="MNTVGTPLLWGGFAVVVAIMLAIDLLLQGRRGAHAMTMKQAAAW
                     SLVWVTLSLLFNAAFWWYLVQTEGRAVADPQALAFLTGYLIEKSLAVDNVFVWLMLFS
                     YFSVPAALQRRVLVYGVLGAIVLRTIMIFTGSWLISQFDWILYIFGAFLLFTGVKMAL
                     AHEDESGIGDKPLVRWLRGHLRMTDTIDNEHFFVRKNGLLYATPLMLVLILVELSDVI
                     FAVDSIPAIFAVTTDPFIVLTSNLFAILGLRAMYFLLAGVAERFSMLKYGLAVILVFI
                     GIKMLIVDFYHIPIAVSLGVVFGILVMTFIINAWVNYRHDKQRGG"
     gene            complement(14443..15429)
                     /locus_tag="RN951_001114"
     CDS             complement(14443..15429)
                     /locus_tag="RN951_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417558.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDX2526147.1"
                     /translation="MIRFAVIGTNWITRQFVEAAHESGKYKLTAVYSRSLEQAQHFAN
                     DFSVEHLFTSLEAMAESDAIDAVYIASPNSLHFSQTQLFLSHKINVICEKPLASNLAE
                     VDAAIACARENQVVLFEAFKTACLPNFHLLRQALPKVGKLRKVFFNYCQYSSRYQRYL
                     DGENPNTFNPAFSNGSIMDIGFYCLASAVALFGEPKSVQATASLLASGVDAQGVVVMD
                     YGDFSVTLQHSKVSDSVLASEIQGEAGSLVIEKLSECQKVCFVPRGSQMQDLTQPQHI
                     NTMLYEAELFATLVDEHLVDHPGLAVSRITAKLLTEIRRQTGVIFPADSVKL"
     gene            complement(15508..16200)
                     /locus_tag="RN951_001115"
     CDS             complement(15508..16200)
                     /locus_tag="RN951_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin high temperature exclusion protein"
                     /protein_id="HDX2526148.1"
                     /translation="MLRAFARLLLRICFSRRTLKIACLLLLVAGATILIADRVMVNAS
                     KQLTWSDVNAVPARNVGLLLGARPGNRYFTRRIDTAAALYHAGKVKWLLVSGDNGRKN
                     YDEASGMQQALIAKGVPAKVIFCDYAGFSTLDSVVRAKKVFGENHITIISQEFHNQRA
                     IWLAKQYGIDAIGFNAPDLNMKHGFYTQLREKLARVSAVIDAKILHRQPKYLGPSVMI
                     GPFSEHGCPAQK"
     gene            complement(16277..16780)
                     /locus_tag="RN951_001116"
     CDS             complement(16277..16780)
                     /locus_tag="RN951_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311994.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HDX2526149.1"
                     /translation="MNNLTYLQGYPEQLLSQVRTLINEQRLGDVLAKRYPGTHDYATD
                     KALWQYTQDLKNQFLRNAPPINKVMYDNKIHVLKNALGLHSAVSRVQGGKLKAKAEIR
                     VATVFRNAPEPFLRMIVVHELAHLKEKEHNKAFYQLCCHMEPQYHQLEFDTRLWLTQL
                     SLGQDKI"
     gene            16865..18001
                     /gene="rlmG"
                     /locus_tag="RN951_001117"
     CDS             16865..18001
                     /gene="rlmG"
                     /locus_tag="RN951_001117"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417555.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(1835)-N(2))-methyltransferase
                     RlmG"
                     /protein_id="HDX2526150.1"
                     /translation="MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEI
                     RGPVLILNDAFGALSCALAEHKPYSIGDSYISELATRENLRLNGIDESSVKFLDSTAD
                     YPQQPGVVLIKVPKTLALLEQQLRALRKVVTSDTRIIAGAKARDIHTSTLELFEKVLG
                     PTTTTLAWKKARLINCTFNEPPLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGAR
                     FFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRMNVETNM
                     PEALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKING
                     ELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKTVKLGRRR"
     gene            18192..18275
                     /locus_tag="RN951_001118"
                     /pseudo
     CDS             18192..18275
                     /locus_tag="RN951_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311992.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HigB family
                     toxin"
     gene            18272..18688
                     /gene="higA"
                     /locus_tag="RN951_001119"
     CDS             18272..18688
                     /gene="higA"
                     /locus_tag="RN951_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HigA"
                     /protein_id="HDX2526151.1"
                     /translation="MIAIADILQAGEKLTAVAPFLAGIQNEEQYTQALELVDHLLLND
                     PENPLLDLVCAKITAWEESAPEFAEFNAMAQAMPGGIAVIRTLMDQYGLTLSDLPEIG
                     SKSMVSRVLSGKRKLTLEHAKKLATRFGISPALFID"
     gene            complement(18733..20751)
                     /gene="fadH"
                     /locus_tag="RN951_001120"
     CDS             complement(18733..20751)
                     /gene="fadH"
                     /locus_tag="RN951_001120"
                     /EC_number="1.3.1.34"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 2,4-dienoyl-CoA reductase"
                     /protein_id="HDX2526152.1"
                     /translation="MSYPSLFAPLDLGFTTLKNRVLMGSMHTGLEEYPDGAERLAAFY
                     AERARHGVALIVSGGIAPDLTGVGMEGGAMLNDASQIPHHRTITEAVHQEGGKIALQI
                     LHTGRYSYQPHLVAPSALQAPINRFVPHELTHEEILQLIDDFAHCAQLAREAGYDGVE
                     VMGSEGYLINEFLTLRTNQRSDQWGGDYRNRMRFAVEVVRTVRERVGNDFIIIYRLSM
                     LDLVEGGGTFAETVELAQAIEAAGATIINTGIGWHEARIPTIATPVPRGAFTWVTRKL
                     KGHVSLPLVTTNRINDPQVADDILSRGDADMVSMARPFLADAELLSKAQSGRADEINT
                     CIGCNQACLDQIFVGKVTSCLVNPRACHETKMPILPAVQKKNLAVVGAGPAGLAFAIN
                     AAARGHQVTLFDAHSEIGGQFNIAKQIPGKEEFYETLRYYHRMIEVTGVTLKLNHTVT
                     ADQLQAFDETILASGIVPRVPPIDGIDHPKVLSYLDVLRDKAPVGNKVAIIGCGGIGF
                     DTAMYLSQPGESTSQNIARFCNEWGIDSSLQQAGGLSPQGMQIPRSPRQIVMLQRKAS
                     KPGQGLGKTTGWIHRTTLLSRGVKMIPSVSYQKIDDDGLHVVINGETQVLAVDNVVIC
                     AGQEPNRALAQPLIDSGKTVHLIGGCDVAMELDARRAIAQGTRLALEI"
     gene            complement(21077..23428)
                     /gene="ygjK"
                     /locus_tag="RN951_001121"
     CDS             complement(21077..23428)
                     /gene="ygjK"
                     /locus_tag="RN951_001121"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDX2526153.1"
                     /translation="MKIKTILTPVTCALLISFSAHAANADNYKNVINRTGAPQYMKDY
                     DYDDHQRFNPFFDLGAWHGHLLPDGPNTMGGFPGVALLTEEYINFMASNFDRLTVWQD
                     GKKVDFTLEAYSIPGALVQKLTAKDVQVEMTLRFATPRTSLLETKITSNKPLDLVWDG
                     ELLEKLEAKEGKPLSDKTIAGEYPDYQRKISATRDGLKVTFGKVRATWDLLTSGESEY
                     QVHKSLPVQTEINGNRFTSKAHINGSTTLYTTYSHLLTAQEVSKEQMQIRDILARPAF
                     YLTASQQRWEEYLKKGLTNPDATPEQTRVAVKAIETLNGNWRSPGGAVKFNTVTPSVT
                     GRWFSGNQTWPWDTWKQAFAMAHFNPDIAKENIRAVFSWQIQPGDSVRPQDVGFVPDL
                     IAWNLSPERGGDGGNWNERNTKPSLAAWSVMEVYNVTQDKAWLAEMYPKLVAYHDWWL
                     RNRDHNGNGVPEYGATRDKAHNTESGEMLFTVKKGNKEETQSGLNNYARVVEKGQYDS
                     LEIPAQVAASWESGRDDAAVFGFIDKEQLDKYVANGGKRSDWTVKFAENRSQDGTLLG
                     YSLLQESVDQASYMYSDNHYLAEMATILGKPEEAKRYRQLAQQLADYINTCMFDPTTQ
                     FYYDVRIEDKPLANGCAGKPIVERGKGPEGWSPLFNGAATQANADAVVKVMLDPKEFN
                     TFVPLGTAALTNPAFGADIYWRGRVWVDQFWFGLKGMERYGYRDDALKLADTFFRHAK
                     GLTADGPIQENYNPLTGAQQGAPNFSWSAAHLYMLYNDFFRKQ"
     gene            complement(23445..24515)
                     /gene="ygjJ"
                     /locus_tag="RN951_001122"
     CDS             complement(23445..24515)
                     /gene="ygjJ"
                     /locus_tag="RN951_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YgjJ"
                     /protein_id="HDX2526154.1"
                     /translation="MKLITAPCRALLALPFCYAFSAAGEEARPAEHDDTKTPAITSTS
                     SPSFRFYGELGVGGYMDLEGENKHKYSDGTYIEGGLEMKYGSWFGLIYGEGWTVQADH
                     DGNAWVPDHSWGGFEGGINRFYGGYRTNDGTEIMLSLRQDSSLDDLQWWGDFTPDLGY
                     VIPNTRDIMTALKVQNLSGNFRYSVTATPAGHHDESKAWLHFGKYDRYDDKYTYPAMM
                     NGYIQYDLAEGITWMNSLEITDGTGQLYLTGLLTPNFAARAWHHTGRADGLDVPGSES
                     GMMVSAMYEALKGVYLSTAYTYAKHRPDHADDETTSFMQFGIWYEYGGGRFATAFDSR
                     FYMKNASHNPSDQIFLMQYFYW"
     gene            complement(24649..26082)
                     /locus_tag="RN951_001123"
     CDS             complement(24649..26082)
                     /locus_tag="RN951_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDX2526155.1"
                     /translation="MSDTKRNTIGKFGLLSLTFAAVYSFNNVINNNIELGLASAPMFF
                     LATIFYFIPFCLIIAEFVSLNKNSEAGVYAWVKSSLGGRWAFITAYTYWFVNLFFFTS
                     LLPRVIAYASYAFLGYEYIMTPVATTIISMVLFAFSTWVSTNGAKMLGPITSVTSTLM
                     LLLTLSYILLAGTALVGGVQPADPITVDAMIPNFNWAFLGVTTWIFMAAGGAESVAVY
                     VNDVKGGSKSFVKVIILAGIFIGVLYSVSSVLINVFVSSKELKFTGGSVQVFHGMAAY
                     FGLPEALMNRFVGLVSFTAMFGSLLMWTATPVKIFFSEIPEGIFGKKTVELNENGVPA
                     RAAWIQFLIVIPLMIIPMLGSNTVQDLMNTIINMTAAASMLPPLFIMLAYLNLRAKLD
                     HLPRDFRMGSRRTGIIVVSMLIAIFAVGFVASTFPTGANILTIIFYNVGGIVIFLGFA
                     WWKYSKYIKGLTAEERHIEATPASNVD"
     gene            complement(26145..26594)
                     /locus_tag="RN951_001124"
     CDS             complement(26145..26594)
                     /locus_tag="RN951_001124"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase subunit beta"
                     /protein_id="HDX2526156.1"
                     /translation="MRIIDNLEQFRQIYASGKKWQRCVEAIENIDNIQPGVAHSIGDS
                     LTYRVETDSATDALFTGHRRYFEVHYYLQGQQKIEYAPKETLQVVEYYRDETDREYLK
                     GCGETVEVHEGQIVICDIHEAYRFICNNAVKKVVLKVTIEDGYFHNK"
     gene            complement(26591..29683)
                     /gene="ebgA"
                     /locus_tag="RN951_001125"
     CDS             complement(26591..29683)
                     /gene="ebgA"
                     /locus_tag="RN951_001125"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311985.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase subunit alpha"
                     /protein_id="HDX2526157.1"
                     /translation="MNRWENIQLTHENRLAPRAYFFSYDSVAQARTFARETSSLFLPL
                     SGQWNFHFFDHPLQVPEAFTSELMADWGHITVPAMWQMEGHGKLQYTDEGFPFPIDVP
                     FVPSDNPTGAYQRIFTLSDGWQGKQTLIKFDGVETYFEVYVNGQYVGFSKGSRLTAEF
                     DISAMVKTGDNLLCVRVMQWADSTYVEDQDMWWSAGIFRDVYLVGKHLTHINDFTVRT
                     DFDEAYCDATLSCEVVLENLAASPVVTTLEYTLFDGERVVHSSAIDHLAIEKLTSASF
                     AFTVEQPQQWSAESPYLYHLVMTLKDANGNVLEVVPQRVGFRDIKVRDGLFWINNRYV
                     MLHGVNRHDNDHRKGRAVGMDRVEKDLQLMKQHNINSVRTAHYPNDPRFYELCDIYGL
                     FVMAETDVESHGFANVGDISRITDDPQWEKVYVERIVRHIHAQKNHPSIIIWSLGNES
                     GYGCNIRAMYHAAKALDDTRLVHYEEDRDAEVVDIISTMYTRVPLMNEFGEYPHPKPR
                     IICEYAHAMGNGPGGLTEYQNVFYKHDCIQGHYVWEWCDHGIQAQDDNGNVWYKFGGD
                     YGDYPNNYNFCLDGLIYSDQTPGPGLKEYKQVIAPVKIHALDLTRGELKVENKLWFTT
                     LDDYTLHAEVRVEGETLATQQIKLRDVAPNSEAPLQITLPQLDAREAFLNITVTKDSR
                     TRYSEAGHSIATYQFPLKENTAQPVPFAPNNARPLTLEDDRLSCTVRGYNFAITFSKM
                     SGKPTSWQVNGESLLTREPKINFFKPMIDNHKQEYEGLWQPNHLQIMQEHLRDFAVEQ
                     SDGEVLIISRTVIAPPVFDFGMRCTYIWRIAADGQVNVALSGERYGDYPHIIPCIGFT
                     MGINGEYDQVAYYGRGPGENYADSQQANIIDIWRSTVDAMFENYPFPQNNGNRQHVRW
                     TALTNRHGNGLLVVPQRPINFSAWHYTQENIHAAQHCNELQRSDDITLNLDHQLLGLG
                     SNSWGSEVLDSWRVWFRDFSYGFTLLPVSGGEATAQSLASYEFGAGFFSTNLHSENKQ
                     "
     gene            complement(29867..30850)
                     /gene="ebgR"
                     /locus_tag="RN951_001126"
     CDS             complement(29867..30850)
                     /gene="ebgR"
                     /locus_tag="RN951_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator EbgR"
                     /protein_id="HDX2526158.1"
                     /translation="MATLKDIAIEAGVSLATVSRVLNDDPTLNVKEETKHRILEIAEK
                     LEYKTSSARKLQTGAVNQHHILAIYSYQQELEINDPYYLAIRHGIETQCEKLGIELTN
                     CYEHSGLPDIKNVTGILIVGKPTPALRAAACALTDNICFIDFHEPGSGYDAVDIDLAR
                     ISKEIIDFYINQGVNRIGFIGGEDEPGKADIREVAFAEYGRLKQVVREEDIWRGGFSS
                     SSGYELAKQMLAREDYPKALFVASDSIAIGVLRAIHERGLNIPQDISLISVNDIPTAR
                     FTFPPLSTVRIHSEMMGSQGVNLVYEKARDGRALPLLVFVPSKLKLRGTTR"
     gene            31069..31401
                     /locus_tag="RN951_001127"
     CDS             31069..31401
                     /locus_tag="RN951_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HDX2526159.1"
                     /translation="METVAYADFARLEMRVGKIVEVKRHENADKLYIVQVDVGEKTLQ
                     TVTSLVPYYSEEELMGKTVVVLCNLQKAKMRGETSECMLLCAETDDGSESVLLTPERM
                     MPAGVRVV"
     gene            complement(31443..32822)
                     /gene="ygjG"
                     /locus_tag="RN951_001128"
     CDS             complement(31443..32822)
                     /gene="ygjG"
                     /locus_tag="RN951_001128"
                     /EC_number="2.6.1.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417544.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine aminotransferase"
                     /protein_id="HDX2526160.1"
                     /translation="MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKE
                     HVNPGFLEYRKSVTAGGDYGAVEWQAGGLNTLVDTQGQEFIDCLGGFGIFNVGHRNPV
                     VVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKL
                     AKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAM
                     RTALNECKKTGDDVAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTG
                     MGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFG
                     GNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMA
                     IEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALA
                     AMRVSVEEA"
     gene            33240..34760
                     /gene="aer"
                     /locus_tag="RN951_001129"
     CDS             33240..34760
                     /gene="aer"
                     /locus_tag="RN951_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311981.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerotaxis sensor receptor Aer"
                     /protein_id="HDX2526161.1"
                     /translation="MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGFT
                     LQELQGQPHNMVRHPDMPKAAFADMWFTLKKGEPWSGIVKNRRKNGDHYWVRANAVPM
                     VREGKISGYMSIRTRATDEEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLP
                     LRWRARGVMTLMFILLAAMLWFVAAPVVTYFLCVLVVLLASACFEWQIVRPIENVARQ
                     ALKVATGERNSVEHLNRSDELGLTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAK
                     GTDELNEHTQQTVDNVQQTVATMNQMAASVKQNSATASAADKLSITASNAAVQGGEAM
                     TTVIKTMDDIADSTQRIGTITSLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGE
                     VRHLASRSANAANDIRKLIDASADKVQSGSQQVHAAGRTMEDIVAQVKNVTQLIAQIS
                     HSTLEQADGLSSLTRAVDELNLITQKNAELVEESAQVSAMVKHRASRLEDAVTVLH"
     gene            complement(34914..35537)
                     /gene="nfeR"
                     /locus_tag="RN951_001130"
                     /gene_synonym="yqjI"
     CDS             complement(34914..35537)
                     /gene="nfeR"
                     /locus_tag="RN951_001130"
                     /gene_synonym="yqjI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NfeR"
                     /protein_id="HDX2526162.1"
                     /translation="MSHHHEGCCKHEGQPRHEGCCKGEKSEHEHCGHGHQHEHGQCCG
                     GRHGRGGGRRQRFFGHGELRLVILDILSRDDSHGYELIKAIENLTQGNYTPSPGVIYP
                     TLDFLQEQSLITIREEEGGKKQIALTEQGAQWLEENREQVEMIEERIKARCVGAALRQ
                     NPQMKRALDNFKAVLDLRVNQSDISDAQIKKIIAVIDRAAFDITQLD"
     gene            35814..36578
                     /gene="nfeF"
                     /locus_tag="RN951_001131"
     CDS             35814..36578
                     /gene="nfeF"
                     /locus_tag="RN951_001131"
                     /EC_number="1.16.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent ferric chelate reductase"
                     /protein_id="HDX2526163.1"
                     /translation="MNNSPRYPQRVRNDLRFRELTVLRVERISAGFQRIVLGGEALDG
                     FTSRGFDDHSKLFFPQPDAHFVPPTVTEEGIVWPEGPRPPSRDYTPLYDELRHELAID
                     FFIHDGGVASGWAMQAQPGDKLTVAGPRGSLVVPEDYAYQLYVCDESGMPALRRRLET
                     LSKLAVKPQVSALVSVRDNACQDYLAHLDGFNIEWLAHDEQAVDARLAQMQIPADDYF
                     IWITGEGKVVKNLSRRFEAEQYDPQRVRAAAYWHAK"
     gene            complement(36632..36707)
                     /locus_tag="RN951_001132"
     tRNA            complement(36632..36707)
                     /locus_tag="RN951_001132"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(36672..36674),aa:Ile,seq:cat)
     gene            36832..37338
                     /gene="mug"
                     /locus_tag="RN951_001133"
     CDS             36832..37338
                     /gene="mug"
                     /locus_tag="RN951_001133"
                     /EC_number="3.2.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G/U mismatch-specific DNA glycosylase"
                     /protein_id="HDX2526164.1"
                     /translation="MVEDILAPGLRVVFCGINPGLSSAGTGFPFAHPANRFWKVIYQA
                     GFTDRQLKPQEAQHLLDYRCGVTKLVDRPTVQANEVSKQELHAGGRKLIEKIEDYQPQ
                     ALAILGKQAYEQGFSQRGAQWGKQTLTIGSTQIWVLPNPSGLSRVSLEKLVEAYRELD
                     QALVVRGR"
     gene            complement(37417..39258)
                     /gene="rpoD"
                     /locus_tag="RN951_001134"
     CDS             complement(37417..39258)
                     /gene="rpoD"
                     /locus_tag="RN951_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HDX2526165.1"
                     /translation="MEQNPQSQLKLLVTRGKEQGYLTYAEVNDHLPEDIVDSDQIEDI
                     IQMINDMGIQVMEEAPDADDLMLAENTADEDAAEAAAQVLSSVESEIGRTTDPVRMYM
                     REMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARLSD
                     LITGFVDPNAEEDLAPTATHVGSELSQEDLDDDEDEDEEDGDDDSADDDNSIDPELAR
                     EKFAELRAQYVVTRDTIKAKGRSHAAAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVM
                     MDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWFNAAIAMNKPWSEKLHDVS
                     EEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAK
                     KYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTI
                     RIPVHMIETINKLNRISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPISME
                     TPIGDDEDSHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREAKVLRMRFGID
                     MNTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLDD"
     gene            complement(39453..41198)
                     /gene="dnaG"
                     /locus_tag="RN951_001135"
     CDS             complement(39453..41198)
                     /gene="dnaG"
                     /locus_tag="RN951_001135"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDX2526166.1"
                     /translation="MAGRIPRVFINDLLARTDIVDLIDARVKLKKQGKNFHACCPFHN
                     EKTPSFTVNGEKQFYHCFGCGAHGNAIDFLMNYDKLEFVETVEELAAMHNLEVPFEAG
                     SGPSQIERHQRQTLYQLMDGLNTFYQQSLQQPVATSARQYLEKRGLSHEVIARFAIGF
                     APPGWDNVLKRFGGNPENRQSLIDAGMLVTNDQGRSYDRFRERVMFPIRDKRGRVIGF
                     GGRVLGNDTPKYLNSPETDIFHKGRQLYGLYEAQQDNAEPNRLLVVEGYMDVVALAQY
                     GINYAVASLGTSTTADHIQLLFRATNNVICCYDGDRAGRDAAWRALETALPYMTDGRQ
                     LRFMFLPDGEDPDTLVRKEGKEAFEARMEQAMPLSAFLFNSLMPQVDLSTPDGRARLS
                     TLALPLISQVPGETLRIYLRQELGNKLGILDDSQLERLMPKAAESGVSRPVPQLKRTT
                     MRILIGLLVQNPELATLVPPLENLDENKLPGLGLFRELVNTCLSQPGLTTGQLLEHYR
                     GTNNAATLEKLSMWDDIADKNIAEQTFTDSLNHMFDSLLELRQEELIARERTHGLSNE
                     ERLELWTLNQELAKK"
     gene            complement(41309..41524)
                     /gene="rpsU"
                     /locus_tag="RN951_001136"
     CDS             complement(41309..41524)
                     /gene="rpsU"
                     /locus_tag="RN951_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HDX2526167.1"
                     /translation="MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTE
                     RKRAKASAVKRHAKKLARENARRTRLY"
     gene            41762..42775
                     /gene="tsaD"
                     /locus_tag="RN951_001137"
     CDS             41762..42775
                     /gene="tsaD"
                     /locus_tag="RN951_001137"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001264383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HDX2526168.1"
                     /translation="MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVP
                     ELASRDHVRKTVPLIQAALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAW
                     NVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDD
                     AAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFA
                     ANTIRDNGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLR
                     AKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAEL
                     PAA"
     gene            complement(42818..44281)
                     /gene="ttdT"
                     /locus_tag="RN951_001138"
     CDS             complement(42818..44281)
                     /gene="ttdT"
                     /locus_tag="RN951_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-tartrate/succinate antiporter"
                     /protein_id="HDX2526169.1"
                     /translation="MKPSTEWWRYLAPLAVIAIIALIPVPAGLESHTWLYFAVFTGVI
                     VGLILEPVPGAVVAMVGISIIAILSPWLLFSPEQLAQPGFKFTAKSLSWAVSGFSNSV
                     IWLIFAAFMFGTGYEKTGLGRRIALILVKKMGHRTLFLGYAVMFSELILAPVTPSNSA
                     RGAGIIYPIIRNLPPLYQSQPNDSSSRSIGSYIMWMGIVADCVTSAIFLTAMAPNLLL
                     IGLMKSASHATLSWGDWFLGMLPLSILLVLLVPWLAYVLYPPVLKSGDQVPRWAETEL
                     QAMGPLCSREKRMLGLMVGALVLWIFGGDYIDAAMVGYSVVALMLLLRIISWDDIVSN
                     KAAWNVFFWLASLITLATGLNNTGFISWFGKLLAGSLSGYSPTMVMVALIVVFYLLRY
                     FFASATAYTSALAPMMIAAALAMPEIPLPVFCLMVGAAIGLGSILTPYATGPSPIYYG
                     SGYLPTADYWRLGAIFGLIFLVLLVITGLLWMPVVLL"
     gene            complement(44330..44935)
                     /gene="ttdB"
                     /locus_tag="RN951_001139"
     CDS             complement(44330..44935)
                     /gene="ttdB"
                     /locus_tag="RN951_001139"
                     /EC_number="4.2.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit beta"
                     /protein_id="HDX2526170.1"
                     /translation="MKKILTTPIKAEDLQDIRVGDVIYLTGTLVTCRDVCHRRLIELK
                     RPIPYDLNGKAIFHAGPIVRKNGDKWEMVSVGPTTSMRMESFEREFIEQTGVKLVVGK
                     GGMGPLTEEGCQKFKALHVIFPAGCAVLAATQVEEIEEVHWTELGMPESLWVCRVKEF
                     GPLIVSIDTHGNNLIAENKKLFAERRDPIVEEICEHVHYIK"
     gene            complement(44932..45843)
                     /gene="ttdA"
                     /locus_tag="RN951_001140"
     CDS             complement(44932..45843)
                     /gene="ttdA"
                     /locus_tag="RN951_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit alpha"
                     /protein_id="HDX2526171.1"
                     /translation="MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAE
                     TSSMGKIIYHTMFDNMQKAIDLNRPACQDTGEIMFFVKVGSRFPLLGELQSILKQAVE
                     EATVKAPLRHNAVEIFDEVNTGKNTGSGVPWVTWDIIPDNDDAEIEVYMAGGGCTLPG
                     RSKVLMPSEGYEGVVKFVFENISALAVNACPPVLVGVGIATSVETAAVLSRKAILRPI
                     GSRHPNPKAAELELRLEEGLNRLEIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTG
                     CWAHRRGTLLVHADLTFENLSHTRSAL"
     gene            46050..46982
                     /gene="ttdR"
                     /locus_tag="RN951_001141"
                     /gene_synonym="dan"
     CDS             46050..46982
                     /gene="ttdR"
                     /locus_tag="RN951_001141"
                     /gene_synonym="dan"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator TtdR"
                     /protein_id="HDX2526172.1"
                     /translation="MLNSWPLAKDLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQIL
                     ENTLATTLLNRSARGVALTESGQRCYEHALEILTQYQRLVDDVTQIKTRPEGMIRIGC
                     SFGFGRSHIAPAITELMRNYPELQVHFELFDRQIDLVQDNIDLDIRINDEIPDYYIAH
                     LLTKNKRILCAAPEYLQKYPQPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVK
                     VSGHLSSNSGEIVLQWALEGKGIMLRSEWDVLPFLESGKLVQVLPEYAQSANIWAVYR
                     EPLYRSMKLRVCVEFLAAWCQQRLGKPDEGYQVM"
     gene            complement(46995..47612)
                     /gene="plsY"
                     /locus_tag="RN951_001142"
     CDS             complement(46995..47612)
                     /gene="plsY"
                     /locus_tag="RN951_001142"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HDX2526173.1"
                     /translation="MSAIAPGMILIAYLCGSISSAILVCRLCGLPDPRTSGSGNPGAT
                     NVLRIGGKGAAVAVLIFDVLKGMLPVWGAYELGVSPFWLGLIAIAACLGHIWPVFFGF
                     KGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKP
                     QFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKFKRKREKDPE"
     gene            47717..48085
                     /gene="folB"
                     /locus_tag="RN951_001143"
     CDS             47717..48085
                     /gene="folB"
                     /locus_tag="RN951_001143"
                     /EC_number="4.1.2.25"
                     /EC_number="5.1.99.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708868.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional dihydroneopterin
                     aldolase/7,8-dihydroneopterin epimerase"
                     /protein_id="HDX2526174.1"
                     /translation="MDIVFIEQLSVITTIGVYDWEQTIEQKLVFDIEMAWDNRKAAKS
                     DDVADCLSYADIAETVVSHVEGARFALVERVAEEVAELLLARFNSPWVRIKLSKPGAV
                     ARAANVGVIIERGNNLKENN"
     gene            48175..48996
                     /gene="bacA"
                     /locus_tag="RN951_001144"
     CDS             48175..48996
                     /gene="bacA"
                     /locus_tag="RN951_001144"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDX2526175.1"
                     /translation="MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDT
                     AKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGESKGRLTLIHILLGMIPA
                     VVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMI
                     GCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGF
                     LTTGDIPMFAVGFITAFVVALIAIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF"
     gene            complement(49159..50397)
                     /gene="cca"
                     /locus_tag="RN951_001145"
     CDS             complement(49159..50397)
                     /gene="cca"
                     /locus_tag="RN951_001145"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused tRNA nucleotidyltransferase/2',3'-cyclic
                     phosphodiesterase/2' nucleotidase/phosphatase Cca"
                     /protein_id="HDX2526176.1"
                     /translation="MKIYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGYQQVGR
                     DFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEDDLKRRDLTINALAQDD
                     NGEIIDPYNGLGDLQNRLLRHVSPAFGEDPLRVLRVARFAARYAHLGFRIADETLTLM
                     REMTHAGELEHLTPERVWKETESALTTRNPQVFFQVLRDCGALRVLFPEIDALFGVPA
                     PARWHPEIDTGIHTLMTLSMAAMLSPQVDVRFATLCHDLGKGLTPPELWPRHHGHGPA
                     GVKLVEQLCQRLRVPNEIRDLARLVAEFHDLIHTFPMLNPKTIVKLFDSIDAWRKPQR
                     VEQLALTSEADVRGRTGFESADYPQGRWLREAWEVAQSVPTKAVVEAGFKGVEIREEL
                     TRRRIAAIASWKEQRCPKPD"
     gene            complement(50461..51081)
                     /locus_tag="RN951_001146"
     CDS             complement(50461..51081)
                     /locus_tag="RN951_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDX2526177.1"
                     /translation="MPKLRLIGLTLLALSATAVSHAEETRYVSDELNTWVRSGPGDHY
                     RLVGTVNAGEEVTLLQTDANTNYAQVKDSSGRTAWIPLKQLSTEPSLRSRVPDLENQV
                     KTLTDKLTNIDNTWNQRTAEMQQKVAQSDSVINGLKEENQKLKNELIVAQKKVDAASV
                     QLDDKQRTIIMQWFMYGGGVLGLGLLLGLVLPHLIPTRKRKDRWMN"
     gene            51323..52624
                     /gene="ygiF"
                     /locus_tag="RN951_001147"
     CDS             51323..52624
                     /gene="ygiF"
                     /locus_tag="RN951_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic triphosphatase"
                     /protein_id="HDX2526178.1"
                     /translation="MAQEIELKFIVNHSAVEALRDHLNTLGGEHHDPVQLLNIYYETP
                     DNWLRGHDMGLRIRGENGRYEMTMKVAGRVTGGLHQRPEYNVALSEPTLDLAQLPTEV
                     WPNGELPADLASRVQPLFSTDFYREKWLVAVDDSRIEIALDQGEVKAGEFAEPICELE
                     LELLSGDTRAVLKLANQLVSQTGLRQGSLSKAARGYHLAQGNPAREIKPTTILHVAAK
                     ADVEQGLEAALELALAQWQYHEELWVRGNDAAKEQVLAAIGLVRHALMLFGGIVPRKA
                     STHLRDLLTQCEATIASAVSAVTAVYSTETAMAKLALTEWLVSKAWQPFLDAKAQSKM
                     SDSFKRFADIHLSRHAAELKSVFCQPLGDRYRDQLPRLTRDIDSILLLAGYYDPVVAQ
                     AWLENWQGLRHAIATGQRIEIEHFRNEANNQEPFWLHSGKR"
     gene            52647..55487
                     /gene="glnE"
                     /locus_tag="RN951_001148"
     CDS             52647..55487
                     /gene="glnE"
                     /locus_tag="RN951_001148"
                     /EC_number="2.7.7.42"
                     /EC_number="2.7.7.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional [glutamate--ammonia
                     ligase]-adenylyl-L-tyrosine
                     phosphorylase/[glutamate--ammonia-ligase]
                     adenylyltransferase"
                     /protein_id="HDX2526179.1"
                     /translation="MKPLSSPLQQYWQTVVERLPEPLAEKSLSAQAKSVLTFSDFVQD
                     SVIAHPEWLTELESQSPQADEWQHYAAWLQEALSNVSDEAGLMRELRLFRRRIMVRIA
                     WAQTLALVTEESILQQLSHLAETLIVAARDWLYDACCREWGTPCNAQGEAQPLLILGM
                     GKLGGGELNFSSDIDLIFAWPEHGCTQGGRRELDNAQFFTRMGQRLIKVLDQPTQDGF
                     VYRVDMRLRPFGESGPLVLSFAALEDYYQEQGRDWERYAMVKARIMGDSEGVYANELR
                     AMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLTDNIKLGAGGIREIEFIVQVFQ
                     LIRGGREPSLQSRSLLPTLSAIAELHLLSENDAEQLRVAYLFLRRLENLLQSINDEQT
                     QTLPSDELNRARLAWAMDFADWPQLTGALTAHMTNVRRVFNELIGDDESETQEESLSE
                     QWRELWQDALQEDDTTPVLAHLSEDDRKQVLTLIADFRKELDKRTIGPRGRQVLDHLM
                     PHLLSDVCAREDAAVTLSRITALLVGIVTRTTYLELLSEFPAALKHLISLCAASPMIA
                     SQLARYPLLLDELLDPNTLYQPTATDAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQ
                     LLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWVQMVARYGKPNHLNEREGRG
                     FAVVGYGKLGGWELGYSSDLDLIFLHDCPMDAMTDGEREIDGRQFYLRLAQRIMHLFS
                     TRTSSGILYEVDARLRPSGAAGMLVTSAEAFADYQKNEAWTWEHQALVRARVVYGDPQ
                     LTAHFDAVRREIMTLPREGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIE
                     FITQYLVLRYAHEKPKLTRWSDNVRILELLAQNDIMEEQEAMALTRAYTTLRDELHHL
                     ALQELPGHVSEDCFTAERELVRASWQKWLVEE"
     gene            55535..56968
                     /gene="hldE"
                     /locus_tag="RN951_001149"
     CDS             55535..56968
                     /gene="hldE"
                     /locus_tag="RN951_001149"
                     /EC_number="2.7.1.167"
                     /EC_number="2.7.7.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     D-glycero-beta-D-manno-heptose-7-phosphate
                     kinase/D-glycero-beta-D-manno-heptose 1-phosphate
                     adenylyltransferase HldE"
                     /protein_id="HDX2526180.1"
                     /translation="MKVTLPEFERAGVMVVGDVMLDRYWYGPTSRISPEAPVPVVKVN
                     TIEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKSLADVNVKCDFVSVPTHP
                     TITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALSSIGALVLSDYAKGALASV
                     QQMIQLARKAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVVGKCKTEEEIVERGMK
                     LIADYELSALLVTRSEQGMSLLQPGKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAA
                     GNSLEEACFFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMTEEELKLAVAA
                     ARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGDSRPVNP
                     LEQRMIVLGALEAVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSKEVWANG
                     GEVLVLNFEDGCSTTNIIKKIQQDKKG"
     gene            complement(57088..57147)
                     /gene="ibsE"
                     /locus_tag="RN951_001150"
     CDS             complement(57088..57147)
                     /gene="ibsE"
                     /locus_tag="RN951_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsE"
                     /protein_id="HDX2526181.1"
                     /translation="MMKLVIILVVLLLLSFPTY"
     gene            complement(57463..57522)
                     /locus_tag="RN951_001151"
     CDS             complement(57463..57522)
                     /locus_tag="RN951_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HDX2526182.1"
                     /translation="MMKLVIILIVLLLVSFAAY"
     gene            complement(57763..59424)
                     /locus_tag="RN951_001152"
     CDS             complement(57763..59424)
                     /locus_tag="RN951_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HDX2526183.1"
                     /translation="MDDIVNSVPSWMFTAIIAVCILFIIGIIFARLYRRASAEQAFVR
                     TGLGGQKVVMSGGAIVMPIFHEIIPINMNTLKLEVSRSTIDSLITKDRMRVDVVVAFF
                     VRVKPSVEGIATAAQTLGQRTLSPEDLRMLVEDKFVDALRATAAQMTMHELQDTRENF
                     VQGVQNTVAEDLSKNGLELESVSLTNFNQTSKEHFNPNNAFDAEGLTKLTQETERRRR
                     ERNEVEQDVEVAVREKNRDALSRKLEIEQQEAFMTLEQEQQVKTRTAEQNARIAAFEA
                     ERRREAEQTRILAERQIQETEIDREQAVRSRKVEAEREVRIKEIEQQQVTEIANQTKS
                     IAIAAKSEQQSQAEARANLALAEAVSAQQNVETTRQTAEADRAKQVALIAAAQDAETK
                     AVELTVRAKAEKEAAEMQAAAIVELAEATRKKGLAEAEAQRALNDAINVLSDEQTSLK
                     FKLALLQALPAVIEKSVEPMKSIDGIKIIQVDGLNRGGAAGDANTGNVGGGNLAEQAL
                     SAALSYRTQAPLIDSLLNEIGVSGGSLAALTSPLTSTTPVEEKAE"
     gene            complement(59451..60080)
                     /locus_tag="RN951_001153"
     CDS             complement(59451..60080)
                     /locus_tag="RN951_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1449 family protein"
                     /protein_id="HDX2526184.1"
                     /translation="MILFADYNTPYLFAISFVLLIGLLEIFALICGHMLSGALDAHLD
                     HYDSITTGHISQALHYLNIGRLPALVVLCLLAGFFGLIGILLQHACIMVWQSPLSNLF
                     VVPVSLLFTIIAVHYTGKIVAPWIPRDHSSAITEEEYIGSMALITGHQATSGNPCEGK
                     LTDQFGQIHYLLLEPEEGKIFTKGDKVLIICRLSATRYLAENNPWPQIL"
     gene            60349..60549
                     /gene="glgS"
                     /locus_tag="RN951_001154"
     CDS             60349..60549
                     /gene="glgS"
                     /locus_tag="RN951_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface composition regulator GlgS"
                     /protein_id="HDX2526185.1"
                     /translation="MDHSLNSLNNFDFLARSFARMHAEGRPVDILAVTGNMDEEHRTW
                     FCARYAWYCQQMMQARELELEH"
     gene            complement(60592..61656)
                     /locus_tag="RN951_001155"
     CDS             complement(60592..61656)
                     /locus_tag="RN951_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX2526186.1"
                     /translation="MRYLLIVIIFIIGFSALPVWAMDCYAEHEGGNTVVIGYVPRISI
                     PSNGKKGDKIWQSSEYFMNVFCNNALPAPSPGEEYPSAWTNIMMFLPGGQDFYNQNSY
                     IFGVTYNGVDYDSTAPNAIAAPECIDIKGAGTFNNHYKNPAVCSGGPEPQLSVTFPAR
                     VQLYIKLAKNANRVNKNLVLPDEYIALEFKGMSGAGAIEVDKNLTFRIRGLNNIHVLD
                     CFVNVALEPADGVVDFGKINSRTIKNTSVSETFSVVMTKDPGAACTEQFNILGSFFTT
                     DILSDYSHLDMGNGLLLKIFHKDGTATEFNRFSQFASFSSSSAPSVTAPFRAELSANP
                     AETVVEGPFSKDVILKITYN"
     gene            complement(61658..62407)
                     /locus_tag="RN951_001156"
     CDS             complement(61658..62407)
                     /locus_tag="RN951_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417519.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDX2526187.1"
                     /translation="MRYLNTKNLIAAGVLLACMSSIAWGAIIPDRTRIIMNESDKGEA
                     LKLTNQSKNLPYLAQTWIEDTKGNKSRDFIVTVPPMVRLNPSEQIQIRMITQEKIAQL
                     PKDRETLFYFNVREIPPKTDKKNVMQVTMQHALKLFWRPKAIELEDDGVMTYEKVEII
                     RRNDGSIRFNNKMPYHVTLGYIGTNGVTMLPQTQSLMVTPFSYANTQFKNVPSTFQVG
                     YINDFGGLSFYEINCPTVNNSCNVSVAKRDK"
     gene            complement(62423..64927)
                     /locus_tag="RN951_001157"
     CDS             complement(62423..64927)
                     /locus_tag="RN951_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001480735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDX2526188.1"
                     /translation="MYKKLKLTTISELIKNIYCSLSVIIIGCASAYAVEFNKDLIEAE
                     DRENVNLSQFETDGQLPVGKYSLSTLINNKRTPIHLDLQWVLIDNQTAVCVTPEQLTL
                     LGFTDEFIEKTQQNLIDGCYPIEKEKQITTYLDKGKMQLSISAPQAWLKYKDANWTPP
                     ELWNHGIAGAFLDYNLYASHYAPHQGDNSQNISSYGQAGVNLGAWRLRTDYQYDQSFN
                     NGKSQATNLDFPRIYLFRPIPAMNAKLTIGQYDTESSIFDSFHFSGISLKSDENMLPP
                     DLRGYAPQITGVAQTNAKVTVSQNNRIIYQENVPPGPFAITNLFNTLQGQLDVKVEEE
                     DGRVTQWQVASNSIPYLTRKGQIRYTTAMGKPTSVGGDSLQQPFFWTGEFSWGWLNNV
                     SLYGGSVLTNRDYQSLAAGVGFNLNSLGSLSFDVTRSDAQLHNQDKETGYSYRANYSK
                     RFESTGSQLTFAGYRFSDKNFVTMNEYINDTNHYTNYQNEKESYIVTFNQYLESLRLN
                     TYVSLARNTYWDASSNVNYSLSLSRDFDIGPLKNVSTSLTFSRINWEEDNQDQLYLNI
                     SIPWGTSRTLSYGMQRNQDNEISHTASWYDSSDRNNSWSVSASGDNDEFKDMKASLRA
                     SYQHNTENGRLYLSGTSQRDSYYSLNASWNGSFTATRHGAAFHDYSGSADSRFMIDAD
                     GTEDIPLNNKRAVTNRYGIGVIPSVSSYITTSLSVDTRNLPENVDIENSVITTTLTEG
                     AIGYAKLDTRKGYQIMGVIRLADGSHPPLGISVKDKTSHKELGLVADGGFVYLNGIQD
                     DSKLTLRWGDKSCFIQPPNSSNLTTGTVILPCISQN"
     gene            complement(64987..65496)
                     /locus_tag="RN951_001158"
     CDS             complement(64987..65496)
                     /locus_tag="RN951_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like protein"
                     /protein_id="HDX2526189.1"
                     /translation="MILSNNVFADEGHGIVKFKGEVISAPCSIKPGDEDLTVNLGEVA
                     DTVLKSDQKSLAEPFTIHLQDCMLSQGGTTYSKAKVTFTTANTMTGQSDLLKNTKETE
                     IGGATGVGVRILDSQSGEVTLGTPVVITFNNTNSYQELNFKARMESPSKDATPGNVYA
                     QADYKIAYE"
BASE COUNT        15785 a        16621 c        17128 g        16003 t
ORIGIN      
        1 agtaaattat tcattcatca acataatgat aaaagccgga tgagtcagac atccggcgag
       61 cagatttgtt ttaaggttcc agttttggat ctggtccaaa gcggttttcg cctggcgtac
      121 ccgcctggca gttaaagacg atgataataa gccagccgat aaacgggatt aagaatagca
      181 gtgcccacca cgccgagcgg tcggtgtcgt gcaggcggcg gaactgaacc gcccaccacg
      241 gtaaaaacac cagaataccg tagattgtcg tcaggatgcc ttcgccacca gcgcgttgcc
      301 agcctaacat tttatccagc agccccagca cgaacgtaaa gatgatgttg accagaataa
      361 acatccagta ctctttgcgc cgcgcacgac cccggaaacc gacataattt tttagtactt
      421 tcagatacca gtccattttt gcctcaattt tgctcaatca cttgttttta aagcagcaaa
      481 ttaagaatag acgtgaatga aatggcagta aatattcgtt caaggaatta ataaagtgcc
      541 gtgaaggcgc gctaagactg atgacaagcg caaaatcgcc agatgcgcta cgcttatctg
      601 gtctgcgcgg gttatgcaat ctattgaatg tacaatgttt tgtatgtcag ataaggcgtt
      661 catgccacat ccgacatgaa caacatgcac ttagctaatt atcagaggca cctcgtaagg
      721 tgcctttttt taaccgaagc gaacatctcg tccatgcggt tcatcgagat cctgccacgg
      781 accaattgaa ataatccccg tagggttgat ggtcttatgg ctgcggaagt aatgattacg
      841 gatatgatcg aaattgactg tttcggcgat ccccggcatc tggtagatat cgcgcagaaa
      901 accgtacaga ttcaggtaat cgctgatgcg gtgcttatca cacttgaagt gggtcacata
      961 caccggatca aaacgcacca gcgtagtcca caggcgaata tcggcttcgg ttagctggtt
     1021 gccggtcagg taacgatgct ggcctaaaat ctgctccagt cgtgccagcg attcaaacac
     1081 tttcgccacc gcctcgtcgt aagcttcctg gctggtggca aaaccagctt tatacacgcc
     1141 gttgttaacg gtgtcataaa tccagccgtt aagttcgtca atttttgttt gcagggctgg
     1201 agggtagtaa tcacccgctt tcgcgcccag cgcatcaaac gcggtattga acatgcggat
     1261 gatttctgct gattcgttgc tgacgatggt gtggttcttt ttgtcccaca gcacgggaac
     1321 agtaactcgt ccgctgtagt gtggatcggc gtggagataa agctgataca gaaattcatt
     1381 ttgatagagc gtgtctccgg ttgctcccgg aaaactgtca tcaaaggtcc aaccgttttc
     1441 cagcatcagc gggttcacta cggaaacgga aataaacggt tccagtcctt tgagtttgcg
     1501 catgatcagt gtgcggtgcg cccacgggca ggcgagtgaa acatagagat gataacgatc
     1561 tttctctgcg ataaaaccgc ctgtgccagt ggggccagga gcgccatcgg cagtgagcca
     1621 gttacgaaat gcggaagctg aacgttgaaa tttaccgccg gtagatttgg tatcgtacca
     1681 ggtgtcatgc cagacgccgt caatcagttg acccattttt ctctcctcca atagcaaaaa
     1741 cgaggagctt cctcctcgtt ttttatcgtt aagtatagcg cgtgcttacc actttttatt
     1801 cagcaggcgg tcgatgctat acgcgcccgg accggtaatt gccagcagca ggaatccgcc
     1861 agaaattgtc aggtttttca tgaacatcag cgagttgacg ccttcagcaa agttgctgtg
     1921 aaataaaaat gccgtcagca gcgtaaagcc cgcagtaaac agggctgtgg tgcgagtcag
     1981 gaaaccgaac aggattgcca gaccaccacc aaactcaagc agaatcacca gcggcagcat
     2041 aaaacccggg acgcccattg cttccatata ttgttgggta cccgcgtagc cagtaatttt
     2101 tccccagcca gcggtaataa acagaatcgg cattaaaatg cgcgctacca gtacaccaac
     2161 atcttctaat tttttcatca tactctccac tgcgccactc aggctgctga ttgttttttt
     2221 gtgcaatggc gcggtattag cgtcgttgct gtcgatggag agaatcataa acgtggtgaa
     2281 tgatgattgt tagcaaggaa aactgtcaaa aatcttcaaa aaatttgagg gataaggccg
     2341 gaatggctcc ggccagaggg aagttaaccg cgaagctgtt gctgcttgag ggtcgtttta
     2401 accagacgcc aggcgctcca tacgccaaaa ccgcgtctgg cccagcggac cagcatatta
     2461 ggatggcgaa tcgtccagat cgccatcacg ctactgccaa ccagcgccca ggagcgcaga
     2521 cttagcagca tattccagcg acgatcgtaa gcgcctgttg tctccagcca ttcacgacga
     2581 ctggcggaaa gatccagccg ttgttgctgg atctggctaa gcagttgcgc cttacgtcgt
     2641 tcacgttcga ctttactgct cacgggactc ctcctcgagc agctgccgat cgtttgctaa
     2701 ctcatggcgt gtatggcgca gcaacgtaga cttacgcgat ttacgtagcg tccagatacc
     2761 gccaatcagt gccagtagca gcaacaccac ggtggtggca atcatcgcat tcaggcgata
     2821 ttgcgggtca accgcccaaa taattagcac catcaggctc ataagaccaa atgcagcgaa
     2881 aagcatcgtc aggcccagca tcagtaaaag ttgaaagaga ttcgcttttt cctcttccag
     2941 ctccaccacc gccagccgca gacgtgtctc taccatttca accatgatag aaacaattcg
     3001 ctgcccgatg cccagaacgc ttttaccggg cccttgtgcg tgatgagtgt ccgccataat
     3061 taacgacgcg acagcagaac gccgagcact acaccgattg cagcgccaat gcccacgccc
     3121 gtccacggat tttcgcgcac atactcatcg gcacgcgccg ccgcgacacg ggtttgtttg
     3181 gcaatggcat caccggtttc acccaggcga taacggctct gtttcagtgc ctgctccgct
     3241 ttgctacgaa tcttactcaa ctcttctttc gacttctcgc cagatgagct aagcacctct
     3301 tccagcgtat cggaaaggga tttcaactca gcacgcagat gttccgtagt gtgttctttc
     3361 gacatagttt tctccaggtg agtaagtagt gcctattgtg agttagtagt cgcgcgcttc
     3421 cagctttttc agctcttcct gcgcttctgc cagtttccgt tcgcgtttgg caatcttatc
     3481 ggcatcgcct ttttgcttcg cctcggctaa atcttgctgg cgttccgcca cctcatcttt
     3541 ctgctttgcg attttcttct gatgatcggc acgcagctgg ctatctgaac agttggcccg
     3601 gacttcactc agggctttat tcagaccgtc aatacgattc tggttttggt gtttttcggc
     3661 atagctgatc tccttaagga tattttgctc cttttcctga cacagggtag tggcataact
     3721 accggcacta agagcaaaga gagaaacagc taaagcgatg cggtatttca ttcttgaacc
     3781 ttccattgtg attcggacct attacaaagg aacgattgtc cagacaacga agcggtagtg
     3841 ttaaccaccg cctcattaat catagacagt tacggtgaaa tcaccaaagt gagtgatatg
     3901 tttcggataa caggaagtta tccgaagcga tgagagttat cccgtaaccg ggtcagccac
     3961 tgcatagcct gactgttatt gtcctgctgc gcaatgatgt agccatgggg caatgttctg
     4021 tcgaggaccg cttttgcggc ggcgctctgg tcgctggagt caaatgtaat taacagagtg
     4081 tcgtttttgg gggtgatact tttgaaagga atgccatgag cgtcaaggtg atgccagatt
     4141 gaaaaaccgt ctggcatcgt tgtgccttga tgaacggcac gaatcgccag cgtagactct
     4201 tgctggcgaa ccgcggacca ggccagcaac agcgtgccga ccagaagtaa aacagcgccg
     4261 gaccaggcta gctggcgaag cgacatgcga ggtatttgca tcccttaccc ccgatttcca
     4321 tatttctttt tccataacac gaccagagaa cctgccaggc caaacaccag cagcaccacc
     4381 gggagcagca tcaggcatga catcagctgg tcctcgtact ttaaaaatac cggcgttttg
     4441 ccgagcatgt aacccagagt tgtcaggatc aatacccaca gcagaccgct catccagttg
     4501 aaaaactgaa agcgcgcgtt attcagccct gataacccgg caatcgtcgg cagcagtgtt
     4561 ctgacaaacg caataaagcg accaattaac agcgccgata aaccgtgttt atgaaaaaga
     4621 tggtgtgcgc gttgatgata atgcgcgggt aaatgagata gccagttttg tacggtgcgg
     4681 gtattgccca gccatcgccc ctgaatatag ctgacccagc agccgaggct ggcggcaacg
     4741 gtcagcagca gaatcgtttg cggatagccc atcgcgcctt tcgcaatcaa cacgccgacc
     4801 aataccagta aactgtcgcc cggtaaaaag gccgccggaa gcaagccgtt ttcaaggaac
     4861 aaaattacaa acaagacaaa atacaacatg ccaatcatcg atggattggc cagggtttca
     4921 aaatcctgcg cccacagggc ttgcagcaat tgggtcaaaa gttccattca ttattcctgg
     4981 tgaatcggtt aacgccacgc tggttttaaa agatgcacta ccgcaatgtt attgctgttt
     5041 tggtatgttc tgcgggtttg atacatcaac acagcctgaa ctattccctg ttaaatcgtg
     5101 agataagaaa gcattcaaaa acataaattc aaattgaatc taattgtaac aaaggtcaac
     5161 gttgttcgtt atcaaaatta catgtccgtg gagtctgatt ttgctgaatg caggggaggg
     5221 tggcgagagg atttacacag gctgacactt tatacttttc gcttaccgac gagacaaaca
     5281 ggcgcattgc agcgcctgtc ggacaggaat ttcatttact gccgctggtg gctgtatcga
     5341 gatgcaccac cgggttttcg gcgaatagat agcggtcggc attgaactcg aagtcgtcgc
     5401 tggtttcgtt aaataacatg atcttggtgt tttccagatg ctgccacatt gccagcttag
     5461 cagcatgagg atctttgcga atcagcgcct tgaggatttg atcgtggtca tcacaccagt
     5521 tatcgacggt acgggaatca atgtgttcgt gcagtttttt ccagtacggg ttatgactac
     5581 gctgggtcca cattttttcc acgatagccg ccagggcgga gttctgcgtc gccagagcga
     5641 cctgaatgtg gaactgcaaa tcccactcgg aatcacggaa gcattgttcg ccgcgcgcct
     5701 gttcctgaat ggccatcagt ttcatgatgt cctgtttcgt tacctgagtt gccgcgaatt
     5761 cggcaatatt actttcgatg agctggcgag cctgaagcaa ctcaaacgga ccgtaattgg
     5821 cgaattccat attattgtca gccgcctgct gatggcgcgg ctggttggaa accacatgaa
     5881 tacctgaacc tttacgcact tcgacatagc cttcaacttc cagcatgatg atggcttcac
     5941 gaactaccgt acggctgacg ttcttttcat cggcaataaa gcgttctgca ggcagtttat
     6001 cacccaccag atagacgccc tgttcgatgc gctctttcag gtcagcggca agttgttgat
     6061 acaaacggcg tggttcagtg atttccatat gcgctccagg catgatacgg cagactatat
     6121 ttgttatacc acttttgcga gtttagctct actcgcagtg atgaaaaagc cgcctgagaa
     6181 ggcggctttg aagggaaact aaaacttaca cgaaacgtta atgttgcggt gcgggatcgt
     6241 tatgtgtttc ctgcgccacc tcaatcgccg gtttgttctg caacacggtc cagataacca
     6301 gcgcacctaa caggtcgaac actgccagaa ctgcgaacag cgggctgaag ccgatggtgt
     6361 cagccagtgc accgacaacc agcgcaaaca gcgtacttgc cagccatgcg gacatcccgg
     6421 ttaaaccgtt tgccgttgcc acttcgttac gaccaaacac atcggaagag agcgtaatca
     6481 gcgcgccaga cagtgcctgg tgggcaaaac caccgataca cagcagcata attgcgacat
     6541 acgggttggt gaacaggccg atcatacccg ggccaatcat cagcactgca cccagcgtta
     6601 cgaccatctt acgggaaacg atcaggttca caccaaacca acgctggaac agcggcggca
     6661 ggtaaccacc gaggatacaa ccgaggtcag caaacagcat cggcatccag gcgaacatcg
     6721 cgatctcttt caggttaaag ccgtaaactt taaacatgaa cagcgggatc cacgcgttaa
     6781 aagtacccca ggccggttct gccaggaaac gcggcagcgc gataccccag aactgacggt
     6841 tacgcaggat ctgaccaacg gacattttct tcgccgtgct cacctggtgc tgggcttcct
     6901 gaccattaat aatatagtcg cgttcttcat cggtcagatg cttctggtcg cgcggatgtt
     6961 tatagaaaat cagccatgcc atcgcccaga taaagctcaa tgcaccggag atgataaatg
     7021 ccatctgcca gctgtgcatt acgattgccc ataccaccag cggcggcgca atcatcgcac
     7081 caatcgaaga acctacgtta aagtagccta ctgcgatgga acgctctttc gccgggaacc
     7141 attcggagct ggctttcaga cccgccggga tcatcgctgc ttccgcggca ccgaccgcac
     7201 cacgagcaac agccaggcca ccccagctac ctgccagcgc ggttgcacca cagaacacgg
     7261 cccacagcac agcaaacatt gcataaccga ttttcgtacc cagcacatcc agtacataac
     7321 ctgctaccgg ttgcatgacc gtataagcag cagaataggc tgcgatgata taggaatact
     7381 gttgggtgga gatgtttaac tcttccatca gagttggcgc agctgccgcc acagtgttac
     7441 gcgtcaggta accaagcacg gtgccgagcg tcaccagtgc gatcatatac caacgtaacc
     7501 ctttaatttt acgcatgtaa aacctcatcg ttttgttata tccgcaggaa gcgcggccat
     7561 catcccgcca gaggctgaag atgttagtta cgaccgggta accgaaaaaa aaccggcacg
     7621 ccccgaacgt tgccatgaaa gtttcgtgct aattcggctt ccgtaccggt taacccgatt
     7681 catctaacaa atgaatgaat cggcaatttg cattccgtcg acttatgatt tgcgacggca
     7741 gaaagataac ttgtcataca actttaaaag gtgagagcca tcacaaatgt gggaatattt
     7801 gtagggacat tacctgacga cagcaaggcc agtactggcg cggcctgcag cgagatttac
     7861 cactttgaga gtaatttttt taactacgtt tattgatcta actcacgaaa atatcttcgg
     7921 actctggaaa ttggtgtgat aactttgtca gcatcgcacc ataagcaagc tagctcactc
     7981 gttgagagga agacgaaaat gactccgttt atgactgaag atttcctgtt agataccgaa
     8041 tttgcccgcc gtctgtatca cgactacgca aaagaccagc cgattttcga ttaccattgc
     8101 catttgccgc cgcagcagat tgcggaagac tatcgtttta aaaacctgta tgacatctgg
     8161 ctgaaaggcg atcactacaa atggcgcgct atgcgtacca acggtgtggc cgagcgtctg
     8221 tgtaccggtg atgcgtctga ccgtgaaaaa tttgacgcct gggcggcgac tgttccgcac
     8281 actatcggca acccgttata ccactggacg cacctcgaac tgcgccgtcc gtttggtatc
     8341 actggcaaat tgctttctcc gtcaactgcc gataaaatct ggaacgaatg taacgaactg
     8401 ctggcgcagg ataacttctc cgcgcgcggc atcatgcagc agatgaacgt gaaaatggtc
     8461 ggcaccaccg atgacccgat cgattctctg gagcatcacg cagagatcgc caaagacggc
     8521 tctttcacca tcaaagtgct gccgagctgg cgtccggaca aagccttcaa catcgaacag
     8581 gcgaccttta acgactacat ggcgaagctg ggcgaagttt ccgataccga cattcgccgc
     8641 tttgctgacc tgcaaactgc cctgaccaaa cgtctggatc acttcgccgc tcacggctgt
     8701 aaagtgtctg accacgcgct ggatgtggtg atgtttgctg aagcgaacga agcggaactg
     8761 gacagcattc tggcgcgccg tctggctggc gaaaccctga gcgagcacga agtggcgcag
     8821 ttcaaaactg cggtactggt gttccttggt gccgaatatg cacgtcgcgg ctgggtacag
     8881 cagtaccaca ttggcgcgct gcgtaataac aacctgcgtc agttcaaact gctggggccg
     8941 gatgtaggct ttgactccat caacgaccgt ccgatggcgg aagagctgtc taagttgctg
     9001 agcaagcaga atgaagaaaa cctgctgccg aaaaccattc tgtactgcct gaacccgcgc
     9061 gataacgaag tgctgggcac catgatcggt aacttccagg gcgaaggtat gccgggcaaa
     9121 atgcagttcg gttccggctg gtggtttaac gatcagaaag acggtatgga acgtcagatg
     9181 acccaactgg cgcagctcgg tctgctgagc cgctttgtcg gtatgctgac tgacagccgt
     9241 agcttcctgt catacacccg tcacgaatac ttccgccgca ttctgtgcca gatgatcggt
     9301 cgctgggtgg aagcgggcga agcaccggcg gacatcaacc tgctgggcga gatggtgaaa
     9361 aatatttgct ttaacaatgc gcgtgactac ttcgccattg aactgaacta aggtctgggg
     9421 ttgatatgca atacatcaag atccatgcgc tggataacgt cgcggtcgct ttagcagatt
     9481 tggctgaagg cacagaagtc agtgtcgata accagactgt tacgctgcgc caggatgttg
     9541 ctcgtggaca taaatttgcg ttaacggata tcgcaaaagg ggccaatgtc atcaaatatg
     9601 gcctgccgat tggttatgca ttggcggata ttgcggcagg tgttcacgtt cacgcccaca
     9661 atacgcgcac gaatctgagc gatctggatc agtatcgcta tcaacctgat tttcaggatc
     9721 tgcctgcgca agcggcagat cgtgaagtgc agatctatcg tcgcgctaac ggcgatgtcg
     9781 gggtgcgtaa tgagctgtgg atcctgccaa ccgtgggctg tgtcaacggc atcgcgcggc
     9841 agatccagaa ccgttttctg aaagagacca acaacgccga aggtactgac ggcgtgttcc
     9901 tcttcagcca cacctacggc tgctcacagc tgggcgacga tcacattaat acccgcacca
     9961 tgctgcaaaa catggtgcgc cacccgaacg caggcgcagt gctggtgatt ggtctgggct
    10021 gtgaaaacaa ccaggttgcc gcattccgtg aaacgctggg cgatatcgat cctgaacgcg
    10081 ttcatttcat gatctgccaa cagcaggatg atgagatcga agccggaatc gagcatttgc
    10141 atcagctgta taacgtgatg cgcaacgata aacgcgagcc aggcaaactc agcgaactga
    10201 agtttggtct ggagtgcggt ggttctgacg gtctttctgg tattactgct aacccgatgc
    10261 tggggcgttt ctctgactac gtgattgcta acggcggtac taccgtactg accgaagtgc
    10321 cggagatgtt tggcgcagag cagttgctga tggaccattg ccgcgacgaa gcaacgtttg
    10381 aaaaactggt caccatggtc aacgacttca aacagtactt tattgcccat gatcagccga
    10441 tctatgaaaa cccatcgccg gggaacaaag cgggcggtat caccacgctg gaagacaaat
    10501 cacttggctg tacccagaaa gcgggttcca gcgtcgtggt tgacgtgctg cgttacggcg
    10561 agcgtctgaa aacgccaggg ctgaacttgt taagtgcgcc gggtaacgat gccgtagcga
    10621 ccagcgccct ggcgggtgcg ggctgccata tggtgctgtt cagtactggt cgtggcacgc
    10681 cgtatggtgg atttgtgccg acggtgaaaa tcgccaccaa cagtgaactg gcggcgaaga
    10741 aaaaacactg gatcgacttt gacgcgggtc agttgatcca cggtaaagcg atgccgcagt
    10801 tgctggaaga atttatcgac accatcgttg agtttgccaa cggtaagcaa acctgtaacg
    10861 agcgtaacga cttccgcgaa ctggcgatct tcaaaagcgg cgtaacgcta taaagtcgaa
    10921 atgagttgtt aataaaaaac ggcgtttcat aatgtgaagc gccgtttgct tttccatacc
    10981 tgctaaggat ttatcatgac cgcgtattgg ctggcccagg gcgtgggtgt catcgccttt
    11041 ctgattggta tcacaacatt tttcaatcgt gacgaacgtc gcttcaaaaa gcagctttcg
    11101 gtctatagcg ccgttattgg cgtacatttt tttcttctgg gcacctatcc cgctggtgcc
    11161 agtgccatcc ttaatgccat tcgtacattg attaccttac gcacgcgcag cttatgggta
    11221 atggcgattt ttattgtgct gactggcgga attggcctcg cgaagttcca tcatcctgtc
    11281 gaactattgc cggttatcgg cacgattgtc agtacctggg cgctattccg ctgtaaaggg
    11341 ctgaccatgc gctgcgtaat gtggttttca acgtgttgct gggtgattca caacttctgg
    11401 gcggggtcga taggcggcac gatgattgag ggtagttttc tgcttatgaa tggcctgaat
    11461 atcattcgtt tctggcggat gcagaaaagg ggaattgatc cgtttaaagt tgagaaaacc
    11521 ccttccgccg tagacgaaag gggttaaaca attaattacg cagggcgcta tttgccagac
    11581 gatcgtcttc tgcctggcaa gctgccgcag tgaacagcac gtcagttgaa gagttcagcg
    11641 cggtttcgca agagtcctgc aatacgccga tgataaagcc gacggcaacc acctgcatgg
    11701 cgatatcgtt cgaaataccg aacatattac aggccagtgg gatcagcagc agagaccccc
    11761 ccgccacgcc ggatgcgcca caggcacaca gagaagccac cacgctcaac agcagcgccg
    11821 tgggcagatc gaccggaata cccagcgtat taaccgcagc cagcgtcaac acggtaatag
    11881 tgattgctgc gcccgccata ttgatggtgg ctcccagcgg aatagaaacg gaataggtat
    11941 cgcgatccag attcagcttt tcacacagcg ccatattcac cggaatgttc gctgcagagc
    12001 tgcgggtgaa gaaggcatac acaccgcttt cgcgcaggca cagcagcacc agcgggaacg
    12061 ggttacgacg aattttccac cacaccagca atgggttaac caccagcgcc accagtaaca
    12121 tacagccaac cagcacgacc agcagttgcg cgtagcccca cagtgtggag aaaccggtgg
    12181 ttgccagggt agaagaaacc agcccaaaaa taccaatcgg tgcgaagcga atgaccagtt
    12241 tcaccataaa ggtaacggca ttcgacatat cgttaaccag gtttttggtg gtctcgttac
    12301 cgtgacgcag tgcgaagccg aggccgatcg cccacaccag aatcccgatg tagttacctt
    12361 tcagcagcgc gtcgatgggg ttggaaacca tgctcattac cagcccgcgc atcacttcga
    12421 caatgcctga cggcggcgaa atatcacccg cgctactgga taaatgcagg gtagaaggga
    12481 aggcaaagct gaagactact gcggccagag cagcagagaa ggtgcccagt agatagagga
    12541 acaaaatagg gcggatattg gttttctgcc cgtgctggtg gttagcaata gatgccatca
    12601 ccagcatcaa caccaggatg ggggcaacgg ctttcagtgc gccgacgaac aaagtaccta
    12661 acagaccaac agcttccgcc gcgggttttg agatccatgc cagaagaatc cccagaacaa
    12721 ggccgaccag gatttgtttt accaggctgc catgagccag acgccggaat agccccggtg
    12781 aacgttgcgt agtcattttt cgatcctttc attgtgttgt cgcacatccc tggtgcgttc
    12841 tgtcgacgca tctttcagga tgtaacaaag tgtttgcaag gtcgagtata aggaaagtta
    12901 cagcttcggg aagcgaaaaa tgctggattt taaagagagg tcatattttg aaacttaatg
    12961 gttacatttc ttttacataa aaataaagcc aacgtgcggc ttccagactg atgacaacat
    13021 caaaaaagga ctcggtcagt cccctcgccc cgtttgggga gagggttagg gtgaggggaa
    13081 caggccagca tcggtgcgaa aaattaccct caccccgacc ctctccctgg aagggagagg
    13141 gagaaaacgg tgctcatgtt aatgacaggg tacacggctt aggcagatta aaaattatcc
    13201 accccgctgc ttatcatgcc gataattcac ccaggcgttg ataataaacg tcatcaccag
    13261 aatgccaaac accacgccca gcgagacggc gattggaata tggtagaagt cgacaatcag
    13321 catcttgata ccgataaaca ccagaatcac cgccaggcca tatttgagca tcgagaaacg
    13381 ctctgctacg cccgccagca ggaaatacat cgcacgcagg ccgaggatcg caaacaggtt
    13441 tgaggtcagc acaatgaacg ggtcagtggt cacggcgaag atagccggaa tgctatccac
    13501 ggcgaaaatc acgtcgctca attccaccag aatcagtacc agcatcagcg gtgtggcgta
    13561 cagcaatcca ttcttacgca caaagaaatg ctcgttgtcg atggtgtcgg tcatgcgcaa
    13621 atgaccgcgt agccagcgca ccagcggctt gtcgccaatg cctgattcat cttcatgggc
    13681 gagcgccatc ttcacgccgg taaacagcag gaaggcaccg aagatataca ggatccagtc
    13741 gaactgcgaa attagccagc tgccagtgaa gatcatgatg gtacgcagaa caatcgcccc
    13801 gagcacgcca tacaccagca cgcggcgttg taatgccgcc ggaacagaga aatagctgaa
    13861 caacatcagc cagacaaaga cgttatcgac cgccagcgat ttctcaatca gataacctgt
    13921 gagaaaggcc agtgcctgtg gatcggcaac ggcgcgacct tcggtttgca ccagatacca
    13981 ccagaaagcg gcgttaaaca gtaacgacag cgtcacccag accagcgacc aggccgcagc
    14041 ctgtttcatg gtcatggcat gtgccccacg acgcccctgc aacaacaggt cgatagccag
    14101 cataatggcg acaacaacag cgaatccgcc ccatagcaac ggcgtgccga cagtattcat
    14161 agaagttcct tacacataaa aaaacggcca acgtcggaag acgtcagccg ctgcttttta
    14221 tgcatagacc tcgccttccg gcaaggtctc acttacaaca aaaaaggaat acgtctgcgt
    14281 attcctttcg ggttgcccgg tgaccggatg tgttttttca cacatcgtaa tgacgatcga
    14341 ccggcaatga agttactccc ctttgcaggt aacaaagtat gacagaccat tcagccagtc
    14401 aatggtctgt tacatacctt ttacactgtt ttactttggc aattatagtt ttacgctatc
    14461 tgccggaaaa atcaccccag tctggcggcg gatctcggtc agcagtttgg cggtgatgcg
    14521 actgaccgcc agccctggat gatccaccag atgctcatcc accagggtag cgaacagctc
    14581 tgcttcgtag agcatggtat taatatgctg cggctgggtg agatcctgca tttggctgcc
    14641 acgcggcacg aagcacactt tctggcattc agacagtttt tcaatcacca gcgatcctgc
    14701 ttcgccctga atctcgctcg ccaggacaga atcactgact tttgagtgct gcaaggtgac
    14761 gctgaaatca ccgtaatcca tcaccaccac gccctgggcg tcaacgccgc ttgccagcaa
    14821 actggcggtt gcctgcacgc ttttcggctc accaaataac gccaccgccg acgccagaca
    14881 gtaaaaaccg atatccataa ttgaaccgtt agagaatgcc ggattaaagg tgttgggatt
    14941 ctcaccatcc aggtaacgtt gataccgcga ggaatactgg caatagttga aaaagacttt
    15001 ccgcagtttg ccgactttcg gcagcgcctg gcgcaacaaa tgaaagttcg gcaggcaggc
    15061 ggttttaaat gcctcaaaca gcaccacctg attttcccgc gcacaggcaa tggcggcatc
    15121 cacttccgcc agattcgacg ccagcggttt ctcgcaaatc acattaattt tatggctaag
    15181 gaaaagttgt gtctgggaaa aatgcaggga attcgggctg gcaatataca ccgcgtcaat
    15241 ggcatcgctt tccgccatcg cttccagcga ggtaaacaga tgctcgacag aaaaatcatt
    15301 ggcgaagtgc tgggcctgtt caaggctgcg ggaatatacg gcggttaact tgtatttacc
    15361 gctctcatgg gcggcctcga cgaactggcg agtgatccag ttcgtaccaa tcacagcgaa
    15421 acgtatcata acgcgtggat actccataaa gggattctgt cgtcaatgta gcacgccttt
    15481 ttcatcttcg acgtgcgcag atacgcatta tttctgcgcc ggacagccat gctcactaaa
    15541 cggcccaatc atgaccgaag gcccgagata tttcggctgg cgatggagga ttttggcgtc
    15601 aatcacggcg ctgacacgag cgagtttctc ccgcagttga gtataaaaac cgtgcttcat
    15661 attgaggtct ggcgcgttaa aaccgatagc gtcgatgccg tactgttttg ccagccagat
    15721 ggcgcgttga ttatgaaatt cttgcgagat aatggtgata tggttttcac caaaaacctt
    15781 tttggcacgc actaccgaat ccagcgttga gaatccggca tagtcgcaga agatcacttt
    15841 tgctggtacg cctttagcga tcaaagcctg ctgcatacct gatgcttcat cgtaattttt
    15901 acgtccgtta tcgccactta ccagcagcca tttcactttt ccggcgtggt acaacgctgc
    15961 tgcggtatca atacgtcggg taaagtagcg attacccggc ctcgccccca gcaataaacc
    16021 cacgttacgc gccggaacgg cgttgacatc gctccaggtc agctgtttgc tggcgttgac
    16081 cattacgcga tcggcgataa ggatggtcgc tcctgccaca agtaacagta agcaggcaat
    16141 ctttagagtc cggcgagaaa aacaaatacg gagaagaagg cgggcaaatg cgcgcagcat
    16201 ggtcgttatc cttaacgaaa ggggggaggt cgattttagg cgctaaagaa agaaaagata
    16261 acgcctgaca tcattttcag attttgtcct gcccaagcga caactgcgtt agccacagcc
    16321 gggtgtcgaa ctcaagctgg tggtactgcg gctccatatg gcagcacaac tggtaaaacg
    16381 ctttgttatg ctctttctcc ttcaggtgcg ccagttcgtg caccacgatc atacgtaaaa
    16441 acggttccgg cgcgttgcga aacacagtag cgacgcggat ctctgctttt gctttcagct
    16501 tgccgccctg cacacgagaa acagcgctat gtaacccgag cgcgtttttt agcacatgga
    16561 tcttattgtc atacatcact ttattgatcg gcggggcatt acgcagaaac tgatttttca
    16621 gatcctgagt atattgccag agggctttat cggtggcgta gtcgtgtgtt cccggatagc
    16681 gttttgccag cacatcgccc agacgctgtt cgttaatcag cgttcgcacc tgggaaagta
    16741 gctgctcggg ataaccctga agataagtaa gattgttcat aaccgcccac gaaaaagaga
    16801 aaaagggtat actcacgcac ccttttcagg ggcaacgtcg aaattttatc attcaggagg
    16861 gccgatgagc cacttagaca acggtttccg ttcactgaca ctacaacgtt ttccggcgac
    16921 ggatgacgtt aacccgctac aggcgtggga agcggcggat gaatatttgc tgcaacagtt
    16981 ggacgacaca gaaatccgcg gcccggtgtt gatcctgaat gatgcctttg gtgcgttaag
    17041 ctgcgcgctg gcggaacata agccgtacag cattggcgac tcatacatca gtgaactggc
    17101 gacgcgcgag aatttacgcc tcaacgggat tgatgagtcg agcgtgaagt ttctcgacag
    17161 caccgccgac tacccgcaac agccgggtgt ggtgctgatc aaagtgccga aaacactggc
    17221 attgctggaa cagcaactgc gtgcgctgcg caaagtggtc acgtcggata cacgtattat
    17281 tgccggtgcc aaagcccgtg acattcacac ttccacgctg gagctgttcg agaaagtgct
    17341 cggcccgacc accactacgc tggcatggaa aaaagcgcgc ctgattaatt gcactttcaa
    17401 tgaaccgccg ctggccgatg cgccgcagac cgttagctgg aagctggaag gtactgactg
    17461 gactatccac aaccatgcga atgtcttctc ccgcactggg ctggatattg gcgcacgctt
    17521 ctttatgcaa catctgccag agaatctcga aggtgagatt gtcgatctcg gctgtggtaa
    17581 cggcgttatt ggcctgacgc tgcttgataa aaacccgcag gcgaaagtgg tgtttgtcga
    17641 tgaatcgccg atggcggtcg cttccagccg aatgaatgtt gaaaccaaca tgccagaggc
    17701 gttggatcgc tgcgagttta tgatcaacaa cgcgctctcc ggagtggagc ctttccgctt
    17761 taatgctgtg ctctgcaacc cgccgtttca tcagcaacat gcgctgaccg ataacgtcgc
    17821 ctgggagatg ttccaccacg cccgccgctg cctgaaaatc aacggcgaac tgtatatcgt
    17881 tgccaaccgt cacctggatt acttccataa actgaagaag attttcggca actgcaccac
    17941 catcgccacg aataataaat ttgtggtgct gaaaacagtg aagctggggc gtcgtcggta
    18001 agattgggag ttacctgccg gatgcggcgt taacgcctta tccggcctac gttcagcacg
    18061 ttactcccag gccggataag acgcggcaag cgtcgcatcc ggcaatgtct gcccagttct
    18121 ggaatcgcgc ttccataaaa caaaaaatcc ctgtcaccat cctctacatt ctcttgttta
    18181 gcgttgttca acgtttatgc tacatacgtg aagttatgac gcataaagaa tacgatttct
    18241 ttaccgctgt tcatcgtact aaggggaaaa aatgattgcg attgccgaca tcttgcaagc
    18301 aggagaaaag ctaactgcgg tggcaccttt tctggcgggt attcagaacg aggaacaata
    18361 cacccaggcg ctggaactgg tagatcatct gctgctcaac gatcctgaaa accccttgct
    18421 ggatctggtg tgtgccaaaa taaccgcgtg ggaagaatca gcgcccgaat ttgcggaatt
    18481 taatgccatg gctcaagcca tgcctggcgg tatagccgtg attcgtaccc ttatggatca
    18541 atatggttta accctttccg atctgccgga aattggcagt aaatctatgg tgtcacgcgt
    18601 tttgagcggg aagaggaaat taacgctgga acacgctaaa aaattggcaa cacgattcgg
    18661 catttctccc gccttgttta ttgattaacg cgacgtgccg gatgcgttgc atccggcgct
    18721 tcaaataacg atttaaatct ccagcgccag ccgtgttccc tgggcaattg cccgtcgtgc
    18781 gtccagctcc atagccacat cgcagccgcc aattaaatgc acagttttcc cgctatcaat
    18841 cagcggttgc gccagcgcgc ggtttggctc ttgccctgcg cagatcacca cattgtccac
    18901 tgctaatacc tgcgtttcgc cgttgatcac cacatgcagc ccgtcatcgt caatcttctg
    18961 ataacttacg cttgggatca ttttcacacc ccgcgagagc agggtggtgc gatggatcca
    19021 gccggtggtt ttgcctaacc cctgtcccgg tttgctggct ttgcgctgga gcatcacaat
    19081 ttgccgtggg ctacgcggga tctgcattcc ctgcgggctt aagccaccag cctgttgtag
    19141 gctgctgtcg atcccccact cattacagaa cctggcgata ttctggctgg tggattcgcc
    19201 cggctgactt aaatacatcg ccgtatcaaa accaatcccg ccacaaccga tgatggcaac
    19261 cttgttgcct accggcgctt tgtcgcgcag tacatcgaga taactcaata ccttcggatg
    19321 atcgatcccg tcgataggcg gaacgcgcgg cacgatccca ctggcgagga tcgtttcatc
    19381 gaacgcctgt aactgatccg ccgtcacggt gtgattgagt ttcagcgtca cgcccgtcac
    19441 ttcgatcatc cggtggtaat agcgcagcgt ttcgtaaaac tcctctttgc cggggatctg
    19501 tttggcgata ttaaactgcc cgccgatctc gctgtgggca tcaaacaatg ttacctgatg
    19561 cccacgcgcc gccgcgttaa tggcaaacgc cagcccagca ggtcccgcac cgaccaccgc
    19621 cagatttttt ttctgcacgg caggaaggat tggcattttg gtttcgtggc aggcgcgagg
    19681 attcaccagg cacgaggtga ctttgccaac gaagatctga tcgaggcagg cctgattgca
    19741 gccaatgcag gtgttgatct catcggctcg ccccgattgc gcttttgaca gcagttccgc
    19801 atcagcaaga aacggtcgtg ccatcgatac catatcggca tcgccgcgcg agagaatatc
    19861 gtcggcaacc tgcggatcgt taatccggtt ggtggtcacc agcggcagcg agacgtggcc
    19921 tttcagtttg cgcgtgaccc aagtaaatgc gccgcgcggc acgggcgtgg caatggtcgg
    19981 aatacgtgct tcatgccagc caatgccggt gttgataatg gtcgcgcccg ccgcttcaat
    20041 ggcctgcgcc agttctaccg tttcggcaaa agtgccgccg ccttcgacca ggtcgagcat
    20101 cgacaaccgg tagataataa tgaagtcgtt gccgacgcgt tcgcgcaccg tacgcactac
    20161 ttctacggca aatcgcatcc ggttgcggta atcgccgccc cactggtcac tacgctgatt
    20221 ggtgcgcagc gtcagaaatt cgttgatcaa atacccttcg gaccccatta cctctacacc
    20281 gtcgtatcct gcctcccgtg ccagttgcgc gcagtgggcg aaatcgtcga tcagttgcag
    20341 gatctcttca tgcgtgagtt cgtgaggaac gaaacggttg atgggggcct gcaatgcgga
    20401 gggagcgacc agatgcggtt ggtagctgta gcgcccggta tgcaaaattt gcagggctat
    20461 tttgccgcct tcctgatgta ccgcttcggt aatggtgcga tggtgtggga tctggctggc
    20521 gtcgttgagc attgcgccac cttccatgcc aacgcctgtt aaatctggtg caatgccgcc
    20581 gctgacaatc agcgccacgc cgtgacgggc gcgttcggca taaaacgctg ccagccgctc
    20641 ggcaccgtcc gggtattcct ccagcccggt gtgcattgag cccatcaaca cgcggttttt
    20701 taacgtggta aaacctaaat ccagcggggc gaacagcgac gggtagctca taaaattgtc
    20761 cagtatgtaa aataattgtt atgtggtcgg atgagttcta atttagccgt cgccggagaa
    20821 aagggaaaag gggagtgcgg ggtttgtgat gggattcaaa aagaatacgc ccggtggtaa
    20881 cgccggatgc gacgcttgcc gcgttttatc cggcctgggg gattgcacat gtagggcgga
    20941 taaggcgttc acgccgcatc cgccagtggc acggtgcaga tgccggatgc gacgcttgtc
    21001 gcgttttatc cggccaggag gattgcacat gtagggcgga taaggcgttt acgccgcatc
    21061 cgccagcagt tgcaaattat tgcttacgga aaaaatcgtt atacaacata tacaaatgcg
    21121 cggcactcca ggagaaattt ggtgcgcctt gctgtgcgcc agtcagcggg ttgtaattct
    21181 cctgaattgg gccatcggcg gttaatcctt tggcgtgacg gaagaacgta tccgccagtt
    21241 tcagggcatc atcgcgataa ccgtaacgct ccatcccttt cagaccaaac cagaactgat
    21301 ccacccatac gcgcccacgc cagtagatat cagcgccaaa agccggattg gttaacgccg
    21361 ccgttcccag cgggacaaag gtgttgaact ctttaggatc gagcatcacc ttcaccaccg
    21421 cgtcggcatt ggcctgcgtt gccgcaccgt taaacagcgg cgaccagcct tccggccctt
    21481 taccgcgctc aacaatcggt ttgcccgcgc agccgttcgc cagtggttta tcttcaatac
    21541 gtacgtcata gtagaactgg gtagtcgggt cgaacataca ggtgttgatg tagtccgcga
    21601 gctgctgtgc caactggcga tagcgtttgg cctcttctgg cttaccgagg atggttgcca
    21661 tctccgccag ataatggtta tcgctgtaca tatagctggc ctgatccacc gactcctgca
    21721 atagcgagta gcccagcaac gttccgtcct gactgcggtt ttcggcgaat ttcaccgtcc
    21781 agtcgctacg tttgccgcca ttagcgacat atttatccaa ctgttctttg tcgataaaac
    21841 caaagacggc ggcatcatca cgccccgatt cccacgacgc agcgacctgt gccggaattt
    21901 ccagactgtc gtactggcct ttctccacca cgcgggcgta gttgttcagc ccagactgcg
    21961 tctcttcttt gttgcctttc ttcaccgtaa acagcatctc gccgctctca gtgttgtggg
    22021 ctttgtcgcg ggtcgcgcca tattccggca cgccgttgcc gttgtgatcg cggttacgta
    22081 accaccagtc gtgataggcc accagtttcg ggtacatctc tgccaaccag gctttatcct
    22141 gggtgacgtt gtacacttcc atcaccgacc aggcggcaag gctgggtttg gtattacgtt
    22201 cgttccagtt gccgccatcg ccaccacgct cggggctaag gttccacgct atcaggtcgg
    22261 ggacaaagcc cacatcctgc ggacgcacgc tatcgccagg ctggatctgc caggagaaga
    22321 ccgcgcggat attctctttg gcgatgtccg gattgaaatg cgccatcgca aacgcctgct
    22381 tccaggtatc ccacggccag gtctgattgc cggagaacca gcgcccggtc accgacggtg
    22441 taacggtgtt aaatttcacc gcaccgcccg gtgagcgcca gttaccgttg agcgtttcga
    22501 tcgctttcac cgcgacgcgc gtctgttccg gcgtcgcatc cggattggtt aaccctttct
    22561 tcaggtattc ttcccagcgt tgctgcgagg cggtgagata aaacgccgga cgcgccagaa
    22621 tatcgcggat ctgcatttgc tctttgctaa cttcctgagc ggtcagcaga tgggaatagg
    22681 tggtgtagag cgtggtcgaa ccgttgatat gcgccttact ggtaaagcga ttaccgttga
    22741 tttcagtctg caccggcagg gatttatgca cctgatattc cgattcgccg gaggtcagca
    22801 gatcccaggt ggcgcgcact ttgccaaagg tgactttcag gccatcacgg gtggcgctga
    22861 ttttgcgctg atagtcaggg tattcgccag caatggtttt atcggaaagc ggtttccctt
    22921 ctttcgcttc cagtttttcc agcagttcgc cgtcccacac cagatccagc ggtttattgc
    22981 tggtgatttt ggtttccagt agtgacgtgc gcggcgtggc gaagcgcaga gtcatttcga
    23041 cttgcacatc ttttgctgtc agtttttgca ccagcgcacc gggaatactg tatgcctcca
    23101 gcgtaaagtc gactttcttg ccgtcctgcc agacggtcag gcggtcgaaa ttgctggcca
    23161 taaagttgat gtactcttcc gtcagcagcg caacgcccgg aaagccgccc atggtgttag
    23221 ggccgtctgg caacagatga ccatgccagg ctccgagatc gaaaaacgga ttaaaacgct
    23281 ggtgatcgtc gtaatcgtaa tccttcatgt actgcggcgc gccagtacgg ttaatcacgt
    23341 ttttataatt gtcggcgtta gcggcatggg cggaaaaact tatcagcaga gcgcaggtta
    23401 ctggcgttaa aatagttttt attttcatga aattacagtc cttattacca gtagaaatat
    23461 tgcatcagga agatttggtc gctgggattg tgagaggcat ttttcatgta gaagcggcta
    23521 tcaaaagccg tggcgaaacg tccgccgccg tattcgtacc agataccaaa ctgcatgaaa
    23581 gaggtggttt catcgtcagc gtggtcaggg cgatgtttgg cgtaggtata agcggtggag
    23641 agataaacgc cctttaacgc ttcatacatg gcgctcacca tcatcccact ttcacttccc
    23701 ggtacgtcca gcccgtcggc gcgtccggta tggtgccagg cgcgagcggc aaagttagga
    23761 gttagcaggc ccgtgagata gagctgtcct gtgccgtcgg tgatttccag actgttcatc
    23821 caggtgatgc cttcggcaag gtcatactgg atgtaaccgt tcatcattgc cggataggtg
    23881 tatttgtcgt catagcgatc gtacttgcca aaatgtagcc aggctttgct ttcgtcatga
    23941 tgtccggcag gtgtggcggt gacgctataa cgaaagttgc cgcttaagtt ctgcaccttc
    24001 agcgcggtca taatgtcgcg ggtattggga atgacgtagc ccagatcggg ggtgaagtcg
    24061 ccccaccatt gcaggtcatc cagcgaggaa tcctgacgca gactgagcat gatttcggtg
    24121 ccatcattgg tacgataacc gccatagaaa cggttaattc cgccctcgaa accaccccag
    24181 ctatggtctg gcacccaggc attgccgtcg tggtcggcct gcacggtcca gccttcgccg
    24241 taaatcaggc cgaaccagga gccgtacttc atctccaggc caccttcaat ataggtaccg
    24301 tcgctgtatt tatgtttatt ctcaccctct aaatccatat atccaccaac ccctaattcg
    24361 ccgtaaaaac gaaatgaagg agaagatgtc gaggtaattg caggtgtttt tgtgtcgtca
    24421 tgttctgccg gacgtgcttc ttctcctgcc gcagaaaagg cgtagcaaaa cggcagagca
    24481 agtaatgctc tgcatggtgc agtgattaat ttcattgtgt taatccatga gctaaagaaa
    24541 aagtacagcc ttttatcgtt gtaattataa aaatataaag gcagaaacta ttttccctct
    24601 cctcatccag gaagagggaa aatgcctgct cattttttat tattctgctt aatcaacatt
    24661 gctggctggc gtcgcttcaa tatggcgctc ttcagccgtt aatcccttta tatatttact
    24721 gtatttccac cacgcaaagc cgaggaagat aacaataccg ccgacgttat aaaaaatgat
    24781 ggtcagaata ttcgcgccag tcgggaatgt cgaagcgaca aaccctacgg caaatatcgc
    24841 aatcagcatt gaaacaacga taataccggt gcggcgggag cccatacgga aatcgcgtgg
    24901 caggtgatct aatttggcgc gtaaattcag gtaagccagc atgatgaata acggcggaag
    24961 catggacgct gcggcggtca tattaataat agtattcatc agatcctgca cggtattgga
    25021 accgagcatc gggataatca tcagcgggat gacgatcagg aactggatcc acgctgcgcg
    25081 cgccggaacg ccgttttcgt tcagttcgac ggttttctta ccaaagatgc cttccgggat
    25141 ttcggagaag aaaattttca ccggcgttgc ggtccacatc agcagggaac cgaacatcgc
    25201 ggtaaaggac accagaccga caaagcgatt catcaacgct tccggtagac caaaatacgc
    25261 cgccatgccg tggaatacct gcaccgatcc gccggtaaat ttcaactctt tgctgctgac
    25321 gaagacgtta atcagcaccg aggagacgga atacagtacg ccgataaaaa tcccggcgag
    25381 gatgatcact ttaacgaacg atttcgaacc gcctttgacg tcgttaacgt acacagcgac
    25441 ggactccgcg ccacctgcgg ccataaagat ccaggtggta acgccgagga acgcccagtt
    25501 gaagttcggg atcatcgcgt caacggtgat ggggtcagca ggctgtacgc cgccaaccag
    25561 cgccgtacct gccagtaaaa tgtaggagag cgttaacagc agcatcagcg ttgaagtgac
    25621 ggaggtaatt ggccccaaca ttttcgcccc gttggtggaa acccaggtgg agaaggcgaa
    25681 cagcaccata ctgataatgg tggtggcaac cggcgtcata atatattcgt atccgaggaa
    25741 ggcatacgaa gcataagcaa taacgcgcgg caacagtgag gtgaaaaaga acaggtttac
    25801 gaaccagtag gtataggcag taataaatgc ccaacgtccg cccagcgaac tttttaccca
    25861 cgcgtagaca ccggcttctg agtttttatt taacgaaaca aattctgcga tgatcagaca
    25921 gaagggaata aaataaaaaa tcgtcgcgag gaaaaacatc ggtgccgagg ccagtccaag
    25981 ctcaatatta ttattgataa cgttgttaaa gctgtaaacg gcggcaaaag tcagcgagag
    26041 caagccgaat ttgccgattg tattacgttt ggtatcagac ataacacatc tccgaaaatg
    26101 tgtagggtag cggtggcggc aaactccttt tgccgccgta gttgttattt gttatggaaa
    26161 taaccatctt cgatggtgac tttgagaacc acttttttga ccgcgttatt gcagataaac
    26221 cgatacgctt catggatatc gcaaataacg atttgccctt cgtggacctc aacggtttct
    26281 ccgcagcctt ttaaatattc acggtcagtt tcatcacgat aatattccac tacctgtaat
    26341 gtctctttcg gcgcatattc aattttttgc tgcccttgca ggtagtaatg cacttcaaaa
    26401 tagcgtcgat gcccggtaaa tagcgcatcg gtcgcggagt ctgtctccac gcggtaagtc
    26461 aatgagtcac cgatggagtg ggcgacgcca ggctgaatgt tgtcgatatt ttcaatcgct
    26521 tcaacgcagc gttgccactt cttgccagag gcgtaaatct ggcggaactg ttctaagtta
    26581 tcgatgatcc tcattgctta ttctcgctgt gcaaattcgt ggaaaagaac cctgcgccga
    26641 actcatacga cgccaggctt tgcgcggtag cttctccgcc agaaaccggc agcaacgtaa
    26701 agccgtagct gaagtcacgg aaccagacgc gccaggagtc cagcacctcg ctgccccagg
    26761 agttggagcc gaggccaagc agctggtgat cgaggttcag ggtgatgtca tcactgcgct
    26821 gcagctcgtt acagtgctgg gcagcgtgga tgttttcctg ggtatagtgc caggcgctga
    26881 agttaattgg gcgctgcgga accaccagca aaccgttgcc gtggcggtta gtcagtgccg
    26941 tccagcggac atgctgacgg ttgccgttgt tctgcgggaa gggatagttc tcgaacatgg
    27001 catcgacggt gctgcgccag atatcgatga tgttagcctg ctggctgtcg gcgtagtttt
    27061 cgcccggtcc acgaccgtaa tacgccacct gatcgtattc gccgttaatc cccatggtga
    27121 aaccgatgca cggaatgatg tgcggatagt cgccgtaacg ctcgccggaa agcgccacgt
    27181 taacctggcc atcggcagcg atgcgccaga tgtaggtgca gcgcatcccg aagtcaaaca
    27241 ccggcggggc aataactgtg cggctgatga tcaacacttc accatcgctc tgttctacgg
    27301 caaagtcgcg cagatgttcc tgcatgatct gcaaatgatt cggttgccac agcccttcgt
    27361 actcctgctt gtggttgtcg atcattggct tgaagaagtt gatctttggc tcgcgggtca
    27421 gcagcgactc gccattcacc tgccaggatg tcggtttgcc actcattttt gagaaggtga
    27481 tcgcgaagtt gtagccgcga acggtgcagc tcaaacgatc gtcttccagc gtcagcggac
    27541 gcgcattatt tggtgcgaaa ggcactggtt gcgcggtgtt ttccttcagc gggaactgat
    27601 aagtggcgat agaatgcccg gcttcgctgt agcgggtgcg ggaatctttg gtcaccgtaa
    27661 tgttgaggaa cgcttcgcgg gcgtccagct gcggcagcgt gatctgcaag ggggcttcgc
    27721 tgttcggcgc aacgtcgcgc agtttaatct gctgcgtcgc gagcgtttca ccttcgacgc
    27781 gcacctctgc gtgcagggtg tagtcatcaa gcgtggtaaa ccacagttta ttttcgactt
    27841 tcagctcgcc gcgagtcaga tccagcgcgt ggatttttac cggcgcgata acctgtttgt
    27901 actctttcag gcccggtccc ggcgtctgat cggaatagat caaaccatca agacagaagt
    27961 tatagttgtt gggatagtcg ccgtagtcgc cgccgaattt ataccagacg ttgccgttgt
    28021 catcctgcgc ctggatcccg tggtcgcacc actcccagac ataatgtccc tgaatacaat
    28081 cgtgcttata gaagacgttc tggtactccg tcagcccgcc tggtccgttc cccatcgcat
    28141 gagcatattc acagatgatg cgcggcttcg gatgcgggta ttcaccaaac tcattcatca
    28201 gcggcacgcg ggtgtacatg gtggaaataa tatcgaccac ttcagcatcg cgatcttctt
    28261 cgtaatgcac cagtcgcgtg tcatccagcg ccttcgctgc gtggtacatc gcgcggatgt
    28321 tacagccata gccggattca ttgcccagcg accagatgat gatcgacgga tggtttttct
    28381 gcgcgtgaat atggcgaaca atgcgctcga cgtagacttt ttcccactgc ggatcgtcgg
    28441 taatacggct gatatcgccg acattagcaa agccgtgcga ttcgacgtcg gtttccgcca
    28501 tcacaaacaa gccgtagata tcacacagtt cgtaaaaacg cggatcgttc gggtagtgag
    28561 cggtacgcac ggagttgata ttgtgctgct tcatcaactg gagatctttc tcgacgcgat
    28621 ccattccaac ggcgcggcct ttgcgatgat cgttgtcgtg acggttgacg ccgtgcagca
    28681 tcacataacg gttattgatc cagaacagac cgtcgcgcac tttgatatca cggaagccaa
    28741 cgcgttgtgg caccacttcc agaacgttgc cgttggcgtc tttcagcgtc atgaccagat
    28801 ggtaaagata aggggattct gctgaccatt gctgcggctg ttcgacagta aaagcaaagc
    28861 tggcgctggt cagtttttca attgccaaat gatcaatggc gctgctgtgc accacgcgtt
    28921 cgccatcaaa cagggtatat tccagcgtcg tgacgacagg ggaggcggcg agattttcca
    28981 gcaccacttc gcaggaaagc gtggcatcgc aataggcttc gtcaaagtcg gtacgcacag
    29041 tgaaatcgtt aatatgcgtt aggtgttttc cgaccagata aacatcgcgg aagatccccg
    29101 ctgaccacca catatcctgg tcttccacgt aggtagagtc cgcccactgc atcacgcgca
    29161 cacacaacag gttgtcgccg gttttaacca tcgcgctgat gtcaaactct gcggtcaggc
    29221 gactgccctt gctgaaaccc acatactgac cgttaacata gacttcaaaa taggtttcga
    29281 cgccgtcaaa tttaatcagc gtctgtttac cctgccagcc gtcgctgagg gtgaaaatac
    29341 gttgataggc accggttggg ttatcgctgg ggacaaacgg cacatcgatg gggaacggaa
    29401 aaccttcgtc ggtatattgc agtttgccgt gaccttccat ttgccacatg gcggggacgg
    29461 taatatgccc ccagtcagcc attaactcag aggtgaaggc ttctggtact tgcagcggat
    29521 ggtcaaaaaa gtggaaattc cactgaccgc ttaagggcag aaacaggctg ctggtttcgc
    29581 gggcaaaggt acgcgcttgc gcaacagaat catatgaaaa aaagtacgca cgcggcgcaa
    29641 gtcggttttc gtgggtgagc tgaatgtttt cccagcgatt catagggcct cccggtagag
    29701 agaaatcgga accattcatg gtgatggtag tttgtgtaat tgctggggag tttagtaaaa
    29761 tttttactaa aaagtagcag gtaaatgcat ttactttaac tggatcacga aaataaacgg
    29821 cagcactgtc cggcaaaaac gattgccgga cagtgtgtaa ggggatttaa cgggtcgtgc
    29881 cgcgcagttt taatttgctg ggaacgaaga ctaacagcgg cagcgcgcga ccatcgcggg
    29941 ctttttcata caccaggtta acgccctgac ttcccatcat ctcggaatgg atgcgcacgg
    30001 tggagagcgg cggaaaggta aatcgcgcgg tggggatatc gttaacgctg ataagcgaaa
    30061 tatcctgtgg gatgttcagg cctcgttcat gaattgcccg cagtacgccg atagcaatgg
    30121 aatcggaagc aacaaacagt gccttcggat agtcttcccg cgccagcatt tgttttgcca
    30181 gttcataacc cgacgaactg gaaaaaccgc cgcgccagat atcctcttcg cgtaccactt
    30241 gtttcagtcg gccatattcc gcaaaggcga cctcacgaat atccgccttg ccaggctcat
    30301 cttcaccgcc aataaaacca atacgattaa cgccctggtt gatatagaag tcgatgattt
    30361 ctttactgat gcgtgccaga tcgatatcca ccgcatcgta accgctgccg ggttcgtgaa
    30421 agtcgataaa acagatattg tcggtcaacg cacaggcggc ggcgcgcagg gcgggcgtgg
    30481 gtttgccgac aattaaaata ccggtgacgt ttttaatgtc tggtaatccg ctgtgttcat
    30541 aacagttggt gagctcaatg cccagctttt cgcactgagt ttcaatgccg tggcggatcg
    30601 ccagatagta aggatcgttg atctccagct cctgttggta gctgtagata gccagaatat
    30661 ggtgttggtt gactgcacct gtctggagtt tacgggcact actggtcttg tactccagct
    30721 tttcggcgat ctcgagaatg cgatgtttcg tctcttcttt cacattcaat gtcggatcgt
    30781 catttaagac cctggatact gtcgccaggg atacgccagc ttcgattgcg atgtctttta
    30841 gtgttgccat gtttaccttt tttactttcc ctgatgtgcg cccccattgt agaggaagtg
    30901 cttatcgggt cacctgtttt cagtaaataa agcgcgtttc tttgacgctg taacggtaac
    30961 acagcggctc acgaatgtga tcacgcctgc attctccatt tttagcctac aggattgaga
    31021 aaaacttttg ctatagttta gtaaaatttt acccgaaggg aggaaacaat ggaaaccgtg
    31081 gcttacgctg attttgcacg tctggaaatg cgcgtcggaa agattgtgga agtgaaacgc
    31141 catgaaaacg ccgacaagct gtacatcgta caggttgatg tgggggaaaa aacactgcaa
    31201 accgtgacca gcctggtgcc gtactacagc gaagaagagc tgatggggaa aacggtggtg
    31261 gtcttatgca atctgcaaaa agcgaaaatg cgtggtgaaa cgtcggaatg catgctgttg
    31321 tgtgcggaaa ccgatgacgg cagtgaaagc gtgttgttaa cgccggagcg gatgatgcct
    31381 gcgggcgtac gcgtcgtata aaaagatcgg atggcgacgt cgtatcgcca tccgatttga
    31441 tattacgctt cttcgacact tactcgcatg gccgccagcg ccttacgcgc cgctttgatc
    31501 accagttcac actgttcaat ggtcagtgtc agtggcggtt caatgcggat cgttttggcg
    31561 ttattgagcg ttccggccac cagtacgcgc tggcggaaca tctcgctggc aaagttatag
    31621 ccgatttcgt tatcaacaaa ctcaattgcc atcaacatcc ctttaccacg cgcttcctgt
    31681 accagatcgg gatattcccg cgccagttga cggaaaccgt ccagcaacat atcgcctttt
    31741 tgctcagcct gagccggtaa gttctgctcc agcaacacat tgatggtcgc cagcgccgcc
    31801 gcacaggcca gcgggttgcc gccaaaggtg gtggtatgca ggaatgggtt gtcgaacaga
    31861 actgaaaaca cctcttcagt ggcgatggtc gcgccaatcg gcatcacgcc gccgccgagc
    31921 gctttggcaa ggcagaggat atccggctgt acgttctcat gctcgcaggc gaacatcttg
    31981 cccgtgcgcc ccatgcccgt ttgtacttca tcgaggatca tcagtgcgcc gaactcatcg
    32041 catagcttac gtacggcggt gagatagccc ggcggcggca gaattacgcc accttcaccc
    32101 tgaatcggtt cgaggatcac cgcagccaca tcatcaccgg tttttttgca ctcgttaaga
    32161 gccgtgcgca tggcttcgat attgccaaac ggcacatgac ggaagcccgg cagcagtggc
    32221 ataaacggtt tgcggaaggt cgatttcgcc gtggccgaca gcgcgccaag tgatttaccg
    32281 tggaacgcgc cgctggtggc aataaaagta aacttgccgc gcggtgactg gtaagctttc
    32341 gccagcttca gcgctgcttc aacggactcg gtgccgctat tacagaagaa gctgtatttc
    32401 agtttaccgg gcgttagcgc agcaagggtt ttcgccaaca tcgcccgtaa cggatcgagc
    32461 agctcctggc tgtgcagcgg ttgtttcgca agttgattct gtacggcgga aaccacaact
    32521 ggattacggt gccccacgtt gaaaattcca aaacctccca ggcagtcgat aaactcctgt
    32581 ccctgggtgt cgacaagcgt atttaaacct cccgcttgcc actctacggc tccgtaatcc
    32641 ccgccggcgg taacagattt gcgatactct aaaaaccccg gattgacatg ctctttgaag
    32701 tattcaatca cctctcggtt aagtgctttc atctcctcat gatccagcgt tcgcttttca
    32761 atgagattca gggcgtgggc gctgcacgct aaagccgatg cgctcgaagg taacctgttc
    32821 aaaatatgct ccggaggctc gcgtatcaca tgataccgat ttaagtattg cagggattgc
    32881 gccactccgg ctgcgatcgc gaaaatcggg ataaacacaa attcggttat catttgtgca
    32941 atatttaatg ctatttgtta acatttgttg ttattttgca cggtttttgt cgggtatgga
    33001 tttgatgatt gctgcgcaaa tgcacgtttt cagggcaata attgcctgat ttttgggcaa
    33061 gataattaac gttttcgtat agtaacagag tgaaagtatt ttaaatcaaa gaattagatt
    33121 tgtgctttaa tcgcaaattg cgatctaaat caaattaatc ggttaaagat aaccgcagcg
    33181 gggccgacat aaactctgac aagaagttaa caaccatata acctgcacag gacgcgaaca
    33241 tgtcttctca tccgtatgtc actcagcaaa ataccccgct ggcggacgat accactctga
    33301 tgtccactac cgatctgcaa agctatatca ctcatgctaa tgacactttt gtgcaggtga
    33361 gcggctttac cttgcaagag ttacaagggc agccgcacaa catggtgcgt cacccggata
    33421 tgccaaaagc ggcgtttgcg gatatgtggt tcaccctgaa aaaaggggag ccctggagcg
    33481 gcatcgtgaa aaatcgccgc aaaaatggcg accattattg ggtgcgggcc aatgcggtac
    33541 cgatggtgcg cgagggaaaa atcagtggct atatgtcgat tcgtacccgg gcgacggatg
    33601 aagagattgc ggcggtggag ccgctgtaca aagcgctgaa cgccggacgt accagtaagc
    33661 gtattcataa aggcctggtg gtgcgtaaag gctggctggg taaactgcct tcattaccgc
    33721 ttcgctggcg ggcgcgtgga gtgatgaccc tgatgtttat cttgctggcg gccatgcttt
    33781 ggtttgttgc tgccccggtg gtgacgtatt tcctctgtgt gttagtggta ttgttggcaa
    33841 gcgcttgttt tgaatggcag attgtgcgcc cgatagaaaa tgtcgcccgt caggcactga
    33901 aggtggcgac cggagagcgt aatagtgttg agcacctgaa tcgcagcgat gagctggggc
    33961 tgacattacg cgcggtaggg cagcttggcc tgatgtgccg ttggctaatt aacgatgtct
    34021 caagccaggt gtccagtgtc agaaatggca gtgagacgct ggcgaaaggc accgatgaac
    34081 tgaacgaaca tacccagcag acagttgata acgttcagca aacggtggcg accatgaacc
    34141 aaatggcggc gtcggtgaaa cagaactctg ccacggcgtc ggctgccgat aaactttcta
    34201 tcaccgccag taatgcggca gtgcagggtg gggaggcgat gaccacggtg atcaagacaa
    34261 tggacgatat cgccgacagt acccagcgca ttggcaccat tacttcgctg attaacgata
    34321 ttgcatttca gaccaatatt ctggccctga atgcggcggt ggaagcggcg cgtgccggcg
    34381 aacagggcaa aggttttgca gtggtggcag gggaagtgcg tcatttagcc agccgcagcg
    34441 ctaatgctgc caacgatatt cgcaagctga ttgatgccag tgctgataag gtgcaatccg
    34501 gttcgcagca ggtacacgcc gccggacgga cgatggaaga tattgtggca caggtgaaaa
    34561 acgtcaccca gttgatcgcc cagattagcc attcaacgct ggaacaggcc gatgggcttt
    34621 ccagcctgac ccgtgcagtg gatgagctta acctgatcac ccagaaaaat gccgagctgg
    34681 tggaagagag tgcgcaggtg tcggcgatgg tgaaacaccg cgccagccga ctggaagacg
    34741 cggtgacggt gctgcattaa tcggtatgcc ggatccggcg gttggagcac aatgcctgat
    34801 gcgatgctgg cgcatcttat caggcctgcg gggtgtgtag cgggtgtagg ccggataagg
    34861 cgcgtcaagc gtcgcatccg gcaattgcac cgcgccactg gcggatgcgg cgattaatcc
    34921 agttgcgtaa tatcaaaagc ggcgcggtcg atcaccgcaa tgatcttttt tatttgtgca
    34981 tcactgatat cgctctggtt gacgcgtaaa tccagcaccg ctttaaaatt atccagcgcc
    35041 cgcttcattt gcgggttctg gcgcagcgcc gcgccaacgc aacgcgcttt gatgcgttct
    35101 tcaatcatct ccacctgttc gcggttttct tccagccact gcgcgccttg ttcggtcagc
    35161 gcaatctgct tcttaccacc ttcctcttcg cggatggtaa tcagcgactg ctcctgcaga
    35221 aaatccagcg ttgggtagat gacgcccggg cttggggtgt aattcccctg ggttaggttc
    35281 tcaatcgctt taatcaattc gtaaccgtgg ctgtcatcgc gcgagagaat atccagaatc
    35341 accagacgca attcaccgtg accaaagaaa cgttgccgac gaccgccgcc gcgaccgtgg
    35401 cgaccaccgc agcattgacc gtgttcatgc tggtgaccgt gtccgcagtg ctcgtgttct
    35461 gacttctcac ctttgcagca gccctcatgg cgtggctggc cttcatgttt acaacaccct
    35521 tcgtgatgat ggctcatatc agcctccttt tgcttgatta gatatatcta atttatatct
    35581 gatgtgagca ttactgcaag tacaaaaatg atttttaaac gtggaagcac ctcacatcca
    35641 ggccggataa gacgttcacg ccgcatccgg cagcattgct atggcactga atgccttcac
    35701 atacttcaga tatatcagtt ctacaaatcg cttgcattta tcatgattaa caatcattat
    35761 catttacgaa aattatttag atatatctga ttactatcac gaaggcgata acaatgaata
    35821 actccccccg ctacccgcag cgcgttcgca atgatctgcg cttccgtgaa ctgactgtgt
    35881 tacgcgttga gcgcatcagc gccggttttc agcgcattgt cctcggcggc gaggcgctgg
    35941 acggttttac atcgcgcggc tttgacgatc acagcaaact cttctttcct caacctgacg
    36001 ctcactttgt gccgccaacg gtaacggaag agggcatcgt ctggccggaa ggaccacgcc
    36061 caccgtcgcg tgactatacg ccgctgtatg acgaactacg ccatgaactg gcgatcgatt
    36121 tctttattca cgacggtggg gtcgccagcg gctgggcgat gcaggcgcaa ccgggcgata
    36181 aacttacggt ggcaggtccg cgcggttcgc tggtggtgcc ggaagattac gcgtatcagc
    36241 tgtatgtctg cgatgaatcc ggaatgcccg cactgcgccg ccgcctggaa acgttgagca
    36301 aacttgccgt taaaccgcaa gttagtgcgc tggttagcgt gcgggataac gcctgtcagg
    36361 attatctcgc gcaccttgat ggttttaata tcgaatggct ggcacatgat gagcaggcgg
    36421 tagatgcgcg tctggcgcag atgcaaatcc ctgccgatga ttacttcatc tggataaccg
    36481 gcgaaggtaa agtcgttaag aatttaagcc gccgctttga agcggaacag tatgacccac
    36541 agcgggtacg tgcagcggct tactggcacg caaagtaact gatatataaa aagaaaaagg
    36601 ctgacgattt ctcgtcagcc tttgctatat ctggtggccc ctgctggact tgaaccagcg
    36661 accaagcgat tatgagtcgc ctgctctaac cactgagcta aggggccatg gtagcggatt
    36721 ataaagtaac tccgtgtcgc aatccagcca ttaccgtgcg cctgctgttt ttataaacaa
    36781 tgtattttca atccgttata cttttcctgg tgatgttaga aaggagtaaa tatggttgag
    36841 gatattttgg ctccagggtt acgggtcgtg ttttgcggta tcaaccctgg gctttcatcc
    36901 gccgggactg gttttccctt tgctcatcca gcaaatcgct tctggaaggt gatatatcag
    36961 gccgggttta ccgaccgtca gttgaagccg caggaggcac agcatctgct ggattatcgt
    37021 tgtggcgtca ccaaactggt agaccgtcca acggtgcaag ccaatgaagt ttcaaagcag
    37081 gagctgcacg caggtgggcg taagctgatt gaaaaaattg aagattatca gccgcaggcg
    37141 ttggcgattc tgggcaaaca agcatatgaa cagggattca gccagcgcgg tgcacagtgg
    37201 gggaaacaaa cgctcaccat tggttcgacg cagatttggg tgctgccaaa tcccagcggt
    37261 ttaagtcgcg tttcactaga gaaactggtt gaagcgtatc gcgagctgga ccaggcgctg
    37321 gtagtgcgtg ggcgataaaa aacgccaccg aaaaggtggc gtttgtgcaa agggactagt
    37381 gccgggtgcg gcgtaacgcc tgatccggcc taccgattaa tcgtccagga agctacgcaa
    37441 cacttcagaa cggctcgggt gacgcagttt gcgcagcgcc ttcgcttcga tctgacggat
    37501 acgttcgcgg gtaacgtcga actgtttacc cacttcttcc agcgtgtggt cggtgttcat
    37561 atcgataccg aaacgcatac gcagaacttt cgcttcacgc gcggtcaggc cagccagcac
    37621 gtcgtgcgtt gccgcacgca ggctttcggt ggtcgcagaa tccagcggca gctcgagggt
    37681 ggtatcctcg atgaaatccc ccagatgcga atcttcatca tcaccgatcg gcgtttccat
    37741 ggagattggc tctttggcga tcttcagcac tttgcggatc ttgtcttccg gcatcagcat
    37801 acgttcagcc agttcttccg gcgtcggttc acggcccatc tcttgcagca tctggcgaga
    37861 aatacggttg agtttgttga tagtctcaat catatgcacc ggaatacgga tggtgcgcgc
    37921 ctgatccgcg atagaacggg tgatcgcctg acggatccac caggttgcgt aggtggagaa
    37981 cttgtaacca cggcggtatt cgaatttatc aaccgctttc atcagaccga tgttgccttc
    38041 ctgaatcagg tcaaggaact gcaagccacg gttggtgtat ttcttggcga tagaaataac
    38101 cagacgtaag ttcgcttcaa ccatctcttt cttcgcacgg cgggctttcg cttcaccgat
    38161 ggacatacga cggttgatat ctttaacctg ctcgatggtc aggccggttt cttcttcaat
    38221 ctgctgcagt ttctgcaggg cgcgatgcac ttcttcagag acatcgtgca gtttttccga
    38281 ccacggcttg ttcatcgcaa ttgccgcgtt gaaccaggta tcgctggttt cgttgccggt
    38341 aaacagggta atgaagtttt tcttcggcat tttgcactgc tcaacgcaga gcttcatgat
    38401 cagacgttct tgcgtacgaa cgcggtccat catgacgcgc atgctgttga ccaggtagtc
    38461 aaactgcttc ggcaccaggc ggaactgttt gaatacttca gacagtttca ggatctcttc
    38521 ctgagcggca gcgtgactgc gacctttcgc tttgatggtg tcacgcgtta caacgtactg
    38581 agcgcgtagt tccgcaaatt tttcgcgagc cagttccggg tcgatgctgt tgtcatcatc
    38641 ggcgctgtcg tcatcgccat cttcttcgtc ttcatcttcg tcatcgtcca gatcttcctg
    38701 ggaaagctca gaaccgacgt gagtggcggt aggtgccaga tcttcttctg cgttcgggtc
    38761 aacaaagccg gtgatcagat cggacagacg cgcttcttct gcttcaacac gatcgtactg
    38821 ttccagcaga taggtgatcg cttccggata ttcagcaacg gagcattgaa cctggttgat
    38881 cccgtcttca atacgcttag cgatgtcaat ttcgccttcg cgggtcaaca gttcaacggt
    38941 gcccatttca cgcatgtaca tgcgtaccgg gtcagtcgtg cgcccgattt cagattccac
    39001 gctggaaagc acctgcgcgg cggcttcggc agcatcttcg tccgcggtgt tttcagccag
    39061 catcagatca tcggcatccg gtgcttcttc catcacctga atgcccatgt cgttgatcat
    39121 ttggatgatg tcttcgatct gatctgaatc gacgatatct tccggcagat ggtcattgac
    39181 ctcggcatag gtcagatagc cttgctcctt accacgggtg acaagaagtt tcagctgtga
    39241 ctgcgggttt tgctccataa gacggtatcc acacttattt catgaggttg gtgttgggcg
    39301 attgacccga tgtccttcag ccgttaacgc tgaaatccaa cggttgttta ccgccaacga
    39361 taattacgag ggcgtactta tatatttgcc gctgcctctc agtgcggctg tcgggggctt
    39421 cccgatcgct cttcggcact taagccgtta aatcactttt tcgccagctc ctggtttaat
    39481 gtccagagct ccaggcgttc ttcgttgctt aaaccatgcg tgcgctcacg agcgattaac
    39541 tcttcctggc gcagttcaag cagcgaatca aacatatggt tgagtgagtc ggtgaaggtt
    39601 tgctcagcaa tattcttatc tgctatatcg tcccacatcg acagtttttc aagggtggca
    39661 gcattatttg taccacgata gtgctctaaa agttgcccgg tggtcagacc tggctgggag
    39721 agacaagtgt tgaccagttc tctgaataag ccaagtccag ggagcttatt ttcatccaga
    39781 ttctcaagcg gcgggaccaa cgtcgctaat tctggatttt gcaccagcaa ccctataagt
    39841 atacgcatgg tcgtgcgttt tagctgcgga acagggcgag aaacgccgct ctctgccgct
    39901 tttggcatta atcgttcaag ctggctgtca tcaagtatgc ctaatttgtt gcctaattcc
    39961 tgacgaagat atattcgcag cgtttcgccc ggcacttgcg atatcaatgg cagtgccagc
    40021 gtactcaaac gtgcgcgccc gtcaggggta ctcagatcaa cttgcggcat caggctgtta
    40081 aacagaaatg cggaaagcgg catcgcctgc tccatccgcg cttcaaacgc ttctttacct
    40141 tcttttcgta ccagcgtgtc agggtcttcg ccatccggca aaaacataaa gcgtagctga
    40201 cggccgtctg tcatgtaagg cagcgccgtt tccagcgctc gccatgcggc atcgcggcct
    40261 gcacggtcgc cgtcataaca gcaaatgaca ttgttggtcg cgcggaacaa cagttgtatg
    40321 tgatcggcgg tggttgacgt acctaacgac gcaacggcgt aattaatgcc gtattgcgcc
    40381 agcgccacca cgtccatata gccttcgacc acaagcagac gattgggttc agcgttatcc
    40441 tgctgcgctt cataaagacc gtaaagctgg cggcctttat ggaaaatgtc tgtttccggc
    40501 gagttcaggt atttgggggt atcgttgccc agcacgcgcc cgccaaaacc aatcacccga
    40561 ccgcgtttat cgcgaatggg gaacatcacc cgctcgcgga aacgatcgta actgcgtccc
    40621 tgatcgttag tgaccaacat ccccgcatca atcaatgact ggcgattttc tggattgccg
    40681 ccaaaccgct tcaggacgtt gtcccagccg gggggcgcaa aaccaatcgc aaagcgagcg
    40741 ataacctcgt ggcttaatcc gcgtttttcc agatattggc gcgcagacgt ggcaacaggt
    40801 tgttgtaaag attgttggta aaacgtattc agaccgtcca tcaactgata aagcgtttgc
    40861 ctctgatggc gctcgatctg gctggggccg ctgcctgctt caaatggcac ttcaagattg
    40921 tgcattgctg ccagctcttc gaccgtttca acgaactcga gcttgtcgta gttcatcagg
    40981 aagtcgatcg cgttgccgtg cgcgccacat ccaaagcagt ggtaaaactg tttctcaccg
    41041 ttaacggtga atgacggggt tttctcgttg tggaatggac aacacgcgtg gaaattcttg
    41101 ccctgctttt tcagcttcac acgggcatcg atcagatcga cgatgtcagt gcgtgccagc
    41161 agatcattaa tgaatacgcg tgggattcgt ccagccatag gccccgattt ttagcaattc
    41221 ataaacgaaa ataagccgcg cattcctttc ggaagcacgg ccttacaact acaactcggt
    41281 ctgatcggag agcaacgctc tcggggaatt agtacagacg agtgcggcgt gcgttttcgc
    41341 gagccagttt cttcgcgtga cgtttcactg cagaagcttt agcgcgctta cgttcggtag
    41401 tcggtttttc atagaactca cgacgacgaa cttccgccag aacacctgct ttttcgcagg
    41461 aacgcttgaa gcgacgcaga gctacgtcga acggctcgtt ttcacgtact ttaattaccg
    41521 gcatgtgcct ctcacctttg attaattcgg tttgccgctg gcatcaacgc cagcttattt
    41581 caaaatggtg cggaatttta ctgcaattgc tgctgctttg taaagcaccg cggccttttt
    41641 tgaaagggac ttttataagg gtgaggagta tacacgaggc tttctccagg ggcgaacaaa
    41701 gttttacatc aacccgcatt ggtcctacac tgcgcggtaa taaagcgagg taaaacaagt
    41761 catgcgtgta ctgggtattg aaacttcctg cgatgaaacc ggcatcgcca tttacgacga
    41821 tgaaaaaggt ttgttagcca accaattgta tagtcaggtg aaattgcacg ctgactacgg
    41881 cggcgtcgtg cctgaactgg cctcccgcga tcacgtgcgc aaaaccgtac cgttgatcca
    41941 ggcggcgcta aaggagtctg gtttaacggc aaaagacatt gatgctgtgg cctataccgc
    42001 aggccctgga ttagtcggcg cactgctggt tggcgcaacc gtggggcgtt ctctggcgtt
    42061 tgcctggaac gttccggcaa tcccggtaca ccatatggaa gggcatctgt tagcgccgat
    42121 gctggaagat aacccgccgg aatttccgtt tgtcgcgctg ctggtgtccg gcggtcatac
    42181 gcagttaatc agcgtgactg gcattggtca gtacgagctg ctcggcgagt ctatcgatga
    42241 tgccgccggt gaagcgtttg ataaaaccgc gaagctgctg gggctggatt atcctggcgg
    42301 accgttactg tcgaaaatgg cggctcaggg tactgccggg cgctttgttt tcccgcgtcc
    42361 gatgaccgac cgtccggggc tggatttcag cttctccggt ctgaaaacct tcgcggcaaa
    42421 taccattcgt gacaacggca ccgacgacca gacgcgtgct gatatcgccc gcgcctttga
    42481 agatgcggtg gtcgatacgc tgatgattaa gtgcaagcga gcgttggatc agactggctt
    42541 taagcgactg gtcatggcag gcggcgtgag tgctaaccgt acgttacggg cgaagctggc
    42601 tgaaatgatg aaaaaacgcc gcggcgaagt gttctacgcg cgtccggagt tttgtactga
    42661 taacggcgcg atgatcgcct atgccggaat ggtgcggttt aaagcaggcg cgacggcgga
    42721 tctcggcgtt agcgtgcgtc cgcgctggcc actggcggag ttaccggccg cgtaaaacta
    42781 tcgggtgccg gagagcaatt tccggcaccg tccttactta aagcaacacc acgggcatcc
    42841 acagtaagcc ggtaatcacc agcaatacga ggaatatcag cccaaaaatc gcccccagtc
    42901 gccagtaatc cgccgttggc agataaccac taccgtagta aatcggactg ggtccggtgg
    42961 cgtatggtgt aagaatgctc cccagaccaa ttgccgcgcc aaccatcagg cagaacaccg
    43021 gcagcgggat ttccggcatc gccagcgcgg cggcgatcat catcggtgcg agggcggagg
    43081 tatacgccgt ggcgctggcg aaaaagtagc gcagtagata aaacaccaca atcaatgcca
    43141 ccatcaccat cgtcggcgaa taaccactta agctgcctgc taacagtttg ccaaaccagc
    43201 taataaaacc ggtgttgttg agtccggtag cgagggtgat aagcgaggcc agccagaaga
    43261 aaacgttcca cgcggcttta ttactgacaa tgtcgtccca actgataatg cgcagaagca
    43321 gcatcagtgc caccacgctg taaccgacca tcgcggcatc gatataatca ccgccgaaaa
    43381 tccacagcac cagcgcgcct accatcagcc ccagcatccg tttttcacgc gaacagagcg
    43441 ggcccattgc ctgcagttcc gtctctgccc agcgcggcac ctgatcgcct gacttcagta
    43501 ccggcgggta cagcacataa gccagccagg gaaccagcag caccagcaaa atactgagcg
    43561 gcaacatccc gaggaaccag tcgccccaac tcagcgtggc gtgagatgcg cttttcatca
    43621 gtccaattaa cagcaagttt ggtgccatcg ccgtcaagaa aatggcgctg gtcacgcagt
    43681 cggcaacaat ccccatccac atgatgtacg agccaatgct gcgcgaactg ctgtcgtttg
    43741 gttgtgattg atagagcggt ggcaggttac ggatgatggg atagataatc cccgcaccac
    43801 gcgccgagtt ggacggtgtt acaggtgcga ggatcagctc ggagaacatc accgcatagc
    43861 cgagaaacag cgtgcgatgt cccatctttt tcaccagaat cagcgcaatg cggcgtccca
    43921 gcccggtttt ttcatagcct gtgccaaaca taaaggcggc gaaaatcagc cagataaccg
    43981 aattagaaaa accggaaacc gcccacgaga gggattttgc agtgaattta aagcctggct
    44041 gggcgagctg ttcggggctg aacagcagcc agggagagag tatggcgatg atggatatac
    44101 ccaccatcgc caccacggca cccggcacgg gttcgaggat cagtccaacg atcacgccag
    44161 taaaaacggc aaagtagagc caggtatgac tctccagccc tgcgggaacc ggaattagag
    44221 caataatggc gatgaccgcc agcggcgcaa ggtatcgcca ccattcagtg gaaggtttca
    44281 tcgtgttatg cctgcgaaaa aggagagggg gcgagcctct ccgggagggt tatttgatgt
    44341 aatggacgtg ctcgcagatc tcttccacga tgggatcgcg gcgttcggcg aacagctttt
    44401 tgttttcggc tatcaggttg ttgccgtggg tatcaataga gacaatcagc gggccgaact
    44461 ctttgacccg gcagacccac agtgactccg gcatcccgag ttctgtccag tgcacttctt
    44521 caatctcttc cacctgggtt gccgccagca ccgcgcagcc tgccgggaaa atcacatgta
    44581 gcgccttgaa tttctggcag ccttcttcgg tcagcggccc cattccgcct ttgccaacca
    44641 ccagtttcac gccggtctgc tcgataaatt cacgttcaaa actttccata cgcatactgg
    44701 ttgtcgggcc aacggaaacc atctcccatt tatcgccgtt tttgcgcacg atggggccag
    44761 cgtggaaaat cgctttgccg ttgagatcgt aagggatcgg acgtttcagt tcgatcaagc
    44821 ggcggtgaca aacgtcacgg caggtcacca gcgtaccggt caggtagatc acatcgccga
    44881 cgcgaatatc ttgcagatct tcagctttga tcggggttgt caggatcttt ttcataacgc
    44941 gctccgggtg tgagacagat tttcaaaggt gagatcggca tgaaccagca gcgtgccgcg
    45001 acgatgcgcc cagcagccgg tagagacagc aacgccgatg gttgacggat ggcgggcggc
    45061 agattcgata tgcacgccca tcactgaact gttgccggtc agcccttgtg gaccaatctc
    45121 cagacggttg agtccttctt ccaggcgtag ctccagctct gccgcttttg gattgggatg
    45181 gcggctgcca atcggacgca aaatggcttt acgcgagagt acggcggcgg tttccaccga
    45241 ggtggcgatg cccacgccca ccagtaccgg tggacaggcg tttacggcga gggcggagat
    45301 attttcgaag acgaatttca ccacgccttc gtagccttct gacggcatta acactttcga
    45361 gcggccaggt agcgtgcagc cgccgcctgc catgtaaact tcgatttctg catcgtcatt
    45421 gtcggggatg atgtcccagg tgacccacgg tacgccgcta ccggtatttt tgccggtgtt
    45481 tacttcgtca aaaatttcta ccgcattgtg acgtagtggc gctttgacgg ttgcctcttc
    45541 cacggcttgt ttgagtatgc tttgcagctc gccaagcagt gggaagcggg aaccgacttt
    45601 aacgaagaac ataatctccc cggtgtcctg acaggcagga cgattcaggt caatcgcttt
    45661 ttgcatgttg tcgaacatcg tatggtagat aattttcccc atcgacgacg tttcggcatc
    45721 ctttagctgt tttagtttat ccaccacgtc atcaggcatt cgggtagaaa tcatggcggt
    45781 aaagttagcg acaatctctg tcaacttatt cactgcctgt tgcttattac tttcgctcat
    45841 catggcaact ccagtttttg tatttgtctg gaaaaattca ccgccacaaa ctaccactaa
    45901 aaatgtggtt ttatattttt tgccaccgtg aatatgtaat taacagttcg tgaatcaacg
    45961 cgaaaataag aatgaatatt gcgccagagc agggaatggc aatgttttgc gaaatacact
    46021 gcgcttatca caactgcgga taattaacga tgctgaatag ctggccttta gccaaagact
    46081 tgcaggtact ggtagaaatc gtccacagcg ggagttttag tgctgcagcg gcgacgcttg
    46141 ggcaaacgcc tgcatttgtc accaagcgga tccaaatcct tgaaaatacg ctggcaacaa
    46201 cgctgctgaa ccgctccgct cgcggcgtgg cgctgactga aagtggccaa cgttgttacg
    46261 aacatgcgct ggaaatcctc acccaatatc agcgactggt cgatgacgtc acgcaaatca
    46321 aaacgcgccc ggaggggatg attcgtattg gttgcagttt tggttttggg cgcagccata
    46381 ttgcgccagc cattaccgaa cttatgcgca attatcctga gttacaggtg cattttgaat
    46441 tgttcgatcg gcaaattgat ttagtgcagg ataatattga tctggatatt cgtattaatg
    46501 acgaaattcc tgattattat attgcgcatc tgttaacgaa aaataaaaga atattatgcg
    46561 cagcacctga gtatctgcaa aaatatccgc agccacaatc attacaggaa ttaagtcgtc
    46621 atgactgtct ggtgaccaaa gagcgcgata tgacccacgg aatatgggag ttggggaacg
    46681 gtcaggagaa aaaatcggtg aaggttagcg ggcatctttc ctccaatagc ggcgagatag
    46741 tgttgcaatg ggcgctggag ggcaaaggga ttatgctgcg ttccgagtgg gatgtgttgc
    46801 cgtttctgga gagtggcaaa ctggtgcaag tattgccgga gtatgcacaa agcgccaata
    46861 tctgggctgt ttaccgggag ccgctctatc gcagcatgaa attacgtgtc tgcgtggaat
    46921 ttctggcggc atggtgccag caacggctgg gcaagcccga tgaaggctat caggtcatgt
    46981 agaaccacca gaaatcactc gggatccttt tcgcgctttc ttttgaattt cgtccagatt
    47041 tttgtctcct gacgacgcca cagacgctgg atgttgtcat gatgacgcag caggatcagg
    47101 caagagagca tcgaaaccgg gaaggtgaat tgtggcttaa accaccatac ataaaacgga
    47161 gcaatcagtg cactgacaat cgctcccagc gacgagtatc cgctcaatag cacggtcagt
    47221 aaccaggttc ccgccattac tccggtgaga tcccagccaa tgggtgcgat ggcaccaaaa
    47281 gcggtagcaa cgccttttcc tcctttaaat ccgaagaaaa cgggccagat gtgtccaaga
    47341 caggcggcga tggcaattaa gcctagccag aaggggctga cacctaattc atacgcgccc
    47401 cagacgggca acattccttt cagaacgtcg aaaatcagta ctgctacggc tgctcccttg
    47461 ccaccgatac gtaacacatt ggttgcgcct ggattgccgg agccgctggt tcgcggatcg
    47521 ggcagcccac acaagcggca aaccagaatg gcactggaaa tggagccgca gaggtacgcg
    47581 atgaggatca ttccaggcgc gattgcactc ataagctgtt ccgttttgaa aattcgtgtt
    47641 caacgatgaa tctgtggata atacgcacat ttcgccggaa gtggtatccg gttagccaaa
    47701 aagcaggcag gacgtgatgg atattgtatt tatagagcaa ctttcggtaa tcaccactat
    47761 tggtgtttac gactgggaac agaccatcga acagaagtta gtgttcgata tcgaaatggc
    47821 atgggataac cgtaaagcgg cgaaaagtga tgatgtggcg gattgcctca gttacgctga
    47881 cattgcagaa acggtggtca gccacgtcga gggggcgcgt tttgcgctgg tggaacgcgt
    47941 ggctgaagag gtggcggagc tgctgttagc acgcttcaac tcgccgtggg tgcgtatcaa
    48001 actcagcaag ccaggcgcag tggcgcgggc ggcgaatgtt ggcgtaatca ttgagcgtgg
    48061 caataatctg aaagaaaata attaatttta cagctgttaa accaaacggt tataacctgg
    48121 tcatacgcag tagttcggac aagcggtaca ttttaataat ttaggggttt attgatgagc
    48181 gatatgcact cgctgctgat agcggcaata ttgggtgtgg tcgaaggatt gacagaattt
    48241 ctgccggtat ccagcacggg ccatatgatt attgtcggtc acttgttggg gtttgagggc
    48301 gacacggcga aaacctttga agttgtgatc cagttaggat caattctggc ggtagtagtg
    48361 atgttctggc ggcgtctgtt tggcctgatt ggcatccact ttggccgccc gttgcagcac
    48421 gaaggtgaaa gcaaaggtcg tttaacgctg atccacattt tgctggggat gattccggcg
    48481 gtggtactgg ggctattgtt ccacgacacg attaagtcat tgtttaaccc gataaatgtg
    48541 atgtatgcgc tggtcgttgg cggtttgttg ctgattgccg ccgaatgcct gaagccgaaa
    48601 gagccgcgtg cgccgggtct tgatgatatg acctatcgtc aggcgtttat gattggctgt
    48661 ttccagtgtc tggcgctgtg gccgggtttc tcccgttccg gggccaccat ttcaggtggg
    48721 atgctgatgg gcgtgagccg ttacgctgct tccgagttct cgttcctgct ggcggtaccg
    48781 atgatgatgg gcgcaacggc gctcgatctc tacaaaagct ggggcttcct gacaaccggc
    48841 gatatcccga tgtttgccgt tgggtttatc accgcttttg tggtggcgct gatagcgatt
    48901 aaaaccttcc tgcaattgat taagcgcatt tcgtttatcc cgttcgccat ttatcgcttt
    48961 attgtggcgg ctgcggtgta cgtcgtgttc ttttgattga gaaaaggttc gggagcaggc
    49021 ctggttttct ccctcgctct gtagggagag ggccggggtg ggggtgattg ttcgcaccgg
    49081 tgctggtctg ttcccctcac cctaaccctc tccccgaagg ggcgagggga tggttcgtgt
    49141 taacgtttag ttttatactc agtcaggctt tgggcaacgt tgttccttcc aactggctat
    49201 cgccgcaatc cgccgtcggg tcagctcctc gcgaatctcc acacctttaa atcccgcttc
    49261 aacgaccgct tttgtcggca ctgactgcgc cacttcccag gcttcgcgca accaacggcc
    49321 ttgcgggtag tccgctgatt caaaaccggt tctgccgcgc acgtcagcct cgctggtcag
    49381 cgccagttgc tcgacacgct gcggtttacg ccaggcatcg atggaatcaa acaatttgac
    49441 gatagttttt gggttcagca ttgggaaggt gtggatgaga tcgtgaaact cagccaccag
    49501 tctggctaaa tcgcgaattt catttggcac gcgcagacgc tggcagagtt gttccactaa
    49561 tttcacaccc gccggaccgt gaccatgatg acgcggccaa agttctggcg gcgtcagtcc
    49621 tttaccgaga tcgtggcata aagttgcgaa acggacatcg acctgcggac tcagcatcgc
    49681 cgccattgag agcgtcatta aggtatgaat acccgtgtcg atttccggat gccacctggc
    49741 aggggccgga acgccaaaca gtgcgtcaat ttccgggaat aaaacgcgca gtgcgccaca
    49801 atcgcgcagt acctggaaga acacctgtgg attgcgggtg gtgagggcgc tttccgtctc
    49861 tttccatacc cgttcaggcg tcaggtgttc cagttcaccc gcatgggtca tctcgcgcat
    49921 cagcgtcaga gtttcatcgg caatacgaaa accgaggtgg gcataacgcg cagcaaaacg
    49981 cgccacgcgc agaacgcgta acggatcttc gccaaaagcg ggggaaacat ggcgcaacag
    50041 acgattttgc agatcgccca gaccgttgta cgggtcgata atctcgccgt tatcgtcctg
    50101 ggccagcgca ttaatggtca gatcgcgacg cttaagatca tcttccagcg tgacatccgg
    50161 tgcggcatag caagtaaaac cggtgtaacc ggaaccggat ttccgttcgg tacgtgccag
    50221 cgcatactct tcatgcgttt gcggatgcag aaacacagga aaatcgcggc ctacctgctg
    50281 gtagcccgcg tcgagcatct cctgtggcgt actgccgacc accacccaat ctctgtcttt
    50341 gaccggtagc cctaacaatg catcccgaac agcaccaccg accagataaa tcttcacgcc
    50401 atcatccctt cgtcaaatac acaattccta ataataagac agtgcaacga agaaggcgat
    50461 ttagttcatc cagcgatctt tgcgtttgcg cgttgggatc aggtgtggca gtaccagacc
    50521 gagcagcaag ccaagcccca gcacgccacc gccatacata aaccattgca tgatgatggt
    50581 gcgctgtttg tcatccaact gtacgctggc ggcatcgacc tttttctgcg cgacaatcag
    50641 ctcgtttttc aatttctgat tttcttcttt taatccgttg atcacgctgt cgctctgcgc
    50701 cactttttgc tgcatttctg cggtgcgctg attccaggtg ttatcgatat tggtgagttt
    50761 atcggtcagg gttttgacct gattttccag atctggcaca cgggagcgca ggcttggctc
    50821 agtgctaagt tgtttcaacg ggatccaggc ggtacggcca gagctgtctt tcacctgggc
    50881 ataattggtg ttggcgtcag tttgtaataa ggtcacttcc tcgccggcgt taaccgtgcc
    50941 cacgaggcga taatgatctc ccggaccgct acggacccag gtattcagtt catcagaaac
    51001 atagcgcgtt tcttcagcgt gtgagacggc agtggcgcta agtgcgagta aagttaatcc
    51061 gatcaggcgt aattttggca tcaggctgtc gttattgtca tggaaagtgg aacgatagta
    51121 gtggcatcag tgtcgctacg caaagcattc gacatcaatc ggaatcctct gtgtcaggtc
    51181 ttgccactgc ttcaaacttt tacgcccgtc aaattgcccg ttgcatggca atttggcgca
    51241 aaatactatc tactgacaaa aaagatcgta ttaagttcgc cgttcatcgt cacttatgtg
    51301 acataaccga taagtaaagg ccatggctca ggaaatcgaa ttaaagttta ttgttaatca
    51361 cagtgccgtt gaggcgttgc gtgaccatct caatacgctg ggcggcgagc accatgaccc
    51421 cgtgcagtta ctgaatattt actacgaaac gccggataac tggctgcgtg ggcacgatat
    51481 gggcttacgt attcgtggcg aaaacggtcg ctatgagatg accatgaaag ttgcaggaag
    51541 agtgacaggc ggcttacacc agcgcccgga atataacgtg gcgttgagcg aaccgacgct
    51601 cgacctggcg cagttaccga cggaagtctg gccgaacggc gaattgcccg ccgatctcgc
    51661 ttcccgcgta caaccgctgt tcagcaccga tttttatcgc gaaaaatggc tggtggcggt
    51721 cgatgacagc cgaattgaaa tcgctctcga tcagggggag gtgaaagcgg gggaatttgc
    51781 tgaacctatc tgtgagctgg aactggaact gcttagcggc gacacgcgcg cggtgctgaa
    51841 actggcgaac caactggtat cgcaaaccgg attacgccag ggcagcctga gcaaagcggc
    51901 gcgtggctat catctggcgc agggcaatcc ggcgcgtgaa atcaaaccga ccaccatttt
    51961 gcatgttgcg gcaaaagccg atgtggaaca ggggctggaa gcggcgctcg agctggcgtt
    52021 agcgcaatgg cagtatcatg aagaactgtg ggtacgcggc aacgatgcgg cgaaagagca
    52081 ggtgctggca gccattggcc ttgttcgcca tgcactgatg ctgttcggtg gcattgtgcc
    52141 gcgtaaagcg agcactcact tacgtgattt gctgactcaa tgcgaagcga ccatcgcttc
    52201 tgcggtttct gccgtgacgg cggtctactc taccgaaacg gcaatggcaa agctggcgtt
    52261 gaccgaatgg ttggtaagca aagcctggca gccgttttta gatgccaaag cgcagagtaa
    52321 aatgagcgat tccttcaaac gctttgccga tatccatctt tcccgccatg ccgctgaact
    52381 gaaaagcgtt ttctgccagc cgttgggcga tcgctaccgt gaccagttgc cacgtctgac
    52441 gcgtgatatt gactcaatac tgttgctggc gggttactat gatcctgtcg tcgcgcaagc
    52501 ctggctggag aactggcagg ggctgcgtca cgctattgcg accgggcaac gcattgaaat
    52561 tgaacatttc cgtaatgagg caaacaatca ggaaccgttc tggttgcaca gcggaaaacg
    52621 ttaatcaggc aaggataaaa tcgcttatga agccgctctc ttcaccgtta cagcagtact
    52681 ggcagaccgt tgttgagcgg ctgccagagc ctttagccga gaaatcactt agcgcacagg
    52741 cgaagtcagt acttactttc agtgattttg tgcaggacag cgtgattgcg catccagagt
    52801 ggctgacgga actggaaagc caatcgccgc aggctgatga atggcagcat tacgcggcat
    52861 ggttgcagga ggcgctcagc aatgtgagtg acgaagccgg gttaatgcgc gagctgcggc
    52921 tattccggcg gcgcattatg gtgcgcatcg cctgggcgca aacgctggct ttggttactg
    52981 aagagagcat attgcagcag ctcagccatc tggcggagac gctgattgtc gccgcgcgtg
    53041 actggctgta tgacgcttgc tgccgcgaat ggggaacgcc gtgcaatgcg cagggcgaag
    53101 cgcaaccgct gctgatttta ggcatgggta agctgggcgg tggggaactg aatttctcct
    53161 cagatatcga tctgattttt gcctggccgg aacatggttg tacgcagggc ggacgccggg
    53221 aactggataa cgcgcagttt tttacccgca tggggcagcg gctgattaaa gtgttggatc
    53281 aaccaacgca ggatggcttc gtctatcgcg tggatatgcg gctgcgtccg tttggcgaaa
    53341 gtggcccgct ggtgctgagc tttgccgcgt tggaagatta ttaccaggag caggggcgcg
    53401 actgggagcg ttacgcgatg gtcaaggcgc ggattatggg cgatagcgaa ggcgtctatg
    53461 ctaacgagtt gcgtgcgatg ctgcgcccgt ttgttttccg tcgttacatc gatttcagcg
    53521 tgattcagtc gctgcgcaac atgaaaggga tgattgcccg tgaagtgcgt cgacgtggtt
    53581 tgaccgacaa tatcaaactc ggcgcaggcg gcattcgcga aattgaattt atcgttcagg
    53641 tgttccagct cattcgcggc ggacgcgaac cgtcgctgca atcgcgctct ttactgccaa
    53701 cgctcagcgc cattgccgag ctgcatctgc tttctgaaaa cgatgctgaa caattgcgag
    53761 tggcgtatct gttcctgcgg cgtctggaaa acctgctgca aagcattaac gacgaacaaa
    53821 cccagacgct tccttctgat gagcttaatc gtgcgcggct ggcgtgggcg atggactttg
    53881 ctgactggcc gcaactgacc ggggcgctga ccgcacatat gaccaatgtg cgccgggtgt
    53941 ttaatgaatt gattggcgac gatgaaagtg aaactcagga agagtcgctg tcggaacagt
    54001 ggcgtgagct gtggcaggat gcgttgcagg aagatgacac tacgccagtg ctggcgcatc
    54061 ttagcgagga tgatcgcaaa caggtgctaa cgctgattgc cgatttccgc aaagagctgg
    54121 ataagcgcac catcgggccg cgaggacgtc aggtgctcga ccatctgatg ccgcatctgc
    54181 taagtgatgt ctgtgcgcgt gaagacgctg ccgttacgct gtcgcgcatt accgccttgc
    54241 tggtggggat tgttacccgc accacctatt tagaattgct cagtgaattc cccgcggcgc
    54301 ttaaacattt gatttctctg tgtgccgcgt cgccgatgat tgccagccag ctggcgcgtt
    54361 atccattatt gctggatgaa ttgctcgatc caaacaccct ttaccagccg acggcgaccg
    54421 atgcctaccg cgatgagttg cgccagtatt tgctgcgcgt gccggaagat gacgaagagc
    54481 aacagcttga ggcgctgcgt cagttcaaac aggcgcagct gttacgcatc gccgcagcgg
    54541 atatcgccgg tacgctaccg gtgatgaaag tgagcgatca cttaacctgg ctggcggaag
    54601 ccatgataga tgccgtcgtt cagcaggcgt gggttcaaat ggttgcccgc tacggtaagc
    54661 cgaatcacct gaacgaacgc gaagggcgtg gttttgcggt ggtcggctac ggcaagctgg
    54721 gcggctggga gttaggctac agttccgatc ttgaccttat cttcctccat gattgcccaa
    54781 tggatgcgat gactgacggt gagcgggaaa tcgacgggcg gcagttttat ctgcgtctgg
    54841 cgcaacgcat tatgcatctg ttcagtacgc gtacctcttc cggcattttg tatgaagtgg
    54901 atgctcgact gcgtccgtcc ggggcggcgg gaatgctggt gacatccgca gaagcatttg
    54961 ccgattatca gaaaaacgag gcctggacgt gggaacatca ggcgctggtg cgtgcgcgtg
    55021 tagtgtacgg cgatccgcag ctcaccgcgc actttgacgc agtgcgtcgc gagattatga
    55081 cgctgccgcg tgaaggtaaa actctgcaaa cggaagtgcg ggaaatgcgc gagaaaatgc
    55141 gcgctcatct cggcaataaa catcgcgatc gctttgatat caaagctgat gaagggggaa
    55201 ttaccgatat cgaatttatt acccaatatc tggtgttgcg ctacgctcat gaaaaaccga
    55261 agttaacgcg ctggtcagac aacgtgcgta ttctggaact actggcgcaa aacgacatta
    55321 tggaagagca ggaagcgatg gcgctgaccc gtgcttacac tacgcttcgc gatgaacttc
    55381 atcatctggc attacaggaa ttgccgggcc atgtgtcgga ggattgcttc accgcagagc
    55441 gtgaactggt gcgggcaagc tggcagaagt ggctggtgga agaatgaagt atggtattat
    55501 cgcgcgcaaa ttttgaatct ctcaggagac aggaatgaaa gtaacgctgc cagagtttga
    55561 acgtgcagga gtgatggtgg ttggtgatgt gatgctggat cgttactggt acggccccac
    55621 cagtcgtatc tcgccggaag cgccggtgcc cgtggttaaa gtgaatacca tcgaagaacg
    55681 tccgggcggc gcggctaacg tggcgatgaa tatcgcttct ctcggtgcta atgcacgcct
    55741 ggtcgggttg acgggcattg acgatgcagc gcgcgcgctg agtaaatctc tggccgacgt
    55801 caacgtcaaa tgcgacttcg tttctgtacc gacgcatccg accattacca aattacgggt
    55861 actttcccgc aaccaacagc tgatccgtct ggattttgaa gaaggtttcg aaggtgttga
    55921 tccgcagccg ctgcacgagc ggattaatca ggcgctgagt tcgattggcg cgctggtgct
    55981 ttctgactac gccaaaggtg cgctggcaag cgtacagcag atgatccaac tggcgcgtaa
    56041 agcgggtgtt ccggtgctga ttgatccaaa aggtaccgat tttgagcgct accgcggcgc
    56101 tacgctgtta acgccgaatc tctcggaatt tgaagctgtt gtcggtaaat gtaagaccga
    56161 agaagagatt gttgagcgcg gcatgaaact gattgccgat tacgaactct cggctctgtt
    56221 agtgacccgt tccgaacagg gtatgtcgct gctgcaaccg ggtaaagcgc cgctgcatat
    56281 gccaacccaa gcgcaggaag tgtatgacgt taccggtgcg ggcgacacgg tgattggcgt
    56341 cctggcggca acgctggcag cgggtaattc gctggaagaa gcctgcttct ttgccaatgc
    56401 ggcggctggc gtggtggtcg gcaaactggg aacctccacg gtttcgccga tcgagctgga
    56461 aaatgctgta cgtggacgtg cagatacagg ctttggcgtg atgaccgaag aggaactgaa
    56521 gctggccgta gcggcagcgc gtaaacgtgg tgaaaaagtg gtgatgacca acggtgtctt
    56581 tgacatcctg cacgccgggc acgtctctta tctggcaaat gcccgcaagc tgggtgaccg
    56641 cttgattgtt gccgtcaaca gcgatgcctc caccaaacgg ctgaaagggg attcccgccc
    56701 ggtaaaccca ctcgaacagc gtatgattgt gctgggcgca ctggaagcgg tcgactgggt
    56761 agtgtcgttt gaagaggaca cgccgcagcg cttgatcgcc gggatcttgc cagatctgct
    56821 ggtgaaaggc ggcgactata aaccagaaga gattgccggg agtaaagaag tctgggccaa
    56881 cggtggcgaa gtgttggtgc tcaactttga agacggttgc tcgacgacca acatcatcaa
    56941 gaagatccaa caggataaaa aaggctaacc ggaaagcggt tcacagatct cgcttcgtac
    57001 atggcaggcc tattgacgct gttgtttttt caacctagag taaaggaaca agggtaaggg
    57061 aggatttctc ccccctctga tgagttgtta gtaagtcggg aaacttaaca gtaacaacac
    57121 aaccagtatg atgacgagct tcatcataac cctttcctta tacaaggccc cttcttcggg
    57181 aggggctttc ccgtttcagc cccttgctgc cccccgattg ttgatgagcg ccggaccccg
    57241 cgcaatgctt tcccagaggc aattttgcct tccccgagcg gtcacgcaaa acgctgcaac
    57301 gtcctgagca tttgcacctt ttagcggaac gcagatataa aaaatccccg gctttttggg
    57361 ccagggatat gtgttaatga aaccttcttg acgctgattt tttttcaacc taaagtaaag
    57421 gaacaagggt gagggaggat ttctcccccc tctgattggc tgttaataag ctgcgaaact
    57481 tacgagtaac aacacaatca gtatgatgac gagcttcatc ataacccttt ccttctgtaa
    57541 ggcccccttc ttcgggaggg gctttcccgt ttcagccccc tgctgactcc ccgattgttg
    57601 atgagcgcca gaccccacgc aatgctttct ctgatgcagt ttttccttcc ccgagccgtc
    57661 acgcaaaatg ctgcaacaac ctgatcattt gcacttttta gcggaacgca gatataaaaa
    57721 atccccggct ttttgggcca gggattattc ctggaagagg gtttactctg ctttttcttc
    57781 gacgggagtt gttgaggtta agggtgaagt caatgccgcc agtgagccgc ctgaaacgcc
    57841 aatttcattg agcaaggagt caatcagcgg tgcctgtgtg cggtaagaga gagcggctga
    57901 taatgcttgt tccgccaggt ttccgccccc cacattaccc gtgtttgcat cacccgcagc
    57961 gccgccacga ttcagaccat cgacctgaat aatcttgata ccgtcgattg acttcatcgg
    58021 ctcaacggat ttctctatta ccgcaggcag cgcctgcaac aaggccagtt tgaatttaag
    58081 gctggtttgt tcatcagaaa gtacgttgat agcatcgttc agcgcacgtt gtgcttctgc
    58141 ttccgccaga ccctttttac gtgtagcttc ggctaactca acgatagccg ccgcctgcat
    58201 ctctgcggct tctttttctg ctttcgcccg cacggtcagt tcaaccgctt tggtttctgc
    58261 atcctgcgcg gcagcgatta gggcaacttg tttagcacga tcggcttcgg cagtctggcg
    58321 agtggtttct acgttttgtt gggcgcttac cgcttctgca agtgcgagat tagcacgcgc
    58381 ttctgcctgg gactgttgtt ccgatttggc ggcaatagcg atcgatttcg tctggttagc
    58441 gatttcggtg acctgctgct gttcgatctc tttaatgcga acttcacgtt cagcttcaac
    58501 ctttcttgag cggacggcct gttcgcggtc gatttctgtt tcctgaatct gtcgttcagc
    58561 cagaattcgt gtctgctctg cttcacgacg acgttcagct tcaaaagccg caatacgtgc
    58621 attctgttcg gcagtacggg ttttaacctg ctgctcctgc tcaagcgtca taaacgcttc
    58681 ttgctgttca atctccagct tgcgcgatag cgcatcgcga tttttttcac gcaccgcaac
    58741 ttctacatcc tgttcaactt cgttacgttc gcggcgacgg cgctctgttt cctgagtcag
    58801 tttggttaaa ccttcggcgt caaaggcatt gttcggattg aaatgttctt tcgaggtctg
    58861 gttaaagttg gtaagtgaaa cgctctccag ttccagaccg tttttcgaca ggtcttctgc
    58921 cactgtattt tgcaccccct gcacaaagtt ctcgcgggta tcctgtaact catgcatggt
    58981 catttgcgca gctgttgcac ggagggcatc gacaaattta tcttcaacca acatacgtaa
    59041 gtcttcaggc gacagggtgc gttgccccag cgtctgggca gcggtggcaa tcccttctac
    59101 tgaaggtttt acccgcacaa agaaagcgac tactacatcg acgcgcatac gatctttcgt
    59161 aatcaggcta tcaatggttg agcggctgac ttccagcttc agagtattca tattgatggg
    59221 gattatttca tgaaagatcg gcatcacgat tgcgccaccg ctcattacca ctttttgccc
    59281 acctaaacca gtacgaacaa aagcttgctc tgccgaagcg cgacgataga gcctggcgaa
    59341 aataattcca ataataaaca gaatgcatac ggcaataatt gcggtaaaca tccaggaggg
    59401 cacagaatta acaatatcat ccattattaa atttcctttt gattaataaa ttacaatatt
    59461 tggggccagg gattattttc cgccaaatat cgcgttgcag aaagtcggca aataattaac
    59521 actttgtctc ctttagtgaa aatttttcct tcttcaggct ccagtagtaa ataatgtatt
    59581 tggccaaatt gatcggtgag ttttccttcg cagggattac ctgaagtggc ttgatgaccg
    59641 gtaattaacg ccatgctacc aatatattct tcttctgtaa tagctgaact atggtcgcgt
    59701 ggaatccagg gcgcaactat tttaccggta taatgcaccg caataatcgt aaacagtaaa
    59761 ctgacaggaa ccacgaacag gttcgacagt ggtgattgcc agaccatgat gcaggcatgc
    59821 tgcaacagga tgccaataag accaaaaaaa ccagccagta agcagagaac gacgagagct
    59881 ggcaatcttc caatattgag ataatgaagt gcctggctaa tatgacctgt ggttatagaa
    59941 tcataatggt caagatgtgc atcaagagca ccggagagca tgtgaccgca gataagcgca
    60001 aaaatttcta acaggccgat caacagtaca aaggaaatag cgaaaagata aggggtgtta
    60061 tagtcggcga ataaaatcat atatcactcc aatgtccatt tagtgacgca atatttactt
    60121 tgtaatagtt tccttgctta catttatctg tgttaataat aacacaggtt agagaagttc
    60181 tggaagagaa agtcttttaa tatggttttt tatttttcac taaaaagtgt gatcggggac
    60241 aatatattta cgcacgttat gtttaaaggc actacactga ttggggaata ctgaaatcag
    60301 aaaaagcata tggccttaaa aggtatgcga taaccggagg atgtgcttat ggatcatagt
    60361 cttaattctt taaataattt cgatttcctg gcgcgtagtt ttgccagaat gcacgcagaa
    60421 ggtcgcccgg tcgatattct tgccgttact ggtaacatgg atgaagaaca tagaacctgg
    60481 ttttgcgcac gttatgcctg gtattgtcaa cagatgatgc aggcaagaga gctggagtta
    60541 gagcactgat ataacgggcc tgatggcccg ttttagtgtt tgtattagat gctagttata
    60601 ggtgattttg aggatgacgt ctttactaaa cggtccctca acaacagtct ctgccggatt
    60661 cgcactaagt tctgccctga atggtgcggt gaccgaaggt gcactagacg atgaaaaaga
    60721 agcaaattgt gagaagcggt taaattccgt tgctgttcca tctttatgaa atatcttcaa
    60781 tagcagtcca ttacccatat ccagatggct ataatcactc aaaatatccg tagtgaaaaa
    60841 gctccctaaa atattgaatt gctcagtaca ggccgcacca ggatcttttg tcatgactac
    60901 actaaacgtc tcactaacgc tggtattttt aattgttcgg gaatttattt taccaaagtc
    60961 aacaacgcca tcagctggtt ccagtgcgac attaacaaag cagtcaagga catgaatatt
    61021 atttaatcca cgaatcctga aggtcaaatt tttgtctact tctatagctc ctgcgccact
    61081 cataccttta aactctagag cgatatattc atcaggtaac accaggtttt tattaactct
    61141 attggcattt tttgctaatt taatatagag ttgtacgcga gctggaaagg ttactgataa
    61201 ttgaggctca ggacctccac tacagacagc ggggttttta tagtgattat taaaggtacc
    61261 cgctcctttt atatcaatgc attctggtgc tgcgatagca ttaggggcag tcgaatcata
    61321 atcaactcca ttgtatgtta cgccaaaaat ataggagttc tgattataaa agtcctgacc
    61381 gcctggtaaa aacatcatta tattagtcca ggctgatggg tattcttctc caggtgatgg
    61441 ggcaggtaat gcattattac agaagacatt cataaaatac tcactgcttt gccagatctt
    61501 atcacctttt ttaccattac tggggataga aattcttggt acgtaaccaa tgactacggt
    61561 atttccccct tcatgttcag catagcagtc cattgcccat acaggtaatg cactaaaacc
    61621 tataataaat ataattacaa ttaataagta gcgcatatta tttatctcgt ttggctacgg
    61681 aaacattaca agagttatta accgtcgggc agtttatttc ataaaaactt aatccaccaa
    61741 aatcattgat ataacccacc tgaaaagttg acggaacatt tttaaactgc gtatttgcat
    61801 agctaaaagg ggttaccatt aagctttgcg tttgtggtaa catcgttacc ccatttgttc
    61861 cgatataacc cagcgtaacg tgataaggca tcttattgtt aaagcggatc gaaccgtcat
    61921 ttctacgaat gatttcaact ttttcgtaag tcattacccc atcgtcttct aattcaatgg
    61981 cttttggccg ccagaatagt ttcaatgcgt gctgcatagt gacttgcatc acattttttt
    62041 tatctgtttt gggcggtatt tctcgcacgt taaaatagaa gagcgtttct ctgtctttag
    62101 gaagttgagc aattttttcc tgagttatca ttcttatttg aatttgctca ctgggattta
    62161 aacgtaccat agggggaacc gtgacaataa agtcacgtga tttattgcct ttcgtatctt
    62221 ctatccatgt ttgcgccaga tagggtagat ttttgctttg attagtaagt tttaatgctt
    62281 cccctttatc tgactcattc attatgatac gggtacggtc cgggatgatg gcaccccagg
    62341 caatgctgct catgcaggcg agtaatactc ctgctgcaat gagattcttt gtgtttaagt
    62401 agcgcattag tttcatcctg aattaatttt ggctaataca cggtaaaata accgttccgg
    62461 tggttaagtt gctgctattg ggtggttgaa taaaacagga tttatcaccc cagcgtaaag
    62521 taagtttgct gtcatcctga atgccgttga ggtatacaaa gccgccatca gcaaccagtc
    62581 ctaattcttt atggctggtt ttatctttta cgctaatccc cagtggtggg tgactaccat
    62641 ctgccaggcg aataaccccc atgatttgat agcccttgcg ggtatcaagt ttggcgtagc
    62701 caatagcacc ttcggttaag gtggtggtga taaccgagtt ttcgatatcc acattttctg
    62761 gcagatttcg ggtatcaaca cttaatgatg ttgttatgta actgctgact gatggaataa
    62821 ctccgatgcc ataccgatta gttaccgcgc gtttattgtt caacggaata tcttcagtgc
    62881 cgtctgcgtc gatcataaaa cgcgagtcag cactaccgct atagtcgtgg aaagcggcac
    62941 cgtggcgagt cgcagtgaat gaaccattcc aactggcatt cagagaataa taactgtctc
    63001 gctgtgatgt accggagagg tagagtcgac cgttctcggt attatgctga taactggcgc
    63061 gtagtgacgc tttcatatct ttgaattcat cattgtcgcc tgaagcagaa acgctccagg
    63121 aattatttcg atcggaagag tcataccacg aagcagtatg cgaaatctca ttatcctgat
    63181 ttcgttgcat accatagctc aatgttctac tagttcccca gggaatcgaa atatttaggt
    63241 acagttgatc ctggttgtct tcttcccagt ttattcggct aaatgttaga gaagtggaga
    63301 cgttttttaa tggcccgata tcaaaatcgc ggctaagtga taatgaataa ttcacattac
    63361 tgctggcgtc ccagtaagta ttacgagcca aacttacgta tgtatttaac cttaatgatt
    63421 caagatactg gttaaacgtg acaatataac tctctttttc attctgataa ttcgtgtaat
    63481 ggttagtgtc attgatatat tcattcattg tcacaaagtt tttatcagag aaacggtaac
    63541 cagcgaaagt gagctggcta ccggtagatt caaaacgttt tgaatagtta gcgcggtagc
    63601 tataacccgt ttctttatcc tgattatgca actgagcatc agatcgtgtg acatcaaaag
    63661 ataatgaacc taatgagtta aggttaaaac caacgccggc agccagagat tgataatcac
    63721 ggtttgttaa aactgaacca ccatacaggg atacattgtt cagccaaccc catgagaatt
    63781 caccagtcca gaagaagggt tgttgtaagg aatcaccacc aacgctggtc ggtttaccca
    63841 tagcagtggt gtagcgaatc tgccctttac gcgtcagata aggaatacta ttagatgcaa
    63901 cttgccattg cgtaacgcgt ccgtcctctt cttcaacctt gacgtcaagt tgcccctgta
    63961 atgtattgaa taaattggta atagcaaatg ggcctggagg aacattttct tgataaataa
    64021 tacggttgtt ctgtgagaca gtgacctttg cattcgtttg tgcgacaccc gtgatttgcg
    64081 gtgcgtaacc acgtaggtct ggcggtaaca tattctcatc gcttttcaac gaaatgccag
    64141 aaaaatggaa agagtcgaaa atagaggatt cagtatcgta ttgacctata gttagttttg
    64201 cattcattgc tgggattggg cgaaacaaat aaatacgcgg aaaatccagg ttggtcgcct
    64261 ggcttttgcc attgttaaat gactgatcgt actggtaatc agtacgcagg cgccaggccc
    64321 caagattaac cccagcctgc ccataggaac ttatattttg cgaattatcg ccctgatgtg
    64381 gtgcataatg agaggcatat aaattgtagt caagaaatgc cccagcaata ccatgattcc
    64441 aaagttcagg aggcgtccag tttgcatctt tgtattttaa ccatgcctga ggtgcagata
    64501 tggataattg cattttccct ttatcgagat aagttgtaat ttgtttttct ttttcgatag
    64561 ggtaacaacc atcgatcagg ttttgctgag ttttttcaat aaattcatca gtaaatccta
    64621 ataatgttaa ttgctctggt gtcacgcaaa ctgcagtttg gttatcaatt aatacccatt
    64681 ggaggtcaag gtggattggc gtcctcttat tattaatcag agtgcttagt gaatatttgc
    64741 cgacgggtaa ttggccatca gtttcaaatt gggaaaggtt aacgttttca cgatcttcgg
    64801 cttcgattaa atctttgttg aattcaacgg cataagctga cgcacaacca atgatgataa
    64861 cggataatga acaataaata tttttaatca attcgcttat tgtggttaat tttaattttt
    64921 tatacatctg atccacttat cattaatccg ttaatgatgt ggccgggcga acccggccaa
    64981 atgcgattac tcgtaagcaa tcttgtagtc agcctgagcg taaacgttgc ccggggtggc
    65041 atctttgctt ggggattcca tacgagcttt gaaattcagt tcctgatagc tgttggtatt
    65101 gttgaacgta attactaccg gagtacctaa agttacttcg ccgctctggc tgtccagaat
    65161 acgtacgcca acgccagtgg cgccgccgat ttcagtttct ttggtatttt tcagaagatc
    65221 agactgaccc gtcatggtat ttgctgtagt gaaagtaacc ttcgcttttg aataagtagt
    65281 tccaccctga ctcagcatgc agtcctgcag gtgaatagtg aaaggttcag ccaaagattt
    65341 ctgatcgctt ttcagtacgg tatctgctac ttcacccaga tttacagtta aatcttcgtc
    65401 acctggttta atagaacatg gagcagagat aacttcacct ttaaatttaa caataccgtg
    65461 accttcatca gcaaacacgt tattggaaag aatcattgct acgccagcaa caagaagtga
    65521 ctttttaaaa gcggaca
//
LOCUS       DAPOAV010000015        65393 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.015, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000015 DAPOAV010000000
VERSION     DAPOAV010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 65393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65393
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.015"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            427..882
                     /gene="csgB"
                     /locus_tag="RN951_001159"
     CDS             427..882
                     /gene="csgB"
                     /locus_tag="RN951_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curlin minor subunit CsgB"
                     /protein_id="HDX2526190.1"
                     /translation="MKNKLLFMMLTILGAPGIAAAAGYDLANSEYNFAVNELSKSSFN
                     QAAIIGQAGTNNSAQLRQGGSKLLAVVAQEGSSNRAKIDQTGDYNLAYIDQAGSANDA
                     SISQGAYGNTAMIIQKGSGNKANITQYGTQKTAIVVQRQSQMAIRVTQR"
     gene            923..1378
                     /gene="csgA"
                     /locus_tag="RN951_001160"
     CDS             923..1378
                     /gene="csgA"
                     /locus_tag="RN951_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curlin major subunit CsgA"
                     /protein_id="HDX2526191.1"
                     /translation="MKLLKVAAIAAIVFSGSALAGVVPQYGGGGNHGGGGNNSGPNSE
                     LNIYQYGGGNSALALQTDARNSDLTITQHGGGNGADVGQGSDDSSIDLTQRGFGNSAT
                     LDQWNGKNSEMTVKQFGGGNGAAVDQTASNSSVNVTQVGFGNNATAHQY"
     gene            1437..1769
                     /gene="csgC"
                     /locus_tag="RN951_001161"
     CDS             1437..1769
                     /gene="csgC"
                     /locus_tag="RN951_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli assembly protein CsgC"
                     /protein_id="HDX2526192.1"
                     /translation="MNTLLLLAALSSQITFNTTQQGDVYTIIPEVTLTQSCLCRVQIL
                     SLREGSSGQSQTKQEKTLSLPANQPIALTKLSLNISPDDRVKIVVTVSDGQSLHLSQQ
                     WPPSSEKS"
     gene            1890..2201
                     /locus_tag="RN951_001162"
     CDS             1890..2201
                     /locus_tag="RN951_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDX2526193.1"
                     /translation="MFRPFLNSLMLGSLFFPFIAIAGSTVQGGVIHFYGQIVEPACDV
                     STQSSPVEMNCPQNGSIPGKTYSSKALMSGNVKNAQIASVKVQYLDKQKKLAVMNIEY
                     N"
     gene            2296..2829
                     /gene="ymdB"
                     /locus_tag="RN951_001163"
     CDS             2296..2829
                     /gene="ymdB"
                     /locus_tag="RN951_001163"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyl-ADP-ribose deacetylase"
                     /protein_id="HDX2526194.1"
                     /translation="MKTRIHVVQGDITKLAVDVIVNAANPSLMGGGGVDGAIHRAAGP
                     ALLDACLKVRQQQGDCPTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYL
                     NSLRLVAANSYTSVAFPAISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYD
                     EENAHLYERLLTQQGDE"
     gene            2771..4252
                     /gene="clsC"
                     /locus_tag="RN951_001164"
     CDS             2771..4252
                     /gene="clsC"
                     /locus_tag="RN951_001164"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706957.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase ClsC"
                     /protein_id="HDX2526195.1"
                     /translation="MMKKTPTSTKDSLPNKEMNDLPRLASAVLPLCSQHPGQCGLFPL
                     EKSLDAFAARYRLAEMAEHTLDVQYYIWQDDMSGRLLFSALLAAAKRGVRVRLLLDDN
                     NTPGLDDILRLLDSHPRIEVRLFNPFSFRLLRPLGYITDFSRLNRRMHNKSFTVDGVV
                     TLVGGRNIGDAYFGAGEEPLFSDLDVMAIGPVVEDVADDFARYWYCKSVSPLQQVLDV
                     PEGEMADRIELPASWHNDAMTHRYLRKMESSPFINHLVDGTLPLIWAKTRLLSDDPAK
                     GEGKAKRHSLLPQRLFDIMGSPSERIDIISSYFVPTRAGVAQLLRMVRKGVKIAILTN
                     SLAANDVAVVHAGYARWRKKLLRYGVELYELKPTREQSSTLHDRGITGNSGASLHAKT
                     FSIDGKTVFIGSFNFDPRSTLLNTEMGFVIESETLAQLIDKRFIQSQYDAAWQLRLDR
                     WGRINWVDRHAKKEIILKKEPATSFWKRVMVRLASILPVEWLL"
     gene            complement(4260..5417)
                     /gene="mdoC"
                     /locus_tag="RN951_001165"
     CDS             complement(4260..5417)
                     /gene="mdoC"
                     /locus_tag="RN951_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoC"
                     /protein_id="HDX2526196.1"
                     /translation="MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAES
                     SLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLL
                     TLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRI
                     RNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTL
                     FYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETES
                     VITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHI
                     TSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR"
     gene            5811..7346
                     /gene="mdoG"
                     /locus_tag="RN951_001166"
     CDS             5811..7346
                     /gene="mdoG"
                     /locus_tag="RN951_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoG"
                     /protein_id="HDX2526197.1"
                     /translation="MMKMRWLSAAVMLTLYTSSSWAFSIDDVAKQAQSLAGKGYETPK
                     SNLPSVFRDMKYADYQQIQFNHDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATA
                     VKRIKYSPDYFTFGDVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVI
                     GAGQVYGLSARGLAIDTALPSGEEFPRFKEFWIERPKPTDKRLTIYALLDSPRATGAY
                     KFVVMPGRDTVVDVQSKIYLRDKVGKLGVAPLTSMFLFGPNQPSPANNYRPELHDSNG
                     LSIHAGNGEWIWRPLNNPKHLAVSSFSMENPQGFGLLQRGRDFSRFEDLDDRYDLRPS
                     AWVTPKGEWGKGSVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTITFSRDED
                     KLHAPDNAWVQQTRRSTGDVKQSNLIRQPDGTIAFVVDFTGAEMKKLPEDTPVTAQTS
                     IGDNGEIVESTVRYNPVTKGWRLVMRVKVKDAKKTTEMRAALVNADQTLSETWSYQLP
                     ANE"
     gene            7339..9882
                     /gene="mdoH"
                     /locus_tag="RN951_001167"
     CDS             7339..9882
                     /gene="mdoH"
                     /locus_tag="RN951_001167"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis glucosyltransferase MdoH"
                     /protein_id="HDX2526198.1"
                     /translation="MNKTTEYIDAMPIAASEKAALPKTDIRAVHQALDAEHRTWARED
                     DSPQGSVKARLEQAWPDSLADGQLIKDDEGRDQLKAMPEAKRSSMFPDPWRTNPVGRF
                     WDRLRGRDVTPRYLARLTKEEQESEQKWRTVGTIRRYILLILTLAQTVVATWYMKTIL
                     PYQGWALINPMDMVGQDLWVSFMQLLPYMLQTGILILFAVLFCWVSAGFWTALMGFLQ
                     LLIGRDKYSISASTVGDEPLNPEHRTALIMPICNEDVNRVFAGLRATWESVKATGNAK
                     HFDVYILSDSYNPDICVAEQKAWMELIAEVGGEGQIFYRRRRRRVKRKSGNIDDFCRR
                     WGSQYSYMVVLDADSVMTGDCLCGLVRLMEANPNAGIIQSSPKASGMDTLYARCQQFA
                     TRVYGPLFTAGLHFWQLGESHYWGHNAIIRVKPFIEHCALAPLPGEGSFAGSILSHDF
                     VEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHP
                     VHRAVFLTGVMSYLSAPLWFMFLALSTALQVVHALTEPQYFLQPRQLFPVWPQWRPEL
                     AIALFASTMVLLFLPKLLSILLIWCKGTKEYGGFWRVTLSLLLEVLFSVLLAPVRMLF
                     HTVFVVSAFLGWEVVWNSPQRDDDSTSWGEAFKRHGSQLLLGLVWAVGMAWLDLRFLF
                     WLAPIVFSLILSPFVSVISSRATVGLRTKRWKLFLIPEEYSPPQVLVDTDRFLEMNRQ
                     RSLDDGFMHAVFNPSFNALATAMATARHRASKVLEIARDRHVEQALNETPEKLNRDRR
                     LVLLSDPVTMARLHFRVWNSPERYSSWVSYYEGIKLNPLALRKPDAASQ"
     gene            10055..10282
                     /locus_tag="RN951_001168"
     CDS             10055..10282
                     /locus_tag="RN951_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HDX2526199.1"
                     /translation="MRLIVVSIMVTLLSGCGSIISRTIPGQGHGNQYYPGVQWDVRDS
                     AWRYVTILDLPFSLVFDTLLLPIDIHHGPYE"
     gene            complement(10283..10657)
                     /locus_tag="RN951_001169"
     CDS             complement(10283..10657)
                     /locus_tag="RN951_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309456.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acidic protein MsyB"
                     /protein_id="HDX2526200.1"
                     /translation="MTMYATLEEAIDAAREEFLADNPGIDAEDANVQQFNAQKYVLQD
                     GDIMWQVEFFADEGEEGECLPMLSGEAAQSVFDGDYDEIEIRQEWQEENTLHEWDEGE
                     FQLEPPLDTEEGRAAADEWDER"
     gene            complement(10740..11966)
                     /gene="mdtG"
                     /locus_tag="RN951_001170"
     CDS             complement(10740..11966)
                     /gene="mdtG"
                     /locus_tag="RN951_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtG"
                     /protein_id="HDX2526201.1"
                     /translation="MSPCENDTPINWKRNLIVAWLGCFLTGAAFSLVMPFLPLYVEQL
                     GVTGHSALNMWSGIVFSITFLFSAIASPFWGGLADRKGRKLMLLRSALGMGIVMVLMG
                     LAQNIWQFLILRALLGLLGGFVPNANALIATQVPRNKSGWALGTLSTGGVSGALLGPM
                     AGGLLADSYGLRPVFFITASVLILCFFVTLFCIREKFQPVSKKEMLHMREVVTSLKNP
                     KLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNVAFISGMIASVPGVAALLSAP
                     RLGKLGDRIGPEKILITALIFSVLLLIPMSYVQTPLQLGILRFLLGAADGALLPAVQT
                     LLVYNSSNQIAGRIFSYNQSFRDIGNVTGPLMGAAISANYGFRAVFLVTAGVVLFNAV
                     YSWNSLRRRRIPQVSN"
     gene            complement(12138..13058)
                     /gene="lpxL"
                     /locus_tag="RN951_001171"
     CDS             complement(12138..13058)
                     /gene="lpxL"
                     /locus_tag="RN951_001171"
                     /EC_number="2.3.1.241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid IV(A) lauroyltransferase"
                     /protein_id="HDX2526202.1"
                     /translation="MTNLPKFSTALLHPRYWLTWLGIGVLWLVVQLPYPVIYRLGCGL
                     GKLALRFMKRRAKIVHRNLELCFPEMSEQERRKMVVKNFESVGMGLMETGMAWFWPDR
                     RIARWTEVIGMEHIRDVQAQKRGILLVGIHFLTLELGARQFGMQEPGIGVYRPNDNPL
                     IDWLQTWGRLRSNKSMLDRKDLKGMIKALKKGEVVWYAPDHDYGPRSSVFVPLFAVEQ
                     AATTTGTWMLARMSGACLVPFVPRRKPDGKGYQLIMLPPECSPPLDDAETTAAWMNKV
                     VEKCIMMAPEQYMWLHRRFKTRPEGVPSRY"
     gene            13283..14335
                     /locus_tag="RN951_001172"
     CDS             13283..14335
                     /locus_tag="RN951_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HDX2526203.1"
                     /translation="MPVLHNRISNDALKAKMLAESEPRTTISFYKYFHIADPKATRDA
                     LYQLFTALNVFGRVYLAHEGINAQISVPASNVETFRAQLYAFDPALEGLRLNIALDDD
                     GKSFWVLRMKVRDRIVADGIDDPHFDASNVGEYLQAAEVNAMLDDPDALFIDMRNHYE
                     YEVGHFENALEIPADTFREQLPKAVEMMQAHKDKKIVMYCTGGIRCEKASAWMKHNGF
                     NKVWHIEGGIIEYARKAREQGLPVRFIGKNFVFDERMGERISDEIIAHCHQCGAPCDS
                     HTNCKNDGCHLLFIQCPVCAEKYKGCCSEICCEESALPPEEQRRRRAGRENGNKIFNK
                     SRGRLNTTLCIPDPTE"
     gene            complement(14377..14952)
                     /locus_tag="RN951_001173"
     CDS             complement(14377..14952)
                     /locus_tag="RN951_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceI family protein"
                     /protein_id="HDX2526204.1"
                     /translation="MKKSLLGLTFASLMFSAGSAVAADYKIDKEGQHAFVNFRIQHLG
                     YSWLYGTFKDFDGTFTFDEKNPAADKVNVTINTTSVDTNHAERDKHLRSADFLNTAKY
                     PQATFTSTSVKKDGDELDITGDLTLNGVTKPVTLEAKLIGQGDDPWGGKRAGFEAEGK
                     IKLKDFNIKTDLGPASQEVDLIISVEGVQQK"
     gene            complement(14956..15522)
                     /locus_tag="RN951_001174"
     CDS             complement(14956..15522)
                     /locus_tag="RN951_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
                     /protein_id="HDX2526205.1"
                     /translation="MSFTNTPERYGVISAAFHWLSAIIVYGMFALGLWMVTLSYYDGW
                     YHKAPELHKSIGILLMMGLAIRVLWRVISPPPGPLPSYSPMTRLAARAGHLALYLLLF
                     AIGISGYLISTADGKPISVFGWFDVPATLADAGAQADFAGALHFWLAWSVVVLSVMHG
                     FMALKHHFIDKDDTLKRMLGKSSSDYGV"
     gene            complement(15783..15896)
                     /locus_tag="RN951_001175"
     CDS             complement(15783..15896)
                     /locus_tag="RN951_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706980.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceO family protein"
                     /protein_id="HDX2526206.1"
                     /translation="MRRLLHYLINNIREHLMLYLFLWGLLAIMDLIYVFYF"
     gene            complement(15944..17062)
                     /gene="solA"
                     /locus_tag="RN951_001176"
     CDS             complement(15944..17062)
                     /gene="solA"
                     /locus_tag="RN951_001176"
                     /EC_number="1.5.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-methyl-L-tryptophan oxidase"
                     /protein_id="HDX2526207.1"
                     /translation="MKYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHH
                     GDTRLIRHAYGEGEKYVPLVLRAQTLWDELSRHNEEDPIFVRSGVINLGPADSTFLAN
                     VAHSAEQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAK
                     EAGCAQLFNCPVTAIRHDDDGVTIETADGEYQAKKAIVCAGTWVKDLLPELPVQPVRK
                     VFAWYQADGRYSVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERV
                     PFAEVASDGSKAFPFLRNVLPGIGCCLYGAACTYDNSPDEDFIIDTLPGHDNTLLITG
                     LSGHGFKFASVLGEIAADFAQDKKSDFDLTPFRLSRFQ"
     gene            complement(17177..17431)
                     /gene="bssS"
                     /locus_tag="RN951_001177"
     CDS             complement(17177..17431)
                     /gene="bssS"
                     /locus_tag="RN951_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415578.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssS"
                     /protein_id="HDX2526208.1"
                     /translation="MEKNNEVIQTHPLVGWDISTVDSYDALMLRLHYQTPNKSEQEGT
                     EVGQTLWLTTDVARQFISILEAGIAKIESGDFQVNEYRRH"
     gene            complement(17719..17964)
                     /gene="dinI"
                     /locus_tag="RN951_001178"
     CDS             complement(17719..17964)
                     /gene="dinI"
                     /locus_tag="RN951_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein I"
                     /protein_id="HDX2526209.1"
                     /translation="MRIEVTIAKTSPLPAGAIDALAGELSRRIQYAFPDNEGHVSVRY
                     AAANNLSVIGATKEDKQRISEILQETWESADDWFVSE"
     gene            complement(18038..19084)
                     /gene="pyrC"
                     /locus_tag="RN951_001179"
     CDS             complement(18038..19084)
                     /gene="pyrC"
                     /locus_tag="RN951_001179"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HDX2526210.1"
                     /translation="MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMP
                     NLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAA
                     KLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIES
                     VMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRP
                     HLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTAL
                     GSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLV
                     PFLAGETVRWSVKQ"
     gene            complement(19190..19750)
                     /locus_tag="RN951_001180"
     CDS             complement(19190..19750)
                     /locus_tag="RN951_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDX2526211.1"
                     /translation="MNKFLFAAALIVSGLLVGCNQLTQYTITEQEINQSLAKHNNFSK
                     DIGLPGVADAHIVLTNLTSQIGREEPNKVTLTGDANLDMNSLFGSQKATMKLKLKALP
                     VFDKEKGAIFLKEMEVVDATVQPEKMQTVMQTLLPYLNQALRNYFNQQPAYVLREDGS
                     QGEAMAKKLAKGIEVKPGEIVIPFTD"
     gene            complement(19884..20531)
                     /gene="grxB"
                     /locus_tag="RN951_001181"
     CDS             complement(19884..20531)
                     /gene="grxB"
                     /locus_tag="RN951_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 2"
                     /protein_id="HDX2526212.1"
                     /translation="MKLYIYDHCPYCLKARMIFGLKNIPVELHVLLNDDAETPTRMVG
                     QKQVPILQKDDSRYMPESMDIVHYVDKLDGKPLLTGKRSPAIEEWLRKVNGYANKLLL
                     PRFAKSAFDEFSTPAARKYFVDKKEASAGNFADLLAHSDGLIKNISDDLRALDKLIVK
                     PNAVNGELSEDDIQLFPLLRNLTLVAGINWPSRVADYRDNMAKQTQINLLSSMAI"
     gene            complement(20595..21803)
                     /gene="mdtH"
                     /locus_tag="RN951_001182"
     CDS             complement(20595..21803)
                     /gene="mdtH"
                     /locus_tag="RN951_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415583.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtH"
                     /protein_id="HDX2526213.1"
                     /translation="MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWA
                     AVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLL
                     WFSCLLSGLGGTLFDPPRSALVVKLIRPQQRGRFFSLLMMQDSAGAVIGALLGSWLLQ
                     YDFRLVCATGAVLFVLCAAFNAWLLPAWKLSTVRTPVREGMTRVMRDKRFVTYVLTLA
                     GYYMLAVQVMLMLPIMVNDVAGAPSAVKWMYAIEACLSLTLLYPIARWSEKHFRLEHR
                     LMAGLLIMSLSMMPVGMVSGLQQLFTLICLFYIGSIIAEPARETLSASLADARARGSY
                     MGFSRLGLAIGGAIGYIGGGWLFDLGKSAHQPELPWMMLGIIGIFTFLALGWQFSQKR
                     AARRLLERDA"
     gene            22039..22623
                     /gene="rimJ"
                     /locus_tag="RN951_001183"
     CDS             22039..22623
                     /gene="rimJ"
                     /locus_tag="RN951_001183"
                     /EC_number="2.3.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S5-alanine
                     N-acetyltransferase"
                     /protein_id="HDX2526214.1"
                     /translation="MFGYRSNVPKVRLTTDRLVVRLVHDRDAWRLADYYAENRHFLKP
                     WEPVRDESHCYPSGWQARLGMINEFHKQGSAFYFGLFDPDEKEIIGVANFSNVVRGSF
                     HACYLGYSIGQKWQGKGLMFEALTAAIRYMQRTQHIHRIMANYMPHNKRSGDLLARLG
                     FEKEGYAKDYLLIDGQWRDHVLTALTTPDWTPGR"
     gene            22634..23281
                     /locus_tag="RN951_001184"
     CDS             22634..23281
                     /locus_tag="RN951_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceH family protein"
                     /protein_id="HDX2526215.1"
                     /translation="MKYQLTALEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNR
                     EPVMNLSESEVQEQLDNLVKRHYLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVAL
                     ITTLLLRGAQTPGELRSRAARMYEFSDMAEVESTLEQLANREDGPFVVRLAREPGKRE
                     NRYMHLFSGEVEDQPAVTDMSNAVDGDLQARVEALEIEVAELKQRLDSLLAHLGD"
     gene            23283..24206
                     /locus_tag="RN951_001185"
     CDS             23283..24206
                     /locus_tag="RN951_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDX2526216.1"
                     /translation="MKKIRIGVVGLGGIAQKAWLPVLAAASDWTLQGAWSPTRAKALP
                     ICESWRIPYADSLSSLAASCDAVFVHSSTASHFDVVSTLLNAGVHVCVDKPLAENLRD
                     AERLVELAARKKLTLMVGFNRRFAPLYGELKTQLATAASLRMDKHRSNSVGPHDLYFT
                     LLDDYLHVVDTALWLSGGKASLDGGTLLTNDAGEMLFAEHHFSAGPLQITTCMHRRAG
                     SQRETVQAVTDGALIDITDMREWREERGQGVVHKPIPGWQSTLEQRGFVGCARHFIEC
                     VQNQTVPQTAGEQAVLAQRIVDKIWRDAMSE"
     gene            24316..25851
                     /gene="murJ"
                     /locus_tag="RN951_001186"
     CDS             24316..25851
                     /gene="murJ"
                     /locus_tag="RN951_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HDX2526217.1"
                     /translation="MNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVA
                     FKLPNLLRRIFAEGAFSQAFVPILAEYKSKQGEDATRVFVSYVSGLLTLALAVVTVAG
                     MLAAPWVIMVTAPGFADTADKFALTSQLLKITFPYILLISLASLVGAILNTWNRFSIP
                     AFAPTLLNISMIGFALFAAPYFNPPVLALAWAVTVGGVLQLVYQLPHLKKIGMLVLPR
                     INFHDAGAMRVVKQMGPAILGVSVSQISLIINTIFASFLASGSVSWMYYADRLMEFPS
                     GVLGVALGTILLPSLSKSFASGNHDEYNRLMDWGLRLCFLLALPSAVALGILSGPLTV
                     SLFQYGKFTAFDALMTQRALIAYSVGLIGLIVVKVLAPGFYSRQDIKTPVKIAIVTLI
                     LTQLMNLAFIGPLKHAGLSLSIGLAACLNASLLYWQLRKQKIFTPQPGWMAFLLRLVV
                     AVLVMSGVLLGMLHIMPEWSLGTMPWRLLRLMAVVLAGIAAYFAALAVLGFKVKEFAR
                     RTV"
     gene            complement(25891..26307)
                     /gene="flgN"
                     /locus_tag="RN951_001187"
     CDS             complement(25891..26307)
                     /gene="flgN"
                     /locus_tag="RN951_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis chaperone FlgN"
                     /protein_id="HDX2526218.1"
                     /translation="MTRLAEILDQMSAVLNDLKTVMDQEQQHLSMGQINGSQLQWITE
                     QKSSLLATLDYLEQLRRKEPNTANSVDISQRWQEITVKTQQLRQMNQHNGWLLEGQIE
                     RNQQALEMLKPHQEPTLYGANGQTSTTHRGGKKISI"
     gene            complement(26312..26605)
                     /gene="flgM"
                     /locus_tag="RN951_001188"
     CDS             complement(26312..26605)
                     /gene="flgM"
                     /locus_tag="RN951_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-28 factor FlgM"
                     /protein_id="HDX2526219.1"
                     /translation="MSIDRTSPLKPVSTVQPRETTDAPVTNSRAAKTTASTSTSVTLS
                     DAQAKLMQPGSSDINLERVEALKLAIRNGELKMDTGKIADALINEAQQDLQSN"
     gene            complement(26681..27340)
                     /gene="flgA"
                     /locus_tag="RN951_001189"
     CDS             complement(26681..27340)
                     /gene="flgA"
                     /locus_tag="RN951_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring formation protein
                     FlgA"
                     /protein_id="HDX2526220.1"
                     /translation="MLIIKRSVAIIAILFSPLSTASNLTSQLHNFFSAQLAGVSDEVR
                     VSIRTAPNLLPPCEQPLLSMSNNSRLWGNVNVLARCGNDKRYLQVNVQATGNYVVAAM
                     PIARGGKLEAGNVKLKRGRLDTLPPRTVLDINQLVDAISLRDLSPDQPIQLTQFRQAW
                     RVKAGQRVNVIASGDGFSANAEGQALNNAAVAQNARVRMVSGQVVSGVVDADGNILIN
                     L"
     gene            27495..27911
                     /gene="flgB"
                     /locus_tag="RN951_001190"
     CDS             27495..27911
                     /gene="flgB"
                     /locus_tag="RN951_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HDX2526221.1"
                     /translation="MLDKLDAALRFQQEALNLRAQRQEVLAANIANADTPGYQARDID
                     FASELKKVMQRGRDATSVVALTMTSTQHIPAQALTPPTAELQYRIPDQPSLDGNTVDM
                     DRERTQFADNSLQYQMSLSALSGQIKGMMNVLQSGN"
     gene            27915..28319
                     /gene="flgC"
                     /locus_tag="RN951_001191"
     CDS             27915..28319
                     /gene="flgC"
                     /locus_tag="RN951_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HDX2526222.1"
                     /translation="MALLNIFDIAGSALTAQSQRLNVAASNLANADSVTGPDGQPYRA
                     KQVVFQVNAAPGAATGGVKVADVIESQAPDKLVYEPGNPLADAKGYVKMPNVDVVGEM
                     VNTMSASRSYQANVEVLNTVKSMMLKTLTLGQ"
     gene            28331..29026
                     /gene="flgD"
                     /locus_tag="RN951_001192"
     CDS             28331..29026
                     /gene="flgD"
                     /locus_tag="RN951_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook assembly protein FlgD"
                     /protein_id="HDX2526223.1"
                     /translation="MSIAVTTTDPTNTGVSTTSSSSLTGSNVADLQSSFLTLLVAQLK
                     NQDPTNPMENNELTSQLAQISTVSGIEKLNTTLGSISGQIDNSQSLQASNLIGHGVMI
                     PGTTVLAGTGSEEGAVTTTTPFGVELQQAADKVTATITDKNGAVVRTIDIGELTAGVH
                     SFTWDGTLTDGSTAPNGSYNVAISASNGGTQLVAQPLQFALVQGVIRGNSGNTLDLGT
                     YGTTTLDEVRQII"
     gene            29051..30259
                     /gene="flgE"
                     /locus_tag="RN951_001193"
     CDS             29051..30259
                     /gene="flgE"
                     /locus_tag="RN951_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook protein FlgE"
                     /protein_id="HDX2526224.1"
                     /translation="MAFSQAVSGLNAAATNLDVIGNNIANSATYGFKSGTASFADMFA
                     GSKVGLGVKVAGITQDFTDGTTTNTGRGLDVAISQNGFFRLVDSNGSVFYSRNGQFKL
                     DENRNLVNMQGLQLTGYPATGTPPTIQQGANPTNISIPNTLMAAKTTTTASMQINLNS
                     SDPLPTVTPFSASNADSYNKKGSVTVFDSQGNAHDMSVYFVKTGDNNWQVYTQDSSDP
                     NSIAKTATTLEFNANGTLVDGAMANNIATGAINGAEPATFSLSFLNSMQQNTGANNIV
                     ATTQNGYKPGDLVSYQINDDGTVVGNYSNEQTQLLGQIVLANFANNEGLASEGDNVWS
                     ATQSSGVALLGTAGTGNFGTLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQD
                     QILNTLVNLR"
     gene            30279..31034
                     /gene="flgF"
                     /locus_tag="RN951_001194"
     CDS             30279..31034
                     /gene="flgF"
                     /locus_tag="RN951_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgF"
                     /protein_id="HDX2526225.1"
                     /translation="MDHAIYTAMGAASQTLNQQAVTASNLANASTPGFRAQLNALRAV
                     PVEGLSLPTRTLVTASTPGADMTPGKMDYTSRPLDVALQQDGWLAVQTADGSEGYTRN
                     GSIQVDPTGQLTIQGHPVIGEAGPIAVPEGAEITIAADGTISALNPGDPANTVAPVGR
                     LKLVKATGSEVQRGDDGIFRLSAETQATRGPVLQADPTLRVMSGVLEGSNVNAVAAMS
                     DMIASARRFEMQMKVISSVDDNAGRANQLLSMS"
     gene            31206..31988
                     /gene="flgG"
                     /locus_tag="RN951_001195"
     CDS             31206..31988
                     /gene="flgG"
                     /locus_tag="RN951_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgG"
                     /protein_id="HDX2526226.1"
                     /translation="MISSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDL
                     LYQTIRQPGAQSSEQTTLPSGLQIGTGVRPVATERLHSQGNLSQTNNSKDVAIKGQGF
                     FQVMLPDGSSAYTRDGSFQVDQNGQLVTAGGFQVQPAITIPANALSITIGRDGVVSVT
                     QQGQAAPVQVGQLNLTTFMNDTGLESIGENLYTETQSSGAPNESTPGLNGAGLLYQGY
                     VETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL"
     gene            32041..32739
                     /gene="flgH"
                     /locus_tag="RN951_001196"
     CDS             32041..32739
                     /gene="flgH"
                     /locus_tag="RN951_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body L-ring protein FlgH"
                     /protein_id="HDX2526227.1"
                     /translation="MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPT
                     PVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKT
                     NFGFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGN
                     LHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQN
                     MGWLQRFFLNLSPM"
     gene            32751..33848
                     /gene="flgI"
                     /locus_tag="RN951_001197"
     CDS             32751..33848
                     /gene="flgI"
                     /locus_tag="RN951_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415598.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring protein FlgI"
                     /protein_id="HDX2526228.1"
                     /translation="MIKFLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVG
                     LDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQT
                     IDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQL
                     NGGRITNGAVIERELPSQFGVGNTLNLQLNDEDFSMAQQIADTINRVRGYGSATALDA
                     RTIQVRVPSGNSSQVRFLADIQNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVA
                     QGNLSVTVNRQANVSQPDTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRA
                     LNALGATPMDLMSILQSMQSAGCLRAKLEII"
     gene            33848..34789
                     /gene="flgJ"
                     /locus_tag="RN951_001198"
     CDS             33848..34789
                     /gene="flgJ"
                     /locus_tag="RN951_001198"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly peptidoglycan hydrolase FlgJ"
                     /protein_id="HDX2526229.1"
                     /translation="MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMF
                     VQMMLKSMRDALPKDGLFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQ
                     PLPEESTPAAPMKFPLETVVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPA
                     QLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITT
                     TEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAG
                     YATDPHYARKLTNMIQQMKSISDKVSKTYSMNIDNLF"
     gene            34855..36498
                     /gene="flgK"
                     /locus_tag="RN951_001199"
     CDS             34855..36498
                     /gene="flgK"
                     /locus_tag="RN951_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HDX2526230.1"
                     /translation="MSSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMEQA
                     NSTLGAGGWVGNGVYVSGVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTS
                     TSSLATQMQDFFTSLQTLVSNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNI
                     AIGASVDQINNYAKQIASLNDQISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVS
                     VQDGGTYNITMANGYSLVQGSTARQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLN
                     TGSLGGILTFRSQDLDQTRNTLGQLALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPA
                     VLQNTKNKGDVAIGATVTDASAVLATDYKISFDNNQWQVTRLASNTTFTVTPDANGKV
                     AFDGLELTFTGTPAVNDSFTLKPVSDAIVNMDVLITDEAKIAMASEEDAGDSDNRNGQ
                     ALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQLSNQQQSIS
                     GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR"
     gene            36510..37463
                     /gene="flgL"
                     /locus_tag="RN951_001200"
     CDS             36510..37463
                     /gene="flgL"
                     /locus_tag="RN951_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HDX2526231.1"
                     /translation="MRFSTQMMYQQNMRGITNSQAEWMKYGEQMSTGKRVVNPSDDPI
                     AASQAVVLSQAQAQNSQYTLARTFATQKVSLEESVLSQVTTAIQNAQEKIVYASNGTL
                     SDDDRASLATDIQGLRDQLLNLANTTDGNGRYIFAGYKTETAPFSEEKGKYVGGAESI
                     KQQVDASRSMVIGHTGDKIFDSITSNAVAEPDGSASETNLFAMLDSAIAALKTPVADS
                     EADKETAAAALDKTNRGLKNSLNNVLTVRAELGTQLNELESLDSLGSDRALGQTQQMS
                     DLVDVDWNATISSYIMQQTALQASYKAFTDMQGLSLFQLSK"
     gene            complement(37659..40844)
                     /gene="rne"
                     /locus_tag="RN951_001201"
     CDS             complement(37659..40844)
                     /gene="rne"
                     /locus_tag="RN951_001201"
                     /EC_number="3.1.26.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E"
                     /protein_id="HDX2526232.1"
                     /translation="MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKG
                     KITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQEVIV
                     QIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLEL
                     PEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAF
                     RDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIE
                     SAFQREVRLPSGGSIVIDSTEALTAIDINSARATRGGDIEETAFNTNLEAADEIARQL
                     RLRDLGGLIVIDFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRL
                     SPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASY
                     LLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEE
                     AMALPSEEEFAERKRPEQPALATFAMPDVPPAPTPAEPAAPVVAPAPKAAPATPVAPA
                     QPGLLSRFFGALKALFSGGEETKPTEQPAPKAEAKPERQQDRRKPRQNNRRDRNERRD
                     TRSERTEGSDNREENRRNRRQAQQQTAETRESRQQAEVTEKARTADEQQAPRRERSRR
                     RNDDKRQAQQEAKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSVAEEAV
                     VAPVVEETVAAEPIVQEAPAPRTELVKVPLPVVAQTAPEQQEENNADNRDNGGMPRRS
                     RRSPRHLRVSGQRRRRYRDERYPTQSPMPLTVACASPELASGKVWIRYPIVRPQDVQV
                     EEQREQEEVHVQPMVTEVPVAAAIEPVVSAPVVEEVAGVVEAPVQVAEPQPEVVETTH
                     PEVIAAAVTEQPQVITESDVAVAQKVAEQAEPVVEPQEETADIEEVVETAEVVVAEPE
                     VVAQPAAPVVAEVAAEVETVAAVEPEVTVEHNHATAPMTRAPAPEYVPEAPRHSDWQR
                     PTFAFEGKGAAGGHTATHHASAAPARPQPVE"
     gene            41417..42376
                     /gene="rluC"
                     /locus_tag="RN951_001202"
     CDS             41417..42376
                     /gene="rluC"
                     /locus_tag="RN951_001202"
                     /EC_number="5.4.99.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(955/2504/2580) synthase
                     RluC"
                     /protein_id="HDX2526233.1"
                     /translation="MKTETPSVKIVAITADEAGQRIDNFLRTQLKGVPKSMIYRILRK
                     GEVRVNKKRIKPEYKLEAGDEVRIPPVRVAEREEEAVSPHLQKVAALADVILYEDDHI
                     LVLNKPSGTAVHGGSGLSFGVIEGLRALRPEARFLELVHRLDRDTSGVLLVAKKRSAL
                     RSLHEQLREKGMQKDYLALVRGQWQSHVKSVQAPLLKNILQSGERIVRVSQEGKPSET
                     RFKVEERYAFATLVRCSPVTGRTHQIRVHTQYAGHPIAFDDRYGDREFDRQLTEAGTG
                     LNRLFLHAAALKFTHPGTGEVMRIEAPMDEGLKRCLQKLRNAR"
     gene            complement(42488..43072)
                     /gene="yceF"
                     /locus_tag="RN951_001203"
     CDS             complement(42488..43072)
                     /gene="yceF"
                     /locus_tag="RN951_001203"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415605.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-methyl-GTP pyrophosphatase"
                     /protein_id="HDX2526234.1"
                     /translation="MPKLILASTSPWRRALLEKLQISFECAAPEVDETPRSDESPRQL
                     VLRLAQEKAQSLASRYPDHLIIGSDQVCVLDGEITGKPLTEENARLQLRKASGNIVTF
                     YTGLALFNSANGHLQTEVEPFDVHFRHLSEAEIDNYVRKEHPLHCAGSFKSEGFGITL
                     FERLEGRDPNTLVGLPLIALCQMLRREGKNPLMG"
     gene            43271..43792
                     /gene="yceD"
                     /locus_tag="RN951_001204"
     CDS             43271..43792
                     /gene="yceD"
                     /locus_tag="RN951_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA accumulation protein YceD"
                     /protein_id="HDX2526235.1"
                     /translation="MQKVKLPLTLDPVRTAQKRLDYQGIYTPDQVERVAESVVSVDSD
                     VECSMSFAIDNQRLAVLNGDAKVTVTLECQRCGKPFTHQVYTTYCFSPVRSDEQAEAL
                     PEAYEPIEVNEFGEIDLLAMVEDEIILALPVVPVHDSEHCEVSEADMVFGELPEEAQK
                     PNPFAVLASLKRK"
     gene            43844..44017
                     /gene="rpmF"
                     /locus_tag="RN951_001205"
     CDS             43844..44017
                     /gene="rpmF"
                     /locus_tag="RN951_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDX2526236.1"
                     /translation="MAVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHIT
                     ADGYYRGRKVIAK"
     gene            44098..45168
                     /gene="plsX"
                     /locus_tag="RN951_001206"
     CDS             44098..45168
                     /gene="plsX"
                     /locus_tag="RN951_001206"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415608.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HDX2526237.1"
                     /translation="MTRLTLALDVMGGDFGPSVTVPAALQALNSNSQLTLLLVGNPDA
                     ITPLLAKADFEQRSRLQIIPAQSVIASDARPSQAIRASRGSSMRVALELVKEGRAQAC
                     VSAGNTGALMGLAKLLLKPLEGIERPALVTVLPHQQKGKTVVLDLGANVDCDSTMLVQ
                     FAIMGSVLAEEVVEIPNPRVALLNIGEEEVKGLDSIRDASAVLKTIPSINYIGYLEAN
                     ELLTGKTDVLVCDGFTGNVTLKTMEGVVRMFLSLLKSQGEGKKRSWWLLLLKRWLQKS
                     LTRRFSHLNPDQYNGACLLGLRGTVIKSHGAANQRAFAVAIEQAVQAVQRQVPQRIAA
                     RLESVYPAGFELLDGGKSGTLR"
     gene            45236..46189
                     /gene="fabH"
                     /locus_tag="RN951_001207"
     CDS             45236..46189
                     /gene="fabH"
                     /locus_tag="RN951_001207"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HDX2526238.1"
                     /translation="MYTKIIGTGSYLPEQVRTNADLEKMVDTSDEWIVTRTGIRERHI
                     AAPNETVSTMGFEAATRAIEMAGIEKDQIGLIVVATTSATHAFPSAACQIQSMLGIKG
                     CPAFDVAAACAGFTYALSVADQYVKSGAVKYALVVGSDVLARTCDPTDRGTIIIFGDG
                     AGAAVLAASEEPGIISTHLHADGSYGELLTLPNADRVNPENSIHLTMAGNEVFKVAVT
                     ELAHIVDETLAANNLDRSQLDWLVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTS
                     AASVPCALDEAVRDGRIKPGQLVLLEAFGGGFTWGSALVRF"
     gene            46205..47134
                     /gene="fabD"
                     /locus_tag="RN951_001208"
     CDS             46205..47134
                     /gene="fabD"
                     /locus_tag="RN951_001208"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDX2526239.1"
                     /translation="MTQFAFVFPGQGSQTVGMLADMAASYPIVEETFAEASAALGYDL
                     WALTQQGPAEELNKTWQTQPALLTASVALYRVWQQQGGKAPAMMAGHSLGEYSALVCA
                     GVIDFADAVRLVEMRGKFMQEAVPEGTGAMAAIIGLDDASIAKACEEAAEGQVVSPVN
                     FNSPGQVVIAGHKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPAADKLAVELAK
                     ITFNAPTVPVVNNVDVKCETNGDAIRDALVRQLYNPVQWTKSVEYMAAQGVEHLYEVG
                     PGKVLTGLTKRIVDTLTASALNEPSAMAAALEL"
     gene            47147..47881
                     /gene="fabG"
                     /locus_tag="RN951_001209"
     CDS             47147..47881
                     /gene="fabG"
                     /locus_tag="RN951_001209"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="HDX2526240.1"
                     /translation="MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQA
                     ISDYLGANGKGLMLNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEE
                     WNDIIETNLSSVFRLSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIG
                     FSKSLAREVASRGITVNVVAPGFIETDMTRALSDDQRAGILAQVPAGRLGGAQEIANA
                     VAFLASDEAAYITGETLHVNGGMYMV"
     gene            48092..48328
                     /gene="acpP"
                     /locus_tag="RN951_001210"
     CDS             48092..48328
                     /gene="acpP"
                     /locus_tag="RN951_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDX2526241.1"
                     /translation="MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELV
                     MALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA"
     gene            48416..49657
                     /gene="fabF"
                     /locus_tag="RN951_001211"
     CDS             48416..49657
                     /gene="fabF"
                     /locus_tag="RN951_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HDX2526242.1"
                     /translation="MSKRRVVVTGLGMLSPVGNTVESTWKALLAGQSGISLIDHFDTS
                     AYATKFAGLVKDFNCEDIISRKEQRKMDAFIQYGIVAGVQAMQDSGLEITEENATRIG
                     AAIGSGIGGLGLIEENHTSLMNGGPRKISPFFVPSTIVNMVAGHLTIMYGLRGPSISI
                     ATACTSGVHNIGHAARIIAYGDADVMVAGGAEKASTPLGVGGFGAARALSTRNDNPQA
                     ASRPWDKERDGFVLGDGAGMLVLEEYEHAKKRGAKIYAELVGFGMSSDAYHMTSPPEN
                     GAGAALAMANALRDAGIEASQIGYVNAHGTSTPAGDKAEAQAVKTIFGEAASRVLVSS
                     TKSMTGHLLGAAGAVESIYSILALRDQAVPPTINLDNPDEGCDLDFVPHEARQVSGME
                     YTLCNSFGFGGTNGSLIFKKI"
     gene            49777..50586
                     /gene="pabC"
                     /locus_tag="RN951_001212"
     CDS             49777..50586
                     /gene="pabC"
                     /locus_tag="RN951_001212"
                     /EC_number="4.1.3.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate lyase"
                     /protein_id="HDX2526243.1"
                     /translation="MFLINGHKQESLAVSDRATQFGDGCFTTARVIDGKVSLLSAHIQ
                     RLQDACQRLMISCDFWPQLEQEMKTLAAEQQNGVLKVVISRGSGGRGYSTLNSGPATR
                     ILSVTAYPAHYDRLRNEGITLALSPVRLGRNPHLAGIKHLNRLEQVLIRSHLEQTNAD
                     EALVLDSEGWVTECCAANLFWRKGNVVYTPRLDQAGVNGIMRQFCIRLLAQSSYQLVE
                     VQASLEESLQADEMVICNALMPVMPVCACGDVSFSSATLYEYLAPLCERPN"
     gene            50589..51611
                     /gene="yceG"
                     /locus_tag="RN951_001213"
     CDS             50589..51611
                     /gene="yceG"
                     /locus_tag="RN951_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein YceG"
                     /protein_id="HDX2526244.1"
                     /translation="MKKVLLIILLLLVVLGIAAGVGVWKVRHLADSKLLIKEETIFTL
                     KPGTGRLALGEQLYADKIINRPRVFQWLLRIEPDLSHFKAGTYRFTPQMTVREMLKLL
                     ESGKEAQFPLRLVEGMRLSDYLKQLREAPYIKHTLSDDKYATVAQALELENPEWIEGW
                     FWPDTWMYTANTTDVALLKRAHKKMVKAVDSAWEGRADGLPYKDKNQLVTMASIIEKE
                     TAVASERDKVASVFINRLRIGMRLQTDPTVIYGMGERYNGKLSRADLETPTAYNTYTI
                     TGLPPGAIATPGADSLKAAAHPAKTPYLYFVADGKGGHTFNTNLASHNKSVQDYLKVL
                     KEKNAQ"
     gene            51601..52242
                     /locus_tag="RN951_001214"
     CDS             51601..52242
                     /locus_tag="RN951_001214"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HDX2526245.1"
                     /translation="MRSKYIVIEGLEGAGKTTARNVVVETLEQLGIRDMVFTREPGGT
                     QLAEKLRSLVLDIKSVGDEVITDKAEVLMFYAARVQLVETVIKPALANGTWVIGDRHD
                     LSTQAYQGGGRGIDQHMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGELDRIE
                     QESFDFFNRTRARYLELAAQDKSIHTIDATQPLEAVMDAIRTTVTHWVKELDA"
     gene            52239..53243
                     /gene="holB"
                     /locus_tag="RN951_001215"
     CDS             52239..53243
                     /gene="holB"
                     /locus_tag="RN951_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HDX2526246.1"
                     /translation="MRWYPWLRPDFEKLVASYQAGRGHHALLIQALPGMGDDALIYAL
                     SRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPEKGKNTLGVDAVREVTEKLNE
                     HARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR
                     LHYLAPPPEQYAVTWLSREVTMSQDALLAALRLSAGSPGAALALFQGDNWQARETLCQ
                     ALAYSVPSGDWYSLLAALNHEQAPARLHWLATLLMDALKRHHGAAQVTNVDVPGLVAE
                     LANHLSPSRLQAILGDVCHIREQLMSVTGINRELLITDLLLRIEHYLQPGVVLPVPHL
                     "
     gene            53254..54051
                     /locus_tag="RN951_001216"
     CDS             53254..54051
                     /locus_tag="RN951_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDX2526247.1"
                     /translation="MFLVDSHCHLDGLDYESLHKDVDDVLAKAAARDVKFCLAVATTL
                     PGYLHMRDLVGERDNVVFSCGVHPLNQNDPYDVEDLRRLAAEEGVVALGETGLDYYYT
                     PETKVRQQESFIHHIQIGRELNKPVIVHTRDARADTLAILREEKVTDCGGVLHCFTED
                     RETAGKLLDLGFYISFSGIVTFRNAEQLRDAARYVPLDRLLVETDSPYLAPVPHRGKE
                     NQPAMVRDVAEYMAVLKGVAVEELAQVTTDNFARLFHIDASRLQSIR"
     gene            54346..55779
                     /gene="ptsG"
                     /locus_tag="RN951_001217"
     CDS             54346..55779
                     /gene="ptsG"
                     /locus_tag="RN951_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIBC"
                     /protein_id="HDX2526248.1"
                     /translation="MFKNAFANLQKVGKSLMLPVSVLPIAGILLGVGSANFSWLPAVV
                     SHVMAEAGGSVFANMPLIFAIGVALGFTNNDGVSALAAVVAYGIMVKTMAVVAPLVLH
                     LPAEEIASKHLADTGVLGGIISGAIAAYMFNRFYRIKLPEYLGFFAGKRFVPIISGLA
                     AIFTGVVLSFIWPPIGSAIQTFSQWAAYQNPVVAFGIYGFIERCLVPFGLHHIWNVPF
                     QMQIGEYTNAAGQVFHGDIPRYMAGDPTAGKLSGGFLFKMYGLPAAAIAIWHSAKPEN
                     RAKVGGIMISAALTSFLTGITEPIEFSFMFVAPILYIIHAILAGLAFPICILLGMRDG
                     TSFSHGLIDFIVLSGNSSKLWLFPIVGIGYAIVYYTIFRVLIKALDLKTPGREDATED
                     AKATGTSEMAPALVAAFGGKENITNLDACITRLRVSVADVSKVDQAGLKKLGAAGVVV
                     AGSGVQAIFGTKSDNLKTEMDEYIRNH"
     gene            complement(55839..58028)
                     /gene="fhuE"
                     /locus_tag="RN951_001218"
     CDS             complement(55839..58028)
                     /gene="fhuE"
                     /locus_tag="RN951_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric-rhodotorulic acid/ferric-coprogen
                     receptor FhuE"
                     /protein_id="HDX2526249.1"
                     /translation="MLSTQFNRDNQYQAITKPSLLAGCIALALLPSAAFAAPATEETV
                     IVEGSATAPDDGENDYSVTSTSAGTKMQMTQRDIPQSVTIVSQQRMEDQQLQTLGEVM
                     ENTLGISKSQADSDRALYYSRGFQIDNYMVDGIPTYFESRWNLGDALSDMALFERVEV
                     VRGATGLMTGTGNPSAAINMVRKHATSREFKGDVSAEYGSWNKERYVADLQSPLTEDG
                     KIRARIVGGYQNNDSWLDRYNSEKTFFSGIVDADLGDLTTLSAGYEYQRIDVNSPTWG
                     GLPRWNTDGSSNSYDRARSTAPDWAYNDKEINKVFMTLKQQFADTWQATLNATHSEVE
                     FDSKMMYVDAYVNKADGMLVGPYSNYGPGFDYVGGTGWNSGKRKVDALDLFADGSYEL
                     FGRQHNLMFGGSYSKQNNRYFSSWANIFPDEIGSFYNFNGNFPQTDWSPQSLAQDDTT
                     HMKSLYAATRVTLADPLHLILGARYTNWRVDTLTYSMEKNHTTPYAGLVFDINDNWST
                     YASYTSIFQPQNDRDSSGKYLAPITGNNYELGLKSDWMNSRLTTTLAIFRIEQDNVAQ
                     STGTPIPGSNGETAYKAVDGTVSKGVEFELNGAITDNWQLTFGATRYIAEDNEGNAVN
                     PNLPRTTVKMFTSYRLPVMPELTVGGGVNWQNRVYTDTVTPYGTFRAEQGSYALVDLF
                     TRYQVTKNFSLQGNVNNLFDKTYDTNVEGSIVYGTPRNFSITGTYQF"
     gene            58362..58721
                     /gene="hinT"
                     /locus_tag="RN951_001219"
     CDS             58362..58721
                     /gene="hinT"
                     /locus_tag="RN951_001219"
                     /EC_number="3.9.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415621.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleoside phosphoramidase"
                     /protein_id="HDX2526250.1"
                     /translation="MAEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIP
                     NILIPTVNDVSAEHEQALGRMITVAAKIAEQEGIAEDGYRLIMNTNRHGGQEVYHIHM
                     HLLGGRPLGPMLAHKGL"
     gene            58724..59101
                     /locus_tag="RN951_001220"
     CDS             58724..59101
                     /locus_tag="RN951_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcfL family protein"
                     /protein_id="HDX2526251.1"
                     /translation="MRKGCFGLVSLVLLLLVGCRSHPEIPVNDEQSLVMESSLLAAGI
                     SAEKPFLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHPLERPRSVTIPAH
                     SAVTLYGSANFLGAHKVRLYLYL"
     gene            59115..59756
                     /gene="lpoB"
                     /locus_tag="RN951_001221"
     CDS             59115..59756
                     /gene="lpoB"
                     /locus_tag="RN951_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator LpoB"
                     /protein_id="HDX2526252.1"
                     /translation="MTKMSRYALITALAMFLAGCVGQREPAPVEEVKPAPEQPAEPQQ
                     PVPTVPSVPTIPQQPGPIEHEDQTAPPAPHIRYYDWNGAMQPMVSKMLGADGVTAGSV
                     LLVDSVNNRTNGSLNAAEATETLRNALANNGKFTLVSAQQLSMAKQQLGLSPQDSLGT
                     RSKAIGIARNVGAHYVLYSSASGNVNAPTLQMQLMLVQTGEIIWSGKGAVSQQ"
     gene            59737..60561
                     /gene="thiK"
                     /locus_tag="RN951_001222"
     CDS             59737..60561
                     /gene="thiK"
                     /locus_tag="RN951_001222"
                     /EC_number="2.7.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine kinase"
                     /protein_id="HDX2526253.1"
                     /translation="MPFRSNNPITRDELLSRFFPQYHPVTTFNSGLSGGSFLIEHQGQ
                     RFVVRQPHDPDAPQSAFLRQYRALSQLPACIAPKPHLYLRDWMVVDYLPGAVKTYLPD
                     TNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRMLKRLRKAREPRP
                     LRLSPLHMDVHAGNLVHSASGLKLIDWEYAGDGDIALELAAVWVENTEQHRQLVNDYA
                     TRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ"
     gene            60572..61597
                     /gene="nagZ"
                     /locus_tag="RN951_001223"
     CDS             60572..61597
                     /gene="nagZ"
                     /locus_tag="RN951_001223"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HDX2526254.1"
                     /translation="MGPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRE
                     LVRQIRAASRNRLVVAVDQEGGRVQRFREGFTRLPAAQSFAALSGMEEGGKLAQEAGW
                     LMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPQKALAIASRFIDGMHEAGMKT
                     TGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSD
                     VDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERGQASLDAGCDMI
                     LVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARWKAISTRLNQLHERW
                     QEEKAGH"
     gene            61620..62162
                     /locus_tag="RN951_001224"
     CDS             61620..62162
                     /locus_tag="RN951_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDX2526255.1"
                     /translation="MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLISYSTRHPKHDMQ
                     HLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVIFNPNLFPYENMEGKI
                     DRPEEYADIATKCVTNFREKNRDRCLVILSRNDEALNSQRTSEELHHYYEIVWDEEQT
                     HKFKNISPHLQRIKAFKTLG"
     gene            62562..63866
                     /gene="ndh"
                     /locus_tag="RN951_001225"
     CDS             62562..63866
                     /gene="ndh"
                     /locus_tag="RN951_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017384716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone dehydrogenase"
                     /protein_id="HDX2526256.1"
                     /translation="MTTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHS
                     HLWKPLLHEVATGSLDEGVDALSYLAHARNHGFQFQLGSVIDIDREAKTITIAELRDE
                     KGELLVPERKIAYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFHQEMLNLFLK
                     YSANLGANGKVNIAIVGGGATGVELSAELHNAVKQLHSYGYKGLTNEALNVTLVEAGE
                     RILPALPPRISAAAHNELTKLGVRVLTQTMVTSADEGGLHTKDGEYIEADLMVWAAGI
                     KAPDFLKDIGGLETNRINQLVVEPTLQTTRDPDIYAIGDCASCPRPEGGFVPPRAQAA
                     HQMATCAMNNILAQMNGKPLKNYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGRI
                     ARFVYISLYRMHQIALHGYFKTGLMMLVGSINRVIRPRLKLH"
     gene            64076..64615
                     /locus_tag="RN951_001226"
     CDS             64076..64615
                     /locus_tag="RN951_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HDX2526257.1"
                     /translation="MNKSMLAGIGIGVAAALGVAAVASLNVFERGPQYAQVVSATPIK
                     ETVKTPRQECRNVTVTHRRPVQDENRITGSVLGAVAGGVIGHQFGGGRGKDVATVVGA
                     LGGGYAGNQIQGSLQESDTYTTTQQRCKTVYDKSEKMLGYDVTYKIGDQQGKIRMDRD
                     PGTQIPLDSNGQLILNNKV"
     gene            complement(64677..65309)
                     /gene="comR"
                     /locus_tag="RN951_001227"
     CDS             complement(64677..65309)
                     /gene="comR"
                     /locus_tag="RN951_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415629.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family copper-responsive transcriptional
                     repressor ComR"
                     /protein_id="HDX2526258.1"
                     /translation="MATDSTQCVKKSRGRPKVFDRDAALDKAMKLFWQHGYEATSLAD
                     LVEATGAKAPTLYAEFTNKEGLFRAVLDRYIDRFAAKHEAQLFCEEKSVESALADYFA
                     AIANCFTSKDTPAGCFMINNCTTLSPDSGDIANTLKSRHAMQERTLQQFLCQRQARGE
                     IPPHCDVTHLAEFLNCIIQGMSISAREGASLEKLMQIAGTTLRLWPELVK"
BASE COUNT        15995 a        16053 c        17377 g        15968 t
ORIGIN      
        1 atgcatataa aaaatatttc ggtgtagtcc tttcgtcatg taaaacgttc ttgttttttc
       61 tccacacctc cgtggacaat tttttactgc aaaaagacga ggtttgtcac ggcttgtgcg
      121 caagacatat cgcagcaatc agcgacgggc aagaagaatg actgtctggt gctttttgat
      181 agcggaaaac ggagatttaa aagaaaacaa aatatttttt tgcgtagata acagcgtatt
      241 tacgtgggtt ttaatacttt ggtatgaact aaaaaagaaa aatacaacgc gcgggtgagt
      301 tattaaaaat atttccgcag acatactttc catcgtaacg cagcgttaac aaaatacagg
      361 ttgcgttaac aaccaagttg aaatgattta atttcttaaa tgtacgacca ggtccagggt
      421 gacaacatga aaaacaaatt gttatttatg atgttaacaa tactgggtgc gcctgggatt
      481 gcagccgcag caggttatga tttagctaat tcagaatata acttcgcggt aaatgaattg
      541 agtaagtctt catttaatca ggcagccata attggtcaag ctgggactaa taatagtgct
      601 cagttacggc agggaggctc aaaacttttg gcggttgttg cgcaagaagg tagtagcaac
      661 cgggcaaaga ttgaccagac aggagattat aaccttgcat atattgatca ggcgggcagt
      721 gccaacgatg ccagtatttc gcaaggcgct tatggtaata ctgcgatgat tatccagaaa
      781 ggttctggta ataaagcaaa tattacacag tatggtactc aaaaaacggc aattgtagtg
      841 cagagacagt cgcaaatggc tattcgcgtg acacaacgtt aatttccatt cgacttttaa
      901 atcaatccga tgggggtttt acatgaaact tttaaaagta gcagcaattg cagcaatcgt
      961 attctccggt agcgctctgg caggtgttgt tcctcagtac ggcggcggcg gtaaccacgg
     1021 tggtggcggt aataatagcg gcccaaattc tgagctgaac atttaccagt acggtggcgg
     1081 taactctgca cttgctctgc aaactgatgc ccgtaactct gacttgacta ttacccagca
     1141 tggcggcggt aatggtgcag atgttggtca gggctcagat gacagctcaa tcgatctgac
     1201 ccaacgtggc ttcggtaaca gcgctactct tgatcagtgg aacggcaaaa attctgaaat
     1261 gacggttaaa cagttcggtg gtggcaacgg tgctgcagtt gaccagactg catctaactc
     1321 ctccgtcaac gtgactcagg ttggctttgg taacaacgcg accgctcatc agtactaata
     1381 catcatttgt attacagaaa cagggcgcaa gccctgtttt ttttcgggag aagaatatga
     1441 atacgttatt actccttgcg gcactttcca gtcagataac ctttaatacg acccagcaag
     1501 gggatgtgta taccattatt cctgaagtca ctcttactca atcttgtctg tgcagagtac
     1561 aaatattatc cctgcgcgaa ggcagttcag ggcaaagtca gacgaagcaa gaaaagaccc
     1621 tttcattgcc tgctaatcaa cccattgctt tgacgaagtt gagtttaaat atttccccgg
     1681 acgatcgggt gaaaatagtt gttactgttt ctgatggaca gtcacttcat ttatcacaac
     1741 aatggccgcc ctcttcagaa aagtcttaat ttgttgaaat atcgagcata agatgaatct
     1801 ggagagaatg gtctgctgcg aatcagccaa cctgaaagta tggataacac aaccctcaag
     1861 gatgactaat cattgaggaa atagaataaa tgttcagacc ttttttaaac tctcttatgc
     1921 tcggcagttt gttttttcct tttattgcca ttgctggaag caccgtgcaa gggggcgtga
     1981 tccattttta tggccaaatt gtggaaccgg catgtgacgt cagcacccag tcatcacccg
     2041 tagaaatgaa ctgcccacag aatggttcta ttccgggcaa aacctactcc agcaaagcgt
     2101 taatgagcgg caatgtcaaa aacgcgcaaa tagcctcagt aaaagtgcag tatcttgata
     2161 aacagaaaaa gctggctgta atgaacatcg aatataacta agtttctgaa caactcacgt
     2221 tgctgagcag aaaaatgcga tttaaccaaa aagcctgctg tacacttaag aaacaagaag
     2281 gtgtaaggag gcgttatgaa aacgcgtatt catgttgtgc agggtgatat taccaaactg
     2341 gccgttgatg tgattgtgaa tgcggctaat ccgtcattaa tgggaggcgg cggcgtcgat
     2401 ggggccattc atcgcgcagc gggtccggcc ctgctggatg cttgtttaaa agtcaggcaa
     2461 cagcagggcg attgccctac ggggcatgcc gttattacgc ttgcaggcga tcttcccgct
     2521 aaagccgtag tgcacaccgt cgggccagtc tggcgtggtg gtgaacaaaa cgaagaccag
     2581 cttttgcagg atgcctatct caatagccta cgactggtgg cggcaaacag ctatacgtca
     2641 gtggcttttc ctgcaatcag tactggggtt tatggttacc ctcgtgcggc agcggctgaa
     2701 atcgcagtaa aaaccgtttc agaatttatt acccgtcacg ctttacccga acaggtatac
     2761 tttgtctgtt atgatgaaga aaacgcccac ctctacgaaa gactccttac ccaacaagga
     2821 gatgaatgat ttgccccggc tggcgagcgc ggtgctgcca ctgtgttcgc aacatcccgg
     2881 tcagtgtggc ctttttcctc tggagaaaag tctggatgcg tttgccgccc ggtatcgtct
     2941 ggccgaaatg gcagagcata cgctcgatgt tcagtattac atctggcagg acgatatgtc
     3001 gggtcggtta ctgttttccg ccctgttagc cgcagcaaag cgtggcgttc gcgtccgttt
     3061 gttgctggac gacaacaata cgcccggact tgacgacatt ttacgcttgc ttgacagtca
     3121 tccacgcatt gaagtccggc tttttaatcc tttctcgttt cgcttgctgc gtccgcttgg
     3181 ttatatcacc gacttttccc gtcttaatcg ccgtatgcac aataaaagtt tcactgtcga
     3241 tggcgtggtg accctggtgg gaggacgaaa tattggtgat gcctattttg gagcagggga
     3301 ggagccactt ttttcggatt tagatgtcat ggcaatagga cccgtggtag aggacgttgc
     3361 cgatgatttc gcccgctact ggtattgcaa atcggtttca cccttacagc aggtgctgga
     3421 tgtcccggag ggtgaaatgg cggatcgcat cgagttaccc gcctcctggc ataacgatgc
     3481 catgacgcat cgttatttac gcaaaatgga atccagtcca tttataaatc atctggttga
     3541 tggaacattg ccgcttatct gggcgaagac acgtttatta agtgatgatc cggcgaaagg
     3601 ggagggcaag gcaaaacggc attcactgtt accgcagcgc ctgttcgata tcatgggctc
     3661 acccagtgaa cgcatcgata ttatctcttc ctattttgta ccgacacgcg caggtgtggc
     3721 gcaactctta cggatggtga gaaaaggggt aaagattgcg atcctaacca attctcttgc
     3781 cgctaacgat gttgctgtcg tccatgccgg atacgcgcgc tggcgcaaaa aattgctccg
     3841 ctatggcgtg gaattatatg aactcaagcc gacgcgtgaa caaagtagta cgttacacga
     3901 tcgcggcata accggtaatt ccggagccag cctgcatgct aaaaccttta gcatcgatgg
     3961 taaaacggtg tttatcggct ctttcaattt cgatccgcgt tcaacattgc tcaatactga
     4021 aatgggcttc gtgatagaga gcgaaacgct ggcacagtta attgataaac gctttattca
     4081 gagccagtat gatgcggcct ggcagctccg tctggacagg tggggacgga tcaactgggt
     4141 tgatcgtcat gcaaagaaag agattattct caaaaaagaa cccgccacca gtttctggaa
     4201 gcgggttatg gtcagactgg cgtcgatatt gcccgtggaa tggttattgt aaatgtggct
     4261 taacgggctg gtgctttatc gttctcacgc ttaacaaccg gtttaccaga gaacaaaaac
     4321 ttcagtaacg ggatgcgcaa atgaatttca tacagaatta tcgcaatccc tactacaaat
     4381 atcaggccac agagaaaacc aagccagttg gaggtgatgt gcggtgtaat gtatgcgccg
     4441 aaaaacagcg ttaacgggtg gtgaaccaga tagataaaca gcgatgcgtt aacaaaataa
     4501 gtcacccgcg ctgactggaa gttaagcaaa cggtggccaa aggagaagac cacattcacc
     4561 atccacagac cgaggaccat ggtgatcacc gactcggttt cgtacatcca ggcatcgcca
     4621 ctgccatagc gctggttgag taaataagcg acaaacgcca atgctgctgc aagggtacag
     4681 ccacgagacg gcgtggtaaa caaggcttta agatgaggga aaatgaaagc cagtgcgccg
     4741 aggataaaga acggcaaata aaacagcgtt tgcatgacaa taaaattgaa catgccatta
     4801 ctcagaatgg gcggatacac aataaaaatc gttcttctta ttaccgcata accgatgccg
     4861 aggcataaaa aaatcaccga tagttttacc atcgagaatt ttttattcgt tttatcagaa
     4921 ttttctaaat tatttctgat gcgcttaaat atccatacgc acagcgtcgt catgaccact
     4981 aacaccagta aaaaccacag gtgtgatatt aattcccagg ccaacgtatt atatttgtca
     5041 tacaatgaca gcccaggcca actttccgct tttcctttga catattgcag cataataaat
     5101 tgcggtaatg tcagtagggg gatggctgtt aacatcggga tacctacacg ttcgacacgt
     5161 actttccacc attttttcaa gggatagcgt aaaaaaagca tgtaggaaaa gtagccggat
     5221 ataacgaaaa atacctgcat gcggaacgag tggatgaagt cattaaaaag ggtcagccac
     5281 aatgatgatt cggcgctatt cacatgccat gtatggctcg aatagattaa agaaatatga
     5341 aaaggtatcc ctaacaacat cagccaggcg cggatggagt cgaggaaata ttcacgttgc
     5401 gcgggtactg ggttcatata tggttaacta atctcggatt tttcgtctta tccctgtcgg
     5461 gttatgcctt taggcttgtt gccatagtga caccgacctg accgcgccag gcgcaggctt
     5521 caaggttttt atgcatagca tcatcgctac cactaaccag aatggaagcg tctgtaagac
     5581 ggttgataaa taaatttgct ggcaaaccct acacgaagtc gatgcttctg tctttaggag
     5641 aagcacggaa agtgaaaacg gttgcaatca ggtgcttaat ccatgagcca gcgtgctgaa
     5701 cgataccggg attctgttgt cggaatggct ggttatccat taaaatagat cggatcgata
     5761 taagcacaca aagggggaag tgcttactaa ttatgaaaca taaactacaa atgatgaaaa
     5821 tgcgttggtt gagtgctgca gtaatgttaa ccctgtatac atcttcaagc tgggctttca
     5881 gtattgatga tgtcgcaaag caagctcaat ctttagccgg gaaaggctac gagacgccca
     5941 aaagcaactt gccctccgtt ttccgcgata tgaaatacgc ggactatcag cagatccagt
     6001 ttaatcatga caaagcgtac tggaacaatc tgaagacccc attcaaactc gagttctacc
     6061 atcagggtat gtacttcgat accccggtca aaataaatga agtgactgcc accgcagtca
     6121 aacgaatcaa atacagcccg gattatttca ctttcggcga tgttcagcat gacaaagata
     6181 cggtaaaaga ccttggcttt gccggtttta aagtgcttta cccgatcaac agcaaagata
     6241 aaaacgatga aatcgtcagc atgctcgggg ccagctattt ccgcgtgatt ggtgcaggtc
     6301 aggtttatgg cctttctgcc cgcggcctgg caattgatac cgccttgcca tcgggtgaag
     6361 aatttccgcg cttcaaagag ttctggatcg agcgtccaaa accgactgat aaacgtttaa
     6421 ccatctatgc attgcttgac tcgccgcgtg cgacaggtgc ttacaaattc gtggttatgc
     6481 cagggcgtga cacggttgtg gatgtgcagt cgaaaatcta tctgcgcgat aaagtcggca
     6541 aactgggggt tgcaccgtta accagtatgt tcctgtttgg gccgaaccaa ccgtcgcctg
     6601 caaataacta tcgtccggag ttgcacgact ctaacggtct ctctatccat gccggtaatg
     6661 gcgaatggat ctggcgtccg ttgaataacc cgaaacattt agcggtcagc agcttctcca
     6721 tggaaaaccc gcaaggcttt ggtctgttgc agcgcggtcg tgatttctcc cgctttgaag
     6781 atctcgatga tcgttacgat ctccgtccaa gcgcatgggt gactccgaaa ggggagtggg
     6841 gtaaaggcag cgttgagctg gtggaaattc caaccaacga tgaaaccaac gataacatcg
     6901 tcgcttactg gacgccggat cagctgccgg agccgggtaa agagatgaac tttaaataca
     6961 ccatcacctt cagccgtgat gaagacaaac tgcatgcgcc agataacgca tgggtgcaac
     7021 aaacgcgtcg ttcaacgggg gatgtgaagc agtcgaacct gattcgccag cctgacggta
     7081 ctatcgcctt tgtggtcgat tttaccggcg cagagatgaa aaaactgcca gaggataccc
     7141 cggtcacagc gcaaaccagc attggtgata atggtgagat agttgaaagc acggtgcgct
     7201 ataacccggt taccaaaggc tggcgtctgg tgatgcgtgt gaaagtgaaa gatgccaaga
     7261 aaaccactga aatgcgtgct gcgctggtga atgccgatca gacgttgagt gaaacctgga
     7321 gctaccagtt acctgccaat gaataagaca actgagtaca ttgacgcaat gcccatcgcc
     7381 gcaagcgaga aagcggcatt gccgaagact gatatccgcg ccgttcatca ggcgctggat
     7441 gccgaacacc gcacctgggc gcgggaggat gattccccgc aaggctcggt aaaggcgcgt
     7501 ctggaacaag cctggccaga ttcacttgct gatggacagt taattaaaga cgacgaaggg
     7561 cgcgatcagc tgaaggcgat gccagaagca aaacgctcct cgatgtttcc cgacccgtgg
     7621 cgtaccaacc cggtaggccg tttctgggat cgcctgcgtg gacgcgatgt cacgccgcgc
     7681 tatctggctc gtttgaccaa agaagagcag gagagcgagc aaaagtggcg taccgtcggt
     7741 accatccgcc gttacattct gttgatcctg acgctcgcgc aaactgtcgt cgcgacctgg
     7801 tatatgaaga ccattcttcc ttatcagggt tgggcgctga ttaatcctat ggatatggtt
     7861 ggtcaggatt tgtgggtttc ctttatgcag cttctgcctt atatgctgca aaccggtatc
     7921 ctgatcctct ttgcggtact gttctgttgg gtgtccgccg gattctggac ggcgttaatg
     7981 ggcttcctgc aactgcttat tggtcgcgat aaatacagta tatctgcgtc aacagttggc
     8041 gatgaaccat taaacccgga gcatcgcacg gcgttgatca tgcctatctg taacgaagac
     8101 gtgaaccgtg tttttgctgg cctgcgtgca acgtgggaat cagtaaaagc caccgggaat
     8161 gccaaacact ttgatgtcta cattcttagt gacagttata acccggatat ctgcgtcgca
     8221 gagcaaaaag cctggatgga gcttatcgct gaagtcggtg gcgaaggtca gattttctat
     8281 cgccgccgcc gtcgccgcgt gaagcgtaaa agcggtaata tcgatgactt ctgccgtcgc
     8341 tggggcagcc agtacagcta catggtggtg ctggatgctg actcggtaat gaccggtgat
     8401 tgtttgtgcg ggctggtgcg cctgatggaa gccaacccga acgccgggat cattcagtcg
     8461 tcgccgaaag cgtccggtat ggatacgctg tatgcgcgct gtcagcagtt cgcgacccgc
     8521 gtgtatgggc cactgtttac agccggtttg cacttctggc aacttggcga gtcgcactac
     8581 tggggacata acgcgattat ccgcgtgaaa ccgtttatcg agcactgcgc actggctccg
     8641 ctgccgggcg aaggttcctt tgccggttca atcctgtcac atgacttcgt ggaagcggcg
     8701 ttgatgcgcc gtgcaggttg gggggtctgg attgcttacg atctcccggg ttcttatgaa
     8761 gaattgccgc ctaacttgct tgatgagcta aaacgtgacc gccgatggtg ccacggtaac
     8821 ctgatgaact tccgtctgtt cctggtgaag ggtatgcacc cggttcaccg tgcggtgttc
     8881 ctgacgggcg tgatgtctta tctctccgct ccgctgtggt ttatgttcct cgcgctctct
     8941 actgcattgc aggtagtgca tgcgttgacc gaaccgcaat acttcctgca accacggcag
     9001 ttgttcccag tgtggccgca gtggcgtcct gagctggcga ttgcactttt tgcttcgacc
     9061 atggtgctgt tgttcctgcc gaagttattg agcattttgc ttatctggtg caaaggaacg
     9121 aaagaatacg gcggcttctg gcgcgttaca ttatcgttgc tgctggaagt gcttttttcc
     9181 gtgctgctgg ctccggtacg catgctgttc catacggtct tcgttgtcag cgcgttcctt
     9241 ggctgggaag tggtgtggaa ttcaccgcag cgtgatgatg actccacttc ctggggtgaa
     9301 gcgttcaaac gccacggctc acagctgctg ttagggttag tgtgggctgt tgggatggcg
     9361 tggctggatc tgcgtttcct gttctggctg gcaccgattg tcttctcgtt gatcctgtca
     9421 ccgtttgttt cggtgatttc cagccgtgcc accgttggtc tgcgcaccaa acgctggaaa
     9481 ctgttcctga tcccggaaga gtattcgccg ccgcaggtgc tggttgatac cgatcggttc
     9541 cttgagatga atcgtcaacg ctcccttgat gatggcttta tgcacgcagt gtttaacccg
     9601 tcatttaacg ctctggcaac cgcaatggcg accgcgcgtc accgcgccag taaggtgctg
     9661 gaaatcgccc gtgaccgcca cgttgaacag gcgctgaacg agacgccaga gaagctgaat
     9721 cgcgatcgtc gcctggtgct gctaagcgat ccggtgacga tggcccgtct gcatttccgt
     9781 gtctggaatt ccccggagag atattcttca tgggtgagtt attacgaagg gataaagctc
     9841 aatccactgg cattgcgtaa accggatgcg gcttcgcaat aaaaacgtag ttgcctgatg
     9901 cgctacgctt atcaggccta catcgttcct gcaatttatt gattttgcaa gactttgtgg
     9961 gtcggataag gcgttcacgc cgcatccggc aaaaacaacg agccaataaa aataccggcg
    10021 ttatgccggt atttttttac gaaagaggta tcaaatgcgt ttaattgtgg tgagcatcat
    10081 ggtgaccttg ctgagtggct gtggcagcat tattagtcgc actataccgg ggcaggggca
    10141 tggcaaccaa tattatcccg gtgtgcaatg ggatgtgcgt gactccgcct ggcgttatgt
    10201 cacgatcctt gatctgccat tctctctggt ttttgatact ttactgctgc cgatcgacat
    10261 tcatcatggc ccgtatgagt gattaacgtt catcccactc atcagctgct gcgcgtcctt
    10321 cctcggtatc cagcggtggc tcaagctgaa attccccctc gtcccattca tgtaatgtat
    10381 tctcttcctg ccactcctgg cgtatctcta tctcatcata gtcgccatca aaaacacttt
    10441 gcgcggcttc accgctaagc ataggtaaac attcaccttc ttccccttcg tcggcaaaaa
    10501 actcaacttg ccacatgatg tcgccgtcct gcaaaacgta tttttgggca ttgaactgtt
    10561 gcacattcgc atcttcggcg tcgatgccgg ggttgtctgc aagaaattct tcgcgtgcag
    10621 cgtcaatggc ttcttcaagc gttgcgtaca tggtcatcac gattctccct ttgagttgat
    10681 gaggtttcag ggaaaaggat agctgattct ccgcttttgc aagtatgaaa ggcgaaaaat
    10741 cagttcgata cctggggtat tcgacgacga cgtagactgt tccatgaata gactgcgttg
    10801 aataacacta cgccagcggt gacgagaaat accgctctga aaccgtagtt cgctgaaatc
    10861 gctgctccca tcaatggtcc ggtaacgttg ccaatatcac gaaacgattg gttatagctg
    10921 aagatacgcc cggcgatctg gttgctcgag ttgtaaacca acagtgtctg tacggcgggg
    10981 agtagtgcac catcggcggc accgagcaaa aaacgtaaaa tcccaagttg caatggcgtc
    11041 tgaacgtaag acattgggat caacagcagt acagaaaaga tcagcgctgt aatcaggatc
    11101 ttttcgggtc cgattcgatc gccaagtttg ccgagtcgtg gtgcacttag cagagccgcc
    11161 acgcctggca ccgaggcgat catgccactg ataaaggcga cgttactgac gttacccgcc
    11221 agttcgcgga catacagcgt cagaatgggg gcaattgagc ccgtcgccac ctggatgatt
    11281 aacgtagtga caaacaggct gagtaccagt ttcgggtttt taagtgatgt caccacttcc
    11341 cgcatgtgca gcatctcttt tttgctgacc ggctggaatt tttctctgat gcaaaacagg
    11401 gtgacgaaaa agcagagtat gagcacactg gcggtaataa agaataccgg acgtaagccg
    11461 tagctatcgg cgagcaggcc gccagccatt gggccgagca acgcaccact aacgccgcct
    11521 gtggagagcg tacccagcgc ccagccgctt ttattacgcg gtacttgtgt ggcgataaga
    11581 gcattagcgt tggggacaaa tccgccaagt aacccaagaa gcgcccgcag gatcaaaaac
    11641 tgccagatat tttgtgccag ccccatcaac accatcacga tgcccatgcc gagggcagag
    11701 cgtaatagca tgagttttcg gcctttacgg tcggcgagtc caccccaaaa cggtgaggcg
    11761 atggccgaaa ataaaaatgt aatgctgaag acaataccgg accacatatt cagggcggag
    11821 tgaccggtaa cgccaagctg ctcaacgtag aggggtaaga agggcattac cagactgaag
    11881 gcggcaccgg taagaaaaca gcctagccag gcgacgatca ggtttcgttt ccagtttata
    11941 ggggtgtcat tttcacaggg tgacatagca atccgctgtt ggtgcgccag gcgcggtgaa
    12001 cataagaaga aaagataagc acactaatta tgcgcccgac ttccaggggg cgcaatccag
    12061 agagctttta tcgctaaatc agggggattt gctgtggtaa tgccggatgc cattctgaag
    12121 catccggcat gggagattta atagcgtgaa ggaacgcctt ccgggcgtgt tttaaagcga
    12181 cggtgtaacc acatatactg ctctggtgcc atcatgatgc atttttcgac cactttgttc
    12241 atccacgcgg cggtagtttc ggcatcatcc agtggcggag aacactctgg cggcagcata
    12301 atcaattgat accctttgcc atctggctta cggcgtggaa cgaagggcac cagacatgcg
    12361 ccggacatcc gtgccagcat ccaggttccg gtcgtggtcg cagcctgctc aacggcaaac
    12421 aacgggacga aaacgcttga gcgcgggccg taatcatgat ccggtgcgta ccagaccact
    12481 tcgccttttt tcagggcttt aatcatgcct tttaaatctt tgcggtcgag catcgattta
    12541 tttgagcgca aacggcccca ggtttgtagc cagtcaatca gtggattatc gttcgggcga
    12601 taaacgccaa tacccggttc ctgcatacca aactgccgcg cacccagctc cagtgtcaga
    12661 aaatggatgc caactaacag gatgccgcgt ttttgcgcct gcacgtcacg aatgtgttcc
    12721 atgccgatca cttccgtcca gcgggcgatt cggcggtccg gccagaacca cgccatgccg
    12781 gtttccatca ggcccatgcc aacggattcg aaattcttca ccaccatttt acggcgttct
    12841 tgttcgctca tttccgggaa gcacagttcc aggttgcgat gcacaatttt tgcgcgtcgt
    12901 ttcataaaac gtaacgccag ttttcctaat ccacaaccga ggcggtagat aaccgggtag
    12961 ggcaattgca cgactaacca aagtacgcca atacccaacc aggttaacca ataacgcgga
    13021 tgaagcagtg cggtggagaa cttgggtaga ttcgtcatat caatcctgtt tttcaaccta
    13081 ttcgggcaat tgtatgtatt gtcgcatttt ttcgcccgca accaaaattt gtggctgaag
    13141 actgggcgaa attgccgcgc ttgtaaataa caaataattt ttaatgcgca aatgtagcgt
    13201 aaaatgtgtg gatgttaatt atcgataatt gctatatcat gccgcggatt tttactttcc
    13261 catctcgcag gaaccgtaca ccatgccagt gttacacaac cgcatttcca acgacgcgct
    13321 aaaagccaaa atgttggctg agagcgaacc gcgaaccacc atttcgtttt acaagtattt
    13381 ccacatcgcc gatcctaagg cgacccgtga cgctttatat cagctgttta ccgcgctgaa
    13441 tgtttttggg cgagtgtatc tggcgcatga gggcattaac gcgcaaatca gcgtacctgc
    13501 gagcaatgtt gaaacatttc gcgcgcagct ctatgccttc gacccggctt tagagggttt
    13561 acgcctgaat atcgcgttgg atgatgacgg gaaatccttc tgggtactgc gcatgaaggt
    13621 acgcgatcgc attgttgccg acggtattga cgatcctcac tttgatgcca gcaatgttgg
    13681 tgagtatctg caagcggcgg aagtgaacgc catgcttgac gatcccgatg cactatttat
    13741 cgacatgcgt aaccactatg agtatgaagt ggggcacttt gaaaacgcgc tcgaaattcc
    13801 ggcagatacc ttccgtgagc agctgccaaa agcagtcgag atgatgcagg cacataaaga
    13861 taaaaaaatc gtcatgtact gcaccggcgg cattcgttgt gaaaaggcca gtgcctggat
    13921 gaaacataac ggattcaaca aagtctggca tatcgagggc ggaattattg aatacgcccg
    13981 taaggcgcgc gagcagggct tgccggtgcg ttttattggc aaaaattttg tttttgacga
    14041 gcggatgggc gaacgtatat cggatgagat tatcgcgcat tgccaccagt gcggcgcgcc
    14101 gtgcgacagc cataccaact gtaaaaatga tggctgccac ctgctgttta ttcagtgtcc
    14161 agtatgcgcg gaaaaataca aaggttgttg tagtgagatt tgctgcgaag aaagcgcgtt
    14221 accgccagaa gaacagcgac gccgtcgggc aggacgtgaa aatggcaata agatctttaa
    14281 taagtctcgt ggacgtctga atacaacact gtgcattcct gatccaacag aataaatatc
    14341 attgccggat gcgtgccatc cggcaacatt tcacgcttac ttctgctgta cgccttccac
    14401 tgaaataatc agatccactt cctgagaagc tggacctaaa tctgtcttga tattgaagtc
    14461 cttgagctta attttgcctt cggcctcgaa gcctgcacgt ttaccacccc atgggtcgtc
    14521 gccctgacca attaatttcg cttccagcgt gacgggtttg gttacgccat tcagcgtcag
    14581 atcgccggta atatccagtt cgtcaccgtc tttcttcacg ctggtggagg tgaatgttgc
    14641 ctgtggatat tttgcggtat tgaggaaatc tgcactgcga agatgtttat cgcgttcggc
    14701 gtgattagta tcgacgctgg tggtgttaat tgtcacattc actttatcgg cagccggatt
    14761 tttttcgtca aaggtaaaag taccgtcgaa atctttaaag gtgccgtata accagctata
    14821 gccaaggtgc tggatgcgga aattaacaaa ggcgtgctga ccttctttgt caattttgta
    14881 atcggcggca accgctgaac cggcagagaa catcagggac gcgaaggtta aaccaagcag
    14941 gctttttttc attttttata ctccatagtc agatgacgac tttcccagca tgcgcttcag
    15001 agtgtcgtct ttatcgatga aatgatgctt cagggccata aatccgtgca taacggacag
    15061 tactacgacg ctccacgcga gccaaaaatg cagggcaccg gcaaagtctg cctgtgcgcc
    15121 agcgtcggca agggtcgcgg ggacgtcaaa ccagccaaaa acgctgatcg gtttaccatc
    15181 ggcagttgag atcagatagc cgctgatgcc gatggcgaaa agcaataggt acaatgcgag
    15241 atgtccagct cttgcggcaa gacgagtcat gggcgaataa ctcggcagcg gacccggcgg
    15301 tggagatatg acacgccaca gaacgcgaat agccagcccc atcattaaca aaataccgat
    15361 gcttttatgc agttcgggtg ctttgtgata ccagccatcg taataactga gcgtgaccat
    15421 ccacagacct aaagcaaaca tgccgtagac aataattgcg cttagccaat ggaaggccgc
    15481 agatataaca ccatagcgtt caggggtatt tgtgaatgac ataagtgcat ccaaaacgaa
    15541 tttgcgagag aaagaaaatg gcgtgtcgga gaatgaattg caacacaaaa ataacaaatt
    15601 gaatgatatt tatttttatt tcaataattt tgaattaata atgaaagaat cttcataagt
    15661 ttagtgggtt cagcatcaga gatgtctggt gagtgctgta gaagcaggaa taatctcatt
    15721 caatttttca cgctaaatga aagggagatt aaatatttgt cagtttatgt cagtgcggaa
    15781 aactaaaaat aaaacacata gatcagatcc ataattgcca acaatcccca gagaaaaaga
    15841 taaagcatca gatgctcgcg aatattattg atgagatagt gcaacagccg acgcattaaa
    15901 tactcctgta aaaacggcct cattctggag gccgtaatga tgattattgg aagcgggaaa
    15961 gcctgaatgg cgtcaaatca aaatcgcttt ttttgtcttg cgcaaaatcg gcagctattt
    16021 cccctaaaac tgacgcaaat ttaaaaccgt gcccactcag gccggtaatg agcagtgtat
    16081 tatcgtggcc gggtagggta tcgataataa aatcttcgtc aggcgaatta tcataggtgc
    16141 aggcagcgcc gtacaggcag caaccgatac ccggcaatac attgcgcaag aacgggaagg
    16201 cttttgaccc atcactggcc acttccgcaa acggaacacg ttcatccgct gaatggataa
    16261 cctggcctcc gttatgtttg ccaatcttca acgcgtcgtt ttctgccgga aaaccataat
    16321 attgatcgcc attgggcagt tcaccggtaa acgccgggaa tttattcttc acgctatagc
    16381 ggccatcggc ctgataccag gcaaatactt tgcgtacggg ctggacaggc agctccggga
    16441 gcaggtcttt tacccatgtt cccgcgcaga caatcgcttt tttcgcctga tactcaccgt
    16501 cagccgtttc aatagttacg ccatcatcgt catgacgaat tgcggtgacc gggcagttga
    16561 acagttgcgc acagcccgct tccttcgcca gttggatcca ggttttaatc gccagttcgc
    16621 tgcgcaaaaa accggaatca gtttcaaata agccgatgta gttgtccggg acgcgtattt
    16681 ccggccagcg ggccataatc ccttgcgcat cgagcttttc aacgttgagt tgccattgtt
    16741 cggcgctgtg ggcgacgttg gcgagaaatg tggaatcagc cgggccaagg ttaatgacgc
    16801 cagagcgtac aaaaatggga tcttcttcgt tgtggcggga gagttcatcc cacagcgttt
    16861 gcgcgcggag gaccagcggg acatactttt cgccttcacc ataagcatgg cgaattaatc
    16921 gcgtatcgcc gtggtggctg ccgtgttgat gcggtggcat atgggcgtcg gtcattagca
    16981 cgtttaaacc ggcgcgggtt gcataatacc cggcggcagc gcctacggaa ccgctgccaa
    17041 taatgatgag atcgtatttc atttttttct ctctgctctc atggtttaag cagagtaatt
    17101 aactgaatgc agatatacaa cccagaaatg gtaaaggcac cggtgaggtg ccttttgggt
    17161 ggatggtcat gtcatgttaa tgacgccgat actcgtttac ctggaaatca ccggattcaa
    17221 ttttggcgat tcctgcttct aatatcgaaa taaattgtct ggcaacatca gtggttaacc
    17281 agagcgtctg accaacttca gtcccttcct gctcggactt atttggggtc tggtagtgca
    17341 aacgcaacat cagcgcatca tagctatcaa cggtgctgat gtcccaccct acgagcggat
    17401 gagtctgaat gacttcatta tttttttcca tcatggcccc ctaattcgtg ttactagaca
    17461 acgttattcg aggttcaatg cgtttttatc tgaagcaact tcagtatacc aataagtaag
    17521 ggtattcacc gaatttttaa agggggaaac agataaattt ctgcttttaa gatttatatg
    17581 aacaataaaa cagcatgtca ttcatatttt tttagcatat tgtgcaatta ttttgaggaa
    17641 gtgtagaaat tttgtactca aaattcgtaa gtaaaataaa aaagccgggg cgacccggca
    17701 aaaaaaaatc actgcatatt attcgctgac aaaccagtca tcggcgcttt cccacgtttc
    17761 ctggagaatt tcactaatgc gctgtttatc ttcttttgtc gcgccaataa ccgataaatt
    17821 attcgctgcg gcataacgta ccgatacgtg gccttcatta tcaggaaacg catactgaat
    17881 acggcgggaa agttcgccag ccagggcgtc aatagcccca gctggcaatg gagaagtttt
    17941 cgctatggtg acttcaattc gcataatagc cccctgttga atatactggt tatttataca
    18001 ggtaaaataa cctaatgaca acaggaagct acgattttta ttgtttaacg gaccagcgta
    18061 ccgtttcccc ggcgaggaat ggcaccagcg tgtcatcagt cagtgcgatg ctttcagcaa
    18121 cctgttgctc ttcacgtacc agttcgatga atgtgtcgtt gaccggcaac ccatagaact
    18181 gcgggccgtt tacagaacag aatgcttcaa agtgctgcaa agcattcatt tcttcaaaga
    18241 cggtagcgta actgcccagc gcggttgggg cgttgaagca gcccgcgcag ccgcaactgc
    18301 tctctttgcg atgacgtgca tgtggcgcag aatccgtacc gaggaatact cgattaaaac
    18361 cgctggcgac cagttcacgc aatgcctgtt ggtgaatatt acgtttgagg atgggtagac
    18421 aatacaggtg cggacgcacg cctccaacca gcatatggtt gcggttaaac atcagatgct
    18481 gcggagtgat ggtggcagcc agccgttcat ttccgtcacg gacatagtcg gcagcatctt
    18541 tggtggtgat gtgctcaaaa acgactttca gcgcagtcag gcgctggcgc agaggttcca
    18601 tcacgctttc tataaagcgc gcttcacgat caaaaatgtc gatatctgca tgtgtcactt
    18661 caccatgcac cagtagcggc ataccgattt tttccatgcg ctcaagtacc ggcatgattg
    18721 cgtcaattga cgtcacgccg tggctggagt tagtggttgc gtttgccggg taaagttttg
    18781 cagcggtgaa cacgccttcg ttaaatccgc gctccagctc attaggatcc agcgaatctg
    18841 ttaaataaca ggtcatcaat ggggtgaaat cgtgcccggc aggtacggcg tcaagaatac
    18901 gctggcgata cgccacggca gcctcaacgg tggtcacggg cggagccaga ttgggcatta
    18961 cgatagcccg tccataaatt tcgctggtat atggcacgac agtttttaac atgtcgccat
    19021 cgcggaggtg aaggtgccag tcgtctgggc ggcggatctt taatacctgg gatggtgcag
    19081 tcattaatct ctatgctccg gctgaaggga tgtttttgcc ggacacaaag gataagcgga
    19141 aacgttttcc tttgcacgaa aaataaaggg cgcgaatgcg ccctcgtgat taatcagtaa
    19201 atggaatgac aatttcgcct ggcttcactt caatgccttt cgccagtttt ttcgccattg
    19261 cttcgccctg gctgccatct tcgcgcagga cgtaagcagg ttgctggtta aagtaattgc
    19321 gtaatgcctg gttcaaatag ggaagcaacg tttgcatcac cgtttgcatt ttttccggtt
    19381 gtaccgtcgc atcgaccact tccatctctt tcaggaagat cgcacctttt tctttatcaa
    19441 acacgggcag cgctttcagc ttcagtttca tggtcgcttt ctgactaccg aacagggagt
    19501 tcatgtccag attggcgtct ccggttaggg taaccttatt cggctcttcg cgaccaattt
    19561 ggctggtcag gtttgtcaga acaatatggg cgtcagccac gccgggtaaa ccgatatctt
    19621 ttgagaaatt attatgtttc gcaagcgact ggttaatttc ttgttcggtg atggtgtatt
    19681 gggtgagttg attacagcca acgagcaggc cactgacgat caatgcagcg gcaaataaaa
    19741 acttgttcat ggtagtcctc gacatgaaat ctgcgtcaat atcctgacac aacgcagcat
    19801 gtgtcaccag cgataaactc gccagcagaa aaaactgaaa acggcggcaa cccgcgaata
    19861 caggctgccg cggcgggtca ggattaaatc gccattgatg ataacaaatt gatttgtgtc
    19921 tgtttcgcca tattatcgcg gtaatcagca acgcggcttg gccagttaat tccggctacc
    19981 agcgtcagat tacgcagtag cgggaatagc tgaatatcat cttccgaaag ttcgccattc
    20041 acggcgttcg gtttgacgat cagtttgtcc agcgcacgta aatcatcgct gatattctta
    20101 atcagaccgt cagagtgggc cagcaggtcg gcaaaattac ccgcgctggc ctctttcttg
    20161 tcgacgaaat atttgcgcgc ggcgggagta gaaaactcat caaatgccga tttggcaaaa
    20221 cgcggcaaca gcagtttgtt ggcgtagcca ttgaccttgc gcagccactc ttcaatggca
    20281 ggggaacgtt tgccggtcag taacggtttg ccgtcgagtt tatcgacata gtgaacgatg
    20341 tccatgcttt ctggcatata gcggctgtca tctttttgca gaatgggaac ctgtttttga
    20401 ccgaccatcc gggtgggtgt ttctgcgtcg tcgttgagca gaacatgtaa ttcgacgggg
    20461 atatttttca ggccgaaaat catgcgggct ttgaggcagt aagggcagtg atcgtaaatg
    20521 tatagcttca cgtgactcct ccatttggct gtcagttcac tttcagtatg aaggagtcag
    20581 gggggagtat caaatcaggc gtcgcgttca agcaaacgac gcgcggcgcg tttctggcta
    20641 aactgccaac ccagcgcaag gaaagtgaag atgccaataa tgcccagcat catccacgga
    20701 agctctggct ggtgcgccga tttgcccagg tcaaacagcc agccgccacc gatataacca
    20761 atagcgccgc caatcgccag acccagacgg ctaaacccca tatagctgcc gcgagctctt
    20821 gcgtccgcca gcgaagcact taaggtttca cgcgcaggct cggcaatgat cgacccgata
    20881 taaaacagac aaatcagggt gaaaagttgt tgcaggccgc tgaccatgcc caccggcatc
    20941 atgcttaatg acattatcaa cagcccagcc atcaaccggt gttccagacg aaaatgcttt
    21001 tcactccagc gggcgatagg gtagagcaac gttaacgaca gacacgcttc aatggcatac
    21061 atccatttaa cggcagaggg cgcgccagcc acgtcgttga ccataattgg cagcatcagc
    21121 atcacttgta cagccagcat gtagtaaccc gccagcgtca gaacataggt gacaaaacgc
    21181 ttgtcacgca tcacgcgggt catgccttcg cgaacgggcg tgcgtacggt ggagagtttc
    21241 catgctggta acaaccacgc attgaacgcc gcacatagca caaatagaac tgcccctgtg
    21301 gcgcagacca ggcgaaagtc gtattgcaac agccagctcc ccaacaatgc gccaatgacc
    21361 gcaccggcac tgtcctgcat catcaacagc gagaaaaaac gaccacgctg ctgtggacgg
    21421 attaatttca ccaccagcgc cgaacgcggc ggatcaaaca acgtgccacc gagtcccgag
    21481 agcaggcatg aaaaccacaa tagccacggt tcgtgggcga tacccattgt ggcgaatccg
    21541 gcggcgcgca tcagcatacc ggtaacaatc atcggtttgg caccaaagcg gtcggcaatt
    21601 gcaccgccga aaatacccag accttgctga ataaattggc gtagaccgag agcaataccg
    21661 accatgacgg cggcccagcc catttgatca acgaagcgga tagagatcag cgggaagaca
    21721 acaaagaacc ccagcacgac cagcatatta tcgatgagca ggaaatattt acccaggttc
    21781 ctcgcctgcg acacgcggga catttcccct cccgggaaat aaaagatgag cactttctat
    21841 tctgcattgc cgctaagact tttcccatca cttcggggac aatatttttt tatcaaaacg
    21901 tcgctttgat agagagtttt tatcaaatat gtgaataatg cagaaaatgg cattttggac
    21961 ttttcacagg gtctggttgc gcaggtatag taatacttac agcgtattaa agacgttacg
    22021 ggaaggagta ggtatagaat gtttggctat cgcagtaacg tgccaaaagt gcgcttaacc
    22081 acagaccgac tggtcgtgcg tctggtgcat gatcgtgatg cctggcgtct tgcggattat
    22141 tacgcagaga atcgccattt cctcaagccc tgggagccag tgcgcgacga aagccactgt
    22201 tatccatcag gctggcaggc caggctgggg atgattaacg aatttcataa acaaggttca
    22261 gctttctact ttggcttatt cgacccggac gaaaaagaga ttattggcgt tgccaatttt
    22321 tccaatgttg ttcgtggctc ttttcatgcc tgctatctcg gttattcgat tgggcaaaaa
    22381 tggcagggca aaggactcat gtttgaagcc ctgaccgcag ccattcgtta tatgcagcgc
    22441 acccaacata ttcatcgcat tatggctaat tatatgccgc acaataaacg cagcggtgat
    22501 ttactggcgc gactgggttt tgaaaaagaa ggctatgcga aagactatct gttgattgat
    22561 ggacaatggc gcgatcacgt actgacggca ttaactaccc cagactggac gcccggccgc
    22621 taaggagaat ctcatgaaat atcaacttac tgcccttgaa gctcgcgtga ttggttgctt
    22681 gctggaaaag caggtgacca cgccggagca atacccgctc tcagtcaatg gtgtagtcac
    22741 ggcctgtaat cagaaaacga accgtgaacc ggtcatgaat ctgagtgaat ccgaagtgca
    22801 ggaacagctg gataatctgg tcaaacgtca ttatctacgc acagtgagcg gttttggtaa
    22861 tcgggtcacc aaatatgagc aacgtttttg taattcagaa tttggcgatc tgaaactgag
    22921 cgcagcggaa gtggcgttaa tcaccacgtt gttattgcgt ggtgcccaga cgccaggtga
    22981 actgcgcagc cgcgccgcgc gaatgtatga attcagcgat atggcggaag tggagtcgac
    23041 gctggaacaa ctggcaaatc gcgaagatgg tccttttgtg gtgcgtctgg cccgcgaacc
    23101 gggtaaacgc gaaaaccgct acatgcatct tttcagtggt gaggttgaag atcagccggc
    23161 ggtgacggat atgtcgaacg cggttgacgg tgatttacag gcccgcgtcg aagccctgga
    23221 aatcgaagtg gcagaactga aacagcgtct tgattcgttg ctggcccatc tgggagatta
    23281 aagtgaaaaa aatacgtatc ggcgtagtgg gattaggtgg cattgcgcaa aaagcgtggt
    23341 taccggtgct ggcggcagcg tctgactgga cgttacaagg agcctggtcg cctacgcgcg
    23401 cgaaagccct gccaatttgt gaaagctggc gcattcctta tgccgattcg ttatccagcc
    23461 ttgccgccag ttgcgatgcg gtttttgtgc attccagcac cgccagccac tttgacgtgg
    23521 tcagtacgtt actcaatgcg ggggtacatg tctgtgtcga taaaccgctg gcagaaaatc
    23581 tgcgcgatgc tgaacggctg gtggaactgg cggcgcggaa aaaactgacg ttgatggtcg
    23641 gttttaaccg tcgtttcgca ccactctacg gtgagttaaa aacgcaactc gccaccgcag
    23701 cctcgctaag aatggataaa catcgtagca atagcgtcgg gccacacgat ctttatttca
    23761 cgttgctgga tgattatctg catgtggtgg ataccgcgct gtggttgtcg ggcggcaaag
    23821 cctctctgga tggcggtacg ctactgacta acgacgctgg cgaaatgctg tttgccgagc
    23881 accatttttc ggctggtcct ttgcagatca ccacctgtat gcatcgccgt gccggaagtc
    23941 agcgtgaaac cgtgcaggcc gtgactgacg gtgcgctcat cgacattacg gatatgcgcg
    24001 aatggcgtga ggagcgcggg cagggcgtag tgcataaacc gattcctggt tggcagagta
    24061 cgcttgagca acgtgggttt gtcggctgtg cgcggcactt cattgaatgt gtgcaaaacc
    24121 agacagttcc gcaaaccgcc ggcgaacagg ccgtgctggc gcaacgtatc gttgacaaga
    24181 tctggcgcga tgcgatgagt gaataaaccc tgtaacatct ggcggtagca attcaccata
    24241 atccaggtag actattcgcc tctttcagcg cctgccttgc aggcgttttg cccgtgggtc
    24301 tggattagaa caccgatgaa tttattaaaa tcgctggccg ccgtcagctc gatgaccatg
    24361 ttttcgcgtg tgcttggctt cgcacgagac gcaattgtcg ccagaatctt tggcgcaggg
    24421 atggcaaccg acgccttttt cgtcgctttt aaacttccta acttgttacg ccgtatcttt
    24481 gccgaagggg cattttccca ggcatttgta ccgattctgg cggaatataa aagtaagcag
    24541 ggtgaagacg ccacgcgggt ctttgtctct tatgtttctg gcctgctgac acttgcgctg
    24601 gcggttgtga cggtcgctgg catgctcgcc gcaccgtggg tgatcatggt gaccgcgcca
    24661 ggcttcgctg acacagctga caaatttgcc ctgaccagcc agctactaaa gattaccttt
    24721 ccctatatct tgctgatctc cctggcgtcg ctggtgggag cgattctgaa tacgtggaac
    24781 cgcttctcga ttccggcgtt tgctccaaca ctgcttaaca tcagcatgat tggtttcgcg
    24841 ctgtttgccg caccgtactt taacccaccg gtgctggcgc tggcgtgggc tgttacggtc
    24901 ggcggcgtcc tgcagctggt gtatcagcta ccgcacctga agaagatcgg catgctggtc
    24961 ctgccgcgca ttaacttcca cgatgccgga gcaatgcgcg tggtgaaaca gatgggaccg
    25021 gcgatccttg gcgtctctgt gagccagatc tccttaatca tcaacaccat ttttgcctcg
    25081 tttcttgctt ccggttcggt gtcttggatg tattacgccg accgcttaat ggagtttccg
    25141 tccggtgtgc tgggcgtggc gcttggcacc attttgctgc cgtcgctgtc gaaaagtttt
    25201 gccagtggca atcatgatga atacaaccgt ttgatggact gggggttgcg tctttgtttc
    25261 ctgttggcgc tgccgagtgc ggttgcgttg ggcattcttt ccggtccgtt gaccgtttcg
    25321 ctgttccagt acggtaaatt taccgcgttt gatgcgctga tgacccagcg ggcgttaatt
    25381 gcctactcgg tgggtttgat tggcctgatt gtagtgaaag tgttggctcc tggcttttat
    25441 tcccgccagg acattaaaac gccagtgaaa attgccatcg ttacgctgat tttaacgcaa
    25501 ttgatgaacc tggcgtttat tggtccgttg aaacatgccg ggctgtcact ttctattggt
    25561 ctggcggcgt gtctgaatgc ttcgctgctt tactggcagt tgcgtaagca gaaaatcttt
    25621 accccgcaac ccggctggat ggcgtttctg ttgcgtctgg tggtggcggt actggtgatg
    25681 tctggcgtgc ttttaggtat gttacatatc atgccggagt ggtcattggg taccatgccc
    25741 tggcgtttac tgcgtttaat ggcggtcgtg ctggcgggga ttgccgcgta cttcgctgca
    25801 ctggcggtac tgggcttcaa agttaaagaa tttgcccgcc ggacggtgta acaatgcatt
    25861 ccggcctgca gtgcaggccg gagataatct tcagatcgaa atctttttac cgccgcgatg
    25921 ggttgttgag gtctgaccgt tcgccccata tagcgtcggt tcctgatgcg gtttcaacat
    25981 ttccagcgcc tgttgattgc gctcaatctg tccttccagt aaccagccgt tatgttgatt
    26041 catttggcgt agttgctgcg ttttcacagt aatttcctgc cagcgttgac taatatcaac
    26101 gctatttgct gtattgggtt ctttcctgcg taactgttcg aggtaatcca gcgtcgccag
    26161 cagtgagctt ttttgttctg taatccattg caactggctg ccgttgatct gccccataga
    26221 gagatgttgc tgctcttgat ccattaccgt tttgagatcg ttaagcacag cggacatctg
    26281 gtcgaggatc tctgcaagac gtgtcatacg atcagttact ctgcaagtct tgctgcgctt
    26341 cgttgatcag cgcatcggca attttgccgg tgtccatttt tagttcaccg ttacgaatcg
    26401 ccagttttaa cgcttcgaca cgttcaagat tgatatcact gctgccgggt tgcatcagtt
    26461 ttgcttgcgc gtcgcttaac gtcacactgg tgctggtgga ggcggttgtt tttgccgccc
    26521 ggctgttcgt taccggcgcg tcagtggttt cgcgcggttg aacggtgctt acaggcttca
    26581 gaggcgaagt gcgatcaata ctcatggttt attcctcatt gagggcgctt ttatcatgtg
    26641 ttgcttattt atcggcaagg gacgggtaat ctttaacagc ttacaggttt ataagaatat
    26701 tcccatctgc atcaacaacg ccgctgacta cctgtcccga taccatgcgc acccgcgcat
    26761 tctgtgcgac ggctgcattg ttcagcgcct gaccttctgc gttggcgcta aacccatcac
    26821 cgctggcgat cacattgacg cgttgtcccg cttttacccg ccatgcctgg cgaaactggg
    26881 ttaactggat aggttgatcg ggtgatagat cgcgcaggct aatggcatca acaagttgat
    26941 tgatatccag caccgtacgc ggtggcaggg tatccagccg tccgcgtttc agtttgacat
    27001 tgccagcttc cagctttcct ccccgcgcaa tgggcatcgc ggcaaccaca taatttcctg
    27061 tggcctgtac attaacctgt aaatatcgtt tgtcgttacc gcagcgtgcc aacacattca
    27121 cattgcccca caggcgggaa ttattgctca tcgaaagcaa tggctgctcg catggcggta
    27181 gtagattggg cgctgtacga atagaaacac gaacctcatc acttaccccc gcgagttggg
    27241 cgctaaaaaa gttgtgcaat tgcgatgtga gattgctcgc cgtacttaac ggactgaaca
    27301 gtatcgcgat gatcgccacg ctacgtttta ttatcagcat tttcgccccc agccatttct
    27361 acaacgtgaa ttgtacctgt ccgcaatgac catcaacggc ataaatagcg acccattttg
    27421 cgtttattcc gccgataacg cgcgcgtaaa ggcatttaag ctgatggcag aattttgata
    27481 cctgcggagg agatatgctc gataagctcg acgccgcctt acgttttcaa caagaggcgc
    27541 tcaatctgcg cgcccagcgt caggaagtgc tggcagcaaa catcgccaat gccgataccc
    27601 ctggttatca ggcgcgcgat atcgattttg ccagtgaact taaaaaagtc atgcaacgtg
    27661 gacgggatgc aaccagtgtg gttgcactga cgatgacctc aacgcaacac attccggcgc
    27721 aggcgctgac gcctcctacc gcagaactgc aataccgtat tccggaccag ccttcgcttg
    27781 acggtaatac cgtcgatatg gatcgcgaac gcacccagtt tgccgataac agcctgcaat
    27841 accagatgag ccttagcgcg ttgagcgggc aaatcaaagg catgatgaac gttttacaga
    27901 gcggaaatta acggatggca ctgctgaata tttttgatat cgccgggtcg gcgttaactg
    27961 cccagtccca gcgcctgaac gtggcggcca gtaatctggc gaatgctgat agcgtgaccg
    28021 gtcccgatgg acagccatat cgggcaaaac aggtggtatt ccaggttaac gctgcaccag
    28081 gtgctgcgac aggcggcgta aaggttgccg atgttataga aagtcaggcc ccggacaaac
    28141 tggtttatga accgggtaat ccgctggcag atgcaaaggg ctacgtaaaa atgccgaacg
    28201 ttgatgttgt cggagagatg gttaacacca tgtcggcgtc acgcagctat caggccaatg
    28261 ttgaagtgct caacacggtg aaaagcatga tgctgaaaac ccttacgctc ggtcaataaa
    28321 ggagaaagct atgtccattg cggtaaccac caccgatccg acaaataccg gcgtcagtac
    28381 caccagcagt agttcgctca cgggcagcaa cgtcgcagat ttacaaagca gttttctgac
    28441 tttgctggtg gcgcagctga aaaaccagga cccgaccaat ccaatggaaa acaacgagct
    28501 gacgtcgcaa ttggcacaaa tcagcacggt cagcgggatt gaaaaactca ataccacgct
    28561 cggatctatt tccggacaga ttgataacag ccagtcgtta caggccagta acctgatcgg
    28621 tcacggcgtg atgatccccg gcaccactgt tcttgcggga accggcagtg aagaaggggc
    28681 tgtgaccacg accacgccgt ttggtgttga gctgcaacag gcggcagaca aagttacggc
    28741 caccatcacc gataaaaatg gcgcggttgt gcgcaccatt gatattggtg aactgaccgc
    28801 cggagttcac agtttcacct gggacggtac gttgactgat ggcagcactg cgccgaacgg
    28861 ttcttacaat gtagcgatta gcgccagtaa cggtggtaca caactggttg cccagccgct
    28921 gcagtttgct ctggtgcagg gtgtgatccg cggcaacagc ggtaatacgc tggatctcgg
    28981 cacttacggc accaccaccc tcgacgaagt acggcagata atttaagcct tcacatttca
    29041 ggagtcagtc atggcctttt ctcaagcggt tagcggatta aacgctgccg ccaccaacct
    29101 cgatgttatt ggcaacaata tcgccaactc cgccacctac ggctttaaat caggcacggc
    29161 ctcttttgcc gatatgtttg ccggttcgaa agtgggactg ggggtaaaag ttgccggtat
    29221 cactcaggac tttaccgatg gcacgaccac caacaccggg cgaggtctgg acgttgctat
    29281 cagccagaac ggttttttcc gtctggtaga cagcaacggt tcggtgttct acagccgtaa
    29341 cggacaattt aagctggatg aaaaccgtaa cctggtgaat atgcaaggtt tacagctgac
    29401 gggttacccg gcaaccggta cgccgccgac tattcagcaa ggggcgaatc cgaccaatat
    29461 ttcgatcccg aataccctga tggcagcgaa aactaccacc acggcatcga tgcagatcaa
    29521 cctgaattcc agtgatccgc ttcctactgt tacgccattc agcgccagca atgcggatag
    29581 ctataacaaa aaaggttcgg tgactgtttt cgacagtcag ggtaatgctc atgacatgag
    29641 cgtctacttt gtgaagaccg gggataataa ctggcaggtc tacacccagg atagcagtga
    29701 tccaaacagc attgcgaaga cagcgacaac actggaattt aatgctaatg gcacattagt
    29761 ggatggtgcg atggcgaata atatcgcaac cggcgcaatt aacggtgcag aacccgccac
    29821 gtttagtctg agcttcctca actccatgca gcaaaatacc ggcgctaaca atattgtggc
    29881 aaccacccag aacggctaca aaccgggcga tctggtgagt tatcaaatca atgatgacgg
    29941 tacggttgtc ggcaactatt ccaacgaaca aacccaactg ctggggcaga ttgtactggc
    30001 gaactttgcc aacaacgaag gtctggcatc cgaaggcgac aacgtctggt ctgcgacgca
    30061 atcttctggc gtggcgctgt tggggacagc cgggacggga aactttggca ccctgaccaa
    30121 cggtgcgctg gaagcgtcca acgtcgatct cagtaaagaa ctggtcaata tgatcgttgc
    30181 ccagcgtaac tatcagtcta acgcccagac catcaaaacc caggaccaga tcctcaacac
    30241 gctggttaac ttacgctaat cgctgacggg atagctcaat ggatcacgca atttataccg
    30301 cgatgggagc agccagccag acactgaatc aacaggcggt aaccgccagt aatctggcca
    30361 atgcctcaac gcccggtttt cgcgcgcagt tgaatgcttt acgcgcggtg ccagtggaag
    30421 ggctttctct gcctacgcgc acgttggtca cggcgtcaac gccgggcgca gatatgacgc
    30481 ccggcaaaat ggattacacc tcgcgcccgc tggacgtcgc gttgcagcag gatggctggc
    30541 tggccgtgca gaccgctgac ggcagcgaag ggtatacgcg taatggcagc attcaggttg
    30601 atcccaccgg gcaactgaca attcaggggc atccggtgat aggcgaggct gggccaattg
    30661 ctgtgccgga aggggcggaa atcactattg ctgccgatgg cacaatctcg gcgctcaatc
    30721 cgggcgatcc ggcaaatacg gttgcgccag tagggcgtct taaactggtg aaagccacgg
    30781 gcagcgaagt gcagcgcggt gacgacggca tttttcgttt aagcgcagaa acccaggcca
    30841 cgcgtgggcc ggtactgcag gcagatccaa ccttgcgtgt gatgtcgggg gttctggaag
    30901 gcagtaacgt caatgccgtt gcggcaatga gcgacatgat tgccagcgcg cggcgttttg
    30961 aaatgcagat gaaggtgatc agcagcgtcg atgataacgc aggccgtgcc aaccaactgc
    31021 tgtcgatgag ttaattgaaa ggatacatga caagtataag ttgcccgatg cgcaagttta
    31081 tcgggtctat gggggcaatc gcaatttatc gattttgcga gcacttgtag gccggataag
    31141 gcgtttacgc cgcatccggc aagaagacat atgcactttg tcactaatcc actacaggac
    31201 attttatgat cagttcatta tggatcgcca aaacgggcct tgacgcccag caaaccaata
    31261 tggacgtcat tgccaacaac ctggcaaacg tcagtactaa cggttttaag cgtcagcgcg
    31321 cggtgtttga agatctgctt tatcaaacca ttcgccagcc gggggcacag tcttccgaac
    31381 aaaccacctt accctccgga ttacaaatcg gcacgggggt acgcccggtc gccactgaac
    31441 gcttacacag ccagggaaac ctgtcgcaga ccaacaacag caaagatgtc gcgattaaag
    31501 ggcagggctt tttccaggtg atgttgccag atggttcatc agcctatacc cgtgacggct
    31561 ctttccaggt ggatcagaac gggcagctgg tgacggctgg tggttttcag gtgcagccag
    31621 cgatcaccat tccggcgaat gcgttaagta tcaccatcgg tcgtgatggc gtggtcagcg
    31681 taacccaaca aggccaggca gctccggttc aggttgggca gctcaatctc accaccttta
    31741 tgaatgacac cgggctggag agcattggcg aaaacctcta caccgaaacg caatcctctg
    31801 gtgcaccgaa cgaaagcacg ccgggcctga acggcgcggg actgctgtat caagggtatg
    31861 ttgaaacgtc taacgtcaac gtggcggaag aactggtcaa tatgattcag gtgcaacgcg
    31921 cttacgaaat caacagtaaa gcggtgtcca ccaccgatca gatgctgcaa aaactgacgc
    31981 aactctaagg cttaaccggt ggcaggttca ccggtttact gatttttgaa gatgatagcc
    32041 atgcaaaaaa acgctgcgca tacttatgcc atttccagct tgttggtgct ttcactaacc
    32101 ggctgcgcct ggataccctc cacgccgctg gtgcaggggg cgaccagtgc acaaccggtt
    32161 cccggtccga cgcccgtcgc caacggttct attttccagt ctgctcagcc gattaactat
    32221 ggctatcaac cgctgtttga agatcgtcga ccacgcaata ttggcgatac gctgaccatc
    32281 gtgttgcagg agaacgtcag cgccagcaaa agctcctctg cgaatgccag ccgtgacggt
    32341 aaaactaatt ttggctttga tactgtgccg cgctatttgc aggggctgtt tggtaacgct
    32401 cgtgccgatg tcgaagcctc cggtggtaac acgttcaacg gaaagggcgg ggccaatgcc
    32461 agcaatacct ttagcggcac gttgacggtg acggttgacc aggtactggt caacggcaac
    32521 ctgcatgtgg tgggtgaaaa acagattgcc attaatcagg gtaccgaatt tattcgcttc
    32581 tctggcgtgg ttaatccacg cactatcagc ggcagcaata ccgtaccgtc tactcaggtg
    32641 gcggatgcgc gcattgaata cgtaggcaat ggctacatta acgaagcgca aaatatgggc
    32701 tggttgcagc gtttcttcct taacctgtcg ccaatgtaag tgaggctgtg gtgattaaat
    32761 ttctctctgc attaattctt ctactggtca cgacggcggc tcaggctgag cgtattcgcg
    32821 atctcaccag tgttcagggg gtaaggcaaa actcactgat tggctatggt ctggtggtgg
    32881 ggctggatgg caccggtgac cagacaaccc agacgccgtt taccacacaa acgcttaata
    32941 acatgctctc acagctggga attaccgttc cgacgggcac caatatgcag ctaaaaaacg
    33001 tcgctgcggt aatggtgaca gcgtcacttc ctccgtttgg acgtcagggg caaaccatcg
    33061 atgtggtggt ttcttccatg ggaaatgcca aaagcttgcg tggaggtacg ttgttgatga
    33121 caccgcttaa gggcgttgac agtcaggtgt atgcgctggc gcagggcaat attctggttg
    33181 gcggcgcagg agcctccgct ggcggtagca gtgttcaggt taaccaactg aacggtggac
    33241 ggatcaccaa tggtgcggtt attgaacgtg aattgcccag ccagtttggc gtcgggaata
    33301 cccttaattt gcaacttaac gacgaagatt tcagcatggc gcagcaaatc gctgacacca
    33361 tcaaccgcgt gcgtggatat ggcagcgcca ccgcgttaga tgcgcggact attcaggtgc
    33421 gcgtaccgag tggcaacagt tcccaggtcc gcttccttgc cgatattcag aatatgcagg
    33481 ttaatgtcac cccgcaggac gctaaagtag tgattaactc gcgcaccggt tcggtggtga
    33541 tgaatcgcga agtgaccctc gacagctgcg cggtagcgca ggggaatctc tcagtaacag
    33601 ttaatcgtca ggccaatgtc agccagccag atacaccgtt tggtggtgga cagactgtgg
    33661 ttactccaca aacgcagatc gatttacgcc agagcggcgg ttcgctgcaa agcgtacgtt
    33721 ccagcgccag cctcaataac gtggtgcgcg cgctcaatgc gctgggcgct acgccgatgg
    33781 atctgatgtc catactgcaa tcaatgcaaa gtgcgggatg tctgcgggca aaactggaaa
    33841 tcatctgatg atcagcgaca gcaaactact ggcaagtgcg gcctgggatg cgcaatcact
    33901 caacgaacta aaggcgaaag cgggcgaaga tccggcggca aatatccgtc cggtggcccg
    33961 tcaggtggaa gggatgttcg tgcagatgat gttgaaaagc atgcgcgacg ctttaccaaa
    34021 agatggcctg ttcagcagcg agcacactcg cctgtatacc agtatgtatg accagcagat
    34081 tgcccaacag atgacggcgg gcaaaggtct ggggcttgca gagatgatgg ttaaacagat
    34141 gacgccagaa caaccattgc cagaggagtc cacgccagca gcaccgatga aattcccgct
    34201 cgaaactgtg gtgcgttatc aaaatcaggc gctttcgcag ctggtgcaaa aggccgtgcc
    34261 acgtaactac gatgattcgc tgccgggtga cagtaaagca ttcctcgcgc aactctcgct
    34321 gcccgcccaa ctggcaagcc agcaaagcgg tgtgccacat catttgatcc tcgctcaggc
    34381 ggcactggaa tctggttggg ggcaacggca aatccgccgc gaaaacggcg agccgagcta
    34441 taacctgttt ggtgtcaaag cctctggcaa ctggaaaggg ccagttactg aaatcaccac
    34501 gactgaatat gaaaacggcg aagcgaagaa agtaaaagcg aagtttcgcg tctacagctc
    34561 gtatctggaa gccttgtcgg attacgttgg gctgttaacg cgtaacccgc gctacgccgc
    34621 cgtgacgacc gccgcgagtg cggaacaggg ggcgcaggcc ctacaggacg cgggctatgc
    34681 caccgatcct cactatgccc gcaaactcac caacatgatt cagcagatga aatcgataag
    34741 cgacaaggtg agcaaaacct acagtatgaa cattgataat ctgttctgaa taactcaagt
    34801 ccggcgggtc gctgccgata atactctgta attgaaggct tataaggaac ctccatgtcc
    34861 agcttgatta ataacgccat gagcggactg aacgcggccc aggcggcgtt aaatacggca
    34921 agtaataata tctccagcta taacgttgcc ggatataccc gccaaaccac tattatggag
    34981 caggccaata gcacgttggg cgctggcggc tgggttggca atggtgtcta cgtttctggt
    35041 gtgcagcgtg agtatgatgc gtttattacc aaccagttac gtgcggcgca gacgcaaagt
    35101 agcggtctga ctgcccgcta tgagcagatg tcgaaaatcg acaatatgct ctccaccagt
    35161 acctcttcgc tggcaacaca gatgcaggat ttcttcacca gcctgcaaac gctggtgagt
    35221 aacgcggaag acccggcagc gcgccaggcg ctgattggga aatcagaagg attggtgaat
    35281 cagtttaaaa ccaccgatca atatctgcgc gaccaggaca aacaggtcaa tatcgcgata
    35341 ggtgccagcg ttgatcagat caacaactac gctaaacaaa ttgccagcct gaacgatcaa
    35401 atctcgcgcc tgacaggcgt gggggcaggg gcgtcaccta acaatctgct ggatcaacgc
    35461 gatcaactgg tgagcgaatt aaaccagatt gttggtgtag aagtcagcgt tcaggatggc
    35521 ggcacttata acatcacgat ggccaatggt tactcactgg ttcagggaag tacggcgcgg
    35581 caactggcgg cagttccttc cagcgctgac ccttctcgta cgactgtcgc ttatgttgat
    35641 gggacggcag gcaatattga gatcccggag aaattactga ataccgggtc gctgggcggc
    35701 attctgacat tccgttctca ggatctggac cagacgcgta atacgcttgg acaactggcg
    35761 ctggcatttg ccgaggcttt caacacccaa cacaaagccg gatttgatgc taacggcgat
    35821 gccggtgaag atttctttgc tatcggtaag cccgcggttc tgcaaaacac gaaaaacaaa
    35881 ggtgacgttg cgatcggtgc cacggtaact gatgcctccg cggtactggc gacagattac
    35941 aaaatctcgt tcgataataa tcagtggcag gtcacccgcc ttgccagcaa taccactttt
    36001 acggtgacgc cggatgccaa cggtaaagtg gcatttgatg gtctggagtt gacgtttaca
    36061 ggaacgcctg ccgttaacga cagcttcacg ctgaaaccag taagtgacgc catcgtcaac
    36121 atggatgtat taatcaccga cgaagcgaaa atagcgatgg cgagcgaaga agatgcgggt
    36181 gatagcgata accgcaacgg tcaggccctg ctggatctgc aaagcaacag taaaacggtg
    36241 ggcggtgcga aatcctttaa cgacgcttat gcctcgttag tgagtgatat cggtaataaa
    36301 accgcgacgt tgaaaaccag tagcgccacg caaggtaatg tggtgacgca gctttccaat
    36361 cagcagcagt cgatttccgg tgtcaatctc gatgaggagt acggaaatct gcaacgtttt
    36421 cagcagtatt acctggcgaa tgcgcaggtt ctgcagacgg caaacgcgat ttttgatgcg
    36481 ctgattaaca ttcgctaagg ggagataaga tgcgtttcag tacacagatg atgtaccagc
    36541 aaaacatgcg tggtatcacc aattctcagg cagaatggat gaagtacggc gaacagatgt
    36601 cgacgggtaa gcgagtcgtt aacccttctg acgatcccat tgctgcatca caagccgtag
    36661 ttctctccca ggcacaggcg caaaacagcc agtacacgct ggcgcgtact ttcgccactc
    36721 aaaaagtgtc actggaagag agtgtactta gccaggtcac cactgctatc cagaatgctc
    36781 aggaaaaaat tgtctacgcc agcaatggca ccttgagtga cgatgaccgg gcctcgctgg
    36841 ctacggatat tcaggggctt cgtgaccagt tgctgaatct ggcaaacacc actgacggta
    36901 acgggcgcta catttttgcc ggttataaaa cagagactgc gccgtttagc gaagagaaag
    36961 ggaaatacgt cggtggagca gaaagtatta aacaacaggt cgatgcttcg cgttcgatgg
    37021 tgatagggca cacgggtgac aaaattttcg acagtattac cagcaacgcg gtagcggaac
    37081 cagacggtag cgcttctgaa accaatcttt ttgccatgct ggatagtgcc atcgcagccc
    37141 tgaaaacgcc ggtcgcggat agcgaagcgg ataaagaaac cgccgctgcg gcgttagata
    37201 aaaccaaccg cggactgaaa aactcgctga acaatgtgct gactgttcgc gcggaattag
    37261 gcacgcagct gaacgaactg gagtcgctgg attcattagg tagcgatcgc gctttagggc
    37321 aaacgcagca gatgagcgat ctggttgatg tggactggaa tgcaactatt tcatcttaca
    37381 tcatgcagca aacggcattg caggcatcgt ataaagcatt taccgatatg cagggattgt
    37441 cgctcttcca gctcagcaaa taatttcgct ttaaaacata tcatgaaact gggtatgttt
    37501 tgtctgcctg ctctgggatc gctggggcgg gcattttttt gcctattttg cattgttggt
    37561 tagcaaggat gccattcgat gaattttaat atgttgattc aaagatgaaa taaaaaagcc
    37621 ctggcagtta ccagggcttg attactttga gctaattatt actcaacagg ttgcggacgc
    37681 gcaggagcgg cagaggcatg atgtgttgcc gtatgaccac ctgcggcacc tttaccttcg
    37741 aaggcaaaag tagggcgctg ccagtcactg tgacgcggtg cctccggaac atattccggt
    37801 gctggagcgc gcgtcattgg cgcggtagcg tggttatgct caacggtgac ctcaggttcg
    37861 accgcagcta ccgtttcaac ttctgctgcg acttcagcga ctactggcgc ggcaggttga
    37921 gcaacaactt caggttcagc aactacaacc tcagcagttt cgacaacttc ttcaatatct
    37981 gccgtctctt cctgcggttc aaccaccggt tctgcttgtt ctgcaacttt ctgggctacg
    38041 gcaacatcag actcggtaat cacctgcggc tgttcagtta ccgcggcagc gatcacttca
    38101 ggatgcgtcg tttcaaccac ttccggttgc ggttcggcaa cctgaacggg ggcttctacg
    38161 acaccggcca cttcttcaac aactggcgcg ctaacaaccg gttcgatagc ggcggcgaca
    38221 gggacctcag tcaccatcgg ctgcacatgt acttcttcct gttcgcgctg ctcttcaacc
    38281 tgtacatctt gcggacgtac aattggatag cggatccaga ctttgccaga ggccagttcc
    38341 ggagacgcgc acgctacggt caacggcatt ggcgactggg ttggataacg ctcgtcacga
    38401 tagcgacgac gacgctgacc acttacgcgc aggtgacgag gcgagcggcg agaacgacgc
    38461 ggcatgccac cgttgtcacg gttatcagca ttgttctctt cttgctgttc tggtgcagtt
    38521 tgcgctacga ctggcagcgg gactttcacc agttctgtgc gtggagctgg cgcttcctga
    38581 acaattggtt cggcagcgac agtttcttca accaccggtg cgactaccgc ttcttcggct
    38641 acgctttgct cgtaacgcac tttctgattg agctgacgct gtttacgacg cggctgaacc
    38701 ggacgtacac gttcttcctg ttcggtttcc tgaacagatt gctcttcaac attcagcgcc
    38761 ttcgcttctt gttgcgcctg acgtttatca tcattacggc ggcggctacg ttcacgacgc
    38821 ggcgcttgct gctcgtcggc ggtacgcgct ttttccgtta cctcagcctg ctgacggctc
    38881 tcacgcgtct cggcagtctg ctgctgtgcc tggcgacgat tacgacggtt ttcttcgcga
    38941 ttatcgctgc cttcagtacg ttcactacgg gtgtcgcggc gctcattacg gtcacggcgg
    39001 ttgttctgac gaggcttgcg acgatcctgt tgacgttccg gtttcgcttc tgctttcggt
    39061 gctggttgct cggtcggttt ggtttcttca ccaccgctga acagcgcttt cagtgcgccg
    39121 aagaagcggc tcaacagccc aggttgtgca ggagctactg gtgttgccgg tgcagctttc
    39181 ggtgctggag ctacaacagg cgcggcaggt tcagctggcg ttggcgcagg cggcacatcc
    39241 ggcatggcaa aggttgccag cgcaggttgt tccggacgct tacgttcagc gaactcttct
    39301 tcagacggca gcgccatcgc ttcttcatgc agcttcggca gcatgtagct taaggttggg
    39361 gtttcttccc ctttacgcac gcgcagcacg tggtagtgcg gggtttccat ctgatcgttt
    39421 ggcacaatta cacagcgcac accgtcctga cgagtttcaa tggcatttac cgcagaacgt
    39481 ttttcattca gcaggtaaga agcgattggc acaggaacaa tggcgtgaac ttcctgggtg
    39541 ttctctttca gcgcttcttc ttcgatcaga cgcagaatag agagcgacag cgattcgttg
    39601 tcacgcacgg tgccagtacc agaacaacgc ggacaaacgt gatgactgga ttcacccagt
    39661 gatgggctca ggcgctgacg ggacatttcc agcaggccaa agcgagaaat atggctgatt
    39721 tgaatacgcg cacggtcctg acgcaccgct tcacgcagac ggttttctac cgcacgctgg
    39781 tggcgtactg gcgtcatgtc gatgaagtcg ataacaatca ggccgccgag gtcacgcagg
    39841 cgcagctgac gagcaatctc atcggcagct tcgaggttag tgttaaacgc ggtttcttcg
    39901 atatcgccgc cgcgggtcgc gcgtgcggag ttgatgtcga tggccgttaa cgcttcggtg
    39961 ctgtcgataa caatggaacc accagacggc agacgaactt cacgctggaa ggcggactcg
    40021 atctgtgact cgatctggta gtggctgaac agcgggatct cgccggtgta cagtttgatt
    40081 ttgctgctga aatccgggcg acctaatgca gcgatatgct gacgtgccag ttcgagcact
    40141 ttcgggttat cgataaggat ttcgccgatg tcctgacgta agtaatcgcg gaatgcgcga
    40201 acgattacgt tgctctcctg atgaatcagg aacggggccg ggcggctttc agcggctttt
    40261 ttgatggctt cccagtgttt cagacggaag cttaaatccc attgcagcgc ctcagcagat
    40321 ttgccgacgc cagcggtgcg cacgataagc cccatgcctt ccggcagttc aaggcttgcc
    40381 agtgcttctt ttaattcggt acggtcgtcg ccttcgatac ggcgagaaat gccacccgcg
    40441 cgcgggttgt tcggcatcag aaccagatag ctacccgcca gactgataaa ggtggttaat
    40501 gccgcgcctt tgttgccgcg ctcttcttta tcgatctgaa caatgacttc ctgaccttca
    40561 cgcaacacat ctttaatgtt gggacgacca tgagcactgt agttagcagg gaaatattcg
    40621 cgggcaattt cttttagtgg gaggaaaccg tgacgttcag cgccgtaatc aacaaaagca
    40681 gcttccagac tcggttcaat gcgggtgatt ttacctttgt agatgtttgc ctttttctgc
    40741 tcgtgccctg gactttcgat atccaggtca tacagacgct gcccatctac aagggcaacg
    40801 cgcaactctt cctgctgagt tgcgttgatt aacattcttt tcatcgtaac ttactcatta
    40861 ttcttacatt gacgactaag ctgcgggcaa agtaacgcct ttccgggtgt gaaccgatgg
    40921 cctcgtgtct agtcgcgtcg ccaacctcac ggttatcgtc agctcaaaga ggcgcagagt
    40981 gtcggttgcc cgtttttcat gcggaaaaac agcgcaatta tcaaagaaac agactgggta
    41041 ttactctcca gaaatatttc catctaccgg taaggactgc aacccgcagc ccgctaactg
    41101 cctgaaagat caatacgtct tacgccattg ctgcgtggat gatcggtcgg gcaaaatggg
    41161 ttattccgta aaatttcttg ttttaacaag gatggacacg gaaacggcct cattattcca
    41221 ctgcaagcct tgttatagca agatgacttt taccatttat cacccgctta ctcacagttt
    41281 tttcacttct tgctggtgat tggtttaata accatcaata aagtgatcac gcagtgaagt
    41341 aataaggtgc aaaagtaaat ataagcatag aaaaatgagt ggcgcgaatc ctgttggcta
    41401 attagaatcg ccaaccatga aaacagagac tccatccgta aaaattgttg ctatcaccgc
    41461 tgacgaagcg gggcaacgta tcgataactt tttgcgtacc caattgaaag gcgtaccaaa
    41521 aagtatgatt taccgtattt tgcgtaaagg cgaagtgcgg gtgaacaaaa aacgtattaa
    41581 gcctgaatat aaactcgaag cgggtgatga ggtgcgtatt ccaccggttc gcgttgctga
    41641 gcgggaagaa gaggcggttt cgccacatct gcaaaaggtg gcggcgctgg cggacgtcat
    41701 cttatatgaa gatgatcaca tcctggtgct gaataaacct tccggtacgg cggtacatgg
    41761 cggcagtggt ttaagcttcg gcgttattga aggtttgcgg gcgttgcgcc cggaagcgcg
    41821 gttccttgaa ctggttcatc gtcttgaccg ggacacctca ggtgttttgc tggtagcgaa
    41881 aaaacgctcg gcgttgcgtt ctctgcatga gcaattacgt gaaaaaggga tgcaaaaaga
    41941 ttacctggcg ctggtgcgcg gtcagtggca gtcgcatgtg aagagcgttc aagcaccgtt
    42001 actgaaaaat attctgcaaa gcggcgaacg tatcgtgcgt gtgagtcagg aaggcaaacc
    42061 gtcggaaaca cgctttaaag tggaagaacg ctatgcattt gccaccctgg tgcgttgtag
    42121 cccggtaaca gggcgtactc accagatccg tgtgcataca caatatgcgg gtcatccgat
    42181 tgcctttgac gatcgctacg gtgaccgtga atttgacagg cagctcactg aagcaggcac
    42241 gggattaaat cgcctgttcc tgcacgctgc agcgttgaag tttactcatc cggggaccgg
    42301 tgaggtgatg cgtatcgaag ctccgatgga tgaaggtttg aagcgttgtt tgcaaaagct
    42361 gcgtaacgcg cgctaataca agcatataaa cctgataatg ggcggttggc ctgataaggc
    42421 gtttacgccg catcaggccg ccagcaccga ttgccggatg cgacgtaacc acatccggcg
    42481 caaaaaacta tcccatcagc gggtttttcc cttcccgacg taacatctga cacagcgcga
    42541 ttagcggtaa accaaccagc gtgttaggat cacgcccctc taaacgctca aacagcgtaa
    42601 tgccaaatcc ttcactctta aagctacccg cgcagtgcag gggatgctct ttacgcacgt
    42661 aattatcaat ctccgcctcg ctcaggtgac ggaaatggac gtcaaaaggc tccacttctg
    42721 tttgcagatg cccattcgcc gaattaaaca acgccagtcc agtatagaag gtgacgatat
    42781 tgccgctggc tttgcgtaat tgcagacggg cattttcttc cgttaacggt ttaccggtga
    42841 tttcgccatc aagaacacat acctggtctg aaccaataat taaatgatcc ggataacgtg
    42901 acgccagaga ttgcgctttt tcttgtgcca gtcgaagcac caactgtcgc ggtgattcgt
    42961 cgctgcgtgg ggtttcgtcg acctctggtg ctgcacattc aaaagagatt tgcagttttt
    43021 ccagaagagc gcgacgccat ggcgaggtgg aggctaaaat aagtttaggc atattttttt
    43081 ccatcagata tagcgtattg atgatagcca ttttaaacta tgcgcttcgt tttgcaggtt
    43141 gatgtttgtt atcagcactg aacgaaaata aagcagtaac ccgcaatgtg tgcgaattat
    43201 tggcaaaagg caaccacagg ctgccttttt ctttgactct atgacgttac aaagttaata
    43261 tgcgcgccct atgcaaaagg taaaattacc cctgactctc gatccggttc gtacggctca
    43321 aaaacgcctt gattaccagg gtatctatac ccctgatcag gttgagcgcg tcgccgaatc
    43381 cgtagtcagt gtggacagtg atgtggaatg ctccatgtcg ttcgctatcg ataaccaacg
    43441 tctcgcagtg ttaaacggcg atgcgaaggt gacggtaacg ctcgagtgtc agcgttgcgg
    43501 gaagccgttt actcatcagg tctacacaac gtattgtttt agtcctgtgc gttcagacga
    43561 acaggctgaa gcactgccgg aagcgtatga accgattgag gttaacgaat tcggtgaaat
    43621 cgatctgctt gcaatggttg aagatgaaat catcctcgcc ttgccggtag ttccggtgca
    43681 tgattctgaa cactgtgaag tgtccgaagc ggacatggtc tttggtgaac tgcctgaaga
    43741 agcgcaaaag ccaaacccat ttgccgtatt agccagctta aagcgtaagt aattggtgct
    43801 ccccgttgga tcggggataa accgtaattg aggagtaagg tccatggccg tacaacagaa
    43861 taaaccaacc cgttccaaac gtggcatgcg tcgttcccat gacgcgctga ccgcagtcac
    43921 cagcctgtct gtagacaaaa cttctggtga aaaacacctg cgtcaccaca tcactgccga
    43981 cggttactac cgcggccgca aggtcatcgc taagtaatca cgcatctgcg tgatgaagct
    44041 tagtgaggat tttccccagg caactgggga aagaccaaac cgggcggcga cgataccttg
    44101 acacgtctaa ccctggcgtt agatgtcatg ggaggggatt ttggcccttc cgtgacagtg
    44161 cctgcagcat tgcaggcact gaattctaat tcgcaactca ctcttctttt agtcggcaat
    44221 cccgacgcca tcacgccatt acttgctaaa gctgactttg aacaacgttc gcgtctgcag
    44281 attattcctg cgcagtcagt tatcgccagt gatgcccggc cttcgcaagc tatccgcgcc
    44341 agtcgtggga gttcaatgcg cgtggccctg gagctggtga aagaaggtcg agcgcaagcc
    44401 tgtgtcagtg ccggtaatac cggggcgctg atggggctgg caaaattatt actcaagccc
    44461 ctggagggga ttgagcgtcc ggcgctggtg acggtattac cacatcagca aaagggcaaa
    44521 acggtggtcc ttgacttagg ggccaacgtc gattgtgaca gcacaatgct ggtgcaattt
    44581 gccattatgg gctcagttct ggctgaagag gtggtggaaa ttcccaatcc tcgcgtggcg
    44641 ttgctcaata ttggtgaaga agaagtaaag ggtctcgaca gtattcggga tgcctcagcg
    44701 gtgcttaaaa caatcccttc tatcaattat atcggctatc ttgaagccaa tgagttgtta
    44761 actggcaaga cagatgtgct ggtttgtgac ggctttacag gaaatgtcac attaaagacg
    44821 atggaaggtg ttgtcaggat gttcctttct ctgctgaaat ctcagggtga agggaaaaaa
    44881 cggtcgtggt ggctactgtt attaaagcgt tggctacaaa agagcctgac gaggcgattc
    44941 agtcacctca accccgacca gtataacggc gcctgtctgt taggattgcg cggcacggtg
    45001 ataaaaagtc atggtgcagc caatcagcga gcttttgcgg tcgcgattga acaggcagtg
    45061 caggcggtgc agcgacaagt tcctcagcga attgccgctc gcctggaatc tgtataccca
    45121 gctggttttg agctgctgga cggtggcaaa agcggaactc tgcggtagca ggacgctgcc
    45181 agcgaactcg cagtttgcaa gtgacggtat ataaccgaaa agtgactgag cgtacatgta
    45241 tacgaagatt attggtactg gcagctatct gcccgaacaa gtgcggacaa acgccgattt
    45301 ggaaaaaatg gtggacacct ctgacgagtg gattgtcact cgtaccggta tccgcgaacg
    45361 ccacattgcc gcgccaaacg aaaccgtttc aaccatgggc tttgaagcgg cgacacgcgc
    45421 aattgagatg gcgggcattg agaaagacca gattggcctg atcgttgtgg caacgacttc
    45481 tgctacgcac gctttcccga gcgcagcttg tcagattcaa agcatgttgg gcattaaagg
    45541 ttgcccggca tttgacgttg cagcagcctg cgcaggtttc acctatgcat taagcgtagc
    45601 cgatcaatac gtgaaatctg gggcggtgaa gtatgctctg gtcgtcggtt ccgatgtact
    45661 ggcgcgcacc tgcgatccaa ccgatcgtgg gactattatt atttttggcg atggcgcggg
    45721 cgctgcggtg ctggctgcct ctgaagagcc gggaatcatt tccacccatc tgcatgccga
    45781 cggtagttat ggtgaattgc tgacgctgcc aaacgccgac cgcgtgaatc cagagaattc
    45841 aattcatctg acgatggcgg gcaacgaagt cttcaaggtt gcggtaacgg aactggcgca
    45901 catcgttgat gagacgctgg cggcgaataa tcttgaccgt tctcaattgg actggctggt
    45961 tccgcatcag gctaacctgc gtattatcag tgcaacggcg aaaaaactcg gtatgtctat
    46021 ggataatgtc gtggtgacgc tggatcgcca cggtaatacc tctgcggcct ctgtcccgtg
    46081 cgcgctggat gaagctgtac gcgacgggcg cattaagccg gggcagttgg ttctgcttga
    46141 agcctttggc ggtggattca cctggggctc cgcgctggtt cgtttctagg ataaggatta
    46201 aaacatgacg caatttgcat ttgtgttccc tggacagggt tctcaaaccg ttggaatgct
    46261 ggctgatatg gcggcgagct atccaattgt cgaagaaacg tttgctgaag cttctgcggc
    46321 gctgggctac gacctgtggg cgctgaccca gcaggggcca gctgaagaac tgaataaaac
    46381 ctggcaaact cagcctgcgc tgttgactgc atctgttgcg ctgtatcgcg tatggcagca
    46441 gcagggcggt aaagcaccgg caatgatggc cggtcacagc ctgggggaat actccgcgct
    46501 ggtttgcgct ggtgtgattg atttcgctga tgcggtgcgt ctggttgaga tgcgcggcaa
    46561 gttcatgcaa gaagccgtac cggaaggcac gggcgctatg gcggcaatca tcggtctgga
    46621 tgatgcgtct attgcgaaag cgtgtgaaga agctgcagaa ggtcaggtcg tttctccggt
    46681 aaactttaac tctccgggac aggtggttat tgccggtcat aaagaagcgg ttgagcgtgc
    46741 tggcgctgcc tgtaaagcgg cgggcgcaaa acgcgcgctg ccgttaccag tgagcgtacc
    46801 gtctcactgt gcgctgatga aaccagcagc cgacaaactg gcagtagaat tagcgaaaat
    46861 cacctttaac gcaccaacag ttcctgttgt gaataacgtt gatgtgaaat gcgaaaccaa
    46921 tggtgatgcc atccgtgacg cactggtacg tcagttgtat aacccggttc agtggacgaa
    46981 gtctgttgag tacatggcag cgcaaggcgt agaacatctc tatgaagtcg gcccgggcaa
    47041 agtgcttact ggcctgacga aacgcattgt cgacaccctg accgcctcgg cgctgaacga
    47101 accttcagcg atggcagcgg cgctcgagct ttaaaagagg aaaatcatga attttgaagg
    47161 aaaaatcgca ctggtaaccg gtgcaagccg cggaattggc cgcgcaattg ctgaaacgct
    47221 cgcagcccgt ggcgcgaaag ttattggcac tgcgaccagt gaaaatggcg ctcaggcgat
    47281 cagtgattat ttaggtgcca acggcaaagg tctgatgttg aatgtgaccg acccggcatc
    47341 tatcgaatct gttctggaaa aaattcgcgc agaatttggt gaagtggata tcctggtcaa
    47401 taatgccggt atcactcgtg ataacctgtt aatgcgaatg aaagatgaag agtggaacga
    47461 tattatcgaa accaaccttt catctgtttt ccgtctgtca aaagcggtaa tgcgcgctat
    47521 gatgaaaaag cgtcatggtc gtattatcac tatcggttct gtggttggta ccatgggaaa
    47581 tggcggtcag gccaactacg ctgcggcgaa agcgggcttg atcggcttca gtaaatcact
    47641 ggcgcgcgaa gttgcgtcac gcggtattac tgtaaacgtt gttgctccgg gctttattga
    47701 aacggacatg acacgtgcgc tgagcgatga ccagcgtgcg ggtatcctgg cgcaggttcc
    47761 tgcgggtcgc ctcggcggcg cacaggaaat cgccaacgcg gttgcattcc tggcatccga
    47821 cgaagcagct tacatcacgg gtgaaacttt gcatgtgaac ggcgggatgt acatggtctg
    47881 accgcgattt gcacaaaatg ctcatgttgc gcgcagtctg cgtggttatg agtaataatt
    47941 agtgcaaaat gatttgcgtt attggggggt aaggcctcaa aataacgtaa aatcgtggta
    48001 agacctgccg ggatttagtt gcaaattttt caacatttta tacactacga aaaccatcgc
    48061 gaaagcgagt tttgatagga aatttaagag tatgagcact atcgaagaac gcgttaagaa
    48121 aattatcggc gaacagctgg gcgttaagca ggaagaagtt accaacaatg cttctttcgt
    48181 tgaagacctg ggcgcggatt ctcttgacac cgttgagctg gtaatggctc tggaagaaga
    48241 gtttgatact gagattccgg acgaagaagc tgagaaaatc accaccgttc aggctgccat
    48301 tgattacatc aacggccacc aggcgtaagt gaacatctcc aggcggtcgt tcgaccgcct
    48361 gagttttatc tttttgtccc actagaatca ttttttccct ccctggagga caaacgtgtc
    48421 taagcgtcgt gtagttgtga ccggactggg catgttgtct cctgtcggca ataccgtaga
    48481 gtctacctgg aaagctctgc ttgccggtca gagtggcatc agcctaatcg accatttcga
    48541 tactagcgcc tatgcaacga aatttgctgg cttagtaaag gattttaact gtgaggacat
    48601 tatctcgcgc aaagaacagc gcaagatgga tgccttcatt caatatggaa ttgtcgctgg
    48661 cgttcaggcc atgcaggatt ctggccttga aataacggaa gagaacgcaa cccgcattgg
    48721 tgccgcaatt ggctccggga ttggcggcct cggactgatc gaagaaaacc acacatctct
    48781 gatgaacggt ggtccacgta agatcagccc attcttcgtt ccgtcaacga ttgtgaacat
    48841 ggtggcaggt catctgacta tcatgtatgg cctgcgtggc ccgagcatct ctatcgcgac
    48901 tgcctgtact tccggcgtgc acaacattgg ccatgctgcg cgtattatcg cgtatggcga
    48961 tgctgacgtg atggttgcag gtggcgcaga gaaagccagt acgccgctgg gcgttggtgg
    49021 ttttggcgcg gcacgtgcat tatctacccg caatgataac ccgcaagcgg cgagccgccc
    49081 gtgggataaa gagcgtgatg gtttcgtact gggcgatggt gccggtatgc tggtacttga
    49141 agagtacgaa cacgcgaaaa aacgcggtgc gaaaatttac gctgaactcg tcggctttgg
    49201 tatgagcagc gatgcttatc atatgacgtc accgccagaa aatggcgcag gcgcagctct
    49261 ggcgatggca aatgctctgc gtgatgcagg cattgaagcg agtcagattg gctacgttaa
    49321 cgcgcacggt acttctacgc cggctggcga taaagctgaa gcgcaggcgg tgaaaaccat
    49381 cttcggtgaa gctgcaagcc gtgtgttggt aagctccacg aaatctatga ccggtcacct
    49441 gttaggtgcg gcgggtgcag tagaatctat ctactccatc ctggcgctgc gcgatcaggc
    49501 tgttccgcca accatcaacc tggataaccc ggatgaaggt tgcgatctgg atttcgtacc
    49561 gcacgaagcg cgtcaggtta gcggaatgga atacactctg tgtaactcct tcggcttcgg
    49621 tggcactaat ggttctttga tctttaaaaa gatctaagtt gtcattttcc acccttataa
    49681 aaggtccgct tgcgggcctt ttttcttagc ttttattccg acttgttccg tagtgaacat
    49741 gctgccacac taacaattct ctgataagga gccggtatgt tcttaattaa cggtcataag
    49801 caggaatcgc tggcagtaag cgatcgggca acgcagtttg gtgatggttg ttttaccacc
    49861 gccagagtta tcgacggtaa agtcagtttg ttatcggcgc atatccagcg actacaggat
    49921 gcttgtcagc ggttgatgat ttcctgtgac ttctggcctc agcttgaaca agagatgaaa
    49981 acgctggcag cagaacagca aaatggtgtg ctgaaagtcg tgatcagtcg cggtagtggc
    50041 gggcgagggt acagcacatt gaacagcgga ccggcaacgc ggattctctc cgttacggct
    50101 tatcctgcac attacgaccg tttgcgtaac gaggggatta cgttggcgct aagcccggtg
    50161 cggctggggc gcaatcctca tcttgcaggt attaaacatc tcaatcgtct tgagcaagta
    50221 ttgattcgct ctcatcttga gcagacaaac gctgatgagg cgctggtcct tgacagcgaa
    50281 gggtgggtta cggaatgctg tgcggctaat ttgttctggc ggaagggcaa cgtagtttat
    50341 acgccgcgac tggatcaggc aggtgttaac ggcattatgc gacaattctg tatccgtttg
    50401 ctggcacaat cctcttatca gcttgtcgaa gtgcaagcct ctctggaaga gtcgttgcag
    50461 gcagatgaga tggttatttg taatgcgtta atgccagtga tgcccgtatg tgcctgtggc
    50521 gatgtctcct tttcgtcagc aacgttatat gaatatttag ccccactttg tgagcgcccg
    50581 aattagtcat gaaaaaagtg ttattgataa tcttgttatt gctggtggta ctgggtatcg
    50641 ccgctggtgt gggcgtctgg aaggttcgcc atcttgccga cagcaaattg cttatcaaag
    50701 aagagacgat atttaccctg aagccaggga ccggacgtct ggcgctcggt gaacagcttt
    50761 atgccgataa gatcatcaat cgtccacggg tttttcaatg gctgctgcgt atcgaaccgg
    50821 atctttctca ctttaaagcc gggacttacc gctttacacc gcagatgacc gtgcgcgaga
    50881 tgctgaaatt gctggaaagc ggtaaagaag cacagttccc tctgcgactg gtagaaggga
    50941 tgcgtctgag cgattacctc aagcaattgc gtgaggcccc gtatatcaag catacgctga
    51001 gcgatgataa gtacgccacc gtagcgcagg cacttgaact ggaaaacccg gagtggattg
    51061 aaggttggtt ctggccagac acctggatgt ataccgccaa taccaccgat gtcgcgttac
    51121 tcaagcgagc gcacaagaaa atggtgaaag cggtcgatag cgcctgggaa gggcgtgcgg
    51181 acggtctgcc ttataaagat aaaaaccagt tggtgacgat ggcatcaatt atcgaaaaag
    51241 aaaccgccgt tgccagtgaa cgcgataagg ttgcctcagt atttatcaac cgtttacgca
    51301 ttggtatgcg cctgcagacc gacccgaccg tgatttacgg gatgggagag cgttataatg
    51361 gcaaactttc tcgtgcagac ctggaaacgc cgacagcgta taacacctat accattaccg
    51421 gtctgccgcc aggtgcgata gcgacgccgg gggcggattc gctgaaggct gctgcgcatc
    51481 cggcaaaaac gccgtatctc tattttgtgg ccgatggtaa aggtggtcac acgtttaata
    51541 ccaatcttgc cagtcataac aagtctgtgc aggattatct gaaagtgctt aaggaaaaaa
    51601 atgcgcagta agtatatcgt cattgagggg ctggaaggcg caggcaaaac taccgcgcgt
    51661 aatgtggtgg ttgagacgct cgagcaactg ggtatccgcg acatggtttt cactcgggaa
    51721 cctggcggta cgcaacttgc cgaaaagtta agaagcctgg tgctggatat caaatcggta
    51781 ggcgatgaag tcattaccga taaagccgaa gttctgatgt tttatgccgc gcgcgttcaa
    51841 ctggtagaaa cggtcatcaa accagctctg gctaacggca cctgggtgat tggcgatcgc
    51901 cacgatctct ccactcaggc gtatcagggc ggcggacgtg gtattgacca acatatgctg
    51961 gcaacactgc gtgatgctgt tctcggggat tttcgccccg acttaacgct ctatctcgat
    52021 gttaccccgg aagttggctt aaaacgcgcg cgtgcgcgcg gcgagctgga tcgtattgag
    52081 caagaatctt tcgatttctt taatcgcacc cgcgcccgct atctggaact ggcagcacaa
    52141 gataaaagca ttcataccat tgatgccacc cagccgctgg aggccgtgat ggatgcaatc
    52201 cgcactaccg tgacccactg ggtgaaggag ttggacgcat gagatggtat ccatggttac
    52261 gacctgattt cgaaaaactg gtagccagct atcaggccgg aagaggtcac catgcgctac
    52321 tcattcaggc gttaccgggc atgggcgatg atgctttaat ctacgccctg agccgttatt
    52381 tactctgcca acaaccgcag ggccacaaaa gttgcggtca ctgtcgtgga tgtcagttga
    52441 tgcaggctgg cacgcatccc gattactaca ccctggctcc cgaaaaagga aaaaatacgc
    52501 tgggcgttga tgcggtacgt gaggtcaccg aaaagctgaa tgagcacgca cgcttaggtg
    52561 gtgcgaaagt cgtttgggta accgatgctg ccttactaac cgacgccgcg gctaacgcat
    52621 tgctgaaaac gcttgaagag ccaccagcag aaacctggtt tttcctggct acccgcgagc
    52681 ctgaacgttt actggcaaca ttacgtagtc gttgtcggtt acattacctt gcgccgccgc
    52741 cggaacagta cgccgtgacc tggctttcac gcgaagtgac aatgtcacag gatgcattac
    52801 ttgccgcatt gcgcttaagc gccggttcgc ctggcgcggc actggcgttg tttcagggag
    52861 ataactggca ggctcgtgaa acattgtgtc aggcgttggc atatagcgtg ccatcgggcg
    52921 actggtattc gctgctagcg gcccttaatc atgaacaagc tccggcgcgt ttacactggc
    52981 tggcaacgtt gctgatggat gcgctaaaac gccatcatgg tgctgcgcag gtgaccaatg
    53041 ttgatgtgcc gggcctggtc gccgaactgg caaaccatct ttctccctcg cgcctgcagg
    53101 ctatactggg ggatgtttgc cacattcgtg aacagttaat gtctgttaca ggcatcaacc
    53161 gcgagcttct catcaccgat cttttactgc gtattgagca ttacctgcaa ccgggcgttg
    53221 tgctaccggt tcctcatctt taagagagac atcatgtttt tagtcgactc acactgccat
    53281 ctcgatggtc tggattatga atctttgcat aaggacgtgg atgacgttct ggcgaaagcc
    53341 gccgcacgcg atgtgaaatt ttgtctggca gtcgccacaa cattaccggg ttatttacat
    53401 atgcgggatc tggtaggcga acgtgacaac gtcgtatttt cttgtggcgt gcatccactc
    53461 aaccagaatg atccctacga tgtagaagat ttacgccgtc tggcggcaga agagggtgtt
    53521 gtagcgctgg gtgaaaccgg gctggattat tattacacgc cggaaactaa agtacgtcag
    53581 caagagtcct tcatccatca tatccagatt ggtcgtgaac tgaacaagcc ggttatcgtc
    53641 catacccgtg acgcccgtgc cgatacgctg gcaattctgc gcgaagaaaa agtgacggat
    53701 tgcggtggcg tactacactg ttttacagag gacagagaaa cggcgggtaa attactggat
    53761 ctcggatttt acatctcctt ttccggcatt gtgaccttcc gtaatgcgga gcaactgcgc
    53821 gatgctgcgc gttatgtccc cctggatcgg ttactggtgg aaactgactc accttacctt
    53881 gcgccggtac cgcatcgagg aaaagagaat caacctgcga tggttcgtga cgttgcagaa
    53941 tacatggctg tgttgaaagg tgttgccgtt gaagaactgg cgcaggtaac caccgataac
    54001 ttcgcccgtc tgtttcacat cgacgcttcc cgccttcaat ccatccgttg aatgagtttt
    54061 tttaaagctc gtaattaatg gctaaaacga gtaaagttca ccgccgaaaa ttgggcggtg
    54121 aataaccacg tttgaaatat tgtgacatat gttttgtcaa aatgtgcaac ttctccaatg
    54181 atctgaagtt gaaacgtgat agccgtcaaa caaattggca ctgaattatt ttactctgtg
    54241 taataaataa agggcgctta gatgccctgt acacggcgag gctctccccc cttgccacgc
    54301 gtgagaacgt aaaaaaagca cccatactca ggagcactct caattatgtt taagaatgca
    54361 tttgctaacc tgcaaaaggt cggtaaatcg ctgatgctgc cggtatccgt actgcctatc
    54421 gcaggtattc tgctgggcgt cggttccgcg aatttcagct ggctgcccgc cgttgtatcg
    54481 catgttatgg cagaagcagg cggttccgtc tttgcaaaca tgccactgat ttttgcgatc
    54541 ggtgtcgccc tcggctttac caataacgat ggcgtatccg cgctggccgc agttgttgcc
    54601 tatggcatca tggttaaaac catggccgtg gttgcgccac tggtactgca tttacctgct
    54661 gaagaaatcg cctctaaaca cctggcggat actggcgtac tcggagggat tatctccggt
    54721 gcgatcgcag cgtacatgtt taaccgtttc taccgtatta agctgcctga gtatcttggc
    54781 ttctttgccg gtaaacgctt tgtgccgatc atttctggcc tggctgccat ctttactggc
    54841 gttgtgctgt ccttcatttg gccgccgatt ggttctgcaa tccagacctt ctctcagtgg
    54901 gctgcttacc agaacccggt agttgcgttt ggcatttacg gtttcatcga acgttgcctg
    54961 gtaccgtttg gtctgcacca catctggaac gtacctttcc agatgcagat tggtgaatac
    55021 accaacgcag caggtcaggt tttccacggc gacattccgc gttatatggc gggtgacccg
    55081 actgcgggta aactgtctgg tggcttcctg ttcaaaatgt acggtctgcc agctgccgca
    55141 attgctatct ggcactctgc taaaccagaa aaccgcgcga aagtgggcgg tattatgatc
    55201 tccgcggcgc tgacctcgtt cctgaccggt atcaccgagc cgatcgagtt ctccttcatg
    55261 ttcgttgcgc cgatcctgta catcatccac gcgattctgg caggcctggc attcccaatc
    55321 tgtattcttc tggggatgcg tgacggtacg tcgttctcgc acggtctgat cgacttcatc
    55381 gttctgtctg gtaacagcag caaactgtgg ctgttcccga ttgtcggtat cggttatgcg
    55441 attgtttact acaccatctt ccgcgtgctg attaaagcac tggatctgaa aacgccgggt
    55501 cgtgaagacg cgactgaaga tgcaaaagcg acaggtacca gcgaaatggc accggctctg
    55561 gttgctgcat ttggtggtaa agaaaacatt actaacctcg acgcatgtat tacccgtctg
    55621 cgcgtcagcg ttgctgatgt gtctaaagtg gatcaggccg gcctgaagaa actgggcgca
    55681 gcgggcgtag tggttgctgg ttctggtgtt caggcgattt tcggtactaa atccgataac
    55741 ctgaaaaccg agatggatga gtacatccgt aaccactaat ccgtaagacg ttggggagac
    55801 taaggcagcc agatggctgc cttttttaca ggtgttattc agaattgata cgtgccggta
    55861 atgctgaaat tacgcggtgt gccgtagacg atagaacctt ccacgttggt atcgtaggtt
    55921 ttgtcgaaca ggttattgac gttcccctgt aacgagaagt ttttcgtcac ctggtagcgg
    55981 gtgaagagat ccaccagcgc gtagctacct tgctcggcgc ggaaggtgcc atacggcgtc
    56041 acggtgtcgg tatacacgcg attttgccag ttaacaccac cgccgaccgt caactctggc
    56101 atgacaggca accgatagct ggtgaacatt ttaaccgtgg tgcgtggcag attaggatta
    56161 acggcgtttc cttcgttatc ctctgcaata tagcgcgttg cgccaaatgt cagctgccag
    56221 ttgtcggtaa ttgcgccgtt gagttcaaat tccacccctt tactgactgt cccatccacc
    56281 gctttatagg cggtttcgcc gttgctgccg gggataggtg taccggtgga ctgagcgaca
    56341 ttatcctgct caatacggaa gatggctaac gtggtggtca gacggctatt catccagtcc
    56401 gatttcagac ccagctcgta gttgttaccg gtgattggag ccagatattt gcctgaactg
    56461 tcacgatcat tttgcggctg gaaaatagag gtatagctgg cgtaggtcga ccagttgtca
    56521 ttgatgtcaa acaccagacc agcgtaaggc gtggtgtggt ttttctccat gctgtaagtc
    56581 agcgtatcaa cccgccagtt ggtataacgt gcgccgagga tcagatgcag cggatcggca
    56641 agggtgacac gagtggcagc atataacgat ttcatatgtg tggtatcgtc ctgcgccagg
    56701 ctctgtggtg accagtcggt ttgtgggaaa ttgccattaa agttgtagaa actgccaatt
    56761 tcatccggga agatgttggc ccatgaactg aagtaacgat tgttttgttt gctgtaactg
    56821 ccaccaaaca ttagattgtg ctgacgacca aacaattcat aactaccgtc agcgaacaaa
    56881 tccagcgcat caactttacg tttgccactg ttccaaccgg tgccgccgac ataatcaaag
    56941 ccaggtccat aattactgta tggcccaacc agcataccat ccgctttgtt tacataggca
    57001 tcgacataca tcattttgct gtcaaattcg acttcagagt gggtggcatt cagtgtcgct
    57061 tgccaggtat cagcaaactg ctgcttcagg gtcataaaga ccttgttgat ctctttatcg
    57121 ttgtacgccc agtcaggtgc ggtactgcgt gcgcgatcgt aactgttgct gctgccatca
    57181 gtattccagc gcggtaaacc gccccaggta gggctattaa catcaatgcg ctgatattcg
    57241 taaccggctg aaagcgtcgt aagatcgcct aaatcagcat cgacaatgcc cgagaagaag
    57301 gtcttttcac tgttgtagcg gtccagccat gagtcgttat tctggtagcc gccgacaatt
    57361 cgcgcgcgga ttttaccgtc ttcggtgagt gggctttgta aatccgccac ataccgttct
    57421 ttgttccagc taccgtattc cgccgagaca tcgcctttaa attcacgact ggtcgcgtgt
    57481 tttcgaacca tattaattgc cgcagatgga ttacccgtcc cggtcatgag tcctgtcgcg
    57541 ccacgcacta cttctacgcg ttcaaagagt gccatatcag aaagtgcatc gcccagattc
    57601 cagcgcgatt caaaataggt ggggatacca tcaaccatat agttatcgat ctggaatccg
    57661 cgggaataat aaagagcacg atcggaatcc gcctgacttt tgctgatccc cagcgtgttt
    57721 tccatcactt cgcccagcgt ttgtaactgc tgatcttcca tccgctgctg gctaacaata
    57781 gtgaccgact gaggaatatc acgttgagtc atctgcattt tggtacccgc agaggtagac
    57841 gttacgctgt aatcattttc gccatcatct ggagctgtgg ctgaaccctc aacaatcacc
    57901 gtttcttcag tggctggtgc agcaaaagcg gcagaaggta atagtgccag tgctatgcaa
    57961 ccggcaagta gtgacggttt ggtgatggct tgatattgat tatccctgtt aaattgtgtt
    58021 gaaagcattt gaaatctctt ggtttatgtt gtcgtcaggc tcatgccgga ggagggtgat
    58081 gagcgattat atttagtgtg cgaataattt tgtttgtaaa tgcaaatgag aaatatacgc
    58141 attcatattt gtcatgtaaa ccaaacagag aatgtctttt cagcgcattc gcaggcagaa
    58201 atgggaataa tggcgatata tacggcagca aaacgatttt ttgcttaaga aatcgtgagt
    58261 taaggttgaa agagcaggtt taactcgacc atactctata ctcgcagtgt ggcgcggcgt
    58321 agcatggcgc aacgcatggc tatttgaaaa aggaaaatgt cgtggcagaa gaaactatat
    58381 tcagcaaaat tattcgtcgt gagatcccct ccgatatcgt ctaccaggat gatctggtaa
    58441 cggcgtttcg cgatatttcg ccgcaagcgc caacgcatat tctgatcatt ccgaatatcc
    58501 tcattccgac tgtgaacgac gtctcagctg agcatgagca ggcgctggga cgcatgatca
    58561 ccgtagcggc aaaaattgct gagcaagaag gtattgccga agatggctat cgtctgatca
    58621 tgaataccaa ccgccatggc ggacaagagg tttaccacat ccatatgcac ttgttgggtg
    58681 gccgtccgct gggaccaatg ctggcgcata aaggtctgta acgatgagaa aaggatgctt
    58741 tgggctggtg tctctggtgt tgttactgct ggtgggctgt cgttcacatc cggaaattcc
    58801 ggtgaatgat gagcaatcgc tggtgatgga gtcatcttta ttggctgcgg gcatcagtgc
    58861 agaaaagccc ttcctttcga cgtctgatat tcaaccttca gcatcctcaa cgctttataa
    58921 cgaaaggcaa gaacccgtta ccgttcatta tcgtttttac tggtatgacg ccagagggct
    58981 ggagatgcat cctctggaaa ggccacgcag cgttaccatt cccgcacatt cggcggtaac
    59041 gctgtacggc agcgccaatt ttctgggggc gcacaaagtc agactttatc tatatttgta
    59101 aggggtgaaa cttgatgaca aaaatgagtc gctacgcctt gattaccgcg ctggcgatgt
    59161 ttctcgccgg gtgtgtgggg caacgtgaac ctgcaccggt agaagaagtg aaaccagcgc
    59221 cggaacaacc agccgagcca caacagcctg tccccacagt gccctcggtg ccgacgatcc
    59281 cgcagcagcc aggcccaatt gagcacgaag atcaaactgc accgcctgcg ccgcatattc
    59341 gctattatga ctggaatggc gcaatgcagc cgatggtcag taagatgctt ggggctgacg
    59401 gggtgactgc gggtagcgtc ctgctggttg atagcgttaa caaccgtact aacggttcgc
    59461 tgaatgccgc agaagcgacc gaaacgctgc gaaatgcgct ggctaataac gggaaattta
    59521 ccctggtttc cgcccagcaa ctgtcgatgg cgaagcaaca gttaggtttg tcgccgcagg
    59581 acagtttagg cacccgtagt aaagccatag gcattgcccg caatgtcggc gctcattacg
    59641 tgctgtactc cagcgcctct ggcaacgtta acgctccgac cctacaaatg cagctgatgc
    59701 tggtgcagac gggcgaaatt atctggtcag gtaaaggtgc cgtttcgcag caataatccc
    59761 atcacgcgcg acgaattgct gtcgcgcttt ttcccgcagt atcatcccgt cacgacgttt
    59821 aatagtgggc ttagtggcgg gagttttctc attgaacatc agggccagcg ttttgttgtg
    59881 cgtcagccgc acgatcctga tgcgccgcag tccgcgttct tgcgccagta tcgggcttta
    59941 tcacaactac ccgcatgcat tgcaccgaag ccgcatttat atctccgtga ctggatggta
    60001 gtcgactatc tgcccggcgc ggtaaaaacg tatttgccgg ataccaacga actggcaggc
    60061 ttgctgtatt atctacatca acaaccacgt tttggctggc gaataacgct gttgccgtta
    60121 ctggaactgt actggcagca aagcgatccg gcgcggcgga cagtgggttg gctgcgaatg
    60181 ttaaaacgtc tgcgcaaagc gcgggaacca cggcctttac gcttaagtcc attgcatatg
    60241 gatgtccacg ccggaaattt agtgcatagc gcgtcagggt taaaactcat cgactgggag
    60301 tatgccggag atggtgatat cgcgctggaa ctggcggcgg tgtgggtgga aaatactgaa
    60361 cagcaccggc aattggtcaa tgactatgcc actcgcgcga agatttatcc ggcgcaatta
    60421 tggcgtcagg tcaggcgatg gtttccctgg ctgctgatgc tcaaagcagg gtggtttgag
    60481 taccgctggc gacaaaccgg cgatcaacaa tttatcaggc tggccgatga cacctggcgg
    60541 cagctattaa taaaacaata aggagagcag tgtgggtcca gtaatgttgg atgtcgaagg
    60601 ttacgaactg gacgcggaag agcgtgaaat actggcgcat ccgctggtgg gagggctgat
    60661 tctctttacg cgtaactatc atgatcctgc ccagttacgt gaactggtgc gccagatccg
    60721 cgcagcttcg cgcaatcgtc tggtggtggc ggttgatcag gaaggtggac gcgtgcagcg
    60781 ttttcgtgaa ggttttaccc gcttgccagc ggcgcaatca ttcgctgcgc tgtcaggaat
    60841 ggaagagggt ggcaaactgg cgcaggaggc aggttggttg atggccagcg aaatgatcgc
    60901 tatggatatt gatatcagct ttgcgcctgt gctggatgtc gggcatatca gcgcggcgat
    60961 tggcgagcgt tcttatcatg ccgatccaca aaaagccctg gcaattgcca gccggtttat
    61021 tgatggtatg catgaagccg gaatgaaaac gaccgggaaa cacttcccag gacacggtgc
    61081 agtaacggca gactcacaca aagaaacacc gtgcgatcca cgtccacaag cggagattcg
    61141 cgctaaagat atgtcggtct tcagttcctt aatccgcgaa aataaactcg acgccattat
    61201 gcctgcgcat gtgatctaca gtgatgttga tccgcgtccg gcgagcggtt ctccctactg
    61261 gctgaaaacc gttttgcgtc aggaactggg ttttgacggc gtgattttct ctgacgattt
    61321 atcgatggaa ggtgccgcga ttatgggcag ttatgccgaa cgcgggcagg cttcactgga
    61381 tgcgggttgc gatatgatcc tggtctgcaa taatcgtaaa ggggccgtca gcgtgttaga
    61441 taatctgtca ccgatcaagg cagaacgtgt tacacgtttg tatcataaag gttcattttc
    61501 gcgacaggaa ctgatggact cggctcgctg gaaagcgatc agcacccgtc tgaatcagtt
    61561 acatgaacgc tggcaggaag agaaagcagg tcactaaccc tggcttatgt gaggaagcga
    61621 tgattatcta tttacacggt tttgactcta acagtccggg taaccacgag aaagtcttac
    61681 aattgcagtt tattgacccg gatgtacgct tgataagcta cagtacgcgg catccgaaac
    61741 atgatatgca gcatctgctt aaagaagtgg acaaaatgtt gcaactgaac gttgacgagc
    61801 gtccgctaat ttgcggcgtt ggcttgggcg gatactgggc ggaacggatt ggttttcttt
    61861 gcgacatccg ccaggtgatc ttcaacccta atttgttccc ttatgagaac atggaaggca
    61921 agattgatcg cccggaagag tatgccgata ttgccactaa gtgtgtgacc aacttccgtg
    61981 agaagaatcg cgatcgttgc ctggtgattt tgtcgcgtaa tgatgaagcg cttaacagcc
    62041 agcggacatc tgaagagttg catcattatt acgagattgt ctgggacgaa gagcagacgc
    62101 acaaattcaa gaatatctcc ccgcatttac agcgcattaa agcgttcaaa accctcgggt
    62161 aaatgccctc gtcgcatcag gtaaccttgc cggtacctga tgcgctccga attctgtggg
    62221 tcggataagg cgtccacgcc gcatccgaca gtcgagcatc aatgcctgat gcgcttctta
    62281 tcaggcctac cgaacgccct gcatacaccc ctcactctat atcactctca caaattcgct
    62341 caaataataa acaataaact ctgttttttg atctcacccg gtaaagtcgc ctatcttttc
    62401 agcaacaaaa cttgattaac atcaattttg gtatgaccaa tgcaccattc atgttattct
    62461 caatagcgaa gaacattttc attgctgtaa cctgttgtta attaagagct atgttaataa
    62521 ccattaatta acaattggtt aataaattta agggggtcac gttgactacg ccattgaaaa
    62581 agattgtgat tgtcggcggc ggtgctggtg ggctggaaat ggcaacacag ctggggcata
    62641 agctgggacg caagaaaaaa gccaaaatta cgctggtcga tcgtaaccac agccacctgt
    62701 ggaaaccgct gctgcacgaa gtggcgactg gctcgcttga tgaaggcgtc gatgcgttga
    62761 gctatctggc ccatgcgcgc aatcatggtt tccagttcca gctgggttcc gtcattgata
    62821 ttgatcgtga agcgaaaaca atcactattg cagaactgcg cgacgagaaa ggtgaactgc
    62881 tggttccgga acgtaaaatc gcctatgaca ccctggtaat ggcgctgggt agcacctcta
    62941 acgatttcaa tacgccaggt gtcaaagaga actgcatttt cctcgataac ccgcaccagg
    63001 cgcgtcgctt ccaccaggag atgctgaatt tgttcctgaa atactccgcc aacctgggcg
    63061 cgaatggcaa agtgaacatt gcgattgtcg gcggcggcgc gacgggtgta gaactctccg
    63121 ctgaattgca caacgcggtc aagcaactgc acagctacgg ttacaaaggc ctgaccaacg
    63181 aagccctgaa cgtaacgctg gtagaagcgg gagaacgtat tttgcctgcg ttaccgccac
    63241 gtatctctgc tgcggcccac aacgagctaa cgaaacttgg cgttcgcgtg ctgacgcaaa
    63301 ccatggtcac cagtgctgat gaaggcggcc tgcacactaa agatggcgaa tatattgagg
    63361 ctgatctgat ggtatgggca gccgggatca aagcgccaga cttcctgaaa gatatcggtg
    63421 gtcttgaaac taaccgtatc aaccagctgg tggtggaacc gacgctgcaa accacccgcg
    63481 atccagacat ttacgctatt ggcgactgcg cgtcatgccc gcgtccggaa gggggctttg
    63541 ttccgccgcg tgctcaggct gcacaccaga tggcgacttg cgcaatgaac aacattctgg
    63601 cgcagatgaa cggtaagccg ctgaaaaatt atcagtataa agatcatggt tcgctggtat
    63661 cgctgtcgaa cttctccacc gtcggtagcc tgatgggtaa cctgacgcgc ggctcaatga
    63721 tgattgaagg acgaattgcg cgctttgtat atatctcgct ataccgaatg catcagattg
    63781 cgctgcatgg ttactttaaa accggattaa tgatgctggt ggggagtatt aaccgcgtta
    63841 tccgtccgcg tttgaagttg cattaatcga cgtacactgg cggatgtggc ataaacgcct
    63901 catccgccct tgaggaacag cgcgatcggc agccgcgttg tatcaggcat cctttcagac
    63961 tcctccgaat ccttaagtat ttccagccat tcccgcgctt ttcatcttct gtctgatagc
    64021 tgcttttctc cttcgcttgc atgattggca taactgcaaa gaaggaggtg ttcccgtgaa
    64081 taaatcaatg ttggcgggta tcgggattgg tgtcgcagct gcgctgggcg tagcggcagt
    64141 ggccagtctg aacgtgtttg aacggggccc gcaatacgct caggttgttt ctgcaacccc
    64201 aatcaaggaa acggttaaaa caccgcgtca ggagtgtcgc aacgtcacag tgacccatcg
    64261 tcgaccggtg caggatgaaa atcgcattac cgggtcggtg ctcggcgctg ttgctggcgg
    64321 cgtgataggg catcagtttg gtggtggtcg cggtaaagat gtcgccactg ttgtgggggc
    64381 gctgggtggt ggatatgccg gtaaccagat ccagggctct ctccaggaaa gcgatactta
    64441 cacgactacg caacagcgtt gtaaaacggt gtatgacaag tcagaaaaaa tgctcggtta
    64501 tgatgtgacc tataagattg gcgatcagca gggcaaaatc cgcatggacc gcgatccggg
    64561 tacgcagatc ccgctagata gcaacgggca actgattttg aataacaaag tataacaagg
    64621 ctgtactctg caatttggcc cctcattcgc tcaggctgag gggctttttt tgcgacttat
    64681 ttcaccagtt cgggccataa acgcaaagtc gttccggcaa tctgcatcag tttttccagc
    64741 gatgcacctt cgcgtgcgct gatcgacatc ccctgaataa tacaattaag gaattctgcc
    64801 agatgtgtca cgtcacagtg gggcgggatt tccccgcgcg cttgtcgttg acataaaaac
    64861 tgctgcaaag tgcgctcttg catcgcatgg cgtgatttca acgtattggc gatatctcct
    64921 gaatctgggg agagggtggt gcagttgttg atcatgaagc agcctgccgg ggtgtctttg
    64981 ctggtaaagc agttggcgat ggcagcaaaa tagtcagcca gcgcagactc cacgcttttc
    65041 tcttcacaaa acagctgtgc ttcatgctta gcggcaaaac gatcgatata gcggtcgaga
    65101 acggcacgaa ataacccctc tttgttggta aattccgcgt atagcgtggg cgctttggct
    65161 ccggtcgctt cgacgaggtc cgcaagagaa gtcgcttcat aaccgtgttg ccagaacaat
    65221 ttcatggcct tatcaagcgc ggcatccctg tcgaacactt ttgggcggcc acggcttttt
    65281 tttacacatt gtgttgagtc agttgccatg atgccgttgt acctggtgac tgtgaatgaa
    65341 aggttattat aaaaataatc acctccgttc accagtccag atcccataaa aat
//
LOCUS       DAPOAV010000016        60828 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.016, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000016 DAPOAV010000000
VERSION     DAPOAV010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 60828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60828
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.016"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..683
                     /locus_tag="RN951_001228"
     CDS             <1..683
                     /locus_tag="RN951_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2526259.1"
                     /translation="FSFKVMYLTAAIAFVVCGLIVWLFLPSIQRNIPVVTQPVEILPS
                     THRKRDTRLLFVVCSMMWAANNLYMINMPLFIIDELHLTDKLAGEMIGIAAGLEIPMM
                     LIAGYYMKRIGKRLLMLIAIVSGMCFYASVLMATTPAVELELQILNAIFLGILCGIGM
                     LYFQDLMPEKIGSATTLYANTSRVGWIIAGSVDGIMVEIWSYHALFWLAIGMLGIAMI
                     CLLFIKDI"
     gene            794..1717
                     /locus_tag="RN951_001229"
     CDS             794..1717
                     /locus_tag="RN951_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDX2526260.1"
                     /translation="MGSTRKGMLNVLIAAVLWGSSGVCAQYIMEQSQMSSQFLTMTRL
                     IFAGLILLTLSFVHGDKIFSIINNHKDAISLLIFSVVGALTVQLTFLLTIEKSNAATA
                     TVLQFLSPTIIVAWFSLVRKSRPGILVFCAILTSLVGTFLLVTHGNPTSLSISPAALF
                     WGIASAFAAAFYTTYPSTLIARYGTLPVVGWSMLIGGLILLPFYARQGTNFVVNGSLI
                     LAFFYLVVIGTSLTFSLYLKGAQLIGGPKASILSCAEPLSSALLSLLLLGITFTLPDW
                     LGTLLILSSVILISMDSRRRARKINRPARHK"
     gene            complement(1721..2539)
                     /gene="nlpA"
                     /locus_tag="RN951_001230"
     CDS             complement(1721..2539)
                     /gene="nlpA"
                     /locus_tag="RN951_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein NlpA"
                     /protein_id="HDX2526261.1"
                     /translation="MKLTTHHLRTGAALLLAGILLAGCDQSSSDAKHIKVGVINGAEQ
                     DVAEVAKKVAKEKYGLDVELVGFSGSLLPNDATNHGELDANVFQHRPFLEQDNQAHGY
                     KLVAVGNTFVFPMAGYSKKIKTVAQIKEGATVAIPNDPTNLGRALLLLQKEKLITLKE
                     GKGLLPTALDITDNPRHLQIMELEGAQLPRVLDDPKVDVAIISTTYIQQTGLSPVHDS
                     VFIEDKNSPYVNILVAREDNKNAENVKEFLQSYQSPEVAKAAETIFNGGAVPGW"
     gene            2761..3054
                     /locus_tag="RN951_001231"
     CDS             2761..3054
                     /locus_tag="RN951_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526262.1"
                     /translation="MKPTTLLLIFTFFAMPGIVYAESPFSSLQSAKEKTTVLQDLRKI
                     CTPQASLSDEAWEKLMLSDENNKQHIREAIVAMERNNQSNYWEALGKVECPDM"
     gene            complement(3095..4285)
                     /gene="nepI"
                     /locus_tag="RN951_001232"
     CDS             complement(3095..4285)
                     /gene="nepI"
                     /locus_tag="RN951_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418118.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine ribonucleoside efflux pump NepI"
                     /protein_id="HDX2526263.1"
                     /translation="MSEFIAENRGADAITRPNWSAVFSVAFCVACLIIVEFLPVSLLT
                     PMAQDLGISEGVAGQSVTVTAFVAMFASLFITQTIQATDRRYVVILFAVLLTLSCLLV
                     SFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKALSVIFGAVSIALVIA
                     APLGSFLGELIGWRNVFNAAAVMGVLCIFWIIKSLPSLPGEPSHQKQNTFRLLQRPGV
                     MAGMIAIFMSFAGQFAFFTYIRPVYMNLAGFGVDGLTLVLLSFGIASFIGTSLSSFIL
                     KRSVKLALAGAPLILAVSALVLTLWGSDKIVATGVAIIWGLTFALVPVGWSTWITRSL
                     ADQAEKAGSIQVAVIQLANTCGAAIGGYALDNIGLTSPLMLSGTLMLLTALLVTAKVK
                     MKKS"
     gene            complement(4496..4948)
                     /locus_tag="RN951_001233"
     CDS             complement(4496..4948)
                     /locus_tag="RN951_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418119.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1198 domain-containing protein"
                     /protein_id="HDX2526264.1"
                     /translation="MIWIMLATLAVVFVVGFRVLTSGARKAIRRLSDRLNIDVVPVES
                     MVDQMGKSAGDEFLRYLHRPDESHLQNAAQVLLIWQIVIVDGSEQNLLQWHRILQKAR
                     LAAPITDAQVRLALGFLRETEPEMQDINAFQMRYNAFFQPAEGVHWLH"
     gene            complement(5001..6335)
                     /gene="adeQ"
                     /locus_tag="RN951_001234"
                     /gene_synonym="yicO"
     CDS             complement(5001..6335)
                     /gene="adeQ"
                     /locus_tag="RN951_001234"
                     /gene_synonym="yicO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine permease AdeQ"
                     /protein_id="HDX2526265.1"
                     /translation="MNNDNTDYVSNESGTLSRLFKLPQHGTTVRTELIAGMTTFLTMV
                     YIVFVNPQILGAAQMDPKVVFVTTCLIAGIGSIAMGIFANLPVALAPAMGLNAFFAFV
                     VVGAMGISWQTGMGAIFWGAVGLFLLTLFRIRYWMISNIPLSLRIGITSGIGLFIALM
                     GLKNTGVIVANKDTLVMIGDLSSHGVLLGILGFFIITVLSSRHFHAAVLVSIVVTSCC
                     GLFFGDVHFSGVYSIPPDISGVIGEVDLSGALTLELAGIIFSFMLINLFDSSGTLIGV
                     TDKAGLIDGNGKFPNMNKALYVDSVSSVAGAFIGTSSVTAYIESTSGVAVGGRTGLTA
                     VVVGVMFLLVMFFSPLVAIVPPYATAGALIFVGVLMTSSLARVNWDDFTESVPAFITT
                     VMMPFTFSITEGIALGFMSYCIMKVCTGRWRDLNLCVVVVAALFALKIILVD"
     gene            6510..8276
                     /gene="adeD"
                     /locus_tag="RN951_001235"
     CDS             6510..8276
                     /gene="adeD"
                     /locus_tag="RN951_001235"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HDX2526266.1"
                     /translation="MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLIN
                     GGEISGPIVIKGRYIAGVGAEYTDAPALQRIDARGATAVPGFIDAHLHIESSMMTPVT
                     FETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCD
                     VNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGL
                     GGKELNAYITAGIENCHESYQLEEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNS
                     PQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGL
                     LAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESARLAQSAPPYGNTIARQP
                     VSASDFALQFTPGKRYRVIDVIHNELITHSHSSVYSENGFDRDDVSFIAVLERYGQRL
                     APACGLLGGFGLNEGALAATVSHDSHNIVVIGRSAEEMALAVNQVIQDGGGLCVVRNG
                     QVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSLPVIPAL
                     KLTSQGLFDGEKFAFTTLEVTE"
     gene            complement(8322..9713)
                     /gene="uhpT"
                     /locus_tag="RN951_001236"
     CDS             complement(8322..9713)
                     /gene="uhpT"
                     /locus_tag="RN951_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose-6-phosphate:phosphate antiporter"
                     /protein_id="HDX2526267.1"
                     /translation="MLAFLNQVRKPTLDLPLEVRRKMWFKPFMQSYLVVFIGYLTMYL
                     IRKNFNIAQNDMISTYGLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFML
                     ILSAICMLGFSASMGSGSVSLFLMIAFYALSGFFQSTGGSCSYSTITKWTPRRKRGTF
                     LGFWNISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRYGSDSPE
                     SYGLGKAEELFGEEISEEDKETESTDMTKWQIFVEYVLKNKVIWLLCFANIFLYVVRI
                     GIDQWSTVYAFQELKLSKAVAIQGFTLFEAGALVGTLLWGWLSDLANGRRGLVACIAL
                     ALIIATLGVYQHASNEYIYLASLFALGFLVFGPQLLIGVAAVGFVPKKAIGAADGIKG
                     TFAYLIGDSFAKLGLGMIADGTPVFGLTGWAGTFAALDIAAIGCICLMAIVAVMEERK
                     IRREKKIQQLTVA"
     gene            complement(9851..11170)
                     /gene="uhpC"
                     /locus_tag="RN951_001237"
     CDS             complement(9851..11170)
                     /gene="uhpC"
                     /locus_tag="RN951_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418123.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter family glucose-6-phosphate
                     receptor UhpC"
                     /protein_id="HDX2526268.1"
                     /translation="MLPFLKAPADAPLMTDKYEIDARYRYWRRHILLTIWLGYALFYF
                     TRKSFNAAVPEILANGVLSRSDIGLLATLFYITYGVSKFVSGIVSDRSNARYFMGIGL
                     IATGIINILFGFSTSLWAFAVLWVLNAFFQGWGSPVCARLLTAWYSRTERGGWWALWN
                     TAHNVGGALIPIVMAAAALHYGWRAGMMIAGCMAIVVGIFLCWRLRDRPQALGLPAVG
                     EWRHDALEIAQQQEGAGLTRKEILTKYVLLNPYIWLLSFCYVLVYVVRAAINDWGNLY
                     MSETLGVDLVTANTAVTMFELGGFIGALVAGWGSDKLFNGNRGPMNLIFAAGILLSVG
                     SLWLMPFASYVMQATCFFTIGFFVFGPQMLIGMAAAECSHKEAAGAATGFVGLFAYLG
                     ASLAGWPLAKVLDTWHWSGFFVVISIAAGISALLLLPFLNAQTPREA"
     gene            complement(11180..12682)
                     /gene="uhpB"
                     /locus_tag="RN951_001238"
     CDS             complement(11180..12682)
                     /gene="uhpB"
                     /locus_tag="RN951_001238"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418124.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction histidine-protein
                     kinase/phosphatase UhpB"
                     /protein_id="HDX2526269.1"
                     /translation="MKTLFSRLITVIACFFIFSAAWFCLWSISLHLVERPDMAVLLFP
                     FGLRLGLMLQCPRGYWPVLLGAEWLLIYWLTQAVGLTHFPLLMIGSLLTLLPVALISR
                     YRHQRDWRTLLLQGAALTAAALLQSLPWLWHGKESWNALLLTLTGGLTLAPICLVFWH
                     YLANNTWLPLGPSLVSQPINWRGRHLVWYLLLFVISLWLQLGLPDELSRFTPFCLALP
                     IIALAWHYGWQGALIATLMNAIALIASQTWRDHPVDLLLSLLVQSLTGLLLGAGIQRL
                     RELNQSLQKELARNQHLAERLLETEESVRRDVARELHDDIGQTITAIRTQAGIVQRLA
                     ADNASVKQSGQLIEQLSLGVYDAVRRLLGRLRPRQLDDLTLEQAIRSLMREMELEGRG
                     IVSHLEWRIDESALSENQRVTLFRVCQEGLNNIVKHADASAVTLQGWQQDERLMLVIE
                     DDGSGLPPGSGQQGFGLTGMRERVTALGGTLHISCLHGTRVSVSLPQRYV"
     gene            complement(12682..13272)
                     /gene="uhpA"
                     /locus_tag="RN951_001239"
     CDS             complement(12682..13272)
                     /gene="uhpA"
                     /locus_tag="RN951_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator UhpA"
                     /protein_id="HDX2526270.1"
                     /translation="MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLP
                     GRGVQVCICDISMPDISGLELLSQLPKGMATIMLSVHDSPALVEQALNAGARGFLSKR
                     CSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
                     ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW"
     gene            complement(13348..13638)
                     /gene="ilvN"
                     /locus_tag="RN951_001240"
     CDS             complement(13348..13638)
                     /gene="ilvN"
                     /locus_tag="RN951_001240"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HDX2526271.1"
                     /translation="MQNTTHDNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPI
                     QDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQRNQSDPTMFNKIAVFFQ"
     gene            complement(13642..15330)
                     /gene="ilvB"
                     /locus_tag="RN951_001241"
     CDS             complement(13642..15330)
                     /gene="ilvB"
                     /locus_tag="RN951_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HDX2526272.1"
                     /translation="MASSGTTSTRKRFTGAEFIVHFLEQQGIKIVTGIPGGSILPVYD
                     ALSQSTQIRHILARHEQGAGFIAQGMARTDGKPAVCMACSGPGATNLVTAIADARLDS
                     IPLICITGQVPASMIGTDAFQEVDTYGISIPITKHNYLVRHIEELPQVMSDAFRIAQS
                     GRPGPVWIDIPKDVQTAVFEIETQPAMAEKAAAPAFSEESIRDAAAMINAAKRPVLYL
                     GGGVINAPARVRELAEKAQLPTTMTLMALGMLPKAHPLSLGMLGMHGVRSTNYILQEA
                     DLLIVLGARFDDRAIGKTEQFCPNAKIIHVDIDRAELGKIKQPHVAIQADVDDVLAQL
                     IPLVEAQPRAEWHQLVADLQREFPCPIPKACDPLSHYGLINAVAACVDDNAIITTDVG
                     QHQMWTAQAYPLNRPRQWLTSGGLGTMGFGLPAAIGAALANPDRKVLCFSGDGSLMMN
                     IQEMATASENQLDVKIILMNNEALGLVHQQQSLFYEQGVFAATYPGKINFMQIAAGFG
                     LETCDLNNEADPQASLQEIINRPGPALIHVRIDAEEKVYPMVPPGAANTEMVGE"
     gene            complement(15436..15534)
                     /gene="ivbL"
                     /locus_tag="RN951_001242"
     CDS             complement(15436..15534)
                     /gene="ivbL"
                     /locus_tag="RN951_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ilvB operon leader peptide IvbL"
                     /protein_id="HDX2526273.1"
                     /translation="MTTSMLNAKLLPTAPSAAVVVVRVVVVVGNAP"
     gene            16099..16188
                     /gene="tisB"
                     /locus_tag="RN951_001243"
     CDS             16099..16188
                     /gene="tisB"
                     /locus_tag="RN951_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin TisB"
                     /protein_id="HDX2526274.1"
                     /translation="MNLVDIAILILKLIVAALQLLDAVLKYLK"
     gene            16468..17652
                     /gene="emrD"
                     /locus_tag="RN951_001244"
     CDS             16468..17652
                     /gene="emrD"
                     /locus_tag="RN951_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418129.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EmrD"
                     /protein_id="HDX2526275.1"
                     /translation="MKRQRNVNLLLMLVLLVAVGQMAQTIYIPAIADMARDLNVREGA
                     VQSVMGAYLLTYGVSQLFYGPISDRVGRRPVILVGMSIFMLATLVAVTTSSLTVLIAA
                     SAMQGMGTGVGGVMARTLPRDLYERTQLRHANSLLNMGILVSPLLAPLIGGLLDTMWN
                     WRACYLFLLVLCAGVTFSMARWMPETRPVDAPRTRLLTSYKTLFGNSGFNCYLLMLIG
                     GLAGIAAFEACSGVLMGAVLGLSSMTVSILFILPIPAAFFGAWFAGRPNKRFSTLMWQ
                     SVICCLLAGLLMWIPDWFGVMNVWTLLVPAALFFFGAGMLFPLATSGAMEPFPFLAGT
                     AGALVGGLQNIGSGVLASLSAMLPQTGQGSLGLLMTLMGLLIVLCWLPLATRMSHQGQ
                     PV"
     gene            complement(17660..18157)
                     /locus_tag="RN951_001245"
     CDS             complement(17660..18157)
                     /locus_tag="RN951_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDX2526276.1"
                     /translation="MTGSQVIDAEEDRHKLVVEYKDALQPADFYHNFKQRGIRSVQLI
                     PYLEFDDRGDLTAASVTAELWGKFLIALFECWVRADISRISIELFDATLQKWCGSENP
                     QPRCDCQACDWHRLCPHARQETPDSVLCAGYQAFYSYSAPHMRVMRDLIKQHRSPMEL
                     MTMLR"
     gene            complement(18154..18516)
                     /locus_tag="RN951_001246"
     CDS             complement(18154..18516)
                     /locus_tag="RN951_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF202 domain-containing protein"
                     /protein_id="HDX2526277.1"
                     /translation="MPDSRKARRIADPGLQPERTSLAWFRTMLGYGALMALAIKHNWH
                     QAGMLFWISIGILAIVALILWHYTRNRNLMDVTNSDFSQFHVVRDKFLISLAVLSLAI
                     LFAVTHIHQLIVFIERVA"
     gene            complement(18506..18853)
                     /locus_tag="RN951_001247"
     CDS             complement(18506..18853)
                     /locus_tag="RN951_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidH family protein"
                     /protein_id="HDX2526278.1"
                     /translation="MKISRLGEAPDYRFSLANERTFLAWIRTALGFLAAGVGLDQLAP
                     DFATPVIRELLALLLCLFSGGLAMYGYLRWLRNEKAMRLKEDLPYTNSLLIISLILMV
                     VAVIVMGLVLYAG"
     gene            18961..19410
                     /locus_tag="RN951_001248"
     CDS             18961..19410
                     /locus_tag="RN951_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526279.1"
                     /translation="MGIIAQNKISSLGMLFGAIALMMGIIHFSFGPFSAPPPTFESIV
                     ADKTAEIKRGLLAGIKGEKITTVEKKEDVDVDKILNQSGIALAIAALLCAFIGGMRKE
                     NRWGIRGALVFGGGTLAFHTLLFGIGIVCSILLIFLIFSFLTGGSLV"
     gene            complement(19457..20950)
                     /locus_tag="RN951_001249"
     CDS             complement(19457..20950)
                     /locus_tag="RN951_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HDX2526280.1"
                     /translation="MKRPNFLFVMTDTQATNMVGCYSGKPLNTQNIDSLAAEGIRFNS
                     AYTCSPVCTPARAGLFTGIYANQSGPWTNNVAPGKNISTMGRYFKDAGYHTCYIGKWH
                     LDGHDYFGTGECPPEWDADYWFDGANYLSELTEKEISLWRNGLNSVEDLQANHIDETF
                     TWAHRISNRAVDFLQQPARADEPFLMVVSYDEPHHPFTCPVEYLEKYADFYYELGEKA
                     QDDLANKPEHHRLWAQAMPSPVGDDGLYHHPLYFACNDFVDDQIGRVINALTPEQREN
                     TWVIYTSDHGEMMGAHKLISKGAAMYDDITRIPLIIRSPQGERRQVDTPVSHIDLLPT
                     MMALADIEKPEILPGENILAVKEPRGVMVEFNRYEIEHDSFGGFIPVRCWVTDDFKLV
                     LNLFTSDELYDRRNDPNEMHNLIDDIRFADVRSKMHDALLDYMDKIRDPFRSYQWSLR
                     PWRKDARPRWMGAFRPRPQDGYSPVVRDYDTGLPTQGVKVEEKKQKF"
     gene            complement(20947..22662)
                     /locus_tag="RN951_001250"
     CDS             complement(20947..22662)
                     /locus_tag="RN951_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HDX2526281.1"
                     /translation="MNSLQILSFVGFTLLVAVITWWKVRKTDTGSQQGYFLAGRSLKA
                     PVIAASLMLTNLSTEQLVGLSGQAYKSGMSVMGWEVTSAVTLIFLALIFLPRYLKRGI
                     ATIPDFLEERYDKTTRIIIDFCFLIATGVCFLPIVLYSGALALNSLFHVGESLQISHG
                     AAIWLLVILLGLAGILYAVIGGLRAMAVADSINGIGLVIGGLMVPVFGLIAMGKGSFM
                     QGIEQLTTVHAEKLNSIGGPTDPLPIGAAFTGLILVNTFYWCTNQGIVQRTLASKSLA
                     EGQKGALLTAVLKMLDPLVLVLPGLIAFHLYQDLPKADMAYPTLVNNVLPVPMVGFFG
                     AVLFGAVISTFNGFLNSASTLFSMGIYRRIINQNAEPQQLVTVGRKFGFFIAIVSVLV
                     APWIANAPQGLYSWMKQLNGIYNVPLVTIIIMGFFFPRIPALAAKVAMGIGIISYITI
                     NYLVKFDFHFLYVLACTFCINVVVMLVIGFIKPRATPFTFKDAFAVDMKPWKNVKIAS
                     IGILFAMIGVYAGLAEFGGYGTRWLAMISYFIAAVVIVYLIFDSWRHRHDPAVTFTPD
                     GKDSL"
     gene            22829..23722
                     /locus_tag="RN951_001251"
     CDS             22829..23722
                     /locus_tag="RN951_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418136.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDX2526282.1"
                     /translation="MNGKLQSSDVKNETPYNIPLLINENVISSGISLISLWHTYADEH
                     YRVIWPRDKKKPLIANSWVAVYTVQGCGKILLKNGEQITLHGNCIIFLKPMDIHSYHC
                     EGLVWEQYWMEFTPTSMMDIPVGQQSVIYNGEIYNQELTEVAELITSPEAIKNNLAVA
                     FLTKIIYQWICLMYADGKKDPQRRQIEKLIATLHASLQQRWSVADMAATIPCSEAWLR
                     RLFLRYTGKTPKEYYLDARLDLALSLLKQQGNSVGEVADTLNFFDSFHFSKAFKHKFG
                     YAPSAVLKNTDQHPTDASPHN"
     gene            complement(23719..24533)
                     /locus_tag="RN951_001252"
                     /pseudo
     CDS             complement(23719..24533)
                     /locus_tag="RN951_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312649.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(24533..26149)
                     /locus_tag="RN951_001253"
     CDS             complement(24533..26149)
                     /locus_tag="RN951_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312650.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDX2526283.1"
                     /translation="MLSQIQRFGGAMFTPVLLFPFAGIVVGLAILLQNPMFVGESLTD
                     PNSLFAQIVHIIEEGGWTVFRNMPLIFAVGLPIGLAKQAQGRACLAVMVSFLTWNYFI
                     NAMGMTWGSYFGVDFTQDAVAGSGLTMMAGIKTLDTSIIGAIIISGIVTALHNRLFDK
                     KLPVFLGIFQGTSYVVIIAFLVMIPCAWLTLLGWPKVQMGIESLQAFLRSAGALGVWV
                     YTFLERILIPTGLHHFIYGQFIFGPAAVEGGIQMYWAQHLQEFSLSAEPLKSLFPEGG
                     FALHGNSKIFGAVGISLAMYFTAAPENRVKVAGLLIPATLTAMLVGITEPLEFTFLFI
                     SPLLFAVHAVLAASMSTVMYLFGVVGNMGGGLIDQVLPQNWIPMFSNHADMMLTQIAI
                     GLCFTLLYFVVFRTLILQFNMCTPGREDAEVKLYSKAEYKASRGQTTAAEPKKELDQA
                     AGILQALGGVGNISSINNCATRLRIALHDMSQTLDDEVFKKLGAHGVFRSGDAIQVII
                     GLHVSQLREQLDSLINSHQSAENVAITEAV"
     gene            26445..27161
                     /locus_tag="RN951_001254"
     CDS             26445..27161
                     /locus_tag="RN951_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDX2526284.1"
                     /translation="MIYKSIAERLRIRLNSADFTLNSLLPGEKKLAEEFAVSRMTIRK
                     AIDLLVAWGLVVRRHGSGTYLVRKDVLHQTASLTGLVEVLKRQGKTVTSQVLIFEIMP
                     APPAIASQLRIQINEQIYFSRRVRFVEGKPLMLEDSYMPVKLFRNLSLQHLEGSKFEY
                     IEQECGILIGGNYESLTPVLADRLLARQMKVAEHTPLLRITSLSYSESGEFLNYSVMF
                     RNASEYQVEYHLRRLHPEKS"
     gene            complement(27158..28819)
                     /locus_tag="RN951_001255"
     CDS             complement(27158..28819)
                     /locus_tag="RN951_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312652.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transporter"
                     /protein_id="HDX2526285.1"
                     /translation="MSDIALTVSILALVAVVGLFIGNVKFRGIGLGIGGVLFGGIIVG
                     HFVSQAGMTLSSDMLHVIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNLFAVLIVI
                     IGGLVTAILHKLFDIPLPVVLGIFSGAVTNTPALGAGQQILRDLGTPMEMVDQMGMSY
                     AMAYPFGICGILFTMWMLRVIFRVNVETEAQQHESSRTNGGALIKTINIRVENPNLHD
                     LAIKDVPILNGDKIICSRLKREETLKVPSPDTIIQLGDLLHLVGQPADLHNAQLVIGQ
                     EVDTSLSTKGTDLRVERVVVTNENVLGKRIRDLHFKERYDVVISRLNRAGVELVASGD
                     ISLQFGDILNLVGRPSAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPVFVP
                     GFPAALKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLSVVGLKS
                     GGDFVNTLVNGEGLSWIGYGALITAVPLITVGILARMLAKMNYLTMCGMLAGSMTDPP
                     ALAFANNLHPTSGAAALSYATVYPLVMFLRIITPQLLAVLFWSIG"
     gene            complement(29015..29443)
                     /gene="ibpB"
                     /locus_tag="RN951_001256"
     CDS             complement(29015..29443)
                     /gene="ibpB"
                     /locus_tag="RN951_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709512.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock chaperone IbpB"
                     /protein_id="HDX2526286.1"
                     /translation="MRNFDLSPLMRQWIGFDKLANALQNAGESQSFPPYNIEKSDDNH
                     YRITLALAGFRQEDLEIQLEGTRLSVKGTPEQPKEEKKWLHQGLMNQPFSLSFTLAEN
                     MEVSGATFVNGLLHIDLIRNEPEPIAAQRIAISERPALNS"
     gene            complement(29555..29968)
                     /gene="ibpA"
                     /locus_tag="RN951_001257"
     CDS             complement(29555..29968)
                     /gene="ibpA"
                     /locus_tag="RN951_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006687722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock chaperone IbpA"
                     /protein_id="HDX2526287.1"
                     /translation="MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDE
                     NHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLA
                     ENIHVRGANLVNGLLYIDLERVIPEAKKPRRIEIN"
     misc_feature    complement(29962..30034)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01832"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ROSE (Repression Of Heat Shock gene Expression)
                     occurs in the 5'-region of heat shock genes and acts as an
                     RNA thermometer to modulate expression; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF01832"
     gene            30274..30606
                     /locus_tag="RN951_001258"
     CDS             30274..30606
                     /locus_tag="RN951_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418143.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HDX2526288.1"
                     /translation="MIRNVLLAFMICSGMTLLGGCSSVMSHTGGKEGTYPGTRASATM
                     IGDDETNWGTKSLAILDMPFTAVMDTLLLPWDVFRKDSSVRSRVEKSEANAQATNAVI
                     PPARMPDN"
     gene            complement(30608..31822)
                     /locus_tag="RN951_001259"
     CDS             complement(30608..31822)
                     /locus_tag="RN951_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312656.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3748 domain-containing protein"
                     /protein_id="HDX2526289.1"
                     /translation="MKQITFAPRNHLLTNTNTWTPDSQWLVFDVRPSGASFTGETIER
                     VNIHTGEVEVIYRASQGAHVGVVTVHPKSEKYVFIHGPENPDETWHYDFHHRRGVIVE
                     GGKMSNLDAMDITAPYTPGVLRGGSHVHVFSPNGERVSFTYNDHVMHELDPALDLRNV
                     GVAAPFGPVNVQKQHPREYSGSHWCVLVSKTTPTPQPGSDEINRAYEEGWVGNHALAF
                     IGDTLSPKGEKVPELFIVELPQDEAGWKAAGDAPLSGTETTLPAPPRGVVQRRLTFTH
                     HRAYPGLVNVPRHWVRCNPQGTQIAFLMRDDNGIVQLWLISPQGGEPRQLTHNKTDIQ
                     SAFNWHPSGEWLGFVLDNRIACAHAQSGEVEYLTEHHANSPSADAVVFSPDGQWLAWM
                     EGGQLWITETDR"
     gene            31923..32987
                     /gene="cbrA"
                     /locus_tag="RN951_001260"
                     /pseudo
     CDS             31923..32987
                     /gene="cbrA"
                     /locus_tag="RN951_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418145.2"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="colicin M resistance protein"
     gene            complement(32984..34321)
                     /locus_tag="RN951_001261"
     CDS             complement(32984..34321)
                     /locus_tag="RN951_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2526290.1"
                     /translation="MVSGFAMPKIWRKLAMDIPVNAAKPGRRRYLTLVMIFITVVICY
                     VDRANLAVASAHIQEEFGITKAEMGYVFSAFAWLYTLCQIPGGWFLDRVGSRVTYFIA
                     IFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFY
                     TSGQFVGLAFLTPLLIWIQEMLNWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKA
                     ELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHRKLIGVYLGQFAVASTLWFFLT
                     WFPNYLTQEKGITALKAGFMTTVPFLAAFVGVLLSGWVADLLVRKGFSLGFARKTPII
                     CGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLTGGVF
                     NFAGGLGGITVPLVVGYLAQGYGFAPALVYISAVALIGALSYILLVGDVKRVG"
     gene            complement(34396..35544)
                     /gene="dgoD"
                     /locus_tag="RN951_001262"
     CDS             complement(34396..35544)
                     /gene="dgoD"
                     /locus_tag="RN951_001262"
                     /EC_number="4.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020077623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
                     /protein_id="HDX2526291.1"
                     /translation="MKITKITTYRLPPRWMFLKIETDEGVVGWGEPVIEGRARTVEAA
                     VHELGDYLIGQDPSRINDLWQVMYRAGFYRGGPILMSAIAGIDQALWDIKGKVLNAPV
                     WQLMGGLVRDKIKAYSWVGGDRPADVIDGIKTLREIGFDTFKLNGCEELGLIDNSRAV
                     DAAVNTVAQIREAFGNQIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAE
                     YYPKLAAQTHIPLAAGERMFSRFDFKRVLEAGGISILQPDLSHAGGITECYKIAGMAE
                     AYDVTLAPHCPLGPIALAACLHIDFVSYNAVLQEQSMGIHYNKGAELLDFVKNKEDFS
                     MVGGFFKPLTKPGLGVEIDEAKVIEFSKNAPDWRNPLWRHEDNSVAEW"
     gene            complement(35541..36158)
                     /gene="dgoA"
                     /locus_tag="RN951_001263"
     CDS             complement(35541..36158)
                     /gene="dgoA"
                     /locus_tag="RN951_001263"
                     /EC_number="4.1.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-6-phosphogalactonate aldolase"
                     /protein_id="HDX2526292.1"
                     /translation="MQWQTKLPLIAILRGITPDEALAHVGAVIDAGFDAVEIPLNSPQ
                     WEQSIPAIVDAYGDKALIGAGTVLKPEQVDALARMGCQLIVTPNIHSEVIRRAVGYGM
                     TVCPGCATATEAFTALEAGAQALKIFPSSAFGPQYIKALKAVLPSDIAVFAVGGVTPE
                     NLAQWIDAGCAGAGLGSDLYRAGQSVERTAQQAAAFVKAYREAVQ"
     gene            complement(36142..37020)
                     /gene="dgoK"
                     /locus_tag="RN951_001264"
     CDS             complement(36142..37020)
                     /gene="dgoK"
                     /locus_tag="RN951_001264"
                     /EC_number="2.7.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygalactonokinase"
                     /protein_id="HDX2526293.1"
                     /translation="MTARYIAIDWGSTNLRAWLYQGDHCLESRQSEAGVTRLNGKSPA
                     AVLAEVTTDWREEKTPVVMAGMVGSNVGWKVAPYLSVPACFSSIGEQLTSVGDNIWII
                     PGLCVSHDDNHNVMRGEETQLIGARALAPSSLYVMPGTHCKWVQADSQQINDFRTVMT
                     GELHHLLLNHSLIGAGLPPQENSADAFTAGLERGLNTPAILPQLFEVRASHVLGTLPR
                     EQVSEFLSGLLIGAEVASMRDYVAHQHAITLVAGTSLTARYQQAFQAMGCDVTAVAGD
                     TAFQAGIRSIAHAVAN"
     gene            complement(37017..37706)
                     /gene="dgoR"
                     /locus_tag="RN951_001265"
     CDS             complement(37017..37706)
                     /gene="dgoR"
                     /locus_tag="RN951_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-galactonate utilization transcriptional
                     regulator DgoR"
                     /protein_id="HDX2526294.1"
                     /translation="MTLNKTDRIVITLGKQIVHGKYVPGSPLPAEAELCEEFATSRNI
                     IREVFRSLMAKRLIEMKRYRGAFVAPRNQWNYLDTDVLQWVLENDYDPRLISAMSEVR
                     NLVEPAIARWAAERATSSDLAQIESALNEMIANNQDREAFNEADIRYHEAVLQSVHNP
                     VLQQLSIAISSLQRAVFERTWMGDEANMPQTLQEHKALFDAIRHQDGDAAEQAALTMI
                     ASSTRRLKEIT"
     gene            37984..38640
                     /locus_tag="RN951_001266"
     CDS             37984..38640
                     /locus_tag="RN951_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526295.1"
                     /translation="MKLNFKGFFKAAGLFPLALMLSGCISYALVSHTAKGSSGKYQSQ
                     SDTITGLSQAKDSNGTKGYVFVGESLDYLITDGADDIVKMLNDPALNRHNIQVADDAR
                     FVLNAGKKKFTGTISLYYYWNNEEEKALATHYGFACGVQHCTRSLENLKGTIHEKNKN
                     MDYSKVMAFYHPFKVRFYEYYSPRGIPDGVSAALLPVTVTLDIITAPLQFLVVYAVNQ
                     "
     gene            complement(38686..39498)
                     /gene="yidA"
                     /locus_tag="RN951_001267"
     CDS             complement(38686..39498)
                     /gene="yidA"
                     /locus_tag="RN951_001267"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HDX2526296.1"
                     /translation="MAIKLIAIDMDGTLLLPDHTISPAVKNAIAAARARGVNVVLTTG
                     RPYAGVHNYLKELHMEQPGDYCITYNGALVQKAADGSTVAQTALSYDDYRFLEKLSRE
                     VGSHFHALDRTTLYTANRDISYYTVHESFVATIPLVFCEAEKMDPNTQFLKVMMIDEP
                     AILDQAIARIPQEVKEKYTVLKSAPYFLEILDKRVNKGTGVKSLADVLGIKPEEIMAI
                     GDQENDIAMIEYAGVGVAMDNAIPSVKEVANFVTKSNLEDGVAFAIEKYVLN"
     gene            complement(39613..40011)
                     /locus_tag="RN951_001268"
     CDS             complement(39613..40011)
                     /locus_tag="RN951_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418153.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidB family protein"
                     /protein_id="HDX2526297.1"
                     /translation="MGLFDEVVGAFLKGDAGKYQAILSWVEEQGGIQVLLEKLQSGGL
                     GAILSTWLSNQQGNQSVSGEQLESALGTNAVSDLGQKLGVDTSTASSLLAEQLPKIID
                     ALSPQGEVSPQANNDLLSAGMELLKGKLFR"
     gene            complement(40251..42665)
                     /gene="gyrB"
                     /locus_tag="RN951_001269"
     CDS             complement(40251..42665)
                     /gene="gyrB"
                     /locus_tag="RN951_001269"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HDX2526298.1"
                     /translation="MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVV
                     DNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHAGG
                     KFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGET
                     EKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHY
                     EGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQR
                     DGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLIAVVSVKVPDPKFSS
                     QTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMT
                     RRKGALDLAGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKI
                     LNVEKARFDKMLSSQEVATLITALGCGIGRDEYNPDKLRYHSIIIMTDADVDGSHIRT
                     LLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATL
                     HTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQ
                     TVTRWVNALVSELNDKEQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFI
                     TGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYK
                     GLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALK
                     AANIDI"
     gene            complement(42694..43767)
                     /gene="recF"
                     /locus_tag="RN951_001270"
     CDS             complement(42694..43767)
                     /gene="recF"
                     /locus_tag="RN951_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HDX2526299.1"
                     /translation="MSLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIY
                     TLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDG
                     HKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFTAWSNLKRLLKQ
                     RNAALRQVTRYEQLRPWDKELIPLAEQISTWRAEYSAGIAADMADTCKQFLPEFSLTF
                     SFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKL
                     LMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISA
                     EHVIDMSDENSKMFTVEKGKITD"
     gene            complement(43767..44867)
                     /gene="dnaN"
                     /locus_tag="RN951_001271"
     CDS             complement(43767..44867)
                     /gene="dnaN"
                     /locus_tag="RN951_001271"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006177590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HDX2526300.1"
                     /translation="MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSL
                     TGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSG
                     RSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLF
                     ETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQI
                     GSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNE
                     KFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCE
                     NVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL"
     gene            complement(44872..46275)
                     /gene="dnaA"
                     /locus_tag="RN951_001272"
     CDS             complement(44872..46275)
                     /gene="dnaA"
                     /locus_tag="RN951_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HDX2526301.1"
                     /translation="MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPN
                     RFVLDWVRDKYLNNINGLLTSFCGADAPQLRFEVGTKPVTQTPQAAVTSNVAAPAQVA
                     QTQPQRAAPSTRSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADN
                     PGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNA
                     IEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEIN
                     GVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVR
                     ELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVA
                     DLLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREE
                     SHDIKEDFSNLIRTLSS"
     gene            46572..46652
                     /locus_tag="RN951_001273"
     CDS             46572..46652
                     /locus_tag="RN951_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526302.1"
                     /translation="MTIDKNWLNRSNKDPGRSLRFTHQPV"
     gene            46882..47022
                     /gene="rpmH"
                     /locus_tag="RN951_001274"
     CDS             46882..47022
                     /gene="rpmH"
                     /locus_tag="RN951_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001686914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HDX2526303.1"
                     /translation="MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTV
                     SK"
     gene            47039..47398
                     /gene="rnpA"
                     /locus_tag="RN951_001275"
     CDS             47039..47398
                     /gene="rnpA"
                     /locus_tag="RN951_001275"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014172301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HDX2526304.1"
                     /translation="MVKLAFPRELRLLTPSQFTFVFQQPQRAGTPQITILGRLNSLGH
                     PRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALS
                     EALEKLWRRHCRLARGS"
     gene            47362..47619
                     /gene="yidD"
                     /locus_tag="RN951_001276"
     CDS             47362..47619
                     /gene="yidD"
                     /locus_tag="RN951_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HDX2526305.1"
                     /translation="MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEA
                     LRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH"
     gene            47622..49268
                     /gene="yidC"
                     /locus_tag="RN951_001277"
     CDS             47622..49268
                     /gene="yidC"
                     /locus_tag="RN951_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDX2526306.1"
                     /translation="MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAA
                     GSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLET
                     SPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNT
                     FTKTFVLKRGDYAVNVNYNVQNAGEKPLEISSFGQLKQSITLPPHLDTGSSNFALHTF
                     RGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYT
                     ANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLW
                     FISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQA
                     MRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAP
                     FALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLW
                     FPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS"
     gene            49374..50738
                     /gene="mnmE"
                     /locus_tag="RN951_001278"
     CDS             49374..50738
                     /gene="mnmE"
                     /locus_tag="RN951_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HDX2526307.1"
                     /translation="MSDNDTIVAQATPPGRGGVGILRISGFKAREVAETVLGKLPKPR
                     YADYLPFKDADGSVLDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTIPG
                     LRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLV
                     EALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNDVIADLDAVRAEARQGSLLREGMK
                     VVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRE
                     ASDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPAEIWPEFIARLPAKLPITVVR
                     NKADITGETLGMSEVNGHALIRLSARTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRH
                     LQALEQAAEHLQQGKAQLLGAWAGELLAEELRLAQQNLSEITGEFTSDDLLGRIFSSF
                     CIGK"
     gene            50981..51055
                     /gene="tnaC"
                     /locus_tag="RN951_001279"
     CDS             50981..51055
                     /gene="tnaC"
                     /locus_tag="RN951_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanase leader peptide"
                     /protein_id="HDX2526308.1"
                     /translation="MNILHICVTSKWFNIDNKIVDHRP"
     gene            51276..52691
                     /gene="tnaA"
                     /locus_tag="RN951_001280"
     CDS             51276..52691
                     /gene="tnaA"
                     /locus_tag="RN951_001280"
                     /EC_number="4.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709490.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanase"
                     /protein_id="HDX2526309.1"
                     /translation="MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSE
                     DVFIDLLTDSGTGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQG
                     RGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFD
                     TGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAK
                     KYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPM
                     GGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYR
                     IAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIR
                     AVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIK
                     GLTFTYEPKVLRHFTAKLKEV"
     gene            52782..54029
                     /gene="tnaB"
                     /locus_tag="RN951_001281"
     CDS             52782..54029
                     /gene="tnaB"
                     /locus_tag="RN951_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity tryptophan permease TnaB"
                     /protein_id="HDX2526310.1"
                     /translation="MTDQAEKKHSAFWGVMVIAGTVIGGGMFALPVDLAGAWFFWGAF
                     ILIIAWFSMLHSGLLLLEANLNYPVGSSFNTITKDLIGNTWNIISGITVAFVLYILTY
                     AYISANGAIISETISMNLGYHANPRIVGICTAIFVASVLWLSSLAASRITSLFLGLKI
                     ISFVIVFGSFFFQVDYSILRDATSSTAGTSYFPYIFMALPVCLASFGFHGNIPSLIIC
                     YGKRKDKLIKSVVFGSLLALVIYLFWLYCTMGNIPRESFKAIISSGGNVDSLVKSFLG
                     TKQHGIIEFCLLVFSNLAVASSFFGVTLGLFDYLADLFKIDNSHGGRFKTVLLTFLPP
                     ALLYLIFPNGFIYGIGGAGLCATIWAVIIPAVLAIKARKKFPNQMFTVWGGNLIPAIV
                     ILFGITVILCWFGNVFNVLPKFG"
     gene            54161..55336
                     /gene="mdtL"
                     /locus_tag="RN951_001282"
     CDS             54161..55336
                     /gene="mdtL"
                     /locus_tag="RN951_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtL"
                     /protein_id="HDX2526311.1"
                     /translation="MSRFLICSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAF
                     SVYLAGMAAAMLFAGKVADRSGRKPVAIPGAALFIIASVFCSLAETSTLFLAGRFLQG
                     LGAGCCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLF
                     WAMAMMGIAVLMLSLFILKETRPAAPAASDKPRENSESLLNRFFLSRVVITTLSVSVI
                     LTFVNTSPVLLMEIMGFERGEYATIMALTAGVSMTVSFSTPFALGIFKPRTLMITSQV
                     LFLAAGITLAVSPSHAVSLFGITLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIA
                     QVCGSSLWIWLAAVVGIGAWNMLIGILIACSIVSLLLIMFVAPGRPVAAHEEIHHHA"
     gene            55311..56270
                     /gene="yidZ"
                     /locus_tag="RN951_001283"
     CDS             55311..56270
                     /gene="yidZ"
                     /locus_tag="RN951_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator YidZ"
                     /protein_id="HDX2526312.1"
                     /translation="MKKSITTLDLNLLLCLQLLMQERSVTKAAKRINVTPSAVSKSLA
                     KLRAWFDDPLFVNSPLGLSPTPLMVSMEQNLAEWMQMSNLLLDKPHHQTPRGLKFELA
                     AESPLMMIMLNALSKQIYQRYPQATIKLRNWDYDSLDAITRGEVDIGFSGRESHPRSR
                     ELLSSLPLAIDYEVLFSDVPCVWLRKDHPALHQTWNLDTFLRYPHISICWEQSDTWAL
                     DNVLQELGRERTIAMSLPEFEQSLFMAAQPDNLLLATAPRYCQYYNQLHQLPLVALPL
                     PFDESQQKKLEVPFTLLWHKRNSHNPKIVWLRETIKNLYASMA"
     gene            56427..57176
                     /locus_tag="RN951_001284"
     CDS             56427..57176
                     /locus_tag="RN951_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="HDX2526313.1"
                     /translation="MATHFARGILTEGHLISVRLPSQCHQEARNIPPHRQSRFLASRG
                     LLAELMFMLYGIGELPEIVTLPKGKPVFSDKNLPSFSISYAGNMVGVALTTEGECGLD
                     MELQRATRGFHSPHAPDNHTFSSNESLWISKQNDPNEARAQLITLRRSVLKLTGDVLN
                     DDPRDLQLLPIAGRLKCAHVNHVEALCDAEDVLVWSVAVTPTIEKLSVWEFDGKHGWK
                     SLPDIHSRANNPTSRMMRFAQLSTVKAFSPN"
     gene            57198..57764
                     /gene="yieF"
                     /locus_tag="RN951_001285"
                     /gene_synonym="chrR"
     CDS             57198..57764
                     /gene="yieF"
                     /locus_tag="RN951_001285"
                     /gene_synonym="chrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I chromate reductase YieF"
                     /protein_id="HDX2526314.1"
                     /translation="MSEKLQVVTLLGSLRKGSFNGMVARTLPKIAPASMEVNALPSIA
                     DIPLYDADVQQEEGFPATVEALAEQIRQADGVVIVTPEYNYSVPGGLKNAIDWLSRLP
                     DQPLAGKPVLIQTSSMGVIGGARCQYHLRQILVFLDAMVMNKPEFMGGVIQNKVDPQT
                     GEVIDQGTLDHLTGQLTAFGEFIQRVKI"
     gene            complement(57818..59155)
                     /gene="adeP"
                     /locus_tag="RN951_001286"
     CDS             complement(57818..59155)
                     /gene="adeP"
                     /locus_tag="RN951_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine permease AdeP"
                     /protein_id="HDX2526315.1"
                     /translation="MSHQHTTQTSGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVY
                     IVFVNPQILGVAGMDTSAVFVTTCLIAAFGSIMMGLFANLPVALAPAMGLNAFFAFVV
                     VQAMGLPWQVGMGAIFWGAIGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMG
                     LKNAGVIVANPETLVSIGNLTSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLG
                     WMLGDVHYNGIVSAPPSVMTVVGHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVT
                     DKAGLADEKGKFPRMKQALYVDSISSVTGSFIGTSSVTAYIESSSGVSVGGRTGLTAV
                     VVGLLFLLVIFLSPLAGMVPGYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAV
                     MMPFSFSITEGIALGFISYCVMKIGTGRLRDLSPCVIIVALLFILKIVFIDAH"
     gene            59320..59985
                     /gene="yieH"
                     /locus_tag="RN951_001287"
     CDS             59320..59985
                     /gene="yieH"
                     /locus_tag="RN951_001287"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate phosphatase"
                     /protein_id="HDX2526316.1"
                     /translation="MSRIEAVFFDCDGTLVDSEVICSRAYVTMFQEFGITLDPEEVFK
                     RFKGVKLYEIIDIVSLEHGVTLAKTEAEHVYRAEVARLFDSELEAIEGAGALLSAITA
                     PMCVVSNGPNNKMQHSMGKLNMLHYFPDKLFSGYDIQRWKPDPALMFHAAKAMNVNVE
                     NCILVDDSVAGAQSGIDAGMEVFYFCADPHNKPIVHPKVTTFTHLSQLPELWKARGWD
                     ITA"
     gene            60052..60519
                     /locus_tag="RN951_001288"
     CDS             60052..60519
                     /locus_tag="RN951_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CbrB"
                     /protein_id="HDX2526317.1"
                     /translation="MSVSRRVIHHGLYFAVLGPLIGVLFLVLYIFFAKEPLVLWVIIH
                     PIFLLLSITTGAIPALLTGVMVACLPEKIGSQKRYRCLAGGIGGVVITEIYCAVIVHI
                     KGMASSELFENILSGDSLVVRIIPALLAGVVMSRIITRLPGLDISCPETDSLS"
     gene            60568..>60828
                     /locus_tag="RN951_001289"
     CDS             60568..>60828
                     /locus_tag="RN951_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CbrC family protein"
                     /protein_id="HDX2526318.1"
                     /translation="MTQNIRPLPQFKYHPKPLETGAFEQDKTVECDCCEQQTSVYYSG
                     PFYCVDEVEHLCPWCIADGSAAEKFAGSFQDDASIEGVEFEYD"
BASE COUNT        14953 a        16112 c        15350 g        14413 t
ORIGIN      
        1 gatttagttt taaagtgatg tatctcaccg ctgccatcgc atttgttgtt tgcggactga
       61 tagtctggtt gtttttgcca tcaatacaaa gaaatattcc tgtcgttacc caacccgtag
      121 aaattttacc ctccacccac aggaagcggg atacgcggct actttttgtg gtctgttcaa
      181 tgatgtgggc ggcgaataat ctctacatga taaatatgcc gctatttatt attgatgaac
      241 tgcatctaac cgataaactg gctggagaaa tgattggtat cgctgccggt ctggaaattc
      301 cgatgatgtt aatcgcaggc tattacatga aacgtattgg caagcgacta ttaatgctca
      361 ttgctatcgt gagtggaatg tgtttttacg ccagcgtact catggcgacg actccggcgg
      421 ttgagctgga attgcaaatt cttaatgcca tcttccttgg tattctctgt ggtatcggca
      481 tgctttattt tcaggacttg atgcctgaaa aaataggctc tgcgacaacg ttatatgcaa
      541 atacttcacg cgtcggctgg attatcgccg gctctgttga cggaattatg gttgaaatct
      601 ggagctacca tgcgttgttc tggctggcga tagggatgtt gggtattgcg atgatttgcc
      661 tgctgtttat taaagatatt tagctcacca gtctgggcta agaaaaatcg gcgtggcgca
      721 aacagagcca tcctcgccat ttttgctatc atgcctgcat acataaacga caaaacagta
      781 tgcagaggga aaaatgggtt ccaccagaaa ggggatgctg aacgttctga ttgccgccgt
      841 gttgtgggga agttcagggg tctgcgcgca atacatcatg gagcaaagcc agatgtcgtc
      901 gcagtttttg actatgacgc gtttgatatt cgccggtttg attctactga cgctgtcatt
      961 tgttcatggc gataaaatct tttctattat taacaatcat aaagatgcca ttagcctgct
     1021 gattttttcc gtggttggcg cgctaactgt acagctcact tttttgctaa ccatcgaaaa
     1081 atcgaacgca gccacggcaa cggtgctgca attcctctca ccgacgatta tcgtcgcctg
     1141 gttctcactg gtgcgtaaat cgcgcccggg cattctggtt ttctgcgcta ttttgacatc
     1201 gctggtcggg acttttttat tggtgacaca cggtaatccg acgtcattat cgatctctcc
     1261 tgccgcgttg ttctggggca ttgcctcggc atttgctgct gcattctata ccacctatcc
     1321 ctcaacgcta attgcccgct atggcacgtt accagtcgtc ggctggagta tgctgattgg
     1381 cggtctgatt ctgttgcctt tttatgccag acaaggaaca aactttgtcg ttaacggcag
     1441 tttgattctg gcgttttttt atttggtggt cattggtacg tccctgacat ttagtctgta
     1501 cctgaaagga gcacaattaa ttggcggtcc aaaagccagc attttgagct gtgcagaacc
     1561 attaagtagc gcgctactct ctttgctgtt gctggggatc acgttcacat taccggactg
     1621 gctgggaacg ctgctgattc tgtcatcggt gattttgatt tcaatggatt cccgtcgccg
     1681 cgccagaaaa ataaatcgtc cggcgcggca taagtgagaa ttaccagcca ggcaccgcgc
     1741 caccgttaaa aatggtttct gccgctttag cgacttcggg tgattgataa gattgcagaa
     1801 attccttcac gttttctgca ttcttattat cttcccgtgc caccaaaata ttcacatacg
     1861 gcgaattctt atcttcaata aatacgctgt cgtgcaccgg agaaagcccg gtctgctgaa
     1921 tgtaagtggt gctgataatc gctacatcaa ctttgggatc atccagtacg cgcgggagct
     1981 gcgccccctc gagttccata atctgcaaat gacgaggatt atcggttata tccagcgcgg
     2041 taggtaataa cccttttccc tctttcagag taattagctt ctctttttgc aacagtaaaa
     2101 gtgcgcgacc aaggttggtc gggtcgttgg ggatcgccac tgtcgcgcct tcttttattt
     2161 gcgccacggt tttgattttt ttggaataac ccgccatagg gaagacaaac gtatttccca
     2221 ccgctaccag tttataacca tgcgcctgat tatcttgttc aagaaagggt cgatgctgga
     2281 agacattcgc atcaagttcg ccatgatttg tcgcatcgtt cggtagcaac gaaccgctaa
     2341 atcctaccag ttcaacatcg aggccatatt tctcttttgc caccttttta gcgacttccg
     2401 cgacatcttg ttctgcgcca tttataacgc caactttaat gtgttttgca tcgctgctac
     2461 tctggtcgca acctgccagc agaattccgg ccagcaataa tgcggcccct gtccgtagat
     2521 gatgtgttgt cagtttcatt tttttatcct tttattaatg attacctgac tatagcggta
     2581 aggtcgctgc ggtttaaaaa acgaaacgct atcgataaga ataaaaagga ataaaagtgg
     2641 aatataaagt ctggcacttc ttactgacca cgcaagcgcg tttcgtacag catgatgaga
     2701 gcgatgaaag caaactacac ttatgcttca ttcgatacac atttgtaaaa ggttgaatcc
     2761 atgaaaccaa cgacactact gcttattttc acttttttcg ctatgccagg catcgtatac
     2821 gccgagtcgc cttttagctc actgcagtcc gcaaaagaga aaaccacggt attacaagat
     2881 ttacgtaaaa tttgcacgcc acaggcgtca ttatcagatg aagcgtggga aaagttaatg
     2941 ttgtcagatg aaaacaataa acaacatata cgcgaggcca tcgtggcgat ggaacgtaat
     3001 aatcagagca attattggga agcgttgggt aaggtagaat gcccggatat gtaagaacag
     3061 caacaactac tgaccaacgc ttctttacct gatatcagga tttcttcatt ttcacctttg
     3121 cagtaaccaa caatgcagtc agcaacatca atgtgccgga caacatcaac ggcgaagtca
     3181 gaccaatatt atccagcgca taaccgccga ttgccgcgcc acaggtatta gcaagctgaa
     3241 taaccgccac ctgaatagac ccggcttttt ctgcctgatc ggccagcgag cgggtgatcc
     3301 acgttgacca gccgacggga accaatgcaa aagttagccc ccagataatc gccacgccgg
     3361 tagcaacgat tttatcgctt ccccacaacg tcagtaccaa cgcactcaca gccagtatta
     3421 acggcgcgcc tgctaaggcc agttttaccg aacgtttaag aatgaacgac gaaagcgacg
     3481 taccaataaa gctggcgata ccaaaactca acagcaccag cgttaagcca tccacgccga
     3541 atcccgccag gttcatatac accgggcgaa tatacgtgaa gaaagcaaac tgcccggcga
     3601 aagacatgaa gatggcgatc atccctgcca tcacacccgg acgttgtaat aagcggaaag
     3661 tattttgttt ctgatgcgag ggttcgcctg gcagtgaagg caatgatttg ataatccaga
     3721 aaatacacag cacgcccatc accgccgccg cattaaagac attgcgccaa ccgataagct
     3781 cgcctaaaaa actgcccaac ggcgcggcaa tcaccagcgc aatagaaacc gcgccgaaga
     3841 tcaccgacag cgccttcggc accgtacgcg gcggcaccag acgcatggtc agcgacgccg
     3901 acatcgccca gaacccgccc agcgccagcc ccagacaggc acgaccgatt aaaagcaaac
     3961 tgaatgagtt agcaaaggaa accagcaagc aggagagcgt cagcaaaacg gcaaacaaaa
     4021 taacaacgta gcggcggtca gtagcctgaa ttgtctgggt aataaacaaa ctggcaaaca
     4081 ttgccacaaa ggcggtcacg gtcaccgatt gcccggcaac cccttccgaa atgcctaaat
     4141 cctgggccat tggcgtcaac aaactgacgg gcaaaaactc aacgataatc agacaggcga
     4201 cacaaaacgc caccgagaaa acggctgacc agttcggtcg ggtgatggca tccgcgccgc
     4261 ggttttcggc aataaattca ctcatggtgt tacccgtggc atgtttcagg ggaaaagccg
     4321 accactttaa cattgaaatg tgtgacgcat ttaacgtttt tgcaactttt acggtgttgc
     4381 ttgagctgga gttaagatcg aaacggaaca gggcaaagat taccggatgc ggcgtgaacg
     4441 tcttatccac ccgacaggtc aggcgcggtc tgtaggctga taagacgaaa cggtttcaat
     4501 gcaaccagtg aacgccctcg gcaggctgaa agaacgcgtt atagcgcatc tgaaaagcat
     4561 taatatcctg catttcaggt tcggtttcgc gcagaaaacc tagcgccagc ctgacctgag
     4621 cgtcggtaat cggcgcggcg aggcgagctt tttgtaaaat ccgatgccat tgcagcaggt
     4681 tctgttcgct accatcgaca atgacaattt gccagatgag caacacctgc gcggcgtttt
     4741 gcaggtgcga ctcatccgga cgatgcaaat aacgtaaaaa ttcgtcacca gctgactttc
     4801 ccatttgatc gaccatcgac tccacgggta cgacatcgat gttcagccga tcgctgagac
     4861 ggcgaatcgc ttttctggcc ccggatgtca gcacccgaaa accaaccaca aacactaccg
     4921 ccagcgtggc gagcattatc cagatcatga gttctcctgc gtaatcagaa ctcatgatat
     4981 ctggaaaccc tcgccagtta ctaatccacc agaataatct tcagtgcaaa cagagctgcg
     5041 accaccacca cacacaggtt cagatcgcgc cagcgcccgg tgcatacttt catgatgcag
     5101 tacgacataa agccgagtgc aatcccttcg gtgatcgaga aagtaaaggg catcatcacc
     5161 gtggtaataa acgcaggcac cgattcggta aaatcatccc agttaacgcg cgccaggctc
     5221 gaagtcatca gcacgccaac aaagattaac gctccggcgg ttgcgtaagg aggaactatc
     5281 gccaccagcg gtgagaagaa cataaccaac aggaacataa cgccaaccac aaccgcagtc
     5341 agccccgtgc ggccaccgac tgccacacca gaagtacttt caatataggc agtaacagac
     5401 gaggtgccga taaacgcacc cgccaccgaa ctgacgctat caacatacag cgccttattc
     5461 atattgggga atttaccgtt accatctatt aagcccgctt tatcagttac accaattaat
     5521 gttcctgatg aatcaaatag gttgatcagc ataaaggaga aaatgatacc ggcgagttca
     5581 agtgttaacg cgccgctcaa atctacttca ccaatgacgc cgctaatatc aggcggaatg
     5641 gaatagacgc cgctaaaatg aacatcaccg aaaaataatc cacagcaaga cgtcaccaca
     5701 atagaaacca gcaccgcggc atgaaaatga cgtgatgaca acacggttat aataaaaaac
     5761 cctaaaatac ctaacaacac gccgtgagaa cttaaatcgc caatcatcac cagcgtgtct
     5821 ttattggcga caataacgcc agtatttttt aatcccatta aggcgataaa taatccaatt
     5881 ccgctggtga taccaatacg taaacttaag ggaatgttgg agatcatcca gtaccggata
     5941 cgaaacagcg tgagcaaaaa tagtccaact gcgccccaga atattgcgcc catcccggtc
     6001 tgccaggaga tgcccatcgc ccccacgacc acgaaggcaa agaaggcgtt cagccccatt
     6061 gccggagcca gcgccacggg taagttagca aatatcccca tcgcaatact gccgataccg
     6121 gcaatcaaac aggtggtaac aaacaccact ttcgggtcca tttgtgccgc gccgaggatt
     6181 tgcgggttca caaaaacgat gtacaccatg gttaaaaaag tggtcatccc cgcaatcaat
     6241 tctgtgcgga cggtggtccc atgctgaggt agtttaaata atcgcgaaag cgtccctgat
     6301 tcattactca cgtaatcggt attgtcatta ttcatttttt tgtccattgg aggagattta
     6361 atcccttgct tttgtaaaac aaatgacaac aacggttcag tgataattat cacatttcaa
     6421 ttgcacatta atggatattc tttaataatc tcgcgacgtt tctttatgat aaataataat
     6481 caaattgata aaatcaaaat gagaaaaata tgaataattc tattaaccat aaatttcatc
     6541 acattagccg ggctgaatac caggaattgt tagccgtttc ccgtggcgac gctgttgccg
     6601 attatattat tgataatgtc tctattctcg acctgatcaa tggcggagaa atttccggcc
     6661 caattgtgat taaaggacgt tacattgccg gtgttggcgc agaatacact gatgctccgg
     6721 ctttgcagcg gattgatgct cgcggcgcaa cggcggtgcc agggtttatt gatgctcacc
     6781 tgcatattga atccagcatg atgacgccgg tcacttttga aaccgctacc ctgccgcgcg
     6841 gcctgacgac cgttatttgc gaccctcatg aaatcgtcaa cgtgatgggc gaagccggat
     6901 tcgcctggtt tgcccgctgt gccgaacagg caaggcaaaa ccagtactta caggtcagct
     6961 cttgcgtacc cgccctggaa ggctgcgatg ttaacggtgc cagttttacc cttgaacaga
     7021 tgctcgcctg gcgggaccat ccgcaggtta ccggccttgc agaaatgatg gactaccctg
     7081 gcgtaattag cgggcagaat gcgctgctcg ataaactgga tgcatttcgc cacctgacgc
     7141 tggacggtca ctgcccgggt ttgggtggta aagaacttaa cgcctatatt actgcgggta
     7201 ttgaaaactg ccacgaaagt tatcagctgg aagaaggacg ccggaaatta caactcggca
     7261 tgtcgttgat gatccgcgaa gggtccgctg cccgcaatct caacgcgctg gcaccgttga
     7321 tcaacgaatt taacagcccg caatgcatgc tctgtaccga tgaccgtaac ccgtgggaga
     7381 tcgcccatga aggacacatc gatgccttaa ttcgccgcct gatcgaacaa cacaatgtgc
     7441 cgctgcatgt ggcatatcgc gtcgccagct ggtcgacggc gcgccacttt ggtctgaatc
     7501 acctcggctt actggcaccc ggcaagcagg ccgatatcgt cctgttgagc gatgcgcgta
     7561 aggtcacggt gcagcaggta ctggtgaaag gcgagccgat tgatgcgcaa accttacagg
     7621 cggaagagtc ggcgagactg gcacaatccg ctccgccata tggcaacacc attgcccgcc
     7681 agccagtttc cgccagcgac tttgccctgc aatttacgcc cggaaaacgc tatcgggtca
     7741 ttgacgtcat ccataacgaa ttgattacgc actcccactc cagcgtctac agcgaaaatg
     7801 gttttgatcg cgatgatgtg agctttattg ccgtacttga gcgttacggg caacggctgg
     7861 ctccggcttg tggtttgctt ggcggctttg gactgaatga aggtgcgctg gctgcgacgg
     7921 tcagccatga cagccataat attgtggtga tcggtcgcag tgccgaagag atggcgctgg
     7981 cggtcaatca ggtgattcag gatggcggcg ggctgtgcgt ggtacgtaac ggccaggtac
     8041 aaagtcatct gccgttaccc attgccgggc tgatgagcac cgacacggcg cagtcgctgg
     8101 cggaacaaat tgacgccttg aaagccgccg cccgtgaatg cggtccgtta cccgatgagc
     8161 cgtttattca gatggcgttt ctttctctgc cagtgatccc cgcgctaaaa ctaaccagtc
     8221 aggggctatt tgatggcgag aagtttgcct tcactacgct ggaagtcacg gaataataaa
     8281 aaaagcccgg cgtcatgccg ggcaaaagtc accagttacg tttatgccac tgtcaactgc
     8341 tgaatttttt tctcgcggcg gattttgcgt tcttccatta ccgccactat cgccatcagg
     8401 cagatacaac caatcgcggc gatatccagc gcggcgaagg tgcctgccca gccggtaagg
     8461 ccgaataccg gcgtcccatc ggcaatcatt cccagaccta acttggcaaa gctgtcacca
     8521 atcaggtaag caaaggtgcc tttaatacca tcggcagcgc caatcgcttt tttaggtaca
     8581 aagccaacag cagccacacc aatcaacaat tgcgggccaa agaccaggaa acccaacgca
     8641 aagagagaag ccagatagat atattcgtta ctggcatgtt gatacacacc gagcgtggcg
     8701 ataatcagcg ccagcgcgat gcaggccacc aggccacggc gaccgttcgc caggtcagag
     8761 agccagcccc acagcagcgt accgaccagc gcaccagctt caaacagcgt aaagccctga
     8821 atcgccaccg ctttagagag tttcagttcc tggaacgcgt atacggttga ccactggtcg
     8881 ataccaatac gtaccacata gaggaaaatg ttggcgaagc acagcagcca gatcactttg
     8941 tttttcagca catactcaac aaagatctgc cacttggtca tatcggtaga ttctgtctct
     9001 ttgtcctctt cgctgatctc ctcgccgaac agttcttcag ctttgccgag gccataagat
     9061 tccggggagt cgctgccgta acgcaggccg ataaaaccga caatcagcgc gataatcgac
     9121 gggaagataa acatgccgat gacatggcca tcgaacaggt aatttgcccc gaacagcgcc
     9181 acacctgctg cgcctgcacc gccaaggttg tgagaaatat tccagaaacc gaggaatgtc
     9241 ccgcgtttac gacgcggcgt ccatttggtg atggtggagt aactgcacga accgccggta
     9301 ctctggaaaa agccgcttaa ggcgtagaag gcaatcatca ggaacaggct aaccgagccg
     9361 ctgcccatac tggcactgaa gcccagcata caaatagcag agaggatcag catgaacggc
     9421 aggaattgtt tggtgttttt gccgtcggcg tagtaggaaa ccagcgtttt acccacgcca
     9481 taagtgatgg agaaacccag gccgatcatc cccagctgcg tcatgctcaa cccgtaggtc
     9541 gaaatcatat cgttctgcgc gatgttaaag ttcttgcgaa tcaggtacat cgtcaggtag
     9601 ccgataaaga ccaccaggta ggattgcatg aacggtttga accacatttt gcgccgcact
     9661 tcgagcggaa ggtccagggt cggcttgcga acctggttta agaaagccag catgggttac
     9721 tcctgaaatg aatacctgcg tgaggcatgc attgtaaaaa tcagcagcaa atcaggcctg
     9781 agatagcgtc caggcaaaac ctggaaaatt tcttagtttt gccggatatg aagtgaaaag
     9841 gtgagatgca tcacgcttcg cgcggtgtct gggcgttcaa aaagggcagt aacagcagtg
     9901 cggaaatccc ggcggcgata gagataacca caaaaaatcc gctccagtgc caggtatcga
     9961 gtactttcgc cagcggccaa ccagcaagcg acgcccccag ataagcaaac aagccgacaa
    10021 accccgtcgc cgcccctgcc gcctctttgt gggaacactc tgccgccgcc ataccgatta
    10081 acatctgtgg gccaaagaca aaaaaaccaa tggtgaagaa gcaggttgcc tgcatcacgt
    10141 agctggcaaa tggcatcagc cacagggagc cgactgaaag caaaattccg gcggcgaaaa
    10201 tcaaattcat cggccctcgg ttgccgttaa acaatttgtc cgagccccaa ccggctacca
    10261 gcgcaccgat aaatccgccc agttcaaaca tcgtcactgc cgtattcgcc gtgaccagat
    10321 cgacgcccag tgtctcggac atatacaaat tgccccagtc gttgatcgcc gcccggacca
    10381 catagaccag cacatagcaa aacgaaagca gccagatata cggattcagc aacacatatt
    10441 tggtgaggat ctctttacgc gtcaaccctg ccccttcttg ttgttgagca atttccagcg
    10501 cgtcgtgtcg ccattcaccg accgccggta aacctaacgc ctgcgggcga tcgcgtagcc
    10561 gccagcagag aaaaatcccc acgactatcg ccatacaacc agcaatcatc atcccggcac
    10621 gccagccgta atgcagcgca gccgctgcca tcacaatggg aatgagtgcg ccgccgacgt
    10681 tatgcgccgt gttccataat gcccaccaac cgccgcgctc ggtacgtgaa taccaggccg
    10741 ttaacagacg cgcacacacc ggtgaacccc agccctggaa aaaggcgttc agcacccaga
    10801 gcacggcaaa cgcccatagc gacgtcgaga agccaaacag aatgttgata atgcccgtgg
    10861 cgataagccc tatccccata aaataacggg catttgagcg atcgctgaca atgccggaga
    10921 caaacttcga cacgccatag gtaatgtaaa acagggtcgc taacaggccg atatcgctac
    10981 ggctgagcac gccgttagca aggatttctg gtacggcggc gttaaaactt ttccgcgtga
    11041 agtaaaacag cgcgtaaccc agccagatgg tcagcagaat atgccgacgc cagtagcgat
    11101 agcgggcatc aatttcatat ttatcagtca ttaatggcgc atcggcaggc gctttcagaa
    11161 acggcaacat catcaaacct tagacatagc gttgaggtag agaaacgctg acacgcgtgc
    11221 cgtgcagaca ggaaatgtgt aatgtgccac ccagcgccgt tacgcgctcg cgcattccgg
    11281 tgaggccaaa accttgttgc ccggaacccg gcggcaaacc gctgccatcg tcttcaataa
    11341 ccagcatcaa ccgttcatcc tgctgccagc cttgcagggt gaccgcgctg gcatcagcat
    11401 gtttcacaat gttgttcagc ccttcctggc agacacgaaa cagcgtcacg cgctggtttt
    11461 cgcttaacgc tgattcatcg attcgccatt cgagatggct gacaataccg cgcccttcca
    11521 gctccatttc ccgcatcagt gagcggatgg cctgctccag ggtgagatca tccaactggc
    11581 gcggacgtaa ccgacccaac aaacggcgca ccgcgtcgta aacgcccagc gatagttgtt
    11641 cgatgagctg cccgctctgc ttcacgctgg cgttatctgc cgccagccgc tgaacaatgc
    11701 ccgcctgagt acgaatagca gtgatggtct gaccgatatc atcatgcagc tcacgcgcca
    11761 catcacggcg cacgctctct tcggtttcca gcaaccgttc agccagatgc tgattgcgcg
    11821 ccagttcctt ttgcagcgac tggttaagtt cacgcaaccg ctggatgcca gcgccaagca
    11881 acaaccctgt cagactttgc accagcagcg agagcaataa atccaccgga tgatcgcgcc
    11941 aggtttgact ggcgatcagc gcgatggcgt tcatcaacgt cgcaatcagc gccccttgcc
    12001 aaccatagtg ccaggccagc gcgataatcg gcagcgccag acagaatggc gtaaagcgcg
    12061 acagttcgtc cggcaatccc aactggagcc agagactgat aacaaacagc agcaagtacc
    12121 agaccagatg tcgcccgcgc cagttgattg gctgagaaac cagtgacgga ccgagcggca
    12181 gccaggtgtt attggcgaga tagtgccaga acaccagaca tatcggggcc agcgtcaggc
    12241 cgccagttaa agtcagcaac agcgcattcc acgactcttt gccgtgccaa agccagggca
    12301 gcgactgcaa caacgccgcc gccgttaacg ccgccccctg taacagcaag gtgcgccagt
    12361 cacgctgatg gcgatagcgc gagatcagcg ctacgggcag taacgtcagt aaactaccga
    12421 tcatcaataa cggaaaatgg gttaaaccga ccgcctgcgt tagccagtaa atcagcagcc
    12481 actccgcgcc cagcaatacg ggccagtatc cgcgcgggca ttgcagcatt agccccagac
    12541 gcagaccaaa cggaaataac agcaccgcca tatcagggcg ctcaaccaga tgcaggctga
    12601 tactccacag gcaaaaccat gcggcagaga agataaaaaa gcaggcaata acggtaatta
    12661 agcgggagaa caacgtcttc atcaccagcc atcaaacatg cggcgcgcca gctctacgtc
    12721 gttactgacg cccagttttt ccatcagatt ggcgcgatgg acgtgtaccg ttttcggtga
    12781 caagcccagt tcggcggcaa tctctttcac cgccattcct tgcgccagtt tttccgccac
    12841 ctggcgttca cgtttggtta gcgggtcctg acgaccggat gccagtttaa tggcaatatc
    12901 cggcgtcaga taacagccgc ccgtggcaac cgtatgcacc gcagcaatga gttcatccgg
    12961 gctacagcgt ttggaaagaa agccgcgtgc ccccgcgtta agcgcctgct caaccagcgc
    13021 aggactgtcg tgaacggaga gcataatcgt cgccatacct ttcggcagct ggcttagcag
    13081 ctccagaccg gagatatcgg gcatggagat atcgcaaata cacacctgca caccgcgccc
    13141 cggcagcccc gccagcgcct cgcgccccga accaaactcg gcaactacct gcaaatcagg
    13201 ttccagcccc agcagctgcg caaagccgga gcggacgatg aggtgatcgt ctataagggc
    13261 aacggtgatc atggtcttgt cctggcgggt aaaaaaaata cgcgcttacc ttaacgataa
    13321 gcgcgatgtt gttcaagcct tgagcggtta ctgaaaaaac accgcgatct tgttaaacat
    13381 cgtcggatcg gactgattac gctgcacttt cacgacatct tccagcttat cgatttggct
    13441 tatcatctgc tccagacgct ggtcgtcatt gaccagtagc cagatatggc ttttgtcgct
    13501 gtcctgaatc ggcagacaaa gaatgccttc aacgttaaaa gcgcggcggg caaaaaggcc
    13561 acaaacgtgg gtcattacgc ccggatggtt gcgaacggtg agctccagaa ttacgttgtc
    13621 atgagttgtg ttttgcatgg cttattcccc caccatttca gtattcgccg cacctggcgg
    13681 caccatcggg taaacttttt cttcggcatc aatgcgcaca tggatcagcg ccgggccagg
    13741 gcgattgatg atttcctgca atgaagcctg cggatcggct tcgttattca aatcacaggt
    13801 ttcgaggccg aatccggcgg caatctgcat aaagttgatt ttgcccggat aggtggcggc
    13861 aaaaacgcct tgctcgtaga acagactctg ttgctgatgc accagcccca gcgcttcgtt
    13921 gttcatcaga atgattttga catccagctg attttcactg gcggtcgcca tctcctgaat
    13981 attcatcatc aggctgccgt cgccggagaa acacaacact ttgcgatccg ggttcgccag
    14041 cgcagcgcca atcgccgcag gcaggccaaa acccatcgtg cccagcccac cggaggtcag
    14101 ccactggcgt gggcgattga gcggataagc ttgcgcggtc cacatctgat gctgaccaac
    14161 gtcggtggtg ataattgcat tgtcatcgac acaggcggca acggcgttga tcaggccgta
    14221 atggcttaac ggatcgcacg ctttcgggat tggacacgga aactcacgct gcaaatccgc
    14281 taccaactgg tgccactctg cacgcggttg cgcttccacc agcgggatca actgcgccag
    14341 cacgtcatca acatccgcct gaatcgccac gtgcggctgc ttgattttac ccagctctgc
    14401 acggtcgata tcgacatgaa tgattttggc attcggacag aactgctcgg ttttgccaat
    14461 cgcccggtca tcaaaacgcg caccgagcac tatcaacaaa tccgcctcct gcaaaatata
    14521 gttggtgctg cgcacgccgt gcatccccag catacccagc gacaacggat gcgcttttgg
    14581 caacatgccc agcgccatta aagtcatggt ggtaggcagt tgcgctttct ccgccagttc
    14641 acgcacccgt gcgggcgcat tgatcacacc gccgcccaga taaagcaccg ggcgtttggc
    14701 agcgttaatc atcgccgctg cgtcacgaat gctttcttcg ctaaaggcgg gggcggcggc
    14761 tttttctgcc atagcgggct gtgtttcaat ctcaaaaact gccgtttgca catccttagg
    14821 aatgtctatc cacaccgggc ctgggcggcc tgattgcgca atgcggaagg catcgctcat
    14881 gacctgcggg agttcttcga tatgtctgac cagatagttg tgtttggtga tggggataga
    14941 gatgccgtag gtgtccactt cctggaaggc gtcggtgccg atcatcgagg cgggaacctg
    15001 accagtgatg caaatcagcg ggatggagtc cagccgcgca tcggcaatgg cggtcaccag
    15061 gttagtcgca cccggtccgc tacaggccat acagaccgcc ggtttaccgt cggtgcgcgc
    15121 cattccctga gcgataaagc ccgcgccctg ttcatgacgg gccagaatat ggcggatttg
    15181 cgtgctttgg cttaaggcat cgtaaacagg caggatagaa ccgcccggaa tgcctgtcac
    15241 aatcttaatg ccctgctgtt ccaggaaatg aacgataaat tctgcgccgg taaagcgctt
    15301 acgcgtcgat gttgtgcccg aacttgccat gctccagtcc ttttcttctg ggccgacttt
    15361 ccgggaggtg cttaaacgaa aaaccccgcc cggtttgcgc cggcggggtt ttggaatcgt
    15421 gtgttgttcc agtccctacg gcgcattgcc gacgaccacc accacacgca cgacgaccac
    15481 tgcggcggat ggcgcagttg gtagtagttt tgcgttgagc atggaagtag tcattgggga
    15541 ccttgttggt tttgtgttta acaatattta tacaagcaca gctttacagg ggagacaatg
    15601 gaaaattttt cagcaaggga aaattgaggg gttgatcacg ttttgtactg aattgcagat
    15661 aacaaaaaac cccgccggag cgaggtttcg tcagtcgcct gcggctggta accgcaaagc
    15721 acactgtatt atgtcaacac tgaaagtata cgtgttccgc gcagaacgcg caatttcggc
    15781 acgaattttg acgtatttag tgcatagttg agtatcgatc acagtttgcg ttttgtccaa
    15841 atattactgt ttatttatac agtaaacttc tataatatca ctgtacgcaa tgtgttatgc
    15901 gggggccgca tcgttacccg gcgcactaag tcctggctga aacgggtggt gccgtcagcg
    15961 ccttaacccc gcgtgagcac actgtgttat gtcaacaagc acaacgtttc tccttgagat
    16021 accgcgtgca caacagctgg caacaggcag cggaaaggta cgtcagctgg cagtgctcct
    16081 gaaccacagg agacgcgtat gaacctggtg gatatcgcca ttcttatcct caaactcatt
    16141 gttgcagcac tgcaactgct tgatgctgtt ctgaaatacc tgaagtaatt cagattcaag
    16201 tcgcaccaaa ggggagcggg aaaccgctcc ccttttatat ttagcgtgcg ggttggtgtc
    16261 ggatgcgatg ctgacgcatc ttatccgccc taccatctct cccggcaaca tttattgccg
    16321 cttttgttta catattctgc cgctaaacaa ttccccattc ctggcgtata tctggctaac
    16381 attcatcaat gtgatagatt cctctcccgc atttatggga atgcgtagtg acttattcta
    16441 attattttta taaaagcatc cgtgataatg aaaaggcaaa gaaacgtcaa tttgttattg
    16501 atgttggtat tactcgtggc cgtcggtcag atggcgcaaa ccatttatat tccagctatt
    16561 gccgatatgg cgcgcgatct caacgtccgt gaaggggcgg tgcagagcgt aatgggcgct
    16621 tatctgctga cttacggtgt ctcacagctg ttttatggcc cgatttccga ccgcgtgggc
    16681 cgccgaccgg tgatcctcgt cggaatgtcc atttttatgc tggcaacgct ggtcgcggtc
    16741 acgacctcca gtttgacggt gttgattgcc gccagcgcga tgcaggggat gggcaccggc
    16801 gttggcggcg taatggcgcg tactttaccg cgagatttat atgaacggac acagttgcgc
    16861 catgctaaca gcctgttaaa catggggatt ctcgtcagtc cgttgctcgc accgctaatc
    16921 ggcggtctgc tggatacgat gtggaactgg cgcgcctgtt atctcttttt gttggttctt
    16981 tgtgctggtg tgaccttcag tatggcccgc tggatgccgg aaacgcgtcc ggtcgatgca
    17041 ccgcgcacgc gcctgcttac cagttataaa acgcttttcg gtaacagcgg ttttaactgt
    17101 tatttgctga tgctgattgg cggtctggcc gggattgccg cctttgaagc ctgctccggc
    17161 gtgctgatgg gcgcggtgtt agggctgagc agtatgacgg tcagtatttt gtttattctg
    17221 ccgattccgg cagcgttttt tggcgcatgg tttgccggac gtcccaataa acgcttctcc
    17281 acgttaatgt ggcagtcggt tatctgctgc ctgctggctg gcttgctgat gtggatcccc
    17341 gactggtttg gcgtgatgaa tgtctggacg ctgctcgttc ccgccgcgct gttctttttc
    17401 ggtgccggga tgctgtttcc gctggcgacc agcggcgcga tggagccgtt ccccttcctg
    17461 gcgggcacgg ctggcgcgct ggtcggcggt ctgcaaaaca ttggttccgg cgtgctggcg
    17521 tcgctctctg cgatgttgcc gcaaaccggt cagggcagcc tggggttgtt gatgacctta
    17581 atgggattgt tgatcgtgct gtgctggctg ccgctggcga cgcggatgtc gcatcagggg
    17641 cagcccgttt aagcgcacgt caccgcagca tcgtcatcag ctccatggga gaacgatgct
    17701 gctttatcag atcacgcatc acccgcatat gcggtgcgga gtaagaataa aacgcctgat
    17761 agcccgcaca aagcacgctg tctggcgtct cctgccgagc gtgcgggcac aggcgatgcc
    17821 agtcgcacgc ctggcagtca cagcgcggtt gcgggttttc gctgccacac catttttgta
    17881 aggtggcgtc aaaaagctca atcgagatac gactgatatc tgcccgcacc caacactcga
    17941 acagggcaat taaaaatttc ccccacagct ctgctgtcac cgaagcggcc gtcagatcgc
    18001 cccggtcatc aaattcaaga tagggaatga gctgtacgga gcggatgccc cgctgtttga
    18061 aattgtgata aaaatcggca ggttgcagag catccttgta ctctacaacc agtttatgcc
    18121 tgtcctcttc agcatcaatg acctgacttc ctgtcatgcg actctctcaa taaatacgat
    18181 aagttgatgt atatgcgtta cagcaaacag tattgcgaga gataacaccg cgagggagat
    18241 caaaaatttg tcacggacta cgtgaaattg ggaaaaatcg ctattcgtga catccattaa
    18301 attgcgatta cgggtgtagt gccagaggat cagcgccacg atggcgagaa tgccaatcga
    18361 aatccagaat aacatgcccg cctggtgcca gttgtgtttg atagccaacg ccatcaacgc
    18421 gccgtagccc agcatggtac gaaaccacgc cagtgatgtg cgctccggct gcagtcctgg
    18481 gtcggcaatg cgtctggctt tgcggctatc cggcatacaa caccagtccc ataacgatca
    18541 ccgccacgac catcaatatt aagctaatga ttaataagct gttggtgtag ggcaggtcct
    18601 ctttcagacg catcgctttt tcattgcgta accagcgcaa gtagccatac atcgctaacc
    18661 cgccggaaaa cagacacaac aacaacgcca gcagttcgcg aatgacgggc gtggcgaaat
    18721 ctggcgcaag ttgatcaagc ccaacccccg ccgccagaaa tcctagtgca gtacggatcc
    18781 acgccagaaa agtacgctca ttagccagcg agaagcggta atcaggcgct tctccgaggc
    18841 gggaaatttt cattgttgct cctttgcaat ttcactaacg ctctaccttt agcggttttt
    18901 ttaagaattt cgtccgcccg tttcctgata tgcttttgcc atccgctaca aggaggtcag
    18961 atgggtatca tagctcaaaa taaaatcagt tcattgggca tgctgttcgg tgccatcgct
    19021 ttaatgatgg ggattatcca cttttcattc ggccctttct ccgcaccacc gccaacgttt
    19081 gaaagcatcg tggcggacaa aacggctgaa attaaaagag gtcttctcgc cggaataaaa
    19141 ggcgaaaaaa ttaccaccgt ggagaaaaaa gaggacgtag atgtcgataa aatcctcaat
    19201 caaagcggta tcgcactggc cattgctgcg ctactttgcg catttattgg cggtatgcgt
    19261 aaggaaaatc gctggggcat tcgcggcgcg ctggtttttg gcggcgggac gctggctttc
    19321 cataccttgc tttttggtat cggcatcgtg tgcagcattt tgctgatatt ccttatcttt
    19381 tccttcctga ccggcggttc actggtttaa gcagcctgaa taatgcccgc cgggtgatca
    19441 tcagcgggca ttatcgtcag aacttctgtt ttttctcctc caccttcacc ccttgtgtcg
    19501 gtaggccggt gtcatagtcg cgtacaactg gcgaatagcc atcttgtgga cgtggacgaa
    19561 acgcccccat ccagcgcggc cgtgcatctt tacgccacgg acgcagactc cattggtaac
    19621 tgcggaacgg atcgcgaatt ttgtccatgt aatccaataa ggcgtcatgc attttgctgc
    19681 gaacgtctgc aaaacggata tcatcgatca ggttatgcat ttcatttggg tcattacggc
    19741 gatcgtaaag ttcatcactg gtgaagaggt tgagtaccag tttaaagtca tccgtcaccc
    19801 agcaacgcac cggaataaaa ccgccaaagc tgtcatgctc aatctcgtag cggttaaatt
    19861 ccaccatcac gccgcgtggc tctttcacgg caaggatatt ttcccccggc agaatctctg
    19921 gtttttcaat atctgccagc gccatcattg tcggcagtaa atcgatatga ctgactggcg
    19981 tatcgacctg tcgccgctcc ccttgcggcg aacggatgat cagcggaatg cgggtgatgt
    20041 cgtcatacat cgccgcccct ttactgatca gcttatgtgc gcccatcatt tcgccgtgat
    20101 cggaggtata aataacccac gtattttcac gttgctctgg cgttaaggca ttgatgaccc
    20161 gtccgatttg gtcatcaaca aagtcattac aggcaaaata gagcggatgg tgataaagcc
    20221 cgtcatcacc gactggcgat ggcatcgcct gcgcccataa gcggtgatgt tccggtttgt
    20281 tagccaggtc atcctgtgct ttctcgccca gctcgtagta aaaatcagcg tatttctcta
    20341 aatactccac cggacaggtg aacgggtgat gcggctcatc atacgaaacc accatcagga
    20401 aaggctcgtc tgcgcgcgca ggctgttgca gaaaatccac cgcccgattg ctgatacgat
    20461 gcgcccaggt gaaggtttcg tcgatatggt tcgcctgtaa atcttcgacg ctgtttaggc
    20521 cattgcgcca caggctaatc tctttttccg tcagttcgct aagatagttc gccccatcga
    20581 accagtaatc agcgtcccac tccggcggac actcgccagt gccgaaatag tcatgaccgt
    20641 cgagatgcca tttgccgatg taacaggtgt gatagccggc atccttaaag tagcgcccca
    20701 tagtggagat gtttttgcct ggcgcgacgt tgttggtcca cgggccggac tggttagcgt
    20761 agataccggt aaatagtccg gcccgtgcag gcgtacaaac cggtgaacag gtgtaggcgg
    20821 aattaaagcg aataccttcc gccgccagac tatcaatatt ttgcgtattc agcggtttac
    20881 cgctatagca accgaccata ttggtggcct gggtatcggt catgacgaac agaaaattgg
    20941 ggcgtttcat aggctatcct tcccgtcggg agtaaaggtt acggctgggt cgtgacgatg
    21001 ccgccagctg tcaaaaatca ggtagacaat cactacggcg gcaatgaaat aactgatcat
    21061 cgctaaccag cgcgtaccgt agccgccgaa ttcagccagc ccggcataga cgccaatcat
    21121 cgcgaacagg atgccaattg acgcgatctt gacgtttttc cacggtttca tgtccaccgc
    21181 aaacgcatct ttgaaggtga acggcgtggc gcgcggtttg ataaaaccga tcaccagcat
    21241 cacgaccacg ttgatgcaga acgtacaggc cagcacatag aggaaatgga agtcgaactt
    21301 caccagatag ttgatggtga tgtagctgat tatgccaatc cccatcgcta cttttgccgc
    21361 cagcgccggg atgcgcggga agaaaaagcc cataatgatg atggtaacca gcggcacgtt
    21421 gtaaatgccg ttgagctgtt tcatccagct atacagcccc tgcggcgcgt tggcgatcca
    21481 cggcgcgacc agcaccgaaa cgatagcgat aaagaaacca aatttgcgcc cgacggtgac
    21541 cagctgctgc ggctcggcat tctggttaat gatgcgacgg taaataccca tactgaataa
    21601 cgtactggcg ctattcagaa agccgttgaa ggtactgatc accgcaccaa ataacaccgc
    21661 gccgaagaaa cccaccattg gcactggcag aacgttattg accagcgtcg ggtaggccat
    21721 gtcggctttc ggtaaatcct gatacagatg aaacgcaatc aaccctggca gcaccagtac
    21781 cagcgggtcg agcattttca gcaccgccgt taacagcgcc cccttttgcc cttccgccag
    21841 gctttttgac gccagcgtgc gttgcacgat gccctgattt gtacaccagt aaaaggtgtt
    21901 caccagaatc aaaccggtaa atgccgcgcc aatcggcaag ggatcggtcg ggccaccgat
    21961 tgagtttaat ttctcggcgt gaacggtggt gagttgctca atgccctgca taaagctgcc
    22021 cttgcccatc gcgatcaggc caaataccgg caccatcaac ccgccgataa ccagcccaat
    22081 accgttgatg gagtccgcca ctgccattgc gcgcagtccg ccgatcaccg catacaaaat
    22141 tcccgccaga ccaagcaaaa ttaccagtag ccagatagcc gcaccgtgag aaatctgtag
    22201 cgattccccg acgtgaaaca ggctgttgag cgccaacgcg ccggagtaga gaacaatcgg
    22261 cagaaagcag acgccggtgg caattaggaa gcagaagtcg atgataatac gcgtcgtttt
    22321 atcataacgt tcctccagaa aatcggggat ggtggcaatg ccgcgcttca gatagcgcgg
    22381 taaaaagatt agcgcgagga agatcagcgt caccgctgaa gtcacttccc agcccatcac
    22441 cgacatgccg cttttgtagg cctgcccgga aaggccgacc agttgttccg tggaaaggtt
    22501 ggttagcatt aacgaagcgg caataaccgg cgcttttagt gaacgtccgg caagaaaata
    22561 gccttgttgc gatccggtat ctgttttgcg gaccttccac caggtgatca ccgccaccag
    22621 cagcgtaaaa ccgacaaaac tcaagatttg taacgaattc atctcatagc ccttatttat
    22681 gtttatgtcc cggacgcatg aatataggga gaggtaaaat gcgtcgggtc aggcagtcag
    22741 attcttaaaa tacaaacgtc gtatccctga acggattgtt ttctgttaag ttcaggttgt
    22801 gagcataatt cgccggaggg atattaaaat gaatggaaaa ttgcaaagtt cagatgtaaa
    22861 aaacgaaact ccgtacaata ttcccttatt gattaacgaa aatgtgatct ccagcggaat
    22921 ttctctgatc tcgctctggc atacctacgc cgacgagcat taccgggtga tctggccgcg
    22981 ggacaagaag aaaccgctta tcgccaactc atgggttgcg gtgtataccg tacaaggatg
    23041 tgggaaaatt cttttaaaga atggcgaaca aataacactg catggcaact gtattatatt
    23101 cttaaagcca atggatattc actcttatca ctgtgaaggt ttagtctggg aacagtactg
    23161 gatggaattt acccccacca gtatgatgga tattcccgtt ggtcagcaaa gcgttattta
    23221 taatggcgaa atttataatc aggaactcac cgaagttgct gagttaataa cttcaccaga
    23281 agcaataaaa aataatctgg cagtcgcttt tctgacgaaa attatttatc agtggatttg
    23341 tcttatgtac gcagatggta aaaaagatcc acaacggcgg caaattgaaa aattaattgc
    23401 cactttacat gccagtctgc aacaacgctg gagcgtagct gatatggctg ccacgatccc
    23461 ctgtagcgaa gcctggttgc gtcgtctgtt tttacgctat accggcaaga cgccgaaaga
    23521 atattacctc gatgcgcgtc tggatctggc gctatcgcta ttaaagcaac aaggaaactc
    23581 ggttggcgaa gtcgctgata cgctcaactt cttcgactcc tttcatttca gcaaagcctt
    23641 taaacataaa tttggttatg cgccgtcagc cgtgctaaag aatacggacc agcacccaac
    23701 ggatgccagt ccacacaatt aacgtaactc tggccagtac gctttgttgg cctccagcaa
    23761 ctcatccaga atagctttgg cgaccgaggc gctcggtacc gttttcgaca acgtaatcgc
    23821 ctgccacagg tgctgatatg aacgctgttc ccaggcgtcc acgaccagtt tttccaccgc
    23881 cacttgctga ctcattaacc ctttctgaaa ctgcgggata tcgccgacca ccagtggttc
    23941 aggccgtagt agcgcacgcg catctgtttg cgatcttgca gcccaacaat ttgcgccatc
    24001 cggctttcaa taccgattgg catgtcacag atgttgagga ttttcgcatt cgggcgcaga
    24061 cgacgcgtgg cttctgcgac aatggctgcc gggttggagt agttgagcat ccaggcattt
    24121 ggtgaatatt tttccatata atccaccagt tccaggacgc cgccaatgga acgcatgccg
    24181 tacgctattc cgccgggtcc gcaagtttcc tgaccaacaa cgccgtggcg cagcgggatt
    24241 ttttcatcca gttcgcgcat cgggtatttg ccgacgcgga tgtgcgccat gacaaaatca
    24301 acgtcgctga atgccacttc aggatcggtg gtgtaactaa acgcaatgtc cggcgctttt
    24361 tctttaagga tgactttaca ggcttcggca atcacttcct gccgcgcacc atcgttatca
    24421 taaaatttca gtgcacgaag cgggaaacgg tcctgattcg ccaggagcat caacacgatg
    24481 cctggcgtaa aggtgcttcc accgcctgcg acaaccactg agaatttggt cactatactg
    24541 cctccgtaat ggcaacattt tctgctgatt gatgagaatt aattaagcta tcgagctgtt
    24601 cacgcagctg agatacatgc agaccaatga tcacctgaat ggcatcgcca ctacggaaga
    24661 cgccgtgcgc tcccagcttt ttaaagactt cgtcatccag cgtttgtgac atgtcatgca
    24721 gtgcaatacg taaacgcgtc gcgcaattgt taatgctgga gatattgccg accccgccca
    24781 gggcttgcag gataccggca gcctgatcca gctctttttt tggctctgcc gcggtggttt
    24841 ggcctcgcga ggctttgtat tcggcttttg agtagagttt cacttccgca tcttcacgtc
    24901 ccggcgtgca catgttgaac tgcagaatca gtgtgcggaa aaccacgaag tacagcaggg
    24961 taaagcacaa cccaatggcg atttgggtca gcatcatatc cgcgtggttg ctgaacatcg
    25021 ggatccagtt ttgcggtaaa acctggtcaa tcagacctcc gcccatgttg cccaccacac
    25081 caaagagata cattacggtc gacattgagg ccgccagcac ggcgtgtacc gcaaacagca
    25141 acggtgaaat gaacaggaag gtaaattcca gcggttcggt aattcccacc agcatggcgg
    25201 ttaaggttgc gggaatcagc aagcccgcca cttttacccg attttccggt gcggcagtga
    25261 agtacatcgc taaagaaatg cccacggcac caaagatttt tgagttaccg tgcagggcaa
    25321 aaccgccttc cgggaacaac gatttcagcg gctcggcgct caaactgaac tcttgcagat
    25381 gctgcgccca gtacatctga atgccgcctt caacagctgc cggaccaaag ataaactgtc
    25441 cgtagatgaa gtggtgtaaa ccggttggga tcagaatacg ttcgaggaag gtgtaaaccc
    25501 agaccccaag tgcacccgcc gaacgcagga acgcttgcag agattcaatc cccatttgta
    25561 cttttggcca gccgagcaac gtcagccagg cacaggggat catcaccagg aaggcgataa
    25621 tcaccacata agacgtcccc tggaaaatgc cgagaaaaac cggcagtttt ttatcgaaca
    25681 gacggttatg cagcgccgtc acaatgccgg aaatgataat tgcgccgata atgctggtat
    25741 cgagggtttt aatcccggcc atcattgtca gaccgctacc tgccaccgcg tcctgagtga
    25801 aatcgacgcc gaagtagctt ccccaggtca ttcccatcgc gttgatgaaa tagttccagg
    25861 tcaggaaact caccatcacc gccagacaag cacgcccctg cgcttgctta gcaaggccaa
    25921 tgggtaaacc gacagcaaaa atcagcggca tattacggaa taccgtccaa ccgccctctt
    25981 caataatgtg tacgatttgc gcgaataaac tgttcggatc ggtcagtgat tccccgacaa
    26041 acatcgggtt ttgcagcaag atggcaagac ccaccacaat cccggcgaag ggaaacagca
    26101 gcactggcgt gaacatcgcg ccgccaaagc gttgaatttg actgagcatt tccacatcct
    26161 cttttctcaa ttctgtaagt aggaagcctg attggttatg cggcaggcct ggagcgagga
    26221 taggaagatg cgatcggcag aacatgacga cccaatggga ttcgtgatcg ctttcatgct
    26281 tttcgttggg cggtagagat ctacgttttc gcgaaaaagt agacctctgt gagcacaggt
    26341 acacagcatc gaacacatct ttaaaaaaaa gatgtttttt caatcgatta agcagaactt
    26401 gtgtgcgcat tacccgggct tgcaggcaaa aaagagatct agagatgatc tacaaaagca
    26461 ttgcggagcg gttaagaatt cgacttaact ccgcagattt cacgctaaac agccttcttc
    26521 ccggtgaaaa aaagctggcg gaagagtttg cggtatcgcg gatgaccatc cgtaaagcca
    26581 ttgacctgct ggtagcgtgg gggctggtgg tccgccgcca cggtagtggc acttacctgg
    26641 tgcgcaaaga tgtactgcat caaaccgcca gtctgaccgg gctggtggag gtgttaaaac
    26701 ggcagggaaa aacggtcacc agccaggtgc tgatttttga aatcatgcct gcgcctccgg
    26761 ccattgccag ccagttacgg attcaaatca acgagcagat ctacttctcc cgtcgcgttc
    26821 gttttgtgga agggaaaccg ctgatgctgg aagacagcta tatgccggta aaactgttcc
    26881 gtaatctttc gctgcaacat ctggaagggt cgaagtttga atatattgaa caagagtgcg
    26941 ggattttgat tggcggtaat tatgaaagcc tgacgccagt gctcgccgat agactgctgg
    27001 cgcggcaaat gaaggtagcg gaacacacgc cactgctgcg gatcacctcg ttgtcatata
    27061 gcgagagcgg ggagtttttg aattattcag tgatgttcag aaatgccagc gaataccagg
    27121 tggagtacca tttacggcga ctccacccgg aaaagagtta accgatactc cagaagagca
    27181 ccgccagtaa ttggggggtg ataatgcgca ggaacattac caacggatag acagtggcgt
    27241 aagagagcgc cgccgcaccg ctggttggat gaagattatt agcaaacgcc agcgccggag
    27301 gatcggtcat ggaacctgcc agcatcccgc acatggtcag gtaattcatt ttggctaaca
    27361 tccgcgccag aatgccaaca gtaatcagcg gaacggcggt gatcagggca ccataaccaa
    27421 tccagcttag cccttcgcca ttgaccaggg tattcacaaa atccccacca gatttcagac
    27481 caacgaccga gaggaacagc acgatcccca gctcccgcag cgcgaggttg gcgcttggcg
    27541 gcataaacca gtacagcttg ccgatactgc cgatacgccc gaggatcaac gccataatca
    27601 gcggtccgcc cgccagcccc agtttcaacg cggccgggaa tcctggcaca aagacgggaa
    27661 tagaacctaa caatacgcct agcccgatgc caataaacac tggcagcatc tgaacctgtt
    27721 gcagtttttg ctgcgcattc cccagcacat tggcaacggc atcaattgcg gacggacgcc
    27781 ccaccagatt gaggatatcg ccgaactgca ggctgatatc gccactggcg accagttcga
    27841 ccccggcacg gttcaggcgc gagataacaa cgtcatagcg ttctttaaag tgcaggtcgc
    27901 gaatacgttt tccgagcacg ttttcattgg tgaccaccac acgctcgacg cgcaaatcag
    27961 tgcctttcgt ggacagcgaa gtatcgacct cctgaccaat caccagttgc gcattatgta
    28021 aatccgctgg ctgacccacc agatgcagca aatcgcccag ttggataatg gtatctggcg
    28081 aaggaacttt tagggtttct tcgcgtttca gacgcgagca gataattttg tcgccgttga
    28141 gaatcggtac atctttaatg gctaaatcat gcaggttagg gttctcaacg cgaatattga
    28201 tagtcttgat cagcgcgccg ccattggtgc gtgaagactc gtgctgctga gcttctgtct
    28261 cgacattgac gcggaaaata acccgcaaca tccacatggt gaacaaaatc ccgcaaatgc
    28321 cgaatggata cgccatcgcg taactcatcc ccatctgatc gaccatttcc attggtgtac
    28381 ccaggtcgcg caaaatctgc tgccctgccc ccagcgctgg cgtattggta accgcaccgg
    28441 agaaaatccc cagcactacc ggcagtggaa tatcaaacag tttatgcagg atggcggtaa
    28501 ccagaccacc gatgatgacg atcagaacag caaacaggtt gaggcgtaat ccggagacgc
    28561 gcaatgaggc aaagaagccc ggccctacct gaatcccgat agtataaacg aacaggatca
    28621 ggccaaattc ctgaataaca tgcagcatat cgctacttaa tgtcatcccc gcctgagaaa
    28681 caaaatggcc gacgatgatc ccaccaaaca gcacgccgcc aatacctaat cctatgccgc
    28741 gaaatttgac gttgccgata aacaaaccga cgactgccac caaagccaga atactgaccg
    28801 ttaatgctat atcactcatc gtccatttct cttgagataa cattttaatt gctacggatt
    28861 atggctgaat cggtgaagca gatttgcctt atagcgcaca ttatcacggg aaagaacgtg
    28921 ccgaaatatc ttaaacagtc gaaatttaac gcattgttga gtaagtaaga caaaaaaagc
    28981 cccaccagaa tggcggggca aagagaatag ctagttagct atttaacgcg ggacgttcgc
    29041 tgatagcgat acgctgcgct gcgatgggtt caggctcatt acgaattaaa tcaatatgca
    29101 gtaaaccgtt tacgaaggtt gcgccagaga cttccatatt ttcagccagc gtaaagctca
    29161 ggctaaatgg ctgattcata agcccttgat gcagccattt tttctcttct tttggctgct
    29221 ccggcgtgcc ttttacgctc aggcgcgtac cttccagttg aatctctaaa tcttcctgac
    29281 ggaaacctgc cagcgcaagg gtaatgcggt agtggttatc gtcgcttttc tcaatgttgt
    29341 acggcgggaa gctctggctt tcaccggcgt tttgcagtgc gttggccagt ttgtcaaaac
    29401 cgatccattg acgcatcagt ggggataaat cgaagttacg catagtcatt tctccttcta
    29461 agaagcgagt aagtacctgc aaatccgaag attcgcatat gctccctgac ggcgagcatg
    29521 gagatgtcag gccgcgccag gcggccttag ggaattagtt gatttcgata cggcgcggtt
    29581 ttttcgcttc cggaatcacg cgttcgagat cgatatacag caaaccattt accaggttag
    29641 caccacgaac atgaatgttc tcagctaact ggaatttgcg ttcaaagttg cgttcagcga
    29701 tgccctggta cagataggtg cgctcttttt gttcgtcggc gtgagcacct ttcaccacca
    29761 gcagattatc ctgggcggta atttccagtt cgctctcagc aaaaccagcc acagcgatag
    29821 caatgcggta atggttttcg tctaccagtt caacgttata cggagggtag ccgccattac
    29881 tctggctctg gttgttttct aagtggttaa acaaacggtc aaatccaata gcagaacggt
    29941 aaagcgggga taaatcaaag ttacgcataa tcaatagctc ctgaaatcag cgagaatgta
    30001 agaccttcca caatggacag gtcaggtagc cagaacaccc atcaggcgcg tcctcatcgg
    30061 ctacgatgta aaaatgggtc tggaaatgaa cttttcaagc cttatcagcg gacttttttt
    30121 tgcagtttat ggtctattgc atagactgag ggggcagcac gaaacgttaa agtgcgatag
    30181 ccgccacagt gcgacgtaat gatgatgtta ttttcagcaa gggatcgcta taactcatca
    30241 ggccaacacc cacgatcaac agatgaattt attatgataa gaaatgtgtt gttagcgttc
    30301 atgatatgca gcggaatgac attactcgga ggatgctcca gcgtgatgtc ccataccgga
    30361 gggaaagaag gaacgtatcc cggcacccgc gccagcgcaa ccatgattgg cgacgatgaa
    30421 accaactggg gcactaagtc gctggcgatt ctcgatatgc cgtttaccgc tgtgatggac
    30481 acgcttttac tgccgtggga tgtgttccgc aaagacagct cggtgcgctc gcgcgttgaa
    30541 aaaagcgaag ccaacgcgca agccaccaat gcggttattc caccggccag aatgcctgat
    30601 aactgattta gcgatcagtt tcggtgatcc acagctggcc gccttccatc cacgccagcc
    30661 actgaccatc cggcgagaag accacggcgt ccgcagaagg tgaattggcg tggtgttcgg
    30721 ttaaatactc aacctcgccg ctttgcgcat gggcacaagc aattcgatta tccagcacaa
    30781 agcccaacca ttctcctgac ggatgccagt taaatgcaga ctgaatatcc gttttgttat
    30841 gggttaactg gcgcggctcg ccgccctgtg gcgagataag ccacagttgc acaatgccgt
    30901 tatcatctcg cattaaaaac gcgatttgtg taccctgcgg attacagcgc acccagtggc
    30961 gcgggacgtt gactaacccc ggataagccc gatggtgggt aaaggttaaa cgtcgctgca
    31021 cgacgccacg cggtggcgcg ggcagggttg tttccgttcc gcttaacggc gcatcacctg
    31081 ccgctttcca gccagcttca tcttgcggta actcaacgat aaacagctcc ggcactttct
    31141 cgccctttgg cgaaagtgtg tcgccaataa atgccagcgc gtgatttcct acccatcctt
    31201 cttcataagc acgattgatt tcatcactgc caggctgtgg cgtgggcgtg gttttgctca
    31261 ccagcacgca ccagtggcta ccgctgtatt cacgcggatg ctgcttttgt acgttgaccg
    31321 ggccaaacgg cgcagcaaca ccgacgtttc gcaaatccag cgccggatcg agttcatgca
    31381 ttacatggtc gttataggta aagctcaccc tttcaccgtt cgggctaaag acatgcacat
    31441 ggctgccgcc gcgcagcact cctggcgtat acggcgcggt aatatccatc gcatcaaggt
    31501 tactcatctt gccgccttca acaatcactc cgcgccgatg atggaagtcg taatgccatg
    31561 tttcatcagg attttccggg ccgtggatga aaacatattt ctctgacttc ggatgaacgg
    31621 tcaccacgcc gacgtgtgcg ccctgtgacg cgcgatagat aacctcgacc tcgccggtat
    31681 ggatattcac acgctcaatg gtctcgccgg taaacgacgc gccagaagga cgcacgtcaa
    31741 ataccagcca ctggctgtcg ggcgtccagg tattggtatt ggtgagcagg tgattacggg
    31801 gagcaaaggt tatctgtttc atggcgcggt cctgatacaa aacgggtccc gccatcatac
    31861 ttcacaagga cttcactttc agacaatagt cttttgccat cgtgatgaat gtgagtgaaa
    31921 agatggaaca tttcgacgtg gcgattattg gcctcggccc ggcaggatcg gcgttggcac
    31981 gaaagttagc aggcaaaatg caggtgatcg cgctggataa aaagcaccag tgtggtactg
    32041 aaggtttcag caaaccctgc ggcggtctgc tggcaccgga cgcgcagcga tcttttattc
    32101 gcgatgggct gacgcttcct gtcgatgtga tcgctaatcc gcagattttc agcgtcaaaa
    32161 ccgtcgacgt cgccgcatcg ctcacgcgta actaccagcg aagctatatc aatattaatc
    32221 gccatgcttt cgacttgtgg atgaaatcgc tgatccccgc cagcgttgag gtttatcacg
    32281 acagcctgtg ccgaaaaatc tggcgtgagg atgataaatg gcatgtcatt tttcgtgcag
    32341 acggctggga gcaacatatt accgcccgct atctggtcgg tgccgatggc gcaaactcga
    32401 tggtgcggcg acatctctac ccggatcatc aaatccgtaa atatgtcgct atccagcagt
    32461 ggttcgcgga gaaacatccg gtgccgttct actcctgcat ctttgataat tcgataacta
    32521 actgttattc atgaagtatc agcaaagacg gttattttat ctttggcggt gcctatccaa
    32581 tgaaagacgg tcagacgcgt ttcacgacgc tgaaagagaa aatgagcgcc tttcagttcc
    32641 agtttggtaa gacggtgaaa agcgaaaaat gcacggtgct gtttccctcg cgctggcagg
    32701 attttgtctg cggtaaggac aacgcctttc tgattggtga agcggcggga tttatcagcg
    32761 ccagctcgct ggaggggatt agctatgcgc tggatagcac agacattctg cgttcggtgt
    32821 tactgaagca gccagagaag ctcaataccg cttactggcg cgccacccgc aaactgcgtt
    32881 taaaactctt cggcaagata gtaaaaagcc gatgcctgac cgcaccggct ttaagaaagt
    32941 ggattatgcg cagtggtgtg gcacatattc cacagttgaa ggattagcca acgcgcttca
    33001 catcgcccac cagcaggata taagagagcg cgccaatcaa cgcgacggcg gagatataaa
    33061 ccagtgcagg tgcgaaaccg taaccctgcg ccaggtaccc caccaccagc ggaacggtga
    33121 tgccgcccag accaccggcg aagttaaaca cgccgccggt taaaccaatc aggcgcatcg
    33181 gtgccagaga agaaaccagc gaccaggtaa tcgaagcaaa accgttaccg aagaatgcca
    33241 gcgccatcag gcacataatc atcatcggat cgttagtgta gttagcgccc ataatgcagg
    33301 tggagatcag caagccgcag ataatcggcg ttttacgcgc aaagcccagt gaaaagccct
    33361 tacgtaccag cagatccgct acccagccag agagcaggac gccgacaaac gccgcgagga
    33421 atggcaccgt ggtcataaag cctgctttca gcgccgtgat tcctttttcc tgggttaaat
    33481 agttcgggaa ccaggttaag aaaaaccaca gtgtagaagc caccgcaaat tgcccaagat
    33541 aaacgccgat cagtttacga tggaacacca gtttccagtc tttggctgtt aacggctgac
    33601 gcgcctcttt cttcaccggc gcatcaccat ccaccagacc gccgccatca cgaatgtaat
    33661 ccagttcagc tttgctgata cctttggtca ggcgcggcgg ctgataaacc ttaaaccaaa
    33721 tcagcgacca gataatgccg ataccaccag tgacaatgaa cacccagtgc cagttcaaca
    33781 tctcctgaat ccagatcagc agcggcgtca gaaacgccag accgacaaac tgaccagacg
    33841 tataaaaacc aacggcagaa gcgcgttcat gttccgggaa ccagctggtc accatccggt
    33901 tattggtcgg gaaagcaggc gcttcgaaaa taccggttat cgcgcgcaga ccaattaatg
    33961 acattaagcc cgtggcaaag ccctggaata aagtcgccac tgaccagcca aatatcgcaa
    34021 taaaataagt cacgcgagaa cctacgcgat ctaaaaacca accgccgggg atctgacata
    34081 gcgtataaag ccaggcgaag gccgaaaata catagcccat ttccgctttg gtaatgccga
    34141 actcttcctg aatatgggcg gaagccacgg ccaggttggc gcggtcgaca taacaaatga
    34201 ctaccgtaat aaagatcatc accagcgtca gataacgccg acgccccggc tttgctgcat
    34261 taacgggaat atccatagcg agctttctcc agattttggg catagcgaag ccgctcacca
    34321 tgccctgtaa tttacagagg gttatatttt tgtattgctg ttttagtgcc cgatgagggg
    34381 cttacgtggc aggaattacc actctgctac gctgttatct tcatgacgcc agagcggatt
    34441 acgccagtcc ggggcatttt tactgaactc aatcacttta gcttcgtcga tttccacgcc
    34501 taagcccggt ttcgttaacg gtttaaagaa gccgccgacc atgctgaagt cttctttgtt
    34561 tttcacaaag tcgagtaact ccgcgccttt gttgtaatga attcccatac tttgttcctg
    34621 aagtacggcg ttataggaaa caaagtcgat atgcaggcaa gccgccagtg caataggtcc
    34681 gagcggacag tgcggcgcaa gggtcacgtc ataggcttct gccattccgg cgattttgta
    34741 gcattcggta ataccgcccg cgtgggagag atccggttgc agaatcgaaa taccacctgc
    34801 ctccagcacg cgtttaaaat cgaagcgtga gaacatgcgt tcacccgccg ccagtggaat
    34861 atgcgtttgt gccgccagtt tcgggtagta ttcggcttgt tccgccagca ccggctcctc
    34921 aataaacagc gggcgatacg gctccagttc tttaatcagc actttcgcca tcggcgcgct
    34981 gacgcgaccg tggaaatcaa gaccaaactc aatctgattg ccaaaagctt cacgaatttg
    35041 tgccacggtg ttaaccgccg catctaccgc gcgggagtta tcaattagcc ccagttcttc
    35101 acaaccgttc agtttgaagg tatcgaagcc gatttcgcgt agcgttttaa tgccgtcgat
    35161 aacatccgcc ggacgatcgc cgccaaccca actgtaggct ttaattttgt cgcgaaccag
    35221 gccgcccatc agttgccaga ccggcgcatt cagcacttta cctttgatat cccataacgc
    35281 ctggtcaatc ccggcgatgg cgctcatcag gatcggaccg ccgcgataga atccggcgcg
    35341 atacatcact tgccataagt cattgatgcg cgatggatcc tgaccaatca aatagtcacc
    35401 cagctcgtga actgccgctt ccaccgtacg ggcgcggcct tcgatcacgg gctcgcccca
    35461 accgaccacg ccttcatcgg tttcaatttt caggaacatc cagcggggag gtaaacgata
    35521 cgtggtaatt ttggtgattt tcattgcact gcctctcgat acgccttaac aaatgctgct
    35581 gcctgctgcg cggtgcgctc tacggattgc ccggcgcgat agagatcgct gcctaagccc
    35641 gcccctgcac aacctgcgtc tatccactgc gccaggtttt ctggcgtcac gccgccaacg
    35701 gcaaagactg cgatgtccga tggcaatacc gcttttaacg ctttgatgta ttgcggacca
    35761 aaagccgatg acggaaatat tttcagcgcc tgcgcgcccg cttcgagcgc ggtaaaggct
    35821 tcggtcgccg tcgcgcagcc ggggcagacg gtcatgccgt agcccaccgc acggcggatc
    35881 acttcactat ggatattggg cgtaacgatg agctgacagc ccatcctggc gagcgcatcg
    35941 acctgttcag gtttcagtac cgtacctgcg ccaatcaacg ccttgtcgcc gtacgcatca
    36001 acgatggcgg gaatgctttg ctcccattgt ggggaattca gcgggatttc aaccgcgtcg
    36061 aacccggcgt caatcaccgc gccaacatgc gccagcgcct cgtcgggcgt aataccgcgc
    36121 aaaatggcga tcagcgggag tttagtttgc cactgcatga gcgatgctcc ttataccagc
    36181 ctgaaatgcc gtgtcgcccg ccaccgccgt cacgtcgcaa cccatcgcct gaaaggcttg
    36241 ctggtagcgc gcggtcagcg atgttccggc gacaagggtg atggcgtgtt gatgggccac
    36301 atagtcgcgc atactggcga cctctgcgcc aatcaacaaa ccagagagaa attcgctgac
    36361 ctgttcgcgg ggaagtgttc ccagcacatg cgaggcgcga acttcaaaaa gctgcggcaa
    36421 tatggcgggc gtattaagac cacgctcaag gccagctgtg aaggcatcgg cagagttttc
    36481 ctgcggcggc aaacctgcgc caatcaatga gtgatttaac agtaaatgat gtaattcacc
    36541 ggtcatcacg gtgcgaaaat cgttgatttg ctggctatcg gcctgcaccc atttgcaatg
    36601 ggttccgggc atgacataaa gagaggaagg agccagagct cgcgcgccga tcaattgtgt
    36661 ttcttcgccg cgcatcacat tgtggttatc gtcatgagag acacataatc cgggaataat
    36721 ccagatattg tcgccaactg acgttaattg ttcgccaata gacgaaaaac aggcaggaac
    36781 agataaatac ggtgcaactt tccagccgac gttgctgcca accattcctg ccattaccac
    36841 tggcgttttc tcttcacgcc agtcggtcgt gacttctgct aacaccgcag ccggagattt
    36901 tccgttcagg cgcgtgacgc ctgcttctga ttgcctgctc tccaggcagt ggtcgccctg
    36961 ataaagccag gcgcgcagat tggtcgatcc ccagtcaatt gcgatgtagc gagctgtcat
    37021 gtgatttcct ttaaccttcg tgtcgagctg gcgatcatgg taagcgccgc ctgctctgcc
    37081 gcatcgccgt cctgatgtcg tatcgcatcg aacagcgcct tatgttcctg gagcgtttgc
    37141 ggcatgttgg cctcatcgcc catccaggtt cgttcaaaaa ccgcccgctg cagcgaactg
    37201 atcgcaatgc taagttgctg taacaccggg ttatgcaccg actgcagcac cgcctcgtgg
    37261 tagcgaatat ccgcttcgtt aaacgcttcg cggtcctgat tgttggcaat catctcgttc
    37321 agcgccgatt caatctgcgc cagatcgctg gaagtcgcgc gctctgctgc ccaacgggca
    37381 atcgccggtt ccaccagatt tcgcacttcg ctcatggcac tgataagccg tgggtcgtag
    37441 tcattttcca gcacccattg cagtacgtca gtgtcgaggt aattccactg gttacgcggt
    37501 gccacaaacg ccccgcgata acgtttcatt tcaatcagcc gcttcgccat cagcgaacgg
    37561 aacacctcac ggatgatgtt gcgcgaggtt gcaaactcct cacagagttc cgcctcagcc
    37621 ggaagcggcg agcctggcac gtatttgccg tgaacgatct gtttacccag cgtaatgaca
    37681 atgcgatcgg ttttattgag agtcatggag agtccttgtg ctctgtatgt tcttctctac
    37741 tttaccccga tcgatgcata acgcggcaac tttgtagtac cagcgtgatg acgttcgcgt
    37801 ttgccgtgcg tgtaatgtag tacaaactta tattgttgta ctacaattta gatcacaaaa
    37861 agaacaatgc ataaaaaaat gacatgcgtc gggcagaaat ctgaaaaggg atatcaggcg
    37921 ctaaacagga gggaaagaag agtatgcttt caacggctta gctactcgtt taaaggatta
    37981 atcatgaagt tgaattttaa gggatttttt aaggctgccg gtttattccc actggcgctg
    38041 atgctttcag gctgtatctc gtatgctctg gtttcccata ccgcaaaggg tagttcagga
    38101 aagtatcaat cgcagtcaga caccatcact gggctatcgc aggcaaaaga tagtaatgga
    38161 acaaaaggct atgtttttgt aggggaatcg ctggattacc ttatcactga tggtgccgat
    38221 gacatcgtta agatgctcaa tgatccagca cttaaccggc acaatattca ggttgccgat
    38281 gacgcaagat ttgttttaaa tgcggggaaa aagaaattta ccggcacaat atcgctttac
    38341 tactactgga ataacgaaga agaaaaggca ctggcaacgc attatggttt tgcctgtggt
    38401 gttcaacact gtaccaggtc actggaaaac ctaaaaggca caatccatga gaaaaataaa
    38461 aacatggatt actcaaaggt gatggcgttc taccatccat ttaaagtgcg attttatgaa
    38521 tactattcac ccagaggcat tccggatggt gtttccgcag cattactgcc agtgactgtt
    38581 acgctggaca tcattactgc accgctgcaa tttctggttg tatatgcagt aaaccaataa
    38641 tcagtaagcg ggcaaacgcg tttatgctgt ttgcccgccc acagattaat tcagcacata
    38701 cttctcaata gcaaacgcca cgccatcttc aaggttagat ttggtgacaa agttcgccac
    38761 ttctttcact gaaggaatag cgttatccat cgccacaccg acgcctgcat attcaatcat
    38821 tgcgatatcg ttttcctgat cgccaatcgc catgatttct tccggtttaa tacctaacac
    38881 gtcggccagt gatttcaccc ccgtaccttt gttaacgcgt ttatcgagga tttcgaggaa
    38941 gtacggcgca cttttcagca cggtatattt ctctttcact tcctgcggaa tacgcgcgat
    39001 agcctggtcg aggatggcgg gttcatcaat catcatcact ttcaggaact gggtattggg
    39061 gtccattttc tccgcttcgc agaacaccag cggaatggtg gcaacgaagg attcatgcac
    39121 cgtgtagtag ctgatatcac ggttggcggt gtacagcgtg gtgcggtcca gggcgtggaa
    39181 atgagaaccg acttcgcgag agagtttttc caggaaacga tagtcgtcat agctgagagc
    39241 agtttgcgcc acggtgctac catcagcggc cttctgtacc agcgcgccgt tataagtaat
    39301 gcagtagtcg cccggctgtt ccatatgcag ctctttcagg tagttgtgca cacctgcata
    39361 cgggcgaccc gtcgttagca cgacattcac gccacgggcg cgagctgcgg caatcgcatt
    39421 tttaacggcg ggtgaaatgg tgtgatcggg cagcagaagg gtgccatcca tatcgatagc
    39481 aatgagttta atagccatga gttccccagg tagattggtt cctgacccat gctaacgcga
    39541 ttccgctcaa aaatcagtac aacacccgag ggaaaagggg gatgcaacgc gcgttgcgtg
    39601 ctcccttttt gcttagcgga agagtttccc tttcagcagt tccatgcctg cggaaagcag
    39661 atcgttattg gcttgtggtg acacttcacc ttgcggtgag agcgcatcaa taatcttcgg
    39721 caattgttct gccagtaaac tggaagctgt actggtatcc acgccaagtt tttgcccgag
    39781 atcggacacc gcatttgtgc cgagcgccga ttccagttgc tcgccactaa ccgattgatt
    39841 gccctgttga ttactcagcc aggttgagag aatggcccct aagccgccac tttgcagttt
    39901 ttccagcagc acctgaatgc cgccctgctc ctcaacccaa cttaaaatag cctgatattt
    39961 ccccgcatcg cctttcagaa aggcaccgac aacttcatca aaaagcccca tgataatcac
    40021 ctgtaaagcg ttacgtgttg acccaaaaag tatagatttg cgggatgata attgcggatt
    40081 gcagaaataa aaagggcgga gatgatctcc gcccttttct tatagcttct tgccggatgc
    40141 ggcgtgaacg ccttatccgg cctacaaaat catgaaaatt caatatattg caagattttc
    40201 gtaggcctga taagcgtagc gcatcaggca cgctcgcatg gttagcgcca ttaaatatcg
    40261 atattcgccg ctttcagggc gttctcttca ataaacgcac ggcgcggttc aacggcgtcg
    40321 cccatcagcg tggtgaacaa ctggtcggca gcaatcgcat ctttaacggt aacgcgcagc
    40381 atacgacgac tttccgggtc catagtggtt tcccacagct gttccgggtt catctcgccc
    40441 agacctttat aacgctggat ggagaggccg cgacgggact ctttcaccag ccagtccagc
    40501 gcctgctcga agctggctac cggctgacga cgctcgccac gttcgataaa cgcatcttct
    40561 tccagcaagc cacgcagttt ctcacccagc gtgcagatac gacgatattc gccaccggtg
    40621 ataaactcgt gatccagcgg atagtcagta tccacaccgt gggtacgcac gcgaacaatc
    40681 ggctcgaaca ggttttgctc agcattggtg tgaacatcaa acttccactg gctgccgtgc
    40741 tgttctttgt cgttcagttc gctgaccagc gcgttcaccc agcgggtaac ggtctgctca
    40801 tcagaaaggt cagcttccgt caacgtcggc tgatagataa gctctttcag cattgctttc
    40861 ggataacgac gctccatacg attgatcatt ttctgcgtcg cgttgtactc agataccagt
    40921 ttctctaacg cttcgccagc caatgccggt gcactggcgt tggtgtgcag cgttgcgccg
    40981 tccagcgcga tagagatctg gtactgatcc atcgcttcgt cgtctttaat gtactgttcc
    41041 tgcttgcctt tcttcacttt gtacagcggc ggctgagcga tgtagacgtg accgcgttca
    41101 acgatttccg gcatctgacg atagaagaag gtcaacagca gcgtacgaat gtgcgagccg
    41161 tcgacgtccg catcggtcat gatgatgatg ctgtgataac gcagtttgtc cgggttgtac
    41221 tcgtcacgac cgataccaca gccaagcgcg gtgataagcg tcgccacttc ctgagaagag
    41281 agcatcttat cgaagcgcgc tttctcgacg ttgaggattt tacccttcag cggcagaatc
    41341 gcctggttct tgcggttacg cccctgcttc gcagagccgc ccgcggagtc cccttccacc
    41401 aggtacagtt cggaaagcgc cggatcgcgt tcctggcagt ctgccagttt gcccggcagg
    41461 cccgctaagt cgagcgcacc tttacggcgg gtcatttcac gcgcgcgacg cgccgcttca
    41521 cgggcacggg cagcatcgat aattttgcca accacgattt tcgcgtcggt tgggttttcc
    41581 agcaggtatt ctgccagcag ttcgttcatc tgctgttcaa ccgccgattt cacctcagaa
    41641 gaaaccagtt tgtctttggt ctgggaggag aatttcgggt ccggcacttt cacggaaacg
    41701 accgcaatca ggccttcacg cgcatcgtca ccggtggcgc tgactttggc ttttttgctg
    41761 tagccttctt tgtccatgta ggcgttcagg gtacgggtca tcgccgcacg gaagcctgcc
    41821 aggtgagtac cgccgtcacg ctgcggaatg ttgttggtaa agcagtagat gttttcctgg
    41881 aagccatcgt tccactgcaa cgccacttcg acgccaatac cgtctttttc agtggagaag
    41941 tagaagatat tcgggtggat cggcgttttg ttcttgttca gatattcaac gaacgccttg
    42001 atgccgcctt catagtggaa gtggtcttct ttgccgtcgc gcttgtcgcg cagacgaatg
    42061 gaaacgccgg agttgaggaa cgacaactca cgcagacgtt tcgccagaat ttcatattcg
    42121 aactcggtca cattggtgaa ggtttcgagg ctgggccaga aacgcaccat ggtgccggtt
    42181 ttttcagtct cgccggtaac cgccagcggg gcctgcggta caccgtgttc gtagatctga
    42241 cggtgaattt taccctcgcg ctggataacc agctccagtt tttgcgacag ggcgtttact
    42301 accgaaacac caacgccgtg cagaccgccg gacactttat aggagttatc gtcaaattta
    42361 ccgcctgcgt gcagaacggt catgatcact tccgccgccg atacgccctc ttccgggtga
    42421 ataccggtcg gaatgccgcg cccgtcatcc tgtacagaga cagagttatc ggcgtgaatg
    42481 gtgacgataa tttctttaca gtgacccgcg agcgcttcgt cgatagcgtt atctaccacc
    42541 tcgaatacca tgtggtgcag accggtgccg tcatccgtgt cgccgatata catacccggg
    42601 cgcttacgca ccgcatccag ccctttcagg actttgatac tggaggagtc ataagaattc
    42661 gacatcaacg tttctcgctc atttatactt gggttaatcc gttattttac ccttttccac
    42721 ggtaaacatc ttcgaatttt cgtccgacat gtctataacg tgttcagcac tgatcgcgct
    42781 gacaaagacc tgtgattgcg tcgcttttaa gcggctggca agcagcccgc gacgctcatc
    42841 atcaagctca gaggcaaaat catctatcag gtagagacac cgccgcccgc tttcacgggt
    42901 gaggaactct ccttgcgcca gacgtaaggc gcacatcaac agcttaagct gcccacgcga
    42961 taaggtatct tccaccggcg caccgtcggc gcgaatgcgt aagtccgctt tgtgcgggcc
    43021 gtgcgcggtg taggttagct ggcgatcgcg ttcaaaatta cgttccagca cctcagcata
    43081 ttctgtctct ttctcccagc cgcgctggaa agagaaagtc agagaaaact cagggagaaa
    43141 ttgcttacag gtatcagcca tatcggccgc gataccggcg ctatactccg cgcgccaggt
    43201 gctgatttgc tccgccagcg ggatcagctc tttatcccac gggcgtagct gttcgtaacg
    43261 tgtcacctgg cgcagcgccg cattgcgctg cttgagcaat cgcttgagat tgctccaggc
    43321 ggtgaaaaat ccgggttcgt tgtgaaagca tccccagtcg aggaatgctc ttctgtattt
    43381 ggggccgccg ttgagtaaag taaacccttc tggcgttatc aactgcattg gcatcaggtg
    43441 cgccagttcc gcgaccttat gcccgtctgt accgtcgatg cggactttgc tgtcgccctg
    43501 tttgtctttg gttaagccaa tcgctgtctc gcgctcttcg ccctgtaatc gcccgtggag
    43561 aacaaacgcc tcctgctcat ggcgaatgac gcgaccaatc tgcaaactgc gaaacgcccg
    43621 accatggccg agcgtataga tggcttccag cacgctggtt ttgccactgc cgttggcacc
    43681 taccagaaag ttaaagccgg gagataaggc gagatccgcg gtttcaatgt tgcggaaatc
    43741 gcggatcaac aagcgggtga gggacattac agtctcattg gcatgacaac ataagccgcg
    43801 ctctggctgg ccgcatcttc aatctgcacg ctggaaaccg aatcggtcag catcatgcgg
    43861 acgttttcgc atttcagcgc gttcagaaca tccagcacat aactgacgtt gaagccgatt
    43921 tccatctccg caccgctata ggtaacgtcg aggatctctt ccgcttcttc ctgttccggg
    43981 ttgttggcgg tgattttcag ctggttttcg ctgacataaa gacgtacgcc gcggaatttc
    44041 tcgttagaga gaatcgccgc gcgagcaaac gcctgcttga gcagatcgca gccagcttcc
    44101 agatgtttgt ccgggttctt cggcagaacg cggcgataat ccgggaagcg accatccacc
    44161 agtttggagg tgaagataaa gtcgccaacg tgggcgcgaa tgttgttgct gccaatctgt
    44221 acgcgcagcg gattgtcgcc gccgtcgagc atacgcatca gttcaatcac gcctttacgc
    44281 ggtacgatca ccgaatggct tggcaaagat tgaccaattg gcattgaaca gaccgccaga
    44341 cggtggccgt cggttgccac ggtgcgcagt tcttcacctt cggtttcaaa cagcatacca
    44401 tttaagtaat agcgaacgtc ctgatgcgcc atagaaaact gggtcgcttc aatcagacgc
    44461 ttcatcgttg cctgcggcag ggtaaattcg acttcactct gccagtcatc gaggttcggg
    44521 aaatccgccg ctggcagggt agacagcgaa aaacggctac gcccggagcg taccagcatc
    44581 cgttcacctt ccagctgcac ggcaatttcc gcgccttcag gcagaccacg gcagatatca
    44641 aagaatttgc gcgccggaac ggtcgtcgct cctggctcgt gtggctgaac cagcgcaaca
    44701 cgtgccacca tttccatctc gagatcagta ccggtcagcg acaacgtacc gtcagcaacc
    44761 tgtaacagca gattaccgag aatcggtagc gtaggacgac cacctaacgg accgctcacc
    44821 tgttgtagcg gttttaataa atgctcacgt tctacggtaa atttcatagg tttacgatga
    44881 caatgttctg attaaatttg aaaaatcttc tttgatatcg tggctctctt cacgcaactg
    44941 ctcgatctta cggcaggcat gaagcaccgt cgtgtggtca cggccaccaa acgcatcgcc
    45001 aatctccggc agactgtggt tagtcagctc tttcgccagc gccatcgcca tctggcgcgg
    45061 acgcgccacc gagcgggatc gacgcttgga aaggagatcc gcgactttga tcttgtagta
    45121 ctccgccacc gtcttctgaa tattgtcgat ggtgaccagt ttttcctgca atgccagcaa
    45181 gtcgcgcagc gcctcacgca cgaagtcgat ggtgatcgcc cgtccggtaa agttggcatt
    45241 ggcaatgacg cggttcagcg ccccttccag ctcacgtacg ttagatcgta gacgcttggc
    45301 gataaagaac gccacttcgc ccggcaaacg aatgtcgttt tcgtcggcct ttttcatcag
    45361 gatcgccaca cgggtttcca gctctggcgg ttcgatcgcc acagtcagtc cccaaccgaa
    45421 gcgggatttc aaacgatcct caacgccgtt gatctctttc ggatagcgat ccgaggtgag
    45481 aatgatctgt tgattacctt ccagcagggc gttgaaggtg tggaaaaact cttcctgaga
    45541 tcgttcttta ttagcaaaaa actgaatatc gtcgatcagc agtgcatcta cggaacggta
    45601 gtagcgttta aactcttcga tcgcgttgtt ttgcagggct ttaaccatgt cctgaacaaa
    45661 gcgctcggag tgcatataaa ccactttggc attcggcttg cgcgccataa tgccgttacc
    45721 caccgcatgc agcaggtgag ttttacccag acccgtgccg ccataaagga acaacgggtt
    45781 ataggcaccg ccagggttat ccgccacctg gcgagccgcc gcgcgcgcca gttggttaga
    45841 tttaccttca acgaagttat caaacgtgtg tttgacgttt acgttagaac gataggtcgg
    45901 ttctgccggg gccgggacgt tatcccaacc tgagcgcgta gaaggcgcag cacgttgcgg
    45961 ctgcgtttgc gccacctgtg caggggccgc gacgttgctc gtcactgccg cttgtggcgt
    46021 ttgcgtcacc ggtttggtgc cgacttcaaa acgcagctgt ggggcatccg ctccgcagaa
    46081 actggttagc agtccattga tattattaag gtacttgtcc cgtacccaat cgaggacaaa
    46141 acggtttggc gcgtacaggg ccagcgtgtt atcgctcagt tccgcctgca atgggcgtat
    46201 ccacatactg aattctgtgg ctggtaactc atcctgcaat cgggcaagac actgctgcca
    46261 aagcgaaagt gacacggcgg actccactcg aacaaaagtc gataatgact aaggctgaaa
    46321 cattcatgat tgttgacgta cgtcgaaaag accctgcttg agggtgacgc acgaaccgct
    46381 gtctgcggtt atatgcccga tcaagatcct gcaaaacgat cgggaccgcg gatcatagcc
    46441 taaactgcgc aagagatctt ctgtttctca cagattttcc cgatttatcc acaggacttt
    46501 ccagaactcg ctaagtgtaa acgatcctgc cgcgaggcgg gcacgattta cgccgcatat
    46561 tggaaaattt aatgaccata gacaaaaatt ggcttaatcg atctaataaa gatccaggac
    46621 gatccttgcg ctttacccat cagcccgtat aatcctccac ccggcgcgcc atgctggttt
    46681 ccactggtgt gaggtcgtac attttccctg cgaaaaggtg cggaaaagcg cggtaaataa
    46741 ggaaagagaa ttgactccgg agtgtacaat tattacaatc cggcctcttt aatcacccat
    46801 ggcttcggtg tccatcgttt catttttcgg cggatatcca ataaagccat tgaatttatt
    46861 caagtttagg tagaaatcgc catgaaacgc acttttcaac cgtctgtact gaagcgcaac
    46921 cgttctcacg gcttccgtgc tcgtatggct actaaaaatg gtcgtcaggt tctggcacgt
    46981 cgtcgtgcta aaggccgcgc tcgtctgacc gtttctaagt aataaagcta acccctgagt
    47041 ggttaagctc gcatttccca gggagttacg cttgttaact cccagtcaat tcacattcgt
    47101 cttccagcag ccacaacggg ctggcacgcc gcaaattacc attctcggcc gcctgaattc
    47161 gctggggcat ccccgtatcg gtcttacagt cgccaagaaa aacgttcgac gcgcccatga
    47221 acgcaatcgg attaaacgtc tgacgcgtga aagcttccgt ctgcgccaac atgaactccc
    47281 ggctatggat ttcgtggtgg tggcgaaaaa aggggttgcc gacctcgata accgtgctct
    47341 ctcggaagcg ttggaaaaat tatggcgccg ccactgtcgc ctggctcgcg ggtcctgata
    47401 gccctcattc gggtctatca acgcctgatt agtccgctac tcgggccgca ttgtcgtttc
    47461 actccaacct gttcaagcta cggaattgag gcattgcgca ggtttggagt gataaaaggc
    47521 agttggttga cggtgaaacg cgtattaaaa tgccaccctt tacaccctgg tggtgacgat
    47581 cccgtcccgc ccggaccatt tgataccaga gaacactaac gatggattcg caacgcaatc
    47641 ttttagtcat cgctttgctg ttcgtgtctt tcatgatctg gcaagcctgg gagcaggata
    47701 aaaacccgca acctcaggcc caacagacca cgcagacaac gaccaccgca gcgggtagcg
    47761 ccgccgacca gggcgtaccg gccagtggcc aggggaaact gatctcggtt aagaccgacg
    47821 tgcttgatct gaccatcaac acccgtggtg gtgatgttga gcaagctctg ctgcctgctt
    47881 acccgaaaga gctgaactct acccagccgt tccagctgtt ggaaacttca ccgcagttta
    47941 tttatcaggc acagagcggt ctgaccggtc gtgatggccc ggataacccg gctaacggcc
    48001 cgcgtccgct gtataacgtt gaaaaagacg cttatgtgct ggctgaaggt caaaacgaac
    48061 tgcaggtgcc gatgacgtat accgacgcgg caggcaacac gtttaccaaa acgtttgtcc
    48121 tgaaacgtgg tgattacgct gtcaacgtca actacaacgt gcagaacgct ggcgagaaac
    48181 cgctggaaat ctcctcgttt ggtcagttga agcaatccat cactctgcca ccgcatctcg
    48241 ataccggaag cagcaacttc gcactgcaca ccttccgtgg cgcggcgtac tccacgcctg
    48301 acgagaagta tgagaaatac aagttcgata ccattgccga taacgaaaac ctgaacatct
    48361 cttcgaaagg tggttgggtg gcgatgctgc aacagtattt cgcgacggcg tggatcccgc
    48421 ataacgacgg taccaacaac ttctataccg ctaatctggg taacggcatc gccgctatcg
    48481 gctataaatc tcagccggta ctggttcagc ctggtcagac tggcgcgatg aacagcaccc
    48541 tgtgggttgg cccggaaatc caggacaaaa tggcagctgt tgctccgcac ctggatctga
    48601 ccgttgatta cggttggttg tggttcatct ctcagccgct gttcaaactg ctgaaatgga
    48661 tccatagctt tgtgggtaac tggggcttct ccattatcat catcaccttt atcgttcgtg
    48721 gcatcatgta cccgctgacc aaagcgcagt acacctccat ggcgaagatg cgtatgttgc
    48781 agccgaagat tcaggcaatg cgtgagcgtc tgggcgatga caaacagcgt atcagccagg
    48841 aaatgatggc gctgtacaaa gctgagaagg ttaacccgct gggcggctgc ttcccgctgc
    48901 tgatccagat gccaatcttc ctggcgttgt actacatgct gatgggttcc gttgaactgc
    48961 gtcaggcacc gtttgcactg tggatccacg acctgtcggc acaggacccg tactacatcc
    49021 tgccgatcct gatgggcgta acgatgttct tcattcagaa gatgtcgccg accacagtga
    49081 ccgacccgat gcagcagaag atcatgacct ttatgccggt catcttcacc gtgttcttcc
    49141 tgtggttccc gtcaggtctg gtgctgtact atatcgtcag caacctggta accattattc
    49201 agcagcagct gatttaccgt ggtctggaaa aacgtggcct gcatagccgc gagaagaaaa
    49261 aatcctgatt cggtgagttt tcgctaaaat aagggcggtc agttgaccgc cttttttctt
    49321 ttcgtagggc ggataagcac cgcgcatccg ccacacaaag caacaggaac atcatgagcg
    49381 ataatgacac tatcgtagcc caggccacgc ctccgggacg tggcggcgtt ggcatcctgc
    49441 gcatctccgg cttcaaagcc cgtgaagttg ccgaaaccgt gctgggtaaa ctgcctaagc
    49501 cgcgctacgc cgattatctt ccgtttaaag acgccgacgg cagcgtgctc gatcagggga
    49561 ttgcgctatg gttccctggc ccgaactcgt tcaccggcga agatgtgctg gaactgcaag
    49621 gtcatggcgg tccggtgatc ctcgacctgc tgttaaaacg cattctgacc attcccggcc
    49681 tgcggattgc tcgccctggt gagttttccg aacgcgcgtt tcttaacgat aaacttgact
    49741 tagcccaggc cgaggcgatt gccgatctta tcgacgccag ttcggaacag gcggcccgtt
    49801 cggcacttaa ctcgctgcaa ggcgcattct ccgcacgggt taatcatctg gtagaagccc
    49861 tcacccactt gcgcatttac gtcgaagcgg caattgattt ccccgatgaa gagatcgatt
    49921 tcctctccga cggaaaaatt gaagcccagc tcaatgacgt tattgccgat cttgatgcag
    49981 tgcgtgctga agcacgtcag ggtagtttgt tgcgcgaagg gatgaaagtg gtgattgccg
    50041 gacgtcctaa cgccggtaaa tcgagcctgt taaacgcgct ggcggggcgt gaagcggcaa
    50101 tcgtaaccga tatcgccgga actacgcgtg acgtgctgcg tgagcatatc cacattgacg
    50161 gaatgccgct gcatatcatc gataccgccg ggctacgtga agccagtgac gaagtagaac
    50221 gtattggtat cgagcgcgcg tggcaggaaa ttgaacaggc cgaccgcgtg ctgtttatgg
    50281 tcgatggcac cacaacagac gccgtggatc cggcagagat ctggccggaa tttattgccc
    50341 gtctgccagc gaaactgccg atcaccgtgg tgcgcaataa agccgatatc accggcgaaa
    50401 cgctgggaat gagtgaagtg aacggtcacg cgttaattcg tctctcggca aggactggtg
    50461 aaggcgtgga cgtgctgcgt aaccatctca aacagagcat gggctttgac accaacatgg
    50521 aaggcggctt cctggcgcgt cgtcgccacc tacaggcgct ggaacaggca gcggaacatc
    50581 tacaacaggg caaagcgcaa ctgttgggag cctgggcagg tgaactgctg gcggaagagt
    50641 tgcgtctggc acagcagaac ttaagcgaaa tcaccgggga atttacttca gacgacctgc
    50701 tggggcggat tttctccagc ttctgtattg gtaagtaacc gcgcttacga agccgcattc
    50761 tgactgtcag atgcggcttc gcttcattgt taccactcct gttattcctc aacccttttt
    50821 ttaaacatta aaattcttac gtaatttata atctttaaaa aaagcattta atattgctcc
    50881 ccgaacgatt gtgattcgat tcacatttaa acaatttcag aatagacaaa aactctgagt
    50941 gtaataatgt agcctcgtgt cttgcgagga taagtgcatt atgaatatct tacatatatg
    51001 tgtgacctca aaatggttca atattgacaa caaaattgtc gatcaccgcc cttgatttgc
    51061 ccttctgtag ccatcaccag agccaaaccg attagattca atgtgatcta ttggtttgct
    51121 atatcttaat tttgcctttt gcaaaggtca tctctcgttt atttacttgt tttagtaaat
    51181 gatggtgctt gcatatatat ctggcgaatt aatcggtata gcagatgtaa tattcacagg
    51241 gatcactgta attaaaataa atgaaggatt atgtaatgga aaactttaaa catctccctg
    51301 aaccgttccg cattcgtgtt attgagccag taaaacgtac cactcgcgct tatcgtgaag
    51361 aggcaattat taaatccggt atgaacccgt tcctgctgga tagcgaagat gtgtttatcg
    51421 atttactgac cgacagcggc accggggcgg tgacgcagag catgcaggct gcgatgatgc
    51481 gcggcgacga agcctacagc ggcagtcgta gctactatgc gttagccgag tcagtgaaaa
    51541 atatctttgg ttatcaatac accattccga ctcaccaggg ccgtggcgca gagcaaatct
    51601 atattccggt actgattaaa aaacgcgagc aggaaaaagg cctggatcgc agcaaaatgg
    51661 tggcgttctc taactatttc tttgatacca cgcagggcca tagccagatc aacggctgta
    51721 ccgtgcgtaa cgtctatatc aaagaagcct tcgatacggg cgtgcgttac gactttaaag
    51781 gcaactttga ccttgaggga ttagaacgcg gtattgaaga agttggtccg aataacgtgc
    51841 cgtatatcgt tgcaaccatc accagtaact ctgcaggtgg tcagccggtt tcactggcaa
    51901 acttaaaagc gatgtacagc atcgcgaaga aatacgatat tccggtggta atggactccg
    51961 cgcgctttgc tgaaaacgcc tatttcatca agcagcgtga agcagaatac aaagactgga
    52021 ccatcgagca gatcacccgc gaaacctaca aatatgccga tatgctggcg atgtccgcca
    52081 agaaagatgc gatggtgccg atgggcggcc tgctgtgcat gaaagacgac agcttctttg
    52141 atgtgtacac cgagtgcaga accctttgcg tggtgcagga aggcttcccg acatatggcg
    52201 gcctggaagg cggcgcgatg gagcgtctgg cggtaggtct gtatgacggc atgaatctcg
    52261 actggctggc ttatcgtatc gcgcaggtac agtatctggt cgatggtctg gaagagattg
    52321 gcgttgtctg ccagcaggcg ggcggtcacg cggcattcgt tgatgccggt aaactgttgc
    52381 cgcatatccc ggcagaccag ttcccggcac aggcgctggc ctgcgagctg tataaagtcg
    52441 ccggtatccg tgcggtagaa attggctctt tcctgttagg ccgcgatccg aaaaccggta
    52501 aacaactgcc atgcccggct gaactgctgc gtttaaccat tccgcgcgca acatatactc
    52561 aaacacatat ggacttcatt attgaagcct ttaaacatgt gaaagagaac gcggcgaata
    52621 ttaaaggatt aacctttacg tacgaaccga aagtattgcg tcacttcacc gcaaaactta
    52681 aagaagttta attaatacta cagagtggct ataaggatgt tagccactct cttaccctac
    52741 atcctcaata acaaaaatag ccttcctcta aaggtggcat catgactgat caagctgaaa
    52801 aaaagcactc tgcattttgg ggtgttatgg ttatagcagg tacagtaatt ggtggaggta
    52861 tgtttgcttt acctgttgat cttgccggtg cctggttttt ctggggtgcc tttatcctta
    52921 tcattgcctg gttttcaatg cttcattccg ggttattgtt attagaagca aatttaaatt
    52981 atcccgtcgg ctccagtttt aacaccatca ccaaagattt aatcggtaac acctggaaca
    53041 ttatcagcgg tattaccgtt gccttcgttc tctatatcct cacttatgcc tatatctctg
    53101 ctaatggtgc gatcattagt gaaacgatat caatgaattt gggttatcac gctaatccac
    53161 gtattgtcgg gatctgcaca gccattttcg ttgccagcgt attgtggtta agttcgttag
    53221 ccgccagtcg tattacctca ttgttcctcg ggctgaagat tatctccttt gtgatcgtgt
    53281 ttggttcttt tttcttccag gtcgattact ccattctgcg cgacgccacc agctccactg
    53341 cgggaacgtc ttacttcccg tatatcttta tggctttgcc ggtgtgtctg gcgtcatttg
    53401 gtttccacgg caatattccc agcctgatta tttgctatgg aaaacgcaaa gataagttaa
    53461 tcaaaagcgt ggtatttggt tcgctgctgg cgctggtgat ttatctcttc tggctctatt
    53521 gcaccatggg gaatattccg cgagaaagct ttaaggcgat tatatcctca ggcggcaacg
    53581 ttgattcgct ggtgaaatcg ttcctcggca ccaaacagca cggcattatc gagttttgcc
    53641 tgctggtgtt ctctaactta gctgttgcca gttcgttctt tggtgtcacg ctggggttgt
    53701 tcgattatct ggcggacctg tttaagattg ataactccca cggcgggcgt ttcaaaaccg
    53761 tgctgttaac cttcctgcca cctgcgttgt tgtatctgat cttcccgaac ggctttattt
    53821 acgggatcgg cggtgccggg ctgtgcgcca ccatctgggc ggtcattatt cccgcagtgc
    53881 ttgcaatcaa agctcgcaag aagtttccca atcagatgtt cacggtctgg ggcggcaatc
    53941 ttattccggc gattgtcatt ctctttggta taaccgtgat tttgtgctgg ttcggcaacg
    54001 tctttaacgt gttacctaaa tttggctaaa tccttcaaga agccagccat tcgctggctt
    54061 cttgcctctc aggaaatcac ttatgtccaa atggcaactc gcctgatcct ccttcaccac
    54121 gtatgctttg cgtcacctta ctatcaggac gctttagccc atgtcccgct ttttgatttg
    54181 tagttttgcc ctggttttac tttatcccgc cgggattgat atgtacctcg ttggtttacc
    54241 gcgcatcgcc gccgatctca atgccagcga agcgcagttg catattgcgt tctccgtata
    54301 tctggcgggg atggcagctg cgatgttatt tgccggtaaa gtggccgatc gttcagggag
    54361 aaagccggtc gccatacccg gcgcggcgct atttattatt gcctcggtgt tctgttcact
    54421 ggctgaaacc agcacgttat ttcttgcagg ccgatttcta caggggttgg gcgcaggctg
    54481 ttgttacgta gtggcgttcg ctattttgcg cgacacgctg gatgatcgac gtcgggctaa
    54541 agtgctgtca ttactcaacg gtattacctg catcattccg gtgttagcgc cagtgctcgg
    54601 acatctgatt atgcttaaat tcccgtggca gagtctgttc tgggcgatgg caatgatggg
    54661 catcgcggta ctgatgttgt ctttgtttat tttaaaagaa acgcgcccag cggcccccgc
    54721 agcttcggat aaaccacgag aaaatagcga gtcgctgctt aaccgttttt tcctcagccg
    54781 tgttgttatc accaccctca gcgtttcggt gatcctcact ttcgtcaaca cgtcaccggt
    54841 attgctgatg gaaatcatgg ggtttgagcg cggtgaatac gccaccatta tggcgctgac
    54901 cgctggcgtc agcatgaccg tttcattctc cacgccattt gcgctgggaa tttttaagcc
    54961 acgtacgttg atgatcacct cgcaggtgtt attcctggcg gcggggatca ctcttgccgt
    55021 ttcaccttcc catgcggttt ctctgtttgg tatcacgctg atttgcgccg gtttctcggt
    55081 aggttttggt gtggcgatga gtcaggcgtt agggccgttt tcattacgcg cgggcgtagc
    55141 cagctcgacc ttaggtattg cgcaggtttg cggttcgtca ctgtggattt ggctggcagc
    55201 ggtggttggt atcggcgcat ggaatatgct gatcgggatt ctgattgcct gtagcatagt
    55261 gagcctgttg ctgattatgt tcgtcgcgcc tggacgcccc gttgccgctc atgaagaaat
    55321 ccatcaccac gcttgatctc aatctgctgc tttgtctgca actgctgatg caggagcgca
    55381 gcgtaaccaa agcggcgaag cggataaacg tgacaccttc ggcggtgagt aagtcgctgg
    55441 caaagttaag agcgtggttt gacgacccgc tctttgtgaa ctcaccgctg ggtctgtcgc
    55501 ccacaccgct gatggtcagc atggagcaaa atctggcgga gtggatgcaa atgagcaacc
    55561 tgctgctgga taaaccgcac caccagacac cgcgcggcct gaagtttgag ctggcggcgg
    55621 aatcaccgct gatgatgatc atgcttaatg cgctgtcgaa acagatctac caacgttacc
    55681 cgcaggcgac catcaaatta cgtaactggg attacgattc cttagatgcc attactcgtg
    55741 gtgaagtgga tatcggtttt tccggtcgcg aaagccatcc tcgctcgcgg gagctgttaa
    55801 gctcgctacc gttagccatt gattatgaag tgctgtttag tgatgtgccc tgcgtctggt
    55861 tacgcaaaga tcatccggca ctgcatcaaa cgtggaatct ggacaccttc ttacgttatc
    55921 cgcatatcag catttgctgg gaacagagcg atacctgggc gctggacaat gtgttacagg
    55981 agctgggacg cgaacgcacg attgctatga gcctgccgga attcgagcag tcactgttta
    56041 tggcagcgca acccgacaat ctgctactgg cgaccgcgcc gcgctactgt cagtactaca
    56101 atcaactcca tcaactgccg ttggttgctc ttcctctccc gtttgacgaa agccagcaaa
    56161 aaaagctgga agttcctttt accctgctgt ggcataaacg gaacagccat aatccgaaga
    56221 tcgtctggtt acgggaaacc attaaaaacc tttacgcgtc gatggcataa ccgaatcgta
    56281 tgaaacgcga cccaatttca caataaaatg taaaaaagtt gtaataagct tgtctgaatc
    56341 gaacttttag ccgctttagt ctgtccatca ttccagtaaa tgattactct tgtattcata
    56401 atggaccatt aagcatggag cgaaaaatgg cgactcactt tgcccgaggg attttaacgg
    56461 aaggacatct gatttctgtt cgtctcccct cccagtgtca tcaagaagcc cgaaacattc
    56521 cccctcatcg tcaaagccgt tttctggcgt ccagaggttt actcgcagaa ctgatgttca
    56581 tgctgtatgg cattggcgaa ttgccggaaa tcgtcaccct gccgaaaggt aaaccggttt
    56641 tcagtgataa aaatttgcct tcgttttcca tttcctatgc cgggaatatg gttggcgtgg
    56701 cgttaacaac cgaaggtgaa tgtggcctcg atatggaact acagcgtgcg acgcgcgggt
    56761 ttcatagccc acacgcgccc gataaccaca ccttttccag caatgaatcg ctatggatca
    56821 gtaaacaaaa cgatcctaac gaagcgcggg cgcagctcat cacgctgcgc cgaagcgtgc
    56881 taaaactaac cggtgatgtt ttgaatgacg atccgcgcga tctgcagctg ctgcccattg
    56941 ccggacgcct gaaatgtgct catgtaaatc atgtagaagc gttatgcgac gcggaagacg
    57001 tgctggtgtg gtccgtggcg gtcacgccca cgattgaaaa gctcagtgtc tgggagttcg
    57061 atggcaaaca cggctggaaa agcctgccgg atattcacag ccgcgccaac aatcctacca
    57121 gccggatgat gcgttttgcc cagctctcta ccgtgaaggc tttttcgcca aattgataga
    57181 caaccacagg agtcatcatg tctgaaaaat tgcaggtggt tacgttactg gggagcctgc
    57241 gcaaaggctc atttaatggc atggttgcac gtaccctgcc gaaaattgct ccggcgagca
    57301 tggaagtcaa tgcgttacct tccattgccg acattccctt gtatgacgct gacgtacagc
    57361 aggaagaagg ttttccagca acggttgaag ctctggcgga acagatccgt caggctgacg
    57421 gtgtggtgat cgtcacgccg gaatataact actcggtacc gggtgggctg aaaaatgcca
    57481 tcgactggct ttcccgcctg ccggatcaac cgctggccgg taaaccggtg ttgattcaga
    57541 ccagctcaat gggcgtgatt ggcggcgcgc gctgtcagta tcacctgcgc cagattctgg
    57601 ttttcctcga tgcaatggtg atgaacaagc cggaatttat gggcggcgtg attcagaaca
    57661 aagttgatcc gcaaaccgga gaagtgattg atcagggtac gctggaccac ctgaccgggc
    57721 aattgaccgc atttggtgag tttattcagc gagttaagat ctaaataaaa aacccgccag
    57781 caatcatgca tggcgggttt ttaacgcgct atcgatttta gtgagcgtcg ataaagacaa
    57841 tcttcaggat aaacagcagc gcaacgatga ttacgcacgg gcttagatca cgcagacgtc
    57901 cggtaccgat tttcatcacg cagtaggaga taaagcccag cgcgatacct tcggtaatcg
    57961 agaagctgaa cggcatcatc acggcggtaa taaacgccgg aacagattca gtaagatcct
    58021 gccagttcac gcgtgccaga ctggaagtca tcagcacgcc aacgtaaatc agcgcaccag
    58081 ctgcagcgta gcctggcacc atccccgcca gcggcgacag aaagataacc agcaggaaca
    58141 gcagaccaac aaccactgcc gtcagaccgg tacgaccgcc aaccgatacg ccggaagagg
    58201 actcaatata agccgtaacg gaagaagtac cgataaacga accggtcacg gaagagatac
    58261 tgtcgacata cagcgcctgc ttcatgcgcg ggaatttccc cttctcatcc gccagacctg
    58321 ctttatcggt cacgccaatc agcgtaccgg aggagtcaaa caagttgacc aacatgaaag
    58381 agaaaatcac ccctgccagc ccgaggttaa acgacccggc taaatctaca tgacccacaa
    58441 ctgtcattac gctcggcggc gcagaaacga tgccattgta gtgcacatca cccagcatcc
    58501 agcccagcag cgtcgtcacc acgatagaaa ccagcaccgc tgcgtgaatg ttgcgcgagg
    58561 ccagaatagc aatgatgaag aagccgagga tacccagaag tacgctgtga gaagtcagat
    58621 taccgatgct caccagcgtt tccgggttag cgacaatcac acctgcgttt ttcagcccca
    58681 tcatgccaat gaacagaccg ataccgctgg taatacccac acgcagactc accggaatgt
    58741 tggctatcat ccagtagcga acgcggaaaa tcgtcagtaa cagcagacct atcgcgcccc
    58801 agaagattgc gcccatcccg acctgccacg gcaagcccat cgcctgtaca acgacaaaag
    58861 cgaagaacgc attcaggccc atagcgggtg ccagtgcaac tggcaggtta gcaaacagtc
    58921 ccatcataat actgccgaat gcagcgatca gacaggtagt gacgaagacg gcgctggtat
    58981 ccatgccagc aacgccaaga atttgcgggt taacaaaaac gatgtaaacc atcgtcagga
    59041 aggtggtaaa accggcgatc acttcggtcc gtgccgtcgt gccatgttcg cgcagtttaa
    59101 acacgcgttc cagcatcccc tgaccagaag tctgggtggt atgttgatga ctcattatct
    59161 atttccgaac aaggagggaa aatccgtcgc tatcgtatac caaaatgcga caataggcgc
    59221 gtttgtgaga gactttttta ttggatttac ttatacggca acgattgcgt tgcgcaaatc
    59281 ggctctacga aaacgttaaa ctgattaaaa aggaaaggca tgtcccggat agaagcggta
    59341 tttttcgact gcgacggtac gctggtcgac agtgaagtca tttgctctcg cgcatatgta
    59401 acgatgtttc aggaatttgg tattacgctc gatcctgaag aggtattcaa acgtttcaaa
    59461 ggtgtaaaac tgtacgaaat tatcgatatt gtttcccttg aacatggtgt tacgttagcg
    59521 aaaacagaag ctgaacacgt ttaccgtgca gaagtcgctc ggctgttcga ttcagaactg
    59581 gaagccatcg aaggggctgg agcgctcctg tcagcgatca ctgcgccaat gtgtgtggta
    59641 tctaacggcc caaataacaa aatgcagcat tctatgggca agctgaatat gttgcactac
    59701 ttcccggata aactgttcag cggctacgat attcagcgct ggaagccaga cccggcgtta
    59761 atgttccatg cggcaaaagc gatgaatgta aatgtagaaa actgcattct ggttgatgac
    59821 tcagttgccg gtgcacaatc tggtatcgac gcaggtatgg aagtgttcta cttctgcgcc
    59881 gacccgcaca ataagccgat cgttcacccg aaagtcacca cctttaccca tctttcgcag
    59941 ttacctgaac tgtggaaagc gcgtggttgg gatattacgg catagttctt cacactccct
    60001 tcacttaccc cgcttaaatt ggcgctcaaa ggtaagtaaa gggagtttga tatgtctgtt
    60061 tcacgtcggg taatacatca cggactttat tttgcagttt taggaccgtt aattggtgtt
    60121 ctgtttcttg tcctctacat attcttcgca aaagaaccgc tggttctttg ggtgataata
    60181 catccaattt ttctcttatt gtcgataact acgggagcta ttcctgcgtt gttaaccggt
    60241 gtaatggttg cctgtctgcc ggaaaagatc gggtcacaga aacgttatcg ttgtctggct
    60301 ggtggcatag gtggcgtcgt tatcaccgag atctattgtg cagttattgt acatattaag
    60361 ggcatggctt cctcggagtt gtttgaaaac attctttctg gtgacagtct cgttgtccgc
    60421 atcattcctg cattgctggc aggtgtggtg atgagcagaa tcattacccg tctacccgga
    60481 ttggatattt catgtcctga aacagactct ttaagttaag cgggatactt tatctttggg
    60541 ctactcaaaa gcagacagga tgtttctatg actcaaaata tcaggccgtt accccaattc
    60601 aaatatcatc ccaagccact ggaaacaggc gcatttgaac aggataaaac cgtagagtgc
    60661 gattgctgtg aacaacagac gtcagtttat tactcgggtc ccttttattg cgttgatgaa
    60721 gttgaacatc tctgtccgtg gtgtattgcg gacggttctg ctgctgaaaa gtttgcaggt
    60781 agttttcagg atgatgccag catagaaggt gttgaatttg agtatgat
//
LOCUS       DAPOAV010000017        60561 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.017, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000017 DAPOAV010000000
VERSION     DAPOAV010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 60561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60561
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.017"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            315..1979
                     /gene="asnB"
                     /locus_tag="RN951_001290"
     CDS             315..1979
                     /gene="asnB"
                     /locus_tag="RN951_001290"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001724523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase B"
                     /protein_id="HDX2526319.1"
                     /translation="MCSIFGVFDIKTDAVELRKKALELSRLMRHRGPDWSGIYASDNA
                     ILAHERLSIVDVNAGAQPLYNQQKTHVLAVNGEIYNHQALRAEYGDRYQFQTGSDCEV
                     ILALYQEKGPEFLDDLQGMFAFALYDSEKDAYLIGRDHLGIIPLYMGYDEHGQLYVAS
                     EMKALVPVCRTIKEFPAGSYLWSQDGEIRSYYHRDWFDYDAVKDNVTDKNELRQALED
                     SVKSHLMSDVPYGVLLSGGLDSSIISAITKKYAARRVEDQERSEAWWPQLHSFAVGLP
                     GSPDLKAAQEVANHLGTVHHEIHFTVQEGLDAIRDVIYHIETYDVTTIRASTPMYLMS
                     RKIKAMGIKMVLSGEGSDEVFGGYLYFHKAPNAKELHEETVRKLLALHMYDCARANKA
                     MSAWGVEARVPFLDKKFLDVAMRINPQDKMCGNGKMEKHILRECFEAYLPASVAWRQK
                     EQFSDGVGYSWIDTLKEVAAQQVSDQQLETARFRFPYNTPTSKEAYLYREIFEELFPL
                     PSAAECVPGGPSVACSSAKAIEWDEAFKKMDDPSGRAVGVHQSAYK"
     gene            2359..2435
                     /locus_tag="RN951_001291"
     tRNA            2359..2435
                     /locus_tag="RN951_001291"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2393..2395,aa:Met,seq:cat)
     gene            2445..2529
                     /locus_tag="RN951_001292"
     tRNA            2445..2529
                     /locus_tag="RN951_001292"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2479..2481,aa:Leu,seq:tag)
     gene            2553..2627
                     /locus_tag="RN951_001293"
     tRNA            2553..2627
                     /locus_tag="RN951_001293"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2585..2587,aa:Gln,seq:ttg)
     gene            2662..2736
                     /locus_tag="RN951_001294"
     tRNA            2662..2736
                     /locus_tag="RN951_001294"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2694..2696,aa:Gln,seq:ttg)
     gene            2752..2828
                     /locus_tag="RN951_001295"
     tRNA            2752..2828
                     /locus_tag="RN951_001295"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2786..2788,aa:Met,seq:cat)
     gene            2876..2950
                     /locus_tag="RN951_001296"
     tRNA            2876..2950
                     /locus_tag="RN951_001296"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2908..2910,aa:Gln,seq:ctg)
     gene            2988..3062
                     /locus_tag="RN951_001297"
     tRNA            2988..3062
                     /locus_tag="RN951_001297"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3020..3022,aa:Gln,seq:ctg)
     gene            complement(3216..4391)
                     /gene="ubiF"
                     /locus_tag="RN951_001298"
     CDS             complement(3216..4391)
                     /gene="ubiF"
                     /locus_tag="RN951_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol
                     hydroxylase"
                     /protein_id="HDX2526320.1"
                     /translation="MTNQPTEIAIVGGGMVGGALALGLAQHGFAVTVIEHAEPAPFVA
                     DSQPDVRISAISAASVSLLKGLGVWDAVQAMRCHPYRRLETWEWETAHVVFDAAELKL
                     PLLGYMVENTVLQQALWQALEAHPKVTLRVPGSLIALHRHDDLQELELKGGEVIRAKL
                     VIGADGANSQVRQMAGIGVHAWQYAQSCMLISVQCENDPGDSTWQQFTPDGPRAFLPL
                     FDNWASLVWYDSPARIRQLQNMNMAQLQAEIAKHFPSRLGYVTPLAAGAFPLTRRHAL
                     QYVQPGLALVGDAAHTIHPLAGQGVNLGYRDVDALIDVLVNARSYGEAWASYPVLKRY
                     QMRRMADNFIMQSGMDLFYAGFSNNLPPLRFMRNLGLMAAERAGVLKRQALKYALGL"
     gene            4537..5961
                     /gene="miaB"
                     /locus_tag="RN951_001299"
     CDS             4537..5961
                     /gene="miaB"
                     /locus_tag="RN951_001299"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HDX2526321.1"
                     /translation="MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVL
                     LLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDII
                     FGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKY
                     CTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSF
                     ADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNL
                     MGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTEDFEKTMKLIADVNFDMSY
                     SFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGT
                     SRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRV
                     AETPESVIARTRKENDLGVGYYQP"
     gene            6114..7154
                     /locus_tag="RN951_001300"
     CDS             6114..7154
                     /locus_tag="RN951_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415193.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HDX2526322.1"
                     /translation="MNIDTREITLEPADNARLLSLCGPFDDNIKQLERRLGIEINRRD
                     NHFKLTGRPICVTAAADILRSLYVDTAPMRGQIQDIEPEQIHLAIKEARVLEQSAESV
                     PEYGKAVNIKTKRGVIKPRTPNQAQYIANILDHDITFGVGPAGTGKTYLAVAAAVDAL
                     ERQEIRRILLTRPAVEAGEKLGFLPGDLSQKVDPYLRPLYDALFEMLGFEKVEKLIER
                     NVIEVAPLAYMRGRTLNDAFIILDESQNTTIEQMKMFLTRIGFNSKAVITGDVTQIDL
                     PRNTKSGLRHAIEVLADVEEISFNFFHSEDVVRHPVVARIVNAYEAWEEAEQKRKAAL
                     AAERKREEQEQK"
     gene            7151..7618
                     /gene="ybeY"
                     /locus_tag="RN951_001301"
     CDS             7151..7618
                     /gene="ybeY"
                     /locus_tag="RN951_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014169133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HDX2526323.1"
                     /translation="MSQVILDLQLACEDNSGLPEESQFQTWLNAVIPQFQEESEVTIR
                     VVDTAESHSLNLTYRGKDKPTNVLSFPFEVPPGMEMSLLGDLVICRQVVEKEAQEQGK
                     PLEAHWAHMVVHGSLHLLGYDHIEDDEAEEMEALETEIMLALGYEDPYIAEKE"
     gene            7708..8586
                     /gene="corC"
                     /locus_tag="RN951_001302"
     CDS             7708..8586
                     /gene="corC"
                     /locus_tag="RN951_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308723.1"
                     /note="CorC(YbeX) belongs to the Cyclin M Mg2+ Exporter
                     (CNNM) family, and was characterized as belonging to a set
                     of three proteins, at least one of which must be present
                     for CorA to function; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family magnesium/cobalt transport protein
                     CorC"
                     /protein_id="HDX2526324.1"
                     /translation="MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDS
                     GQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSR
                     FPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRS
                     QRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALA
                     SIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQ
                     VHVKIPDDSPQPKLDE"
     gene            8611..10149
                     /gene="lnt"
                     /locus_tag="RN951_001303"
     CDS             8611..10149
                     /gene="lnt"
                     /locus_tag="RN951_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="apolipoprotein N-acyltransferase"
                     /protein_id="HDX2526325.1"
                     /translation="MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIISLMGL
                     QALTFNRRPLQSAAIGFCWGFGLFGSGINWVYVSIATFGGMPGPVNIFLVVLLAAYLS
                     LYTGLFAGVLSRLWPKTTWLRVAIAAPALWQVTEFLRGWVLTGFPWLQFGYSQIDGPL
                     KGLAPIMGVEAINFLLMMVSGLLALALVKRNWRPLVVAVVLFALPFPLRYIQWFTPQP
                     EKTIQVSMVQGDIPQSLKWDEGQLLNTLKIYYNATAPLMGKSSLIIWPESAITDLEIN
                     QQPFLKALDGELRDKGSSLVTGIVDARLNKQNRYDTYNTIITLGKGAPYSYESADRYN
                     KNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPPLSANGIELTAAICYEIIL
                     GEQVRDNFRPDTDYLLTISNDAWFGKSIGPWQHFQMARMRALELARPLLRSTNNGITA
                     VIGPQGEIQAMIPQFTREVLTTNVTPTTGLTPYARTGNWPLWVLTALFGFAAVLMSLR
                     QRRK"
     gene            10546..11454
                     /gene="gltI"
                     /locus_tag="RN951_001304"
     CDS             10546..11454
                     /gene="gltI"
                     /locus_tag="RN951_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter
                     substrate-binding protein GltI"
                     /protein_id="HDX2526326.1"
                     /translation="MQLRKPATAILALALSAGLAQADDAAPAAGSTLDKIAKNGVIVV
                     GHRESSVPFSYYDNQQKVVGYSQDYSNAIVEAVKKKLNKPDLQVKLIPITSQNRIPLL
                     QNGTFDFECGSTTNNVERQKQAAFSDTIFVVGTRLLTKKGGDIKDFANLKDKAVVVTS
                     GTTSEVLLNKLNEEQKMNMRIISAKDHGDSFRTLESGRAVAFMMDDALLAGERAKAKK
                     PDNWEIVGKPQSQEAYGCMLRKDDPQFKKLMDDTIAQVQTSGEAEKWFDKWFKNPIPP
                     KNLNMNFELSDEMKALFKEPNDKALN"
     gene            11624..12364
                     /gene="gltJ"
                     /locus_tag="RN951_001305"
     CDS             11624..12364
                     /gene="gltJ"
                     /locus_tag="RN951_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltJ"
                     /protein_id="HDX2526327.1"
                     /translation="MSIDWNWGIFLQQAPFGNTTYLGWIWSGFQVTIALSICAWIIAF
                     LVGSFFGILRTVPNRFLSGLGTLYVELFRNVPLIVQFFTWYLVIPELLPEKIGMWFKA
                     ELDPNIQFFLSSMLCLGLFTAARVCEQVRAAIQSLPRGQKNAALAMGLTLPQAYRYVL
                     LPNAYRVIVPPMTSEMMNLVKNSAIASTIGLVDMAAQAGKLLDYSAHAWESFTAITLA
                     YVLINAFIMLVMTLVERKVRLPGNMGGK"
     gene            12364..13038
                     /gene="gltK"
                     /locus_tag="RN951_001306"
     CDS             12364..13038
                     /gene="gltK"
                     /locus_tag="RN951_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltK"
                     /protein_id="HDX2526328.1"
                     /translation="MYEFDWSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTMLAVM
                     RLSSFAPVAWFAKAYVNVFRSIPLVMVLLWFYLIVPGFLQNVLGLSPKNDIRLISAMV
                     AFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLT
                     QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLSASLLVSY
                     LKRRTA"
     gene            13038..13763
                     /gene="gltL"
                     /locus_tag="RN951_001307"
     CDS             13038..13763
                     /gene="gltL"
                     /locus_tag="RN951_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter ATP binding
                     protein GltL"
                     /protein_id="HDX2526329.1"
                     /translation="MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLI
                     KTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAQ
                     VKVLKRDKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF
                     DEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIVEDS
                     PKDAFFDDPKSDRAKDFLAKILH"
     gene            13881..14816
                     /gene="rihA"
                     /locus_tag="RN951_001308"
     CDS             13881..14816
                     /gene="rihA"
                     /locus_tag="RN951_001308"
                     /EC_number="3.2.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-specific ribonucleoside hydrolase
                     RihA"
                     /protein_id="HDX2526330.1"
                     /translation="MALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEK
                     TLRNVLRMLTLLNRTDIPVAGGAVKPLMRELIIADNVHGESGLDGPALPEPTFAPQNC
                     TAVELMAKTLRESAEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWT
                     PAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHVEDTERFRAIGNPVSTIVAE
                     LLDFFLEYHKDEKWGFVGAPLHDPCTIAWLLKPELFTSVERWVGVETQGKYTQGMTVV
                     DYYYLTGNKPNATVMVDVDRQGFVDLLADRLKFYA"
     gene            14900..16570
                     /gene="hscC"
                     /locus_tag="RN951_001309"
     CDS             14900..16570
                     /gene="hscC"
                     /locus_tag="RN951_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HscC"
                     /protein_id="HDX2526331.1"
                     /translation="MDNAELAIGIDLGTTNSLIAVWKDGAAQLIPNKFGEYLTPSIIS
                     MDENNHILVGKPAVSRRTSHPDKTAALFKRAMGSNTNWRLGSDTFNAPELSSLVLRSL
                     KEDAEEFLQRPIKDVVISVPAYFSDEQRKHTRLAAELAGLNAVRLINEPTAAAMAYGL
                     HTQQNTRSLVFDLGGGTFDVTVLEYATPVIEVHASAGDNFLGGEDFTHMLVDEVLKRA
                     DVARTTLNESELAALYACVEAAKCSNQSPLHIRWQYQEETRECEFYENELEDLWLPLL
                     NRLRVPIEQALRDARLKPSQIDSLVLVGGASQMPLVQRIAVRLFGKLPYQSYDPSTIV
                     ALGAAIQAACRLRSEDIEEVILTDICPYSLGVEVNRQGVSGIFSPIIERNTTVPVSRV
                     ETYSTMHPEQDSITVNVYQGENHKVKNNILVESFDVPLKKTGAYQSIDIRFSYDINGL
                     LEVDVLLEDGSVKSRVINHSPVTLSAQQIEESRTRLSALKIYPRDMLINRTFKAKLEE
                     LWARALGDEREEIGRVITDFDAALQSNDMARVDEVRRRASDYLAIEIP"
     gene            complement(16630..18081)
                     /gene="djlC"
                     /locus_tag="RN951_001310"
     CDS             complement(16630..18081)
                     /gene="djlC"
                     /locus_tag="RN951_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone DjlC"
                     /protein_id="HDX2526332.1"
                     /translation="MKTCWQILEIESTTQIDIIRQAYLARLPLCHPETDPQGFKALRQ
                     AYEEALRLAVNPVEEADDEEKDAAAEHEILRAFRTLLDSESDRFQPSAWQKFIQQLNT
                     WNMEDVDQLRWPLCAIAIEARYLSLNCASLLAERLNWHSFNDSEGMDEEEREAFLEAI
                     QAGDCFDFLSLLEYPIALQNQTVEYYFALERCCRYHPDYVTAFLAMEGPWLIPDDAKL
                     HRKLLRWYSSVQTGMAELIPVAQQWQTEEPESEDARYYLCAQRLYCGEGESLLADLCA
                     YWESYPSTQADNLLLQWSKRHCPDYFALLVMVIEARSMVDAQGQPLKYVPGESARTRL
                     LWAEILHSGKLSPLGQSFIESLFFKRKAWAWWKSRVGSETEQDSPFLDLYRVAEQVVL
                     EAFPKQEMLARLNTRLEGGDAHPLEAIVTRMLLTKVKLEPEDEDVDEPTPENHEEKND
                     EGEKPQSITSIIKISLTVLVIGYALGKIAMLFS"
     gene            complement(18078..18785)
                     /locus_tag="RN951_001311"
     CDS             complement(18078..18785)
                     /locus_tag="RN951_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HDX2526333.1"
                     /translation="MNKEEQYLLFALSAPMEILNQGCKPAHDSPKMYTGIKEFELSSS
                     WGINNRDDLIQTIYQMTDDGHANDLAGLYLTWHRSSPEEWKALIAGGSERGLIYTQFV
                     AQTAMCCGEGGIKAWDYVRMGFLSRVGVLNKWLTEEESLWLQSRVYVRAHHYYHSWMH
                     YFSAYSLGRLYWQSSQCEDNTSLREALTLYKYDSAGSRMFEELAAGSDRFYATLPWQP
                     LTVQSECPVTLKDVSDL"
     gene            18887..19441
                     /locus_tag="RN951_001312"
     CDS             18887..19441
                     /locus_tag="RN951_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDX2526334.1"
                     /translation="MNKKLMYIFAIFIVAAITCISQPKKTTLRDKAMVNYAFDYLSSP
                     GSLPFTTAATELSAIHGHSTSQYRLGEFYLHGSDGKPLDYTQARYWYEQSAEQENPRA
                     QSKLGWIYLKGLGVKPDTRKAILWYKEAAEQGYAHAQYTLGLIYRNGSGINVNHYESQ
                     KWLKLAAKQHYKNAERLLAGLPAH"
     gene            complement(19451..20878)
                     /locus_tag="RN951_001313"
     CDS             complement(19451..20878)
                     /locus_tag="RN951_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="HDX2526335.1"
                     /translation="MKNCWKILDIEETTDVDIIRRAYLALLPSFHPETDPQGFKQLRQ
                     AYEEALRIAQSPAKSVWQPEEYEVAEHEILLAFRALLASDSERFLPSAWQRFIQQLNY
                     CSMEEIDELRWSLCTIAMNTAHLSFECVVLLAERLRWLQEENTGEIDEEELESFLYAI
                     AKGNVFNFQTILHLPVAVQNDTIDFYQMFARIWSSHPQWLTLYLAQHRAVIIPDDAKL
                     HRNLLRWYSAGRLDIPELLDYAQSWRETEPDNEDAPYYEYAQRVYCGEGESLLAELCD
                     YWREYPSTQADALMLQWCRQHRVDYYPLLVMMIEARDLVNDQGKPLLYVPGDSARTRF
                     HLYEILSDEKLSALGRSLVEMVLHKGRKPRISLTRDTEHTLWPLYLVAKQLVQACQPT
                     EESLMPIVSRLDAENRCPLEALIIRRLLIQAANFTEKQTVEPEPQPQPMPVDDGGPGC
                     LGIIKIIFYIFIFAGLIGKILHLFG"
     gene            complement(20875..21582)
                     /locus_tag="RN951_001314"
     CDS             complement(20875..21582)
                     /locus_tag="RN951_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HDX2526336.1"
                     /translation="MDMESQKILFALSTPMEIRNECCLPSHSSPKMYLGTCFFDLSSS
                     WGIDDRDDLLRTIHRMIDNGHAARLAGFYHRWFRYSPCEWRDYLAELNEQGQAYAQFV
                     ASTAECCGEGGIKAWDYVRMGFLSRMGVLNNWLSEEESLWIQSRIHLRALRYYSNWRQ
                     YFAGYTFGRQYWQSPEDDHLPLLREFLARKEYDDSGNDMFYQLFASDDAYYPTLSWQP
                     LAYYSACPETLKDMSDL"
     gene            21746..22723
                     /locus_tag="RN951_001315"
     CDS             21746..22723
                     /locus_tag="RN951_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415177.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEL1-like repeat protein"
                     /protein_id="HDX2526337.1"
                     /translation="MIFTSSCCDNLSIDEIIERAEKGDCEAQYIVGFYYNRDSAIDSP
                     DDEKAFYWLKLAAEQGHCEAQYSLGQKYTEDKSRHKDNEQAIFWLKKAALQGHTFASN
                     ALGWTLDRGEAPNYKEAVVWYQIAAESGMSYAQNNLGWMYRNGNGVAKDYALAFFWYK
                     QAALQGHSDAQNNLADLYEDGKGVAQNKTLAAFWYLKSAQQGNRHAQFQIAWDYNAGE
                     GVDQDYKQAMYWYLKAAAQGSVGAYVNIGYMYKHGQGVEKDYQAAFEWFTKAAECNDA
                     TAWYNLAIMYHYGEGRPVDLRQALDLYRKVQSSGTRDVSQEIRETEDLL"
     gene            complement(22793..23275)
                     /locus_tag="RN951_001316"
     CDS             complement(22793..23275)
                     /locus_tag="RN951_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon-containing protein"
                     /protein_id="HDX2526338.1"
                     /translation="MNKVAQYYRELVASLSERLRNGERDIDALVEQARERVIKTGELT
                     RTEVDELTRAVRRDLEEFAMSYEESLKEESDSVFMRVIKESLWQELADITDKTQLEWR
                     EVFQDLNHHGVYHSGEVVGLGNLVCEKCHFHLPIYTPEVLTLCPKCGHDQFQRRPFEP
                     "
     gene            23510..26092
                     /gene="leuS"
                     /locus_tag="RN951_001317"
     CDS             23510..26092
                     /gene="leuS"
                     /locus_tag="RN951_001317"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008456064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HDX2526339.1"
                     /translation="MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYP
                     SGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTY
                     DNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP
                     NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKT
                     MQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNP
                     ELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGA
                     VMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDH
                     EAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQL
                     PVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQY
                     KEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQ
                     GMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSK
                     NNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTA
                     KGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAP
                     TDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVED
                     STLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLN
                     LVVG"
     gene            26107..26688
                     /gene="lptE"
                     /locus_tag="RN951_001318"
     CDS             26107..26688
                     /gene="lptE"
                     /locus_tag="RN951_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly lipoprotein LptE"
                     /protein_id="HDX2526340.1"
                     /translation="MRYLATLLLSLAVLITAGCGWHLRDTTQVPSTMKVMILDSGDPN
                     GPLSRAVRNQLRLNGVELLDKETTRKDVPSLRLGKVSIAKDTASVFRNGQTAEYQMIM
                     TVNATVLIPGRDIYPISAKVFRSFFDNPQMALAKDNEQDMIVKEMYDRAAEQLIRKLP
                     SIRAADIRSDEEQTSTTTDTPATPARVSTTLGN"
     gene            26688..27719
                     /gene="holA"
                     /locus_tag="RN951_001319"
     CDS             26688..27719
                     /gene="holA"
                     /locus_tag="RN951_001319"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HDX2526341.1"
                     /translation="MIRLYPEQLRAQLNEGLRAAYLLLGNDPLLLQESQDAVRQVAAA
                     QGFEEHHTFSIDPNTDWNAIFSLCQAMSLFASRQTLLLLLPENGPNAAINEQLLTLTG
                     LLHDDLLLIVRGNKLSKAQENAAWFTALANRSVQVTCQTPEQAQLPRWVAARAKQLNL
                     ELDDAANQVLCYCYEGNLLALAQALERLSLLWPDGKLTLPRVEQAVNDAAHFTPFHWV
                     DALLMGKSKRALHILQQLRLEGSEPVILLRTLQRELLLLVNLKRQSAHTPLRALFDKH
                     RVWQNRRGMMGEALNRLSQTQLRQAVQLLTRTELTLKQDYGQSVWAELEGLSLLLCHK
                     PLADVFIDG"
     gene            27721..28362
                     /gene="nadD"
                     /locus_tag="RN951_001320"
     CDS             27721..28362
                     /gene="nadD"
                     /locus_tag="RN951_001320"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HDX2526342.1"
                     /translation="MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPP
                     HRPQPEANSVQRKHMLELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDVPL
                     AFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHNPED
                     LHLQPAGKIYLAETPWFNISATIIRERLQNGESCEDLLPEPVLTYINQQGLYR"
     gene            28386..28997
                     /locus_tag="RN951_001321"
     CDS             28386..28997
                     /locus_tag="RN951_001321"
                     /EC_number="3.1.3.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin/alpha-ribazole phosphatase"
                     /protein_id="HDX2526343.1"
                     /translation="MRLWLIRHGETQANIDGLYSGHAPTPLTARGIEQAQNLHTLLHG
                     VSFDLVLCSELERAQHTARLVLSDRQLPVQIIPELNEMFFGDWEMRHHRDLMQEDAEN
                     YSAWCNDWQHAIPTNGEGFQAFSQRVERFIARLSEFQHYQNILVVSHQGVLSLLIARL
                     IGIPAEAMWHFRVDQGCWSAIDINQKFATLRVLNSRAIGVENA"
     gene            29257..29574
                     /gene="rsfS"
                     /locus_tag="RN951_001322"
                     /gene_synonym="rsfA"
     CDS             29257..29574
                     /gene="rsfS"
                     /locus_tag="RN951_001322"
                     /gene_synonym="rsfA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007373852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HDX2526344.1"
                     /translation="MQGKALQDFVIDKIDDLKGQDIIALDVQGKSSITDCMIICTGTS
                     SRHVMSIADHVVQESRAAGLLPLGVEGENSADWIVVDLGDVIVHVMQEESRRLYELEK
                     LWS"
     gene            29578..30045
                     /gene="rlmH"
                     /locus_tag="RN951_001323"
     CDS             29578..30045
                     /gene="rlmH"
                     /locus_tag="RN951_001323"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HDX2526345.1"
                     /translation="MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRG
                     KNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLAAELERWKLDGRDVSLLI
                     GGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE"
     gene            30076..31977
                     /gene="mrdA"
                     /locus_tag="RN951_001324"
     CDS             30076..31977
                     /gene="mrdA"
                     /locus_tag="RN951_001324"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-transpeptidase MrdA"
                     /protein_id="HDX2526346.1"
                     /translation="MKLQNSFRDYTAESALFVRRALVAFLGILLLTGVLIANLYNLQI
                     VRFTDYQTRSNENRIKLVPIAPSRGIIYDRNGIPLALNRTIYQIEMMPEKVDNVQQTL
                     DALRSVVDLTDDDIAAFRKERARSHRFTSIPVKTNLTEVQVARFAVNQYRFPGVEVKG
                     YKRRYYPYGSALTHVIGYVSKINDKDVERLNNDGKLANYAATHDIGKLGIERYYEDVL
                     HGQTGYEEVEVNNRGRVIRQLKEVPPQAGHDIYLTLDLKLQQYIETLLAGSRAAVVVT
                     DPRTGGVLALVSTPSYDPNLFVDGISSKDYSALLNDPNTPLVNRATQGVYPPASTVKP
                     YVAVSALSAGVITRNTTLFDPGWWQLPGSEKRYRDWKKWGHGRLNVTRSLEESADTFF
                     YQVAYDMGIDRLSEWMGKFGYGHYTGIDLAEERSGNMPTREWKQKRFKKPWYQGDTIP
                     VGIGQGYWTATPIQMSKALMILINDGIVKVPHLLMSTAEDGKQVPWVQPHEPPVGDIH
                     SGYWELAKDGMYGVANRPNGTAHKYFASAPYKIAAKSGTAQVFGLKANETYNAHKIAE
                     RLRDHKLMTAFAPYNNPQVAVAMILENGGAGPAVGTLMRQILDHIMLGDNNTDLPAEN
                     PAVAAAEDH"
     gene            31980..33092
                     /gene="mrdB"
                     /locus_tag="RN951_001325"
                     /gene_synonym="rodA"
     CDS             31980..33092
                     /gene="mrdB"
                     /locus_tag="RN951_001325"
                     /gene_synonym="rodA"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004885876.1"
                     /note="rod shape-determining protein RodA; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase MrdB"
                     /protein_id="HDX2526347.1"
                     /translation="MTDNPNKKTFWDKVHLDPTMLLILLALLVYSALVIWSASGQDIG
                     MMERKIGQIAMGLVIMVVMAQIPPRVYEGWAPYLYIICIILLVAVDAFGAISKGAQRW
                     LDLGIVRFQPSEIAKIAVPLMVARFINRDVCPPSLKNTGIALVLIFMPTLLVAAQPDL
                     GTSILVALSGLFVLFLSGLSWRLIGVAVVLVAAFIPILWFFLMHDYQRQRVMMLLDPE
                     SDPLGAGYHIIQSKIAIGSGGLRGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLVG
                     ILILLALYILLIMRGLWIAARAQTTFGRVMAGGLMLILFVYVFVNIGMVSGILPVVGV
                     PLPLVSYGGSALIVLMAGFGIVMSIHTHRKMLSKSV"
     gene            33103..34191
                     /gene="rlpA"
                     /locus_tag="RN951_001326"
     CDS             33103..34191
                     /gene="rlpA"
                     /locus_tag="RN951_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic peptidoglycan transglycosylase RlpA"
                     /protein_id="HDX2526348.1"
                     /translation="MRKQWLGICIAAGMLAACTSDDGQQQTVSVPQPAVCNGPIVEIS
                     GADPRFEPLNATANQDYQRDGKSYKIVQDPSRFSQAGLAAIYDAEPGSNLTASGEAFD
                     PTQLTAAHPTLPIPSYARITNLANGRMIVVRINDRGPYGNDRVISLSRAAADRLNTSN
                     NTKVRIDPIIVAQDGSLSGPGMACTTVAKQTYALPAPPDLSGGAGTSSVSGPQGDILP
                     VSNSTLKSEDPTGAPVTSSGFLGAPTTLAPGVLEGSEPTPAPQPVVTAPSTTPATSPA
                     MVTPQAVSQSASGNFMVQVGAVSDQARAQQYQQQLGQKFGVPGRVTQNGAVWRIQLGP
                     FASKAEASTLQQRLQTEAQLQSFITTAQ"
     gene            34330..35541
                     /gene="dacA"
                     /locus_tag="RN951_001327"
     CDS             34330..35541
                     /gene="dacA"
                     /locus_tag="RN951_001327"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase DacA"
                     /protein_id="HDX2526349.1"
                     /translation="MNTIFSARIMKRLALTTALCTAFISAAHADDLNIKTMIPGVPQI
                     DAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGN
                     DAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVG
                     LMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFT
                     FNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKG
                     REAESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRM
                     KDLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNFFGKIID
                     YIKLMFHHWFG"
     gene            35651..35914
                     /locus_tag="RN951_001328"
     CDS             35651..35914
                     /locus_tag="RN951_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbeD family protein"
                     /protein_id="HDX2526350.1"
                     /translation="MKTKLNELLEFPTPFTYKVMGQALPELVDQVVEVVQRHAPGDYT
                     PTVKPSSKGNYHSVSITINATHIEQVETLYEELGKIDIVRMVL"
     gene            36015..36656
                     /gene="lipB"
                     /locus_tag="RN951_001329"
     CDS             36015..36656
                     /gene="lipB"
                     /locus_tag="RN951_001329"
                     /EC_number="2.3.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415163.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl(octanoyl) transferase LipB"
                     /protein_id="HDX2526351.1"
                     /translation="MYQDKILVRQLGLQPYEPISQAMHEFTDTRDDSTLDEIWLVEHY
                     PVFTQGQAGKAEHILMPGDIPVIQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRELV
                     TLLEQTVVNTLAELGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDL
                     SPFLRINPCGYAGMEMAKISQWKPEATTNNIAPRLLENILALLNNPDFEYITA"
     gene            36915..37868
                     /locus_tag="RN951_001330"
     CDS             36915..37868
                     /locus_tag="RN951_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415162.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HDX2526352.1"
                     /translation="MDSNNQIEPCLSRKSSEGKPQIFTTLRNIDLNLLTIFEAVYVHK
                     GIVNAAKVLNLTPSAISQSIQKLRVIFPDPLFIRKGQGVTPTAFAMHLHEYISQGLES
                     ILGALDIEGSYDKQRTITIATTPSVGALVLPVIYRAIKTHYPQLLLRNPPISDAENQL
                     SQFQTDLIIDNMFCTNRTVQHHVLFTDNMVLICREGNPLLSLEDDRETIDNAAHVLLL
                     PEEQNFSGLRQRVQEMFPDRQINFTSYNILTIAALVANSDMLAIIPSRFYNLFSRCWP
                     LEKLPFPSLNEEQIDFSIHYNKFSLRDPILHGVIDVIRNAF"
     gene            38077..39042
                     /gene="lipA"
                     /locus_tag="RN951_001331"
     CDS             38077..39042
                     /gene="lipA"
                     /locus_tag="RN951_001331"
                     /EC_number="2.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl synthase"
                     /protein_id="HDX2526353.1"
                     /translation="MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIK
                     LPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCD
                     VAHGRPVAPDANEPVKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIREKS
                     PQIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLL
                     ERFKEAHPEIPTKSGLMVGLGETNEEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQ
                     RYVSPDEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK"
     gene            complement(39143..39346)
                     /gene="tatE"
                     /locus_tag="RN951_001332"
     CDS             complement(39143..39346)
                     /gene="tatE"
                     /locus_tag="RN951_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase subunit TatE"
                     /protein_id="HDX2526354.1"
                     /translation="MGEISITKLLVVAALVVLLFGTKKLRTLGGDLGAAIKGFKKAMN
                     DDDAAAKKGADVDLQAEKLSHKE"
     gene            complement(39475..40262)
                     /locus_tag="RN951_001333"
                     /pseudo
     CDS             complement(39475..40262)
                     /locus_tag="RN951_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308691.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deaminated glutathione amidase"
     gene            40355..40738
                     /gene="crcB"
                     /locus_tag="RN951_001334"
     CDS             40355..40738
                     /gene="crcB"
                     /locus_tag="RN951_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HDX2526355.1"
                     /translation="MLQLLLAVFIGGGTGSVARWLLSMRFNPLHQAIPLGTLTANLIG
                     AFIIGIGFAWFSRMTNIDPVWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLN
                     VFVNLLGSFAMTALAFWLFSASTAH"
     gene            complement(40792..41001)
                     /gene="cspE"
                     /locus_tag="RN951_001335"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             complement(40792..41001)
                     /gene="cspE"
                     /locus_tag="RN951_001335"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HDX2526356.1"
                     /translation="MSKIKGNVKWFNESKGFGFITPEDGSKDVFVHFSAIQTNGFKTL
                     AEGQRVEFEITNGAKGPSAANVIAL"
     gene            complement(41176..41736)
                     /gene="pagP"
                     /locus_tag="RN951_001336"
     CDS             complement(41176..41736)
                     /gene="pagP"
                     /locus_tag="RN951_001336"
                     /EC_number="2.3.1.251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) palmitoyltransferase PagP"
                     /protein_id="HDX2526357.1"
                     /translation="MNVSKYVAIFSFVFIQLISVGKVFANADEWMTTFRENIAQTWQQ
                     PEHYDLYIPAITWHARFAYDKEKTDRYNERPWGGGFGLSRWDEKGNWHGLYAMAFKDS
                     WNKWEPIAGYGWESTWRPLADENFHLGLGFTAGVTARDNWNYIPLPVLLPLASVGYGP
                     VTFQMTYIPGTYNNGNVYFAWMRFQF"
     gene            42325..43710
                     /gene="dcuC"
                     /locus_tag="RN951_001337"
     CDS             42325..43710
                     /gene="dcuC"
                     /locus_tag="RN951_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuC"
                     /protein_id="HDX2526358.1"
                     /translation="MLTFIELLIGVVVIVGVARYIIKGYSATGVLFVGGLLLLIISAI
                     MGHKVLPSSQASTGYSATDIVEYVKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMV
                     VKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRG
                     AAAAICASPAAIILAPTSGDVVLAAQASEMSLIDFAFKTTLPISIAAIIGMAIAHFFW
                     QRYLDKKEHISHEMLDVSEITTTAPAFYAILPFTPIIGVLIFDGKWGPQLHIITILVI
                     CMLIASILEFLRSFNTQKVFSGLEVAYRGMADAFANVVMLLVAAGVFAQGLSTIGFIQ
                     SLISIATSFGSASIILMLVLVILTMLAAVTTGSGNAPFYAFVEMIPKLAHSSGINPAY
                     LTIPMLQASNLGRTLSPVSGVVVAVAGMAKISPFEVVKRTSVPVLVGLVIVIVATELM
                     VPGTAAAVTGK"
     gene            complement(43751..44431)
                     /gene="dpiA"
                     /locus_tag="RN951_001338"
                     /gene_synonym="citB"
     CDS             complement(43751..44431)
                     /gene="dpiA"
                     /locus_tag="RN951_001338"
                     /gene_synonym="citB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component response regulator DpiA"
                     /protein_id="HDX2526359.1"
                     /translation="MTAPLTLLIVEDETPLAEMHAEYIRHIPGFSQILLAGNLAQARM
                     MIERFKPGLILLDNYLPDGRGINLLHELVQAHYPGDVVFTTAASDMETVSEAVRCGVF
                     DYLIKPIAYERLGQTLTRFRQRKHMLESIDSASQKQIDEMFNAYARGEPKDELPTGID
                     PLTLNAVRKLFKEPGVQHTAETVAQALTISRTTARRYLEYCASRHLIIAEIVHGKVGR
                     PQRIYHSG"
     gene            complement(44400..46058)
                     /gene="dpiB"
                     /locus_tag="RN951_001339"
     CDS             complement(44400..46058)
                     /gene="dpiB"
                     /locus_tag="RN951_001339"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase DpiB"
                     /protein_id="HDX2526360.1"
                     /translation="MLQLNENKQFAFFQRLAFPLRIFLLILVFSIFVIAALAQYFTAS
                     FEDYLTLHVRDMAMNQAKIIASNDSVISAVKTRDYKRLATIANKLQRDTDFDYVVIGD
                     RHSIRLYHPNPEKIGYPMQFTKQGALEKGESYFITGKGSMGMAMRAKTPIFDDDGKVI
                     GVVSIGYLVSKIDSWRAEFLLPMAGVFVVLLGILMLLSWFLAAHIRRQMMGMEPKQIA
                     RVVRQQEALFSSVYEGLIAVDPHGYITAINRNARKMLGLSSPGRQWLGKPIVEVVRPA
                     DFFTEQIDEKRQDVVANFNGLSVIANREAIRSGDDLLGAIISFRSKDEISTLNAQLTQ
                     IKQYVESLRTLRHEHLNWMSTLNGLLQMKEYDRVLAMVQGESQAQQQLIDSLREAFAD
                     RQVAGLLFGKVQRARELGLKMIIVPGSQLSQLPPGLDSTEFAAIVGNLLDNAFEASLR
                     SDEGNKIVELFLSDEGDDVVIEVADQGCGVPESLRDKIFEQGVSTRADEPGEHGIGLY
                     LIASYVTRCGGVITLEDNDPCGTLFSIYIPKVKPNDSSINPIDR"
     gene            46437..47495
                     /gene="citC"
                     /locus_tag="RN951_001340"
     CDS             46437..47495
                     /gene="citC"
                     /locus_tag="RN951_001340"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415151.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HDX2526361.1"
                     /translation="MFGNDIFTRVKRSENKKMAEIAQFLHENDLSVDTTVEVFITVTR
                     DEKLIACGGIAGNIIKCVAISESVRGEGLALTLATELINLAYERHSTHLFIYTKTEYE
                     ALFRQCGFSTLTSVPGVMVLMENSATRLKRYAESLKKFRHPGNKIGCIVMNANPFTNG
                     HRYLIQQAAAQCDWLHLFLVKEDSSRFPYEDRLDLVLKGTADIPRLTVHRGSEYIISR
                     ATFPCYFIKEQSVINHCYTEIDLKIFRQYLAPALGVTHRFVGTEPFCRVTAQYNQDMR
                     YWLETPTISAPPIELVEIERLRYQEMPISASRVRQLLAKNDLTAIAPLVPAVTLHYLQ
                     NLLEHSRQDAAARQKTPA"
     gene            47510..47806
                     /gene="citD"
                     /locus_tag="RN951_001341"
     CDS             47510..47806
                     /gene="citD"
                     /locus_tag="RN951_001341"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HDX2526362.1"
                     /translation="MKINQPAVAGTLESGDVMIRIAPLDTQDIDLQINSSVEKQFGDA
                     IRTTILDVLARYNVRGVQLNVDDKGALDCILRARLEALLARASGIPALPWEDCQ"
     gene            47803..48711
                     /gene="citE"
                     /locus_tag="RN951_001342"
     CDS             47803..48711
                     /gene="citE"
                     /locus_tag="RN951_001342"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415149.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HDX2526363.1"
                     /translation="MISASLQQRKTRTRRSMLFVPGANAAMVSNSFIYPADALMFDLE
                     DSVALREKDTARRMVYHALQHPLYRDIETIVRVNALDSEWGVNDLEAVVRGGADVVRL
                     PKTDTAQDVLDIEKEILRIEKACGREPGSTGLLAAIESPLGITRAVEIAHASERLIGI
                     ALGAEDYVRNLRTERSPEGTELLFARCSILQAARSAGIQAFDTVYSDANNEAGFLQEA
                     AHIKQLGFDGKSLINPRQIDLLHNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNG
                     KMVDGPVIDRARLVLSRAELSGIREE"
     gene            48722..50254
                     /gene="citF"
                     /locus_tag="RN951_001343"
     CDS             48722..50254
                     /gene="citF"
                     /locus_tag="RN951_001343"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HDX2526364.1"
                     /translation="MTQKIEQSQRQERVAAWNRRAECDLAAFQNSPKQTYQAEKARDR
                     KLCANLEEAIRRSGLQDGMTVSFHHAFRGGDLTVNMVMDVIAKMGFKNLTLASSSLSD
                     CHAPLVEHIRQGVVTRIYTSGLRGPLAEEISRGLLAEPVQIHSHGGRVHLVQSGELNI
                     DVAFLGVPSCDEFGNANGYTGKACCGSLGYAMVDADNAKQVVMLTEELLPYPHNPASI
                     EQDQVDLIVKVDRVGDAAKIGAGATRMTTNPRELLIARSAADVIVNSGYFKEGFSMQT
                     GTGGASLAVTRFLEDKMRSRDIRADFALGGITATMVDLHEKGLIRKLLDVQSFDSHAA
                     QSLARNPNHIEISANQYANWGSKGASVDRLDVVVLSALEIDTQFNVNVLTGSDGVLRG
                     ASGGHCDTAIASALSIIVAPLVRGRIPTLVDNVLTCITPGSSVDILVTDHGIAVNPAR
                     PELAERLQEAGIKVVSIEWLRERARLLTGEPQPIEFTDRVVAVVRYRDGSVIDVVHQV
                     KE"
     gene            50258..50809
                     /gene="citX"
                     /locus_tag="RN951_001344"
     CDS             50258..50809
                     /gene="citX"
                     /locus_tag="RN951_001344"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HDX2526365.1"
                     /translation="MHLLPELASHHAVSIPELLVSRDERQARQHVWLKRHPVPLVSFT
                     VVAPGPIKDSEVTRRIFNHGVTALRALAAKQGWQIQEQAALVSASGPEGMLSIAAPAR
                     DLKLATIELEHSHPLGRLWDIDVLTPEGEILSRRDYSLPPRRCLLCEQSAAVCARGKT
                     HQLTDLLNRMEALLNDVDACNVN"
     gene            50784..51662
                     /gene="citG"
                     /locus_tag="RN951_001345"
     CDS             50784..51662
                     /gene="citG"
                     /locus_tag="RN951_001345"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HDX2526366.1"
                     /translation="MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDR
                     INCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSAEMAPEAVLHGLRPIGMACEGDM
                     FRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTN
                     NSQLTAGQRLYQQLGLTGARGEAEAGYPLVINHALPHYLTLLDQGLDPELALLDTLLL
                     LMAINGDTNVASRGGEGGLRWLQREAQTLLQKGGIRTPADLDYLRQFDRECIERNLSP
                     GGSADLLILTWFLAQI"
     gene            51713..53176
                     /gene="citT"
                     /locus_tag="RN951_001346"
     CDS             51713..53176
                     /gene="citT"
                     /locus_tag="RN951_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate/succinate antiporter CitT"
                     /protein_id="HDX2526367.1"
                     /translation="MSLAKDNIWKLLAPLVVMGVMFLIPVPDGMPPQAWHYFAVFVAM
                     IVGMILEPIPATAISFIAVTICVIGSNYLLFDAKELADPAFNAQKQALKWGLAGFSST
                     TVWLVFGAFIFALGYEVSGLGRRIALFLVKFMGKRTLTLGYAIVIIDILLAPFTPSNT
                     ARTGGTVFPVIKNLPPLFKSFPNDPSARRIGGYLMWMMVISTSLSSSMFVTGAAPNVL
                     GLEFVSKIAGIQISWLQWFLCFLPVGVILLIIAPWLSYVLYKPEITHSEEVATWAGDE
                     LKTMGALTRREWTLIGLVLLSLGLWVFGSEVINATAVGLLAVSLMLALHVVPWKDITR
                     YNSAWNTLVNLATLVVMANGLTRSGFIDWFAGTMSTHLEGFSPNATVIVLVLVFYFAH
                     YLFASLSAHTATMLPVILAVGKGIPGVPMEQLCILLVLSIGIMGCLTPYATGPGVIIY
                     GCGYVKSKDYWRLGAIFGVIYISMLLLVGWPILAMWN"
     gene            53290..54096
                     /gene="rna"
                     /locus_tag="RN951_001347"
     CDS             53290..54096
                     /gene="rna"
                     /locus_tag="RN951_001347"
                     /EC_number="4.6.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease I"
                     /protein_id="HDX2526368.1"
                     /translation="MKAFWRNAALLAVSLLPFSSANALALQAKQYGDFDRYVLALSWQ
                     TGFCQSQHDRNRNERDECRLQTETTNKADFLTVHGLWPGLPKSVAARGVDERRWMRFG
                     CATRPIPNLPEARASRMCSSPETGLSLETAAKLSEVMPGAGGRSCLERYEYAKHGACF
                     GFDPDAYFGTMVRLNQEIKESEAGKFLADNYGKTVSRRDFDAAFAKSWGKENVKAVKL
                     TCQGNPAYLTEIQISIKADAINAPLSANSFLPQPHPGNCGKTFVIDKAGY"
     gene            54326..54736
                     /gene="rnk"
                     /locus_tag="RN951_001348"
     CDS             54326..54736
                     /gene="rnk"
                     /locus_tag="RN951_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside diphosphate kinase regulator"
                     /protein_id="HDX2526369.1"
                     /translation="MSRPTIIINDLDAERIDILLEQPAYAGLPIADALNAELDRAQMC
                     SPEEMPHDVVTMNSRVKFRNLSDGEVRVRTLVYPAKMTDSNTQLSVMAPVGAALLGLR
                     VGDSIHWELPGGVATHLEVLELEYQPEAAGDYLL"
     gene            complement(54967..56205)
                     /locus_tag="RN951_001349"
     CDS             complement(54967..56205)
                     /locus_tag="RN951_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent formaldehyde
                     dehydrogenase"
                     /protein_id="HDX2526370.1"
                     /translation="MKALTYHGPHHVQVENVPDPGVEQADDIILRITATAICGSDLHL
                     YRGKIPQVKHGDIFGHEFMGEVVETGKDVKNLQKGDRVVIPFVIACGDCFFCRLQQYA
                     ACENTNAGKGAALNKKQIPAPAALFGYSHLYGGVPGGQAEYVRVPKGNVGPFKVPPLL
                     SDDKALFLSDILPTAWQAAKNAQIQQGSSVAVYGAGPVGLLTIACARLLGAEQIFVVD
                     HHPYRLHFAADRYGAIPINFDEDSDPAQSIIEQTAGHRGVDAVIDAVGFEAKGSTTET
                     VLTNLKLEGSSGKALRQCIAAVRRGGIVSVPGVYAGFIHGFLFGDAFDKGLSFKMGQT
                     HVHAWLGELLPLIEKGLLKPEEIVTHYMPFEEAARGYEIFEKREEECRKVILVPGAQS
                     AEAAQKAVSGLVNAMPGGTI"
     gene            56426..56854
                     /gene="uspG"
                     /locus_tag="RN951_001350"
     CDS             56426..56854
                     /gene="uspG"
                     /locus_tag="RN951_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspG"
                     /protein_id="HDX2526371.1"
                     /translation="MYKTIIMPVDVFEMELSDKAVRHAEFLAQDDGVIHLLHVLPGSA
                     SLSLHRFAADVRRFEEHLQHEAQERLQTMVSHFTIDPSRIKQHVRFGSVRDEVNELAE
                     ELGADVVVIGSRNPSISTHLLGSNASSVIRHANLPVLVVR"
     gene            complement(56975..58540)
                     /gene="ahpF"
                     /locus_tag="RN951_001351"
     CDS             complement(56975..58540)
                     /gene="ahpF"
                     /locus_tag="RN951_001351"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017455864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HDX2526372.1"
                     /translation="MLDTNMKTQLKAYLEKLTKPVELIATLDDSAKSAEIKELLAEIA
                     ELSDKVTFKEDNSLPVRKPSFLITNPGSNQGPRFAGSPLGHEFTSLVLALLWTGGHPS
                     KEAQSLLEQIRHIDGDFEFETYYSLSCHNCPDVVQALNLMSVLNPRIKHTAIDGGTFQ
                     NEITDRNVMGVPAVFVNGKEFGQGRMTLTEIVAKIDTGAEKRAAEELNKRDAYDVLIV
                     GSGPAGAAAAIYSARKGIRTGLMGERFGGQILDTVDIENYISVPKTEGQKLAGALKVH
                     VDEYDVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGAKWRNMNVPGE
                     DQYRTKGVTYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLLEFAPEMKA
                     DQVLQDKLRSLKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNIELAGIFVQIG
                     LLPNTNWLEGAVERNRMGEIIIDAKCETNVKGVFAAGDCTTVPYKQIIIATGEGAKAS
                     LSAFDYLIRTKTA"
     gene            complement(58785..59348)
                     /gene="ahpC"
                     /locus_tag="RN951_001352"
     CDS             complement(58785..59348)
                     /gene="ahpC"
                     /locus_tag="RN951_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003858764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HDX2526373.1"
                     /translation="MSLINTKIKPFKNQAFKNGEFIEITEKDTEGRWSVFFFYPADFT
                     FVCPTELGDVADHYEELQKLGVDVYAVSTDTHFTHKAWHSSSETIAKIKYAMIGDPTG
                     ALTRNFDNMREDEGLADRATFVVDPQGIIQAIEVTAEGIGRDASDLLRKIKAAQYVAS
                     HPGEVCPAKWKEGEATLAPSLDLVGKI"
     gene            59720..60466
                     /gene="dsbG"
                     /locus_tag="RN951_001353"
     CDS             59720..60466
                     /gene="dsbG"
                     /locus_tag="RN951_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415137.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbG"
                     /protein_id="HDX2526374.1"
                     /translation="MLKKILLLALLPAIAFAEELPAPVKAIEKQGITIIKTFDAPGGM
                     KGYLGKYQDMGVTIYLTPDGKHAISGYMYNEKGENLSNTLIEKEIYAPAGREMWQRME
                     QSHWLLDGKKDAPVIVYVFADPFCPYCKQFWQQARPWVDSGKVQLRTLLVGVIKPESP
                     ATAAAILASKDPAKTWQQYEASGGKLKLNVPANVSTEQMKVLSDNEKLMDDLGANVTP
                     AIYYMSKENTLQQAVGLPDQKTLNIIMGNK"
BASE COUNT        15040 a        15480 c        15087 g        14954 t
ORIGIN      
        1 agctcctgca atatattgaa ttttcatgct tttgtaggcc ggataaggcg ttcacgccgc
       61 atccggcatg aacaaatcgc actttgtcag caatttggcc cccgtaaaat ataaacattc
      121 aataaaaccc gctaaaaatt atcgattcat caataaatat atcctcacac cagacctttt
      181 ttcaccaatc gacaatcacc attacgtttt ttattttttc accgccaaat cgcttgcgca
      241 cagtgctgct ttgcggcatt tttttaaaca agcaaacaca acaagcaaca aataccaggt
      301 taacggagaa ggttatgtgt tcaatttttg gcgtattcga tatcaaaaca gacgcagttg
      361 agctgcgtaa gaaagccctc gagctgtcac gcctgatgcg tcatcgtggc ccggactggt
      421 ccggtattta tgccagcgat aacgccattc tcgcccacga acgtctgtca attgttgacg
      481 ttaacgcggg ggcgcaacct ctctacaacc aacaaaaaac ccacgtactg gcggtaaacg
      541 gtgaaatcta caaccaccag gcattgcgcg ccgaatatgg cgatcgttac cagttccaga
      601 ccgggtctga ctgtgaagtg atcctcgcgc tgtatcagga aaaagggccg gaatttctcg
      661 acgacttgca gggcatgttt gcctttgcac tgtacgacag cgaaaaagat gcctacctga
      721 ttggtcgcga ccatctgggg atcatcccac tgtatatggg gtatgacgaa cacggtcagc
      781 tgtatgtggc ctcagaaatg aaagcgctgg tgccagtttg ccgcacgatt aaagagttcc
      841 cggcggggag ctatttgtgg agccaggacg gcgaaatccg ttcttactat catcgcgact
      901 ggttcgacta cgatgcggtg aaagataacg tgaccgacaa aaacgagctg cgtcaggcac
      961 tggaagattc agttaaaagc catctgatgt ctgatgtgcc ttacggtgtg ctgctttctg
     1021 gtggtctgga ttcctcaatt atttccgcta tcaccaagaa atacgcagcc cgtcgcgtgg
     1081 aagatcagga acgctctgaa gcctggtggc cgcagttaca ctcctttgct gtaggtctgc
     1141 cgggttcacc ggatctgaaa gcagcccaag aagtggcaaa ccatctgggc acggtgcatc
     1201 acgaaattca cttcactgta caggaaggtc tggatgccat ccgcgacgtg atttaccaca
     1261 tcgaaactta tgatgtgacc actattcgcg cttcaacacc gatgtattta atgtcgcgta
     1321 agatcaaggc gatgggcatt aaaatggtgc tgtccggtga aggttctgat gaagtgttcg
     1381 gcggttatct ttacttccac aaagcaccga atgccaaaga actgcatgaa gagacggtgc
     1441 gtaaactgct ggccctgcat atgtatgact gcgcgcgtgc caacaaagcg atgtcagcct
     1501 ggggcgtgga agcacgcgtt ccgttcctcg acaaaaaatt ccttgatgtg gcgatgcgta
     1561 ttaacccaca ggataaaatg tgcggtaacg gcaaaatgga aaaacacatc ctgcgtgaat
     1621 gttttgaagc gtatctgcct gcaagcgtgg cctggcggca gaaagagcag ttctccgatg
     1681 gcgtcggtta cagttggatc gacaccctga aagaagtggc tgcgcagcag gtttctgatc
     1741 agcaactgga aactgcccgc ttccgcttcc cgtacaacac gccaacctct aaagaagcgt
     1801 acttgtatcg ggagatcttt gaagaactat tcccgcttcc gagcgccgct gagtgcgtgc
     1861 cgggcggtcc ttccgtcgct tgttcttccg ctaaagcgat cgaatgggat gaagcgttca
     1921 agaaaatgga cgatccgtct ggtcgcgcgg ttggtgttca ccagtcggcg tataagtaag
     1981 aaatgcgaaa cagccccggt gaaatccggg gctgtttcag ttattgaggt gcttgttgat
     2041 tctgatatgc agtaaggaaa tgttccgggt ttgccacatc actgtttgac aactcatcac
     2101 tgtaggccag tatttcatag attaatttcc caccactatt gttaaattcc gaatttcatc
     2161 ctgtatgaca aaagaatggc tgtagggtgg gaaaaaacac aaagtaaaca ataattgacg
     2221 aatatagcgc cacgctgttc gcaacctaac caaacagtca ctttcgagca attttccttg
     2281 aaaaagaggt tgacgctgca aggctctata cgcataatgc gccccgcaac gccgataagg
     2341 tatcgcgaaa aaaaagatgg ctacgtagct cagttggtta gagcacatca ctcataatga
     2401 tggggtcaca ggttcgaatc ccgtcgtagc caccatcttt ttttgcggga gtggcgaaat
     2461 tggtagacgc accagattta ggttctggcg ccgcaaggtg tgcgagttca agtctcgcct
     2521 cccgcaccat tcaccagaaa gcgttgtacg gatggggtat cgccaagcgg taaggcaccg
     2581 gtttttgata ccggcattcc ctggttcgaa tccaggtacc ccagccatct tcttcgagta
     2641 agcggttcac cgcccggtta ttggggtatc gccaagcggt aaggcaccgg tttttgatac
     2701 cggcattccc tggttcgaat ccaggtaccc cagccatcga agaaacaatc tggctacgta
     2761 gctcagttgg ttagagcaca tcactcataa tgatggggtc acaggttcga atcccgtcgt
     2821 agccaccaaa ttctgaatgt gtcgaatatg ttcggcaaat tcaaaaccaa tttgttgggg
     2881 tatcgccaag cggtaaggca ccggattctg attccggcat tccgaggttc gaatcctcgt
     2941 accccagcca atttattcaa gacgcttacc ttgtaagtgc acccagttgg ggtatcgcca
     3001 agcggtaagg caccggattc tgattccggc attccgaggt tcgaatcctc gtaccccagc
     3061 cacattaaaa aagctcgctt cggcgagctt tttgcttttc tgcgttcatt caatgtcgaa
     3121 tgcgatgttg acacgtctta tccttcaatg tcggatgcga cgctgccgcg tcttatccga
     3181 cctacggttg gcacgcatcc ggcaatgttg taaggctaca accctaacgc atatttcagc
     3241 gcctgacgtt tcaacacgcc agcacgctcc gccgccatta acccgagatt acgcataaaa
     3301 cgcagtggtg gcagattatt gctgaatccg gcataaaaca gatccatacc gctttgcata
     3361 atgaagttat ccgccatgcg ccgcatctgg taacgcttga ggacaggata actggcccac
     3421 gcttcgccgt agctgcgggc gttgaccaga acatcaatca gggcatcgac atcacgataa
     3481 ccaagattca ctccctgccc cgccagcgga tggatggtat gcgcggcatc gcccaccagc
     3541 gcaagccctg gctgcacgta ctgcaacgca tggcgacgcg tcagcggaaa cgcaccagcg
     3601 gcaagcggtg taacgtaacc cagacgcgac gggaaatgct tcgcgatttc cgcctggagc
     3661 tgtgccatat tcatattctg caactggcga atacgcgccg gagagtcata ccacaccagc
     3721 gatgcccagt tatcaaacaa cggcagaaac gcacgcggtc cgtccggagt aaattgctgc
     3781 caggtgctgt cgccgggatc gttctcgcac tggacgctaa tcaacatgca cgactgcgca
     3841 tactgccatg catgaacgcc aattcccgcc atctgccgca cctgcgaatt tgcgccgtcg
     3901 gcaccaatca ccagcttcgc gcgaatcact tcaccgcctt tcagctccag ctcctgaaga
     3961 tcatcatggc gatgcagcgc aatcagcgag cctggcacac gtaacgttac tttcggatgc
     4021 gcttccagcg cctgccacaa cgcctgttgc aggacagtgt tttccaccat atagccaagc
     4081 agcggtagct taagttcagc ggcgtcaaac accacatgcg ccgtttccca ctcccacgtt
     4141 tccagtctgc ggtaaggatg gcaacgcata gcctgtactg catcccagac ccctaaccct
     4201 ttaagcaatg ataccgaagc cgcgctgatc gccgagatcc gcacgtccgg ttggctatca
     4261 gcgacaaacg gcgctggttc tgcgtgctcg atcaccgtta ccgcaaatcc gtgctgtgcc
     4321 agccccagcg ccagtgcgcc gccgaccatt cctccgccga caatggcaat ttccgttggt
     4381 tgatttgtca tggtcaatca tcctgttagc aatatgcttt aagtttacag gatttttacc
     4441 cctaagggct gataacgctc atactggtca caacggcagc aaagcattac actatgcgcc
     4501 ctgcattcct ggctactatt tcgcaagagc aagtcgatga ccaaaaaact ccatattaaa
     4561 acctggggct gtcagatgaa cgagtacgat tcatcgaaga tggccgatct gctggatgcc
     4621 acccacggct atcaactgac cgacgtggcg gaagaagcgg atgtgctgct gctgaacacc
     4681 tgctcaatcc gcgagaaggc tcaggaaaaa gtcttccatc agttgggtcg ctggaaactg
     4741 ttaaaagaga agaatccaga cctgattatc ggcgtcggtg gctgcgtggc atcgcaagaa
     4801 ggcgagcaca ttcgccagcg cgcccactat gtcgatatta tttttgggcc gcaaacgctg
     4861 caccgtctgc cggagatgat caactccgtg cgtggcgacc gcagcccggt tgtagatatc
     4921 agcttcccgg aaatcgagaa gtttgaccgt ctaccggaac cgcgcgccga agggccgacc
     4981 gcgtttgtct ccatcatgga aggctgcaat aaatattgca cctactgcgt ggtgccttac
     5041 acccgtggtg aagaggtaag ccgtccgtcc gacgatattc tgtttgagat tgcccagctt
     5101 gcggctcagg gcgtgcgtga agtcaacctg ctcggtcaga acgtgaacgc ctggcgtggt
     5161 gaaaactacg acggcaccac cggatcgttt gccgatctgc tgcgtctggt tgctgcgatc
     5221 gacgggatcg atcgtattcg ctttaccacc agccatccga tcgaattcac cgacgatatc
     5281 atcgaagtgt atcgcgacac gccggagctg gtgagcttcc tgcatctgcc ggtacagagc
     5341 ggttccgatc gcattctgaa cctgatgggc cgtacccata cggcgctgga gtacaaagcg
     5401 atcatccgta aactgcgtgc ggcgcgtcca gatattcaga tcagttctga tttcatcgtt
     5461 ggcttccctg gcgaaaccac cgaagacttc gagaaaacga tgaagctgat tgccgacgtc
     5521 aatttcgaca tgagctacag ctttatcttc tctgcacgtc cgggtacacc agccgccgat
     5581 atggttgatg atgttccgga agaagagaag aagcagcgtc tgtatattct gcaagagcgc
     5641 attaatcagc aagcgatggc gtggagccgc cggatgctcg gcaccaccca gcgtattctg
     5701 gtagaaggta catcgcgtaa gagcatcatg gagctttccg ggcgtacgga aaataaccgc
     5761 gtggtcaact tcgaaggcac gccggatatg atcggtaaat tcgtcgatgt agaaattacc
     5821 gacgtctacc cgaactctct gcgcggtaaa gtggtgcgta ctgaagatga aatgggtctg
     5881 cgcgtggcag aaacaccgga atcagtgatt gcccgtaccc gcaaagaaaa cgaccttggc
     5941 gtgggttatt atcagccgta attctcaggc ctgccgttcc ggtgggcctt gttttttctc
     6001 tctttatccc catctttatt gcaatgcttg cgcctttttc ctgtggcgtg aataatttcc
     6061 ttataggccg gtgaatgttc agcttccggc ggcatacaga taagaggaac ggtttgaaca
     6121 tagacactcg cgaaatcacc ctggagccag cagacaatgc gcgtctgttg agcctgtgcg
     6181 gcccgtttga tgacaacatc aagcagctcg aacgccgtct cggcatcgag atcaatcgcc
     6241 gcgataacca ctttaaactg accggccgtc cgatttgcgt caccgctgcg gcagacattc
     6301 tgcgtagcct gtatgtcgat actgccccga tgcgcggtca gattcaggat atcgaaccgg
     6361 aacagatcca ccttgcgatt aaagaagcgc gggtactgga gcaaagcgcg gagagcgtgc
     6421 cggagtacgg caaagcggtc aatatcaaaa ccaaacgcgg cgtaattaag ccgcgcacgc
     6481 caaaccaggc gcagtacatc gccaatattc tcgaccatga cattaccttc ggcgttggcc
     6541 cggcgggtac gggtaaaacc tacctggcag tggctgcggc agttgatgcc ctggagcgtc
     6601 aggaaattcg ccgtattctg ctgactcgtc cggcagtaga agccggtgag aaactgggct
     6661 tcctgcctgg cgatttaagc cagaaagtag acccgtatct gcgcccgctg tacgacgcgc
     6721 tgtttgaaat gctgggcttt gagaaagtcg agaaactgat tgagcgcaac gttattgaag
     6781 tcgcaccgct ggcctatatg cgtggtcgta cgctgaacga cgcgtttatc attctcgatg
     6841 agagccagaa caccaccatc gaacagatga agatgttcct gacccgtatc ggttttaact
     6901 caaaagcggt tatcaccggc gacgtcacac agatcgacct gccgcgtaat actaaatcag
     6961 gcttacgtca cgccatcgaa gtgctggccg atgtcgaaga gatcagcttt aacttcttcc
     7021 acagcgaaga cgtggttcgt caccctgtgg tggcgcgtat cgttaacgcc tatgaagcct
     7081 gggaagaagc cgaacaaaaa cgaaaagcgg cgctggcagc agaacgcaag cgcgaagaac
     7141 aggaacaaaa atgagtcagg tgatcctcga tttacaactg gcatgtgaag ataattccgg
     7201 gttaccggaa gagagccagt ttcagacatg gctgaatgcg gtgatcccgc agtttcagga
     7261 agaatcggaa gtgacgattc gcgtggtcga taccgccgaa agccacagtc tgaatctgac
     7321 ctatcgcggt aaggataagc cgaccaacgt gctctccttc ccgtttgaag tgccgcctgg
     7381 catggaaatg tcgctactgg gcgatctggt tatctgccgt caggtggttg agaaggaagc
     7441 tcaggagcaa ggcaaaccac tggaggcgca ctgggcgcat atggtggtgc acggcagtct
     7501 gcatttgtta ggttacgatc acatcgaaga tgacgaagca gaagaaatgg aagccctcga
     7561 aacagagatt atgcttgctc tgggctatga ggatccgtac attgccgaga aagaataatt
     7621 tgccaggcat ttgactggca gacgtccccg ccgttggtga ttaacgacgg cgttttgatt
     7681 aactaacatg agaacccata cgacgccatg agcgacgaca attcacacag tagtgacacg
     7741 ataagcaaca agaagggatt tttctccctg ttactcagcc aacttttcca cggtgaaccg
     7801 aaaaaccgtg acgaactgct ggcgctgatc cgtgattccg ggcagaacga ccttatcgac
     7861 gaagatacgc gcgatatgct cgaaggggtg atggacatcg cagaccaacg cgttcgcgac
     7921 atcatgatcc cccgctccca gatgattacc ctgaaacgca accagacgct ggacgaatgt
     7981 cttgatgtca tcatcgagtc cgcccactca cgtttcccgg tgattagcga agacaaagat
     8041 cacattgaag ggattctgat ggcgaaagac ttgctgccgt ttatgcgcag cgatgctgaa
     8101 gccttcagca tggacaaagt gttacgtcag gcggttgtcg ttcctgaaag taagcgcgta
     8161 gaccggatgc tgaaagagtt tcgctctcag cgttaccaca tggcgatcgt tattgacgaa
     8221 ttcggtgggg tttccggtct ggtgaccatt gaagacatcc tggaactgat tgttggtgag
     8281 attgaagacg agtatgacga agaagatgat atcgacttcc gtcagctgag tcgtcatacc
     8341 tggaccgtac gcgcactggc ttccattgaa gacttcaacg aagcgttcgg cacccacttt
     8401 agcgatgaag aagtcgacac tatcggtggt ctggtgatgc aggcatttgg gcatcttccg
     8461 gcgcgtggcg aaactatcga catcgacggt taccagttca aagtggcgat ggccgacagt
     8521 cggcgtatta ttcaggttca tgtcaaaatc ccggatgact caccccagcc gaagctggat
     8581 gaataaaacc gaaactggat agataactac atggcttttg cctcattaat tgaacgccag
     8641 cgcattcgcc tgctgctggc gttattattc ggtgcctgcg gaacgctggc cttctctcct
     8701 tacgacgtct ggcctgcggc gattatttcg ctgatggggc ttcaggcgtt gacctttaac
     8761 cgccgtccac tccagtctgc cgctattggc ttttgctggg gatttggcct ctttggcagc
     8821 ggtattaact gggtctatgt cagcatcgcg acctttggcg gaatgcctgg cccggttaac
     8881 atcttcctgg tggtgctgct ggcggcgtat ttgtcgctgt ataccggact gtttgctggc
     8941 gtgctgtcgc gtctgtggcc gaaaaccacc tggctgcgcg tagcgattgc cgcccctgcc
     9001 ctctggcaag tgaccgagtt tctgcgcggt tgggtactga ccggcttccc gtggttacag
     9061 ttcggctata gccagattga tggcccgtta aaagggctgg caccgataat gggcgtggaa
     9121 gccattaact tcctgctgat gatggttagt ggcctgctgg cactggcgtt ggtcaaacgc
     9181 aactggcgtc cgctggtggt ggccgtcgtg ctgtttgccc ttcccttccc gctgcgttac
     9241 atccagtggt ttaccccaca accggagaaa accattcagg tttcgatggt tcagggcgat
     9301 attccgcaat cgctgaaatg ggacgaaggc cagcttctta atacgctgaa gatttactac
     9361 aacgcaacgg caccgctgat gggcaaatca tcgttgatta tctggccgga gtcggcgata
     9421 accgatctgg aaattaatca gcaaccgttc ctcaaagcac tggacggtga gttgcgtgat
     9481 aaaggtagct cgctggtaac cgggattgtc gacgcgcgtc tcaataagca gaaccgctac
     9541 gatacctaca acaccatcat cacgctgggt aaaggtgcgc cgtacagcta cgaatcagcc
     9601 gatcgctata acaaaaacca tctggtgccg tttggcgagt ttgtcccgct ggagtcgatt
     9661 ctgcgtccgt tagcaccgtt ctttgatctg ccgatgtcgt cgttcagccg tgggccatat
     9721 atccagccgc cgctgtcggc aaatggtatt gagcttactg cggctatttg ctacgagatc
     9781 attctcggcg agcaagtgcg cgataacttc cgcccggata ccgactatct gctgactatc
     9841 tccaacgatg cgtggtttgg taaatctatt ggtccatggc aacacttcca gatggcgcga
     9901 atgcgtgcgc tggagctggc gcgcccactg ttgcgcagca ccaacaacgg cattacggcg
     9961 gtgattggcc cgcagggtga gattcaggcg atgatcccgc agttcacccg cgaggtgtta
    10021 accactaacg tgacgccgac caccggactc acaccatacg cacgtaccgg caactggccg
    10081 ctgtgggtgc tgacggcatt gtttggtttt gctgctgtgt tgatgagtct gcgtcagcga
    10141 cgtaaataat cccttcttat cgtgccggaa tacatcccat atttcggcac gctcaccgga
    10201 tgcggcatca gtgcattatc cggataacaa tattctccta tccaactttg gcacatctat
    10261 tgctttgtta tacaaggcaa accctgaatc agcatcagta caacctagtt gcaccacagt
    10321 aatccagcgg tagcactaaa agagtgcatt ttaagaattt tgcttcggaa tggtgcggcg
    10381 catctcgcaa aaacaaacaa taaaacagca atatctttac atttagccaa actaaatgtt
    10441 acctaacagg cacaacactg cacaataaag ttgcagacga taacaacaca aacactcaca
    10501 acgggtatcc atgcgttctt aacgcagaag ataaaggagt tggatatgca attacgtaaa
    10561 cctgccacag caatcctcgc cctggcgctt tccgcaggac tggcacaggc agatgacgcc
    10621 gccccggcag cgggcagtac tctggacaaa atcgccaaaa acggtgtgat tgtcgtcggt
    10681 caccgtgaat cttcagtgcc tttctcttat tacgacaatc agcaaaaagt ggtgggttac
    10741 tcgcaggatt actccaacgc cattgttgaa gcagtgaaaa agaaactcaa caaaccggac
    10801 ttgcaggtaa aactgattcc gattacctca caaaaccgta ttccactgct gcaaaacggc
    10861 actttcgatt ttgaatgtgg ttctaccacc aacaacgtcg aacgccaaaa acaggcggct
    10921 ttctctgaca ctattttcgt ggtcggtacg cgcctgttga ccaaaaaggg tggcgatatc
    10981 aaagattttg ccaacctgaa agacaaagcc gtagtcgtca cttccggcac tacctctgaa
    11041 gttttgctca acaaactgaa tgaagagcaa aaaatgaata tgcgcatcat cagcgccaaa
    11101 gatcacggtg actctttccg caccctggaa agcggtcgtg ccgttgcctt tatgatggat
    11161 gacgctctgc tggccggtga acgtgcgaaa gcgaagaaac cagacaactg ggaaatcgtc
    11221 ggcaagccgc agtctcagga ggcctacggt tgtatgttgc gtaaagatga tccgcagttc
    11281 aaaaagctga tggatgacac catcgctcag gtgcagacct ccggtgaagc ggaaaaatgg
    11341 tttgataagt ggttcaaaaa tccaattccg ccgaaaaacc tgaacatgaa tttcgaactg
    11401 tcagacgaaa tgaaagcact gttcaaagaa ccgaatgaca aggcactgaa ctaattacaa
    11461 gaaccagggg cggaaattcc agccctctcg attgttacgt agcacggaca gactatacgc
    11521 ctgatggtcg ttccccatcg ggcctgaaaa ccgcaatacg ctgggtaaca atcttcgagg
    11581 gtagcagtta acgctgctac cctctttttt ctggagtaga tttatgtcta tagactggaa
    11641 ctggggtatt tttttacaac aagccccgtt cggcaacacc acctatcttg gttggatctg
    11701 gagtggtttt caggtgacga tcgctttgtc gatctgcgcc tggattatcg ctttcctcgt
    11761 cggttcattt ttcggcattt tacgtaccgt tccaaaccgt tttctctctg gtctgggtac
    11821 gttgtatgtc gaactgttcc gcaacgtgcc gttgattgtg caattcttta cctggtatct
    11881 ggtgatcccg gagctgctgc cggagaaaat cggcatgtgg tttaaggccg agctggatcc
    11941 caatattcag tttttccttt catccatgct ctgcctgggg ctgtttaccg ccgcccgtgt
    12001 ttgcgaacag gtacgcgccg cgattcagtc gctgccgcga gggcaaaaaa atgccgcgct
    12061 ggcgatgggc ctgacgctac cgcaggctta tcgatacgta ctgctgccta atgcttatcg
    12121 cgttatcgtc ccgccgatga cctcagagat gatgaacctg gtgaaaaact ccgccatcgc
    12181 ctcgactatc ggtctggtgg atatggcggc gcaggcgggt aaattgctcg attactcagc
    12241 ccatgcctgg gagtcgttta ccgccattac gctggcgtat gtgttgatta acgcttttat
    12301 catgctggtg atgacgctgg ttgaacgtaa agttcgcctg cctggcaaca tggggggcaa
    12361 ataatgtacg agtttgactg gagttccatt gtcccttccc tgccatatct gctcgacggg
    12421 ctggtgatca ccctgaaaat caccgtcacg gcggtagtga ttggtatttt gtggggcacg
    12481 atgctggcgg tgatgcgttt atccagcttt gcgcccgtgg cgtggtttgc caaagcctac
    12541 gttaacgtat tccgctcgat tcctttagtt atggttttgc tgtggtttta cctgatcgtg
    12601 ccgggttttc tgcaaaacgt gctgggatta tcgccaaaaa atgatatccg tttaatttcg
    12661 gcgatggtgg cgttttcgat gtttgaagcg gcctactatt cagagattat ccgtgctggt
    12721 attcaaagta tttctcgtgg tcaatcgagc gccgcgctgg cgttgggaat gactcactgg
    12781 cagtcgatga aactgattat tctgccgcag gcgttccgcg cgatggtgcc gctgctgctc
    12841 actcagggca tcgtactgtt ccaggatacc tcactggtgt atgtgttatc cctggccgat
    12901 ttcttccgta ccgcctcaac cattggtgag cgtgatggta cgcaggttga gatgatcctg
    12961 tttgccggat ttgtttattt cgttattagt cttagcgcgt cgttgttggt cagctacttg
    13021 aaaagaagga cagcataatg attaccctga aaaatgtttc aaaatggtat ggtcactttc
    13081 aggtgctgac cgactgctca accgaagtga aaaaaggcga agtggtggtg gtttgcggcc
    13141 cgtctggttc cggcaaatca acgctgatta aaaccgtcaa cggcctcgaa ccggtgcagc
    13201 aaggtgaaat caccgtcgat ggtatcgtgg ttaacgacaa gaaaaccgat ctggcaaagc
    13261 tgcgttcccg cgtcgggatg gtattccagc atttcgagct gttccctcat ctgtcgatta
    13321 tcgaaaacct gaccctggcg caggtgaaag tgcttaaacg cgataaagcg ccggctcgtg
    13381 aaaaagccct gaaactgctg gagcgtgtcg ggctttctgc tcacgccaat aagtttccgg
    13441 cgcagctttc cggcggtcag cagcagcgtg tggcaatcgc tcgcgcgttg tgtatggatc
    13501 ctattgcgat gctgtttgac gaaccgacat cggcgctgga tccggagatg atcaacgaag
    13561 tactggacgt gatggtggaa ctggcgaacg aaggaatgac catgatggtg gtgacccacg
    13621 aaatgggctt tgcccgtaaa gtggcgaatc gggtgatctt tatggacgag ggtaaaattg
    13681 tcgaagactc gccgaaagac gctttcttcg atgatccgaa atcggaccgc gcaaaagact
    13741 tcctcgcgaa aatcctgcat taatcactct ggcgcgcata cccaattgcg cgccatctca
    13801 cgctttatcg tttcgcccct cgtatctgtt acatcctggc gttacccttg tcgcaaagaa
    13861 gcacacaaca aggagcaaca atggcactgc caattctgtt agattgcgac ccaggtcatg
    13921 acgacgctat cgcaatagtt ctcgccctcg cctcaccaga gcttgatgtc aaagcaatta
    13981 cgtcttccgc cggaaaccag acaccagaaa aaaccttacg caatgttctg cgtatgctga
    14041 ccttgcttaa tcgcaccgat attccggtag caggcggcgc ggtaaaaccg ttaatgcgtg
    14101 agttgattat cgcggacaat gtgcacggcg aaagcggtct cgacggcccg gcattaccgg
    14161 aaccgacatt cgcaccgcaa aactgtacgg cggtagagct gatggcgaaa acgctgcgtg
    14221 aaagtgcgga acctgtcacc attgtgtcta ccggaccgca aactaacgtt gccttgctgc
    14281 tcaatagcca tccggaactg catagcaaaa ttgcccgtat cgtgattatg ggtggcgcta
    14341 tggggctggg taactggacg cctgcggctg aatttaatat ttacgttgac ccggaagcgg
    14401 cagaaattgt cttccagtca gggatcccgg tggtgatggc cggtctggat gttactcata
    14461 aagcacaaat ccacgttgaa gacaccgagc gtttccgcgc gattggtaac cctgtttcaa
    14521 ccattgttgc cgaactgctg gatttcttcc tcgaatatca taaagacgaa aaatggggct
    14581 ttgtcggcgc accactgcat gacccatgca ccatcgcctg gctgttgaaa ccggagttat
    14641 ttacctctgt tgagcgctgg gttggcgtgg aaacacaggg gaaatatacc cagggtatga
    14701 cggttgttga ttattattat ctgacaggca ataaaccgaa tgccaccgta atggtcgatg
    14761 ttgatcgtca gggctttgtt gatttactgg ctgatcgtct gaaattttac gcttaacaca
    14821 cgtcattgat taagatcacc acgcgttacc tgggtggtct taatctgttt atctcttttt
    14881 ctttcaagat ataaatgcaa tggataatgc agaactcgcc attggtatcg atctcggtac
    14941 taccaatagt ttaattgccg tctggaaaga cggtgccgcg caattaattc caaataagtt
    15001 cggtgaatat ttaacaccat ccataattag catggatgaa aataatcata ttttagtcgg
    15061 aaaaccggct gtatcacggc gtacttcgca tccggataaa acggcagcgt tatttaaacg
    15121 tgcaatgggc agtaatacca actggcggtt aggcagcgac acatttaacg cgccagaact
    15181 gtcctctttg gtattacgct cattaaaaga agatgccgaa gaatttctgc aacgtccgat
    15241 taaagatgtg gtgatctccg ttccggctta tttcagcgat gaacaacgca agcatacccg
    15301 tttagcagcg gagttagccg ggttaaatgc ggtacgctta attaatgaac ccacagcagc
    15361 tgcgatggcg tatggcctgc atacccaaca aaatacccgt tcgctggtgt ttgatctcgg
    15421 tggcggcacg tttgacgtta cggtgcttga gtacgccacg ccggtgattg aagttcacgc
    15481 ctccgctggc gacaactttc ttggtggcga agattttacc catatgctgg tcgatgaggt
    15541 tttaaaacgc gcggatgtcg ccaggaccac gcttaacgag agtgaactgg cagccttgta
    15601 cgcctgtgtg gaagcggcaa aatgtagcaa tcaatcgcca ttgcacattc gctggcagta
    15661 tcaggaagaa acgcgggaat gcgaatttta cgagaacgaa ctggaagatt tgtggttgcc
    15721 gctgctcaat cgcttgcgag tgccgattga acaggcgttg cgcgatgcgc gtctgaagcc
    15781 gagtcaaatc gacagtctgg tgctggttgg cggcgcgtca caaatgccgc tggtgcagcg
    15841 aatcgccgtg cgtctgtttg gcaaattacc gtatcaaagt tacgatccga gcaccattgt
    15901 cgcgctgggc gcagcaatcc aggccgcctg ccgcttacgc agtgaagata ttgaagaggt
    15961 aatcctcact gatatttgcc cttactcgtt gggcgttgaa gttaaccgcc agggcgtttc
    16021 cggcattttc tcgccgatta ttgaacgaaa caccactgtg cccgtgtcgc gtgtagaaac
    16081 ttattcaacc atgcacccgg aacaggattc aattacggtt aacgtctatc agggagaaaa
    16141 ccacaaagtt aaaaacaaca ttctggtgga atccttcgat gtgccgttga agaaaaccgg
    16201 ggcttatcag tcgattgata ttcgctttag ttatgatatc aacgggttgc ttgaagttga
    16261 cgtgcttctg gaagacggca gcgttaagtc cagagtgatt aaccacagcc cggtaacatt
    16321 gagcgcgcag cagattgaag agagtcggac gcggttatcc gcattgaaaa tttatccgcg
    16381 cgatatgctc atcaatcgca cctttaaagc caaactggaa gagttgtggg cgcgggcgct
    16441 gggtgacgag cgagaagaga tcggccgggt gatcaccgat tttgatgcgg cgttgcagtc
    16501 aaacgatatg gcccgcgtgg atgaagttcg gcggcgggcg agcgattatt tagccattga
    16561 gatcccataa acacggctgc cggatgcggc gtaaacgctg catccggcat cggcgcaaaa
    16621 aacacatcgt cagctaaaca acatcgcgat tttgccgaga gcataaccta tcaccagcac
    16681 cgttaaactg attttgataa tgctggtaat gctctgtggt ttttcaccct catcattttt
    16741 ttcttcatga ttttcaggtg ttggctcatc gacatcttca tcctccggct cgagtttcac
    16801 tttcgtcaaa agcatccggg tgacaatggc ctctaatgga tgagcatctc cgccttccag
    16861 ccttgtatta agacgggcca gcatctcttg tttcggaaac gcttcaagta ctacctgttc
    16921 cgctacccga tacaaatcca ggaacggtga atcttgctct gtctcgctac cgactctcga
    16981 tttccaccac gcccatgctt tgcgcttgaa gaataacgac tcaataaacg attgacctaa
    17041 cggcgataat tttccgctat gtaaaatctc cgcccataac agccgcgtcc gggcgctctc
    17101 accaggaaca tatttcagcg gttgaccttg cgcatctacc atgctccgcg cttcgataac
    17161 catcactaat aacgcgaaat aatccgggca atgacgcttg ctccactgca acaacaaatt
    17221 atcagcttgt gtagatgggt aactttccca gtacgcgcag agatcggcaa gcaggctttc
    17281 cccctcgccg cagtacaaac gttgtgcaca caagtaatac cgggcatctt cgctttctgg
    17341 ttcttccgtt tgccactgtt gagcgacagg aatgagttcc gccatacctg tttgcaccga
    17401 gctgtaccag cgcaacagtt tgcgatgtaa ctttgcatca tcaggaatta accacggacc
    17461 ttccatcgcc aaaaacgcag tgacatagtc aggatggtaa cggcagcaac gttccagcgc
    17521 gaagtaatac tcaacagtct ggttctgcaa cgcaatggga tattccagaa ggctaaggaa
    17581 atcgaaacaa tcaccagcct gaatggcctc aagaaaagcc tccctttctt cctcatccat
    17641 tccttcgctg tcattaaatg aatgccagtt caaacgctct gccagcaaag aagcacaatt
    17701 taatgaaaga tatcgcgctt ctatggcgat tgcacacagc ggccagcgta attgatcgac
    17761 atcctccatg ttccaggtat ttaattgctg aataaatttc tgccaggcgg aaggctgaaa
    17821 acgatcactt tctgaatcca gtaatgtcct gaatgcacgt agtatttcat gttcagcggc
    17881 agcatctttt tcttcatcat ctgcttcctc gacaggattt accgccagtc gcagggcctc
    17941 ttcataggcc tggcgtaatg ctttaaaccc ttgcggatcg gtttcgggat gacacaacgg
    18001 taagcgagca agataagcct ggcggataat gtctatttgc gtcgtgcttt caatttcgag
    18061 gatttgccaa catgttttca taggtcgctc acatccttaa gcgttaccgg gcattcagac
    18121 tggacagtta atggctgcca gggaagcgtg gcatagaaac gatcgcttcc cgctgccagc
    18181 tcttcgaaca tacgactccc ggcgctatcg tatttgtaca gggttagcgc ctcgcgtagc
    18241 gaagtgttgt cttcgcactg agaagattgc cagtagagac gtcctaacga ataggcggaa
    18301 aaatagtgca tccagctgtg atagtaatgg tgagctcgta catagacgcg cgattgcagc
    18361 cataaactct cttcttccgt cagccacttg ttgagcacac cgacccgtga cagaaacccc
    18421 attcgaacat aatcccaggc tttgattccc ccttccccac agcacatagc ggtttgggca
    18481 acgaattggg tataaatcaa ccctctctcc gagccaccag caattaatgc tttccactct
    18541 tcaggggaag agcgatgcca tgtcagatat aagccagcta aatcattggc atgaccatca
    18601 tcagtcatct gataaatagt ctgaattaaa tcatcacgat tatttattcc ccaggatgat
    18661 gagagctcga attcttttat cccagtatac atttttggcg agtcatgcgc gggtttgcaa
    18721 ccctgattaa gtatttccat gggcgcagaa agcgcaaaaa gaagatattg ttcttcctta
    18781 ttcatttgtt aataatccct taagtgcatt aactgactac ttttttatta ttgatgagta
    18841 taaacttgac gctttcaaaa taaaaagaaa atcgaagcat tcacacatga ataaaaaatt
    18901 aatgtatata ttcgcaattt ttatagttgc agcaattacc tgtattagcc aacccaagaa
    18961 aacgacgttg cgtgataaag ccatggtgaa ttatgccttt gattatttaa gctcaccggg
    19021 cagtcttcca ttcaccacgg cagccacgga gctttccgcg attcatggtc actcaacgtc
    19081 gcaatatcgc cttggagaat tttatcttca tggtagcgac ggtaaaccac tggattatac
    19141 acaggcgaga tactggtatg agcaatcagc ggaacaggaa aatccacgcg cgcaaagtaa
    19201 actggggtgg atctacctca aaggtctggg ggtcaaaccc gacacccgta aagcaattct
    19261 ctggtataag gaagcagctg aacaagggta tgctcatgct caatatactt taggtttgat
    19321 ctacagaaat ggctcaggta ttaatgttaa ccattatgaa tctcaaaaat ggttaaaact
    19381 ggccgccaaa caacattaca aaaatgcgga aagattactt gccgggcttc ccgcacatta
    19441 acgtcgactg tcacccgaac agatggagta ttttccctat caaaccagca aagataaaaa
    19501 tatagaaaat aattttaatg atgcccagac agcctggccc accatcgtca acgggcattg
    19561 gctgcggttg cggctccggt tcaacagttt gcttctcggt aaaattcgcc gcctgaatta
    19621 ataatcgacg aataattaat gcttccagtg gacaacgatt ttctgcatca aggcggctca
    19681 caatcggcat taatgattct tctgtaggtt ggcaggcctg cactaattgt ttggcaacta
    19741 gatataatgg ccataaggta tgttctgtat cacgcgtgag tgagatccgc ggcttacgtc
    19801 ctttgtgcaa aaccatctcg accagtgaac gccccagcgc agagagtttt tcatcgctga
    19861 gtatttcgta taaatgaaaa cgcgtacggg cgctgtcgcc ggggacataa agtagcggtt
    19921 ttccctgatc gttaaccaga tcacgcgctt caatcatcat caccagtaat gggtaataat
    19981 cgacccgatg ctgacggcac cattgcaaca ttaaagcatc cgcctgggtg gagggatact
    20041 cgcgccagta gtcacaaagt tctgccaaca ggctttcgcc ttctccacaa tagacgcgtt
    20101 gcgcgtattc ataataaggc gcatcttcat tatcaggttc agtttcccgc catgactggg
    20161 cgtaatccag aagttcgggg atatccaggc gacctgcgct ataccagcgg agtaaatttc
    20221 tgtgcagttt tgcatcatcg gggataatca ctgcgcgatg ttgcgctaaa tacaatgtca
    20281 gccattgtgg atgcgatgac caaatccgag cgaacatttg gtaaaaatcg atggtgtcat
    20341 tttgcacggc aacgggcaga tgcagaatgg tctggaagtt aaaaacattc cccttcgcaa
    20401 tggcatataa aaaggattcc agttcttctt cgtctatttc cccggtattt tcctcctgta
    20461 accaccgcaa tctttctgct aataacacca cgcactcgaa ggataaatgg gcagtgttca
    20521 tggcgattgt gcacagcgac cagcgtaatt catcaatctc ctccatcgag caataattta
    20581 attgctgaat gaatcgctgc caggcggagg gcagaaaacg ttcactatca gaggcaagta
    20641 acgcacgaaa ggcgagcaga atttcatgtt ctgctacctc atattcttct ggttgccaaa
    20701 cagatttagc aggcgactgc gcaatccgta gcgcctcctc atacgcctga cgaagttgtt
    20761 taaaaccctg cggatcggtt tctggatgaa aggacggtaa cagcgccaga taagcgcggc
    20821 ggataatatc gacgtcagtc gtttcctcta tatcgaggat cttccagcaa tttttcatag
    20881 gtcgctcata tccttaagcg tttccgggca tgcagaatag taagccaatg gttgccagga
    20941 caaggtaggg taatacgcat catcactggc aaataattga taaaacatat cattgccgga
    21001 atcgtcgtat tctttacgcg ctaagaattc gcgtaataaa ggcagatgat catcttcggg
    21061 agactgccaa tattgccgac caaaggtata accggcaaag tattgccgcc agttactata
    21121 ataacgtaga gcccgtagat gaatgcgcga ctggatccat agactttctt cttcgctcaa
    21181 ccagttatta agtacgccca ttcggcttaa aaaacccatc cggacataat cccaggcttt
    21241 gattccccct tcgccacagc attcggcggt gctggcgaca aattgcgcat aagcctgacc
    21301 ttgctcattt agttcagcaa gatagtcacg ccattcacat ggcgaataac gaaaccagcg
    21361 gtgataaaac cctgccaacc gagcggcatg accgttatcg atcattcggt gaattgtgcg
    21421 cagcaggtca tcacggtcat caattcccca tgaggaagaa aggtcgaaaa agcatgtacc
    21481 taaatacatt ttgggtgatg aatgcgaagg taaacagcat tcattgcgta tttccatcgg
    21541 agtggaaagt gcaaacaata ttttttgcga ctccatgtcc atataattta tccttaaata
    21601 ttcattaaat gaatattagc cgcattgcga ggctcgttta tttatacttt tctgacgcga
    21661 cataatacgc ataaaataag gcttacgcaa aaatggaaca cataaaaata taatatgttt
    21721 tatctgcaac cataaggaaa tgataatgat tttcacgtca agttgctgcg ataatttatc
    21781 aatagatgag attatcgaac gtgctgaaaa aggcgattgc gaggctcaat atattgttgg
    21841 gttttattat aatcgcgata gcgcaattga ttctccggac gacgaaaaag ccttttactg
    21901 gctgaagctg gccgctgagc aaggtcattg tgaagcacag tattccttag ggcaaaagta
    21961 taccgaggat aaaagccgtc ataaagataa tgagcaagcc atcttctggc tgaaaaaagc
    22021 tgccctacaa ggccatactt tcgcttccaa cgcccttggc tggacactgg atcgtggaga
    22081 agcccccaat tataaagaag cggttgtctg gtatcagata gccgcggaga gcggaatgtc
    22141 ttatgcgcaa aataatcttg ggtggatgta cagaaatggc aacggagtcg caaaagacta
    22201 tgcgctggca tttttctggt acaaacaagc tgcattacaa ggccatagtg acgcgcaaaa
    22261 caatctggcc gatctttatg aagacggaaa aggcgttgct caaaacaaga cactcgccgc
    22321 attctggtat ttgaaaagcg cacagcaggg taatcggcac gcccagtttc aaattgcatg
    22381 ggattataac gctggcgaag gggtggacca ggactataag caagcgatgt actggtatct
    22441 gaaggctgcc gctcagggga gcgtcggcgc ttacgtcaac atcggttata tgtataaaca
    22501 cggacaaggc gttgagaaag attatcaggc tgcctttgaa tggtttacga aagccgctga
    22561 atgcaatgac gccactgcct ggtataacct ggccattatg tatcactacg gagaaggaag
    22621 acctgtcgat ctccgacagg ctctcgacct gtatcgtaaa gttcagtcat ccggaaccag
    22681 agatgtcagt caggaaattc gtgagactga agatttactg tagagataaa aacaagggcc
    22741 ggggaatttc attcggccca tattctcttt attgctgtgc gaaatcagac tattacggct
    22801 caaacgggcg tctctggaac tggtcatgac cacatttcgg gcatagcgtc agcacttccg
    22861 gtgtgtagat cgggagatgg aagtgacatt tctcgcagac cagatttccc agcccgacca
    22921 cttctccgct gtgataaacc ccatgatgat tgaggtcctg gaaaacttcg cgccattcaa
    22981 gctgcgtttt atcggtgatg tctgccagct cctgccacaa gctttcttta atcacccgca
    23041 taaagacgct gtcagattct tctttcaggc tctcttcata actcatggcg aactcttcca
    23101 ggtcacgtct gacagctcgc gtcagctcat cgacctcggt tcgcgttaac tcccctgttt
    23161 ttattacgcg ctcgcgcgcc tgttccacca gtgcgtcgat atcacgttcg ccattgcgca
    23221 ggcgttcgct cagtgacgca accagttcac ggtaatattg agcaaccttg ttcatcgttt
    23281 catctcccgg gtcgttaact gactataata atagacgttc tttgttcctt gctttgctaa
    23341 tacgcccaca aactctgtaa attaatgtat gaataatccg ggcatcattt caacgtcgag
    23401 tgcgcgaaag gctgttttga cgcggacgtt tgggctatgc tatgcggatc tgaaaaacca
    23461 cctcaacgct acatttgtag ccgtattgaa aacaggacca ctggctgcca tgcaagagca
    23521 ataccgcccg gaagagatag aatccaaagt acagcttcat tgggatgaga agcgcacatt
    23581 tgaagtaacc gaagacgaga gcaaagagaa gtattactgc ctgtctatgc ttccctatcc
    23641 ttctggtcga ctacacatgg gccacgtacg taactacacc atcggtgacg tgatcgcccg
    23701 ctaccagcgt atgctgggca aaaacgtcct gcagccgatc ggctgggacg cgtttggtct
    23761 gcctgcggaa ggcgcggcgg tgaaaaacaa caccgctccg gcaccgtgga cgtacgacaa
    23821 catcgcgtat atgaaaaacc agctcaaaat gctgggcttt ggttatgact ggagccgcga
    23881 gctggcaacc tgtacgccgg aatactaccg ttgggaacag aaattcttca ccgagctgta
    23941 taaaaaaggc ctggtatata agaagacttc tgcggtcaac tggtgcccga acgaccagac
    24001 cgtactggcg aacgaacaag ttatcgacgg ctgctgctgg cgctgcgata ccaaagttga
    24061 acgtaaagag atcccgcagt ggtttatcaa aatcactgct tacgctgacg agctgctcaa
    24121 cgatctggat aaactggatc actggccaga caccgttaaa accatgcagc gtaactggat
    24181 cggtcgttcc gaaggcgtgg agatcacctt caacgttaac gactatgaca acacgctgac
    24241 cgtttacact acccgcccgg acacctttat gggttgtacc tacctggcgg tagctgcggg
    24301 tcatccgctg gcgcagaaag cggcggaaaa taatcctgaa ctggcggcct ttattgacga
    24361 atgccgtaac accaaagttg ccgaagctga aatggcgacg atggagaaaa aaggcgtcga
    24421 tactggcttt aaagcggttc acccattaac gggcgaagaa attcccgttt gggcagcaaa
    24481 cttcgtattg atggagtacg gcacgggcgc agttatggcg gtaccggggc acgaccagcg
    24541 cgactacgag tttgcctcta aatacggcct gaacatcaaa ccggttatcc tggcagctga
    24601 cggctctgag ccagatcttt ctcagcaagc cctgactgaa aaaggcgtgc tgttcaactc
    24661 tggcgagttc aacggtcttg accatgaagc ggccttcaac gccatcgccg ataaactgac
    24721 tgcgatgggc gttggcgagc gtaaagtgaa ctaccgcctg cgcgactggg gtgtttcccg
    24781 tcagcgttac tggggcgcgc cgattccgat ggtgacgctg gaagacggta ccgtaatgcc
    24841 gaccccggac gaccagctgc cggtgatcct gccggaagat gtggtaatgg acggcattac
    24901 cagcccgatt aaagcagatc cggagtgggc gaaaactacc gttaacggta tgccagcact
    24961 gcgtgaaacc gacactttcg acacctttat ggagtcctcc tggtactatg cgcgctacac
    25021 ttgcccgcag tacaaagaag gtatgctgga ttccgaagcg gctaactact ggctgccggt
    25081 ggatatctac attggtggta ttgaacacgc cattatgcac ctgctctact tccgcttctt
    25141 ccacaaactg atgcgtgatg caggcatggt gaactctgac gaaccagcga aacagttgct
    25201 gtgtcagggt atggtgctgg cagatgcctt ctactatgtt ggcgaaaacg gcgaacgtaa
    25261 ctgggtttcc ccggttgatg ctatcgttga acgtgacgag aaaggccgta tcgtgaaagc
    25321 gaaagatgcg gcaggccatg aactggttta taccggcatg agcaaaatgt ccaagtcgaa
    25381 gaacaacggt atcgacccgc aggtgatggt tgaacgttac ggcgcggaca ccgttcgtct
    25441 gtttatgatg tttgcttctc cggctgatat gactctcgaa tggcaggaat ccggtgtgga
    25501 aggggctaac cgcttcctga aacgtgtctg gaaactggtt tacgagcaca cagcaaaagg
    25561 tgatgttgcg gcactgaacg ttgatgcgct gactgaaaat cagaaagcgc tgcgtcgcga
    25621 tgtgcataaa acgatcgcta aagtgaccga tgatatcggc cgtcgtcaga ccttcaacac
    25681 cgcaattgcg gcgattatgg agctgatgaa caaactggcg aaagcaccaa ccgatggcga
    25741 gcaggatcgc gctctgatgc aggaagcact gctggccgtt gtccgtatgc ttaacccgtt
    25801 caccccgcac atctgcttca cgctgtggca ggaactgaaa ggcgaaggcg atatcgacaa
    25861 cgcgccgtgg ccggttgctg acgaaaaagc gatggtggaa gactccacgc tggtcgtggt
    25921 gcaggttaac ggtaaagtcc gtgccaaaat caccgttccg gtggacgcaa cggaagaaca
    25981 ggttcgcgaa cgtgctggcc aggaacatct ggtagcaaaa tatcttgatg gcgttactgt
    26041 acgtaaagtg atttacgtac caggtaaact cctcaatctg gtcgttggct aagcgcggga
    26101 ggaagcgtgc gatatctggc aacattgttg ttatctctgg cggtgttaat caccgccggg
    26161 tgtggctggc atctgcgtga taccacgcag gttccttcca ctatgaaggt catgatcctg
    26221 gactcaggcg atccgaacgg gccattaagc cgtgcggtgc gtaaccagtt acgtctgaat
    26281 ggtgtcgagt tgcttgataa agaaaccacg cgtaaggacg ttccatcctt gcgtttgggt
    26341 aaagtgagca tcgcgaaaga taccgcatcg gtattccgta acggtcaaac agcagagtat
    26401 cagatgatca tgacggttaa tgcgaccgtg ttgatccccg gccgtgatat ctacccgatt
    26461 agcgccaaag tcttccgttc gttcttcgat aacccgcaaa tggcgttagc gaaagataac
    26521 gaacaagaca tgatcgtaaa agagatgtac gaccgtgctg ccgaacagct gattcgtaag
    26581 ctgccaagca tccgtgctgc ggatattcgt tccgacgaag aacagacgtc gaccacaacg
    26641 gatactccgg caacgcctgc acgcgtctcc accacgctgg gtaactgatg attcggttgt
    26701 acccggaaca actccgcgcg cagctcaatg aagggctgcg cgcggcgtat cttttacttg
    26761 gtaacgatcc tctgttattg caggaaagcc aggacgctgt tcgtcaggta gctgcggcac
    26821 aaggattcga agaacaccac actttttcca ttgatcccaa cactgactgg aatgcgatct
    26881 tttcgttatg ccaggctatg agtctgtttg ccagtcgaca aacgctattg ctgttgttac
    26941 cagaaaacgg accgaatgcg gcgatcaatg agcaacttct cacactcacc ggacttctgc
    27001 atgacgacct gctgttgatc gtccgcggta ataaattaag caaagcgcaa gaaaatgccg
    27061 cctggtttac tgcgcttgcg aatcgcagcg tgcaggtgac ctgtcagaca ccggagcagg
    27121 ctcagcttcc ccgctgggtt gctgcgcgcg caaaacagct caacttagaa ctggatgacg
    27181 cggcaaatca ggtgctctgc tactgttatg aaggtaacct gctggcgctg gctcaggcac
    27241 tggagcgttt atcgctgctc tggccagacg gcaaattgac attaccgcgc gttgaacagg
    27301 cggtgaatga tgccgcgcat ttcacccctt ttcattgggt tgatgctttg ttgatgggaa
    27361 aaagtaagcg cgcattgcat attcttcagc aactgcgtct ggaaggcagc gaaccggtta
    27421 ttttgttgcg cacattacaa cgtgaactgt tgttactggt taacctgaaa cgccagtctg
    27481 cccatacgcc actgcgtgcg ttgtttgata agcatcgggt atggcagaac cgccggggca
    27541 tgatgggcga ggcgttaaat cgcttaagtc agacgcagtt acgtcaggcc gtgcaactcc
    27601 tgacacgaac ggaactcacc ctcaaacaag attacggtca gtcagtgtgg gcagagctgg
    27661 aagggttatc tcttctgttg tgccataaac ccctggcgga cgtatttatc gacggttgat
    27721 atgaaatctt tacaggctct gtttggcggc acctttgatc cggtgcacta tggtcatcta
    27781 aaacccgtgg aaacgctggc gaatttgatt ggtctgacgc gggtcacaat catccctaat
    27841 aatgttcctc cgcatcgtcc ccagccggaa gcgaacagcg tgcagcgtaa acacatgctt
    27901 gaactggcga ttgccgacaa gccattattt actcttgatg aacgcgagct aaagcgcaat
    27961 gccccctctt acactgcgca aacactgaaa gagtggcggc aggaacaagg accggacgtg
    28021 ccgctggcgt ttattattgg tcaggattca ctgctgacct ttccgacctg gtacgaatac
    28081 gaaacgatac tcgacaatgc acatttgatc gtctgtcggc gtccaggtta cccacttgaa
    28141 atggcgcaac cgcaatacca gcaatggctg gaagatcatt tgacacataa cccggaagat
    28201 cttcaccttc agcctgccgg taaaatttat ctggctgaaa cgccgtggtt taacatctcg
    28261 gcgaccatca tccgcgaacg tttgcaaaac ggtgaatcat gtgaggattt attgccggaa
    28321 ccggtactga cttacattaa ccaacaaggc ttgtatcgct gatacctgtc gttacggagg
    28381 gcatgatgcg actgtggtta attcgtcatg gtgaaacgca agcgaatatc gatggtcttt
    28441 acagcggtca tgcgcccacc cccctgaccg cgcgcggtat tgagcaagcg caaaatctgc
    28501 atacgctgct acatggtgtt tcctttgatc tggttttatg cagtgaactg gaacgggcac
    28561 agcataccgc gcgactggtt ctcagtgacc gccagctccc cgtgcaaatc atacctgaac
    28621 tcaacgaaat gttttttggc gactgggaga tgcgacatca tcgcgacctc atgcaagaag
    28681 atgccgaaaa ctatagcgcg tggtgcaatg actggcagca tgcaatcccc acgaacggtg
    28741 aaggatttca ggcattttcg caacgtgtgg aacgctttat cgcaaggctt agtgaatttc
    28801 agcactatca gaatatttta gtcgtcagcc atcagggtgt actgagtctg ttaatcgccc
    28861 gtttaattgg catccctgcc gaggctatgt ggcattttcg cgttgaccag gggtgttgga
    28921 gcgccattga tatcaaccaa aaattcgcga cgctacgcgt cctcaatagc cgtgccatcg
    28981 gggtcgagaa tgcatgactt ttctgttttt ttacgggtaa gccgcaacga ccattgacag
    29041 acccgggcag gctgatattc tccgcagcca gactttttcc gccagacacg actttgtaga
    29101 aattgtttta caaaaatggc gatgcaatct gcggcgcggg gtgggatgat agcccacttt
    29161 cgaaagccga ttcggcgaca attgtcccga aatcgcctct ggttcaggta tactgacaga
    29221 ccatttttat ctatttgatt cacccagggg gaaaacttgc agggtaaagc actccaggat
    29281 tttgttatcg acaaaattga tgacctcaaa ggtcaggaca tcatcgcctt agacgttcag
    29341 ggcaaatcca gcatcaccga ctgcatgatc atctgtacgg gtacgtccag ccgtcatgtt
    29401 atgtccattg ctgaccacgt tgtgcaggag tctcgcgcag cgggcctgtt accgctcggc
    29461 gtagaaggtg aaaacagcgc cgactggatt gtcgtggatt tgggcgatgt gattgtccat
    29521 gtcatgcagg aagagagccg tcgcctgtat gaactggaaa aactctggag ttaatgcgtg
    29581 aagctgcaac ttgtcgccgt gggaacgaaa atgccggact gggtacaaac cggttttacc
    29641 gagtacctgc gtcgttttcc gaaagatatg cccttcgagc tgattgaaat tccggccgga
    29701 aaacgcggca agaatgcgga catcaagcgc atactcgaca aagagggtga gcagatgttg
    29761 gcggccgcag gcaaaaaccg cattgtcacc ctcgatattc caggcaagcc ctgggatacg
    29821 ccgcagttag ccgctgagct ggaacgctgg aagctggatg gtcgcgacgt cagtctactg
    29881 attggcgggc ctgaagggtt gtcgcctgcc tgtaaagcgg cggctgagca gagctggtcg
    29941 ctgtcggcgc ttaccctccc ccatccgctg gttcgcgtgc tggtcgcaga gagtctgtac
    30001 cgggcgtgga gcatcaccac caaccatcct tatcaccgtg agtgataagg gagctttgag
    30061 tagaaaacgc agcggatgaa actacagaac tcttttcgcg actatacggc agagtccgcg
    30121 ctgtttgtgc gccgggcgct ggtcgccttt ttggggattt tgctgctgac cggcgtgctt
    30181 atcgccaacc tgtataatct gcaaattgtt cgctttaccg actaccagac ccgctctaat
    30241 gaaaaccgca ttaagctggt gcctatcgcg cccagccgcg gcattatcta cgatcgtaac
    30301 ggtatccctc tggccctcaa ccgcactatc taccagatag aaatgatgcc ggagaaagtc
    30361 gataacgtgc agcaaacgct ggacgctttg cgcagcgtgg tagatctgac cgatgacgat
    30421 attgctgcat tccgaaaaga gcgcgcacgt tcacaccgtt tcacctctat tccggtgaaa
    30481 actaacctga ccgaagtaca agtagctcgc tttgccgtca atcagtaccg ttttccgggt
    30541 gtcgaagtta aaggctataa acgtcgttac tatccttacg gttcggcgtt gacccacgtc
    30601 atcggctatg tgtcgaaaat caacgataaa gacgtcgaac gcctgaataa tgacggcaaa
    30661 ctggccaact atgcggcaac gcatgatatc ggtaagctgg gcattgagcg ttactatgaa
    30721 gatgtgctgc acggtcagac cggttatgaa gaggttgaag ttaacaaccg tgggcgtgtt
    30781 attcgccagt taaaagaagt accaccgcaa gccggacacg atatttacct gacgctggat
    30841 ctcaaactcc agcaatatat tgaaacgctg ctggcgggta gccgcgcagc tgtggtagtc
    30901 accgatccgc gtacaggtgg ggtgctggcg ctggtttcca cgcctagtta tgacccaaac
    30961 ttgtttgttg acggtatctc cagcaaagat tattccgcct tgttgaacga tccgaataca
    31021 ccgctggtga accgcgccac acagggggtt tatcctcccg cgtctacagt taaaccctat
    31081 gtggcggttt cggcattgag cgccggggtg atcacgcgca atacgacgct gtttgaccca
    31141 ggctggtggc aactgccagg ttcggaaaaa cgttatcgtg actggaaaaa atggggccac
    31201 gggcgtctga atgtcacaag atcgctggaa gaatctgcgg ataccttctt ctatcaggtg
    31261 gcctacgata tggggatcga tcgcctctcc gaatggatgg gtaaattcgg ttatggtcat
    31321 tacaccggta tcgacctggc ggaagaacgt tccggcaaca tgcctacccg cgaatggaaa
    31381 cagaaacgct ttaaaaaacc gtggtatcag ggtgacacca ttccggttgg tatcggtcag
    31441 ggttactgga cagcgacccc aatccagatg agtaaggcac tgatgatcct gattaatgac
    31501 ggtatcgtga aggttcctca tttgctgatg agcaccgccg aagacggcaa acaggtgcca
    31561 tgggtacagc cgcatgaacc gcccgtcggc gatattcatt ccggttactg ggagctggcg
    31621 aaagacggta tgtacggtgt tgctaaccgc cctaacggta cggcgcataa atactttgct
    31681 agcgcaccgt acaaaattgc ggcgaaatcc ggtaccgctc aggtcttcgg tctgaaagcg
    31741 aacgaaacct ataatgcgca caaaattgcc gagcgtttac gtgaccacaa actgatgacc
    31801 gcctttgcgc catacaacaa tccgcaagtg gctgtcgcca tgattctgga gaacggtggt
    31861 gcgggtccgg cggttggtac actgatgcgc cagatcctcg accacattat gctgggtgat
    31921 aacaacaccg atctgcctgc ggaaaatcca gcggttgccg cagcggagga ccattaatca
    31981 tgacggataa tccgaataaa aaaacattct gggataaagt ccatctcgat cccacaatgc
    32041 tgctgatctt actggcattg ctggtttaca gcgccctggt tatctggagc gccagcggtc
    32101 aggatattgg catgatggag cgtaaaatcg gccaaatcgc gatgggtctg gtcatcatgg
    32161 tggtgatggc gcaaattcct ccacgcgttt atgaaggctg ggccccctat ctctatatca
    32221 tctgtattat tttgctggtg gcggtagatg ctttcggtgc catctctaaa ggtgctcaac
    32281 gctggctgga cctcggtatt gttcgttttc agccgtcgga aattgccaaa atagccgtac
    32341 cactgatggt tgcgcgcttt atcaaccgcg acgtttgccc gccatcgttg aagaacactg
    32401 gcatcgcgct ggtgctgata tttatgccca cgctgctggt ggctgcacag cctgacctgg
    32461 gaacatcaat cctcgttgcg ctttccggtc tgtttgtact gttcctctct ggccttagct
    32521 ggcgtctgat tggcgtcgca gtagtgctgg tagcggcgtt cattccgatt ctgtggttct
    32581 tcctgatgca tgattaccag cgccagcgcg taatgatgct cctggacccg gaatcagacc
    32641 cactcggcgc gggctatcac attattcagt ctaaaattgc tattggctcc ggcggattac
    32701 gcggcaaagg ctggctgcac ggcactcagt cacagcttga atttctcccc gaacgccata
    32761 ctgactttat cttcgcggta ctggcggaag agctgggatt agtgggcatt ctgattctgc
    32821 tcgctctcta cattctgctg atcatgcgcg ggctgtggat agccgccaga gcgcaaacca
    32881 cctttggtcg cgtcatggct ggcggcttaa tgctgatatt attcgtttat gtcttcgtaa
    32941 atattggtat ggtaagcggt attctgccgg ttgtaggggt tccgctccca ctggtcagtt
    33001 atggaggatc ggcgctaatt gtgctgatgg ctgggttcgg gattgtaatg tcaatccaca
    33061 cccacaggaa aatgttgtcg aaaagcgtgt aagaggtgcg caatgcgtaa gcagtggctc
    33121 gggatctgca tcgcggcagg aatgctcgcg gcatgtacaa gcgatgatgg tcagcaacag
    33181 acggtaagtg taccgcagcc tgcggtatgt aacggcccta tagttgaaat tagcggggcg
    33241 gacccgcgtt tcgaaccact gaacgcgacg gcaaatcagg attaccagcg cgacggtaaa
    33301 agctacaaaa tcgtgcagga tccgtctcga tttagccagg cgggactggc ggcaatctat
    33361 gatgccgaac ccggcagtaa cctgacggcc tctggcgaag cattcgatcc gacacagctg
    33421 acggcagccc atccaacgct tccgatcccc agctacgcca gaatcactaa cctggctaac
    33481 gggcgaatga tcgtggtgcg cattaatgat cgcggccctt acggcaacga ccgcgttatt
    33541 tcactttctc gcgcggcagc tgaccgtctt aacacgtcaa acaacaccaa agttcgtatc
    33601 gatccgatta ttgttgccca ggatggttcg ctttctggtc ctggtatggc ttgtaccaca
    33661 gtcgccaaac agacttacgc cctgcctgca cctcccgatt taagcggtgg cgcgggaaca
    33721 agttcagtgt ctggcccgca gggtgacatt cttccggtca gtaattcgac gctaaaaagc
    33781 gaagatccga ccggcgcgcc ggtaaccagt agcggtttcc tcggcgcacc aacgacctta
    33841 gcgcctggtg tactggaagg cagcgaaccg acgcctgcgc cacagcccgt tgttacagct
    33901 ccgtcgacaa cgcctgcaac ctcgcctgca atggtgacac cgcaagccgt ctcgcaaagc
    33961 gccagcggca actttatggt gcaagtcggg gccgtaagcg atcaggctcg tgcgcaacag
    34021 taccaacagc aactgggaca gaagttcggc gtccccggtc gcgtaactca aaatggcgcg
    34081 gtctggcgga tccagcttgg cccattcgcc agcaaagccg aagccagtac cttgcagcaa
    34141 cgtttgcaaa ccgaagccca attacagtca tttattacta ccgcgcagta gcgtaaagca
    34201 ggcatctgat gtgtcaattt ctgtaaatga cgttaacaaa gtcacgcgga aagtcagatg
    34261 cctgccggta gtgcatttgc tatagtaggg cactttttta attccatcac ggatgtcgta
    34321 gttcagacca tgaataccat tttttccgct cgtatcatga agcgcctggc gctcaccacg
    34381 gctctttgca cagcctttat ctctgctgca catgccgatg acctgaatat caaaactatg
    34441 atcccgggtg taccgcagat cgatgcggag tcctacatcc tgattgacta taactccggc
    34501 aaagtgctcg ccgaacagaa cgcagatgtc cgccgcgatc ctgccagcct gaccaaaatg
    34561 atgaccagtt acgttatcgg ccaggcaatg aaagccggta aatttaaaga aactgattta
    34621 gtcactatcg gcaacgacgc atgggccacc ggtaacccgg tgtttaaagg ttcttcgctg
    34681 atgttcctca aaccgggcat gcaggttccg gtttctcagc tgatccgcgg tattaacctg
    34741 caatcgggta acgatgcttg tgtcgccatg gccgattttg ccgctggtag ccaggacgct
    34801 tttgttggct tgatgaacag ctacgttaac gcactgggcc tgaaaaatac ccacttccag
    34861 acggtacatg gtctggatgc tgatggtcag tacagctccg cgcgagatat ggcgctgatc
    34921 ggccaggcat tgatccgtga cgtaccgaat gaatactcga tctataaaga aaaagaattt
    34981 acgtttaacg gtattcgcca gctgaaccgt aacggcctgt tatgggataa cagcctgaat
    35041 gtcgacggca tcaaaaccgg acacactgac aaagcaggtt acaaccttgt tgcttctgcg
    35101 actgaaggcc agatgcgctt gatttctgcg gtaatgggcg gacgtacttt taaaggccgt
    35161 gaagccgaaa gtaaaaaact gctaacctgg ggcttccgtt tctttgaaac cgttaaccca
    35221 ctgaaagtag gtaaagagtt cgcctctgaa ccggtttggt ttggtgattc tgatcgcgct
    35281 tcgttagggg ttgataaaga cgtgtacctg accattccgc gtggtcgcat gaaagatctg
    35341 aaagccagct atgtgctgaa cagcagtgaa ttgcatgcgc cgctgcaaaa gaatcaggtc
    35401 gtcggaacta tcaacttcca gcttgatggc aaaacgatcg agcaacgccc gctggttgtg
    35461 ttgcaagaaa tcccggaagg taacttcttc ggcaaaatca ttgattacat taaattaatg
    35521 ttccatcact ggtttggtta aaaattaaac acttgaaagt gtaatttccg tccccatata
    35581 ctaagcatca gtaaaaaact cccgccttct ggcgggagtt gctatttaat tacgttacgc
    35641 cggagctgac atgaaaacca aacttaacga actgcttgaa ttccctactc cttttactta
    35701 caaagttatg gggcaggcgt tacctgagct ggttgatcag gtggttgaag tggtacagcg
    35761 ccatgcgcca ggtgactaca ccccaacggt aaaaccaagc agcaaaggca actaccactc
    35821 ggtatctatc actatcaacg ccactcatat cgagcaggtt gaaacactgt atgaagaact
    35881 gggcaaaatc gatattgtcc gcatggttct gtaactcgct tctccgttac ccggctcctg
    35941 gtcgggtaac tcccctctcc tcgctgtgat atacttttcc cccactttta ctcattctcc
    36001 acggagatgc cgttttgtat caggataaaa ttcttgtccg ccagctcggt cttcagcctt
    36061 acgagccaat ctcccaggct atgcatgaat tcaccgatac ccgcgatgat agtacccttg
    36121 atgaaatctg gctggtcgag cactatccgg tattcaccca aggtcaggca ggaaaagcgg
    36181 agcacatttt aatgccgggt gatattccgg tgatccagag cgatcgcggt gggcaggtga
    36241 cttatcacgg gccggggcaa caggtgatgt atgtgttgct taacctgaaa cgccgtaaac
    36301 tcggtgtgcg tgaactggtg accttgcttg agcaaacagt ggtgaatacc ctggctgaac
    36361 tgggtataga agcgcatcct cgggctgacg cgccaggtgt ctatgttggg gaaaagaaaa
    36421 tttgctcact gggtttacgt attcgacgcg gttgttcatt ccacggtctg gcattaaacg
    36481 tcaatatgga tctttcacca tttttacgta ttaatccttg tgggtatgcc ggaatggaaa
    36541 tggctaaaat atcacaatgg aaacccgaag cgacgactaa taatattgct ccacgtttac
    36601 tggaaaatat tttagcgcta ctaaacaatc cggacttcga atatattacc gcttaattcc
    36661 atacatcaat ggcccaattt acactgggtc attactcata atatctgcta atgctttaca
    36721 tctccttcgc gtttgtatat tttctttatc acttgcagaa atgcggtgcc acgccttgct
    36781 ccgtaactca ccccattgat taacctattg aaatagttga ttatggtgag caaaagcgtt
    36841 ccgttccaat tagacataag attattgtaa ttttttaaat attatttttc catgaataaa
    36901 attggagtaa gtgcgtggat agtaataatc aaattgaacc ctgtttaagc agaaagtcgt
    36961 cagaaggtaa accacaaata tttacaacct tacgaaatat tgatcttaac cttctgacta
    37021 tttttgaagc tgtatatgta cataaaggga tcgttaatgc agcgaaagtg cttaatctga
    37081 ccccctcggc aatcagtcag tctattcaga aactgcgcgt tatattccct gacccattgt
    37141 ttattcgcaa aggccagggt gtcactccta ccgcatttgc gatgcatcta catgagtata
    37201 tcagtcaggg ccttgagtcc attcttggcg cgctggatat cgaaggaagc tatgataagc
    37261 aacgaacgat aactattgcg accactccct cggtcggagc actggtcctt cctgtcatct
    37321 atcgggcgat taaaactcac tatccgcagc ttttactgcg caacccgccc atcagcgacg
    37381 cggaaaacca actcagtcag tttcaaaccg atctcatcat cgataacatg ttttgcacca
    37441 atcgtacggt gcaacatcat gttctgttca ccgacaatat ggtgttaatt tgccgcgagg
    37501 gaaatccact actctcttta gaagatgaca gagagactat cgacaacgct gcgcatgtac
    37561 ttctgttacc ggaagagcaa aatttcagcg gtctgcggca gagagttcaa gaaatgtttc
    37621 cggaccggca aatcaatttc accagctaca acattttgac aatcgctgca ctggttgcca
    37681 acagtgacat gttagcgatt attcccagcc gtttttataa cctgtttagc cgctgctggc
    37741 cgctggaaaa actgcctttt ccgtccttaa atgaggagca aatagatttc tctatccact
    37801 acaacaaatt cagcctgcgt gatcccatcc tgcacggagt aatagatgtt atccgtaatg
    37861 cattttgaaa aagtattgtt acagccagat cacagcgcag aacgataaaa tggcacaatc
    37921 caacaacaat tttacatttt cgcgaccgct ttggctgctt tcaggtccgt ttcaatgata
    37981 tactgccagt cgttaattca aaaatagttg ataattacaa caatctattg aattgaaacg
    38041 ctttccttcg taattcgcaa ctggaacacg cacgctatga gtaaacccat tgtgatggaa
    38101 cgcggtgtta aataccgcga tgccgataag atggccctta tcccggttaa aaacgtggca
    38161 acagagcgcg aagccctgct gcgcaagccg gaatggatga aaatcaagct tccagcggac
    38221 tctacacgta tccagggcat caaagccgca atgcgcaaaa atggcctgca ttctgtctgc
    38281 gaggaagcct cctgccctaa cctggcggaa tgcttcaacc acggcacagc aacgtttatg
    38341 atcctcggcg ctatttgtac ccgccgttgt ccgttctgtg atgttgccca cggtcgcccg
    38401 gtagctcctg atgccaatga accagtgaaa ctggcgcaga ccattgccga tatggcgctg
    38461 cgttatgtgg ttatcacctc cgttgaccgt gatgacctgc gcgatggcgg tgcccagcac
    38521 tttgcggatt gcattactgc cattcgggaa aaaagcccgc aaatcaaaat tgaaactctg
    38581 gtgccggatt tccgcggtcg tatggatcgt gctctggata ttctgactgc aacgccacca
    38641 gatgtgttca accataacct ggaaaacgta ccgcgtattt accgtcaggt acggcctggt
    38701 gcagattaca actggtcgct gaagctgctg gaacgcttta aagaagcgca tccggaaatc
    38761 ccgaccaagt ctggtctgat ggtgggactg ggtgaaacca atgaagaaat tattgaggta
    38821 atgcgcgacc tgcgccgtca tggtgtgacg atgttaacgc tggggcaata tttgcagcca
    38881 agccgccatc acctgccggt tcaacgttac gttagcccgg atgagttcga cgaaatgaaa
    38941 gccgaagcgc tggcgatggg ctttacccat gctgcatgcg gtccgtttgt ccgctcttct
    39001 taccacgccg atttgcaggc gaaagggatg gaagttaagt aatcctgtaa taattactta
    39061 catctgtctg ataaaaaacc cgctttttga agcgggtttt ttgtatcgaa caagatattg
    39121 agggagcgtc ttgctcgcca cgtcactctt tatgagagag cttttcagcc tgaagatcaa
    39181 cgtctgcgcc ttttttcgcc gcagcatcgt catcattcat cgccttcttg aaccctttaa
    39241 tggccgctcc aaggtctccg cccagcgtac gtaacttctt agtcccaaac agcagaacga
    39301 ccagcgccgc aactaccagc agtttggtaa tactaatctc acccatagat accttcttga
    39361 catataaccg gcaacagaac gcgccttaaa aaccagagaa tattaacggt cattcgacgc
    39421 gcgcacacaa tagcaatctg taacaaggtg aatcaagcgc cgagtaaaaa aacatcataa
    39481 taattgcggc ggcgcaaagc gacggttgtt taagacgggc agttgcgcgc gcacctgacg
    39541 cacacgttcg ggcgtcactt ccgccataat gagtgcaggc atttctgacg ctgccgcaat
    39601 ggtgacgcca aagggatcta taatccggct ttgaccgata tttttgttcc cgcactcccc
    39661 cgccgccacc atataacagg tggtatccag cgcacgagcg gcaagcaacg ttgaccagtg
    39721 atgctctttg agcggcccgc gaacccaggc ggcaggaagt accaggattt cagctccctg
    39781 taatgcctgt gccagcgcca gctctggaaa gcgtaagtca taacaggtca tcagaccgac
    39841 cttcatccct tccacctcca gtaacggagc gatttcatta ccagcatcaa cacggcgtga
    39901 ttcctgaatg gcaaatgcat catagagatg cagtttggca taacgggcga cgatgtttcc
    39961 tgcctgaagt gccaccagca tattccatgc gcgccccggc gttgaaggaa catgaatcgt
    40021 cagaattgtc gtcatcatgt tacgtttact ttctcgccgt aaagtccgag gaattcgcct
    40081 tccagcagct gtgctgattt aaccgataga tctgcatcat gatcatcgcg cgccagcaat
    40141 gcttccggca ggacaaacag cgatacgtcg ttttccgccg cctgcgccat caacgaggca
    40201 caaatctcag cgttcttttc ccacacagat gtaacagcaa actgtcctgc ggcaaccagc
    40261 attgccacct cctgtcagag tcgtaaaatt cgccaacgac gattattcgg cgttacactt
    40321 atcactcata caaatcaaat agcaggattt tgcagtgtta caacttcttt tagcagtttt
    40381 tattggcggt ggtacgggaa gcgtggcgag atggctgtta agtatgcgat ttaacccact
    40441 gcatcaggcg attccgttgg ggacgctgac agcaaacctg attggggcat tcatcatagg
    40501 aataggattc gcatggttca gcaggatgac gaacattgat ccagtgtgga aagtattaat
    40561 caccaccgga ttttgtggcg gtctaacaac cttctcaaca ttttcggcag aagtggtgtt
    40621 tttgttacaa gagggccgct ttggctgggc attactgaac gttttcgtca accttctggg
    40681 gtcttttgcc atgaccgcac tggcattctg gctgttttcg gcctcaaccg cacactaaag
    40741 accaaaaaaa acccgctgat taagcgggtt ttgaattctt gctgacgtat cttacagagc
    40801 gattacgttt gcagcagaag ggcctttggc accgttagtg atttcgaact ctacgcgctg
    40861 accttcagca agagttttaa aaccattagt ctggattgca gagaagtgta cgaacacgtc
    40921 tttgctgccg tcttccggag taatgaaacc gaatcctttg gactcattaa accacttaac
    40981 gttaccttta atcttagaca tcaaaattac ctttacatga aaaatagaca caaatgctgt
    41041 gtcggttacc agtacaccaa ttgtggtacg ctttgtccag tgtaacttta ctaaaaagtg
    41101 ataaaagtcg cgttattttt gatgttactt attttagcta ttgattttaa agaagttact
    41161 aaaacttcat ttgtctcaaa actgaaagcg catccaggca aagtacacat tgccattgtt
    41221 gtaggtaccc ggaatgtagg tcatctgaaa agtcactggg ccataaccca cggaggccaa
    41281 tggcagtaga accgggagag ggatgtaatt ccagttatcg cgtgccgtta cgccagcggt
    41341 gaatcccaga cctaaatgaa aattttcatc cgccagcggt cgccaggtac tttcccatcc
    41401 gtatccggca atcggttccc atttgttcca cgagtcctta aatgccatgg catacaggcc
    41461 atgccagttt cctttttcat cccaacgcga caggccaaaa ccgccacccc acggtcgctc
    41521 gttatagcga tcggtttttt ctttgtcgta agcgaaacgt gcatgccagg tgatggcagg
    41581 aatatataaa tcataatgtt caggctgttg ccaggtttgt gcaatatttt ctctaaacgt
    41641 tgtcatccac tcatctgcgt tagcaaaaac tttaccaacg ctgattaact gaataaaaac
    41701 aaaggaaaag atagcgacat atttactcac gttcatttgt gaccataaaa catttatcaa
    41761 aaatctacta ctagcatagc aaagctacaa ttaacataac cttaatagac ccaacataaa
    41821 gaataatctg aatagctgct ctatttattt ccgcttgttc aagttaaata tttccgcgca
    41881 tcgattaaag atgatgcgtc gttttctgcg atgggaatag tcaaaaaaga aaaaccaagt
    41941 cttttttgat gacaaaatgc aatcaaggaa aaattatttt attttttaac gagatacaac
    42001 aatcatctta acgaagtata taatatatat cgtcaaccta tgctcatatt agattatttt
    42061 ttgagcgcac agccgcagct aacaccattg caattaacaa atttgcatca atccaccatc
    42121 aatttgcaca cattattatg tgataattgc caaccgctaa atatgcgttt tgttatctat
    42181 gtataaaaac agcaacttca atgtcttaat ggcagttttt cttgatttta atcagcattc
    42241 atcgccaatt tattgggcat attttttcct taagctttag gaatttttta ttatttactt
    42301 tggggcctgg agacaggaaa aattatgctg acattcattg agctccttat tggggttgtg
    42361 gttattgtgg gtgtagctcg ctacatcatt aaagggtatt ccgccactgg tgtgttattt
    42421 gtcggtggcc tgttattgct gattatcagt gccattatgg ggcacaaagt gttaccgtcc
    42481 agccaggctt caacaggcta cagcgccacg gatatcgttg aatacgttaa aatattacta
    42541 atgagccgcg gcggcgacct cggcatgatg attatgatgc tgtgtggatt tgccgcttac
    42601 atgacccata tcggcgcgaa tgatatggtg gtcaagctgg cgtcaaaacc attgcagtat
    42661 attaactccc cttacctgct gatgattgcc gcctattttg tcgcctgtct gatgtctctg
    42721 gccgtctctt ccgcaaccgg tctgggtgtt ttgctgatgg caaccctatt tccggtgatg
    42781 gtaaacgttg gtatcagtcg tggcgcagct gctgccattt gtgcctcccc ggcggcgatt
    42841 attctcgcac cgacttcagg ggatgtggtg ctggcggcgc aagcttccga aatgtcgctg
    42901 attgacttcg ccttcaaaac gacgctgcct atctcaattg ctgcaattat cggcatggcg
    42961 atcgcccact tcttctggca acgttatctg gataaaaaag agcacatctc tcatgaaatg
    43021 ttagatgtca gtgaaatcac caccactgct cctgcgtttt atgccatttt gccgttcacg
    43081 ccgatcatcg gtgtactgat ttttgacggt aaatggggtc cgcaattaca catcatcact
    43141 attctggtga tttgtatgct gattgcctcc attctggagt tcctccgcag ctttaatacc
    43201 cagaaagttt tctctggtct ggaagtggct tatcgcggga tggcagatgc gtttgctaac
    43261 gtggtgatgc tgctggttgc cgctggggta ttcgctcagg ggcttagcac catcggcttt
    43321 attcaaagtc tgatttctat cgctacctcg tttggttcgg cgagtatcat cctgatgctg
    43381 gtattggtga ttctgacaat gctggcggca gtcacgaccg gttcaggcaa tgcgccgttt
    43441 tatgcgtttg ttgagatgat cccgaaactg gcgcactctt ccggcattaa cccggcgtat
    43501 ttgactatcc cgatgctgca ggcgtcaaac cttggccgta ccctttcgcc cgtttctggc
    43561 gtagtcgttg cggttgccgg gatggcgaag atctcgccgt ttgaagtcgt aaaacgcacc
    43621 tcggtaccgg tgcttgttgg tttggtgatt gttatcgttg ctacagagct gatggtgcca
    43681 ggaacggcag cagcggtcac aggcaagtaa atagtaatgc cggaggcaag tttcctccgg
    43741 ctttatcatg tcacccactg tggtatatgc gttgtggtct gccaactttg ccgtgaacaa
    43801 tttcagcaat aatcagatgg cggctggcgc aatattcaag ataacgcctg gcagtggtgc
    43861 ggctgatggt cagtgcctgc gccaccgttt ctgccgtatg ttgcacacca ggctctttaa
    43921 acagttttcg caccgcgttt agcgtcaagg ggtcaatacc ggtcggtagc tcgtccttag
    43981 gttcaccgcg agcataagca ttaaacatct catcaatttg cttctggctg gcgctatcaa
    44041 tactttccag catatgttta cgctggcgga aacgggttag cgtttgcccc agccgttcat
    44101 aggcaatggg cttaatgaga taatcaaata caccacaacg tacggcttca gacaccgttt
    44161 ccatatcgct ggctgcagtg gtaaacacca cgtcgccggg ataatgcgcc tgcaccagtt
    44221 catgcagtaa attaatccct ctaccgtcag gaagatagtt atcgagcaag attagccccg
    44281 gcttaaaacg ctcgatcatc attcgggcct gcgccagatt tcccgccagt aatatctgac
    44341 tgaatccggg aatgtgacga atatattccg catgcatctc tgccagcggc gtttcgtcct
    44401 caacgatcaa tagggttaat ggagctgtca ttaggtttca ctttcggaat atagattgaa
    44461 aataaggtac cgcagggatc attatcttcg agagtgataa caccaccgca gcgcgttacg
    44521 tagctggcaa tcaagtacaa cccaatgcca tgttcaccgg gctcgtcagc acgcgtactg
    44581 accccctgct caaatatttt gtctcgtaga gactctggaa cgccgcagcc ctgatcggcg
    44641 acttcaatca ccacatcatc gccttcatcg ctgaggaata attcaacgat cttgtttcct
    44701 tcatcgctac gcaggctggc ttcgaaggcg ttatcaagta aattgcccac aatggctgca
    44761 aactcggtgc tatccagtcc tggcggcagt tgcgaaagct ggctaccggg gacaatgatc
    44821 atttttagcc ccagttcccg ggcgcgctgc actttaccaa aaagcagccc cgccacctgg
    44881 cgatcggcaa acgcctcgcg caggctgtca ataagctgtt gctgggcctg agactccccc
    44941 tgcaccatcg ccagcacgcg atcatactct ttcatctgca acagaccatt gagcgtcgac
    45001 atccaattga gatgctcgtg tcgcaatgta cgaaggctct caacgtattg ttttatttgc
    45061 gtcagttgcg cattgagggt ggaaatttcg tctttactac gaaagctgat aatggccccc
    45121 agcaaatcat cacctgaacg aatagcttcc cggttggcaa taacgctcag accgttaaag
    45181 ttcgccacca catcctgacg tttttcatca atctgttcgg taaagaaatc ggcgggcctg
    45241 accacttcaa caatgggttt acccaaccat tgccgtccgg gggaactcag ccccagcatc
    45301 tttcttgcgt tacgattgat ggcggtaatg taaccatgcg gatccaccgc aatcagccct
    45361 tcataaaccg aactaaacag cgcctcttgc tgacggacca cgcgtgcgat ttgctttggc
    45421 tccatgccca tcatctgccg acggatatgc gcggccagga accacgacag caacatcaga
    45481 atccctaaca gcacgacaaa cacacctgcc atcggtaata aaaactcagc ccgccagcta
    45541 tcgattttac tcaccaggta gccaatcgac accacgccga tgacttttcc atcgtcatca
    45601 aagattggcg ttttggcgcg catcgccatc cccattgacc ctttcccggt aatgaagtag
    45661 ctctcccctt tctccagcgc gccctgtttg gtgaactgca taggataacc aattttctcc
    45721 ggattaggat ggtaaaggcg gatcgagtgc cggtccccaa tcaccacata atcaaaatcg
    45781 gtatctcttt gtaatttgtt agcgatggtc gccagccgtt tgtagtcacg cgttttcacc
    45841 gcagagatga cactgtcatt ggaggcaata attttcgcct gattcattgc catgtcgcgt
    45901 acatgaagcg ttaaatagtc ctcaaaactg gccgtaaaat attgcgccag ggctgcaatg
    45961 acaaatattg agaacaccag aatcagcaaa aagatacgca gcggaaatgc cagtctttgg
    46021 aaaaatgcaa actgtttatt ctcgttaagc tgcaacattg ttttccttgc gggttgtccc
    46081 gagcctcttt gacggatgta attaaaatgt tgaatcaaaa tacatagata ttaattatga
    46141 tcgtggcaaa ttttattcat taaatcaatt aaatcactta aacctgcgag tcatttcgta
    46201 attacattaa ttaaaaaact taaaatcatt aaataaataa aaaaccacta actctatgtg
    46261 aaataaatca aaatttcacg ccgaaatact ccttaggatg tatagcgaaa ggagaaaaag
    46321 atatacctcg atcaccccct ttctcccaag tgaaaataaa aggttatcag tttgcaacat
    46381 tgaacaacat tcgttgcaaa tcgataacaa catgcacctt caggatacta tttattatgt
    46441 tcggcaatga tattttcacc cgcgtaaaac gttcagaaaa taaaaaaatg gcggaaatcg
    46501 cccaattcct gcatgaaaat gatttgagcg ttgacaccac agtcgaagta tttattaccg
    46561 taacccgcga tgaaaagctt atcgcgtgcg gtggaattgc cggaaatatt attaaatgcg
    46621 ttgctatcag tgaatccgtc cgcggtgaag gactggcgct gacattagcc actgaattga
    46681 taaacctcgc ctatgagcgg cacagcacgc atctgtttat ttataccaaa accgaatacg
    46741 aggcgctgtt ccgccagtgc ggtttttcca cgctgaccag cgtacccggc gtgatggtgc
    46801 tgatggaaaa cagcgccacg cgactgaaac gctatgccga atcgctgaaa aaatttcgtc
    46861 atccagggaa caagattggc tgcattgtga tgaacgccaa tccctttacg aatggtcacc
    46921 gttatctgat tcaacaggct gcggcacagt gcgactggtt gcatctgttt ttagtcaaag
    46981 aagattcttc acgcttcccc tatgaagacc ggctggattt ggtgttaaaa ggcaccgccg
    47041 atattccacg cctgactgtg catcgtggct ccgaatacat catctcccgc gctacgttcc
    47101 cttgctactt cattaaagaa cagagcgtca ttaaccattg ttacaccgaa attgatctga
    47161 agattttccg tcagtacctc gctcccgcgc tgggtgtaac tcaccgcttt gtcggtactg
    47221 aacccttttg tcgcgttacc gcccagtaca accaggatat gcgctactgg ctggaaacgc
    47281 cgactatctc cgcaccgccc atcgaactgg ttgaaattga gcggctgcgt taccaggaga
    47341 tgccgatatc cgcttcccgg gtacgtcaac tgctggcgaa aaacgatctc acggctatcg
    47401 cgccgctggt ccctgcagtc acgctgcatt atttgcagaa cctgcttgag cactcccgcc
    47461 aggacgcggc agctcgtcaa aagacccccg catgagaaac aggtgaaaaa tgaaaataaa
    47521 ccagcccgcc gttgcaggca cccttgagtc tggggatgtg atgatacgca tcgccccact
    47581 cgatacgcag gatatcgacc tgcaaatcaa tagcagcgtt gagaaacagt ttggcgatgc
    47641 aattcgcacc accattctgg acgttctcgc ccgctacaac gtgcgcggcg tacagctgaa
    47701 tgtcgatgac aaaggcgcac tggactgcat tttacgtgca cgactggaag ccctgctggc
    47761 acgcgccagc ggtatcccgg ctctgccatg ggaggattgc caatgatttc cgcttcgctg
    47821 caacaacgta aaactcgcac ccgccgcagc atgttgtttg tgcctggtgc caatgccgcg
    47881 atggtcagca actccttcat ctacccggct gatgccctga tgtttgacct cgaagactcc
    47941 gtagcattgc gtgaaaaaga caccgcccgc cgcatggttt accacgcgct gcaacatccg
    48001 ctgtatcgcg atattgaaac cattgtgcgt gtcaacgcgc tggattccga atggggtgtt
    48061 aacgacctgg aagccgtcgt tcgcggtggt gcggacgttg tgcgtctgcc gaaaaccgat
    48121 accgctcagg atgttctgga tattgaaaaa gagatcctgc gtatcgaaaa agcctgtggt
    48181 cgtgaacccg gcagcaccgg cctgctggcg gcgattgaat ctccgctggg gattacccgc
    48241 gcagtggaaa tcgctcacgc ttccgagcgt ttgatcggta tcgccctcgg tgcagaagac
    48301 tatgtgcgca acctgcgtac agaacgctcc ccggaaggaa ctgaactgct gttcgcacgc
    48361 tgttccattt tgcaggccgc gcgctctgcg ggtattcagg cgttcgatac cgtctattcc
    48421 gacgctaaca acgaagccgg atttctgcaa gaagccgccc acatcaaaca gctgggcttt
    48481 gacggcaaat cgctgatcaa cccgcgtcag attgatctgc tgcacaacct ctacgcaccg
    48541 acccagaaag aagtggatca cgcccgccgc gtcgtagaag ccgctgaagc cgccgctcgc
    48601 gaaggcctcg gcgtggtttc cctgaacggc aagatggtgg acggtccggt tatcgatcgc
    48661 gcccgtctgg tgctctcccg tgcagaactt tccggcatcc gcgaagaata aggcaatcaa
    48721 aatgacgcag aaaattgaac aatctcaacg acaagaacgg gtagcggcct ggaatcgtcg
    48781 cgctgaatgc gatcttgccg ctttccagaa ctcgccaaag caaacctacc aggctgaaaa
    48841 agcgcgcgat cgcaaactgt gcgccaacct ggaagaagcg attcgtcgct ctggtttaca
    48901 ggacggcatg acggtttcct tccatcacgc tttccgtggc ggtgacctga ccgtcaatat
    48961 ggtgatggac gtcatcgcga agatgggctt taaaaacctg accctggcgt ccagctccct
    49021 gagtgattgc catgcgccgc tggtagaaca cattcgccag ggcgtggtta cccgcattta
    49081 tacctccggc ctgcgtggtc cactggcgga agagatctcc cgtggtctgc tggcagaacc
    49141 ggtgcagatc cactctcacg gcggtcgtgt gcatctggta cagagcggcg aactgaatat
    49201 cgacgtggct ttcctcggcg tcccgtcctg tgatgaattc ggtaatgcca acggctacac
    49261 cggtaaagcc tgctgcggct ccctcggcta tgcaatggtt gatgccgaca acgcaaaaca
    49321 ggtcgtgatg cttaccgaag aactgctgcc ttatccgcat aatccggcaa gcattgagca
    49381 agatcaggtt gatttgatcg tcaaagttga ccgcgttggc gatgctgcaa aaatcggcgc
    49441 tggcgcgacc cgtatgacca ctaacccgcg cgaactgctt attgcccgta gcgctgcgga
    49501 tgtgattgtc aactctggct acttcaaaga aggtttctcc atgcaaaccg gcaccggcgg
    49561 cgcatcgctg gcggtaaccc gtttcctgga agacaaaatg cgtagccgcg atattcgcgc
    49621 cgacttcgcc cttggcggta ttaccgcgac gatggttgac ctgcacgaaa aaggtctgat
    49681 ccgcaaactg ctggatgtgc agagctttga cagccatgct gcgcaatcgc tggcccgtaa
    49741 ccccaatcac atcgaaatca gcgccaacca gtacgctaac tggggttcga aaggcgcatc
    49801 ggttgatcgt ctcgacgtgg tggtactgag cgcgctggaa attgacaccc agttcaacgt
    49861 taacgtgctg accggctctg acggcgtact gcgtggtgct tccggtggtc actgcgatac
    49921 cgcgattgcc tctgcgcttt ccatcatcgt cgcgccgctg gtacgcggtc gtattccgac
    49981 tctggtggat aacgtactga cctgcatcac cccaggctcc agtgtcgata ttctggtcac
    50041 agaccacggt atcgcagtta acccggcacg tccggaactg gcagaacgtc tgcaggaagc
    50101 gggcattaaa gtggtttcca ttgagtggct gcgcgaacgt gcgcgtctgc tgaccggtga
    50161 accacagccg attgaattca cagaccgcgt cgttgccgtt gtgcgttacc gcgatggctc
    50221 ggtgatcgat gttgtgcatc aggtgaagga ataagccatg cacctgcttc ctgaactcgc
    50281 cagccaccat gcggtatcaa ttcccgagct gctcgtcagc cgggatgaaa ggcaagcacg
    50341 gcaacacgtc tggctcaagc gccatcctgt tccactggtc tcctttaccg tggttgcgcc
    50401 tgggccgatt aaagacagcg aggtcacacg ccgaattttt aatcatggcg tgacagcctt
    50461 gcgtgcctta gccgcaaaac agggctggca aattcaggag caggctgcac tggtttccgc
    50521 cagcgggccg gagggcatgt tgagcattgc cgccccggct cgcgacctca agctcgccac
    50581 cattgagctt gaacatagtc atcctctcgg gcggttatgg gatatcgatg tcctgacgcc
    50641 cgaaggcgaa attctctccc gccgcgacta ttcactgccg cctcgccgct gcctgttgtg
    50701 cgagcaaagc gcagccgtct gcgcgcgtgg aaaaacccat caactgaccg atttactcaa
    50761 ccgcatggag gcactgctga acgatgtcga tgcctgcaac gtcaactaaa accacaaagc
    50821 ttgcgacgtc attaatcgat gagtacgccc tgctgggctg gcgcgccatg ctgactgaag
    50881 tcaatctgtc accgaaacca ggcctcgtgg atcgcattaa ctgcggtgcg cacaaagata
    50941 tggcgctgga agatttccac cgcagcgcgc tggcgattca gggctggcta ccccgtttca
    51001 ttgaatttgg tgcctgtagt gcggaaatgg caccagaagc ggtactccac ggattacgcc
    51061 caattggtat ggcttgcgaa ggtgatatgt tccgcgccac tgcgggcgta aacacgcata
    51121 aaggcagcat tttttcttta gggctgctat gtgcggcaat tggccgtttg cttcaactca
    51181 accaaccggt aacgccaaca accgtttgtt ctacggcggc aagtttctgc cgtggcctga
    51241 ccgatcgcga actgcgtacc aataattcac aactgacggc aggtcaacgg ttgtaccaac
    51301 agcttggcct taccggcgca cgcggtgaag ccgaagcggg ttatccactg gtgatcaatc
    51361 acgccttgcc gcattacctc actctgctgg atcaggggtt agatcctgaa ctggcattgc
    51421 tcgatacctt gctcctactg atggcgatca acggcgatac caacgttgca tcgcgcggtg
    51481 gcgagggggg cctgcgctgg ctacagcgcg aggcgcaaac attattgcaa aaagggggca
    51541 ttcgaacccc cgccgatctc gattatctcc ggcagttcga cagggagtgt atcgaacgaa
    51601 atctcagtcc aggcggcagt gctgacctac tgatccttac ctggttttta gcacagattt
    51661 aattatttaa gcacttgata aatttggaaa tattaatttt cggagaaccc gtatgtcttt
    51721 agcaaaagat aatatatgga aactattggc cccactggtg gtgatgggtg tcatgtttct
    51781 tatccctgtc cccgacggta tgccgccgca ggcatggcat tacttcgctg tgtttgtggc
    51841 aatgattgtc ggcatgatcc tcgagccaat tccggcaaca gcgatcagtt ttattgcggt
    51901 tactatttgc gttattggca gtaattacct gctctttgat gccaaagaat tagctgaccc
    51961 agcgtttaat gcgcaaaaac aggcgctgaa atggggcctg gctggttttt ccagcaccac
    52021 ggtatggctg gtatttggcg catttatttt tgcattaggg tatgaagttt ccgggttagg
    52081 tcgtcgcatt gcccttttcc tggtgaaatt catgggcaaa cgcacgctga cgttgggtta
    52141 tgcgattgtc attatcgaca ttctgctggc accgtttaca ccttccaaca ccgcgcgtac
    52201 cgggggtacg gtttttccgg tcattaaaaa cctgccgccg ttgtttaaat cattcccgaa
    52261 cgatccgtcc gcgcgtcgta ttggcggcta tttgatgtgg atgatggtca ttagtaccag
    52321 tctgagttcg tccatgtttg tcaccggtgc ggcaccaaac gtgctgggtc tggagttcgt
    52381 cagcaaaatt gccggtatcc agattagctg gttgcagtgg ttcctctgct tcctgccggt
    52441 tggggttatc ttgcttatca ttgcgccgtg gctttcctac gtgctgtaca aaccggaaat
    52501 cacacacagt gaagaagtgg caacctgggc gggtgatgaa ctgaaaacca tgggtgcgct
    52561 gacacgcaga gagtggacac tgattggcct tgtattgctc agcttaggtt tgtgggtatt
    52621 tggcagtgaa gtcattaatg ctactgcggt tggtctgctg gcagtttcgc taatgctggc
    52681 cctgcacgtt gtgccttgga aagacattac ccgctataac agcgcatgga acacactggt
    52741 caacctggca actctggttg tgatggctaa cggcctgact cgttctggtt ttattgactg
    52801 gttcgccggt accatgagta cgcacctgga aggattctca ccaaacgcaa cggtgattgt
    52861 actggttctg gtgttctact ttgcacacta cctgtttgcc agcctgtctg cgcacaccgc
    52921 aaccatgctg ccggttattc tggccgtcgg taaaggtatt ccgggcgtac caatggaaca
    52981 actgtgtatc ctgctggtgc tgtctatcgg tatcatgggc tgtctgacgc cgtatgcaac
    53041 cggtccaggg gtgattattt acggctgtgg ctatgtgaaa tcaaaagatt actggcgtct
    53101 tggcgcaatc ttcggggtga tttacatctc tatgttgctg ttggttggct ggccgattct
    53161 cgccatgtgg aactaatacg ttcgccaaac gctgaataaa tcatcacgcc cgccaggtaa
    53221 gcccacctgg cgggcttttt tatgatttaa tagatagtat tcagtgtatg tatgagttcc
    53281 acacccatta tgaaagcatt ctggcgtaac gccgcgttgc tcgcggtttc tctgcttccc
    53341 ttctcttctg ccaacgcctt agcgttgcag gcaaaacagt atggcgattt tgatcgctat
    53401 gtcctggccc tctcctggca aaccggattt tgccagagtc aacacgatcg aaatcgtaac
    53461 gaacgagatg aatgtcgcct gcaaaccgaa acgaccaaca aagctgattt tctgaccgta
    53521 catggtctgt ggccaggatt gcctaaatcg gttgctgccc gtggtgttga tgaacgccgc
    53581 tggatgcgct tcggttgcgc tactcgccca atcccgaatc taccagaagc gcgcgccagc
    53641 cgaatgtgtt catcgccgga aaccggatta tcactggaaa cggccgctaa actaagtgaa
    53701 gtcatgccag gagctggcgg acgttcctgc ctggaacgct acgaatatgc caaacacggt
    53761 gcctgctttg gttttgatcc ggacgcatac ttcggtacga tggtacgcct gaatcaagaa
    53821 attaaagaga gcgaagccgg aaaattcctt gcggataatt acggtaaaac agtgagccgc
    53881 cgtgactttg acgccgcctt tgccaaaagc tggggaaaag agaacgtgaa agcagttaag
    53941 ctaacgtgcc agggtaaccc tgcgtatttg actgaaattc agatctcgat caaagctgac
    54001 gccatcaacg ctccgctttc tgcaaactca ttcttgccac aacctcaccc aggtaactgt
    54061 ggcaaaacct ttgtgattga taaagcgggt tattaatcat ctgatttaca aaacacgcta
    54121 attcgtcttc cataaaccaa ggcgattaag atttatacat aatgcgctgc attgaggaat
    54181 tccctgaatg tgacgcaaat cacttcaaag agtgagcaac agtcagtatc atcatgtgag
    54241 ttaaaccctc gccgcctgac ggtgagggtt ttcttttggg tatgtttatc tgcgacactc
    54301 gcagcaccga cgacatggag taaaaatgtc cagaccaact atcatcatta acgacctgga
    54361 tgccgaacgc atcgatattc tgctggagca acccgcctat gctggtttgc caatcgccga
    54421 cgcgttaaac gcagagttgg atcgcgccca aatgtgttcg ccagaagaga tgccacacga
    54481 cgtggtgaca atgaacagcc gggttaaatt ccgcaatctt agcgatggcg aagtgcgtgt
    54541 gcgcacgctg gtgtatccgg caaaaatgac cgatagcaat actcagcttt ccgttatggc
    54601 tccggtaggt gccgcactgc tggggctgcg cgttggcgat tccattcact gggaacttcc
    54661 gggcggcgtt gcaacccacc ttgaagtgct ggaactcgaa taccagccag aagctgctgg
    54721 cgactacctg ctttaatccc atctgcacaa gcgataactc gctttgccca gaggatgcac
    54781 tcgcatcctc tttacgcaaa atcagcaatt tttcctggtt ctcactgttc acttttgctg
    54841 caaaattatt ccgtttcgtt tgtgggaata accatggcag aagcatttta catcctgata
    54901 ggatttctga ttatggcggc gattatcgtc atggctgtcc tttacctcga aaaccactcc
    54961 tgacgatcat attgttcccc ccggcatcgc attcaccaga cctgaaaccg ccttctgcgc
    55021 cgcctctgcg ctttgtgcac cgggtaccag aatcacctta cggcactcct cttcacgttt
    55081 ttcgaaaatc tcatatcccc gggcggcctc ttcaaacggc atatagtggg taacaatttc
    55141 ttctggtttc agtaatcctt tctcaattaa cggtaataat tctcccagcc atgcgtgaac
    55201 gtgggtctgt cccattttaa acgacaaccc tttatcaaag gcgtcgccaa acaggaaacc
    55261 gtgaataaat ccagcgtaga cgcccggtac gctaacaatg ccgccacgcc tgaccgccgc
    55321 aatacactga cgcaacgctt taccgctgct gccctccagt ttcaggttag tcagcaccgt
    55381 ttccgtggtg ctgcctttcg cttcaaaacc gacggcgtct attactgcat ccacgccccg
    55441 gtgacctgcc gtttgttcaa taattgactg tgccggatcg ctgtcttcat caaaattaat
    55501 cgggatcgcg ccgtagcggt cggcggcgaa atgcaagcgg tagggatgat gatcaacaac
    55561 aaaaatctgt tccgcaccga gcaaccgtgc acaggcgatt gtcaacaatc ccacaggacc
    55621 agcaccatag actgcaacgc ttgaaccttg ttggatctgc gcattttttg ctgcctgcca
    55681 tgccgttggc agaatatcag aaaggaaaag cgctttatca tctgaaagca aaggcggtac
    55741 tttaaacggc cccacattcc ctttagggac gcggacatat tccgcctgcc caccaggaac
    55801 gccgccatac aggtgactat aaccaaacaa tgccgctgga gctggtatct gttttttatt
    55861 gagcgcagcg cctttacccg cattggtatt ttcgcaggcg gcatattgtt gcaatcgaca
    55921 gaaaaaacag tcgccacaag caatgacgaa cggaattacc actcggtcgc ctttttgcaa
    55981 attttttacg tcctttccgg tttcaactac ttcccccata aattcatgac caaaaatatc
    56041 gccatgttta acctgaggta ttttgcctcg ataaagatgg aggtcagagc cacagatcgc
    56101 cgttgccgta atacgcagaa taatatcatc tgcctgttca acgcccggat cgggaacatt
    56161 ttctacctga acgtgatgtg ggccgtgata agtcaatgct ttcatgcaac ctccagagac
    56221 agttcaaata agagtcagtc tttaagggta gctatcacag cgggaaaacg ggcggtacca
    56281 caggttttgg gagaattcct ggtgttcagt gagaatatat tcatcacaga aacagttcgt
    56341 aaggaaaaag aaccagacaa atatcaggga taaatattat aatcatggcg aatgatttgt
    56401 tcatgattaa cagggagaaa gggttatgta taagacaatc attatgccag ttgatgtatt
    56461 tgaaatggaa ttgagcgaca aagctgttcg ccacgctgaa ttcctcgccc aggatgacgg
    56521 agttattcat ctacttcacg tactacccgg gtcagccagc ctgagcctgc accgttttgc
    56581 cgctgatgtg cgtcgttttg aagagcatct gcaacatgaa gcacaagaac gtctgcaaac
    56641 gatggtcagc cacttcacca tcgatccttc ccgcattaaa caacatgtcc gttttggtag
    56701 cgtgcgggat gaagtcaatg agttggcaga agaactgggg gctgatgttg tagttattgg
    56761 ttctcgcaac ccatcgattt cgacccatct gttaggttct aacgcctcga gcgtgatccg
    56821 ccacgccaat ctgccggtgc tggttgtgcg ttaattgcca gaataagtat cccgccctgc
    56881 ccggagccat cccggcgggg ctttttaatg ccataaaaaa gccgccaggt ttgaccccgg
    56941 cggctaagca attgcaggtg aatcttactt cttcttatgc agttttggtg cgaatcaggt
    57001 agtcaaaagc actcagagag gctttggcac cttcgccagt ggcgatgatg atctgcttgt
    57061 acggaaccgt cgtacagtca cccgctgcga acacgccttt cacgttggtt tcgcatttcg
    57121 catcaatgat aatctcgccc atgcggttac gttcgactgc gccttcgagc cagttggtgt
    57181 tcggcagcag accaatctgg acgaaaatac cggccagttc gatgttgtga atatcgccgc
    57241 tgacacgatc tcgatattcc agaccaacga ctttgctgcc gtcgcctttc acttccgtgg
    57301 tttgcgcatt cagaataatg tcgacgtttt tcaggctgcg cagtttgtcc tgcagaacct
    57361 ggtcggcttt catttctggc gcaaattcca gcagcgttac gtgctcaacg atacccgcca
    57421 ggtcaattgc cgcttccacg ccggagttac cgccgccgat aaccgctacg cgtttacctt
    57481 taaacagcgg gccgtcgcag tgcgggcagt aggtcacgcc tttggtgcga tactgatctt
    57541 cgcccggaac gttcatgttg cgccattttg caccggtcgc cacgataatg ctgcgtgctt
    57601 tcagtaccgc gccagaagct gtttcaatct gatgcagacc accttcaact gctgctggga
    57661 tcagtttgct ggcgctctgg ctgtcgatca catcaacgtc gtattcatca acgtgaactt
    57721 tcagtgcgcc tgccagcttc tgcccttcag tcttcggtac agaaatgtag ttttcgatat
    57781 caacggtatc gaggatctga ccaccaaaac gttcgcccat cagaccggta cggatgcctt
    57841 tacgtgcgga gtaaattgct gccgctgcac ccgccgggcc ggaaccgacg attaatacgt
    57901 cataagcatc acgcttgttc agctcttctg ccgcacgttt ttccgcgcca gtatcaattt
    57961 tggcaacgat ttcagtcaac gtcatgcggc cctgaccaaa ctctttcccg tttacgaaca
    58021 ctgccggaac gcccatcacg ttgcgatcgg tgatttcgtt ctggaaggtg ccgccgtcaa
    58081 ttgcagtgtg cttgatgcgc gggttcagta cgctcatcag gttcagcgcc tgcaccacgt
    58141 ccgggcagtt gtggcaagag agcgagtaat aggtttcgaa ttcaaaatca ccgtcaatat
    58201 ggcgaatctg ctccagcaga gactgcgctt ctttcgacgg atgaccaccg gtccacagca
    58261 acgccagtac cagcgaggtg aactcgtggc ccagcgggga gcctgcaaaa cgtggcccct
    58321 ggttggaacc tgggttggtg atcaggaaag acggcttacg caccggcaag ctgttatctt
    58381 ctttaaaggt gactttgtct gacagttctg cgatttcagc caacagttcc ttgatttctg
    58441 ccgatttagc gctgtcatcc agcgtggcaa ttaactcaac aggcttggtc aatttctcaa
    58501 ggtaagcctt gagttgagtt ttcatatttg tgtcgagcat gtttatctcc tgggctttaa
    58561 acatcatcat gcaagcggcc tctgcggcta cctggatgca gcttgcatca tggtgcgggg
    58621 aagaaaatcg ggtgccgcag cacccgaaga attaggtgaa tttccgaagt atttcgcgtc
    58681 agagcaaggc ggctagcctg tgaatccccg ggagcttaca caagtaagtg accggggtga
    58741 gcgggcgacg ccaacgccgc tatggcgtga aagacgaagg aaatttagat tttaccaacc
    58801 aggtccagag acggagccag agttgcttca ccttctttcc atttagccgg gcaaacttca
    58861 cctgggtgag aagctacgta ctgtgctgct ttgattttac gcagcaggtc agacgcgtca
    58921 cggccaatgc cttcagcggt aacttcgatt gcctggatga taccctgcgg gtcaacaacg
    58981 aaggtcgcac ggtcagccag accttcatct tcacgcatgt tgtcgaagtt acgggtcagg
    59041 gcgccagtcg ggtcgccgat catcgcatat ttgattttag cgatggtttc agagctgctg
    59101 tgccatgctt tgtgggtgaa gtgagtatcg gtagatactg cgtatacgtc tacgcccagt
    59161 ttctgcagtt cttcgtagtg gtcagcaacg tcacccagtt cggtcgggca tacgaaagta
    59221 aagtcagccg ggtagaagaa gaagacgctc cagcggcctt cggtatcttt ttcggtgatt
    59281 tcgatgaatt cgccgttttt gaatgcctgg tttttaaaag gtttaatttt ggtgttaatc
    59341 aaggacatct atacttcctc cgtgttttcg atgagatgta aggtaaccaa tttttgccga
    59401 ttcggctaat gcgtttccat tatcaaatcg ataagtttta ccttacaacc ttcgtaagac
    59461 aactttgtga actttgcacc gccagcggcg ataaaaagta aaatggcccc ctttccaggt
    59521 gaccgtgtaa tctgaactac cctttggtat cttcagtgcc tgcctgcagg ctgaggtgtt
    59581 gcccttacaa atgcaacaac gacatggatt acaacaccct cataaacaaa gggcaatcac
    59641 ctgatctaag ctcttaccta tgacagtgat aggttatgcc ttttactcga cttttgcact
    59701 gactgaaaag gacaaattaa tgttaaaaaa gatactttta ctggctctgc ttcctgcaat
    59761 cgccttcgca gaggaacttc ctgctccagt aaaagcgatt gaaaaacagg gcattacaat
    59821 catcaaaaca ttcgatgccc ccggaggaat gaaaggttat ctcggaaagt atcaggatat
    59881 gggcgtcacc atctacctga ctccagatgg taagcacgct atctctggtt acatgtacaa
    59941 cgagaaaggt gaaaacctga gtaacacact tatcgaaaaa gaaatttacg caccagccgg
    60001 acgcgaaatg tggcaacgga tggaacaatc ccactggctc ctcgacggta aaaaagatgc
    60061 gccggtcatt gtctacgtct tcgccgatcc gttctgccca tattgtaaac agttctggca
    60121 gcaggcgcgc ccgtgggtag attctggcaa agtgcaatta agaacattgt tggttggggt
    60181 tatcaagcca gaaagcccgg cgacagcagc ggcaattctt gcctccaaag atcccgcaaa
    60241 aacctggcaa caatatgaag cctctggtgg caagcttaag ctaaacgtgc ctgcaaacgt
    60301 aagtacagag caaatgaaag tgttaagtga caatgagaaa ctgatggacg atctgggggc
    60361 aaatgtcacg ccggctatct attacatgag taaggaaaat acgctacaac aggccgtggg
    60421 gttgcccgat cagaaaacgc ttaatatcat tatggggaat aaataaaagg taattcatgg
    60481 atggttgaac tatatccctg cttttcaacc atcctaaaaa agcatgaatt gctcgctctg
    60541 ccctaagtgg ctgtgctatt t
//
LOCUS       DAPOAV010000018        59128 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.018, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000018 DAPOAV010000000
VERSION     DAPOAV010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 59128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59128
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.018"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            118..2652
                     /gene="mrcB"
                     /locus_tag="RN951_001354"
     CDS             118..2652
                     /gene="mrcB"
                     /locus_tag="RN951_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glycosyl
                     transferase/transpeptidase"
                     /protein_id="HDX2526375.1"
                     /translation="MAGNDREPIGRKGKPTRPVKQKVSRRRYEDDDDYDDYDDYEDEE
                     PMPRKGKGKGKGRKPRGKRGWLWLLLKLAIVFAVLIAIYGVYLDQKIRSRIDGKVWQL
                     PAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFD
                     FPDSKEGQVRARLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISSPNGEQRLFVPR
                     SGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGASTLTQQLVKNL
                     FLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYY
                     FGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQQIIDQELYD
                     MLSARPLGVQPRGGVISPQPAFMQLVRQELQAKLGDKVKDLSGVKIFTTFDSVAQDAA
                     EKAAVEGIPALKKQRKLSDLETAIVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSI
                     GSLAKPATYLTALSQPKIYRLNTWIADAPIALRQPNGQVWSPQNDDRRYSESGRVMLV
                     DALTRSMNVPTVNLGMALGLPAVTETWIKLGVPKDQLHPVPAMLLGALNLTPIEVAQA
                     FQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLWTMQQVVQRGT
                     GRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTITWVGRDNNQPTKLYGASGAM
                     SIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGMRILPVWTSDPQSLCQQSE
                     MQQQPSGNPFDQSSQPQQQPQQQPAQQEQKDSDGVAGWIKDMFGSN"
     gene            2872..5115
                     /gene="fhuA"
                     /locus_tag="RN951_001355"
     CDS             2872..5115
                     /gene="fhuA"
                     /locus_tag="RN951_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrichrome porin FhuA"
                     /protein_id="HDX2526376.1"
                     /translation="MARSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITV
                     TAAPAPQESAWGPAATIAARQSATGTKTDTPIQKVPQSISVVTAEEMALHQPKSVKEA
                     LSYTPGVSVGTRGASNTYDHLIIRGFAAEGQSQNNYLNGLKLQGNFYNDAVIDPYMLE
                     RAEIMRGPVSVLYGKSSPGGLLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDSLD
                     DDGVYSYRLTGLARSANAQQKGSEEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGY
                     YGWLPKEGTVEPLPNGKRLPTDFNEGAKNNTYSRNEKMVGYSFDHEFNDTFTVRQNLR
                     FAENKTSQNSVYGYGVCSDPANAYSKQCAALAPADKGHYLARKYVVDDEKLQNFSVDT
                     QLQSKFATGDIDHTLLTGVDFMRMRNDINAWFGYDDSVPLLNLYNPVNTDFDFNAKDP
                     ANSGPYRILNKQKQTGVYVQDQAQWDKVLVTLGGRYDWADQESLNRVAGTTDKRDDKQ
                     FTWRGGVNYLFDNGVTPYFSYSESFEPSSQVGKDGNIFAPSKGKQYEVGVKYVPEDRP
                     IVVTGAVYNLTKTNNLMADPEGSFFSVEGGEIRARGVEIEAKAALSASVNVVGSYTYT
                     DAEYTTDTTYKGNTPAQVPKHMASLWADYTFFDGPLSGLTLGTGGRYTGSSYGDPANS
                     FKVGSYTVVDALVRYDLARVGMAGSNVALHVNNLFDREYVASCFNTYGCFWGAERQVV
                     ATATFRF"
     gene            5166..5963
                     /gene="fhuC"
                     /locus_tag="RN951_001356"
     CDS             5166..5963
                     /gene="fhuC"
                     /locus_tag="RN951_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe3+-hydroxamate ABC transporter ATP-binding
                     protein FhuC"
                     /protein_id="HDX2526377.1"
                     /translation="MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIG
                     HNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAEGMTV
                     RELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAM
                     LVAQDSRCLLLDEPTSALDIAHQVDVLSLVHRLSQERGLTVIAVLHDINMAARYCDYL
                     VALRGGEMIAQGTPAEIMRGETLEMIYGIPMGILPHPAGAAPVSFVY"
     gene            5963..6853
                     /gene="fhuD"
                     /locus_tag="RN951_001357"
     CDS             5963..6853
                     /gene="fhuD"
                     /locus_tag="RN951_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter
                     substrate-binding protein FhuD"
                     /protein_id="HDX2526378.1"
                     /translation="MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWL
                     PVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVW
                     SAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYED
                     FIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWG
                     STAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYG
                     ATLSAMHFVRVLDNAIGGKA"
     gene            6850..8832
                     /gene="fhuB"
                     /locus_tag="RN951_001358"
     CDS             6850..8832
                     /gene="fhuB"
                     /locus_tag="RN951_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter permease
                     FhuB"
                     /protein_id="HDX2526379.1"
                     /translation="MSKRIALFPALLLALLVIVATALTWMNFSQALPRSQWAQAAWSP
                     DIDVIEQMIFHYSLLPRLVISLLVGAGLGLVGVLFQQVLRNPLAEPTTLGVATGAQLG
                     ITVTTLWAIPGAMASQFAALAGACVVGLIVFGVAWGKRLSPVTLILAGLVVSLYCGAI
                     NQLLVIFHHDQLQSMFLWSTGTLTQTDWGGVERLWPQLLGGVMLTLLLLRPLTLMGLD
                     DGVARNLGLALSLARLAALSLAIVISALLVNAVGIIGFIGLFAPLLAKMLGARRLLPR
                     LMLASLIGALILWLSDQIILWLTRVWMEVSTGSVTALIGAPLLLWLLPRLRSISAPDM
                     KVNDRVAAERQHVLAFALAGGVLLLMAVVVALSFGRDAHGWTWASGALLEDLMPWRWP
                     RIMAALFAGVMLAVAGCIIQRLTGNPMASPEVLGISSGAAFGVVLMLFLVPGNAFGWL
                     LPAGSLGAAVTLLIIMIAAGRSGFSPHRMLLAGMALSTAFTMLLMMLQASGDPRMAQV
                     LTWISGSTYNATDAQVWRTGIVMVILLAITPLCRRWLTILPLGGDTARAVGMALTPTR
                     IALLLLAACLTATATMTIGPLSFVGLMAPHIARMMGFRRTMPHIVISALVGGLLLVFA
                     DWCGRMVLFPFQIPAGLLSTFIGAPYFIYLLRKQSR"
     gene            complement(8990..10270)
                     /gene="hemL"
                     /locus_tag="RN951_001359"
     CDS             complement(8990..10270)
                     /gene="hemL"
                     /locus_tag="RN951_001359"
                     /EC_number="5.4.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="HDX2526380.1"
                     /translation="MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYL
                     YDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTEL
                     VPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTL
                     GQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPE
                     FLPGLRALCDEFGTLLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAF
                     GGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGVHETLDELTTRLAEG
                     LLEAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVY
                     LAPSAFEAGFMSVAHSMEDINNTIDAARRVFAKL"
     gene            10495..11916
                     /gene="clcA"
                     /locus_tag="RN951_001360"
     CDS             10495..11916
                     /gene="clcA"
                     /locus_tag="RN951_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H(+)/Cl(-) exchange transporter ClcA"
                     /protein_id="HDX2526381.1"
                     /translation="MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGT
                     LVGLAAVAFDKGVAWLQNQRMGALVHTADNYSLLLTVAFLCSAVLAMFGYFLVRKYAP
                     EAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGR
                     MVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAV
                     FIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGM
                     QDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLV
                     FIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIA
                     GMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILA
                     RTLAKQEAEQLARSKAASASENT"
     gene            11940..12005
                     /locus_tag="RN951_001361"
     CDS             11940..12005
                     /locus_tag="RN951_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526382.1"
                     /translation="MAIIIGLEFAQLPMSFGAKYE"
     gene            11998..12342
                     /gene="erpA"
                     /locus_tag="RN951_001362"
     CDS             11998..12342
                     /gene="erpA"
                     /locus_tag="RN951_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster insertion protein ErpA"
                     /protein_id="HDX2526383.1"
                     /translation="MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSG
                     FQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNA
                     KSTCGCGSSFSI"
     gene            complement(12389..13012)
                     /locus_tag="RN951_001363"
     CDS             complement(12389..13012)
                     /locus_tag="RN951_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRIC cation channel family protein"
                     /protein_id="HDX2526384.1"
                     /translation="MLVYWLDIVGTAVFAISGVLLAGKLRMDPFGVLVLGVVTAVGGG
                     TIRDMALDHGPVFWVKDPTDLVVAMVTSMLTIVLVRQPRRLPKWMLPVLDAVGLAVFV
                     GIGVNKAFNAEAGPLIAVCMGVITGVGGGIIRDVLAREIPMILRTEIYATACIIGGIV
                     HATAYYTFSVPLETASMMGMVVTLLIRLAAIRWHLKLPTFALDENGR"
     gene            complement(13050..13850)
                     /gene="btuF"
                     /locus_tag="RN951_001364"
     CDS             complement(13050..13850)
                     /gene="btuF"
                     /locus_tag="RN951_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter substrate-binding
                     protein BtuF"
                     /protein_id="HDX2526385.1"
                     /translation="MAKSLFRALVALSFLAPLWLNAAPRVITLSPANTELAFAAGITP
                     VGVSSYSDYPPQAQKIEQVSTWQGMNLERIVALKPDLVIAWRGGNAERQVDQLASLGI
                     KVMWVDATSIEQIANALRQLAPWSPQPDKAEQAAQSLLDQYAQLKAQYADKPKKRVFL
                     QFGINPPFTSGKESIQNQVLEVCGGENIFKDSRVPWPQVSREQVLARSPQAIVITGGP
                     DQIPKIKQYWGEQLKIPVIPLTSDWFERASPRIILAAQQLCNALSQVD"
     gene            complement(13843..14541)
                     /gene="mtnN"
                     /locus_tag="RN951_001365"
     CDS             complement(13843..14541)
                     /gene="mtnN"
                     /locus_tag="RN951_001365"
                     /EC_number="3.2.2.16"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HDX2526386.1"
                     /translation="MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVA
                     LLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADV
                     TAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAK
                     IRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQS
                     SLMVESLVQKLAHG"
     gene            14625..16142
                     /gene="dgt"
                     /locus_tag="RN951_001366"
     CDS             14625..16142
                     /gene="dgt"
                     /locus_tag="RN951_001366"
                     /EC_number="3.1.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dGTPase"
                     /protein_id="HDX2526387.1"
                     /translation="MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPA
                     IRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDEL
                     TGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAAL
                     RLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWW
                     RGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVAD
                     LEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFM
                     YLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFS
                     HPDVEQLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTR
                     HRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ"
     gene            16272..17696
                     /gene="degP"
                     /locus_tag="RN951_001367"
     CDS             16272..17696
                     /gene="degP"
                     /locus_tag="RN951_001367"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegP"
                     /protein_id="HDX2526388.1"
                     /translation="MKKTTLALSALALSLGLALSPLSATAAETSSATTAQQMPSLAPM
                     LEKVMPSVVSINVEGSTTVNTPRMPRNFQQFFGDDSPFCQEGSPFQSSPFCQGGQGGN
                     GGGQQQKFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRS
                     DIALIQIQNPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNA
                     ENYENFIQTDAAINRGNSGGALVNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNL
                     TSQMVEYGQVKRGELGIMGTELNSELAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAGD
                     VITSLNGKPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQSSQNQVDSSS
                     IFNGIEGAEMSNKGKDQGVVVNNVKTGTPAAQIGLKKGDVIIGANQQAVKNIAELRKV
                     LDSKPSVLALNIQRGDSTIYLLMQ"
     gene            17851..19008
                     /gene="cdaR"
                     /locus_tag="RN951_001368"
     CDS             17851..19008
                     /gene="cdaR"
                     /locus_tag="RN951_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414704.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CdaR"
                     /protein_id="HDX2526389.1"
                     /translation="MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERI
                     GELHEGALLVLSQGRVVDIDDAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPENLR
                     KYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDL
                     NQPRVVAIVEVDSGQLGVDSAMAELQQLQNALTTPERNNLVAIVSLTEMVVLKPALNS
                     FGRWDAEDHRKRVEQLITRMKEYGQLRFRVSLGNYFTGPGSIARSYRTAKTTMVVGKQ
                     RMPESRCYFYQDLMLPVLLDSLRGDWQANELARPLARLKTMDNNGLLRRTLAAWFRHN
                     VQPLATSKALFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEER"
     gene            complement(19097..19483)
                     /locus_tag="RN951_001369"
     CDS             complement(19097..19483)
                     /locus_tag="RN951_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3461 family protein"
                     /protein_id="HDX2526390.1"
                     /translation="MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAK
                     SVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILD
                     DLRHLESVVTNKISEIEADLEKLTRK"
     gene            complement(19645..20457)
                     /gene="yaeI"
                     /locus_tag="RN951_001370"
     CDS             complement(19645..20457)
                     /gene="yaeI"
                     /locus_tag="RN951_001370"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414706.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase YaeI"
                     /protein_id="HDX2526391.1"
                     /translation="MISRRRFLQATAATIATSSGFGYMHYCEPGWFELIRHRLAFFKD
                     NAAPFKILFLADLHYSRFVPLSLISDAIALGIEQKPDLILLGGDYVLFDMSLNFSAFS
                     DVLSPLAECAPTFACFGNHDRPVGTEKNHLIGETLKSAGITVLFNQATVIATPNRQFE
                     LVGTGDLWAGQCKPPPASEANLPRLVLAHNPDSKEVMRDEPWDLMLCGHTHGGQLRVP
                     LVGEPFAPVEDKRYVAGLNAFGERHIYTTRGVGSLYGLRLNCRPEVTMLELV"
     gene            complement(20511..21335)
                     /gene="dapD"
                     /locus_tag="RN951_001371"
     CDS             complement(20511..21335)
                     /gene="dapD"
                     /locus_tag="RN951_001371"
                     /EC_number="2.3.1.117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase"
                     /protein_id="HDX2526392.1"
                     /translation="MQQLQNIIETAFERRAEITPANADTVTREAVNQVIALLDSGALR
                     VAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRYFDKVPMKFADYDEARFQKEG
                     FRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
                     GVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRE
                     TGEIHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID"
     gene            complement(21366..24038)
                     /gene="glnD"
                     /locus_tag="RN951_001372"
     CDS             complement(21366..24038)
                     /gene="glnD"
                     /locus_tag="RN951_001372"
                     /EC_number="2.7.7.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     uridylyltransferase/uridylyl-removing protein GlnD"
                     /protein_id="HDX2526393.1"
                     /translation="MNTLPEQYANTALPTLPGQPQNPCVWPRDELTVGGIKAHIDTFQ
                     RWLGDAFDNGISAEQLIEARTEFIDQLLQRLWIEAGFSQIADLALVAVGGYGRGELHP
                     LSDVDLLILSRKKLPDDQAQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVAT
                     NLIESRLLIGDVALFLELQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPD
                     IKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTSAERAELNECLHILWRIRFAL
                     HLVVSRYDNRLLFDRQLSVAQRLNYSGEGNEPVERMMKDYFRVTRRVSELNQMLLQLF
                     DEAILALPADEKPRPIDDEFQLRGTLIDLRDETLFMRQPEAILRMFYTMVHNSAITGI
                     YSTTLRQLRHARRHLQQPLCNIPEARKLFLSILRHPGAVRRGLLPMHRHSVLGAYMPQ
                     WSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFASEETRQRHPLCVDVWPRLPSTELIF
                     IAALFHDIAKGRGGDHSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMSVTAQRR
                     DIQDPEVIKQFAEEVQTENRLRYLVCLTVADICATNETLWNSWKQSLLRELYFATEKQ
                     LRRGMQNTPDMRERVRHHQLQALALLRMDNIDEEALHQIWSRCRANYFVRHSPNQLAW
                     HARHLLQHDLSKPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQI
                     FTTRDGMAMDTFIVLEPDGNPLSADRHEVIRFGLEQVLTQSSWQPPQPRRQPAKLRHF
                     TVETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGISLHGARITTIGERVED
                     LFIIATADRRALNNELQQEVHQRLTEALNPNDKG"
     gene            complement(24100..24894)
                     /gene="map"
                     /locus_tag="RN951_001373"
     CDS             complement(24100..24894)
                     /gene="map"
                     /locus_tag="RN951_001373"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HDX2526394.1"
                     /translation="MAISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRI
                     CNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIK
                     DGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAE
                     GFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMK
                     DGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE"
     gene            25262..25987
                     /gene="rpsB"
                     /locus_tag="RN951_001374"
     CDS             25262..25987
                     /gene="rpsB"
                     /locus_tag="RN951_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HDX2526395.1"
                     /translation="MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLE
                     KTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLT
                     NWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDA
                     LFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVA
                     ATVREGRSQDLASQAEESFVEAE"
     gene            26245..27096
                     /gene="tsf"
                     /locus_tag="RN951_001375"
     CDS             26245..27096
                     /gene="tsf"
                     /locus_tag="RN951_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HDX2526396.1"
                     /translation="MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKS
                     GAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVA
                     GKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKG
                     ADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEG
                     RMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEV
                     AAMSKQS"
     gene            27243..27968
                     /gene="pyrH"
                     /locus_tag="RN951_001376"
     CDS             27243..27968
                     /gene="pyrH"
                     /locus_tag="RN951_001376"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HDX2526397.1"
                     /translation="MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKEL
                     VELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNA
                     RLMSAIPLNGVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADV
                     VLKATKVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVF
                     NMNKPGALRRVVMGEKEGTLITE"
     gene            28260..28817
                     /gene="frr"
                     /locus_tag="RN951_001377"
     CDS             28260..28817
                     /gene="frr"
                     /locus_tag="RN951_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HDX2526398.1"
                     /translation="MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEY
                     YGTPTPLRQLASVTVEDSRTLKINVFDRSMSPAVEKAIMASDLGLNPNSAGSDIRVPL
                     PPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDV
                     QKLTDAAIKKIEAALADKEAELMQF"
     gene            28909..30105
                     /gene="ispC"
                     /locus_tag="RN951_001378"
     CDS             28909..30105
                     /gene="ispC"
                     /locus_tag="RN951_001378"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HDX2526399.1"
                     /translation="MKQLTILGSTGSIGCSTLDVVRHNPEHFRVVALVAGKNVTRMVE
                     QCLEFSPRYAVMDDEASAKLLKTMLQQQGSRTEVLSGQQAACDMAALEDVDQVMAAIV
                     GAAGLLPTLAAIRAGKTILLANKESLVTCGRLFMDAVKQSKAQLLPVDSEHNAIFQSL
                     PQPIQHNLGYADLEQNGVVSILLTGSGGPFRETPLRDLATMTPDQACRHPNWSMGRKI
                     SVDSATMMNKGLEYIEARWLFNASASQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDM
                     RTPIAHTMAWPNRVNSGVKPLDFCKLSALTFAAPDYDRYPCLKLAMEAFEQGQAATTA
                     LNAANEITVAAFLAQQIRFTDIAALNLSVLEKMDMREPQCVDDVLSVDANAREVARKE
                     VMRLAS"
     gene            30294..31052
                     /gene="ispU"
                     /locus_tag="RN951_001379"
                     /gene_synonym="uppS"
     CDS             30294..31052
                     /gene="ispU"
                     /locus_tag="RN951_001379"
                     /gene_synonym="uppS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308203.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl-diphosphate-specific
                     ditrans,polycis-undecaprenyl-diphosphate synthase"
                     /protein_id="HDX2526400.1"
                     /translation="MLSATQPLSEKLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKA
                     GAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRH
                     NVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEK
                     VQQGNLQPDQIDEEMLNQHVCMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDV
                     LWPDFDEQDFEGALNAFANRERRFGGTEPGDETA"
     gene            31065..31922
                     /gene="cdsA"
                     /locus_tag="RN951_001380"
     CDS             31065..31922
                     /gene="cdsA"
                     /locus_tag="RN951_001380"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414717.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDX2526401.1"
                     /translation="MLKYRLISAFVLIPVVIAALFLLPPVGFAIVTLVVCMLAAWEWG
                     QLSGFTTRSQRVWLAVLCGLLLALMLFLLPEYHRNIHQPLVEISLWASLGWWIVALLL
                     VLFYPGSAAIWRNSKTLRLIFGVLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMIL
                     VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLATAAVISWGYGMWANLDVAPV
                     TLLICSIVAALASVLGDLTESMFKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFAC
                     LLLLVFRTL"
     gene            31934..33286
                     /gene="rseP"
                     /locus_tag="RN951_001381"
     CDS             31934..33286
                     /gene="rseP"
                     /locus_tag="RN951_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma E protease regulator RseP"
                     /protein_id="HDX2526402.1"
                     /translation="MLSFLWDLASFIVALGVLITVHEFGHFWVARRCGVRVERFSIGF
                     GKALWRRTDKLGTEYVIALIPLGGYVKMLDERAEPVVPELRHHAFNNKSVGQRAAIIA
                     AGPVANFIFAIFAYWLVFIIGVPGVRPVVGEIAANSIAAEAQIAPGTELKAVDGIETP
                     DWDAVRLQLVDKIGDESTTITVAPFGSDQRRDVKLDLRHWAFEPDKEDPVSSLGIRPR
                     GPQIEPVLENVQPNSAASKAGLQAGDRIVKVDGQPLTQWVTFVMLVRDNPGKSLALEI
                     ERQGSPLSLTLIPESKPGNGKAIGFVGIEPKVIPLPDEYKVVRQYGPFNAIVEATDKT
                     WQLMKLTVSMLGKLITGDVKLNNLSGPISIAKGAGMTAELGVVYYLPFLALISVNLGI
                     INLFPLPVLDGGHLLFLAIEKIKGGPVSERVQDFCYRIGSILLVLLMGLALFNDFSRL
                     "
     gene            33316..35748
                     /gene="bamA"
                     /locus_tag="RN951_001382"
     CDS             33316..35748
                     /gene="bamA"
                     /locus_tag="RN951_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamA"
                     /protein_id="HDX2526403.1"
                     /translation="MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALL
                     SMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGDTLLVQVKERPTIASITFSGN
                     KSVKDDMLKQNLEASGVRVGESLDRTTIADIEKGLEDFYYSVGKYSASVKAVVTPLPR
                     NRVDLKLVFQEGVSAEIQQINIVGNHAFTTDELISHFQLRDEVPWWNVVGDRKYQKQK
                     LAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYVTVNITEGDQYKLSGVEVSGN
                     LAGHSAEIEQLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSMPEINDADKT
                     VKLRVNVDAGNRFYVRKIRFEGNDTSKDAVLRREMRQMEGAWLGSDLVDQGKERLNRL
                     GFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWL
                     GTGYAVGINGTKNDYQTYAELSVTNPYFTVDGVSLGGRLFYNDFQADDADLSDYTNKS
                     YGTDVTLGFPINEYNSLRAGLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFK
                     TDDFTFNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDDD
                     HKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYFPHQASNY
                     DPDYDYECATQDGAKDLCKSDDAVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWD
                     MGTVWDTNWDSSQYSGYPDYSDPSNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDK
                     AEQFQFNIGKTW"
     gene            35870..36355
                     /gene="skp"
                     /locus_tag="RN951_001383"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
     CDS             35870..36355
                     /gene="skp"
                     /locus_tag="RN951_001383"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone Skp"
                     /protein_id="HDX2526404.1"
                     /translation="MKKWLLAAGLGLALATSAQAADKIAIVNMGSLFQQVAQKTGVSN
                     TLENEFKGRASELQRMETDLQAKMKKLQSMKAGSDRTKLEKDVMAQRQTFAQKAQAFE
                     QDRARRSNEERGKLVTRIQTAVKSVANSQDIDLVVDANAVAYNSSDVKDITADVLKQV
                     K"
     gene            36359..37384
                     /gene="lpxD"
                     /locus_tag="RN951_001384"
     CDS             36359..37384
                     /gene="lpxD"
                     /locus_tag="RN951_001384"
                     /EC_number="2.3.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-(3-hydroxymyristoyl)glucosamine
                     N-acyltransferase"
                     /protein_id="HDX2526405.1"
                     /translation="MPSIRLADLAQQLDAELHGDGDIVITGVASMQSAQTGHITFMVN
                     PKYREHLGLCQASAVVMTQDDLPFAKSAALVVKNPYLTYARMAQILDTTPQPAQNIAP
                     SAVIDATAKLGNNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAGSRLWANVTI
                     YHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQIGRVIIGDRVEIGACTTIDRG
                     ALDDTIIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKIGRYCMIGGASVINGH
                     MEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKTAALVMNIDDMSKRLKSLE
                     RKVNQQD"
     gene            37489..37944
                     /gene="fabZ"
                     /locus_tag="RN951_001385"
     CDS             37489..37944
                     /gene="fabZ"
                     /locus_tag="RN951_001385"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDX2526406.1"
                     /translation="MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNV
                     SVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFK
                     RPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA"
     gene            37948..38736
                     /gene="lpxA"
                     /locus_tag="RN951_001386"
     CDS             37948..38736
                     /gene="lpxA"
                     /locus_tag="RN951_001386"
                     /EC_number="2.3.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP--UDP-N-acetylglucosamine
                     O-acyltransferase"
                     /protein_id="HDX2526407.1"
                     /translation="MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVL
                     KSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGT
                     VQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVH
                     QFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNA
                     YKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR"
     gene            38736..39884
                     /gene="lpxB"
                     /locus_tag="RN951_001387"
     CDS             38736..39884
                     /gene="lpxB"
                     /locus_tag="RN951_001387"
                     /EC_number="2.4.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-A-disaccharide synthase"
                     /protein_id="HDX2526408.1"
                     /translation="MTEQRPLTIALVAGETSGDILGAGLIRALKEHVPNARFVGVAGP
                     RMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDF
                     NITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVP
                     CRFIGHTMADAMPLDPDKNAARDVLGIPHDAHCLALLPGSRGAEVEMLSADFLKTAQL
                     LRQTYPDLEIVVPLVNAKRREQFERIKAEVAPDLSVHLLDGMGREAMVASDAALLASG
                     TAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEP
                     QKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ"
     gene            39881..40477
                     /gene="rnhB"
                     /locus_tag="RN951_001388"
     CDS             39881..40477
                     /gene="rnhB"
                     /locus_tag="RN951_001388"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HDX2526409.1"
                     /translation="MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLN
                     DSKKLSEKRRLALYEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAP
                     EYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAVLDIVFPQYGFA
                     QHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS"
     gene            40514..43996
                     /gene="dnaE"
                     /locus_tag="RN951_001389"
     CDS             40514..43996
                     /gene="dnaE"
                     /locus_tag="RN951_001389"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HDX2526410.1"
                     /translation="MSEPRFVHLRVHSDYSMIDGLAKTAPLVKKAAALGMPALAITDF
                     TNLCGLVKFYGAGHGAGIKPIVGADFNVQCDLLGDELTHLTVLAANNTGYQNLTLLIS
                     KAYQRGYGAAGPIIDRDWLIELNEGLILLSGGRMGDVGRSLLRGNSALVDECVAFYEE
                     HFPDRYFLELIRTGRPDEESYLHAAVELAEARGLPVVATNDVRFIDSSDFDAHEIRVA
                     IHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFADIPEALANTVEIAKRCNVTVRLGEY
                     FLPQFPTGDMSTEDYLVKRAKEGLEERLAFLFPDEEEHLKRRPEYDERLETELQVINQ
                     MGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFL
                     NPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLG
                     HPYGFVDRISKLIPPDPGMTLAKAFEAEPQLPEIYEADEEVKALIDMARKLEGVTRNA
                     GKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIIN
                     WALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVFQLESRGMKDLIKRLQ
                     PDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREEISYPDVQWQHESLKPVLEPTYG
                     IILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFAEGAEKNGINAEL
                     AMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTADMDNTEKVV
                     GLVDECWRMGLKILPPDINSGLYHFHVNDDGEIVYGIGAIKGVGEGPIEAIIEARNKG
                     GYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLGDALKAADQHAK
                     AEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTGHPINQYLKE
                     IERYVGGVRLKDMHPTERGKVITAAGLVVAARVMVTKRGNRIGICTLDDRSGRLEVML
                     FTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARGLAISL
                     TDRQIDDQLLNRLRQSLEPHRSGTIPVHLYYQRADARARLRFGATWRVSPSDRLLNDL
                     RGLIGSEQVELEFD"
     gene            44009..44968
                     /gene="accA"
                     /locus_tag="RN951_001390"
     CDS             44009..44968
                     /gene="accA"
                     /locus_tag="RN951_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HDX2526411.1"
                     /translation="MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLR
                     EKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIV
                     GGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITF
                     IDTPGAYPGVGAEERGQSEAIARNLREMSRLGVPVVCTVIGEGGSGGALAIGVGDKVN
                     MLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAH
                     RNPEAMAASLKAQLLADLADLDVLSTEDLKNRRYQRLMSYGYA"
     gene            45067..47208
                     /gene="ldcC"
                     /locus_tag="RN951_001391"
     CDS             45067..47208
                     /gene="ldcC"
                     /locus_tag="RN951_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase LdcC"
                     /protein_id="HDX2526412.1"
                     /translation="MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLK
                     FIEHNPRICGVIFDWDEYSLDLCSDINQLNEYLPLYAFINTHSTMDVSVQDMRMALWF
                     FEYALGQAEDIAIRMRQYTDEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQK
                     SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYIVTN
                     GTSTSNKIVGMYAAPSGSTLLIDRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIP
                     RREFTRDSIEEKVAATTQAQWPVHAVITNSTYDGLLYNTDWIKQTLDVPSIHFDSAWV
                     PYTHFHPIYQGKSGMSGERVAGKVIFETQSTHKMLAALSQASLIHIKGEYDEEAFNEA
                     FMMHTTTSPSYPIVASVETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDGWF
                     FDIWQPPQVDEAECWPVAPGEQWHGFNDADADHMFLDPVKVTILTPGMDEQGNMSEEG
                     IPAALVAKFLDERGIVVEKTGPYNLLFLFSIGIDKTKAMGLLRGLTEFKRSYDLNLRI
                     KNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKHDLPGLMLRAFDTLPEMIMTPHQAW
                     QRQIKGEVETIALEQLVGRVSANMILPYPPGVPLLMPGEMLTKESRTVLDFLLMLCSV
                     GQHYPGFETDIHGAKQDEDGVYRVRVLKMAG"
     gene            47265..47654
                     /locus_tag="RN951_001392"
     CDS             47265..47654
                     /locus_tag="RN951_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414729.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDX2526413.1"
                     /translation="MLGLKQVHHIAIIATDYAVSKAFYCDILGFTLQSEVYREARDSW
                     KGDLALNGQYVIELFSFPFPPERPSRPEACGLRHLAFSVDDIDAAVAHLESHNVKCET
                     IRVDPYTQKRFTFFNDPDGLPLELYEQ"
     gene            47719..49017
                     /gene="tilS"
                     /locus_tag="RN951_001393"
     CDS             47719..49017
                     /gene="tilS"
                     /locus_tag="RN951_001393"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HDX2526414.1"
                     /translation="MTLTLNRQLLTSRQILVAFSGGLDSTVLLHQLVQWRTENPGVAL
                     RAIHVHHGLSANADAWVTHCENVCQQWQVPLVVERVQLAQEGLGIEAQARQARYQAFA
                     RTLLPGEVLVTAQHLDDQCETFLLALKRGSGPAGLSAMAEVSEFAGTRLIRPLLARTR
                     GELVQWARQYDLRWIEDESNQDDSYDRNFLRLRVVPLLQQRWPHFAEATARSAALCAE
                     QESLLDELLADDLAHCQSPQGTLQIVPMLAMSDARRAAIIRRWLAGQNAPMPSRDALV
                     RIWQEVALAREDASPCLRLGAFEIRRYQSQLWWIKSVTGQSENIVPWQTWLQPLELPA
                     GLGSVQLNAGGDIRPPRADEAVSVRFKAPGLLHIVGRNGGRKLKKIWQELGVPPWLRD
                     TTPLLFYGETLIAAAGVFVTQEGVAEGENGVSFVWQKTLS"
     gene            complement(49066..49326)
                     /gene="rof"
                     /locus_tag="RN951_001394"
     CDS             complement(49066..49326)
                     /gene="rof"
                     /locus_tag="RN951_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho-binding antiterminator"
                     /protein_id="HDX2526415.1"
                     /translation="MSMNDTYQPINCDDYDNLELACQHHLMLTLELKDGEKLQAKASD
                     LVSRKNVEYLVVEAAGETRELRLDKITSFSHPEIGTVVVSES"
     gene            complement(49313..49513)
                     /locus_tag="RN951_001395"
     CDS             complement(49313..49513)
                     /locus_tag="RN951_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeP family protein"
                     /protein_id="HDX2526416.1"
                     /translation="MEKYCELIRKRYAEIASGDLGYVPDALGCVLKVLNEMAADDALS
                     EAVREKAAYAAANLLVSDYVNE"
     gene            49679..50224
                     /locus_tag="RN951_001396"
     CDS             49679..50224
                     /locus_tag="RN951_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeQ family protein"
                     /protein_id="HDX2526417.1"
                     /translation="MALKATIYKATVNVADLDRNQFLDASLTLARHPSETQERMMLRL
                     LAWLKYADERLQFTRGLCADDEPEAWLRNDHLGIDLWIELGLPDERRIKKACTQAAEV
                     ALFTYNSRAAQIWWQQNQSKCVQFANLSVWYLDDEQLAKVSAFADRTMTLQATIQDGV
                     IWLSDDKNNLEVNLTAWQQPS"
     gene            50221..50643
                     /gene="arfB"
                     /locus_tag="RN951_001397"
     CDS             50221..50643
                     /gene="arfB"
                     /locus_tag="RN951_001397"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDX2526418.1"
                     /translation="MIVISRHVAIPDGELEITAIRAQGAGGQHVNKTSTAIHLRFDIR
                     ASRLPEYYKERLLAASHHLISSDGVIVIKAQEYRSQELNREAALARLVAMIKELTTEK
                     KARRPTRPTRASKERRLASKAQKSSVKAMRGKVRSGRE"
     gene            50657..51367
                     /gene="nlpE"
                     /locus_tag="RN951_001398"
                     /gene_synonym="cutF"
     CDS             50657..51367
                     /gene="nlpE"
                     /locus_tag="RN951_001398"
                     /gene_synonym="cutF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414734.1"
                     /note="NlpE, an outer membrane lipoprotein, interacts
                     directly with CpxA, the sensor histidine kinase of the Cpx
                     system for response to envelope stress; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response activation lipoprotein
                     NlpE"
                     /protein_id="HDX2526419.1"
                     /translation="MVKKAIVTAMAVISLFTLMGCNNRAEVDTLSPAQAAELKPMPQS
                     WRGVLPCADCEGIETSLFLEKDGTWVMNERYLGAREEPSSFASYGTWARTADKLVLTD
                     SKGEKSYYRAKGDALEMLDREGNPIESQFNYTLEAAQSSLPMTPMTLRGMYFYMADAA
                     TFTDCATGKRFMVANNAELERSYLAARGHSEKPVLLSVEGHFTLEGNPDTGAPTKVLA
                     PDTAGKFYPNQDCSSLGQ"
     gene            complement(51567..52391)
                     /locus_tag="RN951_001399"
     CDS             complement(51567..52391)
                     /locus_tag="RN951_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414735.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeF family permuted papain-like enzyme"
                     /protein_id="HDX2526420.1"
                     /translation="MDKPKAYCRLFLPSFLLLSACTVDISQPDPSATAVDAEAKTWAV
                     KFQHQSSFTEQSIKEITAPDLKPGDLLFSSSLGVTSFGIRVFSTSSVSHVAIFLGDNN
                     VAEATGAGVQIVSLKKAMKHSDKLFVLRVPDLTPQQATDITAFANKIKDSGYNYRGIV
                     EFIPFMVTRQMCSLNPFSEDFRQQCVSGLAKAQLSSVGEGDKKSWFCSEFVTDAFAKA
                     GHPLTLAQSGWISPADLMHMRIGDVSAFKPETQLQYVGHLKPGIYIKAGRFVGLTR"
     gene            complement(52445..54163)
                     /gene="proS"
                     /locus_tag="RN951_001400"
     CDS             complement(52445..54163)
                     /gene="proS"
                     /locus_tag="RN951_001400"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDX2526421.1"
                     /translation="MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLP
                     TGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGER
                     PFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDA
                     YSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGE
                     DDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEK
                     TVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAG
                     PGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEVADIRNVVA
                     GDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTR
                     VVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVL
                     LDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVEYL
                     VKQIKG"
     gene            complement(54275..54982)
                     /gene="tsaA"
                     /locus_tag="RN951_001401"
     CDS             complement(54275..54982)
                     /gene="tsaA"
                     /locus_tag="RN951_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase
                     TrmO"
                     /protein_id="HDX2526422.1"
                     /translation="MSSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQ
                     ADAVRGLEAFSHLWILFVFHQTMEGGWRPTVRPPRLGGNARMGVFATRSTFRPNPIGM
                     SLVELKEVVCHKDSVILKLGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAE
                     MAVSFTAEVEKQLLTLEKRYPQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNV
                     RWRVTDAGFEVFALEPR"
     gene            complement(54979..55383)
                     /gene="rcsF"
                     /locus_tag="RN951_001402"
     CDS             complement(54979..55383)
                     /gene="rcsF"
                     /locus_tag="RN951_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rcs stress response system protein RcsF"
                     /protein_id="HDX2526423.1"
                     /translation="MRALPICLVALMLSGCSMLSRSPVEPVQSTAPQPKAEPAKPKAP
                     RATPVRIYTNAEELVGKPFRDLGEVSGDSCQASNQDSPPSIPTARKRMQINASKMKAN
                     AVLLHSCEVTSGTPGCYRQAVCIGSALNITAK"
     gene            complement(55501..56316)
                     /gene="metQ"
                     /locus_tag="RN951_001403"
     CDS             complement(55501..56316)
                     /gene="metQ"
                     /locus_tag="RN951_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter substrate-binding
                     lipoprotein MetQ"
                     /protein_id="HDX2526424.1"
                     /translation="MAFKFKTFAAVGALIGSLALVGCGQDEKDPNHIKVGVIVGAEQQ
                     VAEVAQKVAKDKYGLDVELVTFNDYVLPNEALSKGDIDANAFQHKPYLDQQLKDRGYK
                     LVAVGNTFVYPIAGYSKKIKSLDELQDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDG
                     VGLLPTVLDVVENPKNLKIVELEAPQLPRSLDDAQIALAVINTTYASQIGLTPAKDGI
                     FVEDKESPYVNLIVTREDNKDAENVKKFVQAYQSDEVYEAANKVFNGGAVKGW"
     gene            complement(56356..57009)
                     /gene="metI"
                     /locus_tag="RN951_001404"
     CDS             complement(56356..57009)
                     /gene="metI"
                     /locus_tag="RN951_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease MetI"
                     /protein_id="HDX2526425.1"
                     /translation="MSEPMMWLLVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPG
                     QIIANAKLYRTVSAIVNIFRSIPFIILLVWMIPFTRVIVGTSIGLQAAIVPLTVGAAP
                     FIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGY
                     SAMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVILVYLIQFAGDRIVRAVTRK"
     gene            complement(57002..58033)
                     /gene="metN"
                     /locus_tag="RN951_001405"
     CDS             complement(57002..58033)
                     /gene="metN"
                     /locus_tag="RN951_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein
                     MetN"
                     /protein_id="HDX2526426.1"
                     /translation="MIKLSNITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGK
                     STLIRCVNLLERPTEGSVLVDGQELTTLSESELTKARRQIGMIFQHFNLLSSRTVFGN
                     VALPLELDNTPKDEVKRRVTELLSLVGLGDKHDSYPSNLSGGQKQRVAIARALASNPK
                     VLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGE
                     LIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQ
                     SVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHH
                     VKVEVLGYV"
     gene            58221..58796
                     /gene="gmhB"
                     /locus_tag="RN951_001406"
     CDS             58221..58796
                     /gene="gmhB"
                     /locus_tag="RN951_001406"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HDX2526427.1"
                     /translation="MAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKK
                     MGFALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRDVDLDGIYYCPHHPQGSVEE
                     FRQVCDCRKPHPGMLLSARDYLHIDMAASYMVGDKLEDMQAAVAANVGTKVLVRTGKP
                     ITPEAENAADWVLNSLADLPQAIKKQQKPAQ"
BASE COUNT        14020 a        14675 c        16246 g        14187 t
ORIGIN      
        1 tctccctcaa gggagagggg accgatcgag cacaaatttt gagagatatc ttcttctgtc
       61 ttgtaacaga agaacagaaa atcgggcttt tgcgcctgaa tattgcggag aaaaagcatg
      121 gccgggaatg accgcgagcc aattggacgc aaagggaaac cgacgcgtcc ggtcaaacaa
      181 aaggtaagcc gtcgtcgtta cgaagatgac gatgattacg acgattatga tgactatgag
      241 gatgaagaac cgatgccgcg caaaggtaag ggcaaaggca aagggcgtaa gcctcgtggc
      301 aaacgcggct ggctatggct actgctaaaa ctggctatcg tttttgccgt gctgatcgcc
      361 atttacggcg tttatctcga tcaaaaaatt cgtagccgta ttgatggcaa ggtctggcaa
      421 ctgcctgcgg cagtttatgg ccgaatggtc aatcttgagc cagacatgac catcagcaag
      481 aacgagatgg tgaagctgct ggaggcgacc cagtatcgtc aggtgtcgaa aatgacccgt
      541 cctggcgaat ttaccgtgca ggccaacagc attgagatga ttcgccgtcc gtttgatttc
      601 ccggacagta aagaaggaca ggtgcgcgcg cgtctgacct ttgatggcga tcatctggcg
      661 acgatcgtca atatggagaa caaccgtcag ttcggtttct tccgtcttga tccgcgtctg
      721 atcaccatga tctcttcgcc aaacggtgag cagcgtctgt ttgtgccgcg cagtggtttc
      781 ccggatttgc tggtggatac tttgctggcg acagaagacc gtcattttta cgagcatgat
      841 ggaatcagtc tctactcaat cggacgtgcg gtgctggcaa acctgaccgc cggacgcacg
      901 gtacagggtg cgagtacgct gacgcaacag ctggtgaaaa acctgttcct ctccagcgag
      961 cgttcttact ggcgtaaagc gaacgaagct tacatggcgc tgatcatgga cgcgcgttac
     1021 agcaaagacc gtattcttga gctgtatatg aacgaggtgt atctcggtca gagcggcgac
     1081 aacgaaatcc gcggcttccc gctggcaagc ttgtattact ttggtcgccc ggtagaagag
     1141 ctaagcctcg accagcaggc gctgttagtc ggtatggtga aaggggcgtc catctacaac
     1201 ccgtggcgta acccaaaact ggcgctggag cgacgtaatc tggtgctgcg tctgctgcaa
     1261 cagcaacaga ttattgatca agaactctat gacatgttga gtgcccgtcc gctgggggtt
     1321 cagccgcgcg gtggggtgat ctctcctcag ccagccttta tgcaactggt gcgtcaggag
     1381 ctgcaggcaa aactgggcga taaggtaaaa gatctctccg gcgtgaagat cttcactacc
     1441 tttgactcgg tggcccagga cgcggcagaa aaagccgccg tggaaggcat tccggcactg
     1501 aagaaacagc gtaagttgag cgatcttgaa actgcgattg tggtcgtcga ccgctttagt
     1561 ggtgaagttc gtgcgatggt cggaggttct gagccgcagt ttgcgggcta caaccgtgcg
     1621 atgcaggcgc gtcgttcgat tggttccctt gcaaaaccag cgacttatct gacggcctta
     1681 agccagccga aaatctatcg tctgaatacg tggattgcgg atgcgccaat tgcgctgcgt
     1741 cagccgaatg gccaggtctg gtcaccgcag aatgatgacc gtcgttatag cgaaagcggc
     1801 agagtgatgc tggtggatgc gttgacccgt tcgatgaacg tgccgacggt aaatctgggg
     1861 atggcgctgg ggctgcctgc ggttacggag acctggatta aactgggcgt accgaaagat
     1921 cagttgcatc cggttccggc aatgctgctg ggggcgttga acttaacgcc aatcgaagtg
     1981 gcgcaggcat tccagaccat cgccagcggt ggtaaccgtg caccgctttc tgcgctgcgt
     2041 tcggtaatcg cggaagatgg caaagtgctg tatcagagct tcccgcaggc ggaacgcgct
     2101 gttccggcgc aggcggcgta tctgacacta tggaccatgc agcaggtggt acaacgcggt
     2161 acgggtcgtc agcttggggc gaaatacccg aacctgcatc tggcagggaa aacagggact
     2221 accaacaata acgtagatac ctggtttgcg ggcattgacg gcagcacggt gaccatcacc
     2281 tgggtcggcc gtgataacaa ccagccgacc aaactgtatg gtgccagcgg ggcaatgtcg
     2341 atttatcagc gttatctggc taaccagacg ccaacgccgc tgaatcttgt tccgccagaa
     2401 gatattgcag atatgggcgt ggactacgac ggcaactttg tttgcagcgg tggcatgcgt
     2461 atcttgccgg tctggaccag cgatccgcaa tcgctgtgcc agcagagcga gatgcagcag
     2521 cagccgtcag gcaatccgtt tgatcagtct tctcagccgc agcaacagcc gcaacagcaa
     2581 cctgctcagc aagagcagaa agacagcgac ggtgtagccg gttggatcaa ggatatgttt
     2641 ggtagtaatt aacatctaag cgtgaaatac cggatggcga gttgccatcc ggtaaaataa
     2701 catcccatct aagatattaa ccctttcttt tcatctggtt gtttattaac ccttcaggaa
     2761 cgctcagatt gcgtaccgct tgcgaacccg ccagcgtttc gaatattatc ttatctttat
     2821 aataatcatt ctcgtttacg ttatcattca ctttacatca gagatatacc aatggcgcgt
     2881 tccaaaactg ctcagccaaa acactcactg cgtaaaatcg cagttgtagt agccacagcg
     2941 gttagcggca tgtctgttta tgcacaggca gcggttgaac cgaaagaaga cactatcacc
     3001 gttaccgctg cacctgcgcc gcaagaaagc gcatgggggc ctgctgcaac tattgcggcg
     3061 cgacagtctg ctaccggcac taaaaccgat acgccgattc aaaaagtgcc acagtctatt
     3121 tctgttgtga ccgccgaaga gatggcgctg catcagccga agtcggtaaa agaagcgctt
     3181 agctacacgc cgggtgtctc tgttggtacg cgtggcgcat ccaacaccta tgaccacctg
     3241 atcattcgcg gctttgcggc agaaggccaa agccagaata actatctgaa tggcctgaag
     3301 ttgcagggca acttctataa cgatgcggtc attgacccgt atatgctgga acgcgctgaa
     3361 attatgcgtg gcccggtttc cgtgctttac ggtaaaagca gtcctggcgg cctgttgaat
     3421 atggtcagca agcgtccgac caccgaaccg ctgaaagaag ttcagtttaa agccggtact
     3481 gacagcctgt tccagactgg ttttgacttt agcgattcgt tggatgatga cggtgtttac
     3541 tcttatcgcc tgaccggtct tgcgcgttct gccaatgccc agcagaaagg gtcagaagag
     3601 cagcgttatg ctattgcacc ggcgttcacc tggcgtccgg atgataaaac caattttacc
     3661 ttcctttctt acttccagaa cgagccggaa accggttatt acggctggtt gccgaaagag
     3721 ggaaccgttg agccgctgcc gaacggtaag cgtctgccga cagactttaa tgaaggggcg
     3781 aagaacaaca cctattctcg taatgagaag atggtcggct acagcttcga tcacgaattt
     3841 aacgacacct ttactgtgcg tcagaacctg cgctttgctg aaaacaaaac ctcgcaaaac
     3901 agcgtttatg gttacggcgt ctgctccgat ccggcgaatg cttacagcaa acagtgtgcg
     3961 gcattagcgc cagcggataa aggccattat ctggcacgta aatacgtcgt tgatgatgag
     4021 aagctgcaaa acttctccgt tgatacccag ttgcagagca agtttgccac tggcgatatc
     4081 gaccacaccc tgctgaccgg tgtcgacttt atgcgtatgc gtaatgacat caacgcctgg
     4141 tttggttacg acgactctgt gccactgctc aatctgtaca atccggtgaa taccgatttc
     4201 gacttcaatg ccaaagatcc ggcaaactcc ggcccttacc gcattctgaa taaacagaaa
     4261 caaacgggcg tttatgttca ggatcaggcg cagtgggata aagtgctggt caccctaggc
     4321 ggtcgttatg actgggcaga tcaagaatct cttaaccgcg ttgccgggac gaccgataaa
     4381 cgtgatgaca aacagtttac ctggcgtggt ggtgttaact acctgtttga taatggtgta
     4441 acaccttact tcagctatag cgaatcgttt gaaccttctt cgcaagttgg gaaggatggt
     4501 aatattttcg caccgtctaa aggtaagcag tatgaagtcg gcgtgaaata tgtaccggaa
     4561 gatcgtccga ttgtagttac tggtgccgtg tataatctca ctaaaaccaa caacctgatg
     4621 gcggaccctg agggttcctt cttctcggtt gaaggtggcg agatccgcgc acgtggcgta
     4681 gaaatcgaag cgaaagcggc gctgtcggcg agtgttaacg tagtcggttc ttatacttac
     4741 accgatgcgg aatacaccac cgatactacc tataaaggca atacgcctgc acaggtgcca
     4801 aaacacatgg cttcgttgtg ggctgactac accttctttg acggtccgct ttcaggtctg
     4861 acgctgggca ccggtggtcg ttatactggc tccagttatg gtgatccggc taactccttt
     4921 aaagtgggaa gttatacggt cgtggatgcg ttagtacgtt atgatctggc gcgagtcggc
     4981 atggctggct ccaacgtggc gctgcatgtt aacaacctgt tcgatcgtga atacgtcgcc
     5041 agctgcttta acacttatgg ctgcttctgg ggcgcagaac gtcaggtcgt tgcaaccgca
     5101 accttccgtt tctaatttct cttttggggc acggatttcc gtgcccattt cacaagttgg
     5161 ctgttatgca ggaatacacg aatcattccg ataccacttt tgcactgcgt aatatctcct
     5221 ttcgtgtgcc cgggcgcacg cttttgcatc cgctgtcgtt aacctttcct gccgggaaag
     5281 tgaccggtct gattggtcac aacggttctg gtaaatccac tctgctcaaa atgcttggcc
     5341 gtcatcagcc gccgtcggaa ggggagattc ttcttgatgc ccaaccgctg gaaagctgga
     5401 gcagcaaagc gtttgcccgc aaagtggctt atttgccgca gcagcttcct ccggcagaag
     5461 ggatgaccgt gcgtgaactg gtggcgattg gtcgttaccc gtggcatggc gcgctggggc
     5521 gctttggggc ggcagatcgc gaaaaagtcg aggaagctat ctcgctggtt ggcttaaaac
     5581 cgctggcgca tcggctggtc gatagtctct ctggcggcga acgtcagcgg gcgtggatcg
     5641 ccatgctggt ggcgcaggat agccgttgtc tgttgctcga cgaaccgacc tcggcgctgg
     5701 atatcgccca ccaggttgat gtgctgtcgc tggtgcaccg tttaagtcag gagcgtggcc
     5761 tgacggtcat tgccgtgttg cacgatatca atatggcggc acgctactgt gattatctgg
     5821 tcgccctgcg cggcggtgaa atgattgctc agggaacgcc tgcggaaatt atgcgcggcg
     5881 aaaccctcga aatgatttat ggcatcccga tgggtatttt gccgcatccg gcgggtgctg
     5941 cacctgtgag ttttgtttat tgatgagcgg cttacctctt atttcgcgcc gtcgactgtt
     6001 aacggcgatg gcgctttctc cgttgttatg gcagatgaat accgcccacg cggcggctat
     6061 tgatcccaat cgtattgtgg cgctggagtg gttgccggtg gaattactgc tggcgctcgg
     6121 catcgtgcct tacggcgtgg cggataccat caactatcgc ctgtgggtca gcgaaccacc
     6181 attgccggac tcagtgatcg acgtcggttt gcgcacagaa cctaaccttg aactgctgac
     6241 cgaaatgaaa ccatcgttta tggtctggtc ggcaggatat ggcccttcac cagaaatgct
     6301 ggctcgtatt gcgccgggtc gcggatttaa cttcagtgac ggcaaacagc cgttggcgat
     6361 ggcgcgtaaa tcgctgacgg aaatggcaga tttacttaac ctgcaaagcg cagcggaaac
     6421 gcatttagcg caatatgaag actttatccg cagcatgaaa ccccgctttg tgaagcgtgg
     6481 tgcgcgtccg ttattgctga cgacgcttat cgatccgcgc catatgctgg tcttcggtcc
     6541 aaacagcttg ttccaggaaa ttcttgatga gtacggcatc ccaaatgcct ggcaagggga
     6601 aaccaacttc tggggcagta ccgccgtcag tatcgatcgt ctggcggcgt ataaagacgt
     6661 tgatgtgctc tgttttgatc acgacaacag caaagacatg gatgcgctaa tggcaacgcc
     6721 gctgtggcag gccatgccgt ttgtccgcgc cggacgcttt cagcgcgtac ctgcagtctg
     6781 gttttatggt gcgacgctct cggcaatgca ctttgtgcgc gttctggata acgccatcgg
     6841 aggtaaagcg tgagtaaacg aattgcgctt ttcccggcgt tattgctggc gctgttagtg
     6901 attgtcgcta cggcgctcac ctggatgaac ttctcgcagg cgctgccgcg tagccagtgg
     6961 gcgcaggctg cctggtcgcc ggatattgac gtcatcgagc agatgatttt tcactacagc
     7021 ttgttgccgc gtctggtgat ttcgctgctg gtgggcgcgg gtctggggct ggtgggcgtg
     7081 ctgtttcagc aagtgctgcg taacccgctg gcggagccga cgacgcttgg cgttgctaca
     7141 ggcgcgcaac tggggattac cgtcactacg ctctgggcga tccctggtgc gatggcgagc
     7201 cagtttgctg cgctggcagg ggcttgtgtt gttggcttaa ttgtctttgg cgtcgcgtgg
     7261 gggaaacggc tgtcgccggt aacgctgatt ctcgcggggt tggtagtgag cctttattgc
     7321 ggcgcaatca atcagttact ggttatcttc catcatgacc aactgcaaag catgtttctg
     7381 tggagcactg gaacgctgac gcaaaccgac tggggcggcg ttgagcgttt atggccgcag
     7441 ctgctgggcg gtgtgatgct gacgttgctg ctacttcgtc cgttaaccct gatggggctt
     7501 gatgatggcg tggcgcgcaa tctcgggctg gccttgtcgc ttgcgcgtct ggcggcgctg
     7561 tcgctggcga ttgtcatcag tgcgctgctg gtgaacgctg tggggattat cggctttatc
     7621 gggttgttcg cgccgctgct ggcaaaaatg ctgggggcgc ggcgtctgct gccacgactg
     7681 atgctggcgt cgttgattgg tgcgctgatc ctctggcttt ccgatcaaat catcctctgg
     7741 ctgactcgcg tgtggatgga agtgtccacc ggttcggtca ctgcgttgat cggtgcgccg
     7801 ctgctactgt ggctgttgcc gcgtttacgc agcattagcg cgccggatat gaaggtcaac
     7861 gatcgtgtcg cggctgaacg ccaacatgtg ctggcgtttg ccctcgcggg cggcgtgctg
     7921 ctgttgatgg ctgtggtggt ggcgctgtcg tttggtcgtg atgcgcacgg ctggacgtgg
     7981 gcgagcgggg cgttgctcga ggatttaatg ccctggcgct ggccgcgaat tatggcggcg
     8041 ctgtttgcgg gcgtcatgct ggcggtggcg ggctgtatta ttcagcgact gaccggaaac
     8101 ccgatggcaa gcccggaagt gctggggatt agctccggcg cggcgtttgg cgtggtgttg
     8161 atgctgtttc tggtgccggg taatgccttt ggctggctgt tacctgcagg cagtctcggc
     8221 gcggcggtga cgctgttgat cattatgatc gccgccggcc gcagtggatt ttccccacac
     8281 cgtatgttac tggcggggat ggcgttaagc accgcgttca ccatgctttt gatgatgttg
     8341 caggcaagtg gtgacccgcg aatggcgcaa gtgctgacct ggatttccgg ttcgacctac
     8401 aacgcgaccg atgcgcaggt ctggcgcacc ggaattgtga tggtgatttt gctggcgatt
     8461 accccgctgt gccgccgctg gctgaccatt ttaccgctgg gtggtgatac cgcccgagcc
     8521 gtaggaatgg cgctgacgcc gacgcgaatt gcgctgctgc tgttagcggc ttgcctgacg
     8581 gcgaccgcga cgatgactat tggaccgttg agttttgttg gtttaatggc accgcatatt
     8641 gcgcggatga tgggctttcg acggacgatg ccacacatcg taatttcggc gctggtgggt
     8701 ggtttactgc tggtgttcgc tgactggtgt gggcggatgg tgctgtttcc attccagatc
     8761 ccggcggggc tgctgtcaac ctttatcggc gcgccatatt ttatctattt gttgagaaag
     8821 cagagccgtt aatttttcca tataacggcc ctgtacgcct ggacggataa agcgtttacg
     8881 cgacaacgga tgcccgatgc gacgctggcg cgtcttatcg ggcctacaaa cggccccgaa
     8941 tcgtaggtcg gataaggcgt tcacgccgca tccgacaaac catgctggat cacaacttcg
     9001 caaacacccg acgtgcagca tcgatggtgt tattgatatc ttccatgctg tgcgccacgg
     9061 acataaagcc cgcttcaaac gctgacggtg ccaggtaaac accttcgtcc agcatcatat
     9121 ggaagaaacg cttaaagcgt tccacgtcac aggccatcac atcctgatag cacgtcacgg
     9181 actcggcgtc ggtaaagaaa ataccgaaca tgccgccaac gtggttaacg accagcggaa
     9241 ttccggcttc ttctgccgct tccagcagac cttctgccag acgtgttgtc agctcatcca
     9301 gcgtttcgtg aacgcccggc tgcgcgactt cattcagaca ggcgaaaccc gctgccatcg
     9361 caatcgggtt accggaaagc gtacccgcct gatagaccgg acccgtcggg gccagcgcat
     9421 ccattacatc acgacgacca ccgaatgcgc ctaccggcat tccaccgccg atgattttgc
     9481 cgaggcaggt taaatctggc actacgccgt aataatcctg tgcgccagct agcgctacgc
     9541 ggaaaccggt catcacttca tcgatgatca gcaacgtgcc aaattcgtcg cacagcgcgc
     9601 gcagacctgg caggaactct ggcagcggcg gaacacagtt catattgcct gccaccggct
     9661 cgacgataat acaggcaatc tcttgcgggt attgctcaaa tgcggcgcgt acagaagcca
     9721 gatcattata agtacaggtt aaggtatgtt tggcgaaatc tgccggaacg cccggcgagt
     9781 ttggctggcc taacgtgagt gcgccagaac cggctttcac cagcaggcag tcagcgtgac
     9841 catggtaaca cccttcaaat ttaataattt tgtcgcgacc ggtaaaacca cgggccaggc
     9901 ggatggcgct catggtcgct tcagtgccgg agttcaccat gcgcaccata tccatggtcg
     9961 ggaccagttc ggtcaccagt tgcgccattt tcacttccat ttcggttggt gcaccaaagc
    10021 ttaaaccacg ctcggcggct tcaatcacgg cattgcggat tgccggatgg ttatggccca
    10081 gcaccatcgg cccccaggaa ccgacataat cgatataggc tttgccatca acatcgtaca
    10141 gataagcgcc gtccgctttt tcgataaaca gtggagtgcc gcccacgcca gtaaaggcgc
    10201 gaacagggga gttcacaccg ccagggatca gctcgcgcgc tgcgctgtaa agattttcag
    10261 acttactcat ggagggttcc tgattcgtag aaaaagtgaa tggctgctat tctatgttat
    10321 tcataacaag ttaaatactc gtcaaacatc aggctgcttg tactggtgca atcctgattt
    10381 cttagagtat aaaagttttg tgcatttgaa acattacgct ttgcaaagga ttttcatgga
    10441 acgtgcgagt aaaatgccgt catcttattt gtatgaccaa taagtgatca ttggatgaaa
    10501 actgatactc cctctttaga aacaccgcag gccgcgcgcc tgcgacgcag acaactgatt
    10561 cgccaacttc ttgagcgcga taaaaccccg ttagccattt tgtttatggc ggcagtcgtc
    10621 ggcacgcttg ttgggctggc agcggttgct tttgacaaag gtgtcgcctg gttgcagaac
    10681 caacgtatgg gggcgctggt acatactgct gataattatt cgcttctgtt aaccgtcgct
    10741 tttctctgtt cggcggtgct ggcgatgttt ggctactttt tggtgcgcaa atacgcgccg
    10801 gaagcaggtg gttcggggat cccggaaatt gaaggggcgc tggaagatca acgtcccgtt
    10861 cgctggtggc gtgtattgcc ggtgaagttc tttggcgggc tggggacact cggcggaggc
    10921 atggtgttgg ggcgcgaagg gccaaccgtg cagatcggcg gtaacattgg ccgtatggtg
    10981 cttgatattt tccgcctgaa aggtgacgaa gctcgccata cgctgctggc aaccggtgct
    11041 gctgcggggc tggctgcggc ctttaacgcg ccgctggcgg gtattttgtt tattatcgaa
    11101 gagatgcgtc cgcagtttcg ctatacgtta atttcgatta aagcggtatt tattggtgtc
    11161 attatgtcga ccattatgta ccggattttt aatcatgaag ttgcgttgat tgacgtcggt
    11221 aaactttctg atgcgccgct taatacgctg tggctttatc tgatcctcgg tattattttt
    11281 ggcattttcg gccctatttt taataaatgg gtgctgggga tgcaggattt gctgcaccgt
    11341 gtgcacggcg gcaatattac caaatgggtg ctaatgggcg gtgcgattgg cggtctgtgt
    11401 ggattgctgg ggtttgtggc accagcaacg tcgggcggcg gttttaacct gattcctatc
    11461 gctaccgcgg ggaatttcag catgggaatg ctggtgttta tcttcgtcgc gcgggtcatt
    11521 accaccttac tctgcttctc ttccggcgcg ccgggcggta tttttgcccc gatgctggcg
    11581 ctgggtactg tgctgggaac cgctttcgga atggttgccg ttgagctgtt tccgcaatat
    11641 caccttgagg cggggacgtt tgctattgcc ggaatggggg cattactggc ggcatctatt
    11701 cgcgcgccgt taacggggat cattctggtt ctggagatga ccgataacta ccagctcatt
    11761 ttgccaatga ttattaccgg tcttggcgca acactattag cgcaatttac cggcgggaaa
    11821 ccgctatact cggcgattct tgcgcgcacg ctggcaaaac aggaagctga gcaactggcg
    11881 cgaagcaagg ccgcatcagc cagcgagaat acttgaacga aataccaggg tattagataa
    11941 tggcgattat tattgggtta gaatttgccc aattgccgat gtcgtttgga gcaaaatatg
    12001 agtgatgacg tagcactgcc gctggagttt accgacgcag cagccaacaa agttaaaagc
    12061 ctgatcgctg acgaagataa cccgaatctg aaattacgcg tgtatatcac cggtggcggt
    12121 tgcagcggct tccagtatgg tttcaccttt gatgatcagg tgaacgaagg cgatatgacc
    12181 atcgaaaaac agggcgttgg cctggtggtt gatccgatga gcctgcaata tctggtcggc
    12241 ggttccgttg attataccga aggtctggaa ggttctcgtt tcatcgtgac caacccgaac
    12301 gcgaaaagca cctgcggttg cggttcttcc tttagtatct aatctgttgt tcatgtgccg
    12361 gataaactat ccggcacatc ttctctcttc aacgcccatt ctcatccagc gcaaacgtcg
    12421 gtagcttaag atgccaacga atagccgcca gccgaatcaa tagcgtcacg accatgccca
    12481 tcatactggc tgtttccagt ggtacggaaa atgtgtaata agccgtagcg tggacaatac
    12541 cgccgataat acaggcagtt gcgtagattt ctgtacgtaa aatcatgggg atttcgcggg
    12601 ccagaacatc acgaatgatc ccgccgccaa cgccagtaat gacgcccata caaaccgcga
    12661 ttaacggacc ggcttccgca ttaaaggctt tattcacgcc aatgccgaca aacaccgcca
    12721 gaccaacggc gtccagcacc ggcaacatcc attttggtaa gcgtcttggc tggcgcacca
    12781 gcacgatggt cagcatgctg gtgaccattg caacgaccag atcggtggga tctttcaccc
    12841 aaaataccgg gccgtgatcc agcgccatgt cgcgaattgt cccgccgcct actgcggtta
    12901 ccacgcccag taccagaaca ccaaaagggt ccatacgcaa ttttccggct aacaaaacgc
    12961 cggagatggc aaataccgct gtgccgacta tatccagcca atagacgagc attgttcaat
    13021 ccccactgag cacctgaaaa ggtcaggcgc taatctacct gtgaaagcgc attacagagc
    13081 tgttgtgcag cgaggataat acgtgggctt gcacgttcaa accagtcact cgtgagagga
    13141 ataacgggaa ttttgagctg ttcaccccag tattgtttga ttttaggaat ttggtccggt
    13201 ccgcctgtaa tgacaatcgc ctgtggcgag cgtgctaaca cctgttcgcg gctaacttgc
    13261 ggccagggaa cccggctgtc tttaaagatg ttttctccgc cacaaacttc gagtacctgg
    13321 ttctgaatcg actcttttcc actggtaaat ggcggattaa tgccgaattg cagaaaaaca
    13381 cgttttttag gtttatcagc atattgcgct ttcaattgcg cgtactgatc cagcagggat
    13441 tgcgcggctt gttcggcctt gtctggttgc ggactccagg gggccagttg acgtaacgca
    13501 ttggcaattt gttcaatgct tgtcgcatcg acccacatca cttttattcc cagcgaagcc
    13561 agctggtcaa cctgccgctc ggcattacct ccacgccagg caatcaccag atcgggtttc
    13621 agcgcgacaa tgcgttccag attcatcccc tgccaggtgg aaacctgctc aatcttttgc
    13681 gcttgtggag gatagtcgga atagctgctg accccaaccg gcgtgatccc ggcggcaaag
    13741 gcaagttcag tgttggcggg agaaagcgtg atgacgcgcg gcgcggcgtt gagccacagt
    13801 ggcgcaagaa aagacagggc gaccagcgcc ctgaacagtg acttagccat gtgcaagttt
    13861 ctgcaccagt gactcaacca tcaggctgga ctgtttagcg gcaacagcca ggaactcatc
    13921 gaagctaaga tgagactgtt gatcggccac gtcggagatg gcgcgtacga caacaaacgg
    13981 gacgttgaaa ttgtggcaga catgggcgat tgccgtcgct tccatctcta cagcaatggc
    14041 ctgtgggaag ttgtggcgga ttttcgccag accaacagaa ccgttgatga aagcgtcgcc
    14101 gctaacaatc aggccacgta cagcgttaag attcagttcg gcaatgcagg cctcagcggc
    14161 agcgatcagt ttatcgtcag ctttaaagcc tgccggacag cctggtaact gaccgtattc
    14221 ataaccaaat gccgtgacat ccgcgtcgtg ataacgtgct tcgtccgaga caacgatatc
    14281 gcccactttc aacgttggtg ccaggccacc ggcagaaccg gtgttaataa tcacatctgg
    14341 cttgcagtgt tccaacagca aagtggcacc cagcgccgca gcgactttac cgatgcccga
    14401 tttcagaagc gcaacctcgg ttccattcag ttggccggta tagatttcgc aaccgccgag
    14461 actgatagtt tgacggtttt cgattttgtc acgcagcagc gtaacttctt cttccattgc
    14521 accaatgatg ccgattttca tagatttact cgcgataagc ccgatttgaa ggcatagttt
    14581 accatgcgct tacggggaag cgtatttctc acgcgggaga ggacatggca cagattgatt
    14641 tccgaaaaaa aataaactgg catcgtcgtt accgttcacc gcagggcgtt aaaaccgaac
    14701 atgagatcct gcggatcttc gagagcgatc gcgggcgtat catcaactct ccggcaattc
    14761 gtcgtctgca acaaaagacc caggtttttc cactggagcg caatgccgcc gtgcgcacgc
    14821 gtcttaccca ctcgatggaa gtccagcagg tggggcgcta catcgccaaa gaaattttaa
    14881 gccgtctgaa agagcttaaa ttactggaag catacggcct ggatgaactg accggtccct
    14941 ttgaaagcat tgttgagatg tcatgcctga tgcacgatat cggcaatccg ccgtttggtc
    15001 attttggcga agcggcgata aatgactggt ttcgccaacg tttgcacccg gaagatgccg
    15061 aaagccagcc tctgactgac gatcgctgca gcgtggcggc actacgttta cgggacgggg
    15121 aagaaccgct taacgagctg cggcgcaaga ttcgtcagga cttatgtcat tttgagggga
    15181 atgcacaagg cattcgcctg gtgcatacat tgatgcggat gaatctcacc tgggcacagg
    15241 ttggcggtat tttaaaatat acccgtccgg cgtggtggcg tggcgaaacg cctgagacac
    15301 atcactattt aatgaaaaag ccgggttatt atctttctga agaagcctat attgcccggt
    15361 tgcgtaaaga acttaatttg gcgctttaca gtcgttttcc attaacgtgg attatggaag
    15421 ctgccgacga catctcctat tgtgtggcag accttgaaga tgcggtagag aaaagaatat
    15481 ttaccgttga gcagctttat catcatttgc acgaagcgtg gggccagcat gagaaaggtt
    15541 cgctcttttc gctggtggtt gaaaatgcct gggaaaaatc acgctcaaat agtttaagcc
    15601 gcagtacgga agatcagttt tttatgtatt tacgggtaaa caccctaaat aaactggtac
    15661 cctacgcggc acaacgattt attgataatc tgcctgcgat tttcgccgga acgtttaatc
    15721 atgcattatt ggaagatgcc agcgaatgca gcgatcttct taagctatat aaaaatgtcg
    15781 ctgtaaaaca tgtgtttagc catccagatg tcgagcagct tgaattgcag ggctatcggg
    15841 tcattagcgg attattagag atttatcgtc ctttattaag cctgtcgtta tcagacttta
    15901 ctgaactggt agaaaaagaa cgggtgaaac gtttccctat tgaatcgcgc ttattccaca
    15961 aactctcgac gcgccatcgg ctggcctatg tcgaggctgt cagtaaatta ccgtcagatt
    16021 ctcctgagtt tccgctatgg gaatattatt accgttgccg cctgctgcag gattatatca
    16081 gcggtatgac cgacctctat gcgtgggatg aataccgacg tctgatggcc gtagaacaat
    16141 aaccaggctt ttgtaaagac gaacaataaa tttttacctt ttgcagaaac tttagttcgg
    16201 aacttcaggc tataaaacga atctgaagaa cacagcaatt ttgcgttatc tgttaatcga
    16261 gactgaaata catgaaaaaa accacattag cactgagtgc actggctctg agtttaggtt
    16321 tggcgttatc tccgctctct gcaacggcgg ctgagacttc ttcagcaacg acagcccagc
    16381 agatgccaag ccttgcaccg atgctcgaaa aggtgatgcc ttcagtggtc agcattaacg
    16441 tagaaggtag cacaaccgtt aatacgccgc gtatgccgcg taatttccag cagttcttcg
    16501 gtgatgattc tccgttctgc caggaaggtt ctccgttcca gagctctccg ttctgccagg
    16561 gtggccaggg cggtaatggt ggcggccagc aacagaaatt catggcgctg ggttccggcg
    16621 tcatcattga tgccgataaa ggctatgtcg tcaccaacaa ccacgttgtt gataacgcga
    16681 cggtcattaa agttcaactg agcgatggcc gtaagttcga cgcgaagatg gttggcaaag
    16741 atccgcgctc tgatatcgcg ctgatccaaa tccagaaccc gaaaaacctg accgcaatta
    16801 agatggcgga ttctgatgca ctgcgcgtgg gtgattacac cgtagcgatt ggtaacccgt
    16861 ttggtctggg cgagacggta acttccggga ttgtctctgc gctggggcgt agcggcctga
    16921 atgccgaaaa ctacgaaaac ttcatccaga ccgatgcagc gatcaaccgt ggtaactccg
    16981 gtggtgcgct ggttaacctg aacggcgaac tgatcggtat caacaccgcg atcctcgcac
    17041 cggacggcgg caacatcggt atcggttttg ctatcccgag taacatggtg aaaaacctga
    17101 cctcgcagat ggtggaatac ggccaggtga aacgcggtga gctgggtatt atggggactg
    17161 agctgaactc cgaactggcg aaagcgatga aagttgacgc ccagcgcggt gctttcgtaa
    17221 gccaggttct gcctaattcc tccgctgcaa aagcgggcat taaagcgggt gatgtgatca
    17281 cctcactgaa cggtaagccg atcagcagct ttgccgcact gcgtgctcag gtgggtacta
    17341 tgccggtagg cagcaaactg accctgggct tactgcgcga cggtaagcag gttaacgtga
    17401 acctggaact gcagcagagc agccagaatc aggttgattc cagctccatc ttcaacggca
    17461 ttgaaggcgc tgagatgagc aacaaaggca aagatcaggg cgtggtagtg aacaacgtga
    17521 aaacgggcac tccggctgcg cagatcggcc tgaagaaagg tgatgtgatt attggcgcga
    17581 accagcaggc agtgaaaaac atcgctgaac tgcgtaaagt tctcgacagc aaaccgtctg
    17641 tgctggcact caacattcag cgcggcgaca gcaccatcta cctgttaatg cagtaatctc
    17701 cctcaacccc ttcctgaaaa cgggaagggg ttctccttac aatctgtgaa cttcaccaca
    17761 actccataca tcttcatcat cctttaggca tttgcacaat gccgtacgtt acgtacttcc
    17821 ttatgctaag ccgtgcataa cggaggactt atggctggct ggcatcttga taccaaaatg
    17881 gcgcaggata tcgtggcacg taccatgcgc atcatcgata ccaatatcaa cgtaatggat
    17941 gcccgtgggc gaattatcgg cagcggcgat cgtgagcgta ttggtgaatt gcacgaaggt
    18001 gcattgctgg tactttcaca gggacgagtc gtcgatatcg atgacgcggt agcacgtcat
    18061 ctgcacggtg tgcggcaggg gattaatcta ccgttacggc tggaaggtga aattgtcggc
    18121 gtaattggcc tgacaggtga accagagaat ctgcgtaaat atggcgaact ggtctgcatg
    18181 acggctgaaa tgatgctgga acagtcgcgg ttgatgcact tgttggcgca ggatagccgt
    18241 ttgcgggaag aactggtgat gaacctgatt caggcagagg agaatactcc cgcacttact
    18301 gaatgggcgc aacggctggg gatcgatctc aatcaaccgc gagtggtggc tattgttgag
    18361 gtcgacagcg gtcagcttgg cgtggacagc gcaatggcgg agttacaaca actgcaaaac
    18421 gcgctgacta cgcccgagcg taataatctg gtggcgattg tctcgctaac cgaaatggtg
    18481 gtgttgaaac cggcgttgaa ctcttttggg cgctgggatg cagaagatca tcgtaagcga
    18541 gttgaacaac tgattacccg catgaaagag tacggccagc tgcgttttcg cgtttcactg
    18601 ggcaactatt ttaccggtcc tggcagtatt gcccgatcct atcgtacggc gaaaacgacg
    18661 atggtggtgg gtaaacagcg gatgccagaa agtcgctgct atttttatca ggatctgatg
    18721 ttacctgtgt tactcgacag tttgcgtggc gactggcagg ccaacgaact ggcgcgaccg
    18781 ctggcgcggc tgaaaacgat ggacaataac ggcttgctgc gacgaacgct ggcggcgtgg
    18841 tttcgccaca atgtgcaacc gctggcaacg tcaaaggcgt tgtttattca tcgtaatacc
    18901 ctggagtatc ggcttaatcg tatatcggaa ctgaccgggc ttgatttggg caattttgat
    18961 gacaggttgc tgctgtatgt ggcgttacaa ctggatgaag agcggtaggt tatgcgttaa
    19021 ggttgaggcg gcgctggctc attcccctca gcccgaaggg tagaggggaa tgcccgaatt
    19081 aaccgtcagt tcgggattat ttacgcgtta gtttttccag atcggcttca atctcgctga
    19141 tcttattggt tacgactgac tccaggtgac gtaagtcgtc gaggatctta cgcttaagat
    19201 caacttcgct gcggtcacgc tggcagattt gatcaagctc atcaatgata taccgtagat
    19261 tcgggctgat ttcctggact tctttataac cctgacccac accatcagcg acgaccgttt
    19321 tacgctgacg cggatattta aacttaacgc tcttggcgaa aaactcgcct ttgtctttct
    19381 ggaaatagat tttcagaata tcgttgttgg cttcctgccg gaggctgtaa cgatcaattt
    19441 cttcaggatt ggtaataccc agacttttca gattgtcgta catagcgtta cctcaaaatg
    19501 agtcagtaaa ttgtgcttat tttagcattt ggcctggccc gcccggctcg actgtgatcg
    19561 cagaaagcct ttttcttcca gacttctatc atggcgtaaa aatcaaaaaa ttacctgctt
    19621 tattctggtg ataaaattca cgatctacac cagttccagc atcgttactt ccgggcggca
    19681 gttcagacgc aaaccataca aactgcccac gccacgggtt gtgtagatgt gtctttcgcc
    19741 aaaggcattt aatccggcga cgtaacgttt atcttcgaca ggggcaaaag gttcaccaac
    19801 caacggtacg cgcagttgcc cgccgtgagt atggccgcac agcatcagat cccagggttc
    19861 atcacgcatg acttctttgc tgtcgggatt atgcgccagc accagtcttg gcagattggc
    19921 ttcgctggcg ggaggcggtt tgcattgtcc ggcccataag tcaccagtgc ctaccagttc
    19981 gaattgcctg ttcggcgtgg cgatcaccgt agcctggtta aacaacaccg tgatgcccgc
    20041 tgatttcaac gtctcgccaa ttaagtgatt tttttctgta ccaacagggc gatcgtggtt
    20101 gccgaagcag gcaaacgtcg gcgcacattc ggcaaggggg gagagtacgt cactaaacgc
    20161 cgaaaaattc agcgacatat caaataatac gtaatcgccg cccagtaata tcaaatcggg
    20221 cttttgttct atgccaagag caatcgcgtc agaaatcagg cttaaaggaa caaaacgaga
    20281 gtaatggaga tcggccagaa aaagaatttt gaatggtgct gcgttgtctt taaaaaaggc
    20341 gaggcggtga cggattaatt caaaccagcc tggctcacag taatgcatat aaccgaaacc
    20401 tgagctcgtg gctatcgtcg cggcagtagc ctgcaaaaat cggcggcgtg aaatcatcgc
    20461 tcatccctgc aaaaaaatcg ggcagcgtcg tgctgcccgt gtgcatactt ttagtcgatg
    20521 gtacgcagca gttcgttaat gccgactttg ccgcgagttt tcgcgtcaac tttcttaacg
    20581 ataaccgcac agtagaggct gtatttgcca tcttttgacg gcagattacc tgaaacaacc
    20641 acagaccccg ccggaacgcg accgtagtgg atttcgccgg tttcacggtc gtaaatacgg
    20701 gtgctctgac caatgtatac gcccatggaa atgacggaac cttcttcgac aatcacccct
    20761 tcaaccactt cagagcgcgc gccgatgaag caattatctt caatgatggt tgggttagcc
    20821 tgcagcggtt ccagcacgcc gccgatgccc acgccaccgg aaaggtggac gtttttacca
    20881 atctgcgcac aagaaccgac ggtcgcccag gtatcaacca tggtgccttc atcaacatat
    20941 gcgccgatgt tgacgtaaga cggcatcagc acggtgttac gggcaataaa cgcaccctga
    21001 cgtaccgccg ctggtggcac aacgcggaag ccttctttct ggaaacgtgc ttcgtcgtag
    21061 tcggcgaatt tcatcggcac tttgtcgaag tagcggcttt ctgccccttc gatcacctga
    21121 ttatcattaa tacggaaaga gagcagcacc gcttttttca accactgatg cgtcacccac
    21181 tgaccgtcaa ttttttccgc tacacgcagt gcgccggaat ccagcagggc gatcacctga
    21241 tttaccgctt cgcgggtaac ggtgtctgca ttggctggcg tgatctcggc acggcgttca
    21301 aaagcggttt caataatgtt ctgtaactgc tgcattgtta aactcttttc atatcagtaa
    21361 acacatcacc ctttatcgtt tggattgagg gcctctgtca accgctgatg cacttcctgc
    21421 tgcaactcgt tattaagcgc acgccggtca gcggtggcaa ttatgaataa atcttctact
    21481 cgctcgccaa tggttgtaat tcgggcacca tgaagcgaaa ttcccagatc ggcaaaaatt
    21541 ttcccgactc gcgccagcag tccaggttgg tcgagggcga tcagttcgag gaacgatttg
    21601 cggtcggtat gggtcggcaa aaacgttact tcggtttcaa cagtaaaatg gcgtaatttg
    21661 gcaggttggc gacggggctg cggtggctgc cagctacttt gcgtcagtac ttgctccaga
    21721 ccaaaccgaa taacctcatg acgatctgcg gacagcgggt tgccatcggg ttccagcacg
    21781 ataaaggtat ccatcgccat accgtcgcga gtggtgaaaa tttgtgcgtc gtgaacactt
    21841 aaattgcggc ggtctaattc ggcacagacg gcggcaaaca gataagggcg gtccgggctc
    21901 cagataaaaa tctcggtgcc tccacgcgta gcctgcgggc taagcaatac cagcggtttg
    21961 cttaaatcat gctgtaataa atggcgggca tgccaggcca gttgatttgg gctatggcgg
    22021 acaaaatagt tagcacgaca gcgtgaccaa atttggtgca gcgcctcttc gtcgatgtta
    22081 tccatgcgca gtagtgccag tgcctggagt tggtgatggc gaacccgttc gcgcatatcc
    22141 ggcgtgtttt gcattccgcg tcgtagctgc ttttcggtgg caaagtagag ctcacgcaac
    22201 agactttgct tccagctatt ccacagcgtt tcgttggtgg cgcaaatgtc agccacagtc
    22261 aggcatacca gatagcgcag acgattttcc gtttgcactt cttcggcaaa ctgcttgatg
    22321 acttccgggt cctgaatatc gcggcgttgg gcggtcaccg acatcaacag gtgctggcga
    22381 accagccagg cgaccagctg tgtttcgcgt gagttcagcc cgtggagttc ggcaaaatgc
    22441 actacatcct gagcaccgag aatggagtgg tcgccgccgc gtcctttggc gatatcgtga
    22501 aacagcgcgg cgatgaaaat cagctcagtt gacggcaggc gcggccagac gtccacacac
    22561 aacggatggc gctggcgcgt ttcttcactg gcaaaactct ccagtttcag catcacgcgg
    22621 atagtatgtt catccaccgt gtaggcgtgg aacagatcaa actgcatctg cccgacgata
    22681 tgcgaccatt gcggcatata cgcgccgagc acgctatggc gatgcattgg caatagcccg
    22741 cgccgcaccg ctccggggtg acgcagaatg ctcaaaaaca gttttcgtgc ttccggaata
    22801 ttacacagcg gttgttgcag atggcgacgg gcatggcgta actggcgcag cgtggtggag
    22861 taaatgccgg tgatcgcact gttgtgcacc atggtgtaga acatacgcaa gatggcttcc
    22921 ggctggcgca taaatagtgt ttcatcacgc aggtcgatta gcgtaccgcg tagctgaaac
    22981 tcatcgtcga ttggacgtgg tttttcgtcg gcgggaaggg cgaggatggc ttcatcgaac
    23041 agttgcagca gcatctggtt gagttcactg acgcggcgtg taacgcggaa gtaatccttc
    23101 atcatccgct cgaccggttc gttaccttca ccactgtaat tcagacgctg ggcgacgcta
    23161 agctggcgat cgaataacag gcgattatcg taacggctga cgaccagatg cagggcaaag
    23221 cgaatacgcc acaatatatg cagacattcg tttaattccg cccgctccgc tgaggttaag
    23281 aagccaaacc cgaccatttc atccagcgat gttgcgccaa aatgacggcg ggccacccat
    23341 tgcagagtgt ggatatcgcg caagccgcca gggctgcttt tgatgtctgg ttcaaggttg
    23401 tagctggtgc catggtaacg ctgatggcgc tggttctgtt cttcaacttt cgccgcgtag
    23461 aacttgtcgg aaggccagaa tccttcgctg aaaatatgtt tttgcagttc gaggaacagc
    23521 gcaacatcgc caattaataa gcgggattcg attaaattgg tggcgacggt taaatccgat
    23581 aacccttcca gcatgcactc ttcaagcgtg cgcacgctat gaccgacttc cagctttaca
    23641 tcccagagca gcgttaacag ctcgcccact ttttgcgcct gatcgtccgg gagcttttta
    23701 cggcttaaaa tcagtaaatc gacgtctgaa agtggatgca gctcgccacg accgtagcca
    23761 ccgacggcga ccaatgccag gtcggcaatc tggctgaatc ccgcttcaat ccataatcgt
    23821 tgcaggagct ggtcgataaa ctcggtgcgc gcctcaatca actgttctgc agagatccca
    23881 ttgtcaaagg catcacccag ccaacgctgg aaagtatcga tatgggcttt tatcccaccg
    23941 acggttaatt catcacgggg ccagacgcat ggattttgcg gttgaccggg cagggtgggg
    24001 agagcggtgt ttgcgtactg ttctggaagg gtattcattg tgcgccaccc ataagattaa
    24061 attatcgcat taaaaaagcc ggcattcgcc ggcttcatct tattcgtcgt gcgagattat
    24121 cgccgggatg gtgtcatcct tgcgtagcgt cagaatttcg cagccgttat cagtcaccac
    24181 aatagtatgc tcatattgtg cagacaagct gcgatctttg gtttttaccg tccagccatc
    24241 tttcatggtg cggatctctt ttttacccgc gttgaccatt ggctcgatgg tgaacgtcat
    24301 cccaggtttc agtacgacgt tggtttcacg ggagtcatag tgcagcacct gcggttcttc
    24361 atggaagccg cgaccaatac cgtgtccgca atattcacga acgacggaga agccttctgc
    24421 ttcgacaaat ttctgaatcg ccgcaccgat ttcgcgcaga ttaatgcctg gttttaccat
    24481 gcgtagcgcc aggtacaggc tttcttgcgt gatgcggcac agacgttcgc ccatgatggt
    24541 cggcttaccg acgataaaca ttttcgaggt atcgccgtgg aaaccatctt tgattacggt
    24601 gacatcaatg ttaacgatat cgccatcttt cagcagctta gcatcgtccg ggataccgtg
    24661 gcacaccact tcattaatag agatgcaaac ggatttcgga tagccgtgat agccgaggca
    24721 ggcagaaacc gcgtgttgtt cattaacaat gtaatcatta cagatgcgat ccagctcgcc
    24781 ggtgctgacg cccggtttaa catacggttc gatcatctcc agcacttcgg cagccagtcg
    24841 gccagcgacg cgcatttttt cgatatcttc tggggtcttg attgagatag ccattaattc
    24901 tgtccatcag cgtcggtgat accgacaata tatatgtaag tgccgtcaat ggtatcacac
    24961 ccgggcaaat tgagaatcat tctgaatttc gccaaacgtg ccactgaagg ttttctataa
    25021 tagaaaattc gacgtctgat gctgtacaca gcgccaacaa ttattggtgt ccacgacgta
    25081 tttgtggtat aaagcgcgcc ggacttccga tccatttcgt atacacagac tggacggaag
    25141 cgacaatctc actttgtgta acaacacaca cgtatcggca catattccgg ggtgcccttt
    25201 ggggtcggta atatgggata tgtggaggca taaccccaac ttttatatag aggttttaat
    25261 catggcaact gtttccatgc gcgacatgct caaggctggt gttcacttcg gtcaccagac
    25321 ccgttactgg aacccgaaaa tgaagccgtt catcttcggt gcgcgtaaca aagttcacat
    25381 catcaacctt gagaaaactg taccgatgtt caacgaagct ctggctgaac tgaacaagat
    25441 tgcttctcgc aaaggtaaaa tccttttcgt tggtactaaa cgcgctgcaa gcgaagcggt
    25501 gaaagacgct gctctgagct gcgaccagtt cttcgtgaac catcgctggc tgggcggtat
    25561 gctgactaac tggaaaaccg ttcgtcagtc catcaaacgt ctgaaagacc tggaaactca
    25621 gtctcaggac ggtactttcg acaagctgac caagaaagaa gcgctgatgc gcactcgtga
    25681 gctggagaaa ctggaaaaca gcctgggcgg tatcaaagac atgggcggtc tgccggacgc
    25741 tctgtttgta atcgatgctg accacgaaca cattgctatc aaagaagcaa acaacctggg
    25801 tattccggta tttgctatcg ttgataccaa ctctgatccg gacggtgttg acttcgttat
    25861 cccgggtaac gacgacgcaa tccgtgctgt gaccctgtac ctgggcgctg ttgctgcaac
    25921 cgtacgtgaa ggccgttctc aggatctggc ttcccaggcg gaagaaagct tcgtagaagc
    25981 tgagtaataa ggcttgataa ctcccccaaa atagttcgag ttgcagaaag gcggcaagct
    26041 cgagaattcc cgggagctta catcagtaag tgaccgggat gagcgagcga agataacgca
    26101 tctgcggcgc gaaatatgaa gggggagagc ccttatagac caggtagtac acgtttggtt
    26161 agggggcctg catatggccc cctttttcac ttttatatct gtgcggttta atgccgggca
    26221 gatcacatct ccgaggattt tagaatggct gaaattaccg catccctggt aaaagagctg
    26281 cgtgagcgta ctggcgcagg catgatggat tgcaaaaaag cactgactga agctaacggc
    26341 gacatcgagc tggcaatcga aaacatgcgt aagtccggtg ctattaaagc agcgaaaaaa
    26401 gcaggcaacg ttgctgctga cggcgtgatc aaaaccaaaa tcgacggcaa ctacggcatc
    26461 attctggaag ttaactgcca gactgacttc gttgcaaaag acgctggttt ccaggcgttc
    26521 gcagacaaag ttctggacgc agctgttgct ggcaaaatca ctgacgttga agttctgaaa
    26581 gcacagttcg aagaagaacg tgttgcgctg gtagcgaaaa ttggtgaaaa catcaacatt
    26641 cgccgcgttg ctgcgctgga aggcgacgtt ctgggttctt atcagcacgg tgcgcgtatc
    26701 ggcgttctgg ttgctgctaa aggcgctgac gaagagctgg ttaaacacat cgctatgcac
    26761 gttgctgcaa gcaagccaga attcatcaaa ccggaagacg tatccgctga agtggtagaa
    26821 aaagaatacc aggtacagct ggatatcgcg atgcagtctg gtaagccgaa agaaatcgca
    26881 gagaaaatgg ttgaaggccg catgaagaaa ttcaccggcg aagtttctct gaccggtcag
    26941 ccgttcgtta tggaaccaag caaaactgtt ggtcagctgc tgaaagagca taacgctgaa
    27001 gtgactggct tcatccgctt cgaagtgggt gaaggcatcg agaaagttga gactgacttt
    27061 gcagcagaag ttgctgcgat gtccaagcag tcttaattat caaaaaggag ccgcctgagg
    27121 gcggcttctt tttgtgccca tcttgtaaat tcagctaacc cttgtggggc tgcgctgaaa
    27181 agcgacgtac aatgtcgcta gtattaattc atttcaatcg ttgacagtct caggaaagaa
    27241 acatggctac caatgcaaaa cccgtctata aacgcattct gcttaagttg agtggcgaag
    27301 ctctgcaggg cactgaaggc ttcggtattg atgcaagcat actggatcgt atggctcagg
    27361 aaatcaaaga actggttgaa ctgggtattc aggttggtgt ggtgattggt gggggtaacc
    27421 tgttccgtgg cgctggtctg gcgaaagcgg gtatgaaccg cgttgtgggc gaccacatgg
    27481 ggatgctggc gaccgtaatg aacggcctgg caatgcgtga tgcactgcac cgcgcctatg
    27541 tgaacgctcg tctgatgtcc gctattccat tgaatggcgt gtgcgacagc tacagctggg
    27601 cagaagctat cagcctgttg cgcaacaacc gtgtggtgat cctctccgcc ggtacaggta
    27661 acccgttctt taccaccgac tcagcagctt gcctgcgtgg tatcgaaatt gaagccgatg
    27721 tggtgctgaa agcaaccaaa gttgacggcg tgtttaccgc tgatccggcg aaagatccaa
    27781 ccgcaaccat gtacgagcaa ctgacttaca gcgaagtgct ggaaaaagag ctgaaagtca
    27841 tggacctggc ggccttcacg ctggctcgtg accataaatt accgattcgt gttttcaata
    27901 tgaacaaacc gggtgcgctg cgccgtgtgg taatgggtga aaaagaaggg actttaatca
    27961 cggaataatt cccgtgatgg ataaataagg gtaagattcc gcgtaagtat cgcgggggcg
    28021 taagtctggt tataaggcgt tattgttgca ggcagtttgg tcacggccag cgcgcagcaa
    28081 ccggagcgta caaaagtacg tgaggatggc gagcactgcc cggggccaaa atggcaaata
    28141 aaatagccta ataatccaga cgattacccg taatatgttt aatcagggct atacttagca
    28201 cacttccact gtgtgtgact gtctggtctg actgagacaa gttttcaagg attcgtaacg
    28261 tgattagcga tatcagaaaa gatgctgaag tacgcatgga caaatgcgta gaagcgttca
    28321 aaacccaaat cagcaaaata cgcacgggtc gtgcttctcc cagcctgctg gatggcattg
    28381 tcgtggaata ttacggcacg ccgacgccgc tgcgtcagct ggcaagcgta acggtagaag
    28441 attcccgtac actgaaaatc aacgtgtttg atcgttcaat gtctccggcc gttgaaaaag
    28501 cgattatggc gtccgatctt ggcctgaacc cgaactctgc gggtagcgac atccgtgttc
    28561 cgctgccgcc gctgacggaa gaacgtcgta aagatctgac caaaatcgtt cgtggtgaag
    28621 cagaacaagc gcgtgttgca gtacgtaacg tgcgtcgtga cgcgaacgac aaagtgaaag
    28681 cactgttgaa agataaagag atcagcgaag acgacgatcg ccgttctcag gacgatgtac
    28741 agaaactgac tgatgctgca atcaagaaaa ttgaagcggc gctggcagac aaagaagcag
    28801 aactgatgca gttctgattt cttgaacgac aaaaacgccg ctcagtagat ccttgcggat
    28861 cggctggcgg cgttttgctt tttattctgt ctcaactctg gatgtttcat gaagcaactc
    28921 accattctgg gctcgaccgg ctcgattggt tgcagcacgc tggacgtggt gcgccataat
    28981 cccgaacact tccgcgtagt tgcgctggtg gcaggcaaaa atgtcactcg catggtagaa
    29041 cagtgcctgg aattctctcc ccgctatgcc gtaatggacg atgaagcgag tgcgaaactt
    29101 cttaaaacga tgctacagca acagggtagc cgcaccgaag tcttaagtgg gcaacaagcc
    29161 gcttgcgata tggcagcgct tgaggatgtt gatcaggtga tggcagccat tgttggcgct
    29221 gctgggctgt tacctacgct tgctgcgatc cgcgcgggta aaaccatttt gctggccaat
    29281 aaagaatcac tggttacctg cggacgtctg tttatggacg ccgtaaagca gagcaaagcg
    29341 caattgttac cggtcgatag cgaacataac gccatttttc agagtttacc gcaacctatc
    29401 cagcataatc tgggatacgc tgaccttgag caaaatggcg tggtgtccat tttacttacc
    29461 gggtctggtg gccctttccg tgagacgcca ttgcgcgatt tggcaacaat gacgccggat
    29521 caagcctgcc gtcatccgaa ctggtcgatg gggcgtaaaa tttctgtcga ttcggctacc
    29581 atgatgaaca aaggtctgga atacattgaa gcgcgttggc tgtttaacgc cagcgccagc
    29641 cagatggaag tgctgattca cccgcagtca gtgattcact caatggtgcg ctatcaggac
    29701 ggcagtgttc tggcgcagct gggggaaccg gatatgcgta cgccaattgc ccacaccatg
    29761 gcatggccga atcgcgtgaa ctctggcgtg aagccgctcg atttttgcaa actaagtgcg
    29821 ttgacatttg ccgcaccgga ttatgatcgt tatccatgcc tgaaactggc gatggaggcg
    29881 ttcgaacaag gccaggcagc gacgacagca ttgaatgccg caaacgaaat caccgttgct
    29941 gcttttcttg cgcaacaaat ccgctttacg gatatcgctg cgttgaattt atccgtactg
    30001 gaaaaaatgg atatgcgcga accacaatgt gtggacgatg tgttatctgt tgatgcgaac
    30061 gcgcgtgaag tcgccagaaa agaggtgatg cgtctcgcaa gctgaggata atccggctac
    30121 agagagtcgc gctatttgtt agcgtagggc ttcagtgata tagtctgcgc catctgatcg
    30181 taagtagttg gctttataag gtcaggtatg ccgtggtttt acacggcttt tttttgtata
    30241 ggcttcagta ttcctgagta ccgtaaaccc tgtcagggaa taaaaaacgc gtgatgttgt
    30301 ctgctactca accacttagc gaaaaattgc cagcgcatgg ctgccgtcat gttgcgatca
    30361 ttatggacgg caatggccgc tgggcaaaaa agcaagggaa gattcgtgcc tttgggcata
    30421 aagccggggc aaaatccgtc cgccgggctg tctcttttgc ggccaacaac ggtattgagg
    30481 cgttaacgct gtatgccttt agtagtgaaa actggaaccg accagcgcag gaagtcagtg
    30541 cgttaatgga actgtttgtg tgggcgctcg atagcgaagt aaaaagtctg caccgacata
    30601 acgtgcgtct gcgtattatt ggcgatacca gtcgctttaa ctcgcgtttg caagaacgta
    30661 ttcgtaaatc tgaagcgcta acagccggga ataccggtct gacgctgaat attgcggcga
    30721 actacggtgg acgttgggat atagtccagg gagtcaggca actggctgaa aaggtgcagc
    30781 aaggaaacct gcaaccagat cagatagatg aagagatgct aaaccagcat gtctgtatgc
    30841 atgaactggc ccctgtagat ttagtaatta ggactggggg ggagcatcgc attagtaact
    30901 ttttgctttg gcaaattgcc tatgccgaac tttactttac agatgttctc tggcccgatt
    30961 tcgatgaaca agactttgaa ggggcgttaa atgcctttgc taatcgagag cgtcgtttcg
    31021 gcggcaccga gcccggtgat gaaacagcct gatgggggtc gcttttgctg aagtatcgcc
    31081 tgatatctgc ttttgtgtta atacccgtcg tcatcgcggc gttgtttctg ttgccgccgg
    31141 tggggttcgc cattgtaacg ctggtggtct gcatgctggc agcgtgggaa tggggacagc
    31201 ttagcggttt taccactcgt tcgcagcgag tatggttggc ggtgttatgc gggttattgt
    31261 tggcgctgat gctttttctg ttgccggaat atcaccgaaa tattcatcaa ccgctggttg
    31321 aaatctcact ttgggcttcg ctgggttggt ggattgtcgc gctattgctg gtgctgtttt
    31381 acccaggttc cgcagcaatc tggcgtaact ctaaaacatt gcgccttatt tttggcgtgc
    31441 taaccattgt tcccttcttc tggggcatgc tggcgttacg ggcctggcac tatgacgaga
    31501 atcattacag tggcgcaata tggctgctct atgtcatgat cctggtatgg ggcgctgact
    31561 ccggcgcata tatgtttggc aaattgtttg gtaaacataa gctggcaccg aaggtttctc
    31621 cgggtaaaac ctggcaaggc tttatcggtg gactcgctac tgcagcggta atctcatggg
    31681 gttatggcat gtgggcgaat ctcgacgtcg ctcccgtcac cttactcatt tgctctattg
    31741 tcgcagcgtt agcctcagtg ctcggcgatc tgaccgagag tatgtttaag cgtgaagcag
    31801 gaattaagga cagcggtcat ttaattccag gacacggtgg tattttagat cgtattgata
    31861 gcctgacggc tgcggtaccg gtctttgctt gcttgttgtt actggtattc aggacgcttt
    31921 aacggaaggt aatatgctga gttttctctg ggatttggct tcgttcatcg ttgcactggg
    31981 tgtacttatc accgtgcatg aatttggtca tttctgggtt gcccggcgtt gtggtgttcg
    32041 cgttgagcgt ttctcaatag ggtttggtaa ggcgctctgg cggcgaactg ataagctcgg
    32101 caccgaatat gttatcgccc tgatcccgtt gggcggttat gtcaaaatgc tggatgagcg
    32161 cgcagaaccg gtcgttccgg aactccgcca ccatgccttc aataataaat ctgtcggcca
    32221 acgagcggcg attattgccg caggtccggt tgcaaacttc atttttgcta tctttgccta
    32281 ctggctggtt tttattattg gtgtgcctgg cgtacgtccg gtggttggcg aaatagcagc
    32341 caattcgata gctgcggaag cacaaattgc accaggtacg gaactaaaag ccgtagatgg
    32401 tatcgaaacg cctgattggg atgccgtgcg tttgcagttg gtcgataaaa ttggcgatga
    32461 aagcaccacc attacagtag cgccatttgg cagcgaccaa cggcgggatg taaagctcga
    32521 tttacgtcac tgggcgtttg agcctgataa agaagatccg gtatcttcgc tggggattcg
    32581 tcctcgtggg ccgcaaattg aacctgtact ggaaaatgtg cagccaaact cggcggcaag
    32641 caaggcaggt ttgcaagcag gcgacaggat cgttaaagtc gatggtcagc ccttaacgca
    32701 gtgggtgacc tttgtgatgc ttgtccggga taacccgggt aaatccttag cgttagaaat
    32761 cgaaaggcag gggagtccct tgtctttgac attaatcccg gagagtaaac cgggtaatgg
    32821 taaagcgatt ggttttgtcg gtattgagcc gaaagtcatt cctttgccag atgagtataa
    32881 agttgtacgc cagtatgggc cgttcaacgc catcgtcgaa gccacggaca aaacgtggca
    32941 gctgatgaag ctgacggtca gtatgctggg aaaattgatc accggtgatg tgaaactgaa
    33001 caacctcagt gggccgatct ctatcgccaa gggggctggg atgacagcgg aactcggggt
    33061 tgtttattac ctgccgtttc ttgcgcttat tagcgtgaac ttagggataa ttaacctgtt
    33121 tccgttgccc gtacttgacg gggggcatct gctgttcctt gcgatcgaaa agatcaaggg
    33181 cggaccggta tccgagcggg ttcaagactt ttgttatcgc attggctcga ttctgctggt
    33241 gctgttaatg gggcttgcac ttttcaatga tttctctcgg ttatgagagt tagttaggaa
    33301 gaacgcataa taacgatggc gatgaaaaag ttgctcatag cgtcgctgct gtttagcagc
    33361 gccaccgtat acggtgctga agggttcgta gtgaaagata ttcatttcga aggccttcag
    33421 cgtgtcgccg ttggtgcggc cctcctcagt atgccggtgc gcacaggcga cacggttaat
    33481 gatgaagata tcagtaatac cattcgcgct ctgtttgcta ccggcaactt tgaggatgtt
    33541 cgcgtccttc gtgatggtga tacccttctg gttcaggtaa aagaacgtcc gaccattgcc
    33601 agcattactt tctccggtaa caaatcggtg aaagatgaca tgctgaagca aaacctcgag
    33661 gcttctggtg tgcgtgtggg cgaatccctc gatcgcacca ccattgccga tatcgagaaa
    33721 ggtctggaag acttctacta cagcgtcggt aaatatagcg ccagcgtaaa agctgtcgtg
    33781 accccgctgc cgcgcaaccg tgttgaccta aaactggtgt tccaggaagg tgtgtcagct
    33841 gaaatccagc aaattaacat tgttggtaac catgctttca ccaccgacga actgatctct
    33901 catttccaac tgcgtgacga agtgccgtgg tggaacgtgg taggcgatcg taaataccag
    33961 aaacagaaac tggcgggcga ccttgaaacc ctgcgcagct actatctgga tcgcggttat
    34021 gcccgtttca acatcgactc tacccaggtc agtctgacgc cagataaaaa aggtatttac
    34081 gtcacggtga acatcaccga aggcgatcag tacaagcttt ctggcgttga agtgagcggc
    34141 aaccttgccg ggcactccgc tgaaattgag cagctgacta agatcgagcc gggtgagctg
    34201 tataacggca ccaaagtgac caagatggaa gatgacatca aaaagcttct cggtcgctat
    34261 ggttatgcct atccgcgcgt acagtcgatg cccgaaatta acgatgccga caaaaccgtt
    34321 aaattacgtg tgaacgttga tgcgggtaac cgtttctacg tgcgtaagat ccgttttgaa
    34381 ggtaacgata cctcgaaaga tgccgtcctg cgtcgcgaaa tgcgtcagat ggaaggtgca
    34441 tggctgggga gcgatctggt cgatcagggt aaggagcgtc tgaatcgtct gggcttcttt
    34501 gaaactgtcg ataccgatac ccaacgtgtt ccgggtagcc cggaccaggt tgatgtcgtc
    34561 tacaaggtaa aagagcgcaa caccggtagc ttcaactttg gtattggtta cggtactgaa
    34621 agtggcgtga gcttccaggc tggtgtgcag caggataact ggttaggtac aggttatgct
    34681 gttggtatca acgggaccaa aaacgattac cagacctatg ctgaactgtc ggtaaccaac
    34741 ccgtacttca ccgtagatgg cgtaagcctc ggtggtcgtc tcttctataa tgacttccag
    34801 gcagatgacg ccgacctgtc cgactatacc aacaagagtt atggtacaga cgtgacgttg
    34861 ggcttcccga ttaacgaata taactcgctg cgtgcaggtc tgggttatgt acataactcc
    34921 ctgtccaaca tgcagcctca ggttgcgatg tggcgttatc tgtactctat gggtgaacat
    34981 ccgagcacct ctgatcagga taacagcttc aaaacggacg acttcacgtt caactatggt
    35041 tggacctata acaagcttga ccgtggttac ttcccgacag atggttcacg tgtcaacctg
    35101 accggtaaag tgaccattcc tggatcggat aacgaatact acaaagtgac gttagacacg
    35161 gcgacttatg tgccgatcga tgacgatcac aaatgggttg ttctggggcg tacccgctgg
    35221 ggttatggtg atggtttagg cggcaaagag atgccgttct acgagaactt ctatgccggt
    35281 ggttccagca ccgtgcgtgg cttccagtcc aataccattg gtccgaaagc agtttacttc
    35341 ccgcatcagg ccagtaatta tgatccggac tatgattacg aatgtgcgac tcaggacggc
    35401 gcgaaagacc tgtgtaaatc ggatgatgct gtaggcggta acgccatggc ggttgccagc
    35461 ctcgagttca tcaccccgac gccgtttatt agcgataagt atgctaactc ggttcgtact
    35521 tccttcttct gggatatggg taccgtttgg gatacaaact gggattccag ccaatattct
    35581 ggatatccgg actatagtga tccaagcaat atccgtatgt ctgcgggtat cgcattacaa
    35641 tggatgtccc cattggggcc gttggtgttc tcctacgccc agccgttcaa aaagtacgat
    35701 ggagacaagg cagaacagtt ccagtttaac atcggtaaaa cctggtaagt gttctccaca
    35761 aaggaatgta gtggtagtgt agcgatgact ttaggcgatc aatataagat cgccgggcca
    35821 cgcaaagaac tgcaccctcc ggtgcaaatg ggatggtaag gagtttattg tgaaaaagtg
    35881 gttattagct gcaggtctcg gtttagcact ggcaacttct gctcaggcgg ctgacaaaat
    35941 tgcaatcgtc aacatgggca gcctgttcca gcaggtagcg cagaaaaccg gtgtttctaa
    36001 cacgctggaa aatgagttca aaggccgtgc cagcgaactg cagcgtatgg aaaccgatct
    36061 gcaggctaaa atgaaaaagc tgcagtccat gaaagcgggc agcgatcgca ctaagctgga
    36121 aaaagacgtg atggctcagc gccagacttt tgctcagaaa gcgcaggctt ttgagcagga
    36181 tcgcgcacgt cgttccaacg aagaacgcgg caaactggtt actcgtatcc agactgctgt
    36241 gaaatccgtt gccaacagcc aggatatcga tctggttgtt gatgcaaacg ccgttgctta
    36301 caacagcagc gatgtaaaag acatcactgc cgacgtactg aaacaggtta aataagtaat
    36361 gccttcaatt cgactggctg atttagcgca gcagttggat gcagaactac acggtgatgg
    36421 cgatatcgtc atcaccggcg ttgcgtccat gcaatctgca caaacaggtc acattacgtt
    36481 catggttaac ccaaaatacc gtgagcattt aggcttgtgc caggcgtccg cggttgtcat
    36541 gacccaggac gatcttcctt tcgcgaaaag tgccgcactg gtagtgaaga atccctacct
    36601 gacttacgcg cgcatggcgc aaattttaga taccacgccg cagcccgcgc agaacattgc
    36661 acccagtgcg gtgatcgacg cgacggcgaa gctgggtaac aacgtatcga ttggcgctaa
    36721 cgcggtgatt gagtccggcg ttgaactggg cgataacgtg attatcggtg ccggttgctt
    36781 cgtaggtaaa aacagcaaaa tcggtgcagg ttcgcgtctc tgggcgaacg taaccattta
    36841 ccatgagatc cagatcggtc agaattgcct gatccagtcc ggaacagtgg taggcgcaga
    36901 cggctttggt tatgccaacg atcgtggtaa ctgggtgaag atcccacaga ttggtcgcgt
    36961 aattattggc gatcgcgtgg agatcggtgc ctgcacaacc atcgatcgcg gcgcgctgga
    37021 tgacactatt attggcaatg gcgtgatcat tgataaccag tgccagattg cacataacgt
    37081 cgtgattggc gacaatacgg cggttgccgg tggcgtcatt atggcgggca gcctgaaaat
    37141 tggtcgttac tgcatgatcg gcggagccag cgtaatcaac gggcatatgg aaatatgcga
    37201 caaagtgacg gttacgggca tgggtatggt gatgcgtccc atcactgaac caggcgtcta
    37261 ttcctcaggc attccgctgc aacccaacaa agtctggcgc aaaaccgctg cactggtgat
    37321 gaacattgat gacatgagca agcgtctgaa atcgcttgag cgcaaggtta atcaacaaga
    37381 ctaacgttcc atcttttgtt cgccaaactt tacggcctgt ctcattctta cgattgcggc
    37441 aggccgtgtt attattgtcg tttcttatat tttgacagga agagtatctt gactactaac
    37501 actcatactc tgcagattga agagatttta gaacttctgc cgcaccgttt cccgttctta
    37561 ctggtggatc gcgtgctgga ttttgaagaa ggtcgttttc tgcgcgcagt aaaaaatgtc
    37621 tctgtcaatg agccattctt ccagggccat ttccctggaa aaccgatttt cccgggtgtg
    37681 ctgattctgg aagcaatggc acaggcaaca ggtattctgg cgtttaaaag cgtaggaaaa
    37741 ctggaaccgg gtgagctgta ctacttcgct ggtattgacg aagcgcgctt caagcgcccg
    37801 gtcgtgcctg gcgatcaaat gatcatggaa gtcactttcg aaaaaacgcg ccgcggcctg
    37861 acccgtttta aaggggttgc tctggtcgat ggtaaagtag tttgcgaagc aacgatgatg
    37921 tgtgctcgta gccgggaggc ctgatacgtg attgataaat ccgcctttgt gcatccaacc
    37981 gccattgtgg aagagggcgc gtcaattggc gcgaacgcac acattggtcc tttttgtatc
    38041 gttggacccc atgtcgaaat tggtgagggt accgtactga aatctcacgt tgtcgtgaat
    38101 ggtcatacta aaattggccg cgataatgag atttatcagt tcgcctccat cggcgaagtt
    38161 aaccaggatc tgaaatatgc tggcgaaccg acccgtgtgg aaatcggcga tcgtaaccgc
    38221 attcgcgaaa gcgtcaccat tcatcgtggc acagtccagg gcggtggatt gacgaaggtg
    38281 ggcagcgaca acttactgat gatcaacgcg cacattgcgc acgattgtac ggtaggtaac
    38341 cgctgtattc tcgccaacaa cgcaacgctg gcgggtcacg tatcggttga cgacttcgcg
    38401 atcatcggcg gcatgaccgc agtccatcag ttctgcatca ttggtgcgca cgtgatggtt
    38461 ggcggctgct ccggtgtggc gcaggacgtc cctccttatg tcattgcgca gggtaaccac
    38521 gcaacgccgt tcggtgtcaa tatcgaaggg ctgaagcgcc gcggattcag ccgtgaggcg
    38581 attaccgcta tccgcaatgc gtataagctg atttatcgta gcggtaaaac gctcgatgaa
    38641 gtgaaaccgg aaattgctga actggcggaa acatatccgg aagtgaaagc ctttaccgat
    38701 ttctttgcac gctcaacgcg cggtctgatt cgttaatgac tgaacagcgt ccattaacga
    38761 ttgccctggt cgccggagaa acctccggcg atatcctggg ggccggttta atccgcgctc
    38821 tgaaagaaca tgtgcccaac gcccgctttg ttggtgttgc cgggccacga atgcaggctg
    38881 aaggctgcga agcctggtac gaaatggaag aactggcggt gatgggcatt gttgaagtgc
    38941 tcggtcgtct gcgtcgctta ctgcatattc gtgccgatct gacaaagcgt tttggcgaac
    39001 tgaagccaga tgtttttgtt ggtattgatg cgcctgactt caatattact cttgaaggta
    39061 acctcaaaaa gcagggtatc aaaaccattc attacgtcag tccgtcagtc tgggcgtggc
    39121 gacagaaacg tgttttcaaa ataggcagag ccaccgatct ggtgctcgca tttctgcctt
    39181 tcgaaaaagc gttttatgac aaatacaacg taccgtgccg ctttatcggt cataccatgg
    39241 ctgatgccat gccattagat ccagataaaa atgccgcccg tgatgtgctg gggatccctc
    39301 acgatgccca ctgcctggcg ttgctaccgg ggagccgtgg tgcagaagtt gaaatgctta
    39361 gtgccgattt cctgaaaacg gcccagcttt tgcgccagac atatccggat ctcgaaatcg
    39421 tggtgccact ggtgaatgcc aaacgccgcg agcagtttga acgcatcaaa gctgaagtcg
    39481 cgccagacct ttcagttcat ttgctggatg ggatgggccg tgaggcgatg gtcgccagcg
    39541 atgcggcgct actggcgtcg ggtacggcag ccctggagtg tatgctggcg aaatgcccga
    39601 tggtggtggg atatcgcatg aagcctttta ccttctggtt ggcgaagcgg ctggtgaaaa
    39661 ctgattatgt ctcgctgcca aatctgctgg cgggcagaga gttagtcaaa gaattattgc
    39721 aggaagagtg tgagccgcaa aaactggctg cggcgctgtt accgctgttg gcgaacggga
    39781 aaaccagcca cgcgatgcac gataccttcc gtgaactgca tcagcagatc cgctgcaatg
    39841 ccgatgagca ggcggcacaa gccgttctgg agttagcaca atgatcgaat ttgtttatcc
    39901 gcacacgcag ctggttgcgg gtgtggatga agtcggacgc gggccgttag ttggcgcggt
    39961 cgtcaccgct gcggtgatcc ttgacccggc gcgcccgatt gccgggctga atgattccaa
    40021 aaagctgagc gaaaaacgcc gtctggcgct ctatgaagag atcaaagaga aagcgttgag
    40081 ctggagtctg ggccgcgcgg aaccccacga aatcgacgag ctgaacattc ttcatgcgac
    40141 catgctggcg atgcagcgtg ccgtcgctgg gctgcatatt gcgccggaat atgtgttgat
    40201 tgatggtaac cgctgcccga aattaccgat gcctgcgatg gctgtggtga aaggcgatag
    40261 ccgcgtaccg gaaatcagtg ccgcgtctat cctggcgaaa gtgacgcgtg acgccgaaat
    40321 ggcggtgctg gatattgttt tcccgcaata tggttttgcc caacacaaag ggtacccaac
    40381 cgcttttcat ctggaaaaac tggctgaaca cggcgcgacc gaacaccatc ggcgcagctt
    40441 tgggcctgtc aaacgcgcac tgggacttgc gtcctgattc ttgtgtcgag attaagtaaa
    40501 ccggaatctg aagatgtctg aaccacgttt cgtacacctg cgggtgcaca gcgactactc
    40561 gatgatcgat ggcctggcca aaaccgcacc gttggtaaaa aaggcggcgg cgttgggtat
    40621 gccagcactg gcgatcaccg atttcaccaa cctttgtggt ctggtgaagt tctacggagc
    40681 gggacatggc gcagggatta agcctatcgt cggggcagat tttaacgtcc agtgcgacct
    40741 gctgggtgat gagttaaccc acctgacggt actggcggcg aacaataccg gctatcagaa
    40801 tctgacgttg ctgatctcaa aagcgtatca gcgcgggtac ggtgccgccg ggccgatcat
    40861 cgatcgcgac tggcttatcg aattaaacga agggttgatc cttctttccg gcggacgcat
    40921 gggcgacgtc ggacgcagtc ttttgcgtgg taacagcgcg ctggtagatg agtgtgtcgc
    40981 gttttatgaa gaacacttcc cggatcgcta ttttctcgag ctgatccgca ccggcaggcc
    41041 ggatgaagaa agctatctgc acgcggcggt ggaactggcg gaagcgcgcg gtttgcccgt
    41101 cgtggcgacc aacgacgtgc gctttatcga cagcagcgac tttgacgcac acgaaatccg
    41161 cgtcgcgatc cacgacggct ttaccctcga cgatcctaaa cgcccgcgta actattcgcc
    41221 gcagcaatat atgcgtagcg aagaggagat gtgtgagctg tttgccgaca tccccgaagc
    41281 ccttgccaac accgttgaga tcgccaaacg ctgtaacgta accgtgcgtc ttggtgaata
    41341 cttcctgccg cagttcccga ccggggacat gagcaccgaa gattatctgg tcaagcgtgc
    41401 aaaagagggc ctggaagagc gtctggcctt tttattccct gatgaggaag aacatcttaa
    41461 gcgccgcccg gaatatgacg aacgtctgga gactgaactt caggttatca accagatggg
    41521 cttcccgggc tacttcctca tcgttatgga atttatccag tggtcgaaag ataacggcgt
    41581 accggtaggg ccaggccgtg gctccggtgc gggttcactg gtggcctacg cgctgaaaat
    41641 caccgacctc gatccgctgg aatttgacct gctgttcgaa cgtttcctta acccggaacg
    41701 tgtctccatg cctgacttcg acgttgactt ctgtatggag aaacgcgatc aggttatcga
    41761 gcacgtagcg gacatgtacg gtcgtgatgc ggtatcgcag atcatcacct tcggtacaat
    41821 ggcggcgaaa gcggtgatcc gcgacgtagg ccgcgtgctg gggcatccgt acggctttgt
    41881 cgatcgtatc tcgaaactga tcccgcccga tccggggatg acgctggcga aagcgtttga
    41941 agccgagccg cagctgccgg aaatctacga agcggatgaa gaagttaagg cgctgatcga
    42001 catggcgcgc aaactggaag gggtcacccg taacgccggt aagcacgccg gtggggtggt
    42061 tatcgcgccg accaaaatta ccgattttgc gccgctttac tgcgatgaag agggcaaaca
    42121 tccggtcacc cagtttgata aaagcgacgt tgaatacgcc ggactggtga agttcgactt
    42181 ccttggtttg cgtacgctca ccatcatcaa ctgggcgctg gagatgatca acaagcggcg
    42241 ggcgaagaat ggcgagccgc cgctggatat cgctgcgatc ccgctggatg ataagaaaag
    42301 cttcgacatg ctgcaacgct cggaaaccac ggcggtattc cagcttgaat cgcgcggcat
    42361 gaaggacctg atcaagcgtc tacaacctga ctgcttcgaa gatatgatcg ccctagtggc
    42421 actgttccgc cccggtccgt tgcaatcagg gatggtggat aactttatcg accgtaaaca
    42481 tggtcgtgaa gagatctcct atccggacgt acagtggcag catgaaagcc tgaaaccggt
    42541 actggagcca acctacggca ttatcctgta tcaggaacag gtcatgcaga ttgcgcaggt
    42601 gctttctggt tataccctcg gtggcgcgga tatgctgcgt cgtgcgatgg gtaagaaaaa
    42661 gccggaagag atggctaagc aacgttctgt atttgctgaa ggtgcagaaa agaacggaat
    42721 caacgctgaa ctggcgatga aaatcttcga cctggtggag aaattcgctg gttacggatt
    42781 taacaaatcg cactctgcgg cctatgcttt ggtgtcatat caaacgttat ggctgaaagc
    42841 gcactatcct gcggagttta tggcggcggt aatgaccgcc gatatggaca acaccgagaa
    42901 ggtggtgggt ctggtggatg agtgctggcg gatggggctg aaaatcctgc caccagatat
    42961 aaactccggt ctttaccatt tccacgtcaa cgacgacggc gaaatcgtgt atggtattgg
    43021 cgcgatcaaa ggggtcggtg aaggtccgat tgaggccatc atcgaagccc gtaataaagg
    43081 cggctacttc cgcgaactgt ttgatctctg cgcccgtacc gacaccaaaa agttgaaccg
    43141 tcgcgtgctg gaaaaactga tcatgtccgg ggcgtttgac cgtcttgggc cacatcgcgc
    43201 agcgctgatg aactcgctgg gcgatgcgtt aaaagcggca gatcaacacg cgaaagcgga
    43261 agctatcggt caggccgata tgttcggcgt gctggccgaa gagccggaac aaattgaaca
    43321 atcctacgcc agctgccaac cgtggccgga gcaggtggta ttagatgggg aacgtgaaac
    43381 gttaggcctg tacctgaccg gacaccctat caaccagtat ttaaaagaga ttgagcgtta
    43441 tgtcggaggc gtaaggctga aagacatgca cccgacagaa cgtggtaaag tcatcacggc
    43501 tgcggggctc gttgttgccg cgcgggttat ggtcaccaag cgcggcaatc gtatcggtat
    43561 ctgcacgctg gatgaccgtt ccgggcggct ggaagtgatg ttgtttactg acgccctgga
    43621 taaataccag caattgctgg aaaaagaccg catacttatc gtcagcggac aggtcagctt
    43681 tgatgacttc agcggtgggc ttaaaatgac cgctcgcgaa gtgatggata ttgacgaagc
    43741 ccgggaaaaa tatgctcgcg ggcttgctat ctcgctgacg gacaggcaaa ttgatgacca
    43801 gcttttaaac cgactccgtc agtctctgga accccaccgc tctgggacaa ttccagtaca
    43861 tctctactat cagagggcgg atgcacgcgc gcggttgcgt tttggcgcga cgtggcgtgt
    43921 ctctccgagc gatcgtttat taaacgatct ccgtggcctc attggttcgg agcaggtgga
    43981 actggagttt gactaataca ggaatactat gagtctgaat ttccttgatt ttgaacagcc
    44041 gattgcagag ctggaagcga aaatcgattc tctgactgcg gttagccgtc aggatgagaa
    44101 actggatatt aacatcgatg aagaagtgca tcgtctgcgt gaaaaaagcg tagaactgac
    44161 acgtaaaatc ttcgccgatc tcggtgcatg gcagattgcg caactggcac gccatccaca
    44221 gcgtccttat accctggatt acgttcgcct ggcatttgat gaatttgacg aactggctgg
    44281 cgaccgcgcg tatgcagacg ataaagctat cgtcggtggt atcgcccgtc tcgatggtcg
    44341 tccggtgatg atcattggtc atcaaaaagg tcgtgaaacc aaagaaaaaa ttcgccgtaa
    44401 ctttggtatg ccagcgccag aaggttaccg caaagcactg cgtctgatgc aaatggctga
    44461 acgctttaag atgcctatca tcacctttat cgacaccccg ggggcttatc ctggcgtggg
    44521 cgcagaagag cgtggtcagt ctgaagccat tgcacgcaac ctgcgtgaaa tgtctcgcct
    44581 cggcgtaccg gtagtttgta cggttatcgg tgaaggtggt tctggcggtg cgctggcgat
    44641 tggcgtgggc gataaagtga atatgctgca atacagcacc tattccgtta tctcgccgga
    44701 aggttgtgcg tccattctgt ggaagagcgc cgacaaagcg ccgctggcgg ctgaagcgat
    44761 gggtatcatt gctccgcgtc tgaaagaact gaaactgatc gactccatca tcccggaacc
    44821 actgggtggt gctcaccgta acccggaagc gatggcggca tcgttgaaag cgcaactgct
    44881 ggcggatctg gccgatctcg acgtgttaag cactgaagat ttaaaaaatc gtcgttatca
    44941 gcgcctgatg agctacggtt acgcgtaatt cgcaaaagtt ctgaaaaagg gtcacttcgg
    45001 tggccctttt ttatcgccac ggtttgagca ggctatgatt aaggaaggat tttccaggag
    45061 gaacacatga acatcattgc cattatggga ccgcatggcg tcttttataa agatgagccc
    45121 atcaaagaac tggagtcggc gctggtggcg caaggctttc agattatctg gccacaaaac
    45181 agcgttgatt tgctgaaatt tatcgaacat aaccctcgaa tttgcggcgt gatttttgac
    45241 tgggatgagt acagtctcga tttatgtagc gatatcaatc agcttaatga atatctcccg
    45301 ctttatgcct tcatcaacac ccactcgacg atggatgtca gcgtgcagga tatgcggatg
    45361 gcgctctggt tttttgaata tgcgctgggg caggcggaag atatcgccat tcgtatgcgt
    45421 cagtacaccg acgaatatct tgataacatt acaccgccgt tcacgaaagc cttgtttacc
    45481 tacgtcaaag agcggaagta caccttttgt acgccggggc atatgggcgg caccgcatat
    45541 caaaaaagcc cggttggctg tctgttttat gattttttcg gcgggaatac tcttaaggct
    45601 gatgtctcta tttcggtcac cgagcttggt tcgttgctcg accacaccgg gccacacctg
    45661 gaagcggaag agtacatcgc gcggactttt ggcgcggaac agagttatat cgttaccaac
    45721 ggaacatcga cgtcgaacaa aattgtgggt atgtacgccg cgccatccgg cagtacgctg
    45781 ttgatcgacc gcaattgtca taaatcgctg gcgcatctgt tgatgatgaa cgatgtagtg
    45841 ccagtctggc tgaaaccgac gcgtaatgcg ttggggattc ttggtgggat cccgcgccgt
    45901 gaatttactc gcgacagcat cgaagagaaa gtcgctgcta ccacgcaagc acaatggccg
    45961 gttcatgcgg tgatcaccaa ctccacctat gatggcttgc tctacaacac cgactggatc
    46021 aaacagacgc tggatgtccc gtcgattcac ttcgattctg cctgggtgcc gtacacccat
    46081 tttcatccga tctaccaggg taaaagtggt atgagcggcg agcgtgttgc gggaaaagtg
    46141 atcttcgaaa cgcaatcgac ccacaaaatg ctggcggcgt tatcgcaggc ttcgctgatc
    46201 cacattaaag gcgagtatga cgaagaggcc tttaacgaag cctttatgat gcataccacc
    46261 acctcgccca gttatcccat tgttgcttcg gttgagacgg cggcggcgat gctgcgtggt
    46321 aatccgggca aacggctgat taaccgttca gtagaacgag ctctgcattt tcgcaaagag
    46381 gtccagcggc tgcgggaaga gtctgacggt tggtttttcg atatctggca accgccgcag
    46441 gtggatgaag ccgaatgctg gcccgttgcg cctggcgaac agtggcacgg ctttaacgat
    46501 gcggatgccg atcatatgtt tctcgatccg gttaaagtca ctattttgac accggggatg
    46561 gacgagcagg gcaatatgag cgaggagggg atcccggcgg cgctggtagc aaaattcctc
    46621 gacgaacgtg ggatcgtagt agagaaaacc ggcccttata acctgctgtt tctctttagt
    46681 attggcatcg ataaaaccaa agcaatggga ttattgcgtg ggttgacgga attcaaacgc
    46741 tcttacgatc tcaacctgcg gatcaaaaat atgctacccg atctctatgc agaagatccc
    46801 gatttctacc gcaatatgcg tattcaggat ctggcacaag ggatccataa gctgattcgt
    46861 aaacacgatc ttcccggttt gatgttgcgg gcattcgata ctttgccgga gatgatcatg
    46921 acgccacatc aggcatggca acgacaaatt aaaggcgaag tagaaaccat tgcgctggaa
    46981 caactggtcg gtagagtatc ggcaaatatg atcctgcctt atccaccggg cgtaccgctg
    47041 ttgatgcctg gagaaatgct gaccaaagag agccgcacag tactcgattt tctactgatg
    47101 ctttgttccg tcgggcaaca ttaccccggt tttgaaacgg atattcacgg cgcgaaacag
    47161 gacgaagacg gcgtttaccg cgtacgagtc ctaaaaatgg cgggataact tgccagagcg
    47221 gcttccgggc gagtaacgtg ctgttaacaa ataaaggaga cgttatgctg ggtttaaaac
    47281 aggttcacca tattgcgatt attgcgacgg attatgcggt gagcaaagct ttctactgcg
    47341 atattcttgg tttcacgctg caaagcgaag tctatcgcga agcgcgcgac tcatggaaag
    47401 gggatttggc gcttaatggg caatatgtga ttgagctttt ctcatttccg ttcccgccgg
    47461 aacgacccag ccgaccggaa gcttgcggtc tgcgtcatct ggcttttagc gttgatgaca
    47521 tcgatgcggc agtggcgcac cttgaaagcc ataacgtgaa gtgtgaaacc atccgtgtcg
    47581 atccatacac gcaaaaacgc ttcaccttct ttaacgatcc ggacgggctg ccgttggaac
    47641 tgtatgagca gtaaggcttg tcatcgccgc atttgcccgg taacgtgccg ggcattgcta
    47701 ctgtaaaatc gcaccatcat gacactcacg ctcaatagac aacttctcac ctcacgccag
    47761 attctggtgg cctttagcgg cgggcttgac tccaccgttc tgctgcatca gttggtgcag
    47821 tggcggacgg aaaatccggg tgtcgctctg cgcgctattc atgtgcatca cggtttaagt
    47881 gccaatgccg atgcctgggt tacgcattgc gaaaacgtct gccaacagtg gcaggtgccg
    47941 ctggtggtcg aacgcgtaca acttgcgcaa gaaggactgg gcattgaggc ccaggcgcgg
    48001 caggcacgtt atcaggcatt tgcccgcacc ttgttgcccg gtgaagtgct ggtcaccgcg
    48061 caacatctcg acgatcaatg tgaaaccttt ctgctggcgc taaaacgcgg cagtggccct
    48121 gccgggcttt cggctatggc ggaagtctcg gagtttgccg gaacgcggct tattcgcccg
    48181 ttgctcgccc gcacgcgggg ggaactggtg cagtgggcgc gtcagtatga tttacgctgg
    48241 attgaagacg aaagtaatca ggacgactca tacgatcgta actttctgcg cctgcgcgta
    48301 gtgccgttat tgcagcagcg ttggccgcat tttgccgaag caacggcccg cagcgccgca
    48361 ctttgtgctg aacaagagag cctgctggat gaactgctgg cagatgattt agcacactgt
    48421 caatcgccgc aggggacgct gcagattgtg ccaatgctgg cgatgagtga tgcccgccgc
    48481 gcggcgatta tccgccgctg gctggcaggg cagaatgcac cgatgccttc ccgcgacgcg
    48541 ttggtgagga tctggcagga agtggcgctg gcgcgggaag atgcctcacc ctgtttacgt
    48601 ttgggcgcgt ttgaaatccg acgctatcag tcgcaactgt ggtggattaa atccgtcacc
    48661 gggcaaagcg aaaacattgt gccgtggcag acgtggcttc aaccgctgga attaccggcg
    48721 gggctgggaa gtgtacagct taatgcggga ggcgatattc gccctccgcg tgcagacgaa
    48781 gcggtcagcg tgcgtttcaa agcgccagga ttgctgcata ttgtcgggcg taacggcgga
    48841 cgtaagctaa agaaaatctg gcaagagctg ggcgtgccgc cgtggctacg tgacaccacg
    48901 ccactgctgt tttatggcga aacgctgatt gcggcggcag gggtatttgt gacgcaagaa
    48961 ggtgtggctg aaggtgagaa tggcgtaagt tttgtctggc agaaaacgct tagttaagtg
    49021 aaagccggat aagacgcatc aaacgtcgca tccggcgaaa gtcaatcagg attcgcttac
    49081 caccaccgta ccgatttccg ggtggctaaa gctggtaatt ttatccagac gcagctcgcg
    49141 ggtttcgcca gcggcctcga cgaccaggta ctccacattt ttgcgggaga ctaaatcact
    49201 ggcttttgcc tgcaattttt cgccatcttt cagctcaagt gtcagcatta aatgatgctg
    49261 gcaggcgagc tcaagattat cgtaatcatc acaattgatt ggttgatacg tatcattcat
    49321 tgacataatc gctcaccagt aagtttgccg cagcgtatgc tgctttttcc ctgacagcct
    49381 cagaaagggc gtcgtcggca gccatttcat tcagcacttt caaaacgcag cccagcgcgt
    49441 ccggaacgta tcctaagtct ccgctggcga tttccgcgta ccgcttgcgt attaactcac
    49501 aatatttttc cacatgccct cctgtcagca ctctgactta accgtggatg caagtctaag
    49561 cctacgaaga taaactctgt ttcgcaaggt gactatacca cactcatttc tgcaatatca
    49621 gcgccgcaac tgcacgtatt ccgttacaat ggcctcctga ttcgaaagga gttttcttat
    49681 ggcgcttaaa gcgacaattt ataaagcgac ggttaatgtg gccgatctcg accgcaacca
    49741 gtttctcgat gcctctctga cgctggcgcg ccatccttca gaaacccagg agcgtatgat
    49801 gctgcgcttg ctggcgtggc tgaaatatgc tgatgaacgt ctgcaattta cccgtggttt
    49861 gtgtgccgat gatgagccgg aagcgtggct gcgtaacgat cacctgggca ttgatttgtg
    49921 gattgagctg gggctgccgg atgagcggcg gattaagaaa gcctgcaccc aggccgcaga
    49981 agtggcgctg tttacctata atagtcgggc ggcgcaaatc tggtggcagc aaaatcagag
    50041 caaatgtgtg cagtttgcca atctttccgt ctggtatctg gacgatgaac aactggcgaa
    50101 agtaagcgcc tttgccgatc gtaccatgac gctgcaggca acgattcagg atggcgtgat
    50161 ctggttatcg gatgataaga ataatctgga agtgaactta accgcctggc aacaaccttc
    50221 atgattgtga tttcccgaca tgttgctatt cccgatggtg agcttgagat caccgccatt
    50281 cgtgcgcagg gcgcgggcgg gcagcatgtt aataagacct caacggctat tcatctgcgt
    50341 tttgacattc gggcgtcccg cctgccagag tattacaaag agcgtctgct cgccgccagc
    50401 catcatttga tcagcagtga tggcgtgatt gtcattaagg cacaggaata ccgcagtcag
    50461 gaactgaacc gcgaagcagc tctggcccgg ctggtggcta tgattaaaga attaacaaca
    50521 gaaaaaaaag cccgacgacc cacgcggccc acccgtgcat cgaaagagcg caggctggca
    50581 tcgaaagcac aaaaatcaag cgtgaaggcg atgcgcggca aagtgcgcag cggtcgggaa
    50641 taaaaagaag gaatggatgg tgaaaaaagc gatagtgaca gcgatggctg taatcagcct
    50701 ctttactctg atgggatgta ataatcgggc cgaagtcgat acgctttctc cggcgcaggc
    50761 tgccgaactg aaaccgatgc cgcaaagttg gcgcggcgtg ctgccgtgtg ccgattgcga
    50821 aggaatcgaa acctctctgt tcctcgaaaa agacggaaca tgggtgatga atgagcgtta
    50881 tctcggtgct cgtgaagaac cttcctcctt cgcttcctac ggtacatggg cgcgaaccgc
    50941 tgacaagctg gtattaaccg acagcaaagg tgaaaagtca tattatcggg cgaaaggcga
    51001 tgcgctggag atgctcgatc gtgaaggcaa tccgattgaa tcgcagttca actatacgct
    51061 ggaagcggca caatccagtt tacctatgac gccgatgacc ctgcggggca tgtattttta
    51121 tatggctgat gcggcgacct tcactgattg cgcgaccgga aaacgtttca tggtagcgaa
    51181 taacgcagag ctggagcgta gctacctggc tgcgcgcggt cacagtgaaa aaccggtgtt
    51241 actgtcagta gaaggtcact ttacgcttga gggtaatccg gataccggtg cgccgactaa
    51301 agtattggca cccgatacgg cagggaaatt ttaccccaac caggattgca gtagtttggg
    51361 gcagtaaccc gtcttgagac agaaacaaac gcaaaacagg ccagaaggat atatttcaac
    51421 attttgaatt tgcacgtttt ttgtaggccg gataaggcgt ttacgccgca tccggcaatg
    51481 gtgctcaacg cctgatgcga cgctggcgcg tcttatcatg cctacaaccc ccctcatacc
    51541 ttaaggcgga taaggcattt actttatcac cgggtcaaac caacaaagcg acccgccttg
    51601 atataaatcc caggcttcag gtgcccaaca tactgtaact gcgtttctgg cttaaacgca
    51661 gagacatcac caatacgcat atgcatcaga tcggcagggc taatccagcc cgattgcgcc
    51721 agtgtaagtg gatgcccggc tttggcaaag gcatccgtga caaattccga acaaaaccac
    51781 gactttttgt ctccttcgcc cacactgctt aactgcgctt tcgccaggcc gctgacgcac
    51841 tgttggcgaa aatcctcgga gaacggattc agtgagcaca tctggcgagt caccataaag
    51901 ggaataaatt cgacaatgcc gcgatagtta taaccgctat ctttgatttt attggcaaac
    51961 gcggtgatat ctgtggcttg ttgcggggta agatccggga ctcgtaagac gaaaagctta
    52021 tcactatgct tcatcgcttt tttaagggaa acgatctgga cgccagcgcc tgtcgcttct
    52081 gcaacgttat tatcacccag aaagattgca acgtgactca cagaggaagt gctgaagacg
    52141 cggattccaa atgaggttac cccaaggctt gaggagaaca gcaaatcgcc gggtttgaga
    52201 tcaggtgccg ttatttcttt tattgattgt tcggtgaaag agctttgatg ctggaatttg
    52261 acagcccatg tttttgcctc ggcatctact gctgtggctg atgggtctgg ctggctgata
    52321 tcaacggtac aagccgaaag taaaagaaag ctggggagaa acaggcggca gtacgccttt
    52381 ggtttatcca ttttatacaa tccatgtaaa aaaagggccc tgaaattcag gaccctttct
    52441 ggcatcagcc tttaatctgt ttcaccagat attcgacgat gtcaccagtc ttaattaact
    52501 gtttctcgcc gttgcgacga tatttatatt cgatatcgtc gttgtcgagg ttacggtcgc
    52561 ccagcacaat agtgtgcgga ataccgatca gttccatatc agcaaacatc acgcccggac
    52621 gctctttgcg gtcatccagc agcacttcga taccttgtgc acgcagttcg ctgtacagtt
    52681 tctcagcaag ctcttgtacg cggaaggatt tgtgcatgtt catcggcaga atcgccacct
    52741 ggaacggcgc gatagcgtca ggccatacga tgcctcgttc gtcgtagttc tgctcaatcg
    52801 ccgcagctac cacacgcgtt accccgatac cgtagcaacc catcgtcagg atttggttac
    52861 ggccatcttc accctgtacg gaggctttca gtgcttcgga gtacttggta cccagctgga
    52921 agatgtgacc aacttcgata ccacgtttga tcagcagcgt accctggcca tccgggcttg
    52981 gatcgccagc caccacgtta cggatatctg caacttccgg ggtagcgaca tcgcgatccc
    53041 agttgatgcc gaagtagtgt ttaccatcga tgttagcacc agcagcgaaa tcactcatcg
    53101 ccgcaacggt acggtcaatc accaccggaa tcggcatgtt taccggaccc agtgaacccg
    53161 gaccggcttt aaccacggca cgaatttctt cttcggtcgc gaaagtcagc gggcttgcaa
    53221 cctgcggcag tttttctgct ttaacttcgt tcagctcgtg atcaccgcgc accagcagcg
    53281 caaccagcgg gaagctgctg ccttcaaccg ctttaaccag cagagtctta accgttttct
    53341 caatcggcag attgaactgt tcaaccagtt ccgcgatggt tttcgcgttc ggcgtatcaa
    53401 ccagcgtcat ttcctgggta gcagcagcgc gcggttcttt cggcgcgata gcttctgcca
    53461 gttcaatgtt cgctgcatag tcagaggtgt cggagaagac cacatcgtct tcaccgctct
    53521 gcgccagcac ctggaattcg tgagaggcgc tgccgccgat agaaccggtg tcggcttgta
    53581 cggcgcggaa atccagcccc atgcggctga agattttgct gtaggccgca tacattgcat
    53641 cgtaggtttc ctgcagggat tcctgagaag tatggaaaga gtaagcatct ttcatcagga
    53701 attcgcggga acgcatgacg ccgaaacgcg gacgcacttc gtcgcggaac ttggtctgga
    53761 tctgatagaa gttcagcggc agctgtttgt aagagctaag ctcgttacga atcaggtcag
    53821 tgataacttc ttcatgagtt gggccgagta cgaacggacg ctcgccacgg tcaacaaaac
    53881 gcagcagttc cggaccgtac tgttcccaac gaccactctc ttgccacaaa tcggctggct
    53941 gaaccaccgg catcgacacc tcgatcgcac cggcgttgtt catctcttca cgcacgatgt
    54001 tttcgacttt tttcagaacg cgcacgccgg tcggcagcca ggtatataac ccggaggcca
    54061 gcttgcggat catcccggcg cgcagcatca gctgatggct gatcacctcg gcgtcggcag
    54121 gtgtctcctt gagagtggag agcaggtatt ggctagtacg catgttgtta cggttccagt
    54181 tggaaggtag aacaggctca aggcgagcct gggacaaaaa aaagtgattt agtttaccag
    54241 tgcaaaagaa atgtcaaaag agaagggcgt gaatttaacg cggttccagc gcaaagactt
    54301 caaaacctgc gtcggtgacg cgccagcgaa cgttaaaatc atgtagccag acggcatagg
    54361 ttttgcccgt ttcctcacct ttacgatagg ccgggcgcgg gtcctgcgcc agtacttcgc
    54421 ggataaacag cgttaactgc ggataacgct tctccagcgt caaaagctgc ttttcgacct
    54481 ctgcggtaaa actcaccgcc atctctgcag ctggcgcact ttgcgcatag ctggcactgg
    54541 catcgggaag cgattcggca aaggggagat acggtttgat atccactacc ggcgtaccat
    54601 cgaccagatc cagactgccg agcttcagaa tcacgctgtc tttatggcaa acaacctctt
    54661 tcagctctac cagcgacatg ccaattgggt tagggcggaa agtagagcgt gttgcgaaaa
    54721 cccccattct ggcgttaccg ccaaggcgcg gtggacgcac agtcggacgc cagccgcctt
    54781 ccatcgtttg atgaaagacg aaaaggatcc ataaatggct gaacgcttcc aggccgcgaa
    54841 cggcgtcggc ctggttgtag ggagcaatga gatgcagttc gccgttggcg ctttttacca
    54901 gacctggctg gcgcggaacg gcgaactttt ctttataggg cgagcgaata acgcctattt
    54961 gctcgaactg gaaactgctc atttcgccgt aatgttaagc gcagaaccga tacatacagc
    55021 ctgacgatag cagcctggcg taccgctggt gacttcgcag ctatgcagta atacagcatt
    55081 ggctttcatt ttagaggcgt tgatttgcat ccgcttacgt gcggttggaa tgctcggcgg
    55141 agagtcctga ttagaggcct ggcaagagtc gccactgact tcaccgagat cgcggaacgg
    55201 tttgccgact aattcttctg cattggtata aattcggacc ggcgtggcgc gcggcgcttt
    55261 cggttttgca ggctccgctt tcggctgggg tgcagtgctt tgaacgggtt cgacagggga
    55321 tctgcttaac atggaacagc cgcttagcat gagtgctact aaacagatcg gtaaagcacg
    55381 catagtattt cctcaatgta tgatcaaaac gtcaatattg aatcaggagc ttgtaaaaat
    55441 gacaagacgg gcaagcgccc gtcctgaatg atattacaaa ttgtggaaac agcctaaaaa
    55501 ttaccagcct ttaacagctc cgccgttaaa cactttgttt gctgcttcgt aaacttcgtc
    55561 agactgataa gcctggacga atttcttcac gttctcggcg tctttgttat cttcacgcgt
    55621 cacgatcagg tttacgtacg gggactcttt atcttcaaca aagataccgt ctttcgccgg
    55681 agtcaggcca atctggctgg cataggtggt attgataact gccagagcga tttgcgcgtc
    55741 gtccagagaa cgcggcagtt gcggtgcttc cagttcaaca attttcagat ttttggggtt
    55801 ctcaacaaca tcaagaacgg tcggcagcag gccaacgcca tctttcagtt tgatcaagcc
    55861 cactttttgc agcagcagca gtgaacgacc aaggttagtt gggtcgtttg gcacggcaac
    55921 ctgcgaacca tcctgcagtt catccagtga tttgattttc ttggagtaac cagcaatcgg
    55981 ataaacaaaa gtgttgccta ctgcgaccag tttgtagcca cgatctttca gttgctgatc
    56041 aaggtacggt ttatgctgga aggcgttggc gtcgatatcg cctttgctca atgcttcgtt
    56101 tggcagaaca tagtcgttga aggttaccag ctcaacgtcc aggccatatt tgtctttcgc
    56161 aactttctgc gcgacttctg caacctgctg ttcggcacca acaatcacgc cgactttaat
    56221 gtggtttgga tctttttcat cctgaccgca gcctaccagt gccagtgatc cgatcagggc
    56281 tcccactgcc gcaaaggttt tgaatttgaa cgccatacct tattccttct tcaattattt
    56341 atgttgtgtt gaacgttact tgcgagtgac agcccggacg attcggtcgc ctgcgaactg
    56401 aattaaataa accagaatga ccagcaatac cagtaccgta ttcatcaccg tcgcgttata
    56461 gccgatgtag ccatactgat agccaatctg acctaaacca ccggcaccga ctgcaccacc
    56521 catcgcggaa taaccgacca gggtaatcag ggtgatagtt gccgcattca ccagacccgg
    56581 cagcgcttcc ggtaacagca ccttacggac gatctgcatc ggcgtggcac ccattgcgcg
    56641 ggaagcttca attaacccgg ttgggatctc cagcagagcg ttctcgacca tacgggcaat
    56701 aaacggtgct gcaccaacgg ttaacggaac aatcgctgcc tgcaaaccaa tcgatgtacc
    56761 gacaataacg cgggtaaacg gaatcatcca tacaagcaag ataatgaacg ggatggaacg
    56821 gaaaatgttc acaatcgcag aaacggtacg atacagcttc gcgttagcaa taatttgccc
    56881 cggacgcgtg acataaagca gaacgccaac cggcagacca atcacaaagc caaaaaaacc
    56941 ggatacgaag gtcattgcca gcgtttccca tacgccacga accagcagcc acatcatcgg
    57001 ctcagacata acccagtacc tctactttta catggtgttc ctgcagccag gcaatggcgg
    57061 cttgcgtatc ttgttgtgtg ccgtgcattt cagtcagcat gatgccgaac ttaacgccac
    57121 cggcgtaatc catctgcgcg ctaataatgt tgttgttgac gttgaaacga cgcgcggttt
    57181 cagaaagcag tggggcatcg accgattgac cggtaaactc cagacgcagc atcggcacgc
    57241 agtcagtaaa tggctccgct tgcagacgtt cctggtaatc ttccgggata tccagatgca
    57301 gggtcgactg aataaacttc tgcgccagcg gcgttttcgg atgcgagaac acttcactta
    57361 ccgtgtcctg ctcgatcagt tctccattgc tgatgaccgc cacgcaatca caaatgcgct
    57421 tcacaacgtc catttcgtgg gtgatcaaca gaatcgtcaa ccccagacgg cggttgatgt
    57481 ctttcagcag ttcgagaata gaacgtgtcg ttgccgggtc cagcgcgctg gtggcttcat
    57541 cacacagcaa tactttggga ttgctggcta acgcacgggc aattgccaca cgttgtttct
    57601 gcccaccgga aagattcgac gggtagctat catgcttatc gccaagacca accaatgaca
    57661 gcaattccgt cacgcgacgt ttgacctcgt ctttcggtgt gttgtccagc tccagcggca
    57721 gagccacgtt gccaaaaaca gtacgcgaag agagcaggtt aaaatgctgg aaaatcatac
    57781 caatctggcg gcgagctttg gtcaactcgg attctgacag cgtggtcagt tcctggccat
    57841 cgaccagcac gctaccctcg gttgggcgct ccagcaggtt tacacaacgt ataagcgtac
    57901 tcttacccgc gcctgaggca ccgataacgc cataaatttg tccagctggc acatgcaggc
    57961 tgacgttgtt caacgcctgg atggtgcggg tgccctggtg gaacactttg gtgatattcg
    58021 aaagttttat cattgattat ttattatcgt cattaagtta gtcgtggcat ctcgaatgcc
    58081 tgaaacgggc aacgccgtca atgaaatgga tgttaaggca tccagacgtc taaatcaatc
    58141 aggtttatgc gaagagcact ttcttgcagg tcgaaacatg cgatactagc gtcacatgcc
    58201 ttattaagga gctataaaag gtggcgaaga gcgtacccgc aatttttctt gaccgtgatg
    58261 gcaccattaa tgtcgatcac ggctatgtcc atgagatcga caactttgaa tttatcgacg
    58321 gtgttattga cgccatgcgc gagctaaaaa aaatgggctt tgcgctggtg gtagtaacca
    58381 accagtctgg cattgctcgc ggtaaattta ccgaagcaca gtttgaaacg ctgaccgagt
    58441 ggatggactg gtcgctggcg gaccgagatg tcgatctgga tggtatctat tattgcccgc
    58501 atcatccgca gggtagtgtt gaagagtttc gccaggtctg cgattgccgc aaaccacatc
    58561 cggggatgct tttgtcagca cgcgattatt tgcatattga tatggccgct tcttatatgg
    58621 tgggcgataa attagaagat atgcaggcag cggttgcggc gaacgtggga acaaaagtgc
    58681 tggtgcgtac gggtaaacct attacgcctg aagcagaaaa cgcggcggat tgggtgttaa
    58741 atagcctggc agacctgccg caagcgataa aaaagcagca aaaaccggca caatgattaa
    58801 aagatgagcg gttgaaataa aaatgcattt ttccgcttgt cttcctgagc cgactcccta
    58861 taatgcgcct ccatcgacac ggcggatgtg aatcacttca cacaaacagc cggttcggtt
    58921 gaagagaaaa atcctgaaat tcagggttga ctctgaaaga ggaaagcgta atatacgcca
    58981 cctcgcgaca gtgagctgaa agccgcgtcg caactgctct ttaacaattt atcagacaat
    59041 ctgtgtgggc actcgaagat acggattctt aacgtcgcaa gacgaaaaat gaataccaag
    59101 tctcaagagt gaacacgtaa ttcattac
//
LOCUS       DAPOAV010000019        56148 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.019, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000019 DAPOAV010000000
VERSION     DAPOAV010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 56148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56148
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.019"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(96..764)
                     /locus_tag="RN951_001407"
                     /pseudo
     CDS             complement(96..764)
                     /locus_tag="RN951_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313257.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(887..1339)
                     /gene="tabA"
                     /locus_tag="RN951_001408"
     CDS             complement(887..1339)
                     /gene="tabA"
                     /locus_tag="RN951_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin biofilm protein TabA"
                     /protein_id="HDX2526428.1"
                     /translation="MIIGNIHNLQPWLPQELRQAIEHIKAHVTPETPKGKHDIEGNRL
                     FYLISEDMTEPYEARRAEYHARYLDIQIVLRGQEGMTFSTQPAGTPDTDWLADKDIAF
                     LPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA"
     gene            complement(1484..2077)
                     /locus_tag="RN951_001409"
     CDS             complement(1484..2077)
                     /locus_tag="RN951_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709951.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDX2526429.1"
                     /translation="MVTKKQSRVPGRPRRFAPEQAVSAAKVLFHQKGFDAVSVAEVTD
                     YLGINPPSLYAAFGSKVGLFSRVLNEYVGTEAIPLADILRDDRPVGECLVEVLKEAAR
                     RYSQNGGCAGCMVLEGIHSHDPQARDIAVQYYHAAETTIYDYIARRHPQSAQCVTDFM
                     STVMSGLSAKAREGHSIEQLCATAALAGEAIKTILKE"
     gene            2148..2861
                     /gene="bdcA"
                     /locus_tag="RN951_001410"
     CDS             2148..2861
                     /gene="bdcA"
                     /locus_tag="RN951_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDX2526430.1"
                     /translation="MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAA
                     EHLAQETGATAVFTDSADRDAVIDVVRKSGALDILVVNAGIGVFGDALELNADDIDRL
                     FKINIHAPYHASVEAARQMPEGGRILIIGSVNSDRMPVAGMAAYAASKSALQGMARGL
                     ARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHSLMAIKRHGQPEEVAGMVAWLAG
                     PEASFVTGAMHTIDGAFGA"
     gene            2992..3387
                     /locus_tag="RN951_001411"
     CDS             2992..3387
                     /locus_tag="RN951_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDX2526431.1"
                     /translation="MVERTAVFPAGRHSLYAEHRYSAAIRSGDLLFVSGQVGSREDGT
                     PEPDFQQQVRLAFDNLHATLAAAGCTFDDIIDVTSFHTDPENQFEDIMTVKNEIFSAP
                     PYPNWTAVGVTWLAGFDFEIKVIARIPEQ"
     gene            3668..3802
                     /gene="pyrL"
                     /locus_tag="RN951_001412"
     CDS             3668..3802
                     /gene="pyrL"
                     /locus_tag="RN951_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyr operon leader peptide"
                     /protein_id="HDX2526432.1"
                     /translation="MVQCVRHFVLPRLKKDAGLPFFFPLITHSQPLNRGAFFCPGVRR
                     "
     gene            3806..4741
                     /gene="pyrB"
                     /locus_tag="RN951_001413"
     CDS             3806..4741
                     /gene="pyrB"
                     /locus_tag="RN951_001413"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HDX2526433.1"
                     /translation="MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKV
                     IASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDA
                     IVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAM
                     VGDLKYGRTVHSLTQALAKFDGNRFYFIAPDALAMPQYILDMLDEKGIAWSLHSSIEE
                     VMAEVDILYMTRVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIAT
                     DVDKTPHAWYFQQAGNGIFARQALLALVLNRDLVL"
     gene            4754..5215
                     /gene="pyrI"
                     /locus_tag="RN951_001414"
     CDS             4754..5215
                     /gene="pyrI"
                     /locus_tag="RN951_001414"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase regulatory
                     subunit"
                     /protein_id="HDX2526434.1"
                     /translation="MTHDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITI
                     GLNLPSGEMGRKDLIKIENTFLSEDQVDQLALYAPQATVNRIDNYEVVGKSRPSLPER
                     IDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVLAN"
     gene            5288..5674
                     /gene="ridA"
                     /locus_tag="RN951_001415"
     CDS             5288..5674
                     /gene="ridA"
                     /locus_tag="RN951_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418664.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminobutanoate/2-iminopropanoate deaminase"
                     /protein_id="HDX2526435.1"
                     /translation="MSKTIATENAPAAIGPYVQGVDLGNMIITSGQIPVNPKTGEVPA
                     DVAAQARQSLDNVKAIVEAAGLKVGDIVKTTVFVKDLNDFATVNATYEAFFTEHNATF
                     PARSCVEVARLPKDVKIEIEAIAVRR"
     gene            complement(5880..8576)
                     /gene="mgtA"
                     /locus_tag="RN951_001416"
     CDS             complement(5880..8576)
                     /gene="mgtA"
                     /locus_tag="RN951_001416"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HDX2526436.1"
                     /translation="MFKEIFTRLIRHLPSRLVHRDPLPGAQQTVNTVVPPSLSAHCLK
                     MAVMPEEELWKTFDTHPEGLNQAEVESAREQHGENKLPAQQPSPWWVHLWVCYRNPFN
                     ILLTILGAISYATEDLFAAGVIALMVAISTLLNFIQEARSTKAADALKAMVSNTATVL
                     RVINDKGENGWLEIPIDQLVPGDIIKLAAGDMIPADLRILQARDLFVAQASLTGESLP
                     VEKAATTRQPEHSNPLECDTLCFMGTTVVSGTAQAMVIATGANTWFGQLAGRVSEQES
                     EPNAFQQGISRVSMLLIRFMLVMAPVVLLINGYTKGDWWEAALFALSVAVGLTPEMLP
                     MIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTLTQDKIVLENHTDIS
                     GKTSERVLHSAWLNSHYQTGLKNLLDTAVLEGTDEESAHSLASRWQKIDEIPFDFERR
                     RMSVVVAENTEHHQLVCKGALQEILNVCSQVRHNGEIVPLDDIMLRKIKRVTDTLNRQ
                     GLRVVAVATKYLPAREGDYQRADESDLILEGYIAFLDPPKETTAPALKALKASGITVK
                     ILTGDSELVAAKVCHEVGLDAGEVVIGSDIETLSDDELANLAQRTTLFARLTPMHKER
                     IVTLLKREGHVVGFMGDGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLE
                     EGVIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFLPFLPMLPLHLLIQNLLYDVS
                     QVAIPFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLMWWVFHANTPET
                     QTLFQSGWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIMTVIVMIVGIALPFSPL
                     ASYLQLQALPLSYFPWLVAILAGYMTLTQLVKGFYSRRYGWQ"
     gene            complement(8717..8770)
                     /gene="mgtL"
                     /locus_tag="RN951_001417"
     CDS             complement(8717..8770)
                     /gene="mgtL"
                     /locus_tag="RN951_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003933616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mgtA regulatory leader peptide MgtL"
                     /protein_id="HDX2526437.1"
                     /translation="MEPDPTPLPRRRLKLFR"
     gene            8955..9902
                     /gene="treR"
                     /locus_tag="RN951_001418"
     CDS             8955..9902
                     /gene="treR"
                     /locus_tag="RN951_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator TreR"
                     /protein_id="HDX2526438.1"
                     /translation="MQNRLTIKDIARLSGVGKSTVSRVLNNESGVSQRTRERVEAVMN
                     QHGFSPSRSARAMRGQSDKVVAIIVTRLDSLSENLAVQTMLPAFYEQGYDPIMMESQF
                     SPQLVAEHLGILKRRNIDGVVLFGFTGITEEMLAHWQSSLVLLARDAKGFASVCYDDE
                     GAIKILMQRLYDQGHRNISYLGVPHSDVTTGKRRHEAYLAFCKAHKLHPVAALPGLAM
                     KQGYENVAKVITPETTALLCATDTLALGASKYLQEQRIDTLQLASVGNTPLMKFLHPE
                     IVTVDPGYAEAGRQAACQLIAQVTGRSEPQQIIIPATLS"
     gene            10021..11442
                     /gene="treB"
                     /locus_tag="RN951_001419"
     CDS             10021..11442
                     /gene="treB"
                     /locus_tag="RN951_001419"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS trehalose transporter subunit IIBC"
                     /protein_id="HDX2526439.1"
                     /translation="MMSKINQTDIDRLIELVGGRGNIATVSHCITRLRFVLNQPANAR
                     PKEIEQLPMVKGCFTNAGQFQVVIGTNVGDYYQALIASTGQAQVDKEQVKKAARQNMK
                     WHEQLISHFAEIFFPLLPALISGGLILGFRNVIGDLPMSNGQTLAQMYPSLQTIYDFL
                     WLIGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQQLPEVWDF
                     GMFSIAKVGYQAQVIPALLAGLALGVIETRLKRIVPDYLYLVVVPVCSLILAVFLAHA
                     LIGPFGRMIGDGVAFAVRHLMTGSFAPIGAALFGFLYAPLVITGVHQTTLAIDLQMIQ
                     SMGGTPVWPLIALSNIAQGSAVIGIIISSRKHNEREISVPAAISAWLGVTEPAMYGIN
                     LKYRFPMLYAMIGSGLAGLLCGLNGVMANGIGVGGLPGILSIQPSYWQVFALAMAIAI
                     IIPIVLTSFIYQRKYRLGTLDIV"
     gene            11492..13147
                     /gene="treC"
                     /locus_tag="RN951_001420"
     CDS             11492..13147
                     /gene="treC"
                     /locus_tag="RN951_001420"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709962.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HDX2526440.1"
                     /translation="MTNLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHK
                     LGVDAIWLTPFYVSPQVDNGYDVANYTAIDPTYGTLDDFDELVTQAKSRGIRIILDMV
                     FNHTSTQHAWFREALNKESPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYY
                     LHLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDPRFPEDLDGD
                     GRRFYTDGPRAHEFLHEMNRDVFTPRGLMTVGEMSSTSLEHCQRYAALAGSELSMTFN
                     FHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMHNVAWNALFWCNHDQPRIVSRFG
                     DEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESLNMFAELR
                     NDGRDADELLAILASKSRDNSRTPMQWSNGDNAGFTAGEPWIGLGDNYQQINVEAALA
                     DDSSVFYTYQKLIALRKQEAILTWGNYQDLLPNSPVLWCYRREWKGQTLLVIANLSRE
                     IQPWQPGQMRGNWQLVMHNYEEASPQPCAMNLRPFEAVWWLQK"
     gene            13541..15679
                     /gene="nrdD"
                     /locus_tag="RN951_001421"
     CDS             13541..15679
                     /gene="nrdD"
                     /locus_tag="RN951_001421"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HDX2526441.1"
                     /translation="MTPHVMKRDGCKVPFKSERIKEAILRAAKAAEVDDADYCATVAA
                     VVSEQMQGRNQVDINEIQTAVENQLMSGPYKQLARAYIEYRHDRDIEREKRGRLNQEI
                     RGLVEQTNASLLNENANKDSKVIPTQRDLLAGIVAKHYARQHLLPRDVVQAHERGDIH
                     YHDLDYSPFFPMFNCMLIDLKGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASH
                     IYGGTTINRIDEVLAPFVTASYNKHRKTAEEWSIPDAEGYANSRTIKECYDAFQSLEY
                     EVNTLHTANGQTPFVTFGFGLGTSWESRLIQESILRNRIAGLGKNRKTAVFPKLVFAI
                     RDGLNHKKGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVWE
                     NENGEQIHDGRNNLGVISLNLPRIALEAKGDEATFWKLLDERLVLARKALMTRIARLE
                     GVKARVAPILYMEGACGVRLNADDDVSEIFKNGRASISLGYIGIHETINALFGGEHVY
                     DNEQLRAKGIAIVERLRQAVDQWKEETGYGFSLYSTPSENLCDRFCRLDTAEFGVVPG
                     VTDKGYYTNSFHLDVEKKVNPYDKIDFEAPYPPLANGGFICYGEYPNIQHNLKALEDV
                     WDYSYQHVPYYGTNTPIDECYECGFTGEFECTSKGFTCPKCGNHDASRVSVTRRVCGY
                     LGSPDARPFNAGKQEEVKRRVKHLGNGQIG"
     gene            15837..16301
                     /gene="nrdG"
                     /locus_tag="RN951_001422"
     CDS             15837..16301
                     /gene="nrdG"
                     /locus_tag="RN951_001422"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate
                     reductase-activating protein"
                     /protein_id="HDX2526442.1"
                     /translation="MNYHQYYPVDIVNGPGTRCTLFVSGCVHECPGCYNKSTWRVNSG
                     QPFTKAMEDQIINDLNDTRIKRQGISLSGGDPLHPQNVPDILKLVKRIRAECPDKDIW
                     VWTGYKLDDLNAAQMQVVDLINVLVDGKFVQDLKDPSLIWRGSSNQVVHHLR"
     gene            complement(16346..16732)
                     /gene="cybC"
                     /locus_tag="RN951_001423"
     CDS             complement(16346..16732)
                     /gene="cybC"
                     /locus_tag="RN951_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313240.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b562"
                     /protein_id="HDX2526443.1"
                     /translation="MRKSLLAILAVSSLVFSSASFAADLEDNMETLNDNLKVVEKADN
                     AAQVKDALTKMRAAALDAQKATPPKLEGKSPDSPEMKDFRHGFDILVGQIDDALKLAN
                     EGKVKEAQAAAEQLKTTRNAYHQKYR"
     gene            complement(16787..18139)
                     /gene="pmbA"
                     /locus_tag="RN951_001424"
     CDS             complement(16787..18139)
                     /gene="pmbA"
                     /locus_tag="RN951_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease PmbA"
                     /protein_id="HDX2526444.1"
                     /translation="MALAMKVISQVEAQRKILEEAVSTALELASGKSDGAEVAVSKTT
                     GISVSTRYGEVENVEFNSDGALGITVYHQNRKGSASSTDLSPQAIARTVQAALDIARY
                     TSPDPCAGVADKELLAFDAPDLDLFHPAEVSPDEAIELAARAEQAALQADKRITNTEG
                     GSFNSHYGVKVFGNSHGMLQGYCSTRHSLSSCVIAEENGDMERDYAYTIGRAMSDLQT
                     PEWVGADCARRTLSRLSPRKLSTMKAPVIFANEVATGLFGHLVGAIAGGSVYRKSTFL
                     LDSLGKQILPDWLTIEEHPHLLKGLASTPFDSEGVRTERRDIIKDGILTQWLLTSYSA
                     RKLGLKSTGHAGGIHNWRIAGQGLSFEQMLKEMGTGLVVTELMGQGVSAITGDYSRGA
                     AGFWVENGEIQYPVSEITIAGNLKDMWRNIVTVGNDIETRSNIQCGSVLLPEMKIAGQ
                     "
     gene            18233..18784
                     /locus_tag="RN951_001425"
     CDS             18233..18784
                     /locus_tag="RN951_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein"
                     /protein_id="HDX2526445.1"
                     /translation="MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGA
                     EIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALD
                     KLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKE
                     GNKPPKSARQIFQYLRELAENEG"
     gene            complement(18940..20313)
                     /gene="mpl"
                     /locus_tag="RN951_001426"
     CDS             complement(18940..20313)
                     /gene="mpl"
                     /locus_tag="RN951_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-
                     meso-diaminopimelate ligase"
                     /protein_id="HDX2526446.1"
                     /translation="MRIHILGICGTFMGGLAMLARQLGHEVTGSDANVYPPMSTLLEK
                     QGIELIQGYDASQLDPQPDLVIIGNAMTRGNPCVEAVLEKNIPYMSGPQWLHDFVLRD
                     RWVLAVAGTHGKTTTAGMATWILEQCGYKPGFVIGGVPGNFEVSARLGESDFFVIEAD
                     EYDCAFFDKRSKFVHYCPRTLILNNLEFDHADIFDDLKAIQKQFHHLVRIVPGQGRII
                     WPENDINLKQTMAMGCWSEQELVGEQGHWQAKKLTTDASEWEVLLDGEKVGEVKWSLV
                     GEHNMHNGLMAIAAARHVGVAPADAANALGSFINARRRLELRGEANGVTVYDDFAHHP
                     TAILATLAALRGKVGGTARIIAVLEPRSNTMKMGICKDDLAPSLGRADEVFLLQPAHI
                     PWQVAEVAEACVQPAHWSGDVDTLADMVVKTAQPGDHILVMSNGGFGGIHQKLLDGLA
                     KKAEAAQ"
     gene            20489..21487
                     /gene="fbp"
                     /locus_tag="RN951_001427"
     CDS             20489..21487
                     /gene="fbp"
                     /locus_tag="RN951_001427"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 fructose-bisphosphatase"
                     /protein_id="HDX2526447.1"
                     /translation="MKTLGEFIVEKQHEFSHATGELTALLSAIKLGAKIIHRDINKAG
                     LVDILGASGAENVQGEVQQKLDLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEH
                     AKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVV
                     YGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVK
                     KYIKFCQEEDKSTNRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPDGKLRLLYEC
                     NPMAFLAEQAGGKASDGKERILDIIPETLHQRRSFFVGNDHMVEDVERFIREFPDA"
     gene            complement(21520..22515)
                     /gene="yjfF"
                     /locus_tag="RN951_001428"
     CDS             complement(21520..22515)
                     /gene="yjfF"
                     /locus_tag="RN951_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418652.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease YjfF"
                     /protein_id="HDX2526448.1"
                     /translation="MIKRNLPLMITIGVFVLGYFYCLTQFPGFASTRVICNILTDNAF
                     LGIIAVGMTFVILSGGIDLSVGSVIAFTGVFLAKVVGDFGLSPLLAFPLVLVMGCAFG
                     AFMGLLIDALKIPAFIITLAGMFFLRGVSYLVSEESIPINHPIYDTLSSLAWKIPGGG
                     RLSAMGLLMLAVVVIGIFLAHRTRFGNQVYAIGGNATSANLMGISTRSTTIRIYMLST
                     GLATLAGIVFSIYTQAGYALAGVGVELDAIASVVIGGTLLSGGVGTVLGTLFGVAIQG
                     LIQTYINFDGTLSSWWTKIAIGILLFIFIALQRGLTVLWENRQSSPVTRVNIAQR"
     gene            complement(22502..23524)
                     /locus_tag="RN951_001429"
     CDS             complement(22502..23524)
                     /locus_tag="RN951_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313234.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX2526449.1"
                     /translation="MPQSLPDTTPPKRRFRWPTGMPQLAALLLVLLVDSLVAPHFWQV
                     VLQDGRLFGSPIDILNRAAPVALLAIGMTLVIATGGIDLSVGAVMAIAGATTAAMTVA
                     GFSLPIVLLSALGTGILAGLWNGILVAILKIQPFVATLILMVAGRGVAQLITAGQIVT
                     FNSPDLSWFGSGSLLFLPTPVIIAVMTLLLFWLLTRKTALGMFIEAVGINIRAAKNAG
                     VNTRIIVMLTYVLSGLCAAIAGIIVAADIRGADANNAGLWLELDAILAVVIGGGSLMG
                     GRFNLLLSVVGALIIQGMNTGILLSGFPPEMNQVVKAVVVLCVLIVQSQRFISLIKGV
                     RSHDKT"
     gene            complement(23538..25040)
                     /locus_tag="RN951_001430"
     CDS             complement(23538..25040)
                     /locus_tag="RN951_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDX2526450.1"
                     /translation="MTTDQHQEILRTEGLSKFFPGVKALDNVDFSLRRGEIMALLGEN
                     GAGKSTLIKALTGVYHADRGTIWLEGQAISPKNTAHAQQLGIGTVYQEVNLLPNMSVA
                     DNLFIGREPKRFGFLRRKEMEKRATELMTSYGFSLDVREPLNRFSVAMQQIVAICRAI
                     DLSAKVLILDEPTASLDTQEVELLFGLMRQLRDRGVSLIFVTHFLDQVYQVSDRITVL
                     RNGSFVGCRETRELPQIELVKMMLGRELDTHALQRAGRTLLSDKPVAAFKNYGKKGTI
                     APFDLEVRPGEIVGLAGLLGSGRTETAEVIFGIKPADSGTALIKGKPQNLRSPHQASV
                     LGIGFCPEDRKTDGIIAAASVRENIILALQAQRGWLRPISRKEQQEIAERFIRQLGIR
                     TPSTEQPIEFLSGGNQQKVLLSRWLLTRPQFLILDEPTRGIDVGAHAEIIRLIETLCA
                     DGLALLVISSELEELVGYADRVIIMRDRKQVAEIPLAELSVPAIMNAIAA"
     gene            complement(25350..26306)
                     /gene="ytfQ"
                     /locus_tag="RN951_001431"
     CDS             complement(25350..26306)
                     /gene="ytfQ"
                     /locus_tag="RN951_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactofuranose ABC transporter
                     substrate-binding protein YtfQ"
                     /protein_id="HDX2526451.1"
                     /translation="MWKRLLVVSAVSAAMSSMALAAPLTVGFSQVGSESGWRAAETNV
                     AKSEAEKRGITLKIADGQQKQENQIKAVRSFVAQGVDAIFIAPVVATGWEPVLKEAKD
                     AEIPVFLLDRSIDVKDKSLYMTTVTADNILEGKLIGDWLVKEVNGKPCNVVELQGTVG
                     ASVAIDRKKGFAEAIKNAPNIKIIRSQSGDFTRSKGKEVMESFIKAENNGKNICMVYA
                     HNDDMVIGAIQAIKEAGLKPGKDILTGSIDGVPDIYKAMIDGEANASVELTPNMAGPA
                     FDALEKYKKDGTMPEKLTLTKSTLYLPDTAKEELEKKKNMGY"
     gene            26616..27146
                     /gene="ppa"
                     /locus_tag="RN951_001432"
     CDS             26616..27146
                     /gene="ppa"
                     /locus_tag="RN951_001432"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001739810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic diphosphatase"
                     /protein_id="HDX2526452.1"
                     /translation="MSLLNVPAGKDLPEDIYVVIEIPANADPIKYEIDKESGALFVDR
                     FMSTAMFYPCNYGYINHTLSLDGDPVDVLVPTPYPLQPGSVIRCRPVGVLKMTDEAGE
                     DAKLIAVPHTKLSKEYDHIKDVNDLPELLKAQIAHFFEHYKDLEKGKWVKVEGWENAE
                     AAKAEIVASFERAKNK"
     gene            complement(27226..27576)
                     /gene="chpB"
                     /locus_tag="RN951_001433"
     CDS             complement(27226..27576)
                     /gene="chpB"
                     /locus_tag="RN951_001433"
                     /EC_number="4.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease toxin ChpB"
                     /protein_id="HDX2526453.1"
                     /translation="MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLG
                     MTLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLVNQVRMMDLRARLAKRIGLAADE
                     VVEEALLRLQAVVE"
     gene            complement(27570..27821)
                     /gene="chpS"
                     /locus_tag="RN951_001434"
     CDS             complement(27570..27821)
                     /gene="chpS"
                     /locus_tag="RN951_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418645.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin ChpS"
                     /protein_id="HDX2526454.1"
                     /translation="MRITIKRWGNSAGMVIPNIVMKELNLQPGQSVEAQVSNNQLILT
                     PISRRYSLDELLAQCDMNAAELSEQDVWGKSTPAGDEIW"
     gene            complement(28034..28375)
                     /locus_tag="RN951_001435"
     CDS             complement(28034..28375)
                     /locus_tag="RN951_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcyclotransferase"
                     /protein_id="HDX2526455.1"
                     /translation="MRIFVYGSLRHKQGNSHWMTNAQLLGDFSIDNYQLYSLGHYPGA
                     VPGNGTVHGEVYRIDNATLAELDALRTRGGEYARQLIQTPYGSAWMYVYQRPVDGLKL
                     IESGDWLDRDK"
     gene            complement(28378..32157)
                     /gene="tamB"
                     /locus_tag="RN951_001436"
     CDS             complement(28378..32157)
                     /gene="tamB"
                     /locus_tag="RN951_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamB"
                     /protein_id="HDX2526456.1"
                     /translation="MSLWKKISLGVVIVILLLLGSVAFLVGTTSGLHLVFKAADRWVP
                     GLDIGKVTGGWRDLTLSDVRYEQPGVAVKAGNLHLAVGLECLWNSSVCINDLALKDIQ
                     VNIDSKKMPPSEQVEEEEDSGPLDLSTPYPITLTRVALDNVNIKIDDTTVSVMDFTSG
                     LNWQEKTLTLKPTSLKGLLIALPKVAEVAQEEVVEPKIENPQPEEKPLGETLKDLFSR
                     PVLPEMTDLHLPLNLNIEEFKGEQLRVTGDTDITVRTMLLKVSSIDGNTKLDALDIDS
                     NQGIVNASGTAQLSDNWPVDITLNSTLNVEPLKGEKVKLKVGGALREQLEIGVNLSGP
                     VDMDLRAQTRLAEAGLPLNVEVNSKQLYWPFTGEKQYQADDLKLKLTGKMTDYTLSMR
                     TAVKGQEIPPATITLDAKGNEQQVNLDKLTVAALEGKTELKALLDWQQAISWRGELTL
                     NGINTAKEFPEWPSKLNGLIKTRGSLYGGTWQMEVPELKLTGNVKQNKVNVDGTLKGN
                     SYMQWMIPGLHLELGPNSAEVKGELGVKDLNLDATINAPGLDNALPGLGGTAKGLVKV
                     RGTVEAPQLLADITARGLRWQELSVAQVRVEGDIKSTDQIAGKLDVRVEQISQPDVNI
                     NLVTLNAKGSEKQHELQLRIQGEPVSGQLNLAGSFDRKEERWKGTLSNTRFQTPVGPW
                     SLTRDIALDYRNKEQKISIGPHCWLNPNAELCVPQTIDAGAEGRAVVNLNRFDLAMLK
                     PFMPETTQASGIFTGKADVAWDTTKEGLPQGSITLSGRNVQVTQTVNDAALPVAFQTL
                     NLTAELRNNRAELGWTIRLTNNGQFDGQVQVTDPQGRRNLGGNVNIRNFNLAMINPIF
                     TRGEKAAGMVSANLRLGGDVQSPQLFGQLQVTGVDIDGNFMPFDMQPSQLAVNFNGMR
                     STLAGTVRTQQGEIYLNGDADWSQIENWRARVTAKGSKVRITVPPMVRMDVSPDVVFE
                     ATPNLFTLDGRVDVPWARIVVHDLPESAVGVSSDVVMLNDNLQPEEPKTASIPINSNL
                     IVHVGNNVRIDAFGLKARLTGDLNVVQDKQGLGLNGQINIPEGRFHAYGQDLIVRKGE
                     LLFSGPPDQPYLNIEAIRNPDATEDDVIAGVRVTGLADEPKAEIFSDPAMSQQAALSY
                     LLRGQGLESDQSDSAAMTSMLIGLGVAQSGQIVGKIGETFGVSNLALDTQGVGDSSQV
                     VVSGYVLPGLQVKYGVGIFDSIATLTLRYRLMPKLYLEAVSGVDQALDLLYQFEF"
     gene            complement(32154..33887)
                     /gene="tamA"
                     /locus_tag="RN951_001437"
     CDS             complement(32154..33887)
                     /gene="tamA"
                     /locus_tag="RN951_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamA"
                     /protein_id="HDX2526457.1"
                     /translation="MRYIRQLCCVSLLCLSGSAVAANVRLQVEGLSGQLEKNVRAQLS
                     TIESDEVTPDRRFRARVDDAIREGLKALGYYQPTIEFDLRPPPKKGRQVLIAKVTPGV
                     PVLIGGTDVVLRGGARTDKDYLKLLDTRPAIGTVLNQGDYENFKKSLTSIALRKGYFD
                     SEFTKAQLGIALGLHKAFWDIDYNSGERYRFGHVTFEGSQIRDEYLQNLVPFKEGDEY
                     ESKDLAELNRRLSATGWFNSVVVAPQFDKARETKVLPLTGVVSPRTENTIETGVGYST
                     DVGPRVKATWKKPWMNSYGHSLTTSTSISAPEQTLDFSYKMPLLKNPLEQYYLVQGGF
                     KRTDLNDTESDSTTLVASRYWDLSSGWQRAINLRWSLDHFTQGEITNTTMLFYPGVMI
                     SRTRSRGGLMPTWGDSQRYSIDYSNTAWGSDVDFSVFQAQNVWIRTLYDRHRFVTRST
                     LGWIETGDFDKVPPDLRFFAGGDRSIRGYKYKSIAPKYANGDLKGASKLITGSLEYQY
                     NVTGKWWGAVFVDSGEAVSDIRRSDFKTGTGVGVRWESPVGPIKLDFAVPVADKDEHG
                     LQFYIGLGPEL"
     gene            34093..34731
                     /gene="msrA"
                     /locus_tag="RN951_001438"
     CDS             34093..34731
                     /gene="msrA"
                     /locus_tag="RN951_001438"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDX2526458.1"
                     /translation="MSLFDKKHLVSPADALPGRNTPMPVATLHAVNGHSMTNVPDGME
                     IAIFAMGCFWGVERLFWQLPGVYSTAAGYTGGYTPNPTYREVCSGDTGHAEAVRIVYD
                     PSVISYEQLLQVFWENHDPAQGMRQGNDHGTQYRSAIYPLTPEQDAAARASLERFQAA
                     MLAADDDRHITTEIANATPFYYAEDDHQQYLHKNPYGYCGIGGIGVCLPPEA"
     gene            35054..36397
                     /locus_tag="RN951_001439"
     CDS             35054..36397
                     /locus_tag="RN951_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDX2526459.1"
                     /translation="MLNSILVILCLIAVSAFFSMSEISLAASRKIKLKLLADEGNINA
                     QRVLNMQENPGMFFTVVQIGLNAVAILGGIVGDAAFSPAFHSLFSRYMSAELSEQLSF
                     ILSFSLVTGMFILFADLTPKRIGMIAPEAVALRIINPMRFCLYVCTPLVWFFNGLANI
                     IFRIFKLPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTP
                     RENVIWFDLHEDEQSLKNKVAEHPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSLA
                     LNSGVQIRNTLIVPDTLTLSEALESFKTAGEDFAVIMNEYALVVGIITLNDVMTTLMG
                     DLVGQGLEEQIVARDENSWLIDGGTPIDDVMRVLDIDEFPQSGNYETIGGFMMFMLRK
                     IPKRTDSVKFAGYKFEVVDIDNYRIDQLLVTRIDSKATALSPKLPDAKDKEESVA"
     gene            complement(36459..36665)
                     /locus_tag="RN951_001440"
     CDS             complement(36459..36665)
                     /locus_tag="RN951_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1107 domain-containing protein"
                     /protein_id="HDX2526460.1"
                     /translation="MKIFQRYNPLQVAKYVKILFRGRLYIKDVGAFEFDKGKILIPKV
                     KDKLHLSVMSEVNRQVMRLQTEMA"
     gene            36990..37547
                     /locus_tag="RN951_001441"
     CDS             36990..37547
                     /locus_tag="RN951_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001498728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtfJ family protein"
                     /protein_id="HDX2526461.1"
                     /translation="MTLRKILALTCLLLPMMASAHQFETGQRVPPIGITDRGELVLDK
                     DQFSYKTWNSAQLVGKVRVLQHIAGRTSAKEKNATLIEAIKSAKLPHDRYQTTTIVNT
                     DDAIPGSGMFVRSSLESNKKLYPWSQFIVDSNGVARGAWQLDEESSAVVVLDKDGRVQ
                     WAKDGALTQEEVQQVMDLLHKLINK"
     gene            complement(37537..38277)
                     /gene="cysQ"
                     /locus_tag="RN951_001442"
     CDS             complement(37537..38277)
                     /gene="cysQ"
                     /locus_tag="RN951_001442"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'(2'),5'-bisphosphate nucleotidase CysQ"
                     /protein_id="HDX2526462.1"
                     /translation="MLDQVCQLARNAGDAIMQVYDGTKPMDVVSKADNSPVTAADIAA
                     HTVIMDGLRTLTPDIPVLSEEDPPGWEVRQHWQRYWLVDPLDGTKEFIKRNGEFTVNI
                     ALIDHGKPILGVVYAPVMNIMYSAAEGKAWKEECGVRKQIQVRDARPPLVVISRSHAD
                     AELKEYLQQLGEHQTTSIGSSLKFCLVAEGQAQLYPRFGPTNIWDTAAGHAVAAAAGA
                     HVHDWQGKPLDYTPRESFLNPGFRVSIY"
     gene            38467..40410
                     /gene="cpdB"
                     /locus_tag="RN951_001443"
     CDS             38467..40410
                     /gene="cpdB"
                     /locus_tag="RN951_001443"
                     /EC_number="3.1.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2',3'-cyclic-nucleotide 2'-phosphodiesterase"
                     /protein_id="HDX2526463.1"
                     /translation="MIKFSATLLATLIAASVNAATVDLRIMETTDLHSNMMDFDYYKD
                     TATEKFGLVRTASLINDARNEVKNSVLVDNGDLIQGSPLADYISAKGLKAGDVHPVYK
                     ALNTLDYTVGTLGNHEFNYGLDYLKNALAGAKFPYVNANVIDARTKQPMFTPYLIKDT
                     EVVDKDGKKQTLKIGYIGVVPPQIMGWDKANLSGKVTVNDITETVRKYVPEMREKGAD
                     VVVVLAHSGLSADPYKVMAENSVYYLSEIPGVNAIMFGHAHAVFPGKDFADIEGADIA
                     KGTLNGVPAVMPGMWGDHLGVVDLQLSNNSGKWQVTQAKAEARPIYDIANKKSLAAED
                     SKLVETLKADHDATRQFVSKPIGKSADNMYSYLALVQDDPTVQVVNNAQKAYVEHYIQ
                     GDPDLAKLPVLSAAAPFKVGGRKNDPASYVEVEKGQLTFRNAADLYLYPNTLIVVKAS
                     GKEVKEWLECSAGQFNQIDPDNTKPQSLINWDGFRTYNFDVIDGVNYQIDVTQPARYD
                     GECQMVNANAERIKNLTFNGKPIDPNAMFLVATNNYRAYGGKFAGTGDSHIAFASPDE
                     NRSVLAAWIADESKRAGEIHPAADNNWRLAPIAGDKKLDIRFETSPSDKAAAFIKEKG
                     QYPMNKVATDDIGFAIYQVDLSK"
     gene            complement(40533..40913)
                     /locus_tag="RN951_001444"
     CDS             complement(40533..40913)
                     /locus_tag="RN951_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418633.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDX2526464.1"
                     /translation="MSQVSLSQQLKEGNLFAEQCPSREVLKHVTSRWGVLILVALREG
                     THRFSDLRRKIGGVSEKMLAQSLQALEQDGFLNRIAYPVVPPHVEYSLTPLGEQVSEK
                     VAALADWIELNLPEVLAVRDERAA"
     gene            41002..41862
                     /gene="qorB"
                     /locus_tag="RN951_001445"
     CDS             41002..41862
                     /gene="qorB"
                     /locus_tag="RN951_001445"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001491469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H:quinone oxidoreductase"
                     /protein_id="HDX2526465.1"
                     /translation="MIAITGATGQLGHYVIKSLMKTVPASQIVAIVRNPAKAQALTAQ
                     GITVRQADYGDEAALTSALQGVEKLLLISSSEVGQRAPQHRNVINAAKTAGVKFIAYT
                     SLLHADKSPLGLADEHIETEKMLADSGIVYTLLRNGWYTENYLASAPAALEHGVFIGA
                     AGDGKIASATRADYAAAAARVISEAGHEGKVYELAGDSAWTLTQLAAELTKQSGKQVT
                     YQNLSETDFAAALKSVGLPDGLADMLADSDVGASKGGLFDDSKTLSKLIGRPTTTLAE
                     SVSHLFNVNK"
     gene            41971..42936
                     /locus_tag="RN951_001446"
     CDS             41971..42936
                     /locus_tag="RN951_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709987.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDX2526466.1"
                     /translation="MISGVLYALLAGLMWGLIFVGPLIVPEYPAMLQSMGRYLALGLI
                     ALPIAWLGRVRLRQLARRDWLTALMLTMMGNLIYYFCLASAIQRTGAPVSTMIIGTLP
                     VVIPVFANLLYSQRDGKLAWGKLAPALICIGIGLACVNIAELNHGLPDFDWARYTSGI
                     VLALVSVVCWAWYALRNARWLRENPDKHPMMWATAQALVTLPVSLIGYLVACYWLNIQ
                     TPDFSLPFGPRPLVFISLMVAIAVLCSWVGALCWNVASQRLPTVILGPLIVFETLAGL
                     LYTFLIRQQMPPLMTLSGIALLVVGVVIAVRAKPEKPLTESVSES"
     gene            43044..43706
                     /gene="ytfE"
                     /locus_tag="RN951_001447"
     CDS             43044..43706
                     /gene="ytfE"
                     /locus_tag="RN951_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster repair protein YtfE"
                     /protein_id="HDX2526467.1"
                     /translation="MAYRDQPLGELALSIPRASALFRKYDMDYCCGGKQTLARAAARK
                     ELDVEVIEAELAKLAEQPIEKDWRSAPLAEIIDHIIVRYHDRHREQLPELILQATKVE
                     RVHADKPSVPKGLTKYLTMLHEELSSHMMKEEQILFPMIKQGMGSQAMGPISVMESEH
                     DEAGELLEVIKHTTNNVTPPPEACTTWKAMYNGINELIDDLMDHISLENNVLFPRALA
                     GE"
     gene            complement(43751..45163)
                     /gene="cycA"
                     /locus_tag="RN951_001448"
                     /gene_synonym="dagA"
     CDS             complement(43751..45163)
                     /gene="cycA"
                     /locus_tag="RN951_001448"
                     /gene_synonym="dagA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine/D-alanine/glycine transporter"
                     /protein_id="HDX2526468.1"
                     /translation="MVDQVKVVADDQAPAEQSLRRNLTNRHIQLIAIGGAIGTGLFMG
                     SGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASDLLGPWAGYF
                     TGWTYWFCWVVTGMADVVAITAYAQFWFPDLSDWVASLAVIVLLLTLNLATVKMFGEM
                     EFWFAMIKIVAIVSLIVVGLVMVAMHFQSPTGVEASFAHLWNDGGWFPKGLSGFFAGF
                     QIAVFAFVGIELVGTTAAETKDPEKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSV
                     VPEKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPKA
                     FAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIGAFTMITTVSAILFMFVWTIILC
                     SYLVYRKQRPHLHEKSIYKMPLGKLMCWVCMAFFVFVVVLLTLEDDTRQALLVTPLWF
                     IALGLGWLFIGKKRAAELRK"
     gene            complement(45472..46092)
                     /gene="fklB"
                     /locus_tag="RN951_001449"
     CDS             complement(45472..46092)
                     /gene="fklB"
                     /locus_tag="RN951_001449"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015742582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDX2526469.1"
                     /translation="MTTPTFDTIEAQASYGIGLQVGQQLSESGLQGLLPEALVAGIAD
                     ALEGKHPAVPVDVVHRALREIHERADAVRRQRFQAMAAEGVKYLEENAKKEGVNSTES
                     GLQFRVINQGEGAIPARTDRVRVHYTGKLIDGTVFDSSVARGEPAEFPVNGVIPGWIE
                     ALTLMPVGSKWELTIPQELAYGERGAGASIPPFSTLVFEVELLEIL"
     gene            46311..46949
                     /gene="ytfB"
                     /locus_tag="RN951_001450"
     CDS             46311..46949
                     /gene="ytfB"
                     /locus_tag="RN951_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418627.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein YtfB"
                     /protein_id="HDX2526470.1"
                     /translation="MPGRFELKPTLEKVWHAPDNFRFMDPLPPMHRRGIIIAAIILVV
                     GFLLPSDDTPNAPVVTREAQLDIQSQSQPPTEEQLRAQLVTPQNDPDQVAPVAPEPIQ
                     EGQPEEQPQTTQTQPFQPDSGIDNQWRSYRVEPGKTMAQLFRDHGLPATDVYAMAQVE
                     GAGKPLSNLQNGQMVKIRQNASGVVTGLTIDTGNNQQVLFTRQPDGSFIRAR"
     gene            complement(46933..47580)
                     /locus_tag="RN951_001451"
     CDS             complement(46933..47580)
                     /locus_tag="RN951_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709992.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HDX2526471.1"
                     /translation="MYLDTSNVQSLKEKLLLCAVNEFAEYGYEGARVDNIVKAAGCSK
                     QTVYHHFGNKENLFIEVLEYTWNDIRQKEKALDFSDLPPQKAIEKIIDFTWDYYIANP
                     WFLKIVHSENQSKGVHYAKSQRLLEINHAHLQLMESLLDEGKKHNIFKPDIDPLQVNI
                     NIAALGGYYLINQHTLGLVYHISMVSPQALEARRKVIKETILSWLLVDPSSTAHE"
     gene            47793..48584
                     /locus_tag="RN951_001452"
     CDS             47793..48584
                     /locus_tag="RN951_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709993.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-ketoacyl-ACP reductase"
                     /protein_id="HDX2526472.1"
                     /translation="MKSTRPVAVITGAARGIGKGCALELARGGFNLLINDLPDADSVE
                     KLHITQQECIAEGVEVICFPADVGDLSLHEEMLDAAQNLWGRLDCLLNNAGISVKKRG
                     DLLDLEPDSFDQNIAINTRAPFFLAQAFSKRLLAQPKPEAELPHRSIIFVSSINAIML
                     AMNRGEYTIAKTAVSAAARLFAARLCNEQIGVYEVRPGLIKTDMTIPATAYYDELIAK
                     GLVPWGRWGYPADIASTVRAMAEGKLIYTCGQAVAIDGGLSMPRF"
     gene            48594..49436
                     /locus_tag="RN951_001453"
     CDS             48594..49436
                     /locus_tag="RN951_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDX2526473.1"
                     /translation="MRDLLQRPDLFSINTATLGYKTPLPAIIDACAARGIGAIAPWRR
                     ELQGEDLQQIAHQLAASNMSVSGLCRSTYYTAPTLAERKLAIDDNRRALDDAAVLNAA
                     CYMQVVGGLPTGTKDLYEAREQVKQGIRQLLPHSKDVGVPIALEPLHPMTAADRSCLC
                     TLRQALDWCDELDPDGEFGLGVAVDVYHVWWDPDLASQILRAGKRILAFHVSDWLVPT
                     TDLVNDRGMPGDGVINIPSIRRLVENAGFNGAIELEIFSPYWWQKDINSTLDISVDRI
                     AHYC"
     gene            49446..50222
                     /locus_tag="RN951_001454"
     CDS             49446..50222
                     /locus_tag="RN951_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDX2526474.1"
                     /translation="MSDQPVLFSRAAASCRLTLNREDKCHAINEEMIESLDHYLNEIE
                     NDTTLRLVELTATGDKFFCAGGDIKSWSAYSPLDMGRKWIKRGNDVFNRLRNLPQLTV
                     ANLNGHTIGGGIELALCCDIRIARPGAKFSNPEVMLGMVPGWMGIERVLNQVGPVVGR
                     QMLMLGKRLTAQEAQAANLIDEVVEKEQVESWMANQLAQLEKCGPVALAHIKQLILAL
                     ENKHADYPHQLLAGLMSATQDCQQATRAFAEKSSVRFHNQ"
     gene            50232..51773
                     /locus_tag="RN951_001455"
                     /pseudo
     CDS             50232..51773
                     /locus_tag="RN951_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226973.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyl CoA:acetate/3-ketoacid CoA transferase"
     gene            51770..53851
                     /locus_tag="RN951_001456"
     CDS             51770..53851
                     /locus_tag="RN951_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005766390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HDX2526475.1"
                     /translation="MSQLDDTILDALTHVTFPKGFAQAEPAWVVTVDGVDYPLWQTDA
                     LVVGSGAAGLRAAVELKRRQQNVLIATAGLYMGTSACSGSDKQTLFTAATAGNGDNFT
                     KLAEALASGGAMDHDTAYVEAVGSLHTLGGLQYLGLELPEDRYGAILRYQTDHDEAGR
                     ATSCGPRTSRLMVKVLLEEVQRLAIPVLTSATVIKLLHQRDENGEDRVAGAILATGHR
                     AHNPWGLAIVTAPNVVLATGGPGELYRDSVYPHKCFGSLGLALEEGLTLTNLTESQFG
                     IGTPRSTFPWNLSGTYVQVIPYIYSVDAEGNEYNFLADYYRTTQELASNIFRKGYQWP
                     FHATRVMDFGSSLLDMAVAQEQQSGRQVFMDFNRNPEAVPGDLPFSLDRLDDDVRAYL
                     ENNDALAPSPIERLQRMNPLSISLYKMHGYDLTTQPLQFAMNNQHMNGGIEVDIWGQT
                     SLPGCFAVGEVAGTHGVTRPGGAALNAGQVFAVRLARFIGCTQKRNIDGDIAQLVAPT
                     LASIREIITQAHDNGTGMPLSVVREKIQARMSDHAGFICHADKVRRATRDALLLSEFV
                     QRHGLAIKHVGEVAELFMWRHMALTSAAVLTQLTHYIDAGGGSRGARIILDRDGNSIP
                     QTRNGFCDAWRFRSERTEDKKDKLLIHYCNGIFHVRETPIREFPIIRGIWFEKNWPGF
                     LNGTIYQPQDE"
     gene            53872..54348
                     /locus_tag="RN951_001457"
     CDS             53872..54348
                     /locus_tag="RN951_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012311688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HDX2526476.1"
                     /translation="MRNIIKSINALLAALNITILAIIVACVTWQVAARFIFTSPSIFT
                     DELSRLLFICLGLFGGAYTAGQNRHLAIDLLPMMLKGKARRHLFLCIQIIVIIFATII
                     MVYGGGLLTMDTFDSGQTSPALGWQMGYIYMSIPISGVLIIIYTIDMVLTELKQPL"
     gene            54391..55692
                     /locus_tag="RN951_001458"
     CDS             54391..55692
                     /locus_tag="RN951_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HDX2526477.1"
                     /translation="MDYWLPIIVLFGAFFFMLALGVPIVYAIGLSTLASISTQLDFNS
                     ALSVVSQKLASGLDSFTLLAIPFFILSGNIMNHGGIARRLINFARILGGRLPGSLAHC
                     NILANMLFGAISGSAVASAAAMGGVMHPQQVKEGYDPAFSTAVNVASAPTGLLIPPSN
                     TLIVYSLVSGGTSIAALFLAGYVPGILLGLALMVIAGIIAVRRGYPKPERPTLRQAGV
                     AIWMAIPSIFLIILIMGGVLSGIFTPTEASAIAVIYTLFLALVLYREISVKDLPKIFL
                     ESVITTAIVLLLIGSSMGMSWAMSNADVPFLILDLLNTISDNPIIILLIINIILLIIG
                     TFMDMTPAVLIFTPIFLPVVTELGMDPIHFGIVMVLNMCIGICTPPVGSVLFVGCSVS
                     KLPINKIIKPMLPFYAVMVLVLAMVTYIPQISMALPRALGY"
     gene            55745..56143
                     /gene="dctP"
                     /locus_tag="RN951_001459"
                     /pseudo
     CDS             55745..56143
                     /gene="dctP"
                     /locus_tag="RN951_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001422748.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein DctP"
BASE COUNT        13726 a        14746 c        14092 g        13584 t
ORIGIN      
        1 tcaattttgg tatcatgtaa cgttttcaga ccatttattt cttcaagtat accaccttcg
       61 cctagtaagt atggaatcgt gtcatcacat acatgaggca ttaatagcag atgttctttc
      121 tttatttttt ctaatgtact ggctaatggc ttttctaata actcgttata atcaattgcg
      181 tccttccagt tcaactgatg attatttaat agaagcgcca cttccttgtt agcttcacgt
      241 tgataacacg ccagaacctt gttagtaatc aggtgtaatg aactctcatc ttttctttca
      301 aaggactttc cttcataacg attagtcgaa ccatcaggtt gttgaaatat aatagccgta
      361 tgtccttgac gagtccccat agtagtgata gtggaaagtg taatttctat ttccacctta
      421 gataaatccg ctcgctcccc ttcaggatta ttcataacaa acttcattat ctcactgcca
      481 tcattatttt tgatataaga tgaggactca atatgagcca tcatatttct tcccgcttcg
      541 ttggagcggt tgctaaaatc cacataaccc agggtaaata tttttaccaa aaactctaaa
      601 aatgtcttag gatcgaggat atttcttgta ttatcctgcc cctcggcatt acgagcaaaa
      661 ttattcattc caacacgcca ggtatttaaa acttcacttt tttgtttaaa attgtcggct
      721 aatgtaatgt gttgagaata attcaaatct gatattttgc tcatgacgga ctccttgagt
      781 taataagaac gtctaagcat tacaaatttt actcacaaaa aaatatcaaa aaacgctctt
      841 ttcacaaact cgccgtaaac ctggtgttat ttacggcgaa aagtcatcac gccatcagca
      901 tcttcactac tgctttgcga acctgggctg gtgcgcccac tgcgcacagc ggtttatgca
      961 cttcccccgg ataaaacaca acaaaatcac cttcatttag gataactgtt ttctcatcaa
     1021 cgccttccgg caaaaatgcg atgtctttat cagctaacca gtcggtatcc ggcgtgcctg
     1081 caggttgcgt gctgaaggtc atgccttcct gacctcttaa cacaatctga atgtcgagat
     1141 agcgggcatg gtactccgca cggcgagctt cgtacggctc ggtcatatct tccgagataa
     1201 gataaaacag acgattgcct tcgatatcgt gcttaccctt tggcgtttct ggcgtaacgt
     1261 gcgctttgat atgctcaatc gcctggcgta actcctgggg tagccacggc tgaagattat
     1321 gaatatttcc aatgatcatc ttttccactc tttaattaaa acaatgtttc atttctatcg
     1381 ttatacgaaa agatgatcaa ttccgctagc cttaacgcgt gaattattgt cttatcacaa
     1441 cttatcggca ggcgcgttcc cgcctttcgg gtcaaggcca gcatcactcc ttgagaatag
     1501 tttttatcgc ttcccccgcc agtgcagctg ttgcacagag ttgttcgatg gagtgcccct
     1561 cccgtgcctt cgcagaaagc cctgacatca cggtactcat aaaatcagtc acacattgtg
     1621 cgctttgtgg atgccgcctg gcgatatagt cataaatggt cgtttctgcg gcgtgataat
     1681 attgaacggc aatatcacgc gcttgtggat catgactatg aataccttca agaaccatac
     1741 agccagcgca gccgccgttt tggctatatc tgcgcgccgc ttcttttaat acctcaacca
     1801 ggcactcgcc taccggacga tcatcacgaa gaatatcggc aagcggaata gcttccgtac
     1861 cgacatattc attgagtaca cggctaaata acccaacttt actgccaaaa gctgcgtaga
     1921 ggctcggggg gttaatacca agataatcag taacttcagc aacactgaca gcatcgaaac
     1981 ctttttggtg aaaaagcact tttgccgcag agactgcctg ctcaggagcg aaacgtctgg
     2041 gacgacctgg aacgcgagat tgttttttag tgaccattac aaaacttgtt gacagaaagt
     2101 taaaacagtt ttgtaatgca tgttacataa taaatcaagg agtccttatg ggcgctttta
     2161 caggtaagac agttctcatc ctcggtggca gtcgtggaat cggtgccgct atcgtacgtc
     2221 gtttcgtcac tgatggggcc aatgtacgat tcacctatgc ggggtcgaaa gatgccgctg
     2281 aacatctggc acaagagact ggagcgacag cagtatttac agatagtgct gacagagacg
     2341 ctgtcattga tgtcgttcgt aagagcggcg cattggatat cctggtggta aatgcaggta
     2401 ttggcgtctt tggcgatgcc ctggaattaa atgccgacga tattgatcgc cttttcaaaa
     2461 tcaatattca tgctccttat catgcctctg ttgaagccgc ccggcagatg cccgaaggcg
     2521 ggcgcatctt aatcatcggc tccgtgaata gcgatcgtat gcctgttgca ggcatggctg
     2581 cttatgccgc cagcaaatct gccctgcaag gcatggcgcg cgggctggcc cgtgattttg
     2641 gaccgcgtgg gatcaccatt aacgtcgtcc agccagggcc aattgatacc gacgctaatc
     2701 ccgccaacgg gccaatgcgc gatatgttgc atagtttgat ggctatcaaa agacatgggc
     2761 aaccggaaga ggtcgctggt atggtcgcat ggttagcagg gccagaagcc agttttgtta
     2821 ccggcgcgat gcataccatt gatggcgcgt ttggcgcata accgactacg ctcaattaag
     2881 cccagccatt atccatgatg tctgggtttt gtttactcac gtcgtccgct aaaagcggct
     2941 cccggtaaag agaaatcttc tgttcatgtc gtaaatcttg aggataacca aatggtagaa
     3001 agaaccgctg ttttccctgc tggccgacat tcactgtatg ctgagcatcg ttattctgcg
     3061 gctattcgtt ccggcgattt gctgtttgtt tccgggcaag taggaagtcg agaggacgga
     3121 acaccagaac ccgattttca gcaacaagtc agactggcat ttgataattt gcatgcgacc
     3181 ctggctgctg cgggatgcac ttttgacgat atcattgatg ttacgagctt ccataccgat
     3241 ccagaaaacc aatttgaaga catcatgacg gtgaaaaatg aaatatttag cgccccacct
     3301 tatccaaact ggacggcggt gggtgttaca tggctggcag gctttgattt tgaaattaaa
     3361 gtgatagcgc gcatccctga gcagtaagca agagtgttag ccgttcgctt tcacactccg
     3421 ccctataagt cggatgaatg gaataaaatg catatctgat tgcgtgaaag tgaaaaagga
     3481 aaaagcaggg aatgtctgca attattgata ccgaaggaca gttcccctgc agaatcacat
     3541 caaataaaaa tgcatatacc ttgactttta attcaaataa accgtttgcg ctgacaaaat
     3601 attgcatcaa atgcttgcgc cgcttctgac gatgagtata atgccggaca atttgccggg
     3661 aggatgtatg gttcagtgtg ttcgacattt tgtcttaccg cgtctgaaaa aagacgctgg
     3721 cctgccgttt ttcttcccgt tgatcaccca ttcccagccc ctcaatcgag gggctttttt
     3781 ttgcccaggc gtcaggagat aaaagatggc taatccgcta tatcagaaac atatcatttc
     3841 cataaacgac cttagtcgcg atgaccttaa tctggtgctg gcgacagcgg cgaaactgaa
     3901 agcaaacccg caaccagagc tgttgaagca caaagtcatt gccagctgtt tcttcgaagc
     3961 ctctacccgt acccgcctct ctttcgaaac ttccatgcac cgcctgggtg ccagcgtggt
     4021 gggcttctcc gacagcgcca atacatcact gggtaaaaag ggcgaaacgc tggccgatac
     4081 catttcggtt atcagcactt acgttgatgc gatagtgatg cgtcatccgc aggaaggtgc
     4141 ggcgcgcctg gccaccgaat tttctggcaa tgtaccggta ctgaatgccg gtgatggctc
     4201 caaccaacat ccgacgcaaa ccttgctgga cttattcacc attcaggaaa cccaggggcg
     4261 tctggacaat ctccacgtcg caatggttgg tgacctgaaa tatggccgca ccgttcactc
     4321 cctgactcag gcgttagcga agttcgacgg caaccgtttt tacttcatcg cgccggacgc
     4381 gctggcaatg ccgcaataca tccttgatat gctcgatgaa aaagggatcg cctggagtct
     4441 gcacagctct attgaagaag tgatggcgga agtagacatc ctgtacatga cccgcgtgca
     4501 aaaagagcgt ctggacccgt ccgagtacgc caacgtgaaa gcgcagtttg ttcttcgcgc
     4561 cagcgatctc cacaacgcca aagccaatat gaaagtgctg catccgctgc cgcgtgttga
     4621 tgagattgcg acggatgttg ataaaacgcc acacgcctgg tacttccagc aggcaggcaa
     4681 cgggattttc gctcgccagg cgttactggc actggttctg aatcgcgatc tggtactgta
     4741 aggggaaata gagatgacac acgataataa attgcaggtt gaagctatta aacgcggcac
     4801 ggtaattgac catatccccg cccagatcgg ttttaagctg ttgagtctgt tcaagctgac
     4861 cgaaacggat cagcgcatca ccattggtct gaacctgcct tctggcgaga tgggccgcaa
     4921 agatctgatc aaaatcgaaa ataccttttt gagtgaagat caggtagatc aactggcatt
     4981 gtatgcgccg caagccacgg ttaaccgtat cgacaactat gaagtggtgg gtaaatcgcg
     5041 ccccagtctg ccggagcgca tcgacaatgt gctggtctgc ccgaacagca actgtatcag
     5101 ccatgccgaa ccggtttctt ccagctttgc cgtgcgaaaa cgcgccaatg acatcgcgct
     5161 caaatgcaaa tactgtgaaa aagagttttc ccataatgtg gtgctggcca attaattgcg
     5221 gttggtaata aaagtctggc tccctataat gagccagact ttttaccgct gtaataaagg
     5281 agaaatcatg agcaaaacta tcgcgacgga aaatgcaccg gcagctatcg gtccttacgt
     5341 acagggcgtt gatctgggca atatgatcat cacctccggc cagatcccgg taaatccgaa
     5401 aacgggcgaa gtaccggcag acgtcgctgc acaggcacgt cagtcgctgg ataacgtaaa
     5461 agcgatcgtc gaagccgcag gcctgaaagt gggcgacatc gttaaaacca ccgtgtttgt
     5521 gaaagatctg aacgacttcg caaccgttaa tgctacctac gaagccttct tcaccgaaca
     5581 caatgccacc ttcccggcac gttcttgcgt tgaagttgcc cgtctgccga aagacgtaaa
     5641 aattgagatc gaagcgatcg ctgttcgtcg ctaatcttga tggaaatccg ggctatcatg
     5701 cccggattaa atctgatgac aaacgcaaaa ttgcctgatg cgctacgctt atcaggccta
     5761 cgtgattcct gcaattgatt gaatttgtag gccggataag gcatttacgc cgcatccggc
     5821 atgaacaacg ctcactttgt ctgcaatctg aatcggggct atcgtgccca gtttattctt
     5881 tactgccagc cgtaacgacg gctatagaac cctttcacca actgggttaa cgtcatatac
     5941 cctgccagaa tcgcaaccag ccacgggaaa tagcttaacg gcagcgcctg cagctgcaga
     6001 taactggcca gcggtgaaaa cggcaatgcg atcccgacaa tcatcacgat cacggtcatg
     6061 atcattaacg gccacgatgc acagctctga ataaacggca cacggcgggt acggatcata
     6121 tgcacaatca gcgtttgcga cagtaagccc accacaaacc atcccgactg gaacagcgtt
     6181 tgcgtttccg gcgtgttggc atggaatacc caccacatca ggcaaaacgt cagaatatcg
     6241 aagatcgagc tgatcggtcc gaagaagatc ataaagcgcc ccagatccgc cggattccaa
     6301 cgctgcggct tttgaatttg ctcgtcgtcg acgttatcaa acgggatcgc cacctgtgac
     6361 acatcgtaca gcaggttctg aataagcaag tgtaacggca acatcggcag gaagggcaag
     6421 aaagcactcg ccaccagcac gctgaacaca ttaccgaagt tagagctcgc cgtcattttg
     6481 atgtatttca gcatgttggc gaaagtgcga cgtccctcaa taaccccctc ttccagcacc
     6541 atcaggcttt tttccagcag gatgatatca gccgcttcac gggcgatatc taccgcgccg
     6601 tccacagaaa tgccgatatc cgcagcgcgt aaggcgggcg catcattaat accatcgccc
     6661 ataaagccaa ccacatgccc ttcgcgcttc agtaaggtca caatgcgttc tttatgcatc
     6721 ggcgtcagac gagcaaacag cgtggtgcgc tgtgcgagat tagccagttc gtcgtcagat
     6781 agcgtttcaa tatcactacc aatgaccacc tctcccgcgt ccagccccac ttcatggcac
     6841 actttcgctg caactaactc actgtcgcca gtaaggattt ttacggtaat tccactcgct
     6901 tttaatgcct tcagtgccgg agcagttgtc tcttttggcg gatcaaggaa agcaatatat
     6961 ccttcgagga tcaggtcgga ttcatccgcc cgctggtaat ctccttcacg cgctggcagg
     7021 tatttcgtcg ccaccgcaac cacgcgcagc ccctgacgat tcagcgtatc agtaacccgc
     7081 ttaatcttac gcagcatgat gtcatcgagc ggcacaatct cgccattgtg acgcacctgc
     7141 gaacacacat tgaggatttc ctgcaatgca cctttgcaaa ccagctgatg gtgttcggta
     7201 ttttctgcca ctaccaccga catccgacga cgctcgaaat caaacggaat ctcatcaatt
     7261 ttttgccaac ggctggccag cgagtgcgct gactcttcat ccgtaccttc gagcaccgct
     7321 gtatcgagca ggtttttaag tccggtctga taatgactgt tcaaccacgc gctatgcagc
     7381 acgcgttcgc tggttttacc ggagatatcg gtatgattct ccagcacaat tttgtcctgt
     7441 gtcagggtgc cggttttatc agtgcacaga atatccattg cgccaaagtt ctgaatagca
     7501 tccagatgtt tgacgatcac tttctgtttc gacagcttta ctgcgccgcg cgccagcgtc
     7561 gaggtaacaa tcatcggcaa catttccggc gttaggccta ccgcgaccga aagcgcaaac
     7621 agcgccgctt cccaccagtc gcctttggtg tagccattga ttaacagcac caccggtgcc
     7681 atcaccagca taaagcgaat cagcagcata ctgacgcggc tgatcccttg ctgaaaggca
     7741 ttcggctcgc tttcctgctc actaacacgc cccgccagtt gaccaaacca ggtattggca
     7801 cctgtagcaa tcaccattgc ttgtgccgtg ccgctcacca cggtggtgcc cataaaacac
     7861 agggtgtcgc actccagcgg attgctgtgc tccggctggc gagtggttgc ggctttttct
     7921 acgggcagag actcaccggt taacgacgcc tgagcgacga acagatcccg cgcctgcaag
     7981 atacgtaaat ctgccgggat catatctccc gccgccagtt ttataatatc gccgggcacc
     8041 agctggtcga tcgggatctc cagccagcca ttttcgcctt tgtcgttaat tacgcgcagc
     8101 accgtcgcag tattgctgac catcgctttc agggcatctg ccgctttagt ggaacgtgct
     8161 tcctgaataa agttcagcaa cgtagaaatg gcgaccatta gcgcgataac gcccgcggca
     8221 aataaatctt ccgtggcgta agaaatagcg ccgagaatgg tgagtaaaat attaaagggg
     8281 ttgcgatagc agacccataa atgtacccac cacggcgacg gttgttgtgc gggtaattta
     8341 ttttcaccat gttgttcgcg ggcagattcc acttccgcct gatttaaccc ttccggatgg
     8401 gtgtcgaacg ttttccacaa ttcttcttcg ggcatcaccg ccattttcag gcaatgcgca
     8461 cttaaggacg gcgggaccac cgtattcact gtctgctgcg cgccaggcaa tggatcacga
     8521 tgaaccagac gggaaggtaa atggcgaatg agccgggtaa aaatttcttt aaacataagg
     8581 agtccctccg cactgtctga aacagtacag aaatgtcttc aggcgtggcg aagccttacc
     8641 tgaaggtaat aaagctgagc agggacgtta aaacgtcacg gccttacgca tccggtaacg
     8701 ccgtgaaaag acgggcttac cgaaaaagtt ttaatctccg tcgagggaga ggcgtgggat
     8761 caggttccat ataacctccg gtaagtgaaa aaagcgccgc aaataataag gagaatccaa
     8821 taatattcgt agcatttatg gcgatataat acctgctggc aactaaacca acgataaacc
     8881 agactttacc cattgctgaa tgcacgggta aagttagcct caaataatta aacaacacgt
     8941 tacgggacaa caggatgcaa aatcggctga ccatcaaaga catcgcgcgc ttaagcggcg
     9001 tggggaaatc tacggtttcc cgggtgctga ataacgaaag cggcgtgagc cagcgcacgc
     9061 gcgagcgcgt ggaagcagtg atgaatcagc atggattttc cccttcccgc tctgcgcgcg
     9121 ctatgcgtgg gcaaagcgat aaagtggtcg ccatcattgt tacccgcctg gattcgttgt
     9181 cagaaaatct cgccgttcaa accatgctgc cagcgttcta tgaacaaggt tacgacccaa
     9241 tcatgatgga aagtcagttt tccccgcaat tagttgccga acatttgggg atcctaaaac
     9301 ggcgtaatat cgacggcgta gtgctgttcg gttttaccgg cataacagaa gaaatgttag
     9361 cccactggca gtcatcgctg gttctgctgg cgcgtgacgc aaaaggcttt gcttcggtct
     9421 gttatgacga cgaaggggca atcaagatcc tgatgcaacg gctctatgac caggggcatc
     9481 gtaatatcag ttatctcggc gtgccgcaca gtgacgtgac gaccggtaag cgacgtcacg
     9541 aagcctacct ggcgttctgc aaagcgcata aactgcatcc cgttgccgct ctgccagggc
     9601 ttgctatgaa gcaaggctat gagaacgtag caaaagtgat tacgcctgaa actaccgcct
     9661 tactgtgcgc aaccgacacg ctggcacttg gcgcaagtaa atacctgcaa gagcaacgca
     9721 tcgacacctt gcaactggcg agcgtcggta atacgccgtt aatgaaattc cttcatccgg
     9781 agatcgtcac cgtagatcct ggttacgccg aagctggacg ccaggcggcc tgccaattga
     9841 tcgcacaggt aaccgggcgc agcgaaccgc aacaaatcat catccccgcc accctgtcct
     9901 gatcgtttcc tgaacgataa attgtgatct tcgctgcgtt tcgggaacgt tcccgttttt
     9961 aaatttttcc gcgcaatata ttctgcagcc aaccaaaaat gtcatctgcc atggggcttt
    10021 atgatgagca aaataaacca aacggatatc gatcggttga ttgaactggt cggcgggcgc
    10081 ggcaatattg cgacggtgag ccactgtatt actcgcctgc gctttgtcct caaccaaccg
    10141 gccaatgcca gaccgaaaga aattgagcaa ctccccatgg tgaaaggctg tttcaccaat
    10201 gccgggcaat ttcaggtggt gattggcacc aatgtgggtg attactatca agcactgatt
    10261 gcgtcaaccg gacaggcgca ggttgataaa gagcaggtaa aaaaagccgc ccggcagaat
    10321 atgaaatggc atgagcagtt gatctctcat ttcgcggaga tcttcttccc gttgctgccc
    10381 gcgttgatta gcggcggttt gatcctcggt tttcgcaatg tgatcggcga tttgcccatg
    10441 agcaacggtc aaacgctggc gcaaatgtac ccttccctgc aaacgatcta cgattttctg
    10501 tggttgatcg gtgaagcgat cttcttctac ctgccggtcg ggatttgctg gtcagcggtg
    10561 aaaaaaatgg gcggcacgcc gatccttggt atcgtacttg gcgtaacgct ggtttctcca
    10621 cagctgatga acgcttatct gctcgggcag cagctgccgg aagtgtggga ctttggcatg
    10681 ttcagcatcg ccaaagtagg ctatcaggcg caggtgatcc cggcactgtt agccgggctg
    10741 gcgctgggcg ttattgaaac tcgccttaaa cgcatcgtgc cggattacct ctatctggtg
    10801 gtggtgcccg tctgttcgct gatcctcgcg gtgttcctcg cccatgcgct gattggtccg
    10861 tttggacgca tgattggcga tggcgttgcc tttgcggtac gtcacctgat gaccggcagc
    10921 tttgcaccta ttggcgcagc attgtttggc ttcctgtacg ccccgctggt gatcaccggt
    10981 gtacaccaga ccacgcttgc tattgatttg cagatgattc aaagcatggg tggtacgcca
    11041 gtgtggccgc tgattgcgct gtcgaatatc gctcagggct ccgccgtgat aggcattatc
    11101 atttccagcc gcaagcacaa tgaacgcgag atctccgtgc ctgccgctat ctccgcctgg
    11161 cttggggtca ctgagcctgc aatgtacggc atcaacctga aatatcgctt cccgatgctg
    11221 tacgcgatga ttggttctgg tctggcagga ttgctatgcg gcctgaacgg cgttatggcg
    11281 aatggcatcg gcgtaggcgg cctgccggga attctctcga ttcaaccgag ctactggcag
    11341 gtgtttgcgc tggcaatggc tatcgccatc atcatcccga ttgtactcac ctcgtttatc
    11401 tatcagcgga aataccgcct gggcacgctg gacattgttt aattttcttc ggggcgcaat
    11461 tgcgccccct cgcattcgca ggaataacgt aatgactaat cttccccact ggtggcaaaa
    11521 cggcgttatc taccagattt atccaaagag ttttcaggac accacgggta gcggtaccgg
    11581 cgatttacgt ggcgttatcc aacgcctgga ctatctgcat aaactgggcg ttgatgccat
    11641 ctggctaacc cccttttatg tctctcccca ggtcgataac ggttacgacg tagcgaacta
    11701 tacggcgatt gatcccacct acggcacgct ggacgatttt gacgaactgg tgacgcaggc
    11761 aaaatcgcgc gggattcgta tcattctcga tatggtgttt aaccatacct ctacccaaca
    11821 tgcctggttt cgcgaggcgc tgaacaaaga aagcccttac cgccagtttt atatctggcg
    11881 cgatggcgaa ccagaaacgc caccgaataa ctggcgttca aaatttggcg gtagtgcgtg
    11941 gcgctggcat gcggaaagcg aacagtacta tttgcatctc tttgcaccag aacaggcgga
    12001 tctcaactgg gagaatccag cggtacgcgc agagctgaaa aaagtctgtg aattctgggc
    12061 cgatcgtggg gtcgatgggt tgcgcctgga tgtggtgaat ctgatctcca aagacccgcg
    12121 tttccctgaa gacctggatg gcgacgggcg tcgcttctac accgacgggc cacgagcaca
    12181 cgagtttttg cacgagatga accgcgatgt gtttacgcca cgcgggttaa tgaccgtagg
    12241 tgaaatgtcc tccaccagcc ttgagcattg ccagcgatac gcggcactgg caggcagtga
    12301 attatcgatg acctttaatt ttcatcacct gaaggtcgat tatcccggtg gtgaaaaatg
    12361 gacgctggct aaacctgact ttgtggcgtt gaaaacattg ttccgccact ggcaacaagg
    12421 aatgcacaac gtagcatgga atgccttgtt ctggtgtaac cacgatcagc cgcgcattgt
    12481 ttctcgcttt ggtgatgaag gtgaataccg cgtgcctgcg gcaaaaatgc tagcgatggt
    12541 gctgcatggc atgcagggaa cgccgtatat ctaccagggc gaagagattg gcatgaccaa
    12601 cccgcatttc acgcgcatta ctgactatcg cgacgtggag agcctcaata tgtttgccga
    12661 gctgcgcaac gatgggcgtg atgccgacga gttattggca atcctcgcca gtaaatcccg
    12721 tgacaacagc cgcacgccca tgcaatggag caacggcgat aatgccgggt ttacggctgg
    12781 cgaaccgtgg attggcctgg gcgataacta tcaacaaatc aacgtagaag ccgcgctggc
    12841 cgatgattcc tcggtgtttt acacctacca aaagttaatc gcactgcgta agcaggaagc
    12901 catcctgaca tggggcaatt accaggatct gctgccaaac agccctgtat tgtggtgcta
    12961 tcgccgtgaa tggaaggggc aaaccttgct ggtcattgcc aaccttagcc gtgagatcca
    13021 accctggcag ccagggcaaa tgcgcggcaa ctggcagctt gtgatgcata actacgaaga
    13081 agcctcacca caaccctgtg ccatgaattt acggcctttt gaggctgtct ggtggttaca
    13141 gaagtaaatc ttccctaagc cccggtaatg ccggtcattc cggggttttg tctgtcagca
    13201 tgttgttttt gttgattttt caaccagcaa attcattaaa aaatttacat aacgctgtag
    13261 cgcccgtcat ccgtacgctc tgctttttac tttgagctac atcaaaaaaa gttcaaacat
    13321 ccttgatgca aagcactata tatagacttt aaaatgcgcc ccaacccaat atgttgtatt
    13381 aatcgactat aattgctact acagctcccc acgaaaaagg tgcggcgttg tggataagcg
    13441 gatggcgatt gcggaaagca ccggaaaacg aaacgaaaaa accggaaaac gcctttccca
    13501 atttctgtgg ataacctgtt cttaaaaata tggagcgatc atgacaccgc atgtgatgaa
    13561 acgagacggc tgcaaagtgc cgtttaaatc agagcgcatc aaagaagcga ttctgcgtgc
    13621 agctaaagca gcggaagtcg atgatgccga ttattgcgcc actgttgccg cggttgtcag
    13681 cgagcagatg cagggccgca accaggtgga tatcaatgag atccagaccg cagttgaaaa
    13741 ccagctgatg tcgggtccat acaaacaact ggctcgtgct tacatcgagt accgtcacga
    13801 tcgcgacatt gaacgtgaaa aacgcggtcg cctgaaccag gagatccgtg gtctggtcga
    13861 gcagaccaac gcctcgttac tcaacgaaaa cgccaacaaa gacagcaagg tgattccaac
    13921 ccagcgcgac ctgctggccg ggatcgtggc taaacactat gcacgtcagc acctgctgcc
    13981 gcgtgacgtg gtgcaggcac atgagcgtgg cgatattcac tatcacgatc tcgattactc
    14041 accgtttttc ccgatgttca actgcatgtt gatcgacctg aaaggcatgc tgacccaggg
    14101 ctttaaaatg gggaacgccg agattgaacc gccgaagtcg atctcaacgg caaccgcggt
    14161 aactgcgcag attattgctc aggttgccag ccatatttat ggcggcacca ccattaaccg
    14221 tatcgatgaa gtgctggcac cgtttgtcac cgccagctac aacaaacatc gcaagaccgc
    14281 agaagagtgg agcatcccgg acgcagaagg ctacgctaac tctcgtacca ttaaagagtg
    14341 ctacgatgcc ttccagtcgc tggagtacga agtaaacacc ctgcataccg ccaacggtca
    14401 aacgccgttt gtaacttttg gttttggtct gggcaccagc tgggaatcgc gcctgattca
    14461 ggaatctatc ctgcgtaacc gtatcgcagg tctcggtaaa aaccgtaaaa ctgcggtgtt
    14521 cccgaaactg gtgtttgcga ttcgcgatgg tctgaaccat aaaaaaggcg atccgaacta
    14581 cgacatcaaa cagctggcgc tggagtgcgc aagcaagcgc atgtatccgg atatcctgaa
    14641 ctacgatcag gtagtgaaag tcaccggttc gtttaaaacc ccgatgggct gccgcagctt
    14701 cctcggcgtg tgggaaaatg aaaacggcga gcagatccac gatggtcgta acaacctcgg
    14761 cgtgatcagc ctgaacctgc cgcgtattgc tctggaagca aaaggcgatg aagccacctt
    14821 ctggaagctg ctggatgaac gtctggtgct ggcacgtaag gcgctgatga cccgtatcgc
    14881 tcgtctcgaa ggcgtgaaag cgcgcgtggc cccgatcctc tatatggaag gtgcttgtgg
    14941 cgtgcgtctc aatgctgacg atgatgtttc tgaaatcttc aaaaacggtc gtgcgtctat
    15001 ttcgctgggt tacatcggca tccacgaaac cattaacgcg ctgttcggcg gcgagcatgt
    15061 ttacgacaac gagcagcttc gcgcgaaagg tatcgccatt gttgaacgtc tgcgtcaggc
    15121 agtggatcag tggaaagaag aaacgggtta tggtttcagt ctctacagca cgccgagtga
    15181 aaacctgtgc gaccgcttct gccgtctcga tactgctgag tttggcgtgg tgccgggcgt
    15241 gaccgataaa ggttactaca ccaacagttt ccacctcgat gtggagaaga aggtgaaccc
    15301 gtacgacaag atcgactttg aagcgcctta cccgccgctg gcgaacggtg gtttcatttg
    15361 ctacggcgag tatccaaaca ttcagcacaa cctgaaggcg ctggaagatg tctgggatta
    15421 cagctatcag catgtaccgt attacggcac caatacaccg attgatgagt gctacgagtg
    15481 tggctttacc ggtgagttcg agtgcaccag caaaggcttc acttgcccga aatgtggtaa
    15541 ccatgacgcc tcccgtgtgt cggtaactcg ccgcgtgtgc ggatatttag gtagcccgga
    15601 tgcacgtcca tttaacgccg gtaagcagga agaagttaag cgccgcgtta aacatttggg
    15661 aaatgggcag ataggttaat cttcactcta cgttaagcaa atgccggatg cggcgtaaac
    15721 gccttatccg gcctacattt ggcaactgct ccaggcctga taagacgcga cagcgtcgca
    15781 tcaggcattg attaccggat gcagcctaca cgcggactga taagccaggc gaaataatga
    15841 attatcatca gtactatcct gtcgacatcg tcaacggccc cggcactcgc tgcaccctgt
    15901 ttgtctccgg gtgtgttcat gaatgccccg gttgctataa caaaagcaca tggcgggtaa
    15961 attctggtca gccatttacc aaagcaatgg aagaccagat cattaacgat ctgaatgaca
    16021 ctcgtatcaa acgccagggg atttccctct ccggcggcga tccgctgcat ccgcaaaacg
    16081 tgccggatat tctgaaactg gtaaaacgca tccgcgccga gtgtccggat aaagacatct
    16141 gggtgtggac aggctataaa ctcgacgatc tcaacgctgc gcaaatgcag gttgttgatt
    16201 tgattaacgt actggtcgac ggcaaatttg tgcaggattt aaaagaccct tccctgatct
    16261 ggcgcggcag cagcaatcag gtggtgcatc atttgcgatg ataagttccc tgttacctga
    16321 gtgcaggcaa cagggaaatg aggaattaac gatacttctg gtgataggcg ttgcgggtcg
    16381 ttttcagttg ctctgcggca gcctgcgctt cttttacttt accttcatta gccagcttca
    16441 gcgcgtcgtc aatctggcca accagaatgt cgaaaccgtg gcggaagtct ttcatttccg
    16501 ggctgtctgg cgattttcct tccagcttcg gcggcgttgc tttttgcgca tccagcgctg
    16561 cggcgcgcat cttcgttaac gcgtctttga cttgcgccgc gttatcggct ttttcgacca
    16621 cttttaaatt gtcgttgagg gtttccatat tgtcttcaag atcagcggca aacgacgccg
    16681 aactgaatac caacgaggag actgcaagaa tagctaacag gcttttacgc attgctcact
    16741 tcctttttta ttatgaagat ttggcgcggc aggtcgcgcc atttttttac tgcccggcga
    16801 ttttcatctc cggcaacagc acagaaccac actgtatatt actgcgtgtt tcaatatcgt
    16861 taccgacggt gacaatattg cgccacatat cttttaaatt acctgcgatg gtgatttcgc
    16921 taaccggata ctgaatttcg ccgttttcta cccagaagcc cgccgcacca cgggaataat
    16981 caccggtaat tgcactcacg ccctggccca tcagctccgt caccaccagc ccggtgccca
    17041 tctctttgag catttgttcg aagcttagcc cttgtccggc aatccgccag ttgtgaatac
    17101 cgcccgcatg tccggtgctt ttcagcccca gttttcgcgc cgaatagctg gtcagcagcc
    17161 actgagtcag gatgccatct ttaataatat cgcgacgctc ggtgcgcaca ccttcgctgt
    17221 cgaatggcgt cgacgccagc cctttcagca gatgcggatg ctcttcaatg gtcagccagt
    17281 ccggcagaat ttgtttaccc agcgaatcca gcagaaaggt agatttacgg taaaccgagc
    17341 cacccgctat cgcccccacc agatggccaa aaagcccggt tgccacttca ttggcaaaaa
    17401 tgaccggcgc tttcatggtg gagagtttac gcggtgacag gcgcgataaa gtacggcgag
    17461 cacagtcggc cccaacccac tctggcgttt gcagatcgct catcgcacga ccaatggtgt
    17521 aggcgtaatc acgctccata tcgccatttt cttcggcaat tacacagctg gagagcgaat
    17581 gacgcgttga gcagtaaccc tgcaacatgc cgtggctgtt gccaaaaact ttgacaccgt
    17641 agtggctgtt aaagctgcca ccttcggtat tggtgatgcg tttgtccgcc tgcaatgccg
    17701 cctgttctgc gcgggccgcc agttcaatgg cttcatccgg ggaaacttcc gcagggtgga
    17761 acaagtcgag atctggtgcg tcaaaggcca gcagctcttt gtctgccacg ccggcacagg
    17821 gatctggcga ggtataacgg gcaatatcca gcgccgcctg tacagtacgg gcaatggcct
    17881 gcgggcttaa atcggtggat gatgcgctac ctttgcggtt ctggtgataa acagtgatcc
    17941 ccagcgcgcc atcgctattg aattcaacat tctccacttc accataacgc gtgcttacgc
    18001 taatgccggt ggtcttgctg acggcaactt ccgcaccgtc cgatttgcct gaggccaact
    18061 ccagcgcagt ggaaactgct tcttccagaa tcttgcgctg cgcttcaact tgagagatta
    18121 ctttcattgc aagtgccata atgtagagag tttctctgaa gtctaacaga gaaccgtttt
    18181 tcagtgcgca tcttaactgg taacattagc ctcttttttt aaggagcctg agatgactaa
    18241 gcagcccgaa gactggctcg acgacgttcc cggtgatgac atcgaagacg aagacgatga
    18301 aattatctgg gtcagtaaaa gtgaaattaa acgtgatgcc gaggagctaa aacgccttgg
    18361 cgcggaaatt gttgatctgg ggaaaaacgc gctggataag atcccgttag atgcggatct
    18421 gcgcgcggct attgagctcg cccagcgtat taagatggaa ggtcgccgcc gccagttgca
    18481 gctcatcggt aagatgctgc gccagcgcga tgtagaaccg atccgtcagg cgctggataa
    18541 gctgaaaaac cgtcacaacc agcaggtggt gctgttccat aaactggaaa acctgcgcga
    18601 tcgtctgatc gatcaaggtg atgacgccat cgctgaggta ttaaatctgt ggcccgatgc
    18661 cgatcgtcag cagctgcgta ctctgatccg caacgcgaag aaagagaaag aagggaataa
    18721 gccgccgaaa tccgcacgcc agattttcca gtatctgcgc gaactggcgg agaatgaagg
    18781 gtaattttcg ttgttgatgt gagtatggtt tgccggatgc ggtgcacctg taggcctgat
    18841 aagacgcatc aagcgtcgca tcaggcacta tgctcaaatg ccggatgcgg cgtgaacgcc
    18901 ttatccggcc tacgcacact atatcaggct gaggccgaat tactgcgcag cttccgcctt
    18961 cttcgccaga ccatccagca gtttctgatg gatcccacca aaaccgccgt tgctcatcac
    19021 cagaatatgg tcgccaggct gagcggtttt caccaccata tctgccagcg tatccacatc
    19081 gccactccag tgtgcaggct gaacgcaggc ttctgccact tctgccacct gccacggaat
    19141 atgcgccggt tgcagcagga agacttcatc ggcacgacct aatgaaggtg ccagatcgtc
    19201 tttgcagatc cccattttca tggtattcga gcgcggttcc agcacagcaa taatgcgcgc
    19261 cgtaccacca actttgccac gcagcgccgc cagcgttgcc agaatcgccg tcgggtgatg
    19321 ggcaaaatcg tcatataccg tgacgccatt cgcttcacca cgcaactcca gacggcgacg
    19381 agcattaata aacgaaccca gcgcgttagc ggcatctgcc ggcgctacac caacatggcg
    19441 agccgctgca atcgccatca ggccattgtg catattatgt tcgcctacca gcgaccattt
    19501 cacttcgccc actttttcgc catccagcaa aacttcccat tcggaagcat cggtggtcag
    19561 ctttttcgcc tgccagtgac cctgctcacc caccagctcc tgctcgctcc agcagcccat
    19621 cgccatggtc tgtttcaggt tgatgtcatt ttccggccag ataatacggc cctgccccgg
    19681 aacgatacgc accagatggt ggaactgttt ctggatcgct ttcaggtcgt caaagatatc
    19741 ggcgtgatcg aactcaaggt tgttgaggat cagcgtacgc gggcagtaat ggacaaattt
    19801 agagcgtttg tcgaagaagg cgcagtcgta ctcatccgct tcgataacaa agaagtcgct
    19861 ttcgcccaga cgcgccgaaa cctcaaagtt ccccggcaca ccgccgatca caaatcccgg
    19921 tttgtaaccg cactgttcca gaatccaggt cgccattccc gcggtggtag ttttgccgtg
    19981 tgtaccggca acggccagca cccagcggtc gcgcagcaca aaatcgtgca gccactgtgg
    20041 acctgacata taagggatgt ttttttccag taccgcttcc acacacggat ttccacgggt
    20101 catggcgttg ccaataatca ccagatccgg ctgcggatcg agctggctgg catcgtaacc
    20161 ctgaatcagc tcaatgcctt gcttctcaag taaggtgctc atcggcggat acacattggc
    20221 gtccgaaccc gttacttcat ggcctaactg gcgcgccagc atcgccagac cgcccataaa
    20281 tgtgccacaa attcctaaaa tatgaatgcg catacgtcac tatccttttt taatctgccg
    20341 ctcattttac gcatatgtcg ggcaagtgag aaacgcattt caggataatc cgcaatttgc
    20401 tggcgcgatt cacctgagcg caacattgag attatttgtt aagattgttg cggtcgcttt
    20461 actccataaa cattgcaggg aaagttttat gaaaacgtta ggtgaattta ttgtcgaaaa
    20521 gcagcacgag ttttctcatg ctaccggtga gctcactgct ttgctgtcgg caataaaact
    20581 gggcgccaag attatccatc gcgatatcaa caaagcagga ctggttgata tcctgggtgc
    20641 cagcggtgct gagaacgtgc agggcgaggt tcagcagaaa ctcgacttgt tcgctaatga
    20701 aaaactgaaa gccgcactga aagcacgcga tatcgttgcg ggcattgcct ctgaagaaga
    20761 agatgagatt gttgtctttg aaggctgtga acatgcaaaa tacgtggtgc tgatggaccc
    20821 actggatggc tcgtccaaca tcgatgttaa cgtctctgtc ggtaccattt tctccatcta
    20881 ccgccgagtt acgcccgtcg gcacgccggt aacggaagaa gatttcctcc agcctggtaa
    20941 caaacaagtt gcggcaggtt acgtggtata cggctcctct accatgctgg tttacaccac
    21001 cggatgcggt gttcacgcct ttacttacga tccttcgctg ggcgttttct gtctgtgcca
    21061 ggaacggatg cgcttcccgg agaaaggcaa aacctactcc atcaacgaag gaaactacat
    21121 taagtttccg aacggggtga agaagtacat taaattctgc caggaagaag ataaatccac
    21181 caaccgcccg tatacctcac gttatatcgg ttcactggtc gcggatttcc accgtaacct
    21241 gctgaaaggc ggtatttatc tctacccaag caccgccagc cacccggacg gcaaactgcg
    21301 tttgctgtat gagtgcaacc cgatggcatt cctggcggaa caagcgggcg gtaaagcgag
    21361 cgatggcaaa gagcgtattc tggatatcat cccggaaacc ctgcaccagc gccgttcatt
    21421 ctttgtcggc aacgaccata tggttgaaga tgtcgaacgc tttatccgtg agttcccgga
    21481 cgcgtaatct cctgcgcctc tccacacgga gaggcgtttt tatcgctgcg caatgttgac
    21541 tcttgtcact ggcgaactct gacgattctc ccacagcacc gttaacccac gctgtaatgc
    21601 tataaaaata aacaacaaaa taccgatggc gattttcgtc caccaggaac tcagcgtgcc
    21661 gtcaaagttg atgtaagtct ggatcagtcc ctgaattgcc acgccaaaaa gcgtcccaag
    21721 caccgtcccg acgccaccac ttaacaacgt accgccaatc accaccgacg cgatggcgtc
    21781 cagttccaca cctacgcccg ccagtgcata tccggcctgg gtataaatcg agaagacaat
    21841 ccccgccagt gttgccagtc cggtggagag catataaatg cgaatagtgg tgctgcgagt
    21901 agaaatcccc atcaggttcg ccgacgtcgc gttgccgcca atagcgtaca cctgattgcc
    21961 aaaacgggta cgatgcgcaa ggaaaatacc gataaccacc accgccagca tcaacagccc
    22021 catcgcacta aggcgaccgc cgccggggat tttccacgca aggcttgaga gcgtgtcata
    22081 aatgggatgg tttatcggaa tcgactcttc cgaaacgaga tagctgacgc cgcgcaaaaa
    22141 gaacatcccc gcaagcgtaa tgataaatgc cgggatcttc agggcgtcga tcagaagccc
    22201 cataaatgcg ccgaaggcac agcccatcac cagcactagc ggaaacgcca gcagcggcga
    22261 gaggccgaaa tcgccaacca cttttgccag aaacacgcca gtaaaggcga tcaccgaacc
    22321 gacggagaga tcgataccgc cagagaggat cacaaaggtc atgccaacgg cgattatccc
    22381 aagaaaggcg ttatctgtca ggatattgca gatcactctt gtggaagcaa aaccgggaaa
    22441 ctgcgtcagg cagtagaaat agcccagcac aaagacgccg atggtgatca tcagtggcaa
    22501 attacgtttt atcatggcta cgtactcctt taatcagact gataaagcgt tgcgactgaa
    22561 caatcagcac acaaagcacc accaccgctt ttacgacctg gttcatctcc ggcggaaagc
    22621 cagaaagtaa aattccggtg ttcatcccct gaataatcag cgcccccacg actgagagca
    22681 gcaggttaaa gcgcccgccc atcagcgatc cgccgccaat caccaccgca agaatggcgt
    22741 ccagctccag ccataacccg gcgttattgg catcggcacc gcgaatatcc gccgccacga
    22801 taatgcccgc aatcgccgca cacagcccgc tcaacacgta ggtgagcatg acgatgatcc
    22861 gcgtgtttac cccggcattt tttgccgccc gaatgttgat accaacggct tcgataaaca
    22921 tccccagcgc cgttttgcgg gtcaacagcc agaacaggag aagcgtcatc accgcgataa
    22981 tgaccggcgt tggcaggaac aacagcgatc cgctgccaaa ccatgagaga tccggcgagt
    23041 taaacgtgac gatctgcccg gcggtgatca gttgcgccac gccgcgcccg gcgaccatca
    23101 ggatcagggt ggcgacaaac ggctgaattt tgaggatcgc taccagtatg ccgttccaca
    23161 atcccgccag gatgccggtg cccagggcgc ttaacaaaac aatcggcagg ctgaatcccg
    23221 cgaccgtcat cgcagccgtt gtggctccgg cgatagccat caccgcccct acggagagat
    23281 caatcccacc ggtggcgatc accagcgtca taccaatcgc cagtaacgca acgggagctg
    23341 cacggttaag aatgtcgata gggctaccga acaaacgccc atcctgaagc accacctgcc
    23401 agaaatgcgg ggctaccagg ctatcgacca gcagcaccag caatagcgcc gccagctgcg
    23461 gcattcccgt tggccagcga aagcgccttt tcggcggcgt agtgtccggg agagattgag
    23521 gcatcacact gttctcctta cgccgcaatg gcgttcatga tcgccggaac ggaaagctct
    23581 gccagcggga tctccgccac ctgtttgcga tcgcgcatga taatcacccg atcggcatag
    23641 cccaccagct cttccagttc ggaggagatc accaacagcg ccagaccgtc agcacacagc
    23701 gtttcaatca ggcggatgat ctcggcgtgg gcaccaacat caatgccgcg ggttggctcg
    23761 tcgaggatca gaaattgcgg tcgggtcagt agccaacgtg aaagcaacac tttttgctga
    23821 ttgccgccag agagaaattc aatcggttgt tcagttgaag gtgtgcgaat gccaagctgg
    23881 cggataaagc gttcggcaat ctcttgctgc tctttgcggg aaatgggtcg tagccagccg
    23941 cgctgggcct ggagagcgag gatgatattt tcccgtaccg aggcggcggc gatgatgcca
    24001 tcggttttcc tgtcttccgg gcagaagccg atgcccagta ccgaagcctg atgtggcgat
    24061 cgcaggtttt gcggtttgcc tttgatcaac gccgtgccgc tgtcagcagg tttgataccg
    24121 aagatcactt cggcggtttc ggtacgtccg gatcccagca agcctgccag gccgacgatc
    24181 tcgccggggc gtacttcgag atcaaacggt gcgatcgttc cttttttgcc gtaatttttg
    24241 aacgcggcaa cgggtttgtc gctcaacaat gttcgcccgg cacgctgtag cgcgtgggta
    24301 tccagctcgc gccccagcat catttttacc agttcgatct gcggtagctc gcgcgtttcc
    24361 cgacagccta cgaaactgcc gttgcgtaag acggtgatcc gatcgctgac ctgatagacc
    24421 tgatcgagaa agtgagtgac aaagatcagg ctgacgccgc gatcgcgcaa ctgacgcatc
    24481 aggccaaaca gtaactctac ttcctgggtg tcgaggctgg cggtgggttc atcgaggatc
    24541 agcactttgg cggagagatc gatagcccgg caaatggcga cgatttgctg catcgccacc
    24601 gaaaaacggt taagcggttc acgcacgtcg agggagaaac cgtaagatgt catcagttcg
    24661 gtggcacgct tttccatctc tttgcggcgt agaaagccga aacgtttggg ttcgcgacct
    24721 atgaatagat tatcagcgac cgacatattg ggtagcaggt tgacttcctg ataaacggtt
    24781 ccgatgccga gttgttgtgc atgggcggta tttttcggtg agatagcctg gccttccagc
    24841 cagatggtgc cgcgatcggc gtggtataca ccggttaatg ctttgattag cgtcgatttt
    24901 cccgccccgt tttcaccgag cagcgccatg atttcgccac ggcgcaggct gaaatcaacg
    24961 ttgtctaacg ctttgacgcc ggggaaaaat ttacttaatc cttcggtgcg gaggatttcc
    25021 tggtgttggt cggtcgtcat ggtttccccc ttagccacgc tctaaaagtc tgggaataga
    25081 tcgtgcctga tgttaagagc tgcgccgttt gtccccctca ccctaaccct ctccccgaag
    25141 gggcgagggg acagattgtg cacggtgtta agtccggtgt tgcaccactg ccggatgcgg
    25201 cgtgaacgcc ttatccggcc tacacagagc accgaactcg taggcatgat aagacgcggt
    25261 aagcgtcgca tcaggcttca gcgcaccacc gccggatgcg gcgcgagcgc cttatccggc
    25321 ctacgaatcg gcatcaggca ttgataccct caatacccca tatttttctt cttctctaac
    25381 tcttcttttg cggtatcagg cagataaagg gtggatttgg tcagcgttag cttttcaggc
    25441 atggtgccgt cttttttgta tttctccagc gcgtcgaagg cgggacctgc catattcggc
    25501 gtcagttcaa cactggcgtt cgcttcgcca tcaatcatcg ctttgtagat atccggtacg
    25561 ccatcaatgg aacccgtgag gatatcttta cccggcttca ggcccgcttc tttaattgcc
    25621 tgaattgcac caatcaccat gtcatcgtta tgggcgtaaa ccatgcagat gtttttgccg
    25681 ttgttttccg ctttgataaa gctctccatg acttctttgc ctttactgcg ggtgaagtca
    25741 cctgactgcg agcggataat tttgatattt ggcgcattct taatggcttc ggcaaagcct
    25801 ttcttacggt caatggcgac gctggcccca acggtgccct gcagctccac cacgttgcat
    25861 ggtttgccat tcacttcttt taccagccag tcaccaatca acttgccttc gaggatgttg
    25921 tcggcggtga cagtggtcat atagagagat ttgtctttca catcgatgga acggtcaagc
    25981 aagaagaccg ggatttcggc atctttcgcc tcttttaata ccggctccca acccgtcgct
    26041 accactggag cgataaagat cgcatccacc ccttgtgcaa cgaaggaacg taccgcttta
    26101 atctggtttt cctgcttttg ttgaccatcg gcaattttca acgtaattcc gcgtttttcg
    26161 gcctcacttt tcgccacatt ggtttctgcg gcacgccagc cggattccga tccgacctgc
    26221 gaaaatccta cggttaatgg agcggccaac gccatagacg acatggctgc cgagactgca
    26281 gagactacaa gtaagcgttt ccacataggg ttgtcctcgt cggggtaatt attattggtg
    26341 aaaagatgtt cgcggaaaaa ctatagacaa ttcgttatgt aacggattgc gttacatcac
    26401 acttcataaa agtaaataaa acgttaatca caagtttgta atcgctttca tctcactatg
    26461 aaaaatgcgg ctacggttat ggattttcct gctctgtata ccgtcttaaa actggcgaaa
    26521 aaggaaaatg aagacgaaaa caagcgaaga cattcggcgc gagttggcta taatactcgg
    26581 cacttgtttg ccacatattt ttaaaggaaa cagacatgag cttactcaac gtccctgcgg
    26641 gtaaagatct gccggaagac atctacgttg ttattgagat cccggctaac gcagatccga
    26701 tcaaatacga aatcgacaaa gagagcggcg cactgttcgt tgaccgcttc atgtccaccg
    26761 cgatgttcta tccgtgcaac tacggctata tcaaccacac tctgtctctg gacggtgacc
    26821 cggttgacgt actggtcccg actccgtacc cgctgcagcc gggttctgtg atccgttgcc
    26881 gtccggttgg cgttctgaaa atgaccgacg aagccggtga agatgcgaaa ctgattgctg
    26941 ttccgcacac caagctgagc aaagaatacg atcacattaa agacgttaac gatctgccag
    27001 agctgctgaa agcgcagatc gctcacttct tcgagcacta caaagacctc gaaaaaggca
    27061 agtgggtgaa agttgaaggt tgggaaaacg cagaagccgc taaagctgaa atcgttgcct
    27121 ccttcgagcg cgcaaagaat aaataagttc ttctggcgca ataaccctga acaccgggct
    27181 tcggttagta agggtttttt tatgcccgcg ataaataaac acaccttatt ccaccaccgc
    27241 ctgcaagcgt aataacgcct cttccaccac ctcatccgca gccagaccaa tacgctttgc
    27301 cagccgggcg cgtagatcca tcatccgcac ctgattcacc agcaccacgc cgtgcacatc
    27361 gccttcttcg caatgtaaag gaacgctaaa tccggcataa cgggcaaaat ttccgccctg
    27421 cgtaatgggg gccaccagcg tcattcccag ttgattaaag gcttgaacgg agagcacaag
    27481 cgcaggtcga ccagcacctt gctgttcatg gccgcttgct ggatcaaagc caaccagcac
    27541 aatgtctccc cgttcaaatt cacttttctt taccatattt cgtcacccgc aggggtggat
    27601 ttaccccaga catcctgctc gctaagttcc gcggcgttca tgtcacactg tgccagcagt
    27661 tcatcaagcg agtagcgcct ggagatgggt gtcagaatca gttggttgtt gctcacctgc
    27721 gcttccacgc tctgccccgg ctgtaagtta agttctttca ttacgatatt gggaatgacc
    27781 atacctgcac tgttccccca tctttttatg gtaatacgca tctgcacctc cttaagttat
    27841 acaaagtata actcacggtg ctacaggaaa cgttttaccc ctgcacattt gtgaacgcca
    27901 gcagagtttt ttatgcgatt gcagatatgg aaagcggctc ggagagaaaa gcaaaagatg
    27961 gaaaagttac aaaaaaaaat cgcgagatac atcgcataaa acaacgccac ccgaaggtgg
    28021 cgtgctttta ttattactta tccctgtcta accagtcgcc gctttcaatt agctttaatc
    28081 catcgacggg tcgttgataa acgtacatcc atgcactccc gtacggcgtc tgaatcaact
    28141 ggcgcgcgta ttcaccgccc ctggtgcgca aggcatcaag ttcggccagc gtggcgttgt
    28201 caatacgata aacttcaccg tgtactgttc cgttccccgg aactgcgcct ggatagtggc
    28261 ccaggctata caactggtag ttatcgatac tgaaatcgcc cagtaactgg gcattggtca
    28321 tccagtgact gttgccttgt ttgtggcgta aactgccgta gacaaatatt cgcattgcta
    28381 aaactcgaac tgatagagca aatccagtgc ctggtctaca ccagacacgg cttccagata
    28441 tagcttaggc atcaggcgat aacgtaacgt gagtgttgct atagagtcaa atatacccac
    28501 gccgtatttc acttgcagac ctggcaatac atagccgctg accactacct gggaggagtc
    28561 gcctactccc tgggtgtcga gcgctaaatt gcttacgcca aacgtctcgc cgattttacc
    28621 cacaatctgg ccactttgcg caacccccag gccaatcagc attgaggtca tcgccgcact
    28681 gtcgctctga tcgctctcca gcccttgtcc acgtagcaaa taagacaatg cagcttgttg
    28741 cgacatagcc gggtcagaga agatctccgc tttcggttcg tccgccagac cagtgacgcg
    28801 aactccggcg attacgtcgt cttctgtagc atccgggtta cgaatagctt caatattaag
    28861 atacggttga tctggcggac cagagaacag tagctcaccc ttacgcacaa tcagatcctg
    28921 accataggca tggaagcgcc cttcagggat gttgatctgc ccgttcaggc ccagcccttg
    28981 tttgtcctga acgacgttaa gatcgcccgt cagccgcgct ttcaggccaa aggcgtcaat
    29041 gcgcacattg ttgccaacgt ggacaatcag gttactgtta atcggaatcg acgccgtttt
    29101 cggctcttcc ggttgcaggt tatcgttaag catcaccaca tcgctggaga cgcctactgc
    29161 gctttccggc agatcgtgca ccacgatgcg cgcccacggg acatccacgc gaccatcgag
    29221 ggtaaacagg tttggtgtag cctcgaatac aacatctggc gatacatcca ttcgtaccat
    29281 cggcggcacg gtgatccgca ctttactgcc tttcgccgtt actcgtgccc gccagttttc
    29341 aatttggctc cagtcggcat caccgttcag gtagatttca ccctgctggg tccgtactgt
    29401 accggcaagc gtcgagcgca taccgttaaa gttgaccgca agctggctcg gctgcatatc
    29461 aaacggcata aagttgccgt cgatatccac acccgtaacc tgaagctgac caaacaactg
    29521 cgggctttgc acatcaccac ccagacgcaa gttggcactc accatccccg ctgctttttc
    29581 cccacgggta aagatggggt ttatcatcgc aaggttgaag ttacggatat tgacgttgcc
    29641 accaagatta cggcggcctt gcggatcggt cacctgcacc tgtccatcaa actggccgtt
    29701 attggtcagg cggatggtcc agcccaattc ggcacggttg ttacgcaatt ccgccgtcag
    29761 attcagtgtc tgaaacgcca ccggcagcgc cgcatcgttg acggtttgcg ttacctgcac
    29821 gttacgcccc gaaagggtga tactgccctg cggcagcccc tctttcgtgg tgtcccaggc
    29881 aacatccgct ttacccgtga agataccgct ggcctgagtg gtttctggca taaacggttt
    29941 cagcatggcg aggtcgaagc ggttgagatt caccaccgca cgcccttcgg cccccgcatc
    30001 gatagtttgc ggcacgcaca gttccgcatt cgggttaagc cagcagtgtg gcccgatgct
    30061 gattttttgc tccttattgc ggtaatccag cgcaatatcg cgggtcagcg accacgggcc
    30121 gaccggcgtc tggaagcggg tattgctaag agttcccttc cagcgttctt ctttgcgatc
    30181 aaaacttcct gccagattaa gctgcccgga gacaggctcg ccctgaatcc gcaactgtag
    30241 ctcgtgctgc ttttcgctgc ctttggcatt cagggtgacg aggttgatat ttacatccgg
    30301 ctgcgaaatt tgctcaacgc gtacgtcgag tttcccggcg atctgatcgg tggatttaat
    30361 gtcgccttcc acgcgaacct gcgccacgga aagttcctgc cagcgcaggc cgcgcgcggt
    30421 gatatctgcc agtagttgtg gcgcttccac cgtgccgcgt actttcacca gccctttcgc
    30481 tgtaccgcca agccccggca gcgcgttatc cagccccggc gcgttgatgg tggcatcaag
    30541 attgagatct tttaccccca gctcgccttt cacttcggca ctgtttggcc cgagttccag
    30601 atgaagccca gggatcatcc actgcatata actgttgcct ttcagcgtgc cgtcaacgtt
    30661 cactttgttc tgtttgacgt taccggtcag cttcagttct ggcacctcca tctgccaggt
    30721 gccgccgtac aggctaccgc gggttttaat caagccattg agtttcgacg gccactccgg
    30781 gaactctttg gcggtgttaa tgccattaag cgttagctca ccgcgccaac taatggcctg
    30841 ctgccagtcg agcaacgcct tgagttcagt tttcccttcc agcgccgcga cggtgagttt
    30901 gtcgagattg acctgctgtt cattaccttt ggcatcaagg gtaatggtgg ctggcgggat
    30961 ctcctgtccc ttcactgccg tacgcataga gagcgtgtaa tcggtcattt tgccggtaag
    31021 tttcagtttc agatcatccg cctgatactg cttctcacca gtgaacggcc agtaaagctg
    31081 tttgctgttc acttccacgt tgagcggcaa tccggcttcc gccagtcgcg tctgggcgcg
    31141 taaatccata tccaccggac cggaaagatt aacgccaatc tccagctgtt cgcgcagcgc
    31201 gccacccact tttagcttca ctttttcacc tttcaacggc tccacgttca gtgtgctgtt
    31261 gagggtgata tccaccggcc agttgtctga cagctgcgcc gtgccgctgg cgttgacgat
    31321 cccctggttg gaatcgatat ccagggcgtc cagtttagta ttgccgtcaa tgctgctcac
    31381 tttcagcagc atggtgcgca cggtgatgtc cgtgtcgccc gtcacacgta actgctcgcc
    31441 tttaaactct tcaatgttca ggttaagcgg caaatgcaag tcggtcattt ccggcaatac
    31501 cgggcgagaa aagagatctt tcagcgtttc gccgagcggc ttttcctccg gctgcggatt
    31561 ttcaattttc ggttcgacca cttcttcctg cgccacttcc gccactttcg gcagagcaat
    31621 cagcaggcct ttcagcgacg tcggtttcag ggtcagggtt ttctcctgcc agttcaggcc
    31681 ggaggtgaag tccatcaccg acaccgtggt gtcatcaatc ttgatgttga cgttgtccag
    31741 cgccacccgt gtcagggtga tgggatacgg cgtggagaga tccagcggac cgctatcttc
    31801 ctcttcttca acctgttcag aaggaggcat ttttttactg tcgatgttga cctgaatgtc
    31861 tttcagcgcc aggtcattaa tacaaacgct actgttccac aggcactcaa gaccgaccgc
    31921 cagatgcaga ttacccgctt ttaccgccac gcctggctgc tcataacgaa cgtcagacaa
    31981 ggtgagatcg cgccagccgc cggtgacctt gccaatatcc agtcctggca cccagcgatc
    32041 cgccgcttta aataccagat gcaggccgct ggtggtgccc accagaaacg ccaccgatcc
    32101 cagcaacagt aagataacga taaccacgcc gaggctgatt tttttccata aactcataat
    32161 tctggcccca gaccgatgta aaactgtaac ccgtgctcgt ctttatccgc gaccggtacg
    32221 gcaaaatcga gtttgattgg cccgaccggc gattcccagc gtacgccgac cccggtaccg
    32281 gttttaaagt cgctgcggcg aatatcgctt accgcttcgc cactatcgac aaacaccgcg
    32341 ccccaccatt ttccggtcac gttgtactgg tattccagcg atccggttat cagcttcgag
    32401 gcccctttca ggtcaccgtt ggcgtatttc ggggcgatag atttgtattt gtagccgcga
    32461 atactgcgat cgcccccggc gaagaaacgc agatccggcg gtactttgtc gaaatcaccc
    32521 gtttcaatcc agcccagcgt gctgcgtgtc acaaaacgat ggcgatcgta cagtgtgcgg
    32581 atccagacgt tctgcgcctg gaaaacggag aaatcgacat ctgagcccca ggccgtgttg
    32641 gagtagtcga tagagtagcg ttgcgagtcg ccccaggttg gcatcaggcc accacgagaa
    32701 cgcgtgcggc taatcatcac cccaggataa aacagcatcg tggtgttggt aatttcaccc
    32761 tgggtaaagt ggtcgaggct ccagcgcagg ttaatggcac gctgccagcc gctggagaga
    32821 tcccagtagc gagaagccac cagcgtagtg gagtcagatt cggtatcgtt caggtcagtg
    32881 cgcttaaaac cgccctgcac caaataatat tgttccagtg gattcttcag cagcggcatt
    32941 ttatagctga agtcgagggt ctgttccggc gcggaaatac tggtactggt ggtcagactg
    33001 tgaccataag agttcatcca cggctttttc cacgtcgctt tcacgcgcgg tcccacgtcc
    33061 gtagagtaac cgaccccggt ttcgatggtg ttttcagttc gcggcgaaac cacgcccgtc
    33121 aagggtaata ctttcgtttc gcgcgcttta tcaaattgtg gagccaccac caccgagtta
    33181 aaccagccgg tagcagaaag tcggcggttc agttccgcca gatctttcga ttcgtactca
    33241 tcgccctctt taaacggcac cagattttgc aggtattcat cgcggatttg tgatccttca
    33301 aaggtcacat gcccaaagcg gtaacgttcg ccactgttat aatcaatatc ccagaaggct
    33361 ttatgcaggc cgagcgcaat gcccagctgc gctttggtaa attcgctatc gaaataacct
    33421 ttacgcaacg caatgctggt taaggacttt ttgaaatttt cataatcgcc ctggttcagc
    33481 accgtgccaa tagccgggcg agtatcgagc aatttcaaat agtctttatc ggtccgcgcg
    33541 ccgccgcgca ataccacatc ggtgccgcca attaacaccg gcacacctgg cgtgactttg
    33601 gcgatcaata cctgccgccc tttctttggc ggtggacgga gatcaaattc aatggtcggc
    33661 tggtaataac ccagcgcttt cagaccttcg cggatggcat catcgacgcg tgcgcgaaag
    33721 cgacggtctg gcgtcacttc atcactttca atcgtagaaa gctgcgcacg aacgttcttt
    33781 tccagctgtc ccgataaccc ctcgacctgt agacggacgt tcgcggcgac ggcagatccg
    33841 cttaagcaga gtaagcttac acagcataac tgtcggatat agcgcacatt ttctcctgaa
    33901 tatccttttt tcctgcccct ggaacgccgt taaacggctt aacaaaaatc cagtaatatg
    33961 gattaaaaag cagactaaac cccaaatatt tcttatgttt tactttagac ctattcacgg
    34021 tggttattgt gtgcaaatac gcctcttgtt acaaccttaa ccccaatgac cgattttcgg
    34081 gagagcgaca ccatgagttt atttgataaa aagcatctgg tttcccccgc cgatgccctg
    34141 cctggacgta acaccccgat gcccgtagcc acgctgcatg cggtcaacgg tcactcaatg
    34201 accaatgtac ctgacggaat ggagattgcc atttttgcga tgggttgttt ctggggtgtg
    34261 gagcgtctgt tctggcagtt acccggcgtt tacagcaccg ccgcaggcta taccggaggc
    34321 tatacgccaa atccgactta tcgggaagtg tgctccggtg atacgggtca tgccgaagcg
    34381 gtacgcattg tttacgatcc ttccgtcatc agctatgagc agttgctaca ggtattttgg
    34441 gagaatcacg atcccgccca gggaatgcgt cagggcaatg accacggcac gcagtatcgt
    34501 tcagcgattt atccgctgac cccagaacag gatgccgcag ctcgcgccag tctggaacgt
    34561 tttcaggcgg cgatgcttgc cgccgatgat gatcgtcaca tcaccacgga aatcgctaac
    34621 gccacaccgt tttattatgc cgaagatgac caccagcaat atctgcataa aaacccgtat
    34681 ggttactgtg gaattggcgg aattggcgtc tgtctgccac cggaagcata gcgttacggg
    34741 tacaaatgta gattgttgat aaagtgcgct ttatttatgc cagatgcggc gtaaacgcct
    34801 taccaggcct acaaaatcgt ccaaattcaa tatattgcaa ggactgcgta ggcctgattg
    34861 gcatagcgca tcaggcagta ttgcatttat cagcagtctg aattttaacc ctctggcgac
    34921 tttacagtac cttacgctat actagccact gaaaatgccg gttcactttc ttcgaatcgg
    34981 ctttcaatgt gtatttcaca caaattaatc aacttcccct tccgaggatc tggcctgaaa
    35041 ggtcggataa gatatgttaa acagtatttt agtcatactc tgcttgatcg ctgtaagtgc
    35101 gttcttctcg atgtccgaga tctcacttgc cgcctcacgc aaaatcaaac ttaaactgct
    35161 ggctgatgaa ggcaatataa atgcccaacg cgttctgaat atgcaggaaa atcccggcat
    35221 gttctttacc gtggtccaaa tcggtctgaa cgcagtggcg attctcggcg gtatcgtcgg
    35281 tgatgcggca ttttctccag cttttcacag cctgttctcc cgctatatgt cggcagagct
    35341 ctctgagcaa ctgagcttta ttctctcttt ctcgttagtg actggcatgt ttatcctgtt
    35401 tgcggattta accccgaaac gcatcggtat gattgcgcca gaagctgtcg ctttgcgtat
    35461 catcaacccg atgcgcttct gcctgtacgt ttgcaccccg ctggtgtggt tcttcaacgg
    35521 actggcgaac ataatcttcc gtattttcaa actgccaatg gtacgtaaag atgacatcac
    35581 ttctgatgac atctacgcgg tagtggaagc cggtgcgctg gcgggcgtgt tacgtaaaca
    35641 ggaacacgag ctgattgaaa acgtctttga gctggaatcc cgtaccgttc cgtcgtcaat
    35701 gacaccgcgt gaaaacgtga tttggtttga tctccacgaa gatgagcaaa gcctgaagaa
    35761 taaggtggcg gaacatccgc actctaagtt cctcgtctgt aatgaagata ttgaccacat
    35821 catcggctat gtcgattcta aagacctgct gaaccgcgtg ctggctaacc aaagcctggc
    35881 actgaacagc ggcgtacaaa ttcgcaacac gctgattgtg ccggatacgt taaccctttc
    35941 agaggcgttg gaaagtttta aaaccgcagg tgaagacttc gcggtgatca tgaacgagta
    36001 cgcgctggtg gtggggatca tcaccctcaa tgacgtgatg accacgctga tgggcgatct
    36061 agtcggtcag gggctggaag agcagattgt cgcccgtgat gagaactcat ggctgattga
    36121 cggcggcacc ccaattgacg acgtcatgcg cgtgctggat attgacgagt tcccgcagtc
    36181 gggcaactac gaaaccatcg gcggctttat gatgtttatg ctgcgtaaga tcccgaaacg
    36241 caccgattcg gtgaaattcg ccggctacaa atttgaagtg gtggatatcg ataactaccg
    36301 catcgaccag ctgctggtga cccggatcga cagcaaggcc accgcccttt cgccaaaact
    36361 gcctgacgct aaagataaag aagaaagcgt cgcgtaaccc ccagaaacat caacggctcc
    36421 tgaatcagga gccgtcttat tactgcatag cactttggtt aagccatctc tgtttgcaga
    36481 cgcataacct gacggttaac ttcggacatc actgacaaat gcagcttatc cttcactttt
    36541 gggataagaa tcttaccctt atcaaattca aaagcgccaa cgtccttgat gtataaccgt
    36601 ccacggaaca ggatctttac gtacttcgcc acctgaagtg ggttgtaccg ttggaaaatt
    36661 ttcattgtta tctcctgctg agtattacgc ctgtgcggtg ccacaatcgg cccaactatt
    36721 atgaggcgca aattttaatg cttagtgact atagactatc cgggcaatgt ttccaccgcg
    36781 tataactttt tttacctaaa ggttacaatt attcagaatt atctttttac cgaagcgcgg
    36841 tcttcagtat aagcattcat ttttcatatg atttgtgcgc ttgaccgcaa actggcatca
    36901 cacttgcggg aaattcgata aatagcacat atgattaaaa ctcagaccca agtggtcgga
    36961 tcacctgcat atcataagaa ggaaacacca tgaccctacg caagattctg gcactcacct
    37021 gcctgctgtt gccgatgatg gcttccgcac atcagttcga aaccggtcag cgagtgccgc
    37081 cgattggcat taccgatcga ggcgagttgg tgcttgataa agatcagttt agctacaaaa
    37141 cctggaacag cgcacagtta gtgggaaaag tgcgagtact gcaacatatt gctggtcgca
    37201 cctctgcaaa agagaaaaac gcgacgctga ttgaagcgat taaatcagcg aagttaccgc
    37261 acgatcgcta ccagaccacc accattgtta acaccgacga cgcgattccg ggttcaggga
    37321 tgtttgtgcg cagcagtctg gagagtaata aaaagcttta tccctggtcg cagtttattg
    37381 tcgatagcaa tggcgtcgcg cgcggtgcct ggcagctgga tgaagaaagt tccgctgtag
    37441 tggtgctgga taaggatggt cgcgtgcaat gggccaaaga cggggcgctc acacaggaag
    37501 aggtgcagca agtgatggac ctgctgcata aattaattaa taaatagaca ctctgaatcc
    37561 cggattcagg aacgactcgc gcggagtgta atccagcggt ttaccctgcc agtcatgaac
    37621 gtgcgctccg gcagctgcag ccacagcatg accagcggcg gtatcccaaa tattcgttgg
    37681 tccgaagcgc gggtacagct gcgcctgccc ttccgccacc aggcagaatt tcagcgaaga
    37741 gccgatggac gtggtctgat gttcgccaag ctgttgcaga tactctttca gctccgcatc
    37801 tgcatgggaa cggctgataa ccaccagcgg cgggcgcgca tcgcggacct gaatctgctt
    37861 gcgcacaccg cactcttctt tccaggcctt gccttctgcc gcgctgtaca ttatgttcat
    37921 taccggcgca tacaccacac ctaaaatcgg tttgccatgg tcaatgagcg caatgttaac
    37981 ggtgaattcg ccattacgtt taataaactc tttagtacca tccagcgggt ctaccagcca
    38041 gtaacgctgc cagtgctgac ggacttccca accgggagga tcttcttcag aaaggaccgg
    38101 aatatccggt gtcagcgtac gtaaaccgtc catgataacg gtgtgagcgg caatatccgc
    38161 tgccgttacc ggagaattgt ccgctttgct gacgacgtcc atcggtttcg tcccgtcgta
    38221 gacctgcata atggcatcgc ctgcattccg tgcaagctgg catacttgat ctaacatttc
    38281 tccacctcgt ctctgtgagc ggtgttaact tattgtttta cttataccct atcgttaatg
    38341 aatgcgccaa ctgtgatagt gtcatcattt tcaaagcgta aaattgtggc attcttcact
    38401 gttctataag taaggcgttt attctccctt ttctttcgta ttcccgatga taaaaggatg
    38461 tccctgatga ttaagtttag cgcaacgctc ctggccacgc tgattgccgc cagtgtgaat
    38521 gcagcgacgg tcgatctacg tatcatggaa accactgatc tgcatagcaa catgatggat
    38581 ttcgattatt acaaagacac cgccacggaa aaattcggac tggtacgtac ggcaagcctg
    38641 attaacgatg cccgcaatga agtgaaaaac agcgtactgg tcgataacgg cgatttgatt
    38701 caggggagtc cgctggccga ttacatatcg gcgaaaggat taaaagcagg tgatgttcat
    38761 ccggtttata aggcgctgaa tacgctggat tatacggtcg gtacactcgg caatcatgaa
    38821 tttaactacg gtctggatta cctgaaaaat gcgttggcgg gagcgaaatt cccttatgta
    38881 aatgccaacg tcattgacgc cagaaccaaa cagccaatgt ttacaccgta tttaattaaa
    38941 gataccgaag tggtcgataa agacggaaaa aaacagacgc tgaagattgg ctatattggc
    39001 gtcgtgccgc cgcaaatcat gggctgggat aaagctaatt tatccggaaa agtgacggtg
    39061 aatgatatta ccgaaaccgt gcgcaaatac gtgcctgaaa tgcgcgagaa aggtgccgat
    39121 gtcgttgtcg ttctggcgca ttccgggcta tctgccgatc cgtataaagt gatggcggaa
    39181 aactcagttt attacctcag tgaaattcct ggcgttaacg ccattatgtt tggccatgct
    39241 cacgccgttt tcccaggtaa agattttgct gatatcgaag gggctgatat cgcgaaaggc
    39301 acgctgaatg gtgttccggc ggtaatgccg ggcatgtggg gcgatcatct tggggtggtc
    39361 gacttacaac tcagtaataa cagcggtaaa tggcaggtga cgcaggcgaa agcggaagca
    39421 cggccgattt acgacatcgc caataaaaaa tccctcgcgg cggaagacag caagctggta
    39481 gaaacactca aagccgatca cgatgccaca cgccagttcg tcagcaagcc aatcggtaaa
    39541 tccgccgaca atatgtatag ctatctggcg ctggtgcagg acgatccgac cgtgcaggtg
    39601 gtgaacaacg cgcaaaaagc gtatgtcgag cattacattc agggcgatcc ggatctggca
    39661 aaactgccgg tgctttcagc tgctgcaccg tttaaagttg gtggtcgcaa aaatgatccg
    39721 gcaagctatg tggaggtgga aaaaggccag ttgaccttcc gtaatgccgc cgatctttat
    39781 ctctacccca atacgctgat tgtggtgaaa gccagcggta aagaggtgaa agagtggctg
    39841 gagtgctccg ccggacagtt taaccagatt gatcctgaca acacgaaacc acagtcactc
    39901 atcaactggg atggtttccg cacctataac tttgatgtga ttgatggtgt gaattatcag
    39961 attgatgtta cccagcctgc ccgttatgac ggcgagtgcc agatggttaa tgccaatgcg
    40021 gaaaggatta agaacctgac ctttaatggc aagccgattg atccgaacgc catgttcctg
    40081 gttgccacca ataactatcg cgcttacggc ggcaaatttg ccggtacggg cgacagccat
    40141 atcgcttttg cttcaccgga tgagaaccgc tcggtgctgg cagcgtggat tgctgatgag
    40201 tcgaaacgtg cgggggaaat tcacccggcg gcagataaca actggcgttt agcaccgata
    40261 gctggcgata agaaactgga tatccgtttc gaaacctctc catcagataa agccgcggcg
    40321 tttattaaag agaaagggca atatccgatg aataaagtcg cgaccgatga tatcgggttt
    40381 gcgatttatc aggtggattt gagtaagtaa tacacttctt tttcggccta taaatcatca
    40441 accgcatccg gcacttttgt cggatgcgat gctggcgcat cttatccgcc ctacaagtca
    40501 tgaaccgtag gccggataag cgcagccggc agttatgccg cacgttcatc ccgcaccgcc
    40561 aacacctcgg gcaaattcaa ctcaatccag tccgccagtg cagcaacctt ttcgctcacc
    40621 tgctcgccca gcggcgtgag gctatattcc acatgcggcg gcaccaccgg atacgcgata
    40681 cggttaagaa aaccatcctg ttctaacgcc tgtaacgact gcgcaagcat cttttcactc
    40741 accccaccga ttttgcgccg caggtcgcta aagcgatgag taccttcgcg tagcgccacc
    40801 agaatcaaca ccccccaacg gctggtgacg tgtttcaaca cctcgcgcga cgggcactgt
    40861 tccgcaaaga gattaccctc tttcagttgt tgtgacaggc taacctgact catttcatac
    40921 ttaccttttt gtacgtactt actaaaagta agtttaggtg ttagcgtatt taaacacaag
    40981 acaaaacgat ggagacttcc catgatcgct attactggtg ccactggcca acttggtcac
    41041 tatgttatta aatccttgat gaaaacggtt cctgccagcc aaatagtggc tatcgttcgt
    41101 aatccggcaa aagcccaggc actgacagca caaggcatta ccgtgcgtca ggctgactac
    41161 ggcgatgaag ccgcactgac atctgcactt cagggagtgg aaaaactact gctgatctct
    41221 tccagcgaag tgggtcaacg tgccccgcag catcgtaatg ttattaatgc cgcaaagacg
    41281 gctggcgtga aatttatcgc ttataccagt ctgcttcacg cggataaatc tccgctcggc
    41341 ctcgccgatg agcacatcga gacggagaaa atgttggctg attctggcat cgtttacacc
    41401 ctgctgcgca acggctggta caccgaaaac tatctcgcca gcgccccggc agcactggag
    41461 cacggcgtat ttatcggtgc cgcgggcgat ggcaaaattg cctcggcaac gcgggcagat
    41521 tatgcggcag ctgcggcacg cgtgattagc gaagccggtc acgaaggcaa ggtttacgag
    41581 ctggcgggcg atagtgcctg gacgttgaca cagttagcgg cagagctgac caaacagagc
    41641 ggcaaacagg ttacctatca aaatctgagc gaaaccgatt tcgctgcggc gctgaaaagc
    41701 gttggcctgc ctgacggact ggcggatatg ctggcggatt ctgacgttgg cgcatcgaaa
    41761 ggcggtctgt ttgatgacag caaaacgctg agcaaattga ttggccgccc aacgacaacg
    41821 ttagccgaaa gcgtaagcca tctttttaat gttaataaat agttaattaa agtggcatcc
    41881 tcccgcatcc tctctgataa tgacgggatg ccgggagcaa tcatgtctgc ttcctgaacg
    41941 tttcttctga cagaccaatg gatgccagta atgattagcg gcgtgctgta cgccctgtta
    42001 gcagggttga tgtgggggct tatttttgtc gggccgttga tcgtgccgga atacccggcg
    42061 atgttgcagt cgatggggcg ttatctggcg ttagggttaa ttgcgctacc cattgcctgg
    42121 ctgggacgcg tgcgtctgcg tcagttggcg cgtcgcgact ggcttaccgc cttgatgctc
    42181 actatgatgg gcaacctcat ctattacttc tgccttgcca gtgccattca acgtactggc
    42241 gcgcctgttt ctacgatgat tattggcacc ctgccggtgg tcattcctgt ctttgccaat
    42301 ctgctttata gccagcgcga cggcaaactc gcgtggggaa aactcgcccc ggcactgatt
    42361 tgtattggca tcggcctggc gtgtgtgaat attgctgagt taaaccacgg actccccgat
    42421 tttgactggg cacgttatac ctctggcatc gtgctagcgt tagtttccgt ggtctgctgg
    42481 gcatggtatg ccctgcgcaa cgcccgctgg ctgcgggaaa atcccgacaa acatccgatg
    42541 atgtgggcga cggcgcaggc gctggtcacg ctgccggttt ctctcatcgg ctatctcgtc
    42601 gcctgttact ggctgaatat acaaacgccg gacttctcct taccttttgg cccccgtccg
    42661 ctggtgttta ttagtctgat ggttgcgata gccgtgcttt gctcatgggt tggcgcactc
    42721 tgctggaacg tcgccagcca gcgattaccg acagtgattc tcgggccgct gatcgttttc
    42781 gaaacactgg caggtttgct gtacaccttt ttgatacgcc agcaaatgcc gccgctgatg
    42841 acgctgagcg gtatcgcgct gttagtggtt ggcgtggtca ttgcagtcag agcaaaaccg
    42901 gaaaagcctt taactgaatc tgtctcagaa agttgacata ctggcagtga gttaaataag
    42961 cctctgctac gtaagggtta tagcatttgc cttaaagatg catttaaaat acatcttatc
    43021 ttattaagaa tgaggtatca gctatggctt atcgcgacca acctttaggt gaactggcgc
    43081 tctctatccc tcgcgcttcg gctctgtttc gtaaatatga tatggattac tgctgcggcg
    43141 gtaagcaaac gctggcgcgt gcggcggcac gtaaagaact ggatgttgag gtcattgaag
    43201 ctgagctggc aaagcttgct gaacaaccga ttgagaaaga ctggcgtagc gccccgctgg
    43261 cagaaatcat cgaccatatc atcgtgcgct accacgatcg tcaccgcgag caactgccgg
    43321 agctgatcct gcaagcgact aaagtcgagc gcgttcacgc cgacaaaccg agcgtgccaa
    43381 aagggctgac aaaatacctg accatgctgc atgaagagct ttccagccac atgatgaaag
    43441 aagagcagat cctcttcccg atgatcaaac aaggcatggg cagccaggca atggggccaa
    43501 tcagcgtaat ggaaagcgag cacgatgaag cgggcgaact gctggaagtg atcaaacaca
    43561 ctaccaataa cgtcacaccg ccgccagaag cctgcaccac ctggaaagcg atgtataacg
    43621 gcattaatga actgattgat gacctgatgg atcacatcag tctggaaaac aatgtactgt
    43681 tcccacgcgc gctggcgggt gagtaatcta aaagctggat ggcattgcgc catccagcat
    43741 gataatgcgg ttatttccgc agttcagcag cccgcttctt accaataaac aaccagccca
    43801 gccccagtgc gataaaccac agcggggtga ccaatagcgc ctggcgagtg tcatcttcca
    43861 gtgtcagcaa cacgaccacg aacacaaaga acgccataca tacccagcac atcagcttgc
    43921 cgagcggcat cttgtagatc gacttctcat gcagatgagg acgctgtttg cggtaaacca
    43981 ggtacgagca aaggataatc gtccagacga acataaacag aatcgcggaa acggttgtaa
    44041 tcatcgtgaa cgcgccaatc acgctaggat tcacatacag catcaccacg ccaccgagca
    44101 ggcagatgca ggagaaggtc agccctttcg ctggtactgc gcgcttagaa agtttagcga
    44161 acgctttcgg tgccacacct tcctgcgcca gaccaaacag catacggctg gtagagaaga
    44221 cgccgctgtt agcggaagac gccgcagagg tcagcaccac aaagttgatc acgcttgcgg
    44281 cagcaggcag ccctaccaac acgaacagtt caacaaacgg gcttttctcc gggactaccg
    44341 aactccacgg cgtcacggac ataatcacaa tcagcgcgaa gacgtagaac ataatgatac
    44401 ggatcggaat ggagttaatc gcgcgtggca gtgatttctc cggatctttg gtttccgcag
    44461 ctgttgtacc taccagctca atccccacga aagcgaaaac cgctatctgg aatccggcaa
    44521 agaagccact taaacctttc gggaaccagc cgccgtcatt ccacaaatgc gcgaatgacg
    44581 cttccacacc ggtcggtgac tgaaagtgca tcgccaccat gaccaggccg acgacaatca
    44641 gcgacacgat ggcgacgatt ttgatcatcg caaaccagaa ctccatctca ccgaacattt
    44701 tcacggtggc aaggttgagc gtcaacagca gcactatcac cgccagcgag gcgacccagt
    44761 cggagagatc ggggaaccag aactgagcat aagcagtgat cgccaccacg tctgccatac
    44821 cggttacaac ccagcagaac cagtaagtcc agccggtgaa atatcctgcc cacggcccga
    44881 gtaaatcgga agcgaagtca ctaaaagatt tgtattccag attcgaaagc agcaattccc
    44941 ccattgcccg catcacgaaa aagagcataa aaccgatgat catataaacg aaaatgatcg
    45001 acggcccggc aaggctaatc gttttgccag accccataaa caaccccgta ccaatggcac
    45061 cgccaatggc aataagctga atatgtcggt ttgtgagatt gcgccgtagc gactgttcag
    45121 ccggagcctg atcatcggca acgactttta cctgatctac catgtttttt tcttcctgta
    45181 cctgtctgtg ttgttcaggc tctacggcct ttagtcagtc tatgatacga cgaatctgta
    45241 tcgggactca tcgatattag gtaacaatac gcgggatgaa tactaagatt tagatctaat
    45301 gttaatttta tgtttaaagt gagtgtcata tcacggtgat aacgcgaaac agctcacaaa
    45361 aatacacgct tacggggtct ttgcaacaca aaatagcgcc gtttggcaaa ctgaagggtt
    45421 tattgctgaa tgcctgctcc cctctggttc gaggggaaca gaatgcgctg cttagaggat
    45481 ttccagcagt tcgacttcaa acaccagggt gctgaacgga gggatggatg cgcctgcgcc
    45541 gcgctcgcca tatgccagtt cctgcgggat agtcagttcc catttagaac ctaccggcat
    45601 cagagtcagt gcttcaatcc agccagggat cacgccatta accgggaatt cagcgggttc
    45661 accacgagca acggagctgt caaacacggt gccgtcgatc agtttaccgg tgtaatgaac
    45721 acgaacgcgg tcagtacgtg ccggaattgc gccttcaccc tggttgatca cgcggaattg
    45781 caggccagat tcggtgctgt tcacaccttc ttttttggca ttttcttcaa gatatttcac
    45841 accttcggca gccatcgcct ggaaacgctg acgacgaacg gcatcggcgc gttcgtggat
    45901 ttcacgcagc gcgcgatgca ccacatcaac cggaacagcc ggatgtttgc cttccagcgc
    45961 atctgcaata ccagccacca gcgcctccgg cagcagccct tgcaggccag attcactcag
    46021 ttgttggcct acctgtaaac caatgccgta gcttgcttgc gcttcgatgg tgtcaaaagt
    46081 tggggtggtc atcgtatttc ctttcttagg gtataaaagt agcgggcagc atatcagcca
    46141 cacttctttg ggtaaaactt tgtcgcagga atgatgacaa atcccgggga aaaagaaaca
    46201 atagcaatat cccgtatgaa tataataaag gcgggtttac cacggacatc atagcgttag
    46261 cttattcata ggctatgatt gaggaacaag acgcggagca ggaggaaacc atgcccgggc
    46321 gctttgaact aaaaccaacc ctggagaaag tctggcacgc gccggacaat tttcgcttca
    46381 tggacccgct gccgccgatg catcgtcggg ggatcattat tgccgccatt atattggtgg
    46441 tcggatttct gcttccatct gatgatacgc ccaacgcgcc ggtggtgacg cgtgaagcgc
    46501 agttagatat tcagtcgcaa tcacaaccgc cgacagaaga acagctgcgg gcgcaattag
    46561 tcacaccaca aaatgatcct gatcaggtgg ctccggtcgc tccagaacct atacaggaag
    46621 gccagccaga agaacagccg caaactaccc aaacacaacc attccagcca gatagcggaa
    46681 ttgataatca atggcgctct taccgtgtcg aacccggtaa aacgatggcg cagctgttcc
    46741 gcgaccacgg actgcccgct accgatgtct atgcaatggc gcaggtagaa ggcgcgggta
    46801 agccgctgag taatttgcaa aacgggcaaa tggtgaaaat ccgccagaac gccagcggcg
    46861 tggtgacggg cttaaccatt gatacgggga ataatcaaca ggtcctgttc acccgccagc
    46921 cggatggcag ttttattcgt gcgcggtaga tgaagggtca accaaaagcc agctaaggat
    46981 tgtctctttg atgaccttac gtctggcttc cagtgcctgg ggggaaacca tactgatatg
    47041 ataaaccagg ccaagcgtat gctggttgat caaataatat ccgccaagcg cagcaatatt
    47101 aatattcacc tgcaatgggt cgatatctgg cttaaaaata ttgtgtttct tcccttcatc
    47161 caataaggat tccattaact gcaagtgcgc atggttaatt tctaagagac gctgtgattt
    47221 tgcataatgc acacctttac tttgattttc actatgcaca atttttaaaa accagggatt
    47281 agcaatataa taatcccatg taaaatcaat aattttctca atggcttttt gtggcggaag
    47341 atctgagaaa tcaagggcct tttctttttg tcgaatatcg ttccaggtat attccagtac
    47401 ttcaataaat aaattttctt tattaccaaa gtgatgataa accgtctgtt tactacaccc
    47461 cgcagcctta acaatattat cgaccctggc cccttcataa ccatattcgg caaattcatt
    47521 aaccgcgcat aacagcagct tttccttcag gctctgtacg ttgctggtat caagatacat
    47581 aacgcttccc cacgacctct tcaagataac tatcttaacc cgattaatta gaagctccag
    47641 taaaaaggat aaaaacttgt actttcatca agttatcaaa tgtcctgtga tcactatcgc
    47701 atatcaacca accagatggt tgatctttct tgcggcacgt cgcaagctaa ttgtcactta
    47761 gaaaacaata ttcaaaaaaa gagagctatt gtatgaaatc cactcgtcct gttgccgtga
    47821 ttaccggagc cgctcgtggt attggaaagg gctgtgcact ggagcttgct cgtggcggat
    47881 ttaacctgct gattaacgat cttcccgatg ccgacagcgt agaaaaactg catatcacac
    47941 aacaagaatg tatagctgaa ggcgtggaag tgatttgctt ccctgccgat gtcggcgatc
    48001 tctccttgca tgaagagatg ctcgacgcgg cgcaaaacct gtggggacgt ctggactgcc
    48061 tgctcaacaa cgcaggcatt tcagtgaaaa aacgcggtga cctcctcgac ctcgaaccag
    48121 acagcttcga tcaaaacatt gccattaaca cccgcgcgcc gttcttcctt gctcaggcat
    48181 tcagtaagcg tttactggca cagccgaaac cggaagcgga actgccgcac cgctcgatta
    48241 ttttcgtcag ttccatcaac gccatcatgc tggcgatgaa tcgcggcgaa tacaccattg
    48301 ccaaaaccgc cgtttctgcc gctgctcgtc tatttgcagc tcgcctttgt aatgaacaaa
    48361 ttggcgttta tgaagtgcgc ccaggtctca tcaaaactga tatgactatt ccggcaacgg
    48421 cttattacga cgaactgatt gccaaaggtc tggtgccgtg gggacgttgg ggttatccgg
    48481 ctgatattgc ttccactgtc cgcgcgatgg cggaaggtaa actgatttac acctgtggtc
    48541 aggcggtcgc catcgacggc ggcttaagta tgccgcgctt ctgaggctga atcatgagag
    48601 atctgttaca acgcccggat ttattcagta tcaataccgc aacactgggc tataaaacgc
    48661 cgctacccgc cattattgat gcctgcgccg cgcgtggtat tggcgcgatt gctccctggc
    48721 gcagggagtt gcaaggtgaa gatctccagc aaatcgccca ccagcttgcc gccagtaaca
    48781 tgagcgtttc cggtttgtgc cgtagcactt actacaccgc gccgacactg gcggaacgca
    48841 aactggcgat tgatgataac cgccgggcgc tggacgacgc agcggtgctt aacgccgcct
    48901 gttatatgca ggtggttggc ggtctgccaa cgggcactaa agatctatat gaagcgcgag
    48961 aacaagtgaa acaagggatt cgccagttgc tgccacattc gaaagatgtc ggcgtgccaa
    49021 ttgcgctgga gccactgcac ccgatgacag ctgccgatcg ctcttgcctg tgcacgttac
    49081 gccaggcgct ggactggtgt gatgaactcg atcccgatgg tgagtttggc ctcggcgtgg
    49141 cggtggatgt ttatcacgtc tggtgggatc cggatctcgc cagtcagatc ctgcgtgccg
    49201 gaaaacgcat cctcgcgttt catgtttccg actggttagt gccgaccact gatctggtca
    49261 atgaccgtgg tatgccggga gatggcgtca tcaatattcc gtcaattcgt cggctggttg
    49321 aaaacgccgg atttaatggc gctattgaac tggaaatatt ctcgccgtac tggtggcaaa
    49381 aagatattaa cagcacgctg gatattagcg tcgatcgcat cgcgcattat tgttaaggaa
    49441 tgatcatgag tgaccaaccc gttctgttca gcagagcggc ggcttcctgc cgcctgacat
    49501 tgaaccgtga agataaatgt catgctatta acgaagagat gatcgaatct ctcgaccatt
    49561 atttaaatga aattgaaaac gacaccacat tacgattagt cgaattaacg gcaaccggcg
    49621 ataaattctt ttgtgcgggc ggcgatatta aatcgtggtc ggcctattcg ccattagata
    49681 tgggcagaaa atggattaaa cgcggtaatg acgtttttaa tcgcctgcga aacttacccc
    49741 aattaaccgt tgcgaatctc aacggtcata ccatcggcgg tggtattgaa ctggccttgt
    49801 gctgcgatat tcgtattgcc cgccccggcg cgaaattctc taacccggaa gtgatgctcg
    49861 gcatggtgcc tggctggatg ggcattgaac gtgtgcttaa tcaggttggt ccggtggtcg
    49921 gtcgccagat gctgatgctg ggtaaacgcc tgacggcgca ggaagcccag gcggcgaatt
    49981 taattgatga agtggtagaa aaagaacagg tggaaagctg gatggcgaac cagttagcgc
    50041 agctggaaaa atgcggcccg gtggcactgg cgcatattaa gcaactgatt ctggcactgg
    50101 aaaataaaca tgccgattac ccgcaccagc tactggccgg attaatgtct gccactcagg
    50161 attgccagca ggcgacgcgc gcctttgccg aaaaaagtag cgtgagattc cataatcaat
    50221 aaggaaattg tatgcgtaag ataacaaccg ccgaggcact ggcggcgcaa attcaggacg
    50281 gtgcgactat tgctattagc ggtaacggcg gcggtatggt ggaagccgac catattctgg
    50341 ctgctattga agcgcgtttc ctgcaaaccg gacaccctcg cgacctgacg ctaatccact
    50401 cgctgggtat tggcgatcgc gactgcaaag gcactaatcg ttttgcgcac gcagagatgc
    50461 tcaaacgcat tattgccggg cactttacct ggtcgcccaa aatgcaggcg ctggtaaaaa
    50521 ataacacgat tgaagcctac tgctttcctg gtggcgtgat tcaggcactg ctacgggaga
    50581 tcggcgccgg acgtccgggg ctttttaccc acgttgggct gggatcgttt gttgatccac
    50641 gcaatggcgg cggtaagtcg aatgaatgca ctaccgacga gctggtagaa ctgattgaaa
    50701 tcgacggtga aaccaaactt cgttatcgcc ctttcaaagt ggattacgcg attttgcgtg
    50761 gcacttatgc cgatcctcga ggcaacgtca gccttgaaga agaagcgatt gatatggata
    50821 gctattccat ggcgctggca gcacacaaca gcggcggcaa agtgttcgta caggtacgcg
    50881 atgtgctgga agctggcgcg attgaaccac gccgggtcaa attaccgggc attctggttg
    50941 atggcatcgt tgaacaccgc gaacaaccac aaacctatct tggcggttac gacctgacca
    51001 tcagcggcca acatcgccgt ctgagttcta acgacgctat tgaactggtt agtcatccgg
    51061 tacgtcgcct gattgcccgt cgggcagcac gcgaactggt agctggcgct tcaaccaact
    51121 ttggctttgg tattcccggc ggcattccag gagtagcgct gcgcgaaggc gttccttacc
    51181 aaagtttatg gctgagcgtc gagcaaggcg tacataacgg catgatgctg gatgatgcgt
    51241 ttttcggctg agcccgcaac gccgatgcca ttattccatc actcgatcaa tttgagttct
    51301 acagtggcgg agggatcgat atcaccttcc tcggcatggg agagatggat cagtacggta
    51361 acgtcaacgt ctcccatctc aatggcaatc tgattggccc cggcggattt ctcgaaattg
    51421 cgcaaaatgc ccgtaaagtg gtgttctgcg gcacgttcga cgctaaaggc agcaagatcg
    51481 atataacacc agatggcttg catatcgccc agtcaggtca aatccctaaa ctggttacca
    51541 aggtggaaaa aatcactttt agcgccgcct acgcacagca aagtggtcag gaagtgttgt
    51601 atatcactga acgcgcagta ttccagttaa cggcagaagg cgttgaatta attgaaatcg
    51661 cgccgggtgt ggagattgag cgcgacattc tgccgtatat ggctttccgt ccaattatca
    51721 agcacccacg cctgatggaa agtagcctgt ttacgccgat ggaggatgca tgagtcagct
    51781 tgatgacacc atccttgatg cgctgacgca cgttactttc ccaaagggtt ttgcacaggc
    51841 agagcccgca tgggttgtca cggtagacgg tgttgattac ccactctggc aaacagatgc
    51901 cctggtagtc ggcagtggtg cagccgggct gcgtgcagct gtggaactta aacgccgcca
    51961 gcaaaatgtg ctgatcgcca ccgccgggtt atatatgggg acgtcggcat gttctggttc
    52021 cgataaacag acactgttta ccgccgctac cgcgggcaac ggcgacaact tcaccaaact
    52081 ggcagaggca ctggcgagcg gtggggcgat ggatcacgac accgcttatg tcgaagcggt
    52141 aggttctctg cacactcttg gcgggttgca atatcttggt ctggaattac cggaagatcg
    52201 ctatggcgcg attcttcgtt atcaaaccga ccatgacgaa gccgggcgtg caacctcgtg
    52261 tgggccgcgt acctcaaggt taatggtgaa agtgctgttg gaagaagtac agcgcctcgc
    52321 cattccagtg ttgaccagtg caacagtgat taaactgctg catcagcgtg acgaaaacgg
    52381 cgaagaccgt gttgcggggg caatcctcgc gaccggtcat cgcgcccata acccttgggg
    52441 gctggcaatt gtgactgcgc ccaatgtggt actggcaaca ggagggcctg gcgagcttta
    52501 tcgcgacagt gtgtacccac acaaatgttt tggctcgctg gggctggcgc tggaggaagg
    52561 cctgacgcta accaatctga ccgaaagcca gtttggtata ggcacgccgc gtagcacgtt
    52621 tccgtggaat ttatccggca cctatgtaca ggtgatcccg tatatctatt ccgtggatgc
    52681 tgagggtaac gagtataact tcctcgcgga ttactatcgc accacccagg agctggcttc
    52741 aaacattttc cgtaaaggct atcagtggcc gttccacgcc actcgggtga tggattttgg
    52801 ctccagcttg ttagatatgg cagtagcgca agagcagcaa tcagggcgtc aggtatttat
    52861 ggatttcaat cgcaatcctg aagcggtgcc gggtgacctg ccgttctcat tagatcgact
    52921 ggacgacgac gttcgcgcgt atctggaaaa taacgacgct ctggcaccat cgcccatcga
    52981 acggctgcaa cgaatgaatc cgctgtctat ctcgctgtat aagatgcacg gttacgatct
    53041 caccacacag cctttgcagt ttgccatgaa taatcagcat atgaatggcg gcattgaagt
    53101 ggatatctgg ggacaaacct ccctgcccgg ctgtttcgcc gtgggggaag ttgctggcac
    53161 acacggcgtc actcgccctg gtggtgcagc attgaatgcc gggcaggttt ttgctgttcg
    53221 tctggcacgt tttattggtt gcacgcaaaa gcggaatatt gatggagata tagcacagct
    53281 ggtagctcct acactggctt ctataagaga gatcattact caggcgcacg ataacgggac
    53341 cgggatgccg ttgtcggttg tgagagaaaa aattcaggca cgaatgtctg accatgcggg
    53401 atttatttgc catgccgata aagtccgacg cgccactcgc gatgccctgc tattgagcga
    53461 atttgtccaa cggcatggat tggctatcaa acatgtgggt gaagttgccg agctgtttat
    53521 gtggcggcat atggcactga cttctgccgc cgtattaacg caattaacgc attatattga
    53581 cgcaggtggt ggtagtcggg gagcacgtat tattctcgac agggatggaa attctattcc
    53641 gcaaacacga aatggttttt gtgatgcctg gcgctttcgt tcagagcgta ctgaggataa
    53701 aaaagataaa ctacttattc attattgcaa cggtatcttt cacgtcagag aaacacctat
    53761 tcgtgagttt cctattatcc gaggtatttg gtttgaaaaa aactggcctg gttttcttaa
    53821 tgggacaatt taccagccac aggatgaatg atattgcaaa ggttaatcac tatgcgaaat
    53881 ataattaaat ctattaatgc tctgcttgca gcattgaaca ttaccatttt ggcgatcatc
    53941 gtggcatgtg tgacgtggca ggtggctgca cgatttatat ttactagtcc cagtattttt
    54001 acagatgaac tcagccgttt gctctttatt tgtcttggac tttttggtgg ggcatacacc
    54061 gcagggcaaa accggcatct ggcgattgac ctgctaccta tgatgctgaa aggaaaagcc
    54121 cgacgtcatt tatttttgtg tattcagatt atcgttatta tcttcgcaac catcattatg
    54181 gtatatggtg gtgggctatt aacgatggat acattcgatt caggtcagac ctcgcccgct
    54241 ttaggctggc aaatgggata tatctatatg agcatcccga ttagtggtgt acttattatt
    54301 atatacacca tagatatggt tttaaccgaa cttaaacaac cactctaaag ataacaaaca
    54361 acaaccaacc atagtaggaa tggagaaatt atggattact ggttaccgat tattgtgtta
    54421 tttggtgcct tcttttttat gttggcatta ggtgtaccta ttgtttatgc cattggttta
    54481 tcgacactgg catcaatttc cacacaactc gatttcaact cagcattgag tgtggtttcc
    54541 caaaagttag cctccgggtt agatagtttt acgttgttgg caatcccatt ttttatcttg
    54601 tctggcaaca ttatgaacca tggaggaata gcgcgacgat taatcaactt tgcccgtatt
    54661 ctcggcggtc gtctgccagg ctcacttgcc cactgtaata ttctcgccaa tatgctgttc
    54721 ggggcaattt ctggttcagc cgtggcttcg gcggctgcga tgggcggcgt catgcatccg
    54781 caacaggtta aagagggtta cgacccggca ttcagtactg cggttaacgt tgcctctgcc
    54841 ccgacgggtt tgcttattcc accaagtaat acgttaatcg tctattcact ggtcagtggt
    54901 ggtacttcta ttgccgcact gttcctggcg ggttatgttc cgggaatttt gctgggtctg
    54961 gcactgatgg taatagccgg tattatcgcg gtacgtcgcg gttatccaaa gccagaacgc
    55021 ccgactttac gccaggctgg cgttgcgata tggatggcta tccccagtat tttcctgatt
    55081 attttaatta tggggggtgt attaagtggt atttttaccc cgacagaggc ctccgcaatt
    55141 gcagtaattt ataccctttt ccttgcactg gttctttatc gtgaaatctc agttaaagat
    55201 ttacctaaaa tatttctgga atccgttatt accactgcaa ttgtcttgtt attaattggt
    55261 tcttcgatgg gtatgtcatg ggcaatgtca aacgctgacg ttcccttcct gattctcgat
    55321 ttgcttaaca ctatttctga caacccaata ataatcctgc ttattatcaa tattatcctg
    55381 ttgattatcg gcacttttat ggatatgaca ccggcggtac tgatttttac gccgatattt
    55441 ttaccggttg tcaccgaact gggcatggac ccgattcact ttggtattgt catggtactg
    55501 aacatgtgta tcggtatttg tactccgcct gtaggcagtg tgttatttgt cggttgtagt
    55561 gtatctaaat taccgattaa taaaattatc aaacctatgc tgccattcta tgccgtgatg
    55621 gtattggtgc tggcaatggt gacctatatt ccgcaaatca gtatggcatt gccaagagca
    55681 ctgggctact gatgcgcatt cactggcggc acctgccgcc atatttatta gaaaaggaac
    55741 atctatgaaa ataaaagtat ccgctggcat tatcggtgct gttcttatgt tatccgcaag
    55801 ccagtcctgg gcagtgacat taaaactgag tcataatcag gataagtctc atcctgttca
    55861 taaagcgatg gagttctttg cgaaaaagag caaagagtac tctaacggtg atattactat
    55921 tcgtatttat ccaaatggaa cattgggtac tcaacgagaa acaatggagc tgattcgttc
    55981 tggcgctatt cccctggtaa aaaccaatgc ggcagaaatg gaagcatttg aaaattccta
    56041 taaattattt agcctgcctt atttgttccg cgatcgtgat cattattatc aggtcatgca
    56101 gggcgatatc gggagaaaaa tcctcgactc aacgaaaagc aggtgatg
//
LOCUS       DAPOAV010000020        53988 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.020, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000020 DAPOAV010000000
VERSION     DAPOAV010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 53988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53988
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.020"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(317..871)
                     /locus_tag="RN951_001460"
     CDS             complement(317..871)
                     /locus_tag="RN951_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001317283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HDX2526478.1"
                     /translation="MLGCCVQDIWGMTWKTTATLLLLVPVLQAPLARYAWIYRSILES
                     VALMLKNNYDNMRNEMNHFAKHVIITGGGSNSDLFMQIFADMFNLPARRNAINGCASL
                     GAAINKAVGLGLYPDYATAVDKMVRVKDIFIPIESNAKRYDAMNKGIFKDLTKHNDVI
                     LKKSYEVMHGELGNVDSIQSWSNA"
     gene            complement(911..1273)
                     /gene="queD"
                     /locus_tag="RN951_001461"
     CDS             complement(911..1273)
                     /gene="queD"
                     /locus_tag="RN951_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708563.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="HDX2526479.1"
                     /translation="MSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEV
                     DPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLL
                     SAVMVKETCTAGCIYRGE"
     gene            1592..3391
                     /gene="cysJ"
                     /locus_tag="RN951_001462"
     CDS             1592..3391
                     /gene="cysJ"
                     /locus_tag="RN951_001462"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent assimilatory sulfite reductase
                     flavoprotein subunit"
                     /protein_id="HDX2526480.1"
                     /translation="MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVL
                     NQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYK
                     FKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEF
                     FCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSV
                     ATGAVNEIHSSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDAL
                     GVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYAT
                     LTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIAS
                     SQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPAN
                     PETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKD
                     GVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQAL
                     LEVIAEFGGMDTEAADEFLSELRVERRYQRDVY"
     gene            3391..5103
                     /gene="cysI"
                     /locus_tag="RN951_001463"
     CDS             3391..5103
                     /gene="cysI"
                     /locus_tag="RN951_001463"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="assimilatory sulfite reductase (NADPH)
                     hemoprotein subunit"
                     /protein_id="HDX2526481.1"
                     /translation="MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGF
                     KGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKF
                     AGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSN
                     PYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKT
                     TVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGY
                     LPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPI
                     RPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGAFRI
                     TANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERF
                     LPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGN
                     RIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPAR
                     DLWD"
     gene            5177..5911
                     /gene="cysH"
                     /locus_tag="RN951_001464"
     CDS             5177..5911
                     /gene="cysH"
                     /locus_tag="RN951_001464"
                     /EC_number="1.8.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708560.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HDX2526482.1"
                     /translation="MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNL
                     PGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLK
                     VYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQ
                     SGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTT
                     RKWEPGMSEEETRFFGLKRECGLHEG"
     gene            6176..6328
                     /locus_tag="RN951_001465"
     CDS             6176..6328
                     /locus_tag="RN951_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HDX2526483.1"
                     /translation="MLTKYALVAIIVLCFTVLGFTLMVGDSLCELSIRERGMEFKAVL
                     AYESKK"
     gene            6523..9222
                     /locus_tag="RN951_001466"
     CDS             6523..9222
                     /locus_tag="RN951_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HDX2526484.1"
                     /translation="MRKYPLSLLKDKNIVTFFDFWGKTRRGEKDGGDDYHLLCWHSLD
                     VAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPP
                     ELKIQEGARKNYEKISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTT
                     GHHGRPPDRMDELDNFLPEDKAAARDFLLEIKPLFPLIEIPAFWDDDEGIELIKHLSW
                     YISATVVLADWTGSSTRFFPRVAHPMDIKGYWQKTLIQAQNALTVFPLKAKVAPFNGI
                     NTLFPFIENPTPLQQKVLDLDISQQGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQ
                     GLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLV
                     GSEEPDEQTFSQGCAAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNK
                     ILLADEIHACDAYMSCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQ
                     QEAPFLEKDDYPWLTHVTKSDVNSHRVATRKDVERSVSVGWLHSEQECIARIESAVSQ
                     GKCIAWIRNSVDDAIKVHRQLLARGVIPASSLSLFHSRFAFSDRQRIETETLARFGKY
                     CSLQRASQVIVCTQVIEQSVDIDLDEMISDLAPVDLLIQRAGRLQRHIRDINGQLKRD
                     GKDERSPPELLILAPVWDDSPGDEWFGSAMRNSAFVYPDHGRIWLTQRVLREQGAIQM
                     PHAARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFRPGYAANINDY
                     LPEKLSTRLAEESVSLWLATCIDGVVKPYATGAHAWEMSVVRVRRSWWKKHRDEFSLL
                     EGEAFRLWCIEQRQDPEMANVILVNDDESCGYSATEGLIGKVG"
     gene            9320..10882
                     /gene="casA"
                     /locus_tag="RN951_001467"
     CDS             9320..10882
                     /gene="casA"
                     /locus_tag="RN951_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cse1/CasA"
                     /protein_id="HDX2526485.1"
                     /translation="MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADL
                     QGAVWQFLLGLLQTSFAPKDHRRWDDIWEDGLEAEKLREALQSLEHAFQFGPASPSFM
                     QDFEALKGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEHVCPHCSALALFSLQLNA
                     PSGGKGYRTGLRGGGPMTTLIELQEYQGNQQTPLWRKLWPNVMPQDEADLPLPKKFDD
                     LVFPWLGPTRTSELAGAVVTHDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQSDA
                     LLSLMTTKNYGANYAMWQHPLTPYRIPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKS
                     ENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLKKKEGQIP
                     KLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIE
                     EGQDADELLGKWQKEIWLFARQDFDERVFTNPYEPVDLKRVMTARKKYFTTSAEKQSA
                     KAAREKKQEAAE"
     gene            10879..11415
                     /gene="casB"
                     /locus_tag="RN951_001468"
     CDS             10879..11415
                     /gene="casB"
                     /locus_tag="RN951_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cse2/CasB"
                     /protein_id="HDX2526486.1"
                     /translation="MSIVKEEHKATLRKWHEELQEKRGERASLRRSTTVNDVCLTDGF
                     RLFLKNRQIKWQDEPEWRITALALIAAVSANVKAIDERQPFAAQLAAVMSKGRFTRLS
                     AVKTPDELLRQLRRAVRLLNGSVNLDSLAEGVFRWCQESDDLLNHHRRQQRPTEFIRI
                     RWALEYYQAGDADNEQNQ"
     gene            11427..12482
                     /gene="cas7e"
                     /locus_tag="RN951_001469"
     CDS             11427..12482
                     /gene="cas7e"
                     /locus_tag="RN951_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein
                     Cas7/Cse4/CasC"
                     /protein_id="HDX2526487.1"
                     /translation="MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSL
                     KRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEEKKAIEWAAKIADYLGKAK
                     NDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLALLRKDRMAVD
                     IAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGE
                     TGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAY
                     ASWALAEKGTDQPRSLAAAFYEPINGTRQLEVAVQRITTLRENMNTVYEQKTDYASFD
                     VMNKQGSMKDVLDFICA"
     gene            12493..13239
                     /gene="cas5e"
                     /locus_tag="RN951_001470"
     CDS             12493..13239
                     /gene="cas5e"
                     /locus_tag="RN951_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cas5/CasD"
                     /protein_id="HDX2526488.1"
                     /translation="MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGV
                     GIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTVQMPKEVRKARYFSRREELSDPE
                     LLSAIISRRDYYTDAWWMVAVATTPDAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPL
                     APLLLEGNACDALCNAYQQYQDHFHKLKVSLPKLQDECWWEGKHDGLVASKILRRRDV
                     PLNRQQWLFGERTVNQGPWLSKEEPCTSQE"
     gene            13221..13871
                     /gene="cas6e"
                     /locus_tag="RN951_001471"
     CDS             13221..13871
                     /gene="cas6e"
                     /locus_tag="RN951_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein
                     Cas6/Cse3/CasE"
                     /protein_id="HDX2526489.1"
                     /translation="MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQ
                     FLYRREELQGAFRFFVLSQERPAESDTFTIECRSFAPELCTGQQLCFNLRANPTICKA
                     GKRHDLLMEAKRQVRGQAEGSDVWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQ
                     LRRENSRQLIQFSSVDYTGMLTVTDPGLFVQRLSQGYGKSRAFGCGLMLIKPGAEA"
     gene            13868..14788
                     /gene="cas1e"
                     /locus_tag="RN951_001472"
     CDS             13868..14788
                     /gene="cas1e"
                     /locus_tag="RN951_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated endonuclease Cas1"
                     /protein_id="HDX2526490.1"
                     /translation="MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHI
                     PVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQ
                     AKLALTEDLRLKVVRKMYELRFREPQPARRSVEQLRGIEGSRVRQTYALLAKQYGVKW
                     NGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYD
                     IADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGE
                     IEPPQPAPDMLPPAIPEPETLGDSGHRGRG"
     gene            14788..15081
                     /gene="cas2"
                     /locus_tag="RN951_001473"
     CDS             14788..15081
                     /gene="cas2"
                     /locus_tag="RN951_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated endoribonuclease
                     Cas2"
                     /protein_id="HDX2526491.1"
                     /translation="MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIW
                     QQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ"
     repeat_region   15178..15940
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=15178..15206
                     /rpt_unit_seq="gtgttccccgcgccagcggggataaaccg"
     gene            complement(15961..16998)
                     /gene="iap"
                     /locus_tag="RN951_001474"
     CDS             complement(15961..16998)
                     /gene="iap"
                     /locus_tag="RN951_001474"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase isozyme conversion
                     aminopeptidase"
                     /protein_id="HDX2526492.1"
                     /translation="MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFF
                     PGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIA
                     AHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKN
                     TPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGV
                     KTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSV
                     EATNWNLGNKDGYQQRAKTPAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIM
                     LPLVKELAKAS"
     gene            17250..18158
                     /gene="cysD"
                     /locus_tag="RN951_001475"
     CDS             17250..18158
                     /gene="cysD"
                     /locus_tag="RN951_001475"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="HDX2526493.1"
                     /translation="MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVML
                     HLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINP
                     FVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDP
                     KNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLE
                     RDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVST
                     TSERQGRVIDRDQAGSMELKKRQGYF"
     gene            18160..19587
                     /gene="cysN"
                     /locus_tag="RN951_001476"
     CDS             18160..19587
                     /gene="cysN"
                     /locus_tag="RN951_001476"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysN"
                     /protein_id="HDX2526494.1"
                     /translation="MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLI
                     GRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYF
                     STEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGI
                     KHLVVAINKMDLVDYSEETFTRIREDYLTFAEQLPGNLDIRFVPLSALEGDNVASQSE
                     SMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQ
                     RVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAV
                     QSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNG
                     IGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPKNEAAVASSEFSA
                     FELELNALVRRHFPHWGARDLLGDK"
     gene            19587..20192
                     /gene="cysC"
                     /locus_tag="RN951_001477"
     CDS             19587..20192
                     /gene="cysC"
                     /locus_tag="RN951_001477"
                     /EC_number="2.7.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyl-sulfate kinase"
                     /protein_id="HDX2526495.1"
                     /translation="MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTV
                     AGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLV
                     VLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFT
                     GIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS"
     gene            20242..20565
                     /locus_tag="RN951_001478"
     CDS             20242..20565
                     /locus_tag="RN951_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3561 family protein"
                     /protein_id="HDX2526496.1"
                     /translation="MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPML
                     IYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALF
                     MWLLG"
     gene            20759..21070
                     /gene="ftsB"
                     /locus_tag="RN951_001479"
     CDS             20759..21070
                     /gene="ftsB"
                     /locus_tag="RN951_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsB"
                     /protein_id="HDX2526497.1"
                     /translation="MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNA
                     KLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNN
                     R"
     gene            21089..21799
                     /gene="ispD"
                     /locus_tag="RN951_001480"
     CDS             21089..21799
                     /gene="ispD"
                     /locus_tag="RN951_001480"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HDX2526498.1"
                     /translation="MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHA
                     LLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWV
                     LVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGL
                     WHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPE
                     DLALAEFYLTRTIHQENT"
     gene            21799..22278
                     /gene="ispF"
                     /locus_tag="RN951_001481"
     CDS             21799..22278
                     /gene="ispF"
                     /locus_tag="RN951_001481"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HDX2526499.1"
                     /translation="MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHAL
                     TDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQA
                     PKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK"
     gene            22275..23324
                     /gene="truD"
                     /locus_tag="RN951_001482"
     CDS             22275..23324
                     /gene="truD"
                     /locus_tag="RN951_001482"
                     /EC_number="5.4.99.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(13) synthase TruD"
                     /protein_id="HDX2526500.1"
                     /translation="MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHI
                     LVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLS
                     AFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYF
                     GAQRFGIGGSNLQGAQRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQ
                     VVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQ
                     AAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVV
                     RELINTTGDYAHIAE"
     gene            23305..24066
                     /gene="surE"
                     /locus_tag="RN951_001483"
     CDS             23305..24066
                     /gene="surE"
                     /locus_tag="RN951_001483"
                     /EC_number="3.1.3.5"
                     /EC_number="3.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="HDX2526501.1"
                     /translation="MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNS
                     LTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVI
                     YSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINV
                     PDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVD
                     EGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW"
     gene            24060..24686
                     /gene="pcm"
                     /locus_tag="RN951_001484"
     CDS             24060..24686
                     /gene="pcm"
                     /locus_tag="RN951_001484"
                     /EC_number="2.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-L-isoaspartate O-methyltransferase"
                     /protein_id="HDX2526502.1"
                     /translation="MVSRRVQALLDQLRAQGIQDEQVLNALAAVPREKFVDEAFEQKA
                     WDNIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQHVCS
                     VERIKGLQWQARRRLKNLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMT
                     QLDEGGILVLPVGEEHQYLKRVRRRGGEFIIDTVEAVRFVPLVKGELA"
     gene            24826..25965
                     /gene="nlpD"
                     /locus_tag="RN951_001485"
     CDS             24826..25965
                     /gene="nlpD"
                     /locus_tag="RN951_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator NlpD"
                     /protein_id="HDX2526503.1"
                     /translation="MSAGSPKFTVRRIAALSLVSLWLAGCSDTSNPPAPVSSVNGNAP
                     ANTNSGMLITPPPKMGTTSTAQQPQIQPVQQPQIQATQQPQIQPVQPVAQQPVQMENG
                     RIVYNRQYGNIPKGSYSGSTYTVKKGDTLFYIAWITGNDFRDLAQRNNIQAPYALNVG
                     QTLQVGNASGTPITGGNAITQADAAEQGVVIKPAQNSTVAVASQPTITYSESSGEQSA
                     NKMLPNNKPAATTVTAPVTVPTASTTEPTVSSTSTSTPISTWRWPTEGKVIETFGASE
                     GGNKGIDIAGSKGQAIIATADGRVVYAGNALRGYGNLIIIKHNDDYLSAYAHNDTMLV
                     REQQEVKAGQKIATMGSTGTSSTRLHFEIRYKGKSVNPLRYLPQR"
     gene            26028..27020
                     /gene="rpoS"
                     /locus_tag="RN951_001486"
     CDS             26028..27020
                     /gene="rpoS"
                     /locus_tag="RN951_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoS"
                     /protein_id="HDX2526504.1"
                     /translation="MSQNTLKVHDLNEDAEFDENGVEVFDEKALVEEEPSDNDLAEEE
                     LLSQGATQRVLDATQLYLGEIGYSPLLTAEEEVYFARRALRGDVASRRRMIESNLRLV
                     VKIARRYGNRGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMN
                     QTRTIRLPIHIVKELNVYLRTARELSHKLDHEPSAEEIAEQLDKPVDDVSRMLRLNER
                     ITSVDTPLGGDSEKALLDILADEKENGPEDTTQDDDMKQSIVKWLFELNAKQREVLAR
                     RFGLLGYEAATLEDVGREIGLTRERVRQIQVEGLRRLREILQTQGLNIEALFRE"
     gene            complement(27141..27548)
                     /locus_tag="RN951_001487"
     CDS             complement(27141..27548)
                     /locus_tag="RN951_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001208089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDX2526505.1"
                     /translation="MALRNKAFHQLRQLFQQHTARWQHELPDLTKPQYAVMRAIADKP
                     GIEQVALIEAAVSTKATLAEMLARMENRGLVRREHDPADKRRRFVWLTAEGEKILAAA
                     IPIGDSVDEEFLGRLSGEEQELFMQLVRKMMNA"
     gene            27695..28288
                     /locus_tag="RN951_001488"
     CDS             27695..28288
                     /locus_tag="RN951_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HDX2526506.1"
                     /translation="MKLIVGMTGATGAPLGVALLQALREMPNVETHLVMSKWAKTTIE
                     LETPYSARDVAALADFSHNPADQAAIISSGSFRTDGMIVIPCSMKTLAGIRAGYADGL
                     VGRAADVVLKEGRKLVLVPREMPLSTIHLENMLALSRMGVAMVPPMPAFYNHPETVDD
                     IVHHVVARVLDQFGLEHPHARRWQGLPQARNFSQENE"
     gene            28288..29714
                     /locus_tag="RN951_001489"
                     /pseudo
     CDS             28288..29714
                     /locus_tag="RN951_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311619.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
     gene            29725..29961
                     /locus_tag="RN951_001490"
     CDS             29725..29961
                     /locus_tag="RN951_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526507.1"
                     /translation="MICPRCADEQIEVMAKSPVKDVWTVYQCQHCLYTWRDTEPLRRT
                     SREHYPEAFRMTQKDIDDAPMVPSIPPLLVEGKR"
     gene            complement(30000..31364)
                     /locus_tag="RN951_001491"
     CDS             complement(30000..31364)
                     /locus_tag="RN951_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family transporter"
                     /protein_id="HDX2526508.1"
                     /translation="MSTITLLCIALAGVIMLLLLVIKAKVQPFVALLLVSLLVALAAG
                     IPAGEVGKVMIAGMGGVLGSVTIIIGLGAMLGRMIEHSGGAESLANYFSRKLGDKRTI
                     AALTLAAFFLGIPVFFDVGFIILAPIIYGFAKVAKISPLKFGLPVAGIMLTVHVAVPP
                     HPGPVAAAGLLHADIGWLTIIGIAISIPVGIVGYFAAKIINKHQYAMSVEVLEQMQLA
                     PASEEGATKLSDKINPPGVALVTSLIVIPIAIIMAGTVSATLMPPSHPLLGTLQLIGS
                     PMVALMIALVLAFWLLALRRGWSLQHTSDIMGSALPTAAVVILVTGAGGVFGKVLVES
                     GVGKALANMLQMIDLPLLPAAFIISLALRASQGSATVAILTTGGLLSEAVMGLNPIQC
                     VLVTLAACFGGLGASHINDSGFWIVTKYLGLSVADGLKTWTVLTTILGFTGFLITWCV
                     WAVI"
     gene            complement(31453..32229)
                     /locus_tag="RN951_001492"
     CDS             complement(31453..32229)
                     /locus_tag="RN951_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HDX2526509.1"
                     /translation="MPRFAANLSMMFTEVPFIERFAAARKAGFDAVEFLFPYDYSTLQ
                     IQKQLEQNHLTLALFNTAPGDINAGEWGLSALPGREHEAHADIDLALEYALALNCEQV
                     HVMAGVVPAGEDAERYRAVFIDNLRYAADRFAPHGKRILVEALSPGVKPHYLFSSQYQ
                     ALAIVEEVARDNVFIQLDTFHAQKVDGNLTHLIRDYAGKYAHVQIAGLPDRHEPDDGE
                     INYPWLFRLFDEVGYQGWIGCEYKPRGLTEEGLGWFDAWR"
     gene            complement(32234..32872)
                     /locus_tag="RN951_001493"
     CDS             complement(32234..32872)
                     /locus_tag="RN951_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HDX2526510.1"
                     /translation="MSDFAKVEQSLREEMTRIASSFFQRGYATGSAGNLSLLLPDGNL
                     LATPTGSCLGNLDPQRLSKVAADGEWLSGDKPSKEVLFHLALYRNNPRCKAVVHLHST
                     WSTALSCLQGLDSSNVIRPFTPYVVMRMGNVPLVPYYRPGDKRIAQDLAELAADNQAF
                     LLANHGPVVCGESLQEAANNMEELEETAKLIFILGDRPIRYLTAGEIAELRS"
     gene            complement(32869..34131)
                     /locus_tag="RN951_001494"
     CDS             complement(32869..34131)
                     /locus_tag="RN951_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001649192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxo-tetronate kinase"
                     /protein_id="HDX2526511.1"
                     /translation="MIKIGVIADDFTGATDIASFLVENGLPTVQINGVPTGKMPEAID
                     ALVISLKTRSCPVVEATQQSLAALSWLQQQGCKQIYFKYCSTFDSTAKGNIGPVTDAL
                     MDALDTPFTVFSPALPVNGRTVYQGYLFVMNQLLAESGMRHHPVNPMTDSYLPRLVEA
                     QSTGRCGVVSAHVFEQGVDAVRQELARLQQEGYRYAVLDALTEHHLEIQGEALRDAPL
                     VTGGSGLAIGLARQWAQENGNQAREAGHPLAGRGVVLSGSCSQMTNRQVAHYRQIAPA
                     REVDVARCLSTETLAAYAHELAEWVLGQESVLAPLVFATASTDALAAIQQQYGAQKAS
                     QAVETLFSQLAARLAAEGVTRFIVAGGETSGVVTQSLGIKGFHIGPTISPGVPWVNAL
                     DKPVSLALKSGNFGDEAFFSRAQREFLS"
     gene            complement(34128..35036)
                     /locus_tag="RN951_001495"
     CDS             complement(34128..35036)
                     /locus_tag="RN951_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDX2526512.1"
                     /translation="MKTGSEFHVGIVGLGSMGMGAALSCVRAGLSTWGADLNSNACAT
                     LKEAGACGVSDNAATFAEKLDALLVLVVNAAQVKQVLFGETGVAQHLKPGTAVMVSST
                     IASADAQEIATALAGFDLEMLDAPVSGGAVKAANGEMTVMASGSDIAFERLAPVLEAV
                     AGKVYRIGAEPGLGSTVKIIHQLLAGVHIAAGAEAMALAARAGIPLDVMYDVVTNAAG
                     NSWMFENRMRHVVDGDYTPHSAVDIFVKDLGLVADTAKALHFPLPLASTALNMFTSAS
                     NAGYGKEDDSAVIKIFSGITLPGAKS"
     gene            35232..35999
                     /locus_tag="RN951_001496"
     CDS             35232..35999
                     /locus_tag="RN951_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417215.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDX2526513.1"
                     /translation="MIPVERRQIILEMVAEKGIVSIAELTDRMNVSHMTIRRDLQKLE
                     QQGAVVLVSGGVQSPGRVAHEPSHQVKTALAMTQKAAIGKLAASLVQPGSCIYLDAGT
                     TTLAIAQHLIHMESLTVVTNDFVIANYLLDNSNCTIIHTGGAVCRENRSCVGEAAATM
                     LRSLMIDQAFISASSWSVRGISTPAEDKVTVKRAIASASRQRVLVCDATKYGQVATWL
                     ALPLSEFDQIITDDGLPESASRALAKQDLSLLVAKNE"
     gene            complement(36050..36706)
                     /gene="pphB"
                     /locus_tag="RN951_001497"
     CDS             complement(36050..36706)
                     /gene="pphB"
                     /locus_tag="RN951_001497"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HDX2526514.1"
                     /translation="MPSTRYQKINAHHYRHIWVVGDIHGEYQLLQSRLHQLSFCPETD
                     LLISVGDNIDRGPESLDVLRLLNQPWFISVKGNHEAMALDAFATGDGNVWLASGGDWF
                     FDLNDSEQKEATDLLLKFHHLPHIIEITNDNIKYVIAHADYPGSEYLFGKEIAESELL
                     WPVDRVQKSLNGELQQINGADYFIFGHMMFDNIQTFANQIYIDTGSPKSGRLSFYKIK
                     "
     gene            complement(36812..39373)
                     /gene="mutS"
                     /locus_tag="RN951_001498"
     CDS             complement(36812..39373)
                     /gene="mutS"
                     /locus_tag="RN951_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDX2526515.1"
                     /translation="MSAIENFDAHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDA
                     KRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATS
                     KGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEP
                     ADRETMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFG
                     TRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRN
                     LEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDF
                     TAELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRAQLETVDSAPVQA
                     LREKMGEFAELRDLLERAIIDTPPVLVRDGGVIASGYNEELDEWRALADGATDYLERL
                     EVRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAPINYMRRQTLKNAERYIIPELKE
                     YEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAERAYTLN
                     YTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYM
                     RQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILH
                     NATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKME
                     GVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELES
                     ISPNATATQVDGTQMSLLSVPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV"
     gene            39449..39583
                     /locus_tag="RN951_001499"
     CDS             39449..39583
                     /locus_tag="RN951_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526516.1"
                     /translation="MIPELIISGEEANGEFLMLVPGKMLFCSFCVMLMKQVRKIASVE
                     "
     gene            39660..40013
                     /locus_tag="RN951_001500"
     CDS             39660..40013
                     /locus_tag="RN951_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrous oxide-stimulated promoter family
                     protein"
                     /protein_id="HDX2526517.1"
                     /translation="MSGKRISREKLTIKKMIDLYQAKCPQASAEPEHYEALFVYAQKR
                     LDKCVFGEEKPACKQCPVHCYQPAKREEMKQIMRWAGPRMLWRHPILTVRHLIDDKRP
                     VPELPEKYRPKKPRE"
     gene            complement(40050..42128)
                     /gene="flhA"
                     /locus_tag="RN951_001501"
     CDS             complement(40050..42128)
                     /gene="flhA"
                     /locus_tag="RN951_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase transcriptional activator
                     FlhA"
                     /protein_id="HDX2526518.1"
                     /translation="MSYTPMSDLGQQGLFDITRTLLQQPDLASLCEALSQLVKRSALA
                     DNAAIVLWQAQTQRASYYASREKDTPIKYEDETVLAHGPVRSILSRPDTLHCSYEEFC
                     ETWPQLAAGGLYPKFGHYCLMPLAAEGHIFGGCEFIRYDDRPWSEKEFNRLQTFTQIV
                     SVVTEQIQSRVVNNVDYELLCRERDNFRILVAITNAVLSRLDMDELVSEVAKEIHYYF
                     DIDDISIVLRSHRKNKLNIYSTHYLDKQHPAHEQSEVDEAGTLTERVFKSKEMLLINL
                     HERDDLAPYERMLFDTWGNQIQTLCLLPLMSGDTMLGVLKLAQCEEKVFTTTNLNLLR
                     QIAERVAIAVDNALAYQEIHRLKERLVDENLALTEQLNNVDSEFGEIIGRSEAMYSVL
                     KQVEMVAQSDSTVLILGETGTGKELIARAIHNLSGRNNRRMVKMNCAAMPAGLLESDL
                     FGHERGAFTGASAQRIGRFELADKSSLFLDEVGDMPLELQPKLLRVLQEQEFERLGSN
                     KIIQTDVRLIAATNRDLKKMVADREFRSDLYYRLNVFPIHLPPLRERPEDIPLLAKAF
                     TFKIARRLGRNIDSIPAETLRTLSNMEWPGNVRELENVIERAVLLTRGNVLQLSLPDI
                     VLPEPETPPAATVVAQEGEDEYQLIVRVLKETNGVVAGPKGAAQRLGLKRTTLLSRMK
                     RLGIDKSALI"
     gene            complement(42202..43212)
                     /gene="hypE"
                     /locus_tag="RN951_001502"
     CDS             complement(42202..43212)
                     /gene="hypE"
                     /locus_tag="RN951_001502"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417210.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation carbamoyl dehydratase
                     HypE"
                     /protein_id="HDX2526519.1"
                     /translation="MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLELA
                     QLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEE
                     GLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAADKLFINTAGMGAIPANIHWG
                     AQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKA
                     LRDATRGGVNAVVHEFAAACGCGIEISEAALPVKPAVRGVCELLGLDALNFANEGKLV
                     IAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR
                     IC"
     gene            complement(43209..44330)
                     /gene="hypD"
                     /locus_tag="RN951_001503"
     CDS             complement(43209..44330)
                     /gene="hypD"
                     /locus_tag="RN951_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase formation protein HypD"
                     /protein_id="HDX2526520.1"
                     /translation="MRFVDEYRAPEQVMQLIEHLRERASHLSYTAERPLRIMEVCGGH
                     THAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRIDTCVEIASHPEVIFCTFGDAMRV
                     PGKQGSLLQAKARGADVRIVYSPMDALKLAQENPTRKVVFFGLGFETTMPTTAITLQQ
                     AKARDVQNFYFFCQHITLIPTLRSLLEQPDNGIDAFLAPGHVSMVIGTDAYNFIASDF
                     HRPLVVAGFEPLDLLQGVVMLVEQKIAAHSKVENQYRRVVPDAGNLLAQQAIADVFCV
                     NGDSEWRGLGVIESSGVHLTPDYQRFDAEAHFRPAPQQVCDDPRARCGEVLTGKCKPH
                     QCPLFGNTCNPQTAFGALMVSSEGACAAWYQYRQQESEA"
     gene            complement(44330..44602)
                     /gene="hypC"
                     /locus_tag="RN951_001504"
     CDS             complement(44330..44602)
                     /gene="hypC"
                     /locus_tag="RN951_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 3 maturation protein HypC"
                     /protein_id="HDX2526521.1"
                     /translation="MCIGVPGQIRTIDGNQAKVDVCGIQRDVDLTLVGSCDENGQPRV
                     GQWVLVHVGFAMSVINEAEARDTLDALQNMFDVEPDVGALLYGEEK"
     gene            complement(44593..45465)
                     /gene="hypB"
                     /locus_tag="RN951_001505"
     CDS             complement(44593..45465)
                     /gene="hypB"
                     /locus_tag="RN951_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase nickel incorporation protein HypB"
                     /protein_id="HDX2526522.1"
                     /translation="MCTTCGCGEGNLYIEGDEHNPHSAFRSAPFAPAARPKMKITGIK
                     APEFTPSQTEEGDLHYGHGEAGTHAPGMSQRRMLEVEIDVLDKNNRLAERNRARFAAR
                     KQLVLNLVSSPGSGKTTLLTETLMRLKDSVPCAVIEGDQQTVNDAARIRATGTPAIQV
                     NTGKGCHLDAQMIADAAPRLPLDDNGILFIENVGNLVCPASFDLGEKHKVAVLSVTEG
                     EDKPLKYPHMFAAASLMLLNKVDLLPYLNFDVEKCIACAREVNPEIEIILISATSGEG
                     IDQWLNWLETQRCA"
     gene            complement(45469..45819)
                     /gene="hypA"
                     /locus_tag="RN951_001506"
     CDS             complement(45469..45819)
                     /gene="hypA"
                     /locus_tag="RN951_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HDX2526523.1"
                     /translation="MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSL
                     AFCFDLVCRGSVAEGCKLHLEEQEAECWCETCQQYVTLLTQRVRRCPQCHGDMLQIVA
                     DDGLQIRRIEIDQE"
     gene            46031..46492
                     /gene="hycA"
                     /locus_tag="RN951_001507"
     CDS             46031..46492
                     /gene="hycA"
                     /locus_tag="RN951_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase regulator HycA"
                     /protein_id="HDX2526524.1"
                     /translation="MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHH
                     AMSCAPDKELCFVLFEHFRIYVTLADGFNSHTIEYYVETKDGEDKQRIAQAQLSIDGM
                     IDGKVNIRDREQVLEHYLEKIAGVYDSLYTAIENNVPVNLSQLVKGQSPAA"
     gene            46617..47228
                     /gene="hycB"
                     /locus_tag="RN951_001508"
     CDS             46617..47228
                     /gene="hycB"
                     /locus_tag="RN951_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycB"
                     /protein_id="HDX2526525.1"
                     /translation="MNRFVIADSTLCIGCHTCEAACSETHRQHGLQSMPRLRVMLNEK
                     ESAPQLCHHCEDAPCAVVCPVNAITRVDGAVQLNESLCVSCKLCGIACPFGAIEFSGS
                     RPLDIPANANTPKAPPAPPAPARISTLLDWVPGIRAIAVKCDLCSFDEQGPACVRMCP
                     TKALHLVDNTDIARVSKRKRELTFNTDFGDLTLFQQAQSGEAK"
     gene            47225..49051
                     /gene="hycC"
                     /locus_tag="RN951_001509"
     CDS             47225..49051
                     /gene="hycC"
                     /locus_tag="RN951_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit 3"
                     /protein_id="HDX2526526.1"
                     /translation="MSAISLINSGVAWFIAAAVLAFLFSFQKTLSGWIAGIGGAVGSL
                     YTAAAGFTVLTGAVGVSGALSLVSYDVQISPLNAIWLITLGLCGLFVSLYNIDWHRHA
                     QVKCNGLQINMLMAAAVCAVIASNLGMFVVMAEVMALCAVFLTSNSKEGKLWFALGRL
                     GTLLLAIACWLLWQRYGTLDLRLLDMRMQQLPLGSDIWLLGVIGFGLLAGIIPLHGWV
                     PQAHANASAPAAALFSTVVMKIGLLGILTLSLLGGNAPLWWGIALLVLGMITAFVGGL
                     YALMEHNIQRLLAYHTLENIGIILLGLGAGVTGIALEQPALIALGLVGGLYHLLNHSL
                     FKSVLFLGAGSVWFRTGHRDIEKLGGIGKKMPVISIAMLVGLMAMAALPPLNGFAGEW
                     VIYQSFFKLSNSGAFVARLLGPLLAVGLAITGALAVMCMAKVYGVTFLGAPRTKEAEN
                     ATCAPLLMSVSVVALAICCVIGGVAAPWLLPMLSAAVPLPLEPANTTVSQPMITLLLI
                     ACPLLPFIIMAICKGDRLPSRSRGAAWVCGYDHEKSMVITAHGFAMPVKQAFAPVLKL
                     RKWLNPVSLVPGWQCEGSALLFRRMALVELAVLVVIIVSRGA"
     gene            49054..49977
                     /gene="hycD"
                     /locus_tag="RN951_001510"
     CDS             49054..49977
                     /gene="hycD"
                     /locus_tag="RN951_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycD"
                     /protein_id="HDX2526527.1"
                     /translation="MSVLYPLIQALVLFAVAPLLSGITRVARARLHNRRGPGVLQEYR
                     DIIKLLGRQSVGPDASGWVFRLTPYVMVGVMLTIATALPVVTVGSPLPQLGDLITLLY
                     LFAIARFFFAISGLDTGSPFTAIGASREAMLGVLVEPMLLLGLWVAAQVAGSTNISNI
                     TDTVYHWPLSQSIPLVLALCACAFATFIEMGKLPFDLAEAEQELQEGPLSEYSGSGFG
                     VMKWGISLKQLVVLQMFVGVFIPWGQMETFTAGGLLLALVIAIVKLVVGVLVIALFEN
                     SMARLRLDITPRITWAGFGFAFLAFVSLLAA"
     gene            49995..51704
                     /gene="hycE"
                     /locus_tag="RN951_001511"
     CDS             49995..51704
                     /gene="hycE"
                     /locus_tag="RN951_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycE"
                     /protein_id="HDX2526528.1"
                     /translation="MSEEKLGQHYLAALNEAFPGVVLDHAWQTKDQLTVTVKVNYLPE
                     VVEFLYYKQGGWLSVLFGNDERKLNGHYAVYYVLSMEKGTKCWVTVRVEVDANKPEYP
                     SVTPRVPAAVWGEREVRDMYGLIPVGLPDERRLVLPDDWPDELYPLRKDSMDYRQRPA
                     PTTDAETYEFINELGDKKNNVVPIGPLHVTSDEPGHFRLFVDGENIIDADYRLFYVHR
                     GMEKLAETRMGYNEVTFLSDRVCGICGFAHSTAYTTSVENAMGIQVPERAQMIRAILL
                     EVERLHSHLLNLGLACHFTGFDSGFMQFFRVRETSMKMAEILTGARKTYGLNLIGGIR
                     RDLLKDDMIQTRQLAQQMRREVQELVDVLLSTPNMEHRTVGIGRLDPEIARDFSNVGP
                     MVRASGHARDTRADHPFVGYGLLPMEVHSEQGCDVISRLKVRINEVYTALNMIDYGLD
                     NLPGGPLMVEGFTYIPHRFALGFAEAPRGDDIHWSMTGDNQKLYRWRCRAATYANWPT
                     LRYMLRGNTVSDAPLIIGSLDPCYSCTDRMTVVDVRKKKSKVVPYKELERYSIERKNS
                     PLK"
     gene            51714..52256
                     /gene="hycF"
                     /locus_tag="RN951_001512"
     CDS             51714..52256
                     /gene="hycF"
                     /locus_tag="RN951_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycF"
                     /protein_id="HDX2526529.1"
                     /translation="MFTFIKKVIKTGTATSSYPLEPIAVDKNFRGKPEQNPQQCIGCA
                     ACVNACPSNALTVETDLATGELAWEFNLGRCIFCGRCEEVCPTAAIKLSQEYELAVWK
                     KEDFLQQSRFALCNCRVCNRPFAVQKEIDYAIALLKHNGDSRAENHRESFETCPECKR
                     QKCLVPSDRIELTRHMKEAI"
     gene            52256..53023
                     /gene="hycG"
                     /locus_tag="RN951_001513"
     CDS             52256..53023
                     /gene="hycG"
                     /locus_tag="RN951_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycG"
                     /protein_id="HDX2526530.1"
                     /translation="MSNLLGPRDANGIPVPMTVDESIASMKASLLKKIKRSAYVYRVD
                     CGGCNGCEIEIFATLSPLFDAERFGIKVVPSPRHADILLFTGAVTRAMRSPALRAWQS
                     APDPKICISYGACGNSGGIFHDLYCVWGGTDKIVPVDVYIPGCPPTPAATLYGFAMAL
                     GLLEQKIHARGPGEQDEQPAEILHGDMVQPLRVKVDREARRLAGYRYGRQIADDFLTQ
                     LGQGEEQVARWLEAENDPRLNEIVSHLNHVVEEARIR"
     gene            53020..53430
                     /gene="hycH"
                     /locus_tag="RN951_001514"
     CDS             53020..53430
                     /gene="hycH"
                     /locus_tag="RN951_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase assembly protein HycH"
                     /protein_id="HDX2526531.1"
                     /translation="MSEKVVFSQLSRKFIDENDATPAEAQQVVYYSLAIGHHLGVIDC
                     LEAALTCPWDEYLAWIATLEAGSEARRKMEGVPKYGEIVIDINHVPMLANAFDKARVA
                     QTSQQQEWSTMLLSMLHDIHQENAIYLMVRRLRD"
     gene            53423..53893
                     /gene="hycI"
                     /locus_tag="RN951_001515"
     CDS             53423..53893
                     /gene="hycI"
                     /locus_tag="RN951_001515"
                     /EC_number="3.4.23.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation peptidase HycI"
                     /protein_id="HDX2526532.1"
                     /translation="MTDVLLCVGNSMMGDDGAGPLLAEKCAAAPKGNWVVIDGGSAPE
                     NDIVAIRELRPTRLLIVDATDMGLNPGEIRIIDPDDIAEMFMMTTHNMPLNYLIDQLK
                     EDIGEVIFLGIQPDIVGFYYPMTQPIKDAVETVYQRLEGWEGNGGFAQLAVEEE"
BASE COUNT        12681 a        13878 c        14713 g        12716 t
ORIGIN      
        1 tttacattac cgtttctata cgctgttgat gaatagttct tatgaataaa gatatccagt
       61 tcatacttta agtgaaaatt gataaagtgc gattcgtatt gtcttttatt ctaaagacat
      121 cgagtgtagt taatattcct tgtaaaaaca gggataaacc gaactagtta aagtttttat
      181 tatgttccct gcatcagcgg ggataaaccg gacttgttat cattttttaa gttgtcgaac
      241 ttatgttccc cgcgtcagcg gggataacca ttcaggtatg ttcaggccgg gcagtttccc
      301 gcccggcctt cctcacttac gcattcgacc agctctggat cgaatccaca ttccccaatt
      361 ccccatgcat cacttcatac gattttttca gtattacatc attatgtttg gttaggtctt
      421 tgaaaatgcc tttattcatc gcgtcgtagc gtttggcatt gctctcaatc ggtataaaga
      481 tatctttcac gcgaaccatt ttgtcgacag ccgttgcgta atccgggtat agtcccagac
      541 ctaccgcctt attaatcgct gcccccagac ttgcacaacc gttaatggcg ttacgtcgtg
      601 ccggaaggtt gaacatgtcg gcaaaaatct gcataaacag atcgctgttc gaaccgccgc
      661 cagtaatgat cacatgcttt gcaaagtgat tcatttcatt acgcatattg tcgtaattgt
      721 tcttcagcat cagagccacg ctttccagta tcgaacgata tatccatgcg taacgcgcaa
      781 gcggtgcctg caataccggc accaataata ataatgtcgc agtcgtcttc catgtcatgc
      841 cccagatatc ctgaacacaa caccctaaca tagcgttact taagggaaat tgaccgccga
      901 cacactctta tcattcgccg cgatagatac aaccagcggt gcaggtttct tttaccatca
      961 ccgcacttaa cagcggcaca acgggtttaa cctgatccca aatccatttt gctaaaactt
     1021 cgctggttgg gttttccaga cctggaatat cattgagata atggtgatcg aggcgctcat
     1081 aagttggctt aaacgccgct ttcagttcag cgaaatcgat aatccagccc gtatgcggat
     1141 cgacttcccc ggtaatttcc agtcgcacca taaaggaatg cccgtgcagg cgaccacatt
     1201 tatgcccttc cgggacgtgt ggtaagcggt gagcggcttc gaaggtgaaa tctttaaata
     1261 acgtggtgga catcataatt tctctacagg acgataaaac cgccgtagag taccggaaag
     1321 gctgtttttt cgcattatct aaaacgactt tgttgcgcaa aatcgctgat ttatcttaat
     1381 gattggctaa attcatttgt ttttcattag gttggttaat ctattttgtt gttaaagact
     1441 attgctaaaa caggttagtc gatttggtta ttagttatcg ctatcccgtc tttaatccac
     1501 accgttcacc ccgttaacct taccttctct tctgttttat gggcgctgac agggcgcaga
     1561 aacagctttg cttactggaa cataacgacg catgacgaca caggtcccac cttccgcgtt
     1621 gcttccgttg aacccggagc aactggcacg ccttcaggcg gccacgaccg atttaacgcc
     1681 tacccagctt gcctgggttt ctggctattt ctggggcgta ctcaatcagc agcctgctgc
     1741 gcttgcagcg acgccagcgc cagccgcaga aatgccgggt ataactatta tctccgcctc
     1801 gcaaaccggc aatgcgcgcc gggttgctga agcattacgc gatgatttat tagcagcaaa
     1861 actgaacgtt aagctggtga acgcgggcga ctataaattc aaacaaatcg ccagcgaaaa
     1921 actgcttatc gtggtgacgt caacgcaagg agaaggggaa ccgccggaag aagccgtcgc
     1981 gctgcataag ttcctgttct ccaaaaaagc gccgaagctg gaaaacaccg catttgccgt
     2041 gtttagcctc ggcgatagct cttatgaatt tttctgccag tccgggaaag attttgacag
     2101 caagctggcg gaactgggcg gtgaacgcct gctcgaccgt gtcgatgccg atgttgaata
     2161 ccaggctgct gccagcgagt ggcgcgcccg cgtggttgat gcgcttaaat cgcgtgcgcc
     2221 tgtcgcggca ccttcgcaat ccgtcgctac tggcgcggta aatgaaatcc actccagccc
     2281 gtacagcaaa gacgctccgc tggtggcgag cctttcggtt aaccagaaaa ttaccggacg
     2341 taactctgaa aaagacgttc gccatatcga aattgactta ggtgactcgg gcctgcgtta
     2401 ccagccgggt gacgcgctgg gcgtctggta tcagaacgat ccggcactgg tgaaagaact
     2461 tgtcgaactg ctgtggctga aaggcgatga acctgtcacc gtcgagggca aaacgttgcc
     2521 tctgaacgaa gcgctacagt ggcacttcga actgaccgtc aacaccgcca acattgttga
     2581 gaattacgcc acgcttaccc gcagcgaaac actgctgccg ctggtgggcg ataaagcgaa
     2641 gttacagcat tacgccgcga cgacgccgat tgtcgacatg gtgcgtttct ctccggcgca
     2701 actggatgcc gaagcgctga ttaatctgct gcgcccgctg accccgcgcc tgtattccat
     2761 cgcctcctcg caggcggaag tcgagaacga agtacacgtc accgttggtg tggtgcgtta
     2821 cgacgtggaa ggccgagccc gtgccggtgg tgcctccagc ttcctcgcgg atcgcgtgga
     2881 agaagagggc gaagtccgcg tatttatcga acataacgat aactttcgcc tgcccgctaa
     2941 cccggaaacc ccggtgatta tgattggccc aggcaccggt attgcgccgt tccgcgcctt
     3001 tatgcagcaa cgcgccgccg acgaagcgcc aggtaaaaac tggctgttct ttggtaatcc
     3061 gcactttacg gaagacttcc tgtaccaggt ggagtggcag cgctacgtca aagatggcgt
     3121 gctgacacgt atcgatcttg cctggtcgcg cgaccaaaaa gaaaaagttt acgtacaaga
     3181 caaactgcgc gaacagggcg cggagctgtg gcgctggatc aatgatggtg cccacattta
     3241 tgtctgcggc gacgctaatc gcatggcgaa agacgttgag caggcacttc tggaagtgat
     3301 tgccgaattt ggtggcatgg acaccgaagc ggcggatgaa tttttaagtg agctgcgcgt
     3361 agagcgccgt tatcagcgag atgtctacta atgagcgaaa aacatccagg gcctttagtg
     3421 gtcgaaggaa aactgacaga cgccgagcgc atgaagcttg aaagcaacta cctgcgcggc
     3481 accattgcgg aagatttaaa cgacggtctg accggcggct ttaagggcga taacttcctg
     3541 ctgatccgct tccacggcat gtatcagcag gatgaccgcg acatccgcgc cgaacgtgct
     3601 gaacagaagc tggagccgcg ccacgcgatg ctgcttcgct gtcgtctgcc gggtggggtg
     3661 attaccacta aacagtggca ggcgatcgac aaatttgccg gtgaaaacac catctatggc
     3721 agcattcgcc tgaccaaccg ccagacgttt cagttccacg gcattctgaa aaagaacgtc
     3781 aaaccggtgc accagatgct gcactcggtc ggtcttgatg cgctggcgac agctaacgac
     3841 atgaaccgta acgtactctg cacctcgaac ccttacgagt cgcagctgca cgcggaagcg
     3901 tacgagtggg cgaagaagat ttctgagcat ctgttgcctc gtacccgcgc gtatgcggag
     3961 atctggctcg accaggaaaa agtcgccact actgatgaag aaccgatcct tggtcagacc
     4021 tacctgccgc gtaagttcaa aaccacggta gtgatcccgc cgcagaacga tatcgatctg
     4081 catgccaacg acatgaactt cgtggcaatc gccgaaaacg gcaagctggt aggcttcaac
     4141 ctgctggtgg gcggtgggct ttctatcgaa cacggcaaca agaaaaccta cgcccgcacg
     4201 gcgagcgagt ttggctattt gccgctggag catacgctgg cggtggccga agccgtcgtg
     4261 acaactcagc gtgactgggg taaccgaacc gatcgtaaaa atgccaaaac caaatacacg
     4321 ctggagcgcg tgggggttga gacgtttaaa gcggaagtgg agcgtcgcgc ggggatcaaa
     4381 tttgaaccga tccgtccata tgagttcacc ggacgaggcg atcgtattgg ctgggttaag
     4441 ggcattgatg ataactggca cctgacgctg tttatcgaaa atggtcgcat ccttgattat
     4501 ccggggcgtc cgctgaaaac cggcctgctg gagatcgcga agatccacaa aggcgctttc
     4561 cgcattacgg cgaaccagaa tctgatcatc gccggtgtac cggaaagcga gaaagcgaag
     4621 atcgagaaga tcgccaaaga gagcggttta atgaatgccg tcacgccgca gcgtgaaaac
     4681 tcgatggcct gcgtgtcatt cccgacttgc ccgctggcga tggcggaagc agagcgtttc
     4741 ctgccgtctt ttatcgacaa catcgataat ttaatggcga aacatggtgt cagcgatgag
     4801 catatcgtga tgcgtgtaac aggctgcccg aacggttgtg gtcgcgcgat gctggcggaa
     4861 gtgggcctgg tgggtaaagc gccgggtcgc tacaacctgc atcttggcgg caaccgcatt
     4921 gggacacgta tcccacggat gtataaagaa aacatcaccg agccggaaat cctggcgtcg
     4981 cttgatgaac tgatagggcg ctgggcgaaa gagcgcgaag cgggtgaagg cttcggcgac
     5041 tttacggtgc gtgcgggcat cattcgcccg gtgctcgatc cggcgcgcga tttgtgggat
     5101 taaccatcag cccggtcttg taggcctgat aagacgcgtg agcgtcgcat caggcaaggc
     5161 aaacagtgag gaatctatgt ccaaactcga tctaaacgcc ctgaacgaac tgccgaaggt
     5221 agatcgcatt ctggcgctgg cagaaactaa cgccgaactg gaaaaactgg acgctgaagg
     5281 ccgcgttgcc tgggcgctgg ataatctgcc cggtgaatat gtactttctt ccagctttgg
     5341 cattcaggcg gcggtgagcc tgcatctggt gaatcagatt cacccggata ttccggtgat
     5401 cctcaccgac accggctatc tgttcccgga aacctaccgc tttattgacg agttaacgga
     5461 caaactcaag ctcaacctga aagtgtaccg cgctaccgaa agcgccgcct ggcaggaagc
     5521 acgctacggc aaactgtggg aacagggcgt tgaaggcatt gaaaagtaca atgacatcaa
     5581 caaagtcgaa ccgatgaacc gggcgctgaa agaactgaat gcgcaaacgt ggtttgctgg
     5641 cctgcgccgc gaacaatccg gcagccgcgc caatttaccg gtgctggcaa ttcagcgtgg
     5701 cgtatttaaa gtgctgccga ttatcgactg ggataaccga actatttatc agtacctgca
     5761 aaaacatggc ctgaaatatc acccattatg ggatgaagga tatttatcgg tcggtgatac
     5821 ccatacaacc cgtaaatggg aacctggcat gtcggaagaa gaaacacgtt tctttggctt
     5881 aaaaagggaa tgtggattgc acgaagggta aatattgccg gataaattaa acgcctctgt
     5941 cagaaatgat gggggcgttt ttattttgcg agcagtattc ctgattttaa acgtgaacgc
     6001 cgctggaaga attatcaggt atagaatggc gtcgggtgct tgaggctgtc tggcgttaag
     6061 cattcgcgag gttccagatg gacaaaagcc ccaggcgata tttctatcaa cctgaggctt
     6121 acgttcgaac ccaaacaatt cgaatgttag tctcttcttt gcagggaggc aagacatgct
     6181 gacaaaatat gcccttgtgg caatcatagt gctgtgtttt acagtactgg gattcacgct
     6241 gatggtaggc gactcgttgt gtgagttgag tatcagagaa cgtggtatgg agtttaaggc
     6301 agttctcgct tacgaatcga agaagtagcc accacgcggg ggtaaaaccc cgcgtactga
     6361 attgtgatgg tttggtctcc tgcacccttt tttaatttat attgtttatg tgaatattat
     6421 gcctatgttt attattcata tatattacgg atgaaaatta tttgattatt cataatgtaa
     6481 atattttatt gaatgatata tatcacagat aatttttaat atatgcgtaa atatccttta
     6541 agtttactga aggataaaaa tattgtgact ttttttgatt tctggggaaa aacccgacgc
     6601 ggcgagaaag acgggggcga cgactatcac cttctttgct ggcattcgct ggatgtagcc
     6661 gcgatgggct atttaatggt taaaagaaat tgcttcgggc tggctgatta ttttcgtcaa
     6721 ttagggattt ctgacaagga acaggcggct caatttttcg cctggttgct gtgctggcac
     6781 gatattggaa aatttgcccg ctcttttcaa caactttacc tgccccctga actcaagatt
     6841 caggaaggtg ccagaaaaaa ttacgaaaaa atctctcatt caacgctggg ctactggttg
     6901 tggaatcatt atttaagtga atgtcaggag ttacttcctt catcttcgct ctctccgcgc
     6961 aaacttaggc gagtgataga aatgtggatg cccgtgacga cagggcatca tggtcggccc
     7021 cctgatcgta tggatgaatt ggataatttt ctgcctgaag acaaagctgc agcacgagat
     7081 tttctccttg aaatcaaacc actgtttccg ctcatagaga tccccgcatt ctgggatgat
     7141 gatgagggca ttgaacttat aaaacacctt tcctggtata tctctgcaac cgtcgtgctc
     7201 gcagactgga cgggttcgtc aacgcgattt tttccacgcg tcgcacaccc aatggatatt
     7261 aaaggttact ggcagaaaac tttaattcag gctcaaaacg ccttaaccgt ctttcctcta
     7321 aaagcaaaag tcgcgccttt caacggaatt aatacgctgt ttccttttat tgagaatccg
     7381 acaccgttac agcaaaaggt gctggatctg gatatcagcc agcaaggacc gcagttattt
     7441 attctggaag atgtgactgg cgcaggtaaa acagaagcgg cgcttatcct ggcgcacagg
     7501 ttgatagctg cggggaaagc tcaggggctg ttttttggtc tgccaacaat ggcaacggcc
     7561 aatgccatgt acgatcggct ggtcaaaacc tggcttgctt tctattcgcc agaatcccgc
     7621 cccagcctgg tgctggcaca tagtgcccgc acattaatgg accgctttaa tgaatcactc
     7681 tggtctggtg atttagtcgg gtcagaagaa ccggatgaac aaacgttcag tcagggatgt
     7741 gcggcctggt ttgccgacag taacaagaag gcgttgctgg ctgaaattgg cgtcggcacg
     7801 ctggatcagg cgatgatggc ggtgatgccg ttcaaacata ataatctgcg gcttctgggg
     7861 ctgagtaaca aaatcctgct ggctgatgag atccacgcct gtgacgctta catgtcgtgc
     7921 attcttgaag ggttgatcga gcggcaggcg cgtggcggaa acagcgttat tttgctttct
     7981 gccacgttat ctcaacagca gcgcgacaaa ctcgtcgctg cctttgcgcg gggtacagag
     8041 ggccagcaag aagctccgtt cctggaaaag gatgattacc cctggctgac gcatgtcacg
     8101 aaatccgatg tgaactcaca ccgggtagcg acgcgcaaag acgttgagcg tagcgtcagc
     8161 gtgggttggc ttcatagtga acaagagtgt attgcgcgta tcgaatcggc ggtaagtcag
     8221 gggaaatgca tcgcctggat ccggaattct gtcgatgacg ctattaaggt tcatcgtcag
     8281 ctgcttgccc gcggcgtcat tcctgcttcc agcctttcac tttttcatag ccgctttgct
     8341 tttagcgatc gccagcgaat tgaaacggag acactggcac gctttggtaa atattgtagt
     8401 ttacagagag cgtcgcaagt cattgtttgt acacaagtaa ttgagcaaag cgtggatatt
     8461 gacctggacg aaatgatctc cgacctggcc cctgttgatt tgctgattca gcgagcagga
     8521 cgattacagc ggcatatccg cgatattaat ggtcagttaa agcgtgacgg aaaggacgag
     8581 cgttcccccc ctgaattgct gattctggct cccgtctggg acgactctcc tggcgacgaa
     8641 tggtttggca gtgccatgcg taacagtgca tttgtctatc ccgatcatgg gcgaatctgg
     8701 ctgacgcagc gtgtgctgcg tgagcaaggt gctattcaga tgccacacgc agcccggctt
     8761 cttattgaat ccgtctacgg tgaggacgtg gtaatgccgg aaggatttgc ccgcagcgag
     8821 caggagcaag tgggcaaata ttactgcgat cgcgcaatgg ctaaaaagtt tgtgctgaac
     8881 ttcaggcccg gctatgccgc caatatcaac gattacctcc cggaaaaact gtcgacacgt
     8941 ctggctgagg agtctgtttc cctgtggctg gctacctgta ttgacggtgt ggtgaagcct
     9001 tatgccaccg gtgctcacgc atgggaaatg agcgttgtca gagtgcgccg aagctggtgg
     9061 aaaaaacatc gggatgagtt ttctttactg gagggagagg cgttcaggct gtggtgcatt
     9121 gaacagcgac aagatccgga gatggcaaac gtgattttag tcaacgatga cgaaagttgc
     9181 gggtattcgg ctacggaagg attgattggc aaggttggtt gagatgtctg cgacaggact
     9241 ctctgaatag ttgatacacc gaaaaggatg gaaagatgga caaccgacct gggatggtct
     9301 tttttacgag aggatgcgta tgaactcgtt ttcacttctg acaaccccgt ggttgcctgt
     9361 tcgttttaaa gacggaacga caggcaagct ggcaccagtc gatctggctg atgaaaatgt
     9421 tgtcgatatc gctgcgccgc gggcagatct ccagggtgcg gtatggcagt ttttgctggg
     9481 gctactacaa accagcttcg cgccaaaaga tcatcgtcgt tgggatgata tctgggaaga
     9541 cggactggaa gctgaaaagc tacgggaagc attgcagtca ttagaacatg ctttccagtt
     9601 tgggccagct tccccttcat ttatgcagga tttcgaggcg ctcaagggag ataaagttca
     9661 ggtcgcttcg ctactgcctg agattcccgg cgctcaaaca acgaagttta ataaagacca
     9721 ctttattaag cgtggcgtga ctgaacacgt atgccctcat tgttccgcgt tagctctgtt
     9781 ctccctacag ttaaatgcgc catcaggcgg caaaggctat cgcaccggtt tgcgcggcgg
     9841 tgggccgatg accactctga ttgaattaca ggaatatcaa ggcaatcaac aaacgccctt
     9901 gtggcgcaaa ctgtggccca atgtgatgcc gcaggatgaa gccgacttac cgctacccaa
     9961 aaaatttgac gatctggttt tcccctggct tggcccgacg cgaaccagcg aactggccgg
    10021 tgcggtggta acccatgatc aggtcaataa actccaggct tactggggaa tgccgcgccg
    10081 tattcgtatt gattttaata ccacgacagt cggcaactgc gatatttgcg gtgaacagag
    10141 cgacgcgctc ctgagcctga tgacgaccaa aaattacggt gcgaattatg ccatgtggca
    10201 gcatccctta acgccttacc gtataccact taaagagggt ggcgagtttt actcggtcaa
    10261 accacaaccg ggcggtttaa tctggcgcga ctggttaggc cttatcgaaa cgggtaaatc
    10321 agaaaacaat acggaacttc ccgcgctggt ggtgaaactc tttaatgcca gcagtctgaa
    10381 acaggcaaaa gtaggcctgt ggggatttgg ctatgatttc gacaacatga aagcgcgctg
    10441 ttggtacgaa caccatttcc cgctgctgct caagaaaaaa gaaggccaga taccgaaact
    10501 gcgtctggct gcgcaaacgg cttcacggat tctaagtctg ttacgaagtg cattgaaaga
    10561 agcgtggttc tccgatccaa aaggtgcacg gggtgatttc agttttgtgg atatcgactt
    10621 ctggaacaaa actcagcatc gcttcctgag gttagtgcgc caaattgaag aaggtcagga
    10681 tgcggacgaa ttactcggca aatggcaaaa ggaaatttgg ttattcgcgc gtcaggattt
    10741 tgacgagcgt gtattcacca atccatatga gcctgttgat ttgaaacgcg ttatgaccgc
    10801 gcgcaagaaa tatttcacaa catcggcgga gaagcaaagt gctaaagccg ccagggagaa
    10861 aaagcaggag gctgctgaat gagtattgta aaagaggagc acaaagccac gctgcgcaaa
    10921 tggcacgagg aattgcagga gaaacgtggc gaacgtgcca gtctgcggcg tagtacgacg
    10981 gttaatgatg tttgtctgac ggatggattt cgcctgtttc tgaagaacag acaaataaag
    11041 tggcaggatg aacctgagtg gcgtatcacc gcactggcgc tgatagccgc agttagcgcc
    11101 aatgttaaag ctattgatga acggcagcct tttgccgcgc agctggcggc ggtaatgtca
    11161 aaggggcgtt ttactcgtct gtcggcagta aaaacaccgg atgaattact gcgccagtta
    11221 cgccgcgcag tcagattatt aaacggttcc gtcaatcttg actctctggc agagggggtc
    11281 ttccgttggt gccaggagag cgacgacctg ctcaatcatc accgccgcca gcagcggcca
    11341 accgaattta tccgtatccg ctgggcgctg gaatattacc aggctggcga cgccgataac
    11401 gaacaaaatc aataaaggac tatctcatga caacatttat tcagcttcat ttgttaaccg
    11461 cttaccctgc tgccaacctt aaccgtgatg ataccggtgc gccaaaaact gtggtgctgg
    11521 gtggagcaac gcgtctgcgc gtttcctcgc aaagtctgaa acgtgcgtgg cgcacttctg
    11581 cactttttga acaggcactg gcgggccata ttggtattcg cagtgggcgt attgcgcgtg
    11641 aggcggcaac tatcctgatt gagaaaggaa tcgaagagaa aaaagccatc gaatgggcgg
    11701 caaaaattgc agattatctt gggaaagcta aaaacgacaa aaaaccaaaa gatccgctca
    11761 ctaacgccga aactgaacag ttagtccata tcagcccggc agaatttgac gccgtaaaag
    11821 cgctggccca tcagcttgca gaagaaaagc gcgcgccaaa agaggaagat ctcgcgttgt
    11881 tacgcaaaga ccgtatggcg gtagatattg ccatgtttgg tcgtatgctg gcgaataaac
    11941 ccgagtttaa tgttgaagcc gcctgccagg tagcgcacgc atttggtgtc agtgaaacga
    12001 ttgtcgaaga tgattttttc accgccgttg atgatttgcg ccaggcttca gaagatgccg
    12061 gtgccgggca tcttggtgaa accggattcg gttctgcact gttctacacc tatatctgca
    12121 ttgataaaga tctgctggtc gaaaaccttg gcggtgacga agcgttagct aatcagacca
    12181 tacgtgcctt tacggaagcc gcacttaaag tctccccaac cggcaaacag aacagctttg
    12241 ccagccgtgc ctacgcctcc tgggcgctgg cagaaaaagg caccgatcaa ccgcgttctc
    12301 tggcggcagc tttctatgaa cccattaatg gcacccgtca gttagaggtg gcggtgcagc
    12361 gtattacaac tcttcgcgaa aatatgaata cggtctacga acagaagacc gattacgcaa
    12421 gttttgacgt gatgaacaaa cagggaagca tgaaggacgt gctggacttt atctgcgcgt
    12481 aaggggcggc ttatgagcca atatctgatt tttcagcttc atgggccgat ggcatcctgg
    12541 ggcgtcgatg cccccggcga agtgcgtcat acccatgaac tgccttcgcg ctcagcattg
    12601 ctggggctgc tggctgccgg ggtagggatc cggcgtgatg ataccgaacg cttaaacgcg
    12661 tttaatcgcc actattcact ggtggtttgc gccagccgta acccgcgctg ggcacgggat
    12721 tatcacacgg tccagatgcc aaaagaggtg cgtaaagcac gttatttcag ccgtcgcgaa
    12781 gagttgagcg accctgagct tttgagcgcg attatctccc ggcgcgacta ctacaccgat
    12841 gcctggtgga tggtggcggt ggcaacaacc cccgatgcgc cttacagcct cgaacagttg
    12901 caggacggtt tacgccatcc ggtttttccg ctttatctgg ggcgaaaaag tcatccgctg
    12961 gcgttaccac ttgcgccgtt actgctcgaa ggcaacgcgt gtgatgcctt atgtaatgca
    13021 taccaacagt atcaggatca tttccataaa ctgaaagtct cactcccgaa acttcaggat
    13081 gaatgctggt gggaagggaa acacgacggc ctggtcgcga gcaaaatatt acgccgccgg
    13141 gatgttcctt taaatcgtca gcagtggctg tttggggaac gcaccgtcaa tcaggggccg
    13201 tggctcagca aggaggaacc atgtacctct caagaataac cttacatacc ggccagcttt
    13261 cgcctgcgca gttgctgcat ctggtggatc gcggtgaata tgtgatgcat cagtggctgt
    13321 gggatctctt ccctggcggc aaagaaaggc aatttcttta tcgtcgggaa gaactccagg
    13381 gcgcgtttcg cttttttgta ctgtcgcagg aacgcccggc ggaaagtgat acgttcacca
    13441 tagaatgccg gtcatttgcg cccgagctgt gtaccggaca acaactttgt ttcaacctgc
    13501 gggcgaatcc aacaatctgt aaagcgggca agcgccacga tctgctgatg gaggcgaaac
    13561 ggcaggtgag ggggcaggcg gaaggaagtg atgtctggtt gcatcaacaa caggcggcgc
    13621 tggactggct ggcagcgcag ggggagagaa gcggttttac actgctggat acctcggttg
    13681 atgcctaccg acaacagcaa ctgcggcggg aaaactcccg gcaactgatc cagttcagta
    13741 gcgtggatta tacggggatg cttacggtca ccgatcctgg gttatttgtg caacgcctga
    13801 gccaggggta tggtaaaagc cgggcgttcg gctgtggtct gatgctgatc aaacccggag
    13861 cagaggcgtg acgtttgtac cactgagccc gatcccatta aaagatcgca cctccatgat
    13921 cttcctccag tacggtcaga tcgacgtact ggacggcgct ttcgtgctga tcgacaaaac
    13981 agggatccga acgcatattc cggtgggatc ggtcgcctgc attatgctcg aaccaggaac
    14041 gagagtttcc cacgcggcgg tgcatctggc cgccacggtg ggaacactgc tggtctgggt
    14101 cggtgaagcg ggcgttcgcg tttactcctc cggacaaccc ggtggggcgc gggcagataa
    14161 attactctac caggcaaagc tggctttaac ggaagatcta cggttgaagg tggtgcgcaa
    14221 aatgtatgaa ttacgttttc gtgaaccaca gccagctcgc cgttcagtgg agcagttacg
    14281 tggaattgag ggatctcgcg ttcgccagac gtatgcatta ctggcgaaac aatatggtgt
    14341 gaaatggaat ggtcgcaaat acgatcctaa agactgggaa aaaggcgatg ttgtgaatcg
    14401 ctgcatcagt gctgctacat catgtctgta cggtatatct gaagcggcag tattagccgc
    14461 gggatatgcg cccgctattg ggtttatcca tagtggcaaa ccgctttcat ttgtttatga
    14521 catagccgat atcattaaat ttgattcggt tgtgccaaag gcatttgaaa tagcagcgag
    14581 gcaacccgca gaacctgata aagaagtcag attagcctgt cgcgatattt tccgtagcac
    14641 taagttaacg ggcaaattaa taccgttaat tgaggaagtc cttgccgcag gtgaaattga
    14701 accgccacaa cctgcgccgg atatgttacc gccagccatc cccgaacctg aaacgttggg
    14761 cgatagcggt catcgaggac gcggctgatg agcatggtcg tggttgttac agaaaatgtc
    14821 ccgccgcgct tacgtggacg gctcgcaatc tggctactgg aagtgcgtgc cggtgtgtat
    14881 gttggtgata catcaaaacg tattcgggag atgatctggc agcaaattac ccaactggct
    14941 ggttgcggaa atgtggtgat ggcctgggcg accaataccg agtcgggttt tgaatttcag
    15001 acctggggag aaaacagacg tattccggtg gatttggatg ggttacgttt ggtttctttt
    15061 cttcctgttg ataatcaata agttatccgt tctttaaaaa taaggaaatg ttttaattta
    15121 gttggtagat tgttgatgcg gaataaattt gtttaaaaac agttatgtat gcttagtgtg
    15181 ttccccgcgc cagcggggat aaaccggcat tcaatattcg gtttttaact gcggattcgt
    15241 gttccccgcg ccagcgggga taaaccgaac ccgcgccgtc ggctataaca tctctgaaag
    15301 tgttccccgc gccagcgggg ataaaccgat ttttgcggta ttctcccagc cgcccagcag
    15361 gtgttccccg cgccagcggg gataaaccga cgaccaaatg atctacgcgt attgccacct
    15421 cgtgttcccc gcgccagcgg ggataaaccg ccccgcacac gtaaaggcgt cggcatggat
    15481 gcgtgttccc cgcgccagcg gggataaacc cccagcgcca gacgggaaca caattttaaa
    15541 gccgtgttcc ccgcgccagc ggggataaac cgttgtcggg gatctgttca aactgactca
    15601 ttaggtgttc cccgcgccag cggggataaa ccgggggcgc attaacagag agaaaaacgc
    15661 ataggccgtg ttccccgcgc cagcggggat aaaccgcagc tcgcagcgct cggaacgtgg
    15721 cgctataggt gttccccgcg ccagcgggga taaaccgtcg ctattgccgg tagtgtcgct
    15781 gatagactcg tgttccccgc gccagcgggg ataaaccgcg gctatggaat ttatggagaa
    15841 gtttggtttt gtgttccccg cgtcagcggg gataaaccgg gcgcactgga tgcgatgatg
    15901 gatatcactt agaattcccc gcccttgcgg tagaactccc agctcccatt ttcaaaccca
    15961 tcaagacgcc ttcgccagct ccttcaccag cggtagcatt atccgcataa catcacggca
    16021 gcgacgttct attcttccag gaagtgcctt atcaatatgt tgttgattat ccagtcttac
    16081 gtcatgccag ctatttcccg ccgggaaggc aggtgttttt gcgcgttgct gataaccatc
    16141 cttattccca agattccagt tagtcgcttc caccgaaagt acagcaatgc ccgctttgtc
    16201 gaatatttct gcgtcattac aacacccagt gcctttcgga taatttttat tcaaacccgg
    16261 attggtcgtt gcggcaattc catgactacg cgcaattgcc agcgccctgt cgcgcgttaa
    16321 tttccttact gcttcagggg tttttacacc gctgttgaaa tacaatttat cgccaacaat
    16381 taagttatcg agattaatca ccagcagcgt atttttcttt tcggtgtcac tcatccgctt
    16441 gagtaaattc tctgcgccta atttcccttc ctcttcgccg ctggtcgcca caaatcgaat
    16501 accatactcg gtaggcgtat ttttcaggcg ttctgccaat tccagcatga cacctaaacc
    16561 tgcggcgtta tcatccattc cttgtaacgt aagcccgccg agattggcat cggcgtcagc
    16621 atcgctcagc ggggcgtaag tatccagatg cgccataatg atgatctgct gcggcgcttt
    16681 gccttcatga gcggcaatca ccgtacttcc cgtcacgtta tgccagctct tgcgattatc
    16741 gcgggcggta taaatatacc gactattaaa tgtccgaata tcactgcgat aacccatttg
    16801 ctgaaactgt tggcgaatat aatcggcaga taacatttct gcaggagttc cggtcatgcg
    16861 tcccggaaag aaagtagcaa tatgtcgtgc ctgagtatta gcaaaatcgc caggtttagg
    16921 tgacgaggcg tgtacgggga gaataaagca tacgccgagc gccagggcag cggtacggtg
    16981 gcgcaatgcg gaaaacatag tgagtcctta aataccatgc aaattttttt accgccatag
    17041 tatgaaactg ccgctgcgct aaaacaattt caaatcttcc taaacgcccg aaatccggtg
    17101 ccttaagcac tttttgatat tagctttgcc aaatcgttat tccgttaagg aactactcat
    17161 tctaattggt aatttcattc gttctcttac gctccctata gtcgaaacat ctgatggcaa
    17221 gaaaatagcg gtattgcaaa ggaacggtta tggatcaaat acgacttact cacctgcggc
    17281 aactggaggc ggaaagcatc cacattattc gcgaggtggc ggcagaattc tcaaatccgg
    17341 tgatgctcta ctctatcggt aaagattcca gcgtcatgct gcatctggcg cgcaaggcgt
    17401 tttatccagg tacgctgcct ttcccgttgc tgcatgtcga taccggctgg aaattccgcg
    17461 agatgtatga gttccgcgat cgtactgcta aagcctacgg ctgcgaactg ctggtgcata
    17521 aaaacccgga aggcgtggcg atggggatta atccattcgt gcacggcagc gcgaaacata
    17581 ccgatattat gaaaactgaa ggcctgaaac aggcgctgaa caaatacggt tttgatgccg
    17641 ccttcggtgg tgcgcgccgt gacgaagaga aatcccgcgc taaagagcga atttactctt
    17701 tccgtgaccg cttccatcgc tgggatccga aaaatcagcg cccggagctg tggcacaact
    17761 acaacgggca aattaacaaa ggcgaaagca tccgcgtctt cccgctctct aactggaccg
    17821 agcaggatat ctggcaatac atctggctgg aaaatatcga cattgttccg ctatatctcg
    17881 ctgcggaacg tccggttctg gaacgcgacg gtatgttgat gatgattgat gacaaccgta
    17941 tcgacctgca accgggcgaa gtgattaaaa aacggatggt gcgtttccgt acgctgggct
    18001 gctggccgct gaccggtgcg gtggagtcaa atgcacaaac actgccggaa atcatcgaag
    18061 agatgctggt ttccaccacc agtgaacgtc agggccgcgt gattgaccgc gaccaggcgg
    18121 ggtctatgga gctgaaaaaa cgtcaggggt atttttaaga tgaacaccgc acttgcacaa
    18181 caaatcgcca atgaaggcgg cgtcgaagcc tggatgattg cgcaacaaca taaaagcctg
    18241 ctgcgttttc tgacctgtgg tagcgtcgat gacggcaaaa gtaccctgat tggtcgcctg
    18301 ctgcacgata cccgccaaat ctacgaagat cagctctcat cgctgcataa cgacagtaag
    18361 cgtcacggca cccagggcga aaaactggat ctggctctgc tggtggacgg cctgcaagct
    18421 gagcgcgaac agggcatcac tattgatgtg gcctaccgct atttctctac cgagaagcgt
    18481 aaatttatta tcgccgacac ccccgggcac gagcagtata cccgcaatat ggcgaccggc
    18541 gcctcaacgt gtgagctggc gatcttactg atcgatgccc gtaaaggcgt gctcgatcaa
    18601 acccgtcgtc acagttttat ctccacgctg ctggggatca aacatctggt cgtagcgatc
    18661 aacaaaatgg atctggtgga ttacagtgaa gagacattca cccgcattcg tgaagactac
    18721 ctgactttcg ccgaacagtt acctggtaat ctggatatcc gctttgtgcc gctctctgca
    18781 ctggaaggcg acaacgtggc ttcgcaaagt gaaagtatgc cgtggtacag cggtccaaca
    18841 ctactcgaag tgctggaaac cgtggagatc cagcgagtgg tggatgccca gccaatgcgc
    18901 ttcccggtgc agtatgttaa ccgcccgaat ctcgattttc gtggttacgc cggaacgctg
    18961 gcatccggtc gcgtggaagt cgggcaacgt gtaaaagtgc tgccctctgg tgtggaatca
    19021 aacgtcgcgc ggatcgtgac ttttgatggt gatcgcgaag aagcctttgc cggagaagcg
    19081 atcaccctgg tgctgacgga tgagatcgac atcagccgtg gcgatctgct gctggcggca
    19141 gacgaagcgt taccggcggt gcagagcgcg tcggtggatg tggtatggat ggcggaacag
    19201 ccgctttctc cagggcagag ttacgacatc aaaattgccg gtaagaagac gcgcgcgcgt
    19261 gttgatggca ttcgctatca ggttgatatt aataacctta cccagcgtga agttgaaaac
    19321 ctgccactga atgggatcgg cctcgtggat ctcacttttg acgagccgct ggtgttagat
    19381 cgttatcaac aaaatccggt gacgggtggg ctgattttta tcgatcgcct gagcaacgtg
    19441 actgttggtg ccggtatggt gcatgagccg aaaaacgagg ccgccgttgc gtcatctgaa
    19501 ttcagtgcat tcgaactgga attgaatgct ctggttcgtc gccactttcc gcactggggc
    19561 gcgcgcgatt tgctggggga taaataatgg cgctgcatga cgaaaacgtc gtctggcata
    19621 gccatccggt cactgtgcaa caacgcgagc tacaccacgg tcatcgtggt gtagtgctgt
    19681 ggtttaccgg cctctccggg tccggtaaat caacggtcgc cggggcgctg gaggaggcgt
    19741 tacataaact cggcgtcagt acgtatctgc tggatggcga taatgttcgc cacggattat
    19801 gcagcgatct cggttttagc gatgccgatc gtaaagagaa tatccgtcgc gtcggtgaag
    19861 tggcgaattt gatggttgaa gccggactgg tagtgctgac cgcatttatc tcgccacacc
    19921 gcgccgaacg ccagatggtt cgcgaacgcg taggagaagg gcgctttatc gaagtgtttg
    19981 tcgatacgcc gctggcgatt tgcgaagccc gcgatccaaa aggcttatat aagaaagcgc
    20041 gtgccggtga actgcgcaac tttacgggaa tagattctgt ttacgaagcg cctgaatcgg
    20101 cagaaattca tctcaatggt gaacaattag taacaaattt ggtacagcaa ttattagatc
    20161 tgttgagaca gaacgatatt atcagatcct gagacaccac cgggtttcca tgcccggttc
    20221 gtcaaagtaa caggatcaaa tatgcgtaat agccataaca ttacactaac aaataacgac
    20281 agccttactg aggatgaaga aaccacatgg tcactgcctg gtgccgtggt cggttttatc
    20341 tcctggttat ttgcgctggc gatgccgatg ttgatttatg gctctaacac gctgttcttc
    20401 tttatctaca cctggccttt ctttctggcg ctgatgcccg tcgcggtagt ggtggggatt
    20461 gcgctgcatt cattgatgga cggaaagcta cgctacagta ttgttttcac cctggtgaca
    20521 gtaggcatta tgtttggcgc actgtttatg tggctactgg gctaatttgt actttcccgt
    20581 ctcctctgtt cataattcaa accgtaacta ataatgagat tatgttctgc acgccctggg
    20641 tatacgtaac aatggacaaa tgtggtacat ttgcccgcgt tgtcgcggta tccccaacag
    20701 aggatgtaga gtcgtcttcg gatgcatggg atgatgatgc cgtttttcag ggggcaggat
    20761 gggtaaacta acgctgctgt tgctggctat tctggtctgg ctacagtatt cgctgtggtt
    20821 cggtaagaac ggtatacatg actatacccg cgtcaatgat gatgtggcgg cacagcaagc
    20881 tacaaacgcg aaacttaaag cgcgaaacga tcaacttttt gccgaaattg acgatctcaa
    20941 tggcggccag gaggcgctcg aagagcgtgc gcgtaatgaa ctcagcatga ccaggccggg
    21001 cgaaactttt tatcgtctgg tgcctgacgc gtcgaagcgc gcacagtctg cggggcaaaa
    21061 caatcgataa atcagcccgg gaattaacat ggcaaccact catttggatg tttgcgccgt
    21121 ggttccggcg gccggatttg gccgtcgaat gcaaacggaa tgtcctaagc aatatctctc
    21181 aatcggtaat caaaccattc ttgaacactc ggtgcatgcg ctgctggcgc atccccgggt
    21241 gaaacgtgtc gtcattgcca taagtcctgg cgatagccgt tttgcacaac ttcctctggc
    21301 gaatcatccg caaatcaccg ttgtagatgg cggtgatgag cgtgccgatt ccgtgctggc
    21361 aggtttgaaa gccgctggcg acgcgcagtg ggtattggtg catgacgccg ctcgtccttg
    21421 tctgcatcag gatgacctcg cgcgattgtt ggcgttgagc gaaaccagcc gcacgggagg
    21481 gatcctagcc gcaccagtgc gcgatacgat gaaacgtgcc gaaccgggca aaaatgccat
    21541 tgctcatacc gttgatcgca acggcttatg gcacgcgctg acgccgcaat ttttccctcg
    21601 tgagctgtta catgactgtc tgacgcgcgc tctaaatgaa ggcgcgacta ttaccgacga
    21661 agcctcggcg ctggaatatt gcggattcca tcctcagttg gtcgaaggcc gtgcggataa
    21721 cattaaagtc acgcgcccgg aagatttggc actggccgag ttttacctca cccgaaccat
    21781 ccatcaggag aatacataat gcgaattgga cacggttttg acgtacatgc ctttggcggt
    21841 gaaggcccaa ttatcattgg tggcgtacgc attccttacg aaaaaggatt gctggcgcat
    21901 tctgatggcg acgtggcgct ccatgcgttg accgatgcat tgcttggcgc ggcggcgctg
    21961 ggggatatcg gcaagctgtt cccggatacc gatccggcat ttaaaggtgc cgacagccgc
    22021 gagctgctac gcgaagcctg gcgtcgtatt caggcaaagg gttataccct gggcaacgtc
    22081 gatgtcacta tcatcgctca ggcaccgaag atgttgccgc acattccaca aatgcgcgtg
    22141 tttattgccg aagatctcgg ctgccatatg gatgatgtta acgtgaaagc cactactacg
    22201 gaaaaacttg gatttaccgg acgtggggaa gggattgcct gtgaagcggt ggcgctactc
    22261 attaaggcaa caaaatgatt gagtttgata atctcactta cctccacggt aaaccgcaag
    22321 gcaccgggct gctgaaagcc aatccggaag actttgtggt ggtggaagat ttgggctttg
    22381 agcctgatgg tgaaggtgag catattctgg ttagaatcct caaaaacggc tgcaataccc
    22441 gttttgtggc ggatgcactg gcgaaattcc tgaaaattca tgcccgtgaa gtcagcttcg
    22501 ctgggcaaaa agacaaacat gctgttacgg aacagtggtt atgcgctcgc gtgccaggca
    22561 aggaaatgcc cgatctgagc gcctttcaac tggaaggctg ccaggtgctg gagtatgcgc
    22621 ggcacaagcg caagctgcgt ttaggcgcgc tgaaaggtaa cgcctttacc ctggttctgc
    22681 gcgaagtgag caatcgcgat gacgttgaac aacgtctgat cgatatttgc gtaaaaggtg
    22741 taccgaacta cttcggtgcc caacgttttg ggattggcgg tagcaacttg cagggggcgc
    22801 agcgctgggc gcaaaccaat actccggtgc gcgatcgcaa taaacggagt ttttggttgt
    22861 cggcagcccg cagtgcgttg tttaatcaga ttgttgctga gcgcctcaaa aaagcagacg
    22921 ttaatcaagt tgttgacggc gatgcgctac aattagccgg acgtggtagc tggtttgtcg
    22981 caaccaccga agaactggcg gaattacagc gtcgcgtcaa cgataaagag ctgatgataa
    23041 ccgccgcatt gccgggcagt ggcgaatggg gaactcagcg tgaagcgctg gcattcgaac
    23101 aagcagctgt cgccgcagaa actgaattac aagctttact ggtgcgcgaa aaagttgaag
    23161 ccgcgcgcag agcgatgctg ctgtatccgc aacaattaag ctggaattgg tgggatgacg
    23221 tcaccgtaga gatccgtttc tggcttccgg cgggtagttt tgcaaccagc gttgtcaggg
    23281 aacttatcaa cacaacaggt gattatgcgc atattgctga gtaatgatga cggggtacat
    23341 gcacccggta tacaaacgct ggcgaaagcc ttgcgtgagt ttgctgacgt tcaggtggtc
    23401 gcccccgatc gtaaccgcag cggcgcttca aattctctga cactggaatc ctccctgcgc
    23461 acgtttacct ttgaaaatgg tgatattgct gtgcaaatgg gaaccccgac cgattgcgtc
    23521 tatcttggcg tgaatgctct gatgcgtccg cgcccggaca ttgttgtgtc cggaattaac
    23581 gccgggccga atctggggga tgatgttatt tattccggta cggtagccgc cgcgatggaa
    23641 ggccgtcatt taggttttcc ggcgcttgcc gtctcgcttg acgggcataa acattacgac
    23701 actgccgcgg cggtaacctg ttcaattttg cgcgcactgt gtaaagagcc gttgcgcacc
    23761 gggcgtattc ttaatattaa cgttccggat ttacccttgg atcaaatcaa aggtattcgc
    23821 gtgacgcgct gcggtacacg acatccggca gatcaggtga tcccgcagca agatccgcgc
    23881 ggcaatacgc tgtactggat tggcccgccg ggcggtaaat gtgatgccgg tccggggacc
    23941 gattttgctg cggtagatga gggctatgtc tccatcacgc cgctgcatgt ggatttaact
    24001 gcgcatagcg cgcaagatgt ggtttcagac tggttaaaca gcgtgggagt tggcacgcaa
    24061 tggtaagcag acgcgtacaa gcacttctgg atcaattacg tgcgcaaggt attcaggatg
    24121 agcaggtgct gaatgcactt gccgccgtgc cgcgtgaaaa attcgttgat gaagcgtttg
    24181 aacaaaaagc ctgggacaat atcgccttgc cgataggtca ggggcagaca atttcgcagc
    24241 cgtatatggt ggcgcgaatg accgaattac tcgagctgac gccgcagtcg cgggtgctgg
    24301 aaattggcac tggttcggga tatcaaacgg caatcctggc gcatcttgtc cagcatgttt
    24361 gctcggtcga acggattaaa ggtttgcagt ggcaggcgcg tcgccgcctg aaaaatcttg
    24421 atttacataa tgtttcaacc cgtcatggcg atggatggca aggttggcag gcacgcgcgc
    24481 cgtttgacgc tatcattgtt acggcggcac cgccggaaat tccaactgcg ctaatgacgc
    24541 agctggacga aggcgggatt ctcgtcttac ccgtagggga ggagcaccag tatttgaaac
    24601 gggtgcgtcg tcggggaggc gaatttatta tcgataccgt ggaggccgtg cgctttgtcc
    24661 ctttagtgaa gggtgagctg gcttaaaacg tgaggaaata cctggatttt tcctggttat
    24721 tttgccgcag gtcagcgtat cgtgaacatc ttttccagtg ttcagtaggg tgccttgcac
    24781 ggtaattatg tcactggtta ttaaccaatt tttcctgggg gataaatgag cgcgggaagc
    24841 ccaaaattca ccgttcgccg cattgcggct ttgtcactgg tttcgctatg gctggcaggc
    24901 tgttctgaca cttcaaatcc accggcaccg gtcagctccg ttaatggcaa tgcgcctgca
    24961 aataccaatt ctggtatgtt gattacgccg ccgccgaaaa tggggacgac gtctacagcc
    25021 cagcaaccgc aaattcagcc ggtacagcag ccacaaattc aggctactca acaaccgcaa
    25081 atccagccag tgcagccagt agctcagcag ccggtacaga tggaaaacgg acgcatcgtc
    25141 tataaccgtc agtatgggaa cattccgaaa ggcagttata gcggcagtac ctataccgtg
    25201 aaaaaaggcg acacactttt ctatatcgcc tggattactg gcaacgattt ccgtgacctt
    25261 gctcagcgca acaatattca ggcaccatac gcgctgaacg ttggtcagac cttgcaggtg
    25321 ggtaatgctt ccggtacgcc aatcactggc ggaaatgcca ttacccaggc cgacgcagca
    25381 gagcaaggag ttgtgatcaa gcctgcacaa aattccaccg ttgctgttgc gtcgcaaccg
    25441 acaattacgt attctgaatc ttcgggtgaa cagagtgcta acaaaatgtt gccgaacaac
    25501 aagccagctg cgaccacggt cacagcgcct gtaacggtac caacagcaag cacaaccgag
    25561 ccaactgtca gcagtacatc aaccagtacg cctatctcca cctggcgctg gccgactgag
    25621 ggcaaagtga tcgaaacctt tggcgcttct gaggggggca acaaggggat tgatatcgca
    25681 ggcagcaaag gacaggcaat tatcgcgacc gcagatggcc gcgttgttta tgccggtaac
    25741 gcgctgcgcg gctacggtaa tctgattatc atcaaacata atgatgatta cctgagtgcc
    25801 tacgcccata acgacacaat gctggtccgg gaacaacaag aagtgaaggc ggggcaaaaa
    25861 atagcaacca tgggtagcac cggaaccagt tcaacacgct tgcattttga aattcgttac
    25921 aaggggaaat ccgtaaaccc gctgcgttat ttgccgcagc gataaatcgg cggaaccagg
    25981 cttttgcttg aatgttccgt caagggatca cgggtaggag ccaccttatg agtcagaata
    26041 cgctgaaagt tcatgattta aatgaagatg cggaatttga tgagaacgga gttgaggttt
    26101 ttgacgaaaa ggccttagta gaagaggaac ccagtgataa cgatttggcc gaagaggaac
    26161 tgttatcgca gggagccaca cagcgtgtgt tggacgcgac tcagctttac cttggtgaga
    26221 ttggttattc accactgtta acggccgaag aagaagttta ttttgcgcgt cgcgcactgc
    26281 gtggagatgt cgcctctcgc cgccggatga tcgagagtaa cttgcgtctg gtggtaaaaa
    26341 ttgcccgccg ttatggcaat cgtggtctgg cgttgctgga ccttatcgaa gagggcaacc
    26401 tggggctgat ccgcgcggta gagaagtttg acccggaacg tggtttccgc ttctcaacat
    26461 acgcaacctg gtggattcgc cagacgattg aacgggcgat tatgaaccaa acccgtacta
    26521 ttcgtttgcc gattcacatc gtaaaggagc tgaacgttta cctgcgaacc gcacgtgagt
    26581 tgtcccataa gctggaccat gaaccaagtg cggaagagat cgcagagcaa ctggataagc
    26641 cagttgatga cgtcagccgt atgcttcgtc ttaacgagcg cattacctcg gtagacaccc
    26701 cgctgggtgg tgattccgaa aaagcgttgc tggacatcct ggccgatgaa aaagagaacg
    26761 gtccggaaga taccacgcaa gatgacgata tgaagcagag catcgtcaaa tggctgttcg
    26821 agctgaacgc caaacagcgt gaagtgctgg cacgtcgatt cggtttgctg gggtacgaag
    26881 cggcaacact ggaagatgta ggtcgtgaaa ttggcctcac ccgtgaacgt gttcgccaga
    26941 ttcaggttga aggcctgcgc cgtttgcgcg aaatcctgca aacgcagggg ctgaatatcg
    27001 aagcgctgtt ccgcgagtaa gtgagcatct gtcagaaagg ccagtctcaa gcgaggctgg
    27061 ccttttttct ttcggttggt gagtcggtgt atttgtagtc tggataagac gcgatagcgt
    27121 cgcatccgga aatttgcccc ctatgcgttc atcatcttgc gcaccagctg cataaacagc
    27181 tcctgctctt ctccactcaa acgccccaaa aattcctcat ccacgctgtc accaatgggt
    27241 atcgccgcag caagtatctt ttcgccttcg gcagtcaacc agacaaagcg tcgccgctta
    27301 tcagcggggt catgttcacg tctgactaag ccacgatttt ccattcttgc caacatttct
    27361 gctaacgttg ctttggtgct gacagctgct tctatcagtg ccacctgttc gataccaggt
    27421 ttatcagcaa tggcgcgcat caccgcgtac tgtggtttgg tcaggtcagg taactcgtgc
    27481 tgccagcgag ccgtgtgctg ctgaaaaagc tgtcgtaact gatggaacgc tttatttcgt
    27541 aacgccatgt aaactccggg ctaattctct gtcgctatca tagcggtttt ttagtgacga
    27601 agaagatgtt gttacttttc aatccttgcc gctgtggaaa tgaaggagta tgttaataat
    27661 aacgttcgca tacgaacaat taagagaata agcaatgaaa ctgatcgtcg ggatgacagg
    27721 ggctaccggt gcgcctcttg gtgtggcatt actgcaagcg ctgcgggaga tgccgaatgt
    27781 cgagactcat ctggtgatgt cgaagtgggc gaaaaccacc attgaactgg aaacgcctta
    27841 cagcgctcgc gatgttgctg ccctcgcaga cttcagccat aacccggcgg atcaggcggc
    27901 gatcatctca tccggttctt ttcgtaccga cggcatgatc gttattccgt gcagtatgaa
    27961 aacgctcgcc ggtatccgcg ctggttacgc cgatggcctg gtagggcgcg cggcggacgt
    28021 cgtgctcaaa gaaggccgca aactggtgct ggtgccgcga gaaatgccgc ttagcaccat
    28081 ccatctcgaa aatatgctcg cactttcacg catgggcgtg gcgatggtgc cgccgatgcc
    28141 tgccttttat aaccatcccg aaacggtaga tgacattgtc caccatgtgg tagcccgcgt
    28201 gctggatcaa tttggcctcg aacatcccca cgccaggcgc tggcaaggat tgccgcaggc
    28261 ccggaatttt tctcaggaga atgaataatg gcatttgatg atttacgcag ctttttacag
    28321 gcgcttgatg accacggcca gttactgaaa atcagcgaag aggtgaacgc tgagccggat
    28381 ctggcagcag cagctaacgc caccgggcgt atcggcgacg gcgcgcccgc gctgtggttt
    28441 gataatattc gcggctttac cgatgcccgc gtggcgatga ataccatcgg ttcctggcag
    28501 aaccacgcga tttcccttgg cctgccacca aacaccccgg tcaaaagcag attgatgagt
    28561 ttatccgccg ctgggagaac ttcccgattg ccccggagcg ccgcgccaat ccagcctggg
    28621 cgcagaacac cgtcgatggc gaagagatca acctgttcga tattctgccg ctgtttcgtt
    28681 taaacgatgg cgatggcggt ttctatctcg acaaagcctg cgtggtttcc cgcgatccgc
    28741 tcgacccaga taacttcggc aagcagaacg tcggcatcta ccgcatggaa gtgaagggca
    28801 agcgtaagct cggcctgcaa ccggtgccga tgcacgatat cgccctgcat ctgcataaag
    28861 cagaagagcg cggtgaagat ctgccgattg cgatcacgct cggtaacgat ccgatcatca
    28921 cgctgatggg ggccacgccg ctgaaatacg atcagtctga gtatgaaatg gcaggcgcgc
    28981 tgcgtgaaag cccgtacccg atcgccaccg ccccgctgac cggttttgat gtgccgtggg
    29041 gttcagaagt gatcctcgaa ggggttatcg aaagccgtaa acgcgaaatc gaagggccgt
    29101 tcggtgagtt taccgggcac tactccggcg ggcgtaacat gaccgtggtg cgtatcgata
    29161 aagtctctta ccgcaccagg ccgattttcg aatcgctgta cctcggtatg ccgtggaccg
    29221 aaatcgacta cctgatgggg ccagccacct gcgtgccgct gtatcagcag ctgaaagccg
    29281 agttccctga agtgcaggcg gtaaacgcca tgtacaccca tggcctgctg gcgattatct
    29341 ccaccaaaaa acgctacggc ggctttgccc gcgcggtggg cctgcgcgca atgaccacgc
    29401 cgcatggtct gggctacgtg aagatggtga ttatggtcga tgaagacgtt gacccgttca
    29461 acctgccgca ggtgatgtgg gcgctctcct cgaaagtgaa cccggcaggg gatttggtgc
    29521 agttgccgaa tatgtccgtg ctggaactcg atccaggctc aagccctgcg gggatcaccg
    29581 acaagctgat tatcgacgcc actacgcctg tcgccccgga caaccgtggt cactacagcc
    29641 aaccggtggt ggatttaccg gaaaccaaag cctgggctga aaaactgacc gctatgctgg
    29701 ctgcacgtaa ataaggagaa gaagatgatt tgtccacgtt gtgccgatga acagattgaa
    29761 gtgatggcga aatcgccggt gaaagatgtc tggacggtat atcagtgcca gcattgcctt
    29821 tatacctggc gcgataccga accgctgcgc cgtaccagcc gcgaacatta tcccgaagcg
    29881 ttccgcatga cgcagaaaga tattgatgac gcgccaatgg tgccgagcat cccgccgctg
    29941 ctggtggaag gtaagcgtta aataaaaggt ccgatgccca tcggaccttt ttattaaggt
    30001 caaattaccg cccatacgca ccaggtaatt aagaatccgg taaaaccgag aatggtcgtt
    30061 aacactgtcc aggttttcag accgtctgct accgacaacc ccagatattt ggtcacaatc
    30121 cagaaccctg agtcattaat atgtgacgcg ccaagcccac caaagcaggc tgccagcgtc
    30181 accaatacgc actgaatcgg attcaatccc atcaccgctt ctgagagtaa cccgccggtt
    30241 gtcaggattg ctacggttgc tgacccctgc gatgcacgca gagccagtga aataataaat
    30301 gcggctggta acagaggcag gtcaatcatt tgtagcatat tggcaagggc tttgccgacg
    30361 cccgattcca ccagcacttt gccaaatacc cctccagcac cagtaaccaa aatcactacc
    30421 gccgcagtgg gaagggctga gcccataatg tcgctggtgt gttgtaagct ccagccgcga
    30481 cgtaaagcca ataaccagaa tgccagcacc agcgcaatca ttagagctac cattggtgag
    30541 ccgatcagct gtagcgtacc aagcagggga tgcgaaggcg gcatcagtgt tgcggaaacc
    30601 gtacccgcca tgataatcgc gataggaata acaattagcg aggtgaccag cgcgacgccc
    30661 ggtggattta ttttatcgct taattttgtc gcgccttcct cactggccgg agccagttgc
    30721 atctgttcca gtacttccac cgacatcgca tattggtgct tattgattat tttcgctgca
    30781 aagtagccaa caatccctac gggaatagaa atcgcaatac cgatgatggt tagccagccg
    30841 atgtctgcgt ggagtaaccc cgctgcggcg acagggcctg gatgcggcgg taccgccaca
    30901 tgtacagtta gcatgatccc agcgacaggc aggccaaatt tgagtggcga tattttggca
    30961 accttggcaa aaccgtaaat gattggcgca agaataataa agccgacatc aaagaagacg
    31021 ggaataccga ggaagaacgc tgccagagtc agcgcagcga tagttcgttt gtcacctaac
    31081 ttgcgactga aataattagc cagtgactct gcaccaccag agtgttcgat catacgcccc
    31141 agcatagcgc ccagaccaat aataatagtg acggaaccaa gcacaccgcc catcccggcg
    31201 atcatcactt tacccacttc gcccgccggt atacccgccg caagtgcgac taacaggctg
    31261 acgaggagca gagcaacgaa tggttgtacc tttgccttga tgaccagcag caacagcatg
    31321 attacgccag ctaacgcaat gcataacaat gtaattgtgg acatgggaaa ccctgtctga
    31381 aagttatagt taacctaccc catccgtaga tggggggatg tatgggtacg ttgtaattag
    31441 ggatttaacg aattagcgcc aggcgtcaaa ccagccaagc ccttcttcgg tgaggccacg
    31501 aggtttatat tcacaaccga tccagccctg atatcccacc tcatcgaaca ggcggaacag
    31561 ccacggatag ttgatttctc catcgtccgg ttcatgtcga tcaggtagtc cggcaatttg
    31621 tacgtgcgca tatttcccgg cgtagtcgcg gattaaatgc gtcaggttgc catctacttt
    31681 ttgcgcatga aaagtatcta gttgaataaa cacgttatct cgcgcaacct cttcaacaat
    31741 agccagtgcc tgatactggc tggagaagag ataatgaggc ttaacgccgg ggctgagtgc
    31801 ttcaactaat attcgcttgc cgtgtggcgc aaagcggtcg gcagcgtagc ggagattatc
    31861 gataaatact gcccggtacc gttcagcgtc ttcgccagcg ggcacgacgc ctgccatcac
    31921 atggacttgt tcacaattga gcgccaatgc atattccagt gccaggtcga tgtctgcgtg
    31981 tgcttcgtgc tcacgtccgg gaagggcgga taatccccat tcccccgcat taatatctcc
    32041 gggagcggta ttgaacagcg ccagtgtcag atggttttgc tccagttgct tttggatttg
    32101 cagggtggag tagtcatagg gaaacagaaa ttccacagca tcgaacccgg cttttcgcgc
    32161 tgcggcgaag cgttcaataa aaggcacttc ggtgaacatc atggataaat tagctgcaaa
    32221 acgaggcatt gcattaactc cttaattccg caatttcacc tgcggtcaga taacggatcg
    32281 ggcggtcacc gagaataaaa atcagctttg ccgtttcctc cagctcttcc atattgttgg
    32341 cggcttcttg caggctttca ccgcaaacca ctgggccatg atttgccagt aaaaaagcct
    32401 gattgtctgc tgccagttcc gccagatcct gtgcgatgcg tttatcgccc ggtcggtaat
    32461 aaggcaccag cgggacattt cccatccgca tcaccacgta tggtgtgaac ggacgaataa
    32521 cgttgctgct gtccagccct tgcaggcagg aaagcgccgt cgaccatgtg ctgtgcaaat
    32581 gcaccaccgc tttacagcgc ggattgttgc gatacagcgc cagatgaaag agcacctctt
    32641 tcgagggttt gtcaccactt aaccattcgc catccgcggc gactttggaa agccgctgcg
    32701 gatcgagatt gcccaggcat gaacctgtcg gtgtcgccag taaattcccg tcaggtaaaa
    32761 gcagcgacag attgccagcc gaaccggttg catagccgcg ctgaaagaat gaactggcaa
    32821 tccgcgtcat ctcctctcgc aaagactgct ctacttttgc gaaatcgctc atgataaaaa
    32881 ctctctttgg gctcgtgaaa aaaaggcttc atcaccgaag ttgccagatt taagggcgag
    32941 tgagacaggc ttatccagtg cgtttaccca cggcacgccg ggggaaatgg ttgggccaat
    33001 atgaaaccct tttatgccca ggctctgtgt gactacgccg gaggtctcac cgcctgcgac
    33061 aataaagcgt gtcacgcctt ccgctgctaa ccgcgccgct agttgagaaa atagagtttc
    33121 tactgcctga ctggcttttt gtgcaccgta ttgctgttga attgctgcca atgcgtcagt
    33181 gctggcggtg gcaaaaacca gtggagcaag tacactttcc tggcccagaa cccactctgc
    33241 cagttcgtgt gcataagcgg ccagagtttc ggttgagagg cagcgtgcca catcaacttc
    33301 acgggctggt gcaatttgac ggtaatgtgc cacctggcgg ttggtcattt gagagcatga
    33361 accggagagc actacgccgc gcccagcgag cggatgccct gcttcgcgag cctggttacc
    33421 gttttcttgc gcccactgcc gggccaggcc aatcgccaga ccagaaccgc ccgttaccag
    33481 tggggcatcg cgcaaggctt ctccctgaat ttccagatgg tgttcggtca gcgcatcaag
    33541 caccgcgtag cggtagccct cttgctgtaa gcgagccagc tcttgacgaa cggcatccac
    33601 accttgttcg aaaacatgtg ccgaaacgac gccgcagcgc cctgtggatt gcgcttcaac
    33661 cagacgggga agatagctgt cggtcatggg atttaccggg tgatggcgca tcccggattc
    33721 ggccagcagt tgattcatta cgaacaaata cccctgataa accgtacgtc cgttgaccgg
    33781 cagggccgga gagaagaccg taaacggcgt gtcgagagca tccattaatg catcggtaac
    33841 cgggccgata ttacctttcg ccgtactgtc gaaagtagag cagtatttga aatagatctg
    33901 tttgcaacct tgctgttgca accagctcag agccgccagc gattgctgtg tggcttcaac
    33961 caccggacag gagcgcgttt tcaggctgat caccagtgcg tcgattgctt ccggcatttt
    34021 acctgttgga acaccgttaa tttgtaccgt tggtagaccg ttttccacca gaaaactggc
    34081 gatatccgtc gcgccggtaa aatcatcggc gataacgcca atcttgatca tgatttcgct
    34141 cccggtagag tgatgccaga gaaaatcttg ataactgcgc tatcgtcttc tttcccgtaa
    34201 cctgcgttac tggcgctggt gaacatattc aatgctgttg aggccaatgg cagcgggaag
    34261 tgcagggctt tggctgtatc ggcaaccaga ccaagatcct taacaaaaat atcgacggct
    34321 gaatgcgggg tgtaatcgcc atccaccaca tgacgcatcc ggttttcgaa catccaggaa
    34381 tttccggcgg cattggtcac gacgtcatac atcacatcca gcgggatccc cgcacgggct
    34441 gcaagtgcca tcgcttcggc tccggcagca atatgtacgc ccgctaacaa ctggtgaata
    34501 atttttacgg tcgaacctag tcccggttct gcacctatgc gataaacttt tccggcaacg
    34561 gcttccagca cgggtgccag tcgttcaaag gcaatatcgc taccggaggc catgacagtc
    34621 atttcaccgt tagcggcttt tactgcacca ccagaaactg gcgcatccag catttccaga
    34681 tcgaatccag ccagagcggt agcaatttct tgcgcatcag cactagcgat agtggaagaa
    34741 accattactg ccgtaccggg tttcagatgt tgtgcaacgc ctgtttcacc aaacagcacc
    34801 tgtttaacct gggccgcatt gaccaccagc accagcagag cgtccagttt ttcggcaaac
    34861 gtcgcggcgt tatcagaaac cccgcaagca cctgcctctt tcaacgtagc gcaggcattg
    34921 ctgttcaggt ctgcgcccca ggtagaaaga cctgcgcgga cacatgacag tgctgctccc
    34981 attcccattg accctaagcc aacgataccg acatgaaact cagatcccgt tttcatctgc
    35041 tctccttgtt aatttaagtg atattttgtt tgatattgtg aatataagcg ctggaagata
    35101 acgatatggt gagctgattc acataaatta acattgtgtg ttattttatg tgaactaagc
    35161 gttagttgcg ccgcgcacgt ttcgcaggca aatagcgtag aatgtcagca ggacaaagga
    35221 aggagcaaaa gttgataccc gtagagcgtc gccaaatcat ccttgagatg gtagctgaaa
    35281 aaggcattgt cagtattgct gaactaacgg acagaatgaa tgtgtcacat atgaccattc
    35341 gtcgggattt acaaaaactg gagcagcagg gagccgttgt gctggtgtcc ggaggcgtcc
    35401 agtctccggg acgcgtggcg catgaacctt ctcatcaggt aaaaactgcg ctggcaatga
    35461 cgcaaaaagc ggctattggc aagctggcgg caagtcttgt tcagccggga agttgtatct
    35521 atctggatgc gggaacgacc acgttagcga tagcacagca tctgattcac atggagtcac
    35581 tgactgtggt cacaaacgat ttcgttattg cgaactactt gctcgacaac agtaattgca
    35641 caattattca cactggcggt gcagtgtgtc gggaaaaccg ttcctgtgtc ggggaagccg
    35701 ctgcgaccat gctgcgcagc ctgatgattg atcaggcttt tatttctgca tcgtcatgga
    35761 gtgtgcgggg gatttctacg ccagcggaag ataaagtcac ggtgaaacgg gcgattgcca
    35821 gtgccagccg ccagcgagtt ttggtctgtg atgcgacgaa atatggtcag gtggcgacat
    35881 ggctggcgtt accattaagc gagtttgatc agattattac agacgacggt ttgccggaga
    35941 gtgccagtcg cgcgctggcg aagcaggatc tctctttgct ggtagcgaaa aatgaataat
    36001 ggcctgcaat aacaccgggt tactcatgct tcacagaaga agcatgagac tactttattt
    36061 tataaaatga cagccgcccg cttttcggcg atccggtatc aatataaatc tggttagcga
    36121 acgtctgaat gttatcaaac atcatatgtc caaatataaa ataatcagcg ccgtttattt
    36181 gttgtaactc gccattaagc gatttctgca cacgatcaac aggccagagt aattcgctct
    36241 ccgctatttc tttaccaaag agatattcac tccccggata atctgcatgt gcgatgacat
    36301 attttatgtt gtcgttagtg atttcaataa tatgtggaag gtgatggaat ttcagcaaca
    36361 gatctgtagc ttctttttgc tctgaatcat ttaaatcgaa aaaccagtca ccaccgctgg
    36421 caagccacac attgccatcg ccggtcgcga acgcatccag cgccattgct tcgtggttgc
    36481 ctttaacgga gataaaccag ggctggttta gcaggcgcag gacgtcaaga ctctccggcc
    36541 cacgatcaat attatcgccg acagaaataa gtaagtcggt ttcagggcaa aaagagagtt
    36601 gatgtaagcg ggattgtaat aattgatatt caccatgaat atcaccaacg acccatatat
    36661 ggcgatagtg atgggcatta attttttgat agcgtgtaga tggcatggtt ttaccctgta
    36721 aaataagctt tcctattata cagggtgttt ttattttatt cgtcagttgt cgttaatatt
    36781 cccgatagca aaagactatc gggaattgtt attacaccag gctcttcaag cgataaatcc
    36841 attccagcgc ctgacgcgga gtcagtgaat ccgggtccag gttttccaga gcttcgaccg
    36901 ctggcgaggt ttcttccggt actgacagca aagacatttg cgtaccatcc acttgcgtag
    36961 cggtggcgtt cggcgaaatg ctttccagct cacgcagttt ttgccgtgcg cgcttaatca
    37021 cctcttttgg cacgcctgcc agagctgcaa ccgccaggcc gtagcttttg ctcgccgcgc
    37081 catcctgcac gctatgcata aaggcaatgg tgtctccgtg ctccagcgca tcgagatgca
    37141 cgttggcgac gccttccatt ttctccggta actgtgtcag ctcgaaatag tgggtggcaa
    37201 acagcgtcaa tgccttaatc ttattcgcca gattttccgc gcacgcccac gccagcgaca
    37261 gaccatcgta agtggacgtt ccacgcccga tctcatccat caataccaga ctatattcgg
    37321 tggcattatg taaaatattg gcggtttcgg tcatctccac cataaaggtc gaacgcccgg
    37381 aagccaggtc atctgccgcg cctacgcggg taaagatacg gtcaatcggg ccaatctcga
    37441 ctttttgcgc cggtacgtag ctgccgatat aggccattag cgcaatcaac gcggtctggc
    37501 gcatataggt acttttaccg cccatgttcg gaccggtgat gatcaacatg cgacgctgcg
    37561 gcgacagatt cagcgggttg gcgataaacg gctcattcag cacctgttca accaccggat
    37621 ggcggccttc ggtaatgcga atgcccggtt tatcaataaa ggtcgggcag gtgtagttca
    37681 gggtataggc ccgttccgcc aggttcacca gcacgtcgag ttccgccagc gcgctcgcgc
    37741 tctgttgcaa cgcttccaga tgcggcaaca gcaggtcgaa cagttcttca taaagctgtt
    37801 tttccagtgc cagtgctttg ccttttgagg tgagaacttt atcttcgtac tcttttagct
    37861 ctggaatgat gtagcgctcg gcgtttttca gcgtctggcg acgcatgtag ttgatgggtg
    37921 ccagatggct ttgcccacgg ctgatttgaa tgtagtagcc gtgcaccgca ttaaagccaa
    37981 ctttcagcgt gtccaggccg gtacgttcac gctcgcggac ttccagacgc tccagataat
    38041 cggtcgcgcc gtcagccagc gcgcgccact catccagctc ttcgttatag cccgatgcga
    38101 taacaccacc gtcgcgtacc agcaccggcg gtgtgtcgat gattgctcgc tccagcagat
    38161 cgcgcagctc ggcaaactcg cccatcttct cacgtagcgc ctgtaccggt gcactatcga
    38221 cagtttctaa ctgcgcacgc agctccggca gttgctggaa agcgtggcgc atacgggcca
    38281 gatcgcgtgg gcgagcagtt cgtaaagcca gacgtgccag aatacgttcc aggtcgccga
    38341 cctgacgcag taccggctgc aactcggcgg tgaaatcctg caatgcgcca atagtttgct
    38401 ggcgctcaag caacacgcgg gtatcgcgca ctggcatatg cagccagcgt ttcagcatac
    38461 gactacccat cggcgtgacg gtgcagtcga gcacagaagc cagcgtattt tccgcaccgc
    38521 ccgccaggtt ctgagtaatt tccaggttac gacgtgtcgc ggcatccata atgatgctgt
    38581 cctgctcacg ttccatggtg atagaacgaa tatgcggcag ggtcgtgcgt tgggtatctt
    38641 tcgcatactg caacagacaa ccggcagcac aaagtccgcg cggcgcgttc tcgacgccaa
    38701 aaccgaccag atcgcgggtg ccaaattgca gattcaactg ctggcgcgcg gtgtcgattt
    38761 caaactccca cagcgggcga cggcgcaggc cgcgacggcc ttcaatcagc gacatctcgg
    38821 cgaaatcttc tgcatacagc agttccgccg gattagtgcg ttgcagctct gccgccatcg
    38881 tttcgcggtc ggccggttcg ctcaggcgaa aacgcccgga gctgatatcc agcgtcgcgt
    38941 agccgaaacc tttgctgtcc tgccagatag ccgctagcag gttgtcctga cgctcctgca
    39001 acagggcttc atcgctgatg gtgcctggcg taacgatacg cacaactttg cgctcaaccg
    39061 gacctttgct ggtcgccgga tcgccaattt gttcgcagat ggcaacggac tcgccctgat
    39121 tcaccagttt ggcgaggtag ttttccaccg catggtaggg gatccctgcc atcgggatcg
    39181 gctctcccgc cgaagcaccg cgtttggtca gtgaaatatc cagcagttgc gacgcgcgtt
    39241 ttgcgtcgtc ataaaacagt tcataaaaat cacccatccg gtaaaacagc aggatctcgg
    39301 gatgctgggc tttcagcttg agatactgct gcatcatggg cgtatgggcg tcgaaatttt
    39361 ctattgcact catggggtta tgtccggttc cctgatatta aatggggtgt gatggttttt
    39421 attttcgttg taatcacata aggcgcacat gataccggag ttaatcattt caggggaaga
    39481 agcgaacggc gagttcttga tgctggttcc gggaaagatg ctgttttgca gcttttgcgt
    39541 gatgcttatg aagcaagtac gcaaaattgc gtcggttgaa taaacctcct ccttcagagc
    39601 catagtcccc tttcaaatta agttgtaata taaatacacc ttaagagtat ggaggcagca
    39661 tgtccggcaa gcgtatctct cgtgaaaaac tgacgattaa aaaaatgatc gatctttatc
    39721 aagcgaaatg cccgcaggcg tcagcggagc cggagcatta cgaggcgttg tttgtttacg
    39781 cgcaaaagcg gctggataaa tgtgtgttcg gcgaagagaa accagcctgt aagcagtgtc
    39841 cggtgcactg ttaccagcct gcaaagcgtg aagagatgaa acagattatg cgttgggccg
    39901 ggccgagaat gctgtggcgt catccgatct taaccgtgcg tcatctcatc gatgacaagc
    39961 gtccggtgcc agaactgccg gaaaaatatc gtccgaaaaa acctcgtgaa tagtatgccg
    40021 gacaggcaga tctgtccggc aatttgcagt taaatcaatg ccgatttatc aattcccagc
    40081 cgcttcatcc gtgacagcag ggtcgtgcgt ttcagcccca gacgttgcgc agcgccttta
    40141 ggcccggcaa ccacgccgtt ggtttctttc agcacgcgaa caatcaactg atattcatct
    40201 tcgccctcct gggcgacaac cgttgcggca ggcggcgttt caggttccgg taaaacaata
    40261 tctggcaatg acagctgcag cacgttaccg cgtgttagca ataccgcgcg ctcaatgacg
    40321 ttttccagtt cgcgtacgtt acccggccac tccatgttgc tcaaggtgcg cagcgtctcg
    40381 gcaggaatgc tgtcgatatt gcgccccaga cgacgggcaa ttttgaaggt aaaggctttc
    40441 gccagcagcg gaatatcttc cggacgctcg cgtagtggcg gcaggtgaat cgggaatacg
    40501 ttcaggcggt aatagagatc gctacggaac tcacggtcgg cgaccatttt tttcagatcg
    40561 cggttagtcg cggcgattag acgcacgtcc gtctgaatga ttttgttgct gccgagacgt
    40621 tcaaactcct gttcctgcaa tacacgcagc aacttcggct gtaactccag tggcatatcg
    40681 cccacttcgt cgaggaacag ggagctttta tccgccagtt caaaacgacc aatgcgctgg
    40741 gcgctggcac cggtaaaagc cccacgctca tgaccaaaca gatcgctttc cagcaatccg
    40801 gcaggcatcg ccgcgcagtt cattttgacc atgcggcgat tattacgccc actgagatta
    40861 tggatcgcac gggcaatcag ctctttaccc gtgccagttt caccgaggat cagcacggta
    40921 ctgtcacttt gcgccaccat ttcaacttgt ttaagcacgc tgtacatggc ttcgctgcgg
    40981 ccaataatct cgccaaattc actatcaaca ttgttgagct gctcggtcag ggcgaggttt
    41041 tcatcaacca gccgttcttt cagacgatgg atttcctgat aggcgagggc gttatcgaca
    41101 gcgattgcca cacgttcggc aatctggcgc agtaaattca gattggtagt ggtaaacact
    41161 ttctcttcgc attgcgccag tttcagcacg cccagcatgg tgtcgccaga catcagcggt
    41221 aacaggcaca aggtttgaat ctggttgccc caggtgtcga acaacatgcg ttcatagggg
    41281 gctaaatcgt cccgctcgtg gagattgatc agcagcatct ctttactttt gaacacgcgt
    41341 tcggtgaggg ttccggcttc atcgacttcg ctctgttcgt gggcgggatg ttgtttatca
    41401 agatagtgag tggagtagat gttgagtttg tttttacggt ggctgcgtaa gacgatactg
    41461 atatcgtcaa tgtcgaaata gtaatggatt tctttggcga cttcgctgac cagttcgtcc
    41521 atatccaggc gggaaagcac cgcgttggta atggcaacca ggatgcggaa gttatcgcgc
    41581 tcccggcata acaactcata gtcgacattg ttgacgacgc ggctctggat ttgttcggtg
    41641 acgacagaaa cgatctgcgt aaatgtttgc agacgattga actctttttc gctccagggg
    41701 cgatcgtcat aacgaataaa ttcacagcca ccaaaaatat gcccttctgc cgccagtggc
    41761 atcaggcaat agtgaccaaa ttttgggtat agcccacctg cggccagctg cggccaggtt
    41821 tcacaaaatt cttcgtaact gcaatgcagc gtatcagggc gcgacaaaat gctgcgtacc
    41881 ggaccgtgtg ccagaacagt ttcgtcttca tatttaatgg gggtgtcttt ttcacgcgat
    41941 gcgtaataag acgcacgttg agtctgcgct tgccacaaca caatagccgc gttgtcggcg
    42001 agcgcagaac gctttaccag ttgcgaaaga gcctcacaca gcgaggccag atcgggctgc
    42061 tgcaatagtg tccgagtgat gtcgaacaac ccttgctgtc cgagatcact catcggtgta
    42121 tatgacattt tgttcttcca ggaaagcacc gcaaagcggt gcaaaaggtc attgactaac
    42181 tataggagat ttagaatttt attagcatat acgcggaagc ggttcggcgt gtggtaaatc
    42241 gagggttcgt ttcacgccat acagaccggc aagacgaaca cctttacgtt ccaccacttc
    42301 accaatcagc gccgcgtctt tccccagtgg atgggaatgt aacgctgcca gcacttgctc
    42361 tgccgcgttg cgttcaacgg cgatcaccag tttgccttcg ttggcaaagt taagggcgtc
    42421 cagtcccagt agttcacaaa cgccgcgcac agcaggttta accggcagtg ccgcttctga
    42481 aatttcaata ccacaaccgc aggctgccgc gaactcatga actaccgcgt tcacaccacc
    42541 acgggtggca tcacgcagcg ctttcacgcc gggaatgtca cgcagcgtct gaataagcgg
    42601 cgtcagtacc gcgcagtcgc tgaccagttc gccatccagc cccagctgct cacgcaggtt
    42661 aaggatagtc gccccgtggt ccccgagcgt gccgctaacc agtaatacat cgcctgcggt
    42721 tagcgtctgt gcgccccagt gaatattcgc cggaattgcg cccatgccag cggtgttgat
    42781 aaacagttta tctgccgcgc cgcgctgcac cactttagta tcgccagtga cgatggcaat
    42841 gcctgccgcg cgcgcggttt ctgccatgct ggtcactacg gctttcagtg tctccatcgg
    42901 caatccttct tcgaggataa agccacagga gagatagcgc ggaatagcgc cactgaccgc
    42961 aacgtcattg gctgtgccgc aaatcgccag cttgccgata ttaccgccag gaaagaacag
    43021 cgggtcaatg acgtaactgt cggtggagaa cgccagacgg tcgccttccg ctaccagctg
    43081 cgccagctca agacgtgcct gatcttcctg ttctgccagc cacgggttgg caaaggcttc
    43141 cataaacagg ctgttgatta attgctgcat cgcctggccg ccgctgccgt gggcgagttg
    43201 gatattattc acgcttcact ctcctgctga cgatactgat accacgcggc gcacgctcct
    43261 tcggaggaga ccatcagtgc accaaatgcg gtttgaggat tacaggtgtt accaaacagc
    43321 gggcattgat gcggcttaca tttgcccgtt aatacttcac cacaacgtgc gcgcgggtca
    43381 tcgcagacct gctgcggtgc cgggcggaaa tgcgcttcgg catcgaatcg ttgataatct
    43441 ggcgtcaggt gtacaccaga agattcaatc acgcctaagc cgcgccattc gctgtcgccg
    43501 ttgacacaga acacatcggc aatcgcctgt tgcgccagca ggttaccggc atccggtacc
    43561 acccgacgat actgattctc taccttgctg tgggccgcta ttttctgctc caccagcatg
    43621 accacgcctt gcagtagatc aagcggttcg aaaccagcca ccaccagcgg acgatgaaaa
    43681 tcgctggcga taaaattata ggcatcagtg ccgataacca tactaacgtg gcccggcgcg
    43741 aggaacgcgt cgataccgtt atccggctgt tccagcaaac tgcgaagcgt cgggataagc
    43801 gtaatatgct ggcagaagaa gtaaaaattc tgcacatcac gcgctttcgc ctgttgcaga
    43861 gtgatggcgg tggtcggcat ggtggtttca aaacctaagc cgaagaacac cactttgcgg
    43921 gttggattct cctgcgccag tttcaacgca tccatcggcg agtaaacgat gcgcacatcg
    43981 gcaccgcgtg cttttgcctg caacagcgaa ccctgtttcc ctggtacgcg catggcgtcg
    44041 ccaaaggtac agaagatgac ttccggatgg ctggcaatct ccacgcaggt gtcgattcta
    44101 cccatcggca gtacgcacac cgggcacccc ggaccgtgga taaactcaac gttttccggc
    44161 agtaactggt cgaggccgaa tttaaagata gcgtgggtat gaccgccaca cacttccata
    44221 atccgcagag ggcgttcggc ggtgtaagag agatgtgaag cacgttcgcg cagatgctca
    44281 attaactgca tcacctgttc cggcgcgcga tattcatcaa caaaacgcat tatttttcct
    44341 cgccatacaa cagcgcgccg acatccggct caacgtcaaa catgttttgt aaggcgtcga
    44401 gagtgtcgcg tgcttcggct tcattaatta cgctcatggc aaagccaacg tgtaccagta
    44461 cccactggcc cacgcgcggc tgaccgtttt catcgcagct gccgactaac gttaaatcga
    44521 catcgcgctg aatgccgcag acgtcgactt tcgcctggtt gccgtcaatg gtgcggatct
    44581 ggccgggaac gcctatgcac atcgctgtgt ctccagccag ttcagccact ggtctatccc
    44641 ttcgccgctg gtggcggaaa taaggatgat ttcaatttct ggattgactt cgcgggcgca
    44701 ggcgatgcac ttttcaacgt caaagttgag atacggcaac aggtcaactt tgttgagcag
    44761 catcagcgag gcggcggcaa acatatgcgg atatttcagc ggtttgtctt caccttcggt
    44821 aacggaaagc accgccactt tgtgtttttc accgagatcg aagctggccg ggcatacgag
    44881 gttgccaacg ttttcgataa acagaatacc gttatcgtcc agtggcagac gcggtgcggc
    44941 gtcggcaatc atctgtgcgt caagatggca gcctttaccg gtgttcacct gaatcgctgg
    45001 tgtaccggta gcgcgaatgc gtgcggcatc gttcacggtt tgctggtcgc cttcaataac
    45061 cgcgcacgga acgctgtctt tcaggcgcat tagggtttcc gtcagcaggg tggttttacc
    45121 ggaaccaggg ctggaaacca ggttgagcac cagttgcttg cgggcagcaa agcgcgcgcg
    45181 gttgcgttca gccagacggt tatttttgtc cagcacgtca atttcgactt ccagcatccg
    45241 acgctggctc atgcccggtg cgtgagtgcc cgcttcgcca tgaccgtaat gcaggtcgcc
    45301 ttcttcagtc tggctggggg taaattcagg cgctttaatg ccggtgattt tcatcttcgg
    45361 gcgtgccgcc ggggcaaatg gcgcgctacg aaacgcggaa tgagggttat gttcatcacc
    45421 ctcgatatac aggttgcctt caccgcaacc gcatgttgta cacatcgctc actcctggtc
    45481 tatttctatc cgccgaatct gtaaaccgtc gtctgccaca atctgtagca tgtcaccatg
    45541 acactgtgga cagcggcgga cgcgctgggt cagtagcgtc acatactgtt ggcatgtttc
    45601 acaccagcat tcggcctctt gttcttcgag gtgcagttta caaccttccg ccacgctgcc
    45661 gcggcaaacc agatcaaaac aaaaggcaag agagctggtt tcgacacaag aaaatgcgcc
    45721 aattttgagc cagaccccag ttacgcgttt tgcgccgtgt tttgcggcct gctgttcgat
    45781 caattccagt gcccgttggc agagggttat ttcgtgcata tcgcctccca ttaactattg
    45841 ccagctacaa gcaataattg tgccagtgtt gattatccct gcggtgaata atgtcgatga
    45901 tgtcgaaatg acacgtcgac acggcgacga aattcatctt tagcttaaaa atctctttaa
    45961 taacaataaa ttaaaagttg gcacaaaaaa tgcttaaagc tggcatctct gttaaacggg
    46021 taacctgaca atgactattt gggaaataag cgagaaagcc gattacatcg cacagcggca
    46081 tcgtcgccta caggaccagt ggcacatcta ctgcaattcg ctggttcagg ggatcacgtt
    46141 atcgaaagcg cgcctgcatc acgccatgag ctgcgcgccg gacaaagaac tctgtttcgt
    46201 cctttttgaa cattttcgta tttacgtcac cctggcggat ggctttaaca gccacaccat
    46261 cgagtattac gtcgaaacaa aagatggcga agacaaacag cggattgcgc aggcgcaact
    46321 gagcattgac ggcatgattg atggcaaggt caacatccgc gatcgcgaac aggttctgga
    46381 acactatctc gaaaaaatcg ctggcgttta cgacagctta tacaccgcca ttgaaaacaa
    46441 tgtgccggtg aatttaagcc aactggtaaa gggacaaagc ccggcagcat gagctgaggc
    46501 tttgcccgtt ttgcaggcgt tacgcctgtt tggggatggg cgtgtcgatg agtgtcgaaa
    46561 atgtcatttc atcggcatgt tttcgtcaaa aatgacaatc acctgaggaa tgcctggtga
    46621 atcgttttgt aattgctgac tccacgctct gtatcggctg ccacacttgt gaggccgcct
    46681 gttcagagac gcatcgccag cacggcctgc aatcaatgcc gcgcctgaga gtgatgctaa
    46741 atgaaaaaga atctgcgccg cagctctgtc accactgtga agatgcaccc tgcgcggtgg
    46801 tctgcccggt taacgccatc acccgcgttg atggggccgt gcagttgaat gaaagcctgt
    46861 gcgtaagctg caaactgtgc ggcatcgcct gcccgtttgg cgcaattgaa ttttccggca
    46921 gccgtccgct ggatattccg gcaaacgcca ataccccgaa agcgccaccg gcaccgcctg
    46981 ctccggcgcg tatcagtacg ctgcttgact gggtgccggg tattcgcgcg atcgccgtca
    47041 aatgtgacct ttgcagtttt gatgaacaag gtccggcctg cgtgcggatg tgcccgacca
    47101 aagccctgca tctggtggat aacaccgata tcgcccgcgt cagcaaacgt aagcgtgagc
    47161 tgacttttaa tacggacttt ggcgatctca ccttgtttca gcaggctcaa agtggagagg
    47221 ctaaatgagc gcaatttccc tgatcaatag cggcgtggcg tggtttattg ccgccgctgt
    47281 tctggcattt ctcttttctt ttcaaaagac gctaagtggc tggatagccg gaattggcgg
    47341 cgcggttggt agcctgtata cggcagccgc gggcttcact gtgctgactg gcgcggttgg
    47401 cgtgagcggt gcgctgtcgc tggtaagcta cgatgtgcaa atctccccgc ttaacgcgat
    47461 ttggctgatt accctcggcc tttgcggtct gtttgtcagc ctctataaca ttgactggca
    47521 tcgccacgcg caggtgaagt gcaacggctt gcagatcaat atgttgatgg ctgccgccgt
    47581 ctgcgccgtc attgccagca acctcggcat gttcgtggta atggccgaag tcatggcctt
    47641 gtgtgcggtg ttcctcacca gcaacagcaa agagggcaaa ctgtggtttg cgctggggcg
    47701 tcttggcact ctgctgctgg cgattgcttg ctggctgctg tggcagcgtt atggcacgct
    47761 ggatctgcgc ctgctggata tgcgtatgca acagctgccg ctcggttccg atatctggct
    47821 gctcggtgtg attggctttg gcctgctggc cgggattatt ccgctgcacg gctgggtgcc
    47881 gcaggcacat gctaacgcct ctgcgccagc tgccgcgttg ttttctacgg tagtcatgaa
    47941 aattggcctg ctgggcattt taaccctgtc gctgctgggt ggtaacgcgc cgctgtggtg
    48001 ggggatcgcg ctgctggtgc tcggcatgat caccgcgttc gtcggtggtc tgtatgcgtt
    48061 gatggaacac aacatccagc gcctgctggc ttaccacacc ctggaaaata tcggcattat
    48121 cctgctgggg ctgggcgctg gcgtaacggg tatcgcgctc gaacaaccgg cgctgattgc
    48181 tcttggtctg gtcggtggtc tgtaccatct gcttaaccat agcctgttca aaagcgtact
    48241 gttcctcggg gcggggagcg tctggttccg taccggtcat cgcgatatcg aaaaactcgg
    48301 tggtattggc aagaaaatgc cggttatctc catcgccatg ttagtcgggt tgatggcaat
    48361 ggctgcgctg ccgccgctga acgggtttgc cggggaatgg gttatctatc aatccttttt
    48421 caaactgagc aatagtggcg cgtttgttgc ccgtctgctg gggccgctgc tcgctgtggg
    48481 tctggcaatt accggtgcgc tggcggtgat gtgtatggcg aaagtctatg gcgtcacgtt
    48541 cctcggcgcg ccgcgtacca aagaagccga aaacgccacc tgtgcgccgc tcctgatgag
    48601 cgtaagcgta gtggcactgg cgatttgctg cgtaattggc ggtgttgctg cgccgtggct
    48661 gctgccgatg ctctctgctg ctgtacctct gccgctggag cctgctaaca ccaccgtttc
    48721 tcaaccgatg atcacattgc tgctgattgc ctgcccgctg ctgccattca tcattatggc
    48781 gatttgcaaa ggcgatcgtt tgccgtcgcg ttcccgcggt gcggcctggg tgtgcggcta
    48841 cgaccacgaa aaatcaatgg tgattaccgc tcacggtttt gccatgccgg tgaaacaggc
    48901 gtttgcgccg gtgctgaaac tacgcaaatg gctgaatccg gtgtctctgg tgccgggctg
    48961 gcagtgcgag gggagtgcgt tgctgttccg ccggatggcg ctggttgaac tggcggtgct
    49021 ggtggtgatt attgtttcac gaggagcctg agaatgagtg ttttatatcc gttaattcag
    49081 gcgctggtgc tatttgccgt tgcgccgctg ctctccggta ttacccgcgt ggcgcgagcc
    49141 cgcttacata accgtcgtgg gccgggtgtg ttgcaggagt atcgtgacat tatcaaactg
    49201 ctgggccgcc agagcgttgg cccggatgcc tccggctggg tgttccgcct gacgccgtat
    49261 gtgatggtgg gcgtaatgct gactatcgct actgcgctgc cggtggtgac cgttggttct
    49321 ccgctgccgc aactgggcga tttgatcacc ttactgtatc tctttgccat cgcgcgtttc
    49381 ttctttgcca tttccggtct ggataccggt agcccgttta ctgctatcgg cgcgagccgt
    49441 gaagcgatgc ttggcgtgct ggtcgaaccg atgctgctgc ttggtctgtg ggttgccgca
    49501 caggttgccg gttccaccaa catcagcaac atcaccgaca ccgtttatca ctggccgctg
    49561 agccagagca tcccgctggt gctggcgctc tgtgcctgtg cattcgccac ctttatcgaa
    49621 atgggcaaac tgccgttcga cctggcggaa gccgagcagg agttgcagga aggtccgctc
    49681 tctgagtaca gcggcagcgg ctttggcgtc atgaaatggg gtatcagcct gaaacagttg
    49741 gtggtgctgc agatgttcgt cggggtgttt attccgtggg gacaaatgga aaccttcacc
    49801 gctggtggac tgctgctggc gctggtgatt gccatcgtca aactggtggt cggcgtcctg
    49861 gttatcgcgc tgttcgaaaa cagcatggcc cgtctgcgtc ttgatattac tccgcgcatt
    49921 acctgggctg ggtttggctt tgcattttta gcgttcgtct ccttgctggc ggcgtgatta
    49981 aagagagttt gagcatgtct gaagaaaaat taggtcaaca ttatctcgcc gcgctgaatg
    50041 aggcatttcc gggcgtcgtg ctggaccacg cctggcagac caaagatcag ctgactgtca
    50101 ccgtaaaggt gaactatctg ccggaagtgg tggagtttct ctactacaag caggggggct
    50161 ggctgtcggt gctttttggt aacgacgaac gcaaactgaa tggtcattac gccgtttatt
    50221 acgtgctgtc gatggagaag ggcaccaagt gttgggtaac ggttcgtgtc gaagttgacg
    50281 ccaacaaacc ggagtatcct tccgtgacgc cgcgcgttcc ggctgcggtg tggggcgagc
    50341 gtgaagtgcg cgatatgtac ggtttgattc cggttggtct gccggatgaa cgtcgtctgg
    50401 tgctgccgga tgactggccg gatgaacttt atccgctgcg caaagacagc atggattatc
    50461 gtcagcgtcc ggcaccgacc accgatgctg aaacctacga gttcatcaac gaactgggcg
    50521 acaagaaaaa caacgtcgtg ccgattggtc cgctgcacgt cacttctgac gaaccggggc
    50581 acttccgtct gttcgtcgat ggcgaaaaca ttatcgacgc cgactaccgc ctgttctacg
    50641 tccatcgcgg catggaaaaa ctggcggaaa cccgtatggg ttacaacgaa gtgaccttcc
    50701 tctctgaccg tgtgtgcggg atctgcggct ttgctcacag caccgcctac accacgtcgg
    50761 tggaaaacgc gatgggtatt caggtgccag aacgtgcgca gatgatccgc gccattctgc
    50821 tggaggtgga acgcctgcac tcgcatctgc tcaacctcgg cctggcctgt cactttaccg
    50881 gcttcgactc cggctttatg cagttcttcc gcgtgcgtga aacctccatg aaaatggcag
    50941 agatccttac cggtgcgcgt aaaacctacg gcctgaacct gatcggcggg attcgtcgcg
    51001 atctgctgaa agatgacatg atccagaccc gccagctggc gcaacagatg cgtcgtgaag
    51061 tgcaggagct ggtggatgtg ctgctgagta cgccgaacat ggaacaccgc accgtcggca
    51121 ttggtcgtct ggacccggaa attgcccgcg acttcagtaa cgttggcccg atggtccgtg
    51181 ccagcggtca cgctcgcgat acccgcgccg atcacccgtt tgttggttat ggcctgctgc
    51241 cgatggaagt gcacagcgag cagggctgcg acgttatttc ccgtctgaaa gtgcgtatca
    51301 atgaagtcta taccgcgctg aacatgatcg actacggtct ggataacctg ccgggcggcc
    51361 cgctgatggt ggaaggcttt acctacattc cgcaccgttt cgcgctgggt tttgccgaag
    51421 cgccgcgcgg cgacgatatc cactggagca tgaccggcga caaccagaag ctgtaccgct
    51481 ggcgctgccg tgccgcgacc tacgcgaact ggccgaccct gcgctacatg ctgcgcggca
    51541 acaccgtttc cgatgcgccg ctgattatcg gtagcctgga cccttgctac tcctgtaccg
    51601 accgcatgac cgtggtcgat gtgcgtaaga agaagagcaa agtggtgccg tacaaagaac
    51661 tcgagcgtta cagcattgag cgtaaaaact cgccgctgaa ataaggaatc gccatgttta
    51721 cctttatcaa aaaagtcatc aaaaccggca cggcgacctc gtcttatccg ctggagccga
    51781 ttgcggttga taaaaacttc cgtggtaagc cagagcagaa cccgcagcag tgcatcggct
    51841 gcgcggcctg cgtcaatgcc tgcccgtcaa acgccttaac ggttgaaact gacctcgcca
    51901 caggagagct tgcgtgggag tttaatctcg ggcgctgcat cttctgtgga cgctgcgaag
    51961 aagtttgccc gacggcggcg attaagctgt cgcaagagta cgaactggcg gtgtggaaga
    52021 aagaagactt cctgcaacag tcccgcttcg cgctgtgcaa ctgtcgcgtc tgcaatcgtc
    52081 ctttcgccgt ccagaaagag atcgactacg ccattgcgct gcttaagcac aatggtgaca
    52141 gccgcgcgga aaaccaccgc gaaagctttg agacttgccc ggaatgtaag cgccagaaat
    52201 gcctggtgcc gtccgaccgt attgaactga ctcgccatat gaaagaggcc atctgatgag
    52261 caatttatta ggcccccgtg acgccaacgg cattccggtc ccgatgacgg tggatgaatc
    52321 catcgccagc atgaaggcgt cgttactgaa aaaaatcaaa cgttctgcct atgtttaccg
    52381 cgtggactgc ggcggctgca acggctgcga aatcgaaatt ttcgccactt tatcgccgct
    52441 gtttgatgca gaacgcttcg gcattaaagt cgttccttca ccgcgtcatg cggatatttt
    52501 actgtttacc ggcgcggtca cccgtgcaat gcgatcccct gcgctgcgtg cgtggcagtc
    52561 cgcgccggac ccgaaaattt gtatctccta cggtgcctgc ggtaacagcg gtggtatttt
    52621 ccacgatctc tactgcgtgt ggggcggtac ggataaaatc gtcccggtag atgtctacat
    52681 tccgggttgc ccgccaacgc ctgccgccac gctgtacggc tttgcaatgg cactcggcct
    52741 gctggagcag aaaattcacg cccgtggccc gggtgagcag gatgaacaac cggcggaaat
    52801 cctgcatggc gatatggtgc agccgctgcg tgtgaaagtg gatcgcgaag cacgccgcct
    52861 ggcaggttat cgttacggtc gtcagattgc cgatgacttc ctgacacagt tagggcaggg
    52921 cgaagaacag gttgcacgct ggctggaagc ggaaaacgat ccgcgtctga acgagattgt
    52981 cagccatctg aatcatgttg tagaagaggc gcgtatccga tgagtgaaaa ggtggtgttc
    53041 agtcaactga gccgtaaatt tattgatgag aacgatgcca cgcccgccga ggcgcagcag
    53101 gtggtctatt acagcctggc gattggtcac caccttgggg ttatcgattg cctggaagcg
    53161 gcgctcacct gcccgtggga tgaatatctg gcatggattg ccactctgga ggcgggcagc
    53221 gaagcccgcc gcaaaatgga aggcgtgccg aaatatggtg agatcgtcat cgacattaac
    53281 catgtgccga tgctggccaa cgcattcgat aaagcccggg tagcgcaaac ttcgcagcag
    53341 caggaatgga gtacaatgct gctaagtatg ctgcatgata ttcatcagga aaacgccatc
    53401 tatttgatgg tgaggagact gcgtgactga cgttttactc tgtgttggca atagcatgat
    53461 gggcgatgat ggcgcaggcc cgctgctggc ggaaaagtgc gccgccgcgc cgaaaggtaa
    53521 ctgggtggtg attgacggcg gtagtgcacc ggaaaacgac atcgtcgcca tccgtgaact
    53581 gcgccctacg cgactgctga ttgtcgacgc cactgatatg gggctaaacc ccggcgagat
    53641 ccgcatcatc gacccggatg atatcgccga gatgtttatg atgactaccc ataacatgcc
    53701 gttgaactat cttatcgacc agttgaaaga agacattggc gaagtgattt tcctcggcat
    53761 ccagccggat atcgtcggct tttactaccc gatgacccag ccgattaaag atgcggtaga
    53821 aaccgtttat caacgactgg aaggctggga aggaaatggc ggattcgcgc agttagcggt
    53881 ggaagaagag tagtttttca ataaggaatc aggacaggga tgttcttgat ggggtgaacc
    53941 agctctgatg ccaaatgcta aattgcccga tgcgctgcgc ttatcggg
//
LOCUS       DAPOAV010000021        53653 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.021, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000021 DAPOAV010000000
VERSION     DAPOAV010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 53653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53653
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.021"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            140..2383
                     /gene="pdeF"
                     /locus_tag="RN951_001516"
     CDS             140..2383
                     /gene="pdeF"
                     /locus_tag="RN951_001516"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase
                     PdeF"
                     /protein_id="HDX2526533.1"
                     /translation="MKLNATYIKIRDKWWGLPLFLPSLILPIFAHINTFAHISSGEVF
                     LFYLPLALMISMMMFFSWAALPGITLGIFVRKYAELGFYETLSLTANFIIIIILCWGG
                     YRVFTPRRNNVSHGDTRLISQRIFWQIVFPATLFLILFQFAAFVGLLASRENLVGVMP
                     FNLGTLINYQALLVGNLIGVPLCYFIIRVVRNPFYLRSYYSQLKQQVDAKVTKKEFAL
                     WLLALGALLLLLCMPLNEKSTIFSTNYTLSLLLPLMMWGAMRYGYKLISLLWAVVLMI
                     SIHSYQNYIPIYPGYTTQLTITSSSYLVFSFIVNYMAVLATRQRAVVRRIQRLAYVDP
                     VVHLPNVRALNRALRDAPWSALCYLRIPGMEMLVKNYGIMLRIQYKQKLSHWLSPLLE
                     PGEDVYQLSGNDLALRLNTESHQERITALDSHLKQFRFFWDGMPMQPQIGVSYCYVRL
                     PVNHIYLLLGELNTVAELSIVTNAPENMQRRGAMYLQRELKDKVAMMNRLQQALEHNH
                     FFLMAQPITGMRGDVYHEILLRMKGENDELIGPDSFLPVAHEFGLSSSIDMWVIEHTL
                     QFMAENRAKMPAHRFAINLSPTSVCQARFPVEVSQLLDKYQIEAWQLIFEVTESNALT
                     NVKQAQITLQHLQELGCQIAIDDFGTGYASYARLKNVNADLLKIDGSFIRNIVSNSLD
                     YQIVASICHLARMKKMRVVAEYVENEEIREAVLSLGIDYMQGYLIGKPQPLIDTLNEI
                     EPIRESA"
     gene            complement(2422..3963)
                     /gene="ppx"
                     /locus_tag="RN951_001517"
     CDS             complement(2422..3963)
                     /gene="ppx"
                     /locus_tag="RN951_001517"
                     /EC_number="3.6.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolyphosphatase"
                     /protein_id="HDX2526534.1"
                     /translation="MPIHDKSPRPQEFAAVDLGSNSFHMVIARVVDGAMQIIGRLKQR
                     VHLADGLGPDNMLSEEAMTRGLNCLSLFAERLQGFSPASVCIVGTHTLRQALNATDFL
                     KRAEKVIPYPIEIISGNEEARLIFMGVEHTQPEKGRKLVIDIGGGSTELVIGENFEPI
                     LVESRRMGCVSFAQLYFPGGVINKENFQRARMAAAQKLETLTWQFRIQGWNVAMGASG
                     TIKAAHEVLMEMGEKDGIITPERLEKLVKEVLRHRNFASLSLPGLSEERKTVFVPGLA
                     ILCGVFDALAIRELRLSDGALREGVLYEMEGRFRHQDVRSRTASSLANQYHIDSEQAR
                     RVLDTTMQMYEQWREQQPKLAHPQLEALLRWAAMLHEVGLNINHSGLHRHSAYILQNS
                     DLPGFNQEQQLMMATLVRYHRKAIKLDDLPRFTLFKKKQFLPLIQLLRLGVLLNNQRQ
                     ATTTPPTLTLITDDSHWTLRFPHDWFSQNALVLLDLEKEQEYWEGVAGWRLKIEEEST
                     PEIAA"
     gene            complement(3968..6034)
                     /gene="ppk1"
                     /locus_tag="RN951_001518"
     CDS             complement(3968..6034)
                     /gene="ppk1"
                     /locus_tag="RN951_001518"
                     /EC_number="2.7.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase 1"
                     /protein_id="HDX2526535.1"
                     /translation="MGQEKLYIEKELSWLSFNERVLQEAADKSNPLIERMRFLGIYSN
                     NLDEFYKVRFAELKRRIIISEEQGSNSHSRHLLGKIQSRVLKADQEFDGLYNELLLEM
                     ARNQIFLINERQLSVNQQNWLRHYFKQYLRQHITPILINPDTDLVQFLKDDYTYLAVE
                     IIRGDTIRYALLEIPSDKVPRFVNLPPEAPRRRKPMILLDNILRYCLDDIFKGFFDYD
                     ALNAYSMKMTRDAEYDLVHEMEASLMELMSSSLKQRLTAEPVRFVYQRDMPNALVEVL
                     REKLTISRYDSIVPGGRYHNFKDFINFPNVGKANLVNKPLPRLRHIWFDKAQFRNGFD
                     AIRERDVLLYYPYHTFEHVLELLRQASFDPSVLAIKINIYRVAKDSRIIDSMIHAAHN
                     GKKVTVVVELQARFDEEANIHWAKRLTEAGVHVIFSAPGLKIHAKLFLISRKENGEVV
                     RYAHIGTGNFNEKTARLYTDYSLLTADARITNEVRRVFNFIENPYRPVTFDYLMVSPQ
                     NSRRLLYEMVDREIANAQQGLPSGITLKLNNLVDKGLVDRLYAASSSGVPVNLLVRGM
                     CSLIPNLEGISDNIRAISIVDRYLEHDRVYIFENGGDKKVYLSSADWMTRNIDYRIEV
                     ATPLLDPRLKQRVLDIIDILFSDTVKARYIDKELSNRYVPRGNRRKVRAQLAIYDYIK
                     SLEQPE"
     gene            complement(6205..6843)
                     /gene="purN"
                     /locus_tag="RN951_001519"
     CDS             complement(6205..6843)
                     /gene="purN"
                     /locus_tag="RN951_001519"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HDX2526536.1"
                     /translation="MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLE
                     RARQAGIATHTLIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAG
                     RLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGD
                     TEDDITARVQTQEHAIYPLVISWFADGRLKMHENAAWLDGQRLPPQGYAADE"
     gene            complement(6843..7880)
                     /gene="purM"
                     /locus_tag="RN951_001520"
     CDS             complement(6843..7880)
                     /gene="purM"
                     /locus_tag="RN951_001520"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HDX2526537.1"
                     /translation="MTDKTSLSYKDAGVDIDAGNALVGRIKGVVKKTRRPEVMGGLGG
                     FGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDTIGIDLVAMCVNDLVVQGAEP
                     LFFLDYYATGKLDVDTASAVISGIAEGCLQSGCSLVGGETAEMPGMYHGEDYDVAGFC
                     VGVVEKSEIIDGSKVSDGDVLIALGSSGPHSNGYSLVRKILEVSGCDPQTTELDGKPL
                     ADHLLAPTRIYVKSVLELIEKVDVHAIAHLTGGGFWENIPRVLPDNTQAVIDESSWQW
                     PEVFNWLQTAGNVERHEMYRTFNCGVGMIIALPAPEVDKALALLNANGENAWKIGIIK
                     ASDSEQRVVIE"
     gene            8205..8831
                     /gene="upp"
                     /locus_tag="RN951_001521"
     CDS             8205..8831
                     /gene="upp"
                     /locus_tag="RN951_001521"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HDX2526538.1"
                     /translation="MKIVEVKHPLVKHKLGLMREQDISTKRFRELASEVGSLLTYEAT
                     ADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMDGVLENVPSARISVVGMY
                     RNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLV
                     AAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK"
     gene            8917..10206
                     /gene="uraA"
                     /locus_tag="RN951_001522"
     CDS             8917..10206
                     /gene="uraA"
                     /locus_tag="RN951_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HDX2526539.1"
                     /translation="MTRRAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHINPA
                     TVLLFNGIGTLLYLFICKGKIPAYLGSSFAFISPVLLLLPLGYEVALGGFIMCGVLFC
                     LVSFIVKKAGTGWLDVLFPPAAMGAIVAVIGLELAGVAAGMAGLLPAEGQTPDSKTII
                     ISITTLAVTVLGSVLFRGFLAIIPILIGVLVGYALSFAMGIVDTTPIINAHWFALPTL
                     YTPRFEWFAILTILPAALVVIAEHVGHLVVTANIVKKDLLRDPGLHRSMFANGLSTVI
                     SGFFGSTPNTTYGENIGVMAITRVYSTWVIGGAAIFAILLSCVGKLAAAIQMIPLPVM
                     GGVSLLLYGVIGASGIRVLIESKVDYNKAQNLILTSVILIIGVSGAKVNIGAAELKGM
                     ALATIVGIGLSLIFKLISVLRPEEVVLDAEDADITDK"
     gene            10256..11002
                     /gene="hda"
                     /locus_tag="RN951_001523"
     CDS             10256..11002
                     /gene="hda"
                     /locus_tag="RN951_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA inactivator Hda"
                     /protein_id="HDX2526540.1"
                     /translation="MVNFSRFCEILVEVSLNTPAQLSLPLYLPDDETFASFWPGDNSS
                     LLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVP
                     EVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNL
                     GLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRT
                     LFMTLDQLDRASITAQRKLTIPFVKEILKL"
     gene            complement(11140..11499)
                     /gene="arsC"
                     /locus_tag="RN951_001524"
     CDS             complement(11140..11499)
                     /gene="arsC"
                     /locus_tag="RN951_001524"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311384.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HDX2526541.1"
                     /translation="MTKQVKIYHNPRCSKSRETLNLLKENGVEPEVVLYLETPADAAT
                     LRDLLKMLGMNSARELMRQKEDLYKELNLADSSLSEEALIQAMVDNPKLMERPIVVAN
                     GKARIGRPPEQVLEIVG"
     gene            complement(11520..12983)
                     /gene="bepA"
                     /locus_tag="RN951_001525"
     CDS             complement(11520..12983)
                     /gene="bepA"
                     /locus_tag="RN951_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-barrel assembly-enhancing protease"
                     /protein_id="HDX2526542.1"
                     /translation="MFRQLKKNLVATLIAAMTIGQVAPAFADSADTLPDMGTSAGSTL
                     SIGQEMQMGDYYVRQLRGSAPLINDPLLTQYINSLGMRLVSHANSVKTPFHFFLINND
                     EINAFAFFGGNVVLHSALFRYSDNESQLASVMAHEISHVTQRHLARAMEDQQRSAPLT
                     WVGALGSILLAMASPQAGMAALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFD
                     PQAMPTFLEKLLDQARYSSRPPEILLTHPLPESRLADARNRANQMRPMVVQSSEDFYL
                     AKARTLGMYNSGRNQLTSDLLDEWAKGNVRQQRAAQYGRALQAMEANKYDEARKTLQP
                     LLAAEPGNAWYLDLATDIDLGQNKANEAINRLKNARDLRTNPVLQLNLANAYLQGGQP
                     QEAANILNRYTFNNKDDSNGWDLLAQAEAALNNRDQELAARAEGYALAGRLDQAISLL
                     SSASSQVKLGSLQQARYDARIDQLRQLQERFKPYTKM"
     gene            13196..14257
                     /locus_tag="RN951_001526"
     CDS             13196..14257
                     /locus_tag="RN951_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDX2526543.1"
                     /translation="MLEMLMQWYRRRFSDPEAIALLVILVAGFGIIFFFSGLLAPLLV
                     AIVLAYLLEWPTVRLQSIGCSRRWATSIVLVVFVGILLLMAFVVLPIAWQQGIYLIRD
                     MPGMLNKLSDFAATLPRRYPALMDAGIIDAMAENMRSRMLTMGDSVVKISLASLVGLL
                     TIAVYLVLVPLMVFFLLKDKEQMLNAVRRVLPRNRGLAGQVWKEMNQQITNYIRGKVL
                     EMIVVGIATWLGFLLFGLNYSLLLAVLVGFSVLIPYIGAFVVTIPVVGVALFQFGAGT
                     EFWSCFAVYLIIQALDGNLLVPVLFSEAVNLHPLVIILSVVIFGGLWGFWGVFFAIPL
                     ATLIKAVIHAWPDGQIAQE"
     gene            complement(14295..14519)
                     /locus_tag="RN951_001527"
     CDS             complement(14295..14519)
                     /locus_tag="RN951_001527"
                     /inference="COORDINATES: protein motif:HMM:NF013397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDX2526544.1"
                     /translation="MYRQFVCDSVRHCHSPFCPTPLRQLAHSSADNFPALTVSHFITA
                     NLLPVMLGNIIGGAVLVSICYRAIYLRQES"
     gene            complement(14411..15142)
                     /locus_tag="RN951_001528"
     CDS             complement(14411..15142)
                     /locus_tag="RN951_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001698835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate transporter"
                     /protein_id="HDX2526545.1"
                     /translation="MRNKLSFDLQLSARKAAIAERIASHKIARSKVSVFLMAMSAGVF
                     MAIGFTFYLSVIADAPSSQALTHLVGGLCFTLGFILLAVCGTSLFTSSVMTVMAKSRG
                     VISWRTWLINALLVACGNLAGIACFSLLIWFSGLVMSENAMWGVAVLHCAEGKMHHTF
                     TESVSLGIMCNLMVCLALWMSYCGRSLCDKIVAMILPITLFVASGFEHCIANLFVIPF
                     AIAIRHFAPRPFGNWRTVAQTIFRH"
     gene            complement(15164..17176)
                     /gene="hyfR"
                     /locus_tag="RN951_001529"
     CDS             complement(15164..17176)
                     /gene="hyfR"
                     /locus_tag="RN951_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311380.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HyfR"
                     /protein_id="HDX2526546.1"
                     /translation="MAMSDEAMFAPPQGITIEAVNGMLAERLAQKHGKASLLRAFIPL
                     PPPFSPVQLIELHVLKSNFYYRYHDDGSDVTATVEYQGEMVDYSRHAVLLGSSGMAEL
                     RFIRTHGSRFTPQDCTLFNWLARIITPVLQSWLNDEEQQVALRLLEKDRDHHRVLVDI
                     TNAVLSHLDLDDLIADVAREIHHFFGLASVSMVLGDHRKNEKFSLWCSDLSASHCACL
                     PRNMPGDSVLLTQTLQTRQPTLTHRADDLFLWQRDPLLLLLASNGCESALLIPLTFGN
                     HTPGALLLAHTSSTLFSEENCQLLQHIADRIAIAVGNADAWRSMTDLQESLQQENHQL
                     SEQLLSNLGVGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLS
                     PRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGD
                     LPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRL
                     NVFPLELPPLRDRPEDIPLLAKHFTQKMARHMNRAIDAIPTEALRQLMSWDWPGNVRE
                     LENVIERAVLLTRGNNLNLHLNVRQSRLLPTLNEDSALRSSMAQLLHPTTPENDEEER
                     QRIVQVLRETNGIVAGPRGAATRLGMKRTTLLSRMQRLGISVREVL"
     gene            complement(17206..17619)
                     /gene="hyfJ"
                     /locus_tag="RN951_001530"
     CDS             complement(17206..17619)
                     /gene="hyfJ"
                     /locus_tag="RN951_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416985.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 assembly chaperone HyfJ"
                     /protein_id="HDX2526547.1"
                     /translation="MAEECGEIVFWTLRKKFVASSDEMPEHSSQVMYYSLAIGHHVGV
                     IDCLNVAFRCPLTEYEDWLAQVEEEQARRKMLGVMTFGEIVIDASHTALLTRAFALLA
                     DDATSVWQARSIQFIHLLDEIVQEPAIYLMARKIA"
     gene            complement(17612..18370)
                     /gene="hyfI"
                     /locus_tag="RN951_001531"
     CDS             complement(17612..18370)
                     /gene="hyfI"
                     /locus_tag="RN951_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 catalytic subunit HyfI"
                     /protein_id="HDX2526548.1"
                     /translation="MSPVLTQYVSQPITLDEQTQKMKQHLLQDIRRSAYVYRVDCGGC
                     NACEIEIFAAITPVFDAERFGIKVVSSPRHADILLFTGAVTRAMRMPALRAYESAPDH
                     KICVSYGACGVGGGIFHDLYSVWGGSDTIVPIDVWIPGCPPTPAATIHGFAVALGLLQ
                     QKIHAVDYRDPTGVTMQPLWPQIPPSQRIAIEREARRLAGYRQGREICDRLLRHLSDD
                     PTGNRVNTWLREADDPRLNSIVQQLFRVLRGLHG"
     gene            complement(18367..18906)
                     /gene="hyfH"
                     /locus_tag="RN951_001532"
     CDS             complement(18367..18906)
                     /gene="hyfH"
                     /locus_tag="RN951_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit H"
                     /protein_id="HDX2526549.1"
                     /translation="MLKLLKTIMRAGTATVKYPFAPLEVSPGFRGKPDLMPSQCIACG
                     ACACPANALTIQTDDQQNSRTWQLYLRRCIYCGRCEEVCPTRAIQLTNNFELTVTNKA
                     DLYTRATFHLQRCSRCERPFAPQKTVALAAELLAQQQNAPQNREMLRAQASVCPECKQ
                     RATLINDDTDVPLVAKEQL"
     gene            complement(18916..20631)
                     /gene="hyfG"
                     /locus_tag="RN951_001533"
     CDS             complement(18916..20631)
                     /gene="hyfG"
                     /locus_tag="RN951_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 catalytic subunit HyfG"
                     /protein_id="HDX2526550.1"
                     /translation="MNVNSSSNRGEAILAALKTQFPGAVLDEERQTPEQVTITVKINL
                     LPDVVHYLYYQHDGWLPVLFGNDERTLNGHYAVYYALSMEGAEKCWIVVKALVDADSR
                     EFPSVTPRVPAAVWGEREIRDMYGLIPVGLPDQRRLVLPDDWPEDMHPLRKDAMDYRL
                     RPEPTTDSETYAFINEGNSDARVIPVGPLHITSDEPGHFRLFVDGEQIVDADYRLFYV
                     HRGMEKLAETRMGYNEVTFLSDRVCGICGFAHSVAYTNSVENALGIEVPQRAHTIRSI
                     LLEVERLHSHLLNLGLSCHFVGFDTGFMQFFRVREKSMTMAELLTGSRKTYGLNLIGG
                     VRRDILKEQRLQTLKLVREMRADVSELVEMLLAMPNMEQRTQGIGILDRQIARDYSPV
                     GPLIRGSGFARDLRFDHPYADYGNIPKTLFTFTGGDVFSRVMVRVKETFDSLAMLEFA
                     LDNMPDTPLLTEGFSYKPHAFALGFVEAPRGEDVHWSMLGDNQKLFRWRCRAATYANW
                     PVLRYMLRGNTVSDAPLIIGSLDPCYSCTDRVTLVDVRKRQSKTVPYKEIERYGIDRN
                     RSPLK"
     gene            complement(20621..22201)
                     /gene="hyfF"
                     /locus_tag="RN951_001534"
     CDS             complement(20621..22201)
                     /gene="hyfF"
                     /locus_tag="RN951_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit F"
                     /protein_id="HDX2526551.1"
                     /translation="MSYSVMFALLLLTPLLFSLLCFACRKRGLSATCTVTVLHSLGIT
                     LLLILALWVVQTAADAGEIFAAGLWLHIDGLGGLFLAILGVIGFLTGVYSIGYMRHEV
                     AHGELSPVTLCDYYGFFHLFLFTMLLVVTSNNLIVMWAAIEATTLSSAFLVGIYGQRS
                     SLEAAWKYIIICTVGVAFGLFGTVLVYANAASVMPQAEMAIFWSEVLKQSSLLDPTLM
                     LLAFVFVLIGFGTKTGLFPMHAWLPDAHSEAPSPVSALLSAVLLNCALLVLIRYYIII
                     CQAIGSDFPNRLLLIFGMLSVAVAAFFILVQRDIKRLLAYSSVENMGLVAVALGIGGP
                     LGIFAALLHTLNHSLAKTLLFCGSGNVLLKYGTRDLNVVCGMLKIMPFTAVLFGGGAL
                     ALAGMPPFNIFLSEFMTVTAGLARNHLLIIVLLLLLLTLVLAGLVRMAARVLMAKPPQ
                     AVNRGDLGWLTTSPMVILLVMMLAMGTHIPQPVIRILAGASTIVLSGTHDLPAQRSTW
                     HDFLPSGTASVSEKHSER"
     gene            complement(22206..22856)
                     /gene="hyfE"
                     /locus_tag="RN951_001535"
     CDS             complement(22206..22856)
                     /gene="hyfE"
                     /locus_tag="RN951_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 membrane subunit"
                     /protein_id="HDX2526552.1"
                     /translation="MTGSMIVNNLAGLMMLTSLFVISVKSYRLSCGFYACQSLVLVSI
                     FATLSCLFAAEQLLIWSASAFITKVLLVPLIMTYAARNIPQNIPEKALFGPAMMALLA
                     ALIVLLCAFVVQPVKLPMATGLKPALAVALGHFLLGLLCIVSQRNILRQIFGYCLMEN
                     GSHLVLALLAWRAPELVEIGIATDAIFAVIVMVLLARKIWRTHGTLDVNNLTALKG"
     gene            complement(22868..23975)
                     /locus_tag="RN951_001536"
                     /pseudo
     CDS             complement(22868..23975)
                     /locus_tag="RN951_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001442177.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit D"
     gene            complement(23987..24097)
                     /locus_tag="RN951_001537"
     CDS             complement(23987..24097)
                     /locus_tag="RN951_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoin racemase"
                     /protein_id="HDX2526553.1"
                     /translation="MENLALTTLMLPFIGALVVSFSPQRRAAEWGFYSPH"
     gene            complement(24114..25058)
                     /gene="hyfC"
                     /locus_tag="RN951_001538"
     CDS             complement(24114..25058)
                     /gene="hyfC"
                     /locus_tag="RN951_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311372.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit HyfC"
                     /protein_id="HDX2526554.1"
                     /translation="MRQTLCDGYLVIFALAQAVILLLTPLFTGISRQIRARMHSRRGP
                     GIWQDYRDIHKLFKRQEVAPISSGLMFRLMPWVLISSMLVLAMALPLFITVSPFAGGG
                     DLITLIYLLALFRFFFALSGLDTGSPFAGVGASRELTLGILVEPMLILSLLVLALIAG
                     STHIEMISNTLATGWNSPLTTVLALLACGFACFIEMGKIPFDVAEAEQELQEGPLTEY
                     SGAGLALAKWGLGLKQVVMAALFVALFLLFGRAQELSLACLLTSLVVTLLKVLLIFVL
                     ASIAENTLARGRFLLIHHVTWLGFSLAALAWVFWLTGL"
     gene            complement(25069..27086)
                     /gene="hyfB"
                     /locus_tag="RN951_001539"
                     /pseudo
     CDS             complement(25069..27086)
                     /gene="hyfB"
                     /locus_tag="RN951_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311371.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit B"
     gene            complement(27086..27703)
                     /gene="hyfA"
                     /locus_tag="RN951_001540"
     CDS             complement(27086..27703)
                     /gene="hyfA"
                     /locus_tag="RN951_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit HyfA"
                     /protein_id="HDX2526555.1"
                     /translation="MNRFVVAEPLWCTGCNTCLAACSDVHKTQGLQQHPRLALAKTST
                     ITAPVVCHHCEEAPCLQVCPVNAISQRDDAIQLNESLCIGCKLCAVVCPFGAISASGS
                     RPVNAHAQYVFQAEGSLKDGEENVLPQHALLRWEPGVQTVAVKCDLCDFLPEGPACVR
                     ACPNQALRLITDDSLQRQMKEKQRLAASWFANGGEDPLSLTQEQH"
     gene            complement(27956..28426)
                     /gene="bcp"
                     /locus_tag="RN951_001541"
     CDS             complement(27956..28426)
                     /gene="bcp"
                     /locus_tag="RN951_001541"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HDX2526556.1"
                     /translation="MNPLKAGDIAPKFSLPDQDGEQVNLTDFQGQRVLVYFYPKAMTP
                     GCTVQACGLRDNMDELKKAGVDVLGISTDKPEKLSRFAEKELLNFTLLSDEDHQVCEQ
                     FGVWGEKSFMGKTYDGIHRISFLIDADGKIEHVFDDFKTSNHHDVVLNWLKEHA"
     gene            complement(28426..28998)
                     /locus_tag="RN951_001542"
     CDS             complement(28426..28998)
                     /locus_tag="RN951_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system transcriptional
                     repressor"
                     /protein_id="HDX2526557.1"
                     /translation="MTLSSQHYLVITALGADRPGIVNTITRHVSSCGCNIEDSRLAML
                     GEEFTFIMLLSGSWNAITLIESTLPLKGAELDLLIVMKRTTARPRPPMPASVWVQVDV
                     ADSPHLIERFTALFDAHHMNIAELVSRTQPAENERAAQLHIQITAHSPASADAANIEQ
                     AFKALCTELNAQGSINVVNYSQHDEQDGVK"
     gene            29144..30022
                     /gene="dapA"
                     /locus_tag="RN951_001543"
     CDS             29144..30022
                     /gene="dapA"
                     /locus_tag="RN951_001543"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001311023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDX2526558.1"
                     /translation="MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGT
                     TGESATLNHDEHADVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLT
                     VTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGI
                     KEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMC
                     KLAAEGHFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITD
                     SGRETVRAALKHAGLL"
     gene            30039..31073
                     /gene="bamC"
                     /locus_tag="RN951_001544"
     CDS             30039..31073
                     /gene="bamC"
                     /locus_tag="RN951_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708316.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamC"
                     /protein_id="HDX2526559.1"
                     /translation="MAYSVQKSRLAKVAGVSLVLLLAACSSDSRYKRQVSGDEAYLEA
                     APLAELHAPAGMILPVTSGDYAIPVTNGSGAVGKALDIRPPAQPLALVSGARTQFTGD
                     TASLLVENGRGNTLWPQVVSVLQAKNYTITQRDDAGQTLTTDWVQWNRLDEDEQYRGR
                     YQISVKPQGYQQAVTVKLLNLEQAGKPVADAASMQRYSTEMMNVISAGLDKSATDAAN
                     AAQNRASTTMDVQSAADDTGLPMLVVRGPFNVVWQRLPAALEKVGMKVTDSTRSQGNM
                     AVTYKPLSDSDWQELGASDPGLASGDYKLQVGDLDNRSSLQFIDPKGHTLTQSQNDAL
                     VAVFQAAFSK"
     gene            31286..31999
                     /gene="purC"
                     /locus_tag="RN951_001545"
     CDS             31286..31999
                     /gene="purC"
                     /locus_tag="RN951_001545"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDX2526560.1"
                     /translation="MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFD
                     RKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLV
                     KRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKAND
                     VLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSL
                     GGLIEAYEAVARRLGVQLD"
     gene            32155..32382
                     /gene="vapB"
                     /locus_tag="RN951_001546"
     CDS             32155..32382
                     /gene="vapB"
                     /locus_tag="RN951_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system antitoxin VapB"
                     /protein_id="HDX2526561.1"
                     /translation="METTVFLSNRSQAVRLPKAVALPEDVKKVEIIAIGRTRIITPAG
                     ESWDSWFDGENVSADFMDIRDQPAMQERESF"
     gene            32382..32780
                     /gene="vapC"
                     /locus_tag="RN951_001547"
     CDS             32382..32780
                     /gene="vapC"
                     /locus_tag="RN951_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(fMet)-specific endonuclease VapC"
                     /protein_id="HDX2526562.1"
                     /translation="MLKFMLDTNICIFTIKNKPVHVRERFNLNSGRMCISSVTLMELI
                     YGAEKSQMPERNLAVIEGFVSRLEVLDYDSAAATHTGQIRAELARQGRPVGPFDQMIA
                     GHARSRGLIVVTNNTREFERVAGIRLEDWS"
     gene            32927..33790
                     /locus_tag="RN951_001548"
     CDS             32927..33790
                     /locus_tag="RN951_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HDX2526563.1"
                     /translation="MRWQGRRESDNVEDRRNSSGGPSMGGPGFRLPSGKGGLILLLVV
                     LVAGYYGVDLTGLMTGQPVSQQQSTRSISPNEDEAAKFTSVILATTEDTWGQQFEKMG
                     KTYQQPKLVMYRGMTRTGCGAGQSIMGPFYCPADGTVYIDLSFYDDMKDKLGADGDFA
                     QGYVIAHEVGHHVQKLLGIEPKVRQLQQNATQAEVNRLSVRMELQADCFAGVWGHNMQ
                     QQGVLETGDLEEALNAAQAIGDDRLQQQSQGRVVPDSFTHGTSQQRYSWFKRGFDSGD
                     PAQCNTFGKSI"
     gene            33805..35820
                     /gene="tmcA"
                     /locus_tag="RN951_001549"
     CDS             33805..35820
                     /gene="tmcA"
                     /locus_tag="RN951_001549"
                     /EC_number="2.3.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA cytosine(34) acetyltransferase TmcA"
                     /protein_id="HDX2526564.1"
                     /translation="MAELTALHTLTAQMKREGIRRLLVLSGEEGWCFDHALKLRDALP
                     GDWLWISPQPDAENHCSPSALQTLLGREFRHAVFDARHGFDAAAFAALSGTLKAGSWL
                     VLLLPVWEEWENQPDADSLRWSDCPDPIATPHFVQHLKRVLTADNDAILWRQNQPFSL
                     AHFTPRTDWHPATGAPQPEQQQLLQQLLTMPPGVAAVTAARGRGKSALAGQLISRIAG
                     SAIVTAPAKAATDVLAQFAGEKFRFIAPDALLASDEQADWLVVDEAAAIPAPLLHQLV
                     SRFPRTLLTTTVQGYEGTGRGFLLKFCARFPHLHRFELQQPIRWAQGCPLEKMVSEAL
                     VFDDENFTHTPQGNIVISAFEQTLWRSEPETPLKVYQLLSGAHYRTSPLDLRRMMDAP
                     GQHFLQAAGENEIAGALWLVDEGGLSQQLSQAVWAGFRRPRGNLVAQSLAAHGSNPLA
                     ATLRGRRVSRIAVHPARQREGTGQQLIAGALQYTRDLDYLSVSFGYTGELWRFWHRCG
                     FVLVRMGNHREASSGCYTAMALLPMSNAGKQLAEREHYRLRRDAQALAKWNGETLPVD
                     PLNDAVLSDDDWLELAGFAFAHRPLLTSLGCLLRLLQTSELALPALRGRLQKNVSDAQ
                     LCTTLKLSGRKMLLVRQREEAAQALFALNDVRTERLRDRITQWQFFH"
     gene            35894..36592
                     /gene="ypfH"
                     /locus_tag="RN951_001550"
     CDS             35894..36592
                     /gene="ypfH"
                     /locus_tag="RN951_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311362.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HDX2526565.1"
                     /translation="MKHDHFVVQSPDKPAQQLLLLFHGVGDNPVAMGEIGSWFAPLFP
                     DALVVSVGGAEPSGNPAGRQWFSVQGITEDNRQARVDAIMPTFIETVRYWQKQSGVGA
                     NATALIGFSQGAIMALESIKAEPGLASRVIAFNGRYASLPETASTATTIHLIHGGEDP
                     VIDLAHAVAAQEALISAGGDVTLDIVEDLGHAIDNRSMQFALDHLRYTIPKHYFDEAL
                     SGGKPGDDDVIEMM"
     gene            complement(36702..36902)
                     /locus_tag="RN951_001551"
     CDS             complement(36702..36902)
                     /locus_tag="RN951_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpfN family protein"
                     /protein_id="HDX2526566.1"
                     /translation="MDWLAKYWWILVIVFLVGVLLNVIKDLKRVDHKKFLANKPELPP
                     HRDFNDKWDDDDDWPKKDQPKK"
     gene            complement(36930..38057)
                     /gene="dapE"
                     /locus_tag="RN951_001552"
     CDS             complement(36930..38057)
                     /gene="dapE"
                     /locus_tag="RN951_001552"
                     /EC_number="3.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020078199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinyl-diaminopimelate desuccinylase"
                     /protein_id="HDX2526567.1"
                     /translation="MSCPVIELTQQLIRRPSLSPDDAGCQALLIERLQAIGFTVERMD
                     FADTQNFWAWRGQGETLAFAGHTDVVPPGDADRWINPPFEPTIRDGMLFGRGAADMKG
                     SLAAMVVAAERFVAQHPNHTGRLAFLITSDEEASAHNGTVKVVEALMSRNERLDYCLV
                     GEPSSIEVVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFLNELVAIE
                     WDQGNEFFPATSMQIANIQAGTGSNNVIPGELFVQFNFRFSTELTDEMIKAQVLALLE
                     KHQLRYTVDWWLSGQPFLTARGKLVDAVVNAVEHYNEIKPQLLTTGGTSDGRFIARMG
                     AQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA"
     gene            complement(38061..38417)
                     /locus_tag="RN951_001553"
     CDS             complement(38061..38417)
                     /locus_tag="RN951_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsC family reductase"
                     /protein_id="HDX2526568.1"
                     /translation="MVTLYGIKNCDTIKKARRWLEANNIDYRFHDYRVDGLDSELLNG
                     FINELGWEALLNTRGTTWRKLDETTRNKITDAASAAALMTEMPAIIKRPLLCAPGKPM
                     LLGFSDSSYQQFFHEV"
     gene            38798..38857
                     /gene="ypfM"
                     /locus_tag="RN951_001554"
     CDS             38798..38857
                     /gene="ypfM"
                     /locus_tag="RN951_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YpfM"
                     /protein_id="HDX2526569.1"
                     /translation="MIERELGNWKDFIEVMLRK"
     gene            complement(38956..42069)
                     /gene="acrD"
                     /locus_tag="RN951_001555"
     CDS             complement(38956..42069)
                     /gene="acrD"
                     /locus_tag="RN951_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease AcrD"
                     /protein_id="HDX2526570.1"
                     /translation="MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVR
                     VTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSGTGQASVTLSFKAGTDPDE
                     AVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS
                     NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQ
                     LGGTPSVDKQALNATINAQSLLQTPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYD
                     YLSRFNGKPASGLGVKLASGANEMATAELVLNRLDELAQYFPHGLEYKVAYETTSFVK
                     ASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNT
                     LTMFAMVLAIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLS
                     AVFVPMAFFGGTTGAIYRQFSITIVAAMVLSVLVAMILTPALCATLLKPLKKGEHHGQ
                     KGFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLPTSFLPLE
                     DRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYFTHEKDNIMSVFATVGSGPGGNGQNVA
                     RMFIRLKDWSERDSKTGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDME
                     LQDHAGAGHDALMAARNQLLVLAAENPELTRVRHNGLDDSPQLQIDIDQRKAQALGVD
                     IDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVP
                     FSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLE
                     WTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLAT
                     WMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEATLHACRQRLRPI
                     LMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRF
                     PLKPRPE"
     gene            complement(42233..43933)
                     /gene="narQ"
                     /locus_tag="RN951_001556"
     CDS             complement(42233..43933)
                     /gene="narQ"
                     /locus_tag="RN951_001556"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarQ"
                     /protein_id="HDX2526571.1"
                     /translation="MIVKRPVSASLARAFFYIVLLSILSTGIALLTLASSLRDAEAIN
                     IAGSLRMQSYRLGYDLQSGSPQLNAHRQLFQQALHSPVLTNLNVWYVPEAVKTRYAHL
                     NANWLEMNNRLSKGDLPWYQANINNYVNQIDLFVLALQHYAERKMLLVVAISLAGGIG
                     IFTLVFFTLRRIRHQVVAPLNQLVTASQRIEHGQFDSPPLDTSLPNELGLLAKTFNQM
                     SSELHKLYLSLEASVEEKTRDLHEAKRRLEVLYQCSQALNTSQIDVHCFRHILQIVRD
                     NEAAEYLELNVGENWRISEGQPNPELPMQILPVTMQETVYGELHWQNSHVSSSEPLLN
                     SVSSMLGRGLYFNQAQKHFQQLLLMEERATIARELHDSLAQVLSYLRIQLTLLKRSIP
                     EDNATAQSIMADFSQALNDAYRQLRELLTTFRLTLQQADLPSALREMLDTLQNQTSAK
                     LTLDCRLPTLALDAQMQVHLLQIIREAVLNAMKHANASEIAVSCVTAPDGNHTVYIRD
                     NGIGIGEPKEPEGHYGLNIMRERAERLGGTLTFSQPSGGGTLVSISFRSAEGEESQLM
                     "
     gene            44139..46118
                     /gene="aegA"
                     /locus_tag="RN951_001557"
     CDS             44139..46118
                     /gene="aegA"
                     /locus_tag="RN951_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent uric acid utilization protein
                     AegA"
                     /protein_id="HDX2526572.1"
                     /translation="MNRFIMANSQQCLGCHACEIACVMAHNDEQHVLSQHHFHPRITV
                     IKHQQQRSAVTCHHCEDAPCARSCPNGAISHVDDSIQVNQQKCIGCKSCVVACPFGTM
                     QIVLTPVAAGKVKATAHKCDLCAGRENGPACVENCPADALQLVTDVALSGMAKSRRLR
                     TARQEHQPWHASTAAQEMPVMSKVEQMQATPARGEPDKLAIEARKTGFDEIYLPFRAD
                     QAQREASRCLKCGEHSVCEWTCPLHNHIPQWIELVKAGNIDAAVELSHQTNTLPEITG
                     RVCPQDRLCEGACTIRDEHGAVTIGNIERYISDQALAKGWRPDLSHVTKVDKRVAIIG
                     AGPAGLACADVLTRNGVAVTVYDRHPEIGGLLTFGIPSFKLDKSLLARRREIFSAMGI
                     HFELNCEVGKDVSLDSLLEQYDAVFVGVGTYRSMKAGLPNEDAPGVYDALPFLIANTK
                     QVMGLEELPEEPFINTAGLNVVVLGGGDTAMDCVRTALRHGASNVTCAYRRDEANMPG
                     SKKEVKNAREEGANFEFNVQPVALELNEQGHVCGIRFLRTRLGEPDAQGRRRPVPIEG
                     SEFVMPADAVIMAFGFNPHGMPWLESHGVTVDKWGRIIADVESQYRYQTTNPKIFAGG
                     DAVRGADLVVTAMAEGRHAAQGIIDWLGVKSVKSH"
     gene            46186..46761
                     /gene="nudK"
                     /locus_tag="RN951_001558"
     CDS             46186..46761
                     /gene="nudK"
                     /locus_tag="RN951_001558"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose pyrophosphatase NudK"
                     /protein_id="HDX2526573.1"
                     /translation="MTQQITLIKDKILSDNYFTLHNITYDLTRKDGEVIRHKREVYDR
                     GNGATILLYNAKKKTVVLIRQFRVATWVNGNESGQLIETCAGLLDNDEPKVCIRKEAI
                     EETGYEVGEVRKLFELYMSPGGVTELIHFFIAEYSDNQRANAGGGVEDEDIEVLELPF
                     SQALEMIKTGEIRDGKTVLLLNYLQTSHLMD"
     gene            46887..47930
                     /locus_tag="RN951_001559"
     CDS             46887..47930
                     /locus_tag="RN951_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1176 domain-containing protein"
                     /protein_id="HDX2526574.1"
                     /translation="MRYRIFLLFFFALLPTSLVWAAPAQRAFSDWQVTCNNQNFCVAR
                     NTGDHNGLVMTLSRSAGAHTDAVLRIERGGLKSPDASEGEIAPRLLLDGEPLALSGDK
                     WRISPWLLVTDDTATITAFLQMIQEGKAITLRDGNQTISLSGLKAALLFIDAQQKRVG
                     SETAWIKKGDEPPLSVPPAPALKEVAVVNPTPTPLSLEERNDLLDYGNWRMNGLRCSL
                     DPLRREVNVTALTDDKALMMISCEAGAYNTIDLAWIVSRKKPLASRPVRLRLPFNNGQ
                     ETNELELMNATFDEKSRELVTLAKGRGLSDCGIQARWRFDGQRFRLVRYAAEPTCDNW
                     HGPDAWPTLWITR"
     gene            complement(48026..50029)
                     /gene="tkt"
                     /locus_tag="RN951_001560"
     CDS             complement(48026..50029)
                     /gene="tkt"
                     /locus_tag="RN951_001560"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDX2526575.1"
                     /translation="MSRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFL
                     KHNPTDPTWYDRDRFILSNGHASMLLYSLLHLTGYDLPLEELKNFRQLHSKTPGHPEI
                     GYTPGVETTTGPLGQGLANAVGLAIAERTLAAQFNQPDHEIVDHFTYVFMGDGCLMEG
                     ISHEVCSLAGTLGLGKLIGFYDHNGISIDGETEGWFTDDTAKRFEAYHWHVIHEIDGH
                     DPQAVKEAILEAQSVKDKPSLIICRTVIGFGSPNKAGKEEAHGAPLGEEEVALARQKL
                     GWHHPPFEIPKKIYHAWDAREKGEKAQQSWNEKFAAYKKAHPQLAEEFTRRMSGGLPK
                     DWEKTTQKYINELQANPAKIATRKASQNTLNAYGPMLPELLGGSADLAPSNLTIWKGS
                     VSLKEDPAGNYIHYGVREFGMTAIANGIAHHGGFVPYTATFLMFVEYARNAARMAALM
                     KARQIMVYTHDSIGLGEDGPTHQAVEQLASLRLTPNFSTWRPCDQVEAAVGWKLAVER
                     HNGPTALILSRQNLAQVERTPDQVKEIARGGYVLKDSGGKPDIILIATGSEMEITLQA
                     AEKLAGEGRNVRVVSLPSTDIFDAQDEEYRESVLPSNVAARVAVEAGIADYWYKYVGL
                     KGAIVGMTGYGESAPADKLFPFFGFTAENIVAKAHKVLGVKGA"
     gene            complement(50049..50999)
                     /gene="tal"
                     /locus_tag="RN951_001561"
     CDS             complement(50049..50999)
                     /gene="tal"
                     /locus_tag="RN951_001561"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HDX2526576.1"
                     /translation="MNELDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGL
                     SQYEHLIDDAIAWGKKNGKTQEQQVVAACDKLAVNFGAEILKIVPGRVSTEVDARLSF
                     DKEKSIEKARHLVDLYQQQGVEKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSF
                     AQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHHYE
                     TIVMGASFRRTEQILALTGCDRLTIAPNLLKELQEKVSPVVRKLIPPSQTFPRPAPMS
                     EAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL"
     gene            51288..53567
                     /gene="maeB"
                     /locus_tag="RN951_001562"
     CDS             51288..53567
                     /gene="maeB"
                     /locus_tag="RN951_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxaloacetate-decarboxylating
                     malate dehydrogenase"
                     /protein_id="HDX2526577.1"
                     /translation="MDDQLKQSALDFHEFPVPGKIQVSPTKPLATQRDLALAYSPGVA
                     APCLEIEKDPLKAYKYTARGNLVAVISNGTAVLGLGNIGALAGKPVMEGKGVLFKKFA
                     GIDVFDIEVDELDPDKFIEVVAALEPTFGGINLEDIKAPECFYIEQKLRERMNIPVFH
                     DDQHGTAIISTAAILNGLRVVEKNISDVRMVVSGAGAAAIACMNLLVALGLQKHNIVV
                     CDSKGVIYQGREPNMAETKAAYAVVDDGKRTLDDVIEGADIFLGCSGPKVLTQEMVKK
                     MARAPMILALANPEPEILPPLAKEVRPDAIICTGRSDYPNQVNNVLCFPFIFRGALDV
                     GATAINEEMKLAAVRAIAELAHAEQSEVVASAYGDQDLSFGPEYIIPKPFDPRLIVKI
                     APAVAKAAMESGVATRPIADFDVYIDKLTEFVYKTNLFMKPIFSQARKAPKRVVLPEG
                     EEARVLHATQELVTLGLAKPILIGRPNVIEMRIQKLGLQIKAGVDFEIVNNESDPRFK
                     EYWTEYFQIMKRRGVTQEQAQRALISNPTVIGAIMVQRGEADAMICGTVGDYHEHFSV
                     VKNVFGYRDGVHTAGAMNALLLPSGNTFIADTYVNDEPDAEELAEITLMAAETVRRFG
                     IEPRVALLSHSNFGSSDCPSSSKMRQALELVRDRAPDLMIDGEMHGDAALVEAIRNDR
                     MPDSPLKGSANILVMPNMEAARISYNLLRVSSSEGVTVGPVLMGVAKPVHVLTPIASV
                     RRIVNMVALAVVEAQTQPL"
BASE COUNT        13029 a        13864 c        14115 g        12645 t
ORIGIN      
        1 gatatatatc aattggaact ttcatatgac acttagaatc aatgctctct atagtgatga
       61 ataatcatca ttcgaagtca ggtgggatgc ctgtctgaat acacctcctt caggatgtgg
      121 gggattctgc tgagcatcta tgaaactgaa tgcaacttat ataaaaatac gtgataaatg
      181 gtgggggctt ccgctgttcc tgccttcttt aatcttgccc attttcgccc acattaatac
      241 tttcgcgcat atttcttccg gtgaggtttt tctcttttat ctgcctttgg cactgatgat
      301 cagcatgatg atgtttttca gctgggcggc attgccaggg atcaccttag ggatttttgt
      361 ccgcaaatat gcagagctgg gtttttacga aacgctctca ttaacggcta attttattat
      421 cattatcatt ctctgttggg gcggttacag ggtctttact ccccggcgta acaacgtttc
      481 acatggtgat acccgtttaa tttcccagcg tatattctgg cagatagtgt ttcctgcaac
      541 gctgtttctg atacttttcc agtttgctgc atttgtagga ttgctggcga gcagagaaaa
      601 tctggtcggt gtcatgcctt ttaacctcgg gactttaatc aattatcagg ccttactggt
      661 gggtaatctg atcggtgtcc cgctgtgcta cttcatcatt cgggtagtgc gaaatccatt
      721 ttatttacgt agctattatt cgcaattaaa acagcaggtt gatgccaaag tcaccaaaaa
      781 agagttcgcg ctctggctac tggcattagg tgctttattg ttgctgttat gcatgccgtt
      841 aaatgaaaaa agcacaattt ttagcaccaa ttataccttg tcattattgc tgcccctgat
      901 gatgtgggga gcgatgcgct atggttataa gctgatttcg ctgctctggg cggtcgtgtt
      961 gatgatcagc atccacagct atcaaaatta cattcccatt tatcctggct ataccacgca
     1021 gctgaccata acctcctcca gttatctggt attctctttt attgtcaatt atatggctgt
     1081 actggcaact cgtcagcgag cggtagtcag acgcattcag cggcttgcgt atgtggaccc
     1141 ggtggttcat ctgccaaatg ttcgcgccct gaatcgcgcg ttgcgtgatg ccccctggtc
     1201 tgcgctttgt tatttacgca tccctggcat ggaaatgctg gttaagaact atggcatcat
     1261 gctgcggatt caatacaagc aaaaactttc tcactggctg tcacccttgc tggaaccggg
     1321 tgaagatgtt tatcagcttt cgggtaacga tctcgcgctg cggctgaata cagaatcgca
     1381 ccaggagcgc attaccgcac tggatagcca tctcaagcaa tttcgtttct tttgggatgg
     1441 catgccgatg caaccgcaga ttggcgtcag ttactgctat gtgcgcttgc cagtgaatca
     1501 tatctacctg ctgctgggag agctaaatac ggtcgccgaa ctttccatcg tgaccaacgc
     1561 cccggaaaat atgcagcgtc gcggggcaat gtatttgcaa cgcgaattga aagataaagt
     1621 cgcgatgatg aatcgactac agcaggcgct ggaacacaac cattttttcc tgatggccca
     1681 gccgattacc ggtatgcgtg gtgatgttta ccatgaaatt cttctgcgca tgaaaggtga
     1741 gaatgatgaa ctgatcggcc ccgatagctt cttgccggtc gcgcacgaat ttggtttatc
     1801 gtcgagtatc gacatgtggg tcattgagca tacgctgcaa tttatggctg aaaacagagc
     1861 gaagatgccc gctcaccgtt ttgctattaa tctgtctcca acctcggtat gtcaggctcg
     1921 ttttcctgtt gaagtcagtc agttgctgga taaatatcag attgaagcgt ggcaacttat
     1981 ttttgaagtc accgaaagta atgctctgac caatgttaag caggcgcaaa tcaccttgca
     2041 gcatcttcag gaattaggct gccagattgc gattgatgat ttcggcaccg gctacgccag
     2101 ctatgcgcgg cttaaaaatg tgaatgccga tctgcttaaa attgacggca gttttatccg
     2161 caatattgtg tcaaatagtc tggattatca gatagtggca tcgatttgcc acctggcgcg
     2221 aatgaagaaa atgcgggtag tggcagagta cgttgaaaac gaagagatcc gcgaggcggt
     2281 gctctctttg gggatcgatt atatgcaggg ttatcttatt ggtaagccgc aaccgttaat
     2341 tgatacgctg aatgaaatcg aacccattcg cgaaagtgcc tgaataatgc gggccgacat
     2401 ttctcgtcgg cccgcaaagc attaagcggc gatttcaggt gtactttctt cttcaatttt
     2461 caaccgccag ccagccacgc cttcccagta ttcttgctcc ttttccagat caagcagtac
     2521 cagcgcattc tgactaaacc agtcatgcgg gaaacgcagt gtccagtgac tgtcatcagt
     2581 aatcagtgtc aatgttggcg gtgtggtggt tgcctgacgt tgattgttta gtaatacgcc
     2641 aaggcgcaat agctgtatca gtggcaggaa ctgtttcttc ttaaacaagg taaagcgcgg
     2701 cagatcgtcg agtttaatcg ctttacggtg atagcgcacc agtgtcgcca tcatcagctg
     2761 ctgttcctga ttaaaacccg gcaagtcact gttttgtaga atataagcgg agtggcgatg
     2821 caaaccgctg tggttgatat tcaacccgac ctcatgcagc atggcggccc atcgcagtag
     2881 cgcctccagc tgcggatgcg ccagcttcgg ttgctgttcc cgccactgtt cgtacatttg
     2941 catagtggta tccagcactc gtcgggcctg ttcgctgtcg atgtgatact ggttggcgag
     3001 gctgctggcg gtacgactac gcacatcctg atgacggaaa cgtccttcca tttcatacag
     3061 tacgccttca cgtaaagccc cgtcagaaag gcgcagttca cggatggcta aagcatcaaa
     3121 cacaccgcat aaaatcgcca gtccaggaac gaagactgtt ttccgctctt cggaaagacc
     3181 cggtaaactc agcgatgcga aattacggtg acgtaaaact tcttttacca gtttttccag
     3241 acgttccggg gtaattatcc cgtctttctc gcccatttcc attaatactt catgggcggc
     3301 ttttatggta ccggaagcgc ccattgccac gttccagccc tgaatacgga attgccaggt
     3361 taaagtttcc agtttttgtg ctgccgccat gcgagcgcgc tggaaattct ctttattgat
     3421 gaccccgcca gggaaataaa gctgggcaaa gctgacacaa cccatccggc ggctttcaac
     3481 gagaataggt tcgaaatttt caccaatcac cagttccgta gatccgccgc caatatcaat
     3541 aaccagtttg cgaccttttt ccggttgggt atgttccact cccataaaaa tcagacgggc
     3601 ttcttcatta ccggaaataa tttcaatcgg gtagggaatg accttttccg cgcgtttcag
     3661 aaagtcagtg gcgttcagcg cctgacgcag cgtatgggta ccaactatac agacgctggc
     3721 aggagaaaac ccttgtagcc gttcggcaaa aagcgacaga cagttcaaac cgcgcgtcat
     3781 tgcctcttca ctcaacatat tatctggccc caggccgtcc gccagatgca cccgctgttt
     3841 caggcggcca ataatctgca tggcaccatc taccacacgg gctatgacca tgtgaaaact
     3901 gtttgaacca agatcgaccg cagcaaactc ctgcggacga ggggatttat cgtgtattgg
     3961 catagggtta ttcaggttgt tcgagtgatt tgatgtagtc ataaatcgcc aactgcgccc
     4021 gtactttgcg gcgattgccg cggggaacgt agcgattact gagttcttta tcgatataac
     4081 gagctttgac cgtatcgctg aacaatatgt cgatgatgtc cagcacccgc tgcttcaggc
     4141 gcggatcgag cagcggcgtc gccacttcaa tacgataatc aatattgcgc gtcatccagt
     4201 cggcggaaga aaggtagacc tttttatcgc cgccattttc aaaaatataa acccggtcat
     4261 gttcaaggta acggtcaaca atactgatgg cacgaatgtt gtcgctaatg ccttccagat
     4321 tggggatcag cgaacacatt ccgcgaacca gcagattaac cggtacgccg gagctggagg
     4381 ccgcatacag acgatcaacc aggcctttat cgacaaggtt atttagcttc agggtgatac
     4441 cgctgggcag cccttgctgc gcgttggcga tttcgcggtc taccatttca tataacagac
     4501 ggcgagagtt ttgcggtgac accattaaat aatcaaatgt caccgggcgg tatgggtttt
     4561 caataaagtt aaatacccgc cgtacttcgt tggtgatacg cgcatcggcg gtcagcaatg
     4621 aatagtcagt ataaagacgc gcggtttttt cgttaaagtt cccggtcccg atgtgtgcgt
     4681 aacgcaccac ttcaccgttt tcttttcgtg aaatcaggaa cagtttggcg tgaattttca
     4741 gccccggcgc agagaagata acgtgcacgc ctgcttcggt caggcgcttc gcccagtgaa
     4801 tgttagcttc ttcgtcgaaa cgcgcctgta actcaaccac cacggtgact ttcttaccgt
     4861 tatgtgcggc gtggatcatc gagtcgatga tgcgtgaatc tttcgccacg cggtaaatgt
     4921 taattttaat cgccagtacg ctcgggtcga acgaagcctg acgcagcagt tccagcacat
     4981 gctcaaaggt gtgataagga taatagagca acacatcgcg ttcgcgaatg gcatcaaaac
     5041 cattgcggaa ctgggcttta tcaaaccaaa tatggcgtaa acgcggcagt ggtttgttca
     5101 ccagattggc tttgccgaca ttggggaaat taataaagtc tttaaaatta tgataacgac
     5161 cgccggggac gatggagtcg tagcgggaaa tagtcagttt ttcgcgtaac acttcaacca
     5221 gcgcattggg catatcgcgc tgataaacaa aacgcaccgg ctcagcagtt aaacgctgct
     5281 tgagactgga agacatcaac tccatcaggc tggcttccat ctcatgcact aaatcgtatt
     5341 cggcatcgcg ggtcatcttc attgaatagg cattcagcgc gtcataatca aagaagcctt
     5401 tgaaaatatc atcaaggcag taacgcagaa tgttatccag aagaatcatc ggcttgcgtc
     5461 gacgcggcgc ttctggcggt aaattcacaa agcgcggcac tttatctgat gggatctcca
     5521 gcagcgcgta acggatggta tcgccacgga taatttccac cgccagatag gtgtaatcat
     5581 ctttcaggaa ctgcactaag tcagtgtcag gattgattaa aatcggcgta atgtgctgac
     5641 gcagatactg cttaaaataa tgacgcagcc agttttgttg attgacggag agctggcgtt
     5701 cattaatcag gaagatctgg ttacgcgcca tctccagcag cagctcgttg tagaggccgt
     5761 cgaattcctg atcggctttc agcacccggg actgaatttt gcccagtaaa tggcgggaat
     5821 gagagttgga gccttgttct tcgctaataa tgatgcgtcg cttcagttca gcgaagcgga
     5881 ctttatagaa ctcatcaagg ttattggaat agatccccag gaaacgcatc ctttcaatca
     5941 gcgggttaga tttgtccgcc gcttcctgaa gcacgcgttc attgaacgat aaccaactga
     6001 gctctttttc gatgtatagc ttttcctgac ccattaccac ttttactccg ttttattcac
     6061 gggacactgc ctggatatta tggcgagcaa tattggcaga tgtccaacta tgccagaaaa
     6121 gggggaaaaa aactgctgga gcttgcgatt tacaggtgaa ttgaaaaacg ccagcggcag
     6181 agctggcgct ttaactacgg ggcattactc gtcggcagcg tagccctgcg gcggcagacg
     6241 ttgaccatcc agccacgcgg cgttttcgtg cattttcaga cgaccatcgg caaaccagct
     6301 aatcaccagt ggataaatag cgtgttcctg ggtttgcacg cgggcggtga tgtcatcttc
     6361 cgtatcacca gcaaataccg ggactttcgc ctgtaaaata accgggccac cgtccagttc
     6421 atcggtgacg aaatgcaccg atgtaccgtg ctcttcatca ccattttcca gcgcctgacg
     6481 atgggtgtgt aatccgggat atttcggcag cagagaaggg tgaatgttca gcaaacgccc
     6541 ggcatagtgg gagacaaacg ccgggctgag aatgcgcata aaaccagcca gcacgaccac
     6601 atcgggtgcg tacatgtcga tttcatgaat caactcccgg tcataggcct cacgactgtc
     6661 aaacgcgctg gcgatgagcg tatgcgttgc aatacccgcc tggcgggcgc gttcaaggcc
     6721 gaacgcgtcg gccttattgc tgaaaactgc ccgtacggtg cctttaattt tgttggtttt
     6781 acaggcgtca ataattgcct gtaaattact tccgttgccg gaaataagca ccacaatatt
     6841 cattattcga taaccacgcg ttgttcggaa tcagaggctt tgatgatacc gattttccac
     6901 gcgttttcac cgttggcatt gagtagggcg agggctttgt ccacttccgg agcaggcagg
     6961 gcaataatca tcccgacgcc gcagttgaag gtgcgataca tttcatggcg ctcaacgtta
     7021 cctgccgttt gcagccagtt gaacacttcc ggccactgcc aggaagattc atcaatcact
     7081 gcctgggtat tatctggcaa tacgcgcgga atgttttccc agaagccgcc gccggtcagg
     7141 tgcgcaatgg catgcacatc gaccttttca atcaactcca gcactgactt cacgtaaatg
     7201 cgggtcggtg ccagcagatg atcggctaat ggcttaccat caagttcggt ggtttgcgga
     7261 tcacaaccgc tgacttcaag aattttgcgc accagcgaat agccgttcga gtgcggaccg
     7321 ctggaaccga gtgcaatcag cacatcgccg tcgctgactt tagagccgtc gatgatttct
     7381 gatttttcta ccacgccaac gcagaaaccc gcgacatcgt aatcttcacc gtgatacatc
     7441 cccggcattt ctgccgtttc gccacccacc agtgaacagc ccgattgcag acatccttcc
     7501 gcaatgccgc tgatcaccgc tgaagcggta tcaacatcca gttttccggt tgcgtaatag
     7561 tcgaggaaaa acagcggttc tgcaccttgc accaccaggt cattaacgca catggcgacc
     7621 agatcaatac caatggtgtc gtgacgtttt aagtccattg ccagacgcag cttggtacct
     7681 acgccgtcag tgccggaaac cagcacgggt tcacgatatt tttgcggcaa tgcacacagc
     7741 gcaccgaagc cgcccagacc gcccatcact tccggacgac gcgttttctt cactacgcct
     7801 ttgattcttc caaccagagc attacccgcg tcaatatcaa caccggcatc tttgtagcta
     7861 agagaggttt tatcggtcac tgcttgggtc cccacgcgtt acttgcggta gaaaaataaa
     7921 attcggcgca attctaacag ggaaagcaaa cgtttgcgag actgctttac acaacctttt
     7981 tgcacgtctt ttccccagac gcgcggcgaa agaagacttg tgccagggca aaggttagtt
     8041 ttcggatgga ataatcttct ttcataacca tttgaatata aaataacttt atctcaaacc
     8101 gttatcattt tgactaaagt caacgaaaag aatattgccg ccttgaagaa aggaggtata
     8161 atccgtcgat tttttttgtg gctgcccctc aaaggagaaa gagtatgaag atcgtggaag
     8221 tcaaacaccc actcgtcaaa cacaagctgg gactgatgcg tgagcaagat atcagcacca
     8281 agcgctttcg cgaactcgct tccgaagtgg gtagcctgct gacttacgaa gcgaccgccg
     8341 acctcgaaac ggaaaaagta actatcgaag gctggaacgg cccggtagaa atcgaccaga
     8401 tcaaaggtaa gaaaattacc gttgtgccaa ttctgcgtgc cggtctgggg atgatggacg
     8461 gtgtgctgga aaatgttccg agcgcgcgca tcagcgttgt cggtatgtac cgtaatgaag
     8521 aaacgctgga gccggtaccg tacttccaga aactggtttc taacatcgat gagcgtatgg
     8581 cgctgatcgt tgacccaatg ctggcaactg gtggttccgt tatcgcgacc atcgacctgc
     8641 tgaaaaaagc gggctgcagc agcatcaaag ttctggtgct ggtagctgcg ccagaaggta
     8701 tcgctgcgct ggaaaaagcg cacccggacg tcgaactgta taccgcatcg attgaccagg
     8761 gactgaacga gcacggatac attattccgg gcctcggcga tgccggtgac aaaatctttg
     8821 gtacgaaata aagaataaaa ataattaaag ccgactttaa gagtcggctt ttttttgagt
     8881 aaagcgccta taacacataa tacagaggat aatactatga cgcgccgtgc tatcggggtg
     8941 agtgaaagac cgccactttt acagacaatc ccgcttagtt tgcaacattt gttcgccatg
     9001 tttggtgcaa ccgtcctggt gcccgtctta tttcatatta acccggcgac tgtactgtta
     9061 tttaacggta ttggaacgct gctgtatctc ttcatctgta aagggaaaat tccggcttat
     9121 cttggttcca gctttgcctt tatttcaccg gtattgttac tgttgccgtt agggtatgaa
     9181 gtcgcgctgg gcggctttat tatgtgcggc gtgctgttct gcctggtttc ttttatcgtg
     9241 aagaaagcgg ggaccggctg gctggacgtg ctgtttccac ctgcggcaat gggcgcaatc
     9301 gttgccgtca tcggtctgga gctggcgggc gtagctgccg gtatggcggg tttactcccg
     9361 gctgaagggc aaacgccaga ctccaaaacc atcatcatct ctattaccac cctggcggtc
     9421 acggttttag gttccgtgct gtttcgtggt ttcctggcaa ttatcccgat tttaattggc
     9481 gtgctggtgg gctacgcgct ctctttcgca atgggaattg tcgataccac gccgattatt
     9541 aatgctcact ggtttgcgct gccaaccctc tatacgccgc gcttcgagtg gtttgccatt
     9601 ctgactattc tgccagcggc gttagtggtt attgccgaac acgtagggca cctggtagta
     9661 acggctaata tcgtcaaaaa agatctgctg cgcgatccag gtctgcaccg ttcgatgttt
     9721 gctaacggcc tgtcgaccgt gatctccggc ttctttggct ctacgccaaa taccacttac
     9781 ggagaaaaca ttggcgtgat ggcgatcacc cgtgtttaca gtacctgggt tatcggtggg
     9841 gcggcgattt tcgctatcct gctttcctgt gtcggtaaac tggctgccgc tatccagatg
     9901 atcccattgc cggtgatggg cggcgtttcg ctgctgcttt atggtgtcat cggtgcttcc
     9961 ggtattcgtg ttttgatcga atcgaaagtg gattacaaca aagcacagaa cctgatcctg
    10021 acttccgtga ttttgatcat cggcgtcagt ggcgcgaagg taaacatcgg cgcggcggag
    10081 ttaaaaggta tggcgctggc gaccatcgtc ggtatcggct taagtttgat cttcaaactg
    10141 attagtgtgc tgcgccctga agaagtggtg ctggacgcag aagacgcgga tataacagac
    10201 aaataatgta ccgaccgggc agtgttgctg cccggttcaa acatcatggg attctgtggt
    10261 aaacttctcg cgattttgtg aaatcctggt tgaggtatct ctgaacacac cggcacagct
    10321 ctctttgcca ctttatcttc ctgacgacga aacctttgca agtttctggc cgggggataa
    10381 ctcctcttta ctggctgcgc tgcaaaacgt gctgcgtcag gaacatagcg gttacatcta
    10441 tctctgggca cgcgaaggcg cggggcgcag ccatctgctg cacgcggctt gcgcggaatt
    10501 gtcgcagcgt ggcgatgcgg tgggctatgt cccgctggat aaacgcacct ggtttgttcc
    10561 ggaagtgctc gacggtatgg agcatttgtc gctggtctgt atcgacaaca ttgagtgtat
    10621 tgcaggcgat gagttgtggg agatggcgat tttcgatctc tacaatcgaa ttctggaatc
    10681 gggcaaaaca cgattgttga tcaccggcga tcgtccaccg cggcagttga atctgggatt
    10741 accggatctc gcgtcgcgac tcgactgggg gcagatctac aaattgcagc cactttctga
    10801 tgaagataag ttgcaggcgc tacagttacg cgcgcgtttg cgtggttttg aactgccgga
    10861 agatgtgggg cgtttcttgc tgaagcggct cgacagagaa atgcgcacgc tatttatgac
    10921 gttggatcag ttggatcgtg cgtcgattac cgcgcaacgt aagctgacca ttccgtttgt
    10981 gaaagaaatt ctgaagttgt agataaggtg tttattgtcg gatgcggcgc gaacgcctta
    11041 tccgaactac gcgaagttaa tccatagtat tcgtaggccg gataagacgt ggcaagcgtc
    11101 gcatccggca atgtgcttca actagcgatg gagcacatct taacccacga tttccagtac
    11161 ctgctccggt ggacgaccaa tccgcgcttt gccattcgcg accacaatcg ggcgctccat
    11221 tagcttcgga ttatccacca ttgcctgaat cagcgcctct tcgctaagcg aactgtcagc
    11281 caggttcagt tctttataaa gatcctcttt ctggcgcatc aattcacggg cgctattcat
    11341 ccccagcatt ttcagcaaat cgcgcagcgt tgccgcatcg gcgggtgtct caaggtagag
    11401 caccacttct ggctccacgc cgttttcttt cagcaggttc agcgtttccc ggctctttga
    11461 acagcgtggg ttatggtaga tttttacctg tttggtcatt gttcttcctt taatgcgaat
    11521 tacatcttgg tataaggctt aaagcgttcc tgcagctggc gcaactggtc gatgcgcgca
    11581 tcgtaacgcg cttgttgcag gctgcctaat ttcacctgcg aactggcgct actcaacagc
    11641 gaaatggcct gatcgagtcg tccggcgagc gcataacctt ctgctcgcgc agccagctcc
    11701 tgatcacggt tatttagcgc ggcttccgcc tgtgccagca aatcccagcc gttgctgtca
    11761 tctttattat taaaggtgta gcgattcaga atattggccg cttcttgtgg ttgaccgcct
    11821 tgcagataag cgttcgccag gttgagctgc aacaccggat tggtgcgtaa atcgcgggca
    11881 tttttcaggc gattgatcgc ttcattggct ttgttttgcc caagatcgat atcagtagcc
    11941 agatcgagat accatgcgtt gccaggttct gccgccagta acggttgcag cgttttacgc
    12001 gcctcgtcgt atttattggc ttccatcgcc tgtaaagcac gaccatattg cgctgctcgt
    12061 tgctgacgaa cgtttccttt cgcccattca tccagcaaat cactggtgag ctggttacgt
    12121 ccggaattat acatccccag tgtgcgcgct ttcgccagat agaaatcttc cgacgactgc
    12181 accaccatcg ggcgcatctg attagcacgg ttgcgggcat ctgccagacg actttccggc
    12241 aacgggtgag tcaataaaat ttccggcggg cgcgaggagt aacgcgcctg atcgagtaat
    12301 ttttcgagga aggttggcat cgcctgcgga tcgaatcccg agcgttgcag cacctgaata
    12361 ccaatgcggt ccgcttcctg ttcattttgc tgggtgaaac tgatcatccc ctgacgcgtt
    12421 cccgccagtg taccggtcag cgccgccatc cccgcctgcg gactggccat cgccagtaaa
    12481 atagaaccta acgcgccgac ccaggtcagc ggcgcgctgc gctgctgatc ttccatcgct
    12541 cgcgccaggt gacgttgggt gacgtgggag atttcgtgcg ccataactga agccagttga
    12601 ctttcgttat cggaataacg gaacagggca gagtgcagca ccacgttgcc gccaaagaaa
    12661 gcaaaggcgt taatttcgtc gttgttgatc agaaaaaaat gaaacggtgt cttaaccgaa
    12721 ttggcatgcg aaaccagacg catccccagc gaattaatat attgcgttaa cagcgggtca
    12781 ttaattaacg gcgcgctgcc gcgtagctgg cggacataat agtcgcccat ctgcatttcc
    12841 tgaccaatgg aaagcgtgct tcctgcggag gttcccatat ccggcaaggt gtctgcgctg
    12901 tcggcaaacg ccggggctac ctgaccaatg gtcattgcag caatgagggt tgcaaccagg
    12961 ttttttttca actgcctgaa cataacctct atcctgtatt tctgaagata gtcatttgac
    13021 cgatactgtg aaatatcgtt cccaccgcgc cgcctttgag tgtaacggcg aagattagcc
    13081 cactcaaatg acttttcagt ttcctgaatc cgtcataaaa agcgaagtct tttttgtgac
    13141 atttcgatac aattgcggat cgcaatcccg ctcttgaggt tcagggaagg tctttatgct
    13201 cgaaatgttg atgcaatggt atcgccgccg ttttagcgac ccggaagcga ttgccttgct
    13261 ggttatttta gttgccggat ttggcattat ctttttcttt agtggcctgc ttgctccgtt
    13321 gctggtggct attgtgctgg cctatttgct ggaatggcca accgtgcgcc tgcaatctat
    13381 tggctgctcc cgccgctggg cgacgtcgat tgtattggtg gttttcgtcg gtatattgct
    13441 actgatggcg ttcgtggtac tgcctatcgc ctggcaacag ggcatctact taatccgcga
    13501 tatgccgggg atgctcaata agctttctga ctttgccgcc acgttgccgc gccgctatcc
    13561 ggcgttaatg gatgcgggca ttattgatgc aatggccgaa aatatgcgca gtcggatgct
    13621 gactatgggc gattcggtgg tgaaaatttc cctcgcctcg ctggtcggtt tgctgaccat
    13681 agccgtctat ctggtgctgg tgccattgat ggtcttcttc ctgctgaaag acaaagagca
    13741 gatgctgaac gccgttcgcc gggtgctgcc gcgtaaccgt ggactggcag gacaggtgtg
    13801 gaaggagatg aatcaacaaa tcaccaacta tatccgcggc aaagtgctgg agatgatcgt
    13861 agtagggatc gccacctggc tggggttctt gctcttcggg ctgaactatt cgctgctgct
    13921 ggcggtgctg gtcggcttct cggttcttat tccgtacatt ggcgcatttg tggtgaccat
    13981 tccggtggtt ggcgtggcgc tattccagtt tggcgcaggt actgaattct ggagctgctt
    14041 cgcggtgtat ctgattattc aggcgctgga cggcaacctg ttagtaccgg tgttgttctc
    14101 cgaagcggtt aacctgcatc cgctggtgat tattttatca gtagtgatct tcggtggttt
    14161 gtggggattc tggggcgtat tcttcgccat tccattggcg acgctgatca aagccgtgat
    14221 ccacgcctgg cccgatgggc aaatcgcgca agaataatct tcagcccgac gaactgtttc
    14281 gccgggctga tttttcagga ttcctgacgt aaataaatag cccgataaca aatactcacc
    14341 agcactgcac cgccgataat attacccagc atcaccggga gcagattggc ggtaataaaa
    14401 tggctgaccg tcagtgccgg aaaattgtct gcgctactgt gcgccagttg ccgaaggggc
    14461 gtggggcaaa atggcgaatg gcaatggcga acggaatcac aaacaaattg gcgatacagt
    14521 gctcaaagcc actggcgaca aacagggtga tgggcaaaat catagcgacg attttgtcgc
    14581 ataatgaacg cccgcaataa ctcatccaca gcgccaggca aaccatcaga ttgcacataa
    14641 tgccgaggct gacagattca gtaaatgtat gatgcatttt gccctcggcg cagtgtaaaa
    14701 ccgcgactcc ccacatcgcg ttttcactca tcaccagccc ggaaaaccag attaacaaac
    14761 tgaaacaggc aatacctgcc agattaccgc aggccaccag aagtgcgtta atcagccaag
    14821 ttcgccaact aataacgccc cgactttttg ccatcaccgt cattaccgac gaggtgaaca
    14881 ggctggtgcc acaaaccgcc agcaaaataa agccgagtgt aaagcaaagg ccgcccacca
    14941 gatgggttaa tgcctgtgaa gacggggcat cggcgataac ggaaaggtaa aaagtaaatc
    15001 cgatcgccat aaacacgcca gcggacatcg ccattaaaaa gaccgacact ttactgcggg
    15061 caattttatg ggaggcaatc cgttcagcga ttgccgcttt tctggcgctc aactgcaagt
    15121 cgaaagagag tttgtttctc atgcatactc ctgcaaaagc agattacaac acctcgcgaa
    15181 ccgagatccc cagacgctgc attcgtgaca gcagcgtggt gcgcttcatc cctaatcgtg
    15241 tcgccgcgcc acggggcccg gcaacaatgc cattggtttc tcgcaatacc tgaacaatgc
    15301 gctgacgttc ttcttcgtca ttctctggcg tcgtcgggtg cagcaactgc gccattgaac
    15361 tgcgaagcgc tgaatcttca tttagcgtcg gcagtaaacg gctttgtcgg acatttagat
    15421 gtaaattcag attgttacca cgagtcaaca gtaccgcccg ctcaatcacg ttttccagct
    15481 cgcgcacgtt gcccggccaa tcccacgaca tcaactggcg tagcgcctcg gtcgggatgg
    15541 cgtcaattgc gcgattcata tggcgcgcca ttttttgcgt gaaatgcttt gctaaaagag
    15601 ggatatcttc cggacgatcg cgtagcggcg gcaattccag tgggaagaca ttcaggcgat
    15661 aaaagagatc gctgcgaaac tggcgatctt caaccatttg ccacaaatca cggttggtgg
    15721 cggcaatgac tctgacattc accgggatcg ttctactccc gccgagacgc tcaatctccc
    15781 gctcctgcaa tacgcgcagc aatttaggct gaagttctaa cggcagatcg ccaatttcat
    15841 cgagaaacaa cgtaccgcca tcggcaattt caaaacgacc acgatgggta ttaatcgcac
    15901 cagtaaacgc ccctttgtca tgaccgaata actcactttc cagaagactg gcggggatgg
    15961 cagcgcagtt gattttgacc agcggcttgt cgcgtcgcgg gctaagttga tggatcgctc
    16021 tggcgatcac ctctttgcca gttccggttt caccgcaaat caacaccgta ctgtcgctct
    16081 tcgccacaat atctacctgc tggagcaggt cttccattgc ctggctttga tagataatgt
    16141 caccgacgcc cagattcgaa aggagctgct cgctaagctg gtggttttct tgctgcaaac
    16201 tttcctgcaa atcggtcatg ctacgccagg catcggcatt gccaacggca atagcgatgc
    16261 gatcggctat gtgttgtagt agctggcagt tttcctcact aaagagagtg gaagaggtat
    16321 gcgccagtaa caatgcaccc ggtgtatggt tgccaaaggt aagcggtatc aggagcgcag
    16381 attcgcagcc gttagatgca agtaagagta ataacgggtc gcgttgccag agaaacagat
    16441 cgtctgcacg gtgcgtcaag gtcggttgtc gggtttgtag cgtttgtgtc agcaatacac
    16501 tgtcgccagg catattgcgt ggcagacacg cacaatgtga ggcagaaaga tcgctgcacc
    16561 acaggctgaa cttctcgttc tttcgatgat cgcccagtac catactgact gaagccagac
    16621 cgaaaaaatg atggatctca cgagcgacgt cagcgatcag atcgtcgaga tcaagatgtg
    16681 acagcactgc attagtgata tccaccagta cccgatgatg atcgcgatct ttctccagca
    16741 aacgcagcgc cacctgttgt tcttcatcat tgagccatga ttgcagaacc ggggtgataa
    16801 tgcgtgccag ccagttaaac agtgtgcaat cctggggagt aaaacggctg ccgtgggtac
    16861 gaataaagcg tagctccgcc attccactac tgccgagaag gacggcgtga cgcgaataat
    16921 cgaccatctc gccctgatac tctactgttg ccgtcacatc gctgccatca tcatggtagc
    16981 ggtaatagaa gttgcttttg agaacatgca gttcaataag ttgtaccggg ctgaacggcg
    17041 gcggcagcgg gatgaaggcg cgtaataaag acgccttgcc gtgtttctgt gctaaccgct
    17101 ccgcgagcat tccgtttacc gcttcaattg ttattccttg tggcggggca aacatcgcct
    17161 cgtctgacat agccatcaac agtccttatt aatgagaaat ccttctcacg caatttttct
    17221 ggccatcaga tagatggccg gttcctgcac aatttcatcc aacagatgaa tgaattgaat
    17281 gctacgcgcc tgccacacag acgtcgcgtc atctgccagt agcgcgaatg cccgggtcaa
    17341 cagggcggtg tggctggcgt caataacaat ctcaccaaag gtcatcaccc ccagcatctt
    17401 acgtcgggct tgctcctctt cgacctgtgc aagccaatct tcgtattccg tcagtgggca
    17461 gcggaaggcg acattcagac aatcaatcac gccaacgtga tgaccgatag ccagcgagta
    17521 atacattacc tgagagctgt gttccggcat ctcgtcgcta ctggcgacaa acttttttcg
    17581 cagcgtccag aaaacaattt ccccgcactc ctcagccatg taacccccgg agaacgcgaa
    17641 agagttgctg aacgatacta ttgagacgcg gatcgtcggc ttcgcgcaac caggtgttaa
    17701 cccgatttcc tgtaggatcg tcgcttaaat ggcgcaggag ccgatcgcaa atttctcgcc
    17761 cctgacgata gcccgccagc cgccgcgctt ctcgctcaat ggcgatacgc tgtgatggcg
    17821 ggatctgtgg ccacaacggt tgcatagtca ccccggtggg atcgcgataa tccacagcgt
    17881 gaatcttctg ttgcagcaaa ccgagcgcca cggcgaaacc gtgaatggtg gcggccggtg
    17941 ttggcgggca gccggggatc caaacatcaa tggggacaat ggtgtcgctg ccgccccaga
    18001 cgctgtagag atcgtggaaa ataccgccgc cgacaccgca cgcgccgtag gaaacacaga
    18061 ttttatgatc gggggcagac tcatacgccc gaagtgcagg catacgcatc gcccgggtga
    18121 ctgcgccagt aaataacaaa atatcggcgt gacgcggtga tgaaacaacc ttaatgccaa
    18181 aacgttctgc gtcgaatact ggtgtgatgg cagcaaaaat ttcgatttca caggcgttgc
    18241 agccgccgca atcgacgcga taaacgtaag ccgagcgacg gatatcctgt agcaaatgct
    18301 gcttcatctt ttgcgtttgc tcgtccagcg tgatgggctg gctgacatat tgcgtaagca
    18361 ctggactcat agctgctcct tagccaccag cggtacatct gtatcgtcgt tgatcagcgt
    18421 cgcgcgttgt ttgcactccg ggcagacgct cgcttgcgcc cgcaacattt cgcggttttg
    18481 tggcgcattt tgttgctgtg ccaacaattc agcagccagt gcgacggttt tttgcggggc
    18541 aaacgggcgt tcgcaacggc tgcaacgttg tagatggaac gtcgcgcggg tatagagatc
    18601 ggctttattg gtgacggtca gttcaaagtt attggtaagc tggatggctc tggtcgggca
    18661 cacttcttca caacgtccgc agtaaataca acgcctcaga tagagctgcc aggtgcgcga
    18721 attttgctgg tcgtcggtct ggatagtcag cgcatttgcc ggacaagcac aggcgccgca
    18781 ggcaatacat tggctgggca tcaggtccgg tttcccgcga aagcctgggc tgacctccag
    18841 tggcgcgaag ggatatttca ccgtcgcggt tccggcgcgc ataatagttt tcagtaactt
    18901 cagcatcttc tgtccttact tcagcggcga acggttacga tcaatgccgt agcgttcgat
    18961 ctctttatac ggcacggttt ttgactggcg cttgcgcaca tctaccagcg tcacacggtc
    19021 ggtacaggag tagcagggat caaggctacc gataatcagc ggtgcgtcag aaacggtatt
    19081 gccgcgcagc atgtaacgca acaccggcca gttggcgtag gtggcggcac gacagcgcca
    19141 gcggaacaat ttttggttat caccgagcat gctccagtgc acgtcttcac cgcgtggcgc
    19201 ttcaacaaag cccagcgcga atgcgtgagg tttatagcta aagccttcgg tcagcagcgg
    19261 ggtatccggc atgttgtcga gggcaaattc cagcattgcc agcgaatcaa acgtctcttt
    19321 gacacggacc atcacgcggg agaaaacatc gccgccggtg aaggtaaaca gtgtttttgg
    19381 aatattgccg tagtcggcgt aggggtgatc aaagcgcaaa tcacgggcaa aaccactgcc
    19441 gcggatcagc ggccctacag ggctataatc acgggcgatt tgtcggtcga gaatgccaat
    19501 gccctgagtg cgttgttcca tattcggcat agcaagcagc atctctacca gctccgacac
    19561 gtcggcgcgc atctcgcgca ccagtttcag cgtttgcaga cgttgctctt tgagaatatc
    19621 gcggcgaaca ccaccaatca gattcagacc gtaggtttta cgcgacccgg tcagcaattc
    19681 cgccatcgtc atcgactttt cccgcacgcg gaaaaattgc ataaagccgg tatcaaaacc
    19741 aacaaaatgg caggagaggc caaggttgag caaatgactg tgtagccgtt cgacttccag
    19801 cagaatcgag cgaatggtat gcgctcgttg cggcacctca atccccagtg cattttcaac
    19861 cgagttggta taggccacac tgtgggcaaa accgcaaatc ccacacacgc ggtccgataa
    19921 gaaggtcact tcgttgtagc ccatccgcgt ttctgccagt ttctccatgc cgcgatggac
    19981 ataaaacagg cggtaatcag catcgacaat ttgctcgcca tccacaaaca agcggaagtg
    20041 acccggttca tcggaggtga tatgcagcgg gccgacaggg atcacccgcg catcgctgtt
    20101 gccctcattg ataaacgcat acgtttcgga atctgtcgtc ggttcagggc gcagtcgata
    20161 atccatcgca tctttgcgca gcggatgcat atcttccggc cagtcatcgg gcaacaccag
    20221 gcgacgctga tccggcaggc caaccggaat cagcccgtac atatcgcgaa tttctcgctc
    20281 gccccagacc gcggcaggga cgcgcggtgt gactgacgga aactcccgac tgtcggcatc
    20341 gaccagtgcc ttcaccacga tccagcattt ttcggcccct tccattgaaa gggcataata
    20401 aaccgcgtaa tgaccgttaa gtgtccgctc gtcgttgcca aacaggactg gaagccagcc
    20461 atcatgttga taataaagat aatgtacaac gtcaggcagc agattgattt tcaccgtaat
    20521 ggtgacctgt tcaggcgttt gtcgctcttc atccagcacc gcgccgggga actgcgtttt
    20581 cagggcggcg agaatcgctt cgccacgatt tgacgatgaa ttaacgttca ctgtgtttct
    20641 ccgaaacaga tgcggtgcct gaaggcaaaa aatcatgcca ggtgctacgt tgtgcaggca
    20701 ggtcgtgcgt ccctgagagg actatagtgg aagcgcccgc caggatcctg atgacaggtt
    20761 gtggaatatg cgttcccatc gccagcatca tgaccagcag aatcaccatt ggcgaggtgg
    20821 tcaaccagcc gagatcaccc cggttaacgg cctgcggcgg tttcgccatt aacacccgcg
    20881 cagccatccg taccaggccc gccagcacca gcgttaacag caataacagc aggacgataa
    20941 tcagcaggtg attacgtgcc agtcctgcgg taacggtcat aaattcgcta agaaaaatgt
    21001 tgaagggcgg catccctgcc agcgccagcg caccgccgcc aaacagcacg gcggtaaatg
    21061 gcatgatttt gagcatccca cagacgacgt tgagatcgcg cgtgccgtac ttgagcagta
    21121 cattgccgga accgcagaac agcagcgttt ttgccagact gtggtttaag gtgtgcagca
    21181 gcgcggcaaa aattcccagc ggcccgccaa tgcctagcgc caccgcgacc agccccatgt
    21241 tctccacgct ggagtacgcc agcagacgct taatgtcccg ctgtaccaga atgaaaaatg
    21301 ccgccacggc aaccgacaac atgccgaaga tgagcaacaa ccggttgggg aaatcgctgc
    21361 cgatggcctg gcagataatg atgtaatagc gaattagcac caacagcgcg cagttcagca
    21421 atacggcgga gagcagggcg ctgaccggac tcggtgcttc actgtgagca tccggcagcc
    21481 aggcgtgcat gggaaatagc ccggttttgg tgccaaagcc aattagcaca aacacaaagg
    21541 ccaacagcat taatgttgga tcaagcaagg acgattgctt aagaacctcg ctccagaata
    21601 tcgccatttc tgcctgcggc ataacgctgg cggcgttggc gtataccagc acggtaccga
    21661 acagaccaaa agcgacacca acagtacaaa taatgatgta cttccatgct gcttccagcg
    21721 atgaacgctg accgtaaatg cctaccagaa acgccgagct taaggtggtg gcttcgatcg
    21781 ccgcccacat cacaatcagg ttattgctgg taacaaccag cagcatggtg aacaaaaaca
    21841 gatggaagaa accgtagtaa tcgcacagtg taacgggtga aagctcgccg tgtgccactt
    21901 catgacgcat gtagccaatc gagtaaacac cggtgagaaa gccaatcaca ccaagaatgg
    21961 cgaggaacaa accgcccaga ccatcaatat gaagccacag tcccgcagcg aatatttctc
    22021 ctgcatcagc ggcagtttgg accacccaga gtgccagaat cagcagcagt gtgatcccta
    22081 agctatgtaa tacagtcacc gtacaagtcg cagagagccc ccgtttccgg caggcaaaac
    22141 agagcagcga aaaaagcagc ggcgtgagca ggagtaaagc gaacatcaca gaataactca
    22201 tctcattatc ccttcagcgc ggtcaagttg ttcacgtcca gcgtgccgtg ggtacgccat
    22261 atttttcgtg ccagtaacac catcacaatg acggcgaaga tggcgtcggt agcgatacct
    22321 atttccacca gttccggtgc tcgccaggca agaagcgcca gcaccagatg ggagccgttt
    22381 tccatcaggc agtaaccaaa aatttgccgc aggatattgc gctggctgac aatgcacagc
    22441 aggccaagca gaaaatgacc taacgctacc gccagcgccg gtttcagccc ggtagccatc
    22501 ggtagcttca cgggctgaac gacaaatgcg caaagcagga caattaacgc cgcgagcagt
    22561 gccatcattg ccggaccgaa taacgctttt tccgggatgt tctggggaat atttcgtgca
    22621 gcgtaagtca tgattaacgg taccagcagc actttggtga taaaggcact ggcggaccag
    22681 atcagcagtt gctctgcggc gaacaggcac gagagagtgg cgaaaataga caccagcacc
    22741 agcgactggc aggcgtaaaa tccgcatgac aggcgatagc ttttgacgct aatcacaaac
    22801 agcgatgtca gcatcatcag tcccgccaga ttatttacga tcatagaacc ggtcattcat
    22861 catctcctta ctgcaaccag gtcgcggcga ttacgctgga aatcagcgac atcacaatca
    22921 gtacaatcaa caccaggcgc attgaccctg gcagcggtgc ggcatcggcg acggcctcgc
    22981 tcggtttgcc aggcacaacg cgaccaaacc agcgaataaa ccaggcgaaa ctggcgaccg
    23041 attcaatcat cagcagaatc atggcgggca gcaggatcca gtactccact gacaacgcaa
    23101 aacaggcggc aaacagcggg aatttactga agaagccgtt gaacggcggc acaccggtaa
    23161 tcgccagcgc tgccacgcag aaacccacgc ctggcaacgg cagggtgtgc aatacgccac
    23221 gcagacgcgg caacaagcgc gtgccgcagc tgtaactcag cgcacctgct acaaggaaaa
    23281 acaggctttt agcgaacgcg tggttgacga tgtaggcgat gctgccctcc agtgccagcc
    23341 gcccactttc accatcgatg cggcgtggag ataggcgctg atcggtgttg gcgcttccat
    23401 tgcgtccggt agccacgctt gcatcggtag ctgggccgat ttcccccacg cggcaaacag
    23461 gatgccgcca taaaccagat aacgtgcgtc gccatgtaac tcgctcatcg cgctaagcac
    23521 aaacgttccg gtctgcaaaa acagcgtggc ggcggcaaga tacaacccca acgaaccgat
    23581 atgggtgata agcaacgctt ttagtgctga acgctgcgct ttatcgctct ggtaataact
    23641 gatcaacgcc caggagcagc cgccctaatt tcaaaaaaca acaactgacc gagcagcgtc
    23701 gaggagagta ccagtcccgc catcgcgccg ataaacacca gcaaaaatgc gtaataacga
    23761 ttcgtgccgt tatgcgggtg ttcgcgattt ttatccgtca gataacccgt ggagtagatc
    23821 gtgaccagca aaccgagaaa caccaccaca aacagaatca gcgtactcac gcgatcaatg
    23881 accaggccaa acaatgccac atcccccacg ttgaccaacg tcaacgtgac ggcaacttta
    23941 tcggcctgat aaaacgcgga gatcagcgac aacatgcaca gcgtggtcag tgcggcgaat
    24001 aaaaccccca ttcggcggcc cgacgttgtg gcgaaaacga aacgaccagt gcgccgataa
    24061 aaggcagcat taacgtcgtc agagcaagat tttccatatt ccgtcagtgc tccttacaga
    24121 ccggttaacc agaagaccca tgcaagcgca gcaaggctga agccaagcca ggtcacatgg
    24181 tgaatgagta aaaaacgccc gcgtgccagc gtgttttctg cgattgaggc cagtacaaaa
    24241 atcagcaaaa ccttgagcag cgtaacgaca agtgaagtca gcaggcaggc gagagaaagt
    24301 tcttgcgcgc gcccaaagag cagaaacagg gccacaaaca gtgctgccat cacgacctgt
    24361 ttcagcccca gcccccattt cgctagcgcc agcccggcac cggaatattc ggtcagcggg
    24421 ccttcctgta attcctgttc tgcttcagca acatcaaagg gaatttttcc catctcaatg
    24481 aagcaggcaa aaccacaggc cagtaacgcc agtacggtgg ttagcggcga gttccagccc
    24541 gttgccagcg tattgctgat catctcgata tgcgtggaac ctgctatcag cgccaatacc
    24601 agcagtgaga gaatgagcat gggttcgacc agaatgccga gcgtcaactc gcgactggca
    24661 ccgactcccg caaacgggct tccggtatcc agcccggaaa gagcaaagaa aaaacgaaac
    24721 agggcaagaa gatagataag ggtgatcaga tcgccgccgc ccgcaaaagg ggaaacggta
    24781 ataaaaagtg gtagggccat cgccagcacc agcatgctgc tgattaatac ccacggcatc
    24841 aggcggaaca tcagacctga agatataggc gcaacttcct ggcgtttaaa cagtttgtgg
    24901 atatcgcgat aatcctgcca gatccccggc ccgcggcggg agtgcatacg cgcgcgtatc
    24961 tgccgggaaa tacccgtaaa aagcggggtt agcagcagaa tcacggcctg tgctaacgca
    25021 aaaatgacca gatatccgtc gcaaagagtt tgtctcatgg tgatttcctt agacggcaat
    25081 agcgattagc agcacaacca gtgcggcgac cacatacagg caatagagac gaaagtcgcc
    25141 gctttgcaga tgctgtattt ctttggccag ccgttgggtg gcgctcacga tggggcggat
    25201 cacccgctca tcccagaagg gttctgtgct ctgagccctg gcggtgacgt gcgcaagacc
    25261 tttatttagc ctcagcgtag ggtcgaactg ttgtcgtaga cgaaatagcg cagaaaagac
    25321 cacacgcagc ggctgcatca cgccattgcc tgacggggcc atcgcatttt cccagccgta
    25381 gccgcatgcc caggcatctc ctgtgcgacg aaacgctgcg cggcgcgaac gacaccacag
    25441 ccagtaaagg ccaggcagca aaggcatcgc cagtagtaac agcaacagta atgagggggt
    25501 gacccgtgta tgaaacgtgc cgggtacaag tgctattccg ctggcgacag tgacgggagg
    25561 ggtattggta aacgcatggg caatatgcat tatcttcggt gccagccaac tggcactaag
    25621 cgcaattaat acgcagagtg ccgcgagcag tagcatggcg acgatcatcg tatttggcac
    25681 ttcctgtgcc tcttcagcgt gtgtactgcg cggcgcacca cagaaagtaa taccgtacat
    25741 tttgacgaag cacattactg ccagcccacc agtgactgcc agcattacca tagcaatagg
    25801 acccgcaagt tgtagcgcta cggcttccac acgacttagt gagaacagcg actgccaggt
    25861 gtaccattcg ctgataaaac cattcagcgg aggaatggct gatatcgcga ggcaaccaat
    25921 caggcatgct gcggctgtcc acggcatccg tttcgccagt gcccccattt tttccatgtc
    25981 gtgggtatgc aaacgcgaaa taatcgcacc cgcgccgaga aatagcagcc ctttgaacag
    26041 cgcatggttg agcagatgaa acagtgcgcc gagcagtcca accacggtga gcagcgggtc
    26101 gtgcagtgac agaccgtcca tcgccacacc gaccgccagc aaaataatgc cgacgttttc
    26161 gacggtactc caggccagca gccgtttgat atcctgttcc gccagtgcat acagcacgcc
    26221 caggagcgcg gagattgcgc cgatcgccat caccagagtg ccccaccaca gaggcaaacc
    26281 cgtttgcgcc agcagatcca tcgctacttt caggatgccg aaaataccga ttttgaccat
    26341 tacgccagac atcaacgccg aagcgtgcga tggtgcggca gggtgagcgc gcggcaacca
    26401 gctgtgcaac ggcatcatcc cggctttcgc gccaaaaccg aaaaaggcca gcagaaacac
    26461 cgccgacgcc agccccggag aaagtgaaag cgtgcgaaac tggcaaaatc gaggctgccg
    26521 ctttcgcgcc ccatcagcaa gaaggcgatc ataatcagca ccgatccggc gtgggcgata
    26581 aaaaagtaga gcatgccagc gttgatcgac gttttatcct gcctggcaat gaccagaaac
    26641 caggaagaca gcgacatcat ttcaaacagc acgatgaacc aaaaagcgtt gtccatcacc
    26701 agcagggcaa ccatcgatgc gatgaaaaga ttcataaaga agcccatcgc cgccgcgcct
    26761 ttgccctcgt attcgcgcat ataagtcaat gaatagagcg aacaaaccac caccagcaag
    26821 gagataacca gcaccataaa tgccgagagg ctatccattc gcagggttaa atcggcaaag
    26881 tcaaaagggg tggcaaaatg ggcgactaaa gttacaccag catgtaattg cgtaattccg
    26941 ctgatgatgc caatcacgcc gcccaccagc gatgtgatgc cggaaagctt aatagccagt
    27001 ctgtccagac cgagtaaaaa cagcgaagcc agactggcaa acagatagag gatcagcgac
    27061 caggttaata attgcagggc atccattagt gttgctcctg agtgagggaa aggggatcct
    27121 ccccgccatt ggcaaaccag cttgcggcaa ggcgctgttt ttctttcatc tgacgttgca
    27181 ggctatcgtc ggtgattagc cgtaacgcct gattcgggca agcgcgaacg caggccggac
    27241 cttctggcaa gaaatcacac aggtcgcatt tcaccgcgac ggtctggaca cccggttccc
    27301 agcgcagcaa cgcatgttgg ggcagcacgt tttcttcgcc gtctttgagt gagccttcag
    27361 cctgaaaaac atattgcgca tgggcattca ccggacggct tcctgaagcg ctgattgcgc
    27421 caaatgggca gaccacggcg caaagcttgc agccaataca gaggctttcg ttgagttgga
    27481 tcgcatcatc cctctgagag atggcattga ccgggcagac ctgcaggcaa ggggcttcct
    27541 cacagtgatg acacacgaca ggggcagtga ttgttgacgt cttcgccagg gccaggcgcg
    27601 ggtgttgctg taaaccttgc gttttatgca cgtccgaaca ggcagcgaga caggtattac
    27661 atcctgtaca ccacagtggt tcggccacca caaagcggtt catgtcggct ccttgaaaat
    27721 gatatgaaac attgcatttc atattgcata aaggatgcca ttctgattaa ctcaatatat
    27781 tcaataagtt atgtattgat tggattctga acggtacaaa aatgatggtc attaacgttc
    27841 agcaaaaaat ggattcgaca cccgtgtcgc aggggaaagc gagaatgtga tcttgatcac
    27901 gagaagtgag gtatgctggc cgcaagcgca gccagcacgg aatggagcaa agtaatcagg
    27961 cgtgttcttt cagccagttc agcacaacgt cgtggtgatt gctggttttg aaatcgtcaa
    28021 agacatgttc gattttgcca tcagcgtcaa tcaggaagct gatgcgatga atgccatcgt
    28081 aggttttgcc catgaaggac ttttcacccc agacgccgaa ttgttcgcac acctggtggt
    28141 cctcatcaga caggagcgta aagttaagca gctctttttc cgcaaaacgg gagagttttt
    28201 cgggtttatc ggtgctgata cccagcacat caacgcccgc ttttttcaac tcatccatgt
    28261 tatcgcgtaa gccgcaggcc tgtacggtac agccgggggt catggctttc gggtagaaat
    28321 aaaccagaac acgctgtccc tggaagtcgg tcaaattaac ttgttctccg tcttgatccg
    28381 gcaagctaaa tttcggtgcg atatcaccgg ctttcagtgg attcattact taactccatc
    28441 ctgttcatca tgttgggaat aattgacgac gttaatactg ccttgtgcat tgagttctgt
    28501 acatagggct ttgaacgctt gctcaatatt tgctgcgtcc gcagatgcgg ggctgtgggc
    28561 ggttatctga atatgcaact gcgcagcccg ttcattttca gcaggttgtg tgcgcgacac
    28621 cagctccgca atgttcatat gatgcgcgtc gaaaagtgct gtgaagcgtt caattaaatg
    28681 cggggagtct gccacatcga cctgaaccca gacagatgct ggcattggcg gacgcggacg
    28741 cgccgtcgtg cgcttcatca cgattaaaag atccagttcg gcacctttca acggtaacgt
    28801 tgattcaatc agagtaatgg cattccatga accggaaagc agcataataa acgtgaactc
    28861 ttctcccagc atcgccaggc gactgtcttc aatattacag ccgcaactac tgacatgacg
    28921 ggtgatggtg ttcacaattc cagggcgatc ggcacccaac gcagtgatca ccagataatg
    28981 ttgcgatgac agtgtcaaac tggttattcc tttaaggggt gagttgttct taaggaaagc
    29041 ataaaaaaaa catgcataca acaatcagaa cggttctgtc tgcttgcttt taatgccata
    29101 ccaaacgtac cattgagaca cttgtttgca cagaggatgg cccatgttca cgggaagtat
    29161 tgtcgcgatt gttactccga tggatgaaaa aggtaatgtc tgtcgggcta gcttgaaaaa
    29221 actgattgat tatcatgtcg ccagcggtac ttcggcgatc gtttctgttg gcaccactgg
    29281 cgagtccgct accttaaatc atgacgaaca tgctgatgtg gtgatgatga cgctggagct
    29341 ggctgatggg cgcattccgg taattgccgg gaccggcgct aacgctactg cggaagccat
    29401 tagcctgacg cagcgcttca atgacagtgg tatcgtcggc tgcctgacgg taacccctta
    29461 ctacaatcgt ccgtcgcaag aaggtttgta tcagcatttc aaagccatcg ctgagcatac
    29521 tgacctgccg caaattctgt ataatgtgcc gtcccgtact ggctgcgatc tgctcccgga
    29581 aacggtgggc cgtctggcga aagtaaaaaa tattatcgga atcaaagagg caacagggaa
    29641 cttaacgcgt gtaaaccaga tcaaagagct ggtttcagat gattttgttc tgctgagcgg
    29701 cgatgatgcg agcgcgctgg acttcatgca attgggcggt catggggtta tttccgttac
    29761 ggctaacgtc gcagcgcgtg atatggccca gatgtgcaaa ctggcagcag aagggcattt
    29821 tgccgaggca cgcgttatta atcagcgtct gatgccatta cacaacaaac tatttgtcga
    29881 acccaatcca atcccggtga aatgggcatg taaggaactg ggtcttgtgg cgaccgatac
    29941 gctgcgcctg ccaatgacac caatcaccga cagtggtcgt gagacggtca gagcggcgct
    30001 taagcatgcc ggtttgctgt aaagtttagg gagatttgat ggcttactct gttcaaaagt
    30061 cgcgcctggc aaaggttgcg ggtgtttcgc ttgttttatt actcgctgcc tgtagttctg
    30121 actcacgcta taagcgtcag gtcagtggtg atgaagccta cctggaagcg gcaccgcttg
    30181 cggagcttca tgccccggct ggaatgattt tgccggtgac ctccggtgat tatgcaatcc
    30241 cggtgaccaa cggtagtggt gctgtcggta aggcgctgga cattcgtcca ccagcccagc
    30301 cgctggcact ggtttctggc gcgcgtaccc agttcacggg cgataccgct tcattgctgg
    30361 tggaaaatgg tcgtggcaat actctgtggc cgcaggtggt tagcgtgctg caggcgaaaa
    30421 actacaccat cacccaacgt gatgatgctg gtcagacact gaccaccgat tgggtacaat
    30481 ggaaccgtct ggacgaagac gagcagtatc gtggtcgtta tcaaatctct gttaagccgc
    30541 agggttatca gcaggcggtt acggttaaac tgctgaacct ggaacaggcg ggcaaaccgg
    30601 ttgcagacgc ggcttccatg cagcgttaca gcacggagat gatgaacgtt atttccgccg
    30661 gtctggataa atctgccact gacgccgcga acgctgcgca aaatcgtgcc tccaccacta
    30721 tggacgtaca aagtgcagct gatgacaccg gtttaccaat gctggtcgta cgcgggccgt
    30781 tcaatgtggt ttggcaacgt ctgccagcgg cgctggaaaa agtgggcatg aaagtgaccg
    30841 acagcacccg ttcgcagggc aacatggccg taacttataa gccgctgtct gacagcgact
    30901 ggcaggaact gggcgcgagc gatccaggcc tggcatccgg tgactataaa ctgcaggttg
    30961 gcgatttaga taaccgcagc agcctacagt tcatcgatcc gaaaggtcat actctgactc
    31021 agagtcagaa cgacgcgctg gtagctgtct tccaggctgc gtttagcaag taaaaataca
    31081 gggctggagt catccggccc ttttttctga tatgatacgc aaacgtgtgc gtcggcagga
    31141 aaacgcgatt ttagcggtaa ttcgcacgaa atttgtttgt cggacgtagt tcggataagg
    31201 cgttcacgcc gcatccgaca aaacatccgg cacaccagac agcaaaagat tttaaaacgt
    31261 taattcacac ccaggagtga taaagatgca aaagcaagct gagttgtatc gtggtaaagc
    31321 gaaaaccgta tacagcacgg aaaacccgga cctgttggtg ctcgaattcc gcaatgatac
    31381 gtcagcaggg gatggcgcgc gcattgagca gtttgatcgc aaaggtatgg tgaacaacaa
    31441 gttcaactac ttcattatga gcaaactggc tgaagcgggt atcccgactc aaatggagcg
    31501 tctgctctcc gataccgaat gtctggtgaa aaagctggat atggtgccgg ttgagtgtgt
    31561 cgtgcgtaac cgtgctgctg gctctctggt gaaacgtctt ggaatcgaag aaggtattga
    31621 gctgaacccg ccgctgttcg atctgttcct gaaaaacgat gccatgcacg atccgatggt
    31681 caacgaatct tactgcgaaa cctttggctg ggtgagcaaa gagaacctgg cgcgtatgaa
    31741 agagctgacc tacaaagcga acgacgtgct gaaaaaactg ttcgatgatg ctggtctgat
    31801 tctggtcgac ttcaagctgg agtttggtct gtacaaaggt gaagtggtac tgggcgatga
    31861 gttctccccg gacggcagcc gcctgtggga caaagaaacg ctggagaaaa tggacaaaga
    31921 ccgtttccgc cagagcctcg gtggcctgat cgaggcctat gaagccgtcg cccgccgcct
    31981 gggtgtacag ctggactgat ttttctggtt gcttgtttat ttagccggag ggtactccgg
    32041 ctaaatgtct tcgatacccc cgctacaata cttcgcatta tctccctttg acaggaaagt
    32101 aataacaggc caatatgtat atacatgacg tatatcccaa aaaaaggggg ggctatggaa
    32161 actactgtat ttttaagtaa tcgcagtcag gccgtcagat taccgaaagc ggtcgctctg
    32221 ccagaggacg ttaagaaagt agaaattatt gcgattggtc gtacaagaat catcactccc
    32281 gccggtgagt cctgggacag ttggtttgat ggcgaaaatg tgagtgcgga ttttatggat
    32341 atccgtgatc aacccgcaat gcaggaaagg gaatcattct gatgctgaaa ttcatgctgg
    32401 ataccaacat ctgtattttc actattaaga ataaaccagt acatgtcaga gagcggttta
    32461 acctgaattc tggccggatg tgtataagtt ctgtaacatt gatggagctt atctatgggg
    32521 cagaaaaaag tcagatgcca gaacgcaatt tggcggtgat tgaaggtttc gtatctcgtt
    32581 tggaagtgct tgattatgat agtgctgctg cgacgcatac tgggcaaatc agggccgagc
    32641 ttgcccggca gggaaggcct gttggacctt ttgaccagat gatagcggga catgctcgca
    32701 gtcgcggttt gattgtggta accaacaata cccgagagtt tgagcgagtg gcgggaatca
    32761 gactagaaga ctggagctaa cattctcttt tacttctaac attcgtaaat tatataacgt
    32821 ggcatgaagc cttaattcct ccgccatttc atcccgcttt cctgtggtaa tcttcctctg
    32881 aaccacctac gatcatttct ataatgaata tattgttgag gtatctatgc gttggcaagg
    32941 gcgacgtgaa agtgacaatg ttgaagacag gcgcaacagc tccggtggtc cgtctatggg
    33001 cggtcctggt tttcgcctgc caagcggtaa aggcgggctg attttactgt tagtcgtgct
    33061 ggttgcaggc tactatggtg ttgatttaac cgggttaatg actggacagc cggtttccca
    33121 acaacaatca acgcggtcca ttagccctaa tgaagacgaa gctgcaaaat tcacctcggt
    33181 gattctggca accacggaag acacctgggg acaacagttc gagaagatgg gtaagaccta
    33241 tcagcaaccg aagctggtca tgtaccgtgg aatgacgcgc accggctgcg gggctggtca
    33301 gtccattatg gggccgttct attgcccggc ggatggcaca gtttatatcg atctctcctt
    33361 ctatgatgac atgaaagaca aacttggcgc ggatggcgat tttgcccagg ggtacgttat
    33421 cgcccatgaa gtcggtcatc atgtgcagaa actgttaggc atcgagccga aagttcgtca
    33481 actgcaacaa aacgcgacgc aggcggaagt gaaccgctta tctgtgcgta tggaactcca
    33541 ggccgactgt tttgccggtg tctgggggca taacatgcag cagcaaggcg ttctggaaac
    33601 cggcgatctg gaagaggcgc tgaacgcggc gcaggccatc ggcgatgacc gtttacaaca
    33661 gcaaagtcag gggcgagtag taccagatag tttcacacat ggcacttctc agcaacgcta
    33721 cagctggttt aaacgtggtt tcgacagcgg cgatccggca caatgcaata cttttggtaa
    33781 aagcatttaa cttccggggc agggatggct gaactgactg cgcttcacac attaacagcg
    33841 caaatgaaac gtgaagggat ccgccgcttg ctggtgttga gcggggaaga gggttggtgt
    33901 tttgatcatg cgcttaagtt gcgtgatgcc ttacctggcg actggctgtg gatttcgccg
    33961 cagccagatg ctgaaaacca ctgttcaccc tcggcgctac aaactttact tgggcgcgag
    34021 ttccggcatg cggtattcga cgcccgccac ggctttgatg ccgctgcctt tgcagcactt
    34081 agcggaacgt tgaaagcggg aagctggctg gttttgttac tccctgtatg ggaagagtgg
    34141 gaaaaccaac ctgatgccga ttcgctgcgc tggagtgatt gccctgaccc tattgcgacg
    34201 ccgcattttg tccagcatct caaacgcgta cttacggcgg ataacgacgc tatcctctgg
    34261 cggcaaaacc agccgttctc gttggcgcat tttactcccc gtactgactg gcaccccgcg
    34321 accggcgcac cacaaccaga acaacagcaa ctcttacagc agctactgac catgcctccg
    34381 ggcgtggcag cggtaacggc tgcgcgtggg cgcggtaagt cggcgttggc agggcaactc
    34441 atttctcgta ttgcgggcag tgcgattgtc accgcgcccg caaaagcggc aacggatgta
    34501 ctggcacaat ttgcgggcga gaagtttcgc tttattgcac cggatgcctt gttagccagc
    34561 gatgagcaag ccgactggct ggtggtcgac gaagccgcag ccatacctgc gccgttgttg
    34621 catcaactgg tatcgcgttt tcctcgaacg ttgttaacca ctacggtgca gggctacgaa
    34681 ggcaccggac gtggtttttt gctgaaattt tgcgctcgct ttccgcattt acaccgtttt
    34741 gaactgcaac agccgatccg ctgggcacag ggatgcccgc tggaaaaaat ggttagtgag
    34801 gcactggttt ttgacgatga aaacttcacc catacaccac aaggcaatat cgtcatttcc
    34861 gcatttgaac aaacgttatg gcgaagcgag ccagaaacgc cgttaaaggt ttatcagtta
    34921 ttgtctggtg cgcactaccg gacttcgccg ctggatttac gccggatgat ggatgcacca
    34981 gggcaacatt ttttacaggc ggctggcgaa aacgagattg ccggagcgct gtggctggtg
    35041 gatgaggggg gattatctca acaactcagt caggcggtat gggcaggttt tcgtcgcccg
    35101 cggggtaatc tggtggccca gtcgctggcg gcgcacggta gcaatccact ggcagcgaca
    35161 ttgcgtggac ggcgggtcag ccggatagca gttcatccgg cgcgtcagcg ggaaggcaca
    35221 gggcagcaac ttattgctgg tgctttgcaa tatacgcgtg acctcgacta tctttcggtg
    35281 agttttggtt acaccgggga gttatggcgt ttctggcacc gctgcggttt tgtgctggtg
    35341 cggatgggta atcatcgtga agccagcagc ggttgctata cggcgatggc actgttaccg
    35401 atgagtaatg cgggtaaaca actggctgaa cgtgagcatt accgtttacg tcgcgatgcg
    35461 caagctctcg caaagtggaa tggcgaaacg cttcctgttg atccactaaa cgatgccgtc
    35521 ctttctgacg acgactggct tgaactggcc ggttttgctt tcgctcatcg tccgctatta
    35581 acatcgttag gttgcttatt gcgtctgcta caaaccagtg aactggcatt accggcgctg
    35641 cgtgggcgtt tacagaaaaa cgtcagcgac gcgcagttat gtaccacact taaactttca
    35701 ggccgcaaga tgttactggt ccgtcagcgg gaagaggccg cgcaggcgct gttcgcactt
    35761 aatgatgttc gcactgagcg tctgcgcgat cgcataacgc aatggcaatt ttttcactga
    35821 ctccttcaat tttctcccat ggtcattgtg agtcagcggc gtaaaattaa tgacatcagt
    35881 taaggagttc gccatgaaac atgaccattt tgttgttcaa agcccggata aacctgcgca
    35941 acagttgtta ctgcttttcc acggtgtcgg ggataacccg gtggcaatgg gggaaatagg
    36001 tagctggttt gcaccgctgt ttcctgatgc gctggtggtg agtgtcggtg gcgcggagcc
    36061 gagcggtaat ccggcggggc gtcagtggtt ttcagtgcag ggtattacgg aagataatcg
    36121 ccaggcgcgt gtggatgcca tcatgccgac gtttattgaa acggtacgct actggcagaa
    36181 acagagcgga gtaggggcta acgccacggc gctaattggt ttctcacaag gcgcgattat
    36241 ggcgctggag agcattaaag ccgaaccggg ccttgcttcg cgcgtcattg cctttaacgg
    36301 acgctatgcg agcctgccgg agaccgcgtc tacagccacg acaattcact tgattcatgg
    36361 tggtgaagat ccggttatcg atctggcgca tgcagttgcg gcgcaggaag cgttaatcag
    36421 tgccggtggt gacgtgacgc tggatatcgt ggaggattta ggccatgcga tcgacaatcg
    36481 cagtatgcaa tttgccctgg atcacttgcg ttataccatt ccgaaacatt atttcgacga
    36541 agcgctaagt ggcggtaagc ctggcgatga tgatgtgatt gaaatgatgt aaaagacaga
    36601 ttacctggcc tgataagacg cgtgagcgtc gcatcaggca tcgttcacca ttgccggatg
    36661 cggcgttaac gccttatccg gcctacggtt gagcactcag cttacttctt cggttgatcc
    36721 tttttcggcc agtcgtcgtc atcgtcccac ttatcgttga aatcacgatg cgggggaagc
    36781 tccggcttgt tggcgagaaa tttcttatgg tcgacgcgct tgagatcttt aatcacgttc
    36841 agcaggacgc ctaccaaaaa gacaatcacc agaatccacc aatatttagc cagccagtcc
    36901 atgcttattt cctcttgcag aaccactcat cacgcgacga gctgttccat gatacgttga
    36961 tacatacggg caagtagctg caggtcggca gcgttcacac attcattaat tttatgaata
    37021 gtggcattga ccggcccgag ttccaccacc tgcgccccca tgcgggcaat aaagcgcccg
    37081 tcggacgttc cgcctgtggt cagtagctgc ggtttaattt cattatagtg ctcaaccgcg
    37141 ttaacgaccg catccaccag tttaccgcgc gcggtcaaaa atggctgccc ggaaagccac
    37201 cagtccaccg tataacgcag ttgatgtttt tcaagcaggg caagcacctg cgctttgatc
    37261 atctcatcag tcagttcggt gctgaagcgg aagttaaact gcacaaacag ttcacccgga
    37321 ataacgttgt tactgcccgt tcccgcctga atattagcaa tctgcatact ggtcgccggg
    37381 aaaaattcat tgccctgatc ccactcaata gccactaatt cattaaggaa aggtgctgcg
    37441 cgatgtactg gattgtcagc cagatgcggg taggccacat gcccctgaac gccatgaatg
    37501 gtaaggttgc aggttaacga tccgcgacga ccatttttca ccacatcacc aaccacttcg
    37561 atactcgacg gttcgccgac caggcagtaa tcgagacgct cattacgcga cattaacgct
    37621 tcgacgactt ttaccgtacc gttgtgggca ctagcttctt catcagaagt gatcagaaat
    37681 gccagtcgcc ccgtatggtt gggatgttgt gcgacaaaac gttctgccgc taccaccatc
    37741 gccgccagcg agcctttcat atctgccgca ccgcgcccga ataacatgcc gtcacgaatg
    37801 gttggttcaa acggcggatt gatccaacga tcggcgtcgc caggcggcac cacgtcggta
    37861 tgcccggcaa aggctaacgt ttcaccctgc ccacgccatg cccaaaaatt ctgcgtatcg
    37921 gcaaagtcca tgcgttcaac ggtaaaaccg atcgcctgca aacgttcaat caacaaagcc
    37981 tggcatcctg cgtcatcagg actcagggaa gggcggcgaa taagctgttg tgtcagctca
    38041 ataaccgggc acgacataga ctacacctca tggaaaaatt gctgataact ggaatcactg
    38101 aaacccagca gcataggctt accaggcgcg cagagcaatg gacgtttgat aattgcaggc
    38161 atttcagtca ttaatgccgc cgcagaggcc gcatcggtga ttttattgcg ggtggtttcg
    38221 tccagtttac gccaggttgt accacgggtg ttcagtaacg cttcccagcc taattcgttg
    38281 ataaaaccgt tcaataattc gctgtccagc ccatcgacgc ggtaatcatg aaaacgatag
    38341 tcgatgttat tggcttccag ccaacggcga gcctttttaa tggtgtcaca atttttgatg
    38401 ccgtaaagtg taaccataat gaatcctttt tcgatctatg agaataaata ctcatttaag
    38461 ggtgaaaaca ttttgcctgc aaatgattat caggaaatat aacattatcg aagtattcaa
    38521 attaacaact attaaataat attaaacatt tttaacgtaa acattaagaa tattcatctt
    38581 gttatctgtc tgtattttaa ccagaattaa atcagtatta gatgccgtat gaatatctcg
    38641 aaatgttgct gtgtatcaca tacaaattat caccgcagga ccatagtatt tacataaggt
    38701 ttgtcccccg gaggtagtca tcgcagcaat cgagtaaatt agcttcacca cggtatattg
    38761 tttccgtaga atacccataa ttataagaga ggttgttatg attgaacgtg aactggggaa
    38821 ctggaaagac tttatcgaag ttatgcttcg taagtaattc ctgagacaaa gtacaaacag
    38881 caagaacccg ctgagcaggt tcttaatcgg aaagttgaaa aaggcgacac attagcatgt
    38941 cgcctttttt attgcttatt ccgggcgcgg cttcagcggg aagcggcggc gcaccagtac
    39001 aaagaacagc ggcacgaagt aaatagccag aatagtggcc gaaatcatcc cgcccattac
    39061 gccagtaccc accgcatgct gaccaccgga accggcaccc gtgctggttg ccattggcaa
    39121 tacgccgaag ataaatgcca gcgaggtcat cagaatcggg cgtaaacgct gacggcaggc
    39181 gtggagcgtc gcttcaaaca ggtcgtggcc tttttggttc atctcgttag caaactcgac
    39241 gatcaggatg gcgtttttcg ccgataaacc aatgaccgtt aacaggccca cctggaagta
    39301 aacgtcgttt tccagcccgc gcatccaggt tgccagcagc gcgccgataa cccccagcgg
    39361 cacgaccagc attaccgaga acggcaccga ccagctttca tacaacgccg ccagacacag
    39421 gaataccacc agcaaggaaa tagcgtacag cgccggagcc tgcgcgccgg aaagccgctc
    39481 ctgatacgac atcgccgtcc actccagacc aaagccgttt ggcaactgct tcactaacga
    39541 ttccataata tccatcgccg taccggtact gacccccggt gcggcttccc caacaatctc
    39601 aaccgcagaa taaccgttat agcgttccag acgcggcgag cctgtctccc agcgtgaggt
    39661 cgcgaaagca gagaagggca ccatgccgcc atctttattt cggacatacc agagattgat
    39721 gtcatctggc agcatgcgat acggcgcagc tgcctgcaca tagactttct tcacgcgacc
    39781 gcgatccata aagtcattaa catagctcga accccaggcg gtttgcagtg tgtcgttaat
    39841 atcgtcgata tcaacgccca gcgcctgagc tttacgctgg tcgatatcaa tctgcaactg
    39901 cggactgtcg tcgaggccgt tatggcgcac acgggttagc tccgggtttt ccgccgccag
    39961 caccagcaac tggttacgtg ctgccatcag cgcatcgtga cctgctccag cgtggtcctg
    40021 caactccata tcaaaacccg cagaactacc aagaccgcta attgctggcg ggctgctggc
    40081 gataacgcga gcttctttaa tcttgttaaa cgcctttgtt gcacgctcga taatggcaaa
    40141 cgaggtgccg gtcttactgt cgcgttcgct ccagtctttc aggcggataa acattcgcgc
    40201 cacgttttgc ccgttacccc cggggccaga accaacagtg gcaaacaccg acatgatgtt
    40261 gtctttttca tgggtgaagt aatatttctc gatttgctca acgactttca gggtctgttg
    40321 ttgggttgaa ccgctgggca attgtaccga ggtagtaaac atgccacggt cttccagcgg
    40381 taagaacgac gtcggcaaac gcaggaacag gaacaccatg ccgccaagca gcaggacata
    40441 aatcacaatc cagcgcaggc tacggtggag aattttcgcc accccttttt cgtagcgttc
    40501 ggcgttgcgg ttaaacatct ggttaaacca ggcaaaaaag cctttttgcc cgtgatgctc
    40561 accttttttc agtggcttaa gtagtgtggc acacagagcc ggagtgagga tcatcgctac
    40621 cagtactgac agcaccatcg ccgcaacaat ggtaatagag aactggcgat agatggcacc
    40681 ggtggtgccg ccgaagaagg ccattggtac aaataccgcc gaaagcacca tcgcaatccc
    40741 gaccagtgcc ccctggatct gccccatcga tttacgtgtg gcttcgcgag gagtgagtcc
    40801 ttcctcactc ataatacgtt cgacgttttc caccaccacg atggcgtcat ccaccagcag
    40861 accgatcgcc agcaccatcg cgaacatggt taaggtgttg acgctgtaac caaaggcgta
    40921 aagtacggag aaggttccca tcaacaccac cggcacggcg atagtgggta tcagcgtggc
    40981 gcggaagttt tgcaggaaca gatacataac gaggaaaacc agagcgatag cttccagcag
    41041 cgttttcacc acgtcttcaa tggaggcttt aacaaacgag gtggtttcat acgccacctt
    41101 gtattccagt ccgtgcggga agtactgcgc cagctcgtcg agacgattga gcaccagctc
    41161 cgctgtcgcc atttcgtttg cgccggaggc cagttttacc cccagcccgg aggctggctt
    41221 accattgaag cggctaagat aatcgtattt ctccgccccc atttcgacgg tggcgacatc
    41281 gcccagcctt acctctgagc cgtcttgatt cacccgcaag gtgatatcgc ggaactgttc
    41341 tggtgtttgc agcagtgact gggcgttaat ggtggcgttg agcgcctgct tatcgacgga
    41401 aggtgtacca ccaagttgcc caaccgcaat ctgcgcgttc tgtgactcaa tggcatcagt
    41461 gacatcttta gccgtcatct ggaaactgtt gagtttcgcc gggtccagcc agatacgcat
    41521 ggaatattgc gaaccatagg catcgatatc cccgacgcca ttcacgcggc ttaacgggtc
    41581 ctgaatatta ctggcaacat aatcggcaat atcctgttta tccatcgaac catcggtaga
    41641 gacgaaagca atggtcagaa tattggtatc gccggtttta cgcaccgtca cgccctgatt
    41701 ttgcaccgcc tgcggtaact ttcgcatggc tgattgcagc tggttttgta cttgctgcac
    41761 ggcttcgtcc ggatcggtgc ctgctttaaa acttaaagta acagatgcct gaccggtgcc
    41821 actgctctga gatgacatat acatgagatt atcgaggccg gtcatatttt gctcgataac
    41881 ctgggtcacg gtgttttcca gcgtctgggc cgatgcgccg ggatagttag cggtcactcg
    41941 cacattcggt ggcgcgagat cggggtattg ttcaacgggc aatgagaaaa tcgccagggt
    42001 acctgtcaga cacaacagga ttgccagcac ccaggcaaaa atggggcgat caataaagaa
    42061 attcgccatt aaaagaggac ctcgtgtttc tgcgtatcgt tgtaggcttg acttgcttca
    42121 ctgtagcggc aaggtacgag ccaatcgtgg agaaaaaaag gagttaatgt aaattatcat
    42181 gcccttttat actgaacctt aagtgcaagt attctttggt cagtaggagg cattacatca
    42241 gctgactttc ctcaccctcc gcggagcgaa agctaatact cactaacgtg ccgccgccgg
    42301 aaggttgtga aaaagtcagc gtcccaccca gccgttccgc gcgttcgcgc atgatattca
    42361 gaccataatg accttcgggt tctttcggtt caccgatacc aatcccgtta tcacggatat
    42421 aaaccgtgtg attgccgtcc ggcgcggtga cgcaactgac ggcgatttcg ctggcgttgg
    42481 cgtgcttcat cgcattcagc accgcttcgc gaataatttg caacaaatgc acctgcattt
    42541 gcgcatccag cgccagggtt ggcagacggc agtcgagggt cagtttggcg ctggtttgat
    42601 tttgtaacgt atccagcatt tccctcaacg cggaggggag atccgcctgc tgcagcgtca
    42661 ggcggaaagt agtcaacagc tcgcgtaact gccgataagc atcattcaac gcctgggaaa
    42721 aatcggccat gatactttgt gcggtggcgt tatcttccgg tatcgaacgc ttcagtaacg
    42781 tcaactggat acgtaagtaa gaaagtacct gagccagcga gtcgtgcaat tcgcgggcga
    42841 tggttgcacg ttcttccatc aacaataact gctgaaaatg cttctgcgcc tgattaaagt
    42901 acaaaccgcg tcccagcatc gacgaaacgc tgttaagcag cggttctgat gatgaaacgt
    42961 gactattttg ccagtgcagt tcgccgtaaa ccgtctcttg cattgtcacc ggtaaaatct
    43021 gcatcggcaa ttccgggttt ggttgccctt cgctaatccg ccagttttca ccgacattta
    43081 actccagata ttcagccgct tcattgtcgc gaacaatctg caaaatatgg cggaaacaat
    43141 gcacatcaat ctggctggtg ttcagcgcct gggaacattg atacaacacc tccagacgac
    43201 gcttggcctc gtggagatcg cgggtctttt cttctactga cgcctccagc gaaaggtaca
    43261 atttatgcag ctcgctcgac atctggttaa aggtttttgc aagcagacca agctcattcg
    43321 gcagactggt atccagcggc ggcgagtcga actgtccgtg ttcaatacgc tgactggcgg
    43381 taaccagctg attcagcggg gcaaccacct gatggcgtat gcggcgcaaa gtaaaaaaga
    43441 ccagcgtgaa aataccgata ccgccagcca gggaaatcgc caccaccagc agcattttgc
    43501 gttcagcgta gtgctgtaaa gccagcacga acaggtctat ctgattaaca taattattaa
    43561 tattggcctg ataccacggc aaatcgccct tgctgagccg attattcatc tccagccagt
    43621 tggcattcag atgcgcatag cgagttttta ctgcttctgg cacataccag acgttgagat
    43681 tggttaatac cggtgaatgc agtgcctgct gaaacaactg gcgatgtgca ttgagttgtg
    43741 gactgccact ttgcaagtcg tagcccaggc ggtaactctg catacgcagc gatccggcaa
    43801 tattaatagc ctcagcgtcg cgcaaactgc tcgccagagt tagcagagcg atacccgtgg
    43861 aaagaatcga cagcagcaca atgtaaaaaa aggcccgggc cagactggcc gagacgggtc
    43921 gtttaacaat cacacgcgtc ttctccacaa aaaatcatta atgttccagt tcgctgaaac
    43981 acaatttagt cagtgatggg attatttgat ctgccacagt ttatagcgaa atagttactt
    44041 attctgggca catgaacatt gccgattccc ctgtaagtcg ggtaataaca acactcatat
    44101 aaagaataag gtttttacaa ccaaaaaaga aggtcgttat gaatcgtttt attatggcca
    44161 acagtcagca atgtctgggt tgtcatgctt gtgaaatcgc ctgtgtcatg gctcacaatg
    44221 atgagcaaca tgtcctgagc caacaccatt ttcatccccg aattacggtt atcaaacatc
    44281 aacagcaacg tagtgcagtg acctgtcacc attgtgaaga tgcgccctgc gcccgtagct
    44341 gccctaatgg cgcaatcagc cacgttgatg acagcattca ggtcaatcag caaaagtgta
    44401 ttggctgtaa atcctgcgtg gtggcctgtc cttttggtac gatgcaaatc gtcctgacac
    44461 ccgtcgcggc aggaaaagta aaagccacgg cgcataaatg cgacctttgt gcggggcgcg
    44521 aaaacggtcc tgcctgtgtt gagaattgcc cggcggacgc gctgcaactg gtcactgacg
    44581 tcgcactctc cggcatggcg aaatcccgcc gcttgcgcac cgcgcgtcag gaacatcaac
    44641 cgtggcatgc cagtaccgcg gcgcaagaaa tgccggtaat gagtaaagtc gaacaaatgc
    44701 aggcaacgcc cgcgcgtggc gagccggata aactggcgat tgaagcgcgc aaaaccggtt
    44761 ttgatgaaat ttatctgcca tttcgcgccg accaggcaca acgggaagcc tcgcgctgcc
    44821 ttaagtgcgg cgagcacagc gtttgtgaat ggacctgccc gctgcataac catataccgc
    44881 agtggattga actggtgaaa gccggaaaca tcgacgccgc cgtcgagctt tctcaccaga
    44941 ccaacaccct gccggaaatt accggacgcg tttgtccgca agaccgtttg tgtgaaggtg
    45001 cctgtactat tcgcgatgag cacggcgcgg taactatcgg caacattgaa cgctatattt
    45061 cagatcaggc gttggcgaaa ggttggcgtc ctgacttaag tcatgtcacc aaagtggaca
    45121 agcgggtggc gattatcggg gcaggtccgg cagggctggc ctgtgcggat gttctgaccc
    45181 gcaatggcgt ggcggtgacg gtgtacgatc gccatccaga aatcggtggc ttgctcactt
    45241 tcggcattcc ttctttcaaa ctggataaat ccctgctggc acgccgtcgg gaaatcttca
    45301 gcgcgatggg gattcacttc gaactcaatt gtgaagtggg taaagatgtc tctttggatt
    45361 cgcttttgga acaatacgac gcggtcttcg ttggcgtagg cacttaccgt tccatgaaag
    45421 cgggtttacc caatgaagat gcgccgggcg tttatgacgc gctgccgttc ctcattgcca
    45481 acactaaaca ggtgatgggg ctcgaagagc taccggaaga gccgtttatc aataccgccg
    45541 gacttaacgt cgtggtactg ggcggcggcg acaccgcgat ggactgtgtg cgtaccgcac
    45601 tgcgccacgg cgcgagtaac gtcacctgcg cttatcgtcg tgatgaagct aacatgccag
    45661 gctcgaagaa agaagtgaag aacgcccgcg aagagggggc caacttcgaa tttaacgtcc
    45721 agccggtggc gcttgagctg aatgaacaag gtcacgtttg cggaattcgt ttcctgcgca
    45781 cgcgtcttgg cgagccggat gcccaggggc gtcggcgacc tgtaccgatt gagggcagtg
    45841 aatttgtcat gccagccgat gcggtgatta tggcgtttgg cttcaatcca cacgggatgc
    45901 cgtggctgga gtcgcacggt gtaacggtag acaaatgggg ccgcatcatc gcggatgtgg
    45961 aaagccagta ccgttaccag accaccaatc cgaaaatctt cgccggtggc gacgccgtgc
    46021 gtggtgcgga tctggtggtt accgcaatgg cagaaggacg tcatgcggca cagggcatta
    46081 ttgactggct gggggtaaaa tcagtcaaat ctcactgata gcctgcgcag acaaacccga
    46141 cttcacagcg taagataatt gttcatttcg cgctgtggag tcgctatgac gcaacaaatc
    46201 accctcatta aagacaaaat tctctccgat aactatttca ccctgcacaa cattacttac
    46261 gatctcacgc gcaaagatgg cgaagttatc cgccataaac gtgaagttta cgatcgcggt
    46321 aatggtgcga cgatcctcct gtacaacgcg aagaaaaaga ccgtggttct gattcgtcag
    46381 ttccgcgtcg ctacctgggt taatggcaat gaaagtgggc agctgattga aacctgcgcc
    46441 gggctgctgg ataacgacga accgaaagtg tgcattcgca aagaagcgat tgaagagacg
    46501 ggctatgaag tgggcgaagt gcgcaaatta tttgaactgt atatgtcgcc tggcggtgtg
    46561 actgagctaa tccacttttt tatcgccgaa tacagtgaca atcagcgcgc taacgccggt
    46621 ggcggtgttg aagatgaaga tattgaagtg ctcgagctgc cgttcagcca ggcgctggag
    46681 atgatcaaaa ccggcgagat acgtgacggt aagacggtgt tattgcttaa ctatttgcaa
    46741 acgtcacatt taatggactg aaaaataaca ataatatttc gttgtttatt attggctcaa
    46801 tccgacaaat ctgattgagc cgcgctacct gcgcaacgaa gatacgactt gtgctgtttg
    46861 tttgaacttc tggggtcgta ccgtccatgc gctatcgcat tttccttctc ttttttttcg
    46921 ctttgttgcc gacgtctttg gtgtgggcgg caccagcgca acgggcgttt tccgactggc
    46981 aggtcacctg taataaccaa aacttctgcg tggcgcgcaa tacgggcgat cataatggac
    47041 tggtgatgac cctgagccgc agcgccgggg cgcataccga tgccgtttta cgtattgagc
    47101 gcggcgggtt gaagtcgccg gatgcgtctg aaggagagat agcgccacgg ctgctgttag
    47161 atggtgagcc gttggcgtta agtggtgaca agtggcggat ttcaccatgg ttattagtaa
    47221 ccgatgatac ggcaaccatc accgcgtttt tgcagatgat tcaggaaggg aaggcgatca
    47281 ccttacgcga cggcaatcag accatttctc tgagtggctt aaaagcggcg ttgttgttta
    47341 ttgatgctca gcaaaagcgc gttggcagtg aaaccgcgtg gatcaagaaa ggggacgaac
    47401 cgccgctcag cgtaccgccc gcgcctgcgc tgaaagaggt cgcggtggtt aacccaacgc
    47461 cgacgccact ctcactcgaa gaacgcaacg atttgctgga ttatggaaac tggcggatga
    47521 atggtctgcg ctgctcgctt gatccgttac gtcgtgaggt gaatgtcact gcgctgactg
    47581 atgataaagc gctgatgatg attagctgtg aggcaggggc ctataacacc attgatttgg
    47641 catggattgt gtcgcgtaaa aagccactag cctcgcgccc ggttcggttg cgtttgccgt
    47701 tcaacaacgg tcaggagacg aatgaactgg aactgatgaa cgcaacattt gatgagaaat
    47761 cgcgtgaact ggtgacctta gcgaaagggc gcggattaag cgattgtggc attcaggcgc
    47821 gctggcgctt tgacggtcag cgttttcgcc tggtgcgtta tgccgcagaa cccacctgcg
    47881 ataactggca tgggccagac gcctggccca cgttgtggat cacccgttaa acaaaattgc
    47941 ggggacatgt aggccggata agacgctgta ggccggataa gacgcgtcag cgtcgcatcc
    48001 ggcaatcagc atccggcgat caccatcagg cacctttcac tcccagcacc ttatgcgctt
    48061 ttgccacaat attctcggcg gtaaagccaa agaacgggaa cagcttatcc gccggagcag
    48121 attccccgta acccgtcatc ccgacaattg cccctttcag accaacatac ttgtaccagt
    48181 aatcggcaat acctgcttcc accgccacgc gagccgcaac gttagaaggc aacaccgact
    48241 cccgatattc ctcatcctgg gcgtcgaaaa tatcggtcga gggcagggaa actacgcgta
    48301 cattgcgacc ttctcctgct aatttctctg ccgcttgcag ggtaatttcc atctctgaac
    48361 cggtggcaat cagaataata tctggcttac cgccgctgtc tttcagcaca taaccgccac
    48421 gagcaatctc tttaacctga tccggcgtac gttccacctg ggccagattc tgccttgaga
    48481 ggatcagtgc cgtcggtccg ttgtggcgct caaccgccag cttccagccc accgccgctt
    48541 ccacctgatc gcacggtcgc caggtgctga aatttggcgt taagcgcagg ctggccagtt
    48601 gctcaacagc ctggtgcgtc ggaccatctt cgcccaggcc aattgagtcg tgggtataaa
    48661 ccataatctg ccgcgctttc atcagtgccg ccatccgcgc ggcgttacgg gcgtattcaa
    48721 caaacatcag gaacgtcgcg gtatacggca caaagccgcc gtggtgcgcg atgccgttgg
    48781 cgatagcggt catgccaaat tcacgcaccc cgtagtgaat gtagttgccc gctggatctt
    48841 ccttcagcga aacagaacct ttccagatgg tcaggttgct gggagccaga tccgccgaac
    48901 cgccgagcaa ctcaggcagc atcggcccgt aagcgttaag cgtattttgc gaagccttac
    48961 gggtagcgat tttcgccgga tttgcctgta actcattgat atatttctga gtcgttttct
    49021 cccagtcctt cggtaaacca ccgctcatcc gtcgggtaaa ctcttctgcc agttgcggat
    49081 gagccttttt ataggcggca aacttctcat tccagctctg ctgcgctttt tcgccttttt
    49141 cacgggcatc ccaggcgtga taaatctttt tagggatctc aaatggcgga tggtgccagc
    49201 ccagtttttg ccgtgccagc gccacttctt cttcccccag tggtgcgccg tgcgcctctt
    49261 ccttacctgc tttattcggc gaaccaaagc caatcaccgt acggcagata atcagcgacg
    49321 gcttatcttt cacgctttgc gcttcaagga tcgcttcctt caccgcctgc ggatcgtgac
    49381 cgtcgatttc atggatcaca tgccagtgat aggcttcaaa acgttttgcc gtatcgtcgg
    49441 taaaccagcc ttctgtttca ccgtcgatgg aaataccgtt gtgatcgtaa aaaccaatca
    49501 gcttgcccag tcccagcgtg cctgccagcg aacagacttc gtgggaaata ccttccatca
    49561 ggcagccgtc gcccataaac acataggtga agtgatcgac gatctcatgg tctggctggt
    49621 taaactgcgc cgccagtgta cgttccgcta tcgccagccc gacggcgttc gccaaacctt
    49681 gtccaagcgg gccggtggtg gtttcaacgc ctggcgtata gccaatctcc gggtggcctg
    49741 gggttttcga atgcaactga cggaagttct tcagttcttc cagcggcagg tcgtaaccgg
    49801 tcagatgtag caaactgtag agcagcatcg acgcgtgacc gttggaaaga ataaagcggt
    49861 cgcgatcata ccaggttggg tcggtagggt tatgtttaag aaaatcgttc cacagcactt
    49921 cggcaatatc agccatgccc atcggcgcgc cgggatgacc agaattggct ttttgtaccg
    49981 catccatact gagtgcgcga atcgcattgg caaggtcttt tcgggacata taacactccg
    50041 tggctggttt atagtttggc ggcaagaaga tcttccagtt tgcgttgatc aacagcgaac
    50101 agacgaatgc cttcagacag tttttctacc gccatcgcat cctgattgtg ctcccaacgg
    50161 aactccgctt cgctcatggg agctgggcgt gggaacgtct gagaaggtgg gattaattta
    50221 cgtaccactg gcgaaacttt ttcctgcagc tccttcagca aattcggtgc gatagtcagt
    50281 cgatcgcagc cggttaaggc gaggatttgt tcggtgcgac ggaagctcgc gcccatcaca
    50341 atggtttcat agtggtgttg cttatagtag tcgtagatat tgcgcaccga tttaacgccc
    50401 ggatcttctt ccaccacata cgggtccatc ggcttgcgtg cctgatacca gtcataaata
    50461 cgcccgacaa acggcgaaat cagaaaaacg cccgcttctg cacaggcccg cgcctgggca
    50521 aaagaaaata gcagcgtcag gttgcagtta ataccttctt tttccagctc ttcggccgcg
    50581 cgaattcctt cccaggtcga agccagtttg atcaaaatgc gtgatttctc aacgccttgt
    50641 tgctgataca agtccaccag atggcgcgcc ttctcaatac tcttttcttt atcaaaagag
    50701 aggcgtgcat caacttctgt tgacacgcga ccgggtacga ttttgagaat ttcagcaccg
    50761 aaattgactg ccagtttgtc acacgctgcg accacctgtt gttcctgggt cttgccattt
    50821 tttttacccc aggcgatagc atcgtctatt aaatgctcat attgtgataa tccggcagct
    50881 ttgagtaaca gcgaaggatt ggtggtggca tcctggggat gataatggcg aatggactca
    50941 atatcgccgc tgtctgccac gacagtggtg aactgtttga tgccgtctaa ctcgttcata
    51001 ggaaatactc cttgaaaagt aaagtgttag atgagtgcgt taattcacac ttctgagaaa
    51061 tttcgctaaa cgcatcaaaa aagcatagca gacaggcatg gtattgctgg attaagcagg
    51121 taacatcagt gttataggat tattaccaaa acattatatt aatggtgaga gtttggactt
    51181 gctcaaagtc tgtagactcc ggcagggtaa taatgtgcgc cacgttgtgg gcaggggctg
    51241 ttgcccacac actttatttg tgaacgttac gtgaaaggaa caaccaaatg gatgaccagt
    51301 taaaacaaag tgcacttgat ttccatgaat ttccagttcc agggaaaatc caggtttctc
    51361 caaccaagcc tctggcaacg cagcgcgatc tggcgctggc ctactcacca ggcgttgccg
    51421 caccttgtct tgaaatcgaa aaagacccgt taaaagccta caaatatacc gcgcgcggta
    51481 acctggtggc ggtgatctct aacggtacgg cggtgctggg gttaggcaac attggcgcgc
    51541 tggctggcaa accggtgatg gaaggcaagg gcgttctgtt taagaaattc gccgggattg
    51601 atgtatttga cattgaagtt gatgaactcg acccggacaa atttattgaa gttgtcgctg
    51661 cgctcgaacc gaccttcggc ggaatcaacc tcgaagacat taaagcgcca gaatgtttct
    51721 atattgaaca gaaactgcgc gagcggatga atattccggt attccacgac gatcagcacg
    51781 gcacggcaat catcagcact gccgccatcc tcaacggctt gcgcgtggtg gagaaaaaca
    51841 tctccgacgt gcggatggtg gtttccggcg cgggtgccgc agcaatcgcc tgtatgaacc
    51901 tgctggtagc gctgggtctg caaaaacata acatcgtggt ttgcgattca aaaggcgtta
    51961 tctatcaggg ccgtgagcca aacatggcgg aaaccaaagc cgcatatgcg gtggtggatg
    52021 acggcaaacg taccctcgat gatgtgattg aaggcgcgga tattttcctt ggatgttccg
    52081 gcccgaaagt gctgacccag gaaatggtga agaaaatggc tcgtgcgcca atgatcctgg
    52141 cgctggcgaa cccggaaccg gaaattctgc cgccgctggc gaaagaagtg cgtccggatg
    52201 ccatcatttg caccggtcgt tctgactatc caaaccaggt caacaacgtc ctttgcttcc
    52261 cgtttatctt ccgtggcgcg ctggatgttg gcgcaacggc tatcaatgaa gagatgaaac
    52321 tggcggcggt acgcgcgatt gcggaactgg cccacgccga acagagcgaa gtggtggctt
    52381 cagcgtatgg cgatcaggat ctgagctttg gtccggaata catcattcca aaaccgtttg
    52441 atccgcgctt gatcgttaag atcgctcctg cggtggcgaa agcggcgatg gagtcgggcg
    52501 tggcgacgcg tccgattgct gatttcgacg tctacatcga caagctgact gagttcgttt
    52561 acaaaaccaa cctgtttatg aagccgattt tctcccaggc tcgcaaagcg ccgaagcgcg
    52621 tagttctgcc ggaaggggaa gaggcgcgcg ttctgcatgc cactcaggaa ctggtaacgc
    52681 tgggactggc gaaaccgatc cttatcggtc gtccgaacgt gatcgaaatg cgcattcaga
    52741 aactgggctt gcagatcaaa gcgggcgttg attttgagat cgtcaataac gaatccgatc
    52801 cgcgctttaa agagtactgg accgaatact tccagatcat gaagcgtcgc ggtgtcactc
    52861 aggaacaggc gcagcgggcg ctgatcagta acccgacagt gatcggcgcg atcatggttc
    52921 agcgtgggga agccgatgca atgatctgcg gtacggtggg cgattatcat gaacatttta
    52981 gcgtggtgaa aaatgtcttt ggttatcgcg atggcgttca caccgcaggt gcaatgaacg
    53041 cgctgctgct gccgagtggt aacaccttta ttgccgatac ctacgtcaat gacgaaccag
    53101 acgcagaaga gctggcggag atcaccttga tggcggcaga aactgtccgt cgttttggta
    53161 ttgagccgcg cgttgctctg ttgtcgcact ccaactttgg ttcttctgac tgcccgtcgt
    53221 cgagcaaaat gcgtcaggcg ctggaactgg tcagggatcg tgcgccagat ctgatgattg
    53281 atggtgaaat gcacggcgat gcagcgctgg tggaagcgat tcgcaacgac cgtatgccgg
    53341 acagcccttt gaaaggttct gccaatattc tggtgatgcc gaacatggaa gctgcccgca
    53401 ttagttacaa cttactgcgc gtttccagct cggaaggtgt gactgtcggt ccggtgctga
    53461 tgggcgtggc gaaaccggtt cacgtgttaa cgccgatcgc atcggtgcgt cgtatcgtca
    53521 acatggtggc gctggccgtg gttgaagcgc aaacccaacc gctgtaattc ttttttaact
    53581 ctcacgctta ccctgaatat tcagggtaag cggtttggct gcaatatatt agtaaagctt
    53641 attactgagt ttg
//
LOCUS       DAPOAV010000022        51505 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.022, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000022 DAPOAV010000000
VERSION     DAPOAV010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 51505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51505
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.022"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            42..743
                     /locus_tag="RN951_001563"
     CDS             42..743
                     /locus_tag="RN951_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDX2526578.1"
                     /translation="MKTCITKGIVTVSLTAILLSCSSAWAAGKGGIGLAATRLVYSEG
                     EEQISLGVRNTSPDVPYLIQSWVMTPDNKKSADFIITPPLFVLNPANENLLRIMYIGA
                     PLAKDRETLFFTSVRAVPSTTKRKEGNTLKIATQSVIKLFWRPKGLAYPLGEAPAKLR
                     CTSSADMVTVSNPTPYFITLTDLKIGGKVVKNQMISPFDKYQFSLPKGAKNSSVTYRT
                     INDYGAETPQLNCKS"
     gene            768..3368
                     /locus_tag="RN951_001564"
     CDS             768..3368
                     /locus_tag="RN951_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis usher protein"
                     /protein_id="HDX2526579.1"
                     /translation="MYRTHRQHSLLSSGGVPSFIGGLVVFVSAAFNAQAETWFDPAFF
                     KDDPSMVADLSRFEKGQKITPGVYRVDIVLNQTIVDTRNVNFVEITPEKGIAACLTTE
                     SLDAMGVNTDAFPAFKQLDKQACVPLAEIIPDASVTFNVNKLRLEISVPQIAIKSNAR
                     GYVPPERWDEGINALLLGYSFSGANSIHSSADSDSGDSYFLNLNSGVNLGPWRLRNNS
                     TWSRSSGQTAEWKNLSSYLQRAVIPLKGELTVGDDYTAGDFFDSVSFRGVQLASDDNM
                     LPDSLKGFAPVVRGIAKSNAQITIKQNGYTIYQTYVSPGAFEISDLYSTSSSGDLLVE
                     IKEADGSVNSYSVPFSSVPLLQRQGRIKYAVTLAKYRTNSNEQQESKFAQATLQWGGP
                     WGTTWYGGGQYAEYYRAAMFGLGFNLGDFGAISFDATQAKSTLADQSEHKGQSYRFLY
                     AKTLNHLGTNFQLMGYRYSTSGFYTLSDTMYKHMDGYEFNDGDDEDTPMWSRYYNLFY
                     TKRGKLQVNISQQLGEYGSFYLSGSQQTYWHTDQQDRLLQFGYNTQIKDLSLGISWNY
                     SKSRGQPDADQVFALNFSLPLNLLLPRSNDSYTRKKNYAWMTSNTSIDNEGHTTQNLG
                     LTETLLDDGNLSYSVQQGYNSEGKTANGSASMDYKGAFADARVGYNYSDNGSQQQLNY
                     ALSGSLVAHSQGITLGQSLGETNVLIAAPGAENTRVANSTGLKTDWRGYTVVPYATSY
                     RENRIALDAASLKRNVDLENAVVNVVPTKGALVLAEFNAHAGARVLMKTSKQGIPLRF
                     GAIATLDGVQANSGIIDDDGSLYMAGLPAKGTISVRWGEAPDQICHINYELTEQQINS
                     AITRMDAICR"
     gene            3359..4429
                     /locus_tag="RN951_001565"
     CDS             3359..4429
                     /locus_tag="RN951_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX2526580.1"
                     /translation="MQIIFGEKCVSLLRLFFAAVLMLWCAQTAAYSGQCHTTQGNPYI
                     GVNFGVKTLEEEANTAGVVKDKFYQWNESNDYYVSCDCDKDNVRSGRWAFAADSPLVY
                     LGDNWYKINDYLAAKVLLQVKGSSPTAVPFENVGTGGDTRWHICDPGGQRLGGQGASG
                     NSGSFSLKILQPFVGSVVIPPMALARLYECYNIPAGDSCTTTGTPVLVYYLSGTINSL
                     GSCSVNAGETIEVDLGDVFAANFRVVGHKPLGARTAELAIPVRCNTGNAGLVNVNLSL
                     TATTDPSYPQAIKTSRPGVGVVVTDSQNNIISPAGGTLPLSIPDDADSIARMNVYPVS
                     TTGVPPETGRFEATATVRINFD"
     gene            4441..4983
                     /locus_tag="RN951_001566"
     CDS             4441..4983
                     /locus_tag="RN951_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX2526581.1"
                     /translation="MKKKTIFQCVILFFSILNIHVGMAGPEQVSMHIYGNVVDQGCDV
                     ATKSALQNIHIGDFNISDFQAANTVSTAADLNIDITGCAAGITGADVLFSGEADTLAP
                     TLLKLTDTGGSGGMATGIAVQILDAQSQQEIPLNQVQPLTPLKAGDNTLKYQLRYKST
                     KAGATGGNATAVLYFDLVYQ"
     gene            4991..5506
                     /locus_tag="RN951_001567"
     CDS             4991..5506
                     /locus_tag="RN951_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415463.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDX2526582.1"
                     /translation="MLKRIIWILFLLGLTWGCELFAHDGTVNISGSFRRNTCVLAQDS
                     KQINVQLGDVSLTRFSHGNYGPEKSFIINLQDCGTDVSTVDVTFSGTPDGVQSEMLSI
                     ESGTDAASGLAIAILDDAKILIPLNQASKDYSLHSGKVPLTFYAQLRPVNSDVQSGKV
                     NASATFVLHYD"
     gene            5472..6209
                     /locus_tag="RN951_001568"
     CDS             5472..6209
                     /locus_tag="RN951_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HDX2526583.1"
                     /translation="MPARHLYFIMTNTWNRLALLIFAVLSLLVAGELQAGVVVGGTRF
                     IFPADRESISILLTNTSQESWLINSKINRPTRWAGGEASTVPAPLLAAPPLILLKPGT
                     TGTLRLLRTESDILPVDRETLFELSIASVPSGKVENQSVKVAMRSVFKLFWRPEGLPG
                     DPLEAYQQLRWTRNSQGVQLTNPTPYYINLIQVSVNGKALSNMGVVPPKSQRQTSWCQ
                     AIAPCHVAWRAINDYGGLSAKKEQNLP"
     gene            6320..7330
                     /gene="pyrD"
                     /locus_tag="RN951_001569"
     CDS             6320..7330
                     /gene="pyrD"
                     /locus_tag="RN951_001569"
                     /EC_number="1.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent dihydroorotate dehydrogenase"
                     /protein_id="HDX2526584.1"
                     /translation="MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPFEALVRQKVPA
                     KPVNCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFR
                     LVDAEGLINRMGFNNLGVDNLVENVKKAHYDGVLGINIGKNKDTPVEQGKDDYLICME
                     KIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQAMHHKYVPIAVKI
                     APDLSEEELIQVADSLVRHNIDGVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKST
                     EIIRRLSLELNGRLPIIGVGGIDSVIAAREKIAAGASLVQIYSGFIFKGPPLIKEIVT
                     HI"
     gene            7504..8046
                     /gene="zapC"
                     /locus_tag="RN951_001570"
     CDS             7504..8046
                     /gene="zapC"
                     /locus_tag="RN951_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415466.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapC"
                     /protein_id="HDX2526585.1"
                     /translation="MRIKPDDNWRWYYDEEHDRMMLDLANGMLFRSRFARKMLTPDAF
                     SPAGFCVDDAALYFSFEEKCRDFNLSKEQKAELVLNALVAIRYLKPQMPKSWHFVSHG
                     EMWVPMPGDAACVWLSDTHEQVNLLVVESGENAALCLLAQPCVVIAGRAMQLGDAIKI
                     MNDRLKPQVNVDSFSLEQAV"
     gene            complement(8043..9152)
                     /gene="ycbX"
                     /locus_tag="RN951_001571"
     CDS             complement(8043..9152)
                     /gene="ycbX"
                     /locus_tag="RN951_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-N-hydroxylaminopurine resistance protein YcbX"
                     /protein_id="HDX2526586.1"
                     /translation="MATLIRLFIHPVKSMRGIGLTHALADVSGLAFDRIFMITEPDGT
                     FITARQFPQMVRFTPSPVHDGLHLTAPDGSSAYVRFADFATQDAPTEVWGTHFTARIA
                     PDAINKWLSEFFSREVQLRWVGPQMTRRVKRHNTVPLSFADGYPYLLANEASLRDLQQ
                     RCPASVKMEQFRPNLVVSGASAWEEDRWKVIRIGDVVFDVVKPCSRCIFTTVSPEKGQ
                     KHPAGEPLKTLQSFRTAQDNGDVDFGQNLIARNSGVIRVGDEVEILATAPAKIYGAAA
                     ADDTANITQQPDANVDIDWQGQAFRGNNQQVLLEQLENQGIRIPYSCRAGICGSCRVQ
                     LLEGEVTPLKKSAMGDDGTILCCSCVPKTALKLAR"
     gene            9396..11504
                     /gene="rlmKL"
                     /locus_tag="RN951_001572"
     CDS             9396..11504
                     /gene="rlmKL"
                     /locus_tag="RN951_001572"
                     /EC_number="2.1.1.173"
                     /EC_number="2.1.1.264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 23S rRNA
                     (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA
                     (guanine(2445)-N(2))-methyltransferase RlmL"
                     /protein_id="HDX2526587.1"
                     /translation="MNSLFASTARGLEELLKTELENLGAVECQVVQGGVHFKGDTRLV
                     YQSLMWSRLASRIMLPLGECKVYSDLDLYLGVQAINWTEMFNPGATFAVHFSGLNDTI
                     RNSQYGAMKVKDAIVDAFTRKNLPRPNVDRDAPDIRVNVWLHKETASIALDLSGDGLH
                     LRGYRDRAGIAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMLATDRAPGL
                     HRGRWGFSGWAQHDEAIWQEVKAEAQTRARKGLAEYSSHFYGSDSDARVIQRARTNAR
                     LAGIGELITFEVKDVAQLTNPLPKGPYGTVLSNPPYGERLDSEPALIALHSLLGRIMK
                     NQFGGWNLSLFSASPDLLSCLQLRADKQYKAKNGPLDCVQKNYHVAESTPDSKPAMVA
                     EDYTNRLRKNLKKFEKWARQEGIECYRLYDADLPEYNVAVDRYADWVVVQEYAPPKTI
                     DAHKARQRLFDIIAATISVLGIAPNKLVLKTRERQKGKNQYQKLGEKGEFLEVTEYNA
                     HLWVNLTDYLDTGLFLDHRIARRMLGQMSKGKDFLNLFSYTGSATVHAGLGGARSTTT
                     VDMSRTYLEWAERNLRLNGLTGRAHRLIQADCLAWLREANEQFDLIFIDPPTFSNSKR
                     MEDAFDVQRDHLALMKDLKRLLRAGGTIMFSNNKRGFRMDLDGLAKLGLKAQEITQKT
                     LSQDFARNRQIHNCWLITAA"
     gene            11516..13423
                     /locus_tag="RN951_001573"
     CDS             11516..13423
                     /locus_tag="RN951_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX2526588.1"
                     /translation="MSLISMHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKST
                     LMKILNREQGLDDGRIIYEQDLIVARLQQDPPRNVEGSVYDFVAEGIEEQAEYLKRYH
                     DISRLVMNDPSEKNLNELAKVQEQLDHHNLWQLENRINEVLAQLGLDPNVALSSLSGG
                     WLRKAALGRALVSNPRVLLLDEPTNHLDIETIDWLEGFLKTFNGTIIFISHDRSFIRN
                     MATRIVDLDRGKLVTYPGNYDQYLLEKEEALRVEELQNAEFDRKLAQEEVWIRQGIKA
                     RRTRNEGRVRALKAMRRERGERREVMGTAKMQVEEASRSGKIVFEMEDVCYQVNGKQL
                     VKDFSAQVLRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHVGTKLEVAYFDQHRA
                     ELDPDKTVMDNLAEGKQEVMVNGKPRHVLGYLQDFLFHPKRAMTPVRALSGGERNRLL
                     LARLFLKPSNLLILDEPTNDLDVETLELLEELIDSYQGTVLLVSHDRQFVDNTVTECW
                     IFEGGGKIGRYVGGYHDARGQQEQYVALKQPAVKKTEEAAAAKAETVKRSSSKLSYKL
                     QRELEQLPQLLEDLEAKLEALQTQVADASFFSQPHEQTQKVLADMAAAEQELEQAFER
                     WEYLEALKNGG"
     gene            13553..14806
                     /gene="pqiA"
                     /locus_tag="RN951_001574"
     CDS             13553..14806
                     /gene="pqiA"
                     /locus_tag="RN951_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiA"
                     /protein_id="HDX2526589.1"
                     /translation="MCEHHHAAKHILCSQCDMLVALPRLEHGQKAACPRCGTTLTVAW
                     DAPRQRPTAYALAALFMLLLSNLFPFVNMNVAGVTSEITLLEIPGVLFSEDYASLGTF
                     FLLFVQLVPAFCLITILLLVNRAELPVRLKEQLARVLFQLKTWGMAEIFLAGVLVSFV
                     KLMAYGSIGVGSSFLPWCLFCVLQLRAFQCVDRRWLWDDIAPMPELRQPLKPGVTGIR
                     QGLRSCSCCTAILPADEPVCPRCSTKGYVRRRNSLQWTLALLVTSIMLYLPANILPIM
                     VTDLLGSKMPSTILAGVILLWSEGSYPVAAVIFLASIMVPTLKMIAIAWLCWDAKGHG
                     KRDSERMHLIYEVVEFVGRWSMIDVFVIAVLSALVRMGGLMSIYPAMGALMFALVVIM
                     TMFSAMTFDPRLSWDRQPESEHEES"
     gene            14811..16451
                     /gene="pqiB"
                     /locus_tag="RN951_001575"
     CDS             14811..16451
                     /gene="pqiB"
                     /locus_tag="RN951_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intermembrane transport protein PqiB"
                     /protein_id="HDX2526590.1"
                     /translation="MESNNGEAKIQKVKNWSPVWIFPIVTALIGAWVLFYHYSHQGPE
                     VTLITANAEGIEGGKTTIKSRSVDVGVVESATLADDLTHVEIKARLNSGMEKLLHKDT
                     VFWVVKPQIGREGISGLGTLLSGVYIELQPGAKGSKMDKYDLLDSPPLAPPDAKGIRV
                     ILDSKKAGQLSPGDPVLFRGYRVGSVETSTFDTQKRNISYQLFINAPYDRLVTNNVRF
                     WKDSGIAVDLTSAGMRVEMGSLTTLLSGGVSFDVPEGLDLGQPVAPKTAFVLYDDQKS
                     IQDSLYTDHIDYLMFFKDSVRGLQPGAPVEFRGIRLGTVSKVPFFAPNMRQTFNDDYR
                     IPVLIRIEPERLKMQLGENADVVEHLGELLKRGLRGSLKTGNLVTGALYVDLDFYPNT
                     PAITGIREFNGYQIIPTVSGGLAQIQQRLMEALDKINKLPLNPMIEQATSTLSESQRT
                     MKNLQTTLDSMNKILASQSMQQLPTDMQSTLRELNRSMQGFQPGSAAYNKMVADMQRL
                     DQVLRELQPVLKTLNEKSNALVFEAKDKKDPEPKRAKQ"
     gene            16448..17011
                     /gene="pqiC"
                     /locus_tag="RN951_001576"
     CDS             16448..17011
                     /gene="pqiC"
                     /locus_tag="RN951_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiC"
                     /protein_id="HDX2526591.1"
                     /translation="MKKWLVTIAALWLAGCSSGEINKNYYQLPVVQSGTQSTASQGNR
                     LLWVEQVTVPDYLAGNGVVYQTSDVKYVIANNNLWASPLDQQLRNTLVANLSTQLPGW
                     VVASQPLGSAQDTLNVTVTEFNGRYDGKVIVSGEWLLNHQGQLIKRPFRLEGVQTQDG
                     YDEMVKVLAGVWSQEAASIAQEIKRLP"
     gene            17267..17434
                     /gene="rmf"
                     /locus_tag="RN951_001577"
     CDS             17267..17434
                     /gene="rmf"
                     /locus_tag="RN951_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome modulation factor"
                     /protein_id="HDX2526592.1"
                     /translation="MKRQKRDRLERAHQRGYQAGIAGRSKEMCPYQTLNQRSQWLGGW
                     REAMADRVVMA"
     gene            complement(17504..18022)
                     /gene="fabA"
                     /locus_tag="RN951_001578"
     CDS             complement(17504..18022)
                     /gene="fabA"
                     /locus_tag="RN951_001578"
                     /EC_number="4.2.1.59"
                     /EC_number="5.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014915875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-hydroxydecanoyl-ACP
                     dehydratase/trans-2-decenoyl-ACP isomerase"
                     /protein_id="HDX2526593.1"
                     /translation="MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMT
                     ETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEG
                     KGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTASD
                     LKVGLFQDTSAF"
     gene            complement(18091..19851)
                     /locus_tag="RN951_001579"
     CDS             complement(18091..19851)
                     /locus_tag="RN951_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lon protease family protein"
                     /protein_id="HDX2526594.1"
                     /translation="MTIKKLAWRDLVPDTDSYQEIFAQPHLIDENDPLFSDTQPRLQF
                     ALEQLLHTRASSSFMLAKAPEESEYLNLIANAARTLQSDAGQLVGGHYEVSGHSIRLR
                     HAVSADDNFATLTQVVAADWVEAEQLFGCLRQFNGDITLQPGLVHQANGGILIISLRT
                     LLAQPLLWMRLKNIVNRERFDWVAFDESRPLPVSVPSMPLKLKVILVGERESLADFQE
                     MEPELSEQAIYSEFEDTLQIVDAESVTQWCRWVTFTARHNHLPAPGADAWPILIREAA
                     RYTGEQETLPLSPQWILRQCKEVASLCDGDTFSGEQLNLMLQQREWREGFLAERMQDE
                     ILQEQILIETEGERIGQINALSVIEFPGHPRAFGEPSRISCVVHIGDGEFTDIERKAE
                     LGGNIHAKGMMIMQAFLMSELQLEQQIPFSASLTFEQSYSEVDGDSASMAELCALISA
                     LADVPVNQSIAITGSVDQFGRAQPVGGLNEKIEGFFAICQQRELTGKQGVIIPTANVR
                     HLSLHSELVKAVEEGKFTIWAVDDVTDALPLLLNLVWDGEGQTTLMQTIQERIAQASQ
                     QEGRHRFPWPLRWLNWFIPN"
     gene            20037..20489
                     /gene="matP"
                     /locus_tag="RN951_001580"
     CDS             20037..20489
                     /gene="matP"
                     /locus_tag="RN951_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ter protein MatP"
                     /protein_id="HDX2526595.1"
                     /translation="MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDVL
                     LSLENEPVLVNGWIDKHMNPELVNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFIVWQ
                     RLAGLAQRRGKTLSETIVQLIEDAENKEKYANKMSSLKQDLQALLGKE"
     gene            complement(20565..21605)
                     /gene="ompA"
                     /locus_tag="RN951_001581"
     CDS             complement(20565..21605)
                     /gene="ompA"
                     /locus_tag="RN951_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpA"
                     /protein_id="HDX2526596.1"
                     /translation="MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGF
                     INNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGSVKNGAYKAQGVQLTA
                     KLGYPITDDLDIYTRLGGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRL
                     EYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLK
                     SDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSER
                     RAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV
                     KGIKDVVTQPQA"
     gene            complement(21962..22471)
                     /gene="sulA"
                     /locus_tag="RN951_001582"
     CDS             complement(21962..22471)
                     /gene="sulA"
                     /locus_tag="RN951_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibitor SulA"
                     /protein_id="HDX2526597.1"
                     /translation="MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPM
                     MTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVES
                     MVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSG
                     LKIHSNLYH"
     gene            22690..23319
                     /gene="sxy"
                     /locus_tag="RN951_001583"
     CDS             22690..23319
                     /gene="sxy"
                     /locus_tag="RN951_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRP-S regulon transcriptional coactivator Sxy"
                     /protein_id="HDX2526598.1"
                     /translation="MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVS
                     DGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLNYYRVDESLWRNQLKLVRLSKYS
                     LDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
                     SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE"
     gene            complement(23282..25444)
                     /gene="yccS"
                     /locus_tag="RN951_001584"
     CDS             complement(23282..25444)
                     /gene="yccS"
                     /locus_tag="RN951_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309071.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01666 family membrane protein"
                     /protein_id="HDX2526599.1"
                     /translation="MAFMLSPLLKRYTWNSAWLYYARIFIALCGTTAFPWWLGDVKLT
                     IPLTLGMVAAALTDLDDRLAGRLRNLIITLFCFFIASASVELLFPWPWLFAIGLTLST
                     SGFILLGGLGQRYATIAFGALLIAIYTMLGTSLYEHWYQQPMYLLAGAVWYNVLTLIG
                     HLLFPVRPLQDNLARCYEQLARYLELKSRMFDPDIEDQSQAPLYDLALANGLLMATLN
                     QTKLSLLTRLRGDRGQRGTRRTLHYYFVAQDIHERASSSHIQYQTLREHFRHSDVLFR
                     FQRLMSMLGQACQQLSRCILLRQPYQHDPHFERAFTHIDAALERMRDNGAPADLLKTL
                     GFLLNNLRAIDAQLATIESEQAQALPHNNDENELADDSPHGLSDIWLRLSRHFTPESA
                     LFRHAVRMSLVLCFGYAIIQITGMHHGYWILLTSLFVCQPNYNATRHRLKLRIIGTLV
                     GIAIGIPVLWFVPSLEGQLVLLVITGVLFFAFRNVQYAHATMFITLLVLLCFNLLGEG
                     FEVALPRVIDTLIGCAIAWAAVSYIWPDWQFRNLPRMLERATEANCRYLDAILEQYHQ
                     GRDNRLAYRIARRDAHNRDAELASVVSNMSSEPNVTPQIREAAFRLLCLNHTFTSYIS
                     ALGAHREQLTNPEILAFLDDAVCYVDDALHHQPADEERVNEALASLKQRMQQLEPRAD
                     SKEPLVVQQVGLLIALLPEIGRLQRQITQVPQETPVSA"
     gene            complement(25454..25900)
                     /locus_tag="RN951_001585"
     CDS             complement(25454..25900)
                     /locus_tag="RN951_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HDX2526600.1"
                     /translation="MRTVLNILNFVLGGFATTLGWLLATLVSIVLIFTLPLTRSCWEI
                     TKLSLVPYGNEAIHVDELNPAGKNVLLNTGGTVLNIFWLIFFGWWLCLMHIATGIAQC
                     ISIIGIPVGIANFKIAAIALWPVGRRVVSVETAQAAREANARRRFE"
     gene            26023..28077
                     /gene="helD"
                     /locus_tag="RN951_001586"
     CDS             26023..28077
                     /gene="helD"
                     /locus_tag="RN951_001586"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase IV"
                     /protein_id="HDX2526601.1"
                     /translation="MELKATTLGKRLAQHPYDRAVILNAGIKVSGDRHEYLIPFNQLL
                     AIHCKRGLVWGELEFVLPDEKVVRLHGTEWGETQRFYHHLDAHWRRWSGEMSEIASGV
                     LRQQLDLIATRTGENKWLTREQTSGVQQQIRQALSALPLPVNRLEEFDNCREAWRKCQ
                     AWLKDIESARLQHNQAYTEAMLTEYADFFRQVESSPLNPAQARAVVNGEHSLLVLAGA
                     GSGKTSVLVARAGWLLARGEASPEQILLLAFGRKAAEEMDERIRERLHTEDITARTFH
                     ALALHIIQQGSKKVPIVSKLENDTAARHELFIAEWRKQCSEKKAQAKGWRQWLTEEMQ
                     WSVPEGNFWDDEKLQRRLASRLDRWVSLMRMHGGAQAEMIASAPEEIRDLFSKRIKLM
                     APLLKAWKGALKAENAVDFSGLIHQAIVILEKGRFISPWKHILVDEFQDISPQRAALL
                     AALRKQNSQTTLFAVGDDWQAIYRFSGAQMSLTTAFHENFGEGERCDLDTTYRFNSRI
                     GEVANRFIQQNPGQLKKPLNSLTNGDKKAVTLLDESQLDALLDKLSGYAKPEERILIL
                     ARYHHMRPASLEKAATRWPKLQIDFMTIHASKGQQADYVIIVGLQEGSDGFPAAARES
                     IMEEALLPPVEDFPDAEERRLMYVALTRARHRVWALFNKENPSPFVEILKNLDVPVAR
                     KP"
     gene            complement(28109..28567)
                     /gene="mgsA"
                     /locus_tag="RN951_001587"
     CDS             complement(28109..28567)
                     /gene="mgsA"
                     /locus_tag="RN951_001587"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415483.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HDX2526602.1"
                     /translation="MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYA
                     TGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDV
                     KALLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRLK"
     gene            complement(28663..29325)
                     /locus_tag="RN951_001588"
     CDS             complement(28663..29325)
                     /locus_tag="RN951_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2057 family protein"
                     /protein_id="HDX2526603.1"
                     /translation="MKTGIVTTLIALCLPVSVFATTLRLSTDVDLLVLDGKKVSSSLL
                     RGADSIELDNGPHQLVFRVEKTIHLSNSEERLYISPPLVVSFNTQLINQVNFRLPRLE
                     NEREANHFDAAPRLELLDGDATPIPVKLDILAITSTAKTIDYEVEVERYNKSAKRASL
                     PQFATMMADDSTLLSGVSELDAIPPQSQVLTEQRLKYWFKLADPQTRNTFLQWAEKQP
                     SS"
     gene            29498..29911
                     /locus_tag="RN951_001589"
     CDS             29498..29911
                     /locus_tag="RN951_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415485.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HDX2526604.1"
                     /translation="MKETDIAGILTSTHTIALVGASDKPDRPSYRVMKYLLDQGYHVI
                     PVSPKVAGKTLLGQKGYGTLADVPEKVDMVDVFRNSEAAWGVAQEAIAIGAKTLWMQL
                     GVINEQAAVLARDAGLNVVMDRCPAIEIPRLGLAK"
     gene            complement(29956..30273)
                     /gene="hspQ"
                     /locus_tag="RN951_001590"
     CDS             complement(29956..30273)
                     /gene="hspQ"
                     /locus_tag="RN951_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HspQ"
                     /protein_id="HDX2526605.1"
                     /translation="MIASKFGIGQQVRHSLLGYLGVVVDIDPVYSLSEPSPDELAVND
                     ELRAAPWYHVVMEDDNGLPVHTYLAEAQLSSELQDEHPEQPSMDELAQTIRKQLQAPR
                     LRN"
     gene            complement(30331..31521)
                     /gene="rlmI"
                     /locus_tag="RN951_001591"
     CDS             complement(30331..31521)
                     /gene="rlmI"
                     /locus_tag="RN951_001591"
                     /EC_number="2.1.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415487.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytosine(1962)-C(5))-methyltransferase
                     RlmI"
                     /protein_id="HDX2526606.1"
                     /translation="MSVRLVLAKGREKSLLRRHPWVFSGAVARMEGKASLGETIDIVD
                     HQGKWLARGAYSPASQIRARVWTFDPSESIDIAFFSRRLQQAQKWRDWLAQKDGLDSY
                     RLIAGESDGLPGITIDRFGNFLVLQLLSAGAEYQRAALISALQTLYPECSIYDRSDVA
                     VRKKEGMELTQGPVTGELPPALLPIEEHGMKLLVDIQHGHKTGYYLDQRDSRLATRRY
                     VENKRVLNCFSYTGGFAVSALMGGCSQVVSVDTSQEALDIARQNVELNKLDLSKAEFV
                     RDDVFKLLRTYRDRGEKFDVIVMDPPKFVENKSQLMGACRGYKDINMLAIQLLNEGGI
                     LLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEGLYLKGFA
                     CRVM"
     gene            31616..31894
                     /gene="yccX"
                     /locus_tag="RN951_001592"
     CDS             31616..31894
                     /gene="yccX"
                     /locus_tag="RN951_001592"
                     /EC_number="3.6.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HDX2526607.1"
                     /translation="MSKVCIIAWVYGRVQGVGFRYTTQYEAKRLGLTGYAKNLDDGSV
                     EVVACGEEGQVEKLMQWLKSGGPRSARVERVLSEPHHPSGELTDFRIR"
     gene            complement(31891..32220)
                     /gene="tusE"
                     /locus_tag="RN951_001593"
     CDS             complement(31891..32220)
                     /gene="tusE"
                     /locus_tag="RN951_001593"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309080.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusE"
                     /protein_id="HDX2526608.1"
                     /translation="MLIFEGKEIETDTEGYLKESSQWSEPLAVVIAENEGISLSPEHW
                     EVVRFVRDFYLEFNTSPAIRMLVKAMANKFGEEKGNSRYLYRLFPKGPAKQATKIAGL
                     PKPVKCI"
     gene            complement(32311..32970)
                     /gene="yccA"
                     /locus_tag="RN951_001594"
     CDS             complement(32311..32970)
                     /gene="yccA"
                     /locus_tag="RN951_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease modulator YccA"
                     /protein_id="HDX2526609.1"
                     /translation="MDRIVSSSHDRTSLLSTHKVLRNTYFLLSLTLAFSAITATASTV
                     LMLPSPGLILTLVGMYGLMFLTYKTANKPTGIISAFAFTGFLGYILGPILNTYLSAGM
                     GDVIAMALGGTALVFFCCSAYVLTTRKDMSFLGGMLMAGIVVVLIGMVANIFLQLPAL
                     HLAISAVFILISSGAILFETSNIIHGGETNYIRATVSLYVSLYNIFVSLLSILGFASR
                     D"
     gene            complement(33177..33264)
                     /locus_tag="RN951_001595"
     tRNA            complement(33177..33264)
                     /locus_tag="RN951_001595"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(33228..33230),aa:Ser,seq:tga)
     gene            33691..34809
                     /gene="hyaA"
                     /locus_tag="RN951_001596"
     CDS             33691..34809
                     /gene="hyaA"
                     /locus_tag="RN951_001596"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 small subunit"
                     /protein_id="HDX2526610.1"
                     /translation="MNNEETFYQAMRRQGVTRRSFLKYCSLAATSLGLGAGMAPKIAW
                     ALENKPRIPVVWIHGLECTCCTESFIRSAHPLAKDVILSLISLDYDDTLMAAAGTQAE
                     EVFEDIITQYNGKYILAVEGNPPLGEQGMFCISSGRPFIEKLKRAAAGASAIIAWGTC
                     ASWGCVQAARPNPTQATPIDKVITDKPIIKVPGCPPIPDVMSAIITYMVTFDRLPDVD
                     RMGRPLMFYGQRIHDKCYRRAHFDAGEFVQSWDDDAARKGYCLYKMGCKGPTTYNACS
                     STRWNDGVSFPIQSGHGCLGCAENGFWDRGSFYSRVVDIPQMGTHSTADTVGLTALGV
                     VAAAVGVHAVASAVDQRRRHNQQPTETEHQPGNEDKQA"
     gene            34806..36599
                     /gene="hyaB"
                     /locus_tag="RN951_001597"
     CDS             34806..36599
                     /gene="hyaB"
                     /locus_tag="RN951_001597"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase large subunit"
                     /protein_id="HDX2526611.1"
                     /translation="MSTQYETQGYTINNAGRRLVVDPITRIEGHMRCEVNINDQNVIT
                     NAVSCGTMFRGLEIILQGRDPRDAWAFVERICGVCTGVHALASVYAIEDAIGIKVPDN
                     ANIIRNIMLATLWCHDHLVHFYQLAGMDWIDVLDALKADPRKTSELAQSLSSWPKSSP
                     GYFFDVQNRLKKFVEGGQLGIFRNGYWGHPQYKLPPEANLMGFAHYLEALDFQREIVK
                     IHAVFGGKNPHPNWIVGGMPCAINIDESGAVGAVNMERLNLVQSIITRTADFINNVMI
                     PDALAIGQFNKPWSEIGTGLSDKCVLSYGAFPDIANDFGEKSLLMPGGAVINGDFNNV
                     LPVDLVDPQQVQEFVDHAWYRYPNDQVGRHPFDGITDPWYNPGDVKGSDTNIQQLNEQ
                     ERYSWIKAPRWRGNAMEVGPLARTLIAYHKGDAATVESVDRMMSALNLPLSGIQSTLG
                     RILCRAHEAQWAAGKLQYFFDKLMTNLKNGNLATASTEKWEPATWPTECRGVGFTEAP
                     RGALGHWAAIRDGKIDLYQCVVPTTWNASPRDPKGQIGAYEAALMNTKMAIPEQPLEI
                     LRTLHSFDPCLACSTHVLGDDGSELISVQVR"
     gene            36618..37325
                     /gene="hyaC"
                     /locus_tag="RN951_001598"
     CDS             36618..37325
                     /gene="hyaC"
                     /locus_tag="RN951_001598"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase b-type cytochrome subunit"
                     /protein_id="HDX2526612.1"
                     /translation="MQQKSDNVVSHYVFEAPVRIWHWLTVLCMAVLMVTGYFIGKPLP
                     SVSGEATYLFYMGYIRLIHFSAGMVFTVVLLMRIYWAFVGNRYSRELFIVPVWRKSWW
                     QGVWYEIRWYLFLAKRPSADIGHNPIAQAAMFGYFLMSVFMIITGFALYSEHSQYAIF
                     APFRYVVEFFYWTGGNSMDIHSWHRLGMWLIGAFVIGHVYMALREDIMSDDTVISTMV
                     NGYRSHKFGKISNKERS"
     gene            37322..37909
                     /locus_tag="RN951_001599"
     CDS             37322..37909
                     /locus_tag="RN951_001599"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 maturation protease"
                     /protein_id="HDX2526613.1"
                     /translation="MSEQRVVVMGLGNLLWADEGFGVRVAERLYAHYHWPEYVEIVDG
                     GTQGLNLLGYVESASHLLILDAIDYGLEPGTLRTYAGERIPAYLSAKKMSLHQNSFSE
                     VLALADIRGHLPAHIALVGLQPAMLDDYGGSLSELAREQLPAAEQAALAQLAAWGIVP
                     QPANESRCLNYDCLSMENYEGVRLRQYRMTQEEQG"
     gene            37906..38304
                     /gene="hyaE"
                     /locus_tag="RN951_001600"
     CDS             37906..38304
                     /gene="hyaE"
                     /locus_tag="RN951_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-1 operon protein HyaE"
                     /protein_id="HDX2526614.1"
                     /translation="MSNDTPFDALWQRMLARGWTPVSESRLDDWLTQAPDGVVLLSSD
                     PKRTPEVSDNPVMIGELLREFPDYTWQVAIADLEQSEAIGDRFGVFRFPATLVFTGGN
                     YRGVLNGIHPWAELINLMRGLVEPQQERVS"
     gene            38301..39158
                     /locus_tag="RN951_001601"
     CDS             38301..39158
                     /locus_tag="RN951_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase expression/formation protein"
                     /protein_id="HDX2526615.1"
                     /translation="MSETFFHLLGPGTQPNDDSFSMNPLPITCQVNDEPSMAALEQCA
                     HSPQVIALLNELQHQLSERQPPLGEVLAVDLLNLNADDRHFINTLLGEGEVSVRIQQA
                     DDSESEIQEAIFCGLWRVRRRRGEKLLEDKLEAGCAPLALWQAATQNLLPTDSLLPPP
                     IDGLMNGLPLAHELLAHVRNPDAQPHSINLTQLPISEADRLFLSRLCGPGNIQIRTIG
                     YGESYINATGLRHVWHLRCTDTLKGPLLESYEICPIPEVVLAAPEDLVDSAQRLSEVC
                     QWLAEAAPT"
     gene            39292..40836
                     /gene="appC"
                     /locus_tag="RN951_001602"
     CDS             39292..40836
                     /gene="appC"
                     /locus_tag="RN951_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit 1"
                     /protein_id="HDX2526616.1"
                     /translation="MWDVIDLSRWQFALTALYHFLFVPLTLGLIFLLAIMETIYVVTG
                     KTIYRDMTRFWGKLFGINFALGVATGLTMEFQFGTNWSFYSNYVGDIFGAPLAMEALM
                     AFFLESTFVGLFFFGWQRLNKYQHLLVTWLVAFGSNLSALWILNANGWMQYPTGAHFD
                     IDTLRMEMTSFSELVFNPVSQVKFVHTVMAGYVTGAMFIMAISAWYLLRGRERDVALR
                     SFAIGSVFGTLAIIGTLQLGDSSAYEVAQVQPVKLAAMEGEWQTEPAPAPFHVVAWPE
                     QDQERNAFALKIPALLGILATHSLDKPVPGLKNLMAETYPRLQRGRMAWLLMQEISQG
                     NREPHVLQAFRGLEGDLGYGMLLSRYAPDMNHVTAAQYQAAMRGAIPQVAPVFWSFRI
                     MVGCGSLLLLVMLIALVQTLRGKIDQHRWVLKMALWSLPLPWIAIEAGWFMTEFGRQP
                     WAIQDILPTYSAHSALTTGQLAFSLIMIVGLYTLFLIAEVYLMQKYARLGPSAMQSEQ
                     PTQQQG"
     gene            40848..41984
                     /gene="appB"
                     /locus_tag="RN951_001603"
     CDS             40848..41984
                     /gene="appB"
                     /locus_tag="RN951_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HDX2526617.1"
                     /translation="MFDYETLRFIWWLLIGVILVVFMISDGFDMGIGCLLPLVARNDD
                     ERRIVINSVGAHWEGNQVWLILAGGALFAAWPRVYAAAFSGFYVAMILVLCSLFFRPL
                     AFDYRGKIADARWRKMWDAGLVIGSLVPPVVFGIAFGNLLLGVPFAFTPQLRVEYLGS
                     FWQLLTPFPLLCGLLSLGMVILQGGVWLQLKTVGVIHLRSQLATKRAALLVMLCFLLA
                     GYWLWVGIDGFVLLAQDANGPSNPLMKLVAVLPGAWMNNFVESPVLWIFPLLGFFCPL
                     LTVMAIYRGRPGWGFLMASLMQFGVIFTAGITLFPFVMPSSVSPISSLTLWDSTSSQL
                     TLSIMLVIVLIFLPIVLLYTLWSYYKMWGRMTTETLRRNENELY"
     gene            41997..42089
                     /gene="cbdX"
                     /locus_tag="RN951_001604"
     CDS             41997..42089
                     /gene="cbdX"
                     /locus_tag="RN951_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit CbdX"
                     /protein_id="HDX2526618.1"
                     /translation="MWYLLWFVGILLMCSLSTLVLVWLDPRLKS"
     gene            42169..43467
                     /gene="appA"
                     /locus_tag="RN951_001605"
     CDS             42169..43467
                     /gene="appA"
                     /locus_tag="RN951_001605"
                     /EC_number="3.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acid phosphatase/4-phytase"
                     /protein_id="HDX2526619.1"
                     /translation="MKAILIPFLSLLIPLTPQSAFAQSEPELKLESVVIVSRHGVRAP
                     TKATQLMQDVTPDAWPTWPVKLGWLTPRGGELIAYLGHYQRQRLVADGLLAKKGCPQS
                     GQVAIIADVDERTRKTGEAFAAGLAPDCAITVHTQADTSSPDPLFNPLKTGVCQLDNA
                     NVTDAILSRAGGSIADFTGHRQTAFRELERVLNFPQSNLCLKREKQDESCSLTQALPS
                     ELKVSADNVSLTGAVSLASMLTEIFLLQQAQGMPEPGWGRITDSHQWNTLLSLHNAQF
                     YLLQRTPEVARSRATPLLDLIKTALTPHPPQKQAYGVTLPTSVLFIAGHDTNLANLGG
                     ALELNWTLPGQPDNTPPGGELVFERWRRLSDNSQWIQVSLVFQTLQQMRDKTPLSLNT
                     PPGEVKLTLAGCEERNAQGMCSLAGFTQIVNEARIPACSL"
     gene            complement(43582..45762)
                     /gene="etk"
                     /locus_tag="RN951_001606"
     CDS             complement(43582..45762)
                     /gene="etk"
                     /locus_tag="RN951_001606"
                     /EC_number="2.7.10.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HDX2526620.1"
                     /translation="MTTKNMNTPPGSTQENEIDLLRLVGELWDHRKFIISVTALFTLI
                     AVAYSLLSTPIYQADTLVQVEQKQGNAILSGLSDMIPNSSPESAPEIQLLQSRMILGK
                     TIAELNLRDIVEQKYFPIVGRGWARLTKEKPGELAISWMHIPQLNGQDQQLTLTVGEN
                     GHYTLEGEEFTVNGMVGQRLEKDGVALTIADIKAKPGTQFVLSQRTELEAINALQETF
                     TVSERSKESGMLELTMAGDDPQLITRILNSIANNYLQQNIARQAAQDSQSLEFLQRQL
                     PEVRSELDQAEEKLNVYRQQRDSVDLNLEAKAVLEQIVNVDNQLNELTFREAEISQLY
                     KKDHPTYRALLEKRQTLEQERKRLNKRVSAMPSTQQEVLRLSRDVEAGRAVYLQLLNR
                     QQELSISKSSAIGNVRIIDPAVTQPQPVKPKKALNVVLGFILGLFISVGAVLARAMLR
                     RGVEAPEQLEEHGISVYATIPMSEWLDKRTRLRKKNLFSNQQRHRTKNIPFLAVDNPA
                     DSAVEAVRALRTSLHFAMMETENNILMITGATPDSGKTFVSSTLAAVIAQSDQKVLFI
                     DADLRRGYSHNLFTVSNEHGLSEYLAGKDELNKVIQHFGKGGFDVITRGQVPPNPSEL
                     LMRDRMRQLLEWANDHYDLVIVDTPPMLAVSDAAVVGRSVGTSLLVARFGLNTAKEVS
                     LSMQRLEQAGVNIKGAILNGVIKRASTAYSYGYNYYGYSYSEKE"
     gene            complement(45782..46227)
                     /gene="etp"
                     /locus_tag="RN951_001607"
                     /gene_synonym="yccY"
                     /pseudo
     CDS             complement(45782..46227)
                     /gene="etp"
                     /locus_tag="RN951_001607"
                     /gene_synonym="yccY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309165.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine-phosphatase Etp"
     gene            complement(46215..47354)
                     /locus_tag="RN951_001608"
     CDS             complement(46215..47354)
                     /locus_tag="RN951_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein"
                     /protein_id="HDX2526621.1"
                     /translation="MKKNIFKFSVLTLAVLSLTACTLVPGQNLSTSNKDVIELPDNQY
                     DLDKMVNIYPVTPGLIDQLRAKPIMSQANPELEQQIANYEYRIGIGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNADGAIFYPYIGRLKVAGKTLTQVRNEITARLDSVIESPQ
                     VDVSVAAFRSQKAYVTGEVSKSGQQPITNIPLTIMDAINAAGGLTADADWRNVVLTQN
                     GVKTKVNLYALMQRGDLRQNKLLHPGDILFIPRNDDLKVFVMGEVGKQSTLKMDRSGM
                     TLAEALGNAEGMNQDVADATGIFVIRATQNKQNGKIANIYQLNAKDASAMILGTEFQL
                     EPYDIVYVTTAPLARWNRVISLLVPTISGVHDLTETSRWIQTWPN"
     gene            complement(47400..49496)
                     /locus_tag="RN951_001609"
     CDS             complement(47400..49496)
                     /locus_tag="RN951_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbH domain-containing protein"
                     /protein_id="HDX2526622.1"
                     /translation="MKKNSYLLSCLAIAVSSACHAEVLTYPDPLGSSQSDFGGTGLLQ
                     MPNARIAPEGEFSVNYRDNDQYRFYSTSVALFPWLEGTIRYTDVRTRKYSQWEDFSGD
                     QSYKDKSFDFKLRLWEEGYWLPQVAFGKRDIAGTGLFDGEYLVASKQAGPFDFTLGMA
                     WGYAGNAGNITNPFCRVSDKYCHRAESHDAGDISFSDIFRGPASIFGGIEYQTPWNPL
                     RLKLEYDGNNYQNDFAGKLPQASHFNVGAVYRAASWADLNLSYERGNTLMFGFTLRTN
                     FNDLRPALRDTPKPAYQPAPESEGLQYTTVANQLTALKYNAGFDAPEIQLRDKTLYMS
                     GQQYKYRDSREAVDRANRILVNNLPQGVEKISVTQKREHMAMVTTETDVASLRKQLAG
                     TAPGQSEPLQQQRVEAEDLSAFGRGYRIREDRFSYSFNPTLSQSLGGPEDFYMFQLGL
                     MSSARYWFTDHLLLDGGIFTNIYNNYDKFKSSLLPADSTLPRVRTHIRDYVRNDVYLN
                     NLQANYFADLGNGFYGQVYGGYLETMYAGVGSELLYRPLDACWALGVDVNYVKQRDWD
                     NMMRFTDYSTPTGFVTAYWNPPTLNGVLMKLSVGQYLAKDKGATIDVAKRFDSGVAVG
                     VWAAISNVSKDDYGEGGFSKGFYISIPFDLMTIGPNRNRAVVSWTPLTRDGGQMLSRK
                     YQLYPMTAEREVPVGQ"
     gene            complement(49496..50242)
                     /locus_tag="RN951_001610"
     CDS             complement(49496..50242)
                     /locus_tag="RN951_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule biosynthesis GfcC family protein"
                     /protein_id="HDX2526623.1"
                     /translation="MNKLQSYFIASVLYVMTPHAFAQGTVTIYLPGEQQTLSVGPVEN
                     VVQLVTQPQLRDRLWWPGALLTDSAAKAKALKDYQHVMAQLASWEAEADDDVAATIKS
                     VRQQLLNLNITGRLPVKLDPDFVRVDENSNPPLVGDYTLYTVQRPVTITLLGAVSGAG
                     QLPWQAGRSVTDYLQDHPRLAGADKNNVMVITPEGETVVAPVALWNKRHVEPPPGSQL
                     WLGFSAHVLPEKYADLNDQIVSVLTQRVPD"
     gene            complement(50239..50883)
                     /gene="gfcB"
                     /locus_tag="RN951_001611"
     CDS             complement(50239..50883)
                     /gene="gfcB"
                     /locus_tag="RN951_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein GfcB"
                     /protein_id="HDX2526624.1"
                     /translation="MRPLILSIFALFLAGCTHSQQSMVDTFRASLFDNQDITVADQQI
                     QALPYSTMYLRLNEGQRIFVVLGYIEQEQSKWLSQDNAMLVTHNGRLLKTVKLNNNLL
                     EVTNSGQDPLRNALAIKDGSRWTRDILWSEDNHFRSATLSSTFSFAGLETLNIAGRNV
                     LCNVWQEEVTSTRPEKQWQNTFWVDSATGQVRQSRQMLGAGVIPVEMTFLKPAP"
     gene            complement(50990..51295)
                     /locus_tag="RN951_001612"
     CDS             complement(50990..51295)
                     /locus_tag="RN951_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine-rich inner membrane protein GfcA"
                     /protein_id="HDX2526625.1"
                     /translation="MKHKLSAILMAFMLTTPAAFAAPEATNGTEATTGTTGTTTTTTG
                     ATTTATTTGGVAAGAVGTATVVGVATAVGVATLAVVAANDSGDGGSHNTSTTTSTTR"
BASE COUNT        12747 a        12694 c        13580 g        12484 t
ORIGIN      
        1 gttctggagg ggatattcat attttttaag agtgactatt tatgaaaact tgcataacaa
       61 agggaattgt gaccgtaagt ttaacggcaa tattactcag ctgctcatcc gcatgggcgg
      121 caggtaaagg cgggattgga cttgcagcaa cacgtcttgt ttattcagaa ggtgaagagc
      181 aaatttcact gggtgtacgt aacaccagtc cggatgttcc ttatcttatt cagtcatggg
      241 tgatgacccc agataataaa aaatcagcag actttattat tacaccaccg ctatttgtgc
      301 tgaatccggc aaatgagaat ctgttacgca ttatgtacat tggagcgccg ttggcgaaag
      361 acagagaaac ccttttcttc actagcgtac gggcagtccc ttcaacaacg aagcggaaag
      421 agggaaatac cctgaagatt gccacacaaa gcgtcatcaa acttttctgg cgaccaaaag
      481 gtttagcgta tcccttaggc gaggctccgg cgaaactgcg ttgcacttcg tcagctgaca
      541 tggttacggt cagtaaccca acaccttatt tcattaccct gacagacctg aaaataggtg
      601 gaaaagtagt taaaaatcaa atgatttccc cctttgataa ataccaattt tctctgccaa
      661 agggggccaa aaatagcagc gtaacgtatc gaaccatcaa tgactacggg gcggaaacgc
      721 cgcaactcaa ctgtaaatcg taagccgtct tcagttaaga gagcgagatg tatagaactc
      781 atcgacaaca cagcctgtta agctctggtg gagtgccatc gtttattggt gggctggtgg
      841 tgtttgtgtc ggcagcgttc aatgcacaag ctgaaacctg gttcgatcct gcttttttca
      901 aagatgatcc ctcaatggtg gccgatttgt ctcgtttcga aaaaggacaa aaaataacgc
      961 caggggttta tcgtgtcgat attgttctga atcagacaat tgtagatacg cgcaacgtca
     1021 attttgttga gataacgcca gagaagggga ttgccgcctg tttgacgact gaaagcctgg
     1081 atgcaatggg tgttaatact gatgcgtttc cggcttttaa acaactggac aaacaagcgt
     1141 gtgtgccatt ggcggagatt attccggatg ccagcgtaac gtttaatgtg aataaactcc
     1201 gtctggaaat ttcagtaccg caaatcgcca tcaaaagtaa tgcccgtggt tatgtccccc
     1261 ctgaacgttg ggatgaaggg atcaacgcgc tattactggg atattcgttt agcggggcta
     1321 acagtattca tagcagcgca gacagtgatt ctggcgacag ctattttctg aatttaaaca
     1381 gtggcgttaa tttaggccca tggagattgc gcaacaattc aacatggagt cgtagtagtg
     1441 gccaaaccgc agaatggaag aatctcagca gctatttgca acgggcggtt attcctctga
     1501 aaggcgaact gaccgtaggt gatgattata ctgcaggcga ttttttcgat agtgtcagct
     1561 ttcgtggtgt gcagctggcg tcagatgaca acatgctgcc agacagcctg aaagggtttg
     1621 cgcctgtggt gcgtggtatc gccaaaagca atgcccagat aacgattaag caaaatggtt
     1681 acaccattta ccaaacttat gtatcgcctg gtgcttttga aattagtgat ctctattcca
     1741 cgtcgtcgag cggtgatttg ttagttgaaa tcaaagaagc ggacggcagc gtcaatagct
     1801 acagcgtacc gttctccagt gtgccattac tccagcgtca ggggcgaatc aaatacgcgg
     1861 tgacactggc gaaatacaga accaatagta atgaacagca ggagagcaaa tttgcccagg
     1921 ccacgttgca gtggggcgga ccgtggggaa cgacctggta tggtggtgga caatatgctg
     1981 aatattaccg tgccgccatg tttggtctgg gatttaacct cggcgatttc ggagcaattt
     2041 cgttcgatgc gacccaggcg aagagtacgc tagcagatca aagcgaacat aaaggtcagt
     2101 catatcgttt tctgtatgcc aaaacgctca accacttggg cactaacttt caattgatgg
     2161 gctatcgcta ttcgacgtcg ggtttctaca ccctttccga caccatgtat aaacatatgg
     2221 atggctacga atttaatgac ggtgatgatg aagatacgcc gatgtggtcg cgttattaca
     2281 atttgtttta caccaaacgt ggcaaactgc aggtcaatat ctcccagcaa ttaggcgagt
     2341 acggttcgtt ttatttaagt ggtagccagc aaacttactg gcatacggat caacaggatc
     2401 ggctattaca gtttggctac aacacgcaaa ttaaagatct ttcgctgggg atttcctgga
     2461 actacagtaa gtcccgtggt caacctgatg ctgatcaggt gtttgctcta aatttttccc
     2521 tgccgctcaa tctgttgctc cccagaagta atgatagcta taccaggaaa aaaaattacg
     2581 cctggatgac ctctaacacc agtatcgata acgaagggca cactacacaa aacctgggtt
     2641 taacggagac attactcgat gacggtaacc tgagctacag cgtgcaacag ggatataaca
     2701 gcgaggggaa aacggctaat ggtagcgcca gcatggatta caaaggggcg tttgcggatg
     2761 cccgagtggg ctacaactac agcgataacg gcagtcaaca acaactgaac tacgctcttt
     2821 caggcagttt agttgcccat tcacagggca ttaccctggg gcaatcgctg ggggaaacta
     2881 acgttctgat tgcagcacca ggcgcagaga atactcgtgt ggcgaacagc accgggctga
     2941 aaactgactg gcgcggatat accgttgttc cttatgccac ttcttatcgg gaaaatcgaa
     3001 tcgcacttga tgcggcgtcg ttaaaacgta acgtggatct tgaaaatgca gtagtcaacg
     3061 tggttcccac caaaggggcg ttggttctgg cggagttcaa tgcccatgcg ggtgcaaggg
     3121 tattaatgaa aacatcaaag cagggtatac cgctgcgttt tggcgcgata gcgacgctgg
     3181 acggcgtaca ggctaatagc ggcataattg atgatgatgg ctcgctctat atggcgggtt
     3241 taccggcgaa gggaacaata agcgtgcgct ggggcgaagc tcccgatcaa atttgtcata
     3301 tcaattacga gcttaccgaa caacaaatta actctgcgat tacgcgaatg gatgccatat
     3361 gcagataatc tttggagaaa aatgcgtgtc attactacga ctattttttg ccgccgtctt
     3421 aatgctatgg tgcgctcaaa ccgctgctta tagcgggcag tgtcatacta ctcaggggaa
     3481 tccgtatatt ggcgtcaatt ttggcgttaa aaccctggag gaagaagcaa atacggcagg
     3541 ggtagttaaa gacaaatttt atcagtggaa cgaatcgaat gattattatg tttcctgtga
     3601 ttgcgataaa gacaatgtca gaagtggccg atgggcattc gccgcggatt caccgttagt
     3661 ctatttaggc gacaactggt acaaaattaa tgactatctt gccgccaaag ttttattgca
     3721 ggttaaaggc agttctccta ctgcggttcc tttcgaaaac gtgggcacag ggggggatac
     3781 ccgatggcat atttgcgacc ctggcggtca acgtttaggt gggcaggggg caagcggtaa
     3841 tagcggtagc ttttccctga aaatattgca gccgttcgtt ggctcggtcg tcattcctcc
     3901 tatggcgctg gcgcgattat atgaatgcta caacataccc gcaggtgatt cctgcacgac
     3961 tacaggtaca ccggttttag tgtattacct gtctggtacg atcaattcac ttggctcatg
     4021 ttccgtcaat gccggagaga caattgaagt tgatttaggt gatgtcttcg ctgccaattt
     4081 ccgtgttgta gggcataaac ctcttggggc cagaacggca gaacttgcaa ttccagtcag
     4141 gtgtaacacg ggaaacgcgg gattagttaa tgtcaacctg agtctgacgg caaccacaga
     4201 ccccagctat ccccaggcga ttaagacgtc acgtcctggc gtgggcgtgg tggtgaccga
     4261 tagccagaac aacattattt cccctgctgg tggaacatta ccgctctcta ttcctgatga
     4321 tgcagacagt atcgcgcgaa tgaatgtcta tccagtcagc acgacaggtg taccaccaga
     4381 aaccgggcga tttgaagcca cggcaacggt gagaataaat tttgattaac gcgtgaacgt
     4441 atgaagaaaa aaacgatatt tcagtgcgtt atcttgttct ttagcattct taacatccat
     4501 gtcgggatgg ctgggcctga acaagttagt atgcatattt atgggaatgt ggtcgatcag
     4561 ggctgtgatg tcgccaccaa aagtgcatta caaaatattc atattggtga ttttaatatc
     4621 agtgattttc aggccgcgaa taccgtaagc actgctgctg atttgaatat cgatatcacc
     4681 ggttgtgccg ctggtattac tggcgcggac gtccttttta gcggcgaggc tgacaccctt
     4741 gcgccgacac tgctcaaact aactgacaca ggcggaagcg gtggtatggc aacggggatt
     4801 gccgtgcaaa ttcttgatgc gcaaagtcag caagaaatcc cgctcaatca ggtccagcct
     4861 cttacgccct taaaagccgg ggataacaca ctcaaatatc aacttcgtta taagtccaca
     4921 aaggcgggag caacgggcgg taatgcgacg gcggttctct attttgatct ggtttaccag
     4981 tgaaggagtg atgttgaaac ggataatctg gattctgttc ttattgggat taacgtgggg
     5041 ctgtgagcta tttgcccatg atggcacggt caacattagc ggatcgtttc gccgtaatac
     5101 atgcgtgctg gcacaggata gcaagcaaat caatgtgcag ttaggcgatg tctcgctgac
     5161 acgtttttct catgggaatt atggcccgga gaaatctttc atcattaatt tgcaggattg
     5221 cggaacagat gtcagcacgg ttgacgtcac cttttcagga acccccgacg gagtgcagag
     5281 cgaaatgttg tccattgaaa gtggtacgga tgcagccagc gggctggcaa ttgcgattct
     5341 ggatgatgcg aagatattga ttccgcttaa ccaggcgagt aaagactaca gcctacatag
     5401 cggtaaggtg ccattaactt tttatgcgca attgcgacct gtcaatagcg atgtgcagtc
     5461 gggtaaagtg aatgccagcg cgacatttgt acttcattat gactaatacg tggaacagat
     5521 tggcgctctt gattttcgcc gttttatcgc tgctggtggc gggtgaattg caggcaggag
     5581 tggtggtcgg cggaacgcga tttatctttc cggcagacag agaatcgata tctattttac
     5641 tgactaatac cagtcaggaa tcctggctta ttaacagtaa aatcaaccgc ccaacgcgtt
     5701 gggccggggg ggaagcgtcg acagtgccag caccattact ggccgctccg ccacttattc
     5761 tcctgaagcc cggtacgaca ggcacgttgc gcttgctgag aacggaaagc gacatcttgc
     5821 ctgtggatcg cgaaacgcta tttgagttaa gcattgccag cgtgccatcc ggcaaagttg
     5881 aaaatcagag cgtaaaagtg gcgatgcgct cggtatttaa actgttctgg cgacccgaag
     5941 gtttgccggg cgacccgctg gaagcttatc aacaattacg ctggacacgg aattcgcagg
     6001 gtgtacaact cactaaccca acgccttatt acattaacct gattcaggtg agtgtaaatg
     6061 gtaaagcgtt aagtaatatg ggagttgtgc cgcctaaaag ccagcgtcag acaagctggt
     6121 gtcaggcaat cgcaccgtgt catgtcgcct ggcgggcgat aaatgattac ggcgggttga
     6181 gtgcaaagaa ggagcaaaat ctgccctgaa acaggttcgg aaaacgtttg cgtttttttt
     6241 gccgcaggtc aattcccttt tggtccgaac tcgcacataa tacgcccccg gtttgcacac
     6301 cgggaatcca ggagagttca tgtactaccc cttcgttcgt aaagcccttt tccagctcga
     6361 tccagagcgc gctcatgagt ttacttttca gcaattacgc cgtattacag gaacgccgtt
     6421 tgaagcactg gtgcggcaga aagtgcctgc gaaacctgtt aactgcatgg gcctgacgtt
     6481 taaaaatccg cttggtctgg cagccggtct tgataaagac ggggagtgca ttgacgcgtt
     6541 aggcgcgatg ggatttggat cgatcgagat cggtaccgtc acgccacgtc cacagccagg
     6601 taatgacaag ccgcgtctct ttcgtctggt agatgccgaa ggtttgatca accgtatggg
     6661 ctttaataat cttggcgttg ataacctcgt agagaacgta aaaaaggccc attatgacgg
     6721 cgtcctgggt attaacatcg gcaaaaataa agatacgcca gtggagcagg gcaaagatga
     6781 ctatctgatt tgtatggaaa aaatctatgc ctatgcggga tatatcgcca tcaatatttc
     6841 atcgccgaat accccaggat tacgcacgct gcaatatggt gaagcgctgg atgatctctt
     6901 aaccgcgatt aaaaataagc aaaatgattt gcaagcgatg caccataaat atgtgccgat
     6961 cgcagtgaag atcgcgccgg atctttctga agaagaattg atccaggttg ccgatagttt
     7021 agttcgccat aatattgatg gcgttattgc aaccaatacc acactcgatc gttctcttgt
     7081 tcagggaatg aaaaattgcg atcaaaccgg tggcttaagt ggtcgtccgc ttcagttaaa
     7141 aagcaccgaa attattcgcc gcttgtcact ggaattaaac ggtcgcttac cgatcatcgg
     7201 tgttggcggc atcgactcgg ttatcgctgc gcgtgaaaag attgctgcgg gtgcctcact
     7261 ggtgcaaatt tattctggtt ttatttttaa aggtccgccg ctgattaaag aaatcgttac
     7321 ccatatctaa ttatttcttc gaattcctct ttataagata atcagggctt tattttcagc
     7381 cctggttgtt ttatattcat cgctgttgct tatttagaca ttttgtactt ttattgttga
     7441 ggttattaag cgaagcgaca atggattgtg ttgctgcggt tttatagggt aggggagagg
     7501 cagatgcgaa ttaaaccaga cgataactgg cgttggtatt acgatgaaga gcacgatcga
     7561 atgatgctcg atttagccaa tggtatgcta tttcgctcac gttttgcgcg caagatgttg
     7621 actccagatg ccttttctcc cgcaggcttt tgcgttgacg acgccgcgct ctatttctct
     7681 tttgaagaaa agtgccgcga ttttaattta tctaaagaac aaaaagccga actggtgctg
     7741 aatgcactgg tagcaattcg ctatctcaaa ccgcaaatgc cgaaaagctg gcattttgtt
     7801 tcccatggtg aaatgtgggt gcccatgccg ggcgatgcgg cctgcgtttg gttgagcgat
     7861 actcacgagc aggtcaattt gctggtcgtt gaatctggcg aaaatgccgc actatgcctg
     7921 ctggcacaac cctgcgttgt tattgcgggt cgcgcgatgc agttgggcga cgccattaaa
     7981 atcatgaacg acaggctgaa accgcaggtt aatgttgaca gcttcagcct cgaacaggca
     8041 gtctaacgcg ccaacttaag tgcagtcttc ggtacacagc tacagcaaag aatggtgcca
     8101 tcatcgccca ttgctgattt tttcagcggc gtgacttcgc cttctaaaag ctgaacacgg
     8161 caacttccac aaatgcccgc gcggcaagaa taagggatac gaattccctg attttctaat
     8221 tgctccagca acacctgttg gttatttcca cgaaatgcct gtccctgcca gtcaatatct
     8281 acatttgcgt ccggttgttg cgtgatgttg gcggtatcat cagcggcagc tgcgccgtaa
     8341 atttttgccg gagccgttgc cagaatttcc acctcatcgc caacgcgaat cacgccgcta
     8401 ttacgggcaa ttaaattctg accaaaatcg acatcgccgt tatcctgggc agtgcggaaa
     8461 gattgcaatg tttttaatgg ttcgcctgcc ggatgttttt gccctttttc tgggctgacg
     8521 gtggtgaaaa tacagcggct acaaggttta accacatcaa acaccacatc accaatgcga
     8581 atcactttcc agcgatcttc ttcccaggct gacgcgccgg aaaccaccag attggggcgg
     8641 aattgctcca tttttacact ggccggacaa cgttgttgga gatcacgtaa cgaggcttcg
     8701 ttagcaagaa ggtaaggata gccatcagca aatgacagag gtacagtgtt gtggcgtttc
     8761 acgcgccggg tcatttgtgg ccccacccag cgtaattgca cttcgcggga gaaaaattca
     8821 cttagccatt tgttgatcgc gtctggcgca attcgcgcgg taaaatgtgt gccccaaact
     8881 tcggttggtg cgtcttgtgt ggcgaaatca gcaaaacgaa catatgcgct actgccatct
     8941 ggtgcggtga gatgcaagcc atcatgcaca ggtgaaggag taaaccgtac catctgggga
     9001 aactggcgag cggtaataaa cgtaccgtca ggttccgtga tcataaagat gcgatcgaag
     9061 gccagaccac tgacatctgc cagagcatgt gtaagaccaa tgccgcgcat cgatttaaca
     9121 ggatgaataa aaagccggat taatgtcgcc acggtgcggt cctcaaatga aaataagccc
     9181 tcaactttat gacatgacgc gcttattagc tataatgcgc aacaattttc ttagcgcctg
     9241 tcccattagg ctattttatt tgtcagtttg gccctgggtt atgctcgaaa tcctcacgta
     9301 cttgtgtacg ctccggtttc tccgcgctgt ccatgtccag actgactgca acaattacgc
     9361 ctactgcggt aggctcttag agtaaaagtg acgatatgaa ttctctgttt gccagtacgg
     9421 cccgtgggct ggaagagctg ttaaaaactg aactggaaaa cctgggggcc gttgaatgcc
     9481 aggtggttca gggtggggtc catttcaagg gcgacacacg gcttgtttac cagagcctga
     9541 tgtggagccg cctggcctcg cgtattatgt tgccgctggg cgagtgtaag gtttacagcg
     9601 atttagacct ctatctcggt gttcaggcga tcaactggac agagatgttt aatcctggcg
     9661 cgaccttcgc tgtccacttc agtggtttga atgacaccat ccgcaacagt cagtacggcg
     9721 cgatgaaagt gaaagacgcg atcgtcgatg ctttcacgcg gaaaaatctg ccgcgtccaa
     9781 atgttgatcg cgatgcgccg gatatccgcg ttaacgtctg gctgcataaa gaaaccgcca
     9841 gtatcgctct tgatctgagt ggtgatggtt tacatctgcg tggctatcgc gatcgtgctg
     9901 gtattgcgcc gatcaaagaa accctggcag ccgctattgt gatgcgatcc ggctggcagc
     9961 caggaacacc gctgctcgat ccgatgtgtg gttccggtac gttgctgatt gaagcagcga
    10021 tgctggcgac cgatcgcgca ccaggcttgc accgtgggcg ttggggcttt agcggctggg
    10081 cgcagcatga tgaagctatc tggcaggaag tgaaagcgga agcgcaaact cgcgcccgta
    10141 aaggcctggc tgagtatagc tctcattttt acggttcgga cagcgacgca cgggtgattc
    10201 aacgtgcacg cactaacgcc cgtcttgcgg ggattggtga actgatcacc tttgaggtga
    10261 aagatgtcgc gcaactgacc aatccgctgc cgaaagggcc gtacggcaca gtgttgagca
    10321 acccgccata cggggaacgt ctggacagcg aaccggcgct gattgcgctg catagcctgc
    10381 tgggtcggat catgaaaaac cagtttggtg gctggaatct ctctttgttt agtgcctcgc
    10441 cggatctgct aagctgcttg cagctgcgtg cagacaaaca gtacaaggcg aaaaacggcc
    10501 cgctggactg cgtacagaaa aattaccacg ttgccgaaag cactccagac agcaaaccgg
    10561 cgatggtagc ggaagactac accaaccgcc tgcgtaagaa cctcaaaaaa ttcgagaagt
    10621 gggctcgcca ggaagggatt gaatgttacc gcctgtatga cgccgatctg ccagaatata
    10681 acgttgccgt tgaccgttat gccgactggg tggtggtgca ggagtatgcg ccgccaaaaa
    10741 ctattgatgc tcacaaagcg cgtcagcgtc tgttcgatat tatcgctgca accatttcgg
    10801 tactggggat tgcgccaaac aaactggtgc tgaaaacccg tgaacgccag aagggcaaaa
    10861 accaatacca gaaactgggc gagaagggcg agtttcttga agttaccgaa tataacgctc
    10921 acttgtgggt gaacctgacg gattatctcg atactggtct gttcctcgat caccgcatcg
    10981 cccgtcgtat gctcggtcag atgagcaaag gcaaagattt cctcaacctg ttctcttata
    11041 ccggcagcgc caccgtgcat gcgggattag gcggtgcacg cagcaccacc accgtggata
    11101 tgtcgcgtac ttatctggaa tgggcagaac gcaacctgcg tctgaatggc ctgaccgggc
    11161 gtgcgcatcg cctgattcag gccgattgcc tggcgtggct gcgtgaggca aatgaacagt
    11221 tcgatctgat ctttatcgat ccgccaacct tctctaactc aaaacgaatg gaagatgcgt
    11281 ttgatgttca gcgcgatcat ctggcgctga tgaaagattt gaaacgtctg ctgcgtgcag
    11341 gtgggacgat catgttctcg aacaacaaac gtggcttccg tatggatctc gacggcctgg
    11401 caaaactggg actgaaagca caagaaatta cgcaaaaaac gctctcccag gatttcgccc
    11461 gtaaccgcca gatccacaac tgctggctga ttaccgcagc ctgaaaggaa tagtaatgtc
    11521 attaatcagt atgcatggcg catggctgtc gttcagcgac gcgccgcttc tcgataacgc
    11581 agaactgcat atcgaagata acgaacgtgt ttgtctggtg ggccgcaacg gcgcaggcaa
    11641 atcgacgtta atgaaaatcc tcaaccgtga acaagggctg gatgacggtc gcattattta
    11701 cgagcaagat ttgattgtag cgcgtctgca acaggatccg ccgcgtaacg ttgagggtag
    11761 cgtttatgat ttcgttgccg aaggcattga agaacaagcg gaatatctga aacgctatca
    11821 cgatatttcg cgcctggtga tgaacgaccc gagcgagaaa aatctcaacg aactggcgaa
    11881 ggttcaggaa cagctggatc accacaacct gtggcagctg gaaaaccgca tcaacgaagt
    11941 gctggcgcaa ctggggttag atcctaacgt tgcgctgtcg tcgctttccg gcggctggtt
    12001 gcgtaaagcg gcattaggac gcgcgctggt gagtaatccg cgcgtgctgt tgcttgatga
    12061 accgacaaac cacctggata ttgaaaccat cgactggctg gaagggtttt tgaaaacttt
    12121 caacgggacg attattttca tctcccacga ccgttcgttt atccgcaata tggcgacgcg
    12181 cattgttgat ctcgatcgcg gcaagctggt gacctatcca gggaattacg accagtacct
    12241 gctggaaaaa gaagaagccc tgcgcgtgga agaattacaa aatgccgagt tcgatcgcaa
    12301 actggcgcag gaagaggtgt ggatccgcca ggggatcaaa gcacgccgta cccgtaatga
    12361 aggccgcgta cgcgccctga aagcgatgcg tcgcgaacgt ggtgaacgtc gcgaagtgat
    12421 gggtaccgca aagatgcagg tggaagaggc cagccgctcc ggtaaaatcg ttttcgaaat
    12481 ggaagacgtt tgctaccagg ttaacggtaa gcaactggtg aaagattttt ctgcccaggt
    12541 tctacgtggc gacaaaattg ccctgattgg tccgaatggg tgcggcaaaa ccacgctgct
    12601 aaaactgatg ctcggtcagc ttcaagcgga cagcgggcgt attcacgttg gcaccaaact
    12661 ggaagtggct tatttcgatc agcaccgcgc ggaactggat cccgataaaa cggtgatgga
    12721 taaccttgcc gaaggtaagc aagaggtgat ggttaacggc aagccacgcc acgtattggg
    12781 ctatttgcag gactttctgt tccatccgaa acgggcgatg acgccggtac gtgcgctttc
    12841 tggcggtgag cggaaccgct tgctgctggc gcgtttgttc ctcaaaccaa gcaacttatt
    12901 gattcttgac gaaccgacca acgatcttga tgtcgaaacg ctggaactgc tggaagaact
    12961 gatcgacagc tatcagggca cggtattgct ggttagccac gatcgtcagt ttgtcgataa
    13021 caccgttaca gaatgttgga tcttcgaagg cggcggtaaa attggtcgtt atgtcggcgg
    13081 ttatcatgat gcccgtggtc agcaagagca gtatgtggcg ctcaaacagc ctgcggtgaa
    13141 aaaaaccgaa gaagccgccg cggcaaaagc agaaactgta aaacgcagca gtagcaaact
    13201 aagctataaa ttgcagcgcg aactggagca gctaccgcaa ttgctcgaag atctggaggc
    13261 gaagctggaa gccctacaga cgcaagtggc ggatgcttcc ttcttcagtc agccgcatga
    13321 gcagacgcaa aaagtgcttg ctgatatggc tgctgcagag caggagctgg agcaagcctt
    13381 tgaacgctgg gagtatcttg aagcgttaaa aaatggtggc tgatcgcaaa atagtcgatt
    13441 taaacagaga cagctgacaa cggtaaaatt gcctgatgaa ctgggtttat caggcatgaa
    13501 aaccaacact ttgttagtca tctgtaaaat agcgcatcat taaggagtac caatgtgcga
    13561 acatcatcat gccgcgaagc acatcctgtg ctcgcagtgt gacatgctgg tggcgttacc
    13621 gcgccttgag catggtcaga aagcggcatg tccccggtgt ggcacaacgt taaccgtggc
    13681 gtgggatgcc cctcggcagc gtcccaccgc ctatgcgttg gctgcactgt tcatgctgtt
    13741 gctgtccaac ttgtttcctt ttgtgaatat gaacgttgca ggagttacca gtgaaattac
    13801 attactggaa attcccggcg tgcttttttc tgaggactac gccagcctcg gcaccttttt
    13861 cctgttgttt gtgcaactgg ttcccgcgtt ttgtctgata accattctgt tactggtgaa
    13921 tcgcgcggaa ttaccggtcc gtttaaaaga gcaactggca cgggtgcttt ttcaactcaa
    13981 aacctgggga atggcggaga ttttcctcgc gggtgtgctg gtcagtttcg ttaaactgat
    14041 ggcttacggc agcattgggg taggcagcag ctttctcccc tggtgtttat tttgtgtcct
    14101 gcaactgcgc gcttttcagt gcgttgatcg tcgctggtta tgggacgaca tcgccccgat
    14161 gccagaactg cgccagccgc taaaaccagg cgtcacgggg atacgtcagg ggctgcgttc
    14221 gtgctcctgt tgtacggcaa tccttcctgc tgatgaaccc gtgtgcccgc gttgtagtac
    14281 caaagggtac gttcggcgta gaaacagcct gcagtggaca ctcgcgctgc ttgtaacgtc
    14341 catcatgctg tatcttccgg ctaatatttt gcccatcatg gtgacggatt tattaggctc
    14401 gaagatgccg tcgacgattc tcgctggggt cattctgtta tggagcgaag gctcttatcc
    14461 cgtcgctgcg gtgatctttc tggccagtat tatggtgcca acgttaaaga tgatcgccat
    14521 cgcgtggctg tgttgggatg ccaaagggca tggcaagcgc gacagtgaaa gaatgcattt
    14581 gatttatgaa gttgttgagt ttgtaggccg ctggtcgatg attgacgttt tcgttatcgc
    14641 ggtgctctcg gcgctggtgc gtatgggagg tttaatgagt atttatccgg caatgggtgc
    14701 attaatgttt gctttagtcg tcataatgac aatgttttct gctatgacgt ttgacccgcg
    14761 tttgtcgtgg gatcgtcaac ctgaatcaga gcatgaggag tcctgacagt atggaatcta
    14821 ataatgggga agccaaaatc cagaaagtga agaactggtc tcccgtgtgg atatttccta
    14881 tcgtcacggc gctcattggg gcctgggttc ttttttatca ttacagccat cagggaccgg
    14941 aagtgaccct gatcaccgcg aatgcggaag gaattgaagg tggcaaaacc accattaaaa
    15001 gccgtagcgt tgacgtcggc gtggttgaaa gcgccacact ggctgatgat ttgacgcacg
    15061 ttgaaatcaa agcgcggctg aattccggta tggaaaaatt gctgcataaa gacaccgtct
    15121 tttgggtggt gaaaccgcag attggtcgcg aagggattag cggcctggga acgctgctgt
    15181 ctggagttta tatcgaactg cagccaggcg cgaaaggcag caaaatggat aaatacgatt
    15241 tgctggactc gccaccgttg gccccgcctg atgcgaaagg tatccgtgtg attctcgata
    15301 gcaaaaaagc cgggcagctc tcgccaggag atccggtgct gttccgtggc tatcgggtag
    15361 gttcggttga aaccagcacc ttcgatacac aaaaacgcaa tatcagctat caactgttca
    15421 tcaatgcacc ttatgaccga ctggtgacca acaatgttcg cttctggaaa gatagtggca
    15481 ttgcggttga tctgacgtca gcagggatgc gtgtggagat gggctcattg acaacgctgc
    15541 tgagtggcgg tgtcagcttt gatgtgccgg aaggtctgga tttagggcag ccagtggcac
    15601 cgaaaacagc tttcgttttg tatgatgatc agaagagcat tcaggattcg ttgtacaccg
    15661 atcacattga ttatctgatg ttctttaaag attcggtacg cggtctgcaa ccgggagctc
    15721 cggtagagtt ccggggtatt cgcctgggta ccgtaagcaa agtgccattc tttgcgccga
    15781 atatgcgtca gacatttaac gatgattacc gtattccggt actgattcgt atcgagccag
    15841 agcggctgaa aatgcagctt ggcgaaaatg cggatgttgt tgagcacctt ggcgaattgt
    15901 tgaaacgtgg tttacgcgga tcgctgaaaa ccggaaacct ggtcactggt gcactgtatg
    15961 ttgatctcga tttctatcca aatacgcctg caataaccgg tattcgtgaa tttaatggtt
    16021 atcagattat cccgaccgtt agcggcggcc tggcgcaaat ccagcaacga ctgatggaag
    16081 cgttggataa gatcaacaaa ctgccattga atccgatgat tgaacaggca accagtacgc
    16141 tttctgaaag tcagcgcaca atgaaaaacc tgcaaacgac gctggatagc atgaacaaga
    16201 tcctcgctag ccagtcgatg cagcagttgc cgacggatat gcagtcaacg ttgcgtgaat
    16261 tgaatcgcag catgcagggc ttccagcctg gctccgcagc ctacaacaag atggtggcgg
    16321 atatgcagcg ccttgatcag gtgttgcgag aactgcaacc ggtgctgaaa acgctcaatg
    16381 agaagagtaa cgcgctggta tttgaagcga aggacaaaaa agatccagag ccgaagaggg
    16441 cgaaacaatg aaaaagtggc tagtgacgat tgcagcactg tggctggccg gatgcagctc
    16501 cggcgaaatt aataaaaact attaccagtt acctgtggtg cagagcggta cacaaagtac
    16561 cgccagccag ggcaatcgtc tgttatgggt agagcaggtc actgttcctg actatctggc
    16621 ggggaatggt gtggtttatc aaaccagtga tgtgaagtat gtgattgcca acaacaactt
    16681 gtgggccagc ccgttggatc aacagttgcg caacaccctg gttgccaacc tgagtacgca
    16741 actgcccggc tgggtggttg cctcccagcc tctgggaagc gcccaggaca cgctcaatgt
    16801 taccgtaacg gagtttaacg gtcgctatga tggcaaggtc attgtcagtg gtgagtggct
    16861 gttgaaccac cagggacaac tgatcaaacg tccgttccgt ctggaaggag tgcaaactca
    16921 ggatggttac gatgagatgg ttaaagtgct ggccggtgtc tggagtcagg aagccgcttc
    16981 tattgcacaa gagataaagc gtctacctta attataaaga tttgtaaata taaccgtctc
    17041 cggtatgttg cctgaggcgg tttttttgtc tctaacgtgc ggaaaaattt gttcctcttc
    17101 acattttttg tacaaccgac atgcccgtgt agctcacaaa tatgacagtg gcgtgaattt
    17161 tgcgcattga cggcagttat gattcgcggt attgcttaac tgtgattgca catttagtaa
    17221 tcactgtttt cttttccacc agaaaccagt atgagggaaa cgaggcatga agagacaaaa
    17281 acgagatcgc ctggaacggg cacatcaacg tggttatcag gccggcatcg ccggacgctc
    17341 aaaagaaatg tgtccctatc agacgctgaa tcaaaggtca caatggctgg gaggctggcg
    17401 agaagccatg gcggacaggg tagtaatggc ctgattctgt ctctttaaaa agaaacctcc
    17461 gcattgcgga ggtttcgcct tttgatactc tgtctgatta taatcagaag gcagacgtat
    17521 cctggaacag accgactttc aggtcgctgg cggtatagat cagacgacca tcaaccagca
    17581 cttcgccatc cgccaggccc ataatcagac gacggttaac aatgcgttta aagtgaatac
    17641 ggtaggtcac ttttttcgct gtcggcagta cctgaccagt gaatttcact tcgccaacgc
    17701 ccagcgcgcg gcctttacct tcgccgccca gccagccgag gtagaaccct accagctgcc
    17761 acattgcgtc caggcccagg catcccggca taaccggatc gccaataaag tggcatccga
    17821 agaaccacag atccggattg atatccagtt ctgcttcaac ataccctttg tcgaagttac
    17881 cacccgtttc ggtcattttg accacacggt ccatcatcag catgttcggt gctggcaatt
    17941 gcgggccttt agcgccaaac agttcaccgc gaccagaggc aagaaggtct tcttttgtat
    18001 aggattcgcg tttatctacc atgttctctg taagccttat tttattgaag cacgcaggat
    18061 agctaacacg tgtacgctga acaagtccga tcagttcgga ataaaccagt tcagccaacg
    18121 taatggccat ggaaaacggt gacgtccttc ctgttgcgat gcttgcgcga tacgttcctg
    18181 gatggtttgc atcagcgtcg tttggccttc gccatcccac accagattta ataataacgg
    18241 cagtgcgtca gtcacatcgt ctactgccca gatggtgaat ttgccttctt ctaccgcttt
    18301 caccagttca ctgtgaagac ttaaatggcg aacgttagct gtggggataa tgacaccttg
    18361 tttcccggtt aactcacgtt gctggcaaat agcaaagaag ccttcgattt tctcatttaa
    18421 accaccgacc ggctgggcgc gaccgaactg atcgactgaa cctgtgatag cgatactctg
    18481 attcaccggc acatcggcga gggcgcttat cagggcgcag agttcagcca tcgaggcact
    18541 atctccatca acttcactgt atgactgctc aaatgtcagc gatgctgaga aggggatctg
    18601 ttgctcaagc tgtagttccg acatcaggaa cgcttgcatg atcatcatcc ctttcgcatg
    18661 gatattgccg ccaagctccg ctttgcgttc gatgtcggtg aattcaccat cgccaatatg
    18721 cacaacgcag ctaatgcgag aaggttcgcc aaaagcgcgt ggatgacccg gaaattcaat
    18781 gaccgaaagg gcgttaattt gcccgatgcg ttcgccttcg gtttcaatca ggatttgctc
    18841 ctgaaggatc tcatcctgca tacgttcagc gaggaaacct tcgcgccatt cacgctgctg
    18901 cagcattaag tttagctgct cgccggagaa ggtgtcgcca tcacacaggg aggcgacctc
    18961 tttacactgg cggaggatcc actgcgggct aagcggaagt gtttcttgtt caccggtgta
    19021 gcgtgctgct tcgcggataa gtatcggcca ggcatccgct cccggtgcag gtaagtgatt
    19081 atgtctggcg gtaaatgtca cccagcgaca ccactgggtt actgactccg catcgacaat
    19141 ctgcagagta tcttcaaatt cgctataaat agcctgctct gaaagctctg gctccatctc
    19201 ctggaaatca gccaatgatt cgcgttcgcc taccagaatg actttcagct tcaatggcat
    19261 cgaaggcaca gagacgggga gagggcgcga ctcatcaaac gcaacccagt caaaacgctc
    19321 gcggttaacg atatttttca gccgcatcca cagcagaggt tgcgccagca gtgtacgcaa
    19381 agagataatg agaataccgc catttgcctg atgcaccaga ccaggctgca gggtaatgtc
    19441 gccattaaac tggcgcaggc agccaaagag ttgctccgct tctacccagt cggcagcgac
    19501 aacttgcgtt aaagtcgcaa aattatcatc tgcactcact gcgtgacgta agcggatgga
    19561 gtggccggaa acctcatagt gaccgcccac cagttggcct gcatcgcttt gtagcgtacg
    19621 cgcggcattg gcaataagat tcagatactc agactcttcc ggggccttcg ccagcataaa
    19681 agaggaggat gctcgcgtat gcagcaactg ctccagcgca aattgcagcc gcggttgagt
    19741 atcactgaat aaaggatcgt tttcgtcaat caaatgtggc tgagcaaata tttcctgata
    19801 gctatcggta tcaggaacca ggtcacgcca tgcaagtttc ttaatggtca aagttgatgt
    19861 tttttagtct gttgtcaaag ccgcgattat accgtaaccg gcactacagc acacgtagaa
    19921 agcaccgaca atactcctgg catgggcgtt aaagctcaca ggatggagat tcttttcttc
    19981 actggcctaa aaagctgata ttctgtaaag agttacacgg taacattgag atcgctatga
    20041 aatatcaaca acttgaaaat cttgaaagcg gttggaaatg gaagtatctg gttaagaagc
    20101 atcgcgaagg ggagttaatc acccgttaca tagaagccag tgccgcccag gaagccgtcg
    20161 atgtgttgct ctcgctggaa aatgaacccg tgctggtaaa tggctggatt gacaagcata
    20221 tgaatccgga actggtcaat cgcatgaagc aaaccattcg ggcaagacga aagcgccatt
    20281 ttaatgcgga acaccagcat acgcgcaaaa aatcgatcga tctggaattt attgtctggc
    20341 aacgtctggc tggtcttgcg cagcgtcgcg gtaaaacgct ttctgaaacg attgttcagc
    20401 tgattgaaga tgcggaaaac aaagagaaat acgcgaataa aatgtcttct ctgaagcagg
    20461 atctgcaggc attgctgggt aaggaataac tgacgaaagt cagttcaatt tactaaaggc
    20521 aaaaaaaacc ccgcagcagc ggggtttttc taccagacga gaacttaagc ctgcggctga
    20581 gttacaacgt ctttgatacc tttaacttcg atctctacgc gacgatccgg agccaggcag
    20641 tcgatcagtg cagcacgctg tttcacgttg tcacaggtgt tgccagtaac cgggttggat
    20701 tcgcccatac cacgtgcgga gatcttgtct gccgggatac ctttggagat caggtaatca
    20761 acaacagact gagcacggcg ctcggacaga ccctggttgt aagcgtcaga accgatgcgg
    20821 tcggtgtaac ccagaacaac tacggaaccg tctttcggat ccaggttgct cagctggctg
    20881 tacagctgat ccagagcagc ctgaccttcc ggtttcaggg ttgctttgtt gaagttgaac
    20941 agaacgtcag acttcagagt gaagtgcttg gtctgtactt ccggtgccgg agctggagcc
    21001 ggagcaacta ctggagctgc ttcgccctga ccgaaacggt aggaaacacc caggctcagc
    21061 atgccgttgt ccggacgagt gccgatggtg tgtgcgtcac cgatgttgtt ggtccactgg
    21121 tattccagac gggtagcgat ttcaggagtg atcgcgtact caacaccgcc agcgaagacc
    21181 ggagaaacgc cggtgtcgtg gtttttacca taaacgttgg atttagtgtc tgcacgccat
    21241 accatgccac ccagacgagt gtagatgtcc aggtcgtcag tgattgggta acccagttta
    21301 gcggtcagtt gaacgccctg agctttgtat gcaccgtttt taacgctgcc tttgtacggc
    21361 atacgaccta accagtcgta acccatttca aagccaacat acgggttaac ctggtaacca
    21421 ccaaaagcac cagcgcccag ttggttttca tgggtcgggc cattgttgtt gatgaaacca
    21481 gtgtcatggt actgggacca gcccagttta gcaccagtgt accaggtgtt atctttcgga
    21541 gcggcctgcg ctacggtagc gaaaccagcc agtgccactg caatcgcgat agctgtcttt
    21601 ttcatttttt gcgcctcgtt atcatccaaa atacgccatg aatatctcca acgagataac
    21661 acggttaaat ccttcaccgg gggatctgct caatattaac tctaccgata tcttcggctt
    21721 atgccgagca cccctggcga tgtaaagtct acaacgtagt tgaaaactta caagtgtgaa
    21781 ctccgtcagg catatgaaaa aaaagtcttg tataaggtat gtttaatctt ttttgtcagc
    21841 gacaatttac agaagagaat cgcggaaacc gcttcagaca agcctccgca aggaaaatta
    21901 gtcacgactg aaagcattgg ctgggcgaca aaaaaagttc caggattaat cctaaattta
    21961 cttaatgata caaattagag tgaattttta gcccggaaag ttgtctcgtg gcgtgagagg
    22021 atgcgcttac cggacgcata ataaacccca tagcgttacc ttcatttgcc gcatcaacaa
    22081 gttcagcatg ctcttcttca gtcaaatcat ctgccaacca accgatcacc acactgtaat
    22141 tgcccgtgcg taaagcgcga accattgact ccacagtgtg gcaaggggag agctggctaa
    22201 tctgcattac tttcgttaag ggtagcccag atgcctgaac ccattcccga ctcagttttt
    22261 gttgcggtgt taaccagagt tgccagcgcg attgctgacc gagttgctgt aacaatggca
    22321 acagtagaag ttgcgtcatc atgggctgat cttcgcgata gacaacttca ctgataagcc
    22381 cggctgtagt gttttccgta gagacacgcg caattttact tgctgcggat gagaacgacg
    22441 aagaacgatg tgcatagcct gaagtgtaca taatcaatcc agcccctgtg agttactgta
    22501 tggatgtaca gtacatccag tgacaacaaa gatcaaccct attttcggaa agagcctcgc
    22561 aaattttgtc gttggtgacg ggaaaacata aattaatctt gccccttaag aataagttgc
    22621 ctattttcgt agttaacgga tccgttaatg tgaatcattc ttttatgtta tgattttaaa
    22681 aggaatttta tgaaaagcct ctcctataag cggatctata aatcacaaga atacctggca
    22741 acgttgggca caattgaata ccgatcattg tttggcagtt acagcctgac cgttgacgac
    22801 acggtgtttg cgatggtttc tgatggtgag ttgtatcttc gggcttgtga gcaaagtgca
    22861 cagtactgtg taaaacatcc gcctgtctgg ctgacatata aaaagtgtgg ccgatccgtt
    22921 accctcaatt actatcgggt tgatgaaagt ctatggcgaa atcaactgaa gctggtgcgt
    22981 ctgtcgaaat attctctcga tgcagcgctg aaagagaaaa gcacgcgcaa tacccgggaa
    23041 agactgaaag atttgcccaa tatgtctttt catctggaag cgattctcgg ggaggtgggg
    23101 attaaggatg tacgggcgtt acgtatactt ggggcaaaaa tgtgttggtt gcgactgcgg
    23161 cagcaaaaca gtctggtgac agaaaagatt ctgtttatgc ttgaaggtgc cattatcggc
    23221 attcatgaag ctgcgctccc ggtggcacgc cgccaggagc ttgcagaatg ggctgactct
    23281 cttacgccga aacaggagtt tcctgcggaa cttgagtaat ctggcgttgc agacgaccaa
    23341 tctcaggcag taatgcaatc aataatccaa cttgttgtac gaccagaggt tctttgctgt
    23401 ctgcccgtgg ttcaagttgc tgcatccgct gtttcaggct agctaatgcc tcattgacgc
    23461 gttcttcatc agcaggttga tgatgtaacg cgtcatcaac atagcaaact gcgtcatcaa
    23521 gaaacgccag aatttcagga ttagttaact gctcccggtg agcaccgagg gctgagatat
    23581 agctggtaaa cgtatggtta aggcacagca accgaaacgc ggcttcgcga atttgcgggg
    23641 taacgttcgg ctcgctggac atatttgata ccaccgacgc cagctcagca tcacggttgt
    23701 gtgcatcgcg gcgggcaata cgatacgcca gacggttatc acgcccctga tggtattgct
    23761 ccagtatggc atcgagatac cgacagttgg cctctgtggc gcgttcgagc atgcgcggca
    23821 gattgcgaaa ctgccagtca ggccagatgt agctcactgc cgcccacgca atggcacaac
    23881 caatcagcgt atcgattacg cgaggtaacg ctacttcaaa accttcaccc agtaagttaa
    23941 aacacagtag caccaaaagt gtgatgaaca tcgttgcatg agcgtattgc acgttacgga
    24001 aggcaaaaaa gagcacgccg gtaataacca gcagcaccag ctgcccttcc agtgatggca
    24061 caaaccacag cacaggaatg ccaatggcga tacctaccag cgtaccaata atccttaact
    24121 tcaggcggtg gcgcgtggcg ttatagtttg gctggcagac aaacaaactt gtcagcaaga
    24181 tccaataccc gtgatgcatt ccggttatct gaatgatggc gtagccgaag cacaacacca
    24241 gcgacattct taccgcatga cggaagaggg cggattccgg cgtgaagtga cggctaagac
    24301 gcagccagat atcactcaac ccgtgcgggc tgtcatcagc gagctcattt tcgtcattat
    24361 tatggggtag tgcctgggcc tgttctgatt caattgttgc cagttgggca tcaatggcgc
    24421 gtaaattgtt cagcaaaaat cccagtgttt tgagtaaatc ggcgggtgcg ccgttatcgc
    24481 gcatccgctc cagcgcagca tcaatatgcg taaaagcgcg ctcaaaatgc ggatcatgtt
    24541 gataaggctg acgcaacaaa atacagcgtg acagttgctg gcacgcctgg cccagcatcg
    24601 acatcagccg ctgaaaacgg aacagcacgt cgctgtggcg aaaatgttca cgcaatgttt
    24661 gatactgaat atgagaagag ctggcacgct cgtgaatatc ctgtgcgaca aagtaataat
    24721 gcagcgtgcg acgcgttccc cgttgaccac gatcgccacg taagcgggtc agcagcgaga
    24781 gtttcgtctg attcaatgtc gccatcagca gaccgttggc gagagccaaa tcgtacagcg
    24841 gtgcctggct ttgatcttca atatcaggat caaacatgcg cgacttgagc tcaagataac
    24901 gcgccagttg ttcatagcaa cgcgccaggt tgtcctgcag cgggcggacc gggaacagca
    24961 gatgaccaat aagtgtcagg acgttgtacc agacggcacc ggccagcaga tacatcggct
    25021 gctgatacca gtgctcatac agtgatgttc ccaacatagt gtaaatggcg atcagcaatg
    25081 caccgaaggc aattgttgca tagcgttgac ccagaccgcc gagcaaaatg aagccgctgg
    25141 tagagagcgt taagccaatc gcaaatagcc agggccaggg aaacagcaat tctactgagg
    25201 ccgaggcgat aaaaaagcag aacagcgtaa tgatgaggtt acgcaaacgt cccgccagtc
    25261 ggtcatcgag atcggtcagc gccgctgcca ccatccccag cgttagcgga atcgtcagtt
    25321 ttacatcacc cagccaccac ggaaacgctg tggttccaca aagcgcaata aaaatacgcg
    25381 cgtaatacag ccaggcgctg ttccaggtat agcgtttgag caaaggactt agcataaagg
    25441 ccatattagt ggattattca aaacgacgac gtgcattggc ttcacgcgca gcttgcgctg
    25501 tttctaccga taccacgcga cgaccaaccg gccatagtgc aatagcggca attttaaagt
    25561 tcgcaatgcc gacaggaatg ccaatgattg aaatacattg tgcgatgccc gttgcaatgt
    25621 gcatcaggca taaccaccag ccaaagaaaa tcagccagaa aatattcaat accgtaccgc
    25681 cagtattcag cagcacattt ttgccagccg ggttcagttc atcgacatga atagcttcat
    25741 tgccataagg caccagagac agtttagtga tctcccagca ggatcgtgtc agcggtaagg
    25801 taaaaatcag cacaatactg accagagtcg ccaacagcca gcccagagtg gtggcaaatc
    25861 cgccaagcac aaagttcaga atgttcaaaa cggtacgcat aaaacctcgc tttactgtgg
    25921 ttttcagtaa tgggcggcaa ttgtaacgtt tttttgggct ggagcacgtt ttctctgacg
    25981 gttacactga taagaaataa tttcgtgtgg atctacagag tcatggaact gaaagcgaca
    26041 acgcttggaa aacgtctggc acagcaccct tacgatcggg cggtgatcct caatgccggg
    26101 attaaagtct ccggcgatcg ccacgaatac cttattcctt tcaatcaatt actggcgatt
    26161 cactgtaagc gcggtctggt atggggcgag ctggaatttg tactgccgga cgaaaaagtg
    26221 gtgcgtctgc acggcaccga atggggcgag acgcagcgtt tttaccatca tcttgatgct
    26281 cactggcggc ggtggagtgg cgagatgagc gaaattgcgt ctggtgtttt acgccagcaa
    26341 ctggatttga ttgccacgcg cactggggaa aataaatggc tgacgcgtga gcaaacctct
    26401 ggcgtgcagc aacaaatccg ccaggctttg tcggcgttgc cgttgccggt taaccgactg
    26461 gaagaattcg ataactgccg tgaggcgtgg cgtaaatgtc aggcctggtt gaaagatatt
    26521 gaaagcgctc ggttgcagca taaccaggcg tataccgaag ccatgcttac cgagtatgcg
    26581 gattttttcc gccaggtcga gtcttcaccg ctgaatccgg cgcaggcccg ggcagtcgtt
    26641 aatggcgagc attctctgtt agtgctggca ggtgcaggaa gcggaaaaac gtcggtgctg
    26701 gtggcccgtg caggctggtt gctggcgcgt ggtgaagcgt cccctgagca aattttattg
    26761 ctggcgtttg gtcgcaaagc cgctgaagag atggacgagc ggattcgcga acggctacat
    26821 accgaagaca ttaccgcacg tacgtttcat gcgctggcgc tgcatattat tcagcagggc
    26881 agcaaaaaag ttccgatagt cagcaaactg gaaaatgata ccgctgcccg tcatgaactc
    26941 tttattgctg agtggcgcaa gcaatgcagc gaaaagaaag cgcaggcgaa gggctggcgg
    27001 caatggctga cggaagaaat gcagtggtca gtgccagaag gtaacttctg ggatgatgaa
    27061 aaattacagc gtcgccttgc ctctcgcctc gatcgctggg taagtctgat gcggatgcac
    27121 ggtggtgcac aggcagaaat gattgccagt gcacccgaag agattcgcga tctgttcagt
    27181 aaacgtatca agttgatggc cccgttatta aaagcctgga aaggtgcgct gaaggcagaa
    27241 aacgctgtcg atttttcggg ccttattcat caggcgattg tgattctgga gaaaggtcgc
    27301 tttatcagcc cgtggaagca tattctggtt gatgaatttc aggatatctc gccgcagcgg
    27361 gcagcgttgt tagcggcatt acgcaagcaa aacagtcaga cgacgttgtt cgctgttggt
    27421 gatgactggc aggcgattta ccgattcagc ggtgcgcaaa tgtcgctcac caccgctttc
    27481 catgaaaact ttggtgaagg cgaacgctgt gatttagaca cgacttaccg ttttaacagt
    27541 cgtatcggtg aggtggcaaa ccggtttatt cagcagaacc caggccagct gaaaaagccg
    27601 ctaaacagct taaccaatgg agacaaaaaa gccgtcacgt tattggatga gagtcaactt
    27661 gacgctttgc tggataagct ctctggttat gccaaaccgg aagagcgcat tctgatcctg
    27721 gcgcgttacc atcacatgag gcctgccagc ctggaaaaag cggcaacacg ctggccgaag
    27781 ttgcaaatcg actttatgac cattcatgcc agcaaagggc aacaggcgga ttacgtcatc
    27841 atcgttggct tgcaggaggg aagtgatggt tttccggctg cggcgcggga gtcgattatg
    27901 gaagaggcgc tactgccacc ggttgaggat ttcccggacg ctgaagaacg gcggttaatg
    27961 tacgtggcgc tgacccgggc acgccatcgg gtatgggcac tgtttaacaa agagaatccc
    28021 tctccctttg tggaaatact gaaaaatctg gatgtgccgg tggcgagaaa accgtaagaa
    28081 acaggtggcg tttgccacct gtgcaatatt acttcagacg gtccgcgaga taacgctgat
    28141 aatcggggat cagaatatcg accgcgtcgt tgaaatgcgg cgactggatt atgaagtctg
    28201 ccgttgccac gttggtggcg accggaatgt tccataccgt cgccagacgc agcaaggctt
    28261 tcacgtcagg atcgtgcggc acggcattta gtggatccca gaagaaaatc aatacatcaa
    28321 ttttcccttc tgagatcaat gcgccaacct gctggtcacc ccccattggg ccactcaaca
    28381 tcgcgttgac gttcatgccg gtcgcgcggg aaattaagtt accggtagtg cctgttgcat
    28441 acagtacgtg ttgttccagt aacggttgat gccgttccac ccagctcatc agcatttgtt
    28501 tgcagtgatc gtgtgccacc agcgcaatat gtttccgcgc aggtaaagtg cgagtcgtca
    28561 gttccataat gtacatccgt agttaacttt cctacagatt actgtaagca cttatcgctg
    28621 caagataaag accgaaaaag cctgcgcaca ggcacaaaaa tctcaggaag atggttgttt
    28681 ttccgcccac tgcaggaaag tatttcgcgt ttgtgggtca gccagtttaa accaatactt
    28741 cagccgttgt tctgtgagca cctgagactg cggtggaata gcatccagct cggaaacacc
    28801 cgaaagcagc gtactgtcat ctgccatcat cgtggcaaat tgcggtagtg aagcgcgttt
    28861 cgcggatttg ttatagcgtt caacctcgac ctcataatca atcgtttttg ccgttgaggt
    28921 aatggcgaga atatccagct ttaccggaat cggcgtcgca tcgccatcca acaattcaag
    28981 gcgcggcgcg gcatcaaaat ggttagcttc ccgctcattc tccaggcgag gcaggcgaaa
    29041 attgacctgg ttgatgagct gggtattaaa actgaccacc agcggtgggg agatatacag
    29101 ccgttcttca ctattggaaa gatgaatcgt cttctcaacg cgaaacacta actgatgcgg
    29161 tccattatcc agttcaatgc tgtccgcacc gcgcagcaga gagctggaaa ccttcttgcc
    29221 gtcgagtacc agaagatcga catcggttga aagccgcagc gtggtggcaa aaacggatac
    29281 cggcaaacat aatgcaatca aggtggtcac gatgccggtt ttcataggta gctcctgtca
    29341 aaagaccgcc cgaataataa tgtgtcaaaa tttttcttta atcatactta ctaacatata
    29401 gacatatttc ccgcttttgc tctcattcat tcgtattagc tgcatggttg gcatgtcggc
    29461 tttgtcgtac actttgttaa acagtctgga ggaaataatg aaagaaaccg atattgcagg
    29521 cattttaacg tccactcaca ccattgcgct ggtgggggca agcgacaaac ccgatcgtcc
    29581 cagctatcgc gtgatgaaat atctactcga ccaggggtat cacgtcattc cggtttcgcc
    29641 aaaagttgcc ggcaaaacgc tgctgggcca gaaggggtat ggcacgctgg cagacgttcc
    29701 ggaaaaagtc gatatggtcg atgttttccg taattcagaa gcggcgtggg gcgtggcaca
    29761 ggaagctatt gccattggcg cgaaaaccct ctggatgcaa ctgggggtga ttaatgagca
    29821 agcggcagta ctggcacggg atgccgggtt aaatgtggtg atggatcgct gcccggctat
    29881 tgagatccct cgcctgggcc tggccaaata aaaaatcccc ggaaggcaaa aaccttccgg
    29941 ggatttgttc agggattagt tacgcagacg cggggcctgg agttgtttgc ggatggtctg
    30001 cgccagctca tccatggatg gctgttcagg atgttcatcc tgcaattcgc tacttagctg
    30061 ggcttcagcc aggtaggtat gaaccggtag gccgttatcg tcctccatca ctacgtgata
    30121 ccacggagcg gcgcgaagct cgtcattcac cgccagctca tcaggcgacg gttcagagag
    30181 cgaataaacc gggtcgatat ccacgaccac tccgagataa cctaacaggg aatggcggac
    30241 ctgctggccg ataccgaatt tgctggcaat catagtcacc tcccgggaaa tctttacctt
    30301 tgatataagg gtaaaattcc acatttcaag ttacatgacg cgacaggcaa accctttcag
    30361 atatagccct tccggatagg tagcgatcac cggatgatcg gctgcctgac ggaactgctc
    30421 tataaattgt acatcacgac cggcatcaat tgcggcatcc gcgatgattt tctgaaataa
    30481 atcgctggtc atcagaccgg aacaggagaa agtcaggaga ataccgcctt cattcagcag
    30541 ctgaatcgcc agcatgttga tgtctttata accacgacac gcgcccatca actggctttt
    30601 attctcaaca aacttcggcg ggtccatcac gataacgtca aatttttcac cgcgatcgcg
    30661 ataagtacgc agcaatttaa agacatcatc acggacaaac tcagccttgc tcagatccag
    30721 tttgttcagc tcaacgttct gccgtgcaat atccagcgct tcctgggagg tatcaacgct
    30781 gacaacctgg ctgcaaccgc ccatcagtgc cgatacggcg aaaccaccgg tataggagaa
    30841 acagttcagc acacgtttat tttcaacgta gcggcgggta gccaggcggc tatcacgctg
    30901 gtccaggtag tagcccgttt tgtgtccgtg ctgaatatcc accagcagtt tcattccgtg
    30961 ttcttcaatc ggcagcaggg caggtggcaa ctcgccggtg acggggccct gggtcagctc
    31021 cattccttct tttttacgta ccgcgacgtc gctgcgatcg taaatcgaac attccgggta
    31081 cagcgtttgc agggcactaa ttaatgccgc gcgctgatat tctgccccag cactcagcag
    31141 ttgcagcacc agaaaattac cgaaacgatc gatagtaata cccggcaggc catcagattc
    31201 tccggcgatt aaacgatagc tgtcgaggcc atctttttgc gccagccagt cacgccattt
    31261 ttgtgcttgt tgcaaacggc gggaaaaaaa agcaatgtcg atagactcag acgggtcaaa
    31321 cgtccagacg cgcgcccgga tttgcgaagc tggcgaataa gcgccgcgtg ctaaccattt
    31381 tccctgatga tcaacaatat cgatggtttc accgaggctg gctttacctt ccatgcgggc
    31441 aacggccccg gaaaagaccc acggatggcg acgaagtaat gatttttcgc gccctttggc
    31501 taacactaaa cgtacactca taatttactt ttctgtcgat gcaaagaaat gggcgtcatt
    31561 gtccggagtt ttccatggat ttgcaacgcg tccattaagg ataaggagag cagcaatgtc
    31621 gaaagtctgc ataattgcct gggtttacgg gcgagttcag ggcgtaggat ttcgctacac
    31681 cacacagtac gaagcgaaaa gactgggttt aaccgggtac gccaaaaatc ttgacgatgg
    31741 cagcgtggaa gtggttgctt gcggtgaaga agggcaggtg gaaaaattaa tgcagtggtt
    31801 aaagagtggc ggcccgcgtt ctgcgcgtgt agaacgggtg ctcagcgagc cgcatcatcc
    31861 ctcgggggaa ttaaccgatt ttcgtatccg ttaaatacat tttaccggtt ttggcaggcc
    31921 agcaattttg gtggcttgct tagccggacc tttcggaaac agtcggtata aatagcggct
    31981 gttacctttt tcttcgccaa atttattcgc catcgctttt accagcatac gaatcgccgg
    32041 agaagtattg aattccagat agaaatcacg cacaaaacgc accacttccc agtgttccgg
    32101 tgacagcgaa atcccttcgt tctctgcaat caccacagcc agcggctcac tccactggct
    32161 gctttctttg agatagcctt cggtatccgt ttctatctct ttaccttcga agatcagcat
    32221 aattattact accttaatca gactggcggc agtgtaacaa aaaacaaagc cccgcataaa
    32281 gcgaggctat gaaagtgtta gcgggtgaga ttaatcgcgg ctagcgaagc ccagaatgct
    32341 cagcaggctg acgaagatgt tgtacagcga aacatacagg ctaaccgtgg cacgaatata
    32401 gttcgtctca ccgccatgaa tgatgttgct ggtttcaaac aagatagcgc cagaggagat
    32461 cagaatgaag accgcgctga tcgccagatg cagagcaggc agctgcagga agatattcgc
    32521 aaccatacca atcagcacca ccacaatacc cgccatcagc ataccgccga ggaacgacat
    32581 atctttgcgg gtggtcagca catatgcaga gcagcagaag aacactaacg ccgttccgcc
    32641 cagtgccata gcgattacgt cacccattcc ggcagacaga taggtgttca gaataggtcc
    32701 gaggatataa cccagaaaac cggtaaaggc gaatgcggag ataatcccgg tcggcttatt
    32761 cgccgtttta taggtcagga acatcaaacc atacataccc accagcgtca gaatcagacc
    32821 cggagatggc agcatcagca ccgtactggc agttgcggta atcgccgaaa aggccagcgt
    32881 caggctcagc agaaaatagg tattacgcag caccttatgg gtgctaagca gtgatgtacg
    32941 gtcatgtgaa gaactaacaa tacgatccat tgagtcactc tctatgacag atgtaattaa
    33001 ttaagcagca taatgataat gcgtaagggc acccagaagt tttacccatc tttacgcatt
    33061 tgatctggaa caggtttaac agcggattat caggtcatta agcaaatata acgccctgag
    33121 aatttcgaca ggcaaaagaa aaaggggtta gcatttagct aaccccttat cttatttggc
    33181 ggaagcgcag agattcgaac tctggaaccc tttcgggtcg ccggttttca agaccggtgc
    33241 cttcaaccgc tcggccacac ttccggaatg acgcgcacta taaacatccc gatgcggcgt
    33301 gtaaacccct aatttgtttg tttgcctgaa aaacagccaa aagtgcattg atagcgtgaa
    33361 ataacagcag attgatcatt tcatcaccat gaattccttc tcttttactc gtttagcaac
    33421 cggctaaaca tccccaccgc ccggccaaaa gaaaaatagg tccattttta tcgctaaaag
    33481 ataaatccac acagtttgta ttgttttgtg caaaagtttc actacgcttt attaacaata
    33541 ctttctggcg acgtgcgcca gtgcagaagg atgagctttc gttttcagca tctcacgtga
    33601 agcgatggtt tgccttgcta cagggacgtc gcttgccgac cataagcgcc cggtgtcctg
    33661 ccggtgtcgc aaggaggaga gacgtgcgat atgaataacg aggaaacatt ttaccaggcc
    33721 atgcggcgtc agggcgttac ccggcgcagc tttctcaaat attgtagtct ggctgccacg
    33781 tcgctgggat taggcgcggg aatggcacca aagattgcct gggcgctgga gaacaaaccg
    33841 cgcattccgg tggtatggat ccacggtctg gaatgcacct gctgtaccga atcttttatc
    33901 cgctccgctc acccactggc gaaggacgtc atcctttccc tgatttccct cgattacgac
    33961 gatactttga tggctgccgc cggaacccag gcggaagaag tctttgaaga catcatcacg
    34021 caatacaatg gcaaatatat cctcgcagta gaaggtaatc cgccgctggg cgagcagggg
    34081 atgttctgta tcagcagcgg tcgaccgttt attgagaaac tcaaacgtgc cgctgccgga
    34141 gccagcgcga ttatcgcctg gggaacctgc gcgtcctggg gctgcgtgca ggccgcgcga
    34201 cccaatccga cgcaggcaac gcctatcgac aaagtcatca ccgacaaacc cattatcaaa
    34261 gtacctggct gcccgccgat cccggatgtg atgagcgcca tcattactta catggtgacc
    34321 tttgatcgct tgccagatgt cgacagaatg ggccgtccgc tgatgttcta tggtcagcga
    34381 atccacgata aatgctatcg ccgcgcccac ttcgacgccg gagagttcgt ccagagttgg
    34441 gatgatgacg ctgcccgcaa aggttactgc ctgtacaaaa tgggctgcaa agggcctacc
    34501 acctataacg cctgttcctc cacacgctgg aatgatggcg tttctttccc aatccagtct
    34561 ggtcacggct gcctgggctg tgcggaaaat ggtttctggg atcgcggttc gttctacagc
    34621 cgcgtggtcg atattccgca aatgggtact cattccaccg ccgataccgt cggtttaacc
    34681 gcgcttggcg tggtggcagc ggctgttggt gtgcacgcag tcgccagcgc cgttgaccag
    34741 cgcagacgtc ataaccagca acctacagaa accgaacatc agccaggcaa tgaggataaa
    34801 caggcatgag cactcagtac gaaactcagg gatacaccat caataatgcc ggacgccgcc
    34861 tggtggtcga cccgattacg cgcatcgaag gccacatgcg ctgcgaagtg aatattaacg
    34921 atcagaatgt gatcaccaat gccgtctcct gcggcaccat gtttcgcggg ctggagatca
    34981 tcctacaagg gcgcgacccg cgcgatgcgt gggcgttcgt tgaacgtatc tgcggcgtct
    35041 gtactggcgt acacgccctg gcttcggttt acgccatcga agatgctatc ggtattaaag
    35101 tgccggacaa cgccaatatc atccgcaaca ttatgctggc aacgctctgg tgccacgatc
    35161 atctggtgca cttctatcag cttgccggga tggactggat cgatgtgtta gatgcgctga
    35221 aagccgaccc gcggaaaacc tccgaactgg cgcaaagtct ctcctcttgg ccgaaatcat
    35281 cccctggcta tttcttcgac gtacaaaacc gcctgaaaaa atttgttgaa ggcgggcagt
    35341 tggggatctt ccgcaatggc tactgggggc acccgcagta caaactgccg ccagaagcta
    35401 acctgatggg ctttgcccac tatctcgaag ctctcgattt ccagcgtgaa attgtcaaaa
    35461 tccacgcggt ctttggcggt aaaaacccgc atccaaactg gattgtcggc gggatgcctt
    35521 gcgccatcaa cattgacgaa agcggcgcgg tcggggcagt caatatggaa cgcctgaacc
    35581 tggtgcagtc aattatcacc cgcacggcgg acttcattaa caacgtgatg atccccgacg
    35641 ccttagccat cggtcagttc aacaaaccgt ggagcgaaat cggcactggt ctttctgata
    35701 aatgcgttct cagctacggc gcattcccgg atattgccaa cgactttggc gagaaaagtc
    35761 tgctgatgcc tggcggcgcg gtgattaacg gcgacttcaa caatgtgctg ccagtggatt
    35821 tggttgatcc gcagcaggtg caggagtttg tcgaccacgc ctggtatcga tatcccaacg
    35881 atcaggtcgg gcgtcatccg ttcgatggca tcaccgaccc gtggtacaac cccggcgatg
    35941 tcaaaggcag cgataccaac attcagcagc tgaatgaaca ggaacgctac tcgtggatca
    36001 aagcgccacg ctggcgcggt aacgcgatgg aagtggggcc gctggcgcgc acgttaatcg
    36061 cttatcacaa aggcgatgct gcgaccgttg agtcggtcga tcgcatgatg tcggcgttga
    36121 acctgccgct ttccggtatc cagtcaacgt taggccgcat tttgtgccgc gcgcacgaag
    36181 cgcagtgggc cgcaggtaag ttgcagtatt tcttcgacaa gctgatgacc aacctgaaaa
    36241 acggcaatct cgccactgct tccacggaaa aatgggaacc tgcaacctgg ccgacagagt
    36301 gccgtggtgt cggttttacc gaagcgccgc gcggggcgtt aggccactgg gccgccattc
    36361 gcgatggcaa gattgatctc taccagtgcg tggtgccgac cacctggaac gccagcccgc
    36421 gcgatcccaa agggcagatt ggcgcttatg aagcggcgct gatgaacacc aaaatggcga
    36481 tccccgagca accgctggag atcctgcgta ctctgcacag ctttgacccg tgcctcgcct
    36541 gttcaacaca cgtgctgggc gacgacggta gcgagctgat ctccgtgcag gtgcgttaac
    36601 agcgaaggag aatcatcatg caacagaaaa gcgacaacgt tgtcagccac tatgtctttg
    36661 aagcgccagt gcgcatctgg cactggttga cggtgttatg catggcggtg ttgatggtca
    36721 ccggatactt tatcggcaag ccgctacctt ccgtcagcgg cgaggcgacg tatctgttct
    36781 atatgggcta catcaggtta attcacttca gcgccgggat ggtttttacc gtggttttgc
    36841 tgatgcggat ctactgggct tttgttggca atcgatactc ccgcgagctg tttatcgtgc
    36901 cggtatggcg taaaagctgg tggcagggcg tgtggtatga aatccgctgg tatctgtttc
    36961 tggcaaaacg tccgagtgcc gatataggcc ataatcccat cgcccaggcg gcgatgttcg
    37021 gctatttcct gatgtcggtc tttatgatca tcactggttt tgcgctgtac agcgaacaca
    37081 gccagtacgc tatttttgcg ccgttccgtt atgtggtgga atttttctac tggacgggtg
    37141 gcaactcaat ggacattcac agctggcatc ggctggggat gtggctgatt ggcgcgtttg
    37201 tgatcggtca tgtctacatg gcgctgcgtg aagacatcat gtccgacgac acggtgatct
    37261 ccaccatggt caacggctac cgtagccaca aatttggcaa aataagtaac aaggagcgtt
    37321 catgagcgag caacgcgtgg tggtcatggg gctgggcaac ctgctgtggg ccgatgaagg
    37381 cttcggcgtg cgggtggcgg aacggctgta tgcccattac cactggcccg agtatgtgga
    37441 gattgtcgat ggcggtactc agggactgaa cttgctgggg tatgtcgaaa gcgccagcca
    37501 tctgttgatt ctcgatgcca ttgactacgg gctggaacct ggaacgctgc gaacctatgc
    37561 cggagaacgc attccggctt atctcagcgc gaagaaaatg agcctgcatc agaacagttt
    37621 ctccgaagtg ttggcgctgg cggatatccg cggacatctg ccagcacata ttgccctcgt
    37681 cggtctgcaa cccgcaatgc tcgacgacta cggcggtagc ctgagcgaac tggcacggga
    37741 gcaactgccc gctgcggaac aggcggcgct ggcgcagctt gctgcgtggg gaattgtgcc
    37801 gcaaccggct aatgaatcgc gctgtctcaa ttatgactgt ctgtcgatgg aaaattacga
    37861 aggcgttcgc ttgcgccagt accggatgac acaggaggag cagggatgag caacgacacg
    37921 ccatttgatg cgttgtggca acgaatgctg gcgcgcggct ggacgccagt cagtgaatcc
    37981 cgtcttgacg actggcttac gcaagcgcca gacggcgtgg tgttattaag cagtgacccg
    38041 aaacgcacgc cagaggtcag cgataatccg gtaatgattg gcgaattact gcgcgagttt
    38101 cccgactata catggcaggt ggcgattgct gaccttgagc agagcgaagc catcggcgat
    38161 cgctttggcg tctttcgctt tcctgccact ttagtgttta ccggcggaaa ctatcgcggc
    38221 gtgctgaatg gtattcaccc gtgggcggaa ctgataaacc tgatgcgcgg gcttgtcgaa
    38281 ccgcagcagg agcgtgtctc atgagcgaaa cttttttcca tctgctgggg ccaggaacgc
    38341 aaccgaacga tgacagtttc agcatgaatc cactgccgat cacctgtcag gtgaatgatg
    38401 aaccgagtat ggcggccctg gagcaatgtg ctcacagccc gcaggtgatt gcgctgttaa
    38461 acgagttaca acatcaacta agcgaacgcc aaccgccgtt gggcgaggtg ctggcagtcg
    38521 atctgttaaa tctcaacgcc gacgatcgtc actttatcaa tacgcttctc ggggaagggg
    38581 aagtgtcagt gcgcattcag caggctgacg acagtgaaag tgaaatacag gaggcgatct
    38641 tctgcggatt atggcgggtg cgcagacgtc gcggcgaaaa gttgctggag gacaaactgg
    38701 aggctggctg cgcgccgctg gcgttgtggc aggcggcaac gcaaaatctc ttgccgacag
    38761 attcgctgtt accgccgccc attgatggcc tgatgaatgg cctaccgttg gcgcatgagt
    38821 tactggcaca tgtacgtaac cccgacgcgc agccgcacag cattaatctg acgcaattac
    38881 ccatcagcga ggctgatcgg ctttttctct cacgtctctg tgggccggga aatattcaga
    38941 ttcgtaccat tggctatggc gagagctata tcaacgccac ggggttacgc catgtctggc
    39001 atttacgctg tacggacacc ttaaaaggcc cgttactgga aagttatgaa atctgcccaa
    39061 taccggaagt ggtgctggca gcgccagaag atttggtcga ttctgcgcag cggcttagcg
    39121 aggtatgtca gtggctggcg gaagctgcac cgacgtaaaa agacggtaag tatcgctttc
    39181 agtcttatga atatcgcaat cggcgaatac ctctggtcgt agagtttcag gataaagagg
    39241 gagatctacc attatcgggt tatttttctc tcttcgccta caggagtgcg catgtgggat
    39301 gtcattgatt tatcgcgctg gcagtttgct ctgaccgcgc tgtatcactt tttatttgta
    39361 ccccttaccc tggggctgat ttttttgctg gctattatgg aaaccattta cgtggtcacc
    39421 ggcaaaacaa tctaccgcga tatgacgcgc ttctggggta agctcttcgg tatcaatttt
    39481 gctcttggcg tggctaccgg cctgaccatg gagtttcagt ttggtactaa ctggtcattc
    39541 tattccaact atgtgggcga tatttttggc gcaccgctgg cgatggaagc attaatggcc
    39601 ttcttcctcg aatccacctt tgtcgggctg ttcttcttcg gctggcaacg gctgaataaa
    39661 taccagcacc tgctggtgac gtggctggtg gcgttcggtt caaatctctc tgcgttgtgg
    39721 atattgaatg ccaacggttg gatgcaatac ccgaccggtg cgcattttga tatcgacacc
    39781 ctgcgtatgg agatgaccag cttcagcgag ctggtcttta atccggtcag ccaggtgaaa
    39841 tttgtgcaca ccgtaatggc gggctacgtg accggggcca tgtttattat ggcgatcagc
    39901 gcctggtatt tactgcgcgg acgggagcgc gatgtcgcat tacgctcgtt tgccatcggt
    39961 tccgtcttcg gtactctggc gattatcggt accctgcaac tcggagacag ttctgcgtat
    40021 gaagtcgcgc aagtacaacc ggtaaaactg gcggcgatgg aaggggagtg gcaaacggaa
    40081 cctgcacctg caccgttcca tgtggttgcc tggccggaac aggatcaaga gcgtaacgcc
    40141 tttgccctca aaattcccgc gctgctaggg atcctcgcca ctcactcatt agataaaccc
    40201 gtgccgggtc tgaagaattt gatggctgaa acctacccac gcttgcaacg cggacgtatg
    40261 gcctggctgt taatgcagga aatatcgcaa ggcaatcgtg agccgcatgt gttgcaggca
    40321 ttccggggac tggaaggtga cctgggctac ggcatgttgc tctcccgcta tgcgccggat
    40381 atgaatcatg tcacagccgc acagtaccag gcggcgatgc gtggcgcgat acctcaggtt
    40441 gcgccggtat tctggagttt ccgcatcatg gtgggctgtg gttccctgct gctactggtg
    40501 atgctgattg cgcttgtcca gacgctgcgt ggcaaaatcg accagcatcg ctgggtgctg
    40561 aaaatggcgc tctggagttt gccgttgccg tggattgcga ttgaagccgg gtggtttatg
    40621 accgagtttg gtcgtcagcc gtgggcgata caggacatct taccgacata ctccgcgcac
    40681 tccgctttaa ccacaggaca actggctttc tcactgatca tgatcgtagg gctttacacc
    40741 ctgttcttaa tcgccgaagt ctacctgatg cagaaatatg cccgtctggg gccgagcgcg
    40801 atgcagagtg aacaaccgac gcagcaacag gggtaaagga gaaaatcatg tttgattatg
    40861 aaacattgcg cttcatctgg tggctgctga ttggcgtgat cctggtggtc tttatgatct
    40921 ccgacggatt tgacatgggg atcggctgtc tgctgccgct ggtggcgcgt aatgatgatg
    40981 aacgccggat agtgataaac agcgttggtg cacactggga aggcaaccag gtctggttga
    41041 tcctcgctgg tggggcatta tttgccgcct ggcccagagt gtatgcagcg gcgttttccg
    41101 gcttttatgt ggcgatgatc ctggtgctgt gctcactgtt cttccgcccg ctggcctttg
    41161 attatcgcgg aaaaatcgcc gatgcacgct ggcgtaaaat gtgggacgcc ggtctggtca
    41221 tcggcagtct ggtgccgccg gtagtcttcg gtatcgcctt cggcaacttg ttgctcggcg
    41281 tgccgtttgc cttcacaccg caattacgcg tggagtatct cggcagcttc tggcaactgc
    41341 tgacgccatt ccctttattg tgcggattgc tcagccttgg gatggtgatt ttgcaaggtg
    41401 gcgtctggtt acaactgaaa actgttggtg tgattcatct gcgttcacag ctggcgacca
    41461 aacgcgctgc actgttggtg atgctgtgct ttttgctggc gggttactgg ctgtgggtcg
    41521 gtattgatgg ctttgtactg ctcgcccagg atgctaacgg tccttccaat ccgttaatga
    41581 aactggtggc agtgctacct ggtgcctgga tgaataattt tgtcgagtcg cccgttttgt
    41641 ggatcttccc gctgctggga ttcttctgcc cattgctgac ggtgatggcg atttatcgtg
    41701 gtcgcccggg ttggggattt ttgatggcat cattgatgca atttggcgtg attttcacgg
    41761 caggcatcac gctgttcccc tttgtcatgc cgtcaagcgt gagtccgatc tccagcctga
    41821 cgttgtggga cagtacttcc agtcagctga cgctgagcat tatgttggta atcgtgctga
    41881 tatttttgcc cattgtgttg ctctacactc tctggagcta ctacaaaatg tgggggcgca
    41941 tgacaacaga aactctccgc cgtaacgaaa acgagttgta ctaaggagca gaaacaatgt
    42001 ggtatttact ttggttcgtc ggcattttgt tgatgtgttc gctctccacc cttgtgttgg
    42061 tatggctgga cccgcgtctg aaaagttaac gaacgtaggc ctgatgcggc gcattagcat
    42121 cgcatcaggc aatcaataat gtcagatatg aaaagcggaa acatatcgat gaaagcgatc
    42181 ttaatcccat ttttatctct tctgattccg ttaaccccgc aatctgcatt cgctcagagt
    42241 gagccggagc tgaagctgga aagtgtggtg attgtcagtc gtcatggtgt gcgtgctcca
    42301 accaaggcca cgcaactgat gcaggatgtc accccagacg catggccaac ctggccggta
    42361 aaactgggtt ggctgacacc gcgcggtgga gagctaatcg cctatctcgg acattaccaa
    42421 cgccagcgtc tggtagccga cggattgctg gcgaaaaagg gctgcccgca gtctggtcag
    42481 gtcgcgatta ttgctgatgt cgacgagcgt acccgtaaaa caggcgaagc cttcgccgcc
    42541 gggctggcac ctgactgtgc aataaccgta catacccagg cagatacgtc cagtcccgat
    42601 ccgttattta atcctctaaa aactggcgtt tgccaactgg ataacgcgaa cgtgactgac
    42661 gcgatcctca gcagggcagg agggtcaatt gctgacttta ccgggcatcg gcaaacggcg
    42721 tttcgcgaac tggaacgggt gcttaatttt ccgcaatcaa acttgtgcct taaacgtgag
    42781 aaacaggacg aaagctgttc attaacgcag gcattaccat cggaactcaa ggtgagcgcc
    42841 gacaatgtct cattaaccgg tgcggtaagc ctcgcatcaa tgctgacgga gatatttctc
    42901 ctgcaacaag cacagggaat gccggagccg gggtggggaa ggatcaccga ttcacaccag
    42961 tggaacacct tgctaagttt gcataacgcg caattttatt tgctacaacg cacgccagag
    43021 gttgcccgca gccgcgccac cccgttatta gatttgatca agacagcgtt gacgccccat
    43081 ccaccgcaaa aacaggcgta tggtgtgaca ttacccactt cagtgctgtt tatcgccgga
    43141 cacgatacta atctggcaaa tctcggcggc gcactggagc tcaactggac gcttcccggt
    43201 cagccggata acacgccgcc aggtggtgaa ctggtgtttg aacgctggcg tcggctaagc
    43261 gataacagcc agtggattca ggtttcgctg gtcttccaga ctttacagca gatgcgtgat
    43321 aaaacgccgc tgtcattaaa tacgccgccc ggagaggtga aactgaccct ggcaggatgt
    43381 gaagagcgaa atgcgcaggg catgtgttcg ttggcaggtt ttacgcaaat cgtgaatgaa
    43441 gcacgcatac cggcgtgcag tttgtaatgc ataaaaaaga gcattcagtt acctgaatgc
    43501 tctgaggctg atgacaaacg aagaactgtc taatgcgtag accggaaaag gcgttcacgc
    43561 cgcatccggc cactttcagt tttactcttt ctcggagtaa ctataaccgt aatagttata
    43621 gccgtaactg taagcggtgc tggcgcgttt aatcacacca ttgaggatag cgcctttaat
    43681 attgacgcct gcctgttcca gacgctgcat tgacaaactc acctctttgg cggtgttcaa
    43741 gccaaaacgc gcaaccagca ggctggtgcc aacagaacgc cccacgaccg cggcatcact
    43801 caccgccagc atcggcggcg tatcgacaat caccagatcg taatggtcgt tcgcccattc
    43861 cagtaattga cgcatccgat cgcgcatcag cagttcagac gggttaggtg gcacctgacc
    43921 gcgagtaatc acatcaaagc ctcctttgcc aaaatgctgg atcactttgt tgagctcatc
    43981 tttacctgcc agatattccg acaagccatg ttcattactc acggtaaaca ggttatgcga
    44041 ataaccacgg cgtaagtcgg catcaataaa taacactttt tgatcggact gggcgatcac
    44101 cgctgccaga gttgaactga caaacgtttt accactgtct ggcgtcgcac cggtgatcat
    44161 tagaatgtta ttctccgtct ccatcatagc gaaatgcaga ctggttcgta gcgcacgtac
    44221 ggcttccaca gcagaatccg ccgggttatc caccgccagg aaggggatat ttttagtacg
    44281 atggcgctgc tgattagaaa ataaattttt cttacgcaga cgggtgcgtt tatccagcca
    44341 ctcggacatt gggatagtgg cataaacgct gatgccgtgc tcttccagtt gttccggggc
    44401 ttctacacca cgacgcaaca tcgcacgcgc cagcacggca cccacagaaa taaacaggcc
    44461 aagaataaaa ccaagcacca cgttcaacgc ttttttcggt ttcactggct gcggctgagt
    44521 gactgccggg tcgataatcc gcacgttacc aatggcactg gatttcgaaa tactcaactc
    44581 ctgctggcgg ttaagtaatt gcagatatac cgcacggccc gcttctacgt cacgacttaa
    44641 acgcaacact tcctgttggg tggaaggcat tgccgatacc cgcttattca ggcgtttgcg
    44701 ttcttgctcc agcgtctggc gtttttccag cagcgcacga taagttgggt gatctttctt
    44761 atacagctgg gagatctctg cctcgcggaa ggtcagctca ttgagttgat tatcaacgtt
    44821 cacaatctgc tcaagaacgg ctttggcttc caggttaagg tcaaccgaat cgcgctgctg
    44881 gcgataaacg ttgagttttt cttccgcttg gtccagctcg ctgcgcactt caggtaactg
    44941 gcgctgtaag aattcaaggc tttgtgaatc ctgcgccgcc tggcgagcga tattctgttg
    45001 caaatagttg ttagcgatgc tgttcagaat acgagtaatc aactggggat catcaccagc
    45061 catggtaagt tccagcatcc cgctttcttt actgcgttcg ctaacggtaa aggtttcctg
    45121 caatgcgtta atcgcttcca gttcggtacg ctggctcagg acaaactgtg ttcctggttt
    45181 ggccttaatg tccgcgatag tcagcgcaac gccatctttt tccagacgct ggccgaccat
    45241 accattgacg gtgaactctt caccttccag tgtatagtgg ccgttttccc caaccgtgag
    45301 tgtcagttgc tgatcctgac cattcagttg tggaatatgc atccagctga tcgccagctc
    45361 acctggtttt tctttggtta atctcgccca gccgcgaccc acaatcggaa aatacttctg
    45421 ctcaactatg tcgcgcagat tcagttcagc aatggtttta ccgagaatca tgcgcgattg
    45481 cagcagttgg atctccggtg cagactcggg cgatgagtta gggatcatat cgctcaggcc
    45541 gctgagaatg gcgttgccct gtttttgctc aacctggacc agagtatctg cctgataaat
    45601 tggtgtgctt aacagcgagt aagcgacagc gatcagcgtg aataacgcgg tcacgctgat
    45661 aataaactta cggtgatccc ataactcgcc gaccagacga agcagatcga tctcattttc
    45721 ctgagtgctg cctggtggcg tattcatatt tttagttgtc atcgtatttt ataaactcaa
    45781 attaccggct gaggcgcttc gcccattcct gactggcgcg ctccaacata ccgtagacat
    45841 gttcaaatgc gtcctgactt ttacgatagg gatccgggat ctctttctgt tccagccatt
    45901 gcccaaacag cattgtcttc ccgcggacct cgggagcaat tgcggtaacc tgagcaatat
    45961 gttccgactc cttgccagaa tcagatcgta atttcgtgcc atctcagcag tgagcttacg
    46021 tccggcatgt ccttcaagag atacgccatg attagcggca acatctgccg ctgtcgcatc
    46081 tgcagggtgt tttaccagac catgaacacc tgccgatttg acttttacgc ccggcagacg
    46141 tttacgcagc aagcgctcgc caatgggcga acggcaaatg ttgccggtac aaaccaccag
    46201 gattgagtta aattttagtt gggccatgtt tgaatccacc gtgaagtctc tgtcaggtca
    46261 tgcaccccgg aaatcgtcgg taccagcaga gaaatcacac ggttccaacg agccagcggc
    46321 gcggtagtga cataaacaat gtcgtaaggt tcaagctgga attccgttcc gagtatcatt
    46381 gccgatgcgt ccttcgcatt cagctgataa atattggcga ttttgccatt ctgcttgttt
    46441 tgcgttgcac gaataacaaa aatccccgtc gcatcagcga catcctgatt cataccctca
    46501 gcgttaccca gcgcttccgc cagggtcata ccgctgcggt ccattttcag cgtgctctgt
    46561 ttacccactt cacccatcac gaagactttc agatcatcgt tgcgcggaat aaataaaata
    46621 tcgcccgggt gcagcagttt gttctggcgc aagtcgccac gctgcatcag cgcatagagg
    46681 ttcactttgg tctttacgcc attctgggtg agcaccacgt tgcgccagtc tgcatctgcg
    46741 gtcagaccgc ccgcggcgtt aatcgcatcc atgatggtca gaggaatatt ggtaatcggc
    46801 tgctgacccg atttgctgac ttcgccggtg acgtacgctt tttgcgatcg gaacgccgcg
    46861 acgctgacat cgacttgcgg gctttcaatg actgaatcga gacgcgctgt aatctcgttg
    46921 cgtacctggg taagtgtttt cccggccact ttcaggcgac caatataggg gtagaaaatc
    46981 gcaccatcgg cgttaaccca gttgccggta tcactggcgc tacggtattg ccctgcgggg
    47041 gtggttagtt ccgggtgatc ccagaccgta accatcaaca catcaccaat cccgatacga
    47101 tattcatagt ttgcgatttg ctgctccagc tccgggttag cctgcgacat aatcggtttg
    47161 gcgcgcaact gatcaatcaa tcctggcgtg acgggataga tattgaccat tttgtccagg
    47221 tcatactgat tgtcaggtag ttcaatgaca tccttgttac tggtcgataa attctgacca
    47281 ggaacaaggg tacatgctgt caaagacaga acagccaatg tcagtaccga aaacttaaaa
    47341 atgttctttt tcattggttt atatttatca gtcaatgtaa tgttatgaat tacgtcaggt
    47401 tattgtccaa ccggtacttc tcgctctgcc gtcattggat agagctggta tttgcgtgac
    47461 agcatttgtc caccatcacg cgtcaatggt gtccacgaaa ccaccgcgcg gttgcggtta
    47521 ggtccaatgg tcatcaagtc gaatggaatc gagatataaa aacctttact aaagccgcct
    47581 tcgccgtagt catctttaga tacgttactg attgccgccc atacccctac cgccacgccg
    47641 ctgtcaaagc gtttggcgac gtcgatcgtt gcgcctttat cttttgccag atattgccca
    47701 acgctaagtt tcatcagtac gccattgagc gtcggcgggt tccagtaagc cgtcacgaaa
    47761 cctgttggcg tggaataatc ggtgaaacgc atcatgttgt cccagtcacg ttgcttcacg
    47821 tagttaacgt ccacacccag cgcccagcag gcatctagcg ggcgataaag cagctcggaa
    47881 ccgacaccgg cgtacatcgt ttccagataa ccgccataca cctggccata gaaaccattg
    47941 cctaagtcag caaaatagtt cgcctgcaag ttgttgagat aaacgtcatt gcgaacgtag
    48001 tcacggatat gcgtgcgcac gcggggcagg gtagagtccg cgggcaacag cgaagactta
    48061 aacttgtcgt agttgttgta aatattggtg aaaataccgc catcaagcag caggtggtcg
    48121 gtaaaccagt agcgggcact ggacatcagc cccagctgga acatatagaa atcttccggg
    48181 ccgcccagcg actgtgaaag tgttgggttg aaagagtagc taaagcgatc ttcacgaata
    48241 cggtagcccc gaccaaaggc agaaagatct tcagcttcaa cacgttgttg ttgcagtggc
    48301 tctgattgac caggcgctgt acctgccagc tgtttgcgca ggctggctac gtcggtttcg
    48361 gtagtcacca tcgccatatg ctcgcgcttt tgcgtcacgc taatcttctc aacgccttgc
    48421 ggcaggttat tcaccagaat ccggttggca cgatcgaccg cttcacgaga gtcacggtat
    48481 ttgtattgct gaccagacat atacagtgtc ttatcgcgta gctgaatttc tggcgcgtca
    48541 aagcccgcgt tatacttcag ggcggtaagt tggtttgcta ccgtggtgta ctgcaatcct
    48601 tcagattcag gcgcaggttg atatgccggt tttggcgtat cgcgcagggc agggcgcaga
    48661 tcgttgaaat tggtccgtaa cgtgaagcca aacatcaacg tgttaccgcg ttcataactc
    48721 aggttgagat ctgcccagct ggcagcgcga taaactgcgc cgacgttgaa atggcttgcc
    48781 tgaggcagtt tgccagcgaa atcattctgg taattgtttc catcgtattc gagtttcaga
    48841 cgcaggggat tccacggcgt ttgatactca atgccgccaa agatggaagc cgggccacga
    48901 aagatatcgc taaagctgat atcgcccgca tcgtgagact ctgcgcgatg acaatattta
    48961 tcgctcaccc ggcaaaacgg gttggtaata ttgcccgcat taccggcgta gccccatgcc
    49021 atcccgaggg tgaaatcaaa tggccccgct tgcttgctgg ccaccagata ctcaccgtca
    49081 aacagacccg taccagcaat atcacgttta ccaaacgcca cttgcggtag ccagtaacct
    49141 tcttcccaca ggcgaagttt aaaatcgaat gatttgtctt tgtatgactg atcgccgctg
    49201 aaatcttccc actggctata tttgcgtgtg cgcacatccg tataacgaat ggtgccttcc
    49261 agccatggga acagcgccac ggaggtggag tagaaccggt attgatcgtt atcccggtag
    49321 ttgacgctga attcaccttc cggtgcgatg cgcgcatttg gcatctgcaa caatcctgtg
    49381 ccgccaaagt ctgattgcga cgaacccagc ggatccgggt aggttaatac ttcagcatga
    49441 caggcactgg agacggcaat ggccaggcag cttaaaagat aagaattctt cttcatcagt
    49501 caggaacacg ttgcgttaaa acagacacaa tctggtcatt taaatcagca tatttttcgg
    49561 gcagtacatg cgcagaaaag cccaaccaaa gctggctgcc aggcggtggt tccacatgtc
    49621 ttttattcca cagggcaaca ggggcgacga cagtctcacc ctcaggcgta atcaccataa
    49681 cgttattctt gtccgcgcct gcaaggcggg ggtgatcttg cagataatcg gtaacgctac
    49741 ggcctgcctg ccagggcaat tgcccggccc cagaaaccgc acccagcaga gtaatagtca
    49801 ccggacgctg tacggtatag agcgtatagt ccccgaccaa cgggggattg ctgttctcat
    49861 ccactcgtac aaaatcaggg tccagtttga ccggtaagcg accagtgata ttgagattga
    49921 gtaactgctg gcgcacggat ttaatcgttg ccgccacatc gtcgtcagct tctgcttccc
    49981 aggaagcaag ctgtgccatg acatgttggt agtctttaag cgctttagct ttcgccgcag
    50041 agtcggtcag caaggcacca ggccaccaga ggcgatcgcg cagttgcggt tgtgtcacca
    50101 actggacaac attttccacg gggccaacgg aaagtgtctg ttgttcgcca ggcagataaa
    50161 tagtcaccgt tccttgcgca aaggcatggg gtgtcattac gtaaagtacg ctggcaatga
    50221 aatacgactg taatttattc atggtgcggg tttaagaaac gtcatttcta cgggaataac
    50281 ccctgcgcct aacatttgcc gactttgacg aacctggcca gtagccgaat cgacccagaa
    50341 tgtgttttgc cactgttttt ctggccgcgt ggaagtcacc tcttcctgcc agacattaca
    50401 cagcacattg cgacccgcaa tattcagcgt ctctaatcca gcaaaggaaa aagtagaact
    50461 cagggtcgca gagcgaaaat ggttgtcttc actccagaga atatcgcgcg tccagcggct
    50521 gccatctttt attgccagcg cgttacgcag agggtcctgc ccggaatttg tcacttccag
    50581 cagattatta ttaagtttga cggtttttaa aagacgtcca ttgtgggtaa ccagcatggc
    50641 gttatcctgg gataaccatt tgctttgttc ttgttctata tatcccagta ccacaaagat
    50701 tcgttgccct tcattaaggc gtaaatacat agtggaataa ggcaacgcct ggatctgctg
    50761 atccgctacg gtgatatcct gattatcgaa aaggctggcg cgaaatgtat cgaccatact
    50821 ttgctggctg tgcgtacatc ccgcaagaaa tagtgcgaaa atcgataaaa taagagggcg
    50881 cacctttaat ccttgaaagg ttaattaaaa aaatgcaaat ctctaaagcc cggtacgaat
    50941 atcgcaaccg ggtatcattt aactttaatt ttgacgcgtt aaagcagtat tagcgtgtag
    51001 tggacgtggt ggttgaggtg ttatgagaac cgccatcgcc actgtcattt gctgcaacaa
    51061 ctgccaacgt cgccacacca acagccgttg ccacaccgac aactgtcgcc gtgccgacag
    51121 cgccagcagc cacgccacca gtggtagtag cagtcgtggt tgcgccggta gtggtcgttg
    51181 tggtgccagt agtacccgtc gttgcctcgg tcccgtttgt tgcttcaggg gcagcaaacg
    51241 cagctggcgt cgtcaacatg aaggccataa ggattgcaga aagcttgtgt ttcataactt
    51301 ttcctttatt catcgcatgg acaatacgta cgcttgagat caggattgtc tactttgagt
    51361 ataacatcct tgtgaaatct ccctttcctc ataccgcttg cactatatac tgcgggtagg
    51421 aaaggcgcgc agagggaaat ataagattgt taactatccc cctctggaaa tacgacttgt
    51481 gggcataaga taaatcttag caaaa
//
LOCUS       DAPOAV010000023        51501 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.023, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000023 DAPOAV010000000
VERSION     DAPOAV010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 51501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51501
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.023"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            186..857
                     /locus_tag="RN951_001613"
     CDS             186..857
                     /locus_tag="RN951_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016241930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDX2526626.1"
                     /translation="MDKVLDSALLSSANKRKGILAIGAHPDDIELGCGASLARLAQKG
                     IYIAAVVMTTGNSGTDGIIDRHEESRNALKILGCHQTIHLNFADTRAHLQLNDMISAL
                     EDIIKNQIPSDVEIMRVYTMHDADRHQDHLAVYQASMVACRTIPQILGYETPSTWLSF
                     MPQVFESVKEEYFTVKLAALKKHKSQERRDYMRHDRLRAVAQFRGQQVNSDLGEGFVI
                     HKMIL"
     gene            867..2063
                     /locus_tag="RN951_001614"
     CDS             867..2063
                     /locus_tag="RN951_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDX2526627.1"
                     /translation="MKTWIFICMSIAMLLWFLSTLRRKPSQKKGCIDAIIPAYNEGPC
                     LAQSLDNLLRNPYFCRVICVNDGSTDNTEAVMAEVKRKWGDRFVAVTQKNTGKGGALM
                     NGLNYATCDQVFLSDADTYVPPDQDGMGYMLAEIERGADAVGGIPSTALKGAGLLPHI
                     RATVKLPMIVMKRTLQQLLGGAPFIISGACGMFRTDVLRKFGFSDRTKVEDLDLTWTL
                     VANGYRIRQANRCIVYPQECNSPREEWRRWRRWIVGYAVCMRLHKRLLFSRFGIFSIF
                     PMLLVVLYGVGIYLTTWFNEFITTGPHGVVLAMFPLIWVGVVCVIGAFSAWFHRCWLL
                     VPLAPLSVVYVLLAYAIWIIYGLIAFFTGREPQRDKPTRYSALVEASTAYSQPSVTGT
                     EKLSEA"
     gene            2041..2622
                     /locus_tag="RN951_001615"
     CDS             2041..2622
                     /locus_tag="RN951_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012602184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDX2526628.1"
                     /translation="MKNYLKLNVKEKNIQIADQVIIDETAGEVVIGANTRICHGAVIQ
                     GPVVIGANCLIGNYAFIRPGTIISNGVKIGFATEIKNAVIEAEATIGPQCFIADSVVA
                     NQAYLGAQVRTSNHRLDEQPVSVRTPEGIIATGCDKLGCYIGQRSRLGVQVIILPGRI
                     ISPNTQLGPRVIVERNLPTGTYSLRQELIRTGD"
     gene            2624..3397
                     /locus_tag="RN951_001616"
     CDS             2624..3397
                     /locus_tag="RN951_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiO family outer membrane beta-barrel protein"
                     /protein_id="HDX2526629.1"
                     /translation="MIKRTLLAAAIFSALPAYAGLTSITAGYDFTDYSGDHGNRNLAY
                     AELVAKVENATLLFNLSQGRRDYETEHFNATRGQGAVWYKWNNWLTTRTGIAFADNTP
                     VFARQDFRQDINLALLPKTLFTTGYRYTKYYDDVEVDAWQGGVSLYTGPVITSYRYTH
                     YDSSDAGGSYSNMISVRLNDPRGTGYTQLWLSRGTGAYTYDWTPETRYGSMKSVSLQR
                     IQPLTEQLNLGLTAGKVWYDTPTDDFNGLQLAARLTWKF"
     gene            3585..3860
                     /gene="frmR"
                     /locus_tag="RN951_001617"
     CDS             3585..3860
                     /gene="frmR"
                     /locus_tag="RN951_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414891.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formaldehyde-responsive transcriptional
                     repressor FrmR"
                     /protein_id="HDX2526630.1"
                     /translation="MPSTPEEKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAA
                     VRGAANGLMAEVLESHIRETFDRNDCYSREVSQSVDDTIELVRAYLK"
     gene            3895..5004
                     /gene="frmA"
                     /locus_tag="RN951_001618"
     CDS             3895..5004
                     /gene="frmA"
                     /locus_tag="RN951_001618"
                     /EC_number="1.1.1.284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-(hydroxymethyl)glutathione dehydrogenase"
                     /protein_id="HDX2526631.1"
                     /translation="MKSRAAVAFAPGKPLEIVEIDVAPPKKGEVLIKVTHTGVCHTDA
                     FTLSGDDPEGVFPVVLGHEGAGVVVEVGEGVTSVKPGDHVIPLYTAECGECEFCRSGK
                     TNLCVAVRETQGKGLMPDGTTRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEAN
                     HEHVCLLGCGVTTGIGAVHNTAKVQPGDSVAVFGLGAIGLAVVQGARQAKAGRIIAID
                     TNPKKFDLARRFGATDCINPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALES
                     AHRGWGQSVIIGVAGAGQEISTRPFQLVTGRVWKGSAFGGVKGRSQLPGMVEDAMKGD
                     IDLEPFVTHTMSLDEINDAFDLMHEGKSIRTVIRY"
     gene            5098..5931
                     /gene="fghA"
                     /locus_tag="RN951_001619"
     CDS             5098..5931
                     /gene="fghA"
                     /locus_tag="RN951_001619"
                     /EC_number="3.1.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HDX2526632.1"
                     /translation="MELIEKHVSFGGWQNVYRHYSQSLKCEMNVGVYLPPKAANEKLP
                     VLYWLSGLTCNEQNFITKSGMQRYAAEHNIIVVAPDTSPRGSHVADADRYDLGQGAGF
                     YLNATQAPWNEHYKMYDYIRNELPDLVMHHFPATAKKSISGHSMGGLGALVLALRNPD
                     EYVSVSAFSPIVSPSQVPWGQQAFAAYLAENKDAWLDYDPVSLISQGQRVAEIMVDQG
                     LSDDFYAEQLRTPNLEKICQEMNIKTLIRYHEGYDHSYYFVSSFIGEHIAYHANKLNM
                     R"
     gene            complement(6155..6694)
                     /locus_tag="RN951_001620"
     CDS             complement(6155..6694)
                     /locus_tag="RN951_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414888.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2058 domain-containing protein"
                     /protein_id="HDX2526633.1"
                     /translation="MAKLTLQEQLLKAGLVTSKKAAKVERTAKKSRVQAREARAAVEE
                     NKKAQLERDKQLSEQQKQAALAKEYKAQVKQLIEMNRITIANGDIGFNFTDGNLIKKI
                     FVDKLTQAQLINGRLAIARLLVDNNSEGEYAIIPASVADKIAQRDASSIVLHSALSAE
                     EQDEDDPYADFKVPDDLMW"
     gene            complement(6796..8007)
                     /locus_tag="RN951_001621"
     CDS             complement(6796..8007)
                     /locus_tag="RN951_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414887.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-(3-hydroxy-phenyl)propionate transporter"
                     /protein_id="HDX2526634.1"
                     /translation="MSTRTPSSSSSRLMLTIGLCFLVALMEGLDLQAAGIAAGGIAQA
                     FALDKMQMGWIFSAGILGLLPGALVGGMLADRYGRKRILIGSVALFGLFSLATAIAWD
                     FPSLVFARLMTGVGLGAALPNLIALTSEAAGPRFRGTAVSLMYCGVPIGAALAATLGF
                     AGANLAWQTVFWVGGVVPLILVPLLMRWLPESAVFAGEKQSAPPLRALFAPETATATL
                     LLWLCYFFTLLVVYMLINWLPLLLVEQGFQPSQAAGVMFALQMGAASGTLMLGALMDK
                     LRPVTMSLLIYSGMLASLLALGTVSSFNGMLLAGFVAGLFATGGQSVLYALAPLFYSS
                     QIRATGVGTAVAVGRLGAMSGPLLAGKMLALGTGTVGVMAASAPGILVAGLAVFILMS
                     RRSRIQPCADA"
     gene            complement(8585..9598)
                     /gene="dmpG"
                     /locus_tag="RN951_001622"
     CDS             complement(8585..9598)
                     /gene="dmpG"
                     /locus_tag="RN951_001622"
                     /EC_number="4.1.3.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="HDX2526635.1"
                     /translation="MNGKKLYISDVTLRDGMHAIRHQYSLENVRQIAKALDDARVDSI
                     EVAHGDGLQGSSFNYGFGAHSDLEWIEAAADVVKHAKIATLLLPGIGTIHDLKNAWQA
                     GARVVRVATHCTEADVSAQHIQYARELGMDTVGFLMMSHMTTPENLAKQAKLMEGYGA
                     TCIYVVDSGGAMNMSDIRDRFRALKAELKPETQTGMHAHHNLSLGVANSIAAVEEGCD
                     RIDASLAGMGAGAGNAPLEVFIAAADKLGWQHGTDLYALMDAADDLVRPLQDRPVRVD
                     RETLALGYAGVYSSFLRHCETAAARYGLSAVDILVELGKRRMVGGQEDMIVDVALDLR
                     NNK"
     gene            complement(9595..10545)
                     /gene="mhpF"
                     /locus_tag="RN951_001623"
     CDS             complement(9595..10545)
                     /gene="mhpF"
                     /locus_tag="RN951_001623"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase"
                     /protein_id="HDX2526636.1"
                     /translation="MSKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGL
                     ARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSAGAHVKNDAALREAKPDIRLIDL
                     TPAAIGPYCVPVVNLEANVDQLNVNMVTCGGQATIPMVAAVSRVARVHYAEIIASIAS
                     KSAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEAS
                     QDDIEASINEMAEAVQAYVPGYRLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEV
                     EGAAHYLPAYAGNLDIMTSSALATAEKMAQSLARKAGEAA"
     gene            complement(10542..11351)
                     /gene="mhpD"
                     /locus_tag="RN951_001624"
     CDS             complement(10542..11351)
                     /gene="mhpD"
                     /locus_tag="RN951_001624"
                     /EC_number="4.2.1.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414884.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-4-pentenoate hydratase"
                     /protein_id="HDX2526637.1"
                     /translation="MTKHTLEQLAADLRRAAEQGEAIAPLRDLIGIDNAEAAYAIQHI
                     NVQHDVAQGRRVVGRKVGLTHPKVQQQLGVDQPDFGTLFADMCYGDNEIIPFSRVLQP
                     RIEAEIALVLNRDLPATDITFDELYNAIEWVLPALEVVGSRIRDWSIQFVDTVADNAS
                     CGVYVIGGPAQRPAGLDLKNCAMKMTRNNEEVSSGRGSECLGHPLNAAVWLARKMASL
                     GEPLRTGDIILTGALGPMVAVNAGDRFEAHIEGIGSVAATFSSAAPKGSLS"
     gene            complement(11361..12227)
                     /gene="mhpC"
                     /locus_tag="RN951_001625"
     CDS             complement(11361..12227)
                     /gene="mhpC"
                     /locus_tag="RN951_001625"
                     /EC_number="3.7.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414883.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-6-oxonona-2,4-dienedioate hydrolase"
                     /protein_id="HDX2526638.1"
                     /translation="MSYQPQTEAATSRFLNVEEAGKTLRIHFNDCGQGDETVVLLHGS
                     GPGATGWANFSRNIDPLVEAGYRVILLDCPGWGKSDSVVNSGSRSDLNARILKSVVDQ
                     LDIAKIHLLGNSMGGHSSVAFTLKWPERVGKLVLMGGGTGGMSLFTPMPTEGIKRLNQ
                     LYRQPTIENLKLMMDIFVFDTSDLTDALFEARLNNMLSRRDHLENFVKSLEANPKQFP
                     DFGPRLAEIKAQTLIVWGRNDRFVPMDAGLRLLSGIAGSELHIFRDCGHWAQWEHADA
                     FNQLVLNFLARP"
     gene            complement(12245..13189)
                     /gene="mhpB"
                     /locus_tag="RN951_001626"
     CDS             complement(12245..13189)
                     /gene="mhpB"
                     /locus_tag="RN951_001626"
                     /EC_number="1.13.11.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-carboxyethylcatechol 2,3-dioxygenase"
                     /protein_id="HDX2526639.1"
                     /translation="MHAYLHCLSHSPLVGYVDPAQEVLDEVNGVIASARERIAAFSPE
                     LVVLFAPDHYNGFFYDVMPPFCLGVGATAIGDFGSAAGELPVPVELAEACAHAVMKSG
                     IDLAVSYCMQVDHGFAQPLEFLLGGLDKVPVLPVFINGVATPLPGFQRTRMLGEAIGR
                     FTSTLNKRVLFLGSGGLSHQPPVPELAKADAHMRDRLLGSGKDLPASERELRQQRVIS
                     AAEKFVEDQRTLHPLNPIWDNQFMTLLEQGRIQELDAVSNEELSAIAGKSTHEIKTWV
                     AAFAAISAFGNWRSEGRYYRPIPEWIAGFGSLSARTEN"
     gene            complement(13191..14855)
                     /locus_tag="RN951_001627"
     CDS             complement(13191..14855)
                     /locus_tag="RN951_001627"
                     /EC_number="1.14.13.127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid
                     hydroxylase"
                     /protein_id="HDX2526640.1"
                     /translation="MAIQHPDIQPAVNHSVQVAIAGAGPVGLMMANYLGQMGIDVLVV
                     EKLDKLIDYPRAIGIDDEALRTMQSVGLVDDVLPHTTPWHAMRFLTPKGRCFADIQPM
                     TDEFGWPRRNAFIQPQVDAVMLEGVSRFPNVRCLFSRELEAFSQQDDEVTLHLKTAEG
                     QREIVKAQWLVACDGGASFVRRTLNVPFEGKTAPNQWIVVDIANDPLSTPHIYLCCDP
                     VRPYVSAALPHAVRRFEFMVMPGETEEQLREPQNMRKLLSKVLPNPDNVELIRQRVYT
                     HNARLAQRFRIDRVLLAGDAAHIMPVWQGQGYNSGMRDAFNLAWKLALVIQGKARDAL
                     LDTYQQERRDHAKAMIDLSVTAGNVLAPPKRWQGTLRDGVSWLLNYLPPVKRYFLEMR
                     FKPMPQYYGGALMREGEAKHSPVGKMFIQPKVTLENGDVTLLDNAIGANFAVIGWGCN
                     PLWGMSDEQIQQWRALGTRFIQVVPEVQIHTAQDNHDGVLRVGDTQGRLRSWFAQHNA
                     SLVVMRPDRFVAATAIPQTLGKTLNKLASVMTLTRPDADVSVEKVA"
     gene            14932..15879
                     /gene="mhpR"
                     /locus_tag="RN951_001628"
     CDS             14932..15879
                     /gene="mhpR"
                     /locus_tag="RN951_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator MhpR"
                     /protein_id="HDX2526641.1"
                     /translation="MIFYCALSIGRVFSATIKTCPNVHQVHHVVLTIEMSINMQNNEQ
                     TEYKTVRGLTRGLMLLNMLNKLDGGASVGLLAELSGLHRTTVRRLLETLQEEGYVRRS
                     PSDDSFRLTIKVRQLSEGFRDEQWISALAAPLLGDLLREVVWPTDVSTLDVDAMVVRE
                     TTHRFSRLSFHRAMVGRRLPLLKTASGLTWLAFCPEQDRKELIEMLASRPGDDYQLAR
                     EPLKLEAILARARKEGYGQNYRGWDQEEKIASIAVPLRSEQRVIGCLNLVYMASAMTI
                     EQAAEKHLPALQRVAKQIEEGVESQAILVAGRRSGMHLR"
     gene            15956..17038
                     /gene="lacI"
                     /locus_tag="RN951_001629"
     CDS             15956..17038
                     /gene="lacI"
                     /locus_tag="RN951_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414879.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor LacI"
                     /protein_id="HDX2526642.1"
                     /translation="MKPVTLYDVAEYAGVSYQTVSRVVNQASHVSAKTREKVEAAMAE
                     LNYIPNRVAQQLAGKQSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERS
                     GVEACKAAVHNLLAQRVSGLIINYPLDDQDAIAVEAACTNVPALFLDVSDQTPINSII
                     FSHEDGTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRNQIQPIAEREG
                     DWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDT
                     EDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLAPNT
                     QTASPRALADSLMQLARQVSRLESGQ"
     gene            17161..20235
                     /gene="lacZ"
                     /locus_tag="RN951_001630"
     CDS             17161..20235
                     /gene="lacZ"
                     /locus_tag="RN951_001630"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HDX2526643.1"
                     /translation="MTMITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEAR
                     TDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPEADTVVVPSNWQMHGYDAPIYT
                     NVTYPITVNPPFVPTENPTGCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWV
                     GYGQDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHK
                     PTTQISDFHVATRFNDDFSRAVLEAEVQMCGELRDYLRVTVSLWQGETQVASGTAPFG
                     GEIIDERGGYADRVTLRLNVENPKLWSAEIPNLYRAVVELHTADGTLIEAEACDVGFR
                     EVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSH
                     YPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRN
                     HPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTTATDIICPMYARVD
                     EDQPFPAVPKWSIKKWLSLPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGG
                     FVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQ
                     QQFFQFRLSGQTIEVTSEYLFRHSDNELLHWMVALDGKPLASGEVPLDVAPQGKQLIE
                     LPELPQPESAGQLWLTVRVVQPNATAWSEAGHISAWQQWRLAENLSVTLPAASHAIPH
                     LTTSEMDFCIELGNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSE
                     ATRIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTAHAWQHQGKTLFISRKT
                     YRIDGSGQMAITVDVEVASDTPHPARIGLNCQLAQVAERVNWLGLGPQENYPDRLTAA
                     CFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETS
                     HRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK"
     gene            20287..21540
                     /gene="lacY"
                     /locus_tag="RN951_001631"
     CDS             20287..21540
                     /gene="lacY"
                     /locus_tag="RN951_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactose permease"
                     /protein_id="HDX2526644.1"
                     /translation="MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSD
                     TGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYN
                     ILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALCASIVGI
                     MFTINNQFVFWLGSGCALILAVLLFFAKTDAPSSATVANAVGANHSAFSLKLALELFR
                     QPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFGYVTTMGELLNASIM
                     FFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKTLHMFEVPFLLVGCF
                     KYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMYESIGFQGAYLVLCLVALGF
                     TLISVFTLSGPGPLSLLRRQVNEVA"
     gene            21606..22217
                     /gene="lacA"
                     /locus_tag="RN951_001632"
     CDS             21606..22217
                     /gene="lacA"
                     /locus_tag="RN951_001632"
                     /EC_number="2.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactoside O-acetyltransferase"
                     /protein_id="HDX2526645.1"
                     /translation="MNMPMTERIRAGKLFTDMCEGLPEKRLRGKTLMYEFNHSHPSEV
                     EKRESLIKEMFATVGENAWVEPPVYFSYGSNIHIGRNFYANFNLTIVDDYTVTIGDNV
                     LIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVWIGSHVVINPGVTIGDNSVIGA
                     GSIVTKDIPPNVVAAGVPCRVIREINDRDKHYYFKDYKVESSV"
     gene            complement(22320..23501)
                     /gene="cynX"
                     /locus_tag="RN951_001633"
     CDS             complement(22320..23501)
                     /gene="cynX"
                     /locus_tag="RN951_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308421.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyanate transporter CynX"
                     /protein_id="HDX2526646.1"
                     /translation="MRNHQKTFTMLLVLVLIGLNMRPLLTSVGPLLPQLRQASGMSFS
                     VAALLTALPVVTMGGLALAGSWLHQHVSERRSVAISLLLIAVGALMRELYPQSALLLS
                     SALLGGVGIGIIQAVMPSVIKRRFQQRTPLVMGLWSAALMGGGGLGAAITPWLVQHSE
                     TWYQTLAWWALPAVVALFAWWWQSAREVASSHKTTTTPVRVVFTPRAWTLGVYFGLIN
                     GGYASLIAWLPAFYIEIGASAQYSGSLLALMTLGQAAGALLMPAMARHQDRRKLLMLA
                     LVLQLVGFCGFIWLPMQLPVLWAMVCGLGLGGAFPLCLLLALDHSVQPAIAGKLVAFM
                     QGIGFIIAGLAPWFSGVLRSISGNYLMDWAFHALCVVGLMIITLRFAPVRFPQLWVKE
                     A"
     gene            complement(23507..23977)
                     /gene="cynS"
                     /locus_tag="RN951_001634"
     CDS             complement(23507..23977)
                     /gene="cynS"
                     /locus_tag="RN951_001634"
                     /EC_number="4.2.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyanase"
                     /protein_id="HDX2526647.1"
                     /translation="MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVT
                     AALLGQQALPADAARLVGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYRFYEMLQ
                     VYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF"
     gene            complement(24008..24667)
                     /gene="cynT"
                     /locus_tag="RN951_001635"
     CDS             complement(24008..24667)
                     /gene="cynT"
                     /locus_tag="RN951_001635"
                     /EC_number="4.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase CynT"
                     /protein_id="HDX2526648.1"
                     /translation="MKEIIDGFLKFQREAFPKREALFKQLATQQSPRTLFISCSDSRL
                     VPELVTQREPGDLFVIRNAGNIVPSYGPEPGGVSASVEYAVAALRVSDIVICGHSNCG
                     AMTAIASCQCMDHMPAVSHWLRYADSARVVNEARPHSDLPSKAAAMVRENVIAQLANL
                     QTHPSVRLALEEGRIALHGWVYDIESGSIAAFDGATRQFVPLAANPRVCAIPLRQPTA
                     A"
     gene            24776..25675
                     /gene="cynR"
                     /locus_tag="RN951_001636"
     CDS             24776..25675
                     /gene="cynR"
                     /locus_tag="RN951_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414872.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator CynR"
                     /protein_id="HDX2526649.1"
                     /translation="MLSRHINYFLAVAEHGSFTRAASALHVSQPALSQQIRQLEESLG
                     VPLFDRSGRTIRLTDAGEVWRQYASRALQELGAGKRAIHDVADLTRGSLRIAVTPTFT
                     SYFIGPLMADFYARYPSITLQLQEMSQEKIEDMLCRDELDVGIAFAPVHSPELEAIPL
                     LTESLALVVAQHHPLAVHEQVALSRLHDEKLVLLSAEFATREQIDHYCEKAGLHPQVV
                     IEANSISAVLELIRRTSLSTLLPAAIATQHDGLKAISLAPPLLERTAVLLRRKNSWQT
                     AAAKAFLHMALDKCAVVGGNESR"
     gene            complement(26012..27295)
                     /gene="codA"
                     /locus_tag="RN951_001637"
     CDS             complement(26012..27295)
                     /gene="codA"
                     /locus_tag="RN951_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine/isoguanine deaminase"
                     /protein_id="HDX2526650.1"
                     /translation="MSNNALQTIINARLPGEEGLWQIHLQDGKISAIDAQSGVMPITE
                     NSLDAEQGLVIPPFVEPHIHLDTTQTAGQPNWNQSGTLFEGIERWAERKALLTHDDVK
                     QRAWQTLKWQIANGIQHVRTHVDVSDATLTALKAMLEVKQEVAPWIDLQIVAFPQEGI
                     LSYPNGEALLEEALRLGADVVGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDE
                     IDDEQSRFVETVAALAHHEGMGARVTASHTTAMHSYNGAYTSRLFRLLKMSGINFVAN
                     PLVNIHLQGRFDTYPKRRGITRVKEMLESGINVCFGHDDVFDPWYPLGTANMLQVLHM
                     GLHVCQLMGYGQINDGLNLITHHSARTLNLQDYGIAAGNSANLIILPAENGFDALRRQ
                     VPVRYSVRGGKVIASTQPAQTTVYLEQPEAIDYKR"
     gene            complement(27285..28544)
                     /gene="codB"
                     /locus_tag="RN951_001638"
     CDS             complement(27285..28544)
                     /gene="codB"
                     /locus_tag="RN951_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDX2526651.1"
                     /translation="MSQDNNFSQGPVPQSARKGVLALTFVMLGLTFFSASMWTGGTLG
                     TGLSYHDFFLAVLIGNLLLGIYTSFLGYIGAKTGLTTHLLARFSFGVKGSWLPSLLLG
                     GTQVGWFGVGVAMFAIPVGKATGLDINLLIAVSGLLMTVTVFFGISALTVLSVIAVPA
                     IACLGGYSVWLAVNGMGGLDALKAVVPAQPLDFNVALALVVGSFISAGTLTADFVRFG
                     RNAKLAVLVAMVAFFLGNSLMFIFGAAGAAALGMADISDVMIAQGLLLPAIVVLGLNI
                     WTTNDNALYASGLGFANITGMSSKTLSVINGIIGTVCALWLYNNFVGWLTFLSAAIPP
                     VGGVIIADYLMNRRRYEHFATTRMMSVNWVAILAVALGIAAGHWLPGIVPVNAVLGGA
                     LSYLILNPILNRKTTAAMTHVEANSVE"
     gene            complement(28874..30760)
                     /gene="prpE"
                     /locus_tag="RN951_001639"
     CDS             complement(28874..30760)
                     /gene="prpE"
                     /locus_tag="RN951_001639"
                     /EC_number="6.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate--CoA ligase"
                     /protein_id="HDX2526652.1"
                     /translation="MSFSEFYQRSINEPEQFWAEQARRIDWQTPFTQTLDHSNPPFAR
                     WFCEGRTNLCHNAIDRWLEKQPEALALIAVSSETEEERTFTFRQLHDEVNAVASMLRS
                     LGVQRGDRVLVYMPMIAEAHITLLACARIGAIHSVVFGGFASHSVAARIDDAKPVLIV
                     SADAGARGGKIIPYKKLLDDAISQAQHQPRHVLLVDRGLAKMARVSGRDVDFASLRHQ
                     HIGARVPVAWLESNETSCILYTSGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGSV
                     FFCASDIGWVVGHSYIVYAPLLAGMATIVYEGLPTWPDCGVWWKIVEKYQVSRMFSAP
                     TAIRVLKKFPTAEIRKHDLSSLEVLYLAGEPLDEPTASWVSNTLDVPVIDNYWQTESG
                     WPIMAIARGLDDRPTRLGSPGVPMYGYNVQLLNEVTGEPCGVNEKGMLVVEGPLPPGC
                     IQTIWGDDGRFVKTYWSLFSRPVYATFDWGIRDADGYHFILGRTDDVINVAGHRLGTR
                     EIEESISSHPGVAEVAVVGVKDALKGQVAVAFVIPKESDSLEDRDVAHSQEKAIMALV
                     DSQIGNFGRPAHVWFVSQLPKTRSGKMLRRTIQAICEGRDPGDLTTIDDPASLDQIRQ
                     AMEE"
     gene            complement(30800..32251)
                     /gene="prpD"
                     /locus_tag="RN951_001640"
     CDS             complement(30800..32251)
                     /gene="prpD"
                     /locus_tag="RN951_001640"
                     /EC_number="4.2.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate dehydratase"
                     /protein_id="HDX2526653.1"
                     /translation="MSAQINNIRPEFDREIVDIVDYVMNYEISSKVAYDTAHYCLLDT
                     LGCGLEALEYPACKKLLGPIVPGTVVPNGVRVPGTQFQLDPVQAAFNIGAMIRWLDFN
                     DTWLAAEWGHPSDNLGGILATADWLSRNAVASGKVPLTMKQVLTAMIKAHEIQGCIAL
                     ENSFNRVGLDHVLLVKVASTAVVAEMLGLTREEILNAVSLAWVDGQSLRTYRHAPNTG
                     TRKSWAAGDATSRAVRLALMAKTGEMGYPSALTAPVWGFYDVSFKGESFRFQRPYGSY
                     VMENVLFKISFPAEFHSQTAVEAAMTLYEQMQAAGKTAADIEKVTIRTHEACIRIIDK
                     KGPLNNPADRDHCIQYMVAIPLLFGRLTAADYEDNVAQDKRIDALREKINCFEDPAFT
                     ADYHDPEKRAIANAITLEFTDGTRFEEVVVEYPIGHARRRQDGIPKLVDKFKINLARQ
                     FPTRQQQRILEVSLDRARLEQMPVNEYLDLYVI"
     gene            complement(32285..33454)
                     /gene="prpC"
                     /locus_tag="RN951_001641"
     CDS             complement(32285..33454)
                     /gene="prpC"
                     /locus_tag="RN951_001641"
                     /EC_number="2.3.3.16"
                     /EC_number="2.3.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate synthase"
                     /protein_id="HDX2526654.1"
                     /translation="MSDTTILQNSTHVIKPKKSVALSGVPAGNTALCTVGKSGNDLHY
                     RGYDILDLAKHCEFEEVAHLLIHGKLPTRDELAAYKTKLKALRGLPANVRTVLEALPA
                     ASHPMDVMRTGVSALGCTLPEKEGHTVSGARDIADKLLASLSSILLYWYHYSHNGERI
                     QPETDDDSIGGHFLHLLHGEKPSQSWEKAMHISLVLYAEHEFNASTFTSRVIAGTGSD
                     MYSAIIGAIGALRGPKHGGANEVSLEIQQRYETPDEAEADIRKRVENKEVVIGFGHPV
                     YTIADPRHQVIKRVAKQLSQEGGSLKMYNIADRLETVMWESKKMFPNLDWFSAVSYNM
                     MGVPTEMFTPLFVIARVTGWAAHIIEQRQDNKIIRPSANYVGPEDRPFVALDKRQ"
     gene            complement(33801..34691)
                     /gene="prpB"
                     /locus_tag="RN951_001642"
     CDS             complement(33801..34691)
                     /gene="prpB"
                     /locus_tag="RN951_001642"
                     /EC_number="4.1.3.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylisocitrate lyase"
                     /protein_id="HDX2526655.1"
                     /translation="MSLHSPGKAFRAALTKENPLQIVGTINANHALLAQRAGYQAIYL
                     SGGGVAAGSLGLPDLGISTLDDVLTDIRRITDVCSLPLLVDADIGFGSSAFNVARTVK
                     SMIKAGAAGLHIEDQVGAKRCGHRPNKAIVSKEEMVDRIRAAVDAKTDPDFVIMARTD
                     ALAVEGLDAAIERAQAYVEAGAEMLFPEAITELAMYRQFADAVQVPILANITEFGATP
                     LFTTDELRSAHVAMALYPLSAFRAMNRAAEHVYNVLRQEGTQKSVIDTMQTRNELYES
                     INYYQYEEKLDNLFARSQVK"
     gene            34930..36516
                     /gene="prpR"
                     /locus_tag="RN951_001643"
     CDS             34930..36516
                     /gene="prpR"
                     /locus_tag="RN951_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate catabolism operon regulatory protein
                     PrpR"
                     /protein_id="HDX2526656.1"
                     /translation="MAHPPRLNDDKPVIWTVSVTRLFELFRDISLEFDHLANITPIQL
                     GFEKAVTYIRKKLANERCDAIIAAGSNGAYLKSRLSVPVILIKPSGYDVLQALAKAGK
                     LTSSIGVVTYQETIPALVAFQKTFNLRLDQRSYITEEDARGQINELKANGTEAVVGAG
                     LITDLAEEAGMTGIFIYSAATVRQAFSDALDMTRMSLRHNTHDATRNALRTRYVLGDM
                     LGQSPQMEQVRQTILLYARSSAAVLIEGETGTGKELAAQAIHREYFARHDARQGKKSH
                     PFVAVNCGAIAESLLEAELFGYEEGAFTGSRRGGRAGLFEIAHGGTLFLDEIGEMPLP
                     LQTRLLRVLEEKEVTRVGGHQPVPVDVRVISATHCNLEEDMQQGRFRRDLFYRLSILR
                     LQLPPLRERVADILPLAESFLKVSLAALSAPFSAALRQGLQASETVLLHYDWPGNIRE
                     LRNMMERLALFLSVEPTPDLTPQFMQLLLPELARESAKTPAPRLLTPQQALEKFNGDK
                     TAAANYLGISRTTFWRRLKS"
     gene            complement(36614..36889)
                     /locus_tag="RN951_001644"
     CDS             complement(36614..36889)
                     /locus_tag="RN951_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDX2526657.1"
                     /translation="MKIISKMLVGALALAVTNVYAAELMTKAEFEKVESQYEKIGDIS
                     TSNEMSTADAKEDLIKKADEKGADVLVLTSGQTDNKIHGTANIYKKK"
     gene            37036..37707
                     /locus_tag="RN951_001645"
     CDS             37036..37707
                     /locus_tag="RN951_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysE family transporter"
                     /protein_id="HDX2526658.1"
                     /translation="MMQLVHLFMDEITMDPLHAVYLTVGLFVITFFNPGANLFVVVQT
                     SLASGRRAGVLTGLGVALGDAFYSGLGLFGLATLITQCEEIFSLIRIVGGAYLLWFAW
                     CSMRRQSTPQMSTLQQPISAPWYVFFRRGLITDLSNPQTVLFFISIFSVTLNAETPTW
                     ARLMAWAGIVLASIIWRVFLSQAFSLPAVRRAYGRMQRVASRVIGAIIGVFALRLIYE
                     GVTQR"
     gene            complement(37724..37969)
                     /locus_tag="RN951_001646"
     CDS             complement(37724..37969)
                     /locus_tag="RN951_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414861.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526659.1"
                     /translation="MAVQLFKTLLNQIPLLSSLQSGTLPLFGYSGWGRPMKKAHTGES
                     GLKWEAKDSSKLIGNKDHALRGLSSPMAVIRQIRLIT"
     gene            complement(38382..39197)
                     /locus_tag="RN951_001647"
     CDS             complement(38382..39197)
                     /locus_tag="RN951_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526660.1"
                     /translation="MISLKAPHNNLMPYTQQSILNTVKNNQLPEDIKSSLVSCVDIFK
                     VLIKQYYDYPYDCRDDLVDDDKLIHLMAAVRDCEWSDDNALTINVQFNDFPGFYDWMD
                     YPDHPVKFVFRILENQKGTVWVYDQDDAFLDIKANVQAGRFTGLKKLVQFIDSVRTDC
                     KCILLEYHMPLLRIFPKGKECMHVEKWLREMSSIPETDAPIKQALAHGLLLHLKNIYP
                     VFPESLVMLLLSVLDVKTYRDDARLNEWISNRVQELGDRYYPVNKHVKIRYTL"
     gene            complement(39440..40489)
                     /gene="yahK"
                     /locus_tag="RN951_001648"
     CDS             complement(39440..40489)
                     /gene="yahK"
                     /locus_tag="RN951_001648"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent aldehyde reductase YahK"
                     /protein_id="HDX2526661.1"
                     /translation="MKIKAVGAYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDL
                     HQVRSEWAGTVYPCVPGHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDG
                     LENYCDHMTGTYNSPTPDEPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAG
                     ITTYSPLRHWQAGPGKKVGVVGIGGLGHMGIKLAHAMGAHVVAFTTSEAKREAAKALG
                     ADEVVNSRNADEMAAHLKSFDFILNTVAAPHNLDDFTTLLKRDGTMTLVGAPATPHKS
                     PEVFNLIMKRRAIAGSMIGGIPETQEMLDFCAEHGIVADIEMIRADQINEAYERMLRG
                     DVKYRFVIDNRTLTD"
     gene            complement(40866..42248)
                     /locus_tag="RN951_001649"
     CDS             complement(40866..42248)
                     /locus_tag="RN951_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDX2526662.1"
                     /translation="MKESNSRREFLSQSGKMVTAAALFGTSVPLAHAAVAGTLNCEAN
                     NTMKITDPHYYLDNVLLETGFDYENGVAVQTRTARQTVEIQDGKIVALRENKLHPDAT
                     LPHYDAGGKLMLPTTRDMHIHLDKTFYGGPWRSLNRPAGTTIQDMIKLEQKMLPELQP
                     YTQERAEKLIDLLQSKGTTIARSHCNIEPVSGLKNLQNLQAVLARRQAGFECEIVAFP
                     QHGLLLSKSEPLMREAMQAGAHYVGGLDPTSVDGAMEKSLDTMFQIALDYDKGVDIHL
                     HETTPAGVAAINYMVETVEKTPQLKGKLTISHAFALATLNEQQVDELANRMVVQQISI
                     ASTVPIGTLHMPLKQLHDKGVKVMTGTGSVIDHWSPYGLGDMLEKANLYAQLYIRPNE
                     QNLSRSLFLATGDVLPLNEKGERVWPKAQDDASFVLVDASCSAEAVARISPRTATFHK
                     GQLVGGSVAG"
     gene            complement(42258..43208)
                     /locus_tag="RN951_001650"
     CDS             complement(42258..43208)
                     /locus_tag="RN951_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase family protein"
                     /protein_id="HDX2526663.1"
                     /translation="MKELVVVAIGGNSIIKDNASQSIEHQAEAVKAVADTVLEMLASD
                     YDIVLTHGNGPQVGLDLRRAEIAHKREGLPLTPLANCVADTQGGIGYLIQQALNNRLA
                     RHGEKKAVTVVTQVEVDKNDPGFAHPTKPIGAFFSDSQRDELQKANPDWCFVEDAGRG
                     YRRVVASPEPKRIVEAPAIKALIQQGFVVIGAGGGGIPVVRTDAGDYQSVDAVIDKDL
                     STALLAREIHADILVITTGVEKVCIHFGKPQQQALDRVDIATMTRYMQEGHFPPGSML
                     PKIIASLTFLEQGGKEVIITTPECLPAALRGETGTHIIKT"
     gene            complement(43284..43580)
                     /locus_tag="RN951_001651"
     CDS             complement(43284..43580)
                     /locus_tag="RN951_001651"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526664.1"
                     /translation="MAQESVGLISVAHQAFVTIAGCGVNALSGLRMAQESVGLISVAH
                     QAFATTAGCGVDALSGLRVARESVGLISVAHQAFVTIAGCGVNALSGLRVAREL"
     gene            complement(43630..45048)
                     /locus_tag="RN951_001652"
     CDS             complement(43630..45048)
                     /locus_tag="RN951_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HDX2526665.1"
                     /translation="MSQSLFSQPLNVINVGIAMFSDDLKKQHVEVTQLDWTPPGQGNM
                     QVVQALDNIADSPLADKIAAANQQALERIIQSHPVLIGFDQAINVVPGMTAKTILHAG
                     PPITWEKMCGAMKGAVTGALVFEGLAKDLDEAAELAASGEITFSPCHEHDCVGSMAGV
                     TSASMFMHIVKNKTYGNIAYTNMSEQMVKILRMGANDQSVIDRLNWMRDVQGPILRDA
                     MKIIGEIDLRLMLAQALHMGDECHNRNNAGTTLLIQALTPGIIQAGYSVEQQREVFEF
                     VASSDYFSGPTWMAMCKAAMDAAHGIEYSTVVTTMARNGVEFGLRVSGLPGQWFTGPA
                     QQVIGPMFAGYKPEDSGLDIGDSAITETYGIGGFAMATAPAIVALVGGTVEEAIDFSR
                     QMREITLGENPNVTIPLLGFMGVPSAIDITRVGSSGILPVINTAIAHKDAGVGMIGAG
                     IVHPPFACFEKAILGWCERYGV"
     gene            complement(45048..46595)
                     /gene="fdrA"
                     /locus_tag="RN951_001653"
     CDS             complement(45048..46595)
                     /gene="fdrA"
                     /locus_tag="RN951_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HDX2526666.1"
                     /translation="MSVKIVIKPNTYFDSVSLMSISTRANKLDGVEQAFVAMATEMNK
                     GVLKNLGLLTPELEQAKNGDLMIVINGKSGADNEQLLVEIEELFNTKAQSGSHEARYA
                     TIGSAKKHIPESNLAVISVNGLFAAREARQALQNDLNVMLFSDNVSVEDELALKQLAH
                     EKGLLMMGPDCGTAIINGAALCFGNAVRRGNIGIVGASGTGSQELSVRIHEFGGGVSQ
                     LIGTGGRDLSEKIGGLMMLDAIGMLENDPQTEIIALISKPPAPAVARKVLERARACRK
                     PVVVCFLDRGETPVDEQGLQFARGTKEAALKAVMLSGVKQENLDLHTLNQPLIADVRA
                     RLQPQQKYIRGLFCGGTLCDETMFAVMEKHGDVYSNIQPDPEFRLKDINRSIKHTFLD
                     FGDDDFTNGKPHPMIDPTNRISRLIEEARDPEVAVIVMDFVLGFGSHEDPVGSTIETI
                     KEAKAIAAAEGRELIILAYVLGTDLDTPSLEQQSQMLLDAGVILASSSTNTGLLAREF
                     ICKGEEA"
     gene            complement(46585..47448)
                     /locus_tag="RN951_001654"
     CDS             complement(46585..47448)
                     /locus_tag="RN951_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HDX2526667.1"
                     /translation="MWALTADADFLAQRGQGQVEQVFARAVNIALPARQQLLTLLCEE
                     YDNAPNSCRLALTHFDDLFRHGDKVQFDDQGITVGQHLHIEMSRCRRWLSPTLQMTAV
                     NFHLIAWLQWHDIIHQHLGENETLFNYRGDNPFYQALNKELHIKRRAVIQAVNDKQNI
                     ASAVASMMGLGIGLTPSADDYLTGLALILFIPGHPAEKYKEEFYLGLQRGKNNTTLLS
                     AITLEAALQQRCRENIHRFIHNIIYDIPENATQAIEKIKHIGSSSGCDMLYGMADGCA
                     LSQTYGGNYVS"
     gene            complement(47488..48093)
                     /locus_tag="RN951_001655"
     CDS             complement(47488..48093)
                     /locus_tag="RN951_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ankyrin repeat domain-containing protein"
                     /protein_id="HDX2526668.1"
                     /translation="MSIKNLPADYLLAAQQGDIDKVKTCLALGVDINTCDRQGKTAIT
                     LASLYQQYACVQALIDAGADINKQDHTCLNPFLISCLNDDLTLLRIILPAKPDLNCVT
                     RFGGVGLTPACEKGHLSIVKELLAHTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIV
                     QLLLEHGASPHLTDKYGKTPLELARERGFEEIAQLLIAAGA"
     gene            48351..48848
                     /locus_tag="RN951_001656"
     CDS             48351..48848
                     /locus_tag="RN951_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HDX2526669.1"
                     /translation="MNGLTATGVTVGICAGLWQLVSSHVGLSQGWELLGTIGFVAFCS
                     FYAAGGGKSGFIRSLAVNYSGMVWAFFAALTAGWLASVSGLSAFWASVITTVPFSAVV
                     VWQGRFWLLSFIPGGFLGMTLFFASGMNWTVTLLGFLAGNCVGVISEYGGQKLSEATT
                     KRDGY"
     gene            48940..49872
                     /locus_tag="RN951_001657"
     CDS             48940..49872
                     /locus_tag="RN951_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX2526670.1"
                     /translation="MNSIFTEENLLAFTTAARFGSFSKAAEELGLTTSAISYTIKRME
                     TGLDVVLFTRSTRSIELTESGRYFFRKATDLLNDFYAIKRSIDTISQGIEARVRICIN
                     QLLYTPKHTARLLQVLKKQFPTCQITVTTEVYNGVWDAIINNQANIAIGAPDTLLDGG
                     GIDYTEIGAIRWAFAIAPDHPLAFVPEPIAESQLRLYPNIMVEDTAHTINKKVGWLLH
                     GQESILVPDFNTKCQCQILGEGIGFLPDYMVREAMTQSLLVTRQIHNPRQDSRMLLAT
                     QHSATGQVTQWIKKQFAPNGILTGIYQDLLHREN"
     gene            complement(49914..51002)
                     /gene="pdeL"
                     /locus_tag="RN951_001658"
     CDS             complement(49914..51002)
                     /gene="pdeL"
                     /locus_tag="RN951_001658"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator/c-di-GMP
                     phosphodiesterase PdeL"
                     /protein_id="HDX2526671.1"
                     /translation="MNSCDFRVFLQEFGTTVHLSLPGSVSEKERLLLKLLMQGMSVTE
                     ISQYRNRSAKTISHQKKQLFEKLGIQSDITFWRDIFFQYNPEIISATGSNSHRYINDN
                     HYHHIVTPEAISLALENHEFKPWIQPVFCAQTGVLTGCEVLVRWEHPQTGIIPPDQFI
                     PLAESSGLIVIMTRQLMKQTADILMPVKHLLPDNFHIGINVSAGCFLAAGFEKECLNL
                     VNKLGNDKIKLVLELTERNPIPVTPEARAIFDSLHQHNITFALDDFGTGYATYRYLQA
                     FPVDFIKIDKSFVQMASVDEISGHIVDNIVELARKPGLSIVAEGVETQEQADLMIGKG
                     VHFLQGYLYSPPVPGNKFISEWVMKAGG"
BASE COUNT        12086 a        13948 c        13170 g        12297 t
ORIGIN      
        1 caaacactta acatatgaat tgcatagaaa cattacccag tcgaacccac gggtctgaaa
       61 gcccttgctt ttcagttatt agcaacattt aacatttata aattaacatc tggctgcgcc
      121 agagattacg tctctgagtg catcgttgtg cttgtagtat aataaataaa atggagtgtc
      181 attaagtgga taaggtttta gattcagccc tcctttcttc ggcaaataaa agaaagggta
      241 tccttgctat tggcgcacat cctgacgata tagaattagg ctgtggcgca tcgcttgctc
      301 gtcttgcgca aaaaggaatt tatatcgcag ccgtggtgat gactaccggc aactctggca
      361 cagatggaat aatcgatcgc catgaagaat cgcgcaacgc cctaaagata ttagggtgcc
      421 accaaactat tcatcttaat tttgctgaca cccgcgctca tttacagctc aatgatatga
      481 tttccgccct ggaagacatc attaaaaatc aaattccttc tgatgttgaa atcatgcggg
      541 tatataccat gcatgatgcc gaccgccatc aggatcatct tgctgtttat caagcttcaa
      601 tggttgcctg ccgaactatt ccgcaaattc tcggctacga aaccccaagt acctggcttt
      661 catttatgcc tcaggttttt gaatccgtta aagaagaata tttcacagtc aaacttgctg
      721 cattaaaaaa acataaaagc caggaacgac gcgattatat gcgtcatgat cgcctgcgtg
      781 cagttgcaca atttcgcgga caacaggtca atagcgatct gggtgaaggc tttgtaattc
      841 ataaaatgat tctttgagca aattgcatga aaacctggat atttatctgt atgtccatag
      901 caatgttgct atggttttta agtacgctaa gacgtaaacc cagtcaaaag aaaggctgta
      961 ttgacgccat tatacctgcg tataacgaag gcccgtgtct ggcgcagtca ctggataatc
     1021 tactgcgtaa cccttatttt tgccgggtaa tttgcgttaa cgacggctcc acggacaata
     1081 ccgaagcggt catggcggaa gtcaaacgca aatggggcga ccgctttgtt gccgtcacgc
     1141 aaaaaaatac cggtaaaggt ggtgcgctga tgaatggcct caattacgcc acctgcgacc
     1201 aggttttttt aagtgatgcc gacacctatg ttccgcccga tcaagacgga atgggctata
     1261 tgctggcaga aattgagcgc ggtgccgatg ccgtaggcgg cattccctct actgcgttga
     1321 aaggcgcggg tctgttaccg cacatccgcg cgaccgtaaa gttgccgatg attgttatga
     1381 agcgcacgct acagcagctc ctgggtggcg caccgtttat tatcagcggt gcctgcggga
     1441 tgttccgtac tgatgtattg cgtaagttcg gtttctcgga tcgtactaaa gtcgaagacc
     1501 ttgatctcac ctggacattg gtggcaaacg gctaccgtat tcggcaggcg aatcgctgca
     1561 tcgtataccc acaggaatgc aacagcccgc gtgaggagtg gcgtcgctgg cggcgttgga
     1621 ttgtgggata cgcggtctgt atgcgcctgc ataaaagact tttatttagc cgcttcggta
     1681 tcttcagtat atttcctatg ctgttggttg tgctttatgg cgttgggatt tatctcacta
     1741 cctggtttaa tgaattcatc accaccgggc cgcatggagt ggtgttggca atgtttccgc
     1801 ttatctgggt cggcgtagtt tgtgttattg gtgcttttag cgcctggttt catcgttgct
     1861 ggttgttggt gcctttagcg ccgctttccg ttgtgtatgt attattagct tatgccatct
     1921 ggattattta tggacttatt gcctttttta ctggacgcga acctcagcgc gacaaaccca
     1981 cccgctattc cgcactggtg gaagcgtcaa ccgcttattc ccaaccttct gtcacaggaa
     2041 ctgaaaaact atctgaagct taatgttaaa gagaaaaata ttcagattgc agaccaggta
     2101 attattgatg aaactgcagg tgaagttgtt atcggcgcga atacccgtat ttgtcatggt
     2161 gccgttattc agggtccggt agtgattggc gcaaactgcc tgataggtaa ttatgcgttt
     2221 attcgtcctg gcacaataat cagcaatggc gtaaaaattg gttttgccac cgagattaaa
     2281 aatgcggtta ttgaagcgga agcaacgatt ggtccgcaat gttttattgc cgactcggta
     2341 gttgcaaacc aggcatattt aggcgcacaa gtacgtacca gtaatcatcg tctggatgaa
     2401 cagcccgtgt ctgttcgaac tccagaggga attatcgcta ccggatgcga taaattaggt
     2461 tgttatatcg ggcagcgttc acgccttggc gtacaagtta ttattttgcc tgggcgaatt
     2521 atttccccga acacgcaact tggcccgcgc gtgattgtag aacgtaattt acctaccgga
     2581 acttattcac tccgacaaga acttatccgt acaggagatt aaaatgataa aacggacgtt
     2641 attagcggcg gccattttta gcgcattgcc cgcttatgcc gggttaactt ccattaccgc
     2701 gggctacgat tttaccgatt attctggcga tcatggcaac cgtaatttag cgtatgctga
     2761 actggtggcg aaagttgaaa acgcaacgct gctttttaat ctttcccagg ggcgtcgtga
     2821 ttatgaaact gaacatttca atgccactcg cggtcagggt gcggtctggt ataaatggaa
     2881 taactggctg acaacccgaa cgggtattgc ctttgcggat aatacgccgg tctttgcccg
     2941 ccaggatttt cgtcaggata ttaacctggc cctgttacca aaaacgcttt tcacgaccgg
     3001 ttatcgctac actaaatatt acgatgatgt cgaagtcgat gcctggcaag gcggcgtatc
     3061 actctatact ggcccggtga tcaccagcta ccgctatacc cattatgact ccagcgatgc
     3121 aggtggtagt tatagcaata tgatttccgt gcgtctgaat gacccgcgcg gcactggtta
     3181 tacgcaacta tggctaagcc gcggaacagg tgcttacacc tatgactgga cgccagaaac
     3241 acgctacggc agcatgaaga gcgtcagtct gcaacgtatt caaccgctga ctgagcaact
     3301 taatctcggg ctgacggcag gtaaagtgtg gtacgacacc ccaaccgatg attttaacgg
     3361 tctgcaactt gcagcccgtc tgacctggaa attctgattc cttctgccgc ccgctatccg
     3421 gggcggcctt ccctgccgat tagccccccc ccctttcctc tttgttttcc gaccacattc
     3481 accggataaa ttttattctc cagtgttata tactataggg gggtatgcat tgacatatag
     3541 aatacccccc tatagtatat tgcatgcaga tgatgaggtg cgaaatgccc agtactccgg
     3601 aagagaagaa aaaggtcctt actcgagttc gtcgtattcg ggggcagatt gatgctctgg
     3661 aacggtcgct ggagggtgat gccgaatgcc gtgccatact ccaacagatc gctgccgttc
     3721 ggggcgcggc taatgggctg atggcagaag tgcttgaaag ccatatccgg gaaacgtttg
     3781 accgaaatga ctgctacagc cgcgaagtca gccaatccgt tgacgacact attgaactgg
     3841 ttcgtgccta tcttaaatag ctgaatctat taccatattg aggaagagcg agagatgaaa
     3901 tcacgtgctg ccgttgcatt tgctcccggt aaaccgctgg aaatcgttga aattgacgtt
     3961 gcaccaccga aaaaaggtga agtgctaatt aaagtcaccc ataccggcgt ttgccatacc
     4021 gacgcattta ccctctccgg cgatgacccg gaaggtgtat tcccggtggt tctcggtcac
     4081 gaaggggccg gcgttgtggt tgaagtcggt gaaggcgtaa ccagcgtcaa acctggcgac
     4141 catgtgatcc cgctttacac cgcggagtgc ggcgagtgtg agttctgtcg ttctggcaaa
     4201 actaacctct gtgttgcggt tcgcgaaacc cagggtaaag gcctgatgcc agacggcacc
     4261 acccgttttt cttacaacgg gcagccgctt tatcactaca tggggtgctc tacattcagt
     4321 gaatacaccg tagtcgcgga agtgtctctg gcaaaaatta atccagaagc aaaccatgaa
     4381 cacgtctgcc tgctgggctg tggcgtgacc accggtattg gcgcggtaca caacacagct
     4441 aaagtccagc caggtgattc tgttgccgtg tttggtcttg gcgcgattgg tctggcagtg
     4501 gttcagggcg cgcgtcaggc gaaagcgggt cggattatcg ctatcgatac caacccgaag
     4561 aaattcgatc tggcgcgtcg cttcggtgct accgactgca ttaacccgaa tgactacgac
     4621 aaaccgataa aagatgtcct gttggatatc aacaaatggg gtatcgacca tacctttgaa
     4681 tgcatcggta acgtcaacgt gatgcgtgcg gcgctggaaa gtgcgcaccg cggctggggt
     4741 cagtcggtga tcatcggggt cgcgggtgcc ggtcaggaaa tctccacccg tccattccag
     4801 ttggtcactg gtcgcgtatg gaaaggttcc gcgtttggcg gcgtgaaagg tcgttcccag
     4861 ttaccgggca tggttgaaga tgcgatgaaa ggtgatatcg atctggaacc gtttgtcacg
     4921 cataccatga gcctggatga aattaatgac gccttcgacc tgatgcatga aggcaaatcc
     4981 attcgaaccg taattcgtta ctgatttccc gcaggtttac cccgtccact tcaggcgggg
     5041 gttcttaata ctctccccgg gcagccgtcc gggggattaa ccctgagata atgactgatg
     5101 gaactcattg aaaaacatgt cagctttggc ggctggcaaa atgtgtatcg gcattattcc
     5161 caatcactga aatgtgaaat gaatgtcggc gtctatctcc caccaaaagc cgcgaatgaa
     5221 aaattgccgg tgctgtactg gctttcaggc ctgacctgca acgagcagaa tttcattact
     5281 aaatcgggga tgcagcgtta cgcggctgag cacaacatta ttgttgttgc gccggacacc
     5341 agtccgcgag gcagtcatgt cgcagatgct gaccgttacg atctcgggca aggtgccggg
     5401 ttttacctga acgcgacgca agcgccgtgg aatgaacatt acaaaatgta tgactatatc
     5461 cgcaacgagc tgccggattt agtgatgcat cattttccgg caacggccaa aaagtctatc
     5521 tctggtcatt ctatgggcgg gctgggcgcg ctggtgctgg cgttacgtaa cccagatgaa
     5581 tatgtcagcg tctcggcgtt ttcgcccatt gtctccccat cgcaagtgcc gtggggacag
     5641 caagcctttg ctgcatatct tgctgaaaat aaagatgcct ggttggatta cgacccggtg
     5701 agtcttattt cacaaggtca acgcgttgcg gaaatcatgg ttgatcaggg gttgagtgat
     5761 gatttttacg cagaacagct gcggactcca aatcttgaaa agatctgcca ggagatgaat
     5821 atcaagacgt taatccgtta tcacgagggt tatgatcaca gctattattt tgtctccagt
     5881 tttattggcg agcatattgc ctaccacgcc aataaactga atatgcgttg ataatagcac
     5941 gactgccgga tgcggcgtga acgccttatc cggcctacac ttcgcccgta agccgtaggc
     6001 ctgataagac gcgcaaagcg tcgcatcagg catggcgcac gactgccgga tgcggcgtga
     6061 acgccttatc cggtctacac ttcgcccata aaccgtaggc ctgataagac gcgcatagcg
     6121 tcgcatcagg catctgcgca cgacttatct atgtttacca catcaaatca tcaggcactt
     6181 tgaagtcggc atacgggtcg tcttcatcct gctcttcggc gctgagcgcg ctgtgcaaca
     6241 ctatactgct ggcatcgcgc tgagcaattt tatcggcaac gctggcggga ataatggcgt
     6301 attcaccttc gctattgtta tcgaccaaca agcgggcaat cgccagacga ccattaatca
     6361 actgcgcctg tgtgagctta tcgacaaaaa tcttcttaat cagattgccg tcagtgaagt
     6421 taaaaccaat atcgccattg gcaatggtga ttcggttcat ttcaataagc tgcttcacct
     6481 gagctttata ttctttcgcc aacgccgctt gtttttgctg ttcgctaagc tgtttatcac
     6541 gctcaagctg tgccttttta ttttcttcta ccgccgcccg agcttcacgc gcctgaacgc
     6601 gcgatttttt cgccgttctc tccaccttcg ccgctttttt gctggtgact aatcctgctt
     6661 tgagcaactg ctcttgtaag gtaagttttg ccatctttgt ttccaaaccc gctgaataat
     6721 ttttagcgag tatacctgta aacgccgtag gtgtattggg gtgaagtccc tttcgcccct
     6781 gcctaataag gcacgtcagg catcggcgca cggctgtatt cgtgatctcc ggctcatcaa
     6841 aataaacacc gccaacccag caacaagaat acccggtgca gaagcggcca ttacgccgac
     6901 cgtgccagtg cctaatgcca gcattttccc ggccagtaac ggaccgctca tagcccccag
     6961 acgccctacc gccacggctg ttcccacacc tgttgcgcgg atctgcgaac tgtaaaacaa
     7021 cggtgccagg gcatacaaaa cgctttgccc acctgtcgca aacaaccccg cgacaaatcc
     7081 cgccagcaac ataccgttaa atgacgacac cgttccaagc gccagcagcg aagctaacat
     7141 gccgctataa atcagtagcg acatggttac tggacgcagc ttatccatca atgcgcccaa
     7201 cattaacgtc ccgcttgccg cccccatttg cagggcaaac atcacccctg ccgcctgcga
     7261 tggctggaat ccttgctcca ccaaaagtag cggtagccag ttgatcaaca tgtagaccac
     7321 cagcagagtg aagaaataac acaaccacag cagcagcgtc gcggttgccg tttctggcgc
     7381 aaataaggca cgcagtggtg gcgcagactg tttttcgcca gcgaaaaccg ccgactccgg
     7441 cagccagcgc attaatagcg gcaccagaat caacggcacc acaccaccta cccaaaacac
     7501 cgtttgccat gctaagtttg cccccgcgaa acccagtgtc gccgccagcg ccgcgccaat
     7561 gggaacaccg caatacatca ggctcactgc cgtcccacga aaacgtggac ccgcggcttc
     7621 agacgtcagg gcgataagat tcggcaacgc cgcccccagc ccgacaccgg tcatcagccg
     7681 cgcaaagacc agtgagggga aatcccaggc aatcgccgtt gccagtgaga acaaaccaaa
     7741 cagcgcaact gagccaatca aaatgcgctt gcgaccataa cggtccgcca gcattccgcc
     7801 aaccaacgcg ccgggtagca aaccgagtat tccggcgcta aatatccagc ccatttgcat
     7861 tttatcgagt gcgaaagcct gggcgatgcc acccgccgca atgccagccg cctgaagatc
     7921 cagcccttcc atcagagcga ccaaaaaaca aagcccgatg gtcagcatca ggcgggatga
     7981 agatgatgaa ggggtacgag tcgacataag atgaacctcg ttgcgagtgc aggtgaatcg
     8041 cgactgatac attgccagcc gcgtaatcag aactatttaa tgactgccta cgggcgaaat
     8101 gtaggccgga caagacgttt atcgcatccg gcagtcgtgt gcagatgcct gatgcgacgc
     8161 taacgcgtct tatcaggcct acaaattccc gcgccatccg taggccggat aaggcgttta
     8221 cgccgcatcc ggcagtcgtg cgcagatgcc tgatgcgacg ctaacgcgtc ttatcaggcc
     8281 tacaaattct cgcgccaccc gtaggccgga taaggcgttc acgccgcatc cggcagtcgt
     8341 gcgcagatgc ctgatgcgac gctaacgcgt cttatcaggc ctacaaattc ccgcgccatc
     8401 cgtaggccgg ataaggcgtt cacgccgcat ccggcagtcg tgcgcagatg cctgatgcga
     8461 cgctaacgcg tcttatcaga cctacaaatt ctcacgccat ccgtaggccg gataaggcgt
     8521 tcacgccgca tccggcagtc gtgctgggat gggcatacaa aatgcacgtt ctcggcagtc
     8581 atcattattt gttgttgcgc agatccagcg ccacgtcaac gatcatatcc tcctggccgc
     8641 caaccatccg gcgtttgccc agctcaacga gaatatccac cgcacttaag ccataacgcg
     8701 ccgccgccgt ttcacagtga cgcaggaagc tcgagtaaac accagcgtat cccagcgcca
     8761 gcgtttcgcg atcgactcgt accggtcgat cctgcaacgg acgcaccagg tcgtcggcgg
     8821 catccattaa cgcatagaga tcggtcccat gctgccagcc cagtttatcc gcggcggcaa
     8881 taaacacttc cagcggtgcg ttacctgcgc ccgcgcccat tcccgcgagg ctggcgtcga
     8941 ttcggtcgca gccctcttcc accgccgcga tagagttcgc cacgccaaga ctcaggttat
     9001 ggtgagcgtg catgccagtt tgcgtttctg gtttcagctc tgctttcagg gcgcggaaac
     9061 ggtcacggat atcgctcatg ttcatcgcac cgccagaatc caccacataa atacaggtcg
     9121 caccgtagcc ttccatcagc tttgcctgct tggcgagatt ctccggcgtg gtcatatggc
     9181 tcatcatcag aaaaccaacg gtgtccattc cgagctcgcg ggcatactga atatgctggg
     9241 cggaaacatc agcttcggta cagtgcgttg ccacacgaac cacccgcgcg ccagcctgcc
     9301 aggcattttt cagatcgtga atagtgccga ttcctggcag caacaacgtc gcgattttgg
     9361 cgtgcttcac cacatccgcc gccgcttcaa tccattcaag gtcgctatgt gcgccgaaac
     9421 catagttaaa gctggaacct tgcaaaccgt cgccgtgggc cacttcaatc gaatccacgc
     9481 gggcatcgtc cagtgctttg gcaatctggc gaacgttttc cagcgaatac tgatgacgaa
     9541 tggcgtgcat accgtcacgc aatgtgacgt ccgagatata aagtttttta ccgttcatgc
     9601 cgcttctcct gccttgcgcg ccagtgactg ggccattttt tccgctgtcg ccagcgcact
     9661 ggaagtcata atgtcgaggt tgcccgcata ggcaggcaga taatgcgctg cgccttcgac
     9721 ttccagccag accgctgttt tcagtccgga gaattgcccc acgcccggta aattgaccgg
     9781 tttatcctgc gggataactt caaactgcac gcgctgtttc aggcgataac ccggtacgta
     9841 agcctgcacc gcctcagcca tttcattgat tgaggcttcg atatcatctt gtgaagcttc
     9901 gtcgctcaat acatacaccg tgtcacgcat catcaacggt ggctctgctg ggttaagcac
     9961 aataatcgcc ttcccttttg ccgcgccgcc caccacttca atggctcggg aagtggtttc
    10021 cgtaaattca tcgatattgg cacgcgtgcc aggtccggca gatttactgg cgatagaagc
    10081 gataatttcg gcgtaatgaa cacgcgccac gcgtgaaact gccgccacca ttggaatggt
    10141 ggcctggccg ccgcaggtga ccatgttgac gttcagttga tcgacgttcg cctcgaggtt
    10201 aaccaccggc acgcagtaag ggccgatggc agcaggcgtc aggtcaatta agcgaatatc
    10261 cggtttcgct tcgcgtaaag cggcatcgtt tttcacatga gcaccggcgc tggtcgcatc
    10321 aaatacaatg tcgatatcag caaattcagg catgttcatc agtccgatca ccccttcatg
    10381 ggtggtggcg acgcccatac gtctggcgcg cgccagaccg tcggactgag gatcaatgcc
    10441 aaccatcacc gccatctcca gatgctgacc gtgacgcaaa attttaatca tcagatcggt
    10501 accaatgttg ccagaaccga taatggcgac tttacgctta ctcatgacag acttcctttt
    10561 ggggctgcgc ttgaaaatgt cgcagcaact gaacctatgc cttcaatatg ggcttcaaaa
    10621 cgatcgcccg cattcaccgc caccatcgga cctaatgccc cggtaagaat gatatctccg
    10681 gtgcgcagcg gttcacccag actggccatt ttgcgtgcca gccagacggc cgcattaagc
    10741 ggatgtccca ggcattcgct gccgcgcccg ctagaaacct cttcgttatt acgcgtcatc
    10801 ttcatggcgc agtttttcag gtctaacccc gccggacgtt gcgccggacc gccgatgaca
    10861 tacaccccac aggaggcgtt atctgccacg gtatcgacaa actgaatcga ccagtcgcga
    10921 atgcggctcc ccaccacttc cagcgccgga agtacccatt caatggcgtt atacaattcg
    10981 tcgaaggtga tatcggttgc gggcaaatcg cggttcaaca ccagtgcgat ctccgcttca
    11041 atgcggggtt gcagaacacg ggaaaaagga atgatttcgt tatcgccata acacatgtcg
    11101 gcaaataacg tcccaaaatc cggttgatca acgcccagtt gttgttgcac tttcggatgt
    11161 gtcaggccca ctttacgccc taccacgcga cgcccctgcg caacgtcatg ttgcacattt
    11221 atgtgctgaa tggcgtaagc cgcttcagcg ttatcgatac caatcagatc gcgcagcggt
    11281 gcaatcgctt cgccctgctc tgcggcgcgg cgtaaatccg ccgccagttg ctcaagagta
    11341 tgcttcgtca tgaccattcc ttaagggcgt gcgaggaaat tcagcaccag ttgattgaaa
    11401 gcgtcggcat gttcccactg cgcccagtga ccacagtcgc ggaagatatg cagttcagaa
    11461 ccggcaatgc cggacagcag acgcagaccc gcatccatcg gcacaaagcg gtcgttgcgc
    11521 ccccagacaa tcagggtttg cgctttgatt tccgccagac gtgggccaaa atccgggaac
    11581 tgtttcggat tagcttccag gctcttaacg aagttttcca ggtgatcgcg gcgcgacagc
    11641 atattattca ggcgcgcttc aaacagggcg tcggtcaaat cgctggtatc aaaaacgaag
    11701 atatccatca tcagcttcag gttttcgata gtcggctgac gataaagctg attcagtcgc
    11761 ttaatacctt cggttggcat cggcgtaaac aaactcatgc cgcccgtacc gccgcccatc
    11821 agcaccagtt tgccgacgcg ctccggccat ttaagggtga acgccacaga actatggccc
    11881 cccatcgagt tgcccagcag gtggattttg gcgatatcca gttgatccac cacgcttttc
    11941 aggattcgtg cattaagatc cgatcgcgaa ccactattaa cgaccgaatc gctcttgccc
    12001 caacccggac aatccagcag gatcacccga tagcccgcct ctaccagcgg atcgatattg
    12061 cggctgaagt tcgcccagcc agtagcaccc gggccggaac catgcagcag gacaacggtt
    12121 tcgtcgcctt gtccgcagtc attaaaatgg atgcgcagcg ttttacccgc ttcttctaca
    12181 ttcagaaaac ggctggtggc ggcttcggtt tgtggctgat aactcatcat cttctcctgc
    12241 atattcagtt ctctgttctg gcgcttaacg agccaaatcc ggcaatccac tccgggattg
    12301 ggcggtaata acgcccttcg ctacgccagt tgccaaacgc agaaatagcg gcaaaagcgg
    12361 cgacccaggt tttgatttca tgtgtcgact ttccggcaat ggcggaaagc tcttcgttac
    12421 tgacggcatc cagttcctgt atgcgtccct gctccagcaa agtcatgaac tggttatccc
    12481 aaatcgggtt gagcggatgc agcgttctct gatcctcaac aaacttctca gcggcgctaa
    12541 tcacccgttg ctgacgcaat tcgcgctcac tggcgggtaa atctttcccg ctccccaaca
    12601 gacggtcgcg catatgggca tcggctttcg ccagttcggg caccggcggc tgatgggaaa
    12661 gcccaccgga acccaggaac agcacgcgtt tattgagagt gctggtgaaa cgtccaatgg
    12721 cttcacccaa catgcgggta cgctggaaac cgggcagcgg cgtggcgaca ccgttgatga
    12781 acacaggcag aactggcacc ttatccagcc caccgagcag gaactccagc ggctgggcga
    12841 acccgtggtc cacctgcata cagtaagaaa cggcaagatc gatcccgctc ttcatgacgg
    12901 catgcgcaca ggcctccgcc agctccacag gcacgggcag ctctcctgcc gcactgccga
    12961 aatcaccaat tgccgtcgct ccaacgccta aacagaacgg tggcatcacg tcatagaaaa
    13021 agccgttgta gtgatctggc gcaaacagca ccaccagttc aggggagaat gccgcaatac
    13081 gctcgcgggc gctggcaatc acgccattga cctcatcgag cacctcttgc gccgggtcga
    13141 cataccccac cagcggcgag tgggaaagac agtgaagata agcgtgcata tcaggctacc
    13201 ttttcgacag aaacgtcggc atcagggcgg gtcagcgtca tcaccgacgc cagtttattc
    13261 agggtcttgc ccagggtttg cggaatggcg gtggcggcaa caaagcgatc cgggcgcatc
    13321 accaccagcg aagcattgtg ttgcgcgaac cagctacgca ggcgaccttg cgtatcgccc
    13381 acgcgtagta cgccgtcgtg gttatcctgt gcggtatgaa tttgcacttc cggcaccacc
    13441 tgaatgaagc gtgtgcccaa cgcgcgccac tgctggattt gctcgtcgct catcccccac
    13501 agtggattgc atccccagcc aattaccgcg aagttcgcgc cgatcgcgtt atcgagcagc
    13561 gtcacgtcgc cgttttccag cgtgactttc ggctgaataa acatcttgcc gaccggagag
    13621 tgcttcgctt cgccctcacg catcagcgca ccgccgtaat attgcggcat cggcttgaag
    13681 cgcatttcga ggaagtagcg ttttactggc ggcagataat tcaacagcca ggaaacgccg
    13741 tcacgtaacg taccctgcca gcgtttcggc ggagccagca cgttgcccgc cgtcacggac
    13801 aggtcaatca tcgctttggc gtgatcgcga cgttcttgtt gataggtatc gagcagcgca
    13861 tcgcgggctt tcccctggat aaccaacgcc agtttccatg cgaggttaaa ggcgtcgcgc
    13921 ataccactgt tatagccctg cccctgccat accggcatga tgtgcgcggc atcgcccgcc
    13981 agcagtacgc gatcaatacg gaaacgttgc gccagtcgcg cgttgtgggt gtagacacgc
    14041 tggcgaatca attcaacatt gtccggatta ggcagcactt tgcttaacag cttgcgcata
    14101 ttttgcggct cacgcagctg ctcttcggtt tctcccggca tcaccataaa ttcaaagcga
    14161 cgtaccgcat gaggcagcgc ggcagaaaca tacgggcgca ccggatcgca acacaaatag
    14221 atatgcggcg tacttaacgg atcgttggcg atatctacca caatccactg atttggcgca
    14281 gttttacctt caaacggcac attcagagtg cgacggacaa aacttgctcc accgtcacag
    14341 gctaccagcc actgggcttt gactatttcc cgctgccctt ctgccgtttt caggtgcaag
    14401 gtcacttcgt catcttgctg actgaaggcc tccagctcgc gggaaaacaa gcagcgcaca
    14461 ttcggaaaac gcgacacccc ttccagcatc accgcatcga cctgcggctg aataaaggcg
    14521 ttacggcgcg gccagccaaa ttcatcggtc attggctgaa tatcagcaaa acagcggcct
    14581 ttcggggtga gaaaacgcat cgcgtgccac ggcgtagtgt gcggcagaac atcatcgacc
    14641 aggccgaccg actgcatggt gcgcagcgcc tcgtcatcaa taccaatcgc acgcgggtag
    14701 tcgatcaact tatcgagttt ctccaccacc agcacgtcaa tgcccatctg gccgagatag
    14761 ttcgccatca tcagcccaac cgggccggca ccagcgatcg ccacctgaac gctatggtta
    14821 acagcaggct ggatgtcagg gtgttgtatt gccatttcag tacctcacga ctcggacaaa
    14881 atgtcgttgc gcgcacagta cagcgcaact tattttgtta aaaacatgta aatgattttt
    14941 tattgtgcgc tcagtatagg aagggtgttt tcggctacaa tcaaaacatg cccgaatgtg
    15001 caccaggtgc accacgttgt tttaactata gaaatgtcaa ttaatatgca gaacaatgag
    15061 cagacggaat acaaaaccgt gcgcggctta acccgcggtc taatgttatt aaatatgtta
    15121 aataaacttg atggcggtgc cagcgtcggg ctgctggcgg aactcagcgg cctgcatcgc
    15181 accactgtgc ggcgactgct ggagacgctg caggaagagg gatatgtccg ccgtagcccc
    15241 tccgatgata gttttcgact gaccatcaaa gtgcggcaat taagcgaagg atttcgtgac
    15301 gaacagtgga tttctgcact ggcggcccca ctgctgggcg atctgttgcg cgaagtggta
    15361 tggccgacag atgtgtccac gctggatgtt gatgcaatgg tggtacgcga aaccactcac
    15421 cgtttcagcc gcttatcctt tcaccgggca atggtcgggc gacgtttgcc gcttctgaaa
    15481 accgcctcgg gcctgacctg gctggccttt tgcccggaac aagaccgcaa ggaattaatc
    15541 gaaatgttag cctcccgccc cggtgatgac tatcaactgg cacgggaacc gttaaagctg
    15601 gaagccattc tggcgcgcgc gcgcaaagag ggttacggac agaactaccg cggctgggat
    15661 caggaggaga agatcgcctc tatcgccgta ccgctgcgca gtgaacaacg ggtgattggc
    15721 tgtctgaatc tggtgtatat ggcgagcgca atgaccattg aacaggcagc ggaaaagcat
    15781 cttccggcgc tacaacgggt agcaaaacag atcgaagaag gggttgaatc gcaggctatt
    15841 ctggtggccg gaaggcgaag cggcatgcat ttacgttgac accatcgaat ggcgcaaaac
    15901 ctttcgcggt atggcatgat agcgcccgga agagagtcaa ttcagggtgg tgaatgtgaa
    15961 accagtaacg ttatacgatg tcgcagagta tgccggtgtc tcttatcaga ccgtttcccg
    16021 cgtggtgaac caggccagcc acgtttctgc gaaaacgcgg gaaaaagtgg aagcggcgat
    16081 ggcggagctg aattacattc ccaaccgcgt ggcacaacaa ctggcgggca aacagtcgtt
    16141 gctgattggc gttgccacct ccagtctggc cctgcacgcg ccgtcgcaaa ttgtcgcggc
    16201 gattaaatct cgcgccgatc aactgggtgc cagcgtggtg gtgtcgatgg tagaacgaag
    16261 cggcgtcgaa gcctgtaaag cggcggtgca caatcttctc gcgcaacgcg tcagtgggct
    16321 gatcattaac tatccgctgg atgaccagga tgccattgct gtggaagctg cctgcactaa
    16381 tgttccggcg ttatttcttg atgtctctga ccagacaccc atcaacagta ttattttctc
    16441 ccatgaagac ggtacgcgac tgggcgtgga gcatctggtc gcattgggtc accagcaaat
    16501 cgcgctgtta gcgggcccat taagttctgt ctcggcgcgt ctgcgtctgg ctggctggca
    16561 taaatatctc actcgcaatc aaattcagcc gatagcggaa cgggaaggcg actggagtgc
    16621 catgtccggt tttcaacaaa ccatgcaaat gctgaatgag ggcatcgttc ccactgcgat
    16681 gctggttgcc aacgatcaga tggcgctggg cgcaatgcgc gccattaccg agtccgggct
    16741 gcgcgttggt gcggatatct cggtagtggg atacgacgat accgaagaca gctcatgtta
    16801 tatcccgccg ttaaccacca tcaaacagga ttttcgcctg ctggggcaaa ccagcgtgga
    16861 ccgcttgctg caactctctc agggccaggc ggtgaagggc aatcagctgt tgcccgtctc
    16921 actggtgaaa agaaaaacca ccctggcgcc caatacgcaa accgcctctc cccgcgcgtt
    16981 ggccgattca ttaatgcagc tggcacgaca ggtttcccga ctggaaagcg ggcagtgagc
    17041 gcaacgcaat taatgtgagt tagctcactc attaggcacc ccaggcttta cactttatgc
    17101 ttccggctcg tatgttgtgt gaaattgtga gcggataaca atttcacaca ggaaacagct
    17161 atgaccatga ttacggattc actggccgtc gttttacaac gtcgtgactg ggaaaaccct
    17221 ggcgttaccc aacttaatcg ccttgcagca catccccctt tcgccagctg gcgtaatagc
    17281 gaagaggccc gcaccgatcg cccttcccaa cagttgcgca gcctgaatgg cgaatggcgc
    17341 tttgcctggt ttccggcacc agaagcggtg ccggaaagct ggctggagtg cgatcttcct
    17401 gaggccgata ctgtcgtcgt cccctcaaac tggcagatgc acggttacga tgcgcccatc
    17461 tacaccaacg tgacctatcc cattacggtc aatccgccgt ttgttcccac ggagaatccg
    17521 acgggttgtt actcgctcac atttaatgtt gatgaaagct ggctacagga aggccagacg
    17581 cgaattattt ttgatggcgt taactcggcg tttcatctgt ggtgcaacgg gcgctgggtc
    17641 ggttacggcc aggacagtcg tttgccgtct gaatttgacc tgagcgcatt tttacgcgcc
    17701 ggagaaaacc gcctcgcggt gatggtgctg cgctggagtg acggcagtta tctggaagat
    17761 caggatatgt ggcggatgag cggcattttc cgtgacgtct cgttgctgca taaaccgact
    17821 acacaaatca gcgatttcca tgttgccact cgctttaatg atgatttcag ccgcgctgta
    17881 ctggaggctg aagttcagat gtgcggcgag ttgcgtgact acctacgggt aacagtttct
    17941 ttatggcagg gtgaaacgca ggtcgccagc ggcaccgcgc ctttcggcgg tgaaattatc
    18001 gatgagcgtg gtggttatgc cgatcgcgtc acactacgtc tgaacgtcga aaacccgaaa
    18061 ctgtggagcg ccgaaatccc gaatctctat cgtgcggtgg ttgaactgca caccgccgac
    18121 ggcacgctga ttgaagcaga agcctgcgat gtcggtttcc gcgaggtgcg gattgaaaat
    18181 ggtctgctgc tgctgaacgg caagccgttg ctgattcgag gcgttaaccg tcacgagcat
    18241 catcctctgc atggtcaggt catggatgag cagacgatgg tgcaggatat cctgctgatg
    18301 aagcagaaca actttaacgc cgtgcgctgt tcgcattatc cgaaccatcc gctgtggtac
    18361 acgctgtgcg accgctacgg cctgtatgtg gtggatgaag ccaatattga aacccacggc
    18421 atggtgccaa tgaatcgtct gaccgatgat ccgcgctggc taccggcgat gagcgaacgc
    18481 gtaacgcgaa tggtgcagcg cgatcgtaat cacccgagtg tgatcatctg gtcgctgggg
    18541 aatgaatcag gccacggcgc taatcacgac gcgctgtatc gctggatcaa atctgtcgat
    18601 ccttcccgcc cggtgcagta tgaaggcggc ggagccgaca ccacggccac cgatattatt
    18661 tgcccgatgt acgcgcgcgt ggatgaagac cagcccttcc cggctgtgcc gaaatggtcc
    18721 atcaaaaaat ggctttcgct acctggagag acgcgcccgc tgatcctttg cgaatacgcc
    18781 cacgcgatgg gtaacagtct tggcggtttc gctaaatact ggcaggcgtt tcgtcagtat
    18841 ccccgtttac agggcggctt cgtctgggac tgggtggatc agtcgctgat taaatatgat
    18901 gaaaacggca acccgtggtc ggcttacggc ggtgattttg gcgatacgcc gaacgatcgc
    18961 cagttctgta tgaacggtct ggtctttgcc gaccgcacgc cgcatccagc gctgacggaa
    19021 gcaaaacacc agcagcagtt tttccagttc cgtttatccg ggcaaaccat cgaagtgacc
    19081 agcgaatacc tgttccgtca tagcgataac gagctcctgc actggatggt ggcgctggat
    19141 ggtaagccgc tggcaagcgg tgaagtgcct ctggatgtcg ctccacaagg taaacagttg
    19201 attgaactgc ctgaactacc gcagccggag agcgccgggc aactctggct cacagtacgc
    19261 gtagtgcaac cgaacgcgac cgcatggtca gaagccgggc acatcagcgc ctggcagcag
    19321 tggcgtctgg cggaaaacct cagtgtgacg ctccccgccg cgtcccacgc catcccgcat
    19381 ctgaccacca gcgaaatgga tttttgcatc gagctgggta ataagcgttg gcaatttaac
    19441 cgccagtcag gctttctttc acagatgtgg attggcgata aaaaacaact gctgacgccg
    19501 ctgcgcgatc agttcacccg tgcaccgctg gataacgaca ttggcgtaag tgaagcgacc
    19561 cgcattgacc ctaacgcctg ggtcgaacgc tggaaggcgg cgggccatta ccaggccgaa
    19621 gcagcgttgt tgcagtgcac ggcagataca cttgctgatg cggtgctgat tacgaccgct
    19681 cacgcgtggc agcatcaggg gaaaacctta tttatcagcc ggaaaaccta ccggattgat
    19741 ggtagtggtc aaatggcgat taccgttgat gttgaagtgg cgagcgatac accgcatccg
    19801 gcgcggattg gcctgaactg ccagctggcg caggtagcag agcgggtaaa ctggctcgga
    19861 ttagggccgc aagaaaacta tcccgaccgc cttactgccg cctgttttga ccgctgggat
    19921 ctgccattgt cagacatgta taccccgtac gtcttcccga gcgaaaacgg tctgcgctgc
    19981 gggacgcgcg aattgaatta tggcccacac cagtggcgcg gcgacttcca gttcaacatc
    20041 agccgctaca gtcaacagca actgatggaa accagccatc gccatctgct gcacgcggaa
    20101 gaaggcacat ggctgaatat cgacggtttc catatgggga ttggtggcga cgactcctgg
    20161 agcccgtcag tatcggcgga attccagctg agcgccggtc gctaccatta ccagttggtc
    20221 tggtgtcaaa aataataata accgggcagg ccatgtctgc ccgtatttcg cgtaaggaaa
    20281 tccattatgt actatttaaa aaacacaaac ttttggatgt tcggtttatt ctttttcttt
    20341 tactttttta tcatgggagc ctacttcccg tttttcccga tttggctaca tgacatcaac
    20401 catatcagca aaagtgatac gggtattatt tttgccgcta tttctctgtt ctcgctatta
    20461 ttccaaccgc tgtttggtct gctttctgac aaactcgggc tgcgcaaata cctgctgtgg
    20521 attattaccg gcatgttagt gatgtttgcg ccgttcttta tttttatctt cgggccactg
    20581 ttacaataca acattttagt aggatcgatt gttggtggta tttatctagg cttttgtttt
    20641 aacgccggtg cgccagcagt agaggcattt attgagaaag tcagccgtcg cagtaatttc
    20701 gaatttggtc gcgcgcggat gtttggctgt gttggctggg cgctgtgtgc ctcgattgtc
    20761 ggcatcatgt tcaccatcaa taatcagttt gttttctggc tgggctctgg ctgtgcactc
    20821 atcctcgccg ttttactctt tttcgccaaa acggatgcgc cctcttctgc cacggttgcc
    20881 aatgcggtag gtgccaacca ttcggcattt agccttaagc tggcactgga actgttcaga
    20941 cagccaaaac tgtggttttt gtcactgtat gttattggcg tttcctgcac ctacgatgtt
    21001 tttgaccaac agtttgctaa tttctttact tcgttctttg ctaccggtga acagggtacg
    21061 cgggtatttg gctacgtaac gacaatgggc gaattactta acgcctcgat tatgttcttt
    21121 gcgccactga tcattaatcg catcggtggg aaaaacgccc tgctgctggc tggcactatt
    21181 atgtctgtac gtattattgg ctcatcgttc gccacctcag cgctggaagt ggttattctg
    21241 aaaacgctgc atatgtttga agtaccgttc ctgctggtgg gctgctttaa atatattacc
    21301 agccagtttg aagtgcgttt ttcagcgacg atttatctgg tctgtttctg cttctttaag
    21361 caactggcga tgatttttat gtctgtactg gcgggcaata tgtatgaaag catcggtttc
    21421 cagggcgctt atctggtgct gtgtctggtg gcgctgggct tcaccttaat ttccgtgttc
    21481 acgcttagcg gccccggccc gctttccctg ctgcgtcgtc aggtgaatga agtcgcttaa
    21541 gcaatcaatg tcggatgcgg cgcgagcgcc ttatccgacc aacatatcat aacggagtga
    21601 tcgcattgaa catgccaatg accgaaagaa taagagcagg caagctattt accgatatgt
    21661 gcgaaggctt accggaaaaa agacttcgtg ggaaaacgtt aatgtatgag tttaatcact
    21721 cgcatccatc agaagttgaa aaaagagaaa gcctgattaa agaaatgttt gccacggtag
    21781 gggaaaacgc ctgggtagaa ccgcctgtct atttctctta cggttccaac atccatatag
    21841 gccgcaattt ttatgcaaat ttcaatttaa ccattgtcga tgactacacg gtaacaatcg
    21901 gtgataacgt actgattgca cccaacgtta ctctttccgt tacgggacac cctgtacacc
    21961 atgaattgag aaaaaacggc gagatgtact cttttccgat aacgattggc aataacgtct
    22021 ggatcggaag tcatgtggtt attaatccag gcgtcaccat cggggataat tctgttattg
    22081 gcgcgggtag tatcgtcaca aaagacattc caccaaacgt cgtggcggct ggcgttcctt
    22141 gtcgggttat tcgcgaaata aacgaccggg ataagcacta ttatttcaaa gattataaag
    22201 ttgaatcgtc agtttaaatt ataaaaattg cctgatacgc tgcgcttatc aggcctacaa
    22261 gttcagcgat ctacattagc cgcatccggc atgaacaaag cgcaggaaca agcgtcgcat
    22321 catgcctctt tgacccacag ctgcggaaaa cgtactggtg caaaacgcag ggttatgatc
    22381 atcagcccaa cgacgcacag cgcatgaaat gcccagtcca tcaggtaatt gccgctgata
    22441 ctacgcagca cgccagaaaa ccacggggca agcccggcga tgataaaacc gattccctgc
    22501 ataaacgcca ccagcttgcc agcaatagcc ggttgcacag agtgatcgag cgccagcagc
    22561 aaacagagcg gaaacgcgcc gcccagacct aacccacaca ccatcgccca caataccggc
    22621 aattgcatcg gcagccagat aaagccgcag aaccccacca gttgtaacac cagcgccagc
    22681 attaacagtt tgcgccgatc ctgatggcga gccatagcag gcatcagcaa agctcctgcg
    22741 gcttgcccaa gcgtcatcaa tgccagtaag gaaccgctgt actgcgcgct ggcaccaatc
    22801 tcaatataga aagcgggtaa ccaggcaatc aggctggcgt aaccgccgtt aatcagaccg
    22861 aagtaaacac ccagcgtcca cgcgcgggga gtgaatacca cgcgaaccgg agtggttgtt
    22921 gtcttgtggg aagaggcgac ctcgcgggcg ctttgccacc accaggcaaa gagcgcaaca
    22981 acggcaggca gcgcccacca ggcgagtgtt tgataccaag tttcgctatg ttgaactaac
    23041 cagggcgtta tggcggcacc aagcccaccg ccgcccatca gagccgcgga ccacagcccc
    23101 atcaccagtg gcgtgcgctg ctgaaaccgc cgtttaatca ccgaaggcat caccgcctga
    23161 atgatgccga tccccacccc accaagcagt gcgctgctaa gcagcagcgc actttgcggg
    23221 taaagctcac gcatcaatgc accgacggca atcagcaaca gactgatggc gacactgcga
    23281 cgttcgctga catgctgatg aagccagctt ccggccagcg ccagcccgcc catggtaacc
    23341 accggcagag cggtcaacag ggcagccacg ctaaagctca ttccgctcgc ctggcgcaat
    23401 tgcggtagca gtggcccgac ggaggtgagc agtggtcgca tattaagacc aatcagcacc
    23461 agtaccagca gcatcgtgaa cgtcttttga tggttgcgca tggctgtcag aacggtttgg
    23521 tcggcagata tttaccatct aaggtgatga ccgcacgttc gccaccttcc gggtccgcca
    23581 ctttcttaac gtcgagtttg aagttaatcg cgctaataat gccatcgcca aatttctcat
    23641 gaaccaacgc tttcagggtt gtaccgtaca cctgcaacat ttcatagaaa cgatacatcg
    23701 ttgggtcagt tggaatacgg tcatcaatgc agccacgcag tggaatcatc tgcaacagta
    23761 gaatggagtc ttcgtcgaga tccagcttcg ccccgaccag gcgggcggcg tcggcaggaa
    23821 gcgcctgctg acccagcaaa gccgcggtta caaaggcttc tgccagaccg gtgccgtcgg
    23881 caatctcggc aaatgagaga tcttttttag ctttgctgag caaaatggca tcggcaagat
    23941 caagacgaat attgcggtta atttgtgact gaatcatggt ggaactcctg atggtttaaa
    24001 aataaggtta cgctgcggtc ggttggcgta gcggtatggc acaaacgcga ggattagcgg
    24061 ccagtggcac aaactggcgg gttgcgccgt caaaagctgc gatgctgccg ctttcaatgt
    24121 cgtagaccca gccgtgcagg gcgatccgcc cctcttcgag cgccaggcgc accgatggat
    24181 gagtttgcaa attagccaac tgagcaatga cgttttcacg taccatcgcc gcagcttttg
    24241 acggtaaatc ggaatgcggg cgcgcctcat taacgacgcg ggctgaatcg gcataacgca
    24301 gccagtggga gacggcaggc atatggtcca tgcactgaca gctggcaatg gcggtcatcg
    24361 cgccacagtt ggaatgacca caaatcacaa tgtcagatac ccgaagcgca gcgacggcat
    24421 actccaccga agcagaaacg ccaccgggtt ccggcccgta ggaagggacg atattgcccg
    24481 cgttgcgaat aacgaacaga tcgccaggct cacgttgcgt caccagctca gggaccagac
    24541 ggctgtcgga gcaggagata aaaagtgtgc gcgggctttg ctgtgtcgcc agctgtttaa
    24601 acaaggcttc ccgcttcgga aatgcctcgc gctggaattt aaggaatcca tcaataatct
    24661 ctttcaccgt taacctctgt ctgtctctgg aatgagaggc agactactcg ccgattgtca
    24721 taaggtaaaa gtctcattta tgatgagttc cattggattt acttataggt tgcgaatgct
    24781 ctctcgacat atcaattatt ttcttgccgt ggctgaacat ggcagcttca cccgtgccgc
    24841 cagtgcgttg cacgtctccc aacctgcgct ttcccagcag attcgccagt tagaggagag
    24901 tttaggcgtg ccgctgtttg accgtagcgg gcgaacgatt cgtctcactg atgcaggaga
    24961 agtctggcga cagtacgcca gccgggcgtt acaggaactg ggggcgggta aacgggcgat
    25021 tcatgatgtt gccgatctga cgcgaggatc gctgcgtatc gccgtcaccc ccacctttac
    25081 gagctacttt atcggcccct taatggcgga tttctatgcg cgctatccca gcatcacgct
    25141 ccagctacag gaaatgtcgc aggagaaaat cgaggatatg ctttgccgcg acgagttgga
    25201 cgttgggatt gccttcgcgc ctgtgcattc gccggagctg gaggcaattc ctttactgac
    25261 agaaagttta gcgttagtcg tggcgcaaca tcatccgctg gccgtccatg aacaggtggc
    25321 gttgagtcgc ttgcatgatg aaaaactggt cctgctcagc gcggaatttg ccaccagaga
    25381 gcaaattgac cactactgcg agaaagcggg gctacatcca caggtggtca ttgaggcgaa
    25441 ctcaattagc gcggttctgg agctgattcg ccgcacttcc ctttccacat tgttaccagc
    25501 agcgattgcc acacaacatg acgggcttaa agctatttct cttgccccgc cactactgga
    25561 gagaacggcg gttttgttgc ggcggaaaaa tagctggcag acagccgccg cgaaggcatt
    25621 tttgcacatg gcgttggata aatgcgcggt tgttggcgga aatgaatcac ggtagccgct
    25681 gacacaggtc tgcggctgga attgcctgat gcgctacgct tatcaggcct acgagttcag
    25741 tgctctacgt aggccggata aggcgttcac gccgcatccg gcataaacta cagctggcag
    25801 acagccgctg cgaaggcatt tttgcacatg gcgttggagg aatgcgcggt tgttggcggg
    25861 aatgaatcac ggtagccgct gacacagatc agcggctgga attgcctgat gcgctacgct
    25921 tatcaggcct acgagttcag tgctctacgt aggccggata aggcgttcac gccgcatccg
    25981 gcataaacta agctcgctgt aacccagtcg ttcaacgttt gtaatcgatg gcttctggct
    26041 gctccagata tacggtggtt tgtgccggtt gtgtgctggc aatcaccttg ccgccacgta
    26101 ccgaataacg taccggaacc tgacggcgca gcgcatcaaa cccattttca gccggcagga
    26161 taatcaggtt ggcgctgttt ccggcggcaa tgccgtaatc ctgcaaattc aacgtccttg
    26221 cgctgtggtg ggtgattaaa ttcaggccat cgttaatctg cccgtagccc atcaactggc
    26281 aaacatgcag ccccatatgc agcacttgca gcatattcgc cgttcccagc ggataccacg
    26341 gatcgaagac atcatcgtga ccaaagcaga cgttaatgcc ggactccagc atctctttaa
    26401 cgcgcgtgat gccgcgacgt tttggatacg tatcgaaacg tccttgcaga tgaatattga
    26461 ccagcgggtt ggcgacaaag ttaataccgg acattttcag caagcggaac aggcgtgagg
    26521 tatacgcccc gttataggag tgcattgccg tggtgtggct ggcggtgact cgcgcgccca
    26581 tgccttcatg gtgcgccagg gcagcaacgg tttcgacaaa gcgcgactgc tcgtcatcga
    26641 tctcatcaca gtgaacgtcg atgagacggt cgtatttttg cgccagggcg aaggttttat
    26701 gcagcgactc cacgccgtat tcacgggtaa attcaaaatg cggaatcgcc cccactacat
    26761 ctgcccctaa gcgtaacgcc tcttccagca acgcttcacc gttgggatac gacaaaatcc
    26821 cttcctgagg gaaggcgacg atttgcagat caatccacgg cgcgacttcc tgcttcactt
    26881 ccagcattgc tttcagcgca gttagcgttg catccgaaac atcgacatgg gtacgcacat
    26941 gctgaatgcc gttggcaatc tgccatttca gcgtttgcca tgcgcgttgt ttcacatcgt
    27001 catgggttaa taacgctttg cgctcggccc agcgttcaat gccttcaaac agcgtgccgg
    27061 actgattcca gttcggttgt ccggcggttt gcgtggtgtc caggtgaata tgtggctcca
    27121 caaacggcgg tataactaaa ccttgttcgg catccaggct gttttcagtt atgggcatca
    27181 cgccggattg cgcatcaatg gcgctgattt ttccgtcctg cagatgaatc tgccacagcc
    27241 cctcttcgcc tggtaaccgg gcgttaataa ttgtttgtaa agcgttattc gacactgtta
    27301 gcctccacat gcgtcattgc tgctgtcgtt ttacgattca aaatcgggtt aaggatcaga
    27361 tagctcagcg cgccacctaa taccgcgttg accggaacaa ttcccggtaa ccagtggcct
    27421 gcagcaatcc ccaaggcgac cgccagaatc gccacccaat tgacactcat catacgcgtg
    27481 gtcgcaaagt gctcatagcg gcgacggttc atcagatagt cggcgatgat cacgccaccc
    27541 actggaggaa tagctgccga aaggaaggtc aaccagccga caaaattgtt atacagccat
    27601 aatgcgcaga ccgtaccgat aataccgttg attaccgaaa gggttttgct cgacatcccg
    27661 gtaatgttgg cgaaacctaa acccgacgca tagagtgcgt tatcgttggt ggtccagata
    27721 ttcagcccca gcaccacaat cgcaggcagc agcaggccct gagcaatcat cacatcagag
    27781 atatccgcca tgcccagtgc cgcagcgccc gctgcaccga aaataaacat caacgagttg
    27841 ccgaggaaaa aggccaccat cgccaccagc accgccagtt tggcattgcg accaaaccgg
    27901 acaaagtcag cggtgagcgt acccgcactg ataaatgacc ccacaaccag cgccagcgcg
    27961 acattgaaat ctaacggttg tgcgggaacg accgctttta atgcgtccag gccgcccatg
    28021 ccgttaacag ccagccacac ggaataaccg cccaggcagg cgatagccgg aaccgcaatc
    28081 accgaaagaa ccgtcagcgc cgaaatgcca aaaaagacgg tgacggtcat cagtaaaccg
    28141 gaaacggcaa tcagcaaatt aatatccagc ccggttgcct tacccaccgg aatggcaaac
    28201 atcgccacac cgacgccaaa ccagccaacc tgagttccgc ccagtagcag tgaaggcagc
    28261 catgagcctt taacaccaaa cgagaagcga gcaagaagat gagtggtcag gccggttttt
    28321 gcgccaatgt aaccgagaaa tgaagtgtaa ataccgagga gaagattacc gatgagaact
    28381 gcgaggaaga aatcatgata gctaagaccg gttccgagag tgccgccggt ccacatactg
    28441 gcggaaaaga aggttaatcc cagcatgacg aacgtcaatg ccaatacccc tttccgcgcc
    28501 gactgcggga ctggcccctg gctaaagttg ttatcttgcg acacgaaatt cccccttttt
    28561 gctgtttgaa acccaaaaaa tccgccgcat tctattcatc tgaagataaa aagcaatcgt
    28621 tttcgtgggg aaatatattt tttatatgaa tgagtgcaaa aaggtggggg aaaaattatc
    28681 ggtgtaaaaa cagtgggtag gcctgataag acgcgtcagc gtcgcatcag gcatctgagc
    28741 atggtgtcgg atgcgacgcg agcgccttat ccgacctacg gttcaggtcc gtaggcatga
    28801 taaaacgcgt cagcgtcgca tcaggcatcg gcacacagtg ccggatgcac cgcgcgacgc
    28861 atccgacaat aacctactct tccatcgcct ggcggatctg atccaacgac gcaggatcat
    28921 caatggtcgt cagatctcca ggatcgcgtc cttcgcaaat cgcctggatc gtgcggcgca
    28981 gcatttttcc ggatcgcgtt tttggcaatt gcgagacaaa ccagacgtgc gccgggcggc
    29041 caaagttgcc aatctggctg tccaccagcg ccataatcgc cttctcttgc gagtgcgcca
    29101 catcacgatc ttccagactg tcgctctctt tcggaatgac aaacgccacc gccacctgcc
    29161 ctttcagcgc atctttcacc ccaaccaccg ccacttcggc aacgcccgga tggctggaga
    29221 tactctcttc aatctcgcgc gtccccagcc gatgcccggc aacgttaatt acatcgtcag
    29281 tgcgcccgag aataaagtga taaccgtcag cgtcacggat gccccagtca aaggtggcgt
    29341 acaccgggcg ggaaaacagc gaccagtaag tcttcacaaa gcggccgtcg tcgccccaga
    29401 tggtctgaat acaccccggc ggcagcggcc cttccaccac cagcatccct ttctcgttga
    29461 cgccacacgg ttcgccggtg acttcattaa gcaactgcac gttatagcca tacatcggca
    29521 caccggggct tcccagacgc gtcggcctgt cgtccagacc gcgagcaatc gccataatcg
    29581 gccagccgga ttcggtctgc cagtagttgt cgatgaccgg cacatccagc gtattgctca
    29641 cccaactggc ggtcggctcg tccagcggtt ctccagccag atagagcact tccagcgacg
    29701 agagatcgtg tttgcgaatt tcagcggtag ggaatttttt cagcacgcga atggcggtcg
    29761 gcgctgagaa catccggcta acctgatatt tctcgacgat tttccaccac acgccgcagt
    29821 ccggccaggt cggcaatcct tcgtaaacga tagtcgccat ccccgccagc agcggcgcgt
    29881 aaacgatata cgaatgcccc accacccagc cgatatccga tgcgcaaaag aacacgctgc
    29941 ccgctttgcc gccaaaaatg gtgtccatcg aggtcgccag cgccaccgca tatccgccga
    30001 cgtcacgctg cacgccttta ggtttgccgg tcgtgccgga agtgtagaga atgcaggagg
    30061 tttcgttgga ttccagccac gccaccggta cccgcgcgcc gatgtgttga tggcgcaacg
    30121 acgcgaaatc gacatcccgc ccgctgacgc gcgccatttt cgccagcccg cgatccacca
    30181 gcaaaacatg gcgtggctgg tgctgcgcct gacttatcgc atcgtcgagc aattttttat
    30241 agggaatgat tttgccaccg cgcgctccgg catcagccga gacaatcagc accggtttag
    30301 cgtcatcaat tcgcgccgcc acgctgtgcg aggcaaatcc accaaacacc accgagtgaa
    30361 tagcgccaat gcgcgcgcag gccagcagag taatatgcgc ttcggcaatc atcggcatat
    30421 acaccagcac ccgatcgccg cgctgcacac ccaatgaacg caacattgag gccaccgcgt
    30481 tcacttcgtc atgcagctga cgaaaggtaa aggtgcgctc ttcttctgtt tccgaagaga
    30541 cggcaatcag cgccagcgcc tctggctgtt tctccagcca gcggtcgatg gcgttgtggc
    30601 acaagttggt tcggccttca caaaaccaac gggcaaacgg cggattgctg tgatcgagcg
    30661 tttgcgtaaa gggcgtctgc cagtcaatac gccgggcctg ctcggcccag aactgctccg
    30721 gttcgttaat cgaacgctga taaaattcgc taaaagacat aatgctctcc tgttgaactt
    30781 acgccttacc gccgtttact taaatgacgt acaggtcgag atactcattg accggcatct
    30841 gttccaggcg agctctgtcg agagaaacct ccagaatgcg ctgctgttgg cgagtcggga
    30901 actggcgcgc gagattgatt ttgaatttat cgaccagttt cggaatacca tcctgacggc
    30961 ggcgagcatg accaatgggg tactccacca ccacttcttc aaatcgtgtg ccgtcggtga
    31021 actcaagggt aatggcattg gcgatggcgc gtttttccgg gtcgtggtag tcagcggtaa
    31081 atgccggatc ttcaaagcaa ttgatcttct cgcgcagggc gtcaatgcgt ttatcttgcg
    31141 caacgttgtc ctcgtaatct gccgccgtta agcgcccgaa tagcagcggg atcgccacca
    31201 tgtactgaat gcagtgatcg cggtctgccg ggttattgag cggccctttt ttgtcgatga
    31261 tgcgaataca ggcttcgtgg gtgcgaatgg tcactttttc gatatccgcc gccgttttgc
    31321 ctgctgcctg catctgttca tagagcgtca tcgctgcttc aactgccgtc tgggagtgga
    31381 actccgccgg gaaggagatt ttgaacagca cattttccat aacgtaggaa ccgtacgggc
    31441 gctggaagcg gaacgattca cctttaaagg agacgtcgta gaagccccac accggcgcag
    31501 tcagggctga cgggtaaccc atttcgcccg ttttcgccat cagtgccaga cgtaccgcgc
    31561 gggaagtggc atcgcccgcc gcccaggatt tacgcgtgcc ggtgttcggc gcatggcgat
    31621 aggtgcgcag cgactgaccg tccacccacg ccagcgaaac ggcgttgaga atttcctcgc
    31681 gggtcaggcc gagcatttcg gcgaccacgg cggtggaagc cactttcact aacagaacgt
    31741 ggtcgaggcc gacgcggtta aaggagtttt ccagcgcgat gcagccctga atttcatggg
    31801 ctttgatcat tgcggtcagc acctgtttca tggtcaacgg cactttgccg ctggcgaccg
    31861 cgttgcgcga aagccagtcc gccgttgcca gaatgccgcc gaggttgtcg gaaggatggc
    31921 cccactccgc cgccagccag gtatcgttga aatcgagcca gcggatcatc gcgccgatgt
    31981 taaatgccgc ctggacgggg tcgagctgga actgagttcc ggggacgcgc acgccgttgg
    32041 gtacgacggt gccgggaaca attggcccca gcagtttttt acaggccggg tattcgagag
    32101 cttccagacc gcagccgagc gtgtcgagca ggcagtaatg tgcggtgtcg taggccactt
    32161 tagagctgat ttcgtagttc atgacgtaat cgacgatatc aacgatttca cgatcaaatt
    32221 ccgggcggat gttgttgatt tgagctgaca ttgggtacgt ttccttattg ttattcgtag
    32281 aggtttactg gcgcttatcc agcgcgacaa acgggcggtc ttccggtcca acataattgg
    32341 cggaaggacg gataattttg ttgtcctgac gttgttcgat aatgtgcgcc gcccagccgg
    32401 tgacgcgggc gataacaaac agtggtgtga acatctcggt gggaacgccc atcatgttgt
    32461 aggaaacagc agagaaccag tcgagattgg ggaacatctt tttgctctcc cacatcaccg
    32521 tttccaggcg atcggcgatg ttgtacatct tcagcgagcc gccttcctgc gagagctgct
    32581 tcgccacacg tttaatcacc tggtggcgcg ggtcagcgat ggtgtaaacc ggatgaccaa
    32641 aaccaatgac cacttctttg ttttccacgc gcttgcggat atctgcttcg gcttcgtccg
    32701 gcgtttcgta gcgttgctgg atctccagcg acacttcatt cgccccgccg tgttttggcc
    32761 cgcgcagtgc gccaatcgcg ccaataatcg cggaatacat atcagagccg gtgcccgcaa
    32821 tcacccgact ggtaaaggtg gaggcgttaa actcgtgttc ggcgtacagc accagcgaga
    32881 tatgcatcgc cttttcccag ctttgcgatg gcttttcgcc gtgcagcaga tgcaggaagt
    32941 gaccgccgat ggagtcgtca tcggtttccg gttggatgcg ttcgccgttg tggctgtagt
    33001 gataccaata aaggagaatc gagctaagcg acgccagcag tttgtcggca atatcccgcg
    33061 cgccagagac ggtatgcccc tctttttctg gcagcgtgca gccgagcgcg gaaacaccgg
    33121 tgcgcataac atccatcggg tgcgacgccg ccggtaaggc ttccagcacg gtacgcacgt
    33181 tagccggtaa accgcgcagg gctttcagtt tcgttttgta agcggcgagt tcgtcacggg
    33241 tcggcagttt gccgtggatc agcagatgcg ccacttcttc aaattcgcaa tgtttcgcca
    33301 gatcaagaat atcgtagccg cggtaatgca ggtcattgcc acttttaccc acggtgcaga
    33361 gcgccgtatt gcccgccgga acgccagaaa gtgccacaga ttttttcggt ttaatgacat
    33421 gggtactgtt ttgcaggatc gttgtgtcgc tcatgttgtc ctcgtcattg ttatcatttg
    33481 tagggtcgag attgttgtcg gatgcgacgc tatgcgtctt atccgaccta cagttcagtt
    33541 caccccgtag gcctgataag tcgcgtcagc ggcgcatcag gcatcggttg tcggatgcga
    33601 cgctatgcgt cttatccgac ctacagttca gtgcaccccg taggcctgat aagtcgcgtc
    33661 agcggcgcat caggcatcgg ttgtcggatg cgacgccatc cgtcttatcc gacctacagt
    33721 tcagtgcacc tcgtaggcct gataagtcgc gtcagcgacg catcaggcat cggctgtcga
    33781 atacaatcaa cgggcgtttt ttatttcacc tggctacggg caaacaggtt gtcgagcttc
    33841 tcttcgtact ggtagtagtt gatgctttcg tacagctcgt tgcgggtctg catggtgtcg
    33901 atgacgcttt tctgcgtgcc ttcctggcgc aggacgttgt agacatgttc agcggcgcgg
    33961 ttcatggcgc ggaacgctga aagtgggtac agcgccattg cgacatgggc gctgcgtaat
    34021 tcgtcggtgg taaacagcgg cgtggcacca aattcggtga tgttggcgag gatcggcacc
    34081 tgcaccgcat cggcaaactg gcggtacatg gcgagttcgg taatcgcctc cgggaacaac
    34141 atctcggcac ccgcttcaac ataggcctgc gcacgctcga tcgccgcatc cagcccctct
    34201 accgccagag catcggtgcg cgccatgatc acaaaatcag gatcggtttt cgcatccacc
    34261 gccgcgcgga tccgatccac catctcttct ttcgagacga tcgctttatt cggacgatga
    34321 ccgcagcgtt tcgcaccaac ctgatcttca atatgcaatc ctgccgcacc ggctttaatc
    34381 atcgatttca cggtgcgcgc cacgttaaag gccgaagaac caaaaccgat atccgcatcc
    34441 accagcagcg gcagcgaaca aacgtcggtg atacggcgaa tgtcggtcag cacatcatca
    34501 agggtagaaa taccgagatc gggcagcccc agcgaacctg ccgccacgcc accgccagaa
    34561 agataaattg cctgatatcc ggcacgctgc gccaacagcg catgattagc gttgatggtg
    34621 ccaacaatct gcaatggatt ttctttagtc agtgcagcgc gaaacgcttt acctggagag
    34681 tgtagagaca tagcccatcc tttgttatca acttgttatt tgcgttgata aagacaaagc
    34741 aaggggtgtg ccacaattgc cttaataaaa ttaaatgttt aatttcaatt tgttagagat
    34801 aaagtcatga actaatccgc aaatatgcgt ttcagttaac gtttcaggca atgtttcacc
    34861 gcgtttcatt gcaacaatta tgaaacaaga ctaaacccaa tattcggttt cttaactttg
    34921 cggtgcgcta tggcacatcc accacggctt aatgacgaca aaccggttat ctggacggta
    34981 tctgtaacgc gcctgttcga gctgtttcgc gatatcagcc tcgagtttga tcacctggcg
    35041 aacattaccc ctattcagct tggctttgaa aaagcagtga cctacatccg caagaaactg
    35101 gcaaacgaac gctgtgacgc catcatcgcg gctggctcta acggcgcgta cctgaaaagc
    35161 cgcctgtcag tgccagttat tttgattaaa ccgagcggct acgatgtgtt acaggcactg
    35221 gcaaaagccg gaaaactcac ctcttctatc ggcgttgtca cctatcagga aaccattcca
    35281 gcgctggtgg cgtttcaaaa aacctttaat ttgcgcctcg accaacgtag ctacattacc
    35341 gaggaagacg cacgcgggca gattaacgag ctaaaagcta acggcaccga agcggtggtc
    35401 ggcgcagggc tgattaccga tttggcagaa gaagccggaa tgaccggaat ttttatctat
    35461 tccgccgcca ccgtgcgcca ggcgttcagc gatgcgctgg atatgacgcg catgtcgtta
    35521 cgccataaca ctcacgatgc cacccgcaac gccctgcgta ctcgttacgt gctgggcgat
    35581 atgctcggtc aatcaccaca gatggaacaa gtacggcaga ctattttgct gtatgcccgc
    35641 tccagtgcgg cggtgttgat tgagggggaa acggggacgg gcaaagagct ggcggcccag
    35701 gcgattcatc gggaatattt tgcccgccac gatgcgcgac agggcaaaaa gtcgcatccg
    35761 tttgttgccg tcaactgcgg ggcgattgcc gaatcgctgc tggaagcaga actgtttggc
    35821 tatgaggaag gggcgtttac cggctcgcga cgcggaggtc gcgccgggct gttcgaaatt
    35881 gcccacggcg gtacgctgtt tctggatgag attggcgaaa tgccgctacc tttgcagacc
    35941 cggctgctgc gggtgctgga agaaaaagag gtcacccgcg tcggcgggca tcagcctgtt
    36001 ccggtagatg tacgggtcat tagcgccact cactgcaatc tggaagaaga tatgcagcaa
    36061 ggacgttttc gccgtgatct gttttatcgg ctgagtattt tgcgtctgca attgccacca
    36121 ctgcgcgagc gggtggcgga tattcttccg ctggcggaaa gctttttgaa agtgtctctg
    36181 gcggcgctct ccgccccatt ttctgctgca ttacgccagg ggttacaggc aagtgaaact
    36241 gtgctgctgc actacgactg gccaggcaat attcgtgaac tgcgcaatat gatggaacga
    36301 ctggcgctgt ttttaagtgt ggaaccgacg ccggatttaa cgccgcagtt tatgcaactg
    36361 ctactgccgg aactggcgcg cgagtcggcg aaaactcccg ctccacgctt actgacacca
    36421 caacaggcac tggagaaatt taatggcgat aaaacagcag cggcgaatta tttaggcatc
    36481 agccggacga cgttctggcg gcggctgaaa agctgaactg ccgaatgcag cgcgaacgct
    36541 ttatccggca taaatttcaa tagatgatca ccgataaact tacgcatcgg agatgtttac
    36601 ataggattca gaattacttc ttcttataaa tatttgccgt gccgtggatc ttattgtcag
    36661 tttgaccgga ggtcagtacc aacacatcag cccctttttc atccgctttt ttgatcaaat
    36721 cttcttttgc atctgcagtc gacatttcat tgctggttga aatatcacct attttttcat
    36781 actgcgattc aactttttca aattccgctt tggtcatcaa ttcagcggca tagacattgg
    36841 taacggctaa cgctaacgca ccgactaaca ttttagagat tattttcata ttacggctcc
    36901 agagttgtta tcacactatc acccacccac attattgggt tgattaataa ttagttcagt
    36961 cagggcataa acgccagtaa ccggaaataa gacactttgt gatctctctc gcacccgatt
    37021 atttttggta gaaatatgat gcagttagtt cacttattta tggatgaaat cactatggat
    37081 cctttgcatg ccgtttacct gaccgtagga ctgttcgtga ttactttttt taatccggga
    37141 gccaatctct ttgtggtagt acaaaccagc ctggcttccg gtcgacgcgc aggggtgctg
    37201 accgggctgg gcgtggcgct gggcgatgca ttttattccg ggttgggttt gtttggtctt
    37261 gcaacgctaa ttacgcagtg tgaggagatt ttttcgctta tcagaatcgt cggcggcgct
    37321 tatctcttat ggtttgcgtg gtgcagcatg cgccgccagt caacaccgca aatgagcaca
    37381 ctacaacaac cgattagcgc cccctggtat gtcttttttc gccgcggatt aattaccgat
    37441 ctctctaacc cgcaaaccgt tttatttttt atcagtattt tctcagtaac attaaatgcc
    37501 gaaacaccaa catgggcacg tttaatggcc tgggcgggga ttgtgctcgc atcaattatc
    37561 tggcgagttt ttcttagtca ggcgttttct ttgcccgctg tgcgtcgtgc ttatgggcgt
    37621 atgcaacgcg ttgccagtcg ggttattggt gcaattattg gtgtattcgc gctacgcctg
    37681 atttacgaag gggtgacgca gcggtgagca gataatttac tctctacgta atcaacctga
    37741 tttgccgaat cacggccatc ggcgatgata gcccccgtaa tgcgtggtcc ttatttccga
    37801 taagtttact tgagtcttta gcttcccatt tcagcccact ctcccctgtg tgggcttttt
    37861 tcattggtct gccccatcct gaatagccaa acaatggcaa tgttccactt tgcagggatg
    37921 ataataaggg gatctgattc agaagagttt tgaaaagttg gaccgccatc gaggcctcga
    37981 accccgtacc atacaacaat cctggttgtc gtctgctctt cctgatgagc taatggcggt
    38041 ttttgatatg agccttacag catattttct gtcaggcttg agtgcgatgc gtaagataca
    38101 gaaaagaccc cacacaaaca tgatggaatt atgatttttt tcatatgaat gtcaaccaac
    38161 acattcacaa aacatctgca tgagatcatt ttttatacac cgcatggctg cgaaaccact
    38221 actggtgctt ttttaagcga agtgtcgccg atcacaacaa aatatcggcg aaaaaagaga
    38281 tggaatgcca gttggcatac agatatacag atgaaatgat tacctgcatt gcgattcact
    38341 ctcaggtgga ataacaactt gcaggtggaa ccctttctga actaaagagt gtagcggatt
    38401 ttaacgtgct tatttacagg ataatatctg tcacctaatt cctgcactct attagatatc
    38461 cattcattta atcgcgcatc atctctgtat gtttttacgt ccagaacaga gagcaataac
    38521 atcaccagtg attcaggaaa aacagggtag atatttttta agtgtaataa taatccatgc
    38581 gcaagcgcct gcttaatggg cgcgtctgtc tccggaatag acgacatttc gcgaagccat
    38641 ttttccacat gcatacactc tttcccttta gggaaaattc tcagcaaagg catatggtat
    38701 tcaagaagaa tacatttgca atctgttcgc actgaatcga taaactgcac taatttctta
    38761 agcccggtaa agcgtccagc ctgcacgttt gctttaatat caagaaacgc atcatcctgg
    38821 tcatataccc aaactgtccc tttttgattt tcaagtatgc gaaaaacaaa cttaaccggg
    38881 tgatcagggt aatccatcca gtcataaaat ccagggaaat cattaaactg cacatttatg
    38941 gtgagtgcgt tatcgtctga ccactcacag tctcgtacgg cagccatgag atgaatgagt
    39001 ttgtcgtcat cgactaaatc atcacgacaa tcataaggat aatcataata ttgtttaatc
    39061 aaaaccttga atatatcgac acaggaaacc agggagcttt tgatatcctc tggtaactga
    39121 ttgtttttaa ccgtattaag tatgctttgt tgcgtatatg gcatcaaatt attgtgcgga
    39181 gcttttaatg atatcatcgc gatctctctt aaataaaaat aaacgtcgca gataataaag
    39241 ctctgattaa accaggcact atcagaaatc gctcataact aacgtgtgaa gtattgtgta
    39301 ctggagggcg ttaatttaac aatttaaatt tacgttatag gttttactgc tactttgata
    39361 ttatttcgct ctccttaact aaaaagttaa gtggagagcg aagttaatat gttaaaccac
    39421 agggtattta ttaatttttt cagtctgtta gtgtgcgatt atcgataaca aaacgatatt
    39481 tcacatcacc gcgcagcatt cgctcatagg cttcattaat ttgatcggcc cgaatcatct
    39541 ctatatcagc cacgatgcca tgttcggcgc aaaaatcgag catctcctga gtttctggaa
    39601 tgccgccaat catagaaccg gctatcgcac ggcgtttcat gatcaggttg aaaacttccg
    39661 gcgatttatg cggtgtcgca ggcgcaccaa ccagcgtcat ggtgccatca cgcttcagca
    39721 aggtggtaaa atcgtcgaga ttatgtggcg cagctactgt attcaaaatg aaatcgaaac
    39781 tcttcagatg agccgccatc tcatcggcat tgcgtgagtt aacaacttca tcggccccca
    39841 gggcttttgc cgcttcgcgt tttgcctcag aagtggtaaa tgccaccaca tgtgccccca
    39901 tcgcgtgggc cagcttaatc cccatatgtc ccagaccgcc gatgccgacc acgcccactt
    39961 ttttacccgg cccggcctgc cagtgacgta gcggcgaata cgtggtgatc cctgcacaca
    40021 acaaaggagc caccgccgcc agctgctctt gcgggtgacg aatacgcaga acatatcgct
    40081 catgaacgac gatctgttgt gagtagccgc ccagagtatg gcccggttcg tccggcgtcg
    40141 gcgagttata ggtgccggtc atgtgatcac agtagttttc caacccgtct tcacactctt
    40201 cgcaatgttt acaactgtcg acaatgcagc cgacaccgac cagatcgccc ggcgcatatt
    40261 tttctacctg atcaccaacg gctaccacac gccccacaat ttcatgaccc ggcacgcagg
    40321 ggtaaaccgt ccccgcccac tcggaacgga cctggtggag atcggaatgg caaacgccac
    40381 agtaagcgat ttcgattttg acatcattcg gtcccggttc acgccgggtg atatccatcg
    40441 gttcaagtgg ttgtttagcg gaatatgcac caacagcttt gatcttcatt gtgtttactc
    40501 ctgattagct atgtgtattt ggcaacgcct gatatgtcat cgcggcaaaa cgcgtccatt
    40561 gaatatagcc aatatttaaa ccacccgatc cagccccaac atgccgcgag cctgaatgaa
    40621 acagagcagc aacgttcccc ataaggcgag cgcctgtaag tgtgatattt gctatctgta
    40681 aaagactaaa atcggcaaaa ctgatgatct tttcacgtag acaaatagtt atctacacaa
    40741 cgtcaataag ggcatattcc tcaaagataa tgtccatttc tgccgacaca ctcatattca
    40801 gattgcccca ctccctgggg cttaaatctc ttactattca ccgttgcagg cgtttcaaat
    40861 gcgcatcaac ctgccacact cccccccacc agttgccctt tatggaacgt tgcggttctc
    40921 ggcgagatac gcgccaccgc ctcggcggaa caggaggcgt ccaccagcac aaagctggcg
    40981 tcatcctgcg cttttggcca tacacgctcg cctttttcat tcagcggcaa tacatcgcca
    41041 gtggctaaaa acagcgagcg ggagaggttc tgttcgttag gacgaatata gagctgcgcg
    41101 tacagattgg ctttttccag catgtcgccc agaccataag gcgaccagtg gtcgataacg
    41161 ctgccagtgc cagtcatcac ttttacgcct ttgtcgtgca actgtttgag cggcatatgc
    41221 agcgtgccaa tcggcaccgt cgaggcgata gaaatttgtt gcaccaccat ccggttcgcc
    41281 agttcatcta cctgttgctc gttgagcgtt gccagcgcaa aggcgtgact gatggtcagc
    41341 ttgcccttca gctgtggcgt tttctctacc gtttcaacca tataattgat ggctgccacg
    41401 cctgccggag tggtttcgtg caggtgaata tcgacgcctt tgtcgtagtc cagcgcaatc
    41461 tggaacatgg tgtcgaggga tttttccatc gcgccatcaa cactggtcgg gtccaggccg
    41521 ccgacgtaat gcgcccccgc ctgcatcgct tcacgcatta aaggttcaga tttcgacagc
    41581 agcaaaccgt gctgcgggaa ggcgacgatt tcacactcaa agcccgcctg acgtcgcgcc
    41641 agcaccgcct gcaaattttg cagatttttc aggccggaaa ccggttcgat attgcagtgg
    41701 ctgcgggcaa tggtggtgcc tttcgactgc aataaatcaa tcagtttttc tgcccgctcc
    41761 tgagtgtacg gttgcagttc cggcagcatt ttctgctcga gtttgatcat gtcctggatg
    41821 gtggtgcctg ccggacgatt gagcgagcgc cacggcccgc cgtaaaaggt tttgtcgaga
    41881 tgaatatgca tgtcgcgggt ggtgggcagc atcagcttac cgccagcgtc atagtgcggc
    41941 agcgtggcgt ccggatgcag cttgttctcg cgcagggcga caattttgcc gtcctgaatc
    42001 tccacggtct ggcgcgccgt gcgggtctgc accgccacgc cattttcgta gtcaaaaccg
    42061 gtttccagca gcacgttatc gagatagtaa tgcgggtcag tgattttcat ggtgttgttc
    42121 gcttcgcagt ttagggtgcc agctaccgcc gcatgggcga gcggcacaga ggtaccaaac
    42181 agcgcggcgg cggtgaccat cttaccgctc tggctcagaa attcacggcg gctattgctt
    42241 tctttcatct tacgtcctta cgttttaata atatgagtgc ccgtttcgcc gcgcagcgcc
    42301 gcaggcaggc attccggcgt ggtgataatc acttctttgc cgccttgttc taaaaatgtc
    42361 aggctggcga tgatttttgg caacatgctg ccgggcggga aatgcccttc ctgcatatag
    42421 cgggtcatgg tggcaatatc cacccgatcg agcgcctgct gctgcggttt gccaaagtga
    42481 atacacactt tttcgacgcc agtggtgatc acaagaatgt cggcgtgaat ttcacgggcc
    42541 agcagcgcgg tagagagatc tttgtcgata accgcgtcca cgctttggta atctcccgcg
    42601 tcagtacgca ctaccggaat tccaccgccg cccgcgccaa ttacgacaaa accttgttgg
    42661 atcagcgctt taatggcagg tgcttcgaca atacgtttcg gttccggcga ggcgaccacg
    42721 cggcgatagc cccgcccggc atcttcaaca aaacaccagt cagggtttgc cttttgtaat
    42781 tcgtcacgct ggctgtcact aaagaatgcg ccgatgggct tggtgggatg ggcaaaacct
    42841 ggatcgtttt tatccacttc cacctgagtc accacggtga cggctttctt ctcgccgtga
    42901 cgcgccagcc ggttattcag cgcctgttgg atcagatagc cgatgccgcc ctgcgtatct
    42961 gccacacagt tcgccagcgg cgttaagggc agcccttcgc gcttgtgggc aatctccgca
    43021 cggcgtaaat ccagcccgac ctgcggcccg ttgccgtggg tcagcacaat gtcgtaatcg
    43081 gaagccagca tttccagcac cgtatcggcg acggctttca ccgcctccgc ctgatgctca
    43141 atcgactggc tggcgttatc tttgataatg ctgttgccac caatggcaac gaccacaagc
    43201 tctttcatgt tgttatgtcc gctacagagg gtgatggggt tatgaccaac gccagactgc
    43261 ctgatgcgct acgcttatca ggcctacaat tctcgcgcca ctcgtaggcc ggataaggcg
    43321 ttcacgccgc atccggcaat ggtgacaaat gcctgatgcg ctacgcttat caggcctaca
    43381 gattctcgcg ccactcgtag gccggataag gcgtccacgc cgcatccggc agtggtggca
    43441 aatgcctgat gcgctacgct tatcaggcct acagattctt gcgccattcg taggccggat
    43501 aaggcgttca cgccgcatcc ggcaatggtg acaaatgcct gatgcgctac gcttatcagg
    43561 cctacagatt cttgcgccat tcgtaggccg gataaggcgt tcacgccgca tccggcatga
    43621 acatgtaggt cagacgccgt aacgttcgca ccagccaaga atggctttct cgaagcaggc
    43681 aaaaggtgga tgcacaatgc ccgcgccaat catgccgacg cccgcatctt tatgggcgat
    43741 ggcggtgttg atcaccggca gaatgccgct gctacccacg cgggtgatgt cgattgccga
    43801 cggcacgccc ataaaaccga gcagcggaat ggtgacgttg gggttttcac cgagggtgat
    43861 ttcgcgcatc tgacgggaga aatcaatagc ttcttccacc gtgccgccca ccagcgcgac
    43921 gatagcgggc gcggtcgcca tagcaaatcc gccaataccg taggtttcgg tgatggcgct
    43981 gtcgccgata tccagccccg aatcttccgg cttataaccg gcaaacatcg ggccgatcac
    44041 ctgctgcgcc gggccggtaa accattgccc cggcaggccg ctgacccgca ggccgaactc
    44101 gacgccgtta cgcgccatgg tggtgaccac ggtgctgtat tcgatgccat gcgccgcatc
    44161 catcgccgct ttacacatcg ccatccacgt cgggccggag aagtagtcgc tgctggcgac
    44221 aaactcaaac acttcgcgct gttgctcgac ggaataaccc gcctgaataa tccccggcgt
    44281 cagcgcctga atcagcagtg tcgtcccggc gttattgcgg ttatggcact catcgcccat
    44341 atgcagcgcc tgcgccagca ttaagcgcag atcgatttcg ccgataattt tcatcgcgtc
    44401 gcgcagtatt ggtccctgca catcacgcat ccagttcagg cggtcaatca cgctctggtc
    44461 gttagcgccc atacgcaaaa tcttcaccat ctgctcgctc atgttggtat aagcgatgtt
    44521 gccgtaggtt ttgtttttta cgatgtgcat aaacatcgag gccgaggtaa cacccgccat
    44581 cgatcccacg cagtcgtgct cgtgacacgg cgagaaggtg atctccccgg aagccgccag
    44641 ttcagccgcc tcgtcgagat ctttcgccag tccttcgaac accagcgctc cggtgaccgc
    44701 gcctttcatc gcgccgcaca ttttttccca ggtgatcggc ggcccggcgt gaagaatggt
    44761 tttcgccgtc atgcccggca ccacgttaat cgcctgatca aaaccaatca gcaccggatg
    44821 cgactggata atacgctcca gcgcctgctg gttagcggcg gcgattttgt ccgccagcgg
    44881 cgaatcggca atgttatcca gcgcctgcac cacctgcata ttgccctgcc ccggcggcgt
    44941 ccagtcgagt tgagtcactt ctacatgctg ctttttcagg tcatcgctaa acatggcgat
    45001 gccgacgtta ataacgttca atggttggct aaacagtgac tggctcatca ggcttcctcc
    45061 cctttgcaga taaattcacg cgccagcaat ccggtattgg tgctgctgct cgccagaatc
    45121 actccggcat caagcagcat ctggctttgt tgttctaacg atggcgtatc aagatcggta
    45181 cccagcacat aggcgagaat gatcaactcg cgtccttcgg cagcggcgat cgctttcgct
    45241 tctttgatcg tctcgatggt ggagccgacc ggatcttcat gcgatccaaa tccgagcaca
    45301 aaatccatca cgatcaccgc cacttctgga tcgcgcgcct cttcgatcaa gcgactgatg
    45361 cggttggtgg ggtcaatcat cgggtgcggc ttgccgttgg tgaagtcgtc atcgccaaag
    45421 tcgaggaagg tgtgtttgat gctgcggttg atatctttca ggcggaattc cggatcgggc
    45481 tgaatgttgc tgtagacatc gccatgtttt tccatcaccg cgaacatggt ttcgtcgcac
    45541 agcgtgccgc cgcagaacag gccacgaatg tatttctgct gcggttgcag acgcgcacgc
    45601 acatccgcaa tcaacggctg gttaagcgta tgcaggtcga gattttcctg tttcacgccg
    45661 gagagcatca ccgcttttag cgctgcctct ttggtgccgc gggcaaactg tagcccctgc
    45721 tcatctactg gcgtttcgcc acgatcgagg aagcagacga ccaccggctt gcggcaggcg
    45781 cgcgcacgtt ccagcacttt gcgggccacc gcaggcgcag gcggtttgga gataagcgca
    45841 atgatttcag tttgcggatc gttttccagc atcccgatgg cgtcgagcat catcaggccg
    45901 ccgattttct cgctcaggtc gcgcccgccg gtgccaatca gttgcgaaac gccgccgcca
    45961 aattcatgaa tgcggacgct caactcctga ctgccggtgc cggatgcgcc aacaataccg
    46021 atgttgccgc gacgcacggc gttaccaaaa cagagcgccg cgccgttgat aatcgccgtg
    46081 ccacagtctg gccccatcat cagcagccct ttttcgtggg ccagttgctt gagcgccagt
    46141 tcatcttcaa ctgagacgtt atcggaaaac agcatcacgt tgagatcgtt ttgcagcgcc
    46201 tgacgcgctt cgcgagcggc aaacagaccg ttgaccgaaa tcaccgccag gttactttcc
    46261 gggatatgct ttttggcgct gccaatagtg gcgtaacgcg cctcgtgcga gccgctttgc
    46321 gctttggtgt tgaacagttc ttcaatctcc accagtaact gctcgttgtc cgcacccgat
    46381 ttaccattga tgacaatcat caggtcgccg tttttcgcct gctccagctc cggcgtcagc
    46441 agtcctaaat tcttcagcac gcctttattc atttcggtcg ccatcgccac aaatgcctgc
    46501 tcgacgccgt cgagtttatt tgcacgcgtg gagatagaca tcagcgagac agaatcaaaa
    46561 taggtattcg gtttaatgac tattttaact gacataattc cctccgtagg tttggctcag
    46621 cgcacaacca tcggccatgc catacagcat gtcgcagccg gaactggagc caatatgttt
    46681 aattttttct attgcctgag ttgcgttctc agggatgtca taaataatgt tgtgaataaa
    46741 acgatgaata ttttcccggc agcgttgttg taatgcggct tccagcgtta tggcacttaa
    46801 taatgtggta ttatttttgc cgcgttgcag accgagataa aattcctctt tgtatttttc
    46861 cgccggatgc ccgggaataa ataaaataag cgccagacct gttaaataat cgtcggctga
    46921 tggcgtaagg ccaatcccta accccatcat actggcgacc gctgaggcga tattttgttt
    46981 atcgtttacg gcctgaataa ctgcccgtcg tttaatatgt aattctttat ttaacgcctg
    47041 ataaaacgga ttatcgccgc gataattaaa cagggtttca ttttccccca ggtgctgatg
    47101 aataatgtcg tgccactgta gccaggcgat aaggtgaaaa ttcacagcgg tcatttgcaa
    47161 ggttggggac agccaacgcc gacaacgact catctctata tgaagatgtt gaccaaccgt
    47221 aataccttga tcgtcaaact gaaccttatc accatgccgg aacagatcat caaagtgagt
    47281 gagtgccaac cgacaactgt ttggcgcatt gtcgtactct tcacaaagca gcgtcagcaa
    47341 ctgctggcga gccgggagtg cgatatttac cgctctggca aagacctgtt caacctgtcc
    47401 ttgcccccgc tgcgccagaa aatccgcatc cgcagttagc gcccacacac accgtctttc
    47461 tggtgtgttg atagcaagcc tcccggttta tgcacctgcg gcaatcagta actgcgcaat
    47521 ctcttcaaag ccccgttccc gcgccagttc cagtggcgtt ttgccatatt tatcggtcag
    47581 atgcgggctg gcaccgtgtt ccagcaataa ctgcacaatc gcctgctgtt taataccacc
    47641 atcattaagc acaatcgctt ccagtagcgg cgtccagcct acatggttgg tctggttaac
    47701 gttaatctcc gtatgcgcca aaagctcttt tacaatactt aaatggcctt tttcacaggc
    47761 aggcgtcagg ccgacaccgc caaaacgggt tacgcaatta agatcgggtt tagccggtaa
    47821 aataattcgt agtagcgtta aatcatcgtt cagacagcta attaaaaaag gatttaaaca
    47881 ggtatgatct tgcttattaa tatccgctcc ggcatcaatt aatgcctgaa cgcaagcata
    47941 ttgctgatat aaacttgcca gcgtaattgc cgttttcccc tgacgatcgc aggtattaat
    48001 atcgacaccc agcgcaaggc aggtttttac tttatcgata tcaccctgtt gtgcagccaa
    48061 taaatagtcg gcaggtagat tttttatact cattcacatt cccctggttt ttgtggctgt
    48121 tttcgatgaa ttgagaatag caacgataat ctgataaaag aacccgctta aatttaattc
    48181 gccgtatctc gcctttttgt tgaataatat tcaacaatct tttcgcagtg tgcggtagtg
    48241 caatatttgt ttctttgacc cgataccctt tcactcaatc aggttttatt tctctatagt
    48301 ctgcacatgt aagagtagct ttcgtccatg tctaaccaga ggggaacaag atgaacggac
    48361 tcacggcaac gggtgtcacc gtcggtattt gtgcagggct ttggcagtta gtgtcttcac
    48421 atgtcgggct ctctcaagga tgggaattat taggaaccat tggcttcgtc gccttttgca
    48481 gtttttatgc cgcaggcggc ggtaaatcgg ggtttatcag aagtctggcg gttaattatt
    48541 ccgggatggt gtgggcgttt ttcgccgcgc tgactgctgg ttggctggcc tctgtaagtg
    48601 gactgtccgc gttctgggcg agcgtaatta ctaccgtacc cttctcggcg gtagtggtct
    48661 ggcaagggcg tttctggtta ctgtccttta ttcccggtgg ctttctcggc atgacgctgt
    48721 tttttgccag cgggatgaac tggacggtga cgttactggg ttttctggcg ggtaactgcg
    48781 tgggggtaat ttcagaatat ggtggacaaa aattaagcga agcgacgact aaacgcgacg
    48841 ggtattaaaa gttattcaaa aatgattatc tatctttaac cgatacctct acagtcatag
    48901 ctggagaaat tcatagtaga taatggcgag aatggtttaa tgaactcaat ttttaccgaa
    48961 gagaatctgt tggcatttac taccgctgcg cgttttggca gcttcagtaa agccgcagaa
    49021 gagttgggtt taaccacttc cgccattagc tacaccatta agcgtatgga gacggggctg
    49081 gatgtggtgc tgttcactcg cagtacccgc agcattgagt taacggagtc cgggcgttat
    49141 tttttccgca aagctaccga cctgctgaat gatttttatg ccatcaaacg cagtatcgat
    49201 actatttcgc agggcataga agcgcgtgtg cgcatttgta ttaatcagct gctttatacg
    49261 cccaaacaca ccgcacgctt gttacaggtg ctgaaaaagc agtttcctac ctgccagatt
    49321 accgtcacca ccgaagtgta taacggcgtc tgggatgcga ttattaataa tcaggccaat
    49381 atcgccatcg gcgcacccga tacactactg gacggcggcg gtattgatta cactgaaatt
    49441 ggcgcgattc gctgggcttt tgctatcgcc ccggatcacc cgttagcctt tgtgccggaa
    49501 cccatcgccg aaagccaact gcgtctctac cctaatatta tggtggagga caccgcgcat
    49561 acgattaata aaaaagtggg ctggttgctg cacgggcagg agtcaattct ggtgccagat
    49621 ttcaacacca aatgtcagtg ccagatttta ggtgaaggaa ttggtttttt gccggattac
    49681 atggtccgtg aggcgatgac gcaatccctg ctggttaccc gacaaatcca taatccgcgc
    49741 caggattcgc gcatgttact ggcgactcag cattctgcta cgggtcaggt gacgcagtgg
    49801 attaaaaaac aatttgcgcc aaatggcata ttaacgggga tctatcagga tttactgcat
    49861 cgggagaatt aatcgctgcc aacctcccga tgcgctgtga atagcggttt acatcaacca
    49921 cctgctttca ttacccattc agagataaat ttattacccg gtactggcgg agagtacaaa
    49981 tagccctgca aaaagtgaac gcctttaccg atcattaaat ccgcctgctc ctgggtttct
    50041 accccttccg ccacgatact cagaccaggc ttacgcgcta gttcgacaat attgtccaca
    50101 atatgaccgg agatttcgtc gacactcgcc atttgcacaa atgacttatc gatcttaata
    50161 aaatcgaccg ggaacgcctg caagtaacga taggtcgcat aacccgtacc aaagtcatcc
    50221 agcgcaaagg taatgttgtg ctgatgaagg ctgtcaaata tcgctctggc ttctggcgtt
    50281 accggaatag ggttacgttc cgttagctcg agaaccagct tgattttatc gttacctaat
    50341 ttattaacca ggttcagaca ctctttttca aatcccgctg ccaaaaaaca acccgccgag
    50401 acgttgatgc caatatggaa attgtccggc agcaaatgtt ttaccggcat cagaatatcc
    50461 gcagtctgtt tcatcagttg gcgggtcatt atgacaataa gaccggatga ctccgccaga
    50521 ggaataaact gatccggtgg gataattccc gtttgtggat gttcccagcg gacaagcacc
    50581 tcacagcccg tcagtacccc agtctgcgcg cagaaaaccg gttggatcca cggtttgaat
    50641 tcgtggtttt ccaacgccag actgatggct tcaggcgtga cgatatggtg atagtgatta
    50701 tcattaatat atctgtgact attactcccc gtggcggata tgatctccgg attgtactga
    50761 aagaaaatat cgcgccagaa agtaatatcg ctctgaatcc ccagtttctc aaagagctgt
    50821 ttcttttgat gtgaaattgt ctttgcactg cgatttctgt actgtgatat ttctgttaca
    50881 gacattccct gcatcagcag cttgagtagc agtcgttctt tctcggatac gctaccaggc
    50941 aatgacaaat gaaccgttgt accgaactct tgcagaaaaa cacgaaaatc acatgaattc
    51001 atgaacacac ctttatcttt tatcgctgtt cagtatgagt gattacctgt cgattcctga
    51061 gcacacataa ggggtaacca taaacatcag cgatgccata cgtataacat cccacatcac
    51121 tatcaagaag attatcttta cctctgatgc tcgctcaaaa acagttacgc taaatacctt
    51181 aaaaaggtaa tcacaagtca aactcaggag ataatcacgc aagaatgcaa tattaaaatt
    51241 cagatactca tttttggtaa taaagaagta gttggactat ttcaatattt ataatttccc
    51301 actacatact ggcatccatt catgagcaaa ggcgcattat atgaatttaa caatccagat
    51361 caactgaaaa tacctctccc tcataaacac atagcgtcaa cattcaatga cataatgagt
    51421 aaagatgttg gttatgcata cgtatcatta ctctatgcct gtcccttaaa aacccactca
    51481 ttaagactga atccattcag c
//
LOCUS       DAPOAV010000024        48971 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.024, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000024 DAPOAV010000000
VERSION     DAPOAV010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 48971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48971
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.024"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(379..1575)
                     /gene="hemY"
                     /locus_tag="RN951_001659"
     CDS             complement(379..1575)
                     /gene="hemY"
                     /locus_tag="RN951_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX biogenesis protein HemY"
                     /protein_id="HDX2526672.1"
                     /translation="MLKVLLLFVLLIAGIVVGPMIAGHQGYVLIQTDNYNIETSVTGL
                     AIILILAMVVLFAIEWLLRRIFRTGAHTRGWFVGRKRRRARKQTEQALLKLAEGDYQQ
                     VEKLMAKNADHAEQPVVNYLLAAEAAQQRGDEARANQHLERAAELAGNDTIPVEITRV
                     RLQLARNENHAARHGVDKLLEVTPRHPEVLRLAEQAYIRTGAWSSLLDIIPSMAKAHV
                     GDEEHRAMLEQQAWIGLMDQARADNGSEGLRNWWKNQSRKTRHQVALQVAMAEHLIEC
                     DDHDTAQQIIIDGLKRQYDDRLLLPIPRLKTNNPEQLEKVLRQQIKNVGDRPLLWSTL
                     GQSLMKHGEWQEASLAFRAALKQRPDAYDYAWLADALDRLHKPEEAAAMRRDGLMLTL
                     QNNPPQ"
     gene            complement(1578..2759)
                     /gene="hemX"
                     /locus_tag="RN951_001660"
     CDS             complement(1578..2759)
                     /gene="hemX"
                     /locus_tag="RN951_001660"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HDX2526673.1"
                     /translation="MTEQEKTSAVVEETREAVDTTSQPVATEKKSKNNTALILSAVAI
                     AIALAAGIGLYGWGKQQAVNQTATSDALANQLTALQKAQESQKAELEGIIKQQAAQLK
                     QANRQQETLAKQLDEVQQKVATISGSDAKTWLLAQADFLVKLAGRKLWSDQDVTTAAA
                     LLKSADASLADMNDPSLITVRRAITDDIASLSAVSQVDYDGIILKLNQLSNQVDNLRL
                     ADNDSDGSPMDSDGEELSSSISEWRINLQKSWQNFMDNFITIRRRDDTAVPLLAPNQD
                     IYLRENIRSRLLVAAQAVPRHQEETYRQALENVSTWVRAYYDTDDATTKAFLDEVDQL
                     SQQNISMDLPETLQSQAMLEKLMQTRVRNLLAQPAAGTTEAKPAPAPQADTPAAAPQG
                     E"
     gene            complement(2781..3521)
                     /gene="hemD"
                     /locus_tag="RN951_001661"
     CDS             complement(2781..3521)
                     /gene="hemD"
                     /locus_tag="RN951_001661"
                     /EC_number="4.2.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="HDX2526674.1"
                     /translation="MSILVTRPSPAGEELVSRLRTLGQVAWHFPLIEFSPGQQLPQLA
                     DQLAALGESDLLFALSQHAVAFAQSQLHQQDRKWPRLPDYFAIGRTTALALHTVSGQK
                     ILYPQDREISEVLLQLPELQNIAGKRALILRGNGGRELIGDTLTARGAEVTFCECYQR
                     CAIHYDGAEEAMRWQAREVTMVVVTSGEMLQQLWSLIPQWYREHWLLHCRLLVVSERL
                     AKLARELGWQDIKVADNADNDALLRALQ"
     gene            complement(3518..4459)
                     /gene="hemC"
                     /locus_tag="RN951_001662"
     CDS             complement(3518..4459)
                     /gene="hemC"
                     /locus_tag="RN951_001662"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HDX2526675.1"
                     /translation="MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTR
                     GDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICERE
                     DPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLD
                     NGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAA
                     LNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGER
                     RGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA"
     gene            4846..7392
                     /gene="cyaA"
                     /locus_tag="RN951_001663"
     CDS             4846..7392
                     /gene="cyaA"
                     /locus_tag="RN951_001663"
                     /EC_number="4.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I adenylate cyclase"
                     /protein_id="HDX2526676.1"
                     /translation="MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHY
                     HHPLMPGYLDGNVPKGICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMG
                     STSSVGQSCSSDLDIWVCHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENR
                     FRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTL
                     YAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYP
                     NPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVC
                     EKLSRERACVGWRRAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQ
                     SYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLT
                     FIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLY
                     IKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAF
                     RNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTIL
                     GKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVS
                     GQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNHVKLPAVVDGFASEG
                     IIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGS
                     SFINFNLPQFYQIVKVDGREQVIPFRTKSIGNMPPANQDHDTPLLQQYFS"
     gene            complement(7432..7752)
                     /gene="cyaY"
                     /locus_tag="RN951_001664"
     CDS             complement(7432..7752)
                     /gene="cyaY"
                     /locus_tag="RN951_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron donor protein CyaY"
                     /protein_id="HDX2526677.1"
                     /translation="MNDSEFHRLADQLWLTIEERLDDWDGDSDIDCEINGGVLTITFE
                     NGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWICDRSGETFWDLLEQAATQQAGET
                     VSFR"
     gene            8215..8418
                     /locus_tag="RN951_001665"
     CDS             8215..8418
                     /locus_tag="RN951_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDX2526678.1"
                     /translation="MKNVFKALTVLLTLFSLTGCGLKGPLYFPPADKNAPPPTKPVET
                     QTQSTVPDKNDRATGDGPSQVNY"
     gene            8455..9279
                     /gene="dapF"
                     /locus_tag="RN951_001666"
     CDS             8455..9279
                     /gene="dapF"
                     /locus_tag="RN951_001666"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HDX2526679.1"
                     /translation="MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGVGFDQ
                     LLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANG
                     RMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHC
                     VIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACG
                     SGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL"
     gene            9276..9983
                     /locus_tag="RN951_001667"
     CDS             9276..9983
                     /locus_tag="RN951_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF484 domain-containing protein"
                     /protein_id="HDX2526680.1"
                     /translation="MKQPGEELQETLTELDDRAVVDYLIKNPEFFIRNARAVEAIRVP
                     HPVRGTVSLVEWHMARARNHIHVLEENMALLMEQAIANEGLFYRLLYLQRSLTAASSL
                     DDMLMRFHRWARDLGLAGASLRLFPDRWRLGAPSNHTHLALSRQSFEPLRIQRLGQEQ
                     HYLGPLNGPELLVVLPEAKAVGSVAMSMLGSDADLGVVLFTSRDASHYQQGQGTQLLH
                     EIALMLPELLERWIERV"
     gene            9980..10876
                     /gene="xerC"
                     /locus_tag="RN951_001668"
     CDS             9980..10876
                     /gene="xerC"
                     /locus_tag="RN951_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HDX2526681.1"
                     /translation="MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENG
                     LQSWQQCDVTMVRNFAVRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVS
                     APKAPRHLPKNIDVDDMNRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHL
                     DLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRDLFGSEDDALFLSKLGKRISAR
                     NVQKRFAEWGIKQGLNNHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYT
                     HLDFQHLASVYDAAHPRAKRGK"
     gene            10876..11592
                     /gene="yigB"
                     /locus_tag="RN951_001669"
     CDS             10876..11592
                     /gene="yigB"
                     /locus_tag="RN951_001669"
                     /EC_number="3.1.3.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(5-phospho-D-ribitylamino)uracil
                     phosphatase YigB"
                     /protein_id="HDX2526682.1"
                     /translation="MRFYRPLGRISALTFDLDDTLYDNRPVILRTEREALTFVQNYHP
                     ALRSFQNEDLQRLRQAVREAEPEIYHDVTRWRFRSIEQAMLDAGLSAEEASAGAHAAM
                     INFAKWRSRIDVPQQTHDTLKQLAKKWPLVAITNGNAQPELFGLGDYFEFVLRAGPHG
                     RSKPFSDMYFLAAEKLNVPIGEILHVGDDLTTDVGGAIRSGMQACWIRPENGDLMQTW
                     DSRLLPHLEISRLASLTSLI"
     gene            11676..13838
                     /gene="uvrD"
                     /locus_tag="RN951_001670"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
     CDS             11676..13838
                     /gene="uvrD"
                     /locus_tag="RN951_001670"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase II"
                     /protein_id="HDX2526683.1"
                     /translation="MDVSYLLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIA
                     WLMSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHH
                     MDANLPQDFQILDSEDQLRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQ
                     SYGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNIL
                     VDEFQDTNNIQYAWIRLLAGDTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAET
                     IRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGADGEPISLYCAFNELDEARFVV
                     NRIKTWQDNGGALAECAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDAL
                     SYLRLIANRNDDAAFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQACRELLQEKAL
                     AGRAASALQRFMELIDALAQETADMPLHVQTDRVIKDSGLRTMYEQEKGEKGQTRIEN
                     LEELVTATRQFSYNEEDEDLMPLQAFLSHAALEAGEGQADTWQDAVQLMTLHSAKGLE
                     FPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKE
                     VYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMGTPMVENDSGYKLGQRVRHAKFG
                     EGTIVNMEGSGEHSRLQVAFQGQGIKWLVAAYARLESV"
     gene            complement(13985..14749)
                     /locus_tag="RN951_001671"
     CDS             complement(13985..14749)
                     /locus_tag="RN951_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiester glycosidase family protein"
                     /protein_id="HDX2526684.1"
                     /translation="MAHQLLIGKGMITLNLKRIFLALTLLPLFAVAADDCALSDPTLT
                     VQAYTVNPQTERVKMYWQKANGEAWGTLHALLADINSQGQVQMAMNGGIYDESYAPLG
                     LYIENGQQKVALNLASGEGNFFIRPGGVFYVAGDKVGIVRLDAFKTSKEIQFAVQSGP
                     MLMENGVINPRIHPNVASSKIRNGVGINKHGNAVFLLSQQATNFYDFACYAKAKLNVE
                     QLLYLDGTISHMYMKGGAIPWQRYPFVTMISVERKG"
     gene            15119..16069
                     /gene="corA"
                     /locus_tag="RN951_001672"
     CDS             15119..16069
                     /gene="corA"
                     /locus_tag="RN951_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="HDX2526685.1"
                     /translation="MLSAFQLENNRLTRLEVEESQPLVNAVWIDLVEPDDDERLRVQS
                     ELGQSLATRPELEDIEASARFFEDDDGLHIHSFFFFEDAEDHAGNSTVAFTIRDGRLF
                     TLRERELPAFRLYRMRARSQSMVDGNAYELLLDLFETKIEQLADEIENIYSDLEQLSR
                     VIMEGHQGDEYDEALSTLAELEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQARE
                     ILRDIESLLPHNESLFQKVNFLMQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSY
                     GMNFEFMPELKWSFGYPAAIIFMILAGLAPYLYFKRKNWL"
     gene            complement(16112..16492)
                     /locus_tag="RN951_001673"
     CDS             complement(16112..16492)
                     /locus_tag="RN951_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2628 domain-containing protein"
                     /protein_id="HDX2526686.1"
                     /translation="MSKEYMNDGSLSEKWKYRFNFYDQHGFPGFWGATPEYKAAFKAL
                     KVRQRLTIQMNFIAFFCSWIYLFVLGLWKKAIIVLLLGILSLFVGALIGVNILGIAVA
                     AYVAVNTNKWFYEKEVKGLNTWSL"
     gene            complement(16506..16922)
                     /locus_tag="RN951_001674"
     CDS             complement(16506..16922)
                     /locus_tag="RN951_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709624.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526687.1"
                     /translation="MLTGDSYKDVKFMLRIFIPTSNGKISRRRYIFSFILINFIFAFL
                     IIFFNDGEAGFLVIVSTIVLHYLVINMNCQRLRDSGFIYIKTYVFGTLAVYIISIITM
                     IAEDFACSGNGSMIFLICYFSTFSMLMLAPTDSSKQ"
     gene            complement(16981..17871)
                     /gene="rarD"
                     /locus_tag="RN951_001675"
     CDS             complement(16981..17871)
                     /gene="rarD"
                     /locus_tag="RN951_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter RarD"
                     /protein_id="HDX2526688.1"
                     /translation="MDAKQTRQGVLLALAAYFIWGIAPAYFKLIYYVPADEILTHRVI
                     WSFFFMVVLMSICRQWSYLKTLIQTPQKIFMLAVSAVLIGGNWLLFIWAVNNHHMLEA
                     SLGYFINPLVNIVLGMIFLGERFRRMQWLAVILAICGVLVQLWTFGSLPIIALGLAFS
                     FAFYGLVRKKIAVEAQTGMLIETMWLLPVAAIYLFAIADSSTSHMGQNPMSLNLLLIA
                     AGIVTTVPLLCFTAAATRLRLSTLGFFQYIGPTLMFLLAVTFYGEKPGADKMVTFAFI
                     WVALAIFVMDAIYTQRRTSK"
     gene            complement(17923..18390)
                     /locus_tag="RN951_001676"
     CDS             complement(17923..18390)
                     /locus_tag="RN951_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312777.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HDX2526689.1"
                     /translation="MSAVLTAEQALKLVGEMFVYHMPFNRALGMELERYEKEFAQLAF
                     KNQPMMVGNWAQSILHGGVIASALDVAAGLVCVGSTLTRHETISEDELRQRLSRMGTI
                     DLRVDYLRPGRGERFTATSSLLRAGNKVAVARVELHNEEQLYIASATATYMVG"
     gene            18555..19424
                     /gene="pldA"
                     /locus_tag="RN951_001677"
     CDS             18555..19424
                     /gene="pldA"
                     /locus_tag="RN951_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase A"
                     /protein_id="HDX2526690.1"
                     /translation="MRTLQGWLLPVFMLPMAVYAQEATVKEVHDAPAVRGSIIANMLQ
                     EHDNPFTLYPYDTNYLIYTQTSDLNKEAIASYDWAENARKDEVKFQLSLAFPLWRGIL
                     GPNSVLGASYTQKSWWQLSNSEESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGY
                     NHDSNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVVGNTDDNPDITKYMGYYQLK
                     IGYHLGDAVLSAKGQYNWNTGYGGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQ
                     TRVGVGVMLNDLF"
     gene            19557..21386
                     /gene="recQ"
                     /locus_tag="RN951_001678"
     CDS             19557..21386
                     /gene="recQ"
                     /locus_tag="RN951_001678"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026263.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HDX2526691.1"
                     /translation="MAQAEVLNLESGAKQVLQETFGYQQFRPGQEEIIDTVLSGRDCL
                     VVMPTGGGKSLCYQIPALLLNGLTVVVSPLISLMKDQVDQLQANGVAAACLNSTQTRE
                     QQLEVMTGCRTGQIRLLYIAPERLMLDNFLEHLAHWNPVLLAVDEAHCISQWGHDFRP
                     EYAALGQLRQRFPTLPFMALTATADDTTRQDIVRLLGLNDPLIQISSFDRPNIRYMLM
                     EKFKPLDQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRA
                     DVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPA
                     EAMLFYDPADMAWLRRCLEEKPQGQLQDIERHKLNAMGAFAEAQTCRRLVLLNYFGEG
                     RQEPCGNCDICLDPPKQYDGSTDAQIALSTIGRVNQRFGMGYVVEVIRGANNQRIRDY
                     GHDKLKVYGMGRDKSHEHWVSVIRQLIHLGLVTQNIAQHSALQLTEAARPVLRGESSL
                     QLAVPRIVALKPKAMQKSFGGNYDRKLFAKLRKLRKSIADESNVPPYVVFNDATLIEM
                     AEQMPITASEMLSVNGVGMRKLERFGKPFMALIRAHVDGDDEE"
     gene            21450..22070
                     /gene="rhtC"
                     /locus_tag="RN951_001679"
     CDS             21450..22070
                     /gene="rhtC"
                     /locus_tag="RN951_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine export protein RhtC"
                     /protein_id="HDX2526692.1"
                     /translation="MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLG
                     ITCGVMVWAGIALLGLHLIIEKMAWLHTLIMVGGGLYLCWMGYQMLRGALKKEAVSAP
                     APQVELAKSGRSFLKGLLTNLANPKAIIYFGSVFSLFVGDNVGTTARWGIFALIIVET
                     LAWFTVVASLFALPQMRRGYQRLAKWIDGFAGALFAGFGIHLIISR"
     gene            complement(22132..22752)
                     /gene="rhtB"
                     /locus_tag="RN951_001680"
     CDS             complement(22132..22752)
                     /gene="rhtB"
                     /locus_tag="RN951_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine/homoserine lactone efflux protein"
                     /protein_id="HDX2526693.1"
                     /translation="MTLEWWFAYLLTSIILSLSPGSGAINTMTTSLNHGYRGAVASIA
                     GLQTGLAIHIVLVGVGLGTLFSRSVIAFEVLKWAGAAYLIWLGIQQWRAAGAIDLKSL
                     ASTQSRRHLFQRAVFVNLTNPKSIVFLAALFPQFIMPQQPQLMQYIVLGVTTIVVDII
                     VMIGYATLAQRIALWIKGPKQMKALNKIFGSLFMLVGALLASARHA"
     gene            22863..23885
                     /gene="pldB"
                     /locus_tag="RN951_001681"
     CDS             22863..23885
                     /gene="pldB"
                     /locus_tag="RN951_001681"
                     /EC_number="3.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipase L2"
                     /protein_id="HDX2526694.1"
                     /translation="MFQQQKDWETRENAFAAFTMGPLTDFWRQRDEAEFTGVDDIPVR
                     FVRFRAQHHDRVVVICPGRIESYVKYAELAYDLFHLGFDVLIIDHRGQGRSGRLLADP
                     HLGHVNRFNDYVDDLAAFWQQEVQPGPWRKRYILAHSMGGAISTLFLQRHPGVCDAIA
                     LTAPMFGIVIRMPSFMARQILNWAEAHPRFRDGYAIGTGRWRALPFAINVLTHSRQRY
                     RRNLRFYADDPTIRVGGPTYHWVRESILAGEQVLAGAGDDATPTLLLQAEEERVVDNR
                     MHDRFCELRTAAGHPVEGGRPLVIKGAYHEILFEKDAMRSVALHAIVDFFNRHNSPSG
                     NRSTEV"
     gene            23893..24693
                     /gene="yigL"
                     /locus_tag="RN951_001682"
     CDS             23893..24693
                     /gene="yigL"
                     /locus_tag="RN951_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar/pyridoxal phosphate phosphatase YigL"
                     /protein_id="HDX2526695.1"
                     /translation="MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGR
                     HHVDVGQIRDNLEIKSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDII
                     TNVYRDDEWFMNRHRPEEMRFFKEAVFQYALYEPGLLEPEGVSKVFFTCDSHEQLLPL
                     EQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMND
                     AEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNADDAVPHYLRKLYLS"
     gene            24769..25668
                     /gene="bioP"
                     /locus_tag="RN951_001683"
     CDS             24769..25668
                     /gene="bioP"
                     /locus_tag="RN951_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter"
                     /protein_id="HDX2526696.1"
                     /translation="MALLIITTILWAFSFSFYGEYLAGHVDSYFAVLVRVGLAALVFL
                     PFLRTRGNSLKTVGLYMLVGAMQLGVMYMLSFRAYLYLTVSELLLFTVLTPLYITLIY
                     DIMSKRRLRWGYAFSALLAVIGAGIIRYDQVTDHFWTGLLLVQLSNITFAIGMVGYKR
                     LMETRPMPQHNAFAWFYLGAFLVAVIAWFLLGNAQKMPQTTLQWGILVFLGVVASGIG
                     YFMWNYGATQVDAGTLGIMNNMHVPAGLLVNLAIWHQQPHWPTFITGALVILASLWVH
                     RKWVAPRSSQTADDRRRDCALSE"
     gene            complement(25556..26509)
                     /gene="metR"
                     /locus_tag="RN951_001684"
     CDS             complement(25556..26509)
                     /gene="metR"
                     /locus_tag="RN951_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MetR"
                     /protein_id="HDX2526697.1"
                     /translation="MIEVKHLKTLQALRNCGSLAAAAATLHQTQSALSHQFSDLEQRL
                     GFRLFVRKSQPLRFTPQGEILLQLANQVLPQISQALQACNEPQQTRLRIAIECHSCIQ
                     WLTPALENFHKNWPQVEMDFKSGVTFDPQPALQQGELDLVMTSDILPRSGLHYSPMFD
                     YEVRLVLAPDHPLAAKTRITPEDLASETLLIYPVQRSRLDVWRHFLQPAGVSPSLKSV
                     DNTLLLIQMVAARMGIAALPHWVVESFERQGLVVTKTLGEGLWSRLYAAVRDGEQRQP
                     VTEAFIRSARNHACDHLPFVKSAERPTYDAPTVRPGSPARL"
     gene            26746..29007
                     /gene="metE"
                     /locus_tag="RN951_001685"
     CDS             26746..29007
                     /gene="metE"
                     /locus_tag="RN951_001685"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HDX2526698.1"
                     /translation="MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELR
                     ARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPARHQNKDGSVDIDTLFRIGRG
                     RAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLDEVDEALALGHKVKPV
                     LLGPVTWLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELP
                     QAWLDAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAEL
                     HKRLPSDWLLSAGLINGRNVWRADLTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSV
                     ETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSAPIQARRHSTRVHNPAV
                     EKRLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKG
                     NLDANNYRTGIAEHIKQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGW
                     VQSYGSRCVKPPIVIGDISRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPRE
                     DVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEA
                     FRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDY
                     PNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAAL
                     ANMVQAAQNLRRG"
     gene            complement(29047..29862)
                     /locus_tag="RN951_001686"
     CDS             complement(29047..29862)
                     /locus_tag="RN951_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HDX2526699.1"
                     /translation="MATTQQSGFAPAASPLASTIVQTPDDAIVAGFTSIPSQGDNMPA
                     YHARPKQSDGPLPVVIVVQEIFGVHEHIRDICRRLALEGYLAIAPELYFREGDPNDFA
                     DIPTLLSGLVAKVPDSQVLADLDHVASWASRNGGDVHRLMITGFCWGGRITWLYAAHN
                     PQLKAAVAWYGKLTGDKSLNSPKQPVDIATDLNAPILGLYGGQDNSIPQESVETMRQA
                     LRAANAKAEIIVYPDAGHAFNADYRPSYHAASAEDGWQRMLEWFKQYGGKKSL"
     gene            30124..30885
                     /gene="udp"
                     /locus_tag="RN951_001687"
     CDS             30124..30885
                     /gene="udp"
                     /locus_tag="RN951_001687"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HDX2526700.1"
                     /translation="MSKSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKL
                     ASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHI
                     NVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSD
                     TFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAG
                     VIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL"
     gene            31026..32453
                     /gene="rmuC"
                     /locus_tag="RN951_001688"
     CDS             31026..32453
                     /gene="rmuC"
                     /locus_tag="RN951_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HDX2526701.1"
                     /translation="MDFSIMVYAVIALVGVAIGWLFASYQHAQQKAEQLAEREEMVAE
                     LSAAKQQITQSEHWRAECELLNNEVRSLQSINTSLEADLREVTTRMEAAQQHADDKIR
                     QMINSEQRLSEQFENLANRIFEHSNRRVDEQNRQSLNSLLSPLREQLDGFRRQVQDSF
                     GKEAQERHTLTHEIRNLQQLNAQMAQEAINLTRALKGDNKTQGNWGEVVLTRVLEASG
                     LREGYEYETQVSIENDARSRMQPDVIVRLPQGKDVVIDAKMTLVAYERYFNAEDDYTR
                     ESALQEHIASVRNHIRLLGRKDYQQLPGLRTLDYVLMFIPVEPAFLLALDRQPELITE
                     ALKNNIMLVSPTTLLVALRTIANLWRYEHQSRNAQQIADRASKLYDKMRLFIDDMSAI
                     GQSLDKAQDNYRQAMKKLSSGRGNVLAQAEAFRGLGVEIKREINPDLAEQAVSQDEEY
                     RLRSVPEQPNDEAYQRDDEYNQQSR"
     gene            32548..33303
                     /gene="ubiE"
                     /locus_tag="RN951_001689"
     CDS             32548..33303
                     /gene="ubiE"
                     /locus_tag="RN951_001689"
                     /EC_number="2.1.1.163"
                     /EC_number="2.1.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional demethylmenaquinone
                     methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol
                     methylase UbiE"
                     /protein_id="HDX2526702.1"
                     /translation="MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMS
                     FGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESMLK
                     MGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKDKALRSMYRVL
                     KPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVANDADSYRYLAESIRMHPDQ
                     DTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF"
     gene            33317..33922
                     /gene="ubiJ"
                     /locus_tag="RN951_001690"
     CDS             33317..33922
                     /gene="ubiJ"
                     /locus_tag="RN951_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis protein UbiJ"
                     /protein_id="HDX2526703.1"
                     /translation="MPFKPLVTAGIESLLNTFLYRSPALKTARSRLLGKVLRVEVKGF
                     STSLILVFSERQVDVLGEWAGDADCTVIAYASVLPKLRDRQQLTALIRSGELEVQGDI
                     QVVQNFVALADLAEFDPAELLAPYTGDIAAEGISKAMRGGAKFLHHGIKRQQRYVAEA
                     ITEEWRMAPGPLEVAWFAEETAAVERAVDALTKRLEKLEAK"
     gene            33919..35559
                     /gene="ubiB"
                     /locus_tag="RN951_001691"
     CDS             33919..35559
                     /gene="ubiB"
                     /locus_tag="RN951_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis regulatory protein
                     kinase UbiB"
                     /protein_id="HDX2526704.1"
                     /translation="MTPGEVRRLYFIIRTFLSYGLDELIPKMRITLPLRLWRYSLFWM
                     PNRHKDKLLGERLRLALQELGPVWIKFGQMLSTRRDLFPPHIADQLALLQDKVAPFDG
                     KLAKQQIEAAMGGLPVEAWFDDFEIKPLASASIAQVHTARLKSNGKEVVIKVIRPDIL
                     PVIKADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRR
                     NFEDSPMLYIPEVYPDYCSEGMMVMERIYGIPVSDVAALEKNGTNMKLLAERGVQVFF
                     TQVFRDSFFHADMHPGNIFVSYEHPENPKYIGIDCGIVGSLNKEDKRYLAENFIAFFN
                     RDYRKVAELHVDSGWVPPDTNVEEFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTAR
                     RFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALVRAF
                     KEKAPFWVEKMPELPELVYDSLRQGKYLQHSVDKIARELQSNHVRQGQSRYFLGIGAT
                     LVLSGTFLLVSRPEWGLMPGWLMAGGLIAWFVGWRKTR"
     gene            35638..35907
                     /gene="tatA"
                     /locus_tag="RN951_001692"
     CDS             35638..35907
                     /gene="tatA"
                     /locus_tag="RN951_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatA"
                     /protein_id="HDX2526705.1"
                     /translation="MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMS
                     DDEPKQDKTSQDADFTAKTIADKQADTNQEQAKTEDAKRHDKEQV"
     gene            35911..36426
                     /gene="tatB"
                     /locus_tag="RN951_001693"
     CDS             35911..36426
                     /gene="tatB"
                     /locus_tag="RN951_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatB"
                     /protein_id="HDX2526706.1"
                     /translation="MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLAT
                     TVQNELTQELKLQEFQDSLKKVEKASLTNLTPELKASMDELRQAAESMKRSYVANDPE
                     KASDEAHTIHNPVVKDNEAAHEGVTPAAAQTQASSPEQKPETTPEPVVKPAADAEPKT
                     AAPSPSSSDKP"
     gene            36429..37205
                     /gene="tatC"
                     /locus_tag="RN951_001694"
     CDS             36429..37205
                     /gene="tatC"
                     /locus_tag="RN951_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatC"
                     /protein_id="HDX2526707.1"
                     /translation="MSVEDTQPLITHLIELRKRLLNCIIAVIVIFLCLVYFANDIYHL
                     VSAPLIKQLPQGSTMIATDVASPFFTPIKLTFMVSLILSAPVILYQVWAFIAPALYKH
                     ERRLVVPLLVSSSLLFYIGMAFAYFVVFPLAFGFLANTAPEGVQVSTDIASYLSFVMA
                     LFMAFGVSFEVPVAIVLLCWMGITSPEDLRKKRPYVLVGAFVVGMLLTPPDVFSQTLL
                     AIPMYCLFEIGVFFSRFYVGKGRNREEENDAEAESEKTEE"
     gene            37247..38029
                     /gene="tatD"
                     /locus_tag="RN951_001695"
     CDS             37247..38029
                     /gene="tatD"
                     /locus_tag="RN951_001695"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' ssDNA/RNA exonuclease TatD"
                     /protein_id="HDX2526708.1"
                     /translation="MFDIGVNLTSSQFAKDRDDVVACAFDAGVNGLLITGTNLRESQQ
                     AQKLARQYSSCWSTAGVHPHDSSQWQAATEEAIIELAAQPEVVAIGECGLDFNRNFST
                     PEEQERAFVAQLRIAADLNMPVFMHCRDAHERFMTLLEPWLDKLPGAVLHCFTGTREE
                     MQACVAHGIYIGITGWVCDERRGLELRELLPLIPAEKLLIETDAPYLLPRDLTPKPSS
                     RRNEPAHLPHILQRIAHWRGEDAAWLAATTDANVKTLFGIAF"
     gene            complement(38026..38514)
                     /gene="rfaH"
                     /locus_tag="RN951_001696"
     CDS             complement(38026..38514)
                     /gene="rfaH"
                     /locus_tag="RN951_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription/translation regulatory transformer
                     protein RfaH"
                     /protein_id="HDX2526709.1"
                     /translation="MQSWYLLYCKRGQLQRAQEHLERQAVNCLAPMITLEKIVRGKRT
                     AVSEPLFPNYLFVEFDPEVIHTTTINATRGVSHFVRFGASPAIVPSAVIHQLSVYKPK
                     DIVDPATPYPGDKVIITEGAFEGFQAIFTEPDGEARSMLLLNLINKEIKHSVKNTEFR
                     KL"
     gene            38681..40174
                     /gene="ubiD"
                     /locus_tag="RN951_001697"
     CDS             38681..40174
                     /gene="ubiD"
                     /locus_tag="RN951_001697"
                     /EC_number="4.1.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-polyprenylbenzoate decarboxylase"
                     /protein_id="HDX2526710.1"
                     /translation="MDAMKYNDLRDFLTLLEQQGELKRITLPVDPHLEITEIADRTLR
                     AGGPALLFENPKGYSMPVLCNLFGTPKRVAMGMGQEDVSALREVGKLLAFLKEPEPPK
                     GFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIVSGDDVDLNRIPIMTCWPEDAAPLIT
                     WGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEWCAAHPGERFPVS
                     VALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCISNDLEVPASAEIVLEGY
                     IEQGETAPEGPYGDHTGYYNEVDSFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGV
                     ALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQF
                     MYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSK
                     MGLDATNKWPGETQREWGRPIKKDPDVVAHIDAIWDELAIFNNGKSA"
     gene            40220..40921
                     /gene="fre"
                     /locus_tag="RN951_001698"
     CDS             40220..40921
                     /gene="fre"
                     /locus_tag="RN951_001698"
                     /EC_number="1.5.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-flavin reductase"
                     /protein_id="HDX2526711.1"
                     /translation="MTTLSCKVTSVEAITDTVYRVRIVPDAAFSFRAGQYLMVVMDER
                     DKRPFSMASTPDEKGFIELHIGASEINLYAKAVMDRILKDHQIVVDIPHGEAWLRDDE
                     ERPMILIAGGTGFSYARSILLTALARNPNRDITIYWGGREEQHLYDLCELEALSLKHP
                     GLQVVPVVEQPEAGWRGRTGTVLTAVLQDHGTLAEHDIYIAGRFEMAKIARDLFCSER
                     NAREDRLFGDAFAFI"
     gene            complement(41204..42367)
                     /gene="fadA"
                     /locus_tag="RN951_001699"
     CDS             complement(41204..42367)
                     /gene="fadA"
                     /locus_tag="RN951_001699"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadA"
                     /protein_id="HDX2526712.1"
                     /translation="MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPA
                     LEAAALDDIYWGCVQQTLEQGFNIARNAALLAEVPHSVPAVTVNRLCGSSMQALHDAA
                     RMIMTGDAQACLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLARMHGI
                     SREMQDAFAARSHARAWAATQSAAFKNEIIPTGGHDADGVLKQFNYDEVIRPETTVEA
                     LATLRPAFDPVNGMVTAGTSSALSDGAAAMLVMSESRAHELGLKPRARVRSMAVVGCD
                     PSIMGYGPVPASKLALKKAGLSASDIGVFEMNEAFAAQILPCIKDLGLIEQIDEKINL
                     NGGAIALGHPLGCSGARISTTLLNLMERKDVQFGLATMCIGLGQGIATVFERV"
     gene            complement(42377..44566)
                     /gene="fadB"
                     /locus_tag="RN951_001700"
     CDS             complement(42377..44566)
                     /gene="fadB"
                     /locus_tag="RN951_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadB"
                     /protein_id="HDX2526713.1"
                     /translation="MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGEAIG
                     VLEQQSDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLP
                     VPTIAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGA
                     DSALEIIAAGKDVGADQALKIGLVDGVVKAEKLVEGAKAVLRQAINGDLDWKAKRQPK
                     LEPLKLSKIEATMSFTIAKGMVAQTAGKHYPAPITAVKTIEAAARFGREEALNLENKS
                     FVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDVETPKQAAVLGAGIMGGGIAYQSAW
                     KGVPVVMKDINDKSLTLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDR
                     VDIVVEAVVENPKVKKAVLAETEQKVRQDTVLASNTSTIPISELANALERPENFCGMH
                     FFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFA
                     GFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQK
                     DYRDAIDALFDANRFGQKNGLGFWRYKEDSKGKPKKEEDAAVEDLLAEVSQPKRDFSE
                     EEIIARMMIPMVNEVVRCLEEGIIATPAEADMALVYGLGFPPFHGGAFRWLDTLGSAK
                     YLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPARPVGDLKTA"
     gene            44756..46087
                     /gene="pepQ"
                     /locus_tag="RN951_001701"
     CDS             44756..46087
                     /gene="pepQ"
                     /locus_tag="RN951_001701"
                     /EC_number="3.4.13.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidase"
                     /protein_id="HDX2526714.1"
                     /translation="MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLD
                     DHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTE
                     DVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRS
                     FKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIV
                     ALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKD
                     VNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMP
                     HGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIES
                     LLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA"
     gene            46087..46701
                     /locus_tag="RN951_001702"
     CDS             46087..46701
                     /locus_tag="RN951_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418290.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMPACT family protein"
                     /protein_id="HDX2526715.1"
                     /translation="MESWLIPAAPVTVVEEIKKSRFITMLAHTDGVEAAKAFVESVRA
                     EHPDARHHCVAWVAGAPDDSQQLGFSDDGEPAGTAGKPMLAQLMGSGVGEITAVVVRY
                     YGGILLGTGGLVKAYGGGVNQALRQLTTQRKTPLTEYTLQCEYHQLTGIEALLGQCDG
                     KIINSDYQAFVLLRVALPAAKVAEFSAKLADFSRGSLQLLAIEE"
     gene            46740..48191
                     /gene="trkH"
                     /locus_tag="RN951_001703"
     CDS             46740..48191
                     /gene="trkH"
                     /locus_tag="RN951_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkH"
                     /protein_id="HDX2526716.1"
                     /translation="MHFRAITRIVGLLVILFSGTMIIPGLVALIYRDGAGRAFTQTFF
                     VALAIGSMLWWPNRKEKGELKSREGFLIVVLFWTVLGSVGALPFIFSESPNLTITDAF
                     FESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQL
                     YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTVACALALWFAGMDAFDAIGHSFATI
                     AIGGFSTHDASIGYFDSPTINTIIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRM
                     FIGVQFTLVVICTLVLWFHNVYSSALMTINQAFFQVVSMATTAGFTTDSIARWPLFLP
                     VLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKRLVHPNAVYSIKLGNRALPER
                     ILEAVWGFFSAYALVFIVSMLAIIATGVDDFSAFASVVATLNNLGPGLGVVADNFTSM
                     NPVAKWILIANMLFGRLEVFTLLVLFTPTFWRE"
     gene            48203..48748
                     /gene="hemG"
                     /locus_tag="RN951_001704"
     CDS             48203..48748
                     /gene="hemG"
                     /locus_tag="RN951_001704"
                     /EC_number="1.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="menaquinone-dependent protoporphyrinogen IX
                     dehydrogenase"
                     /protein_id="HDX2526717.1"
                     /translation="MKTLILFSTRDGQTREIASYLASELKELGIQADVANVHRIEEPQ
                     WENYDRVVIGASIRYGHYHSAFQEFVKKHATRLNSMPSAFYSVNLVARKPEKRTPQTN
                     SYARKFLMNSQWRPDRCAVIAGALRYPRYRWYDRFMIKLIMKMSGGETDTRKEVVYTD
                     WEQVANFAREIAHLTDKPTLK"
BASE COUNT        11353 a        12555 c        13282 g        11781 t
ORIGIN      
        1 atcaagctca ggttaaatat tcactcagga agttattact caggaagcaa agaggattac
       61 agaattatct cataacaagt gttaagggat gttatttccc gattctctgt ggcataataa
      121 acgagtagat gctcattcca tctcttatgt tcgccttagt gcctcataaa ctccggaatg
      181 acgcagagcc gtttacggtg cttatcgtcc actgacagat gtcgcttatg cctcatcaga
      241 caccatggac acaacgttga gtgaagcacc cacttgttgt catacagacc tgttttaacg
      301 cctgctccgt aataagagca ggcgtttttt tatgtatcag gaaggccccg gaggtgcttg
      361 cctccgggtg agaaggaact actgtggcgg gttattctgc aacgttaaca tcaaaccgtc
      421 gcgacgcatc gctgcagctt cttccggctt gtgcagtctg tccagcgcgt cggcaagcca
      481 tgcgtaatcg taggcgtccg gacgttgttt cagcgctgcg cggaaggcga gcgatgcttc
      541 ctgccattct ccgtgcttca tcagtgactg gcccagtgtg ctccacaaca gcgggcgatc
      601 gccgacgttt ttgatttgct ggcgcagcac tttttccagc tgttccggat tgtttgtttt
      661 cagtcgagga atcggcagca gtaggcgatc gtcgtactgg cgtttcaggc catcgatgat
      721 aatttgctgg gcagtatcat gatcgtcaca ttcaataaga tgttccgcca ttgccacctg
      781 caacgctacc tgatgacgcg ttttccggct ttggtttttc caccagttac gcaaaccttc
      841 gctaccgtta tcggcacgcg cctgatccat caggccaatc catgcctgtt gttccagcat
      901 tgcacgatgt tcttcatcac caacatgggc tttcgccatt gatgggataa tatccagcag
      961 cgaactccat gcacctgtgc ggatatacgc ctgttccgcc agacgtaata cttccggatg
     1021 gcgtggcgta acttccagca gcttatccac gccgtggcgt gcagcatggt tttcattacg
     1081 ggccagttgc agacgtacgc gggtgatttc taccggaatg gtgtcgttgc cggccagctc
     1141 cgctgcgcgt tccagatgtt ggttggcgcg tgcttcatca ccacgttgtt gcgcggcttc
     1201 ggcagccagt agatagttca ccaccggttg ttccgcgtga tcggcatttt tcgccatcag
     1261 cttttcaact tgctgataat cgccttccgc cagtttcagc agcgcctgtt cggtctgctt
     1321 acgtgcacgg cgacgcttac gtccgacaaa ccacccacgg gtgtgcgcgc cagtgcggaa
     1381 gatccgccgc agtagccact caatggcaaa cagcactacc atcgccagaa tcaatatgat
     1441 cgccaggccc gtgacgctgg tttcgatatt gtagttgtcg gtctggatca gcacataacc
     1501 ctgatggccg gcaatcatcg ggccaaccac gatccccgca atcagcaaca caaagagcaa
     1561 taacactttt agcatggtta ttctccttgc ggcgcggctg ccggagtatc agcttgcggt
     1621 gcaggtgcag gtttagcttc cgttgtcccc gctgccggtt gtgccagcag gttacgcacg
     1681 cgagtctgca tcagtttttc cagcatcgcc tggctttgca gggtttccgg aagatccatc
     1741 gagatatttt gctggcttaa ctggtccacc tcgtcgagga acgctttggt ggtggcatca
     1801 tcagtatcgt agtaagcacg tacccaggtg gagacgttct ccagcgcctg gcgataagtc
     1861 tcttcctggt gacgcggtac agcttgtgct gcgaccagca ggcgagagcg aatattttcg
     1921 cgcagataga tatcctgatt tggcgctaac agcggtacgg cggtgtcatc acgacggcga
     1981 atcgtaatga agttgtccat aaagttctgc cagctttttt gcagattgat acgccattcg
     2041 ctgatggaac tggaaagctc ttcaccgtct gaatccatcg gcgaaccatc gctgtcatta
     2101 tcggctagac gcaggttatc tacctgattt gaaagctgat taagcttaag gatgatgccg
     2161 tcataatcca cctgcgatac tgcagaaagg ctggcgatat catcggtaat tgcccgacga
     2221 acggtaatca gactcgggtc attcatatcc gccaggctgg cgtctgcact tttcagcaac
     2281 gctgcagcgg tcgtgacgtc ctgatcgctc cacagcttcc gtccggcgag tttcaccaga
     2341 aaatcggcct gagccagcag ccaggtttta gcatcgctgc cggaaatggt ggcgaccttt
     2401 tgttggactt catccaactg ttttgccagc gtttcttgct gacgattcgc ctgcttaagt
     2461 tgtgcagctt gttgcttaat aatgccttcc agctcggctt tttggctctc ctgggctttt
     2521 tgcaatgccg tcagttggtt agccagggca tcgctggtgg cggtctgatt gacggcctgt
     2581 tgtttacccc agccatacaa accgatgccc gccgccagag caatagcgat agccaccgcg
     2641 ctgagaatca atgcggtatt gttcttactc tttttttctg ttgcgacagg ttgtgacgtg
     2701 gtgtccacgg cctccctggt ctcttcaacc acggcggagg ttttttcttg ttccgtcatt
     2761 atggcttcct gttatgagag ttattgtaat gcccgtaaaa gcgcatcgtt gtcagcgtta
     2821 tcggcgacct taatgtcttg ccagcccagt tcccgggcga gtttcgccaa acgctcactg
     2881 acgaccaata gtcgacagtg tagtaaccag tgctcacgat accattgtgg gatcagcgac
     2941 cagagttgct gcaacatttc accgctggta acaacgacca tcgtcacctc gcgggcttgc
     3001 cagcgcatcg cttcttctgc accatcgtaa tggattgcgc atcgttgata acattcacaa
     3061 aaagtgacct cagcaccgcg cgccgtcagg gtatccccaa ttagctcacg accaccattg
     3121 ccacgtaata tcagcgcacg tttgcccgca atattttgta attcaggtaa ttgtagcaag
     3181 acttcgctga tttcccgatc ctgcgggtag agaatcttct gtccgcttac ggtatgtagt
     3241 gccagtgcgg tggtgcgtcc aatggcgaaa taatcaggta gtcggggcca tttacgatct
     3301 tgctgatgca gctgtgattg ggcaaaagca accgcgtgtt gcgagagggc aaacaacaga
     3361 tcgctctccc ccagcgctgc cagttgatca gcaagttgcg gtaattgttg acccggagaa
     3421 aactcaatca gcggaaaatg ccaggccacc tgccccagtg tgcgcagacg gctcactaac
     3481 tcttctccag cgggagacgg gcgggtgaca aggatactca tgccggggcg tctccgttat
     3541 agacttcagc gaggatctcg cgcgcgccgt tattcagtag ctcttctgcc agcgaaatcc
     3601 ccatttgttc ggcatcttgc ggcgcaccgc ggcgttcacc gcgaataatc tgcgaaccgt
     3661 ccggcgcgcc gaccagcgca cgcagccaga tttcgccatc aataagctcg gcgtagctac
     3721 caattggcac ctgacatccg ccttcgagac gggtattcat ggcgcgttct gcggtaacgc
     3781 gcagtgcagt ttcgtggtga ttcagcgcgg caagcagctc gcgagtgcgt gaatcatcaa
     3841 ggcggcattc aatacccacc gcaccttgtc ctaccgccgg aagagaaatc tcgggtggca
     3901 acgcggcgcg aatacgtgac tccagaccta aacgttttag tccggctacg gcaagaatga
     3961 tggcatcgta ttcgccgtta tccagtttgc tcaggcgagt gccgacgttg ccgcgcaggg
     4021 agcggataat cagatccgga cggcgttcag ccagttggca ctggcgacgt aaactggacg
     4081 tcccgacgat actgcctgcc ggtaacgcat ccagactgtc atagttattg gacacaaagg
     4141 catcgcgagg atcttcacgc tcacaaatag tgaccagtcc cagaccttgc gggaattcaa
     4201 ccggcacatc tttcattgag tgtacggcga tatcggcgcg attttcgagg agcgcgactt
     4261 ccagctcttt tacaaataag ccttttccgc ctactttcgc cagcggcgta tcaagaatca
     4321 catcgccgcg cgtcaccatc ggtaccagtt caacgaccag gcccggatgg ctcgccatca
     4381 acttgtcttt gacatagtgt gcctgccaga gtgcaagtgg gctttggcgt gtggcaattc
     4441 ttaaaacatt gtctaacatg cttgttaccg tcattatcat ccgtggtcca tcctaacatc
     4501 cttgccagag tgatgtcagt gttgtggtga aacgtagacg cctgcgcaaa ccgtaaaatg
     4561 aggtctggca gtggatcctg acaggcgttt cacgccgttg taataaggaa tttacagaga
     4621 ataaacggtg ctacacttgt atgtagcgca tctttcttta cggtcaatca gcaaggtgtt
     4681 aaattgatca cgttttagac cattttttcg tcgtgaaact aaaaaaacca ggcgcgaaaa
     4741 gtggtaacgg ttacctttga catacgaaat atcccgaatg ccgcgtgtta ccgttgatgt
     4801 tggcggaatc acagtcatga cgggtagcaa atcaggcgat acgtcttgta cctctatatt
     4861 gagactctga aacagagact ggatgccata aatcaattgc gtgtggatcg cgcgcttgct
     4921 gctatggggc ctgcattcca acaggtctac agtctactgc cgacattgtt gcactatcac
     4981 catccgctaa tgccgggtta ccttgatggt aacgttccca aaggcatttg cctttacacg
     5041 cctgatgaaa ctcaacgcca ctacctgaac gagcttgaac tgtatcgtgg aatgtcagta
     5101 caggatccgc cgaaaggtga gcttccaatt actggtgtat acaccatggg cagcacctcg
     5161 tccgtagggc aaagttgttc ctctgacctg gatatctggg tctgtcatca atcctggctc
     5221 gatagcgaag agcgccaatt gctacaacgt aaatgtagcc tgctggaaaa ctgggccgcc
     5281 tcgctgggtg tggaagtcag cttcttcctg attgatgaaa accgcttccg tcataatgaa
     5341 agcggcagcc tggggggcga agattgtggc tccacccagc atatactgct gcttgacgaa
     5401 ttttatcgta ccgccgtgcg tctcgccggt aagcgtattc tgtggaatat ggtgccgtgc
     5461 gacgaagaag agcattacga cgactatgtg atgacgcttt acgcgcaggg cgtgctgacg
     5521 ccaaatgaat ggctggatct cggtggctta agctcgcttt ctgctgaaga gtactttggt
     5581 gccagccttt ggcagctcta caagagtatc gattccccat acaaagcggt actgaaaaca
     5641 ctgctgctgg aagcctattc ctgggaatac ccgaacccac gtctgctggc gaaagatatc
     5701 aaacagcgtt tgcacgacgg cgagattgta tcgtttggtc tcgatccata ctgcatgatg
     5761 ctggagcgtg ttactgaata cctgacggcg attgaagatt ttacccgtct ggatttagta
     5821 cgtcgctgct tctatttaaa agtgtgcgaa aagctcagcc gtgaacgcgc ctgcgtaggc
     5881 tggcgtcgcg cagtgttgag ccagttagtg agcgagtggg gttgggacga agctcgtctg
     5941 gcaatgctcg ataaccgcgc taactggaag attgatcagg tgcgtgaggc gcacaacgag
     6001 ttgctcgacg cgatgatgca gagctaccgt aatctgatcc gctttgcgcg tcgcaataac
     6061 cttagcgtct ccgccagtcc gcaggatatc ggcgtgctga cgcgtaagct gtatgccgcg
     6121 tttgaagcat taccaggtaa agtgacgctg gtaaacccgc agatttcacc cgatctctcg
     6181 gaaccgaatc tgacctttat ttatgtgccg ccgggccggg ctaaccgttc aggttggtat
     6241 ctgtataacc gcgcgccaaa tattgagtcg atcatcagcc atcagccgct ggaatataac
     6301 cgttacctga ataaactggt ggcgtgggca tggtttaacg gcctgctgac ctcgcgcacc
     6361 cgtttgtata ttaaaggtaa cggcattgtc gatttgccta agttgcagga gatggtcgcc
     6421 gacgtgtcgc accatttccc gctgcgctta cctgcaccga caccgaaggc gctctacagc
     6481 ccgtgtgaga tccgccatct ggcgattatc gttaacctgg aatatgaccc gacagcggcg
     6541 ttccgcaatc aggtggtgca tttcgatttc cgtaagctgg atgtcttcag ctttggcgag
     6601 aatcaaaatt gcctggtagg tagcgttgac ctgctgtacc gcaactcgtg gaacgaagtg
     6661 cgtacgctgc acttcaacgg cgagcaatcg atgatcgaag ccctgaaaac tattctcggc
     6721 aaaatgcatc aggacgccgc accgccagat agcgtggaag tcttctgtta tagccagcat
     6781 ctgcgcggct taattcgtac tcgcgtgcag caactggttt ctgagtgtat tgaattgcgt
     6841 ctttccagca cccgccagga aaccgggcgt ttcaaggcgc tgcgcgtttc tggtcaaacc
     6901 tgggggttgt tcttcgaacg cctgaatgta tcggtacaga aactggaaaa cgccatcgag
     6961 ttttatggcg cgatttcgca taacaaactg cacggcctgt cagtgcaggt tgaaaccaat
     7021 cacgtcaaat taccggcggt ggtggacggc tttgccagcg aagggatcat ccagttcttt
     7081 ttcgaagaaa cgcaagacga gaatggcttt aatatctaca ttctcgacga aagcaaccgg
     7141 gttgaggtat atcaccactg cgaaggcagc aaagaggagc tggtacgtga cgtcagtcgc
     7201 ttctactcgt catcgcatga ccgttttacc tacggctcaa gcttcatcaa cttcaacctg
     7261 ccgcagttct atcagattgt gaaggttgat ggtcgtgaac aggtgattcc gttccgcaca
     7321 aaatctatcg gtaacatgcc gcctgccaat caggatcacg atacgccgct attacagcaa
     7381 tatttttcgt gatgaacgtg ccggaaagcg aggcttatcc ggcatgcaat cttagcggaa
     7441 actgactgtt tcacccgcct gctgcgtcgc cgcctgttcc agcaaatccc agaaggtttc
     7501 gccgctgcga tcacaaatcc actcatcgcc tttcaggtca aaatggtagc cgccctgttt
     7561 ggttgccagc catacctggt gcagcggctc ctggcggttg ataatgattt tgctgccatt
     7621 ctcaaaggta atggtcagta cgccgccgtt gatttcgcag tcgatatcgc tgtcgccatc
     7681 ccagtcgtcc aggcgttctt caatggtcag ccagagttga tcagccaggc gatgaaattc
     7741 actgtcgttc attgttgtat cctgttttta agtgatggcg gcagtatagc ggcatggggt
     7801 cagggcttca aagtttgcac ctctgcggct gcgttccggc acgattcatc cgtcaccgga
     7861 ataatgatgt ctctgtgtag cgaaagattt gtctcttcat tagggcgcag ttacaccacg
     7921 tctttccctg tttctggtaa acattatgat caggtttacc gagcgagcat cctcacgctg
     7981 acggaactaa aaaagacaac aaacaaacca cattgcgata gtgcataaag ccatcctggc
     8041 gcgaggtgcc gatcacgaaa ctaccagcaa aacataaatc cccacgagta agcgttatac
     8101 tcgcagcatt tcctcacttt tcagacttca taaagagtcg ctaaacgctt gcttttacgt
     8161 cttctcctgc gatgatagaa agcagaaagc gatgaacttt acaggcaatc cataatgaaa
     8221 aacgtgttta aggcactcac tgtattactt actctcttca gcctgacggg ctgcggtctg
     8281 aaaggtccgc tctatttccc gcctgcagat aaaaacgcac cgccgccgac caaaccggta
     8341 gagacgcaaa cgcaatccac ggtgccggat aaaaacgatc gcgccactgg cgatggtcca
     8401 tcccaggtga attactaaaa gtcagtttct gtacccgcgt gattggagta aatgatgcag
     8461 ttctcgaaaa tgcatggcct tggcaacgat tttatggtcg tcgacgcggt aacgcagaat
     8521 gtcttttttt caccggagct gattcgtcgc ctggctgatc ggcacctggg ggtagggttt
     8581 gaccaactgc tggtggttga gccgccgtat gatcctgaac tggattttca ctatcgcatt
     8641 ttcaatgctg atggcagtga agtggcgcag tgcggcaacg gtgcgcgctg ctttgcccgt
     8701 tttgtgcgtc tgaaaggact gaccaataag cgtgatatcc gcgtcagcac cgccaacggg
     8761 cggatggttc tgaccgtcac cgatgatgat ctggtccgcg taaatatggg cgaacccaac
     8821 ttcgaacctt ccgccgtgcc gtttcgcgct aacaaagcgg aaaagaccta tattatgcgc
     8881 gccgccgagc agacaatctt atgcggcgtg gtgtcgatgg gaaatccgca ttgcgtgatt
     8941 caggtcgatg atgtcgatac cgcggcggta gaaacgcttg gtcctgttct ggaaagccac
     9001 gagcgttttc cggagcgcgc caatatcggt tttatgcaag tggttaagcg cgagcatatt
     9061 cgtttacgcg tttatgagcg tggggcagga gaaacccagg cctgcggcag cggcgcgtgt
     9121 gcggcggttg cagtagggat tcagcaaggt ttgctggccg aagaagtacg cgtggaactc
     9181 cccggcggtc gtcttgatat cgcctggaaa ggtccgggtc acccgttata tatgactggc
     9241 ccggcggtac atgtctacga cggatttatt catctatgaa gcaaccaggg gaagaactgc
     9301 aggaaacact cacggagctt gatgaccggg cggttgtcga ttatctgatt aaaaatcctg
     9361 agttttttat ccgtaatgcg cgcgcagtag aagcgatacg tgtgccgcat ccggtacgcg
     9421 gcaccgtttc gttggtcgag tggcacatgg cccgcgcacg taatcatatt catgttctgg
     9481 aagagaacat ggcgctgttg atggaacagg ctatcgccaa cgaaggcctg ttttatcgcc
     9541 tactctacct gcagcgcagt ctcaccgccg ccagcagtct cgacgatatg ctgatgcgct
     9601 ttcaccgctg ggcgcgcgat ctcggcctgg caggtgcgag tctgcgcctg tttccggatc
     9661 gctggcgctt aggtgcgccg tcgaaccaca ctcatctggc attaagccgt cagtctttcg
     9721 aaccgctgcg tattcagcgt ttggggcagg aacagcacta tcttgggccg cttaacggac
     9781 cagagctgct ggtggtgcta ccggaagcga aagcggtggg atcggtggcg atgtcgatgc
     9841 tgggaagcga tgctgatttg ggtgtcgtgc tgtttaccag tcgcgatgcc agtcactatc
     9901 aacaagggca aggaacgcag ttacttcatg aaattgcgct gatgttgccg gagcttctgg
     9961 agcgttggat tgaacgcgta tgaccgattt acacaccgat gtagaacgct acctacgtta
    10021 tctgagcgtg gagcgccagc ttagcccgat aaccctgctt aactaccagc gtcagcttga
    10081 ggcgatcatc aattttgcca gcgaaaacgg cctgcaaagc tggcagcaat gtgatgtgac
    10141 gatggtgcgc aattttgctg tacgcagtcg ccgtaaaggg ctgggagcag caagtctggc
    10201 gttacggctt tctgcgctac gtagcttttt tgactggctg gtcagccaga acgaactcaa
    10261 agctaacccg gcgaaaggtg tttcggcacc gaaagcgccg cgtcatctgc cgaaaaacat
    10321 cgacgtcgac gatatgaatc ggctgctgga tattgatatc aatgatcccc tcgctgtacg
    10381 cgaccgtgca atgctggaag tgatgtacgg cgcgggtctg cgtctttctg agctggtggg
    10441 gctggatatt aaacacctcg acctggagtc tggtgaagtg tgggttatgg ggaaaggcag
    10501 caaagagcgc cgcctgccga ttggtcgcaa cgctgtggcg tggattgagc actggcttga
    10561 tttgcgcgac ctgtttggta gcgaagacga cgcgcttttt ctgtcgaaac tgggcaagcg
    10621 tatctccgcg cgtaatgtgc agaaacgctt tgccgaatgg ggcataaaac aagggctgaa
    10681 taatcacgtt catccgcata aattacgtca ctcgttcgcc acgcatatgc tggagtcgag
    10741 cggcgatctt cgtggtgtgc aggagctgct gggtcatgcc aacctctcca ccacgcaaat
    10801 ctatactcat cttgattttc aacaccttgc ctcggtgtac gatgcggcgc atccacgcgc
    10861 caaacggggg aaataatgcg tttttaccgg cctttggggc gcatctcggc gctcaccttt
    10921 gacctggatg atacccttta cgataaccgt ccggtgattt tgcgcaccga gcgagaggcg
    10981 cttacctttg tgcaaaatta tcatccggcg ctgcgcagct tccagaatga agatctgcaa
    11041 cgcctgcgcc aggcggtacg ggaagcggaa cccgagattt atcacgacgt gacgcgctgg
    11101 cgttttcgtt cgattgaaca agcgatgctc gacgccgggc tgagtgccga agaagccagt
    11161 gcaggcgcac acgcagcaat gatcaacttt gccaaatggc gcagccgaat cgacgtcccg
    11221 cagcaaactc acgacacctt aaaacagctg gcgaagaaat ggccgctggt ggcgatcacc
    11281 aacggtaacg cccagccgga gctgtttggt ttgggggatt attttgagtt tgtgctgcgc
    11341 gctggcccgc acgggcgctc aaaaccgttc agcgatatgt actttttggc tgcggaaaaa
    11401 ctcaacgtgc cgatcggcga gatcttacat gttggggacg atctcaccac tgacgtgggt
    11461 ggggcaattc gcagcggaat gcaggcttgt tggatcagac cggaaaatgg cgatctgatg
    11521 caaacctggg acagccgttt actgccgcat ctggaaattt cccggttggc atctctgacc
    11581 tcgctgatat aatcagcaaa tctgtatata tacccagctt tttggcggag ggcgttgcgc
    11641 ttctccgccc aacctatttt tacgcggcgg tgccaatgga cgtttcttac ctgctcgaca
    11701 gccttaatga caaacagcgc gaagcggtgg ccgcgccacg cagcaacctt ctggtgctgg
    11761 cgggcgcggg cagtggtaag acgcgcgtac tggtgcatcg tatcgcctgg ttgatgagcg
    11821 tggaaaactg ctcgccatac tcgattatgg cggtgacgtt taccaacaaa gcggcggcgg
    11881 agatgcgtca tcgtatcggg caactgatgg gcacgagcca gggcggtatg tgggtcggca
    11941 ccttccacgg gctggcgcac cgtttgctgc gtgcgcacca tatggacgcc aatctgccgc
    12001 aggatttcca gatcctcgac agtgaagacc agctacgcct gcttaagcgt ctgatcaaag
    12061 ccatgaacct cgacgagaag cagtggccgc cgcggcaggc aatgtggtac atcaacagcc
    12121 agaaagatga aggcctgcgt ccgcatcata ttcaaagcta cggtaatccg gtggagcaga
    12181 cctggcagaa ggtgtatcag gcgtatcagg aagcgtgtga ccgcgcgggc ctggtggact
    12241 tcgccgagct gctgctgcgc gctcacgagt tgtggcttaa caagccgcat atcctgcaac
    12301 actaccgcga acgttttacc aatatcctgg tggacgaatt ccaggatacc aacaacattc
    12361 agtacgcgtg gatccgcctg ctggcgggcg acaccggcaa agtgatgatc gtcggtgatg
    12421 acgaccagtc aatctacggc tggcgcgggg cgcaggtgga gaatattcag cgtttcctta
    12481 atgatttccc cggtgccgaa actattcgtc tggagcaaaa ctaccgctct accagcaata
    12541 ttctgagcgc cgctaacgcc ctgattgaaa acaataacgg gcgtctgggt aaaaaactgt
    12601 ggaccgatgg cgcggacggt gagcctattt ccctctattg cgcttttaac gaactcgatg
    12661 aagcgcgttt tgtggttaac cgcatcaaaa cctggcagga caacggcgga gcgcttgccg
    12721 agtgcgccat tctctaccgc agcaacgccc agtcgcgggt gctcgaagag gcgttattgc
    12781 aggccagtat gccgtaccgt atttacggcg ggatgcgctt cttcgaacgc caggaaatca
    12841 aagatgcgct ctcgtatctg cgcctgattg ccaaccgcaa cgacgacgcg gcctttgagc
    12901 gtgtggtgaa tacgccaacg cggggtattg gtgaccggac gctggacgtg gtacgtcaga
    12961 catcgcgcga tcgccagtta acactctggc aggcatgtcg tgagctgttg caggaaaaag
    13021 ccctcgccgg gcgagctgcc agcgccttgc agcgatttat ggaattaatc gacgccttag
    13081 cgcaggaaac tgccgatatg ccgctgcatg tacagactga ccgggtaatt aaagactccg
    13141 gcctgcgtac catgtatgag caggagaagg gcgaaaaagg tcagacgcgt atcgaaaact
    13201 tagaggaact ggtgacggca acgcgccagt tcagctacaa cgaagaagac gaagatttaa
    13261 tgccgctgca ggcgttcctc tcccatgcgg cactggaagc aggtgaaggg caggcggata
    13321 cctggcagga tgcggtgcag ttgatgacgc tacactcggc gaaaggcctg gagttcccgc
    13381 aggtgtttat cgttggtatg gaagagggca tgttcccaag ccagatgtcg ctggatgaag
    13441 gcgggcgtct ggaagaagaa cgccgtctgg cctacgttgg cgtaacccgc gcgatgcaga
    13501 aactgacgct gacctacgcg gaaacccgcc gtctgtatgg taaagaggtt taccatcgcc
    13561 cgtcgcgctt tatcggcgag ctgccggaag agtgtgtgga agaggtgcgc ctgcgcgcca
    13621 cggtaagccg cccggtcagc catcagcgga tgggtacgcc gatggtcgag aacgacagcg
    13681 gctacaagct cggccagcgc gtacgccacg ctaagtttgg tgaaggcacc attgtcaata
    13741 tggaaggcag cggtgagcat agccgtttgc aggtggcatt tcagggccag ggtattaaat
    13801 ggctggtggc ggcatacgcc cggctggagt cggtgtaacg ttgccggatg cggtgctgcg
    13861 caccttattt ggcctaaaaa atcattcaga ttcaataaat tgcaacgtca tgtaggccgg
    13921 atagggcgtt tacgccgcat ccggcatctg cgccatcttc agtatctgac acaaaactat
    13981 cgttttaacc tttccgctcg acggaaatca tggtgacaaa aggatagcgt tgccacggga
    14041 ttgccccgcc tttcatatac atatgtgaaa tcgtgccatc aagataaagc agctgctcaa
    14101 cgttcagttt cgctttggca taacaggcaa aatcataaaa atttgttgcc tgctggctca
    14161 acaaaaacac ggcgttccca tgtttattaa tcccaacacc gttacgaatt ttgcttgagg
    14221 cgacgttggg atgaatacgc ggattaatta caccgttttc catcaacatt ggccctgact
    14281 gcaccgcaaa ctgaatctct ttactggttt tgaaggcatc cagacgaacg atgccgactt
    14341 tatctcccgc gacataaaac acgccgccag gacggataaa gaaattccct tcacctgaag
    14401 cgagatttaa cgccaccttc tgctgaccgt tttcgatgta caaaccgagc ggcgcatagc
    14461 tttcatcata gatgccgccg ttcatcgcca tctgcacctg accctgacta ttaatatccg
    14521 ccagcagagc atgtaacgtt ccccacgctt cgccattggc tttttgccag tacattttca
    14581 cccgctctgt ttgaggatta acggtatacg cctgtacggt cagcgtcgga tctgagagtg
    14641 cgcaatcatc agcggcaaca gcaaacaagg gaagtaaggt gagggcgaga aaaatccgtt
    14701 tgagattcaa ggtgatcatt cctttaccaa tgagtagctg atgcgccatt ataggtcctg
    14761 gatgtgggat ttttttatcc tgttagcgac cttgacgagt accaaaaagc gcgaagttca
    14821 actattgttc tgtggtgttc tgttgcgtgt tgacggcaaa attttgctgg cgtaacatgc
    14881 gcgcacgatc actctaagag gacattcgcc ttggacacac ccagtagata ctggctcact
    14941 atcctgtcat ccaggatcaa ctcctaaggc tatccctttt tgctgatagc cttagcggtt
    15001 gtcagcgacc tcaatttttc ccgtcgcgct gagtcaggct gtttaatggt ctgaaaccca
    15061 atttgtttct gtgtgcccac cgaactgtcc gatattttaa gcattgggag tcccggtcat
    15121 gctgagcgca tttcaactgg aaaataaccg actgacccgg ctggaagtcg aagagtcaca
    15181 accccttgta aatgcagtat ggattgatct tgtcgaaccg gacgacgacg agcgactgcg
    15241 cgtacaatct gaacttggcc agagcctggc aacccgcccg gaactggaag acatcgaagc
    15301 atcggcacgt ttctttgaag acgacgacgg cctgcatatt cactccttct tcttctttga
    15361 agatgcggaa gatcacgccg gtaactccac tgtggcattt accatccgtg atggtcgtct
    15421 gtttactctg cgtgagcgtg aactgcccgc ttttcgtctg tatcgtatgc gtgcccgtag
    15481 ccagtcgatg gtagacggta acgcctacga gttgctgctg gatctgttcg aaaccaaaat
    15541 cgaacagttg gcagatgaaa ttgaaaatat ctatagcgac ctggagcagt tgagccgggt
    15601 gattatggaa gggcatcagg gcgatgagta cgacgaggcg ctctccactc tggcggaact
    15661 ggaagatatc ggctggaaag ttcgcctgtg tctgatggat acccagcgcg cgctcaactt
    15721 cctggtgcgt aaagcgcgtt taccgggtgg gcaactggag caggcgcgtg aaatcctgcg
    15781 agatatcgaa tccctgctgc cgcataacga atccctgttc cagaaggtga acttcctgat
    15841 gcaggcggca atgggtttta tcaacatcga gcagaaccgc atcatcaaaa tcttctcggt
    15901 ggtatccgtg gtattcctgc cgccgacgct cgttgcttcc agctatggca tgaactttga
    15961 gtttatgcca gaactgaagt ggagcttcgg ctaccctgcc gcgattatct ttatgatcct
    16021 cgcgggcctg gcaccgtatc tgtactttaa gcggaagaac tggttgtaaa aaacgagagc
    16081 ggtggcttag tctggctaag ccacctgtta ttcaaaggct ccaggtattt aaccctttta
    16141 cctctttctc atagaaccat ttgttcgtgt taacagcaac ataggctgct acggcaattc
    16201 ccagaatgtt aacgccaatt agtgcaccaa caaatagaga tagaatacca agtaatagaa
    16261 ctataattgc ttttttccat aaccccagga caaataaata tatccaggaa cagaagaaag
    16321 caatgaaatt catttgaata gttaagcgtt gtcttacttt taatgcttta aatgctgctt
    16381 tatattctgg tgttgccccc cagaatccag gaaaaccatg ttgatcataa aaattaaatc
    16441 ggtatttcca tttttcactt aatgaaccat cgttcatata ttccttactc ataaatactc
    16501 cataactatt gttttgatga atcagtaggt gcaagcatta gcatactgaa agtggaaaaa
    16561 taacaaatca aaaaaatcat cgaaccattg cctgaacagg caaaatcttc ggctatcatt
    16621 gtgatgatag agatgatata tactgctaat gtaccaaaaa cataagtttt tatatagatg
    16681 aaaccactat cacggagtcg ctggcaattc atgttgatga cgagataatg gagtacgatg
    16741 gtagagacta taacaagaaa gcctgcttct ccatcgttaa aaaagataat aagaaaggca
    16801 aaaatgaaat ttattaaaat aaatgaaaat atataacgac gtctggaaat cttaccgtta
    16861 gatgttggga taaatatgcg taacataaat tttacatcct tgtatgagtc tccggtcagc
    16921 atggcaatat gcccactctc atgcaagagt cggcatattt tttcagaata tatttatttt
    16981 ttatttggac gttctacgct gcgtataaat cgcatccatc acaaaaattg ccagcgccac
    17041 ccaaataaag gcgaaagtca ccatcttatc ggcacccggt ttttcaccat aaaacgtcac
    17101 agccagcagg aacatcagcg tcgggccaat gtactggaaa aagcctaacg ttgagagacg
    17161 caagcgcgtg gcagcggcgg taaaacacaa cagcggtacg gtagtgacaa taccggcggc
    17221 gatcagcagt aaattcagcg acatcgggtt ttgccccata tggctggttg agctgtcggc
    17281 aatagcaaac aggtaaattg ccgccacggg cagcagccac atggtttcga ttaacatgcc
    17341 ggtttgcgct tcaacggcaa tcttcttgcg taccagaccg tagaaggcaa aactaaatgc
    17401 cagtcccagc gcgataatag gtagcgaacc aaaagtccac agctggacta acacgccaca
    17461 tatcgccaga atcaccgcca gccattgcat ccggcggaat cgctcgccga ggaaaatcat
    17521 ccccagcaca atgttcacca gcgggttaat aaagtaacca aggctcgctt ccagcatatg
    17581 gtgattgttc accgcccaga taaacagtag ccagttgcca ccaatcagca cggcagagac
    17641 tgccagcata aaaattttct gtggcgtctg aatcagcgtt tttaaatagg accactggcg
    17701 gcaaatgctc atcagcacca ccataaagaa aaacgaccag atcacgcgat gcgtcaggat
    17761 ttcatcggcg ggcacgtagt aaatcaactt gaagtacgct ggcgctatac cccaaataaa
    17821 ataagcggca agagcgagta atacgccctg ccgcgtttgt tttgcatcca tcgggaatac
    17881 tcatttttaa ttggtaacag cagtttacct gcttttatgt cttcaaccta ccatataggt
    17941 ggcggtggca ctggcaatat aaagctgttc ttcattgtgt aattcaacgc gggcgacggc
    18001 gactttattg cctgcacgca acaggctact agtagcagta aaacgctcgc ccctgcctgg
    18061 gcgcagataa tcaacgcgaa gatcaatggt ccccatccgc gatagccgct ggcgtagttc
    18121 atcttcactg atggtttcgt ggcgggttaa ggtacttccc acgcacacca gaccggcggc
    18181 gacatccagc gccgacgcaa tgaccccgcc gtgcaaaatg ctttgcgccc agttgcccac
    18241 catcattggc tgatttttaa aggccagctg tgcgaactct ttttcgtaac gctccagttc
    18301 catccccaat gcgcggttaa atggcatgtg ataaacaaac atctcaccca ctaatttcag
    18361 ggcttgttca gcggtcagta cggcagacat atcatcctta cacttcattg gttaatgaaa
    18421 tgttgatttt atgcttcttt gttgttggtt tctactttag gaagggataa ctaacggcta
    18481 tggagttaag tatgtaaaat agcccgcaga aaaatattca ccttatcaat aattcgttac
    18541 ggagaacacg accgatgcgg actctgcagg gctggttgtt gccggtgttt atgttgccta
    18601 tggcagtata tgcacaagag gcaacggtga aagaggtgca tgacgcgcca gcggtgcgtg
    18661 gcagtattat cgccaatatg ctgcaggagc atgacaatcc gttcacgctc tatccttatg
    18721 acaccaacta cctcatttac acccaaacca gcgatctgaa taaagaagcg attgccagtt
    18781 acgactgggc ggaaaatgcg cgtaaggatg aagtaaagtt tcagttgagc ctggcatttc
    18841 cgctgtggcg tgggatttta ggcccgaact cggtgttggg tgcgtcttat acgcaaaaat
    18901 cctggtggca actgtccaat agcgaagagt cttcaccgtt tcgtgaaacc aactacgaac
    18961 cgcaattgtt cctcggtttt gccaccgatt accgttttgc aggttggacg ctgcgcgatg
    19021 tggagatggg gtataaccac gactctaacg ggcgttccga cccgacctcc cgcagctgga
    19081 accgccttta tactcgcctg atggcagaaa acggtaactg gctggtagaa gtgaagccgt
    19141 ggtatgtggt gggtaatact gacgataacc cggatatcac caaatatatg ggttactacc
    19201 agcttaaaat cggctatcac ctcggtgatg cggtgctcag tgcgaaagga cagtacaact
    19261 ggaacaccgg ctacggcggc gcggagttag gcttaagtta cccgatcacc aaacatgtgc
    19321 gcctttatac tcaggtttac agcggctatg gcgaatcgct catcgactat aacttcaacc
    19381 agacccgtgt cggtgtgggg gttatgctaa acgatttgtt ttgatgaacg gttgagtggt
    19441 tggcaaatct ggaatccagc atccaggatt accctctcag agactaaaag cattgcagtt
    19501 tctcgcgcag gcgctgaaaa tagcgcctgt ttttatttca ggcaatcggg gtgaatgtgg
    19561 cgcaggcgga agtgttgaat ctggagtccg gagctaaaca ggttttacaa gaaacctttg
    19621 gctaccaaca gtttcgcccc ggccaggaag aaattatcga cactgtgctt tccggccgcg
    19681 attgcctcgt cgtcatgccc actggtggcg gaaaatccct ttgctatcaa atccctgcct
    19741 tattgctaaa cggccttacc gtggttgttt caccgctgat ttcgttgatg aaagatcagg
    19801 tggatcaact gcaagccaac ggcgtggcgg cggcgtgcct taactcgacg caaacccgcg
    19861 aacagcaact tgaagtgatg acaggctgcc gcaccgggca aattcgtctg ctttatatcg
    19921 ccccggaacg cctgatgctg gataactttc ttgagcatct ggcgcactgg aatccggtgt
    19981 tattagccgt tgatgaagcg cactgtatct cccaatgggg ccacgatttc cgcccggaat
    20041 atgccgcgct cggtcagttg cgccagcggt tcccgacgct gccgtttatg gcgctgaccg
    20101 ccacagccga cgacaccacg cgccaggata tcgtgcgcct gctggggctg aacgatccgc
    20161 tgattcaaat cagcagtttt gaccgtccga atattcgcta catgctgatg gagaagttca
    20221 aaccgctcga tcagttgatg cgctacgtgc aggaacagcg cggtaagtca ggcattatct
    20281 actgcaacag ccgcgcgaaa gtagaagaca ccgctgcgcg cctgcaaagc aagggaatta
    20341 gcgcggcggc ctatcatgcc gggctggaaa ataatgttcg cgccgatgtg caggaaaaat
    20401 tccagcgcga tgacctgcaa attgtggtgg cgacggtggc gttcggcatg ggcatcaata
    20461 aaccaaacgt tcgcttcgtg gtccactttg atattccgcg caatatcgaa tcctattatc
    20521 aggaaaccgg acgcgccggg cgtgatggcc tgcccgcgga agcgatgctg ttttacgatc
    20581 cggctgatat ggcgtggctg cgccgttgtc tggaagagaa gccgcagggg cagttgcagg
    20641 atatcgagcg ccacaaactc aatgcgatgg gcgcgtttgc cgaagcgcaa acttgccgtc
    20701 gtctggtatt gctgaactat tttggcgaag ggcgtcagga gccgtgcggg aactgcgata
    20761 tctgcctcga tccgccgaaa cagtacgacg gttcaaccga tgctcagatt gccctttcca
    20821 ccattggtcg tgtgaatcag cggtttggga tgggttatgt ggtggaagtg attcgtggtg
    20881 ctaataacca gcgtatccgc gactatggtc atgacaaact gaaagtctat ggcatgggcc
    20941 gtgataaaag ccatgaacat tgggtgagcg tgatccgcca gctgattcac ctcggcctgg
    21001 tgacgcaaaa tattgcccag cattctgccc tacaactgac agaggccgcg cgcccggtgc
    21061 tgcgcggcga atcctctttg caacttgccg tgccgcgtat cgtggcgctc aaaccgaaag
    21121 cgatgcagaa atcgttcggc ggcaactatg atcgcaaact gttcgccaaa ttacgcaaac
    21181 tgcgtaaatc gatagccgat gaaagtaatg tcccgccgta cgtggtgttt aacgacgcaa
    21241 ccttgattga gatggctgaa cagatgccga tcaccgccag cgaaatgctc agcgttaacg
    21301 gcgttgggat gcgcaagctg gaacgctttg gcaaaccgtt tatggcgctg attcgtgcgc
    21361 atgttgatgg cgatgacgaa gagtagtcag cagcataaaa aagtgccagt atgaagactc
    21421 cgtaaacgtt tcccccgcga gtcaaatgta tgttgatgtt atttctcacc gtcgccatgg
    21481 tgcacattgt ggcgcttatg agccccggtc ccgatttctt ttttgtctct cagaccgctg
    21541 tcagtcgttc ccgtaaagaa gcgatgatgg gcgtgctggg cattacctgc ggcgtaatgg
    21601 tttgggctgg gattgcgctg cttggcctgc atttgattat cgaaaaaatg gcctggctgc
    21661 atacgctgat tatggtgggc ggtggcctgt atctctgctg gatgggttac cagatgctac
    21721 gtggtgcact gaaaaaagag gcggtttctg cacctgcgcc acaggtcgag ctggcgaaaa
    21781 gtgggcgcag tttcctgaaa ggtttactga ccaatctcgc taatccgaaa gcgattatct
    21841 actttggctc ggtgttctca ttgtttgtcg gtgataacgt tggcactacc gcgcgctggg
    21901 gcatttttgc gctgatcatt gtcgaaacgc tggcgtggtt taccgtcgtt gccagcctgt
    21961 ttgccctgcc gcaaatgcgc cgtggttatc aacgtctggc gaagtggatt gatggttttg
    22021 ccggggcgtt atttgccgga tttggcattc atttgattat ttcgcggtga tgccagacgc
    22081 gtcttcagag taagtcggat aaggcgttta cgccgcatcc gacattattt ttcacgcatg
    22141 cctcgccgat gctaacagcg ctcccaccag cataaacaac gagccgaaaa tcttattcag
    22201 cgccttcatc tgctttggtc ctttaatcca tagagcaatc cgttgagcaa gggtggcgta
    22261 accgatcatc acaataatat cgaccacaat agtggtgacg ccgagcacga tatactgcat
    22321 cagttgcggc tgttgcggca tgatgaattg cggaaatagc gccgccagaa acacaatact
    22381 tttgggattg gtgagattca caaaaactgc gcgctggaac aaatgtcgac gcgattgagt
    22441 agaggccagc gatttaaggt caattgcacc agcggcgcgc cactgctgga ttcccagcca
    22501 aatcaagtaa gccgcgcctg cccacttcaa cacttcaaac gcaatcactg agcgggaaaa
    22561 tagcgtcccc aaccccacgc caaccagcac aatatgaatc gccagtccgg tctgaagccc
    22621 agcaatagac gccaccgcgc cgcgataacc gtggttgagc gaggtggtca tagtgttgat
    22681 tgcaccagag cctggcgaca ggcttaaaat gatcgatgtc agcaggtagg caaaccacca
    22741 ttctaaggtc atgatgaact cccggtgtgt ctatttttgt gccacaatac gctactgtcg
    22801 cagcgttgtg tcaggcacgc taaaaaaaac gattttacgt ggtttaagag gcagattacc
    22861 cgatgtttca gcagcaaaaa gactgggaaa caagagaaaa cgcgtttgct gcttttacca
    22921 tgggaccgct gactgatttc tggcgtcagc gtgatgaagc agagtttact ggtgtggatg
    22981 acattccggt gcgctttgtc cgttttcgcg cacagcacca tgaccgggtg gtagtcatct
    23041 gcccggggcg tattgagagc tacgtaaaat atgcggaact ggcctatgac ctgttccatt
    23101 tggggtttga tgtcttaatc atcgaccatc gcgggcaggg acgttccggt cgcctgttag
    23161 ccgatccgca tctcgggcat gttaatcgct ttaatgatta tgttgatgat ctggcggcat
    23221 tctggcagca ggaggttcag cccggtccgt ggcgtaaacg ctatatactg gcacattcga
    23281 tgggcggtgc gatctccaca ttatttctgc aacgccatcc aggtgtatgt gacgccattg
    23341 cgctaactgc gccaatgttt gggatcgtga ttcgtatgcc gtcatttatg gcacggcaga
    23401 tcctcaactg ggccgaagcg catccacgtt tccgtgatgg ctatgcaata ggcaccgggc
    23461 gctggcgcgc gttgccgttt gctatcaacg tactgaccca cagcagacag cgatatcgac
    23521 gtaacttacg cttctatgct gatgacccaa cgattcgcgt cggtgggccg acctaccatt
    23581 gggtacgcga aagtattctg gctggcgaac aggtgttagc cggtgcgggt gatgacgcca
    23641 cgccaacgct tctcttgcag gctgaagagg aacgcgtggt ggataaccgc atgcatgacc
    23701 gtttttgtga actccgcacc gccgcgggcc atcctgtcga aggaggacgg ccgttggtaa
    23761 ttaaaggtgc ttaccatgag atcctttttg aaaaggacgc aatgcgctca gtcgcgctcc
    23821 acgccatcgt tgattttttc aacaggcata actcacccag cggaaaccgc tctacagagg
    23881 tttaaatttc ttatgtacca ggttgttgcg tctgatttag atggcacgtt actttctccc
    23941 gaccatacgt tatcccctta cgccaaagaa actctgaagc tgctcaccgc gcgcggcatc
    24001 aactttgtgt ttgcgaccgg tcgtcaccac gttgatgtgg ggcaaattcg cgataatctg
    24061 gagattaagt cttacatgat tacctccaat ggtgcgcgcg ttcacgatct ggatggtaat
    24121 ctgatttttg ctcataacct ggatcgcgac attgccagcg atctgtttgg cgtagtcaac
    24181 gacaatccgg acatcattac taacgtttat cgcgacgacg aatggtttat gaatcgccat
    24241 cgcccggaag agatgcgctt ttttaaagaa gcggtgttcc aatatgcgct gtatgagcct
    24301 ggattactgg agccggaagg cgtcagcaaa gtgttcttca cctgcgattc ccatgaacaa
    24361 ctgctgccgc tggagcaggc gattaacgct cgttggggcg atcgcgtcaa cgtcagtttc
    24421 tctaccttaa cctgtctgga agtgatggcg ggcggcgttt caaaaggcca tgcgctggaa
    24481 gcggtggcga agaaactggg ctacagcctg aaggattgta ttgcgtttgg tgacgggatg
    24541 aacgacgccg aaatgctgtc gatggcgggg aaaggctgca ttatgggcag tgcgcaccag
    24601 cgtctgaaag accttcatcc cgagctggaa gtgattggta ctaatgccga cgacgcggtg
    24661 ccgcattatc tgcgtaaact ctatttatcg taatcgttct ttatttggtc agttgtcaac
    24721 ctgatacttc gctacaatgg atacccgtta atcaaagagt tttccattgt ggcgctactt
    24781 atcatcacca cgattctgtg ggccttctcc tttagctttt atggcgagta ccttgcgggg
    24841 cacgtcgata gctattttgc ggtgctggtg cgcgttggcc tggcggcact cgtttttctg
    24901 ccgtttctgc gtacccgtgg caatagcctg aaaacggtcg gcctgtatat gctggtgggc
    24961 gcgatgcagc ttggcgtgat gtatatgctg agtttccgcg cttatctcta cctgacggtt
    25021 tccgagctgc tgctgttcac cgtgctgacg ccgctctaca tcacgctgat ttatgacatc
    25081 atgagtaagc gccgtctgcg ctggggctat gcctttagcg ccttgctggc ggtgattggt
    25141 gccgggatta ttcgctatga tcaggtcacc gaccatttct ggactggctt gctgctggtg
    25201 caactctcca atatcacttt tgccattggc atggtgggtt acaaacgcct gatggaaact
    25261 cgcccgatgc cacagcataa cgcctttgcg tggttctatc ttggcgcgtt tctggtggca
    25321 gtgattgcat ggttcttgct gggaaatgcg cagaaaatgc cgcaaaccac gctgcaatgg
    25381 ggcattctgg tgtttcttgg cgtggtggct tccgggattg gctactttat gtggaactac
    25441 ggcgcgacgc aggtggacgc cggaacgctg ggcattatga ataatatgca cgttccggca
    25501 gggctgctgg taaacctggc tatctggcac caacagccgc actggccaac gtttattaca
    25561 ggcgcgctgg tgatcctggc ctcactgtgg gtgcatcgta agtgggtcgc tccgcgctct
    25621 tcacaaacgg cagatgatcg caggcgtgat tgcgcgctga gcgaataaac gcttccgtaa
    25681 ctggctgacg ctgctcgcca tcgcgcacgg cggcgtacag tcggctccac aagccttcgc
    25741 ccagggtttt ggtcaccacc agaccctggc gctcaaaact ctctactacc caatgcggta
    25801 gcgcggcaat acccatccgc gcggcaacca tctgaatcaa caataaggtg ttatcgacgc
    25861 ttttcagtga cgggctgacg cctgccggct gaagaaaatg ccgccagaca tccagtcgac
    25921 tacgctgcac cggataaatt aatagcgtct cgctggcgag atcttccggt gtaattcgcg
    25981 ttttcgccgc cagtggatgg tcaggtgcta acaccagacg cacttcatag tcgaacatcg
    26041 gcgaataatg caggccactg cgcggcagaa tatcggacgt cattaccaga tccagctctc
    26101 cctgttgcaa ggcgggctgc gggtcaaatg tcacgcccga tttaaaatcc atctctacct
    26161 gcggccagtt cttatggaaa ttttctaacg cgggtgtcag ccactgaata cagctatggc
    26221 actcaatggc aatgcgcaga cgcgtctgct gcggttcatt gcaggcttgc agggcctggc
    26281 taatttgcgg cagtacctgg tttgccagtt gcaacaggat ttctccctgc ggtgtaaagc
    26341 gtagcggctg gctcttacgc acaaatagcc ggaagccaag gcgttgttcc agatcgctaa
    26401 actggtgaga cagggcggat tgcgtctgat gcaacgtcgc cgcagcggct gcgagcgagc
    26461 cgcagttccg caacgcttgt agcgttttca ggtgttttac ttcgatcatg aaagtccttc
    26521 acttcggcat gaataatttg cgcttgagga atatacagta accgccaatt atggatgtgt
    26581 aaacatctgg acggctaaaa tccttcgtct tttaaattta tggtgcgttg gctgcgtttc
    26641 tccaccccgg tcacttactt cagtaagctc ccggggatga ataaacttgc cgccttccct
    26701 aaattcaaaa tccataggat ttacatataa ttagaggaag aaaaaatgac aatattgaat
    26761 cacaccctcg gtttccctcg cgttggcctg cgtcgcgagc tgaaaaaagc gcaagaaagt
    26821 tattgggcgg ggaactccac gcgtgaagaa ctgctggcgg tagggcgtga attgcgtgct
    26881 cgtcactggg atcaacaaaa gcaagcgggt atcgacctgc tgccggtggg cgattttgcc
    26941 tggtacgatc atgtactgac caccagtctg ctgctgggta acgttccggc gcgtcatcag
    27001 aacaaagatg gttcggtaga tatcgacacc ctgttccgta ttggtcgtgg acgtgcgccg
    27061 actggcgaac ctgcggcggc agcggaaatg accaaatggt ttaacaccaa ctatcactac
    27121 atggtgccgg agttcgttaa aggccaacag ttcaaactga cctggacgca gctgctggac
    27181 gaagtggacg aggcgctggc gctgggccac aaggtgaaac ctgtgctgct ggggccggtt
    27241 acctggctgt ggctggggaa agtgaaaggt gaacaatttg accgcctgag cctgctgaac
    27301 gacattctgc cggtttatca gcaagtgctg gcagaactgg cgaaacgcgg catcgagtgg
    27361 gtacagattg atgaacccgc gctggtactg gaactaccac aggcgtggct ggacgcatac
    27421 aaacccgctt acgacgcgct ccagggacag gtgaaactgc tgctgaccac ctattttgaa
    27481 ggcgtaacgc caaatctcga cacgattact gcgctgcctg ttcagggtct gcatgttgac
    27541 ctcgtacatg gtaaagatga cgttgctgaa ctgcacaagc gcctgccttc tgactggttg
    27601 ctgtctgcgg gtctgatcaa tggtcgtaac gtctggcgcg ccgatcttac cgagaaatat
    27661 gcgcaaatta aggacattgt cggcaaacgt gatttgtggg tggcatcttc ctgctcgttg
    27721 ctgcacagcc ccatcgacct gagcgtggaa acgcgtcttg atgcagaagt gaaaagctgg
    27781 tttgccttcg ccctacaaaa atgccatgaa ctggcactgc tgcgcgatgc gctgaacagt
    27841 ggtgacacgg cagctctggc agagtggagc gccccgattc aggcacgtcg tcactctacc
    27901 cgcgtacata atccggcggt agaaaagcgt ctggcggcga tcaccgccca ggacagccag
    27961 cgtgcgaatg tctatgaagt gcgtgctgaa gcccagcgtg cgcgttttaa actgccagcg
    28021 tggccgacca ccacgattgg ttccttcccg caaaccacgg aaattcgtac cctgcgtctg
    28081 gatttcaaaa agggcaatct cgacgccaac aactaccgca cgggcattgc ggaacatatc
    28141 aagcaggcca ttgttgagca ggaacgtttg ggactggatg tgctggtaca tggcgaggcc
    28201 gagcgtaatg acatggtgga atactttggc gagcacctcg acggatttgt ctttacgcaa
    28261 aacggttggg tacagagcta cggttcccgc tgcgtgaagc caccgattgt cattggtgac
    28321 attagccgcc cggcaccgat taccgtggag tgggcgaagt atgcgcaatc gctgaccgac
    28381 aaaccggtga aagggatgct gacggggccg gtgaccatac tctgctggtc gttcccgcgt
    28441 gaagatgtca gccgtgaaac catcgccaaa cagattgcgc tggcgctgcg tgatgaagtg
    28501 gccgatctgg aagccgctgg aattggcatc atccagattg acgaaccggc gctgcgcgaa
    28561 ggtttaccgc tgcgtcgtag cgactgggat gcgtatctcc agtggggcgt agaggccttc
    28621 cgtatcaacg ccgccgtggc gaaagatgac acacaaatcc acactcacat gtgttattgc
    28681 gagttcaacg acatcatgga ttcgattgcg gcgctggacg cagacgtcat caccatcgaa
    28741 acctcgcgtt ccgacatgga gttgctggag tcgtttgaag agtttgatta tccaaatgaa
    28801 atcggtcctg gcgtctatga cattcactcg ccaaacgtac cgagcgtgga atggattgaa
    28861 gccttgctga agaaagcggc aaaacgcatt ccggcagagc gcctgtgggt caacccggac
    28921 tgtggcctga aaacgcgcgg ctggccagaa acccgcgcgg cactggcgaa catggtgcag
    28981 gcggcgcaga acttgcgtcg ggggtaaaat ccaaaccggg tggtaatacc acccggtctt
    29041 ttctcattac agcgacttct tcccaccata ctgcttaaac cattccagca tacgctgcca
    29101 gccatcttct gcagatgcgg catgatagct cgggcgataa tcagcgttga atgcatgccc
    29161 ggcgtccggg tacacgataa tctctgcttt cgcattagca gcccgcagcg cctggcgcat
    29221 ggtttcaacg ctctcctgcg gaatgctgtt atcctgacca ccatataagc cgagaatcgg
    29281 cgcgttaaga tcggttgcga tatcaacagg ttgtttcggt gaattcagcg acttgtcgcc
    29341 cgtcagtttg ccgtaccacg ccactgcggc ttttagctgt ggattatgcg cggcatacag
    29401 ccaggtgata cgtccacccc agcagaatcc ggtgatcatt aaacgatgaa catcgccgcc
    29461 gttgcgggaa gcccaactgg cgacatgatc gagatcggcc agcacctgcg agtcaggcac
    29521 ttttgctacc agaccgctaa gcaacgtggg gatatcggca aaatcattcg gatcgccttc
    29581 gcggaagtaa agttcaggtg cgatagccag atacccctcc agcgccagac ggcgacaaat
    29641 gtcgcggata tgttcatgca cgccaaaaat ttcctgcact acaatgacca ctggcagtgg
    29701 gccatcgctt tgctttggtc tggcatggta agcaggcatg ttatcccctt gtgaagggat
    29761 agaggtgaag cccgccacaa tcgcgtcgtc cggggtctga acgatggtcg aagcgagagg
    29821 cgatgcagca ggtgcaaatc cagattgttg tgttgttgcc atggtattct ccgtaccctt
    29881 ataaaaatgt tgcgcaatgt taactatagt cagcatgcaa caaatcacat tgcctgaatc
    29941 ggctcatctt ttatgcagtc ctgcagaatg aagggtgatt tatgtgattt gcatcacttt
    30001 tggtgggtaa atttatgcaa cgcatttgcg tcatggtgat gagtatcacg aaaaaatgtt
    30061 aaacccttcg gtaaagtgtc tttttgcttc ttctgactaa accgattcac agaggagttg
    30121 tatatgtcca agtctgatgt ttttcatctc ggcctcacta aaaacgattt acaaggggct
    30181 acgcttgcca tcgtccctgg cgacccggat cgtgtggaaa agatcgccgc gctgatggat
    30241 aagccggtta agctggcatc tcaccgcgaa ttcactacct ggcgtgcaga gctggatggt
    30301 aaacctgtta tcgtctgctc taccggtatc ggcggcccgt ctacctctat tgctgttgaa
    30361 gagctggcac agctgggcat tcgcaccttc ctgcgtatcg gtacaacggg cgctattcag
    30421 ccgcatatta atgtgggtga tgtcctggtt accacggcgt ctgtccgtct ggatggcgcg
    30481 agcctgcact tcgcaccgct ggaattcccg gctgtcgctg atttcgaatg tacgactgcg
    30541 ctggttgaag ctgcgaaatc cattggcgcg acaactcacg ttggcgtgac agcttcttct
    30601 gataccttct acccaggtca ggaacgttac gatacttact ctggtcgcgt agttcgtcac
    30661 tttaaaggtt ctatggaaga gtggcaggcg atgggcgtaa tgaactatga aatggaatct
    30721 gcaaccctgc tgaccatgtg tgcaagtcag ggcctgcgtg ccggtatggt agcgggtgtt
    30781 atcgttaacc gcacccagca agagatcccg aatgctgaga cgatgaaaca aaccgaaagc
    30841 catgcggtga aaatcgtggt ggaagcggcg cgtcgtctgc tgtaattctc ttctcctgtc
    30901 tgaaggccga cgcgttcggc cttttgtatt tttgcgtagc gcctcgcagg aaatgccttt
    30961 ccaactggac gtttgtacag cacaattcta ttttgtgcgg gtaagttgtt gcgtcaggag
    31021 gcgttgtgga tttctcaatc atggtttacg cagttattgc gttggtgggt gtggcaattg
    31081 gctggctgtt tgccagttat caacatgcgc agcaaaaagc cgagcaatta gctgaacgtg
    31141 aagagatggt cgcggagtta agcgcggcaa aacaacaaat tacccaaagc gagcactggc
    31201 gtgcagagtg cgagttactc aataacgaag tgcgcagcct gcaaagtatt aacacctctc
    31261 tggaggccga tctgcgtgaa gtaaccacgc ggatggaagc cgcacagcaa catgctgacg
    31321 ataaaattcg ccagatgatt aacagcgagc agcgcctcag tgagcagttt gaaaacctcg
    31381 ccaaccgtat ttttgagcac agcaatcgcc gggttgatga gcaaaaccgt cagagtctga
    31441 acagcctgtt gtcgccgcta cgtgaacaac tggacggttt ccgccgtcag gttcaggaca
    31501 gcttcggtaa agaagcacaa gaacgccata ccctgaccca cgaaattcgc aatctccagc
    31561 aactcaacgc gcaaatggcc caggaagcga tcaacctgac gcgcgcgctg aaaggcgaca
    31621 ataaaaccca gggcaactgg ggcgaggtag tattgacgcg ggtgctggag gcttccggtc
    31681 tgcgtgaagg gtatgaatat gaaacccagg tcagcatcga aaatgacgcc cgctcgcgga
    31741 tgcagccgga tgtcatcgtg cgcctgccgc agggaaaaga tgtggtgatc gacgccaaaa
    31801 tgacgctggt cgcctatgaa cgctatttta acgccgaaga cgactacacc cgcgaaagcg
    31861 cgctacagga acatatcgcg tcggtgcgta accatatccg tttgctggga cgcaaagatt
    31921 atcaacagct gccggggctg cgaactctgg attacgtgct gatgtttatt cccgttgaac
    31981 ccgctttttt actggcgctt gaccgccagc cggagctgat caccgaagcg ttgaaaaaca
    32041 acatcatgct ggttagcccg actacgctgc tggtggcgct gcgcactatc gccaacctgt
    32101 ggcgttatga gcatcaaagc cgcaacgccc agcaaatcgc cgatcgtgcc agcaagctgt
    32161 acgacaagat gcgtttgttc atcgatgaca tgtccgcgat tggtcaaagt ctcgacaaag
    32221 cgcaggataa ttatcggcag gcaatgaaaa aactctcttc agggcgcgga aatgtgctgg
    32281 cgcaggcaga agcgtttcgc ggtttaggag tagaaattaa acgcgagatt aatccggatt
    32341 tggctgaaca ggcggtgagc caggatgaag agtatcgact tcggtcggtt ccggagcagc
    32401 cgaatgatga agcttatcaa cgcgatgatg aatataatca gcagtcgcgc tagcccattg
    32461 ggagtagtta agccgggtag aaatctaggg catcgacgcc caatctgtta cacttctgga
    32521 acaatttttt gatgagcagg cattgagatg gtggataagt cacaagaaac gacgcacttt
    32581 ggttttcaga ccgtcgcgaa ggaacaaaaa gcggatatgg tcgcccacgt tttccattcc
    32641 gtggcatcaa aatacgatgt catgaatgat ttgatgtcat ttggtattca tcgtttgtgg
    32701 aagcgattca cgattgattg cagcggcgta cgccgtgggc agaccgtgct ggatctggct
    32761 ggtggcaccg gcgacctgac agcgaaattc tcccgcctgg tcggagaaac tggcaaagtg
    32821 gtccttgctg atatcaatga atccatgctc aaaatgggcc gcgagaagct gcgtaatatc
    32881 ggtgtgattg gcaacgttga gtatgttcag gcgaacgctg aggcgctgcc gttcccggat
    32941 aacacctttg attgcatcac catttcgttt ggtctgcgta acgtcaccga caaagataaa
    33001 gcactgcgtt caatgtatcg cgtgctgaaa cccggcggcc gcctgctggt gcttgagttc
    33061 tcgaagccaa ttatcgagcc gctgagcaaa gcctatgatg catactcctt ccatgtgctg
    33121 ccgcgtattg gctcactggt cgcgaacgac gccgacagct accgttatct ggcagaatcc
    33181 atccgtatgc atcccgatca ggataccctg aaagccatga tgcaggatgc cggattcgaa
    33241 agtgtcgact actacaatct gacggcaggg gttgtggcgc tgcatcgtgg ttataagttc
    33301 tgacaggaga ccggaaatgc cttttaaacc tttagtgacg gcaggaattg aaagtctgct
    33361 caacaccttc ctgtatcgct cacccgcgct gaaaacggcc cgctcgcgtc tgctgggtaa
    33421 agtattgcgc gtggaggtaa aaggcttttc gacgtcattg attctggtgt tcagcgaacg
    33481 ccaggttgat gtactgggcg aatgggcagg cgatgctgac tgcaccgtta tcgcctacgc
    33541 cagtgtgttg ccgaaacttc gcgatcgcca gcagcttacc gcactgattc gcagtggtga
    33601 gctggaagtg cagggcgata ttcaggtggt gcaaaacttc gttgcgctgg cagatctggc
    33661 agagttcgac cctgcggaac tgctggcccc ttataccggt gatatcgccg ctgaaggaat
    33721 cagcaaagcc atgcgcggag gcgcaaagtt cctgcatcac ggcattaagc gccagcaacg
    33781 ttatgtggcg gaagccatta ctgaagagtg gcgtatggca cccggtccgc ttgaagtggc
    33841 ctggtttgcg gaagagacgg ctgccgtcga gcgtgctgtt gatgccctga ccaaacggct
    33901 ggaaaaactg gaggctaaat gacgccaggt gaagtacggc gcctatattt catcattcgc
    33961 acttttttaa gctacggact tgatgaactg atccccaaaa tgcgtatcac cctgccgcta
    34021 cggctatggc gatactcatt attctggatg ccaaatcggc ataaagacaa acttttaggt
    34081 gagcgactac gactggccct gcaagaactg gggccggttt ggatcaagtt cgggcaaatg
    34141 ttatcaaccc gccgcgatct ttttccaccg catattgccg atcagctggc gttattgcag
    34201 gacaaagttg ctccgtttga tggcaagctg gcgaagcagc agattgaagc tgcaatgggc
    34261 ggcttgccgg tagaagcgtg gtttgacgat tttgaaatca agccgctggc ttctgcttct
    34321 atcgcccagg ttcataccgc gcgattgaaa tcgaatggta aagaggtggt gattaaagtc
    34381 atccgcccgg atattttgcc ggttattaaa gcggatctga aacttatcta ccgtctggct
    34441 cgctgggtgc cgcgtttgct gccggatggt cgccgtctgc gcccaaccga agtggtgcgc
    34501 gagtacgaaa agacattgat tgatgaactg aatttgctgc gggaatctgc caacgccatt
    34561 cagcttcggc gcaattttga agacagcccg atgctctaca tcccggaagt ttaccctgac
    34621 tattgtagtg aagggatgat ggtgatggag cgcatttacg gcattccggt gtctgatgtt
    34681 gcggcgctgg agaaaaacgg cactaacatg aaattgctgg cggaacgcgg cgtgcaggtg
    34741 ttcttcactc aggtctttcg cgacagcttt ttccatgccg atatgcaccc tggcaacatc
    34801 ttcgtaagct atgaacaccc ggaaaacccg aaatatatcg gcattgattg cgggattgtt
    34861 ggctcgctaa acaaagaaga taaacgctat ctggcagaaa actttatcgc cttctttaat
    34921 cgcgactatc gcaaagtggc agagctacac gtcgattctg gctgggtgcc accagatacc
    34981 aacgttgaag agttcgaatt tgccattcgt acggtctgtg aacctatctt tgagaaaccg
    35041 ctggccgaaa tttcgtttgg acatgtactg ttaaatctgt ttaatacggc gcgtcgcttc
    35101 aatatggaag tgcagccgca actggtgtta ctccagaaaa ccctgctcta cgtcgaaggg
    35161 gtaggacgcc agctttatcc gcaactcgat ttatggaaaa cggcgaagcc tttcctggag
    35221 tcgtggatta aagatcaggt cggtattcct gcgctggtga gagcatttaa agaaaaagcg
    35281 ccgttctggg tcgaaaaaat gccagaactg cctgaattgg tttacgacag tttgcgccag
    35341 ggcaagtatt tacagcacag tgttgataag attgcccgcg agcttcagtc aaatcatgta
    35401 cgtcagggac aatcgcgtta ttttctcgga attggcgcta cgttagtatt aagtggcaca
    35461 ttcttgttgg tcagccgacc tgaatggggg ctgatgcccg gctggttaat ggcaggtggt
    35521 ctgatcgcct ggtttgtcgg ttggcgcaaa acacgctgat tttttcatcg ctcaaggcgg
    35581 gccgtgtaac gtataatgcg gctttgttta atcatcatct accacagagg aacatgtatg
    35641 ggtggtatca gtatttggca gttattgatt attgccgtca tcgttgtact gctttttggc
    35701 accaaaaagc tcggctccat cggttccgat cttggtgcgt cgatcaaagg ctttaaaaaa
    35761 gcaatgagcg atgatgaacc aaagcaggat aaaaccagtc aggatgctga ttttactgcg
    35821 aaaactatcg ccgataagca ggcggatacg aatcaggaac aggctaaaac agaagacgcg
    35881 aagcgccacg ataaagagca ggtgtaatcc gtgtttgata tcggttttag cgaactgcta
    35941 ttggtgttca tcatcggcct cgtcgttctg gggccgcaac gactgcctgt ggcggtaaaa
    36001 acggtagcgg gctggattcg cgcgttgcgt tcactggcga caacggtgca gaacgaactg
    36061 acccaggagt taaaactcca ggagtttcag gacagtctga aaaaggttga aaaggcgagc
    36121 ctcactaacc tgacgcccga actgaaagcg tcgatggatg aactacgcca ggccgcggag
    36181 tcgatgaagc gttcctacgt tgcaaacgat cctgaaaagg cgagcgatga agcgcacacc
    36241 atccataacc cggtggtgaa agataatgaa gctgcgcatg agggcgtaac gcctgccgct
    36301 gcacaaacgc aggccagttc gccggaacag aagccagaaa ccacgccaga gccggtggta
    36361 aaacctgctg cggacgctga accgaaaacc gctgcacctt ccccttcgtc gagtgataaa
    36421 ccgtaaacat gtctgtagaa gatactcaac cgcttatcac gcatctgatt gagctgcgta
    36481 agcgtctgct gaactgcatt atcgcggtga tcgtgatatt cctgtgtctg gtctatttcg
    36541 ccaatgacat ctatcacctg gtatccgcgc cattgatcaa gcagttgccg caaggttcaa
    36601 cgatgatcgc caccgacgtg gcctcgccgt tctttacgcc gatcaagctg acctttatgg
    36661 tgtcgctgat tctgtcagcg ccggtgattc tctatcaggt gtgggcattt atcgccccag
    36721 cgctgtataa gcatgaacgt cgcctggtgg tgccgctgct ggtttccagc tctctgctgt
    36781 tttatatcgg catggcattc gcctactttg tggtctttcc gctggcattt ggcttccttg
    36841 ccaataccgc gccggaaggg gtgcaggtat ccaccgacat cgccagctat ttaagcttcg
    36901 ttatggcgct gtttatggcg tttggtgtct cctttgaagt gccggtagca attgtgctgc
    36961 tgtgctggat ggggattacc tcgccagaag acttacgcaa aaaacgcccg tatgtgctgg
    37021 ttggtgcatt cgttgtcggg atgttgctga cgccgccgga tgtcttctcg caaacgctgt
    37081 tggcgatccc gatgtactgt ctgtttgaaa tcggtgtctt cttctcacgc ttttacgttg
    37141 gtaaagggcg aaatcgggaa gaggaaaacg acgctgaagc agaaagcgaa aaaactgaag
    37201 aataaattca accgcccgtc agggcggttg tcatatggag tacaggatgt ttgatatcgg
    37261 cgttaatttg accagttcgc aatttgcgaa agaccgtgat gatgttgtag cgtgcgcttt
    37321 tgacgcggga gttaatgggc tactcatcac cggcactaac ctgcgtgaaa gccagcaggc
    37381 gcaaaagctg gcgcgtcagt attcgtcctg ttggtcaacg gcgggcgtac atcctcacga
    37441 cagcagccag tggcaagctg cgactgaaga agcgattatt gagctggccg cgcagccaga
    37501 agtggtggcg attggtgaat gtggtctcga ctttaaccgc aacttttcga cgccggaaga
    37561 gcaggaacgc gcttttgttg cccagctacg cattgccgca gatttaaaca tgccggtatt
    37621 tatgcactgt cgcgatgccc acgagcggtt tatgacattg ctggagccgt ggctggataa
    37681 actgcctggt gcggttcttc attgctttac cggcacacgc gaagagatgc aggcgtgcgt
    37741 ggcgcatgga atttatatcg gcattaccgg ttgggtttgc gatgaacgac gcggactgga
    37801 gctgcgggaa cttttgccgt tgattccggc ggaaaaatta ctgatcgaaa ctgatgcgcc
    37861 gtatctgctc cctcgcgatc tcacgccaaa gccatcatcc cggcgcaacg agccagccca
    37921 tctgccccat attttgcaac gtattgcgca ctggcgtgga gaagatgccg catggctggc
    37981 tgccaccacg gatgctaatg tcaaaacact gtttgggatt gcgttttaga gtttgcggaa
    38041 ctcggtattc ttcacactgt gcttaatctc tttattaata agattaagca atagcatgga
    38101 gcgagcctca ccatcgggtt cggtgaaaat ggcctgaaag ccttcgaacg cgccttcggt
    38161 aataatcacc ttatcacccg gataaggggt tgccggatcg acaatgtctt tcggtttata
    38221 taccgatagc tgatgaataa ccgccgatgg gactatcgct ggcgacgcgc caaagcgcac
    38281 gaagtggctg acaccgcggg tcgcgttgat agtcgtggta tgaatcactt ctgggtcaaa
    38341 ttccacaaac aggtagttgg ggaacaatgg ctcactgact gcagtacgtt ttccacgcac
    38401 gattttttcc agggtgatca tcggtgccag gcaattcaca gcctgtcttt cgaggtgttc
    38461 ctgggcacgt tgaagttgcc cgcgcttgca gtacagtaaa taccaggatt gcataatgac
    38521 tcttatccgt ttaatcgggg cgcaaggata gcaaaagctt tacgctaagt taattatatt
    38581 ccccggtttg cgttataccg tcagagttca cgctaattta acaaatttac agcatcgcaa
    38641 agatgaacgc cgtataatgg gcgcagatta agaggctaca atggacgcca tgaaatataa
    38701 cgatttacgc gacttcttga cgctgcttga acagcagggt gagctaaaac gtatcacgct
    38761 cccggtggat ccgcatctgg aaatcactga aattgctgac cgcactttgc gtgccggtgg
    38821 gcctgcgctg ttgttcgaaa accctaaagg ctactcaatg ccggtgctgt gcaacctgtt
    38881 cggtacgcca aagcgcgtgg cgatgggcat ggggcaggaa gatgtttcgg cgctgcgtga
    38941 agttggtaaa ttattggcgt ttctgaaaga gccggagccg ccaaaaggtt tccgcgacct
    39001 gtttgataaa ctgccgcagt ttaagcaagt attgaacatg ccgacaaagc ggctgcgtgg
    39061 tgcgccctgc caacaaaaaa tcgtctctgg cgatgacgtc gatctcaatc gcattcccat
    39121 tatgacctgc tggccggaag atgccgcgcc gctgattacc tgggggctga cagtgacgcg
    39181 cggcccacat aaagagcggc agaatctggg catttatcgc cagcagctga ttggtaaaaa
    39241 caaactgatt atgcgctggc tgtcgcatcg cggcggcgcg ctggattatc aggagtggtg
    39301 tgcggcgcat ccgggcgaac gtttcccggt ttctgtggcg ctgggtgccg atcccgccac
    39361 gattctcggt gcagtcactc ccgttccgga tacgctttca gagtatgcgt ttgccggatt
    39421 gctacgtggc accaagaccg aagtggtgaa gtgtatctcc aatgatcttg aagtgcccgc
    39481 cagtgcggag attgtgctgg aagggtatat cgaacaaggc gaaactgcgc cggaagggcc
    39541 gtatggcgac cacaccggtt actataatga agtcgatagt ttcccggtat ttaccgtgac
    39601 gcatattacc cagcgtgaag atgcgattta ccattccacc tataccgggc gtccgccaga
    39661 tgagcccgcg gtgctgggtg tcgcactgaa cgaagtgttt gtgccgattc tgcaaaaaca
    39721 gttcccggaa attgtcgatt tttacctgcc gccggaaggc tgctcttatc gcctggcggt
    39781 agtgacaatc aaaaaacagt acgccggaca cgcgaagcgc gtcatgatgg gcgtctggtc
    39841 gttcttacgc cagtttatgt acactaaatt tgtgatcgtt tgcgatgatg acgttaacgc
    39901 acgcgactgg aacgatgtga tttgggcgat taccacccgt atggacccgg cgcgggatac
    39961 tgttctggta gaaaatacgc ctattgatta tctggatttt gcctcgcctg tctccgggct
    40021 gggttcaaaa atggggctgg atgccacgaa taaatggccg ggggaaaccc agcgtgaatg
    40081 gggacgtccc atcaaaaaag atccagatgt tgtcgcgcat attgacgcca tctgggatga
    40141 actggctatt tttaacaacg gtaaaagcgc ctgatgcgcg tttgttttgc cctatttatc
    40201 gatccgacag agaaagcgca tgacaacctt aagctgtaaa gtgacctcgg tagaagctat
    40261 cacggatacc gtatatcgtg tccgcatcgt gccagacgcg gccttttctt ttcgtgctgg
    40321 tcagtatttg atggtagtga tggatgagcg cgacaaacgt ccgttctcaa tggcttcgac
    40381 gccggatgaa aaagggttta tcgagctgca tattggcgct tctgaaatca acctttacgc
    40441 gaaagcagtc atggaccgca tcctcaaaga tcatcaaatc gtggtcgaca ttccccacgg
    40501 agaagcgtgg ctgcgcgatg atgaagagcg tccgatgatt ttgattgcgg gcggcaccgg
    40561 gttctcttat gcccgctcga ttttgctgac agcgttggcg cgtaacccaa accgtgatat
    40621 caccatttac tggggcgggc gtgaagagca gcatctgtat gatctctgcg agcttgaggc
    40681 gctttcgttg aagcatcctg gtctgcaagt ggtgccggtg gttgaacaac cggaagcggg
    40741 ctggcgtggg cgtactggca ccgtgttaac ggcggtattg caggatcacg gtacgctggc
    40801 agagcatgat atctatattg ccggacgttt tgagatggcg aaaattgccc gcgatctgtt
    40861 ttgcagtgag cgtaatgcgc gggaagatcg cctgtttggc gatgcgtttg catttatctg
    40921 agatataaaa aaacccgccc ctgacaggcg ggaagaacgg caactaaact gttattcagt
    40981 ggcatttaga tctatgacgt atctggcaaa ccatgcccga tgcgacgctg tcgcgtctta
    41041 tcgtgcctac aaatagtccg aaccgtaggc cggataaggc gtttacgccg catccggcaa
    41101 ttggtgcatg atgcctgatg cgacgctggc gcgtcttatc aggcctacat tggtgccgga
    41161 tcggtagacc ggataaggcg ttcacgccgc atccggcaag tggttaaacc cgctcaaaca
    41221 ccgtcgcaat accctgaccc agaccgatac acatcgtcgc cagaccaaac tgaacgtctt
    41281 tgcgttccat cagattcagc agcgtggtgc tgatacgcgc accggaacaa cccagcggat
    41341 gacccagcgc gatcgcgcca ccgttgaggt tgatcttctc gtcaatctgc tcaattagtc
    41401 ccagatcttt aatacatggc aggatctgcg cggcaaaggc ttcgttcatt tcaaacacgc
    41461 cgatatcgct ggcagaaagc cccgcttttt tcagcgccag tttcgaggcc ggaaccgggc
    41521 cgtaacccat aatcgatggg tcacaaccaa cgaccgccat cgaacgcaca cgagcgcgcg
    41581 gcttaagacc taattcatgg gcgcggcttt cactcatcac cagcatggca gctgcgccat
    41641 cggaaagtgc agaagatgtg cccgccgtta ccataccgtt tactggatca aacgccggac
    41701 gcagcgtggc gagggcttcc acggtggttt ccgggcgaat cacttcgtcg taattaaact
    41761 gcttcaggac gccgtcggca tcgtgaccac cggtcgggat gatttcattt ttaaatgcgg
    41821 ccgactgcgt ggcggcccag gcgcgggcgt gtgaccgcgc ggcaaaggca tcctgcattt
    41881 cacggctgat accgtgcata cgcgccagca tttctgccgt taagcccatc atgcccgccg
    41941 ctttggcaac attgcggctc aggccggggt gaaaatcgac gccgtgactc atcggcacat
    42001 ggcccatatg ctccacgccg ccaaccagac atgcctgcgc atcgccagtc atgatcattc
    42061 gtgctgcgtc atgcagtgcc tgcatggatg aaccacacaa gcgattaacg gtaaccgccg
    42121 ggacagagtg tggtacttct gccagcagcg ccgcgttacg ggcgatatta aaaccctgct
    42181 ccagcgtctg ctgcacacaa ccccagtaaa tatcgtcgag ggccgccgct tccagtgccg
    42241 ggttacgcgc cagcaggcta cgcattaaat gagcggagag atcttctgca cgcacgttac
    42301 gaaaagcacc gcccttcgaa cggcccatcg gggtgcgaat tgcatcgaca atgacaacct
    42361 gttccattgt gactccttaa gccgttttca ggtcgccaac cggacgggct ggctcaaccg
    42421 gaggatagta cggttcgtta tgacgcgctt tattacgcag accttccggc acttcataca
    42481 gcgggccgag gtgctgatat tgctgtgcca tatcgaggta ttttgcgcta ccgagggtgt
    42541 ccagccagcg gaacgcgccg ccgtggaacg gagggaagcc caggccgtag accagcgcca
    42601 tatccgcttc cgccggagtg gcgataatgc cttcctccag acagcgcacc acttcgttga
    42661 ccatcgggat catcatgcgg gcgataatct cttcttcgct gaaatcgcgc ttcggctggc
    42721 tcacttctgc cagcaggtct tcaacggcgg cgtcttcttc tttcttcggc ttacctttgc
    42781 tgtcttcttt ataacgccag aaaccgaggc cgttcttctg accaaagcgg ttggcatcaa
    42841 acagcgcgtc gatggcatcg cggtaatctt tctgcatccg ctgcgggaag cctgctgcca
    42901 tgacagcctg agcgtgatgc gcggtatcaa tgcccacaac gtccagcaga tatgccgggc
    42961 ccatcggcca gccaaactgt ttttccatca ctttgtcgat cttgcggaaa tccgcgccgt
    43021 cgcgcagcag ctggctgaaa ccggcgaaat acgggaacag cacgcggtta acaaagaagc
    43081 cggggcagtc gttaaccaca atcggcgtct tgcccatctt gctcgcccag gcgacaactt
    43141 tcgcgatggt ttcgtcggag cttttctcgc cgcgaataat ttctaccaac ggcattcggt
    43201 ggaccgggtt aaagaagtgc atcccgcaga agttttccgg gcgttccagc gcgttggcca
    43261 gttcgctgat aggaatggtt gaagtgttag acgccagcac ggtatcctgg cgtacttttt
    43321 gttcggtttc tgccagtacg gcttttttca ctttcgggtt ttcaacaacc gcttctacca
    43381 caatatccac gcggtcaaat ccggcgtagt cgagcgttgg gtggattgtg gagatcacgc
    43441 cagccagttt cagaccatcg atcttgccgc gctcaagctg cttgttcagc agtttcgcgg
    43501 cttcggtcat gccgagggtt aacgacttgt cgttgatatc tttcatgaca accggcacgc
    43561 ctttccacgc agactggtaa gcgatgccgc cgcccataat gcctgcaccc agcaccgcgg
    43621 cctgtttcgg ggtttcaacg tctttggtga gtttcttcgc tttgcctttt acatattgat
    43681 cgttaaggaa aatgccgacc agtgcgcggg cttcgttggt atgcgccagc gggacaaaac
    43741 ttttgttttc caggtttaag gcttcttcac gaccaaaacg ggccgcagct tcaatggttt
    43801 ttactgcggt gatgggggcc ggataatgtt tccccgctgt ttgtgcgacc atccctttag
    43861 cgatggtgaa gctcatggtg gcttcaatct tgctcagttt tagtggttcc agcttcggct
    43921 gacgttttgc tttccagtcg aggtcgccgt taatggcctg gcgtaaaacc gcctttgcgc
    43981 cttcaaccag tttttctgct ttgactacgc catccaccag accgattttc agcgcctgat
    44041 ccgcgccgac atctttaccg gcggcaatga tttccagcgc actgtcagcg cccagcatac
    44101 gtggcatacg tacagaaccg ccaaagccag gcatgatgcc cagtttggtt tccggcagac
    44161 cgatgcgcag atccggcgtc gccagacgat aatcggtcgc cagcacgcat tcgcagccac
    44221 cgcccagcgc atagccattg acggcagcaa tggtcggcac cggcagatct tccaggcgat
    44281 taaacacgct attggcaaag tgcagccact gacttaactg ttcttcagga acgaggaaca
    44341 gggacaaaaa ttcggtgata tcagcaccga cgataaaggc tgctttgttc gaacgcagca
    44401 gcagcccttt tagatctgat tgctgttcca gcacgccgat ggcctcgccg aggctggcga
    44461 cggtcgcagt gtcgagttta ttaactgaac ctggggcatc aaataccagt tcggcaatgc
    44521 catcttccag ccagtcaagg tacagggtgt cgcctttgta aagcatgtca gtctcctgaa
    44581 tccgcaaggt gatctggtcg taccagatga gtcgaagtgt gtattttgtg ttaaaaatat
    44641 gcaaacaaaa gattaaagaa atgccgatct gatcacgctc ggcagaaatc acgctctgga
    44701 tgaacgatgt gctaagatgc ggagacttaa ggtcaaaaaa acagaagggt aaaaaatgga
    44761 atcactggcc tcgctctata aaaatcatat agctacctta caagaacgga ctcgcgatgc
    44821 gctggcgcgc ttcaagctgg atgcgttact tattcactcc ggcgagctgt tcaatgtttt
    44881 tctcgacgat catccctatc cgtttaaagt gaacccgcaa ttcaaagcgt gggtgccggt
    44941 aactcaggtg ccaaactgct ggttgctggt ggatggcgtg aacaagccga aactgtggtt
    45001 ctatctgccg gttgattact ggcacaacgt cgaaccgctg ccgacctctt tctggactga
    45061 agatgtggaa gtgatcgcgc tgccgaaagc cgatggcatt ggtagcctgc tgcctgctgc
    45121 gcgcggcaat atcggttata tcggtccggt gccggaacgt gcgctgcaac tgggtattga
    45181 ggccagcaac atcaacccga aaggggttat cgactacctg cattactatc gctccttcaa
    45241 aactgagtac gaactggcct gtatgcgtga agcgcagaaa atggcggtca acggtcaccg
    45301 cgcggcagaa gaagcgttcc gttctggcat gagcgagttc gatatcaaca ttgcctatct
    45361 gaccgcgacc ggtcatcgtg ataccgacgt accttacagc aacattgtgg cgcttaacga
    45421 acacgctgcg gtactgcatt acaccaaact ggaccatcag gcaccggaag agatgcgcag
    45481 cttcctgctg gatgccgggg cagaatataa cggctatgcg gctgacctga cccgtacctg
    45541 gtcggcaaaa agtgacaacg actacgcgca gctggtgaag gacgttaatg atgaacaact
    45601 ggcgctgatc gccaccatga aagcaggcgt cagctatgtg gattaccaca tccagttcca
    45661 tcagcgcatc gccaaactgc tgcgtaaaca tcaaatcatc accgatatga gtgaagaagc
    45721 gatggtcgaa aacgatctta ccgggccgtt tatgccgcat ggtatcggcc atccgctggg
    45781 cctgcaggtg catgacgtcg ctggttttat gcaggatgat agcggtacgc acctcgcggc
    45841 accggcaaaa tatccgtacc tgcgctgcac ccgtattctc cagccgggca tggtgttaac
    45901 catcgaaccg ggtatctact tcatcgaatc gctactggca ccgtggcgtg aagggcagtt
    45961 cagcaagcac ttcaactggc agaaaattga agcactgaaa ccgttcggcg gcattcgtat
    46021 cgaagacaac gtggtgatcc acgaaaacaa cgtggaaaac atgacccggg atctgaaact
    46081 ggcgtgatgg aaagctggtt aattcctgcg gcaccggtca cggtcgttga agagatcaaa
    46141 aagagccgct tcataacgat gttggcgcat accgatggcg ttgaggcggc gaaagcgttt
    46201 gttgaatcgg tgcgggcaga acaccccgat gcccggcacc attgcgtggc gtgggtcgcg
    46261 ggtgcgccgg atgattctca acagctgggt ttctctgacg acggggagcc ggcgggaacg
    46321 gcaggtaaac cgatgctcgc ccagctaatg ggcagcggcg tcggggaaat taccgctgtg
    46381 gtagtgcgct actacggcgg catattgctt ggcaccggtg ggttagtgaa agcgtatggc
    46441 ggcggcgtga atcaggcgct gcgccagcta acgacccaac gcaagacgcc attaaccgaa
    46501 tatactttgc aatgtgaata tcatcagtta accggcattg aagcgttgct ggggcagtgt
    46561 gacggcaaaa ttatcaacag tgattatcag gcattcgttc tgctgcgggt ggcgcttccg
    46621 gcggcgaaag tggctgaatt ttccgcaaag ctggcggatt ttagccgtgg ttcattgcaa
    46681 ttgttagcga ttgaagaata atccccactt cgttttgcag aactaaggaa gcggcagaga
    46741 tgcattttcg cgccattacc cgaatcgttg gactactggt catcttattt tcagggacca
    46801 tgattatccc tgggctggta gcactcatct accgggatgg agcgggccgc gcttttaccc
    46861 agaccttttt tgtcgccctc gccattggct ctatgctgtg gtggccgaac cgcaaagaga
    46921 aaggcgaact taaatcccgt gaggggtttc tgatagtggt gctgttctgg accgtgctgg
    46981 gtagcgtcgg tgcgctccct tttatcttct cggaaagccc gaacctcacg attaccgatg
    47041 cgttttttga atctttctct ggcctgacca ctacgggagc cactacgctg gtggggctgg
    47101 attcgctccc tcacgccatc ctcttttatc gccagatgct gcaatggttt ggcgggatgg
    47161 ggatcatcgt gttggcggtt gcgatactgc ctatcctcgg cgtgggtggg atgcagctct
    47221 atcgcgcaga aatgcccggc ccgctgaaag ataacaaaat gcgcccgcga attgcggaaa
    47281 cggcgaaaac cctgtggttg atttatgtct tgctgaccgt cgcctgtgcg ctggcgttgt
    47341 ggtttgccgg aatggatgcc tttgatgcca tcggccatag ctttgcgact atcgctattg
    47401 gcggcttctc gacacatgat gccagtatcg gttatttcga tagcccgact attaacacta
    47461 tcattgctat cttcctgctg atctccggct gtaactacgg tctgcacttt tcactgttaa
    47521 gtgggcgtag tctgaaggtt tattggcgcg atccggaatt tcgcatgttt atcggcgtac
    47581 agtttacgct ggtggttatt tgtaccctcg tactgtggtt tcataatgtc tacagttcgg
    47641 cgctgatgac aattaaccag gcgtttttcc aggtggtgtc gatggcgaca accgccgggt
    47701 ttacaactga cagcattgcc cgctggccgc tctttttgcc ggtactgctt ttatgttcag
    47761 cctttatcgg cggttgcgcc gggtcaacgg gcggtggcct gaaggtgatc cgcatcctgc
    47821 tgctgtttaa gcaggggaac cgtgagctga aacgactggt gcatccgaac gccgtctata
    47881 gcattaagct ggggaatcgc gcactgccgg aacgtatcct cgaagccgtt tggggatttt
    47941 tctccgccta tgcattggtg tttattgtca gtatgctggc gattatcgcc acgggcgtgg
    48001 atgacttttc tgcctttgcg tcggttgttg cgacattgaa taacctgggg ccagggcttg
    48061 gcgtggttgc tgataacttt accagtatga acccggtggc taaatggatc ctgattgcca
    48121 acatgctgtt tggtcgtctc gaggtcttta cattgctggt gctctttacc ccgactttct
    48181 ggcgtgaatg atggagtaat acgtgaaaac attaattctt ttctcaacaa gggacggaca
    48241 aacgcgcgag attgcctcct acctggcttc ggaactgaaa gaactgggga tccaggcgga
    48301 tgtcgccaat gtgcaccgca ttgaagaacc acagtgggaa aactatgacc gtgtggtcat
    48361 tggtgcttct attcgctatg gtcactacca ttcagcgttc caggaatttg tcaaaaaaca
    48421 tgcgacgcgg ctgaattcga tgccgagcgc cttttactcc gtgaatctgg tggcgcgcaa
    48481 accggagaag cgtactccac agaccaacag ctacgcgcgc aagtttctga tgaactcgca
    48541 atggcgtccc gatcgctgcg cggtcattgc cggggcgctg cgttacccac gttatcgctg
    48601 gtacgaccgt tttatgatca agctgattat gaagatgtca ggcggtgaaa cggatacgcg
    48661 caaagaagtt gtctataccg attgggagca ggtggcgaat ttcgcccgag aaatcgccca
    48721 tttaaccgac aaaccgacgc tgaaataagc ataaagaata aaaaatgcgc ggtcagaaaa
    48781 ttattttaaa tttcctcttg tcaggccgga ataactccct ataatgcgcc accactgaca
    48841 cggaacaacg gcaaacacgc cgccgggtca gcggggttct cctgagaact ccggcagaga
    48901 aagcaaaaat aaatgcttga ctctgtagcg ggaaagcgta ttatgcacac cccgcgccgc
    48961 tgagaaaaag c
//
LOCUS       DAPOAV010000025        48828 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.025, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000025 DAPOAV010000000
VERSION     DAPOAV010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 48828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48828
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.025"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            31..183
                     /gene="hokA"
                     /locus_tag="RN951_001705"
     CDS             31..183
                     /gene="hokA"
                     /locus_tag="RN951_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001135724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokA"
                     /protein_id="HDX2526718.1"
                     /translation="MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQESYELAAFL
                     ACKLKE"
     gene            complement(370..582)
                     /gene="cspA"
                     /locus_tag="RN951_001706"
     CDS             complement(370..582)
                     /gene="cspA"
                     /locus_tag="RN951_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone/antiterminator CspA"
                     /protein_id="HDX2526719.1"
                     /translation="MSGKMTGIVKWFNADKGFGFITPDDGSKDVFVHFSAIQNDGYKS
                     LDEGQKVSFTIESGAKGPAAGNVTSL"
     gene            complement(863..1153)
                     /locus_tag="RN951_001707"
     CDS             complement(863..1153)
                     /locus_tag="RN951_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator"
                     /protein_id="HDX2526720.1"
                     /translation="MEYKDPMHELLSSLEQIVFKDETQKITLTHRTTSCTEIEQLRKG
                     TGLKIDDFARVLGVSVAMVKEWESRRVKPSSAELKLMRLIQANPALSKQLME"
     gene            1587..2297
                     /locus_tag="RN951_001708"
     CDS             1587..2297
                     /locus_tag="RN951_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3053 domain-containing protein"
                     /protein_id="HDX2526721.1"
                     /translation="MATGKSCSRWFAPLAALLMVVSLSGCFDKEGDQRKAFIDFLQNT
                     VMRSGERLPTLTADQKKQFGPFVSDYAILYGYSQQVNQAMDSGLRPVVDSVNAIRVPQ
                     DYVTQSGPLREMNGSLGVLAQQLQNAKLQADAAHSALKQSDDLKPVFDQAFTKVVTTP
                     ADALQPLIPAAQTFTQQLVMVGDYIAQQGTQVSFVANGIQFPTSQQASEYNKLIAPLP
                     AQHQAFNQAWTTAVTATQ"
     gene            complement(2347..3321)
                     /gene="ghrB"
                     /locus_tag="RN951_001709"
     CDS             complement(2347..3321)
                     /gene="ghrB"
                     /locus_tag="RN951_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418009.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrB"
                     /protein_id="HDX2526722.1"
                     /translation="MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFA
                     EAEGLLGSNENVNAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTET
                     VADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMAL
                     AQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLF
                     GAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLS
                     MANVVAVPHIGSATHETRYGMAACAVDNLIDALQGKVEKNCVNPHVAD"
     gene            complement(3425..4084)
                     /locus_tag="RN951_001710"
     CDS             complement(3425..4084)
                     /locus_tag="RN951_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family lipoprotein"
                     /protein_id="HDX2526723.1"
                     /translation="MKKRVYLIAAVVSGALAVSGCTTNPYTGEREAGKSAIGAGLGSL
                     VGAGIGALSSSKKDRGKGALIGAAAGAALGGGVGYYMDVQEAKLRDKMRGTGVSVTRS
                     GDNIILNMPNNVTFDSSSATLKPAGANTLTGVAMVLKEYPKTAVNVIGYTDSTGGHDL
                     NMRLSQQRADSVASALITQGVDASRIRTQGLGPANPIASNSTAEGKAQNRRVEITLSP
                     L"
     gene            4237..6570
                     /gene="bisC"
                     /locus_tag="RN951_001711"
     CDS             4237..6570
                     /gene="bisC"
                     /locus_tag="RN951_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418007.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin sulfoxide reductase"
                     /protein_id="HDX2526724.1"
                     /translation="MANSSSRYSVLTAAHWGPMLVETDGETVFSSRGALATGMENSLQ
                     SAVRDQVHSNTRVRFPMVRKGFLASPENPQGIRGQDEFVRVSWDEALDLIHQQHKRIR
                     EAYGPASIFAGSYGWRSNGVLHKASTLLQRYMALAGGYTGHLGDYSTGAAQAIMPYVV
                     GGSEVYQQQTSWPLVLEHSDVVVLWSANPLNTLKIAWNASDEQGLSYFSALRDSGKKL
                     ICIDPMRSETVDFFGDKMEWVAPHMGTDVALMLGIAHTLVENGWHDEAFLARCTTGYA
                     VFASYLLGESDGIAKTAEWAAEICGVGAAKIRELAAIFHQNTTMLMAGWGMQRQQFGE
                     QKHWMIVTLAAMLGQIGTPGGGFGLSYHFANGGNPTRRSAVLSSMQGSLPGGCDAVDK
                     IPVARIVEALENPGGAYQHNGMNRHFPDIRFIWWAGGANFTHHQDTNRLIRAWQKPEL
                     VVISECFWTAAAKHADIVLPATTSFERNDLTMTGDYSNQHLVPMKQVVPPRYEARNDF
                     DVFAELSERWEKGGYARFTEGKSELQWLETFYNVARQRGASQQVELPPFAEFWQANQL
                     IEMPENPDSERFIRFADFCRDPLAHPLKTASGKIEIFSQRIADYGYPDCPGHPMWLEP
                     DEWQGNAEPEQLQVLSAHPAHRLHSQLNYSSLRELYAVANREPVTIHPDDAQERGIQD
                     GDTVRLWNARGQILAGAVISEGIKPGVICIHEGAWPDLDLTADGICKNGAVNVLTKDL
                     PSSRLGNGCAGNTALAWLEKYNGPELTLTAFEPPASS"
     gene            complement(6539..6979)
                     /locus_tag="RN951_001712"
     CDS             complement(6539..6979)
                     /locus_tag="RN951_001712"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDX2526725.1"
                     /translation="MIREAQRSELPAILELWLESTTWGHPFIKANYWRDCIPLVRDAY
                     LANAQNWVWEEDGKLLGFVSIMEGRFLAAMFVAPKAVRRGIGKALMQYVQQRHPHLML
                     EVYQKNQPAINFYQAQGFHIVDCAWQDETQLPTWIMSWPVVQTL"
     gene            complement(6976..7539)
                     /gene="tag"
                     /locus_tag="RN951_001713"
     CDS             complement(6976..7539)
                     /gene="tag"
                     /locus_tag="RN951_001713"
                     /EC_number="3.2.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HDX2526726.1"
                     /translation="MERCGWVSQDPLYIVYHDNEWGVPETDSKKLFEMICLEGQQAGL
                     SWITVLKKRENYRACFHQFDPVKVAAMQEEDVERLVQDAGIIRHRGKIQAIIGNARAY
                     LQMEQNGEPFVDFVWSFVNHQPQVTQATTLSEIPTSTSASDALSKALKKRGFKFVGTT
                     ICYSFMQACGLVNDHVVGCCCYPGNKP"
     gene            7697..8395
                     /locus_tag="RN951_001714"
     CDS             7697..8395
                     /locus_tag="RN951_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418004.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HDX2526727.1"
                     /translation="MIIKKSGGRWQLSLLASVVISAFFLNTAYAWQQEYIVDTQPGLS
                     TERYTWDSDHQPDYNDILSQRIQSSQRALGLEVNLAEETPVDVTSSMSMGWNFPLYEQ
                     VTTGPVAALHYDGTTTSMYNEFGDSTTTLTDPLWHASVSTLGWRVDSRLGDLRPWAQI
                     SYNQQFGENIWKAQSGLSRMTATNQNGNWLDVTVGADMLLNQNIAAYAALTQAENTTN
                     NSDYLYTMGVSARF"
     gene            8624..9832
                     /locus_tag="RN951_001715"
     CDS             8624..9832
                     /locus_tag="RN951_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2526728.1"
                     /translation="MTPSNYQRTRWLTLIGTIITQFALGSVYTWSLFNGALSAKLDAP
                     VSQVAFSFGLLSLGLAISSSVAGKLQERFGVKRVTMASGILLGLGFFLTAHSDNLMML
                     WLSAGVLVGLADGAGYLLTLSNCVKWFPERKGLISAFAIGSYGLGSLGFKFIDTQLLE
                     TVGLEKTFVIWGAIALLMIVFGATLMKDAPKQEVKTSNGVVEKDYTLAESMRKPQYWM
                     LAVMFLTACMSGLYVIGVAKDIAQSLAHLDVVSAANAVTVISIANLSGRLVLGILSDK
                     IARIRVITIGQVISLVGMAALLFAPLNAVTFFAAIACVAFNFGGTITVFPSLVSEFFG
                     LNNLAKNYGVIYLGFGIGSICGSIIASLFGGFYVTFYVIFALLILSLALSTTIRQPEQ
                     KMLREAHGSL"
     gene            10156..11847
                     /gene="eptB"
                     /locus_tag="RN951_001716"
     CDS             10156..11847
                     /gene="eptB"
                     /locus_tag="RN951_001716"
                     /EC_number="2.7.8.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418002.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid A phosphoethanolamine
                     7''-transferase"
                     /protein_id="HDX2526729.1"
                     /translation="MRYIKSITQQKLSFLLAIYIGLFMNGAVFYRRFGSYAHDFTVWK
                     GISAVVELAATVLVTFFLLRLLSLFGRRSWRILASLVVLFSAGASYYMTFLNVVIGYG
                     IIASVMTTDIDLSKEVVGLNFILWLIAVSALPLILIWNNRCRYTLLRQLRTPGQRIRS
                     LAVVVLAGIMVWAPIRLLDIQQKKVERATGVDLPSYGGVVANSYLPSNWLSALGLYAW
                     ARVDESSDNNSLLNPAKKFTYQAPQNVDDTYVVFIIGETTRWDHMGIFGYERNTTPKL
                     AQEKNLAAFRGYSCDTATKLSLRCMFVRQGGAEDNPQRTLKEQNIFAVLKQLGFSSDL
                     YAMQSEMWFYSNTMADNIAYREQIGAEPRNRGKPVDDMLLVDEMQQSLGRNPDGKHLI
                     ILHTKGSHFNYTQRYPRSFAQWKPECIGVDSGCTKAQMINSYDNSVTYVDHFISSVID
                     QVRDKKAIVFYAADHGESINEREHLHGTPRELAPPEQFRVPMMVWMSDKYLENPANAQ
                     AFAQLKKEADMKVPRRHVELYDTIMGCLGYTSPDGGINENNNWCHIPQAKEAAAN"
     gene            11939..12015
                     /locus_tag="RN951_001717"
     tRNA            11939..12015
                     /locus_tag="RN951_001717"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11973..11975,aa:Pro,seq:cgg)
     gene            12050..12183
                     /locus_tag="RN951_001718"
     ncRNA           12050..12183
                     /ncRNA_class="other"
                     /locus_tag="RN951_001718"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
     gene            12926..14533
                     /gene="dppA"
                     /locus_tag="RN951_001719"
     CDS             12926..14533
                     /gene="dppA"
                     /locus_tag="RN951_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter substrate-binding
                     protein DppA"
                     /protein_id="HDX2526730.1"
                     /translation="MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNP
                     QLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWH
                     DNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDD
                     NTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQY
                     QKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARM
                     KQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSA
                     KNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRM
                     AEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSC
                     AASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTV
                     FEPVRKEVKGYVVDPLGKHHFENVSIE"
     gene            14841..15860
                     /gene="dppB"
                     /locus_tag="RN951_001720"
     CDS             14841..15860
                     /gene="dppB"
                     /locus_tag="RN951_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppB"
                     /protein_id="HDX2526731.1"
                     /translation="MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGI
                     SPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISMKSRIPVWEEFVPRFQATLEL
                     GVCAMIFATAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHW
                     NLTPVSGRVSDMVFLDDSNPLTGFMLIDTAIWGEDGNFIDAVAHMILPAIVLGTIPLA
                     VIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLA
                     GAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPR
                     IRHKK"
     gene            15870..16772
                     /gene="dppC"
                     /locus_tag="RN951_001721"
     CDS             15870..16772
                     /gene="dppC"
                     /locus_tag="RN951_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010426221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppC"
                     /protein_id="HDX2526732.1"
                     /translation="MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVVIVLF
                     IAIFANWIAPYNPAEQFRDALLAPPAWQEGGSMAHLLGTDDVGRDVLSRLMYGARLSL
                     LVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS
                     IGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAP
                     LIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAI
                     LLTVLAFNLMGDGLRDALDPKLKQ"
     gene            16783..17766
                     /gene="dppD"
                     /locus_tag="RN951_001722"
     CDS             16783..17766
                     /gene="dppD"
                     /locus_tag="RN951_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HDX2526733.1"
                     /translation="MALLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGS
                     GKSVSSLAIMGLIDYPGRVMAEKLEFNGQDLQRISEKERRNLVGAEVAMIFQDPMTSL
                     NPCYTVGFQIMEAIKVHQGGNKSTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGGMSQ
                     RVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVA
                     EAAHKIIVMYAGQVVETGDAHAIFHAPRHPYTQALLRALPEFAQDKERLASLPGVVPG
                     KYDRPNGCLLNPRCPYATDRCRAEEPALNMLADGRQSKCHYPLDDAGRPTL"
     gene            17763..18767
                     /gene="dppF"
                     /locus_tag="RN951_001723"
     CDS             17763..18767
                     /gene="dppF"
                     /locus_tag="RN951_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP binding subunit
                     DppF"
                     /protein_id="HDX2526734.1"
                     /translation="MSTQEATLQQPLLQAIDLKKHYPVKKGMFAPERLVKALDGVSFN
                     LERGKTLAVVGESGCGKSTLGRLLTMIEMPTGGELYYQGQDLLKHDPQAQKLRRQKIQ
                     IVFQNPYGSLNPRKKVGQILEEPLLINTSLSKEQRREKALSMMAKVGLKTEHYDRYPH
                     MFSGGQRQRIAIARGLMLDPDVVIADEPVSALDVSVRAQVLNLMMDLQQELGLSYVFI
                     SHDLSVVEHIADEVMVMYLGRCVEKGTKDQIFNNPRHPYTQALLSATPRLNPDDRRER
                     IKLSGELPSPLNPPPGCAFNARCRRRFGPCTQLQPQLKDYGGQLVACFAVDQDENPQR
                     "
     gene            complement(18797..20068)
                     /locus_tag="RN951_001724"
     CDS             complement(18797..20068)
                     /locus_tag="RN951_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HDX2526735.1"
                     /translation="MQHNTLSKHNQKLPFTRYDFGWVLLCIGMAIGAGTVLMPVQIGL
                     KGIWVFITAAIIAYPATWVVQDIYLKTLSESDSCNDYTDIISHYLGKNWGIFLGVIYF
                     LMIIHGIFIYSLSVVFDSASYLKTFGLTDADLSQSLLYKVAIFAVLVAIASGGERLLF
                     KISGPMVVVKVGIIVVFGFAMIPHWNFANITAFPQASVFFRDVLLTIPFCFFSAVFIQ
                     VLNPMNIAYRKREADKVLATRLALRTHRISYITLIAVILFFAFSFTFSISHEEAVSAF
                     EQNISALALAAQVIPGHIIHITSTVLNIFAVLTAFFGIYLGFHEAIKGIILNLLSRII
                     DTKKINSRVLTLAICAFIVITLTIWVSFRVSVLVFFQLGSPLYGIVSCLIPFFLIYKV
                     AQLEKLRGFKAWLILLYGILLCLSPLLKLIE"
     gene            20544..20651
                     /gene="ldrD"
                     /locus_tag="RN951_001725"
     CDS             20544..20651
                     /gene="ldrD"
                     /locus_tag="RN951_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxic polypeptide
                     LdrD"
                     /protein_id="HDX2526736.1"
                     /translation="MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK"
     gene            complement(20738..22417)
                     /gene="bcsG"
                     /locus_tag="RN951_001726"
     CDS             complement(20738..22417)
                     /gene="bcsG"
                     /locus_tag="RN951_001726"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsG"
                     /protein_id="HDX2526737.1"
                     /translation="MTQFTQNTAMPSSLWQYWRGLSGWNFYFLVKFGLLWAGYLNFHP
                     LLNLVFAAFLLMPLPRYSLHRLRHWIALPIGFALFWHDTWLPGPESIMSQGSQVAGFS
                     TDYLIDHVTRFINWQMIGAIFVLLVAWLFLSQWIRITVFVVAILLWLNVLTLAGPSFF
                     LWPAGQPTTTVTTTGGNAAATVAATGGAPVVGDMPAQTAPPTTANLNAWLNNFYNAEA
                     KRKSTFPSSLPADAQPFELLVINICSLSWSDIEAAGLMSHPLWSHFDIEFKNFNSATS
                     YSGPAAIRLLRASCGQTSHTNLYQPANNDCYLFDNLSKLGFTQHLMMGHNGQFGGFLK
                     EVRENGGMQSELMDQTNLPVILLGFDGSPVYDDTAVLNRWLDVTEKDKNSRSATFYNT
                     LPLHDGNHYPGVSKTADYKARAQKFFDELDAFFTELEKSGRKVMVVVVPEHGGALKGD
                     RMQVSGLRDIPSPSITDVPVGVKFFGMKAPHQGAPIVIEQPSSFLAISDLVVRVLDGK
                     IFTEDNVDWKKLTSGLPQTAPVSENSNAVVIQYQDKPYVRLNGGDWVPYPQ"
     gene            complement(22414..22605)
                     /gene="bcsF"
                     /locus_tag="RN951_001727"
     CDS             complement(22414..22605)
                     /gene="bcsF"
                     /locus_tag="RN951_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417994.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsF"
                     /protein_id="HDX2526738.1"
                     /translation="MMTISDIIEIIVVCALIFFPLGYLARHSLRRIRDTLRLFFAKPR
                     YVKPAGTLRRTEKARATKK"
     gene            complement(22602..24173)
                     /gene="bcsE"
                     /locus_tag="RN951_001728"
     CDS             complement(22602..24173)
                     /gene="bcsE"
                     /locus_tag="RN951_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsE"
                     /protein_id="HDX2526739.1"
                     /translation="MRDIVDPVFSIGISSLWDELRHMPAGGVWWFNVDRHEDAISLAN
                     QTIASQAETAHVAVISMDSDPAKIFQLDDSQGPEKIKLFSMLNHEKGLYYLTRDLQCS
                     IDPHNYLFILVCANNAWQNIPAERLRSWLDKMNKWSRLNHCSLLVINPGNNNDKQFSL
                     LLEEYRSLFGLASLRFQGDQHLLDIAFWCNEKGVSARQQLSVQQQNGIWTLVQSEEAE
                     IQPRSDEKRILSNVAVLEGAPPLSEHWQLFNNNEILFNEARTAQAATVVFSLQQNAQI
                     EPLARSIHTLRRQRGSAMKILVRENTASLRATDERLLLACGANMVIPWNAPLSRCLTM
                     IESVQGQKFSRYVPEDITTLLSMTQPLKLRGFQKWDVFCNAVNNMMNNPLLPAHGKGV
                     LVALRPVPGIRVEQALTLCRPNRTGDIMTIGGNRLVLFLSFCRINDLDTALNHIFPLP
                     TGDIFSNRMVWFEDDQISAELVQMRLLAPEQWGMPLPLTQGSKPVINAEHDGRHWRRI
                     PEPMRLLDDAVERSS"
     gene            24446..24634
                     /locus_tag="RN951_001729"
     CDS             24446..24634
                     /locus_tag="RN951_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhjR family protein"
                     /protein_id="HDX2526740.1"
                     /translation="MNNNEPDTLPDPAIGYIFQNDIVALKQAFSLPDIDYADISQREQ
                     LAAALKRWPLLAEFAQQK"
     gene            24646..25398
                     /gene="bcsQ"
                     /locus_tag="RN951_001730"
                     /pseudo
     CDS             24646..25398
                     /gene="bcsQ"
                     /locus_tag="RN951_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709309.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsQ"
     gene            25395..28013
                     /gene="bcsA"
                     /locus_tag="RN951_001731"
     CDS             25395..28013
                     /gene="bcsA"
                     /locus_tag="RN951_001731"
                     /EC_number="2.4.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417990.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-forming cellulose synthase catalytic
                     subunit"
                     /protein_id="HDX2526741.1"
                     /translation="MSILTRWLLIPPVNARLIGRYRDYRRHGASAFSATLGCFWMILA
                     WIFIPLEHPRWQRIRAEHKNLYPHINASRPRPLDPVRYLIQTCWLLIGASRKETPKPR
                     RRAFSGLQNIRGRYHQWMNELPERVSHKTQHLDEKKELGHLSAGARRLILGIIVTFSL
                     ILALICVTQPFNPLAQFIFLMLLWGVALIVRRMPGRFSALMLIVLSLTVSCRYIWWRY
                     TSTLNWDDPVSLVCGLILLFAETYAWIVLVLGYFQVVWPLNRQPVPLPKDMSLWPSVD
                     IFVPTYNEDLNVVKNTIYASLGIDWPKDKLNIWILDDGGREEFRQFAQNVGVKYIART
                     THEHAKAGNINNALKYAKGEFVSIFDCDHVPTRSFLQMTMGWFLKEKQLAMMQTPHHF
                     FSPDPFERNLGRFRKTPNEGTLFYGLVQDGNDMWDATFFCGSCAVIRRKPLDEIGGIA
                     VETVTEDAHTSLRLHRRGYTSAYMRIPQAAGLATESLSAHIGQRIRWARGMVQIFRLD
                     NPLTGKGLKFAQRLCYVNAMFHFLSGIPRLIFLTAPLAFLLLHAYIIYAPALMIALFV
                     LPHMIHASLTNSKIQGKYRHSFWSEIYETVLAWYIAPPTLVALINPHKGKFNVTAKGG
                     LVEEEYVDWVISRPYIFLVLLNLVGVAVGIWRYFYGPPTEMLTVVVSMVWVFYNLIVL
                     GGAVAVSVESKQVRRSHRVEMTMPAAIAREDGHLFSCTVQDFSDGGLGIKINGQAQIL
                     EGQKVNLLLKRGQQEYVFPTQVARVMGNEVGLKLMPLTTQQHIDFVQCTFARADTWAL
                     WQDSYPEDKPLESLLDILKLGFRGYRHLAEFAPSSVKGIFRVLTSLVSWVVSFIPRRP
                     ERSETAQPSDQALAQQ"
     gene            28024..30363
                     /gene="bcsB"
                     /locus_tag="RN951_001732"
     CDS             28024..30363
                     /gene="bcsB"
                     /locus_tag="RN951_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HDX2526742.1"
                     /translation="MKRKLFWICAVAMGMSAFPSFMTQATPATQPLINAEPAVAAQTE
                     QNPQVGQVMPGVQGADAPVVAQNGPSRDVKLTFAQIAPPPGSMVLRGINPNGSIEFGM
                     RSDEVVTKAMLNLEYTPSPSLLPVQSQLKVYLNDELMGVLPVTKEQLGKKTLAQMPIN
                     PLFITDFNRVRLEFVGHYQDVCENPASTTLWLDVGRSSGLDLTYQTLNVKNDLSHFPV
                     PFFDPRDNRTNTLPMVFAGAPDVGLQQASAIVASWFGSRSGWRGQNFPVLYNQLPDRN
                     AIVFATNDKRPDFLRDHPAVKAPVIEMINHPQNPYVKLLVVFGRDDKDLLQAAKGIAQ
                     GNILFRGESVVVNEVKPLLPRKPYDAPNWVRTDRPVTFGELKTYEEQLQSSGLEPAAI
                     NVSLNLPPDLYLMRSTGIDMDINYRYTMPPVKDSSRMDISLNNQFLQSFNLSSKQEAN
                     RLLLRIPVLQGLLDGKTDVSIPALKLGATNQLRFDFEYMNPMPGGSVDNCITFQPVQN
                     HVVIGDDSTIDFSKYYHFIPMPDLRAFANAGFPFSRMADLSQTITVMPKAPNEAQMET
                     LLNTVGFIGAQTGFPAINLTVTDDGSTIQGKDADIMIIGGIPDKLKDDKQIDLLVQAT
                     ESWVKTPMRQTPFPGIVPDESDRAAETRSTLTSSGAMAAVIGFQSPYNDQRSVIALLA
                     DSPRGYEMLNDAVNDSGKRATMFGSVAVIRESGINSLRVGDVYYVGHLPWFERVWYAL
                     ANHPILLAVLAAISVILLAWVLWRLLRIISRRRLNPDNE"
     gene            30370..31476
                     /gene="bcsZ"
                     /locus_tag="RN951_001733"
                     /pseudo
     CDS             30370..31476
                     /gene="bcsZ"
                     /locus_tag="RN951_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417988.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase"
     gene            31458..34931
                     /gene="bcsC"
                     /locus_tag="RN951_001734"
     CDS             31458..34931
                     /gene="bcsC"
                     /locus_tag="RN951_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026226.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsC"
                     /protein_id="HDX2526743.1"
                     /translation="MRKFTLNIFTLSLGLAVMPMVEAAPTAQQQLLEQVRLGEATHRE
                     DLVQQSLYRLELIDPNNPDVVAARFRSLLRQGDIDGAQKQLDRLSQLAPSSNAYKSSR
                     TTMLLSTPDGRQALQQARLQATTGHAEEAVASYNKLFNGAPPEGDIAVEYWSTVAKIP
                     ARRGEAINQLKRINADAPGNTGLQNNLALLLFSSDRRDEGFAVLEQMAKSNAGREGAS
                     KIWYGQIKDMPVSDASVSALKKYLSIFSDGDSVAAAQSQLAEQQKQLADPAFRARAQG
                     LAAVDSGMAGKAIPELQQAVRANPKDSEALGALGQAYSQKGDRANAVANLEKALALDP
                     HSSNNDKWNSLLKVNRYWLAIQQGDAALKANNPDRAERLFQQARNVDNTDSYAVLGLG
                     DVAMARKDYPAAERYYQQTLRMDSGNTNAVRGLANIYRQQSPEKAEAFIASLSASQRR
                     SIDDIERSLQNDRLAQQAEALENQGKWAQAAALQRQRLALDPGSVWITYRLSQDLWQA
                     GQRSQADTLMRNLAQQKSNDPEQVYAYGLYLSGHDQDRAALAHINSLPRAQWNSNIQE
                     LVNRLQSDQVLETANRLRESGKEAEAEAMLRQQPPSTRIDLTLADWAQQRRDYTAARA
                     AYQNVLTREPANADAILGLTEVDIAAGDKAAARSQLAKLPATDNASLNTQRRVALAQA
                     QLGDTAAAQRTFNKLIPQAKSQPPSMESAMVLRDGAKFEAQAGDPTQALETYKDAMVA
                     SGVTTTRPQDNDTFTRLTRNDEKDDWLKRGVRSDAADLYRQQDLNVTLEHDYWGSSGT
                     GGYSDLKAHTTMLQVDAPYSDGRMFFRSDFVNMNVGSFSTNADGKWDDNWGTCTLQDC
                     SGNRSQSDSGASVAVGWRNDVWSWDIGTTPMGFNVVDVVGGISYSDDIGPLGYTVNAH
                     RRPISSSLLAFGGQKDSPSNTGKKWGGVRADGVGLSLSYDKGEANGVWASLSGDQLTG
                     KNVEDNWRVRWMTGYYYKVINQNNRRVTIGLNNMIWHYDKDLSGYSLGQGGYYSPQEY
                     LSFAIPVMWRERTENWSWELGASGSWSHSRTKTMPRYPLMNLIPTDWQEEAARQSNDG
                     GSSQGFGYTARALLERRVTSNWFVGTAIDIQQAKDYAPSHFLLYVRYSAAGWQGDMDL
                     PPQPLIPYADW"
     gene            35013..37001
                     /gene="hmsP"
                     /locus_tag="RN951_001735"
     CDS             35013..37001
                     /gene="hmsP"
                     /locus_tag="RN951_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417986.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator HmsP"
                     /protein_id="HDX2526744.1"
                     /translation="MRVSRSLTIKQMAMVAAVVLVFVFIFCTVLLFHLVQQNRYNTAT
                     QLESIARSVREPLSSAILKGDIPEAEAILASIKPAGVVSRADVVLPNQFQALRKSFIP
                     ERPVPVMVTRLFELPVQISLGVYSLERPANPQPIAYLVLQADSFRMYKFVMSTLSTLV
                     TIYLLLSLILTVAISWCINRLILHPLRNIARELNAIPAKELVGHQLALPRLHQDDEIG
                     MLVRSYNLNQQLLQRHYEEQNENAMRFPVSDLPNKALLMEMLEQVVARKQTTALMIIT
                     CETLRDTAGVLKEAQREILLLTLVEKLKSVLSPRMILAQISGYDFAVIANGVQEPWHA
                     ITLGQQVLTIMSERLPIERIQLRPHCSIGVAMFYGDLTAEQLYSRAISAAFTARHKGK
                     NQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQPQVEMTSGKLVSAEVLLRIQ
                     QPDGSWDLPDGLIDRIECCGLMVTVGHWVLEESCRLLAAWQERGIMLPLSVNLSALQL
                     MHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVAILRPLRNAGVRVALDDF
                     GMGYAGLRQLQHMKSLPIDVLKIDKMFVEGLPGDSSMIAAIIMLAQSLNLQMIAEGVE
                     TEAQRDWLAKAGVGIAQGFLFARPLPIEIFEESYLEEK"
     gene            37184..38470
                     /gene="dctA"
                     /locus_tag="RN951_001736"
     CDS             37184..38470
                     /gene="dctA"
                     /locus_tag="RN951_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylate transporter DctC"
                     /protein_id="HDX2526745.1"
                     /translation="MKTSLFKSLYFQVLTAIAIGILLGHFYPEIGEQMKPLGDGFVKL
                     IKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALIIGLIIVNVVQPG
                     AGMNVDPATLDAKAVAVYADQAKDQGIVAFIMDVIPASVIGAFASGNILQVLLFAVLF
                     GFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGTLVQ
                     LGQLIICFYITCILFVVLVLGSIAKATGFSIFKFIRYIREELLIVLGTSSSESALPRM
                     LDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSQMDIVHQITLLI
                     VLLLSSKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNG
                     VATIVVAKWVKELDHKKLDDVLNNRAPDGKTHELSS"
     gene            38691..40187
                     /locus_tag="RN951_001737"
     CDS             38691..40187
                     /locus_tag="RN951_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDX2526746.1"
                     /translation="MQGTKIRLLAGGLLMMATAGYVQADALQPDPAWQQGTLSNGLQW
                     QVLTTPQRPSDRVEIRLLVNTGSLAESTQQSGYSHAIPRIALTQSGGLDAAQARSLWQ
                     QGIDPKRPMPPVIVSYDTTLFNLSLPNNRNDLLKEALSYLANATGKLTITPETINHAL
                     QSQDMVATWPADTKEGWWRYRLKGSTLLGHDPADPLKQPVEAEKIKDFYQKWYTPDAM
                     TLLVVGNVDARSVVDQINKTFGELKGKRETPAPVPTLSPLRAEAVSIMTDAVRQDRLS
                     IMWDTPWQPIRESAALLRYWRADLAREALFWHVQQALSASNSKDIGLGFDCRVLYLRA
                     QCAINIESPNDKLNSNLNLVARELAKVRDKGLPEEEFNALVAQKKLELQKLFAAYARA
                     DTDILMGQRMRSLQNQVVDIAPEQYQKLRQDFLNSLTVEMLNQDLRQQLSNDMALILL
                     QPKGEPEFNMKALQAVWDQIMAPSTAAATTSVATDDVHPEVTDIPPAQ"
     gene            complement(40283..41212)
                     /gene="kdgK"
                     /locus_tag="RN951_001738"
     CDS             complement(40283..41212)
                     /gene="kdgK"
                     /locus_tag="RN951_001738"
                     /EC_number="2.7.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417983.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygluconokinase"
                     /protein_id="HDX2526747.1"
                     /translation="MSKKIAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPA
                     ALTVHYVTALGTDSFSQQMLDAWHGENVDTSLTQRMENRLPGLYYIETDSTGERTFYY
                     WRNEAAAKFWLESEQSAAICEELANFDYLYLSGISLAILSPTSREKLLSLLRECRANG
                     GKVIFDNNYRPRLWASKEETQQVYQQMLECTDIAFLTLDDEDALWGQQPVEDVIARTH
                     NAGVKEVVVKRGADSCLVSIAGEGLVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLT
                     GGSAEDAAKRGHLTASTVIQYRGAIIPREAMPA"
     gene            41444..42211
                     /gene="pdeH"
                     /locus_tag="RN951_001739"
     CDS             41444..42211
                     /gene="pdeH"
                     /locus_tag="RN951_001739"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417982.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase"
                     /protein_id="HDX2526748.1"
                     /translation="MIRQVIQRISNPEASIESLQERRFWLQCERAYTWQPIYQTCGRL
                     MAVELLTVVTHPLNPSQRLPPDRYFTEITVSHRMEVVKEQIDLLAQKADFFIEHGLLA
                     SVNIDGPTLIALRQQPKILRQIERLPWLRFELVEHIRLPKDSTFASMCEFGPLWLDDF
                     GTGMANFSALSEVRYDYIKIARELFVMLRQSPEGRTLFSQLLHLMNRYCRGVIVEGVE
                     TPEEWRDVQNSPAFAAQGWFLSRPAPIETLNTAVLAL"
     gene            42281..44341
                     /locus_tag="RN951_001740"
     CDS             42281..44341
                     /locus_tag="RN951_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417981.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HDX2526749.1"
                     /translation="MSKAGKITAAISGAFLLLIVVAIILIATFDWNRLKPTINQKVSA
                     ELNRPFAIRGDLGVVWERQKQETGWRSWVPWPHVHAEDIILGNPPDIPEVTMVHLPRV
                     EATLAPLALLTKTVWLPWIKLGKPDARLIRLSEKNNNWTFNLANDDNKDANAKPSAWS
                     FRLDNILFDQGRIAIDDKVSKADLEIFVDPLGKPLPFSEVTGSKGKADKEKVGDYVFG
                     LKAQGRYNGEPLTGTGKIGGMLALRGEGTPFPVQADFRSGNTRVAFDGVVNDPMKMGG
                     VDLRLKFSGDSLGDLYELTGVLLPDTPPFETDGRLVAKIDTEKSSVFDYRGFNGRIGD
                     SDIHGSLVYTTGKPRPKLEGDVESRQLRLADLGPLIGVDSGKGAEKSKRSEQKKGEKS
                     VQPAGKVLPYDRFETDKWDVMDGDVRFKGRRIEHGSSLPISDLSTHIILKNADLRLQP
                     LKFGMAGGSIAANIHLEGDKKPMQGRADIQARRLKLKELMPDVELMQKTLGEMNGDAE
                     LRGSGNSVAALLGNSNGNLKLLMNDGLVSRNLMEIVGLNVGNYIVGAIFGDDEVRVNC
                     AAANLNIANGVARPQIFAFDTENALINVTGTASFASEQLDLTIDPESKGIRIITLRSP
                     LYVRGTFKNPQAGVKAGPLIARGAVAAALATLVTPAAALLALISPSEGEANQCRTILS
                     QMKK"
     gene            complement(44523..45845)
                     /locus_tag="RN951_001741"
     CDS             complement(44523..45845)
                     /locus_tag="RN951_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter"
                     /protein_id="HDX2526750.1"
                     /translation="MQATATTLDHEQEYTPINSRNKVLVASLIGTAIEFFDFYIYATA
                     AVIVFPHIFFPQGDPTAATLQSLATFAIAFVARPIGSAVFGHFGDRVGRKATLVASLL
                     TMGISTVVIGLLPGYATIGIFAPLLLALARFGQGLGLGGEWGGAALLATENAPPRKRA
                     LYGSFPQLGAPIGFFFANGTFLLLSWLLTDEQFMSWGWRVPFIFSAVLVIIGLYVRVS
                     LHESPVFEKVAKAKKQVKIPLGTLLTKHVRVTVLGTFIMLATYTLFYIMTVYSMTFST
                     AAAPVGLGLPRNEVLWMLMMAVIGFGVMVPVAGLLADAFGRRKSMVIITTLIILFALF
                     AFNPLLGSGNPILVFAFLLLGLSLMGLTFGPMGALLPELFPTEVRYTGASFSYNVASI
                     LGASVAPYIAAWLQTNYGLGAVGLYLAAMAGLTLIALLLTHETRHQSL"
     gene            complement(46256..47269)
                     /gene="yhjD"
                     /locus_tag="RN951_001742"
     CDS             complement(46256..47269)
                     /gene="yhjD"
                     /locus_tag="RN951_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YhjD"
                     /protein_id="HDX2526751.1"
                     /translation="MTQENEIKRPIQDLEHEPIKPLDNSEKGSKVSQALETVTTTAEK
                     VQRQPVIAHLIRATERFNDRLGNQFGAAITYFSFLSMIPILMVSFAAGGFVLASHPML
                     LQDIFDKILQNISDPTLAATLKNTINTAVQQRTTVGLVGLAVALYSGINWMGNLREAI
                     RAQSRDVWERSPQDQEKFWVKYLRDFISLIGLLIALIVTLSITSVAGSAQQMIISALH
                     LNSIEWLKPTWRLIGLAISIFANYLLFFWIFWRLPRHRPRKKALIRGTFLAAIGFEVI
                     KIVMTYTLPSLMKSPSGAAFGSVLGLMAFFYFFARLTLFCAAWIATAEYKDDPRMPGK
                     TQP"
     gene            complement(47318..48217)
                     /locus_tag="RN951_001743"
     CDS             complement(47318..48217)
                     /locus_tag="RN951_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417978.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX2526752.1"
                     /translation="MDKIHAMQLFIKVAELESFSRAADFFALPKGSVSRQIQALEHQL
                     GTQLLQRTTRRVKLTPEGMTYYQRAKDVLSNLSELDGLFQQDATSISGKLRIDIPPGI
                     AKSLLLPRLSEFLYLHPGIELELSSHDRPVDILHDGFDCVIRTGALPEDGVIARPLGK
                     LTMVNCASPHYLTRFGYPQSPDDLTSHAIVRYTPHLGVHPLGFEVASVNGVQWFKSGG
                     MLTVNSSENYLTAGLAGLGIIQIPRIAVREALRAGRLIEVLPGYRAEPLSLSLVYPQR
                     RELSRRVNLFMQWLAGVMKEYLD"
     gene            48737..>48828
                     /locus_tag="RN951_001744"
     CDS             48737..>48828
                     /locus_tag="RN951_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HDX2526753.1"
                     /translation="MQIVMFDRQSIFIHGMKISLQQRIPGVSIQG"
BASE COUNT        11615 a        12292 c        13204 g        11717 t
ORIGIN      
        1 ctcgttggaa atcaacacag gaggctggga atgccgcaga aatatagatt actttcttta
       61 atagtgattt gtttcacgct tttatttttc acctggatga taagagattc actgtgtgaa
      121 ttgcatatta aacaggagag ttatgagctg gcggcgtttt tagcctgcaa attgaaagag
      181 taagagtctt cggcgggaaa ttattcccgc cttacttacg gcgttgcgca ttctcattgc
      241 acccaaattt attcttcaca aaaataataa tagattttat tacgcgatcg attatttatt
      301 tcctgaaaac aaataaaaaa atccccgcca aatggcaggg atcttagatt ctgtgctttt
      361 aagcagagat tacaggctgg ttacgttacc agctgccggg cctttagcgc cgctttcgat
      421 ggtgaaggac actttctgac cttcgtccag agatttgtaa ccatcgttct ggatagcaga
      481 gaagtgtacg aacacatctt tagagccatc gtcaggagtg atgaagccga agcctttgtc
      541 agcgttgaac cattttacga taccagtcat tttaccggac atagtgtatt acctttaata
      601 attaagtgtg cctttcggcg atatggcgtg ctttacagat tttgaagcgt taaaggaatg
      661 tgcactacga ggggtatcaa cgataactct tgaagggact tgccttacta cactgcttta
      721 atggtctgta cgtcaaaccg ttgatgtgca ttaagccacg cattggcggg tgatgcaaca
      781 attatttttc atatttatga ttaatcggtt ggaaaacggt cctgtcatca ggaccgtaaa
      841 cagcaataaa gtggataaaa gtctattcca tcaactgctt acttaatgcc gggttggctt
      901 gaatcaaacg catcaatttt agttcggcac ttgaaggctt cacgcgtctg gattcccatt
      961 cctttaccat ggcgactgat acgcccaaaa cccgggcgaa atcatcgatt tttaatcctg
     1021 tcccttttcg taactgctca atttcggtac aggacgttgt tctgtgcgtc agggtaattt
     1081 tctgcgtttc atctttaaaa acaatctgtt ccaggctgct caacagctca tgcattggat
     1141 ctttatattc cattgaaaac tcctcaaatc acactgcggg atcgtgaatt gcatcgaagc
     1201 tcattaagaa tagtcgggaa aagcagacac agcggggtga agtcagggca tgctctggct
     1261 atgattcgat tcagcctgtc atttagcgtg acttatagcc acctaacgat ctgataaatg
     1321 ccgatatatc tcttaccact cctgttttgt aaagatttcg aaaatctaac cttctgcgaa
     1381 ggcgtaaatc tctggctaca aaaaaggcaa cggcactatc attttttaac aatgaaacaa
     1441 caaattaacc ttgtttcatt ttctccatga ttttaccagg aagattacgt agaaagggta
     1501 tcctgcaagc ctgtcctgga ctatccttgt cacgtcagac acgcgtgtgt cgttgtgcgc
     1561 tttttttggg tgaaaggagt aagaaaatgg cgacaggaaa gtcctgctct cgctggtttg
     1621 cgcctcttgc ggcgttatta atggtagtta gcctgagtgg gtgttttgat aaagaaggcg
     1681 atcagcgtaa agcgtttatc gacttcctgc agaatacagt gatgcgtagc ggtgaacgtc
     1741 taccaaccct gactgccgat cagaaaaaac agtttggtcc ttttgtctct gattacgcga
     1801 ttctgtatgg ttattctcag caggtgaatc aggcgatgga ttccggtctg cgcccggttg
     1861 tagacagcgt taacgcaatt cgcgtaccgc aggattacgt tacgcaaagc ggtccgctgc
     1921 gtgaaatgaa cggttcgctg ggtgtgctgg cgcaacaact gcaaaatgcg aagttgcagg
     1981 ccgatgctgc gcactctgcg ctaaaacaga gcgatgattt gaaaccggtc tttgatcagg
     2041 cattcaccaa agtggtaacg acgccagctg atgcattgca accgttgatt ccggcggcac
     2101 aaactttcac gcaacaactg gtgatggttg gagactacat tgctcagcaa ggtactcagg
     2161 tgagctttgt cgcaaatggc atccagttcc cgacttcaca gcaggcaagt gaatataaca
     2221 aactgattgc gccattaccg gcacagcatc aggcgtttaa tcaggcctgg actacagcag
     2281 ttactgcaac ccaataaaga gtaaaagccc gagcgattat cgggctttac tctacgcagt
     2341 cgcggcttag tccgcgacgt gcggattcac acagttcttc tcaacctttc cttgtaacgc
     2401 atcaatcaaa ttatccacgg cacaggcggc catgccataa cgcgtctcat gggtggcaga
     2461 tccaatatgc ggtactgcga cgacgttggc cattgagagc aacggcgaat ctacggacag
     2521 tggctcttgt tcgaagacat ccagcccggc agcgtgaatt tcgcctttct gcaatgctgc
     2581 gatcagtgca ttttcgtcaa ccaccgggcc acgtccggca ttaatgaaaa tggcggagga
     2641 tttcattttg gcgaattgtt ctgcgccaaa cagatgatgc gtctcatcag ttaacggcag
     2701 gatcaggcaa acgaaatctg actcttgtaa cagagtatcc aaatcgcagt agcgggcgtt
     2761 gaagcgttct tctgcttctt tatggtggcg gcgcgcgtta tagaggatgg gcatgttgaa
     2821 gccaaagtgc gcacgttgtg ccagcgccat gccgatccgt cccatcccga caatgcccag
     2881 tgttttatgg tgaacgtcag tgccgtacca gtccgggcct atgctcgcgg tccattcgcc
     2941 tgcttttacc cgttctgcta cctccacaac ccgacgagcg gtagacaaca ccagcgccat
     3001 cagcgtatcg gcgacggttt ctgttaatac ggttggcgtg tgcatcagca gaatttttcg
     3061 ggcggtaagc gcatcgacat caaaattgtc atagccgacg gagatcgttg atgtggcacg
     3121 cagtttcggc attttttcca gcaatgcggc atttacattc tcgtttgaac ccagtaaacc
     3181 ttcagcttcg gcaaaaattg ctgcattttg ttcgacggtt tgtgggctga ggtttgccac
     3241 ctggtgaacg gtgaaatgct cttgcaggcg ttgcagtaaa tcatcaggta aggctttgta
     3301 gaggataacg gacggcttca tgcttctctc cattcactga taaggcgatc accttagcct
     3361 gaaatatgat gaaggaaaac tgaagaatgc caggtgattt ctgcatcacc tggcatgaaa
     3421 gggattacag cgggcttaag gtaatttcta cacggcggtt ttgcgcctta ccttctgcgg
     3481 tgctgttgct ggcgattggg ttagccgggc caaggccctg agtacggatg cggctggcgt
     3541 ccacgccctg ggtgatcaac gcgctggcaa cggaatccgc acgttgctgg gagagacgca
     3601 tgttcaggtc gtgaccaccc gtgctgtcgg tataaccaat cacgttaacc gccgttttcg
     3661 gatactcttt cagtaccatt gccacgccgg tcagggtgtt agcgcccgcc ggtttcaggg
     3721 tcgcgctgct gctgtcgaag gtcacattgt tcggcatatt gaggataatg ttatccccgc
     3781 tgcgggttac gctaacacca gtgccgcgca ttttgtcgcg cagcttcgct tcctgcacat
     3841 ccatgtaata accaacgccg ccgcccagag ctgcgcctgc tgctgcgcca atcagcgcgc
     3901 ctttaccgcg atctttcttc gaagaagaga gcgcaccaat acccgcgccc acgagagagc
     3961 ccagacctgc gccgatagca gatttacctg cttcgcgttc gccggtgtaa gggttagttg
     4021 tgcagccaga taccgccaga gcgccactca ctacggcggc aataagataa acacgtttct
     4081 tcattgttaa tccttaataa cctttttatt ctttgccacg ggttccgtgg cgggagatta
     4141 tgccgcgtga acatgaagat tattcctggg aatactcgga aatttgtaag taatatttaa
     4201 ctgctcaata catctaacct ttcaggagtc ttcggtttgg ccaactcatc ctcacgatat
     4261 tccgttctga ctgccgccca ttgggggccc atgctggttg aaaccgacgg cgaaaccgtg
     4321 tttagctcgc gtggcgcgtt agccacagga atggaaaact ccttgcagag cgcggttcgc
     4381 gaccaggttc acagcaatac gcgggtacga tttccaatgg tgcgaaaagg ctttcttgcg
     4441 tcaccggaaa acccgcaagg cattcgtggg caggatgaat ttgttcgcgt gagttgggat
     4501 gaggcgctgg atcttattca ccaacaacat aaacgcattc gtgaggctta tggtccggca
     4561 tcgatttttg ctggttccta cggctggcgt tcaaacggcg tgctgcataa ggcctcgaca
     4621 ttattacaac gctatatggc gctggcaggc ggttataccg ggcatctggg ggattattcg
     4681 accggcgcgg cacaggcgat catgccgtat gtcgtgggtg gtagtgaagt ttatcaacag
     4741 cagaccagtt ggccgctggt gctggaacat agcgatgtcg tggtgctgtg gagtgctaac
     4801 ccactcaata cgctgaaaat tgcgtggaat gcatccgatg agcaggggct ttcttacttt
     4861 tctgcactgc gtgacagcgg gaaaaagctg atctgcattg atccaatgcg atcggaaacc
     4921 gtcgatttct ttggcgataa aatggagtgg gtggcaccgc acatgggcac cgatgttgcg
     4981 ctgatgctgg ggatcgccca tacgctggtg gaaaatggtt ggcacgacga agcgtttctg
     5041 gcgcgttgca ccacaggtta tgccgtcttc gcctcttatt tgctgggcga gagtgacgga
     5101 atagcgaaaa ccgccgaatg ggcagcagag atttgtggtg ttggcgcagc gaaaatccgc
     5161 gagctggcgg ctattttcca ccaaaatacc accatgctga tggcaggctg gggaatgcag
     5221 cgccaacagt ttggtgagca aaaacactgg atgatcgtca cgctggcagc aatgttgggg
     5281 caaatcggca cacccggcgg cggttttggt ctttcttacc attttgccaa tggtggtaac
     5341 cccacgcggc gttctgcggt gctctcttcc atgcagggca gcttgccggg tggctgcgat
     5401 gcggtggata aaatccctgt tgcccgcatt gttgaagcac tggaaaaccc tggtggcgca
     5461 tatcaacaca acggtatgaa ccgacatttc ccggatattc gttttatctg gtgggcgggc
     5521 ggtgccaact ttactcatca tcaggatacc aatcgcctga tccgtgcctg gcaaaaaccg
     5581 gagctggtgg tgatctctga atgcttctgg acggcggcgg caaaacacgc ggatatcgtt
     5641 ctgcctgcga ctacctcttt tgagcgtaat gatctcacca tgaccggtga ttacagtaat
     5701 cagcatctgg tgccgatgaa gcaagtggtg ccgccacgct atgaagcgcg taatgatttt
     5761 gatgtttttg ccgagttaag tgaacgctgg gagaagggcg gttatgcacg ttttacggaa
     5821 ggaaaaagtg agctgcaatg gctggaaacg ttttataacg ttgcccgaca gcgcggggca
     5881 agccagcagg ttgaattgcc gccatttgct gagttctggc aagccaacca gttaattgag
     5941 atgccggaaa acccggacag cgagcggttt attcgcttcg ctgatttttg ccgcgatccg
     6001 ctggcgcatc cgttaaaaac cgccagcggc aagattgaaa tcttctcaca gcgtattgcc
     6061 gattacggtt acccggattg ccctgggcat ccaatgtggc tggagccgga cgaatggcag
     6121 ggcaatgccg aaccagaaca gttgcaggta ctttctgccc atccggcgca ccgcctgcac
     6181 agccagctga attacagttc tctgcgcgaa ttgtacgcgg tggcaaatcg tgagcctgtc
     6241 accattcatc ctgacgatgc ccaggagcgc ggcatacaag atggcgatac tgttcggttg
     6301 tggaacgcac gcgggcaaat tcttgccgga gcggtcatta gcgagggaat taaacctggc
     6361 gtgatttgca ttcacgaagg ggcatggccg gatctggatt taaccgctga cggtatttgt
     6421 aaaaacggcg cagtgaacgt gctgaccaaa gatctcccca gctcgcggct ggggaatggc
     6481 tgtgcgggta atacggcgct ggcatggctg gaaaaataca acggtccgga actgacactt
     6541 acagcgtttg aaccaccggc cagctcataa tccatgtggg tagttgggtt tcatcctgcc
     6601 atgcgcaatc gacaatgtga aaaccctgtg cctggtaaaa atttatcgcc ggttgatttt
     6661 tttgataaac ctccagcatc aggtggggat ggcgctgctg cacatactgc atcagcgcct
     6721 taccaatacc gcgcctgacg gccttcggtg cgacaaacat cgctgccaga aatcggcctt
     6781 ccataatgct gacaaaaccg agaagcttac cgtcttcttc ccagacccag ttttgcgcgt
     6841 tggcaagata ggcatcccgc accagcggaa tgcagtcacg ccagtaattc gcttttataa
     6901 agggatgccc ccaggttgta ctttccagcc acagttcgag gatcgcgggg agttctgaac
     6961 gttgcgcttc ccgaatcatg gtttatttcc cggatagcaa cagcagccaa ccacatgatc
     7021 attcaccagc ccacatgcct gcataaagga gtaacagatt gtggtgccga caaacttaaa
     7081 accacgtttt ttcagtgcct tagatagggc gtcggaggcg gacgtagatg tgggaatttc
     7141 gctcaacgtt gtggcttgtg tcacctgtgg ctgatgattt acaaacgacc agacaaagtc
     7201 gacaaacggt tcgccgttct gttccatttg caggtacgcc cgcgcattac caataattgc
     7261 ctgaattttc cctcgatggc ggataatccc ggcgtcctgt accagtcttt cgacatcctc
     7321 ttcctgcatt gctgcgacct tcaccggatc gaactgatga aagcaggcgc gatagttttc
     7381 gcgttttttg aggacggtga tccacgataa tccagcctgc tgcccttcaa ggcagatcat
     7441 ttcgaacagt tttttactgt cagtttcagg cacgccccac tcattatcat ggtagacaat
     7501 ataaagcggg tcctgactca cccagccgca acgttccata ctttccctcg ctatgtaccc
     7561 gatcgtaaaa atttcagccg cttttcttga cgcatcggtg aaaaagtcaa tatttaatac
     7621 agggctacta tgcccgatat ccttcataca atgacaataa tattgccgaa ttcggctctt
     7681 ccctggagtc gtgttaatga tcataaaaaa aagcggtggt cgctggcagc taagcctgct
     7741 ggcgagcgtg gtaatcagtg ccttttttct caacacagct tacgcctggc aacaagaata
     7801 tatcgttgat acgcaacccg gactttccac agagcgttac acctgggata gtgatcatca
     7861 acctgattac aacgatattt tgtcgcaacg tattcaaagt agccaaaggg cgctgggact
     7921 ggaagtcaat ctggcggaag aaacccctgt ggatgtgacc agcagtatga gtatgggctg
     7981 gaattttcct ttatatgaac aggttacaac cggcccggtc gcggcattac attacgatgg
     8041 cacaaccacc tcgatgtata acgagtttgg cgacagtact accacgctga ccgatccgtt
     8101 atggcatgcc agcgtgagta ccttaggctg gcgtgttgac tcccggcttg gcgatctccg
     8161 accctgggcg caaatcagct ataatcagca atttggcgag aatatctgga aggcgcaatc
     8221 aggcctgagc cggatgacgg cgacaaacca gaacggcaac tggctggatg tcaccgtagg
     8281 cgctgatatg ttgctcaatc aaaatattgc cgcctatgcc gcgctaactc aggcagaaaa
     8341 taccactaat aatagcgact atctgtatac gatgggggtt agcgccagat tttaacgtaa
     8401 cagtcacaat tgaaaccatt aaataacaat agttgtggcg atagtgggtg ctaacttacc
     8461 aaataataaa tttggtgaat aattgtcgcg tcattcattc ctgaactaag gcatttcatt
     8521 ccgttctgat ggcatttcat gccgtttttc cccaggcata aagtgcactt cgttatggtt
     8581 gtcggcagag atttttcctt tttattactg caggaatact gccatgacac cttcaaatta
     8641 tcagcgtacc cgctggctga cactcatcgg tactatcatt acccagtttg cgctggggtc
     8701 ggtttatacc tggagcctgt ttaatggcgc gctttccgcc aagctggatg cgccggtaag
     8761 ccaggtcgct ttctctttcg gcttgttaag tctggggctg gcaatttcgt cttctgttgc
     8821 gggcaaatta caggaacgtt ttggcgttaa acgcgtcacc atggcttccg gcattttgct
     8881 gggattaggc ttcttcctga cagcgcattc tgacaacctg atgatgctgt ggttaagcgc
     8941 cggtgtgctg gtgggactgg cagatggcgc gggttatctg ctgacgctct ctaactgtgt
     9001 gaagtggttc ccggagcgta aaggtctgat ctccgcgttc gctatcggtt cttatggtct
     9061 gggtagcctg ggtttcaaat ttatcgacac gcagctgctg gaaacggtcg gtctggaaaa
     9121 aacctttgtg atttggggag cgattgcgct gttgatgatt gttttcggcg caacgttaat
     9181 gaaagacgca ccaaaacagg aagtgaaaac cagcaatggt gtggtggaga aagattacac
     9241 gctggcagag tcgatgcgta aaccgcagta ctggatgtta gcggtaatgt tcctgaccgc
     9301 ctgcatgagc ggcctgtacg tgattggggt agcgaaagat atcgcccaaa gtctggcaca
     9361 ccttgatgtg gtttccgcag ccaatgcagt cactgttatt tccatcgcca acctttcagg
     9421 tcgtctggtg ctgggtattc tgtctgacaa aatcgcccgt atccgtgtta ttaccattgg
     9481 tcaggtgata tcgctggtgg gtatggcggc cctgctgttt gcaccattga atgcagtgac
     9541 gttctttgca gcgattgcct gcgtggcatt taactttggc ggcactatta ccgtctttcc
     9601 gtcactggtc agtgagttct ttggcctcaa taacctggcg aaaaactacg gtgtgattta
     9661 tctcggtttc ggtatcggta gcatttgtgg ttcgattatc gcctcactgt ttggcggctt
     9721 ctatgtgacc ttctacgtga ttttcgccct gctgattctg tcattggcgc tttctacgac
     9781 gattcgtcag ccagagcaga aaatgttgcg tgaggcgcat ggctcccttt aatgctcagc
     9841 cgcgagctac tgggcttcag cttccgtgtg catcaaacgc atcaacgaaa tgtataaaca
     9901 atgactcgta aaatttgggc caattaactg gcccttttta ctgctttttg taacgctaaa
     9961 gtctcttttc aaacttgcat ttttgtaaat ttgtgcttca tgcacactct ttccccacac
    10021 tttttccctt tgctgtggtc tacttattcg cgcgtgtaga ttttacttat ctgactacct
    10081 ccgcactttt tccctgccgg gcctgaaaag ccactaagca gggtgttatc acctgtttgt
    10141 ccagggtttg tttgcatgag atacatcaaa tcgattacac agcagaagct gagctttttg
    10201 cttgcaatct atattggcct ttttatgaat ggcgcggttt tttaccgccg cttcggcagc
    10261 tatgcgcacg attttaccgt ctggaaaggc atttctgctg ttgttgaact ggccgccacc
    10321 gtactggtga ccttcttttt actacgtctt ctttcgctgt ttggccgccg cagctggcgt
    10381 attctggcat cgctggtggt gctcttttcc gcaggtgcca gctattacat gaccttcctt
    10441 aatgtggtca ttggttatgg catcatcgct tccgtcatga ccaccgatat cgacctgtca
    10501 aaagaagttg ttggtctgaa ctttattctc tggttaatcg ccgttagtgc attgcctctt
    10561 atccttatct ggaataaccg ctgtcgctac accttgctcc gacaactgcg aaccccaggg
    10621 cagcgtattc gcagcctggc ggtcgtcgta ctggcgggta ttatggtttg ggcaccgatt
    10681 cgtttgctgg atatccagca gaagaaagtg gagagggcga ccggcgttga tttgccgagt
    10741 tatggcggtg tcgtagcgaa ctcttatctg ccatcaaact ggctttctgc gttggggctg
    10801 tatgcctggg cgcgggtcga tgaatcttcc gataataatt cattgcttaa tccggcgaag
    10861 aaattcactt atcaggcacc gcaaaacgtt gatgacactt atgtcgtgtt tatcatcggt
    10921 gaaaccacgc gttgggacca tatgggtatt ttcggctatg agcgtaatac cacgccgaaa
    10981 ctggcccagg agaaaaatct ggcggcgttc cgtggttact cctgtgatac cgcaaccaaa
    11041 ctctcactgc gttgcatgtt tgtacgtcag gggggcgcgg aagataatcc gcagcgcaca
    11101 ttaaaagaac agaacatttt cgcggttctg aagcagttag gattcagttc tgacctctac
    11161 gctatgcaga gcgaaatgtg gttctacagc aacacgatgg cggacaacat tgcttatcgt
    11221 gagcagattg gtgcggagcc acgtaatcgt ggcaagccgg tagatgatat gttgctggta
    11281 gacgaaatgc agcaatcgct agggcgcaac ccggatggta agcatctgat cattctgcat
    11341 accaaaggtt cgcattttaa ctacacccag cgttatccgc gtagcttcgc gcagtggaag
    11401 ccggaatgta ttggtgttga tagcggctgt accaaagcgc agatgatcaa ctcctatgac
    11461 aactcggtga cctatgtgga tcactttatc tccagcgtga ttgatcaggt tcgcgataag
    11521 aaagcgattg tgttctacgc agctgaccac ggtgagtcaa ttaatgaacg cgagcacctg
    11581 cacggcacgc cgcgtgaact ggcaccgccg gagcagttcc gcgtaccgat gatggtctgg
    11641 atgtcagata aatatctgga aaatccggcc aatgcgcagg cgtttgcgca gctgaaaaaa
    11701 gaagccgaca tgaaagtgcc acgccgtcac gtagagctgt acgataccat catgggttgt
    11761 cttggctata cttcaccgga tggtggaatt aacgaaaaca acaactggtg tcacatcccg
    11821 caggcaaaag aggcagcggc taactaagcg gcctgctgac tttctcgccg atcaaaaggc
    11881 attttgctat taagggattg acgagggcgt atctgcgcag taagatgcgc cccgcattcg
    11941 gtgattggcg cagcctggta gcgcacttcg ttcgggacga aggggtcgga ggttcgaatc
    12001 ctctatcacc gaccaaattc gaaaagcctg ctcaacgagc aggctttttt gcatctgcag
    12061 ctcatgagga tgagaacctc cgggggcagg gaggttcgac tcgagcgaag cgagagaacg
    12121 ttgcgccagc aacggcccgc agggcgagcc acgaagtggc gagtaatcct ctatcaccga
    12181 ccaaattcga aaagcctgct caacgagcag gcttttttgc atctgcagct catgaggatg
    12241 agaacctccg ggggcaggga ggttcgactc gacgtaggcc tgataagacg cgtcagcgtc
    12301 gcatcaggca aatgtgccgg ccattgtcgg atgcggcgcg accgccttat tcgacctaca
    12361 cgacacacat ttccctgcca aatttgcgcc ccatatctca ctatccatta acggatttgt
    12421 gacagaaacc attgtctttt tttatatttg cttaaatctt tttttgcgtt acttatggct
    12481 ggccctggca ttttccgctg tgcgttttag cgttcatggt attaatcgct cagatatcca
    12541 ccttttcctc agattttttt cattaaatgc ataaaactta atcaccaaat gttgctaaat
    12601 attaagctga ttgttctggt catgttggag tagcacaaat ttctctgctg caaatagctg
    12661 tttgaagttt ttttaatctt tgtttgtgga ttctcaccgt tggtgtaaat cccggttggc
    12721 tgtattgacg ttttcacatt ctgttgacag attgtaggtc acgaggggca ttttatggag
    12781 gatccgcact gttacactga tgttaattag tacggcatcc ccacctcata acgttgaccc
    12841 gaccgggcaa aaaacaaaaa aggtcaggca gcgacaaccc actgcaaagg gttaaaacaa
    12901 caaacatcac aattggagca gaataatgcg tatttccttg aaaaagtcag ggatgctgaa
    12961 gcttggtctc agcctggtgg ctatgaccgt cgcagcaagt gttcaggcta aaactctggt
    13021 ttattgctca gaaggatctc cggaagggtt taacccgcag ctgtttacct ccggcaccac
    13081 ctatgacgcc tcttccgtcc cgctttataa ccgtctggtt gaatttaaaa tcggcaccac
    13141 cgaagtgatc ccgggcctcg ctgaaaagtg ggaagtcagc gaagacggta aaacctatac
    13201 cttccatctg cgtaaaggtg tgaagtggca cgacaataaa gaattcaaac cgacgcgtga
    13261 actgaacgcc gatgatgtgg tgttctcgtt cgatcgtcag aaaaacgcgc aaaacccgta
    13321 ccataaagtt tctggcggca gctacgaata cttcgaaggc atgggcttgc cagagctgat
    13381 cagtgaagtg aaaaaggtgg acgacaacac cgttcagttt gtgctgactc gcccggaagc
    13441 gccgttcctc gctgacctgg caatggactt cgcctctatt ctgtcaaaag aatatgctga
    13501 tgcgatgatg aaagccggta caccggaaaa actggacctc aacccaatcg gaaccggtcc
    13561 gttccagtta cagcagtatc aaaaagattc ccgtatccgc tacaaagcgt ttgatggcta
    13621 ctggggcacc aaaccgcaga tcgatacgct ggttttctct attacccctg acgcttccgt
    13681 gcgttacgcg aaattgcaga agaatgaatg ccaggtgatg ccgtacccga acccggcaga
    13741 tatcgctcgc atgaagcagg ataaatccat caatctgatg gaaatgccgg ggctgaacgt
    13801 cggttatctc tcgtataacg tgcagaaaaa accactcgat gacgtgaaag ttcgccaggc
    13861 tctgacctac gcggtgaaca aagacgcgat catcaaagcg gtttatcagg gcgcgggcgt
    13921 atcagcgaaa aacctgatcc cgccaaccat gtggggctat aacgacgacg ttcaggacta
    13981 cacctacgat cctgaaaaag cgaaagcctt gctgaaagaa gcgggtctgg aaaaaggttt
    14041 ctccatcgac ctgtgggcga tgccggtaca acgtccgtat aacccgaacg ctcgccgcat
    14101 ggcggagatg attcaggcag actgggcgaa agtcggcgtg caggccaaaa ttgtcaccta
    14161 cgaatggggt gagtacctca agcgtgcgaa agatggcgag caccagacgg taatgatggg
    14221 ctggactggc gataacgggg atccggataa cttcttcgcc accctgttca gctgcgccgc
    14281 ctctgaacaa ggctccaact actcaaaatg gtgctacaaa ccgtttgaag atctgattca
    14341 accggcgcgt gctaccgacg accacaataa acgcgttgaa ctgtacaaac aagcgcaggt
    14401 ggtgatgcac gatcaggctc cggcactgat catcgctcac tccaccgtgt ttgaaccggt
    14461 acgtaaagaa gttaaaggct atgtggttga tccattaggc aaacatcact tcgaaaacgt
    14521 ctctatcgaa taattaaaag ccatacaaga ctgatggcaa aggcaaaaat gcctgatgcg
    14581 ctccgcttat caggcctacg aaaattctgc aatgtattga atttgcacga ttttgtaggc
    14641 cggataaggc gttaacgccg catccggcat aaacaaagcg cactttgtca acaatctgta
    14701 tacccggtgg cgctgtgcct ctgcgtgcag cgccatccgg cagcaatact tcattccctg
    14761 tccgataagg gcgggaattg atttgtgagc aatacagaca cgcagttcca ggctgcgggt
    14821 cactatagag aatccgggtt atgttgcagt ttattctccg acgtttggga ctcgtcatcc
    14881 ccacgtttat cggtattacc cttctcacat ttgcctttgt ccacatgatc ccgggcgatc
    14941 cggtgatgat catggcgggc gaacgtggga tctccccaga gcgtcacgcg cagctgctgg
    15001 ctgaactcgg cttagataaa ccgatgtggc agcagtatct ccattacatt tggggcgtta
    15061 tgcatggcga tctaggcatt tcaatgaaaa gccgcatccc ggtttgggaa gagttcgtgc
    15121 cgcgcttcca ggccacgctg gaacttggcg tctgcgcgat gatttttgct acggcagtcg
    15181 gtattccggt cggcgtgctg gctgcggtta aacgcggttc cattttcgat cacacagcgg
    15241 ttggcctggc gctgacaggt tattcaatgc ctatcttctg gtggggcatg atgctgatca
    15301 tgctggtttc ggtgcactgg aacctgacgc ccgtctccgg tcgcgtgagc gatatggtgt
    15361 tcctcgatga ctccaatccg ttaaccggtt ttatgctaat cgacaccgcc atctggggtg
    15421 aagacggcaa ctttatcgat gccgtcgccc atatgatctt gcctgccatt gtgctgggta
    15481 ctattccgct ggcggtcatt gtgcgtatga cacgctcctc gatgctggaa gtgctgggcg
    15541 aggattacat ccgcaccgcg cgcgccaaag ggctaacccg catgcgggtg attatcgtcc
    15601 atgcgctgcg taacgcgatg ctgccggtgg tgaccgttat cggcctgcag gtgggaacat
    15661 tgctggcggg ggcgattctg accgaaacca tcttctcgtg gcccggtctg ggacgctggt
    15721 tgattgacgc actgcaacgc cgcgactatc cggtagtgca gggcggcgta ttgctggtgg
    15781 cgacgatgat tatcctcgtc aacttgctgg tcgatctgct gtacggcgtg gtgaacccgc
    15841 gtattcgtca taagaagtaa ggggacatca tgtcacaggt tactgaaaat aaagtgatta
    15901 gcgcaccggt gccgatgacc ccgttacagg agttctggca ctattttaaa cgcaacaaag
    15961 gcgcggtcgt cgggctggtt tacgtcgtca tcgtgctgtt catcgcgatc tttgccaact
    16021 ggattgcacc ctataacccg gcggaacagt tccgcgatgc actgctcgcc ccgccagcct
    16081 ggcaggaagg cggcagcatg gcgcacttgc tgggcaccga tgacgtaggc cgtgatgtgc
    16141 tgtcgcgcct gatgtacggt gcgcgcctgt cgctgctggt tggctgtctg gtagttgtgt
    16201 tatcgctgat tatgggcgtt attctcggcc tgatcgccgg ttactttggc ggcctggtcg
    16261 ataacatcat tatgcgcgtg gtcgatatca tgctggcgct gccaagtctg ctgctggcgc
    16321 tggtgctggt ggcaattttc ggcccgtcga ttggtaacgc cgcgctggca ctgaccttcg
    16381 ttgccttgcc gcactatgtg cgcttaaccc gcgccgccgt gctggtggaa gttaaccgcg
    16441 attacgtcac cgcgtctcgc gtggcgggtg ccggggcgat gcgtcagatg tttattaaca
    16501 tcttcccgaa ctgccttgcg ccgctgattg ttcaggcgtc gctcggtttc tctaacgcca
    16561 ttctcgatat ggctgctctt ggtttcctcg gcatgggggc acagccgcca acgcctgagt
    16621 ggggcaccat gctctccgac gtgttgcagt tcgcgcaaag cgcctggtgg gtcgtgacct
    16681 tcccgggtct ggcgatcctg ctgacggtgc tggcatttaa cctgatgggt gacggtctgc
    16741 gtgacgcgct cgatcccaaa ctgaagcagt aagaggttcg agatggcgtt attaaatgta
    16801 gataaattat cggtgcattt cggcgacgaa agcgcgccgt tccgcgccgt agaccgcatc
    16861 agctacagcg taaaacaggg cgaagtggtc gggattgtgg gtgagtccgg ctccggtaag
    16921 tcggtcagtt cactggcgat tatggggctg attgattatc cgggccgcgt aatggcagaa
    16981 aaactggagt ttaacggcca ggatttgcag cgtatctcag aaaaagagcg ccgcaacctg
    17041 gtgggtgccg aagtggcgat gatcttccag gacccgatga ccagccttaa cccgtgctac
    17101 accgtgggtt tccagattat ggaagcgatt aaggtgcatc agggcggcaa caaaagtacc
    17161 cgccgtcagc gagcgattga cctgctgaat caggtcggta ttcccgatcc ggcatcgcgt
    17221 ctggatgttt acccgcatca gctttccggc ggcatgagcc agcgcgtgat gatcgccatg
    17281 gcgattgcct gtcggccaaa actgctgatt gccgatgaac cgaccaccgc gctggacgtg
    17341 accattcagg cgcaaatcat cgaactactg ctggagctac agcagaaaga gaacatggcg
    17401 ctggtgttaa ttacccatga cctggcgctg gtggcggaag cggcacataa aatcatcgtg
    17461 atgtatgcag gccaggtggt ggaaaccggt gatgcgcacg ccatcttcca tgcgccgcgt
    17521 cacccgtata ctcaggcatt gctgcgtgcg ctgccagaat ttgctcagga caaagaacgt
    17581 ctggcgtcgt tgccaggtgt cgttcccggc aagtacgacc gcccgaacgg ctgcctgctt
    17641 aacccgcgct gcccctatgc cactgacaga tgtcgcgctg aagaaccggc gctgaatatg
    17701 ctcgctgacg ggcgtcagtc caaatgccat tacccacttg atgatgccgg gaggccgaca
    17761 ctatgagtac gcaagaggcc accctgcaac aaccgctgtt gcaggctatc gacctgaaaa
    17821 aacattatcc ggtgaagaaa ggcatgttcg cgccggaacg tctggttaaa gcgctggatg
    17881 gcgtttcgtt taaccttgaa cgtggcaaaa cgctggcagt agtgggcgaa tctggctgcg
    17941 gtaaatcgac cctcggtcgg ttgctgacga tgattgaaat gcccaccggt ggcgagctgt
    18001 attaccaggg gcaggatctg cttaagcacg atccgcaggc gcagaagctg cgtcggcaga
    18061 aaatccagat cgtcttccag aacccttacg gttcgctgaa tccgcgtaaa aaagtcgggc
    18121 aaattcttga agagccgctg ctgatcaaca ccagcttaag caaagaacag cgtcgggaaa
    18181 aagccctgtc gatgatggcg aaagtcggcc tgaaaaccga gcactatgac cgctatccgc
    18241 atatgttctc cggcggtcag cgtcagcgta tcgccatcgc ccgtggtctg atgctcgacc
    18301 cggatgtggt gattgccgat gaaccggttt ccgcgctgga tgtttcagtg cgcgcgcagg
    18361 tgctgaatct gatgatggat ttgcagcagg agttggggct gtcttatgtc tttatctccc
    18421 acgacctgtc ggtggtggag cacattgctg atgaagtgat ggtgatgtac ctgggccgct
    18481 gcgtggagaa gggaacgaaa gaccaaatct tcaataaccc gcgccatccg tacactcagg
    18541 cgctactttc cgcgacgccg cgcctgaacc cggacgatcg ccgcgagcgc atcaagctca
    18601 gcggtgaact accaagccca ctgaatccac cgccgggttg cgccttcaac gcccgctgtc
    18661 gtcggcgctt cggcccctgc acccagttgc agccgcagct aaaagactac ggcggtcaac
    18721 tggtagcttg ttttgctgtt gatcaggatg aaaatccgca gcgttaactc acaaaaccgg
    18781 ggccatgcgc tccggtttac tcaatcagct tcaacagtgg cgacaagcat agcaaaatgc
    18841 cgtacagcag aatcagccag gctttaaatc cgcgaagttt ttccagttgt gcgactttat
    18901 agatcaggaa aaacggaatg aggcacgaca caataccata taacgggctt cccaactgaa
    18961 agaacaccag caccgataca cgaaacgaaa cccaaatcgt caacgtaatg acgataaaag
    19021 cgcagatcgc cagagtcagc acgcgtgagt taattttctt ggtatcaata attcggctta
    19081 acagattgag aataatgcct ttaatggcct cgtggaaacc gagataaatg ccaaagaatg
    19141 cggtcagtac ggcaaagata ttaagcaccg tagaggtgat atgaatgata tgcccaggga
    19201 tcacctgcgc ggccagcgcc agtgctgaga tattttgttc aaaggcagaa acggcttctt
    19261 cgtggctaat tgagaaggta aacgaaaagg caaaaaacag gatcaccgcg atgagcgtga
    19321 tataactaat tcggtgggta cgcagcgcga gccgggttgc cagtacttta tccgcttccc
    19381 gtttacgata ggcaatattc attgggttaa gtacctgaat aaatactgca gaaaagaagc
    19441 aaaatggaat ggtaagcaag acatcgcgga aaaagacgga ggcttgcggg aaggcggtta
    19501 tattggcgaa attccagtgc gggatcatcg caaaaccgaa cacgacaata atccctactt
    19561 tgaccaccac cattggcccg gaaatcttaa acagtaatcg ttcaccacca gacgcaatcg
    19621 ccaccagtac ggcgaaaata gcgactttat aaagtagaga ttgtgaaaga tcggcatcgg
    19681 ttaaaccgaa ggttttcagg tacgaggcgc tgtcgaaaac cacggagaga gagtagataa
    19741 aaatcccgtg gataatcatc aaaaagtaga taaccccgag gaaaattccc cagttcttcc
    19801 ccaggtaatg actgataata tcggtgtagt cattacagga atcgctttca gaaagggttt
    19861 ttaaataaat gtcctgcact acccaggtgg caggataagc aatgatcgct gcggtaataa
    19921 atacccaaat tcccttcaag ccaatttgta ctggcatcag cacggttccg gcaccaatcg
    19981 ccatgcctat gcataataaa acccagccga agtcgtagcg tgtaaacggc aatttctgat
    20041 tgtgtttcga tagtgtgttg tgctgcataa agtcctgtcc agaaagaagt cggcctcgca
    20101 aaaatgaata aacccagttt ctcttgcgca acaggtggag aagtcgaata cgcagtatgt
    20161 aaaaaatgag gcaacagatt cactggggag gtcgcgagga ggcgcaattc tacaaaattg
    20221 cgcatttcac taccagtctg gagtcagccc ggatatgaac tgcaactatt gcaaataaag
    20281 aaattaagct ggaaggcatc gcgcaatgag gaagattgcc gggtgctgac agtaaaaagc
    20341 aatcgtagaa tcagcggcaa gccggaaagg ttccggtgag gcgcaatgtt gcgggggctt
    20401 tatccctggt ggcattggtt gctggagaga gaaaaccccc gcacgttgca ggtatgcacc
    20461 tgacaacacc acgggggcta atcttgactc tagaccactc aagaatagcc gcgaaacgtt
    20521 gtcattacaa cacaggcggc tatatgacgt tcgcagagct gggcatggcc ttctggcatg
    20581 atttagcggc tccggtcatt gctggcattc ttgccagtat gatcgtgaac tggctgaaca
    20641 agcggaagta acgtgtcatg cgggcgtcag gctgccgtaa tggcaatttg cgcccggacc
    20701 aggccgcagg ggggaaactc tgcggccttt ttcgttctta ctgcgggtaa ggcacccagt
    20761 cgccgccgtt caggcgaacg tacggtttat cctggtattg aataactact gcatttgagt
    20821 tctcggagac cggtgctgtt tgtggcaacc cactggtgag ttttttccag tcaacattgt
    20881 cttcggtgaa aatcttgcca tcgagaacgc gaaccaccag atcggagata gccaggaagc
    20941 tgctcggttg ttcgatgaca atcggtgccc cctgatgcgg tgccttcatg ccgaagaatt
    21001 tcaccccaac ggggacgtcg gtgatagacg ggctagggat atcacgtagg ccagatacct
    21061 gcattctgtc gcccttcagc gcgccgccgt gttccggcac cacgaccacc atcactttac
    21121 gacccgattt ctcaagttca gtaaagaagg cgtccagttc atcaaagaat ttctgcgccc
    21181 gcgctttgta atccgctgtt ttgctgaccc ccggataatg gttgccgtca tgcagtggaa
    21241 gcgtgttgta gaacgtggca ctacggctgt ttttatcttt ttcggtaacg tccagccagc
    21301 ggttaagcac agcggtatcg tcataaaccg gcgaaccatc aaagcccagc aaaataaccg
    21361 gcagatttgt ttgatccatc aattcgctct gcatgccgcc attttcgcga acttctttca
    21421 aaaaaccgcc gaactggccg ttatgtccca tcatcaggtg ctgggtaaag cccagtttcg
    21481 aaaggttatc aaacagatag cagtcgttat ttgccggttg atacagatta gtgtgcgaag
    21541 tctgcccgca gctggcgcgc agtaaacgga tcgccgccgg gccactgtag gaggtggcgg
    21601 agttaaagtt cttgaactca atatcgaaat gcgaccacag tggatgcgac atcaacccgg
    21661 cggcttctat atccgaccag gaaagcgaac agatgttaat caccagtagt tcaaatggct
    21721 gagcatcagc gggcagcgaa gacgggaagg tcgatttacg tttcgcctcc gcgttataga
    21781 aattattcag ccaggcgtta aggttcgccg ttgttggcgg tgcagtttgt gcgggcatat
    21841 cacccactac cggtgcgcca cccgtcgccg caacggttgc cgctgcgtta ccacccgtcg
    21901 ttgttacagt ggtcgtcggt tgtccggctg gccacaagaa gaaacttggt cccgccaggg
    21961 taagtacgtt cagccatagc agtatggcaa ccacaaaaac ggtaatgcga atccattgtg
    22021 acaggaataa ccaggccact aataaaacaa aaatggcccc aatcatctgc cagttaataa
    22081 agcgtgtgac atggtcgatt aaataatcgg tactgaaccc cgccacctgc gaaccctggc
    22141 tcattatgct ttccgggcca ggcaaccagg tgtcatgcca gaacaaagca aagccgatcg
    22201 gcagggcaat ccagtggcgc aagcgatgca ggctgtagcg cggaaggggc atcagcagaa
    22261 acgcggcaaa caccaaattg aggagcggat ggaagttaag atatcccgcc cacaacaggc
    22321 cgaacttaac cagaaaatag aagttccagc cggaaaggcc gcgccagtat tgccagaggg
    22381 aagaaggcat ggcggtattt tgcgtaaatt gagtcatttt ttggttgccc tggctttttc
    22441 cgtgcggcgt aacgtcccgg ccggtttaac ataacgaggt ttagcaaaga acaaacgtaa
    22501 ggtgtcgcga atgcgtcgca aagagtgccg cgccagatag cccagcggga aaaatatcag
    22561 tgcgcaaacg acaataattt caatgatatc gctgatggtc atcatgatga gcgctccaca
    22621 gcatcatcta acagtcgcat gggttctggt attcgtcgcc agtggcgacc atcgtgctcg
    22681 gcattgatga ccggtttaga accttgcgtt aaaggcagcg gcatgcccca ttgttctggg
    22741 gcaagcaagc gcatctgcac cagctcggca ctgatttgat catcttcaaa ccagaccata
    22801 cggtttgaga aaatgtcgcc agtaggcaat gggaaaatat gattcaacgc ggtatccaga
    22861 tcgttaatcc gacagaatga gagaaacagc accagccgat taccgccaat ggtcatgata
    22921 tcgccggtac ggttagggcg acacagcgtc agggcttgtt caacgcggat acccggtacc
    22981 ggacgtaggg caaccagaac gcctttaccg tgggcaggta atagagggtt attcatcatg
    23041 ttgttgacgg cattacagaa cacatcccac ttctggaaac cacgcagttt gagcggctgg
    23101 gtcattgaca gcaaggtagt gatatcttcc ggcacatagc gactaaactt ctgcccttgc
    23161 acgctttcga tcatcgtcag acaacgggag agtggcgcat tccacggaat aaccatattt
    23221 gcaccgcagg ccaataacaa acgttcatcg gtggcgcgca ggctagcggt attttcccgc
    23281 acgaggattt tcatcgcact accgcgctgg cgacgcaggg tatgaatgct gcgggccagt
    23341 ggctcgattt gcgcattttg ctgtaaagaa aagaccaccg tcgccgcctg agcggtacgg
    23401 gcttcattga acaggatttc gttattgttg aacagttgcc agtgttccga tagcggcggc
    23461 gcaccttcca gtacagcaac attactcaga atgcgttttt cgtcgctgcg tggttggatc
    23521 tccgcctctt cgctttgaac taatgtccag ataccatttt gttgctgaac gctaagctgc
    23581 tgacgggcgc tgaccccttt ttcgttgcac cagaaggcaa tatccagcaa atgttggtca
    23641 ccctgaaaac gcaaactggc aagaccaaaa agtgaacggt attcctcaag caacaatgaa
    23701 aattgtttat cgttattatt tccgggatta attaccaaaa gcgaacaatg gtttaacctg
    23761 ctccatttat tcattttatc caaccatgag cgaagccgct cggcaggaat gttttgccat
    23821 gcgttatttg cgcaaacaag aataaaaagg taattatggg gatcaataga acactgcaaa
    23881 tcacgggtca aatagtatag acctttttca tgatttagca ttgaaaataa ttttattttt
    23941 tccggccctt gagaatcatc taattgaaag attttcgccg gatcgctgtc catgctaatg
    24001 accgcgacgt gtgcggtttc agcctgggat gcaattgttt gattcgccag actgatagca
    24061 tcttcatggc gatcgacgtt aaaccaccag acgccgcctg ctggcatatg tcgcagctca
    24121 tcccataatg atgagatacc gatagagaat acagggtcca caatgtccct catgtcacca
    24181 ttttgtctga ttatcagttt actagcgaaa gctaagaaat aaacctacca ttgaaattaa
    24241 aacttatcag atttagcatg tgaatcaatt tagaaggtca caagacgtgt gattttagtc
    24301 ttttcgtttt taactttttc tgttgcgtaa cggaaagtca aaaagtgagc aaattcccgt
    24361 ctcgccgtaa acaataaacc ggcgaaatgc tcacggttag aattgtctca tgaacggtac
    24421 ggttatttca tagggatcaa gcaaaatgaa taacaatgaa ccagatactc tgcctgatcc
    24481 cgcgataggc tatatcttcc agaatgatat tgtggcgtta aagcaggcat tttcactgcc
    24541 tgatattgat tatgccgata tttcccaacg cgaacagttg gccgcggcat taaaacgctg
    24601 gccgttgctg gcagagtttg cgcaacaaaa gtaggggatt ggtgaatggc cgtactggga
    24661 ttgcaggggg tgcggggagg cgtggggaca acaaccatca ccgccgcatt agcctggtca
    24721 ttacaaatgt tgggagaaaa tgtcctggtg gtcgatgcct gcccggacaa cttgttgcgc
    24781 ctgtcattta atgttgattt tacccaccgt cagggctggg ccagagcgat gctggatggc
    24841 caggactgac gtgacgctgg gttgcgctac acctcgcagc tcgatttgct gccttttggt
    24901 cagttatcca ttgaagaaca agaaaatcca cagcactggc aaacccggct gagcgatatt
    24961 tgctccggct tacagcaact aaaagccagc gggcgttacc agtggatttt aatcgactta
    25021 ccgcgtgatg cctcgcagat aacccaccag ctgctgagtt tgtgcgatca ctcgctggca
    25081 atcgtcaatg tggatgccaa ctgccatatc cgactgcatc agcaagcgct gccggatggc
    25141 gcacatattt tgattaatga cttccgtatt ggcagtcagg ttcaggacga tatttaccag
    25201 ctttggttgc aaagccagcg ccgattactg ccgatgctca ttcatcgtga tgaagcgatg
    25261 gctgaatgcc tggcggctaa gcaaccagta ggtgaatatc gcagtgatgc gctggcggct
    25321 gaagagatac tgacgctggc gaactggtgc ctgttgaact actccgggct gaaaacgcca
    25381 gtcgggagtg catcatgagt atcctgaccc ggtggttgct tatcccgccg gtcaacgcgc
    25441 ggcttatcgg gcgttatcgc gattatcgtc gtcacggtgc gtcggctttc agcgcgacgc
    25501 tcggctgttt ctggatgatc ctggcctgga tttttattcc gctggagcac ccgcgctggc
    25561 agcgtattcg cgcagaacat aaaaacctgt atccgcatat caacgcctcg cgtccgcgtc
    25621 cgctggaccc ggtccgttat ctcattcaaa catgctggtt attgatcggt gcatcgcgca
    25681 aagaaacgcc gaaaccgcgc aggcgggcat tttcaggtct gcaaaatatt cgtggacgtt
    25741 accatcaatg gatgaacgag ctgcctgagc gcgttagcca taaaacacag catctggatg
    25801 agaaaaaaga gctcggtcat ttgagtgccg gggcgcggcg gttgatcctc ggtatcatcg
    25861 tcaccttctc gctgattctg gcgttaatct gcgttactca gccgtttaac ccgctggcgc
    25921 agtttatctt cctgatgctg ctgtgggggg tagcgctgat cgtacggcgg atgccggggc
    25981 gcttctcggc gctaatgttg attgtgctgt cgctgaccgt ttcttgccgt tatatctggt
    26041 ggcgttacac ctctacgctg aactgggacg atccggtcag cctggtgtgc gggcttattc
    26101 tgctcttcgc tgaaacgtac gcgtggattg tgctggtgct cggctacttc caggtagtat
    26161 ggccgctgaa tcgtcagccg gtgccattgc cgaaagatat gtcgctgtgg ccgtcggtgg
    26221 atatctttgt cccgacttac aacgaagatc tcaacgtggt gaaaaatacc atttacgcct
    26281 cgctgggtat cgactggccg aaagataagc tgaatatctg gatccttgat gacggcggca
    26341 gggaagagtt tcgccagttt gcgcaaaacg tgggggtgaa atatatcgcc cgcaccactc
    26401 atgaacatgc gaaagcaggc aacatcaaca atgcgctgaa atatgccaaa ggcgagttcg
    26461 tgtcgatttt cgactgcgac cacgtaccaa cgcgatcgtt cttgcaaatg accatgggct
    26521 ggttcctgaa agaaaaacag ctggcgatga tgcagacgcc gcaccacttc ttctcaccgg
    26581 acccgtttga acgcaacctg gggcgtttcc gtaaaacgcc gaacgaaggc acgctgttct
    26641 atggtctggt gcaggatggc aacgatatgt gggacgccac tttcttctgc ggttcctgtg
    26701 cggtgattcg tcgtaagccg ctggatgaaa ttggcggcat tgctgtcgaa accgtgactg
    26761 aagatgcgca tacttctctg cggttgcacc gtcgtggcta tacctccgcg tatatgcgta
    26821 ttccgcaggc ggcggggctg gcgaccgaaa gtctgtcggc gcatatcggt cagcgtattc
    26881 gctgggcgcg cgggatggta caaatcttcc gtctcgataa cccgctcacc ggtaaagggc
    26941 tgaagtttgc tcagcggcta tgttacgtca acgccatgtt ccacttcttg tcgggcattc
    27001 cacggctgat cttcctgact gcgccgctgg cgttcctgct gcttcatgcc tacatcatct
    27061 atgcgccagc gttgatgatc gccctattcg tgctgccgca tatgatccat gccagcctga
    27121 ccaactccaa gatccagggc aaatatcgcc actctttctg gagtgaaatc tacgaaacgg
    27181 tgctggcgtg gtatatcgca ccaccgacgc tggtggcgct gattaacccg cacaaaggca
    27241 aatttaacgt caccgccaaa ggtggactgg tggaagaaga gtacgtcgac tgggtgatct
    27301 cgcggcccta catcttcctt gtcctgctca acctggtggg cgttgcggta ggcatctggc
    27361 gctacttcta tggcccgcca accgagatgc tcaccgtggt cgtcagtatg gtgtgggtgt
    27421 tctacaacct gattgttctt ggcggcgcag ttgcggtatc ggtagaaagc aaacaggtac
    27481 gccgatcgca ccgcgtggag atgacgatgc ccgcggcaat tgcccgcgaa gatggtcacc
    27541 tcttctcgtg taccgttcag gatttctccg acggtggttt ggggatcaag atcaacggtc
    27601 aggcgcagat tctggaaggg cagaaagtga atctgttgct taaacgcggt cagcaggaat
    27661 acgtcttccc gacccaggtg gcgcgcgtga tgggtaatga agttgggctg aaattaatgc
    27721 cgctcaccac ccagcaacat atcgattttg tgcagtgtac gtttgcccgt gcggatacat
    27781 gggcgctctg gcaggacagc tacccggaag ataagccgct ggaaagtctg ctggatattc
    27841 tgaagctcgg cttccgtggc taccgccatc tggcggagtt tgcgccttct tcggtgaagg
    27901 gcatattccg tgtgctgact tctctggttt cctgggttgt atcgtttatt ccgcgccgcc
    27961 cggagcggag cgaaacggca caaccatcgg atcaggcttt ggctcaacaa tgatgataac
    28021 gcgatgaaaa gaaaactatt ctggatttgt gcagtggcta tggggatgag tgcgttcccc
    28081 tctttcatga cgcaggcgac gccagcaacg caaccactga tcaatgctga gccagctgta
    28141 gccgcccaga cggaacaaaa tccgcaggtg gggcaagtga tgccgggcgt gcagggcgct
    28201 gatgcgccag tcgtggcgca gaacggtcct tcgcgtgatg tgaagctgac ctttgcgcaa
    28261 attgcaccgc cgccgggcag catggtgcta cgtggcatta acccgaacgg cagcattgag
    28321 tttggtatgc gcagcgatga agtggtgacg aaggcgatgc tcaacctcga atacacccca
    28381 tcgccatcgt tactgcctgt ccagtcgcag ttaaaggttt atctcaatga tgaactgatg
    28441 ggcgtgctgc cagtgaccaa agaacagttg ggtaaaaaaa cgctggcgca aatgcccatt
    28501 aacccactgt ttattaccga cttcaaccgt gtacggctgg agtttgtcgg ccattatcag
    28561 gacgtgtgcg aaaacccggc cagcaccacg ctttggctgg atgttgggcg gagcagtgga
    28621 ctggatctga cctatcagac cctgaatgtg aagaatgacc tgtcacactt cccggtgcca
    28681 ttctttgacc cgcgcgataa ccgcaccaac accttgccga tggtctttgc gggtgcgccg
    28741 gatgttgggc tgcaacaagc ctctgccatt gtcgcctcgt ggtttggttc gcgttctggc
    28801 tggcgtgggc agaacttccc ggtactctat aaccaactgc cggatcgcaa tgccattgtc
    28861 tttgcaacca acgacaaacg gccggacttc ctgcgcgatc atccggcggt aaaagccccg
    28921 gtgattgaga tgattaacca tccgcagaat ccttacgtca aactgctggt ggtgtttggt
    28981 cgtgacgaca aagacctgtt gcaggcagcg aaaggtatcg ctcagggtaa cattctgttc
    29041 cgtggtgaaa gcgtggtagt gaatgaagtg aaaccgctgc taccgcgtaa gccgtacgat
    29101 gcgccgaact gggtacgtac cgatcgtccg gtcacatttg gcgaactgaa aacctatgaa
    29161 gaacagttac aatccagcgg tcttgagcca gcagcgatta acgtttcgct aaacctgccg
    29221 ccggatctct acctgatgcg cagtaccggc attgatatgg atattaatta ccgctacacc
    29281 atgccgccgg tgaaagacag ttcgcggatg gatatcagcc tgaataacca gttcctgcaa
    29341 tccttcaacc tgagcagcaa acaggaggcg aaccgcctgc tgctgcggat tccggtatta
    29401 caaggtttgc tggatggcaa aacagatgtc tctattccgg cgctgaaact gggcgcgacc
    29461 aaccagctgc gcttcgactt tgagtatatg aacccgatgc cgggcggttc ggtggataac
    29521 tgtattacct tccagccggt gcagaatcat gtggtgattg gtgacgactc caccatcgac
    29581 ttctcgaagt attaccactt catcccgatg ccggatctac gcgcctttgc taacgcgggc
    29641 ttcccattca gccggatggc ggatctgtcg caaaccatca ccgtgatgcc gaaagcgcct
    29701 aacgaagcac agatggaaac gttgctgaat actgttggtt ttatcggcgc acagacgggc
    29761 ttcccggcga ttaatctgac ggtgaccgat gatggcagca ccattcaggg caaagatgcc
    29821 gacatcatga tcatcggtgg tatcccggac aaactgaaag acgataagca gatcgaccta
    29881 ttggtgcagg cgaccgaaag ctgggtgaaa acaccgatgc gccagacccc gttccccggc
    29941 attgtgccgg acgagagcga tcgcgcggca gaaacccggt caacgctgac ctcttccggt
    30001 gcgatggcgg cggtgattgg cttccagtcg ccgtataacg accagcgcag cgtgattgcg
    30061 ctgttggcag atagcccacg cggttatgaa atgcttaacg atgcggtgaa cgatagcggc
    30121 aaacgcgcca ccatgttcgg ttcggtcgcg gtgatccgcg agtccggtat caacagccta
    30181 cgtgttggcg acgtttatta cgtaggtcat ctgccgtggt tcgagcgcgt gtggtatgcg
    30241 ctggcaaacc atccgattct gctggcggtg ctggcggcta tcagtgtgat attgctggca
    30301 tgggtactgt ggcgtctgct gcgaattatt agtcgtcgtc gtcttaaccc ggataacgag
    30361 taattgaaga tgaatgtgtt gcgtagtgga atcgtgacga tgctgctgct ggctgccttt
    30421 agtgttcagg cagcctgtac ctggcctgcc tgggagcagt ttaaaaagga ttacatcagt
    30481 caggaagggc gcgtcatcga ccccagcgac gcgcgcaaaa tcaccacctc cgaagggcaa
    30541 agttacggca tgttctctgc cctggcggct aacgaccgtg cagctttcga taatattctc
    30601 gactggacgc agaacaatct cgctcagggt tctttaaaag aacgtttgcc cgcctggctg
    30661 tggggcaaga aagagaacag taagtgggaa gtgctggaca gcaattcggc ctccgatggt
    30721 gatgtctgga tggcctggtc gttgctggag gcggggcgtt tgtggaaaga gcagcgttat
    30781 accgacatcg gcagcgcgtt gctaaaacgt atcgcgcggg aggaagtggt gacggtgcct
    30841 gggctgggtt ccatgttgtt accgggcaaa gtgggttttg ctgaggataa cagctggcgt
    30901 tttaacccca gctacctgcc gccgacgctg gcgcagtatt tcacccgctt tggcgcgccg
    30961 tggaccacgc tgcgcgaaac caatcaacgt ttattgctgg aaaccgcccc gaaaggtttt
    31021 tcgccagact gggtgcgcta tgagaaagac aaaggctggc agctaaaagc cgaaaaaaca
    31081 ttgatcagca gctacgacgc tatccgcgtt tacatgtggg taggcatgat gcctgacagc
    31141 gatccgcaaa aagcgcggat gctcaaccgg tttaaaccga tggcgacatt cactgagaaa
    31201 aacggttatc cgccggaaaa agtggatgtg gctacgggga aagcgcaggg taaaggacca
    31261 gtcggttttt ctgccgccat gctgcccttt ttacaaaacc gcgatgcgca ggccgttcag
    31321 cgccagcgcg tggccgataa ctttcccggc agcgatgcct attacaacta tgtgctgacc
    31381 ctgtttggat aaggctggga tcaacaccgt ttccgcttct cgacaaaagg tgagttatta
    31441 cctgactggg gccaggaatg cgcaaattca cactaaacat attcacgctt tccctcggtc
    31501 tggccgtcat gccgatggtc gaggcagcac caaccgctca gcaacagttg ctggagcaag
    31561 ttcggttagg cgaagcgacc catcgtgaag atctggtgca acagtcgtta tatcggctgg
    31621 aacttattga tccgaataac ccggacgtcg ttgccgcccg tttccgttct ttgttacgtc
    31681 agggcgatat tgatggcgcg caaaaacagc tcgatcggct gtcgcagtta gcgccgagtt
    31741 caaatgcgta taaatcgtcg cggactacga tgctactttc cacgccggat ggtcgtcagg
    31801 cactgcaaca ggcacgattg caggcgacga ccggtcatgc agaagaagct gtggcgagtt
    31861 acaacaaact gttcaacggt gcgccgccgg aaggtgacat tgctgtcgag tactggagta
    31921 cggtggcgaa aattccggct cgccgtggcg aagcgattaa tcagttaaaa cgcatcaatg
    31981 cggatgcacc gggcaatacg ggcctgcaaa acaatctggc gctattgctg tttagtagcg
    32041 atcgccgtga cgaaggtttt gccgtcctgg aacagatggc aaaatcgaac gccgggcgcg
    32101 aaggggcctc taaaatctgg tacgggcaga ttaaagacat gcccgtcagt gatgccagtg
    32161 tgtcggcgct gaaaaaatat ctctcgatct ttagtgatgg cgatagcgtg gcggctgcgc
    32221 aatcgcaact ggcagaacag caaaaacagc tggccgatcc tgctttccgc gctcgtgcgc
    32281 aaggtttagc ggcggtggac tctggtatgg cgggtaaagc cattcccgaa ctacaacagg
    32341 cggtgcgggc gaacccgaaa gacagtgaag ctctgggggc gctgggccag gcgtattctc
    32401 agaaaggcga tcgcgccaat gcagtggcga atctggaaaa agccctcgca ctggacccgc
    32461 acagcagcaa caacgacaaa tggaacagtc tgctgaaagt aaaccgctac tggctggcga
    32521 tccagcaggg cgatgctgcg ctgaaagcca ataatcctga ccgggcagaa cgcctgttcc
    32581 agcaggcgcg taatgtcgat aacaccgaca gttatgcagt gctggggctg ggcgatgtgg
    32641 cgatggcgcg aaaagattat cccgccgccg aacgttatta tcagcagacc ttgcgtatgg
    32701 acagcggcaa cactaacgcc gtgcgcgggc tggcaaatat ttaccgccag caatcgccag
    32761 aaaaagctga agcgtttatc gcctcgctct ctgccagtca gcggcgtagc attgatgata
    32821 tcgaacgcag cctgcaaaac gaccgtctgg cacagcaggc agaggcactg gaaaaccagg
    32881 gcaaatgggc gcaggcggca gcacttcagc ggcaacgact ggcgctggac cccggcagcg
    32941 tatggattac ttaccgactt tcgcaggatc tctggcaggc cggacaacgc agccaggccg
    33001 atacgttaat gcgcaatctg gcgcagcaga agtcgaacga cccggagcag gtttacgctt
    33061 acgggctgta cctctctggt catgaccagg acagagcggc gctggcgcat atcaacagcc
    33121 tgccgcgtgc gcagtggaac agcaatattc aggagctggt taatcgactg caaagcgatc
    33181 aggtgctgga aaccgctaac cgcctgcgag aaagcggcaa agaggcagaa gcggaagcga
    33241 tgctgcgcca gcaaccacct tccacgcgta ttgacctcac gctggctgac tgggcgcaac
    33301 aacgacgtga ttacaccgcc gcccgcgctg catatcagaa tgtcctgacg cgggagccag
    33361 ctaacgccga cgccattctt ggtctgacgg aagtggatat tgctgccggt gacaaagcgg
    33421 cggcacgtag ccagctggcg aaactgcccg ctaccgataa cgcctcgctg aacacacagc
    33481 ggcgcgtggc gctggcacag gcgcagcttg gcgataccgc agcagcgcag cggacgttta
    33541 ataagttgat cccgcaggca aaatctcagc caccgtcgat ggaaagcgcg atggtgctgc
    33601 gtgatggtgc gaagtttgaa gcgcaggcgg gcgatccaac gcaggcgctg gaaacctaca
    33661 aagacgccat ggtcgcatcc ggtgtgacta cgacgcgtcc gcaggataac gacaccttta
    33721 cccgactgac ccgtaacgac gagaaagatg actggctgaa acgtggcgtg cgcagcgatg
    33781 cggcggacct ctatcgccag caggatctta acgtcaccct tgagcacgat tactggggtt
    33841 cgagcggcac cggtggttac tccgatctga aagcgcacac taccatgttg caggtggatg
    33901 cgccgtattc tgacgggcgg atgttctttc gcagtgattt cgtcaatatg aacgtcggca
    33961 gtttctccac taatgccgat ggcaaatggg atgacaactg gggcacctgt acattacagg
    34021 actgtagcgg caaccgcagc cagtcggatt ccggtgccag cgtggcggtc ggctggcgaa
    34081 atgacgtctg gagctgggat atcggtacca cgccgatggg cttcaacgtg gtggatgtgg
    34141 tcggcggcat cagttacagc gatgatatcg ggccgctggg ttacaccgtt aacgcccacc
    34201 gtcggcccat ctccagttct ttgctggcct ttggtgggca aaaagactcc ccgagcaata
    34261 ccgggaaaaa atggggtggc gtacgtgccg acggtgtggg gctaagtctg agctacgata
    34321 aaggtgaagc aaacggcgtc tgggcatcgc ttagtggcga ccagttaacc ggtaaaaatg
    34381 tcgaagataa ctggcgcgtg cgctggatga cgggctatta ctataaggtc attaaccaga
    34441 acaatcgccg cgtcacaatc ggcctgaaca acatgatctg gcattacgac aaagatctga
    34501 gtggctactc actcggtcag ggcggttact acagtccgca ggaatacctg tcgtttgcca
    34561 taccggtgat gtggcgggag cgcacggaaa actggtcgtg ggagctgggt gcgtctggct
    34621 cgtggtcgca ttcacgcacc aaaaccatgc cgcgttatcc gctgatgaat ctgatcccga
    34681 ccgactggca ggaagaagct gcgcggcaat ccaacgatgg cggcagcagt cagggcttcg
    34741 gctacacggc gcgggcatta cttgaacgac gtgttacttc caactggttt gttggcacgg
    34801 caattgatat ccagcaggcg aaagattacg cacccagcca tttcctgctc tacgtacgtt
    34861 attccgccgc cggatggcag ggtgacatgg atttaccgcc gcagccgctg ataccttacg
    34921 ccgactggta agttttcaga tagcgcctct cttaatgccg ctgcgatcgg gtatactcgg
    34981 gcggcaatct gggatttccg gggggagaca atttgcgcgt aagtcgctcg ttaacaatca
    35041 agcagatggc aatggtggca gccgttgtcc tggtgttcgt ttttattttt tgcaccgttt
    35101 tgctgttcca tctggtccag cagaatcgct ataacacggc tacgcaactg gaaagcattg
    35161 ctcgctctgt ccgcgaaccc ttatcttcag ctattttgaa aggcgatatt cccgaagcgg
    35221 aagctattct tgccagcatt aaaccggcag gcgtggtcag ccgtgccgat gtagtgctgc
    35281 ctaaccagtt ccaggcgctg cgtaaaagtt ttattccaga gcgcccggtg ccggtaatgg
    35341 ttactcgcct gtttgagcta ccggttcaaa tctcgctggg cgtttactcg ctcgaacgtc
    35401 cggcaaaccc gcagccaatt gcctatctgg tactacaggc ggattccttc cgtatgtata
    35461 agttcgtgat gagcaccctc tcaacgttag tgaccattta cttacttttg tcgcttatcc
    35521 tgaccgtcgc catcagctgg tgcattaacc gcctgatttt gcatccgtta cgcaatattg
    35581 ctcgcgaact taacgccatc ccagccaagg agcttgttgg tcaccaactg gcattaccgc
    35641 gtctgcatca ggacgatgaa atcggtatgt tggtgcgcag ttacaacctc aaccagcaat
    35701 tgctgcagcg ccattatgaa gaacagaacg aaaatgcgat gcgcttcccg gtgtcggatt
    35761 tgccgaacaa agccttgctg atggagatgc tggagcaggt tgtcgcgcgt aaacaaacca
    35821 ccgcgctgat gatcatcacc tgtgaaaccc tgcgtgatac tgcgggcgtg ctgaaagagg
    35881 cgcaacgaga aattctgctg ctgacgctgg tggaaaaact caaatcggta ctgtcgccac
    35941 gtatgatcct cgcgcagatt agcggttatg actttgctgt cattgccaac ggtgtacagg
    36001 aaccgtggca cgcaatcacc ttaggtcagc aagtgctcac tatcatgagc gagcgcctgc
    36061 cgattgaacg tattcaactc cgtccgcact gtagcattgg cgtggcgatg ttctacggcg
    36121 atctcaccgc cgaacagctt tacagtcgcg ctatttctgc ggcatttacc gctcgccata
    36181 aaggcaagaa tcagattcag ttctttgatc cgcagcagat ggaagccgcc cagaagcggt
    36241 tgacggaaga gagcgatatc cttaatgcac tggaaaatca tcagtttgct atttggttac
    36301 agccacaggt cgagatgacc agcggtaaac tggtcagtgc ggaagtgtta ctgcgtatcc
    36361 agcaaccgga tggcagttgg gacctgccgg atggcttaat cgatcgcatt gagtgctgtg
    36421 ggctgatggt taccgtcggt cactgggtgc tggaagagtc ctgtcgattg cttgcagcct
    36481 ggcaagagcg cggcattatg ctgcccttgt cggtaaacct ctctgcgctg caactgatgc
    36541 acccgaatat ggtggcggat atgctggaac tgttaacccg ctatcgcatt cagccgggaa
    36601 cactgattct ggaagtgaca gaaagccgac gtattgacga ccctcatgct gcggtggcaa
    36661 tcctccgtcc gctgcgcaat gccggagttc gggtggcgct ggatgatttc ggcatgggct
    36721 acgcagggct gcgtcagctg cagcatatga aatcgttgcc aatcgacgta ctgaaaatcg
    36781 acaaaatgtt tgttgaaggc ttgccgggag atagcagcat gattgctgca attatcatgc
    36841 tggcgcagag cctgaactta caaatgattg ccgaaggcgt ggagactgaa gcacaacgcg
    36901 actggctggc aaaagcgggc gttggtattg cccagggctt cctttttgct cgcccactcc
    36961 ctattgaaat cttcgaagag agttacctgg aagaaaagta gctaccccaa actgattaca
    37021 aaactttaaa aagtgctggt ttgtgcgagc cagctcaaac tttttaacct ttttgtttca
    37081 attatgatcc aggtacattt ctgtgatgtt gtctgggtgt tattttaagg ccgcaggtac
    37141 cccataacct tacaagacct gtggttttac taaaggacac cctatgaaaa cctctctgtt
    37201 taaaagcctt tactttcagg tcctgacagc gatagccatt ggtattctcc ttggccattt
    37261 ctatcctgaa ataggcgagc aaatgaaacc gcttggcgac ggcttcgtta agctcattaa
    37321 gatgatcatc gctcctgtca tcttttgtac cgtcgtaacg ggcattgcgg gcatggaaag
    37381 catgaaggcg gtcggtcgta ccggcgcagt cgcactgctt tactttgaaa ttgtcagtac
    37441 catcgcgctg attattggtc ttatcatcgt taacgtcgtg cagcctggtg ccggaatgaa
    37501 cgtcgatccg gcaacgcttg atgcgaaagc ggtagcggtt tacgccgatc aggcgaaaga
    37561 ccagggcatt gtcgccttca ttatggatgt catcccggcg agcgtcattg gcgcatttgc
    37621 cagcggtaac attctgcagg tgctgctgtt tgccgtactg tttggttttg cgctccaccg
    37681 tctgggcagc aaaggccaac tgatttttaa cgtcatcgaa agtttctcgc aggtcatctt
    37741 cggcatcatc aatatgatca tgcgtctggc acctattggt gcgttcgggg caatggcgtt
    37801 taccatcggt aaatacggcg tcggcacact ggtgcaactg gggcagctga ttatctgttt
    37861 ctacattacc tgtatcctgt ttgtggtgct ggtattgggt tcaatcgcta aagcgactgg
    37921 tttcagtatc ttcaaattta tccgctacat ccgtgaagaa ctgctgattg tactggggac
    37981 ttcatcttcc gagtcggcgc tgccgcgtat gctcgacaag atggagaaac tcggctgccg
    38041 taaatcggtg gtggggctgg tcatcccgac aggctactcg tttaaccttg atggcacatc
    38101 gatatacctg acaatggcgg cggtgtttat cgcccaggcc actaacagtc agatggatat
    38161 cgtccaccaa atcacgctgt taatcgtgtt gctgctttct tctaaagggg cggcaggggt
    38221 aacgggtagt ggctttatcg tgctggcggc gacgctctct gcggtgggcc atttgccggt
    38281 agcgggtctg gcgctgatcc tcggtatcga ccgctttatg tcagaagctc gtgcgctgac
    38341 taacctggtc ggtaacggcg tagcgaccat tgtcgttgct aagtgggtga aagaactgga
    38401 ccacaaaaaa ctggacgatg tgctgaataa tcgtgcgccg gatggcaaaa cgcacgaatt
    38461 atcctcttaa tctcatcact tatgcccgca ctcccttccc cgagtgcggg tgtttgcgca
    38521 taattgaccc ctgtgcctga acttaccacc tgggtgagtt caggtttatt tcacttcttc
    38581 cgtgacattt tcatgttctt gcggtctaac acgaagtgtt tttaacgtca tttagactga
    38641 ccgacaacgg gcagtttttt tattaccagg atagttgatc aggggttcac atgcagggca
    38701 caaaaattcg acttttagcg ggcggtttgc tgatgatggc cactgctggc tatgtgcagg
    38761 cagatgcgct ccagcctgat ccagcatggc aacaggggac gctttccaac ggtttacagt
    38821 ggcaagtgct gaccaccccc cagcgtccca gcgatcgtgt tgaaattcgc ctgctggtta
    38881 ataccggttc gctcgccgaa agtacacaac agagcggtta cagtcacgcc atccctcgta
    38941 ttgcgctaac gcaaagcggt ggccttgacg cagcacaggc gcgttcattg tggcagcagg
    39001 ggatcgaccc taaacgcccg atgccgccgg taattgtctc ttatgacacc acgctgttta
    39061 atctgagttt gcccaataac cgtaacgatt tgctgaaaga agcgctctct tatctggcaa
    39121 atgccactgg caaattgacc atcacaccag aaaccatcaa ccacgcgctg caaagtcagg
    39181 acatggtggc aacctggcct gccgatacta aagagggctg gtggcgctat cgtctgaaag
    39241 ggtcaacctt gttaggtcac gatcctgccg atccgctgaa acaacccgtt gaagcggaaa
    39301 aaattaaaga tttctatcag aaatggtaca ccccggatgc aatgacgcta ctggtggtgg
    39361 gaaacgtgga tgcgcgctcg gttgtcgacc aaataaacaa aacgtttggc gaactgaaag
    39421 gcaaacgtga aacgccagct ccggtgccga cgctttctcc gctgcgtgcg gaagcggtga
    39481 gtattatgac tgacgcggtg cgtcaggacc ggttatctat catgtgggat acgccgtggc
    39541 agccgattcg tgaatcagcc gcactgctgc gctactggcg tgcggacctg gcccgcgagg
    39601 cgctgttctg gcatgttcag caagcgttaa gtgccagtaa cagcaaagac atcggtcttg
    39661 gatttgactg ccgtgtgctg tatctgcgtg cgcagtgtgc catcaacatc gaatcaccaa
    39721 acgacaagct gaacagcaac cttaatctgg tggcgcgtga actggcgaag gttcgcgata
    39781 aaggtctgcc ggaagaagag ttcaatgcgt tagtggcgca aaagaaactg gagctgcaga
    39841 aactgtttgc cgcctatgca cgagctgata ccgatattct gatgggtcag cggatgcgtt
    39901 cgttgcaaaa tcaggttgtc gatatcgcgc cggagcaata tcagaaactg cggcaggatt
    39961 tccttaatag cctgacggta gagatgttaa atcaggatct gcgtcaacag ttgtcgaatg
    40021 atatggcgtt aatactgctg cagccgaaag gcgagccgga atttaacatg aaagcgttgc
    40081 aggcggtctg ggatcaaatc atggccccat ctaccgccgc tgcgaccacc tctgtcgcca
    40141 cggatgacgt acatcctgaa gtgacggata ttccacctgc acagtaatgc ctgatggtga
    40201 tgagttagca caaccatcag gtatttatgg atgagctgga tagaggggta acactttatc
    40261 cagccttttg catatgctgc gtttacgctg gcatcgcctc acgcgggata atcgcgccgc
    40321 gatactgaat aacggtactt gcggtcaggt gcccacgttt cgccgcgtct tccgcgctgc
    40381 cgcctgtcag acgtaccgcc agataaccgg cactgaaaga gtcgccagct gcggtggtat
    40441 cgatcacttt ttctttcggc agtttcaccg ccggaacatc cactaaccct tcgccagcaa
    40501 tggacaccag gcaagaatcc gccccgcgtt tcaccaccac ttctttcacg cccgcgttat
    40561 gggtgcgcgc aatgacgtct tccaccggct gttgacccca cagcgcgtct tcgtcgtcca
    40621 gcgtcaggaa ggcgatatcc gtgcattcca gcatttgttg gtacacctgc tgtgtctctt
    40681 ctttgctggc ccacaggcgc ggacgatagt tattgtcgaa aatcactttt ccgccgttgg
    40741 cgcggcattc gcgcagcagg gaaagcagct tttcgcggct ggtcgggctt aagatcgcca
    40801 ggctaatccc gctcaggtag agataatcga aattcgccag ctcttcgcaa atcgccgcag
    40861 actgctcact ctccagccag aatttggcgg cggcttcgtt ccgccagtag tagaacgtac
    40921 gctcgccggt gctgtcggtt tcaatgtagt aaaggcccgg cagacggttt tccatccgtt
    40981 gggtcaggga agtatcaacg ttctcgccgt gccaggcgtc cagcatctgc tggctaaaac
    41041 tgtccgttcc cagcgccgtt acgtaatgaa cggttaatgc cgcaggatcg acctgacggg
    41101 cgatatagac ggaagtgttc agggtatcgc cgccgaaacc gcgcttaacg tccgcgcctt
    41161 tctcggaaag ctcaatcatg cattcgccaa tcacggcaat ctttttggac atagtcgtga
    41221 acctgatctg taaaaaatta gcgttagttt gcgctgtggt ggtttgctgg tcaaccatat
    41281 taaaacagtg ttccattatt tttttgagcc agaacgtatt cctgaaagat tccgttgtgg
    41341 agtgaggaaa tttaccccgg ccaggcggta aagttctgcc cttacgcgcc gataatcttt
    41401 gtcgagtccg ggcagcatca cttttaaaca caggacatct ttgatgataa ggcaggttat
    41461 ccagcgaata agcaaccctg aagcaagcat cgagagcttg caggaacggc gtttttggtt
    41521 gcagtgtgag cgtgcttaca cctggcagcc gatctatcaa acatgcgggc ggttaatggc
    41581 cgtggagcta ttaacggtgg tcacgcatcc cttgaaccct tcgcaacgcc tgccgccgga
    41641 tcgctatttt actgaaatca ccgtcagcca tcggatggag gttgtgaaag agcagattga
    41701 tttgctggcg caaaaagccg acttctttat agagcacggc ctgctggcat cggtcaatat
    41761 tgatggccct acgctcatcg ccctgcgtca gcaaccaaaa atcctgcgcc agattgagcg
    41821 tcttccctgg ctgcgtttcg aactggtgga gcatatccgt ctgccgaaag attcaacctt
    41881 tgcctcgatg tgtgaatttg gcccgctgtg gctggatgat tttggtaccg ggatggcaaa
    41941 tttctctgcg ctaagtgaag tgcgttatga ctacatcaaa atcgcgcgag aactgtttgt
    42001 gatgctgcgt cagtcgccgg aaggacgcac actcttttct cagcttttac atctaatgaa
    42061 tcgctattgt cgcggggtga ttgtcgaggg cgtagaaacg ccggaagagt ggcgtgatgt
    42121 tcagaactcg cccgcattcg ccgcacaagg ctggtttctt tcacgcccgg caccgataga
    42181 aacgctgaat acggcggttc tggcgctata agctgcctca ttttccgcct ggctggacta
    42241 tctttaggac tggcacagga agaatatgag gaagcgaacg atgagcaagg caggcaaaat
    42301 aaccgctgcg atttcagggg ctttcttgtt gttgattgtc gtggcgatca ttttgattgc
    42361 aacttttgac tggaatcgac tcaaaccgac tatcaaccag aaagtctctg cggagttgaa
    42421 tcgtccgttc gctatccgtg gcgatctggg cgtggtgtgg gagcggcaaa aacaagaaac
    42481 tggctggcgc agctgggtgc cgtggcccca tgtacacgcg gaagacatca ttcttggcaa
    42541 tccaccggat attcccgaag tcacgatggt gcatttgcca cgcgtagagg caacgctggc
    42601 cccgctggcg ctgctgacca aaacggtctg gctgccgtgg atcaagctcg gaaagcccga
    42661 cgcgcgcctg attcgcctct ctgaaaagaa caataactgg acgtttaatc ttgccaacga
    42721 tgataacaaa gacgcgaatg caaagccgtc ggcatggtcg tttcggctgg ataatattct
    42781 tttcgatcaa gggcggatcg ccattgatga caaagtaagc aaagcggatc tggagatttt
    42841 tgttgatccc ttaggcaagc cgctgccgtt cagcgaagtt actggatcga aaggtaaagc
    42901 ggataaagaa aaggtgggcg attacgtttt tggcctgaag gcgcagggac gatataacgg
    42961 tgaaccgctc acgggtacgg gaaaaatagg cggtatgctg gcgctgcgtg gcgaagggac
    43021 gccgtttccg gtacaggctg atttccgctc tggtaacacc cgtgttgctt ttgatggcgt
    43081 cgtgaatgac ccaatgaaga tgggcggtgt cgatttacgg cttaaatttt ctggcgattc
    43141 actgggtgat ctctatgaac tgacgggcgt tctgctgccc gataccccgc cgtttgaaac
    43201 ggatggtcgg ctggtagcga aaatcgacac tgaaaaatcg tcggtctttg attatcgcgg
    43261 ttttaatggg cgaattggtg atagcgatat ccacggttct ctggtctaca ccaccggaaa
    43321 gccacgacca aaactggaag gtgatgtcga gtcgcggcaa ttgcggctgg cggacctggg
    43381 accgttgatt ggcgttgatt ccgggaaagg ggcagaaaag tcgaaacggt ctgaacagaa
    43441 gaagggcgaa aaaagcgttc agcctgcggg caaagtgctg ccttatgacc gcttcgaaac
    43501 cgataaatgg gacgttatgg atggcgatgt tcgcttcaaa gggcggcgca ttgagcatgg
    43561 cagtagcctg ccgattagcg atctttctac tcatatcatc ctcaaaaatg ctgacctgcg
    43621 cctgcaaccg ctgaaatttg gcatggcggg cggcagcatt gcggcgaata ttcatctgga
    43681 aggcgataaa aagccgatgc aggggcgggc agatattcag gctcgtcgac tgaaactgaa
    43741 agaactgatg cccgatgtgg aactgatgca gaagacgctg ggggaaatga acggtgacgc
    43801 ggaactacgc ggtagcggta actcggtggc ggcactttta ggcaacagta acggcaacct
    43861 gaaactgttg atgaatgacg ggctggtgag ccgcaacctg atggagattg ttgggctgaa
    43921 tgtcggcaac tacattgtcg gtgcgatatt tggtgatgat gaggtgcggg tgaactgcgc
    43981 ggcggcgaat ctgaatattg ccaacggcgt ggcgcgcccg cagatttttg ctttcgatac
    44041 tgagaacgcg ttgattaatg ttaccggcac ggcaagtttt gcttcggaac agctggattt
    44101 gactattgat ccggagagta aaggaattcg gattatcaca ctgcgttcgc cgctgtatgt
    44161 gcgggggacg tttaaaaatc cgcaggctgg ggtgaaagcc ggaccgctga ttgcccgtgg
    44221 tgctgttgct gcggcactgg caacgctggt aacaccggcg gcggcgttac tggcactgat
    44281 ctcaccttcc gaaggggagg ctaatcagtg tcggacgatt ttgtcgcaga tgaagaagtg
    44341 atgataattg ccggatgtct gacatccggc aattaaacag atttagattg ttggcaaagt
    44401 gtgctttgtt catgccggat gcggcgtgaa cgccttatcc ggcctacaaa tccttgcgaa
    44461 ttcaatatat tgtatggaaa ttcaggcctg ataagcgtag cgcatcaggc ttttcactct
    44521 tattacaacg actgatgtcg cgtctcatgg gtcagcagca gggcgattaa cgtcaagcca
    44581 gccatcgccg ccagatataa ccccaccgca cctagcccgt agttagtctg caaccaggct
    44641 gcgatatatg gcgcaacgga agccccgaga atcgacgcta cgttgtaaga gaacgatgct
    44701 ccggtgtaac gcacttctgt cggaaacagc tctggtaaca gcgcacccat tggcccgaag
    44761 gtcagaccca tcagacttaa ccccagcagc aggaaggcaa aaaccagaat cgggttgcca
    44821 gaaccgagca gtgggttaaa ggcgaacagc gcgaacagga tgatcagcgt ggtgatgatt
    44881 accatgcttt tacggcgacc aaaggcatca gccagtaatc cagcgactgg caccatcacg
    44941 ccaaaaccaa taactgccat catcaacatc cacaacactt cgttacgcgg caggccaagc
    45001 ccaactggcg cggcggcggt actaaaggtc atagagtaga ccgtcatgat gtaaaacagc
    45061 gtataggttg ccagcataat gaacgtaccc agtacggtta cgcgaacatg tttggtcagc
    45121 agcgtaccca gcgggatctt cacctgtttt ttcgctttag cgactttctc aaacaccggc
    45181 gactcatgca gcgacacgcg aacatacagg ccgataatga ccagcaccgc cgagaagata
    45241 aatggcacac gccagcccca gctcataaac tgctcgtcgg tcagtagcca ggaaagcagc
    45301 aagaaagtgc cattggcaaa gaagaagcca atcggtgcgc ccagctgcgg aaaggagcca
    45361 tacagtgcac gtttgcgcgg tggggcgttt tcagtcgcca gcagcgccgc gccgccccat
    45421 tcaccgccta agcccagacc ctgaccaaat cgagccagcg ccagcagcag cggggcgaaa
    45481 ataccaatcg tggcatagcc cggcagcaga ccaatcacca cggtcgaaat ccccatcgtt
    45541 agcaacgagg cgaccagcgt cgctttacgc ccaacgcgat cgccaaaatg accaaaaacg
    45601 gcagagccaa tggggcgcgc gacgaaggcg atggcgaagg tggcgagcga ctgtagcgtt
    45661 gctgccgtag gatcgccctg cgggaagaag atatgcggaa acacaataac ggccgcagtg
    45721 gcgtaaatgt aaaagtcgaa gaactcaatg gctgtgccaa tgagagaggc gacaaggact
    45781 ttattacgcg agttgatcgg cgtgtattct tgctcgtggt cgagtgttgt ggctgttgct
    45841 tgcataatct tttcttattt tttggctaac gaatagccat attacgcaca gcaaaagtga
    45901 tatttcaatg tgtaacaaat cgcggaaatg gtcaaaaatc aggcaaaaag gggataatgt
    45961 ttaggccagt gatttttctt ctatgaaatg cttcacataa ttttataaat agtggataaa
    46021 actggtttca ggttaaataa aagttaccaa ctggatttat atgctggggt tatgagttgg
    46081 aatgaaattg tttgctccca aatagatggc tgaagaggct ctggggacga gtttcaagag
    46141 gttatgtgcg cattatagcc ggatgcgatg ctggcgcatc ttatccggcc tacggggagc
    46201 caggccgaat aaaatcgtat gccggataag gcgtttacgc cgcatccggc ctattttaag
    46261 gctgcgtttt ccccggcatt cgcgggtcgt ctttatattc ggcggtggca atccacgccg
    46321 cgcaaaacag cgtcaaacgg gcgaagaagt agaaaaatgc catcagcccc agcacggaac
    46381 caaatgctgc gccagagggg gatttcatca acgatggcag ggtgtaggtc atcacgattt
    46441 taatcacttc aaaaccaata gcagccagaa atgttccgcg aatcagggct tttttgcgcg
    46501 gacggtggcg cggcaaccgc cagaagatcc agaagaaaag cagatagttg gcgaagatgg
    46561 aaatcgccag gccaatcaat cgccacgtcg gtttcagcca ctcaatgctg ttcaggtgca
    46621 gggcgctaat aatcatttgc tgcgccgaac cggcaaccga ggtgatcgaa agcgtcacaa
    46681 tcagcgcaat caacaaacca atcagcgaaa taaaatctcg cagatatttt acccagaact
    46741 tctcctgatc ttgcggcgag cgttcccaga catcgcgcga ctgggcacga atcgcttcac
    46801 gcaggttacc catccagttg atgccggaat aaagtgccac cgccaggccg acaagcccta
    46861 cagtcgtacg ctgctgaacg gcggtgttga tggtgttttt caacgtggcg gctagcgtcg
    46921 gatcgctgat gttttgcaga attttgtcga agatatcctg tagcaacatc ggatgggagg
    46981 ccagcacaaa gccccctgcg gcaaacgaca ccatcaaaat tggtatcatc gacaaaaatg
    47041 agaaataggt gatagccgca ccaaactggt tacccagccg atcgttaaag cgttctgtcg
    47101 cgcgaatcag gtgcgcaata accggttggc gttggacttt ttcggcagtg gtggtgacgg
    47161 tttccagcgc ctggctaact ttgctgcctt tctcgctatt atccaacggc ttaatcggct
    47221 cgtgctccag atcctggatg ggacgtttga tctcgttttc ctgcgtcatc cgctcttttg
    47281 tccttctgtc gtggtcattc ttaaaaagta tagtcggtca gtccaggtac tctttcatta
    47341 cgccagccag ccactgcata aacaggttta cacgccggga aagctcccga cgctgcggat
    47401 aaaccagcga aagggagagc ggctcggcac ggtagccagg taatacttca ataagccgcc
    47461 cggcacgcag ggcttcgcgc acggcaatgc gcgggatctg aataatcccc agaccggcaa
    47521 gaccggcggt gagatagttt tcgctactgt ttaccgtcaa catgccgcca gacttaaacc
    47581 actggacgcc attaacgctg gcaacctcaa aacctaacgg atgtacaccc aggtgcggtg
    47641 tataacgcac tattgcgtgt gaagtcagat catcggggct ttgcggataa ccaaagcgcg
    47701 tcagatagtg cggactggca cagttgacca tggtcagttt gccgagggga cgggcgataa
    47761 cgccatcttc cggtaacgcg ccagtgcgta tcacgcaatc aaaaccatca tgaagaatat
    47821 ctaccggacg gtcatggcta ctcagttcca gctcaattcc cggatgcaga tagagaaatt
    47881 ccgacaggcg cggcagtaac aggcttttcg cgattcctgg cgggatgtcg atgcgtaatt
    47941 taccgctgat actggtggca tcctgttgaa acagaccgtc cagttcgctg agattactca
    48001 acacatcttt tgctcgttga taataggtca tgccttctgg cgtgagtttg acccgtcgcg
    48061 tggtgcgctg gagaagctgg gtgccaagtt gatgttccag tgcctgtatc tggcgcgaaa
    48121 cacttccctt tggcaaagca aagaaatccg ctgcgcggga aaaactttcc agctccgcga
    48181 ctttgatgaa caactgcatt gcgtgaattt tatccatttc tttgaccgat tgttgttcac
    48241 agcgaaacag taacgcgcat atcgcattgt ttattgtttt ttctaacatc taatgccggg
    48301 tttcacaatg ttgtcatgcc gaatgtggcg atttctcagc aggaaaaggg cggaatagct
    48361 ttctgagaaa ggtgaatccc cttaaacaga gcgtattttt cagcgattcc ctttaaagtg
    48421 aacagaggac gtgttggcta tttgtgctta tttttgtctc cttgccgttt gttattttgg
    48481 cttgtggtcg cggaatttca tttttaattg catgcgtact aaccaccaat ataaggaaat
    48541 cctcaaaatt gttttaaata gtgccctcga catgtaattt caggcgttta gctgtaacta
    48601 tttatatcgg taactatttt ctacacgtca tctctgtaga atggccaccg ccaaatggcg
    48661 aattcttatt ttttctcgcg ggtaataccc ttccactact taagtctttt taacgtattc
    48721 aggtggagat tcagttatgc aaatagtcat gtttgacagg cagtcaatat ttattcatgg
    48781 aatgaaaatc agtttacagc agcgtattcc aggagtgagt attcaggg
//
LOCUS       DAPOAV010000026        48486 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.026, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000026 DAPOAV010000000
VERSION     DAPOAV010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 48486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48486
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.026"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..267)
                     /locus_tag="RN951_001745"
     CDS             complement(<1..267)
                     /locus_tag="RN951_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526754.1"
                     /translation="MSQNDIIIRTHYKSPHRLHIDSDIPTPSSEPINQFARQLITLLD
                     TSDLSSMLSYCVTQEFTANCRKISQNCYSTALFTINFATSPIHTE"
     gene            791..2719
                     /gene="thrS"
                     /locus_tag="RN951_001746"
     CDS             791..2719
                     /gene="thrS"
                     /locus_tag="RN951_001746"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006894721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HDX2526755.1"
                     /translation="MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGEL
                     VDACDLIENDAQLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGF
                     YYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSIL
                     DENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRI
                     YGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRE
                     LEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNC
                     PGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQ
                     IRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNI
                     PFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPV
                     MIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAG
                     IRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEV
                     IEKLQQEIRSRSLKQLEE"
     gene            2723..3265
                     /gene="infC"
                     /locus_tag="RN951_001747"
     CDS             2723..3265
                     /gene="infC"
                     /locus_tag="RN951_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HDX2526756.1"
                     /translation="MKGGKRVQTARPNRINGEIRAQEVRLTGLEGEQLGIVSLREALE
                     KAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGT
                     DEGDYQVKLRSLIRFLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLQELAVVES
                     FPTKIEGRQMIMVLAPKKKQ"
     gene            3362..3559
                     /gene="rpmI"
                     /locus_tag="RN951_001748"
     CDS             3362..3559
                     /gene="rpmI"
                     /locus_tag="RN951_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006708231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HDX2526757.1"
                     /translation="MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHL
                     RPKAMVSKGDLGLVIACLPYA"
     gene            3612..3968
                     /gene="rplT"
                     /locus_tag="RN951_001749"
     CDS             3612..3968
                     /gene="rplT"
                     /locus_tag="RN951_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HDX2526758.1"
                     /translation="MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQ
                     YAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFD
                     KVAFTALVEKAKAALA"
     misc_feature    4085..4209
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01859"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Phe leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF01859"
     gene            4091..4135
                     /gene="pheM"
                     /locus_tag="RN951_001750"
     CDS             4091..4135
                     /gene="pheM"
                     /locus_tag="RN951_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pheST operon leader peptide PheM"
                     /protein_id="HDX2526759.1"
                     /translation="MNAAIFRFFFYFST"
     gene            4419..5402
                     /gene="pheS"
                     /locus_tag="RN951_001751"
     CDS             4419..5402
                     /gene="pheS"
                     /locus_tag="RN951_001751"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004851795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HDX2526760.1"
                     /translation="MSHLAELVASAKAAISQASDVAALDNVRVEYLGKKGHLTLQMTT
                     LRELPPEERPAAGAVINEAKEQVQQALNARKAELESAALNARLAAETIDVSLPGRRIE
                     NGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWF
                     DTTRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNI
                     SFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVH
                     PNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK"
     gene            5417..7804
                     /gene="pheT"
                     /locus_tag="RN951_001752"
     CDS             5417..7804
                     /gene="pheT"
                     /locus_tag="RN951_001752"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HDX2526761.1"
                     /translation="MKFSELWLREWVNPAIDSDALANQITMAGLEVDGVEPVAGSFHG
                     VVVGEVVECAQHPNADKLRVTKVNVGGDRLLDIVCGAPNCRQGLRVAVATIGAVLPGD
                     FKIKAAKLRGEPSEGMLCSFSELGISDDHSGIIELPADAPIGTDIREYLKLDDNTIEI
                     SVTPNRADCLGIIGVARDVAVLNQLPLVQPEIVPVGATIDDTLPITVEAPEACPRYLG
                     RVVKGINVKAPTPLWMKEKLRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIEGGI
                     VVRMAKEGETLVLLDGTEAKLNADTLVIADHNKALAMGGIFGGEHSGVNDETQNVLLE
                     CAFFSPLSITGRARRHGLHTDASHRYERGVDPALQHKAMERATRLLIDICGGEAGPVI
                     DITNEATLPKRATITLRRSKLDRLIGHHIADEQVTDILRRLGCEVTEGKDEWQAVAPS
                     WRFDMEIEEDLVEEVARVYGYNNIPDEPVQASLIMGTHREADLSLKRVKTLLNDKGYQ
                     EVITYSFVDPKVQQMIHPGVEALLLPSPISVEMSAMRLSLWTGLLATVVYNQNRQQNR
                     VRIFESGLRFVPDTQAPLGIRQDLMLAGVICGNRYEEHWNLAKETVDFYDLKGDLESV
                     LDLTGKLNEVEFRAEANPALHPGQSAAIYLKGERIGFVGVVHPELERKLDLNGRTLVF
                     ELEWNKLADRVVPQAREISRFPANRRDIAVVVAENVPAADILSECKKVGVNQVVGVNL
                     FDVYRGKGVAEGYKSLAISLILQDTSRTLEEEEIAATVAKCVEALKERFQASLRD"
     gene            7809..8108
                     /gene="ihfA"
                     /locus_tag="RN951_001753"
     CDS             7809..8108
                     /gene="ihfA"
                     /locus_tag="RN951_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit alpha"
                     /protein_id="HDX2526762.1"
                     /translation="MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQV
                     KLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKDE"
     gene            8209..9189
                     /gene="btuC"
                     /locus_tag="RN951_001754"
     CDS             8209..9189
                     /gene="btuC"
                     /locus_tag="RN951_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter permease BtuC"
                     /protein_id="HDX2526763.1"
                     /translation="MLTLARQQQRQNIRWLLCLSVLMLLALLLSLCAGEQWISPGDWF
                     TPRGELFVWQIRLPRTLAVLLVGAALAISGAVMQALFENPLAEPGLLGVSNGAGVGLI
                     AAVLLGQGQLPNWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALM
                     TWAIYFSTSVDLRQLMYWMMGGFGGVDWRQSWLMLALIPVLLWICCQSRPMNMLALGE
                     ISARQLGLPLWFWRNVLVAATGWMVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLL
                     PGCALAGASALLLADIVARLALAAAELPIGVVTATLGAPVFIWLLLKAGR"
     gene            9252..9803
                     /gene="btuE"
                     /locus_tag="RN951_001755"
     CDS             9252..9803
                     /gene="btuE"
                     /locus_tag="RN951_001755"
                     /EC_number="1.11.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional thioredoxin/glutathione peroxidase"
                     /protein_id="HDX2526764.1"
                     /translation="MQDSILTTVVKDIDGEVTTLEKFAGNVLLIVNVASKCGLTPQYE
                     QLENIQKAWVDRGFMVLGFPCNQFLEQEPGSDEEIKTYCTTTWGVTFPMFSKIEVNGE
                     GRHPLYQKLIAAAPTAVAPEESGFYARMVSKGRAPLYPDDILWNFEKFLVGRDGKVIQ
                     RFSPDMTPEDPIVMESIKLALAK"
     gene            9803..10552
                     /gene="btuD"
                     /locus_tag="RN951_001756"
     CDS             9803..10552
                     /gene="btuD"
                     /locus_tag="RN951_001756"
                     /EC_number="7.6.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter ATP-binding protein
                     BtuD"
                     /protein_id="HDX2526765.1"
                     /translation="MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLA
                     RMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFAMPVWHYLTLHQHDKT
                     RTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEP
                     MNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRRE
                     EVLTPPNLAQAYGMNFRRLDIEGHRMLISTI"
     gene            10630..11094
                     /locus_tag="RN951_001757"
     CDS             10630..11094
                     /locus_tag="RN951_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase"
                     /protein_id="HDX2526766.1"
                     /translation="MRFCLILITALLLAGCSHHKAPPPNARLSDSITVIAGLNDQLQS
                     WHGTPYRYGGMTRRGVDCSGFVVVTMRDRFDLQLPRETKQQASIGTQIDKDELLPGDL
                     VFFKTGSGQNGLHVGIYDTNNQFIHASTSKGVMRSSLDNVYWQKNFWQARRI"
     gene            11341..12054
                     /gene="ydiV"
                     /locus_tag="RN951_001758"
     CDS             11341..12054
                     /gene="ydiV"
                     /locus_tag="RN951_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-FlhDC factor"
                     /protein_id="HDX2526767.1"
                     /translation="MKIFLENLYHSDCYFLPIRDNQQVLVGVELITHFSSEDGTVRIP
                     TSRVIAQLTEEQHWQLFSEQLELLKSCQHFFIQHKLFAWLNLTPQVATLLLERDNYAG
                     ELLKYPFIELLINENYPHLNEGKDNRGLLSLSQVYPLVLGNLGAGNSTMKAVFDGLFT
                     RVMLDKSFIQQQITHRSFEPFIRAIQAQISPCCNCIIAGGIDTAEILAQITPFDFHAL
                     QGCLWPAVPINQITTLVQR"
     gene            12117..13553
                     /locus_tag="RN951_001759"
     CDS             12117..13553
                     /locus_tag="RN951_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiU family protein"
                     /protein_id="HDX2526768.1"
                     /translation="MTLSFVTRWRDELPETYTALSPTPLNNARLIWHNTELANTLSIP
                     SSLFKNGAGVWGGEALLPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGTTM
                     DWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRE
                     TAEPGAMLMRVAPSHLRFGHFEHFYYRRESEKVRQLADFAIRHYWSHLADDEDKYRLW
                     FSDVVARTASLIAQWQTVGFAHGVMNTDNMSLLGLTLDYGPFGFLDDYEPGFICNHSD
                     HQGRYSFDNQPAVALWNLQRLAQTLSPFVAVDALNEALDSYQQVLLTHYGERMRQKLG
                     FMTEQKEDNALLNELFSLMARERSDYTRTFRMLSLTEQHSAASPLRDEFIDRAAFDDW
                     FARYRGRLQQDEVSDSERQQLMQSVNPALVLRNWLAQRAIEAAEKGDMTELHRLHEAL
                     RNPFSDRDDDYVSRPPDWGKRLEVSCSS"
     gene            complement(13557..13748)
                     /gene="hemP"
                     /locus_tag="RN951_001760"
     CDS             complement(13557..13748)
                     /gene="hemP"
                     /locus_tag="RN951_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemin uptake protein HemP"
                     /protein_id="HDX2526769.1"
                     /translation="MRYTDSRKLTPETDANHKTASPQPIRRISSQTLLGPDGKLIIDH
                     DGQEYLLRKTQAGKLLLTK"
     gene            complement(13880..14926)
                     /gene="aroH"
                     /locus_tag="RN951_001761"
     CDS             complement(13880..14926)
                     /gene="aroH"
                     /locus_tag="RN951_001761"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroH"
                     /protein_id="HDX2526770.1"
                     /translation="MNRTDELRTARIESLVTPAELALRYPVTPGVATHVTDSRRRIEK
                     ILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRNQYQSRLEIVMRTYFEKPRTVVG
                     WKGLISDPDLNGSYRVNHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGA
                     IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMT
                     IYQTSGNPYGHIIMRGGKKPNYHADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRR
                     QLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGSQPLTYGQSITDPCLGWEDTE
                     RLVEKLASAVDTRF"
     gene            complement(15083..15916)
                     /gene="ppsR"
                     /locus_tag="RN951_001762"
     CDS             complement(15083..15916)
                     /gene="ppsR"
                     /locus_tag="RN951_001762"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="posphoenolpyruvate synthetase regulatory
                     kinase/phosphorylase PpsR"
                     /protein_id="HDX2526771.1"
                     /translation="MDNAVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVE
                     NESRARAVKDQIDAIYHQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQ
                     EMKLDPTPIAHRTHGLNPNNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSR
                     CGKTPTSLYLAMQFGIRAANYPFIADDMDNLVLPASLKPLQHKLFGLTIDPERLAAIR
                     EERRENSRYASLRQCRMEVAEVEALYRKNQIPWINSTNYSVEEIATKILDIMGLSRRM
                     Y"
     gene            16249..18627
                     /gene="ppsA"
                     /locus_tag="RN951_001763"
     CDS             16249..18627
                     /gene="ppsA"
                     /locus_tag="RN951_001763"
                     /EC_number="2.7.9.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate synthase"
                     /protein_id="HDX2526772.1"
                     /translation="MSNNGSSPLVLWYNQLGMNDVDRVGGKNASLGEMITNLSGMGVS
                     VPNGFATTADAFNQFLDQSGVNQRIYELLDKTDIDDVTQLAKAGAQIRQWIIDTPFQP
                     ELENAIREAYAQLSADDENASFAVRSSATAEDMPDASFAGQQETFLNVQGFDAVLVAV
                     KHVFASLFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQV
                     VFITSAWGLGEMVVQGAVNPDEFYVHKPTLAANRPAIVRRTMGSKKIRMVYAPTQEHG
                     KQVKIEDVPQEQRDIFSLTNEEVQELAKQAVQIEKHYGRPMDIEWAKDGHTGKLFIVQ
                     ARPETVRSRGQVMERYTLHSQGKIIAEGRAIGHRIGAGPVKVIHDISEMNRIEPGDVL
                     VTDMTDPDWEPIMKKASAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERMKDGENV
                     TVSCAEGDTGYVYAELLEFSVKSSSVETMPDLPLKVMMNVGNPDRAFDFACLPNEGVG
                     LARLEFIINRMIGVHPRALLEFDDQEPQLQNEIREMMKGFDSPREFYVGRLTEGIATL
                     GAAFYPKRVIVRLSDFKSNEYANLVGGERYEPDEENPMLGFRGAGRYVSDSFRDCFAL
                     ECEAVKRVRNDMGLTNVEIMIPFVRTVDQAKAVVEELARQGLKRGENGLKIIMMCEIP
                     SNALLAEQFLEYFDGFSIGSNDMTQLALGLDRDSGVVSELFDERNDAVKALLSMAIRA
                     AKKQGKYVGICGQGPSDHEDFAAWLMEEGIDSLSLNPDTVVQTWLSLAELKK"
     gene            complement(18684..20330)
                     /gene="fadK"
                     /locus_tag="RN951_001764"
     CDS             complement(18684..20330)
                     /gene="fadK"
                     /locus_tag="RN951_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310435.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="medium-chain fatty-acid--CoA ligase"
                     /protein_id="HDX2526773.1"
                     /translation="MKVTLTFNEQRRAAYRQQGLWGDASLADYWQQTARAMPDKIAVV
                     DNHGASYTYSALDHAASCLANWMLAKGIESGDRIAFQLPGWCEFTVIYLACLKIGAVS
                     VPLLPSWREAELVWVLNKCQAKMFFAPTLFKQTRPVDLILPLQNQLPQLQQIVGVDKL
                     APATSSLSLSQIIADNTSLTTAITTHGDELAAVLFTSGTEGLPKGVMLTHNNILASER
                     AYCARLNLTWQDVFMMPAPLGHATGFLHGVTAPFLIGARSVLLDIFTPDACLALLEQQ
                     RCTCMLGATPFVYDLLNVLEKQPADLSALRFFLCGGTTIPKKVARECQQRGIKLLSVY
                     GSTESSPHAVVNLDDPLSRFMHTDGYAAAGVEIKVVDDARKTLPPGCEGEEASRGPNV
                     FMGYFDEPELTARALDEEGWYYSGDLCRMDEAGYIKITGRKKDIIVRGGENISSREVE
                     DILLQHPKIHDACVVAMSDERLGERSCAYVVLKAPHHSLSLEEVVAFFSRKRVAKYKY
                     PEHIVVIEKLPRTTSGKIQKFLLRKDIMRRLTQDVCEEIE"
     gene            complement(20387..20680)
                     /locus_tag="RN951_001765"
     CDS             complement(20387..20680)
                     /locus_tag="RN951_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin family protein"
                     /protein_id="HDX2526774.1"
                     /translation="MSQNATVNVDIKLGVNKFHVDEGHPHIILAENPDINEFHKLMKA
                     CPAGLYKQDDAGNIHFDSAGCLECGTCRVLCGNTILEQWQYPAGTFGIDFRYG"
     gene            complement(20677..21966)
                     /locus_tag="RN951_001766"
     CDS             complement(20677..21966)
                     /locus_tag="RN951_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDX2526775.1"
                     /translation="MSDDKFDAIVVGAGVAGSVAALVMARAGLDVLVIERGDSAGCKN
                     MTGGRLYAHTLEAIIPGFAVSAPVERKVTREKISFLTEESAVTLDFHREQPDVPQHAS
                     YTVLRNRLDPWLMEQAEQAGAQFIPGVRVDALVREGNKVTGVQAGDDILEANVVILAD
                     GVNSMLGRSLGMVPASDPHHYAVGVKEVIGLTPEQINDRFNITGEEGAAWLFAGSPSD
                     GLMGGGFLYTNKDSISLGLVCGLGDIAHAQKSVPQMLEDFKQHPAIRPLISGGKLLEY
                     SAHMVPEGGLAMVPQLVNEGVMIVGDAAGFCLNLGFTVRGMDLAIASAQAAATTVIAA
                     KERADFSASSLAQYKRELEQSCVMRDMQHFRKIPALMENPRLFSQYPRMVADIMNEMF
                     TIDGKPNQPVRKMIMGHAKKIGLINLLKDGIKGATAL"
     gene            complement(22022..22960)
                     /locus_tag="RN951_001767"
     CDS             complement(22022..22960)
                     /locus_tag="RN951_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit alpha"
                     /protein_id="HDX2526776.1"
                     /translation="MSQLNSVWVFSDNPERYAELFGGAQQWGQQVYAIVQNTDQAQAV
                     MPYGPKCLYVLAQNDALQRTENYAESIAALLKDKHPAMLLLAATKRGKALAARLSVQL
                     NAALVNDATAVDIVDGHICAEHRMYGGLAFAQEKINSPLAIITLAPGVQEPCTSDTSH
                     QCPTETVPYVAPRHEILCRERRAKAASSVDLSKAKRVVGVGRGLAAQDDLKMVHELAA
                     VLNAEVGCSRPIAEGENWMERERYIGVSGVLLKSDLYLTLGISGQIQHMVGGNGAKVI
                     VAINKDKNAPIFNYADYGLVGDIYKVVPALISQLSR"
     gene            complement(22980..23744)
                     /locus_tag="RN951_001768"
     CDS             complement(22980..23744)
                     /locus_tag="RN951_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein"
                     /protein_id="HDX2526777.1"
                     /translation="MKIITCFKLVPEEQDIVVTPEYTLNFDNADAKISQFDLNAIEAA
                     SQLATDDDEIAALTVGGSLLQNSKVRKDVLSRGPHSLYLVQDAQLEHALPLDTAKALA
                     AAIEKIGFDLLIFGEGSGDLYAQQVGLLVGEILQLPVINAVSAIQRQGNTLVIERTLE
                     DDVEVIELSVPAVLCVTSDINVPRIPSMKAILGAGKKPVNQWQASDIDWSQSAPLAEL
                     VGIRVPPQTERKHIIIDNDSPEAIAELAEHLKKALN"
     gene            24060..24971
                     /locus_tag="RN951_001769"
     CDS             24060..24971
                     /locus_tag="RN951_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDX2526778.1"
                     /translation="MYQRCFDNASETLFVAGKTPRLSRFAFSDDPKWESGHHVHDNET
                     ELIYVKKGVARFTIDSSLYVAHADDIVVIERGRLHAVASDVNDPATTCTCALYGFQFQ
                     GAEENQLLQPHSCPVIAAGQGKEVIKTLFNELSVILPQSKNSQTSSLWDAFAYTLAIL
                     YYENFKNAYRSEQGYIKKDVLIKDILFYLNNNYREKITLEQLSKKFRASVSYICHEFT
                     KEYRISPINYVIQRRMTEAKWSLTNTELSQAEISWRVGYENVDHFAKLFLRHVGCSPS
                     DYRRQFKNCFAEQEILSEFPQPVSLVG"
     gene            complement(25014..26165)
                     /locus_tag="RN951_001770"
     CDS             complement(25014..26165)
                     /locus_tag="RN951_001770"
                     /EC_number="1.3.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310429.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HDX2526779.1"
                     /translation="MDFSLTEEQELLLASIRELITTNFPEEYFRTCDQNGTYPREFMR
                     ALADNGISMLGVPEEFGGIPADYVTQMLALMEVSKCGAPAFLITNGQCIHSMRRFGSA
                     EQLRKTAESTLETGDPAYALALTEPGAGSDNNSATTTYTRKNGKVYINGQKTFITGAK
                     EYPYMLVLARDPQPKDPKKAFTLWWVDSSKPGIKINPLHKIGWHMLSTCEVYLDNVEV
                     EESDMVGEEGMGFLNVMYNFEMERLINAARSTGFAECAFEDAARYANQRIAFGKPIGH
                     NQMIQEKLALMAIKIDNMRNMVLKVAWQADQHQSLRTSAALAKLYCARTAMEVIDDAI
                     QIMGGLGYTDEARVSRFWRDVRCERIGGGTDEIMIYVAGRQILKDYQNK"
     gene            complement(26179..27774)
                     /locus_tag="RN951_001771"
     CDS             complement(26179..27774)
                     /locus_tag="RN951_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl CoA:acetate/3-ketoacid CoA transferase"
                     /protein_id="HDX2526780.1"
                     /translation="MKPVKPPRINGRVPVLSAQEAVNYIPDEATLCVLGAGGGILEAT
                     TLITALADKYKQTQTPRNLSIISPTGLGDRADRGISPLAQEGLVKWALCGHWGQSPRI
                     SELAEQNKIIAYNYPQGVLTQTLRAAAAHQPGIISDIGIGTFVDPRQQGGKLNEVTKE
                     DLIKLVEFDNKEYLYYKAIAPDIAFIRATTCDSEGYATFEDEVMYLDALVIAQAVHNN
                     GGIVMMQVQKMVKKATLHPKSVRIPGYLVDIVVVDPDQTQLYGGAPVNRFISGDFTLD
                     DSTKLSLPLNQRKLVARRALFEMRKGAVGNVGVGIADGIGLVAREEGCADDFILTVET
                     GPIGGITSQGIAFGANVNTRAILDMTSQFDFYHGGGLDVCYLSFAEVDQHGNVGVHKF
                     NGKIMGTGGFIDISATSKKIIFCGTLTAGSLKTEITDGKLNIVQEGRVKKFIRELPEI
                     TFSGKIALERGLDVRYITERAVFTLKEDGLHLIEIAPGVDLQKDILDKMDFTPVISPE
                     LKLMDERLFIDAAMGFVLPEAAH"
     gene            complement(27917..28675)
                     /gene="aroD"
                     /locus_tag="RN951_001772"
     CDS             complement(27917..28675)
                     /gene="aroD"
                     /locus_tag="RN951_001772"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDX2526781.1"
                     /translation="MKTVTVKDLVIGTGAPKIIVSLMAKDIASVKSEALAYREADFDI
                     LEWRVDHYADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNR
                     AAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRK
                     MQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKTGVISRLAGEV
                     FGSAATFGAVKKASAPGQISVNDLRTVLTILHQA"
     gene            complement(28706..29572)
                     /gene="ydiB"
                     /locus_tag="RN951_001773"
     CDS             complement(28706..29572)
                     /gene="ydiB"
                     /locus_tag="RN951_001773"
                     /EC_number="1.1.1.282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinate/shikimate dehydrogenase"
                     /protein_id="HDX2526782.1"
                     /translation="MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPFTYMAFEV
                     DNDSFPGAIEGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLR
                     GYNTDGTGHIRAIKESGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRDEF
                     FDKALAFAQRVNENTDCVVTVTDLADQQAFAEALASADILTNGTKVGMKPLENESLVN
                     DISLLHPGLLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFTLWTGKDFP
                     LEYVKQVMGFGA"
     gene            complement(29584..30849)
                     /locus_tag="RN951_001774"
     CDS             complement(29584..30849)
                     /locus_tag="RN951_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416206.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2526783.1"
                     /translation="MSQNKAFSTPFILAVLCIYFSYFLHGISVITLAQNMSSLAEKFS
                     TDNAGIAYLISGIGLGRLISILFFGVISDKFGRRAVILMAVIMYLLFFFGIPACPNLT
                     LAYGLAVCVGIANSALDTGGYPALMECFPKASGSAVILVKAMVSFGQMFYPMLVSYML
                     LNNIWYGYGLIIPGILFVLITLMLLKSKFPSQLVDASVTNELPQMNSKPLVWLEGVSS
                     VLFGVAAFSTFYVIVVWMPKYAMAFAGMSEAEALKTISYYSMGSLVCVFIFAALLKKM
                     VRPIWANVFNSALATITAAIIYLYPSPLVCNAGAFVIGFSAAGGILQLGVSVMSEFFP
                     KSKAKVTSIYMMMGGLANFVIPLITGYLSNIGLQYIIVLDFTFALLALITAIIVFIRY
                     YRVFIIPENDVRFGERKFCTRLNTIKHRG"
     gene            complement(31076..32290)
                     /locus_tag="RN951_001775"
     CDS             complement(31076..32290)
                     /locus_tag="RN951_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2526784.1"
                     /translation="MKNPYFPTALGLYFNYLVHGMGVLLMSLNMASLETLWQTNAAGV
                     SIVISSLGIGRLSVLLFAGLLSDRFGRRPFIMLGMCCYMAFFFGILQTNNIIIAYVFG
                     FLAGMANSFLDAGTYPSLMEAFPRSPGTANILIKAFVSSGQFLLPLIISLLVWAELWF
                     GWSFMIAAGIMFINALFLYRCTFPPHPGRRLPVIKKTTSSTEHRCSIIDLASYTLYGY
                     ISMATFYLVSQWLAQYGQFVAGMSYTMSIKLLSIYTVGSLLCVFITAPLIRNTVRPTT
                     LLMLYTFISFIALFTVCLHPTFYVVIIFAFVIGFTSAGGVVQIGLTLMAERFPYAKGK
                     ATGIYYSAGSIATFTIPLITAHLSQRSIADIMWFDTAIAAIGFLLALFIGLRSRKKTR
                     HHSLKENVAPGG"
     gene            complement(32390..32746)
                     /locus_tag="RN951_001776"
     CDS             complement(32390..32746)
                     /locus_tag="RN951_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416204.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiL family protein"
                     /protein_id="HDX2526785.1"
                     /translation="MNAYELQALRHIFAMTIDECATWIAQTGDSESWRQWENGKCAIP
                     DRVVEQLLAMRQQRKKHLHAIIEKINNRIGNNTMRFFPDLTAFQRVYPDGNFIDWKIY
                     QSVAAELYAHDLERLC"
     gene            complement(32882..32989)
                     /gene="rprA"
                     /locus_tag="RN951_001777"
     ncRNA           complement(32882..32989)
                     /ncRNA_class="antisense_RNA"
                     /gene="rprA"
                     /locus_tag="RN951_001777"
                     /product="antisense sRNA RprA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00034"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00034"
     gene            complement(33175..34287)
                     /gene="ydiK"
                     /locus_tag="RN951_001778"
     CDS             complement(33175..34287)
                     /gene="ydiK"
                     /locus_tag="RN951_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter YdiK"
                     /protein_id="HDX2526786.1"
                     /translation="MVNVRQPRDVAQILLSVLFLAIMIVACLWIVQPFILGFAWAGTV
                     VIATWPVLLRLQKIMFGRRSLAVLVMTLLLVMVFIIPIALLVNSIVDGSGPLIKAISS
                     GDMTLPDLAWLNTIPVIGAKLYAGWHNLLDMGGTAIMAKVRPYIGTTTTWFVGQAAHI
                     GRFMVHCALMLLFSALLYWRGEQVAQGIRHFATRLAGVRGDAAVLLAAQAIRAVALGV
                     VVTALVQAVLGGIGLAVSGVPYATLLTVLMILSCLVQLGPLPVLIPAIIWLYWTGDTT
                     WGTVLLVWSGVVGTLDNVIRPMLIRMGADLPLILILSGVIGGLIAFGMIGLFIGPVLL
                     AVSWRLFAAWVEEVPPPTDQPEEILEELGEIEKPNK"
     gene            34676..37732
                     /locus_tag="RN951_001779"
     CDS             34676..37732
                     /locus_tag="RN951_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDX2526787.1"
                     /translation="MIPQISQAPGVVQLVLNFLQELEQQGFTGDTATSYADRLTMSTD
                     NSIYQLLPDAVVFPRSTADVALIARLAAQERYSSLIFTPRGGGTGTNGQALNQGIIVD
                     MSRHMNRIIEINPEEGWVRVEAGVIKDQLNQYLKPFGYFFAPELSTSNRATLGGMINT
                     DASGQGSLVYGKTSDHVLGVRAVLLGGDILDTQPLPVELAETLGKSNTTIGRIYNTVY
                     QRCRQQRQLIIDNFPKLNRFLTGYDLRHVFNDEMTEFDLTRILTGSEGTLAFITEARL
                     DITRLPKVRRLVNVKYDSFDSALRNAPFMVEARALSVETVDSKVLNLAREDIVWHSVS
                     ELITDVPDQEMLGLNIVEFAGDDEALIDERVNALCARLDELIASHQAGVIGWQVCREL
                     AGVERIYAMRKKAVGLLGNAKGAAKPIPFAEDTCVPPEHLADYIAEFRALLDSHGLSY
                     GMFGHVDAGVLHVRPALDMCDPQQEILMKQISDDVVALTAKYGGLLWGEHGKGFRAEY
                     SPAFFGEELFAELRKVKAAFDPHNRLNPGKICPPEGLDAPMMKVDAVKRGTFDRQIPI
                     AVRQQWRGAMECNGNGLCFNFDARSPMCPSMKITQNRIHSPKGRATLVREWLRLLADR
                     GVDPLKLEQELPESGVSLRTLIARTRNSWHANKGEYDFSHEVKEAMSGCLACKACSTQ
                     CPIKIDVPEFRSRFLQLYHTRYLRPLRDHLVATVESYAPLMARAPKTFNFFINQPLVR
                     KLSEKHIGMVDLPLLSVPSLQQQMVGHRSANMTLEQLESLNAEQKARTVLVVQDPFTS
                     YYDAQVVADFVRLVEKLGFQPVLLPFSPNGKAQHIKGFLNRFAKTAKKTADFLNRMAK
                     LGMPMVGVDPALVLCYRDEYKLALGEERGEFNVLLANEWLASALESQPVATVSGESWY
                     FFGHCTEVTALPGAPAQWAAIFARFGAKLENVSVGCCGMAGTYGHEAKNHENSLGIYE
                     LSWHQAMQRLPRNRCLATGYSCRSQVKRVEGTGVRHPVQALLEIIK"
     gene            37729..38139
                     /gene="menI"
                     /locus_tag="RN951_001780"
     CDS             37729..38139
                     /gene="menI"
                     /locus_tag="RN951_001780"
                     /EC_number="3.1.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA hydrolase"
                     /protein_id="HDX2526788.1"
                     /translation="MIWKRKITLEALNAMGEGNMVGFLDIRFEHIGDDTLEATMPVDS
                     RTKQPFGLLHGGASVVLAESIGSVAGYLCTEGEQKVVGLEINANHVRSAREGRVRGVC
                     KPLHLGSRHQVWQIEIFDEKGRLCCSSRLTTAIL"
     gene            38239..38427
                     /locus_tag="RN951_001781"
     CDS             38239..38427
                     /locus_tag="RN951_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416200.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiH family protein"
                     /protein_id="HDX2526789.1"
                     /translation="MSTQLDPTQLAIEFLRRDQSNLSPAQYLKRLKQLELEFADLLTL
                     SSAELKEEIYFAWRLGVH"
     gene            38975..39343
                     /gene="sufA"
                     /locus_tag="RN951_001782"
     CDS             38975..39343
                     /gene="sufA"
                     /locus_tag="RN951_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold SufA"
                     /protein_id="HDX2526790.1"
                     /translation="MDMHSGTFNPQDFAWQGLTLTPAAAIHIRELVAKQPGMVGVRLG
                     VKQTGCAGFGYVLDSVSEPDKDDLLFEHDGAKLFVPLQAMPFIDGTEVDFVREGLNQI
                     FKFHNPKAQNECGCGESFGV"
     gene            39352..40839
                     /gene="sufB"
                     /locus_tag="RN951_001783"
     CDS             39352..40839
                     /gene="sufB"
                     /locus_tag="RN951_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416198.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HDX2526791.1"
                     /translation="MSRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVR
                     AISAKRNEPEWMLEFRLNAYRAWLEMEEPHWLKAHYDKLNYQDYSYYSAPSCGNCDDT
                     CASEPGAVQQTGANAFLSKEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLA
                     EQGIIFCSFGEAIHDHPELVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCP
                     MELSTYFRINAEKTGQFERTILVADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKN
                     AEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSETGSAITWKYPSCIL
                     RGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTKSTIISKGISAGHSQNSYRGLVKI
                     MPTATNARNFTQCDSMLIGANCGAHTFPYVECRNNRAQLEHEATTSRIGEDQLFYCLQ
                     RGISEEDAISMIVNGFCKDVFSELPLEFAVEAQKLLAISLEHSVG"
     gene            40849..41595
                     /gene="sufC"
                     /locus_tag="RN951_001784"
     CDS             40849..41595
                     /gene="sufC"
                     /locus_tag="RN951_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HDX2526792.1"
                     /translation="MLSIKDLHVSVEDKAILRGLSLDVHPGEVHAIMGPNGSGKSTLS
                     ATLAGREDYEVTGGTVEFKGKDLLALSPEDRAGEGIFMAFQYPVEIPGVSNQFFLQTA
                     LNAVRSYRGQETLDRFDFQDLMEEKIALLKMPEDLLTRSVNVGFSGGEKKRNDILQMA
                     VLEPELCILDESDSGLDIDALKVVADGVNSLRDGKRSFIIVTHYQRILDYIKPYYVHV
                     LYQGRIVKSGDFTLVKQLEEQGYGWLTEQQ"
     gene            41570..42841
                     /gene="sufD"
                     /locus_tag="RN951_001785"
     CDS             41570..42841
                     /gene="sufD"
                     /locus_tag="RN951_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HDX2526793.1"
                     /translation="MAGLPNSSNALQQWHHLFEAEGTKRSPQAQQHLQQLLRTGLPTR
                     KHENWKYTPLEGLINSQFVSIAGEISPQQRDALALTLDSVRLVFVDGRYVPALSDATE
                     GSGYEVSINDDRQGLPDAIQAEVFLHLTESLAQSVTHIAVKRGQRPAKPLLLMHITQG
                     VAGEEVNTAHYRHHLDLAEGAEATVIEHFVSLNDARHFTGARFTINVAANAHLQHIKL
                     AFENPLSHHFAHNDLLLAEDATAFSHSFLLGGAVLRHNTSTQLNGENSTLRINSLAMP
                     VKNEVCDTRTWLEHNKGFCNSRQLHKTIVSDKGRAVFNGLINVAQHAIKTDGQMTNNN
                     LLMGKLAEVDTKPQLEIYADDVKCSHGATVGRIDDEQIFYLRSRGINQQDAQQMIIYA
                     FAAELTEALRDEGLKQQVLARIGQRLPGGAR"
     gene            42838..44058
                     /gene="sufS"
                     /locus_tag="RN951_001786"
     CDS             42838..44058
                     /gene="sufS"
                     /locus_tag="RN951_001786"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase SufS"
                     /protein_id="HDX2526794.1"
                     /translation="MIFSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDAEA
                     EFYRHGYAAVHRGIHTLSAQATEKMENVRKRASLFINARSAEELVFVRGTTEGINLVA
                     NSWGNSNVRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLETLPTL
                     FDEKTRLLAITHVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMHHPVDVQALDCD
                     FYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEA
                     GTPNTGGIIGLGAALEYVSALGLNNIAEYEQNLMHYALSQLESVPDLTLYGPQNRLGV
                     IAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASLAMYNTHEEVD
                     RLVTGLQRIHRLLG"
     gene            44071..44487
                     /gene="sufE"
                     /locus_tag="RN951_001787"
     CDS             44071..44487
                     /gene="sufE"
                     /locus_tag="RN951_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfuration protein SufE"
                     /protein_id="HDX2526795.1"
                     /translation="MALLPDKEKLLRNFLRCANWEEKYLYIIELGQRLPELRDEDRSP
                     QNSIQGCQSQVWIVMRQNAQGIIELQGDSDAAIVKGLIAVVFILYDQMTPQDIVNFDV
                     RPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAAALS"
     gene            44636..45640
                     /gene="ldtE"
                     /locus_tag="RN951_001788"
     CDS             44636..45640
                     /gene="ldtE"
                     /locus_tag="RN951_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase LdtE"
                     /protein_id="HDX2526796.1"
                     /translation="MKRASLLTLTLIGAFSAIQAAWAVDYPLPPTGSRLVGQNQTYTV
                     QEGDKNLQAIARRFDTAAMLILEANNTIAPVPKPGTTITIPSQLLLPDAPRQGIIVNL
                     AELRLYYYPPGENIVQVYPIGIGLQGLETPVMETRVGQKIPNPTWTPTAGIRQRSLER
                     GIKLPPVVPAGPNNPLGRYALRLAHGNGEYLIHGTSAPDSVGLRVSSGCIRMNAPDIK
                     ALFSSVRTGTPVKVINEPVKYSVEPNGMRYVEVHRPLSAEEQQNVQTMPYTLPAGFTQ
                     FKDNKAVDQKLVDKALYRRAGYPVSVSSGATPAASNAPSVESAQNGEPEQGNMLRVTQ
                     "
     gene            complement(45704..45940)
                     /gene="lpp"
                     /locus_tag="RN951_001789"
     CDS             complement(45704..45940)
                     /gene="lpp"
                     /locus_tag="RN951_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein lipoprotein Lpp"
                     /protein_id="HDX2526797.1"
                     /translation="MKATKLVLGAVILGSTLLAGCSSNAKIDQLSSDVQTLNAKVDQL
                     SNDVNAMRSDVQAAKDDAARANQRLDNMATKYRK"
     gene            complement(46251..47663)
                     /gene="pykF"
                     /locus_tag="RN951_001790"
     CDS             complement(46251..47663)
                     /gene="pykF"
                     /locus_tag="RN951_001790"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010346010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase PykF"
                     /protein_id="HDX2526798.1"
                     /translation="MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHG
                     QRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGN
                     SEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL
                     PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHII
                     SKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVIT
                     ATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICER
                     TDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFP
                     DATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVV
                     MVSGALVPSGTTNTASVHVL"
     gene            48220..48429
                     /gene="fumD"
                     /locus_tag="RN951_001791"
     CDS             48220..48429
                     /gene="fumD"
                     /locus_tag="RN951_001791"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase FumD"
                     /protein_id="HDX2526799.1"
                     /translation="MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTA
                     LANKRIQRSELEKQAMETVINALVK"
BASE COUNT        12298 a        11692 c        12503 g        11993 t
ORIGIN      
        1 ttctgtatgg atgggtgaag tggcaaagtt aatggtaaaa agggcagtgg aataacaatt
       61 ttgtgatatt tttcgacagt ttgcggtaaa ttcctgagta acacagtatg acagcatcga
      121 acttaagtca gaggtatcaa gtagggtgat gagctggcgc gcaaattgat taataggctc
      181 tgatgaaggt gttggtatgt cgctatcgat gtgcaatcta tgaggagact tataatgagt
      241 tctgataatg atatcgtttt gactcataat ctgttcgcct tatatatatc tggaggtttt
      301 gaggatgatg attaattatt atcgccagaa cgaaatgtgc acgaaaaatt gttataagaa
      361 ttgtgtcact tttatcattg tgatatgacc acttcgtcat taatctcatg agcgtttaaa
      421 atactaccgc caaatcacgc aacgaacttt gctggattca gtttatgctg ctgtaaatcc
      481 gctcgcagta aacctttcag acgcaccgtg atgttatcag ttgttcttta agcgttttgc
      541 tggtgtactc actacaaacg aattgcgaat cgaatcaatg tgaaacggaa aggtacaatc
      601 tccctttttt tagtgttaac atcgctcaac cgggtggaag gtgagaggtt aatgtctttc
      661 atttgtgtac ctgattgcga accaatttag catttgttgg ctagatggtt tcgcaatgaa
      721 ctgttaataa acaaattttt ctttgtatgt gatctttcgt gtgggtcacc actgcaaata
      781 aggatataaa atgcctgtta taactcttcc tgatggcagc caacgccatt acgatcacgc
      841 tgtaagcccc atggatgttg cgctggacat tggtccaggt ctggcgaaag cctgtatcgc
      901 agggcgcgtt aatggcgaac tggttgatgc ttgcgatctg attgaaaacg acgcacaact
      961 gtcgatcatt accgccaaag acgaagaagg tctggagatc attcgtcact cctgtgcgca
     1021 cctgttaggg cacgcgatta aacaactttg gccgcatacc aaaatggcaa tcggcccggt
     1081 tattgacaac ggtttttatt acgacgttga tcttgaccgc acgttaaccc aggaagatgt
     1141 cgaagcactc gagaagcgga tgcatgagct tgctgagaaa aactacgacg tcattaagaa
     1201 gaaagtcagc tggcacgaag cgcgtgaaac tttcgccaac cgtggggaga gctacaaagt
     1261 ctccattctt gacgaaaaca tcgcccatga tgacaagcca ggtctgtact tccatgaaga
     1321 atatgtcgat atgtgccgcg gtccgcacgt accgaacatg cgtttctgcc atcatttcaa
     1381 actaatgaaa acggcagggg cttactggcg tggcgacagc aacaacaaaa tgttgcaacg
     1441 tatttacggt acggcgtggg cagacaaaaa agcacttaac gcttacctgc agcgcctgga
     1501 agaagccgcg aaacgcgacc accgtaaaat cggtaaacag ctcgacctgt accatatgca
     1561 ggaagaagcg ccgggtatgg tattctggca caacgacggc tggaccatct tccgtgaact
     1621 ggaagtgttt gttcgttcta aactgaaaga gtaccagtat caggaagtta aaggtccgtt
     1681 catgatggac cgtgtcctgt gggaaaaaac cggtcactgg gacaactaca aagatgcaat
     1741 gttcaccaca tcttctgaga accgtgaata ctgcattaag ccgatgaact gcccgggtca
     1801 cgtacaaatt ttcaaccagg ggctgaagtc ttatcgcgat ctgccgctgc gtatggccga
     1861 gtttggtagc tgccaccgta acgagccgtc aggttcgctg catggcctga tgcgcgtgcg
     1921 tggatttacc caggatgacg cgcatatctt ctgtactgaa gaacaaattc gcgatgaagt
     1981 taacggatgt atccgtttag tctatgatat gtacagcact tttggcttcg agaagatcgt
     2041 cgtcaaactc tctactcgtc ctgaaaaacg tattggcagc gacgaaatgt gggatcgtgc
     2101 tgaggcggac ctggcggttg cgctggaaga aaacaacatc ccgtttgaat atcaactggg
     2161 tgaaggcgct ttctacggtc cgaaaattga atttaccctg tatgactgcc tcgatcgtgc
     2221 atggcagtgc ggtacagtac agctggactt ctctttgccg tctcgtctga gcgcttctta
     2281 tgtaggcgaa gacaatgaac gtaaagtacc ggtaatgatt caccgcgcaa ttctggggtc
     2341 gatggaacgt ttcatcggta tcctgaccga agagttcgct ggtttcttcc cgacctggct
     2401 tgcgccggtt caggttgtta tcatgaatat taccgattca cagtctgaat acgttaacga
     2461 attgacgcaa aaactatcaa atgcgggcat tcgtgttaaa gcagacttga gaaatgagaa
     2521 gattggcttt aaaatccgcg agcacacttt gcgtcgcgtc ccatatatgc tggtctgtgg
     2581 tgataaagag gtggaatcag gcaaagttgc cgttcgcacc cgccgtggta aagacctggg
     2641 aagcatggac gtaaatgaag tgatcgagaa gctgcaacaa gagattcgca gccgcagtct
     2701 taaacaattg gaggaataag gtattaaagg cggaaaacga gttcaaacgg cgcgccctaa
     2761 ccgtatcaat ggcgaaattc gcgcccagga agttcgctta acaggtctgg aaggcgagca
     2821 gcttggtatt gtgagtctga gagaagctct ggagaaagca gaagaagccg gagtagactt
     2881 agtcgagatc agccctaacg ccgagccgcc ggtttgtcgt ataatggatt acggcaaatt
     2941 cctctatgaa aagagcaagt cttctaagga acagaagaaa aagcaaaaag ttatccaggt
     3001 taaggaaatt aaattccgtc ctggtacaga tgaaggcgac tatcaggtaa aactccgcag
     3061 cctgattcgc tttctcgaag agggtgataa agccaaaatc acgctgcgtt tccgcggtcg
     3121 tgagatggcg caccagcaaa tcggtatgga agtgcttaat cgcgtgaaag acgatttgca
     3181 agaactggca gtggtcgaat ccttcccaac gaagatcgaa ggccgccaga tgatcatggt
     3241 gctcgctcct aagaagaaac agtaaggcct tcaagtagca ctgtctgtgg agccttcggg
     3301 cttcacaggc tttgttcgcc tttgtttcgt ttattaacaa tgcgaagtgg aagttattaa
     3361 aatgccaaaa attaagaccg tacgcggtgc tgctaagcgc ttcaaaaaaa ccggtaaagg
     3421 tggttttaag cacaagcacg ctaacctgcg tcacattctg accaaaaaag cgaccaaacg
     3481 taaacgtcac ctgcgtccga aagccatggt ttccaaaggc gatctgggcc tggtaatcgc
     3541 gtgcctgccg tacgcataag ccgttaacgt ttttaacttt ttaattagaa tatagataca
     3601 ggagagcaca tatggctcgc gtaaaacgtg gtgttattgc acgtgcacgt cacaagaaaa
     3661 ttttgaaaca agctaaaggc tactacggtg cgcgttctcg cgtataccgc gttgccttcc
     3721 aggctgttat caaagctggt cagtatgctt accgtgaccg tcgtcaacgt aagcgtcagt
     3781 tccgtcaact gtggattgcg cgtatcaacg cagcagcacg tcagaacggt atttcttaca
     3841 gcaaattcat caatggcctg aaaaaagcct ctgttgaaat cgaccgtaag atcctggctg
     3901 atatcgcagt attcgacaaa gtagcgttca ccgctctggt tgaaaaagcg aaagcagctc
     3961 tggcataagc cagttgaaag agggagctag tctccctctt ttcgtttcaa cgccatcaaa
     4021 acattgactt ttatcgccgt agccttttca ataaaggtct tttgaagagt accaaaaggt
     4081 aacgcaagca atgaatgctg ctattttccg cttctttttt tactttagca cctgaatcca
     4141 ggaggctagc gcgtgagaag agaaacggaa aacagcgcct gaaagcctcc cagtggaggc
     4201 tttttttgta tgcgcgtttt gaaaaataaa aagcctgtct catcaggtgt aattgtcgca
     4261 gccagactgg acacggccag cgcggagaaa ccggagcgta tttaagtacg tgagaatttc
     4321 gagcacagcc cgggaccaaa atggcaagta aaatagcctg atgggatagg ctctaagtcc
     4381 aacgaaccag tgtcaccact gacacaatga ggaaaaccat gtcacatctc gcagaactgg
     4441 ttgccagtgc gaaggcggcc attagccagg cgtcagatgt tgccgcgtta gataatgtgc
     4501 gcgtcgaata tttgggtaaa aaagggcact taacccttca gatgacgacc ctgcgtgagc
     4561 tgccgccaga agagcgtccg gcagctggtg cggttatcaa cgaagcgaaa gagcaggttc
     4621 agcaggcgct gaatgcgcgt aaagcggaac tggaaagcgc tgcactgaat gcgcgtctgg
     4681 cggcggaaac gattgatgtc tctctgccag gtcgtcgcat tgaaaacggc ggtctgcatc
     4741 cggttacccg taccatcgac cgtatcgaaa gtttcttcgg tgagcttggc tttaccgtgg
     4801 caaccgggcc ggaaatcgaa gacgattatc ataacttcga tgctctgaac attcctggtc
     4861 accacccggc gcgcgctgac cacgacactt tctggtttga cactacccgc ctgctgcgta
     4921 cccagacctc tggcgtacag atccgcacca tgaaagccca gcagccaccg attcgtatca
     4981 tcgcgcctgg ccgtgtttat cgtaacgact acgaccagac tcacacgccg atgttccatc
     5041 agatggaagg tctgattgtt gataccaaca tcagctttac caacctgaaa ggcacgctgc
     5101 acgacttcct gcgtaacttc tttgaggaag atttgcagat tcgcttccgt ccttcctact
     5161 tcccgtttac cgaaccttct gcagaagtgg acgtcatggg taaaaacggt aaatggctgg
     5221 aagtgctggg ctgcgggatg gtgcatccga acgtgttgcg taacgttggc atcgacccgg
     5281 aagtttactc tggtttcgcc ttcgggatgg ggatggagcg tctgactatg ttgcgttacg
     5341 gcgtcaccga cctgcgttca ttcttcgaaa acgatctgcg tttcctcaaa cagtttaaat
     5401 aaggcaggaa tagattatga aattcagtga actgtggtta cgcgaatggg tgaacccggc
     5461 gattgatagc gatgcgctgg caaatcaaat cactatggcg ggcctggaag ttgacggtgt
     5521 agaaccggtt gccggcagct tccacggcgt ggtcgttggt gaagtggttg agtgtgcgca
     5581 gcatccgaac gctgacaaac tgcgtgtgac aaaagtgaat gtcggcggcg atcgcctgct
     5641 ggacatcgtc tgcggtgcgc caaactgccg tcagggcctg cgtgtagcgg tagcgaccat
     5701 tggtgctgtt ctgccgggtg atttcaaaat taaagcggcg aaactgcgtg gcgaaccgtc
     5761 tgaagggatg ctgtgctcct tctctgaact gggcatttct gacgatcaca gcggcattat
     5821 cgaactgcct gcggatgcgc cgattggcac cgatatccgt gaatacctga aacttgatga
     5881 caacaccatc gaaatcagcg tgacgccaaa ccgtgccgac tgcttaggca tcattggtgt
     5941 tgcgcgtgac gttgccgtgc tgaaccagct gccgctggtt caaccggaaa tcgttccggt
     6001 tggtgcgacc atcgacgaca cgctgccgat tacagtcgaa gcgccggaag cctgcccgcg
     6061 ttatcttggc cgtgtggtaa aaggcattaa cgttaaagcg ccaactccgc tgtggatgaa
     6121 agaaaaactg cgtcgttgcg ggatccgttc tatcgatgca gttgttgacg tcaccaacta
     6181 tgtgctgctc gaactgggcc agccgatgca cgctttcgat aaagatcgca ttgaaggcgg
     6241 cattgtggtg cggatggcga aagagggcga aacgctggtg ctgctcgacg gtactgaagc
     6301 gaagctgaat gctgacactc tggtcatcgc cgaccacaac aaggcgctgg cgatgggcgg
     6361 catcttcggt ggcgaacact ctggcgtgaa tgacgaaaca caaaacgtgc tgctggaatg
     6421 cgcgttcttt agcccgctgt ctatcaccgg tcgtgctcgt cgtcatggcc tgcataccga
     6481 tgcgtctcac cgttatgagc gtggcgttga tccggcactg cagcacaaag cgatggaacg
     6541 tgcgacccgt ctgctgatcg acatctgcgg tggtgaggct ggcccggtaa ttgatatcac
     6601 caacgaagca acgctgccga agcgtgcaac catcactcta cgtcgtagca aactggatcg
     6661 cctgatcggc catcatattg cggatgagca ggtaactgac attctgcgtc gtctcggctg
     6721 cgaagtgacc gaaggcaaag acgaatggca ggcagttgcg ccgagctggc gtttcgatat
     6781 ggagattgaa gaagatctgg ttgaagaagt cgcgcgtgtt tacggctaca acaacatccc
     6841 ggatgagccg gtacaggcaa gcctgattat gggtactcac cgtgaagctg acctgtcgct
     6901 caagcgcgtg aaaacgctgc tcaacgacaa aggctatcag gaagtgatca cctacagctt
     6961 cgttgatccg aaagtgcagc agatgatcca tccaggcgtt gaagccttac tgctgccaag
     7021 cccgatctct gttgaaatgt cagcaatgcg tctttctctg tggactggcc tgctggcaac
     7081 cgtggtgtac aaccagaacc gtcagcagaa ccgtgtgcgc attttcgaaa gcggtctgcg
     7141 tttcgtacca gatactcagg caccgttggg cattcgtcag gatctgatgt tagccggtgt
     7201 gatttgcggt aaccgttacg aagagcactg gaacctggca aaagagaccg ttgatttcta
     7261 tgatttgaaa ggcgatcttg aatccgttct cgacctgacc ggtaaactga atgaggttga
     7321 gttccgtgca gaagcgaatc cggcactgca tccggggcaa tccgcagcga tttatctgaa
     7381 aggtgaacgt attggttttg ttggggttgt tcatcctgaa ctggaacgta aactggatct
     7441 taacggtcgc actctggtgt tcgaactgga gtggaacaag ctcgcagacc gcgtggtgcc
     7501 tcaggcgcgc gagatttctc gcttcccggc gaaccgtcgt gacatcgcgg tggtggtcgc
     7561 agaaaacgtt cccgcagcgg atattttatc cgaatgtaag aaagttggcg taaatcaggt
     7621 agttggcgta aacttatttg acgtgtaccg cggtaagggt gttgcggagg ggtataagag
     7681 cctcgccata agcctgatcc tgcaagatac cagccgtaca ctcgaagaag aggagattgc
     7741 cgctaccgtc gccaaatgtg tagaggcatt aaaagagcga ttccaggcat cattgaggga
     7801 ttgaacctat ggcgcttaca aaagctgaaa tgtcagaata tctgtttgat aagcttgggc
     7861 ttagcaagcg ggatgccaaa gaactggttg aactgttttt cgaagagatc cgtcgcgctc
     7921 tggaaaacgg cgaacaggtg aaactctctg gttttggtaa cttcgatctg cgtgataaga
     7981 atcaacgccc gggacgtaac ccgaaaacgg gcgaggatat tcccattaca gcacggcgcg
     8041 tggtgacctt cagacccggg cagaagttaa aaagccgggt cgaaaacgct tcgcccaaag
     8101 acgagtaatc tgatctaact aaaaaggccg ctctgcggcc ttttttcttt tcactgtcga
     8161 agagtcaccg taaaatcaac gccatgacac ttcagcagaa cggataccat gctgacactt
     8221 gcccgccaac aacagcgaca aaatattcgc tggttattat gcctgtcagt tttgatgctg
     8281 ctggcgcttc tcttaagcct ttgcgccggt gaacaatgga tctcgccagg tgactggttt
     8341 actcctcgtg gcgaactgtt cgtctggcaa attcgcctgc cacgtacgct ggctgtattg
     8401 ctggttggtg cggcgctggc tatatccggc gctgtaatgc aggcgttgtt tgaaaatcct
     8461 ctggcagaac ctggactact tggcgtctct aacggcgcag gcgtggggct tatcgccgcg
     8521 gtattgcttg ggcaagggca actccccaac tgggcgctag ggctgtgtgc gattgctggc
     8581 gcgcttatca tcactttaat actcttacgt ttcgcccgtc gtcatctttc gaccagtcgg
     8641 ttattgctgg ctggcgttgc attagggatt atctgtagcg cactaatgac gtgggctatc
     8701 tacttttcca cctcagttga tttgcgtcag ctgatgtact ggatgatggg cggttttggc
     8761 ggcgtagact ggcggcaaag ctggctgatg ctggcattga tccccgtgtt gttgtggatc
     8821 tgttgtcagt ccaggccgat gaatatgtta gcacttggtg agatctcggc gcggcaactg
     8881 ggtttacccc tgtggttctg gcgcaatgtg ctggtggcag cgaccggctg gatggttggc
     8941 gtcagtgtgg cgctggcggg tgctatcggc tttattggtc tggtgatccc ccatattctc
     9001 cggttgtgtg gtttaaccga tcatcgcgta ttacttcccg gctgcgcgct ggcaggggcg
     9061 agcgcattgc tgctggccga tattgtagcg cgcctggcat tagctgccgc agagctgcct
     9121 attggcgtgg tcaccgcaac gttaggtgcg ccggtgttta tctggttatt gttaaaagca
     9181 ggacgttagc cgcaaaaaga cggtctatga ttaaaagcta agatttttac tgaccacacc
     9241 caggagaaac gatgcaagat tccattctga cgaccgtagt gaaagatatc gacggtgaag
     9301 tgaccacgct ggagaagttc gccggtaatg tgctgttgat tgtcaatgtc gcctcaaagt
     9361 gtggcttaac gccgcaatat gagcagttgg agaatattca gaaagcctgg gtcgatcgag
     9421 gttttatggt gctgggattc ccgtgcaacc agtttctgga acaagaaccg ggcagcgatg
     9481 aagagattaa aacttactgt accaccacat ggggggtgac gttcccgatg ttcagtaaga
     9541 ttgaagttaa tggcgaagga cgccatccgc tgtatcaaaa attgattgcc gcagcgccga
     9601 ccgcagtcgc gccggaagag agcggattct atgcccgtat ggtcagcaaa ggccgtgcac
     9661 cgctgtaccc ggatgatatt ttatggaatt ttgaaaaatt cctggttggc agggacggaa
     9721 aagtcatcca gcgtttttcc ccggatatga cgccggaaga tcccattgtg atggaaagca
     9781 ttaaactggc gttggcaaaa taatgtctat tgtgatgcag ttacaagatg ttgcggaatc
     9841 tacccgcctg gggccgcttt ctggcgaggt tcgggctggg gagatcctgc acctggtggg
     9901 gccgaatggc gcgggtaaga gtaccttact ggcgcgaatg gccggaatga ccagcggtaa
     9961 gggaagcatt cagttcgcgg ggcaaccact ggaagcatgg tccgcaacaa aactcgcgct
    10021 gcatcgcgcc tatctttcac aacagcagac gccgccgttt gcaatgccgg tctggcacta
    10081 cctgacactg catcagcacg ataaaacgcg taccgaacta ctgaatgatg tcgcaggggc
    10141 gctggctctt gatgacaaac tcggacgtag caccaatcaa ctttccggcg gtgaatggca
    10201 acgcgtacgt cttgctgcgg tggtgttgca aatcacacca caagccaatc ccgcaggcca
    10261 attgctgctt cttgatgagc cgatgaacag tcttgatgtt gcgcaacaaa gtgcgttaga
    10321 caaaattctg agcgcgctgt gtcagcaagg actggcgatt gtgatgagca gtcacgatct
    10381 caaccacaca ttgcgtcatg cgcatcgggc gtggttgcta aaaggtggaa aaatgctggc
    10441 cagtggacgc agggaagagg tgctcacgcc gccaaatctg gcgcaggcct atgggatgaa
    10501 ttttcgccgt ctggatatcg aaggtcacag aatgctgatt tcgaccatct gatttcatta
    10561 gtatcttgaa aatcgggtaa ttacgacact aaattaatgc aagaataaaa aacagaggaa
    10621 ccgtacggaa tgcgtttctg ccttattttg atcacagcac tgcttctggc cgggtgtagc
    10681 caccataaag caccgccgcc aaatgccaga ctttctgatt cgattaccgt tattgccggt
    10741 ttgaacgacc agctacaaag ctggcatggc acgccgtatc gttatggtgg catgacgcgg
    10801 cgcggtgtgg actgttcggg atttgtggtt gtgacgatgc gcgatcgttt cgatttgcag
    10861 ctgccccgtg aaaccaaaca acaagcctct attggcacgc aaattgataa agacgagttg
    10921 ctgccaggtg acctggtctt tttcaaaacg gggtccggac aaaatggttt gcatgtaggt
    10981 atttacgata ccaacaacca atttatccac gcctctacca gcaagggagt gatgcgttcc
    11041 tcacttgata atgtctattg gcagaaaaat ttctggcagg cgagacgaat ctagtatgtc
    11101 gaaaaatgga cggcgatgat acatcgccgt ccatttactc ctgaatacag tagtattttg
    11161 cagacaaaaa ttccgtaaat ggattattcg tttataatca ggataatcta aaaaaaggac
    11221 ccctgaaaaa gtggttaaca tggaacaaat gaaagttact ccttctgtaa ttgttatgtc
    11281 ttatggcctc atccctttta gccggatact gaaaaacatc cttcgagagg gacggttacc
    11341 atgaagattt ttttggagaa tctttatcat tctgattgct atttcctgcc gataagagac
    11401 aaccagcaag tccttgtcgg cgttgagtta attacccatt tctccagtga agatggtacg
    11461 gttcgtatcc cgacgagtcg ggttatagcg caacttaccg aggagcaaca ttggcaatta
    11521 ttttcagagc agttggaatt actaaaatca tgccaacatt tttttattca acataaactc
    11581 tttgcctggc ttaatttaac gccacaagtg gctacattat tattagagag ggataattac
    11641 gcaggcgaac tattaaaata tccgtttatt gaactgttga ttaatgagaa ttacccgcat
    11701 ctcaatgaag gaaaagataa tcgcggtctt ttatccttat cgcaagtgta tccccttgtg
    11761 ttaggtaatt tgggagcagg caatagcaca atgaaagcgg tttttgatgg tcttttcacc
    11821 cgcgtcatgc tggataaaag ttttattcag caacaaatca cgcaccgctc cttcgaaccg
    11881 tttattcgtg cgatccaggc gcaaatttcc ccttgttgca attgcatcat tgcgggaggc
    11941 attgatacgg cagaaatatt ggcacagatt acccccttcg atttccatgc tctccaggga
    12001 tgcctgtggc ctgccgttcc cataaatcag ataacgacgt tggttcagcg ataacccttc
    12061 tgtttgctgg tgtttaagac gagagtaacc gtctacacta tcaaacagga ggatctatga
    12121 ccctgtcttt tgttacccgc tggcgcgatg aattgccaga aacctataca gcactttccc
    12181 ctacgccttt aaataatgcc cggctgattt ggcataatac cgaactggct aacacgctga
    12241 gtattccatc gtcgctgttt aaaaatggcg caggtgtctg gggcggcgaa gccctactgc
    12301 ctggtatgtc accactggcg caggtttaca gtggtcatca gttcggcgtc tgggcgggcc
    12361 aactgggtga tgggcgcggc attttactcg gcgaacaact gcttgctgat ggcactacaa
    12421 tggactggca tctgaaaggt gctggcctga cgccttattc gcgaatgggt gatggacggg
    12481 cggttttacg ttcgacgata cgagaaagtc tcgccagtga ggcgatgcat tatctgggca
    12541 ttccgacgac ccgcgcgtta agtatcgtca ccagcgattc gccagtgtat cgggaaacgg
    12601 cggagccagg cgcgatgctg atgcgtgtgg caccaagtca tctgcgcttt ggtcatttcg
    12661 aacattttta ctaccgccgc gagtcggaaa aggttcgtca gttagctgac tttgctattc
    12721 gtcattactg gtcacatctt gcagatgatg aggacaaata ccgtctctgg tttagcgatg
    12781 ttgtcgcacg taccgcgtcg ttaattgccc aatggcagac ggtcggcttt gctcatgggg
    12841 tgatgaatac cgacaacatg tcgctgctgg ggctgacgct tgattacggg ccgtttggtt
    12901 ttcttgatga ttacgaaccc ggttttattt gtaatcactc ggatcatcaa gggcgttaca
    12961 gctttgataa tcaacctgcc gtcgcgttgt ggaatttaca gcgtctggcg cagacattgt
    13021 cgccatttgt tgccgtagat gccctgaatg aggccctgga cagctatcag caggttttgt
    13081 tgacgcatta tggagaacgg atgcggcaga aactgggctt catgacggag caaaaagagg
    13141 ataacgcgct actgaatgaa ttattcagtc tgatggcgcg agagcgcagc gattataccc
    13201 gcacattccg catgctgagt ctgaccgagc agcacagcgc ggcgtcaccg ctacgtgatg
    13261 agtttattga tcgtgcggca tttgatgact ggtttgcccg ttatcggggg cgtttgcaac
    13321 aagacgaggt tagcgatagt gagcgtcagc aactgatgca aagcgttaac cccgctctgg
    13381 tattgcgcaa ctggttggcg caacgggcga ttgaagcggc agaaaagggt gatatgacgg
    13441 aattgcaccg cctgcatgag gcgttgcgaa atcctttcag cgacagagat gatgactatg
    13501 tcagtcgtcc acctgactgg ggtaaacggc tggaagtcag ctgctcgagt taaaggctac
    13561 ttggtcaaca gcagcttgcc agcctgagtt ttacggagca gatattcttg cccgtcatga
    13621 tcgataatca gtttgccatc cggacctaac agtgtctggc tggaaattcg ccgaataggc
    13681 tgcggggaag cggtcttgtg attggcatcc gtttcaggcg tgagttttct gctatccgta
    13741 taacgcataa aaattaataa taattgatat aacaatgatt cttattatca atattatggc
    13801 tgaccagagc aagcagtaat ttgttgagaa gacaacaagt tgcgcagaaa tgcccattcc
    13861 gtcaggaatg ggcacgcatt cagaagcggg tatctaccgc agaggcgagt ttttcgacca
    13921 ggcgttcggt atcctcccag cccagacacg ggtcggtaat ggattgaccg taagtgagcg
    13981 gctgactgcc gacgattttt tgcgttcctt cgcgcaggaa actttccgcc ataattccag
    14041 caatcgccgt agagccattg cggatttgct gacaaatatc ctcacaaact tctaactggc
    14101 gacggtgctg cttctggcag ttaccgtggc tgaaatccac caccagatgt tcaggtaaat
    14161 caaactcgtg cagcgtatcg caggctgcgg cgatatcatc ggcatgataa ttcggctttt
    14221 tgccgccacg cataataatg tggccatacg ggttgccgct ggtctgatag atggtcatct
    14281 gaccattttt gtctggcgag aggaacatat ggctggcgcg ggctgcgcgg atagcatcca
    14341 cagcaatccg cgtattgcca tcggtaccat ttttaaaacc taccggacag gagagtgccg
    14401 aagccatttc gcggtggatc tgactttcgg tagtacgtgc gccaatcgcg ccccaactga
    14461 ttaaatcagc aataaactga ccggtcacca tatcgaggaa ctcggtcgcg gttgggacgc
    14521 ccagctcatt tacctgtaaa agtaatttgc gcgccagctc cagaccgtga tttacccgat
    14581 agctgccgtt taaatctgga tcggagatta gtcctttcca gccgacaaca gttcgtggtt
    14641 tttcaaaata ggtgcgcatt acgatttcca gccgtgactg gtactggttg cgcagcgact
    14701 gcagacgggt ggcgtactcc attgcagcgg tgagatcgtg gatcgagcag gggccaataa
    14761 tgaccaacag tcgcttatct tcaccattca gtattttttc aattctgcgg cgggagtcgg
    14821 tgacatgggt ggcgacgcca ggcgttacgg gataccgtag cgcgagttcg gcgggcgtta
    14881 ccaggctctc aatacgcgca gtacggagtt cgtcagttct gttcattaca agtctcagaa
    14941 atttgttgct tctacggcag gactgccggg aagtgatgcg catcacgata aaccaatcgc
    15001 tgctgatttc aagtgcgagg tgtgtcacac ctcgccgggt ggttagcatg ataacaaaaa
    15061 aataagctaa tgcactagtt ctctagtaca ttcggcgact aaggcccatg atatcgagga
    15121 tcttggtggc aatctcttct accgaataat tggtactgtt aatccacggg atctgatttt
    15181 tacggtacaa ggcttccact tccgcgactt ccatcctgca ctgacgaagc gaggcatagc
    15241 gactgttctc ccgacgttcc tcgcgaatcg ccgccagacg ttccgggtcg atagtcaggc
    15301 cgaacaattt atgctgaagc ggtttgagcg acgcgggtag caccagatta tccatatcgt
    15361 cggcaataaa ggggtagttt gccgcgcgga taccaaactg cattgccaga tacagactgg
    15421 tgggggtttt accacagcga gaaacaccga gcaggatcac ctgagcctgg tccagattgc
    15481 gcaacgaaat gccgtcatcg tgggcgaggg tgtaatcaat cgccgcaatg cgcgcatcat
    15541 atttattgag attattaggg ttaaggccat gggtacgatg agcaatcggc gttggatcca
    15601 gtttcatctc ttgttgtagc ggggcaacca gcgcctgaac gatatcctgg caaaagcctt
    15661 cactttgcaa gatgatggcg cgaatctccg gcaacacgat ggagtagaag accagcgggc
    15721 gcacgcctgt ctggtgataa attgcgtcaa tctgatcctt cactgcccgt gcacggctct
    15781 cattttcgac aaacggcagc gtgatgctgc tgatagtgac gggaaattgt gacattactg
    15841 cgtgtcctaa tacctccgca gttattgccg taccatcaga aatataaaaa acgtggcgat
    15901 caacagcatt atccattttg ttcttcccgt gatgcagaca taattctatg aaagcataaa
    15961 ttaaaaacgc acagaagcgt agaacgttat gtctggttta taaaatgaac cttcaatttt
    16021 attttttatg aaaacagcat ttcattttta tggtttcgtt tataccgatg gtttatgtgg
    16081 aaattgtcga agagagcaga tttgcgcaac gctgggatca gtcttaaaaa gtaaaaaaat
    16141 atatttgctt gaacgattca ccgttttttt catccggtta aatatgcaaa gataaatgcg
    16201 cagaaatgtg tttctcaaac cgttcattta tcacaaaagg attgttcgat gtccaacaat
    16261 ggctcgtcac cgctggtgct ttggtataac caactcggca tgaatgatgt agacagggtt
    16321 gggggcaaaa atgcctccct gggtgaaatg attactaatc tttccggaat gggtgtttcc
    16381 gttccgaatg gtttcgccac aaccgccgac gcgtttaacc agtttctgga ccaaagcggc
    16441 gtaaaccagc gcatttatga actgctggat aaaacggata ttgacgatgt tactcagctt
    16501 gcgaaagcgg gcgcgcaaat ccgccagtgg attatcgaca ctcccttcca gcctgagctg
    16561 gaaaacgcca tccgcgaagc ctatgcacag ctttccgccg atgacgaaaa cgcctctttt
    16621 gcggtgcgct cctccgccac cgcagaagat atgccggacg cttcttttgc cggtcagcag
    16681 gaaaccttcc tcaacgttca gggttttgac gccgttctcg tggcagtgaa acatgtattt
    16741 gcttctctgt ttaacgatcg cgccatctct tatcgtgtgc accagggtta cgatcaccgt
    16801 ggtgtggcgc tctccgccgg tgttcaacgg atggtgcgct ctgacctcgc atcatctggc
    16861 gtgatgttct ccattgatac cgaatccggc tttgaccagg tggtgtttat cacttccgca
    16921 tggggccttg gtgagatggt cgtgcagggt gcggttaacc cggatgagtt ttacgtgcat
    16981 aaaccgacac tggcggcgaa tcgcccggct atcgtgcgcc gcaccatggg gtcgaaaaaa
    17041 atccgcatgg tttacgcgcc gacccaggag cacggcaagc aggttaaaat cgaagacgta
    17101 ccgcaggaac agcgtgacat cttctcgctg accaacgaag aagtgcagga actggcaaaa
    17161 caggccgtac aaattgagaa acactacggt cgcccgatgg atattgagtg ggcgaaagat
    17221 ggccacaccg gtaaactgtt cattgtgcag gcgcgtccgg aaaccgtgcg ctcacgcggt
    17281 caggtcatgg agcgttatac gctgcattca cagggtaaga ttatcgccga aggccgtgct
    17341 atcggtcatc gcatcggtgc gggtccggtg aaagtcatcc atgacatcag cgaaatgaac
    17401 cgcatcgaac ctggcgacgt gctggttact gacatgaccg acccggactg ggaaccgatc
    17461 atgaagaaag catctgccat cgtcaccaac cgtggcggtc gtacctgtca cgcggcgatc
    17521 atcgctcgtg aactgggcat tccggcggta gtgggctgtg gagatgcaac agaacggatg
    17581 aaagacggtg agaacgtcac tgtttcttgt gccgaaggtg ataccggtta cgtctatgcg
    17641 gagttgctgg aatttagcgt gaaaagctcc agcgtagaaa cgatgccgga tctgccgttg
    17701 aaagtgatga tgaacgtcgg taacccggac cgtgctttcg acttcgcctg cctaccgaac
    17761 gaaggcgtgg gccttgcgcg tctggaattt atcatcaacc gtatgattgg cgtccaccca
    17821 cgcgcactgc ttgagtttga cgatcaggaa ccgcagttgc aaaacgaaat ccgcgagatg
    17881 atgaaaggtt ttgattctcc gcgtgaattt tacgttggtc gtctgactga agggatcgcg
    17941 acgctgggtg ccgcgtttta tccgaagcgc gtcattgtcc gtctctctga ttttaaatcg
    18001 aacgaatatg ccaacctggt cggtggtgag cgttacgagc cagatgaaga gaacccgatg
    18061 ctcggcttcc gtggcgcggg ccgctatgtt tccgacagct tccgcgactg tttcgcgctg
    18121 gagtgtgaag cagtgaaacg tgtgcgcaac gacatgggac tgaccaacgt tgagatcatg
    18181 atcccgttcg tgcgtaccgt agatcaggcg aaagcggtgg ttgaagaact ggcgcgtcag
    18241 gggctgaaac gtggcgagaa cgggctgaaa atcatcatga tgtgtgaaat cccgtccaac
    18301 gccttgctgg ccgagcagtt cctcgaatat ttcgacggct tctcaattgg ctcaaacgat
    18361 atgacgcagc tggcgctcgg tctggaccgt gactccggcg tggtgtctga attgttcgat
    18421 gagcgcaacg atgcggtgaa agcactgctg tcgatggcta tccgtgccgc gaagaaacag
    18481 ggcaaatatg tcgggatttg cggtcagggt ccgtccgacc acgaagactt tgccgcatgg
    18541 ttgatggaag aggggatcga tagcctgtct ctgaacccgg acaccgtggt gcaaacctgg
    18601 ttaagcctgg ctgaactgaa gaaataaaat aaatccccgg cggcgtttag tcgccggggt
    18661 tatgtgatcc ccgaagatga aacttattca atctcttcac agacatcctg cgttaaacgc
    18721 cgcataatat cttttcttaa caaaaacttt tgtattttac ctgaggtagt tcgcggtagt
    18781 ttttcgatta ccacgatatg ttcaggatat ttatattttg cgacccgttt acggctaaaa
    18841 aaagccacta cctcttccag cgataatgaa tgatgcggcg ctttcagcac gacataagcg
    18901 catgatcgtt cacctaaacg ttcatcggac attgcaacca cacaggcatc gtgaatttta
    18961 ggatgctgca ataaaatatc ttccacttca cggctgctaa tattttcgcc gccgcggaca
    19021 ataatatctt ttttgcgtcc ggtaattttt atatagccag cctcatccat acggcagaga
    19081 tcgccgctgt aataccagcc ttcttcatcc agggcacggg cggttaattc aggttcatca
    19141 aaatacccca taaacacatt ggggccacgc gaggcttctt caccttcgca acctggcggt
    19201 aaggtcttgc gtgcgtcatc gaccacttta atctctacac ctgcggcagc gtaaccatcg
    19261 gtgtgcataa agcgcgacaa aggatcatcg agattcacca ccgcatgcgg cgaactttct
    19321 gtggaaccat aaacacttaa taatttaatg ccgcgctgct ggcattcacg cgccactttt
    19381 ttggggattg tggttccgcc gcaaagaaag aaacgcagcg ctgaaaggtc cgcgggttgt
    19441 ttctctagta cattcaaaag atcatagaca aacggcgttg cgccgagcat acaggtgcaa
    19501 cgctgctgct caagcagcgc gagacacgca tcaggagtga aaatatctaa caacacgctg
    19561 cgagcgccaa ttaagaatgg tgccgttacg ccatgcagaa agcccgttgc gtgaccaagt
    19621 ggcgcaggca tcataaagac atcctgccag gtcagattca gtcgcgcgca ataagcccgc
    19681 tcactggcga gaatattgtt atgcgttagc atcacgccct ttggcagacc ctcggttccg
    19741 gaggtaaaca gcaccgcagc taattcatcg ccgtgggtcg ttatcgccgt ggtcagtgag
    19801 gtattgtcgg cgataatctg acttaatgag agggaagagg tggcgggagc cagtttgtcc
    19861 acgccgacaa tttgttgtag ttgtggaagc tgattttgca gcggcaggat taaatctacc
    19921 ggacgcgttt gtttaaacaa cgtcggtgca aagaacattt ttgcctgaca cttattgagc
    19981 acccacacca gttctgcttc ccgccaggaa ggcaacagcg gcacggaaac tgcaccgatt
    20041 ttcaggcagg caagatagat aacggtaaat tcacaccagc caggcagttg aaatgcgatg
    20101 cgatcgcctg attcaatacc cttcgctaac atccagtttg ccagacagct cgcggcgtga
    20161 tcgagcgcgc tataggtgta cgatgcacca tgattatcga ccacggcaat tttgtctggc
    20221 atcgcacgag cggtctgctg ccagtaatcg gccagcgaag catcgcccca taacccttgc
    20281 tgacgatacg ccgcacgacg ttgttcgtta aacgttaatg tcactttcat gttggactct
    20341 cgaaacagaa catcaggccc gagatgcggg cctgtgggat gcatgattag ccgtagcgaa
    20401 aatcaatacc gaaggtgcct gcgggatatt gccactgttc gagaatagtg ttaccgcaca
    20461 gcacccgaca ggtgccgcac tccagacaac cggcggaatc aaaatgaatg tttcctgcgt
    20521 catcctgctt ataaagtccg gcagggcagg ctttcattaa tttatggaat tcattgatat
    20581 cgggattttc cgccagaatg atatgcgggt ggccctcatc aacatggaat ttattgacgc
    20641 ctaatttgat gtcgacgtta accgtagcgt tctggctcat agcgcggttg ctcccttaat
    20701 gccatctttc agcaagttga tcagcccaat tttcttcgca tgtcccatga tcatttttcg
    20761 taccggctgg tttggtttgc cgtcgatggt gaacatctcg ttcatgatgt cggctaccat
    20821 tcgtgggtat tggctaaaca ggcgcgggtt ttccatcagc gccgggatct tgcgaaaatg
    20881 ctgcatatca cgcatgacgc agctttgttc cagctcacgt ttgtattgcg ccagactgct
    20941 ggcggagaaa tccgcgcgtt ctttggcggc gatcaccgtt gtggcggcag cctgagccga
    21001 tgcaatggct aaatccatgc cgcggaccgt aaaacccaaa ttcaggcaga agcctgcggc
    21061 gtcaccaacg atcatcacgc cctcgttaac cagttgcggc accattgcca gaccgccttc
    21121 cggcaccata tgcgcggaat attcaagcag tttgccgccg ctaatcagcg ggcgaatggc
    21181 ggggtgttgt ttaaaatctt ccagcatttg cggcacgctt ttttgcgcat gggcgatatc
    21241 acccaatcca caaaccagcc ccaaggatat ggaatccttg ttggtataga gaaatccccc
    21301 gcccatcagg ccgtcagaag gggaaccggc aaacagccag gcggcacctt cctcgcccgt
    21361 aatattaaag cgatcgttga tctgttctgg tgtgaggcca ataacctctt taacaccaac
    21421 agcgtaatga tgcggatcgg aagcgggaac cattcccagc gagcggccaa gcatcgagtt
    21481 aacgccatca gccagaatca ccacattcgc ttcgagaata tcatccccag cctgcacgcc
    21541 agtgaccttg tttccttcac gaaccagcgc gtcgacgcga acgcctggga taaactgcgc
    21601 gcccgcctgc tcggcttgtt ccatcaacca cgggtccaga cgattacgca atacggtata
    21661 agatgcgtgt tgcggaacat ctggctgctc gcggtgaaaa tcgagggtaa cggcgctttc
    21721 ttcggttaag aaggagattt tctcgcgtgt gaccttgcgt tctaccggcg ctgatactgc
    21781 aaagcctgga atgattgctt caagtgtgtg ggcataaaga cgcccgccgg tcatgttttt
    21841 acatccggca ctgtcgccgc gttctatcac caggacatcc agcccggctc gtgccatgac
    21901 cagtgcggca acgctaccag caacgcccgc accgaccaca atggcatcaa atttgtcatc
    21961 cgacatgcgt tatgctccct tcccgctgcg tttacagcgg gagatgtggt tgaaagggga
    22021 attagcggct caactggcta atcagggcag ggacgacttt gtagatatcg cccaccagac
    22081 cgtagtcggc atagttgaag attggcgcat ttttatcttt attgatggcg acaatcactt
    22141 ttgcgccgtt gccgccaacc atatgctgga tctgcccgga gatccccagc gtcaggtaga
    22201 gatcggattt cagcaacacg ccggagacac cgatataacg ttcacgctcc atccagttct
    22261 cgccttcggc aattggacgt gaacagccga cttcagcatt cagcaccgcc gccagttcgt
    22321 ggaccatttt taggtcatcc tgcgccgcca gtccacgacc gacgccaacc acacgttttg
    22381 ctttgctcag gtccacgctg cttgcggctt tcgcacggcg ttcgcgacag agaatttcat
    22441 gacgcggagc aacataaggt accgtttctg tcgggcactg atgagaggta tcactggtgc
    22501 acggttcctg aacaccgggt gcaagggtaa tgatcgccag cgggctgttg atcttttcct
    22561 gagcgaacgc taacccgcca tacatccggt gttcggcgca aatgtgacca tcgacaatat
    22621 ccaccgccgt ggcatcgttc accagcgccg cattcagttg cacacttaac cgtgctgcca
    22681 gcgctttacc acgtttcgtc gcggccaaca gcaacatagc ggggtgttta tctttcagca
    22741 gggcagcaat gctttcggcg taattttcag tgcgttgcag cgcgtcgttt tgcgcaagaa
    22801 cataaagaca ttttggacca taaggcataa ctgcctgcgc ctggtcggta ttttgtacaa
    22861 tggcatacac ctgttggccc cattgctgag cgccgccaaa cagttcagca taacgttcag
    22921 gattatcgct aaagacccag acgctgttta attgactcat cgtttcttct ccgtaggctt
    22981 cagttcaggg ctttcttcag atgttccgcc agctcggcaa tggcctccgg cgaatcgtta
    23041 tcgataatga tgtgcttacg ttctgtttgc ggcggtacgc gaatgccgac cagttcagca
    23101 agtggcgcgc tctggctcca gtcaatatca cttgcctgcc actgatttac cggtttttta
    23161 cccgcgccga gaatggcttt catcgaagga atgcgtggca cgttaatatc ggaggtgacg
    23221 cagagcacgg ctggaacaga gagttcaata acttcaacat catcttcaag cgtgcgttca
    23281 atcaccagtg tattgccctg acgctgaata gcactcactg cattaatcac cggaagttgc
    23341 agaatttctc cgaccagcaa gccaacctgc tgggcataaa ggtcgccgga accttcacca
    23401 aagatcagta aatcgaagcc gatcttttca attgctgccg ccagcgcttt tgcggtatcg
    23461 agaggcagtg catgttcaag ttgcgcatcc tgcaccaaat acaggctgtg cggcccgcgg
    23521 gatagcacgt ctttgcgcac tttcgagttc tgcaacaatg agccgccaac ggtcagcgcg
    23581 gctatctcat cgtcatctgt tgcgagctgg cttgcagctt caatggcatt gagatcgaac
    23641 tggctgattt tggcgtcggc attgtcgaaa ttcagggtgt attctggagt gacaacaatg
    23701 tcctgttctt caggcaccag cttaaagcag gttattattt tcatgatttc tcctgtgagt
    23761 cgcatacgga accatctccg atggaaggta aaaatggcct gaaaatagtg tgcgatagcg
    23821 gtgcggggtt ttcgacggag caagctgttt tccttgccaa caatcttgca aaaaaaatgc
    23881 gatcgctaaa acaaaagtgc aatttgcggc aatatagtta ttccatgacc gtacaatctt
    23941 gcattcagtg taaataatct tgtttagctc tcgctaaacg cggttgtata accgcaatac
    24001 acgccgtatt ttatccggca tatattgttt ttgcttgctc atggaatagg gaggttgtca
    24061 tgtatcaacg ctgttttgat aacgccagtg aaacgctgtt tgtcgccggt aaaacgccac
    24121 ggctttcacg ttttgcattt agcgatgatc caaaatggga gtccggacat cacgttcatg
    24181 acaatgaaac cgagttgatt tacgtcaaga aaggggttgc aaggtttacc atcgattctt
    24241 cgttatatgt cgcacatgcg gatgacattg tggtgataga acgcggcagg ctgcatgcgg
    24301 tggcctctga cgttaacgat ccggcaacga cgtgtacctg tgcgctgtac ggctttcagt
    24361 ttcagggggc tgaggaaaat cagctactgc aaccgcattc ttgtccggta attgccgcgg
    24421 ggcagggaaa agaagtcata aaaaccttat ttaatgagct aagtgtgatt ttgccgcaaa
    24481 gtaaaaatag ccaaacatct tcgttatggg atgcatttgc ctatacgtta gccattcttt
    24541 actacgaaaa ttttaaaaat gcttatcgtt cggagcaggg gtatattaaa aaagatgttc
    24601 tgataaaaga tattcttttc tatctgaata ataattatcg cgaaaaaatc actttagaac
    24661 agttatcgaa aaaatttcgt gccagcgtca gttatatttg ccatgaattt accaaagagt
    24721 atcgtatttc ccctattaac tatgttattc aacggcgtat gacggaagca aaatggtcac
    24781 tcactaatac tgaattatca caggcagaga tctcctggcg tgtgggttat gaaaatgtcg
    24841 atcactttgc caaactgttt ttgcgccatg tcggttgttc gcccagcgat taccgtagac
    24901 aatttaaaaa ctgttttgcg gaacaagaaa tcctatctga atttcctcaa ccggtaagtc
    24961 ttgttggata aatctggcgg cgcagtttgt taagaagctg cgccgcctgc agattatttg
    25021 ttctgatagt ctttcaggat ctgccgacct gctacgtaaa tcataatttc gtctgtaccg
    25081 ccgccgatac gttcacaacg gacatcacgc cagaagcggg agacgcgcgc ctcatcggta
    25141 tagcccagac cgcccatgat ttgaatcgca tcatcaatga cttccattgc ggtacgtgca
    25201 cagtacagtt ttgccagcgc cgcgctggtg cgcagtgact gatgctgatc ggcttgccat
    25261 gccactttca gcaccatgtt gcgcatgttg tcgatcttaa tcgccatcag cgccagtttt
    25321 tcctggatca tctggttatg accaatgggc ttaccaaaag cgatacgttg gttggcatag
    25381 cgggcggcat cttcaaaggc gcattcggca aagccggtgc tgcgcgcggc gttgatcagg
    25441 cgctccatct caaagttgta catcacattg aggaaaccca ttccttcttc gcccaccatg
    25501 tcgctctctt caacctccac gttgtcgaga tagacttcgc aggtgctgag catatgccag
    25561 ccgattttat gcagcgggtt aatcttaatg ccgggcttac tggagtcgac ccaccacagg
    25621 gtgaaggctt ttttgggatc tttcggttgc ggatcgcgcg ccagcaccag catatacggg
    25681 tactctttcg caccggtaat aaaggttttt tgtccgttga tgtagacctt gccgttttta
    25741 cgcgtgtaag tggtagtggc actgttgtta tctgagccag cacctggttc cgtcaacgcc
    25801 agggcatagg cgggatcacc cgtttccagg gtgctctctg ccgttttacg tagctgctct
    25861 gcagaaccga aacggcgcat actgtgaata cattgaccgt tggtaattaa aaatgccgga
    25921 gcaccgcatt ttgacacttc catcagcgcc agcatttggg tgacgtaatc cgcagggata
    25981 ccaccaaatt cttccggcac gccaagcatg gaaataccgt tatccgccag cgcccgcata
    26041 aactcacgcg gatatgtccc gttttgatcg caggtgcgga aatactcttc cggaaagtta
    26101 gtcgtaatca gttcgcgaat actggccagc agcagttctt gttcttcagt taaagaaaaa
    26161 tccatcatta tactcctgtt aatgagccgc ttcaggcagg acaaaaccca tcgccgcatc
    26221 gataaataat ctttcgtcca tcagtttgag ttctggcgaa atcactgggg tgaaatccat
    26281 tttgtcgaga atatcttttt gtaaatcgac gccaggggcg atttcgatta aatgcaggcc
    26341 gtcttctttc agcgtgaata ctgcgcgctc agtgatataa cgaacatcca gccctcgctc
    26401 gagagcgatt tttccgctga aagtaatttc cggtagttcc cgaataaatt tcttcacccg
    26461 tccttcctgg acgatattta atttgccgtc ggtaatttct gtttttaaac tgcccgcagt
    26521 taatgtgccg cagaaaatga ttttcttcga agtggcactg atatcaataa atccaccggt
    26581 gcccatgatt ttaccattga atttatgcac gccgacgtta ccgtgctggt cgacttcagc
    26641 aaaactcaaa taacaaacat ccagaccgcc accgtgataa aaatcaaact gggacgtcat
    26701 atccagaatg gcacgggtat tcacgttcgc gccaaaggcg atcccctgtg aagtaattcc
    26761 gccaatcgga cctgtttcta ccgtcagaat aaagtcatca gcacaacctt cttctcgggc
    26821 gaccaggcca atgccgtcag caataccgac gccgacattc cccaccgcgc ctttacgcat
    26881 ttcgaataat gcgcgccgcg caactaattt acgttggttt aggggcaggc taagtttggt
    26941 actgtcatca agggtgaagt caccagaaat aaagcggtta accggtgcac cgccatacag
    27001 ttgggtttga tccggatcga ccaccacaat atccaccaga taacccggaa tacggacaga
    27061 tttaggatgc agcgtggctt tcttaaccat tttctgcacc tgcatcatca caataccgcc
    27121 gttattgtgc accgcctggg caataaccaa tgcgtcgaga tacatcacct catcttcaaa
    27181 agtggcgtag ccttcactgt cgcaggtggt agcgcgaatg aaggcaatat ctggcgcaat
    27241 cgctttgtaa tagagatatt ctttgttatc aaactcgacc agtttaatca ggtcttcttt
    27301 agtgacttca ttcagtttgc cgccttgctg gcgtggatcg acaaatgtcc cgatgccaat
    27361 atcactaata ataccaggct ggtgggctgc ggcggcgcgt aaggtttgtg taagtacacc
    27421 ttgtgggtag ttataagcaa taattttatt ttgttctgcg agttcagaaa tacgcggcga
    27481 ttgtccccag tgaccacata atgcccattt caccagacct tcttgcgcca gaggactaat
    27541 accacggtcg gcgcgatcgc caagccctgt tggactaata atcgataaat tacgtggtgt
    27601 ttgagtctgt ttatatttat cagcaagagc agtaattaac gtggtggctt ccagaatacc
    27661 gccgccagcg cctaacacac aaagtgttgc ttcgtcggga atataattca ccgcttcctg
    27721 tgccgacagg accggcactc gtccattaat acgaggtggt tttacaggtt tcattgttaa
    27781 ttcctgattc agatgtgatt ttccctacgt caaatggaga attagcgcac agagactcac
    27841 gaaatatttt tattaaatac gattgaatat attttttagt tcggcgggga gggtgttccc
    27901 gccgaaatat tattgcttat gcctggtgta aaatagttaa taccgtgcgc aaatcattta
    27961 ccgagatttg ccctggcgca gacgcttttt ttaccgcacc aaaagttgcc gccgagccaa
    28021 atacttcacc agccagacga gaaattacgc cagtttttgc catcgacatc gtgataattg
    28081 gacgatcggc atactgctcc tgcatctcca gggtcgcggc aagcaacgtc agcacatcgc
    28141 tggtactttg cggcatcagc gcaatcttag gaatatcggc gtcgaaggat tgcattttgc
    28201 gcagacgggc aatgatttct tcggcttccg gcgttttatg gaagtcatgg ttggacatga
    28261 ctactttcac atcatgcgcg tgggcgtagg cgacggtttc tttaacctga tcatcaccgg
    28321 taaataactc cagatcgatc atatcaacca ggccgctgtc gatggctgca cgattgagtg
    28381 caatataagc ctcggtggaa atcgcctgct cgccgccttc tttggcactg cggaaggtaa
    28441 acagcagcgg tttttctggc atggtctcac ggagaatttt tgctgccgcc atgacagact
    28501 ccacattgga gaggtcggca tagtggtcca cacgccattc cagaatatca aagtccgctt
    28561 cacgataggc gagagcttcg gatttcacgc tggcgatatc tttcgccatc agcgagacga
    28621 tgattttagg tgcgcccgta ccaatgacga gatcttttac agttacggtt ttcatttttt
    28681 accctttctg cacgcggtca gcctgtcagg caccgaaccc catgacctgt ttaacatatt
    28741 ccagagggaa atctttgcca gtccataatg tgaactgttc agccccttgc cacaacaaca
    28801 tgccgtatcc atcaatcgtt ttgcaaccag cttgttgcgc ctgctgcaat aacttcgtca
    28861 tatgcgggtt atacacgcat tcagtgacca gaagtcccgg atgtaacaga ctgatatcat
    28921 taaccaatga ttcattctca aggggtttca tacccacttt tgtgccattg gttaaaatgt
    28981 cggcggaagc cagggcttca gcaaaggctt gctgatcggc gagatcggtg accgtgacga
    29041 cacaatcggt gttttcatta acccgctgcg cgaaggcgag ggctttatcg aagaactcat
    29101 cccgacggtt aaagagttta atttctttta aaccttcaat tgccccctgc gcgccaattg
    29161 ccgttgaggc accaccggcc cctaacagca ccatcgtttt gcctttgata tcaaaaccgc
    29221 tctctttaat ggcgcgaata tggcccgtgc cgtcggtgtt atagccacgc agatagccat
    29281 catcattaac gatggtgttg atggccccca ccagtttggc agctggtgtt aattcatcaa
    29341 catattcaca cgccagttgt ttgttcggca tcgatacacc agttccgcgc attttgaggg
    29401 cttttaatcc ttcaattgct ccaggaaagc tatcgttatc cacttcgaag gccatatagg
    29461 taaatggcaa tcccgctttt tctaaggctt tattctgcat ttcgggcgat aaactgtggc
    29521 ggataggata ggccatcaac ccaatcaatt cgtattttgc ggtaacatcc ataattaact
    29581 cctttaacct ctatgcttaa ttgtgtttaa ccgggtgcaa aatttacgct cgccaaaccg
    29641 cacatcattt tcaggaataa tgaaaacgcg gtaatagcgg ataaaaacaa taattgcggt
    29701 aatcagggcc agcagcgcga aagtaaaatc gagaacaatg atatattgca ggccgatgtt
    29761 cgacagataa ccggtaatca gtggaataac aaagttagcc agtccaccca tcatcatata
    29821 aatactggtg actttggctt tgcttttggg aaaaaactct gacatgaccg aaacgccgag
    29881 ctgtaaaatg ccgccagctg ctgagaaacc gataacaaag gctccggcat tgcacaccag
    29941 tggagaaggg tacaggtaga taatggctgc tgttattgtt gccagtgcag agttaaatac
    30001 attagcccag atgggccgga ccattttttt cagtagtgcg gcaaaaataa agacacagac
    30061 caacgagccc atactgtaat aagagatggt ttttaatgcc tcagcttctg acataccagc
    30121 aaaagccatc gcatatttgg gcatccacac cacaatcaca taaaaggtcg agaatgcggc
    30181 tacaccgaac agtaccgatg aaacaccttc cagccagact aacggtttgc tgttcatttg
    30241 cggtaattca ttagttacgc tggcgtccac caactggctg gggaatttgc ttttcaacag
    30301 catcagcgtg atcagtacaa atagaatacc cggaataatc agcccatagc cgtaccagat
    30361 attattgagc aacatatagc tcaccagcat tgggtagaac atttgcccaa atgacaccat
    30421 cgctttaacc agtatgaccg ccgaaccaga ggctttcgga aagcattcca tgagcgcggg
    30481 gtagccaccc gtatccagcg ctgagttagc gatacctacg cacactgcca gaccgtaggc
    30541 gagagttaaa ttcgggcaag cgggaatacc aaagaagaat agcagataca ttattactgc
    30601 cattaatatc accgcccgac gaccaaactt atcggagatc acaccgaaga ataaaatact
    30661 gatcaatcgc cccaaaccga taccggaaat taagtaggca atgcccgcgt tgtcagtgga
    30721 aaacttttcc gccagagatg acatattttg ggcaagcgta ataacactaa tgccgtgcag
    30781 gaagtagctg aagtaaatac aaagaacagc caggataaat ggcgtgctga aagccttatt
    30841 ttgagacatt ttcacagctc cttgctgaaa gataatttcg ttaccgtacg tattgttctc
    30901 cgacggttta cataattact atactgaaga tgattttccc tgggtacatg gcataaagtt
    30961 tatgtttcca ggaatattgc atgtcatagt ttgtttttga tcgcgatttt ccttagttag
    31021 cgcagaaaga gttatttatc cgtaagatct tgcatgacct gaaaagaata ttgcattacc
    31081 cacccggagc gacattttcc tttagcgagt gatgccgcgt ttttttgcgg ctgcgtaagc
    31141 cgataaacag tgccagtaaa aaaccgatgg cagcgatggc ggtatcgaac cacataatat
    31201 cggcaatact tctttgggac agatgagccg taatcaacgg aatagtaaag gtcgcaatac
    31261 tgcccgcact gtaatagatc cctgtagctt tacctttagc gtaagggaaa cgttcagcca
    31321 ttaacgtcag gccaatttgc acaacacctc cagcagaggt aaaaccaatg acaaaagcaa
    31381 atattatcac cacataaaat gtgggatgca ggcagacggt aaacagagca ataaatgaga
    31441 taaaggtgta cagcatcagt aatgttgttg ggcgaacggt attacgaatg agtggagcgg
    31501 taataaatac acaaagcagc gaacccacgg tgtagatact gagtagtttg atcgacatag
    31561 tgtatgacat gcctgcaaca aattgtccgt actgtgccag ccactggcta accagataaa
    31621 acgttgccat tgagatatag ccatataagg tataactggc taaatcgata attgaacagc
    31681 gatgttccgt agagctggtg gttttcttta tgacaggtaa gcgacgaccc ggatggggtg
    31741 ggaacgtaca acggtataaa aacagagcgt taataaacat aatgcctgca gcaatcataa
    31801 aggaccaacc gaaccacagt tcagcccaca ctaacaggct aatgattagc ggtaataaaa
    31861 attgtccgct ggaaacaaat gctttaatta aaatattggc tgtcccaggt gagcgtggaa
    31921 aagcttccat caaactggga taagtgcctg catcgagaaa actgtttgcc attcccgcca
    31981 gaaagccaaa aacataagcg ataatgatgt tattggtctg caggatgcca aaaaagaagg
    32041 ccatatagca gcacatcccg agcatgataa aagggcggcg accaaagcga tcggataata
    32101 atcctgcaaa aagcaagaca cttaatcgac caatgcccag cgatgagata actatcgaga
    32161 cacccgcggc attagtctgc caaagtgtct ccagcgaggc catattcagg ctcatcaaaa
    32221 ggacgcccat accatgcacc aggtaattaa aatacaaccc aagtgcggta gggaaatagg
    32281 gatttttcat aggttctact tagcaaaggt gctttaaaaa gtgaagcgat gttgtgtcag
    32341 catccgttca ttattgttgt aacaacgaca attcctttct gtggaaaaat taacaaagcc
    32401 gctccagatc gtgtgcatat aattcagcag ctaccgattg atagatcttc cagtcaataa
    32461 aattgccatc agggtagact cgttgaaatg cggttaagtc ggggaaaaaa cgcatggtgt
    32521 tgttgccgat gcggttattt attttctcta tgatggcatg aagatgtttt tttctttgct
    32581 gacgcatagc caacagttgc tcgactacac gatcaggaat ggcacacttg ccattttccc
    32641 actgacgcca gctttcactg tcaccggtct gggcaatcca ggtcgcgcat tcatcaatag
    32701 tcatggcaaa aatatggcgg agtgcctgga gttcataagc gttcatcgtg taatggctgc
    32761 atgaaataaa caataaaata taaataacat tatcagcctg ctgacggctt gaagagagtc
    32821 acagtatctt gtgcaacatt attagaaaga gtgaggggcg aggtagcgaa gcggaaaaat
    32881 gttaaaaaaa agcccatcgt gggagatggg caaagactac acacagcaat tcgttgtttc
    32941 actcagggga tttccatgct tataaatcaa tatgttgatt tataaccgtg agctaatagt
    33001 aggcatacgg actttttgcg tcgatcagat tcgtctcatt agtttaaaaa ctgtaaagaa
    33061 tttgcgacag gtactaccag ctgaatggcg gtaagcagga aaatatgggg aagagcaagc
    33121 aaatatcaat tagcggtggt taacaatcag gcggcagagc cgcctgatga gaaattactt
    33181 attcggtttc tcgatttcgc caagttcttc gagaatttct tccggttggt ccgtcggcgg
    33241 cgggacttct tccacccacg cggcaaacag acgccaggaa acggctaaca gaaccggacc
    33301 aataaacaga ccgatcatcc cgaaagcaat caaaccacca ataacgccag agagaatcag
    33361 gatcagcggt aaatcggcac ccatgcgaat taacattggg cggatgacgt tatccagcgt
    33421 gccaaccaca ccgctccaca ctaacaatac cgttccccag gtggtatcgc cagtccagta
    33481 gagccagata atcgccggaa tcagtaccgg caacgggcca agctggacaa ggcaggagag
    33541 gatcattaac accgttagca acgttgcata aggtacgccg gatacggcga ggccgatacc
    33601 gccaagcact gcctgtacta acgccgtcac caccacaccc agcgccaccg cgcggatagc
    33661 ctgtgccgcc agcagcacgg cggcatctcc gcgaacgcct gccagacggg ttgcaaaatg
    33721 gcgaatgcct tgtgccacct gttcaccgcg ccagtacagc agggcactga agagaagcat
    33781 cagcgcacaa tgcaccataa agcgcccgat atgcgccgcc tgcccaacga accaggtggt
    33841 ggtggtgcca atataagggc ggactttcgc catgatcgcc gtccccccca tatccagcaa
    33901 gttgtgccag cctgcataca gcttcgcgcc aatcaccgga atggtattaa gccacgccag
    33961 atcgggtaac gtcatgtcac cgctggaaat ggctttaatt agcgggccgc tgccgtcgac
    34021 gatactgtta accagcaaag caatagggat gataaacacc atcactaata acagcgtcat
    34081 caccagaacg gcgagagagc ggcggccaaa catgatcttt tgcaaacgta acaataccgg
    34141 ccaggtggcg ataaccaccg taccggccca tgcaaagccg agaataaagg gttgaacaat
    34201 ccacagacat gccacaatca tgatggctaa aaacagcacc gaaagcagaa tttgtgcgac
    34261 atccctgggc tgacgaacat ttaccataac tacttttcac cttttttgtg cgtcaaatcg
    34321 tcgacgcgac gtgaacacgc gaaactcacc tgcataatga tgagcaattt cagcggtttt
    34381 taacaggccg attctgccct taattctgat gggcgtgtta gaaaaaaatg tggtacaaca
    34441 actcaggcaa cacgcaaacg atttactcgt cgtatttcaa gttgcatgtg ctgcggctac
    34501 gttcgttcac cccagtcact tactattgta agctcctgga gttcactcgc ttgccgcctt
    34561 cctgcaacac gaaatccata gcgtaaacaa acatcacctt tcagtgcgct attgcagcag
    34621 cctgaaagaa tagtgtatcg acctacatca cagaccgcag gaaagggtca atataatgat
    34681 tccacagatt tcccaggcac ccggcgtcgt tcaactggtg cttaattttt tgcaagagct
    34741 ggagcaacaa ggttttaccg gcgatacggc gacaagttat gccgatcgtc tgacaatgtc
    34801 gaccgacaac agtatttacc aacttctccc cgatgcggtg gtatttccgc gttcaaccgc
    34861 agatgtggcg ctgatcgccc gtcttgccgc gcaggaacgc tattcatcgc tgatctttac
    34921 cccccgcggc ggcggcaccg gcactaacgg tcaggcgctc aaccagggga ttattgttga
    34981 tatgtcccgc catatgaacc gcatcatcga aattaaccct gaagagggct gggtgcgcgt
    35041 tgaggccggg gtgataaaag atcaactcaa tcagtacctg aaaccgttcg gctacttttt
    35101 tgcgccggaa ctttcgacca gcaaccgggc aacgctcggt gggatgatca ataccgatgc
    35161 atccggtcag ggatcgctgg tctatggcaa aacgtcagat cacgtacttg gcgtacgcgc
    35221 ggtgttgttg gggggcgata ttctcgatac gcaaccttta cccgtcgaat tggcggaaac
    35281 gctgggtaaa tccaatacca caatcgggcg aatttataac acggtttatc aacgttgccg
    35341 tcagcaacgc cagttaatta tcgacaactt ccccaaactt aaccgctttc ttaccggtta
    35401 cgatctgcgt catgtcttta acgatgagat gaccgagttc gacctgacgc gcattctgac
    35461 gggttcagaa gggacgctgg cctttattac cgaagcgcgg ctggatatta cacgcttgcc
    35521 taaagtgcgc cgtctggtga acgtcaaata tgactctttt gactctgcgc tgcgtaacgc
    35581 gccgtttatg gttgaggcgc gggcgctttc ggtagagacg gtggactcaa aagtgctgaa
    35641 tctggcgcgg gaagatattg tctggcattc cgtcagcgag ttgattaccg atgtgcctga
    35701 ccaagagatg ctcgggctga acattgtgga atttgctggt gatgatgagg cgctgattga
    35761 tgagcgggta aatgcactct gtgcgcggtt ggatgagctg atcgccagtc atcaagcagg
    35821 tgtcatcggc tggcaggtgt gccgtgagct ggcgggggtt gaacgtatct atgcaatgcg
    35881 caaaaaagcc gttggtctgc ttggcaatgc caaaggtgcc gctaagccaa ttccgtttgc
    35941 tgaggatacc tgcgtaccgc cggaacacct ggcggattat attgctgaat ttcgcgcgct
    36001 gctcgacagc cacggcttaa gctacggtat gttcggtcac gtcgacgcag gtgtcttgca
    36061 cgtccgtcca gcgctggata tgtgcgatcc tcaacaagag attttgatga agcaaatctc
    36121 tgatgacgtg gtggcgctga ctgcgaaata cggtggtttg ttgtggggcg agcacggcaa
    36181 aggttttcgc gctgaataca gcccggcgtt tttcggtgag gaactttttg cagaactgcg
    36241 caaagtgaaa gcggcatttg acccgcataa ccgactcaac ccagggaaga tttgcccgcc
    36301 agaaggtctc gatgcgccga tgatgaaagt ggacgcggtg aagcgcggta cattcgatcg
    36361 gcagatcccc attgcggtac gccagcagtg gcgcggtgcg atggagtgta acggcaacgg
    36421 tttatgcttc aactttgatg cccgtagtcc gatgtgtccg tcgatgaaga tcacccagaa
    36481 ccggattcat tcaccgaaag ggcgcgcaac gctggtgcgt gaatggctgc gtttgttggc
    36541 ggatcgcggc gttgatccac tcaaactgga acaagaactg cctgaatccg gcgtcagttt
    36601 gcggacgtta attgcccgca cgcgcaatag ctggcatgcg aataaaggcg aatatgactt
    36661 ctcacacgaa gtcaaagagg cgatgtcggg ctgtctggcc tgtaaagcgt gttcgaccca
    36721 gtgccccatc aaaattgatg tgccggagtt tcgctctcgt tttctgcagc tctatcacac
    36781 ccgttattta cgcccgctgc gcgaccacct cgtcgctacg gtcgagagct acgcgccgct
    36841 gatggcacgc gcgccgaaaa cctttaactt cttcattaac cagccgctgg tgcgcaaact
    36901 ctcggaaaaa catatcggca tggttgattt gccgctgctg tcggtcccct cgctacaaca
    36961 acaaatggtg gggcatcgct cggcaaacat gacgctggaa cagcttgaat ctctcaatgc
    37021 agagcagaaa gcgcgcacag tgttggtggt gcaggacccc tttaccagct attacgatgc
    37081 gcaagtggtg gcggattttg tccgtctggt cgaaaaatta ggtttccagc ctgtgttact
    37141 gccattttcg ccaaatggca aagcccagca tattaaaggt tttcttaatc gttttgcgaa
    37201 gacggcgaaa aagacggcgg atttcctcaa ccgtatggcg aagctgggta tgccaatggt
    37261 gggcgtcgat ccggcgctgg tactttgtta tcgcgatgaa tataaactgg cgctgggcga
    37321 ggagcgtggc gagtttaacg tcttactggc gaatgaatgg ctggcaagcg cacttgagtc
    37381 acagccagtg gctacagtca gcggtgaatc atggtatttc tttggtcact gtaccgaagt
    37441 taccgccttg ccgggtgcgc cagcacaatg ggccgcgata tttgcccgtt ttggcgcgaa
    37501 actggaaaat gtcagcgtgg gttgctgcgg catggcaggg acttacggac atgaagcgaa
    37561 aaaccatgaa aattcgctcg ggatctatga gttatcctgg catcaggcta tgcagcgact
    37621 gccgcgtaac cgctgtctgg cgaccggata ttcctgccgt agccaggtaa aacgggttga
    37681 aggcacgggg gtacgccatc ctgtgcaggc tttactggag attattaaat gatatggaaa
    37741 cggaaaatca ccctggaagc actgaatgct atgggtgaag gaaacatggt ggggttcctg
    37801 gatattcgct ttgaacatat tggtgatgac acccttgaag cgacaatgcc agtagactcg
    37861 cggacaaagc agcctttcgg gttgctgcat ggaggagcat ccgtggtact ggccgaaagt
    37921 atcggttccg ttgccggtta tttatgtacc gaaggtgagc aaaaagtggt tggtctggaa
    37981 atcaatgcta accacgtccg ctcggcacga gaagggcggg tgcgcggcgt atgcaaaccg
    38041 ttgcatctcg gttcgcgtca ccaggtctgg cagattgaaa tcttcgatga gaaagggcgt
    38101 ttgtgctgtt cgtcacgatt gacgaccgcc attttgtgac gttgtcacca gaaaagtgtg
    38161 acgcatattg cttttggtca ttatctgcac agtaaacggt ggtatactgt gcaggtcttg
    38221 tctaaaagcg aggatgctat gtctactcaa cttgatccca cccagctggc cattgaattt
    38281 ttacgccgtg accagagcaa tctttcacct gcccaatatc tcaaacgtct gaaacaacta
    38341 gaacttgaat ttgctgacct gcttactctc tcttctgctg aattaaaaga agaaatctac
    38401 tttgcctggc gtctgggcgt gcattgatcc tgacttaatg ccgcaagttc gccaaatcga
    38461 cctggattaa cctccgtcca ggttcgatga ccttcttaat actgcttatc taccgcctga
    38521 tattgttcaa aaataatact aatcgcagtt tgtgttaaaa cggcgggtta gctttatgag
    38581 attattctta tcgccccttc aagagctaag ccactgagag tgccggagat aagcgccgga
    38641 tggggtagaa acccttaagc ctgtgtcgca cagacttaag ggttttctta tttctgaacg
    38701 ctgcactttt ttacctatct cttaaatagt cattttcaat acaacttttt ctttttcatc
    38761 acagccttaa tgctccttag ataataacca ttatctaaca atgagatacc taattcttag
    38821 cgtgcctgtt aacccacaca tcagggtcta tgcttattaa aagcaggcaa aaagcatgtt
    38881 ttacggtaaa gcccctgcgt ttgctgggtt gaactgataa tcattatcac taacatgctg
    38941 ttatacgctg aaagcgatga agtgaggtaa atcgatggac atgcattcag gaacctttaa
    39001 cccacaagat ttcgcctggc aaggcttaac gctgacaccc gcagcggcga tacacatccg
    39061 tgagctggtg gcaaagcagc cgggtatggt cggcgtgcgc ttaggcgtga agcaaacggg
    39121 ctgcgcgggc tttggctatg tgctcgacag tgttagcgag ccggacaaag acgatctgct
    39181 gtttgaacac gacggcgcga agctgtttgt cccgctgcaa gcgatgccgt ttattgatgg
    39241 cacggaagtc gatttcgttc gtgaaggact taatcagata ttcaaatttc acaaccctaa
    39301 agcccagaat gaatgtggct gtggcgaaag ctttggggta taggcggtac tatgtctcgt
    39361 aatactgaag caactgacga tgtcaaaacc tggaccggcg gcccgctgaa ttataaagaa
    39421 ggattcttca cccagttagc caccgatgag ctggcaaagg ggataaacga agaggtggtg
    39481 cgcgcaattt cggcgaagcg taatgagccg gagtggatgc tggagtttcg tctaaacgcc
    39541 tatcgcgcat ggctggagat ggaagaaccg cactggttga aagcgcacta cgacaagctg
    39601 aattatcagg attacagcta ctactcagca ccatcgtgcg gtaattgtga cgacacttgc
    39661 gcgtctgaac ctggcgcggt gcagcaaact ggcgcgaacg cctttttaag taaagaggtg
    39721 gaggcggcgt ttgagcagtt gggcgttccc gtgcgggaag gcaaagaggt ggcggtggat
    39781 gccattttcg actcagtttc ggttgccact acttatcgcg aaaaactggc ggagcaggga
    39841 attattttct gttcctttgg tgaggcgatc cacgatcacc cggaactggt gcgtaaatat
    39901 ctcggcaccg tggtgccggg gaatgacaac ttctttgccg cgcttaatgc ggcggtagcc
    39961 tctgacggta cgtttattta tgtgcctaaa ggcgtgcgct gcccgatgga actttccacc
    40021 tattttcgca ttaacgcaga aaaaaccggg cagtttgagc gcaccattct ggtggccgac
    40081 gaagacagct acgtcagcta cattgaaggc tgttccgctc cggtgcgtga cagctatcag
    40141 ttacacgcgg cagtggtgga agtcatcatc cataaaaacg ccgaggtgaa atattccacg
    40201 gtacaaaact ggtttcctgg cgataacaac accggcggta ttctcaactt cgtcaccaag
    40261 cgtgctttgt gcgaaggcga aaacagcaaa atgtcatgga cgcaatcaga aaccgggtca
    40321 gcgattacgt ggaaatatcc cagctgcatt ttgcgcggcg ataactccat tggtgagttt
    40381 tactcagtgg cgctgaccag cggtcatcag caagcggata ccggcaccaa gatgatccac
    40441 atcggtaaaa acaccaaatc gaccattatc tcgaaaggga tctctgccgg acatagtcag
    40501 aacagttatc gcggcttagt gaaaatcatg ccgacggcaa ccaatgcgcg caatttcact
    40561 cagtgcgact caatgctgat tggcgctaat tgtggggcgc ataccttccc gtatgttgag
    40621 tgtcgtaaca atagagcgca actggaacac gaggcaacga catcacgtat tggtgaagat
    40681 caactgtttt actgcctgca acgcgggatc agcgaagaag acgccatctc gatgattgtt
    40741 aacggtttct gcaaagacgt gttctcggag ctgccgttgg aatttgccgt tgaagcacaa
    40801 aaactcctcg ccatcagtct tgaacacagc gtcggataag gaataaacat gttaagtatt
    40861 aaagatttac acgtcagcgt ggaagataaa gctatcctgc gcggattaag cctcgacgtt
    40921 catcccggcg aagttcacgc cattatgggg ccaaacggtt cgggcaaaag taccttatcg
    40981 gcaacgcttg ccgggcgaga agattatgaa gtgacgggcg gcacggttga gttcaaaggc
    41041 aaagatttgc ttgcgctgtc gccggaagat cgcgcgggcg aaggcatctt tatggccttc
    41101 cagtatccgg tggagattcc aggtgtcagt aaccagtttt tcctgcaaac ggcacttaat
    41161 gcggtgcgca gctatcgcgg ccaggaaacg ctcgaccgct ttgattttca ggatttgatg
    41221 gaagagaaaa tcgctctcct gaagatgccg gaagatttat taacccgttc ggtaaacgtt
    41281 ggtttttccg gcggcgagaa aaagcgcaac gatattttgc aaatggcggt gctggaaccg
    41341 gagttatgca ttcttgatga gtcggactcc gggctggata ttgacgcatt aaaagtggtc
    41401 gccgatggcg tgaactcgct gcgtgatggc aagcgctcat tcatcattgt tacgcactac
    41461 caacgcattc tcgactacat caagccttat tacgttcatg tgctatatca gggacgaatt
    41521 gtgaaatccg gcgatttcac gttggtcaaa caactggagg agcagggtta tggctggctt
    41581 accgaacagc agtaacgcgc tgcaacagtg gcatcacttg tttgaagctg aagggacaaa
    41641 acgctccccg caagcacagc agcatttaca acaattgctg cgtaccggac tgccgacacg
    41701 taaacatgaa aactggaaat atacgccgct ggaagggctg atcaatagcc agtttgtcag
    41761 cattgcggga gagatatccc cacagcagcg tgatgcctta gcgttaacgt tagactccgt
    41821 gcggctggtg tttgtcgatg ggcgttacgt gcccgcactg agcgatgcaa ctgaaggcag
    41881 cggatatgaa gtgagcatta acgacgaccg tcagggttta cccgacgcta ttcaggcgga
    41941 agtgtttctg catttgacgg aaagcctggc acaaagcgtg acgcatatcg ccgtgaagcg
    42001 cggtcaacgg ccggcaaagc cattgctgtt aatgcatatc acccagggcg tggcaggtga
    42061 agaggtgaac actgcccatt accgacatca tctggatctg gcggaaggtg ccgaagcaac
    42121 ggtgatcgaa cattttgtca gcctgaatga tgctcgtcat tttaccgggg cacggttcac
    42181 tatcaacgtc gcagcgaatg cccacttgca gcatatcaag ctggcgtttg aaaacccgct
    42241 cagtcaccac tttgctcata acgatttgtt gctggctgag gatgccaccg catttagcca
    42301 cagtttcctg ctgggtggcg cagtgttacg acacaacacc agtacgcaac tcaatggcga
    42361 aaacagcacg ctgcggatca atagcctggc gatgccggtg aaaaacgagg tgtgtgatac
    42421 ccgtacctgg ctggaacaca ataaaggttt ttgtaacagc cgacagttgc acaaaactat
    42481 cgtcagcgac aaaggccgcg cggtatttaa cggtttgatc aacgtcgcgc agcacgccat
    42541 caaaacggat ggtcagatga ccaacaacaa tctgctgatg ggcaaactgg cggaagtgga
    42601 tacgaaaccg cagctggaaa tctatgcaga tgatgtgaaa tgcagccacg gcgcgacggt
    42661 ggggcgtatt gatgatgaac agatattcta tctgcgctcg cgcgggatca atcagcagga
    42721 tgcccagcag atgatcattt acgccttcgc tgccgaactg acggaagcac tgcgtgatga
    42781 ggggcttaaa cagcaggtgc tggcccgaat cggtcaacgg ctgccaggag gtgcaagatg
    42841 attttttccg tcgacaaagt gcgggccgac tttccggtgc tttcgcgtga ggtaaacggt
    42901 ttgccgctgg cttatctcga cagcgccgcc agtgcgcaga aaccgagcca ggtgattgac
    42961 gccgaggccg agttttatcg tcatggctac gcggcggtgc atcgtggtat tcatacctta
    43021 agcgcccagg cgaccgagaa aatggagaac gtgcgcaagc gggcatcgct gtttattaat
    43081 gcccgttcgg cggaagagct ggtgttcgtc cgcggcacga cggaagggat caatctggtc
    43141 gccaatagct ggggcaacag caacgtgcgg gcgggcgata acatcatcat cagtcagatg
    43201 gagcaccacg ctaacattgt tccctggcag atgctttgcg cacgcgttgg cgcagagctg
    43261 cgtgtgatcc cgctcaatcc cgatggtacg ttgcaactgg agacgctgcc tacgctgttt
    43321 gatgagaaaa ctcgcctgct ggcaattact catgtctcca acgtgcttgg cacagaaaat
    43381 ccactggcgg aaatgatcac gcttgcgcac cagcatggcg caaaagtgct ggtggatggc
    43441 gctcaggcgg tgatgcatca tccggtggat gttcaggcgc tggattgcga cttttacgtg
    43501 ttctccgggc ataaactgta tggccccacc ggaattggca ttctttatgt gaaagaagcc
    43561 ttgttgcagg agatgccgcc gtgggaaggg ggcggttcta tgatcgccac cgtcagcctg
    43621 agtgaaggca ctacctggac caaagcacca tggcggtttg aagccggtac acccaatacc
    43681 gggggcatca ttggtcttgg cgcggcgctg gagtatgttt cggcgctggg gcttaataac
    43741 atagccgagt atgaacagaa tctgatgcat tatgcgctat cacagctgga atctgtaccg
    43801 gatctcactc tctatggccc acaaaacagg cttggcgtta ttgcttttaa tctcggtaaa
    43861 caccacgcct atgatgttgg cagttttctc gataattacg gcattgctgt gcgtaccgga
    43921 catcactgcg caatgccatt gatggcctat tacaacgtcc ctgcgatgtg tcgggcgtcg
    43981 ctggccatgt ataacaccca tgaagaagtg gatcgtctgg tgaccggcct gcaacgtatt
    44041 caccgtttgc tgggataaca gggaggcact atggctttat tgccggataa agaaaagttg
    44101 ctgcgtaatt ttttacgctg cgccaactgg gaagagaaat atctctacat tattgagctg
    44161 ggccagcgtc tgccagaatt acgcgacgaa gacagaagtc cacaaaatag cattcagggc
    44221 tgtcagagtc aggtgtggat tgtcatgcgc cagaatgccc agggaattat tgaattacag
    44281 ggcgacagcg atgcggcgat tgtgaaaggg cttattgcgg tcgtctttat tctctacgat
    44341 cagatgacgc cgcaggatat tgtcaatttc gatgtgcgtc cgtggtttga aaaaatggcg
    44401 ctcacccaac atctcacccc atctcgttca caaggtctgg aagcgatgat tcgcgcaatt
    44461 cgcgccaaag ccgctgcact tagctaaact aaaaggacag ctttcatccg gttggctcac
    44521 attgccggat ggtcaatgtt tacactgacc tgcacaggag tgttttggtt tcaggtgaac
    44581 ataagcgcca tccgacgttt cagcgtgagt ctccggcaaa tacaggaggt ttacaatgaa
    44641 acgcgcgtct ttgcttacac tcacgcttat cggcgctttt agcgccatcc aggctgcctg
    44701 ggcggttgat tatccgctac caccaaccgg aagccgactg gttgggcaaa atcaaacgta
    44761 tacggtgcaa gaaggggata aaaaccttca ggctattgcc cgacgttttg atactgcggc
    44821 aatgttgatc cttgaagcca ataacactat cgccccggtg ccaaaacctg gtacgacgat
    44881 aactattcct tcacaactgt tattacctga tgcaccgcgt caggggatta tcgttaacct
    44941 tgcagagctg cgcctttatt attatccgcc gggagaaaat attgtgcagg tttatccaat
    45001 aggtattgga ttgcaggggc tggaaacgcc ggtgatggaa acgcgtgttg ggcagaaaat
    45061 ccctaaccca acctggacgc ctacggcagg cattcgtcag cgttcgctgg agcgtggcat
    45121 taaattaccg ccagtcgttc ctgccggacc aaataacccg ctaggacgtt acgcactgcg
    45181 cctcgcgcat ggtaatggcg aatacctcat tcatggtacc agtgcgccgg acagcgtcgg
    45241 tttgcgcgtc agttcagggt gtattcgcat gaatgcaccg gatattaaag ccttgttctc
    45301 cagcgtgcgg acgggaacgc cggtgaaagt gatcaacgaa ccggtgaaat attccgtgga
    45361 gcctaacggg atgcgttatg ttgaagtaca tcgaccacta tcggcagaag aacagcagaa
    45421 cgttcagaca atgccataca cactgccagc aggctttacg caatttaaag acaataaggc
    45481 tgtagatcag aagttagtcg ataaagcgtt gtatcgtcgg gcagggtatc cggtttcggt
    45541 gagcagtgga gcaactcccg cagccagcaa tgcgccttca gtagagtcag cgcagaatgg
    45601 tgaaccagag caagggaata tgttacgcgt gacgcagtag cggtaaacgg cagacaaaaa
    45661 aaatggcgca caatgtgcgc catttttcac ttcacaggta ctattacttg cggtatttag
    45721 tagccatgtt gtccagacgc tggttagcac gagctgcgtc atctttagca gcctgaacgt
    45781 cggaacgcat tgcgttcacg tcgttgctca gctggtcaac tttagcgttc agagtctgaa
    45841 cgtcagaaga cagctgatcg attttagcgt tgctggagca acctgccagc agagtagaac
    45901 ccaggattac cgcgcccagt accagtttag tagctttcat tattaatacc ctctagattg
    45961 agttaatctc catgtagcgt tacaagtatt acacaaagtt ttttatgttg agaatatttt
    46021 tttgatggga aggcacttat ttttgatcgt tcgctcaaag aagcatcgaa cgctgggttt
    46081 tagataaaaa aattgagaga aaacaggatg cttccatcgg attcatctta gataaagtga
    46141 gattatatag tgaaatccga tttgattttt tattgcttct ggttatcgat taaataaaaa
    46201 aagcgcccat cagggcgctt cgatatacaa attaattcac aaaagcaata ttacaggacg
    46261 tgaacagatg cggtgttagt agtgccgctc ggtaccagtg caccagaaac cataactaca
    46321 acgtcacctt tgtgtgccag accgctctgc agagccagtt ctttacccag acggtagaaa
    46381 tcatcagtag aagtgatctc tttaacaagc tgcggcacaa cgcctttgct cagtaccaac
    46441 tgatgagccg ttttttcgtt ggtggtcagt gccaggatgg tggcatccgg gaagtattta
    46501 cgtactgcgc gagcagattt accgccctga gtagcaacca cgatcagcgg agcatccagt
    46561 ttttcagcag tttcaacggc accacggcat accgcttcgg taatgcgcag tttacggttg
    46621 tcattgttga actcgagacg gctgttcatc acgcggtcgg tacgttcgca gatggtcgcc
    46681 atgatagaaa ccgcttccag cgggtattta ccttttgcgg attcaccaga cagcatcact
    46741 gcgtcagtac cgtcgaggat ggcgtttgca acgtcaccgg cttctgcgcg agtcgggcgt
    46801 gggtttttga tcatggaatc cagcatctgg gtcgcagtga taacgacttt acgtgcacgg
    46861 atacattttt cgatcatcat cttctgggcg aagataactt cttctaccgg gatttctaca
    46921 cccaggtcgc cacgcgcaac catgatgccg tcagaggctt cgaggatttc gtcgaagttg
    46981 ttgaggcctt cctggttttc gattttggag atgatgtgga tgttttcgcc gccgtgcgct
    47041 ttcaggtgct cacggatttc gataacgtca gaacgcttac gaataaagga agcagcaaca
    47101 aagtctacgc cttgttcgca accaaagatc aggtcctgtt tgtctttttc agccagtgct
    47161 ggcagagcaa tggaaacgcc aggcaggttc acacctttgt tttcgcccag gtcaccgttg
    47221 ttcagcactt tacagataac tttgttacct tcaatggcgg taacttccat accgatcaga
    47281 ccatcgtcaa ccagtacggt gttgccaaca gacaggtcag tagtgaaacc ttcatacgtt
    47341 accgcaacca tttcgctgtt gccgataaca gatttatcag tggtgaaagt aaaggtctga
    47401 ccagctttca gagaaacgtc gttaccgcct tccagtttca tggtgcggat ttccggacct
    47461 ttggtatcaa gcaggatagc ggcggtttta ccagttttgc tcatcacgtt gcgcagattc
    47521 tgaatgcgct gaccgtgttc tgcatagtca ccatgagaga agttcagacg cataacgttc
    47581 atgccagcgt ccagcatttt agctaacatc tcttcagatt cggttttcgg tccgatggtg
    47641 caaacaattt tggtcttttt catgacagtc ttagtcttta agttgagaag gatgggagaa
    47701 acttgctttc tgggcgcact gccggaaagc gaatccggta ttacgaaagt ggtggtgcct
    47761 cgctctaagg ataggtgaca tcgaaaaagc gtgcagagga atgtgtgctt gtgtctcagc
    47821 ccaacgtgag tgcctgtttt tgagtcgttg agttctacag tccaaagtgc tgaaaccatt
    47881 caagagtcaa ttggcgcgca ttatacgctg aaattaatcc aaaaggaaaa caaaaacagc
    47941 gtttcaaaaa atatacaact tgttagacaa taaattgtta tcaaagattt aacgttccag
    48001 ggaaaaggtt acgcaaaaac ttcactgttt gcgcaacgtc tggtgccgaa gttgtcagtg
    48061 tgaggataag tgaaagttca tccggtgtat aaatatatca tcgctcaatt gctacagtta
    48121 aaataattta tcgcgttatt tgtctgattt tgtttgattt ttgtttaatt ggttagattg
    48181 atatatgctg atagttggca tgataaatag gtataaagaa tgggaaatcg gacaaaagag
    48241 gatgaactgt accgagaaat gtgcagagtt gtcggtaaag ttgtgctgga aatgcgcgat
    48301 ctggggcagg aaccaaagca tattgttatc gcaggcgtat tacgtacagc attagccaat
    48361 aaacgcattc agcgcagtga gctggaaaag caggcgatgg aaaccgtcat taacgcactg
    48421 gtaaaatgac cattcaggat gaggcggtaa gcttcatcct gatattcttg cttcagttgc
    48481 ggtcca
//
LOCUS       DAPOAV010000027        48301 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.027, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000027 DAPOAV010000000
VERSION     DAPOAV010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 48301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48301
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.027"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            180..1397
                     /gene="alaA"
                     /locus_tag="RN951_001792"
     CDS             180..1397
                     /gene="alaA"
                     /locus_tag="RN951_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase AlaA"
                     /protein_id="HDX2526800.1"
                     /translation="MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPA
                     PFGFDAPDEILVDVIRNLPTAQGYCDSKGLYSARKAIMQHYQARGMRDVTVEDIYIGN
                     GVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDD
                     IRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIFADEIYDKILYDDA
                     EHHSIAPLAPDLLTITFNGLSKTYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRL
                     CANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRAWELINDIPGVSCVKPRGALYM
                     FPKIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHFRIVTLPRVDDIELSL
                     SKFARFLSGYHQL"
     gene            1481..2080
                     /gene="yfbR"
                     /locus_tag="RN951_001793"
     CDS             1481..2080
                     /gene="yfbR"
                     /locus_tag="RN951_001793"
                     /EC_number="3.1.3.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-deoxynucleotidase"
                     /protein_id="HDX2526801.1"
                     /translation="MKQSHFFAHLSRLKLINRWPLMRNVLTENVSEHSLQVAMVAHAL
                     AAIKNRKFGGNVNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQ
                     KLVDMVPEELRDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFLLAK
                     TRLEATLESRRSQEMDYFMEVFVPSFHLSLDEISQDSPL"
     gene            complement(2139..3971)
                     /locus_tag="RN951_001794"
     CDS             complement(2139..3971)
                     /locus_tag="RN951_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HDX2526802.1"
                     /translation="MNGELIWVLSLLAVAIVLFATGRVRMDAVALFVIVAFALSGTLT
                     VPEVFSGFSDPNVVLIAALFIIGDGLVRTGVATVMGTWLVKVAGNSEIKMLVLLMLTV
                     AGLGAFMSSTGVVAIFIPVVLSVAMRMQTSPSRLMMPLSFAGLISGMMTLVATPPNLV
                     VNSELLREGYHGFSFFSVTPIGLVVLVLGILYMLVMRFMLKGDTQTPQREGWTRRTFR
                     DLIREYRLTGRARRLAIRPGSPMIGQRLDDLKLRERYGANVIGVERWRRFRRVIVNVN
                     GVSEFRARDVLLIDMSAADVDLRQFCSEQLLEPMVLRGEYFSDQALDVGMAEISLIPE
                     SELIGKSVREIGFRTRYGLNVVGLKRNGVALEGSLADEPLLLGDIILVVGNWKLIGML
                     AKQGRDFVALNLPEEVSEASPAHSQAPHAIFCLVLMVALMLTDEIPNPVAAIIACLLM
                     GKFRCIDAESAYKSIHWPSIILIVGMMPFAVALQKTGGVALAVKGLMDIGGGYGPHMM
                     LGCLFVLSAVIGLFISNTATAVLMAPIALAAAKTMGVSPYPFAMVVAMAASAAFMTPV
                     SSPVNTLVLGPGNYSFSDFVKLGVPFTIIVMAVCVVMIPMLFPF"
     gene            complement(4058..4708)
                     /gene="hxpA"
                     /locus_tag="RN951_001795"
     CDS             complement(4058..4708)
                     /gene="hxpA"
                     /locus_tag="RN951_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexitol phosphatase HxpA"
                     /protein_id="HDX2526803.1"
                     /translation="MRCKGFLFDLDGTLVDSLPAVERAWSNWARRHGLAPEEVLAFIH
                     GKQAITSLRHFMAGKSEADIAAEFTRLEHIEATETEGITALPGAIALLNHLNKAGIPW
                     AIVTSGSMPVARARHKIAGLPAPEVFVTAERVKRGKPEPDAYLLGAQLLGLAPQECVV
                     VEDAPAGVLSGLAAGCHVIAVNAPADTPRLNEVDLVLHSLEQITVTKQPNGDVIIQ"
     gene            complement(4719..5213)
                     /locus_tag="RN951_001796"
     CDS             complement(4719..5213)
                     /locus_tag="RN951_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007371080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HDX2526804.1"
                     /translation="MEMTNAQRLILSNQYKMMTMLDPANAERYRRLQTIIERGYGLQM
                     RELDREFGELKEETCRTIIDIMEMYHALHVSWSNLQDQQSIDERRVTFLGFDAATEAR
                     YLGYVRFMVNVEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHACPRQYHLSANEINQ
                     IINA"
     gene            complement(5296..5751)
                     /locus_tag="RN951_001797"
     CDS             complement(5296..5751)
                     /locus_tag="RN951_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF412 domain-containing protein"
                     /protein_id="HDX2526805.1"
                     /translation="MSTPDNRSVNFFSLFRRGQHYSKTWPLEKRLAPVFVENRVIKMT
                     RYAIRFMPPIAVFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSVTPLPPAI
                     LNWFYEVRGKLQESGQVLAPVEGKPDYQALADTLKRAFKQLDKTFLDDL"
     gene            6089..7291
                     /gene="ackA"
                     /locus_tag="RN951_001798"
     CDS             6089..7291
                     /gene="ackA"
                     /locus_tag="RN951_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HDX2526806.1"
                     /translation="MSSKLVLVLNCGSSSLKFAIIDAVNGEEYLSGLAECFHLPEARI
                     KWKMDGNKQEAALGAGAAHSEALNFIVNTILAQKPELSAQLTAIGHRIVHGGEKYTSS
                     VVIDESVIQGIKDAASFAPLHNPAHLIGIEEALKSFPQLKDKNVAVFDTAFHQTMPEE
                     SYLYALPYNLYKEHGIRRYGAHGTSHFYVTQEAAKMLNKPVEELNIITCHLGNGGSVS
                     AIRNGKCVDTSMGLTPLEGLVMGTRSGDIDPAIIFHLHDTLGMSVDAINKLLTKESGL
                     LGLTEVTSDCRYVEDNYATKEDAKRAMDVYCHRLAKYIGAYTALMDGRLDAVVFTGGI
                     GENAAMVRELSLGKLGVLGFEVDHERNLAARFGKSGFINKEGTRPAVVIPTNEELVIA
                     QDASRLTA"
     gene            7366..9510
                     /gene="pta"
                     /locus_tag="RN951_001799"
     CDS             7366..9510
                     /gene="pta"
                     /locus_tag="RN951_001799"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HDX2526807.1"
                     /translation="MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPR
                     TGGDAPDQTTTIVRANSSTTTAAEPLKMSYVEGLLSSNQKDVLMEEIVANYHANTKDA
                     EVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLKERIELTRNSFG
                     GAKNTNITGVIVNKLNAPVDEQGRTRPDLSEIFDDSSKAKVNNVDPAKLQESSPLPVL
                     GAVPWSFDLIATRAIDMARHLNATIINEGDINTRRVKSVTFCARSIPHMLEHFRAGSL
                     LVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCERAFATGLPVFMVNT
                     NTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINADWIESLTATSERSRRLSPPAF
                     RYQLTELARKAGKRIVLPEGDEPRTVKAAAICAERGIATCVLLGNPAEINRVAASQGV
                     ELGAGIEIVDPEVVRESYVGRLVELRKNKGMTETVAREQLEDNVVLGTLMLEQDEVDG
                     LVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDPTAEQL
                     AEIAIQSADSAAAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGP
                     LQYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQG
                     MRKPVNDLSRGALVDDIVYTIALTAIQSAQQQ"
     gene            9700..11220
                     /gene="yfcC"
                     /locus_tag="RN951_001800"
     CDS             9700..11220
                     /gene="yfcC"
                     /locus_tag="RN951_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HDX2526808.1"
                     /translation="MSAITESKPTRRWAMPDTLVIIFFVAILTSLATWVVPVGMFDSQ
                     EVQYQVDGQTKTRKVVDPHSFRILTNEAGEPEYHRVQLFTTGDERPGLMNFPFEGLTS
                     GSKYGTAVGIIMFMLVIGGAFGIVMRTGTIDNGILALIRHTRGNEILFIPALFILFSL
                     GGAVFGMGEEAVAFAIIIAPLMVRLGYDSITTVLVTYIATQIGFASSWMNPFCVVVAQ
                     GIAGVPVLSGSGLRIVVWVIATLIGLIFTMVYASRVKKNPLLSRVHESDRFFREKQAD
                     VEQRPFTFGDWLVLIVLTAVMVWVIWGVIVNAWFIPEIASQFFTMGLVIGIIGVVFRL
                     NGMTVNTMASSFTEGARMMIAPALLVGFAKGILLLVGNGEAGDASVLNTILNSIANAI
                     SGLDNAVAAWFMLLFQAVFNFFVTSGSGQAALTMPLLAPLGDLVGVNRQVTVLAFQFG
                     DGFSHIIYPTSASLMATLGVCRVDFRNWLKVGATLLGLLFIMSSVVVIGAQLMGYH"
     gene            complement(11253..11795)
                     /gene="yfcD"
                     /locus_tag="RN951_001801"
     CDS             complement(11253..11795)
                     /gene="yfcD"
                     /locus_tag="RN951_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase YfcD"
                     /protein_id="HDX2526809.1"
                     /translation="MEQRRLASTEWVDIVNEENEVIAQASREQMRAQCLRHRATYIVV
                     HDGMGKILVQRRTETKDFLPGMLDATAGGVVQADEQLLESARREAEEELGIAGVPFAE
                     HGQFYFEDKNCRVWGALFSCVSHGPFALQEDEVSEVCWLTPEEITARCDEFTPDSLKA
                     LALWMKRNAKNEAVETETAE"
     gene            complement(11853..12404)
                     /gene="yfcE"
                     /locus_tag="RN951_001802"
     CDS             complement(11853..12404)
                     /gene="yfcE"
                     /locus_tag="RN951_001802"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311211.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HDX2526810.1"
                     /translation="MKLMFASDIHGSLPATERVLELFAQSGAQWLVILGDVLNHGPRN
                     ALPEGYAPAKVAERLNEVAHKVIAVRGNCDSEVDQMLLHFPITAPWQQVLLEKQRLFL
                     THGHLFGPENLPALNQNDVLVYGHTHLPVAEQRGEIFHFNPGSVSIPKGGNPASYGML
                     DNDVLSVIALNDQSIIAQVAINP"
     gene            complement(12460..13104)
                     /gene="yfcF"
                     /locus_tag="RN951_001803"
     CDS             complement(12460..13104)
                     /gene="yfcF"
                     /locus_tag="RN951_001803"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase"
                     /protein_id="HDX2526811.1"
                     /translation="MSKPAITLWSDAHFFSPYVLSAWVALQEKGLSFHIKTIDLDSGE
                     HLQPTWQGYGQTRRVPLLQIDDFELSESSAIAEYLEDRFAPPTWERIYPLDLENRARA
                     RQIQAWLRSDLMPIREERPTDVVFAGAKKAPLTAEGKASAEKLFAMAEHLLVLGQPNL
                     FGEWCIADTDLALMINRLVLHGDEVPERLVDYATFQWQRASVQRFIALSAKQSG"
     gene            13240..13887
                     /gene="yfcG"
                     /locus_tag="RN951_001804"
     CDS             13240..13887
                     /gene="yfcG"
                     /locus_tag="RN951_001804"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GSH-dependent disulfide bond oxidoreductase"
                     /protein_id="HDX2526812.1"
                     /translation="MIDLYFAPTPNGHKITLFLEEAELDYRLIKVDLGKGGQFRPEFL
                     RISPNNKIPAIVDHSPADGGEPLSLFESGAILLYLAEKTGLFLSHETRERAATLQWLF
                     WQVGGLGPMLGQNHHFNHAAPQTIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYS
                     IADIACWPWVNAWTRQRIDLAMYPAVKNWHERIRSRPATGQALLKAQLGDERSDS"
     gene            13944..14306
                     /gene="folX"
                     /locus_tag="RN951_001805"
     CDS             13944..14306
                     /gene="folX"
                     /locus_tag="RN951_001805"
                     /EC_number="5.1.99.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate 2'-epimerase"
                     /protein_id="HDX2526813.1"
                     /translation="MAQPAAIIRIKNLRLRTFIGIKEEEINNRQDIVINVTIHYPADK
                     ARTSEDINDALNYRTVTKNIIQHVENNRFSLLEKLTQDVLDIAREHHWVTYAEVEIDK
                     LHALRYADSVSMTLSWQR"
     gene            14327..15220
                     /locus_tag="RN951_001806"
     CDS             14327..15220
                     /locus_tag="RN951_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01777 family oxidoreductase"
                     /protein_id="HDX2526814.1"
                     /translation="MNIVITGGTGLIGRHLIPRLLELGHQITVVTRNPQKASSVLGPR
                     VTLWQGLAAQSNLNGVDAVINLAGEPIADKRWTHEQKERLCQSRWNITQKLVDLINAS
                     DTPPSVLISGSATGYYGDLGEVVVTEEEPPHNEFTHKLCARWEEIACRAQSDKTRVCL
                     LRTGVVLAPDGGILGKMLPPFRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLDNELRG
                     PFNMVSPYPVRNEQFAHALGHALHRPAILRVPATAIRLLMGESSVLVLGGQRALPKRL
                     EEAGFAFRWYDLEEALADVVR"
     gene            complement(15268..16158)
                     /gene="rpnB"
                     /locus_tag="RN951_001807"
     CDS             complement(15268..16158)
                     /gene="rpnB"
                     /locus_tag="RN951_001807"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-promoting nuclease RpnB"
                     /protein_id="HDX2526815.1"
                     /translation="MTISTTSTPHDAVFKSFLRHPDTARDFIDIHLPAPLRKLCDLTT
                     LKLEPNSFIDEDLRQYYSDLLWSVKTQEGVGYIYVVIEHQSKPEELMAFRMMRYSIAA
                     MQNHLDAGYKELPLVIPMLFYHGCRSPYPYSLCWLDEFAEPAIARKIYSSAFPLVDIT
                     VVPDDEIMQHRKMALLELIQKHIRQRDLLGLVDQIVSLLVTGNTNDRQLKALFNYVLQ
                     TGDAQRFRAFIGEIAERAPQEKEKLMTIADRLREEGAMQGKHEEALRIAQEMLDRGLD
                     RELVMMVTRLSPDDLIAQSH"
     gene            complement(16355..17128)
                     /gene="hisP"
                     /locus_tag="RN951_001808"
     CDS             complement(16355..17128)
                     /gene="hisP"
                     /locus_tag="RN951_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter ATP-binding protein
                     HisP"
                     /protein_id="HDX2526816.1"
                     /translation="MSENKLNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGK
                     STFLRCINFLEKPSEGSIVVNGQTINLVRDKDGQLKVADKNQLRLLRTRLTMVFQHFN
                     LWSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQR
                     VSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHV
                     STHVIFLHQGKIEEEGAPEQLFGNPQSPRLQQFLKGSLK"
     gene            complement(17136..17852)
                     /locus_tag="RN951_001809"
     CDS             complement(17136..17852)
                     /locus_tag="RN951_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX2526817.1"
                     /translation="MIEILHEYWKPLLWTDGYRFTGVAITLWLLILSVVIGGVLALFL
                     AIGRVSSNKYIQFPIWLFTYIFRGTPLYVQLLVFYSGMYTLEIVKGTEFLNAFFRSGL
                     NCTVLALTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGFSTFKMYRCIILPSALRIAL
                     PAYSNEVILMLHSTALAFTATVPDLLKIARDINAATYQPFTAFGIAAVLYLIISYVLI
                     SLFRRAEKRWLQHVKPSSTH"
     gene            complement(17849..18535)
                     /gene="hisQ"
                     /locus_tag="RN951_001810"
     CDS             complement(17849..18535)
                     /gene="hisQ"
                     /locus_tag="RN951_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012124147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter permease HisQ"
                     /protein_id="HDX2526818.1"
                     /translation="MLYGFSGVILQGALVTLELAISSVVLAVIIGLIGAGGKLSQNRL
                     SGLIFEGYTTLIRGVPDLVLMLLIFYGLQIALNTVTEAMGVGQIDIDPMVAGIITLGF
                     IYGAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPAMMRYALPGIGNNWQV
                     ILKSTALVSLLGLEDVVKATQLAGKSTWEPFYFAIVCGVIYLVFTTVSNGVLLFLERR
                     YSVGVKRADL"
     gene            complement(18625..19407)
                     /gene="hisJ"
                     /locus_tag="RN951_001811"
     CDS             complement(18625..19407)
                     /gene="hisJ"
                     /locus_tag="RN951_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter substrate-binding
                     protein HisJ"
                     /protein_id="HDX2526819.1"
                     /translation="MKKLVLSLSLVLAFSSATAAFAAIPQNIRIGTDPTYAPFESKNS
                     QGELVGFDIDLAKELCKRINTQCTFVENPLDALIPSLKAKKIDAIMSSLSITEKRQQE
                     IAFTDKLYAADSRLVVAKNSDIQPTVESLKGKRVGVLQGTTQETFGNEHWAPKGIEIV
                     SYQGQDNIYSDLTAGRIDAAFQDEVAASEGFLKQPVGKDYKFGGPSVKDEKLFGVGTG
                     MGLRKEDNELREALNKAFAEMRADGTYEKLAKKYFDFDVYGG"
     gene            complement(19628..20410)
                     /gene="argT"
                     /locus_tag="RN951_001812"
     CDS             complement(19628..20410)
                     /gene="argT"
                     /locus_tag="RN951_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine/arginine/ornithine ABC transporter
                     substrate-binding protein ArgT"
                     /protein_id="HDX2526820.1"
                     /translation="MKKSILALSLLVGLSTAASSYAALPETVRIGTDTTYAPFSSKDA
                     KGDFVGFDIDLGNEMCKRMQVKCTWVASDFDALIPSLKAKKIDAIISSLSITDKRQQE
                     IAFSDKLYAADSRLIAAKGSPIQPTLDSLKGKHVGVLQGSTQEAYANETWRSKGVDVV
                     AYANQDLVYSDLAAGRLDAALQDEVAASEGFLKQPAGKDFAFAGSSVKDKKYFGDGTG
                     VGLRKDDAELTAAFNKALGELRQDGTYDKMAKKYFDFNVYGD"
     gene            complement(20676..21245)
                     /gene="ubiX"
                     /locus_tag="RN951_001813"
     CDS             complement(20676..21245)
                     /gene="ubiX"
                     /locus_tag="RN951_001813"
                     /EC_number="2.5.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin prenyltransferase UbiX"
                     /protein_id="HDX2526821.1"
                     /translation="MKRLIVGISGASGAIYGVRLLQVLRDVTDIETHLVMSQAARQTL
                     SLETDFSLREVQALADVTHDARDISASISSGSFQTLGMVILPCSIKTLSGIVHSYTDG
                     LLTRAADVVLKERRPLVLCVRETPLHLGHLRLMTQAAEIGAVIMPPVPAFYHRPQSLD
                     DVINQTVNRVLDQFAITLPEDLFARWQGA"
     gene            complement(21340..22857)
                     /gene="purF"
                     /locus_tag="RN951_001814"
     CDS             complement(21340..22857)
                     /gene="purF"
                     /locus_tag="RN951_001814"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HDX2526822.1"
                     /translation="MCGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFR
                     LRKANGLVSDVFEARHMQRLQGNMGIGHVRYPTAGSSSASEAQPFYVNSPYGITLAHN
                     GNLTNAHELRKKLFEEKRRHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAAT
                     NRLIRGAYACVAMIIGHGMVAFRDPNGIRPLVLGKRDIDENRTEYMVASESVALDTLG
                     FDFLRDVAPGEAIYITEEGQLFTRQCADNPVSNPCLFEYVYFARPDSFIDKISVYSAR
                     VNMGTKLGEKIAREWEDLDIDVVIPIPETSCDIALEIARILGKPYRQGFVKNRYVGRT
                     FIMPGQQLRRKSVRRKLNANRAEFRDKNVLLVDDSIVRGTTSEQIIEMAREAGAKKVY
                     LASAAPEIRFPNVYGIDMPSATELIAHGREVDEIRQIIGADGLIFQDLNDLIDAVRAE
                     NPDIQQFECSVFNGVYVTKDVDQGYLDFLDTLRNDDAKAVQRQNEVENLEMHNEG"
     gene            complement(22894..23382)
                     /gene="cvpA"
                     /locus_tag="RN951_001815"
     CDS             complement(22894..23382)
                     /gene="cvpA"
                     /locus_tag="RN951_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin V production protein"
                     /protein_id="HDX2526823.1"
                     /translation="MVWIDYAIIAVIAFSSLVSLIRGFVREALSLVTWGCAFFVASHY
                     YTYLSVWFTGFEDELVRNGIAIAVLFIATLIVGAIVNFVIGQLVEKTGLSGTDRVLGV
                     CFGALRGVLIVAAILFFLDSFTGVSKSEDWSKSQLIPQFSFIIRWFFDYLQSSSSFLP
                     RA"
     gene            complement(23641..24303)
                     /gene="dedD"
                     /locus_tag="RN951_001816"
     CDS             complement(23641..24303)
                     /gene="dedD"
                     /locus_tag="RN951_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416817.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DedD"
                     /protein_id="HDX2526824.1"
                     /translation="MASKFQNRLVGTIVLVALGVIVLPGLLDGQKKHYQDEFAAIPLV
                     PKAGDRDEPDMMPAATQALPTQPPEGAAEEVRAGDAAAPSLDPTTIAANNTEFEPEPA
                     PVAPPKPKPVEPPKPKVEAPPAPKPEPKPVVEEKAAPTGKAYVVQLGALKNADKVNEI
                     VGKLRGAGYRVYTSPSTPVQGKITRILVGPDASKDKLKGSLGELKQLSGLSGVVMGYT
                     PN"
     gene            complement(24293..25561)
                     /gene="folC"
                     /locus_tag="RN951_001817"
     CDS             complement(24293..25561)
                     /gene="folC"
                     /locus_tag="RN951_001817"
                     /EC_number="6.3.2.12"
                     /EC_number="6.3.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tetrahydrofolate
                     synthase/dihydrofolate synthase"
                     /protein_id="HDX2526825.1"
                     /translation="MIIKRTPQAASPLASWLSYLENLHSKTIDLGLERVSQVAARLGV
                     LKPAPFVFTVAGTNGKGTTCRTLESILMAAGYKVGVYSSPHLVRYTERVRVQGQELPE
                     SAHTASFAEIESARGDISLTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVD
                     ADVAVVTSIALDHTDWLGPDRESIGREKAGIFRSEKPAIVGEPEMPSTIADVAQEKGA
                     LLQRRGVEWNYSVTDHDWAFSDAHGTLENLPLPLVPQPNAATALAALRASGLEVSENA
                     IRDGIASAILPGRFQIVSESPRVIFDVAHNPHAAEYLTGRMKALPKNGRVLAVIGMLH
                     DKDIAGTLAWLKSVVDDWYCAPLEGPRGATAEQLLEHLGNGKSFDSVAQAWDAAMADA
                     KAEDTVLVCGSFHTVAHVMEVIDARRSGGK"
     gene            complement(25631..26545)
                     /gene="accD"
                     /locus_tag="RN951_001818"
     CDS             complement(25631..26545)
                     /gene="accD"
                     /locus_tag="RN951_001818"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HDX2526826.1"
                     /translation="MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLE
                     VCPKCDHHMRMTARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKET
                     GEKDALVVMKGTLYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFS
                     ASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNI
                     AEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAK
                     LMNLPAPNPEAPREGVVVPPVPDQEPEA"
     gene            complement(26701..27360)
                     /locus_tag="RN951_001819"
     CDS             complement(26701..27360)
                     /locus_tag="RN951_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDX2526827.1"
                     /translation="MDLIYFLIDFILHIDVHLAELVAEYGVWVYAILFLILFCETGLV
                     VTPFLPGDSLLFVAGALASLETNDLNVHMMVVLMLIAAIVGDAVNYTIGRLFGDKLFS
                     NPDSKIFRRSYLDKTHQFYERHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYN
                     VIGALLWVLIFTYAGYFFGTLPFIQSNLKLMIVGIIFVSILPGVFEFIRHKRAAARAA
                     K"
     gene            complement(27443..28255)
                     /gene="truA"
                     /locus_tag="RN951_001820"
     CDS             complement(27443..28255)
                     /gene="truA"
                     /locus_tag="RN951_001820"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDX2526828.1"
                     /translation="MSDQQQPPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALS
                     QVANEPITVFCAGRTDAGVHGTGQVVHFETTAQRKDAAWTLGVNANLPGDIAVRWVKA
                     VPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGEND
                     FTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHN
                     QPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD"
     gene            complement(28255..29268)
                     /locus_tag="RN951_001821"
     CDS             complement(28255..29268)
                     /locus_tag="RN951_001821"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDX2526829.1"
                     /translation="MSEGWNIAVLGATGAVGEALLETLAERQFPVGEIYALARNESAG
                     EQLRFGGKTITVQDAAEFDWTQAQLAFFVAGKEATAAWVEEATNSGCLVIDSSGLFAL
                     EPDVPLVVPEVNPFVLTDYRNRNVIAVPDSLTSQLLAALKPLIDQGGLSRISVTSLIS
                     ASAQGKKAVDALAGQSAKLLNGIPIDEEDFFGRQLAFNMLPLLPDSEGSVREERRIVD
                     EVRKILQDEGLMISASVVQAPVFYGHAQMVNFEALRPLAAEEARDAFAQGEDIVLSEE
                     NEFPTQVGDASGTPHLSVGCVRNDYGMPEQVQFWSVADNVRFGGALMAVKIAEKLVQE
                     YLY"
     gene            complement(29334..30470)
                     /gene="pdxB"
                     /locus_tag="RN951_001822"
     CDS             complement(29334..30470)
                     /gene="pdxB"
                     /locus_tag="RN951_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-phosphoerythronate dehydrogenase PdxB"
                     /protein_id="HDX2526830.1"
                     /translation="MKILVDENMPYARDLFSRLGEVTAVPGRPIPVAQLADADALMVR
                     SVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSS
                     LLMLAERDGFSLHDRTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRADRGDEGDFRS
                     LDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALL
                     TCLNEGQKLSVVLDVWEGEPELNVELLTKVDIGTPHIAGYTLEGKARGTTQVFEAYSK
                     FIGHEQHVALDTLLPAPEFGRITLHGPLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPG
                     EFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR"
     gene            30569..31564
                     /gene="flk"
                     /locus_tag="RN951_001823"
     CDS             30569..31564
                     /gene="flk"
                     /locus_tag="RN951_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulator Flk"
                     /protein_id="HDX2526831.1"
                     /translation="MIQPISGPPPGQPPGQGDNLPSGAGNQPLSSQQRTSLESLMTKV
                     TSLTQQQRAELWAGIRHDIGLSGDSPLLSRHFPAAEHNLAQRLLAAQKSHSARQLLAQ
                     LGEYLRLGNNRQAVTDYIRHNFGQTPLNQLSPEQLKTILTLLQEGKMVIPQPQQREAT
                     DRPLLPAEHNALKQLVTKLAAATGEPSKQIWQSMLELSGVKDGELIPAKLFNHLVTWL
                     QARQTLSQQNTPTLESLQMTLKQPLDASELAALSAYIQQKYGLSAQSSLSSAQAEDIL
                     NQLYQRRVKGIDPRVMQPLLNPFPPMMDTLQNMATRPALWILLVAIILMLVWLVR"
     gene            complement(31561..32739)
                     /locus_tag="RN951_001824"
     CDS             complement(31561..32739)
                     /locus_tag="RN951_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2526832.1"
                     /translation="MTAVSQTETRSSANFSLFRIAFAVFLTYMTVGLPLPVIPLFVHH
                     ELGYGNTMVGIAVGIQFLATVLTRGYAGRLADQYGAKRSALQGMLACGLAGGALLLAA
                     ILPVSAPFKFALLVVGRLILGFGESQLLTGALTWGLGIVGPKHSGKVMSWNGMAIYGA
                     LAVGAPLGLLIHSHYGFAALAITTMVLPVLAWACNGTVRKVPALAGERPSLWSVVGLI
                     WKPGLGLALQGVGFAVIGTFVSLYFASKGWAMAGFTLTAFGGAFVVMRVMFGWMPDRF
                     GGVKVAIVSLLVETVGLLLLWQAPGAWVALAGAALTGAGCSLIFPALGVEVVKRVPSQ
                     VRGTALGGYAAFQDIALGVSGPLAGMLATTFGYSSVFLAGAISAVLGIIVTILSFRRG
                     "
     gene            complement(33004..34224)
                     /gene="fabB"
                     /locus_tag="RN951_001825"
     CDS             complement(33004..34224)
                     /gene="fabB"
                     /locus_tag="RN951_001825"
                     /EC_number="2.3.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase I"
                     /protein_id="HDX2526833.1"
                     /translation="MKRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGM
                     RSHVWGNVKLDTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRVGLI
                     AGSGGGSPRFQVFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSIS
                     SACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKA
                     SRTYDAHRDGFVIAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPSGEG
                     AVRCMKMAMHGVDTPIDYLNSHGTSTPVGDVKELAAIREVFGDKSPAISATKAMTGHS
                     LGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTDRELTTVMSNSFGF
                     GGTNATLVMRKLKD"
     gene            34383..36389
                     /gene="mnmC"
                     /locus_tag="RN951_001826"
     CDS             34383..36389
                     /gene="mnmC"
                     /locus_tag="RN951_001826"
                     /EC_number="1.5.-.-"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase
                     MnmD/FAD-dependent
                     5-carboxymethylaminomethyl-2-thiouridine(34)
                     oxidoreductase MnmC"
                     /protein_id="HDX2526834.1"
                     /translation="MKHYSIQPANLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLG
                     GNQLEVRFPEHPHPLFVVAESGFGTGLNFLTLWQAFDQFREAHPQAQLQRLHFISFEK
                     FPLTRADLALAHQHWPELAPWAEQLQAQWPMPLPGCHRLLLDEGRVTLDLWFGDINEL
                     TSQLDDSLNQKVDAWFLDGFAPAKNPDMWTQNLFNAMARLARPGGTLATFTSAGFVRR
                     GLQDAGFTMQKRKGFGRKREMLCGVMEQTLPLPCSAPWFNRTGSSKREAAIIGGGIAS
                     ALLSLALLRRGWQVTLYCADEAPALGASGNRQGALYPLLSKHDEALNRFFSNAFTFAR
                     RFYDQLPVKFDHDWCGVTQLGWNEKSQHKIAQMLSMDLPAELAVAVEANAVEQITGVA
                     TNCSGITYPQGGWLCPAELTRNVLELAQQQGLQIYYQYQLQNLSRKDDCWLLNFAGDQ
                     QATHSVVVLANGHQISRFSHTSTLPVYSVAGQVSHIPTTPELAELKQVLCYDGYLTPQ
                     NPANQHHCIGASYHRGSEDTAYSEDDQQQNRQRLIDCFPQAQWAKEVDVSDKEARCGV
                     RCATRDHLPMVGNVPDYEATLVEYASLAEQKDEAVSAPVFDDLFMFAALGSRGLCSAP
                     LCAEILAAQMSDEPIPMDASTLAALNPNRLWVRKLLKGKAVKAR"
     gene            complement(36510..36788)
                     /locus_tag="RN951_001827"
     CDS             complement(36510..36788)
                     /locus_tag="RN951_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcL family protein"
                     /protein_id="HDX2526835.1"
                     /translation="MIAEFESRILALIDGMVDHASDDELFASGYLRGHLTLAIAELES
                     GDDHSAQAVHTTVSQSLEKAIGAGELSPRDQALVTDMWENLFQQASQQ"
     gene            complement(36822..37370)
                     /gene="epmC"
                     /locus_tag="RN951_001828"
     CDS             complement(36822..37370)
                     /gene="epmC"
                     /locus_tag="RN951_001828"
                     /EC_number="1.14.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P hydroxylase"
                     /protein_id="HDX2526836.1"
                     /translation="MNSTHHYEQLIEIFNSCFADEFNTRLIKGDDEPIYLPADAEVPY
                     NRIVFAHGFYASAIHEISHWCIAGKARRELVDFGYWYCPDGRDAQTQSQFEDVEVKPQ
                     ALDWLFCVAAGYPFNVSCDNLEGDFEPDRVVFQRRVHAQVMDYLANGIPERPARFIKA
                     LQNYYHTPELTAEQFPWPEALN"
     gene            complement(37370..38179)
                     /locus_tag="RN951_001829"
     CDS             complement(37370..38179)
                     /locus_tag="RN951_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDX2526837.1"
                     /translation="METFNSLFMVSPLLLGVLFFVAMLAGFIDSIAGGGGLLTIPALM
                     AAGMSPANALATNKLQACGGSISATIYFIRRKVVSLSDQKLNIAMTFVGSMSGALLVQ
                     YVQADVLRQILPILVICIGLYFLLMPKLGEEDRQRRMYGLPFALIAGGCVGFYDGFFG
                     PAAGSFYALAFVTLCGFNLAKATAHAKLLNATSNIGGLLLFILGGKVIWATGFVMLVG
                     QFLGARMGSRLVLSKGQKLIRPMIVIVSAVMSAKLLYDSHGQEILHWLGMN"
     gene            complement(38179..39003)
                     /gene="mepA"
                     /locus_tag="RN951_001830"
     CDS             complement(38179..39003)
                     /gene="mepA"
                     /locus_tag="RN951_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-insensitive murein endopeptidase"
                     /protein_id="HDX2526838.1"
                     /translation="MNKTAIALLALLASSASLAATPWQKITQPVPGSAQSIGSFSNGC
                     IVGADTLPIQSEHYQVMRTDQRRYFGHPDLVMFIQRLSSQVSNLGMGTVLIGDMGMPA
                     GGRFNGGHASHQTGLDVDIFLQLPKTRWTSAQLLRPQALDLVSRDGKHVVSTLWKPEI
                     FSLIKLAAQDKDVTRIFVNPAIKQQLCLDAGTDRDWLRKVRPWFQHRAHMHVRLRCPA
                     DSLECEDQPLPPPGDGCGAELQSWFAPPKPGTTKPEKKTPSPLPPSCQALLDEHVI"
     gene            complement(39007..40092)
                     /gene="aroC"
                     /locus_tag="RN951_001831"
     CDS             complement(39007..40092)
                     /gene="aroC"
                     /locus_tag="RN951_001831"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HDX2526839.1"
                     /translation="MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHD
                     LDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDVF
                     RPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQM
                     GDIPLEIKDWSLVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGL
                     GEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGI
                     LGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRHDPCVGIRAVPIAEA
                     MLAIVLMDHLLRQRAQNADVKTDIPRW"
     gene            complement(40127..41059)
                     /gene="prmB"
                     /locus_tag="RN951_001832"
     CDS             complement(40127..41059)
                     /gene="prmB"
                     /locus_tag="RN951_001832"
                     /EC_number="2.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3 N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDX2526840.1"
                     /translation="MDKIFVDEAVNELQTIQDMLRWSVSRFSAANIWYGHGTDNPWDE
                     AVQLVLPSLYLPLDIPEDMRTARLTSSEKHRIVERVIRRVNERIPVAYLTNKAWFCGH
                     EFYVDERVLVPRSPIGELINNKFAGLISKQPQHILDMCTGSGCIAIACAYAFPEAEVD
                     AVDISPDALAVAEQNIEEHGLIHNVIPIRSDLFRDLPKVQYDLIVTNPPYVDAEDMSD
                     LPNEYRHEPELGLASGTDGLKLTRRILGNAADYLADDGVLICEVGNSMVHLMEQYPDV
                     PFTWLEFDNGGDGVFMLTKEQLLAAREYFAIYKD"
     gene            41225..41776
                     /gene="smrB"
                     /locus_tag="RN951_001833"
     CDS             41225..41776
                     /gene="smrB"
                     /locus_tag="RN951_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease SmrB"
                     /protein_id="HDX2526841.1"
                     /translation="MKKKTTLSEEDQALFRQLMAGTRKIKQDTIVHRPQRKKISEVPV
                     KRLIQEQADASHYFSDEFQPLLNTEGPVKYVRPDVSHFEAKKLRRGDYSPELFLDLHG
                     LTQLQAKQELGALIAACRREHVFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPK
                     EYGGDAALLVLIEVEEWLPPELP"
     gene            complement(41849..42700)
                     /locus_tag="RN951_001834"
     CDS             complement(41849..42700)
                     /locus_tag="RN951_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001721620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2544 domain-containing protein"
                     /protein_id="HDX2526842.1"
                     /translation="MHKIRHVICLLVLALCASGIQAATKIATLYVPAGTTSVVAKYRF
                     HLSVLTPQSVEYGTYESNSTAAASLPLVSWTGSPPGPELRMERNNTTLPDSTCPGLEE
                     YDALSPVTAWSCNELVLGVYYDGDLHGCPWIVSSYVESASTMDQRFGAGIFIGPTKVS
                     SDCPTESLAPYDVSWNENYVVHNKVVRLQSTGGVIEQTLPTFLMENGKLCDGSNFDER
                     GAYCRFVAQQMTFSTSGCDNAKVTVTPEPQPITSRQLHDMKLRVDTTSRQPIDSTCRF
                     TYILNMY"
     gene            complement(42702..43241)
                     /locus_tag="RN951_001835"
     CDS             complement(42702..43241)
                     /locus_tag="RN951_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX2526843.1"
                     /translation="MKTAHIYSPGYALLAGLLLTASTGAQAVDNNLHFYGNLLSKSCT
                     LVVDGANLAEIHFPTVSNRDLMVSGQSAHLPVVFKLKDCKGPAGYNVKVTLSGTEDSG
                     QPGFLAVDDTSTAQGVGIGMETLDGKRVDINNTTGATFALTNGNNDINFRAWIQAKSG
                     RDVTIGDFTASLTATFEYI"
     gene            complement(43238..43726)
                     /locus_tag="RN951_001836"
     CDS             complement(43238..43726)
                     /locus_tag="RN951_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001709066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX2526844.1"
                     /translation="MKKFLLLLLCAGCGAVLAAEDDITFHGTLMSPPACSISGGQTIE
                     VQFRDLIIDSIDGNYGRQKVDYELSCDSDVRDPEWNMTLSWTGTATSYNDSAIETDVP
                     GFGIELQHDGQRFKLNEPLSINATDFSQKPKLEAVPVKAADAVLTDTTFSAYATLRVD
                     YQ"
     gene            complement(43723..44232)
                     /locus_tag="RN951_001837"
     CDS             complement(43723..44232)
                     /locus_tag="RN951_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001733155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX2526845.1"
                     /translation="MSHKFVAGAGLLVLAGWGISGLAVAGSDIKQVDLTLRILVDGPP
                     PCSVKGSAVKFGNVIINRIDGTNYQQDAKYTLNCGNKVSDDLRMQLKGNTAVINGETV
                     LSTDIAGLGVRIENAADNSLFAVGENNWTPFNVNTQPQLKAVPVKQSGVQLTPSEFNA
                     TMTMVVDYQ"
     gene            complement(44248..45000)
                     /locus_tag="RN951_001838"
     CDS             complement(44248..45000)
                     /locus_tag="RN951_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000482750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HDX2526846.1"
                     /translation="MFNLTNTAKIVVPALALLATAVSFSSHASVTPDRTRLVFNESDK
                     SISVTLRNNDPTLPYLAQSWIEDAKGNKISSPLAVLPPVQRIDAMMNGQVKVQGLPDI
                     NKLPADRESVFYFNVREIPPKSNKPNTLQIALQTRIKLFWRPKALENTSMKSPWQHKV
                     TLIRNGQDFTVNNPTPYYVIISNASAKKGGNPPAGFTPLMMEPKTSAPLNAKMDSVPV
                     LTYINDYGARMPLYFICTGNSCQVDEEQSRKG"
     gene            complement(45020..47662)
                     /gene="yfcU"
                     /locus_tag="RN951_001839"
     CDS             complement(45020..47662)
                     /gene="yfcU"
                     /locus_tag="RN951_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher protein YfcU"
                     /protein_id="HDX2526847.1"
                     /translation="MPDHSLFRLRILPWCIALAMSGSYSSVWAEDDIQFDSRFLELKG
                     DTKIDLKRFSSQGYVEPGKYNLQVQLNKQPLAEEYDIYWYAGEDDASKSYACLTPELV
                     AQFGLKEDVAKNLQWSHDAKCLKSGQLEGMEIKADLSQSALVISLPQAYLEYTYPDWD
                     PPSRWDDGISGIVADYSINAQTRHEENGGDDSNEISGNGTVGVNLGPWRMRADWQTNY
                     QHTRSNDDDEFSGDETQKKWEWSRYYAWRALPSLKAKLALGEDYLRSDIFDGFNYVGG
                     SVSTDDQMLPPNLRGYAPDISGVAHTTAKVTVSQMGRVIYETQVPAGPFRIQDLGDSV
                     SGTLHIRIEEQNGQVQEYDISTASMPYLTRPGQVRYKIMMGRPQEWGHHVEGEFFSGA
                     EASWGIANGWSLYGGALGDENYQSAALGVGRDLSTFGAVAFDVTHSHTKLDKDTAYGK
                     GSLDGNSFRVSYSKDFDQLNSRVTFAGYRFSEENFMTMSEYLDASDSGMVRTGNDKEM
                     YTATYNQNFRDAGVSVYLNYTRHTYWDREEQTNYNIMLSHYFNMGSIRNVSISMTGYR
                     YEYDNQADKGMYISLSMPWGDNSTVSYNGNYGSGTDSSQVGYFSRVDDATHYQLNVGT
                     SDKHTSVDGYYSHDGSLAQVDFSANYHEGQYTSAGLSLQGGATLTAHGGALHRTQNMG
                     GTRLLIDADGVADVPVEGNGAAVYTNMFGKAVVSDVNNYYRNQAYIDLNRLPENAEAT
                     QSVVQATLTEGAIGYRKFAVISGQKAMAVLRLSDGSHPPFGAEVKNDNEQTVGLVDDD
                     GNVYLAGVKPGEHMSVFWSGVAHCDINLPDPLPADLFNGLLLPCQHKGNVAPITSPAV
                     KPAIQEQTQRVTPTEPPTSISVNQ"
     gene            complement(47744..>48301)
                     /locus_tag="RN951_001840"
     CDS             complement(47744..>48301)
                     /locus_tag="RN951_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDX2526848.1"
                     /translation="KFVKTAIAAAMVMGVFTSTATIAAVNNGTARFYGTIEDSVCSIV
                     PDDHKLEVDMGDIGAEKLKNNGTTTPKSFQIRLQDCVFDTQETMTTTFTGTVSSANSG
                     NYYTIFNTDTGAAFNNVSLAIGDSLGTSYKSGMGIDQKIVKDTSTNKGKAKQTLNFKA
                     WLVGAADAPDLGNFEANTTFQITYL"
BASE COUNT        11766 a        13076 c        12120 g        11339 t
ORIGIN      
        1 gtaaagcata tacacctcat tattttgtca ttattaagtt attaacagca caatcgagcc
       61 ttcccctctg gcaaaatctt attctgcaga ccttcaaaac accgtcctgg gggagtacat
      121 tgttctaagc tgacttccac ggcagggagt ggcgataaca gcaaaaaagg tcaagattca
      181 tgtcccccat tgaaaaatcc agcaaattag agaatgtctg ttatgacatc cgtggtccgg
      241 tgctgaaaga agcaaaacgc ctggaagaag aaggtaacaa ggtactgaaa ctgaacatcg
      301 gcaacccagc cccgttcggt tttgacgcgc cagatgaaat cctcgttgac gtgatacgca
      361 acctgcctac cgctcaaggg tattgcgatt ccaaaggtct ttactccgcg cgtaaagcca
      421 tcatgcagca ctaccaggct cgtggcatgc gtgatgttac cgtggaagat atttacatcg
      481 gcaatggtgt atcggagctt atcgttcagg caatgcaggc attgctgaac agcggggacg
      541 aaatgttggt tcctgcacca gattacccac tatggaccgc ggcggtttcg ctttccagcg
      601 gtaaagcggt gcattatctt tgcgatgaat cctctgactg gttcccagac ctcgatgata
      661 ttcgcgctaa aattacgcct cgtacgcgtg ggatcgttat tatcaaccca aataacccaa
      721 ccggcgcggt atattccaaa gagcttttaa tggagattgt ggagattgca cgtcagcata
      781 atctcattat cttcgccgat gaaatttatg acaaaattct ttacgacgac gctgagcatc
      841 actcaattgc gccgctggca cctgacctgc tgaccattac ctttaacgga ctgtcgaaaa
      901 cgtaccgcgt tgcaggcttc cgtcaggggt ggatggtgtt gaacgggccg aaaaaacacg
      961 ccaaaggcta catcgaaggt ctggaaatgc tggcttcaat gcgcctgtgt gctaacgttc
     1021 ctgcgcaaca cgccattcag accgcgctgg gtggttatca gagcatcagt gaatttatta
     1081 cccctggcgg tcgtctttat gagcagcgta accgcgcgtg ggaactgatc aacgatattc
     1141 cgggcgtttc ctgcgtgaaa cctcgtggtg cgctgtatat gttcccgaaa atcgacgcca
     1201 aacgctttaa cattcacgac gatcagaaaa tggtgctgga tttcctgttg caggaaaaag
     1261 ttctgttggt gcaagggacg gcattcaact ggccgtggcc ggatcacttc cgcattgtca
     1321 cgctaccgcg tgtcgatgat atcgagctgt ctttgagcaa gttcgcgcgt ttcctttctg
     1381 gttatcatca gctgtaatct taatttcact gccggagatt gcatccggca gcgttatccc
     1441 gccacaatga cctgatgatg tcatcatacg taaggtcact atgaaacaga gccatttttt
     1501 tgcccatctc tcccgcctga aactcattaa ccgctggccg ctaatgcgca acgtgctgac
     1561 ggaaaatgtg tccgaacaca gtttgcaggt agcgatggtc gcccatgcgc tggcagctat
     1621 caaaaatcga aaatttggcg gtaatgtcaa cgccgaacgt atcgctttac tggcgatgta
     1681 ccacgatgcc tcagaagtgc tcaccggcga tctccctact ccggtgaaat acttcaattc
     1741 gcaaatcgct caggagtaca aggctattga aaaaatcgct cagcaaaaac tggtcgatat
     1801 ggttccggaa gagctgcggg atatctttgc gccgttaatt gacgagcatg catatagcga
     1861 tgaagaaaaa tcgctggtga aacaggcaga tgcactgtgt gcatatctga aatgtctgga
     1921 agaactcgcg gccggaaata atgaattctt gctggcaaaa acgcgactgg aagcgacgct
     1981 tgaatcgcgt cgcagccagg agatggacta cttcatggaa gtatttgttc ccagcttcca
     2041 tctttcgctc gatgagatta gccaggattc accgctgtaa gcagccggag tctgcgtcgc
     2101 atcaggcaat aagcgccgga tgcgacatca ggctcttgtc aaaacggaaa cagcatcggg
     2161 atcatcacca cacaaaccgc catcacaata atggtgaacg gtacccccaa cttcacaaag
     2221 tcactgaagc tgtaatttcc cggacctaaa accagtgtgt taacaggtga agaaaccggt
     2281 gtcataaagg cggcggatgc tgccatcgcc acgaccatcg cgaatggata aggcgacacc
     2341 cccatcgttt tggcagcagc cagcgcaatc ggagccatca acaccgccgt cgcggtatta
     2401 gagataaata gcccaataac cgccgacaag acaaacaaac aacccagcat catatgtggc
     2461 ccgtaaccac cgccaatgtc catcagccct ttcaccgcca gcgcgacacc tcccgttttc
     2521 tgtaatgcca cagcaaacgg catcatccca acgatcaaaa taatgctcgg ccagtgaatg
     2581 gatttatagg cgctttcagc atctatacag cggaatttcc ccatcagcag gcaggcgatg
     2641 atagcggcaa caggattagg aatttcatct gtcagcatta acgccaccat tagcaccaga
     2701 cagaaaatgg catggggtgc ctggctgtgc gcgggcgatg cttcactcac ctcttccggt
     2761 aagttcagcg ctacgaagtc gcggccctgt ttggccagca taccgatcag tttccagtta
     2821 cccacaacca ggatgatatc gcccagcagc agaggctcat ccgccagcga accttccagc
     2881 gccacgccat tgcgctttag ccccaccaca ttcagtccgt agcgggtacg aaaaccaatt
     2941 tcgcgcaccg atttaccaat cagttctgac tcaggaatta atgaaatctc tgccatgccc
     3001 acatcaaggg cctggtcaga aaaatactcg ccgcgcagta ccatcggctc cagcaattgc
     3061 tcactacaaa attgccggag atcgacatca gccgcagaca tatcaataag caaaacgtca
     3121 cgcgcgcgaa attcagaaac cccattaacg ttcacgataa cgcgacgaaa acgccgccag
     3181 cgttcaacac cgatgacgtt agcgccataa cgctcacgta atttgagatc atccagccgt
     3241 tgaccaatca ttggcgatcc ggggcgaata gccagacgtc gcgcacgccc ggtcagtcga
     3301 tattcacgga taagatcgcg aaaggttcga cgcgtccagc cttcgcgctg cggggtctgg
     3361 gtatcccctt tcagcatgaa acgcatcact aacatataca aaatacccag caccagcacg
     3421 accaggccaa taggtgttac gctaaagaaa ctgaagccgt gatagccttc acgcagcaat
     3481 tcactgttga ctaccaggtt cggcggcgtc gccaccagcg tcatcatgcc gcttatcagc
     3541 ccggcaaaac tcaacggcat catcagacgt gacggcgaag tttgcatacg catggcaacg
     3601 cttaacacca cgggaataaa gatagcgaca acgccggttg aactcataaa cgcgccaagc
     3661 cccgcgacgg tcagcatcaa caaaaccaac attttgattt cactgttgcc cgcaactttg
     3721 accagccatg ttcccattac ggtggcaaca ccggtacgga ccaaaccatc gccaataata
     3781 aacaaggcgg caatcaggac aacgttagga tcagaaaagc cggaaaatac ttcggggact
     3841 gtcagcgttc cgcttaatgc aaacgcgaca ataacaaaca aagcgaccgc atccatacgc
     3901 actctgcccg tcgcaaacaa gacaatggca acggccagta atgaaagaac ccaaatcaat
     3961 tcaccgttca caacttatcc ttgttaattg agggagatgt cttgattctg ccataaaaaa
     4021 gccccgacga gacggggcta aatcatgatc aggtgtttca ctgaataata acatcgccat
     4081 ttggctgttt ggtcacagta atttgctcca gactgtggag gaccaaatcg acctcattca
     4141 ggcgcggggt atctgccgga gcgttaaccg caatgacatg gcaacccgcc gccaggccag
     4201 aaagcacgcc agcgggagca tcttccacca ccacacactc ctgcggcgca agccccagca
     4261 gctgcgcacc taacagatac gcatcaggtt ctggttttcc gcgcttcact cgctcagcgg
     4321 ttacaaacac ctctggtgcg ggaagcccag ctattttatg gcgcgctcgc gctaccggca
     4381 tggagccaga agtcacaatg gcccacggaa tacctgcttt attcaaatga ttgagtaagg
     4441 cgattgcccc cggaagcgcg gtaatacctt cggtttccgt ggcctcgatg tgctccagac
     4501 gcgtaaactc ggcggcaata tcagcctcgg atttgcccgc cataaaatgg cgcaaagagg
     4561 tgatcgcctg tttaccgtga atgaaagcca gcacctcttc cggcgctaac ccatgacgtc
     4621 tggcccagtt gctccacgcc cgttctaccg caggcaggga atccaccagc gttccatcaa
     4681 gatcaaacag aaaacctttg caccgcacgc gggcctcctc aggcgttgat aatttgatta
     4741 atttcgttgg cgctcaaatg gtactgacgc gggcaggcat gccacacatt aagcatgcgc
     4801 tgatattttt cccacattgg cgtctgggcg ttaaaaccgt gagttccggc gtcaaaatgg
     4861 gtatagcgcc cttccacatt aaccataaag cggacataac cgaggtaacg tgcttcagtg
     4921 gcggcgtcaa agccgaggaa ggtgacacga cgttcatcga tggattgctg gtcctgcaaa
     4981 ttagaccagg aaacatgcaa cgcatgatac atctccataa tgtcgatgat agtgcggcag
     5041 gtttcttctt tcagctcgcc aaactcgcga tccaattcac gcatctgtaa tccgtaacca
     5101 cgctcaataa ttgtttgcag gcgacggtaa cgttcagcat ttgccggatc gagcatagtc
     5161 atcatcttgt actgattaga caaaataaga cgttgcgcgt tggtcatttc cattgttgac
     5221 tcctgtatca ctctactacg gtgaaaaaaa agaaggctga gtatgccttc ttttatatgc
     5281 gtaatcaggg gtcaattaca aatcatcaag gaaagtttta tccagttgtt tgaaggcgcg
     5341 cttaagcgtg tcagctaatg cctggtaatc aggcttgcct tcaacgggtg ccaacacctg
     5401 tccagactcc tgcaatttac cgcgaacttc ataaaaccag ttgaggatag cagggggtaa
     5461 tggcgttaca gaacgcttgc ccagccacca taatccctgc atgggtaaac ttaaggcgaa
     5521 cagcgcagtg gcaactgccg gcccaagctg accgcccagg gcaatctgcc agcagagagt
     5581 aaatacggcg atcggcggca taaaacggat cgcataacgc gtcatcttga taacgcgatt
     5641 ttcgacaaag accggggcaa ggcgtttttc cagcggccac gtctttgagt aatgctgtcc
     5701 ccggcgaaac aagctaaaaa aattaacaga acgattatcc ggcgttgaca tgcttcacct
     5761 caacttcaca tataaagatt caaaaatttg tgcaaattca caactcagcg ggacaacgtt
     5821 caaaacattt tgtcttccat acccactatc aggtatcctt tagcagcctg aaggcctaag
     5881 tagtacatat tcattgagtc gtcaaattca tatacattat gccattggct gaaaattacg
     5941 caaaatggca tagactcaag atatttcttc catcatgcaa aaaaaatttg cagtgcatga
     6001 tgttaatcat aaatgtcggt gtcatcatgc gctacgctct atggctccct gacgtttttt
     6061 tagccacgta tcaattatag gtacttccat gtcgagtaag ttagtactgg ttctgaactg
     6121 cggtagttct tcactgaaat ttgccatcat cgatgcagta aatggtgaag agtacctttc
     6181 tggtttagcc gaatgtttcc acctgcccga agcacgtatc aaatggaaaa tggacggcaa
     6241 taaacaggaa gcggctttag gtgcaggcgc cgctcacagc gaagcgctca actttatcgt
     6301 taatactatt ctggcacaaa aaccagaact gtctgcgcag ctgactgcta tcggtcaccg
     6361 tatcgtacac ggcggcgaaa agtataccag ctccgtagtg atcgatgagt ctgttattca
     6421 gggtatcaaa gatgcagctt cttttgcacc gctgcacaac ccggctcacc tgatcggtat
     6481 cgaagaagct ctgaaatctt tcccacagct gaaagacaaa aacgttgctg tatttgacac
     6541 cgcgttccac cagactatgc cggaagagtc ttacctctac gccctgccgt acaacctgta
     6601 caaagagcac ggcatccgtc gttacggcgc gcacggcacc agccacttct atgtaaccca
     6661 ggaagcggca aaaatgctga acaaaccggt agaagaactg aacatcatca cctgccacct
     6721 gggcaacggt ggttccgttt ctgctatccg caacggtaaa tgcgttgaca cctctatggg
     6781 cctgaccccg ctggaaggtc tggtcatggg tacccgttct ggtgatatcg atccggcgat
     6841 catcttccac ctgcacgaca ccctgggcat gagcgttgac gcaatcaaca aactgctgac
     6901 caaagagtct ggcctgctgg gtctgaccga agtgaccagc gactgccgct atgttgaaga
     6961 caactacgcg acgaaagaag acgcgaagcg cgcaatggac gtttactgcc accgcctggc
     7021 gaaatacatc ggtgcctaca ctgcgctgat ggatggtcgt ctggacgctg ttgtattcac
     7081 tggtggtatc ggtgaaaatg ccgcgatggt tcgtgaactg tctctgggca aactgggcgt
     7141 gctgggcttt gaagttgatc atgaacgcaa cctggctgca cgtttcggca aatctggttt
     7201 catcaacaaa gaaggtaccc gtcctgcggt ggttatccca accaacgaag aactggttat
     7261 cgcgcaagac gcgagccgcc tgactgcctg atttcacacc gccagctcag ctggcggtgc
     7321 tgttttgtaa cccgccaaat cggcggtaac gaaagaggat aaaccgtgtc ccgtattatt
     7381 atgctgatcc ctaccggaac cagcgtcggt ctgaccagcg tcagccttgg cgtgatccgt
     7441 gcaatggaac gcaaaggcgt tcgtctgagc gttttcaaac ctatcgctca gccgcgtacc
     7501 ggtggcgatg cgcccgatca gactacgact atcgtgcgtg cgaactcttc caccacgacg
     7561 gccgctgaac cgctgaaaat gagctacgtt gaaggtctgc tttccagcaa tcagaaagat
     7621 gtgctgatgg aagagatcgt cgcaaactac cacgctaaca ccaaagacgc tgaagtcgtt
     7681 ctggttgaag gtctggtccc gacacgtaag caccagtttg cccagtctct gaactacgaa
     7741 atcgctaaaa cgctgaatgc ggaaatcgtc ttcgttatgt ctcagggcac tgacaccccg
     7801 gaacagctga aagagcgtat cgaactgacc cgcaacagct tcggcggtgc caaaaacacc
     7861 aacatcaccg gcgttatcgt taacaaactg aacgcaccgg ttgatgaaca gggtcgtact
     7921 cgcccggatc tgtccgagat tttcgacgac tcttccaaag ctaaagtaaa caatgttgat
     7981 ccggcgaagc tgcaagaatc cagcccgctg ccggttctcg gcgctgtgcc gtggagcttt
     8041 gacctgatcg cgactcgtgc gatcgatatg gctcgccacc tgaatgcgac catcatcaac
     8101 gaaggcgaca tcaatactcg ccgcgttaaa tccgtcactt tctgcgcacg cagcattccg
     8161 cacatgctgg agcacttccg tgccggttct ctgctggtga cttccgcaga ccgtcctgac
     8221 gtgctggtgg ccgcttgcct ggcagccatg aacggtgtag aaatcggtgc cctgctgctg
     8281 actggcggct acgaaatgga cgcgcgcatt tctaaactgt gcgaacgtgc tttcgctacc
     8341 ggcctgccgg tatttatggt gaacaccaac acctggcaga cctctctgag cctgcagagc
     8401 ttcaacctgg aagttccggt tgacgatcac gaacgtatcg agaaagttca ggaatacgtt
     8461 gctaactaca tcaacgctga ctggatcgaa tctctgactg ccacttctga gcgcagccgt
     8521 cgtctgtctc cgcctgcgtt ccgttatcag ctgactgaac ttgcgcgcaa agcgggcaaa
     8581 cgtatcgtac tgccggaagg tgacgaaccg cgtaccgtta aagcagccgc tatctgtgct
     8641 gaacgtggta tcgcaacttg cgtactgctg ggtaatccgg cagagatcaa ccgtgttgca
     8701 gcgtctcagg gtgtagaact gggtgcaggg attgaaatcg ttgatccaga agtggttcgc
     8761 gaaagctatg ttggtcgtct ggtcgaactg cgtaagaaca aaggcatgac cgaaaccgtt
     8821 gcccgcgaac agctggaaga caacgtggtg ctcggtacgc tgatgctgga acaggatgaa
     8881 gttgatggtc tggtttccgg tgctgttcac actaccgcaa acaccatccg tccgccgctg
     8941 cagctgatca aaactgcacc gggcagctcc ctggtatctt ccgtgttctt catgctgctg
     9001 ccggaacagg tttacgttta cggtgactgt gcgatcaacc cggatccgac cgctgaacag
     9061 ctggcagaaa tcgcgattca gtccgctgat tccgctgcgg ccttcggtat cgaaccgcgc
     9121 gttgctatgc tctcctactc caccggtact tctggtgcag gtagcgacgt agaaaaagtt
     9181 cgcgaagcaa ctcgtctggc gcaggaaaaa cgtcctgacc tgatgatcga cggtccgctg
     9241 cagtacgacg ctgcggtaat ggctgacgtt gcgaaatcca aagcgccgaa ctctccggtt
     9301 gcaggtcgcg ctaccgtgtt catcttcccg gatctgaaca ccggtaacac cacctacaaa
     9361 gcggtacagc gttctgccga cctgatctcc atcgggccga tgctgcaggg tatgcgcaag
     9421 ccggttaacg acctgtcccg tggcgcactg gttgacgata tcgtctacac catcgcgctg
     9481 actgcgattc agtctgcaca gcagcagtaa tctcgtcatc atccgcagct ttgcgctgcg
     9541 gatatctgaa ccggaaataa tcactatttc cggtttttta ttctcttaat ctgcattaat
     9601 cctttctgat tatcttgctt aactgcgctg catcaatgaa ttgcgccatt tcactttgca
     9661 tacttaccac tttgttttgt gcaagggaat atttgcgcta tgtccgcaat cactgaatcc
     9721 aaaccaacaa gaagatgggc aatgcccgat acgttggtga ttatcttttt tgttgctatt
     9781 ttaaccagcc ttgccacctg ggtagttccg gtggggatgt ttgacagtca ggaagtgcag
     9841 tatcaggttg atggtcaaac aaaaacacgc aaagtcgtag atccacactc atttcgcatt
     9901 ctgactaacg aagcaggcga acctgagtat caccgcgtac agctgttcac gacgggcgat
     9961 gaacgcccgg gcctgatgaa cttcccgttt gaaggattaa cctcaggatc gaaatacggg
    10021 acagccgttg gcatcatcat gtttatgctg gtgattggcg gcgcgtttgg cattgtgatg
    10081 cgtacaggaa ccattgataa cggtatcctg gcgcttattc gccatacccg cgggaatgaa
    10141 attctcttta ttcctgcgct gtttattctg ttttcacttg gcggcgcggt atttggtatg
    10201 ggagaagagg ccgtcgcctt tgccattatc atcgcaccgc taatggtccg gctgggctat
    10261 gacagtatta ccaccgtcct ggtgacctat attgccacgc aaatcggttt tgccagttcg
    10321 tggatgaacc cgttttgtgt ggtcgttgct caggggattg ccggcgttcc ggtgctttct
    10381 ggctccgggt tgcgcatcgt ggtgtgggtt atcgccactc tgattggcct gatctttacc
    10441 atggtgtacg cctcacgagt gaaaaagaat cctcttctgt cacgcgtgca tgagtccgac
    10501 cgcttctttc gtgaaaagca ggctgatgtt gaacaacgtc cgtttacctt tggtgactgg
    10561 ctggtattga ttgtcctgac cgccgtaatg gtctgggtga tttggggcgt gatcgttaat
    10621 gcctggttta ttccagaaat tgccagccag ttcttcacca tgggtctggt gattggcatc
    10681 atcggcgttg ttttccgcct taacggcatg acggttaata ccatggcttc atcctttacc
    10741 gaaggggcgc gaatgatgat cgcccctgcc ctgctggtgg gtttcgccaa agggattttg
    10801 ctgctggtcg gtaatggtga agcgggtgat gccagcgtgt taaataccat cctcaacagc
    10861 attgccaatg ccattagcgg tctggacaac gcggtcgcgg cctggtttat gttgctcttc
    10921 caggcggtat ttaatttctt cgtgacgtcc ggttctggtc aggcggcgtt aaccatgccg
    10981 ttactggcac cgcttggcga tctggtcggt gttaaccgtc aggttaccgt gctggcgttc
    11041 cagtttggtg atggcttcag tcacatcatt tacccaacct cagcgtcgtt aatggcaacg
    11101 ctcggtgtgt gcagggtgga cttccgtaac tggctgaagg tgggcgcgac cctacttgga
    11161 ctgctgttta ttatgtccag cgtcgtagtg atcggcgctc agttgatggg ctaccactaa
    11221 aaatgttaag agccgcaatt gcggctcttt tttcattctg ccgtttcagt ctctacggct
    11281 tcatttttgg cattgcgctt catccacaac gctagcgctt tcagcgagtc tggagtgaac
    11341 tcatcgcagc gtgcggtgat ttcttccggc gtcagccagc aaacttcact gacttcatct
    11401 tcctgtagtg cgaagggacc gtgagagacg cagctgaaca atgcgcccca gacacggcaa
    11461 tttttatctt cgaaatagaa ctgcccgtgc tcggcaaagg ggacaccggc aatgcccaac
    11521 tcttcttccg cttcgcgacg cgcggattcc agcagttgct catcggcctg aaccacaccg
    11581 cctgcggtcg catctaacat gccgggtaaa aagtcttttg tctcggtacg acgctggacc
    11641 agaattttgc ccatgccatc atgcacgacg atgtaagttg cacgatgacg cagacactgt
    11701 gcccgcattt gttcccggct ggcttgtgca atgacttcgt tctcttcatt gacaatatcc
    11761 acccattcag tacttgccaa acgacgctgt tccattatca ggaaaccttc tttttctggc
    11821 gctcttacgg cgcattttga gttgtgggta aattacggat taatcgcgac ctgcgcaatg
    11881 atactttgat cattgagtgc gattacacta agtacgtcat tatccagcat gccataactc
    11941 gccggattac cgcctttcgg aatactcacc gagccggggt tgaaatggaa aatctccccc
    12001 cgctgttctg ccactggcag atgggtatga ccgtacacca gcacatcgtt ctggtttaaa
    12061 gcaggtagat tttccgggcc aaaaagatga ccatgcgtca aaaacagacg ttgtttttcc
    12121 agtaatacct gttgccacgg cgcggttatc gggaaatgca gcagcatttg atccacttcg
    12181 ctgtcgcagt tgccgcgcac agcgataacc ttatgtgcca cttcattaag ccgttcagcg
    12241 actttggctg gcgcgtaacc ctccggtaaa gcattacgcg ggccgtgatt caacacgtcg
    12301 ccaaggatca ccagccactg ggcaccgctt tgggcaaaca actccagaac acgttccgtc
    12361 gccggtaacg acccatgaat gtccgatgca aacatcagtt tcatcactca ctcctcgtcg
    12421 aaaaaacgta agctatgata ctggattctg tcgttgctat cagccagatt gcttcgccga
    12481 aagtgcaata aaacgctgga cagacgctcg ctgccactgg aatgtcgcat aatccaccag
    12541 gcgttctggc acctcatcgc catgtagtac caggcggtta atcattagcg ccagatcagt
    12601 atcagcaatg caccattcac caaataaatt cggctgaccc agtactaaca aatgttctgc
    12661 catcgcaaac agtttctctg cactggcttt tccctcggcc gttagtggcg cttttttcgc
    12721 ccccgcaaag acaacatccg tcggacgctc ttcgcggatg ggcatcagat cgctgcgcag
    12781 ccaggcctga atctgtcgtg cacgcgcacg attttctaaa tcaagcggat aaatacgttc
    12841 ccaggtcggt ggcgcaaatc gatcttccag atactccgca atggcagaag attcactcaa
    12901 ctcaaaatca tcgatttgta ataacggcac acggcgtgtc tgaccgtaac cttgccacgt
    12961 cggctgcaaa tgttcaccgc tgtcgaggtc gatggtcttg atatgaaacg acaggccttt
    13021 ttcctgcaac gccacccagg cggataacac ataaggggag aaaaagtggg catctgacca
    13081 aagcgtgata gcgggtttac tcattatgtc ctcggcaata aagggggctg gctatcaaac
    13141 tatagagcct ttttgtcact gtcacgtgac gaatactcac gtaattcgcc gcgctttcta
    13201 tacttgtggt gttcagatga ttaaacaacc ggagctgcaa tgatcgatct ctatttcgcc
    13261 ccgacaccca atggtcacaa aattacgctg tttctcgaag aagcagagct tgattatcgc
    13321 ttgattaagg tagacctggg gaaaggcggt cagtttcgtc cggaattttt gcgcatttcg
    13381 cccaacaaca aaattccggc aattgttgat cattctcctg ccgatggcgg cgaaccgtta
    13441 agcctctttg agtctggtgc cattttgttg tatctggctg agaaaacagg actctttttg
    13501 agtcatgaaa cgcgtgagcg cgccgccaca ttacagtggt tattctggca ggtaggcgga
    13561 ctggggccga tgcttgggca aaatcatcat tttaatcacg cagcccccca aaccattcct
    13621 tacgctattg aacgttatca ggttgaaact cagcgtcttt accatgtact gaacaagcgg
    13681 ctggaaaact cgccctggct gggaggcgag aactacagca ttgcggatat tgcctgctgg
    13741 ccgtgggtta atgcctggac tcgccagcga attgacctcg caatgtatcc ggcagtcaag
    13801 aactggcatg agcggatccg ttcgcgccct gccaccgggc aggcactgct aaaagcacaa
    13861 ctcggtgatg agcgttcgga tagttaacag aaacaggttc tcgtgtatta tttcatccta
    13921 agtaaaacaa cggagaacct gcaatggcac aacctgccgc tattattcgt ataaagaacc
    13981 ttcgtttacg tacgtttatc ggaattaagg aagaagaaat taacaaccgt caggatattg
    14041 ttatcaatgt gacgatccac taccccgccg ataaagcgcg cactagcgaa gatatcaacg
    14101 atgcgctgaa ttatcgcacc gtaacgaaaa acattattca gcatgtagag aataaccgtt
    14161 tctctttgtt ggaaaaatta actcaggatg tgctcgatat cgcacgtgaa catcactggg
    14221 tgacgtatgc tgaagtggag atcgataaac tgcacgcgct gcgctacgcc gattcggtat
    14281 ccatgacctt aagctggcag cgttaaccgc catatcggga ggctgcatga acatagtgat
    14341 caccggaggg acgggattaa ttggtcgcca tttgattccg cgtttgctgg agctgggcca
    14401 tcaaatcacg gtagtgacgc gtaacccaca gaaagccagt tccgttctcg gccctcgggt
    14461 gacgctatgg caagggctag ccgctcaaag caacctcaac ggcgttgatg cggtaatcaa
    14521 cctggccgga gaaccgattg ctgataaacg ctggactcac gagcaaaaag agcgtctctg
    14581 ccaaagccgc tggaatatca cgcaaaaact ggtcgatttg attaatgcca gcgacacgcc
    14641 gccgtcggta ctcatttccg gctcggcaac gggctattat ggcgacttag gtgaagtggt
    14701 ggttaccgaa gaggaaccgc cgcataacga atttacccat aaactctgcg cccgctggga
    14761 agaaattgcc tgccgggcgc aaagtgacaa aacgcgagtg tgcctgctgc gtaccggtgt
    14821 agtgctggca ccggatggcg gtattctcgg taaaatgctg ccgccgtttc gtcttggcct
    14881 gggcgggccg attggctctg gtcggcagta tctggcctgg attcatattg atgatatggt
    14941 caacggtatt ctctggctgc tggataacga gctgcgcggg ccatttaata tggtttcgcc
    15001 ctacccggta cgcaatgaac aatttgccca tgcgctcggt catgcgctgc atcgcccggc
    15061 cattttgcgc gtccccgcga ccgccattcg actgttaatg ggcgaatctt cagtactggt
    15121 attaggtgga caacgcgcgc tgcctaaacg gctggaagaa gcgggttttg cgtttcgctg
    15181 gtacgattta gaagaggcgc tggcggatgt cgttcgctga tgtggtttac agcaaacatc
    15241 cgccagttaa ctcccggtgt tacaggatta gtggctttgc gcgataagat cgtctggtga
    15301 aagtcgggtc accatcatga ctaactctct gtctaaacct ctatccagca tctcctgagc
    15361 aatacgcagg gcttcttcgt gtttgccctg cattgcgcct tcttcacgta atctgtcagc
    15421 aatggtcatc agtttctcct tttcttgtgg tgcgcgttcc gctatctcac caataaatgc
    15481 acgaaaacgc tgggcatccc ctgtttgtaa tacgtaatta aacagggctt ttagctgtct
    15541 gtcattagtg ttccctgtaa ctagcagcga aacaatttgg tcgactaatc ccaacagatc
    15601 gcgctgacga atatgtttct gaattaactc caacagcgcc attttgcggt gttgcataat
    15661 ctcgtcatcc ggcaccacgg taatatccac caacggaaac gctgatgaat atattttgcg
    15721 ggctatagca ggctcggcaa attcatcaag ccagcagagt gaataaggat aaggacttct
    15781 gcaaccatga taaaacagca tcgggatcac caatggaagc tctttatagc ccgcatcaag
    15841 atggttttgc attgccgcaa tggaataacg catcatgcga aaagccatta attcttccgg
    15901 cttactttgg tgctctatca ctacataaat ataacccact ccctcctgcg ttttcacaga
    15961 ccacaagagg tcggaataat attgccgcag gtcttcatca ataaaactgt ttggttctag
    16021 tttaagcgtc gttaaatcac acagtttgcg aagcggcgcg ggaagatgaa tatcaataaa
    16081 atcccgcgcg gtgtctggat ggcgtaaaaa agatttaaat accgcatcat gcggcgtgga
    16141 agttgtcgat attgtcatgg cgttccgtca cccctcaaat ttaagatgac gcgacaataa
    16201 ccacgattaa cacccaatgc agcaggcagt ttttatcttt ggacagcgaa ttcagaagta
    16261 tttttagcgg actgcaactt ttacatttca gcggaagctg actcacaaat tccccatgaa
    16321 aatactccgg cagcgttagc caccggagag gaaattattt cagcgatccc ttaaggaact
    16381 gttgcagacg agggctttgc gggttgccaa ataactgctc cggcgcgccc tcttcttcta
    16441 ttttcccctg atggaggaaa atgacgtgag tagaaacatg gcgagcaaag cccatttcgt
    16501 gagtcactac caccatggtt ttcccctctt ctgccagttg ctgcataata cgtaacactt
    16561 cgcctaccag ttcaggatcg agcgccgagg taggttcatc aaacagtaaa acttccggtt
    16621 ccatcgccag cgcccgcgcg atagaaacac gctgttgctg accgccggaa agatgcaccg
    16681 gatatttccc ctgcgcacgt tcgtctatcc cgacttttgc cagatacttg accgcccgct
    16741 cgcgcgcttc ctgcttgctc aggcccaaca cctgaatcgg cgcttccatg acgttttcca
    16801 gcaccgtcat atggctccag agattgaagt gctggaatac catcgtcagg cgtgtgcgca
    16861 gtaagcgcag ttgattttta tcggcgactt tgagttgacc gtctttgtcg cgcaccagat
    16921 tgatcgtctg gccattgacc acgatcgacc cttcactcgg tttttcgagg aagttaatgc
    16981 agcgcagaaa ggtacttttc cccgatcccg acgatccgat gatgcttatt acatctccgg
    17041 cattcgcttg cagtgagacc cctttcagca cttcatgttc gccgtagcgt ttgtgcaaat
    17101 cgataacgtt taatttattc tcggacatcg tattctcagt gcgttgaaga aggtttcaca
    17161 tgctgcaacc agcgtttttc cgctctgcga aagaggctga tcaggacata agagatgatt
    17221 aaatagagca ccgcggcaat gccgaaggcg gtaaaaggtt gatacgtggc ggcgttaata
    17281 tcgcgggcta ttttcagcag atccggcaca gtggccgtaa acgccagcgc agtagagtgc
    17341 agcatcagga tcacttcgtt gctgtatgcc ggtaacgcaa tacgcagcgc agaaggcaaa
    17401 ataatgcaac gatacatttt aaaagtcgag aagccatagg ctctggcggc ttcaatttcc
    17461 ccatgcggaa ccgaacggat tgccccagca aaaatctcgg tagtgtaagc gcaggtgtta
    17521 agcgtcagcg ccagcacggt acagttcagg ccactgcgga agaaagcgtt aaggaattcg
    17581 gttcccttaa caatctcaag cgtgtacatg ccggaataga acaccagcaa ctgaacatac
    17641 agcggcgtac cgcgaaaaat ataggtaaat aaccagattg gaaactggat gtatttatta
    17701 ctggagacac gaccaatcgc cagaaacagc gccaggactc cgcctatcac taccgacaaa
    17761 ataagcagcc acagagtgat cgccacacca gtaaagcgat aaccgtcggt ccacagcagc
    17821 ggtttccagt attcatgtaa gatttcgatc acaggtcagc cctcttcaca cccacggagt
    17881 agcggcgctc aaggaacagc agcacaccat tggaaacagt ggtgaaaacc aggtaaatca
    17941 cgccacagac gatggcgaaa tagaacggtt cccaggtact tttgcctgcc agttgggtgg
    18001 ctttgaccac atcttccagg ccgagtaacg aaaccagtgc ggtagatttg aggatcacct
    18061 gccagttgtt gccaatgcct ggcagggcgt aacgcatcat cgccggaaac atgatccgcc
    18121 gaaacacttg cccacgagta aaaccgaacg ccgtcgccgc ctctatatgt cctttcggca
    18181 ctgccataaa agcaccacgg aacgtttcgg taaaataagc accgtagata aaaccgagag
    18241 tgataatacc agcgaccatc ggatcgatat caatctgccc gacgcccatc gcctccgtca
    18301 ccgtgtttag cgcaatctgc aaaccgtaga aaatcagcag catcaacact aagtccggca
    18361 cgccacgaat cagcgtggtg tacccttcga aaatcagccc cgaaagccga ttttgcgaga
    18421 gcttaccgcc agcgccaatt aaaccgatga ttacagcgag cactacagag ctgatagcca
    18481 gctccagcgt gacgagcgca ccctgtaaaa taacacctga aaacccatac aacatgctgc
    18541 ctgtcctgtc gtgtgtggtg aattaccgcc tcttgtctcc ctccggttac ccgaagggag
    18601 cgggctttct ttcaccgatg gcgattaacc gccataaaca tcaaaatcga agtacttttt
    18661 cgctaatttc tcgtaagtac cgtcagcgcg catttcggca aaggctttgt tcagtgcctc
    18721 gcgcagttcg ttatcttctt tacgcaggcc catgccggtc cctacaccaa acagtttttc
    18781 atctttaaca gacgggccac cgaatttgta atctttaccg acaggttgtt tgaggaaacc
    18841 ttcgctggca gcgacctcat cctggaacgc ggcatcaata cgtccggcag tcaggtcaga
    18901 ataaatgttg tcctgcccct gatacgagac gatttcaatg ccttttggtg cccagtgttc
    18961 gttaccgaac gtctcctggg tggtgccctg caatacgcct acccgcttgc ctttcagcga
    19021 ctcgactgtc ggctgaatgt cggaattttt cgccaccacc agacgagaat cggcagcgta
    19081 cagtttgtcg gtgaaggcaa tttcttgctg acgtttttcc gtaatggaaa gcgatgacat
    19141 gatggcgtca atcttcttcg cttttaagga cgggattaac gcatccagcg gattttcgac
    19201 aaacgtacat tgcgtattga tgcgtttgca taattccttt gccagatcga tatcgaagcc
    19261 aaccagttcg ccttgtgaat tttttgattc aaatggcgca taggtcgggt cggtaccgat
    19321 gcggatgttt tgcggaatcg cagcaaatgc cgcagttgcg ctggagaagg ccagaaccag
    19381 agagagcgat agcaccagtt ttttcataat gtcctcaact gacagtcttt ttatagggaa
    19441 tatttacagg tttgttacac ttatcgtgcc ataaaattga ccatcaaggc aaaatatccc
    19501 gccccgttag acgtattatt tttcattaaa aatgcttaag tatgcatttc aatgcaccac
    19561 gatagtgcaa caaacctggc gtgcaccatg atgatcattc catcaggtac agcttcccag
    19621 cgacgtatca gtcaccgtag acattaaagt cgaaatactt tttcgccatc ttgtcgtagg
    19681 tgccgtcctg acgcagctcg ccaagcgcct tattgaaggc agccgtcagt tcagcatcat
    19741 ctttacgtag ccctacaccg gtgccatcac cgaagtattt tttgtctttt actgatgagc
    19801 cagcaaaggc gaaatcttta ccagcaggtt gcttgaggaa tccttcgctg gcagcaactt
    19861 catcttgtaa cgcagcatcc agacgtcctg cagccagatc ggaatagacc aaatcctggt
    19921 tggcataggc caccacatcc acgcctttgc tacgccaggt ctcgttagcg taagcttcct
    19981 gggttgatcc ctgcagcaca ccaacatgtt tacctttcag tgaatccagc gttggctgaa
    20041 tcggtgaacc tttggcagca atcaaacgag aatctgcggc gtacagcttg tcggagaagg
    20101 caatctcctg ctgacgttta tcggtaatgg aaagcgacga aataatggcg tcgatttttt
    20161 tcgctttcag tgaggggatc agcgcgtcaa agtcactggc aacccaggta catttcacct
    20221 gcatccgttt gcacatctcg ttaccgagat cgatatcaaa gccaacaaaa tcacctttag
    20281 catctttcga tgagaacggt gcgtaggtgg tatcggttcc gatacgtacc gtctccggta
    20341 gcgccgcata gctggaagcc gctgtggaga gaccgactaa caaagacaga gcgagaatcg
    20401 acttcttcat acataaccct caagtgaaaa tggctttttt atgttgtgta ttgtgttgtg
    20461 tgtttgcagg ctctttcatg caggtcttat gccatcttga cgacaacagt aacattcaac
    20521 gttaaatatg ttaataagac gttgcattat tgtcctgaag ttgaagatag caggtatagc
    20581 ggttgaatcg cagcgtttcg attgaatggc agaaacaaaa tgtcgaggat ttgatcgcgg
    20641 ttgcaaaatt gccctgaaac agggcaacag cggagttatg cgccctgcca gcgggcaaag
    20701 agatcttcag gaagggttat tgcaaactgg tcaagaacac gattaaccgt ctgatttatc
    20761 acatcatcaa gggattgcgg gcgatgataa aacgccggaa cgggaggcat aatcaccgca
    20821 ccgatttctg ccgcctgagt cattaaacgc agatggccta agtgcaatgg tgtttcacgc
    20881 acgcagagca ccaacgggcg acgctctttc agcaccacat ctgccgcacg ggtcagtaag
    20941 ccatcagtat agctatggac aatgccggaa agggttttga ttgaacaggg taaaatcacc
    21001 atccccagcg tctggaaaga accggaagag atgctggcgg aaatatcgcg cgcatcgtgc
    21061 gtgacatcag ctaatgcctg cacttcgcgc agggaaaaat ccgtttcgag ggataaggtc
    21121 tggcgcgccg cctggctcat caccagatgc gtttcgatat ctgtgacatc gcgcagaacc
    21181 tgtaataagc gcacgccata aatcgcgccg ctggcaccgc tgatgcctac aatgagtcgt
    21241 ttcataaata gttgccctgt cagacttgca ggcagacttt gcagtatttc ggcgggagtt
    21301 gcaagtcagg gtgccagacc ggcaccctca gcgaaggcat catccttcgt tatgcatttc
    21361 gagattttcc acttcgttct gacgttgcac tgctttggcg tcatcattac gtaacgtatc
    21421 gaggaaatcg aggtagccct gatcaacatc tttggtgacg tagacgccgt tgaacaccga
    21481 gcattcaaac tgctggatat ccggattttc agcgcgaacg gcgtcgatca gatcgttcag
    21541 atcctggaaa atcaacccgt cagcaccgat gatctggcga atttcatcaa cttcgcgacc
    21601 gtgagcgatc agttccgtgg cgctcggcat atcaatacca taaacgttcg ggaagcgaat
    21661 ttccggtgcc gcagaagcga ggtacacttt cttcgctccg gcttcgcgtg ccatctcgat
    21721 aatctgctca gaagtggtgc cacggacgat ggagtcgtcg accagcagga cgtttttatc
    21781 gcggaactcg gcgcggttgg cattcagttt acggcgcacg gacttacgac gcagctgctg
    21841 gcccggcatg ataaaggtgc ggccaacata gcggttttta acgaagccct ggcggtacgg
    21901 tttgcccaga atacgagcaa tttccagcgc gatatcacac gaggtttctg ggatcgggat
    21961 caccacgtcg atatccagat cttcccattc gcgggcaatt ttctcgccca gtttcgtgcc
    22021 catattcaca cgcgcgctgt aaacggaaat tttgtcgatg aacgagtccg ggcgagcaaa
    22081 gtatacatac tcaaacaggc acggattgct gaccggattg tcagcacatt gacgggtaaa
    22141 caactgccct tcttcagtga tgtaaatcgc ttcgcccggc gcgacgtcac gcaggaaatc
    22201 aaagcccagc gtatcgagcg ctacgctttc ggaagcgacc atatattctg tacggttctc
    22261 gtcaatatca cgttttccca gtaccagcgg acgaatcccg tttggatcgc ggaaagcaac
    22321 cataccgtgg ccgataatca tcgccacaca ggcatatgcg ccgcggatta agcggtttgt
    22381 ggcagcaatg gcagcgaaaa tattgtcggc ttccagcggg tagtggcgga agttgtccag
    22441 ctcgctagcg aagatattaa gcagaatttc cgagtcggaa gtggtgttga tgtggcggcg
    22501 tttttcttca aacaattttt tacgcaactc gtgagcgttg gtcagattgc cgttgtgggc
    22561 aagcgtaatg ccatacggag agttaacgta aaacggctgc gcttcagagg cgctggagct
    22621 gccagccgta gggtaacgca catgaccaat gcccatattg ccctgcaaac gctgcatatg
    22681 gcgagcttca aatacatcgc tcaccagccc gttcgcttta cgcaaacgga agcagttatt
    22741 ggcatctatg gtgatgatgc cggcggcatc ctgaccgcga tgctgaagca ccgttaaggc
    22801 atcataaatc gactggttaa ccggcataac accggcgata ccgacaatac cgcacatacg
    22861 tctttttcct cgttaagcca catctcagag cacttacgct ctgggcaaga aacttgacga
    22921 gctttgcaga taatcaaaaa accatctgat gataaaactg aactgcggga tcagctgtga
    22981 tttgctccag tcttcgcttt tcgacacccc ggtaaaggag tcgagaaaga agagaatggc
    23041 ggcaacaatc aacacaccgc gcaacgcacc gaaacagacg cccagcaccc gatcggtgcc
    23101 tgacaacccc gttttctcca ccaactggcc tatcacgaag ttcacgatag caccaacgat
    23161 cagggtagcg ataaacagta ccgcgatggc aattccattt cgaaccagtt cgtcttcaaa
    23221 gcccgtaaac cagactgaca ggtaagtgta gtaatgactg gcaacaaaga aagcacaacc
    23281 ccatgtcacc agcgataacg cttcacgaac aaagccgcgg atcaggctaa ccagagagga
    23341 aaaagcaatc accgcgatta tggcgtaatc aatccagacc atatgtgtcc cacgatttta
    23401 cgccctgtca tcctgttcgg ggcgcattct aacagaaaaa gaaaacgttt gcgtagggat
    23461 ttccttcccg cgcatcaata aaaatggcgc tgaaaaaata ttcaacgcca tcgacttttt
    23521 atgcctttgc ggcatcgtgc aatgcgtgtc ggatgcggcg taaacgcctt atccgaccta
    23581 cggttctaac actgcccagg cctgataaga cgcgccagcg tcgcatcagg caagactgta
    23641 ttaattcggc gtatagccca ttaccacgcc acttaagcca gaaagttgct tcaactcacc
    23701 cagcgaacct ttcagcttat ctttcgaggc atccggccca accagaatac gggtaatttt
    23761 accctgcact ggcgtggatg gcgacgtata aacccgataa ccggcaccgc gcagcttacc
    23821 gacaatctca ttcactttat cggcattttt cagcgcaccc agttgcacaa cataggcttt
    23881 acccgttggc gctgcttttt cttccacgac cggcttcggt tctggcttcg gcgcaggtgg
    23941 tgcttcaacc ttcggtttcg gcggctccac cggtttcggc ttcggtgggg cgaccggtgc
    24001 aggttccggt tcaaactcgg tgttattggc tgcaatagtg gtcggatcga gcgacggtgc
    24061 tgcggcatca cctgcccgca cctcttccgc tgcgccttcc ggcggctgcg tcggcaacgc
    24121 ctgggtggcg gctggcatca tatcaggctc atcgcgatcg cccgctttcg gcaccagcgg
    24181 gatagccgcg aactcatcct gataatgttt tttctgcccg tccagcagcc ctggaagtac
    24241 aatcaccccc agcgccacca gcacgatcgt gcccactaac cgattctgaa acttacttgc
    24301 caccgcttct cctcgcgtca atcacttcca tgacatgtgc gacagtgtgg aaagaaccac
    24361 acaccagcac ggtgtcttcc gctttagcgt ccgccattgc ggcatcccat gcctgcgcaa
    24421 cgctatcaaa tgatttgccg ttacccaaat gctcaagcag ttgttctgcc gtggcaccgc
    24481 gcggcccttc cagtggcgca caataccagt catcaaccac gcttttcaac caggccagag
    24541 ttccggcaat atctttatca tgtagcatac cgataaccgc cagcacgcgc ccgtttttcg
    24601 gtagcgcttt catacgcccg gtgagatatt ccgccgcatg tggattatgc gcgacatcaa
    24661 aaataacgcg tggcgactcg ctcacaatct ggaaacgtcc cggcaaaatt gcgctggcaa
    24721 tcccgtcgcg aatggcattt tcactgactt ccagcccgct ggcacgcagt gccgccagcg
    24781 ccgttgcggc attcggttgc gggacaagcg gcaacggcag attttccagc gtgccgtgag
    24841 catcgctaaa cgcccagtca tgatcggtga cggaatagtt ccactcaacg ccccgacgtt
    24901 gtaacagtgc acctttttcc tgtgccacat cagcaatggt agaaggcatt tccggctcac
    24961 cgacaattgc cggtttttcg ctgcggaaga tgcctgcttt ctcgcgacca atactttcgc
    25021 gatctggacc cagccagtcg gtatgatcca gcgcaatact ggttactacc gcgacatcgg
    25081 catcgacaat attggttgcg tccagacgac cgcccagccc tacttccaga atcaccacgt
    25141 caagttgtgc ctgcttgaac agccacaacg ccgacagcgt accgtactcg aaataggtca
    25201 gggaaatatc accgcgtgcc gattcaatct ccgcaaaaga ggcggtgtgg gccgattccg
    25261 gcaattcctg gccctgcaca cgtacgcgct cggtataacg caccagatgc ggtgaactgt
    25321 agacgcccac tttgtaccct gccgccatca gaatcgactc cagcgtacgg caggtggtgc
    25381 ctttgccatt cgtacccgca acggtaaaca caaatggcgc tggtttcaga acgccaagac
    25441 gcgccgcgac ctgactcacg cgctcaaggc cgagatcgat agttttactg tgcaggtttt
    25501 ccagataaga aagccacgaa gccagaggcg acgcggcttg aggagtgcgt ttgataatca
    25561 tggtatccgc tgattcgtta cggtgagaat agcaaaaggg cagagccagt ggccctgccc
    25621 ttatcagtta tcaggcctca ggttcctgat ccggtaccgg gggtaccact acgccttcac
    25681 gcggcgcttc aggattcggc gctggcagat tcatcaactt cgccagaatg ctcgccagtt
    25741 tcaggcgcat ttccggacga cggacgatca tgtcgatcgc gcctttctcg atcaggaatt
    25801 cactgcgctg gaatccaggc ggcagttttt cgcgaacggt ctgttcgata acacgcggac
    25861 cggcaaagcc gattaacgct ttcggttcag cgatgttgag atcgcccagc atggcgaaac
    25921 ttgcagaaac accgcccatc gtcgggtcgg tcagcacgga gatgtacggc aagccgcgct
    25981 cctgcatttt tgccagtgcc gcagaggttt tcgccatctg catcagcgac atcagtgctt
    26041 cctgcatacg tgcgccacca gaggcggaga agcagatcag tgggcagtta tcttccagcg
    26101 cctgctcaac ggcacgcacg aaacgtgcac ccacaacaga ccccattgaa ccgcccataa
    26161 aggcgaactc gaatgccgca gcgacaaccg gcattccata cagagtgcct ttcatcacca
    26221 ccagcgcatc tttttcgcca gtttctttct gcgcagatgc cagacggtct ttatacttct
    26281 tggagtcacg aaacttcagc acatctttcg gctcaagctc gctacccagc tccacaaggc
    26341 ttccttcatc taacaggcta tgcaggcgat tacgcgctgt catacgcatg tgatggtcac
    26401 acttcggaca gacctcaaga ttacgttcca gctcagcgcg gtataaaacc tgaccgcagc
    26461 tatcacactt agtccacacc ccttcaggaa tgctcgcctt gcgggtggga gtaatgttgc
    26521 ttttaattcg ttcaatccag ctcattaggg acctttctgt ctgaacctgg ttcgatgcca
    26581 gttttatctt tggggacgca taatgccatt tttgccccca acagaccatg aatgttgcac
    26641 attaaaacat aacagcccga aactttggat aaaaaagtgg tcgaaccgcg gagttacttt
    26701 ttattttgcg gcgcgtgccg cagcgcgttt gtgacgaata aattcgaaaa ccccaggcaa
    26761 tattgaaaca aaaataatgc caacaatcat cagcttaagg ttgctctgaa tgaaggggag
    26821 cgtgccgaag aaataacccg cgtaggtaaa aatcagtacc cacaacagtg cgccgatcac
    26881 gttataagcg gcgaaatgac ggtacgacat gtggcccatt cccgcaacaa acggcgcgaa
    26941 cgttctgacg atcggtacaa aacgggcgag aataatcgtt ttgccgccat gtctctcgta
    27001 aaactgatga gtcttatcaa gataactgcg acgaaagatt ttcgaatctg gattactgaa
    27061 cagtttgtca ccaaataacc gtccaatggt gtagttcact gcgtcaccga caatagcggc
    27121 aatcaacatc agcacgacca tcatatggac attgagatcg ttagtttcca gtgacgccaa
    27181 tgcacctgca acaaacagca acgaatcacc aggcaggaat ggcgttacca ccagccccgt
    27241 ttcgcagaac agaatcaaaa acagaatggc ataaacccag acgccgtact ccgcgaccag
    27301 ctctgccaga tgcacgtcaa tgtgcaggat aaaatcgatg aggaaataaa tcaggtccat
    27361 atttgcctat gccttgtact cgtcatcttt caggctgtaa ctacgttggc tacagcctga
    27421 aatgttccga gcgttattct cgttagtccg ccagaaatag cgggcccatt ggcggttttg
    27481 gaagatcata ccggtcaggg taatccaccg cgaccagata cagcccttcc gcttttgccg
    27541 ttgctgccgc cagcgttctg tcctttgccg ccagcaactc tgctatccag ctctccggct
    27601 ggttgtgggc accgacttcc atcaggctgc cgacaatatt cctgaccata tgatgtacaa
    27661 aggcattcgc tttgatatct accaccacat aaggaccgtg acgcgtgaca ttaatatgca
    27721 taacgttgcg ccacggggtt cgggactggc actgcaccgc acggaacgag gtgaaatcat
    27781 tctcgcccag caagcattgc gcagcccgat gcatccgttc agcgtccagc ggttcgtaaa
    27841 aatgggttac ccctttactc agtaccgccg ggcgcagccg atgattgtag atgatgtagc
    27901 gataacggcg agccgtggcg ctaaatcggg catgaaaatc atcaggtaca gctttaaccc
    27961 aacgcacggc gatgtcacca ggtaaattcg catttacgcc caaggtccac gccgcgtctt
    28021 tgcgctgcgc ggtcgtttcg aaatgcacta cctgcccggt accgtgtaca ccagcgtcag
    28081 tacgcccggc gcagaagacg gtaatgggtt cgttcgccac ctgggagagc gccttttcca
    28141 gcttctcctg cacactgcgg acttcattct gccgttgcca gccgtaatac ttactgccgt
    28201 cgtactcaat gcccagcgca attttataaa ctggcggttg ttgctggtcg gacattagta
    28261 cagatactcc tgcaccagtt tctcggcgat ttttactgcc atcagcgcgc cgccaaagcg
    28321 aacgttatcg gccaccgacc agaactggac ttgctccggc ataccgtagt cattacgcac
    28381 gcagccaaca gaaagatgcg gcgtacccga agcatcccct acctgagtcg ggaattcgtt
    28441 ctcttcagag agcacaatat cttcgccctg agcaaacgca tcacgcgctt cttctgccgc
    28501 cagcggacgc agtgcttcaa agttgaccat ctgggcatga ccgtagaata ccggtgcctg
    28561 gacgacgctt gccgaaatca tcagcccttc gtcctgcagg attttgcgta cttcgtcaac
    28621 gatacgacgt tcttcacgca cgctaccttc gctatccggc aacaacggca gcatattgaa
    28681 cgccagttga cgaccgaaga aatcttcttc gtcaatcgga atgccgttga gcaatttcgc
    28741 actctgcccc gctaacgcat cgaccgcttt tttgccctgg gcggaggctg aaatcaggct
    28801 ggtaacactg atacgcgaca aaccgccctg atcgattaac ggtttcagtg ccgccagcag
    28861 ctggctggtc agactgtctg gtacggcgat gacattccgg ttgcggtaat cggtcagtac
    28921 aaacgggttt acttccggca ccaccagcgg tacgtcgggt tcgagagcaa acagtccgct
    28981 gctgtcgatc accaggcaac ctgagttggt cgcttcttca acccaggcag cggtagcttc
    29041 tttgcctgcg acaaaaaatg ccagctgcgc ctgcgtccag tcgaattcag cggcatcctg
    29101 cacggtgatt gttttaccac caaagcgcag ttgttcgcct gcgctttcgt tacgtgccag
    29161 tgcataaatt tccccaaccg ggaactgacg ttcagccagc gtttcaagca gggcttcgcc
    29221 cacagcgcca gttgcgccca ggacggcaat gttccagcct tcagacatgg tggtttactc
    29281 cagaaatagc aaagctccct gccaatgtta cagcagagag catgaagaag agattaacgt
    29341 gccggatgat gaacggcgtt aaaacccagt ttacacagca atgatgccgc actggcgtca
    29401 tcacaaatta catacagaga tgaccattca cggcgctcaa gatagttttt gcgcagttta
    29461 tcgaactcac ccggtatccc ggcgacttta cgcagcggtg cgtcatcgcg gcgcacatca
    29521 tacaccaaat gcaccagcct tttcagcgtc ggttgatcga gcgggccatg cagcgtaatg
    29581 cgaccaaact ctggcgcggg cagtaatgta tccagcgcaa cgtgctgttc atgcccaata
    29641 aacttgctat aggcttcaaa cacttgcgta gtaccgcgtg ctttaccttc cagggtataa
    29701 cctgcgatat gcggcgtgcc gatatccact tttgtcagca actccacgtt aagttccggt
    29761 tcgccttccc agacatccag cactacgctt aacttctggc cttcattcag gcaggtcagc
    29821 aacgcagtat tatcgacgac tgcgccacgg caggcgttaa tcagaatcgc tcccggcttc
    29881 aggctacgga tcagtttttc atccgccaga tgcagcgttt tgtacggccc atctttgaag
    29941 agtggcgtat ggaaagtcag aatatccgca tgctgaacta attcatccag cgagcggaaa
    30001 tcaccctcat ccccacggtc agcgcgaggc ggatcgcaaa gcaatgtttt aatccctaac
    30061 gcttccagtc gcgcctgcaa tcgacgtcca acgttaccaa cgcccacgat ccccaccgta
    30121 cggtcgtgca gtgaaaatcc atcgcgttcg gcaagcatca gtagtgagga gaaaacatat
    30181 tccaccaccg caatcgcatt acagccaggt gcagcggaaa aaccaattcc cgcctgcttc
    30241 aaccatgctt catcgacatg gtcggtcccc gcagtggcag tgccaacaaa tttaatgggt
    30301 tttcctgcca gcaaagattc attcactttc gtgaccgaac gcaccatcag cgcatccgcg
    30361 tctgccagtt gagcgacggg gattggacgc ccgggaaccg cggtcacctc acccaaacgg
    30421 ctaaataagt cgcgggcata aggcatattt tcatcaacaa ggattttcac gtttgtgtta
    30481 cctgtatgag acgagagtta accggacaag tgtgccataa tctcgcggcc aggcatactt
    30541 gcgaagattt caggtataag gatacgtaat gatacaacct atttccggcc ctcctcctgg
    30601 gcaaccacca ggtcagggag ataacctgcc gtctggcgcg ggcaatcagc ctttatccag
    30661 tcagcaacgt acttcgctgg aaagcttaat gacgaaagtg acctcactga cgcaacagca
    30721 aagagcagaa ctgtgggcgg gtatcaggca cgatattggt ctgtcgggag attcaccgct
    30781 gctttcgcgt cacttccctg ccgctgagca taatctggcg caacgtctgc tggccgcgca
    30841 aaaaagccat tctgcccgcc agcttttagc gcaattaggg gagtatttac gtctggggaa
    30901 taatcgtcag gcggtcacgg attatatccg tcataacttt ggtcagacgc cgctgaatca
    30961 gctctcaccg gagcaattaa aaaccattct caccctgttg caggaaggga agatggttat
    31021 tccgcaacca cagcagcgcg aggcgaccga ccgtccttta ttaccggcgg agcacaatgc
    31081 gctaaaacag ctggtgacca aacttgcggc ggcaacgggg gaacccagca aacagatctg
    31141 gcaatcgatg ctggaacttt ccggggtgaa agatggcgag ttaattccag cgaaactgtt
    31201 taaccatctg gtgacctggc tacaggcgcg tcagacgcta agccagcaaa atacgccgac
    31261 gctggaatca ctacagatga cgctaaaaca acctttagat gccagtgaac tggcggcgtt
    31321 atcggcatat atccagcaaa aatatggtct ttctgcgcaa tcatcgcttt cttctgccca
    31381 ggccgaggat attcttaatc agctttatca acggcgggtt aaagggattg atccgcgtgt
    31441 tatgcaaccg ctgcttaatc cttttccacc gatgatggac acgttgcaaa atatggcaac
    31501 gcgtcccgcg ctgtggatac tgttagtcgc gattatcctg atgctggtct ggctggttcg
    31561 ttaaccccga cgaaatgaca gtatcgtgac aataataccc agcaccgcag agatcgcccc
    31621 ggcaagaaat accgaagagt aaccaaacgt ggtcgccagc attcccgcca gcggcccgga
    31681 gacgccgagg gcgatatcct gaaacgcggc gtaaccgccc agtgcggtgc cgcgaacttg
    31741 tgaggggacg cgtttaacca cctccacgcc cagcgcagga aagataagcg aacatccggc
    31801 tccggttaac gccgcgcccg ctaatgcgac ccatgcacct ggggcttgcc agagcagcaa
    31861 caagcccacc gtttctacaa gcagagagac aatcgccact ttcacgccgc caaaacggtc
    31921 cggcatccag ccaaacatga cgcgcatcac gacaaatgcg ccgccaaacg cggtaagagt
    31981 aaagcccgcc atcgcccatc ctttgctggc aaagtagagc gaaacgaaag tcccgataac
    32041 agcaaaacca acgccttgta gtgccagacc taaccctggt ttccagataa gcccgacaac
    32101 gctccacagc gatggacgtt ctcccgccag ggccggtact ttgcgcactg tgccgttaca
    32161 ggcccacgcc agtacgggta ataccattgt ggtgatcgcc agtgcggcaa aaccgtaatg
    32221 gctatgaatc aacaggccaa gcggagcacc aacagcgagg gcaccgtaaa tcgccattcc
    32281 gttccatgac atcactttgc cagagtgttt tggccctacg atgcctagtc cccaggtcag
    32341 agcgcctgtc agtaactggc tttcaccaaa gccaagaatc aaacgcccga cgaccaacag
    32401 agcaaatttg aacggtgcgg agacaggcaa aatcgccgcc agcagcaacg cgccgccagc
    32461 cagaccacaa gctaacattc cctgaagcgc cgaacgtttt gcaccatatt gatcggccag
    32521 tcgcccggcg taaccacgcg tcagcaccgt agccagaaac tgaatcccga cggcaatgcc
    32581 gaccatggta ttgccatagc ccagttcatg atgaacaaac agcgggataa ccggcaacgg
    32641 caaccctacg gtcatgtagg tgagaaaaac cgcaaaagcg atgcggaaga gcgaaaaatt
    32701 ggcagaagat cgtgtttcgg tttggcttac agcagtcatg cattactcca gaatgcagcg
    32761 caaggcgagg agtatccccg tctcatctct ctggtttcag ggttacggtg cgttggcagg
    32821 atttaacgcg tacgtctttt cagaaggaaa tcgacaaagc gggaagtttg cctggaactg
    32881 gcggcgattg tcaatgatgt gaaaaaggga accatcaggt tcccttttgc gttagtgccg
    32941 gaggccgcat tggcgcgtaa cgtcggatgc gacgctggcg cgtctactcc gacctactgc
    33001 gaattaatct ttcagcttgc gcattaccag cgtggcgttg gtgccgccga agccgaagct
    33061 gttagacata acggtggtca gttcgcgatc ggtcgtttcg gtcacgatgt tcagacctgc
    33121 agcctgctcg tccagctctt caatgttgat gctcggggcg ataaagccgt gttccagcat
    33181 cagcagagag tagatagctt cctgtacgcc agcagcgccc agagagtgac cggtcatggc
    33241 tttggttgca gaaatcgccg ggctcttatc gccgaacact tcacggatag ctgccagttc
    33301 tttcacgtcg ccaaccggag tcgaagtacc atgagagttc aggtaatcga ttggggtatc
    33361 aacgccgtgc atcgccatct tcatgcagcg tactgcgcct tcgccagacg gagcaaccat
    33421 gtctgcacca tcagaggttg cgccgtagcc aacgatttca gcatagatgt gagcaccacg
    33481 cgccagcgcg tgttccagct cttcaaccac taccataccg ccgccgccag cgataacgaa
    33541 accgtcacgg tgagcgtcgt aagtacggga ggctttttcc ggggtgtcgt tgtatttagt
    33601 agacagcgca cccatcgcgt cgaattcgca ggccatttcc cagcacagct cttcgccgcc
    33661 gccagcaaac acgatgtcct gtttgcccag ttggatctgc tctactgcgt taccgataca
    33721 gtgtgcggaa gtcgcacacg cggagctgat ggagtagtta acgccatgaa ttttaaacgg
    33781 cgtggcgagg caggcagaaa cgccggatgc catcgctttg gtgaccacat acgggccaac
    33841 cgctttcagg ccgcgcgggc cgcgcattgc gtcagcgccg aacacctgga aacgcgggga
    33901 accgccgcca gaacctgcaa tcaggccaac gcgcgggtta ttctggtaag cttccggaga
    33961 aaggcccgca tctgcgattg cctgctccat agaaaggaat gcataaatgg atgcgtcgct
    34021 cataaagcgc acaactttgc ggtcaatgag gccagtggta tccagtttta cgttgcccca
    34081 gacgtggcta cgcatgccgg aatccttcag ctcctgagag aaagtgatcc ctgaacgtcc
    34141 ttcacgcaga gatgccagga cttcctgctg gttattaccg atgctggaaa caatgcccag
    34201 gccagtaatc actgcacgtt tcattcaata cctctgtaag tcgcacatag agtaagtttc
    34261 gaatgcacaa tagcgtacac ttgtacgccg aacaagtccg atcagccatt taatagagaa
    34321 atttgcgcag ccttacacac atcgctaaga tcgagccacc gcctgtaaga cgagtaactt
    34381 acgtgaaaca ctactccata caacctgcca acctcgaatt taatgctgag ggtacacctg
    34441 tttcccgaga ttttgacgat gtctattttt ccaacgataa cgggctggaa gagacgcgtt
    34501 atgtttttct gggaggcaac caattagagg tacgctttcc tgagcatcca catcctctgt
    34561 ttgtggtagc agagagcggc ttcggcaccg gattaaactt cctgacgcta tggcaggcat
    34621 ttgatcagtt tcgcgaagcg catccgcaag cgcaattaca acgcttacat ttcattagtt
    34681 ttgagaaatt tcccctcacc cgtgcggatt tagccttagc gcatcaacac tggccggaac
    34741 tggctccgtg ggcagaacaa cttcaggcgc agtggccaat gcccttgccc ggttgccatc
    34801 gtttattgct cgatgaaggc cgcgtgacgc tggatttatg gtttggcgat attaacgaac
    34861 tgaccagcca actggacgat tcgctaaatc aaaaagtaga tgcctggttt ctggacggct
    34921 ttgcgccagc gaaaaacccg gatatgtgga cgcaaaatct gtttaacgcc atggcaaggt
    34981 tggcgcgtcc gggcggcacg ctggcgacat ttacgtctgc cggttttgtc cgccgcggtt
    35041 tgcaggacgc cggattcacg atgcaaaaac gtaagggctt tgggcgcaaa cgggaaatgc
    35101 tttgcggggt gatggaacag acattaccgc tcccctgctc cgcgccgtgg tttaaccgca
    35161 cgggcagcag caaacgggaa gcggcgatta tcggcggtgg tattgccagc gcgttgttgt
    35221 cgctggcgct attacggcgc ggctggcagg taacgcttta ttgcgcggat gaggcccccg
    35281 cactgggtgc ttccggcaat cgccaggggg cgctgtatcc gttattaagc aaacacgatg
    35341 aggcgctaaa ccgctttttc tctaatgcgt ttacttttgc tcgtcggttt tacgaccaat
    35401 tacccgttaa atttgatcat gactggtgcg gcgtcacgca gttaggctgg aatgagaaaa
    35461 gccagcataa aatcgcacag atgttgtcaa tggatttacc cgcagaactg gctgtagccg
    35521 ttgaggcaaa tgcggttgaa caaattacgg gcgttgcgac aaattgcagc ggcattactt
    35581 atccgcaagg tggttggctg tgcccagcag aactgacccg taatgtgctg gaactggcgc
    35641 aacagcaggg tttgcagatt tattatcaat atcagttaca gaatttatcc cgtaaggatg
    35701 actgttggtt gttgaatttt gcaggagatc agcaagcaac acacagcgta gtggtactgg
    35761 cgaacgggca tcaaatcagc cgattcagcc atacgtcgac tctcccggtg tattcggttg
    35821 ccgggcaggt cagccatatt ccgacaacgc cggaattggc agagctgaag caggtgctgt
    35881 gctatgacgg ttatctcacg ccacaaaatc cggcgaatca acatcattgt attggtgcca
    35941 gttatcatcg cggcagcgaa gatacggcgt acagtgagga cgatcagcag cagaatcgcc
    36001 agcggttgat tgattgtttc ccgcaggcac agtgggcaaa agaggttgat gtcagtgata
    36061 aagaggcgcg ctgcggtgtg cgttgtgcca cccgcgatca tctgccaatg gtaggcaatg
    36121 ttcccgatta tgaggcaaca ctcgtggaat atgcgtcgtt ggcggagcag aaagatgagg
    36181 cggtaagcgc gccggttttt gacgatctct ttatgtttgc ggctttaggt tctcgcggtt
    36241 tgtgttctgc cccgctgtgt gccgagattc tggcggcgca gatgagcgac gaaccgattc
    36301 cgatggatgc cagtacgctg gcggcgttaa acccgaatcg gttatgggtg cggaaattgt
    36361 tgaagggtaa agcggttaag gcgaggtaat ctgctctcgc agtgtttgcc ggatgcggcg
    36421 tgaacgcctt atccgaccta cgtgtgacgt gtaggcctga taagacgcga taagcgtcgc
    36481 atcaggcatg gtgctccaga cgccgcaact tactgctgtg acgcctgctg aaacaggttt
    36541 tcccacatat cggtcaccag cgcctggtca cgcggcgaca attcaccggc accaatggct
    36601 ttttccagac tctggctaac ggtcgtatgc accgcctgag cggagtggtc atcaccactt
    36661 tccagttctg cgatggctaa tgtcaggtgg ccacgcaaat acccactggc aaacaactca
    36721 tcatcactgg catggtcaac cataccgtcg attaatgcca gaatgcgtga ttcaaactcc
    36781 gcgatcatct tctttcctca ttgtaaaacg tggcgctggc tttagttgag cgcttccggc
    36841 cacgggaact gttccgccgt aagttccggc gtgtgataat aattttgtag tgctttaatg
    36901 aagcgtgccg ggcgttcagg aatgccgttt gctaggtaat ccatcacctg cgcatgtacc
    36961 cgccgttgaa acaccacacg atccggttcg aagtcgcctt ccagattgtc gcaactgacg
    37021 ttaaacggat atcccgccgc cacacagaac aaccagtcga gtgcctgcgg cttcacttca
    37081 acatcttcaa actggctttg cgtttgggca tcacgcccat ccgggcaata ccagtagccg
    37141 aaatcaacca gctcacggcg cgcttttccg gcaatacacc agtgcgaaat ctcatgaatt
    37201 gcgctggcat aaaagccgtg ggcaaagaca attcggttat acggtacttc cgcatcagca
    37261 ggaagataga tcggttcgtc gtcgccttta atcagacggg tattaaattc atcggcaaag
    37321 cagctattaa aaatttcaat caactgctca tagtggtgtg tactgttcat tagttcatcc
    37381 ccaaccagtg gaggatctcc tgtccgtggc tatcgtaaag taatttggca ctcatcaccg
    37441 ccgagacgat aacaatcatc gggcggatca gcttttgtcc tttgctcaac accagccgtg
    37501 aacccatgcg cgcgccgagg aactgcccca ccagcatcac aaagcccgtc gcccaaatca
    37561 ctttgccgcc gagaataaac agcagcagac caccaatgtt tgacgttgcg ttgagtaatt
    37621 tggcgtgagc cgtggctttg gcgaggttga atccgcacag cgtaacgaag gccagcgcgt
    37681 aaaacgatcc ggcagccggg ccaaagaatc cgtcataaaa accgacgcag ccaccggcaa
    37741 ttaacgcgaa gggtaaaccg tacatccggc gctggcgatc ttcttcaccc agctttggca
    37801 tcagcaagaa atagaggccg atacaaatca ccagaatggg caaaatctgc cgtaagacat
    37861 cagcctgaac gtactgtacc aacagtgcgc cgctcattga gccgacaaag gtcatggcaa
    37921 tattgagttt ctgatcgctt aaactaacca ctttgcggcg aataaagtag atagtggcgg
    37981 aaatagagcc gccgcaggct tgcagtttat tggttgccag cgcattagcg ggagacatcc
    38041 ccgctgccat caatgccgga atggtgagta acccaccgcc accggcaatc gagtcgataa
    38101 atcccgccag catggcgaca aaaaagagaa ctcccagcaa cagcggggaa accataaaca
    38161 ggctattaaa cgtttccatt agatcacgtg ctcatccagt agcgcctggc aggaaggcgg
    38221 caacggagac ggtgtcttct tctcaggctt tgttgttccc ggttttggag gtgcaaacca
    38281 gctttgcagt tctgccccgc aaccatcgcc tggtggcggt aaaggttgat cttcacactc
    38341 cagactatcg gcaggacaac gtaatcgtac atgcatatgc gcgcgatgct ggaaccaggg
    38401 tcgcactttg cgcaaccagt cgcgatcggt gcccgcatca aggcaaagtt gttgtttaat
    38461 cgccggatta acaaaaatgc gtgtgacgtc tttgtcctgg gcggcgagtt tgatcaagct
    38521 gaaaatttct ggcttccaca gcgtggagac aacgtgttta ccgtcgcggg aaactaagtc
    38581 cagtgcttgc gggcgcaaga gctgcgcgga ggtccagcga gttttcggca gttgcagaaa
    38641 gatatcgaca tccagtccgg tctggtggct ggcatgaccg ccgttgaaac gcccaccagc
    38701 gggcatcccc atatcgccaa tcagcaccgt acccatgccc agattgctca cctggctact
    38761 cagacgctgg ataaacatca ccagatccgg gtgaccgaaa tagcgacgct gatcggtacg
    38821 catgacctga taatgttcgg actgtatcgg cagcgtgtca gcaccgacga tacagccatt
    38881 agaaaaactg cctatcgatt gtgcgctacc cggcacaggt tgggttattt tttgccacgg
    38941 cgtcgctgcc aggctagcgc tactggcaag cagagccagc agcgcaatcg cggttttgtt
    39001 cattttttac cagcgtggaa tatcagtctt cacatcggca ttttgcgccc gctgccgtaa
    39061 caggtgatcc attaaaacga tcgccagcat cgcttcagcg atcggcactg cacggatccc
    39121 gacacaggga tcgtgacggc ctttggtgat catctcaact tcttcgccaa agcggttaat
    39181 agtgcgcccc ggcacggtaa tgctggaggt cggtttcagc gccatatgag caatgatttg
    39241 ctgcccgctg ctgataccgc cgagaatgcc gcccgcatgg ttgctctgga aaccgtcttt
    39301 ggtgatttcg tcgcggttct ggctgccgcg cagcgccact acgtcaaaac cgtcgccaat
    39361 ttccacgcct ttcaccgcgt tgatgctcat cagcgcatgg gcgatgtcgg catccaggcg
    39421 gtcaaagacc ggctcgccaa gtccggcggg gacaccactg gcaacaacgg tgactttcgc
    39481 gccgatggag tcgccctctt ttttcagcgc gcgcatcagt tcatctaacg cgtcgatttt
    39541 gtcggggtcc gggcagaaga acggattttg ttcaaccagc gaccagtctt tgatttccag
    39601 cggaatgtcg cccatctggg tcaagcagcc gcggatttca ataccaaatt tctcggcgag
    39661 atattttttg gcaatcgccc ctgccgccac gcgcatggcg gtttcgcggg cggaagaacg
    39721 tccaccgccg cgataatcgc gcagaccgta tttttgttcg taggtgtaat cagcatggcc
    39781 tgggcggaaa acgtctttaa ttgcgctgta atcctgagag cgctggtcag tgttttcgat
    39841 caacaagcca atgctggtgc cagtagtaac gccttcaaaa acaccggaga gaattttgac
    39901 ctgatccggc tcgcggcgct gggtggtata gcgcgatgtc ccagggcgac gacggtcgag
    39961 gtcatgttgc aggtccgctt ccgtcagcgg aatgcctggc ggaacaccat cgacgatgca
    40021 gccgagcgcc agcccatgcg attcgccgaa ggtggttacg cgaaagagtt gtccaattgt
    40081 gtttccagcc atcacggctc cgttattgtt gtgtttgcgt gtttacttaa tctttataaa
    40141 tcgcgaaata ttcacgggcc gccagcagct gctctttggt gagcataaac acaccatcgc
    40201 cgccgttatc aaactccagc caggtgaacg gaacatccgg atattgttcc ataagatgta
    40261 ccatgctgtt gccgacttca caaatcaaca cgccatcatc agcaaggtaa tctgccgcgt
    40321 ttccaagaat gcgacgtgtc agtttaaggc cgtcggtgcc agatgccagg cccagttccg
    40381 gctcgtgacg gtattcgttt ggcaggtcgg acatatcttc cgcgtcgaca tacggcgggt
    40441 tagtgacaat cagatcgtat tgcactttcg gcaaatcacg gaacagatcg gaacgaatcg
    40501 gaatgacgtt gtggatcaga ccgtgttctt cgatgttctg ttcggcaacc gccagcgcgt
    40561 cgggagagat atctaccgcg tcgacttccg cttccgggaa ggcataagca caggcaatgg
    40621 cgatgcagcc gctaccggta cacatatcta aaatatgctg cggttgcttg ctgatgagtc
    40681 cggcaaattt attgttgatc agttcaccaa tcggcgagcg cggcaccagc acgcgttcat
    40741 cgacgtaaaa ttcatgaccg cagaaccagg ctttgttggt caggtaagcc accggaatgc
    40801 gctcgttgac gcggcggatc acgcgttcaa caatacggtg tttttcgctg gaggtcagac
    40861 gcgcggtgcg catatcttcc gggatatcca gcggcaggta gagcgatggt aacaccagct
    40921 gtacggcttc atcccacggg ttatcggtgc cgtgaccgta ccagatattt gccgcgctga
    40981 agcggcttac cgaccagcgc aacatgtcct gaatggtttg cagctcattt actgcttcat
    41041 caacgaaaat tttatccacg tattcctcca gggcatgatc gcaataattt cggcggctag
    41101 tttgccatga agatgacgat aaatcagcat tcacgcgcgg tgagtgagga aaaatacgtt
    41161 taaaacgatc gattgtgcta cgagtcgggt aaactgtagg aaaattagaa atagagacag
    41221 ataaatgaaa aagaaaacaa cacttagcga ggaggaccag gctctgtttc gccagttgat
    41281 ggcggggact cgcaagatta agcaggacac gattgtccac cgaccgcagc gtaaaaaaat
    41341 cagcgaagtg ccggtgaaac gcttgatcca ggagcaggct gatgccagcc attatttctc
    41401 cgatgagttt cagccgttat taaataccga aggtccggtg aaatatgttc gcccggatgt
    41461 cagccatttt gaggcgaaga aactgcgccg cggcgattat tcaccggaat tgtttttgga
    41521 tttacacggt ctgacgcagc tgcaggccaa gcaggaactg ggcgcgttga ttgccgcctg
    41581 tcgccgcgaa catgtgtttt gtgcctgcgt gatgcatggg cacgggaagc atattttgaa
    41641 gcaacaaaca ccgctgtggc tggcacaaca tccgcatgtg atggcatttc accaggcacc
    41701 gaaagagtac ggcggtgatg cggctttgtt ggtgttgatt gaagtggaag agtggttgcc
    41761 gccggagttg ccctgaggag ttgagcgtgt tgtgccagga gcgcggaatg gcaggggcga
    41821 atgaccctgc caggtgagaa aaggtgcgct aatacatatt cagtatgtaa gtgaatcggc
    41881 aggtagaatc tatgggctgt cgagatgtcg tgtccacgcg tagcttcata tcatgcagtt
    41941 gcctggacgt gatcggttgc ggctctggcg tcaccgtcac tttggcatta tcacagccgg
    42001 aagtcgagaa ggtcatctgc tgtgcgacaa aacggcagta ggctccacgc tcgtcaaaat
    42061 tactgccatc acacagtttg ccgttttcca tcaggaaagt gggcagtgtt tgctcaataa
    42121 caccacctgt tgactgcaac ctgacgactt tgttatgtac aacataattt tcattccagg
    42181 aaacatcata cggtgccagg gactctgtcg ggcagtcaga gctaactttt gttggtccta
    42241 taaaaattcc ggccccgaaa cgctgatcca tagtactggc gctttcaaca taagacgaca
    42301 caatccaggg acaaccgtgt aaatctccat cgtaataaac gccaagtact aattcattac
    42361 atgaccaggc cgttactgga gagagagcat catactcttc taatccgggg caggtagaat
    42421 ccggtaaggt tgtattattg cgctccatcc tgagttcagg gccgggagga ctcccggtcc
    42481 aactaactaa aggcaaactt gctgccgcag ttgaattaga ttcatacgtg ccatattcaa
    42541 ctgattgagg ggtcaggact gaaagatgaa aacgatactt tgcaacaacg ctggtcgtcc
    42601 ccgcgggtac atagagtgtg gcgatctttg tcgcagcctg tatcccagaa gcgcacagag
    42661 ccagcaccaa taaacatata acatgacgta ttttatgcat tttatatata ctcaaacgta
    42721 gctgtcaggc tggcggtgaa atcaccgatg gttacatcac gaccgctttt cgcctggatc
    42781 caggcccgga aattaatatc attgttgccg ttggtaagcg caaaggtcgc cccggtggtg
    42841 ttgttaatat ccacccgctt gccgtcgagc gtttccatcc ctatccccac gccctgcgcg
    42901 gtggaggtgt catcgactgc cagaaaaccc ggctgaccgc tgtcttcggt gccgctcagc
    42961 gtgactttga cgttgtatcc cgccggccct ttgcagtctt tcagcttaaa cacaaccggc
    43021 agatgcgcgg actgcccaga taccatcaaa tcccggttgc tgacggtggg aaaatggatt
    43081 tctgccaggt tggcaccatc caccaccagc gtgcaggatt tactcagcag gttgccgtaa
    43141 aaatgcaggt tgttgtcgac tgcctgagct cctgtgctgg cggtcagcag caggcctgct
    43201 aacagcgcat aaccgggtga ataaatgtgt gctgttttca ttggtaatcc acccgtaagg
    43261 ttgcgtaagc agaaaaggtc gtgtccgtca gcaccgcatc agccgctttg accggtaccg
    43321 cctccagctt tggcttctgg ctaaaatcgg tggcgttaat ggaaagcggc tcgttgagct
    43381 taaaacgctg accgtcatgc tgaagctcaa ttccgaagcc cggtacatcc gtctcaatag
    43441 cagagtcgtt gtaggaggtg gcagtccccg tccaggagag tgtcatattc cactcgggat
    43501 cgcggacatc cgagtcgcag ctcagttcgt agtccacttt ctgacgacca taattgccat
    43561 caatgctgtc gataatgaga tcgcgaaatt gcacttcgat ggtttgcccg ccgctgatgc
    43621 tacaggcggg cggcgacatc agcgtaccgt ggaatgtgat gtcatcttcc gccgccagca
    43681 cagccccgca accagcgcac agtaaaagga gcaggaattt tttcattggt aatccaccac
    43741 catggtcatc gtggcgttaa actccgacgg cgtcagttgc accccgctct gttttaccgg
    43801 caccgctttc agctgaggct gagtgttgac attaaaaggc gtccagttat tttcaccaac
    43861 tgcaaacagg gagttgtcgg cggcgttttc tatccgcacc cccaggccgg cgatatccgt
    43921 gctgagaacc gtttctccgt tgatcacggc ggtattgcct ttgagctgca tccgtaagtc
    43981 atcgctgact ttattaccgc agttgagggt gtatttcgca tcctgttggt aattggtacc
    44041 atcgatcctg ttgattatca cattgccaaa tttcacagcg cttcccttca cggagcaagg
    44101 cggcggtcca tcgaccagga ttcgcagcgt cagatccacc tgtttgatat cactgccagc
    44161 aacagccaaa ccgctgatgc cccatccggc cagcaccagc aaccctgcgc ccgctacaaa
    44221 cttgtgactc ataagtccct cccggcatca gcctttgcgg ctctgctctt catccacctg
    44281 gcagctgttg ccggtgcata tgaagtacag cggcatccgc gcgccgtagt cgttgatgta
    44341 agtcagcacc ggcacgctgt ccatcttcgc attcagcggt gcggaggttt tcggctccat
    44401 catcagcggt gtgaatcccg ccggcgggtt gccgcctttt ttagcgctgg cgttgctgat
    44461 gatcacgtag tacggcgtcg ggttattgac ggtgaagtcc tggccgttac ggatgagcgt
    44521 caccttatgc tgccacggac ttttcatgct ggtgttctcc agcgccttcg gtcgccagaa
    44581 cagtttgata cgcgtctgca gcgcaatctg cagtgtgttc ggtttatttg atttcggcgg
    44641 aatttcgcgc acgttgaaat agaacacgct ctcgcggtcg gccggcagtt tgttgatatc
    44701 cggcagcccc tgcaccttca cctggccgtt catcatcgca tcgatgcgct gcactggcgg
    44761 aagcaccgca agcggcgagc tgattttgtt gccctttgca tcctctatcc agctctgcgc
    44821 cagataaggc agtgtgggat cgttgttgcg cagcgtgacg ctgatggact tgtcgctttc
    44881 gttaaacacc agccgtgtcc tgtcgggcgt caccgaagcg tggctggaga aactgaccgc
    44941 tgtcgccagc agcgccagtg ccgggacaac gatttttgca gtgttagtca gattaaacat
    45001 ggatcattcc ttaatcacgt tactggttta ctgaaattga agtcggaggt tccgttggcg
    45061 tcacccgctg tgtctgttcc tgaatcgccg gtttgaccgc cggcgaagtg ataggtgcta
    45121 cattgccttt atgctggcat ggcagtaaca agccgttaaa cagatcggca ggcagcgggt
    45181 ccggcaggtt gatatcgcaa tgcgcaacac cactccagaa cacactcatg tgttcgccag
    45241 gtttcacccc agccagataa acattgccgt catcatcgac aaggcccact gtctgctcgt
    45301 tatcattttt tacttctgcg ccaaacggag gatggctgcc gtcgctcagg cgcagcaccg
    45361 ccatcgcttt ttgtccgcta atgacagcaa atttacggta gccaatggca ccttcagtta
    45421 gcgtggcttg caccaccgac tgggttgctt cagcgttttc aggcaatctg ttgaggtcga
    45481 tatacgcctg attgcggtaa tagttattga cgtcagaaac gacggcttta ccaaacatat
    45541 tggtataaac agcagccccg ttaccttcca ccggaacatc ggcaacgcca tcggcatcaa
    45601 tcaacaagcg tgtcccgccc atattctggg tacggtgaag tgcgccaccg tgggcagtaa
    45661 gcgttgcgcc gccctgtaac gacaagcccg cagaggtgta ttgcccttca tggtagttcg
    45721 cactgaagtc aacctgcgcc agcgaaccat catggctgta atagccgtca acgctggtgt
    45781 gtttgtcact ggtgccgacg ttcaactgat agtgagtcgc gtcatcgaca cggctgaaat
    45841 aaccgacctg actgctgtcc gtcccactgc catagttacc gttatagcta acggtactgt
    45901 tgtcgcccca cggcatactg agcgaaatgt acatgccttt gtcggcctgg ttgtcatact
    45961 cgtaacggta gccagtcatc gagatgctga cattacgaat actgcccata ttgaaatagt
    46021 gcgagagcat gatgttgtag tttgtctgct cctcgcgatc ccagtaggta tggcgggtat
    46081 agttgagata aaccgaaaca cccgcatcgc ggaagttctg gttataagtg gcggtgtaca
    46141 tctctttgtc gttgcccgtg cgtaccattc cgctgtcact ggcatccaga tactcgctca
    46201 tggtcataaa gttctcttcc gagaagcgat atccagcaaa agtaacgcgg ctgttgagct
    46261 ggtcaaagtc tttggaataa ctcacacgga aggagttacc gtccagcgaa cctttgccat
    46321 aagcggtgtc tttatccagt ttggtgtgcg agtgagtaac atcaaacgcg accgcgccga
    46381 atgtagacaa atcgcgaccg acgccaagcg ccgcagactg atagttttca tctcccagtg
    46441 cgccgccata taacgaccag ccgttagcga tcccccagga agcttcagca ccagaaaaaa
    46501 attcaccctc gacatggtgt ccccactctt gcggacggcc catcatgatc ttatagcgaa
    46561 cctgacctgg gcgagtgagg tatggcatcg aggcggtgct gatgtcatat tcctgcacct
    46621 ggccgttctg ttcttcaatg cgaatatgca acgtaccgga gacagaatca ccaagatcct
    46681 gaatacgaaa cggtccagcc ggaacctgcg tttcgtaaat cacacgcccc atctggctga
    46741 cggtcacttt tgctgtggtg tgtgccacgc cggaaatgtc tggcgcgtag ccgcgcagat
    46801 tgggaggcaa catttgatcg tcagtactga cactgccacc aacatagtta aaaccatcaa
    46861 aaatatcgga tctgaggtaa tcctcgccca gcgccagttt ggcttttaat gatggtaacg
    46921 cccgccaggc atagtagcga ctccactccc attttttttg agtttcatcg ccgctgaatt
    46981 catcgtcatc attactgcga gtatgttgat agttagtctg ccagtcagca cgcatacgcc
    47041 acggccccag gttaaccccg accgtcccgt tgccgctgat ctcgttacta tcatcaccgc
    47101 cattttcttc gtgccgggtt tgtgcgttga tgctgtagtc cgcgacgatc ccggagatgc
    47161 cgtcatccca acgtgaaggc ggatcccagt cgggataagt atattcgagg taagcctgtg
    47221 gcagtgaaat gactaatgcg gactggctta aatcagcctt aatttccatg ccttccagtt
    47281 gaccggattt caggcattta gcatcgtggc tccattgcag atttttcgcc acgtcttctt
    47341 ttaaaccaaa ctgcgctacc agttccggtg tcagacaagc atagcttttg ctcgcgtcat
    47401 cttcaccagc ataccagtaa atatcgtact cttccgccaa tggctgttta tttagttgaa
    47461 cctgtaaatt gtattttccg ggctcaacat atccctggct ggaaaaacgc ttcagatcaa
    47521 tttttgtgtc gccttttaat tccagaaaac gggaatcaaa ctgaatgtcg tcttcagccc
    47581 agacactgct ataactccct gacattgcca gcgcaatgca ccacggaaga atccgtaatc
    47641 gaaaaagaga atggtcaggc atacacgttt ctatccgttt ttattcttgt tcggtcaaaa
    47701 tccatttaaa tcccccatag cagtgtcgct atgggggtat gccttacagg taagtaatct
    47761 ggaaggtggt atttgcttcg aaattaccca gatctggcgc atcagctgcg ccgaccagcc
    47821 aggctttaaa gttcagtgtc tgcttcgctt tgcctttatt ggtagaagtg tctttcacta
    47881 ttttctggtc aatacccatg ccgcttttgt aagaggtacc cagagagtca ccgatcgcta
    47941 ggctaacatt gttaaatgcc gcaccggtat cggtattgaa aatggtgtaa taattgccgc
    48001 tatttgcaga agaaacggta ccagtaaagg tagtggtcat tgtttcctga gtatcaaata
    48061 cgcaatcttg cagacgaatc tggaaacttt tcggcgtggt ggtgccgtta tttttcagtt
    48121 tttcggcacc gatatcaccc atatcaactt ccagtttgtg atcgtccgga acgatagaac
    48181 acactgagtc ttcaatggtg ccgtaaaaac gtgcagtacc gttgttaacc gcagcgattg
    48241 ttgccgtaga ggtgaaaacg cccatcacca ttgccgcagc aatagctgtt ttaacaaact
    48301 t
//
LOCUS       DAPOAV010000028        47264 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.028, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000028 DAPOAV010000000
VERSION     DAPOAV010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 47264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47264
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.028"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            112..2340
                     /gene="crfC"
                     /locus_tag="RN951_001841"
     CDS             112..2340
                     /gene="crfC"
                     /locus_tag="RN951_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="clamp-binding protein CrfC"
                     /protein_id="HDX2526849.1"
                     /translation="MYTQTLYELSQEAERLLQLSRQQLQLLEKMPLSVPGDDAPQLAL
                     PWSQPNIAERHAMLNNELRKISRLEMVLAIVGTMKAGKSTTINAIVGTEVLPNRNRPM
                     TALPTLIRHTPGQKEPVLHFSHVAPIDCLIQQLQQRLRDCDIKHLTDVLEIDKDMRAL
                     MQRIENGVAFEKYYLGAQPIFHCLKSLNDLVRLAKALDVDFPFSAYAAIEHIPVIEVE
                     FVHLAGLESYPGQLTLLDTPGPNEAGQPHLQKMLNQQLARASAVLAVLDYTQLKSISD
                     EEVREAILAVGQSVPLYVLVNKFDQQDRNSDDADQVRALISGTLMKGCITPQQIFPVS
                     SMWGYLANRARYELANNGKLPPPEQQRWVEDFAHAALGRRWRHADLADLEHIRHAADQ
                     LWEDSLFAQPIQALLHAAYANASLYALRSAAHKLLNYAQQAREYLDFRAHGLNVACEQ
                     LRQNIHQIEESLQLLQLNQAQVSGEIKHEIELALTSANHFLRQQQDALKVQLAALFQD
                     DSEPLSEIRTRCETLLQTAQNTISRDFTLRFAELESTLCRVLTDVIRPIEQQVKMELS
                     ESGFRPGFHFPVFHGVVPHFNTRQLFSEVISRQEATDEQSTRLGVVRETFSRWLNQPD
                     WGRGNEKSPTETVDYSVLQRALSAEVDLYCQQMAKVLAEQVDESVTAGMNTFFAEFAS
                     CLTELQTRLRESLALRQQNESVVRLMQQQLQQTVMTHGWIYTDAQLLRDDIQTLFTAE
                     RY"
     gene            2337..3215
                     /locus_tag="RN951_001842"
     CDS             2337..3215
                     /locus_tag="RN951_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418534.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjcZ-like family protein"
                     /protein_id="HDX2526850.1"
                     /translation="MTKTLLDGPGRVLESVYPRFLVDLAQGDDARLPQAHQQQFRERL
                     MQELLSRVQLQTWTNGGMLNAPLSLRLTLVEKLASMLDPGHLALTQIAQHLALLQKMD
                     HRQHSAFPELPQQIAALYEWFSARCRWKEKALTQRGLLVQAGDQSEQIFTRWRAGAYN
                     AWSLPGRCFIVLEELRWGAFGDACRLGSPQAVALLLGDLLEKATQHLAESINAAPTTR
                     HYYHQWFASSTVPTGGEHADFLSWLGKWTTADKQPVCWSVTQRWQTVALGMPRLCSAQ
                     RLAGAMLEEIFSVNLA"
     gene            3479..4981
                     /gene="proP"
                     /locus_tag="RN951_001843"
     CDS             3479..4981
                     /gene="proP"
                     /locus_tag="RN951_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline transporter ProP"
                     /protein_id="HDX2526851.1"
                     /translation="MLKRKKVKPITLRDVTIIDDGKLRKAITAASLGNAMEWFDFGVY
                     GFVAYALGKVFFPGADPSVQMVAALATFSVPFLIRPLGGLFFGMLGDKYGRQKILAIT
                     IVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGGEYTGASIFVAEYSPDRK
                     RGFMGSWLDFGSIAGFVLGAGVVVLISTIVGEANFLDWGWRIPFFIALPLGIIGLYLR
                     HALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKYWRSLLTCIGLVIATNVTYY
                     MLLTYMPSYLSHNLHYSEDHGVLIIIAIMIGMLFVQPVMGLLSDRFGRRPFVLLGSVA
                     LFVLAIPAFILINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIRYSALAAA
                     FNISVLVAGLTPTLAAWLVESSQNLMMPAYYLMVVAVVGLITGVTMKETANRPLKGAT
                     PAASDIQEAKEILVEHYDNIEQKIDDIDHEIADLQAKRTRLVQQHPRIDE"
     gene            5093..5182
                     /gene="pmrR"
                     /locus_tag="RN951_001844"
     CDS             5093..5182
                     /gene="pmrR"
                     /locus_tag="RN951_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LpxT activity modulator PmrR"
                     /protein_id="HDX2526852.1"
                     /translation="MKNRVYESLTTVFSVLVVSSFLYIWFATY"
     gene            complement(5158..6258)
                     /gene="pmrB"
                     /locus_tag="RN951_001845"
     CDS             complement(5158..6258)
                     /gene="pmrB"
                     /locus_tag="RN951_001845"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PmrB"
                     /protein_id="HDX2526853.1"
                     /translation="MNLMHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQI
                     QLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLTLFICYQAVRRITRPLAELQ
                     KELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTP
                     LAGVRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLE
                     DVILPSYDELSTMLDQRQQTLLLPESAADITVQGDATLLRMLLRNLVENAHRYSPQGS
                     NIMIKLQEDDGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGLGLSIVSRITQL
                     HHGQFFLQNRQETSGTRAWVRLKKDQYVANQI"
     gene            complement(6259..6927)
                     /gene="basR"
                     /locus_tag="RN951_001846"
     CDS             complement(6259..6927)
                     /gene="basR"
                     /locus_tag="RN951_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BasR"
                     /protein_id="HDX2526854.1"
                     /translation="MKILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEAGH
                     YSLVVLDLGLPDEDGLHFLTRIRQKKYTLPVLILTARDTLTDKIAGLDVGADDYLVKP
                     FALEELHARIRALLRRHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR
                     LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVA
                     NEEN"
     gene            complement(6924..8567)
                     /gene="eptA"
                     /locus_tag="RN951_001847"
     CDS             complement(6924..8567)
                     /gene="eptA"
                     /locus_tag="RN951_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418538.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase EptA"
                     /protein_id="HDX2526855.1"
                     /translation="MLKRLLKRPSLNLLAWLLLAAFYISIYLNIAFFKQVLQALPLDS
                     LHNVLVFLSMPVVAFSVINIVLTLSSFLWLNRPLACLFILVGAAAQYFIMTYGIVIDR
                     SMIANIIDTTPAESYALMTPQMLLTLGFSGVLAALIACWIKIKPATSRLRSVLFRGAN
                     ILVSVLLILLVAALFYKDYASLFRNNKELVKSLSPSNSIVASWSWYSHQRLANLPLVR
                     IGEDAHRNPLMQNEKRKNLTILIVGETSRAENFSLNGYPRETNPRLAKDNVVYFPNTA
                     SCGTATAVSVPCMFSDMPREHYKEELAQHQEGVLDIIQRAGINVLWNDNDGGCKGACD
                     RVPHQNVTALNLPDQCINGECYDEVLFHGLEEYINNLQGDGVIVLHTIGSHGPTYYNR
                     YPPQFRKFTPTCDTNEIQTCTKEQLVNTYDNTLVYVDYIVDKAINLLKEHQDKFTTSL
                     VYLSDHGESLGENGIYLHGLPYAIAPDSQKQVPMLLWLSEDYQKRYQVDQNCLQKQAQ
                     TQHYSQDNLFSTLLGLTGVETKYYQAADDILQTCRRVSE"
     gene            complement(8671..10008)
                     /gene="adiC"
                     /locus_tag="RN951_001848"
     CDS             complement(8671..10008)
                     /gene="adiC"
                     /locus_tag="RN951_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine/agmatine antiporter"
                     /protein_id="HDX2526856.1"
                     /translation="MSSDADAHKVGLIPVTLMVSGNIMGSGVFLLPANLASTGGIAIY
                     GWLVTIIGALGLSMVYAKMSFLDPSPGGSYAYARRCFGPFLGYQTNVLYWLACWIGNI
                     AMVVIGVGYLSYFFPILKDPLVLTITCVVVLWIFVLLNIVGPKMITRVQAVATVLALI
                     PIVGIAVFGWFWFRGETYMAAWNVSGLGTFGAIQSTLNVTLWSFIGVESASVAAGVVK
                     NPKRNVPIATIGGVLIAAVCYVLSTTAIMGMIPNAALRVSASPFGDAARMALGDTAGA
                     IVSFCAAAGCLGSLGGWTLLAGQTAKAAADDGLFPPIFARVNKAGTPVAGLIIVGILM
                     TIFQLSSISPNATKEFGLVSSVSVIFTLVPYLYTCAALLLLGHGHFGKARPAYLAVTT
                     IAFLYCIWAVVGSGAKEVMWSFVTLMVITAMYALNYNRLHKNPYPLDAPISKD"
     gene            complement(10145..10906)
                     /gene="adiY"
                     /locus_tag="RN951_001849"
     CDS             complement(10145..10906)
                     /gene="adiY"
                     /locus_tag="RN951_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator AdiY"
                     /protein_id="HDX2526857.1"
                     /translation="MRICSDQPCIVLLTEKDVWIRVNGKEPISLKANHMALLNCENNI
                     IDVSSLNNTLVAHISHDIIKDYLRFLNKDLSQIPVWQRSATPILTLPCLTPDVFRVAA
                     QHSMMPAETESEKERTRALLFTVLSRFLDSKKFVSLMMYMLRNCVSDSVYQIIESDIH
                     KDWNLSMVASCLCLSPSLLKKKLKSENTSYSQIITTCRMRYAVNELMMDGKNISQVSQ
                     SCGYNSTSYFISVFKDFYGMTPLHYVSQHRERTVA"
     gene            complement(11231..13498)
                     /gene="adiA"
                     /locus_tag="RN951_001850"
     CDS             complement(11231..13498)
                     /gene="adiA"
                     /locus_tag="RN951_001850"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418541.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine decarboxylase"
                     /protein_id="HDX2526858.1"
                     /translation="MKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDG
                     FAILSSNEAIDCLMFSYQMEHPDEHQNVRQLIGKLHERQQNVPVFLLGDREKALAAMD
                     RDLLELVDEFAWILEDTADFIAGRAVAAMTRYRQQLLPPLFSALMKYSDIHEYSWAAP
                     GHQGGVGFTKTPAGRFYHDYYGENLFRTDMGIERTSLGSLLDHTGAFGESEKYAARVF
                     GADRSWSVVVGTSGSNRTIMQACMTDNDVVVVDRNCHKSIEQGLMLTGAKPVYMVPSR
                     NRYGIIGPIYPQEMQPETLQKKISESPLTKDKAGQKPSYCVVTNCTYDGVCYNAKEAQ
                     DLLEKTSDRLHFDEAWYGYARFNPIYADHYAMRGEPGDHNGPTVFATHSTHKLLNALS
                     QASYIHVREGRGAINFSRFNQAYMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEV
                     IDEAVDFRQAMARLYKEFTADGSWFFKPWNKEVVTDPQTGKTYDFADAPTKLLTTVQD
                     CWVMHPGESWHGFKDIPDNWSMLDPIKVSILAPGMGEDGELEETGVPAALVTAWLGRH
                     GIVPTRTTDFQIMFLFSMGVTRGKWGTLVNTLCSFKRHYDANTPLAQVMPELVEQYPD
                     TYANMGIHDLGDTMFAWLKENNPGARLNEAYSGLPVAEVTPREAYNAIVDNNVELVSI
                     ENLPGRIAANSVIPYPPGIPMLLSGENFGDKNSPQVSYLRSLQSWDHHFPGFEHETEG
                     TEIIDGIYHVMCVKA"
     gene            complement(13697..14605)
                     /gene="melR"
                     /locus_tag="RN951_001851"
     CDS             complement(13697..14605)
                     /gene="melR"
                     /locus_tag="RN951_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator MelR"
                     /protein_id="HDX2526859.1"
                     /translation="MNTDTFMCSSDEKQTRSPLSLYSEYQRMEIEFRAPHIMPTSHWH
                     GQVEVNVPFDGDVEYLINNEKVNINQGHITLFWACTPHQLTDTGTCQSMAIFNLPMHL
                     FLSWPLDKDLINHVTHGMVIKSLATQQLSPFEVRRWQQELNSPNEQIRQLAIDEIGLM
                     LKRFSLSGWEPILVNKTSRTHKNSVSRHAQFYVSQMLGFIAENYDQALTINDVAEHVK
                     LNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKSILDIALTAGFRSSSRFYS
                     TFGKYVGMSPQQYRKLSQQRRQTFPG"
     gene            14888..16243
                     /gene="melA"
                     /locus_tag="RN951_001852"
     CDS             14888..16243
                     /gene="melA"
                     /locus_tag="RN951_001852"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HDX2526860.1"
                     /translation="MMSAPKITFIGAGSTIFVKNILGDVFHREALKTAHIALMDIDPT
                     RLEESHIVVRKLMDSAGASGKITCHTQQKEALEDADFVVVAFQIGGYEPCTVTDFEVC
                     KRHGLEQTIADTLGPGGIMRALRTIPHLWQICEDMTEVCPDATMLNYVNPMAMNTWAM
                     YARYPHIKQVGLCHSVQGTAEELARDLNIDPATLRYRCAGINHMAFYLELERKTADGS
                     YVNLYPELLAAYEAGQAPKPNIHGNTRCQNIVRYEMFKKLGYFVTESSEHFAEYTPWF
                     IKPGREDLIERYKVPLDEYPKRCVEQLANWHKELEEYKKASRIDIKPSREYASTIMNA
                     IWTGEPSVIYGNVRNDGLIDNLPQGCCVEVACLVDANGIQPTKVGTLPSHLAALMQTN
                     INVQTLLTEAILTENRDRVYHAAMMDPHTAAVLGIDEIYALVDDLIAAHGDWLPGWLH
                     R"
     gene            16346..17767
                     /gene="melB"
                     /locus_tag="RN951_001853"
     CDS             16346..17767
                     /gene="melB"
                     /locus_tag="RN951_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418544.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="melibiose:sodium transporter MelB"
                     /protein_id="HDX2526861.1"
                     /translation="MSISMTTKLSYGFGAFGKDFAIGIVYMYLMYYYTDVVGLSVGLV
                     GTLFLVARIWDAINDPIMGWIVNATRSRWGKFKPWILIGTLANSVILFLLFSAHLFEG
                     TTQIVFVCVTYILWGMTYTIMDIPFWSLVPTITLDKREREQLVPYPRFFASLAGFVTA
                     GVTLPFVNYVGGGDRGFGFQMFTLVLIAFFIVSTIITLRNVHEVFSSDNQPSAEGSHL
                     TLKAIVALIYKNDQLSCLLGMALAYNVASNIITGFAIYYFSYVIGDADLFPYYLSYAG
                     AANLVTLVFFPRLVKSLSRRILWAGASILPVLSCGVLLLMALMSYHNVVLIVIAGILL
                     NVGTALFWVLQVIMVADIVDYGEYKLHVRCESIAYSVQTIVVKGGSAFAAFFIAVVLG
                     MIGYVPNVEQSTQALLGMQFIMIALPTLFFMVTLILYFRFYRLNGDTLRRIQIHLLDK
                     YRKVPPEPVHADIPVGAVSDVKA"
     gene            complement(17906..18535)
                     /locus_tag="RN951_001854"
     CDS             complement(17906..18535)
                     /locus_tag="RN951_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2238 domain-containing protein"
                     /protein_id="HDX2526862.1"
                     /translation="MTRTLKPLILNTSALTLTLILIYTGISAHDKLTWLMEVTPVIIV
                     VQLLLATARRYPLTPLLYTLIFLHAIILMVGGQYTYAKVPVGFEVQEWLGLSRNPYDK
                     LGHFFQGLVPALVAREILVRGMYVRGRKMVAFLVCCVALAISAMYELIEWWAALAMGQ
                     GADDFLGTQGDQWDTQSDMFCALLGALTTVIFLARFHCRQLRRFGLITG"
     gene            complement(18658..20304)
                     /gene="fumB"
                     /locus_tag="RN951_001855"
     CDS             complement(18658..20304)
                     /gene="fumB"
                     /locus_tag="RN951_001855"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fumarate hydratase"
                     /protein_id="HDX2526863.1"
                     /translation="MSNKPFIYQAPFPMGKDNTEYYLLTSDYVSVADFDGETILKVEP
                     EALTLLAQQAFHDASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVL
                     PTCQDTGTAIIVGKKGQRVWTGGGDEETLSKGVYNTYIEDNLRYSQNAALDMYKEVNT
                     GTNLPAQIDLYAVDGDEYKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRT
                     LGTAACPPYHIAFVIGGTSAETNLKTVKLASAHYYDELPTEGNEHGQAFRDVQLEQEL
                     LEEAQKLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIW
                     IEKLEHNPGQYIPQELRQAGEGEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVG
                     RDIAHAKLKELIDAGKELPQYIKDHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDL
                     LQSHGGSMIMLAKGNRSQQVTDACHKHGGFYLGSIGGPAAVLAQQSIKHLECVAYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIVNKQCANCTK"
     gene            complement(20382..21722)
                     /gene="dcuB"
                     /locus_tag="RN951_001856"
     CDS             complement(20382..21722)
                     /gene="dcuB"
                     /locus_tag="RN951_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuB"
                     /protein_id="HDX2526864.1"
                     /translation="MLFTIQLIIILICLFYGARKGGIALGLLGGIGLVILVFVFHLQP
                     GKPPVDVMLVIIAVVAASATLQASGGLDVMLQIAEKLLRRNPKYVSIVAPFVTCTLTI
                     LCGTGHVVYTILPIIYDVAIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLG
                     NVTFDGRHLEFLDLLAITIPSTLIGILAIGIFSWFRGKDLDKDEEFQKFISVPENREY
                     VYGDTATLLDKKLPKSNWLAMWIFLGAIAVVALLGADSDLRPSFGGKPLSMVLVIQMF
                     MLLTGALIIILTKTNPASISKNEVFRSGMIAIVAVYGIAWMAETMFGAHMSEIQGVLG
                     EMVKEYPWAYAIVLLLVSKFVNSQAAALAAIVPVALAIGVDPAYIVASAPACYGYYIL
                     PTYPSDLAAIQFDRSGTTHIGRFVINHSFILPGLIGVSVSCVFGWIFAAMYGFL"
     gene            complement(22293..23012)
                     /gene="dcuR"
                     /locus_tag="RN951_001857"
     CDS             complement(22293..23012)
                     /gene="dcuR"
                     /locus_tag="RN951_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator DcuR"
                     /protein_id="HDX2526865.1"
                     /translation="MINVLIIDDDAMVAELNRRYVAQIPGFQCCGTASTLEKAKEIIF
                     NSDTPIDLILLDIYMQKENGLDLLPVLHNARCKSDVIVISSAADAATIKDSLHYGVVD
                     YLIKPFQASRFEEALTGWRQKKMALEKHQYYDQAELDQLIHGSSSNEQDPRRLPKGLT
                     PQTLRTLCQWIDAHQDYEFSTDELANEVNISRVSCRKYLIWLVNCHILFTSIHYGVTG
                     RPVYRYRIQAEHYSLLKQYCQ"
     gene            complement(23009..24640)
                     /gene="dcuS"
                     /locus_tag="RN951_001858"
     CDS             complement(23009..24640)
                     /gene="dcuS"
                     /locus_tag="RN951_001858"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     DcuS"
                     /protein_id="HDX2526866.1"
                     /translation="MRHSLPYRMLRKRPMKLSTTVILMVSAVLFSVLLVVHLIYFSQI
                     SDMTRDGLANKALAVARTLADSPEIRQGLQKKPQESGIQAIAEAVRKRNDLLFIVVTD
                     MQSLRYSHPEAQRIGQPFKGDDILKALNGEENVAINRGFLAQALRVFTPIYDENHKQI
                     GVVAIGLELSRVTQQINDSRWSIIWSVLFGMLVGLIGTCILVKVLKKILFGLEPYEIS
                     TLFEQRQAMLQSIKEGVVAVDDRGEVTLINDAAQELLNYRKSQDDEKLSTLSHSWSQV
                     VDVSEVLRDGTPRRDEEITIKDRLLLINTVPVRSNGVIIGAISTFRDKTEVRKLMQRL
                     DGLVNYADALRERSHEFMNKLHVILGLLHLKSYKQLEDYILKTANNYQEEIGSLLGKI
                     KSPVIAGFLISKINRATDLGHTLILNSESQLPDSGSEDQVATLITTLGNLIENALEAL
                     GPEPGGEISVTLHYRHGWLHCEVNDDGPGIAPDKIDHIFDKGVSTKGSERGVGLALVK
                     QQVENLGGSIAVESEPGIFTQFFVQIPWDGERSNR"
     gene            24821..25051
                     /locus_tag="RN951_001859"
     CDS             24821..25051
                     /locus_tag="RN951_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HDX2526867.1"
                     /translation="MDQALLDGGYRCYTGEKIDVYFNTAICQHSGNCVRGNGKLFNLK
                     RKPWIMPDEVDVATVVKVIDTCPSGALKYRHK"
     gene            25063..25335
                     /locus_tag="RN951_001860"
     CDS             25063..25335
                     /locus_tag="RN951_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDX2526868.1"
                     /translation="MEIREGHNKFYINDKQGKQIAEIVFVPTGENLAIIEHTDVDESL
                     KGQGIGKQLVAKVVEKMRREKRKIIPLCPFAKHEFDKTREYDDIRS"
     gene            25562..25858
                     /gene="ghoS"
                     /locus_tag="RN951_001861"
     CDS             25562..25858
                     /gene="ghoS"
                     /locus_tag="RN951_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system endoribonuclease
                     antitoxin GhoS"
                     /protein_id="HDX2526869.1"
                     /translation="MEGKNKFNTYVVSFDYPSSYSSVFLRLRSLMYDMNFSSIVADEY
                     GIPRQLNENSFAITTSLAASEIEDLIRLKCLDLPDIDFDLNIMTVDDYFRQFYK"
     gene            25886..26059
                     /gene="ghoT"
                     /locus_tag="RN951_001862"
     CDS             25886..26059
                     /gene="ghoT"
                     /locus_tag="RN951_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system toxin GhoT"
                     /protein_id="HDX2526870.1"
                     /translation="MALFSKILIFYVIGVNISFVIIWFISHEKTHIRLLSAFLVGITW
                     PMSLPVALLFSLF"
     gene            complement(26178..27695)
                     /gene="lysS"
                     /locus_tag="RN951_001863"
     CDS             complement(26178..27695)
                     /gene="lysS"
                     /locus_tag="RN951_001863"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDX2526871.1"
                     /translation="MSEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDH
                     TSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD
                     SLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGL
                     QDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGA
                     SARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFT
                     MMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIK
                     KYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITE
                     YPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAG
                     DDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMRPQK"
     gene            complement(27932..29389)
                     /gene="dtpC"
                     /locus_tag="RN951_001864"
     CDS             complement(27932..29389)
                     /gene="dtpC"
                     /locus_tag="RN951_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpC"
                     /protein_id="HDX2526872.1"
                     /translation="MKTPSQPRAIYYIVAIQIWEYFSFYGMRALLILYLTHQLGFDDN
                     HAISLFSAYASLVYVTPILGGWLADRLLGNRTAVIAGALLMTLGHVVLGIDTNSTFSL
                     YLALAIIICGYGLFKSNISCLLGELYDENDHRRDGGFSLLYAAGNIGSIAAPIACGLA
                     AQWYGWHVGFALAGGGMFIGLLIFLSGHRHFQSTRSMDKKALTSVKFALPVWSWLVVM
                     LCLAPVFFTLLLENDWSGYLLAIVCLIAAQIIARMMIKFPEHRRALWQIVLLMFVGTL
                     FWVLAQQGGSTISLFIDRFVNRQAFNIEVPTALFQSVNAIAVMLAGVVLAWLASPESR
                     GNSTLRVWLKFAFGLLLMACGFMLLAFDARHAAADGQASMGVMISGLALMGFAELFID
                     PVAIAQITRLKMSGVLTGIYMLATGAVANWLAGVVAQQTTESQISGMAIAAYQRFFSQ
                     MGEWTLACVAIIVVLAFATRFLFSTPTNMIQESND"
     gene            complement(29448..31595)
                     /gene="cadA"
                     /locus_tag="RN951_001865"
     CDS             complement(29448..31595)
                     /gene="cadA"
                     /locus_tag="RN951_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase CadA"
                     /protein_id="HDX2526873.1"
                     /translation="MNVIAILNHMGVYFKEEPIRELHRALERLNFQIVYPNDRDDLLK
                     LIENNARLCGVIFDWDKYNLELCEEISKMNENLPLYAFANTYSTLDVSLNDLRLQISF
                     FEYALGAAEDIANKIKQTTDEYINTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQK
                     SPVGSLFYDFFGPNTMKSDISISVSELGSLLDHSGPHKEAEQYIARVFNADRSYMVTN
                     GTSTANKIVGMYSAPAGSTILIDRNCHKSLTHLMMMSDVTPIYFRPTRNAYGILGGIP
                     QSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKKTLDVKSIHFDSAWV
                     PYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHKLLAAFSQASMIHVKGDVNEETFNEA
                     YMMHTTTSPHYGIVASTETAAAMMKGNAGKRLINGSIERAIKFRKEIKRLRTESDGWF
                     FDVWQPDHIDTTECWPLRSDSTWHGFKNIDNEHMYLDPIKVTLLTPGMEKDGTMSDFG
                     IPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAFDLNLRV
                     KNMLPSLYREDPEFYENMRIQELAQNIHKLIVHHNLPDLMYRAFEVLPTMVMTPYAAF
                     QKELHGMTEEVYLDEMVGRINANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEI
                     GAHYPGFETDIHGAYRQADGRYTVKVLKEESKK"
     gene            complement(31675..33009)
                     /gene="cadB"
                     /locus_tag="RN951_001866"
     CDS             complement(31675..33009)
                     /gene="cadB"
                     /locus_tag="RN951_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadaverine/lysine antiporter"
                     /protein_id="HDX2526874.1"
                     /translation="MSSAKKIGLFACTGVVAGNMMGSGIALLPANLASIGGIAIWGWI
                     ISIIGAMSLAYVYARLATKNPQQGGPIAYAGEISPAFGFQTGVLYYHANWIGNLAIGI
                     TAVSYLSTFFPVLNDPVPAGIACIAIVWVFTFVNMLGGTWVSRLTTIGLVLVLIPVVM
                     TAIVGWHWFDAATYAANWNTADTTDGHAIIKSILLCLWAFVGVESAAVSTGMVKNPKR
                     TVPLATMLGTGLAGIVYIAATQVLSGMYPSSVMAASGAPFAISASTILGNWAAPLVSA
                     FTAFACLTSLGSWMMLVGQAGVRAANDGNFPKVYGEVDSNGIPKKGLLLAAVKMTALM
                     ILITLMNSAGGKASDLFGELTGIAVLLTMLPYFYSCVDLIRFEGVNIRNFVSLICSVL
                     GCVFCFIALMGASSFELAGTFIVSLIILMFYARKMHERQSHSMDNHTASNAH"
     gene            complement(33374..34912)
                     /gene="cadC"
                     /locus_tag="RN951_001867"
     CDS             complement(33374..34912)
                     /gene="cadC"
                     /locus_tag="RN951_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylation/transport transcriptional
                     activator CadC"
                     /protein_id="HDX2526875.1"
                     /translation="MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHS
                     GEVLSRDELIDNVWKRSIVTNHVVTQSISELRKSLKDNDEDSPVYIATVPKRGYKLMV
                     PVIWYSEEEGEEIMLSSPPPIPEAVPATDSPSHSLNIQNTATPPEQSPVKSKRFTTFW
                     VWFFFLLSLGICVALVAFSSLDTRLPMSKSRILLNPRDIDINMVNKSCNSWSSPYQLS
                     YAIGVGDLVATSLNTFSTFMVHDKINYNIDEPSSSGKTLSIAFVNQRQYRAQQCFMSI
                     KLVDNADGSTMLDKRYVITNGNQLAIQNDLLESLSKALNQPWPQRMQETLQKILPHRG
                     ALLTNFYQAHDYLLHGDDKSLNRASELLGEIVQSSPEFTYARAEKALVDIVRHSQHPL
                     DEKQLAALNTEIDNIVTLPELNNLSIIYQIKAVSALVKGKTDESYQAINTGIDLEMSW
                     LNYVLLGKVYEMKGMNREAADAYLTAFNLRPGANTLYWIENGIFQTSVPYVVPYLDKF
                     LASE"
     gene            complement(35529..35604)
                     /locus_tag="RN951_001868"
     tRNA            complement(35529..35604)
                     /locus_tag="RN951_001868"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(35569..35571),aa:Phe,seq:gaa)
     gene            complement(35711..36286)
                     /locus_tag="RN951_001869"
     CDS             complement(35711..36286)
                     /locus_tag="RN951_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDX2526876.1"
                     /translation="MQREDVLGEALKLLELQGIANTTLEMVAERVDYPLDELRRFWPD
                     KEAILYDALRYLSQQIDVWRRQLMLDETQTAEQKLLARYQALSECVKNNRYPGCLFIA
                     ACTFYPDPGHPIHQLADQQKSAAYDFTHELLTTLEVDDPAMVAKQMELVLEGCLSRML
                     VNRSQADVDTAHRLAEDILRFARCRQGGALT"
     gene            complement(36323..38020)
                     /gene="dsbD"
                     /locus_tag="RN951_001870"
     CDS             complement(36323..38020)
                     /gene="dsbD"
                     /locus_tag="RN951_001870"
                     /EC_number="1.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD"
                     /protein_id="HDX2526877.1"
                     /translation="MAQRIFTLILLLCSTSVFAGLFDAPGRSQFVPADQAFAFDFQQN
                     QHDLNLTWQIKDGYYLYRKQIRITPEHAKIADVQLPQGVWHEDEFYGKSEIYRDRLTL
                     PVTINQASAGATLTVTYQGCADAGFCYPPETKTVPLSEVVANNAAPQPVSVPQQEQPT
                     AQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARALLLTFIYVQGMA
                     LTYTALGLVVAAAGLQFQAALQHPYVLIGLAIVFTLLAMSMFGLFTLQLPSSLQTRLT
                     LMSNRQQGGSPGGVFVMGAIAGLICSPCTTAPLSAILLYIAQSGNMWLGGGTLYLYAL
                     GMGLPLMLITVFGNRLLPKSGPWMEQVKTAFGFVILALPVFLLERVIGDVWGLRLWSA
                     LGVAFFGWAFITSLQAKRGWMRIVQIILLAAALVSVRPLQDWAFGATHTAQTQTHLNF
                     TQIKTVDELNQALVEAKGKPVMLDLYADWCVACKEFEKYTFSDPQVQKALADTVLLQA
                     NVTANDAQDVALLKHLNVLGLPTILFFDGQGQEHPQARVTGFMDAETFSAHLRDRQP"
     gene            complement(37996..38334)
                     /gene="cutA"
                     /locus_tag="RN951_001871"
     CDS             complement(37996..38334)
                     /gene="cutA"
                     /locus_tag="RN951_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent cation tolerance protein CutA"
                     /protein_id="HDX2526878.1"
                     /translation="MLDEKSSNTASVVVLCTAPDEATAQDLAAKVLAEKLAACATLIP
                     GATSLYYWEGKLEQEYEVQMILKTTVSHQQALLECLKSHHPYQTPELLVLPVTHGDTD
                     YLSWLNASLR"
     gene            complement(38450..39751)
                     /gene="dcuA"
                     /locus_tag="RN951_001872"
     CDS             complement(38450..39751)
                     /gene="dcuA"
                     /locus_tag="RN951_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuA"
                     /protein_id="HDX2526879.1"
                     /translation="MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGN
                     IPFDVISIIMAVIAAISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFA
                     GTGNISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGH
                     GISYLHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIE
                     IKSGAKTSVWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVI
                     CKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLA
                     VIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQ
                     MDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLGSFML"
     gene            complement(39869..41305)
                     /gene="aspA"
                     /locus_tag="RN951_001873"
     CDS             complement(39869..41305)
                     /gene="aspA"
                     /locus_tag="RN951_001873"
                     /EC_number="4.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313147.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate ammonia-lyase"
                     /protein_id="HDX2526880.1"
                     /translation="MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDI
                     PEFVRGMVMVKKAAAMANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGA
                     GTSVNMNTNEVLANIGLELMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSL
                     IKLVDAINQLREGFERKAVEFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKNI
                     QRTAELLLEVNLGATAIGTGLNTPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGA
                     YVMVHGALKRLAVKMSKICNDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPE
                     VVNQVCFKVIGNDTTVTMAAEAGQLQLNVMEPVIGQAMFESVHILTNACYNLLEKCIN
                     GITANKEVCEGYVYNSIGIVTYLNPFIGHHNGDIVGKICAETGKSVREVVLERGLLTE
                     AELDDIFSVQNLMHPAYKAKRYTDESEQ"
     gene            41642..42118
                     /gene="fxsA"
                     /locus_tag="RN951_001874"
     CDS             41642..42118
                     /gene="fxsA"
                     /locus_tag="RN951_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418564.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein FxsA"
                     /protein_id="HDX2526881.1"
                     /translation="MRWLPFIAIFLYVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGM
                     SLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLIIAGLLLLLPGFFTDFLGLLLLLP
                     PVQKHLTVKLMPHLRFSRMPGGGFSAGTGGGNTFDGEYQRKDDERDRLDHKDDRQD"
     gene            complement(42134..43390)
                     /gene="yjeH"
                     /locus_tag="RN951_001875"
     CDS             complement(42134..43390)
                     /gene="yjeH"
                     /locus_tag="RN951_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine/branched-chain amino acid
                     transporter"
                     /protein_id="HDX2526882.1"
                     /translation="MSGLKQELGLAQGIGLLSTSLLGTGVFAVPALAALVAGNNSLWA
                     WPVLIILVFPIAIVFAILGRHYPSAGGVAHFVGMAFGSRLERVTGWLFLSVIPVGLPA
                     ALQIAAGFGQAMFGWHSWQLLLAELGTLALVWYIGTRGASSSANLQTVIAGLIVALIV
                     AIWWAGDIKPANIPFPAPGNIELTGLFAALSVMFWCFVGLEAFAHLASEFKNPERDFP
                     RALMIGLLLAGLVYWGCTVVVLHFDAYGEKMAAAASLPKIVVQLFGVGALWIACVIGY
                     LACFASLNIYIQSFARLVWSQAQHNPDHYLARLSSRHIPNNALNAVLGCCVVSTLVIH
                     ALEINLDALIIYANGIFIMIYLLCMLAGCKLLQGRYRLLAVVGGLLCVLLLAMVGWKS
                     LYALIMLAGLWLLLPKRKTPENGITT"
     gene            43666..43959
                     /locus_tag="RN951_001876"
     CDS             43666..43959
                     /locus_tag="RN951_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000027827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HDX2526883.1"
                     /translation="MNIRPLHDRVIVKRKEVETKSAGGIVLTGSAAAKSTRGEVLAVG
                     NGRILENGEVKPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA"
     gene            44003..45649
                     /gene="groL"
                     /locus_tag="RN951_001877"
     CDS             44003..45649
                     /gene="groL"
                     /locus_tag="RN951_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120975.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HDX2526884.1"
                     /translation="MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSF
                     GAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITE
                     GLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGK
                     LIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESP
                     FILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAV
                     KAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIID
                     GVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEK
                     KARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAP
                     LRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAA
                     SVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM"
     gene            45787..46140
                     /locus_tag="RN951_001878"
     CDS             45787..46140
                     /locus_tag="RN951_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4156 domain-containing protein"
                     /protein_id="HDX2526885.1"
                     /translation="MHVKYLAGIVGAALLMAGCSSSNELSAAGQSVRIVDEQPGAECQ
                     LIGTATGKQSNWLSGQHGEEGGSMRGAANDLRNQAAAMGGNVIYGISSPSQGMLSSFV
                     PADSQIIGQVYKCPN"
     gene            complement(46343..47212)
                     /locus_tag="RN951_001879"
     CDS             complement(46343..47212)
                     /locus_tag="RN951_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjeJ family protein"
                     /protein_id="HDX2526886.1"
                     /translation="MAISIKGVNTGVIRKSNNFIALALKIKEPRNKESLFFMSVMELR
                     DLLIALESRLHQKHKLDAAAHLQYEQARDKVIKKMAENIPEILVDELKNADINRRVNT
                     LELTDNQGENLTFVLTLHDGSKCELVVNELQIEMLARAIIHAINNAEMRELALRITSL
                     LDFLPLYDVDCQDNGNLEYDTYSQPEWKHNLFDHYLAVLYRFKDESGKEQFSGAVVKT
                     REATPGKEIEAITRRMLDFSPRLKKLAGVPCQVYVRTVAANNAQPLTQDQCLRALHHL
                     RVQSTSKTAPQAK"
BASE COUNT        12004 a        11369 c        11923 g        11968 t
ORIGIN      
        1 acacactaaa tataaaatta tttcttgcag taattataaa agccgaaaac agaactcaaa
       61 aacaatctgg ctaaataaaa taacaaaatt tgctttaagg aagaattttc tatgtacaca
      121 cagaccctgt atgagttaag tcaggaggct gaacgcctgt tacagctttc tcgccaacag
      181 ttgcagttac tggaaaaaat gcctctctct gtacccggag acgacgcgcc acaactggct
      241 ttaccctgga gtcagcctaa tatcgccgaa cgtcacgcga tgctgaataa tgagttgcgt
      301 aaaatttccc gactggaaat ggtgcttgca attgtcggta ccatgaaagc agggaaatca
      361 accaccatta atgccattgt tggtacggag gttctgccta atcgtaatcg cccaatgact
      421 gcgctgccga cgcttattcg ccatacgccc gggcaaaagg aaccggtact gcatttttca
      481 catgtcgcgc caatcgattg tttaattcaa caattacaac agcgcctgcg tgattgcgat
      541 attaagcatc tgaccgatgt gctggaaata gataaagata tgcgtgcgct tatgcagcgg
      601 atcgaaaatg gcgtcgcttt cgaaaaatat tatctgggtg cccagcctat ttttcattgt
      661 ctgaaaagtt tgaatgattt agtgcgactg gcgaaggcgc tggacgtcga ttttcctttt
      721 tctgcttacg ccgccattga gcatattccc gtgattgaag tggagtttgt ccatctagcg
      781 gggctggaga gttatcccgg tcagttgacg ttactggata cccccgggcc aaatgaagcc
      841 gggcaaccgc atctgcaaaa aatgcttaac cagcagctgg cacgcgcctc ggcggtactg
      901 gcggtgctgg attatacgca actgaaatcg atctccgatg aagaggtccg tgaggcgatt
      961 ttggcggtgg ggcaatcggt gccgctgtac gtgctggtca ataagttcga tcaacaggat
     1021 cgtaacagtg acgacgccga ccaggtgcgg gcactgattt ccgggacgct gatgaaaggc
     1081 tgtattacgc cacagcagat atttccggtg tcgtcgatgt ggggctacct ggcgaatcgg
     1141 gcgcgctatg agttagccaa caacggtaag ttaccaccgc cagagcaaca acgctgggtg
     1201 gaagattttg cccatgccgc gcttggcagg cgctggcgtc atgccgatct ggcggacctc
     1261 gaacatattc gtcatgctgc cgatcagttg tgggaagatt cgctgttcgc ccagccaatt
     1321 caggcgttgc ttcatgccgc ttacgctaac gcctcgttgt atgctctgcg atctgccgcg
     1381 cataaactgt tgaattacgc gcagcaggcg cgggaatacc tggattttcg tgcgcacggg
     1441 ttaaacgtcg cttgtgaaca attgcggcaa aatatccacc agatcgaaga aagtttgcag
     1501 ctattgcaac tcaatcaggc gcaggtgagc ggcgagatta aacatgaaat cgagctggcc
     1561 ctgacctccg ccaaccactt tctgcgtcaa cagcaagatg cgctgaaggt gcagttagcc
     1621 gccttgtttc aggatgattc ggagccgtta agcgagattc gtacccgctg tgagacactg
     1681 ttacagacgg cgcagaacac catcagtcgc gactttacgc tgcgttttgc cgagcttgaa
     1741 tccacccttt gccgggtgtt aaccgatgtt attcgcccca ttgagcaaca agtcaaaatg
     1801 gaattgagcg agtcagggtt tcgtcctggg tttcattttc ctgtttttca cggcgtagtt
     1861 ccccacttca acactcgcca gctgttcagt gaagtcattt cgcgccagga agcaacggac
     1921 gagcagagca cgcgtttagg cgttgtgcgt gagacttttt cgcgctggtt gaatcagccc
     1981 gactggggac ggggaaatga gaaatcaccg acagaaacgg ttgattacag tgtgttgcaa
     2041 cgagcattaa gcgcagaagt cgatctctat tgccaacaaa tggctaaagt tctggcagag
     2101 caggtcgatg aatctgttac ggcaggcatg aatacttttt tcgctgagtt cgcttcatgt
     2161 ttgacggaat tacagacgcg tttacgcgaa agtctggctc tgcgtcaaca aaatgaatcg
     2221 gtggtcaggc tgatgcagca gcaattgcag cagactgtga tgactcacgg ctggatttac
     2281 accgacgccc agctgttacg cgatgatatt caaacacttt tcacggcaga acgatattga
     2341 ccaagacgtt acttgacggc cccggtcgcg tgctggagtc ggtttatccc cgctttttag
     2401 tggatctggc gcagggtgat gatgcccgcc ttccacaagc ccatcagcag cagtttcgtg
     2461 aacgactgat gcaggaactt ctttcgcgtg tgcagcttca gacatggacg aacggcggca
     2521 tgttaaatgc gccgcttagc ctgcgtctga cattggtgga aaaactggcg tcgatgctgg
     2581 atcccggtca tctggcactg acgcagatcg cgcagcatct ggcgctgctg caaaaaatgg
     2641 atcaccgcca gcactctgct ttcccggagc tcccccagca aattgccgcc ttgtatgagt
     2701 ggttttcagc ccgttgtcgc tggaaggaaa aggcgttaac gcaacgaggc ctactggtgc
     2761 aggcaggtga tcagagcgag caaattttta cccgctggcg tgctggggcg tataacgcct
     2821 ggtcgttgcc tgggcgctgt tttatcgttc tggaggagtt gcgctggggg gcatttggcg
     2881 atgcctgccg tctgggaagc ccgcaagcgg tggcgttgtt gctgggtgat ttgctcgaga
     2941 aagcgacaca acatctggca gagagtatca atgcggcacc gaccacgcgt cactattacc
     3001 atcagtggtt tgcctcttcg accgttccga cgggcgggga gcatgctgat tttttaagtt
     3061 ggctgggaaa gtggaccacg gcagataaac aacccgtttg ctggtcagtg acccaacgct
     3121 ggcaaactgt cgcgctgggg atgccacgac tctgttcagc gcagcgtctg gcgggggcaa
     3181 tgctcgagga aatcttctct gtaaatttgg cgtaaataat cagttacatc aatgagtcct
     3241 aaacgaaatc catgtgtgaa gttgatcaca aatttaaaca ctggtagggt aaaaaggtca
     3301 ttaactgccc aattcaggcg tcaactggtt tgattgtaca ttccttaacc ggagggtgta
     3361 agcaaacccg ctacgcttgt tacagagatt gcatcctgca attcccgctc cccttttgcg
     3421 gccgtcgcgc tgatttttct ggcgtttgcg gaaatgggcc aactctgcga ggaaagctat
     3481 gctgaaaagg aaaaaagtaa aaccgattac ccttcgtgat gtcaccatta ttgatgacgg
     3541 taaactgcgt aaagccatta ccgcagcatc actgggtaat gcaatggaat ggttcgattt
     3601 tggtgtttat ggttttgttg cttacgcatt aggtaaagtt tttttcccgg gggctgaccc
     3661 cagcgtgcag atggttgctg cacttgccac tttctccgtt ccctttctga ttcgaccgct
     3721 tggcggactc ttctttggta tgttgggcga taaatatggt cgccagaaga tcctcgctat
     3781 cactattgtg attatgtcga tcagtacgtt ctgtattggc ttaataccgt cctacgacac
     3841 gattggtatt tgggcaccga ttctgctgtt gatctgtaag atggcacaag gtttctcggt
     3901 cggcggtgaa tataccgggg cgtcgatatt tgttgcggaa tactcccctg accgtaaacg
     3961 tggctttatg ggcagctggc tggacttcgg ttctattgcc gggtttgtgc tgggtgcggg
     4021 cgtggtggtg ttaatttcga ccattgtcgg cgaagcgaac ttcctcgatt ggggctggcg
     4081 tattccgttc tttatcgctc tgccgttagg gattatcggg ctttacctgc gccatgcgct
     4141 ggaagagact ccggcgttcc agcagcatgt cgataaactg gaacagggcg accgtgaagg
     4201 tttgcaggat ggcccgaaag tctcgtttaa agagattgcc actaaatact ggcgcagcct
     4261 gttgacatgt attggtctgg taattgccac caacgtgact tactacatgt tgctgaccta
     4321 tatgccgagt tatttgtcgc ataacctgca ttactccgaa gaccacgggg tgctgattat
     4381 tatcgccatt atgatcggta tgctgtttgt ccagccggtg atgggcttgc tgagtgaccg
     4441 ttttggccgt cgtccgtttg tgctacttgg tagtgttgcc ctgtttgtgt tggcgatccc
     4501 ggcgtttatt ctgattaaca gtaacgtcat cggcctgatt tttgccgggt tactgatgct
     4561 ggcggtgatc cttaactgct ttacgggcgt tatggcttct accttgccag cgatgttccc
     4621 gacgcatatc cgttacagcg cgctggcggc ggcatttaat atttcggtgc tggttgccgg
     4681 tctgacgcca acgctggcgg cctggctggt cgaaagctcg cagaatctga tgatgcctgc
     4741 ctattacctg atggtagtgg cggtggttgg tttaatcacc ggcgtaacca tgaaagagac
     4801 ggcaaatcgt ccgttgaaag gtgcgacacc ggcggcgtca gatatacagg aagcgaagga
     4861 aattctcgtc gagcattacg ataatatcga gcagaaaatc gatgatattg accacgagat
     4921 tgccgatttg caggcgaaac gtacccgcct ggtgcagcaa catccgcgaa ttgatgaata
     4981 agctgaaacg gatggcctga tgtgacgctg tcttatcagg ccaattgaac tcttaaggtt
     5041 cacttaatct ctgacgcgca tactctcctc caggttaacg gaggagagtg caatgaaaaa
     5101 ccgtgtttat gaaagtttaa ctaccgtgtt cagcgtgctg gtggtcagca gctttcttta
     5161 tatctggttt gccacgtact gatctttctt cagccgtacc caggcccgcg tgccggaagt
     5221 ctcttgccgg ttttgcagga aaaactgccc gtgatgcaac tgtgtaatgc ggctgacaat
     5281 acttaacccc agaccaatcc cgccataacg gctgtccata cgtacaaacg ctttactcaa
     5341 ctccccgcat ttactctcat caatacctgg tccttcatct tcaactgcca tgaccgctcc
     5401 gtcatcttct tgcagcttaa tcataatgtt gctgccttgc gggctgtaac gatgggcgtt
     5461 ttctaccagg tttcgcaata acatccgcag cagggttgca tcaccctgaa cggtgatgtc
     5521 ggcggcgctc tctggcaata gcagggtttg ctgtcgctgg tcgagcatgg tactgagttc
     5581 gtcatacgag gggagaatga catcttccag cagttttaca tgttgataat taccggaaga
     5641 aaatgactgt ccggcacgcg ccagttgcag cagctgggag acgctctcca tcatctgatc
     5701 aagccgtgcc actaacggtg ctacatcaat gtgatgcgtt ttcgccagca gttccagatg
     5761 caaacgcacc cccgccagtg gcgttcgcag ttcgtgcgcg acgtcagcgg taaacaacct
     5821 ttcgttatcc agcgtgctgg tcaggcgact gaccagatcg tttaacgccg aaaccaccgc
     5881 ttcgatttcg agggtggcgc tgtgaatggc aatgggcgtt aagttgtcgg cggtgcgcgc
     5941 ttccagctct ttttgcagct ccgccagcgg gcgggtgatg cggcgtaccg cctgatagca
     6001 gataaatagc gtcaggctga ccataaagac gccggggaca atcaggctgg cgaccgcctc
     6061 gcggatctca cgcatgatgt ggcgatcgtt gttgcgattg tcgcgtagcg cctgctcaaa
     6121 cagctgaatc tgctcggtac tttcatgcca tagccagaag acgctgatca gctcaaacac
     6181 caacaaaatg gccccgatgg tcaatatcag ccgttggcgc agcgatattg gtcggcgcag
     6241 aaaatgcatc agattcaatt agttttcctc attcgcgacc agcatatagc caaagccgcg
     6301 cacggtgcgg atacgggctt tgcccacttt gtcgcgcaga ttgtggatat gcacttccag
     6361 ggtgttggtc gagggttcat tgtcccagtt atagatgtcg ttgtagagaa tttcccgatg
     6421 caccggactg cctgctttga gcattaaccg tgacagcaga gcatattctt tgggcgtcag
     6481 aatcaactct tcaccgccca tccatacctg acggcgaccc atgttcagcg tcagattgcc
     6541 aacaatcagc tcactttcgc cctgattatt atggcgtcgt agcagggcgc ggatacgggc
     6601 atgtaactct tccagcgcaa aaggcttcac cagatagtcg tcggcaccga catccagccc
     6661 ggcgattttg tcggtcagcg tatcgcgagc ggtgaggatc agtaccggca gggtatattt
     6721 tttctgccgg atacgggtga gaaaatgcag tccatcttcg tcgggtaacc ctaaatccag
     6781 taccaccagg ctgtaatgac ctgcctcaag gctttgttcc gccatccgcg cggttgtcac
     6841 gccatcgcac gcgtagcctt cggtttgcgc cgccagaatc agtccctgca ataacagcgt
     6901 atcgtcttca acaatcagaa ttttcattca ctcactctcc tgcaagtttg cagaatatca
     6961 tccgcagcct ggtaatactt cgtctcaacg ccagttaatc ccaatagcgt ggagaataaa
     7021 ttgtcttgtg aatagtgttg cgtttgcgcc tgtttttgca ggcagttctg gtcaacctga
     7081 taccgttttt gataatcctc cgacagccac agcagcatcg gcacctgttt ttggctatcc
     7141 ggggcgatgg cataaggcag accgtgcaga tagatgccat tttcacctaa cgattcaccg
     7201 tggtcagaaa gataaaccag gctggtggta aatttatcct gatgttcttt cagcagatta
     7261 atcgctttat caacaatata gtcgacgtaa accagcgtgt tgtcgtaagt gttcaccagt
     7321 tgctctttgg tacaggtctg gatctcattg gtgtcgcagg ttggggtaaa tttcctgaac
     7381 tgaggcggat agcggttgta ataggtcgga ccgtggctgc cgatggtgtg taagacaatc
     7441 acgccatcac cttgcaggtt attgatgtac tcttcaagcc cgtggaacag cacttcgtca
     7501 tagcattcgc cgttgatgca ctgatcaggt agattcagcg cggtgacgtt ctggtgaggc
     7561 acgcggtcgc aggcaccttt acagccgcca tcgttgtcat tccacagcac gttgatgccc
     7621 gctcgctgaa tgatatccag cacgccttcc tggtgctgtg ccagctcttc tttgtagtgc
     7681 tcacgcggca tatccgagaa catgcacggt actgaaactg ccgttgccgt gccgcaagat
     7741 gcggtattag ggaaatagac cacgttatct ttcgccagcc gcgggttagt ttcacgcggg
     7801 tagccgttga gggagaagtt ctccgcccgc gaggtttcgc cgacaatcag gatggtcaaa
     7861 tttttacgtt tttcgttctg cattaacggg ttgcggtgcg cgtcttcacc aattcgcacc
     7921 agcggcagat ttgccagtcg ctgatgggag taccatgacc agctggcaac aatgctgtta
     7981 gaggggctta aggatttcac cagctctttg ttattgcgga acaacgaggc gtagtcttta
     8041 taaaacagtg cggcgaccag caaaatcagt agtacagaaa ccagaatatt ggctccacgg
     8101 aaaagaacac tgcgcagacg cgaggtggca ggtttgattt ttatccagca ggcaatcagc
     8161 gcagcaagca cgccgctgaa tcccagcgtt aataacattt gcggtgtcat cagcgcataa
     8221 ctttctgccg gagtggtatc aataatattg gcaatcatcg agcggtcgat gacgatgccg
     8281 taagtcatta tgaaatattg tgcagccgcg ccaaccagaa taaacaggca ggccagtggt
     8341 cgattaagcc ataagaaaga gcttagtgtc aggacaatat taatcacgct gaaagcgacg
     8401 accggcatcg acaagaaaac cagtacgtta tgcagcgaat ccagcggcag cgcctgcaac
     8461 acctgtttaa aaaaggcaat attcaggtag atagagatat aaaaagcggc caacaatagc
     8521 caggcgagta aattcaaaga gggtcttttt agtaggcgct tcaacatcac ggtgtttcca
     8581 tcgaacaaag tgcgcatatg ctcgcaaagc aaaattaagc caaccttaag ttcttaaggt
     8641 tggcttttat gtttgctgga ttaaggggaa ttaatctttg cttattggtg catctaaggg
     8701 atacgggttt ttatgtagcc ggttgtaatt cagcgcatac atggcggtga tgaccatcag
     8761 ggtgacaaat gaccacataa cctctttcgc tccggacccc accacggccc agatgcagta
     8821 gaggaaggca atggtagtaa ctgccagata tgccgggcgt gctttaccaa agtgaccgtg
     8881 tccgagcagc agtaacgccg cacaggtgta aagatatggc accagtgtaa agatgaccga
     8941 gacggaagaa accagaccga actctttggt cgcgtttggt gaaatgctgc tgagctggaa
     9001 gatggtcatc aaaataccga cgataatcag ccccgccact ggcgtacccg ctttatttac
     9061 acgggcaaaa atcggtggga acagtccgtc atcggcagcg gctttcgccg tttgacccgc
     9121 cagcaacgtc cagccgccca gtgaacctaa gcaacccgca gctgcgcaga aggaaacaat
     9181 ggccccggcg gtgtcaccca acgccatccg tgcggcatca ccgaatggcg aagcagaaac
     9241 gcgcagtgcg gcattaggga tcatccccat aatcgcggtg gtagaaagta catagcaaac
     9301 ggcggcaatc aataccccac caatggtggc gatagggaca ttgcgtttcg ggtttttcac
     9361 cacacctgcg gcaacggagg cactttccac accgatgaac gaccacagcg taacgttaag
     9421 ggtactttga attgcaccga aggtgcccag gccgctgacg ttccatgccg ccatataggt
     9481 ttcaccacgg aaccagaacc agccaaatac ggcaatcccg acgatgggga tcagcgccag
     9541 cacggtggca actgcctgca cacgggtgat cattttcgga ccgacaatgt tcagcaggac
     9601 gaagatccac agcaccacga cgcaggtgat ggttaatacc aatggatctt tcagaatcgg
     9661 gaagaagtaa cttaaatatc ctacgccaat gaccaccatg gcgatattgc cgatccagca
     9721 ggccagccag tagaggacgt tggtttgata accgagaaac gggccaaagc agcggcgggc
     9781 gtaagcgtaa gaaccaccag gacttgggtc gaggaacgac attttggcgt ataccatcga
     9841 gagccccagt gcaccgataa tcgtcaccaa ccatccataa atggcaatcc cgccagtaga
     9901 ggccaggttt gcaggtaaca gaaaaacacc tgaccccata atattccccg acaccatcag
     9961 ggtgacgggg attaagccca ctttgtgagc atcagcatcc gaagacataa ttaaactcct
    10021 gcgaaggcga gcttcgtgac aataaattac gtcatatcat acgcctgcat tcgatagttg
    10081 aattattatc gaccgggtta tcgctgatgc cgttattaat atagctcttc gttaaggtta
    10141 aaaatcaggc gacagtgcgt tctctgtgct gactaacata atgcagcggc gtcataccgt
    10201 agaagtcttt aaagacagaa ataaagtacg acgtactgtt gtagccgcag gactgtgata
    10261 cctgagagat atttttaccg tccatcatta attcatttac ggcataacgc atgcggcagg
    10321 tggtgattat ttggctataa ctggtgtttt cgcttttcaa ctttttcttt aacagacttg
    10381 ggctaagaca taaacaactg gctaccatac taagattcca gtctttgtga atatcgcttt
    10441 caataatttg ataaacgctg tcacttacac aattacgtaa catatacatc attaatgaaa
    10501 cgaatttttt actgtcgaga aaacgggata gcaccgtgaa taataatgcg cgtgttcgtt
    10561 ccttttctga ctcagtttct gcgggcatca tgctgtgttg cgcggcaacg cgaaagacgt
    10621 ctggcgtcag gcatggcagg gtgagtatgg gcgtagcgct acgttgccat actggtattt
    10681 gcgagagatc tttattcaga aaccggaggt aatctttgat gatgtcgtga ctaatatgag
    10741 caaccaaagt gttgttaaga gaggagacgt cgataatatt attttcacaa tttaataacg
    10801 ccatatggtt agctttaagg ctaataggtt ctttcccatt cacccttatc cagacatctt
    10861 tttcagtcaa taaaacaata caaggttggt cgctgcaaat cctcatacat gtactcctga
    10921 gtgcgaataa aagaccagtt ctcgctaaag caaagcgata ccgggaaatg gttatataat
    10981 tgtatgatga atataaacat gcataaaaat aacgagtttt actaatagta caaattttta
    11041 tagtaatttc tcatgtacat atttttttac aggataaata acaggcaaaa aaaagcgcgg
    11101 ggtggggccg cgcaaaaagt atgacatttt tgtttgcagc aatttttatg aaaacgttgc
    11161 catactcaaa aggcctaagg ccaggcggcg taatgttatt taaacaatta cgccttcagc
    11221 ggaatagtgg ttacgctttc acgcacataa cgtggtaaat accgtcaata atttcagtcc
    11281 cttcagtttc gtgttcaaat ccagggaaat ggtggtccca ggattgcagc gagcgtaaat
    11341 aacttacttg cggactgttt ttatcgccga agttttcacc agacagcagc atcgggattc
    11401 ctggcggata cgggataact gagtttgccg cgatgcgtcc tggcagattt tcaatggata
    11461 ccagttcgac attgttgtcg acaatcgcgt tgtacgcttc acgcggggtg acttccgcca
    11521 ccggcaggcc ggaataggct tcgttcaacc gtgcgccagg gttgttttct ttcagccagg
    11581 caaacatggt gtcacccaga tcgtgaatcc ccatgttcgc gtaagtgtca ggatattgtt
    11641 caacaagttc cggcatcacc tgcgccagcg gtgtgttggc gtcatagtgg cgtttgaagg
    11701 agcaaagggt gttaaccaga gttccccatt tcccacgggt tacgcccata gagaacagga
    11761 acataatttg gaagtcagtg gtgcgggtag gtacaatgcc gtggcgacca agccaggcag
    11821 tgaccagcgc cgccggaaca ccggtttctt ccagttcacc atcttcaccc attcccggag
    11881 caaggatgct gactttaatc gggtcgagca tactccagtt atccggaata tctttgaagc
    11941 cgtgccagct ttcgcccgga tgcattaccc agcagtcctg aacggtggtc agcagtttgg
    12001 ttggtgcgtc agcaaagtca taggttttgc cggtttgtgg gtcggtgacg acttctttgt
    12061 tccacggttt gaagaaccag ctaccgtcag cggtgaactc tttatatagc cgcgccatcg
    12121 cctgacggaa atcaaccgct tcgtcaatca cttcctgtgt cagtgacagg ccgctgttgc
    12181 cgtccatcat cgacaccgcc acgtcgttgg atgcgcagat ggcatacagc ggggaggtgg
    12241 tggcatgcat catgtaggcc tggttgaagc gggagaagtt aatcgcccca cgaccttcac
    12301 gtacatgaat ataagaagcc tgtgacagcg cattcagcag tttgtgggtg gagtgggtgg
    12361 cgaaaacggt aggaccgttg tgatcgccag gttcgccgcg catggcatag tgatcggcat
    12421 agatcgggtt gaaacgtgca tagccgtacc aggcttcgtc aaagtgcaga cgatcggagg
    12481 ttttttccag cagatcctgc gcttctttag cgttataaca cacgccgtca taggtgcagt
    12541 tggtcaccac gcagtaagac ggtttttgcc cggctttgtc tttggtcagc gggctttcac
    12601 tgattttctt ctgcaaggtt tcaggttgca tttcctgcgg atagattggc ccgataatgc
    12661 cgtagcggtt gcggcttggc accatataga ccggtttcgc gcctgtcagc atcaaacctt
    12721 gttcgatgga tttatggcag ttacggtcaa cgaccacgac atcgttatcg gtcatgcaag
    12781 cctgcatgat ggtgcggtta gagccggaag taccgacgac taccgaccag gagcgatcgg
    12841 caccaaatac gcgtgcggca tatttttcgc tttcgccaaa tgcgccagta tggtcaagca
    12901 aagaaccgag ggaagttcgt tcgatgccca tgtcggtgcg gaacagattt tcaccatagt
    12961 agtcatggta gaaacgtccg gcgggtgttt tggtaaaacc aacgccgccc tggtggcctg
    13021 gcgctgccca ggaatattca tggatgtcac tatatttcat cagcgcgctg aacagtggcg
    13081 gcaacagctg ctggcggtag cgggtcatcg cggcaacggc gcgtccggcg ataaagtcgg
    13141 cggtatcttc cagaatccag gcgaattcat cgacaagctc cagcaggtcg cgatccattg
    13201 cggcgagggc tttttcccga tcgcccaaca ggaagaccgg cacgttttgt tggcgctcat
    13261 gaagcttacc gatcaattgt ctgacgtttt gatgttcgtc cggatgttcc atttgatagc
    13321 tgaacatcag gcagtcaatg gcttcgtttg aagagagaat ggcaaaacca tcatcaaagg
    13381 aggtggattt aatcacggta acattttgct ggcttaaagc atctgccaga cgctcaacgg
    13441 cgttaccgac ccaggtgtct tgatggagaa actcgctttc aacaattaat actttcatca
    13501 ttgcttaccc ggttatgaag gaatcttcgt tgcgggcaag tatcttccgg ccttttcggg
    13561 ctgtaaagcg cgtgaaaaac aaacattttt gaaatattta gttttataaa caatacgtta
    13621 tgtgattatt ttaaattatt ttcactgctt attatcgacg gctaaactat ttttttggct
    13681 gatactgata tcgtctttag ccgggaaacg tctggcggcg ctgttggcta agtttgcggt
    13741 attgttgcgg cgacatgccg acatatttgc cgaacgtgct gtaaaaacga ctacttgaac
    13801 gaaagcctgc cgtcagggca atatcgagaa tacttttatc ggtatcgctc agtaacgcgc
    13861 gaacgtggtt gatgcgcatc gcggtaatgt actgtttcat cgtcaattgc atgacccgct
    13921 ggaatatccc cattgcatag ttggcgttaa gtttgacgtg ctcagccaca tcgttgatgg
    13981 tcagcgcctg atcatagttt tcggcaataa agcccagcat ctggctaaca taaaattgcg
    14041 catggcgcga gacgctgttt ttgtgtgtgc gcgaggtttt attgaccaga atcggttccc
    14101 agccagagag gctaaatcgc ttgagcatca ggccaatttc atcaatggcg agctggcgaa
    14161 tttgctcgtt cggactgttt aattcctgct gccagcggcg cacttcaaac gggctaagtt
    14221 gctgtgtggc cagtgatttg atcaccatgc cgtgagtgac gtggttaatc aggtctttat
    14281 ccagcggcca ggagagaaac agatgcatcg gcagattaaa aatcgccatg ctctgacagg
    14341 ttccggtatc tgttagttgg tgcggtgtac aggcccagaa cagcgtgata tgaccctgat
    14401 tgatattcac tttttcattg ttgatcaggt attccacatc gccatcgaaa ggcacattca
    14461 cttcgacctg accatgccag tggctggtgg gcatgatatg cggtgcgcga aactcaatct
    14521 ccatccgctg gtattccgaa tacagcgaca gcgggctgcg ggtctgtttt tcgtcgctgc
    14581 tgcacataaa cgtatctgta ttcatggatg gctctctttc ctggaatatc agaattatgg
    14641 caggagtgag ggaggatgac tgcgagtggg agcacggttt tcaccctctt cccagagggg
    14701 cgaggggact ctccgagtat catgaggccg aaaactctgc ttttcaggta atttattccc
    14761 ataaactcag atttactgct gcttcacgca ggatctgagt ttatgggaat gctcaacctg
    14821 gaagccggag gttttctgca gattcgcctg ccatgatgaa gttattcaag caagccagga
    14881 gatctgcatg atgtctgcac ccaaaattac atttatcggc gctggttcga cgattttcgt
    14941 taaaaatatt cttggtgatg tgttccatcg cgaggcgctg aaaacggcgc atattgccct
    15001 gatggacatt gaccccaccc gcctggaaga gtcgcatatt gtggtgcgta agctgatgga
    15061 ttcagcaggg gccagcggca aaatcacctg ccacacccaa cagaaagaag ccttagagga
    15121 tgccgatttt gtcgtggtgg catttcagat tggcggttat gaaccttgca cggtgactga
    15181 tttcgaggtc tgtaagcggc atggtctgga acaaaccatt gccgatacgt tggggccggg
    15241 cggtattatg cgcgcgctac gtaccattcc gcatctgtgg caaatttgcg aggacatgac
    15301 ggaagtctgc cccgatgcca ccatgctcaa ctatgttaac ccaatggcga tgaatacctg
    15361 ggcgatgtat gcccgctatc cgcatatcaa acaggtcggg ctgtgccatt cggtgcaggg
    15421 aacggcggaa gagttggcgc gtgacctcaa tatcgaccca gctacgctgc gttaccgttg
    15481 cgcaggtatc aaccatatgg cgttttacct ggagctggag cgcaaaaccg ccgacggcag
    15541 ttatgtgaat ctctacccgg aactgctggc ggcttatgaa gcagggcagg caccgaagcc
    15601 gaatattcat ggcaatactc gctgccagaa tattgtgcgc tacgaaatgt tcaaaaagct
    15661 gggctatttc gtcacggaat cgtcagaaca ttttgctgag tacacaccgt ggtttattaa
    15721 gccaggtcgt gaggatttga ttgagcgtta taaagtaccg ctggatgagt acccgaaacg
    15781 ctgcgtcgag cagctggcga actggcataa agagctggag gagtataaaa aagcctcccg
    15841 gattgatatt aaaccgtcac gggaatatgc cagcacaatc atgaacgcta tctggactgg
    15901 cgagccgagt gtgatttacg gcaacgtccg taacgatggt ttgattgata acctgccaca
    15961 aggatgttgc gtggaagtag cctgtctggt tgatgctaat ggcattcagc cgaccaaagt
    16021 cggtacgcta ccttcgcatc tggccgccct gatgcaaacc aacatcaacg tacagacgct
    16081 gctgaccgaa gctattctta cggaaaatcg cgaccgtgtt taccacgccg cgatgatgga
    16141 cccgcatact gccgccgtgc tgggcattga cgaaatatat gctcttgttg acgacctgat
    16201 tgccgcccac ggcgactggc tgccaggctg gttgcaccgt taaaacgcga ctaaacgcta
    16261 ctgcgccggg ggatttattc cggcgcacac ctctgacgat accaataaca gaaggcgggc
    16321 gttggtaaca gcgacccgat accctatgag catttcaatg actacaaaac tcagttatgg
    16381 atttggagcg ttcgggaagg attttgcgat cggcattgtg tatatgtacc tcatgtatta
    16441 ctacaccgat gtcgtcgggc tgtctgtggg tttggtcggt actttgtttc tggtggcgag
    16501 gatctgggat gctattaacg atccgattat gggatggatt gtaaatgcta cgcgatcgcg
    16561 atggggtaag ttcaaaccct ggatcctgat cggtacgttg gcaaactctg taatcttatt
    16621 tctcctcttt agtgcgcatc tgtttgaagg tactactcag attgtctttg tttgcgtgac
    16681 ctacatcctc tggggcatga cttacaccat tatggatatt cccttctggt cgctggttcc
    16741 aaccatcacg ctcgataaac gtgagcgcga acaactggtt ccttatccgc gtttttttgc
    16801 cagtctggca ggctttgtta cggcaggtgt gacgctacca tttgttaatt atgtcggcgg
    16861 tggcgatcgg ggatttggct ttcagatgtt cactctggta ctgatcgcct tttttattgt
    16921 ttcaaccatc atcactctgc gcaatgtgca tgaagtcttt tcgtcagaca atcaaccgtc
    16981 tgctgaagga agccatctga cacttaaagc catcgttgcg ctaatttata aaaacgatca
    17041 gctttcatgc ctcttgggta tggctcttgc ttataatgta gccagcaaca ttattaccgg
    17101 ctttgctatc tattatttct catatgttat cggtgatgcg gatttgttcc cctattatct
    17161 gtcgtatgcg ggagctgcta acctggtgac gttagtattc ttcccacgct tagttaaatc
    17221 attatcccga cgcattttat gggccggagc atctattctt ccggtgttaa gctgtggtgt
    17281 tctcctgtta atggcattaa tgagctatca caacgtcgtc ctcattgtga ttgcgggtat
    17341 tttgctgaat gtgggaacgg cgcttttctg ggtattacag gtcatcatgg tggcagatat
    17401 cgttgattac ggtgaatata aactgcacgt acgctgtgaa agtatcgctt actccgtgca
    17461 gactatagtg gtgaagggcg gttcagcctt tgcggctttt ttcattgcgg ttgtgttagg
    17521 gatgattggc tatgtaccga atgttgaaca gtctacgcaa gccctattag gtatgcagtt
    17581 tattatgatt gctctaccaa ctctgttttt catggtaacg ctgattctct acttccgttt
    17641 ctatcgcctc aatggtgaca cgctgcgcag gatccagatc catctgctgg ataaatatcg
    17701 caaagtaccg cccgagcctg ttcatgctga tattccggtc ggtgcagtga gtgatgtgaa
    17761 agcctgacgt ggacaatagc taacgaaaat ggcctgatgc gatatgttta tcaggccacg
    17821 tcttaatgta atgctttgga tttgcaaatt ttgtagaccg gataaggaat tcacgccgca
    17881 tccggcatca acaaagcgca agttgttatc cggttatcaa gccaaagcgc cgtagctggc
    17941 ggcaatgaaa gcgagcgagg aatatcaccg tcgttaatgc gccaagcagc gcgcagaaca
    18001 tatcggattg cgtgtcccac tggtcgccct gggtgccgag aaaatcatcc gctccctgac
    18061 ccattgccag cgctgcccac cactcgatta attcatacat cgcgcttatc gccagcgcca
    18121 cgcagcagac caggaacgcc accattttac gtccgcgcac gtacatcccg cgaacgagaa
    18181 tttctcgtgc caccagtgca ggcaccagcc cctggaaaaa gtgccccagc ttgtcatacg
    18241 gattacgact caaccccagc cattcctgca cctcaaaacc aacggggact ttcgcgtagg
    18301 tgtattgtcc gccgaccatc aggatgatgg cgtgaaggaa aatgagcgta tagagcagcg
    18361 gcgttaacgg ataacgtctg gcggtggcaa gcagtagctg cacgacaata atcaccggtg
    18421 tcacttccat cagccaggtg agtttgtcat gggccgaaat gccggtataa atcaggatta
    18481 acgttagcgt cagtgcgctg gtgttaagaa ttaacggctt gagtgtgcgg gtcatggtga
    18541 gttcgcaaat cagggaaaat actgactatt caccagcaag cgtgaaatta caatcgcaaa
    18601 agaggtggcc cagggggatc acctggcagc atgctgccag gcgctgggcc gaagaggtta
    18661 cttagtgcag ttcgcgcact gtttgttgac gatttgctgg aagaagtcgt tacctttgtc
    18721 atcgaccagg ataaacgccg ggaaatcttc tacttcgatt ttccagatag cttccatacc
    18781 cagctccgga taagcgacgc actccagatg cttgatgctc tgctgcgcca gtaccgccgc
    18841 cggaccgccg atgctaccga ggtagaagcc gccgtgttta tgacacgcgt cggtaacctg
    18901 ctgactgcgg ttacctttcg ccagcatgat catgctgccg ccgtgggatt gcagcagatc
    18961 cacgtaggag tccatacggc ctgcggtggt tgggccaagt gaacctgatg gataaccggc
    19021 aggggttttc gccggacccg cgtagtagat cgggtgatct ttgatgtact gcggaagttc
    19081 tttaccggcg tcaatcagct ctttcagctt ggcgtgtgca atatctcggc ccacgataat
    19141 ggtgccggtg agcgacaaac gagtggatac cgggtattgc gaaagctggg cgaggatctc
    19201 tttcatcggg cggttaaggt caactttcac cgcttcgcct tcaccggcct ggcgcagttc
    19261 ttgtggaatg tactggcctg ggttgtgttc cagtttttcg atccagatac cttcgcggtt
    19321 gattttcgct ttaatgttac ggtcagcgga gcaggagacg cccatgccga ccgggcagga
    19381 tgcgccgtga cgtggcagac ggataacgcg aatgtcgtgc gcgaagtatt taccgccaaa
    19441 ctgcgcgcca agaccgagtt tctgggcctc ttccagcagt tcctgttcca gctggacatc
    19501 gcggaacgcc tgaccatgtt cgttcccttc cgtcggcagt tcatcgtaat agtgagcgct
    19561 tgctaacttg acggttttca ggttggtttc cgcagacgta ccgccaatca caaacgcgat
    19621 atggtacggc gggcaggctg cagtaccgag ggtacgcatt ttctcgacga ggaagttttt
    19681 cagtttgccg ggagtcagca gggctttggt ttcctggtag agatacgttt tgttggcaga
    19741 gccgccgcct ttcgcaacgc aaaggaattt gtactcatcg ccatctaccg cgtacaggtc
    19801 gatttgcgca ggcaggttag tgccggtgtt gacctctttg tacatgtcca gcgccgcatt
    19861 ctgtgaatag cgcaggttat cttcgatata ggtgttatag acgcctttcg acagcgtttc
    19921 ttcatcaccg ccgccggtcc acacgcgctg gcctttttta ccgacgatga tcgcggtgcc
    19981 ggtatcctgg caggtcggca gcacgccttt ggcggcgatt tcggagtttc ttaagaattg
    20041 cagcgccacg tacttgtcgt tttcgctggc ttctggatcg tgaagaatag ccgcaacctg
    20101 tttctggtgt gccgggcgga gcataaaaga agcgtcgtga aaggcttgct gcgccagcag
    20161 ggtcagggct tctggttcca ctttcaggat ggtttcgccg tcgaagtcgg caacgctaac
    20221 gtaatcggaa gtgagtagat agtattcggt attgtctttc cccatcggga aaggtgcctg
    20281 gtagataaag ggtttgtttg acatagcttc cagcctgtaa ctctgtattt gttattcgaa
    20341 aatggcgtgc cgcgtagtca cgggcggcac gcaaagtgca tttataagaa cccgtacatc
    20401 gcggcgaaga tccagccgaa gacgcacgat acgctcacac caatcaaccc cggcagaata
    20461 aagctgtggt tgatgacgaa gcgaccgatg tgggtggtgc cggaacggtc aaactgaatc
    20521 gctgccagat cgctcggata agtcggcagg atgtaataac cgtagcaagc cggtgctgaa
    20581 gccacgatgt atgccggatc aacgccgatc gccagcgcga ccggaacaat cgccgccagc
    20641 gccgcagcct gagagtttac aaacttggaa accagcagca gaacaatggc ataggcccac
    20701 ggatactctt tcaccatttc acccagtacg ccctgaattt cagacatatg cgcaccgaac
    20761 atggtttctg ccatccatgc gataccgtac accgccacga tggcgatcat accggaacgg
    20821 aagacttcgt tttttgagat agacgcggga ttggttttgg tcaggataat aatcagcgcc
    20881 ccggtcagca gcataaacat ctgaataacc agtaccatcg acagcggttt gccgccgaag
    20941 gatggacgca ggtccgaatc agcaccaaga agggcgacta cagcgattgc cccgaggaaa
    21001 atccacattg ccagccagtt gcttttcggc agttttttat ccagcagcgt cgcggtatca
    21061 ccgtaaacat actcacggtt ttccggtacg gagatgaatt tctggaactc ttcgtcttta
    21121 tccagatctt taccgcggaa ccagctgaag ataccgatcg ccaggatacc gattaacgtc
    21181 gatggaatgg tgattgccag cagatcgagg aactcaagat ggcgaccatc aaaggtgaca
    21241 ttacccagca tcgcaaccag agacacgacc gcaaccgaca ccggactggc gataatcccc
    21301 atctgtgcac cgatagaact tgccgccatc ggacgttccg gacggatgtt gttcttaatg
    21361 gcgacgtcgt agatgatcgg cagaatggtg taaaccacat gacccgtacc gcaaagaatg
    21421 gtcagtgtac aggtcacaaa cggcgcgaca attgagacat atttcgggtt gcggcgcagc
    21481 agcttctcgg caatttgcag catgacatca agaccgcccg aagcttgcaa ggtcgccgat
    21541 gccgccacca ccgcaatgat aaccagcatg acatcaactg gtggtttacc tggctgaagg
    21601 tggaagacga agaccagaat gaccagaccg ataccgccta ataaacccag cgcgatacca
    21661 ccctttctgg caccataaaa cagacatatc agtattatga taagttggat agtaaataac
    21721 atgtgtgaac cctcgcgata atcctattta aatttttgct gaatagatca cagtcacgtt
    21781 ctgttttgta tgaactgttt tcagagcctg actaaatatc cgtttggtcg ttaccggctt
    21841 tagcaaatac ctcacagtga atattggctg attaaagcag cggcaaattt atgcactgtg
    21901 ataagcggct ttttcagaga gaaagactct ctggcgatgg gtttatagtt tgtactgcgc
    21961 agatgttaat gttttgtttg ctgttatctt attgatattt atcggtctat tttttgttct
    22021 cagggcagat gtcattaggt ttatagatta atctgatcta cccatttgtg ggtaaaaata
    22081 cacataatgc gggtgacata atagttaatt aacttttgtt agcgttttga aattaaaaac
    22141 accgttcacc tgaagagata ttaattttta gcgatgatgg agggataatt atatttgatc
    22201 tggcacaagt tttactgatg aaggatgtaa cttgtgccag gggtattttg cattacggta
    22261 ataattatta cttacagata accagcgatc cgttattggc aatattgttt cagtagtgag
    22321 tagtgttctg cctgaatacg gtaacggtaa actggacgcc ccgtgacgcc ataatggata
    22381 ctggtgaaca agatgtggca gttgaccagc cagatgaggt atttacggca ggaaacacgc
    22441 gaaatgttaa cctcgttggc tagctcgtcg gttgaaaatt catagtcctg atgcgcgtca
    22501 atccactggc acagtgtgcg taacgtctgc ggcgttaagc cttttggcaa gcgacgagga
    22561 tcctgttcgt tggagctgct gccgtggatt agctgatcaa gctcggcctg gtcataatac
    22621 tgatgttttt ccagcgccat tttcttttgc cgccagccgg tgagcgcctc ttcaaagcgg
    22681 gaagcctgga agggtttgat caggtaatcc acgacaccgt aatgcagcga atctttaatg
    22741 gttgccgcat cggctgcgga ggagatgaca atcacatcac ttttgcaacg cgcgttatgc
    22801 aggacaggca gtaaatcgag cccgttctct ttttgcatat agatatcgag caatatcagg
    22861 tcgataggcg tatcgctatt gaagataatc tctttggctt tctccagcgt cgaggctgtt
    22921 ccacagcatt gaaagcctgg gatttgtgct acgtatcggc gattcagctc cgcgaccatt
    22981 gcgtcgtcat cgataattaa tacattgatc atctgttcga cctctccccg tcccagggta
    23041 tctggacaaa aaattgtgtg aaaatcccgg gttccgattc cacggcgatg ctgccgccga
    23101 gattttctac ctgttgtttg acaagtgcta aaccgacgcc tcgctcgctt ccttttgtcg
    23161 agacaccttt gtcaaaaatg tgatcgattt tatcgggtgc gatccccggt ccatcatcat
    23221 taacttcaca gtgcagccag ccgtgacggt agtgcaatgt tacgctaatt tcgcctccgg
    23281 gttccggccc taatgcctcc agcgcgtttt ctatcagatt tcccaacgtg gtaatcagcg
    23341 tcgcgacctg gtcctcactg ccgctgtctg gcagctggct ttcactgttt aaaatcagcg
    23401 tatggcctaa atcggtcgcg cggttaatct tgctgattaa aaaaccagcg ataaccggag
    23461 atttgatctt acccagcaga gagccaatct cttcctgata gttattggct gttttgagaa
    23521 tgtaatcttc caactgctta taactcttca gatgcaataa tccgagaatc acatgcaatt
    23581 tattcataaa ttcgtgggat cgttcacgaa gtgcgtcagc atagttgacc agaccgtcga
    23641 gtcgctgcat cagtttacgt acttcagttt tgtccctgaa ggttgaaatg gcaccgatga
    23701 taacgccatt actgcgcacc ggaacggtgt tgatcagtaa tagccggtct ttaatcgtaa
    23761 tctcttcgtc gcggcgcggg gtaccgtcgc gtaacacttc cgagacatct accacctgtg
    23821 accatgagtg gcttagcgtc gacagtttct catcgtcctg cgacttacgg taattcagca
    23881 attcttgtgc ggcatcgttg atcagcgtga cctcgccgcg atcgtccacg gcaacgacgc
    23941 cttctttgat agactgcaac atggcctggc gttgctcaaa cagcgtggag atttcgtagg
    24001 gttccaggcc gaaaaggatt tttttcagta ccttaaccag aatgcaggtg ccaatcagtc
    24061 cgaccagcat gccaaataat accgaccaga taatgctcca gcgactgtca ttgatctgtt
    24121 gggtcacacg gcttaactca aggccgatcg ccaccacgcc aatttgttta tgattttcat
    24181 cgtagatggg ggtaaatacg cgtaaagcct gcgccagaaa accgcgattg atagcgacat
    24241 tttcttcgcc attcagcgct ttaaggatgt catcaccttt aaatggctga ccaatacgct
    24301 gggcttcagg atgcgagtag cgaagacttt gcatatcggt aacgacaata aacagcagat
    24361 cgttgcgttt gcgtacggct tccgcgatgg cctggatgcc actctcctgc ggttttttct
    24421 gcaagccctg acggatttcc ggcgagtcgg cgagggtacg cgccactgcc agtgccttgt
    24481 tggctagccc atctcgcgtc atatcactga tttgcgagaa gtaaatcaga tgcaccacca
    24541 atagcaccga gaacagtacc gcactgacca ttaagatcac tgtggtactc aatttcatcg
    24601 gacgtttgcg taacatgcgg tagggcaatg aatgtctcat cagcttcctt gtgtgacaaa
    24661 tttcttaagc attatctctg atgaggcggg taattcaaag ggagtaagaa tgattggcta
    24721 tataggggaa gagactctgg caacggaaac tgccagtgct gtatgaagat tccggggcta
    24781 tgcttatagc gataatcata ctgatgagag agggaaggtc atggatcagg cgctactgga
    24841 cgggggttat cgctgttata ccggcgaaaa gatcgatgtc tatttcaaca ctgcgatatg
    24901 tcagcattct ggcaattgcg tacgtggcaa cggcaagtta tttaatctca aacgaaagcc
    24961 gtggatcatg ccggatgaag tcgacgtcgc cactgtggtt aaagtgattg atacgtgccc
    25021 gagcggcgcg ctgaaatacc gtcataaata agcgagggta aaatggaaat acgcgaaggc
    25081 cacaataaat tttacattaa tgacaaacaa ggcaagcaaa tcgctgaaat tgtctttgtg
    25141 ccgaccggag agaatttagc gattatcgaa cataccgatg tcgatgaaag cctgaaaggg
    25201 caagggattg gtaaacagct ggttgcgaaa gtcgtggaaa aaatgcgtcg ggaaaaacga
    25261 aaaattatcc cattatgccc atttgcgaaa catgaatttg ataaaacgcg ggagtatgat
    25321 gatattcgca gttgatggga gagtacagag tcacgatatt tttcattctc tccgcgatgt
    25381 gatgcaggag agcatctgaa gggtaggggg atgcacaaag aatgggcaga gagcgcgttt
    25441 ttttgtccca agtcatcccc tttactgagc aaaaaaaaga atatctccta tatgagaatc
    25501 atcaatcggg gttaataagt tttgcgtccc cagagcgttt aatattgata ggagtcatat
    25561 tatggaaggt aaaaacaagt tcaatactta tgttgtttct tttgattatc catcatctta
    25621 ttcctcagtg ttcttaagat taagatcatt gatgtatgat atgaatttct cctctatcgt
    25681 ggctgatgaa tatgggatac cacgacaatt gaatgaaaac tccttcgcaa taacgacatc
    25741 gttagccgca agtgaaatcg aagatttaat caggctcaaa tgcttagact taccggatat
    25801 tgattttgac ctcaacatta tgacagttga tgactatttc cgtcagtttt acaagtagcc
    25861 aggaaggata agaagaacat aaaaaatggc actattctct aaaatattaa ttttttatgt
    25921 gattggtgtg aacatatcct ttgtcattat ctggtttatc tcacatgaga aaacacatat
    25981 tcgtttactt agtgcattcc tggtcggaat aacctggcca atgagtctgc ctgtggcatt
    26041 acttttttct ctcttttagg agctgtagtt gagtggaccc gctggttatc gtgaaacgaa
    26101 gcgtctctcc tcaaaactgg atttgcggaa cgatgaacga agcagtcgcc tgactgcttc
    26161 gttcattaaa gtgaaattta tttctgtggg cgcatcgccg ggaagagaat aacgtcgcga
    26221 atagtatggc tgttagtaaa cagcataatc attcggtcga taccaatacc cagaccagcg
    26281 gttggcggca gaccatattc cagcgcagtc acgtaatctt cgtcatagaa catggcttcg
    26341 tcgtcacctg cagctttagc attaacctgt tcctggaaac gttcagcctg atcttctgcg
    26401 tcgtttaatt cgctaaaacc attaccgatt tcacgaccac cgatgaagaa ttcaaaacgg
    26461 tcggtgattt ccgggttaac atcattacgg cgtgccagcg gggacacttc tgccggatat
    26521 tccgtaataa aggttggctg aatcagatgt gcttctgcca cttcatcaaa gatctctgtg
    26581 acaatacgtc ccaaccccca gcttttctct accgtaatac cgatagattc agctaatgct
    26641 ttagcagcat caaaattatc caggtcggcc atatcggttt ctggacgata ttttttgatt
    26701 gcttcgcgca tggtgagttt ttcaaacggt ttgccgaaat caaacacatg ctcgccataa
    26761 gtgactttag tggtacccag aacctcttgt gccagggtgc ggaacagtga ctctgtcagt
    26821 tcaatcaaat cgtggtaatc cgcatacgcc atgtagagtt ccatcattgt gaactcagga
    26881 ttatggcgaa cagaaatacc ttcattacgg aagttacggt tgatttcgaa tacccgttca
    26941 aaaccgccta caaccagacg tttcagatac agctccggcg cgatacgcag atacatatct
    27001 aaatccagag cattatgatg ggtaataaac gggcgagcag atgccccacc tggaattacc
    27061 tgcatcatcg gggtttctac ttccataaag ccgcgcgcga ccatgaattg acggatagcg
    27121 gccagaattt ttgaacggac aacaaacgtt tgacgggatt tatcgttagc gatgaggtcc
    27181 agataacgtt gacgataacg gacttcctga tcctgcagac catggaattt atctggtaaa
    27241 ggacgtagtg ctttagtcag caggcgcagc tcagtacagt gaatggaaag ctcacccgtt
    27301 tgcgtcttaa acagcgtacc gcgggcaccg ataatgtcac ccagatccca ttttttaaac
    27361 tgatcgttat aaacaccttc tggcaggcta tctcttgcaa cgtacagttg aatacggcca
    27421 ccgacatcct gcaacgttac aaaggaggct ttccccatga tacgacgggt catcattcgg
    27481 ccagcaaccg agacttcaat gtttaaggat tccagttcct ggttatcctt cgcatcaaac
    27541 tcttcgtgca actggtcaga ggtatggtcg cggcgaaaat cattgggaaa cgccacacct
    27601 tgctgacgta gtgccgccag tttttcgcgg cgatttctca gttcatcgtt aaaatcaata
    27661 gcctcattgg ctccccgtgt ttcttgttca gacattttgg ttcctctaaa tccagctttc
    27721 aatttagcgt agataaagag acagatcggt acactgtatt atctgcctcg actattagta
    27781 actcagttta tcttatcgaa actaacgctt acctcaagtt gatatcacta ataaataacc
    27841 atcaaaatgg tttaaatgac ttattaatct cgatttgtta gtgttataaa ctgaaagtta
    27901 atttattcat aaccaattgt ttttacgaca gttaatcgtt gctctcctgt atcatattcg
    27961 tcggcgtgct aaacagaaaa cgggtagcaa aggccaatac gacgatgatc gcgacacaag
    28021 ccaacgtcca ctctcccatc tgagaaaaga atcgctggta agctgcaatt gccataccgc
    28081 taatttgcga ctctgtcgtc tgctgtgcca cgacgcctgc cagccagttg gcgaccgcgc
    28141 ctgttgccag catataaatc ccggttaata cgccagacat tttcagacgc gtgatttgcg
    28201 caatcgccac cgggtcaata aagagttcgg caaagcccat tagcgccagc ccggatatca
    28261 tcacgcccat tgacgcttga ccgtcagccg ctgcatgtcg ggcatcaaat gccaacaaca
    28321 taaagccaca agccatcagc agtaagccaa aggcaaactt cagccagacg cgcaatgttg
    28381 agttgccgcg gctttctggc gacgccagcc aggccagtac aaccccagcg agcatcaccg
    28441 caattgcatt caccgactgg aatagtgctg taggtacttc aatattgaat gcctgacgat
    28501 tcacaaagcg atcgataaac aagctgatgg tactgccgcc ctgttgtgcc agtacccaga
    28561 acaatgtccc gacaaacatc aacaatacaa tttgccaaag agcacggcga tgttcgggga
    28621 atttgatcat catgcgggca atgatttgtg cggcaatgag gcaaacgatc gccagcaaat
    28681 atccggacca gtcgttctcc agcagcagag taaaaaatac tggggctaaa cagagcatca
    28741 ccactaacca gctccatact ggtaaggcaa atttgacact agtgagcgct tttttatcca
    28801 tactacgtgt ggactggaaa tgacgatgac cgcttaagaa aatcaacaaa ccgataaaca
    28861 tgccgccacc cgcaagggca aagccaacat gccatccata ccactgagca gccaggccgc
    28921 aggcgattgg ggctgcgata gaaccgatat tgcccgcagc atacagcagc gaaaaaccgc
    28981 catcacgtcg atgatcgttc tcgtcgtaga gctcgccaag caaacagctg atgtttgatt
    29041 tgaataaacc gtagccacaa ataatgattg ccagcgccag atacaggcta aaggttgaat
    29101 ttgtatcaat acccagcacc acatggccaa gggtcattaa cagcgcgccg gcaatcactg
    29161 cagtgcggtt gccgagcagg cggtcggcaa gccagccgcc gagaataggg gtaacgtaaa
    29221 ccagagaagc atatgcgctg aacaggctga tggcatggtt atcatcaaaa ccaagctgat
    29281 gggtgagata gagaatgagt aaggcacgca tgccgtaaaa actgaagtac tcccagattt
    29341 ggatcgccac gatatagtat atcgcgcgcg gctgtgaggg tgttttcatg tgttctcctt
    29401 atgagcaaaa aagggaagtg gcaagccact tcccttgtac gagctaatta ttttttgctt
    29461 tcttctttca ataccttaac ggtatagcgg ccatcagcct gacggtatgc accgtgaata
    29521 tcggtttcaa agcccggata gtgagcgccg atttcacaca gcatctgcag gaactccaga
    29581 accggacggc tttcttcggt gatcatttca cccggcatta ccagaggaac tcccggcggg
    29641 tacggaagga tcatattggc gttaatacga cctaccattt cgtcgaggta aacttcttcg
    29701 gtcataccgt gcagctcttt ctggaatgca gcatacggag tcattaccat cgtcggcagc
    29761 acttcaaatg cgcgatacat cagatccggc agattgtggt gaacaatcag tttgtggata
    29821 ttctgagcca gttcctgaat acgcatgttt tcatagaatt caggatcttc acgatacaga
    29881 gacggcagca tgtttttcac acgcaggttc aggtcgaacg cacgtttaaa gtcagtcaga
    29941 gcacgcagca ggctcagtgc tttggtctta tcgataccga tgctgaacag gaacagcagg
    30001 ttatacggac cggttttctc aacaacgatg ccatgttcgt cgaggtattt cgccacgatg
    30061 ctggccggaa taccaaagtc gctcatggtg ccgtcttttt ccatccccgg agtcagcagg
    30121 gtgactttga tcgggtcaag atacatgtgc tcgttatcga tgtttttgaa gccgtgccag
    30181 gtgctgtcag aacgcagcgg ccagcattca gtcgtatcga tatgatccgg ctgccataca
    30241 tcaaagaacc agccatcaga ttccgttctc agacgtttga tctctttacg gaatttgatc
    30301 gcacgttcaa tagaaccgtt gatcagacgc ttacctgcat tgcctttcat catcgccgca
    30361 gcggtttcag tggacgccac gataccgtag tgcggagaag tggtggtgtg catcatgtag
    30421 gcttcgttaa aggtttcttc gtttacgtca cctttaacgt ggatcatgga agcctgagag
    30481 aacgccgcca gcagtttgtg agtggactgg gtttcgtaaa tcactttccc ttctacacgg
    30541 ccaccgctca taccgcattt accttcgtaa atcggtgaga agttggtgta aggcacccac
    30601 gcggagtcaa agtggatgga tttcacatcc agtgttttct tgatgaagtc ggtgttgtac
    30661 agcagaccat cataggtaga gttggtaatt acagcatgta ccggccaggt tgcgtttggt
    30721 gtttctttca cgcgcttagc aatggtagcg tgctggaatt cactctgtgg gataccacca
    30781 agaataccgt aagcgttacg ggtcgggcgg aaatagattg gcgtaacatc gctcatcatc
    30841 atcaggtggg tcagcgattt gtggcagtta cggtcaatca gaatggtgct gcctgctgga
    30901 gcagagtaca taccaacaat tttgttcgca gtggaagtac cgttggtcac catgtagctg
    30961 cggtctgcgt taaagacgcg agcgatatac tgttctgctt ctttgtgtgg accactgtga
    31021 tccagcagag aacccagttc agatactgaa atggaaatat cagatttcat ggtattcgga
    31081 ccaaagaaat catagaacag gctacctacc gggcttttct ggaatgcagt accgcccatg
    31141 tgaccaggag tacagaaagt atatttacct tcacgaacat atttaaacag tgctttagtc
    31201 agcggaggca gaatagtgtt gatatattcg tcagtggtct gcttgatctt attagcaata
    31261 tcttcagcag cacccagcgc atattcaaag aagctaatct gtaaacgcag gtcattcagg
    31321 cttacatcga gagtggaata cgtattagcg aacgcgtaca acggcaggtt ctcgttcatt
    31381 ttgctaattt cttcgcacag ctcgagatta tatttatccc agtcaaaaat aacgccgcac
    31441 agacgcgcat tgttttcgat cagttttaat aagtcgtcac ggtcgttcgg gtaaacaatc
    31501 tggaagttca gacgttcaag cgcgcgatga agttcacgga tgggttcttc tttaaaataa
    31561 acccccatgt gattcaatat tgcaataacg ttcatagtca tatctccagg taaaaaaggt
    31621 ccctcccaac acatgggaca aaatgaaagg aggagcctcg gaaaatactt ttaattaatg
    31681 tgcgttagac gcggtgtggt tatccattga gtggctctgg cgctcgtgca ttttgcgagc
    31741 gtagaacatc aggataatca ggctgacgat gaaggtacct gccagctcga aggagcttgc
    31801 gcccatcagc gcgatgaagc agaacacgca acccagtaca gagcagatca ggctgacaaa
    31861 gttgcggatg ttaacgcctt caaaacgaat caggtcaacg caagagtaga aatacggcag
    31921 catagtcagc agtactgcga taccggtcag ttcaccgaac aggtcagatg ctttaccacc
    31981 ggcagagttc atcagagtga taaggatcat cagggcagtc attttcactg cagccagcag
    32041 cagacctttt ttcggaatac cgttgctgtc gacttcacca taaactttcg ggaagttacc
    32101 gtcgttagcg gcacgtacac ctgcctggcc taccaacatc atccaggagc ccagagaagt
    32161 caggcacgca aaggcggtga atgcagaaac cagcggcgca gcccagttac cgaggatagt
    32221 tgaagcactg attgcaaacg gagcaccgga agccgccatt acagaagacg gatacatacc
    32281 ggaaagcacc tgagtcgcag cgatgtaaac aatacctgct aaaccagtac ccagcatggt
    32341 tgccagcgga acggtacgtt tcgggttttt aaccatacca gtacttacag ctgcggattc
    32401 aacacccacg aaggcccaca ggcagagcag aatactttta atgatcgcat gaccatcagt
    32461 ggtatccgca gtattccagt tagctgcata agttgccgca tcaaaccaat gccagccaac
    32521 aatagcagtc atcaccacag gaataagaac cagcaccaga ccaatagtgg ttaaacggct
    32581 tacccaagta ccgccgagca tatttacaaa ggtaaatacc cagacgatag caatacaggc
    32641 gatacccgcc ggaacaggat catttaatac tgggaagaag gtggaaagat aagatacagc
    32701 ggtaatacca atcgccaggt taccaatcca gttagcatgg taataaagaa cacctgtctg
    32761 aaaaccaaat gcaggggaaa tttctccggc ataagcaatt gggccacctt gttgcgggtt
    32821 ttttgttgcc agtcgggcat atacatacgc cagcgacatt gcaccaataa tagagataat
    32881 ccaaccccag atagcaatac caccgatact tgctaggttc gcaggtaata atgcaatacc
    32941 gctccccatc atattaccgg caacaacacc ggtacaggca aatagcccga tcttcttggc
    33001 agaactcatg ctcttctcct aatttcattt ttgaatttgg agtccgggtc atgatgtata
    33061 actatttcct gaccagacca aactggcgat aagattactc acgaaaaaag gattaatcct
    33121 aaagattagg tgaaataaca caaaagtttc tgtaagtgag aacttgaggt tttttattaa
    33181 cacatcagga tcgcaagttg atatcatgaa aagataaaca tttaatgttt acaatggatt
    33241 gcgtgacatt ctctggttaa atttatgtaa taaaaattat gcggcaaata aattgccgca
    33301 acatattata ccaacaggaa catacaaaaa ctcaacaaca aatatttccg agcataaatc
    33361 aacccggagt tacttattct gaagcaagaa atttgtcgag ataaggtaca acataaggaa
    33421 cagaagtctg gaatatacca ttttcaatcc agtaaagggt gtttgcccct gggcgtaaat
    33481 taaaggcggt gagatatgca tcagctgctt cccggttcat ccccttcatt tcataaacct
    33541 tgccaagcaa cacataattt agccaggaca tttcaagatc aatgccagta tttatcgcct
    33601 ggtaagactc atctgtttta ccttttacca gagcactgac cgcttttatt tgatatataa
    33661 tggacaggtt gttcaattcc ggcagtgtaa caatgttatc tatttctgtg ttcagtgctg
    33721 ctaattgttt ttcatctaaa ggatgttgag aatggcgcac gatatcaact aatgcttttt
    33781 ctgctctcgc gtaggtaaat tctggggatg attgaacaat ctcacctaat aattcactgg
    33841 cacggttcaa tgatttatca tcgccatgca gtaaataatc atgtgcctga taaaaattag
    33901 ttaataacgc accacgatgc ggcaaaattt tctggagcgt ctcctgcatt cgttgtggcc
    33961 acggttggtt taacgctttt gataaactct ccagtaaatc attttgaatc gccagctgat
    34021 taccgttagt gatgacataa cgtttatcca gcatggttga accatctgca ttgtctacca
    34081 attttatcga cataaagcat tgttgagcac ggtattggcg ctgattaaca aacgcaatag
    34141 ataatgtttt accggaactg ctcggttcat caatgttgta gttgattttg tcatgcacca
    34201 taaaggtgga gaaggtgtta agtgatgtcg ccaccaaatc acccacgcct atcgcgtaag
    34261 agagctgata cggggaactc cagctgttac aacttttatt taccatatta atgtcaatat
    34321 cgcgtggatt gagcaaaata cgcgatttgc tcataggaag acgtgtatca agacttgaaa
    34381 acgctaccag tgctacacag atacctaacg acaacaggaa aaaaaaccat acccaaaagg
    34441 tagtgaatcg tttgctttta actggggatt gttcaggtgg cgttgcggtg ttttgaatgt
    34501 taagactgtg ggagggagaa tctgtggcag gaaccgcctc tggtataggg ggaggcgaag
    34561 atagcattat ttcctctccc tcttcttcgc tgtaccagat aaccggcacc attaatttat
    34621 agccgcgctt tggtacagta gcgatataga caggactatc ttcatcatta tcttttaatg
    34681 acttacgtag ttctgagata ctctgcgtca caacgtgatt ggtgacaata cttctcttcc
    34741 agacattatc gataagttca tccctgctaa gtacttcgcc actgtgttga gcaaagaaaa
    34801 ccagaagatc gattaatctc ggctcaaggg taagttgacg cccattgcgg ctaatttggt
    34861 ttatggacgg agtaacaagc cattcgccaa cgcgaactac aggttgttgc ataatagaaa
    34921 ctcattcgaa aagggaatga tgcaatgata attgccacaa cctattttta ccatctatag
    34981 atgggtttat ttacatatta ttggtgaatg caagacgtta tttttaccag ccataaactt
    35041 cttgattaca tagtattacg aaaggatttt actgagaacc agaagtaata ttccttacca
    35101 tcaaaattca tcatctttgc caaagaaaaa tgttcagaaa ataatccatg gaaaattgtc
    35161 cggagcactt actattttaa tggattgtta gtctttgcat gagcaagcga actgatacat
    35221 ttctctttgt tctcattcag aaaatctcat cagtcgccgt tcagaccggt gttgtgcttt
    35281 atggatgcgt tacgctcctg atgacgtcat ttgacgttca acagcatcac ggggccgcac
    35341 gacatttcac gtcagttagt gctatagctc aggaacaaat tttcccgaat tgggatatgc
    35401 ccgcaaattg ctggtgatgt ggggagaatc tggttgagtt cggtagaatt gatttggagg
    35461 cagaacgctt aaatcgtggc gtcctgaaac gaaaaacgga cctccgtgga ggtccgttta
    35521 tatgaatttg gtgcccggac tcggaatcga accaaggaca cggggatttt caatcccctg
    35581 ctctaccgac tgagctatcc gggcaacggg gcgcattaaa ccgtaatctg cacatctcgt
    35641 caacctaatt tcagtaaaag cgattcaact gcttaagatt gcggcaaatc gcttcttttc
    35701 tgtgtttctg tcaggtcaat gcaccaccct ggcggcagcg ggcgaagcgc aggatatctt
    35761 ccgccagccg atgtgcagtg tcgacatccg cctggctacg attcaccagc attcggctta
    35821 aacagccttc cagcaccagt tccatctgct ttgctaccat cgccggatcg tcaacttcca
    35881 gtgtggttaa cagttcgtgg gtgaaatcgt aggccgcgct tttttgctga tcggccagtt
    35941 gatgaatagg gtggccagga tcgggataaa acgtacaggc agcgataaat agacagcccg
    36001 gatagcggtt gtttttaacg cactccgata acgcctgata acgtgccagc agcttttgtt
    36061 cggcggtttg cgtttcgtcc agcatcagct gacgacgcca gacatctatc tgttggctaa
    36121 gataacgcag cgcatcgtag aggattgcct ctttgtctgg ccagaagcgg cgtagctcgt
    36181 ccagtggata atccacacgt tcagcaacca tctccagcgt ggtgttggca atcccttgta
    36241 attctaataa tttcagggct tctcccagta catcttcacg ttgcacgcta ttttcctccg
    36301 tctttcccac tgcaagtgtc gttcacggtt ggcgatcgcg caaatgtgcg ctgaaggttt
    36361 cagcatccat aaagcccgtg acgcgtgctt gtggatgctc ctggccttgt ccgtcaaaaa
    36421 agagaattgt cggtaggcca aggacattaa gatgctttaa cagcgccaca tcttgtgcgt
    36481 cgttggccgt gacgttggcc tgaagtaaga ccgtgtctgc taacgctttt tgcacctgcg
    36541 ggtcgctgaa ggtgtatttc tcaaactctt tacaggcgac gcaccagtcg gcataaagat
    36601 ctaacatcac cggtttgcct ttggcttcaa cgagcgcctg atttaactca tctaccgttt
    36661 tgatttgtgt aaagttgaga tgcgtctgag tttgcgcggt atgcgtcgca ccaaatgccc
    36721 aatcctgaag tgggcgcacg ctaaccaatg ccgctgccag cagaataatt tgcacaatac
    36781 gcatccagcc gcgtttagcc tgtaggctgg tgataaaggc ccagccaaag aatgcgacac
    36841 ccagcgccga ccacaagcgt aatccccata catcaccaat cactcgctcc agcaggaaga
    36901 ccggcagtgc gaggatcaca aaaccaaacg cggttttgac ttgttccatc cacgggccgc
    36961 ttttcggcag caagcggtta ccaaagacgg taattagcat cagcggcagg cccatgccca
    37021 acgcatagag ataaagcgtg ccgccgccca gccacatgtt cccgctttgg gcgatataca
    37081 gcagaatcgc gctaagcggt gcggtggtgc atggtgaaca gatcagtccg gcaatcgccc
    37141 ccataacaaa cacaccgcca ggtgagccgc cctgttggcg attgctcatc aacgtgagac
    37201 gtgtttgcag cgaagagggg agttgcaggg taaacaagcc aaacattgac atcgccagca
    37261 aggtaaagac gatggcgagg ccaatgagca cgtatgggtg ctgtagcgcc gcctggaact
    37321 gtaaccctgc ggcggcaacc accagaccca gcgccgtgta ggtcagcgcc atcccctgca
    37381 cataaataaa ggtcagcaac aatgctctgg cagtggagag ccgctgttta ccacccagca
    37441 cgatgccaga aatcagtggg tacattggca gcacgcatgg cgtaaaggcg ataccaatac
    37501 cgatcaacaa cgcccagagc gcggaaaagg gcaattgcgc ggtgggctgc tcttgctgcg
    37561 gaacagacac aggctgtggc gctgcgttgt tggcgaccac ttcgcttaac ggaacggttt
    37621 tggtttctgg cggataacag aaaccggcat cagcacagcc ctggtaggtg acagttaacg
    37681 tcgctcccgc actcgcctgg ttgatggtga cgggaagcgt cagccgatcg cggtaaatct
    37741 cgcttttgcc gtaaaactca tcttcatgcc agacgccttg cggcagctgc acgtcggcaa
    37801 ttttcgcgtg ttccggcgta atgcggatct gtttacggta gaggtagtaa ccgtctttga
    37861 tctgccaggt cagattaagg tcatgttggt tttgctgaaa atcaaaagca aaggcttgat
    37921 ccgcggggac aaattgtgaa cgtcccggcg cgtcgaataa tccggcaaaa acggaagtgc
    37981 tgcaaagtag caggatcagc gtaaagatgc gttgagccat gagaggtaat ctgtgtctcc
    38041 gtgtgtaaca ggtaaaacca gaagttccgg ggtttgatat ggatgatgag acttcaggca
    38101 ttccagcagt gcctgctggt gagatacggt agtttttaaa atcatctgca cttcgtattc
    38161 ttgctccagc ttaccttccc agtaatagag agaggtagcg ccggggatca aggtcgcgca
    38221 ggccgccagt ttttccgcca gcactttggc ggctaaatcc tgggctgtcg cttcatctgg
    38281 tgccgtacat agcaccacga cagacgcggt attcgaactt ttttcatcaa gcataaacac
    38341 ctcgcaagaa cagatggaac cgcaagagag aggtcactat acaacggacg ggggaaggat
    38401 gttagtcggc gggaaagaaa gcggggcgtg aacgccccgc gattgatcat tacagcatga
    38461 agctacccag cacgaagccg aagcaaacgg ccagggcaac acccagagta cccgggatga
    38521 agaacggatg gttgaagacg aatttaccga tacgggtagt acccgtgtca tccatctgta
    38581 ccgcagcaac cagcgtcggg taggtcggca gaatgaacag accagacacc gcagcgaaag
    38641 aagcaacagc ggtcagcggt gaaacgttca gtgccagagc catcggcatc agtgcttttg
    38701 cggttgcagc ctgagagtac agcagagcag aagcaaagaa gaagatgacg gccagcagcc
    38761 acggatgacc ctgaatcact tcaccagcgg tatctttgat ccagtcgatg ttgttggaaa
    38821 cgaaagtatc gcccagccac gcaacaccca ggatacaaat acaggcgctc atacctgctt
    38881 tgaaggtgct ggagttgagg atgttgtcgg tatcgacttt acagataacg gtggtcagag
    38941 ttgcaacgct gagcatgatg atcaggattg cgttggtggt gttcatcagc ggtttttcaa
    39001 ccagacccat gcttgggctg ttgatgattg catagataac cacgccaact acgcccagca
    39061 ggaacagcca gacggacgtt tttgcaccgg atttgatttc aatctgcttt tcaccgcgca
    39121 gttcaaccag gccctcttcc agacgcttgc gataaatcgg atcgtcagag agtttggagt
    39181 tgaacagcat agtgaccagg aaggacatca ccagaaccgc cagcagggtg gacgggatga
    39241 ccacggagag cagatggagg tagctgatgc catgaccttc catcacggaa gacatgtaaa
    39301 ccactgccgc tgagattggc gatgcggtga tcgcaatctg cgcggatacc actgcagtag
    39361 acagcggacg gcaaggttta acgccttgtt ccttcgcaac ttcagcgata actggcagtg
    39421 tcgccagaga gatgttgcca gtaccagcaa agatagtcag gaaataggtc acgatcggtg
    39481 cgaggatcgt gatgtatttc gggttacggc gcagcagctt ttctgtctga tgaaccagat
    39541 agtccagacc gccagcaacc tgcatggcag aaatagcggc gataaccgcc atgataatgg
    39601 agatgacatc gaacgggatg ttaccgggtt taacgccaat agcggcaaga accagcaccc
    39661 ccaatccgcc tgcaaaacca atacctattc cccccaatct ggcgcccaag aagatcgcca
    39721 gcaaaactat gatgagttct acaactagca tattagcctt ccttgttttt taacaagttg
    39781 atattagatt gttattttta agttactgct cacaagaaaa aaggcacgtc atctgacgtg
    39841 ccttttttat ttgtactacc ctgtacgatt actgttcgct ttcatcagta tagcgttttg
    39901 ctttgtaagc cgggtgcatc agattctgta cggagaaaat atcgtcaagt tccgcttcag
    39961 tcaacagacc gcgttccaga acgacttcac gtacactctt accggtttcg gcacagattt
    40021 tacccacgat gtcaccgttg tggtgaccga tgaacgggtt caggtaagta acgataccga
    40081 tagagttgta aacgtaacct tcgcacactt ctttgttagc agtgatgccg ttaatgcatt
    40141 tttccagcag gttgtagcaa gcgttggtca gaatgtgaac ggattcgaac atggcctggc
    40201 caatgaccgg ctccataacg ttcaactgca gctgacctgc ttctgctgcc atggtaacag
    40261 tggtgtcgtt accgatgact ttgaagcata cctggttaac cacttccgga acaaccgggt
    40321 ttactttagc tggcatgatg gaagagcccg cctgcagttc cggcaggttg atctcgttca
    40381 ggccggcacg tgggcctgaa gagagcaagc gcaggtcgtt acagattttg gacatcttca
    40441 cagccaggcg tttcagcgcg ccgtgaacca taacataagc gccgcagtca gaggtcgctt
    40501 cgatcaggtc ttcagccggt acgcatggga agccagtaac ttcagccagt tttttcactg
    40561 ccagcggaga gtactctttc ggcgtgttca gaccagtacc gattgctgtt gcaccaaggt
    40621 taacttccag cagcagttca gcggtacgtt ggatgttttt cacttcttct ttcagcagga
    40681 tgctgaaagc gcggaattcc tgaccgaggg tcatcggtac tgcgtcctgc agctgggtac
    40741 gacccatttt caggatgtcc tggaattcga cagctttacg ttcaaagcct tcacgcagtt
    40801 ggttaatcgc atctaccagc ttaatcaggg aagagtaaac tgcgatacgg aaaccggtcg
    40861 ggtaggcgtc gttagtggac tgacatttgt taacatggtc gttcgggttc aggtactgat
    40921 attcaccttt ttggtgaccc atcagttcca gaccgatatt ggccagcact tcgttggtgt
    40981 tcatgtttac ggaagtacct gcgccgccct ggtagacgtc taccgggaac tgatccatgc
    41041 attttccgtt gttcaggact tcatcacatg cggcaatgat ggcattcgct acacttttag
    41101 gaatggtttg cagctctttg tttgccatag ctgcggcttt tttaaccatt accataccgc
    41161 gaacaaattc aggaatatca ctgattttgt tgttgctgat atagaagttt tcaatcgctc
    41221 tcagagtgtg aacaccatag taggcatcag ctggaacttc cctggtaccc aacagatctt
    41281 cttcgatacg aatgttgttt gacatgtgaa ccttcttttt caagctgcca atgatttgct
    41341 ttaaacacac agaatatatg tggtttcgaa tgtttttcga ccgacgatta tcccctgcat
    41401 cgaccgaata cccgagatca tatgctgctt gaggatttct accgtaatct ggatcacttt
    41461 aagtgtcggt ttttacccct taattattaa tttgtgaaat agatcaccgc tttgggatta
    41521 ctaccaaaaa tagttgcgca aacatcttga aattttgcta atgaccacaa tataagctaa
    41581 acgcgattcg caacccattc aggtagccgg ggttaaccgg ctgctattac aggagaaacc
    41641 tttgcgctgg ttacctttta ttgccatttt cctttatgtc tatattgaga tttcaatctt
    41701 tattcaggtt gcccatgtat tgggggtatt gctgaccctc gtgctggtta tattcacgtc
    41761 agttatcggt atgtcactgg tacgtaacca gggctttaag aatttcgtgc tgatgcagca
    41821 aaaaatggcg gcgggtgaaa acccagcggc ggagatgatt aaaagtgttt cgctgatcat
    41881 tgctggtttg ctgcttttat taccgggctt ttttaccgac ttcctcggtc ttctactttt
    41941 attgccgccg gtgcaaaagc atctgacagt gaagttgatg ccgcatttgc gcttttctcg
    42001 catgcctggc ggcggtttta gcgccgggac cggtggcggt aatacttttg atggtgagta
    42061 ccagcgaaag gatgatgagc gcgaccgcct tgatcataaa gacgatcgcc aggattaatg
    42121 tcgaaacgcc ggattatgtg gttatgccat tttccggcgt ttttcgtttt ggcagcaaca
    42181 gccataaccc cgccagcatg atcagcgcat agagactttt ccagccgacc attgccagta
    42241 acagaacgca taacagcccg ccaaccaccg ccagtagtcg ataacgtcct tgcaataatt
    42301 tacagcctgc cagcatgcat aacagataaa tcataataaa gatgccattg gcataaataa
    42361 taagagcgtc cagattgatc tctaaagcat gaatcaccaa agtgctcacc acacagcagc
    42421 cgagcaccgc attgagggca ttattcggga tatggcgaga agagaggcgt gccaggtagt
    42481 ggtcaggatt atgttgcgcc tgcgaccaga ccaggcgggc gaagctctgt atataaatgt
    42541 tgagactggc aaagcaggcc agatagccaa tcacgcaggc aatccataac gctcctacac
    42601 cgaacaactg cactacaatt tttggaagcg atgctgccgc cgccattttt tcaccatagg
    42661 cgtcgaagtg taagacgact accgtacagc cccagtagac taatcctgcc agcagcagac
    42721 caatcatcaa agcacgagga aaatcacgct ctggattttt aaattccgag gcgagatggg
    42781 caaatgcctc cagaccgaca aaacaccaga acatcactga taacgcagca aataacccgg
    42841 taagttcgat attaccaggt gccggaaagg ggatattcgc aggtttgata tctcccgccc
    42901 accagatagc gacaatcagc gcgacgataa gtccggcaat aacggtttgt agattagcac
    42961 tggaactggc accgcgagta ccgatatacc acaccagcgc cagcgtaccg agttctgcca
    43021 acaacagttg ccagctatgc cagccaaaca tcgcctggcc gaacccggcg gcaatttgta
    43081 gtgcggcagg caaacccacg ggaatgaccg ataaaaacag ccagccggtg actcgctcaa
    43141 gccgcgaacc aaacgccata ccgacgaagt gcgcgacgcc gcctgcgctg ggatagtggc
    43201 gacccagaat cgcaaacaca atcgcaatcg ggaacactaa gataatcaaa acgggccacg
    43261 cccacaggct gttattgccc gctaccagcg cagctaacgc aggaacggca aacacgccag
    43321 tgcctaataa tgacgtcgat agcaggccaa tgccctgggc cagccccagt tcttgtttga
    43381 gtccactcat gggttgatgt ccgattgcgc ccaaattttg ggcaactgcg tagattttcg
    43441 atggtagcac aatcagattc gcttatgacg gcgatgaaga aattgcgatg aaatgtgagg
    43501 tgaatcaggg ttttcacccg attttgtgct gatcagaatt ttttttcttt ttcccccttg
    43561 aaggggcgaa gcctcatccc catttctctg gtcaccagcc gggaaaccac gtaagctccg
    43621 gcgtcaccca taacagatac ggactttctc aaaggagagt tatcaatgaa tattcgtcca
    43681 ttgcatgatc gcgtgatcgt caagcgtaaa gaagttgaaa ctaaatctgc tggcggcatc
    43741 gttctgaccg gctctgcagc ggctaaatcc acccgcggcg aagtgctggc tgtcggcaat
    43801 ggccgtatcc ttgaaaatgg cgaagtgaag ccgctggatg tgaaagttgg cgacatcgtt
    43861 attttcaacg atggctacgg tgtgaaatct gagaagatcg acaatgaaga agtgttgatc
    43921 atgtccgaaa gcgacattct ggcaattgtt gaagcgtaat ccgcgcacga cactgaacat
    43981 acgaatttaa ggaataaaga taatggcagc taaagacgta aaattcggta acgacgctcg
    44041 tgtgaaaatg ctgcgcggcg taaacgtact ggcagatgca gtgaaagtta ccctcggtcc
    44101 aaaaggccgt aacgtagttc tggataaatc tttcggtgca ccgaccatca ccaaagatgg
    44161 tgtttccgtt gctcgtgaaa tcgaactgga agacaagttc gaaaatatgg gtgcgcagat
    44221 ggtgaaagaa gttgcctcta aagcaaacga cgctgcaggc gacggtacca ccactgcaac
    44281 cgtactggct caggctatca tcactgaagg tctgaaagct gttgctgcgg gcatgaaccc
    44341 gatggacctg aaacgtggta tcgacaaagc ggttaccgct gcagttgaag aactgaaagc
    44401 gctgtccgta ccatgctctg actctaaagc gattgctcag gttggtacca tctccgctaa
    44461 ctccgacgaa accgtaggta aactgatcgc tgaagcgatg gacaaagtcg gtaaagaagg
    44521 cgttatcacc gttgaagacg gtaccggtct gcaggacgaa ctggacgtgg ttgaaggtat
    44581 gcagttcgac cgtggctacc tgtctcctta cttcatcaac aagccggaaa ctggcgcagt
    44641 agaactggaa agcccgttca tcctgctggc tgacaagaaa atctccaaca tccgcgaaat
    44701 gctgccggtt ctggaagctg ttgccaaagc aggcaaaccg ctgctgatca tcgctgaaga
    44761 tgtagaaggc gaagcgctgg caactctggt tgttaacacc atgcgtggca tcgtgaaagt
    44821 cgctgcggtt aaagcaccgg gcttcggcga tcgtcgtaaa gctatgctgc aggatatcgc
    44881 aaccctgact ggcggtaccg tgatctctga agagatcggt atggagctgg aaaaagcaac
    44941 cctggaagac ctgggtcagg ctaaacgtgt tgtgatcaac aaagacacca ccactatcat
    45001 cgatggcgtg ggtgaagaag ctgcaatcca gggccgtgtt gctcagatcc gtcagcagat
    45061 tgaagaagca acttctgact acgaccgtga aaaactgcag gaacgcgtag cgaaactggc
    45121 aggcggcgtt gcagttatca aagtgggtgc tgctaccgaa gttgaaatga aagagaaaaa
    45181 agcacgcgtt gaagatgccc tgcacgcgac ccgtgctgcg gtagaagaag gcgtggttgc
    45241 tggtggtggt gttgcgctga tccgcgtagc gtctaaactg gctgacctgc gtggtcagaa
    45301 cgaagaccag aacgtgggta tcaaagttgc actgcgtgca atggaagctc cgctgcgtca
    45361 gatcgtattg aactgcggcg aagaaccgtc tgttgttgct aacaccgtta aaggcggcga
    45421 cggcaactac ggttacaacg cagcaaccga agaatacggc aacatgatcg acatgggtat
    45481 cctggatcca accaaagtaa ctcgttctgc tctgcagtac gcagcttctg tggctggcct
    45541 gatgatcacc accgaatgca tggttaccga cctgccgaaa aacgatgcag ctgacttagg
    45601 cgctgctggc ggtatgggcg gcatgggtgg catgggcggc atgatgtaat tgccctgcac
    45661 ctcgcagaaa taaacaaacc cccgggcaga aatgtctggg ggtttttctt ttggtcatct
    45721 ttctagtata agattcagac acggacgacg cgagtggcgt ccagctcatt gattatgggg
    45781 aataacatgc acgtaaaata cttagcaggg attgtcggtg ccgcgctact gatggcgggt
    45841 tgtagctcca gcaacgaatt gagtgctgcc ggtcagagtg tacgcattgt ggacgagcag
    45901 ccaggcgcag agtgccagct gattggtact gcgacaggta agcaaagcaa ctggctttcc
    45961 gggcaacacg gagaagaagg cggttctatg cgcggcgcag caaacgatct gcgcaaccag
    46021 gcggctgcaa tgggcggtaa cgtgatttat ggcatcagta gcccgtcgca gggaatgttg
    46081 tccagttttg tcccggcgga tagccagatt atcggtcagg tttataagtg cccgaactga
    46141 tgtgatccag aggctgggtg acaaacgtat aattgcctga tgcgcttcgc ttatcaggcc
    46201 tacataaggc attgcaactg attgaatgct tgagaatttg taggccggat aaggcgttta
    46261 cgccgcatcc ggcatgacca acgatcacgt tatcagtcat ttcaggctgg atggctccag
    46321 cctcgcatta gcaaagatga gattatttcg cctgtggtgc agttttgctg gtggattgaa
    46381 cacgtaagtg atgcagcgcg cgtaagcatt gatcctgggt tagcggttgg gcgttattcg
    46441 ccgctacggt gcgaacatag acctgacatg gcacacccgc gagttttttc agtcgtgggc
    46501 tgaaatcaag cattcggcga gtgatcgctt ctatttcttt acccggcgtt gcttcacgcg
    46561 ttttcaccac tgcgccgcta aattgttctt tgccactttc atctttaaag cggtaaagca
    46621 ccgccagata atggtcgaac aagttatgtt tccattccgg ttgggaatag gtgtcatatt
    46681 ccagattgcc attgtcctgg cagtcaacgt cgtataacgg caggaaatct aacagtgagg
    46741 taatacgtaa tgccagttca cgcatttccg cattattaat tgcatgaatg attgctcgcg
    46801 ccagcatttc aatctgcaac tcattgacga ctaactcaca tttgctaccg tcatgtagcg
    46861 ttaatacgaa ggtaagattt tcgccttgat tatcggtaag ttccagcgtg ttaacccgac
    46921 gattaatatc ggcattttta agctcatcaa ccagaatttc tgggatgttt tctgccattt
    46981 tcttaatgac tttatcgcga gcttgctcat actgaaggtg tgcagcagca tccagtttat
    47041 gcttttgatg cagacgactt tccagcgcaa tcagcaggtc gcgcagttcc atgacagaca
    47101 taaagaacaa cgattcttta ttgcgaggtt ctttaatttt cagcgccagt gcaatgaaat
    47161 tattactctt gcgaataaca ccggtattaa cacccttgat gcttatggcc atgtaggttc
    47221 tccctaacca tttctcaatt aaataattaa ttttaattta taag
//
LOCUS       DAPOAV010000029        46211 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.029, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000029 DAPOAV010000000
VERSION     DAPOAV010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 46211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46211
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.029"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            139..834
                     /gene="araD"
                     /locus_tag="RN951_001880"
     CDS             139..834
                     /gene="araD"
                     /locus_tag="RN951_001880"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDX2526887.1"
                     /translation="MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVERERGVFVIKPS
                     GVDYSVMTADDMVVVSIETGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHAT
                     IWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDA
                     AQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKH
                     YLRKHGAKAYYGQ"
     gene            909..3260
                     /gene="polB"
                     /locus_tag="RN951_001881"
     CDS             909..3260
                     /gene="polB"
                     /locus_tag="RN951_001881"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase II"
                     /protein_id="HDX2526888.1"
                     /translation="MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAF
                     IPADQVPRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVT
                     VYEADVRPPERYLMERFITSPVWVEGDMHNGTIVNARLKPHPDYRPPLKWVSIDIETT
                     RHGELYCIGLEGCGQRIVYMLGPENGDASSLDFELEYVASRPQLLEKLNTWFANYDPD
                     VIIGWNVVQFDLRMLQKHAERYRLPLRLGRDNSELEWREHGFKNGVFFAQAKGRLIID
                     GIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLK
                     DCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLG
                     EVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHS
                     TEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTAC
                     RFFDPRLASSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKGAHSEEEAAKIG
                     RALVQHVNAWWAETLQKQRLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEG
                     DKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYVRETIDKLMAGELDARL
                     VYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQNRGTIKYVWTTNGPEPL
                     DYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF"
     gene            3425..6331
                     /gene="rapA"
                     /locus_tag="RN951_001882"
     CDS             3425..6331
                     /gene="rapA"
                     /locus_tag="RN951_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001117023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-associated protein RapA"
                     /protein_id="HDX2526889.1"
                     /translation="MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYA
                     RSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFL
                     DSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLN
                     IAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVE
                     MLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDL
                     LVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPN
                     RFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSD
                     SEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKV
                     SGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLV
                     ICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIG
                     SEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRW
                     YHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLE
                     QGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVL
                     TPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGS
                     STISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQV
                     EFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKL
                     SAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ"
     gene            6343..7002
                     /gene="rluA"
                     /locus_tag="RN951_001883"
     CDS             6343..7002
                     /gene="rluA"
                     /locus_tag="RN951_001883"
                     /EC_number="5.4.99.28"
                     /EC_number="5.4.99.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA pseudouridine(32) synthase/23S
                     rRNA pseudouridine(746) synthase RluA"
                     /protein_id="HDX2526890.1"
                     /translation="MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKD
                     SVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWG
                     HPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGR
                     SHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAD
                     F"
     gene            7215..7393
                     /locus_tag="RN951_001884"
                     /pseudo
     CDS             7215..7393
                     /locus_tag="RN951_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244358.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            complement(7410..7568)
                     /locus_tag="RN951_001885"
     CDS             complement(7410..7568)
                     /locus_tag="RN951_001885"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526891.1"
                     /translation="MNGATSLYDEVIIINKIPPKKIDTKGVATEEVATKKVLLNKLLT
                     TQLLNEPE"
     gene            complement(7565..8230)
                     /locus_tag="RN951_001886"
                     /pseudo
     CDS             complement(7565..8230)
                     /locus_tag="RN951_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518734.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8525..9340)
                     /gene="djlA"
                     /locus_tag="RN951_001887"
     CDS             complement(8525..9340)
                     /gene="djlA"
                     /locus_tag="RN951_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone DjlA"
                     /protein_id="HDX2526892.1"
                     /translation="MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWF
                     ANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFR
                     VGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEE
                     LGISRAQFDQFLRMMQGGAQFGGGYQQQTGGGNWQQAQRGPTLEDACNVLGVKPTDDA
                     TTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK"
     gene            9595..11949
                     /gene="lptD"
                     /locus_tag="RN951_001888"
     CDS             9595..11949
                     /gene="lptD"
                     /locus_tag="RN951_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly protein LptD"
                     /protein_id="HDX2526893.1"
                     /translation="MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQ
                     GDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVR
                     TVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGEN
                     RYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQL
                     PVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEF
                     RYLSQAGAGLMELDYLPSDKVYEDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKV
                     SDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEP
                     QLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTE
                     AKLLATHYQQTNLDWYNSRNTTKLDESVNRVMPQFKVDGKMVFERDMEMLAPGYTQTL
                     EPRAQYLYVPYRDQSDIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRI
                     YDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISERWGLRG
                     GIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGI
                     SQIGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWD
                     NDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL"
     gene            12002..13288
                     /gene="surA"
                     /locus_tag="RN951_001889"
     CDS             12002..13288
                     /gene="surA"
                     /locus_tag="RN951_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase SurA"
                     /protein_id="HDX2526894.1"
                     /translation="MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDG
                     LMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIAN
                     IAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESL
                     AQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIA
                     HSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGE
                     SKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGS
                     ANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAA
                     QKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN"
     gene            13288..14277
                     /gene="pdxA"
                     /locus_tag="RN951_001890"
     CDS             13288..14277
                     /gene="pdxA"
                     /locus_tag="RN951_001890"
                     /EC_number="1.1.1.262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="HDX2526895.1"
                     /translation="MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLT
                     NRAAMLGLPLTLRPYSPNSPAQPQTAGTLTLLPVALRAPVTAGQLAVENGHYVVETLA
                     RACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRV
                     ALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHM
                     GTEEIDTIIPVLNELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQ
                     GFGRGVNITLGLPFIRTSVDHGTALELAGRGKADVGSFITALNLAIKMIVNTQ"
     gene            14274..15095
                     /gene="rsmA"
                     /locus_tag="RN951_001891"
     CDS             14274..15095
                     /gene="rsmA"
                     /locus_tag="RN951_001891"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HDX2526896.1"
                     /translation="MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEI
                     GPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAE
                     KMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRL
                     SVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAF
                     NQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES"
     gene            15098..15475
                     /gene="apaG"
                     /locus_tag="RN951_001892"
     CDS             15098..15475
                     /gene="apaG"
                     /locus_tag="RN951_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Co2+/Mg2+ efflux protein ApaG"
                     /protein_id="HDX2526897.1"
                     /translation="MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQ
                     LLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMI
                     DENGVPFSIDIPVFRLAVPTLIH"
     gene            15482..16324
                     /gene="apaH"
                     /locus_tag="RN951_001893"
     CDS             15482..16324
                     /gene="apaH"
                     /locus_tag="RN951_001893"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     ApaH"
                     /protein_id="HDX2526898.1"
                     /translation="MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPG
                     SLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWL
                     RRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMP
                     NNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVA
                     EEYSIAFGHWASLEGKGTPEGIYALDTGCCWGGTLTCLRWEDKQYFVQPSNRHKDLGE
                     AAAS"
     gene            complement(16402..16881)
                     /gene="folA"
                     /locus_tag="RN951_001894"
     CDS             complement(16402..16881)
                     /gene="folA"
                     /locus_tag="RN951_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 3 dihydrofolate reductase"
                     /protein_id="HDX2526899.1"
                     /translation="MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGR
                     HTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQ
                     FLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR"
     gene            complement(17072..18934)
                     /gene="kefC"
                     /locus_tag="RN951_001895"
     CDS             complement(17072..18934)
                     /gene="kefC"
                     /locus_tag="RN951_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefC"
                     /protein_id="HDX2526900.1"
                     /translation="MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPW
                     GLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGCGALQMVICGGLLG
                     LFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAI
                     PLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREV
                     FSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLF
                     FIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQ
                     GSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREA
                     DEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDA
                     TRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQ
                     AGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTK
                     ARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS"
     gene            complement(18927..19457)
                     /gene="kefF"
                     /locus_tag="RN951_001896"
     CDS             complement(18927..19457)
                     /gene="kefF"
                     /locus_tag="RN951_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     oxidoreductase KefF"
                     /protein_id="HDX2526901.1"
                     /translation="MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNI
                     DIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLW
                     AVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQA
                     RHYKQRLLEWQEAHHG"
     gene            complement(19565..20896)
                     /locus_tag="RN951_001897"
     CDS             complement(19565..20896)
                     /locus_tag="RN951_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2526902.1"
                     /translation="MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQL
                     TPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMF
                     VSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
                     VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFG
                     EPVAFDEEQPQQTRFRDLFNRRHFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLG
                     VGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGI
                     WLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPI
                     FINNYGISNTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG"
     gene            complement(20953..21240)
                     /gene="fixX"
                     /locus_tag="RN951_001898"
     CDS             complement(20953..21240)
                     /gene="fixX"
                     /locus_tag="RN951_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like protein FixX"
                     /protein_id="HDX2526903.1"
                     /translation="MTSPVNVDVKLGVNKFNVDEEHPHIVVKADADKQALELLVKACP
                     AGLYKKQDDGSVRFDYAGCLECGTCRILGLGSALEQWEYPRGTFGVEFRYG"
     gene            complement(21237..22523)
                     /locus_tag="RN951_001899"
     CDS             complement(21237..22523)
                     /locus_tag="RN951_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDX2526904.1"
                     /translation="MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKN
                     VTGGRLYAHSLEHIIPGFADSAPVERLITHEKLAFMTEKSAMTMDYCNGDETSPSQRS
                     YSVLRSKFDAWLMEQAEEAGAQLITGIRVDNLVQRDGKVVGVEADGDVIEAKTVILAD
                     GVNSILAEKLGMAKRVKPTDVAVGVKELIELPKSVIEDRFQLQGNQGAACLFAGSPTD
                     GLMGGGFLYTNENTLSLGLVCGLHHLHDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEY
                     SAHVVPEAGINMLPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAIAAGEAAAKTVLSA
                     MKSDDFSKQKLAEYRQHLESGPLRDMRMYQKLPAFLDNPRMFSGYPELAVGVARDLFT
                     IDGSAPELMRKKILRHGKKVGFINLIKDGMKGVTVL"
     gene            complement(22574..23515)
                     /locus_tag="RN951_001900"
     CDS             complement(22574..23515)
                     /locus_tag="RN951_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDX2526905.1"
                     /translation="MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGAQA
                     IQLGANHVWKLNGKPDDRMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYR
                     LKAAVSNDASTVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDAS
                     RTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLC
                     KAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQT
                     IFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR"
     gene            complement(23530..24300)
                     /locus_tag="RN951_001901"
     CDS             complement(23530..24300)
                     /locus_tag="RN951_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein FixA"
                     /protein_id="HDX2526906.1"
                     /translation="MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEA
                     ACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTAS
                     ALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVE
                     RELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAA
                     WSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI"
     gene            24773..26287
                     /gene="caiT"
                     /locus_tag="RN951_001902"
     CDS             24773..26287
                     /gene="caiT"
                     /locus_tag="RN951_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine/gamma-butyrobetaine antiport BCCT
                     transporter"
                     /protein_id="HDX2526907.1"
                     /translation="MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVF
                     SYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSA
                     AVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYF
                     FFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTEC
                     MQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIV
                     SGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIF
                     LARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVAR
                     AIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRI
                     GWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD"
     gene            26318..27460
                     /gene="caiA"
                     /locus_tag="RN951_001903"
     CDS             26318..27460
                     /gene="caiA"
                     /locus_tag="RN951_001903"
                     /EC_number="1.3.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA dehydrogenase"
                     /protein_id="HDX2526908.1"
                     /translation="MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVK
                     ALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGT
                     QEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSA
                     YTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELD
                     EKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRF
                     QLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQ
                     VLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR"
     gene            27578..28795
                     /gene="caiB"
                     /locus_tag="RN951_001904"
     CDS             27578..28795
                     /gene="caiB"
                     /locus_tag="RN951_001904"
                     /EC_number="2.8.3.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine CoA-transferase"
                     /protein_id="HDX2526909.1"
                     /translation="MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIE
                     NVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFA
                     RRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQP
                     MPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNG
                     GEMCPRMTKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPE
                     GTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQY
                     VARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDI
                     QELVSKGLAKVED"
     gene            28869..30422
                     /gene="caiC"
                     /locus_tag="RN951_001905"
                     /pseudo
     CDS             28869..30422
                     /gene="caiC"
                     /locus_tag="RN951_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308067.2"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetaine/carnitine-CoA ligase"
     gene            30531..31316
                     /gene="caiD"
                     /locus_tag="RN951_001906"
     CDS             30531..31316
                     /gene="caiD"
                     /locus_tag="RN951_001906"
                     /EC_number="4.2.1.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA hydratase"
                     /protein_id="HDX2526910.1"
                     /translation="MSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDD
                     PQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVN
                     GYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVM
                     TGRRMGAEEALRWGIVNRVVNQAELMDNARELAQQLVNSAPLAIAALKEIYRTTSEMP
                     VEEAYRYIRSGVLKHYPSVLHSEDAIEGPLAFAEKRDPVWKGR"
     gene            31322..31912
                     /gene="caiE"
                     /locus_tag="RN951_001907"
     CDS             31322..31912
                     /gene="caiE"
                     /locus_tag="RN951_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308065.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine operon protein CaiE"
                     /protein_id="HDX2526911.1"
                     /translation="MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLR
                     GDYGRLIVQAGANIQDGCIMHGYCNTDTIVGENGHIGHGAILHGCVIGRDALVGMNSV
                     IMDGAVIGEESIVAAMSFIKAGFRGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQ
                     DLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR"
     gene            complement(32031..32426)
                     /gene="caiF"
                     /locus_tag="RN951_001908"
     CDS             complement(32031..32426)
                     /gene="caiF"
                     /locus_tag="RN951_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414576.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine metabolism transcriptional regulator
                     CaiF"
                     /protein_id="HDX2526912.1"
                     /translation="MCEGYVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNT
                     LTYILSEVTEISCEVKMIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSREKLVGVR
                     KTPRIPAVPLTELNREQKWQMMLSKSMRR"
     gene            complement(32687..35905)
                     /gene="carB"
                     /locus_tag="RN951_001909"
     CDS             complement(32687..35905)
                     /gene="carB"
                     /locus_tag="RN951_001909"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDX2526913.1"
                     /translation="MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRV
                     ILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALEL
                     ERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHSMEEALAVAA
                     EVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEM
                     EVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIG
                     VETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDE
                     LMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQ
                     ESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGAERIWYIADAFRAGLSVD
                     GVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLNADFLRQLKRKGFADARLAKLAGV
                     REAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECESNPSDRDKIMVLGG
                     GPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLED
                     VLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAVD
                     RLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQTA
                     VSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPAY
                     TLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKAT
                     GVPLAKVAARVMAGKTLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRSTG
                     EVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELDA
                     THGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIRR
                     SALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK"
     gene            complement(35923..37071)
                     /gene="carA"
                     /locus_tag="RN951_001910"
     CDS             complement(35923..37071)
                     /gene="carA"
                     /locus_tag="RN951_001910"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDX2526914.1"
                     /translation="MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILT
                     DPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYL
                     KRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAK
                     EVTTAEPYSWTQGSWTLTGGLPEAKKEDELPFHVVAYDFGAKRNILRMLVDRGCRLTI
                     VPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLA
                     LASGAKTIKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEATLPANLRVTHKSLFD
                     GTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIALIEQYRKTAK"
     gene            complement(37527..38348)
                     /gene="dapB"
                     /locus_tag="RN951_001911"
     CDS             complement(37527..38348)
                     /gene="dapB"
                     /locus_tag="RN951_001911"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDX2526915.1"
                     /translation="MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSL
                     LGSDAGELAGAGKTGVTVQSSLDAVKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIG
                     TTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHH
                     RHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGSIGFATVRAGDIVG
                     EHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKESGLFDMRDVLDLNNL"
     gene            complement(38515..39429)
                     /gene="rihC"
                     /locus_tag="RN951_001912"
     CDS             complement(38515..39429)
                     /gene="rihC"
                     /locus_tag="RN951_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside hydrolase RihC"
                     /protein_id="HDX2526916.1"
                     /translation="MRLPIFLDTDPGIDDAVAIAAAIFAPELDLQLMTTVAGNVSVEK
                     TTRNALQLLHFWNAEIPLAQGAAVPLVRAPRNAASVHGESGMAGYDFVEHNRSPLDKP
                     AFLAIRDALLRAPEPVTLVAIGPLTNIALLLSQCPECKPHIRRLVIMGGSAGRGNCTP
                     NAEFNIAADPEAAACVFRSGIEIVMCGLDVTNQAILTPDYLATLPELNRTGKMLHALF
                     SHYRSGSMQSGLRMHDLCAIAWLVRPDLFTLKPCFVAVETQGEFTSGTTVVDIDGCLG
                     KPANVKVALDLNVKGFQQWVAEVLALVP"
     gene            complement(39495..40445)
                     /gene="ispH"
                     /locus_tag="RN951_001913"
                     /gene_synonym="lytB"
     CDS             complement(39495..40445)
                     /gene="ispH"
                     /locus_tag="RN951_001913"
                     /gene_synonym="lytB"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HDX2526917.1"
                     /translation="MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRY
                     VVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKV
                     HMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEK
                     LSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVL
                     VVGSKNSSNSNRLAELAQRMGKRAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQ
                     NVVARLQQLGGGEAIPLEGREENIVFEVPKELRVDIREVD"
     gene            complement(40447..40896)
                     /gene="fkpB"
                     /locus_tag="RN951_001914"
     CDS             complement(40447..40896)
                     /gene="fkpB"
                     /locus_tag="RN951_001914"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDX2526918.1"
                     /translation="MSESVQSNSAVLVHFTLKLDDGTTAESTRNNGKPALFRLGDASL
                     SEGLEQHLLGLKVGDKTTFSLEPDAAFGVPSPDLIQYFSRREFMDAGEPEIGAIMLFT
                     AMDGSEMPGVIREINGDSITVDFNHPLAGQTVHFDIEVLEIDPALEA"
     gene            complement(41004..41498)
                     /gene="lspA"
                     /locus_tag="RN951_001915"
     CDS             complement(41004..41498)
                     /gene="lspA"
                     /locus_tag="RN951_001915"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDX2526919.1"
                     /translation="MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFP
                     SLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYA
                     LIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSK
                     AKKQ"
     gene            complement(41498..44314)
                     /gene="ileS"
                     /locus_tag="RN951_001916"
     CDS             complement(41498..44314)
                     /gene="ileS"
                     /locus_tag="RN951_001916"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HDX2526920.1"
                     /translation="MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAA
                     KKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPI
                     ELKVEQEYGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFK
                     TEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAVD
                     QDALKAKFGVSNVNGPISLVIWTTTPWTLPANRAISIAPDFDYALVQIDGQAVILAKD
                     LVESVMQRIGVTDYTILGTVKGAELELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHT
                     APGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVVALLQEKGA
                     LLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQA
                     RIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHPRTLELMEEVAKRVEVDGIQAW
                     WDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVDVRPEFAGHAADMYLEGSDQH
                     RGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADI
                     LRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMV
                     VLDRWAVGCAKAAQEDILKAYEAYDFHEVVQRQMRFCSVEMGSFYLDIIKDRQYTAKA
                     DSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTGEWYEGLFGL
                     ADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYAEPELAAKLTALG
                     DELRFVLLTSGATVADYNDAPADAQQSEVLKGLKVALSKAEGEKCPRCWHYTQDVGKV
                     AEHAEICDRCVSNVAGDGEKRKFA"
     gene            complement(44357..45298)
                     /gene="ribF"
                     /locus_tag="RN951_001917"
     CDS             complement(44357..45298)
                     /gene="ribF"
                     /locus_tag="RN951_001917"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HDX2526921.1"
                     /translation="MKLIRGIHNLSQAPQEGCVLTIGNFDGVHRGHRALLQGLQEEGR
                     KRNLPVMVMLFEPQPLELFATDKAPARLTRLREKLRYLAECGVDYVLCVRFDRRFAAL
                     TAQNFISDLLVKHLRVKFLAVGDDFRFGAGREGDFLLLQKAGMEYGFDITSTQTFCEG
                     GVRISSTAVRQALADDNLALAESLLGHPFAISGRVVHGDELGRTIGFPTANVPLRRQV
                     SPVKGVYAVEVLDLGEKPLPGVANIGTRPTVAGIRQQLEVHLLDVAMDLYGRHIQVVL
                     RKKIRNEQRFASLDELKAQIARDELTAREFFGLTKPA"
     gene            complement(45306..45524)
                     /locus_tag="RN951_001918"
     CDS             complement(45306..45524)
                     /locus_tag="RN951_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2575 family protein"
                     /protein_id="HDX2526922.1"
                     /translation="MCRHSLRSDGAGFYQLAGCEYSFSAIKIAAGGQFLPVICAMAMK
                     SHFFLISVLNRRLTLTAVQGILGRFSLF"
     gene            45627..45890
                     /gene="rpsT"
                     /locus_tag="RN951_001919"
     CDS             45627..45890
                     /gene="rpsT"
                     /locus_tag="RN951_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006117633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HDX2526923.1"
                     /translation="MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDK
                     AAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA"
BASE COUNT        11096 a        12530 c        11879 g        10706 t
ORIGIN      
        1 ctgcgatttt gtaggccgga taagcaaagc gcatccggca ttcaacgcct gatgcgacgc
       61 tggcgcgtct tatcaggcct acacgctgcg attttgtagg ccggataagc aaagcgcatc
      121 cggcacgaag gagtcaacat gttagaagat ctcaaacgcc aggtattaga agccaacctg
      181 gcgctgccaa aacacaacct ggtcacgctc acatggggca acgtcagcgc cgttgagcgc
      241 gagcgcggcg tctttgtgat caaaccttcc ggcgtcgatt acagcgtcat gaccgctgac
      301 gatatggtcg tggttagcat cgaaaccggt gaagtggttg aaggtacgaa aaagccctcc
      361 tccgacacgc caactcaccg gctgctctat caggcattcc cctccattgg cggcattgtg
      421 catacgcact cgcgccacgc caccatctgg gcgcaggcgg gtcagtcgat tccagcaacc
      481 ggcaccaccc acgccgacta tttctacggc accattccct gcacccgcaa aatgaccgac
      541 gcagaaatca acggcgaata tgagtgggaa accggtaacg tcatcgtaga aacctttgaa
      601 aaacagggta tcgatgcagc gcaaatgccc ggcgttctgg tccattccca cggcccgttt
      661 gcatggggca aaaatgccga agatgcggtg cataacgcca tcgtgctgga agaggtcgct
      721 tatatgggga tattctgccg tcagttagcg ccgcagttac cggatatgca gcaaacgctg
      781 ctggataaac actatctgcg taagcatggc gcgaaggcat attacgggca gtaatgactg
      841 tataaaacca cagccaatca aacgaaacca ggctatactc aagcctggtt ttttgatgga
      901 ttttcagcgt ggcgcaggca ggttttatct taacccgaca ctggcgggac accccgcaag
      961 ggacagaagt ctccttctgg ctggcgacgg acaacgggcc gttgcaggtt acgcttgcac
     1021 cgcaagagtc cgtggcgttt attcccgccg atcaggttcc ccgcgctcag catattttgc
     1081 agggtgaaca aggctttcgc ctgacaccgc tggcgttaaa ggattttcac cgccagccgg
     1141 tgtatggcct ttactgtcgc gcccatcgcc aattgatgaa ttacgaaaag cgcctgcgtg
     1201 aaggtggcgt taccgtctac gaggccgatg tgcgtccgcc agaacgctat ctgatggagc
     1261 ggtttatcac ctcaccggtg tgggtcgagg gtgatatgca caatggcact atcgttaatg
     1321 cccgtctgaa accgcatccc gactatcgtc cgccgctcaa gtgggtttct atagatattg
     1381 aaaccacccg ccacggtgag ctgtactgca tcggcctgga aggctgcggg cagcgcatcg
     1441 tttatatgct ggggccggag aatggcgacg cctcctcgct tgatttcgaa ctggaatacg
     1501 tcgccagccg cccgcagttg ctggaaaaac tcaacacctg gtttgccaac tacgatcctg
     1561 atgtgatcat cggttggaac gtggtgcagt tcgatctgcg aatgctgcaa aaacatgccg
     1621 agcgttaccg tcttccgctg cgtcttgggc gcgataatag cgagctggag tggcgcgagc
     1681 acggctttaa aaacggcgtc ttttttgccc aggctaaagg tcggctaatt atcgacggta
     1741 tcgaggcgct gaaatccgcg ttctggaatt tctcttcatt ctcgctggaa actgtcgctc
     1801 aggagctatt aggcgaagga aaatctatcg ataacccgtg ggatcgaatg gacgaaattg
     1861 accgccgttt cgccgaagat aaacctgcgc tggcaactta taacctgaaa gattgcgagc
     1921 tggtgacgca gatcttccac aaaactgaaa tcatgccatt tttactcgaa cgggcaacgg
     1981 tgaacggcct gccggtggac cgacacggcg gttcggtggc ggcatttggt catctctatt
     2041 ttccgcgaat gcatcgcgct ggttatgtcg cgcctaatct cggcgaagtg ccgccgcacg
     2101 ccagccctgg cggctacgtg atggattcac ggccagggct ttatgattca gtgctggtgc
     2161 tggactataa aagcctgtac ccgtcgatca tccgcacctt tctgattgat cccgtcgggc
     2221 tggtggaagg catggcgcag cctgatccag agcacagtac cgaaggtttt ctcgatgcct
     2281 ggttctcgcg agaaaaacat tgcctgccgg agattgtgac taacatctgg cacgggcgcg
     2341 atgaagccaa acgccagggt aacaaaccgc tgtcgcaggc gctgaaaatc atcatgaatg
     2401 ccttttatgg cgtgctcggc accaccgcct gccgcttctt cgatccgcgg ctggcatcgt
     2461 cgatcaccat gcgtggtcat cagatcatgc ggcaaaccaa agcgttgatt gaagcacagg
     2521 gctacgacgt tatctacggc gataccgact caacgtttgt ctggctgaaa ggcgcacatt
     2581 cggaagaaga agcggcgaaa atcggtcgtg cactggtgca gcacgttaac gcctggtggg
     2641 cggaaacgct gcaaaaacaa cggctgacca gcgcattaga actggagtat gaaacccatt
     2701 tctgccgttt tctgatgcca accattcgcg gagccgatac cggcagtaaa aagcgttatg
     2761 ccggactgat tcaggagggc gacaagcagc ggatggtgtt taaagggctg gaaaccgtgc
     2821 gcaccgactg gacgccgctg gcccagcagt ttcagcagga gctatacctg cgcatcttcc
     2881 gcaacgagcc atatcaggaa tatgtacgcg aaaccatcga caaactgatg gcgggtgaac
     2941 tggatgcgcg actggtttac cgtaaacgcc ttcgccgtcc gctgagcgag tatcagcgta
     3001 atgtgccgcc tcatgtacgc gccgctcgcc ttgccgatga agaaaaccaa aagcgtggtc
     3061 gccccttgca atatcagaat cgcggcacca ttaagtacgt atggaccacc aacggcccgg
     3121 agccgctgga ctaccaacgt tcaccactgg attacgaaca ctatctgacc cgccagctac
     3181 aacccgtggc ggagggaata ctccctttta ttgaggataa ttttgctaca cttatgaccg
     3241 ggcaacttgg gctattttga gcaaaaaaaa gagttcgcca gataccattt tgatgcgtga
     3301 cgaatgcttt gccatccagt accatagcgc cctttccatt cctggacctg aataacacca
     3361 ctacctcata agcacggtag cgggtggtta ttgcctgcaa ttaaagatat agagccgaac
     3421 acatatgcct tttacacttg gtcaacgctg gatcagcgat acagaaagcg aattgggact
     3481 tggaaccgtt gtcgcggtgg atgcgcgaac tgtcacttta cttttcccat ctactggtga
     3541 aaaccgtctg tacgcacgca gtgattcccc cgtgacccgc gtgatgttca accctggtga
     3601 taccattacc agccatgacg gctggcagat gcaagtcgaa gaagtaaaag aagaaaatgg
     3661 cttgctgacc tatatcggta ctcgcctgga tactgaagag tccggcgtag ccctgcgtga
     3721 agttttcctt gatagcaaac tggtgttcag caaaccgcag gaccgtctgt ttgccgggca
     3781 gattgaccgt atggaccgct ttgcgctgcg ttatcgcgcg cgtaaatatt ccagcgaaca
     3841 gttccgtatg ccgtacagcg gcctgcgcgg tcagcgtacc agcctgatcc cgcatcagct
     3901 caacatcgct catgatgttg gtcgccgcca cgcgccgcgc gtcctgctgg ctgacgaagt
     3961 gggtttaggg aaaaccattg aagccgggat gatcctgcat cagcaactgc tctctggcgc
     4021 tgctgaacgt gtgctaatta tcgtcccgga aaccttacag catcagtggc tggtagaaat
     4081 gctgcgccgt ttcaacctgc gctttgcgct atttgatgat gagcgttatg ccgaagctca
     4141 gcacgatgct tacaacccgt ttgacaccga acagctggtg atttgctcgc tggattttgc
     4201 ccgtcgtagc aaacagcgcc tggaacatct ctgtgaagcc gaatgggacc tgctggtggt
     4261 cgatgaagcg catcacctgg tgtggagcga agatgcgcca agccgtgaat atcaggccat
     4321 tgaacaactg gcagagcacg tgccgggcgt tctgctgctg accgcgaccc cggaacagct
     4381 ggggatggaa agccacttcg cccgtctgcg tctgctggac ccgaaccgtt tccacgattt
     4441 tgcgcagttc gttgaagagc agaaaaatta tcgtccggtt gcggacgccg ttgccatgct
     4501 gctggcaggt aacaaactga gcaatgacga actgaacatg ctcggcgaga tgatcggcga
     4561 gcaggatatc gagccgctgt tgcaggcagc aaacagcgac agcgaagatg cccagagcgc
     4621 ccgtcaggag ctggtttcga tgctgatgga tcgccacggc accagccgcg tgctgttccg
     4681 taacacgcgt aacggtgtga aaggattccc gaaacgcgag ctgcacacca ttaagctgcc
     4741 gctaccgacg cagtatcaga cggctattaa agtctccggc attatgggcg cacgtaaaag
     4801 tgcggaagat cgtgctcgcg atatgctcta cccggagcgt atttatcagg aatttgaagg
     4861 tgataacgcc acctggtgga acttcgatcc gcgcgttgag tggctgatgg gctacctgac
     4921 cagccatcgc tctcagaaag tgctggtgat ctgcgccaaa gctgccactg cgctgcaact
     4981 ggagcaggta ctgcgcgaac gtgaaggtat tcgcgctgcg gtgttccacg aaggtatgtc
     5041 gattatcgaa cgtgaccgcg ctgccgcctg gtttgccgaa gaagacaccg gcgcacaggt
     5101 actgctgtgc tcagaaatcg gttctgaagg acgtaacttc cagttcgcca gccacatggt
     5161 gatgtttgac ctgccattca acccggatct actggagcag cgtattggtc gtctggatcg
     5221 tatcggccag gcgcacgata ttcagatcca tgtgccttat ctggagaaaa ccgctcagtc
     5281 ggtgctggtg cgctggtatc acgaaggtct ggatgcattt gagcacacct gcccgaccgg
     5341 acgcactatt tacgatagcg tatacaacga tctgattaac tatctggctt caccggatca
     5401 aaccgaaggc tttgacgatc tgatcaaaaa ctgccgcgag caacatgaag cgctgaaagc
     5461 acagctggaa cagggtcgtg accgcctgct ggaaatccac tccaacggtg gcgaaaaagc
     5521 ccaggcactg gcagaaagca ttgaagagca ggatgacgat accaacctga tcgccttcgc
     5581 catgaacctg ttcgatatta tcggtatcaa tcaggacgat cgcggcgaca acatgatcgt
     5641 gctgacgccg tccgatcata tgctggtgcc ggacttccct ggcctgtcgg aagatggcat
     5701 caccatcacc tttgatcgtg aagtggcgct ggcgcgtgaa gatgcacagt ttattacctg
     5761 ggagcatccg ctgatccgca acggtctgga tctgatcctt tctggcgata ccggtagcag
     5821 cacgatttca ctgttaaaaa acaaagcgtt gccggtaggt acgctgttgg tggaactgat
     5881 ttatgtggtt gaagcccagg ctccgaagca gttgcagctc aaccgcttcc tgccaccgac
     5941 gccggtacgt atgctgctgg ataaaaacgg caacaacctg gcggcgcagg tagagtttga
     6001 aacctttaac cgccagctta acgcggttaa ccgtcacacc ggcagcaaac tggttaacgc
     6061 cgtgcagcag gatgttcacg ctatccttca actgggtgaa gcgcagatcg agaaatctgc
     6121 ccgtgcattg attgatgcag cgcgtaacga agccgacgaa aaactgtctg ccgagctgtc
     6181 tcgtctggaa gctctgcgtg cagtgaaccc gaacattcgt gacgacgaac tgaccgccat
     6241 tgagagcaac cgtcagcagg taatggaaag cctggatcag gcaggttggc gtctggatgc
     6301 cctgcgtttg atcgttgtaa cgcatcagta acggagccga aaatggggat ggaaaactac
     6361 aatccaccgc aggaaccctg gttggttatc ctgtatcagg atgaccatat tatggtggtc
     6421 aacaagccga gcggtttgtt gtcagtgccg ggtcgtctgg aagagcacaa agacagcgtg
     6481 atgacgcgca ttcagcgtga ttatccgcag gcagaatcgg tgcatcgtct ggatatggct
     6541 accagcggcg tgattgtagt ggcgctgacc aaagccgcgg agcgggagtt aaaacgccag
     6601 ttccgcgagc gcgagccgaa aaagcagtat gtggcccgcg tctgggggca tccatccccc
     6661 gcagaaggtc tggtggatct gccgctgatt tgcgactggc caaaccgccc gaaacagaaa
     6721 gtctgttacg aaacgggtaa acctgcgcag acggaatatg aagtggtgga gtatgcggcg
     6781 gataacacgg caagagtggt gttaaaaccg attaccgggc gttcgcatca attgcgtgtg
     6841 catatgctgg cgctgggtca tccgattctc ggcgatcgtt tttatgcatc accagaagcg
     6901 agagcgatgg caccacgttt gttgctacat gcagagatgt tgacgattac ccatccggcg
     6961 tatggcaata gtatgacgtt taaagcgcca gcggattttt aacctttcct gtacgtttat
     7021 accctcatcc taagggctgc ctcttgtaca taaatccccg agtccgggga ttttttgttt
     7081 ctgccaaact gctttcagtt gttgcgtgtg gctacgcttt ccattcggta attcccttcc
     7141 tgctccacag cgaatttttg aactttttct tcacccgttg accgtctctt atatttcatt
     7201 ttaacgggtc tgttatggtc ctttctgatt gttattcatg ggctaattag cagtctggtt
     7261 ggcgatgccc atctcggtga tccgtgtcct gcacgacgcc ttgcgtcact agcctcttct
     7321 ctagctcatc atgcaggtct ttctaattgt gaaatcatcc cacgctactg ctaaggttga
     7381 aggggcgttc cagccccttc aaccttagct tattctggct cattcaataa ttgcgttgtc
     7441 agtaatttgt tcagcagtac ttttttagta gcaacttctt cagtagcaac tcctttagta
     7501 tcaatttttt tgggggggat tttattaata ataattacct catcatatag ggaggtagca
     7561 ccgttcacgg tagcaccgtc caggatagca ccgtccgggg tagcaccgtc caggatagca
     7621 ccgtccgggg tagcaccgtc cggggtagca ccgcccaggt tagcattcca cccaggtctc
     7681 tcataaagga tatcattgct acctttcatt gttttttacc aaggtaacaa tccctcatgt
     7741 caacgccggg aaggtaagcc tttctaagat caacgcccaa gttaccttgg cccttatgca
     7801 gctgcaacgt ctgagtacat atcttattct tttcaatgaa aaaagtgaca cttaactcga
     7861 tatccccgaa ggtctgggcg acccagcgca tattgccctt tgcgaccaac tcatccggat
     7921 tttttgcgca tgttttaagt ttattgaata attccaggct attgataaac ttttctctct
     7981 cattctcgtt gatagcccca gtaaagtatt ctgaggcgtt gatgttgcca gtctggttat
     8041 tcacgaaatt gaacagaagt ttataagcct cagtctgttt atctgaccag aacagatggc
     8101 gtaacgtctc ccacaagcgt tgaaagatat tcatcttcac gtccatcttg tccccgctca
     8161 ccatcttata aatatcgttc ttgctcatat ttaaaagtgt aaccggcatg cctggaactg
     8221 atactttcat ggtaatagcc tcgcattgag ttaaaaactc atgatgcgcg ttctgaataa
     8281 atatactttc aaaaatcgct cattcaggta tgtgtttttt atttttaaga cgtaaaaata
     8341 taattccgct cgtcgtaaag ctctcaacct taagcagggt caacgcgata aaacctacag
     8401 aacccctccc gtaaaccgtg cattgagcct gtccaccatt ctgagtaaac gccttttctc
     8461 aaagaagtga ccgccagggc ggccaccttt aatcgtgggc agttactcag catcatttac
     8521 agggtcattt aaaccctttc tgctgcttta tcagctcata tgcctgctga atttcctgcg
     8581 ctttctgctt cgccatctcc atcatctcag gcggcaaacc tttcgccacc agcttatcgg
     8641 gatggtgttc actcatcagc ttacggtagg cacgtttgat ggtggtcgca tcatccgtcg
     8701 gcttcacgcc cagcacatta caggcatctt ccagcgttgg gccacgctgc gcttgctgcc
     8761 agttaccacc gccagtttgc tgctgataac cgccgccaaa ctgtgcaccg ccctgcatca
     8821 tgcgcaaaaa ctggtcaaac tgagcgcggg agatccctaa ttcttctgca atgacataca
     8881 gcaccgcccg ttcattcggg tgcagtgaac catcagcaaa cgccgcctga atctggatct
     8941 ccagaaacat acgaattaag tcaaaacgac caaagcagac actgcgaaac tggcgcatct
     9001 tttcgcgcag cgggtaattg tctgattttc ccacccggaa cgcattttgc gccgcagtac
     9061 gggaagcgcc atgaagattc attcggtcca tcaactggct ggcgatatga atatcagcct
     9121 ccgtgacgcg acctttggat ttggttaaat gccccatcac ttcaaaagtg gtggcaaaaa
     9181 acagcgcctg acgctcacgc tggttggcga accacgccat tttacggcta cgggctttat
     9241 caaacatatg gccaattaac aggcctaaca ctacgcccca aaagccgccg cccatcagta
     9301 aggccacggc cacgccaatg atttttcccc aatactgcat atattcccca aatcgacaca
     9361 cggatatcag ggctatctcc cacaatataa aggtgctttt accgttttcc ggctgcggtc
     9421 aattgtggga catcgcctat aatttgcatt atcatacctg tcattcaatg ccgtgcctaa
     9481 caccactgac gctattcgga caggattaac actagcgtag agatgacgag tacgttagtc
     9541 tctgaccgtt tgtcacgcgc aacgttaccg atgatggaac aataaaatca acgtatgaaa
     9601 aaacgtatcc ccactctcct ggccaccatg attgccaccg ccctttatag tcaacaggga
     9661 ctggcagccg acctcgcctc acagtgcatg ttgggcgtgc caagctatga ccgtcctctg
     9721 gtacagggcg ataccaatga cttacccgtg actatcaatg ctgaccacgc gaaaggggac
     9781 tacccggatg acgccgtgtt tactggcagc gtggatatca tgcagggtaa cagccgtctg
     9841 caggccgacg aagtgcagct ccatcaaaaa gaggcaccag gacaaccgga gccggtacgt
     9901 accgttgatg cgctcggtaa tgtccattac gacgataacc aggtgatcct caaagggccg
     9961 aaaggctggg cgaatctgaa caccaaagat accaacgtct gggaaggtga ttaccagatg
    10021 gtgggtcgcc agggtcgcgg taaagcggac ctgatgaaac aacgtggcga aaaccgctat
    10081 accattctgg ataacggtag ctttacctcc tgtctgccgg gttctgacac ctggagcgtg
    10141 gtaggtagcg aaattattca tgaccgcgaa gaacaagttg cggagatctg gaacgcccgc
    10201 tttaaggtgg gtccggtacc gatcttttat agcccctatt tgcagttgcc ggtgggtgac
    10261 aaacgtcgct ctggtttctt gatcccgaac gccaagtaca ccaccaccaa ctactttgag
    10321 ttctacctgc catattactg gaacatcgcg ccaaatatgg atgccaccat cacgccgcat
    10381 tatatgcatc gtcgtggcaa catcatgtgg gagaacgaat tccgctacct ctcccaggcg
    10441 ggcgctggct tgatggaact ggactatctg ccttcagata aagtctatga agatgaacac
    10501 ccgaacgatg acagttcacg tcgttggtta ttctactgga accactccgg ggtcatggat
    10561 caggtgtggc gtttcaacgt cgactacacc aaggtcagcg atcctagcta cttcaatgat
    10621 ttcgataaca agtacggttc cagtactgac ggctacgcaa cgcaaaaatt cagcgttggc
    10681 tatgcggtgc aaaacttcaa tgccaccgtt tcaaccaagc agttccaggt tttcagcgaa
    10741 cagaacacca gtagctactc ggcagagccg cagttagacg ttaattacta ccagaatgat
    10801 gttggtccgt ttgatacgcg tatttacggc caggcagtgc actttgttaa caccagagac
    10861 gacatgcctg aagcaacccg tgttcacctg gaaccgacca tcaatttgcc gctctctaat
    10921 aactggggca gcatcaatac cgaagcgaag ttgctggcaa cccattatca gcaaaccaat
    10981 cttgactggt ataactccag aaacacgacc aagctggacg aatccgttaa ccgcgtaatg
    11041 ccgcaattca aagttgacgg caaaatggtc tttgaacgcg atatggaaat gctggctccg
    11101 ggttataccc aaacgctgga accgcgcgcg cagtatttgt acgtgccgta tcgcgatcag
    11161 agcgacatct ataactacga ctcgtctctg ctgcaatctg actactctgg cctgttccgg
    11221 gaccggactt acggcggtct tgaccgtatt gcctccgcta accaggtgac gaccggtgtc
    11281 acatctcgca tatatgatga tgctgccgtt gaacgtttta atatttccgt tggtcaaatc
    11341 tactatttca cggagtctcg cactggcgat gacaacataa catgggagaa tgacgacaaa
    11401 acgggttcac tggtgtgggc aggcgatact tactggcgta tctccgagcg ttggggattg
    11461 cgtggcggga ttcagtacga tacacgtctg gataacgtag cgaccagtaa ctccagcatt
    11521 gaataccgtc gggatgaaga ccgtctggta cagctgaatt accgttacgc cagcccggaa
    11581 tatattcagg ctacgctgcc taagtactat tccactgctg agcaatataa gaatggtatt
    11641 tcgcagatag gtgctgtcgc cagctggcca attgccgatc gttggtccat tgttggggcc
    11701 tactactacg acaccaatgc taacaagcaa gccgactcta tgttaggtgt gcaatacagc
    11761 tcctgctgct atgcaattcg cgtcggttac gagcggaagc tgaacggttg ggataacgat
    11821 aaacaacatg cggtatatga caacgcaatc ggctttaaca tcgaacttcg cggcctgagc
    11881 tccaactacg gtctgggtac gcaagagatg ctgcgttcga acattctgcc gtatcaaaac
    11941 actttgtgat ttgttgattt accacgtaat ccgcagtgcg gttaattgaa atggaaaaag
    12001 tatgaagaac tggaaaacgc tgcttctcgg tatcgccatg atcgcgaata ccagtttcgc
    12061 tgccccccag gtagtcgata aagtcgcagc cgtcgtcaat aacggcgtcg tgctggaaag
    12121 cgacgttgat ggattaatgc agtcggtaaa actgaacgct gctcaggcaa ggcagcaact
    12181 tcctgatgac gcgacgctgc gccaccaaat catggaacgt ttgatcatgg atcaaatcat
    12241 cctgcagatg gggcagaaaa tgggagtgaa aatctccgat gagcagctgg atcaggcgat
    12301 tgctaacatc gcgaaacaga acaacatgac gctggatcag atgcgcagcc gtctggctta
    12361 cgatggactg aactacaaca cctatcgtaa ccagatccgc aaagagatga ttatctctga
    12421 agtgcgtaac aacgaggtgc gtcgtcgcat caccatcctg ccgcaggaag tcgaatccct
    12481 ggcgcagcag gtgggtaacc aaaacgacgc cagcactgag ctgaacctga gccacatcct
    12541 gatcccgctg ccggaaaacc cgacctctga tcaggtgaac gaagcggaaa gccaggcgcg
    12601 cgccattgtc gatcaggcgc gtaacggcgc tgatttcggt aagctggcga ttgctcattc
    12661 tgccgaccag caggcgctga acggcggcca gatgggctgg ggccgtattc aggagttgcc
    12721 cgggatcttc gcccaggcat taagcaccgc gaagaaaggc gacattgttg gcccgattcg
    12781 ttccggcgtt ggcttccata ttctgaaagt taacgacctg cgcggcgaaa gcaaaaatat
    12841 ctcggtgacc gaagttcatg ctcgccatat tctgctgaaa ccgtcgccga tcatgactga
    12901 cgaacaggcc cgtgtgaaac tggaacagat tgctgctgat atcaagagtg gtaaaacgac
    12961 ttttgctgcc gcagcgaaag agttctctca ggatccaggc tctgctaacc agggcggcga
    13021 tctcggctgg gctacaccag atattttcga tccggccttc cgtgacgccc tgactcgcct
    13081 gaacaaaggt caaatgagtg caccggttca ctcttcattc ggctggcatt taatcgaact
    13141 gctggatacc cgtaatgtcg ataaaaccga cgctgcgcag aaagatcgtg cataccgcat
    13201 gctgatgaac cgtaagttct cggaagaagc agcaagctgg atgcaggaac aacgtgccag
    13261 cgcctacgtt aaaatcctga gcaactaatg gttaaaaccc aacgtgttgt gatcactccc
    13321 ggcgagcccg ccgggattgg cccggactta gttgtccagc ttgcacagcg tgagtggccg
    13381 gtcgaactgg ttgtttgtgc cgatgccact ctccttacca accgggcagc gatgctcggt
    13441 ttgccgctca ccctccgccc ttattccccc aactcccctg cacaaccgca aactgcgggc
    13501 acattaacgc tacttcctgt cgcgctacgt gcacctgtca ctgcggggca gttagcggtt
    13561 gaaaatgggc attatgtggt ggaaacgctg gcgcgagcgt gcgatggttg tctgaacggc
    13621 gaatttgccg cgctgatcac aggtccggtg cataaaggcg ttattaacga cgctggcatt
    13681 ccttttaccg gtcataccga gtttttcgaa gagcgttcgc aggcgaaaaa ggtggtgatg
    13741 atgctggcga ccgaagaact tcgcgtggcg ctggcaacga cgcatttacc gctgcgcgat
    13801 atcgcagacg ctatcacccc tgcacttttg cacgaagtga ttgctatttt gcatcacgat
    13861 ttgcggacca aatttggtat tgccgaaccg cgcattctgg tctgcgggct gaatccgcac
    13921 gcgggcgaag gcggtcatat gggtacggaa gagatagaca ccattattcc ggtgctcaat
    13981 gagctgcggg cgcaggggat gaaactcaac gggccgctgc ctgccgatac cctgtttcag
    14041 ccgaaatatc ttgataacgc cgacgccgtg ctggcgatgt accacgatca gggtcttccc
    14101 gtgctaaaat accagggctt cgggcgcggt gtgaacatta cgctgggcct gccctttatt
    14161 cgcacatcag tggaccacgg caccgcgctt gaactggcgg gacgtggcaa agccgatgtc
    14221 ggcagtttta ttacggcgct taatctcgcc atcaaaatga ttgttaacac ccaatgaata
    14281 atcgagtcca ccagggccac ttagcccgta aacgcttcgg gcaaaacttt ctcaacgatc
    14341 agttcgtgat cgacagtatt gtgtctgcca ttaacccgca aaagggccag gcgatggtcg
    14401 aaatcggccc cggtctggcg gcattgaccg aaccggtcgg cgaacgtctg gaccagctga
    14461 cggtcatcga acttgaccgc gatctggcgg cacgtctgca aacgcatcca ttcttaggcc
    14521 cgaaactgac gatttatcag caggatgcga tgacctttaa ctttggtgaa ctggccgaga
    14581 aaatgggtca gccgctgcgt gttttcggca acctgcctta taacatctcc acgccgttga
    14641 tgttccatct gtttagctat actgatgcca ttgccgacat gcactttatg ttgcaaaaag
    14701 aggtggtgaa tcgtctggtt gcaggaccga acagcaaagc gtatggtcga ttaagcgtca
    14761 tggcgcaata ctattgcaat gtgatcccgg tactggaagt accgccgtca gcctttacac
    14821 caccacccaa agtggattcc gccgtcgtgc gcctggttcc tcatgcaacg atgcctcacc
    14881 cggttaaaga tgttcgtgtg ttgagccgca tcaccaccga agcctttaac cagcgtcgta
    14941 aaaccattcg taacagcctc ggcaacctgt ttagcgtcga ggtgttaacg ggaatgggga
    15001 tcgacccggc gatgcgagcg gaaaatatct ctgtcgcgca atattgccag atggcgaact
    15061 atctggcgga gaacgcgcct ttgcaggaga gttaacgatg atcaattcgc cccgagtgtg
    15121 tattcaggtt caaagcgtct acattgaggc tcaatcttca cctgataatg aacgttacgt
    15181 ttttgcttat accgtaacca tacgcaatct ggggcgagcg ccagtgcagt tgttggggcg
    15241 ttactggctg atcaccaatg gcaatggccg tgaaaccgaa gtccagggcg aaggagtggt
    15301 tggcgtccag ccacttatcg cgcctggcga agagtaccag tacaccagcg gtgcaatcat
    15361 tgaaaccccg ctgggcacca tgcagggtca ctacgaaatg atcgatgaaa atggcgtccc
    15421 tttcagcatc gacattcccg tattccgact cgccgttccc acactcattc attaaaagaa
    15481 tatggcgaca taccttattg gcgacgttca tggttgttac gatgaactga tcgcattgct
    15541 gcataaagta gaatttaccc ctgggaaaga taccctctgg ctgacgggcg atctggtcgc
    15601 gcgcgggccg ggttcgctgg atgttctgcg ctatgtgaaa tccttaggcg acagcgtacg
    15661 tctggtgctg ggcaatcacg atctgcatct gctggcggta tttgccggga tcagccgcaa
    15721 taaaccgaaa gatcgcctga caccgctgct ggaagcgccg gatgccgacg agctgcttaa
    15781 ctggctgcgg cgccagcctc tgctgcaaat cgacgaagag aaaaagctgg tgatggccca
    15841 cgcagggatc acgccgcagt gggatctgca gaccgccaaa gagtgcgcac gcgatgtaga
    15901 agcggtgcta tcgagtgact cctatccctt ctttcttgat gccatgtacg gcgatatgcc
    15961 aaataactgg tcaccggaat tgcgggggct gggaagactg cgttttatca ccaacgcttt
    16021 tacccgtatg cgtttttgct tcccgaacgg tcaactggat atgtacagca aagaatcgcc
    16081 ggaagaggcc cctgccccac tgaaaccgtg gtttgcgatt cctggccctg tcgctgaaga
    16141 atacagcatc gcctttggtc actgggcatc gctggagggc aaaggtacgc cggaaggtat
    16201 atacgcgctg gataccggct gctgctgggg tggtacatta acctgcctgc gctgggaaga
    16261 taaacagtat tttgtccagc cgtcgaaccg gcataaggat ttgggcgaag cggcggcgtc
    16321 ttaaacacag cctgatatag gaaggccgga taagacgcga ccggcgtcgc atccggcgct
    16381 agccgtaaat tctatacaaa attaccgccg ctccagaatc tcaaagcaat agctgtgaga
    16441 gttctgcgca tcagcatcgt ggaattcgct gaataccgat tcccagtcat ccggctcgta
    16501 atccgggaaa tgggtgtcgc cttccacttc tgcgtcgata tgcgtcagat acagtttttg
    16561 cgcttttggc aagaactgtt cataaacgcg accgccgcca atcaccatga tttctggtac
    16621 gtcaccacac gccgcgatgg cttcatccac cgacttcacc cacgttacgc gatcgtccgt
    16681 acccggttga ctgctgagga taatattttt gcgtcctggc aacggacgac cgattgattc
    16741 ccaggtatgg cggcccataa tcacgggttt atttaaggtg ttgcgtttaa accaggcgag
    16801 atcggcaggc aggttccacg gcatggcgtt ttccatgccg ataacgcgat ctaccgctaa
    16861 cgccgcaatc agactgatca ttgagatttc ccgataaaaa aattgtcgcc actatacgta
    16921 aagcgtaaac cgtcgtcgac tggtgcgagg atgatgttga ggaaaatttt atattctgct
    16981 ggcgagtcca cgctctctcc ctggactcgc cgcattacaa tgaaacaaaa acaaacagtt
    17041 agctgtaaag tgtgatttac gtcactcttt attaggatga gggtttcgtt tccggttcat
    17101 ccgccatgtt gccggtatgt ttaccttctt cggttccctg ccagccatgt cgttgaatta
    17161 atgacagatg ttcgcggtcc tcggtaatga tctcacttaa catcgcgctg gtgcgtttat
    17221 agaccgccgc gcgggctttg gtgtcgttct caaccattgc catctcttcc accatctgaa
    17281 tattaaagcg gcggaacaca tcggcacgtt ctcgcgcttc atacggcccc agacctaaac
    17341 tttccagtgc cagacgcccg gttttcagcg caccttcgaa ggtttcacgc tccggctttt
    17401 caacgcctgc ctgacgcaaa cgaatgtagt ggtcgacatc gcgggcgcgg gcaataatct
    17461 gcaaatgcgg gaaatgttct ttcaccatct ctgtcagttg caggttggtt tgcggatcgt
    17521 cgatggcgtt aatcagcact tccgctttcg ccgctccggc agattccagt aaatccatcc
    17581 gcgtggcatc gccataaaac actttcatac caaatttacg caaggtttcg atatggtccg
    17641 gatcgtgatc gagtaccacc attttcaccc cgctggagag cagtaaacgt ccggtaatct
    17701 gcccaaaacg accgaatccg gcgataatca cgcgcggctg ttcttcgtcg atctcatcgg
    17761 cttcacgcgc ttcctcagta gaagattgct caaggcgatt gaggatcacc agcagaatcg
    17821 gcgttgctgc catcgacagc gccaccgcca gggtcagcga tttcgcccac tccggctcca
    17881 gcacattcgc catctgcgcc gcgccaaata ccacaaaggc aaactcactg ccctgcccta
    17941 acaacaccgc aaaccaacga cgctgtttat ttggcacttg caacggtcgg gcaatcagcc
    18001 acagcatggc gattttgatg atgaggaaac cgagcagcaa aatgacaatg cgcaatgggt
    18061 tttcaagcag cgtgccaaag tctatcgaca tgccaacacc gatgaaaaac agccccaaca
    18121 gcaaaccttt aaatggttcg atatcgctct ccagcgcatg acggtattcc gagcttgcca
    18181 gcagtacgcc cgccagaaac gcgcccatcg ccatcgacaa gccgacctct tccagcagca
    18241 aaccaaagcc aaacacgagg aataacgcca cggcactaaa cacttcccgc aagccagagc
    18301 gggctacaaa acgcagcgcc ggacgcgtga catagcgccc cagcaatacc accagcacca
    18361 gcgcacccgc cacttttaac gccgagagag caaatgcgcc catcgtcgtc gaggcactgc
    18421 tcgttgccag tagcggaatc atcgccacca gcgggatcgc cgcgatatcc tggaacagca
    18481 gcaccgcaaa ggcactgcga cccatttgcg tcaccatcag attgcgttca ttcatcgcct
    18541 gcatggcaat cgccgtagag gagagcgcca gcgtcatgcc gatcaattcc gcgacctgcc
    18601 agcgcagccc aagtaacatg cagaacagcc ccagcaggcc gccgcaaatc accatctgca
    18661 atgcgccaca gccgaacact gccgcacgca gcttccacag cctttgtgga tcgagttcga
    18721 ggccgataat aaacagcatc agcaccaccc caatctcggc aaagtgcaga atagattcgg
    18781 catcggtcac cagtcgcagc ccccacgggc caataatgca gccggcgatc aggtagccaa
    18841 gtaccgatcc cagaccaaga cgtaccgcaa tgggtacaat cagcgctgcc gaaccgagat
    18901 aaatcagcgc ctgaatcagc gtatggctat ccatgatggg cctcctgcca ttccagcaga
    18961 cgttgcttat agtgacgcgc ctgcccttcg agggtttcgt cgtcacaaat aaaggtgcag
    19021 tgcatggcaa acggtggcag ccagttcagc ccgcagtaga ttgccgtcgc ctgtagcggc
    19081 tgcgacagca catcaaagcc cggatgcgca ccaatttcaa aatggctttc cccgccgccg
    19141 gtcgtcaccg cccacagcaa atgtttgcca tgcagcgccg tgccgccatg accgtaagcc
    19201 cagccgtggg agaaaacttt atcgatccaa agtttgagga gcggaggaat gctgtaccac
    19261 tgcatcggat gctgccagac gatcagatcg gcgcgagaca acgcctcctg ctcggcggca
    19321 atatcgatat tgaagtcagg atagagttga taaagagagc gaatttcgac gccttccagc
    19381 gtccttgcct gttcaagcat ccgtttattc gcatgggaat gatgcggata cggatgcgca
    19441 taaattataa gaatcatagg tagcccgcgt gattacgcct ttgttttccc acaaagtgta
    19501 gtcatatatt cacgcggctt atagtcaata atattgattc agaaaagaga gaaatctgaa
    19561 caatttaccc cattctctgc ccgcggatcg tcatattgct ggtctgcgcc agtgacatcc
    19621 ctcgagtctc cggggcaaac gctacggaaa tcaacaagcc aaacagcgag atacccgccc
    19681 ccattagcat cgtgttactg ataccgtaat tattgataaa gatcggtagt gcccaggtcg
    19741 aaacaatggt gccaatacga cttaaggaca taatcacgcc cacggcagag gcgcggatat
    19801 ctgtcgggaa gagttcatta ggatagagcc actgcaaatt acccggcccg ccagagaaaa
    19861 aggcatacac cgcaaaggcc atcactacca gccagatccc catatccggg attagcccca
    19921 aaaccgccag cgccagcgtc atcatggcaa agctgccaat caacaatgga cgccgtccgg
    19981 cagtgtttaa ccacagcatc ggcggaatac agccgagcat aaagaacagg ctaatcacca
    20041 cattccctag tgccgcgttt ttgccaaccc ccaatcccaa caaaccaacg atttgcgggc
    20101 caaaggtgta aatggcgaac attgggatca cctggcaggt ccagatggcg gcaacaaaca
    20161 gaacaaaagg aaaatggcgg cgattaaaca gatcgcgaaa acgggtttgc tgcggctgct
    20221 cttcatcgaa agccaccggt tcgccaaaca gtttgatcat catctcttcg cactctttta
    20281 ctcgcccttt gcgtaataac cagcggggag attcaggcag ttcgaatcga ccaatcaaaa
    20341 tcaacaaaca ggggatcgcc gcgctaccca gcatccagcg ccagccgcct tccacatcat
    20401 aaagccagta gccgaccaga tcggcacagg tcgcgccgac ataccacatc gcggcaataa
    20461 agctgatgga aaacgcccgc tgacgggtac tggagaactc ggtgatcatt gaggtggcga
    20521 tgggataatc tgcaccgatg acaatgccga taagtacccg catcaccaac agttcgacgg
    20581 gggatgaaac aaacatcgtc gccaccgata tcacgccgat ggcgatgata tcaatgagga
    20641 acattttgcg ccgtccgact ttatcggaaa tataaccaaa cagcgatgtg ccaacgaaca
    20701 gcccggcgag cgttcccgcg cccagcaagc caatccagtc agcgtccagt ttcagcgccg
    20761 gcgtcagttg ctccagcgcc acgccaatca ttaccagtac ataaccatcc agaaacggac
    20821 caccgcttcc ccacagcaaa atgcggcggt gaatagagga gaatttgaga tcgtcaaagt
    20881 ttctggacgg ttgcatggtt attcctgttt tttgcaatga gagtcagtgc ggcgttacgt
    20941 atcaaaccaa catcagccgt aacggaactc cacaccaaag gtgccgcgcg ggtattccca
    21001 ctgttccagc gccgacccca gccccagaat gcgacaggtg ccgcactcca gacatccggc
    21061 gtaatcgaag cgcacactgc cgtcatcctg cttcttgtac agacctgcgg ggcacgcttt
    21121 caccagcagc tccagcgcct gtttatcagc atcggccttc acaacaatgt gcggatgctc
    21181 ttcatcgaca ttgaatttat tgacgcccag tttgacgtcc acattgacgg gagaagtcat
    21241 aaaacggtca ctcctttcat gccatccttg attagattga tgaagcccac tttcttgccg
    21301 tggcggagga ttttcttgcg catcagttcc ggcgcgctgc catcaatggt gaacaggtca
    21361 cgcgccacac ccaccgccag ctccgggtag ccgctaaaca tgcgtgggtt atcaaggaac
    21421 gccggtagtt tctggtacat acgcatatcg cgcagcggac cactctcaag atgctgacga
    21481 tattccgcca gtttttgctt actgaaatcg tcgcttttca tcgctgaaag cacggttttt
    21541 gctgcggctt ccccggcggc aatcgccaga tccataccgc gaatggtaaa accgaggttc
    21601 atacacattc cggcggcatc accggcaatc aatacgccgt caccaaccaa ctccggcagc
    21661 atgttgatgc ctgcttccgg cactacgtga gcggaatatt ccaccagctt gccgcccgcg
    21721 atcagcggtg caacggccgg atgctgtttg aaatcttcca gcatttgcgg caccgatttt
    21781 ttcgcgtcat gcagatgatg caaaccacaa accagcccca gcgacagggt gttttcattg
    21841 gtataaagga agccgccgcc catcaggcca tcggtgggtg atcccgcaaa caggcaagcc
    21901 gccccctgat taccctgcaa ctgaaaacgg tcttcaataa ccgacttcgg taactcgatc
    21961 agttccttca cgccaaccgc cacatccgtc ggtttgacgc gttttgccat ccccaatttt
    22021 tcggcaagga tggagttcac cccatcagca aggatcaccg ttttcgcttc aatcacatcg
    22081 ccatcggctt ctacaccgac gactttgcca tcgcgctgta cgaggttatc gacgcggatc
    22141 ccggtaatta actgcgcgcc cgcttcttcg gcctgctcca tcagccaggc atcaaattta
    22201 ctgcgcaaaa cggagtaaga acgctgggat ggcgaggttt cgtcaccatt gcagtagtcc
    22261 atagtcatcg ctgacttttc cgtcataaac gcgagttttt catgggtgat caggcgttct
    22321 acgggggcgg agtcggcgaa accaggaata atgtgttcca gactgtgggc atagagacgc
    22381 ccgccggtga cgttcttggc acctgcggaa ttgccacgct cgataactaa cacttgcgca
    22441 ccttcgcggg cgagcaccag tgcggcaacc gaaccggcaa gccctgcacc gacgatgatg
    22501 gcgtcaaaga tatcttcgga cataagagct ccctgtcagc ggcagggcca aaatgcagcc
    22561 ctgccagagt ggatcaacgc gctaaagctg cggtcagcgc cggaaggatc ttcacggcgt
    22621 cgccaacaat gccgtaatcc gcgtactgga agatcggcgc atttttatct ttattgatgg
    22681 cgaaaatggt ttgcgacgcg ttagcgccaa ccatgtgctg gatctgcccg gagatcccca
    22741 ccgccaagta cagttcaggt ttcagcatca ggttggagat accgacatag cgttcgtgct
    22801 ccatccattt ttcgttttcc gccaccggac gagaacaggc caactccgca cctatcgcct
    22861 tgcaaagctg ttctgccagc gcaatgttct ctttgctgcc aataccgcga ccgacgctga
    22921 ccaccagacg ggctttgtcg agatcgacgc tgttgctctg gcgcgcctgg gttgccgtgc
    22981 gggtaatcgc cacagccgga gcctgccact ccacggtgtg cgtttcgcca gtgcgtgacg
    23041 cgtctggctg agccgcatcg aacgtgccgc tgctgatggt cagtaccgca tacggcgtgg
    23101 caatgcgttc ttcgccaatc gccagaccac cgtaaaccat gtgtttcact gtcgctttac
    23161 cgtcctgtac gctgacggtg ctggcatcgt tagacaccgc cgctttaagg cgataaccca
    23221 gttttgccgc cagtaatttg ccgcgacggg tgtttggcag cagcaccagg ccgtctgcgc
    23281 cgtgctggcg aatagtgtca gccatgacac cggcgtaatc ttcgatcatc cgatcgtccg
    23341 gtttgccgtt taatttccag acatgattag cgccgagctg gattgcctgt gcgccgtcgg
    23401 catcattgag gacaaaggtg ttgatttgat tagctaaagc ctgcgcaccg ttcatcagtt
    23461 ccggcagacg agaaggggta tcgctgaata cccagacttg agaaaacgtg ttcatagcat
    23521 cccctgtaat taaatgactt tgcgaagatt ttcagcaaat gcggcgatct gttcttcgcc
    23581 gtcgccttca atcacgatgc gctgacgttc gcgctgtttc ggcgcggcaa cctgttgttc
    23641 tgaccaggct gcctctgcgt taaaaccaat atccgccgcc gaccatacct ggacgggctt
    23701 tttcgccgcg ccgagaatgg ctttcatcga aggaatttgt ggggaattga tatcagtgga
    23761 aacagcaaca accgcaggca gcggaatgct taaggtttcg gtttcatctt ccagttcgcg
    23821 ctcaacggtg agggtatctg cagtcaggga gataattttg ctgacgccgt taactgccgg
    23881 aatattgagg atttcgccta ccagcaaacc aacctgctgg gcataaaggt cggaagaacc
    23941 atcgccacag aggatcaaat caaagcctgc tttctgggcg gctgcagcca gtgcgctcgc
    24001 cgtttgttgc ggcagtgcct gctcgaactg gtcatcaatt accacaatca gttcatccgg
    24061 gccgcgcgat aacacatctt tacgcccttt ggcgttggtc agggctttac cgcccacact
    24121 taaggctgtc acctgcgcct ctgctgcctg ttgctttagc tggcaagccg cttcaatagc
    24181 gttgagatcg tattggctta ttttggcatc ggctttgctg aagtctaatg aaccatcagc
    24241 attattgacc gcaatatcct gttcatcagg cacgcactta tagcaagtaa taatcttcat
    24301 tgcatctcca gaaatcatga aggaaacgtc gttcatatcg gtggtgttaa ttacagatat
    24361 cacgcccttt aatttggaaa taaaacttta atcaccaata ttgaaaatgt cacacgcaga
    24421 taaatccaac tttcaatatt gttaagttcc tcaccaatat tgaaaacacg gcgtagcaaa
    24481 aagaaatttt caatattgtt ttatggatca ccaatattga aagtcagatg ttattttttt
    24541 actcacaata gagcataaca aactgattat taatcaaaat taacgaaaaa acgccctcta
    24601 ttcacccgaa acaaaaatgt gataccaatc acagaataca gcttattgaa tacccattat
    24661 gagttagcca ttaacgcgtc cacgaggtta ataataatta tattaaatgt taacaaaaat
    24721 aaaacaaacg ggaacgcaaa ataaatattc gttttcacag tggaattaac tcatgaagaa
    24781 tgaaaagaga aaaacgggaa tagaaccgaa ggttttcttt ccgccgttaa taatcgtcgg
    24841 catactttgt tggcttacag tcagagatct ggatgcagcg aatgtcgtta ttaatgctgt
    24901 attcagttac gtcaccaatg tatggggatg ggcatttgaa tggtatatgg tggtgatgct
    24961 tttcggttgg ttctggctgg tgtttggccc gtatgccaaa aagcgtttag gtaacgaacc
    25021 gccagaattt agcaccgcca gttggatctt tatgatgttc gcctcctgta cgtctgctgc
    25081 cgtactgttc tggggatcga ttgagatcta ctactacatc tccaccccgc cgtttggctt
    25141 agaaccgaac tcgacagggg cgaaagagtt ggggctggct tacagcttgt tccactgggg
    25201 acctctgccg tgggccactt acagcttcct ttcagtcgcc ttcgcttact tcttctttgt
    25261 ccgcaaaatg gaagtgattc gccccagctc gacactggtg ccgctggtag gtgaaaaaca
    25321 cgccaaaggg ttgttcggca ctatcgtcga caacttctat ctcgtcgcct tgatcttcgc
    25381 gatgggtacc agtctgggcc ttgccacgcc gctggtgacc gagtgtatgc aatggttgtt
    25441 tggcattccg cataccctgc aactggacgc tatcatcatt acctgctgga ttatcctcaa
    25501 cgccatttgc gtcgcttgcg gtctgcaaaa aggggtacgt atcgccagtg acgtgcgtag
    25561 ttacctgagc ttcctgatgc tgggttgggt gttcattgtc agcggtgcca gcttcatcat
    25621 gaactacttc accgattcgg tggggatgtt gctgatgtat ctgccgcgca tgttgttcta
    25681 taccgatccc atcgctaaag gcggcttccc gcagggctgg accgtgttct actgggcatg
    25741 gtgggtgatt tatgctatcc agatgagtat cttcctcgcc cgcatctccc gtggtcgtac
    25801 tgtgcgtgaa ctgtgcttcg gcatggtgct ggggctgaca gcgtcaacct ggatcctgtg
    25861 gactgtactc ggtagtaaca ctctgctgtt gatagataaa aacatcatca acattccaaa
    25921 tctgatcgaa cagtacggtg tggcgcgcgc catcattgaa acctgggccg ctctgccact
    25981 cagcaccgcc accatgtggg gcttcttcat cctctgcttt attgccaccg ttacgctggt
    26041 taacgcctgc tcttataccc tggcgatgtc cacttgccgc gaagtacgcg atggtgaaga
    26101 accaccgctg ctggtgcgta tcggctggtc aattctggtt ggcattatcg gtattgttct
    26161 gctggcgctc ggcggcctga aaccgattca aaccgccatt atcgccggag gatgcccgct
    26221 gttcttcgtc aacattatgg tgacgctctc ctttattaaa gacgcgaaac agaactggaa
    26281 agattaatta acccccaaaa tatcaagagg ttgaaagatg gattttaatt taaatgatga
    26341 gcaggaactg tttgtcgccg gtatccgcga actgatggcc agcgaaaact gggaggccta
    26401 ttttgccgag tgcgaccgtg acagcgtcta cccggaacgt tttgtcaaag cactggcgga
    26461 tatgggtatc gacagtctgc tgatccctga agagcacggt ggtctggacg cggggtttgt
    26521 tactctcgcc gccgtgtgga tggagctggg acgtctgggg gcaccaacct atgtactgta
    26581 ccagttgccg ggcgggttca ataccttcct gcgcgaaggc acacaagagc agatcgacaa
    26641 gattatggct ttccgcggca ccggtaagca gatgtggaac tcagcgatta ccgaaccggg
    26701 cgcgggctcc gacgtgggta gcctgaaaac gacttatacc cgtagaaatg gtaagattta
    26761 tcttaatggt agtaagtgtt ttattaccag tagcgcctac accccgtaca tcgtggtgat
    26821 ggcgcgcgac ggggcttctc cggacaaacc tgtctacacc gaatggtttg ttgatatgag
    26881 caaaccgggc atcaaagtga ccaaacttga gaagctcggt ctgcgtatgg atagctgctg
    26941 tgaaatcacc tttgacgatg tggaactgga cgagaaagac atgttcggtc gggaaggtaa
    27001 cggctttaac cgcgtcaaag aagagttcga ccatgaacgt ttcctggtag ccctgaccaa
    27061 ctacggtacg gcgatgtgcg cctttgaaga tgcggcgcgc tacgccaacc agcgcgtgca
    27121 gtttggcgag gctattggtc gtttccagtt gattcaggaa aaattcgccc acatggcgat
    27181 caaattaaac tccatgaaaa acatgctgta tgaagcagcg tggaaagcag acaacggcac
    27241 catcacctct ggcgatgcag cgatgtgcaa atacttctgc gccaatgcag catttgaagt
    27301 ggtggatagc gcaatgcagg tgctgggcgg tgtcgggatt gcgggcaacc accgcatcag
    27361 ccgcttctgg cgtgatctgc gtgtagaccg cgtctccggg ggatctgacg aaatgcagat
    27421 cctgacgctg ggtcgcgcgg tgctgaagca ataccgctaa gtccgtgcgc tgcctgatgc
    27481 gacgctgacg cgtcttatca ggcctacggt cggccggata aggcgtttac gccgcatccg
    27541 gcagtcatgc gctacataaa tttttcagga gctaataatg gatcatctac ccatgccgaa
    27601 attcgggccg ctggccggat tgcgcgttgt cttctccggt atcgaaatcg ccgggccgtt
    27661 cgccgggcaa atgttcgcag aatggggcgc ggaagttatt tggatcgaga acgtcgcctg
    27721 ggccgacacc attcgcgttc aacctaacta cccgcagctc tcccgccgca atttgcacgc
    27781 gctgtcgtta aatatcttca aagatgaagg ccgcgaagcg tttctgaaat taatggaaac
    27841 caccgatatc ttcatcgaag ccagtaaagg tccggcattt gcccgtcgtg gcattaccga
    27901 tgaagtcctg tggcagcaca acccgaaact ggttatcgct cacctgtccg gttttggtca
    27961 gtacggcacc gaggagtaca ccaatcttcc ggcctataac accatcgccc aggccttcag
    28021 tggttacctg attcagaacg gtgatgttga ccagccaatg cctgccttcc cgtataccgc
    28081 cgattacttt tctggcctga ccgccaccac ggcggcgctg gcagcactgc ataaagtgcg
    28141 tgaaaccggt aaaggcgaaa gtatcgacat cgccatgtat gaagtgatgc tgcgtatggg
    28201 ccagtacttc atgatggatt acttcaacgg cggcgaaatg tgcccgcgca tgaccaaagg
    28261 taaagatccc tactacgccg gttgcggtct gtataaatgc gccgacggct acatcgtgat
    28321 ggaactggtg ggcattaccc aaattgaaga gtgctttaaa gatattggcc tcgcacatct
    28381 actcggtacg ccggaaatcc cggaaggcac tcagcttatc caccgtatcg aatgccctta
    28441 cggaccactg gttgaagaga aactcgatgc ctggctggcg gcacatacca tcgcagaagt
    28501 taaagaacgc tttgccgaac tgaatatcgc ctgtgccaaa gtacttaccg taccggaact
    28561 ggaaagcaat ccacagtatg tggctcgcga atcaatcact cagtggcaaa cgatggatgg
    28621 tcgcacctgc aaagggccga atatcatgcc gaaattcaaa aataaccctg gacaaatctg
    28681 gcgcggaatg ccctcacatg gcatggacac ggctgccatt ttgaaaaata tcggctacag
    28741 cgaaaacgac attcaggagt tggtcagcaa aggtctggcc aaagttgagg actaaacgcg
    28801 tggcgtcagt cagcttgcct gactagcgcc cgctcaataa caaacgaaca acaatggata
    28861 gaggtgcaat ggatatcatt ggcggacaac atctacgtta aatgtgggac gatctggcgg
    28921 acgtttacgg tcataaaacg gcgctaattt gtgaatccag cggcggagtc gttaaccggt
    28981 atagttatct tgagttaaat caggagatta accgcacggc aaacctgttt tatacgctgg
    29041 ggattcgcaa aggcgacaag gttgctctac atctcgacaa ctgcccggaa tttatctttt
    29101 gctggttcgg gttggcaaaa attggcgcga ttatggtgcc gattaacgcc cgcctgttgc
    29161 gcgaagaaag cacgtggatc ctgcaaaata gccaggcgtg cctgctggtg accagtgcgc
    29221 aattttatcc tatgtatcaa cagattcagc aggaagatgc ctctcagttg cggcacattt
    29281 gcctgacaga tatggcactt cccgctgatg atggcgtgag ttcgtttact caactgaaaa
    29341 atcaacaacc tgccaccttg tgctatgcac cgccgctatc gactgacgat acggcggaaa
    29401 ttctcttcac ctccggcact acctcccgat cgaaaggggt ggtgattacc cattacaacc
    29461 tgcgcttcgc tggatattac tccgcctggc agtgtgcact gcgtgacgat gacgtctacc
    29521 tgacggtaat gcctgcgttt catattgact gccagtgtac tgcggcgatg gcggcgtttt
    29581 ctgccggggc cacctttgtg ctggtcgaga aatacagcgc ccgcgccttc tggggacagg
    29641 tgcagaagta ccgcgccacc attaccgaat gtattccgat gatgattcgt acgttgatgg
    29701 tgcagccgcc ttcagcgaac gatcggcaac actgcctgcg ggaagtgatg ttttatctca
    29761 acctgtcgga gcaggaaaaa gacgcgtttt gtgaatgctt cagcgttcgc ttgctgacgt
    29821 catatgggat gacggaaacc attgtgggca ttatcggcga tcgccctggc gataaacggc
    29881 gctggccgtc gattggtcgg gcgggctttt gctacgaagc ggagatccgc gacgatcaca
    29941 atcgtcccct cccggctggt gagctcggtg aaatctgtat taaaggcgta ccagggaaaa
    30001 ccatcttcaa agagtatttt ctcaacccga aagccactgc gaaagtgctg gaagccgatg
    30061 gctggctaca taccggcgat accggatacc gcgacgaaga gggctttttt tatttcgtcg
    30121 atcgccgctg caatatgatc aaacgcggtg gcgagaatgt ctcctgcgtg gagctggaaa
    30181 atattatcgc cgcgcacccg aaaattcagg acatcgtggt tgtgggtatt aaagattcga
    30241 ttcgcgatga agccatcaaa gcatttgtgg tgctgaatga aggtgaaaca ttgagcgaag
    30301 aggaattttt ccgcttctgc gaacaaaata tggcgaaatt taaagtgccc tcttatctgg
    30361 agatcagaaa agatctgcca cgtaattgct cggggaaaat aattagaaag aatctgaaat
    30421 aaatgaaacg gcagggaact accctaccag ctaataatca cactctaaaa caatatgcat
    30481 tttttgcagg gatgttgtcg tccctgaaaa agcaaaaatg gagaaaagga atgagtgaat
    30541 cattacatct gacccgcaat ggatcaattc tggaaattac ccttgatcgt ccaaaagcga
    30601 atgctattga tgcaaaaacc agctttgaaa tgggcgaagt atttctaaat ttccgtgacg
    30661 atccgcaatt acgtgtcgcc attattaccg gtgccggaga gaagttcttt tccgcgggct
    30721 gggatttaaa agcggcagca gaaggcgaag caccggatgc tgactttggc ccgggtggat
    30781 ttgcgggatt aaccgaaatt ttcaatctcg acaaaccggt tatcgcagct gtgaacggct
    30841 atgcctttgg cggcggcttt gaactggcgc tggcggcaga ttttattgtt tgtgccgata
    30901 atgccagctt cgccctgccg gaagccaaac tgggcatcgt tcctgacagc ggcggcgtgc
    30961 tgcgtctgcc gaagatcctg ccgcctgcca tcgtcaatga aatggtgatg accggcagac
    31021 gaatgggcgc agaagaggcg ctgcgttggg ggatagtcaa ccgcgtggtt aaccaggcgg
    31081 aactgatgga taacgcccgc gaactggcgc agcagctggt taacagcgcc ccgctggcga
    31141 ttgcggcgct gaaagagatc taccgcacca ccagcgaaat gccggtggaa gaagcgtatc
    31201 gctatattcg cagcggcgtg ttgaaacact atccgtcggt tctgcattcg gaagatgcca
    31261 ttgaagggcc gctggcgttt gccgagaagc gcgatccggt gtggaaagga cgttaacaac
    31321 cgtgagctat tacgcctttg aggggttaat tccggtggtt cacccgacgg cgtttgtcca
    31381 tcccagtgcc gtcttgattg gcgatgtgat tgtgggagcc ggtgtctaca tcggcccact
    31441 cgcctcactg cgtggtgact acgggcggtt gatcgtgcaa gcgggagcca atattcagga
    31501 tggctgcatt atgcatggct actgcaacac tgacaccatc gttggggaaa acggtcatat
    31561 cgggcacgga gcgatcctgc atggttgtgt gattggtcgc gatgcactgg tcgggatgaa
    31621 cagcgtgatt atggatggcg cggtcattgg cgaagagagc attgttgccg ctatgagctt
    31681 tatcaaagcg ggctttcgcg gcgagaaacg ccagttgttg atgggtacgc cagcccgcgc
    31741 tgtacgcagc gtgagtgacg acgagttaca ctggaaacgg ttgaatacca aagagtatca
    31801 ggatcttgtc gggcgctgtc atgcatcgtt gcatgaaacg cagccactga ggcaaatgga
    31861 ggaaaatcgc ccccgtttgc aggggacgac ggatgtgacg ccgaaacggt gatctttccg
    31921 gatgcggcgt aaacgcctta tccgacctgg ctggaaagga accgtaggcc gtataagatg
    31981 cgccagcatc gcatccggcg accaggtcgc acggtatcaa cgaaacgaca ttaacgacgc
    32041 atactctttg acaacatcat ctgccacttc tgctcgcggt taagttccgt gagcggaacg
    32101 gcaggaatac gcggcgtctt tcttacgccg actaattttt cccgactgtt attgcgcagg
    32161 cgcgcgtaaa tttgctcatc gatatcgacc actttaacca gtcgctgaca ctggcatccc
    32221 cgcccttcca gcttattagg gatcatctta acttcgcagc ttatttctgt gacttccgac
    32281 agaatataag tcagggtatt aaccgccttg ctgtgttcaa tatcgaaatg aatagagatc
    32341 tctcttgcta tcacccaccg attttcagcc atcatccatt cggcgattaa caagtagagt
    32401 ggtttttcaa catatccttc acacatacga actccagttt cacaaattaa aagtctggct
    32461 atgactcgtt ttgaagcaat taaacaaggc catattaaaa ttgtggatat atcgatagta
    32521 tgcaacttca ccgtcgataa gtgtgagcta aatcctgctt atgtcatcaa aaatatcgat
    32581 tccccaaaag atttacttaa tgggcaaaaa aaacggtcct catcagagaa ccgtattagt
    32641 tattcgatca aattagcgga tgaaaaatat ccgccatgac acgctattat ttgatctgcg
    32701 cgtgcatttc ctgcaccgaa attacttttt cggtcgcatc agcattcagc gccatcgcag
    32761 tagcgaaacc accgttcagg gtggtgtcat aatgcacttt atattgcagc gcactgcgac
    32821 gaatcacgcg ggagtcttca atcgcgcgac gacctgaggt ggtgttgatg atgtaggtat
    32881 attcgccatt cttgatgcgg tcctgaatgt gcggacggcc ttcatgcacc ttgtttacca
    32941 gacgcggatt gatacccgct tcgcccagca caatcgccgt gccgtgggtc gcatccagct
    33001 cgaagccctg tttcagcagt tttgccgcca ggtccaccac gcgttctttg tcgccttcgc
    33061 gcacggaaag cagcgcacga ccgtgtttct tcatggtgga gttgctgccc agctgcgctt
    33121 tggcgaacgc ttcagcgaag gtgcggccca cgcccatgac ttccccggta gagcgcattt
    33181 ctggccctaa cagcgggtca acgccgggga atttattgaa cggcagcacc acttctttca
    33241 ccgagtagta cggagggata acttctttgg ttacgccctg ctcggccagc gttttgcctg
    33301 ccatcacgcg cgccgccact ttcgccagcg gtacgccggt ggctttggag acgaacggaa
    33361 cggtacgcgc cgcacgcggg ttaacttcaa tcaggtagac ttcgttgttt ttaaccgcaa
    33421 actgcacgtt catcaggccg cgcacctgca attcgaaggc cagtttctgc acctgctggc
    33481 gcatcacatc ctgaatttcc tgacttaagg tgtaggctgg cagagaacat gcggagtcac
    33541 cggagtgcac gcccgcctgc tcgatgtgct ccatgatgcc gccaatcagc accatttcgc
    33601 cgtcgcagat ggcatccacg tcaacttcta ctgcgtcatc aaggaaatga tccagcaaca
    33661 ctggcgcatc gttagacacg ctaaccgccg tctggaagta gcgacgcagg tcagcttcgt
    33721 catagacgat ttccatcgcc cgaccgccga gaacgtaaga cggacgtacc accagcgggt
    33781 agccaatctc tttcgccttc tctaccgcca tttcaatagc ggtaacggtg gcgttcgccg
    33841 gttgtttcag tttcagacgg tcaactgcat gctggaagcg ttcacggtct tccgcacggt
    33901 cgatagcatc cgggctggtg ccgataaccg gtacgccagc ggcttccagt gcgcgcgcca
    33961 gtttcagcgg ggtctggccg ccgtactgaa cgataacacc tttcggcttc tcaatacgca
    34021 cgatttccag cacatcttcc agagttaccg gctcgaagta gaggcgatcg gaagtgtcgt
    34081 agtcagtgga gacggtttcc gggttacagt taaccataat ggtttcgtaa ccgtcttcgc
    34141 gcagcgccag tgaggcgtgt acgcaacagt agtcgaattc gataccctga ccgatacggt
    34201 tcgggccgcc gccgaggacc atgattttgt cacggtcaga tgggttggat tcgcactctt
    34261 cttcataagt ggagtacata taagcggtgt cggtagcaaa ctctgccgca caggtatcca
    34321 cgcgcttgta aaccgggtgc aggtcatact ggtcacgcag cttacggatt tctgcttcac
    34381 gcacgcccgc gagttttgcc agacgcgcat cggcaaagcc tttgcgtttc agctggcgca
    34441 ggaagtcagc gttcaggcca gtgatgccca cttccgctac tttctcttcc agacgcacca
    34501 gttcttcaat ttgtaccagg aaccagcggt caatgttggt caggttaaag acgccatcta
    34561 cagacaggcc cgcacggaaa gcatcggcga tgtaccagat acgctctgcg cctgcatctt
    34621 tcagttcgcg gcggatttta gtcagcgctt ccgggtcgtc gagactgact ttcgggtcga
    34681 agccagttgc gcccacttcc aggccgcgca gcgctttttg cagggattcc tgctgcgtgc
    34741 gaccaatcgc catcacttcg ccaaccgatt tcatctgagt ggtcagacgg tcgttagcac
    34801 cggcgaattt ctcgaagttg aagcgaggaa ttttagtcac cacgtagtcg atggacggct
    34861 cgaaggaggc cggagtacgg ccaccggtga tgtcgttcat cagctcgtcg agggtgtaac
    34921 ccaccgccag tttcgccgcc actttggcaa tcgggaaacc agtggctttc gacgccagcg
    34981 cagaggagcg agacacgcgt gggttcattt cgataacaat caggcgaccg tttttcgggt
    35041 tcaccgcaaa ttggacgttg gaaccaccgg tttcaacgcc gatttcacgc agtaccgcca
    35101 tcgaggcgtt acgcatgatt tgatattctt tgtcggtcag cgtttgggct ggcgcgacag
    35161 tgatggagtc accggtgtgg atgcccatcg catcaaagtt ttcgatagag cagacgatga
    35221 tgcagttgtc gtttttatca cgcaccactt ccatctcgta ctctttccag ccgatcagcg
    35281 actcatcaat cagcagctct ttagtcggag agagatccag accgcgggcg caaatttctt
    35341 caaactcttc gcggttataa gcgataccgc cgccgctacc acccatggta aaggatgggc
    35401 gaataatgca cgggaagcca acttcagcgg caaccgccag cgcttcttcc attgaatgag
    35461 cgataccgga acgcgcagtt tccagaccga ttttcttcat cgctacgtcg aaacggcggc
    35521 ggtcttcggc tttatcaatc gcatcggcag tggcaccaat catggtgacg ccgaactctt
    35581 ccagcacgcc ctgacgctca agctccagcg cacagttcag cgccgtctgc ccccccatgg
    35641 ttggcagcac cgcgtccggg cgctcttttt caataatctt gcgtaccact tcccagtgaa
    35701 tcggctcgat gtaggttgca tcagccattt ccgggtcggt catgatagtc gccgggttgg
    35761 agttcaccag aatgacgcgg taaccctctt cacgcagggc tttacacgct tgcgcgccag
    35821 agtagtcaaa ctcacacgcc tgaccgataa caatcgggcc cgcacccaga atcaggatac
    35881 tttttatatc tgtacgtttt ggcatggctc ttttactcct gattacttag cggttttacg
    35941 gtactgctca attaacgcga taaagtggtc gaacaacggc gcggcgtcgt gtggaccagg
    36001 gctggcttcc gggtgaccct ggaagctgaa cgccggttta tcggtgcgat gaatgccctg
    36061 taacgtaccg tcgaacaggg atttatgcgt gacacgcagg tttgcaggta atgttgcttc
    36121 gtccaccgca aaaccgtggt tctgggcggt gatcatcacc acgtttttct caacatcttt
    36181 aaccggatgg ttgccgccgt ggtgaccaaa tttcattttg atggtcttcg caccgctcgc
    36241 cagcgccagc agctgatgac cgagacagat gccgaatacc ggaatatcgg tttcgaggaa
    36301 tttctggatg gctgtaatgg cgtaatcgca cggggccggg tcgccaggac cgttggagag
    36361 gaagatgccg tccggattca ttttcagcac atcttccgca gaagtttgtg ccggaacgat
    36421 ggtcagtcga caacctctat ccaccagcat acgcaggatg ttgcgcttgg caccaaaatc
    36481 ataagccacg acgtggaacg gcagctcgtc ttcttttttc gcttctggca ggccgccggt
    36541 cagtgtccag ctcccttgtg tccagctata gggttctgcg gtggttactt cttttgccag
    36601 atccatgccg ttcagacctg ggaacgcacg ggctttttct aacgccagcg ccgcatccgg
    36661 gttgtcaccc gcaataatgc agccattctg agcacctttc tcacgcagta aacgcgtcag
    36721 cttacgggta tcgatatcgg caatcgccac tatgttatgg cgcttcaggt aagaagagag
    36781 gtcttcggta ttacggaagt tgctggcaat cagcggcagg tcgcgaatca ccagaccttg
    36841 ggcatgtacc tgagaagatt cttcatcggc gtcattagtg ccgacattgc caatatgggg
    36901 ataagtaaga gtaacgattt gacgagaata ggaaggatca gtgaggattt cttgataacc
    36961 ggtcattgaa gtattgaaaa cgacttcccc aaccgccgaa cctgttgccc ctatggcccg
    37021 accgtgaaac tgggttccgt cttccagaac caatagcgct gacttaatca aaacaccctc
    37081 cagagaatat tcactcactt tatttgcata ttaattcaca atgatgacgt aaatcaatgc
    37141 aaatctgctt accgacgaat ttctggcaaa cggcggcatt ctggagatat gggcgctaaa
    37201 agtcaactta atggcgggat tttttatatt attttgtggc tcatgcatgt tttacaggca
    37261 ttaagcgaca aaaagatcat ataacatgtt ctggaaaacg cttgcgcagc aagaagattg
    37321 catgaaataa aaatgagcag aaaaaagtgg accagatggt caaaatttac attaaaacaa
    37381 caaaaacaga atacaaaata tgtaattttc agcatttgca ttaaatttaa aatcataaca
    37441 ccaaaaataa aagggccaaa aattaaagcc ctttataatc aataaattga atgtgttatt
    37501 tttgcatcat cataaacatt ttgtggttac aaattattga gatcaagcac atctcgcata
    37561 tcaaaaagac cactttcctt accactcaac cacaaagccg atcttaccgc gccgttagca
    37621 aatgtcatgc ggctggacgc cttatgggtg atctccagac gctcgccaat atcggcaaac
    37681 atcgcggtat gttcgccaac gatgtcacct gcacgcacgg tggcaaaacc aatgctacca
    37741 ggcacacgtt caccggtatg gccttcacga ctgtagaccg cgcaatcttt cagatcttta
    37801 tcaagggcgt gggcgatcgc ctctcccatt gccagtgcgg tgcctgacgg cgcatcaact
    37861 ttatgtctat gatgtgcttc aataatttcg atatcggtgt agtcacccat cactttggct
    37921 gctttctcca gcagcttaag catgacgtta acgccaacgc taaaattggc ggcaaagaca
    37981 atcgcaatat cggcggcggc gtcacgaatc gcctgtttac cggcttcgtc aaaccccgta
    38041 gtgccgatca ccatcccttt gccatgctgg cgacaaaaag cgagatgatt cagcgtacct
    38101 tccggacggg taaaatcgat aaacacatca aaatcatctt ttaccgcatc gaggctactt
    38161 tgcacggtca cgccggtttt cccggctccg gccagttcgc ccgcatcgct gcccagtaaa
    38221 gaagatcctt cgcgctccag cgccgcgccc agctgcacgc cttctaatgc cagcgccgcc
    38281 tgaatcaact ggcggcccat acggcccccg gctcccgcga tggcaacgcg gatgtttgca
    38341 tcatgcatag ctattctctt ttgttaattt gcatagaccg ttttcagagt aaccagcgca
    38401 tcgctacgcc gccagccaaa aacgctgata attagaaatt aatgataaac agggagggat
    38461 atcagtgaaa ggcatgagtc gatgaatgac tgcatgccga taacatgtga caggttacgg
    38521 caccagagcc agcacctcag ctacccactg ctggaagcct tttacattca gatccaatgc
    38581 cacctttaca ttggctggtt tgcccaggca accgtcgata tcaaccaccg tcgtgcctga
    38641 ggtaaattcg ccttgagttt ctaccgcgac aaaacacggc ttgagggtga ataagtccgg
    38701 gcgcaccagc caggcgatgg cgcagagatc gtgcattcgc agtccacttt gcatactgcc
    38761 gctacggtag tggctaaaca gggcgtggag catttttccg gtgcgattca actccggcaa
    38821 agtagcgaga tagtcagggg ttaatattgc ctgattggtg acatccagac cgcacatgac
    38881 gatttcgatg ccgctacgga agacacaggc tgccgcttct ggatcggcag cgatattaaa
    38941 ctcggcgttt ggtgtgcagt tgccgcgacc ggcggaaccg cccatgatca ccagacggcg
    39001 aatatgcggt ttgcattccg ggcattgtga aagtaacagc gcaatattgg ttaacgggcc
    39061 gatggctacc agggtaacag gctcaggcgc acgcagcagg gcatcacgaa tcgccagaaa
    39121 tgcgggtttg tccagtgggc ttctgttgtg ctcaacaaag tcgtagccag ccattcccga
    39181 ttcaccgtgc acagatgctg cattacgcgg tgcgcgtacc agcggcacag cggctccctg
    39241 ggcgagcgga atctccgcat tccagaaatg cagcagttgc agggcgttgc gggtggtttt
    39301 ctcaaccgag acattacccg cgacggtggt catcagttgc aggtcgagtt cgggtgcaaa
    39361 aatcgcggca gcaatggcga cggcatcgtc aatgccgggg tctgtatcga ggaagatagg
    39421 taaacgcatg ttttctccat aaaaaatgcc ggtaacaaga ccggcatttt cgcataactt
    39481 aggctgctaa tgacttaatc gacttcacga atatcgacac gcagctcttt cggcacttcg
    39541 aaaacaatat tttcttcacg gccttccagc ggaatggctt caccaccgcc cagctgttgc
    39601 aaacgtgcca ccacattctg caccagaata tccggagccg atgcgcccgc agtcacgccg
    39661 acgcatttaa cctctttcac ccactcttcc tggatatctt tcgcatcgtc aatcaaaaac
    39721 gcgcgtttgc ccatacgttg ggccagctcc gccagacggt tggagttgga ggagtttttc
    39781 gaaccgacca ccagcacaac ttccgcctgt tctgccaggg cgcgtaccgc ttcctgacgg
    39841 ttagtcgtgg cgtagcagat gtcatctttg cgcggaccga caattttcgg gaagcgttta
    39901 cgcagcgcgt cgatcacatc agacgtgtca tccaccgaca gcgtggtttg ggtcataaag
    39961 gagagcttct cttcgttttt gaccgtcagt ttccacacat cgtctggcga ttcgaccaga
    40021 tacattcccc cttccgggtt gctgtactga cccatcgtcc cttccacttc cgggtgcccg
    40081 gcgtgaccga taagaataga ttcttcgcca cgacggctgg cgcgggcgac ttccatatgc
    40141 actttggtca ccagcggaca ggtggcgtcg aataccgtca aatcgcggct ttttgcttcg
    40201 ttacgtaccg cctgagaaac accgtgtgcg gagaaaatca ggatcgcgcc gtccggtact
    40261 tcgctaatct gctcaataaa gatagcccca cgctcgcgca ggctatcgac cacgtagcgg
    40321 ttatgcacca cttcgtgacg gacatatatc ggtgcgccgt aaatggccag cgcgttttca
    40381 acaatgctga tagcgcggtc taccccggca caaaaaccac gtgggttggc caacaggatc
    40441 tgcatgttac gcctccagtg ccggatcgat ttccagcact tcaatatcaa aatgaacggt
    40501 ctgcccggcc agcggatggt tgaaatcaac ggtaatggag tcgccgttaa tttcgcggat
    40561 cacgccaggc atctcactgc catccattgc ggtaaaaagc atgattgcgc caatttctgg
    40621 ctcgcctgca tccataaact cacggcggga gaagtactga atcaggtccg gtgacggcac
    40681 gccaaacgcc gcatctggct ccagcgagaa agtggtttta tcgcccactt tcagccccag
    40741 caggtgttgc tccagccctt cggaaagaga agcatcgccc aggcggaata gcgccggttt
    40801 accgttgttg cgggtagact cggcggtggt gccatcgtcg agttttagcg tgaaatgcac
    40861 caggacggcg ctattgctct gtacagattc agacatgcag gtttgctctt atattttgag
    40921 gatttttgcc ggatgcggcc tacgatttcg cagcaatctg taggccggat aagatgcgtc
    40981 agcatcgcat ccggcagggt ttattattgt tttttcgctt tagaaggtaa aaaaccttcc
    41041 agcacaatca gtgccgcacc gacacaaatg gcagtatcgg caaggttgaa ggtggcgaag
    41101 tgccagtcgc cgacgtagaa gtcgatcata tcgacaacga agccgtgcca caggcggtcg
    41161 aacaggttgc ccagcgcgcc gccaataatc agcgcgtaag cgatattgtt tagcttctgc
    41221 gtggccttcg agcgatacat catcactgcc aggatcacgc taataccaat cgcaataccg
    41281 gcaaagaacc aacgctgcca gccgccgcta tcggcaagga aactaaacgc cgcgccatag
    41341 ttacgcgcat aatgcagatt aagcgacggg aacagcggga ccgtatcccc cagagcaaag
    41401 ttctggagga tcaggtattt gctgcccaga tcgataatca gcacgactac caccagccac
    41461 agccagcgta gccctgttga acagatcgat tgactcatca ggcaaactta cgtttttcac
    41521 cgtcaccggc gacgttgctg acacagcggt cgcagatttc tgcgtgttcc gccaccttgc
    41581 cgacatcctg ggtgtagtgc cagcagcgtg ggcacttctc accttcggct ttactcaacg
    41641 cgactttcag gcctttgagt acttcgctct gctgagcatc agcaggtgcg tcgttatagt
    41701 ctgcaacggt agcgccggag gtcaacagga caaatcgtaa ttcatcgccc agcgcggtca
    41761 gtttcgccgc cagttccggt tctgcataca aggttactgc cgcttccagc gagccaccca
    41821 ctttcttgtc ggcacgcgct tgctcaatga ctttgttcac ttcgccacgc actttcaaca
    41881 gctcgtccca gaacgcatcg ttcattgctt cactgtctgc cagaccaaac aggccttcgt
    41941 accactcacc ggtgaagacg tatttttcac gttcgcccgg caggtagccc cacacttcat
    42001 cagcggtgaa ggagaggatt ggtgccatcc agcgcaccag cgcttccgcg atgtgataca
    42061 gcgcagtctg gcagctacga cgcgccacac tgtccgcttt ggcggtgtac tgacggtctt
    42121 tgatgatgtc gaggtagaag gaacccatct caacggagca gaagcgcatc tgacgctgta
    42181 ccacctcgtg gaaatcgtat gcttcgtacg ccttgaggat gtcttcctgc gccgctttcg
    42241 cacaacctac ggcccagcga tccagtacca ccatctcttc cggtttcacc atatcttttg
    42301 ccggatcaaa accgttcagg tttgccagca ggaagcgcgc ggtgttacgg atacgacgat
    42361 agctgtcggc agcacgcttc aggatctcgt cagaaacagc catttcgccg gtgtagtcgg
    42421 ttgatgccac ccacagacgc agaatatccg cgcccagttt gttcatcaca tcctgcggcg
    42481 aaacggtgtt gccgatggat ttagacatct tgcggccctg accatccacg gtaaagccgt
    42541 gggtcagtac ctgacgatac ggtgctttgc ccttcatcgc ggtagagatc atcagagagg
    42601 acatgaacca gccacggtgc tggtctgaac cttccagata catgtccgca gcgtgaccgg
    42661 caaattccgg acgcacgtca acaacggaag agtgggtaga tccggagtca aaccatacgt
    42721 cgagagtatc cggcactttc acgtactgat cagcttcatc gccgaggatc tctttcgcat
    42781 cgagatccca ccacgcctgg atgccgtcaa cttcaacgcg tttagccact tcttccatca
    42841 gttcgagggt acgcggatgc agctcttccg tgtctttatg cacgaacagt gacatcggta
    42901 cgccccaggt gcgctgacgg gagatacacc agtcaggacg gttagcaacc atcgactcga
    42961 tacgcgcctg gccccagtcc gggatccact gcacgccttt gatctctttc agtgactgcg
    43021 cacgcagacc tttctgatcc atgctgacga accactgcgg cgtcgcgcgg aagatgatcg
    43081 gcgttttgtg acgccagcag cacggatagc tgtgctgcat tttctcaacg tgcagcagcg
    43141 cgcctttttc ctgcagcagc gcaacgacga tgtcgttcgc tttgaagacg ttcacgccat
    43201 ccagcgtcgg gtaagtgccc ggcagataag tgccgtccgg gccaaccggg ttagcggttt
    43261 ccaggccata tttctgaccg atcacatagt cgtccgggcc gtggccaggc gcggtgtgaa
    43321 cggcaccggt accggcatcc agggtaacgt gatcgccgag gatagcagga acgtcgaagc
    43381 ccataaacgg atgggtaaag cgcagcagct caagctccgc accttttacc gtgccgagaa
    43441 tggtgtaatc ggtcacgccg atacgctgca ttacgctttc aaccagatct ttcgccagaa
    43501 tcacggcctg accgtcgatc tgcaccagcg catagtcgaa atcaggtgca atagagattg
    43561 cgcggttggc aggcagagtc cacggcgtag tggtccagat caccagcgag attgggccgt
    43621 taacgttgct tacgccaaat tttgctttca gtgcatcctg atcgaccgcc tggaaagcaa
    43681 cgtcgatgga cggagaagtt ttgtcgtaat actcaacttc cgcttccgcc agcgcagaac
    43741 ggcagtcaac gcaccagtgt accggcttcg cgcctttgtg caggtgaccg ttgccgatga
    43801 ttttgcccag cgcgcggatg atattagctt cagttttgaa atccatggtc aggtacgggt
    43861 gggaccagtc gcccagcacg cccagacgga taaagtcttt gcgctgaccg tcaacctggg
    43921 tcgccgcgta ttcgcggcac ttggcgcgga actcagcggc ggtgaatttc tcacccggct
    43981 taccgtattc ttgctctact ttcagctcga tcggcagacc gtggcagtcc cagccaggca
    44041 catacggcga gtcataaccg gaaagccctt tggacttcac gataatgtct ttcagaatct
    44101 tgttaaccga gtgaccaata tgaatgctgc cattcgcata aggagggcca tcatgcagaa
    44161 tgaaggtttt tttgcctttt ttagccgcac ggatgatgcc gtacagatca tcatcagtcc
    44221 aacgcgccag cattcccggt tcgcgcttgg cgagatcgcc acgcatcggg aaccctgttt
    44281 ccggcaaatt cagggttgat ttatagtcac tcatcagatt ctcggttccg tgtttcggtt
    44341 tgattacata acaggcttaa gccggttttg ttagcccaaa aaattcgcgg gcggttaatt
    44401 catcacgcgc aatctgcgct ttcagttcgt ccagcgacgc aaatcgctgc tcattgcgta
    44461 tttttttacg cagcactact tgtatatggc gaccgtaaag gtccattgca acatctaaca
    44521 aatgcacttc cagctgctgg cgaataccgg caaccgttgg gcgtgttccg atgtttgcca
    44581 cgccgggtaa cggcttttca ccgaggtcca gcacttctac cgcataaact cctttcaccg
    44641 gggaaacctg acggcgcagc ggtacattcg ccgtcgggaa acctatagtg cgccctaatt
    44701 catcaccgtg gactacacgc ccggagatgg caaacgggtg ccccagtaaa ctttctgcca
    44761 gagccagatt gtcatccgca agggcctgac gcacggcggt gctgctgata cgcacgccac
    44821 cttcgcaaaa agtttgcgta ctggtgatat cgaagccgta ttccatgcca gctttctgta
    44881 ataacaagaa atcgccttca cgaccagcgc caaagcggaa atcatcccct acagcaagaa
    44941 attttacgcg caaatgcttc accagaagat cgctgatgaa attttgcgcg gttaacgccg
    45001 cgaaacgcct gtcgaaacgc acgcacagca cgtaatcaac gccacactct gcaaggtaac
    45061 gcagtttttc ccgcagtcgg gtcagccgtg ccggggcttt atcggtagca aacagttcca
    45121 gtggttgagg ttcaaaaagc atcaccatca ccggtaagtt gcgcttgcgc ccttcttcct
    45181 gcaagccctg taacagcgcg cgatgaccgc gatgcacgcc gtcgaaatta ccaatagtca
    45241 gcacacaccc ttcttgcggg gcctggctga gattatgtat gccgcgtatc agcttcatgt
    45301 ctggctcaaa acagtgaaaa tcgtccgagt ataccttgta cagcggtcaa ggttaaccgg
    45361 cgattgagta ccgaaatcag aaagaagtgg cttttcattg ccatggcgca aatcacggga
    45421 agaaactgac cgcctgctgc aatttttatc gcggaaaagc tgtattcaca ccccgcaagc
    45481 tggtagaatc ctgcgccatc actacgtaac gagtgccggc acattaacgg cgcttatttg
    45541 cacaaatcca ttgacaaaag aaggctaaaa gggcatattc ctcggccttt gaattgtcca
    45601 tatagaacac atttgggagt tggaccttgg ctaatatcaa atcagctaag aagcgcgcca
    45661 ttcagtctga aaaggctcgt aagcacaacg caagccgtcg ctctatgatg cgtactttca
    45721 tcaagaaagt atacgcagct atcgaagctg gcgacaaagc tgctgcacag aaagcattta
    45781 acgaaatgca accgatcgtg gaccgtcagg ctgctaaagg tctgatccac aaaaacaaag
    45841 ctgcacgtca taaggctaac ctgactgcac agatcaacaa actggcttaa tcgccaattt
    45901 gctgaagctt tgtgaaaaag cccgcgcaag cgggtttttt tatgcctgct gcttttgtga
    45961 tgcgtgagaa aacacactgc cggttgccag atagtcaaaa gatgctggtt cttgcagaca
    46021 tgccgttaca ctctctgaac tcttcgtggc ttaaaaatcg tagaatcatc tgctgataca
    46081 ttctgaataa gaatatctac tcaatcttca gactccccct acacagaatg tggagattgt
    46141 gatacacatt gaggcattaa acttaagacc actctatttt tgaattaaat tcctatacac
    46201 tttaacgatt c
//
LOCUS       DAPOAV010000030        46100 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.030, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000030 DAPOAV010000000
VERSION     DAPOAV010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 46100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46100
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.030"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(234..1208)
                     /gene="cysB"
                     /locus_tag="RN951_001920"
     CDS             complement(234..1208)
                     /gene="cysB"
                     /locus_tag="RN951_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012017585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator CysB"
                     /protein_id="HDX2526924.1"
                     /translation="MKLQQLRYIVEVVNHNLNVSSTAEGLYTSQPGISKQVRMLEDEL
                     GIQIFSRSGKHLTQVTPAGQEIIRIAREVLSKVDAIKSVAGEHTWPDKGSLYIATTHT
                     QARYALPNVIKGFIERYPRVSLHMHQGSPTQIADAVSKGNADFAIATEALHLYEDLVM
                     LPCYHWNRAIVVTPDHPLAGKKAITIEELAQYPLVTYTFGFTGRSELDTAFNRAGLTP
                     RIVFTATDADVIKTYVRLGLGVGVIASMAVDPVADPDLVRVDAHDIFSHSTTKIGFRR
                     STFLRSYMYDFIQRFAPHLTRDVVDAAVALRSNEEIEVMFKDIKLPEK"
     gene            complement(1418..4015)
                     /gene="topA"
                     /locus_tag="RN951_001921"
     CDS             complement(1418..4015)
                     /gene="topA"
                     /locus_tag="RN951_001921"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HDX2526925.1"
                     /translation="MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAA
                     KKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEK
                     ADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNID
                     RVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEE
                     FWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPT
                     TSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNM
                     VRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQ
                     LIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRIL
                     PAVNKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRG
                     YVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDH
                     FFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYAL
                     PPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHV
                     CGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTR
                     KILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVE
                     ELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYV
                     DGKWVEGKK"
     gene            4395..4646
                     /locus_tag="RN951_001922"
     CDS             4395..4646
                     /locus_tag="RN951_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciN family protein"
                     /protein_id="HDX2526926.1"
                     /translation="MNKETQPIDRETLLKEANKIIREHEDTLAGIEATGVTQRNGVLV
                     FTGDYFLDEQGLPTAKSTAVFNMFKHLAHVLSEKYHLVD"
     gene            complement(4682..5731)
                     /gene="sohB"
                     /locus_tag="RN951_001923"
     CDS             complement(4682..5731)
                     /gene="sohB"
                     /locus_tag="RN951_001923"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease SohB"
                     /protein_id="HDX2526927.1"
                     /translation="MELLSEYGLFLAKIVTVVLAIAAIAAIIVNVAQRNKRQRGELRV
                     NNLSEQYKEMKEELAAALMDSHQQKQWHKAQKKKHKQEAKAAKAKAKLGEVATDSKPR
                     VWVLDFKGSMDAHEVNSLREEITAVLAAFKPQDQVVLRLESPGGMVHGYGLAASQLQR
                     LRDKNIPLTVTVDKVAASGGYMMACVADKIVSAPFAIVGSIGVVAQMPNFNRFLKSKD
                     IDIELHTAGQYKRTLTLLGENTEEGREKFREELNETHQLFKDFVKRMRPSLDIEQVAT
                     GEHWYGQQAVEKGLVDEINTSDEVILSLMEGREVVNVRYMQRKRLIDRFTGSAAESAD
                     RLLLRWWQRGQKPLM"
     gene            5951..6709
                     /locus_tag="RN951_001924"
     CDS             5951..6709
                     /locus_tag="RN951_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciK family oxidoreductase"
                     /protein_id="HDX2526928.1"
                     /translation="MHYQPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGR
                     NEEKLRQVASHINEETGRQPQWFILDLLTCTSENCQQLAQRIAVNYPRLDGVLHNAGL
                     LGDVCPMSEQNPQVWQDVMQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA
                     NWGAYAASKFATEGMMQVLADEYQQRLRVNCINPGGTRTAMRASAFPTEDPQKLKTPA
                     DIMPLYLWLMGDDSRRKTGMTFDAQPGRKPGISQ"
     gene            6706..7296
                     /gene="cobO"
                     /locus_tag="RN951_001925"
     CDS             6706..7296
                     /gene="cobO"
                     /locus_tag="RN951_001925"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HDX2526929.1"
                     /translation="MSDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTA
                     AFGTATRAVGHGKKVGVVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWDTQNRESDT
                     AACREVWQHAKRMLADSSLDMVLLDELTYMVAYDYLPLEEVVQALNERPHQQTVIITG
                     RGCHRDILELADTVSELRPVKHAFDAGVKAQIGIDY"
     gene            complement(7336..8211)
                     /gene="rluB"
                     /locus_tag="RN951_001926"
     CDS             complement(7336..8211)
                     /gene="rluB"
                     /locus_tag="RN951_001926"
                     /EC_number="5.4.99.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2605) synthase RluB"
                     /protein_id="HDX2526930.1"
                     /translation="MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIAKLGDRVEV
                     TPGLKIRIDGHLISVRESAEQICRVLAYYKPEGELCTRNDPEGRPTVFDRLPKLRGAR
                     WIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDDAKLRDLSRGV
                     QLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDI
                     PLPKGLPRGGWTELDLAQTNYLRELVELPPETSSKVAVEKDRRRMKANQIRRAVKRHS
                     QVSGGRRSGGRNNNG"
     gene            complement(8422..10317)
                     /locus_tag="RN951_001927"
     CDS             complement(8422..10317)
                     /locus_tag="RN951_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HDX2526931.1"
                     /translation="MAGKFRCILLLIAGLFVSSLSYAENTEIPSYEEGISLFDVEATL
                     QPDGVLDIKENIHFQARNQQIKHGFYRDLPRLWMQPDGDAALLNYHIVGVTRDGIPEP
                     WHLDWHIGLMSIVVGDKQRFLPQGDYHYQIHYQVKNAFLREGDSDLLIWNVTGNHWPF
                     EIYKTRFSLQFSNIAGNPFSEIDLFTGEEGDTYRNGRILEDGRIESRDPFYREDFTVL
                     YRWPHALLSNASAPQTTNIFSHLLLPSTSSLLIWFPCLFLVCGWLYLWKRRPQFTPVD
                     VIETDVIPPDYTPGMLRLDAKLVYDDKGFCADIVNLIVKGKIHLEDQSDKNQQILIRV
                     NEGATRNNAVLLPAEQLLLEALFRKGDKVVLTGRRNRVLRRAFLRMQKFYLPRKKSSF
                     YRSDTFLQWGGLAILAVILYGNLSPVGWAGMSLVGDMFIMICWIIPFLFCSLELLFAR
                     DDDKPCVNRVIITLFLPLICSGVAFYSLYINVGDVFFYWYMPAGYFTAVCLTGYLTGM
                     GYIFLPKFTQTGQQRYAHGEAIVNYLARKEAATHSGRRRKGETRKLDYALLGWAISAN
                     LGREWALRIAPSLSSAIRAPEIARNGVLFSLQTHLSCGANTSLLGRSYSGGGAGGGAG
                     GGGGGGW"
     gene            complement(10345..10965)
                     /locus_tag="RN951_001928"
     CDS             complement(10345..10965)
                     /locus_tag="RN951_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HDX2526932.1"
                     /translation="MSQFFYIHPDNPQQRLINQAVEIVRKGGVIVYPTDSGYALGCKI
                     EDKNAMERICRIRQLPDGHNFTLMCRDLSELSTYSFVDNVAFRLMKNNTPGNYTFILK
                     GTKEVPRRLLQEKRKTIGMRVPSNPIAQALLEALGEPMLSTSLMLPGSEFTESDPEEI
                     KDRLEKQVDLIIHGGYLGQKPTTVIDLTDDTPVVVREGVGDVKPFL"
     gene            complement(10962..11843)
                     /gene="yciV"
                     /locus_tag="RN951_001929"
     CDS             complement(10962..11843)
                     /gene="yciV"
                     /locus_tag="RN951_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-3' exoribonuclease"
                     /protein_id="HDX2526933.1"
                     /translation="MSDTNYAVIYDLHSHTTASDGCLTPEALVHRAVEMRVGTLAITD
                     HDTTAAIAPAREEISRSGLALNLIPGVEISTVWENHEIHIVGLNIDITHPLMCEFLAQ
                     QTERRNQRAQLIAERLEKAQIPGALEGAQRLAQGGAVTRGHFARFLVECGKASSMADV
                     FKKYLARGKTGYVPPQWCTIEQAIDVIHHSGGKAVLAHPGRYNLSAKWLKRLVAHFAE
                     HHGDAMEVAQCQQSPNERTQLAALARQHHLWASQGSDFHQPCPWIELGRKLWLPAGVE
                     GVWQLWEQPQNTTEREL"
     gene            11981..12025
                     /gene="trpL"
                     /locus_tag="RN951_001930"
     CDS             11981..12025
                     /gene="trpL"
                     /locus_tag="RN951_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon leader peptide"
                     /protein_id="HDX2526934.1"
                     /translation="MKAIFVLKGWWRTS"
     misc_feature    12002..12095
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00513"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Trp leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00513"
     gene            12117..13679
                     /gene="trpE"
                     /locus_tag="RN951_001931"
     CDS             12117..13679
                     /gene="trpE"
                     /locus_tag="RN951_001931"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HDX2526935.1"
                     /translation="MQTQKPTLELLTCEGAYRDNPTALFHQLCGDRPATLLLESADID
                     SKDDLKSLLLVDSALRITALGDTVTIQALSGNGEALLALLDNALPAGVESEQSPNCRV
                     LRFPPVSPLLDEDARLCSLSVFDAFRLLQNLLNVPKEEREAMFFGGLFSYDLVAGFED
                     LPQLSAENNCPDFCFYLAETLMVIDHQKKSTRIQASLFAPNEEEKQRLTARLNELRQQ
                     LTEAAPPLPVVSVPHMRCECNQSDEEFGGVVRLLQKAIRAGEIFQVVPSRRFSLPCPS
                     PLAAYYVLKKSNPSPYMFFMQDNDFTLFGASPESSLKYDATSRQIEIYPIAGTRPRGR
                     RADGSLDRDLDSRIELEMRTDHKELSEHLMLVDLARNDLARICTPGSRYVADLTKVDR
                     YSYVMHLVSRVVGELRHDLDALHAYRACMNMGTLSGAPKVRAMQLIAEAEGRRRGSYG
                     GAVGYFTAHGDLDTCIVIRSALVENGIATVQAGAGVVLDSVPQSEADETRNKARAVLR
                     AIATAHHAQETF"
     gene            13679..15274
                     /gene="trpD"
                     /locus_tag="RN951_001932"
     CDS             13679..15274
                     /gene="trpD"
                     /locus_tag="RN951_001932"
                     /EC_number="2.4.2.18"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008784940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional anthranilate synthase glutamate
                     amidotransferase component TrpG/anthranilate
                     phosphoribosyltransferase TrpD"
                     /protein_id="HDX2526936.1"
                     /translation="MADILLLDNIDSFTYNLADQLRSNGHNVVIYRNHIPAQTLIERL
                     ATMSNPVLMLSPGPGVPSEAGCMPELLTRLRGKLPIIGICLGHQAIVEAYGGYVGQAG
                     EILHGKASSIEHDGQAMFAGLTNPLPVARYHSLVGSNIPAGLTINAHFNGMVMAVRHD
                     ADRVCGFQFHPESILTTQGARLLEQTLAWAQQKLEPANTLQPILEKLYQAQTLSQQES
                     HQLFSAVVRGELKPEQLAAALVSMKIRGEHPNEIAGAATALLENAAPFPRPDYLFADI
                     VGTGGDGSNSINISTASAFVAAACGLKVAKHGNRSVSSKSGSSDLLAAFGINLDMNAD
                     KSRQALDELGVCFLFAPKYHTGFRHAMPVRQQLKTRTLFNVLGPLINPAHPPLALIGV
                     YSPELVLPIAETLRVLGYQRAAVVHSGGMDEVSLHAPTIVAELHDGEIKSYQLTAEDF
                     GLTPYHQEQLAGGTPEENRDILTRLLQGKGDAAHEAAVAANVAMLMRLHGHEDLQANA
                     QTVLEVLRSGSAYDRVTALAARG"
     gene            15275..16636
                     /gene="trpCF"
                     /locus_tag="RN951_001933"
     CDS             15275..16636
                     /gene="trpCF"
                     /locus_tag="RN951_001933"
                     /EC_number="4.1.1.48"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415778.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional indole-3-glycerol-phosphate
                     synthase TrpC/phosphoribosylanthranilate isomerase TrpF"
                     /protein_id="HDX2526937.1"
                     /translation="MMQTVLAKIVADKAIWVEARKQQQPLASFQNEVQPSTRHFYDAL
                     QGARTAFILECKKASPSKGVIRDDFDPARIAAIYKHYASAISVLTDEKYFQGSFNFLP
                     IVSQIAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDDQYRQLAAVAHSLEMG
                     VLTEVSNEEEQERAIALGAKVVGINNRDLRDLSIDLNRTRELAPKLGHNVTVISESGI
                     NTYAQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVCGLTRGQDAKAAYDAG
                     AIYGGLIFVATSPRCVNVEQAQEVMAAAPLQYVGVFRNHDIADVVDKAKVLSLAAVQL
                     HGNEEQLYIDTLREALPAHVAIWKALSVGETLPAREFQHVDKYVLDNGQGGSGQRFDW
                     SLLNGQSLGNVLLAGGLGADNCVEAAQTGCAGLDFNSAVESQPGIKDARLLASVFQTL
                     RAY"
     gene            16648..17841
                     /gene="trpB"
                     /locus_tag="RN951_001934"
     CDS             16648..17841
                     /gene="trpB"
                     /locus_tag="RN951_001934"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HDX2526938.1"
                     /translation="MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQ
                     FNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG
                     KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH
                     SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILE
                     REGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRV
                     GIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALE
                     AFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILK
                     ARGEI"
     gene            17841..18647
                     /gene="trpA"
                     /locus_tag="RN951_001935"
     CDS             17841..18647
                     /gene="trpA"
                     /locus_tag="RN951_001935"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HDX2526939.1"
                     /translation="MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAG
                     ADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMY
                     ANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADD
                     DLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPD
                     QVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS"
     gene            19028..19207
                     /locus_tag="RN951_001936"
     CDS             19028..19207
                     /locus_tag="RN951_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309858.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HDX2526940.1"
                     /translation="MAEHRGGSGNFAEDREKASDAGRKGGQHSGGNFKNDPQRASEAG
                     KKGGQQSGGNKSGKS"
     gene            19293..19793
                     /locus_tag="RN951_001937"
     CDS             19293..19793
                     /locus_tag="RN951_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HDX2526941.1"
                     /translation="MNMKTIEDVFIHLLSDTYSAEKQLTRALAKLARATSNEKLSQAF
                     HAHLEETHGQIERIDQVVESESNLKIKRMKCVAMEGLIEEANEVIESTEKNEVRDAAL
                     IAAAQKVEHYEIASYGTLATLAEQLGYRKAAKLLKETLEEEKATDIKLTDLAINNVNK
                     KAENKA"
     gene            19839..20345
                     /locus_tag="RN951_001938"
     CDS             19839..20345
                     /locus_tag="RN951_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HDX2526942.1"
                     /translation="MNRIEHYHDWLRDAHAMEKQAESMLESMASRIDNYPELRARIEQ
                     HLSETKNQIVQLETILDRNDISRSVIKDSMSKMAALGQSIGGIFPSDEIVKGSISGYV
                     FEQFEIACYTSLLAAAKNAGDTASIPTIEAILNEEKQMADWLIQNIPQTTEKFLIRSE
                     TDGVEAKK"
     gene            complement(20405..20530)
                     /locus_tag="RN951_001939"
                     /pseudo
     CDS             complement(20405..20530)
                     /locus_tag="RN951_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415772.1"
                     /note="receptor for colicin S4; incomplete; partial in the
                     middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpW"
     gene            complement(20834..21004)
                     /locus_tag="RN951_001940"
     CDS             complement(20834..21004)
                     /locus_tag="RN951_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001710241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526943.1"
                     /translation="MVRLPPVVMSAKSATARTTIAREDAEDHQVKLSAQKLEELLASM
                     VKDEVDRNDGIY"
     gene            complement(21119..21387)
                     /locus_tag="RN951_001941"
                     /pseudo
     CDS             complement(21119..21387)
                     /locus_tag="RN951_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000937495.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
     gene            21444..22112
                     /locus_tag="RN951_001942"
     CDS             21444..22112
                     /locus_tag="RN951_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDX2526944.1"
                     /translation="MVKSMKKNTDDGAKIYTPLTLKLYDWWVLGVSNRLAWGCPTKEH
                     LLPHYLEHVGNNHLDIGVGTGFYLTHVPESSLISLMDLNEASLNAASTRAGESKIKHK
                     ISHDVFEPYPAALHGQFDSISMFYLLHCLPGNISTKSCVIRNAAQALTDDGTLYGATI
                     LGDGVVHNSFGQKLMRIYNQKGIFSNTKDSEEGLTHILSEHFENVKTKVQGTVVMFSA
                     SGKK"
     gene            complement(22167..22751)
                     /locus_tag="RN951_001943"
     CDS             complement(22167..22751)
                     /locus_tag="RN951_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDX2526945.1"
                     /translation="MAFRMSEQARTIKIYNLLAGTNEFIGEGDAYIPPHTGLPANSTD
                     IAPPDIPAGFVAVFNSDEASWHLVEDHRGKTVYDVASGDELFISELGPLPENVTWLSP
                     EGEFQKWNGTAWVKDTEAEKMFRIREAEETKNNLMQVASEHIAPLQDAADLEIATEEE
                     TSLLEAWKKYRVLLNRVDTSTAPDIEWPTNPVRE"
     gene            complement(22751..25726)
                     /locus_tag="RN951_001944"
     CDS             complement(22751..25726)
                     /locus_tag="RN951_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX2526946.1"
                     /translation="MAVLISGVLKDGAGKPIQNCTIQLKARRNSTTVVVNTVASENPD
                     EAGRYTMDVEYGQYSVSLLVEGFPPSHAGIITVYEDSKPGTLNDFLGAMTEDDVRPEA
                     LRRFELMVEEVARNASAVAQNTAAAKKSASDARTSAREAATHATDAAGSARAASTSAG
                     QAASSAQSASSSAGAASTKASEASKSAAAAESSKSAAATSASAAKTSETNAAASQQSA
                     ATSASTATTKASEAATSARDASASKEAAKSSETNAASSASSAASSATAAANSAKAAKT
                     SETNARSSETAAGQSASAAADSKTAAALSASAASTSAGQASASATAAGKSAESAASSA
                     STATTKAGEAAVQASAAARSASAAKTSETNAKASETSAESSKTAAASSASSAASSASS
                     ASASKDEATRQASAAKGSATTASTKATEAAGSATAAAQSKSTAESAATRAETAAKRAE
                     DIASAVALEDASTTKKGIVQLSSATNSTSESLAATPKAVKAAYELANGKYTAQDATTA
                     QKGIVQLSNATNSTSEMLAATPKSVKAAYDLANGKYTAQDATTAQKGIVQLSSATNSA
                     SETLAATPKAVKAANDNANGRVPSARKVNGKALSADITLTPKDIGTLNSTTMSFSGGA
                     GWFKLATVTMPQASSVVSITLIGGAGFNVGSPQQAGISELVLRAGNGNPKGITGALWQ
                     RTSTGFTNFAWVNTSGDTYDIYVAIGNYATGVNIQWDYTSNASVTIHTSPAYSANKPE
                     GLTDGTVYSLYTPSEQFYPPGAPIPWPSDTVPSGYALMQGQTFDKSAYPKLAAAYPSG
                     VIPDMRGWTIKGKPASGRAVLSQEQDGIKSHTHSASASSTDLGTKNTSSFDYGTKSTN
                     NTGAHTHSLSGSTGSAGDHTHGNGIRWPGGGGSALAFYDGGGFTYVQDSQYQVSPGTS
                     SRRSYYQRIQTQSAGAHTHSLSGTAASSGAHAHTVGIGAHTHSVAIGSHGHTITVNAA
                     GNAENTVKNIAFNYIVRLA"
     gene            complement(25791..26390)
                     /locus_tag="RN951_001945"
     CDS             complement(25791..26390)
                     /locus_tag="RN951_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ail/Lom family outer membrane beta-barrel
                     protein"
                     /protein_id="HDX2526947.1"
                     /translation="MRKLCAVILSAVVWLVAAGMPASAAEHQSTLSAGYLQTHTDMPG
                     SDDLNGINVKYRYEFTDTLGLVTSFSYANAKDEQKTHYSDTRWHEDSVRNRWFSVMAG
                     PSVRVNEWFSAYAMAGVTYSRVSTFSGDYLRVTDSKGKTHDVLTGSDDGRHSNTSLAW
                     GAGVQFNPTESVAIDIAYEGSGSGDWRTNSFIVGVGYKF"
     gene            complement(26458..29937)
                     /locus_tag="RN951_001946"
     CDS             complement(26458..29937)
                     /locus_tag="RN951_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HDX2526948.1"
                     /translation="MGKGSSKGHTPREAKDNLKSTQLLSVIDAISEGPVEGPVDGLKS
                     VLLNSTPVLDSEGNTNISGVTVVFRAGEQEQTPPEGFESSGSETVLGTEVKYDTPITR
                     TITSANIDRLRFTFGVQALVETTSKGDRNPSEVRLLVQIQRNGGWVTEKDITIKGKTT
                     SQYLASVVVGNLPPRPFNIRMRRMTPDSTTDQLQNKTLWSSYTEIIDVKQCYPNTALV
                     GVQVDSEQFGSQQVSRNYHLRGRILQVPSNYNPQTRQYSGIWDGTFKPAYSNNMAWCL
                     WDMLTHPRYGMGKRLGAADVDKWALYVIGQYCDQSVPDGFGGTEPRITCNAYLTTQRK
                     AWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDKVWTYNRSNVVMPDDGAPFRYSFSAL
                     KDRHNAVEVNWIDPDNGWETATELVEDTQAIARYGRNVTKMDAFGCTSRGQAHRAGLW
                     LIKTELLETQTVDFSVGAEGLRHVPGDVIEICDDDYAGISIGGRVLAVNSQTRTLTLD
                     REITLPSSGTTLISLVDGQGNPVSVEVQSVTDGVKVKVSRVPDGVAEYSVWGLKLPTL
                     RQRLFRCVSIRENDGGTYAITAVQHVPEKEAIVDNGAHFDGDQSGTVNGVTPPAVQHL
                     TAEVTADSGEYQVLARWDTPKVVKGVSFLLRLTVTADDGSERLVSTARTTETTYRFRQ
                     LALGRYMLTVRAVNAWGQLGDPASVSFRIAAPAAPSRIELTPGYFQITATPHLAVYDP
                     TVQFEFWFSEKRITDIRKVETTARYLGTGLYWIAASINIKPGHDYYFYVRSVNTVGKS
                     AFVEAVGQPSDDASGYLDFFKGEIGKTHLAQELWTQIDNGQLAPDLAEIRTSIKDVSN
                     EITQTVNKKLEDQSAAIQQIQKVQVDTNNNLNSMWAVKLQQMKDGRLYIAGIGAGIEN
                     TPAGMQSQVLLAADRIAMINPANGNTKPMFVGQGDQIFMNDVFLKRLTAPTITSGGNP
                     PAFSLTPDGRLTAKNADISGNVNANSGTLNNVTINENCRVLGKLSANQIEGDLVKTVG
                     KAFPRDSRAPERWPSGTITVRVYDDQPFDRQIVIPAVAFSGAKHEREHTDIYSSCRLI
                     VRKNGAEIYNRTALDNTLIYSGVIDMPAGHGHMTLEFSVSAWLVNNWYPTASISDLLV
                     VVMKKATTGITIS"
     gene            complement(30004..30342)
                     /locus_tag="RN951_001947"
     CDS             complement(30004..30342)
                     /locus_tag="RN951_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001332187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2526949.1"
                     /translation="MNKTILFCTIIALTGCKSLDYVKSGKPVMEGNSLKNIDELSGCI
                     SRQWAGNGTPITSLPIENGVSLLVPQAMGGYDVVLDIKKAGNGSSFTLYERVPALTPK
                     IFADSVNACK"
     gene            complement(30415..31017)
                     /locus_tag="RN951_001948"
     CDS             complement(30415..31017)
                     /locus_tag="RN951_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HDX2526950.1"
                     /translation="MARICLYGDLQRFGRRIDLRVKTGAEAIRALATQLPAFRQKLNE
                     GWYQVRIAGRDAGENELSARLNEPLANGAVIHIVPRLAGAKSGGVFQAVLGAALIATA
                     IWMPGISIAFSNILFSMGAAMTLGGVAQMLAPKPKTPRTQTTDNGKQNTYFSSLDNMV
                     AQGNVLPVLYGEMRVGSRVASQEISTADEGDGGQVVVIGR"
     gene            complement(30954..31697)
                     /locus_tag="RN951_001949"
     CDS             complement(30954..31697)
                     /locus_tag="RN951_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX2526951.1"
                     /translation="MTETESAILAHARRCAPAESCGFVVRAPEGERYFPCVNISGEPE
                     DYFRMAPEDWLQAEMQGEIVALVHSHPGGLPRLSEADRRLQVQSDLPWWLVCRGAIHK
                     FRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGIEMPDFHRGDDWWRHGQNLYLDNLEAT
                     GLYQVPLSAAQPGDVLLCCFGSSVPNHAAIYCGDGELLHHIPEQLSKRERYTDKWQRR
                     THSLWRHQAWHASAFTGIYNDLVAASTFV"
     gene            complement(31702..32400)
                     /locus_tag="RN951_001950"
     CDS             complement(31702..32400)
                     /locus_tag="RN951_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HDX2526952.1"
                     /translation="MQDIRQETLNECTRAEQSASVVLWEIDLTEVGGERYFFCNEQNE
                     KGEPVTWQGRQYQPYPIQGSGFELNGKGTSTRPTLTVSNLYGMVTGMVEDMQSLVGGT
                     VVRRKVYARFLDAVNFVNGNSDADPEQEVISRWRIEQCSELSAVSASFVLSTPTETDG
                     AVFPGRIMLANTCTWTYRGDECGYHGPAVADEYDQPTSDITKDKCSKCLSGCKFRNNV
                     GNFGGFLSINKLSQ"
     gene            complement(32400..32729)
                     /locus_tag="RN951_001951"
     CDS             complement(32400..32729)
                     /locus_tag="RN951_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX2526953.1"
                     /translation="MKTFHWKVKPGMDVASAPSVRKVRFGDGYSQRAPAGLNADLKTY
                     SVTLSVPRWEATALESFLAEHGGWKSFLWTPPYEWRQIKVTCAKWSSRVSMLRVEFSA
                     EFEQVVN"
     gene            complement(32726..35299)
                     /locus_tag="RN951_001952"
     CDS             complement(32726..35299)
                     /locus_tag="RN951_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDX2526954.1"
                     /translation="MSQPVGDLVIDLSLDAVRFDEQMSRVRRHFSGLDTDARKTASAV
                     EQGLSRQALAAQKAGISVGQYKAAMRTLPAQFTDIATQLAGGQNPWLILLQQGGQVKD
                     SFGGMIPMFRGLAGAITLPMVGVTSLAVATGALVYAWYQGDSTLSAFNKTLVLSGNQS
                     GLTADRMLTLSRAGQAAGLTFNQARESLAALVNAGVRGGEQFDAINQSVARFASASGV
                     EVDKVAEAFGKLTTDPTSGLMAMARQFRNVTAEQIAYVAQLQRSGDEAGALQAANDIA
                     TKGFDEQTRRLKENMGTLETWADKTGKAFKSMWDAILDIGRPESSADMLASAQKAFDE
                     ADKKWQWYQSRSQRRGKTSSFRANLQGAWDDRENARLGLAAATLQSDMEKAGELAARD
                     RAEREASQLKYTGEAQKAYERLQTPLDKYTARQKELNKALKDGKILQADYNTLMASAK
                     KDYESTLKKPSGVKVSAGERQEDRAHAAMLALETELRTLEKHSGVNEKISQQRRDLWE
                     AENQYVVLKEAATKRQLSEQEKSLLAHEKETLEYKRQLAELGDKIEHQKRLNELAQQA
                     ARFEQQQSAKQAAISAKARGLTDRQAQRESEEQRLREVYGDNPAALAKATSALKNTWS
                     AEEQLRGSWMAGMKSGWGEWAESATDSFSQVKNAATQTFDGIAQNMAAMLTGSEQNWR
                     GFTRSVLSMLTEIFLKQAMVGIVGSIGSAIGGAFGGGASASTGTAIQAAAANFHFATG
                     GFTGTGGKYEPAGIVHRGEFVFTKEATSRIGVGNLYRLMRGYATGGYVGGTGSPAQMR
                     RSEGIRFEQNNNVVIQNDGTNGLPGPQMLKAVYDMARKGARDEIQAQMRDGGLFSGGG
                     R"
     gene            complement(35280..35693)
                     /locus_tag="RN951_001953"
     CDS             complement(35280..35693)
                     /locus_tag="RN951_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein T"
                     /protein_id="HDX2526955.1"
                     /translation="MGRPDWRAMLAGMTSTEYADWHRFYRTHYFQDTQLDMHFSGLTY
                     AVLSLFFCDPDMHPSDFSLLVPRHEEEQVERPDEDKMLMQKAAGLAGGVRFGGDGGRD
                     ILSSADVADVMVDDAALMMASAGIPGGVRYVPAGW"
     gene            complement(35720..36151)
                     /locus_tag="RN951_001954"
     CDS             complement(35720..36151)
                     /locus_tag="RN951_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein G"
                     /protein_id="HDX2526956.1"
                     /translation="MFLKTEQFEYNGVSVTLSELSALQRIEHLALLKRRAEQAESCGN
                     LQVSVEDLVRTGAFLVAMSLWHNHPQKTQSPSMNEAVMKIEQEVLTTWPADAIARAED
                     VVLCLSGMIEAVRPDTDITEVAKNNTLTDDDFSAGKSSTAS"
     gene            complement(36165..36917)
                     /locus_tag="RN951_001955"
     CDS             complement(36165..36917)
                     /locus_tag="RN951_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX2526957.1"
                     /translation="MATPNPLEPVKGAGTTLWVYNGKGDAYANPLSDDDWQRLAKVKD
                     LTPGEMTAESYDDNYLDDEDADWTATGQGQKSAGDTSFTLAWKPGEEGQKGLIGWFES
                     GDVRAYKIRFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGKPSVAEERSKITP
                     VSAIKVTPTSGTVAKGKTTTLTVSFEPESATDKTFRAVSADPSKATISVKDMTITVNG
                     VATGKVQIPVVSGNGQFAAVAEVTVTEAGAAG"
     gene            complement(36925..37320)
                     /locus_tag="RN951_001956"
     CDS             complement(36925..37320)
                     /locus_tag="RN951_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX2526958.1"
                     /translation="MKHTDIRAAVLDALEQHEHGATLFDGRPVVFDEEDFPAIAVYLT
                     DAEYTGEELDADTWRATLHIEVFLPAQVPDSELDQWMESRIYPAMTAIPALAGLITTM
                     VTQGYEYRRDDDMALWSSADLTYSITYEM"
     gene            complement(37317..37850)
                     /locus_tag="RN951_001957"
     CDS             complement(37317..37850)
                     /locus_tag="RN951_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX2526959.1"
                     /translation="MAIKGLDQAIDNLSRVRKNAIPAASAMAINRVATTAINQSSSQV
                     ARETKVRRKLVKERSRLKRATVRNPNARIIVNRGDLPVIKLGIRMLGRRPNSILKAGQ
                     HRYQRAFIQRLKNGRWHVMQRVAGKNRYPIDVVKIPMAAPLKQAFDENVDRIRRERLP
                     KELAYALKQQLRIAIKR"
     gene            complement(37866..38219)
                     /locus_tag="RN951_001958"
     CDS             complement(37866..38219)
                     /locus_tag="RN951_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001204533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX2526960.1"
                     /translation="MRDFQNAFDAALAGVDSTIVEVMGLCAQFTSGAQCGSEVQGVFD
                     DPESLGFAGGGVRIEGSSPSLFVRTDTVRAVRRGDTLTINGEIFWVDRVSPDDGGSCY
                     LWLNRGQPPAVNRRR"
     gene            complement(38212..38595)
                     /locus_tag="RN951_001959"
     CDS             complement(38212..38595)
                     /locus_tag="RN951_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001355131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein FI"
                     /protein_id="HDX2526961.1"
                     /translation="MATKEENLNRLRQLAGLLGREADMSGSAADIAQRVSEWEEELAV
                     SPEGIMHSDESGADQNHTDDGEQLNNTDAPDDVKAVRVRKCLQVMGYCPETGRPVELA
                     LRGMRVLVPSSLATAMIQHGTAEYA"
     gene            complement(38647..39675)
                     /locus_tag="RN951_001960"
     CDS             complement(38647..39675)
                     /locus_tag="RN951_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HDX2526962.1"
                     /translation="MGLFTTRQLLGYTEQKVKFRALFLELFFRRTVNFHTEEVMLDKI
                     TGKTPVAAYVSPIVEGKVLRHRGGETRVLRPGYVKPKHEFNYQQAVERLPGEDPAQLN
                     DPAYRRLRIITDNLKQEEHAIVQVEEMQAVNAVLYGKYTMEGDQFDTVEVDFGRSEGN
                     NIEQADGKKWSEQDRDTFDPTHDIDLYCDQASGLVNIAIMDGTVWRLLNGFKLFREKL
                     DTRRGSNSQLETAVKDLGAVVSFKGYYGDLAIVVAKTSYVAEDGTEKRYLPEGMLVLG
                     NTAAEGIRCYGAIKDAQALSEGVVASSRYPKHWLTVGDPSCEFTMTQSAPLMVLPDPD
                     EFVVVQVK"
     gene            complement(39733..40080)
                     /locus_tag="RN951_001961"
     CDS             complement(39733..40080)
                     /locus_tag="RN951_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HDX2526963.1"
                     /translation="MVTKTITEQRAEVRIFAGNDPAHTATGSSGISSATPALTPLMLD
                     EATGKLVVWDGQKAGSAVGILVLPLEGTETVLTYYKSGTFATEAIRWPDSVDEHKKAN
                     AFAGTALSHTALP"
     gene            complement(40117..41622)
                     /locus_tag="RN951_001962"
     CDS             complement(40117..41622)
                     /locus_tag="RN951_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S49 family peptidase"
                     /protein_id="HDX2526964.1"
                     /translation="MRRNLSHIIAAAFNEPLLLEPAYARVFFCALGREMGAASLSVPQ
                     QQVQLDAPGMLAETDEYMAGGKRPARVYRVVNGIAVLPVTGTLVHRLGGMRPFSGMTG
                     YDGIVACLQQAMADSQVRGILLDIDSPGGQAAGAFDCADMIYRLRQQKPVWALCNDTA
                     CSAAMLLASACSRRLVTQTSRIGSIGVMMSHVSYAGHLAQAGVDITLIYSGAHKVDGN
                     QFEALPAEVRQDMQQRIDAARRMFAEKVAMFTGLSVDAVTGTEAAVFEGQSGIEAGLA
                     DELINASDAISVMATALNSNVRGGTMPQLTATEAAVQENQRVMGILTCQEAKGREQLA
                     TMLAGQQGMSVEQARAILAAAAPQQPVASAQSEADRIMACEEANGREQLAATLAAMPE
                     MTVEKARPILAAAPLADAGPSLRDQIMALDEAKGAEAQAEKLAACPGMTVENARAVLA
                     AGSGKAEPVSASTTALFEHFMANHSPAAVRGGVSQTSADGDADVKMLMAMP"
     gene            complement(41612..43204)
                     /locus_tag="RN951_001963"
     CDS             complement(41612..43204)
                     /locus_tag="RN951_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDX2526965.1"
                     /translation="MKRTPVLIDVNGVPLRESLSYTGGGAGFGGQMAEWLPPSQSADA
                     ALLPALRLGNARADDLVRNNGIAANAVALHKDHIVGHMFLISYRPNWRWLGMRETAAK
                     SFVDEVEAAWSEYAEGMFGEIDVEGKRTFTEFIREGVGVHAFNGEIFVQPVWDTESTQ
                     LFRTRFKAVSPKRVDTPGHGIGNRFLRAGVEVDRYGRAVAYHICEDDFPRSGSGRWER
                     IPRELPTGRPAMLHIFEPVEDGQTRGANQFYSVMERLKMLDSLQATQLQSAIVKAMYA
                     ATIESDLDTEKAFEYIAGAPQGQKDNPLINILDKFSTWYDTNSVTLGGVKIPHLFPGD
                     DLKLQTAQDSDNGFSALEQALLRYIAAGLGVSYEQLSRDYSKVSYSSARASANESWRY
                     FMGRRKFIASRLATQMFSCWLEEALLRGIIRPPRARFDFYQARSAWSRAEWIGAGRMA
                     IDGLKEVQESVMRIEAGLSTYEKELALMGEDYQDIFRQQVRESAEREKAGLSRPVWIA
                     QAYQQQIAESRRPEEETTPRET"
     gene            complement(43201..43407)
                     /locus_tag="RN951_001964"
     CDS             complement(43201..43407)
                     /locus_tag="RN951_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDX2526966.1"
                     /translation="MVTVAELQALRQARLDLLTGKRVVSVQKDGRRIEYTAASLDELN
                     RAINDAESVLGTTRRRRRPLGVRL"
     gene            complement(43391..45319)
                     /locus_tag="RN951_001965"
     CDS             complement(43391..45319)
                     /locus_tag="RN951_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit family protein"
                     /protein_id="HDX2526967.1"
                     /translation="MISDAQKAANAAGAIATGLLSLIIPVPLTTVQWANKHYYLPKES
                     SYTPGRWETLPFQVGIMNCMGNDLIRTVNLIKSARVGYTKMLLGVEAYFIEHKSRNSL
                     LFQPTDSAAEDFMKSHVEPTIRDVPALLELAPWFGRKHRDNTLTLKRFSSGVGFWCLG
                     GAAAKNYREKSVDVVCYDELSSFEPDVEKEGSPTLLGDKRIEGSVWPKSIRGSTPKIK
                     GSCQIEKAANESAHFMRFYVPCPHCGEEQYLKFGDDASPFGLKWEKNKPESVFYLCEH
                     HGCVIHQSELDQSNGRWICENTGMWTRDGLTFFSAADNEIPPPRSITFHIWTAYSPFT
                     TWVQIVYDWLDALKDPNGLKTFVNTTLGETWEEAVGEKLDHQVLMDKVVRYTAAVPSR
                     VVYLTAGIDSQRNRFEMYVWGWAPGEEAFLVDKIIIMGRPDEEETLLRVDVAINKKYR
                     HADGTEMTISRVCWDTGGIDGEIVYQRSKKHGVFRVLPVKGASVYGKPVITMPKTRNQ
                     RGVYLCEVGTDTAKEILYARMKADPTPADEATSYAIRFPDDPEIFSQTEAQQLVAEEL
                     VEKWEKGKMRLLWDNKKRRNEALDCLVYAYAALRVSVQRWQLDLAVLAKSREEETTRP
                     TLKELAAKLSGGVNGYSR"
     gene            complement(45291..45839)
                     /locus_tag="RN951_001966"
     CDS             complement(45291..45839)
                     /locus_tag="RN951_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HDX2526968.1"
                     /translation="MKVNKKRLAEIFNVDPRTIERWQSQGLPCVSKGSKGIESVFDTA
                     MAIQWYAQRETDIENEKLRKELADLRAAAESDLQPGTIDYERYRLTKAQADAQELKNA
                     REDGVVLETELFTFILQRVAQEISGILVRVPLTLQRKYPDISPSHLDVVKTEIAKASN
                     VAAKAGENVGGWIDDFRRTEGS"
BASE COUNT        10789 a        13055 c        11089 g        11167 t
ORIGIN      
        1 aaaaatccag cgaatttacg aatcgtctcc agtgaataat tcaatctttt gacctgaaat
       61 agatatttga aaactggagt ttgcgaggcg ggtaattaga cactacttta caggtaattt
      121 accctataaa tatgagggat aaaaatattg tgcacggtat agaaataagt aacaaaagag
      181 aatatattcc ggcaccttcg ctacataaaa ggtgccgaaa ataacgcaag aaattatttt
      241 tccggcagtt ttatatcttt aaacatgacc tcaatttctt cattagagcg caatgcgaca
      301 gccgcatcaa cgacatcacg cgttaaatgc ggtgcaaaac gctgaatgaa atcatacata
      361 taactgcgca agaaagtact acggcgaaaa ccaattttgg ttgtactgtg gctgaagata
      421 tcgtgagcat caacacgcac aaggtcggga tcggcgaccg gatccaccgc catgctggca
      481 atgaccccta cccccagccc taaccggacg taagttttaa tgacgtcagc atccgttgcc
      541 gtgaaaacga tacgcggcgt taaccctgcg cgattaaagg cagtatccag ttctgaacgt
      601 ccggtaaagc cgaaggtata tgtcaccaac ggatattgcg ccagttcttc aatggtaatg
      661 gcttttttgc ctgccagcgg gtgatccgga gtgactacaa tagcccgatt ccagtggtag
      721 cacggtaaca tcactaaatc ttcatacaga tgcagcgctt ctgtggcgat agcgaaatca
      781 gcattgcctt tagagacggc atcagcaatt tgtgtcggcg agccctggtg catatgcaaa
      841 gaaacgcgag gataacgctc aataaagcct ttgatgacgt ttggtaatgc gtagcgtgcc
      901 tgggtatgcg tggtggcgat atacagtgaa cctttatccg gccaggtgtg ctctccggca
      961 accgatttta tggcatcgac tttcgacagg acttcgcgag cgatacgaat tatttcttgc
     1021 cctgctggcg ttacctgcgt caggtgcttg ccgcttcggg aaaaaatttg aatgcctagc
     1081 tcgtcttcca gcattctgac ttgtttactg atcccgggtt gtgatgtgta aagtccttcc
     1141 gctgttgatg agacattcag gttatgattg accacctcaa caatatagcg aagttgttgt
     1201 aatttcatgt taaaccatcc acttagacgc catcagaaca tcgttttttc gtcacacctg
     1261 gcgggtgact aatacgattt aataataaaa aaggtgctaa ctataaccac tatatcattt
     1321 atagccttag tgtataggtg tgaagaaaaa ataatatgca ataaaaaagg gccgctttcg
     1381 cgaccctttg tttataaaaa cctgacagaa ttaaaggtta tttttttcct tcaacccatt
     1441 tgccatcaac ataaaatgct gaccagccag tcgcctttcc gtctttttcc gaagagacat
     1501 attgctgttt ggttttacgg ctaaagcgaa ccatggtctt attaccttcc ggatcctgct
     1561 gtggcgcatc ggccagataa cgcagttttt ccggcagacg gtcgcggaag cgataaagct
     1621 cttccaccag tggcgcacgc gtttcacgcg atttcgggaa agtgttggca gccaggaaca
     1681 caccggcagc accgtcacgc agcacgaaat aagcatctga tttttcgcac ggcagctcag
     1741 gtaatggcac cggatcttct ttcggtggtg ccacttcgcc gttacgtaaa atcttacgtg
     1801 tgtttttaca ctcttcgttg gtgcaggcca tgtatttacc gaaacgcccc attttcaggt
     1861 gcatttcaga gccacatttt tcacactcaa cgatcgggcc gtcataacct ttaatgcgga
     1921 attcgccctc ttcgatctcg taaccgtcgc aggttgggtt attaccacag acatgcaact
     1981 tacgtttcgg atcgatgaga tagctgtcca tcgccgtgcc gcatttcggg caacgacgtt
     2041 ttgcgcgcag cgcgttggtt tcagcatctt cgccttccag cacgttcagc acttcgtttt
     2101 ccggcaccag gttaatggtg gttttgcaac gctctttcgg cggcagcgca tagccagaac
     2161 agccaaggaa taccccggtg ctcgctgtgc gaatccccat tttgcgacca caagtcgggc
     2221 agtcaatgct ggtcagaacc atctggttcg ggcgcatacc accctcttcc ggatcttttt
     2281 cagctttatc taactgctgg gtgaaatccg agaagaagtg atccagtaca gctttccact
     2341 ctgcttcgtg atttgccacc tggtcgaggc tgttttccat ctgcgcggta aagtcgtagt
     2401 tcattaactc gcggaaattt tcttcaaggc gatcggtgac gatttcgccc attttttccg
     2461 catagaaacg acgattttct actcgcacgt agccacgatc ctgaatggtc gaaatgatcg
     2521 acgcataggt agacggacga ccgataccgc gtttttccag ctctttaacc agcgatgctt
     2581 cactgaaacg ggctggcggc ttggtaaagt gctgggctgg tgtaagttca acgagcgtca
     2641 gagcatcgcc tttattaact gctggtaaga tgcgatcttc atcgccttta cgcaacgcag
     2701 gcatcacttt tgtccagcca tcaaaacgca aaatacgacc gcgtgctttc aggcggaaat
     2761 cgcccgcacc aacggtcagc gtcgtggagt catatttcgc tggagtcatc tggcaggcaa
     2821 cgaactgacg ccagattaac tggtacagtt tctgcgcatc tgcttccata tccttcagcg
     2881 attccgccat cacattgacg tcagaaggac gaatcgcttc gtgcgcttcc tgtgagtttt
     2941 ctttgctggc gtactgattc ggactttccg gcagatattt cttaccaaaa ttatcgctga
     3001 tataaccgcg aaccatattt accgcgtcct gactcaggtt agtggagtcg gtacgcatgt
     3061 aagtgatata gcctgcttca tacaaacgct gcgccatcat catggttttt ttcacgccaa
     3121 atccaagacg ggtgctggca gcttgttgca gcgtagaggt aataaaagga gcgccaggtt
     3181 tactggttgt cggtttgtct tcacgttcca gcacgctgta gcgcgctttt tccagcagac
     3241 ttaccgcagc ctgagtttgt tctttgttga ccggacggaa cggtttgtcg ttctgatgag
     3301 tcacctgtaa cgccaacgct tcaccagatg gcgtggtcgt gctggcatcg acttcccaga
     3361 actcttccgg cacgaacgct ttaatttcac gctcacgctc gaccaccagg cgaaccgcca
     3421 ccgactgcac acgaccggca gacagaccac gagcgatctt tttccatagc agcggcgaaa
     3481 ccatataccc caccacgcgg tccataaagc gacgcgcctg ctgggcatta acacgatcaa
     3541 tattcagctc acccggtttg ttaaatgcct ggcggatcgc gtttttagta atttcgttaa
     3601 acaccactcg gctatagcgc gcatcatcac ccccaatcac ttcccgcagg tgccatgcaa
     3661 tggcttcccc ttcgcggtca aggtcggttg cgagatagat gtggtcggct ttttcagcca
     3721 gttgtttcag ttcagagacg accttctctt taccaggcaa cacttcatag tgcgcctccc
     3781 aattgtgcca cgggtcaacc cccatacggt tgacgagagc gccacgttca tcctttttag
     3841 gctttttagc cgtcttggtg gaggtagagt cggcactctt tttggcagct gagccactgg
     3901 tcggcaaatc gcggatgtga ccgacgctgg atttcaccac gtagtcacta cccagatact
     3961 tgttgatcgt tttggctttt gccggggact caacgatgac aagagcttta cccatattca
     4021 ccttacctaa tttgattctt ccaggaatgc gtcgcacgtt gataaacctt ccactggcaa
     4081 cgagttaccg atatggactc gctctctgcg gatatcaacc ccttgtcgtg actctgttca
     4141 cgaaaattca ggtgactgag ttaacaggtc ttggcctaca ggcgctatag cacgacggaa
     4201 ttttggtcga atgtcaagca aatctattgc cagattgacg aaagcgtcac actgtacctg
     4261 ataaaatccg atacgcaact ttattagcat gcaaaatcca aagttgccag taaggcgctc
     4321 ttgccaccag cgtggtatat ttgtctgcaa gccatgcctg gcgtagacta atgtccttgt
     4381 ttaaggagta aataatgaac aaagagacac aacccatcga ccgcgaaacg ctgttgaaag
     4441 aggccaacaa aatcattcgt gagcatgagg atacgctcgc agggattgaa gccaccggcg
     4501 tcacgcagcg taatggcgtg ctggtattta ccggcgacta ctttttagat gaacaaggat
     4561 tgccaacagc caaaagcacc gcggtgttta atatgttcaa acacctggcc catgtgcttt
     4621 cagaaaaata tcatctggtt gattaaagca aaacgcgagg tcttagcctc gcgtttgtct
     4681 tttacatcaa tggcttttga ccccgctgcc accagcgtag caacaatcga tcggcgctct
     4741 ctgccgcgct gccggtgaat cggtcaatga gtcgtttacg ctgcatatag cgtacattga
     4801 ccacttcacg gccttccatc aggctaagaa taacttcatc actggtgttg atttcatcaa
     4861 ccaggccttt ctctaccgcc tgttgtccgt accagtgttc acccgttgcc acctgttcaa
     4921 tatccagaga aggacgcata cgcttcacaa aatctttaaa caactgatgc gtttcgttca
     4981 actcttcgcg gaatttctcc cgcccttctt cggtattttc acccagcaac gtcagcgtgc
     5041 gcttatactg cccggcagtg tgcagttcga tatcaatatc tttgcttttc aggaagcggt
     5101 taaagttggg catttgcgcc accacgccaa tggaacccac aatagcaaac ggtgcggaaa
     5161 caattttgtc cgccacacag gccatcatgt aaccgccgct ggcagcgact ttgtctaccg
     5221 taacagttaa aggaatgttt ttatcgcgca gacgctgcag ttgcgaagcc gccagcccgt
     5281 aaccatgcac catgccacca gggctttcca gacggagcac aacctgatcc tgcggtttga
     5341 atgctgcgag tacagccgtt atctcttcac gtagcgagtt cacttcatgg gcgtccatgc
     5401 tgcctttaaa atccagcacc cagacgcggg gtttactgtc agttgccacc tcgcccagtt
     5461 tggctttcgc ttttgctgct ttcgcttctt gcttatgctt tttcttctgc gctttgtgcc
     5521 actgtttttg ctgatgtgag tccatcagcg ccgcggccag ttcttctttc atctccttat
     5581 actgttcgct gagattgttg acccgtaact cgccacgctg gcgtttatta cgttgagcaa
     5641 cattgacaat aatggcggca atcgccgcaa tcgctagcac aacggtaacg attttcgcca
     5701 aaaacaaacc atattcagac aacaattcca cgagtcccca ccttggttaa acaacgcttt
     5761 ggctcacagt ttacaacagg catgttaagc cgtctcgcag agatgttatt gcagcgaaag
     5821 tatgacaaag tatccatttt gcggtgttat cgccccaggc tgattgaaat gcccttctgt
     5881 ttcaggcata aagccccaaa gtcataaagt acactggcag cgcgacagac aacgtcgttg
     5941 aggagtagcc atgcattacc agccaaaaca agatttactc aatgatcgca ttatcctggt
     6001 gacgggagcc agcgatggta ttggtcgtga agccgcgatg acgtatgcac gctatggtgc
     6061 gacagtgatt ctgttgggcc gtaatgaaga aaaattacgt caggtagcca gccacataaa
     6121 cgaagaaact gggcgtcagc cacagtggtt tattctcgat ttgctgacct gcacgtccga
     6181 aaattgccaa caactggcac agcgcattgc cgttaattat ccgcgtctgg atggtgtttt
     6241 gcataatgcc ggattgctcg gcgatgtttg cccaatgagc gaacaaaatc cgcaggtctg
     6301 gcaggacgtc atgcaggtca acgttaatgc cacctttatg ctcacccagg cactgcttcc
     6361 tttattactc aaatcggacg ccggttcact ggtctttact tcatcaagcg ttggacgtca
     6421 gggacgagcc aactggggtg catatgcagc gtcgaaattt gccaccgaag ggatgatgca
     6481 ggtactggcc gatgaatatc agcagcgcct gcgtgtcaac tgcattaacc caggcggtac
     6541 gcgcaccgca atgcgtgcca gcgccttccc gaccgaagat ccacagaaac ttaaaacacc
     6601 cgctgatatc atgccgctct acctctggct gatgggcgat gacagccgcc gtaaaaccgg
     6661 catgaccttt gacgcccaac cgggccgtaa accaggaatt tcccaatgag tgatgaacgc
     6721 taccaacagc gtcagcagcg agtgaaagaa aaagtagatg ctcgtgtggc ccaggcccag
     6781 gatgaacgcg gtattatcat cgtctttacc ggcaatggaa aaggcaaaac caccgcggca
     6841 tttggtacgg caacacgcgc agttggtcac ggaaaaaaag taggcgtcgt gcagtttatt
     6901 aaaggcacct ggcctaatgg cgaacgcaat ctgctggagc cacatggcgt tgagtttcag
     6961 gtgatggcaa cgggctttac ctgggataca caaaaccgcg agtctgatac cgccgcctgc
     7021 cgcgaagtct ggcaacatgc aaagcggatg cttgctgatt cctcactgga tatggttttg
     7081 cttgatgaac tgacgtatat ggtggcgtat gactatttgc cactggaaga agtggtgcag
     7141 gcgttaaatg aacgtccaca tcaacagacg gtgattatca cgggtcgtgg ttgtcatcgg
     7201 gatattcttg aactggcaga tacggtaagt gaattacgcc ccgtcaaaca tgcgtttgat
     7261 gccggtgtaa aagcgcagat agggatcgat tattaatctg taaaaatgcc ggatatgacg
     7321 tccggcatac tttgattaac cgttattatt acgtccgcca gaacgacgac cgccgctcac
     7381 ctgactgtga cgtttcaccg cacgacgaat ctgattcgcc ttcatgcgac gacggtcttt
     7441 ttctacagcg actttagagc tggtttctgg cggtagctcc accagttcgc gcagatagtt
     7501 agtctgggcg aggtccagct ccgtccagcc accgcgtggc agaccttttg gcagtgggat
     7561 atcaccgtaa cgaacacgga tcaggcggct cacctgcaca ccaaccgctt cccacagacg
     7621 acgaacttca cggttacggc cttcggtcag agtcacgttg taccactggt tgatcccttc
     7681 gccgccgctg aacttgatgg ttttaaaagc tgccggacca tcttccaact gcacgccacg
     7741 actcaaatca cgcagtttcg cgtcgtcaac ctgaccaaat acacgcacgg catattcacg
     7801 ttcaacttca cggcttgggt gcattaaacg gtttgccagt tcaccatcgg tggtgaacag
     7861 cagcagacca caggtattaa cgtccaagcg acccacggca atccagcgtg cgccacgcag
     7921 ttttggcaga cggtcaaaca ccgttggacg tccttccgga tcgttacggg tacacaactc
     7981 accttccggt ttgtaatagg ccagaacgcg acaaatttgt tcagcggact cacgtaccga
     8041 aatcaggtga ccatcgatac ggattttcaa tccaggggta acttcaacac gatcgccgag
     8101 tttagcaatt ttgccatcaa cactcacacg accggcttca ataatagatt cgatttcacg
     8161 gcgagaaccg tggccggcac gcgccagcac tttctgtagc ttttcgctca tagagcttcc
     8221 ttttggtgtc gccttcccag gcgtctgata tgcttttgtg caacagtgag tcagaactta
     8281 catctgactc actgatagta aagtctgttt gaactcttca ggccttaagt aaacgactcg
     8341 acgtttatcg gcctggcttt gaggcgcaac atactacact atctttatgg ttaaagcttg
     8401 tttcgattaa catcagctta attaccagcc accaccgcct ccgccacccg cgccgccgcc
     8461 agcaccacca ccggaataac ttcgccccaa caaactggta ttggccccgc aacttaggtg
     8521 cgtctgtaat gagaataaaa cgccgttacg ggcaatctct ggagcgcgaa tcgccgaaga
     8581 aagcgaaggg gcaatgcgta acgcccattc cctccccaaa tttgccgata tagcccaacc
     8641 tagcaacgcg taatccagtt tccgtgtttc ccctttccgc cgacgtccac tgtgtgttgc
     8701 tgcctcttta cgcgcaagat agttaacgat agcttcaccg tgggcataac gttgctgtcc
     8761 agtttgggta aactttggca gaaaaatata ccccatgcca gtgagataac cggtcaggca
     8821 aacagcggta aaataacccg ctggcatata ccagtaaaag aatacatctc cgacattgat
     8881 gtagagagaa tagaaggcca cgcctgaaca aatcagtggt aaaaacaaag tgatgattac
     8941 acgattaacg caaggcttgt catcatcgcg ggcaaacaaa agctcaaggg aacaaaataa
     9001 aaaaggaata atccagcaga tcataataaa catatcgccc accagactca ttcctgccca
     9061 gcctacagga ctcaagttac cgtaaagaat gaccgccaat attgccagtc caccccattg
     9121 caaaaaagta tcagaccggt aaaacgaaga ctttttacgc ggcagataaa atttctgcat
     9181 ccgtaaaaat gccctgcgta agactctgtt gcgtctcccc gtaagaacga ccttatcgcc
     9241 tttacgaaat aacgcttcca gtaataactg ctctgcgggc agtaataccg cattatttct
     9301 ggtcgcgcct tcattaacac gaatcaggat ttgctggttc ttgtcagact gatcttccag
     9361 atgaattttt cctttcacaa tcagatttac gatatcggca caaaaacctt tatcgtcgta
     9421 aactagcttc gcatcgagac gtaacatgcc gggcgtgtaa tctggcggaa tgacatcggt
     9481 ttcaatcaca tctaccggcg taaattgcgg cctgcgcttc cagagatata accatccaca
     9541 aaccaggaac agacacggaa accaaattaa caacgatgac gtggagggta aaagaagatg
     9601 gctgaaaata ttcgtcgttt gcggagccga ggcattgcta agtaaagcgt gaggccagcg
     9661 gtagaggacc gtgaaatctt cacgataaaa cggatcgcgg gattcaattc ttccgtcctc
     9721 aaggatgcgg ccattacgat atgtgtcgcc ctcttctccg gtaaagagat cgatttcgct
     9781 aaatggatta cccgcaatat tagagaactg gagagaaaaa cgggtcttat aaatttcaaa
     9841 cggccagtgg ttaccggtca cgttccagat tagcagatca gaatccccct cacgcaggaa
     9901 agcattttta acctgataat gaatttgata atgatagtcg ccttgaggca agaaacgttg
     9961 tttatcgccc acgacaatac tcattaaccc gatatgccag tcaagatgcc agggttcagg
    10021 aataccatca cgggtgacgc caacaatatg atagttcagc agtgcagcgt ccccatcagg
    10081 ctgcatccat agtcgtggta aatcacgata aaagccgtgc ttaatctgct gatttcgcgc
    10141 ctgaaaatga atattttctt tgatgtcgag caccccatct ggttgcagag tggcttcaac
    10201 atcaaagagc gagatccctt cttcataaga agggatctcc gtgttttctg cataacttag
    10261 agatgataca aacagccctg ctatcaacag caaaatgcag cgaaacttcc ctgccatagt
    10321 cttccatccg tggaacgcaa tttgttataa gaaaggcttc acatcaccta cgccttcacg
    10381 caccacgacc ggcgtatcat cggtaagatc aataaccgtt gtcggtttct gcccgagata
    10441 gccgccgtga ataatcaaat ctacctgttt ttccagacga tctttaattt cttccgggtc
    10501 cgattcggta aattcgctgc ctggcagcat tagcgaagtg gaaagcatcg gttcgcccaa
    10561 tgcttcaagt aacgcctgag cgatagggtt agaaggcaca cgcataccga tggttttgcg
    10621 tttttcctgc aacagacggc gtggcacttc cttcgtcccc ttcaggatga aggtatagtt
    10681 gcccggcgtg ttgtttttca ttaaacgaaa cgcaacgtta tcaacaaatg aataggtcga
    10741 gagttcagaa agatcgcgac acatcagggt aaagttgtga ccgtccggca gctggcgaat
    10801 acgacaaata cgctccatcg cgtttttatc ttcaatttta cagccgagcg catagccgga
    10861 atcagttgga taaacaatca ccccgccttt acgcacgatc tccaccgcct ggttgatcag
    10921 acgttgctgt gggttatcag gatgaatata aaaaaactgg ctcataattc cctctctgtg
    10981 gtgttctgcg gctgttccca tagctgccag acgccttcaa cgcctgcggg cagccagagt
    11041 ttacgaccca gttcgatcca cgggcatggc tgatgaaaat cagatccttg tgatgcccat
    11101 aaatgatgct gacgcgcaag ggccgccagc tgggtacgtt cattgggcga ttgctggcac
    11161 tgcgcgactt ccatcgcgtc accgtggtgt tcggcaaaat gcgcaaccaa tcttttcagc
    11221 catttagcac taagattgta ccgcccagga tgagctagca ccgccttacc gccagaatga
    11281 tgaatgacat caatagcttg ttctattgta caccactgtg gcggaacgta tccggttttc
    11341 ccgcgcgcca gatacttttt aaagacatcc gccattgaac tggctttgcc gcactcaaca
    11401 aggaaacgcg caaaatgacc gcgcgtcact gcgccgccct gcgccagtcg ttgtgcgcct
    11461 tccagcgccc caggtatttg cgctttttca agtctttcgg caatcagctg cgcccgctga
    11521 ttgcgccgtt ctgtctgctg cgcgaggaac tcacacatta gcggatgagt aatatcaata
    11581 ttcagcccga caatatgaat ttcatgattt tcccagaccg tggaaatttc cacgccggga
    11641 ataagattca acgccagtcc cgaacgtgaa atttcctctc ttgctggcgc gattgcagct
    11701 gtggtgtcat ggtcggtgat cgccagggtg ccgacgcgca tctcgactgc acggtgcacc
    11761 aatgcttctg gcgtcaggca gccatcggaa gctgtggtat ggctgtgcag gtcgtaaatc
    11821 actgcataat tcgtgtcgct caaggcgcac tcccgttctg gataatgttt tttgcgccga
    11881 catcataacg gttctggcaa atattctgaa atgagctgtt gacaattaat catcgaacta
    11941 gttaactagt acgcaagttc acgtaagaag ggtatcgaca atgaaagcaa ttttcgtact
    12001 gaaaggttgg tggcgcactt cctgaaacgg gcagtgtatt caccatgcgt aaagcaatca
    12061 gatacccagc ccgcctaatg agcgggcttt tttttgaaca aaattagaga ataacaatgc
    12121 aaacacaaaa accgactctc gaactgctaa cctgcgaagg cgcttatcgc gacaatccca
    12181 ccgcgctttt tcaccagttg tgtggggatc gtccggcaac gctgctgctg gaatccgcag
    12241 atatcgacag caaagatgat ttaaaaagcc tgctgctggt agacagtgcg ctgcgcatta
    12301 cagctttagg tgacactgtc acaatccagg cactttccgg caacggcgaa gccctgctgg
    12361 cactactgga taacgccctg cctgcgggtg tggaaagtga acaatcacca aactgccgtg
    12421 tgctgcgctt cccccctgtc agtccactgc tggatgaaga cgcccgctta tgctcccttt
    12481 cggtttttga cgctttccgt ttattgcaga atctgttgaa tgtaccgaag gaagaacgag
    12541 aagccatgtt cttcggcggc ctgttctctt atgaccttgt ggcgggattt gaagatttac
    12601 cgcaactgtc agcggaaaat aactgccctg atttctgttt ttatctcgct gaaacgctga
    12661 tggtgattga ccatcagaaa aaaagcaccc gtattcaggc cagcctgttt gctccgaatg
    12721 aagaagaaaa acaacgtctc actgctcgcc tgaacgaact acgtcagcaa ctgaccgaag
    12781 ccgcgccgcc gctgccagtg gtttccgtgc cgcatatgcg ttgtgaatgt aatcagagcg
    12841 atgaagagtt cggtggcgta gtgcgtttgt tgcaaaaagc gattcgcgct ggagaaattt
    12901 tccaggtggt gccatctcgc cgtttctctc tgccctgccc gtcaccgctg gcggcctatt
    12961 acgtgctgaa aaagagtaat cccagcccgt acatgttttt tatgcaggat aatgatttca
    13021 ccctatttgg cgcgtcgccg gaaagctcgc tcaagtatga tgccaccagc cgccagattg
    13081 agatctaccc gattgccgga acacgcccac gcggtcgtcg cgccgatggt tcactggaca
    13141 gagatctcga cagccgtatt gaactggaaa tgcgtaccga tcataaagag ctgtctgaac
    13201 atctgatgct ggttgatctc gcccgtaatg atctggcacg catttgcacc cccggcagcc
    13261 gctacgtcgc cgatctcacc aaagttgacc gttattccta tgtgatgcac ctcgtctctc
    13321 gcgtagtcgg cgaactgcgt cacgatcttg acgccctgca cgcttatcgc gcctgtatga
    13381 atatggggac gttaagcggt gcgccgaaag tacgcgctat gcagttaatt gccgaggcgg
    13441 aaggtcgtcg ccgcggcagc tacggcggcg cggtaggtta tttcaccgcg catggcgatc
    13501 tcgacacctg cattgtgatc cgctcggcgc tggtggaaaa cggtatcgcc accgtgcaag
    13561 cgggtgctgg tgtagtcctt gattctgttc cgcagtcgga agccgacgaa acccgtaaca
    13621 aagcccgcgc tgtactgcgc gctattgcca ccgcgcatca tgcacaggag actttctgat
    13681 ggctgacatt ctgctgctcg ataatatcga ctcttttacg tacaacctgg cagatcagtt
    13741 gcgcagcaat gggcataacg tggtgattta ccgcaaccat attccggcgc aaaccttaat
    13801 tgaacgcctg gcgaccatga gcaatccggt gctgatgctt tctcctggcc ccggtgtgcc
    13861 gagcgaagcc ggttgtatgc cggaactcct cacccgcttg cgtggcaagc tgcccattat
    13921 tggcatttgc ctcggacatc aggcgattgt cgaagcttac gggggctatg tcggtcaggc
    13981 gggcgaaatt ctccacggta aagcctccag cattgaacat gacggtcagg cgatgtttgc
    14041 cggattaaca aacccgctgc cggtggcgcg ttatcactcg ctggttggca gtaacattcc
    14101 ggccggttta accatcaacg cccattttaa tggcatggtg atggcagtac gtcacgatgc
    14161 ggatcgcgtt tgtggattcc agttccatcc ggaatccatt ctcaccaccc agggcgctcg
    14221 cctgctggaa caaacgctgg cctgggcgca gcagaaacta gagccagcca acacgctgca
    14281 accgattctg gaaaaactgt atcaggcgca gacgcttagc caacaagaaa gccaccagct
    14341 gttttcagcg gtggtgcgtg gcgagctgaa gccggaacaa ctggcggcgg cgctggtgag
    14401 catgaaaatt cgcggtgagc acccgaacga gatcgccggg gcagcaaccg cgctactgga
    14461 aaacgcagcg ccgttcccgc gcccggatta tctgtttgct gatatcgtcg gtactggcgg
    14521 tgacggcagc aacagtatca atatttctac cgccagtgcg tttgtcgccg cggcctgtgg
    14581 gctgaaagtg gcgaaacacg gcaaccgtag cgtctccagt aaatctggtt cgtccgatct
    14641 gctggcggcg ttcggtatta atcttgatat gaacgccgat aaatcgcgcc aggcgctgga
    14701 tgagttaggt gtatgtttcc tctttgcgcc gaagtatcac accggattcc gccacgcgat
    14761 gccggttcgc cagcaactga aaacccgcac cctgttcaat gtgctggggc cattgattaa
    14821 cccggcgcat ccgccgctgg cgttaattgg tgtttatagt ccggaactgg tgctgccgat
    14881 tgccgaaacc ttgcgcgtgc tggggtatca acgcgcggcg gtggtgcaca gcggcgggat
    14941 ggatgaagtt tcattacacg cgccgacaat cgttgccgaa ctgcatgacg gcgaaattaa
    15001 aagctatcag ctcaccgcag aagactttgg cctgacaccc taccaccagg agcaactggc
    15061 aggcggaaca ccggaagaaa accgtgacat tttaacacgt ttgttacaag gtaaaggcga
    15121 cgccgcccat gaagcagccg tcgctgcgaa cgtcgccatg ttaatgcgcc tgcatggcca
    15181 tgaagatctg caagccaatg cgcaaaccgt tcttgaggta ctgcgcagtg gttccgctta
    15241 cgacagagtc accgcactgg cggcacgagg gtaaatgatg caaaccgttt tagcgaaaat
    15301 cgtcgcagac aaggcgattt gggtagaagc ccgcaaacag cagcaaccgc tggccagttt
    15361 tcagaatgag gttcagccga gcacgcgaca tttttatgat gcgctacagg gtgcgcgcac
    15421 ggcgtttatt ctggagtgca agaaagcgtc gccgtcaaaa ggcgtgatcc gtgatgattt
    15481 cgatccagca cgcattgccg ccatttataa acattacgct tcggcaattt cggtgctgac
    15541 tgatgagaaa tattttcagg ggagctttaa tttcctcccc atcgtcagcc aaatcgcccc
    15601 gcagccgatt ttatgtaaag acttcattat cgacccttac cagatctatc tggcgcgcta
    15661 ttaccaggcc gatgcctgct tattaatgct ttcagtactg gatgacgacc aatatcgcca
    15721 gcttgccgcc gtcgctcaca gtctggagat gggggtgctg accgaagtca gtaatgaaga
    15781 ggaacaggag cgcgccattg cattgggagc aaaggtcgtt ggcatcaaca accgcgatct
    15841 gcgtgatttg tcgattgatc tcaaccgtac ccgcgagctt gcgccgaaac tggggcacaa
    15901 cgtgacggta atcagcgaat ccggcatcaa tacttacgct caggtgcgcg agttaagcca
    15961 cttcgctaac ggttttctga ttggttcggc gttgatggcc catgacgatt tgcacgccgc
    16021 cgtgcgccgg gtgttgctgg gtgagaataa agtatgtggc ctgacgcgtg ggcaagatgc
    16081 taaagcagct tatgacgcgg gcgcgattta cggtgggttg atttttgttg cgacatcacc
    16141 gcgttgcgtc aacgttgaac aggcgcagga agtgatggct gcggcaccgt tgcagtatgt
    16201 tggcgtgttc cgcaatcacg atattgccga tgtggtggac aaagctaagg tgttatcgct
    16261 ggcggcagtg caactgcatg gtaatgaaga acagctgtat atcgatacgc tgcgtgaagc
    16321 tctgccagca catgttgcca tctggaaagc attaagcgtc ggtgaaaccc tgcccgcccg
    16381 cgagtttcag cacgttgata aatatgtttt agacaacggc cagggtggaa gcgggcaacg
    16441 ttttgactgg tcactattaa atggtcaatc gcttggcaac gttctgctgg cggggggctt
    16501 aggcgcagat aactgcgtgg aagcggcaca aaccggctgc gccggacttg attttaattc
    16561 tgctgtagag tcgcaaccgg gcatcaaaga cgcacgtctt ttggcctcgg ttttccagac
    16621 gctgcgcgca tattaaggaa aggaacaatg acaacattac ttaaccccta ttttggtgag
    16681 tttggcggca tgtacgtgcc acaaatcctg atgcctgctc tgcgccagct ggaagaagct
    16741 tttgtcagtg cgcaaaaaga tcctgaattt caggctcagt tcaacgacct gctgaaaaac
    16801 tatgccgggc gtccaaccgc gctgaccaaa tgccagaaca ttacagccgg gacgaacacc
    16861 acgctgtatc tcaagcgtga agatttgctg cacggcggcg cgcataaaac taaccaggtg
    16921 ctggggcagg cgttgctggc gaagcggatg ggtaaaaccg aaatcatcgc cgaaaccggt
    16981 gccggtcagc atggcgtggc gtcggccctt gccagcgccc tgctcggcct gaaatgccgt
    17041 atttatatgg gtgccaaaga cgttgaacgc cagtcgccta acgtttttcg tatgcgctta
    17101 atgggtgcgg aagtgatccc ggtgcatagc ggttccgcga cgctgaaaga tgcctgtaac
    17161 gaggcgctgc gcgactggtc cggtagttac gaaaccgcgc actatatgct gggcaccgca
    17221 gctggcccgc atccttatcc gaccattgtg cgtgagtttc agcggatgat tggcgaagaa
    17281 accaaagcgc agattctgga aagagaaggt cgcctgccgg atgccgttat cgcctgtgtt
    17341 ggcggcggtt cgaatgccat cggcatgttt gctgatttca tcaatgaaac caacgtcggc
    17401 ctgattggtg tggagccagg tggtcacggt atcgaaactg gcgagcacgg cgcaccgcta
    17461 aaacatggtc gcgtgggtat ctatttcggt atgaaagcgc cgatgatgca aaccgaagac
    17521 gggcagattg aagaatctta ctccatctcc gccggactgg atttcccgtc tgtcggccca
    17581 caacacgcgt atcttaacag cactggacgc gctgattacg tgtctattac cgatgatgaa
    17641 gcccttgaag ccttcaaaac gctgtgcctg cacgaaggga tcatcccggc gctggaatcc
    17701 tcccacgccc tggcccatgc gttgaaaatg atgcgcgaaa acccggataa agagcagcta
    17761 ctggtggtta acctttccgg tcgcggcgat aaagacatct tcaccgttca cgatattttg
    17821 aaagcacgag gggaaatctg atggaacgct acgaatctct gtttgcccag ttgaaggagc
    17881 gcaaagaagg cgcattcgtt cctttcgtca cgctcggtga tccgggcatt gagcagtcat
    17941 tgaaaattat cgatacgcta attgaagccg gtgctgacgc gctggagtta ggtatcccct
    18001 tctccgaccc actggcggat ggcccgacga ttcaaaacgc cactctgcgc gcctttgcgg
    18061 caggtgtgac tccggcacaa tgttttgaaa tgctggcact gattcgccag aaacacccga
    18121 ccattcccat tggcctgttg atgtatgcca atctggtgtt taacaaaggc attgatgagt
    18181 tttatgccca gtgcgaaaaa gtcggcgtcg attcggtgct ggttgccgat gtgccagttg
    18241 aagagtccgc gcccttccgc caggccgcgt tgcgtcataa tgtcgcacct atcttcatct
    18301 gcccgccaaa tgccgatgac gacctgctgc gccagatagc ctcttacggt cgtggttaca
    18361 cctatttgct gtcacgagca ggcgtgaccg gcgcagaaaa ccgcgccgcg ttacccctca
    18421 atcatctggt tgcgaagctg aaagagtaca acgctgcacc tccattgcag ggatttggta
    18481 tttccgcccc ggatcaggta aaagcagcga ttgatgcagg agctgcgggc gcgatttctg
    18541 gttcggccat tgttaaaatc atcgagcaac atattaatga gccagagaaa atgctggcgg
    18601 cactgaaagt ttttgtacaa ccgatgaaag cggcgacgcg cagttaatcc cacagccgcc
    18661 agttccgctg gcggcatttt aactttcttt aatgaagccg gaaaaatcct aaattcattt
    18721 aatatttatc tttttaccgt ttcgcttacc ccggtcgaac gtcaacttac gtcatttttc
    18781 cgcccaacag taatataatc aaacaaatta atcccgcaac ataacaccag taaaatcaat
    18841 aattttctct aagtcactta ttcctcaggt aattgttaat atatccagaa tgttcctcaa
    18901 aatatatttt ccctctatct tctcgttgcg cttaatttga ctaattctca ttagcgacta
    18961 attttaatga gtgtcgacac acaacactca tattaatgaa acaatgcaac gcaacgggag
    19021 aaataacatg gccgaacatc gtggtggttc aggaaatttc gccgaagacc gtgagaaggc
    19081 atccgacgca ggccgtaaag gcggtcagca tagcggcggt aattttaaaa atgatccgca
    19141 acgcgcatct gaagcgggta aaaaaggcgg tcaacaaagc ggtggtaata aatcaggcaa
    19201 atcctgattc accgttaatt attaatatca gctgataaag ataattgcat ctgcgggccg
    19261 tatggctcgc agtgatttca ctggagaaaa atatgaatat gaagaccatt gaagatgtat
    19321 ttattcacct gctttcagat acctacagcg cagaaaaaca attaacccgg gcactggcaa
    19381 aactcgcaag agcaacatca aatgaaaaat taagtcaggc ttttcatgcg cacctcgagg
    19441 aaactcatgg acagattgaa cgtattgatc aagttgtgga gtccgaatcg aacctgaaaa
    19501 ttaagcgcat gaaatgtgtg gcaatggaag gtcttattga agaagctaat gaggtcatcg
    19561 aaagtaccga gaaaaacgaa gtgcgtgatg ccgcactgat tgccgcagca cagaaagtcg
    19621 agcattatga gattgccagt tacgggacat tagcgacgct agctgaacaa ttaggttacc
    19681 gtaaagcagc gaagcttctg aaagaaaccc tggaagaaga aaaggccacc gacatcaaac
    19741 tgactgatct ggccattaat aacgtaaata agaaagccga aaataaagcc tgaaatatga
    19801 attttaactt ttagtcattt tataaagagg acattttcat gaatcgtatt gaacattatc
    19861 atgactggtt acgtgacgcc cacgcaatgg aaaagcaagc cgaatctatg cttgaatcca
    19921 tggccagccg tatagataat tatcctgaac tacgcgctcg tattgaacaa catcttagtg
    19981 aaaccaaaaa ccagattgtt caactggaaa ctattcttga tcgtaatgac atttcacgtt
    20041 cagtcattaa agattccatg agtaaaatgg ctgcgcttgg gcagtcaatc ggtggtatat
    20101 tcccttctga tgaaatagtc aaaggctcta ttagcggata tgtcttcgag caatttgaaa
    20161 tcgcctgtta cacctcacta ttagcagcag caaaaaatgc cggtgataca gcttcaattc
    20221 caaccatcga agcgatttta aatgaggaaa agcaaatggc cgactggctg attcagaata
    20281 ttccgcaaac aactgagaaa tttttaattc gctctgaaac tgatggcgta gaagcgaaga
    20341 aataataccc tttataccat gtccttattg accccgtata ttacggggtc gtttttgtgc
    20401 ggaattaaaa acgatatcct gctgagaaca taaacaccca cggatcgagg cgtacgctat
    20461 cgtgttgctg tgcaccgccc agcttataat tggcggtggt atcgatatcc atgtaccaca
    20521 ctggtaggtt tcaaaaaaca caataaccaa ttgtatttga agcaaaaaac aagactttga
    20581 gatgtttttt tgtacctttt ttttatgttt ttaactgtct gattttattg aaatcttttt
    20641 tagttttgca gaaggaattt tttacttgat tgtaactttt tcgttttttt ggggctaatt
    20701 gacgcgcaat gctgggcggg gagcgcacag ccaaaaaaac cgaaattgac cgctaattac
    20761 tgccaatcat catcgctctg attgagcgta aatcattcag gttattcagt tcttccttct
    20821 gctctcgctg acgtcaataa atcccatcat tgcgatcaac ctcatcctta accattgatg
    20881 cgagcagttc ttccagtttc tgcgctgata gctttacctg gtgatcttca gcatcttccc
    20941 gggctattgt ggttcgcgca gtggctgatt ttgctgacat caccacaggg ggcagacgga
    21001 ccattgaacc atggcctccg gaacaaataa gggcaaaaat aacaaccact atcgaaagct
    21061 cacaaactaa ccgcagcacg ttcctgcata cgacgtgtct gcggcataat cccaatgatt
    21121 actccctgac aggatttgca ggccactcaa tatcggtgca gttgatgtat caacacgatt
    21181 caacaatacc cgatatttat tccatgcctc cagcaacgat ctttcttcct ccgttgcgat
    21241 ttccagatct acagcatcct gcagtggcgc aatatactca ctgaattcct ggatgtagaa
    21301 ctgtgtggtg acggtcttcc agccattcgt ctcctgctgt atcgaagcat accaggctat
    21361 ttcaatatcg ctatgctgcg gcagcattta accccttgta attcatcgcc ataattgatt
    21421 taattcacaa ataaaactat aacatggtga aatcaatgaa aaaaaacaca gatgatgggg
    21481 ctaaaattta cacaccactt accctaaagc tttatgactg gtgggttttg ggagtatcaa
    21541 atcggcttgc atggggatgt cctacaaagg aacaccttct tccacactat ctggaacatg
    21601 taggtaacaa ccatctggat attggtgttg gaactgggtt ttaccttact cacgtacctg
    21661 agagtagtct gatatcttta atggatttga acgaagctag cctgaacgcg gcatctacaa
    21721 gggctgggga atcaaaaatt aaacataaaa ttagccatga tgtttttgaa ccttatcccg
    21781 cggcgttaca tggtcaattt gattccattt ccatgtttta ccttcttcac tgcctgcctg
    21841 gaaatatatc tacaaaaagc tgtgtaatac gcaatgcggc gcaggcctta actgacgatg
    21901 gaactctata cggagccaca attcttggcg atggagttgt gcacaatagc ttcggtcaaa
    21961 aactgatgcg catttacaat cagaaaggca tcttttcaaa cacaaaagat tccgaagaag
    22021 gcttaacaca tatactctca gagcatttcg agaatgttaa aaccaaggtt caaggtactg
    22081 tagtaatgtt ttccgcttca gggaaaaaat agcatccaac cgcagcacgt tcttgcttaa
    22141 gacgtgctgc ggcataatcc caatgattac tccctgacag ggttcgtagg ccactcaata
    22201 tcaggtgcag ttgatgtatc aacacggttc agcaacaccc gatacttttt ccaggcttcc
    22261 agcaatgagg tttcttcctc cgttgcaatt tccagatctg cagcatcctg aagcggcgca
    22321 atatgctcac tggctacctg catcaggttg ttttttgttt cttccgcctc ccggatccgg
    22381 aacatttttt ctgcttccgt atccttcacc caggctgtgc cgttccactt ctgaaactcc
    22441 ccttccggcg ataaccaggt aacattttcc ggtaacggac cgagttcaga aataaataac
    22501 tcgtcccctg acgctacgtc ataaaccgtt ttaccccgat ggtcttcaac gagatgccac
    22561 gatgcctcat cactgttgaa aacagccaca aagccagcag gaatatctgg tggtgcaata
    22621 tcggtactgt ttgctggcag acctgtatga ggcggaatat atgcgtcacc ttcaccaata
    22681 aattcattag ttccggccag cagattataa atttttatgg tccgtgcttg ttcactcatt
    22741 ctgaatgcca ttatgcaagc ctcacaatat agttaaatgc gatgtttttg acggtgtttt
    22801 ccgcgttacc agcagcgtta acggtgatgg tgtgtccatg tgaaccaatc gcaacggagt
    22861 gcgtatgcgc accaatacct acagtatgtg catgtgcgcc agaacttgct gcagtaccag
    22921 acagcgagtg ggtatgagca cctgctgact gtgtctgaat acgttgataa tacgatctac
    22981 gggaagaagt ccccgggctt acttgatact gtgaatcctg gacataagtg aacccaccgc
    23041 catcataaaa tgctaacgca gaaccgccgc ctcctggcca acgaatacca ttaccatgag
    23101 tatgatcacc ggcagacccc gtagagccac tcagactgtg cgtatgcgcc ccggtgttat
    23161 tcgtggattt ggttccgtaa tcaaacgacg atgtgttttt cgtccccaaa tccgtactgg
    23221 atgcgctggc gctgtgggtg tgcgatttaa tgccgtcctg ttcctgagac aatacggcac
    23281 gaccactggc gggtttgccc ttaatcgtcc agccacgcat atcagggatc acgcctgacg
    23341 gataagcggc tgcaagtttc gggtatgcag atttgtcaaa agtctgcccc tgcatcaggg
    23401 catagccaga cggaacggta tctgatggcc acgggattgg tgcgccaggc ggataaaact
    23461 gctctgatgg cgtatagagt gaataaactg taccgtccgt taacccttcc ggcttattag
    23521 cagaatatgc tggtgacgta tgaatcgtca cgctggcatt actggtataa tcccattgaa
    23581 tatttacacc agtcgcataa tttccgattg caacgtaaat atcgtaagta tcaccagatg
    23641 tattgaccca ggcaaaattt gtaaaccctg tcgatgtgcg ctgccataaa gcaccagtaa
    23701 tccccttcgg attaccatta cctgcacgca aaacaagttc agatatacct gcctgttgag
    23761 gtgaccccac gttaaatccc gcaccaccaa tcaacgtaat tgaaacaaca gaactcgcct
    23821 gtggcatggt taccgttgct aatttgaacc aaccagcacc accgctgaat gacattgttg
    23881 ttgagttaag cgtaccaata tctttcggcg tcagtgttat atccgctgaa agcgccttac
    23941 cattcacctt acgggcagaa ggtacccgac cattcgcatt atcattagct gctttcactg
    24001 ctttcggtgt cgcggcaagc gtttcagatg cgctgttggt tgcactactg agctggacaa
    24061 ttcctttttg tgctgtcgta gcgtcctgag cagtatattt cccgttagca aggtcatagg
    24121 ctgcctttac cgactttggc gttgccgcca gcatttcaga tgtgctgttg gtcgcgttgc
    24181 taagctgaac tatccctttc tgtgctgtcg ttgcatcctg tgcggtgtat ttcccgttag
    24241 ccagctcata cgcggcctta acggcttttg gcgttgccgc cagtgactcg gaagtgctgt
    24301 tagtcgcact gctgagctgt actatcccct ttttcgtcgt gctcgcatcc tcaagcgcca
    24361 cggcggatgc aatatcctct gcccgttttg ccgctgtctc agcgcgcgtt gccgcggatt
    24421 ccgccgtact tttgctctga gctgccgccg tcgcactgcc agctgcctct gtcgccttcg
    24481 tggatgccgt cgtggcgctg ccctttgctg ctgacgcctg tctggtcgcc tcatcttttg
    24541 aagcagacgc agatgatgcc gatgacgccg ccgaactggc ggacgatgcg gcagccgttt
    24601 ttgaggattc tgcgctggtt tccgacgctt tcgcgttcgt ctcggatgtc ttcgctgcgg
    24661 aagcagacct cgctgctgcg ctggcctgta cagcggcttc gccagccttc gttgtggctg
    24721 ttgaagcaga cgatgcagca ctttctgccg attttccggc ggcggtggca ctggctgagg
    24781 cctgcccggc acttgttgac gcggcactgg cagataatgc agccgctgtt tttgagtctg
    24841 ccgcagctga ggcgctctgt cccgctgccg tttcagaaga cctggcgttc gtctcggacg
    24901 tttttgccgc cttcgcagaa tttgctgccg ccgttgccga ggaagctgcg ctgctggcgc
    24961 tcgaggctgc gttcgtttct gatgattttg ccgcctcttt tgaagccgac gcatcccgtg
    25021 ctgaagtggc tgcttctgac gctttcgtgg tcgcggtgga tgcagaagtg gctgctgatt
    25081 gttgtgacgc tgccgcattc gtttctgacg ttttcgcggc actggcactg gtagctgccg
    25141 cgctttttga ggactctgca gcagcagcac ttttcgatgc ttcactggcc tttgttgatg
    25201 ccgctcctgc gctggaagac gctgactgag ccgacgacgc ggcctgtccg gctgacgtgc
    25261 tggctgcgcg tgctgagcct gcagcatcag tcgcatgggt tgccgcctca cgggctgatg
    25321 tgcgggcatc gctggctgac ttcttcgcgg ctgccgtgtt ctgtgccact gcggacgcgt
    25381 tacgcgccac ctcttccacc atcagttcaa aacggcgcag tgcctctggc cggacatcat
    25441 cctccgtcat tgcaccgagg aaatcattca gtgtgcccgg ctttgagtcc tcatatacgg
    25501 tgataatccc ggcgtgtgac ggcgggaatc cctccaccaa cagactgacg ctgtactgac
    25561 catactcgac gtccattgta taacgcccgg cttcatccgg attttctgag gccactgtgt
    25621 tcaccaccac cgtggtgctg ttgcgcctgg cctttagctg aatggtgcag ttttgtatcg
    25681 gcttacctgc accatctttc agtacacctg aaatcagtac tgccatattc cccccacaaa
    25741 aaagcccgcc tgaaccggcg ggctgtcata acactgtgtt acctggctaa tcagaattta
    25801 tagccgacac caacgatgaa actgttggta cgccagtcac cactgccgga gccttcataa
    25861 gcaatatcaa tggccacgga ttcggtcggg ttaaactgca cgccagcccc ccacgccaga
    25921 gacgtgttgc tgtggcgacc gtcatcactt ccggtcagca catcgtgcgt tttccccttg
    25981 ctgtcagtta cacggagata atccccggaa aaagtcgaca cacgactgta agtcacaccc
    26041 gccatcgcat acgcgctgaa ccattcattc acgcgcacag acggccccgc catcacgctg
    26101 aaccagcggt tacgcacgga atcttcatgc cagcgggtat cgctgtaatg cgttttttgc
    26161 tcatctttgg cattggcata actgaatgac gtcaccagcc ccagcgtgtc cgtaaactca
    26221 taacggtatt tcacgttaat cccgttcaga tcatcgctgc ctggcatatc agtatgggtc
    26281 tgaagatacc cggcgcttag tgtggactga tgctctgctg cgctcgctgg cataccagcg
    26341 gcaaccagcc agactactgc ggacagaata acagcacata atttacgcat aattacctct
    26401 cgcttttctg caataaaaaa ggcaccattt ctggtgcccg tatctgggtt ataaaattca
    26461 gctaatcgtg atgcctgtag tggctttctt catcaccaca accagcaaat cgctgatact
    26521 tgctgtggga taccagttat ttaccagcca tgctgacacc gaaaactcca gtgtcatgtg
    26581 accgtgaccg gcaggcatat caataacgcc actgtaaatc agcgtattat ccagcgcggt
    26641 acggttataa atttcagcac cgtttttccg cactatcaga cggcatgagg agtaaatatc
    26701 agtatgctct ctctcatgct tagcgccact gaatgccacc gccggaataa caatttgccg
    26761 gtcaaacggc tgatcgtcat aaaccctgac ggtaatggtc cctgatggcc accgctccgg
    26821 tgcacgggag tcccggggga aagctttgcc cactgtttta acgagatcgc cttcaatctg
    26881 gttggcggac agttttccca gaacccgaca gttctcgtta atcgtgacgt tgttgagcgt
    26941 cccggagttc gcattcacgt taccgctaat atcggcattt ttcgccgtca gccgcccgtc
    27001 cggtgtcagg gaaaatgccg gaggattacc gccgctggta atggtgggag ccgtcaggcg
    27061 tttcaggaac acgtcgttca tgaatatctg atcgccctga ccaacaaaca tcggctttgt
    27121 gttgccattc gcaggattaa tcatcgcaat cctgtctgcc gccagcagca cctgactctg
    27181 cattcctgct ggcgtattct caataccggc accgataccc gcaatataaa ggcgtccgtc
    27241 cttcatctgt tgcagcttca cagcccacat gctgttcaga ttattatttg tatcaacctg
    27301 aaccttctgt atctgctgaa ttgccgcact ctggtcttcc agtttcttat tgacggtctg
    27361 cgtgatttca ttgctgacat ccttaatgga cgtcctgatt tcagccaggt caggcgcaag
    27421 ctgaccgtta tcaatctgcg tccacagctc ctgagccaga tgggttttcc ctatctcgcc
    27481 tttgaaaaaa tccagataac cggatgcatc atcactcggc tgaccaacag cctccacgaa
    27541 tgccgatttg ccaacggtgt tcacactgcg aacgtaaaaa taataatcat ggcccggttt
    27601 gatattgata ctggcggcta tccagtacag ccccgtgcca agatagcgcg ctgtggtttc
    27661 aaccttcctg atatcggtaa tccgcttttc cgaaaaccag aactcaaact gtaccgtcgg
    27721 gtcataaacg gcaagatgcg gcgtggcggt tatctgaaaa tagcccggcg tcagctcaat
    27781 ccgcgacggc gctgccggtg cggcaatccg gaacgatacc gacgccggat cgcccagctg
    27841 tccccacgca tttaccgccc ggaccgtcaa catgtaacgc cccagcgcca gctgcctgaa
    27901 gcggtatgtg gtttccgtcg tccgggccgt gctgaccagc cgctcactgc catcgtccgc
    27961 tgtcacggtc aggcgaagca ggaagctcac gcccttcacc accttcggcg tgtcccagcg
    28021 ggccagtacc tgatactccc cgctgtctgc ggtgacttcg gcagtcaggt gctgcaccgc
    28081 tggcggcgtg acaccattca ccgtgccgct ctggtcgccg tcaaagtgcg ccccgttatc
    28141 cacgatggct tctttttccg gtacatgctg cacggcggtg atggcatacg tgccgccatc
    28201 gttctcacgg atactcacgc agcggaacag gcgctggcgc agcgtcggca gcttcagccc
    28261 ccacacgctg tattcggcaa cgccgtcagg aacacggctc actttcacct tcacgccgtc
    28321 ggtgacggac tggacctcca cgctgaccgg attcccctgt ccgtcaacca ggcttatcag
    28381 cgtggtgccg gaggatggca gcgtgatttc acggtcgagc gtcagtgtcc gcgtctggct
    28441 gttcaccgcc agcacgcgcc cgccgatgct gataccggca tagtcatcat cacagatttc
    28501 aatgacatcg cccggtacat ggcgaagccc ttctgcaccc acgctgaagt ccacggtctg
    28561 cgtttccagc agctccgttt taatcagcca cagcccggcg cggtgtgcct gcccccggct
    28621 ggtacagcca aaggcatcca tcttcgtgac gttacgaccg taacgggcaa tggcctgcgt
    28681 atcttcaaca agctctgtcg ccgtctccca gccgttatcc gggtcaatcc agttcacctc
    28741 aacggcatta tggcggtcct tcagggcgct gaagctgtag cggaacggcg cgccatcatc
    28801 cggcatcacc acattactgc ggttataggt ccacacctta tccgacggtc ggtcctgcac
    28861 gaacgtcagc gtctgcccgt tccataccgg catacagcgc atcgccgaac agaaatcact
    28921 gagcacatcc cacgccttac gctgtgtggt caggtaagcg ttacaggtga tgcgcggctc
    28981 cgtgccacca aagccatccg gcactgactg gtcgcagtac tggccgatga catacagcgc
    29041 ccatttgtcc acatccgccg caccaagacg tttccccatg ccgtagcgtg gatgggtcag
    29101 catatcccac agacaccagg ccatgttatt gctgtatgct ggcttaaacg ttccgtccca
    29161 gataccgctg tattgccgag tctgcgggtt atagttcgac ggcacctgca gaatacgccc
    29221 gcgcagatga taattacggc tcacctgctg gctgccgaac tgctccgaat ccacctgtac
    29281 gccgaccagt gccgtgttcg ggtagcactg tttcacatcg atgatttcgg tgtatgacga
    29341 ccagagcgtt ttgttctgca gctggtctgt ggtgctgtcc ggcgtcatcc tgcgcatccg
    29401 gatattgaac gggcgcggcg gcaggttacc caccaccacc gatgctagat actgtgaggt
    29461 ggttttgcct ttaatggtga tgtctttttc cgtcacccag ccaccattac gctgtatctg
    29521 aaccagcagg cggacttccg acggattccg gtcccccttt gaggtggttt ccaccagtgc
    29581 ctgcacaccg aaggtaaagc gcagacggtc gatgtttgcc gacgtgatgg tccgggtaat
    29641 cggcgtgtcg tacttcactt ccgtacccag caccgtctcg gagccggagg attcaaatcc
    29701 ctccggcggt gtctgctcct gctcaccggc ccggaacacc accgtgacgc cggatatatt
    29761 ggtattcccc tcactgtcca gcaccggcgt actgttcagc agcacgcttt ttaatccatc
    29821 caccggacct tcaaccggcc cttcgctgat ggcatcgatc acactcagca gctgcgtgga
    29881 cttcaggttg tccttcgctt cgcgcggggt atgcccctta ctgcttcctt tacccattcc
    29941 tcacactcca taaacaacaa agccgcccaa aaggcggctc atgagttacg gcaggattaa
    30001 ctattattta catgcattaa cactatcagc aaaaattttt ggcgttaatg ctggtacacg
    30061 ttcataaaga gtaaaactac tgccatttcc tgcttttttg atatcaagca caacatcata
    30121 tccccccata gcctgtggaa ctaaaaggct taccccattc tcaataggaa gggatgttat
    30181 aggtgttcca ttaccagccc attgtctgga tatgcagcct gacaattcat caatattttt
    30241 taatgaatta ccttccatta caggttttcc ggattttacg taatccaaag atttacatcc
    30301 tgttaaggca ataatcgtgc agaataaaat cgttttgttc atatagctaa ccaatagaat
    30361 aattatcagt gttcgatata aatattaaat cagttagaac atgagtaaat aatattaccg
    30421 cccaattacc acaacctgac caccatcccc ttcatctgcc gtgctgatct cctgagatgc
    30481 cacacgtgac cccacgcgca tttcaccgta cagaacaggc aggacattgc cctgggcaac
    30541 catgttatcc agtgaggaga aataggtgtt ctgtttgccg ttatccgttg tctgtgtacg
    30601 tggagttttg ggtttagggg ccagcatctg tgcgacacca ccaagcgtca tcgctgcccc
    30661 catagaaaag agaatgttac tgaaagcgat actgattcct ggcatccaga ttgccgtagc
    30721 aatcagcgcc gcacccagca ctgcctgaaa aacaccacca cttttggcac ccgccagacg
    30781 cggtacgatg tggatcacgg caccatttgc cagcggctca ttaagacggg cagataattc
    30841 gttttcgcct gcatcacgcc cggcaatgcg cacctgatac cagccctcat tcagtttctg
    30901 gcgaaacgcc gggagctgtg tggccagcgc ccggatggct tcggcccccg ttttcacacg
    30961 aaggtcgatg cggcgaccaa atcgttgtaa atccccgtaa aggcagatgc gtgccatgcc
    31021 tggtgacgcc agagggagtg tgtgcgtcgc tgccatttgt cggtgtacct ctctcgtttg
    31081 ctcagttgtt caggaatatg gtgcagcagc tcgccgtcac cacagtaaat ggcggcatga
    31141 ttcggcaccg atgaaccaaa acagcacagc agcacatcgc ccggctgcgc cgctgacaac
    31201 ggcacctgat acagccctgt ggcctccaga ttatccagat agagattctg accgtgacgc
    31261 caccagtcat ccccgcgatg aaaatccggc atctcaatcc ccgccagatg ataagcatcc
    31321 cggaacagcg tgtaacagtc cgtcaccccg tgctcaaagc gccgcccggt gagatgcggc
    31381 acacagcgga acttgtgaat cgccccccgg cagaccagcc accacggcaa atcactctgc
    31441 acctgcagcc gccggtcagc ctcactcagc ctgggcagac caccgggatg actgtggacc
    31501 agtgccacaa tctcaccctg catctctgcc tgcagccagt cctccggagc catccggaaa
    31561 taatcctccg gctcaccgga aatattcacg cagggaaaat atctttcccc ctccggcgct
    31621 ctcaccacga agccgcacga ctccgctggc gcacatcgcc gggcgtgcgc cagaatcgct
    31681 gattctgtct ctgtcatggg attactgcga aagtttgtta atggaaagga agccgccaaa
    31741 gttgccgacg ttattgcgaa acttacagcc gctcaggcat ttgctgcatt tatccttcgt
    31801 gatatcggac gtcggctggt catattcatc cgcgactgcc ggaccgtgat aaccgcactc
    31861 atcaccgcga taggtccagg tgcaggtgtt ggccagcatg atacgtcccg gaaaaacagc
    31921 gccatccgtt tccgtcggcg tggacagtac aaaggaggca ctcaccgcgc tcagttcgct
    31981 gcactgctcg atgcgccagc ggctgatcac ctcctgctcc ggatcggcgt cactgtttcc
    32041 gttgacgaag ttcaccgcat ccagaaaacg ggcgtaaacc ttacgccgga ccaccgttcc
    32101 gccgaccaga ctctgcatat cttccaccat accggtgacc ataccgtaca ggttagaaac
    32161 cgtcagcgtg gggcgcgtac tggtgccttt gccattcagt tcaaaaccac tcccctgaat
    32221 gggatacggc tgatactgtc gcccctgcca ggtgaccggc tcaccttttt cgttctgctc
    32281 attacagaaa aaataacgtt ctccaccgac ctctgtcaga tcgatttccc agagcaccac
    32341 gctggccgac tgctccgcac gggtgcattc attcagtgtt tcctgccgga tatcctgcat
    32401 cagttcacca cctgttcaaa ctctgcgctg aactcaacac gcagcatact gacccgcgac
    32461 gaccattttg cgcaggtcac ctttatctgc cgccactcat aaggcggcgt ccacagaaag
    32521 gatttccagc ccccgtgctc agccagaaac gactcaagcg ccgtggcctc ccaacgggga
    32581 acagaaagcg tcacgctgta cgttttcagg tcggcattca gcccggcagg cgctcgctgg
    32641 gaatagccat caccaaagcg cactttcctg acggaagggg ctgaagccac atccataccg
    32701 ggtttcactt tccagtggaa ggtcttcatc gtccacctcc ggagaacaga ccaccatcgc
    32761 gcatctgtgc ctgaatttca tcacgggcac ccttgcgggc catgtcatac actgccttca
    32821 gcatctgtgg acctggcaga ccattcgtac cgtcgttctg aatcaccacg ttgttgttct
    32881 gctcaaatct gataccctct gaacgccgca tttgcgccgg acttccggtg ccaccgacat
    32941 aaccgccggt ggcatagccg cgcatcagcc ggtaaagatt tcccacgcca atccggctgg
    33001 tcgcctcctt cgtgaagaca aactccccgc gatgaacaat ccccgcaggt tcatatttcc
    33061 cccccgtccc cgtaaatccc ccggtcgcga aatggaagtt cgccgccgca gcctgaatgg
    33121 ccgtccccgt ggaggcagac gcaccaccac cgaaagcacc gccaatggcg ctgccgatac
    33181 tcccgactat ccccaccatc gcctgcttca gaaaaatctc tgtcagcatg gacagcacag
    33241 aacgggtgaa accacgccag ttctgttcgc tgccggtcag catcgccgcc atattctgtg
    33301 caataccgtc aaaggtctgc gtggccgcgt ttttaacctg cgaaaaactg tccgtcgcac
    33361 tttccgccca ctcgccccag ccggacttca tcccggccat ccagcttcca cgaagctgct
    33421 cctccgcaga ccaggtgttc ttcagtgcag atgtggcctt cgccagcgca gccggattat
    33481 caccgtacac ctcacgaagg cgctgctctt ccgactcccg ctgcgcctga cggtcagtga
    33541 ggccgcgggc ttttgcgctg attgccgcct gcttcgcgct ctgctgctgt tcaaaccgcg
    33601 ccgcctgctg tgccagctca ttcagccgct tctggtgttc aatcttgtct cccagctcag
    33661 ccagctggcg tttgtactcc agcgtctctt tctcatgagc cagcagggat ttttcctgct
    33721 cagataactg ccgtttcgtg gcggcctctt tcaggaccac atactgattt tccgcttccc
    33781 ataaatcccg gcgctgctgg ctgattttct cattcacacc gctgtgtttt tccagcgtcc
    33841 tgagctcggt ttcaagcgcc agcatggctg catgcgcccg gtcttcctgg cgctcaccgg
    33901 cagacacctt cacacctgac ggctttttca gcgtcgattc ataatccttt tttgccgacg
    33961 ccatcagcgt gttgtaatcc gcctgcagga tttttccgtc tttcagggcc ttattcagct
    34021 ctttctgacg ggcggtatat ttatccagcg gcgtctgcag gcgctcatac gccttctgcg
    34081 cctctccggt atacttcagc tgtgacgcct cacgctcagc ccggtccctt gccgccagtt
    34141 caccggcttt ttccatatcc gactgcagcg tggccgctgc cagacccaga cgggcatttt
    34201 cccggtcatc ccatgccccc tgaaggttcg cacgaaaaga ggaggtcttt ccccggcgct
    34261 ggctccgact ctggtaccac tgccattttt tatccgcctc atcaaatgcc ttctgcgcac
    34321 tggcgagcat atccgctgag gattcaggac gaccgatatc cagaatggca tcccacatcg
    34381 atttgaatgc cttccctgtt ttatccgccc aggtctccag tgttcccatg ttttctttca
    34441 ggcgacgggt ctgctcatca aagcctttcg tggcgatatc gttcgccgcc tgcaatgccc
    34501 cggcctcgtc tccggaacgc tgcagctgtg caacatacgc aatctgctct gccgtcacgt
    34561 tacggaactg gcgcgccatc gccatcagtc ccgacgtcgg gtcagtggtc agcttcccga
    34621 aggcttcagc gactttatcc acctccacac cggatgcaga cgcaaaacgc gcgacactct
    34681 ggttgatggc atcaaactgt tcaccaccac gcacaccggc attcaccagg gctgccagtg
    34741 actctctcgc ctggttaaac gtcagccctg ctgcctgccc ggctcttgag agagtcagca
    34801 tacgatcggc agtcagtccg gactgattac cggaaagaac cagggtttta ttaaacgctg
    34861 aaagcgtgga atctccctgg taccaggcgt acaccagcgc acctgtcgcc accgccagcg
    34921 aggtgacccc gaccatcggc agggtgatcg caccggcaag ccccctgaac atggggatca
    34981 tcccgccgaa ggagtccttc acctgaccgc cctgttgcag caggatcagc cagggattct
    35041 gaccacctgc aagctgcgtg gcgatatccg taaactgtgc gggcagggtt cgcatggccg
    35101 ctttatactg cccgacggaa atcccggctt tttgtgcagc cagcgcctgg cggctcaggc
    35161 cctgttcaac agcactggcg gtttttctgg cgtcggtatc cagacctgaa aaatgacgcc
    35221 ttacccggct catctgctca tcgaaacgga cagcatccag actcaggtca ataacaagat
    35281 caccaaccgg ctgggacata tctcacacct cccggaatcc ccgctgaagc catcattaat
    35341 gcggcatcat ccaccatgac atccgccaca tccgcagacg ataaaatatc gcgccctccg
    35401 tccccaccga accggacgcc tccggcaagt cctgccgctt tctgcatcag cattttgtcc
    35461 tcatccggcc tctccacctg ctcttcctca tgccggggga caagcagact gaaatcagag
    35521 ggatgcatat ccggatcgca aaaaaacagg ctgagtacag cgtacgtcag cccggaaaaa
    35581 tgcatatcca gctgggtatc ctgaaaataa tgcgtgcggt aaaaacggtg ccagtcggca
    35641 tattcggtgg atgtcatccc ggcaagcatg gcgcgccagt cgggtctccc catctcacgc
    35701 gccagtctga gggcaaagtt cagctcgccg tcgaagactt tcccgcagaa aaatcatcat
    35761 cagtcagcgt gttatttttc gccacttcag taatatcagt atccggacga acagcttcga
    35821 tcatcccgga caggcacaac accacgtctt ccgcccgggc aatggcatcg gcaggccagg
    35881 tggtgagcac ttcctgctct atcttcatca cggcctcatt cattgacggt gactgcgttt
    35941 tctgtggatg gttatgccac agggacatcg ccaccagaaa cgcgccggtt ctgacgagat
    36001 cttccacgct tacctgcagg ttgccgcagg attctgcctg ttctgcacgc cgtttcagga
    36061 gggcaagatg ctcgatacgc tgcagcgcag acaattcgga aagcgtgaca gacacaccgt
    36121 tatattcaaa ttgttctgtt ttcagaaaca tgtattacct ccgtttaccc tgcagcgccc
    36181 gcttcagtaa cggtgacttc agccactgcg gcgaactgac catttccgct caccacaggg
    36241 atctgcacct tacctgtcgc cacgccgttt accgtaattg tcatatcttt cacactaatg
    36301 gtggctttcg acggatcggc ggaaaccgct ctgaacgtct tgtcggttgc actttccggc
    36361 tcaaaagaaa ccgtcagggt ggttgttttc ccttttgcca ccgtaccgga tgtcggcgtc
    36421 accttaatcg cactgaccgg cgtaattttg ctgcgttctt ccgctacaga aggtttaccc
    36481 acgttagtga ctttcaccgt gcgggtgatc acttctttcg ccgtcacggc cttaccgata
    36541 ctgctgaccc agccacgaaa cacatccacc gtgccattcg gaaaacggat tttataggcc
    36601 cggacatcgc cgctttcaaa ccagcctata agccctttct ggccttcctc tcccggtttc
    36661 caggccagcg taaaactggt atcacctgca gatttctgcc cctgcccggt cgcggtccag
    36721 tccgcgtctt catcatccag gtagttatca tcgtaggatt ctgccgtcat ctcgcccggc
    36781 gtcagatcct tcaccttagc cagtcgctgc cagtcatcgt ctgacaacgg gtttgcataa
    36841 gcatcaccct tgccgttgta aacccacaga gtggtaccgg caccttttac cggctcaagg
    36901 ggatttggtg ttgccatatc gtcctcacat ctcgtatgta atggaataag tcagatctgc
    36961 agaactccat aacgccatat cgtcatcacg acgatactca tagccctgcg taaccatcgt
    37021 ggtaatcagt cctgccagtg ccgggatcgc ggtcatcgcc gggtaaatcc ggctttccat
    37081 ccactgatca agctctgaat ccggtacctg tgccggtaaa aacacctcaa tatgcagcgt
    37141 ggcccgccag gtatctgcat ccagctcttc accggtatac tctgcatccg tcagataaac
    37201 cgcgatcgca ggaaaatcct cttcgtcaaa aacaacgggg cgaccatcaa acagcgtcgc
    37261 cccgtgttca tgctgctcga gtgcatccag cactgcggca cgaatgtcag tgtgtttcat
    37321 cgttttattg caatcctcag ttgttgtttc agcgcgtatg ccagttcttt aggcaggcgt
    37381 tcacgccgga tacggtcaac attctcatca aatgcctgtt tcagtggggc cgccatcggg
    37441 attttcacca catcaatggg gtaacggttt ttcccggcca cacgctgcat gacatgccag
    37501 cgaccatttt ttaatcgctg aataaatgcc cgctgatacc gatgctgacc ggctttaagt
    37561 atgctgttcg ggcgacgccc cagcatcctg atccccagct taatcacagg gagatcaccg
    37621 cggttaacga taattctggc attcggattt ctgaccgtcg cccgtttcag tctggaccgt
    37681 tccttaacca gtttccggcg aacctttgtc tcccgggcaa cctgtgatga agactgatta
    37741 atcgccgttg tggccacgcg gttaatggcc attgctgaag ccgccggaat ggcgttttta
    37801 cgaacccggc tcagattgtc aatcgcctga tcaagccctt ttatcgccat aatttcaccc
    37861 tgcgtttatc gtcgccggtt aactgcgggt ggttgaccac ggttgagcca gagataacag
    37921 ctgcccccgt catccggaga aacacgatcc acccagaata tctcaccatt aatggtcagc
    37981 gtgtcaccac gccgcacggc acgaaccgta tccgtccgca caaataatga cgggctgctt
    38041 ccttcaatac ggaccccgcc accggcaaac cccagcgact ccggatcatc aaaaaccccc
    38101 tgaacttcgc tgccacactg tgcccccgag gtgaactgcg cacagagccc catcacttca
    38161 acgatcgtac tgtctacccc ggcgagggca gcatcaaagg cattctgaaa atcacgcata
    38221 ttcagccgtt ccgtgctgta tcatggccgt tgccagtgat gatggcacca gaacacgcat
    38281 accccgtaac gccagctcaa cgggacgacc tgtctccggg caatacccca ttacttgcag
    38341 gcacttccgt acccggacgg ctttaacatc atccggagca tccgtgttgt tcaactgctc
    38401 accatcgtct gtgtgatttt gatcagcccc gctctcatca gagtgcataa tgccctccgg
    38461 ggaaacagca agctcctctt cccactcaga cacacgttga gcaatatccg cagcactccc
    38521 cgacatatcc gcctcgcgcc ccagcaggcc agccagttga cgaagacgat tcagattttc
    38581 ttcttttgtt gccatctcag cctcctgtga aaaaagacac gggggcattt cgcccccgct
    38641 cacggattat ttcacctgta ccaccacaaa ctcatccgga tccggcagca ccatcagcgg
    38701 agcggactgc gtcatggtga attcacagga cggatcgccc acggtcagcc agtgtttcgg
    38761 gtaacgggaa gaagccacca ctccttcaga caacgcctgt gcatccttaa tggcaccata
    38821 gcaacgaatc ccctctgccg ccgtattccc cagcaccagc atgccctccg gcagataacg
    38881 tttttcggta ccgtcctctg ccacataaga cgttttcgcc accacaatgg ccagatcgcc
    38941 gtaatacccc ttgaaggaca ccactgcgcc cagatctttc actgccgttt cgagttgtga
    39001 atttgagccg cgacgggtat ccagtttttc gcggaacagc ttaaagccat tcagcagacg
    39061 ccagaccgta ccgtccataa tggcgatatt cacaaggccg ctggcctgat cgcagtagag
    39121 gtcaatatca tgcgtcggat caaacgtatc acggtcctgc tcagaccatt ttttaccgtc
    39181 agcctgctca atgttatttc cttcagagcg cccgaaatcc acctcgacag tatcaaactg
    39241 atccccttcc atggtgtatt tgccatacag cacggcattc accgcctgca tttcttccac
    39301 ctggacaatg gcgtgctctt cctgtttgag gttatcggta atgatacgca gacgacggta
    39361 ggccgggtcg ttcagctgag ccggatcttc accaggaagg cgctcaaccg cctgctggta
    39421 attaaattcg tgtttgggct tgacgtagcc cggacgtaac acgcgggttt caccaccgcg
    39481 atggcgaagc acttttcctt caacgatcgg ggagacatag gccgccaccg gcgtttttcc
    39541 ggtaattttg tccagcatca cctcttcggt gtggaaattc accgtacggc ggaaaaacag
    39601 ctccagaaac agcgcacgaa atttcacttt ttgttcggta taaccgagta actggcgggt
    39661 cgtaaacaat cccataaatc agttcctttc attcagaaat cagtcaggcc gccatggtgg
    39721 cctgataacg tgttacggca gagccgtgtg actcagggct gtgccggcaa aggcatttgc
    39781 ctttttgtgt tcatccacac tgtcaggcca gcggattgcc tccgtcgcaa aggtccccga
    39841 cttgtaatag gtcagcaccg tctctgtgcc ttcaagcggc agtaccagta tgccaaccgc
    39901 actaccggct ttctgtccat cccagaccac cagtttcccg gtggcttcat ccagcatcag
    39961 gggcgtcaga gccggtgttg cagaagaaat cccgctgctg cctgtggcgg tatgagccgg
    40021 atcattaccg gcaaaaatac gtacttccgc acgctgttca gtgatggttt tcgtcaccat
    40081 tttgttaaaa cctcatattg atggtcagca ctgacttcat ggcatggcca tgagcatttt
    40141 cacgtccgca tcaccgtctg ctgacgtctg tgacacgcca ccccgcaccg ctgccggtga
    40201 atgattcgcc atgaaatgtt caaacagggc ggttgtggat gcagagaccg gttcggcctt
    40261 acctgatccc gcagccagca cagcccgggc gttctccacg gtcattcccg ggcaggccgc
    40321 cagtttttca gcctgcgctt ctgccccttt tgcctcatcc agggccatga tctgatcacg
    40381 aagtgagggc ccggcatccg ccagtggtgc agccgccagg atcgggcggg ctttttccac
    40441 cgtcatctcc ggcatcgccg ccagcgttgc cgccagttgt tcacgaccgt tcgcttcttc
    40501 acacgccata atgcgatcgg cttcactctg cgcggatgcc accggctgct gcggtgccgc
    40561 cgcggccaga atcgcccggg cctgttcaac gctcatgccc tgttgccctg ccagcatcgt
    40621 ggcaagctgt tcacgtcctt tcgcttcctg gcatgtcagg atccccatca ctcgctggtt
    40681 ctcctgcacg gcggcttccg ttgcagttaa ttgcggcata gtgcctcctc tgacattact
    40741 gttcagcgcc gtggccatca cactgatggc atccgacgca ttgattaatt catccgccag
    40801 cccggcctca atgccggact gaccttcaaa aacagcggcc tctgttcccg tgactgcatc
    40861 aacagacaga ccggtaaaca tcgccacttt ttcggcaaac atccggcgcg ccgcatcaat
    40921 ccgctgctgc atgtcctggc gaacctctgc cggcaacgct tcaaactgat tgccatccac
    40981 cttgtgcgcc cctgagtaaa tcagcgtgat atccacaccg gcctgcgcca gatgaccggc
    41041 atagctgaca tggctcatca tcacgccaat ggaaccgata cgggatgtct gggtaaccag
    41101 ccgtcgggag caggccgacg ccagcagcat ggccgcagaa caggccgtgt cattacacag
    41161 tgcccaaacc ggcttctgct gccggaggcg gtaaatcatg tcagcgcagt caaacgcgcc
    41221 ggcggcctgc ccgcccggac tgtcaatgtc cagcagtatg ccccgcacct ggctatctgc
    41281 cattgcctgc tgaagacagg cgacaatgcc gtcatagcca gtcattccgg aaaatggccg
    41341 catccccccc agccggtgca ccagcgtgcc ggtcaccggc agtaccgcaa taccgttcac
    41401 cacccggtaa acacgggccg gtcgtttacc tccggccatg tactcgtccg tttcagccag
    41461 catcccggga gcatcaagct gtacctgctg ttgcggtacc gaaagacttg ctgcccccat
    41521 ctcgcgcccc agcgcgcaaa agaaaacccg cgcataggcg ggctccagaa gcagcggttc
    41581 attgaatgct gctgcaataa tgtgtgaaag attacgtctc acgtggtgtt gtctcctctt
    41641 ccggcctgcg actctccgct atctgctgct gatacgcctg cgctatccac accggacgtg
    41701 agagtccggc tttttcccgc tctgcagatt ccctgacctg ctggcggaaa atgtcctgat
    41761 aatcctcgcc catcagcgcc agctctttct catacgtgct cagtccggcc tcaatgcgca
    41821 tcactgattc ctgaacctcc ttgagcccgt caatggccat tcttccggct ccaatccact
    41881 cagcccgtga ccaggctgat cgcgcctgat aaaaatcaaa ccgtgcccgt ggcggacgaa
    41941 taatcccccg aagaagtgcc tcttccagcc agcaggaaaa catctgcgtg gccagccggg
    42001 acgcaataaa ttttcgccgc cccataaaat agcgccacga ctcattggcg gatgcgcggg
    42061 cacttgagta actgaccttc gagtaatcac gggacaactg ttcgtaggaa acgccaagac
    42121 cggcggcgat ataccgcagc agcgcctgtt caagcgccga aaatccattg tctgaatcct
    42181 gcgcggtctg aagtttcaga tcatcaccgg ggaaaaggtg cggaattttg acaccgccca
    42241 gcgtcacgct attcgtgtca taccaggtgg agaacttatc cagaatatta ataagcggat
    42301 tatccttctg cccctgcggc gcaccggcga tatattcaaa ggccttttcg gtatcaaggt
    42361 cactttcaat cgtcgctgca tacatcgcct tcactatggc cgactgaagc tgtgttgcct
    42421 gcagggaatc cagcatcttc agccgttcca taacgctgta aaactgattg gctccacggg
    42481 tctgcccgtc ctccaccggc tcgaaaatat gcagcatggc cggacgcccg gtgggtagtt
    42541 cacgcgggat ccgttcccat cgtccactcc cggagcgagg aaaatcatcc tcacagatat
    42601 ggtacgcaac ggcacggcca tatcgatcaa cctccacacc ggcccgcaga aaacggttcc
    42661 cgataccgtg tcctggcgtg tccacccgtt tcggactcac ggctttaaaa cgcgtacgaa
    42721 acagttgcgt actctccgta tcccagaccg gctgcacaaa gatttcgccg ttaaacgcat
    42781 gaacgcccac accttcacgg ataaattccg taaacgtgcg tttcccttcc acgtcgatct
    42841 caccaaacat cccttctgcg tattctgacc aggccgcctc cacctcatcg acaaaacttt
    42901 ttgccgcggt ctcccgcatc cccagccagc gccagttcgg acggtagcta atcagaaaca
    42961 tatgcccgac aatgtgatcc ttatgcaggg ccaccgcatt ggccgctatt ccgttattgc
    43021 gcaccagatc atctgcacgg gcattcccca gacgcaacgc gggcagcagg gccgcatcgg
    43081 cactctgcga gggtggcaac cactctgcca tttgcccgcc aaatcctgca ccgccaccgg
    43141 tgtagctgag gctctcccga agcggaacgc cgttcacatc aatcaggaca ggcgttcgtt
    43201 tcataacctc actcccagcg gacgacggcg acggcgggtt gtccccagta ccgactccgc
    43261 atcattgatc gcccggttaa gctcatccag agaagctgcc gtatattcaa ttctgcgacc
    43321 atctttctgg acagacacca cccgtttacc ggttaataaa tcaaggcgcg cctgacgcag
    43381 cgcctgcagt tcagcgactg taaccattca ctcctccgga cagcttcgct gccagttctt
    43441 taagggttgg ccgggtcgtc tcttcttccc gggattttgc cagtacagcc agatcaagct
    43501 gccagcgttg cacggacaca cgtaatgccg cgtaggcata caccaggcag tccagcgctt
    43561 cgttacgccg ctttttgtta tcccacagca gacgcatctt tcctttttcc cacttctcca
    43621 caagctcttc cgccaccagt tgctgcgcct ctgtctgcga aaaaatctcc ggatcatcag
    43681 gaaaacggat ggcatacgac gtggcttcat ccgcaggcgt gggatcggct ttcatacggg
    43741 catagagaat ttcttttgcg gtgtccgtcc ccacttcgca cagatacacg ccccgctgat
    43801 tgcgggtttt tggcatggtg atcaccggct tgccataaac agatgcacct tttaccggca
    43861 gcacccggaa aacaccgtgt ttttttgacc tctgatagac aatttcgcca tcgatccccc
    43921 cggtgtccca gcagacacgg gaaatggtca tttcggttcc gtctgcatgg cggtattttt
    43981 tgttgatcgc cacatccaca cgtaacagcg tctcttcctc atcgggacgc cccataatga
    44041 tgattttatc caccagaaag gcttcctctc ccggagccca tccccagaca tacatctcaa
    44101 aacggtttcg ctgcgagtca atgcccgccg tcagataaac cacccgggaa ggcaccgcag
    44161 ccgtgtaacg cacaacctta tccatcagca cctggtgatc gagtttttcg cccacggcct
    44221 cttcccaggt ctcgcccagc gtggtgttca caaaggtttt caggccgttg ggatctttca
    44281 gtgcatccag ccagtcatag acaatctgta cccaggtggt gaacggactg tacgccgtcc
    44341 agatatggaa tgtgatggag cgcggcggcg gaatttcatt atccgcggcg ctgaaaaatg
    44401 tcagaccgtc acgagtccac atgcccgtgt tttcacagat ccaccgcccg ttactctggt
    44461 caagctcaga ctgatggatc acacagccat gatgctcaca aaggtagaaa acactttctg
    44521 gcttattctt ctcccactta agaccgaaag gcgaggcatc atcgccaaat ttcagatact
    44581 gctcctcccc acagtgcgga cagggcacat aaaaacgcat gaaatgtgcc gactcgttag
    44641 cggctttttc gatctggcag gagcctttga ttttaggcgt cgagccgcga atggattttg
    44701 gccatacaga gccctcaata cgtttatccc ccagcagggt tggcgaaccc tctttttcaa
    44761 catccggttc gaacgaggaa agctcgtcat aacaaaccac atccacggat ttttcacggt
    44821 agttttttgc tgccgctccc cccagacacc agaaacccac accggaggaa aaacgcttca
    44881 gggtgagcgt attatcgcgg tgttttcttc cgaaccatgg agccagctcc agcaatgcag
    44941 gaacatccct tatcgttggc tcaacatgag atttcataaa atcttcagca gctgagtccg
    45001 tgggctgaaa aagaaggctg ttgcgtgatt tatgctcaat aaaataagcc tccactccca
    45061 gcaacatctt tgtataacca acacgggcag atttaatcag gttaacagtg cgaatcaaat
    45121 cgttgcccat acagttcatg atgccaacct gaaacggcag tgtttcccac cgccccgggg
    45181 tataagacga ctctttagga aggtaataat gtttattggc ccactgaact gtcgtcagtg
    45241 gaacaggaat aatgagagat aaaagccctg tagctatcgc accggctgca ttagctgcct
    45301 tctgtgcgtc tgaaatcatc gatccacccg cccacgtttt caccggcctt agctgcaaca
    45361 ttggaggctt tcgcgatttc agttttcacc acatcaaggt gtgatggtga aatgtccgga
    45421 tatttacgct gtaatgtcaa cggcacacgc acaagtatcc ccgaaatctc ctgtgccaca
    45481 cgttgcagaa tgaaggtaaa cagttcagtt tccagcacca ctccgtcttc acgggcattt
    45541 ttcagttcct gcgcatctgc ctgcgctttt gtgagccggt agcgttcata gtcaatggtg
    45601 ccgggttgta aatctgactc cgctgccgca cgcaaatcgg ccagttcttt gcggagcttt
    45661 tcgttttcga tatcagtttc cctctgcgca taccactgaa ttgccatggc agtatcaaat
    45721 acagattcaa tgcccttact gcctttggag acgcaaggga gcccctgaga ctgccagcgt
    45781 tcaatcgtcc gcgggtccac gttaaaaatt tcggcaagcc tctttttatt aaccttcata
    45841 gaacaaccca ttatcaaata caaggcccga catgaaaacg ccagaaaaag gcattttcgg
    45901 acactttcat gtcggacatt tatgaatgca atattaaaaa aaacaaaaag ttatattcga
    45961 gaagtaccga cacgattttc cctgaaaaat tttcataaat agtgaaaaac cgcgaggtcg
    46021 ccgccccgta acgatctgga tcaccggaaa ggacccgcca acgactttcg cgtgcaggca
    46081 ttaaaaattt tgcagttcca
//
LOCUS       DAPOAV010000031        43855 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.031, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000031 DAPOAV010000000
VERSION     DAPOAV010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 43855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43855
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.031"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(193..269)
                     /locus_tag="RN951_001967"
     tRNA            complement(193..269)
                     /locus_tag="RN951_001967"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(233..235),aa:Met,seq:cat)
     gene            478..1575
                     /gene="mltA"
                     /locus_tag="RN951_001968"
     CDS             478..1575
                     /gene="mltA"
                     /locus_tag="RN951_001968"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase A"
                     /protein_id="HDX2526969.1"
                     /translation="MKGRWVKYLLMGTVVAMLAACSSKPTDRGQQYKDGKFTQPFSLV
                     NQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGI
                     DAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLPSRAEIYAGA
                     LSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVLIDR
                     GEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRA
                     SVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFDIYQGIG
                     PEAGHRAGWYNHYGRVWVLKTAPGAGNVFSG"
     gene            1652..2458
                     /gene="tcdA"
                     /locus_tag="RN951_001969"
     CDS             1652..2458
                     /gene="tcdA"
                     /locus_tag="RN951_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA cyclic N6-threonylcarbamoyladenosine(37)
                     synthase TcdA"
                     /protein_id="HDX2526970.1"
                     /translation="MSVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSW
                     AAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRV
                     TVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQID
                     PTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGT
                     VCAMKATAEGPKRMDCASGFGAATMVTATFGFVAVSHALKKMMAKAARQG"
     gene            complement(2509..2952)
                     /gene="csdE"
                     /locus_tag="RN951_001970"
     CDS             complement(2509..2952)
                     /gene="csdE"
                     /locus_tag="RN951_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase sulfur acceptor subunit
                     CsdE"
                     /protein_id="HDX2526971.1"
                     /translation="MTNPQFAGHPFGTTVTAETLRNTFAPLSQWEDKYRQLIMLGKQL
                     PALPDELKAQAKEIAGCENRVWLGYTVTENGKMHFFGDSEGRIVRGLLAVLLTAVEGK
                     TAAELQAQSPLALFDELGLRAQLSASRSQGLNALSEAIIAAAKQV"
     gene            complement(2952..4157)
                     /gene="csdA"
                     /locus_tag="RN951_001971"
     CDS             complement(2952..4157)
                     /gene="csdA"
                     /locus_tag="RN951_001971"
                     /EC_number="3.13.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase CsdA"
                     /protein_id="HDX2526972.1"
                     /translation="MNVFNPAQFRAQFPALQDAGVYLDSAATALKPEAVVEATRQFYS
                     LSAGNVHRSQFAEAQRLTARYEAAREKVAQLLNAPDDKTIVWTRGTTESINMVAQCYA
                     RPRLQPGDEIIVSVAEHHANLVPWLMVAQQTGAKVVKLPLNAQRLPDVDLLPELITPR
                     SRILALGQMSNVTGGCPDLARAITFAHSAGMVVMVDGAQGAVHFPADVQQLDIDFYAF
                     SGHKLYGPTGIGVLYGKSELLEAMSPWLGGGKMIHEVSFDGFTTQSAPWKLEAGTPNV
                     AGVIGLSAALEWLADYDINQAESWSRSLATLAEEALAKRPGFRSFRCQDSSLLAFDFA
                     GVHHSDMVTLLAEYGIALRAGQHCAQPLLAELGVTGTLRASFAPYNTKSDVDALVNAV
                     DRALELLVD"
     gene            4349..4576
                     /locus_tag="RN951_001972"
     CDS             4349..4576
                     /locus_tag="RN951_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417289.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgdI/YgdR family lipoprotein"
                     /protein_id="HDX2526973.1"
                     /translation="MKKTAAIISACMLTFALSACSGSNYVMHTNDGRTIVSDGKPQTD
                     NDTGMISYKDANGNKQQINRTDVKEMVELDQ"
     gene            4927..5844
                     /gene="gcvA"
                     /locus_tag="RN951_001973"
     CDS             4927..5844
                     /gene="gcvA"
                     /locus_tag="RN951_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system transcriptional
                     regulator GcvA"
                     /protein_id="HDX2526974.1"
                     /translation="MSKRLPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSL
                     EDFLGLKLFRRRNRSLLLTEEGQSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLP
                     SFAIHWLVPRLSSFNSAYPGIDVRIQAVDRQEDKLADDVDVAIFYGRGNWPGLRVEKL
                     YAEYLLPVCSPLLLTGEKPLKTPEDLAKHTLLHDASRRDWQTYTRQLGLNHINVQQGP
                     IFSHSAMVLQAAIHGQGVALANNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQA
                     ELGKIAAFRQWILAKAAAEQEKFRFRYEQ"
     gene            5863..6258
                     /locus_tag="RN951_001974"
     CDS             5863..6258
                     /locus_tag="RN951_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF423 domain-containing protein"
                     /protein_id="HDX2526975.1"
                     /translation="MTSRFMLIFAAISGFIFVALGAFGAHVLSKTMGAVEMGWIQTGL
                     EYQAFHTLAILGLAVAMQRRISIWFYWSSVFLALGTVLFSGSLYCLALSHLRLWAFVT
                     PVGGVSFLAGWALMLVGAIRLKRKGVSHE"
     gene            6251..7351
                     /gene="rlmM"
                     /locus_tag="RN951_001975"
     CDS             6251..7351
                     /gene="rlmM"
                     /locus_tag="RN951_001975"
                     /EC_number="2.1.1.186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010435097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytidine(2498)-2'-O)-methyltransferase
                     RlmM"
                     /protein_id="HDX2526976.1"
                     /translation="MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIY
                     ECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGE
                     LRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYT
                     GYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDL
                     GACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVC
                     DMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINA
                     QIQARQLYHDREEVTVHVRRIWAAVGGRRDER"
     gene            complement(7395..8126)
                     /gene="fucR"
                     /locus_tag="RN951_001976"
     CDS             complement(7395..8126)
                     /gene="fucR"
                     /locus_tag="RN951_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose operon activator"
                     /protein_id="HDX2526977.1"
                     /translation="MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQT
                     QGKILRNHGRAKYIHRQNQDSGDPFHIRLKSHYAHKADIAREALAWIEEGMVIALDAS
                     STCWYLARQLPDINIQVFTNSHPICHELGKRERIQLISSGGTLERKYGCYVNPSLISQ
                     LKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEA
                     RIGHLDEVTHIISDERQVATSLVTA"
     gene            complement(8184..8606)
                     /gene="fucU"
                     /locus_tag="RN951_001977"
     CDS             complement(8184..8606)
                     /gene="fucU"
                     /locus_tag="RN951_001977"
                     /EC_number="5.1.3.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose mutarotase"
                     /protein_id="HDX2526978.1"
                     /translation="MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIR
                     ADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDI
                     IRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP"
     gene            complement(8608..10026)
                     /gene="fucK"
                     /locus_tag="RN951_001978"
     CDS             complement(8608..10026)
                     /gene="fucK"
                     /locus_tag="RN951_001978"
                     /EC_number="2.7.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417283.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculokinase"
                     /protein_id="HDX2526979.1"
                     /translation="MKQEVILVLDCGATNVRAIAVNRQGKIVARASTPNASDIAMENN
                     TWHQWSLDAILQRFADCCRQINSELTECHIRGIAVTTFGVDGALVDKQGNLLYPIISW
                     KCPRTAAVMDNIEQLISAQRLQAISGVGAFSFNTLYKLVWLKENHPQLLERAHAWLFI
                     SSLINHRLTGEFTTDITMAGTSQMLDIQQRDFSPQILQATGIPRRLFPRLVEAGEQIG
                     TLQNSAAAMLGLPVGIPVISAGHDTQFALFGAGADQNEPVLSSGTWEILMVRSAQVDT
                     SLLSQYAGSTCELDSQAGLYNPGMQWLASGVLEWVRKLFWTAETPWQMLIEEARLIAP
                     GADGVKMQCDLLSCQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLQMLEKIGHFKA
                     SELLLVGGGSRNTLWNQIKANMLDIPVKVLDDAETTVAGAALFGWYGVGEFNSPEEAR
                     AQIHYQYRYFYPQTEPEFIEEV"
     gene            complement(10135..11910)
                     /gene="fucI"
                     /locus_tag="RN951_001979"
     CDS             complement(10135..11910)
                     /gene="fucI"
                     /locus_tag="RN951_001979"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HDX2526980.1"
                     /translation="MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALLTEK
                     LRHACGAAVECVISDTCIAGMAEAAACEEKFSSQNVGLTITVTPCWCYGSETIDMDPT
                     RPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLL
                     RFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRID
                     QKIYDEAELEMALAWADKNFRYGEDENNKQYQRNAEQSRAVLRESLLMAMCIRDMMQG
                     NSKLADIGRVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEAILNSSFDWNGVREPFVV
                     ATENDSLNGVAMLMGHQLTGTAQVFADVRTYWSPEAIERVTGHKLDGLAEHGIIHLIN
                     SGSAALDGSCKQRDSEGNPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRF
                     LTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKDVHDILNKRTNSTWPTTWFAPRL
                     TGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLASMLRIPVCMHNVEETKVYRPSA
                     WAAHGMDIEGQDYRACQNYGPLYKR"
     gene            complement(11943..13259)
                     /gene="fucP"
                     /locus_tag="RN951_001980"
     CDS             complement(11943..13259)
                     /gene="fucP"
                     /locus_tag="RN951_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose:H+ symporter permease"
                     /protein_id="HDX2526981.1"
                     /translation="MGNTSIQTQSYRAVDKDAGQSRSYIIPFALLCSLFFLWAVANNL
                     NDILLPQFQQAFTLTNFQAGLIQSAFYFGYFIIPIPAGILMKKLSYKAGIITGLFLYA
                     LGAALFWPAAEIMNYTLFLVGLFIIAAGLGCLETAANPFVTVLGPESSGHFRLNLAQT
                     FNSFGAIIAVVFGQSLILSNVPHQSQDVLDKMSPEQLSAYKHSLVLSVQTPYMIIVAI
                     VLLVALLIMLTKFPALQSDNHSDAKQGSFSASLSRLARIRHWRWAVLAQFCYVGAQTA
                     CWSYLIRYAVEEIPGMTAGFAANYLTGTMVCFFIGRFTGTWLISRFAPHKVLAAYALI
                     AMALCLISAFAGGHVGLIALTLCSAFMSIQYPTIFSLGIKNLGQDTKYGSSFIVMTII
                     GGGIVTPVMGFVSDAAGNIPTAELIPALCFAVIFIFARFRSQTATN"
     gene            13806..14453
                     /gene="fucA"
                     /locus_tag="RN951_001981"
     CDS             13806..14453
                     /gene="fucA"
                     /locus_tag="RN951_001981"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HDX2526982.1"
                     /translation="MERNKLARQIIDTCLEMTRLGLNQGTAGNVSVRYQDGMLITPTG
                     IPYEKLTESHIVFIDGNGKHEEGKLPSSEWRFHMAAYQSRPDANAVVHNHAVHCTAVS
                     ILNRPIPAIHYMIAAAGGNSIPCAPYATFGTRELSEHVALALKNRKATLLQHHGLIAC
                     EVNLEKALWLAHEVEVLAQLYLTTLAITDPVPVLSDEEIAVVLEKFKTYGLRIEE"
     gene            14481..15629
                     /gene="fucO"
                     /locus_tag="RN951_001982"
     CDS             14481..15629
                     /gene="fucO"
                     /locus_tag="RN951_001982"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417279.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HDX2526983.1"
                     /translation="MANRMILNETAWFGRGAVGALTDEVKRRGYQKALIVTDKTLVQC
                     GVVAKVTDKMDAAGLAWAIYDGVVPNPTITVVKEGLGVFQNSGADYLIAIGGGSPQDT
                     CKAIGIISNNPEFADVRSLEGLSPTNKPSVPILAIPTTAGTAAEVTINYVITDEEKRR
                     KFVCVDPHDIPQVAFIDADMMDGMPPALKAATGVDALTHAIEGYITRGAWALTDALHI
                     KAIEIIAGALRGSVAGDKDAGEEMALGQYVAGMGFSNVGLGLVHGMAHPLGAFYNTPH
                     GVANAILLPHVMRYNADFTGEKYRDIARVMGVKVEGMSLEEARNAAVEAVFALNRDVG
                     IPPHLRDVGVRKEDIPALAQAALDDVCTGGNPREATLEDIVELYHTAW"
     gene            complement(15684..16439)
                     /gene="xni"
                     /locus_tag="RN951_001983"
     CDS             complement(15684..16439)
                     /gene="xni"
                     /locus_tag="RN951_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417278.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flap endonuclease Xni"
                     /protein_id="HDX2526984.1"
                     /translation="MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTH
                     AVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNE
                     ADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGV
                     QPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKL
                     ETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR"
     gene            complement(16551..17918)
                     /gene="sdaB"
                     /locus_tag="RN951_001984"
     CDS             complement(16551..17918)
                     /gene="sdaB"
                     /locus_tag="RN951_001984"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase II"
                     /protein_id="HDX2526985.1"
                     /translation="MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARNLLKDVTR
                     VVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDIDSIPGFIQDVNTHGRLMLANGQ
                     HEVEFPVDQCMNFHADNLSLHENGMRITALAGDKVVYSQTYYSIGGGFIVDEEHFGQQ
                     NSAPVEVPYPYSSAADLQKHCQETGLSLSGLMMKNELALHSKEELEQHLANVWEVMRG
                     GIERGISTEGVLPGKLRVPRRAAALRRMLVSQDKTTTDPMAVVDWINMFALAVNEENA
                     AGGRVVTAPTNGACGIIPAVLAYYDKFIREVNANSLARYLLVASAIGSLYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGASPAQVCIAAEIAMEHNLGLTCDPVAGQVQVPC
                     IERNAIAAVKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMK
                     IVACD"
     gene            complement(17976..19265)
                     /gene="sdaC"
                     /locus_tag="RN951_001985"
     CDS             complement(17976..19265)
                     /gene="sdaC"
                     /locus_tag="RN951_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease SdaC"
                     /protein_id="HDX2526986.1"
                     /translation="METTQTSTIASKDSRSAWRKTDTMWMLGLYGTAIGAGVLFLPIN
                     AGVGGMIPLIIMAILAFPMTFFAHRGLTRFVLSGKNPGEDITEVVEEHFGIGAGKLIT
                     LLYFFAIYPILLVYSVAITNTVESFMSHQLGMTPPPRAILSLILIVGMMTIVRFGEQM
                     IVKAMSILVFPFVGVLMLLALYLIPQWNGAALETLSLDTASATGNGLWMTLWLAIPVM
                     VFSFNHSPIISSFAVAKREEYGDMAEQKCSKILAFAHIMMVLTVMFFVFSCVLSLTPA
                     DLAAAKEQNISILSYLANHFNAPVIAWMAPIIAIIAITKSFLGHYLGAREGFNGMVIK
                     SLRGKGKSIEINKLNRITALFMLVTTWIVATLNPSILGMIETLGGPIIAMILFLMPMY
                     AIQKVPAMRKYSGHISNVFVVVMGLIAISAIFYSLFS"
     gene            complement(19822..21186)
                     /gene="ppnN"
                     /locus_tag="RN951_001986"
                     /gene_synonym="ygdH"
     CDS             complement(19822..21186)
                     /gene="ppnN"
                     /locus_tag="RN951_001986"
                     /gene_synonym="ygdH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide 5'-monophosphate nucleosidase"
                     /protein_id="HDX2526987.1"
                     /translation="MITHISPLGSMDMLSQLEVDMLKRTASSDLYQLFRNCSLAVLNS
                     GSLTDNSKELLSRFENFDINVLRRERGVKLELINPPEEAFVDGRIIRALQANLFAVLR
                     DILFVYGQIHNTVRFPNLNLDNSVHITNLVFSILRNARALHVGEAPNMVVCWGGHSIN
                     ENEYLYARRVGNQLGLRELNICTGCGPGAMEAPMKGAAVGYAQQRYKDSRFIGMTEPS
                     IIAAEPPNPLVNELIIMPDIEKRLEAFVRIAHGIIIFPGGVGTAEELLYLLGILMNPA
                     NKDQVLPLILTGPKESADYFRVLDEFVVHTLGENARRHYRIIIDDAAEVARQMKKSMP
                     LVKENRRDTGDAYSFNWSMRIAPDLQMPFEPSHENMANLKLCPDQPVEVLAADLRRAF
                     SGIVAGNVKEVGIRAIEEFGPYKINGDKEIMRRMDDLLQGFVAQHRMKLPGSAYIPCY
                     EICT"
     gene            complement(21298..22146)
                     /gene="queF"
                     /locus_tag="RN951_001987"
     CDS             complement(21298..22146)
                     /gene="queF"
                     /locus_tag="RN951_001987"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HDX2526988.1"
                     /translation="MSSYANHQALAGLTLGKSTDYRDTYDASLLQGVPRSLNRDPLGL
                     KADNLPFHGTDIWTLYELSWLNAKGLPQVAVGHVELDYTSVNLIESKSFKLYLNSFNQ
                     TRFNNWDEVRQTLERDLSTCAQGKVSVALYRLDELEGQPIGHFNGTCIDDQDITIDNY
                     EFTTDYLENATSGEKVEEETLVSHLLKSNCLITHQPDWGSIQIQYRGRQIDREKLLRY
                     LVSFRHHNEFHEQCVERIFNDLLRFCQPEKLSVYARYTRRGGLDINPWRSNSDFVPST
                     TRLVRQ"
     gene            22214..22759
                     /gene="syd"
                     /locus_tag="RN951_001988"
     CDS             22214..22759
                     /gene="syd"
                     /locus_tag="RN951_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SecY-interacting protein"
                     /protein_id="HDX2526989.1"
                     /translation="MDDLTAQALKDFTARYCDAWHEEHKSWPLSEELYGVPSPCIIST
                     TEDAVYWQPQPFTGEQNVNSVERAFDIVIQPTIHTFYTTQFAGDMHAQFGDIKLTLLQ
                     TWSEDDFRRVQENLIGHLVTQKRLKLPPTLFIATLEEELEVISVCNLSGEVCKETLGT
                     RKRTHLASNLAEFLNQLKPLL"
     gene            23381..23710
                     /locus_tag="RN951_001989"
     CDS             23381..23710
                     /locus_tag="RN951_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqcC family protein"
                     /protein_id="HDX2526990.1"
                     /translation="MTTHDRVRLQLQALEALLREHQHWRNDEPQPHQFNSTQPFFMDT
                     MEPLEWLQWVLIPRMHDLLDNKQPLPGAFAVAPYYEMALATDHPQRALILAELEKLDA
                     LFADDAS"
     gene            23710..24492
                     /gene="truC"
                     /locus_tag="RN951_001990"
     CDS             23710..24492
                     /gene="truC"
                     /locus_tag="RN951_001990"
                     /EC_number="5.4.99.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(65) synthase TruC"
                     /protein_id="HDX2526991.1"
                     /translation="MLEILYQDEWLVAVNKPSGWLVHRSWLDRDEKVVVMQTVRDQIG
                     QHVFTAHRLDRPTSGVLLMGLSSEAGRLLAQQFEQHQIQKRYHAIVRGWLMEEAVLDY
                     PLVEELDKIADKFAREDKGSQPAVTHYRGLATVEMPVATGRYPTTRYGLVELEPKTGR
                     KHQLRRHLAHLRHPIIGDSKHGDLRQNRSGAEHFGLQRLMLHASQLSLTHPFTGEPLT
                     IHAGLDDTWMQALSQFGWRGLLPENERVEFSAPSGQDGEISS"
     gene            24510..24959
                     /locus_tag="RN951_001991"
     CDS             24510..24959
                     /locus_tag="RN951_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDX2526992.1"
                     /translation="MAEIGIFVGTMYGNSLLVAEEAEAILTAQGHKATVFEDPELSDW
                     LPYQDKYVLVVTSTTGQGDLPDSIVPLFQGIKDSLGFQPNLRYGVIALGDSSYVNFCN
                     GGKQFDALLQEQSAQRVGEILLIDASENPEPETESNPWVEQWGTLLS"
     gene            25394..26746
                     /gene="gudP"
                     /locus_tag="RN951_001992"
     CDS             25394..26746
                     /gene="gudP"
                     /locus_tag="RN951_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate/glucarate/glycerate transporter
                     GudP"
                     /protein_id="HDX2526993.1"
                     /translation="MSSLSQAASSVEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGS
                     EMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFGSKRVYFWSIFIWSMFTLLQ
                     GFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQY
                     FATVIFAPIMGWLTHEVGWSHVFFFMGGLGIVISFIWLKVIHEPNQHPGVNQKELEYI
                     AAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFP
                     VYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTGSLNIARKTPIVMGM
                     LLSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPKEISGLSGGLFNMF
                     GNISGIVTPIAIGYIVGTTGSFNGALIYVGVHALIAVLSYLVLVGDIKRIELKPVAGQ
                     "
     gene            26748..28088
                     /locus_tag="RN951_001993"
     CDS             26748..28088
                     /locus_tag="RN951_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucarate dehydratase-related protein"
                     /protein_id="HDX2526994.1"
                     /translation="MATQSSPVITDMKVIPVAGHDSMLLNIGGAHNAYFTRNIVVLTD
                     NAGHTGIGEAPGGDVIYQTLVDAIPMVLGQEVARLNKVVQQVHKGNQAADFDTFGKGA
                     WTFELRVNAVAALEAALLDLLGKALNVPVCELLGPGKQREAITVLGYLFYIGDRTKTD
                     LPYVENTPGNHEWYQLRHQKAMNSEAVVRLAEASQDRYGFKDFKLKGGVLPGEQEIDT
                     VRALKKRFPDARITVDPNGAWLLDEAISLCKGLNDVLTYAEDPCGAEQGFSGREVMAE
                     FRRATGLPVATNMIATNWREMGHAVMLNAVDIPLADPHFWTLSGAVRVAQLCDDWGLT
                     WGCHSNNHFDISLAMFTHVGAAAPGNPTAIDTHWIWQEGDCRLTQNPLEIKNGKIAVP
                     DAPGLGVELDWEQVQKAHEAYKRLPGGARNDAGPMQYLIPGWTFDRKRPVFGRH"
     gene            28109..29449
                     /gene="gudD"
                     /locus_tag="RN951_001994"
     CDS             28109..29449
                     /gene="gudD"
                     /locus_tag="RN951_001994"
                     /EC_number="4.2.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucarate dehydratase"
                     /protein_id="HDX2526995.1"
                     /translation="MSSQFTTPVVTEMQVIPVAGHDSMLMNLSGAHAPFFTRNIVIIK
                     DNSGHTGVGEIPGGEKIRKTLEDAIPLVVGKTLGEYKNVLTLVRNTFADRDAGGRGLQ
                     TFDLRTTIHVVTGIEAAMLDLLGQHLGVNVASLLGDGQQRSEVEMLGYLFFVGDRKAT
                     PLPYQSQPDDSCDWYRLRHEEAMTPDAVVRLAEAAYEKYGFNDFKLKGGVLAGEEEAE
                     SIVALAQRFPQARITLDPNGAWSLNEAIKIGKYLKGSLAYAEDPCGAEQGFSGREVMA
                     EFRRATGLPTATNMIATDWRQMGHTLSLQSVDIPLADPHFWTMQGSVRVAQMCHEFGL
                     TWGSHSNNHFDISLAMFTHVAAAAPGKITAIDTHWIWQEGNQRLTKEPFEIKGGLVQV
                     PEKPGLGVEVDMDQVMKAHELYQKHGLGARDDAMGMQYLIPGWTFDNKRPCMVR"
     gene            complement(29681..32437)
                     /gene="barA"
                     /locus_tag="RN951_001995"
     CDS             complement(29681..32437)
                     /gene="barA"
                     /locus_tag="RN951_001995"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase BarA"
                     /protein_id="HDX2526996.1"
                     /translation="MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDA
                     GASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFH
                     LDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYI
                     ALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRR
                     GQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQN
                     VELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTI
                     ERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTL
                     NIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIR
                     DTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNR
                     GSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYS
                     PTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKL
                     KQDGIGACLLKPLTPTRLLPALTEFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKL
                     IGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQ
                     QTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPE
                     VNEIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGL
                     VDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELLELLDEMDNVAREAS
                     KILG"
     gene            32494..33795
                     /gene="rlmD"
                     /locus_tag="RN951_001996"
     CDS             32494..33795
                     /gene="rlmD"
                     /locus_tag="RN951_001996"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDX2526997.1"
                     /translation="MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKALFIPGL
                     LPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQR
                     SKSAALARLMKHEVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVK
                     QCPILAPQLEALLPKVRACLGSLQAMRHLGHVELVQATSGTLMILRHTAPLSSADREK
                     LERFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVA
                     RALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLQ
                     NVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPA
                     TLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK"
     gene            33843..36077
                     /locus_tag="RN951_001997"
     CDS             33843..36077
                     /locus_tag="RN951_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HDX2526998.1"
                     /translation="MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQ
                     QTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKS
                     VVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHL
                     REVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLL
                     HERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDV
                     RAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTV
                     EIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGE
                     MLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVP
                     FTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAG
                     RQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNK
                     PSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGF
                     ITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRD
                     ITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARR
                     LHGS"
     gene            36155..36403
                     /gene="mazE"
                     /locus_tag="RN951_001998"
     CDS             36155..36403
                     /gene="mazE"
                     /locus_tag="RN951_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin MazE"
                     /protein_id="HDX2526999.1"
                     /translation="MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLII
                     EPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW"
     gene            36403..36738
                     /gene="mazF"
                     /locus_tag="RN951_001999"
     CDS             36403..36738
                     /gene="mazF"
                     /locus_tag="RN951_001999"
                     /EC_number="3.1.27.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease MazF"
                     /protein_id="HDX2527000.1"
                     /translation="MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTG
                     MCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLI
                     KAKINVLIG"
     gene            36809..37600
                     /gene="mazG"
                     /locus_tag="RN951_002000"
     CDS             36809..37600
                     /gene="mazG"
                     /locus_tag="RN951_002000"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HDX2527001.1"
                     /translation="MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVL
                     DAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFAD
                     SSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWT
                     TLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQK
                     ANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL"
     gene            37828..39465
                     /gene="pyrG"
                     /locus_tag="RN951_002001"
     CDS             37828..39465
                     /gene="pyrG"
                     /locus_tag="RN951_002001"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase (glutamine hydrolyzing)"
                     /protein_id="HDX2527002.1"
                     /translation="MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPY
                     INVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRK
                     ERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQM
                     AVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPA
                     NERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEW
                     EQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVE
                     TRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARH
                     VANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVD
                     DSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPW
                     FVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK"
     gene            39553..40851
                     /gene="eno"
                     /locus_tag="RN951_002002"
     CDS             39553..40851
                     /gene="eno"
                     /locus_tag="RN951_002002"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HDX2527003.1"
                     /translation="MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTG
                     SREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTEN
                     KSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHA
                     DNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGS
                     NAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHF
                     LEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKG
                     IANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQI
                     KTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA"
     gene            complement(40907..41269)
                     /locus_tag="RN951_002003"
     CDS             complement(40907..41269)
                     /locus_tag="RN951_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527004.1"
                     /translation="MSKILANHPRLSKFVFGLFGAAGMIWLNKAFQGDELFQLITSLL
                     ALDTFVNFCIYSLINPIPEANDFLWDYKVHQRKYSSNISHNDFVSNVRNSRKIVRILI
                     LVGITFINVIALLTKLKM"
     gene            complement(41305..42210)
                     /locus_tag="RN951_002004"
     CDS             complement(41305..42210)
                     /locus_tag="RN951_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001479509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgcG family protein"
                     /protein_id="HDX2527005.1"
                     /translation="MKNLILLLVLICSSAFAVQVPVPEFAKYINDLTGTLTREEVSTL
                     TSQIKTLTQKSHAQLIVLVVETTGDETIEQYATRVFERWQPGHKNLDDGILLVVAWQD
                     HTVHIEIGYGLEGILTDAQSGQIIRNSIIPAFKKGDLAVGLQQGIGDIETRLSENDLV
                     NNTSPDHPLPFSGWWALLVWAIVLTFISARGYVKTLGVICFAAIILAFVLPIAGYSGS
                     WGVLATLLCFATPFLVVAIAFTPFGRKVRDSMRSANRPSRYERSNSASRHSSSSSSSS
                     SSSFNNDNFSGGGGSSGGGGASGRW"
     gene            complement(42224..42826)
                     /locus_tag="RN951_002005"
     CDS             complement(42224..42826)
                     /locus_tag="RN951_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000944219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HDX2527006.1"
                     /translation="MLRTFIVIIFIFNLSGCGYNDIQTYDEQVNASWSEVLNQYQRRA
                     DLIPNLVASIKGYSNHEKDVLEAVTLARSQANRASSDLQQTPGNEQKLQAWQQAQAQV
                     IRTLGQLTIISERYPELKAQELYQNLMVQLEGSENRIAVARGRYIKAIEQYNVTIRKF
                     PAVLTAKVMDYTPKKNYLPDDVAAVSKAPTIDFSQNASAH"
     gene            42999..43670
                     /gene="queE"
                     /locus_tag="RN951_002006"
     CDS             42999..43670
                     /gene="queE"
                     /locus_tag="RN951_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="HDX2527007.1"
                     /translation="MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTW
                     EKLEDREVSLFSILAKTKESDKWGSASSEDLLAVIGRQGYTARHVVITGGEPCIHDLL
                     PLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYDVLSQALERANEIKH
                     PVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHK
                     YLNIA"
BASE COUNT        10945 a        10551 c        11533 g        10826 t
ORIGIN      
        1 tttatagaat atgtaagtga agttcattgg tggggtatat atttaatata taaataagat
       61 ggatggcttt gattgggggg ggatcaacgg tttactcatt gtttcaggct tcactgaaac
      121 ggataaggaa gcgtaaaaac gaaaaaaccg caagctaaag gtagcgttgc ggtttctgat
      181 attctaataa attggttgcg ggggccggat ttgaaccgac gaccttcggg ttatgagccc
      241 gacgagctac caggctgctc caccccgcgt ccgtggatgc gcactatact ccgctcgcgt
      301 tttcatgcaa cctttttttt accccgatca cggatttagc atgattttga acaaaaacaa
      361 accactaaag cctatttttt gtgcaaaatt tgcgtcaggg agaggctgct catttcatta
      421 aacgcggcgg tttgttatct tcgttgcgcc ttatttttta acctgaagaa gagaacaatg
      481 aaaggacgtt gggtaaagta ccttcttatg ggcacggttg tggcaatgct tgccgcctgc
      541 tcttccaaac caaccgatcg cggacagcaa tataaagacg ggaaatttac ccagcctttc
      601 tctctggtga accagccaga tgccgttggc gcgccgatta acgccggtga ttttgccgag
      661 caaattaacc atatccgtaa ttcgtcaccg cgtctgtatg gcaaccagag taatgtttat
      721 aacgcggtgc aagagtggct gcgcgcaggc ggtgataccc gcaatatgcg ccagttcggc
      781 attgatgcct ggcagatgga aggtgccgac aactatggta acgtgcagtt tacaggctat
      841 tacacgccgg taattcaggc gcgccatacc cgccagggcg agttccagta tcctatttac
      901 cgtatgccgc caaaacgtgg tcgtctgccg tctcgtgcgg agatctacgc aggggcgctg
      961 agtgataaat atattctcgc ttacagcaac tccctgatgg ataacttcat tatggatgtg
     1021 cagggtagcg ggtatatcga ctttggtgat ggcagtccgc ttaacttttt cagctatgca
     1081 gggaaaaacg gtcatgccta tcgcagcatt ggtaaggtgc tgatcgaccg tggcgaagtg
     1141 aaaaaagaag atatgtcgat gcaggcgatt cgtcattggg gcgaaacaca cagtgaagcc
     1201 gaggttcgcg agctgctgga acagaacccg tctttcgttt tctttaaacc gcaatctttt
     1261 gcaccggtga aaggggcaag tgcggtgccg ctggttggcc gtgcttctgt tgcctccgat
     1321 cgttcaatta ttccgccagg tacaaccttg ctggcagaag tgccgctgct ggataataac
     1381 ggcaaattta acggtcagta cgaattgcgt ctgatggtgg cgctggatgt cggtggcgca
     1441 atcaaaggcc aacacttcga tatctatcaa gggatcgggc cggaagccgg acaccgcgca
     1501 ggttggtaca accactatgg acgtgtctgg gtgctgaaaa ccgccccggg cgcaggtaac
     1561 gtctttagtg gctgatgtgt tattctgtat accgttttta cggatacgac agggtgaggg
     1621 ataacctcac cctttttaat tctgaggtgc tatgtctgtg gtaattagtg atgcatggcg
     1681 tcagcgtttt ggtggcacag cgcgtctgta tggtgaaaaa gcgttgcaac tgtttgctga
     1741 cgcgcatatt tgtgtggttg gtatcggtgg tgtcggttcc tgggcagcgg aagcgctggc
     1801 gcgcacgggg attggcgcaa tcacgcttat cgatatggat gatgtgtgcg tcaccaatac
     1861 caatcggcaa attcacgctc tgcgcgataa cgtcgggctg gcaaaagcgg aagtcatggc
     1921 ggagcgtatt cgccagatta acccggagtg ccgtgtaacg gtggtggatg atttcgtgac
     1981 gccggataac gtagcgcagt atatgagcgt gggttattcg tacgtgattg atgccattga
     2041 tagtgtacgg cccaaagcgg cgctgattgc ttattgtcgg cgcaataaaa tcccgctggt
     2101 cacgaccggt ggcgcgggtg ggcagattga cccgacgcag attcaggtta ccgatctggc
     2161 gaaaacgatt caggatccgc tggcggcgaa gttgcgcgag cgcctgaaaa gcgattttgg
     2221 cgtagtgaaa aacagtaaag gtaagctcgg cgtcgattgc gtgttttcta ctgaagcgct
     2281 ggtgtacccg cagtcagacg gtactgtgtg tgcgatgaaa gccacggcag aagggccgaa
     2341 gcggatggat tgtgcatctg gatttggcgc ggcaacgatg gtgaccgcca cctttgggtt
     2401 tgttgcggtt tctcatgcgc tgaagaagat gatggcgaaa gcggcgcgtc agggttaaac
     2461 aatcaggtcg gatgcgacgc gaacgtctta tccgacctgg ttctgtgctt aaacctgctt
     2521 cgccgcagcg ataatcgcct cgcttaacgc attcaacccc tggctgcgtg aggcgctaag
     2581 ctgtgcacgc aatcccagct catcaaacaa tgccagcggc gactgtgcct gcaattcggc
     2641 ggcggttttc ccctcaacgg cagtcaacaa caccgccaac aggccgcgca caatgcgccc
     2701 ttcgctatcg ccaaagaagt gcattttacc gttttcagtc acggtatatc ccagccagac
     2761 gcggttttcg catccggcaa tctctttagc ctgcgctttt aactcgtctg gcaaagccgg
     2821 aagctgtttc cccagcatga tcaactggcg atatttatct tcccattgcg acaacggagc
     2881 gaaggtattg cgtaacgttt ctgcggttac ggttgtgccg aacggatgtc cggcgaattg
     2941 cgggtttgtc attaatccac caataattcc agcgcgcggt caacggcatt caccagcgca
     3001 tccacatcac tctttgtatt atatggcgca aatgaggcgc gcagtgtgcc ggttacgcct
     3061 aattctgcca gtagcggctg agcgcaatgt tgcccggccc gcaaggcaat accgtactcc
     3121 gccagtagcg tcaccatatc gctgtgatga acgccagcaa aatcaaaggc cagcaggctg
     3181 gaatcctggc agcggaatga acgaaagcct ggacgtttcg ccagcgcttc ttctgcaagc
     3241 gttgctaagc tacggctcca gctttcggcc tggttgatat cgtaatctgc cagccattcc
     3301 agcgccgcgc ttaatcctat gacgccagcg acatttggcg ttcctgcttc cagtttccac
     3361 ggcgcagatt gagtggtgaa accgtcaaaa ctcacttcgt gaatcatttt gccgccaccc
     3421 agccagggcg acatcgcttc cagcagttct gatttaccat acagcacgcc gatacctgtc
     3481 gggccataca gtttgtgacc tgaaaaagca tagaaatcga tatctagttg ctgaacatct
     3541 gcggggaaat gcaccgcccc ctgagcacca tcaaccatca ccaccatccc ggctgaatga
     3601 gcaaaggtaa tcgctcgcgc cagatccggg caaccgccag taacgttcga catctgaccc
     3661 aacgccagaa tccgactacg gggagtaatc agttctggca acaaatcgac atccggcagt
     3721 cgctgcgcat taagcggcaa tttcaccact ttggctccag tttgttgggc gaccatcagc
     3781 caggggacga ggttagcgtg gtgttctgcc acgctgacaa taatctcatc gcccggttgc
     3841 agacgcggac gcgcatagca ttgtgccacc atgttgatgg attcagtggt gccgcgcgtc
     3901 cagacgatag ttttatcatc cggtgcattc agtaattgcg ccactttttc ccgcgcagct
     3961 tcataacgcg cggtcaggcg ttgggcttcg gcaaactggc tgcgatggac gtttccggcg
     4021 ctcagactgt aaaactgtcg ggtggcttca accacggctt caggtttaag cgcggtcgcg
     4081 gcgctgtcga gatagacgcc cgcatcctgt agtgcgggaa actgggcgcg aaactgcgcg
     4141 ggattaaaaa cgttcatggt actcctcggc ttgatgcacc gatcgtgacg caaaattcac
     4201 tttgatacaa ggagagtgct aaccatcaga attatctgga tatcctggcg aagccgcgtc
     4261 agtaacatat gctgaatagt gttaggcgtt aattttagcc tgttaatcaa tactattaag
     4321 atttattaat cgctttaagg agaagatgat gaaaaagact gccgcaatta tttctgcctg
     4381 tatgctgact tttgccctga gcgcctgttc cggttcgaac tatgtgatgc acaccaatga
     4441 cggacgtacc atcgtctctg acggcaaacc acagactgat aacgataccg gtatgatttc
     4501 gtataaagac gctaatggca acaaacagca gatcaaccgt accgacgtga aagagatggt
     4561 cgaactggat cagtaattcg cgatcgcaag gtaaaaaaaa gcaccgcaat taggcggtgc
     4621 tacattaatc actatggaca gacagggtaa atgtacagga agtgaaaaaa ggtagctttg
     4681 ctaccatggt ctgaatcgca gaccaattgc aaacacaaca acacaacatc acaaccgtaa
     4741 gccaaaagtt caccagaaca cgcattccga taaaactttt cgttccggct caggaagtgc
     4801 cgccactata ggtatttgct ggtagaagct caacggacaa tttataatgg ctcagattaa
     4861 aaaaactaat aggttacaca gtgtgatcta attgttaaat tcatttaaca tcaaagttta
     4921 aaagccatgt ctaaacgatt accaccgcta aatgccttac gagtttttga tgccgcagca
     4981 cgccatttaa gtttcactcg cgcagcagaa gagctttttg tgacccaggc cgcagtaagt
     5041 catcaaatca agtctcttga ggattttctg gggctaaaac tgttccgccg ccgtaatcgt
     5101 tcactcctgc tgaccgagga aggtcaaagc tatttcctcg atatcaaaga gatattttcg
     5161 caattaaccg aagcgacgcg taaactccag gcccgtagcg ccaagggggc gttgacggtc
     5221 agtttactcc ccagtttcgc cattcattgg ttggttccgc gactttccag ctttaattca
     5281 gcttatccgg gaattgacgt tcgaatccag gcggttgatc gtcaggaaga taagctggcg
     5341 gatgatgttg atgtggcgat attttatggt cggggcaact ggccggggct acgggtggaa
     5401 aaactgtacg ccgaatattt attgccggtg tgttcgccgc tactgctgac aggcgaaaaa
     5461 cccttgaaga ccccggaaga tctggctaaa catacgttat tacatgatgc gtcacgccgt
     5521 gactggcaga catatacccg acaattgggg ttaaatcata tcaacgttca gcaagggcca
     5581 atttttagcc atagcgccat ggtgctgcaa gcggctattc acgggcaggg agtggcgctg
     5641 gcaaataacg tgatggcgca atctgaaatc gaggccggac gtcttgtttg cccgtttaat
     5701 gatgttctgg tcagtaaaaa cgctttttat ctggtttgtc atgacagcca ggcagaactg
     5761 ggtaaaatag ccgcctttcg tcaatggatc ctggcgaaag ctgctgctga acaagaaaaa
     5821 ttccgctttc gttatgaaca ataatttacg tagggtacga ccatgaccag ccgttttatg
     5881 ctgattttcg ccgccattag cggcttcatt tttgtggctc tgggcgcttt tggcgcgcat
     5941 gtgttaagta aaaccatggg ggccgttgag atgggctgga tccagaccgg cctcgaatac
     6001 caggcgtttc atacgctggc gatcttaggt ctggcggtgg caatgcagcg tcgcatcagt
     6061 atctggtttt actggagtag cgttttcctc gcgttaggca cggtgttgtt cagcggcagc
     6121 ctttattgcc tggcgctgtc ccatctgcgt ttgtgggcgt ttgtcactcc ggttggcggc
     6181 gtgagcttcc tcgcgggctg ggcgttaatg ttagttggtg ctatccgttt aaagcgcaag
     6241 ggcgtaagtc atgaataagg ttgtattgct gtgccgtccg ggctttgaaa aagagtgcgc
     6301 cgcagaaatt accgataaag ccggccagcg ggaaattttc ggttttgccc gcgtgaaaga
     6361 gaatgcgggt tatgtcattt atgaatgtta tcaacctgat gatggcgata agttaatccg
     6421 tgagctgccg ttcagttcat taatttttgc ccgccagtgg tttgtggtgg gggaactcct
     6481 gcagcatttg ccgccagaag atcgtattac ccccattgtc ggcatgttac agggcgtagt
     6541 agagaagggc ggtgaactgc gtgttgaagt tgccgatacc aacgaaagca aagagttact
     6601 gaaattctgc cgtaaattta ctgttccgct acgcgctgcc ttgcgcgatg ccggggtgct
     6661 ggcgaactat gaaacgccga agcgtccggt tgtgcatgta ttctttattg caccaggctg
     6721 ctgctatacc ggttactcat acagcaacaa taattcgccg ttctatatgg gcattccgcg
     6781 cctgaaattt ccggcagatg cgccgagtcg ttccacgctc aaactggaag aggcatttca
     6841 tgtgtttatt cctgcggatg agtgggatga acgcctggcg aacgggatgt gggcggtgga
     6901 tttaggcgct tgccctggcg gctggaccta ccaactggtg aagcgcaaca tgtgggttta
     6961 ttccgtcgac aacggcccga tggcgcaaag tctgatggat accggacagg tgacgtggct
     7021 gcgggaagac ggtttcaaat tccgtccgac gcgcagcaat atctcctgga tggtatgcga
     7081 tatggttgaa aaaccggcga aagttgcggc attgatggcg cagtggctgg ttaatggctg
     7141 gtgccgtgaa accattttca acctcaaact gccgatgaaa aaacgctacg aagaagtgtc
     7201 acacaatctg gcgtatattc aggcacagct tgatgaacat ggcataaatg ctcagattca
     7261 ggcgcggcag ttgtatcacg atcgcgaaga agtgacggtg cacgtccgcc gcatctgggc
     7321 tgcggtgggt ggtcgtcgcg acgagcgata acaggcaagg ccggggcgtc gtctccggcc
     7381 tgctaccctt tccgtcaggc tgttaccaaa gaagttgcaa cctggcgctc atcagaaata
     7441 atgtgcgtta cctcatccag atgcccgatg cgggcttccc ctgaacgatt aaatttactt
     7501 ttatcaatca ataacaacga ttgcgcggca cgttttaata gcatcgattt gtaatcagcg
     7561 ttgatcgcat tggagtccca cagtgcgccg ctgctatcga tcccttcaca agaaaaaata
     7621 aacagatcga tttccagcga tttaagttgg gaaatcagcg agggattgac gtaacagcca
     7681 tatttgcgct caagtgtgcc gccggaactg atcagttgaa tgcgttcgcg tttaccgagt
     7741 tcatggcaaa tcggatggct attggtgaag acctgaatgt tgatgtcagg caactggcgt
     7801 gccagatacc agcaagttga actggcgtct aaggctatca ccatcccttc ttcaatccac
     7861 gcgagcgcct cgcgcgcgat atctgcttta tgcgcataat ggcttttcag cctgatgtga
     7921 aagggatcgc cactgtcttg attttgacgg tggatatatt tagcgcgtcc atgattgcgc
     7981 agaattttac cctgcgtctg taattcattg agatcgcgac gaatggtttc tttactgacc
     8041 tttagctgtt cagagagagc ttccgtggtc aggctggtat ggttcagcag caggtcgact
     8101 atcgcttgct ggcgtgccgc tttcatattt ttcaccccat cattcgataa ccgcccgcgt
     8161 catgcgggcg taccggtatg agattacggt gttacccctt tttttaaaag aatattcccg
     8221 tacttcgctc gttcgcctgt gataacgatc gcaaaggctt tttgcgcccg ttcataaaac
     8281 gcaaaacgat tgatgcggat gatgtcagga cacggggctt gtagtgaaag cgcattacgg
     8341 taacgtcgtt ctacttcagg atcgagagtg tcaccttcta ccgccgccat catcaccagc
     8401 ggcggtgcat aactgtccag ttcaaataac gggataatcg cctggagcaa gtcgctcacc
     8461 aacaggccat cagcgcggat cacctgcggt cccatcgaat gggcgggaaa gtgagcatcg
     8521 gaaaaaataa tttcatctcc atgtcccatc tctgccagca ctttcaatag ttcgggagaa
     8581 attaacggcg aaattgtttt cagcatttca cacttcctct ataaattcag gttcagtttg
     8641 cgggtagaaa taacggtact gataatgaat ctgtgcgcgg gcttcttccg ggctgttaaa
     8701 ttcccctacg ccataccaac cgaacagcgc agctcctgcg acggtcgttt cggcgtcgtc
     8761 gagaactttt accggaatat caagcatatt ggctttaatc tgattccaca atgtgttgcg
     8821 acttcctcca ccgactaaca ataattcaga ggccttaaag tgcccgattt tttccagcat
     8881 ctgtagattg cgctgtaatt gcgcagttaa cccttccagc gccgcgcgat agaaatgccc
     8941 ccgcgtggta ttaagcgtca ctccttgcca gccagcgttc tgacacgaca ataaatcaca
     9001 ctgcattttt acgccatccg cgccaggcgc gatcagacga gcttcttcaa tcaacatttg
     9061 ccagggtgtt tcagccgtcc agaacagttt tctcacccat tccagcacgc cggatgccag
     9121 ccattgcata cctgggttat acaaccctgc ctggctatcc agttcgcagg tggaaccggc
     9181 gtactgactt aacagcgaag tatcaacctg ggcgctacgg accattaaaa tttcccatgt
     9241 accggaagag agcacgggtt cattttggtc ggcaccagcg ccaaaaaggg cgaactgggt
     9301 atcgtgacct gcggaaatca ccggtatgcc aacgggtaag ccgagcattg ctgcggcgct
     9361 gttctgtagc gtaccaatct gttcacccgc ttccaccaga cgagggaaga gtcggcgtgg
     9421 aataccggtg gcttgtaaaa tttgcggact gaaatcgcgt tgctggatat ccagcatctg
     9481 gctggttccg gccatcgtga tatcagtagt gaattcgccg gttaaacggt ggttaatcag
     9541 cgacgaaata aagagccagg cgtgcgcgcg ttccagcagt tgtggatgat tttctttcaa
     9601 ccacaccaac ttatataacg tattgaaact aaaggctccg acgccagaaa tagcctgcaa
     9661 ccgctgtgcg gagatcaact gttcaatatt gtccataacc gctgctgttc gcggacattt
     9721 ccagctaatg atcggataga gcagattgcc ttgcttatct accagagcgc catccacacc
     9781 aaaggtggtg acggcgatac cgcggatgtg gcattcagtc agttcactat tgatttgccg
     9841 acagcaatca gcaaagcgtt gcaaaatggc gtctaaagac cactggtgcc aggtgttgtt
     9901 ttccatcgcg atatcgctgg cattaggcgt tgaggcgcgg gcaacaattt ttccctgccg
     9961 attaaccgcg atggccctga catttgtcgc gccacagtcg agtaccagga taacttcttg
    10021 tttcataatc gctcctgcaa tatagccgga taacattgct tatccggcta accactcttg
    10081 cttgttcagg cccggtagcc ggagcgaccg ggcatcacat cagggagtaa tgtattaacg
    10141 cttatacaac ggaccgtagt tctggcaagc gcggtaatcc tggccttcaa tatccatgcc
    10201 gtgcgcagcc caggcagaag gacgatacac tttggtctct tcaacgttgt gcatacatac
    10261 cgggatacgc agcatggagg cgagagtgat aaagtcagcg ccaacgtggc cgatggtcag
    10321 aaccccatgg ttagcgcccc agttcgccat taccgagtac acatccgtaa acggcccttt
    10381 accggtgagg cgcggtgcaa accaggtggt tggccaggtt gagttggtgc gtttgttgag
    10441 gatgtcatgc acatccttcg gcaattccac gctccagcct tccgcgattt gcagtaccgg
    10501 tcccaggcct ttgatgatgt tgacacgagt catggtgaac gggacgccgc cttcggtaag
    10561 gaagcgggaa gagtaaccgc cgccacggaa gtattcgtgg atcgccgggc accattcggt
    10621 agcggcgagg caagcgtcag cctcttgctg agagatttcc cagtgcggct tcatcgtcgg
    10681 gttaccttcg ctgtcgcgtt gtttacagga accgtccagc gcagcagaac ctgagttgat
    10741 caaatggatg atgccgtgtt ctgccagtcc atcgagttta tgccccgtta cacgctcaat
    10801 tgcttctggt gaccagtagg tacgcacatc ggcaaatacc tgagcggtgc cggtgagctg
    10861 gtgacccatt agcattgcca cgccgttaag actgtcgttt tcggtcgcca cgacaaaggg
    10921 ttcgcgcacg ccattccagt caaatgaact gttgaggatc gcttcggcgg tgtcaccatt
    10981 gggatattga tcggtccagt gacgttgccc ctggaagccc gcagcgatgg cgttgtagcc
    11041 aagtgattct tccacgcgac caatatcggc cagtttgctg ttgccttgca tcatgtcgcg
    11101 gatacacatc gccatcagta aactttcgcg cagaactgcg cggctttgct cggcattgcg
    11161 ttgatactgt ttgttatttt catcttcgcc atagcggaag tttttatcag cccaggccag
    11221 tgccatttcc agttcggctt cgtcgtaaat cttctgatcg atacggcgac gcagttcggt
    11281 catatccacc gcctggactt tcattcccag ccaggattca aagaagttgt gatcaacgat
    11341 ggaaccggcg atacccatcg aaacgccgcc cagcgacaga tagcttttac ctttcatgct
    11401 ggcgacggcc aaaccggcgc gggcaaagcg cagcagtttt tcttcaacat cggcaggaat
    11461 cgatgtgtca tcggcatcct gaacgtcatg accgtaaatg gagaatgccg ggatgccttt
    11521 ctggctgtga gctgccagag ccgctgccag gtaaacagcg ccgggacgtt cagtgccgtt
    11581 aaagccccaa atggctttcg ggcgggttgg atccatgtcg atggtttcac tgccatagca
    11641 ccagcaaggc gttaccgtaa tggtgaggcc tacattctgg ctgctgaatt tttcttcgca
    11701 agcagcggct tcagccatac ccgcgataca ggtatcggaa atgacacact cgacggcagc
    11761 tccgcaggca tggcgcagtt tctcggtcag cagtgcggcc gtagctttcg ccatattcat
    11821 tgtttgttct tcaagcgact cacgaacacc catgcgacga ccgtcaataa ccgggcggat
    11881 accaattttc ggtaagctga tttttttcat tacagattcc tcactttatt cggaaaatat
    11941 gttcagttag ttgccgtttg agaacggaaa cgggcaaaga taaagatgac cgcgaagcag
    12001 agtgcgggga tcagttcagc agtggggatg ttgcccgccg cgtcactgac aaaacccatg
    12061 accggagtga caataccgcc gccaatgatg gtcataacga tgaaggacga accgtatttg
    12121 gtgtcctggc cgagattctt aatgcccagc gagaagattg ttgggtactg aatcgacata
    12181 aaggcgctgc ataaagtcag ggctattaag cccacatgac cgccagcgaa ggctgagatc
    12241 aggcacagtg ccatagcgat taatgcgtag gcggccagga ctttgtgtgg tgcgaagcga
    12301 ctgatgagcc aggtaccggt gaaacgacca ataaagaagc acaccatggt tccggttaaa
    12361 tagttagcgg caaagccggc agtcatacct ggaatttctt ctacagcgta gcgaatcaaa
    12421 tagctccagc aggccgtttg tgcgccgaca tagcagaatt gcgctaatac cgcccagcgc
    12481 cagtgacgaa tacgcgccag acgagaaagc gatgcggaga acgagccttg tttggcgtca
    12541 ctgtgattat cactctgcaa tgccgggaat ttcgtcagca tgatcagcag ggcgaccagt
    12601 aacacgatag ccacgatgat catataaggt gtctgtaccg ataataccag gctgtgttta
    12661 tacgcactca attgctctgg agacatttta tcgagaacgt cttgcgattg atgtggcacg
    12721 ttagacaaaa taagactttg cccaaagaca accgcgataa ttgcgccaaa cgagttaaat
    12781 gtttgcgcaa gatttaagcg gaagtgacca ctgctttctg gccctaatac cgtaacaaaa
    12841 gggtttgcgg cagtttccag acaacctaat ccggctgcaa taataaatag gccaactaaa
    12901 aataaggtgt agttcattat ttctgcagcg ggccagaata atgcagcgcc caaggcatat
    12961 aaaaataatc cggtaataat ccctgcttta taactgagtt ttttcatcaa tatcccagca
    13021 gggattggga taatgaaata accaaagtaa aaggccgatt ggatcaggcc agcctggaaa
    13081 tttgtcagcg taaaagcctg ctggaattga ggtaataaaa tgtcgttaag gttattggct
    13141 accgcccaaa gaaaaaacag tgagcacagc agcgcgaatg gaataatgta acttctgctt
    13201 tgccctgcat ctttatctac cgcacggtaa ctctgcgttt gtattgatgt gtttcccata
    13261 gcatcctctt aggttcagaa gcttaagcac gtaatcggtt atgttttcaa aagtgcaaaa
    13321 ccagcgagtt cgggcttcat atcagtgaat atttgcctgt ctgaaatgaa ctcatggatt
    13381 cattttcaaa taaaaaacgc tctgtaatat gacggcggtc acacttatta gctggaaggt
    13441 gactttatgt gactaccatc actttaataa tcgaaatttc atgcccgttt cagaaaataa
    13501 atcataaaaa acacaaacca gatgaccgta ttaattgttt atgccgaaaa cgggcattcc
    13561 tggcttgggt gaatagaaaa atgaccgttt tgataaatat ttttaagagc ggtcattttt
    13621 aatggggtta taaaaagaga acttgcagtt atttactgtg attagttgaa ccaggtcaca
    13681 aaatataagc ttgtgaattt ctttcttgtt aatcaggaag aagatggtgg gtaattaaac
    13741 ggctaattca atagtgtgaa aggaacaaca ttattgccct gttttgaatc agagagaggt
    13801 agctaatgga acgaaataaa cttgctcgtc agattattga cacttgcctg gaaatgaccc
    13861 gcctgggact gaaccagggg acagcgggga acgtcagtgt acgttatcag gatgggatgc
    13921 tgattacgcc tacaggcatt ccatatgaaa aactgacgga gtcgcatatt gtctttattg
    13981 atggcaacgg taaacatgag gaaggaaagc tcccctcaag cgaatggcgt ttccatatgg
    14041 cggcctatca aagcagaccg gatgccaacg cggttgttca caatcatgcc gttcattgca
    14101 cagcagtttc cattcttaac cgaccgatcc ccgctattca ctacatgatt gcggcggcag
    14161 gtggtaattc tattccttgc gcgccttatg cgacctttgg aacacgcgaa ctttctgaac
    14221 atgttgcgct ggctctcaaa aatcgtaagg caactttgtt acaacatcat gggcttatcg
    14281 cttgtgaggt gaatctggaa aaagcgttat ggctggcgca tgaagttgaa gtgctggcgc
    14341 aactttacct gacgaccctg gcgattacgg acccggtgcc agtgctgagc gatgaagaga
    14401 ttgccgtagt gctggagaaa ttcaaaacct atgggttacg aattgaagag taatttcgta
    14461 aagcaacaag gagaaggatg atggctaaca gaatgattct gaacgaaacg gcatggtttg
    14521 gtcggggtgc tgttggggct ttaaccgatg aggtgaaacg ccgtggttat cagaaggcgc
    14581 tgatcgtcac cgataaaacg ctggtgcaat gcggcgtggt ggcgaaagtg accgataaga
    14641 tggatgctgc agggctggca tgggcgattt acgacggcgt agtgcccaac ccaacaatta
    14701 ctgtcgtcaa agaagggctc ggtgtattcc agaatagcgg cgcggattac ctgatcgcta
    14761 ttggtggtgg ttctccacag gatacttgta aagcgattgg cattatcagc aacaacccgg
    14821 agtttgccga tgtgcgtagc ctggaagggc tttccccgac caataaaccc agtgtaccga
    14881 ttctggcaat tcctaccaca gcaggtactg cggcagaagt gaccattaac tacgtgatca
    14941 ctgacgaaga gaaacggcgc aagtttgttt gcgttgatcc gcatgatatc ccgcaggtgg
    15001 cgtttattga cgctgacatg atggatggta tgcctccagc gctgaaagct gcgacgggtg
    15061 tcgatgcgct cactcatgct attgaggggt atattacccg tggcgcgtgg gcgctaaccg
    15121 atgcactgca cattaaagcg attgaaatca ttgctggggc gctgcgagga tcggttgctg
    15181 gtgataagga tgccggagaa gaaatggcgc tcgggcagta tgttgcgggt atgggcttct
    15241 cgaatgttgg gttagggttg gtgcatggta tggcgcatcc actgggcgcg ttttacaaca
    15301 ctccacacgg tgttgcgaac gccatcctgt taccgcatgt catgcgctat aacgctgact
    15361 ttaccggtga gaagtaccgc gatatcgcgc gcgttatggg cgtgaaagtg gaaggtatga
    15421 gcctggaaga ggcgcgtaat gccgctgttg aagcggtgtt tgctctcaac cgtgatgtcg
    15481 gtattccgcc acatttgcgt gatgttggtg tacgcaagga agacattccg gcactggcgc
    15541 aggcggcact ggatgatgtt tgtaccggtg gcaacccgcg tgaagcaacg cttgaggata
    15601 ttgtagagct ttaccatacc gcctggtaaa tgcgctgatg tgataatgcc ggatacgacg
    15661 tttgcggcgt atccggctcg ccgttaccgt accaaccgca attgctgtaa attgccgtcg
    15721 atatgcaaat cggtttgtaa gcgggcaata tcgcggcaca gaaacgccat ctctttatgg
    15781 gtttctaatt ttttgcgcca cttttcggca accgcatcca gattctcata tatcccttcc
    15841 agactctgaa actcgaccag cagctgcgtg gcgctttttg gtccgattcc cgcaacaccc
    15901 ggtacctttg aactgctgat ccccgcaagt ccccagtaat cgggcaactg ctgcggttga
    15961 acgccaaatt ctttatcgat aaatggcgca tccagccaac gtttctggaa gtaatcacga
    16021 atacgtaatg tcggtgaaag taactgacag tagcctttat ctgtcgaaac aatcgttgcc
    16081 tgatgcccgg cctgtgtcac tttgaccgcc agcgtggcgg ctaagtcatc ggcttcgttg
    16141 ccgctggttg accagcacgg gacgccgcgt tgctcaaagg cggcgcgtaa tgcaggcatc
    16201 tcgtcgtgca actcttccgg cattggcggt cgacccgctt tgtaatctgg taaacgctga
    16261 tgacgccagc cgctactgcg gttttcatca tcaaaaacgg cgaccgcgtg ggttggctgg
    16321 ctgtgcataa tgagctgatc gagcgcatgc tggcaggttt cgacacaggg cgatccctga
    16381 acggcatgaa tgcgacgaat aagattcagt gcatcgacaa taagcaaatg aacagccacg
    16441 ataaccccct taaagatcag gcgataaggg taacattcga tgccggaaca ggctacggct
    16501 ggatgagaaa tcgggaagag gcctcgcaaa acgaggcctc tggagagcga ttaatcgcag
    16561 gcaacgatct tcattgccag gccgccgcga gaggtttcgc ggtacttggc gttcatatct
    16621 ttacctgttt cgtacatggt ttcgataact ttatcgaggc agacgcgcgg ctcgctggta
    16681 cggcgtagcg ccatacgtgc ggcgttcacc gcttttactg ccgcaatggc gttacgctcg
    16741 atgcatggca cctggacctg tccggcgacc gggtcacacg tcagaccgag gttgtgctcc
    16801 atggcgattt ccgccgcgat gcacacctgc gccgggcttg cacctaacag ttctgccaga
    16861 ccagccgccg ccattgagca cgccacacca acttcaccct ggcagccgac ttcagcacca
    16921 gaaattgacg cgttcatctt ataaagagaa ccaatggcac tggctaccag caggtaacga
    16981 gccagtgagt tagcgttcac ttcgcggata aacttatcgt agtacgccag cacagccggg
    17041 ataatcccgc acgcaccgtt agtcggcgca gtcaccacgc gaccgccagc ggcgttctct
    17101 tcgttcactg ccagtgcaaa catgttgatc cagtcaacaa ccgccatcgg gtcagtggtg
    17161 gttttatcct ggctgaccag catccggcgt agtgccgcag cacggcgtgg tacgcgcagt
    17221 ttgccaggca acacgccttc ggtagaaata ccgcgctcaa taccgccgcg catgacttcc
    17281 cagacgttcg ccaggtgctg ttccagctct tctttgctgt gcagcgccag ctcgtttttc
    17341 atcatcaggc cagagagtga cagcccggtt tcctgacaat gtttttgcag atcggctgct
    17401 gaactgtacg gataaggaac ttcaaccggt gcgctattct gctggccaaa atgctcttca
    17461 tcaacgataa agccaccgcc aatagagtag taagtctggc tgtaaacgac tttatcgccc
    17521 gccagcgcgg taatgcgcat accgttttca tgcagagaaa ggttgtctgc atggaagttc
    17581 atgcactgat caaccgggaa ctccacttca tgctgaccgt ttgccagcat caggcgacca
    17641 tgagtattca catcctgaat aaaaccaggg atggaatcga tatccacggt atccggcagg
    17701 ttacccgcca ggcccataat aatggcgata tcagtgtggt gacctttacc ggtcagagag
    17761 agcgagccgt acacgtcaac caccacgcgg gtcacgtctt taagcagatt acgggcaatc
    17821 agatcgtcgg taaattgttt acccgctttc attggtccaa cggtatgaga actggaaggg
    17881 ccaatgccga ttttgaaaat atcgaatacg ctaatcatag gaaatacatc gcgttaaaac
    17941 ggaggaagcg ccgcccgaaa gcggcgcgaa aggacttagc tgaacagaga gtagaagatt
    18001 gcggagattg caatcagacc catcacgaca acgaatacgt tgctgatgtg accgctgtac
    18061 ttacgcattg ccggtacttt ctgaattgcg tacatcggca tcaggaacag gatcatcgcg
    18121 atgattgggc cgcccagggt ttcaatcata cccaggatgc tcgggttcag ggtggcaaca
    18181 atccaggtcg ttaccagcat gaacagcgca gtgatacggt tcagcttgtt gatttcgata
    18241 gacttacctt taccacgcag agatttaatc accataccgt tgaagccttc acgtgcgccc
    18301 aggtagtggc cgaggaagga tttggtgata gcgataatcg cgataatcgg agccatccac
    18361 gcgataaccg gtgcgttaaa gtggttagcc aggtaagaca gaatcgagat gttctgctct
    18421 ttagccgcag ccaggtctgc cggagtcagg ctcagtacgc agctgaagac gaagaacatt
    18481 acggtcagca ccatcatgat gtgtgcgaat gccaggatct tcgagcattt ctgttctgcc
    18541 atatcgccgt actcttcacg cttcgcaacg gcgaaagaag agatgatcgg agagtggttg
    18601 aacgagaaca ccattaccgg aattgccagc cacagggtca tccacagacc gtttccggtt
    18661 gcagatgcag tgtccagaga cagcgtttcc agtgctgcgc cgttccactg cgggatcagg
    18721 tacagagcca gcagcatcag tacgccaaca aacgggaata ccagaatact catcgcttta
    18781 acgatcatct gctcaccaaa gcgaacgatg gtcatcatac ccacgatcag gatcagcgac
    18841 agaatcgcac gcggcggtgg cgtcataccc agctggtgag acatgaagct ttcaactgta
    18901 ttggtgattg ccacgctata aaccagcagg atcgggtaga tagcgaagaa gtagagcagg
    18961 gtaatcagtt tacctgcgcc aataccaaag tgttcttcta caacctcggt gatgtcttcg
    19021 cccgggtttt taccagacag tacgaagcga gtcaggccgc ggtgagcaaa aaacgtcatc
    19081 gggaacgcaa ggatagccat gatgatcagc gggatcatac cgccaacacc ggcgttgatt
    19141 ggcaggaaca gcacgcccgc gccgattgcc gtgccgtaaa ggcccagcat ccacatggtg
    19201 tctgtcttgc gccaggcact acgagagtct ttcgacgcaa tcgtgctggt ttgagtcgtt
    19261 tccatctatt tctcctggag gaatgcaaat aattcagctt ttagccagtt cagcccggga
    19321 aggtgcctga ccgtaaaaat gaaatctgtc tatcggcgat ggcttaatca tttaccgccg
    19381 taataatttg agggcggaaa gatacacaca agttatgtat ctatcagtga tcttgatctc
    19441 aaatacaata atctacttgg aagatagatt atcccaacgc tttactctgt aaatcaaaag
    19501 taaaagagaa tttaagggca atatttgccc attaaacgac atctgacttc ttccggggcg
    19561 cgcaatatat gtaggttgaa ctgaaaaaat caatactttt agttaatcat ggcgataatt
    19621 tctttttcat agcgataaaa tacggtttat gaaaataggg aaacgtttgc gttgcaacat
    19681 aaattgtatg acatattaac tgtgatgata tttgtcgcgt gagggtggta agaaacattc
    19741 atataacaaa tgaaatgagt tgatgagtaa gtgaccaaaa acgagaaaac ccggcaacaa
    19801 acgtcaccgg gggagcggag attacgtgca gatttcgtag caagggatgt aggctgagcc
    19861 tggcaacttc atacgatgct gggcaacaaa accctgtagc aggtcgtcca tacgacgcat
    19921 aatctcttta tcgccgttga ttttgtaagg accaaactct tcaatggcgc gaataccgac
    19981 ttcttttacg ttacccgcca caataccgga gaacgcacgg cgcaggtcgg cagccagcac
    20041 ttcaacaggt tgatccgggc aaagcttcag attagccata ttctcgtgag acggctcaaa
    20101 cggcatttgc aaatctggtg caatgcgcat tgaccagtta aagctgtaag cgtcaccagt
    20161 gtcgcggcga ttttctttca ccagcggcat cgattttttc atctgacgag cgacttcagc
    20221 ggcgtcatca atgatgatgc ggtaatggcg gcgcgcgttt tcgcccagcg tatgtacgac
    20281 aaactcgtcc agtacgcgga agtagtcggc gctctctttc gggccggtga ggatcaatgg
    20341 taaaacctga tctttgttgg ccgggttcat taaaattccc agcaaataca gcaactcttc
    20401 tgccgtaccc acacctccag ggaagataat gatgccgtga gcgatacgga caaacgcttc
    20461 cagacgtttt tcgatatccg gcatgatgat caattcgttg accagcgggt taggcggttc
    20521 agcggcgata atcgacggct ctgtcatacc aataaaacga ctgtctttgt aacgctgctg
    20581 cgcgtatccg accgcagcac ctttcatcgg cgcttccatc gctcccggac cacagccggt
    20641 gcagatattc agctcacgca ggcccagctg gtttccgacg cgacgggcat acaaatactc
    20701 gttttcgtta attgagtgac cgccccagca gaccaccata tttggcgctt cacccacatg
    20761 caacgcgcga gcgttacgca agatggaaaa gaccaggtta gtgatgtgga cggagttgtc
    20821 gagattcagg ttgggaaaac gaacggtatt atggatttgc ccgtaaacga agagaatgtc
    20881 tcgcagaacc gcgaacaagt tggcctgcaa agcgcgaata attcgcccat cgacaaaagc
    20941 ctcttccggg ggattaatca gttccagctt tacgccgcgt tcacggcgca ggacgttaat
    21001 atcgaaattt tcaaaacgag acagcaattc tttgctgtta tcggtcaaac taccggagtt
    21061 cagtacggca agtgaacagt tgcgaaacag ttgatagagg tcgctgctgg cggtgcgttt
    21121 aagcatatcc acttccagct gcgacaacat atccatggag ccaagcgggc taatatgtgt
    21181 aatcaagaaa aactccttat gggacgaata tcgtcattcc ctttgattac aatagccctg
    21241 cctgatgacc tttcacaacc ttctgcgtga atccagcacg caaaattgag aaaaaattta
    21301 ttgccgaacc agtcttgtgg tcgatgggac aaaatcgcta ttactgcgcc acgggttaat
    21361 gtccagaccg ccacgacggg tataacgtgc gtaaacgctt aatttctctg gctggcagaa
    21421 gcgtaacagg tcattaaaga tgcgttccac gcactgttcg tggaactcgt tgtgatgacg
    21481 gaatgagacc aggtaacgca gcagtttttc tctgtcaatt tggcgtccac gatactgaat
    21541 ttggatcgaa ccccaatctg gttgatgggt gatcaggcag tttgatttca gcaggtggct
    21601 gacaagcgtc tcttcctcta ctttttcacc gctggtggca ttctccagat agtcagtagt
    21661 gaattcatag ttatcgatag tgatatcctg gtcatcaatg caggtgccat tgaaatgacc
    21721 tatcggctgg ccttccagtt catcaagacg atataacgcc acgctaacct taccctgggc
    21781 gcaagtgctt aagtcgcgct ccagcgtctg gcgcacctca tcccagttat taaaacgcgt
    21841 ctggttaaaa ctgttgagat agagcttaaa actcttcgac tcaatcagat ttacgctggt
    21901 gtaatcaagt tcaacatgac cgacagcgac ctgcggcaaa cctttcgcat tcagccagga
    21961 aagttcatac agcgtccaga tatccgtacc gtgaaaaggc aggttatccg ctttcagacc
    22021 cagcgggtcg cgattcaggc tgcgtggaac gccttgcagt aggctggcgt cataggtatc
    22081 ccggtaatcg gttgattttc caagagtcag gcccgcaagt gcctgatggt ttgcataaga
    22141 agacatgttt caccgtcata aaccagataa actaaacgac aagtgtatct ggtttaagtg
    22201 aagagagaaa ttagtggacg atttgaccgc acaagccctg aaagatttta ctgcacgcta
    22261 ctgcgatgcg tggcatgaag agcataaaag ctggccgtta agtgaggaac tgtacggtgt
    22321 tccttcaccg tgcattattt caactaccga agatgccgta tactggcaac cccagccgtt
    22381 taccggggaa caaaatgtaa actcggttga acgcgctttt gatattgtga tacaacccac
    22441 aattcatacc ttttatacga ctcagtttgc cggggatatg cacgcgcagt ttggcgatat
    22501 caaactgaca ttgctgcaaa cctggagtga agacgacttc cgtcgggtgc aggaaaatct
    22561 gattggtcat ctggtgactc agaaaaggct aaaactgccg cccacgctat ttatcgcgac
    22621 gctggaagaa gagttagagg tcatctcggt gtgtaatctc tccggtgaag tgtgcaaaga
    22681 gacgctggga acacgtaaac ggacgcattt agcctcaaat cttgcggaat tccttaatca
    22741 acttaagcct cttctgtaat ccaaataccc catctggttg tgagagatct cttacagact
    22801 ctgtaggaga tcgccaggaa ataagcgaat acttaaaaag ataagaatcg ttattttcat
    22861 ttaaaatcaa aatgttgatt gttaattctt aactttcata tgaaattttc cttaaggcat
    22921 tgtctgtaag cgccttgtaa gacttcgcga aaaagacgat tctatcttcg tcgacaggga
    22981 gtcagacaac gaagtgaaca tcaggatgat gacacttctg caggacacac caggatggtg
    23041 tttcagggaa aggcttctgg atgaagcgaa gaggatgacg caggacgcgt taaaggacac
    23101 ctccaggatg gagaatgaga accggtcagg atgattcggt gggtcaggaa ggccagggac
    23161 acttcaggat gaagtatcac atcggggtgg tgtgagcagg aagcaatagt tcaggatgaa
    23221 cgattggccg caaggccaga ggaaaagttg tcaaggatga gcagggagca acaaaagtag
    23281 ctggaatgct gcgaaacgaa ccgggagcgc tgtgaataca gtgctccctt tttttattcc
    23341 tgctatcctt cgcggcagtt tttcttattg aggttgcttt atgaccactc atgaccgcgt
    23401 tcgtctccag ttgcaggcgc ttgaagcgtt actgcgtgaa catcagcact ggcgaaacga
    23461 tgaaccccag ccgcatcaat ttaatagtac ccaaccgttc tttatggaca ccatggaacc
    23521 actggagtgg ttgcagtggg tgctgatccc gcgaatgcac gatttgttag ataacaaaca
    23581 gccgttaccg ggcgcttttg ccgttgcacc ctattatgaa atggcgctgg cgacggacca
    23641 tccgcaacgc gcgcttattc tggctgagct ggaaaaactg gatgctcttt ttgcggatga
    23701 tgcgagctaa tgctggaaat actctatcag gatgaatggc tggttgcggt aaataaaccc
    23761 tccggctggc tggttcaccg cagctggctg gatcgcgacg agaaagtagt ggtcatgcaa
    23821 accgtgcgtg atcagattgg ccagcacgtt tttaccgctc atcgtctgga ccgacccact
    23881 tctggtgtgt tgttgatggg attatccagc gaggccggac ggctgctggc acaacagttt
    23941 gaacagcacc aaatccagaa acgttaccat gcgattgtgc gcggctggtt gatggaagaa
    24001 gcagttctgg attatccact ggtggaagaa ctggacaaaa tcgctgataa atttgcccgc
    24061 gaagataaag gctcgcagcc agcagtgacg cattatcgcg gtctggcgac cgtagaaatg
    24121 ccggtagcga ccggacgtta cccgaccacg cgctacggcc tggtggaact ggagccgaaa
    24181 accggacgca aacatcagct tcgccgacat cttgcccatt tgcgtcatcc gattattggc
    24241 gatagcaaac atggcgattt acgccagaat cgcagcggtg ctgagcattt tggcctccag
    24301 cggttaatgc tacatgccag tcagttgtca ttgacgcatc cttttactgg cgagccgctg
    24361 actattcacg cgggcctgga cgacacctgg atgcaggcgt tatcacaatt tggctggcgc
    24421 ggtctgcttc ctgaaaatga aagggttgag ttcagtgcgc catcgggtca ggatggagag
    24481 ataagttcct aatccaggga gaaaacggta tggcggaaat tggtattttt gtcggcacca
    24541 tgtacggaaa ttcgctgtta gtggcggaag aagcagaagc aattctgacc gcacagggcc
    24601 acaaagcaac ggtatttgaa gatcctgaat taagcgactg gctgccttat caggataagt
    24661 atgttctggt ggttacgtcc acgaccgggc agggcgacct tcctgatagc attgtgccgc
    24721 tctttcaggg aatcaaagat agtctgggct tccagccgaa tctgcgttat ggcgtgattg
    24781 cgctcggcga cagcagttat gtaaatttct gcaatggcgg caaacagttc gatgccttgt
    24841 tgcaggaaca gagcgctcag cgggttggcg aaatactgtt gattgacgcc agtgagaacc
    24901 cggaaccgga aacggaatca aatccgtggg tcgaacagtg gggcacgctg ttgtcctgat
    24961 atgttcagcg agcggtaaat gtcgttttag cggtgctgaa tcgaatattt tcaggcaaat
    25021 gccagtaaaa actgcttcat agcgcggatt tttactggcg ttggcctgga gtcaagcgat
    25081 ccatttcata ctcttcttta tttcttcgtt ttaacccttc ctttcttgtt cttgttttca
    25141 tttccgtgaa gtggattcca ccgtccaggg ctaatgccaa aatcgggcct cattgaacgc
    25201 attaatgttg tgttgttgca cggtgagccg ctatggcgcg ctttttatac tgctattgcc
    25261 agatataaac acgcgccgta ttcggcgaac gacctataaa aacggcaaaa aacaccctac
    25321 gtcacctctg atttcctggc tatgtcgcag tccagagtga gcgtggctaa cgcgaatttt
    25381 caggagtgca acaatgagtt ctttaagtca ggctgcgagc agtgtggaaa aacgcacgaa
    25441 tgctcgttac tggatagtgg tgatgttgtt tatcgtcaca tccttcaact acggcgaccg
    25501 cgctacgctt tctattgccg gttcggaaat ggccaaagat atcggccttg atcccgtggg
    25561 aatgggctat gtgttctctg ccttctcatg ggcttatgtt atcgggcaga tccctggtgg
    25621 ttggttgctg gatcgttttg gttcaaaacg cgtctacttc tggtcgatct ttatctggtc
    25681 gatgtttacc ttgctgcaag gcttcgtcga tatctttagt ggattcggca ttatcgttgc
    25741 cctgtttact ctgcgcttcc tggtcgggct tgctgaagcg ccatctttcc ccggcaacag
    25801 tcgcattgtt gcggcctggt ttccggcgca ggaaagggga acggcggtgt cgatttttaa
    25861 ctccgctcaa tacttcgcaa cggtgatctt cgcgccgatt atgggctggc tgacgcatga
    25921 agtgggctgg tcacacgtct tcttctttat gggcggtctg gggattgtca tcagctttat
    25981 ctggttgaaa gtcatccacg agccaaatca acatccgggg gtaaatcaga aagagctgga
    26041 gtacatcgcc gcgggtggcg cgctgatcaa tatggatcag caaaacacca aagttaaagt
    26101 gccgttcagc gtgaagtggg ggcagatcaa acaactgctc gggtcacgga tgatgatcgg
    26161 cgtttatatc ggtcagtact gtatcaacgc cctgacttac tttttcatta cctggtttcc
    26221 ggtttatctg gtgcaggcac gcgggatgtc gattctgaaa gcgggctttg tggcttccgt
    26281 tccggcggtt tgcggtttta tcggcggtgt gctgggtggg attatttccg actggctgat
    26341 gcgccgcacg ggatcgctga acattgcgcg taaaacaccg atcgtaatgg gcatgttgct
    26401 gtcgatggtg atggtgttct gcaactacgt caacgttgag tggatgatca tcggctttat
    26461 ggcgctggcc ttcttcggta agggcatcgg ggcgctgggt tgggcagtaa tggcagatac
    26521 cgcgccaaaa gagatcagcg gtctttccgg tggcctgttc aacatgttcg gtaacatttc
    26581 tggcatcgtc acgccaatcg caattggtta tatcgttggc acgactggct cctttaatgg
    26641 ggcgctgatt tatgttggtg ttcatgcctt aatcgcggta ctgagctacc tggtgctggt
    26701 gggcgatatc aagcgtatcg agctgaaacc tgttgcgggg caataagatg gcgacacaat
    26761 ccagtcctgt tattactgat atgaaagtca ttccggtggc cgggcatgac agcatgttgc
    26821 ttaatattgg tggggcacat aacgcatatt tcacccgcaa tattgtggta ctcaccgata
    26881 acgccgggca taccggcatt ggtgaagcgc cgggcggaga tgtgatttat cagacgcttg
    26941 tcgatgctat tccgatggtt ctgggccagg aagttgcgcg actgaataaa gtggtccagc
    27001 aggtgcataa aggtaatcag gccgccgatt ttgatacctt cggtaaaggt gcctggacct
    27061 ttgaattacg cgttaacgcc gtggcggcgc tggaagccgc tttgcttgac ctgctaggta
    27121 aggcgctgaa tgttccggtc tgcgaactgt tagggccagg caagcaacgc gaggctatta
    27181 ccgtcctcgg ttatctgttt tatatcggtg atcggaccaa aaccgatctt ccttatgtgg
    27241 aaaatacgcc gggcaaccat gagtggtatc agttgcggca tcagaaagca atgaacagcg
    27301 aagccgttgt gcgtctggcg gaagcctcac aggatcgcta cggctttaaa gatttcaaac
    27361 ttaagggcgg cgtgttacct ggcgagcaag aaatcgacac tgttcgtgca ttgaagaaac
    27421 gcttcccgga tgcgcggatt accgttgatc ccaacggtgc atggctgctt gatgaagcca
    27481 tttctttatg caaagggctg aatgatgttc ttacctatgc cgaagatcca tgcggcgcag
    27541 aacagggctt ctccggacgt gaagtgatgg cggaatttcg acgggcgacc ggcttgcccg
    27601 tcgcgactaa catgatcgcc accaactggc gcgaaatggg tcatgcggtg atgctcaatg
    27661 cggtagatat tccacttgcc gatccgcact tctggacgct ttccggtgca gtccgtgtgg
    27721 cgcagctttg cgacgactgg gggctgacct ggggctgcca ttctaataac catttcgata
    27781 tctctctggc gatgtttacc catgtgggcg cggcggcacc gggtaatcct accgctatcg
    27841 atacccactg gatttggcag gagggcgatt gtcgcctgac ccaaaatccg ctggagatta
    27901 aaaacggaaa aattgccgtt cctgatgcgc ccggtctggg cgtggaactg gactgggaac
    27961 aggtacaaaa ggcacatgag gcctataaac gtctgcctgg cggtgcgcgt aacgacgcag
    28021 gtccgatgca gtacctgatc cccggctgga cctttgaccg taaacgtccc gttttcggcc
    28081 gtcattgatt ctgaaaaagg acataaatat gagttctcaa tttacgacgc ctgttgttac
    28141 tgaaatgcag gtcatcccgg tggcgggtca tgacagtatg ctgatgaatc tgagtggtgc
    28201 acacgcaccg ttctttacgc gtaatattgt gattatcaaa gataattctg gtcacactgg
    28261 cgtaggggaa attcccggcg gcgagaaaat ccgtaaaacg ctggaagatg cgattccgct
    28321 ggtggtaggt aaaacgctgg gtgaatacaa aaacgttctg acgctggtgc gtaatacttt
    28381 tgccgatcgt gatgctggtg ggcgcggttt gcagacattt gatttgcgta ccactattca
    28441 tgtagttacc gggatagaag cggcaatgct ggatctgctg gggcagcatc tgggggtaaa
    28501 cgtggcatcg ctgctgggcg atggtcaaca gcgtagcgaa gtcgaaatgc tcggttatct
    28561 gttcttcgtc ggtgatcgca aagccacacc gctgccgtat caaagccagc cggatgactc
    28621 atgcgactgg tatcgcctgc gtcatgaaga agcgatgacg ccggatgcgg tggtgcgcct
    28681 ggcggaagcg gcgtatgaaa aatatggctt caacgatttc aaactgaaag gcggtgtact
    28741 ggccggggaa gaagaggccg agtctattgt ggcactggcg caacgcttcc cgcaggcgcg
    28801 tattacgctc gatcctaacg gtgcctggtc gctgaacgaa gcgattaaaa ttggtaaata
    28861 cctgaaaggg tcgctggctt atgcagaaga tccgtgtggt gcggagcaag gtttctccgg
    28921 gcgtgaagtg atggcagagt tccgtcgcgc aactggcctg ccgaccgcaa ccaatatgat
    28981 cgccaccgac tggcggcaga tgggccatac gctctccctg caatccgttg atatcccgct
    29041 ggcggatccg catttctgga cgatgcaagg ttcggtacgt gtggcgcaaa tgtgccatga
    29101 atttggcctg acctggggtt cacactcaaa caaccacttc gatatttccc tggcgatgtt
    29161 tacccatgtt gccgccgctg caccgggtaa aatcaccgcg attgatacgc actggatttg
    29221 gcaggaaggc aatcagcgct tgaccaaaga accgtttgag atcaaaggcg gtctggttca
    29281 ggtgccggaa aaaccggggc tgggtgtaga agtcgatatg gatcaagtga tgaaagctca
    29341 tgagctgtat cagaaacacg ggcttggcgc gcgtgacgat gcgatgggaa tgcagtatct
    29401 gattcctggc tggacgttcg ataacaagcg cccgtgcatg gtgcgttaag acagaaaacc
    29461 aaaaccggct ctatctggag ccggcttgag actgatgcta aacgcaaaat agcctgttgt
    29521 gctatgtatc aggtctacat cattttttaa ttcattgaat ttaattggtt ttgtaggccg
    29581 gataaggcgt taacgccgca tccggcataa acacaggcac tttgtcacca atctgaaacc
    29641 agcgtcataa aaagccgatt gctactcgac aagacgtccg ttacccgaga attttgctgg
    29701 cttcgcgcgc tacattatcc atctcgtcca acagttccag cagctccggc tccaaatctt
    29761 cttctttagt accgctacgt agctgttgtt cgatcagttg gcagagattc ttcatacgcg
    29821 gcacaccgct atagccgcaa ctgccatgca gtttatgaat caaatcaacc aggccttccg
    29881 ggttttctcc aaccagctgt tcctcaactt tgttgcgaac ttcaggcagg aaatcgagta
    29941 acatttgcag catatcgcgc gctaaatcgg tttttcctgc tgcctggcgt agtgccagtt
    30001 gccagtcgag ggtcgcattc gggttcacca caatttcgtt gacttcgggc gtcacgacgc
    30061 gagaggaaat accgctgcca ggcttgtagc gcaacaacaa attatgcaat cgctcttctt
    30121 caatcggttt cgccagataa tcgctcatcc ctgcgccaag cagcttctct ttttgcccgg
    30181 ccattgcatg cgccgttacc gcgataaccg gcgtttgttg ctgatggggg agctggtgga
    30241 tgagctcgca ggcccgaatg ccatccatgt caggcatttg aatatccatt aagatcaaat
    30301 cgaacggcat ctgtttcgcc cgttcaaccg cctgatgccc gctatcgcaa agttccacat
    30361 gttgcaccat atcttccagc aatgcgccga taagtttcag gttagcgggg ttgtcatcaa
    30421 ctgccatgac tgtcattgcc agcttgcttt catcggttac aggcaaaagc gtgttttgtt
    30481 tgtgatgaca aaattccgtc agggcaggca acaggcgcgt aggtgttaat ggtttcagca
    30541 gacacgcgcc gataccatct tgcttgagtt tttctgcatt gacttgtgca tggcaaggaa
    30601 gtgccagcat caggaaatcg gtcatcgata ccgctttcgc taatcgctca tgttgcattg
    30661 ttagcggctc gcggaaggtc accgcgatgc ctaacaacat catgtcgtaa tgcgcgggag
    30721 gcagcgcgga gaacgttggg ctataaacca cttccagcgg cgtttcactt aaaatatcca
    30781 gcgtgcattg cgctgctgcg gagtttggtt cgacataggc caggcgctta ccggcgaggc
    30841 actgggtgga tggcccttcg ataataatgt tcgggttcag atcgagatta atgtggaacc
    30901 agaaagttga accgcgattc ggctggctat ggaacgaaat atcgccgccc atttcattaa
    30961 ccagtttttg tgtaatcacc agccccagac cggtgccacc atgacggcgg gaaatactgg
    31021 catcagcctg tcggaaggcc tggaataagc gcgattgatc gcgttcagga ataccaatgc
    31081 cggtatcccg aatctgcact tcaatctgca ctttggtatt actcagcgca cgtttttcta
    31141 ccagaatatc aatgttgcca ttctcggtga atttaattgc attccccacc aggttagtga
    31201 tgatttgctg taatcgcagt gggtcgccga tcacgttatc aggcacgtcg cttttaatat
    31261 tgagcgtcag ttccaaccct ttatcgtgag aagaatgtgc cagcagagta acgacttcat
    31321 ccagcgtgct gcgtagtggg aatggaatac tttccagaat cagcttacct gcttccagtt
    31381 tcgagaagtc gagaacatca ttaataattg ccagcaaatt atttgccgaa cgttcaatcg
    31441 tattcaggtg atcgcgctgc gttggtgtta attctgtttt cagcgtcagg cgggtaaagc
    31501 caataacacc attcagtggt gtacgcagct cgtgtgacat atttgccaga aactcggatt
    31561 taatacgcgc cgcttcctgg gcgcgctttt tcgccagatc taactcaacg ttctgaattt
    31621 ccatctgctc cagcgtttca cgcagatcgg acgtcgcctg gtcgatattg tgctgcatct
    31681 cttcgtgata agcagccagc gacattgcca tcgagttgat accgtttttc agcatatcca
    31741 gctcgccgag cataaatcct tccacccggc tgtcgagttg cccgcgacgg atgcggtcga
    31801 cggtattcac catgttgcga atcggaccgg ttacatcgcg cattaagcgc cagccaaaaa
    31861 taagcgcaat accgatacaa aacagcatca tcacgctgga aataaagatc tctttatatt
    31921 gctgcaagcg aaccgattta agatccagct caagcgcaat atatcccaac atattttgac
    31981 tatttttggc atcgctactg ggcgattcgt cgggggagta actctcagaa ataatcggcg
    32041 tgcggaggat cataatatcg ccgtcacgag tgacagtgag ctggcgagga aacggcacgt
    32101 tgctgccgag ctgcattgat gagggatcaa gatgaaaatt ggaggtgaca aagagtcggt
    32161 tattttcatc ataaaccgaa atcgcgcgaa caatatcgga atggcgacga tgcagtacgc
    32221 ttattaactg accgatagat tcgcgatttt gcaggctcat gccatattca gtagaaactg
    32281 caagcggctc aataatgctg gcaccggcat cttccagttg acgctgcaag tcgttatagc
    32341 gatgcacgac gaaaaagata ctcagcaata aaccaataag gacggtcggt gccaggatca
    32401 gaatcatcat gcgtgcgcgc aggctgtagt tggtcatgga gttccgttat gggacaatta
    32461 aggtcacact gttaaattga gaaagtctcg ccaatggcgc aattctactc tgcaaaacga
    32521 cgcacgacga cgcgtcagat cataaccgtt tcagtcaacg acctcgactc ttttggtcag
    32581 ggcgtggcgc gacataacgg caaagcgtta tttattcctg gattactgcc acaggaaaac
    32641 gcggaagtta ctgttactga agataaaaaa cagtacgccc gcgctaaagt cgtgcgccgg
    32701 ttaagcgata gcccggaacg cgaaacgcca cgctgccctc attttggcgt atgcggtggc
    32761 tgtcagcaac aacacgccag cgtggattta cagcagcgaa gcaaaagtgc ggcactcgcc
    32821 cgattaatga aacacgaagt ctctgaagtg atcgccgatg ttccctgggg ctatcgccgt
    32881 cgcgcgcgtt taagtttgaa ctacttaccg aaaacacagc aacttcagat ggggtttcgc
    32941 aaagcgggct ccagtgacat tgtcgacgtt aaacaatgcc ccattttagc gccccaactt
    33001 gaagcattgc tgcccaaagt cagggcatgt ctgggcagct tacaagctat gcgccatctt
    33061 ggtcatgttg aactggtaca ggcaaccagc ggcacgctga tgattttgcg ccataccgca
    33121 ccgctaagtt cggcagatcg cgaaaaactg gaacgctttt cgcattctga aggcctggat
    33181 ctgtatctcg cccccgatag tgagatactc gaaaccgtct ctggtgagat gccctggtat
    33241 gactcaaacg ggttgcgctt aacttttagc ccgcgcgatt ttattcaggt caatgcgggt
    33301 gtgaaccaaa aaatggtagc gcgtgcgttg gaatggctgg atgtgcaacc tgaagatcgc
    33361 gtactggatc tgttctgcgg tatgggcaac tttacactgc cattggcgac acaagctgcc
    33421 agtgtggtcg gtgtagaagg tgttccggcg ctggtggaaa aaggccagca gaatgcgcgt
    33481 cttaatggct tacagaatgt gacgttttat cacgaaaatc ttgaagaaga tgtcacaaag
    33541 cagccgtggg cgaaaaacgg cttcgataaa gtgttgctgg acccggcgcg agcaggtgcc
    33601 gcaggtgtta tgcagcaaat tataaaactg gaacctattc gtatagttta tgtatcctgt
    33661 aaccctgcaa cgctggctcg ggatagcgaa gcgttattaa aagcaggata taccattgcg
    33721 cgactggcga tgctggatat gttcccacac acgggacatc tggaatcgat ggtacttttc
    33781 tcgcgcgtta aatagttgcg atttgccgat ttcggcaggt ctggtcccta aaggagagga
    33841 cgatggttgc ggtaagaagt gcacatatca ataaggctgg tgaatttgat ccggaaaaat
    33901 ggatcgcaag tctgggtatt accagccaga agtcgtgtga gtgcttagcc gaaacctggg
    33961 cgtattgtct gcaacagacg caggggcatc cggatgccag tctgttattg tggcgtggtg
    34021 ttgagatggt ggagatcctc tcgacattaa gtatggacat tgacacgctg cgggcggcgc
    34081 tgcttttccc tctggcggat gccaacgtag tcagcgaaga tgtgctgcgt gagagcgtcg
    34141 gtaagtcggt cgttaacctt attcacggcg tgcgtgatat ggcggcgatc cgccagctga
    34201 aagcgacgca cactgattct gtttcctccg aacaggtcga taacgttcgc cggatgttat
    34261 tggcgatggt cgatgatttt cgctgcgtag tcatcaaact ggcggagcgt attgctcatc
    34321 tgcgcgaagt aaaagatgcg ccggaagatg aacgtgtact ggcggcaaaa gagtgtacca
    34381 acatctacgc accgctggct aaccgtctcg gaatcggaca actgaaatgg gaactggaag
    34441 attactgctt ccgttacctc catccaaccg aatacaaacg aattgccaaa ctgctgcatg
    34501 aacggcgtct cgaccgcgaa cactacatcg aagagttcgt tggtcatctg cgcgctgaga
    34561 tgaaagctga aggcgttaaa gcggaagtgt atggtcgtcc gaaacacatc tacagcatct
    34621 ggcgtaaaat gcagaaaaag aacctcgcct ttgatgagct gtttgatgtg cgtgcggtac
    34681 gtattgtcgc cgagcgttta caggattgct atgccgcact ggggatagtg cacactcact
    34741 atcgccacct gccggatgag tttgacgatt acgtcgctaa cccgaaacca aacggttatc
    34801 agtctattca taccgtggtt ctggggccgg gtggaaaaac cgttgagatc caaatccgca
    34861 ccaaacagat gcatgaagat gcagagttgg gtgttgctgc gcactggaaa tataaagagg
    34921 gcgcggctgc tggcggcgca cgttcgggac atgaagaccg gattgcctgg ctgcgtaaac
    34981 tgattgcgtg gcaggaagag atggctgatt ccggcgaaat gctcgacgaa gtacgtagtc
    35041 aggtctttga cgaccgggtg tacgtcttta cgccgaaagg tgatgtcgtt gatttgcctg
    35101 cgggatcaac gccgctggac ttcgcttacc acatccacag tgatgtcgga caccgctgca
    35161 tcggggcaaa aattggcggg cgcattgtgc cgttcaccta ccagctgcag atgggcgacc
    35221 agattgaaat tatcacccag aaacagccga accccagccg tgactggtta aacccaaacc
    35281 tcggttacgt cacaaccagc cgtgggcgtt cgaaaattca cgcctggttc cgtaaacagg
    35341 accgtgacaa aaacattctg gctgggcggc aaatccttga cgacgagctg gaacatctgg
    35401 ggatcagcct gaaagaagca gaaaaacatc tgctgccgcg ttacaacttc aatgatgtcg
    35461 acgagttgct ggcggcgatt ggtggcgggg atatccgtct caatcagatg gtgaacttcc
    35521 tgcaatcgca atttaataag ccgagtgccg aagagcagga cgccgccgcg ctgaagcaac
    35581 ttcagcaaaa aagctacacg ccgcaaaacc gcagtaaaga taacggtcgc gtggtagtcg
    35641 aaggtgttgg caacctgatg caccacatcg cgcgctgctg ccagccgatt cctggagatg
    35701 agattgtcgg cttcattacc caggggcgcg gtatttcagt acaccgcgcc gattgcgaac
    35761 aactggcgga actgcgctcc catgcgccag aacgcattgt tgacgcggta tggggtgaga
    35821 gctactccgc cggatattcg ctggtggtcc gcgtggtagc taatgatcgt agtgggttgt
    35881 tacgtgatat cacgaccatt ctcgccaacg agaaggtgaa cgtgcttggc gttgccagcc
    35941 gtagcgacac caaacagcaa ctggcgacca tcgacatgac cattgagatt tacaacctgc
    36001 aagtgctggg gcgcgtgctg ggtaaactca accaggtgcc ggatgttatc gacgcgcgtc
    36061 ggttgcacgg gagttaggcc gaaatttgct cgtatctaca atgtagattg atatatactg
    36121 tatctacata tgatagcggt ttgaggaaag ggttatgatc cacagtagcg taaagcgttg
    36181 gggaaattca ccggcggtgc ggatcccggc tacgttaatg caggcgctca atctgaatat
    36241 tgatgatgaa gtgaagattg acctggtgga tggcaaatta attattgagc cagtgcgtaa
    36301 agagcccgta tttacgcttg ctgaactggt caacgacatc acgccggaaa acctccacga
    36361 gaatatcgac tggggagagc cgaaagataa ggaagtctgg taatggtaag ccgatacgta
    36421 cccgatatgg gcgatctgat ttgggttgat tttgacccga caaaaggtag cgagcaagct
    36481 ggacatcgtc cagctgttgt cctgagtcct ttcatgtaca acaacaaaac aggtatgtgt
    36541 ctgtgtgttc cttgtacaac gcaatcaaaa ggatatccgt tcgaagttgt tttatccggt
    36601 caggaacgtg atggcgtagc gttagctgat caggtaaaaa gtatcgcctg gcgggcaaga
    36661 ggagcaacga agaaaggaac agttgcccca gaggaattac aactcattaa agccaaaatt
    36721 aacgtactga ttgggtagtg ttactaactc acttctattc tggtcacagg tttccacctg
    36781 acagacccgc aattttcagg acaattcaat gaatcaaatc gaccgtttgc tcactattat
    36841 gcagcgcctg cgcgatccgg aaaacggctg cccgtgggat aaagagcaga catttgccac
    36901 cattgcgcct tacacccttg aagaaaccta cgaagtgctg gacgccatcg cccgtgaaga
    36961 ttttgacgat cttcgcggtg aactgggcga tctgctattc caggtggtgt tttacgcgca
    37021 aatggctcag gaagaagggc gctttgactt taatgatatt tgcgctgcta ttagcgataa
    37081 attagagcgt cgccatccgc atgtttttgc tgatagttct gccgaaaaca gtagtgaagt
    37141 gcttgcccgt tgggagcaaa tcaaaaccga agagcgcgcg cagaaagcgc agcattcggc
    37201 gctggacgat attcctcgta gtttaccggc tttaatgcgt gcgcaaaaaa tccagaaacg
    37261 ttgcgccaac gttggcttcg attggacgac gcttggtccg gtagtcgata aagtctacga
    37321 agagatcgac gaggtgatgt acgaagcgcg gcaggctgtt gtcgaccagg ctaaactgga
    37381 ggaggaaatg ggggacctgc tgtttgccac ggttaatctg gctcgccatt tagggacgaa
    37441 agcagaaatc gcattgcaaa aagcgaacga aaaattcgag cgtcgttttc gcgaagtgga
    37501 gcgtattgtt gccgcgcgtg gactggaaat gacaggtgtt gacctcgaaa caatggaaga
    37561 agtctggcaa caggtaaaac ggcaggaaat tgatctctaa gggaattacg cggtcaagcg
    37621 ccatttgtgt cattttttaa atgacaagcg cttgatttgc gtcaaaaaca tttaccccaa
    37681 aggggctatt ttctcactcc tgatttcaat agtgcgctgg cgaagaggag ggataatgaa
    37741 agtttgtggc acaggtcatg ttcgggtata ctgctttccc gtcttggtta ttccatcgtc
    37801 ttttcaacct aacttctcag gttcagcatg acaacgaact atatttttgt gaccggcggg
    37861 gtcgtatcct ctctgggtaa aggcattgcc gcagcctccc tcgcagccat tcttgaagcc
    37921 cgtggcctca atgtgaccat catgaaactg gatccgtaca tcaacgtcga tccaggtact
    37981 atgagcccaa tccaacacgg ggaagtgttc gttactgaag acggcgctga aaccgacctg
    38041 gacctggggc actacgagcg tttcattcgt accaaaatga gccgccgcaa caacttcacc
    38101 acgggtcgta tctactctga cgttctgcgt aaagaacgcc gcggtgacta cctcggcgca
    38161 accgtgcagg ttattccgca catcactaac gcaatcaaag agcgcgtgct ggaaggtggc
    38221 gaaggtcatg acgtagtact ggtagaaatc ggcggtacag taggtgatat cgaatccttg
    38281 ccgttcctcg aagcgattcg ccagatggct gttgaaattg gccgtgagca cactctgttt
    38341 atgcacctga cgctggtgcc gtacatggca gcgtctggtg aagtcaaaac caaaccgact
    38401 cagcactctg taaaagagct gctctccatc ggtatccagc ctgacatcct gatttgtcgt
    38461 tcagatcgcg ctgttccggc gaacgaacgt gcgaagattg cattgttctg taatgttccg
    38521 gaaaaagcgg ttatttctct gaaagacgtc gattccatct ataaaattcc gggcctgttg
    38581 aaatctcagg ggctggacga ttatatttgt aaacgattca gcttaaactg cccggaagcg
    38641 aatctgtccg aatgggaaca ggttatcttc gaagaagcga acccggtaag tgaagtcacc
    38701 atcggtatgg tcggcaagta cattgaactg ccggatgctt ataaatcagt gatcgaagca
    38761 ctgaaacacg gtgggctgaa gaatcgtgtc agcgtcaaca tcaaactgat cgattcacaa
    38821 gatgttgaaa cgcgcggcgt tgaaatcctt aaaggtctgg acgcaatcct cgtacctggc
    38881 ggtttcggct atcgtggcgt agaaggcatg attacgaccg cgcgttttgc gcgtgagaac
    38941 aatattcctt atctgggcat ttgcctgggt atgcaggtgg cgttaattga ttacgctcgc
    39001 catgttgcca acatggagaa cgccaactct acggaatttg tgccagactg taagtacccg
    39061 gttgtggcgc tgattaccga gtggcgcgat gaaaacggca acgttgaagt tcgtagcgag
    39121 aagagcgatc tcggcggtac catgcgtctc ggcgcacagc agtgccagtt ggttgacgat
    39181 agcctggttc gccagctgta caatgcgccg acaattgttg agcgtcatcg tcaccgttac
    39241 gaagtcaaca acatgctgtt gaaacagatt gaagatgcag gtctgcgcgt tgcgggccgt
    39301 tccggggatg atcagttggt cgagatcatc gaagttccga atcacccgtg gttcgtggct
    39361 tgccagttcc atccggagtt tacttctact ccacgtgatg gtcacccgct gtttgcaggc
    39421 tttgtgaaag ccgccagcga gttccagaaa cgtcaggcga agtaagtaaa aaagttagag
    39481 cggcaacgcg taccctgggt acgcgttgtt tgtctggagt ttcagtttaa ctagtgactt
    39541 gaggaaaacc taatgtccaa aatcgtaaaa atcatcggtc gtgaaatcat cgactcccgt
    39601 ggtaacccga ctgttgaagc cgaagtacat ctggagggtg gtttcgtcgg tatggcagct
    39661 gctccgtcag gtgcttctac tggttcccgt gaagctctgg aactgcgcga tggcgacaaa
    39721 tcccgtttcc tgggtaaagg cgtaaccaaa gctgttgctg cggtaaacgg cccgatcgct
    39781 caggcgctga ttggcaaaga tgctaaagat caggctggca ttgacaagat catgatcgac
    39841 ctggacggca ccgaaaacaa atccaaattc ggcgcgaacg caatcctggc tgtatctctg
    39901 gctaacgcca aagctgctgc agctgctaaa ggtatgccgc tgtacgagca catcgctgaa
    39961 ctgaacggta ctccgggcaa atactctatg ccggttccga tgatgaacat catcaacggt
    40021 ggtgagcacg ctgacaacaa cgttgatatc caggaattca tgattcagcc ggttggcgcg
    40081 aaaactgtga aagaagccat ccgcatgggt tctgaagttt tccatcacct ggcaaaagtt
    40141 ctgaaagcga aaggcatgaa cactgcagtt ggtgacgaag gtggctatgc gccgaacctg
    40201 ggttccaacg ctgaagctct ggctgttatc gctgaagctg ttaaagctgc tggttatgaa
    40261 ctgggcaaag acatcactct ggcgatggac tgcgcagctt ctgaattcta caaagacggt
    40321 aaatacgttc tggctggcga aggcaacaaa gcgttcacct ctgaagaatt cactcacttc
    40381 ctggaagaac tgaccaaaca gtacccgatc gtttctatcg aagacggtct ggacgaatct
    40441 gactgggacg gtttcgcata ccagaccaaa gttctgggcg acaaaatcca gctggttggt
    40501 gacgacctgt tcgtaaccaa caccaagatc ctgaaagaag gtatcgaaaa aggtatcgct
    40561 aactccatcc tgatcaaatt caaccagatc ggttctctga ccgaaactct ggctgcaatc
    40621 aagatggcga aagatgctgg ctacactgca gttatctctc accgttctgg cgaaactgaa
    40681 gacgctacca tcgctgacct ggctgttggt actgctgcag gccagatcaa aactggttct
    40741 atgagccgtt ctgaccgtgt tgctaaatac aaccagctga ttcgtatcga agaagctctg
    40801 ggcgaaaaag caccgtacaa cggtcgtaaa gagatcaaag gccaggcata agactgactt
    40861 aacgtcttaa taaaaaaccc gcttcttgaa gcgggttttt ttatcttcac attttgagtt
    40921 tagtaagcag agcgataaca ttaataaatg ttattcccac caggataagt atccgaacaa
    40981 tttttctgct attccttaca ttgctgacaa aatcattatg agaaatattg gatgaatatt
    41041 ttcgttgatg gactttataa tcccaaagaa aatcatttgc ctcaggtatt gggttaatca
    41101 gactgtagat gcaaaagttc acaaacgtat ctaaagcaag cagtgatgtt atcagttgaa
    41161 ataattcatc gccctggaag gctttattaa gccaaatcat tccagcagca ccgaataagc
    41221 caaatacaaa tttacttaat cgtggatgat tcgctaaaat cttactcata tttccttacc
    41281 ttccctgtaa tctgttttta agtcttacca tcttcctgac gcgccgccac cgccggatga
    41341 accgccacca ccgctgaaat tgtcattgtt gaaagaggat gaagaggaag atgacgatga
    41401 tgaagaatgt cgggaggccg agttgcttct ttcgtaacgt gacggtcggt tggcgctacg
    41461 cattgaatca cgcacctttc tgccgaaagg cgtgaaagcg atagctacga ccaggaatgg
    41521 agtggcgaaa cataataatg tggcaagaac tccccagctc ccgctatatc cagcgatggg
    41581 aagtacaaag gccagtatta tggcagcaaa gcaaatcact cccagcgttt tgacatatcc
    41641 tctggcagaa ataaacgtca gtactatcgc ccagactaac agagcccacc aaccgctaaa
    41701 gggtaaagga tgatcgggcg atgtattatt gactaaatca ttttctgata atcgggtttc
    41761 aatatcacca ataccttgtt gcaagccgac agcaagatcg ccctttttaa acgcaggaat
    41821 aatactgttg cgtataattt gcccggactg cgcatccgtc agaataccct caagtccgta
    41881 gccaatttca atatgtactg tatgatcttg ccaggcaact accagtaaaa taccgtcatc
    41941 aagattctta tgaccgggct gccaacgctc gaatactcgt gttgcatatt gctcgatggt
    42001 ttcatcgcct gttgtttcta ctactaacac gatcagttgt gcgtggcttt tttgcgtcag
    42061 ggttttaatc tgactggtca gcgtacttac ttcctccctg gttaatgtcc ctgttaaatc
    42121 atttatatac ttagcgaatt caggtactgg aacttgcact gcaaacgcag atgaacagat
    42181 cagaacaaga agtaagatta aatttttcat ataattaact cgcctaatga gcactagcat
    42241 tctggctaaa atctattgtt ggtgctttac tcacagcggc gacatcatcc ggcaaataat
    42301 ttttcttcgg tgtgtaatcc atgacctttg cggttaatac agcggggaat ttgcggatag
    42361 taacattata ttgttcaatg gctttaatat atcttcctcg cgcaacggca attcgatttt
    42421 cacttccttc gagctgtacc attaagtttt gatagagctc ttgagccttt aactcagggt
    42481 aacgctcact aattatcgtt aactgaccga gagtgcgaat cacctgcgct tgagcctgtt
    42541 gccaggcttg taatttttgt tcatttcccg gagtttgctg aagatcgctg ctggcgcgat
    42601 tagcctggct acgagccaat gttacggctt ccaaaacgtc tttttcatgg ttggaataac
    42661 ctttaatact ggcgacaaga ttaggaataa gatcggcgcg acgttgatat tgatttaata
    42721 cctcagacca ggaggcgtta acctgctcat cataggtttg aatatcgtta tatccacagc
    42781 ctgataaatt gaaaataaat ataattacga tgaatgtcct gagcatgttt aaatcctttt
    42841 tcattaattc cttaaaacat aatacgtcgc atcattttat tctttatgat ctaatgcact
    42901 ttttgcctta aacctgcctg taacagaatg ttaataagac atgattgttg cggcaggatc
    42961 tgcaataatt aacaattatc cacttcacag agaatgctat gcagtacccg attaacgaga
    43021 tgttccagac cctgcaaggt gagggttact ttaccggcgt tcccgccatt tttattcgtt
    43081 tacagggatg cccggttggc tgtgcctggt gcgacaccaa acacacctgg gaaaagcttg
    43141 aggatcggga agtctccctt ttcagcattc tggcgaagac caaagagagt gataagtggg
    43201 ggtcggcgag cagtgaagat ttgctggctg tcattggtcg ccagggatac accgcgcggc
    43261 atgtggtgat tacgggtggt gagccttgca ttcatgattt gctaccactg actgatctgc
    43321 tcgaaaagaa cggttttagc tgccagatcg aaaccagtgg tactcatgag gtacgctgca
    43381 caccgaatac ctgggttacc gtatcgccaa agctgaacat gcgcggcggc tatgacgtgt
    43441 tgtcacaggc actggagcga gccaacgaaa tcaagcatcc agtggggcgc gtacgcgata
    43501 ttgaagcact ggatgaacta ttggcaacgc tgaccgatga taaaccgcga gtcattgcac
    43561 tgcagccgat tagccaaaag gatgatgcca cacgtttgtg cattgaaacc tgcattgcgc
    43621 gtaattggcg tttgtcgatg caaacacata aatatctaaa tattgcctga ttaaacattt
    43681 ataagcgtta taaatgggtg gaacctgtaa agacttctac tcatttatat tgtttgtcgc
    43741 ctctgaaaac tcctccattt tacccatcca gggctaatca ttagcattct ctacaaattc
    43801 tgtggcatta atttttcgct ggagtgaaaa ttattgcggt aaagtttggt agatt
//
LOCUS       DAPOAV010000032        42818 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.032, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000032 DAPOAV010000000
VERSION     DAPOAV010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 42818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42818
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.032"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(235..1098)
                     /locus_tag="RN951_002007"
     CDS             complement(235..1098)
                     /locus_tag="RN951_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjW family glycine radical enzyme activase"
                     /protein_id="HDX2527008.1"
                     /translation="MNSRCALVSKIIPFSCVDGPGSRLALFLQGCNLRCKNCHNPWTM
                     GRCNDCGECVPQCPHQALQIVDGKVLWNAVVCEQCDTCLKMCPQHATPMAQSMSVDEM
                     LSHVRKAVLFIEGITVSGGEATTQLPFVVALFTAIKNDPQLRHLTCLVDSNGMLSETG
                     WEKLLPVCDGAMLDLKAWGSECHQQLTGRDNQQIKRSICLLAERGKLAELRLLVIPDQ
                     VDYLHHIDELATFIKRLGDVPVRLNAFHAHGVYGEAQSWASATPEDVEPLADALKVRG
                     VSRLIFPALYL"
     gene            complement(1070..2620)
                     /locus_tag="RN951_002008"
     CDS             complement(1070..2620)
                     /locus_tag="RN951_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjI family glycine radical enzyme"
                     /protein_id="HDX2527009.1"
                     /translation="MPTSHENALQQRCQQIVTSPVLSPEQKRHFLALEAENNLPYPQL
                     PAEARRALDEGVICDMFEGHAPYKPRYVLPDYARFLANGSEWLELEGAKDLDDALSLL
                     TILYHHVPSVTWMPVYLGQLDALLQPYVRILTQDEIDVRIKRFWRYLDRTLPDAFMHA
                     NIGPSDSPITRAILRADAELKQVSPNLTFIYDPEITPDDLLLEVAKNICECSKPHIAN
                     GPVHDKIFTKGGYGIVSCYNSLPLAGGGSTLVRLNLKAIAERSESLDDFFTRTLPHYC
                     QQQIAIIDARCEFLYQQSHFFENSFLVKEGLINPERFVPMFGMYGLAEAVNLLCEKEG
                     IAARYGKEAAANEVGYRISAQLAEFVANTPVKYGWQKRAMLHAQSGISSDIGTTPGAR
                     LPYGDEPDPITHLQTVAPHHAYYYSGISDILTLDETIKRNPQALVQLCLGAFKAGMRE
                     FTANVSGNDLVRVTGYMVRLSDLEKYRAEGSRTNTTWLGEEAARNTRILERQPRVISH
                     EQQMRFSQ"
     gene            2879..3658
                     /gene="deoC"
                     /locus_tag="RN951_002009"
     CDS             2879..3658
                     /gene="deoC"
                     /locus_tag="RN951_002009"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005097947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDX2527010.1"
                     /translation="MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTA
                     AICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVD
                     VVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIK
                     AGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAI
                     ADELFGADWADARHYRFGASSLLASLLKALGHGDGKSTSSY"
     gene            3825..5147
                     /gene="deoA"
                     /locus_tag="RN951_002010"
     CDS             3825..5147
                     /gene="deoA"
                     /locus_tag="RN951_002010"
                     /EC_number="2.4.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313368.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine phosphorylase"
                     /protein_id="HDX2527011.1"
                     /translation="MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAM
                     TIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMV
                     AACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSL
                     APADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMSTYELSE
                     ALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVT
                     MALCVEMLTSGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYL
                     PTAMLTKAVYADTEGFVSDMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQ
                     VDGQRPLAVIHAKDENSWQEAAKAVKAAIKLADKAPESTPTVYRRISE"
     gene            5199..6422
                     /gene="deoB"
                     /locus_tag="RN951_002011"
     CDS             5199..6422
                     /gene="deoB"
                     /locus_tag="RN951_002011"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDX2527012.1"
                     /translation="MKRAFIMVLDSFGIGATEDAERFGDVGADTLGHIAEACAKGEAD
                     NGRKGPLNLPNLTRLGLAKAHEGSTGFIPAGMDGNAEVIGAYAWAHEMSSGKDTPSGH
                     WEIAGVPVLFEWGYFSDHENSFPQELLDKLVERANLPGYLGNCHSSGTVILDQLGEEH
                     MKTGKPIFYTSADSVFQIACHEETFGLDKLYELCEIAREELTNGGYNIGRVIARPFIG
                     DKAGNFQRTGNRHDLAVEPPAPTVLQKLVDEKHGQVVSVGKIADIYANCGITKKVKAT
                     GLDALFDATIKEMKEAGDNTIVFTNFVDFDSSWGHRRDVAGYAAGLELFDRRLPELMS
                     LLRDDDILILTADHGCDPTWTGTDHTREHIPVLVYGPKVKPGSLGHRETFADIGQTLA
                     KYFGTSDMEYGKAMF"
     gene            6479..7198
                     /gene="deoD"
                     /locus_tag="RN951_002012"
     CDS             6479..7198
                     /gene="deoD"
                     /locus_tag="RN951_002012"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDX2527013.1"
                     /translation="MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVR
                     GMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLR
                     DVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLF
                     YSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAER
                     QTTFNDMIKIALESVLLGDKE"
     gene            7365..8696
                     /gene="yjjJ"
                     /locus_tag="RN951_002013"
     CDS             7365..8696
                     /gene="yjjJ"
                     /locus_tag="RN951_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HipA family toxin
                     YjjJ"
                     /protein_id="HDX2527014.1"
                     /translation="MSELTDLLLQGPRSAPELRQRLAISQATFSRLVAREDRVIRFGK
                     ARATRYALLRPYRGIERILVWRVDDAGKAHKFADIQLCWPQGSCLVTGGKGDEQWFDG
                     LPWYLTDLRPQGFLGRAWGRNLAGQLNLTEDIRLWQEEDVLYALTVFNGEYTGGWLVG
                     ERNYQRWITAPRPAAIPLDQKLTRYEQLAHDALAGEIVGSSAGGEQPKFTCYVQTPSG
                     NKHVLVKFTVPQQTAVSQRWGDLLIAESIAAQILCDGGIHAIESTVLVTSNRQVFLEA
                     ERFDCKGNDGRLPIVSLEAVQSEFISSPGSWPEAMRRLCEQQFVTHQSVAQTEVIWAF
                     GRLIANSDMHAGNLSFYLSEPPFALTPVYDMLPMAYAPNSAGMLRDAAIEVKFDLNVS
                     KSAWLTAIPLAQQFWQTVAGDPRISEAFRHIAQEMPEKIRQIEGKVARMGG"
     gene            complement(8697..9713)
                     /gene="lplA"
                     /locus_tag="RN951_002014"
     CDS             complement(8697..9713)
                     /gene="lplA"
                     /locus_tag="RN951_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase LplA"
                     /protein_id="HDX2527015.1"
                     /translation="MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTV
                     VIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTIST
                     SIVLNALNALGVSAEASGRNDLVVKTAEGDRKVSGSAYRETKDRGFHHGTLLLNADLS
                     RLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAISETFFAHYGERTEA
                     EIISPDKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGHI
                     TRTQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECEALLVDFPEQEKELRELSAWIA
                     GAVR"
     gene            complement(9741..10385)
                     /locus_tag="RN951_002015"
     CDS             complement(9741..10385)
                     /locus_tag="RN951_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtjB family periplasmic protein"
                     /protein_id="HDX2527016.1"
                     /translation="MARTKLKFRLHRAVIVLFCLALLVALMQGASWFSQNHQRQRNPQ
                     LEELARTLARQVTLNVAPLMRTDSPDEKRIQAILDQLTDESRILDAGVYDEQGDLIAR
                     SGESVEVRDRLALDGKKAGGYFNQQIVEPIAGKNGPLGYLRLTLDTHTLATEAQQVDN
                     TTNILRLMLLLSLAIGVVLTRTLLQGKRTRWQQSPFLLTASKPVPEEEESEKKE"
     gene            10491..11459
                     /gene="serB"
                     /locus_tag="RN951_002016"
     CDS             10491..11459
                     /gene="serB"
                     /locus_tag="RN951_002016"
                     /EC_number="3.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase"
                     /protein_id="HDX2527017.1"
                     /translation="MPNITWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYG
                     RGLDKQRLTQYQSKLGAAMVIVAAWCVEDYQVIRLAGSLTARATRLAHEAQLDVAPLG
                     KIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGTGEMVAEVTERAMRGELDFTASLRS
                     RVATLKGADANILQQVRENLPLMPGLTQLVLKLETLGWKVAIASGGFTFFAEYLRDKL
                     RLTAVVANELEIMDGKFTGNVIGDIVDAQYKAKTLTRLAQEYEIPLAQTVAIGDGAND
                     LPMIKAAGLGIAYHAKPKVNEKAEVTIRHADLMGVFCILSGSLNQK"
     gene            11508..12890
                     /gene="radA"
                     /locus_tag="RN951_002017"
     CDS             11508..12890
                     /gene="radA"
                     /locus_tag="RN951_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001399683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HDX2527018.1"
                     /translation="MAKAPKRAFVCNECGADYPRWQGQCSACHAWNTITEVRLAASPT
                     VARNERLSGYAGSAGVAKVQKLSDISLEELPRFSTGFKEFDRVLGGGVVPGSAILIGG
                     NPGAGKSTLLLQTLCKLAQQMKTLYVTGEESLQQVAMRAHRLGLPTDNLNMLSETSIE
                     QICLIAEEEQPKLMVIDSIQVMHMADVQSSPGSVAQVRETAAYLTRFAKTRGVAIVMV
                     GHVTKDGSLAGPKVLEHCIDCSVLLDGDADSRFRTLRSHKNRFGAVNELGVFAMTEQG
                     LREVSNPSAIFLSRGDEVTSGSSVMVVWEGTRPLLVEIQALVDHSMMANPRRVAVGLE
                     QNRLAILLAVLHRHGGLQMADQDVFVNVVGGVKVTETSADLALLLAMVSSLRDRPLPQ
                     DLVVFGEVGLAGEIRPVPSGQERISEAAKHGFRRAIVPAANVPKKAPEGMQIFGVKKL
                     SDALSVFDDL"
     gene            12911..14143
                     /gene="nadR"
                     /locus_tag="RN951_002018"
     CDS             12911..14143
                     /gene="nadR"
                     /locus_tag="RN951_002018"
                     /EC_number="2.7.1.22"
                     /EC_number="2.7.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418807.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional transcriptional
                     regulator/nicotinamide-nucleotide
                     adenylyltransferase/ribosylnicotinamide kinase NadR"
                     /protein_id="HDX2527019.1"
                     /translation="MSSFDYLKTAIKQQGCTLQQVADASGMTKGYLSQLLNAKIKSPS
                     AQKLEALHRFLGLEFPRQKKTIGVVFGKFYPLHTGHIYLIQRACSQVDELHIIMGFDD
                     TRDRALFEDSAMSQQPTVPDRLRWLLQTFKYQKNIRIHAFNEEGMEPYPHGWDVWSNG
                     IKKFMAEKGIQPDLIYTSEEADAPQYMEHLGIDTVLVDPKRTFMSISGAQIRENPFRY
                     WEYIPTEVKPFFVRTVAILGGESSGKSTLVNKLANIFNTTSAWEYGRDYVFSHLGGDE
                     IALQYSDYDKIALGHAQYIDFAVKYANKVAFIDTDFVTTQAFCKKYEGREHPFVQALI
                     DEYRFDLVILLENNTPWVADGLRSLGSSVDRKEFQNLLVEMLEENNIEFVRVEEDDYD
                     SRFLRCVELVREMMGEQR"
     gene            complement(14450..16117)
                     /gene="ettA"
                     /locus_tag="RN951_002019"
     CDS             complement(14450..16117)
                     /gene="ettA"
                     /locus_tag="RN951_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017145039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-dependent translational throttle protein
                     EttA"
                     /protein_id="HDX2527020.1"
                     /translation="MAQFVYTMHRVGKVVPPKRHILKNISLSFFPGAKIGVLGLNGAG
                     KSTLLRIMAGIDKDIEGEARPQPDIKIGYLPQEPQLNPEHTVRESIEEAVSEVVNALK
                     RLDEVYALYADPDADFDKLAAEQGRLEEIIQAHDGHNLNVQLERAADALRLPDWDAKI
                     ANLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLERFLHDFEGTVVAITHD
                     RYFLDNVAGWILELDRGEGIPWEGNYSSWLEQKDQRLAQEASQEAARRKSIEKELEWV
                     RQGTKGRQSKGKARLARFEELNSTEYQKRNETNELFIPPGPRLGDKVLEVSNLRKSYG
                     DRLLIDDLSFSIPKGAIVGIIGPNGAGKSTLFRMISGQEQPDSGTITLGETVKLASVD
                     QFRDSMDNSKTVWEEVSGGLDIMKIGNTEMPSRAYVGRFNFKGVDQGKRVGELSGGER
                     GRLHLAKLLQVGGNMLLLDEPTNDLDIETLRALENALLEFPGCAMVISHDRWFLDRIA
                     THILDYQDEGKVEFFEGNFTEYEEYKKRTLGADALEPKRIKYKRIAK"
     gene            16328..18265
                     /gene="sltY"
                     /locus_tag="RN951_002020"
     CDS             16328..18265
                     /gene="sltY"
                     /locus_tag="RN951_002020"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase"
                     /protein_id="HDX2527021.1"
                     /translation="MEKAKQVTWRLLAAGVCLLTVSSVARADSLDEQRSRYAQIKQAW
                     DNRQMDVVEQMMPGLKDYPLYPYLEYRQITDDLMNQPAVTVTNFVRANPTLPPARTLQ
                     SRFVNELARREDWRGLLAFSPEKPGTTEAQCNYYYAKWNTGQSEEAWQGAKELWLTGK
                     SQPNACDKLFSVWRASGKQDPLAYLERIRLAMKAGNTGLVTVLAGQMPADYQTIASAI
                     ISLANNPNTVLTFARTTGATDFTRQMAAVAFASVARQDAENARLMIPSLAQAQQLNED
                     QIQELRDIVAWRLMGNDVTDEQAKWRDDAIMRSQSTSLIERRVRMALGTGDRRGLNTW
                     LARLPMEAKEKDEWRYWQADLLLERGREAEAKEILHQLMQQRGFYPMVAAQRIGEEYE
                     LKIDKAPQNVDSALTQGSEMARVRELMYWNLDNTARSEWANLVKSKSKTEQAQLARYA
                     FNNQWWDLSVQATIAGKLWDHLEERFPLAYNDLFKRYTSGKEIPQSYAMAIARQESAW
                     NPKVKSPVGASGLMQIMPGTATHTVKMFSIPGYSSPGQLLDPETNINIGTSYLQYVYQ
                     QFGNNRIFSSAAYNAGPGRVRTWLGNSAGRIDAVAFVESIPFSETRGYVKNVLAYDAY
                     YRYFMGDKPTLMSATEWGRRY"
     gene            18355..18681
                     /gene="trpR"
                     /locus_tag="RN951_002021"
     CDS             18355..18681
                     /gene="trpR"
                     /locus_tag="RN951_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon repressor"
                     /protein_id="HDX2527022.1"
                     /translation="MAQQSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLT
                     PDEREALGTRVRIVEELLRGEMSQRELKNELGAGIATITRGSNSLKAAPVELRQWLEE
                     VLLKSD"
     gene            complement(18766..19287)
                     /gene="yjjX"
                     /locus_tag="RN951_002022"
     CDS             complement(18766..19287)
                     /gene="yjjX"
                     /locus_tag="RN951_002022"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001649724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/xanthosine triphosphatase"
                     /protein_id="HDX2527023.1"
                     /translation="MHQVVCATTNPAKIQAILQAFHEIFGEGSCHIASVAVESGVPEQ
                     PFGSEETRAGARNRVANARRLLPEADFWVAIEAGIDGDSTFSWVVIENASQRGEARSA
                     TLPLPAVILEKVREGEALGPVMSRYTGIDEIGRKEGAIGVFTAGKLTRASVYHQAVIL
                     ALSPFHNAVYQAL"
     gene            19339..19986
                     /gene="gpmB"
                     /locus_tag="RN951_002023"
     CDS             19339..19986
                     /gene="gpmB"
                     /locus_tag="RN951_002023"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase GpmB"
                     /protein_id="HDX2527024.1"
                     /translation="MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAK
                     ELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRLRELNMGVLEKRHIDSLTEEEEN
                     WRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVST
                     ILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR"
     gene            complement(19983..20852)
                     /gene="robA"
                     /locus_tag="RN951_002024"
     CDS             complement(19983..20852)
                     /gene="robA"
                     /locus_tag="RN951_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     RobA"
                     /protein_id="HDX2527025.1"
                     /translation="MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKD
                     VTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQTFTRAFKKQFAQTPAL
                     YRRSPEWSAFGIRPPLRLGEFTMPEHKFVTLEDTPLIGVTQSYSCSLEQISDFRHEMR
                     YQFWHDFLGNAPTIPPVLYGLNETRPSQDKDDEQEVFYTTALAQDQADGYVLTGHPVM
                     LQGGEYVMFTYEGLGTGVQEFILTVYGTCMPMLNLTRRKGQDIERYYPAEDAKAGDRP
                     INLRCELLIPIRR"
     gene            21063..21536
                     /gene="creA"
                     /locus_tag="RN951_002025"
     CDS             21063..21536
                     /gene="creA"
                     /locus_tag="RN951_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CreA"
                     /protein_id="HDX2527026.1"
                     /translation="MKYKHLILSLSLIMLGPLAHAEEIGSVDTVFKMIGPDHKIVVEA
                     FDDPDVKNVTCYVSRAKTGGIKGGLGLAEDTSDAAISCQQVGPIELSDRIKNGKAQGE
                     VVFKKRTSLVFKSLQVVRFYDAKRNALAYLAYSDKVVEGSPKNAISAVPVMPWRQ"
     gene            21549..22238
                     /gene="creB"
                     /locus_tag="RN951_002026"
     CDS             21549..22238
                     /gene="creB"
                     /locus_tag="RN951_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CreB"
                     /protein_id="HDX2527027.1"
                     /translation="MQRETVWLVEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKAR
                     QQAPDVMILDVGLPDISGFELCRQLLALHPALPVLFLTARSEEVDRLLGLEIGADDYV
                     AKPFSPREVCARVRTLLRRVKKFSSPSPVIRIGHFELNEPAAQISWFDTPLTLTRYEF
                     LLLKTLLKSPGRVWSRQQLMDSVWEDAQDTYDRTVDTHIKTLRAKLRAINPDLSPINT
                     HRGMGYSLRGL"
     gene            22238..23662
                     /gene="creC"
                     /locus_tag="RN951_002027"
     CDS             22238..23662
                     /gene="creC"
                     /locus_tag="RN951_002027"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CreC"
                     /protein_id="HDX2527028.1"
                     /translation="MRIGMRLLLGYFLLVAVAAWFVLAIFVKEVKPGVRRATEGTLID
                     TATLLAELARPDLLSGDPTHGQLAQAFNQLQHRPFRANIGGINKVRNEYHVYMTDSQG
                     KVLFDSANKAVGQDYSRWNDVWLTLRGQYGARSTLQNPADPESSVMYVAAPIMDGSRL
                     IGVLSVGKPNAAMAPVIKRSERRILWASAILLGIALVIGAGMVWWINRSIARLTRYAD
                     SVTDNKPVPLPELGSSELRKLAQALESMRVKLEGKNYIEQYVYALTHELKSPLAAIRS
                     AAEILREGPPPEVVARFTDNILTQNARMQALVETLLRQARLENRQEVVLTVVDVAALF
                     RRVSEARTVQLAEKNITLHVMPTEVNVAAEPALLEQALGNLLDNAIDFTPESGRITLS
                     AEVDQEHVALKVLDTGSGIPDYALSRIFERFYSLPRANGQKSSGLGLAFVSEVARLFN
                     GEVTLRNVQEGGVLASLRLHRHFT"
     gene            23720..25072
                     /gene="creD"
                     /locus_tag="RN951_002028"
     CDS             23720..25072
                     /gene="creD"
                     /locus_tag="RN951_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein CreD"
                     /protein_id="HDX2527029.1"
                     /translation="MLKSPLFWKMTTLFGAVLLLLIPIMLIRQVIVERADYRSDVEDA
                     IRQSTSGPQKLVGPLIAIPVTELYTVQEEDKTVERKRSFIHFWLPESLMVDGNQNVEE
                     RKIGIYTGQVWHSDLTLKADFDVSRLSELDAPNITFGKPFIVISVGDARGIGVVKAPE
                     VNGTALTIEPGTGLEQGGQGVHIPLPEGDWRKQNLQLNMALNLSGTGDLSVVPAGRNS
                     EMTLTSNWPHPSFLGDFLPAKREVSESGFQAQWQSSWFANNLGERFASGNDTGWENFP
                     AFSVAVTTPADQYQLTDRATKYAILLIALTFMAFFVFETLTAQRLHPMQYLLVGLSLV
                     MFYLLLLALSEHTGFTGAWIIASLIGALMNGIYLQAVLKGWRNSMLFTLALLLLDGVM
                     WGLLNSADSALLLGTSVLVVALAGMMFVTRNIDWYAFSLPKMKANKEVTTDDELRIWK
                     "
     gene            complement(25131..25847)
                     /gene="arcA"
                     /locus_tag="RN951_002029"
     CDS             complement(25131..25847)
                     /gene="arcA"
                     /locus_tag="RN951_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003621071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator ArcA"
                     /protein_id="HDX2527030.1"
                     /translation="MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILS
                     EYDINLVIMDINLPGKNGLLLARELREQANVALMFLTGRDNEVDKILGLEIGADDYIT
                     KPFNPRELTIRARNLLSRTMNLGTVSEERRSVESYKFNGWELDINSRSLIGPDGEQYK
                     LPRSEFRAMLHFCENPGKIQSRAELLKKMTGRELKPHDRTVDVTIRRIRKHFESTPDT
                     PEIIATIHGEGYRFCGDLED"
     gene            25943..26083
                     /locus_tag="RN951_002030"
     CDS             25943..26083
                     /locus_tag="RN951_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527031.1"
                     /translation="MTKVRNCVLDALSINVNNIISLVVGTFPQDPTVSKTAVILTILT
                     AT"
     gene            26483..27169
                     /locus_tag="RN951_002031"
     CDS             26483..27169
                     /locus_tag="RN951_002031"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HDX2527032.1"
                     /translation="MRITIILVAPARAENIGAAARAMKTMGFSELRIVDSQAHLEPAT
                     RWVAHGSGDIIDNIKVFPTLVESLHDVDFTVATTARSRAKYHYYATPVELVPLLEEKS
                     SWMSHAALVFGREDSGLTNEELALADVLTGVPMVADYPSLNLGQAVMVYCYQLATLIQ
                     QPTKSDTTADQHQLQALRERVMALLTTLAVADDTKLVDWLQQRLGLLEQRDTAMLHRL
                     LHDIEKNITK"
     gene            27383..27448
                     /gene="thrL"
                     /locus_tag="RN951_002032"
     CDS             27383..27448
                     /gene="thrL"
                     /locus_tag="RN951_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thr operon leader peptide"
                     /protein_id="HDX2527033.1"
                     /translation="MKRISTTITTTITITTGNGAG"
     misc_feature    27384..27503
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00506"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Thr leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00506"
     gene            27529..29991
                     /gene="thrA"
                     /locus_tag="RN951_002033"
     CDS             27529..29991
                     /gene="thrA"
                     /locus_tag="RN951_002033"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase I"
                     /protein_id="HDX2527034.1"
                     /translation="MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKIT
                     NHLVAMIEKTISGQDALPNISDAERIFAELLTGLTAAQPGFPLAQLKTFVDQEFAQIK
                     HVLHGISLLGQCPDSINAALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHY
                     LESTVDIAESTRRIAASRIPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACL
                     RADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQF
                     QIPCLIKNTGNPQAPGTLIGASRDEDELPVKGISNLNNMAMFSVSGPGMKGMVGMAAR
                     VFAAMSRARISVVLITQSSSEYSISFCVPQSDCVRAERAMQEEFYLELKEGLLEPLAV
                     TERLAIISVVGDGMRTLRGISAKFFAALARANINIVAIAQGSSERSISVVVNNDDATT
                     GVRVTHQMLFNTDQVIEVFVIGVGGVGGALLEQLKRQQSWLKNKHIDLRVCGVANSKA
                     LLTNVHGLNLENWQEELAQAKEPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYAD
                     FLREGFHVVTPNKKANTSSMDYYHQLRYAAEKSRRKFLYDTNVGAGLPVIENLQNLLN
                     AGDELMKFSGILSGSLSFIFGKLDEGMSFSEATTLAREMGYTEPDPRDDLSGMDVARK
                     LLILARETGRSLELADIEIESVLPAEFNAEGDVATFMANLSQLDDLFAARVAKARDEG
                     KVLRYVGNIDEDGVCRVKIAEVDGNDPLFKVKNGENALAFYSHYYQPLPLVLRGYGAG
                     NDVTAAGVFADLLRTLSWKLGV"
     gene            29993..30925
                     /gene="thrB"
                     /locus_tag="RN951_002034"
     CDS             29993..30925
                     /gene="thrB"
                     /locus_tag="RN951_002034"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HDX2527035.1"
                     /translation="MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETF
                     SLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACS
                     VVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDI
                     ISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQ
                     PELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTA
                     QRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN"
     gene            30926..32212
                     /gene="thrC"
                     /locus_tag="RN951_002035"
     CDS             30926..32212
                     /gene="thrC"
                     /locus_tag="RN951_002035"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HDX2527036.1"
                     /translation="MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEID
                     EMLKLDFVTRSAKILSAFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGP
                     TLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRG
                     KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISR
                     LLAQICYYFEAVAQLPQEARNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVN
                     DTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDE
                     TTQQTMRELKELGYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVEAILGE
                     TLDLPKELAERADLPLLSHNLPADFAALRKLMMNHQ"
     gene            32426..32722
                     /locus_tag="RN951_002036"
     CDS             32426..32722
                     /locus_tag="RN951_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2502 domain-containing protein"
                     /protein_id="HDX2527037.1"
                     /translation="MKKMQSIVLALSLVLVAPMAAQAAEITLVPSVKLQIGDRDNRGY
                     YWDGGHWRDHGWWKQHYEWRGNRWHPHGPPPPPRHHKKAHHDHHGGHGPGKHHR"
     gene            complement(32875..33651)
                     /gene="yaaA"
                     /locus_tag="RN951_002037"
     CDS             complement(32875..33651)
                     /gene="yaaA"
                     /locus_tag="RN951_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HDX2527038.1"
                     /translation="MLILISPAKTLDYQSPLTTTRYTLPELLDNSQQLIHEARKLTPP
                     QISTLMRISDKLAGINAARFHDWQPDFTPENARQAILAFKGDVYTGLQAETFSEDNFD
                     FAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALA
                     AQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRF
                     IIENRLTKPEQLTGFNSEGYFFDEASSSNGELVFKRYEQR"
     gene            complement(33721..35151)
                     /locus_tag="RN951_002038"
     CDS             complement(33721..35151)
                     /locus_tag="RN951_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HDX2527039.1"
                     /translation="MPDFFSFINSVLWGSVMIYLLFGAGCWFTFRTGFVQFRYIRQFG
                     KSLKNSIHPQPGGLTSFQSLCTSLAARVGSGNLAGVALAITAGGPGAVFWMWVAAFIG
                     MATSFAECSLAQLYKERDVNGQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYGIIFSG
                     VQANAVARALSFSFDFPPLVTGIILAVFALLAITRGLHGVARLMQGFVPLMAIIWVLT
                     SMVICVINIGQLPHVIWSIFESAFGWQEAAGGAAGYTLSQAITNGFQRSMFSNEAGMG
                     STPNAAAAAASWPPHPAAQGIVQMISIFIDTLVICTASAMLILLAGNGTTYMPLEGIQ
                     LIQKAMRVLMGSWGAEFVTLVVILFAFSSIVANYIYAENNLFFLRLNNPKAIWCLRIC
                     TFATVIGGTLLSLPLMWQLADIIMACMAITNLTAILLLSPVVHTIASDYLRQRKLGVR
                     PVFDPLRHPDIGRQLSPDAWDDVSQE"
     gene            35430..36383
                     /gene="tal"
                     /locus_tag="RN951_002039"
     CDS             35430..36383
                     /gene="tal"
                     /locus_tag="RN951_002039"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HDX2527040.1"
                     /translation="MTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQ
                     IPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLS
                     YDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFS
                     FAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGY
                     ETVVMGASFRNIGEILELAGCDRLTIAPTLLKELAESEGAIERKLSYTGEVKARPARI
                     TESEFLWQHNQDPMAVDKLAEGIRKFAIDQEKLEKMIGDLL"
     gene            36498..37085
                     /gene="mog"
                     /locus_tag="RN951_002040"
     CDS             36498..37085
                     /gene="mog"
                     /locus_tag="RN951_002040"
                     /EC_number="2.7.7.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin adenylyltransferase"
                     /protein_id="HDX2527041.1"
                     /translation="MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELET
                     RLIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQ
                     MRQISLHFVPTAILSRQVGVIRKQALILNLPGQPKSIKETLEGVKDAAGNVVVHGIFA
                     SVPYCIQLLEGPYVETAPEVVAAFRPKSARRDVSE"
     gene            complement(37120..37686)
                     /gene="satP"
                     /locus_tag="RN951_002041"
     CDS             complement(37120..37686)
                     /gene="satP"
                     /locus_tag="RN951_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate uptake transporter"
                     /protein_id="HDX2527042.1"
                     /translation="MGNTKLANPAPLGLMGFGMTTILLNLHNVGYFALDGIILAMGIF
                     YGGIAQIFAGLLEYKKGNTFGLTAFTSYGSFWLTLVAILLMPKLGLTDAPNAQFLGVY
                     LGLWGVFTLFMFFGTLKGARVLQFVFFSLTVLFALLAIGNIAGNAAIIHFAGWIGLIC
                     GASAIYLAMGEVLNEQFGRTVLPIGESH"
     gene            complement(37835..38548)
                     /gene="msyB"
                     /locus_tag="RN951_002042"
     CDS             complement(37835..38548)
                     /gene="msyB"
                     /locus_tag="RN951_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acidic protein MsyB"
                     /protein_id="HDX2527043.1"
                     /translation="MNVNYLNDSDLDFLQHCSEEQLANFARLLTHNEKGKTRLSSVLM
                     RNELFKSMEGHPEQHRRNWQLIAGELQHFGGDSIANKLRGHGKLYRAILLDVSKRLKL
                     KADKEMSTFEIEQQLLEQFLRNTWKNMDEEHKQEFLHAVDARVNELEELLPLLMKDKL
                     LAKGVSHLLSSQLTRILRTHAAMSVLGHGLLRGAGLGGPVGAALNGVKAVSGSAYRVT
                     IPAVLQIACLRRMVSATQV"
     gene            complement(38574..38978)
                     /locus_tag="RN951_002043"
     CDS             complement(38574..38978)
                     /locus_tag="RN951_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2541 family protein"
                     /protein_id="HDX2527044.1"
                     /translation="MKSVFTISASLAISLMLCCTAQANDHKLLGAIAMPRNETNDLAL
                     KLPVCRIVKRIQLSADHGDLQLSGASVYFKAARSASQSLNIPSEIKEGQTTDWININS
                     DNDNKRCVSKITFSGHTVNSSDMATLKIIGDD"
     gene            39355..41271
                     /gene="dnaK"
                     /locus_tag="RN951_002044"
     CDS             39355..41271
                     /gene="dnaK"
                     /locus_tag="RN951_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HDX2527045.1"
                     /translation="MGKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQ
                     DGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAW
                     VEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRI
                     AGLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEV
                     LATNGDTHLGGEDFDSRLINYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA
                     QQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDI
                     DDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLL
                     DVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAAD
                     NKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLN
                     EDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIE
                     SALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQTAGADASANNAKDD
                     DVVDAEFEEVKDKK"
     gene            41360..42490
                     /gene="dnaJ"
                     /locus_tag="RN951_002045"
     CDS             41360..42490
                     /gene="dnaJ"
                     /locus_tag="RN951_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HDX2527046.1"
                     /translation="MAKQDYYEILGVSKTAEEREIRKAYKRLAMKYHPDRNQGDKEAE
                     AKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIF
                     GGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQT
                     CPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPA
                     GVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAAL
                     GGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLN
                     EKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR"
     gene            complement(42594..42746)
                     /gene="mokC"
                     /locus_tag="RN951_002046"
     CDS             complement(42594..42746)
                     /gene="mokC"
                     /locus_tag="RN951_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin MokC"
                     /protein_id="HDX2527047.1"
                     /translation="MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVF
                     TAYESE"
BASE COUNT        10333 a        10775 c        11694 g        10016 t
ORIGIN      
        1 gtctgtgccg aaccgtaggc cggataaggc gttcacgccg catccggcag ttggcgcaca
       61 atgcctgatg cgacgctgac gcgtcttatc atgcctacaa gtctgtgccg aaccgtaggc
      121 cggataaggc gttcacgccg catccggcag tcggcgcata atgcctgatg cgacgcttgt
      181 cgcgtcttat catgcctaca agtctgtgcc gaaccgtagg ccgtatccgg catgtcacaa
      241 atagagcgcc ggaaatatca accggctcac cccgcgcacc tttaacgcat cagccaacgg
      301 ctcaacgtct tccggcgtgg cgctcgccca gctttgcgcc tcgccataca cgccgtgggc
      361 atgaaacgca ttcaggcgaa ccggaacatc gccaagtctc ttgataaacg tcgccagctc
      421 atcgatgtga tgcaaataat ccacctggtc tggaattacc agcaaacgca gttccgccag
      481 cttaccgcgc tctgccagca aacagatgct gcgcttaatc tgctgattat cgcgtccggt
      541 taattgctga tgacattcgc tcccccacgc tttgagatcg agcattgcgc cgtcgcacac
      601 cgggagtaat ttttcccagc cggtttcgct caacataccg ttactgtcca ccaggcaggt
      661 gaggtggcgc agttgcggat cgtttttgat agcagtaaac agcgccacta caaacggcag
      721 ttgggtcgtg gcttcgccgc cgcttaccgt tatcccttca ataaacagca ccgctttgcg
      781 gacatggcta agcatttcgt ccacgctcat ggattgcgcc attggcgtgg catgttgcgg
      841 acacatcttc aggcaggtat cacactgctc gcagaccaca gcgttccaca gcactttgcc
      901 gtcaacaatc tgcaacgcct gatgcggaca ctgtggcacg cactctccgc aatcattgca
      961 gcgtcccatc gtccacggat tgtgacagtt tttgcagcgc agattgcagc cctgcaaaaa
     1021 cagagccaga cgactgcctg gcccgtcaac gcaggagaag gggataatct tactgactaa
     1081 agcgcatctg ctgttcatgg cttatcacgc gcggctggcg ttccagaata cgagtgttgc
     1141 gtgcggcttc ttcgcccagc caggtggtgt tggtgcgtga accttcggcg cgatattttt
     1201 ctaagtccga caaacgtacc atataaccgg taacgcgaac cagatcgtta ccgctgacat
     1261 tggcggtaaa ttcacgcatt ccggctttaa aggcaccgag gcaaagctgt accagtgcct
     1321 gcgggttacg tttgatggtt tcgtcgagcg tcagaatgtc gctgatgccg gaataataat
     1381 aagcatgatg cggggcgaca gtttgcagat gggtgatcgg atctggctca tcgccatacg
     1441 gcaaacgcgc gcccggcgtg gtgccaatat cggaactgat ccccgactgt gcgtgtaaca
     1501 tggcgcgttt ttgccagcca tatttcacgg gggtattggc gacaaactcc gccagttgcg
     1561 cgctgatgcg ataacccact tcatttgcgg cggcttcttt accgtagcgc gcggcaatcc
     1621 cttctttctc acacagcaag ttaaccgctt ccgctagccc atacatgcca aacattggca
     1681 caaaacgttc agggttaatc agcccttctt tcaccaggaa gctattctca aagaagtgtg
     1741 attgttgata gaggaattca caccgcgcat cgatgatggc gatctgctgc tggcagtagt
     1801 gcggtagagt gcgcgtaaag aagtcatcca gcgattcgct gcgctcggca atggctttca
     1861 ggttaaggcg taccagcgtg ctgccaccac ccgccagcgg cagtgagttg taacagctca
     1921 caatcccgta gccccctttt gtgaaaattt tatcatgcac cggaccgttg gcgatgtgcg
     1981 gtttgctaca ttcacagatg ttcttcgcca cttccagcag caggtcatca ggggtgattt
     2041 caggatcgta gataaaggtc aggttcggtg aaacctgctt caactctgcg tctgcacgta
     2101 agatcgcgcg ggtaatgggc gaatcagacg ggccgatatt ggcgtgcata aaggcgtctg
     2161 gcagggttct gtcgaggtaa cgccagaaac gttttattcg aacatcgatc tcgtcttgtg
     2221 ttagaattct aacatacggt tgcaacaacg catccagttg ccccaggtag accggcatcc
     2281 atgtgaccga cggtacgtgg tggtaaagaa tggtcagcag agagagtgcg tcatcaagat
     2341 ctttcgcgcc ttccagctcc agccattcgg aaccgttcgc cagaaaacgg gcgtaatcgg
     2401 gtaagacata gcgcggtttg tacggcgcat gaccttcaaa catatcgcag attacacctt
     2461 catccagcgc gcggcgggct tcggcaggca gctgtgggta aggcagattg ttttctgctt
     2521 ccagtgccag aaaatggcgc ttctgctccg ggctaagcac tgggctggtg acaatttgct
     2581 ggcaacgttg ttgcagtgca ttttcatgag aagtgggcat cttctgttcc tttttatgcc
     2641 gaaggtgatg cgccattgta agaagtttcg tgatgttcac tttgatcctg atgcgtttgc
     2701 caccactgac gcattcattt gaaagtgaat tatttgaacc agatcgcatt acagtaatgc
     2761 aattttgtaa gtagatttcc ttaattgtga tgtatatcga agtgtgttgc ggagtcgatg
     2821 ttagaatact aacaaactcg caaggtgaat tttattggcg acaagccagg agaatgaaat
     2881 gactgatctg aaagcaagca gcctgcgtgc actgaaattg atggacctga ccaccctgaa
     2941 tgacgacgat accgacgaga aagtgatcgc cctgtgtcat caggccaaaa ctccggtcgg
     3001 taataccgcc gctatctgta tctatcctcg ctttatcccg attgctcgca aaacgctgaa
     3061 agagcagggc accccggaaa tccgtatcgc tacggtaacc aacttcccac acggtaacga
     3121 cgatatcgaa atcgcgctgg ccgaaactcg cgcggcaatc gcctacggtg ccgatgaagt
     3181 tgatgtggtg ttcccgtacc gtgcactgat ggcgggtaac gagcaggttg gttttgatct
     3241 ggtgaaagcc tgtaaagagg cttgcgcagc agcgaacgta ctgctgaaag tgattattga
     3301 aaccggcgaa ctgaaagacg aagcgctgat ccgtaaagcg tctgaaatat ccatcaaagc
     3361 gggtgctgat ttcatcaaaa cctctaccgg taaagtagca gtgaacgcga cgccggaaag
     3421 cgcgcgcatc atgatggaag tgatccgtga tatgggcgta gagaaaaccg ttggtttcaa
     3481 accggcgggc ggcgtgcgta ctgcggaaga tgcgcagaaa tatcttgcca tcgcagatga
     3541 actgttcggt gctgactggg ctgatgcgcg tcattaccgc tttggtgctt ccagcctgct
     3601 ggcaagcctg ctgaaagctc tgggccacgg cgacggtaag agcaccagca gctactaagc
     3661 tgccttttgc cagagggtgg atgccggatg cggcggaacg ccttatccgg cctacgggtc
     3721 gagtgccgtg taggccttgt atgatgcgtc agcatcgcat caggcaataa caacatccgc
     3781 catctggcaa caacgccttc aaacttattc cacgggaggt taccttgttt ctcgcacaag
     3841 aaattattcg taaaaaacgt gatggtcatg cgctgagcga tgaagaaatt cgcttcttta
     3901 tcaacggcat tcgcgacaac actatctccg aagggcagat tgccgccctc gcgatgacca
     3961 ttttcttcca cgatatgaca atgccggagc gtgtctcgct gacgatggcg atgcgagatt
     4021 caggaaccgt tctcgactgg aaaagcctgc atctgaatgg cccgattgtt gataaacact
     4081 cgaccggcgg cgtcggcgat gtgacttcgc tgatgttggg gccaatggtc gctgcctgcg
     4141 gcggctatat tccgatgatc tccggtcgcg gcctcggcca tactggtggt acgctcgaca
     4201 aactggaatc catccctggc ttcgacatct tcccagatga caaccgtttc cgcgaaatta
     4261 ttaaagacgt cggcgtggcg attattggcc agaccagttc actggctccg gcggataaac
     4321 gtttctatgc gacccgcgat attaccgcaa ccgtggattc catcccgctg atcactgcct
     4381 cgatcctggc gaagaaactg gcggaaggtc tggatgcact ggtgatggac gtgaaagtcg
     4441 gtagcggtgc atttatgtcg acctacgaac tctctgaagc ccttgccgaa gcgattgttg
     4501 gcgtggctaa cggcgctggc gtgcgcacca ccgcgctact caccgacatg aatcaggtgc
     4561 tggcctccag tgccggtaac gcggttgaag tacgtgaagc ggtgcagttc ctgacaggtg
     4621 agtaccgtaa cccgcgtctg tttgatgtca cgatggcgtt gtgtgtggag atgcttacct
     4681 ccggcaaact ggcgaaagat gacgccgaag cgcgcgcgaa attgcaggcg gtactggaca
     4741 acggtaaagc ggcagaagtc tttggtcgta tggtagcggc acaaaaaggc ccgaccgact
     4801 tcgttgagaa ctacgcgaag tatctgccga cagcgatgct gacgaaagca gtctatgctg
     4861 ataccgaagg ttttgtcagt gatatggata cccgcgcgct gggaatggca gtggttgcaa
     4921 tgggcggcgg tcgccgtcag gcatctgaca ccatcgatta cagcgtcggc tttactgata
     4981 tggcgcgttt gggtgaccag gtagacggtc agcgtccgct ggcggttatc cacgcgaaag
     5041 acgaaaacag ctggcaggaa gcggcgaaag cggtgaaagc ggcaattaaa cttgccgata
     5101 aagcaccgga aagcacacca actgtctatc gccgtatcag cgaataacgg tatactgatc
     5161 tgatcattta aatttgaagc actgagtacg gagaacatat gaaacgtgca tttattatgg
     5221 tgctggactc attcggcatc ggcgctacag aagatgcaga acgctttggt gacgtcgggg
     5281 ctgacaccct gggtcatatc gcagaagctt gtgccaaagg cgaagctgat aatggtcgta
     5341 aaggcccgct caatctgcca aatctgaccc gtctggggtt ggcgaaagca cacgaaggtt
     5401 ctaccggttt cattccggcg ggaatggacg gcaacgctga agttatcggc gcgtacgcat
     5461 gggcgcacga aatgtcatcc ggtaaagaca ccccgtctgg tcactgggaa atcgccggtg
     5521 tcccggttct gtttgagtgg ggatacttct ccgatcacga aaacagcttc cctcaagagc
     5581 tactggataa actggtcgaa cgcgctaatc tgccgggtta cctcggtaac tgccactcct
     5641 ccggtacggt cattctggat cagctgggcg aagagcacat gaaaaccggc aagccgattt
     5701 tctatacctc cgctgactcc gtgttccaga ttgcctgcca tgaagaaact ttcggtctgg
     5761 ataaactcta cgaactgtgt gaaatcgccc gtgaagagct gaccaacggc ggctacaaca
     5821 tcggtcgtgt tatcgctcgc ccgtttatcg gcgataaagc cggtaacttc cagcgtactg
     5881 gcaaccgtca cgacctggct gttgaaccgc cggcaccgac cgtgctgcag aaactggttg
     5941 atgaaaaaca cggccaggtg gtttctgtcg gtaaaattgc agacatctac gctaactgcg
     6001 gcatcaccaa aaaagtgaaa gcgaccggcc tggacgcgct gtttgacgcc accattaaag
     6061 agatgaaaga agcgggtgat aacaccatcg tcttcaccaa ctttgttgac ttcgactctt
     6121 cctgggggca ccgtcgcgac gtcgcaggtt atgcggcggg tctggaactg ttcgaccgcc
     6181 gtctgccaga gctgatgtct ttgctgcgcg atgacgacat cctgatcctc accgctgacc
     6241 acggttgtga tccgacctgg accggtactg accatacccg tgaacacatt ccggtactgg
     6301 tttacggccc gaaagtaaaa ccgggttcgc tggggcaccg tgaaactttc gcggatatcg
     6361 gccagactct ggcaaaatat tttggtactt ctgatatgga atatggcaaa gccatgttct
     6421 gatggatttg ggcggagcag tgactccgcc tttaatatgt cacaaaaagg ataaaatgat
     6481 ggctactcca cacattaatg cagaaatggg cgatttcgct gacgtagttt tgatgccagg
     6541 cgacccgctg cgtgcgaagt atattgctga aactttcctt gaagatgccc gtgaagtgaa
     6601 caacgttcgc ggtatgctgg gtttcaccgg tacttacaaa ggccgcaaaa tttctgtaat
     6661 gggccacggt atgggtatcc cgtcctgctc catctacact aaagaactga tcaccgattt
     6721 cggcgtgaag aaaatcattc gcgttggttc ctgtggtgca gttctgccgc acgtaaaact
     6781 gcgtgacgta gtgattggta tgggtgcctg caccgattcc aaagttaacc gcatccgttt
     6841 taaagaccat gactttgcag ctatcgctga cttcgacatg gtgcgtaacg cggtagatgc
     6901 agctaaagca ctgggcattg atgctcgcgt tggtaacctg ttctccgctg acctgttcta
     6961 ctctccggac ggcgaaatgt tcgacgtgat ggaaaaatac ggcatcctcg gcgtggaaat
     7021 ggaagcagct ggtatctacg gcgtcgctgc agaattcggc gcgaaagccc tgaccatctg
     7081 caccgtatct gaccatatcc gcacgcacga gcagaccact gccgctgagc gtcagactac
     7141 cttcaacgac atgatcaaaa tcgcactgga atccgttctg ctgggcgata aagagtaatt
     7201 gtgtttcgct gaaaggcgat tgtcgtgtga agccggagcg ggagaccgct ccggcttttt
     7261 agcatctatt catttttctc tccagcttga atattttcgc tatacttttc agtgaaatgt
     7321 gttaataaat ctattcaagt atctattcac gaatctattc attaatgagc gaactgaccg
     7381 atcttttact gcaagggccg cgttctgccc cggaattgcg ccagcgtctg gcaatcagtc
     7441 aggcgacgtt ctcacgtctt gttgccagag aagatcgggt gattcgcttt ggcaaagcac
     7501 gggcaacgcg atatgcactg ctgcgtcctt atcgcggaat tgaacgtatt ctcgtctggc
     7561 gggtggacga tgccggaaag gcgcataaat tcgccgacat ccagttgtgc tggccgcagg
     7621 gaagttgtct ggtcacaggc ggaaagggcg acgaacagtg gtttgatggt ttgccctggt
     7681 atttgaccga tctccgacca caggggtttt tggggcgcgc gtggggcaga aatttagccg
     7741 gacaactgaa tctgactgaa gatatacgtc tctggcagga agaagatgtg ctctacgccc
     7801 tgaccgtatt taacggtgaa tataccgggg gctggctggt cggggagagg aattatcagc
     7861 gatggattac tgcaccacgc cctgcggcaa ttcctctgga tcaaaaactc acccgttacg
     7921 aacaactggc gcatgatgca ctggcaggag aaattgtggg ttcttctgcg ggcggcgagc
     7981 agccaaaatt tacctgctat gtacaaacgc cgtcaggcaa taaacatgtg ttggtgaaat
     8041 tcaccgtgcc acagcaaacc gcggtcagcc aacgttgggg tgacctgcta attgctgaat
     8101 ctattgccgc gcaaatcctg tgcgacggtg ggatccacgc catcgagtca acggtgcttg
     8161 taacaagtaa caggcaggta ttccttgaag cggaacgctt tgactgtaaa ggtaacgatg
     8221 gtcgcttgcc cattgtgtcg ctggaggcgg tgcagagtga gtttatctct tctccgggat
     8281 cgtggccgga ggcaatgcgc cgtttgtgtg agcaacaatt tgtcactcac cagagcgtgg
     8341 cgcaaacaga agtgatctgg gcgtttgggc gacttatcgc caacagcgat atgcacgcag
     8401 gcaatttatc attttattta tctgaaccac catttgcgct gacgcccgtc tacgacatgc
     8461 tgccgatggc ctatgcacca aacagcgccg gaatgctgcg tgatgctgcc attgaggtga
     8521 agtttgatct taacgtcagt aaaagcgcat ggttaacggc gatcccgctg gcgcagcagt
     8581 tctggcaaac ggtcgctgga gatccgcgta tcagcgaggc gtttcgccac attgcgcagg
     8641 aaatgccgga aaaaatccgg caaatcgaag ggaaagttgc ccgcatgggc gggtaactac
     8701 cgtaccgctc ccgctatcca cgccgacaac tcccgtagct ctttttcctg ttcagggaag
     8761 tcaaccaaca gcgcttcaca ctcttgttgc agcatgtcag cgcggtatag gcagccttgc
     8821 agtcgtccgg cgagagcttc cagaggtgcg gggttgaggc tatcggtaaa cacctgggtg
     8881 cgggtgatat ggcctttttc gacgtcgaaa tgcagttcta cgccgcccca ggtaaagcgt
     8941 tcatccagca gatgcgaaaa cgccggagcc tgaccgaagt tccattccca gctactctgg
     9001 cgggcaaagg tttcggcaaa gttcggcaag tctggcgttt tgtccggtga gatgatttcc
     9061 gcttctgtgc gctcgccata atgtgcgaaa aaggtttcgg atatggcctc gcaaacctgc
     9121 tcatgggtaa ttcccggcag caattcggtc agattggtca cgcgggaacg taccgacgta
     9181 atgcctttcg ccgccagttt ctttttatcc gggttgagat agtttgccag gcggctaagg
     9241 tcggcattga gtagcaaggt gccgtggtgg aagccacgat ctttggtttc gcgataggcc
     9301 gagcctgaga ctttacggtc gccttcggcg gttttcacca ccaaatcgtt acgtccggac
     9361 gcttcggcgc tgacaccgag cgcgttcagt gcattgagca caatcgaggt ggagatcgtt
     9421 ttatcgtatt ccggcttgcc agccatgaag gtaaaacagg tattgccgag atcgtggaac
     9481 accgcgccgc caccgctact gcgccgtgcc aggcggacgt tatcttcttc catccgccgg
     9541 gtattacact ctttccacgg gttctgcgcg cgaccaatca ctaccgtgtc ggcattgcgc
     9601 cagagaaaca gaacgcgctg cgtggcgggc atctggcgaa aaatacactc ctccaccgcc
     9661 aggttaaacc acgggtcgta agagtcagag atgagcaggc gtaatgtgga cataacgatt
     9721 tcctttcttg tagtaatggg tcactctttt ttctcgcttt cttcctcttc cggcaccggt
     9781 ttgctggcgg ttaacaggaa gggcgattgc tgccagcggg tacgtttacc ctgtagcagc
     9841 gtgcgggtca gcactacgcc gattgccagt gaaagcagca acatcaggcg taaaatgtta
     9901 gtggtgttat ccacctgttg ggcttcggtg gcgagcgtat gggtgtcgag cgtcaggcgc
     9961 agatagccga gcggtccgtt tttcccggca attggttcga caatctgctg gttaaaatag
    10021 ccgcccgctt ttttaccgtc gagcgccagc cggtcgcgca cttcgacgct ttcgccagaa
    10081 cgggcgataa gatcgccttg ttcgtcatac acgcccgcgt cgaggatacg gctttcatcc
    10141 gttaactgat cgaggatcgc ctgaatgcgt ttttcatccg gcgagtcggt acgcatcagc
    10201 ggtgcaacgt tcagcgttac ctgacgcgcc agggtgcggg ccagttcttc cagctgtgga
    10261 ttacgttgtc gctggtggtt ttgactaaac catgacgctc cctgcatcag cgccactaac
    10321 aaggcaagac agaacaggac aatcactgcc cgatgcagcc ggaatttcag ttttgtgcga
    10381 gccatcttcc accctttgaa aatttgagac ttaatgttgc cagaagcaat ggatacaagg
    10441 tagcctcatg cgttattttc cctgcttcga acgattttac aggagcctta atgcctaaca
    10501 ttacctggtg cgacctgcct gaagatgtct ctttatggcc gggtctgcct ctttcattaa
    10561 gtggtgatga agtgatgcca ctggattacc acgcaggtcg tagcggctgg ctgctgtatg
    10621 gtcgtgggct ggataaacag cgtctgaccc aataccagag caaactgggt gcggcgatgg
    10681 tgattgttgc cgcctggtgc gtggaagatt atcaggtgat tcgtctggca ggttcactca
    10741 ccgcacgggc tacgcgcctg gcccatgaag cgcaactgga tgtcgccccg ctggggaaaa
    10801 tcccgcacct gcgcacgccg ggtttgctgg tgatggacat ggattccacc gccatccaga
    10861 ttgaatgtat tgatgaaatt gccaaactgg ccggaacggg cgagatggtg gcggaagtaa
    10921 ccgaacgggc gatgcgcggc gaactcgatt ttaccgccag cctgcgcagc cgcgtggcga
    10981 cgctgaaagg cgctgacgcc aatattctgc aacaggtgcg tgaaaatctg ccgctgatgc
    11041 caggcttaac gcaactggtg ctcaagctgg aaacgctggg ctggaaagtg gcgattgcct
    11101 ccggcggctt tactttcttt gctgaatatc tgcgcgacaa gttgcgcctg accgccgtgg
    11161 tagccaatga actggagatc atggacggta aatttaccgg caatgtgatc ggcgacatcg
    11221 tagacgcgca gtacaaagcg aaaactctga ctcgcctcgc gcaggagtat gaaatcccgc
    11281 tggcgcagac cgtggcgatt ggcgatggag ccaatgacct gccgatgatc aaagcggcag
    11341 ggctggggat tgcctaccat gccaagccaa aagtgaatga aaaggcggaa gtcaccatcc
    11401 gtcacgctga cctgatgggg gtattctgca tcctctcagg cagcctgaat cagaagtaat
    11461 tgctcgcccg ccatcctgcg ggcggcacag cattaacgag gtacaccgtg gcaaaagctc
    11521 caaaacgcgc ctttgtttgt aatgaatgcg gggccgatta tccgcgctgg caggggcagt
    11581 gcagtgcctg tcatgcctgg aacaccatca ccgaggtgcg tcttgctgcg tcgccaacgg
    11641 tggcgcgtaa cgagcgtctc agcggctatg ccggtagcgc cggggtggca aaagtccaga
    11701 aactctccga tatcagcctt gaagagctgc cgcgtttttc caccggattt aaagagttcg
    11761 accgcgtact aggcggcggc gtggtgccag gaagtgccat tctgattggc ggtaaccctg
    11821 gtgcggggaa atccacgctg ttgctgcaaa cgctgtgcaa actggcccag cagatgaaaa
    11881 cgctgtatgt caccggcgaa gagtcgctgc aacaggtggc aatgcgcgct catcgccttg
    11941 gcctgccgac tgacaatctc aatatgttgt cggaaaccag catcgagcag atctgcctga
    12001 ttgccgaaga agagcaaccg aagctgatgg taattgactc gatccaggtg atgcatatgg
    12061 cggatgtaca gtcatcgcct ggcagcgtgg cgcaggtgcg tgaaacggcg gcttatctga
    12121 cgcgcttcgc caaaacgcgc ggtgtggcga ttgtcatggt tgggcacgta accaaagatg
    12181 gctcgctggc tggccctaaa gtgctggaac actgtatcga ctgttcggtg cttctggatg
    12241 gtgatgccga ctcccgtttt cgcaccttgc gcagccataa aaaccgcttc ggcgcggtga
    12301 atgagctggg cgtcttcgcg atgaccgaac aggggctgcg tgaagtcagc aacccttcgg
    12361 caattttctt aagtcgcgga gatgaagtga cctccggcag ctccgtgatg gtggtgtggg
    12421 aaggaacgcg tccgttgctg gtggagattc aggcgctggt cgatcactcg atgatggcga
    12481 atccgcgccg cgtggcagtg gggctggaac aaaaccgtct ggcaatcctg ctggctgtct
    12541 tgcaccgtca cggtggtctg caaatggccg atcaggatgt atttgtgaac gtggtcggcg
    12601 gcgtgaaggt aaccgaaacc agtgccgatt tagctttact gctggcgatg gtttccagcc
    12661 tgcgtgacag accgctgcca caggatctgg tggtgtttgg tgaagtcggg ctggcagggg
    12721 agatccgccc ggtgcccagc ggtcaggaac gaatttcaga agcggcgaaa cacggttttc
    12781 gccgggcgat tgttccggcg gctaacgtac cgaaaaaagc gccggaaggg atgcagattt
    12841 ttggcgttaa aaaactctcc gacgcgctta gcgtgttcga cgacttataa tgagagatac
    12901 ggagggagat atgtcgtcat ttgattacct gaaaactgcc atcaagcaac agggctgcac
    12961 gctacagcag gtagctgatg ccagcggtat gaccaaaggg tatttaagcc agttactgaa
    13021 tgccaaaatt aaaagcccca gcgcgcaaaa gctggaggcg ttgcaccgtt ttttggggct
    13081 tgaatttccc cgacagaaga aaaccattgg tgtcgtattc ggtaagttct acccgctgca
    13141 taccggacat atctacctta tccagcgcgc ctgtagccag gttgacgagc tgcatatcat
    13201 tatgggtttt gacgataccc gcgaccgcgc gttgtttgaa gacagcgcca tgtcgcagca
    13261 gcccacggtg ccggatcgtc tgcgctggtt attacaaact tttaaatatc agaaaaatat
    13321 tcgcattcat gctttcaacg aagagggcat ggagccgtat ccgcacggct gggatgtgtg
    13381 gagcaacggc atcaaaaagt ttatggctga aaaggggatt cagccggacc tgatctacac
    13441 ctcggaagaa gccgatgcgc cacagtatat ggaacatctg gggatcgata cggtgctggt
    13501 cgatccgaaa cgtaccttta tgagtatcag cggtgcgcag atccgcgaaa acccgttccg
    13561 ctactgggaa tatattccta cggaagtgaa gccgttcttt gtacgtaccg tggcgatcct
    13621 tggtggcgag tcgagcggta aatccaccct ggtaaacaaa cttgccaata tcttcaatac
    13681 caccagtgcg tgggaatatg gtcgcgatta tgtcttttca cacctcggcg gtgatgagat
    13741 cgcattgcag tattccgatt acgataaaat cgcgctgggc cacgcacaat acattgattt
    13801 tgcagtgaaa tatgccaata aagtggcgtt tattgacact gattttgtca ctacccaggc
    13861 gttctgcaaa aagtacgaag ggcgtgagca tccgttcgta caggcgttga ttgatgaata
    13921 ccgtttcgat ctggtgatcc tgctggagaa caacacgccg tgggtggcgg atggtttacg
    13981 cagcctcggc agttcggtgg atcgcaaaga gttccagaac ttgctggtgg agatgctgga
    14041 agagaacaat atcgaattcg tgcgggttga agaggacgat tatgacagcc gtttcctgcg
    14101 ctgcgtggag ctggtgcggg agatgatggg ggagcagaga taaccgcgat gaaacggctc
    14161 aaaggcgagg tataaaataa gttttttgat gagttgaaaa cctctctgga agaggctgtc
    14221 gagattaaac aaggtttgaa aaaacctgca cgggtgaccc gctacgaaat tgcggatact
    14281 aaggctgttg taggccggaa aaggcgttca cgccgtatcc ggcattcggt gctcaatgcc
    14341 tgatgcgacg cttaccgcgt cttatcaggc ctggagattc acaacgtatt gaaatttctt
    14401 ggtttgtagg ccggataagg cgttcacgcc gcatccggca ttttacgcat tacttcgcaa
    14461 tacgcttgta cttgatacgc ttcggctcca gtgcgtctgc gcccagcgtg cgtttcttgt
    14521 actcttcgta ctcagtaaag ttaccttcga agaactcaac tttaccttca tcctggtagt
    14581 ccaggatgtg cgtggcgata cggtcgagga accaacggtc gtgcgagata accatcgcac
    14641 agcccgggaa ctccagcagg gcgttttcca gcgcgcgcag ggtttcgata tccaggtcgt
    14701 tggttggttc gtcgagcagc agcatgttgc cgccaacctg cagcagcttc gccagatgca
    14761 gacgaccgcg ctcaccaccg gaaagttcac caacgcgttt accctgatca acccctttaa
    14821 agttaaagcg gccaacgtag gcgcggcttg gcatctcggt gttgccgatc ttcataatat
    14881 ccagcccgcc ggaaacttct tcccaaacgg ttttgctgtt atccattgag tcacggaact
    14941 gatcaaccga tgccagtttc accgtttcac ctaaagtgat ggtgccgctg tccggctgtt
    15001 cctgaccaga gatcatacgg aacagggtcg atttacccgc gccgttcgga ccgatgatcc
    15061 cgacgattgc ccctttcggg atcgagaagc tcaggtcatc aatcagcagg cgatcaccgt
    15121 aggatttacg caggttgctg acttccagca ctttatcgcc cagacgcggt ccaggtggaa
    15181 taaacagttc gttggtttcg ttacgtttct gatattcggt gctgttcagc tcttcaaagc
    15241 gtgccagacg tgctttacct ttcgactggc ggcctttagt tccctgacgt acccactcca
    15301 gctctttctc gatcgactta cgacgcgccg cttcttgtga agcttcctgc gccaggcgct
    15361 gatctttctg ctccagccag gaggagtagt tgccttccca cggaatacct tcaccgcggt
    15421 caagttcgag gatccagcct gcaacgttat cgaggaagta acggtcgtgg gtaatcgcca
    15481 ccacggtgcc ctcgaagtcg tgcaggaagc gttccagcca ggccacggat tcggcatcca
    15541 ggtggttggt cggttcgtcg agcagcagca tgtctggttt ttccagcagc aggcggcaca
    15601 acgctacgcg acgacgctca ccaccggaga ggttagcgat tttcgcgtcc cagtccggca
    15661 gacgtagcgc atccgccgca cgctccagct gtacgttcag gttatgaccg tcgtgagcct
    15721 gaatgatctc ttccagacgg ccttgttcag cggccagctt gtcaaaatcg gcatccggat
    15781 cggcgtacag cgcatacact tcatccaggc gtttcagggc gttaaccact tcagaaaccg
    15841 cttcttcaat ggactcacgc acggtgtgtt ccgggttcag ctgcggttcc tgcggcaggt
    15901 aaccaatctt gatgtctggc tgcggacgcg cttcaccttc gatgtcttta tcaatgcccg
    15961 ccataatgcg cagcagggta gacttacccg cgccgttcag acccaggaca ccaatttttg
    16021 ccccagggaa gaaactcaga gagatgtttt tcaaaatatg acgtttcggc ggaacaactt
    16081 tgccgacacg atgcatggta taaacgaatt gagccacgtt ggacttcgcc tctatgttta
    16141 tcgtgatgat gagttttcaa aggcgaagtg tagccttttt ccccgcctaa tcccagttgg
    16201 tcgatcacct tcgcagtaaa agtaaaaaag tgtccgtaac gtggcgtaaa cggcaatgac
    16261 tggttagcat aaatctatta cgcggcatga cgctgcattg atgtatttac acttagagga
    16321 tgcgcttgtg gaaaaagcca aacaagttac ctggcggctg ttggctgccg gtgtctgtct
    16381 gctgacggtc agcagcgtgg cgcgagccga ctcactggat gagcagcgta gccgttacgc
    16441 gcaaatcaag caggcctggg ataatcgaca aatggatgtg gtcgaacaaa tgatgcctgg
    16501 actgaaagat tatccacttt atccctacct ggaataccgt cagatcaccg atgacctgat
    16561 gaatcaaccg gcggtgacgg tcactaactt tgttcgcgct aaccccacgc ttcctcccgc
    16621 tcgcacgctg caatctcgtt tcgtcaatga actggcgcgg cgtgaagact ggcgtggctt
    16681 gttagccttt agcccggaaa agcccggaac taccgaagcg caatgtaatt actactatgc
    16741 aaaatggaac accgggcaga gtgaagaagc ctggcaaggg gcgaaagagc tgtggctaac
    16801 cggcaagagc cagcctaacg cctgtgacaa gttatttagt gtctggcgtg cgtcaggtaa
    16861 acaagatccg ctggcgtatt tagagcgtat ccgtctggcg atgaaagcgg gtaacactgg
    16921 cctggtaaca gtgctggcag ggcagatgcc tgccgattac cagactatcg cctcggcaat
    16981 catttcactg gcgaacaacc ctaatacggt actgaccttc gcgcgtacaa ccggagcgac
    17041 cgattttacc cgtcaaatgg cggcggtggc gtttgccagt gtggcgcggc aggatgctga
    17101 aaatgcacgg ctgatgatcc catcgcttgc ccaggcgcag cagcttaatg aagatcagat
    17161 tcaggagctg cgcgatatcg tcgcctggcg tttgatgggc aacgatgtca ccgacgagca
    17221 ggcgaaatgg cgcgatgacg ccattatgcg ctcgcaatct acttcgctta ttgaacgccg
    17281 tgtacgaatg gcgcttggca ccggcgatcg tcgcggcctg aatacctggc tggcgcgttt
    17341 gccgatggag gcgaaagaga aagatgaatg gcgttactgg caggcggatt tactgctgga
    17401 acgcggacgt gaagctgaag caaaagagat tttgcatcaa ctcatgcaac agcgtggttt
    17461 ctacccgatg gttgctgcac aacgcatcgg cgaagagtat gagctgaaga ttgataaagc
    17521 gccgcagaat gttgacagcg ccctgactca ggggtcggag atggcgcgcg tgcgcgagtt
    17581 gatgtactgg aatctcgata acaccgcgcg tagcgagtgg gccaatctgg tgaagagcaa
    17641 gtcaaaaaca gagcaggctc aactggcgcg gtatgctttc aacaaccaat ggtgggatct
    17701 tagcgttcag gcaacgatcg ccgggaagct gtgggatcat ctggaagagc gattcccgct
    17761 ggcttacaac gatcttttca aacgttacac cagtgggaag gagatcccgc aaagctatgc
    17821 gatggcgatt gcccgtcagg agagcgcctg gaatccaaaa gtgaaatcac cggtaggggc
    17881 cagcggcctg atgcagatta tgcctggtac agcgacccat acggtgaaga tgttctctat
    17941 tcctggttat agcagccctg ggcaattgct ggatccggaa acgaatatca acattggcac
    18001 cagttatctg caatatgttt atcagcagtt tggcaataac cgtattttct cctcagcagc
    18061 ttataacgcc ggaccagggc gggtgcgaac ctggcttggc aacagcgccg ggcgtatcga
    18121 cgcagtggca tttgtcgaga gtattccgtt ctccgagacg cgtggttatg taaagaacgt
    18181 gctggcttat gacgcttact accgctattt catgggggat aaaccgacgt tgatgagcgc
    18241 cacggaatgg ggacgtcgtt actgatccgc ccgtttatga tatgctatcg tactctttag
    18301 cgagtacaac cgggggaggc attttgcttc ccccgctaac aatggcgaca tattatggcc
    18361 caacaatcac cctattcagc agcgatggca gaacagcgtc accaggagtg gttacgtttt
    18421 gtcgacctgc ttaagaatgc ctaccaaaac gatctccatt taccgttgtt aaacctgatg
    18481 ctgacgccag atgagcgcga agcgttgggg actcgcgtgc gtattgtcga agagctgttg
    18541 cgcggcgaaa tgagccagcg tgagttaaaa aatgaactcg gcgcgggcat cgcgacgatt
    18601 acgcgtggat ctaacagcct gaaagccgcg cccgttgagc tgcgccagtg gctggaagag
    18661 gtgttgctga aaagcgattg attttgtagg cctgataaga cgcggcagcg tcgcatcagg
    18721 catcgtgcac cgaatgccgg atgcggcgtg aacgccttat ccgtcctaca atgcctgata
    18781 tacggcattg tgaaacggac tcagcgccag gatcaccgcc tggtgataga cgctggcgcg
    18841 agtgagtttc ccggcggtaa acacgccgat cgccccttcc ttacgaccaa tctcatcaat
    18901 accggtataa cgcgacatca cgggaccaag cgcctcgcct tcacgcactt tttccagaat
    18961 caccgcaggc aacggcaaag tagccgaacg cgcctcgccg cgctggctgg cgttttcaat
    19021 caccacccaa ctgaaagtgc tgtcaccatc gatgccagct tcaatcgcca cccaaaaatc
    19081 agcctctgga agtaaacggc gggcatttgc tacccgattt cgtgcgccag cgcgcgtttc
    19141 ctcactgcca aagggttgtt ccggtacacc gctctcgacg gcaacggatg caatatggca
    19201 ggatccttcg ccgaagatct cgtgaaatgc ctgcagaatg gcctgaattt tagcgggatt
    19261 ggtggtcgca cagacaactt ggtgcataat cagcattact cagaaaatta acgttacagc
    19321 agtatacgga aaaaaagcat gttacaggta tacctagtcc gccacggtga aacgcagtgg
    19381 aacgccgagc gacgtattca gggccagtct gacagcccgc tgaccgccaa aggtgagcaa
    19441 caggcgatgc aggtggcaac ccgtgccaaa gagcttggca ttacgcatat tatcagtagc
    19501 gatttaggac gcacccggcg tacggcggaa atcatcgccc aggcctgcgg ctgtgacatc
    19561 atctttgatt ctcgcctgcg tgaattaaac atgggtgtgc tggaaaaaag acatatcgat
    19621 tctctgaccg aagaagaaga gaactggcgt cggcagctgg tcaatggcac cgttgacggg
    19681 cgtattcctg aaggcgagtc aatgcaggag ctcagcgatc gcgtcaatgc ggcactggaa
    19741 tcttgccggg acttaccgca gggaagccga ccgctgctgg tgagtcatgg tattgcactg
    19801 ggatgcctgg tgagtacgat tctcggatta ccagcatggg cagagcgccg cttacgtctg
    19861 cgtaactgtt ctatttcgcg cgtggattat caggaaagcc tgtggctggc gtctggctgg
    19921 gtcgttgaaa ccgcagggga catctcgcat ctggacgccc ctgcattaga tgagctgcag
    19981 cgttaacggc ggataggaat cagcagttca cagcgcagat taattgggcg atctcccgct
    20041 ttggcgtctt ctgccgggta gtatcgctca atatcctgac ctttacggcg cgtcaggttg
    20101 agcattggca tgcacgttcc gtataccgtc aggataaact cctgcacgcc ggttcccaga
    20161 ccttcatagg taaacatcac atattcgccg ccctgcagca tcaccggatg ccccgtcagt
    20221 acatagccat ctgcctgatc ctgggctaac gcggtggtat agaatacctc ttgttcgtcg
    20281 tctttatcct gactcggacg cgtttcattc aggccgtaga gcactggcgg aatggtcggc
    20341 gcgttgccga gaaaatcgtg ccagaactga taacgcattt catggcggaa atcagagatt
    20401 tgctccagcg aacaggagta gctctgggta acaccaatca gcggcgtatc ttccagggtg
    20461 acaaatttat gctctggcat agtgaattca cccagacgca gcggcgggcg aataccaaag
    20521 gcgctccatt caggagaacg gcggtaaagt gcaggagtct gggcaaactg cttcttgaat
    20581 gcgcgggtaa atgtctgttg agagtcgaag cggtattgca gcgcgatgtc cagaatcgga
    20641 cgcgcagtca ggcgtagtgc gaccgccgat ttcgacaaac gacgagcacg aatatacgcg
    20701 ccaatagcat ggccagtgac atctttaaac attctctgta agtgccactt ggaataacct
    20761 gctttcgccg ctacattgtc gagcgacagg ggctgatcca gatgaccttc cagccagatt
    20821 aaaaggtcgc gaataatgcc ggcctgatcc ataaaatatc ctcatccttt caacaacgag
    20881 cacctgacat caggtaattg gataatagca ttttttgctg ttttagcatt cagtgttttt
    20941 ttcttagtag agtatgtttt aggtcttgac ggaaataaaa gtattgagat tttgttctta
    21001 atcaatatgt tatttaccgt gacgaactaa ttgctcgtgt aatagataaa aatggtaaca
    21061 atatgaaata caagcatttg atcctgtctt taagcctgat aatgctgggg ccattggctc
    21121 atgcagaaga gattggttcg gtcgacaccg tatttaaaat gatcggcccg gatcacaaaa
    21181 ttgttgtgga agcctttgac gatcccgatg tgaaaaatgt cacctgttat gtgagccggg
    21241 cgaaaacagg tggtattaaa gggggattgg gtctggcgga agatacctcc gatgcggcta
    21301 tttcttgtca gcaagtcggg ccgattgaac tgtcggatcg tattaaaaac ggcaaagctc
    21361 agggcgaggt agtattcaaa aaacgcacgt ccctggtctt taagtcgtta caggtcgtgc
    21421 gcttttatga cgccaaacgc aacgcgctcg cttatctggc ttactccgac aaagttgtag
    21481 aaggttcgcc gaaaaacgcg attagcgcgg ttcctgtcat gccgtggcgg caataacaga
    21541 ggcgatttat gcaacgggaa acggtctggt tagtggaaga tgagcaaggg atagccgaca
    21601 cgctggtcta catgttgcag caggaaggtt ttgccgtcga ggtctttgag cgaggcttgc
    21661 cggtgctgga taaagctcgc cagcaggctc ccgacgtcat gattctcgat gttggtttgc
    21721 ctgatatcag cggctttgaa ttatgccgcc agttactggc gctccatccg gcgttacctg
    21781 tactgttcct gacggcccga agtgaagagg tcgatcgcct gcttgggctg gaaattggcg
    21841 ctgacgacta tgtggctaaa ccgttttcac cccgcgaagt gtgcgccagg gtgcgcacct
    21901 tactgcgtcg ggtgaagaag ttctcgtcgc cgtctcccgt catccgtatt ggtcattttg
    21961 aattgaatga acccgcggcg cagatcagct ggtttgacac gccattaacg ctgacgcggt
    22021 atgagttttt attgctgaag acgttactca agtcgccagg ccgcgtctgg tcccgccagc
    22081 aactaatgga tagcgtgtgg gaagatgcgc aggacaccta cgatcgcacc gttgataccc
    22141 acattaaaac gttgcgtgcc aagctgcgcg ccatcaaccc cgatctttca ccgattaata
    22201 ctcatcgcgg catgggatat agcctgaggg gcctgtaatg cgtatcggca tgcggttgct
    22261 gctgggctat tttttactgg tggcggtggc ggcctggttc gtactggcta tttttgtcaa
    22321 agaagttaaa ccgggcgtgc gaagagcaac ggaggggacg ttaatcgata ccgcaacgtt
    22381 gctggcggag ctggcgcgtc ccgatttgct ctctggggac ccaacgcatg ggcaactggc
    22441 gcaggcgttt aatcagctac aacatcgccc gtttcgcgcc aatatcggtg gcattaacaa
    22501 agtgcgcaat gaatatcatg tctatatgac cgattcgcag ggtaaagtat tgttcgattc
    22561 ggcaaataaa gccgttgggc aggattattc gcgctggaat gacgtctggc taacgttgcg
    22621 tggtcagtat ggtgcgcgca gcacgttgca aaatcctgcc gatcccgaaa gttcggtgat
    22681 gtatgttgcc gcgccgatta tggacggctc gcggcttatt ggcgttttga gcgtaggcaa
    22741 accgaacgcg gcgatggctc cggtcattaa gcgtagcgag cggcgaattt tatgggccag
    22801 cgccattttg ctggggattg cactggtgat tggcgcaggc atggtttggt ggatcaaccg
    22861 ctccattgcc cggctcactc gctatgccga ttccgtcact gacaataagc ccgttcctct
    22921 tcctgaactc ggcagtagcg agttgcgtaa gcttgcgcag gcgctggaaa gtatgcgcgt
    22981 gaagctggaa gggaaaaact atattgagca gtatgtttat gcgttaaccc atgagctaaa
    23041 aagcccactg gcggcgattc gtagcgcggc ggaaatttta cgcgaaggtc cgccaccgga
    23101 agtggtggct cgttttaccg acaacattct gacgcaaaat gcgcgtatgc aggcattggt
    23161 agaaacgtta ctacgccagg caagactgga gaatcgtcag gaagtcgttc tgactgttgt
    23221 tgatgtggcg gcattatttc gccgcgtcag cgaagcgcgc accgtgcagt tggcagaaaa
    23281 aaacatcact ctacatgtta tgcccactga ggttaatgtt gctgctgaac cggcgttact
    23341 ggagcaggcg ctggggaatt tactggataa cgccatcgat tttacccccg agagcggtcg
    23401 cataacgcta agcgccgaag tggatcagga acacgtcgcc cttaaggtgc tggataccgg
    23461 tagtggtatt cctgactacg cgctgtcacg tatttttgaa cgcttttact ctttgccgcg
    23521 tgcaaatggg caaaaaagca gcggtctggg gttggcgttc gtcagtgagg tcgcccgttt
    23581 gtttaacggc gaagtcacgc tgcgcaacgt gcaggaaggt ggcgtgctgg cctcgcttcg
    23641 acttcaccgt cacttcacat agcttcaaat tcttcccaca tagccttcgt atcctgctgc
    23701 cattgcaaag gagaagacta tgttgaaatc ccccctgttc tggaaaatga ccaccctgtt
    23761 tggtgccgta ttgctgttgt tgattccgat aatgctgatt cggcaggtga ttgtcgaacg
    23821 tgccgattac cgtagcgatg tggaagatgc gattcgccaa agtaccagcg ggccgcaaaa
    23881 actcgttggg ccgcttatcg ctattcctgt gaccgagctt tatacggtac aggaagagga
    23941 taaaaccgtg gagcggaaac gaagttttat ccatttttgg ttacctgagt cattgatggt
    24001 tgatggcaat cagaacgtgg aagaacgcaa gatagggatt tataccggtc aggtctggca
    24061 cagtgattta acgctaaaag ccgatttcga tgtttcgcgt cttagcgaac tcgacgcgcc
    24121 aaatatcacc tttggcaagc catttattgt gattagcgtc ggggatgcgc gtggtattgg
    24181 tgtggtgaaa gcgcctgaag ttaacggaac ggcgctgacc attgaacccg gcaccgggtt
    24241 agagcaaggc gggcagggcg tgcatatccc tttacccgaa ggggactggc ggaagcagaa
    24301 cctgcagctg aatatggcac tgaatttaag cggtaccggc gatctttctg tggtgcctgc
    24361 cgggcgtaat agcgaaatga ccttaaccag caactggccg catcccagtt ttttaggtga
    24421 ttttctacca gccaaacggg aagttagcga gtcaggtttt caggcgcaat ggcaaagcag
    24481 ctggtttgct aataatctcg gtgagcgttt tgcttcaggc aatgataccg gctgggaaaa
    24541 cttccccgcg tttagcgtcg cagtgacgac gccagccgat caataccaat taactgaccg
    24601 ggcgactaag tacgctattc tgctgattgc gctgactttt atggcgttct ttgtttttga
    24661 aacgctcacc gcgcaacgtt tacacccaat gcaatattta ctggtggggc tttcattagt
    24721 gatgttttat ttgctcttgc tggcgctttc tgaacatacc ggttttaccg gggcatggat
    24781 aatcgccagt ctgattgggg cgttaatgaa cggtatttat ttgcaggcgg tattgaaagg
    24841 ctggcgcaac agcatgttgt ttaccctcgc gctgttgttg ctggatggtg tgatgtgggg
    24901 actactcaac tctgccgata gcgcgctgtt gttgggaacc agtgtgctgg tggtggcact
    24961 ggccggaatg atgtttgtga cccgtaatat cgactggtat gcgttttcac tgccgaaaat
    25021 gaaagccaat aaagaagtta caacggacga tgaattacgt atctggaaat aaggttgaaa
    25081 aaaaaaacgg cgctaaaaag cgccattttt tttgacggtg gtaacgccga ttaatcttcc
    25141 agatcaccgc agaagcgata accttcaccg tggatggtgg cgatgatttc cggcgtatcc
    25201 ggcgtagatt cgaaatgttt acgaatacgg cggatcgtca cgtctacagt acggtcgtgt
    25261 ggtttcagct cacggccggt cattttcttc agcagttcag cacgggactg aattttgcct
    25321 gggttttcac agaagtgaag catggcgcgg aactcgctgc gcggcagctt gtactgctcg
    25381 ccatcagggc cgatcaacga acggctgttg atgtccagtt cccaaccatt gaacttgtag
    25441 ctttcaacgc tacgacgttc ttcgctgaca gtacccagat tcatggtacg ggacagcagg
    25501 ttgcgtgcac gaatagtcag ttcacgcggg ttgaacggtt tggtgatgta gtcatctgca
    25561 ccgatttcga ggccgagaat tttatcgact tcgttgtcac ggccagtcag gaacatcaac
    25621 gcaacattcg cctgctcgcg cagttcacgc gctaacagaa gaccgttctt acccggcaga
    25681 ttgatatcca tgatcaccag gttgatgtca tattcagaga ggatctgatg catttccgcg
    25741 ccatctgtcg cttcgaaaac atcatagcct tccgcttcga aaatactttt caacgtgttg
    25801 cgtgttacca actcgtcttc aacgataaga atgtgcgggg tctgcatgtt tgctacctaa
    25861 attgccaact aaatcgaaac aggaagtaca aaagtccctg acctgcctga tgcatgctgc
    25921 aaattaacat gatcggcgta acatgactaa agtacgtaat tgcgttcttg atgcactttc
    25981 catcaacgtc aacaacatca ttagcttggt cgtgggtact ttccctcagg acccgacagt
    26041 gtcaaaaacg gctgtcatcc taaccatttt aacagcaaca taacaggcta agaggggccg
    26101 gacacccaat aaaactacgc ttcgttgaca tatatcaagt tcaattgtag cacgttaaca
    26161 gtttgatgaa atcatcgtat ctaaatgcta gctttcgtca cattatttta ataatccaac
    26221 tagttgcatc atacaactaa taaacgtggt gaatccaatt gtcgagattt attttttata
    26281 aaattatcct aagtaaacag aaggatatgt agcatttttt aacaattcaa ccgttagtac
    26341 agtcaggaaa tagtttagcc ttttttaagc taagtaaagg gctttttctg cgacttacgt
    26401 taaggatttg taaattcgca ccgcgtaata agttgacagt gatcaccctg ttcgcggtca
    26461 tttggtcaag aagagtggca atatgcgtat aacgattatt ctggtcgcac ccgccagagc
    26521 agaaaatatt ggggcagcgg cgcgggcaat gaaaacgatg gggtttagcg aactgcggat
    26581 tgtcgatagt caggcacatc tggagccagc cactcgctgg gtcgcacatg gatctggtga
    26641 tattattgat aatattaaag ttttcccgac actggttgaa tcgttacacg atgtcgattt
    26701 cactgtcgcc accactgcgc gcagtcgggc gaaatatcat tactacgcaa cgccagtaga
    26761 actggtgccg ctgttagagg aaaaatcttc atggatgagc catgccgcgc tggtgtttgg
    26821 tcgcgaagat tccgggctga ctaacgaaga gttagcgttg gctgacgttc ttactggtgt
    26881 gccgatggtg gcggattatc cttcgctcaa tctggggcag gcagtgatgg tctattgcta
    26941 tcaattagca acattaatac aacaaccgac gaaaagtgac acaacggcag accaacatca
    27001 actgcaagct ttacgcgaac gagtcatggc attgctgacg actctggcag tggcagatga
    27061 cacaaaactg gtcgactggt tacaacaacg tctggggctt ttagagcagc gagacacggc
    27121 aatgttgcac cgtttgctgc atgatattga aaaaaatatc accaaataaa aaacgcctta
    27181 gtaagtattt ttcagctttt cattctgact gcaatgggca atatgtctct gtgtggatta
    27241 aaaaaagagt ctctgacagc agcttctgaa ctggttacct gccgtgagta aattaaaatt
    27301 ttattgactt aggtcactaa atactttaac caatataggc atagcgcaca gacagataaa
    27361 aattacagag tacacaacat ccatgaaacg cattagcacc accattacca ccaccatcac
    27421 cattaccaca ggtaacggtg cgggctgacg cgtacaggaa acacagaaaa aagcccgcac
    27481 ctgacagtgc gggctttttt ttcgaccaaa ggtaacgagg taacaaccat gcgagtgttg
    27541 aagttcggcg gtacatcagt ggcaaatgca gaacgttttc tgcgggttgc cgatattctg
    27601 gaaagcaatg ccaggcaggg gcaggtggcc accgtcctct ctgcccccgc caaaatcacc
    27661 aaccacctgg tggcgatgat tgaaaaaacc attagcggcc aggatgcttt acccaatatc
    27721 agcgatgccg aacgtatttt tgccgaactt ctgacaggac tcaccgccgc ccagccggga
    27781 ttcccgctgg cgcaactgaa aactttcgtc gaccaggaat ttgcccaaat aaaacatgtc
    27841 ctgcatggca ttagtttgtt ggggcagtgc ccggatagca tcaacgctgc gctgatttgc
    27901 cgtggcgaga aaatgtcgat cgccattatg gccggcgtgt tagaagcgcg tggtcacaac
    27961 gttaccgtta tcgatccggt cgaaaaactg ctggcagtgg ggcattacct cgaatctacc
    28021 gtcgatattg ctgagtccac ccgccgtatt gcggcaagtc gtattccggc tgatcacatg
    28081 gtgctgatgg caggtttcac cgccggtaat gaaaaaggcg aactggtggt gcttggacgc
    28141 aacggttccg actactccgc ggcggtgctg gctgcctgtt tacgcgccga ttgttgcgag
    28201 atttggacgg acgttgacgg ggtctatacc tgcgacccgc gtcaggtgcc cgatgcgagg
    28261 ttgttgaagt cgatgtccta ccaggaagcg atggagcttt cctacttcgg cgctaaagtt
    28321 cttcaccccc gcaccattac ccccatcgcc cagttccaga tcccttgcct gattaaaaat
    28381 accggaaatc ctcaagcacc aggtacgctc attggtgcca gccgtgatga agacgaatta
    28441 ccggtcaagg gcatttccaa tctgaataac atggcaatgt tcagcgtttc cggcccgggg
    28501 atgaaaggaa tggtcggcat ggcggcgcgc gtgtttgcag cgatgtcacg cgcccgtatt
    28561 tccgtggtgc tgattacgca atcatcttcc gaatacagta tcagtttctg cgttccgcaa
    28621 agcgactgtg tgcgagctga acgggcaatg caggaagagt tctacctgga actgaaagaa
    28681 ggcttactgg agccgctggc ggtgacggaa cggctggcca ttatctcggt ggtaggtgat
    28741 ggtatgcgca ccttgcgtgg gatctcggcg aaattctttg ccgcgctggc ccgcgccaat
    28801 atcaacattg tcgccattgc tcagggatct tctgaacgct caatctctgt cgtggtaaat
    28861 aacgatgatg cgaccactgg cgtgcgcgtt actcatcaga tgctgttcaa taccgatcag
    28921 gttatcgaag tatttgtgat tggcgtcggt ggcgttggcg gtgcgctgct ggagcaactg
    28981 aagcgtcaac aaagctggct gaagaataaa catatcgact tacgtgtctg cggcgttgcc
    29041 aactcgaagg ctctgcttac caatgtgcat ggcctaaacc tggaaaactg gcaggaagaa
    29101 ctggcgcaag ccaaagagcc gtttaatctc gggcgcttaa ttcgcctcgt gaaagaatat
    29161 catctgctaa acccggtcat tgttgactgc acctccagcc aggcagtggc ggatcaatat
    29221 gccgacttcc tgcgcgaagg tttccatgtg gtgaccccga acaaaaaggc caacacctcg
    29281 tcgatggatt actaccatca gctgcgttac gcggcggaaa aatcacggcg taaattcctt
    29341 tatgacacca acgtcggtgc ggggttgccg gtcattgaga acttgcaaaa cctgctcaac
    29401 gcgggtgatg aattgatgaa attctctggc attctttctg gttcgctttc tttcatcttc
    29461 ggtaagttag acgaagggat gagcttctcc gaggccacca cgctggcaag agaaatgggc
    29521 tataccgaac cggacccgcg agatgatctt tctggtatgg atgtggcgcg caagctgttg
    29581 attctcgccc gtgaaacagg acgatcactg gaactggcgg atatcgaaat cgaatctgtg
    29641 ctgcccgcag agtttaacgc ggaaggcgat gttgcgactt ttatggcgaa tctgtcacag
    29701 ctcgacgatc tctttgccgc gcgcgtggcg aaggcccgtg atgaaggaaa agttttgcgc
    29761 tatgttggca atattgatga agatggcgtc tgccgcgtga agattgctga agtggatggc
    29821 aacgatccgc tgttcaaagt gaaaaacggc gaaaacgcat tggccttcta tagccactat
    29881 tatcagccac tgccgctggt cctgcgcgga tacggtgcgg gtaatgacgt tacagctgcc
    29941 ggtgtctttg ccgatctgct acgcaccctc tcatggaagt taggagtcta aaatggttaa
    30001 ggtttatgcc ccggcttcca gtgccaatat gagcgtcggg tttgatgtgc tcggggcggc
    30061 ggtgacaccc gttgatggtg cattgctcgg agatgtagtc acggttgagg cggcagagac
    30121 attcagtctc aacaacctcg gacgctttgc cgataagctg ccgtcagaac cacgggaaaa
    30181 tatcgtttat cagtgctggg agcgtttttg ccaggagctt ggcaagcaaa ttccagtggc
    30241 gatgactctg gaaaagaata tgccaatcgg ttcgggctta ggctccagcg cctgttcggt
    30301 ggtcgcggcg ctgatggcga tgaatgaaca ctgtggcaag ccgcttaatg acactcgttt
    30361 gctggctttg atgggcgagc tggaaggacg aatctccggc agcattcatt acgacaacgt
    30421 ggcaccgtgt tttcttggtg gtatgcagtt gatgatcgaa gaaaacgaca tcatcagcca
    30481 gcaagtgcca gggtttgatg agtggttgtg ggtgctggcg tatccgggga ttaaagtctc
    30541 gacggcagaa gccagggcta ttttaccggc gcagtatcgc cgccaggatt gcattgcgca
    30601 cgggcgacat ctggctggct tcattcacgc ctgctattcc cgtcagcctg agcttgccgc
    30661 gaagctgatg aaagatgtta tcgctgaacc ctaccgtgaa cggttactgc ctggcttccg
    30721 gcaggcgcgg caggcggttg cggaaatcgg cgcggtagcg agcggtatct ccggctccgg
    30781 cccgaccttg ttcgctctgt gtgacaagcc ggataccgcc cagcgcgttg ccgactggtt
    30841 gggtaagaac tacctgcaaa atcaggaagg ttttgttcat atttgccggc tggatacggc
    30901 gggcgcacga gtactggaaa actaaatgaa actctacaat ctgaaagatc acaatgagca
    30961 ggtcagcttt gcgcaagccg taacccaggg gttgggcaaa aatcaggggc tgttttttcc
    31021 gcacgacctg ccggaattca gcctgactga aattgatgag atgctgaagc tggattttgt
    31081 cacccgcagt gcgaagatcc tctcggcgtt tattggtgat gaaatcccgc aggaaatcct
    31141 ggaagagcgc gtgcgcgcgg cgtttgcctt cccggctccg gtcgccaatg ttgaaagcga
    31201 tgtcggttgt ctggaattgt tccacgggcc aacgctggca tttaaagatt tcggcggtcg
    31261 ctttatggca caaatgctga cccatattgc gggcgataag ccagtgacca ttctgaccgc
    31321 gacctccggt gataccggag cggcagtggc tcatgctttc tacggtttac cgaatgtgaa
    31381 agtggttatc ctctatccac gaggcaaaat cagtccactg caagaaaaac tgttctgtac
    31441 attgggcggc aatatcgaaa ctgttgccat cgacggcgat ttcgatgcct gtcaggcgct
    31501 ggtgaagcag gcgtttgatg atgaagagct gaaagtggcg ctggggttaa actcagctaa
    31561 ctcgattaac atcagccgtt tgctggcgca gatttgctac tactttgaag cagttgcgca
    31621 gctgccgcag gaagcgcgca accagctggt tgtctcggtg ccaagcggaa acttcggcga
    31681 tttgacggcg ggtctgctgg cgaagtcact cggtctgccg gtgaaacgtt ttattgctgc
    31741 gaccaacgtg aacgataccg tgccacgttt cctgcacgac ggtcagtggt cacccaaagc
    31801 gactcaggcg acgttatcca acgcgatgga cgtgagtcag ccgaacaact ggccgcgtgt
    31861 ggaagagttg ttccgccgca aaatctggca actgaaagag ctgggttatg cagccgtgga
    31921 tgatgaaacc acgcaacaga caatgcgtga gttaaaagaa ctgggctaca cttcggagcc
    31981 gcacgctgcc gtagcgtatc gtgcgctgcg tgaccagttg aatccaggcg aatatggctt
    32041 gttcctcggc accgcgcatc cggcgaaatt taaagagagc gtggaagcga ttctcggtga
    32101 aacgttggat ctgccaaaag agctggcaga acgtgctgat ttacccttgc tttcacataa
    32161 tctgcccgcc gattttgctg cgttgcgtaa attgatgatg aatcatcagt aaaatctatt
    32221 cattatctca atcaggccgg gtttgctttt atgcagcccg gcttttttat gaagaaatta
    32281 tggagaaaaa cgacagggaa aaaggagaaa ttctcaataa atgcggtaac ttagagatta
    32341 ggattgcgga gaataacaac cgccgttctc atcgcgtaat ctccggatat cgacccataa
    32401 cgggcaatga taaaaggagt aacctgtgaa aaagatgcaa tctatcgtac tcgcactttc
    32461 cctggttctg gtcgctccca tggcagcaca ggctgcggaa attacgttag tcccgtcagt
    32521 aaaattacag ataggcgatc gtgataatcg tggctattac tgggatggag gtcactggcg
    32581 cgaccacggc tggtggaaac aacattatga atggcgaggc aatcgctggc acccacacgg
    32641 accgccgcca ccgccgcgtc accataagaa agctcatcat gatcatcacg gcggtcatgg
    32701 tccaggcaaa catcaccgct aaatgacaaa tgccgggtaa caatccggca ttcagcgcct
    32761 gatgcgacgc tggcgcgtct tatcaggcct acgtgaattc tgcaatatat tgaatctgca
    32821 tgcttttgta ggccggataa ggcgttcacg ccgcatccgg cattgactgc aaacttaacg
    32881 ctgctcgtag cgtttaaaca ccagttctcc attgctggag gaagcttcat caaagaagta
    32941 accttcgcta ttaaaaccag tcagttgctc tggtttggtc agccgatttt caataataaa
    33001 acgactcatc agaccgcgtg ctttcttagc gtagaagctg atgatcttaa atttgccgtt
    33061 cttctcatcg aggaacaccg gcttgataat ctcggcattc aatttcttcg gcttcaccga
    33121 tttaaaatac tcatctgacg ccagattaat caccacatta tcgccttgtg ctgcgagcgc
    33181 ctcgttcagc ttgttggtga tgatatctcc ccagaattga tacagatctt tccctcgggc
    33241 attctcaaga cggatcccca tttccagacg ataaggctgc attaaatcga gcgggcgcag
    33301 tacgccatac aagccggaaa gcattcgcaa atgctgttgg gcaaaatcga aattgtcttc
    33361 gctgaaagtt tcggcctgca agccggtgta gacatcacct ttaaacgcca gaatcgcctg
    33421 gcgggcattc tccggcgtga aatctggctg ccagtcatga aagcgagcgg cgttgatacc
    33481 cgccagtttg tcgctgatgc gcatcagcgt gctaatctgc ggaggcgtca gtttccgcgc
    33541 ttcatggatc aactgctggg aattgtctaa cagctccggc agcgtatagc gcgtggtggt
    33601 caacgggctt tggtaatcaa gcgttttcgc aggtgaaata agaatcagca tatccagtcc
    33661 ttgcaggaaa tttatgccga ctttagcaaa aaaagagaat gagttgatcg atagttgtga
    33721 ttactcctgc gaaacatcat cccacgcgtc cggagaaagc tggcggccga tatccggatg
    33781 acgcaacgga tcaaacaccg ggcgcacgcc gagtttacgc tggcgtagat aatcactggc
    33841 aatggtatga accacaggcg agagcagtaa aatggcggtc aaattggtaa tagccatgca
    33901 ggccattatg atatctgcca gttgccacat cagcggaaga cttagcaagg tgccgccgat
    33961 gaccgttgcg aaggtgcaga tccgcaaaca ccagatcgct ttagggttgt tcaggcgtaa
    34021 aaagaagaga ttgttttcgg cataaatgta gttggcaacg atggagctga aggcaaacag
    34081 aataaccacg agggtaacaa actcagcacc ccaggaaccc attagcaccc gcatcgcctt
    34141 ctggataagc tgaatacctt ccagcggcat gtaggttgtg ccgttacccg ccagtaatat
    34201 cagcatggcg cttgccgtac agatgaccag ggtgtcgata aaaatgctaa tcatctggac
    34261 aattccttgc gctgccggat gcggaggcca ggacgccgct gccgcagccg cgtttggcgt
    34321 cgaacccatt cccgcctcat tggaaaacat actgcgctga aaaccgttag taatcgcctg
    34381 gcttaaggta tatcccgccg cgccgcctgc cgcttcctgc cagccaaaag cactctcaaa
    34441 aatagaccaa atgacgtggg gaagttgccc gatatttatt acgcaaatca ccatgctggt
    34501 cagcacccag attatcgcca tcaacgggac aaaaccctgc atgagccggg cgacgccatg
    34561 aagaccgcga gtgattgcca gcagagcaaa gacagcgaga ataatgcctg tcaccagcgg
    34621 gggaaaatca aaagaaaaac tcagggctcg ggcaactgcg tttgcctgaa ctccgctgaa
    34681 aattatgccg taggcgatga gcaaaaagac ggcgaacaga acgcccatcc agcgcatccc
    34741 cagcccgcgc gccatatacc atgccggtcc gccacgaaac tgcccattga cgtcacgttc
    34801 tttataaagt tgtgcaaggg aacattcggc aaacgaggtc gccatgccga taaacgcggc
    34861 aacccacatc caaaagacgg ctccaggtcc accggcggta attgccagcg caacgccggc
    34921 caggttgccg ctacccacgc gcgccgcaag actggtacac aatgactgaa atgaggttaa
    34981 accgcctggc tgtggatgaa tgctattttt aagacttttg ccaaactggc ggatgtagcg
    35041 aaactgcaca aatccggtgc gaaaagtgaa ccaacaacct gcgccgaaga gcaggtaaat
    35101 cattaccgat ccccaaagga cgctgttaat aaaggagaaa aaatctggca tgcatatccc
    35161 tcttattgcc ggtcgcgatg actttcctgt gtaaacgtta ccaattgttt aagaagtata
    35221 tacgctacga ggtacttgat aacttctgcg tagcatacat gaggttttgt ataaaaatgg
    35281 cgggcgatat caacgcagtg tcagaaatcc gaaacagtct cgcctggcga taaccgtctt
    35341 gtcggcggtt gcgctgacgt tgcgtcgtga tatcatcagg gcagaccggt tacatccccc
    35401 taacaagctg tttaaagaga aatactatca tgacggacaa attgacctcc cttcgtcagt
    35461 acaccaccgt agtggccgac actggggaca tcgcggcaat gaagctgtat caaccgcagg
    35521 atgccacaac caacccttct ctcattctta acgcagcgca gattccggaa taccgtaagt
    35581 tgattgatga tgctgtcgcc tgggcgaaac agcagagcaa cgatcgcgcg cagcagatcg
    35641 tggacgcgac cgacaaactg gcagtaaata ttggtctgga aatcctgaaa ctggttccgg
    35701 gccgtatctc aactgaagtt gatgcgcgtc tttcctatga caccgaagcg tcaattgcga
    35761 aagcaaaacg cctgatcaaa ctctacaacg atgctggtat tagcaacgat cgtattctga
    35821 tcaaactggc ttctacctgg cagggtatcc gtgctgcaga acagctggaa aaagaaggca
    35881 tcaactgtaa cctgaccctg ctgttctcct tcgctcaggc tcgtgcttgt gcggaagcag
    35941 gcgtgttcct gatctcgcca tttgttggcc gtattcttga ctggtacaaa gcgaatactg
    36001 ataagaaaga gtacgctccg gcagaagatc cgggcgtggt ttctgtatct gaaatctacc
    36061 agtactacaa agagcacggt tatgaaaccg tggttatggg cgcaagcttc cgtaacatcg
    36121 gcgaaattct ggaactggca ggctgcgacc gtcttaccat cgcacctaca ctgctgaaag
    36181 agctggctga gagtgaaggg gctatcgaac gtaaactgtc ttacaccggc gaagtgaaag
    36241 cgcgtccggc gcgtatcact gagtccgagt tcctgtggca gcacaaccag gatccaatgg
    36301 cagtagataa actggcggaa ggtatccgta agtttgctat tgaccaggaa aaactggaaa
    36361 aaatgatcgg cgatctgctg taatcattct tagcgtgacc gggaagtcgg tcacgctacc
    36421 tcttctgaag cctgtctgtc actcccttcg cagtgtatca ttctgtttaa cgagactgtt
    36481 taaacggaaa aatcttgatg aatactttac gtattggctt agtttccatc tctgatcgcg
    36541 catccagcgg cgtttatcag gataaaggca tccctgcgct ggaagaatgg ctgacatcgg
    36601 cgctaaccac gccgtttgaa ctggaaaccc gcttaatccc cgatgagcag gcgatcatcg
    36661 agcaaacgtt gtgtgagcta gtggatgaaa tgagttgcca tctggtgctc accacgggcg
    36721 gaactggccc ggcgcgtcgt gacgtaacgc ccgatgcgac gctggcagta gcggaccgcg
    36781 agatgcctgg ctttggtgaa cagatgcgcc agataagcct gcattttgta ccaactgcga
    36841 tcctttcgcg tcaggttggt gtgattcgca aacaggcgct gatccttaac ttacccggtc
    36901 agccgaagtc tattaaagag acgctggaag gtgtgaagga cgctgcgggt aacgttgtgg
    36961 tacacggtat ttttgccagc gtaccgtact gcattcagtt gctggaaggg ccatacgttg
    37021 aaacggcacc agaagtggtt gctgcattca gaccgaagag tgcaagacgc gacgttagcg
    37081 aataaaaaaa tccccccgag cggggggatc tcaaaacaat tagtgggatt caccaatcgg
    37141 cagaacggtg cgaccaaact gctcgttcag tacttcaccc atcgccagat agattgcgct
    37201 ggcaccgcag atcagaccaa tccagccggc aaagtggatg attgcggcgt taccggcaat
    37261 gttaccgatc gccagcaggg caaacagcac ggtcaggcta aagaaaacga attgcagaac
    37321 gcgtgcgcct ttcagcgtgc cgaagaacat aaacagcgta aatacgcccc acagacccag
    37381 gtagacacca aggaactgtg catttggcgc atcggtcaga cccagtttcg gcatcagcag
    37441 aatcgcaacc agcgtcagcc agaaagaacc gtaagaggtg aatgcggtta aaccgaaagt
    37501 gttgcctttt ttgtactcca gcagaccggc aaaaatttgc gcgatgccgc cgtagaaaat
    37561 gcccatggca agaataatac cgtccagagc gaaataaccc acgttgtgca ggttaagcag
    37621 aatggtggtc atgccgaagc ccatcaggcc cagcggtgcc ggattagcca acttagtgtt
    37681 gcccataatt cctcaaaaat catcatcgaa tgaatggtga aataatttcc ctgaataact
    37741 gtagtgtttt cagggcgcgg cataataatc agccagtggg gcagtgtcta cgatcttttg
    37801 aggggaaaat gaaaattttc cccggtttac ggtgtcagac ctgagtggcg ctaaccatcc
    37861 ggcgcaggca ggcgatttgc agtacggctg gaattgtcac gcgataggca ctgccgctga
    37921 ccgctttaac cccatttaat gctgcgccca cagggcctcc cagacccgcg ccgcgcagca
    37981 aaccatgccc aagcacgctc attgctgcgt gggtgcgtaa aatgcgggtc agttggctgg
    38041 aaagcaaatg cgacacgcct tttgccaata atttgtcttt catcagcagc ggcagcagct
    38101 cttccagctc attcaccctg gcatcgaccg cgtgcagaaa ctcctgctta tgttcctcgt
    38161 ccatattctt ccaggtgtta cgcagaaatt gttccagtaa ctgttgctca atctcaaacg
    38221 tagacatctc tttgtcggct ttcagcttca atcgttttga aacatcgagc aaaatggccc
    38281 gatacaattt accgtgtccg cgcagtttgt tggcgatact atcgccacca aaatgctgta
    38341 attctccggc aatcagctgc cagttgcggc gatgttgctc gggatgccct tccatcgatt
    38401 taaacagttc gttgcgcatc agtacgctgg agaggcgagt tttgcctttt tcattatggg
    38461 tgagcaatcg ggcgaaattt gccaactgtt cctcactaca atgctgaaga aaatccagat
    38521 ctgaatcatt caggtaatta acattcattt tttgtggctt ctatattctg gcgttagtcg
    38581 tcgccgataa ttttcagcgt ggccatatcc gatgagttca ccgtatgacc cgaaaaggtg
    38641 atttttgaga cgcagcgttt attgtcgtta tcgctgttaa tgttgatcca gtcagtggtt
    38701 tgcccttctt ttatttctga aggaatattc aggctctgac tggcgctacg ggcggctttg
    38761 aaataaaccg atgcaccgct taactgtaaa tcgccatggt cggcagagag ttgtatgcgt
    38821 ttcacaatgc gacaaacagg aagtttcagc gccagatcgt tggtttcgtt acgcggcatt
    38881 gcaatggcgc cgaggagttt atggtcgttt gcctgcgccg tgcagcacag catcaggcta
    38941 atcgccaggc tggcggaaat cgtaaaaacg gatttcataa ggattctctt agtgggaaga
    39001 ggtaggggga tgaataccca ctagtttact gctgataaag agaagattca ggcacgtaat
    39061 cttttctttt tattacaatt ttttgatgaa tgccttggct gcgattcatt ctttatatga
    39121 ataaaattgc tgtcaatttt acgtcttgtc ctgccatatc gcgaaatttc tgcgcaaaag
    39181 cacaaaaaat ttttgcatct cccccttgat gacgtggttt acgaccccat ttagtagtca
    39241 accgcagtga gtgagtctgc aaaaaaatga aattgggcag ttgaaaccag acgtttcgcc
    39301 cctattacag actcacaacc acatgatgac cgaatatata gtggagacgt ttagatgggt
    39361 aaaataattg gtatcgacct gggtactacc aactcttgtg tagcgattat ggatggcacc
    39421 actcctcgcg tgctggagaa cgccgaaggc gatcgcacca cgccttctat cattgcctat
    39481 acccaggatg gtgaaactct agttggtcag ccggctaaac gtcaggcagt gacgaacccg
    39541 caaaacaccc tgtttgcgat taaacgcctg attggccgcc gcttccagga cgaagaagta
    39601 cagcgtgatg tttccatcat gccgttcaaa attattgctg ctgataacgg cgacgcatgg
    39661 gtcgaagtta aaggccagaa aatggcaccg ccgcagattt ctgctgaagt gctgaaaaaa
    39721 atgaagaaaa ccgctgaaga ttacctgggt gaaccggtaa ctgaagctgt tatcaccgta
    39781 ccggcatact ttaacgatgc tcagcgtcag gcaaccaaag acgcaggccg tatcgctggt
    39841 ctggaagtaa aacgtatcat caacgaaccg accgcagctg cgctggctta cggtctggac
    39901 aaaggtactg gcaaccgtac tatcgcggtt tatgacctgg gtggtggtac tttcgatatt
    39961 tctattatcg aaatcgacga agttgacggc gaaaaaacct tcgaagttct ggctaccaac
    40021 ggtgataccc acctgggtgg tgaagacttc gacagccgtc tgatcaacta cctggttgaa
    40081 gaattcaaga aagatcaggg cattgacctg cgcaacgatc cgctggcaat gcagcgcctg
    40141 aaagaagcgg cagaaaaagc gaaaatcgaa ctgtcttccg ctcagcagac cgacgttaac
    40201 ctgccgtaca tcactgcaga tgcgaccggt ccgaaacaca tgaacatcaa agtgactcgt
    40261 gcgaaactgg aaagcctggt tgaagatctg gtaaaccgtt ccattgagcc gctgaaagtt
    40321 gcactgcagg acgctggcct gtccgtatct gatatcgacg acgttatcct cgttggtggt
    40381 cagactcgta tgccaatggt tcagaagaaa gttgctgagt tctttggtaa agagccgcgt
    40441 aaagacgtta acccggacga agctgtagca atcggtgctg ctgttcaggg tggtgttctg
    40501 actggtgacg tgaaagacgt actgctgctg gacgttaccc cgctgtctct gggtatcgaa
    40561 accatgggcg gtgtgatgac gacgctgatc gcgaaaaaca ccactatccc gaccaagcac
    40621 agccaggtgt tctctaccgc tgaagacaac cagtctgcgg taaccatcca tgtgctgcag
    40681 ggtgaacgta aacgtgcggc tgataacaaa tctctgggtc agttcaacct agatggtatc
    40741 aacccggcac cgcgcggcat gccgcagatc gaagttacct tcgatatcga tgctgacggt
    40801 atcctgcacg tttccgcgaa agataaaaac agcggtaaag agcagaagat caccatcaag
    40861 gcttcttctg gtctgaacga agatgaaatc cagaaaatgg tacgcgacgc agaagctaac
    40921 gccgaagctg accgtaagtt tgaagagctg gtacagactc gcaaccaggg cgaccatctg
    40981 ctgcacagca cccgtaagca ggttgaagaa gcaggcgaca aactgccggc tgacgacaaa
    41041 actgctatcg agtctgcgct gactgcactg gaaactgctc tgaaaggtga agacaaagcc
    41101 gctatcgaag cgaaaatgca ggaactggca caggtttccc agaaactgat ggaaatcgcc
    41161 cagcagcaac atgcccagca gcagactgcc ggtgctgatg cttctgcaaa caacgcgaaa
    41221 gatgacgatg ttgtcgacgc tgaatttgaa gaagtcaaag acaaaaaata atcgccctat
    41281 aaacgggtaa ttatactgac acgggcgaag gggaatttcc tctccgcccg tgcattcatc
    41341 taggggcaat ttaaaaaaga tggctaagca agattattac gagattttag gcgtttccaa
    41401 aacagcggaa gagcgtgaaa tcagaaaggc ctacaaacgc ctggccatga aataccaccc
    41461 ggaccgtaac cagggtgaca aagaggccga ggcgaaattt aaagagatca aggaagctta
    41521 tgaagttctg accgactcgc aaaaacgtgc ggcatacgat cagtatggtc atgctgcgtt
    41581 tgagcaaggt ggcatgggcg gcggcggttt tggcggcggc gcagacttca gcgatatttt
    41641 tggtgacgtt ttcggcgata tttttggcgg cggacgtggt cgtcaacgtg cggcgcgcgg
    41701 tgctgattta cgctataaca tggagctcac cctcgaagaa gctgtacgtg gcgtgaccaa
    41761 agagatccgc attccgactc tggaagagtg tgacgtttgc cacggtagcg gtgcaaaacc
    41821 aggtacacag ccgcagacct gtccgacctg tcatggttct ggtcaggtgc agatgcgcca
    41881 gggtttcttt gccgtgcagc agacctgtcc acactgtcag ggccgcggta cgctgatcaa
    41941 agatccgtgc aacaaatgtc atggtcatgg tcgtgttgag cgcagcaaaa cgctgtccgt
    42001 taaaatcccg gcaggggtgg acactggaga ccgcatccgt cttgcgggcg aaggtgaagc
    42061 gggcgagcat ggcgcaccgg caggcgatct gtacgttcag gttcaggtta aacagcaccc
    42121 gattttcgag cgtgaaggca ataacctgta ttgcgaagtc ccgatcaact tcgctatggc
    42181 ggcgctgggt ggcgaaatcg aagtaccgac ccttgatggt cgcgtcaaac tgaaagtgcc
    42241 tggcgaaacc cagaccggta agctattccg tatgcgcggt aaaggcgtca agtctgtccg
    42301 cggtggcgca cagggtgatt tgctgtgccg cgttgtcgtc gaaacaccgg taggcctgaa
    42361 cgagaagcag aaacagctgc tgcaagagct gcaagaaagc ttcggtggcc caaccggcga
    42421 gcacaacagc ccgcgctcaa agagcttctt tgatggtgtg aagaagtttt tcgacgacct
    42481 gactcgctaa cctccccaaa agcctgcccg tgggcaggct tgggtaaaaa tagggtgcgt
    42541 tgaagatatg cgagcacctg taaagtggcg ggaatcactc cccgccgttg ctcttactcg
    42601 gattcgtaag ccgtgaaaac agcaacctcc gtctggccag ttcggatgtg aacctcacag
    42661 aggtcttttc ttgttaccag cgccgccact acggcggtga tacagatgac gatcagggcg
    42721 acaatcatcg ccttatgctg cttcattgct ctcttctcct tgaccttacg gtcagtaaga
    42781 ggcactctac atgtgttctg catatagggg gcctcggg
//
LOCUS       DAPOAV010000033        42140 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.033, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000033 DAPOAV010000000
VERSION     DAPOAV010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 42140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42140
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.033"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(9..1658)
                     /gene="actP"
                     /locus_tag="RN951_002047"
     CDS             complement(9..1658)
                     /gene="actP"
                     /locus_tag="RN951_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation/acetate symporter ActP"
                     /protein_id="HDX2527048.1"
                     /translation="MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVV
                     FTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYD
                     GLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
                     YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFG
                     ASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTA
                     GLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPEYKDAAG
                     HLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVF
                     KKGATEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLS
                     MYWSKLTTRGAMMGGWLGLITAVVLMILGPTIWVQILGHEKAIFPYEYPALFSITVAF
                     LGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH"
     gene            complement(1655..1969)
                     /locus_tag="RN951_002048"
     CDS             complement(1655..1969)
                     /locus_tag="RN951_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF485 domain-containing protein"
                     /protein_id="HDX2527049.1"
                     /translation="MNGTIYQRIEDNAHFRELVEKRQRFATILSIIMLAVYIGFILLI
                     AFAPGWLGTPLNPNTSVTRGIPIGVGVIVISFVLTGIYIWRANGEFDRLNNEVLHEVQ
                     AS"
     gene            complement(2169..4127)
                     /gene="acs"
                     /locus_tag="RN951_002049"
     CDS             complement(2169..4127)
                     /gene="acs"
                     /locus_tag="RN951_002049"
                     /EC_number="6.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase"
                     /protein_id="HDX2527050.1"
                     /translation="MSQIHKHTIPANIADRCLINPQQYEAMYQQSINVPDTFWGEQGK
                     ILDWIKPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDA
                     SQSKHISYKELHRDVCRFANTLLELGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHS
                     VIFGGFSPEAVAGRIIDSNSRLVITSDEGVRAGRSIPLKKNVDDALKNPNVTSVEHVV
                     VLKRTGGKIDWQEGRDLWWHDLVEQASDQHQAEEMNAEDPLFILYTSGSTGKPKGVLH
                     TTGGYLVYAALTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVP
                     NWPTPARMAQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINP
                     EAWEWYWKKIGNEKCPVVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALVD
                     NEGNPLEGATEGSLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDG
                     YYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHNIKGQAIYAYVTLN
                     HGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTS
                     NLGDTSTLADPGVVEKLLEEKQAIAMPS"
     gene            4520..5956
                     /gene="nrfA"
                     /locus_tag="RN951_002050"
     CDS             4520..5956
                     /gene="nrfA"
                     /locus_tag="RN951_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-forming nitrite reductase cytochrome
                     c552 subunit"
                     /protein_id="HDX2527051.1"
                     /translation="MTRIKINARRIFSLLIPFFFFTSVHAEQTAAPAKPVTVEAKNET
                     FAPQHPDQYLSWKATSEQSERVDALAEDPRLVILWAGYPFSRDYNKPRGHAFAVTDVR
                     ETLRTGAPKNAEDGPLPMACWSCKSPDVARLIQKDGEDGYFHGKWARGGPEIVNNLGC
                     ADCHNTASPEFAKGKPELTLSRPYAARAMEAIGKPFEKAGRFDQQSMVCGQCHVEYYF
                     DGKNKAVKFPWDDGMKVENMEQYYDKIAFSDWTNSLSKTPMLKAQHPEYETWTAGIHG
                     KNNVTCIDCHMPKVQNAEGKLYTDHKIGNPFDNFAQTCANCHTQDKAALQKVVAERKQ
                     SINDLKIKVEDQLVHAHFEAKAALDAGATEAEMKPIQDDIRHAQWRWDLAIASHGIHM
                     HAPEEGLRMLGTAMDKAADARTKLARLLATKGITHEIQIPDISTKEKAQQAIGLNMEQ
                     IKAEKQDFIKTVIPQWEEQARKNGLLSQ"
     gene            6001..6567
                     /gene="nrfB"
                     /locus_tag="RN951_002051"
     CDS             6001..6567
                     /gene="nrfB"
                     /locus_tag="RN951_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418495.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase pentaheme
                     subunit"
                     /protein_id="HDX2527052.1"
                     /translation="MSVLRSLLTAGVLASGLLWSLNGITATPAAQASDDRYEVTQQRN
                     PDAACLDCHKPDTEGMHGKHASVINPNNKLPVTCTNCHGQPSPQHREGVKDVMRFNEP
                     MYKVGEQNSVCMSCHLPEQLQKAFWPHDVHVTKVACASCHSLHPQQDTMQTLSDKGRI
                     KICVDCHSDQRTNPNFNPASVPLLKEQP"
     gene            6564..7235
                     /gene="nrfC"
                     /locus_tag="RN951_002052"
     CDS             6564..7235
                     /gene="nrfC"
                     /locus_tag="RN951_002052"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase Fe-S protein"
                     /protein_id="HDX2527053.1"
                     /translation="MTWSRRQFLTGVGVLAAVSGTAGRVVAKTLNINGVRYGMVHDES
                     LCIGCTACMDACREVNKVPEGVSRLTIIRSEPQGEFPDVKYRFFRKSCQHCDHAPCVD
                     VCPTGASFRDAASGIVDVNPDLCVGCQYCIAACPYRVRFIHPVTKTADKCDFCRKTNL
                     QAGKLPACVEACPTKALTFGNLDDPNSEISQLLRQKPTYRYKLALGTKPKLYRVPFKY
                     GEVSQ"
     gene            7232..8188
                     /gene="nrfD"
                     /locus_tag="RN951_002053"
     CDS             7232..8188
                     /gene="nrfD"
                     /locus_tag="RN951_002053"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase subunit NrfD"
                     /protein_id="HDX2527054.1"
                     /translation="MTQTSAFHFESLVWDWPIAIYLFLIGISAGLVTLAVLLRRFYPQ
                     AGGADSTLLRTTLIVGPGAVILGLLILVFHLTRPWTFWKLMFHYSFTSVMSMGVMLFQ
                     LYMVVLVLWLAKIFEHDLLALQQRWLPKLGIVQKVLSLLTPVHRGLETLMLVLAVLLG
                     AYTGFLLSALKSYPFLNNPILPVLFLFSGISSGAAVALIAMAIRQRSNPHSTEAQFVH
                     RMEIPVVWGEIFLLVAFFVGLALGDDGKVRALVAALGGGFWTWWFWLGVAGLGLIVPM
                     LLKPWVNRSSGIPAVLAACGASLVGVLMLRFFILYAGQLTVA"
     gene            8208..9926
                     /locus_tag="RN951_002054"
     CDS             8208..9926
                     /locus_tag="RN951_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014640253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase CcmF/NrfE family subunit"
                     /protein_id="HDX2527055.1"
                     /translation="MDVFLPEVGFLALLLSLGVNVLTPLTAFAGVRLRWPAMMRLTCI
                     GILAQFALLLLAFGVLTYCFLISDFSVIYVAQHSYSLLSWELKLAAVWGGHEGSLLLW
                     VLLLSAWSALFAWHYRQQTDPLFPLTLAVLSLMLAALLLFVVLWSDPFVRIFPPAIEG
                     RDLNPMLQHPGLIFHPPLLYLGYGGLMVAASVALASLLRGEFDGACARICWRWALPGW
                     SALTAGIILGSWWAYCELGWGGWWFWDPVENASLLPWLSATALLHSLSLTRQRGIFCH
                     WSLLLAIVTLMLSLLGTLIVRSGILVSVHAFALDNVRAVPLFSLFALISLASLALYGW
                     RARDGGPAVHFSGLSREMLILATLLLFCAVLLIVLVGTLYPMIYGLLGWGRLSVGAPY
                     FNRATLPFGLLMLVVIVLATFVSGKRVQLPALVAHAGVLLFAAGVVVSSVSRQEISLN
                     LQPGQQVTLAGYTFRFECLDLQAKGNYTSEKAIVALFDHQQRIGELTPERRFYEARRQ
                     QMMEPSIRWNGIHDWYAVMGEKTGPDRYAFRLYVQSGVRWIWGGGLLMIAGALLSGWR
                     GKKRDE"
     gene            9919..10302
                     /gene="nrfF"
                     /locus_tag="RN951_002055"
     CDS             9919..10302
                     /gene="nrfF"
                     /locus_tag="RN951_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfF"
                     /protein_id="HDX2527056.1"
                     /translation="MNKGLLTLLLLFTCFAHAQVVDTWQFANPQQQQQALNIASQLRC
                     PQCQNQNLLESNAPVAVSMRHQVYSMVAEGKNEVEIIGWMTERYGDFVRYNPPLTGQT
                     LVLWALPVVLLLLMALILWRVRAKR"
     gene            10299..10895
                     /gene="nrfG"
                     /locus_tag="RN951_002056"
     CDS             10299..10895
                     /gene="nrfG"
                     /locus_tag="RN951_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfG"
                     /protein_id="HDX2527057.1"
                     /translation="MKQPKIPVKMLTTLTILMVFLCVGSYLLSPKWQAVRAEYQRQRD
                     PLHQFASQQTPEAQLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQL
                     RGENAELYAALATVLYYQASQHMTAQTRAMIDKALALDSNEITALMLLASDAFMQANY
                     AQAIELWQKVMDLNSPRVNRTQLVESINMAKLLQRRLD"
     gene            11237..12550
                     /gene="gltP"
                     /locus_tag="RN951_002057"
     CDS             11237..12550
                     /gene="gltP"
                     /locus_tag="RN951_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate:proton symporter GltP"
                     /protein_id="HDX2527058.1"
                     /translation="MKNIKFSLAWQILFAMVLGILLGSYLHYHSDSRDWLVVNLLSPA
                     GDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRIGAKTIIYFEVITTVAIILGITL
                     ANVFQPGAGVDMSQLATVDISKYQSTTEAVQSSSHGIMGTILSLVPTNIVASMAKGEM
                     LPIIFFSVLFGLGLSSLPATHREPLVTVFRSISETMFKVTHMVMRYAPVGVFALIAVT
                     VANFGFSSLWPLAKLVLLVHFAILFFALVVLGIVARLCGLSVWILIRILKDELILAYS
                     TASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGID
                     LSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMA
                     RTALNVVGNALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTADQ"
     gene            complement(12629..13318)
                     /locus_tag="RN951_002058"
     CDS             complement(12629..13318)
                     /locus_tag="RN951_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDX2527059.1"
                     /translation="MKKIIALMLFLTFFAHANDSEPGSQYLKAAEAGDRRAQYFLADS
                     WFSSGDLSKAEYWAQKAADSGDADACALLAQIKITNPVSLDYPQAKVLAEKAAQAGSK
                     EGEVTLAHILVNTQAGKPDYPKAISLLENASEDLENDSAVDAQMLLGLIYANGVGIKA
                     DDDKATWYFKRSSAISRTGYSEYWAGMMFLNGEEGFIEKNKQKALHWLNLSCMEGFDT
                     GCEEFEKLTNG"
     gene            complement(13412..15559)
                     /gene="fdhF"
                     /locus_tag="RN951_002059"
     CDS             complement(13412..15559)
                     /gene="fdhF"
                     /locus_tag="RN951_002059"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(15140..15142),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HDX2527060.1"
                     /translation="MKKVVTVCPYCASGCKINLVVDNGKIVRAEAAQGKTNQGTLCLK
                     GYYGWDFINDTQILTPRLKTPMIRRQRGGKLEPVSWDEALNYVAERLSAIKEKYGPDA
                     IQTTGSSRGTGNETNYVMQKFARAVIGTNNVDCCARVUHGPSVAGLHQSVGNGAMSNA
                     INEIDNTDLVFVFGYNPADSHPIVANHVINAKRNGAKIIVCDPRKIETARIADMHIAL
                     KNGSNIALLNAMGHVIIEENLYDKAFVASRTEGFEEYRKIVEGYTPESVEDITGVSAS
                     EIRQAARMYAQAKSAAILWGMGVTQFYQGVETVRSLTSLAMLTGNLGKPHAGVNPVRG
                     QNNVQGACDMGALPDTYPGYQYVKDPANREKFAKAWGVESLPAHTGYRISELPHRAAH
                     GEVRAAYIMGEDPLQTDAELSAVRKAFEDLELVIVQDIFMTKTASAADVILPSTSWGE
                     HEGVFTAADRGFQRFFKAVEPKWDLKTDWQIISEIATRMGYPMHYNNTQEIWDELRHL
                     CPDFYGATYEKMGELGFIQWPCRDTSDADQGTSYLFKEKFDTPNGLAQFFTCDWVAPI
                     DKLTDEYPMVLSTVREVGHYSCRSMTGNCAALAALADEPGYAQINTEDAKRLGIEDEA
                     LVWVHSRKGKIITRAQVSDRPNKGAIYMTYQWWIGACNELVTENLSPITKTPEYKYCA
                     VRVEPIADQRAAEQYVIDEYNKLKTRLREAALA"
     gene            complement(15757..17223)
                     /gene="mdtP"
                     /locus_tag="RN951_002060"
     CDS             complement(15757..17223)
                     /gene="mdtP"
                     /locus_tag="RN951_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter outer membrane
                     subunit MdtP"
                     /protein_id="HDX2527061.1"
                     /translation="MINRQLSRLLLCSILGSTTLISGCALVRKDSAPHQQLKPEQIKL
                     ADDIHLASSGWPQAQWWKQLNDPQLDALIQRTLSGSHTLAEAKLREEKAQSQADLLDA
                     GSQLQVAALGMLNRQRVSANGFLSPYSMDAPALGMDGPYYTEATVGLFAGLDLDLWGV
                     HRSAVAAAIGAHNAALAETAAVELSLATGVAQLYYSMQASYQMLDLLEQTHDVIDYAV
                     KAHQSKVAHGLEAQVPFHGARAQILAVDKQIVAVKGQITETRESLRALIGAGASDMPE
                     IRPVALPQVQTGIPATLSYELLARRPDLQAMRWYVQASLDQVDSARALFYPSFDIKAF
                     FGLDSIHLHTLFKKTSRQFNFIPGLKLPLFDGGRLNANLEGTRAASNMMIERYNQSVL
                     NAVRDVAVNGTRLQTLNDEREMQAERVEATRFTQRAAEAAYQRGLTSRLQATEARLPV
                     LAEEMSLLMLDSRRVIQSIQLMKSLGGGYQAGPVVEKK"
     gene            complement(17220..19271)
                     /gene="mdtO"
                     /locus_tag="RN951_002061"
     CDS             complement(17220..19271)
                     /gene="mdtO"
                     /locus_tag="RN951_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418505.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter permease subunit
                     MdtO"
                     /protein_id="HDX2527062.1"
                     /translation="MSALNSLPLPVVRLLAFFHEELSERRPGRVPQTVQLWVGCLLVI
                     LISMTFEIPFVALSLAVLFYGIQSNAFYTKFVAILFVVATVLEIGSLFLIYKWSYGEP
                     LIRLIIAGPILMGCMFLMRTHRLGLVFFAVAIVAIYGQTFPAMLDYPEVVVRLTLWCI
                     VVGLYPTLLMTLIGVLWFPSRAISQMHQALNDRLDDAISHLTDSLVPLPETRIEREAL
                     ALQKLNVFCLADDANWRTQNAWWQSCVATVTYIYSTLNRYDPTSFADSQAIIEFRQKL
                     ASEINKLQHAVAEGQCWQSDWRISESEAMAARECNLENICQTLLQLGQMDPNTPPTPA
                     AKPPSMAADAFTNPDYMRYAVKTLLACLICYTFYSGVDWEGIHTCMLTCVIVANPNVG
                     SSYQKMVLRFGGAFCGAILALLFTLLVMPWLDNIVELLFVLAPIFLLGAWIATSSERS
                     SYIGTQMVVTFALATLENVFGPVYDLVEIRDRALGIIIGTVVSAVIYTFVWPESEART
                     LPQKLAGTLGMLSKVMRIPRQQEVTALRTYLQIRIGLHAAFNACEEMCQRVALERQLD
                     SEERALLIERSQTVIRQGRDLLHAWDATWNSAQALDNALQPDRAGQFADALEKYAAGL
                     ATALSRSPQITLEETPASQAILPTLLKQEQHVCQLFARLPDWTAPALTPATEQAQGAT
                     Q"
     gene            complement(19271..20302)
                     /gene="mdtN"
                     /locus_tag="RN951_002062"
     CDS             complement(19271..20302)
                     /gene="mdtN"
                     /locus_tag="RN951_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter periplasmic adaptor
                     subunit MdtN"
                     /protein_id="HDX2527063.1"
                     /translation="MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYA
                     SADTIDVVPEVSGRIVELAVTDNQAVKQGDLLFRIDPRPYEANLAKAEASLAALDKQI
                     MLTQRSVDAQQFGADSVNATVEKARAAAKQATDTLRRTEPLLKEGFVSAEDVDRARTA
                     QRAAEADLNAVLLQAQSAASAVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGR
                     VISLKTSVGQFASAMRPIFTLIDTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKT
                     FEGKVDSIGYGVLPDDGGLVLGGLPKVSRSINWVRVAQRFPVKIMVDKPDPEMFRIGA
                     SAVANLEPQ"
     gene            complement(20321..20596)
                     /locus_tag="RN951_002063"
     CDS             complement(20321..20596)
                     /locus_tag="RN951_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527064.1"
                     /translation="MPTVLSRMAMQLKKTAWIIPVFMVSGCSLSPAIPVIGAYYPSWF
                     FCAIASLILTLITRRVIQRANINLAFVGIIYTALFALYAMLFWLAFF"
     gene            complement(20805..22790)
                     /gene="yjcS"
                     /locus_tag="RN951_002064"
     CDS             complement(20805..22790)
                     /gene="yjcS"
                     /locus_tag="RN951_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl sulfatase YjcS"
                     /protein_id="HDX2527065.1"
                     /translation="MNNSRLFRLSRIVIALTAASGMMVNTANAKEEAKAATQYTQQVN
                     QNYAKSLPFSDRQDFDDAQRGFIAPLLDEGILRDANGKVYYRADDYKFDINAAAPETV
                     NPSLWRQSQINGISGLFKVTDKMYQVRGQDISNITFVEGEKGIIVIDPLVTPPAAKAA
                     LDLYFQHRPQKPIVAVIYTHSHTDHYGGVKGIISEADVKSGKVQVIAPAGFMDEAISE
                     NVLAGNIMSRRALYSYGLLLPHNAQGNVGNGLGVTLATGDPSIIAPTKTIVRTGEKMI
                     IDGLEFDFLMTPGSEAPAEMHFYIPALKALCTAENATHTLHNFYTLRGAKTRDTSKWT
                     EYLNETLDMWGNDAEVLFMPHTWPVWGNKHINDYIGKYRDTIKYIHDQTLHLANQGYT
                     MNEIGDMIKLPPALANNWASRGYYGSVSHNARAVYNFYLGYYDGNPANLHPYGQVEMG
                     KRYVQALGGSARVINLAQEANKQGDYRWSAELLKQVIAANPGDQVAKNLQANNFEQLG
                     YQAESATWRGFYLTGAKELREGVHKFSHGTTGSPDTIRGMSVEMLFDFMAVRLDSAKA
                     AGKNISLNFNMSNGDNLNLTLNDSVLNYRKTLQPQADASFYISREDLHAVLTGQAKMA
                     DLVKAKKAKIIGNGAKLEEIIACLDNFDLWVNIVTPN"
     gene            complement(23063..23992)
                     /gene="alsK"
                     /locus_tag="RN951_002065"
     CDS             complement(23063..23992)
                     /gene="alsK"
                     /locus_tag="RN951_002065"
                     /EC_number="2.7.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allose kinase"
                     /protein_id="HDX2527066.1"
                     /translation="MQKQHNVVAGVDMGATHIRFCLRTAEGETLHCEKKRTAEVIAPG
                     LVSGIGEMIDEQLRRFNARCHGLVMGFPALVSKDKRTIISTPNLPLTAADLYDLADKL
                     ENTLNCPVEFSRDVNLQLSWDVVENRLTQQLVLAAYLGTGMGFAVWMNGAPWTGAHGV
                     AGELGHIPLGDMTQHCACGNPGCLETNCSGMALRRWYEQQPRNYPLRDLFVHAENAPF
                     VQSLLENAARAIATSINLFDPDAVILGGGVMDMPAFPRETLVAMTQKYLRRPLPHQVV
                     RFIAASSSDFNGAQGAAILAHQRFLPQFCAKAP"
     gene            complement(23976..24671)
                     /gene="alsE"
                     /locus_tag="RN951_002066"
     CDS             complement(23976..24671)
                     /gene="alsE"
                     /locus_tag="RN951_002066"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allulose-6-phosphate 3-epimerase"
                     /protein_id="HDX2527067.1"
                     /translation="MKISPSLMCMDLLKFKEQIEFIDSHADYFHIDIMDGHFVPNLTL
                     SPFFVSQVKKLATKPLDCHLMVTRPQDYIAQLARAGADFITLHPETINGQAFRLIDEI
                     RRHDMKVGLILNPETPVEAMKYYIHKADKITVMTVDPGFAGQPFIPEMLDKLAELKAW
                     REREGLEYEIEVDGSCNQATYEKLMAAGADVFIVGTSGLFNHAENIDEAWRIMTAQIL
                     AAKSEVQPHAKTA"
     gene            complement(24682..25662)
                     /gene="alsC"
                     /locus_tag="RN951_002067"
     CDS             complement(24682..25662)
                     /gene="alsC"
                     /locus_tag="RN951_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose ABC transporter permease"
                     /protein_id="HDX2527068.1"
                     /translation="MGFTTRVKSEASEKKPFNFALFWDKYGTFFILAIIVAIFGSLSP
                     EYFLTTNNITQIFVQSSVTVLIGMGEFFAILVAGIDLSVGAILALSGMVTAKLMLAGV
                     DPFLAAMIGGVLVGGALGAINGCLVNWTGLHPFIITLGTNAIFRGITLVISDANSVYG
                     FSFDFVNFFAASVIGIPVPVIFSLIVALILWFLTTRMRLGRNIYALGGNKNSAFYSGI
                     DVKFHILVVFIISGVCAGLAGVVSTARLGAAEPLAGMGFETYAIASAIIGGTSFFGGK
                     GRIFSVVIGGLIIGTINNGLNILQVQTYYQLVVMGGLIIAAVALDRLISK"
     gene            complement(25641..27173)
                     /gene="alsA"
                     /locus_tag="RN951_002068"
     CDS             complement(25641..27173)
                     /gene="alsA"
                     /locus_tag="RN951_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose ABC transporter ATP-binding protein
                     AlsA"
                     /protein_id="HDX2527069.1"
                     /translation="MATPYISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGK
                     STLMKVLSGIHEPTKGTITINNISYNKLDHKLAAQLGIGIIYQELSVIDELTVLENLY
                     IGRHLTKKICGVNIIDWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTL
                     MLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVM
                     KDGSSVCSGIVSDVSNDDIVRLMVGRELQNRFNAMKENVSNLAHETVFEVRNVTSRDR
                     KKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLD
                     AVKKGMAYITESRRDNGFFPNFSIAQNMAISRSLKDGGYKGAMGLFHEVDEQRTAENQ
                     RELLALKCHSVNQNITELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVDAKAEIYK
                     VMRQLADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQILTNRDDMSEEEIMAWALP
                     QE"
     gene            complement(27300..28235)
                     /gene="alsB"
                     /locus_tag="RN951_002069"
     CDS             complement(27300..28235)
                     /gene="alsB"
                     /locus_tag="RN951_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose transporter substrate-binding protein"
                     /protein_id="HDX2527070.1"
                     /translation="MNKYLKYFSGTLVGLMLSTSAFAAAEYAVVLKTLSNPFWVDMKK
                     GIEDEAKTLGVSVDIFASPSEGDFQSQLQLFEDLSNKNYKGIAFAPLSSVNLVMPVAR
                     AWKKGIYLVNLDEKIDMDNLKKAGGNVEAFVTTDNVAVGAKGASFIIDKLGAEGGEVA
                     IIEGKAGNASGEARRNGATEAFKKASQIKLVASQPADWDRIKALDVATNVLQRNPNIK
                     AIYCANDTMAMGVAQAVANAGKTGKVLVVGTDGIPEARKMVEAGQMTATVAQNPADIG
                     ATGLKLMVDAEKSGKVIPLDKAPEFKLVDSILVTQ"
     gene            complement(28294..29184)
                     /gene="alsR"
                     /locus_tag="RN951_002070"
                     /gene_synonym="rpiR"
     CDS             complement(28294..29184)
                     /gene="alsR"
                     /locus_tag="RN951_002070"
                     /gene_synonym="rpiR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418513.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="als operon DNA-binding transcriptional repressor
                     AlsR"
                     /protein_id="HDX2527071.1"
                     /translation="MSQSEFDSALPNGIGLAPYLRMKQEGMTENESRIVEWLLKPGNL
                     SCAPAIKDVAEALAVSEAMIVKVSKLLGFSGFRNLRSALEDYFSQSEQVLPSELAFDE
                     APQDVVNKVFNITLRTIMEGQSIVNVDEIHRAARFFYQARQRDLYGAGGSNAICADVQ
                     HKFLRIGVRCQAYPDAHIMMMSASLLQEGDVVLVVTHSGRTSDVKAAVELAKKNGAKI
                     ICITHSYHSPIAKLADYIICSPAPETPLLGRNASARILQLTLLDAFFVSVAQLNIEQA
                     NINMQKTGAIVDFFSPGALK"
     gene            29543..29992
                     /gene="rpiB"
                     /locus_tag="RN951_002071"
     CDS             29543..29992
                     /gene="rpiB"
                     /locus_tag="RN951_002071"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional allose-6-phosphate
                     isomerase/ribose-5-phosphate isomerase RpiB"
                     /protein_id="HDX2527072.1"
                     /translation="MKKIAFGCDHVGFILKHEIVAHLVERGVEVIDKGTWSSERTDYP
                     HYASQVALAVAGGEVDGGILICGTGVGISIAANKFAGIRAVVCSEPYSAQLSRQHNDT
                     NVLAFGSRVVGLELAKMIVDAWLGAQYEGGRHQQRVEAITAIEQRRN"
     gene            30061..30390
                     /gene="yjdP"
                     /locus_tag="RN951_002072"
     CDS             30061..30390
                     /gene="yjdP"
                     /locus_tag="RN951_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YjdP"
                     /protein_id="HDX2527073.1"
                     /translation="MKRFPLFLLFTLLTLSTVPAQADIIDDTIGNIQQAINDAYNPDR
                     GRDYEDSRDDGWQREVSDDRRRQYDDRRRQFEDRRRQLDDRQRQLDQERRQLEDEERR
                     MEDEYGR"
     gene            complement(30537..31295)
                     /gene="phnP"
                     /locus_tag="RN951_002073"
     CDS             complement(30537..31295)
                     /gene="phnP"
                     /locus_tag="RN951_002073"
                     /EC_number="3.1.4.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism protein PhnP"
                     /protein_id="HDX2527074.1"
                     /translation="MSLTLTLTGTGGAQGVPAWGCECAACARARRSPQYRRQPCSGVV
                     KFNDAITLIDAGLHDLADRWSPGSFQQFLLTHYHMDHVQGLFPLRWGVGDPIPVYGPP
                     DEQGCDDLFKHPGLLDFSHTVEPFVVFDLQGLQVTPLPLNHSKLTFGYLLETAHSRVA
                     WLSDTAGLPEKTLKFLRNNQPQVMVMDCSHPPRADAPRNHCDLNTVLALNQVIRSPRV
                     ILTHISHQFDAWLMENALPSGFEVGFDGMEIGVA"
     gene            complement(31297..31731)
                     /gene="phnO"
                     /locus_tag="RN951_002074"
     CDS             complement(31297..31731)
                     /gene="phnO"
                     /locus_tag="RN951_002074"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoalkylphosphonate N-acetyltransferase"
                     /protein_id="HDX2527075.1"
                     /translation="MPACELRPATQYDTDAVYALICELKQAEFDHHAFRVGFNANLRD
                     PNMRYHLALLDGEVVGMIGLHLQFHLHHVNWIGEIQELVVMPQARGLNVGSKLLAWAE
                     EEARQAGAEMTELSTNVKRHDAHRFYLREGYEQSHFRFTKAL"
     gene            complement(31718..32275)
                     /gene="phnN"
                     /locus_tag="RN951_002075"
     CDS             complement(31718..32275)
                     /gene="phnN"
                     /locus_tag="RN951_002075"
                     /EC_number="2.7.4.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 1,5-bisphosphokinase"
                     /protein_id="HDX2527076.1"
                     /translation="MMGKLIWLMGPSGSGKDSLLAELRLREQTQLLVAHRYITRDASA
                     GSENHIALSEQEFFTRAGQNLLALSWHANGLYYGVGVEIDLWLHAGFDVLVNGSRAHL
                     PQARARYQSALLPVCLQVSPEILRQRLENRGRENASEINARLARAARYTPQDCHTLNN
                     DGSLRQSVDTLLTLIHQKEKHHACL"
     gene            complement(32275..33411)
                     /gene="phnM"
                     /locus_tag="RN951_002076"
     CDS             complement(32275..33411)
                     /gene="phnM"
                     /locus_tag="RN951_002076"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HDX2527077.1"
                     /translation="MIINNVKLVLENEVVSGSLEVQNGEIRAFAESQSRLPEAMDGEG
                     GWLLPGLIELHTDNLDKFFTPRPKVDWPAHSAMSSHDALMVASGITTVLDAVAIGDVR
                     DGGDRLENLEKMINAIEETQKRGVNRAEHRLHLRCELPHHTTLPLFEKLVQREPVTLV
                     SLMDHSPGQRQFANREKYREYYQGKYSLTDAQMQQYEEEQLALAARWSQPNRESIAAL
                     CRARKIALASHDDATHAHVAESHQLGSVIAEFPTTFEAAEASRKHGMNVLMGAPNIVR
                     GGSHSGNVAASELAQLGLLDILSSDYYPASLLDAAFRVADDQSNRFTLPQAVKLVTKN
                     PAQALNLQDRGVIGEGKRADLVLAHRKDNHIHIDHVWRQGKRVF"
     gene            complement(33408..34088)
                     /gene="phnL"
                     /locus_tag="RN951_002077"
     CDS             complement(33408..34088)
                     /gene="phnL"
                     /locus_tag="RN951_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnL"
                     /protein_id="HDX2527078.1"
                     /translation="MINVQNVSKTFILHQQNGVRLPVLNRASLTVNAGECVVLHGHSG
                     SGKSTLLRSLYANYLPDEGQIQIKHGDEWVDLVTAPARKVVEIRKTTVGWVSQFLRVI
                     PRISALEVVMQPLLDTGVPREACAAKAARLLTRLNVPERLWHLAPSTFSGGEQQRVNI
                     ARGFIVDYPILLLDEPTASLDAKNSAAVVELIREAKTRGAAIVGIFHDEAVRNDVADR
                     LHPMGASS"
     gene            complement(34199..34957)
                     /gene="phnK"
                     /locus_tag="RN951_002078"
     CDS             complement(34199..34957)
                     /gene="phnK"
                     /locus_tag="RN951_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnK"
                     /protein_id="HDX2527079.1"
                     /translation="MNQPLLSVNNLTHLYAPGKGFSDVSFDLWPGEVLGIVGESGSGK
                     TTLLKSISARLTPQQGEIHYENRSLYAMSEADRRRLLRTEWGVVHQHPLDGLRRQVSA
                     GGNIGERLMATGARHYGDIRATAQKWLEEVEIPANRIDDLPTTFSGGMQQRLQIARNL
                     VTHPKLVFMDEPTGGLDVSVQARLLDLLRGLVVELNLAVVIVTHDLGVARLLADRLLV
                     MKQGQVVESGLTDRVLDDPHHPYTQLLVSSVLQN"
     gene            complement(34954..35799)
                     /gene="phnJ"
                     /locus_tag="RN951_002079"
     CDS             complement(34954..35799)
                     /gene="phnJ"
                     /locus_tag="RN951_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HDX2527080.1"
                     /translation="MANLSGYNFAYLDEQTKRMIRRAILKAVAIPGYQVPFGGREMPM
                     PYGWGTGGIQLTASVIGESDVLKVIDQDADDTTNAVSIRNFFKRVTGVNTTERTDDAT
                     VIQTRHRIPETPLTEDQIIIFQVPIPEPLRFIEPRETETRTMHALEEYGVMQVKLYED
                     IARFGHIATTYAYPVKVNGRYVMDPSPIPKFDNPKMDMMPALQLFGAGREKRIYAVPP
                     FTRVESLDFDDHPFTVQQWDEPCAICGSTHSYLDEVVLDDAGNRMFVCSDTDYCRQQS
                     EAKNQ"
     gene            complement(35792..36856)
                     /gene="phnI"
                     /locus_tag="RN951_002080"
     CDS             complement(35792..36856)
                     /gene="phnI"
                     /locus_tag="RN951_002080"
                     /EC_number="2.7.8.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate synthase subunit PhnI"
                     /protein_id="HDX2527081.1"
                     /translation="MYVAVKGGEKAIDAAHALQESRRRGDTDLPELSVAQIEQQLNLA
                     VDRVMTEGGIADRELAALALKQASGDNVEAIFLLRAYRTTLAKLAVSEPLDTTGMRLE
                     RRISAVYKDIPGGQLLGPTYDYTHRLLDFTLLANGEAPTLTTADSEQQPSPHVFSLLA
                     RQGLAKFEEDSGAQPDDITRTPPVYPCSRSSRLQQLMRGDEGYLLALAYSTQRGYGRN
                     HPFAGEIRSGYIDVSIVPEELGFAVNVGELLMTECEMVNGFIDPPGEPPHFTRGYGLV
                     FGMSERKAMAMALVDRALQAPEYGEHATGPAQDEEFVLAHADNVEAAGFVSHLKLPHY
                     VDFQAELELLKRLQQEQNHG"
     gene            complement(36856..37440)
                     /gene="phnH"
                     /locus_tag="RN951_002081"
     CDS             complement(36856..37440)
                     /gene="phnH"
                     /locus_tag="RN951_002081"
                     /EC_number="2.7.8.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HDX2527082.1"
                     /translation="MTLETAFMLPVQDAQHSFRRLLKAMSEPGVIVALHQLKRGWQPL
                     NIATTSVLLTLADNDTPVWLSTPLNNDIVNQSLRFHTNAPLVSQPEQATFAVTDEAIS
                     SEQLNALSTGTAVAPEAGATLILQVASLSGGRMLRLTGAGIAEERMIAPQLPECILHE
                     LTERPHPFPLGIDLILTCGERLLAIPRTTHVEVC"
     gene            complement(37437..37889)
                     /gene="phnG"
                     /locus_tag="RN951_002082"
     CDS             complement(37437..37889)
                     /gene="phnG"
                     /locus_tag="RN951_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HDX2527083.1"
                     /translation="MHADTATRQHWMSVLAHSQPAELAARLNALNITADYEVIRAAET
                     GLVQIQARMGGTGERFFAGDATLTRAAVRLTDGTLGYSWVQGRDKQHAERCALIDALM
                     QQSRHFQNLSETLIAPLDADRMARIAARQAEVNASRVDFFTMVRGDNA"
     gene            complement(37890..38615)
                     /gene="phnF"
                     /locus_tag="RN951_002083"
     CDS             complement(37890..38615)
                     /gene="phnF"
                     /locus_tag="RN951_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism transcriptional regulator
                     PhnF"
                     /protein_id="HDX2527084.1"
                     /translation="MHLSTHPTSYPTRYQEIAAKLEQELRQHYRCGDYLPAEQQLAAR
                     FEVNRHTLRRAIDQLVEKGWVQRRQGVGVLVLMRPFDYPLNAQARFSQNLLDQGSHPT
                     SEKLLSVLRPASGHVADALGITEGENVIHLRTLRRVNGVALCLIDHYFADLTLWPTLQ
                     RFDSGSLHDFLREQTGIALRRSQTRISARRAQAKECQRLEIPNMSPLLCVRTLNHRDG
                     ESSPAEYSVSLTRADMIEFTMEH"
     gene            complement(38636..39423)
                     /gene="phnE"
                     /locus_tag="RN951_002084"
                     /pseudo
     CDS             complement(38636..39423)
                     /gene="phnE"
                     /locus_tag="RN951_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313113.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
     gene            complement(39529..40545)
                     /gene="phnD"
                     /locus_tag="RN951_002085"
     CDS             complement(39529..40545)
                     /gene="phnD"
                     /locus_tag="RN951_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDX2527085.1"
                     /translation="MNAKIIASLAFTSMFSLSTLLSPAHAEEQEKALNFGIISTESQQ
                     NLKPQWTPFLQDMEKKLGVKVNAFFAPDYAGIIQGMRFNKVDIAWYGNLSAMEAVDRA
                     NGQVFAQTVAADGSPGYWSVLIVNKDSPINNLNDLLAKRKDLTFGNGDPNSTSGFLVP
                     GYYVFAKNNISASDFKRTVNAGHETNALAVANKQVDVATNNTENLDKLKTSAPEKLKE
                     LKVIWKSPLIPGDPIVWRKNLSETTKDKIYDFFMNYGKTPEEKAVLERLGWAPFRASS
                     DLQLVPIRQLALFKEMQGVKSNKGLNEQDKLAKTTEIQAQLDDLDRLNNALSAMSSVS
                     KAVQ"
     gene            complement(40570..41358)
                     /gene="phnC"
                     /locus_tag="RN951_002086"
     CDS             complement(40570..41358)
                     /gene="phnC"
                     /locus_tag="RN951_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HDX2527086.1"
                     /translation="MQTIIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKS
                     TLLRHLSGLITGDKSVGSHIELLGRTVQREGRLARDIRKSRAHTGYIFQQFNLVNRLS
                     VLENVLIGALGSTPFWRTCFSWFTGEQKQRALQALTRVGMVHFAHQRVSTLSGGQQQR
                     VAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALR
                     YCERIVALRQGHVFYDGSSQQFDNERFDHLYRSINRVEENAKAA"
     gene            complement(41491..41934)
                     /gene="yjdN"
                     /locus_tag="RN951_002087"
                     /pseudo
     CDS             complement(41491..41934)
                     /gene="yjdN"
                     /locus_tag="RN951_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418531.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family metalloprotein YjdN"
BASE COUNT         9269 a        11283 c        11679 g         9909 t
ORIGIN      
        1 gggagagatt aatgcgcgcg gccttgctca acgccaaagc cggtctggga gcggataaac
       61 tgcgcgcgga acagttcacg ctcacgcgcg ccttccgctg agttatcggt tgccgagaag
      121 aaccagatgc cgaggaatgc cacggtgata gagaacagcg ccgggtattc atacgggaag
      181 atggcttttt cgtgaccaag gatctgtacc caaatcgtcg ggccgaggat catcagtact
      241 actgcggtaa tcagccccag ccagccaccc atcatcgcgc cacgcgtggt cagtttcgac
      301 cagtacatag aaagcagaat gatcgggaag ttacagctcg ccgcgatggc aaacgccagc
      361 cccaccataa aggcgatgtt ctgattctca aacagcacgc cgaggataat cgcaatcacg
      421 ccgaggatca gtacggtgat ttttgatacc cgcagctctt cacgttcggt cgcgcctttt
      481 ttgaagacgt tagcgtacaa gtcatgcgaa accgcggatg cgcccgccag cgtcagaccc
      541 gcaaccaccg cgaggatagt ggcgaaagca accgctgaaa taaaaccgag gaacaggttg
      601 ccgcccactg cattcgccag gtgaacggcc gccatgttgt taccaccaat cagatggccc
      661 gccgcgtctt tatattccgg attcgcacca accagcatga tcgcgccgaa gccgataata
      721 aaggtcagaa tatagaagta gcccataaac ccggtggcgt agaacacgct cttacgtgct
      781 tcgcgggcat cgctgactgt aaagaagcgc atcagaatgt gcggcaagcc cgccgtacca
      841 aacatcagtc ccagacccag agagagcgcg gagatcggat ctttcaccag cccgcccggc
      901 ttcatgatgt cgacaccttt cgggtgtacc gccatcgctt cactgaacag attgttgaag
      961 ctaaagccga cgtgtttcat caccataaag gccataaagc tggcaccgaa cagcaacagc
     1021 acggctttga taatttgcac ccaggtggtc gccagcatgc cgccgaacag gacgtacatc
     1081 atcatcagca cgccgaccag caccaccgca atgtgatagt taaggccaaa cagcagctcg
     1141 atcagtttac ctgcgcccac catctgggcg ataaggtaaa gcgccaccac caccagagaa
     1201 ccacaggccg aaagaatacg aatcggccct tgtttcagac ggtaagaggc cacatcggca
     1261 aaggtgtagc gccccaggtt acgcagacgt tcggcaatca ggaacaaaat gatcggccag
     1321 cccaccagga agcccagcga gtaaattaag ccgtcatagc cggaggtaaa caccagcgcg
     1381 gagatcccca agaatgaggc ggcggacata tagtccccgg caatcgccag cccgttctgg
     1441 aagccagtga tattgccgcc tgcggtgtag tagtcgctac gagaacgtac gcgttttgat
     1501 gcccagtagg taatgccgag cgtaaacacg acgaaaatca ggaacataat aatcgcctgc
     1561 cagttcgttg gctggcgctc tacggccccg ctaatagcat ccgcggcgtt agctgcgaaa
     1621 gggagtgtgg cggcaagcgc cgtcagaact cttttcatga tgcttgtacc tcatgcagga
     1681 cttcattatt aagacggtcg aattcgccgt tcgcccgcca gatgtagata ccggtgagaa
     1741 caaaggagat cacaatcact ccaacaccaa ttggaatacc gcgtgtgacg ctggtgttcg
     1801 gattcagcgg cgtgcccagc cagccgggcg cgaaggcgat cagtaaaata aagccgatat
     1861 aaactgccag cataataatc gacaggatgg tggcaaaccg ttgccgtttt tcgactaact
     1921 ccctgaaatg cgcattgtct tctatccgct gataaatagt gccattcatc acagattctc
     1981 cagaggtaat gtagggattg ttttaattcc cgctccctta tgggagaagg ttaacgctcg
     2041 ggtaaccctt gccgaatgta ggccggataa ggcgtttacg ccgcatccgg caatcaatgc
     2101 ctgatgcgac gctgtcgcgt cttatcaggc ctacaaaccg ttaccgactc gcatcgggca
     2161 attgtgggtt acgatggcat cgcgatagcc tgcttctctt caagcagctt ctcgactacg
     2221 ccaggatcgg caagcgtcga ggtatcgccc aggttgctgg tatcgcccgc cgcaattttg
     2281 cgcagaatac ggcgcataat tttgccggag cgggttttag gcagggagtc ggtccagtgc
     2341 agcacgtctg gcgtcgccag cgggccaatc tctttacgca cccagttgcg gacttctgcg
     2401 tacagttctg gtgacggttc ctccccgtga ttaagcgtga cgtaggcgta gatcgcctga
     2461 cctttaatat tgtgcggaat acctactacg gcggcttcgg caatcttcgg atgcgccacc
     2521 agcgccgact caatctctgc cgtccccaga cggtgaccgg agacgttcag cacgtcgtcc
     2581 acacgcccgg ttatccagta atagccatct tcatcgcgac gcgcgccgtc gccgctgaaa
     2641 tacatatttt tgaaggtgga gaagtaggtc tgttcaaaac gttcgtgatc gccaaacagc
     2701 gtacgcgcct gacccggcca ggagtcggtg attaccaggc taccttcggt ggccccctcc
     2761 agcgggttac cttcgttatc gaccagcgcc ggttgcacgc cgaagaacgg acgtgttgcc
     2821 gaaccggctt tcagctcggt agcgccaggc agcggggtga tcatgaaacc gccggtttcg
     2881 gtctgccacc aggtatcgac caccggacat ttctcgttgc cgattttttt ccagtaccac
     2941 tcccacgctt ccgggttaat tggctcgccc acggaaccga gaatgcgcag cgacgaacgg
     3001 tcggtgcctt cgatcgcttt atcgccttcc gccatcagcg cgcggatcgc cgtgggtgcg
     3061 gtatagagaa tattgacctg atgcttgtcc accacctgcg ccatacgggc aggcgtcggc
     3121 cagttgggta cgccttcaaa catcagcgtg gtcgcaccgc aggccagcgg gccgtacagc
     3181 aagtaactgt gtccggtcac ccagcccaca tcggcggtgc accagtagat atcacccgga
     3241 tgataatcaa agacatattt aaaggtcagc gccgcgtaca ccagataacc gccggtagta
     3301 tgcagcacac cttttggctt accggtagaa ccggaggtgt agagaataaa cagcggatct
     3361 tcggcgttca tctcttccgc ctggtgctga tcgctcgctt gctcaaccag gtcgtgccac
     3421 cacaggtcgc gcccttcctg ccagtcaatt ttcccgccag tacgcttcag taccaccaca
     3481 tgctctacgc tggtgacgtt cgggtttttc agcgcgtcat caacgttttt cttcagcgga
     3541 atactgcgcc cggcacgcac accttcgtcg gaagtgatca ccagtcgtga gttggaatca
     3601 ataatgcgcc cggcaacggc ttccggcgag aagccgccga aaatcaccga atgcaccgcg
     3661 ccaatgcggg cgcaggccag catcgcaacc gcggcttccg gcaccatcgg catataaatc
     3721 gccaccacat cacctttttt aatgcccagc tcgagcaggg tattggcgaa gcggcagacg
     3781 tcgcggtgca gctctttata gctgatatgt ttgctctggc tggcgtcgtc gccttcccag
     3841 atgatggcgg tacgatcgcc gttttcttgc agatggcggt caaggcagtt tgccgccaga
     3901 ttcagcgtgc cgtcctcgta ccatttaatg gacacattac cgggggcaaa ggaggtgttt
     3961 ttcaccttct ggtaaggttt gatccagtca agaatttttc cctgttcgcc ccagaaggta
     4021 tcaggtacgt taatagattg ttgatacatc gcctcgtact gctgagggtt tatcaggcaa
     4081 cggtctgcga tgttggcagg aatggtgtgt ttgtgaattt ggctcatgct tttgttctcc
     4141 ttgtaggatg ttaataatat gtggcataag cgttaaatgt aggggtattg gcagttttgt
     4201 ttagtatttg ggcgacagat cacgcaaaag tagaattgtg caaataaacg gcagggtaat
     4261 ttttgaaggt cagcaacaaa agttgattaa ttctttgagg aacatgcagt tatgcatgct
     4321 gttgaaaaag aggaagatac tgactaactc taaagtggta ttttacatgc acttacaatt
     4381 gattaaagac aacatttaca gtgtggttat ttgttacaca taggggcgag caatgtcatg
     4441 acagtgtagg tgcggttact gtcgtgaaaa acaataaaaa ccgccattgc aacaatggcg
     4501 caattcggat gaagccccta tgacaaggat aaaaataaac gcacgccgta tcttcagctt
     4561 attgattcct tttttctttt tcacttctgt tcacgctgaa caaacggctg ctcccgcaaa
     4621 acctgtaact gtggaagcga agaatgaaac ctttgccccg cagcatcccg atcaatatct
     4681 ctcctggaaa gccacctcgg aacagtcaga gcgtgttgac gccctggcgg aagatccacg
     4741 gctggtgatc ctgtgggcgg ggtatccctt ctcgcgcgat tacaacaagc cgcgtggaca
     4801 tgcttttgct gtgaccgatg tgcgtgaaac cctgcgtacc ggtgcgccga aaaacgctga
     4861 agatggtccg ctaccgatgg catgctggag ttgtaaaagc ccggatgtgg cgcgtctgat
     4921 ccagaaagac ggcgaagatg gctacttcca cggtaaatgg gcgcgcggcg gtccggaaat
     4981 cgtcaacaac ttaggttgtg ccgattgcca taacaccgcc tctccagagt tcgccaaagg
     5041 caaaccggag ttaacccttt cccgtccgta tgcggctcgc gcgatggaag ccattggtaa
     5101 accttttgag aaagccggac gtttcgacca gcaatcgatg gtttgcggtc agtgccatgt
     5161 ggagtattac ttcgacggca aaaacaaagc ggttaaattc ccgtgggatg acggcatgaa
     5221 agtcgaaaat atggagcagt attacgacaa aattgccttc tctgactgga ctaactccct
     5281 gtcgaaaacg ccaatgctga aagcgcagca cccggaatat gaaacctgga cagcgggcat
     5341 tcacggtaaa aacaacgtga cctgtatcga ctgccatatg ccaaaagtgc agaacgccga
     5401 aggcaaactc tacaccgacc ataaaattgg taatccgttt gataacttcg cccagacttg
     5461 tgcgaactgc catacccagg acaaagctgc cttgcaaaaa gtggtcgcgg aacgtaagca
     5521 gtcgattaac gacctgaaaa tcaaggttga agatcaactg gttcacgctc acttcgaagc
     5581 gaaagcagcg ctggatgcag gcgcgacgga agctgaaatg aagccaattc aggacgatat
     5641 ccgtcatgcc cagtggcgct gggatctggc gatcgcttcc cacggcattc atatgcacgc
     5701 accggaagaa ggtttacgga tgctcggtac ggcgatggat aaagcggcgg atgcacgcac
     5761 caaactggcg cgcctgctgg cgaccaaagg catcacccat gaaatccaga tcccggatat
     5821 ctcaaccaaa gagaaagccc agcaggccat tggcctgaac atggaacaaa tcaaggccga
     5881 gaagcaggac ttcatcaaaa cggtgatccc gcagtgggaa gaacaggcac gtaaaaacgg
     5941 tctgttaagc caataacccc gttccgcctc gcaaggggcg gaaaacacaa tggagtgaat
     6001 atgagcgtat tacgttcgtt attaactgcc ggggtgctgg cgtcgggcct gttgtggagc
     6061 ctgaacggaa ttaccgctac ccctgcggcg caggcatctg atgatcgcta cgaagttacc
     6121 cagcagcgta acccggatgc cgcctgtctg gactgtcata aaccagatac cgaaggtatg
     6181 catggaaaac atgcttccgt tatcaacccg aataacaaac tgccggtcac ctgcaccaac
     6241 tgtcacggcc agccatcacc gcaacaccgc gaaggggtga aagatgtgat gcgctttaac
     6301 gagccgatgt acaaggttgg agagcagaac agcgtctgta tgtcctgtca tctgccggaa
     6361 cagttgcaaa aagcgttctg gccgcacgat gtccacgtaa ccaaagtggc gtgcgccagc
     6421 tgccattccc tgcatccaca gcaagatacg atgcagacgt taagtgacaa aggacggatt
     6481 aagatttgcg tcgattgcca cagcgatcag cgcaccaatc cgaactttaa cccggcgtct
     6541 gttccgttgc ttaaggagca gccatgacct ggtctcgtcg ccagtttctc accggcgtcg
     6601 gcgtgctggc agccgtcagc ggcaccgcag ggcgcgtggt ggcgaaaacg ttgaatatca
     6661 atggggtgcg ttacggcatg gtgcatgacg agtcgttatg catcggctgt accgcctgta
     6721 tggatgcttg tcgggaagtg aacaaggtgc cggaaggcgt ctcgcgcctg acgattattc
     6781 gtagcgagcc gcagggcgaa tttcctgatg tgaaatatcg cttcttccgt aagtcttgcc
     6841 agcactgcga tcatgcgccg tgcgttgacg tctgcccgac cggtgcgtct tttcgcgatg
     6901 ctgccagtgg gattgtcgat gttaatccgg atctctgcgt cggttgtcag tactgcatcg
     6961 ccgcctgtcc gtaccgcgtg cgctttatcc atccggtcac gaagacggcg gacaaatgcg
     7021 atttctgccg taagaccaat ttgcaggccg gtaagttgcc cgcgtgcgtt gaagcttgcc
     7081 cgaccaaggc gctgacgttt ggcaatctgg acgatcccaa cagtgagatt tcgcaactgc
     7141 tgcgccagaa gcccacttac cgctacaagc tggcgctggg aaccaaaccg aagctgtacc
     7201 gcgtaccgtt taaatacggg gaggtgagcc aatgacgcag acttccgcat ttcattttga
     7261 atcgctggtg tgggactggc cgattgccat ctacctgttt ttgattggta tttctgctgg
     7321 tctggtgacg ctggccgtgc tgttacgtcg cttctacccg caggcgggcg gtgcagacag
     7381 tacgttgctg cgcaccacgc tgattgtcgg gccgggcgcg gtgatcctcg gtctgttgat
     7441 cctcgtcttc cacctgacaa gaccgtggac cttctggaag ctgatgttcc actacagttt
     7501 tacctcggtg atgtcgatgg gggtgatgct gtttcagctc tacatggtgg tgctggtgct
     7561 gtggctggcg aaaatctttg aacatgattt gcttgccctg caacaacgct ggttgccgaa
     7621 gctggggatc gtgcaaaagg ttctgagcct gctgacgccc gttcatcgcg gactggaaac
     7681 attgatgctg gtgctggcgg tgttgttggg ggcttatacc ggctttctgc tgtcggcgct
     7741 gaaatcgtat ccgttcctca ataacccgat cctgccggtg ctgttcctct tctccggcat
     7801 ctcgtccggt gcggcggtgg cgctgatcgc catggcgata cgccaacgca gtaacccgca
     7861 ttccacggaa gcgcagtttg tacaccgtat ggaaatccct gtggtatggg gtgaaatctt
     7921 cctgctggtg gcgttttttg tcggtctggc gctgggcgat gacggtaaag ttcgtgcgct
     7981 ggtggcggca ttaggtggcg gtttctggac gtggtggttc tggcttggtg tcgccgggct
     8041 ggggctgatt gtgccaatgc tgctcaaacc gtgggtcaat cgcagttccg gcattcctgc
     8101 cgtgctggcg gcgtgtgggg ccagtctggt cggcgtgttg atgctgcgct ttttcattct
     8161 ctacgccgga cagttgacgg tggcgtaagc cagaaaagag gtggtttctg gacgtattcc
     8221 ttcctgaagt cggttttctg gcgttgttgt taagtctcgg ggtcaacgtg ttgaccccgt
     8281 tgacggcctt cgcgggagtg cggttgcgct ggcctgccat gatgcgactc acttgcatcg
     8341 gcattctggc gcagttcgcg ctcctgctgc tcgcctttgg cgtactgacg tattgttttc
     8401 tcatcagcga tttctcggtc atttatgtcg cgcaacatag ctatagcctg ctgtcgtggg
     8461 aactcaagct ggcagcggtg tggggcggcc atgaaggttc gctgctgctt tgggtgctgc
     8521 tgctttccgc ctggagcgcg ctgtttgcct ggcattatcg gcagcaaacc gatccgctat
     8581 ttccgctgac gttagccgtt ttatctctca tgctcgccgc actgctactg tttgtggtgc
     8641 tgtggtccga tcccttcgtg cggatatttc caccagcaat cgaaggccgc gatctcaatc
     8701 cgatgctgca acatcccggt cttatctttc atccaccgct gctttacctt ggctatggcg
     8761 gtttgatggt agcggcgagc gtggcgctgg cgagtctact gcgcggcgag tttgatggtg
     8821 cctgcgcccg aatttgctgg cgctgggcgt tacctggctg gagtgcatta acggcgggga
     8881 tcatcctcgg ttcctggtgg gcctactgcg aactcggctg gggcggctgg tggttctggg
     8941 atccggtgga aaacgcctct ttattaccct ggctttctgc cactgcgctg ctgcacagtt
     9001 tgtccctgac acgccagcgg gggatttttt gccactggtc gctgttgctg gcgatagtta
     9061 ctctgatgct gtcgctgctg ggcaccttaa ttgtccgttc tggcattctg gtttcggttc
     9121 atgcgttcgc gctggataac gtccgcgccg tgccgttgtt cagcctgttt gcactgatta
     9181 gccttgcgtc tctggctctg tatggctggc gagcgcggga cggtggcccg gcggtgcatt
     9241 tttcggggtt atcgcgggaa atgttaatcc tcgctacgct gttgctgttt tgcgcagtgc
     9301 tactgatcgt gctggtggga acgctttatc cgatgattta cggcctgctg ggctggggac
     9361 gcctctccgt tggcgcgccg tattttaacc gcgcgacgtt accgtttggt ctgttgatgc
     9421 tggtggtgat tgtgctggcg acgtttgtct ctggcaaacg cgtgcagctt ccggcgctgg
     9481 tagctcatgc gggcgtgctg ttatttgccg ctggggtcgt ggtctccagc gtcagccgtc
     9541 aggagatcag cctgaattta cagccgggtc agcaggtgac gctggcagga tacaccttcc
     9601 gttttgagtg cctcgatcta caagccaaag gcaattacac cagcgaaaaa gcgatagtgg
     9661 cactgtttga ccatcagcaa cgcattggtg aactgacgcc ggagcggcgt ttttatgaag
     9721 cacgccgtca acaaatgatg gaaccgtcaa ttcgctggaa cggcatccat gactggtatg
     9781 cggtcatggg ggagaaaact gggccggatc gttacgcttt tcgtttgtat gtacaaagcg
     9841 gtgtgcgctg gatctggggg ggaggattgt tgatgattgc gggcgcattg ttaagcggat
     9901 ggcgggggaa gaagcgcgat gaataaaggg cttctcacgc tactgctgtt atttacctgt
     9961 tttgcgcacg ctcaggtcgt agacacctgg caattcgcca atccgcaaca acagcaacag
    10021 gcgttaaata ttgccagcca gttacgttgt ccgcagtgcc agaatcaaaa cttactggaa
    10081 tccaacgcgc cggtggctgt cagtatgcgc catcaggttt acagcatggt ggcggagggg
    10141 aagaacgaag tcgaaatcat tggctggatg accgaacgct acggagattt tgttcgctat
    10201 aacccaccgt taacgggtca gacgctggtg ttatgggcgc tgccagtggt gttgttactg
    10261 ctgatggcac tgatcctctg gcgagtgagg gcgaagcgat gaaacagccc aaaataccgg
    10321 tgaaaatgct gacaacactc acgatattga tggtatttct ctgtgtcggc agttatctgt
    10381 taagcccaaa atggcaggcg gtacgtgcgg agtatcagcg tcagcgcgat ccgctacatc
    10441 agtttgccag ccagcaaacc ccggaagcgc agcttcaggc attgcaggat aaaatccgcg
    10501 ctaatccaca aaacagcgaa cagtgggcgt tactgggcga gtactatctg tggcaaaacg
    10561 attacagcaa ttcgttgctg gcgtaccgtc aggcgttgca actacgtggt gagaacgctg
    10621 aactgtatgc ggcgctggcg acggtgcttt attaccaggc cagccagcat atgaccgccc
    10681 agactcgcgc aatgatcgac aaagccctcg cgctggacag taatgaaatc accgccctga
    10741 tgctgctggc ttccgatgcg tttatgcagg cgaactacgc gcaagccatc gaactatggc
    10801 aaaaagtgat ggatctcaac tcaccgcgag ttaaccgaac acagctggtt gagtcgatta
    10861 atatggcgaa attgttgcag cggagattgg attaatcatc tggtgatgaa gattatgtca
    10921 ttgagctgca taaaaaataa tcgaatgaac atatgccaaa aataatcact aatcagtatt
    10981 attgcagatt aaacaaataa aaatctttcc ataacaaatg gttattcatt aatcctgcca
    11041 taaactcgcg ttattatgca ttaatgcagc gaaaagctct gttgttaaag ggttgcgcaa
    11101 cataccgcgc aaatgatact gatcataagc gttaaaaaaa tctacaaacc aacgcaacac
    11161 aattcatgcc ctggcagtat gtcacgttct cgcgtttctg aacggggaac ggcgctccat
    11221 tgaggaagtc attcatatga aaaatataaa attcagcctg gcctggcaga ttctgtttgc
    11281 tatggtgctg ggcattctcc tgggaagcta cctgcactac catagcgaca gccgcgactg
    11341 gctggtcgtc aatttgctct ctccggcggg tgatatcttc atccatctga ttaaaatgat
    11401 tgttgtgccg attgtgatct ccacgctggt ggtgggtatc gcgggtgttg gtgatgccaa
    11461 acagctcggg cgtattggcg cgaaaaccat tatctacttc gaggtgatca ccaccgtcgc
    11521 catcattttg gggatcactc tggcgaacgt cttccagccc ggtgccgggg tggatatgtc
    11581 gcagttggcg accgtcgata tctcgaaata tcagagcact acggaagcgg tacaaagcag
    11641 ttcccacggc attatgggca cgattttgtc gctggtgccg acgaacattg tggcgtcgat
    11701 ggcgaaaggc gaaatgctgc cgatcatctt tttctcggtg ctgtttggtc tggggctttc
    11761 ttccctgccc gcgacgcatc gtgaaccgct ggtgaccgtg ttccgctcca tctctgaaac
    11821 catgtttaaa gtgactcaca tggtgatgcg ttatgcaccg gtgggtgtgt ttgcgctgat
    11881 tgcggtgacg gtggctaact ttggtttctc gtctctgtgg ccactggcga aactggtgct
    11941 gctggtgcat ttcgccattc tgttcttcgc gctggtagtg ctgggaattg tggcgcgcct
    12001 gtgcgggtta agcgtctgga tcctgattcg tattctgaaa gatgagctga ttctggcgta
    12061 ctccactgcc agctctgaaa gcgtgctgcc gcgaattatt gagaagatgg aagcctacgg
    12121 agcaccggcg tcgatcacca gtttcgtggt gccgaccggt tactctttta accttgatgg
    12181 ttcgacgctg tatcaaagta ttgccgctat cttcatcgcg cagttgtatg gcattgacct
    12241 gtccatctgg caggaaatca ttctggtgct gacgctgatg gtgacctcga aagggattgc
    12301 tggcgtgcct ggcgtgtcgt ttgtggtgtt gctggcaacg ctgggtagcg taggtattcc
    12361 gctggaaggt ctggcgttta ttgctggtgt tgaccgtatc ctcgacatgg cgcgtactgc
    12421 gctgaacgtg gtgggtaatg cgctggcggt gctggtgatt gccaagtggg aacacaaatt
    12481 tgaccgtaag aaagcgctgg cttatgagcg tgaagtgctg ggcaaatttg ataaaactgc
    12541 ggatcaataa ttgaagattg ccggggatat ccacccggca atgtgtgaat gcctgatgcg
    12601 acgcttgccg cgtcttatca ggcctatctt aaccgttggt taatttttca aactcttcac
    12661 acccggtatc aaacccttcc atacagctca ggttcaacca gtgcagcgcc ttttgcttgt
    12721 tcttctcgat aaaaccttct tcaccgttta agaacatcat tcccgcccag tactcggaat
    12781 aaccggttcg ggaaattgca gagctgcgtt tgaaatacca ggttgccttg tcatcgtcgg
    12841 ccttaatgcc cacgccgttg gcgtaaatca aaccaagcag catttgggca tcgacggcag
    12901 agtcgttctc cagatcttcc gaggcgtttt ctaacagcga aattgccttt ggataatccg
    12961 gtttacccgc ttgagtattt accagaatat gcgccagcgt tacttcacct tctttactgc
    13021 ccgcttgcgc cgctttctct gcaagaactt ttgcttgtgg atagtccaga ctgaccggat
    13081 tggtgatttt gatctgcgcc agcagcgcgc aggcatcagc atcaccgctg tcggcggctt
    13141 tctgtgccca atattcggct ttgctcaaat cgccggagct aaaccagctg tcggcaagaa
    13201 aatattgtgc gcgtcggtcc ccggcctctg ctgcctttaa atactggctg ccaggctcgg
    13261 agtcgttggc gtgggcaaag aatgtcaaaa acaacatcaa tgcgataatt tttttcattt
    13321 tgataatacg attgggtagg gagtaaccag tataaagagt tcgaatggat aaaaaaacag
    13381 cctccgaaag gaggctgtag aaaggacggt attacgccag tgccgcttcg cgcaggcgag
    13441 ttttcaactt gttgtactcg tcaatcacgt actgctcggc ggcgcgctga tcggcgatcg
    13501 gctcgacgcg aacggcgcag tatttgtact ccggcgtttt cgtaatcggg cttaagtttt
    13561 cggtaaccag ctcgttacag gcaccaatcc accactggta ggtcatgtaa atcgcccctt
    13621 tgttcggacg atcgctgacc tgcgcacggg tgataatttt gcctttacgc gagtgcaccc
    13681 aaaccaatgc ctcatcttca atacccagac gtttggcgtc ttcggtattg atttgtgcgt
    13741 agccaggttc atcagccagc gccgccagtg ccgcacagtt accggtcatc gaacggcaag
    13801 agtagtgacc aacttcacgc accgttgaca gtaccatcgg gtactcgtcg gtgagtttgt
    13861 cgattggcgc tacccagtcg caggtgaaga actgcgccag accgttcggg gtatcaaact
    13921 tctctttaaa cagataagaa gtcccctgat cggcatctga agtatcgcgg caaggccact
    13981 gaatgaagcc cagttcgccc attttctcgt aagtcgcacc gtagaaatcc gggcacagat
    14041 gacgcaactc atcccagatc tcctgggtgt tgttgtagtg catcggataa cccatacggg
    14101 tggcgatttc actgatgatt tgccagtccg ttttcagatc ccatttcggt tcaaccgcct
    14161 tgaagaaacg ctggaagcca cggtcagccg cagtaaacac gccttcatgc tcgccccacg
    14221 acgttgacgg taaaataaca tccgccgccg acgcggtttt ggtcataaag atgtcctgaa
    14281 cgataaccag ttccagatct tcaaaggctt tacgtactgc cgacagctcc gcgtcagttt
    14341 gtagcggatc ttcgcccata atgtacgcgg cacgcacttc gccatgcgct gcgcggtgcg
    14401 gcagctcgct gatgcgatag ccggtatgcg ctggcaggct ttccacgccc caggctttgg
    14461 cgaatttctc gcggttagcc ggatctttca cgtactggta tcccggatac gtatccggca
    14521 gcgcgcccat atcgcaggca ccctgaacgt tgttctgacc acgaaccggg ttaacacccg
    14581 catgcggctt accgaggtta ccggtcagca tcgcgaggct ggtcagagaa cgcacggttt
    14641 ccacgccctg gtagaactgg gttacaccca tgccccacag gatggcggcg cttttcgcct
    14701 gggcatacat ccgtgccgcc tgacgaatct cactggcgct gacgccggtg atatcttcaa
    14761 ccgactccgg cgtgtagcct tcaacgattt tacgatactc ttcaaagcct tctgtacgtg
    14821 aagcgacgaa cgctttgtcg tacagatttt cttcaataat gacatggccc atcgcattca
    14881 acagcgcgat gttcgagccg tttttcagtg caatgtgcat gtcagcaatg cgcgcggttt
    14941 caattttgcg cggatcgcag acgataattt tcgccccgtt acgtttagcg ttaattacgt
    15001 gattcgccac gattgggtgg gaatccgccg ggttgtaccc gaaaacgaac actaaatcgg
    15061 tattatcaat ttcgttaata gcattgctca ttgcgccatt accgaccgat tggtgcagac
    15121 ctgcaaccga tgggccgtgt cagacacgag cgcagcagtc aacgttattg gtaccaataa
    15181 cggcgcgcgc aaatttttgc attacatagt tggtttcgtt acccgtacca cgcgaggagc
    15241 cggtcgtctg gatggcatcc ggaccgtact tctctttgat ggcgctcagg cgctcggcaa
    15301 cgtaattcag tgcctcatcc caggaaacag gttcgagttt gccgccacgc tggcgacgga
    15361 tcatgggggt tttcaggcgc ggggtcagga tctgggtatc gttaatgaag tcccagccat
    15421 aataaccctt cagacacagg gtaccctggt tggttttccc ctgcgctgcc tccgcccgga
    15481 cgattttgcc gttatcgacg accaggttga ttttgcaacc tgatgcgcaa taggggcaaa
    15541 ccgtgacgac ttttttcatc ggtctcgctc cagttaatca aatcacgcat acgcgctctc
    15601 gactacagta tgcatctttt atgccacatt ttatgtgggg tcattccctg atattacggg
    15661 cactatttat tcaaaactct gacgaaaaac aggctgtcgt cagttttgac gtgacgaaac
    15721 gaaataccgc gtgacagcca tcacgcggca gacattttat tttttctcga cgacgggacc
    15781 tgcctgatac ccgccgccca gcgatttcat caactgaatg ctttggatca cccggcggct
    15841 gtccagcatc agtaatgaca tctcttcggc aagcactggc aaccgggctt cggtggcctg
    15901 taagcggctg gttaagccgc gctgataggc ggcctcggca gcgcgctggg taaagcgcgt
    15961 ggcttccacg cgttcagcct gcatttctcg ctcgtcgttg agcgtttgca gacgcgtgcc
    16021 gttgacggca acgtcacgca ccgcgttcag tactgactgg ttgtaacgtt caatcatcat
    16081 gttgctggcg gcgcgcgtgc cttcgagatt ggcattcaac cgtccaccgt caaacagcgg
    16141 caatttcaga cccgggatga agttgaactg gcgactggtt tttttgaata aggtatgcag
    16201 atggatggag tccagaccga aaaacgcttt gatatcaaag ctcggataga acaacgcccg
    16261 cgcggaatcc acctgatcta atgacgcctg aacataccag cgcatggctt gcagatccgg
    16321 gcgtctggcg agcaactcat aagagagtgt cgccggaatg ccggtctgga cttgcggtaa
    16381 tgccaccggt ctgatctccg gcatatcgct ggctcccgcg ccaatcaatg cacgcagaga
    16441 ttctcgcgtt tcggtgattt gccctttgac ggcaacaatt tgtttatcga ccgccagaat
    16501 ctgtgcccgc gcgccgtgga aaggcacttg cgcttccaga ccgtgcgcca ctttactctg
    16561 gtgcgctttc accgcgtaat caatcacatc gtgagtttgt tctaacagat cgagcatctg
    16621 atagctggcc tgcatactgt aataaagctg cgctacgccc gtggccagcg atagctctac
    16681 tgctgcggtt tctgccagcg cggcattatg cgcgccaatg gcggcggcaa ccgctgagcg
    16741 atgcacaccc cacaaatcaa gatccagtcc ggcaaacaaa cctactgtgg cttccgtata
    16801 gtacggcccg tccataccca gtgctggcgc atccattgaa taagggctta aaaagccgtt
    16861 cgccgagaca cgttggcggt tgagcatccc taacgctgcg acctgtaatt gtgaaccggc
    16921 atctaacaaa tcggcctggg actgcgcttt ttcttcccgc agtttcgctt cggcgagggt
    16981 gtgtgaacca cttagcgtcc gttggatcag cgcatccagc tgcgggtcat tgagttgttt
    17041 ccaccactgc gcctgcggcc agccggagct ggcaagatga atatcgtcgg ccagtttgat
    17101 ttgttccggt ttgagctgtt gatgaggtgc agaatcctta cgtaccaggg cacagccgga
    17161 aatcagcgtc gtgctgccga gaatgctgca caacagcaga cgtgaaagtt gacgattgat
    17221 cattgcgtgg ctccttgtgc ctgttccgtg gcgggcgtta atgccggggc tgtccagtct
    17281 ggcaagcggg cgaaaagctg gcagacgtgt tgctcctgtt ttaataaggt gggcaggatg
    17341 gcctgagagg cgggtgtctc ttcaagcgtt atttgaggag aacggctgag tgcggttgcc
    17401 agaccggcag cgtatttctc cagggcgtcg gcaaactgac ctgctctgtc cggctgtagt
    17461 gcgttatcca gcgcctgcgc cgagttccag gtggcatccc aggcgtgaag aagatcgcgg
    17521 ccctgacgaa taaccgtttg cgaacgttca atcagtaatg cgcgttcttc gctgtccagt
    17581 tgacgctcca gcgccacgcg ttggcacatc tcttcacagg cattaaacgc cgcatgcaga
    17641 ccgatacgaa tttgcagata agtgcgcaga gccgtgactt cctgctggcg tgggatccgc
    17701 attactttac ttaacatacc cagcgtgcca gccagttttt gcggcagtgt gcgcgcttca
    17761 ctttcaggcc agacaaaggt gtaaatcacc gcggacacca cggtaccaat gatgataccc
    17821 agggcgcgat cgcgaatttc caccaggtcg tacactgggc caaaaacgtt ttcgagcgtg
    17881 gcgagcgcga aggtgaccac catctgtgtg ccgatataag aagagcgttc agagctggtg
    17941 gcaatccatg cgcccaacag gaaaatcggt gccagcacaa acagcaattc gacaatattg
    18001 tccagccagg gcatgaccag tagcgtgaat aacagcgcca gaatcgcgcc gcaaaaggcc
    18061 ccgccaaaac gcagcaccat cttctggtac gacgaaccga catttgggtt agcgacgatc
    18121 acgcatgtca gcatacaggt gtgaatgcct tcccagtcca cgccgctgta aaaggtgtaa
    18181 cagatcaaac aggcgagcag cgtttttacc gcgtagcgca tatagtctgg attggtaaaa
    18241 gcatcggcgg ccattgatgg cggtttggct gcgggcgttg gcggcgtatt cgggtccatc
    18301 tgacccagtt gtaacaacgt ctggcagata ttctccaggt tacattcccg tgccgccatc
    18361 gcttcacttt cactgatccg ccagtcgctt tgccagcact gaccttcagc aacggcatgc
    18421 tgcagcttgt tgatttctga agctaatttt tgtcggaatt caataattgc ctgagaatca
    18481 gcaaaagagg tgggatcgta gcgattcagc gtcgagtaaa tgtaggttac cgttgccacg
    18541 cagctttgcc accatgcgtt ttgagttcgc cagttggcat cgtccgcgag gcaaaagaca
    18601 ttgagttttt gtagcgccag cgcctctctt tcaatccgcg tttcgggtag cggtacgagg
    18661 ctgtctgtca ggtgactaat ggcatcatca agccgatcat taagcgcctg atgcatttgc
    18721 gaaatggcac gactgggaaa ccacagcacg ccgattaacg tcatcagcaa ggttggatag
    18781 aggccaacaa cgatacacca cagcgttaag cgcacgacca cttccggata gtcgagcatg
    18841 gcggggaagg tttgcccgta aatagcgaca atggcgacgg cgaaaaagac cagccccaag
    18901 cgatgggtgc gcatcaaaaa catgcagccc atcaggatcg gtccggcgat gatcaatcgg
    18961 atcaacggtt cgccgtatga ccatttgtag atcaaaaaca ggctgccgat ctccagcacc
    19021 gtggcaacca caaacaagat cgcgacaaat ttggtgtaaa acgcgttcga ctgaataccg
    19081 taaaacagca ctgccagcga taacgccaca aaagggatct caaaggtcat cgagatcaga
    19141 atcaccagca ggcagcctac ccagagttgc acggtctgcg gcacgcgacc tggtcgccgc
    19201 tcgcttaact cttcatgaaa gaacgccagc agcctgacca ccggtaatgg cagggagttg
    19261 agcgcgctca ttattgcggc tcaagattag cgactgccga agcgccgatg cggaacattt
    19321 ccgggtcagg tttatcgacc atgattttga ccggaaaacg ctgggcaacg cggacccagt
    19381 taatagaacg agacactttc ggcaggccgc ccagcaccag gccgccgtca tccggtagca
    19441 cgccgtagcc aatcgaatcc actttaccct cgaaggtttt gccgctgtca ctcatcaggc
    19501 gaatcgttgc gggtgtacct gagcgaatat ttttcagatc ggtttcgcgg aagttggcga
    19561 tcacatacca gtgacgagtg tcgattaggg taaaaatagg gcgcatggca gaagcaaatt
    19621 gcccgacgga ggttttgagg gaaatgaccc ggccatcaaa cggcgcgcga acggtcgcca
    19681 tttccagatg cagtttggtc agggcaatat ccgcttcgac cgccgcacgc tgggcaacta
    19741 atgcatccac gccgctgacg gcgctggcgg ctgactgcgc ctgtaacaat acggcattaa
    19801 gatccgcttc tgcggcgcgc tgcgccgttc ttgcacggtc aacatcttcc gctgagacaa
    19861 aaccttcttt cagtaatggc tcggtgcggc gtaatgtatc tgtggcctgt ttcgcggcgg
    19921 cacgggcttt ttctaccgtg gcattaaccg agtcggcacc aaactgttgc gcgtcaacgc
    19981 tacgctgggt gagcataatt tgcttatcca gcgccgcgag ggaggcttca gctttcgcca
    20041 gattggcttc gtacgggcgc gggtcgatgc ggaacagcaa atcgccctgt ttgactgcct
    20101 ggttgtcggt gaccgccagt tctacaatgc ggccgctgac ttccggtacc acatcaatgg
    20161 tatctgctga cgcgtaagcg tcattagttg atggcgcact gtctacgcgc cagataacga
    20221 aaacaagggc aaccagcgcc aacgcaacca ctaacagagc agggaattta ctgcgaggag
    20281 cttttttcgg cgtactttcc atgagcgcgt ctcaaataga ttagaaaaat gccagccaga
    20341 acagcatggc gtagagagca aaaagggcgg tataaataat tccgacaaat gccagattga
    20401 tatttgcccg ctgaataact cgcctcgtga tgagcgtcaa aataaggctg gcaatggcgc
    20461 agaaaaacca gctgggataa taagcgccga tcaccgggat tgccggagat aatgagcatc
    20521 ccgaaaccat gaagacggga attatccagg ctgttttttt gagttgcatc gccatgcgag
    20581 agagaactgt tggcatatta aatacatcct gtctgctgcg aacaatatct gtagtgaata
    20641 tcaatatcca ttgaaggcgt cagtatggct attttcttga tgaataaaaa tagctttatt
    20701 cagccaccgc attcataact tatatatttt atttattaat tggctgtata tatttttaaa
    20761 ataaatactt ttgggggctt cagcgccccc aaaagcgagt gacattaatt tggggttacg
    20821 atattcaccc acaaatcgaa attatccaga caggcgataa tttcttccag tttcgcgcca
    20881 ttgccaataa ttttggcttt cttcgctttt accagatccg ccattttggc ttgtccggtc
    20941 agcacggcgt gcagatcttc acggctgatg tagaaagagg cgtcggcttg cggttgcagc
    21001 gttttccggt agttaagcac gctatcgttc agcgtcaggt tgaggttatc gccgttgctc
    21061 atattgaagt tcaggctgat atttttaccc gcagctttcg cgctatcgag gcgaacggcc
    21121 ataaagtcga acagcatttc gaccgacatc ccgcgaatgg tgtccgggga accggtggtg
    21181 ccgtggctga acttatgcac cccttcgcgc agctctttcg cgccggtcag gtagaaaccg
    21241 cgccatgtgg cggactcggc ctgatagccc agctgttcaa agttattcgc ttgcagattc
    21301 ttcgcgacct ggtcacccgg gttggcggca atcacctgtt tcagcagttc tgccgaccag
    21361 cggtaatcac cttgcttgtt cgcttcttgc gccaggttga tgacacgggc agaaccgccc
    21421 agcgcctgca cgtaacgttt acccatctcc acctgaccat acggatgcag gttagccggg
    21481 ttaccgtcgt aatagccaag atagaagtta tacaccgcgc gggcgttgtg gctgacagaa
    21541 ccgtaatagc cgcggctggc ccagttattg gcaagtgcag gcggcagctt aatcatgtcg
    21601 ccgatttcat tcatggtgta gccctggttc gccaggtgca gggtctggtc gtgaatgtac
    21661 ttgatggtat cgcggtattt accaatataa tcattgatat gcttattgcc ccagaccggc
    21721 caggtgtgcg gcataaacag cacttccgcg tcgttacccc acatatccag cgtttcgttc
    21781 agatactcgg tccacttgct ggtgtcgcgg gttttcgcgc cgcgcagagt gtagaagttg
    21841 tgcagggtat gcgtggcgtt ctcggcggta cacagggctt tcagggccgg aatatagaag
    21901 tgcatttcgg ctggcgcttc gctacctggg gtcatcagga agtcaaactc caggccgtcg
    21961 ataatcatct tctcgccagt tctgacgata gttttcgtcg gtgcaataat gctcgggtcg
    22021 cccgttgcca gcgtcacgcc aaggccatta cccacattgc cttgcgcgtt gtgcggcagt
    22081 aacagaccgt aagagtagag cgcacggcgg ctcatgatgt tacccgccag cacgttttcg
    22141 ctgatggctt cgtccataaa gcctgcaggg gcaatcacct gaactttgcc ggatttaaca
    22201 tcggcttcag agataatgcc tttcacgcca ccatagtggt cggtgtggct gtgagtgtag
    22261 ataacggcaa caatcggttt ttgcggacga tgctggaagt aaaggtcaag tgcggctttt
    22321 gcggcaggcg gcgtcaccag cgggtcgata acaataatgc ctttctcgcc ctcaacgaac
    22381 gtaatgttag agatatcctg gccgcgcacc tgatacattt tatcggtgac tttgaacagg
    22441 ccagaaatac cgttgatttg cgactgacgc cacaggctgg ggtttacggt ttccggcgct
    22501 gcggcattaa tatcaaattt gtaatcgtcc gcgcggtagt aaactttacc gttcgcatca
    22561 cgcagaatac cttcatccag cagcggggcg ataaatccac gctgggcatc gtcaaaatcc
    22621 tgacgatcgc taaacggtaa tgatttggcg taattctgat taacctgttg ggtatattga
    22681 gtggcggctt tcgcttcctc tttcgcgtta gcggtattta ccatcatgcc gctggcggca
    22741 gttaacgcaa taacaatcct gctcaaacgg aataaccgag agttattcat ataaatctcc
    22801 atttatcatt tatgtcgtaa atatgtaatc catgcaaaat acgtcattta aagctggcgt
    22861 tatcataatt gggaaattgc gactttaata agtggaagtg tgagcggaac gcgccatttt
    22921 attaggcatt tgtgctgaag agggaaaatt acagtaaaac tatcattgca gaaaataata
    22981 tgagtcgttt tatgtgttta ttatatatat tgtacctgtc gttggcacag cgggacattg
    23041 cgctactgtg ccaacgtttt actcatgggg ctttagcaca gaactgtggc aaaaaacgtt
    23101 gatgcgccaa tattgctgca ccctgagcgc cattaaagtc agaagatgag gcggcaataa
    23161 agcgcacgac ctgatgcggc agtggacggc gcaggtactt ttgggtcatg gcaacgagag
    23221 tctcgcgtgg gaaggcgggc atatccatca cgccaccgcc caggatcacc gcatcgggat
    23281 cgaacagatt aatgctggtg gcaatggccc gtgccgcgtt ttcaagcaga ctctggacga
    23341 aaggggcgtt ttccgcatgg acgaaaagat cgcgcaatgg gtaatttcgg ggctgttgtt
    23401 cgtaccagcg tcttagcgcc attccagagc aattggtttc caggcaccca ggattgccac
    23461 acgcgcagtg ttgggtcata tctcccaggg ggatatgacc cagttcgcct gccacaccgt
    23521 gtgcacccgt ccacggcgca ccgttcatcc acactgcgaa ccccatcccc gtaccgagat
    23581 aggccgccag aaccagttgt tgcgtaaggc ggttttctac tacgtcccag gagagttgca
    23641 ggttaacgtc gcgggaaaac tcaaccggac aattcagcgt attttcgagc ttatcggcga
    23701 gatcatataa atccgccgct gttaacggca ggttaggcgt agaaataatg gtgcgtttat
    23761 ctttactgac cagcgccgga aatcccatca ccagaccatg acagcgagcg ttaaagcgcc
    23821 tgagttgctc gtcaatcatt tcgccgatac ccgacaccag gccgggagca atgacttctg
    23881 cggtccgctt tttttcgcag tgtagcgttt caccttctgc tgtccgcaga caaaagcgga
    23941 tatgcgttgc ccccatatcc acgcccgcta cgacgttatg ctgtttttgc atgaggctgt
    24001 acctcgcttt ttgcagccag aatctgcgcg gtcataattc tccatgcttc gtcgatattt
    24061 tccgcatgat taaacaggcc ggaagtgccg acgataaaga catccgcccc tgccgccatc
    24121 agtttttcgt aagttgcctg gttgcaggaa ccgtccacct caatttcgta ctccagacct
    24181 tctcgttcac gccatgcctt cagttcggca agtttatcca gcatttcagg aatgaacggt
    24241 tgtccggcaa agccgggatc gacagtcatg accgtaattt tatcggcctt atggatatag
    24301 tatttcatgg cctcaactgg cgtctccggg ttaaggatca gccccacttt catgtcatga
    24361 cggcggattt catcaatcag gcggaacgcc tggccgttga tggtttccgg atgcagagtg
    24421 atgaaatctg ctcccgcacg cgccagttga gcaatgtaat cctgcggccg cgtcaccatc
    24481 agatgacagt cgagcggttt agttgccagt tttttaacct gacttacgaa gaacggtgag
    24541 agtgtcagat tggggacaaa gtgaccgtcc atgatatcga tgtggaagta atcggcatgg
    24601 ctgtcgataa attcgatctg ttctttaaat ttcagcagat ccatacacat taacgagggg
    24661 gagattttca tgttcaattc cttacttact gataagacgg tcaagggcga cagccgcgat
    24721 aattaatccg cccatcacca ccagttggta ataggtttgt acctgcaaaa tattcagacc
    24781 gttgttgatg gtgccgatga tcaacccgcc aatcaccaca gagaaaatgc gccccttgcc
    24841 gccgaagaaa ctggtgccgc caatgatggc gctggcaatg gcataggttt caaaacccat
    24901 accggcaagc ggttctgcgg caccgagtcg tgcagttgag acgacgcctg ccagacctgc
    24961 acaaacaccg gagatgataa acaccaccag gatgtggaat ttcacgtcaa tcccggaata
    25021 gaacgccgaa tttttgttgc cgcccagtgc gtagatgttg cgcccgagcc gcatacgcgt
    25081 tgtcagaaac caaaggatga gcgcgacaat tagtgagaag ataacgggga caggtatccc
    25141 aattacgctg gcggcaaaga agttcacgaa gtcaaatgag aagccgtata ccgagttggc
    25201 atcggagatc accagcgtga tcccacggaa aatcgcgttg gtgccaaggg tgatgatgaa
    25261 cgggtgtagc cccgtccagt tgaccaggca gccgttgatc gcccccagtg cgccgccaac
    25321 cagtacaccg ccaatcatcg ctgcgagaaa cgggtcaaca cctgccaaca tcagtttggc
    25381 ggtcaccata ccggaaagcg ccagaatcgc gccaaccgag aggtcgatac cagcgaccag
    25441 gatagcgaaa aactcgccca tgccgatcaa taccgtcacg gagctttgaa caaaaatctg
    25501 ggtaatatta ttggtggtca gaaaatattc tggtgacagc gaaccaaaga tggcgacgat
    25561 gatcgccagg ataaaaaagg tgccgtattt atcccagaac agcgcaaagt tgaacggttt
    25621 cttctcgctc gcttcgcttt ttactcttgt ggtaaagccc atgccataat ctcctcttcg
    25681 ctcatgtcat cgcgattcgt caggatttgc gtcagtcgtc cttcgcagaa cacggcgatg
    25741 cggtcgcaga cggtgataat ttcaggtagt tcagatgaca ccatcaggat gacttttccg
    25801 tcgtccgcca gttggcgcat cactttgtaa atttcggctt tcgcgtcaac gtcgatgccg
    25861 cgggtaggtt catcgaaaat aatcacttcc gggcaacagc acagccattt ggagatcagg
    25921 actttctgct gatttccccc ggagagttcg gtgatattct ggtttaccga atgacatttc
    25981 agcgccagca gttcgcgttg attttcagcg gtacgttgct cgtcaacttc atgaaacaag
    26041 cccatcgcgc ctttatagcc gccgtctttc agactgcggc tgatcgccat gttctgagcg
    26101 attgaaaagt tggggaaaaa accgttatcc cggcggcttt cagtgatgta agccatccct
    26161 tttttcacgg catccagggg tgaacgtgga gagatatctt tgccattaag acggatttct
    26221 ccgccagcgc gtttatccac gccaaacaga caattcatca gttcagtacg tccggaaccg
    26281 accagtccgg caaagcctaa tatttctccc cggcagacgc taaatgagat atcccggacc
    26341 ttttttctgt cacgactggt gacgttccgc acctcaaaaa ccgtttcgtg cgcaaggttg
    26401 ctgacattct ccttcatcgc gttaaaacgg ttttgcagtt cgcggcctac catcagacgg
    26461 acgatatcgt catttgacac atcgcttact atgccgctgc aaacgctgct gccgtctttc
    26521 atcaccgtat agcggtcgca aatacggcga atttccgcca acttatgcga gatatagacg
    26581 atggccgtac cctctttacg caactgattc atgatcagaa acagatagtc cacctcttta
    26641 ttggtgagtg aggaggtggg ttcatccatg atgatgactt tggcatcgag catcagcgtt
    26701 ttggcaattt ctagcatctg cttgtggctg atagataaat tcgccacttt ctcatctaga
    26761 tcaactttca agcccacgcg taataacatc atggcggcgc ggacacgcat ttctcgccag
    26821 tcgataatat tgacgccaca gatttttttc gtcagatgac gaccaatata taaattttcc
    26881 agtacggtta attcatcaat aacgctgagt tcctgataaa taatcccgat accgagttgt
    26941 gccgctaatt tatgatccag cttgttatag ctaatgttat taatggtaat ggtgcctttg
    27001 gtcggctcat gtattccgga taaaactttc attagcgtgg atttacccgc gccattttct
    27061 cctagtaatg catgtatttc accaggataa accgttaaat taactgactt taatgcgtga
    27121 accggaccaa aggacttgcc gatccccgcc atcgatatat atggcgtggc cataaataac
    27181 ctctctgcac gaaatatcgt attattgcct gatggctaca tttatcaggt ctacgttcag
    27241 gttattttgt tggccggata agacacttca ttagcatcat catccggcat cattcagttt
    27301 tattgagtga ccaggattga atcgaccagt ttaaattccg gtgctttatc cagcgggata
    27361 accttgccgg atttctcagc gtcaaccatc agcttcagac ccgttgcgcc gatatccgcc
    27421 gggttctggg caaccgtcgc ggtcatttgt ccggcttcca ccattttgcg ggcttccgga
    27481 atgccatctg taccgacgac cagcactttt cccgtttttc cggcgtttgc gactgcctga
    27541 gcaacaccca ttgccatcgt gtcattcgcg caatagatcg ctttaatatt cggattacgt
    27601 tgcaacacgt tagtggcgac atccagtgct ttaatgcggt cccagtcggc aggctggctg
    27661 gcgacaagct tgatctggct tgcttttttg aaggcttcgg tggcaccatt acgacgcgct
    27721 tcaccggagg cgttaccggc tttaccctca atgattgcga cttcaccacc ttcagcgccc
    27781 aatttgtcaa taatgaacga cgcgcctttc gccccgacag caacgttatc ggtggtgaca
    27841 aaagcttcca cattgccgcc agcttttttc agattatcca tgtcgatttt ttcatcgaga
    27901 ttaaccagat aaatgccttt tttccatgcg cgggcgacag gcatgaccag attcactgag
    27961 gataatggag cgaaggcgat acctttgtaa tttttattac tgagatcttc aaataactgc
    28021 aattgagatt gaaaatcgcc ttctgaagga gaggcaaaaa tatcaacgct gacgcccagt
    28081 gtttttgctt catcttcaat gccttttttc atatctaccc aaaatgggtt ggagagggtt
    28141 ttcaatacga cagcatattc ggcggcagca aaagcgctgg ttgacaacat taagcccacg
    28201 agtgtgccgc tgaaatattt cagatattta ttcataataa tgttctcacg gtaaggggac
    28261 aggtaactcc gcgatggcgg aattaccttt ttcttatttc agcgcgcctg gtgagaagaa
    28321 atcaacaatt gcgccggttt tttgcatatt aatattagct tgttcaatgt tgagctgggc
    28381 gacagagaca aaaaaagcgt ccagcaaagt tagttgtaat attcttgccg aggcattacg
    28441 acctaataac ggcgtttccg gggctggtga gcaaataata taatcggcca gtttcgctat
    28501 cggtgaatgg tagctatggg ttatacaaat aatctttgcc ccgttctttt ttgccagttc
    28561 tacggccgct tttacatcac tggttcgccc ggaatgggtc actaccagca caacatctcc
    28621 ttcctgtaac aacgaagcgg acatcatcat gatgtgagca tcaggatagg cctgacagcg
    28681 tacgccaatg cgcaagaact tgtgctgtac atcagcacag atagcatttg atcctccggc
    28741 accgtacaaa tcccgctgtc tggcctgata gaaaaagcgg gcggcacggt ggatctcatc
    28801 aacgttgacg atcgactgac cttccataat ggtgcgtaaa gtgatgttaa ataccttatt
    28861 caccacatcc tgcggcgctt catcaaaagc caactcggaa ggcaatacct gttctgactg
    28921 agaaaaataa tcttccagcg cactgcgtaa gttacgaaag ccgctaaacc ccagcagctt
    28981 tgatacctta actatcatcg cttcagatac cgccagagct tctgcgacat ctttaattgc
    29041 gggtgcacaa ctcaggttac cgggtttgag taaccactcc acgatgcggc tttcattttc
    29101 tgtcattcct tcctgcttca ttcgcaggta aggcgctaac cctataccgt tcggaagcgc
    29161 tgaatcaaac tctgactggc tcatcacgtt ctcttgtcct tgaattgaag acgccactat
    29221 atcaccacag caagaacaga aaagatgctg gcgacttcac aaaaaaataa aatttataaa
    29281 gtttatttta ttgtgaacaa tggcgagtgg cttaaaattt tatttcattt aattagttta
    29341 aaaacatgat gttatttgtt tttctggttt tttagatgat agatgttgct ggatggtgag
    29401 tgtctttaac gctattgcgc tgtcagatgt aactctgtaa aacagatcag gaaggcgtaa
    29461 ttcatcgatt ttgggtgttt ttaattcatt aacatcacaa atgttttttg attgtgaagt
    29521 tttgcacgga cggggaagat gaatgaaaaa gattgcattt ggctgtgatc atgtcggttt
    29581 cattttaaaa catgaaatag tggcacattt agttgagcgt ggcgttgaag tgattgataa
    29641 aggaacctgg tcgtcagagc gtactgatta tccacattac gccagtcaag tcgcactggc
    29701 tgttgctggc ggagaggttg atggcgggat tttgatttgt ggtactggcg tcggtatttc
    29761 gatagcggcg aacaagtttg ccggaattcg cgcggtcgtc tgtagcgaac cttattccgc
    29821 gcaactttcg cggcagcata acgacaccaa cgtgctggct tttggttcac gagtggttgg
    29881 cctcgaactg gcaaaaatga ttgtggatgc gtggctgggc gcacagtacg aaggcggtcg
    29941 tcatcaacaa cgcgtggagg cgattacggc aatagagcag cggagaaatt gagattcatc
    30001 cactacttgc atggatgagt aatgattaat gtggatagag tttctttttg aggttggcta
    30061 atgaaacgct ttccgctatt tcttttattc accctgctca cgctgtccac cgttccggcc
    30121 caggccgata ttatcgacga caccattggc aatattcagc aggcgattaa tgacgcttat
    30181 aaccctgacc gtgggcgaga ctatgaagat tcgcgcgacg acggctggca gcgtgaagtg
    30241 agcgacgatc ggcgcagaca atatgacgac cgccgccgcc agtttgaaga tcgccgcagg
    30301 cagctggacg atcgccagcg ccagcttgat caggagcgtc ggcaactgga ggatgaagag
    30361 cggagaatgg aagatgagta tgggcgatga ggttgggtat ggagcaggca tcgcccctca
    30421 ccccaatggg gagagggaga aaacgagcgc aatattcaat atcgagcaca atcggtcccc
    30481 tcgcccctct ggggagaggg ttagggtgag ggggccagcg cgcacattcc ctctcatcac
    30541 gccaccccaa tctccatccc atcaaacccc acctcaaacc ctgacggtag tgcgttttcc
    30601 atcagccacg catcaaactg gtggctgata tgggtcagaa tcacccgtgg cgagcggata
    30661 acctgattca gcgcaagcac ggtatttaaa tcacagtgat tacgcggtgc atccgcgcgc
    30721 ggcgggtgac tgcaatccat caccattacc tgcggctgat tattgcgtaa aaatttcagc
    30781 gttttttccg gcaagcctgc ggtgtcagac agccatgcca cccggctgtg tgccgtttcc
    30841 agcagataac cgaaggtcag ttttgagtgg ttgagcggca ggggcgtgac ctgtaacccc
    30901 tgcaaatcaa acaccacaaa cggttccacc gtgtggctga aatcaagcag gcccggatgt
    30961 ttaaacagat cgtcgcagcc ctgttcatcc ggcgggccgt aaaccgggat cggatcgcca
    31021 acgccccagc gcagcggaaa cagcccctgg acgtgatcca tatgataatg cgtcagcaaa
    31081 aactgctgga acgatccggg cgaccagcga tcggcgagat cgtgcagccc ggcgtcgatc
    31141 agggtgattg cgtcgttaaa cttcactacg ccgctgcacg gttggcggcg atactgcggc
    31201 gagcgccgcg ctctggcgca ggccgcacac tcgcagcccc atgccggaac gccctgtgcg
    31261 ccgccggtgc cggtgagcgt gagggtcagg ctcatgttac agcgccttgg tgaagcggaa
    31321 gtggctctgc tcgtagcctt cgcgcagata gaaacggtgc gcgtcgtggc gcttcacgtt
    31381 ggtcgaaagt tcggtcattt cggccccggc ctggcgggct tcttcttctg cccacgccag
    31441 taacttactg ccgacgttca gaccgcgcgc ctgcggcatt accaccaact cctgaatttc
    31501 gccgatccag ttgacatgat gcagatgaaa ctgcaaatgc aggccgatca tgccgacaac
    31561 ttcgccatca agcagcgcca gatggtagcg catgtttggg tcgcgcagat tggcgttaaa
    31621 acccacgcga aacgcgtggt ggtcaaactc cgcctgtttt agctcacaaa tcagcgcgta
    31681 aaccgcgtcg gtgtcgtact gcgtggccgg gcgaagctca caagcaggca tggtgtttct
    31741 ccttctgatg gatcagcgtc agcagcgtgt cgaccgactg gcgcaggctg ccgtcattgt
    31801 tgagcgtatg gcaatcctgt ggagtatagc gggcggcgcg cgccaggcgg gcgttaattt
    31861 cactggcgtt ttcacggcca cggttttcca ggcgctggcg gaggatctcc ggcgaaacct
    31921 gtaaacagac gggcagcagc gccgattgat agcgcgcccg cgcctgcggc agatgggcgc
    31981 gtgagccgtt gaccagcacg tcgaatccgg cgtgcagcca gagatcaatc tcgacgccga
    32041 cgccataata cagaccgtta gcgtgccagc ttaaggccaa cagattttgc cccgcgcggg
    32101 taaaaaactc ctgctcgctc agggcgatat ggttttcact tccggcgctg gcatcgcgcg
    32161 tgatgtagcg atgcgccacc agtaactgag tttgttcccg caggcggagt tccgccagca
    32221 ggctgtcttt cccggagccg gacggcccca ttaaccaaat cagttttccc atcatcagaa
    32281 caccctttta ccctgacgcc agacgtggtc gatatgaata tgattgtcct tgcgatgcgc
    32341 cagcaccagg tcggcgcgtt tgccctcgcc aatcaccccg cgatcctgga gattaagcgc
    32401 ctgcgctgga tttttagtca ccagcttcac cgcctgcggc agcgtaaagc ggttgctctg
    32461 gtcatcggcg acgcgaaatg ccgcatcgag caggctggcg gggtagtagt cggaagagag
    32521 gatatccagc aggccaagct gcgccagttc actggccgcc acgttgccgg agtgcgagcc
    32581 gccgcgcaca atattcggcg cgcccatcag cacgttcatg ccatgcttgc gcgaggcttc
    32641 cgccgcttcg aacgtggtgg gaaattcggc gatcacgctg ccaagctggt gagattcagc
    32701 aacgtgggcg tgggtggcgt catcgtggct ggcaagcgca atttttcgcg cgcggcacag
    32761 ggcggcgatg gattcgcgat tcggctgcga ccagcgtgcg gcgagcgcca gttgctcttc
    32821 ttcgtactgc tgcatctgcg catcagtgag ggagtatttg ccctgataat attcgcgata
    32881 cttctcgcgg ttggcgaact ggcgctggcc cggcgagtgg tccatcagcg acaccagcgt
    32941 caccggctcg cgctgcacca gtttttcaaa cagcggcagc gtggtgtgat gcggcagttc
    33001 gcagcgcaga tgcagacggt gctcggcgcg gttgacgccg cgtttctgcg tctcttcgat
    33061 ggcgttgatc atcttctcca gattctccag ccgatcgccg ccgtcgcgca cgtcgccaat
    33121 tgccacggca tccagtacgg tggtgatgcc gctcgccacc atcagcgcgt cgtggctgct
    33181 catcgccgag tgggcaggcc agtcaacttt cgggcgcggg gtgaagaatt tatccagatt
    33241 atcggtatgc agctcaatca gccccggcag cagccagccg ccttcgccgt ccatcgcctc
    33301 cggcaggcgg ctctggcttt cggcaaaggc gcggatttcg ccgttctgca cctccagcga
    33361 accgcttacc acctcgtttt ccagcaccag cttaacgtta ttgataatca tgaagaggct
    33421 cccattgggt gcaggcggtc ggcgacgtca ttacgtacag cttcgtcatg gaagatgcct
    33481 acgatggctg cgccacgggt tttggcttcg cgaatcagtt ccaccaccgc ggcgctgttt
    33541 ttggcgtcca gcgaggcggt aggttcgtca agcagcagaa tggggtagtc gacgataaag
    33601 ccgcgggcga tgttgacgcg ctgctgttcg ccaccggaaa atgtcgatgg tgccaggtgc
    33661 cacaggcgtt ccggcacgtt caggcgggtg agaagacgcg cggctttagc ggcgcaggct
    33721 tcacgcggaa cgccggtatc gagcagcggc tgcatcacca cttccagtgc tgagatacgc
    33781 gggatgacgc gcagaaactg gctcacccag ccgacggtgg ttttgcggat ttccaccact
    33841 ttgcgcgctg gcgcggtgac caggtctacc cactcgtcac cgtgtttgat ctggatttga
    33901 ccttcgtcgg gcagatagtt ggcgtacagc gagcgtagca gagttgattt gccgctgccg
    33961 gaatggccgt ggagcaccac gcattcgccc gcgttgacgg tgagcgaggc gcgattgagg
    34021 acgggcaggc gcacgccgtt ttgctggtgc aggatgaagg ttttactgac gttttgtacg
    34081 ttaatcattt ttcgcctcgt ggttcgggtg tcggatgcga cgctgacgcg tcttatccga
    34141 cctacgggga gcgcatttgt aggccggata aggcgtttac gccgcatccg gcaccggctc
    34201 aattctgcaa aaccgatgac accagcagct gtgtatacgg atgatgcggg tcgtcgagca
    34261 cgcggtcggt taacccactc tccaccactt gcccctgctt catcaccagc aaacggtccg
    34321 ccagcaggcg ggcgacgcct aaatcatggg tgacaatcac caccgcgagg ttcagctcca
    34381 ccaccaggcc gcgcagcagg tcgagcaggc gggcctgcac cgacacatcc agcccgccgg
    34441 tcggttcatc cataaacacc agcttcggat gcgtcaccag gttgcgggca atctgcaaac
    34501 gctgctgcat accgccggaa aaggtggtcg gcaggtcgtc gatccggttg gcgggaatct
    34561 ccacctcttc cagccacttc tgcgcggtgg cacgaatatc gccgtaatga cgtgccccgg
    34621 tcgccatcag ccgctcgccg atattgccgc ctgccgacac ctggcggcgc aggccgtcga
    34681 gtggatgctg atgcaccacg ccccattcgg tacgcagcag gcgacggcgg tcggcctcgc
    34741 tcattgcata cagcgaacgg ttctcgtagt gaatttcccc ctgctgcggc gtcaggcgcg
    34801 cggagatcga cttcagcagc gtggtcttcc cggagccgga ttccccgaca atgcccagca
    34861 cttcccccgg ccataaatca aaagagacat cgctaaagcc tttgcccggc gcgtaaaggt
    34921 gggtcaggtt attgaccgaa agtaacggtt gattcattgg ttttttgcct cgctctgttg
    34981 gcggcaataa tcggtatcgg agcagacaaa catgcggttt ccggcgtcat ccagcaccac
    35041 ttcatcaaga tagctgtggg tcgatccgca gatggcgcat ggctcatccc actgctgaac
    35101 ggtgaacggg tgatcgtcga aatcgagact ttccacgcgg gtaaacggcg gcaccgcata
    35161 gatgcgcttc tcgcgccccg cgccgaacag ttgcagggcg ggcatcatgt ccatttttgg
    35221 gttatcgaat ttcgggatcg gcgacgggtc catcacgtag cgcccattta ccttcaccgg
    35281 ataggcgtag gtggtggcga tatgaccgaa gcgggcgata tcttcataca gtttcacctg
    35341 catcacgccg tactcttcca gcgcgtgcat ggtgcgggtt tccgtttcgc gcggctcgat
    35401 aaagcgcagc ggctcgggga ttggcacctg gaagataatt atctgatctt cggtcagcgg
    35461 cgtttcgggg atgcggtgac gcgtctggat aaccgtcgca tcgtccgtac gttccgtggt
    35521 gtttaccccg gtcacgcgct tgaagaagtt gcgaatcgac acggcgttgg tggtgtcatc
    35581 cgcgtcctgg tcaatcacct tcagcacgtc gctttcgcca atcacgctgg cggtaagctg
    35641 aatgccgccg gttccccagc cgtacggcat cggcatctcg cgcccgccaa acggcacctg
    35701 ataaccgggg atcgccaccg cttttaagat ggcgcggcgg atcatgcgtt tggtctgctc
    35761 gtcgaggtag gcaaagttgt agccgctcag attagccatg gttctgctcc tgttgcagac
    35821 gtttgagtag ctccagttcg gcctggaaat cgacgtagtg ggggagtttg aggtgtgaga
    35881 caaagcctgc ggcttcgacg ttgtcggcat gtgccagcac gaactcttca tcctgcgccg
    35941 ggcctgtcgc gtgctcgccg tactccgggg cttgcagagc gcggtcgacc agcgccatcg
    36001 ccatcgcttt gcgctcgctc atgccgaaca ccagcccgta gccgcgcgtg aagtgcggcg
    36061 gctcacccgg cgggtcgata aaaccgttaa ccatttcaca ctcagtcatc agcagttcgc
    36121 cgacgttcac cgcaaatccc agctcttccg gcacaatcga cacgtcgata tagccgctgc
    36181 ggatctcgcc tgcgaacggg tgattgcgcc cgtaaccgcg ttgggtggag taggccagcg
    36241 ccagcaaata gccttcgtcg ccgcgcatca actgctgcaa acgggaggag cgtgagcagg
    36301 ggtaaaccgg cggcgtgcgg gtgatgtcat ccggctgtgc gccgctatcc tcttcaaact
    36361 tcgccagccc ctgacgcgcc agcaggctga aaacgtgcgg cgacggctgc tgttcgctgt
    36421 cggcggtggt cagcgtcggc gcttcgccgt ttgccagcag ggtaaaatcg agcaggcgat
    36481 gggtgtagtc gtaggttggg ccaagcagct ggccgccggg aatgtcttta taaacggcgg
    36541 agatacggcg ttcgagacgc atcccggtgg tgtcgagcgg ctcgcttacc gccagcttcg
    36601 ccaacgtggt gcggtaggcg cgcagcagga aaatcgcttc aacgttatcg ccgctggcct
    36661 gtttcagcgc cagcgccgcc agttcgcggt cggcaatgcc gccttcggtc atcacgcgat
    36721 ctaccgcgag gttaagctgc tgttcaatct gggcgacgct cagttcgggc aaatcggtat
    36781 cgcctcggcg tcggctctct tgcagggcgt gggcggcgtc gatcgccttc tcgccccctt
    36841 tcacggcaac gtacatcagc acacctccac atgagtggtt cgcggaatag ccagcaggcg
    36901 ctcgccacag gtcaggatca ggtcgatgcc gagcgggaac ggatgcgggc gctcggtgag
    36961 ttcgtgcaga atgcactccg gcagctgcgg agcgatcatt cgttcttcgg caatacccgc
    37021 accagtaagg cgcaacatgc gtccgccgct caggctggcg acctgtaaaa tcagcgtcgc
    37081 acccgcttcc ggcgcaacgg cggtgccggt ggaaagggcg ttgagctgtt cgctggaaat
    37141 cgcctcatcc gtcaccgcga aggtcgcctg ttccggctgg ctgaccagcg gcgcgttggt
    37201 atgaaaacgc aggctctggt tgacgatatc gttatttaat ggggtagaaa gccacaccgg
    37261 cgtgtcgtta tcggccagcg tcagcagcac gctggtggtg gcgatattca gcggttgcca
    37321 gccgcgtttg agctgatgca gggcgacaat cacgcccggc tcgctcatgg cctttaacag
    37381 gcgacgaaaa ctgtgctggg catcctgcac gggaagcata aaagcggttt ccagggtcat
    37441 gcgttgtctc cgcgaaccat cgtaaagaag tcgacccggc tggcgttcac ttcggcctgg
    37501 cgtgcggcaa tgcgtgccat acggtcagcg tccagcgggg caataagggt ttctgataag
    37561 ttttgaaagt ggcgagattg ctgcatcagc gcgtcaatca gcgcgcagcg ttcggcgtgc
    37621 tgtttatcac gcccctgcac ccagctgtag ccgagcgtgc cgtcagtcag gcgcacggcg
    37681 gcgcgggtca gcgtggcgtc gccggcaaaa aaacgttcgc cggtgccgcc cattcgcgcc
    37741 tgaatctgta ccaggccagt ttcagcggcg cggatcacct catagtcggc ggtgatgttt
    37801 agcgcgttca ggcgtgctgc cagttcagcc ggttggctgt gcgccagcac ggacatccag
    37861 tgctggcggg tcgcggtatc tgcgtgcatt cagtgctcca tagtgaattc aatcatgtcg
    37921 gcgcgcgtca ggctgacgga gtactccgcc gggctgcttt caccgtcacg gtggttaagg
    37981 gtgcgcacgc acagcagcgg cgacatattc gggatttcaa gacgctggca ctctttggcc
    38041 tgggcgcggc gggcgctgat ccgcgtctgg ctgcggcgca gcgcaattcc ggtttgctcg
    38101 cgcagaaaat cgtgcagcga gccgctgtcg aagcgttgca gcgtcggcca gagggtgagg
    38161 tccgcgaagt agtggtcgat taaacagagc gcgacgccgt tgacacgacg cagggtgcgc
    38221 aggtggatga cgttctcccc ctcggtaatc cccagtgcgt cagcgacgtg gccggacgcg
    38281 gggcgcaata ccgaaagcag tttttcgctg gtgggatggc tgccctgatc cagcagattc
    38341 tggctaaaac gcgcctgggc gttgagcggg taatcgaacg ggcgcatcag caccagcacg
    38401 ccgacgccct gacggcgctg tacccagcct ttttccacca gttggtcgat ggcgcggcgc
    38461 agggtgtggc gattcacctc aaagcgcgct gccagttgct gctcggcggg aagatagtcg
    38521 ccgcagcggt agtgttgacg aagctcctgc tcaagttttg cggctatctc ttgatagcgt
    38581 gttgggtagc tggtcggatg tgtagacaag tgcatagata tcaatgcctc gcttatcaga
    38641 taaagtgctt acgcaaccgt tgagagagga aatccagcag gctgaccgtg acgatgataa
    38701 gcaccatcag ggcgcaggtt tgttggaact ggaaaccgcg aatcgcttcc cacagggtga
    38761 cgccgatccc gcctgcgccg accatgccga cgacggtcgc cgagcggacg ttggattcga
    38821 agcgatagag ggagtaggag atcagcagtg gcatcacctg tggcagcacg ccgtagagga
    38881 tctcttcgag cttgttggca ccggtggcgc gaatgccttc caccgggccg ggttcaatcg
    38941 cttccaccgc ttcggaaagc agcttggaga gcacgccggt ggtgtggata aacagcgcca
    39001 gcacgccagc acgccagcga acgggccgag gccgacggcg accacgaaca gcatggcgaa
    39061 gaccatttcg ttaatggcgc ggcaggcgtc catcaggcgg cgaacgggct ggtaaaccca
    39121 ccacggcacc aggttttcgg cgctcatcag gccaaagggg atggagagaa ccaccgccag
    39181 cgcggtgccc cagacggcga tttgcagcgt gacggccatt tcggtgaggt aatcctgcca
    39241 ctggctgaaa tcgggcggga agaagtcggc ggcgaacgtc gctatgttgc cgccgtcttt
    39301 gatcagcgta agcggggcca tttccgcgcc ctgccacgag acgaccaaca cggcgagtac
    39361 aacggcccag ctcagaagcg agaaccagct gcgcttgggt ggggcgatgg tgatggtttg
    39421 catgtttggc tccggtctgt aggccggata aggtgcttgc accgcatccg gcatcaacgc
    39481 ctgcacattg tcggatgcga cgccggggcg tcttatccga cctacgattt actgcaccgc
    39541 tttactcacc gaactcatcg cgcttagcgc gttgttcagg cggtccaggt catccagctg
    39601 cgcctgaatc tcggtggttt ttgccagctt gtcctgctca ttcagtcctt tattgctttt
    39661 cacgccctgc atctctttaa acagcgcgag ctggcgaatc ggcaccagtt gcaggtcgct
    39721 ggaagcgcgg aatggcgccc agcccaggcg ttccagcacc gctttttctt ccggcgtttt
    39781 gccgtagttc ataaagaagt cgtagatctt gtctttggtg gtttcggaaa gattcttgcg
    39841 ccagacgatc ggatcgcctg ggatcagcgg cgacttccag atcaccttca gttctttcag
    39901 cttctctggc gcggaggttt tcagcttgtc gaggttttcg gtgttgttgg tggcaacatc
    39961 cacctgcttg ttggcgacgg ccagcgcgtt ggtttcatgc ccggcgttga cggtgcgctt
    40021 gaagtcgctg gcggagatat tgtttttggc gaagacgtag tagccgggga cgaggaagcc
    40081 agaggtggag ttaggatcgc cattgccaaa ggtgagatct ttccgcttcg ccagcagatc
    40141 gttcaggttg ttgatcggac tgtctttgtt gacgatcaac acgctccagt aacccggcga
    40201 tccatccgcc gcgaccgtct gggcgaagac ctggccattg gcgcgatcca ccgcttccat
    40261 cgccgacaga ttgccgtacc aggcgatatc cactttattg aagcgcatcc cctggataat
    40321 gcccgcgtag tccggggcaa agaaggcgtt gaccttcacg cccagcttct tctccatatc
    40381 ctgcaagaac ggcgtccatt gcggtttcag gttttgctgt gattccgttg aaataatgcc
    40441 gaaattcaac gccttttcct gctcttcggc gtgcgccggg cttaacaggg tgctgaggct
    40501 gaacatgctg gtgaaggcca gcgaggcaat tatcttagcg ttcattcgtt ttcctcaatg
    40561 atggggatgt caggcagctt tcgcgttctc ttcgacgcgg ttaatgctgc ggtagagatg
    40621 gtcaaaacgt tcgttatcaa actgttggct gctgccgtcg tagaagacgt gcccctggcg
    40681 cagggcgacg atgcgttcgc agtagcgcag ggcgtaatcc acctgatgca gcgtgacgac
    40741 cacggtgatg ccgtcgttct ggttgatgtc gcgcagggtg tccatcacga tgcgcgctga
    40801 ttctgggtcc agcgaggcga tgggttcatc ggccagaatc actttcgcct gctgcatcag
    40861 cgcacgggca atcgccacac gttgctgctg gccgccggag agggtggaaa cgcgctgatg
    40921 ggcaaaatgc accatgccaa cgcgggtcag cgcctgtaac gcgcgctgtt tctgctcgcc
    40981 ggtgaaccag ctaaaacagg tgcgccagaa cggcgtgctg ccgagcgcgc caatcagcac
    41041 gttctccagt acgctcaggc ggttcaccag gttgaattgt tggaatatgt agccggtatg
    41101 ggcgcggctt ttgcggatat cgcgggccag gcggccttcg cgctggactg tgcggcccag
    41161 cagctcgata tggctaccga cagatttatc gccggtaatc aaaccgctta agtgacgtaa
    41221 aagggtggat tttccggaac ccgacggccc aagcagagcc accatttcac cgtgatgaat
    41281 gttcagatca accgcatgca gcgcctgatg ctgattgaag gttttggcga gcttctcgac
    41341 acggataatc gtttgcatga tgcagcctcc ctaaaaaagt ggctccatcg tggcggatta
    41401 ttgtgacgat ttggttaatt aaaagtgact aacagatgaa gagttaacgg gaattcgatg
    41461 acagtgcggg agggcgggcc tcccggcggg ttattgcgtt ggttgttgtt tgacgacatt
    41521 aatcatccac ggtacgccaa atttatcggt gactttgcca aagccatgcg cccagaaagt
    41581 ttcctgccag gccatttcga tttttccgtt agcggcaaga ttgtcaaact agcgttttcc
    41641 ttcttcgacc tgttgcgaat cgagcaccag cgtaaagccg gagtagctgg cttttcctga
    41701 cggcatggca tcgctcatca tgatgtcgct tccggcaatg cgcacattgg cgtgggcgat
    41761 ggcggtatcg ggaaattgca ttccggaagg gcagttctcg gcgctgtcct gcgctgattt
    41821 tggcatttcg ccgaagctga ttttatagag cagttccgcg cccaacgtac gttgataata
    41881 ggcaatcgcg tcggaacagt taccggcaaa agagaggtag ggacttaacg gcatgatggt
    41941 gacctcagtt aagagaagcc agttaagtgt agttcgaaat ttatacagat gagaggcggc
    42001 ctgataagac gcgcgagcgt cgcatcaggc agtcggcact gttgccggat gcggcgtaaa
    42061 cgccttatcc ggcctacgga gggtgcggga atttgtaggc ctgataagac gcgcaagcgt
    42121 cgcatcaggc agtcggcacc
//
LOCUS       DAPOAV010000034        41700 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.034, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000034 DAPOAV010000000
VERSION     DAPOAV010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 41700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41700
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.034"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            28..450
                     /locus_tag="RN951_002088"
     CDS             28..450
                     /locus_tag="RN951_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527087.1"
                     /translation="MTRVVIALLFLAGCTSQMKYSNVVRIRNVCSSDINVFIPEYVFG
                     GNVIKQHHIYLPVNGIDVLSYFYTENINDGFQYEEAFTVNKDSSGNFDYPFVILSSGR
                     EKKFGKNDLIELSRDISTKDDKKHGVVKYMIDSQDICP"
     gene            1010..2770
                     /gene="tssF"
                     /locus_tag="RN951_002089"
     CDS             1010..2770
                     /gene="tssF"
                     /locus_tag="RN951_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssF"
                     /protein_id="HDX2527088.1"
                     /translation="MDDLTQRYYEAEMRYLREAGKEFAQAYPDRAAMLNLDKPGARDP
                     YVERLFEGFAFLMGSLREKLDDDLPELTEGLVSLLWPHYLRTIPSLSVVELSTDHRQM
                     KQSETLSDFQVLSRPVGERRTRCFYSATRDITLHPLALPDVSLQYEPDGRSVIRLRFE
                     CGPLVGDWSQIDLSRLPFYLNADSPVACALHRALTLGTQQFWLRLPGQDRRTLDAHFS
                     PLGFEDNDRLWPKGESAFSGYQLLLEYFTFREKFMFVALNGLELVAWPEGITGFEIDV
                     VLNENWPHDLPFDSDNIRLHCVPVINLFPLEADPLHLSPLENEFLLRPMRIQDGHTEI
                     YSVDNIISSRHTGSQAYVPFSSFRHRGGMLRHDAPERYYHTRVKRGPSGLHDTWLILG
                     GDAFDADRMLEDETLSLSLTGTNGHLPRKALQSTLLDRPVHASQNVLRVRNLCAPTQP
                     CYPPARDRFHWRVLSHLGSNFLSMMDNAEILRGTLALYDWTESEMNRRRLEAIVDVQH
                     SLIQRFERGFLLRGVDIQVTLDSNGFAGEGDITLFGELLHRFFALYADIHLFTQLTLI
                     LQPTGKCLQWTEHHSQRVPG"
     gene            2734..3813
                     /gene="tssG"
                     /locus_tag="RN951_002090"
     CDS             2734..3813
                     /gene="tssG"
                     /locus_tag="RN951_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssG"
                     /protein_id="HDX2527089.1"
                     /translation="MDRASQPARTGLTDRLAPDIARINFYRFCQLLEQSQQNAPLGST
                     DNPATDAVRFRPHPGMGFPVSELKNVERDAGNPDVPPTVRTTFLGLYGVDSPLPTAYL
                     DYITQRHDGHDAVMAFLDIFNHRFITQYYRIWRKYNYPASFEAGAMDDISRCLLGLIG
                     LGIPGSENHIATPVSRFLALLSVMRLPTRTAEGVTALVGLLAPLTKATVVPHDPQPVI
                     LPAPAGLSKNSRISLKTRTLLGRTGTDVNSQLLLKLYTEDAAEARGWLPGGQLHSDLL
                     VLLRVYLGWRCQARLQLTLPVSLLPAARLGKQRVQISRTGILRASFAAPATGTVTVSL
                     GRYQGLIPALSIRNRESMTHVSYSF"
     gene            3794..4330
                     /gene="tssJ"
                     /locus_tag="RN951_002091"
     CDS             3794..4330
                     /gene="tssJ"
                     /locus_tag="RN951_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system lipoprotein TssJ"
                     /protein_id="HDX2527090.1"
                     /translation="MFPIRFKRPALLCMAMLTVVLSGCGLIQKVVDESKSVASAVFYK
                     QIKILHLDFFSRSALNTDAEDTPLSTMVHVWQLKTREDFDKADYDTLFMQEEKTLEKD
                     VLAKHTVWVKPEGTASLNVPLDKETQFVAIIGQFYHPDEKSDSWRLVIKRDELEADKP
                     RSIELMRSDLRLLPLKDK"
     gene            4334..4762
                     /gene="tssE"
                     /locus_tag="RN951_002092"
     CDS             4334..4762
                     /gene="tssE"
                     /locus_tag="RN951_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000106970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssE"
                     /protein_id="HDX2527091.1"
                     /translation="MSTPSLYEMLTFSFSGELPLEQVSERDQLILSVMDNMQRIINCR
                     AGTLAHLPDYGLPDLSLIHQGMVAGIHGLMRQIEETLLRYEPRLSQIQVELLPQPRPG
                     YLNYLIHAQLPDTGWIRFDGVFSPEGRIVLRHLKQQERAY"
     gene            4762..6138
                     /locus_tag="RN951_002093"
     CDS             4762..6138
                     /locus_tag="RN951_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system ImpA family N-terminal
                     domain-containing protein"
                     /protein_id="HDX2527092.1"
                     /translation="MASNANFISQFVMGGDPCTYKESGELQAEMSKLTHPARPDVDWR
                     RVEKLSLALFRQNGVELQTQVCYVLAITRRQGLAGMADGLGSLDILLQRWADFWPVQV
                     HSRISLLSWVTEKMQQALRTLDIQYQDLPQIYRCVQHLSAIETTLQQCELWHMTKLDV
                     LAGQFRNTALRLERLAPQGAETTITPPELPRREMKQPEKSEESPQPVFATRPAQQNDK
                     DASPSAPSPEISRQRTWPIFMAGMVVMACLGGTGLWGWSQLNQPDALIQRIQLSVMPL
                     PQSLESGELAKLDVKDKALLAQDRTIAASQMQLEQLNKLPARWPLEQGYRQLRQLDAL
                     WPDNPQVRALNAQWRKQRELSALSTEALNGYAQAQSQLQRLSAQLDALDERKGRYLTG
                     SELKTAVYGIRQSLKEPPLEELLRQLEEQKQTGEVSPTLLTQIDTRLNQLLNRYVILL
                     DTKVEQSQ"
     gene            6203..6751
                     /locus_tag="RN951_002094"
     CDS             6203..6751
                     /locus_tag="RN951_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucR family transcriptional regulator"
                     /protein_id="HDX2527093.1"
                     /translation="MYKKERNRPFETREEVLAYHKREKIPCLECGKLLIFLPRHIWFV
                     HGIRADEYRVKWNIPKHIALAGISYLEKQSEYMKARIAKGKLDPAEQIAMMRIKGRQL
                     KSDPDWRNRSGSILKKQYARRDILKNRVWERSPSIKSVSVELKTEAIRRMKNRKVVGE
                     KVQDIADDLNVSISRLYHWLKM"
     gene            complement(7097..8350)
                     /gene="amiC"
                     /locus_tag="RN951_002095"
     CDS             complement(7097..8350)
                     /gene="amiC"
                     /locus_tag="RN951_002095"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311701.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiC"
                     /protein_id="HDX2527094.1"
                     /translation="MSGSNTAISRRRLLQGAGAMWLLSVSQVSLAAVSQVVAVRVWPA
                     SSYTRVTVESNRQLKYKQFALSNPERVVVDIEDVNLNSVLKGMAAQIRADDPFIKSAR
                     VGQFDPQTVRMVFELKQNVKPQLFALAPVAGFKERLVMDLYPANAQDMQDPLLALLED
                     YNKGDLEKQVPPAQSGPQPGKAGRDRPIVIMLDPGHGGEDSGAVGKYKTREKDVVLQI
                     ARRLRSLIEKEGNMKVYMTRNEDIFIPLQVRVAKAQKQRADLFVSIHADAFTSRQPSG
                     SSVFALSTKGATSTAAKYLAQTQNASDLIGGVSKSGDRYVDHTMFDMVQSLTIADSLK
                     FGKAVLNKLGKINKLHKNQVEQAGFAVLKAPDIPSILVETAFISNVEEERKLKTATFQ
                     QEVAESILAGIKAYFADGATLARRG"
     gene            8582..9913
                     /gene="argA"
                     /locus_tag="RN951_002096"
     CDS             8582..9913
                     /gene="argA"
                     /locus_tag="RN951_002096"
                     /EC_number="2.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino-acid N-acetyltransferase"
                     /protein_id="HDX2527095.1"
                     /translation="MVKERKTELVEGFRHSVPYINTHRGKTFVIMLGGEAIEHENFSS
                     IVNDIGLLHSLGIRLVVVYGARPQIDANLAAHHHEPLYHKNIRVTDAKTLELVKQAAG
                     TLQLDITARLSMSLNNTPLQGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEDA
                     IHRQLDSGAIVLMGPVAVSVTGESFNLTSEEIATQLAIKLKAEKMIGFCSSQGVTNDD
                     GDIVSELFPNEAQARVEAQEEKGDYNSGTVRFLRGAVKACRSGVRRCHLISYQEDGAL
                     LQELFSRDGIGTQIVMESAEQIRRATINDIGGILELIRPLEQQGILVRRSREQLEMEI
                     DKFTIIQRDNTTIACAALYPFPEEKIGEMACVAVHPDYRSSSRGEVLLERIAAQAKQS
                     GLSKLFVLTTRSIHWFQERGFTPVDIDLLPESKKQLYNYQRKSKVLMADLG"
     gene            complement(9975..11801)
                     /gene="recD"
                     /locus_tag="RN951_002097"
     CDS             complement(9975..11801)
                     /gene="recD"
                     /locus_tag="RN951_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit alpha"
                     /protein_id="HDX2527096.1"
                     /translation="MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSH
                     DAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMIL
                     CGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAV
                     ALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGK
                     ALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDL
                     PMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERAGQLSRLTG
                     THVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTD
                     IEKRLLQSGEDYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFG
                     VAGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGT
                     RVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELV
                     YTAVTRARRRLSLYADERILSAAIATRTERRSGLAALFSSRE"
     gene            complement(11801..15343)
                     /gene="recB"
                     /locus_tag="RN951_002098"
     CDS             complement(11801..15343)
                     /gene="recB"
                     /locus_tag="RN951_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708611.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit beta"
                     /protein_id="HDX2527097.1"
                     /translation="MSDVAETLDPLRLPLQGERLIEASAGTGKTFTIAALYLRLLLGL
                     GGSAAFPRPLTVEELLVVTFTEAATAELRGRIRSNIHELRIACLRETTDNPLYERLLE
                     EIDDKAQAAQWLLLAERQMDEAAVFTIHGFCQRMLNLNAFESGMLFEQQLIEDESLLR
                     YQACADFWRRHCYPLPREIALVVFETWKGPQALLRDINRYLQGEAPVIKAPPPDDETL
                     ASRHAQIVARIDTVKQQWRDAVGELDALIESSGIDRRKFNRSNQAKWIEKISAWAEEE
                     TNSYQLPESLEKFSQRFLEDRTKAGGETPRHPLFEAIDQLLAEPLSIRDLVITRALAE
                     IRETVAREKRRRGELGFDDMLSRLDSALRSESGEVLAAAIRTRFPVAMIDEFQDTDPQ
                     QYRIFRRIWHHQPETALLLIGDPKQAIYAFRGADIFTYMKARSEVHAHYTLDTNWRSA
                     PGMVNSVNKLFSQTDDAFMFREIPFIPVKSAGKNQALRFVFKGETQPAMKMWLMEGES
                     CGVGDYQSTMAQVCAAQIRDWLQAGQRGEALLMNGDDARPVRASDISVLVRSRQEAAQ
                     VRDALTLLEIPSVYLSNRDSVFETLEAQEMLWLLQAVMTPERENTLRSALATSMMGLN
                     ALDIETLNNDEHAWDAVVEEFDGYRQIWRKRGVMPMLRALMSARNIAENLLATAGGER
                     RLTDILHISELLQEAGTQLESEHALVRWLSQHILEPDSNASSQQMRLESDKHLVQIVT
                     IHKSKGLEYPLVWLPFITNFRVQDQAFYHDRHSFEAVLDLNAAPESVDLAEAERLAED
                     LRLLYVALTRSVWHCSLGVAPLVRRRGDKKGDTDVHQSALGRLLQKGEPQDAAGLRTC
                     IEALCDDDIAWQTAQTGDKQPWQVNDALTAELNARTLQRLPGDNWRVTSYSGLQQRGH
                     GIAQDLMPRLDVDAAGVVSVVEEPTLTPHQFPRGASPGTFLHSLFEDLDFTQPVDPNW
                     VQEKLELGGFESQWEPVLTEWITAVLQAPLNETGVSLNQLSDRDKQVEMEFYLPISEP
                     LIASQLDALIRQFDPLSAGCPPLEFMQVRGMLKGFIDLVFRHEGRYYLLDYKSNWLGE
                     DSSAYTQQAMAAAMQAHRYDLQYQLYTLALHRYLRHRIADYDYDRHFGGVIYLFLRGV
                     DKEHPQQGIYTTRPNAGLIALMDEMFAGMTLEEA"
     gene            complement(15336..18224)
                     /gene="ptrA"
                     /locus_tag="RN951_002099"
     CDS             complement(15336..18224)
                     /gene="ptrA"
                     /locus_tag="RN951_002099"
                     /EC_number="3.4.24.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pitrilysin"
                     /protein_id="HDX2527098.1"
                     /translation="MPRSTWFKALLLLVALWAPLSQAETGWQPIQETIRKSDKDNRQY
                     QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYP
                     QADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAE
                     RERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQAL
                     KDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKG
                     IIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTLSDWLQKQGLVE
                     GISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKGIDKQYFDEL
                     ANVLDIDFRYPSITRDMDYVEWLADTMIRVPVEHTLDAVNIADRYDAKAVKERLAMMT
                     PQNARIWYISPKEPHNKTAYFVDAPYQVDKISAQTFADWQKKAADIALSLPELNPYIP
                     DAFSLIKSEKKYDHPELIVDESNLRVVYAPSRYFASEPKADVSLILRNPKAMDSARNQ
                     VMFALNDYLAGLALDQLSNQASVGGISFSTNANNGLMVNANGYTQRLPQLFQALLEGY
                     FSYTATEDQLEQAKSWYNQMMDSAEKGKAFEQAIMPAQMLSQVPYFSRDERRKILPSI
                     TLKEVLAYRDALKSGARPEFMVIGNMTEDQATTLARDVQKQLGADGSEWCRNKDVVVD
                     KKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLG
                     YAVFAFPMSVGRQWGMGFLLQSNDKQPSFLWERYKAFFPTAEAKLRAMKPEEFAQIQQ
                     AVITQMLQAPQTLGEEASKLSKDFDRGNMRFDSRDKIVAQIKLLTPQKLADFFHQAVV
                     EPQGMAILSQISGSQNGKAEYVHPEGWKVWENVSALQQTMPLMSEKNE"
     gene            complement(18399..21767)
                     /gene="recC"
                     /locus_tag="RN951_002100"
     CDS             complement(18399..21767)
                     /gene="recC"
                     /locus_tag="RN951_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit gamma"
                     /protein_id="HDX2527099.1"
                     /translation="MLRVYHSNRLDVLEALMEFIVERERLDDPFEPEMILVQSTGMAQ
                     WLQMTLSQKFGIAANIDFPLPASFIWDMFVRVLPEIPKESAFNKQSMSWKLMTLLPQL
                     LDREDFTLLRHYLTDDSDKRKLFQLSSKAADLFDQYLVYRPEWLAQWETGHLVEGLGE
                     AQAWQAPLWKALVEYTHQLGQPRWHRANLYQRFIETLESATTCPPGLPSRVFICGISA
                     LPPVYLQALQALGKHIEIHLLFTNPCRYYWGDIKDPAYLAKLLTRQRRHSFEDRELPL
                     FRDSENAGQLFNSDGEQDVGNPLLASWGKLGRDYIYLLSDLESSQELDAFVDVMPDNL
                     LHNIQSDILELENRAVAGVNIEEFSRSDNKRPLDPLDSSITFHVCHSPQREVEVLHDR
                     LLAMLEEDPTLTPRDIIVMVADIDSYSPFIQAVFGSAPADRYLPYAISDRRARQSHPV
                     LEAFISLLSLPDSRFVSEDVLALLDVPVLAARFDITEEGLRYLRQWVNESGIRWGIDD
                     DNVRELELPATGQHTWRFGLTRMLLGYAMESAQGEWQSVLPYDESSGLIAELVGHLAS
                     LLMQLNIWRRGLAQERPLEEWLPVCRDMLNAFFLPDAETEAAMTLIEQQWQAIIAEGL
                     GAQYGDAVPLSLLRDELAQRLDQERISQRFLAGPVNICTLMPMRSIPFKVVCLLGMND
                     GVYPRQLAPLGFDLMSQKPKRGDRSRRDDDRYLFLEALISAQQKLYISYIGRSIQDNS
                     ERFPSVLVQELIDYIGQSHYLPGDEALNCDESEARVKAHLTCLHTRMPFDPQNYQPGE
                     RQSYAREWLPAASQAGKAHSEFVQPLPFTLPETVPLETLQRFWAHPVRAFFQMRLQVN
                     FRTEDSEIPDTEPFILEGLSRYQINQQLLNALVEQDDAERLFRRFRAAGDLPYGAFGE
                     IFWETQCQEMQQLADRVIACRQPGQSMEIDLACNGVQITGWLPQVQPDGLLRWRPSLL
                     SVAQGMQLWLEHLVYCASGGNGESRLFLRKDGEWRFPPLAAEQALHYLSQLIEGYREG
                     MSAPLLVLPESGGAWLKTCYDAQNDAMLDDDSTLQKARTKFLQAYEGNMMVRGEGDDI
                     WYQRLWRQLTPETMEAIVEQSQRFLLPLFRFNQS"
     gene            complement(21780..22103)
                     /locus_tag="RN951_002101"
     CDS             complement(21780..22103)
                     /locus_tag="RN951_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDX2527100.1"
                     /translation="MSASLKNQQGFSLPEVMLAMVLMVMIVTALSGFQRTLMNSLASR
                     NQYQQLWQHGWQQTQLRAISPPANWQVNRMQTSQAGCVSISVTLVSPGGREGEMTRLH
                     CPNRQ"
     gene            complement(22088..22495)
                     /locus_tag="RN951_002102"
     CDS             complement(22088..22495)
                     /locus_tag="RN951_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417301.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2509 family protein"
                     /protein_id="HDX2527101.1"
                     /translation="MNREKGVSSLALVLMLLVLGSLLLQGMSQQDRSFASRVSMESQS
                     LRRQAIVQSALAWGKMHSWQTQPAVQCSQYAGTDAQVCLRLLADNEALLIAGYEGVSL
                     WRTGEVIDGNIVFSPRGWSDFCPLKERALCQLP"
     gene            complement(22492..23055)
                     /locus_tag="RN951_002103"
     CDS             complement(22492..23055)
                     /locus_tag="RN951_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HDX2527102.1"
                     /translation="MPVKEQGFSLLEVLIAMAISSVLLLGAARFLPALQRESLTSTRK
                     LALEDEIWLRVFTVAKHLQRAGYCHGSCTGEGLEIVGQGDCIIVQWDANSNGIWDREP
                     VKESDQIGFRLKEHVLETLRGAASCEGKGWDKVTNPDAIIIDTFQVVRQDVSGFSPVL
                     TVNMRAASKSEPQTVVDASYSVTGFNL"
     gene            complement(23046..23516)
                     /locus_tag="RN951_002104"
     CDS             complement(23046..23516)
                     /locus_tag="RN951_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HDX2527103.1"
                     /translation="MKTQRGYTLIETLVAMLILVMLSASGLYGWQYWQQSQRLWQTAS
                     QARDYLLYLREDANWHNRDHSISVIREGTLWCLVSSVAGANTCHGSSPLVFVPRWPEV
                     EMSDLTPSLAFFGLRNTAWAGHIRFKNSTGEWWLVVSPWGRLRLCQQGETEGCL"
     gene            complement(23701..24495)
                     /gene="thyA"
                     /locus_tag="RN951_002105"
     CDS             complement(23701..24495)
                     /gene="thyA"
                     /locus_tag="RN951_002105"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HDX2527104.1"
                     /translation="MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPL
                     VTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWP
                     TPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
                     CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHL
                     QLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI"
     gene            complement(24502..25377)
                     /gene="lgt"
                     /locus_tag="RN951_002106"
     CDS             complement(24502..25377)
                     /gene="lgt"
                     /locus_tag="RN951_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HDX2527105.1"
                     /translation="MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRR
                     ANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSF
                     HGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNF
                     PFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYI
                     RKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVI
                     MMVWAYRRSPQQHVS"
     gene            complement(25528..27774)
                     /gene="ptsP"
                     /locus_tag="RN951_002107"
     CDS             complement(25528..27774)
                     /gene="ptsP"
                     /locus_tag="RN951_002107"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDX2527106.1"
                     /translation="MLTRLREIVEKVASAPRLNEALNILVTDICLAMDTEVCSVYLAD
                     HDRRCYYLMATRGLKKPRGRTVTLAFDEGIVGLVGRLAEPINLADAQKHPSFKYIPSV
                     KEERFRAFLGVPIIQRRQLLGVLVVQQRELRQYDESEESFLVTLATQMAAILSQSQLT
                     ALFGQYRQTRIRALPAAPGVAIAEGWQDATLPLMEQVYQASTLDPALERERLTGALEE
                     AANEFRRYSKRFAAGAQKETAAIFDLYSHLLSDTRLRRELFAEVDKGSVAEWAVKTVI
                     EKFAEQFAALSDNYLKERAGDLRALGQRLLFHLDDANQGPNAWPERFILVADELSATT
                     LAELPQDRLVGVVVRDGAANSHAAIMVRALGIPTVMGADIQPSVLHRRTLIVDGYRGE
                     LLVDPEPVLLQEYQRLISEEIELSRLAEDDVNLPAQLKSGERIKVMLNAGLSPEHEEK
                     LGSRIDGIGLYRTEIPFMLQSGFPSEEEQVAQYQGMLQMFNDKPVTLRTLDVGADKQL
                     PYMPISEENPCLGWRGIRITLDQPEIFLIQVRAMLRANAATGNLNILLPMVTSLDEVD
                     EARRLIERAGREVEEMIGYEIPKPRIGIMLEVPSMVFMLPHLAKRVDFISVGTNDLTQ
                     YILAVDRNNTRVANIYDSLHPAMLRALAMIAREAEIHGIDLRLCGEMAGDPMCVAILI
                     GLGYRHLSMNGRSVARVKYLLRRIDYADAENLAQRSLEAQLATEVRHQVAAFMERRGM
                     GGLIRGGL"
     gene            complement(27787..28317)
                     /gene="rppH"
                     /locus_tag="RN951_002108"
     CDS             complement(27787..28317)
                     /gene="rppH"
                     /locus_tag="RN951_002108"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001655775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA pyrophosphohydrolase"
                     /protein_id="HDX2527107.1"
                     /translation="MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGE
                     SAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLL
                     QLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMSLQE
                     NTPKPQNASAYRRKRG"
     gene            29002..29691
                     /gene="mutH"
                     /locus_tag="RN951_002109"
     CDS             29002..29691
                     /gene="mutH"
                     /locus_tag="RN951_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutH"
                     /protein_id="HDX2527108.1"
                     /translation="MSQPRPLLSPPETEEQLLAQAQQLSGYTLGELAALAGLVTPENL
                     KRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTG
                     NSGVTWETSHVRHKLKRVLWIPVEGERSIPLAQRRVGSPLLWSPNEEEDRQLREDWEE
                     LMDMIVLGQVERITARHGEYLQIRPKAANAKALTEAIGARGERILTLPRGFYLKKNFT
                     SALLARHFLIQ"
     gene            29760..30473
                     /locus_tag="RN951_002110"
     CDS             29760..30473
                     /locus_tag="RN951_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HDX2527109.1"
                     /translation="MLFAWITDPNAWLALGTLTLLEIVLGIDNIIFLSLVVAKLPTAQ
                     RAHARRLGLAGAMVMRLALLASIAWVTRLTNPLFTIFSQEISARDLILLLGGLFLIWK
                     ASKEIHESIEGEEEGLKTRVSSFLGAIVQIMLLDIIFSLDSVITAVGLSDHLFIMMAA
                     VVIAVGVMMFAARSIGDFVERHPSVKMLALSFLILVGFTLILESFDIHVPKGYIYFAM
                     FFSIAVESLNLIRNKKNPL"
     gene            30611..30829
                     /gene="ygdR"
                     /locus_tag="RN951_002111"
     CDS             30611..30829
                     /gene="ygdR"
                     /locus_tag="RN951_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein YgdR"
                     /protein_id="HDX2527110.1"
                     /translation="MKKWAVIISAVGLAFAVSGCSSDYVMATKDGRMILTDGKPEIDD
                     DTGLVSYHDQQGNAMQINRDDVSQIIER"
     gene            30937..31977
                     /locus_tag="RN951_002112"
     CDS             30937..31977
                     /locus_tag="RN951_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(H)-dependent aldo-keto reductase"
                     /protein_id="HDX2527111.1"
                     /translation="MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGI
                     NLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPD
                     QALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDT
                     LDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVG
                     LAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAA
                     YVDIARRHGLDPAQMALAFVRRQPFVASTLLGATTMDQLKTNIESLHLELSEDVLAEI
                     EAVHQVYTYPAP"
     gene            complement(32009..33202)
                     /gene="lplT"
                     /locus_tag="RN951_002113"
     CDS             complement(32009..33202)
                     /gene="lplT"
                     /locus_tag="RN951_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid transporter LplT"
                     /protein_id="HDX2527112.1"
                     /translation="MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLKAQ
                     FYPEWSQPILQMVFVGAYILFAPFVGQVADSFAKGRVMMFANGLKLLGAASICFGINP
                     FLGYTLVGVGAAAYSPAKYGILGELTTGSKLVKANGLMEASTIAAILLGSVAGGVLAD
                     WHVLVALAACALAYGGAVVANIYIPKLAAARPGQSWNLINMTRSFLNACTSLWRNGET
                     RFSLVGTSLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKL
                     VTLETVSRCMPAGILIGVVVLIFSLQHELLPAYALLMLIGVMGGFFVVPLNALLQERG
                     KKSVGAGNAIAVQNLGENSAMLLMLGIYSLAVMIGIPVVPIGIGFGALFALAITALWI
                     WQRRH"
     gene            complement(33195..35354)
                     /gene="aas"
                     /locus_tag="RN951_002114"
     CDS             complement(33195..35354)
                     /gene="aas"
                     /locus_tag="RN951_002114"
                     /EC_number="2.3.1.40"
                     /EC_number="6.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acyl-ACP--phospholipid
                     O-acyltransferase/long-chain-fatty-acid--ACP ligase"
                     /protein_id="HDX2527113.1"
                     /translation="MLFSFFRNLCRVLYRVRVTGDTQALKGERVLITPNHVSFIDGIL
                     LGLFLPVRPVFAVYTSISQQWYMRWLKSFIDFVPLDPTQPMAIKHLVRLVEQGRPVVI
                     FPEGRITTTGSLMKIYDGAGFVAAKSGATVIPVRIEGAELTHFSRLKGLVKRRLFPQI
                     TLHILPPTQVAMPDAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLSAMYRFG
                     AGKKCVEDVNFTPDSYRKLLTKTLFVGRILEKYSVEGERIGLMLPNAGISAAVIFGAI
                     ARRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLE
                     DLKADVTTADKVWIFAHLLMPRLAQVKQQPEEEALILFTSGSEGHPKGVVHSHKSILA
                     NVEQIKTIADFTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPEL
                     VYDRSCTVLFGTSTFLGHYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRIL
                     EGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEGGRLQLKGPNIMNG
                     YLRVEKPGVLEVPTAENVRGEMERGWYDTGDIVRFDEQGFVQIQGRAKRFAKIAGEMV
                     SLEMVEQLALGVSPDKVHATAIKSDASKGEALVLFTTDNELTRDKLQQYAREHGVPEL
                     AVPRDIRYLKQMPLLGSGKPDFVTLKSWVDEAEQHDE"
     gene            35940..36971
                     /gene="galR"
                     /locus_tag="RN951_002115"
     CDS             35940..36971
                     /gene="galR"
                     /locus_tag="RN951_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalR"
                     /protein_id="HDX2527114.1"
                     /translation="MATIKDVARLAGVSVATVSRVINNSPKASEASRLAVHSAMESLS
                     YHPNANARALAQQTTETVGLIVGDVSDPFFGAMVKAVEQVAYHTGNFLLIGNGYHNEQ
                     KERQAIEQLIRHRCAALVVHAKMIPDADLASLMKQMPGMVLINRILPGFENRCIALDD
                     RYGAWLATRHLIQQGHTRIGYLCSNHSISDAEDRLQGYYDALAESGIAANDRLVTFGE
                     PDESGGEQAMTELLGRGRNFTAVACYNDSMAAGAMGVLNDNGIDVPGEISLIGFDDVL
                     VSRYVRPRLTTVRYPIVTMATQAAELALALADNRPLPEITNVFSPTLVRRHSVSTPSL
                     EASHHATSD"
     gene            complement(36978..38240)
                     /gene="lysA"
                     /locus_tag="RN951_002116"
     CDS             complement(36978..38240)
                     /gene="lysA"
                     /locus_tag="RN951_002116"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HDX2527115.1"
                     /translation="MPHSLFSTDTDLTAENLLRLPAEFGCPVWVYDAQIIRRQIAALK
                     QFDVVRFAQKACSNIHILRLMREQGVKVDSVSLGEIERALAAGYNPQTHPDDIVFTAD
                     VIDQATLERVSELQIPVNAGSVDMLDQLGQVSPGHRVWLRVNPGFGHGHSQKTNTGGE
                     NSKHGIWYTDLPAALDVIQRHHLQLVGIHMHIGSGVDYAHLEQVCGAMVRQVIEFGQD
                     LQAISAGGGLSVPYQQGEEAVDTEHYYGLWNAAREQIARHLGHPVKLEIEPGRFLVAQ
                     SGVLITQVRSVKQMGSRHFVLVDAGFNDLMRPAMYGSYHHISALAADGRSLEHAPTVE
                     TVVAGPLCESGDVFTQQEGGNVETRALPEVKAGDYLVLHDTGAYGASMSSNYNSRPLL
                     PEVLFDNGQARLIRRRQTIEELLALELL"
     gene            38362..39297
                     /gene="lysR"
                     /locus_tag="RN951_002117"
     CDS             38362..39297
                     /gene="lysR"
                     /locus_tag="RN951_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator LysR"
                     /protein_id="HDX2527116.1"
                     /translation="MAAVNLRHIEIFHAVMTAGSLTEAAHLLHTSQPTVSRELARFEK
                     VIGLKLFERVRGRLHPTVQGLRLFEEVQRSWYGLDRIVSAAESLREFRQGELSIACLP
                     VFSQSFLPQLLQPFLARYPDVSLNIVPQESPLLEEWLSAQRHDLGLTETLHTPAGTER
                     TELLSLDEVCVLPPGHPLAVKKVLTPDDFQGENYISLSRTDSYRQLLDQLFTEHQVKR
                     RMIVETHSAASVCAMVRAGVGVSVVNPLTALDYAASGLVVRRFSIAVPFTVSLIRPLH
                     RPSSALVQAFSEHLQAGLPKLVTSLDAILSSATTA"
     gene            complement(39284..39976)
                     /gene="ygeA"
                     /locus_tag="RN951_002118"
     CDS             complement(39284..39976)
                     /gene="ygeA"
                     /locus_tag="RN951_002118"
                     /EC_number="5.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HDX2527117.1"
                     /translation="MKTIGLLGGMSWESTIPYYRLINEGIKQRLGGLHSAQVLLHSVD
                     FHEIEECQRRGEWDKTGDILAEAALGLQRAGAEGIVLCTNTMHKVADAIESRCTLPFL
                     HIADATGRAITGAGMTRVALLGTRYTMEQDFYRGRLTEQFSINCLIPEADERAKINQI
                     IFEELCLGQFTEASRAYYAQVIARLAEQGAQGVIFGCTEIGLLVPEERSVLPVFDTAA
                     IHAEDAVAFMLS"
     gene            complement(40105..41523)
                     /gene="araE"
                     /locus_tag="RN951_002119"
     CDS             complement(40105..41523)
                     /gene="araE"
                     /locus_tag="RN951_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-proton symporter AraE"
                     /protein_id="HDX2527118.1"
                     /translation="MVTINTESALTPRSLRDTRRMNMFVSVAAAVAGLLFGLDIGVIA
                     GALPFITDHFVLTSRLQEWVVSSMMLGAAIGALFNGWLSFRLGRKYSLMAGAILFVLG
                     SIGSAFATSVEMLIAARVVLGIAVGIASYTAPLYLSEMASENVRGKMISMYQLMVTLG
                     IVLAFLSDTAFSYSGNWRAMLGVLALPAVLLIILVVFLPNSPRWLAEKGRHIEAEEVL
                     RMLRDTSEKAREELNEIRESLKLKQGGWALFKINRNVRRAVFLGMLLQAMQQFTGMNI
                     IMYYAPRIFKMAGFTTTEQQMIATLVVGLTFMFATFIAVFTVDKAGRKPALKIGFSVM
                     ALGTLVLGYCLMQFDNGTASSGLSWLSVGMTMMCIAGYAMSAAPVVWILCSEIQPLKC
                     RDFGITCSTTTNWVSNMIIGATFLTLLDSIGAAGTFWLYTALNIAFVGITFWLIPETK
                     NVTLEHIERKLMAGEKLRNIGV"
BASE COUNT        10223 a        11240 c        10426 g         9811 t
ORIGIN      
        1 tgatctggtt aagcaggata aaatttgatg actagagtag ttattgcttt attatttctt
       61 gccggatgta cttcgcaaat gaagtattcc aatgtcgtca ggattaggaa tgtatgttcc
      121 tcagatatta atgtgtttat tcctgagtat gtttttggag gtaatgttat taagcaacat
      181 catatttact tacctgttaa tgggattgat gttttgtctt atttttatac tgaaaacatc
      241 aatgatggtt tccaatatga agaagcattc accgtaaata aagatagctc gggtaatttt
      301 gattatccgt ttgttatctt atcatcagga cgtgaaaaaa aatttgggaa aaacgatcta
      361 attgaattat ccagggacat ttcaacaaaa gacgataaga agcatggggt tgtaaagtac
      421 atgatagata gtcaggatat ttgcccatag tatgattcat atcataatca actgaaaaaa
      481 tgacattatt aatcatttgt gattttttga tactaccaag tgaaatttga tgattagatt
      541 aatattctct tttttattat gcacactgtg tgctggatgt ttatctcaac cattctattc
      601 ttgttccatt gtcatggtaa atacatgcaa agtatctatt aacatttcga cagtcaataa
      661 ttcaacacat tatgatggta aggtaagaga taattttcat cttgatatcg gagagcggaa
      721 gccaattgta tactttattt acacaggtag agagtcagat gtttttaata aaaaccctgt
      781 aaatattgtt tctgaactta gtattttgat atctgatggt aacaattcta aaactttatc
      841 tggatatcat atctcctctt tattgaaaaa atcctcatct agtatggagt ccgatttttc
      901 ttttgaaata aatgatccat ctatatgtcc ttaggattct gaaaataaaa aattctaatc
      961 tcactactcg ttggtattaa tttcaataaa aggaaagata aatcctccga tggacgactt
     1021 aacccaacgc tactacgaag ccgaaatgcg ctacctgcgt gaagcgggga aagaatttgc
     1081 gcaggcttac cccgaccgcg ccgcgatgct caatcttgat aaacccggcg cacgcgatcc
     1141 ctatgtggaa cgcctgttcg aaggctttgc ttttttaatg ggcagcctgc gcgagaagct
     1201 ggacgacgat ctgccggagc tgactgaagg gctggtcagc ctgctgtggc ctcactacct
     1261 gcgaactatc ccgtcacttt ccgtggttga actgtcgaca gatcaccggc agatgaagca
     1321 gagcgaaacg ctgagcgatt ttcaggtatt gtcgcgccct gttggcgagc gcagaacccg
     1381 ctgtttctac agcgccacgc gggatatcac gctgcatccg ctggcgttgc cggacgtgtc
     1441 attgcaatat gaaccggacg gacgttcggt tattcgtctg cgctttgaat gcggcccgct
     1501 ggtcggtgac tggtcacaga tcgatttatc ccgcctgccg ttctatctca atgccgacag
     1561 tccggtggcc tgtgcgctgc accgggcttt aacgcttggt acgcagcagt tctggttgcg
     1621 tctgccgggg caggatcgcc ggacgcttga cgcacacttt tccccgttgg gctttgagga
     1681 taatgacagg ctctggccaa aaggcgagtc ggcgttcagc ggctaccagt tgctgctgga
     1741 gtatttcacc ttccgcgaga agtttatgtt tgtggcactc aacgggcttg agctggttgc
     1801 atggccggag gggataaccg gctttgagat tgacgtggtg ctgaacgaga actggcctca
     1861 cgacctgccg tttgacagcg ataatatccg tctgcactgc gtgccggtca tcaatctgtt
     1921 cccgctcgaa gccgatccgt tacacctttc gccactggaa aacgaatttc tgctacgccc
     1981 gatgcgcatt caggacgggc ataccgagat ttattccgtc gacaacatta tttcttcgcg
     2041 ccataccggc agtcaggcgt atgtcccctt ctccagcttt cgtcaccggg gcgggatgct
     2101 gcgccacgat gcgccggaac gctattacca cacgcgggta aagcgcggcc cttccggtct
     2161 gcatgacacc tggctgattc tgggcggtga tgcgtttgat gctgaccgga tgctggagga
     2221 tgaaacgctc tctttaagcc tgaccggtac taacgggcat cttccccgta aggctttaca
     2281 gagcacgctg ctcgataggc cagttcatgc ctcacagaac gtcctgcggg tgcgcaacct
     2341 gtgcgcccca acgcagccct gctatccccc ggcgcgtgac cgcttccact ggcgggtgct
     2401 cagccacctt ggttctaact ttttatcgat gatggataac gccgaaattc tgcgcggaac
     2461 gctggcgctg tacgactgga ccgaaagcga gatgaaccgc cgtcgtctgg aggcgattgt
     2521 cgacgttcag cacagcctga tacagcgttt tgaaagaggc tttctgctgc gtggcgtgga
     2581 tattcaggtg acgctggaca gtaacggctt tgccggagaa ggtgatatca cgctgtttgg
     2641 tgaactgctg caccgctttt tcgcactgta tgccgatatc cacttattca ctcaactgac
     2701 cttaattctg caacctacag gaaagtgcct gcaatggaca gagcatcaca gccagcgcgt
     2761 accgggctga ccgaccggct ggccccggat attgcgcgga tcaattttta ccgtttttgc
     2821 cagttgctgg aacagagcca gcagaacgcg ccgctgggca gtaccgacaa ccccgccacc
     2881 gatgcggtgc gctttcgtcc ccatcccgga atgggctttc cggtcagcga gttaaagaac
     2941 gttgaacgtg acgcgggcaa tcccgacgtg ccacccacgg tgcgcaccac ctttctcggc
     3001 ctgtacggcg tggattcgcc gctgccaacc gcctatctgg actacattac ccagcgtcat
     3061 gacggacatg acgcagtgat ggcgtttctc gatattttta accatcgctt tatcacccag
     3121 tattaccgca tctggcgcaa atataactac ccggcgtcgt ttgaagcagg tgctatggat
     3181 gacatttccc gttgtctgct gggactcatc gggctgggta ttcccggcag cgagaaccat
     3241 atcgccacgc cggtatcccg ttttctggcc ctgctcagcg tgatgcgcct gccgacgcgc
     3301 acggcggaag gcgtcacggc actggtggga ctgcttgccc cgctgacgaa agcgacggtg
     3361 gtgcctcacg atccgcagcc tgttattctc ccggcccctg cgggtctgtc aaaaaattca
     3421 cgcatcagcc tgaaaacgcg aacgctgctg gggcgtaccg gcaccgacgt caacagccag
     3481 ttgctgctga aactgtatac cgaagatgcc gcagaagcac gtggctggct acctggcggg
     3541 cagctgcaca gcgatttgct ggtgctgctg cgcgtttatc tgggctggcg ctgtcaggcc
     3601 cgtctgcaac tgacgctgcc cgtcagtctg ttgcctgctg cccggctggg aaaacagcgc
     3661 gtacagatta gccgtaccgg catccttcgc gcctcctttg ccgcgcccgc gaccggaaca
     3721 gtgacggtca gtctggggcg ttatcaggga ttaatacccg ctttatccat tcgtaacagg
     3781 gagagtatga ctcatgtttc ctattcgttt taaacgtccg gcgctgctct gtatggcgat
     3841 gctgacggtt gttctgagcg gctgcgggct gattcagaaa gtggtggatg aatcgaaaag
     3901 cgtggcctca gccgttttct acaagcaaat caaaatactg catctcgatt tcttctcccg
     3961 aagtgccctg aatacggatg cggaagatac gccgctttcc acgatggtgc atgtctggca
     4021 actgaaaacc cgcgaagatt ttgacaaggc ggattatgac accctgttta tgcaggaaga
     4081 gaagacgctg gagaaggacg tactggcaaa acacaccgtc tgggtaaaac cggaaggcac
     4141 ggcatccctg aatgtgccgc tggataaaga gacgcagttt gtcgccatta ttgggcagtt
     4201 ttatcaccct gatgaaaaaa gcgacagctg gcgtctggtg atcaaaaggg acgaactgga
     4261 ggccgacaag ccgcgctcga ttgaactgat gagaagcgac ctgcgactgc tgcctctcaa
     4321 ggataaataa ccgatgtcga caccttcctt atatgaaatg ctgacgttca gtttcagcgg
     4381 cgagttacca ctggaacagg tcagcgagcg ggatcagctt atcctttccg tgatggacaa
     4441 tatgcaacgc attatcaact gtcgggcagg cacactggcg catttgccgg attacggtct
     4501 gccggatctc agtctgatcc atcagggtat ggttgcgggt attcatggcc tgatgcgtca
     4561 gattgaagaa acgctgctgc gttatgaacc acgcctgagt cagatacagg tggagttact
     4621 cccccagccc cgtccggggt atcttaatta cctgatccac gcgcagcttc ccgataccgg
     4681 ctggatacgc tttgatggcg tgttttctcc ggaaggacga attgttctgc gtcatctcaa
     4741 acagcaggag cgggcgtact gatggcaagt aacgcgaatt ttatcagcca gttcgtcatg
     4801 ggcggcgatc cctgtactta taaggaatcc ggtgaactac aggctgaaat gagtaaactg
     4861 actcacccgg cccgacctga tgtggactgg cgtcgggtgg aaaaactcag cctcgcgctg
     4921 ttccggcaaa atggcgtgga attacagacg caggtctgtt acgtactggc gataaccaga
     4981 cggcaggggc tggcagggat ggcagacgga ctcggttcac tggacatact gctccagcgc
     5041 tgggctgact tctggccggt acaggtacat tccagaatat cactgctcag ttgggtcaca
     5101 gaaaaaatgc agcaggcact gagaacgctg gatattcagt atcaggatct gccgcagatt
     5161 taccgttgtg tacagcatct ttccgccatc gaaaccacgc tgcaacagtg tgaactgtgg
     5221 catatgacga aactggatgt gctggccggg cagtttcgta atacggcgct acgtctggag
     5281 cggctggcac cacagggagc ggaaaccact atcactcccc ctgaattacc ccgccgggaa
     5341 atgaagcaac cagaaaagtc agaagaaagt ccacagccgg tttttgcaac cagacccgct
     5401 cagcaaaacg ataaggatgc cagtccatcc gcgccatccc ctgaaatctc ccggcagcgg
     5461 acatggccga tatttatggc cggaatggtt gtgatggcct gtctcggcgg aacaggatta
     5521 tggggctggt cgcagcttaa tcagccggac gcactaatcc agcgaataca actgtctgtc
     5581 atgccattac cgcagtcgct ggagagcggc gagctggcaa agctggatgt aaaggataag
     5641 gcgctgctgg ctcaggacag aacaattgcg gcaagtcaga tgcaactgga gcagttaaac
     5701 aaattgcctg cccgctggcc actggagcag ggatatcgcc agctacgcca gcttgatgcc
     5761 ctgtggccgg ataatcctca ggtcagagcg ctgaacgcgc agtggcgtaa acagcgggag
     5821 ctgagcgccc tgtccacaga ggcattgaat ggctacgcac aggcgcagag ccagctacag
     5881 cgcctgtcgg cgcagctgga tgcactggat gagcgtaagg ggagatatct gaccggttcg
     5941 gaactaaaaa cggcggtgta cggcatccgg cagtcgttaa aggagccgcc gctggaagaa
     6001 ctgcttcggc aactggaaga gcaaaaacag accggagagg tttcgccgac gctgttgacg
     6061 caaattgata cccggttaaa tcagttgctg aatcgctatg taattttact ggatacgaag
     6121 gtggaacaaa gtcagtaaac gtcgggggat ttatgcacca ataagggata tgtgaccttg
     6181 ccatttttta aaaggagtct ttgtgtacaa aaaagagagg aacaggccat tcgaaacgcg
     6241 tgaagaggtt ctggcatatc ataagcggga aaaaataccc tgtctggagt gtggcaagtt
     6301 gctcattttt ttaccgcgcc atatctggtt tgtgcatgga atacgcgctg acgaatatcg
     6361 tgtaaaatgg aacataccga agcacatcgc actggcaggg atttcatatc tggagaaaca
     6421 aagtgaatat atgaaggcga gaatagcaaa gggaaagctg gatcccgcag aacaaatagc
     6481 catgatgaga ataaagggaa ggcaactaaa gtcagatcct gactggcgta atcgctccgg
     6541 ttctatattg aagaaacaat atgcccgacg agatatcctt aaaaacaggg tatgggaaag
     6601 atctcccagc ataaaaagtg tctctgtgga gttgaaaaca gaagctataa ggcgaatgaa
     6661 aaacaggaag gtcgtcgggg aaaaagtcca ggatattgcc gatgacctga acgtatctat
     6721 cagcagattg tatcactggc taaagatgta ggcgctcatg tgctctcaat gccttcaata
     6781 aagccgctat gcgcgaaccg gcacatctgg tagactgttc tcagtgagtc aagcaaactg
     6841 cctacttttc taacttttaa tcatgaataa ccagcgcctt gagtatagct ggttcgaata
     6901 tactcgttga ttcacatcag ataatgagtg tataattcgg tagatagctt gggttcggga
     6961 acagtgaatg ccttaagttt caaaaggtta gattaacctc ttgactgtgg cccccgcaac
     7021 caattattga acaccctaac gggtgttttt ttgtttctgg tctcccataa aaaaagcgcc
     7081 attcagcgcc tttttatcat ccccttctcg ccagcgtcgc cccatcggca aaatacgctt
     7141 taattcccgc aagaatagac tccgcaactt cctgctggaa agtcgccgtt ttcagtttac
     7201 gctcttcctc aacgttactg ataaacgccg tttcgaccag aatggaggga atatctggtg
     7261 cctttagtac ggcaaacccg gcctgttcaa cttgattttt atgcagcttg ttgattttac
     7321 cgagcttatt cagtaccgct ttaccaaact tcaggctgtc ggcaatggtc agcgactgca
     7381 ccatatcgaa catggtgtgg tcgacatagc ggtcaccgct tttgctcacg ccaccaatca
     7441 agtccgaggc gttctgggtt tgtgccagat attttgccgc agtactggtt gcacctttgg
     7501 ttgagagcgc aaacacagag gaaccgctcg gctgacgact ggtaaaggcg tcggcatgga
     7561 tagagacaaa caggtcagca cgctgtttct gggcttttgc tacgcgcact tgcaacggaa
     7621 tgaagatgtc ttcattgcgc gtcatgtaca ccttcatatt gccctctttc tcgatcagag
     7681 agcgcaaacg gcgagctatt tgcaatacca cgtctttttc gcgcgttttg tatttcccca
     7741 ccgcaccgga gtcttcgcca ccgtggccag ggtcaagcat aatgacaatc ggacgatcgc
     7801 gccctgcttt acctggttgt ggaccacttt gcgctggcgg cacctgcttt tcgaggtcgc
     7861 ctttgttgta atcctccagc agcgccagca gcgggtcctg catatcctgt gcattggccg
     7921 gatagaggtc catcaccaga cgctctttaa acccggcgac cggcgcaagg gcaaacagct
     7981 gcggttttac gttttgcttt aattcaaaaa ccatccgtac ggtttgcggg tcaaattgcc
     8041 cgacgcgcgc cgacttgatg aacgggtcgt ctgcacgaat ttgtgccgcc atccccttga
     8101 gtaccgagtt caggtttaca tcttcgatat ccaccaccac gcgttccggg ttactcaacg
     8161 cgaactgctt atatttcagc tgacgatttg attctaccgt cacacgggtg tagctggacg
     8221 caggccagac gcgcaccgcc acgacctggc tgaccgcagc cagactgacc tgacttacgc
     8281 tcaatagcca catggcaccc gcgccttgca gtaaacgacg acggctgatt gcagtgttgg
     8341 atcctgacat gcctctcccg agcaaaagaa atctaagctg tgtaacaagt aaacgactaa
     8401 tttgaccgga aactttagcg aaagacgcat aatctgtcat ctaataaacg gtaaacattc
     8461 tttttatatt cacggcatta ctgataaaaa agtcgctctc gcataaaatt tacacttgca
     8521 ccctgcgaaa aaacagaata aaaatacact aatttcgaat aatcatgcaa agaggtgtgc
     8581 cgtggtaaag gaacgtaaaa ccgagttggt cgagggattc cgccattcgg ttccctatat
     8641 caatacccac cggggaaaaa cgtttgtcat catgctcggc ggtgaagcca ttgagcatga
     8701 gaatttctcc agtatcgtta atgatatcgg gttgttgcac agcctcggca tccgtctggt
     8761 ggtggtctat ggcgcacgtc cgcagatcga cgcaaatctg gccgcgcatc accacgaacc
     8821 gctgtatcac aagaatatac gtgtgaccga cgccaaaaca ctggaactgg tgaagcaggc
     8881 tgcgggaaca ttgcaactgg acatcactgc tcgcctgtcg atgagtctca ataacacgcc
     8941 gctacagggc gcgcatatca acgtcgtcag tggcaatttt attattgccc agccgctggg
     9001 cgtcgatgac ggcgtggatt actgccatag cgggcgtatc cggcggattg atgaagacgc
     9061 gatccatcgt caactggaca gcggtgcaat agtgctaatg gggccggtcg ctgtttcagt
     9121 cactggcgag agctttaatc tgacctcgga agagattgcc actcaactag ccatcaaact
     9181 gaaagctgaa aagatgattg gtttttgctc ttcccagggc gttactaatg acgacggtga
     9241 tattgtctcc gaacttttcc ctaacgaagc gcaagcacgg gtagaagccc aggaagagaa
     9301 aggcgattac aactccggta cggtgcgctt tttgcgtggc gcagtgaaag cctgccgcag
     9361 cggcgtgcgt cgctgtcatt taatcagtta tcaggaagat ggcgcgctgt tgcaagagtt
     9421 gttctcacgc gacggtatcg gtacgcagat tgtgatggaa agcgctgagc agattcgtcg
     9481 cgcaacaatc aacgatattg gcggtattct ggagttgatt cgcccgctgg agcagcaagg
     9541 tattctggtg cgccgttctc gcgagcagct ggagatggaa atcgacaaat tcaccattat
     9601 tcagcgcgat aacacgacta ttgcctgcgc cgcgctctat ccgttcccgg aagagaagat
     9661 tggggaaatg gcctgtgtgg cagttcaccc ggattaccgc agctcatcac ggggcgaggt
     9721 tctgctggaa cgcattgccg ctcaggcgaa gcagagcggc ttaagcaaat tgtttgtgct
     9781 gaccacgcgc agtattcact ggttccagga acgtggattt accccagtgg atattgattt
     9841 actgcccgag agcaaaaagc agttgtacaa ctaccagcgt aaatccaaag tgttgatggc
     9901 ggatttaggg taagcgatga aaattgtcgg atgcgacatg cgtaacactc gtgcgtcgca
     9961 tccggcaatt acgtttattc ccgcgaacta aacaacgccg ccagaccact gcgccgctca
    10021 gtacgagtgg cgattgccgc acttaatata cgctcatcgg catacagcga cagacggcga
    10081 cgcgcgcggg tcaccgcggt gtataccagc tctcgcgtta ctaccggcgt gcgttggctc
    10141 ggtaaaatca acgccgcatg gtcgaactcc gatccctgcg atttatgtac cgtcatcgcc
    10201 cacgtagttt cgtgctctgg caagcgactc ggttgcacag acttaatatt gccgtccggc
    10261 atcgcaaacc agacgcgcgt cccctgcccg cgatccagcg caataccgat atcgccatta
    10321 aacaacccaa gcgcgctgtc attacgggca atcatcaccg gtcgaccttc gtaccaacga
    10381 gagtgcggat gacgatgaat tttgcgcttc tgttgcataa actgctcaat tcgctcattc
    10441 agtccagcca cgccaaacgg cccttcccgc agggcgcaca aaagttggta ctcattgaac
    10501 gcctgaatga ttaaatccgg ctcagcacgc gcttgcagca gatccagata acgtccataa
    10561 cccgcaagag cttcctcaag catcgcaata taatcttcgc cgctctgtaa aagtcgtttt
    10621 tcgatatcag taaaatcctg ctgaaaaacg gttttcactg ccgttttatc accacggttg
    10681 atcgccgcag ctaactgacc aatgccagaa tcgctgccga aacgatagct tttttgcagc
    10741 aggcagagac tgtcgcgcaa agatgccgct tctgtgccgg ttcctgccgg aacgtgagtc
    10801 cccgtcaggc ggcttagctg cccggcacgc tcggcggtaa agccggcatt ggcataagcg
    10861 cagatatcgc ccagcacagc cccagcctca accgaggcca gttgatcacg atcgccgaga
    10921 aagatcactc gcgcatgatc gggcaaggcg tcgatcagtc tcgacatcat aggcagatcg
    10981 atcattgacg cttcatctac caccagcaca tcaagatgca gcgggttacc ggcatgatga
    11041 cgtaaacgct ggctccccgg ctgcgcaccc agcaatcggt gcaaagtgct ggcatcttcc
    11101 ggaatgcgtt tcttttgttc atcggtcagc ggtaactgcc gcaaagcctt gccgagagat
    11161 tcggttaagc gcgcggcagc tttacccgtt ggtgcagcca gacggatacg gcagcgttcg
    11221 ccgtctgcca tttgaattaa cgctgccagc aacttcgcta cggtggtcgt tttaccggtg
    11281 ccagggccgc cggaaatcac cgagatccgc cgcgtcagcg ccactgccgc tgcaactttt
    11341 tgccagttaa tttcatcgct tactggaaaa agtttgtcca gggtttgcgc cagtagagct
    11401 tcatcaacct caatggcatg attcacctca ttgaagaagc gcgctaccgt ccgctcgtta
    11461 caccacatgc gattcaaata aagacgatcg ccacagagga tcatcggcgt gggttcatct
    11521 cccctgctga ccgcttgaga agccagcaag cattcttccc aattttgtag ctcaccgatt
    11581 tcactgacac aggtcgccaa cagcggatgc gacgcctcgt tattttccag tcgtgaaagc
    11641 ggcaaacaga cgtgtccctc tccggcatca tgacttaaca gtgccgccgc gagggtgacg
    11701 gcaggatgtt catctcccgc cacggtcagg gcaaattgca catccagcgg gcgtagctgt
    11761 ttgtgctcca cagcttccag taattgcttt tgcaatttca ttacgcctcc tccagggtca
    11821 taccggcaaa catctcatcc atcagggcaa tcaacccggc gttgggtcgg gttgtgtaaa
    11881 tcccttgttg cggatgttct ttatcaacgc cacgcaggaa cagatagata acgccgccaa
    11941 agtgacgatc atagtcgtaa tcagcaatgc gatggcgcag ataacgatgc agcgccaggg
    12001 tataaagctg atattgcaga tcatagcggt gtgcctgcat cgccgctgcc atagcctgtt
    12061 gggtgtaagc cgaactgtct tcacccagcc agttggattt atagtcgagc aggtaataac
    12121 gcccttcgtg gcggaatacc aggtcgataa agccttttaa catgccgcgt acctgcatga
    12181 actccagcgg cgggcagcca gcggatagcg gatcaaactg gcgaattagt gcatcaagct
    12241 ggctggcgat gagcggttca ctaatcggca ggtaaaactc catctccacc tgtttatcgc
    12301 ggtcggaaag ctgattcagg ctaacacccg tttcattgag aggtgcctgg aggacagccg
    12361 tgatccactc ggtcaacact ggttcccact gcgattcaaa gccgccgagt tccagttttt
    12421 cctgtaccca gttcgggtca accggctggg taaaatcgag gtcttcaaac aaactgtgca
    12481 agaatgtccc tggtgacgca ccgcgcggga actgatgcgg tgttaacgtc ggttcttcaa
    12541 cgacgctgac cacgcctgcg gcatcaacat ccagccgtgg catcagatcc tgagcgatac
    12601 cgtgaccacg ctgctgcaaa ccggagtagc tggtgacacg ccagttatcg ccgggcaatc
    12661 gttgtagcgt cctcgcattc agttctgcag ttaaagcatc attaacctgc cagggctgtt
    12721 tatcacccgt ttgtgccgtt tgccaggcaa tatcatcatc gcataacgct tcaatacagg
    12781 tgcgaagccc tgccgcatct tgcggttccc ctttttgcag caaacgcccg agcgcacttt
    12841 ggtggacgtc ggtgtcacct tttttatcgc cacgacggcg caccagcggt gcaacgccga
    12901 gactgcaatg ccaaaccgaa cgtgtcagcg ccacgtaaag caaacgcaga tcttccgcca
    12961 gacgttcggc ctccgcgagg tcgacgcttt ctggcgcagc attaagatcc agaactgcct
    13021 caaacgagtg gcgatcgtga taaaacgcct gatcctggac gcggaaattg gtgataaacg
    13081 gcagccagac caatggatat tccagccctt tcgatttgtg gatcgtgaca atctgcacca
    13141 gatgtttatc actttcgaga cgcatttgtt ggctggaggc attactgtct ggctcgagga
    13201 tatgttgcga taaccagcgt accagcgcat gttcactttc cagctgcgtt ccggcttctt
    13261 gtagcagttc gctgatatgc aagatatcgg taagtcgccg ctcaccgcct gccgttgcca
    13321 gcaagttttc tgcaatgtta cgcgccgaca tcagcgcccg cagcatcggc ataacgccac
    13381 gtttgcgcca gatttgccga taaccatcga actcttcaac taccgcatcc cacgcatgtt
    13441 cgtcattatt cagcgtttcg atatccagcg cgttcagccc catcattgac gttgccagcg
    13501 cactacgcag ggtgttctca cgttcgggcg tcatcaccgc ctgcaacaac caaagcattt
    13561 cctgcgcttc cagagtttca aaaacactgt cgcggttcga aaggtaaacg gaagggattt
    13621 ccagcaacgt taaggcatcg cgcacctggg cggcctcctg gcggctacgc accagcacac
    13681 tgatgtccga agcacgcacc ggacgcgcgt cgtcgccgtt catcagcaac gcttcgcccc
    13741 gctgtccggc ttgtagccag tcgcggattt gcgcagcaca tacctgcgcc atggtacttt
    13801 gatagtcgcc aacgccgcag ctttcgcctt ccatcagcca cattttcatc gcaggctgcg
    13861 tttcaccttt aaatacaaaa cgtaacgcct gatttttccc ggctgatttc actggaataa
    13921 acggtatttc gcgaaacatg aacgcgtcat cagtctggct gaaaagctta ttcacgctgt
    13981 tcaccattcc tggtgcggaa cgccagttgg tgtctaaagt gtagtgggcg tgaacttcgc
    14041 tacgcgcctt catataagtg aagatatccg caccccggaa tgcatatatg gcctgcttcg
    14101 ggtcgccaat cagcaacaat gcggtttccg gctgatggtg ccagatacgg cgaaaaattc
    14161 ggtactgctg ggggtcggta tcctgaaatt catcgatcat tgccaccggg aatcgcgtac
    14221 ggatcgccgc tgccaacacc tcaccgcttt cgctacgcag cgcggaatcg agccgactta
    14281 acatgtcatc aaaacccaat tcgccacggc ggcgtttttc acgcgctact gtttcgcgga
    14341 tctcagccaa tgcgcgggtg atcaccagat cgcggatcga caatggttct gcaagcagtt
    14401 gatcgatcgc ctcaaacagt ggatgtcgcg gggtttcccc cccggccttc gtgcgatctt
    14461 ctaagaaacg ctgggagaat ttttccagcg actccggcaa ctgataactg tttgtctctt
    14521 cttctgccca ggcgctgatc ttttcgatcc atttagcctg attgctacgg ttaaacttgc
    14581 gtcgatcaat accagaagat tcgatcagcg catcaagttc acccactgcg tcgcgccact
    14641 gctgttttac cgtatcaata cgcgccacaa tttgcgcgtg gcgggaagcc agcgtttcat
    14701 catcgggcgg cggtgctttg ataaccggtg cttcgccttg cagataacga ttaatatcgc
    14761 gcagcaacgc ctgcggccct ttccaggttt caaagaccac cagggcaatt tcacgcggca
    14821 gcgggtagca gtggcgacgc cagaaatcgg cgcaggcctg gtagcgtagc agagactcat
    14881 cttcaatcag ctgctgctca aacagcatac cggattcaaa ggcattcagg ttgagcatgc
    14941 gctggcaaaa accgtgaata gtaaagactg ccgcttcatc catctgccgt tcggctaaca
    15001 acaaccactg cgcggcttgc gctttatcgt cgatctcttc cagcaggcgt tcgtacagtg
    15061 gattgtcggt ggtttcacgc agacaggcga tgcgcaactc gtggatattg ctacggatac
    15121 gaccacgcaa ttctgccgtg gcagcctcgg taaaggtgac caccagcagt tcttcaacgg
    15181 tcagcgggcg gggaaaggcg gcggaaccgc ctagtccaag taacaggcgc aaatagagcg
    15241 ccgcaatcgt aaaggttttg cctgtgccgg cagaggcttc aatcaggcgc tcgccctgta
    15301 agggcaagcg caaaggatct agtgtctcgg cgacatcact cattcttttc actcatcagg
    15361 ggcattgttt gctgcaacgc gctgacgttc tcccacactt tccagccttc aggatgcaca
    15421 tattcggctt tcccgttctg gctgccggaa atctgcgaca gaatagccat gccttgcggc
    15481 tcgaccaccg cctgatggaa gaaatcagca agtttttgcg gcgtcagcag ttttatctgg
    15541 gccacgattt tatcacgcga atcgaagcgc atattgccgc gatcgaaatc tttacttaac
    15601 ttcgatgctt cttcgccgag cgtttgcggt gcctgcagca tctgggtaat taccgcctgc
    15661 tggatttgcg caaactcttc tggcttcatc gcccgcaatt ttgcctctgc ggttgggaaa
    15721 aacgccttgt aacgctccca caagaaggaa ggctgtttat cattgctttg caaaaggaag
    15781 cccatgcccc actgacgccc cacgctcatt ggaaatgcaa acacggcata gcccaattgt
    15841 tcttcggtac gcaactgatt gtagaaccac ggctgtacga tctgccccaa cagagagcta
    15901 taggctgagc tggtgtattc atcgtagcca gtcggtacaa ataccgctgc cagtgcggag
    15961 tcggtgctgt taccagcttt ttcaaagatg acggattgtt ttttatcgac cacgacatct
    16021 ttgttacgac accactctga accatcagcg cccaactgtt tttgcacatc gcgtgccagc
    16081 gttgttgcct ggtcctcggt catgttgccg ataaccataa actctggtcg agcccctgat
    16141 tttaaggcgt cgcgataggc cagcacctct ttcaacgtaa tggagggcaa aattttgcgc
    16201 cgttcatctc gcgagaagta cggcacttgc gagagcatct gcgcgggcat aatcgcctgc
    16261 tcgaacgctt tgcccttttc tgcggaatcc atcatctggt tataccagga cttcgcctgc
    16321 tcaagctgat cttccgtggc ggtatagcta aagtagcctt ccagcaatgc ctggaacagc
    16381 tgcggcagac gctgggtgta accattagca ttaaccataa ggccgttgtt agcgttggtg
    16441 gaaaaactta tgccaccaac cgacgcctgg ttgcttaact gatcaagcgc cagccctgcg
    16501 agataatcat tgagcgcaaa catcacctga ttgcgggcgc tgtccatggc tttcggatta
    16561 cgcaaaatca ggctgacatc ggctttgggc tcgctggcaa aataacggct tggcgcatac
    16621 actactcgca gattcgactc atcaacaatc agctctggat ggtcgtattt cttctctgac
    16681 ttaatcagcg agaaagcgtc aggaatataa gggttaagct ctggcaaaga gagcgcaatg
    16741 tcggcggctt ttttctgcca gtcggcgaaa gtttgtgcgc tgattttatc gacctgatac
    16801 ggcgcatcga caaagtaagc cgttttgttg tgcggctctt tcgggctgat ataccagata
    16861 cgcgcattct gcggcgtcat catcgccaga cgttccttta ctgctttagc atcgtaccga
    16921 tcggcaatat tgactgcatc cagcgtatgc tcaacaggaa cgcgaatcat ggtatctgcc
    16981 agccattcga cgtaatccat atcacgggtg attgacggat aacggaagtc gatatccagc
    17041 acattcgcca gttcatcgaa gtattgttta tcgatccctt tttcacgtaa caaattgagg
    17101 tagctaaaaa tagccgccac aacctgatcg cgattcgcca gacctttatc ggttaaagac
    17161 gcagagatcg ctaatacgcc gctgttgccg ttgacgatag gatcggagtt ggcgctaatg
    17221 ccctcaacta atccctgctt ttgcagccag tcggaaagtg tacctgggct gcgattacca
    17281 atcagatagg taatcaattc atcggttttg ctacggaatt tcgccgagtt gttatcaata
    17341 cgaaactcta cgcgcaacac tttacgcggc agcgccggga cgtaatgaat gataatgccc
    17401 ttttgcgcgt cggtgactac cggcacggtg atttccggtt ttttgctctc tttgttcggc
    17461 acgcgaccaa aggtgtccgc cgccattttt gccaactccg gcagcggttt attgctgtaa
    17521 ataaccgcct tcatcagatt ggcggaatag tacttctcgt ggaaatcttt cagcgcctgc
    17581 tgcaccggat taccaggttt gtcgcttaaa gtttcgaggt taccaccaga aaactttgaa
    17641 ccggggtgtg ccgggttaat ggtttctgcg ctgacctgtg ccatgcgcat cccgtcacgc
    17701 gtacgcgcca tggttaattc agcgttcact gcattacgct cacgttcggc gtatttcttg
    17761 tcgagcaagg gttctgcaat agcatcagcc aggcggtcta ccgcaccagg caaggcgtcg
    17821 ttctcaactt ccagatagaa agccgtgcga tacggcgcag tgctggcatt gtgactaccg
    17881 ccgtgcattt tgagatattc ggccagactg tcagcctgcg ggtacttttt cgaccccatc
    17941 agactcatat gttcaaggta atgtgccagc ccctggtacg cctcgggatc ttccagcgac
    18001 ccaacgggca ctaccagcgc cgagagcgat ttaactgcct gcggatcaga aaccagcaag
    18061 accaccatac cgttatccag acgtatagcc tgatactggc ggttatcttt atcactttta
    18121 cggatggttt cctgaatcgg ctgccatccc gtttctgcct gacttaatgg tgcccaaagg
    18181 gcaactaaca acaataatgc tttgaaccag gtgctgcggg gcattcacgg acctcataat
    18241 caacttaatt ttctgtcaga ttcaacacgt taacgcaaat catctgccag aatttaatct
    18301 tgtgctgcac gagtcagcct atgtttatat aaccatcagt ccgtgactgg tgcgcatcat
    18361 aaagtaagcg gatagattgc gcaattttta tacagcactc atgactgatt aaagcgaaac
    18421 agcggtaaca ggaaacgttg cgactgttca acgatggcct ccattgtctc tggtgttaat
    18481 tgccgccaga gccgttgata ccagatatca tcaccttcgc cacgcaccat catgttgcct
    18541 tcgtaagcct gcaggaattt cgtacgggct ttttgcaacg tggaatcgtc atccagcatg
    18601 gcatcgtttt gcgcgtcata acaggttttt agccacgcgc cgccactttc aggtaacacc
    18661 agcaatggcg cggacatccc ttcacgatac ccctcaatca gttgtgagag gtaatgcaaa
    18721 gcctgttcgg ctgcaagcgg cggaaaacgc cactcgccgt ctttgcgtag aaaaaggcga
    18781 ctttcaccat taccaccgct ggcacagtag acaaggtgtt ccagccaaag ttgcattccc
    18841 tgcgccacac ttaataaaga gggacgccag cgcaacaagc catccggctg cacctgcggc
    18901 aaccagccag ttatctgcac accgttgcag gcgagatcaa tttccatact ctgccccggc
    18961 tggcgacagg caatgactct gtcggcaagc tgctgcatct cctggcactg tgtttcccag
    19021 aaaatttcac caaaagcgcc atacggtaaa tcccctgccg cccggaagcg gcggaacaag
    19081 cgttcggcat catcctgctc aaccagtgca ttcaataact gctgattgat ttgataacga
    19141 ctaagccctt caagaataaa tggctcggtg tcggggattt cgctgtcttc agtacggaag
    19201 ttcacctgca aacgcatctg gaagaacgcc cgcaccggat gtgcccagaa tcgttgtagc
    19261 gtttccagcg gcacggtttc cggtaaggta aacggcagcg gctgaacaaa ttcagaatgt
    19321 gctttaccag cctggctggc cgcaggtagc cattcacgag catagctttg tcgttcgcct
    19381 ggctggtagt tttgtggatc aaacggcatc cgggtatgga ggcaagtaag atgcgctttt
    19441 acccttgcct cgctttcatc acagttgagc gcttcatcgc ccggtagata atgactttgc
    19501 ccgatgtagt cgatcagttc ctgcaccagt accgacggga aacgttcact gttatcctga
    19561 atggagcgcc cgatatagct gatataaagt ttttgttgcg cggaaattaa cgcttccagg
    19621 aacagatagc ggtcatcatc gcgacggcta cggtcgccac gcttcggttt ctggctcatc
    19681 aggtcaaagc ccaatggcgc aagctgacgt ggataaacgc cgtcgttcat tcccagcagg
    19741 caaaccactt tgaacggaat tgaacgcatt ggcatcagag tacaaatgtt aaccggcccg
    19801 gcgagaaaac gctggctgat acgttcttga tccaggcgct gtgccagttc atcacgcaat
    19861 agtgacagcg gcaccgcgtc gccatactgc gcacctaaac cttcggcgat aatcgcctgc
    19921 cattgttgtt cgatcagcgt catcgccgct tcggtttccg catccggcag gaagaaggcg
    19981 ttgagcatat cgcgacaaac cggcaaccac tcttccagcg gacgctcctg tgccagcccg
    20041 cgacgccaga tgtttagctg cattagcagg gaagccagat gccccaccag ttctgcaatt
    20101 aagccgctcg attcatcata aggtagaacc gattgccact cgccctgcgc gctctccatc
    20161 gcgtaaccca gcaacatgcg cgtcaggcca aaccgccagg tgtgttgtcc ggtggcgggg
    20221 agttccagct cgcgaacgtt gtcgtcatct atcccccaac gaatgccgga ttcgttgacc
    20281 cactggcgta aataacgcag cccttcttcg gtgatgtcaa accgcgccgc cagcaccggc
    20341 acatccagca gcgccagcac atcctctgac acaaagcgac tgtcaggcag tgataacagg
    20401 ctgataaacg cttccagtac cggatgtgac tgccgcgcac gacggtcgga aatggcgtaa
    20461 ggcaggtaac gatccgcagg tgcgctacca aacactgcct gaataaacgg actgtagctg
    20521 tcgatatcag ccaccatcac gatgatgtcg cgcggagtaa gtgtcgggtc ttcctccagc
    20581 atcgccagca ggcgatcgtg taaaacttca acttcacgct gcgggctatg gcaaacgtgg
    20641 aaggtgatac tgctatccag tggatcaagc gggcgtttgt tatcgctacg ggaaaactct
    20701 tcgatgttca caccagcaac ggcgcggttt tccagttcca gaatgtcaga ctgaatgtta
    20761 tgcagcaggt tatctggcat cacatcgaca aaggcgtcca gctcctggct gctctccagg
    20821 tcagaaagga gataaatgta gtcgcgccca agcttacccc atgaagccag tagcgggttg
    20881 ccgacatcct gttcaccgtc gctgttaaag agctgtccgg cattttcgct atcgcgaaat
    20941 agcggcaatt cgcgatcttc aaaactgtgt cgacgctgac gagtcagcag tttcgccaga
    21001 taagcaggat ctttaatatc gccccagtaa taacggcagg ggttggtaaa caggagatgg
    21061 atttcaatat gtttacccag cgcctggagc gcctggagat aaacaggcgg taacgcggaa
    21121 ataccgcata taaagacgcg cgaaggtaac cccggcgggc aggtcgtcgc ggactccagc
    21181 gtttcgataa agcgctgata gagattggcg cggtgccagc gcggttgccc gagttgatgg
    21241 gtatattcca ccaacgcctt ccacaacggc gcttgccagg cctgtgcttc tcccagccct
    21301 tcaaccaaat gtcctgtttc ccactgtgcc agccactccg gacgatagac cagatactgg
    21361 tcaaacaggt ccgccgcttt tgaagaaagc tggaacagtt ttcgcttgtc gctatcgtca
    21421 gtcagataat gccgcaacag ggtaaagtct tcgcgatcca gcaattgcgg cagcagagtc
    21481 atcagtttcc agctcatgct ctgtttgtta aaggcgctct ctttggggat ttccggtaac
    21541 acccggacga acatatccca gataaagctc gcaggcagcg gaaaatcaat gtttgccgca
    21601 ataccaaact tttgcgacag ggtcatttgc agccactgcg ccataccggt actttgcacc
    21661 agaatcatct ctggttcgaa aggatcgtcc agccgttcgc gttcgacaat aaactccatc
    21721 aacgcttcca gcacgtccag acgattggaa tggtagaccc ttaacatagc ggctcctgac
    21781 tactgacgat tcgggcaatg caggcgggtc atctcgcctt ctctgccccc gggtgaaact
    21841 agcgtaacgc tgatgctgac acatcccgcc tgcgatgtct gcattcggtt gacctgccag
    21901 ttggcaggtg gcgaaatcgc gcgcagttgc gtttgctgcc agccatgctg ccagagctgt
    21961 tggtactggt ttctgctggc aagactgttc attaatgttc gctggaaacc cgataacgca
    22021 gtgacaatca tcaccatcaa caccatcgcc aacattacct ccggcaggct aaagccttgt
    22081 tgattcttca gggaagctga cataacgccc tctctttcag cggacaaaaa tcgctccagc
    22141 cgcgtggcga aaaaacaatg tttccatcaa tgacttcgcc tgttcgccac aacgaaacgc
    22201 cttcataacc ggcaatcaat aaggcttcat tatctgccag taaacgcaaa caaacctggg
    22261 catcggttcc agcgtactgc gagcactgaa ctgctggctg cgtctgccag gagtgcattt
    22321 ttccccacgc cagcgccgac tgaacgatgg cctggcggcg caatgactga ctttccatgc
    22381 tcacgcgaga ggcaaaactg cgatcctgct gactcattcc ttgcaatagc aagctaccca
    22441 aaaccagcag catcaggacc agagccagtg acgaaacacc tttttcgcgg ttcacaggtt
    22501 gaatcctgtc acgctatagc tggcatccac cacggtttgc ggttcagact tactggcagc
    22561 acgcatatta accgtcaaca ccggcgagaa gccgctgaca tcctgacgta cgacctgaaa
    22621 agtgtcgata atgatggcat ccggattagt gactttatcc catcccttac cttcacagga
    22681 tgccgcaccg cgtagcgttt ccagcacatg ctccttcaga cgaaatccaa tctggtcgga
    22741 ctcttttacc ggttcgcgat cccagatacc gttactgttc gcatcccact gcacaatgat
    22801 acagtcaccc tgtccgacaa tttccagccc ttcgccggta cagctgccat gacaataacc
    22861 cgccctctgg agatgcttcg caacggtaaa tacccgcagc cagatttcat cttccagcgc
    22921 cagcttacgg gtgctcgtta aactttcacg ctgtaacgca ggcagaaagc gtgctgcccc
    22981 cagcaacaat acgctactga tcgccatagc aatcaacact tccagcagag aaaaaccttg
    23041 ctcttttaca ggcatccttc tgtttctcct tgctgacaaa gccggagtct tccccacggc
    23101 gaaaccacca gccaccactc gcccgttgag tttttgaagc gaatatgccc ggcccatgcg
    23161 gtattgcgca ggccaaagaa agcaagcgaa ggtgtcaggt cgctcatttc gacttcgggc
    23221 cagcgtggca caaagaccaa tggtgaactg ccatgacagg tattcgcccc agcaacggaa
    23281 ctcacaaggc accataacgt cccctccctg ataacgctga tactgtggtc gcggttatgc
    23341 cagttggcat cttcacgtaa atagagcaaa tagtcccgcg cctggctggc ggtttgccaa
    23401 agccgttgcg actgctgcca gtattgccag ccatagagtc cacttgcgct tagcatgacc
    23461 aaaatcagca tcgcgaccag cgtttcaatc agcgtataac cacgttgtgt tttcatgccg
    23521 gcagtatgga gcgaggagaa aaaaagacga gggccagttt ctatttcttc ggcgcatctt
    23581 ccggactatt tacgccgttg caggacgttg caaaatttcg ggaaggtgtc tcgaagaatt
    23641 taatggaggg taaaaaaaac cgacgcacac tagcgtcggc tctggcagga tgtttcgtaa
    23701 ttagatagcc accggcgctt taatgcccgg atgcggatcg tagccttcaa tctcaaaatc
    23761 ttcgaaacgg tagtcgaaga tggattcggg tttacgtttg ataatcaact tcggcagcgg
    23821 acgcggttcg cggcttaatt gcagatgagt ttgatccata tgattgctgt acaggtgcgt
    23881 gtcgcctccc gtccagacaa aatcgcccac ttccagatca cactgctgcg ccatcatatg
    23941 caccagtaac gcgtagctgg caatgttaaa cggcaggccg aggaaaacgt cacaggagcg
    24001 ctgataaagc tggcaagaga gtttgccgtc tgccacatag aactggaaga acgcatggca
    24061 cggtgccagc gccattttat ccagttcgcc tacgttccac gctgaaacaa taatgcggcg
    24121 cgaatccggg tcgtttttca gctggttcag taccgtagtg atctggtcaa tatgacgacc
    24181 atccggcgtt ggccaggcgc gccactgttt accatacact ggcccgaggt cgccgttttc
    24241 atcggcccat tcgtcccaga tggtgacatt gttttcgtgt agataagcaa tgttagtgtc
    24301 gccctgcaga aaccacagca gttcatggat gatggaacgc aggtggcaac gtttagttgt
    24361 caccagcggg aatccatcct gcaggttaaa acgcatctga tgaccaaaaa tggaaagcgt
    24421 tccggttccg gtacggtcgt ttttctgtgt gccttcgtcg agcacttttt gcatcagttc
    24481 taaatactgt ttcatggttc ctcaggaaac gtgttgctgt gggctgcgac gatatgccca
    24541 gaccatcatg atcacacccg cgacaatcat cgggatggaa agaatttgtc ccatgctgat
    24601 gtactgcacc caggcaccag taaactgcgc gtcgggctgg cggaaaaact caacaatgat
    24661 gcgaaacgcg ccgtaaccaa tcaggaacaa acctgagaca gctcccattg ggcgcggttt
    24721 acgaatatac aggttgagga taataaacag cactacacct tccagcaaca gctcgtaaag
    24781 ctgtgatggg tggcgcggca gcacaccgta agtatcgaaa atggattgcc actgcgggtt
    24841 ggtttgcagc agcaaaatat cttctgtacg ggagccaggg aacagcatgg caaacgggaa
    24901 gttcgggtca acgcggcccc acaattcacc gttaataaag ttgcccagac gcccggcacc
    24961 aagaccaaac ggaatgagtg gtgcgataaa atcagagacc tggaagaagg aacgtttagt
    25021 acggcgggcg aagataatca tcaccacgat aacgccaatc aggccgccgt ggaaagacat
    25081 gccgccgtcc cagacacgga acagatacag cggatcggcc ataaactgcg ggaaattgta
    25141 gaacagaaca taaccaatac gtccaccgag gaagacgccg aggaagcccg catagagtaa
    25201 gttttcaact tcatttttgg tccagccact gcccggacga ttcgcccgtc gtgttgccag
    25261 ccacattgca aaaatgaaac ccaccagata catcaggccg taccagtgaa gcgccacggg
    25321 tcctattgag aaaatgaccg gatcaaactc cggaaaatgc agatagctac tggtcatctg
    25381 tcaccacaag ttcttgttat ttcgctgaaa gagaacagcg attgaaatgc gcgccgcagg
    25441 tttcaggcgc tccaaaggtg cgaataatag cacaagggga cctggctggt tgccggatac
    25501 cgttaaaaga tatgtatatg atccgcgcta taaccctccg cgaatcagcc cgcccatgcc
    25561 gcgacgctcc ataaaggctg caacctgatg gcgaacttcg gtcgccagtt gcgcttccag
    25621 actacgctgc gcaagatttt ctgcgtcggc ataatcaatg cgccgcagca ggtattttac
    25681 ccgcgctaca gaacgtccgt tcatagacag atggcgatac ccaagcccaa tgaggattgc
    25741 cacgcacatg ggatcgcccg ccatttcacc gcacaaacgg agatcgattc catgtatttc
    25801 cgcttcccgg gcgatcatcg ccagagctcg taacattgca ggatgaagac tgtcataaat
    25861 gttcgccacc cgggtattgt tgcgatcaac ggccagaatg tattgagtca gatcgttggt
    25921 gccaacagag atgaaatcga cccgctttgc cagatgcggc agcataaata ccattgacgg
    25981 cacttccagc atgatgccga tacgtggttt gggaatttcg taaccgatca tctcctcgac
    26041 ttcacgtccg gcacgttcaa tcaggcggcg tgcttcatca acttcatcga ggcttgtgac
    26101 catcggcaac agaatattca ggttgcccgt agcggcatta gcacgcagca tcgcccgcac
    26161 ctggatcaag aagatctccg gctgatcgag cgtaatgcga atcccacgcc aacccaggca
    26221 tggattctct tcgctgatcg gcatgtaagg cagctgctta tctgctccga catccagcgt
    26281 acgcaaggtg acgggtttat cattgaacat ttgcagcatc ccctgatact gcgccacctg
    26341 ttcttcttcc gacgggaaac cactttgcag catgaatggg atttcagtgc gataaagacc
    26401 gatgccatca atacggctgc ccagtttttc ttcatgttcc gggcttaaac cagcattgag
    26461 catgactttt atacgctcac cgctttttaa ctgcgcgggt aaattgacgt catcttccgc
    26521 cagacggcta agctcaatct cttcactaat tagccgctga tattcttgca gcagtaccgg
    26581 ctccggatcg accagcaatt caccgcgata gccatcaacg atcagcgtcc tacgatgcag
    26641 caccgaaggc tgaatatccg cgcccatcac ggtagggatc cccagcgcac gtaccatgat
    26701 cgcagcatgg gagttggctg cgccatctcg cacgacaaca ccgactaagc gatcctgggg
    26761 cagctcagca agagttgtcg ctgacagttc atctgccacc agaatgaaac gttccggcca
    26821 ggcgttcggc ccttgattag cgtcatcaag atgaaacagc aatcgctgac ccagcgcacg
    26881 taaatcgcca gcccgctctt tgagatagtt atcgcttagc gcggcaaact gttcggcaaa
    26941 tttttcaatg accgttttta ccgcccactc tgccaccgag cctttatcaa cctcggcaaa
    27001 caattcgcga cgcagccggg tgtccgaaag taggtgcgag taaagatcga aaatagccgc
    27061 cgtttctttt tgtgctccgg cggcaaagcg tttgctgtag cggcgaaact cgtttgccgc
    27121 ttcttccagc gccccggtca gtcgttcgcg ttccagagcc ggatccagcg ttgatgcctg
    27181 atacacctgt tccattaaag gtaacgtggc atcctgccag ccttcggcaa tcgccacacc
    27241 aggtgctgcc ggtaatgcgc ggattcgcgt ctggcgatat tgcccaaaca gggcagtcaa
    27301 ctgcgactgg gaaagaatag ctgccatctg ggtggcaagc gtcaccagga aggattcttc
    27361 actttcgtca tactggcgca actctcgttg ctgtaccacc agtacaccaa gcaactggcg
    27421 acgttgaata attggtacgc ctaaaaacgc gcggaaacgt tcttctttta cggaggggat
    27481 gtatttgaag ctggggtgct tttgcgcatc tgcaaggttt atcggttccg ccagcctgcc
    27541 aaccaggccg acgatccctt catcaaacgc gagcgttaca gtgcgaccgc gtggtttttt
    27601 cagcccccgg gtcgccatca ggtagtaaca acgtcgatca tgatcggcca ggtagaccga
    27661 acagacctcg gtatccatcg caagacagat gtcggtaacc agaatattta acgcctcatt
    27721 caggcgtggt gcgctggcta ccttttcgac tatttcgcgc aggcgagtga gcataattgg
    27781 cgtgacttaa cctcttttac gtcgataagc agatgcgttt tgtggttttg gcgtattttc
    27841 ctgcagtgac atcaccacac tcgcgaactc tttcattacc ctacggtaga catcacgttt
    27901 aaatgacacc acctgtctga ccggatacca gtaacttacc catcgccagc cgtcaaactc
    27961 tggtgtactg ctggtttgca tattgatttc tgcatcgccg ctcaccagct gcaagagaaa
    28021 ccatttttgt ttttggccga tacaaaccgg cttcgtgtcc caacgcacca aacgtttcgg
    28081 taatttgtag cgcaaccagt tacgcgttga agcaaggatt cgaacgtctt tgcggcttaa
    28141 tcctacttct tcaaacaatt cacggtacat cgcctgctct gcggattctc cggggttgat
    28201 tccgccttgc ggaaattgcc aggagtgctg accaaatcgc cgggcccaca ttacctgccc
    28261 ctggcgatta caaatcacga tacctacgtt tgggcggtag ccatcgtcat caatcaccgg
    28321 actacctcaa aataaagctt tatatacgaa tgattgtttc atactccagg aagacggtaa
    28381 accactctct gcagggcatt acacactaat aacaattgaa taactcacag ttatgtgcag
    28441 agttataaac agaggaaggg gtggatagcc gtttttattc accttttctg tggatagagt
    28501 tgtgaagaac tacggaatta ctacgggaaa acccggagca ttctgaataa gcccgatata
    28561 gacattttaa aatattcatt attagtcaat gcattacatg taatttgagt aatgaaaaag
    28621 agtaattcgt gacccagctc acacctctca tttacgggtt ggcgaaagat caaccaatgc
    28681 cgtatttatc cacagaatgt gccactaagt taagcactga accactaaaa actggagttt
    28741 cgtcgcacgt caaggctgta aatggaaaca gtagtggagg tttttcacag ttatcccagc
    28801 tttctgtgga taacatggtg taagatcctg tttattttca gtgaccagat ttggaaaacc
    28861 tattgcagtg ttgcgcaact cgattaccgg cagcctaaaa agcaatataa atcagagaat
    28921 tgaacaacac atgtggaaaa agttacactg cgaatattcg gcacataatt gctgtttgtt
    28981 ttttaaccaa ggtatcatga catgtcccaa cctcgcccac tgctctctcc tcccgaaact
    29041 gaagaacagt tgttagcgca agcacagcaa ctttctggtt atacattggg agaactggcg
    29101 gcacttgccg ggctggttac gccagagaat ttaaaacgcg ataagggctg gattggcgtg
    29161 ttactggaga tctggctagg tgccagcgca gggagtaaac ctgagcaaga ttttgctgct
    29221 ctgggcgtgg aacttaaaac tatccctgtg gatagtcttg gtcgtccgct ggaaacaaca
    29281 ttcgtttgtg ttgccccgtt aacgggtaat agcggggtga cctgggaaac cagccatgtg
    29341 cgccacaagc tcaaacgcgt actgtggata ccggttgaag gcgagcgcag catcccgctg
    29401 gcgcagcgtc gcgtaggatc accgttgctg tggagcccga atgaagagga agaccgacag
    29461 ctacgcgaag actgggaaga attaatggat atgattgttc tcggtcaggt tgagcggatc
    29521 accgctcgtc acggggaata tttacagata agaccgaaag cagcgaatgc gaaagcgctt
    29581 accgaagcca ttggtgcccg gggcgaacgg attctgacgc tgccacgcgg cttttatttg
    29641 aagaagaatt tcaccagtgc actactggcc cgtcattttc tgatccagta gccatcgctt
    29701 tgacctgccg ctttccgggc atataattac cgcttcattt ttttggcagg gctttttaga
    29761 tgttatttgc atggataacc gatcctaacg cctggcttgc gctcggtacg ctgacgctgc
    29821 tggagatcgt tcttgggatc gacaatatta ttttcctttc tctggtggtg gcaaagcttc
    29881 ccacagcaca acgtgctcat gcgcgccgtc tggggttggc gggagccatg gttatgcgtc
    29941 tggcgctgct ggcatcaatc gcctgggtta cgcgcctgac aaatccgctt tttacaatat
    30001 tcagtcagga aatttctgcc cgtgatttga ttctgcttct gggtggcttg ttccttatct
    30061 ggaaagccag caaggaaatc cacgaatcca ttgaaggtga agaagaaggg ctgaaaacac
    30121 gcgtttcatc attcctcggc gctatcgtgc agattatgct gctggatatt atctttagcc
    30181 tcgactcggt gattacggct gtgggtctgt cagatcacct gtttattatg atggcagccg
    30241 tggtgattgc cgtaggcgtg atgatgttcg ccgcgcgctc gattggtgat tttgtcgaac
    30301 gccatccttc ggtaaaaatg ctggcgctct ctttcctgat tctggtgggc tttaccctga
    30361 ttctggaaag tttcgacatc cacgtaccga aaggttacat ctacttcgcg atgttcttct
    30421 ctattgcggt tgaaagcctc aacttgattc gcaacaaaaa gaatccgctc tgatactccg
    30481 tacgctctcc tgcgggaggg cgtactcact ccttttaccc tcacagttta agattttcct
    30541 gctttcaaga tatataacgt cggtttataa acagactatt atcataggta ggccaaatga
    30601 ggataaccgg atgaaaaaat gggcagtaat aatttctgca gtcggactgg cgtttgctgt
    30661 ttccgggtgt tccagtgatt acgtcatggc gaccaaagat ggccgtatga ttttgaccga
    30721 tggaaaacct gaaattgatg atgataccgg gctggtgagt tatcacgatc agcaaggtaa
    30781 cgcgatgcaa attaaccgtg atgatgtttc gcaaattatt gaacgttaac aaataaggtc
    30841 agcatccggc tggccttaag atttttctct ttcccttttc ccttccctct gccattttta
    30901 tattccttat gtcgtgatta taaaaaggaa acggctatgc aatatcaccg tataccccac
    30961 agttcgctgg aagtcagcac gctggggctt ggcacgatga cgtttggtga acagaacagc
    31021 gaagccgacg cccacgcaca actcgactat gccgtcgctc agggcattaa ccttatcgac
    31081 gttgccgaaa tgtacccagt acctccgcgc cccgaaacgc aagggttaac cgaaacctac
    31141 gtcggcaact ggctggcgaa acatggcagc cgcgaaaagt taattatcgc ctccaaagtg
    31201 agcggaccgt cgcgcaataa tgacaagggc atccgcccgg atcaggcgct ggatcggaag
    31261 aatatccgcg aagcgctgca tgacagcctc aagcgcctac agactgatta cctcgatctt
    31321 tatcaggtgc actggccgca gcgcccgacc aactgcttcg gcaaactcgg ttatagctgg
    31381 acggattctg cgcctgcggt ttcgctgctg gatacgctgg acgcactggc agagtaccaa
    31441 cgcgcgggaa aaattcgtta tatcggcgtg tcgaacgaaa ctgcatttgg cgtaatgcgc
    31501 tacctgcatc tggcggacaa acacgatctg ccgcgtattg tcaccattca gaacccttac
    31561 agtctgttaa accgcagttt tgaagtaggt ctggcagaag tcagccagta tgaaggggtc
    31621 gaactgctgg cctattcgtg cctgggtttc ggcacgctga ccgggaaata tctcaatggt
    31681 gcaaaacccg ctggcgcacg taatacgctc tttagtcggt tcacccgcta tagcggtgag
    31741 caaacgcaaa aagccgtcgc ggcgtatgtt gatatcgcca gacgtcatgg cctggaccct
    31801 gctcagatgg cgctcgcgtt tgtacgccgt caaccgtttg ttgccagcac tctgctgggc
    31861 gcaaccacga tggatcagct gaaaactaac atcgaaagtt tgcatctgga gttaagcgaa
    31921 gacgtattag ctgaaattga agcggtgcat caggtttata cttatccggc accataagat
    31981 taacgccggt taaaaccggc gttaaatatt aatgacggcg ctgccagatc cacagcgccg
    32041 ttattgccag cgcaaacagc gcaccgaagc caatgccaat gggcacgacc gggatgccta
    32101 tcattaccgc cagcgagtaa atgcccagca tcaacaacat ggcgctgttt tcgccaaggt
    32161 tttgtactgc aatcgcattc cccgccccga cgcttttttt accccgctcc tgtagcaacg
    32221 cattgagcgg aacgacaaaa aagcccccca tcacgccaat cagcatcaac aaggcatagg
    32281 ctggcagcag ctcgtgttgc agggaaaaaa tcagtaccac cacgccaatc aaaatcccgg
    32341 ctggcataca gcgtgacacg gtttccagcg taactaactt cgctgccgca cctgcgccaa
    32401 ccacgatacc aatcgctacc atcgcgttga gataggtggg cgtagcgtta tcggtaatgc
    32461 ccagcgccac cggtacccac agcaccaaca ggaaacgcag cgtgacaccc gctccccaga
    32521 ataaactggt gcccaccagc gaaaaacgcg tttcaccatt gcgccatagc gaggtgcagg
    32581 cattcaggaa actgcgggtc atgttgatga gattccagga ctgccccgga cgcgccgccg
    32641 ccagtttggg aatgtagata ttggcaacga ccgcaccacc gtaggccagt gcgcatgcgg
    32701 ccagggcgac gaggacatgc cagtcagcca gcacaccacc ggctacggaa ccgagcaaaa
    32761 tcgccgctat ggtagaagct tccattaaac cgttagcttt cactaactta ctacccgtgg
    32821 ttaattcgcc gagaataccg tatttcgccg gtgaataggc tgcagcacca acacccacca
    32881 gcgtatagcc gagaaacgga ttgataccaa agcagatact ggctgcgccc agcagcttca
    32941 ggccgttggc aaacatcatc acccggcctt tggcgaagct atccgccacc tgcccgacaa
    33001 acggcgcaaa aagaatgtaa gcacctacaa acaccatttg caggatgggc tggctccact
    33061 ccggatagaa ctgcgctttc agtaacgcca gagtggcaaa cagtagggca ttatcgccaa
    33121 acgcagagag aaactgcgcc acgataaccg ctttcatccc cttcgaccac aacgaagtgt
    33181 tagtgtgcac tgactcactc atcgtgttgt tccgcttcgt ctacccagct tttcaacgtg
    33241 acaaagtcag gtttgccgct gccaagtaat ggcatctgtt tcagatagcg aatatcgcgc
    33301 ggtacagcaa gctccggcac gccgtgctcg cgggcatact gttgcaactt atcgcgcgtc
    33361 agttcgttat ctgtggtgaa aagcaccagt gcctcgcctt tgctggcatc gctcttaatc
    33421 gcagtggcat ggactttatc tggcgaaaca ccaagtgcca gttgttccac catttccagc
    33481 gacaccattt cgcctgcaat tttggcaaag cgttttgcgc ggccctgaat ctgcacaaag
    33541 ccctgctcgt caaaacgcac aatatcgcca gtgtcatacc agccgcgctc catttcgccg
    33601 cgaacattct cggcggtggg cacttccagt acacctggct tctccacccg cagatagccg
    33661 ttcattatgt tcggcccttt cagttgcagg cgtccgccct cttcgatacc agggaccgac
    33721 aacaggcgcg catccattcc tggtagaata cgccctaccg taccgggttt cgccgccatc
    33781 ggtacgttga tagaaacgac aggcgcgcac tcggttacac catagccttc aaggatgcgc
    33841 aggccaaatt tatcctgcca aagctgtttg gtactttctt gtagtttttc tgcgcctgcc
    33901 accacatagc gtagacgata gaagtcatac gggttggcga aacgcgcgta gtgaccgagg
    33961 aaagtcgagg taccgaacaa cacggtgcaa ctgcggtcat acaccaactc cggcacaatg
    34021 cggtaatgca gcgggcttgg ataaaggaac acttctgcac ctgtaagcag tggcgtaaac
    34081 aggcctaccg tcagcccaaa ggagtgaaac agcggtaatg ccgacataaa gcgatcgttg
    34141 gtggtgaagt cggcaatcgt tttaatctgc tcgacgttcg ccagaatgct tttatggcta
    34201 tggacgacgc cttttggatg gccttcagaa ccggaggtaa agaggatcag cgcctcttct
    34261 tccggctgct gttttacctg cgccaggcgc ggcatcagca aatgagcgaa gatccatact
    34321 ttgtcggcag tggtgacatc tgcttttaaa tcttccagat agacccagcg cacctgagta
    34381 agttgctccg gcagatgcca gagtttgcct ttatcgagaa actggcggga agtgaagatg
    34441 gttttgattt cagccgccgt aatagcactg gtcagccctt ttaccccagc agtgtagttc
    34501 atcattgcgg gaatgcggcg acgcgcgatg gccccaaaaa tcactgccgc actgatgcct
    34561 gcattgggca gcattaagcc gatgcgttcg ccttcaacac tgtatttttc aaggatgcgt
    34621 ccaacaaaca gcgttttcgt aagcaatttg cgataggagt ctggggtaaa gttgacgtct
    34681 tcgacacatt tcttcccggc tccgaagcgg tacattgcac tcagtaaaga ttcgtacaga
    34741 gtttcacgcg ggcgcaccgc catacgcgct tccatcatta tttgatgcag catttcacca
    34801 gcgattttgc gacggtcacg ggcacgcggc gcatccggca tcgccacctg cgttggtggc
    34861 aaaatatgca gagtaatttg cgggaacaag cgacgtttaa ccagaccttt caggcggctg
    34921 aagtgcgtaa gttccgcccc ttcaatacgc acaggaataa ccgttgcacc agacttcgcc
    34981 gcgacaaaac ccgcgccatc gtagattttc atcagcgagc ctgtagtggt gatgcgtcct
    35041 tcagggaaaa tcaccactgg tcggccctgt tccaccagac gtaccagatg tttaatagcc
    35101 ataggttgcg tcgggtcgag aggaacaaag tcgataaatg atttcagcca acgcatatac
    35161 cactgttggc ttattgaggt gtaaacggca aacactggac gcacaggtaa aaacagtcca
    35221 agcaaaatgc catcaataaa agagacgtga ttaggcgtaa ttagaacgcg ctcgcccttc
    35281 agtgcctggg tgtcacccgt aacgcgaacg cgatacaaaa cacggcacaa atttcgaaaa
    35341 aagctaaaaa gcattccaac tccctttgct ctgattcagt aaaagcgaat ggagggagat
    35401 tacacgagat aaagaacgcg agcgacagta aattaggtgc gaaaaaaaac ctgcgcatcc
    35461 gcgcaggttg gtgcaagaga cagggtacga agagcgtacc gaataatctc accaatcaat
    35521 acctctggga tcttgattgt ggtctgcacg acgactcttc gccagcgaga aaacgcaaag
    35581 gaatgaaggg aaatgcaacg aggtgtgtaa attgtcggtt actgttacag attgatgacc
    35641 ggccaaaaaa aacctgcgca tctgcgcagg ctggtgtaat tcatgtgctc aacccgaagt
    35701 tgacttcacc tatcaatacc tctgggatca ccactttagc aacctgaagc caaacgccac
    35761 cagcggtcaa tcgcaacagc atttcgcaaa gtgtaaccaa aggtttgcaa tctctttttt
    35821 tgtcttactt atttgcgttt ggctcacatt cccacgatga aaacacgcca ccccttgaac
    35881 caacgggcgt tttccgtaac actgaaagaa tgtaagcgtt tacccactaa ggtattttca
    35941 tggcgaccat aaaggatgta gcccgactgg caggcgtttc agtcgccacc gtttcccgcg
    36001 tcattaataa ttcacctaaa gccagcgaag cttcccggct ggctgtgcat agtgcaatgg
    36061 agtctcttag ctatcacccg aacgccaacg cccgtgcgct ggcgcagcag accactgaaa
    36121 cggtcggtct gatcgttggt gatgtttccg atccgttttt cggtgcaatg gtgaaagcgg
    36181 tcgaacaggt ggcttatcac accggtaatt tcttattgat tggcaacggt taccacaacg
    36241 aacaaaaaga gcgtcaggct attgagcaac tgatccgcca tcgctgtgct gcgttggtcg
    36301 tccatgccaa aatgatcccg gatgccgatt tagcctcatt aatgaaacaa atgcccggta
    36361 tggtgctgat caaccgtatc ctgcctggct ttgaaaaccg ttgtattgct cttgacgatc
    36421 gttacggtgc ctggctggca acgcgtcatt taattcagca aggtcatacc cgcattggtt
    36481 atctgtgctc taaccactct atttctgacg ccgaagatcg tctgcaaggg tattacgatg
    36541 cccttgctga aagtggtatt gcggccaatg accggctggt gacatttggc gaaccagacg
    36601 aaagcggcgg cgaacaggca atgaccgagc ttttgggacg aggaagaaat ttcactgcgg
    36661 tagcctgtta taacgattca atggcggcgg gtgcgatggg cgttctcaat gataatggta
    36721 ttgatgtacc gggtgagatt tcgttaattg gctttgatga tgtgctggtg tcacgctatg
    36781 tgcgcccgcg cctgaccacc gtgcgttacc caatcgtgac gatggcgacc caggctgccg
    36841 aactggcttt ggcgctggcg gataatcgcc ctctcccgga aattactaat gtctttagtc
    36901 cgacgctggt acgtcgccat tcagtgtcaa ctccgtcgct ggaggcaagt catcatgcaa
    36961 ccagcgacta accgcagtta aagcaattcc agcgccagta attcttcgat ggtctggcga
    37021 cggcgaatca accgcgcctg accattatca aacagaactt ctggtaacag cggacggctg
    37081 ttgtagttgg atgacattga tgcgccatat gcccctgtat catgcagtac cagataatca
    37141 cccgccttca cttccggcaa ggcgcgggtt tcaacatttc ccccttcctg ctgggtaaag
    37201 acatcgcccg attcacataa tggcccggcg acgacggttt ccaccgttgg cgcgtgttcc
    37261 agagaacgac catcagctgc cagggcactg atatggtggt aactaccgta cattgccggg
    37321 cgcatcagat cgttgaaccc agcatcaacc agcacaaagt ggcggctacc catttgtttg
    37381 acgctccgca cctgagtaat taatacgcca gactgcgcta ccaggaagcg acccggttca
    37441 atttccagtt tcacagggtg gcccaaatgg cgggcgattt gctcacgcgc ggcattccac
    37501 agaccataat aatgttcggt atcaaccgcc tcttcaccct gttgataagg aacagaaagc
    37561 ccaccgcccg cagaaatagc ctgtaaatcc tgaccgaatt cgatgacctg acgcaccata
    37621 gcaccacaca cctgttccag atgggcataa tcaacgccag aaccaatgtg catgtgaatg
    37681 ccgaccagct gcagatgatg acgttgtatc acgtccagtg cggcgggcag atcggtgtac
    37741 cagataccgt gcttgctgtt ttcgccaccg gtattggttt tttggctatg tccgtgacca
    37801 aaccccggat taacgcgcag ccatacccga tgccctggcg aaacctggcc cagttggtcg
    37861 agcatatcaa cagaacccgc attcaccgga atttgcaatt cactgacgcg ttcaagcgtc
    37921 gcctgatcga taacatctgc cgtaaaaaca atatcatcgg ggtgcgtttg cggattgtaa
    37981 cccgccgcca acgcacgctc tatttcgcct aacgagacgg aatccacttt cacgccctgc
    38041 tcacgcatta agcgcaaaat atgaatattg gaacaggctt tctgtgcaaa gcgcacaaca
    38101 tcaaactgtt tcagcgctgc aatctgccga cgaataattt gcgcatcgta gacccacacc
    38161 gggcagccaa attcagcggg caaacgcagc agattttcgg cggtgagatc ggtatcggtg
    38221 ctgaacagtg aatgtggcat aacaaactcc agataagtgc ttttttatga ttacgccaca
    38281 tcataaaaag aataaaaaat atcgatttat gtcgagtcta tgcaaaaatg atatggatta
    38341 ccggattgcg agagagcgct aatggccgcc gttaacttac gtcatattga aatttttcat
    38401 gcggtaatga ccgccggaag cctgactgag gcagcacacc tgctacacac ctcacagcca
    38461 accgtcagcc gcgaactggc gcgctttgag aaggtgatcg ggctaaaatt gtttgagcgc
    38521 gtacgtggac gattacatcc taccgtgcaa ggactgcgtc tgtttgaaga agtgcaacga
    38581 tcctggtacg gactggatcg cattgtcagc gccgcagaaa gtctgcgcga gtttcgccag
    38641 ggagaactgt ctattgcctg cctgccggtc ttttcgcaat cttttttacc gcagctcctg
    38701 caaccctttc tggcacgtta tcccgatgtc agcttaaata tcgtgcccca ggaatcaccg
    38761 ctacttgaag agtggctctc ggcccagcgt catgatttag gactcactga gacactccat
    38821 acgcctgcgg gaacagaacg taccgaatta ctctctttag atgaagtgtg tgtgttacct
    38881 ccgggtcatc cgctggcggt aaaaaaggta ttaacgccgg atgattttca gggtgagaac
    38941 tacatcagcc tttcccgtac tgacagctat cgccagttgc tggatcagct atttactgaa
    39001 catcaggtta aacgacgcat gatcgtagaa acccacagcg ccgcgtcagt ctgcgcaatg
    39061 gtacgggcgg gggtaggtgt ttcggtggtt aacccgctca ccgcactgga ttatgcggca
    39121 agcggtttag tggtgcggcg gttcagtatt gcggttccgt tcaccgtcag cctgatccgc
    39181 cccctgcacc gcccgtcatc agcgctggtg caggcgttta gtgagcattt acaagcgggg
    39241 ttaccgaaac tggtcacttc tcttgacgct attttgtcgt cagctacgac agcataaaag
    39301 cgacagcatc ctcggcatgg atcgccgcag tatcaaacac aggcaaaaca ctgcgctctt
    39361 ctggcaccag taaaccaatt tctgtgcagc caaaaatgac gccctgtgcg ccctgttctg
    39421 caaggcgagc aatcacttgc gcataataag cgcgtgacgc ttcggtaaat tgccccagac
    39481 acagttcttc aaaaataatc tgattaattt tcgcccgttc atccgcttca ggaataagac
    39541 aattgatgga aaattgttcc gtcagccgcc cgcgataaaa atcctgttcc atggtgtaac
    39601 gcgtacccag cagcgccaca cgagtcattc cggccccggt aattgcacgt ccggtggcat
    39661 ccgcaatgtg taagaaaggc agagtgcaac gtgactcaat ggcatccgcc actttatgca
    39721 tcgtattggt acataacaca ataccttctg cgcccgcccg ctgtaagcca agcgccgcct
    39781 cagccagaat gtccccggtt ttatcccatt ccccgcgacg ctggcactct tctatttcat
    39841 gaaaatcgac gctatgtagc agcacttgcg cagagtgaag cccaccaagc cgctgtttaa
    39901 tgccttcatt tatcagacga tagtaaggaa tggtggattc ccagctcatt cctcccagca
    39961 aaccaattgt tttcattcct ctctcctgat gtgtgttacc gcaacaaggc tgaataagga
    40021 acgagacaaa cgcctcaacg gccaggtgcc cgatctctat taacgaaaaa agggccggat
    40081 gtacagcaca tccggcccgt gaaatcagac gccgatattt ctcaacttct cgcctgccat
    40141 cagtttgcgt tcgatatgtt ccagcgtgac atttttggtt tccggaatga gccagaaagt
    40201 gatgcccaca aacgcaatgt tcagcgcagt gtagagccag aacgtaccgg cagcgccaat
    40261 gctatcaagc agtgtcagga aggtcgcgcc gataatcata ttcgacaccc agtttgtcgt
    40321 cgtcgaacag gtaataccga aatcgcggca tttcagcggc tgaatttcag agcacaggat
    40381 ccacaccact ggcgcggcgc tcatcgcata accggcaata cacatcatcg tcatgccaac
    40441 agagagccag gacaagccac tggaagccgt accgttatca aactgcatca ggcaatagcc
    40501 cagcaccaga gtgcctaacg ccatcacgct gaaaccaatt ttcagagccg gtttacgacc
    40561 tgctttatct accgtaaaga ccgcaatgaa ggtcgcgaac ataaaggtca gtcccacgac
    40621 cagagtcgca atcatctgtt gttctgtggt cgtaaagccc gccattttga agatacgcgg
    40681 cgcatagtac atgatgatgt tcataccggt aaactgctgc atcgcctgca acaacatacc
    40741 gagaaacaca gcacgacgga cgttacggtt gatcttaaac agtgcccaac cgccttgttt
    40801 taacttcagg ctttcacgaa tttcgttgag ttcttctcgc gctttttccg acgtatcgcg
    40861 cagcatacgc aacacttctt ccgcctcaat atgacgcccc ttttccgcca gccagcgcgg
    40921 gctatttggc aggaagacca ccagaataat cagcaggact gctggtaaag caagaacccc
    40981 caacattgcg cgccagttac cgctataact gaacgctgta tcggataaaa acgccagcac
    41041 gatgccgagt gtgaccatca actggtacat actgatcatc ttaccgcgaa cgttttcact
    41101 tgccatttca gaaagataca gaggagcggt gtaagacgcg atcccgacag caatgcccag
    41161 caccacacga gcggcgatta acatctctac gctggtcgca aaagcggacc ctatagaacc
    41221 gagtacaaac aggatggccc ccgccatcag gctgtattta cgccccaggc ggaacgacag
    41281 ccaaccatta aacagcgcac cgattgctgc gccgagcatc atgctactaa ccacccattc
    41341 ctgcaaacga ctggtcagca caaagtgatc ggtaatgaac ggcaacgctc cggcgattac
    41401 gccgatatca agaccaaata acaatcctgc gaccgcagca gctaccgaaa caaacatatt
    41461 catacgccgc gtatcccgca aagaacgtgg cgttaaagca gattccgtat tgatagtaac
    41521 cattttttcc tgccagcaga gagtaagaca tagtgaaaaa atacgtgaac aattcacaca
    41581 ggtgtcaggt cggaaacagc ataaatatgg attaaattgc tgcggcatgt cgttatgtga
    41641 tggatattcc aattttcaaa ttaagttgaa ttattgagat tattattaac cacctaattt
//
LOCUS       DAPOAV010000035        41021 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.035, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000035 DAPOAV010000000
VERSION     DAPOAV010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 41021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41021
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.035"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            124..732
                     /locus_tag="RN951_002120"
     CDS             124..732
                     /locus_tag="RN951_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX family permuted papain-like enzyme"
                     /protein_id="HDX2527119.1"
                     /translation="MKNRLLILSLLVSVPAFAWQPQTGDIIFQISRSSQSKAIQLATH
                     TDYSHTGMLVIRNKKPYVFEAVGPVKYTPLKQWIAHGEKGKYVVRRVEGGLSVEQQQK
                     LAQTAKRYLGKPYDFSFSWSDDRQYCSEVVWKVYQNALGMRVGEQQKLKEFDLSSPQV
                     QAKLKERYGKNIPLEETVVSPQAVFDAPQLTTVAKEWPLFSW"
     gene            complement(793..1005)
                     /gene="rpmE"
                     /locus_tag="RN951_002121"
     CDS             complement(793..1005)
                     /gene="rpmE"
                     /locus_tag="RN951_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HDX2527120.1"
                     /translation="MKKDIHPKYEEITASCSCGNVMKIRSTVGHDLNLDVCSKCHPFF
                     TGKQRDVATGGRVDRFNKRFNIPGSK"
     gene            1208..3406
                     /gene="priA"
                     /locus_tag="RN951_002122"
     CDS             1208..3406
                     /gene="priA"
                     /locus_tag="RN951_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HDX2527121.1"
                     /translation="MPVAHVALPVPLPRTFDYLLPEGMTVKAGCRVRVPFGKQQERIG
                     IVVSVSDASELPLNELKAVVEVLDSEPVFTHSVWRLLLWAADYYHHPIGDVLFHALPI
                     LLRQGRPAANAPMWYWFATEQGQAVDLNSLKRSPKQQQALAALRQGKIWRDQVATLEF
                     NDAALQALRKKGLCDLASETPEFSDWRTNYAVSGERLRLNTEQATAVGAIHSAADTFS
                     AWLLAGVTGSGKTEVYLSVLENVLAQGKQALVMVPEIGLTPQTIARFRERFNAPVEVL
                     HSGLNDSERLSAWLKAKNGEAAIVIGTRSALFTPFKNLGVIVIDEEHDSSYKQQEGWR
                     YHARDLAVYRAHSEQIPIILGSATPALETLCNVQQKKYRLLRLTRRAGNARPAIQHVL
                     DLKGQKVQAGLAPALITRMRQHLQADNQVILFLNRRGFAPALLCHDCGWIAECPRCDH
                     YYTLHQAQHHLRCHHCDSQRPVPRQCPSCGSTHLVPVGLGTEQLEQTLAPLFPGVPIS
                     RIDRDTTSRKGALEQQLAEVHRGGARILIGTQMLAKGHHFPDVTLVALLDVDGALFSA
                     DFRSAERFAQLYTQVAGRAGRAGKQGEVVLQTHHPEHPLLQTLLYKGYDAFAEQALAE
                     RRMMQLPPWTSHVIVRAEDHNNQHAPLFLQQLRNLILSSPLADEKLWVLGPVPALAPK
                     RGGRWRWQILLQHPSRVRLQHIINGTLALINTIPDSRKVKWVLDVDPIEG"
     gene            3562..4587
                     /gene="cytR"
                     /locus_tag="RN951_002123"
     CDS             3562..4587
                     /gene="cytR"
                     /locus_tag="RN951_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CytR"
                     /protein_id="HDX2527122.1"
                     /translation="MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRV
                     EKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDPFFSEIIRGIEVTAANHGYLVLI
                     GDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
                     LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVD
                     PQYIARGDFTFEAGSKAMQQLLDLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLS
                     IIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHVGSGSRLMDCELIIR
                     GSTRALP"
     gene            4679..5638
                     /gene="ftsN"
                     /locus_tag="RN951_002124"
     CDS             4679..5638
                     /gene="ftsN"
                     /locus_tag="RN951_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsN"
                     /protein_id="HDX2527123.1"
                     /translation="MAQRDYVRRSQPAPSRRKKSTSRKKQRNLPAVSPAMVAIAAAVL
                     VTFIGGLYFITHHKKEESETLQSQKVTGNGLPPKPEERWRYIKELESRQPGVRAPTEP
                     SAGGEVKTPEQLTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQ
                     QLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASSQQPYQDLLQTPAHTT
                     AQSKPQQAAPVARAADAPKPTAEKKDERRWMVQCGSFRGAEQAETVRAQLAFEGFDSK
                     ITTNNGWNRVVIGPVKGKENADSTLNRLKMAGHTNCIRLAAGG"
     gene            5731..6261
                     /gene="hslV"
                     /locus_tag="RN951_002125"
     CDS             5731..6261
                     /gene="hslV"
                     /locus_tag="RN951_002125"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease subunit HslV"
                     /protein_id="HDX2527124.1"
                     /translation="MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVI
                     AGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADET
                     ASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELSAREIAEKALDIAGDIC
                     IYTNHFHTIEELSYKA"
     gene            6271..7602
                     /gene="hslU"
                     /locus_tag="RN951_002126"
     CDS             6271..7602
                     /gene="hslU"
                     /locus_tag="RN951_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019841241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase ATPase subunit"
                     /protein_id="HDX2527125.1"
                     /translation="MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEEL
                     RHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRD
                     LTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFR
                     KKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKI
                     KDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREG
                     VQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQA
                     LTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGA
                     RRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL"
     gene            7669..8595
                     /gene="menA"
                     /locus_tag="RN951_002127"
     CDS             7669..8595
                     /gene="menA"
                     /locus_tag="RN951_002127"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HDX2527126.1"
                     /translation="MTEQQISRTQAWLESLRPKTLPLAFAAIIVGTALAWWQGHFDPL
                     VALLALITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGVITQQEMKRALIIT
                     VVLICLSGLALVAVACHTLADFVGFLILGGLSIIAAITYTVGNRPYGYIGLGDISVLV
                     FFGWLSVMGSWYLQAHTLIPALILPATACGLLATAVLNINNLRDINSDRENGKNTLVV
                     RLGEVNARRYHACLLMGSLVCLALFNLFSLHSLWGWLFLLAAPLLVKQARYVMREMDP
                     VAMRPMLERTVKGALLTNLLFVLGIFLSQWAA"
     gene            8688..9173
                     /gene="rraA"
                     /locus_tag="RN951_002128"
     CDS             8688..9173
                     /gene="rraA"
                     /locus_tag="RN951_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E activity regulator RraA"
                     /protein_id="HDX2527127.1"
                     /translation="MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFED
                     NGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVDDL
                     EELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDI
                     E"
     gene            complement(9258..9503)
                     /gene="zapB"
                     /locus_tag="RN951_002129"
     CDS             complement(9258..9503)
                     /gene="zapB"
                     /locus_tag="RN951_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septal ring assembly protein ZapB"
                     /protein_id="HDX2527128.1"
                     /translation="MTMSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLSQEVQ
                     NAQHQREELERENNHLKEQQNGWQERLQALLGRMEEV"
     gene            9928..10773
                     /gene="glpF"
                     /locus_tag="RN951_002130"
     CDS             9928..10773
                     /gene="glpF"
                     /locus_tag="RN951_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol uptake facilitator protein GlpF"
                     /protein_id="HDX2527129.1"
                     /translation="MSQTSTLKGQCIAEFLGTGLLIFFGVGCVAALKVAGASFGQWEI
                     SVIWGLGVAMAIYLTAGVSGAHLNPAVTIALWLFACFDKRKVIPFIVSQVAGAFCAAA
                     LVYGLYYNLFFDFEQTHHIVRGSVESVDLAGTFSTYPNPHINFVQAFAVEMVITAILM
                     GLILALTDDGNGVPRGPLAPLLIGLLIAVIGASMGPLTGFAMNPARDFGPKVFAWLAG
                     WGNVAFTGGRDIPYFLVPLFGPIVGAIVGAFAYRKLIGRHLPCDICVVEEKETTTPSE
                     QKASL"
     gene            10796..12304
                     /gene="glpK"
                     /locus_tag="RN951_002131"
     CDS             10796..12304
                     /gene="glpK"
                     /locus_tag="RN951_002131"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDX2527130.1"
                     /translation="MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPG
                     WVEHDPMEIWATQSSTLVEVLAKADISSDQIAAIGITNQRETTIVWEKETGKPIYNAI
                     VWQCRRTAEICEHLKRDGLEDYIRSNTGLVIDPYFSGTKVKWILDHVEGSRERARRGE
                     LLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHTLDWDDKMLEVLDIPREMLPEV
                     RRSSEVYGQTNIGGKGGTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNT
                     GEKAVKSENGLLTTIACGPTGEVNYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFA
                     TKVQNTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANHIIRATLESIAYQTRDV
                     LEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGL
                     AVGFWQNLDELQEKAVIEREFRPGIETTERNYRYAGWKKAVKRAMAWEEHDE"
     gene            12439..13449
                     /gene="glpX"
                     /locus_tag="RN951_002132"
     CDS             12439..13449
                     /gene="glpX"
                     /locus_tag="RN951_002132"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphatase"
                     /protein_id="HDX2527131.1"
                     /translation="MRRELAIEFSRVTESAALAGYKWLGRGDKNTADGAAVNAMRIML
                     NQVNIDGTIVIGEGEIDEAPMLYIGEKVGTGRGDAVDIAVDPIEGTRMTAMGQANALA
                     VLAVGDKGCFLNAPDMYMEKLIVGPGAKGTIDLNLPLADNLRNVAAALGKPLSELTVT
                     ILAKPRHDAVIAEMQQLGVRVFAIPDGDVAASILTCMPDSEVDVLYGIGGAPEGVVSA
                     AVIRALDGDMNGRLLARHDVKGDNEENRRIGEQELARCKAMGIEAGKVLRLGDMARSD
                     NVIFSATGITKGDLLEGISRKGNIATTETLLIRGKSRTIRRIQSIHYLDRKDPEMQVH
                     IL"
     gene            13546..14292
                     /gene="fpr"
                     /locus_tag="RN951_002133"
     CDS             13546..14292
                     /gene="fpr"
                     /locus_tag="RN951_002133"
                     /EC_number="1.18.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin--NADP(+) reductase"
                     /protein_id="HDX2527132.1"
                     /translation="MADWVTGKVTKVQNWTDALFSLTVHAPVLPFTAGQFTKLGLEID
                     GERVQRAYSYVNSPDNPDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDE
                     VPHCETLWMLATGTAIGPYLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEK
                     RYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMV
                     RDTQQLLKETRQMTKHLRRRPGHMTAEHYW"
     gene            complement(14297..14725)
                     /gene="uspD"
                     /locus_tag="RN951_002134"
     CDS             complement(14297..14725)
                     /gene="uspD"
                     /locus_tag="RN951_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspD"
                     /protein_id="HDX2527133.1"
                     /translation="MAYKHIGVAISGNEEDALLVNKALELARHNDAHLTLIHIDDGLS
                     ELYPGIYFPATEDILQLLKNKSDNKLYKLTKNIQWPKTKLRIERGEMPETLLEIMQKE
                     QCDLLVCGHHHSFINRLMPAYRGMINKMSADLLIVPFIDK"
     gene            complement(14752..15051)
                     /locus_tag="RN951_002135"
     CDS             complement(14752..15051)
                     /locus_tag="RN951_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF406 domain-containing protein"
                     /protein_id="HDX2527134.1"
                     /translation="MKDVVDKCSTKGCAIDIGTVIDNDNCTSKFSRFFATREEAESFM
                     TKLKELAAATSSADEGASVAYKIKDLEGQVELDAAFTFSCQAEMIIFELSLRSLA"
     gene            complement(15263..15703)
                     /locus_tag="RN951_002136"
     CDS             complement(15263..15703)
                     /locus_tag="RN951_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HDX2527135.1"
                     /translation="MTIQQWLFSFKGRIGRRDFWIWIGLWFAGMLVLFSLAGKNLLDI
                     QTAAFCLVCLLWPTAAVTVKRLHDRGRSGAWAFLMIVAWMLLAGNWAILPGVWQWAVG
                     RFVPTLILVMMLIDLGAFVGTQGENKYGKDTQDVKYKADNKSSN"
     gene            15804..16403
                     /locus_tag="RN951_002137"
     CDS             15804..16403
                     /locus_tag="RN951_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiQ family protein"
                     /protein_id="HDX2527136.1"
                     /translation="MKPGCTLFFLLCSALTVTTAAHAQTPDTATTAPYLLAGAPTFDL
                     SISQFREDFNSQNPSLPLNEFRAIDSSPDKANLTRAASKINENLYASTALERGTLKIK
                     SIQMTWLPIQGPEQKAAKAKAQEYMAAVIRTLTPLMTKTQSQKKLQSLLTAGKNKRYY
                     TETEGALRYVVADNGEKGLTFAVEPIKLALSESLEGLNK"
     gene            16511..17278
                     /gene="tpiA"
                     /locus_tag="RN951_002138"
     CDS             16511..17278
                     /gene="tpiA"
                     /locus_tag="RN951_002138"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HDX2527137.1"
                     /translation="MRHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPE
                     MYIDMAKREAEGSHIMLGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYH
                     KESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFE
                     GAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKVDANIAEQVIIQYGGSVNASNA
                     AELFAQPDIDGALVGGASLKAEAFAVIVKAAEAAKQA"
     gene            complement(17333..18088)
                     /gene="cdh"
                     /locus_tag="RN951_002139"
     CDS             complement(17333..18088)
                     /gene="cdh"
                     /locus_tag="RN951_002139"
                     /EC_number="3.6.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol diphosphatase"
                     /protein_id="HDX2527138.1"
                     /translation="MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEECLP
                     NQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMPTYRINGTESPLLTDPSTPNFFW
                     LAWQARDFMSKKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVRKQLDNNLAN
                     ISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGRYGLAMVRQS
                     DNSFVLLATQRNLLTLNRASAEEIQDHQCEILR"
     gene            complement(18195..19184)
                     /gene="sbp"
                     /locus_tag="RN951_002140"
     CDS             complement(18195..19184)
                     /gene="sbp"
                     /locus_tag="RN951_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter
                     substrate-binding protein Sbp"
                     /protein_id="HDX2527139.1"
                     /translation="MNKWGVGLTFLLAATSVMAKDIQLLNVSYDPTRELYEQYNKAFS
                     AHWKQQTGDNVVIRQSHGGSGKQATSVINGIEADVVTLALAYDVDAIAERGRIDKEWI
                     KRLPDNSAPYTSTIVFLVRKGNPKQIHDWNDLIKPGVSVITPNPKSSGGARWNYLAAW
                     GYALHHNNNDQAKAQDFIRALYKNVEVLDSGARGSTNTFVERGIGDVLIAWENEALLA
                     ANELGKDKFEIVTPSESILAEPTVSVVDKVVEKKGTKEVAEAYLKYLYSPEGQEIAAK
                     NYYRPRDAEVAKKYENAFPKLKLFTIDEEFGGWTKAQKEHFANGGTFDQISKR"
     gene            complement(19504..20466)
                     /gene="pfkA"
                     /locus_tag="RN951_002141"
     CDS             complement(19504..20466)
                     /gene="pfkA"
                     /locus_tag="RN951_002141"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014072359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDX2527140.1"
                     /translation="MIKKIGVLTSGGDAPGMNAAIRGVVRSALTEGLEVMGIYDGYLG
                     LYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIG
                     GDGSYMGAMRLTEMGFPCIGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSS
                     HQRISVVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVNEIKAGIAKGKKHAI
                     VAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLL
                     LAGYGGRCVGIQNEQLVHHDIIDAIENMKRPFKGDWLDCAKKLY"
     gene            complement(20647..21549)
                     /gene="fieF"
                     /locus_tag="RN951_002142"
     CDS             complement(20647..21549)
                     /gene="fieF"
                     /locus_tag="RN951_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312867.1"
                     /note="FieF, a metal efflux transporter, is a member of
                     the CDF (cation diffusion facilitator) family of
                     transporters; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family cation-efflux transporter FieF"
                     /protein_id="HDX2527141.1"
                     /translation="MNQSYGRLVSRAAIAATAMASLLLLIKIFAWWYTGSVSILAALV
                     DSLVDIGASLTNLLVVRYSLQPADDNHSFGHGKAESLAALAQSMFISGSALFLFLTGI
                     QHLISPTPMTDPGVGVIVTIVALICTIILVSFQRWVVRRTQSQAVRADMLHYQSDVMM
                     NGAILLALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDEERQEI
                     IDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDSLPLVQAHMVADQVEQAILRRFP
                     GSDVIIHQDPCSVVPREGKRSMLS"
     gene            complement(21699..22199)
                     /gene="cpxP"
                     /locus_tag="RN951_002143"
     CDS             complement(21699..22199)
                     /gene="cpxP"
                     /locus_tag="RN951_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell-envelope stress modulator CpxP"
                     /protein_id="HDX2527142.1"
                     /translation="MRIVTAAVMASTLAVSSLSHAAEVGSGDNWHPGEELTQRSTQSH
                     MFDGISLTEHQRQQMRDLMQQARHEQPPVNVSELETMHRLVTAENFDENAVRAQAEKM
                     ANEQIARQVEMAKVRNQMYRLLTPEQQAVLNEKHQQRMEQLRDVTQWQKSSSLKLLSS
                     SNSRSQ"
     gene            22349..23047
                     /gene="cpxR"
                     /locus_tag="RN951_002144"
     CDS             22349..23047
                     /gene="cpxR"
                     /locus_tag="RN951_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response regulator transcription
                     factor CpxR"
                     /protein_id="HDX2527143.1"
                     /translation="MNKILLVDDDRELTSLLKELLEMEGFNVIVAHDGEQALDLLDDS
                     IDLLLLDVMMPKKNGIDTLKALRQTHQTPVIMLTARGSELDRVLGLELGADDYLPKPF
                     NDRELVARIRAILRRSHWSEQQQNNDNGSPTLEVDALVLNPGRQEASFDGQTLELTGT
                     EFTLLYLLAQHLGQVVSREHLSQEVLGKRLTPFDRAIDMHISNLRRKLPDRKDGHPWF
                     KTLRGRGYLMVSAS"
     gene            23044..24417
                     /gene="cpxA"
                     /locus_tag="RN951_002145"
     CDS             23044..24417
                     /gene="cpxA"
                     /locus_tag="RN951_002145"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress sensor histidine kinase CpxA"
                     /protein_id="HDX2527144.1"
                     /translation="MIGSLTARIFAIFWLTLALVLMLVLMLPKLDSRQMTELLDSEQR
                     QGLMIEQHVEAELANDPPNDLMWWRRLFRAIDKWAPPGQRLLLVTTEGRVIGAERSEM
                     QIIRNFIGQADNADHPQKKKYGRVELVGPFSVRDGEDNYQLYLIRPASSSQSDFINLL
                     FDRPLLLLIVTMLVSTPLLLWLAWSLAKPARKLKNAADEVAQGNLRQHPELEAGPQEF
                     LAAGASFNQMVTALERMMTSQQRLLSDISHELRTPLTRLQLGTALLRRRSGESKELER
                     IETEAQRLDSMINDLLVMSRNQQKNALVSETIKANQLWSEVLDNAAFEAEQMGKSLTV
                     NFPPGPWPLYGNPNALESALENIVRNALRYSHTKIEVGFAVDKDGITITVDDDGPGVS
                     PEDREQIFRPFYRTDEARDRESGGTGLGLAIVETAIQQHRGWVKAEDSPLGGLRLVIW
                     LPLYKRS"
     gene            complement(24523..25197)
                     /gene="yiiM"
                     /locus_tag="RN951_002146"
     CDS             complement(24523..25197)
                     /gene="yiiM"
                     /locus_tag="RN951_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418346.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-N-hydroxylaminopurine resistance protein"
                     /protein_id="HDX2527145.1"
                     /translation="MRYPVDVYTGKIQAYPEGKPSAIAKIQVDGELMLTELGLEGDEQ
                     AEKKVHGGPDRALCHYPREHYLYWAREFPEQAELFVAPAFGENLSTDGLTESNVYMGD
                     IFRWGEALIQVSQPRSPCYKLNYHFDISDIAQLMQNTGKVGWLYSVIAPGKVSADAPL
                     ELVSRVSDVTVQEAAAIAWHMPFDDDQYHRLLSAAGLSKSWTRTMQKRRLSGKIEDFS
                     RRLWGK"
     gene            complement(25346..26329)
                     /gene="kdgT"
                     /locus_tag="RN951_002147"
     CDS             complement(25346..26329)
                     /gene="kdgT"
                     /locus_tag="RN951_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate transporter"
                     /protein_id="HDX2527146.1"
                     /translation="MQIKRSIEKIPGGMMLVPLFLGALCHTFSPGAGKYFGSFTNGMI
                     TGTVPILAVWFFCMGASIKLSATGTVLRKSGTLVVTKIAVAWVVAAIASRIIPEHGVE
                     VGFFAGLSTLALVAAMDMTNGGLYASIMQQYGTKEEAGAFVLMSLESGPLMTMIILGT
                     AGIASFEPHVFVGAVLPFLVGFALGNLDPELREFFSKAVQTLIPFFAFALGNTIDLTV
                     IAQTGLLGILLGVAVIIVTGIPLIIADKLIGGGDGTAGIAASSSAGAAVATPVLIAEM
                     VPAFKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKARAAKIEILGTVK"
     gene            complement(26589..27209)
                     /gene="sodA"
                     /locus_tag="RN951_002148"
     CDS             complement(26589..27209)
                     /gene="sodA"
                     /locus_tag="RN951_002148"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Mn]"
                     /protein_id="HDX2527147.1"
                     /translation="MSYTLPSLPYAYDALEPHFDKQTMEIHHTKHHQTYVNNANAALE
                     SLPEFANLPVEELITKLDQLPADKKTVLRNNAGGHANHSLFWKGLKKGTTLQGDLKAA
                     IERDFGSVDNFKAEFEKAAASRFGSGWAWLVLKGDKLAVVSTANQDSPLMGEAISGAS
                     GFPIMGLDVWEHAYYLKFQNRRPDYIKEFWNVVNWDEAAARFAAKK"
     gene            27494..28528
                     /gene="rhaT"
                     /locus_tag="RN951_002149"
     CDS             27494..28528
                     /gene="rhaT"
                     /locus_tag="RN951_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose/proton symporter RhaT"
                     /protein_id="HDX2527148.1"
                     /translation="MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIV
                     SWIILPWAISALLLPNFWAYYSSFSLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMG
                     IGIAIGITLIVGTLMTPIINGNFDVLISTEGGRMTLLGVLVALIGVGIVTRAGQLKER
                     KMGIKAEEFNLKKGLVLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYV
                     VIMGGGAIINLGFCFIRLAKVKDLSLKADFSLAKSLIIHNVLLSTLGGLMWYLQFFFY
                     AWGHARIPAQYDYISWMLHMSFYVLCGGIVGLVLKEWNNAGRRPVTVLSLGCVVIIVA
                     ANIVGIGMAN"
     gene            complement(28525..29391)
                     /gene="rhaR"
                     /locus_tag="RN951_002150"
     CDS             complement(28525..29391)
                     /gene="rhaR"
                     /locus_tag="RN951_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaR"
                     /protein_id="HDX2527149.1"
                     /translation="MAEVATVAHQLKLLKDDFFASDQQAVAVADRYPQDVFAEHTHDF
                     CELVIVWRGNGLHVLNDRPYRITRGDLFYIHADDKHSYASVNDLVLQNIIYCPERLKL
                     NLDWQGAIPGFNASAGQPHWRLGSMGMAQARQVIGQLEHESSQHVPFANEMAELLFGQ
                     LVMLLNRHRYTSDSLPPTSSETLLDKLITRLAASLKSPFALDKFCDEASCSERVLRQQ
                     FRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMT
                     PSQWRHLNSQKD"
     gene            complement(29447..30283)
                     /gene="rhaS"
                     /locus_tag="RN951_002151"
     CDS             complement(29447..30283)
                     /gene="rhaS"
                     /locus_tag="RN951_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaS"
                     /protein_id="HDX2527150.1"
                     /translation="MTVLHSVDFFPSGNASVAIEPRLPQADFPEHHHDFHEIVIVEHG
                     TGIHVFNGQPYTITGGTVCFVRDHDRHLYEHTDNLCLTNVLYRSPDRFQFLAGLNQLL
                     PQELDGQYPSHWRVNHSVLQQVRQLVAQMEQQEGENDLPSTASREILFMQLLLLLRKS
                     SLQENLENSASRLNLLLAWLEDHFADEVNWDAVADQFSLSLRTLHRQLKQQTGLTPQR
                     YLNRLRLMKARHLLRHSEASVTDIAYRCGFSDSNHFSTLFRREFNWSPRDIRQGRDGF
                     LQ"
     gene            30571..32040
                     /gene="rhaB"
                     /locus_tag="RN951_002152"
     CDS             30571..32040
                     /gene="rhaB"
                     /locus_tag="RN951_002152"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HDX2527151.1"
                     /translation="MTFRNCVAVDLGASSGRVMLARYERECRSLTLREIHRFNNGLHS
                     QNGYVTWDVDSLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDQQGQRVGLPVAY
                     RDSRTNGLMAQAQQQLGKRDIYQRSGIQFLPFNTLYQLRALTEQQPELIPHIAHALLM
                     PDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIG
                     HWICPQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTA
                     LAANITNEGGAEGRYRVLKNIMGLWLLQRVLQEQQINDLPALISATQALPACRFIINP
                     NDDRFINPETMCSEIQAACRETAQPIPESDAELARCIFDSLALLYADVLHELAQLRGE
                     DFSQLHIVGGGCQNTLLNQLCADACGIRVIAGPVEASTLGNIGIQLMTLDELNNVDDF
                     RQVVSTTANLTTFTPNPDSEIAHYVAQIHSTRQTKELCA"
     gene            32037..33296
                     /gene="rhaA"
                     /locus_tag="RN951_002153"
     CDS             32037..33296
                     /gene="rhaA"
                     /locus_tag="RN951_002153"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HDX2527152.1"
                     /translation="MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDD
                     VSGFENPEGSLTGGIQATGNYPGKARNASELRADLEQAMRLIPGPKRLNLHAIYLESD
                     TPVSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDSIRQFWID
                     HCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLNP
                     AHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAA
                     MLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDRVHIGLDFFDASINR
                     IAAWVIGTRNMKKALLRALLEPTAELRKLEAAGDYTARLALLEEQKSLPWQAVWEMYC
                     QRHDTPAGSEWLESVRAYEKEILSRRG"
     gene            33747..34571
                     /gene="rhaD"
                     /locus_tag="RN951_002154"
     CDS             33747..34571
                     /gene="rhaD"
                     /locus_tag="RN951_002154"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HDX2527153.1"
                     /translation="MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTLRLDDADIAP
                     YHDNFHQQPRYIPLSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGIVKVDSDGAGY
                     HILWGLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAV
                     FTRQLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSG
                     PTLDETFGLIDTAEKSAQVLVKVYSMGGMKQTISREELIALGKRFGVTPLASALAL"
     gene            34581..34895
                     /gene="rhaM"
                     /locus_tag="RN951_002155"
     CDS             34581..34895
                     /gene="rhaM"
                     /locus_tag="RN951_002155"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HDX2527154.1"
                     /translation="MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIY
                     LDKARNLLFAMVEIESEERWNAVASTDVCQRWWKYMTDVMPANPDNSPVSSELQEVFY
                     LP"
     gene            35196..35642
                     /locus_tag="RN951_002156"
     CDS             35196..35642
                     /locus_tag="RN951_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HDX2527155.1"
                     /translation="MAALTASCIDLNIQGNGAYSVLKQLATIALQNGFITDSHQFLQT
                     LLLREKMHSTGFGSGVAVPHGKSACVKQPFVLFARKAQAIDWKASDGEDVNCWICLGV
                     PQSGEEDQVKIIGTLCRKIIHKEFIHQLQQGDTDQVLALLNQTLSS"
     gene            35653..37104
                     /locus_tag="RN951_002157"
     CDS             35653..37104
                     /locus_tag="RN951_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418335.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIBC"
                     /protein_id="HDX2527156.1"
                     /translation="MESSLRIVAITNCPAGIAHTYMVAEALEQKARSLGHTIKVETQG
                     SSGVENRLSSEEIAAADYVILATGRGLSGDDRARFAGKKVYEIAISQALKNIDQIFSE
                     LPTNSQLFAADSGVKLGKQEVQSGSVMSHLIAGVSAALPFVIGGGILVALANMLVQFG
                     LPYTDMSKGAPSFTWVVESIGYLGFTFMIPIMGAYIASSIADKPAFAPAFLVCYLAND
                     KALLGTQSGAGFLGAVVLGLAIGYFVFWFRKVRLGKALQPLLGSMLIPFVTLLVFGVL
                     TYYVIGPVMSDLMGGLLHFLNTIPPSMKFAAAFLVGAMLAFDMGGPINKTAWFFCFSL
                     LEKHIYDWYAIVGVVALMPPVAAGLATFIAPKLFTRQEKEAASSAIVVGATVATEPAI
                     PYALAAPLPMITANTLAGGITGVLVIAFGIKRLAPGLGIFDPLIGLMSPVGSFYLVLA
                     IGLALNISFIIVLKGLWLRRKAKAAQQELVHEH"
     gene            37094..38164
                     /locus_tag="RN951_002158"
     CDS             37094..38164
                     /locus_tag="RN951_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDX2527157.1"
                     /translation="MNIELLQQLCEASAVSGDEQEVRDILINTLEPCVNEITFDGLGS
                     FVARKGNKGPKVAVVGHMDEVGFMVTHIDESGFLRFTTIGGWWNQSMLNHRVTIRTHK
                     GVKIPGVIGSVAPHALTEKQKQQPLSFDEMFIDIGANSREEVEKRGVEIGNFISPEAN
                     FACWGEDKVVGKALDNRIGCAMMAELLQTVNNPEITLYGVGSVEEEVGLRGAQTSAEH
                     IKPDVVIVLDTAVAGDVPGIDNIKYPLKLGQGPGLMLFDKRYFPNQKLVAVLKSCAAH
                     NDLPLQFSTMKTGATDGGRYNVMGGGRPVVALCLPTRYLHANSGMISKADYEALLTLI
                     RGFLTTLTAEKVNAFSQFRQVD"
     gene            38164..39912
                     /locus_tag="RN951_002159"
     CDS             38164..39912
                     /locus_tag="RN951_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative frv operon regulatory protein"
                     /protein_id="HDX2527158.1"
                     /translation="MLNERQLKIVDLLEQQPRTPGELAQQTGVSGRTILRDIDYLNFT
                     LNGKARIFASGSAGYQLEIFERRSFFQLLQKHDNDDRLLALLLLNTFTPRAQLASALN
                     LPETWVAERLPRLKQRYERTCCLASRPGLGHFIDETEEKRVILLANLLRKDPFLIPLA
                     GITRDNLQHLSTACDNQHRWPLMQGDYLSSLILAIYALRNQLTDEWPQYPGDEIKQIV
                     EHSGLFLGDNAVRTLTGLIEKQHQQAQVISADNVQGLLQRVPGIASLNIIDAQLVENI
                     TGHLLRCLAAPVWIAEHRQSSMNNLKAAWPAAFDMSLHFITLLREQLDIPLFDSDLIG
                     LYFACALERHQNERQPIILLSDQNAIATINQLAIERDVLNCRVIIARSLSELVAIREE
                     IEPLLIINNSHYLLDDAVNNYITVKNIITAAGIEQIKHFLATAFIRQQPERFFSAPGS
                     FHYSNVRGESWQHITRQICAQLVAQHHITADEAQRIIAREGEGENLIVNRLAIPHCWS
                     EQERRFRGFFITLAQPVEVNNEVINHVLIACAAADARHELKIFSYLASILCQHPAEII
                     AGLTGYEAFMELLHKG"
     gene            complement(39962..41017)
                     /locus_tag="RN951_002160"
     CDS             complement(39962..41017)
                     /locus_tag="RN951_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiG family protein"
                     /protein_id="HDX2527159.1"
                     /translation="MKRNLLSSAIIVAIMSLGLTGCDDKKAETETLPPANSQPAAPAP
                     EAKPTEAPVAKAEAKPETPAQPVVDEQAVFDEKMDVYIKCYNKLQIPVQRSLARYADW
                     LKDFKQGPTGEERTVYGIYGISESNLAECEKGVKSAVALTPALQPIDGVAVSYIDAAV
                     ALGNTINEMDKYYTQENYKDDAFAKGKTLHQTFLKNLEAFEPVAESYHAAIQEINDKR
                     QLAELKNIEEREGKTFHYYSLAVMISAKQINNLISQDKFDAEAAMKKVSELETLVAQA
                     KEADKGGMNFSFINSAGQYQLEAKKYVRRIRDKVPYSDWDKEQLQDANSSWMVEDSFP
                     RALREYNEMVDDYNSLR"
BASE COUNT         9983 a        10631 c        10607 g         9800 t
ORIGIN      
        1 catattgcaa tttattgaat ttgcacgaac ttgtaggccg gataaggcgt tcacgccgca
       61 tccggcataa acaacgagca cgttgtctgc gacccaccgc tttttataca tggacgttta
      121 actatgaaaa acaggctgct gatcctcagc ctgctggttt ctgtacctgc ctttgcctgg
      181 cagccacaaa ccggcgacat catctttcag atctctcgct catcgcaaag taaagcgatc
      241 caactggcga cccataccga ttatagccac accggtatgc tggtgatacg caacaaaaag
      301 ccctacgttt ttgaagcagt cggcccggtg aaatacaccc cgctcaagca gtggatcgcc
      361 catggtgaaa agggcaaata cgttgttcgc cgcgttgaag gcggactgag tgttgaacaa
      421 cagcaaaaac tggcgcaaac ggcaaaacgt tatctcggta aaccgtatga tttcagcttc
      481 tcatggagcg acgatcgcca gtactgttcg gaagtggtgt ggaaggttta ccagaacgcg
      541 ctgggaatgc gcgtgggcga gcagcagaag ttgaaagagt tcgacctgag cagcccacaa
      601 gttcaggcaa agctcaaaga acgttacggc aagaatattc cgcttgagga aacggtggtc
      661 tcgccacaag ccgttttcga tgcgccacaa ctcaccacgg tcgccaaaga atggccgctg
      721 ttttcgtggt aatacgacca aaattcaggc acaaaaaaag cgccgtgcgg cgcttttttc
      781 ggaaatccgg tcttatttgc tgcccgggat gttgaaacgc ttgttgaagc ggtcaacacg
      841 gccaccggta gcaacatcac gctgtttgcc agtgaagaac gggtggcact tgctgcacac
      901 gtcgaggttc aggtcatgac caacggtgga gcggattttc attacgttac cgcaagagca
      961 gctagcagta atttcttcgt atttcgggtg aatatctttt ttcatgggaa aacctcggtt
     1021 taaggccgcg tcgctcttcc agccctaacg ccagacacca cgcgatgtta aaagtatagc
     1081 ttcaatacga tcatttcgta cgaaggcgcg aaatcataca gaaattaacc agcgtatgca
     1141 aactgatccg cactcttcta cggcaatgtg tatactaacc caccgaattt caagtcagga
     1201 tgatgctatg cccgttgccc acgttgcctt gcccgttccg cttcctcgta cctttgacta
     1261 tctgctgcca gaaggcatga cggttaaagc tgggtgtcgc gtgcgcgtgc cgtttggcaa
     1321 acagcaggag cgcatcggga ttgtggtatc agttagcgat gccagcgaac tgccgctcaa
     1381 tgagctaaaa gcggtagtcg aagtgctgga tagtgagccg gtgtttactc actccgtctg
     1441 gcgattgctg ctatgggcgg cagattacta tcatcatccg attggcgatg tgctgtttca
     1501 tgccttgccg attttactac gccaggggcg gcctgcggcg aacgcgccga tgtggtactg
     1561 gtttgccact gaacaaggcc aggcggtgga tctgaacagc ctgaaacgct cccccaagca
     1621 acaacaggcg ctggcggcgt tacggcaagg caaaatctgg cgcgaccagg tcgccacgct
     1681 cgaatttaat gatgccgcgt tgcaggcgct acgcaaaaaa ggtctgtgtg atttagcaag
     1741 tgaaacacca gagtttagcg actggcgaac gaactatgcc gtttctggtg agcggttgcg
     1801 attgaatacc gaacaggcca ccgccgttgg cgcaattcat agcgcggcag atactttttc
     1861 tgcctggctg ctggcgggcg ttaccggttc cggtaaaacg gaggtttatc tcagcgtact
     1921 ggaaaacgtg ctcgctcagg gcaaacaggc gctggtgatg gtgccggaaa tcggcctgac
     1981 accgcaaact atcgcccgtt ttcgtgaacg ttttaatgcc cccgtggaag ttctgcattc
     2041 cggcctgaac gacagcgagc gtctttcggc gtggctgaaa gcgaaaaatg gtgaggcggc
     2101 gattgtgatc ggcacccgct ccgcgctgtt tacgccgttt aaaaatctcg gcgtgattgt
     2161 cattgatgaa gagcacgaca gctcctacaa gcagcaggaa ggctggcgct atcatgcccg
     2221 cgacctggcg gtgtatcgtg cgcacagcga gcaaatcccg attattcttg gctccgcaac
     2281 gcccgcgctg gaaacgttat gcaacgtcca gcagaaaaaa taccgcctgc tgcgcctgac
     2341 ccgtcgggca gggaatgcgc gtccggcaat tcaacatgtg ctggatttaa aaggtcagaa
     2401 ggtgcaggca ggtctggctc cggcgttaat cactcgtatg cgccagcatt tacaggctga
     2461 taaccaggtc attctctttc ttaaccgccg tggctttgcg cctgcactgc tgtgccacga
     2521 ctgtggctgg attgccgaat gcccacgttg cgatcactac tacacgctgc atcaggcgca
     2581 gcaccatctg cgctgccacc actgtgacag tcagcgtccg gtgccgcgcc agtgcccttc
     2641 ctgcggttcc acgcacctgg tccccgtggg gctgggcacc gaacagcttg aacagacgct
     2701 cgcgccgttg ttccccggcg tgcccatttc tcgtatcgac cgcgatacca ccagccgcaa
     2761 aggggcgctg gaacagcaac tggcagaagt acatcgcggc ggcgcgcgga ttttgattgg
     2821 tacacaaatg ctggcgaaag gtcaccattt cccggatgtg acgctggttg cattactgga
     2881 cgtggacggc gcgctgtttt ctgccgattt tcgctcggca gagcgtttcg ctcagcttta
     2941 cacccaggtc gccggtcgtg ccgggcgtgc gggtaaacag ggcgaagtgg tgctgcaaac
     3001 gcaccatccg gaacatcctc tgttgcaaac gttgctctat aaaggctacg acgcctttgc
     3061 cgaacaggcg ctggctgagc ggcgaatgat gcagctaccg ccgtggacca gccatgtgat
     3121 tgtgcgtgcg gaagatcata acaatcagca cgcgccattg ttcctgcaac aactgcgtaa
     3181 tctgatcctc tccagcccac tggcagacga gaaactgtgg gttctcggtc cggttccggc
     3241 tctggcacct aaacgtggcg gtcgctggcg ctggcagata ttgttgcagc acccttcccg
     3301 cgtgcgcttg caacacatca ttaacggtac gctggcgctc atcaatacaa taccggattc
     3361 ccgtaaggtg aaatgggtgc tggatgttga tccgattgag ggttaaaccg ctcacgatgc
     3421 gaggcggatc gaaaaattca atattcatca cacttttcat gaaaattctg taaccgtttt
     3481 cacgcgctat ctgctaaaaa tgttgccgat gtgaagtaaa catggatgta gtacgcctga
     3541 cgtgccaggc gaggagtgag tgtgaaagcg aagaagcagg aaactgccgc gaccatgaaa
     3601 gacgttgccc tcaaggcaaa agtctctaca gcgaccgtct cccgagcatt aatgaatccc
     3661 gataaagtct cccaggccac ccgtaatcgg gttgaaaaag cggcccggga agtgggttat
     3721 ttaccgcagc ctatggggcg caacgtcaag cgtaatgaat cccgcaccat tctggtgatt
     3781 gtcccggata tctgcgatcc cttctttagc gaaattattc gcggtatcga agttacggcg
     3841 gcaaatcacg gatatctggt gctgattggc gactgtgcgc atcaaaatca gcaggaaaaa
     3901 acctttatcg atttgatcat caccaagcaa attgatggca tgttgttgct gggttcaagg
     3961 ctgccgtttg atgccagcat tgaggaacag cgtaatctgc cgccgatggt gatggcgaac
     4021 gaatttgcac cggagctgga gctgcctaca gttcatatcg acaatctgac cgccgcattt
     4081 gatgcagtaa attatttata tgagcaaggg cataaacgga ttggctgtat agccggtccc
     4141 gaagagatgc cgctgtgtca ctaccgcctg caaggctatg ttcaggcgct gcgtcgctgc
     4201 ggcattatgg ttgatccgca atacatcgcc cgtggcgact tcaccttcga agccggaagc
     4261 aaagcgatgc agcagctgct tgatcttcca caaccgccta ctgctgtctt ctgccatagc
     4321 gatgtgatgg cgctcggcgc actttctcag gcaaaacgcc aggggctgaa agtcccggaa
     4381 gacctttcca taatcggttt tgataacatc gacctgacgc aattttgtga tccgccgctg
     4441 acaaccatcg cgcagccgcg ttacgaaatc ggtcgggaag ctatgctgtt attgcttgat
     4501 caaatgcagg ggcaacacgt tggcagtggc tctcgtttaa tggactgcga acttatcatc
     4561 cggggatcaa cacgcgcgtt accttaaagt aaacctttaa gactgccgtg actggtcaaa
     4621 ggcccgccgc ttaagtaaca tggcgggctg acgaacgaat aaatacagcg aaacgatagt
     4681 ggcacaacga gattatgtac gccgcagcca accggcacct tcgcggcgaa aaaagagcac
     4741 ctcacggaaa aagcaacgaa atctgcctgc ggtttctccc gctatggtcg ctattgctgc
     4801 cgccgttctt gtgaccttta tcggtggtct gtacttcatt acgcatcaca agaaagaaga
     4861 gtccgagacg ctgcaaagcc agaaagtgac cggaaacgga ctaccaccaa aaccagaaga
     4921 acgctggcgc tacattaaag agctggaaag tcgccagccg ggagtgcgtg cgcccacaga
     4981 accttctgcc ggtggtgaag tgaaaacgcc ggagcaactg acaccagaac aacgtcagct
     5041 tcttgaacaa atgcaggctg atatgcgcca gcagccaacg cagctggttg aagttccgtg
     5101 gaatgaacag acgccggaac agcgtcagca aacgctacag cgccaacgtc aggcgcagca
     5161 attagcggaa cagcaacgcc tggctcagca gtcgcgtacg actgaacaaa gctggcagca
     5221 gcagacgcgt acgtcgcaag ccgcaccggt acaggcgcaa ccgcgccagt ctaaaccggc
     5281 ttcttctcag cagccgtacc aggatctgct gcaaactcct gcgcacacga ctgcgcagtc
     5341 gaagccgcag caagctgcgc cagttgctcg tgccgctgac gcgccaaaac cgacggcgga
     5401 gaaaaaagac gaacgccgct ggatggtgca gtgcggttcg ttcagaggcg cggaacaggc
     5461 agagacggta cgtgctcagc tggcgttcga aggctttgac tcgaaaatca ccaccaacaa
     5521 tggctggaat cgtgtggtca ttggcccggt gaaaggcaaa gagaacgcag acagcaccct
     5581 caatcggttg aagatggcgg gtcatacaaa ctgcattcgg ctcgccgccg ggggttgaaa
     5641 ccctcaaaat cccccccatc tataattgca ttatgccccg tacttttgta cggggtttgt
     5701 actctgtatt cgtaaccaag gggtcagctc gtgacaacta tagtaagcgt acgccgtaac
     5761 ggccatgtgg tcatcgctgg tgatggtcag gccacgttgg gcaataccgt aatgaaaggc
     5821 aacgtgaaaa aggtccgccg tctgtacaac gacaaagtca tcgcgggctt tgcgggcggt
     5881 actgcggatg cttttacgct gttcgaactg tttgaacgta aactggaaat gcatcagggc
     5941 catctggtca aagccgccgt tgagctggca aaagactggc gtaccgatcg catgctgcgc
     6001 aaacttgaag cactgctggc agtcgcggat gaaactgcat cgcttatcat caccggtaac
     6061 ggtgacgtgg tgcagccaga aaacgatctt attgctatcg gctccggcgg cccttacgcc
     6121 caggctgcgg cgcgcgcgct gttagaaaac actgaactta gcgcccgtga aattgctgaa
     6181 aaggcgttgg atattgcagg cgacatttgc atctatacca accatttcca caccatcgaa
     6241 gaattaagct acaaagcgta aggatctccc atgtctgaaa tgaccccacg cgaaatcgtc
     6301 agcgaactgg ataagcacat catcggccag gacaacgcca agcgttctgt ggcgattgct
     6361 ctgcgtaacc gctggcgtcg catgcagctc aacgaagagc tgcgccatga agtgaccccg
     6421 aaaaatatcc tgatgatcgg cccgaccggt gtcggtaaaa ctgaaatcgc ccgtcgtctg
     6481 gctaagctgg cgaatgcgcc gttcatcaaa gttgaagcga ccaaattcac cgaagtgggc
     6541 tacgtcggta aggaagtgga ttctattatt cgcgatctga ccgatgccgc cgtgaaaatg
     6601 gtacgcgtcc aggctatcga gaaaaaccgt tatcgcgctg aagaactggc agaagaacgt
     6661 attctcgacg tgctgatccc acctgctaaa aacaactggg gacagaccga acagcagcag
     6721 gaaccgtccg ctgctcgtca ggcattccgc aaaaaactgc gtgaaggcca gcttgatgac
     6781 aaagaaatcg agatcgatct tgccgcagca ccgatgggcg ttgaaattat ggctcctccg
     6841 ggcatggaag agatgaccag ccagctgcag tccatgttcc agaacctggg cggccagaag
     6901 caaaaagcgc gtaagctgaa aatcaaagac gccatgaagc tgctgattga agaagaagcg
     6961 gcgaaactgg tgaacccgga agagctgaag caagacgcta tcgacgctgt tgagcagcac
     7021 gggatcgtgt ttatcgacga aatcgacaaa atctgtaagc gcggcgagtc ttccggtccg
     7081 gatgtttctc gtgaaggcgt tcagcgtgac ctgctgccgc tggtagaagg ttgcaccgtt
     7141 tccaccaaac acgggatggt caaaactgac cacattctgt ttatcgcttc tggcgcgttc
     7201 cagattgcga aaccgtctga cctgatcccg gaactgcaag gtcgtctgcc aatccgcgtt
     7261 gaactgcagg cgctgaccac cagcgacttc gagcgtattc tgaccgagcc gaatgcctct
     7321 atcaccgtgc agtacaaagc actgatggcg actgaaggcg taaatatcga gtttaccgac
     7381 tccggtatta aacgcatcgc ggaagcggca tggcaggtga acgaatctac cgaaaacatc
     7441 ggtgctcgtc gtttacacac tgttctggag cgtttaatgg aagagatttc ctacgacgcc
     7501 agcgatttaa gcggtcaaaa tatcactatt gacgcagatt atgtgagcaa acatctggat
     7561 gcgttggtgg cagatgaaga tctgagccgt tttatcctat aatcgcgttc aatcattttc
     7621 atcattgttt gatggggctg aaaggcccca tttttattgg cgcgtattat gactgaacaa
     7681 caaattagcc gaactcaggc gtggctggaa agtttacgac ctaaaaccct ccccctcgcc
     7741 tttgctgcaa ttatcgtcgg gacagcgctg gcatggtggc aaggtcactt cgatccgctg
     7801 gtcgccctgc tggcactaat taccgccggg ctattacaga tcctttctaa cctcgccaat
     7861 gattacggcg atgcggtaaa aggcagcgat aaacctgacc gcattgggcc gctacgcggc
     7921 atgcaaaaag gggtcattac ccagcaagag atgaaacggg cgctcattat taccgtcgtg
     7981 ctcatctgtc tctccgggct ggcactggtt gcagtggcat gccatacgct ggccgatttt
     8041 gtcggtttcc tgattcttgg cgggttgtcg atcattgccg ctatcaccta caccgtgggc
     8101 aatcgtcctt atggttatat cggtctgggt gatatttccg tactggtttt ctttggctgg
     8161 ttgagtgtca tggggagctg gtatttacag gctcatacat tgattccggc actgatcctt
     8221 ccggcgaccg catgcggcct gctggcaacg gcagtactga atattaataa cctgcgtgat
     8281 atcaatagcg accgcgaaaa tggcaaaaac acgctggtgg tgcgcttagg tgaagtgaac
     8341 gcgcgtcgtt atcatgcctg cctgctgatg ggctcgctgg tgtgtctggc gctgtttaat
     8401 ctcttttcgc tgcatagcct gtggggctgg ctgttcctgc tggcggcacc attactggtg
     8461 aagcaagccc gttatgtgat gcgggaaatg gacccggtgg cgatgcgacc aatgctggaa
     8521 cgtactgtca agggagcgtt actgactaac ctgctgtttg ttttagggat attcctaagc
     8581 cagtgggcag cataactgac aaatatcaat taacaattga tgattttgcc aacagcccac
     8641 atagcgcgat atactgaaaa ttctcgcagc aactgaatgt taagcctatg aaatacgata
     8701 cttccgagct ttgtgacatc tatcaagaag atgttaacgt cgtggaaccg ctgttctcca
     8761 actttggcgg acgggcgtcg tttggcggac aaataatcac ggtaaaatgt ttcgaggaca
     8821 acgggttgct gtacgatctg ctcgaacaga atggccgtgg tcgtgttctt gtcgtcgatg
     8881 gcggtggttc tgttcgtcgc gcactggtcg atgctgaact ggcgcgtctg gcagtacaaa
     8941 atgaatggga aggtctggtc atttacggcg cggtgcgtca ggtagatgac ctggaagagt
     9001 tggatatcgg catccaggcg atggcggcaa ttccggttgg tgccgctggc gaaggcattg
     9061 gcgaaagcga tgtccgcgtc aattttggcg gtgtcacctt cttctccggc gaccatcttt
     9121 atgccgacaa taccgggatt attctttcag aagatccgct ggatattgaa tgataagaaa
     9181 ggcaccgcaa ggtgcctttt ttctgcgtta cctgttggcc tacacagtaa agaaattacg
     9241 cggaagatga agcgtaatca gacctcttcc atgcgaccca gcagggcctg cagacgttcc
     9301 tgccagccgt tctgctgttc tttcagatgg ttgttctcac gctccagctc ttcgcgctga
     9361 tgctgggcat tttgaacttc ctgcgacagt gagttgtttt tttctttcag ctcttcgatt
     9421 tccatctgca acagagtgat ggtatcaatc gcctgctgta cttttgcttc cagtttctca
     9481 aacacttcta atgacattgt catacctctc ctgaattgca aggcgttgat ggataaaaat
     9541 cctcgtcccg attaccggtg acgccttaat aaatacgagc gcactttagt tagctccgat
     9601 tgtatgaagc cgcgccatcg ctgtccagcg gcacgccttg cagattacgg tttgccacac
     9661 ttttcatcct tctcctggtg acataatcca catcaatcga aaatgttaat aaatttgttg
     9721 cgcgaatgat ctaacaaaca tgcatcatgt acaatcagat ggaataaatg gcgcgataac
     9781 gctcatttta tgacgaggca cacacatttt aagttcgata tttctcgttt ttgctcgtta
     9841 acgataagtt tacagcatgc ctacaagcat cgtggaggtc cgtgactttc acgcatacaa
     9901 caaacattaa ctcttcagga tccgattatg agtcaaacat caaccttgaa aggccagtgc
     9961 attgctgaat tcctcggtac cgggttgttg attttcttcg gtgtgggttg cgttgcagca
    10021 ctaaaagtcg ctggtgcgtc ttttggtcag tgggaaatca gtgtcatttg gggactgggg
    10081 gtggcaatgg ccatctacct gaccgcaggg gtttccggcg cgcatcttaa tcccgctgtt
    10141 accattgcat tgtggctgtt tgcctgtttc gacaagcgca aagttattcc ttttatcgtt
    10201 tcacaagttg ccggcgcttt ctgtgctgcg gctttagttt acgggcttta ctacaattta
    10261 tttttcgact tcgagcagac tcatcacatt gttcgcggca gcgttgaaag tgttgatctg
    10321 gctggcactt tctctactta ccctaatcct catatcaatt ttgtgcaggc tttcgcagtt
    10381 gagatggtga ttaccgctat tctgatgggg ctgatcctgg cgttaacgga cgatggcaac
    10441 ggtgtaccac gcggcccttt ggctcccttg ctgattggtc tactgattgc ggtcattggc
    10501 gcatctatgg gcccattgac aggttttgcc atgaacccag cgcgtgactt cggtccgaaa
    10561 gtctttgcct ggctggcggg ctggggcaat gtcgccttta ccggcggcag agacattcct
    10621 tacttcctgg tgccgctttt cggccctatc gttggcgcga ttgtaggtgc atttgcctac
    10681 cgcaaactga ttggtcgcca tttgccttgc gatatctgtg ttgtggaaga aaaggaaacc
    10741 acaactcctt cagaacaaaa agcttcgctg taatatgact acgggacaat taaacatgac
    10801 tgaaaaaaaa tatatcgttg cgctcgacca gggcaccacc agctcccgcg cggtcgtaat
    10861 ggatcacgat gccaatatca ttagcgtgtc gcagcgcgaa tttgagcaaa tctacccaaa
    10921 accaggttgg gtagaacacg acccaatgga aatctgggcc acccaaagct ccacgctggt
    10981 agaagtgctg gcgaaagccg atatcagttc cgatcaaatt gcagctatcg gtattacgaa
    11041 ccagcgtgaa accactattg tctgggaaaa agaaaccggc aagcctatct ataacgccat
    11101 tgtctggcag tgccgtcgta ccgcagaaat ctgcgagcat ttaaaacgtg acggtttaga
    11161 agattatatc cgcagcaata ccggtctggt gattgacccg tacttttctg gcaccaaagt
    11221 gaagtggatc ctcgaccatg tggaaggctc tcgcgagcgt gcacgtcgtg gtgaattgct
    11281 gtttggtacg gttgatacgt ggcttatctg gaaaatgact cagggccgtg tccatgtgac
    11341 cgattacacc aacgcctctc gtaccatgtt gttcaacatc cataccctgg actgggacga
    11401 caaaatgctg gaagtgctgg atattccgcg cgagatgctg ccagaagtgc gtcgttcttc
    11461 cgaagtatac ggtcagacta acattggcgg caaaggcggc acgcgtattc caatctccgg
    11521 gatcgccggt gaccagcagg ccgcgctgtt tggtcagttg tgcgtgaaag aagggatggc
    11581 gaagaacacc tatggcactg gctgctttat gctgatgaac actggcgaga aagcggtgaa
    11641 atcagaaaac ggcctgctga ccaccatcgc ctgcggcccg actggcgaag tgaactatgc
    11701 gttggaaggt gcggtgttta tggcaggcgc atccattcag tggctgcgcg atgaaatgaa
    11761 gttgattaac gacgcctacg attccgaata tttcgccacc aaagtgcaaa acaccaatgg
    11821 tgtgtatgtg gttccggcat ttaccgggct gggtgcgccg tactgggacc cgtatgcgcg
    11881 cggggcgatt ttcggtctga ctcgtggggt gaacgctaac cacattatac gcgcgacgct
    11941 ggagtctatt gcttatcaga cgcgtgacgt gctggaagcg atgcaggccg actctggtat
    12001 ccgtctgcac gccctgcgcg tggatggtgg cgcagtagca aacaatttcc tgatgcagtt
    12061 ccagtccgat attctcggca cccgcgttga gcgcccggaa gtgcgcgaag tcaccgcatt
    12121 gggtgcggcc tatctcgcag gcctggcggt tggcttctgg cagaacctcg acgagctgca
    12181 agagaaagcg gtgattgagc gcgagttccg tccaggcatc gaaaccactg agcgtaatta
    12241 ccgttacgca ggctggaaaa aagcggttaa acgcgcgatg gcgtgggaag aacacgacga
    12301 ataatgtaaa tgccgaatga agcgtttatg ccgcatccgg tagtcccgaa acgtgcgggg
    12361 gcaaccccgc acacatcaat aatccctccc ttcccctgtg ctacacttcg cgccattcct
    12421 tactgcttag agtttgctat gagacgagaa cttgccatcg aattttcccg cgtcaccgaa
    12481 tcagcggcgc tggctggcta caaatggtta ggacgcggcg ataaaaacac cgcggacggc
    12541 gcggcggtaa acgccatgcg tattatgctc aaccaggtca acattgacgg caccatcgtt
    12601 attggtgaag gtgaaatcga cgaagcaccg atgctctaca ttggtgaaaa agtcggtact
    12661 ggtcgcggcg acgcggtaga tattgctgtt gatccgattg aaggcacgcg catgacggcg
    12721 atgggccagg ctaacgcgct ggcggtgctg gcagtaggcg ataaaggctg cttcctcaat
    12781 gcgccggata tgtatatgga gaagctgatt gtcgggccgg gagccaaagg caccattgat
    12841 ctgaacctgc cgctggcgga taacctgcgc aatgtagcgg cggcgctcgg caaaccgttg
    12901 agcgaactga cggtaacgat tctggctaaa ccacgccacg atgccgttat cgctgaaatg
    12961 cagcaactcg gcgtacgcgt atttgctatt ccggacggcg acgttgcggc ctcaattctc
    13021 acctgtatgc cagacagcga agttgacgtg ctgtacggta ttggtggcgc gccggaaggc
    13081 gtagtttctg cggcggtgat ccgcgcatta gatggcgaca tgaacggtcg tctgctggcg
    13141 cgtcatgacg tcaaaggcga caacgaagag aatcgtcgca ttggcgagca ggagctggca
    13201 cgctgcaaag cgatgggcat cgaagccggt aaagtattgc gcctgggcga tatggcgcgc
    13261 agcgataacg tcatcttctc tgccaccggt attaccaaag gcgatctgct ggaaggcatt
    13321 agccgcaaag gcaatatcgc gactaccgaa acgctgctga tccgcggcaa gtcacgcacc
    13381 attcgccgca ttcagtccat ccactatctg gatcgcaaag acccggaaat gcaggtgcac
    13441 atcctctgat tgatttgatc gattgagcct tccagtcctt cgggactgga atttttttgt
    13501 tcggagaacg aagataaggc aagtcaatca aaacaggaga aaaacatggc tgattgggta
    13561 acaggcaaag tcactaaagt gcagaactgg accgacgccc tgtttagtct caccgttcac
    13621 gcccccgtgc ttccgtttac cgccgggcaa tttaccaagc ttggccttga aatcgacggc
    13681 gaacgcgtcc agcgcgccta ctcctatgta aactcgcccg ataatcccga tctggagttt
    13741 tacctggtca ccgtccccga tggcaaatta agcccacgac tggcggcact gaaaccaggc
    13801 gatgaagtgc aggtggttag cgaagcggca ggattctttg tgctcgatga agtgccgcac
    13861 tgcgaaacgc tatggatgct ggcaaccggt acagcgattg gcccttattt atcgattctg
    13921 caactaggta aagatttaga tcgcttcaaa aatctggtcc tggtgcacgc cgcacgttat
    13981 gccgccgact taagctattt gccactgatg caggaactgg aaaaacgcta cgaaggaaaa
    14041 ctgcgcattc agacggtggt cagtcgggaa acggcagcgg ggtcgctcac cggacggata
    14101 ccggcattaa ttgaaagtgg ggaactggaa agcacgattg gcctgccgat gaataaagaa
    14161 accagccatg tgatgctgtg cggcaatcca cagatggtgc gcgatacaca acagttgctg
    14221 aaagagaccc ggcagatgac gaaacattta cgtcgccgac cgggccatat gacagcggag
    14281 cattactggt aagcggttac ttatcgataa acggcacgat gagcaaatcc gcactcatct
    14341 tattgatcat cccgcgatat gccggcatca aacggttgat aaatgagtga tgatgaccac
    14401 agacaaggag gtcgcactgc tctttttgca taatttccag cagtgtttcc ggcatttctc
    14461 cgcgttcaat acgcagtttt gtcttcggcc attgaatatt tttcgtcagt ttatatagct
    14521 tgttatccga cttattcttc aacaattgaa gaatatcttc tgttgcaggg aagtagatac
    14581 ccggatacaa ctcgcttaag ccatcatcaa tatgaattaa cgtcaggtga gcgtcattat
    14641 gtctggcgag ctccagggct ttattcacca gtaaggcatc ttcttcattc ccggaaattg
    14701 ccacgccaat gtgtttataa gccatgttta actccttcta aagcaactcc atcaagctaa
    14761 cgaacgcagt gataactcaa aaataatcat ctcggcctgg catgagaaag tgaaggccgc
    14821 atcaagctca acttgcccct ccagatcctt aatcttatag gccacgctgg ccccttcatc
    14881 tgcagaggat gtagcggcgg caagctcttt cagtttggtc ataaaagact ctgcttcttc
    14941 gcgggtggca aaaaagcgcg aaaacttact ggtacagttg tcgttatcaa tcaccgtacc
    15001 gatatcaatc gcacatcctt tagtactgca tttatctacg acatctttca tagggcacct
    15061 ctgtatattc gcctctctgt cgattacgac ttaagaataa tgcgccgtta agggaagaac
    15121 aaacaagtaa tgatcttatg gattaccatt ttttttgata ttgcttaagg tgaagagttc
    15181 agaaggattt tccgggtatt gtcatttgca tcgtggaaat aacaatcccg gaaaaaaata
    15241 gcagtaagag atatattaaa ggttaattac ttgatttatt gtcggcttta tacttcacat
    15301 cctgagtatc tttaccatat ttattttcgc cttgtgtgcc aacaaacgca ccaagatcga
    15361 taagcatcat caccagaatc aacgtcggga caaaacgccc caccgcccat tgccagacac
    15421 ccggtaaaat cgcccagtta cccgccagca gcatccacgc cacaatcatc agaaatgccc
    15481 atgcgccgga acgcccgcga tcatgcaagc gcttaacagt tactgccgct gttggccaga
    15541 gcaagcacac aaggcaaaac gccgcggtct gaatatcgag tagattctta cccgccagtg
    15601 agaaaagcac cagcatgcct gcgaaccaca ggcctatcca aatccagaaa tcacggcgtc
    15661 caatacgccc tttaaatgag aataaccatt gctgtatggt catgtaagtt ccttgatggt
    15721 tgtcttttcc aggattctac ccttttgaca agggcgacag atatcgtttt aatcggagcc
    15781 agtcataaca aaaggtactg tcaatgaagc cagggtgtac gctgtttttt ctcttatgtt
    15841 ctgcattaac cgttacaaca gcggcgcatg cacaaacacc agatacggca acgaccgcgc
    15901 cttatctgct ggctggagcc cctactttcg atctctccat cagccagttt cgagaagact
    15961 ttaacagcca gaatcccagc ctgccactga acgaatttcg tgccatcgac agcagtcccg
    16021 acaaagccaa tctcactcgt gctgcaagta aaattaatga gaacttgtat gcttctacag
    16081 cgctggagcg cggtacctta aaaatcaaaa gcattcaaat gacctggcta cccatccagg
    16141 ggccagagca aaaagccgcg aaagcgaaag ctcaggaata catggcagcg gtgatccgca
    16201 cactcacccc attaatgacc aaaacacaaa gccagaaaaa actgcagtcg ctactaacgg
    16261 cggggaaaaa caaacgttat tacaccgaga cagaaggtgc actgcgttat gttgtcgcgg
    16321 acaacggcga aaaggggctg accttcgctg ttgaaccgat taagctggcg ctatctgaat
    16381 cgcttgaagg tttgaataaa tgacaaaaag caaagccttt gtgccgatga atctctatac
    16441 tgtttcacag acctgctgcc ctgcggggcg gccatcttcc tttattcgct tataagcgtg
    16501 gagaattaaa atgcgacatc ctttagtgat gggtaactgg aaactgaacg gcagccgcca
    16561 catggttcac gagctggttt ctaacctgcg taaagagctg gcaggtgttg ctggctgtgc
    16621 ggttgcaatc gcaccaccgg aaatgtatat cgatatggcg aagcgcgaag ctgaaggcag
    16681 ccacatcatg ctgggtgcgc aaaacgtgga cctgaacctg tccggcgcat tcaccggtga
    16741 aacctctgct gctatgctga aagacatcgg cgcacagtac atcatcatcg gtcactctga
    16801 acgtcgtact taccacaaag aatctgacga actgatcgcg aaaaaattcg cggtgctgaa
    16861 agagcagggc ctgactccgg ttctgtgcat cggtgaaacc gaagctgaaa atgaagcggg
    16921 caaaactgaa gaagtttgcg cacgtcagat cgacgcggta ctgaaaactc agggtgctgc
    16981 ggcattcgaa ggtgcggtta tcgcttacga acctgtatgg gcaatcggta ctggcaaatc
    17041 tgcaactccg gctcaggcac aggctgttca caaattcatc cgtgaccaca tcgctaaagt
    17101 tgacgctaac atcgctgaac aagtgatcat tcagtacggc ggctctgtaa acgcgtctaa
    17161 cgctgcagaa ctgtttgctc agccggatat cgacggcgcg ctggttggtg gtgcttctct
    17221 gaaagctgaa gccttcgcag taatcgttaa agctgcagaa gcggctaaac aggcttaagt
    17281 ctgacaggtg ccggatttca tatccggcac ttactttcct taactcttcg ccttaacgca
    17341 aaatctcaca ctgatgatcc tgaatttcct cggctgaagc acggttaagc gtcagtagat
    17401 ttcgttgtgt cgccagcaat acaaatgagt tatcactctg ccgtaccatc gccagcccgt
    17461 agcgtcccat atgttcccgc gcctcaggta cttcttctgc cagcatcata aatgggctgc
    17521 gttgtaccag ttcgctttcc gttacccgac gcgccaggta ttcatgcccg cgcaaaccac
    17581 ctggcagtgg caaccagcgg ctgctgatgt tcgccagatt gttatccagc tgtttgcgca
    17641 catcaggacg aatacaagag atatgaatat gaaaatggtt ttgcgtacgc ccggtgcggg
    17701 agttgatcgc caaagaaacc gcgcgatcgg gaaccggctg gccgtatttt ttgctcataa
    17761 aatcacgcgc ctgccaagcc aaccaaaaga agttcggcgt tgaaggatcg gtcaacaaag
    17821 gactttcagt accgttaata cgatacgttg gcatcaacag atattgcagt gggccattaa
    17881 gatcttttaa aaccacgtat ccggcattgg gtttgacttc cgcacatggc gaaggatttt
    17941 gattttgctg ctgattgggc aaacattcct caaggacaat cttacgtaat gtatccgact
    18001 cttcaccggt taatttccag taaccaatac cggcagccac aacggcgata actatcatca
    18061 ccaaaaaaag aagacccgct tttttcatct ttttttccct gtacctcaaa gagatgcaag
    18121 ggtaacgcaa aatcgtgaca aataaaaaac ccggtcgcga gaaaccaccg ggtttgataa
    18181 ttatcctggg gaaatcagcg tttgctgatc tgatcgaacg taccgccgtt agcaaaatgc
    18241 tctttttgcg ctttcgtcca gccgccgaac tcttcatcaa tggtgaataa cttcagcttt
    18301 ggaaacgcat tttcgtactt tttcgccacc tcagcgtcgc gcggacggta gtagtttttc
    18361 gcggcaattt cctgaccttc tggcgagtag agatatttca ggtaggcttc cgccacctct
    18421 ttagtacctt ttttctcgac cactttatcg accaccgaca cggttggctc tgcgaggata
    18481 gactcactcg gcgtgacgat ttcgaattta tctttcccca gttcattcgc tgccagcaga
    18541 gcttcgtttt cccaggcaat cagtacatcg ccaattccgc gctcgacaaa agtgttagtg
    18601 gagccacgcg cgccagaatc cagaacttcg acgtttttat acagtgcccg aataaaatcc
    18661 tgtgcttttg cctgatcgtt gttgttgtga tgcagcgcgt agccccaggc tgccaggtag
    18721 ttccagcgcg cgccaccaga gcttttcgga ttaggcgtga tcaccgaaac acccggttta
    18781 atcagatcgt tccagtcatg gatctgcttc ggatttccct tacgtaccag gaaaacaatg
    18841 gtggaagtgt acggtgcgga gttatccggc agacgtttga tccactcttt atcaatccgc
    18901 ccgcgttccg caattgcgtc cacgtcatag gccagagcca gcgtgacaac atcagcttca
    18961 ataccgttga ttaccgacgt cgcttgttta cctgagccac cgtgtgactg acgaatcacc
    19021 acgttatcac cagtttgctg tttccagtgg gcgctgaatg ccttgttgta ctgttcgtac
    19081 aattcgcgcg ttggatcata tgaaacgtta agaagctgaa tatcctttgc cataacgctg
    19141 gttgccgcca gcaaaaatgt taaccctacg ccccacttgt tcatcgcccg actctcttat
    19201 gttgtgttgt gatgagcaaa gcgtgccaga aggttaacca aacattaaag aataaaaaaa
    19261 gattggctat aacttgcggg tatatgttga gggattaaaa aggcggaaga aatccgcctc
    19321 atattgctga caaagtgcgc tttgtccatg ccggatgcgg cgcgaacgcc ttatccggcc
    19381 tacaaaagtt tgcaaattca ataaattgca gaattcatgt aggcctgata agcgaagcgc
    19441 atcaggcatt tttgcttctg tcatcggttt cagggtaaag gaatctgcct ttttccgaaa
    19501 tcattaatac agttttttcg cgcagtccag ccagtcacct ttgaacggac gcttcatgtt
    19561 ttcgatagcg tcgatgatgt cgtggtgaac cagctgttcg ttctggatac ctacacaacg
    19621 accgccgtaa cctgccagca gcagatcgat agcgtaagcg cccatacggg aagccagaat
    19681 acggtcgtaa ggcaccggag aaccaccgcg ctggatgtgg cccagcacag ttgcgcgggt
    19741 ttcacgaccg gtttctttct cgatgaaatg cgccagttcg tcaacatcac acatatgttc
    19801 ggtaatcgcc acgatcgcgt gttttttacc tttcgcgata cccgctttga tttcgtttac
    19861 caggtcttca cggctgaatt caacttccgg aaccacaacg aattcacagc caccggcaat
    19921 ggccgcagcc aacgtcagat ctccacaata acggcccatc acttccacca cggaaatacg
    19981 ctggtgagaa gaagaggtgt cacgcagacg gtcgatcgct tctacaacgg tgctcagcgc
    20041 agtgaagaaa ccgatagtgt agtcagtgcc tttgatgtcg ttgtcgatag tgcccggcag
    20101 accgatgcac gggaagccca tttcggtcag acgcattgca cccatgtagg aaccgtcacc
    20161 gccgataacc accagcgcgt cgataccacg ttttttcagg ttttcgatag ccacggcgcg
    20221 gatgttctcg tcgcggaatt ccgggaaacg cgcagaaccg aggaacgtac cgccacggtt
    20281 gatcatgtca gacacgctgt aacggtctag ctgtaccata cggtcttcat acagacccag
    20341 atagccgtca taaataccca ttacttccag accttctgtc agcgcagaac gaacaacccc
    20401 gcgaattgcg gcgttcatgc ctggcgcatc accgccgctt gtcaacacac cgattttctt
    20461 aatcatgact acctctgaac tttggaatgc aaaatgaaat ctgttgccgg aagtcttctt
    20521 gcacatcgaa gtgatccaac gaatgtgcaa atagtataac aatcacttcc tgctgaattg
    20581 attcaggtca ggccaaatgg cggtatttta tacacaaaat gcgggtctgg ctctctttta
    20641 tactgattat gaaagcatag accgtttacc ctccctgggt acgacggaac aggggtcctg
    20701 atggataatt acatccgatc ccggaaaacg ccgtaaaata gcctgctcta cctgatccgc
    20761 caccatatgt gcctgaacca aaggcagaga gtcttccatt tccaaatgaa tctgaataaa
    20821 gcgggtcggc cctgactgcc gcgtgcgaag atcgtgagcg ccgctaacac ccggccagga
    20881 agtcacgata tcaataattt cttgccgttc ctcatcaggc aatgcgcgat ccagtaatga
    20941 ctgtaccgcc tcatatccca tgcgtaacgc gctatataaa atatagatgc cgattcccaa
    21001 tgcaaacaga gcatcggcgc gatgccagcc gtaccaggac aaccccagcg ccagcagaat
    21061 tgcgccgttc atcataacat cagactggta atgtagcata tcagcccgca cagcctggct
    21121 ttgcgtccgc cgcaccaccc aacgctgaaa cgagacaagg ataatcgtac aaattagcgc
    21181 cacaattgtc acgataaccc cgacgcctgg atctgtcatc ggtgttggag atatcagatg
    21241 ttgaataccc gtcaaaaaca ggaatagtgc cgaaccggag ataaacatac tttgcgccag
    21301 cgccgcgagg gactcagctt taccgtgacc aaacgagtga ttatcgtcgg caggttgcag
    21361 ggaatatcgc accaccaata aattcgtcaa cgacgcaccg atatccacca gcgaatccac
    21421 cagcgcggcg agaatactca ccgacccggt ataccaccat gcaaaaattt taatcagcaa
    21481 tagcagcgaa gccatcgccg tcgcagcaat cgccgcccga ctgaccagcc gtccataaga
    21541 ttgattcata aatactcccg ctatcaactg acgctagtat aacggaagca aatcatctgc
    21601 aatgcattaa gcagcaggca aattgaggat aaaaaaaacc ccccacagca tgtgggggaa
    21661 gacagggatg gtgtctatgg caaggaaaac agggtttact actgggaacg tgagttgcta
    21721 ctactcaata gcttcaacga tgaacttttt tgccattgcg tcacgtcacg caactgctcc
    21781 attcgttgtt gatgtttctc gtttaaaacc gcttgctgct ccggcgttaa caggcgatac
    21841 atttggttgc ggacttttgc catctcaacc tgacgagcaa tttgctcatt cgccattttt
    21901 tctgcctgtg cgcgcacagc gttttcatca aaattttctg cggtgacaag gcgatgcatt
    21961 gtctccagtt cgctaacatt aacaggaggc tgttcgtgcc gggcctgttg cataagatct
    22021 cgcatctgct gacgctgatg ttcggttaaa cttatgccgt cgaacatatg gctctgcgta
    22081 ctgcgctgcg taagttcttc acccggatgc cagttatcgc ctgaaccgac ttcagcagcg
    22141 tggcttaatg aactgactgc cagcgttgag gccatgacgg cagcggtaac tatgcgcatc
    22201 atttgctccc aaaatctttc tgtcgcgatt caacgataga gagtttacga ttcaggctgc
    22261 aaacatgcgt cagggggtgt aaaacaacgt aaagtcatgg attagcgacg tctgatgacg
    22321 taatttctgc ctcggaggta tttaaacaat gaataaaatc ctgttagttg atgatgaccg
    22381 agagctgact tccctattaa aggagctgct cgagatggaa ggcttcaacg tgattgttgc
    22441 ccacgatggg gaacaggcgc ttgatcttct ggacgacagc attgatttac ttttgcttga
    22501 cgtaatgatg ccgaagaaaa atggtatcga cacattaaaa gcacttcgcc agacacacca
    22561 gacgcctgtc attatgttga cggcgcgcgg cagtgaactt gatcgcgttc tcggccttga
    22621 gctgggcgca gatgactatc tcccgaaacc gtttaatgat cgtgagctgg tggcacgtat
    22681 tcgcgcgatc ctgcgccgtt cgcactggag cgagcaacag caaaacaacg acaacggttc
    22741 accgacactg gaagttgatg ccttagtgct gaatccaggc cgtcaggaag ccagcttcga
    22801 cgggcaaacg ctggagttaa ccggtactga gtttaccctg ctctatttgc tggcacagca
    22861 tctgggtcag gtggtttccc gtgaacattt aagccaggaa gtgttgggca aacgcctgac
    22921 gcctttcgac cgcgctattg atatgcacat ttccaacctg cgtcgtaaac tgccggatcg
    22981 taaagatggt cacccgtggt ttaaaacctt gcgtggtcgc ggctatctga tggtttctgc
    23041 ttcatgatag gcagcttaac cgcgcgcatc ttcgccatct tctggctgac gctggcgctg
    23101 gtgttgatgt tggttttgat gttacccaag ctcgattcac gccagatgac cgagcttctg
    23161 gatagcgaac agcgtcaggg gctgatgatt gagcagcatg tcgaagcgga gctggcgaac
    23221 gatccgccca acgatttaat gtggtggcgg cgtctgttcc gggcgattga taagtgggca
    23281 ccgccaggac agcgtttgtt attggtgacc accgaaggcc gcgtgatcgg cgctgaacgc
    23341 agcgaaatgc agatcattcg taactttatt ggtcaggccg ataacgccga tcatccgcag
    23401 aagaaaaagt atggccgcgt ggaactggtc ggtccgttct ccgtgcgtga tggcgaagat
    23461 aattaccaac tttatctgat tcgtccggcc agcagttctc aatccgattt cattaactta
    23521 ctgtttgacc gcccgctatt actgctgatt gtcaccatgt tggtcagtac gccgctgctg
    23581 ttgtggttgg cctggagtct ggcaaaaccg gcgcgtaagc tgaaaaacgc tgccgatgaa
    23641 gttgcccagg gaaacttacg ccagcacccg gaactggaag cggggccaca ggaattcctt
    23701 gccgcaggtg ccagttttaa ccagatggtc accgcgctgg agcgcatgat gacctctcag
    23761 cagcgtctgc tttctgatat ctctcacgag ctgcgcaccc cgctgacgcg tctgcaactg
    23821 ggtacggcgt tactgcgccg tcgtagcggt gaaagcaagg aactggagcg tattgaaacc
    23881 gaagcgcaac gtctggacag catgatcaac gatctgttgg tgatgtcacg taatcagcaa
    23941 aaaaacgcgc tggttagcga aaccatcaaa gccaaccagt tgtggagtga agtgctggat
    24001 aacgcggcgt tcgaagccga gcaaatgggc aagtcgttga cagttaactt cccgcctggg
    24061 ccgtggccgc tgtacggcaa tccgaacgcc ctggaaagtg cgctggaaaa cattgttcgt
    24121 aatgctctgc gttattccca tacgaagatt gaagtgggct ttgcggtaga taaagacggt
    24181 atcaccatta cggtggacga cgatggtcct ggcgttagcc cggaagatcg cgaacagatt
    24241 ttccgtccgt tctatcgtac cgatgaagca cgcgatcgtg aatctggcgg tacaggtttg
    24301 gggctggcga ttgttgaaac cgccattcag cagcatcgtg gctgggtgaa ggcagaagac
    24361 agcccgctgg gcggtttacg gctggtgatt tggttgccgc tgtataagcg gagttaaact
    24421 tcgcatttgc aggcaggata aggcgtttac gccgcatccg gcatttgagc aggatgcctg
    24481 atgcgacgct gatagcgtct tatcaggcct acactccggg ggttattttc cccacaaccg
    24541 gcgggaaaaa tcttcgatct tgccgctcag tcggcgcttt tgcatcgtcc gcgtccagct
    24601 tttcgataac ccggcagcgg agagtaaacg gtgatattga tcgtcatcaa acggcatatg
    24661 ccatgcgatg gcggcagcct cctgcacggt cacatcgctg acacgggaaa ccaactccag
    24721 cggcgcgtcc gcagacactt tccctggcgc tatcacgcta tacaaccacc ccaccttacc
    24781 tgtgttttgc atcaactgcg ctatatcgct gatatcaaaa tggtaattga gtttatagca
    24841 aggcgagcgc ggctggctga cctgaattaa tgcctctccc cagcggaaaa tatcgcccat
    24901 ataaacatta ctttccgtca ggccgtcggt tgagaggttt tcaccaaacg caggcgcaac
    24961 aaacaactcc gcctgttccg gaaattcccg cgcccagtag agataatgct cacgaggata
    25021 atgacacagc gctctgtctg gcccgccgtg aacctttttc tccgcctgct cgtcaccttc
    25081 cagccccagc tccgtcagca tcaactcacc atcaacctgg attttagcaa ttgcgctggg
    25141 tttgccttcg ggataagcct gaatcttgcc tgtgtataca tcaaccggat atcgcatctg
    25201 ttccctctcc acgagaaatt tccccattag accatattta ttttatgtca ggcgtgctgt
    25261 tttcgcggta agtatccagg caggaactca atagcaaacc ggacgaacgt tagttcatcc
    25321 ggctgtgggg attaaggaag caggtttatt tcaccgtacc taaaatttcg attttcgctg
    25381 ctctggcttt gactttacgt gaccagatag aggtaagaat tggcaccaga atcgaagtca
    25441 caatgaccgc cgtcgctacc agcgaagttg ctgccggagc catcggttta aacgcaggca
    25501 ccatttctgc aatcagcaca ggtgtcgcta ccgcggcccc tgcggaactg gaagcggcaa
    25561 ttccggcagt gccatcgcca ccgccaatca atttatcggc gataatcaac ggaataccgg
    25621 tcacgataat tactgccaca cccaacagga tccccagcaa accagtctgg gcaatcacag
    25681 tcaaatcaat ggtattgccc agcgcgaagg caaagaatgg aatcagcgtt tgcaccgctt
    25741 tgctgaaaaa ttctcgcaat tcagggtcaa ggttccccag ggcaaagccc accaggaacg
    25801 gtaatactgc gccgacgaaa acatgcggtt caaacgaggc aatcccggca gtgcccagaa
    25861 taatcatcgt catgagcggc ccggactcca acgacatcaa cacaaatgcc ccagcttctt
    25921 cttttgtgcc gtactgctgc atgatggaag cgtaaagtcc gccattggtc atatccatcg
    25981 ccgccaccag cgccagcgtt gaaagtccgg caaagaatcc aacttcaaca ccatgttccg
    26041 gaataatacg cgaggcaatt gccgcaacca cccacgcgac ggcaatttta gttaccacca
    26101 gcgtaccgga tttacgcagt accgttcccg tcgcgcttaa ttttattgac gcccccatgc
    26161 aaaaaaacca caccgccaga atgggcaccg taccggtaat catcccgttg gtgaatgatc
    26221 caaaatattt ccccgccccc ggcgagaagg tgtggcacag tgcgccaagg aatagcggga
    26281 cgagcatcat cccccccggg attttctcaa tcgagcgttt tatctgcatt tccatcacct
    26341 gtcggcatat ttttaagggc tgatgcgtaa ttcctcaatg gagcatcagt gttgatggaa
    26401 acgaagatag acattcattt aatcaataaa agtgatcaaa accacatcaa ttgaaacgct
    26461 gttttatttt tatcggatca ttgtttttat tttgaaattg atcacaaaaa aaccaccgcc
    26521 gttggcgatg gttcattttt taagctgata tgcggcctat acgcctcatt gcagcaggcg
    26581 gcaaatgatt attttttcgc cgcaaaacgt gccgctgctt cgtcccagtt caccacgttc
    26641 cagaactctt taatgtagtc cggacggcgg ttctggaatt tcaggtagta agcatgttcc
    26701 cacacatcca ggcccataat cgggaagccg gaagcgccag aaatagcttc acccatcagc
    26761 ggagaatcct ggttagcagt agaaaccacc gccagtttat cgcctttcag caccagccat
    26821 gcccagccgg aaccaaagcg ggaagctgcc gctttttcaa attctgcttt gaagttatca
    26881 acggagccga agtcacgttc gatagccgct ttcaggtcac cctgcagggt ggtgcctttt
    26941 ttcagacctt tccagaacag gctgtggtta gcgtgaccgc cagcgttgtt gcgcagtacg
    27001 gttttcttgt ctgctggcag ctggtccagt ttggtgatca gctcttcaac cggcaggttg
    27061 gcaaattctg gcaggctttc cagcgccgcg ttggcgttgt ttacgtaggt ctgatggtgt
    27121 ttggtgtggt ggatttccat ggtctgctta tcgaagtgcg gttccagggc atcgtaagca
    27181 tacggcaggg atggcagggt atagctcata ttcatctcca gtattgtcgg gcggccgatt
    27241 gttaatgccg cgtaagcagt tggttcatta tagttaatta aatgatattg aaaatgatta
    27301 tcaatgccgt acttttcgta agggtatggt tttgcaggaa aatgcccgag atgtgaagca
    27361 aatcacccac ttaatgccgt gattgccagt aaatcgacaa cggcggcaac aggcgaaagg
    27421 ttaatcgaca gcacgatttt tacactcatc tcgtcggaga tgtgacgcga cgaaaaatga
    27481 tgaggataag aagatgagta acgcgattac gatggggata ttttggcatt tgatcggcgc
    27541 ggccagtgca gcctgttttt acgctccgtt caaaaaagta aaaaaatggt catgggaaac
    27601 catgtggtca gtcggtggga ttgtttcgtg gattattctg ccgtgggcca tcagcgccct
    27661 gttactaccg aatttctggg cgtattacag ctcgtttagt ctctctacgc tactgcctgt
    27721 ttttctgttc ggcgctatgt gggggatcgg taatatcaac tacggcctga ccatgcgtta
    27781 tctcggcatg tcgatgggaa ttggcatcgc cattggcatt acgttgattg tcggtacgct
    27841 gatgacgcca attatcaacg gcaatttcga tgtgttgatt agcaccgaag gcggacgcat
    27901 gacgttgctc ggcgttctgg tggcgctgat tggcgtaggg attgtaactc gcgccgggca
    27961 gttgaaagag cgcaagatgg gcattaaagc cgaagagttc aatctgaaaa aagggctggt
    28021 gctggcggtg atgtgcggca ttttctctgc cgggatgtcc tttgcgatga acgccgcaaa
    28081 accgatgcat gaagccgctg ccgcacttgg cgtcgatcca ctgtatgtcg ctctgccaag
    28141 ctatgttgtc atcatgggcg gcggcgcgat cattaacctc ggtttctgtt ttattcgtct
    28201 ggcaaaagtg aaggatttgt cgctaaaagc cgacttctcg ctggcaaaat cgctgatcat
    28261 tcacaatgtg ttactctcga cactgggcgg gttgatgtgg tatctgcaat tctttttcta
    28321 tgcctggggc cacgcccgca ttccggcgca gtatgactac atcagttgga tgctgcatat
    28381 gagtttctat gtattgtgcg gcggtatcgt cgggctggtg ctgaaagagt ggaacaatgc
    28441 aggacgccgt ccggtaacgg tgttgagcct cggttgtgtg gtgattattg tcgccgctaa
    28501 catcgtcggc atcggcatgg cgaattaatc tttctgcgaa ttgagatgac gccactggct
    28561 gggcgtcatc ccggtttccc gggtaaacac caccgaaaaa tagttactat cttcaaagcc
    28621 acattcggtc gaaatatcac tgattaacag gcggctatgc tggagaagat attgcgcatg
    28681 acacactctg acctgtcgca gatattgatt gatggtcatt ccagtctgct ggcgaaattg
    28741 ctgacgcaaa acgcgctcac tgcacgatgc ctcatcacaa aatttatcca gcgcaaaggg
    28801 acttttcagg ctagccgcca gccgggtaat cagcttatcc agcaacgttt cgctggatgt
    28861 tggcggcaac gaatcactgg tgtaacgatg gcgattcagc aacatcacca actgcccgaa
    28921 cagcaactca gccatttcgt tagcaaacgg cacatgctga ctactttcat gctcaagctg
    28981 accgataacc tgccgcgcct gcgccatccc catgctacct aagcgccagt gtggttgccc
    29041 tgcgctggcg ttaaatcccg gaatcgcccc ctgccagtca agattcagct tcagacgctc
    29101 cgggcaataa ataatattct gcaaaaccag atcgttaacg gaagcgtagg agtgtttatc
    29161 gtcagcatga atgtaaaaga gatcgccacg ggtaatgcga taagggcgat cgttgagtac
    29221 atgcaggcca ttaccgcgcc agacaatcac cagctcacaa aaatcatgtg tatgttcagc
    29281 aaagacatct tgcggataac ggtcagccac agcgactgcc tgctggtcgc tggcaaaaaa
    29341 atcatctttg agaagtttta actgatgcgc caccgtggct acctcggcca gagaacgaag
    29401 ttgattattc gcaatatggc gtacaaatac gttgagaaga ttcgcgttat tgcagaaagc
    29461 catcccgtcc ctggcgaata tcacgcggtg accagttaaa ctctcggcga aaaagcgtcg
    29521 aaaagtggtt actgtcgctg aatccacagc gataggcgat gtcagtaacg ctggcctcgc
    29581 tgtggcgtag cagatgtcgg gctttcatca gtcgcaggcg gttcaggtat cgctgaggcg
    29641 tcagtcccgt ttgctgctta agctgccgat gtagcgtacg cagtgaaaga gaaaattgat
    29701 ccgccacggc atcccaattc acctcatcgg caaaatggtc ctccagccag gccagaagca
    29761 agttgagacg tgatgcgctg ttttccaggt tctcctgcaa actgctttta cgcagcaaga
    29821 gcagtaattg cataaacaag atctcgcgac tggcggtcga gggtaaatca ttttcccctt
    29881 cctgctgttc catctgtgca accagctgtc gcacctgctg caatacgctg tggttaacgc
    29941 gccagtgaga cggatactgc ccatccagct cttgtggcag caactgattc agcccggcga
    30001 gaaactgaaa tcgatccggc gagcgataca gcacattggt cagacacaga ttatcggtat
    30061 gttcatacag atgccgatca tgatcgcgta cgaaacagac cgtgccaccg gtgatggtat
    30121 agggctgccc attaaacaca tgaatacccg tgccatgttc gacaatcaca atttcatgaa
    30181 aatcatgatg atgttcagga aaatccgcct gcgggagccg gggttctatc gccacggacg
    30241 cgttaccaga cggaaaaaaa tccacactat gtaatacggt catactggcc tcctgatgtc
    30301 gtcaacacgg cgaaatagta atcacgaggt caggttctta ccttaaattt tcgacggaaa
    30361 accacgtaaa aaacgtcgat ttttcaagat acagcgtgaa ttttcaggaa atgcggtgag
    30421 catcacatca ccacaattca gcaaattgtg aacatcatca cgttcatctt tccctggttg
    30481 ccaatggccc attttcctgt cagtaacgag aaggtcgcga attcaggcgc tttttagact
    30541 ggtcgtaatg aaattcagca ggatcacatt atgacctttc gcaattgtgt cgccgtcgat
    30601 ctcggcgcat ccagtgggcg cgtgatgctg gcgcgttacg agcgtgaatg ccgcagcctg
    30661 acgctgcgcg aaatccatcg ttttaacaat gggctgcata gtcagaacgg ctatgtcacc
    30721 tgggatgtgg atagccttga aagtgccatt cgccttggat taaacaaggt gtgcgaggaa
    30781 gggattcgta tcgatagcat tgggattgat acctggggcg tggactttgt gctgctcgac
    30841 caacagggtc agcgtgtggg cctgcccgtt gcttatcgcg atagccgcac caatggccta
    30901 atggcgcagg cacaacaaca actcggcaaa cgcgatattt atcaacgtag cggcatccag
    30961 tttctgccct tcaatacgct ttatcagttg cgtgcgctga cggagcaaca acctgaactt
    31021 attccacaca ttgctcacgc tctgctgatg ccggattact tcagttatcg cctgaccggc
    31081 aagatgaact gggaatatac caacgccacg accacgcaac tggtcaatat caatagcgac
    31141 gactgggacg agtcgctact ggcgtggagc ggggccaaca aagcctggtt tggtcgcccg
    31201 acgcatccgg gtaatgtcat aggtcactgg atttgcccgc agggtaatga gattccagtg
    31261 gtcgccgttg ccagccatga taccgccagc gcggttatcg cctcgccgtt aaacggctca
    31321 cgtgctgctt atctctcttc tggcacctgg tcattgatgg gcttcgaaag ccagacgcca
    31381 tttaccaatg acacggcact ggcagccaac atcaccaatg aaggcggggc ggaaggtcgc
    31441 tatcgggtgc tgaaaaatat tatgggctta tggctgcttc agcgagtgct tcaggagcag
    31501 caaatcaacg atcttccggc gcttatctcc gcgacacagg cacttccggc ttgccgcttc
    31561 attatcaatc ccaatgacga tcgctttatt aatcctgaga cgatgtgcag cgaaattcag
    31621 gctgcgtgtc gggaaacggc gcaaccgatc ccggaaagtg atgctgaact ggcgcgctgc
    31681 attttcgaca gtctggcgct gctgtatgcc gatgtgttgc atgagctggc gcagctgcgc
    31741 ggtgaagatt tctcgcaact gcatattgtc ggcggaggct gccagaacac gctgctcaac
    31801 cagctatgcg ccgatgcctg cggtattcgg gtgatcgccg ggcctgttga agcctcgacg
    31861 ctcggcaata tcggcatcca gttaatgacg ctggatgaac tcaacaatgt ggatgatttc
    31921 cgtcaggtcg tcagcaccac cgcgaatctg accaccttta cccctaatcc tgacagtgaa
    31981 attgcccact atgtggcgca gattcactct acacgacaga caaaggagct ttgcgcatga
    32041 ccactcaact ggaacaggcc tgggagctag cgaaacagcg tttcgcggcg gtggggattg
    32101 atgtcgagga ggcgctgcgc caacttgatc gtttacccgt ttcaatgcac tgctggcagg
    32161 gcgatgatgt ttccggtttt gaaaacccgg aaggttcgct gaccgggggg attcaggcca
    32221 caggcaatta tccgggcaaa gcgcgtaatg ccagtgagct acgtgccgat ctggaacagg
    32281 ctatgcggct gattccgggg ccgaaacggc ttaatttaca tgccatctat ctggaatcag
    32341 atacgccagt ctcgcgcgac cagatcaaac cagagcactt caaaaactgg gttgaatggg
    32401 cgaaagccaa tcagctcggt ctggatttta acccctcctg cttttcgcat ccgctaagcg
    32461 ccgatggctt tacgctttcc catgccgacg acagcattcg ccagttctgg attgatcact
    32521 gcaaagccag ccgtcgcgtt tcggcctatt ttggcgagca actcggcaca ccatcggtga
    32581 tgaacatctg gatcccggat ggtatgaaag atatcaccgt tgaccgtctc gccccgcgtc
    32641 agcgtctgct ggcagcactg gatgaggtga tcagcgagaa gctaaaccct gcgcaccata
    32701 tcgacgccgt tgagagcaaa ttgtttggca ttggcgcaga gagctacacg gttggctcca
    32761 atgagtttta catggggtat gccaccagcc gccagactgc gctgtgcctg gacgccgggc
    32821 acttccaccc gactgaagtg atttccgaca agatttccgc cgccatgctg tatgtgccgc
    32881 agttgctgct gcacgtcagc cgtccggttc gctgggacag cgatcacgta gtgctgctgg
    32941 atgatgaaac ccaggcaatt gccagtgaga ttgtgcgtca cgatctgttt gaccgggtgc
    33001 atatcggcct tgacttcttc gatgcctcta tcaaccgcat tgccgcgtgg gtcattggta
    33061 cacgcaatat gaaaaaagcc ctgctgcgtg cgttgctgga acctaccgct gagctgcgca
    33121 agctggaagc ggcgggcgat tacactgcgc gtctggcact gctggaagag cagaaatcgt
    33181 tgccgtggca ggcggtctgg gaaatgtatt gccaacgtca cgatacgcca gcaggtagcg
    33241 aatggctgga gagcgtgcgg gcttatgaga aagaaatttt gagtcgccgc gggtaaacac
    33301 tgccggatgc ggcgcgagcg ccttatccgg cctacgggtc ggcaacagtt gtaggcctga
    33361 taagacgcga cagcgtcgca tcaggcattg attgccggat gcggcacaag tgccttatcc
    33421 ggcctacagg tcggcaatag ttgtaggcct gataagacgc gacagcgtcg catcaggcat
    33481 tgattgccgg atgcggcaca agtgccttat ccggcctaca ggtcggcaac agttgtaggc
    33541 ctgataagac gcgacagcgt cgcatcaggc attgattgcc ggatgcggca caagtgcctt
    33601 atcaggccta caggtcggca atagttgtag gcctgataag acgcgacagc gtcgcatcag
    33661 gcattgattg ccggatgcgg cgcgagcgcc ttatccggcc tacgggtcgt gcatccgaca
    33721 acaccgaatt tacaggaaca cagaacatgc aaaacattac tcagtcctgg tttgtccagg
    33781 gaatgatcaa agccaccacc gacgcctggc tgaaaggctg ggatgagcgc aacggcggca
    33841 acctgacgct acgcctggat gacgccgata tcgcaccata tcacgacaat ttccaccaac
    33901 aaccgcgcta tatcccgctc agccagccca tgcctttact ggcaaataca ccgtttattg
    33961 tcaccggctc gggcaaattc ttccgtaacg tccagcttga tcctgcggct aacttaggca
    34021 tcgtaaaagt cgacagcgac ggcgcgggct accacattct ttgggggtta accaacgaag
    34081 ccgtccccac ttccgaactt ccggctcact tcctttccca ctgcgagcgc attaaagcca
    34141 ccaacggcaa agatcgggtg atcatgcact gccacgccac caacctgatc gccctcacct
    34201 atgtacttga aaacgacacc gcggtcttca ctcgccaact gtgggaaggc agcaccgagt
    34261 gtctggtggt attcccggat ggcgttggca ttttgccgtg gatggtgccc ggcacggacg
    34321 aaatcggcca ggcgaccgca caagagatgc aaaaacattc gctggtgttg tggcccttcc
    34381 acggcgtctt cggcagcgga ccgacgctgg atgaaacctt cggtttaatc gacaccgcag
    34441 aaaaatcagc acaagtatta gtgaaggttt attcgatggg cggcatgaaa cagaccatca
    34501 gccgtgaaga gttgatagcg ctcggcaagc gtttcggcgt tacgccactc gccagtgcgc
    34561 tggcgctgta aggagcaaac atgatccgca aagcctttgt catgcaggta aaccccgacg
    34621 cccacgaaga gtatcagcgt cggcataatc ccatctggcc agaactggaa gcagtgctga
    34681 aatctcacgg tgcgcataac tacgccatct atctcgacaa agcgcgtaat ctgctgtttg
    34741 ccatggtaga gattgaatct gaagaacgct ggaatgcggt tgccagcact gatgtttgcc
    34801 aacgttggtg gaaatatatg accgatgtta tgcccgctaa cccggataac agcccggtga
    34861 gtagcgagct gcaagaagtg ttttacctgc cgtaattgcc caatgtgcca gagatgcctc
    34921 cggcacaata ttttaaattt cgatttgaaa aattaaacat attacatctc ccggtaagtt
    34981 atatttccct gatacattgt gagtaaatca caaaaataat gaataaccca ttaatgattc
    35041 atgtggttta tttaaataac cattatgtgc attactccgc aaatctgacc tttcactctg
    35101 tctcaaattg tcattgttta ccgacatatc gcctctcatc acttaatcgc tccaccatta
    35161 caattgatta aaatatattt tatggagtcc gattaatggc agctcttact gcaagctgta
    35221 ttgacctgaa tattcagggc aatggcgctt attccgttct gaagcagttg gcgacaatag
    35281 cgttacaaaa cggttttatc accgactcac accagttcct gcaaaccctg ctgctgcgcg
    35341 aaaaaatgca ctctactgga tttggttccg gtgtcgccgt gccgcacggt aaaagcgcct
    35401 gcgttaaaca accgttcgta ttattcgccc gcaaagcgca ggctattgac tggaaagcca
    35461 gcgatggcga agacgtcaat tgctggatct gcctcggcgt gccgcaaagc ggcgaagagg
    35521 atcaggtcaa aatcatcggc acactgtgtc gcaaaattat tcacaaggaa tttattcatc
    35581 aactgcaaca gggcgatacc gaccaggtgc ttgccttgtt aaatcaaacc ctcagctcat
    35641 aaggaagtgg cgatggagtc atccttacgt attgtcgcga tcaccaactg ccccgccggg
    35701 atcgctcaca cctacatggt ggcggaagcc ctggaacaga aagcccgttc tctcggtcat
    35761 accataaaag tggaaactca agggtccagt ggcgttgaaa accgcttatc cagcgaagag
    35821 attgccgctg ccgattacgt cattctcgct accgggcgtg gcctgagcgg tgatgatcgc
    35881 gcgcggtttg ccgggaagaa agtttatgag attgccatct cccaggcgtt gaaaaatatc
    35941 gaccagattt tcagcgaatt accgacaaac tcgcagcttt ttgccgcaga tagcggcgtg
    36001 aagcttggca aacaggaagt gcaaagcggt agcgtgatga gccacctgat agcgggcgtc
    36061 tctgcggcgc tgccgtttgt catcggcggt ggtatcctgg tggcgcttgc caacatgctg
    36121 gtgcagttcg gtttgccgta taccgatatg tcgaaaggcg cgccgtcgtt tacctgggta
    36181 gttgaatcca tcggttacct tggcttcacc tttatgatcc ccatcatggg cgcttatatt
    36241 gcctcgtcga ttgccgataa accggctttc gctccggcgt ttctggtttg ctatctggcg
    36301 aacgacaaag cgctgctcgg cacccagtcg ggtgcgggat tcctcggcgc ggtggtgctg
    36361 gggctggcga ttggctattt cgtcttctgg ttccgcaaag tgcgccttgg caaagcatta
    36421 caaccgctgc tcggttcaat gctgatcccg ttcgttactc tgctggtttt cggcgtgctc
    36481 acttactacg ttatcgggcc ggtgatgtcc gacctcatgg gcgggctgct ccacttcctg
    36541 aataccattc ctccatcaat gaagtttgcg gcagcgtttc tggtcggtgc gatgctggcg
    36601 ttcgatatgg gcggccccat caataaaacc gcctggttct tctgcttctc actgctggaa
    36661 aaacacattt atgactggta cgccatcgtc ggcgttgtcg cgctgatgcc gcccgtcgcg
    36721 gcgggtcttg cgacgttcat tgcgcccaaa ctgtttaccc gacaggaaaa agaggctgcc
    36781 agtagtgcca ttgtggtcgg tgccacagtc gcaaccgaac cggctattcc ttacgctctg
    36841 gcagctccgt tgccgatgat taccgccaat acgctggcgg gcggcattac cggcgtgctg
    36901 gtgatcgctt tcggaatcaa acgtctggca cctggtttgg gtatctttga cccgctgatc
    36961 ggcctgatgt cgccggtggg ttcgttttat ctggtgctgg cgattggcct cgcgctgaac
    37021 atttcattca ttatcgtcct gaaaggattg tggttacgcc gcaaagcgaa agccgcgcaa
    37081 caggagcttg tccatgaaca ttgagttact gcaacagttg tgcgaagcca gcgccgtcag
    37141 cggcgatgaa caggaagttc gcgacattct gataaacacg ctggaacctt gcgtgaatga
    37201 aatcaccttc gatggtctgg gcagctttgt tgcccgtaag gggaataaag gtccaaaagt
    37261 tgccgttgtc ggacatatgg atgaagtcgg ctttatggtc acccacatcg acgagagcgg
    37321 ttttctgcgt tttaccacca ttggcggctg gtggaatcag tcgatgctca accaccgggt
    37381 aaccatacgc acacacaagg gagtgaaaat ccctggtgtg attggttccg tcgcgcctca
    37441 tgcgttaacg gaaaagcaaa agcaacaacc gctgtcattt gatgagatgt tcattgatat
    37501 tggcgcgaac agtcgcgaag aggtggaaaa gcgcggcgtg gaaattggta attttattag
    37561 cccggaagcc aattttgcct gctggggcga agataaagtg gtcggcaagg cgttggataa
    37621 ccgcatcggc tgcgcaatga tggctgaact attgcagacg gtgaataatc ccgaaattac
    37681 gctgtatggc gttggcagtg tggaagaaga agttgggcta cgcggggcgc aaacctcggc
    37741 ggaacacatt aaaccggacg tcgtgatcgt gttggatacc gccgtagcgg gcgatgttcc
    37801 gggcattgat aacattaaat acccgctgaa actgggccag gggccggggc tgatgctgtt
    37861 tgacaagcgc tacttcccca accagaaact ggtagcagtg ttaaaaagct gtgccgcaca
    37921 taacgattta ccgctgcaat tttccaccat gaaaaccggt gcgacggatg gcgggcgcta
    37981 caacgtgatg ggcggcgggc gtccggttgt cgcgctgtgt ctgccaactc gttatctgca
    38041 cgccaacagc ggtatgattt caaaagccga ttacgaagct ctgctcacgc tgatacgggg
    38101 ttttctgacg accttaactg cggagaaagt caacgcgttt agccagttcc gtcaggtgga
    38161 ttaatgctaa acgaacgcca gttaaagatt gtcgatctgc tggagcaaca gccgcgcacg
    38221 cctggcgagc tggcgcaaca gactggcgtt tcaggcagga ccatcctgcg tgatattgac
    38281 tatctcaact tcacccttaa cggcaaagcc cgcattttcg ccagtggcag tgcgggctat
    38341 cagctggaaa tcttcgagcg ccgcagcttt tttcagttgc tgcaaaagca cgataacgac
    38401 gatcggctgc tggcgctgtt attactgaat actttcactc cccgtgcgca actcgcctcg
    38461 gcgcttaatt tgccagaaac gtgggtagca gagcgtctgc cccggttaaa acagcgttat
    38521 gaacgcactt gttgcctggc cagccgccct ggtttgggcc atttcattga tgagacagaa
    38581 gagaaacgcg ttatcttgct ggcgaacttg ctgcgcaaag atccgttttt aattccgctg
    38641 gcgggcataa cacgagacaa ccttcagcat ttatccacgg cctgcgacaa ccaacaccgc
    38701 tggccgctca tgcagggtga ttatctctcc agcctgattc tggcgattta cgccctgcgt
    38761 aatcaactga ccgatgagtg gccgcaatat cccggtgacg agataaaaca aatcgttgaa
    38821 catagcggtc tgtttcttgg tgataacgct gtaagaaccc tgacgggttt gatagagaaa
    38881 cagcatcagc aagcgcaggt aatttcagcc gataatgtgc aggggttgct gcaaagggtg
    38941 ccgggcatcg cgtcattgaa tattattgat gcgcagctgg ttgagaatat taccgggcat
    39001 ttattacgtt gccttgccgc accagtgtgg attgctgagc accgccagag cagcatgaat
    39061 aacctgaaag ccgcctggcc tgcggccttt gatatgagtc tgcactttat tacgctactg
    39121 cgtgaacagc tcgatattcc ccttttcgac agcgatctga tcggtttgta ttttgcctgt
    39181 gcgctggagc ggcatcaaaa cgaacgccag ccgatcattt tgctctcgga ccagaacgcg
    39241 attgccacta ttaatcagct cgccattgag cgcgatgttt taaattgtcg ggtaattatt
    39301 gcccgtagct taagcgaact tgttgccatt cgcgaagaga ttgagccgtt attgatcatt
    39361 aacaacagcc attatttact ggatgacgcg gtaaataatt acatcaccgt aaaaaatatc
    39421 attacggctg ccggtatcga acaaataaaa cattttctgg cgacggcatt tattcgccaa
    39481 cagccggagc gttttttctc tgcccccgga agttttcatt attcgaatgt acgcggtgaa
    39541 agctggcaac atattacccg gcaaatttgt gcgcaattag tcgcacaaca ccatattacc
    39601 gccgatgaag cacaacgcat catcgcccgc gaaggcgaag gtgaaaacct gattgttaat
    39661 cgcctcgcca tcccacattg ctggagcgaa caggagcgac gttttcgtgg attttttatt
    39721 accctcgccc aaccagttga ggtgaataac gaagtcatta accatgtctt gatcgcctgc
    39781 gccgccgccg atgcgcgtca tgagctaaaa atatttagct atctggcaag catattgtgt
    39841 cagcatccgg cggagattat tgccgggtta acaggatatg aggcatttat ggagttactt
    39901 cacaaggggt gaactgtgtc ggatgcgccg catccgacac tgcatttatc atcaaaaacg
    39961 tttaacgcag gctattatag tcatcaacca tttcgttgta ctcgcgtaat gctctcggga
    40021 aagagtcttc gaccatccag cttgagtttg cgtcctgaag ttgctcttta tcccagtcag
    40081 agtacgggac tttatctctg atgcggcgaa cgtatttttt agcctcgagt tgatactggc
    40141 ctgccgaatt aataaacgag aaattcatgc cgcctttatc cgcttctttg gcctgcgcca
    40201 ctagcgtttc cagttcagac actttcttca ttgccgcttc tgcatcaaac ttatcttgcg
    40261 atatcaggtt attaatttgt ttcgctgaaa tcatgactgc cagagagtag tagtggaatg
    40321 ttttcccttc tctttcttca atatttttca gttccgcaag ctgacgctta tcattaattt
    40381 cctgaatcgc cgcatgataa gattcggcta caggttcaaa ggcttccaga ttttttaaga
    40441 atgtctggtg cagcgttttc cctttcgcaa acgcatcgtc tttataattt tcctgggtgt
    40501 aatatttatc catttcgtta atggtattac ccaacgccac ggcagcatcg atataactca
    40561 ccgccacgcc atcaattggt tgcagcgcag gcgttaacgc cacagcactt tttacgcctt
    40621 tttcacactc agcgaggttg gattcactaa tgccgtagat gccataaaca gtacgctctt
    40681 caccggtagg cccctgttta aaatctttca gccagtcagc ataacgcgcc agactgcgct
    40741 gtaccgggat ctgtaacttg ttgtagcact tgatatagac atccattttt tcgtcgaaaa
    40801 ccgcttgttc atcgaccacc ggttgcgcag gtgtttcagg tttagcttct gcttttgcaa
    40861 cgggagcttc agtaggtttc gcttcaggag ctggtgcggc aggttgacta ttggcaggcg
    40921 ggagcgtttc tgtttcggct tttttatcat cacaacccgt cagaccgagg gacatgatgg
    40981 cgactataat agcggaagat aataaattcc ttttcattta a
//
LOCUS       DAPOAV010000036        39416 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.036, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000036 DAPOAV010000000
VERSION     DAPOAV010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 39416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39416
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.036"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            233..1888
                     /gene="aslA"
                     /locus_tag="RN951_002161"
     CDS             233..1888
                     /gene="aslA"
                     /locus_tag="RN951_002161"
                     /EC_number="3.1.6.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase AslA"
                     /protein_id="HDX2527160.1"
                     /translation="MEFSFSPKRLVVAVAAALPLMASAADTPSTATARKGFAGYDHPN
                     QYLVKPATTIADNMMPVMQHPAQDKETQQKLAELEKKTGKKPNVVVFLLDDVGWMDVG
                     FNGGGVAVGNPTPDIDAVASQGLILTSAYSQPSSSPTRATILTGQYSIHHGILMPPMY
                     GQPGGLQGLTTLPQLLHDQGYVTQAIGKWHMGENKESQPQNVGFDDFRGFNSVSDMYT
                     EWRDVHVNPEVALSPDRSEYIKQLPFSKDDVHAVRGGEQQAIADITPKYMEDLDQRWM
                     DYGVKFLDKMAKSDKPFFLYYGTRGCHFDNYPNAKYAGSSPARTSYGDCMVEMNDVFA
                     NLYKTLEKNGQLDNTLIVFTSDNGPEAEVPPHGRTPFRGAKGSTWEGGVRVPTFVYWK
                     GMIQPRKSDGIVDLADLFPTALDLAGHPGAKVANLVPKTTFIDGVDQTSFFLGTNGQS
                     NRKAEHYFLNGKLAAVRMDEFKYHVLIQQPYAYTQSGYQGGFTGTVMQTAGSSVFNLY
                     TDPQESDSIGVRHIPMGVPLQTEMHAYMEILKKYPPRAQIKSD"
     gene            complement(2047..3282)
                     /locus_tag="RN951_002162"
     CDS             complement(2047..3282)
                     /locus_tag="RN951_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase AslB"
                     /protein_id="HDX2527161.1"
                     /translation="MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTH
                     MDDDTLEAYVRHYIAASEPQNEVAFTWQGGEPTLLGLAFYRRAVALQAKYGAGRKISN
                     SFQTNGVLLDDEWCAFLAEHHFLVGLSLDGPPEIHNQYRVTKGGRPTHKLVMRALTLL
                     QKHHVDYNVLVCVNRTSAQQPLQVYDFLCDAGVEFIQFIPVVERLADETTARDGLKLH
                     APGDIQGELTEWSVRPEEFGEFLVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVC
                     HHQPTCGRSVIVEHNGDVYACDHYVYPQYRLGNMHQQTIAEMIDSPQQQAFGEDKFKQ
                     LPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMADLL
                     AHGRPASDIMHAHLLVVSK"
     gene            complement(3429..3505)
                     /locus_tag="RN951_002163"
     tRNA            complement(3429..3505)
                     /locus_tag="RN951_002163"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3469..3471),aa:Pro,seq:tgg)
     gene            complement(3548..3634)
                     /locus_tag="RN951_002164"
     tRNA            complement(3548..3634)
                     /locus_tag="RN951_002164"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3598..3600),aa:Leu,seq:cag)
     gene            complement(3655..3730)
                     /locus_tag="RN951_002165"
     tRNA            complement(3655..3730)
                     /locus_tag="RN951_002165"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3695..3697),aa:His,seq:gtg)
     gene            complement(3789..3865)
                     /locus_tag="RN951_002166"
     tRNA            complement(3789..3865)
                     /locus_tag="RN951_002166"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3829..3831),aa:Arg,seq:ccg)
     gene            complement(3968..5353)
                     /locus_tag="RN951_002167"
     CDS             complement(3968..5353)
                     /locus_tag="RN951_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDX2527162.1"
                     /translation="MADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPS
                     VLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMA
                     VGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTT
                     IIVMIVIGLGVIFFGFGNGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVEL
                     IGITAGEAKNPQVTLRSAVGKVLWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFA
                     KIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPAAMAKVSRHGVPVA
                     GVAVSIAILLIGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAA
                     IASHPFRSILFPWANYVTMAFLICVLIGMYFNEDTRMSLFVGIIFMLAVTAIYKVFGL
                     NRHGKAHKLEE"
     gene            complement(5544..6284)
                     /gene="rffM"
                     /locus_tag="RN951_002168"
     CDS             complement(5544..6284)
                     /gene="rffM"
                     /locus_tag="RN951_002168"
                     /EC_number="2.4.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide
                     N-acetylmannosaminouronosyltransferase"
                     /protein_id="HDX2527163.1"
                     /translation="MNNNTTAPTYTLRGLQLIGWRDMQHALDYLFADGQLKQGTLVAI
                     NAEKMLTIEDNAEVRELINAAEFKYADGISVVRSVRKKYPQAQVSRVAGADLWEELMA
                     RAGKEGTPVFLVGGKPEVLAQTEAKLRNQWNVNIVGSQDGYFKPEQRQALFERIHASG
                     AQIVTVAMGSPKQEIIMRDCRLVHPDALYMGVGGTYDVFTGHVKRAPKIWQTLGLEWL
                     YRLLSQPSRIKRQLRLLRYLRWHYTGNL"
     gene            complement(6287..7639)
                     /gene="wzyE"
                     /locus_tag="RN951_002169"
     CDS             complement(6287..7639)
                     /gene="wzyE"
                     /locus_tag="RN951_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECA oligosaccharide polymerase"
                     /protein_id="HDX2527164.1"
                     /translation="MSLLQFSGLFVVWLLCTLFIATLTWFEFRRVRFNFNVFFSLLFL
                     LTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAGCFYAVYYVTYKTRLRKRVADVPR
                     RPLFTMNRVETNLTWVILMGIALVSVGIFFMHNGFLLFRLNSYSQIFSSEVSGVALKR
                     FFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIG
                     IIRGWISLWMLAAAGVLGIVGMFWLALKRYGMNVSGDEAFYTFLYLTRDTFSPWENLA
                     LLLQNYDNIDFQGLAPIVRDFYVFIPSWLWPGRPSMVLNSANYFTWEVLNNHSGLAIS
                     PTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNREPNRYKAAILHSFCFGAIF
                     NMIVLAREGLDSFVSRVVFFIVVFGACLMIAKLLYWLFESAGLIHKRTKSSLRTQVEG
                     "
     gene            complement(7636..8715)
                     /gene="rffT"
                     /locus_tag="RN951_002170"
                     /gene_synonym="wecF"
     CDS             complement(7636..8715)
                     /gene="rffT"
                     /locus_tag="RN951_002170"
                     /gene_synonym="wecF"
                     /EC_number="2.4.1.325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDP-N-acetylfucosamine:lipid II
                     N-acetylfucosaminyltransferase"
                     /protein_id="HDX2527165.1"
                     /translation="MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDD
                     GLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRFFFHGQFNPTLWLALLSGGIKPS
                     QFFWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGEL
                     LFFPTRMDPSLNTMANDRQREGKMTILVGNSGDRSNEHIAALRAVHQQFGDTVKVVVP
                     MGYPPNNEAYIEEVRQAGLELFSEENLQILSEKLEFDAYLALLRQCDLGYFIFARQQG
                     IGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLASVDKN
                     TIAFFSPNYLQGWQRALAIAAGEVA"
     gene            complement(8712..9962)
                     /gene="wzxE"
                     /locus_tag="RN951_002171"
     CDS             complement(8712..9962)
                     /gene="wzxE"
                     /locus_tag="RN951_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid III flippase WzxE"
                     /protein_id="HDX2527166.1"
                     /translation="MSLAKASLWTAASTLVKIGAGLLVGKLLAVSFGPAGLGLAANFR
                     QLITVLGVLAGAGIFNGVTKYVAQYHDNPQQLRRVVGTSSAMVLGFSTLMALVFVLAA
                     APISQGLFGNTDYQGLVRLVALVQMGIAWGNLLLALMKGFRDAAGNALSLIVGSLIGV
                     LAYYVSYRLGGYEGALLGLALIPALVVIPAAIMLIKRGVIPLSYLKPSWDNGLAGQLS
                     KFTLMALITSVTLPVAYIMMRKLLAAQYSWDEVGIWQGVSSISDAYLQFITASFSVYL
                     LPTLSRLTEKRDITREVVKSLKFVLPAVAAASFTVWLLRDFAIWLLLSNKFTAMRDLF
                     AWQLVGDVLKVGAYVFGYLVIAKASLRFYILAEVSQFTLLMVFAHWLIPAHGALGAAQ
                     AYMATYIVYFSLCCGVFLLWRRRA"
     gene            complement(9964..11094)
                     /gene="rffA"
                     /locus_tag="RN951_002172"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
     CDS             complement(9964..11094)
                     /gene="rffA"
                     /locus_tag="RN951_002172"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
                     /EC_number="2.6.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-amino-4,6-dideoxygalactose transaminase"
                     /protein_id="HDX2527167.1"
                     /translation="MIPFNAPPVVGTELDYMQSAMGSGKLCGDGGFTRRCQQWLEQRF
                     GSAKVLLTPSCTASLEMAALLLDIQPGDEVIMPSYTFVSTANAFVLRGAKIVFVDVRP
                     DTMNIDETLIEAAITDKTRVIVPVHYAGVACEMDTIMALAKKHNLFVVEDAAQGVMST
                     YKGRALGTIGHIGCFSFHETKNYTAGGEGGATLINDKALIERAEIIREKGTNRSQFFR
                     GQVDKYTWRDIGSSYLMSDLQAAYLWAQLEAADRINQQRLALWQNYYDALAPLAKAGR
                     IELPSIPDGCVQNAHMFYIKLRDIDDRSALINFLKEAEIMAVFHYIPLHGCPAGEHFG
                     EFHGEDRYTTKESERLLRLPLFYNLSPVNQRTVIATLLNYFS"
     gene            complement(11099..11773)
                     /gene="rffC"
                     /locus_tag="RN951_002173"
                     /gene_synonym="wecD"
     CDS             complement(11099..11773)
                     /gene="rffC"
                     /locus_tag="RN951_002173"
                     /gene_synonym="wecD"
                     /EC_number="2.3.1.210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-amino-4,6-dideoxy-D-galactose
                     acyltransferase"
                     /protein_id="HDX2527168.1"
                     /translation="MPVRASIEPLTWENAFFGVNSAIVRITSEAPLLTPDALAPWSRV
                     QAKIAASNTGELDALQQLGFSLVEGEVDLALPVNNASDSGAVVAQETDIPALRQLASA
                     AFAQSRFRAPWYAPDASSRFYAQWIENAVRGTFDHQCLILRAASGDIRGYVSLRELNA
                     TDARIGLLAGRGAGAELMQTALNWAYARGKTTLRVATQMGNTAALKRYIQSGANVEST
                     AYWLYR"
     gene            complement(11751..12632)
                     /gene="rfbA"
                     /locus_tag="RN951_002174"
     CDS             complement(11751..12632)
                     /gene="rfbA"
                     /locus_tag="RN951_002174"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HDX2527169.1"
                     /translation="MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLA
                     GIREILIITTPEDKGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS
                     CLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEK
                     PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRG
                     FAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT
                     GYGQYLLELLRARPRQY"
     gene            complement(12651..13718)
                     /gene="rffG"
                     /locus_tag="RN951_002175"
     CDS             complement(12651..13718)
                     /gene="rffG"
                     /locus_tag="RN951_002175"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HDX2527170.1"
                     /translation="MRKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSL
                     APVAQSERFAFEKVDICDRAELARVFTEHQPDCVMHLAAESHVDRSIDGPAAFIETNI
                     VGTYTLLEAARAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPY
                     SASKASSDHLVRAWLRTYGLPTLITNCSNNYGPYHFPEKLIPLMILNALAGKSLPVYG
                     NGQQIRDWLYVEDHARALYCVATTGKVGETYNIGGHNERKNLDVVETICELLEELAPN
                     KPHGVAHYRDLITFVADRPGHDLRYAIDASKIARELGWLPQETFESGMRKTVQWYLAN
                     ESWWKQVQDGSYQGERLGLKG"
     gene            complement(13718..14980)
                     /gene="wecC"
                     /locus_tag="RN951_002176"
     CDS             complement(13718..14980)
                     /gene="wecC"
                     /locus_tag="RN951_002176"
                     /EC_number="1.1.1.336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetyl-D-mannosamine dehydrogenase"
                     /protein_id="HDX2527171.1"
                     /translation="MSFATISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINR
                     GEIHIVEPDLASVVKTAVEGGFLRASTTPVEADAWLIAVPTPFKGDHEPDMTYVESAA
                     RSIAPVLKKGALVILESTSPVGSTEKMAEWLAEMRPDLTFPQQVGEQADVNIAYCPER
                     VLPGQVMVELIKNDRVIGGMTPVCSARASELYKIFLEGECVVTNSRTAEMCKLTENSF
                     RDVNIAFANELSLICADQGINVWELIRLANRHPRVNILQPGPGVGGHCIAVDPWFIVA
                     QNPQQARLIRTAREVNDHKPFWVIDQVKAAVADCLAATDKRASELKIACFGLAFKPNI
                     DDLRESPAMEIAELIAQWHSGETLVVEPNIHQLPKKLTGLCTLAQLDEALATADVLVM
                     LVDHSQFKVINGDNVHQQYVVDAKGVWR"
     gene            complement(14977..16107)
                     /gene="wecB"
                     /locus_tag="RN951_002177"
     CDS             complement(14977..16107)
                     /gene="wecB"
                     /locus_tag="RN951_002177"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HDX2527172.1"
                     /translation="MKVLTVFGTRPEAIKMAPLVHALAKDPFFEAKVCVTAQHREMLD
                     QVLKLFSIVPDYDLNIMQPGQGLTEITCRILEGLKPILAEFKPDVVLVHGDTTTTLAT
                     SLAAFYQRIPVGHVEAGLRTGDLYSPWPEEANRTLTGHLAMYHFSPTETSRQNLLREN
                     VADSRIFITGNTVIDALLWVRDQVMSSDKLRSELAANYPFIDPDKKMILVTGHRRESF
                     GRGFEEICHALADIATTHQDIQIVYPVHLNPNVREPVNRILGHVKNVILIDPQEYLPF
                     VWLMNHAWLILTDSGGIQEEAPSLGKPVLVMRDTTERPEAVTAGTVRLVGTDKQRIVE
                     EVTRLLKDENEYQAMSRAHNPYGDGQACSRILEALKNNRISL"
     gene            complement(16163..17209)
                     /gene="wzzE"
                     /locus_tag="RN951_002178"
     CDS             complement(16163..17209)
                     /gene="wzzE"
                     /locus_tag="RN951_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709589.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECA polysaccharide chain length modulation
                     protein"
                     /protein_id="HDX2527173.1"
                     /translation="MTQPMPGKPAEDAENELDIRGLFRTLWAGKLWIIGMGLAFALIA
                     LAYTFFARQEWSSTAITDRPTVNMLGGYYSQQQFLRNLDVRSNMASADQPSVMDEAYK
                     EFVMQLASWDTRREFWLQTDYYKQRMVGNSKADAALLDEMINNIQFIPGDFTRAVNDS
                     VKLIAETAPDANNLLRQYVAFASQRAASHLNDELKGAWAARTIQMKAQVKRQEEVAKA
                     IYDRRMNSIEQALKIAEQHNISRSATDVPAEELPDSEMFLLGRPMLQARLENLQAVGP
                     AFDLDYDQNRAMLNTLNVGPTLDPRFQTYRYLRTPEEPVKRDSPRRAFLMIMWGIVGG
                     LIGAGVALTRRCSK"
     gene            complement(17221..18324)
                     /gene="wecA"
                     /locus_tag="RN951_002179"
     CDS             complement(17221..18324)
                     /gene="wecA"
                     /locus_tag="RN951_002179"
                     /EC_number="2.7.8.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--undecaprenyl-phosphate
                     N-acetylglucosaminephosphotransferase"
                     /protein_id="HDX2527174.1"
                     /translation="MNLLAVSTDLISIFLFTTLFLFFARKVAKKVGLVDKPNFRKRHQ
                     GLIPLVGGISVYAGICFTFGIVDYYIPHASLYLACAGVLVFIGALDDRFDISVKIRAT
                     IQAAVGIVMMVFGKLYLSSLGYIFGSWEMVLGPFGYFLTLFAVWAAINAFNMVDGIDG
                     LLGGLSCVSFAAIGMILWFDGQTSLAIWCFAMIAAILPYIMLNLGILGRRYKVFMGDA
                     GSTLIGFTVIWILLETTQGKTHPISPVTALWIIAIPLMDMVAIMYRRLRKGMSPFSPD
                     RQHIHHLIMRAGFTSRQAFVLITLAAALLASIGVLAEYSHFVPEWVMLVLFLLAFFLY
                     GYCIKRAWKVARFIKRVKRRLRRNRGGSPNLTK"
     gene            complement(18564..19823)
                     /gene="rho"
                     /locus_tag="RN951_002180"
     CDS             complement(18564..19823)
                     /gene="rho"
                     /locus_tag="RN951_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017492510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HDX2527175.1"
                     /translation="MNLTELKNTPVSELITLGENMGLENLARMRKQDIIFAILKQHAK
                     SGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIR
                     PPKEGERYFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTAR
                     VLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTE
                     MQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNT
                     VVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEE
                     FKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGE
                     IDAMEFLINKLAMTKTNDDFFEMMKRS"
     gene            complement(19908..20009)
                     /gene="rhoL"
                     /locus_tag="RN951_002181"
     CDS             complement(19908..20009)
                     /gene="rhoL"
                     /locus_tag="RN951_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rho operon leader peptide RhoL"
                     /protein_id="HDX2527176.1"
                     /translation="MRSEQISGSSLNPSCRFSSAYSPVTRQRKDMSR"
     gene            complement(20150..20479)
                     /gene="trxA"
                     /locus_tag="RN951_002182"
     CDS             complement(20150..20479)
                     /gene="trxA"
                     /locus_tag="RN951_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017375425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxA"
                     /protein_id="HDX2527177.1"
                     /translation="MSDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILD
                     EIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKE
                     FLDANLA"
     gene            20610..21875
                     /gene="rhlB"
                     /locus_tag="RN951_002183"
     CDS             20610..21875
                     /gene="rhlB"
                     /locus_tag="RN951_002183"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlB"
                     /protein_id="HDX2527178.1"
                     /translation="MSKTHLTEQKFSDFALHPKVVEALEKKGFHNCTPIQALALPLTL
                     AGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIADRKVNQPRALIMAPTRELAVQIHA
                     DAEPLAEATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQ
                     VVVLDEADRMYDLGFIKDIRWLFRRMPPANQRLNMLFSATLSYRVRELAFEQMNNAEY
                     IEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEEIWGHL
                     AADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLP
                     DDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIETYIGHSIPVSKYNPDALMTD
                     LPKPLRLTRPRTGNGPRRTGAPRNRRRSG"
     gene            22011..23495
                     /gene="gppA"
                     /locus_tag="RN951_002184"
     CDS             22011..23495
                     /gene="gppA"
                     /locus_tag="RN951_002184"
                     /EC_number="3.6.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanosine-5'-triphosphate,3'-diphosphate
                     diphosphatase"
                     /protein_id="HDX2527179.1"
                     /translation="MGSTSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAA
                     GLNSENALSNEAMERGWQCLRLFAERLQDIPPSQIRVVATATLRLAVNAGDFIAKAQE
                     ILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSL
                     SMGCVTWLERYFADRNLGQENFDAAEKAAREVLRPVADELRYHGWKVCVGASGTVQAL
                     QEIMMAQGMDERITLEKLQQLKQRAIHCGRLEELEIDGLTLERALVFPSGLAILIAIF
                     TELNIQCMTLAGGALREGLVYGMLHLAVEQDIRSRTLRNIQRRFMIDIDQAQRVAKVA
                     ANFFDQVENEWHLEAISRDLLISACQLHEIGLSVDFKQAPQHAAYLVRNLDLPGFTPA
                     QKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAIIFASRRRDDLVPEMT
                     LQANHELLTLTLPQGWLTQHPLGKEIIAQESQWQSYVHWPLEVH"
     gene            complement(23542..25563)
                     /gene="rep"
                     /locus_tag="RN951_002185"
     CDS             complement(23542..25563)
                     /gene="rep"
                     /locus_tag="RN951_002185"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase Rep"
                     /protein_id="HDX2527180.1"
                     /translation="MRLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCG
                     YQARHIAAVTFTNKAAREMKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMK
                     ANFSLFDDTDQLALLKELTEGLIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGER
                     DRIFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRERWQNKIRYLLVDEYQD
                     TNTSQYELVKLLVGSRARFTVVGDDDQSIYSWRGARPQNLVLLSQDFPALKVIKLEQN
                     YRSSGRILKAANILIANNPHVFEKRLFSELGYGAELKVLSANNEEHEAERVTGELIAH
                     HFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRV
                     LTNPDDDSAFLRIVNTPKREIGPATLKKLGEWAMTRNKSMFTASFDMGLSQTLSGRGY
                     EALTRFTHWLAEIQRLAEREPIAAVRDLIHGMDYESWLYETSPSPKAAEMRMKNVNQL
                     FSWMTEMLEGSELDEPMTLTQVVTRFTLRDMMERGESEEELDQVQLMTLHASKGLEFP
                     YVYMVGMEEGFLPHQSSIDEDNIDEERRLAYVGITRAQKELTFTLCKERRQYGELVRP
                     EPSRFLLELPQDDLIWEQERKVVSAEERMQKGQSHLANLKAMMAAKRGK"
     gene            25780..26228
                     /locus_tag="RN951_002186"
                     /pseudo
     CDS             25780..26228
                     /locus_tag="RN951_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
     gene            26427..26708
                     /gene="ppiC"
                     /locus_tag="RN951_002187"
     CDS             26427..26708
                     /gene="ppiC"
                     /locus_tag="RN951_002187"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004097481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PpiC"
                     /protein_id="HDX2527181.1"
                     /translation="MAKTAAALHILVKEEKLALDLLEQIKNGADFGKLAKKHSICPSG
                     KRGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYHIIKVLYRN"
     gene            complement(26795..28270)
                     /gene="ilvC"
                     /locus_tag="RN951_002188"
     CDS             complement(26795..28270)
                     /gene="ilvC"
                     /locus_tag="RN951_002188"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HDX2527182.1"
                     /translation="MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVG
                     CGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLV
                     INLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTE
                     VREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDL
                     MGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDR
                     LSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREET
                     GKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLH
                     ELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPE
                     GAVDNGQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG"
     gene            28420..29313
                     /gene="ilvY"
                     /locus_tag="RN951_002189"
     CDS             28420..29313
                     /gene="ilvY"
                     /locus_tag="RN951_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator IlvY"
                     /protein_id="HDX2527183.1"
                     /translation="MDLRDLKTFLHLAESRHFGRSARAMHVSPSTLSRQIQRLEEDLG
                     QPLFVRDNRTVTLTEAGEELRVFAQQTLLQYQQLRHTIDQQGPSLSGELHIFCSVTAA
                     YSHLPPILDRFRAEHPSVEIKLTTGDAADAMEKVVTGEADLAIAGKPETLPGAVAFSM
                     LENLAVVLIAPALPCPVRNQVSVEKPDWSTVPFIMADQGPVRRRIELWFRRNKISNPM
                     IYATVGGHEAMVSMVALGCGVALLPEVVLENSPEPVRNRVMILERSDEKTPFELGVCA
                     QKKRLHEPLIEAFWKILPNHK"
     gene            complement(29365..30909)
                     /gene="ilvA"
                     /locus_tag="RN951_002190"
     CDS             complement(29365..30909)
                     /gene="ilvA"
                     /locus_tag="RN951_002190"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase, biosynthetic"
                     /protein_id="HDX2527184.1"
                     /translation="MADSQPLSGAPEGAEYLRAVLRAPVYEAAQVTPLQKMEKLSSRL
                     DNVILVKREDRQPVHSFKLRGAYAMMAGLTEEQKAHGVITASAGNHAQGVAFSSARLG
                     VKALIVMPTATADIKVDAVRGFGGEVLLHGANFDEAKAKAIELSQQQGFTWVPPFDHP
                     MVIAGQGTLALELLQQDAHLDRVFVPVGGGGLAAGVAVLIKQLMPQIKVIAVEAEDSA
                     CLKAALDAGHPVDLPRVGLFAEGVAVKRIGDETFRLCQEYLDDIITVDSDAICAAMKD
                     LFEDVRAVAEPSGALALAGMKKYIALHNIRGERLAHILSGANVNFHGLRYVSERCELG
                     EQREALLAVTIPEEKGSFLKFCQLLGGRSVTEFNYRFADAKNACIFVGVRLSRGLEER
                     KEILQMLNDGGYSVVDLSDDEMAKLHVRYMVGGRPSHPLQERLYSFEFPESPGALLRF
                     LNTLGTYWNISLFHYRSHGTDYGRVLAAFELGDHEPDFETRLNELGYDCHDETNNPAF
                     RFFLAG"
     gene            complement(30912..32762)
                     /gene="ilvD"
                     /locus_tag="RN951_002191"
     CDS             complement(30912..32762)
                     /gene="ilvD"
                     /locus_tag="RN951_002191"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HDX2527185.1"
                     /translation="MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFT
                     QFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIAD
                     SVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQII
                     KLDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGN
                     GSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMG
                     GSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIG
                     ILGELDRAGLLNRDVKNVLGLTLPQTLEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFS
                     QDCRWDTLDDDRANGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTG
                     PAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKAC
                     ALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDAELA
                     ARREAQDARGDKAWTPKNRERQVSFALRAYASLATSADKGAVRDKSKLGG"
     gene            complement(32827..33756)
                     /gene="ilvE"
                     /locus_tag="RN951_002192"
     CDS             complement(32827..33756)
                     /gene="ilvE"
                     /locus_tag="RN951_002192"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain-amino-acid transaminase"
                     /protein_id="HDX2527186.1"
                     /translation="MTTKKADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYD
                     SHKGPVVFRHREHMQRLHDSAKIYRFPVSQSIDELMEACRDVIRKNNLTSAYIRPLIF
                     VGDVGMGVNPPAGYSTDVIIAAFPWGAYLGAEALEQGIDAMVSSWNRAAPNTIPTAAK
                     AGGNYLSSLLVGSEARRHGYQEGIALDVNGYISEGAGENLFEVKDGVLFTPPFTSSAL
                     PGITRDAIIKLAKELGIEVREQVLSRESLYLADEVFMSGTAAEITPVRSVDGIQVGEG
                     RCGPVTKRIQQAFFGLFTGETEDKWGWLDQVNQ"
     gene            complement(33776..34039)
                     /gene="ilvM"
                     /locus_tag="RN951_002193"
     CDS             complement(33776..34039)
                     /gene="ilvM"
                     /locus_tag="RN951_002193"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 small subunit"
                     /protein_id="HDX2527187.1"
                     /translation="MMQHQVNVSARFNPETLERVLRVVRHRGFHVCSMNMAAASDAQN
                     INIELTVASPRSVDLLFSQLNKLVDVAHVAICQSTTTSQQIRA"
     gene            complement(34036..35682)
                     /locus_tag="RN951_002194"
     CDS             complement(34036..35682)
                     /locus_tag="RN951_002194"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 catalytic subunit"
                     /protein_id="HDX2527188.1"
                     /translation="MNGAQWVVHALRAQGVNTVFGYPGGAIMPVYDALYDGGVEHLLC
                     RHEQGAAMAAIGYARATGKTGVCIATSGPGATNLITGLADALLDSIPVVAITGQVSAP
                     FIGTDAFQEVDVLGLSLACTKHSFLVQSLEELPRIMAEAFDVACSGRPGPVLVDIPKD
                     IQLASGDLEPWFTTVENEVTFPHAEVEQARQMLAKAQKPMLYVGGGVGMAQAVPALRE
                     FLAATKMPATCTLKGLGAVEADYPYYLGMLGMHGTKAANFAVQECDLLIAVGARFDDR
                     VTGKLNTFAPHASVIHMDIDPAEMNKLRQAHVALQGDLNALLPALQQPLNINDWQQHC
                     AQLRDEHSWRYDHPGDAIYAPLLLKQLSDRKPADCVVTTDVGQHQMWAAQHIAHTRPE
                     NFITSSGLGTMGFGLPAAVGAQVARPNDTVVCISGDGSFMMNVQELGTVKRKQLPLKI
                     VLLDNQRLGMVRQWQQLFFQERYSETTLTDNPDFLMLASAFGIHGQHITRKDQVEAAL
                     DTMLNSDGPYLLHVSIDELENVWPLVPPGASNSEMLEKLS"
     gene            complement(35685..35735)
                     /locus_tag="RN951_002195"
     CDS             complement(35685..35735)
                     /locus_tag="RN951_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527189.1"
                     /translation="MNNSTKFCFSRFRTGN"
     gene            complement(35822..35920)
                     /gene="ilvL"
                     /locus_tag="RN951_002196"
     CDS             complement(35822..35920)
                     /gene="ilvL"
                     /locus_tag="RN951_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ilv operon leader peptide"
                     /protein_id="HDX2527190.1"
                     /translation="MTALLRVISLVVISVVVIIIPPCGAALGRGKA"
     gene            36273..37793
                     /locus_tag="RN951_002197"
     CDS             36273..37793
                     /locus_tag="RN951_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418214.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HDX2527191.1"
                     /translation="MSLSIVHTRAALGVNAPPITVEVHISKGLPGLTMVGLPETTVKE
                     ARDRVRSAIINSGYEYPAKKITINLAPADLPKEGGRYDLPIAIALLAASEQLTANKLD
                     EYELVGELALTGALRGVPGAISSATEAIKSGRKIIVAKDNEDEVGLINGEGCLIADHL
                     QAVCAFLEGKHALERPKPTDAVSRALQHDLSDVIGQEQGKRGLEITAAGGHNLLLIGP
                     PGTGKTMLASRINGLLPDLSNEEALESAAILSLVNAESVQKQWRQRPFRSPHHSASLT
                     AMVGGGAIPGPGEISLAHNGVLFLDELPEFERRTLDALREPIESGQIHLSRTRAKITY
                     PARFQLVAAMNPSPTGHYQGNHNRCTPEQTLRYLNRLSGPFLDRFDLSLEIPLPPPGI
                     LSKTVVPGESSATVKQRVMAARERQFKRQNKLNAWLDSPEIRQFCKLESEDAMWLEGT
                     LIHLGLSIRAWQRLLKVARTIADIDQSDIITRQHLQEAVSYRAIDRLLIHLQKLLT"
     gene            complement(37818..38156)
                     /gene="maoP"
                     /locus_tag="RN951_002198"
     CDS             complement(37818..38156)
                     /gene="maoP"
                     /locus_tag="RN951_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ori organization protein MaoP"
                     /protein_id="HDX2527192.1"
                     /translation="MAESFTTTNRYFDNKHYPRGFSRHGDFTIKEAQLLERHGYAFNE
                     LDLGKREPVTEEEKLFVAVCRGEREPVTEAERVWSKYMTRIKRPKRFHTLSGGKPQVE
                     GAEDYTDSDD"
     gene            38275..39114
                     /gene="hdfR"
                     /locus_tag="RN951_002199"
     CDS             38275..39114
                     /gene="hdfR"
                     /locus_tag="RN951_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator HdfR"
                     /protein_id="HDX2527193.1"
                     /translation="MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLG
                     VNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARKEVAHTSRHNEFSIGASASLWEC
                     MLNQWLGRLYQNQDAHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQL
                     LGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQ
                     IAMLNGCTWLPVSWARKKGGLHTVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLD
                     EVY"
     gene            complement(39210..39285)
                     /locus_tag="RN951_002200"
     tRNA            complement(39210..39285)
                     /locus_tag="RN951_002200"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(39250..39252),aa:Trp,seq:cca)
     gene            complement(39294..39370)
                     /locus_tag="RN951_002201"
     tRNA            complement(39294..39370)
                     /locus_tag="RN951_002201"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(39334..39336),aa:Asp,seq:gtc)
BASE COUNT         9656 a        10746 c         9942 g         9072 t
ORIGIN      
        1 actaaaaaca gcatcaataa tcaacgcgat ataataaacc tgccttacat atcaactgcg
       61 ccagaggtag gattgaaaac gctctcctga ttttccaatt cattttctgg ataaataaat
      121 aatttatttt tgtcactatt atttatgtaa tcatcctgtc agggagaggg atctcaatta
      181 tcaatgctta attacgtcat cattttgatg acatgaaacc ggagcatttt gcatggaatt
      241 ttcgttttca cccaaacgtc ttgttgttgc tgtcgccgcc gctcttcctc tcatggccag
      301 cgcagcagat accccgtcaa ctgccaccgc acgcaaaggc tttgccggat acgatcaccc
      361 aaaccagtat ctggttaaac cggcgaccac tattgccgac aatatgatgc cagtaatgca
      421 gcatccggcg caggataaag aaacccagca gaagctggca gaacttgaga aaaaaaccgg
      481 taagaaaccg aatgtggttg ttttcttgct ggacgatgtg ggctggatgg acgtcggttt
      541 taacggtggc ggcgtggcgg tgggtaaccc tacaccagat atcgacgccg ttgccagcca
      601 ggggctgatt ttaacttcgg cgtattctca accaagctct tccccaaccc gcgccaccat
      661 tctcaccgga caatactcca tccaccacgg cattctgatg ccgccaatgt acgggcaacc
      721 gggcgggctg caagggttaa ccacgctgcc gcagttgctg cacgatcagg gctacgtcac
      781 tcaggccatc ggaaaatggc atatggggga aaacaaagag tcgcagccgc agaacgttgg
      841 ctttgatgat ttccgtggct ttaactcggt gtctgatatg tacaccgaat ggcgcgacgt
      901 tcacgtcaat ccggaagtgg ccctgagtcc ggaccgttct gaatacatca agcaattacc
      961 gttcagcaaa gatgacgttc atgcggtgcg cggcggcgaa caacaggcca ttgccgacat
     1021 tacgccgaaa tatatggaag atctggatca acgctggatg gactatggcg ttaagttcct
     1081 cgacaagatg gcgaagagcg ataaaccatt cttcctctac tacggcactc gtggctgcca
     1141 cttcgataac tacccaaatg cgaaatatgc gggtagctct ccggcacgca cctcgtatgg
     1201 cgactgcatg gtggagatga acgatgtgtt cgctaatctg tataaaacac tggagaaaaa
     1261 cggtcagctt gataacacgc tgatcgtctt tacctccgat aacggaccgg aagccgaagt
     1321 accgccgcac ggacgcaccc cgttccgtgg tgcgaaaggt tcgacctggg aaggcggcgt
     1381 tcgcgtaccg actttcgttt actggaaagg gatgatccaa ccgcgtaaat ctgacggtat
     1441 tgtcgatctg gcagatctct tccctaccgc gctggatctg gcagggcatc ctggagcgaa
     1501 agtggcgaat ttagtgccga aaaccacctt tatcgatggt gtggaccaga catccttctt
     1561 cctgggaaca aatggtcagt ctaaccgtaa ggccgagcac tacttcctca acggtaaact
     1621 cgctgctgtg cgtatggatg agttcaagta tcacgtcctg attcagcaac cttacgctta
     1681 tacccagagc ggatatcagg gtggattcac cggcacagta atgcaaacgg cgggatcgtc
     1741 ggtgtttaac ctctacaccg atccgcagga aagcgactcc atcggcgtgc gccatattcc
     1801 gatgggtgta ccgctacaga ccgaaatgca cgcgtatatg gagatcctga aaaaatatcc
     1861 accacgcgcg cagattaaat ctgactaagc cggcgctatc gctgagatct gcctttgccg
     1921 gatgcgatgc tgacgcatct tatccagcct acagaacgct gcaatttatt gaatttgcac
     1981 gatcatgtag gccggataag gcgtttacgc cgcatccggc aatcaaccgc aggcggccgc
     2041 cgatttctac ttactcacca ccagcaaatg cgcatgcata atgtcgctgg ccgggcgacc
     2101 gtgcgccagc aaatcagcca ttgctttaag atatggcggt agatggcgga aataacgctg
     2161 atacccggca cacaaataat tcagtcccgg tttgccgctg gcatcgagca tgaagcggtg
     2221 tttcgggcag cctccccagc acgcttttaa cacgttacaa ctgcgacact gcgccggtaa
     2281 ctgcttaaat ttatcttcac caaacgcctg ctgttgcggg gaatcgatca tttctgcaat
     2341 tgtttgctgg tgcatattcc ccagccgata ttgcggataa acatagtgat cacaggcgta
     2401 aacgtcgccg ttgtgctcaa caatcaccga gcgcccacag gttggctgat gatggcaaac
     2461 cgcacccggc gcaccgacaa aattggcaaa cgcccattcg atattcatca cgaaaatctt
     2521 gccgacgtcg cgtttgatcc agtggtcgaa tatcgccacc agaaactcac cgaactcctc
     2581 ggggcgcacc gaccattccg ttagctcacc ctgaatatca ccaggcgcat gtaacttaag
     2641 tccatcgcgg gcagttgttt catcagccag gcgctcgacc accggaataa actggatgaa
     2701 ttcgactccc gcatcgcaca aaaaatcata tacctgcaac ggttgctgcg cgctggtgcg
     2761 attaacgcag accagcacgt tatagtcgac atgatgtttt tgcaggagcg tcagggcacg
     2821 catcaccagc ttatgcgtgg gtctgccacc tttagtcacg cgatattgat tgtggatctc
     2881 aggcgggcca tccagcgata aaccaacaag aaaatgatgc tccgcgagaa acgcgcacca
     2941 ttcgtcatcc agcagcacgc cgttagtctg gaagctgtta cttatcttcc tgccagcacc
     3001 atatttcgcc tgtagcgcta cggcacggcg gtaaaacgcc agcccgagta gcgttggttc
     3061 gccgccctgc caggtaaaag ccacttcgtt ttgcggttcg ctggcagcga tatagtgacg
     3121 gacatacgct tccagcgtgt catcgtccat atgcgtgact ggcttttcgc ggtaaaggga
     3181 ttgtttttcg agataaaaac agtagtcaca gttcagatta caatcggaac cgctcggttt
     3241 cgccatcaca tgaaaagcac gcgttggaac ctgttgcagc atggtcgctc cttgcctgaa
     3301 gtcatccttc aatacgttaa gggcgaaatc ataccgtggg gcaatgagtt attacgggcg
     3361 tttattgcga agggagggtg acgaaatgca cagaaaacaa aaaaccccgc cgaagcgggg
     3421 ttcaaaattg gtcggcgaga gaggattcga acctccgacc cactggtccc aaaccagttg
     3481 cgctaccaag ctgcgctact cgccgaaata ctgctttttg aatttttagt tcaattcttt
     3541 aaagtcgtgg tgcgaggggg gggacttgaa cccccacgtc cgtaaggaca ctaacacctg
     3601 aagctagcgc gtctaccaat tccgccacct tcgcattgtc acaacttcta ataatggggt
     3661 ggctaatggg attcgaaccc acgacaactg gaatcacaat ccagggctct accaactgag
     3721 ctatagccac cactacaaat cttgttacgc ggtattacta ccaccgcagc tcaagcgccg
     3781 ggactaaatg gcgcgcccga caggattcga acctgagacc tctgcctccg gagggcagcg
     3841 ctctatccag ctgagctacg ggcgcttagc gccgttgcgg gggtggataa tacggacttc
     3901 ccacccctct gtctagtccc tttttaaata aattgcgcgt ttggttacgg tttgtgcgtt
     3961 ttgctgctta ttcctccagt ttatgcgctt tcccgtggcg attaaggcca aaaactttat
     4021 aaatcgccgt caccgccagc ataaagatga tgccaacaaa cagcgacata cgcgtatctt
     4081 cattaaagta catgccgatc aaaacgcaaa tcaggaatgc cattgttacg taattggccc
     4141 acgggaacag gattgagcgg aacggatggc tggcaatcgc cgctttatgt gcacgccgaa
     4201 aacgcagctg gcttatcaat atcacaaacc atggcaccat ccccggaagc acgctggcac
     4261 tgtagacgta gacaaacaca cgctgcggat tgggaatgat gtagttcagg catgagccaa
     4321 ttagcagaat agcaatagat actgccacac ccgcaaccgg tacgccgtga cgggaaactt
     4381 tcgccattgc cgccggtaac tgacggtttt tcgccagtgc gtagagcata cgtccgcaac
     4441 tgtacatgcc gctgttacag ccagagagcg cagccgtcag caccacaaag ttgataatgc
     4501 ccgccgctgc ggtaataccg attttggcaa aagtcagtac gaacgggctg ccgttgctgc
     4561 ctatttcatt ccacgggaag atggtgacga taacgaaaat cgcgcctacg tagaaaatca
     4621 ggatccgcca cagcaccttg cctacggcac tgcgcagcgt cacctgcgga ttcttcgctt
     4681 caccggcagt aatgccaatc agctccacgc cctggtagga cgccaccaca atacacagag
     4741 cggtcaggaa ccctttccag ccacccgcaa agaaaccgcc atgctctgtg agattgctaa
     4801 aaccaatcga ctgcccgcca ttgccaaagc caaagaaaat cacgcccagg ccaatgacaa
     4861 tcatcacgat aatcgtggtg actttgatca tcgcgaacca gaactcgatt tcgccgtaca
     4921 accgcaccgc cgccagattc gccaacgcca ccagcgccac tgcgatcaat gcgggtatcc
     4981 actgcgccat ctccgggaac cagaactgga cataaacgcc aatggcggtg atttcagaga
     5041 tccccaccgc catccacata aaccagtaag accaggcggt gagatagcca aagaacgggc
     5101 tcatataacg atgcgcataa acggcgaacg aaccggtaac cggttcgagg aacaacattt
     5161 cgcccattga acgcatgatg aaaaagacga acagcccggc gatgatatag gccaacaata
     5221 cggatggccc ggcccatttc agggtactgg cggcccccat aaacaggccg acgccaatgg
     5281 tgccccccag ggcgatgagt tcgatatgtc gagcttccag cccacgctgt agctctggtt
     5341 tgttatctgc cataaatcct cgtgttgtgt ttgcatgctt tccggtgtta ccggttatcg
     5401 ttatgggtac atcgagtgtt gcaaatgttt tcgtaattca ggagaaatgg caaataaagc
     5461 attaaaaatt tgaatgcttt gtgtaataaa aaagcagaca ggcgacggag tgaccactcc
     5521 gtcgctttac aaagagagga aaatcatagg ttgccggtgt agtgccagcg taaataacgc
     5581 agcaaacgaa gctgacgctt aatgcggctc ggctgcgaaa gcaggcggta gagccactcc
     5641 agccccagcg tttgccagat tttcggtgcg cgttttacgt gaccggtgaa aacatcgtaa
     5701 gtcccgccaa cgcccatata cagcgcatct ggatgtacca gacggcagtc gcgcatgatg
     5761 atctcctgct ttggcgatcc catcgcaacg gtgacgattt gcgcaccgct ggcatgaatg
     5821 cgttcaaaca gcgcctgacg ctgctcgggt ttaaaataac catcctgact gccaacgata
     5881 ttcacattcc actggttgcg cagtttagct tcagtttgcg ccagcacttc aggtttaccg
     5941 cccacaagaa ataccggcgt cccttctttg cctgcgcgcg ccatcagctc ttcccagaga
     6001 tcggcaccgg caacgcggga aacctgcgcc tgcgggtact ttttacgtac tgaacgtaca
     6061 acgctgatgc catccgcata tttaaattcg gcagcgttaa ttaactccct gacctcggcg
     6121 ttatcttcaa tagtcagcat tttttcagca ttaatggcaa ccagcgttcc ctgcttaagc
     6181 tgcccgtcag caaacagata atcgagggcg tgctgcatat cacgccaacc aatcaactgt
     6241 aagccacgca gcgtataggt tggtgccgtg gtgttgttat tcattgttat ccttcaacct
     6301 gcgtccggag cgatgatttt gtacgtttat gaatgagtcc ggcgctttca aaaagccagt
     6361 acaacagttt tgcgatcatc agacatgcgc cgaagaccac gataaaaaag accacgcgtg
     6421 agacaaacga atccagccct tcacgcgcca gcacgatcat attgaagatc gccccaaagc
     6481 agaaactgtg caatatcgca gctttatagc gattaggctc gcggttgccc agctcataca
     6541 gccagtcgaa ccatttgatg atcagaccaa ccacgatcgc cccgagcggg atgaacaacg
     6601 cgccgcccat caccaccagt gagcctataa gcgtaggcga gatcgccagt ccggagtggt
     6661 tattcagcac ttcccaggta aagtagttgg ctgagttcag caccatactc gggcgacccg
     6721 gccacagcca ggaagggata aagacataga aatcgcggac aattggagcc aggccctgga
     6781 agtcgatgtt gtcgtagttc tgcaacagca acgccagatt ctcccacggc gagaaggtgt
     6841 cgcgagtgag atagagaaac gtatagaacg cttcatcgcc gctcacattc attccatagc
     6901 gttttagtgc cagccagaac atgccaacaa tccccagcac gcccgccgcc gccagcatcc
     6961 acaacgaaat ccagccgcga ataatgccaa taaacaggaa gatagcgaat gcgatgatga
     7021 tattggcgcg agtgccgccg acaatcatat aagtcagcaa gccaaaggcg accgtgctga
     7081 cgaggaaaaa cagccacgct ttgctgtcct ggcgcagaaa gtagaccacc agcatcgccg
     7141 ggatgaaaaa gtaaaagaag cgttttaacg ccacgccgga gacttcactg gaaaagatct
     7201 gactgtagga gttaagccgg aacagcaaaa agccgttgtg catgaagaag atgccgacgc
     7261 ttaccagcgc gatacccatc aggatcaccc acgtaagatt ggtctccacg cggttcatgg
     7321 taaacagcgg acggcgcggt acatcagcaa cgcgtttgcg taggcgggtt ttgtaggtga
     7381 catagtaaac cgcgtagaag cagcccgcag aaagcaacgc ctgcaacaag atttctggcg
     7441 gcgcgacacc aacatcaaag cgaaatacca gcacgctggt cagcgggaag ccgaagaaaa
     7501 aggtgagcaa aaacagcaat gaaaagaaga cattgaagtt aaagcgcaca cggcgaaact
     7561 caaaccaggt cagcgtggca ataaacagcg tgcagagcag ccagacaaca aacaggccac
     7621 tgaattgcag cagactcatg cgacctcccc ggcggcaatc gccaacgccc gctgccagcc
     7681 ttgtagatag ttagggctaa agaaggcaat ggtgttttta tccaccgacg ccaactggcg
     7741 ctgcgcttca cgcacaatat cctcgttgag atcgtcggta gtaaacagca ccggcaaatg
     7801 ttgttccgtc atatcctgcc agaacggatt ttcccggtta agcacacaag gaatgcccgc
     7861 ctgaatcagt aagcacagcg taccaatgcc ctgctggcgg gcaaaaataa agtaaccaag
     7921 atcgcactga cgaagtagcg ccagataggc gtcaaattcc agtttttcgc tcagaatttg
     7981 tagattttct tcgctgaata actccagccc cgcctgacga acttcctcaa tgtacgcttc
     8041 gttattaggc ggatatccca tcggcaccac cacttttacc gtatcgccaa attgctgatg
     8101 aacggcgcgc aaggcagcaa tatgctcatt gctgcggtcg ccggagttcc ccaccagaat
     8161 ggtcattttc ccttcacgtt gccgatcgtt cgccatcgta ttgagcgaag ggtccatccg
     8221 cgtcgggaag aacagcagtt cgccccgcac ctttgggtgc gttttggcaa aaaagctcaa
     8281 atcgccgcgg gtggcaaata cacagccgac tcgcttttgc gccaggcgac gtagtgggta
     8341 aaaaagctta tatctcaagc cactggaaag ctcatacagg tctgcccccc agatatgcca
     8401 gaaaaactgg ctgggcttaa tgccaccact cagcagagcc agccacagtg tgggattgaa
     8461 ctgaccgtgg aagaaaaaac gctgctgacg gttagctttt gctttcgcga tgaccgcttc
     8521 cgccagcgat tttttcccag ggaaaaattg cacagaaagc gccggacagc tatcacttaa
     8581 gccgtcgtcc ttgccaacaa ccataaactc gcgcgcgtgc tcgctcgtcg cggccagcgc
     8641 gtcattgaaa aaccgcaaaa cggttcggtt atggtgaggg atatccgatc ccagtacgtg
     8701 aatcagtaca gtcatgcccg cctacgccag agtaaaaaca cgccacaaca aagagaaaaa
     8761 tagacgatat aagttgccat atatgcctgc gccgcgccca gtgcaccatg cgcagggatt
     8821 agccagtggg caaataccat caataaagtg aactggctga cttccgccag aatataaaac
     8881 cgcagtgacg ctttggcgat caccagataa ccaaagacat aagcgcccac ttttaacaca
     8941 tcacccacta actgccaggc aaagagatcg cgcatagcgg taaatttatt cgacaacagc
     9001 agccagatag caaaatcacg cagcagccag acggtaaaac tcgccgccgc cactgccggt
     9061 aagacgaatt tcagcgattt aaccacttcc cgggtgatat cgcgcttttc cgttagccgc
     9121 gacaacgtgg gcagcaaata tacgctgaac gatgccgtaa taaattgcag gtaggcatcg
     9181 gaaatactgc tcaccccttg ccagatcccc acctcatccc agctatactg cgccgccagc
     9241 agtttacgca tcatgatgta agcaacaggc aaggtcaccg acgtaatcaa cgccatgagc
     9301 gtaaatttgc tcaactgccc tgccagaccg ttatcccagc tgggtttcag atagcttaac
     9361 gggatgacac cacgtttgat caacatgatg gcggcaggaa ttaccaccag cgcgggaatc
     9421 agcgccagac ccagcaacgc cccttcataa ccgcccaaac ggtaactgac gtagtacgcg
     9481 agaacgccaa tcaagctgcc gacaatcagc gataacgcat tacctgcggc atcgcgaaag
     9541 cctttcatca gcgccagtaa caggttgccc caggcgatcc ccatttgcac cagcgccact
     9601 aaacgcacca gcccctgata gtcggtatta ccaaacaatc cctggctgat tggcgcagct
     9661 gccagcacaa aaaccagcgc catcagcgta gagaaaccaa gtaccatcgc tgatgaagtg
     9721 ccgaccacgc ggcgcagctg ttgcggatta tcatggtact gggcaacgta tttggttaca
     9781 ccgttaaaga tgccagcccc ggcaagcacg ccgagcacgg taatcaactg gcggaaattt
     9841 gccgccagcc caagccccgc cggaccaaat gacaccgcca gcaacttacc gaccagtaac
     9901 ccggcaccaa tcttgaccag tgtactggcc gccgtccaca aggacgcttt tgccaacgac
     9961 atatcaggaa aagtagttca acaaagtcgc aattaccgta cgctgattga cgggcgacag
    10021 gttgtagaac agcggcaggc gcagcaggcg ctcgctctct ttggtggtgt agcgatcttc
    10081 accgtggaac tcaccaaagt gttcccccgc agggcaaccg tgcagcggaa tgtaatgaaa
    10141 caccgccatg atttccgctt ctttcagaaa gttaatcaac gcgctccggt catcaatatc
    10201 ccgcagttta atgtagaaca tatgcgcgtt ctgcacgcag ccatcgggaa tcgacggcag
    10261 ctcgatacgc ccggctttcg ccagaggcgc taacgcatcg tagtagtttt gccacagcgc
    10321 cagacgttgc tggttgatac gatccgctgc ttccagttgc gcccacaggt atgcagcttg
    10381 cagatcggac atcaaatagc tggagccaat atcgcgccag gtatatttat cgacctgacc
    10441 acggaagaac tggctgcggt tagtgccctt ttcacggatg atctcggctc gttcgattaa
    10501 cgctttatcg ttaatcagcg tcgcgccgcc ttcaccgccc gccgtgtagt ttttggtttc
    10561 atggaagcta aagcagccaa tatgaccaat ggttcccagt gcacgccctt tgtaagtgga
    10621 catcacgccc tgagcggcat cttctaccac aaacaaatta tgctttttcg ccaacgccat
    10681 aatggtgtcc atttcgcagg ccacacccgc gtaatggacc ggcacgataa cgcgcgtttt
    10741 gtcggtgatc gccgcttcaa tcagcgtttc gtcgatgttc atggtgtccg ggcgaacatc
    10801 cacaaaaacg atttttgcgc cacgcagcac aaaggcattg gcggtggaga caaaggtgta
    10861 gctcggcatg atcacttcat cgccaggctg gatatcgagc agcagcgccg ccatctccag
    10921 cgaagcggtg caggacggcg tcagtaacac tttggcgctg ccaaaacgtt gctccagcca
    10981 ctgctggcag cgacgggtaa aaccgccatc gccacacagt ttgccgctac ccattgccga
    11041 ctgcatatag tcgagttcgg ttcccaccac cggcggtgcg ttaaatggaa tcatgtgatc
    11101 acctgtataa ccagtacgcg gtgctttcta cattcgcacc actttgtatg tatcgtttaa
    11161 gcgcggcggt gttgcccatt tgggtcgcca cccgcaaagt tgttttaccg cgagcatacg
    11221 cccagtttag cgccgtttgc atcagctcag cacctgcacc gcgtccagcc agcaggccaa
    11281 ttcgcgcatc tgtcgcattg agttcccgta aagagacata gccgcgaata tcgccggacg
    11341 ccgcacgtaa aatcagacat tgatgatcaa aggtgccgcg cacggcattt tcaatccact
    11401 gtgcataaaa gcgactgctg gcgtcaggcg cataccacgg cgcacgaaaa cggctttgcg
    11461 caaatgcggc gctggctaac tgacgtaatg cgggaatatc ggtctcttgt gccactacag
    11521 caccgctatc actggcattg ttcacgggta gcgccaaatc aacttcacct tctaccaggg
    11581 agaatcccag ctgttgcagg gcatccagtt cacccgtatt tgatgccgca attttggcct
    11641 gcacccgtga ccacggcgct aacgcgtctg gcgtcaggag cggtgcttca gacgtaatgc
    11701 gcacgatggc gctgttaaca ccaaagaagg cgttttccca ggttagtggc tcaatactgg
    11761 cgcggacggg cacgaagtaa ctccagcaga tattggccgt agccagtttt cgctaatgaa
    11821 ctggcagcac gcttcacacc ctcgtcatcg agccagccgt tacgccaggc aatctcttcc
    11881 aggcaggcaa tcttaaagcc ctggcgtttt tccaccgtct gtacaaaggt gctggcttca
    11941 atcaggctgt cgtgagtgcc ggtatccagc caggcaaatc cgcgcccgag cagttcaacg
    12001 gtcaggttgc ccgcctcgag gtacatctgg ttgatggagg taatctccag ttcaccacgc
    12061 tccgacggct tcacctgctt tgcgtactcc acgactttac tgtcgtagaa ataaagcccg
    12121 gtcaccgccc agtttgactt cggctgtttt ggcttttctt ccagcgagat agcgcggaaa
    12181 ttgtcgtcaa actccaccac gccaaagcgt tccgggtcca tcacctgata gccaaaaacc
    12241 gtcgcccctt cggtgcgcgc cgcaacatga cgcagcttcg gactgaagcc ctgaccgaag
    12301 aagatgttat cgcccagcac cagacaagaa ggttcaccat taaggaaggt ttcaccgatg
    12361 ataaaggcct gcgccagacc gtccgggctg ggctgttcgg catattccag ctggataccg
    12421 aactcactac catcgcccag caggcgctgg aaataacctt tatcttccgg cgtagtgatg
    12481 atgagaattt cgcggatacc ggccagcatc agcaccgaca gcggatagta aatcattggc
    12541 ttatcgtaaa tcggcaacag ttgcttcgat acgccgcgcg taatcggatg caatcgggtg
    12601 ccggaaccgc ccgccaggat aatacctttc atgtttgcct ccgctgaaaa ttagcctttc
    12661 agacctaaac gctcgccctg atagctgccg tcctgcacct gcttccacca gctttcatta
    12721 gccagatacc actgaaccgt tttacgcatt ccactttcaa aggtttcctg cggcagccag
    12781 ccaagttcac gggcaatttt cgaagcatca atggcataac gcagatcatg ccccggacgg
    12841 tcagcgacaa aggtgatcag gtcacgatag tgcgccacgc cgtgcggctt gttcggagcc
    12901 agttcttcca gcagctcgca aatggtttcc acaacatcga gattcttacg ctcgttgtga
    12961 ccaccaatat tataggtttc accgactttc ccggtggtcg ccacgcaata cagcgcgcgg
    13021 gcgtgatctt ccacatacag ccagtcacgg atttgctgcc cgttgccata taccggcagc
    13081 gatttacccg ccagcgcgtt gaggatcatc agcgggatca gtttttccgg aaagtggtaa
    13141 gggccgtagt tattcgagca gttggtgata agcgtcggca gaccataggt ccgcagccag
    13201 gcgcgcacca gatggtcgct gctggctttt gacgcggaat aagggctgct cggcgcatac
    13261 ggcgtggttt cggtgaagaa atcatccgtc gagtgcaggt caccatatac ttcgtcagtg
    13321 gagatatgat gaaaacggaa cgctgatttt ttatcttccg tcagcgcatt ccagtaagcc
    13381 cgcgccgctt caagcaatgt ataagtcccg acaatgttgg tttcaataaa cgctgccggg
    13441 ccgtcaatag aacggtcaac atggctttcg gctgccagat gcatgacaca gtctggctga
    13501 tgctcagtga atacgcgtgc cagttctgcc cgatcgcaga tatcaacttt ctcaaaggca
    13561 aagcgctcgc tttgcgcgac cggtgccagc gacatcaggt ttccggcgta ggtcagctta
    13621 tcgaccacta ccaccgcgtc gctcgtttcg ttgatgatat aacgcaccag cgccgagcca
    13681 ataaacccgg caccacctgt tatcagaatt tttctcatca gcgccagact cctttggcat
    13741 cgacgacata ctgctgatgg acattgtcgc cattgataac tttgaactga ctatgatcga
    13801 ccagcatcac cagcacgtct gccgttgcca gcgcctcgtc aagctgcgcc agagtacaaa
    13861 gcccggtcag ttttttcggc aactggtgga tgttaggctc aacaaccaga gtttcgccgc
    13921 tatgccactg ggcgatcagt tcagcgattt ccatcgccgg gctttcgcgc aggtcatcaa
    13981 tattcggttt aaacgccaga ccaaagcagg cgattttcag ttcactggcg cgtttatcgg
    14041 tagccgccag gcaatcagcc accgccgctt tcacctgatc gataacccag aacggtttgt
    14101 gatcgttcac ttcgcgcgcg gtacggataa gccgcgcctg ctgggggttc tgtgccacga
    14161 taaaccacgg atcaacagca atgcagtgac cgcccacgcc agggccaggc tgaagaatat
    14221 taacgcgagg gtgacgattc gccaggcgaa tcagttccca gacgttaatc ccctgatcgg
    14281 cacaaatcag cgacaattca ttagcaaaag cgatattcac atcgcggaag ctgttttcgg
    14341 tgagcttaca catttccgcc gtccgcgagt tagtgacgac acactcacct tcgaggaaaa
    14401 ttttgtacag ttcgctggcg cgggccgaac aaaccggcgt cataccacca atcacgcgat
    14461 cgtttttaat cagctcgacc attacctgtc ctggtaacac gcgttccggg cagtaagcaa
    14521 tgttgacgtc cgcctgctcg cccacctgct gcgggaaagt gagatccgga cgcatctctg
    14581 ctaaccattc tgccatcttc tcggttgacc ccaccggcga ggtggattca aggatcacca
    14641 gcgcgccttt tttcagcact ggcgcaatgg agcgagcagc cgattcaacg taggtcatat
    14701 ctggctcatg atcgccctta aacggcgtgg gtacagcaat cagccaggca tccgcttcaa
    14761 ctggcgtcgt gctcgctcgt aaaaaaccgc cttctacggc agtttttact acactcgcca
    14821 aatcaggttc gacgatatgg atttcgccac gattgatggt atcaaccgca tgttggttga
    14881 tatcgacacc aattacctgt ttttgccgtg aggcaaacgc tgctgccgtt ggcagcccga
    14941 tataacccag tccgataaca gaaatggtcg caaaactcat agtgatatcc gattattttt
    15001 taacgcttcc agaatgcgag agcatgcctg accatcacca tacgggttat gggcgcggct
    15061 catagcttga tattcgtttt cgtcttttaa aagacgcgtc acttcctcga caattcgctg
    15121 cttatccgtg cctaccagac gcaccgtacc cgccgtcacc gcttccggac gctcagtggt
    15181 atcgcgcatc accagcacag gtttccccag cgaaggcgct tcttcctgaa tgccgcctga
    15241 gtcggtcaaa atcagccagg cgtggttcat cagccagaca aacggtaaat actcctgggg
    15301 atcgatcaga atgacatttt tcacatgccc cagaatgcga ttgaccggct ctctgacgtt
    15361 cgggttgaga tgcaccggat agacaatctg gatgtcctgg tgcgtggtgg cgatgtctgc
    15421 cagcgcgtgg cagatttctt caaagccacg accgaaactc tcacgcctgt gaccggtcac
    15481 cagaatcatc tttttatcgg ggtcgataaa cgggtaattt gccgccagtt ctgaacgcag
    15541 cttgtcgctg ctcatcacct ggtcacgcac ccataacagt gcatcaatga ctgtattacc
    15601 ggtaatgaag attcggctat ccgcaacgtt ttcacgcagc aagttttgcc gggaagtttc
    15661 ggttggagag aagtgataca tcgccagatg cccggtcaat gtacggttag cctcttccgg
    15721 ccacggcgaa tagagatcgc ccgtgcgcag accagcctca acgtgaccaa caggaatacg
    15781 ctgataaaac gccgccaggc tggttgccag cgtcgtcgtc gtatcgccgt gaaccagcac
    15841 gacgtctggt ttgaactcgg caagaatagg ttttagccct tccagaatcc gacaggttat
    15901 ctctgtcagg ccctgtcctg gctgcattat gttgagatcg tagtcaggta caatggaaaa
    15961 gagtttcagc acctgatcga gcatctcccg atgctgcgca gtgacgcaaa ctttagcctc
    16021 aaaaaaagga tcttttgcca acgcatgcac caacggcgcc atcttgatgg cttccgggcg
    16081 cgtaccaaat acagtcagta ctttcacatc gattctcttc gaataagcgg cgagcgcctt
    16141 tgcgctcacc gcagcagtgt tgctatttcg agcaacggcg ggttaatgcg acaccagccc
    16201 cgatcagccc cccgacaatg ccccacataa tcatcaggaa ggcacgacgt gggctatcgc
    16261 gttttaccgg ttcttccggc gtacgcaaat agcgataggt ctgaaaacgc ggatccaggg
    16321 ttggaccaac attcagggtg tttaacatgg cccgattctg atcatagtcg agatcaaagg
    16381 ccggaccgac ggcctgtaaa ttttccagtc gagcctgaag cattggacgc ccaagcagga
    16441 acatttctga atcaggtaat tcctcggcag gtacatctgt cgcactgcgc gaaatattat
    16501 gctgctcagc aattttcagc gcctgctcaa tgctgttcat ccggcggtcg tagatggctt
    16561 tcgccacctc ttcctgacgc ttcacctgag ctttcatctg gatggtacgc gccgcccatg
    16621 cgcctttcag ctcatcattc agatggctgg ctgcacgctg gctggcaaaa gcaacatact
    16681 gacgtaacag gttattagcg tcaggcgcgg tttcggcaat aagcttcacg ctgtcattga
    16741 ccgcgcgggt aaagtctccg gggataaact ggatgttgtt aatcatttca tccagcaacg
    16801 ccgcatcggc tttgctgttg cccaccatcc gctgtttgta atagtcggtt tgcagccaga
    16861 actctctgcg ggtatcccac gaggccagtt gcataacaaa ctctttatag gcttcgtcca
    16921 tgaccgatgg ttggtcggca gaagccatgt ttgaacggac atccaggtta cgcaaaaatt
    16981 gctgctgcga gtaatatccc cccagcatat tcaccgttgg acgatcggta atcgccgtcg
    17041 agctccactc ctgacgagca aaaaacgtat acgccagcgc gattaacgca aacgccagcc
    17101 ccatgccaat aatccatagc ttcccagccc acaaggtacg aaacaaccca cgaatatcca
    17161 gttcattttc agcgtcttcg gccggtttcc caggcattgg ttgtgtcatc acatcctcat
    17221 ttatttggtt aaattggggc tgccaccacg atttctacgc agtctgcgtt ttacgcgctt
    17281 aataaagcga gcaactttcc aggcacgctt aatgcaatat ccatagagga agaatgctag
    17341 caaaaagagc accagcatga cccactccgg gacaaaatga gaatattctg ccagcacgcc
    17401 aatggaagcg agcagtgctg cggcaagggt aatcagcaca aacgcctgac gggaagtaaa
    17461 cccggcacgc atgatcaaat ggtgaatatg ctgacggtca ggagagaatg ggctcatgcc
    17521 tttacgcagg cgacggtaca taatcgccac catatccatt agcggaatgg cgattatcca
    17581 caaagcggta accgggctga tgggatgggt tttgccctgg gtcgtttcga gcaggatcca
    17641 gataacggta aaaccaatca gcgtactgcc cgcatcaccc ataaagactt tgtagcggcg
    17701 acccaggata ccaaggttaa gcatgatgta tggcaggatg gcggcgatca tcgcaaagca
    17761 ccagattgcg aggctggttt gcccgtcgaa ccacaaaatc ataccgattg ctgcaaacga
    17821 gacgcaggac aacccgccca gcaagccatc aatgccatca accatgttga acgcattaat
    17881 ggccgcccag acggcaaata gcgtcaggaa gtaaccaaac ggtccgagca ccatctccca
    17941 ggagccaaag atataaccca ggctactgag ataaagcttg ccgaacacca tcataacaat
    18001 gccaacagcg gcctgtatgg tggcacggat ttttacgctg atatcaaaac ggtcatccag
    18061 cgcgccaatg aaaacaagca caccggcaca agcgagatag agagatgcat gcggaatata
    18121 gtaatcgaca attccgaacg tgaagcaaat ccctgcgtaa accgaaatcc ccccaacgag
    18181 aggtatcaat ccctggtgac gtttgcggaa gtttggttta tccactaaac cgactttttt
    18241 tgccacctta cgggcaaaaa acagaaacag tgtcgtgaat aaaaaaatac tgatgagatc
    18301 agtactcact gccagtaaat tcacaatgca tgctctcaga gaaaattatt agcagaagta
    18361 taaccacgaa gacctttatt cagaagggaa agtccgttcc aaacccacca gtcctgtgca
    18421 aaaattaacc atttgatatg caaattgcat aacatgccag caaattccag gaattttcct
    18481 aacatcgcca gcgcggcatt aagattacag atataaaagc aaaacgccac gtaaacacgt
    18541 ggcgtttttg gcataagaca aatttatgag cgtttcatca tttcgaagaa atcgtcattg
    18601 gtcttggtca ttgccagttt attaatgagg aattccattg catcgatttc gcccatcggg
    18661 tgaatgattt tgcgcaggat ccacattttc tgcagttctt cctgagtcgt gagcagctct
    18721 tctttacggg taccagaacg gttgtagtcg atagccggga agacgcgttt ttcagcgatc
    18781 ttacgagaga ggtgcagttc catgttgcct gtacctttaa actcttcgta gataacttcg
    18841 tccattttag aaccggtatc gataagcgcc gtcgcgataa tggtcaggct gccgccctct
    18901 tccacgttac gcgccgcacc aaagaagcgt ttcggacgat gcagggcgtt ggcatccaca
    18961 ccaccggtca acactttacc tgacgccgga acaacggtgt tgtaagcgcg cgccagacga
    19021 gtgatggagt cgagcagaat gataacgtct ttcttgtgct caaccaggcg tttggccttc
    19081 tcgatcacca tttccgcaac ctgaacgtgg cgagatgcgg gttcgtcaaa ggtagaagca
    19141 acaacttcac cttttaccag acgctgcatc tcggttactt cttccggacg ttcgtcgatc
    19201 agcagaacca tcagcacaca atccgggtgg ttgtaagcaa tgctctgagc aatgttctgc
    19261 agcagcatgg ttttaccggc tttcggcggt gccacaatca gaccacgctg accacgaccg
    19321 ataggtgatg ccagatccag tacgcgagca gttaaatctt cagtagaacc gttaccacgt
    19381 tccatacgca gacgagagtt tgcgtgcagc ggggttaagt tctcaaagag gattttgttg
    19441 cgggcgtttt caggtttgtc gaagttaact tcgttaactt tcagcagcgc aaaatagcgt
    19501 tcaccttctt tcggcgggcg aatcttacca gagatggtat caccagtgcg gaggttgaaa
    19561 cggcggattt ggctagggga aacgtagatg tcatcaggac cggcgaggta ggagctgtct
    19621 gcggaacgga ggaaaccaaa tccatcctgc aatatctcca gtacgccatc accaaagata
    19681 tcttcgccac tctttgcgtg ctgcttcagg atggcaaaaa taatgtcctg cttacgcata
    19741 cgagccaggt tttccagccc catattttcg ccgagagtga tcagctcaga aaccggcgta
    19801 ttctttaatt cggtaagatt catagtggtg tgagttctta aacttggggt aaatctcgaa
    19861 cttaatgttg tgaatggtat ggcaggatca tccatgcctg tttacggtca tcgactcatg
    19921 tcttttcgct gcctggtcac aggagagtac gcagaactga aacgacaaga cggattgagt
    19981 gacgagccag aaatctgttc acttcgcatt taagataaaa cgggaagcgt tggaaattac
    20041 aagattcaaa cttaataagg tatgtttaat acgaagtcaa cactaagtta gcatgactca
    20101 cgccgggcgt ccagttttta gcgacggggc acccgaacat gaaattccct tacgccaggt
    20161 tagcgtcgag gaactctttc aactgacctt tagacagtgc acccactttg gttgccgcca
    20221 cttcaccgtt tttgaacagc agcagagtcg ggataccacg gatgccatat ttcggcgcag
    20281 tgccagggtt ttgatcgatg ttcagttttg caacggtcag tttgccctga tattcgtcag
    20341 cgatttcatc cagaatcggg gcgatcattt tgcacggacc gcaccactct gcccagaaat
    20401 cgacgaggat cgccccgtcc gctttgagta catccgtgtc aaaactgtcg tcagtcaggt
    20461 gaataatttt atcgctcata tataactcca caggaataag cctggcgtgt tggtttcgtt
    20521 gttggtgtaa cattaaccaa ctaaaggttg actttatttc accggatacg ctttcgtaaa
    20581 gcaatagtaa gctgatattc taccacacta tgagcaaaac acatttaaca gaacagaagt
    20641 tttccgactt cgccctgcat ccgaaggttg tagaagccct tgaaaaaaaa gggtttcata
    20701 actgtacgcc cattcaggca ctggcccttc cgctgacgct ggcgggtcgt gacgtagccg
    20761 ggcaggcgca aaccggtacc gggaaaacga tggcgtttct tacgtcaacg tttcattatc
    20821 ttctctctca tcctgcgatt gccgatcgca aggtgaatca gccgcgtgcc ttaattatgg
    20881 caccgacgcg tgaacttgcc gtgcagatcc atgccgacgc agaaccgctg gcggaagcta
    20941 ctggcctgaa gctgggtctg gcttacggtg gtgatggcta cgacaaacag ctgaaagtgc
    21001 tggaaagcgg cgttgacatt ctgattggca ccacggggcg tttaattgac tacgccaagc
    21061 agaaccacat taacctcggt gccattcagg tggtggtact ggacgaagcc gatcgcatgt
    21121 acgatctggg ctttattaaa gatatccgct ggctgttccg ccgtatgccg cctgcaaacc
    21181 agcgcctcaa catgctgttc tccgccacgc tttcgtaccg ggtacgtgaa ctggcgttcg
    21241 agcagatgaa caatgccgaa tatattgaag tggaaccgga acagaaaacg ggccaccgta
    21301 ttaaagaaga gcttttctac ccttctaacg aagaaaaaat gcgtttgctg caaacgctga
    21361 tcgaagaaga gtggccagac agagcgatta ttttcgccaa caccaaacac cgttgtgaag
    21421 agatctgggg ccacctggca gcagatggtc atcgtgtcgg tttattgaca ggcgatgtcg
    21481 cgcagaaaaa acgtctgcgt attcttgatg aatttacccg tggcgatctg gatattctgg
    21541 ttgccaccga cgttgccgcg cgtggtttgc atattccggc agtgacgcac gtctttaact
    21601 acgatttacc cgatgactgt gaagattacg ttcaccgtat tggtcgtaca ggtcgcgcag
    21661 gcgcaagcgg tcactctatc agcctggcgt gtgaagagta tgcattgaat ttgcctgcta
    21721 ttgagaccta tattggtcac tcaattccgg taagcaaata caatccggac gcattgatga
    21781 ccgatctgcc aaaaccgctg cgcctcacgc gcccgcgcac aggcaatggt ccgcgtcgta
    21841 ctggcgctcc gcgtaatcgt cgtcgttcag gttaaataaa aaatgtcata ctcaaaatca
    21901 ttcaaactgt atcaagatgg caagagaatg aatcccgatg agcttactgt agtaagtgat
    21961 tcaggtgaaa gaatgcagcc aacacagaga cagattgaag gatgaagagt atgggttcca
    22021 cctcgtcgct gtatgcagcc attgatctcg gttcgaatag ttttcatatg ctggttgtgc
    22081 gcgaggtggc tggaagcatc cagacgctga cgcgaataaa acgcaaagtg cgtctggctg
    22141 ctggcctgaa tagcgaaaat gccctctcca atgaagcaat ggagcgcggt tggcaatgtt
    22201 tgcgcctgtt tgctgaacgt ctgcaagata ttcctccctc gcaaattcgc gttgtcgcta
    22261 cggcgacgtt acgccttgcc gtcaatgcgg gtgattttat tgccaaagcg caggaaattc
    22321 tcggttgtcc ggtacaggtg atcagcggtg aagaggaagc acgtctgatt tatcagggcg
    22381 ttgctcacac cactggtggt gccgatcagc gcctggtggt ggatataggc ggagccagta
    22441 ctgaactggt aaccggcacg ggtgcacaaa ccacctcgtt gttcagcctg tcgatgggct
    22501 gcgtcacctg gctggaacgc tattttgccg atcgtaatct ggggcaggaa aattttgatg
    22561 ctgcagaaaa agcggcacgc gaagtgttac gtccggttgc cgatgaatta cggtatcacg
    22621 gctggaaagt gtgcgttggt gcttccggca ccgtgcaggc gttacaggaa atcatgatgg
    22681 cacaggggat ggatgaacgc attaccctgg aaaagttgca gcaattgaaa cagcgagcca
    22741 ttcattgcgg tcggctggag gaactggaga ttgacgggct gacgctggaa cgtgcgttag
    22801 tgttcccgag tggtctggcg atcctgatcg ccatttttac cgaactgaat attcagtgta
    22861 tgaccctggc gggcggtgcg ctgcgtgaag gcctggtcta cggcatgttg catctggccg
    22921 tcgagcagga tattcgcagc cgtacgctgc gtaatattca acgccgcttt atgatcgata
    22981 ttgatcaggc acagcgcgta gccaaagttg cggctaactt cttcgatcag gtggaaaacg
    23041 aatggcatct tgaagcaata agccgcgatt tgctcatcag cgcctgtcag cttcatgaaa
    23101 tcggcctgag cgttgacttc aaacaagcgc cgcaacacgc tgcttatctg gtgcgtaatc
    23161 tggatcttcc cggttttacc cccgcacaga aaaaattgct ggcgacgcta ctgctcaacc
    23221 agactaatcc ggtcgatctc tcatcgctgc atcagcaaaa tgccgtaccg ccgcgcgtcg
    23281 cagaacaact ctgccgttta ctacgcctgg ccatcatttt tgccagccgt cgccgtgacg
    23341 atctcgtgcc agagatgaca ttacaggcta accatgaact gttgaccttg acgcttccgc
    23401 aaggttggct aacccaacat ccgctgggta aagagattat tgctcaggaa agccagtggc
    23461 agagctatgt ccactggccg ctggaagtgc attaatgagt aagtgccgga tgcgatgctg
    23521 acgcatcttt tccggccttg attatttccc tcgttttgcc gccatcatcg ctttcagatt
    23581 cgccagatgg ctttgccctt tctgcatccg ttcttcggcg ctgaccactt tgcgctcctg
    23641 ttcccaaatc agatcatcct gcggcagctc cagcaaaaag cggctcggct ccgggcgcac
    23701 cagttcgccg tactgacggc gttctttaca cagcgtaaag gtcaattcct tctgggcgcg
    23761 ggtaatgccg acataggcca gccgccgctc ctcatcgata ttatcttcat cgatgctgct
    23821 ctggtgcggc aaaaaccctt cttccatacc gaccatgtag acataaggaa actccagccc
    23881 tttcgacgcg tggagagtca tcagttgcac ctgatccagc tcttcttcac tctcaccacg
    23941 ctccatcatg tcgcgcaaag taaagcgcgt caccacctgg gtgagcgtca tcggctcatc
    24001 cagttcactg ccttccagca tctccgtcat ccagctaaac agttggttga cgttcttcat
    24061 gcgcatttcg gcggctttcg ggctgggcga tgtttcgtac agccaggatt cataatccat
    24121 gccatggatc agatcacgca ccgcggcaat cggctcccgc tccgccagac gctggatttc
    24181 tgccaaccag tgagtgaagc gggtcaatgc ttcataacca cgtccgctaa gcgtctgact
    24241 caggcccata tcaaagctgg cggtaaacat gcttttattg cgcgtcatcg cccactcacc
    24301 cagctttttc agcgtagccg ggccaatctc tcgcttcggc gtgttaacga tacgcagaaa
    24361 tgcgctgtca tcgtccgggt tagtcagcac gcgcagataa gccagcaagt ccttgatttc
    24421 aggacgagag aaaaacgacg taccaccaga tattttgtac gggatgcggt tttgcatcag
    24481 gaatttttca aacacccgcg actgatggtt accgcgataa agaatggcgt aatctttgta
    24541 ctgcgtttta ttgacgaagt gatgggcgat cagctcgcca gtaacgcgct cagcctcatg
    24601 ttcttcgtta ttcgcgctta atacttttag ctccgcgcca taacccagtt cggagaacag
    24661 acgcttttca aagacgtgcg ggttattggc gatcaggatg ttcgccgctt tcagaatacg
    24721 cccggaagag cgatagttct gctcaagctt aatcaccttc agcgccggaa aatcctgact
    24781 cagcagcacc aggttttgcg gacgtgcacc gcgccaggag tagatcgact ggtcatcgtc
    24841 acccaccacg gtaaagcgcg cgcggctgcc caccagcagt ttcaccagct catactggct
    24901 ggtgttggtg tcctgatact catccaccag cagatagcga attttgttct gccagcgctc
    24961 gcggacttct tcattgcgtt gcagcagcaa cgtcggcaat aaaatcagat catcgaagtc
    25021 gagaacgtta caggctttca ggtgtgcatc atacagccca taacaatggg caaaaatacg
    25081 gtcccgctcg ccaatcgcac ttgctgccgc ctgggacggt gttttgagat cattcttcca
    25141 gttagagatg gtcgaaatca gttgttgcag gagaactttg tcatcttcaa tcagcccctc
    25201 ggtcaactct ttaagcaaag caagctgatc ggtatcgtca aacaacgaga agttcgcttt
    25261 catcccaagc gccgcatact cgcgtttgat gatatccagc cccaacgtat ggaaagtgga
    25321 gatcatcagc ccacgcgcct ctttgcgccc cagcgtctgc cctacacgct ctttcatctc
    25381 gcgcgctgct ttattagtaa aggtcaccgc cgcaatgtgc cgcgcctgat aaccgcaacc
    25441 gcggatcaga tgggcgattt tattggtgat aacacgagtt ttaccggaac ccgcgcccgc
    25501 cagcaccagg caggggccgg taacgaattc gacagcttgt tgttggccgg ggtttagacg
    25561 cataggtgta ttgctcaatc ttcgaacggg gggaggattg tagcagaatc gcatttgaat
    25621 gtgaccgcgt gtaagccgct aaccggttgg ctgcggatgt ttaaatcaga gagagaagac
    25681 cgaaatcgga gttcatcgtg aatccattag acttagaaaa tatcgggtcg taacgttgtg
    25741 ttattacttt ttcagagttt actaaggaga ggtttactcg tggcgattaa tttcagccct
    25801 aaggttggtg aaatactgga atgcaacttt ggtaactatc ctgttagcca aaatggaccg
    25861 ttcagcacga cgtattacga tggccgcatt cctcctgaaa tgataaaaaa caggttagtt
    25921 gtcgtgctca acggaaaaat taatggcaac gcatgcatcg tcgttccatt atcaaccact
    25981 cgcgaccaga caagttaaaa cgtggaatgc atgttgaaat agccagtaat gttatcaatg
    26041 acctgcaatt ctttgatcag cagattcgtt gggccaaagc cgacctggta caacaagtca
    26101 gtcgaaacag attaaacaga gcaaggactt acagagggta tcttaatcaa tgtttgccac
    26161 atgagttggt tgcagacata cagagggcgg tcatcaagtc aatcaatgcc atatcgctca
    26221 taaattgaca ataaaataac catccccgat aatgactttg tagcccatag aggccctaag
    26281 ttttctcccc ttgagggacc tgcgaagccc ggattttccg ggcttttgcc atatatgtac
    26341 cagccactcc ctgactgaca attacgttag catctgcgga tcatgctaaa atcgccgcct
    26401 gacaattatt cactcaaggc acgatcatgg caaaaacagc agcagcactg catatccttg
    26461 taaaagaaga gaaactggct ctggatcttc tcgagcagat taagaacggg gccgatttcg
    26521 gcaagctggc gaagaaacac tccatttgcc catcaggcaa acgcggcggt gatttaggtg
    26581 aattccgcca gggtcagatg gttccggcgt tcgataaagt ggttttctct tgtccggtac
    26641 tggagccgac cggcccgctg cacacccagt tcggatatca catcattaag gtgctgtacc
    26701 gcaactaata gcaaggcctt ctccaggaga aggccttgag tgttttctcc ctctccctgt
    26761 gggagagggt cggggtgagg gcatcagcgc gcacttaacc cgcaacagca atacgtttca
    26821 tatctgtcat atagccgcgc agtttcttac ctacctgctc aatcgcatgg ctgcgaatcg
    26881 cttcgttcac atcacgcagt tgcccgttat ctaccgcgcc ttccggaata gctttaccca
    26941 ggtcgcccgg ttgcagctct gccataaacg gtttcagcaa cggcacacaa gcgtaagaga
    27001 acagatagtt accgtactca gcggtatcag agataaccac gttcatttcg tacagacgct
    27061 tacgggcgat ggtgttggca atcagcggca gctcgtgcag tgattcataa tatgcagact
    27121 cttcaatgat gccggaatcg accatggttt cgaacgccag ttcaacgccc gctttcacca
    27181 tcgcaatcat cagtacgcct ttatcgaagt actcctgctc gccgattttg ccttcatact
    27241 gcggcgcggt ttcaaacgcg gttttgccgg tctcttcacg ccaggtcagc agtttcttat
    27301 catcgttggc ccagtccgcc atcataccgg aagagaattc gccggagatg atgtcgtcca
    27361 tatgtttctg gaacaggggt gccatgatct ctttcagctg ttcagaaagc gcataagcac
    27421 gcagtttcgc cgggttagag agacggtcca tcatcagggt gatgccgccc tgtttcagtg
    27481 cttcggtgat ggtttcccaa ccgaactgaa tcagtttttc tgcgtatgct ggatcggtac
    27541 cttcttccac cagcttgtcg aagcacagca gagagccagc ctgcaacata ccgcacagga
    27601 tggtttgctc gcccatcagg tcagatttca cttccgcaac gaaggacgat tccagcacac
    27661 ccgcacggtg accaccggtt gcagccgccc aggctttggc aatcgccatg ccttcgcctt
    27721 tcggatcgtt ttccgggtga acggcaatca gcgtcggtac gccgaaccca cgtttgtact
    27781 cttcacgcac ttcggtgcct gggcatttcg gcgcaaccat cactacggtg atatctttac
    27841 ggatctgctc gcccacttcg acgatgttga aaccgtgcga gtagcccagc gccgcgccgt
    27901 ctttcatcag tggctgtacg gtgcgcacta catcagagtg ctgcttgtcc ggcgtcaggt
    27961 taatcaccag atccgcctgt gggatcagtt cttcgtaagt acccacttta aaaccatttt
    28021 cggtcgcttt acgccaggac gcgcgcttct cggcaatcgc ttctttacgc agagcgtagg
    28081 agatatcgag accagaatca cgcatgttca ggccctggtt cagaccctgt gcgccacagc
    28141 cgacgatgac tactttttta ccctgaaggt agctcgcgcc atcggcgaat tcatcgcggc
    28201 ccataaagcg acatttgccc agctgtgcca gctgctggcg cagattcagt gtattgaagt
    28261 agttagccat ggtgattcct cgtgatgttg tgcttcttat tgttcggttc gcgtttgcga
    28321 gattgaattc actatatgac aggaaattta ttgcggaaat tgatatattc acaacgtcac
    28381 attgcaattt ttgcaacgtc aacatcgagg gctgtccctg tggatttacg cgatctgaaa
    28441 accttcctgc atctggcgga aagccgccat tttggccgca gcgcgcgggc gatgcacgtt
    28501 agcccatcca cgctctcacg gcagattcag cgcctggaag aagatctcgg tcagccgctg
    28561 tttgtgcgcg ataaccgcac ggtgacgctg actgaagcgg gcgaagagct gcgcgttttc
    28621 gcccagcaaa cgctgttgca gtatcagcag ttgcgccaca ccatcgatca gcaagggccg
    28681 tcgctctctg gcgaattaca tatcttctgc tcggtgaccg ctgcctacag ccatctgccg
    28741 ccgattctgg atcgcttccg cgcggaacac ccgtcggtgg agattaaact tactactggt
    28801 gatgcggcag atgcgatgga aaaggtggtc actggtgaag cggatctggc gattgcgggt
    28861 aaaccggaaa ccttgcccgg cgcagtggcg ttttcgatgc tggagaatct ggcagtagtg
    28921 ctgattgccc ccgcgctgcc ctgcccggtg cgtaatcagg tgtcggtaga gaagccggac
    28981 tggtcaacgg tgccgtttat tatggccgat caggggccgg tacgccgccg cattgaactg
    29041 tggtttcgac gcaataaaat cagtaacccg atgatttacg ccacggttgg cgggcatgaa
    29101 gcgatggtat cgatggtggc actcggctgt ggcgtggcat tgttgccgga agtggtgctg
    29161 gaaaacagcc ccgaaccggt gcgtaaccgc gtgatgattt tagagcgcag cgatgagaaa
    29221 acgccgtttg agctgggcgt gtgtgcgcag aaaaagcggc tacatgagcc gctaattgag
    29281 gcattctgga agattttgcc gaaccacaaa tgacgttgtc gcgcgggtag gcctgataag
    29341 cgaagcgcta tcaggcattt ttccctaacc cgccaaaaag aacctgaacg ccgggttatt
    29401 ggtttcgtcg tggcaatcgt agcccagctc attcagccgg gtttcgaaat ccggttcatg
    29461 gtcgccaagt tcgaacgccg ccagtacgcg cccgtagtcg gtgccatggc tgcgatagtg
    29521 gaacaaagaa atgttccagt acgtacccag cgtgttgagg aagcgcagca gcgcgcccgg
    29581 tgattccggg aattcgaagc tgtagaggcg ttcctgcaac ggatgcgatg gacgtccgcc
    29641 gaccatatag cgcacgtgta gcttcgccat ttcgtcgtcg gagagatcaa ccacgctgta
    29701 gccgccgtcg ttgagcatct gcaaaatttc tttgcgctct tcgaggccgc ggctcaggcg
    29761 cacaccgaca aagatgcagg cgtttttggc atcggcaaaa cggtagttga actcggtgac
    29821 cgaacgcccg ccaagcagtt ggcagaattt gaggaagctg cctttttctt ccggaatggt
    29881 caccgccaac aacgcttcac gctgttcgcc cagttcgcag cgttctgaga cgtagcgcag
    29941 gccgtggaag ttcacgttgg caccggaaag aatatgcgcc agccgttcgc cgcgaatgtt
    30001 gtgcagggcg atatattttt tcattcccgc cagcgccagc gcgccagagg gttccgccac
    30061 cgcgcgcaca tcttcgaata aatccttcat cgccgcacag atcgcatcgc tatcgacggt
    30121 gatgatgtcg tcgagatact cctggcataa acggaaggtt tcgtcaccga tgcgttttac
    30181 cgctacgcct tcagcaaata gccctacgcg cggcagatca accggatgac ccgcatccag
    30241 cgctgctttc aggcaggcgg agtcttccgc ttctacggcg atcactttga tttgcggcat
    30301 cagttgtttg atcagcaccg ccacgccagc agccagaccg ccgccgccga ctggcacaaa
    30361 tacgcggtcg agatgggcgt cctgctggag cagttccagc gccagcgtgc cttgcccggc
    30421 aatcaccatc ggatggtcga acggcggcac ccaggtgaac ccctgctgct gtgacagttc
    30481 gatcgctttg gctttcgctt catcaaagtt cgcgccgtgg agcagcactt cgccgccgaa
    30541 gccgcgcacc gcgtcgactt tgatgtcggc ggtggcggtt ggcataacga tcagggcctt
    30601 cacgcctaac cgcgcagaag aaaacgcgac gccctgcgcg tggttacccg cagaagcagt
    30661 gatcacgccg tgcgctttct gttcttccgt caggcccgcc atcatggcgt atgcgccgcg
    30721 cagcttaaag ctgtgcactg gctggcgatc ttcgcgcttc accagaatga cgttatcaag
    30781 acgcgacgac agtttttcca ttttttgtag cggcgtaacc tgcgccgcct cgtaaaccgg
    30841 cgcgcgcagc actgctctta aatattcggc accttccgga gcaccggaca ggggttgcga
    30901 gtcagccatt attaaccccc cagtttcgat ttatcgcgca ccgcgccttt gtcggcgctg
    30961 gttgccaggc tggcataagc acgcagggca aaggagacct gacgttcacg atttttcggc
    31021 gtccaggctt tgtcacctcg agcgtcctgc gcttcacgac gcgccgccag ttcggcatcg
    31081 cttacctgta actgaatgcc acggttcggg atgtcgatag cgatcaggtc accatcttca
    31141 atcaggccaa tgctgccgcc gcttgccgct tccggtgaga cgtggccgat ggaaagacca
    31201 gaggtgccac cagagaaacg accgtcggtg atcagcgcac aggctttgcc gagacccatt
    31261 gatttcagga agctggttgg gtagagcatt tcctgcatcc ccggaccgcc tttcgggcct
    31321 tcatagcgaa ttactaccac atctccggcg acaactttac cgccgagaat cgcttctacc
    31381 gcatcgtcct ggctttcgta cactttcgcc gggccggtga atttgaggat gctgtcatcg
    31441 acgcctgccg ttttcacgat gcagccgttt tccgcaaagt taccgtagag caccgccagg
    31501 ccgccgtctt tgctgtaggc gtgttccagc gagcggatac agccattggc gcgatcgtcg
    31561 tccagcgtat cccaacggca atcttgcgag aatgcctgtg tggtacgaat gcctgcagga
    31621 cctgcgcgga acatattttt taccgcgtca tcctgggtca gcataacgtc gtattgttcc
    31681 agcgtttgcg gcaacgtcag gccaagtacg tttttcacat cacggttcag taaccccgcg
    31741 cgatccagtt cgccgagaat accgataaca ccaccagcac ggtgaacatc ttccatatgg
    31801 tatttctggg tgctcggcgc aactttacac agctgtggaa ccttgcggga aagcttatcg
    31861 atatcactca tggtgaagtc gatttccgct tcctgcgccg ccgccagcag gtgaagtacg
    31921 gtgttagtcg atccacccat cgcgatatcc agcgtcatgg cgttttcaaa cgccgcctta
    31981 ctggcgatat tacgcggcag tgcactttcg tcgttttgct cgtaataacg tttggtcaat
    32041 tcaacaatgc gtttaccagc attaaggaac agctgcttac ggtcggcgtg ggttgccagc
    32101 agcgagccgt tgcccggctg cgacaggccc agcgcttcgg tcaggcagtt cattgagtta
    32161 gcggtaaaca tcccggagca ggaaccgcag gtcggacacg cggaacgttc aacctgatcg
    32221 ctctgggagt cagatacttt cgggtctgcg ccctggatca tcgcatcaac cagatcgagc
    32281 ttgatgatct gatcggaaag tttggttttc ccggcctcca tcgggccgcc ggaaacaaag
    32341 atcaccggaa tattcaggcg cagggaagcc atcagcatcc ccggggtgat tttgtcgcag
    32401 ttagagatgc agaccatggc gtcggcgcag tgggcgttga ccatatactc aacggaatca
    32461 gcgatcagtt cgcgagatgg cagtgaataa agcatccccc cgtggcccat ggcaatccca
    32521 tcatccaccg caatggtgtt gaactctttg gcaacgccgc cagccgcttc aatttgttcg
    32581 gcgaccagtt taccgagatc gcgcagatgg acgtgacccg gtacaaattg ggtgaacgag
    32641 ttcacaaccg cgataatcgg cttaccgaaa tcggcgtcgg tcattccggt ggcgcgccac
    32701 agcgcacgag cacccgccat attacgacca tgagtggtgg tggcggaacg gtacttaggc
    32761 atactttatt tactcccagt gtctgtctcg taaatgggac ggtgcgtgcc gtcccatttt
    32821 ttgtatttat tgattaactt gatctaacca gccccattta tcttcggttt cgccagtgaa
    32881 gaggccgaag aaggcttgct gaatgcgttt ggtaaccggg ccacaacggc cttcgccaac
    32941 ctgaataccg tctacgctgc gcactggcgt gatttctgcc gccgtaccgg acataaacac
    33001 ttcatccgcc aggtacaggg attcgcgcga cagcacctgc tcacgtactt caattcccag
    33061 ctctttcgcc agtttgatga tggcatcacg ggtaataccc ggcagcgcgg aggaggtgaa
    33121 cggtggggtg aacagcacac catctttcac ttcaaacagg ttttcgcctg cgccttcaga
    33181 gatataaccg ttcacatcca gcgcgatacc ttcctgataa ccgtggcggc gcgcttcgct
    33241 acccaccagc agggaagaga ggtagttacc accggctttt gccgccgtcg ggatggtgtt
    33301 tggtgctgcg cggttccagg aggaaaccat cgcatcgatc ccctgctcca gcgcttctgc
    33361 gcccagatac gctccccacg ggaaagcagc gataatcacg tcggttgagt atcccgctgg
    33421 cgggtttact cccatgccaa catcaccgac gaagatcagc ggacggatat aggcgctggt
    33481 gagattgttt ttgcggatca cgtcacgaca agcttccatc agctcatcaa tgctctgcga
    33541 aaccgggaag cgatagattt tggcggagtc atgcagacgc tgcatatgct cacgatggcg
    33601 gaatacaacc ggtcctttgt gcgagtcgta gcaacggatg ccttcaaaaa ccgaagtgcc
    33661 atagtgcagc gcgtgcgaca tcacatgcac cttcgcgtct tcccagcgaa ccatctcccc
    33721 attgaaccaa atgtaatcag ctttcttcgt ggtcattttt atattccttt tgcgctcagg
    33781 cgcggatttg ttgtgatgtg gttgtgctct ggcagatggc aacgtgtgcg acgtccacca
    33841 gtttatttaa ctgactaaac agtaagtcga ccgaccgtgg gctggcaacg gtcaattcga
    33901 tatttatatt ttgtgcatcg ctggcggcgg ccatattcat tgagcagacg tggaaaccac
    33961 gatgacgcac cacgcgtaaa acacgttcta aggtttctgg attgaagcga gccgatacat
    34021 tgacctgatg ttgcatcatg ataatttctc caacatttct gaattactgg cgccaggcgg
    34081 caccagcggc cagacgttct caagttcgtc gattgagaca tgaagcaggt atggcccatc
    34141 actgttcagc atggtgtcga gtgccgcttc aacctggtct ttccgggtga tgtgttggcc
    34201 atggatgccg aaggcgctgg ctaacatgag gaaatcgggg ttatcagtaa gggtggtttc
    34261 gctgtatcgt tcctgaaaaa acagttgctg ccattgtcga accatcccta accgttggtt
    34321 atcgagtaag acgattttca acggtaactg cttgcgtttt acggtgccca gctcttgcac
    34381 attcatcatg aaagagccgt caccggagat acagacaacg gtatcgttcg gtcgcgcgac
    34441 ttgtgcgcca accgccgccg gtaaaccaaa acccatggta cctaaaccgc tggaggtgat
    34501 gaaattttcc gggcgagtgt gggcgatgtg ctgcgcagcc cacatctggt gctgccccac
    34561 atctgtggtc acgacgcaat ccgcaggttt acgatccgac agttgtttta acaacaacgg
    34621 cgcgtagata gcgtcaccgg gatggtcgta acgccaggaa tgttcatcac gcagctgcgc
    34681 gcagtgttgc tgccagtcat tgatatttaa cggctgctgt aatgctggta acagagcatt
    34741 taaatcacct tgtaatgcca catgtgcctg acgcagcttg ttcatttctg ccgggtcgat
    34801 atccatatgg ataacactgg cgtgtggcgc gaaggtgttc agtttgccgg tcacccggtc
    34861 atcaaaacgt gcgcccacgg cgatcagcag gtcacactcc tgcaccgcga agtttgccgc
    34921 tttggtgccg tgcatcccca gcatgcccag atagtacgga taatctgctt ctactgcgcc
    34981 cagccctttc agcgtacagg tggcaggcat ttttgtggca gcgagaaatt cacgcaaagc
    35041 cggaactgcc tgcgccatac ccacgccacc gccaacgtac agcatcggtt tttgcgcttt
    35101 tgccagcatc tggcgcgctt gctcaacttc ggcatgtggg aaagtcactt cgttttcaac
    35161 ggtggtgaac cacggttcca ggtcaccgct ggctaactgg atatcttttg ggatatcgac
    35221 cagaaccgga ccaggacgac ctgagcaggc aacgtcgaat gcttcagcca tgatgcgcgg
    35281 caactcttcc agcgactgca ccagaaagct gtgcttggta caggctaacg acaatcccag
    35341 gacatccact tcctgaaatg cgtcagtgcc gataaacggt gcggacactt gaccggtgat
    35401 ggcaacaaca gggatggaat ctaacagtgc gtccgcaagc ccggttatca ggttggttgc
    35461 gcccggacca gacgtggcga tacatacgcc agttttgccg gtagcacgag cataaccgat
    35521 agccgccatt gccgcaccct gctcatgtcg gcatagcaag tgctccacgc cgccgtcata
    35581 caatgcatcg taaaccggca taattgcgcc acccggataa ccgaaaacgg tgttcacacc
    35641 ctgtgcccgc aacgcatgta ccacccactg tgcgccattc atagttagtt ccccgtcctg
    35701 aatcttgaga aacagaattt tgtgctgtta ttcattgtct gctcctcggt tatgttttta
    35761 aggtcaaaaa aaacccccgg acctttcggt gcgggggtct tagttcgtta aggcttgatc
    35821 tctaagcctt tcctcgtcca agtgcagccc cgcacggtgg gataataatc accaccacgc
    35881 taatcacgac caggctaatc actcgtagaa gggctgtcat tttgtctttt cttgcatctt
    35941 gttcgaagga atgtctaaag agttaccata ggttttgtaa atagtacaag atattttttg
    36001 gccgattttt atgatgcgtt taataatttc aatataaatt gttgtttttt aaaaataaaa
    36061 tagtgagtga aaaaaattca atttcagtat gaatgttgtt cccttcctcg tagttcatcc
    36121 tttgtccgct gcatttttgc gagcatcatt ccaccgccag aacaactcaa cttcacttgc
    36181 acaaataaac aggaatcagc cactaaaatt cacgaattag cgggctacag cagcgatatc
    36241 ttatgcacat aatggtgact caaggagggc ttatgtcact gtcaattgtt catacccgcg
    36301 cagccctggg agtaaatgcg cccccgatca ctgttgaggt acatatcagt aaaggtctac
    36361 ccggcttaac gatggtgggc ttaccagaaa caacggtaaa agaagctcgc gatcgcgtgc
    36421 gcagcgccat tatcaatagc ggatatgaat atccggcgaa aaaaatcacc atcaacctgg
    36481 ctccagctga tctgccaaaa gaagggggac gatatgattt acctatcgcc attgcgttgc
    36541 tggcggcctc agaacagctt acagccaata agttagatga atatgaatta gtcggagaac
    36601 tggcgcttac aggcgctctg cgtggcgttc ccggcgcaat ctccagtgca actgaagcta
    36661 ttaagtcggg cagaaaaatt atcgtcgcga aagataacga agatgaagtg gggctaatta
    36721 acggtgaagg atgcctgata gccgatcatc tgcaagctgt ctgtgcgttt ctggaaggta
    36781 agcacgctct cgaacgcccg aaaccaactg atgcagtatc ccgggcgcta caacatgatc
    36841 tcagtgatgt tatcggtcag gaacaaggaa agcgaggact ggaaattacc gctgctggcg
    36901 ggcacaacct tttactgatt gggccgccgg gaacaggtaa aacaatgctc gccagccgta
    36961 ttaatggcct gttgccagat ttaagcaatg aagaggcact ggagagtgct gcgatattaa
    37021 gtctggtaaa tgctgaatca gtacaaaaac aatggcggca gcgcccgttc cgctcacctc
    37081 atcacagtgc atcgttaact gcgatggtag gcggtggcgc aattccaggg cccggtgaaa
    37141 tttcgctggc gcataacggc gtgctttttc ttgatgagct acctgaattt gaacggcgta
    37201 cactggatgc cttgcgagag ccgattgaat ccgggcagat ccatctttca cgcacacgag
    37261 caaaaataac ctatccagcc cgtttccagc ttgttgcggc gatgaatccc agccctaccg
    37321 gacattatca gggaaaccat aaccgctgca cgccagaaca gacattacgt tatctcaacc
    37381 ggctctcggg gccctttctc gaccgcttcg atctctcact ggagatccca ttaccacccc
    37441 ccggcatttt gagtaaaacg gtagtgccgg gagaaagcag cgccaccgtt aaacaacgcg
    37501 taatggccgc cagagagcgc caatttaagc ggcagaataa actgaatgcc tggctggata
    37561 gtccggaaat acgccaattc tgcaaacttg agagcgaaga tgcgatgtgg ttggaaggaa
    37621 cactgatcca tctggggtta tcgattcgtg cctggcagcg gttattgaaa gttgcacgaa
    37681 ccattgctga tattgatcag tctgacatta tcacacgtca gcatttgcag gaggcagtta
    37741 gctatcgagc gattgaccgt ttgctcatcc atctgcagaa actactgaca taaaaaaagg
    37801 gcatttcgcc ctttttatta atcgtcagaa tcggtgtagt cttcagcacc ttcaacctgc
    37861 ggtttaccgc cggaaagggt gtgaaaacgt tttggacgct taatacgcgt catatacttg
    37921 gaccacacgc gttctgcttc tgtcactggc tcacgttcgc cacggcatac tgctacgaag
    37981 agtttctctt cctcggtaac cggctcgcgt ttgccaagat ccaactcatt gaaggcataa
    38041 ccatgacgct caagcagttg tgcctctttg atggtgaaat caccatgacg agagaatcca
    38101 cgtggataat gtttattgtc gaaatatcga ttagtcgtcg taaagctttc cgccatcctg
    38161 cacgctccta attctttgac cgagctagtt atggcgcgga gtattagtta cgcttgacag
    38221 agtgtaaaac aaaacattta aatcataacg acaaataatt ttgcggagag cactgtggat
    38281 acggaattgt taaaaacttt cctggaagtt agccgaacgc gtcactttgg tcgagcggct
    38341 gaatcgctct atctgaccca gtcagcagtg agctttcgaa tcagacaact ggaaaatcaa
    38401 ctgggtgtga accttttcac ccgccacaga aacaatatcc gtttaaccgc tgccggtgaa
    38461 aaactactgc cttatgcaga aacgctcatg agcacctggc aggccgcccg taaggaggtg
    38521 gcgcatacct cacgacataa cgagttttct atcggtgcca gcgcctcgtt gtgggaatgt
    38581 atgcttaatc agtggctggg acgcttgtat caaaatcagg atgcccatac aggcttacag
    38641 ttcgaagcgc gaattgccca acggcagtct ctggtaaaac agctgcatga acgccagctt
    38701 gatcttctta ttaccactga agcgcccaaa atggacgaat ttagtagtca gttgctggga
    38761 tatttcactt tagcgcttta taccagtgcc ccttcaaaac taaagggaga tcttaattat
    38821 ctgcgacttg agtgggggcc agattttcaa cagcatgagg caggtttgat cggtgctgac
    38881 gaagtgccca ttctgacaac cagttctgct gaactggcac agcaacagat tgcgatgctt
    38941 aatggttgca cctggctacc cgtcagctgg gcgcgtaaaa aaggcggcct gcataccgtt
    39001 gtcgatagca caacactttc acggccgctt tatgccatat ggctgcaaaa tagcgataaa
    39061 aatgcgttga ttcgcgatct tttgaaaatt aacgtgctgg atgaagtgta ttaatatgaa
    39121 tggctggcaa ggatgccggt agaaggattt acttcggaga gggttatttc agataaaaaa
    39181 aatccttagc tttcgctaag gatgatttct ggcaggggcg gagagactcg aactcccaac
    39241 acccggtttt ggagaccggt gctctaccaa ttgaactacg cccctaatta gggtggcgga
    39301 acggacggga ctcgaacccg cgaccccctg cgtgacaggc aggtattcta accgactgaa
    39361 ctaccgctcc accgaattct tttacaacca ccggttttat gaccggctta ctgctt
//
LOCUS       DAPOAV010000037        39331 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.037, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000037 DAPOAV010000000
VERSION     DAPOAV010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 39331)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39331)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39331
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.037"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(104..799)
                     /gene="aqpZ"
                     /locus_tag="RN951_002202"
     CDS             complement(104..799)
                     /gene="aqpZ"
                     /locus_tag="RN951_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin Z"
                     /protein_id="HDX2527194.1"
                     /translation="MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFG
                     LTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLI
                     ASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAG
                     FAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGII
                     GGLIYRTLLEKRD"
     gene            1225..2883
                     /locus_tag="RN951_002203"
     CDS             1225..2883
                     /locus_tag="RN951_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent endonuclease"
                     /protein_id="HDX2527195.1"
                     /translation="MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTL
                     LLSPESDLYHFERDDFWYPPGDINGREHHLHIILTFRESLPGRHRVRRYRPLEACWTP
                     CTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQARHLVRLMPVLRLR
                     DARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEH
                     YFSEQGAGQARYRLMRRRASNEQRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQA
                     KGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIATTNSGELLSLTPVE
                     HVCRLVRESSRVAAWRLGPSGLSTEDSRRISFHIRFNRPSSLFARCWLLVEGETETWV
                     INELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATV
                     RSLLNNDREAEREHLTALPALDMEHFMYRQGFSDVFHRMAQIPENVPMNLRKIISKAI
                     HRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD"
     gene            complement(2880..3836)
                     /locus_tag="RN951_002204"
     CDS             complement(2880..3836)
                     /locus_tag="RN951_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001322270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF535 domain-containing protein"
                     /protein_id="HDX2527196.1"
                     /translation="MNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQ
                     KFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEAL
                     RYHYALLRECMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILF
                     RNSEGIPLAEITFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVM
                     EAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHY
                     RLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFRG"
     gene            3987..5102
                     /gene="macA"
                     /locus_tag="RN951_002205"
     CDS             3987..5102
                     /gene="macA"
                     /locus_tag="RN951_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415399.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide transporter subunit MacA"
                     /protein_id="HDX2527197.1"
                     /translation="MKKRKTVKKRYVIALVIVIAGLITLWRILNAPVPTYQTLIVRPG
                     DLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIK
                     EVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTKAVSQQDLDTAATEMAVKQAQI
                     GTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLA
                     DMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKVNDAIFYY
                     ARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETR
                     EREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ"
     gene            5099..7045
                     /gene="macB"
                     /locus_tag="RN951_002206"
     CDS             5099..7045
                     /gene="macB"
                     /locus_tag="RN951_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide ABC transporter ATP-binding
                     protein/permease MacB"
                     /protein_id="HDX2527198.1"
                     /translation="MTPLLELKDIRRSYPAGDEQVEVLKGISLDIYAGEMVAIVGASG
                     SGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLT
                     AEQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALM
                     NGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRD
                     GEIVRNPPAIEKVNVTGGTEPVVNTVSGWRQFVSGFNEALTMAWRALAANKMRTLLTM
                     LGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYD
                     DLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQ
                     EQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVL
                     RVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMD
                     GVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARAS
                     DVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVT
                     GILFGWLPARNAARLDPVDALARE"
     gene            complement(7118..7342)
                     /gene="cspD"
                     /locus_tag="RN951_002207"
     CDS             complement(7118..7342)
                     /gene="cspD"
                     /locus_tag="RN951_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspD"
                     /protein_id="HDX2527199.1"
                     /translation="MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKA
                     GQSVQFDVHQGPKGNHASVIVPVEVEAAVA"
     gene            7665..7985
                     /gene="clpS"
                     /locus_tag="RN951_002208"
     CDS             7665..7985
                     /gene="clpS"
                     /locus_tag="RN951_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease adapter ClpS"
                     /protein_id="HDX2527200.1"
                     /translation="MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVI
                     DVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCT
                     LEKA"
     gene            8016..10292
                     /gene="clpA"
                     /locus_tag="RN951_002209"
     CDS             8016..10292
                     /gene="clpA"
                     /locus_tag="RN951_002209"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpA"
                     /protein_id="HDX2527201.1"
                     /translation="MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREAL
                     EACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNE
                     VTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSE
                     EQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGV
                     GKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQ
                     DTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKD
                     RALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDR
                     HLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLK
                     NLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQL
                     SKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEI
                     EKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDN
                     STDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEV
                     SQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKN
                     ELTYGFQSAQKHKAEAAH"
     gene            complement(10636..10723)
                     /locus_tag="RN951_002210"
     tRNA            complement(10636..10723)
                     /locus_tag="RN951_002210"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10687..10689),aa:Ser,seq:gga)
     gene            complement(10977..11195)
                     /gene="infA"
                     /locus_tag="RN951_002211"
     CDS             complement(10977..11195)
                     /gene="infA"
                     /locus_tag="RN951_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HDX2527202.1"
                     /translation="MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNY
                     IRILTGDKVTVELTPYDLSKGRIVFRSR"
     gene            complement(11480..12184)
                     /gene="aat"
                     /locus_tag="RN951_002212"
     CDS             complement(11480..12184)
                     /gene="aat"
                     /locus_tag="RN951_002212"
                     /EC_number="2.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl/phenylalanyl-tRNA--protein transferase"
                     /protein_id="HDX2527203.1"
                     /translation="MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQR
                     GIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGC
                     ASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFS
                     RMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGR
                     LPNNFWVPRCLFSPQE"
     gene            complement(12226..13947)
                     /gene="cydC"
                     /locus_tag="RN951_002213"
     CDS             complement(12226..13947)
                     /gene="cydC"
                     /locus_tag="RN951_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter ATP-binding
                     protein/permease CydC"
                     /protein_id="HDX2527204.1"
                     /translation="MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLS
                     ASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSK
                     LLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDF
                     TLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGA
                     SDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQP
                     GALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRISDLTDQKPEVTFPDTQTRVA
                     DRVSLTLRDVQFTYPEQSQQALKGISLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDP
                     QQGEILLNDSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALSEIL
                     RRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDAT
                     TESQILELLAEMMREKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRY
                     YQFKQGL"
     gene            complement(13948..15714)
                     /gene="cydD"
                     /locus_tag="RN951_002214"
     CDS             complement(13948..15714)
                     /gene="cydD"
                     /locus_tag="RN951_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter
                     permease/ATP-binding protein CydD"
                     /protein_id="HDX2527205.1"
                     /translation="MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWF
                     MARILQHMIMENIPREALLLPFTLLVLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQV
                     LDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFP
                     SNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIF
                     GRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGEL
                     DFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAH
                     PQRGEAELASTDPVTIEAEELFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSL
                     LNALSGFFSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDA
                     SEQELQAALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLL
                     LDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGRIIEQGR
                     YAELSVAGGPFATLLAHRQEEI"
     gene            complement(15837..16802)
                     /gene="trxB"
                     /locus_tag="RN951_002215"
     CDS             complement(15837..16802)
                     /gene="trxB"
                     /locus_tag="RN951_002215"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDX2527206.1"
                     /translation="MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQL
                     TTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLNGDNG
                     EYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
                     EALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGV
                     TGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQ
                     TSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK"
     gene            17347..17841
                     /gene="lrp"
                     /locus_tag="RN951_002216"
     CDS             17347..17841
                     /gene="lrp"
                     /locus_tag="RN951_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001591745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-responsive transcriptional regulator
                     Lrp"
                     /protein_id="HDX2527207.1"
                     /translation="MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTP
                     CLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEE
                     IQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLV
                     IKTR"
     gene            17976..21965
                     /gene="ftsK"
                     /locus_tag="RN951_002217"
     CDS             17976..21965
                     /gene="ftsK"
                     /locus_tag="RN951_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDX2527208.1"
                     /translation="MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSF
                     NPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQS
                     SDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHS
                     SGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYE
                     DDEEYEDENHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDE
                     EITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWA
                     APVEPVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQ
                     YNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQ
                     TEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRARERE
                     QLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAA
                     TVAAPVFSLANSGGPRPQVKEGIGPQLPRPKRIRVPTRRELASYGIKLPSQRAAEEKA
                     REAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAEDADAAA
                     EAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMKALLDDGPHEPLFTPIVEPVQ
                     QPQQPVAPQQQYQQPQQPVPPQPQYQQPQQPVAPQPQYQQPQQPVAPQQQYQQPQQPV
                     APQQQYQQPQQPVAPQPQDTLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPV
                     DTFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLA
                     RSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDI
                     AGEPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELS
                     VYEGIPHLLTEVVTDMKDAANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRM
                     MRPIPDPYWKPGDSMDAQHPVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKAR
                     AAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDM
                     LYSGPNSTLPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGA
                     EELDPLFDQAVQFVTEKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNR
                     EVLAPPPFD"
     gene            22124..22735
                     /gene="lolA"
                     /locus_tag="RN951_002218"
     CDS             22124..22735
                     /gene="lolA"
                     /locus_tag="RN951_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein chaperone LolA"
                     /protein_id="HDX2527209.1"
                     /translation="MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQK
                     VTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWL
                     KDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQ
                     FSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK"
     gene            22746..24089
                     /gene="rarA"
                     /locus_tag="RN951_002219"
                     /gene_synonym="mgsA"
     CDS             22746..24089
                     /gene="rarA"
                     /locus_tag="RN951_002219"
                     /gene_synonym="mgsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein
                     RarA"
                     /protein_id="HDX2527210.1"
                     /translation="MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAAGKPLPRA
                     IEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNR
                     NAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVY
                     LLKSLSTEDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMM
                     ADMAEVDDSGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALY
                     WYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIA
                     QAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYA
                     HDEANAYAAGEVYFPPEIAQTRYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR"
     gene            24180..25472
                     /gene="serS"
                     /locus_tag="RN951_002220"
     CDS             24180..25472
                     /gene="serS"
                     /locus_tag="RN951_002220"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDX2527211.1"
                     /translation="MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKT
                     ENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALT
                     IPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGS
                     RFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLF
                     HTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGR
                     DTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMG
                     FGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSG
                     LAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG"
     gene            25711..28155
                     /gene="dmsA"
                     /locus_tag="RN951_002221"
     CDS             25711..28155
                     /gene="dmsA"
                     /locus_tag="RN951_002221"
                     /EC_number="1.8.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415414.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit A"
                     /protein_id="HDX2527212.1"
                     /translation="MKTKIPDAVLAAEVSRRGLVKTTAIGGLAMASSALTLPFSRIAH
                     AVDSAIPTKSDEKVIWSACTVNCGSRCPLRMHVVDGEIKYVETDNTGDDNYDGLHQVR
                     ACLRGRSMRRRVYNPDRLKYPMKRVGARGEGKFERISWEEAYDIIATNMQRLIKEYGN
                     ESIYLNYGTGTLGGTMTRSWPPGNTLVARLMNCCGGYLNHYGDYSSAQIAEGLNYTYG
                     GWADGNSPSDIENSKLVVLFGNNPGETRMSGGGVTYYLEQARQKSNARMIIIDPRYTD
                     TGAGREDEWIPIRPGTDAALVNGLAYVMITENLVDQAFLDKYCVGYDEKTLPASAPKN
                     GHYKAYILGEGPDGVAKTPEWASQITGVPADKIIKLAREIGSTKPAFISQGWGPQRHA
                     NGEIATRAISMLAILTGNVGINGGNSGAREGSYSLPFVRMPTLENPIQTSISMFMWTD
                     AIERGPEMTALRDGVRGKDKLDVPIKMIWNYAGNCLINQHSEINRTHEILQDDKKCEL
                     IVVIDCHMTSSAKYADILLPDCTASEQMDFALDASCGNMSYVIFNDQVIKPRFECKTI
                     YEMTSELAKRLGVEQQFTEGRTQEEWMRHLYAQSREAIPELPTFEEFRKQGIFKKRDP
                     QGHHVAYKAFREDPQANPLTTPSGKIEIYSQALADIAATWELPEGDVIDPLPIYTPGF
                     ESYQDPLNKQYPLQLTGFHYKSRVHSTYGNVDVLKAACRQEMWINPLDAQKRGIHNGD
                     KVRIFNDRGEVHIEAKVTPRMMPGVVALGEGAWYDPDAKRVDKGGCINVLTTQRPSPL
                     AKGNPSHTNLVQVEKV"
     gene            28166..28783
                     /gene="dmsB"
                     /locus_tag="RN951_002222"
     CDS             28166..28783
                     /gene="dmsB"
                     /locus_tag="RN951_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HDX2527213.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDYKDLTPEVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCPSGAMHKREDGFVVVDEDVCIGC
                     RYCHMACPYGAPQYNETKGHMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRK
                     KHGDLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPKEV"
     gene            28785..29648
                     /gene="dmsC"
                     /locus_tag="RN951_002223"
     CDS             28785..29648
                     /gene="dmsC"
                     /locus_tag="RN951_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit
                     DmsC"
                     /protein_id="HDX2527214.1"
                     /translation="MGSGWHEWPLMIFTVFGQCVAGGFIVLALALLKGDLRAEAQQRV
                     IACMFGLWVLMGIGFIASMLHLGSPMRAFNSLNRVGASALSNEIASGSIFFAVGGIGW
                     LLAMLKKLSPALRTLWLIVTMVLGVIFVWMMVRVYNSIDTVPTWYSIWTPMGFFLTMF
                     MGGPLLGYLLLSLAGVDGWAMRLLPAISVLALVVSGVVSVMQGAELATIHSSVQQAAA
                     LVPDYGALMSWRIVLLAVALCLWIAPQLKGYQPAVPLLSVSFILLLAGELIGRGVFYG
                     LHMTVGMAVAS"
     gene            complement(29683..30309)
                     /locus_tag="RN951_002224"
     CDS             complement(29683..30309)
                     /locus_tag="RN951_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDX2527215.1"
                     /translation="MTKPYVRLDKNDAAVLLVDHQAGLLSLVRDIEPDKFKNNVLALG
                     DLAKYFNLPTILTTSFETGPNGPLVPELKAQFPDTPYIARPGNINAWDNEDFVKAVKA
                     TGKKQLIIAGVVTEVCVAFPALSAIEEGFDVFVVTDASGTFNEITRHSAWDRLSQAGA
                     QLMTWFGVACELHRDWRNDIEGLATLFSNHIPDYRNLMTSYDTLTKQK"
     gene            30623..31771
                     /locus_tag="RN951_002225"
     CDS             30623..31771
                     /locus_tag="RN951_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2527216.1"
                     /translation="MSTYTQPVMLLLSGLLLLTLAIAVLNTLVPLWLAQEHMSTWQVG
                     VVSSSYFTGNLVGTLLTGYVIKRIGFNRSYYLASFIFAAGCAGLGLMIGFWSWLAWRF
                     VAGVGCAMIWVVVESALMCSGTSRNRGRLLAAYMMVYYVGTFLGQLLVSKVSTELMSV
                     LPWVTGLTLAGILPLLFTRVLNQQAENHDSTSITSMLKLRQARLGVNGCIISGIVLGS
                     LYGLMPLYLNHKGVSNASIGFWMAVLVSAGILGQWPIGRLADKFGRLLVLRVQVFVVI
                     LGSIAMLSQAAMAPALFILGAAGFTLYPVAMAWACEKVEHHQLVAMNQALLLSYTVGS
                     LLGPSFTAMLMQNFSDNLLFIMIASVSFIYLLMLLRNAGHTPKPVAHV"
     gene            31981..33411
                     /locus_tag="RN951_002226"
     CDS             31981..33411
                     /locus_tag="RN951_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415419.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDX2527217.1"
                     /translation="MAGNVQEKQLRWYNIALMSFITVWGFGNVVNNYANQGLVVVFSW
                     VFIFALYFTPYALIVGQLGSTFKDGKGGVSTWIKHTMGPGLAYLAAWTYWVVHIPYLA
                     QKPQAILIALGWAMKGDGSLIKEYSVVALQGLTLVLFIFFMWVASRGMKSLKIVGSVA
                     GIAMFVMSLLYVAMAVTAPAITEVHIATTNITWETFIPHIDFTYITTISMLVFAVGGA
                     EKISPYVNQTRNPGKEFPKGMLCLAVMVAVCAILGSLAMGMMFDSRNIPDDLMTNGQY
                     YAFQKLGEYYNMGNTLMVIYAIANTLGQVAALVFSIDAPLKVLLGDADSKYIPASLCR
                     TNASGTPVNGYFLTLVLVAILIMLPTLGIGDMNNLYKWLLNLNSVVMPLRYLWVFVAF
                     IAVVRLAQKYKPEYVFIRNKPLAMTVGIWCFAFTAFACLTGIFPKMEAFTAEWTFQLA
                     LNVATPFVLVGLGLIFPLLARKANSK"
     gene            complement(33412..34320)
                     /locus_tag="RN951_002227"
     CDS             complement(33412..34320)
                     /locus_tag="RN951_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX2527218.1"
                     /translation="MRMNMSDFATFFAVARNQSFRAAGDELGLSSSAISHSIKTLEQR
                     LKIRLFNRTTRSVSLTEAGSNLYERLRPAFDEIQIMLDEMNDFRLTPTGTLKINAARV
                     AARIFLMSLLVGFTREYPDIKVELTTDDSLVDIVQQGFDAGVRLSCIVEKDMISVAIG
                     PPVKLCVAATPEYFARYGKPRHPHDLLNHQCVVFRYPSGKPFHWQFAKELEIAVAGNI
                     ILDDVDAELEAVLMGAGIGYLLYEQIKEYLDTGRLECVLEDWSTERPGFQIYYPNRQY
                     MSCGLRAFLDYVKTGQICQSQRHRPQ"
     gene            34420..35010
                     /locus_tag="RN951_002228"
     CDS             34420..35010
                     /locus_tag="RN951_002228"
                     /EC_number="1.6.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H oxidoreductase"
                     /protein_id="HDX2527219.1"
                     /translation="MQSERIYLVWAHPRHDSLTAHIADAIHQRAMERKIQVTELDLYR
                     RNFNPVMTPEDEPDWKNMDKRYSPEVHQLYSELLEHDTLVVVFPLWWYSFPAMLKGYI
                     DRVWNNGLAYGDGHKLPFNKVRWVALVGGDKESFVQMGWEKNISDYLKNMCSYLGIED
                     ADVTFLCNTVVFDGEELHASYYQSLLSQVRDMVDAL"
     gene            complement(35092..35832)
                     /gene="pflA"
                     /locus_tag="RN951_002229"
     CDS             complement(35092..35832)
                     /gene="pflA"
                     /locus_tag="RN951_002229"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase 1-activating protein"
                     /protein_id="HDX2527220.1"
                     /translation="MSVIGRIHSFESCGTVDGPGIRFITFFQGCLMRCLYCHNRDTWD
                     THGGKEVTVEDLMKEVVTYRHFMNASGGGVTASGGEAILQAEFVRDWFRACKKEGIHT
                     CLDTNGFVRRYDPVIDELLEVTDLVMLDLKQMNDEIHQNLVGVSNHRTLEFAKYLANK
                     NVKVWIRYVVVPGWSDDDDSAHRLGEFTRDMGNVEKIELLPYHELGKHKWVAMGEEYK
                     LDGVKPPKKETMERVKGILEQYGHKVMF"
     gene            complement(36024..38306)
                     /gene="pflB"
                     /locus_tag="RN951_002230"
     CDS             complement(36024..38306)
                     /gene="pflB"
                     /locus_tag="RN951_002230"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDX2527221.1"
                     /translation="MSELNEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFL
                     AGATEATTTLWDKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQT
                     EAPLKRALIPFGGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRC
                     RKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTI
                     RLREEIAEQHRALSQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMS
                     FGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIW
                     ATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVS
                     IDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGG
                     VDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYE
                     ASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQ
                     FGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGR
                     RAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVR
                     KTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRF
                     NSLTKEQQQDVITRTFTQSM"
     gene            complement(38361..39218)
                     /gene="focA"
                     /locus_tag="RN951_002231"
     CDS             complement(38361..39218)
                     /gene="focA"
                     /locus_tag="RN951_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate transporter FocA"
                     /protein_id="HDX2527222.1"
                     /translation="MKADNPFDLLLPAAMAKVAEEAGVYKATKHPLKTFYLAITAGVF
                     ISIAFVFYITATTGTGTMPFGMAKLVGGICFSLGLILCVVCGADLFTSTVLIVVAKAS
                     GRITWGQLAKNWLNVYFGNLVGALLFVLLMWLSGEYMTANGQWGLNVLQTADHKVHHT
                     FIEAVCLGILANLMVCLAVWMSYSGRSLMDKAFIMVLPVAMFVASGFEHSIANMFMIP
                     MGIVIRDFASPEFWTAVGSAPENFSHLTVMNFITDNLIPVTIGNIIGGGLLVGLTYWV
                     IYLRENDHH"
BASE COUNT         9764 a         9581 c        10407 g         9579 t
ORIGIN      
        1 aatatgttgc ttagctcatg aaaggagcgc aacaagatga tgaatcaaca tataacaaca
       61 tcttaaaaaa aggcctgaca ttacgccagg ccttctgcgt taattaatca cgcttttcca
      121 gcagggtccg gtaaatcaga ccaccgataa tgccgccgac aattggcacc acccagaaga
      181 accacagttg ttctaatgcc cagccgccct ggaagatagc aaccgcggtg ctgcgcgccg
      241 ggttaacaga agtgttagtc accggaatac taattaagtg aatcagggtt aaggccagac
      301 caatagcgat cggcgcaaaa cctgccggcg cgaatttgtc ggttgcgccg tggatcacca
      361 acaggaaacc tgcactcaat accagttcaa ctaccagcgc ggaaagcatg gaataaccgc
      421 ctggtgaatg ctcgccataa ccgttagaag caaaaccgct ggctgccgcg tcaaaacccg
      481 ttttaccact ggcaattaaa tacagcagcg ccgctgcaac aataccgccg acaacctggg
      541 caattacgta gccaacgact tcttttgccg gaaaacgtcc gccagcccat aaaccaatag
      601 tgaccgccgg gttaaaatga ccaccagaaa tatgaccaac agcaaaggcc atcgtcagaa
      661 cggtcagacc gaacgccaac gccacgccgg caaaaccaat gcctaattcc gggaagcctg
      721 cggccagtac agcactacca cagccaccaa aaacaagcca gaaagtacca aaacattcag
      781 ctgctaattt tctgaacata tccacctcaa ttaaaaattg accctgtgaa aaatatggtc
      841 gttttatagg gtcgtcgtaa aaaagtgacg acggaaataa tgcgcggcta ttttaaaaac
      901 gaaggcgagt cattcaccag ataaataaat ccagtaaatt tgatttaggg caacagcggg
      961 ttgccccata tagtcatttg tctgattgac agtgtagtgc acgcaaaaga tttaatcctt
     1021 taggcgtaat aaaaaataat ttatcatgct aattatttga ttttgttgtt tttgcagact
     1081 tatcagcaag agggagtata acgcgattat tcgctcattt ttcagacatt tgccatgctt
     1141 aaatgtgatg tcatcacgta ttagcaaggc ctttcccgtt atactgccag cgtaaaggat
     1201 aagtcacata tttctggagg ggatatgatt cttgagcgcg ttgaaattgt gggttttcgc
     1261 ggtatcaacc gtttgtcgtt gatgctggaa caaaacaacg tcctgattgg ggagaacgcg
     1321 tggggtaaat ccagcttgct ggacgcctta actctgctgc tatcgccaga atcagatctc
     1381 taccattttg agcgcgacga tttctggtac ccgccgggag atatcaacgg gcgagaacat
     1441 catctgcata ttattttgac cttccgcgaa tcgctgccag gccgacatcg ggttcgccgt
     1501 tatcggccgc tggaagcgtg ctggacgcca tgcaccgatg gctatcaccg tattttttat
     1561 cgtctggaag gggagagtgc ggaagacggc agcgtgatga cactgcgcag ttttctcgat
     1621 aaagacggac atccgattga tgtcgaggat attaacgatc aggcacgcca tctggtgcgt
     1681 ttaatgccgg tgctgcgctt gcgtgatgcc cgttttatgc gccgtattcg taacggcacg
     1741 gtgccaaatg tccctaatgt ggaagtcacc gcgcgccagc tcgatttcct cgcccgtgag
     1801 ttatcctcac atccgcaaaa tctctctgat gggcagattc gtcagggact ttccgcaatg
     1861 gtacagctgc ttgagcatta tttctctgag cagggggccg gacaggcgcg atatcgttta
     1921 atgcggcggc gagccagcaa tgagcaacga agctggcgct atctggatat catcaaccgg
     1981 atgattgacc gacctggtgg gcgctcgtat cgggttattt tgctcggcct atttgctact
     2041 ttgttgcagg caaaaggcac attgcgactg gataaagacg cccgtccatt gttgctgatc
     2101 gaagatccag aaacccgttt acaccccatt atgctttcag ttgcctggca tctgttgaat
     2161 cttctgccat tgcagcgcat tgccaccacc aactcgggtg agttgctttc gttaacgccg
     2221 gtagagcatg tttgccgact ggtacgtgag tcctcgcgcg ttgccgcctg gcgtctgggg
     2281 ccgagtggct tgagtaccga agatagccga cgcatatcct ttcacattcg ttttaaccgt
     2341 ccgtcatcgc tgtttgcacg ctgctggttg ctggtggaag gggaaacgga aacctgggtt
     2401 atcaatgaac tggcgcgtca gtgcggacat cattttgatg ccgaagggat caaggtcatt
     2461 gagtttgccc agtccgggct aaagccactg gttaaatttg cccgccgaat ggggattgaa
     2521 tggcatgtac tggtcgatgg cgatgaagca gggaagaaat atgccgctac ggtacgcagc
     2581 ctgttgaata acgatcggga agccgaacga gaacatttaa cggcgttacc ggcgctggat
     2641 atggaacatt ttatgtatcg ccagggattt tccgatgtgt tccaccgcat ggcgcaaatc
     2701 ccggaaaatg taccgatgaa tctacgcaaa attatctcga aagcgatcca tcgctcttcc
     2761 aaacccgatc ttgccattga agtggcaatg gaggcaggac gtcgtggtgt ggactccgta
     2821 ccgacgctgc tgaaaaaaat gttctcacgc gtgctgtggc tggcgcgcgg tcgcgcggat
     2881 taaccgcgaa acatcgtggc catttgtggc tgaatagcgt cgagcatctc atagcgccga
     2941 cggtattcag cccgtttttt actggcgatt tcggcaatct cttttcgtgc tatctgtgct
     3001 ggaaggcggt aatggcgttc agcatcacat acgccgccaa ccgattccca gaaagcgttg
     3061 taatcagcgt ggatcttgcc ttctttatcg cgataacgca ggctgcggta aatatgcgtt
     3121 tcattgctga cggcaataat ctgctctacc tgcaaacgtt gggcaaacag acaggccgct
     3181 tccatcacga ggcgtttggg aaatagcccg tggcaggctt tcgtcgcatt ctggatttcc
     3241 tgatgtggaa tttcccattt tgcgccttgc agtccgccaa taaacatcgt tcttttcccc
     3301 tgatattcac acagggtaaa cgtgatctct gccagaggaa taccttcgct gttgcggaac
     3361 aggattgtgc tgtcaccttc tttatccatt gagatcatca tggtcagctc aagcgtgaac
     3421 tgctcgccgt ttttgccttc cagcttcgcc agttgcagcc cgggggtatt caaatataag
     3481 ctgaattctt ccgccgacat acattcgcgg agtaacgcat aatggtaacg taacgcctcc
     3541 agcaattgct tacggctaag attcgccgca aggtaagggc gatgcagacg cacaggcagt
     3601 cgcggctggc gcgttaacaa tacattgaga ttaggccagt gggaaagttc gttcatccac
     3661 tcaacgctta aacgcggcat aatcaacgag cgcagcaaaa atttctggcg aaaactacgg
     3721 cgatgccaga atttacccgg ccgacactgt ccacgtgcca gactaagaaa aagtgacagg
     3781 ctgctgagag attcagatgg cgtaaaggtc cgttcagtta gctgcgacat attcatgaaa
     3841 tcaatggtta tacatggcgt cgatttcacc attgcgtatc ttaaccaaac atcaatagtg
     3901 tgattactaa cgtaaatttt agggttttgt tgatatttcg ttgaagttaa tgacccggat
     3961 tggcatatgg agtattcaga aaatttatga aaaagcggaa aaccgtgaag aagcgttacg
     4021 ttattgcgct ggtgatagtc atcgccggac tgattacgtt atggagaatt cttaacgcac
     4081 ccgtgccgac ttatcagacg ctgattgtgc gccccggtga tttacagcaa agcgtgctgg
     4141 cgaccggaaa gctggacgcg ctgcgtaagg ttgatgtggg cgcgcaggtc agcggtcagt
     4201 tgaaaactct gtcggtggcg attggcgata aagtaaaaaa agaccagctt ttaggggtta
     4261 ttgatcctga acaggctgaa aaccagatta aggaggtcga agcaacgctg atggagctac
     4321 gtgcgcagcg gcagcaggcg gaagcggagc tgaaactggc gcgggtgacg tattcccgtc
     4381 agcaacgtct ggcacaaacg aaggctgttt cacagcagga tctcgacacc gccgcgacgg
     4441 agatggctgt gaaacaggcg caaattggca ccattgacgc gcaaatcaag cgcaatcagg
     4501 cttctctcga tacggctaaa accaatctcg attacactcg catcgttgcc ccgatggccg
     4561 gggaagtcac gcaaatcacc actctgcaag gccagacggt gattgccgca caacaagcac
     4621 cgaacattct gacgctggca gatatgagca ccatgctggt aaaagcgcag gtttctgaag
     4681 cggatgtaat ccacctgaag ccggggcaaa aagcctggtt tacggtgctt ggcgatccac
     4741 tgacgcgcta cgaggggcaa atcaaggatg tactaccgac gccggaaaag gttaacgacg
     4801 ctattttcta ttacgcccgt tttgaagtcc ccaaccccaa tggtttgctg cggctggata
     4861 tgactgcgca agtgcatatt cagctcaccg atgtgaaaaa tgtgctgacg atccctctgt
     4921 cggcgttagg cgatccggtt ggcgataatc gttataaagt caaattgttg cgtaatggtg
     4981 aaacacgcga gcgtgaagtg acgattggcg cacgtaacga taccgatgtt gagattgtca
     5041 aagggcttga agcgggcgat gaagtggtga ttggtgaggc caaaccagga gctgcacaat
     5101 gacgcctttg ctcgaattaa aggatattcg tcgcagctat cctgccggtg atgagcaggt
     5161 tgaggtgctg aagggcatca gcctcgatat ttatgcgggt gagatggtcg cgattgttgg
     5221 cgcttcgggt tccggtaaat cgaccctgat gaatattctc ggctgtctgg ataaggccac
     5281 cagcggcacc tatcgcgtcg ccggtcagga tgttgccacg ctggacgccg atgcgctggc
     5341 gcaactgcgc cgcgagcatt tcggctttat tttccagcgt taccatttgc tttcgcattt
     5401 aaccgccgag cagaacgttg aagtacccgc cgtctatgct ggtcttgagc ggaaacagcg
     5461 actgcttcgt gcccaggagt tgctgcaacg gctggggctg gaagaccgta cagagtatta
     5521 tccggcacag ctttcgggtg gtcagcaaca gcgcgtcagc atcgcgcggg cattgatgaa
     5581 cggtggtcag gtaattcttg ccgatgaacc aaccggcgca ctggacagcc attctggcga
     5641 agaggtgatg gcgatcctgc atcagctgcg cgatcgtggg catacggtga ttatcgtcac
     5701 ccacgatccg caggtcgctg ctcaggccga gcgggtgatc gaaattcgcg acggcgaaat
     5761 tgtgcgcaat cctcccgcca ttgaaaaagt gaatgttact ggcgggacgg aacctgttgt
     5821 caacacggtg tctggctggc ggcagtttgt cagcggtttt aacgaggcgc tgacgatggc
     5881 atggcgggcg ctggcagcga ataaaatgcg tactttactg accatgctgg ggattattat
     5941 cggtattgcg tcggtggttt ccattgtcgt ggtgggtgac gccgccaaac aaatggtgct
     6001 ggcggatatt cgttctattg gtacgaatac tattgatgtc tatcccggga aagattttgg
     6061 cgatgacgat ccgcaatatc agcaggcgct gaagtacgac gacttaatcg ccatccaaaa
     6121 acaaccgtgg gtcgcctcag ccacacctgc cgtctcgcaa aacctgcgcc tgcgttataa
     6181 caatgttgat gttgctgcca gtgccaatgg cgtgagcggc gattatttta atgtctatgg
     6241 catgaccttc agtgaaggaa acacctttaa tcaggagcag ctgaacggtc gtgcgcaggt
     6301 cgtggttctc gacagtaata ctcgccgcca gcttttcccc cataaagcag atgtggttgg
     6361 cgaggtgatt ctggtcggca atatgcccgc cagagtcatt ggtgtggcgg aagaaaaaca
     6421 gtcgatgttt ggtagcagta aagtgctgcg tgtctggcta ccttacagca cgatgtccgg
     6481 gcgagttatg ggccagtcgt ggcttaactc cattactgtc agggtgaaag aaggatttga
     6541 cagcgccgag gcggaacagc aactcacgcg tttactttca ctgcgccacg gaaagaagga
     6601 tttctttacc tggaacatgg acggcgtctt gaaaactgtt gaaaagacca cacgtacttt
     6661 acaactgttt ctgacgctgg tggcggtgat ttcgctggtg gtgggcggta ttggtgtaat
     6721 gaatattatg ctggtgtcag tgaccgagcg gacgcgggaa attggcattc gcatggctgt
     6781 aggtgcgcga gcaagcgatg ttttgcaaca gttcctgatc gaagccgtac tggtttgcct
     6841 ggtcggtggc gcgttgggaa taacactgtc actgttaatt gctttcacct tgcagctttt
     6901 cttacccggc tgggagattg gtttttcacc gttggcgctg ctgctggcgt ttctctgctc
     6961 gacggtcacc gggattttat ttggctggtt acccgcacga aatgcggcac gactggatcc
     7021 agtagatgct ctggcacgag agtaattttt gagataaaaa tgccagccga tcgggctggc
     7081 attttgcctt taggatgtac acaatgagac agaagagcta tgcgactgcc gcttctactt
     7141 cgacgggcac aataacactg gcgtgattgc cttttggccc ctggtggaca tcaaactgaa
     7201 cggattgtcc agcttttagc gttctgtaac catccatctg aatggtggaa taatgagcga
     7261 aaatatcttc gccgccgcct tcagggcaga tgaaaccaaa ccctttggca ttgttgaacc
     7321 acttaacagt acccttttcc atgcttcgac atccttcgca aatcttatac aagtaagatg
     7381 gaataaaccg gggtcagaga gggggctgtt caaaacctcg ccaactctag aaatacaatt
     7441 tagagaatta gggcgagccg tcaagcattt gacaggggac aaggggcagg tatgaatcaa
     7501 aaatttgaag cagttaacgc tattgacagg aatgtgacag atgtcgctga tgccaacgat
     7561 agatgatagt tatctatcat gtggagtaga ttggtcaggc aaataagctc ttgtcagcgg
     7621 cagggcgttc tgccgataac cgtaaccgaa gatgataact gacaatgggt aaaacgaacg
     7681 actggctgga ctttgatcaa ctggcggaag aaaaagttcg cgacgcgcta aaaccgccat
     7741 ctatgtataa agtgatatta gtcaatgatg attacactcc gatggagttt gttattgacg
     7801 tgttacaaaa attcttttct tatgatgtag aacgtgcaac gcaattgatg ctcgctgttc
     7861 actaccaggg gaaggccatt tgcggagtct ttaccgccga ggttgcagaa accaaagtgg
     7921 cgatggtgaa caagtacgcg agggagaatg agcatccatt gctgtgtacg ctagaaaaag
     7981 cctgaatgca ggcataaaaa ttgggggagg tgcctatgct caatcaagaa ctggaactca
     8041 gtttaaatat ggctttcgcc agagcgcgcg agcaccgtca tgagtttatg accgtcgagc
     8101 acttgttact ggcgctgctc agtaacccat ctgcccggga ggcgctggaa gcgtgttctg
     8161 tggatttggt tgcgctccgt caggaactgg aagcctttat tgaacaaacc acacccgttc
     8221 tgcctgccag tgaagaggag cgcgacacac agccgacgct gagttttcag cgtgtactgc
     8281 aacgtgcggt cttccatgtc cagtcctccg gtcgcaatga ggttaccggt gcaaacgttc
     8341 tggtcgctat ctttagcgaa caggagtcgc aggcggcata tctgttgcgt aaacatgaag
     8401 tcagccgtct cgatgtggtg aactttatct ctcatggcac gcgtaaagac gagccgacac
     8461 agtcttctga tcctggcagc cagccaaaca gcgaagaaca agctggtggg gaggaacgta
     8521 tggagaattt cacgacgaac ctgaatcagc ttgcgcgcgt gggcggaatc gacccactga
     8581 ttggtcgtga gaaggagctg gagcgtgcta ttcaggttct ctgccgtcgc cgtaaaaaca
     8641 acccgctgct ggtgggggaa tctggtgtcg gtaaaaccgc gattgcggaa ggtcttgcct
     8701 ggcgaattgt tcagggcgat gtgccggaag tgatggctga ctgtacgatt tactctctcg
     8761 atatcggttc tctgttagcg ggcacaaaat atcgcggcga ctttgaaaaa cgttttaaag
     8821 cgttgctcaa gcagctggag caggacacta acagcatcct gtttattgat gagatccaca
     8881 ccattatcgg tgcgggtgca gcgtctggtg gtcaggtcga tgcggctaac ctaatcaaac
     8941 cgttgctctc cagcggtaaa attcgtgtaa ttggttcgac aacctatcag gagttcagca
     9001 acattttcga gaaagaccgt gctctggcgc gtcgcttcca gaaaattgat attactgaac
     9061 cgtcgatcga agaaactgtt caaatcatca atggcctgaa accgaagtat gaagcgcacc
     9121 acgacgtgcg ttataccgca aaagcggtgc gtgcggcggt agagctggcg gtgaaataca
     9181 ttaacgatcg tcatctgccg gataaagcca ttgatgttat cgacgaagcg ggcgctcgcg
     9241 cacgcctgat gccggtaagc aaacgcaaga aaaccgttaa tgtggcggat attgagtccg
     9301 tggtggcccg tattgcacgc attccagaga agagtgtttc tcagagtgat cgtgataccc
     9361 tgaaaaacct cggcgatcgc ttgaaaatgc tggtcttcgg tcaggataaa gccattgagg
     9421 cgctgactga agccattaag atggcgcgtg caggtttagg tcacgaacat aaaccggttg
     9481 gttcgttcct gtttgccggc cctaccgggg tcgggaaaac agaggtgacg gtacagcttt
     9541 cgaaagcttt gggcattgag cttctgcgct ttgatatgtc cgagtatatg gaacgccata
     9601 ccgtcagccg tcttattggt gcgcctccgg gatacgttgg ttttgatcag ggcggtttgc
     9661 tgactgatgc ggtcatcaag catccacatg cggtgctgct gctggacgaa atcgagaaag
     9721 cgcacccgga cgtgttcaat attctgttgc aggtgatgga taacggtacg ctgaccgata
     9781 acaacggacg caaagcagac ttccgtaacg tggtgctggt gatgaccacc aacgccgggg
     9841 tacgggaaac tgagcgcaaa tccattggtc ttatccacca ggataacagc accgatgcga
     9901 tggaagagat caagaagatc tttacaccgg aattccgtaa ccgtctcgac aacattatct
     9961 ggtttgatca tctgtcaacc gacgtgatcc atcaggtggt ggataaattc atcgtcgagt
    10021 tgcaggttca gctggatcag aaaggtgttt ctctggaagt gagccaggaa gcgcgtaact
    10081 ggctggccga gaaaggttac gaccgggcaa tgggcgctcg tccgatggcg cgtgtcatcc
    10141 aggacaacct gaaaaaaccg ctcgccaacg aactgctgtt tggttcgctg gtggacggcg
    10201 gtcaggtcac cgtcgcgctg gataaagaga aaaatgagct gacttacgga ttccagagtg
    10261 cacaaaagca caaggcggaa gcagcgcatt aatctgattg ttaggtaggt tggtcaagtc
    10321 cgtaatctcg aaagaggtta cggacttttt gtttatgggg tggaggaggt tcagaccctt
    10381 tttttaatga tgatggtaag ttgttgataa ttagtgctgc gggaaggtaa ggataaaaaa
    10441 gggtgctgca ggagaatggg atggttttgc tttattaaca acgggctaaa cgtgtagtat
    10501 ttgagttcac tgccgtacag gcagcttaga aattcacagg taacatactc cacccgccca
    10561 ccatgttcac tgccgtacag acagataaaa tgcgaaaaaa aagctcgcac tttcgtacga
    10621 gctcttcttt aaatatggcg gtgagggggg gattcgaacc cccgatacgt tgccgtatac
    10681 acactttcca ggcgtgctcc ttcagccact cggacacctc accaaattgt tttgctacca
    10741 aacctcatgg gtggcaacgg ggcgctacta tagggagttg gagtaaaacg gtcaagaaga
    10801 attttaatga taattattgt ttgctcatac tgtaaacaag ttgtgcagta tatctacatc
    10861 gagacaagtt acggacttat acttccaaag tacttcatac atatcacaaa ataaaaaggc
    10921 cggttaaacc gaccttttac tcgttctttc tcttcgccca tcaggcggta aaacaatcag
    10981 cgactacgga agacaatgcg gcctttgctc aggtcgtacg gggtcagttc aacagtcact
    11041 ttgtcgcccg tcaggatgcg gatgtagttt ttgcgcattt taccggagat gtgtgcagta
    11101 accacgtgac cgttttctaa ctctacgcgg aacatggtat taggcaacgt ttcaagaacg
    11161 gtaccttgca tttcaatatt gtcttctttg gccatctaat cctctggggt atcactaccg
    11221 taatttgaac cggcaagata atgccgaagt tctgtaaata agtaaagatt tgcgcgctaa
    11281 atcgcaacaa acaggttcgg cacattactc cgaaaacaca cggctaagcc gcaccaaaag
    11341 cgcaacgtat aagggagcgg tgagataaac gatgggcgtt acctgacgcg aaaaattcct
    11401 tatcggcagc ggggtaatga gcgtaaccaa ctctgcgacc gcaattataa cactctgggg
    11461 agaaatgtgc cgaaaacatt cattcttgtg gtgaaaacaa gcatcgtggt acccagaaat
    11521 tattcggcaa tcgtccgagg cgcatttgat tgagataatt aaggtaatcc cggcggggaa
    11581 tttcgcaggc accaagcgat gctgtgtgat cgttaaggac ctggcagtcg ataagcttac
    11641 cgccatgacc gataaattcc tcacagaata ccagaagcgc cgttttagac gcattttcca
    11701 tccggctgaa catggactcg ccacaaaata gcgttccctg ggccacgccg tacataccgc
    11761 cgacaagctc atcttcacgc cagacttcaa tggagtgggc atggccgagt tcgtgaaggc
    11821 gatggtaggc ttcgaccacg ccacgcgtga tccaggttcc ttcttcgcga tcgctggcac
    11881 agccttcaat gacctgacca aaagcgtaat tcatcgtgac acgatagggc gagcgtttat
    11941 gaaatcgctt catactacgg ctgatatgca gtgattctgg ccatagcacc gcgcggggat
    12001 cgggcgacca ccagaggatg gggtcgcctg gagaaaacca cggaaaaata ccacgctggt
    12061 aagccattaa caggcgcgca gggctaagat cgcccccaag tgccagcagg ccgttaggct
    12121 cacgtaatgc gccttccggg gaagggaagg ctattgaatg gcgagaaagc tgaaccaggc
    12181 gcatgaccgc aaaactccac gcaagtcgga tcgttcaata atagcttaca aaccctgctt
    12241 gaactggtaa taacgcccct gtctggcaag cagttctgcg tgagtacctt gctcaataat
    12301 ttgcccgttg tccatcacta ttatttgttg gaaacgagag agtccgcgaa gtcgatgggt
    12361 gaccattaac accgttttct cacgcatcat ttctgcaagc aattcaagga tctggctttc
    12421 ggttgtggca tctaagcctt cggtaggttc atccagcaac accagtggcg catcatgtaa
    12481 cagcgcacgg gcgatagcca gacggcgcag ttcaccaccg gagagctggc gtccgccttc
    12541 acctaaccaa ctgttgagac ctgcatcctc gagcagcttt tccaggccaa cgcgacgcaa
    12601 gatctccgac agagcctcat cactactgcc aggcgaggcg agtaaaagat tatcacgcag
    12661 cgtggcgcta aacagatgca ctcgctgagg aacaacgctg atggtctgtc gtagagccgc
    12721 ttcattcagg ctggctatgg ggctatcgtt aagcaaaatc tcgccctgtt gcgggtccca
    12781 tgcgcgggtc agcagttgta acagtgttga tttgccgcat ccggttcgcc cgagaatcgc
    12841 tatatgttcc ccggcgttta cctgaagaga aatcccttta agtgcctgtt gagattgctc
    12901 cggataagtg aactgaacat cccgtaacgt cagcgaaacg cgatcggcaa cacgagtttg
    12961 ggtatcagga aaggtgacct ccggtttttg atccgttaag tcagagatac gtacggcaga
    13021 ggcaatgact tgccccagat gctgaaatgc acccgttact ggtgccagtg cttcaaacgc
    13081 ggctaacgcg cagaagacaa acagggcaat taacgcgccg ggttgagcat tgccgccaac
    13141 gccgccagac gccatccaca gcatcaggat caccgctaac gcgccaatga gcagcattat
    13201 cgcttgcgac aatgcggtca gttcagattg acggcgttgc gcttccagcc attgaatttc
    13261 tgtattctct agttgcgtgc gataacgatc gctggcacca aaaatggtca gctcagcttg
    13321 cccttgcagc caggccgtca gttgttggcg atactgtccg cgaagatgag tcagattttg
    13381 cccggtgctt tttcccgcac gataaaacag cggtggcatc aggaaaagcg tcagtaacat
    13441 aatgccgccc agcgtaaagg cgagggtgaa atcaaggaaa cttaacccga ttgtcaccac
    13501 cataatcacc acaaaagcgc ccaccagcgg cgagataacg cgcaggtaaa gatgatcgag
    13561 cgtatcaaca tccgccacca cgcgattgag caattcgccc tgacgatagc gcgccagtcc
    13621 ggcaggggag aggggcagca atttgctgaa ggtgtaaatg cgcagatgct gcaacacgcg
    13681 gaaagtcgcg tcgtgactta ccagacgttc aaaatagcgc ccggcagtac gggtgattgc
    13741 tgcgccacgc acgcccgcag cgggtagcat atagttgaag ctgtacagtc cggcaacccc
    13801 cgcaaccgct gaggccgaga ggaaccagcc ggaaagtgtc aacagaccga tactggcgag
    13861 cagcgtcaca attgccagca caataccaag acttaacatc catttatgac gtttatacag
    13921 tgccagatag ggtagcaaag cgcgcattta aatctcctcc tgacgatggg ccagtaatgt
    13981 ggcgaatggg ccaccagcca cacttaattc cgcgtaacgt ccttgctcaa taatccggcc
    14041 atcctgcata acccaaatga catcccagtc agcaagatct tctaactggt gggtgaccat
    14101 taacgttgtc tggcgcagag aggcggcatt cagcgcctcc attacgcgct gttcactgtg
    14161 agcatcaagg ctggcagcgg gttcatccaa cagtaatagc gaacagggat ttagtaacgc
    14221 acgggccacc gccacgcgct gcgcctgccc cacggaaagg cgggcagcct ggtcgccaac
    14281 aggcgtatca acgccttgtg ggaggagcgg tagaaactcg ctgacccagg cgttatccag
    14341 cgctgcttgt aattcttgtt cgctggcatc aggtcgcgcc agtagtacgt tatcccgcaa
    14401 tgttgctgcc ggtaattgtg ggttttgccc aacccaggag agatgtttac gccatgattc
    14461 tggtgataaa tcgcgtaatt ctatcccgtt gattcgtagc gatccctgat atgagaaaaa
    14521 accagaaagc gcgttcagca gtgagctttt acctgaaccg ctgcgaccaa ccaacaccgc
    14581 acgttggcct gctggcaaag taaagttcag cggtccggcc agcgttttac cttccggcga
    14641 cgtgataaac agctcctcgg cctcaatggt caccggatcg gtcgatgcta attccgcctc
    14701 accacgttgc ggatgggcga gcggggtttc cataaacgtt ttcagactgt cagctgcgcc
    14761 aacagcctgg gctttagcat gataaaacgt accgagatcg cgtaatggct ggaaaaactc
    14821 tggcgcaagg atcagggcca gaaaacccgc agccagcgtc acaccggtat cgtagtgacc
    14881 aaaatccagc tcgccgagat aggaaaaacc aaagtagacc gccaccagag caattgacag
    14941 cgaggtaaaa aattcgagaa tgccggagga taaaaacgcc agccgtagca cttccattgt
    15001 ccgttggcgg aaatcttccg aagcagaacg aatactttca atttcagctt caccacgacc
    15061 aaaaatacgc aatgtttcca tgccgcgcag gcgatcgagg aaatgcccac ttaagcgagc
    15121 aagagcgaga aagttacgtc ggttagcatc ggcagccccc attccaacca gcgccataaa
    15181 caacggaatt aacggtgcag tgcccagcag aatgagcgcc gcagcccagt tagaggggaa
    15241 gattgccacc acaatcagca acggcaccga cactgccagc gccatttgcg gcagatagcg
    15301 tgcatagtaa tcatgcatat cgtcaatttg ctcgagtacc agcgtcgccc agctccccgc
    15361 aggtttaccc tgaatccacg ctggccctgc ttgttgcaga cggtcgagaa cctgacggcg
    15421 gatggcaaag cggatatgct gcccggcgtg ataacccacc cgttcgcgta accagaccac
    15481 ccatgcgcgc agtacaaagg tcagaaccag taacgtaaag ggaagcagca gggcttcacg
    15541 gggaatattc tccataatca tatgttgcag aattcgcgcc atgaaccagg cctgggcaat
    15601 gatcaatatg ccgctcacaa agcccagcag acgagaaata ttcagccaac gttgggagat
    15661 gacgctttgc tgttttaacc agcgggttaa ctctttttga cgagatttat tcattgcacg
    15721 cttagcaggt gagttatcag aattatttgc agagcaatgt tacaacgggg aaaaaataaa
    15781 ggcgacccat agtcgcatgg tgtcgccttc tttacttttg ttactgattt gtaaaattat
    15841 tttgcgtcag ctaaaccatc gaggtagcgt tccgcatcaa gtgctgccat gcagcctgta
    15901 ccggccgaag taatggcctg gcgataaatg tgatccatca cgtcgcctgc ggcaaagacg
    15961 ccaggaatgc tggtctgggt ggcattacca tgaatacccg actgtacttt gatgtagccg
    16021 ttttccagtt ccagctgccc ttcgaaaatc gcagtattcg ggctgtgacc gatagcaaca
    16081 aacagaccgg caacgtcgag tgactcgatg ttatcgctgt tttgcgtatc gcgcagacga
    16141 acgccagtga cacccatttg atcgccggtc acttcttcca gcgtacggtt ggtgtgcaga
    16201 atgatgttgc cgttctccac tttatccatc aggcgcttaa tgaggatttt ttccgcgcgg
    16261 aaaccgtcac ggcggtgaat cagatgcact tccgaagcga tgttagacag atacagcgcc
    16321 tcttcaaccg cggtattgcc gccgccgatg accgcaactt tctggttgcg atagaagaaa
    16381 ccgtcgcagg ttgcacaagc agaaacccca cggcctttaa aggcttcttc agagggcagg
    16441 ccgagatagc gtgcagaagc tccggtggca ataatcagcg cgtcgcaagt gtattcgccg
    16501 ttatcgccat tcagacggaa cggacggttt tgcagatcca ccttgttgat atgatcaaaa
    16561 atgatctcag tttcaaactt ggtggcatgt tcgtgcatgc gctccattaa taacggaccg
    16621 gtcagatcgt ttggatcgcc aggccagttt tccacttccg tggtggtggt cagttggccg
    16681 cctttttcca tgccggtaat cagcacaggt tgcaggttgg cgcgcgccgc gtagacagca
    16741 gcggtgtatc ccgccgggcc tgaacccagg ataagcagtt tactgtgttt ggtcgtgccc
    16801 atgagatccc catagttgtt ggcagacaat gggcaggatt gtagggaatt tacagacgta
    16861 aaaaaagagt atgacgattt tgttaacaat ttgtgcaatc ggcagcatcg ataagcaggt
    16921 caaattctcc cgtcattatc acctctgcta cttaaatttc ccgctttata agccgattaa
    16981 atgatgaata aacgcccctg ttaatgaata tctggcatgt tgtactaaaa atcgatgttt
    17041 tgctttgaca atcccctggt gttttgcgaa aacattcgag gaagaaaaaa aacagtattc
    17101 ttatatgcgc ataaccatgc atgtaaatac catgtttacc gtgctagtga aatctacgta
    17161 tggcgtggac agacgccatt cgtgatgtcg atagctgcca caaggcaacg gtcttctcac
    17221 cgtagaccca ggcattgcgc gccgtgaatc ttcatgattt cggtctatcg tgacgggtag
    17281 cgactctgaa cagtgatgtt tcagggtcag acaggagtag ggaaggaata cagagagaca
    17341 ataataatgg tagatagcaa gaagcgccct ggcaaagatc tcgaccgtat cgatcgtaac
    17401 attcttaatg agttgcaaaa ggatgggcgt atttctaacg tcgagctttc taaacgtgtg
    17461 ggactttccc caacgccgtg ccttgagcgt gtgcgtcggc tggaaagaca agggtttatt
    17521 cagggctata cggcgctgct taacccccat tatctggatg catcacttct ggtattcgtt
    17581 gagattactc tgaatcgtgg cgcaccggat gtgtttgaac aattcaatac cgctgtacaa
    17641 aaacttgaag aaattcagga gtgtcattta gtatccggtg atttcgacta cctgttgaaa
    17701 acacgcgtgc cggatatgtc agcctaccgt aagttgctgg gggaaaccct gctgcgtctg
    17761 cctggcgtca atgacacacg gacatacgtt gttatggaag aagtcaagca gagtaatcgt
    17821 ctggttatta agacgcgcta acacggaaca ggtgcaaaat cggcgtattt tgattacact
    17881 cctgttaatc catacagcaa cagtactggg gtaacctggt actgttgtcc gttttagcat
    17941 cgggcaggaa aagcctgtaa cctggagagc ctttcttgag ccaggaatac actgaagaca
    18001 aagaagtcac attgacaaag ttaagtagcg gccgccgcct tctggaggcg ttgctgatcc
    18061 ttattgtcct gtttgccgtc tggttgatgg ctgccttact aagctttaac ccttcggacc
    18121 ccagctggtc gcaaacggcc tggcatgaac ctatccataa tttaggtggg atgcccggtg
    18181 cgtggttggc agatacgctg ttctttattt ttggcgtgat ggcttacacc attcccgtca
    18241 ttattgtcgg cggttgttgg tttgcctggc gtcatcagtc cagcgacgaa tacattgatt
    18301 attttgccgt ttcgctacgc atcattggcg ttttggcgct catccttacc tcctgtggtc
    18361 tggcggcaat caacgctgac gatatctggt attttgcctc cggtggcgtc attggcagct
    18421 tactaagcac tacgctacaa ccactgctac acagtagcgg gggaactatt gcgctgctct
    18481 gcgtttgggc agcgggcctg acgttgttca ccggttggtc atgggtgacc attgctgaaa
    18541 aactcggcgg ctggatttta aacattctta ccttcgccag taatcgtacc cgtcgcgatg
    18601 atacctgggt cgatgaagat gagtatgaag acgacgaaga gtatgaagat gaaaatcacg
    18661 gcaaacagca tgaatcacgc cgtgcccgta ttcttcgcgg cgcgctagcg cgtcgtaaac
    18721 ggttggcgga aaaattcatt aatccgatgg ggcggcaaac agacgctgcg ttgttctccg
    18781 gtaagcggat ggatgatgac gaagagatta cctacactgc acgcggtgtg gctgccgacc
    18841 cggacgacgt cctattttcg ggcaatcgtg caacgcagcc agaatatgac gaatacgatc
    18901 cattattaaa cggtgcgcca attaccgaac ctgtcgctgt agcagctgct gctaccacgg
    18961 cgacacaaag ctgggctgcg ccggttgaac ctgtgactca gacgccgcct gttgcctctg
    19021 ttgatgttcc acctgcgcaa cctacagtag cctggcagcc tgtaccgggt ccacaaacgg
    19081 gagagccggt tattgctcct gcaccggaag gttacccaca gcagtcacaa tatgcgcagc
    19141 ctgcagtgca atataatgag ccgctgcaac aaccagtaca gccgcagcag ccgtattatg
    19201 cacctgcagc tgaacaacct gcgcaacagc cgtattatgc ccctgcgcca gaacaaccgg
    19261 tggcaggtaa cgcctggcaa gccgaagagc agcaatccac ttttgctcca cagtctacat
    19321 accagactga gcaaacttat cagcagccag ccgctcagga gccgttgtac caacagccgc
    19381 aacccgttga acagcagcct gttgtggagc ctgaacccgt tgtagaagag acaaaacccg
    19441 cgcgtccgcc gctttactac tttgaagaag ttgaagagaa gcgagcccgt gaacgtgaac
    19501 aacttgcggc ctggtatcaa ccgattccag aaccggttaa agaaccagaa ccgatcaaat
    19561 cttcgctgaa agcaccttct gttgcagcag tacctccagt agaagccgct gccgctgttt
    19621 ccccgctggc atctggcgtg aaaaaagcga cactggcgac gggggctgcc gcaaccgttg
    19681 ccgcgccagt cttcagtctg gcaaatagcg gtggaccgcg tcctcaggtc aaagagggga
    19741 ttggtccgca gttgccacga ccgaaacgta tccgcgtgcc aactcgtcgt gaactggcgt
    19801 cttacggtat taagctgccc tcacagcgtg cggcggaaga aaaagcccgt gaagcccagc
    19861 gcaatcagta cgattctggc gatcagtaca acgatgatga aatcgatgcg atgcagcagg
    19921 atgaactggc acgtcagttc gcccagacac agcagcaacg ctatggcgaa cagtatcaac
    19981 atgatgtgcc cgtaaacgca gaagatgcag atgctgcggc agaggctgaa ctggctcgtc
    20041 agtttgcgca aactcaacaa caacgttatt ccggcgaaca accggctggg gcgaatccgt
    20101 tctcgctgga tgattttgaa ttttcgccaa tgaaagcgtt gctggatgat ggtccacacg
    20161 aaccgttgtt tacgccaatt gttgaacctg tacagcagcc gcaacaaccg gttgcaccgc
    20221 agcagcaata tcagcagccg caacaaccag ttccgccgca gccgcagtat cagcagccac
    20281 aacagccggt tgcgccgcag ccacaatatc agcagccgca acaaccggtt gcgccacagc
    20341 agcaatatca gcagccgcaa caaccggttg cgccgcagca gcagtatcag cagccacaac
    20401 agccagttgc gccacaaccg caggataccc tgcttcatcc gctgttgatg cgtaatggcg
    20461 acagccgtcc gttgcataaa ccgacgacgc cgctgccttc tctggatttg ctgacaccgc
    20521 cgccgagcga agtggagccg gtagatacct ttgcgcttga acaaatggct cgcctggtgg
    20581 aagcgcgtct ggctgatttc cgtattaaag ccgatgtcgt caattactct ccggggccgg
    20641 ttatcactcg ctttgaattg aacctggcac cgggcgtaaa agcggcgcgc atttctaact
    20701 tgtcacggga ccttgcccgt tcactttcga cggtggcggt gcgtgtcgtt gaagttattc
    20761 ctggcaaacc ctatgtaggt ctggagttac cgaataaaaa acgacaaacc gtttatctgc
    20821 gcgaagtttt ggataacgcc aaattccgcg ataatccgtc gccattaacc gtggtgctgg
    20881 gtaaagatat cgccggtgag ccggtggttg ccgatctggc gaaaatgccg cacttgttgg
    20941 ttgcggggac taccggttcc ggtaaatctg tcggtgtgaa cgcgatgatc ctgagcatgc
    21001 tttataaagc acagccagaa gatgtgcgtt tcatcatgat cgacccgaaa atgctggagc
    21061 tttcggttta tgaaggcatt ccgcatctgt taacggaagt cgttactgat atgaaagatg
    21121 ccgccaacgc gctgcgctgg tgtgttaacg agatggagcg tcggtataaa ctgatgtctg
    21181 cgctgggtgt gcgtaatctg gcgggttata acgaaaaaat tgctgaagcc gatcgcatga
    21241 tgcgtccgat tccagacccg tactggaagc cgggtgacag tatggatgcc cagcatccgg
    21301 tgctgaaaaa agaaccatac attgtggtgt tggttgacga atttgccgac ctgatgatga
    21361 cggtaggtaa aaaagtggaa gagctgatag cacgtctggc gcaaaaagcc cgtgccgcgg
    21421 gtatccacct cgtactggca actcagcgtc catcggttga tgttattact ggtctgatta
    21481 aagcgaatat tccgacccgt atcgccttta ccgtatccag taagattgac tcacgtacca
    21541 ttcttgatca ggctggcgcg gaatcactgc tgggtatggg ggatatgctc tactctgggc
    21601 cgaactccac gttgccggta cgtgtccatg gtgcttttgt tcgcgatcag gaagttcatg
    21661 ccgtggtgca ggactggaaa gcgcgtggtc gcccacagta tgttgatggc atcacctccg
    21721 acagcgaaag cgaaggtggt gcgggtggtt tcgatggcgc tgaagaactg gatccgttgt
    21781 tcgatcaggc ggtgcagttt gtcactgaaa aacgcaaagc gtcaatttct ggcgtacagc
    21841 gtcagttccg cattggttat aaccgtgcag cgcgtattat cgaacagatg gaagcgcagg
    21901 ggattgtcag cgaacagggg cacaacggta atcgtgaagt gctggcccca ccgccgtttg
    21961 actaactaat gcatcgtatg ccggataagg cgcggtagcg tcgcatccgg cactctatca
    22021 actgaaaatt cagtattttc ttctttcctc aagctgatta ttagcctgga atagagagta
    22081 gagggaactc ccgatcggga gtgacgtaat ttgaggaata atgatgaaaa aaattgccat
    22141 cacctgtgca ttactctcaa gcttagtagc aagcagcgtt tgggctgatg ccgcaagcga
    22201 tctgaaaagc cgcctggata aagtcagcag cttccacgcc agcttcacac aaaaagtgac
    22261 tgacggtagc ggcgcggcgg tgcaggaagg tcagggcgat ctgtgggtga aacgtccaaa
    22321 cttattcaac tggcatatga cacaacctga tgaaagcatt ctggtttctg acggtaaaac
    22381 actgtggttc tataacccgt tcgttgagca agctacggca acctggctga aagatgccac
    22441 cggtaatacg ccgtttatgc tgattgcccg caaccagtcc agcgactggc agcagtacaa
    22501 tatcaaacag aatggcgatg actttgtcct gacgccgaaa gccagcaatg gcaatctgaa
    22561 gcagttcacc attaacgtgg gacgtgatgg cacaatccat cagtttagcg cggtggagca
    22621 ggacgatcag cgcagcagtt atcaactgaa atcccagcaa aatggggctg tggatgcagc
    22681 gaaatttacc ttcaccccgc cgcaaggcgt cacggtagat gatcaacgta agtagaggca
    22741 cctgagtgag caatctgtcg ctcgattttt cggataatac ttttcaacct ctggccgcgc
    22801 gtatgcggcc agaaaattta gcacagtata tcggccagca acatttgctg gctgcgggga
    22861 agccgttgcc gcgcgctatc gaagccgggc atttacattc tatgatcctc tgggggccgc
    22921 cgggtaccgg caaaacaact ctcgctgaag tgattgcccg ctatgcgaac gctgatgtgg
    22981 aacgtatttc tgccgtcacc tctggcgtga aagagattcg cgaggcgatc gagcgcgccc
    23041 ggcaaaaccg caatgcaggt cgccgcacta ttctttttgt tgacgaagtt caccgtttca
    23101 acaaaagcca gcaggatgca tttctgccac atattgaaga cggcaccatc acttttattg
    23161 gcgcaaccac tgaaaacccg tcgtttgagc ttaattcggc actgctttcc cgtgcccgtg
    23221 tctatctgtt gaaatccctg agtacagagg atattgagca agtactaact caggcgatgg
    23281 aagacaaaac ccgtggctat ggtggtcagg atattgttct gccagatgaa acacgacgcg
    23341 ccattgctga actggtgaat ggcgacgcgc gccgggcgtt aaatacgctg gaaatgatgg
    23401 cggatatggc cgaagtcgat gatagcggta agcgggtcct gaagcctgaa ttactgaccg
    23461 aaatcgccgg tgaacgtagc gcccgctttg ataacaaagg cgatcgcttt tacgatctga
    23521 tttccgcact gcataagtcg gtacgtggta gcgcacccga tgcggcgctg tactggtatg
    23581 cgcgaattat taccgctggt ggcgatccgt tatatgtcgc gcgtcgctgt ctggcgattg
    23641 cgtctgaaga cgtcggtaat gccgatccac gggcgatgca ggtggcaatt gcggcctggg
    23701 attgctttac tcgcgttggc ccggcggaag gtgaacgcgc cattgctcag gcgattgttt
    23761 acctggcctg cgcgccaaaa agcaacgctg tctacactgc gtttaaagcc gcgctggccg
    23821 atgctcgcga acgcccggat tatgacgtgc cggttcattt gcgtaatgcg ccgacgaaat
    23881 taatgaagga aatgggctac gggcaggaat atcgttacgc tcatgatgaa gcaaacgctt
    23941 atgctgccgg tgaggtttac ttcccgccgg aaatagcaca aacacgctat tatttcccga
    24001 caaacagggg ccttgaaggc aagattggcg aaaagctcgc ctggctggct gaacaggatc
    24061 aaaatagccc cataaaacgc taccgttaat gttatcgttg cggtaatgtt gttactgtat
    24121 ccctgtggtc gcaggctgtg gccacatctc ccatttaatt cgataagcac aggataagca
    24181 tgctcgatcc caatctgctg cgtaatgagc cagacgcagt cgctgaaaaa ctggcacgcc
    24241 ggggctttaa gctggatgta gataagctgg gcgctcttga agagcgtcgt aaagtattgc
    24301 aggtcaaaac ggaaaacctg caagcggagc gtaactcccg atcgaaatcc attggccagg
    24361 cgaaagcgcg cggggaagat atcgagcctt tacgtctgga agtgaacaaa ctgggcgaag
    24421 agctggatgc agcaaaagcc gagctggatg ctttacaggc tgaaattcgc gatatcgcgc
    24481 tgaccatccc taacctgcct gcagatgaag tgccggtagg taaagacgaa aatgacaacg
    24541 ttgaagtcag ccgctggggt accccgcgtg agtttgactt tgaagttcgt gaccacgtga
    24601 cgctgggtga aatgcactct ggcctcgact ttgcagctgc agttaagctg actggttccc
    24661 gctttgtggt aatgaaaggg cagattgctc gcatgcaccg cgcactgtcg cagtttatgc
    24721 tggatctgca taccgaacag catggctaca gtgagaacta tgttccgtac ctggttaacc
    24781 aggacacgct gtacggtacg ggtcaactgc cgaaatttgc tggcgatctg ttccatactc
    24841 gtccgctgga agaagaagca gacaccagta actatgcgct gatcccaacg gcagaagttc
    24901 cgctgactaa cctggtgcgc ggtgaaatca tcgatgaaga tgatctgcca attaagatga
    24961 ccgcccacac cccatgcttc cgttctgaag ccggttcata tggtcgtgac acccgtggtc
    25021 tgatccgtat gcaccagttc gacaaagttg aaatggtgca gatcgtgcgc ccagaagact
    25081 caatggcggc gctggaagag atgactggtc atgcagaaaa agtcctgcag ttgctgggcc
    25141 tgccgtaccg taaaatcatc ctttgcactg gcgacatggg ctttggcgct tgcaaaactt
    25201 acgacctgga agtatggatc ccggcacaga acacctaccg tgagatctct tcctgctcca
    25261 acgtttggga tttccaggca cgtcgtatgc aggcacgttg ccgcagcaag tcggacaaga
    25321 aaacccgtct ggttcatacc ctgaacggtt ctggtctggc tgttggtcgt acgctggttg
    25381 cagtaatgga aaactatcag caggctgatg gtcgtattga agtaccagaa gttctgcgtc
    25441 cgtatatgaa cggactggaa tatattggct aatacccaat ttttctgaat ctaaaaagcg
    25501 cctgcgggcg ctttttttgt ctccctttga taccgaacaa taattactcc tcacttacac
    25561 gtaatactac tttcgagtga aaatctacct atctctttga ttttcaaatt attcgatgta
    25621 tacaagccta tatagcgaac tgctatagaa ataattacac aatacggttt gttactggaa
    25681 tcaatcgtga gcaagcttga gtgagccatt atgaaaacga aaatccctga tgcggtattg
    25741 gctgctgagg tgagtcgccg tggtttggta aaaacgacag cgatcggcgg cctggcaatg
    25801 gccagcagcg cattaacatt accttttagt cggattgcgc acgctgtcga tagcgccatt
    25861 ccaacaaaat cagacgaaaa ggttatctgg agcgcctgta cagttaactg tggtagtcgc
    25921 tgcccgctac gtatgcacgt cgtggacggt gaaatcaaat atgtcgaaac ggacaatacc
    25981 ggcgatgaca attacgacgg cctgcaccag gttcgcgcct gcctgcgtgg gcgttccatg
    26041 cgtcgccgtg tctacaatcc ggaccgcctg aaatatccga tgaaacgagt cggggcgcgc
    26101 ggtgaaggca aattcgagcg cattagctgg gaagaagcct acgacatcat cgcgaccaat
    26161 atgcagcgcc tgatcaaaga gtacggcaac gagtctatct atctgaacta tggcaccggt
    26221 acgctgggcg gcaccatgac ccgctcctgg ccgccgggaa ataccctggt cgcgcggctg
    26281 atgaactgct gcggcggcta tctgaaccat tacggcgact actcctccgc gcaaattgcg
    26341 gaaggtttga actataccta cggcggctgg gcagatggca acagcccgtc ggatatcgaa
    26401 aacagtaagc tggtagtgct gtttggtaat aaccctggcg aaacgcgaat gagtggcggt
    26461 ggggtgactt actatcttga acaggcacgc cagaaatcta atgcccgcat gatcatcatc
    26521 gatccgcgct ataccgacac cggtgccggg cgcgaagatg agtggatccc tattcgtccg
    26581 ggaacagatg ccgcactggt taacggtctg gcgtacgtca tgatcactga aaacctggtg
    26641 gatcaggcat tcctcgataa atattgcgtt ggctacgatg agaaaaccct gccagccagt
    26701 gcgccgaaaa atggccacta taaagcttat attctgggtg aagggccaga tggcgtggct
    26761 aaaacgccgg aatgggcctc gcaaatcact ggtgttccgg cagacaaaat catcaaattg
    26821 gctcgtgaaa tcggtagtac caaaccggcg tttatcagcc agggatgggg cccgcagcgt
    26881 cacgctaacg gtgaaatcgc aacccgtgct atctcgatgc tggcgattct gaccggtaac
    26941 gttggtatta acggaggcaa cagcggcgcg cgtgaaggtt catacagctt accgtttgtc
    27001 cgtatgccga ccttggaaaa cccgatccag accagcattt cgatgtttat gtggaccgat
    27061 gccattgaac gtggcccgga aatgacggcg ctgcgtgatg gtgtacgcgg gaaagataag
    27121 ctggatgtgc cgatcaaaat gatctggaac tatgccggta actgcctgat taaccagcat
    27181 tctgaaatca accgtaccca tgaaatcctt caggatgata agaagtgtga gctgattgtg
    27241 gttatcgact gccacatgac ctcatcggcg aaatatgctg acatcctgct gcctgactgc
    27301 accgcttccg aacagatgga ctttgcgctg gatgcatcct gcgggaatat gtcttacgtg
    27361 attttcaacg atcaggtgat taaaccgcgc tttgaatgta agaccatcta tgaaatgacc
    27421 agcgaactgg caaaacgtct tggcgttgag caacagttta ctgaaggccg tacccaggaa
    27481 gagtggatgc ggcatctgta tgcccagtcg cgggaagcga ttcctgaact gccaacgttt
    27541 gaagagttcc gcaagcaggg gatctttaaa aagcgcgacc cacaagggca tcacgttgct
    27601 tataaagcct tccgtgaaga tccgcaggca aacccactga ctacgccatc gggcaaaatt
    27661 gagatttatt cgcaggcgct ggctgacatt gccgctacct gggaattgcc tgaaggcgat
    27721 gtgatcgatc cactgccgat ctacacgccg ggctttgaaa gttatcagga tccgctgaac
    27781 aaacagtatc cgctgcagct tacaggtttc cactataaat ctcgcgttca ctcaacttac
    27841 ggcaacgttg atgtgctgaa agcggcttgc cgtcaggaaa tgtggatcaa cccgcttgat
    27901 gcccaaaaac gcggtatcca caacggcgat aaagtcagga tctttaacga tcgtggtgag
    27961 gttcatattg aggcgaaagt gacgccacga atgatgccgg gtgtggtcgc actgggtgaa
    28021 ggtgcctggt atgacccgga tgcaaaacgt gtcgataagg gtggttgtat taacgtactg
    28081 accactcaac gtccgtctcc tctcgctaag gggaatccgt cacatacaaa ccttgttcag
    28141 gttgaaaagg tgtaaggagt aaccgatgac aacccagtat ggatttttta ttgattccag
    28201 ccgttgcacc ggttgcaaaa cctgcgagct ggcctgtaaa gactacaaag atttgacgcc
    28261 agaagtcagc ttccgccgca tttatgaata tgctggcggc gactggcagg aagataacgg
    28321 tgtctggcac cagaacgtgt ttgcctacta tctgtcgatt tcatgtaacc actgcgaaga
    28381 tccggcttgt actaaagtct gcccgagcgg tgcgatgcat aaacgtgaag atggttttgt
    28441 tgtggtcgat gaagatgtgt gcattggctg ccgctactgc catatggctt gcccgtatgg
    28501 cgcaccgcaa tataacgaaa cgaaaggcca tatgaccaaa tgcgatggtt gttatgaccg
    28561 tgttgcggag ggtaaaaagc cgatctgtgt tgaatcttgt ccgctgcggg cgctggattt
    28621 cggccctatc gacgagctgc gtaaaaaaca tggcgatctg gcggccgttg cgccgttgcc
    28681 gcgagctcac tttaccaaac cgaatattgt gatcaaaccc aatgccaata gccgcccgac
    28741 cggggatacc actggctatc tggcaaaccc gaaggaggtg tgagatggga agtggatggc
    28801 atgaatggcc gctgatgatc ttcacggtct tcgggcaatg tgtagcaggt ggttttatcg
    28861 ttctggcttt ggcgctgctc aaaggcgacc tgcgagcaga agcccagcag cgtgttatcg
    28921 cctgcatgtt tggtttatgg gtgctgatgg gcattggctt tatcgcctct atgctccatc
    28981 ttggttcacc aatgcgcgct tttaactcgc tcaaccgggt aggggcttca gcactcagta
    29041 acgaaatcgc cagcggttcg atcttttttg ccgtaggcgg catcggctgg ttgctggcaa
    29101 tgctgaaaaa gctgtcaccg gcattgcgta cgctgtggct gatagtgacg atggttcttg
    29161 gcgtcatctt tgtctggatg atggtgcgtg tgtataacag cattgatacc gttccgacct
    29221 ggtacagcat ctggacgccg atgggcttct tcctgacgat gtttatgggc ggcccgttac
    29281 tgggttacct gttgttgagt ctggctggcg tcgatggctg ggcgatgcgt ctgctgccag
    29341 caatttctgt actggcactg gtagtgagtg gcgtggtgtc agtgatgcag ggcgcagagc
    29401 tggcgactat tcatagttct gtgcagcagg ccgcagcgct ggtgccggac tatggtgcgc
    29461 tgatgtcctg gcggatcgtg cttttggccg ttgccctgtg cttgtggatt gcaccacagc
    29521 taaaaggtta tcagcctgcg gttccgctac tttctgtatc attcattctg cttctggcag
    29581 gggaattaat cggtcgcggc gtattctatg gtttgcatat gaccgtgggg atggccgtcg
    29641 caagctaatc ataacaaccg gggtttcggc cccggttctc ttttatttct gcttcgttaa
    29701 cgtgtcataa ctggtcatca aattacgata atcaggaatg tggttagaga acaacgtcgc
    29761 cagtccttca atatcattac gccagtcgcg atgcagctcg cacgccacgc cgaaccatgt
    29821 catcaattgc gcaccagctt gcgacaagcg atcccatgcc gaatgccggg taatttcatt
    29881 aaaggtccct gacgcgtcag tcacgacaaa gacgtcaaac ccttcttcaa tggctgaaag
    29941 cgccgggaat gccacgcaaa cttcggttac cacaccggca ataattaact gttttttacc
    30001 tgtcgctttg acagctttta caaaatcttc gttatcccag gcgttaatat ttcccgggcg
    30061 agcaatgtaa ggtgtatcgg ggaattgtgc tttcagttct ggaactaatg ggccgttagg
    30121 accggtttca aaactggtgg taagaatagt tggtaagttg aaatacttag ccaggtcacc
    30181 cagcgccagc acgttatttt taaacttatc gggttcgata tcccgtacaa gggaaagtaa
    30241 accagcctgg tgatcaacaa gcaaaacggc agcatcattt ttatcaagac gaacatacgg
    30301 tttggtcatc ctcttctcct ttcgagagtc agtggtacgt ctgaaatcga tcagacgcga
    30361 tgcattgctc tgaaagcata gacgggaaat atgagtttgc tgtgaccatg aaatttttcg
    30421 actgaacgaa gcgtatgaaa tttgtgttag ttcaataaaa acaatcagat gagactaatc
    30481 atctcttcag cattagcgtt atgaatgagt aatataaatc gataataccg ccgctgggat
    30541 atcgcgtatt ttcacccatt gacaatgttt ttggcggtgg catgatgcgc atgaaatttg
    30601 aacttcctca cggttttaat tcatgtccac gtatacccag cctgtcatgc ttttgctgtc
    30661 tggcctgctt ttgttgactc tggcgattgc ggtgttaaat acactcgtgc cgctttggct
    30721 cgcccaggaa cacatgtcca catggcaggt aggcgttgtc agctcatcct attttaccgg
    30781 caaccttgtc ggtacattgc tgacagggta tgtcattaag cgcattggct ttaaccgcag
    30841 ctattatctg gcctccttca tttttgccgc tggctgtgcc ggccttggcc tgatgattgg
    30901 attctggagc tggttggctt ggcgttttgt cgcgggcgtc ggctgtgcca tgatttgggt
    30961 ggttgttgag agcgcgctga tgtgcagtgg gacgtcacgt aaccgtgggc gtttgcttgc
    31021 tgcgtatatg atggtttatt acgtgggaac gtttttaggc cagttactgg tcagcaaagt
    31081 ttcaaccgag ctgatgtccg tattgccgtg ggttacaggt ttgacgttgg cagggatctt
    31141 accgctgttg tttacgcgtg tgctgaatca gcaggctgaa aaccatgatt cgacgtcaat
    31201 tacgtcaatg ctaaaactcc gtcaggcgcg gcttggcgtg aatggctgca ttatctcagg
    31261 aatcgttctg ggatctctat atggcctgat gccgctgtac ctcaatcaca aaggggtgag
    31321 caatgccagc attggtttct ggatggcggt actggtcagt gcgggtatcc ttggacaatg
    31381 gccgattgga cgtctggcgg ataagtttgg tcgactgctg gtgttgcgtg ttcaggtctt
    31441 tgtcgtcatt ctcggcagta tcgcgatgct tagccaggcg gcgatggccc cagcgttatt
    31501 catcctcggt gccgctggct ttacgctata tccggtggcg atggcatggg cttgcgagaa
    31561 agttgaacat catcaactgg tggcgatgaa ccaggcctta ctgttgagct atactgtggg
    31621 aagtctgctt ggcccgtcat ttaccgctat gctaatgcag aatttctccg ataatttatt
    31681 gtttatcatg atcgccagcg tatcgtttat ctatttgctg atgctgctgc gcaacgccgg
    31741 tcatacgccg aaacccgttg ctcacgtgta aatgaattca agcagagtgt gaacttactg
    31801 tttcacactc tgcttttttg tttcttctat ctgacttgct ttattccaaa ttttattcgt
    31861 ttaaaaataa aatgtgcagc aggttataat tttgcatttc gctatttccg cacttcttat
    31921 ttgccgcgca taatccctcg ttttacagat gcccctttaa ttttggcgaa ggatttgtct
    31981 atggctggga atgttcagga aaaacagttg cgatggtaca acattgcgct gatgtctttt
    32041 atcactgtct ggggttttgg caacgttgtt aataactatg ccaaccaggg gctggtggtt
    32101 gttttttcat gggtgtttat ctttgcactc tatttcacac cttatgcgct aattgttggt
    32161 cagttaggct cgaccttcaa agatgggaag ggcggggtca gtacctggat taaacacacg
    32221 atgggacccg gactggctta tctcgccgcg tggacctact gggtggtgca tattccctat
    32281 ctggcacaaa aaccccaggc aattctgatt gcgctcggtt gggcgatgaa aggcgacggt
    32341 tcgctaatca aagaatattc agtcgtagcg ttacaggggt taacgctggt gctgtttatc
    32401 ttctttatgt gggttgcttc acgcggtatg aaatcgctga aaatcgtcgg ttctgtggca
    32461 gggattgcta tgtttgttat gtcgctcctg tatgtggcga tggcggtaac cgcgcctgca
    32521 attactgaag tgcatattgc gaccacaaac attacctggg aaacgttcat tcctcatatc
    32581 gactttacct acattaccac tatttcaatg ctggttttcg cggttggcgg agcagagaag
    32641 atttctcctt acgttaatca aacgcgcaac ccaggaaaag aatttccaaa agggatgtta
    32701 tgcctggcgg tgatggttgc ggtttgtgcc attctgggct cgctggcgat ggggatgatg
    32761 tttgattcgc gtaatatccc ggatgactta atgaccaacg gtcagtatta cgcctttcag
    32821 aagctgggcg agtattacaa catgggtaat actttaatgg tgatttacgc cattgcgaat
    32881 accctgggac aagtagcggc gctggtattc tcgattgatg ccccgcttaa agtgctatta
    32941 ggtgatgctg acagcaaata tattccagcc agtttatgtc gtaccaacgc ttctggtacg
    33001 cccgttaatg gctattttct gaccctggta ctggtggcga ttctgattat gctgccgact
    33061 ctcggcattg gtgatatgaa caatctctat aaatggctgt tgaaccttaa ttcggtagtg
    33121 atgccgctgc gttatttatg ggtatttgtt gcatttattg cagtcgttcg cttggcgcag
    33181 aaatataaac cagaatatgt ctttattcgt aataagcctc tggcaatgac cgtcgggatt
    33241 tggtgttttg cctttaccgc ctttgcctgt ttgacgggga tcttcccgaa aatggaagcc
    33301 ttcactgcag agtggacctt ccagttggcg ctgaatgttg caacgccgtt tgtgctggta
    33361 ggattaggac tgatattccc gctgctggcg cgtaaagcga atagtaaata attattgtgg
    33421 tcggtgacgc tgactctggc agatctgacc cgtttttaca taatcgagaa atgcgcgcaa
    33481 gccgcaggac atatactggc ggtttggata atagatctgg aagcctggac gctctgtgct
    33541 ccagtcttcc agtacacatt ctaaacgacc agtatcaagg tactccttga tctgttcata
    33601 gagcagatac ccgataccag cacccatcaa aacggcctcc agttcagcat caacatcatc
    33661 cagaatgata tttcctgcga cagcaatttc cagctccttt gcaaattgcc agtggaaagg
    33721 tttgccgctg ggataacgaa aaacaacaca ttgatgatta agcagatcat gaggatggcg
    33781 gggtttgcca tatcttgcaa agtactctgg cgttgctgct acacataatt tcactggcgg
    33841 gccgatcgcc acgctgatca tgtctttttc gacgatgcaa ctaagtcgaa cgccagcgtc
    33901 aaagccctgt tggacgatat cgacaagaga gtcgtcagtt gtgagctcga ctttaatatc
    33961 aggatattca cgtgtgaaac caaccagtaa agacattaaa aatatacgtg cagctacccg
    34021 ggcggcattg attttgagcg ttcctgtcgg tgtcagacga aaatcattca tctcatctaa
    34081 catgatctga atttcgtcga aagctgggcg caatcgttca tagagattag aacccgcttc
    34141 cgttaacgat acgcttcggg ttgtccgatt gaataagcga attttaagac gttgttccag
    34201 tgttttaata ctatggctaa tggcggacga ggataagcct aactcatcgc ccgctgcacg
    34261 aaagctttga ttacgggcca cggcaaagaa agtggcaaag tcagacatat tcatccgcat
    34321 tagtgaaaat ccttcattaa ctcatcctga atcatcacgt ttacaggatt atgccgcctg
    34381 cgtaaagtgc gctccagaac ttaacgtgga ggtaaaatta tgcagtctga acgtatttat
    34441 ttggtatggg cccatcctcg tcatgattca ttgaccgcac atattgctga tgcgatccat
    34501 cagcgggcaa tggagcggaa aatacaggtg acggaactcg atttatatcg gcgtaatttc
    34561 aacccagtga tgacgccgga agatgaacca gactggaaga atatggataa acgttattct
    34621 ccagaggttc atcagcttta ttcagagctg cttgaacatg acacgttagt ggtggttttt
    34681 cctctctggt ggtacagctt cccggcaatg ctaaaaggat atattgacag agtatggaat
    34741 aatgggctgg cttatggaga tgggcacaaa ttaccattca ataaagttcg ttgggtggcg
    34801 ctggttggag gagacaaaga atcatttgtc cagatgggct gggaaaaaaa tataagcgat
    34861 tatttaaaaa atatgtgcag ttatcttggt attgaagatg ccgatgtcac tttcttgtgt
    34921 aatacagtgg tattcgatgg ggaagaactt cacgcgagct attatcagtc gttattatct
    34981 caggtacggg atatggtaga tgcactataa gatgtgttaa aaacgctgta gcagaatgaa
    35041 gcgcggaata aaaaagcggc aactcaataa agttgccgct ttacggggaa attagaacat
    35101 taccttatga ccgtactgct caagaatgcc tttcacgcgt tccatggtct ctttcttcgg
    35161 tggtttaaca ccgtcgagtt tgtactcttc acccattgcc acccatttgt gtttgcccag
    35221 ctcgtggtag gggagaagct cgattttctc aacgttgccc atatcacggg taaattcacc
    35281 gaggcgatgc gctgaatcgt catcgtcaga ccagcctggg acaacaacgt agcggatcca
    35341 caccttcaca tttttgttcg ccagatattt agcgaactcc agcgtgcggt ggttggaaac
    35401 tccaaccaga ttttggtgga tctcgtcgtt catctgtttg agatcgagca ttaccaggtc
    35461 ggttacttcc agcagttcat caatcaccgg atcgtaacga cgaacaaaac cgttggtgtc
    35521 cagacaggta tgaatgcctt cttttttgca ggcgcggaac cagtcacgaa caaactcagc
    35581 ttgcaggatt gcttcaccgc cggatgcggt aacgccgccg ccggaagcgt tcataaagtg
    35641 gcgataggtc accacttcct tcatcaaatc ttcaacggta acttctttac cgccatgcgt
    35701 gtcccaggtg tcgcggttat gacaatacag gcagcgcatc aggcagccct ggaaaaaggt
    35761 gataaagcga atacctgggc cgtctacggt tccacaggat tcaaaggagt gaatgcgacc
    35821 aataactgac attgcggtgt ttctccagat gtggcccatc tgaggccgtg ttggtgcgca
    35881 gctcgaaggc tacgtcgagt ctgttttggc agtcacctta aagtatagat agctgacaaa
    35941 aaaggctctc gcgctaaaaa aggccccact ttcgtggagc ctttattgta cgctttttac
    36001 tgtacgattt cagtcaaatc taattacata gattgagtga aggtacgagt aataacgtcc
    36061 tgctgctgtt ctttagtcag cgagttgaaa cgtactgcgt agccagatac acggatggtc
    36121 agctgcggat atttttccgg gttttccatc gcgtcgagca gcatttcacg gttcatcacg
    36181 ttaacgttca ggtgctgacc accttcgatg gatgcttcgt ggtggaagta accatccatc
    36241 agaccagcca ggttggtctt acgaacttcg tcgtctttac ccagtgcgtt cggaacgata
    36301 gagaaggtgt aggagatacc atctttagcg taagcaaacg gcagtttagc aacggaagtc
    36361 agagaggcta ctgcaccttt ctggtcacga ccgtgcatcg ggttagcacc cggtccgaac
    36421 ggcgcgccag cacgacgacc gtctggggtg ttacccgttt tcttaccata cacaacgtta
    36481 gaagtgatgg tcagaacaga ctgagtcggg atagcgtcac ggtaggtgtg cagtttctga
    36541 attttcttca tgaaacgttc taccaggtca acagccaggt catctacacg cggatcattg
    36601 ttaccaaact gcgggtattc gccttcgatt tcgaagtcga tagccagacc gtcttcgtca
    36661 cgaatcggtt taactttcgc atatttgatt gcagacaggg agtcagcagc aacggacaga
    36721 ccagcgatac cacacgccat ggtgcggata acgtcacggt cgtgcagcgc catcagagag
    36781 gcttcgtagc tgtacttgtc gtgcatgtag tggatgatgt tcagtgcagt gatgtactgt
    36841 ttagccagcc agtccatgaa gtgatccatg cgctccatca cttcatcata gttcaggaca
    36901 tcgcctttga tcggttcaga cttcggacca acctgcattt tcagtttttc gtcaacgccg
    36961 ccgttgattg cgtacagcat ggttttcgcc aggtttgcac gcgcaccgaa gaactgcatt
    37021 tgtttaccaa cgatcatcgg gcttacgcag caagcaatag cgtagtcatc gttgttgaag
    37081 tccggacgca tcaggtcatc gttctcatac tgcagagaag aggtgtcgat ggacacttta
    37141 gcggcgaatt tcttgaagtt cagcggcagt ttttcagacc acagaatggt catgttcggt
    37201 tccggagacg gacccatggt gtacagggtg ttcaggaaac ggaagctgtt tttggtaacc
    37261 agggtacgac cgtcgaggcc cataccaccg atagattcgg ttgcccagat cgggtcgcca
    37321 gagaacagtt catcgtattc cggagtacgc aggaagcgaa ccatacgcag tttcatgacc
    37381 aggtggtcaa ccatttcctg cgcttcttgt tcggtgatct tgccagcttt caggtcacgt
    37441 tcgatgtaca catccaggaa ggtggaggta cgaccgaagg acattgcagc accgttctga
    37501 gacttaacag cagccaggta gccgaagtaa gtccactgga tagcttcctg agcgttggta
    37561 gccggaccag agatgtcgta gccgtatttc gcagccattt ctttcatctg actcagagcg
    37621 cggtgctgtt cagcgatttc ttcgcgcaga cggatagtct gttccaggtt tacgccgttt
    37681 tccagatcag cctgcagaga agtgaactgt gccagtttgt ctttcatcag gtagtcgata
    37741 ccgtacagcg caacgcgacg gtagtcaccg atgatacggc cacggccata tgcatctggc
    37801 agaccggtca gaacaccaga tttacggcaa cgcaggatgt ccggagtgta aacgtcgaac
    37861 acgccctggt tgtgagtttt acggtattca gtgaagattt ttttgatcat cggatccagt
    37921 tcgcggttgt acgctttgca ggaaccttcg atcattttga taccaccgaa cgggataaga
    37981 gcacgtttca gcggagcttc agtctgcaga ccaacgattt tctcaagctg cttgttgatg
    38041 tagccagcgt cgtgagaggt gatggtggaa gcaacagcgg tgtcaaagtc aactggcgcg
    38101 tgagtgcggt tttccagttt aacgccttcc attactttgt cccacagggt ggtggtcgct
    38161 tcagtagcgc cagccaggaa ggactcgtca ccctcgtacg gagtgtagtt tttctgaatg
    38221 aagtcacgga cgtttacttc attctgccag tcacctttgg taaaaccttc ccaggctgtg
    38281 gctaactttt cattaagctc ggacatgtaa cacctacctt cttaagtgga ttttttattt
    38341 actgcgtact tcgacaacca ttaatggtgg tcgttttcac gcaggtaaat gacccagtat
    38401 gtcaacccaa ccaacaaacc accaccgata atgttgccga tcgtaaccgg aatcaggtta
    38461 tcagtgatga aattcatcac ggtcaggtga gaaaaatttt ccggtgcaga accgactgcg
    38521 gtccaaaatt ccggggatgc gaagtcgcgg attacaatac ccatcgggat cataaacatg
    38581 tttgcgatac tgtgctcaaa accgctggca acaaacatcg cgaccggcag caccataatg
    38641 aacgctttgt ccatcaggct gcggccagaa taactcatcc atactgccag acataccatc
    38701 aggtttgcca ggataccaag acagacggcc tcaataaaag tatggtgcac tttgtggtcg
    38761 gcggtttgta ggacgtttag tccccattga ccatttgcgg tcatatactc gccggaaagc
    38821 cacattaaaa gtacaaacag cagtgcgccg accaggttgc caaaatagac atttagccag
    38881 tttttcgcca actgacccca ggtgatgcgc ccactcgcct tagcaacaac aatcaacacg
    38941 gtggaagtaa agagatcggc tccgcagaca acacaaagaa tcagccccag agagaagcaa
    39001 atgccgccaa ccagttttgc catgccgaag ggcattgtgc ctgtgccagt ggttgctgtg
    39061 atatagaaga cgaatgcgat tgagatgaaa acaccggcgg taatcgccag atagaaagtc
    39121 ttaagcggat gtttcgttgc tttatagaca cccgcctctt cggccacttt ggccattgca
    39181 gcaggaagta aaagatcaaa agggttgtca gctttcacac taactctctc tttattaagt
    39241 cggcgacgag atactaacaa agcattatag atgagaaatt gatatagatc atatctcgcc
    39301 tggcttatag gcccgtaact cgcatggttt t
//
LOCUS       DAPOAV010000038        38248 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.038, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000038 DAPOAV010000000
VERSION     DAPOAV010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 38248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38248
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.038"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(29..346)
                     /gene="metJ"
                     /locus_tag="RN951_002232"
     CDS             complement(29..346)
                     /gene="metJ"
                     /locus_tag="RN951_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015855437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="met regulon transcriptional regulator MetJ"
                     /protein_id="HDX2527223.1"
                     /translation="MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRR
                     QVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPET
                     WEY"
     gene            623..1783
                     /gene="metB"
                     /locus_tag="RN951_002233"
     CDS             623..1783
                     /gene="metB"
                     /locus_tag="RN951_002233"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HDX2527224.1"
                     /translation="MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAH
                     DYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYG
                     GSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKIC
                     HLAREVGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDV
                     VTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLY
                     HPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGLSLFTLAESLGGVESLI
                     SHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG"
     gene            1786..4218
                     /gene="metL"
                     /locus_tag="RN951_002234"
     CDS             1786..4218
                     /gene="metL"
                     /locus_tag="RN951_002234"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase II"
                     /protein_id="HDX2527225.1"
                     /translation="MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEYSQPDDM
                     MVVSAAGSTTNQLINWLKLSQTDRLSAHQVQQTLRRYQCDLISGLLPAEEADSLISAF
                     VSDLERLAALLDSGINDAVYAEVVGHGEVWSARLMSAVLNQQGLPAAWLDAREFLRAE
                     RAAQPQVDEGLSYPLLQQLLVQHPGKRLVVTGFISRNNAGETVLLGRNGSDYSATQIG
                     ALAGVSRVTIWSDVAGVYSADPRKVKDACLLPLLRLDEASELARLAAPVLHARTLQPV
                     SGSEIDLQLRCSYTPDQGSTRIERVLASGTGARIVTSHDDVCLIEFQVPASQDFKLAH
                     KEIDQILKRAQVRPLAVGVHNDRQLLQFCYTSEVADSALKILDEAGLPGELRLRQGLA
                     LVAMVGAGVTRNPLHCHRFWQQLKGQPVEFTWQSDDGISLVAVLRTGPTESLIQGLHQ
                     SVFRAEKRIGLVLFGKGNIGSRWLELFAREQSTLSARTGFEFVLAGVVDSRRSLLSYD
                     GLDASRALAFFNDEAVEQDEESLFLWMRAHPYDDLVVLDVTASQQLADQYLDFASHGF
                     HVISANKLAGASDSNKYRQIHDAFEKTGRHWLYNATVGAGLPINHTVRDLIDSGDTIL
                     SISGIFSGTLSWLFLQFDGSVPFTELVDQAWQQGLTEPDPRDDLSGKDVMRKLVILAR
                     EAGYNIEPDQVRVESLVPAHCEGGSIDHFFENGDELNEQMVQRLEAAREMGLVLRYVA
                     RFDANGKARVGVEAVREDHPLASLLPCDNVFAIESRWYRDNPLVIRGPGAGRDVTAGA
                     IQSDINRLAQLL"
     gene            4567..5457
                     /gene="metF"
                     /locus_tag="RN951_002235"
     CDS             4567..5457
                     /gene="metF"
                     /locus_tag="RN951_002235"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HDX2527226.1"
                     /translation="MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNS
                     IDRLSSLKPKFVSVTYGANSGERDRTHSIIKGIKERTGLEAAPHLTCIDATPDELRTI
                     ARDYWNNGIRHIVALRGDLPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAK
                     SAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFK
                     QAKKFADMTNVRIPAWMAQMFDGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYT
                     LNRAEMSYAICHTLGVRPGL"
     gene            5786..7966
                     /gene="katG"
                     /locus_tag="RN951_002236"
     CDS             5786..7966
                     /gene="katG"
                     /locus_tag="RN951_002236"
                     /EC_number="1.11.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase/peroxidase HPI"
                     /protein_id="HDX2527227.1"
                     /translation="MSTSDDIHNTTATGKCPFHQGGHDQSAGAGTTTRDWWPNQLRVD
                     LLNQHSNRSNPLGEDFDYRKEFSKLDYYGLKKDLKALLTESQPWWPADWGSYAGLFIR
                     MAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWA
                     DLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLG
                     ATEMGLIYVNPEGPDHSGEPLSAAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAG
                     PTSNVGPDPEAAPIEEQGLGWASTYGSGVGADAITSGLEVVWTQTPTQWSNYFFENLF
                     KYEWVQTRSPAGAIQFEAVDAPEIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRR
                     FLNDPQAFNEAFARAWFKLTHRDMGPKSRYIGPEVPKEDLIWQDPLPQPIYNPTEQDI
                     IDLKFAIADSGLSVSELVSVAWASASTFRGGDKRGGANGARLALMPQRDWDVNAAAVR
                     ALPVLEKIQKESGKASLADIIVLAGVVGVEKAASAAGLSIHVPFAPGRVDARQDQTDI
                     EMFELLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTALVGGMRVLGANFD
                     GSKNGVFTDRVGVLSNDFFVNLLDMRYEWKATDESKELFEGRDRETGEVKFTASRADL
                     VFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNLDRFDLL"
     gene            8059..8964
                     /gene="yijE"
                     /locus_tag="RN951_002237"
     CDS             8059..8964
                     /gene="yijE"
                     /locus_tag="RN951_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418378.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine transporter YijE"
                     /protein_id="HDX2527228.1"
                     /translation="MSAAGKSNPLAISGLVVLTLIWSYSWIFMKQVTSYIGAFDFTAL
                     RCIFGALVLFIVLLLRGRGMRPTPFKYTLAIALLQTCGMVGLAQWALVSGGAGKVAIL
                     SYTMPFWVVIFAALFLGERLRRGQYFAILIAAFGLFLVLQPWQLDFSSMKSAMLAILS
                     GVSWGASAIVAKRLYARHPRVDLLSLTSWQMLYAALVMSVVALLVPQREIDWQPTVFW
                     ALAYSAILATALAWSLWLFVLKNLPASIASLSTLAVPVCGVLFSWWLLGENPGAVEGS
                     GIVLIVLALALVSRKKKEAVSVKRI"
     gene            complement(8991..9608)
                     /locus_tag="RN951_002238"
     CDS             complement(8991..9608)
                     /locus_tag="RN951_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1287 domain-containing protein"
                     /protein_id="HDX2527229.1"
                     /translation="MKASLALLSLLTAFTSHSLKSPAVPPTVVQIQANTNLAIADGAR
                     QQIGSTLFYDPAYVQLTYPGGDVPQERGVCSDVVIRALRSQKVDLQKLVHEDMAKNFA
                     EYPQKWKLKRSDSNIDHRRVPNLETWFSRHDKTRPTSKNPSDYQAGDIVSWRLDNGLA
                     HIGVVSDGFARDGTPLVIHNIGAGAQEEDVLFNWRMVGHYRYFVK"
     gene            complement(9883..10986)
                     /gene="gldA"
                     /locus_tag="RN951_002239"
     CDS             complement(9883..10986)
                     /gene="gldA"
                     /locus_tag="RN951_002239"
                     /EC_number="1.1.1.6"
                     /EC_number="1.1.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418380.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional L-1,2-propanediol
                     dehydrogenase/glycerol dehydrogenase"
                     /protein_id="HDX2527230.1"
                     /translation="MDRIIQSPGKYIQGADVINRLGEYLKPLAERWLVVGDKFVLGFA
                     QSTVEKSFKDAGLVVEIAPFGGECSQNEIDRLRGIAETAQCGAILGIGGGKTLDTAKA
                     LAHFMGVPVAIAPTIASTDAPCSALSVIYTDEGEFDRYLLLPNNPNMVIVDTKIVAGA
                     PARLLAAGIGDALATWFEARACSRSGATTMAGGKCTQAALALAELCYNTLLEEGEKAM
                     LAAEQHVVTPALERVIEANTYLSGVGFESGGLAAAHAVHNGLTAIPDAHHYYHGEKVA
                     FGTLTQLVLENAPVEEIETVAALSHAVGLPITLAQLDIKEDVPAKMRIVAEAACAEGE
                     TIHNMPGGATPDQVYAALLVADQYGQRFLQEWE"
     gene            complement(10997..11659)
                     /gene="fsa"
                     /locus_tag="RN951_002240"
     CDS             complement(10997..11659)
                     /gene="fsa"
                     /locus_tag="RN951_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDX2527231.1"
                     /translation="MELYLDTANVAEVERLARIFPIAGVTTNPSIIAASKESIWEVLP
                     RLQKAIGDEGILFAQTMSRDAQGMVEEAKRLRDAIPGIVVKIPVTSEGLAAIKILKKE
                     GITTLGTAVYSAAQGLLAALAGAKYVAPYVNRVDAQGGDGIRTVQELQTLLEMHAPES
                     MVLAASFKTPRQALDCLLAGCESITLPLDVAQQMLNTPAVESAIEKFEHDWNAAFGTT
                     HL"
     gene            complement(11671..14172)
                     /gene="ptsP"
                     /locus_tag="RN951_002241"
     CDS             complement(11671..14172)
                     /gene="ptsP"
                     /locus_tag="RN951_002241"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDX2527232.1"
                     /translation="MALIVEFICELPNGVHARPASHVETLCNTFSSQIEWHNLRTDRK
                     GNAKSALALIGTDTLAGDNCQLLISGADEQEAHQRLSQWLRDEFPHCDAPLAEVKSDE
                     LEPLPVSLTNLNPQIIRARTVCSGSAGGILTPISSLDLNALGNLPAAKGVDAEQSALE
                     NGLTLVLKNIEFRLLDSDGATSAILEAHRSLAGDTSLREHLLAGVSAGLSCAEAIVAS
                     ANHFCEEFSRSSSSYLQERALDVRDVCFQLLQQIYGEQRFPAPGKLTQPAICMADELT
                     PSQFLELDKNHLKGLLLKSGGTTSHTVILARSFNIPTLVGVDIDALTPWQQQTIYIDG
                     NAGAIVVEPGEAVARYYQQEARVQDALREQQRVWLTQQARTADGIRIEIAANIAHSVE
                     AQAAFGNGAEGVGLFRTEMLYMDRTSAPGESELYNIFCQALESANGRSIIVRTMDIGG
                     DKPVDYLNIPAEANPFLGYRAVRIYEEYASLFTTQLRSILRASAHGSLKIMIPMISSM
                     EEILWVKEKLAEAKQQLRNEHIPFDEKIQLGIMLEVPSVMFIIGQCCEEIDFFSIGSN
                     DLTQYLLAVDRDNAKVTRHYNSLNPAFLRALDYAVQAVHRQGKWIGLCGELGAKGSVL
                     PLLVGLGLDELSMSAPSIPAAKARMAQLDSRECRKLLNQAMACRTSLEVEHLLAQFRM
                     TQQDAPLVTAECITLESDWRSKEEVLKGMTDNLLLAGRCRYPRKLEADLWAREAVFST
                     GLGFSFAIPHSKSEHIEQSTISVARLQAPVRWGDDEAQFIIMLTLNKHAAGDQHMRIF
                     SRLARRIMHEEFRNALVNAASADAIASLLQHELEL"
     gene            14481..15560
                     /locus_tag="RN951_002242"
     CDS             14481..15560
                     /locus_tag="RN951_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HDX2527233.1"
                     /translation="MNELVQILKNTRQHLMTGVSHMIPFVVSGGILLAVSVMLYGKGA
                     VPDAVADPNLKKLFDIGVAGLTLMVPFLAAYIGYSIAERSALAPCAIGAWVGNSFGAG
                     FFGALIAGIIGGIVVHYLKKIPVHKVLRSVMPIFIIPIVGTLITAGIMMWGLGEPVGA
                     LTNSLTQWLQGMQQGSIVMLAVIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTVVAI
                     AAVGICIPPLGMGLATLIGRKNFSAEERETGKAALVMGCVGVTEGAIPFAAADPLRVI
                     PSIMVGSVCGAVTAALVGAQCYAGWGGLIVLPVVEGKLGYIAAVAVGAVVTAVCVNVL
                     KSLARKNGSSTDEKEDDLDLDFEIN"
     gene            15575..15895
                     /locus_tag="RN951_002243"
     CDS             15575..15895
                     /locus_tag="RN951_002243"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HDX2527234.1"
                     /translation="MTKIIAVTACPSGVAHTYMAAEALESAAKAKGWEVKVETQGSIG
                     LENELTAEDVASADMVILTKDIGIKFEERFAGKTIVRVNISDAVKRADAIMSKIEAHL
                     AQTA"
     gene            15946..18243
                     /locus_tag="RN951_002244"
     CDS             15946..18243
                     /locus_tag="RN951_002244"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDX2527235.1"
                     /translation="MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRA
                     KATAYILEHVEISIRDEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFA
                     ISEEDKRIYREELFPYWEKRSMKDFINGQMTDEVKAATNTQIFSINQTDKGQGHIIID
                     YPRLLNHGLGELVAQMQQHCQQQPENHFYQAALLLLEASQKHILRYAELAETMAANCT
                     DAQRREELLTIAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYM
                     LPFYQTSLTQGEDAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLT
                     ENGRSAVNVLSFLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRFGTGIPQIF
                     NDEVVVPAFLNRGVSLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHEN
                     EGNAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR
                     DITDGGARYNFSGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGE
                     KVRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVP
                     LGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVK
                     FTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA
                     GYSAFFVELSKEIQDDIIRRTAHQL"
     gene            18209..19087
                     /locus_tag="RN951_002245"
     CDS             18209..19087
                     /locus_tag="RN951_002245"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418387.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[formate-C-acetyltransferase]-activating enzyme"
                     /protein_id="HDX2527236.1"
                     /translation="MTSSAGQRISCNVVETRRDDVARIFNIQRYSLNDGEGIRTVVFF
                     KGCPHLCPWCANPESISGKIQTVRREAKCLHCAKCLRDADECPSGAFERIGRDISLDA
                     LEREVMKDDIFFRTSGGGVTLSGGEVLMQAEFATRFLQRLRLWGVSCAIETAGDAPAS
                     KLLPLAKLCDEVLFDLKIMDATQARDVVKMNLPRVLENLRLLVSEGVNVIPRLPLIPG
                     FTLSRENMQQALDVLIPLNIRQIHLLPFHQYGEPKYRLLGKTWSMKEVPAPSSADVAT
                     MREMAERAGLQVTVGG"
     gene            19089..19430
                     /locus_tag="RN951_002246"
     CDS             19089..19430
                     /locus_tag="RN951_002246"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HDX2527237.1"
                     /translation="MAYLVAVTACVSGVAHTYMAAERLEKLCLLEKWGVSIETQGALG
                     TENRLADEDIRRADVALLITDIELAGAEQFEHCRYVQCSIYAFLREPQRVMSAVRKVL
                     SAPQQTHLILE"
     gene            complement(19417..20268)
                     /locus_tag="RN951_002247"
     CDS             complement(19417..20268)
                     /locus_tag="RN951_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX2527238.1"
                     /translation="MYHDVSYLLSRLINGPLSLRQIYFASSNGSVPDLAYQVDFPRLE
                     IVLEGEFVDTGAGATLVPGDVLYVPAGGWNFPQWQAPATTFSVLFGKQQLGFSVVQWD
                     GKQYQNLAKQHVARRGPRIGSFLLQTLNEMQMQPQEQQTARLIVASLLSHCRDLLGSQ
                     IQTASRSQALFEAIRDYIDERYASALTRESVAQAFYISPNYLSHLFQKTGAIGFNEYL
                     NHTRLEHAKTLLKGYDLKVKEVAHACGFVDSNYFCRLFRKNTERSPSEYRRQYHSQLT
                     EKPTTPE"
     gene            complement(20483..22216)
                     /locus_tag="RN951_002248"
     CDS             complement(20483..22216)
                     /locus_tag="RN951_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase CptA"
                     /protein_id="HDX2527239.1"
                     /translation="MHSTEVQAKPLFSWKALGWALLYFWFFSTLLQAIIYISGYSGTN
                     GIRDSLLFSSLWLIPVFLFPKRIKIIAAVIGVVLWAASLAALCYYVIYGQEFSQSVLF
                     VMFETNTNEASEYLSQYFSLKIVLIALAYTAVAVLLWTRLRPVYIPKPWRYVVSFALL
                     YGLILHPIAMNTFIKNKPFEKTLDNLASRMEPAAPWQFLTGYYQYRQQLNSLTKLLNE
                     NNALPPLANFKDESGNEPRTLVLVIGESTQRGRMSLYGYPRETTPELDALHKTDPNLT
                     VFNNVVTSRPYTIEILQQALTFANEKNPDLYLTQPSLMNMMKQAGYKTFWITNQQTMT
                     ARNTMLTVFSRQTDKQYYMNQQRTQSAREYDTNVLKPFQEVLNDPAPKKLIIVHLLGT
                     HIKYKYRYPENQGKFDGNTDHVPPGLNAEELESYNDYDNANLYNDHVVASLIKDFKAA
                     NPNGFLVYFSDHGEEVYDTPPHKTQGRNEDNPTRHMYTIPFLLWTSEKWQATHPRDFS
                     QDVDRKYSLAELIHTWSDLAGLSYDGYDPTRSVVNPQFKETTRWIGNPYKKNALIDYD
                     TLPYGDQVGNQ"
     gene            complement(22398..25049)
                     /gene="ppc"
                     /locus_tag="RN951_002249"
     CDS             complement(22398..25049)
                     /gene="ppc"
                     /locus_tag="RN951_002249"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004203687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HDX2527240.1"
                     /translation="MNEQYSALRSNVSMLGKVLGETIKDALGEHILERVETIRKLSKS
                     SRAGNDANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPE
                     VIARTLRKLKNQPELSEDTIKKAVESLSLELVLTAHPTEITRRTLIHKMVEVNACLKQ
                     LDNKDIADYEHNQLMRRLRQLIAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWQGVP
                     NYLRELNEQLEENLGYKLPVEFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKAT
                     DLFLKDIQVLVSELSMVEATPELLALVGEEGAAEPYRYLMKNLRSRLMATQAWLEARL
                     KGEELPKPEGLLTQNEELWEPLYACYQSLQACGMGIIANGDLLDTLRRVKCFGVPLVR
                     IDIRQESTRHTEALGELTRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWQPSAE
                     TREVLDTCQVIAEAPQGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETL
                     DDLNNANDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIK
                     TCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLP
                     EITVSSLSLYTGAILEANLLPPPEPKESWRRIMDELSVISCDVYRGYVRENKDFVPYF
                     RSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQK
                     VVEDGKQSELEAMCRDWPFFSTRLGMLEMVFAKADLWLAEYYDQRLVDKALWPLGKEL
                     RNLQEEDIKVVLAIANDSHLMADLPWIAESIQLRNIYTDPLNVLQAELLHRSRQAEKE
                     GQEPDPRVEQALMVTIAGIAAGMRNTG"
     gene            complement(25647..26798)
                     /gene="argE"
                     /locus_tag="RN951_002250"
     CDS             complement(25647..26798)
                     /gene="argE"
                     /locus_tag="RN951_002250"
                     /EC_number="3.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylornithine deacetylase"
                     /protein_id="HDX2527241.1"
                     /translation="MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFK
                     DLGFNVEVQPVPGTRNKFNMLASIGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHD
                     GKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFAETTAL
                     RPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQ
                     LRDNLKERYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNELNG
                     LLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKLLGAKTEVVNYCTEA
                     PFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH"
     gene            26952..27956
                     /gene="argC"
                     /locus_tag="RN951_002251"
     CDS             26952..27956
                     /gene="argC"
                     /locus_tag="RN951_002251"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HDX2527242.1"
                     /translation="MLNTLIVGASGYAGAELVTYVNRHPHMNITALTVSAQSNDAGKL
                     ISDLHPQLKGIVDLPLQPMSDISEFSPGVDVVFLATAHEVSHDLAPQFLEAGCVVFDL
                     SGAFRVNDATFYEKYYGFTHQYPELLEQAAYGLAEWCGNKLKEANLIAVPGCYPTAAQ
                     LALKPLIDADLLDLNQWPVINATSGVSGAGRKAAISNSFCEVSLQPYGVFTHRHQPEI
                     ATHLGADVIFTPHLGNFPRGILETITCRLKSGVTQAQVAQVLQQAYAHKPLVRLYDKG
                     VPALKNVVGLPFCDIGFAVQGEHLIIVATEDNLLKGAAAQAVQCANIRFGYAETQSLI
                     "
     gene            27964..28740
                     /gene="argB"
                     /locus_tag="RN951_002252"
     CDS             27964..28740
                     /gene="argB"
                     /locus_tag="RN951_002252"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418394.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HDX2527243.1"
                     /translation="MMNPLIIKLGGVLLDSEEALERLFSALVNYRESHQRPLVIVHGG
                     GCVVDELMKGLNLPVKKKNGLRVTPADQIDIITGALAGTANKTLLAWAKKHQIAAVGL
                     FLGDGDSVKVTQLDEELGHVGLAQLGSPKLINSLLENGYLPVVSSIGVTDEGQLMNVN
                     ADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAAKAEQLIEQGIITDGMIVKV
                     NAALDAARTLGRPVDIASWRHAEQLPALFNGMPMGTRILA"
     gene            28801..30174
                     /gene="argH"
                     /locus_tag="RN951_002253"
     CDS             28801..30174
                     /gene="argH"
                     /locus_tag="RN951_002253"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HDX2527244.1"
                     /translation="MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKAL
                     VTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESDAEDIHSWVEGKLIDKVGQLGKK
                     LHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRA
                     QPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGF
                     ASATRNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSG
                     SSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDT
                     WLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAV
                     VEAIRQGKPLEDLPLSELQKFSQVIDEDVYPILSLQSCLDKRAAKGGVSPQQVAQAIA
                     FAQARLG"
     gene            30441..31358
                     /gene="oxyR"
                     /locus_tag="RN951_002254"
     CDS             30441..31358
                     /gene="oxyR"
                     /locus_tag="RN951_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator OxyR"
                     /protein_id="HDX2527245.1"
                     /translation="MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQIRKLEDELG
                     VMLLERTSRKVLFTQAGMLLVDQARTVLREVKVLKEMASQQGETMSGPLHIGLIPTVG
                     PYLLPHIIPMLHQTFPKLEMYLHEAQTHQLLAQLDSGKLDCVILALVKESEAFIEVPL
                     FDEPMLLAIYEDHPWANRECVPMADLAGEKLLMLEDGHCLRDQAMGFCFEAGADEDTH
                     FRATSLETLRNMVAAGSGITLLPALAVPPERKRDGVVYLPCIKPEPRRTIGLVYRPGS
                     PLRSRYEQLAEAIRARMDGHFDKVLKQAV"
     gene            complement(31341..32741)
                     /gene="sthA"
                     /locus_tag="RN951_002255"
     CDS             complement(31341..32741)
                     /gene="sthA"
                     /locus_tag="RN951_002255"
                     /EC_number="1.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418397.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Si-specific NAD(P)(+) transhydrogenase"
                     /protein_id="HDX2527246.1"
                     /translation="MPHSYDYDAIVIGSGPGGEGAAMGLVKQGARVAVIERYQNVGGG
                     CTHWGTIPSKALRHAVSRIIEFNQNPLYSDHSRLLRSSFADILNHADNVINQQTRMRQ
                     GFYERNHCEILQGNARFVDEHTLALDCPDGSVETLTAEKFVIACGSRPYHPTDVDFTH
                     PRIYDSDSILSMHHEPRHVLIYGAGVIGCEYASIFRGMDVKVDLINTRDRLLAFLDQE
                     MSDSLSYHFWNSGVVIRHNEEYEKIEGCDDGVIMHLKSGKKLKADCLLYANGRTGNTD
                     SLALQNIGLETDSRGQLKVNSMYQTAQPHVYAVGDVIGYPSLASAAYDQGRIAAQALV
                     KGEATAHLIEDIPTGIYTIPEISSVGKTEQQLTAMKVPYEVGRAQFKHLARAQIVGMN
                     VGTLKILFHRETKEILGIHCFGERAAEIIHIGQAIMEQKGGGNTIEYFVNTTFNYPTM
                     AEAYRVAALNGLNRLF"
     gene            33072..33722
                     /gene="fabR"
                     /locus_tag="RN951_002256"
     CDS             33072..33722
                     /gene="fabR"
                     /locus_tag="RN951_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor FabR"
                     /protein_id="HDX2527247.1"
                     /translation="MMGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGI
                     APTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGN
                     NPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVT
                     IVFSAGAEALDVGVEQRRQLEERLVLQLRMISKGAYYWYRREQEKTAIIPGNVKDE"
     gene            33722..34081
                     /locus_tag="RN951_002257"
     CDS             33722..34081
                     /locus_tag="RN951_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YijD family membrane protein"
                     /protein_id="HDX2527248.1"
                     /translation="MKQANQDRGTLLLALVAGLSINGTFAALFSSIVPFSVFPIISLV
                     LTVYCLHQRYLNRTMPVGLPGLAAACFILGVLLYSTVVRAEYPDIGSNFFPAVLSVIM
                     VFWIGAKMRNRKQEVAE"
     gene            complement(34121..35221)
                     /gene="trmA"
                     /locus_tag="RN951_002258"
     CDS             complement(34121..35221)
                     /gene="trmA"
                     /locus_tag="RN951_002258"
                     /EC_number="2.1.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (uridine(54)-C5)-methyltransferase TrmA"
                     /protein_id="HDX2527249.1"
                     /translation="MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHY
                     RMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPVLR
                     HKLFQIDYLTTLSNQAVVSLLYHKKLDDEWRQEAEALRDALRAQNLNVHLIGRATKTK
                     IELDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELY
                     CGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNG
                     VREFNRLQGIDLKSYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLE
                     TLSQTHKVERLALFDQFPYTHHMECGVLLTAK"
     regulatory      35335..35525
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            35590..37434
                     /gene="btuB"
                     /locus_tag="RN951_002259"
     CDS             35590..37434
                     /gene="btuB"
                     /locus_tag="RN951_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent vitamin B12 receptor BtuB"
                     /protein_id="HDX2527250.1"
                     /translation="MIKKASLLTACSVTAFSAWAQDTSPDTLVVTANRFEQPRSTVLA
                     PTTVVTRQDIDRWQSTSVNDVLRRLPGVDITQNGGSGQLSSIFIRGTNASHVLVLIDG
                     VRLNLAGVSGSADLSQFPIALVQRVEYIRGPRSAVYGSDAIGGVVNIITTRDEPGTEI
                     SAGWGSNSYQNYDVSTQQQLGDKTRVTLLGDYAHTHGYDVVAYGNTGTQAQTDNDGFL
                     SKTLYGALEHNFTDAWSGFVRGYGYDNRTNYDAYYSPGSPLLDTRKLYSQSWDAGLRY
                     NGELIKSQLITSYSHSKDYNYDPHYGRYDSSATLDEMKQYTVQWANNVIVGHGSIGAG
                     VDWQKQTTTPGTGYVEDGYDQRNTGIYLTGLQQVGDFTFEGAARSDDNSQFGRHGTWQ
                     TSAGWEFIEGYRFIASYGTSYKAPNLGQLYGFYGNPNLDPEKSKQWEGAFEGLTAGVN
                     WRISGYRNDVSDLIDYDDHTLKYYNEGKARIKGVEATANFDTGPLTHTVSYDYVDARN
                     AITDTPLLRRAKQQVKYQLDWQLYDFDWGITYQYLGTRYDKDYSSYPYQTVKMGGVSL
                     WDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF"
     gene            37379..38236
                     /gene="murI"
                     /locus_tag="RN951_002260"
     CDS             37379..38236
                     /gene="murI"
                     /locus_tag="RN951_002260"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418402.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HDX2527251.1"
                     /translation="MATKLQDGNTPCLAATPSEPRPTVLVFDSGVGGLSVYDEIRHLL
                     PDLHYIYAFDNVAFPYGEKSEAFIVERVVAIVTAVQERYPLALAVVACNTASTVSLPA
                     LREKFDFPVVGVVPAIKPAARLTANGIVGLLATRGTVKRSYTHELIARFANECQIEML
                     GSAEMVELAEAKLHGEDVSLDALKRILRPWLRMKEPPDTVVLGCTHFPLLQEELLQVL
                     PEGTRLVDSGAAIARRTAWLLEHEAPDAKSADANIAFCMAMTPGAEQLLPVLQRYGFE
                     TLEKLAVLG"
BASE COUNT         8666 a         9647 c        10619 g         9316 t
ORIGIN      
        1 attccactcc gcgccgctct tttttgcttt agtattccca cgtctccggg ttaatcccca
       61 tctcacgcat gatctctttt gccgcttccg ggatttcgtc gctgcgctct ttacgcagat
      121 cggcatcatc cggcaaaggt tgcccggtaa aggcatgcag aaacgcttcg cacagcagct
      181 cgctgttggt agcgtgacgc aggttgttca cctgacgacg cgtgcgttca tcggtgagga
      241 tttttaacac cttaagagga atggaaaccg taatcttttt gacttgttca ctcttcttgc
      301 cgtgctcagc gtatgggctg atatattcgc cgctccattc agccatgaga tacttaatcc
      361 tcttcgtcaa taaattgaga ccagaccaca cagttgatgt gggtactgac cgtaaacccg
      421 catagtttac cgtacaggcg ttaccgtgac atcgtgtaat gcacctgtcg gcgtgataat
      481 gcatataatt ttaacggcta tttgggattt gctcaatcta tacgcaaaga agtttagatg
      541 tccagatgta ttgacgtcca ttaacacaat gtttactctg gtgcctgaca tttcaccgac
      601 aaagcccagg gaacttcatc acatgacgcg taaacaggcc accatcgcag tgcgtagcgg
      661 gttaaatgac gacgaacagt atggttgcgt tgtcccaccg atccatcttt ccagcaccta
      721 taactttacc ggatttaatg aaccgcgcgc gcatgattac tcgcgtcgcg gcaacccaac
      781 gcgcgatgtg gttcagcgtg cgctggcaga actggaaggt ggtgctggtg cagtacttac
      841 taataccggc atgtccgcga ttcacctggt aacgaccgtc tttttgaaac ctggcgatct
      901 gctggttgcg ccgcacgact gctacggcgg tagctatcgc ctgttcgaca gtctggcgaa
      961 acgcggttgc tatcgcgtgt tgtttgttga tcaaggcgat gaacaggcat tacgggcagc
     1021 gctggcagaa aaacccaaac tggtactggt agaaagccca agtaatccat tgttacgcgt
     1081 cgtggatatt gcgaaaatct gccatctggc aagggaagtc ggggcggtga gcgtggtgga
     1141 taacaccttc ttaagcccgg cattacaaaa tccgctggca ttaggtgccg atctggtgtt
     1201 gcattcatgc acgaaatatc tgaacggtca ctcagacgta gtggccggcg tggtgattgc
     1261 taaagacccg gacgttgtca ctgaactggc ctggtgggca aacaatattg gcgtgacggg
     1321 cggcgcgttt gacagctatc tgctgctacg tgggttgcga acgctggtgc cgcgtatgga
     1381 gctggcgcag cgcaacgcgc aggcgattgt gaaatacctg caaacccagc cgttggtgaa
     1441 aaaactgtat cacccgtcgt tgccggaaaa tcaggggcat gaaattgccg cgcgccagca
     1501 aaaaggcttt ggcgcaatgt tgagttttga actggatggc gatgagcaga cgctgcgtcg
     1561 tttcctgggc gggctgtcgt tgtttacgct ggcggaatca ttagggggag tggaaagttt
     1621 aatctctcac gccgcaacca tgacacatgc aggcatggca ccagaagcgc gtgctgccgc
     1681 cgggatctcc gagacgctgc tgcgtatctc caccggtatt gaagatggcg aagatttaat
     1741 tgccgacctg gaaaatggct tccgggctgc aaacaagggg taaaaatgag tgtgattgcg
     1801 caggcagggg cgaaaggtcg tcagctgcat aaatttggtg gcagtagtct ggctgatgtg
     1861 aagtgttatt tgcgtgtcgc gggcattatg gcggagtact ctcagcctga cgatatgatg
     1921 gtggtttccg ccgccggtag caccactaac cagttgatta actggttgaa actaagccag
     1981 accgatcgtc tctctgcgca tcaggttcaa caaacgctgc gtcgctatca gtgcgatctg
     2041 attagcggtc tgctacccgc tgaagaagcc gatagcctca ttagcgcttt tgtcagcgac
     2101 cttgagcgcc tggcggcgct gctcgacagc ggtattaacg acgcagtgta tgcggaagtg
     2161 gtgggccacg gggaagtatg gtcggcacgt ctgatgtctg cggtacttaa tcaacaaggg
     2221 ctgccagcgg cctggcttga tgcccgcgag tttttacgcg ctgaacgcgc cgcacaaccg
     2281 caggttgatg aagggctttc ttacccgttg ctgcaacagc tgctggtgca acatccgggc
     2341 aaacgtctgg tggtgaccgg atttatcagc cgcaacaacg ccggtgaaac ggtgctgctg
     2401 gggcgtaacg gttccgacta ttccgcgaca caaatcggtg cgctggcggg tgtttctcgc
     2461 gtaaccatct ggagcgacgt cgccggggta tacagtgccg acccgcgtaa agtgaaagat
     2521 gcctgcctgc tgccgttgct gcgtctggat gaggccagcg aactggcgcg cctggcggct
     2581 cccgttcttc acgcccgtac tttacagccg gtttctggca gcgaaatcga cctgcaactg
     2641 cgctgtagct acacgccgga tcaaggttcc acgcgcattg aacgcgtgct ggcctccggt
     2701 actggtgcgc gtattgtcac cagccacgat gatgtctgtt tgattgagtt tcaggtgccc
     2761 gccagtcagg atttcaaact ggcgcataaa gagatcgacc aaatcctgaa acgcgcgcag
     2821 gtacgcccgc tggcggttgg cgtacataac gatcgccagt tgctgcaatt ttgctacacc
     2881 tcagaagtgg ccgacagtgc gctgaaaatc ctcgacgaag cgggattacc tggcgaactg
     2941 cgcctgcgtc aggggctggc gctggtggcg atggtcggtg caggcgtcac ccgtaacccg
     3001 ctgcattgcc accgcttctg gcagcaactg aaaggccagc cggtcgaatt tacctggcag
     3061 tccgatgacg gcatcagcct ggtggcagta ctgcgcaccg gcccgaccga aagcctgatt
     3121 caggggctgc atcagtccgt cttccgcgca gaaaaacgca tcggcctggt attgttcggt
     3181 aagggcaata tcggttcccg ttggctggaa ctgttcgccc gtgagcagag cacgctttcg
     3241 gcacgtaccg gctttgagtt tgtgctggca ggtgtggtgg acagccgccg cagcctgttg
     3301 agctatgacg ggctggacgc cagccgcgcg ttagccttct tcaacgatga agcggttgag
     3361 caggatgaag agtcgttgtt cctgtggatg cgcgcccatc cgtatgatga tttagtggtg
     3421 ctggacgtta ccgccagcca gcagcttgct gatcagtatc ttgatttcgc cagccacggt
     3481 ttccacgtta tcagcgccaa caaactggcg ggagccagcg acagcaataa atatcgccag
     3541 atccacgacg ccttcgaaaa aaccgggcgt cactggctgt acaatgccac cgtcggtgcg
     3601 ggcttgccga tcaaccacac cgtgcgcgat ctgatcgaca gcggcgatac tattttgtcg
     3661 atcagcggga tcttctccgg cacgctctcc tggctgttcc tgcaattcga cggtagcgtg
     3721 ccgtttaccg agctggtgga tcaggcgtgg cagcagggct taaccgaacc tgacccgcgt
     3781 gacgatctct ctggcaaaga cgtgatgcgc aagctggtga ttctggcgcg tgaagcaggt
     3841 tacaacatcg aaccggatca ggtacgtgtg gaatcgctgg tgcctgctca ttgcgaaggc
     3901 ggcagcatcg accatttctt tgaaaatggc gatgaactga acgagcagat ggtgcaacgg
     3961 ctggaagcgg cccgcgaaat ggggctggtg ctgcgctacg tggcgcgttt cgatgccaac
     4021 ggtaaagcgc gtgtaggcgt ggaagcggtg cgtgaagatc atccgttggc atcactgctg
     4081 ccgtgcgata acgtctttgc catcgaaagc cgctggtatc gcgataaccc tctggtgatc
     4141 cgcggacctg gcgctgggcg cgacgtcacc gccggggcga ttcagtcgga tatcaaccgg
     4201 ctggcacagt tgttgtaatt tcagaaattt aataatgccc ggtactcatg ttttcgggtt
     4261 tatggtttct aatgaaatat attgaattat cataggatta ggccggatta agcgtttacg
     4321 acgaatccgg caagaagcaa taagtacatg gttagtttat atttgcagtc cggtttgctt
     4381 tgcataccgg attttctttt tcttaccatc ctgaagtttt ttcatcttcc ctgatttttc
     4441 ctcaccatca ttggtcattt ttcggttgac gcccttcggc ttttccttca tctttacatc
     4501 tggacgtcta aacggataga tgtgcacaac acaacatata actacaagcg attgatgagg
     4561 taaggtatga gcttttttca cgccagccag cgggatgccc tgaatcagag cctggcagaa
     4621 gtccaggggc agattaacgt ttcgttcgag tttttcccgc cgcgtaccag tgaaatggag
     4681 cagaccctgt ggaactccat cgatcgcctt agcagcctga aaccgaagtt tgtatcggtg
     4741 acctatggcg cgaactccgg cgagcgcgac cgtacgcaca gcattattaa aggcattaaa
     4801 gagcgcactg gtctggaagc ggcaccgcat cttacttgca ttgatgcgac gcccgacgag
     4861 ctgcgcacca ttgcacgcga ctactggaat aacggtattc gtcatatcgt ggcgctgcgt
     4921 ggcgatctgc cgccgggaag tggtaagcca gaaatgtatg cttctgacct ggtgacgctg
     4981 ttaaaagaag tggcagattt cgatatctcc gtggcggcgt atccggaagt tcacccggaa
     5041 gcaaaaagcg ctcaggcgga tttgcttaat ctgaaacgca aagtggatgc cggagccaac
     5101 cgcgcgatta ctcagttctt cttcgatgtc gaaagctacc tgcgttttcg tgaccgctgt
     5161 gtatcggcgg gcattgatgt ggaaattatt ccgggaattt tgccggtatc taactttaaa
     5221 caggcgaaga aatttgccga tatgaccaac gtgcgtattc cggcgtggat ggcgcaaatg
     5281 ttcgacggtc tggatgatga tgccgaaacc cgcaaactgg ttggcgcgaa tattgccatg
     5341 gatatggtga agattttaag ccgtgaagga gtgaaagatt tccacttcta tacgcttaac
     5401 cgtgctgaaa tgagttacgc gatttgccat acgctggggg ttcgacctgg tttataaata
     5461 gtgtggcttt tgtgaaaatc acacagtgat cacaaatttt aaacagagca caaaatgctg
     5521 cctcgaaatg agggcgggaa aataaggtta tcagccttgt tttctccctc attacttgaa
     5581 ggatatgaag ctaaaaccct tttttataaa gcatttgtcc gaattcggac ataatcaaaa
     5641 aagcttaatt aagatcaatt tgatctacat ctctttaacc aacaatatgt aagatctcaa
     5701 ctatcgcatc cgtggattaa ttcaattata acttctctct aacgctgtgt atcgtaacgg
     5761 taacactgta gaggggagca cattgatgag cacgtcagac gatatccata acaccacagc
     5821 cactggcaaa tgcccgttcc atcagggcgg tcacgaccag agtgcggggg cgggcacaac
     5881 cactcgcgac tggtggccaa atcaacttcg tgttgacctg ttaaaccaac attctaatcg
     5941 ttctaaccca ctgggtgagg actttgacta ccgcaaagaa ttcagcaaat tagattacta
     6001 cggcctgaaa aaagatctga aagccctgtt gacagaatct caaccgtggt ggccagccga
     6061 ctggggcagt tacgccggtc tgtttattcg tatggcctgg cacggcgcgg ggacttaccg
     6121 ttcaatcgat ggacgcggtg gcgcgggtcg tggtcagcaa cgttttgcac cgctgaactc
     6181 ctggccggat aacgtaagcc tcgataaagc gcgtcgcctg ttgtggccaa tcaaacagaa
     6241 atatggtcag aaaatctcct gggccgacct gtttatcctc gcgggtaacg tggcgctaga
     6301 aaactccggc ttccgtacct tcggttttgg tgccggtcgt gaagacgtct gggaaccgga
     6361 tctggatgtt aactggggtg atgaaaaagc ctggctgact caccgtcatc cggaagcgct
     6421 ggcgaaagca ccgctgggtg caaccgagat gggtctgatt tacgttaacc cggaaggccc
     6481 ggatcacagc ggcgaaccgc tttctgcggc agcagctatc cgcgcgacct tcggcaacat
     6541 gggcatgaac gacgaagaaa ccgtggcgct gattgcgggt ggtcatacgc tgggtaaaac
     6601 ccacggtgcc ggtccgacat caaatgtagg tcctgatcca gaagctgcac cgattgaaga
     6661 acaaggttta ggttgggcga gcacttacgg cagcggcgtt ggcgcagatg ccattacctc
     6721 tggtctggaa gtagtctgga cccagacgcc gacccagtgg agcaactatt tcttcgagaa
     6781 cctgttcaag tatgagtggg tacagacccg cagcccggct ggcgcaatcc agttcgaagc
     6841 ggtagacgca ccggaaatta tcccggatcc gtttgatccg tcgaagaaac gtaaaccgac
     6901 aatgctggtg accgacctga cgctgcgttt tgatcctgag ttcgagaaga tctctcgtcg
     6961 tttcctcaac gatccgcagg cgttcaacga agcctttgcc cgtgcctggt tcaaactgac
     7021 gcacagggat atggggccga aatctcgcta catcgggccg gaagtgccga aagaagatct
     7081 gatctggcaa gatccgctgc cgcagccgat ctacaacccg accgagcagg acattatcga
     7141 tctgaaattc gcgattgcgg attctggtct gtctgttagt gagctggtat cggtggcctg
     7201 ggcatctgct tctaccttcc gtggtggcga caaacgcggt ggtgccaacg gtgcgcgtct
     7261 ggcattaatg ccgcagcgcg actgggatgt gaacgccgca gccgttcgtg ctctgcctgt
     7321 tctggagaaa atccagaaag agtctggtaa agcctcgctg gcggatatca tagtgctggc
     7381 tggtgtggtt ggtgttgaga aagccgcaag cgccgcaggt ttgagcattc atgtaccgtt
     7441 tgcgccgggt cgcgttgatg cgcgtcagga tcagactgac attgagatgt ttgagctgct
     7501 ggagccaatt gctgacggtt tccgtaacta tcgcgctcgt ctggacgttt ccaccaccga
     7561 gtcactgctg atcgacaaag cacagcaact gacgctgacc gcgccggaaa tgactgcgct
     7621 ggtgggcggc atgcgtgtac tgggtgccaa cttcgatggc agcaaaaacg gcgtcttcac
     7681 tgaccgcgtt ggcgtattga gcaatgactt cttcgtgaac ttgctggata tgcgttacga
     7741 gtggaaagcg accgacgaat cgaaagagct gttcgaaggc cgtgaccgtg aaaccggcga
     7801 agtgaaattt acggccagcc gtgcggatct ggtgtttggt tctaactccg tcctgcgtgc
     7861 ggtggcggaa gtttacgcca gtagcgatgc ccacgagaag tttgttaaag acttcgtggc
     7921 ggcatgggtg aaagtgatga acctcgaccg tttcgacctg ctgtaatctg accccgttca
     7981 gcggctgctt gctggcagtc gctgaacgtt ctttaccagc gtatagtggg cgaacgaaaa
     8041 ctacacactg gatctctcat gtctgccgca ggaaagagca acccactggc aatcagtggc
     8101 ctggttgtgc tcacacttat ctggagttat agctggattt tcatgaagca agtcaccagt
     8161 tacatcggtg ccttcgactt taccgcctta cgctgcattt tcggcgctct cgttttattc
     8221 atcgtccttt tattacgtgg tcgcggaatg cgcccgacac cgtttaaata caccttagcc
     8281 attgccctgt tacaaacctg cgggatggtt ggtctggcgc agtgggcgtt ggtcagcgga
     8341 ggtgcgggga aggtggcgat cctgagctat accatgccgt tctgggtggt gattttcgcc
     8401 gcgttgtttc tcggtgaacg cctgcgacgt gggcaatatt tcgcgattct gattgccgct
     8461 ttcggcttat ttttggtgtt gcagccgtgg caactcgatt tctcttcgat gaaaagtgcc
     8521 atgctggcaa tcctctccgg cgtcagttgg ggggcgagcg cgattgttgc taaacgtctg
     8581 tatgcccgtc atccgcgcgt ggatttattg tcgttaacat cctggcagat gctgtatgcg
     8641 gcgctggtga tgagtgtggt cgctttactg gtgccgcaac gtgaaattga ctggcagccc
     8701 accgtgttct gggcgctggc ctacagtgcg attctggcga cggcactggc gtggagctta
     8761 tggttgtttg tattgaaaaa cttgcctgcc agtattgcca gcttaagcac actggccgtt
     8821 cccgtttgcg gcgtactctt ttcctggtgg ctgctcggcg agaatccggg ggccgttgaa
     8881 ggtagcggta ttgtgctgat tgtgctggca ctggcgctgg tgagccgtaa gaaaaaagaa
     8941 gccgtcagtg taaaaaggat ctgaattttt tcttcatgtg gggcgatctc ttatttaaca
     9001 aaataacgat aatgccccac catccgccag ttaaacagca catcttcttc ctgcgcgcct
     9061 gcgccaatgt tatgtatcac cagcggcgta ccgtcgcggg cgaagccatc tgaaaccacc
     9121 ccaatatgtg ccagcccgtt atccagtcgc caggagacaa tatcgcccgc ttgatagtca
     9181 ctggggttct tgctggtggg gcgtgtttta tcatggcggc taaaccaggt ttccagatta
     9241 ggcacccgac ggtgatcgat gttgctgtcc gagcgcttta acttccattt ttgcgggtac
     9301 tcagcaaaat tcttcgccat atcttcgtga accagtttct gcaaatcgac cttctggctg
     9361 cgcaatgcgc ggatcaccac atcggaacat acaccgcgtt cttgcggaac atcaccgcca
     9421 ggataagtaa gctgcacata cgccggatcg taaaatagcg tgctgccaat ttgctgtctg
     9481 gcaccgtctg cgatggcaag gttggtattg gcctggattt gtaccacggt tggtggaacg
     9541 gcgggagatt ttaaggagtg gctggtaaat gccgttagca ggctgagcag cgccagtgaa
     9601 gctttcatct ggttcgtccg tgaaaataag agtcacagat tcgaccttcc gggctaacga
     9661 ttgttctgta gagaaaatgt ccagaagcgg ataaaaaatt cctgaacaac gtgggagttt
     9721 cagattactg gcacagagtg ccggatgcgg agtgaacgcc ttatccggcc tacaaaagca
     9781 cgcaaattca atatattgca gagattgcgt aggcctgata agcgtagcgc atcaggcaat
     9841 tttgcgttca aactcccgga caagccggga gtttggagta ggttattccc actcttgcag
     9901 gaaacgctga ccgtactggt cggctaccag cagagcggcg taaacctgat ctggcgtcgc
     9961 gccgccaggc atgttgtgaa tggtttcacc ttctgcacat gccgcttctg ccacaattcg
    10021 cattttcgcc gggacatctt ctttaatatc cagttgagcg agagttattg gcaaacctac
    10081 cgcatggcta agggcagcta cggtttcgat ttcctccacc ggcgcatttt ccagaaccag
    10141 ctgcgtcagc gtaccgaatg ccactttttc accgtgataa tagtgatgcg cgtccgggat
    10201 agcggtcagg ccgttatgca ctgcgtgcgc cgcagccaga ccaccacttt caaaaccaac
    10261 accgctcaaa taggtgttcg cttcaatcac gcgctccagc gccggagtca ctacatgctg
    10321 ttcggcagca agcatcgctt tttcgccttc ttccagcagg gtgttgtagc acagttcagc
    10381 cagtgccagc gcagcctggg tgcacttgcc gcccgccatg gtggtcgcgc cgctacgaga
    10441 gcaggcacgc gcttcaaacc aggttgccag cgcatcgccg atacccgccg ctaacagacg
    10501 tgcaggtgcg ccagcgacga ttttggtgtc gacaatgacc atattcgggt tatttggcaa
    10561 cagcagatag cggtcaaact caccctcatc ggtgtagata acagacaatg cgctgcacgg
    10621 tgcatcggta gaggcgatag tcggtgcgat cgctaccgga acacccatga aatgtgccag
    10681 tgctttggca gtatcgaggg tttttccgcc accgataccg agaattgcgc cacactgcgc
    10741 agtctccgcg atgccacgca gacggtcgat ctcattttgc gaacattcac cgccaaacgg
    10801 cgcaatttct actaccagtc cagcatcttt aaagcttttc tcgacagtgg attgagcaaa
    10861 acctaaaaca aatttgtcac ccaccactaa ccagcgttct gccagcggct tcaggtattc
    10921 gcccagacga ttaatcacat cagcgccctg gatgtattta cccggtgatt gaataatgcg
    10981 gtccataatt gctcctttag agatgagtag tgccaaatgc ggcattccag tcgtgttcga
    11041 acttctctat agctgactct accgcagggg tgttgagcat ttgttgcgct acatctaagg
    11101 gcagggtgat ggattcacat cctgccagta aacagtccag cgcctgacgc ggcgttttaa
    11161 agctggctgc cagcaccatg ctttctggcg cgtgcatttc taacagcgtt tgcagctcct
    11221 gaaccgtacg aatgccgtct ccgccctggg catctacgcg gttaacatac ggagcaacgt
    11281 attttgcccc tgccagtgcg gctaataacc cttgtgcggc gctatataca gcagtgccaa
    11341 gtgtagtaat accctctttt ttcagtattt taattgctgc cagaccttcg gaagtcaccg
    11401 ggattttcac cacaataccc ggaatagcgt cgcgcaggcg cttcgcttct tccaccatcc
    11461 cctgcgcgtc gcggctcatg gtctgagcaa acagaatgcc ctcatcacca atcgcttttt
    11521 gcagacgcgg cagcacttcc catatggact ccttgctggc agcgataatg ctcgggttag
    11581 ttgtcacccc ggcaatgggg aatatgcgtg ccagacgttc gacttctgcg acgttagcgg
    11641 tgtccagata cagttccatg atgtttcctt ttacagttcc agttcatgtt gcagcaggct
    11701 ggcgatagcg tcggcagagg cggcgttaac cagcgcgtta cggaattctt cgtgcatgat
    11761 gcggcgagcg aggcgcgaga aaatgcgcat atgctgatcg cccgcagcgt gtttgttcag
    11821 ggttaacata atgatgaatt gcgcttcatc atcgccccag cgcaccggcg cttgcagacg
    11881 cgccacgctg atggtggatt gctcaatgtg ttctgatttg ctgtgtggaa tggcaaaact
    11941 aaagcccaga ccggtagaga aaacggcctc gcgcgcccac aagtcggctt ccagtttacg
    12001 cggatagcgg cagcggcccg ccagcagcag gttatcggtc atgcctttga gcacttcttc
    12061 tttgctgcgc cagtcgcttt ccagtgtgat gcactcggcg gtgaccagcg gtgcgtcttg
    12121 ttgggtcatg cggaattgcg ccagcaggtg ttccacttcc agcgaagtac ggcaggccat
    12181 tgcctggttg agcaacttgc ggcactcacg gctatcaagt tgcgccatcc gagctttcgc
    12241 cgccggaatt gatggtgcgc tcatgctgag ttcatccagc cctaagccga ccagcaacgg
    12301 cagcacggaa cctttcgctc ccagctcacc gcacagacca atccatttgc cctggcgatg
    12361 caccgcttgc acggcgtaat cgagcgcccg caagaatgcc ggattcaggc tgttgtagtg
    12421 acgagtaacc ttagcgttat cgcgatccac cgccagcaga tactgcgtca ggtcattact
    12481 accaatacta aagaaatcaa tctcttcgca gcattgaccg atgatgaaca tcaccgacgg
    12541 cacttccagc atgatgccga gctggatttt ctcatcaaac ggaatgtgtt cgttacgtag
    12601 ttgctgtttg gcttccgcca gtttttcttt cacccataag atctcttcca ttgaggagat
    12661 catcgggatc atgattttca ggctgccgtg agcggaggcg cggaggatcg accgtagctg
    12721 cgtggtaaac aacgacgcgt actcttcata aatacgcacg gcgcgataac cgaggaacgg
    12781 gtttgcctct gcgggaatgt tcagataatc aacgggtttg tcgccgccaa tgtccatagt
    12841 gcgcacaata atgctgcgtc cgttggcgga ttccagcgcc tgacaaaaaa tgttgtacaa
    12901 ctcgctttcg cccggtgcgc tggtgcgatc catatagagc atttcagtgc ggaacaaacc
    12961 aacgccttcc gcaccattgc cgaatgcggc ctgcgcttcc acggagtgag cgatgttagc
    13021 ggcaatttca atgcggatac cgtcagcggt acgggcttgt tgggtcagcc agacacgctg
    13081 ttgctcacgc agggcgtcct gtacgcgggc ttcttgctga taataacgag ctacggcttc
    13141 ccctggctca accacaatcg ccccggcgtt gccgtcgata taaatcgttt gttgctgcca
    13201 cggagtaagg gcatcaatat ccacaccaac cagcgttgga atgttgaacg aacgggcaag
    13261 gatcaccgta tgtgaggtgg tgccgccgct tttgagcaac aatcctttga ggtgattttt
    13321 atccagttcg aggaactggc tgggggtcag ttcatcagcc atacaaatgg cgggctgcgt
    13381 cagtttgccc ggtgccggga agcgttgctc accgtagatt tgctggagta actggaagca
    13441 gacgtcgcgt acgtccaggg cacgttcttg caggtagctg ctgctggaac gggaaaactc
    13501 ttcgcaaaag tgattcgcgc tggcaacaat tgcttcggcg cagcttaatc cggcgctgac
    13561 gcctgccagt aaatgttcgc gcagggaagt atcgccagcc agggatcggt gagcttccag
    13621 aatcgcgctg gtagcaccgt cgctatccag cagacgaaac tcaatgtttt tcagtaccag
    13681 cgtcaggccg ttttccagtg cggattgctc ggcgtcaacg cctttggctg cgggaagatt
    13741 acccagcgca ttgagatcta aagaagagat cggcgtcaga atgccgcctg cactaccgct
    13801 gcacacggtg cgggcgcgga taatttgcgg attcagattg gtcagtgaaa ccggcagtgg
    13861 ttccagttcg tcagatttaa cttccgccag cggcgcatcg cagtggggga attcatcgcg
    13921 cagccattgg cttaaacgct ggtgcgcttc ctgttcgtcg gccccggaaa tcagtaactg
    13981 gcagttatcg cccgccagcg tatcggtgcc aatcagcgca agggcgcttt tggcgttgcc
    14041 cttgcggtca gtgcgcaggt tatgccactc aatttgtgat gaaaaagtat tacacagcgt
    14101 ttcaacgtgg cttgccggac gcgcatgtac gccgttaggt agctcacaaa taaattccac
    14161 aatcagggcc attgcctctc tcccggtacg gttttctgtt tacaggataa gagcgcacgg
    14221 caacggcctg ccatgtgaca aatctgccaa aagctggaca aatgtaatgt aaccgtcaat
    14281 ttgcgacgcg tctcacaaga cgctgttttg cggcatgctt ccggtttatc gcaagttatg
    14341 aggcggatcg catttttgta ctgatattac aaaagtccag taaatggcct ttttatccac
    14401 tgtttgctcc gcctgcgatt gcctattgtt tcctccatca aaaatatgga catgggcttt
    14461 cgcaagcccg ggagcagctt atgaatgagt tggtgcagat cctgaaaaat acccgtcagc
    14521 atttaatgac gggcgtttca cacatgattc ccttcgtggt atcgggcggt attttgctgg
    14581 cggtttccgt catgttgtat ggcaaaggcg cagtgccgga tgccgtagcc gatccaaatc
    14641 tgaaaaaact gtttgatatc ggcgttgcgg gcttgacgct gatggtgcct ttcctcgcag
    14701 cgtacatcgg ttattccatt gcagagcgtt ctgcgctggc tccgtgcgct atcggtgcct
    14761 gggttggtaa cagctttggt gcgggcttct ttggtgcact gatcgccggg attatcggcg
    14821 gcatcgtggt gcattacctg aagaaaattc cggtgcataa agttctgcgc tcggtgatgc
    14881 ctatcttcat tattcctatc gtcggcacac tgattaccgc aggcatcatg atgtggggct
    14941 tgggcgagcc tgtaggggcg ttgaccaaca gcctgactca gtggcttcag gggatgcagc
    15001 agggcagcat tgttatgctg gcggtgatca tgggtctgat gctggcgttc gatatgggcg
    15061 gtccggttaa caaagtggcc tatgccttca tgctgatttg cgttgctcag ggtgtttata
    15121 ccgtggtggc catcgctgcc gtgggtattt gtatcccgcc gctggggatg gggctggcga
    15181 cgctgattgg tcgtaaaaat ttctccgcag aagagcgcga aaccggcaaa gcggcactgg
    15241 tgatgggctg tgttggcgtt actgaagggg cgattccttt cgccgctgcc gatccgctgc
    15301 gtgtcattcc ttccatcatg gtcggttcag tttgtggtgc agtaactgcg gcgctggtcg
    15361 gtgcgcagtg ctatgcaggc tggggtggtc tgattgtgct gccggtggtt gaaggcaagc
    15421 tgggttatat cgcagcagtg gctgtcggag cagtggtgac ggctgtttgt gtgaacgtgc
    15481 tgaaaagtct ggcgcgtaaa aatgggtctt cgactgatga aaaagaagac gacctggatt
    15541 tggattttga aattaattaa ttgaggaacg agccatgacg aaaattattg cagtaaccgc
    15601 atgtccttca ggtgttgccc atacctatat ggcagcagag gcgctggaaa gtgccgcgaa
    15661 agcgaaaggc tgggaagtga aagtagaaac ccaggggtca attggtctgg aaaatgaact
    15721 gactgcggaa gatgtggcga gcgctgatat ggtgattctg accaaagata tcggcatcaa
    15781 gtttgaagag cgttttgctg gcaagaccat cgtgcgcgtc aacatcagcg atgcagtaaa
    15841 acgtgctgac gccattatga gcaaaattga agctcacctg gcgcaaaccg cttaagttct
    15901 tctcccgctc gcaagggcgg gttcgctttc ccacaggagt tcctcatgac gaatcgtatc
    15961 tctcgcctca aaactgcact gtttgccaat acccgtgaaa tctcgctgga gcgggcgctg
    16021 ctttataccg ccagccatcg gcaaaccgaa ggcgaaccgg tgatattgcg ccgggcgaaa
    16081 gcaacagcgt atatccttga acatgttgaa atttcgattc gtgatgaaga actgattgcc
    16141 ggtaaccgca ccgtaaaacc gcgcgccggg attatgtcgc cggaaatgga cccttactgg
    16201 ctgctgaaag agctggatca attcccgacg cgtccgcagg accgctttgc tatcagcgaa
    16261 gaagataaac gtatctaccg tgaagagttg ttcccgtact gggaaaaacg ttcgatgaaa
    16321 gatttcatca acgggcagat gacagatgaa gtaaaagccg cgaccaacac gcagattttc
    16381 agcatcaacc agacggataa aggccagggg cacattatta ttgattaccc acgcctgttg
    16441 aatcacgggc tgggtgagct ggtggcacag atgcagcaac attgtcagca acagccggag
    16501 aatcactttt atcaggccgc gttgttactg ctggaagcct cgcagaaaca cattttgcgt
    16561 tacgccgaac tggcggaaac gatggcggca aactgcacag atgcccagcg tcgcgaagag
    16621 ctgctgacta ttgcagagat ctcccgccat aacgcgcaac ataagccgca gacgttctgg
    16681 caggcgtgcc agttattctg gtacatgaac atcattctgc aatacgaatc caacgccagt
    16741 tcgctatcgt tggggcgctt cgaccagtat atgttgccgt tctatcagac atcattaacc
    16801 cagggcgaag atgcggcgtt cctgaaagaa ctgctcgaat ctttatgggt gaaatgcaac
    16861 gacatcgtgc tgttacgctc caccagtagc gcgcgttatt tcgccggttt cccgaccggc
    16921 tataccgcac tgctcggcgg gttaaccgag aacggacgta gcgcggtgaa cgtgctttcg
    16981 ttcctttgcc ttgacgccta tcaaagcgtg caattaccgc aaccgaacct cggcgtgcgc
    17041 actaacgcct tgatcgacac gccgttcctg atgaaaaccg ccgaaaccat tcgcttcggc
    17101 accggtattc cgcaaatctt taacgatgaa gtggtggtgc cagcgttcct caaccgtggc
    17161 gtttcgctgg aagatgcgcg cgactattcc gtagtgggct gtgtggaatt atctattccc
    17221 ggcagaacct acggcttgca tgacatcgcg atgtttaatc tgctgaaagt gatggaaatc
    17281 tgcctgcatg aaaatgaagg caatgctgcg ctgacttatg aaggtttact ggagcagatc
    17341 cgcgccaaga tcagccacta catcaccctg atggttgagg gcagcaatat ttgtgatatc
    17401 ggccatcgcg actgggcacc tgtaccgctg ctctcatcgt ttatcagcga ttgtctggaa
    17461 aaaggccgcg atattaccga tggcggcgcg cgttataact tctccggcgt acaggggatc
    17521 ggtatcgcca acctgagcga ttctctccat gcgttgaaag ggatggtttt tgagcaacag
    17581 cgtttaagtt ttgacgaatt gctgtcggta ttaaaagcca acttcgcaac gccagaaggc
    17641 gaaaaagtcc gcgctcgctt aattaaccgc ttcgagaaat acggtaacga tatcgacgag
    17701 gtggataaca tcagcgccga actgttgcgc cactactgca aagaagtgga aaaataccag
    17761 aacccgcgcg gcggctactt cacgccggga tcgtataccg tttctgctca cgtcccgttg
    17821 ggatcggtgg ttggcgcgac gccagacggt cgttttgccg gagaacagct ggcagacggc
    17881 ggcttgtcac ccatgctggg ccaggacgca caagggccaa cagcggtact gaagtcagtc
    17941 agtaagctcg ataacacgct gctgtctaac ggtacgttgc tgaacgtgaa attcactccg
    18001 gcgaccctgg aaggtgaagc aggattacgc aaactggccg acttcttacg ggcgtttacc
    18061 cagcttaagt tacaacatat tcagtttaac gtggtgaacg ccgacacgtt gcgggaagcg
    18121 caacagcgcc cacaagatta tgccgggctg gtggtgcgcg ttgccggata cagcgccttc
    18181 tttgtcgaac tgtcgaagga gatccaggat gacatcatcc gccggacagc gcatcagctg
    18241 taacgttgtg gaaacgcgcc gcgatgatgt ggcgcgcatt ttcaacattc agcgttattc
    18301 actgaatgac ggcgagggca ttcgtacggt ggtctttttt aaaggctgtc cgcatctttg
    18361 cccgtggtgt gctaatccgg agtcgatctc cggcaaaatc cagacggtac gcagagaggc
    18421 gaaatgtctg cactgtgcga aatgtttgcg tgatgcggat gaatgcccct ccggggcgtt
    18481 tgaacggatt ggtcgcgata tcagccttga cgctctggaa cgggaagtga tgaaagatga
    18541 cattttcttt cgcacgtccg gcggcggcgt cacgctttct ggcggcgaag tgttaatgca
    18601 ggcggagttt gctacccgtt ttttacagcg actgcggctg tggggtgtgt catgcgccat
    18661 tgaaactgcc ggagacgcac cagccagcaa gctattaccg ctggcgaaat tgtgcgatga
    18721 agtgttgttc gatttaaaaa ttatggacgc gactcaggcg cgggatgtgg tgaagatgaa
    18781 cctgccacgc gtgctggaga atctgcgttt gctggtgagt gagggcgtca acgtgatccc
    18841 gcgtttaccg ctgatccctg gtttcacgct cagccgggag aatatgcagc aggcgctgga
    18901 tgtactgatc ccgctgaata tcaggcagat ccatctgtta ccgtttcatc agtacggcga
    18961 accgaaatac cgcctgctgg ggaaaacatg gtcgatgaaa gaggtgcctg cgccgtcgtc
    19021 agctgatgtg gcaacgatgc gcgaaatggc agaacgggcc ggacttcagg ttaccgtggg
    19081 aggttaaaat ggcatacctg gtggcagtaa ccgcctgcgt aagcggcgtg gcgcatactt
    19141 atatggcggc ggaacggctg gaaaagttgt gcctgttaga gaagtgggga gtcagcattg
    19201 aaactcaggg cgcgctggga acggagaatc gtttagcgga tgaggatatc cgccgggcgg
    19261 atgttgctct gttgattacg gatatcgagc ttgccggtgc cgagcaattt gaacattgcc
    19321 gctatgtgca atgcagcatc tacgcattcc tgcgtgagcc gcagcgggta atgagcgcgg
    19381 tgcgcaaagt gctttctgcg ccgcagcaaa cccatcttat tctggagtag tcggtttttc
    19441 tgtcagttgg ctgtggtact gccggcgata ttccgacggc gagcgttcgg tgtttttacg
    19501 aaacagacgg cagaagtagt tgctgtcgac aaagccgcag gcgtgcgcca cttcttttac
    19561 cttcaggtca tagcctttca ataacgtctt agcgtgctcc agtcgcgtgt gattcaggta
    19621 ttcgttaaaa ccaatggccc ccgttttttg aaacaggtgc gagaggtaat ttggcgaaat
    19681 ataaaacgcc tgtgcaacag attcgcgggt aagcgcggag gcatagcgtt cgtcgatata
    19741 atcgcgaata gcttcaaata gtgcctggct gcgtgaggcg gtctggattt ggctgccaag
    19801 caaatcgcgg cagtggctaa gcaggctggc gacgataagc cttgccgttt gctgctcctg
    19861 cggctgcatt tgcatttcat tgagcgtttg tagcagaaaa gaacctatgc gtgggccgcg
    19921 tcgggcgacg tgttgcttcg ccagattttg atattgtttg ccatcccatt gcacgacgct
    19981 gaagccgagt tgctgtttgc caaacagcac gctaaaggta gtagcggggg cttgccattg
    20041 tggaaaattc cagccaccag caggaacgta cagcacatcg ccgggaacta acgttgctcc
    20101 agcgccggta tcaacaaact caccttccag cacaatttcc agccgtggaa aatcgacctg
    20161 atacgcaaga tcgggcaccg agccgttact gctggcaaag taaatctggc gcagggacag
    20221 cgggccgttg atcaggcggg agagcagata gctgacgtcg tgatacatgt tattccctta
    20281 ggtatgtaga cgggaaaaca gtaactggca ttattaaaaa aggccacctg aaaagtgtgg
    20341 cctgagggga gttcgatgta aacattgcgg cagttgtatt gccggatgtg gcgtaaacgc
    20401 cttatccagc ctaccgccgc gatctgtagg ccggataaga cgcgtcaagc gtcgcatccg
    20461 gcaaatagcg cctggctgat aattactgat tacccacctg atcgccatag ggcagtgtgt
    20521 cgtaatcgat cagtgcgttt ttcttatacg ggttaccaat ccagcgggta gtttctttga
    20581 actgcggatt caccactgaa cgggttggat cgtaaccgtc gtaagataag cccgccaaat
    20641 ctgaccaggt gtggatcagt tccgccaggc tgtatttacg atcaacatcc tgcgagaaat
    20701 cacggggatg agtcgcttgc catttttctg acgtccacag caggaacgga atggtgtaca
    20761 tatgacgcgt cgggttgtcc tcattacgcc cctgagtttt gtgcggcggc gtgtcgtaaa
    20821 cctcttcacc gtggtcagag aaataaacca ggaaaccgtt cgggtttgct gctttaaagt
    20881 ctttaatcag gctggcaacc acatgatcgt tatacaggtt agcgttgtca taatcgttat
    20941 atgactccag ctcttccgcg tttaatcccg gcggaacatg atcggtattg ccatcaaact
    21001 tgccctgatt ttccgggtag cggtatttgt atttgatatg cgtacccagc agatgaacaa
    21061 tgatcagttt cttcggcgca gggtcattca gcacttcctg gaacggcttc agcacgttgg
    21121 tgtcgtattc acgcgcactc tgcgtacgtt gctggttcat gtagtactgc ttgtcggtct
    21181 ggcgcgaaaa taccgtcagc atggtattgc gggcggtcat cgtctgctgg ttggtgatcc
    21241 agaaggtttt ataacccgcc tgtttcatca tgttcatcag cgacggctgc gtcagataca
    21301 gatccgggtt cttttcattg gcaaaggtca gcgcctgttg caggatttca atggtgtacg
    21361 gacgagacgt aactacgtta ttaaacacgg tcagattcgg atcggtttta tgcagcgcat
    21421 ccagctccgg cgtggtttca cgcggataac cgtacagact catgcgtccg cgctgggtcg
    21481 actcgccaat caccagcact aaagtgcgcg gttcgttacc cgattcatct ttgaaattag
    21541 ccagtggcgg caaggcatta ttttcattca gtaactttgt tagcgagttt agttgctgac
    21601 gatactgata atagccggtc aggaattgcc acggtgcggc aggctccata cgcgaggcca
    21661 ggttatccaa cgttttctca aacggcttgt ttttgataaa cgtattcatg gcgatcggat
    21721 gcagaatcaa gccataaagc agggcaaaag agacaacata acgccacggc tttggaatat
    21781 agaccgggcg caggcgtgtc cacagcagaa ctgccaccgc cgtataggcc agcgcgataa
    21841 gcacaatttt caggctgaaa tactggctta aatactcgct ggcttcgttg gtgttggttt
    21901 cgaacatcac aaacagaacg ctctgcgaga actcctgacc gtagatgacg tagtagcaca
    21961 gcgccgccag agaggccgcc catagcacca cgccgattac tgcggcaata attttaatcc
    22021 gcttcggaaa gaggaatacc gggatcaacc acagcgaact gaataacagc gagtcgcgaa
    22081 tgccgttagt gccactataa ccactgatgt aaataatggc ctgtagcaga gtagagaaaa
    22141 accaaaagta gagcagtgcc caacccaggg ctttccagct aaaaagaggt ttagcctgga
    22201 cttctgtgga atgcatagta agaacctgtc ttgaaaaaat atcgccgaat gtaacgacaa
    22261 ttccttaagg atatctgaag gtatattcag aatttgaata aaatgcagac agaaatatat
    22321 tgaaaacgag ggtgttagaa cagaagtatt tcagaaaacc ctcgcgcaaa agcacgaggg
    22381 tttgcagaag aggaagatta gccggtatta cgcatacctg ccgcaatccc ggcaatagtg
    22441 accattaacg cttgttcgac gcgaggatcc ggttcctggc cttctttttc tgcctggcgg
    22501 gagcggtgca gcaactcggc ctgcaatacg ttcagcgggt cggtgtaaat attccgtagc
    22561 tgaatagact ctgcaatcca cggcagatcg gccatcagat gggaatcgtt ggcaatcgcc
    22621 agcaccactt tgatgtcttc ttcttgcagg ttgcgtaact ctttacctaa cggccacagt
    22681 gctttgtcta ccaggcgttg gtcatagtat tccgccagcc acaggtctgc tttggcgaag
    22741 accatctcca gcatgccgag acgcgtcgag aagaatggcc aatcgcggca catagcctcc
    22801 agctcgctct gtttgccgtc ttcgaccact ttttgcagcg ccgtacctgc acccagccag
    22861 gcggggagca tcagacggtt ttgcgtccag gcgaagatcc acggaatggc gcgtagtgac
    22921 tcgacgccgc cggttgggcg acgtttcgcc ggacgtgaac ccaacggcag tttgcccagt
    22981 tcttgttccg gcgtagcgga gcggaagtaa ggcacaaaat ctttgttttc acgtacgtag
    23041 ccgcggtaga catcgcagga gatgactgac agttcatcca taatgcgacg ccagctctct
    23101 ttcggctccg gcggtggcag caggttggct tccagaatcg ccccggtata aagcgacagg
    23161 ctgctgacgg tgatttctgg cagaccatat ttaaagcgga tcatctcgcc ctgttcggtt
    23221 acgcgcaggc cgcctttcag gcttcctggc ggttgtgaca gcagcgccgc atgagcaggt
    23281 gcgccgccgc gaccaatgga accgccgcga ccgtggaaca acgtcagctc aatacccgct
    23341 ttttcgcagg ttttgattaa tgcatcctgt gcctgatatt gcgcccagga agctgccatc
    23401 actcccgcat cttttgctga gtcggaatag ccaatcatca ccatctgttt gccctgaatc
    23461 aggccacgat accagtcaat attgagcagc tgggtcatga catcgttggc gttgttcaga
    23521 tcatcgaggg tttcaaacag cggagcaacc ggcatcgcaa acccgatacc cgcttctttc
    23581 agcagcaggt ggacagccag tacgtcggac ggcgttttcg ccatcgagat cacgtaggcg
    23641 gcaatggagc cttgcggtgc ttcggcaatc acctggcagg tatcgagcac ttcgcgcgtt
    23701 tcggcgcttg gttgccagtt gcgcggcaga agcggacgtt tggagttcag ttcgcggatc
    23761 aggaacgcct gtttgtcggc ctctgaccag ctttcgtagt cgccgatacc gaggtagcgg
    23821 gtcagctcgc ccagcgcttc ggtatgacgc gtgctctcct gacggatatc aatacggacc
    23881 agcggtacgc cgaaacattt cacgcggcgc agggtgtcga gcagatcgcc gttggcgata
    23941 atacccatgc cacacgcctg aagtgactgg tagcaagcgt agagcggttc ccacagttct
    24001 tcgttttgtg tcagcaggcc ttctggtttt ggcagttctt cgcctttcag gcgcgcttcc
    24061 agccatgcct gtgtcgccat caggcgagaa cgcaggtttt tcatcagata gcgatacggt
    24121 tctgcggcac cttcttcgcc aaccagcgcc agcagttcag gggtcgcttc aaccatcgac
    24181 agttcagaaa ccagcacctg aatatctttc aggaacaaat cggtggcttt ccagcggctg
    24241 agtagcagga cgtggcgggt gatatcggca gtgacgttcg ggttgccgtc gcggtcgccg
    24301 cccatccacg aagtaaaacg gaccggaaca aattcgacgg gcagtttgta gccgaggttc
    24361 tcttccagtt gttcgttcag ttcgcgcagg taatttggta cgccttgcca caggctgttt
    24421 tccactacgg caaagcccca tttggcttca tctaccgggc ttggacgcag cttacggatt
    24481 tcatcggtat gccatgactg ggcgatcaac tggcgcaggc gacgcatcag ctggttgtgt
    24541 tcgtagtcag cgatatcttt gttatcgagc tgttttaaac aggcgttcac ttccaccatt
    24601 ttgtggatca gtgtacgacg ggtaatttcg gttgggtgag ccgtgaggac cagttccagc
    24661 gacagcgatt ccactgcttt tttgatggtg tcttcgctca gttccggctg gtttttcagt
    24721 ttacgcaggg tgcgggcgat cacttccggg ttgctggcag cttcgccttt cggcgaaatg
    24781 ctgtggtatt gctcggcggt gttggccagg ttcaggaact gactaaacgc acgcgcaacg
    24841 ggcagcagct cgtcgttcga caaattttgt aaggtggtga gcaactcctg gcggttagca
    24901 tcattgccag cgcgtgaaga tttcgacaac ttacggatag tttctacgcg ttcaagaatg
    24961 tgttctccca acgcatcctt gatggtttct cccagcactt tgccgagcat actgacatta
    25021 ctacgcaatg cggaatattg ttcgttcata ttaccccaga caccccatct tatcgtttga
    25081 tagccctgta tccttcacgt cgcattggcg cgaatatgct cgggctttgc ttttcgtcgt
    25141 cttttataaa gccacgtaaa agcggtgacg tcaaatgctg cgaaatcgct tcagcaaacg
    25201 aataaatagc aggaatttac gtcattaaat tcacgacgct ttaaataagc gtaacttatg
    25261 gaaatgttaa aaaatcgccc caagtaacac caaaggtgta ggtcggataa gatgcgcaag
    25321 tatcgcatcc gacattattg cggcactgga gtttggcaac agtgccggat gcggcgcgag
    25381 cgccttatcc ggcctacagt tgggcatcgt ttgagtcact gtcggtcgga taagatgcgc
    25441 aagtatcgca tccgacatta ttgcggcact ggagtttggc aacagtgccg gatgcggcgc
    25501 gagcgcctta tccggcctac ggttgggcat cgtttgagtc actgtaggtc ggataagatg
    25561 cgcaagcatc gcatccgaca ttattgcggc actggagttt ggcaacagcg ccggatgcgg
    25621 cgcgagcgcc ttatccggcc tacgttttaa tgccagcaaa aatggtgaat tacctgggtt
    25681 atcagttcgc gggtgggctt gataaaccgt gtttccagat attcatcagg ttgatgagcc
    25741 tgattaattg agccaggccc caacaccagc gtcgggcata acgtttgaat aaacggcgct
    25801 tcggtacagt agttcaccac ttcggttttt gctccgagca atttctcaac cacttcaacc
    25861 agttgatgat tcggtgggca ttcatagcca gggatcggcg gatgcagctc gtcgaccgtc
    25921 agacgacccg gccagcgttc gctcaccgga gccaatgcat cgttgagcaa accattaagt
    25981 tcattgagtg tcatgccagg cagcggacga atatccatat gcaactcaca gcaagcgcaa
    26041 atacggttag aagcgtcgcc accgtgaata tgcccgaggt tgagcgtagg gtatggcacg
    26101 gtaaacgctt cgtagtgata acgttctttc aggttatcgc gcaattgcaa aatatgcccg
    26161 atggcgtcgt gcattagttc gatagcgtta actccgcgtg ctggatcgct ggagtgcccc
    26221 gactggccct gaatacggat ggcgttagag atatgacctt tatgtgcgcg taccggttgt
    26281 agtgacgtcg gttcgccaat gatggcgcaa tccgggcgca gggcggtagt ttcggcaaaa
    26341 taacgcgctc cggccatact ggtttcttca tcagcagtcg ccagaatgta gagcggtttt
    26401 ttcagtttcg tgacgtcgac atcgcgtagc gcatcaagga taaacgcaaa aaagcctttc
    26461 atgtcggcgg tgcctaagcc gtaaagcttg ccgtcatgct ccgtcagtgt aaacggatcg
    26521 cgcgtccagc gaccgtcatc aaatggcacc gtatcggtat gccccgccag caacaagccg
    26581 ccagccccct gtccgatact tgccagcata ttgaatttgt tgcgagttcc tggaacaggc
    26641 tgcacttcca cattgaagcc caaatcttta aaccagtccg ccagcagagt gattaaatct
    26701 gcattgcttt gatcgagtgc ctcttccgtg gcgcttattg aaggtgtggc aatcagagcg
    26761 cggtaaatct cgataaatgg cggtaatttg tttttcattg ttgacacacc tctggtcatg
    26821 atagtatcaa tattcatgca gtatttatga ataaaaatac actaacgttg agcgtaataa
    26881 aacccaccag ccgtaaggtg aatgttttac gtttaacctg gcaaccagac ataagaaggt
    26941 gaatagcccc gatgttgaat acgctgattg tgggtgccag cggctacgct ggcgcagagc
    27001 tagtgaccta tgtaaatcgc catccgcata tgaacataac cgctttgact gtttcagcgc
    27061 aaagcaatga tgcgggaaag ttaatctccg atttgcatcc gcagctaaaa ggcatcgttg
    27121 atctgccgtt gcagccgatg tcggatatca gcgagtttag cccaggggtg gacgtagtgt
    27181 ttctcgccac cgcccatgaa gttagccacg atttagcgcc gcagtttctt gaagcgggct
    27241 gcgtggtgtt cgacctttcc ggcgcgtttc gtgttaacga cgccaccttc tatgaaaaat
    27301 attacggctt tacccatcaa tacccggaac tgttggaaca ggcagcctac ggtctggcgg
    27361 agtggtgcgg taataaatta aaagaagcga atttgattgc ggtgccgggc tgttatccga
    27421 cggcggcaca gctggcgctg aaaccgttga ttgatgccga tcttcttgac ctcaatcagt
    27481 ggccggtgat caacgccacc agcggcgtga gcggtgcagg gcgtaaagcg gccatttcaa
    27541 acagcttttg tgaagttagc ctgcaaccgt atggcgtctt tactcatcgc catcaaccag
    27601 agatcgccac acacctcggt gctgacgtta tcttcacccc acatctgggc aatttcccgc
    27661 gcggcattct cgaaaccatt acctgccgcc tgaaatcggg tgtgacccag gcgcaagtcg
    27721 cgcaagtgtt acagcaggcg tatgcccata aaccgctggt gcggctgtat gacaaaggcg
    27781 ttccggcgct gaaaaatgtc gttgggctgc cattttgcga tatcgggttt gccgttcagg
    27841 gcgagcatct gattattgtg gcgaccgaag acaacttact gaaaggcgcg gcggcacaag
    27901 cggtacagtg cgccaatatt cgtttcggct atgcggaaac gcagtctctt atttaagggt
    27961 gcaatgatga atccattaat tatcaaactg ggcggcgtac tgctggatag tgaagaggcg
    28021 ctggaacgtc tgtttagcgc actggtgaat tatcgtgagt cacatcagcg tccgctggtg
    28081 attgtgcacg gcggcggttg cgtggtggat gagctgatga aagggctgaa tctgccggtg
    28141 aaaaagaaaa acggcctgcg ggtgacgcct gctgatcaga tagacattat caccggagca
    28201 ctggcgggaa cggcaaataa aaccctgttg gcatgggcga agaaacatca gattgcggcc
    28261 gtaggtttgt ttctcggtga cggcgacagc gtcaaagtga cccagcttga tgaagagtta
    28321 ggtcatgttg gactggcgca gctaggttcg cctaagctta tcaactcctt gctggagaac
    28381 ggttatctgc cggtggtcag ctccattggc gtaacagacg aagggcaact gatgaacgtc
    28441 aatgccgacc aggcggcaac ggcgctggcg gcaacgctgg gcgcggatct gattttgctc
    28501 tccgacgtca gcggcattct cgacggcaaa gggcaacgca ttgccgaaat gaccgccgcg
    28561 aaagcagaac aactgattga gcagggcatt attactgacg gcatgatagt gaaagtgaac
    28621 gcggcgctgg atgcggcccg cacgctgggc cgtccggtag atatcgcctc ctggcgtcat
    28681 gcggagcagc ttccggcact gtttaacggt atgccgatgg gtacgcggat tttagcttaa
    28741 gttttgttgg ccggaggcgc agctttccgg cattgaattt caaaataagg aaacagagtt
    28801 atggcacttt ggggcgggcg ttttacccag gcagcagatc aacggttcaa acaattcaac
    28861 gactcactgc gctttgatta ccgtctggcg gagcaggata ttgttggctc tgtggcctgg
    28921 tccaaagccc tggtcacggt aggcgtgtta accgcagaag agcaggcgca actggaagag
    28981 gcgctgaacg tgttgctgga agatgttcgc gccaggccac aacaaatcct tgaaagcgac
    29041 gccgaagata tccatagctg ggtggaaggc aaactgatcg acaaagtggg ccagttaggc
    29101 aaaaagctgc ataccgggcg tagccgtaat gatcaggtag cgactgacct gaaactgtgg
    29161 tgcaaagata ccgttagcga gttactgacg gctaaccggc agctgcaatc ggcgctggtg
    29221 gaaaccgcac aaaacaatca ggacgcggta atgccaggtt acactcacct gcaacgcgcc
    29281 cagccggtga cgttcgcgca ctggtgcctg gcctatgttg agatgctggc gcgtgatgaa
    29341 agccgtttgc aggatgcgct taagcgtctg gatgtcagcc cgctaggctg tggcgcgctg
    29401 gcgggaacgg cctatgaaat cgaccgtgaa cagttagcag gctggctggg ctttgcttcg
    29461 gcgacccgta acagtctcga cagcgtttct gaccgtgacc atgtgttgga actgctttct
    29521 gctgccgcta tcggcatggt gcatctgtcg cgttttgctg aagatctgat tttctttaac
    29581 accggcgaag cggggtttgt ggagctttct gaccgcgtga cttccggttc atcattaatg
    29641 ccgcagaaga aaaacccgga tgcgctggag ctgattcgcg gtaaatgcgg ccgggtgcag
    29701 ggggcgttaa ccggcatgat gatgacgctg aaaggtttgc cgctggctta caacaaagat
    29761 atgcaggaag acaaagaagg tctgttcgac gcgctcgata cctggctgga ctgcctgcat
    29821 atggcggcgc tggtgctgga cggcattcag gtgaaacgtc cacgttgcca ggaagcggct
    29881 cagcagggtt acgccaacgc caccgaactg gcggattatc tggtggcgaa aggcgtaccg
    29941 ttccgcgagg cgcaccatat tgttggtgaa gcggtggtgg aagccattcg tcagggcaaa
    30001 ccgctggaag atctgccgct cagtgagttg cagaaattca gtcaggtgat tgacgaagat
    30061 gtctatccga ttctgtcgct gcaatcgtgc ctcgacaagc gtgcggcaaa aggcggcgtc
    30121 tcaccgcagc aggtggcgca ggcgattgct tttgcgcagg ctcggttagg gtaagaacat
    30181 ttatatgtat aaatttgagc ctggcttatc gccgggcttt tttatggcaa aaaaaagcgg
    30241 atcctggaga tccgcaaaag ttcacgttgg ctttagttat tcgagttgag aaactctcga
    30301 aacgggcagt gacttcaagg gttaaaagag gtgccgctcc gtttctgtga gcaattatca
    30361 gtcagaatgc ttgataggga taatcgttca ttgctattct acctatcgcc atgaactatc
    30421 gtggcgatgg aggatggata atgaatattc gtgatcttga gtacctggtg gcattggctg
    30481 aacaccgcca ttttcggcgt gcggcagatt cctgccacgt tagccagccg acgcttagcg
    30541 ggcaaattcg taagctggaa gatgagctgg gcgtgatgtt gctggagcgg accagccgta
    30601 aagtgttgtt cacccaggcg ggaatgctgc tggtggatca ggcgcgtacc gtgctgcgtg
    30661 aggtgaaagt ccttaaagag atggcaagcc agcagggcga gacgatgtcc ggaccgctgc
    30721 acattggttt gattcccaca gttggaccgt acctgctacc gcatattatc cctatgctgc
    30781 accagacctt tccaaagctg gaaatgtatc tgcatgaagc acagacccac cagttactgg
    30841 cgcaactgga cagcggcaaa ctcgattgcg tgatcctcgc gctggtgaaa gagagcgaag
    30901 cattcattga agtgccgttg tttgatgagc caatgttgct ggctatctat gaagatcacc
    30961 cgtgggcgaa ccgcgaatgc gtaccgatgg ccgatctggc aggggaaaaa ctgctgatgc
    31021 tggaagatgg tcactgtttg cgcgatcagg caatgggttt ctgttttgaa gccggggcgg
    31081 atgaagatac acacttccgc gcgaccagcc tggaaactct gcgcaacatg gtggcggcag
    31141 gtagcgggat cactttactg ccagcgctgg ctgtgccgcc ggagcgcaaa cgcgatgggg
    31201 ttgtttatct gccgtgcatt aagccggaac cacgccgcac tattggcctg gtttatcgtc
    31261 ctggctcacc gctgcgcagc cgctatgagc agctggcaga ggccatccgc gcaagaatgg
    31321 atggccattt cgataaagtt ttaaaacagg cggtttaaac cgtttaacgc agctacccga
    31381 taggcttccg ccatcgtcgg gtagttaaag gtggtgttga cgaagtactc aatagtgttg
    31441 ccgccacctt tctgttccat aatcgcctga ccgatatgaa taatttcggc agcgcgctcg
    31501 ccaaagcagt gaatacccag aatctctttt gtttcccgat ggaacaaaat tttcagcgtg
    31561 cccacgttca tgccgacgat ttgtgcgcgt gccagatgtt taaactgggc gcggcccact
    31621 tcatatggca ctttcattgc ggtcagctgc tgttcggttt tgcccacaga gctgatttcc
    31681 gggatggtgt aaataccggt agggatatct tcaatcagat gtgcggtggc ttcgcctttt
    31741 accagcgcct gcgcggcaat gcgcccctgg tcataggccg ccgacgccag gctcggataa
    31801 ccaatcacgt cgcccaccgc gtaaacgtgt ggctgtgcgg tctgatacat gctgttgacc
    31861 ttcagctgtc cgcggctgtc agtttctagc ccaatgttct gtaacgccag cgaatcggta
    31921 ttaccggtgc gaccgttggc atagagcagg cagtcagctt tcagtttttt acccgacttc
    31981 agatgcatga tcacaccatc gtcacagcct tcgatcttct cgtactcttc gttgtgacga
    32041 atcactacgc cactgttcca gaagtgatag gagagagaat ctgacatctc ttgatcgaga
    32101 aatgccagca ggcgatcgcg ggtgttgatc agatccactt ttacatccat accgcggaag
    32161 atcgacgcat attcacagcc gatcactcca gcaccataga taagtacatg gcgcggttcg
    32221 tggtgcatgc tgagaattga gtcgctgtcg taaatgcgtg gatgggtgaa atcaacatct
    32281 gttggatgat atggacgaga gccgcaggca ataacaaatt tttcagcggt tagtgtttca
    32341 acgctgccgt ccgggcaatc cagcgccaac gtatgctcgt caacaaagcg agcgtttccc
    32401 tgcaatattt cacagtgatt acgttcgtaa aatccctgac gcatgcgcgt ttgttgatta
    32461 atcacgttat cggcatggtt aaggatatcg gcaaaagaag agcggagcag tcgggaatgg
    32521 tcgctgtaaa gtgggttttg attgaattct ataatgcggc tgacggcgtg acggagagct
    32581 ttcgacggga tggtgcccca gtgggtgcaa ccgccgccaa cattttgata acgctcgata
    32641 actgcgacgc gcgcaccttg cttaaccagg cccattgcag cgccttcgcc gccggggccg
    32701 gaacctatta ctatggcatc gtaatcgtag gaatgtggca tggtagggct tacctgttct
    32761 tatacataaa agcaacagaa tggtaacatt ttatcgcggg taagccaatt gatccccgtc
    32821 atttatctgg ctatatcctg agcggccttt gctttgtctg tttcttactt ttgccctgac
    32881 gttttattgg atttttatcg acgatactct ccgtttaagc ggcaggtttc cgctgtacgt
    32941 aaaagaaccg gccaaagaat tgcagtaaat atgttttatt gcgttaccgt tcattcacaa
    33001 tactggagca atccagtatg ttcattctct ggtatagtgc cagcagtatt tttggcaagg
    33061 attcagacat cgtgatgggc gtaagagcgc aacaaaaaga aaaaacccgc cgttcgctgg
    33121 tggaagccgc atttagccaa ttaagtgctg aacgcagctt cgccagcctg agtttgcgtg
    33181 aagtggcgcg tgaagcgggc attgctccca cctcttttta tcggcatttc cgcgacgtag
    33241 acgaactggg tctgaccatg gttgatgaga gcggtttaat gctacgccaa ctcatgcgcc
    33301 aggcgcgtca gcgtatcgcc aaaggcggga gtgtgatccg cacctcggtc tccacattta
    33361 tggagttcat cggtaataat cctaacgcct tccggttatt attgcgggaa cgctccggca
    33421 cctccgctgc gtttcgtgcc gccgttgcgc gtgaaattca gcacttcatt gcggaacttg
    33481 cggactatct ggaactcgaa aaccatatgc cgcgtgcgtt tactgaagcg caagccgaag
    33541 caatggtgac aattgtcttc agtgcgggtg ccgaggcgtt ggacgtcggc gtcgaacaac
    33601 gtcggcaatt agaagagcga ctggtactgc aactgcgaat gatttcgaaa ggggcttatt
    33661 actggtatcg ccgtgaacaa gagaaaaccg caattattcc gggaaatgtg aaggacgagt
    33721 aatgaaacaa gcaaatcaag atagaggtac gctgctgctg gcgttagttg ctggcttatc
    33781 gattaatggt actttcgcag cgctgtttag ctccattgtg ccattttctg tattcccgat
    33841 tatttccctg gtgctgacgg tttactgcct gcatcaacgt tatcttaatc gcactatgcc
    33901 ggtaggcttg ccgggtctgg cagctgcctg ttttattctc ggcgtactgc tgtacagcac
    33961 ggtagttcgt gcggaatatc cggatatcgg ctctaacttc ttcccggcag tactctccgt
    34021 cattatggtg ttctggattg gcgcgaagat gcgtaaccgt aagcaggaag ttgctgagta
    34081 atcggtatta tgccggatgc tggcgcatcc ggcatgggtt ttacttcgcg gtcagtaata
    34141 cgccgcactc catatggtgc gtgtagggga actgatcaaa cagagccaga cgttcgacct
    34201 tgtgcgtctg gcttaatgtt tccagattct tgcataacgt ttccgggtta caggagatgt
    34261 acaaaatacg cggatacgcc tgcaccattt tctcggtttc actgtccaga ccgctgcgcg
    34321 gtgggtcgac aaaaatggtt tcgcactgat aactctttaa gtcgatccct tgcaggcggt
    34381 taaactcgcg cacaccattc atcgcctgag taaattcttc tgccgccata cgaataattt
    34441 gtacgttatc aatatggtta gctgcgatgt tgtattgcgc agcagcaacc gacggcttag
    34501 cgatttcggt ggctaatacc cgatcaaaat tacgcgccag cgctaatgaa aagttaccgt
    34561 tgccgcagta cagctccagt aaatcgcctt ttgagccttt ggttacgtcc agcgcccatt
    34621 ccagcatctg aatattcatc gccgcgttcg gctgggtaaa gctgttttct acctgacggt
    34681 agatcatctc tttccctgcg accggcagac gttcatcgat gtaatcctga tccagctcga
    34741 ttttggtttt cgttgcccga ccaatcagat gcacattcag attctgcgcg cgcagtgcat
    34801 cgcgcagggc ctccgcttcc tgacgccact catcatccag cttcttatgg tatagcaggg
    34861 aaaccaccgc ctgattactc agcgtagtga ggtaatcaat ctggaacaac ttgtggcgca
    34921 gaacgggatt attacgcaca cccgcaatca tcgccgtcat caactggttg ataagttcac
    34981 tggcggcggg gaagctatcc acgcggatgc ggcttttggt ttgttgatcg aaaatgatgt
    35041 gatacaggtc atcgccatcg tgccagatgc ggaactccgc gcgcatccgg taatgactga
    35101 ccggcgagcg aaacacttcc ggaaccaggt cagaaaacgg tgccatcata ctttgcaaac
    35161 gtaccacttt ttcggctaac tgcgcttcat actgttctgt tggaaggtgt tcgggggtca
    35221 tgatgtatcc tgaaaaatta aagtacgcgg cgattgtagg gattgctcat cagatgtcca
    35281 gatcttgatg aattcctatt tgtgagctac gtctggacag taacttgtta caacctgtag
    35341 catccacttg ccggtcctgt gagttaatag ggaatccagt gcgaatctgg agctgacgcg
    35401 cagcggtaag gaaaggtgcg atgattgcgt tatgcggaca ctgccattcg gtgggaagtc
    35461 atcatctctt agtatcttag atacccctcc aagcccgaag acctgccggc caacgtcgca
    35521 tctggttctc atcatcgcgt aatattgatg aaacctgcgg catccttctt ctattgtgga
    35581 tgctttacaa tgattaaaaa agcttcgctg ctgacggcgt gttccgtcac ggcattttcc
    35641 gcttgggcac aggataccag cccggatact ctcgtcgtta ctgctaaccg ttttgaacag
    35701 ccgcgcagca ctgtgcttgc accaaccacc gttgtgaccc gtcaggatat cgaccgctgg
    35761 cagtcgacct cggtcaatga tgtgctgcgc cgtcttccgg gcgtcgatat cacccaaaac
    35821 ggcggttcag gtcagctctc atctattttt attcgcggta caaatgccag tcatgtgttg
    35881 gtgttaattg atggcgtacg cctgaatctg gcgggggtga gtggttctgc cgaccttagc
    35941 cagttcccta ttgcgcttgt ccagcgtgtt gaatatatcc gtgggccgcg ctccgctgtt
    36001 tatggttccg atgcaatagg cggggtggtg aatatcatca cgacgcgcga tgaacccgga
    36061 acggaaattt cagcagggtg gggaagcaat agttatcaga actatgatgt ctctacgcag
    36121 caacaactgg gggataagac acgggtaacg ctgttgggcg attatgccca tactcatggt
    36181 tatgatgttg ttgcctatgg taataccgga acgcaagcgc agacagataa cgatggtttt
    36241 ttaagtaaaa cgctttatgg cgcgctggag cataacttta ctgatgcctg gagcggcttt
    36301 gtgcgcggct atggctatga taaccgtacc aattatgacg cgtattattc tcccggttca
    36361 ccgttgctcg atacccgtaa actctatagc caaagttggg acgccgggct gcgctataac
    36421 ggcgaactga ttaaatcaca actcattacc agctatagcc atagcaaaga ttacaactac
    36481 gatccccatt atggtcgtta tgattcgtcg gcgacgctcg atgagatgaa gcaatacacc
    36541 gtccagtggg caaacaatgt catcgttggt cacggtagta ttggtgcggg tgtcgactgg
    36601 cagaaacaga ctacgacgcc gggtacaggt tatgttgagg atggatatga tcaacgtaat
    36661 accggcatct atctgaccgg gctgcaacaa gtcggcgatt ttacctttga aggcgcagca
    36721 cgcagtgacg ataactcaca gtttggtcgt catggaacct ggcaaaccag cgccggttgg
    36781 gaattcatcg aaggttatcg cttcattgct tcctacggga catcttataa ggcaccaaat
    36841 ctggggcaac tgtatggctt ctacggaaat ccgaatctgg acccggagaa aagcaaacag
    36901 tgggaaggcg cgtttgaagg cttaaccgct ggggtgaact ggcgtatttc cggatatcgt
    36961 aacgatgtca gtgacttgat cgattatgat gatcacaccc tgaaatatta caacgaaggg
    37021 aaagcgcgga ttaagggcgt cgaggcgacc gccaattttg ataccggacc actgacgcat
    37081 actgtgagtt atgattatgt cgatgcgcgc aatgcgatta ccgacacgcc gttgttacgc
    37141 cgtgctaaac agcaggtgaa ataccagctc gactggcagt tgtatgactt cgactggggt
    37201 attacttatc agtatttagg cactcgctat gataaggatt actcatctta tccttatcaa
    37261 accgttaaaa tgggcggtgt gagcttgtgg gatcttgcgg ttgcgtatcc ggtcacctct
    37321 cacctgacag ttcgtggtaa aatagccaac ctgttcgaca aagattatga gacagtctat
    37381 ggctaccaaa ctgcaggacg ggaatacacc ttgtctggca gctacacctt ctgaaccacg
    37441 tcccaccgtg ctggtgtttg actccggcgt cggtgggttg tcggtctatg acgagatccg
    37501 gcatctctta ccggatctcc attacattta tgctttcgat aacgtcgctt tcccgtatgg
    37561 cgaaaaaagc gaagcgttta ttgttgagcg agtggtggca attgtcaccg cggtgcaaga
    37621 acgttatccc cttgcgctgg ctgtggtcgc ttgcaacact gccagtaccg tttcacttcc
    37681 tgcattacgc gaaaagttcg acttcccggt tgttggtgtc gtgccggcga ttaaacctgc
    37741 tgcacgtctg acggcaaatg gcattgtcgg attactggca acccgcggaa cagttaaacg
    37801 ttcttatact catgagctga tcgcgcgttt cgctaatgaa tgccagatag aaatgctggg
    37861 ctcggcagag atggttgagt tggctgaagc gaagctacat ggcgaagatg tttctctgga
    37921 tgcactaaaa cgtatcctac gcccgtggtt aagaatgaaa gagccgccag ataccgttgt
    37981 attgggttgc acccatttcc ctctactaca agaagaactg ttacaagtgc tgccagaggg
    38041 aacccggctg gtggattctg gcgcagcgat tgctcgccga acggcctggt tgttagaaca
    38101 tgaagccccg gatgcaaaat ctgccgatgc gaatattgcc ttttgtatgg caatgacgcc
    38161 aggagctgaa caattattgc ccgttttaca gcgttacggc ttcgaaacgc tcgaaaaact
    38221 ggcagtttta ggctgatttg gttgaatg
//
LOCUS       DAPOAV010000039        37974 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.039, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000039 DAPOAV010000000
VERSION     DAPOAV010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37974
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.039"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(363..1283)
                     /gene="malM"
                     /locus_tag="RN951_002261"
     CDS             complement(363..1283)
                     /gene="malM"
                     /locus_tag="RN951_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose operon protein MalM"
                     /protein_id="HDX2527252.1"
                     /translation="MKMNKSLIVLCLSAGLLASAPGISLADVNYVPQNTSDAPAIPSA
                     ALQQLTWTPVDQSKTQTTQLATGGQQLNVPGISGPVAAYSVPANIGELTLTLTSEVNK
                     QTSVFAPNVLILDQNMTPSAFFPSSYFTYQEPGVMSADRLEGVMRLTPALGQQKLYVL
                     VFTTEKDLQQTTQLLDPAKAYAKGVGNSIPDIPDPVARHTTDGLLKLKVKTNSSSSVL
                     VGPLFGSSAPAPVTVGNTAAPAVAAPAPAPVKKSEPMLNDTESYFNTAIKNAVAKGDV
                     DKALKLLDEAERLGSTSARSTFISSVKGKG"
     gene            complement(1526..2866)
                     /gene="lamB"
                     /locus_tag="RN951_002262"
     CDS             complement(1526..2866)
                     /gene="lamB"
                     /locus_tag="RN951_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltoporin LamB"
                     /protein_id="HDX2527253.1"
                     /translation="MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGE
                     QQCFQTTGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVAQQNDWEAT
                     DPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDVG
                     FGKLSLAATRSSEAGGSSSFASNNIYDYTNETANDVFDVRLAQMEINPGGTLELGVDY
                     GRANLRDNYRLVDGASKDGWLFTAEHTQSVLKGFNKFVVQYATDSMTSQGKGLSQGSG
                     VAFDNEKFAYNINNNGHMLRILDHGAISMGDNWDMMYVGMYQDINWDNDNGTKWWTVG
                     IRPMYKWTPIMSTVMEIGYDNVESQRTGDKNNQYKITLAQQWQAGDSIWSRPAIRVFA
                     TYAKWDEKWGYDYTGNADNNANFGKAVPADFNGGSFGRGDSDEWTFGAQMEIWW"
     gene            complement(2938..4053)
                     /gene="malK"
                     /locus_tag="RN951_002263"
     CDS             complement(2938..4053)
                     /gene="malK"
                     /locus_tag="RN951_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011915502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter ATP-binding
                     protein MalK"
                     /protein_id="HDX2527254.1"
                     /translation="MASVQLQNVTKAWGEVVVSKDINLDIHEGEFVVFVGPSGCGKST
                     LLRMIAGLETITSGDLFIGEKRMNDTPPAERGVGMVFQSYALYPHLSVAENMSFGLKL
                     AGAKKEVINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEP
                     LSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKP
                     LELYHYPADRFVAGFIGSPKMNFLPVKVTATAIDQVQVELPMPNRQQVWLPVESRDVQ
                     VGANMSLGIRPEHLLPSDIADVILEGEVQVVEQLGNETQIHIQIPSIRQNLVYRQNDV
                     VLVEEGATFAIGLPPERCHLFREDGTACRRLHKEPGV"
     gene            4418..5608
                     /gene="malE"
                     /locus_tag="RN951_002264"
     CDS             4418..5608
                     /gene="malE"
                     /locus_tag="RN951_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter
                     substrate-binding protein MalE"
                     /protein_id="HDX2527255.1"
                     /translation="MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYN
                     GLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLL
                     AEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPA
                     LDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGL
                     TFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTF
                     KGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYE
                     EELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQT
                     RITK"
     gene            5762..7306
                     /gene="malF"
                     /locus_tag="RN951_002265"
     CDS             5762..7306
                     /gene="malF"
                     /locus_tag="RN951_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalF"
                     /protein_id="HDX2527256.1"
                     /translation="MDVIKKKHWWQSDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAI
                     TTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTF
                     ERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLK
                     ETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGT
                     LTNNQSGVKYRPNNQIGFYQSITADGNWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKP
                     FLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVLLILPYAVPSFISIL
                     IFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLL
                     KAIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNG
                     GPDRLGTTTPAGYTDLLVNYTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAIVNLKA
                     TRMKFD"
     gene            7321..8211
                     /gene="malG"
                     /locus_tag="RN951_002266"
     CDS             7321..8211
                     /gene="malG"
                     /locus_tag="RN951_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001252048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalG"
                     /protein_id="HDX2527257.1"
                     /translation="MAMVQPKSQKARLFITHLLLLLFIAAIMFPLLMVVAISLRQGNF
                     ATGSLIPEQISWDHWKLALGFSVEQADGRITPPPFPVLLWLWNSVKVAGISAIGIVAL
                     STTCAYAFARMRFPGKATLLKGMLIFQMFPAVLSLVALYALFDRLGEYIPFIGLNTHG
                     GVIFAYLGGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVV
                     FILSFIAAITEVPVASLLLRDVNSYTLAVGMQQYLNPQNYLWGDFAAAAVMSALPITI
                     VFLLAQRWLVNGLTAGGVKG"
     gene            8583..10058
                     /gene="xylE"
                     /locus_tag="RN951_002267"
     CDS             8583..10058
                     /gene="xylE"
                     /locus_tag="RN951_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose transporter XylE"
                     /protein_id="HDX2527258.1"
                     /translation="MNTQYNSSYIFSITLVATLGGLLFGYDTAVISGTVESLNTVFVA
                     PQNLSESAANSLLGFCVASALIGCIIGGALGGYCSNRFGRRDSLKIAAVLFFISGVGS
                     AWPELGFTSINPDNTVPVYLAGYVPEFVIYRIIGGIGVGLASMLSPMYIAELAPAHIR
                     GKLVSFNQFAIIFGQLLVYCVNYFIARSGDASWLNTDGWRYMFASECIPALLFLMLLY
                     TVPESPRWLMSRGKQEQAEGILRKIMGNTLATQAVQEIKHSLDHGRKTGGRLLMFGVG
                     VIVIGVMLSIFQQFVGINVVLYYAPEVFKTLGASTDIALLQTIIVGVINLTFTVLAIM
                     TVDKFGRKPLQIIGALGMAIGMFSLGTAFYTQAPGIVALLSMLFYVAAFAMSWGPVCW
                     VLLSEIFPNAIRGKALAIAVAAQWLANYFVSWTFPMMDKNSWLVAHFHNGFSYWIYGC
                     MGVLAALFMWKFVPETKGKTLEELEALWEPETKKTQQTATL"
     gene            complement(10102..10512)
                     /gene="psiE"
                     /locus_tag="RN951_002268"
     CDS             complement(10102..10512)
                     /gene="psiE"
                     /locus_tag="RN951_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible protein PsiE"
                     /protein_id="HDX2527259.1"
                     /translation="MTSLSRPRVEFISTILQTVLNLGLLCLGLILVVFLGKETVHLAD
                     VLFAPEQTSKYELVEGLVVYFLYFEFIALIVKYFQSGFHFPLRYFVYIGITAIVRLII
                     VDHKSPLDVLIYSAAILLLVITLWLCNSKRLKRE"
     gene            complement(10638..10781)
                     /locus_tag="RN951_002269"
     CDS             complement(10638..10781)
                     /locus_tag="RN951_002269"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527260.1"
                     /translation="MFQRNIVDFSRIAGGWESPEWVIFELPALVRFVLPDAPPGAAYP
                     AYG"
     gene            10782..11060
                     /locus_tag="RN951_002270"
     CDS             10782..11060
                     /locus_tag="RN951_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527261.1"
                     /translation="MKRNLIKVVKMKPYFAALMLSVSVLPAYAGPLGTADKADLPQSN
                     VSSPMMAQSLRQPDLQPISTDRKTECFRLYTPDRKPGVNCVPDGSTGH"
     gene            complement(11107..13203)
                     /locus_tag="RN951_002271"
     CDS             complement(11107..13203)
                     /locus_tag="RN951_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbH domain-containing protein"
                     /protein_id="HDX2527262.1"
                     /translation="MKKRHLLSLLALGISTACYGETYPAPIGPSQSDFGGVGLLQTPT
                     ARMAREGELSLNYRDNDQYRYYSASVQLFPWLETTLRYTDVRTRQYSSVEAFSGDQTY
                     KDKAFDLKLRLWEESYWLPQVAVGARDIGGTGLFDAEYLVASKAWGPFDFTLGLGWGY
                     LGTSGNVKNPLCSASDKYCYRDNSYKQAGSIDGSQMFHGPASLFGGVEYQTPWQPLRL
                     KLEYEGNNYQQDFAGKLEQKSKFNVGAIYRVTDWADVNLSYERGNTFMFGVTLRTNFN
                     DLRPSYNDNARPQYQPQPQDAILQHSVVANQLTLLKYNAGLADPQIQAKGDTLYVTGE
                     QVKYRDSREGIIRANRIVMNDLPDGIKTIRITENRLNMPQVTTETDVASLKNHLAGEP
                     LGHETTLAQKRVEPVVPQSTEQGWYIDKSRFDFHIDPVLNQSVGGPENFYMYQLGVMG
                     TADLWLTDHLLTTGSLFANLANNYDKFNYTNPPQDSHLPRVRTHVREYVQNDVYVNNL
                     QANYFQHLGNGFYGQVYGGYLETMFGGAGAEVLYRPLDSNWAFGLDANYVKQRDWRSA
                     KDMMKFTDYSVKTGHLTAYWTPSFAQDVLVKASVGQYLAGDKGGTLEIAKRFDSGVVV
                     GGYATITNVSKEEYGEGDFTKGVYVSVPLDLFSSGPTRSRAAIGWTPLTRDGGQQLGR
                     KFQLYDMTSDRSVNFR"
     gene            complement(13203..13940)
                     /locus_tag="RN951_002272"
     CDS             complement(13203..13940)
                     /locus_tag="RN951_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule biosynthesis GfcC family protein"
                     /protein_id="HDX2527263.1"
                     /translation="MIKQTIVALLLSVGASSVFAAGTVKVFSNGSSEAKTLTGAEHLI
                     DLVGQPRLANSWWPGAVISEELATAAALRQQQALLTRLAEQGADSSADDAAAINALRQ
                     QIQALKVTGRQKINLDPDIVRVAERGNPPLQGNYTLWVGPPPSTVTLFGLISRPGKQP
                     FTPGRDVASYLSDQSLLSGADRSYAWVVYPDGRTQKAPVAYWNKRHVEPMPGSIIYVG
                     LADSVWSETPDALNADILQTLTQRIPQ"
     gene            complement(13937..14575)
                     /locus_tag="RN951_002273"
     CDS             complement(13937..14575)
                     /locus_tag="RN951_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418451.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbF family lipoprotein"
                     /protein_id="HDX2527264.1"
                     /translation="MKRPALILICLLLQACSATTKELGNSLWDSLFGTPGVQLTDDDI
                     QNMPYASQYMQLNGGPQLFVVLAFAEDGQQKWVTQDQATLVTQHGRLVKTLLGGDNLI
                     EVNNLAADPLIKPAQIVDGASWTRTMGWTEYQQVRYATARSVFKWDGTDTVKVGSDET
                     PVRVLDEEVSTDQARWHNRYWIDSEGQIRQSEQYLGADYFPVKTTLIKAAKQ"
     gene            complement(14689..14931)
                     /locus_tag="RN951_002274"
     CDS             complement(14689..14931)
                     /locus_tag="RN951_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527265.1"
                     /translation="MKKVLYGIFAISALAATSAWAAPVQVGEAAGSAATSVSAGSSSA
                     TSVSTVSSAVGVALAATGGGDGSNTGTTTTTTTSTQ"
     gene            complement(15430..17079)
                     /gene="pgi"
                     /locus_tag="RN951_002275"
     CDS             complement(15430..17079)
                     /gene="pgi"
                     /locus_tag="RN951_002275"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HDX2527266.1"
                     /translation="MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSAT
                     FDDQMLVDYSKNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALR
                     NRSNTPILVDGKDVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDL
                     GPYMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTN
                     AHSARDWFLKAAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSA
                     IGLSIVLSIGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEA
                     ILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLI
                     HQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKD
                     PATLDYVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQW
                     GVELGKQLANRILPELKDDKEISSHDSSTNGLINRYKAWRG"
     gene            17604..18953
                     /gene="lysC"
                     /locus_tag="RN951_002276"
     CDS             17604..18953
                     /gene="lysC"
                     /locus_tag="RN951_002276"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-sensitive aspartokinase 3"
                     /protein_id="HDX2527267.1"
                     /translation="MSEIVVSKFGGTSVADFDAMNRSADIVLSDANVRLVVLSASAGI
                     TNLLVALAEGLEPGERFEKLDAIRNIQFAILERLRYPNVIREEIERLLENITVLAEAA
                     ALATSPALTDELVSHGELMSTLLFVEILRERDVQAQWFDVRKVMRTNDRFGRAEPDIA
                     ALAELAALQLLPRLNEGLVITQGFIGSENKGRTTTLGRGGSDYTAALLAEALHASRVD
                     IWTDVPGIYTTDPRVVSAAKRIDEIAFAEAAEMATFGAKVLHPATLLPAVRSDIPVFV
                     GSSKDPRAGGTLVCNKTENPPLFRALALRRNQTLLTLHSLNMLHSRGFLAEVFGILAR
                     HNISVDLITTSEVSVALTLDTTGSTSTGDTLLTQSLLMELSALCRVEVEEGLALVALI
                     GNDLSKACGVGKEVFGVLEPFNIRMICYGASSHNLCFLVPGEDAEQVVQKLHSNLFE"
     gene            19206..19478
                     /locus_tag="RN951_002277"
     CDS             19206..19478
                     /locus_tag="RN951_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3811 domain-containing protein"
                     /protein_id="HDX2527268.1"
                     /translation="MALPRITQKEMTEREQRELKTLLDRARIAHGRVLTNSETNSIKK
                     DYIDKLMVEREAEAKKARQLKKKQAYKPDPEASFSWSANTSTRGRR"
     gene            complement(19611..20483)
                     /gene="rluF"
                     /locus_tag="RN951_002278"
     CDS             complement(19611..20483)
                     /gene="rluF"
                     /locus_tag="RN951_002278"
                     /EC_number="5.4.99.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2604) synthase RluF"
                     /protein_id="HDX2527269.1"
                     /translation="MLPDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRATIGD
                     QVKPGDVVKVNGQLIEPREAEDLVLIALNKPVGIVSTTEDGERDNIVDFVNHSKRVFP
                     IGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITEEFIRGMSAGVPIL
                     GTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPL
                     GEWRDLTDDELIDLFKLIENSSSEVKPKAKAKPKTAGIKRPVVKMEKTAEKGGRPASN
                     GKRFTSPGRKKKGR"
     gene            20695..21384
                     /gene="pepE"
                     /locus_tag="RN951_002279"
     CDS             20695..21384
                     /gene="pepE"
                     /locus_tag="RN951_002279"
                     /EC_number="3.4.13.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepE"
                     /protein_id="HDX2527270.1"
                     /translation="MELLLLSNSTLPGKAWLEHALPLIAEQLQGRRSAVFIPFAGVTQ
                     TWDDYTAKTAAVLAPLGVSVTGIHSVVDPVAAIENAEIVIVGGGNTFQLLKQCRERGL
                     LAPITDVVKRGALYIGWSAGANLACPTIRTTNDMPIVDPQGFDALNLFPLQINPHFTN
                     ALPEGHKGETREQRIRELLVVAPELTIIGLPEGNWITVSKGHATLGGPNTTYVFKAGE
                     EAVPLEAGHRF"
     gene            complement(21475..23106)
                     /locus_tag="RN951_002280"
     CDS             complement(21475..23106)
                     /locus_tag="RN951_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDX2527271.1"
                     /translation="MLTLLHLLSAVALLVWGTHIVRTGVMRVFGARLRTVLSRSVEKK
                     PLAFCAGIGVTALVQSSNATTMLVTSFVAQDLVALAPALVIVLGADVGTALMARILTF
                     DLSWLSPLLIFIGVIFFLGRKQSRAGQLGRVGIGLGLILLALELIVQAVTPITQANGV
                     QVIFASLTGDILLDALIGAMFAIISYSSLAAVLLTATLTAAGIISFPVALCLVIGANL
                     GSGLLAMLNNSAANAAARRVALGSLLFKLVGSLIILPFVHLLAETMGKLSLPKAELVI
                     YFHVFYNLVRCLVMLPFVDPMARFCKTIIRDEPELDTQLRPKHLDVSALDTPTLALAN
                     AARETLRIGDAMEQMMEGLNKVMHGEPRQEKELRKLADDINVLYTAIKLYLARMPKEE
                     LAEEESRRWAEIIEMSLNLEQASDIVERMGSEIADKSLAARRAFSLDGLKELDALYEQ
                     LLSNLKLAMSVFFSGDVTSARRLRRSKHRFRILNRRYSHAHVDRLHQQNVQSIETSSL
                     HLGLLGDMQRLNSLFCSVAYSVLEQPDEDEGRDEY"
     gene            complement(23326..27009)
                     /gene="metH"
                     /locus_tag="RN951_002281"
     CDS             complement(23326..27009)
                     /gene="metH"
                     /locus_tag="RN951_002281"
                     /EC_number="2.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HDX2527272.1"
                     /translation="MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLNEADFRGERFAD
                     WPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYQMESLSAE
                     INFAAAKLARACADEWTARTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDGLV
                     AAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKTEFEALGVELPIMISGTITDA
                     SGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAG
                     LPNAFGEYDLDADTMAKQIREWAQAGFLNIVGGCCGTTPQHIAAMSRAVEGLAPRKLP
                     EIPVACRLSGLEPLNIGEDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVE
                     NGAQIIDINMDEGMLDAEAAMVRFLNLIAGEPDIARVPIMIDSSKWDVIEKGLKCIQG
                     KGIVNSISMKEGVDAFIHHAKLLRRYGAAVVVMAFDEQGQADTRARKIEICRRAYKIL
                     TEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVS
                     FSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRR
                     DDGTERLLELAEKYRGSKTDDTANAQQAEWRSWEVNKRLEYSLVKGITEFIEQDTEEA
                     RQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASK
                     EQGKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNA
                     DLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVY
                     VQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPRTPPVTLEAARDNDF
                     AFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVE
                     AQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLR
                     QQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMV
                     KALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYPACPEHT
                     EKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYA
                     RRKGMSVTEVERWLAPNLGYDAD"
     gene            27209..28033
                     /gene="iclR"
                     /locus_tag="RN951_002282"
     CDS             27209..28033
                     /gene="iclR"
                     /locus_tag="RN951_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418442.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate bypass operon transcriptional
                     repressor IclR"
                     /protein_id="HDX2527273.1"
                     /translation="MVAPIPAKRGRKPAVATAPATGQVQSLTRGLKLLEWIAESNGSV
                     ALTELAQQAGLPNSTTHRLLTTMQQQGFVRQVGELGHWAIGAHAFMVGSSFLQSRNLL
                     AIVHPILRNLMEESGETVNMAVLDQSDHEAIIIDQVQCTHLMRMSAPIGGKLPMHASG
                     AGKAFLAQLSEEQVTKLLHRKGLHAYTHATLVSPVHLKEDLAQTRKRGYSFDDEEHAL
                     GLRCLAACIFDEHREPFAAISISGPISRITDDRVTEFGAMVIKAAKEVTLAYGGMR"
     gene            28350..30536
                     /gene="espL4"
                     /locus_tag="RN951_002283"
     CDS             28350..30536
                     /gene="espL4"
                     /locus_tag="RN951_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector EspL4"
                     /protein_id="HDX2527274.1"
                     /translation="MITRIPRSSFSANINNTAQTNEHQTLSELFYKELEDKFSGKELA
                     TPLLKSFSENCRQNGRHIFSNKDFVIKFSTSVLQADKKEITIINKNENTTLTQTIAPI
                     FEKYLMEILPQRSDTLDKQELNLKSDRKEKEFPRIKLNGQCYFPGRPQNRIVCRHIAA
                     QYINDIYQNVDYKPHQDDYSSAEKFLTHFNKKCKNQTLALVSSRPEGRCVAACGDFGL
                     VMKAYFDKMESNGISVMAAILLVDNHALTVRLRIKNTTEGCTHYVVSVYDPNVTNDKI
                     RIMSESKENIKHYSLMDFMNVDYSLLKWSNDHVINQSVAIIPALPKEQLLMLKGSVDE
                     ITPPLSPATMNLLMAIGQNHQLTQLMIQLQKMPELHRTEMLTAYNSINLPGLYLAINY
                     GNADIVETIFNSLSETGYEGLLSKKNLMHILEAKDKNGFSGLFLAISRKDKNVVTSIL
                     NALPKLAATHHLDNEQVYKFLSAKNRTSSHVLYHVMANGDADMLKIVLNALPLLIRTC
                     HLTKEQVLDLLKAKDFYGCPGLYLAMQNGHSDIVKVILEALPSLAQEINISASDIVDL
                     LTAKSLARDTGLFMAMQRGHMNVINTIFNALPTLFNTFKFDKKNMKPLLLANNSNEYP
                     GLFSAIQHKQQNVVETVYLALSDHARLFGFTAEDIMDFWQHKAPQKYSAFELAFEFGH
                     RVIAELILNTLNKMAESFGFTDNPRYIAEKNYMEALLKKASPHTVR"
     gene            complement(30505..32241)
                     /gene="aceK"
                     /locus_tag="RN951_002284"
     CDS             complement(30505..32241)
                     /gene="aceK"
                     /locus_tag="RN951_002284"
                     /EC_number="2.7.11.5"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional isocitrate dehydrogenase
                     kinase/phosphatase"
                     /protein_id="HDX2527275.1"
                     /translation="MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQ
                     QAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESF
                     FNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDL
                     PLRLRWQNKSRDIHYIIRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITPSG
                     TLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILP
                     GKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRV
                     FKVIKDRFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMEL
                     LLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAA
                     ANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSV
                     SPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRR
                     QRFSVRYGEMLF"
     gene            complement(32522..33826)
                     /gene="aceA"
                     /locus_tag="RN951_002285"
     CDS             complement(32522..33826)
                     /gene="aceA"
                     /locus_tag="RN951_002285"
                     /EC_number="4.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate lyase"
                     /protein_id="HDX2527276.1"
                     /translation="MKTRTQQIEELQKEWTQPRWEGITRPYSAEDVVKLRGSVNPECT
                     LAQLGAAKMWRLLHGESKKGYINSLGALTGGQALQQAKAGIEAVYLSGWQVAADANLA
                     ASMYPDQSLYPANSVPAVVERINNTFRRADQIQWSAGIEPGDPRYVDYFLPIVADAEA
                     GFGGVLNAFELMKAMIEAGAAAVHFEDQLASVKKCGHMGGKVLVPTQEAIQKLVAARL
                     AADVTGVPTLLVARTDADAADLITSDCDPYDSEFITGERTSEGFFRTHAGIEQAISRG
                     LAYAPYADLVWCETSTPDLELARRFAQAIHAKYPGKLLAYNCSPSFNWQKNLDDKTIA
                     SFQQQLSDMGYKFQFITLAGIHSMWFNMFDLANAYAQGEGMKHYVEKVQQPEFAAAKD
                     GYTFVSHQQEVGTGYFDKVTTIIQGGTSSVTALTGSTEESQF"
     gene            complement(33856..35457)
                     /gene="aceB"
                     /locus_tag="RN951_002286"
     CDS             complement(33856..35457)
                     /gene="aceB"
                     /locus_tag="RN951_002286"
                     /EC_number="2.3.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate synthase A"
                     /protein_id="HDX2527277.1"
                     /translation="MTEQATTTDELAFTRPYGEQEKQILTAEAVEFLTELVTHFTPQR
                     NKLLAARIQQQQDIDNGTLPDFISETASIRDADWKIRGIPADLEDRRVEITGPVERKM
                     VINALNANVKVFMADFEDSLAPDWNKVIDGQINLRDAVNGTISYTNEAGKIYQLKPNP
                     AVLICRVRGLHLPEKHVTWRGEAIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQS
                     WQEAAWWSEVFSYAEDRFNLPRGTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGR
                     WDYIFSYIKTLKNYPDRVLPDRQAVTMDKPFLNAYSRLLIKTCHKRGAFAMGGMAAFI
                     PSKDEEHNNQVLNKVKADKSLEANNGHDGTWIAHPGLADTAMAVFNDILGSRKNQLEV
                     MREQDAPITADQLLAPCDGERTEEGMRANIRVAVQYIEAWISGNGCVPIYGLMEDAAT
                     AEISRTSIWQWIHHQKTLSNGKPVTKALFRQMLGEEMKVIASELGEERFSQGRFDDAA
                     RLMEQITTSDELIDFLTLPGYRLLA"
     gene            complement(35726..36655)
                     /gene="metA"
                     /locus_tag="RN951_002287"
     CDS             complement(35726..36655)
                     /gene="metA"
                     /locus_tag="RN951_002287"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HDX2527278.1"
                     /translation="MPIRVPDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLM
                     PKKIETENQFLRLLSNSPLQVDIQLLRIDSRESRNTPAEHLNNFYCNFEDIQDQNFDG
                     LIVTGAPLGLVEFNDVAYWPQIKQVLEWSKDHVTSTLFVCWAVQAALNILYGIPKQTR
                     TDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGD
                     AYLFASKDKRIAFVTGHPEYDAQTLAQEFFRDVEAGLDPDVPYNYFPHNDPQNTPRAS
                     WRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD"
     gene            36812..37255
                     /locus_tag="RN951_002288"
     CDS             36812..37255
                     /locus_tag="RN951_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDX2527279.1"
                     /translation="MVISIRRSRHEEGEELVAIWCRSVDATHDFLSAEYRTELEDLVR
                     SFLPEAPLWVAVNERDQPVGFMLLSGQHMDALFIDPDVRGCGVGRVLVEHALSMAPEL
                     TTNVNEQNEQAVGFYKKVGFKVTGRSEVDDLGKPYPLLNLAYVGA"
     gene            complement(37318..37701)
                     /locus_tag="RN951_002289"
     CDS             complement(37318..37701)
                     /locus_tag="RN951_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527280.1"
                     /translation="MSVLYIQIRRNQITVRDLESKREVSGDAAFSNQRLLIANFFVAE
                     KVLQDLVLQLHPRSTWHSFLPAKRMDIVVSALEMNEGGLSQVEERILHEVVAGATLMK
                     YRQFHIHAQSAVLSDSAVMAMLKQK"
     gene            complement(37778..37893)
                     /gene="rrf"
                     /locus_tag="RN951_002290"
     rRNA            complement(37778..37893)
                     /gene="rrf"
                     /locus_tag="RN951_002290"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         9120 a         9825 c         9587 g         9442 t
ORIGIN      
        1 aagttatctc tgtttaaacc tggcacccca tttaaattac gtagtaaatc aagatctact
       61 atattatttc cttgcaccac atcatgtttc atcaaagagt tattgccgcc agaatttagg
      121 atatgactta tcataaaacc tctgcataac agaaataaaa taacctggaa aagtagcctg
      181 aatgtccaga cactaccggc gaaagaaaaa gaatctctga taaggcattg agataatgga
      241 tattcttagt gaagaagaag tgagttacta taaaaaatcg ctcatatccc aggaaggaag
      301 cataaaaaaa ggtgcgccag gagacgcacc agttgttgca aaatcagcac tgtggggcgt
      361 aattacccct tgccttttac actgctgata aaggtggaac gggcagatgt cgatcccagg
      421 cgttcagctt catcaagcag ttttaacgcc ttatcaacat cacctttcgc gacagcgttt
      481 ttgatcgcgg tattaaaata actttccgtg tcgttgagca tcggctcgct tttcttcacc
      541 ggtgccggag cgggtgcagc cacagctggt gccgccgtgt tacctaccgt aaccggagct
      601 ggagcggaag aaccaaataa aggtcctacc aacacgctgg agctggagtt cgttttcact
      661 ttcagtttca gtaagccatc ggtggtatga cgagcaaccg gatcggggat atccgggatc
      721 gagttaccga cgcccttggc ataggcttta gccgggtcga gcagttgggt cgtctgctgg
      781 agatcttttt ccgtggtaaa gaccagaaca taaagttttt gctgccccaa cgccggtgtc
      841 aggcgcataa cgccttccag ccgatctgca ctcatcacgc ctggttcctg gtaggtgaaa
      901 taactgctgg ggaagaaggc tgatggggtc atgttctgat caagaatcag cacgttcggc
      961 gcaaaaacgc tggtttgttt gttcacttcg ctggtcagcg tcagggtcag ttcgccaatg
     1021 tttgccggga cgctgtacgc agcaaccgga ccactgatgc cgggaacgtt cagttgttgg
     1081 ccgccggtcg ccagttgggt ggtctgggtt ttagattgat cgaccggtgt ccaggtgagt
     1141 tgttgcagcg cagcagatgg aatggctggc gcgtcgctgg tgttttgcgg tacgtagtta
     1201 acatcggcaa ggctaattcc aggcgcgctt gccagtaacc ctgctgataa acagaggacg
     1261 atgagacttt tattcatttt cattgttttc acctcaaaat ctggagctca gcggtagcca
     1321 ggcaatagcg cgctaaaccc gataatcaga ggggctttcg cccctttcag ataatgacaa
     1381 cctgttttta tgccggatgc ggcgtaaacg ccttatccgg cctacatttg acagccgttg
     1441 taggcctgat aagacgcgca agcgtcgcat caggcgttgg ttgccgaatg cggcgtaaac
     1501 gccttatccg gcccaggttt tgctattacc accagatttc catctgggca ccgaaggtcc
     1561 actcgtcgct gtcgccacga ccgaagctgc cgccgttgaa atcagcagga acggctttgc
     1621 cgaagttcgc gttgttatca gcgttaccgg tgtagtcgta accccatttc tcatcccact
     1681 tggcgtaggt tgcgaagaca cgaatagccg ggcgtgacca gatgctgtcg ccagcctgcc
     1741 attgttgtgc gagggtaatt ttgtactgat tgttcttgtc gccggtgcgc tgggattcga
     1801 cgttgtcgta gccgatttcc atcacggtgc tcatgattgg cgtccacttg tacatcgggc
     1861 gaataccgac ggtccaccac ttggtgccgt tgtcgttatc ccagttgata tcctggtaca
     1921 tacccacgta catcatgtcc cagttgtcgc ccatggagat cgcaccgtgg tcgaggatac
     1981 gcagcatgtg accgttgttg ttgatattgt aggcaaattt ttcgttatca aatgcaacgc
     2041 cagaaccctg cgacagccct ttaccctgcg aggtcatcga gtcagtagcg tactgaacaa
     2101 caaacttgtt aaagcccttc aggacactct gagtatgttc agcagtgaat aaccagccgt
     2161 ctttcgatgc gccatcaacc agacgatagt tatcacgcaa gttggcacga ccgtagtcga
     2221 cacccagttc taatgtgccg cccgggttga tttccatctg cgctaaacgc acatcgaaaa
     2281 cgtcgttcgc ggtttcgttg gtatagtcat aaatattgtt gctggcgaaa gaggaagaac
     2341 caccagcttc agaggagcgg gttgctgcca gagagagttt accgaagcca acatcgatgt
     2401 tttccagacc ggcaccagga ccagaaatat cccagtagta gaagtcgatc atatgaacgt
     2461 catgacgttg gtagaagcgc ttacctgccc agatggtgga gcctggcagc cattcgatca
     2521 ggtttttacc ctgcacgttt gcttcacgga aggccggatc ggtagcttcc cagtcattct
     2581 gttgtgcgac ggaataggcc acgttagtgt cgaaatagaa gctcttatcg ccctctttcc
     2641 acacttcctg acccaatttt aattcagcat aagtttcaca ttcgttgcca agacggtatt
     2701 tactttgagc accggtagtc tggaaacact gttgttcacc gccgctacct gtccaaccaa
     2761 taccggaacg tgcatagccg tggaaatcaa cagccattgc ctgagcagac attacgcccg
     2821 ctgcgacggc aaccgccaga ggaagtttgc gcagagtaat catcattcta tctcctgagt
     2881 cattgctttt cttttttcac atcacctgtg acaggctttg tgtgttttgt ggggtgctta
     2941 aacgcccggc tccttatgca gtcgacgaca tgcagtgcca tcctcacgga acagatggca
     3001 acgctctggc ggcaggccga tagcgaatgt ggcaccttct tctaccaaca ccacgtcgtt
     3061 ctggcggtac accaggtttt gacgaatgga agggatctgg atatggattt gagtttcgtt
     3121 gccgagttgc tcgacgacct gaacttcacc ctcaaggatg acgtcagcga tatcactcgg
     3181 cagtagatgt tccgggcgaa tacccagcga catattggct ccaacctgga catcacggct
     3241 ttcaactggc agccagactt gctgacgatt tggcatcggc agctccacct gcacttgatc
     3301 gattgcggtg gcggtcactt ttaccggcag gaagttcatc tttggcgaac cgataaatcc
     3361 ggcgacaaaa cggtctgccg gatagtggta cagctccagc ggtttcccaa cctgcgccac
     3421 gcgaccggcg tccagcacca cgattttgtc ggccagcgtc atcgcttcga cctgatcgtg
     3481 ggtgacgtaa atcattgtgc ggcccaggcg tttatgcaga cgggagattt cgatacgcat
     3541 ttgcacacgc agtgcagcat cgaggttgga gagcggttca tcgagcaaaa atacgcttgg
     3601 ctcggccacc agcgtacggc caatcgccac acgctgacgc tgaccaccgg agagcgcttt
     3661 cggtttgcga tccagcaaat gcgccagttg tagcacttcc gccacctggt taacgcgttg
     3721 gttaatcacc tctttttttg cgccagccag tttcaggcca aatgacatgt tttctgctac
     3781 tgacaggtgg ggatagagcg cgtaagactg aaacaccata ccaacgccgc gttctgctgg
     3841 cggagtgtca ttcatccgtt tctcaccgat gaacaggtcg ccgctggtga tcgtctcaag
     3901 cccggcaatc atgcgcagta aagtcgattt accgcagcca gacggtccga caaacaccac
     3961 gaattcacct tcatggatat cgagattgat atctttcgat accacgacct cgccccaggc
     4021 tttcgttaca ttttgcagct gtacgctcgc catgcccttc tccctttgta acaacctgtc
     4081 atcgacagca acattcatga tgggctgact atgcgtcatc aggagatggc ttaaatcctc
     4141 caccccctgg cttttttatg ggggaggagg cgggaggatg agaacacggc ttctgtgaac
     4201 taaaccgagg tcatgtaagg aatttcgtga tgttgcttgc aaaaatcgtg gcgattttat
     4261 gtgcgcatct ccacattacc gccaattctg taacagagat cacacaaagc gacggtgggg
     4321 cgtaggggca aggaggatgg aaagaggttg ccgtataaag aaactagagt ccgtttaggt
     4381 gttttcacga gcacttcacc aacaaggacc atagattatg aaaataaaaa caggtgcacg
     4441 catcctcgca ttatccgcat taacgacgat gatgttttcc gcctcggctc tcgccaaaat
     4501 cgaagaaggt aaactggtaa tctggattaa cggcgataaa ggctataacg gtctcgctga
     4561 agtcggtaag aaattcgaga aagataccgg aattaaagtc accgttgagc atccggataa
     4621 actggaagag aaattcccac aggttgcggc aactggcgat ggccctgaca ttatcttctg
     4681 ggcacacgac cgctttggtg gctacgctca atctggcctg ttggctgaaa tcaccccgga
     4741 caaagcgttc caggacaagc tgtatccgtt tacctgggat gccgtacgtt acaacggcaa
     4801 gctgattgct tacccgatcg ctgttgaagc gttatcgctg atttataaca aagatctgct
     4861 gccgaacccg ccaaaaacct gggaagagat cccggcgctg gataaagaac tgaaagcgaa
     4921 aggtaagagc gcgctgatgt tcaacctgca agaaccgtac ttcacctggc cgctgattgc
     4981 tgctgacggg ggttatgcgt tcaagtatga aaacggcaag tacgacatta aagacgtggg
     5041 cgtggataac gctggcgcga aagcgggtct gaccttcctg gttgacctga ttaaaaacaa
     5101 acacatgaat gcagacaccg attactccat cgcagaagct gcctttaata aaggcgaaac
     5161 agcgatgacc atcaacggcc cgtgggcatg gtccaacatc gacaccagca aagtgaatta
     5221 tggtgtaacg gtactgccga ccttcaaggg tcaaccatcc aaaccgttcg ttggcgtgct
     5281 gagcgcaggt attaacgccg ccagtccgaa caaagagctg gcgaaagagt tcctcgaaaa
     5341 ctatctgctg actgatgaag gtctggaagc ggttaataaa gacaaaccgc tgggtgccgt
     5401 agcgctgaag tcttacgagg aagagttggc gaaagatcca cgtattgccg ccaccatgga
     5461 aaacgcccag aaaggtgaaa tcatgccgaa catcccgcag atgtccgctt tctggtatgc
     5521 cgtgcgtact gcggtgatca acgccgccag cggtcgtcag actgtcgatg aagccctgaa
     5581 agacgcgcag actcgtatca ccaagtaatg ctgtgaaatg ccggatgcgg cgtgaacgcc
     5641 ttgtccggcc tacaaaaccg aaacgtatgt aggcctgata agacgcgtca gcgtcgcatc
     5701 aggcagttgt tgtcggataa ggcgtgaaag ccttatccgt cctggaatga ggaagaaccc
     5761 catggatgtc attaaaaaga aacattggtg gcaaagcgac gcgctgaaat ggtcagtgct
     5821 aggtctgctc ggcctgctgg tgggttacct tgttgtttta atgtacgcac aaggggaata
     5881 cctgttcgcc attaccacgc tgatattgag ttcagcgggg ctgtatattt tcgccaatcg
     5941 taaagcctac gcctggcgct atgtttaccc gggaatggct ggaatgggat tattcgtcct
     6001 cttccctctg gtctgcacca tcgccattgc cttcaccaac tacagcagca ctaaccagct
     6061 gacttttgaa cgtgcgcagg aagtgttgtt agatcgctcc tggcaagcag gcaaaaccta
     6121 taactttggt ctttacccgg cgggcgatga gtggcaactg gcgctcagcg acggcgaaac
     6181 cggcaaaaat tacctctccg acgcttttaa atttggcggc gagcaaaaac tgcaactgaa
     6241 agaaacgacc gcccagcccg aaggcgaacg cgcgaatctg cgcgtgatta cccagaatcg
     6301 tcaggcgctg agtgacatta ccgccattct gccggatggc aacaaagtga tgatgagctc
     6361 cctgcgccag ttttctggca cgcagccgct ctacacactc gacggtgacg gcacgttgac
     6421 gaataatcag agcggcgtga aatatcgtcc gaataaccaa attggctttt accagtccat
     6481 taccgccgac ggcaactggg gtgatgaaaa gctaagcccc ggttacaccg tgaccaccgg
     6541 ctggaaaaac tttacccgcg tctttaccga cgaaggcatt cagaaaccgt tcctcgccat
     6601 tttcgtctgg accgtggtgt tctcgctgat cactgtcttt ttaacggtgg cggtcggcat
     6661 ggttctggcg tgtctggtgc agtgggaagc gttgcgcggc aaagcggtct atcgcgtcct
     6721 gctgattctg ccctacgcgg tgccatcgtt catttcaatc ttgattttca aagggttgtt
     6781 taaccagagc ttcggtgaaa tcaacatgat gttgagcgcg ctgtttggcg tgaagcccgc
     6841 ctggttcagc gatccgacca ccgcccgcac gatgctaatt atcgtcaata cctggctggg
     6901 ttatccgtac atgatgatcc tctgcatggg cttgctgaaa gcgattccgg acgatttgta
     6961 tgaagcctca gcaatggatg gcgcaggtcc gttccagaac ttctttaaga ttacgctgcc
     7021 gctgctgatt aaaccgctga cgccgctgat gatcgccagc ttcgccttta actttaacaa
     7081 cttcgtgctg attcaactgt taaccaacgg cggcccggat cgtcttggca cgaccacgcc
     7141 agccggttat accgacctgc ttgttaacta cacctaccgc atcgcttttg aaggcggcgg
     7201 gggtcaggac ttcggtctgg cggcagcaat tgccacgctg atcttcctgc tggtgggtgc
     7261 gctggcgata gtgaacctga aagccacgcg aatgaagttt gattaaggga gataacaaaa
     7321 atggcaatgg tccaaccgaa atcgcaaaaa gctcgtttat ttattactca cctgctactg
     7381 ctacttttta tcgcagcgat tatgttcccg ctgctgatgg tcgtcgctat ctcgctgcgt
     7441 cagggaaact ttgcgaccgg cagcctgatc ccggagcaaa tctcctggga tcactggaaa
     7501 ctggcgttag gttttagcgt tgaacaggct gatggtcgca ttacgccacc gccattcccg
     7561 gtactgctgt ggctgtggaa ctcggtaaag gtcgccggga tttccgcgat tggcattgtg
     7621 gcgctctcca ccacctgcgc ctacgctttc gcccgtatgc gctttccagg caaagcgacg
     7681 ctgctgaaag gaatgctgat tttccagatg ttcccggcag tactttcact ggtcgcgttg
     7741 tatgcgttgt ttgatcgtct gggtgagtac attccattca ttggcctgaa tactcacggc
     7801 ggcgtaattt tcgcgtatct gggtgggatt gcgctgcatg tctggaccat caaaggctat
     7861 ttcgaaacca tcgacagttc gctggaagaa gctgctgcgc tggatggtgc gacaccgtgg
     7921 caggccttcc gccttgtcct gttgccgctg tcagtaccga ttctggcggt ggtattcatc
     7981 ctgtcgttta tcgctgccat tactgaagtt ccggtcgcgt cgctgttact gcgtgacgta
     8041 aacagctaca ccctggccgt ggggatgcag caatacctca acccgcaaaa ctacctgtgg
     8101 ggtgactttg ccgccgctgc cgtgatgtct gcattaccga tcaccatcgt cttcttgctg
     8161 gctcaacgct ggctggtcaa cggcctgacg gcaggtggtg tgaaaggtta aagatgttgt
     8221 tctgccaatg ttatgccgct gcaccctcaa cttacgttat cccaacttgt gactgttatt
     8281 cggcgctcca cggagcgcct ttttttcttt cgtctgcaat ctgaatcgtt cgccggttaa
     8341 tatttccatc atagagctta ttatttttac gttatttgtt ttcccactta cgataattct
     8401 ctttcgtgct ctgagtcacg gcaatagtat tgtttttatc aattttggat aattatcaca
     8461 attaagatca cagaaaagac attacgtaaa cgcattgtaa aaaatgataa ttgccttaac
     8521 tgcctgacaa ttccaacatc aatgcactga taaaagatca gaatggtcta aggcaggtct
     8581 gaatgaatac ccagtataat tccagttata tattttcgat taccttagtc gctacattag
     8641 gtggtttatt atttggctac gacaccgccg ttatttccgg tactgttgag tcactcaata
     8701 ccgtctttgt tgctccacaa aacttaagtg aatccgctgc caactccctg ttagggtttt
     8761 gcgtggccag cgctctgatt ggttgcatca tcggcggtgc cctcggtggt tattgcagta
     8821 accgcttcgg tcgtcgtgat tcacttaaga ttgctgctgt cctgtttttt atttctggtg
     8881 taggttctgc ctggccagaa cttggtttta cctctataaa cccggacaac actgtgcctg
     8941 tttatctggc aggttatgtc ccggaatttg ttatttatcg cattattggc ggtattggcg
     9001 ttggtttagc ctcaatgctc tcgccaatgt atattgcgga actggctcca gctcatattc
     9061 gcgggaaact ggtctctttt aaccagtttg cgattatttt cgggcaactt ttagtttact
     9121 gcgtaaacta ttttattgcc cgttccggtg atgccagctg gctgaatact gacggctggc
     9181 gttatatgtt tgcctcggaa tgtatccctg cactgctgtt cttaatgctg ctgtataccg
     9241 tgccagaaag tcctcgctgg ctgatgtcgc gcggcaagca agaacaggcg gaaggtatcc
     9301 tgcgcaaaat tatgggcaac acgcttgcaa ctcaggcagt acaggaaatt aaacactccc
     9361 tggatcatgg ccgcaaaacc ggtggtcgtc tgctgatgtt tggcgtgggc gtgattgtaa
     9421 tcggcgtaat gctctccatc ttccagcaat ttgtcggcat caatgtggtg ctgtactacg
     9481 cgccggaagt gttcaaaacg ctgggggcca gcacggatat cgcgctgttg cagaccatta
     9541 ttgtcggagt tatcaacctc accttcaccg ttctggcaat tatgacggtg gataaatttg
     9601 gtcgtaagcc actgcaaatt atcggcgcac tcggaatggc aatcggtatg tttagcctcg
     9661 gtaccgcgtt ttacactcag gcaccgggta ttgtggcgct actgtcgatg ctgttctatg
     9721 ttgccgcctt tgccatgtcc tggggtccgg tatgctgggt actgctgtcg gaaatcttcc
     9781 cgaatgctat tcgtggtaaa gcgctggcaa tcgcggtggc ggcccagtgg ctggcgaact
     9841 acttcgtctc ctggaccttc ccgatgatgg acaaaaactc ctggctggtg gcccatttcc
     9901 acaacggttt ctcctactgg atttacggtt gtatgggcgt tctggcagca ctgtttatgt
     9961 ggaaatttgt cccggaaacc aaaggtaaaa cccttgagga gctggaagcg ctctgggaac
    10021 cggaaacgaa gaaaacacaa caaactgcta cgctgtaatc ttcctgtcca gcacgccgcg
    10081 ccatttcggc gtgctgactt tttactcccg cttcagccgt ttcgaattac acagccacag
    10141 ggtgatcacc agtaacagga tcgcagccga gtagatcaac acatccagtg gcgatttatg
    10201 atcgacgatg atcaagcgca caatggcggt gatcccaata tagacaaagt aacgtagcgg
    10261 gaagtgaaaa ccggactgaa agtacttcac aatcagcgcg ataaattcga aatagagaaa
    10321 gtaaaccacc agtccttcta ccagctcata tttgctggtt tgttctggcg cgaacagcac
    10381 atcagccaga tgcaccgttt ctttgccgag gaagacaacc aaaatcaggc cgaggcacag
    10441 caggccaaga ttgagtacgg tctgcaaaat ggtggagata aactccacgc gcggacgaga
    10501 gagtgacgtc atagcagtac ctccttcaca gtggcgagct tcctgtataa cgcaaaaatg
    10561 tgacggagat ctatattttt tgtgtatgtt ttgttcaacc tggatttgga gcgcgcctcc
    10621 accaaagccg gatataccta cccgtaggcc ggataagccg cgcctggcgg cgcatccggc
    10681 aagacaaacc gcaccaaagc cggtaattca aaaatcaccc attcaggtga ttcccagcca
    10741 ccagcaatgc gcgaaaaatc gacaatgttc ctctggaaca aatgaaacgt aacctgataa
    10801 aggtggtaaa aatgaagcct tattttgctg ctttgatgtt atcagtctct gttcttcctg
    10861 cttatgctgg tccgctcggt actgctgata aagccgacct accgcaaagc aatgtctcca
    10921 gcccaatgat ggcccagtcg ctcaggcaac cagacctgca accgatatcg acggacagga
    10981 agacagaatg ttttcgcctt tacacaccag atcgcaaacc gggagtgaac tgcgttcctg
    11041 atggctcgac aggccattaa gaatgaaggt gccagtgagt gcgaaaactg gcacctttcc
    11101 catgacttag cggaaattga cgctacggtc gctggtcatg tcatacaact ggaacttacg
    11161 cccaagttgc tgaccaccgt cacgcgtcag cggcgtccag ccaatcgccg cacggctgcg
    11221 tgtcgggcca gacgagaaga gatccaacgg taccgagaca tacacgcctt tggtgaagtc
    11281 cccttcgccg tactcctctt tcgaaacatt agtgatcgtg gcatagccac ccaccaccac
    11341 gccgctatca aagcgtttgg cgatctccag cgtgccgcct ttatcccctg ccagatactg
    11401 cccgacgctg gctttaacta acacatcctg agcgaaagat ggcgtccagt aggcggtcag
    11461 atgtccggtt ttcacgctgt agtcggtgaa tttcatcata tcttttgcac tacgccagtc
    11521 gcgctgttta acgtagttgg catccagacc aaacgcccag ttgctgtcca gcgggcgata
    11581 caacacttct gcccccgcac cgccaaacat ggtttcgaga taaccaccgt agacctgacc
    11641 gtagaagccg ttgcccagat gctggaagta gttggcttgc aggttattca catagacatc
    11701 gttctgcaca tactcgcgca catgggtacg cacgcgcggt aagtgcgagt cctgcggagg
    11761 attagtgtag ttaaacttgt cgtagttgtt ggcaagattt gcaaacaggc tgccggtggt
    11821 cagcagatgg tccgtcagcc acaaatctgc cgttcccatc acgcccagct gatacatgta
    11881 aaagttttcc gggccaccga ccgactggtt cagcaccgga tcgatatgga aatcaaagcg
    11941 tgatttgtcg atataccagc cctgctcggt ggactgcgga accactggct cgacgcgttt
    12001 ttgcgccagc gtcgtttcgt ggcccaacgg ctctccggcg agatgatttt tcaggctggc
    12061 gacatcggtt tccgtcgtca cctgcggcat gttaaggcga ttttccgtaa tgcggatcgt
    12121 tttgatccca tccggcagat cgttcatcac gatccgattc gcacggatga tcccttcgcg
    12181 cgaatcacga tatttcacct gctcgccggt aacatacagc gtatcgcctt tcgcctggat
    12241 ctgtggatcg gcaagtccgg cattgtattt caacagcgtt aactgattcg ccaccaccga
    12301 atgctgcaaa atggcatcct gcggctgcgg ttgatattgc gggcgggcgt tatcgttgta
    12361 agacgggcgc agatcgttaa agttggtgcg caacgtaacg ccaaacataa aggtgttgcc
    12421 acgttcatag ctaaggttaa cgtcggccca atcggtaacg cgataaatcg caccgacgtt
    12481 aaacttactt ttttgctcca gcttcccggc aaaatcctgc tgataattat tgccttcata
    12541 ctccagtttc aggcgcagcg gttgccaggg cgtctggtat tccacgccgc caaacagtga
    12601 ggcaggaccg tggaacatct ggctaccgtc gatagatccc gcctgtttgt agctgttatc
    12661 gcgatagcaa tatttatcac tggctgaaca gagcggattt ttcacattac cgctggtgcc
    12721 caaatatccc cagcccaggc cgagcgtaaa atcgaacggc ccccaggctt tgctggcaac
    12781 aagatattcc gcatcaaaca gccccgtacc gccgatatcc cgcgcaccaa ccgccacttg
    12841 cggcagccag taactctctt cccacaaacg cagtttgaga tcgaaggctt tatctttata
    12901 cgtttgatcg ccagagaacg cttcgacgct gctgtactgc cgggtgcgca cgtcggtgta
    12961 gcgcagcgtt gtttccagcc acgggaagag ttgcactgaa gctgagtaat aacggtactg
    13021 atcgttatcg cgatagttca gactcaactc cccttcccgt gccatacgcg cggtgggcgt
    13081 ttgtaataat cctacgccac cgaaatccga ctgcgacgga ccaatgggcg caggatatgt
    13141 ttcgccgtag caagctgtgc taatgcccag cgccagtaag ctaagcagat gtcttttttt
    13201 cattattgag gtatccgctg cgtcagagtc tgaagaatgt cggcgttaag ggcatcaggc
    13261 gtctcactcc agacggagtc cgcgaggcca acataaataa tgctgccggg catcggctct
    13321 acgtgacgct tgttccagta agccaccggc gctttttgcg tgcgtccgtc cgggtaaacc
    13381 acccacgcgt agctgcgatc cgcaccgctg agcaggctct ggtcagagag atagctcgcc
    13441 acgtcgcgac ctggagtgaa tggctgcttg ccaggacggc tgataagccc gaacaacgtg
    13501 accgtggacg gcggtggtcc gacccacagc gtgtagttgc cctgcaacgg cgggttaccg
    13561 cgttcggcaa cgcggacgat atcgggatca agattgattt tttgcctgcc cgtcactttc
    13621 aacgcctgaa tttgctggcg taaggcgtta atcgcagcgg catcgtcggc gctggaatct
    13681 gcgccctgtt ctgccagccg tgtcagcaac gcctgctgct gacgcaatgc tgccgccgtt
    13741 gccagctctt cgctaatcac cgcaccgggc caccagctgt ttgccagccg cggttggcct
    13801 accagatcga ttaaatgctc tgcgcccgtt agcgttttgg cctcactgct gccattgctg
    13861 aacaccttga cggttcctgc cgcgaagacc gatgacgctc ccacactcaa aagcaacgcg
    13921 acaatagttt gtttaatcat tgttttgccg ccttgatgag agtggttttc accggaaaat
    13981 aatccgcgcc gagatactgt tccgactggc gaatttgccc ttcgctgtcg atccaatagc
    14041 ggttatgcca gcgcgcctgg tcggtggaga cttcttcgtc cagcacgcga accggggttt
    14101 catcgctgcc gactttgacg gtatcggtgc catcccattt gaagactgag cgtgcggtgg
    14161 cgtagcgtac ctgctggtac tcggtccagc ccatcgtgcg cgtccagctt gcgccatcaa
    14221 cgatttgtgc gggtttaatc agcgggtcgg cagcaaggtt attcacttca atcaggttgt
    14281 cgccgccgag cagagtcttc accagacggc catgttgggt aacgagagta gcctgatcct
    14341 gagtgaccca tttttgttgt ccgtcttcag cgaaggccag caccacaaat aactgcggcc
    14401 cgccattaag ctgcatgtac tggctggcgt agggcatatt ttgaatatca tcatccgtca
    14461 gctgtacgcc tggcgtgccg aacagactgt cccacagtga attgcccagc tctttagtcg
    14521 tggctgaaca ggcctgtaat aacaggcaga taagaatgag tgcaggtcgc ttcacgactc
    14581 ttctccagag gggcagaata accacaccgg agtgtggtta tggttaatcc cttcatactt
    14641 ctagccacag atgcaatgac tcgaattatt ttggggatac atactttatt actgggtact
    14701 ggtggtcgtg gttgtggtgg tcccggtatt agaaccatca ccgccaccgg ttgccgcaag
    14761 cgcgacaccc accgccgagc ttacggtgct gacgctggtc gcggaggaac tccccgccga
    14821 aaccgacgtt gctgccgacc ctgccgcttc gcccacctgt acaggtgcag cccacgcaga
    14881 agtcgccgca agcgcagata tggcaaaaat gccatacaga acttttttca taacaatttc
    14941 ccttcattga atgaatggag atttacccaa aaacatttcg ggcgggatcg agtatacaca
    15001 actaaagcat gcgaattacg gcgcggggaa ttagcgatgg cgttttagga taattggaat
    15061 gaatatcaaa tataagtttc aacttatatt taaataacaa taaaaatcat aaacttaaaa
    15121 taaaaacaaa agcaattaat ctgcgtattt tccgaaataa acaacgatta aaaatctatt
    15181 ttaggattaa cctcacggta tgatttccgt taaattacag acaaggggat ttatctgata
    15241 aaaaaatgcc gacataacgt cggcattgtt attaaggtta tttaatcaat cgtgctatgt
    15301 attaattgcc gaatacgatg tacatatcgg catcgacctg taggcctgat aagacgcgac
    15361 cgcgtcgcat caggcatcgg ttgccggatg cggcgtgaac gccttatccg gcctacatat
    15421 cgacgatgat taaccgcgcc acgctttata gcggttaatc agaccattgg tcgagctatc
    15481 gtggctgctg atttctttat catctttcag ctctggcaga atacggttcg ccagctgttt
    15541 acccagttcc acgccccact ggtcgaaggt gaagatgttc aggatcacgc cctgagtaaa
    15601 gattttgtgc tcatacagcg caatcaacgc acccaggctg aacggagtga tttcacgcag
    15661 caggatggag ttggtcgggc ggttaccttc gaatactttg aacggcacca cgtagtcaag
    15721 cgttgccgga tctttaccct gatcacgata ttcctgctca accacttcgc gggatttacc
    15781 aaacgccagc gcttcggtct gggcgaagaa gttagacagc agtttctggt gatgatcaga
    15841 gagcgggtta tgggtgatag ccggagcgat gaaatcgcac ggtaccattt tggttccctg
    15901 gtggatcagc tggtagaacg cgtgctgacc gttagtgcct ggttcacccc agataatcgg
    15961 gccagtctgg taatccacaa cgttaccgtt acggtcaaca tacttaccgt tggactccat
    16021 attgccctgc tggaagtacg ccgcgaaacg gtgcatatac tggtcatacg gcagaatcgc
    16081 ttcagtttcc gcaccaaaga aattgttgta ccagatgcca atcagcgcca gcagtacagg
    16141 caggtttttc tcggcaggcg tggtggagaa atgcttgtcc atcgcgtgtg cgccggaaag
    16201 cagttcaacg aagttatcaa agccgatgga gagaacaatc gacaggccaa tcgctgacca
    16261 caaagagtaa cggccgccaa cccagtccca gaactcgaac atgttggcag tatcaatacc
    16321 aaactcgcca acggctttgg cattggtgga aagcgccgca aagtgttttg caacgtgttt
    16381 ttcatcacct gccgctttca ggaaccagtc acgcgcgcta tgggcgttgg tcatagtttc
    16441 ctgagtggtg aaggttttag atgctaccaa gaacagcgtg gtttccgggt ttactttttt
    16501 cagcacttcc gcgatgtgag tcccatcgac gttagaaaca aagtgcatgt tcaggtggtt
    16561 tttgtacgga cgcagagctt cggtcaccat gtatgggccg aggtcagaac cgccgatccc
    16621 gatgttcact acgtcagtga ttgctttgcc ggtataacct ttccactcac cggaaataat
    16681 cgcttctgag aaggttttca tcttctccag caccgcgttg acttccggca ttacgtcttt
    16741 gccatcaacc aaaatcgggg tattgctacg gttacgcagc gctacgtgca gcacggcgcg
    16801 gttttcagtg cggttgatct tctcgccaga gaacatcgac ttaatcgcgc ccgccagatc
    16861 gcactctttc gccagatcct gtaatttcgc cagcgtctct tcagtgatgc ggtttttgga
    16921 gtaatccacc agcatctgat cgtcgaaggt tgcggagaac ttagaaaaac gatcgccgtc
    16981 tttagcaaaa agatcggcga tcgtaacgtc tttcatttca tcgaagtgtt tctgtagtgc
    17041 ctgccaggca gcggtctgcg ttggattgat gtttttcatt agcaatactc ttctgatttt
    17101 gagaattgtg actttggaag attgtagcgc cagtcacaga aaaatgtgat ggttttagtg
    17161 ccgttagcgt aatgttgagt gtaaaccctt agcacagtga agcatttatt agctgaacta
    17221 ctgaccgcca ggagtggatg aaaaatccgc atgaccccat cgttgacaac cgccccgctc
    17281 accctttatt tataaatgta ctacctgcgc tagcgcaggc cagaagaggc gcgttgccca
    17341 agtaacggtg ttggaggagc cagtcctgtg ataacacctg agggggtgca tcgccgaggt
    17401 gattgaacgg ctggccacgt tcatcatcgg ctacaggggc tgaatcccct gggttgtcac
    17461 cagaagcgtt cgcagtcggg cgtttcgcaa gtggtggagc acttctgggt gaaaatagta
    17521 gcgaagtatc gctctgcgcc cacccgtctt ccgctcttcc cttgtgccaa ggctgaaaat
    17581 ggatcccctg acacgaggta gttatgtctg aaattgttgt ctccaaattt ggcggtacca
    17641 gcgtagctga ttttgacgcc atgaaccgca gcgctgatat tgtgctttct gatgccaacg
    17701 tgcgtttagt tgtcctctcg gcttctgctg gtatcactaa tctgctggtc gctttagctg
    17761 aaggactgga acctggcgag cgattcgaaa aactcgacgc tatccgcaac atccagtttg
    17821 ccattctgga acgtctgcgt tacccgaacg ttatccgtga agagattgaa cgtctgctgg
    17881 agaacattac tgttctggca gaagcggcgg cgctggcaac gtctccggcg ctgacagatg
    17941 agctggtcag ccacggcgag ctgatgtcga ccctgctgtt tgttgagatc ctgcgcgaac
    18001 gcgatgttca ggcacagtgg tttgatgtac gtaaagtgat gcgtaccaac gaccgatttg
    18061 gtcgtgcaga gccagatata gccgcgctgg cggaactggc cgcgctgcag ctgctcccac
    18121 gtctcaatga aggcttagtg atcacccagg gatttatcgg tagcgaaaat aaaggtcgta
    18181 caacgacgct tggccgtgga ggcagcgatt atacggcagc cttgctggcg gaggctttac
    18241 acgcatctcg tgttgatatc tggaccgacg tcccgggcat ctacaccacc gatccacgcg
    18301 tagtttccgc agcaaaacgc attgatgaaa tcgcgtttgc cgaagcggca gagatggcaa
    18361 cttttggtgc aaaagtactg catccggcaa cgttgctacc cgcagtacgc agcgatatcc
    18421 cggtctttgt cggctccagc aaagacccac gcgcaggtgg tacgctggtg tgcaataaaa
    18481 ctgaaaatcc gccgctgttc cgcgctctgg cgcttcgtcg caatcagact ctgctcactt
    18541 tgcacagcct gaatatgctg cattctcgcg gtttcctcgc ggaagttttc ggcatcctcg
    18601 cgcggcataa tatttcggta gacttaatca ccacgtcaga agtgagcgtg gcattaaccc
    18661 ttgataccac cggttcaacc tccactggcg atacgttgct gacgcaatct ctgctgatgg
    18721 agctttccgc actgtgtcgg gtggaggtgg aagaaggtct ggcgctggtc gcgttgattg
    18781 gcaatgacct gtcaaaagcc tgcggcgttg gcaaagaggt attcggcgta ctggaaccgt
    18841 tcaacattcg catgatttgt tatggcgcat ccagccataa cctgtgcttc ctggtgcccg
    18901 gcgaagatgc cgagcaggtg gtgcaaaaac tgcatagtaa tttgtttgag taaatactgt
    18961 atggcctgga agctatattt cgggccgtat tgattttctt gtcactatgc tcatcaataa
    19021 acgagcctgt actctgttaa ccagcgtctt tatcggagaa taattgcctt taattttttt
    19081 atctgcatct ctaattaatt atcgaaagag ataaatagtt aagagaaggc aaaatgaata
    19141 ttatcagttc tgctcgcaaa cgaattcccg tacactgaac tctctggctc actgagggca
    19201 ccatcatggc actcccccgt attacccaaa aagagatgac tgaacgcgag cagcgtgaac
    19261 ttaaaacact gctggatcgg gcgcggattg cgcatggtcg cgtattgacc aactccgaaa
    19321 ccaacagcat taagaaagat tacatcgata aattaatggt tgagcgtgag gctgaagcga
    19381 aaaaagcccg ccagttgaag aaaaagcagg cttataaacc ggatcctgaa gcgtcattta
    19441 gctggtcagc aaatacgtcg acgcgcggca ggcgctaatc cacaatcaac gcctgagatt
    19501 ttcactcgtc agtgtgaaca caattttccc ctcaccctaa cccttttccc gaaggggcga
    19561 ggggactgtc cgggcacttt tgggccgttt tcatcagtct gaggcgttaa tcagcgcccc
    19621 ttctttttac gccccggcga ggtaaaacgc ttaccgttgg acgccgggcg accgcctttt
    19681 tccgccgttt tttccatctt aacgactgga cgtttgatgc ccgctgtttt cggtttggcc
    19741 ttcgctttag gttttacctc ggaagaggaa ttttcaatga gcttaaagag gtcgattaac
    19801 tcatcgtcgg ttaaatcgcg ccattccccc agcggaatgc cgcttaagct aacgttcatg
    19861 atgcgcgtgc gttccagctt tttcacttca tagccgaaat gctcgcacat gcgccggatc
    19921 tgacggttca gcccctgcac cagggtaatg cggaagacaa acggcgcttc ttttttaact
    19981 ttgcactttt tggtcactgt cccgaggatt ggcacccccg cactcatgcc gcgaataaac
    20041 tcctcggtaa tcggtttatc gaccgtcacc agatactctt tctcatgatc attgccagca
    20101 cgcaggatct tattcaccag atcgccgtga ttggtgagga aaatcagccc ctgggagtct
    20161 ttatccaggc ggccaatcgg gaacacgcgt ttgctgtggt taacgaaatc gacaatgtta
    20221 tcgcgctcgc catcttcggt ggtgcttaca ataccaacgg gcttgttcag ggcgataagt
    20281 accaaatctt cggcttcccg aggttcaatc aactgaccgt ttactttcac aacgtcgccg
    20341 ggtttcacct gatcgccaat ggtggctcgc ttgccattaa ggaacacatt gccttgctcg
    20401 atatagcgat ccgcttcgcg gcgtgagcaa attccgcttt cgctgatgta tttatttaaa
    20461 cggactgatg agtcgggcag cataaattct cctgtaaaaa acggaatata ccgtaccttt
    20521 gggttgataa aaaatagtca tgagcgaact atttgttatt tccattggct tgaattcgtt
    20581 acctgctcaa atcactttcc agaagcaatg tgcgacatcg tgagccatgt cagtaagtgg
    20641 ttaaattcgc agtggtagca tgcctcccgt gatttcttac taaccggaga agtaatggaa
    20701 ctgcttttat tgagtaactc gacgctgccg ggtaaagcct ggctggaaca tgcactgccg
    20761 ctaattgctg aacagttgca gggtcgccgc tcagcggtgt ttatcccttt cgctggcgta
    20821 acgcagacct gggatgatta cacagcgaaa acggctgcgg ttctcgctcc gctgggtgtt
    20881 tctgtcaccg gtattcatag cgttgtcgat cccgttgccg cgattgaaaa tgctgagatc
    20941 gtgattgtcg gcggcgggaa tactttccag ttgctgaaac agtgccgcga gcgcgggctg
    21001 ctggcaccaa ttactgacgt ggttaaacgt ggcgctctgt atattggctg gagcgcaggc
    21061 gctaaccttg cttgcccaac tattcgtacc accaacgata tgccgattgt cgatccgcaa
    21121 ggtttcgatg cgctaaatct gttcccgctg caaatcaacc cgcacttcac caacgcgctg
    21181 ccggaaggcc ataaaggtga aacccgtgag cagcgtattc gcgaactgct ggtcgtcgcg
    21241 ccagaactga cgattattgg tctaccggaa ggtaactgga tcacagtgag taaaggtcac
    21301 gctacgctgg gtggcccgaa caccacttat gtgtttaagg ctggtgaaga agcggttccg
    21361 ctggaagctg gtcaccgttt ttaagtgaat tgccggatgc atgatccggc atcttgttca
    21421 tagtgcctga tgcgacgctt gacgcgtctt atcaggccta caggattcac aatattaata
    21481 ctcgtcccgt ccttcatctt catccggctg ttccagcaca ctgtaagcca ccgaacaaaa
    21541 cagcgagttc aggcgctgca tatctcccag taagcctaaa tgtagcgaac tggtttcaat
    21601 gctctgcacg ttttgctgat gcaggcgatc gacgtgggcg tgggaatagc ggcgattaag
    21661 aatgcgaaaa cgatgtttgc tgcgacgcaa acgacgagcg ctggtgacat cgccagagaa
    21721 gaacaccgac attgccagct ttaaattact gagcaattgc tcatagagcg catccagttc
    21781 cttcaaccca tcaagcgaaa atgcccgccg tgctgccagt gatttgtcag caatttcgct
    21841 gcccatgcgc tcgacgatat cggaggcctg ttcaaggttg agcgacattt cgatgatctc
    21901 tgcccagcgg cgcgactctt cctccgccag ctcttctttt ggcatccgcg ccagatacag
    21961 cttaatggcg gtgtagagaa cgttgatatc atctgccagc ttacgcagct ctttctcctg
    22021 ccgtggctca ccgtgcatca ctttattcaa cccttccatc atctgttcca tggcgtcgcc
    22081 aatgcgcagg gtttcgcgcg cggcgttcgc cagagcaagc gtgggcgtat ccagcgcgct
    22141 gacatccaga tgtttaggcc gtagctgggt atccagttcc ggttcatcgc gaataatcgt
    22201 tttgcaaaac cgtgccatcg ggtcaacaaa tggcagcatg accaggcaac gtacaaggtt
    22261 gtagaagacg tggaaataga tcaccagttc cgcttttggc aatgacaact tccccattgt
    22321 ctctgccagc aaatggacaa acggcaggat aatcaggcta cccaccagct taaacagcag
    22381 actacccagc gcgacacggc gggctgcggc attggcggca ctgttgttga gcattgccag
    22441 cagaccggaa ccgaggttag caccaatcac cagacagagc gccacgggga aggagataat
    22501 gcctgcggcg gtcagagtcg cggtcagcag tacagcagca aggctggagt agctgataat
    22561 ggcgaacatc gcgccaatca gcgcatccag cagaatatcg ccggtcagcg aggcaaagat
    22621 cacctgaacg ccgtttgcct gggtgatcgg cgttacggcc tgcacaatca actccagcgc
    22681 tagcaaaatc agcccaagac caataccgac gcggcccagt tgcccggcgc gtgactgttt
    22741 gcgtccgagg aaaaaaatca cgccgataaa aataagtaac ggtgacagcc aggataagtc
    22801 gaaggtgaga atacgcgcca ttagcgccgt cccgacatct gcacccagca caatgaccag
    22861 agccggtgcg agggctacca gatcctgagc gacaaacgag gtcaccagca tggtggtggc
    22921 attactgctc tgtaccagtg cggtaacgcc gatccccgcg caaaaggcga gcggcttttt
    22981 ttcgacgctc cggctaagga cagtacgcaa acgcgcgccg aagacgcgca ttacgccggt
    23041 tcgaacaata tgagtccccc agaccagcag ggcgacggca gaaagcaggt gaagcagcgt
    23101 taacacgagt tcaggttctc cttatcgtta tatgttcctg aagcaattga atgaccaaag
    23161 gaccggaaac acgctgactg gcatctttac tgtgcctttt gacattcgtt tttccggcta
    23221 agattattcc agcctgtttc cagtataagt gtttcatatt aataaagaga cagggcactc
    23281 attgagcgcc ctgtttgttg taaggaaaag tgacagattt gtgaatcagt ccgcgtcata
    23341 ccccagattc ggtgccagcc agcgctcaac ttcggtaacg ctcatacctt tacggcgggc
    23401 ataatcttca acctgatcgc gctgaatttg tgctacagcg tagtacttgc tgtccgggtg
    23461 gctgaagtac caacccgaaa ccgatgcacc gggccacatg gcgaaagatt ctgtgagttt
    23521 catgccagtg tgtttttcca cttccagcag ctcccagatg gtggcttttt ccgtatgttc
    23581 cgggcaggcc ggatagcccg gtgccggacg gatgccctgg tagttttcgc ggatcagctc
    23641 ttcgttgctg aggttctcgt tcggcgcata gccccagtag actttacgca cacgctcatg
    23701 gagatactcc gcaaaggctt cggctaaacg gtcggcaagc gctttcacca tgattttgtt
    23761 gtaatcatcg tgctgcgctt caaaggcatc agccagtgcg tcctcttcca gcccgccagt
    23821 cacggcaaat gcgccgatgt aatctgcttt accagaaagc ttcggcgcaa cgaagtcagc
    23881 gagacagtag ttagcgaagc ctgttttttc ggtctgttga cgcagatggt ggctgacgtt
    23941 gatcacatgg gtacgcgttt cgtcacggta gatttcaatg tcatcgccca cacggtttgc
    24001 cgggaacagg cccaccacgc cacgcggatt cagcgttttc tcggcgctta atttatccag
    24061 catgtcgttg gcgtctttaa acagccgctg cgcctcaacg cccaccactt catcttccag
    24121 aatgcgcgga tacttcccgg ccagcgacca ggtcataaag aacggtgtcc agtcgatgta
    24181 attacgcagc gtttcgatgc tggcttcgac ttcctgcacg ccgagacggt gcgccaccgg
    24241 cggcgtgtaa gcctgccagt caaaagcgaa atcgttatcg cgcgccgctt ccagcgtgac
    24301 cggtggtgtg cgcggtttct tgcgcccgtg ctgaatacgt acggtttcgt actccttgcg
    24361 ggtacgagcg acaaaatcat cacgctgggt atcggaaagc agcgccgcca ccacaccaac
    24421 ggtacgcgag gcattctgca catacaccgt cgggccgctg tagttctgct cgattttcac
    24481 cgccgtgtgc gcttttgagg tcgtcgcgcc gccaatcagt aacggaatag tgaagccctg
    24541 acgctccatc tctttcgcca cgttaaccat ctcgtccagc gacggcgtga taagccccga
    24601 aaggccaatc agatcagcat tcacttcttt agcggtacgg agaatttttt ccgcaggcac
    24661 cataacgccg agatcgacaa tttcgtagtt gttacattgc agcaccacac caacgatatt
    24721 tttaccgatg tcgtggacgt cgcccttcac ggtggcgatc accatcttgc cgttggtttt
    24781 gccctgctct ttgctggctt caataaacgg ttcgaggtag gccaccgcct gtttcatgac
    24841 gcgcgccgat ttgaccacct gtggcaggaa cattttccct tcgccaaaca ggtcgccgac
    24901 cacattcatg ccgtccatca acgggccttc aatcacttca atcgggcgcg tagcctgctg
    24961 gcgggcttct tcggtatcct gctcgataaa ctcggtaatg cctttgacca gcgagtattc
    25021 cagacgttta ttcacttccc acgagcgcca ctccgcctgc tgggcgttgg cggtgtcgtc
    25081 ggttttgctg ccgcgatatt tctcggcaag ctccagtaaa cgctcggtgc catcgtcgcg
    25141 acgattaaga atcacatctt ccaccgcgtc gcgcagttca gcgggtaggt cgtcgtaaat
    25201 cgccagttgc ccggcgttga cgatccccat atccatgcca ttgcgaatag cgtagtagag
    25261 gaacactgcg tgaatggctt cgcgcaccgg atcgttgcca cggaacgaga aagaaacgtt
    25321 agatacgccg ccggaaatca gcgcgtgcgg cagttcgcgt ttgatgtctt cacacgcgcc
    25381 gataaagtcc tgcgcgtagt tgttgtgctc ttcaatgcca gttgcgaccg cgaagatgtt
    25441 tgggtcgaag atgatatctt ctggcgggaa gccaacctct tcggtgagga ttttgtacgc
    25501 ccgacggcaa atctcgattt tccgtgcgcg agtatcggcc tgtccctgtt cgtcaaaggc
    25561 cattaccacc actgccgcac cgtagcgacg caacaatttc gcgtgatgga taaaggcatc
    25621 gacgccctct ttcatcgaga tagagttaac aatgcctttg ccctggatac acttcagacc
    25681 tttttcaatg acgtcccatt ttgaggagtc gatcataatc ggcacgcgag cgatatccgg
    25741 ttcaccggca atcagattga gaaaacgcac catcgccgct tcggcatcga gcatcccttc
    25801 atccatgttg atatcgataa tctgcgcgcc gttttccacc tgttgacgcg cgacatccag
    25861 cgcctcgctg tatttctctt ctttgatcag gcgcttgaac ttagcggaac cggtgacgtt
    25921 ggtgcgttca cccacgttca caaacaggct atcttcgcca atgttcagcg gctccaggcc
    25981 ggacaaacgg caggctacgg gaatttccgg cagtttgcgc ggcgctaatc cttctactgc
    26041 acgactcatc gctgcaatat gttgtggcgt ggtgccacag cagccgccga cgatattgag
    26101 aaaacccgct tgcgcccatt cacgtatctg ttttgccatc gtgtcggcgt cgagatcgta
    26161 ctcaccaaag gcgttgggta gcccggcgtt cgggtgcgcg gtgacgtagc attccgcaat
    26221 ccgtgacagc tcctgcacgt actggcgcag ttcatcgggc cccagcgcac agttcaggcc
    26281 aaaggtcaga gcttcggcgt ggcgcaatga gttgtaaaat gcttcggtgg tctgcccgga
    26341 gagcgtgcgc ccggaggcgt cggtgatggt gccggagatc ataatcggca gctcaacgcc
    26401 cagcgcttca aactccgttt tcaccgcaaa taccgccgct ttggcgttaa gggtgtcgaa
    26461 aacggtttca atcaggatca gatccgcgcc accttccacc agcgctttgg tggactctcg
    26521 ataagccgcc accagcccgt caaaagtgat attacgaaat gccggatcgt tgacgtccgg
    26581 agaaatagac gccgtgcggt tggtcgggcc gagaacaccg gcaacgtagc gcggtttctc
    26641 tggcgtgcgc gcggtccact cgtcagcaca agctcgcgcc agtttcgccg ccgcaaagtt
    26701 gatttccgcc gacagggatt ccatctggta atccgccatc gcaatggtcg tggagttgaa
    26761 ggtgttggtt tcgatgatat ccgcgcccgc ttcaaagtag gcgttgtgga tagcggcgat
    26821 cacttccggt ttactgagta ccagcaggtc gttgttgcct ttgaggtcgc atggccagtc
    26881 ggcaaagcgt tcaccacgaa aatcggcttc gttcagtcga taactctgga tcatggtgcc
    26941 cataccgccg tccagcacca gaatacgttc atttaactgc gcacgcagtt gttccacttt
    27001 gctgctcaca cttgctcccg acacgctcaa cccagattta ataaaaattc aacaaaccat
    27061 actggcataa acgcatctgt ggtaaaagcg accaccacgc aacatgagat ttgttcaaca
    27121 ttaactcatc ggatcagttc agtaactatt gcattagcta acaataaaaa tgaaaatgat
    27181 ttccacgata cagaaaaagg agactgtcat ggtcgcaccc attcccgcga aacgcggcag
    27241 aaaacccgcc gttgccaccg caccagcgac tggacaggtt cagtctttaa cgcgtggcct
    27301 gaaattactg gagtggattg ccgaatccaa tggcagtgtg gcactcacgg aactggcgca
    27361 acaagccggg ttacccaatt ccacgaccca ccgcctgcta accacgatgc aacagcaggg
    27421 tttcgtgcgt caggttggcg aactgggaca ttgggcaatc ggcgcacatg cctttatggt
    27481 cggcagcagc tttctccaga gccgtaattt gttagcgatt gttcacccta tcctgcgcaa
    27541 tctaatggaa gagtctggcg aaacggtcaa tatggcggtg cttgatcaaa gcgatcacga
    27601 agcgattatt atcgaccagg tacagtgtac gcatctgatg cgaatgtccg cgcctatcgg
    27661 cggtaaattg ccgatgcacg cttccggtgc gggtaaagcc tttttagccc aactgagcga
    27721 agaacaggtg acgaagctgc tgcaccgcaa agggttacat gcctataccc acgcaacgct
    27781 ggtgtctcct gtgcatttaa aagaagatct cgcccaaacg cgcaaacggg gttattcatt
    27841 tgacgatgag gaacatgcac tggggctacg ttgccttgca gcgtgtattt tcgatgagca
    27901 ccgtgaaccg tttgccgcaa tttctatttc cggaccgatt tcacgtatta ccgatgaccg
    27961 cgtgaccgag tttggcgcga tggtgattaa agcggcgaag gaagtgacgc tggcgtacgg
    28021 tggaatgcgc tgactttttc tggcgggcag aggcaatatt ctgcccatca tacctgagtg
    28081 gcaatagaat aagggtgtct gttaatcgca ttgacgccaa aataacttaa tgtcatacac
    28141 ttcacacact tttattaact cagcattatt tttaaacatc aaaccactta attattaaca
    28201 aaatcgcaag atctcattcc accgaaactt ttacggctgc attatgagat tgagcgattt
    28261 atgatatttc tttagttgta atcatattaa attttttcac tgttctgata gttaaaattc
    28321 aagacatcaa taaacaatga gatatttaaa tgattactcg tattcctcgt agttctttct
    28381 ctgcaaatat taataataca gcccagacaa atgaacacca aaccctgagt gaattgtttt
    28441 ataaagaact cgaggataaa ttttctggca aggagctggc gacgcctcta ttaaaaagct
    28501 tctcagagaa ctgtagacaa aatggtcgtc atatctttag caacaaggat tttgtcatta
    28561 aattttccac gtccgtctta caagctgata agaaagaaat tacgataatt aataaaaacg
    28621 aaaacacgac acttactcaa accattgccc caatatttga aaaataccta atggaaattt
    28681 tacctcaacg ctcagacact cttgataaac aagaattaaa cctaaaatca gatagaaaag
    28741 aaaaagaatt cccaagaatt aaacttaatg gtcaatgtta ttttccgggg cgaccccaaa
    28801 accgtatagt atgccgacac attgctgcac aatatattaa tgatatttat cagaatgttg
    28861 attacaaacc ccatcaagat gattactctt cagctgaaaa atttctcacg cacttcaaca
    28921 aaaaatgcaa aaaccagact ttggcgttgg tttccagccg tcctgagggg cgttgcgttg
    28981 ctgcctgcgg tgatttcggg ctagttatga aagcatattt tgacaagatg gaatcaaatg
    29041 gcatcagtgt tatggcagcc atattactgg tggataacca tgctttgacg gtccggctaa
    29101 gaataaagaa cacaactgaa ggatgtaccc attacgtggt ttcggtttat gatcctaatg
    29161 taactaacga taaaataaga attatgagcg aaagcaaaga gaatattaaa cactattctc
    29221 tgatggattt tatgaatgta gattatagcc tcctgaaatg gtcaaatgat catgttatta
    29281 atcaatctgt tgcaataatt ccagcacttc cgaaagaaca gctattgatg ttaaaaggat
    29341 ctgtggatga aataacccct ccattatcac ctgcaacgat gaatttgcta atggcaattg
    29401 gtcagaatca ccaacttacg caactgatga ttcaactcca gaaaatgcca gaactacata
    29461 gaacagaaat gttgactgcc tataatagta ttaacctgcc aggtttatat ttggctataa
    29521 attatggtaa tgcggatatc gttgagacta ttttcaattc attgtcagaa acaggatatg
    29581 aaggattact ctcgaaaaaa aatctcatgc atattctgga ggcaaaagat aaaaatggtt
    29641 tttctggatt atttttagcg atatcacgta aggataaaaa tgttgtaacc tcgattctga
    29701 acgccttacc taaactggcc gcaacacatc atttagataa cgaacaagtg tataaattcc
    29761 tgagtgccaa aaatagaacg tccagccatg ttttatacca tgttatggcg aatggtgatg
    29821 ccgacatgct gaaaattgtt ttgaacgcgt tacctttgtt aattcgcaca tgtcatttga
    29881 ctaaagaaca ggtactcgat ctcctgaagg caaaggattt ttatggttgc ccaggactat
    29941 atctggcgat gcaaaatgga catagcgata tcgtgaaagt tattcttgaa gcattgccca
    30001 gcctagccca ggaaattaac atttcagctt ccgatattgt agatcttctg accgctaaaa
    30061 gtcttgcgcg cgacacgggt ttgtttatgg ccatgcagcg cggacatatg aacgttatta
    30121 atactatttt taacgcatta cccactctgt ttaatacgtt taaattcgat aaaaaaaata
    30181 tgaagcccct cctcctggca aataattcta atgaatatcc cggtttgttt tcagcgatac
    30241 agcataaaca acaaaatgtt gtagagacgg tttatcttgc tttatctgac catgcacgcc
    30301 tgtttggatt taccgctgaa gatattatgg atttttggca acacaaagcc ccacaaaaat
    30361 actctgcctt tgagttggct tttgaatttg gtcaccgggt tattgctgaa ttaatcctta
    30421 atacattaaa taagatggct gaaagctttg gctttacgga taaccctcga tacattgcgg
    30481 agaaaaatta tatggaagct ttactcaaaa aagcatctcc ccataccgta cgctaaatct
    30541 ttgcctgcgc cgatacgcat aaacatcttc cacatgccct tcacgtatgc ggttttgtag
    30601 tgcgcgccag taatcagcgc ggaacaggtc ggcgtgcatc tcttcaaaca gcggaccaat
    30661 acgcgggtcg gcgcatagcc agtggcgaaa ctcttccggg aaaacatcgc ccggcgagac
    30721 gctgtaccac ggttcgctgg caagttcgtc ttccggatag cgcggcggcg ggatgtcgcg
    30781 gaaattcact tccgtcatgt agcaaatttc atcgtaatca taaaaaacca cacgcccgtg
    30841 acgggtgaca ccgaagtttt taaacagcat gtcgccaggg aaaatgttag cagcggcaag
    30901 ctggcgaata gcgttaccgt attcttcaat ggcgtcgcgc aactgctgac cttccacttg
    30961 ttccagccag atattgagcg gcaccatccg ccgctcaata taaagatggc gaatcacaat
    31021 ttgttcgccg agatcggtga ttttttccgc tgcttcctga agcagtaatt ccattaatgc
    31081 cggggaaata tgccgcttct ccagcacaaa gttttcaaac tcctgggtgt ccgccattcg
    31141 gcccacgcga tcgtgctctt tcaccagttg atagcaggca cgaacgtgag cggcagacat
    31201 ctctttctgc ggcgcgaacc tgtctttgat gactttgaat acccgatcaa agcccggcag
    31261 cgtaaacacc aacatcacca ttccacgaat acccggcgct tcaatgaact gctcattaca
    31321 gccctgtaga taaacgagat attcgcgata gctttcggtt ttggcgtgct tctggcagcc
    31381 gatagccata tacaattcag cggtggtttt acctggcaga atttcccgta gccactcgac
    31441 cagcgctgcg ggcagcggcg cataaaccat aaaataagaa cgcgcaaagc caaaaacaat
    31501 gctcgcttcg gcggtcgtcg tcaggcaggt atcaataaat aactcgccgt cgtccgtctg
    31561 gtggatcggc agcaaaaatg gcaatgtgcc ggaaggtgtg atcagtttgc ctaccagcca
    31621 ggcggcttta ttgcggtaaa acagttcgtt cgccacctgt aaatgacttt ccgcgaggtt
    31681 gtctgtcccc agcgtttccg tcagatggcg aataatgtaa tggatgtcac ggcttttatt
    31741 ctgccagcgc aggcgcagcg gtaggtcgct gataacgcgc atcagtagag attcccagcc
    31801 gtgatcgggg tgaaagtctt tcgccagcgg gcggggaatg gtacgaaagc ggcgctctgg
    31861 ctgagagcta aagataaaaa gccgctcggg agtaagcgag cggtggtcaa ataaccgaca
    31921 gtacacggag ttaaaaaagc tctccgcaat ctcgaagcgc gggtaatccg gcaacagccg
    31981 ggtgtaatgc tctttaacac gtagtaaaaa tgccgcgtcc gtactttggc cgttagtaat
    32041 gcagcgcagt tgctccacga ccagaccaac gtgatgatcg taaagatgga tacggttttt
    32101 catcgcctgc tggacagcat gccagtcggc ctgttcgaaa cgctgctgcg caccggaggt
    32161 cacttcgagg aatcgaccat actgagcatc gaagccttgc aaaatggttt gagcaatcaa
    32221 taattccagg ccacgcggca tttagcgccc tcatcaggag cagagaattg ccggatgcgg
    32281 cgtaaacgcc ttatccagcc tacgttcggc aacggttgta ggcatgataa gacgcgcaag
    32341 cgtcgcatca ggcatcgtgc accgattgcc ggatgcggcg taaatgcctt atccggccta
    32401 cgttcggcaa cggctgtagg catgataaga cgcgcaagcg tcgcatcagg catcgtgcac
    32461 cgattgccgg atgcggcgtg aacgccttat ccggcctaca gtcagcaacg gttgttgttg
    32521 cttagaactg cgattcttca gtggagccgg tcagcgcggt gactgaagac gtgccgccct
    32581 gaataatagt cgtcacttta tcgaagtaac ctgtacccac ttcctgctgg tgagatacga
    32641 aggtatagcc atctttcgcg gcggcaaatt ccggctgctg cactttctca acgtagtgct
    32701 tcataccctc gccctgggca taggcgtttg ccaggtcaaa catgttgaac cacatgctgt
    32761 ggatacctgc cagggtgatg aactggaact tgtagcccat atccgacagc tgctgctgga
    32821 agctggcaat agttttgtcg tcgaggtttt tctgccagtt gaacgacggc gagcagttat
    32881 aagccagcag tttgcccgga tatttcgcgt ggatagcttg tgcaaagcga cgcgccagtt
    32941 ccagatccgg cgtggaggtt tcacaccaga ccaggtcagc atatggcgca tacgccaggc
    33001 cacggctgat cgcttgctca atgcccgcat gagtacggaa gaagccttca ctggtacgct
    33061 cgccggtaat aaattcgctg tcatacgggt cgcaatcgga ggtgatcaga tccgccgcat
    33121 cagcatcggt acgggcaacc agcagggttg gaacgcccgt cacgtcagct gccagacgcg
    33181 ccgcgaccag tttctgaata gcttcctgag ttggcactaa aactttgccg cccatgtgac
    33241 cgcatttctt cactgacgcc agctgatctt cgaagtgaac tgccgctgca ccggcttcaa
    33301 tcatcgcttt catcagttca aaggcattca ggacaccgcc aaaaccggct tccgcatcgg
    33361 caacgatcgg caggaagtaa tcgacatagc gcggatcgcc cggctcaatg cccgcggacc
    33421 attggatctg atcggcacga cggaaggtgt tgttgatccg ctccaccaca gctggcaccg
    33481 agtttgccgg atagagcgac tgatccggat acatgctggc cgccaggtta gcgtccgccg
    33541 ctacctgcca tcccgacaga tagactgctt caatacccgc tttcgcctgt tgcagcgcct
    33601 gaccgccagt cagtgcgccg aggctgttga tgtagccttt tttcgactca ccgtgcagca
    33661 gacgccacat tttcgctgcg cccagttgcg ccagcgtgca ttcaggattg actgaaccgc
    33721 gtaatttcac cacatcttcc gcactgtatg ggcgagtaat gccttcccaa cgcggttgag
    33781 tccactcttt ctgtaattct tcaatttgtt gtgtacgggt tttcatgtgc agatgctcca
    33841 tagttatgtg gtggtttacg ctaacaggcg gtagcctggc agggtcagga aatcaattaa
    33901 ctcatcggaa gtggtgatct gttccatcaa gcgtgcggca tcgtcaaaac gcccctggga
    33961 gaaacgttct tcgcccagtt cgctggcaat gactttcatc tcttcgccca gcatctggcg
    34021 gaacaaggct ttggtcaccg gtttgccatt gctcaacgtt ttttgatgat ggatccactg
    34081 ccagatcgag gtacgggaaa tttcagccgt cgccgcatct tccatcaggc cataaatcgg
    34141 cacacagccg ttgccagaga tccacgcttc gatgtactgc acagccacgc gaatgttggc
    34201 gcgcatacct tcttcggtgc gttcaccatc acaaggtgcc agcagctgat cggcagtaat
    34261 cggcgcgtct tgttcgcgca tcacttcaag ctgattttta cgggagccga gaatgtcgtt
    34321 gaataccgcc attgccgtgt ccgcaaggcc tgggtgagcg atccatgtgc catcgtgacc
    34381 gttattggct tccagcgatt tatccgcttt tactttgttg agcacctggt tattgtgctc
    34441 ttcatctttg ctcggaataa acgccgccat gccgcccatc gcaaaagcac cgcgtttatg
    34501 gcaggtttta atcaacaggc gtgagtaagc attcaggaat ggtttatcca tcgtcactgc
    34561 ctgtctgtct ggcaggacgc gatcgggata gtttttcaac gttttgatat agctgaagat
    34621 gtaatcccaa cgaccgcagt tcagaccaac aatatggtca cgcagcgcgt gaaggatttc
    34681 atccatctgg aacacggcgg gcagcgtttc aatcagcaac gtcgccttga tggtgccgcg
    34741 cggcagatta aagcgatctt ctgcatagct gaagacttcg ctccaccagg ccgcttcctg
    34801 ccaggactgg gttttcggca gatagaaata gggaccactg ccctttgcca acagtgcctg
    34861 atagttgtgg aagaaataga gcgcaaaatc aaacaggctg ccggggattg cctcaccacg
    34921 ccaggtgaca tgtttttccg gcaagtgcag accgcgtacc cgacaaatca aaaccgctgg
    34981 attgggcttg agctggtaaa ttttgcctgc ttcattggtg taactgatgg tgccgttaac
    35041 cgcatcacgc aggttaattt gcccgtcgat cactttgttc cagtctggtg ccagtgaatc
    35101 ttcgaaatcg gccataaaga ctttcacatt ggcgttgagc gcgttgatca ccatcttgcg
    35161 ctctaccggg ccagttatct ctacgcggcg gtcttctaag tccgcaggaa tcccgcgaat
    35221 tttccaatca gcatcgcgaa tggaagctgt ttccgaaata aaatcaggca acgttccgtt
    35281 atcaatatct tgctgctgct gaatgcgcgc tgccagaagt ttattgcgtt gtggcgtaaa
    35341 atgcgtcacc agctcagtca gaaattctac cgcttcggca gtaagaattt gcttctcctg
    35401 ctcgccatac ggccttgtga aagccagttc atcggttgtt gttgcctgtt cagtcatcgt
    35461 gcagctcctc gtcatggatc cgaaaacttc cccactgtga acgaaggatc gttgtgctct
    35521 tttcgttcag cacaactaag actactcatt taaaatgcaa aatcaaaaac aatttccatt
    35581 ttaattaaaa atacttgata acttgttgat aacaatatga ataaaattta ttcacctgct
    35641 gaggtacgtt tcggaaataa aaaaggcacc cgaaggtgcc tgaggtaagg tgctgaatcg
    35701 cttaacgatc gactatcaca gaagattaat ccagcgttgg attcatgtgc cgtagatcgt
    35761 atggcgtgat ctggtagacg taatagttga gccagttggt aaacagtaaa ttaccgtgac
    35821 tacgccagct cgctcgcggt gtattttgcg gatcattgtg cgggaaatag ttatacggta
    35881 catccgggtc tagtccggct tccacatcgc ggaaaaattc ctgcgccagc gtttgcgcat
    35941 catattcggg atggcccgtc acaaaggcaa tgcgcttatc tttactggca aacagatatg
    36001 catccccttc ttccgtctct gccagaattt ccagatcggt gtaatcacga atcaacgctg
    36061 ccggaaagtc agcatagcgc gaatgcggtg ccaggaatga atcatcaaag ccacgcgtca
    36121 gaagcgcatg aggatggaga atatgatgct cgtaaacgcc agagagtttg tcggtgcgag
    36181 tttgcttagg aatgccgtag aggatattga gcgcggcctg taccgcccag cagacaaaca
    36241 gcgtcgaggt gacgtgatct ttcgaccact ccagcacctg tttgatctgc ggccagtaag
    36301 cgacatcatt aaactccacc aggcccagcg gcgcaccagt tacaatcaaa ccgtcaaagt
    36361 tctgatcctg aatatcttca aagttacagt agaagttgtt cagatgctct gcgggcgtgt
    36421 tgcgcgattc acgggaatcg atgcgcaaca gctgaatatc gacctgcaaa ggtgagtttg
    36481 aaagcaggcg cagaaactga ttttcagttt caatcttctt cggcatcagg ttaaggatca
    36541 gaaccttaag tggacgaatt tcctgaccag acgcacgaga agttgtcatc acaaagacgt
    36601 tttcttcacg caagaaattg acggcgggta gctcgtccgg cacacgaatc ggcataacct
    36661 gattacctca ctacatacgc ttatacgttt agacatccag atagctgaag ataaccagaa
    36721 aatttgccaa tgtcgagcct gcatgttgaa ggtgagaaag tttcaaggaa aagactacgt
    36781 tagaatataa gaatgactaa aaggagagaa aatggttatt agtattcgcc gctcacggca
    36841 tgaggaaggg gaggaactcg ttgcgatttg gtgtcgttct gtcgatgcca ctcacgattt
    36901 tctatcagca gagtatcgga ccgagctgga ggacctagtt cgttccttcc tgccggaagc
    36961 gccgttgtgg gtcgcggtta atgagcggga tcagccggtt ggatttatgt tgctaagtgg
    37021 gcagcatatg gatgcgctgt ttatcgatcc tgatgtgcgc ggctgcggcg taggtcgggt
    37081 gctggtggag catgcgctct cgatggcacc ggaactgaca accaacgtta atgagcaaaa
    37141 tgagcaggcg gttgggttct ataagaaggt gggttttaag gttacgggac gctctgaggt
    37201 ggacgatttg gggaaaccgt atccgttgct gaatctggcg tatgtggggg cgtaggcgat
    37261 tttttctcat cccggtgggc tgaacttcag gtttagtacc caccaatggt gacacgatta
    37321 tttctgctta agcattgcca tgaccgcact atcactgagt accgctgatt gcgcatggat
    37381 gtggaactgg cgatatttca ttaacgttgc cccagcgacc acttcatgga gaatgcgttc
    37441 ctcaacctgt gacaaaccgc cctcattcat ttccagcgcg ctcacaacaa tatccatacg
    37501 ttttgctggc aaaaaagaat gccaggttga acgtgggtgg agttgcagaa caagatcttg
    37561 cagaactttt tctgcaacaa agaaattggc gattaacagg cgctggttac tgaaggcagc
    37621 gtctcctgac acttcacgtt tgctttcaag atcgcgaaca gtaatttgat tacgacgaat
    37681 ttggatatac agaactgaca tgagattccc ttcatcatgc aaataattga tatgcaaaaa
    37741 accccggcct tatggaccgg ggtttttcta atttgatgcc tggcagttcc ctactctcgc
    37801 atggggagac cccacactac catcggcgct acggcgtttc acttctgagt tcggcatggg
    37861 gtcaggtggg accaccgcgc tactgccgcc aggcaaattc tgttttatca gaccgcttct
    37921 gcgttctgat ttaatctgta tcaggctgaa aatcttctct catccgccaa aaca
//
LOCUS       DAPOAV010000040        37969 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.040, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000040 DAPOAV010000000
VERSION     DAPOAV010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37969
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.040"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(114..401)
                     /locus_tag="RN951_002291"
     CDS             complement(114..401)
                     /locus_tag="RN951_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebO family protein"
                     /protein_id="HDX2527281.1"
                     /translation="MNEVVNSGVMNIASLVVSVVVLLIGLILWFFINRASSRTNEQIE
                     LLEALLDQQKRQNALLRRLCEANEPEKADKKTVESQKSVEDEDIIRLVAER"
     gene            complement(476..619)
                     /gene="mgrB"
                     /locus_tag="RN951_002292"
     CDS             complement(476..619)
                     /gene="mgrB"
                     /locus_tag="RN951_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP/PhoQ regulator MgrB"
                     /protein_id="HDX2527282.1"
                     /translation="MKKFRWVVLVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQF
                     IPW"
     gene            778..1017
                     /locus_tag="RN951_002293"
     CDS             778..1017
                     /locus_tag="RN951_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527283.1"
                     /translation="MRFIIRTVMLIALVWIGLLLSGYGVLIGSKENAAGLGLQCTYLT
                     ARGTSTVQYLHTKSGFLGITDCPLLRKSNIVVDNG"
     gene            complement(1161..1952)
                     /gene="kdgR"
                     /locus_tag="RN951_002294"
     CDS             complement(1161..1952)
                     /gene="kdgR"
                     /locus_tag="RN951_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator KdgR"
                     /protein_id="HDX2527284.1"
                     /translation="MANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMS
                     KSTVYRFLQTMKTLGYVAQEGESEKYSLTLKLFELGARALQNVDLIRSADIQMRELSR
                     LTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRDEV
                     KQILEGVEYKRSTERTITSTEALLPVLDQVREQGYGEDNEEQEEGLRCIAVPVFDRFG
                     VVIAGLSISFPTLRFSEERLQEYVAMLHTAARKISAQMGYHDYPF"
     gene            2129..3502
                     /locus_tag="RN951_002295"
     CDS             2129..3502
                     /locus_tag="RN951_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416342.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2527285.1"
                     /translation="MPKVQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIAT
                     DLHATPASSIWVVNAYQIAIVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSD
                     SLQMLTLARVIQGFGGAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIA
                     AAILSIASWKWLFLINVPLGIIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLL
                     ITALSGFAQGQSLTLIAAELVVMVVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICT
                     SVCSFCAQMLAMVSLPFYLQTVLGRSEVETGLLLTPWPLATMVMAPLAGYLIERVHAG
                     LLGALGLFIMAAGLFSLVLLPASPADINIIWPMILCGAGFGLFQSPNNHTIITSAPRE
                     RSGGASGMLGTARLLGQSSGAALVALMLNQFGDNGTHVSLMAAAILAVIAACVSGLRI
                     TQPRSRA"
     gene            complement(3548..4429)
                     /gene="htpX"
                     /locus_tag="RN951_002296"
     CDS             complement(3548..4429)
                     /gene="htpX"
                     /locus_tag="RN951_002296"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014229823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease HtpX"
                     /protein_id="HDX2527286.1"
                     /translation="MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLMIMALLFGF
                     GGSFVSLLMSKWMALRSVGGEVIEQPRNERERWLVNTVATQARQAGIAMPQVAIYHAP
                     DINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVN
                     TFVIFISRILAQLAAGFMGGNRDEGEESNGNPLIYFAVATVLELVFGILASIITMWFS
                     RHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMALCINGKSKSLSELFMTH
                     PPLDKRIEALRTGEYLK"
     gene            complement(4621..6669)
                     /gene="prc"
                     /locus_tag="RN951_002297"
     CDS             complement(4621..6669)
                     /gene="prc"
                     /locus_tag="RN951_002297"
                     /EC_number="3.4.21.102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy terminal-processing peptidase"
                     /protein_id="HDX2527287.1"
                     /translation="MNMFFRLTALAGLLAIAGQTFAVEDITRADQIPVLKEETQHATV
                     SERVTSRFTRSHYRQFELDQAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTELGD
                     ELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEA
                     ELNALWDSKVKFDELSLKLTGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAF
                     AREIDPHTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAI
                     SVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRTVTLT
                     RERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDL
                     RSNGGGALTEAVSLSGLFIPAGPIVQVRDNNGKVREDSDTDGQVFYKGPLVVLVDRFS
                     ASASEIFAAAMQDYGRALVVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTI
                     QKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVKSGDLTA
                     FEPELLKEHNARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRL
                     ARLNERFKREGKPELKKLDDLPKDYQEPDPYLDETVNIALDLAKLEKARPAEQPAPVK
                     "
     gene            complement(6689..7387)
                     /gene="proQ"
                     /locus_tag="RN951_002298"
     CDS             complement(6689..7387)
                     /gene="proQ"
                     /locus_tag="RN951_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone ProQ"
                     /protein_id="HDX2527288.1"
                     /translation="MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVD
                     RVAGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATRVDLDGNPCGELDEQHVEHARKQ
                     LEEAKARVQAQRAEQQAKKREAAATAGEKEDAPRRERKPRPTTPRRKEGAERKPRAQK
                     PVEKAPKTVKAPREEQHTPVSDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLN
                     SGMSLIVRAEHLVF"
     gene            complement(7484..7981)
                     /gene="msrC"
                     /locus_tag="RN951_002299"
     CDS             complement(7484..7981)
                     /gene="msrC"
                     /locus_tag="RN951_002299"
                     /EC_number="1.8.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416346.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine (R)-S-oxide reductase"
                     /protein_id="HDX2527289.1"
                     /translation="MNKTEFYADLNRDFNALMAGETSFLATLANTSALLYERLTDINW
                     AGFYLLEDDTLVLGPFQGKIACVRIPVGRGVCGTAVARNQVQRIEDVHVFDGHIACDA
                     ASNSEIVLPLVVKNQIIGVLDIDSTVFGRFTDEDEQGLRQLVALLEKVLATTDYKKFF
                     ASVAG"
     gene            8111..9394
                     /gene="yebS"
                     /locus_tag="RN951_002300"
     CDS             8111..9394
                     /gene="yebS"
                     /locus_tag="RN951_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity lipid transport subunit YebS"
                     /protein_id="HDX2527290.1"
                     /translation="MALNTPQITPTKKITVRAIGEELPRGDYQRCPQCDMLFSLPEIN
                     SHQSAYCPRCQAKIRDGRDWSLTRLAAMAFTMLLLMPFAWGEPLLHIWLLGIRIDANV
                     MQGIWQMTKQGDAITGSMVFFCVIGAPLILVTSIAYLWFGNRLGMNLRPVLLMLERLK
                     EWVMLDIYLVGIGVASIKVQDYAHIQAGVGLFSFVALVILTTVTLSHLNVEELWERFY
                     PQRPATRRDEKLRVCLGCHFTGYPDQRGRCPRCHIPLRLRRRHSLQKCWAALLASIVL
                     LLPANLLPISIIYLNGGRQEDTILSGIMSLASSNIAVAGIVFIASILVPFTKVIVMFT
                     LLLSIHFKCQQGLRTRILLLRMVTWIGRWSMLDLFVISLTMSLINRDQILAFTMGPAA
                     FYFGAAVILTILAVEWLDSRLLWDAHESGNARFDD"
     gene            9363..11996
                     /gene="yebT"
                     /locus_tag="RN951_002301"
     CDS             9363..11996
                     /gene="yebT"
                     /locus_tag="RN951_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416348.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-binding membrane homeostasis protein YebT"
                     /protein_id="HDX2527291.1"
                     /translation="MSQETPASTTEAQIKNKRRISPFWLLPFIALMIASWLIWDSYQD
                     RGNTVTIDFMSADGIVPGRTPVRYQGVEVGTVQDISLSDDLRKIEVKVSIKSDMKDAL
                     REETQFWLVTPKASLAGVSGLDALVGGNYIGMMPGKGKEQDHFVALDTQPKYRLDNGD
                     LMIHLQAPDLGSLNSGSLVYFRKIPVGKVYDYAINPNKQGVVIDVLIERRFTDLVKKG
                     SRFWNVSGVDANVSISGAKVKLESLAALVNGAIAFDSPEESKPAEAEDTFGLYEDLAH
                     SQRGVIIKLELPSGAGLTADSTPLMYQGLEVGQLTKLDLNPGGKVTGEMTVDPSVVTL
                     LRENTRIELRNPKLSLSDANLSALLTGKTFELVPGDGEPRKEFVVVPGEKALLHEPDV
                     LTLTLTAPESYGIDAGQPLILHGVQVGQVIDRKLTSKGVTFTVAIEPQHRELVKGDSK
                     FVVNSRVDVKVGLDGVEFLGASASEWINGGIRILPGDKGEMKASYPLYANLEKALENS
                     LSDLPTTTVSLSAETLPDVQAGSVVLYRKFEVGEVITVRPRANAFDIDLHIKPEYRNL
                     LTSNSVFWAEGGAKVQLNGSGLTVQASPLSRALKGAISFDNLSGASASQRKGDKRILY
                     ASETAARAVGGQITLHAFDAGKLAVGMPIRYLGIDIGQIQTLDLITARNEVQAKAVLY
                     PEYVQTFARGGTRFSVVTPQISAAGVEHLDTILQPYINVEPGRGNPRRDFELQEATIT
                     DSRYLDGLSIIVEAPEAGSLGIGTPVLFRGLEVGTVTGMTLGTLSDRVMIAMRISKRY
                     QHLVRNNSVFWLASGYSLDFGLTGGVVKTGTFNQFIRGGIAFATPPGTPLAPKAQEGK
                     HFLLQESEPKEWREWGTALPK"
     gene            12076..13515
                     /gene="rsmF"
                     /locus_tag="RN951_002302"
     CDS             12076..13515
                     /gene="rsmF"
                     /locus_tag="RN951_002302"
                     /EC_number="2.1.1.178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416349.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1407)-C(5))-methyltransferase
                     RsmF"
                     /protein_id="HDX2527292.1"
                     /translation="MAQHTVYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVN
                     TLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERDNEDALPLGSTAEHLSGLFYIQEA
                     SSMLPVAALFADGNAPQRVMDVAAAPGSKTTQISARMNNEGAILANEFSASRVKVLHA
                     NISRCGISNVALTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESN
                     QEIAATQRELIDSAFHALRPGGTLVYSTCTLNQEENEAVCLWLKETYPDAVEFLPLGD
                     LFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPAPKYKVGNFPFSPVKD
                     REAGQIRQAATGVGLNWDENLRLWQRDKELWLFPVGIEALIGKVRFSRLGIKLAETHN
                     KGYRWQHEAVIALASPDNMNAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPI
                     GLAKRIGSRLKNSYPRELVRDGKLFTGNA"
     gene            13633..13869
                     /locus_tag="RN951_002303"
     CDS             13633..13869
                     /locus_tag="RN951_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707284.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1480 family protein"
                     /protein_id="HDX2527293.1"
                     /translation="MKTSVRIGAFEIDDGELHGESPGDRTLTIPCKSDPDLCMQLDAW
                     DAETSIPALLNGEHSVLYRTRYDQQSDAWIMRLA"
     gene            13974..14165
                     /locus_tag="RN951_002304"
     CDS             13974..14165
                     /locus_tag="RN951_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebW family protein"
                     /protein_id="HDX2527294.1"
                     /translation="MFALVLFVCYLDGGCEDIVVDVYNTEQQCLYSMSDQRIRQGGCF
                     PIEDFIDGFWRPAQEYGDF"
     gene            complement(14166..14822)
                     /gene="pphA"
                     /locus_tag="RN951_002305"
     CDS             complement(14166..14822)
                     /gene="pphA"
                     /locus_tag="RN951_002305"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416352.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HDX2527295.1"
                     /translation="MKQPAPVYQRIAGHQWRHIWLSGDIHGCLEQLRRKLWHCRFDPW
                     RDLLISVGDVIDRGPQSLRCLQLLEQHWVCAVRGNHEQMAMDALASQQMSLWLMNGGD
                     WFIALADNQQKQAKTALEKCQHLPFILEVHSRTGKHVIAHADYPDDVYEWQKDVDLHQ
                     VLWSRSRLGERQKGQGITGADHFWFGHTPLRHRVDIGNLHYIDTGAVFGGELTLVQLQ
                     "
     gene            complement(15218..15559)
                     /locus_tag="RN951_002306"
     CDS             complement(15218..15559)
                     /locus_tag="RN951_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebY family protein"
                     /protein_id="HDX2527296.1"
                     /translation="MMKKSILAFLLLTSSAAALAAPQVITVSRFEVGKDKWAFNREEV
                     MLTCRPGNALYVINPSTLVQYPLNDIAQKEVASGKTNAQPISVIQIDDPNNPGEKMSL
                     APFIERAEKLC"
     gene            complement(15572..16444)
                     /gene="copD"
                     /locus_tag="RN951_002307"
     CDS             complement(15572..16444)
                     /gene="copD"
                     /locus_tag="RN951_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis membrane protein CopD"
                     /protein_id="HDX2527297.1"
                     /translation="MLAFTWIALRFIHFTSLMLVFGFAMYGAWLAPLTIRRLLAKRFL
                     RLQQHAAVWSLISATAMLAVQGGLMGTGWTDVFSPNIWQAVLQTQFGGIWLWQIVLAL
                     VTLIVALMQPRNMPRLLFMITTAQFILLAGVGHATLNEGVTAKIHQTNHAIHLICAAA
                     WFGGLLPVLWCMQLIKGRWRHQAIQALMRFSWCGHFAVIGVLASGVLNALLITGFPPT
                     LTTYWGQLLLLKAILVMIMVVIALANRYVLVPRMRQDEDRAAPWFVWMTKLEWAIGAV
                     VLVIISLLATLEPF"
     gene            complement(16448..16822)
                     /gene="yobA"
                     /locus_tag="RN951_002308"
     CDS             complement(16448..16822)
                     /gene="yobA"
                     /locus_tag="RN951_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopC domain-containing protein YobA"
                     /protein_id="HDX2527298.1"
                     /translation="MASTARSLRYALAILTTSLVTPSVWAHAHLTHQYPAANAQVTAA
                     PQAITLNFSEGVETGFSGAKITGPKNENIKTLPAKRNEQDQKQLIVPLADSLKPGTYT
                     VDWHVVSVDGHKTKGHYTFSVK"
     gene            16961..17191
                     /gene="holE"
                     /locus_tag="RN951_002309"
     CDS             16961..17191
                     /gene="holE"
                     /locus_tag="RN951_002309"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit theta"
                     /protein_id="HDX2527299.1"
                     /translation="MLKNLAKLDQTEMDKVNVDLAAAGVAFKERYNMPVIAEAVEREQ
                     PEHLRSWFRERLIAHRLASVNLSRLPYEPKLK"
     gene            17293..17949
                     /locus_tag="RN951_002310"
     CDS             17293..17949
                     /locus_tag="RN951_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HDX2527300.1"
                     /translation="MSFWKVAAAQYEPRKTSLTEQVAHHLEFVRAAARQQCQLLVFPS
                     LSLLGCDYSRRALPAPPDLSLLDPLCYAATTWRMTIIAGLPVEYNDRFIRGIAVFAPW
                     RKTPGIYHQSHGACLGRRSRTITVVDEQPQGMDMDPTCSLFTTGQCLGEPDLLASARR
                     LQFFSHQYSIAVLMANARGNSALWDEYGRLIVRADRGSLLLVGQRSSQGWQGDIIPLR
                     "
     gene            17973..18635
                     /gene="exoX"
                     /locus_tag="RN951_002311"
     CDS             17973..18635
                     /gene="exoX"
                     /locus_tag="RN951_002311"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease X"
                     /protein_id="HDX2527301.1"
                     /translation="MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVRPDRPIS
                     PQAMAIHRITEAMVADKPWIEDVIPHYYGSEWYVAHNASFDRRVLPEMPGEWICTMKL
                     ARRLWPGIKYSNMALYKTRKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQ
                     MADITGRPSLMTTFTFGKYRGKAVSDVAERDPGYLRWLFNNLDSMSPELRLTLKHYLE
                     NT"
     gene            complement(18632..20692)
                     /gene="ptrB"
                     /locus_tag="RN951_002312"
     CDS             complement(18632..20692)
                     /gene="ptrB"
                     /locus_tag="RN951_002312"
                     /EC_number="3.4.21.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase B"
                     /protein_id="HDX2527302.1"
                     /translation="MLPKAARIPHAMTLHGDTRIDNYYWLRDDTRSQPEVLDYLQQEN
                     SYGHRVMASQQALQDRILKEIIDRIPQREVSAPYIKNGYRYRHIYEPGCEYAIYQRQS
                     AFSEEWDEWETLLDANKRAAHSEFYSMGGMAITPDNTIMALAEDFLSRRQYGIRFRNL
                     ETGNWYPELLDNVEPSFVWANDSWIFYYVRKHPVTLLPYQVWRHAIGTPASQDKLIYE
                     EKDDTYYVSLHKTTSKHYVVIHLASATTSEVRLLDAEMADAEPFVFLPRRKDHEYSLD
                     HYQHRFYLRSNRHGKNFGLYRTRMRDEQQWEELIPPRENIMLEGFTLFTDWLVVEERQ
                     RGLTSLRQINRKTREVIGIAFDDPAYVTWIAYNPEPETARLRYGYSSMTTPDTLFELD
                     MDTGERRVLKQTEVPGFYAANYRSEHLWIVARDGVEVPVSLVYHRKHFRKGHNPLLVY
                     GYGSYGASIDADFSFSRLSLLDRGFVYAIVHVRGGGELGQQWYEDGKFLKKKNTFNDY
                     LDACDALLKLGYGSPSLCYAMGGSAGGMLMGVAINQRPELFHGVIAQVPFVDVVTTML
                     DESIPLTTGEFEEWGNPQDPQYYEYMKSYSPYDNVTAQAYPHLLVTTGLHDSQVQYWE
                     PAKWVAKLRELKTDDHLLLLCTDMDSGHGGKSGRFKSYEGVAMEYAFLVALAQGTLPA
                     TPAD"
     gene            complement(20901..21560)
                     /locus_tag="RN951_002313"
     CDS             complement(20901..21560)
                     /locus_tag="RN951_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance TerB family protein"
                     /protein_id="HDX2527303.1"
                     /translation="MANWLNQLQSLLGQSSSSTSSSADQGLVKLLVPGALGGLAGLLV
                     ANKSARKLLTKYGTNALLVGGGAVAGTVLWNKYKDKIRAAHQDEPQFGAQSTPLDERT
                     ARLILALVFAAKSDGHIDAKERAAIDQQLRGAGVEEQGRVLIEQAIEQPLDPQRLATG
                     VRNEEEALEIYFLSCAAIDIDHFMERSYLNALGDALKIPQDVRDGIERDLEQQKRTLA
                     E"
     gene            complement(21887..22243)
                     /locus_tag="RN951_002314"
     CDS             complement(21887..22243)
                     /locus_tag="RN951_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310584.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YebF"
                     /protein_id="HDX2527304.1"
                     /translation="MKKRGAFLGLLLVSACASVFAANNETSKSVTFPKCEGLDAAGIA
                     ASVKRDYQQNRVARWADDQKIVGQADPVAWVSLQDIQGKDDKWSVPLTVRGKSADIHY
                     QVSVDCKAGMAEYQRR"
     gene            complement(22310..22600)
                     /gene="yebG"
                     /locus_tag="RN951_002315"
     CDS             complement(22310..22600)
                     /gene="yebG"
                     /locus_tag="RN951_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein YebG"
                     /protein_id="HDX2527305.1"
                     /translation="MAVEVKYVVIREGEEKMSFTSKKEADAYDKMLDTADLLDTWLTN
                     SPVQMEDEQREALSLWLAEQKDVLSTILKTGKLPSPQVVGAESEEEDASHAA"
     gene            22734..23912
                     /gene="purT"
                     /locus_tag="RN951_002316"
     CDS             22734..23912
                     /gene="purT"
                     /locus_tag="RN951_002316"
                     /EC_number="2.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent phosphoribosylglycinamide
                     formyltransferase"
                     /protein_id="HDX2527306.1"
                     /translation="MTLLGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRY
                     ADAPAMHVAHRSHVINMLDGDALRRVVELEKPHYIVPEIEAIATDMLIQLEEEGLNVV
                     PCARATKLTMNREGIRRLAAEELQLPTSTYRFADSESLFREAVADIGYPCIVKPVMSS
                     SGKGQTFIRSAEQLAQAWKYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFC
                     APVGHRQEDGDYRESWQPQQMSPLALERAQEIARKVVLALGGYGLFGVELFVCGDEVI
                     FSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGLPVGGIRQYGPAASAVILPQLTSQN
                     VTFDNVQNAVGADLQIRLFGKPEIDGSRRLGVALATAESVVDAIERAKHAAGQVKVQG
                     "
     gene            complement(23968..24609)
                     /gene="kdgA"
                     /locus_tag="RN951_002317"
                     /gene_synonym="eda"
     CDS             complement(23968..24609)
                     /gene="kdgA"
                     /locus_tag="RN951_002317"
                     /gene_synonym="eda"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HDX2527307.1"
                     /translation="MKNWKTSAESILTTGPVVPVIVVKKLEHAVPMAKALVAGGVRVL
                     EVTLRTECAVDAIRAIAKEVPEAIVGAGTVLNPQQLAEVTEAGAQFAISPGLTEPLLK
                     AATEGTIPLIPGISTVSELMLGMDYGLKEFKFFPAEANGGVKALQAIAGPFSQVRFCP
                     TGGISPANYRDYLALKSVLCIGGSWLVPADALEAGDYDRITKLAREAVEGAKL"
     gene            complement(24646..26457)
                     /gene="edd"
                     /locus_tag="RN951_002318"
     CDS             complement(24646..26457)
                     /gene="edd"
                     /locus_tag="RN951_002318"
                     /EC_number="4.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydratase"
                     /protein_id="HDX2527308.1"
                     /translation="MNPQLLRVTNRIIERSRETRSAYLARIEQAKTSTVHRSQLACGN
                     LAHGFAACQPEDKASLKSMLRNNIAIITSYNDMLSAHQPYEHYPEIIRKALHEANAVG
                     QVAGGVPAMCDGVTQGQDGMELSLLSREVIAMSAAVGLSHNMFDGALFLGVCDKIVPG
                     LTMAALSFGHLPAVFVPSGPMASGLPNKEKVRIRQLYAEGKVDRMALLESEAASYHAP
                     GTCTFYGTANTNQMVVEFMGMQLPGSSFVHPDSPLRDALTAAAARQVTRMTGNGNEWM
                     PIGKMIDEKVVVNGIVALLATGGSTNHTMHLVAMARAAGIQINWDDFSDLSDVVPLMA
                     RLYPNGPADINHFQAAGGVPVLVRELLKAGLLHEDVNTVAGFGLSRYTLEPWLNNGEL
                     DWREGAEKSLDSNVIASFEQPFSHHGGTKVLSGNLGRAVMKTSAVPVENQVIEAPAVV
                     FESQHDVMPAFEAGLLDRDCVVVVRHQGPKANGMPELHKLMPPLGVLLDRCFKIALVT
                     DGRLSGASGKVPSAIHVTPEAYDGGLLAKVRDGDIIRVNGQTGELTLLVDEAELAARE
                     PHIPDLSASRVGTGRELFSALREKLSGAEQGATCITF"
     gene            complement(26692..28167)
                     /gene="zwf"
                     /locus_tag="RN951_002319"
     CDS             complement(26692..28167)
                     /gene="zwf"
                     /locus_tag="RN951_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HDX2527309.1"
                     /translation="MAVTQTAQACDLVIFGAKGDLARRKLLPSLYQLEKAGQLNPDTR
                     IIGVGRADWDKAAYTKVVREALETFMKETIDEGLWDTLSARLDFCNLDVNDTAAFSRL
                     GAMLDQKNRITINYFAMPPSTFGAICKGLGEAKLNAKPARVVMEKPLGTSLATSQEIN
                     DQVGEYFEECQVYRIDHYLGKETVLNLLALRFANSLFVNNWDNRTIDHVEITVAEEVG
                     IEGRWGYFDKAGQMRDMIQNHLLQILCMIAMSPPSDLSADSIRDEKVKVLKSLRRIDR
                     SNVREKTVRGQYTAGFAQGKKVPGYLEEEGANKSSNTETFVAIRVDIDNWRWAGVPFY
                     LRTGKRLPTKCSEVVVYFKTPELNLFKESWQDLPQNKLTIRLQPDEGVDIQVLNKVPG
                     LDHKHNLQITKLDLSYSETFNQTHLADAYERLLLETMRGIQALFVRRDEVEEAWKWVD
                     SITEAWAMDNDAPKPYQAGTWGPVASVAMITRDGRSWNEFE"
     gene            28505..29374
                     /gene="hexR"
                     /locus_tag="RN951_002320"
                     /gene_synonym="yebK"
     CDS             28505..29374
                     /gene="hexR"
                     /locus_tag="RN951_002320"
                     /gene_synonym="yebK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HexR"
                     /protein_id="HDX2527310.1"
                     /translation="MNMLEKIQSQLEHLSKSERKVAEVILASPDNAIHSSIAAMALEA
                     NVSEPTVNRFCRSMDTRGFPDFKLHLAQSLANGTPYVNRNVNEDDSVESYTGKIFESA
                     MATLDHVRHSLDKSAINRAVDLLTQAKKIAFFGLGSSAAVAHDAMNKFFRFNVPVVYS
                     DDIVLQRMSCMNCSDGDVVVLISHTGRTKNLVELAQLARENDAMVIALTSAGTPLARE
                     ATLAITLDVPEDTDIYMPMVSRLAQLTVIDVLATGFTLRRGAKFRDNLKRVKEALKES
                     RFDKQLLNLSDDR"
     gene            29502..30944
                     /gene="pyk"
                     /locus_tag="RN951_002321"
     CDS             29502..30944
                     /gene="pyk"
                     /locus_tag="RN951_002321"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HDX2527311.1"
                     /translation="MSRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSP
                     EDHKMRADKVREIAAKLGRHVAILGDLQGPKIRVSTFKEGKVFLNIGDKFLLDANLGK
                     GEGDKEKVGIDYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNK
                     GINKLGGGLSAEALTEKDKADIKTAALIGVDYLAVSFPRCGEDLNYARRLARDAGCDA
                     KIVAKVERAEAVCSQDAMDDIILASDVVMVARGDLGVEIGDPELVGIQKALIRRARQL
                     NRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAM
                     ARVCLGAEKIPSINVSKHRLDVQFDNVEEAIAMSAMYAANHLKGVTAIITMTESGRTA
                     LMTSRISSGLPIFAMSRHERTLNLTALYRGVTPVHFDSANDGVAAASEAVNLLRDKGY
                     LMSGDLVIVTQGDVMSTVGSTNTTRILTVE"
     gene            complement(31075..32046)
                     /gene="lpxM"
                     /locus_tag="RN951_002322"
                     /gene_synonym="msbB"
     CDS             complement(31075..32046)
                     /gene="lpxM"
                     /locus_tag="RN951_002322"
                     /gene_synonym="msbB"
                     /EC_number="2.3.1.243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416369.1"
                     /note="LpxM is lauroyl-Kdo(2)-lipid IV(A)
                     myristoyltransferase, an enzyme characterized in
                     Escherichia coli and involved in biosynthesis of the form
                     of lipid A found in that species and some closely related
                     species; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase"
                     /protein_id="HDX2527312.1"
                     /translation="METKKNNSEYIPEFDKSFRHPRYWGAWLGVAAMAGIALTPPKFR
                     DPILARLGRFAGRLGKSSRRRALINLSLCFPERSEAEREAIVDEMFATAPQAMAMMAE
                     LAIRGPEKIQPRVDWQGLEIIEEMRRNNEKVIFLVPHGWAVDIPAMLMASQGQKMAAM
                     FHNQGNPVFDYVWNTVRRRFGGRLHARNDGIKPFIQSVRQGYWGYYLPDQDHGPEHSE
                     FVDFFATYKATLPAIGRLMKVCRARVVPLFPIYDGKTHRLTIQVRPPMDDLLEADDHT
                     IARRMNEEVEIFVGPRPEQYTWILKLLKTRKPGEIQPYKRKDLYPIK"
     gene            complement(32166..33488)
                     /gene="mepM"
                     /locus_tag="RN951_002323"
     CDS             complement(32166..33488)
                     /gene="mepM"
                     /locus_tag="RN951_002323"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein DD-endopeptidase MepM"
                     /protein_id="HDX2527313.1"
                     /translation="MQQIARSVALAFNNLPRPHRVMLGSLTVLTLAVAVWRPYVYHRD
                     ATPIVKTIELEQNEIRSLLPEASEPIDQAAQEDEAIPQDELDDKIAGEAGVHEYVVST
                     GDTLSSILNQYGIDMGDITQLAAADKELRNLKIGQQLSWTLTADGELQRLTWEVSRRE
                     TRTYDRTAANGFKMTSEMQQGEWVNNLLKGTVGGSFVASARNAGLTSAEVSAVIKAMQ
                     WQMDFRKLKKGDEFAVLMSREMLDGKREQSQLLGVRLRSEGKDYYAIRAEDGKFYDRN
                     GTGLAKGFLRFPTAKQFRISSNFNPRRTNPVTGRVAPHRGVDFAMPQGTPVLSVGDGE
                     VVVAKRSGAAGYYVAIRHGRSYTTRYMHLRKILVKPGQKVKRGDRIALSGNTGRSTGP
                     HLHYEVWINQQAVNPLTAKLPRTEGLTGSDRREFLAQAKEIVPQLRFD"
     gene            complement(33504..34436)
                     /gene="znuA"
                     /locus_tag="RN951_002324"
     CDS             complement(33504..34436)
                     /gene="znuA"
                     /locus_tag="RN951_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416371.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     ZnuA"
                     /protein_id="HDX2527314.1"
                     /translation="MLHKKTLLFAALSAALWGGATQAADAAVVASLKPVGFIASAIAD
                     GVTETEVLLPDGASEHDYSLRPSDVKRLQNADLVVWVGPEMEAFMQKPVSKLPGAKQV
                     TIAQLEDVKPLLMKSIHGDDDDHDHAEKSDEDHHHGDFNMHLWLSPEIARATAVAIHG
                     KLVELMPQSRAKLDANLKDFEAQLASTETQVGNELAPLKGKGYFVFHDAYGYFEKQFG
                     LTPLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVESVARGTSVRMG
                     TLDPLGTNIKLGKTSYSEFLSQLANQYASCLKGD"
     gene            34515..35270
                     /gene="znuC"
                     /locus_tag="RN951_002325"
     CDS             34515..35270
                     /gene="znuC"
                     /locus_tag="RN951_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter ATP-binding protein ZnuC"
                     /protein_id="HDX2527315.1"
                     /translation="MTSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKS
                     TLVRVVLGLVTPDEGVIKRNGKLRIGYVPQKLYLDTTLPLTVNRFLRLRPGTHKEDIL
                     PALKRVQAGHLINAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALY
                     DLIDQLRRELDCGVLMVSHDLHLVMAKTDEVLCLNHHICCSGTPEVVSLHPEFISMFG
                     PRGAEQLGIYRHHHNHRHDLQGRIVLRRGNDRS"
     gene            35267..36052
                     /gene="znuB"
                     /locus_tag="RN951_002326"
     CDS             35267..36052
                     /gene="znuB"
                     /locus_tag="RN951_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter permease subunit ZnuB"
                     /protein_id="HDX2527316.1"
                     /translation="MIELLFPGWLAGIMLACAAGPLGSFVVWRRMSYFGDTLAHASLL
                     GVACGLLLDVNPFYAVIAVTLLLAGGLVWLEKRPQLAIDTLLGIMAHSALSLGLVVVS
                     LMSNIRVDLMAYLFGDLLAVTPEDLISIAIGVVIVVAILFWQWRNLLSMTISPDLAFV
                     DGVKLQRVKLLLMLVTALTIGVAMKFVGALIITSLLIIPAATARRFARTPEQMAGVAV
                     LVGMVAVTGGLTFSAVYDTPAGPSVVLCAALLFILSMMKKQAS"
     gene            complement(36199..37209)
                     /gene="ruvB"
                     /locus_tag="RN951_002327"
     CDS             complement(36199..37209)
                     /gene="ruvB"
                     /locus_tag="RN951_002327"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HDX2527317.1"
                     /translation="MIEADRLISAGTTLPEDVADRAIRPKLLEEYVGQPQVRSQMEIF
                     IKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLT
                     NLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGA
                     TTRAGSLTSPLRDRFGIVQRLEFYQVPDLQYIVSRSARFMGLEMSDDGALEVARRARG
                     TPRIANRLLRRVRDFAEVKHDGTISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKF
                     FGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATTRAWNHFGITPPE
                     MP"
     gene            complement(37218..37829)
                     /gene="ruvA"
                     /locus_tag="RN951_002328"
     CDS             complement(37218..37829)
                     /gene="ruvA"
                     /locus_tag="RN951_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012131997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HDX2527318.1"
                     /translation="MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQE
                     AIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAV
                     EREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAE
                     QEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL"
BASE COUNT         9106 a         9794 c         9366 g         9703 t
ORIGIN      
        1 atttgaagtc agaccagagt tttaatttga agcagttgca ccatgacagt gcgtataatc
       61 aggatgaatt gagtaaccct tcaacgacgg ggttactcaa gattgaggaa ggattatcgt
      121 tcggcgacca gacgaataat atcttcgtct tcaaccgatt tttgactctc aacggtcttt
      181 ttatctgctt tctctggttc gtttgcttcg cacaaacgac gtaacagtgc attttgacgt
      241 ttttgctgat ccagcaacgc ctcaagcagt tcaatctgtt cgttagtccg tgaactggca
      301 cgattgataa aaaaccacaa gatgagcccg ataagaagaa ccaccaccga tacaaccaaa
      361 gacgcaatgt tcatcacgcc tgaatttaca acttcgttca tttcaccacc tctgagtaga
      421 ggcgctattc taccactgct ggagaggaag aaaatctagt gctgaaaaaa tgatatcacc
      481 acgggataaa ctggttaatg gcacaaattc cgctgaaaaa ttgtacatcc tgatcgcaca
      541 tcatgttgaa tacctgcgcc caaagcagca agcaagccaa caccacgaca accagaacga
      601 cccatcgaaa ctttttcact ccaatctccg tttcacctac cttatgtcat taaactagca
      661 tgcgttagtt aaacagcgcc taactatgtc gatattcgtg ctttttcgga atgagtcgct
      721 tgcttcagcg catattgccg ctacgattaa gcgaacataa aaagagaaga ggttgtaatg
      781 cgattcatca ttcgcacagt tatgctgata gcactggtat ggataggatt attactcagc
      841 ggatatggcg ttttgattgg aagcaaagag aatgccgcag gattaggttt gcaatgtacc
      901 tatctgactg ccagaggcac cagcacggta caatacttgc acactaaaag tggttttttg
      961 gggataacag attgcccgct gttacgcaaa agcaatatcg tggtcgataa tggttaaggg
     1021 caataaataa ccagattctc actcctgagt aaaatactct tatagcaagc gcgtttaata
     1081 taacgccacc ttcaacttta tttttctcat gctaaataaa gaacctgtct gtttgatatt
     1141 ccgacaggtt cttactctca tcagaacgga tagtcgtgat aacccatttg ggcagaaatt
     1201 ttgcgcgctg cggtatgcaa cattgcgaca tattcctgta aacgctcttc agagaaacgc
     1261 aacgtcggga aggagatgct caaaccggca atgaccacgc caaagcgatc aaataccggt
     1321 accgcaatgc atcgcagccc ttcttcctgc tcttcattat cttcgccata cccctgctcg
     1381 cgcacctggt ccagaacggg taataacgct tctgtactgg tgatggtccg ctcggtactg
     1441 cgtttatact ccacgccctc aagaatttgc ttcacttcat cgcgatcgcg ccatgccagc
     1501 agtaccttac caatcgcggt gctgtacagc ggattacgac gcccaatccg tgaatacatg
     1561 cgcaaattgt acatagagtc aattttgtga atgtaaacaa tactgtcttc gtccagtgcg
     1621 ccgaggtgga tagtttcttt ggtcaggcgg gagagctcac gcatctggat atctgcgcta
     1681 cgaattaaat cgacgttttg taacgcgcga gcgcccagtt caaacaattt cagggtcagg
     1741 gaatatttct ccgactcccc ttcctgcgcc acataaccta aggttttcat ggtctgtaaa
     1801 aagcgataaa cggtgctttt tgacatcatg acgcgctgcg acagctcggt tatccctatt
     1861 tcgcgctctt cacccagcgc ctgcaaaatg ccaaaaactt ttagcacgga agatacagaa
     1921 tcaggctgtt tatccagatc tgcgttagcc atttatcacc tcattgcgag tgttttataa
     1981 aaatcagaac tgttttttat tataatttcg caccagggtg gtcgcaatcc atcttttgcc
     2041 ggttagttac aattctgcga catccaccgt gaatatcagt gctagaatca tacccctgtt
     2101 gattattcac caaagatata aaattcctat gccaaaagtt caggccgacg gcctgccatt
     2161 gccccagcga tacggtgcga tattaaccat tgtgattggt atttcgatgg ccgtccttga
     2221 cggcgcaatc gccaacgtcg ccctgccaac aatcgccacg gaccttcatg ccacgccagc
     2281 cagttccatc tgggtagtga acgcctatca aatcgccatt gtcatctccc tgctctcgtt
     2341 ttcgtttctg ggcgatatgt ttggctatcg acgtatttat aaatgcggtc tggtcgtttt
     2401 tctgttgtct tcactgttct gcgccctttc tgattcgctg caaatgctca cccttgcgcg
     2461 tgtcatacaa ggtttcggcg gtgcagcgtt gatgagcgtt aataccgcac ttatccgcct
     2521 gatctatcca caacgttttc tgggtagagg gatgggcata aactcgttta ttgttgccgt
     2581 ctcttctgct gccgggccga caattgctgc agcaatcctc tccatcgcat cctggaaatg
     2641 gttattttta atcaacgtac cgttaggtat tatcgccctg cttctggcga tgcgttttct
     2701 gccacccaat ggttctcgcg ccagtaaacc ccgtttcgac ctgcccagcg ccgtgatgaa
     2761 cgcgttaacc ttcggcctgc ttatcactgc gttgagtggt ttcgctcagg ggcaatcgct
     2821 gacgttaatt gctgcggaac tggtggtaat ggttgttgtt ggtattttct ttattcgccg
     2881 ccagctttct cttcccgtac cgctgctacc ggtggattta ctgcgtatcc cgctgttttc
     2941 actttctatt tgcacatctg tttgctcttt ctgcgcacaa atgctggcaa tggtttccct
     3001 gcccttttac ctgcaaaccg tgctcgggcg tagtgaagtc gaaacaggtt tacttctgac
     3061 accgtggccg ttagcaacga tggtgatggc tccgctggca ggctatttga ttgaacgcgt
     3121 acatgcagga ttgctggggg ctttagggtt gttcatcatg gctgcggggc ttttttccct
     3181 ggttctgctg cccgcgtcac ctgcggatat caatattatc tggccgatga tcttatgtgg
     3241 tgctggattt ggcttattcc agtcacccaa taaccacacc attattacct ccgcgcctcg
     3301 cgaacgtagc ggtggagcca gtggcatgtt aggaacggct cgtctactgg gtcagagtag
     3361 cggcgcggcg ctggtggcgc tgatgctaaa tcagtttgga gataatggta cacacgtctc
     3421 gctgatggct gcggctattc tggcagtgat tgctgcctgt gtcagtggtt tacgtatcac
     3481 tcagccacga tccagggcat aaaaaaagcg cgtcgatcag gacgcgcttt ttagtattta
     3541 cttcatatta cttcaggtat tcacccgtac gcagagcttc aattcgttta tccagcggcg
     3601 ggtgggtcat gaacaactca ctgagcgatt tcgacttacc gttaatgcag agagccatca
     3661 tgctggttgc ttcttgcggt tcatagctgg ttttcaggcg ctgcagcgcg gcaatcattt
     3721 tctcgcgacc aaccagtttt gccgaaccgg catcagcatg gaattcacga tgacgcgaga
     3781 accacatggt gataatgctc gccagaatac caaacaccag ttccagaacc gttgcaaccg
     3841 caaagtagat cagcgggttg ccgttgctct cttcaccttc atcacgattt ccgcccataa
     3901 aacccgcggc aagctgcgcc agaatacggg aaataaagat aacgaaggtg ttcaccacgc
     3961 cctgaatcag cgtcatggtg accatatcac cattggcgat gtggctgatt tcgtgagcaa
     4021 ttaccgcctc ggcttcatcc gggctcatgt tctgcagcaa accggtgctg acagcaacca
     4081 gagaggcatc acggcgcgca ccggttgcaa aagcgttgat gtccggcgca tggtagatag
     4141 ccacttgcgg catagcgatc cccgcctgac gagcctgggt tgctacagta ttgaccagcc
     4201 aacgttccct ttcgttacgc ggttgctcga tcacttcccc gccaacagat cgtaatgcca
     4261 tccatttgga catcagaagc gaaacgaagg aaccaccaaa accgaacagc aaggccatga
     4321 tcatcagccc ctgaacgctg ctcgactgta tccctgtcag gctcagtacc agcccgaaaa
     4381 cgaccattac ggccaggttc gttagcagga agagcgcgat tcgcatcata attttctttt
     4441 tacctcagtt taacaaaacg caatatgcga tacccacatc gtatgggtta cgcgactatt
     4501 ttcaagtctg gatagtgcgt aagtcaccag aaagacacaa ctttacattt tgtagcatct
     4561 gatttacggc atcttgtcgc tgttaaaaaa tcaggcacaa tttcttgtgc ctgattgata
     4621 ttacttgacg ggagcgggtt gttccgcggg tctggctttt tcaagcttcg ccagatcgag
     4681 tgcgatattc accgtctcat ccagataagg atccggctcc tggtaatctt tcggtagatc
     4741 atccagtttc ttcaactccg gtttaccttc gcgtttaaag cgttcgttca aacgcgccag
     4801 acgcgtcgca tcatcttcat tattctcttt ctcacgcaca gcgtaattca gagaaacgat
     4861 attgcgcttg tccttcatag cgttgaagcg cgcgatatcc ttcatgatgt tctggaactc
     4921 aggatctttc gcgatacgcg cattatgttc cttcagcagc tccggttcaa aggccgttaa
     4981 atctcctgat ttcacataag tcgcggcatc aatgctatcc cacggcagcg cgttatcttc
     5041 gaatttctca cccgtttccg tttcttcatt acccgtcggc atgatgatgt ctggcgttac
     5101 gcctttacgt tgcgtactgc cgccgttaac gcgatagaat ttctggatcg tgtactgcac
     5161 agaacccagc gctggccatt caggacgtaa catctgatcg taaatacggt tcaatgaacg
     5221 gtattgctga acggtgcctt taccaaacgt cggttcaccc acaaccagcg cacgaccgta
     5281 atcctgcatt gccgcggcaa agatttctga agccgaagca ctgaagcggt caaccagcac
     5341 caccagcggg cctttataga aaacctgtcc gtcggtatcg ctatcttcac gaaccttgcc
     5401 gttgttatcg cggacctgaa caatgggacc cgcaggaata aacagaccgg agagcgatac
     5461 ggcttcagtt aacgccccac cgccattgct acgcaggtcg atgatgacgc tgctgacatt
     5521 ctgtttttcc agtttctgca gttgcacttt gacatcgtct gtcaaaccca catagaagcc
     5581 cggaatatcc agcacgccga ctttctcttt accgacggtc ttcaccgaca ttttaaccgc
     5641 gcggtcttcg agacgaatac gttcacgggt caacgttaca gtacgggtct tggtcccttt
     5701 accagcaggt aaaatttcca gacgaacttt actgcccttc ggccctttaa ttaaggcaac
     5761 cacatcatca agacgccagc caatcacgtc aaccatcggc ttgcctgttt gaccaacacc
     5821 gacaattttg tcaccaacgc tgatagcttt actcttcgct gccggaccac ctgccaccat
     5881 cgaattgata acggtgtagt catcatccat ttgcagcact gcgccaatac cttccagcga
     5941 caaactcatt tcagtgttga actgttcggt attacgcggg gaaagatagt tggtatgcgg
     6001 gtcgatttca cgcgcaaacg ccgtcattgc cagcgagaaa acatcttcgc tgttggtttg
     6061 cgccagacga cgaatggcaa atttgtagcg gcgagtcagg gtttcacgaa tttctttatc
     6121 cgtttttcct gtcagcttca ggcttaactc gtcgaatttg actttactgt cccacagcgc
     6181 gttcaactca gcctcgtttt tcggccaggg cgctttgctg cggtcaaggt tataagtgtc
     6241 gttgccggtg aaatccatcg gcttttccag taccgacaaa gcgtactggt aacgctcaaa
     6301 acggcgcttt tgcgccagat tgtagagatc gtagaaaacg tcgagtttgc ctgaacgcag
     6361 ttcatcgcct aactcggttt tctttttcgc gaactgttca acatcgcttg ccagcagcac
     6421 gttgtggctg taatcgagca gattcaggta gcggtcaaag attttagccg aaaatgcctg
     6481 atcgagttcg aactggcgat aatgagaacg ggtgaagcgc gacgttacgc gctcacttac
     6541 cgtcgcatgc tgcgtctctt cctttaatac cggaatttga tcagcacgcg tgatatcttc
     6601 tacagcgaag gtctggcctg ctattgcaag caggccagct aacgcggtaa gcctaaaaaa
     6661 catgttcatg cctggcccgg cctccgtttc agaacaccag gtgttctgcg cgcacaatca
     6721 aagacatacc cgaattcagc tggacgcgga cgccgtcttt ggtgatttct aatacggtgg
     6781 catccatcgc gttttgaccc gctttcacct tcagggcttg tccgacagtc agagctgaaa
     6841 tgtcagaaac cggggtgtgc tgttcttcgc gaggtgcttt tactgttttt ggcgctttct
     6901 ctaccggctt ttgcgcacga ggtttacgtt cagcgccttc tttgcggcgt ggcgtagtcg
     6961 gacgtggctt gcgttcgcgg cgcggtgcgt cttctttctc accagcagtt gcggcagctt
     7021 cgcgtttttt cgcttgctgt tcagcacgct gtgcctgaac acgcgctttc gcttcttcaa
     7081 gctgcttgcg agcatgctct acatgttgct cgtccagctc accgcatggg ttgccgtcaa
     7141 gatcgacacg cgttgcgccg ggtttaacac cgtaaagata acgccagctc gaagtgtaga
     7201 gacgtaaagc ggatcgcaat tgcgttttgc tcaggttcat ttccccagca acacgatcga
     7261 ccaaatcctg aaaaataccg attttcagcg gacgcgcttc accttccgca ctgaaacagt
     7321 ggggaaaacg ttcggccaga aacgcgatta cttctttact gctattcaac ttaggttgat
     7381 tttccatgaa atttcctgat tacaacggac gtagccaaca agcgcaggca tgaacaggcg
     7441 tcattataat gacgctatca gtaaatgcta cgttatccgt tgattatcct gcgacgctcg
     7501 caaagaattt tttgtaatcc gtcgttgcaa gcactttttc aagcagtgcc acaagctgac
     7561 gtaagccttg ctcgtcctcg tctgtaaagc gaccgaagac ggtactatcg atgtcgagaa
     7621 caccaataat ctgatttttc accaccagcg gcagaacaat ttcagaatta ctcgccgcat
     7681 cacaggcaat atgcccgtca aacacatgaa catcctcgat acgctgcact tgattgcggg
     7741 caaccgcagt gccgcacacg ccgcgcccga cgggtatccg gacacaggca attttgccct
     7801 gaaatggtcc gagtaccagt gtatcgtcct caagcaaata aaaacctgcc cagtttatgt
     7861 cagtgagacg ctcatataac aacgcactgg tgttcgcaag cgttgccaga aaactggttt
     7921 ctcccgccat cagcgcgtta aagtcgcgat ttaaatccgc gtaaaattct gttttgttca
     7981 ttatataatc acttggttgt cttacctgga tctgccagcc tattaaaata agcattaaat
     8041 gcgttaatgc tcaagatcat tcccatcatg ggttaagatt aatgttaatt cttattacat
     8101 ttggcacgtc atggctctta acacaccaca aattacgccg acaaaaaaga taacagtgag
     8161 ggcaatcggc gaggaactgc cgcgtggtga ttaccaacgt tgcccgcaat gtgacatgct
     8221 gtttagcctg cccgagataa attctcatca aagtgcctat tgtccgcgct gtcaggcaaa
     8281 aattcgtgac gggcgcgact ggtcgctaac gcgcctggcg gcaatggcct tcaccatgct
     8341 gttgcttatg ccgtttgcct ggggcgaacc gctgttgcat atctggctgt taggcattcg
     8401 tattgacgcc aacgttatgc aaggcatctg gcaaatgacc aaacagggcg atgcgataac
     8461 ggggtcgatg gtctttttct gcgttattgg tgccccgctc attctggtga cctccatagc
     8521 ttatttatgg tttggtaacc gactgggaat gaatttacgt ccggtactgc tgatgcttga
     8581 gcgacttaaa gagtgggtaa tgctcgatat ctacctggtc ggcattggcg ttgcttctat
     8641 aaaggtacag gattatgccc atatccaggc tggtgtcggc ttgttctctt ttgtggcgtt
     8701 ggtgatttta acgacggtga cgttgtcaca tcttaatgtc gaagaactgt gggagcgatt
     8761 ttatccgcag cgccccgcta cgcgtaggga cgagaaactt cgtgtctgtc ttgggtgcca
     8821 ttttaccggc tatccagatc agcgtggtcg ctgcccgcgt tgccatatcc cgctacgcct
     8881 gcgtcgccgt catagtctgc aaaaatgctg ggcggcgctg ttagcgtcaa tcgttttatt
     8941 gttacctgcc aacctgttgc ctatttctat catttatctg aacggaggac ggcaggaaga
     9001 tacaattctt tccggaatta tgtcgctggc aagtagcaac attgcggttg caggaatcgt
     9061 gtttatcgcc agtattctgg taccgtttac taaagtgatc gtcatgttca ctttactgtt
     9121 gagcattcat tttaaatgcc agcaaggttt acgcacacgc attctgttac tgcggatggt
     9181 gacctggatt ggtcgctggt cgatgctcga cctgtttgtc atatctttaa ccatgtcgct
     9241 gattaatcgc gatcagatcc tcgcttttac tatgggaccg gctgcgtttt atttcggcgc
     9301 agcggtaatt ttgactattc ttgctgtgga atggctggac agccgcttac tttgggatgc
     9361 acatgagtca ggaaacgccc gcttcgacga ctgaagcgca gattaaaaat aaacgccgta
     9421 tctcaccttt ctggctgctg ccgttcatcg cgctaatgat tgccagttgg ctgatttggg
     9481 acagttatca ggaccggggt aataccgtca ccatcgactt tatgtcggcg gatggtattg
     9541 ttccaggccg tacgcctgtt cgttatcagg gcgttgaagt cggaacagtg caggatatca
     9601 gcctcagcga cgatcttcgt aagattgaag tcaaggtcag catcaagtcc gatatgaaag
     9661 atgcgctgcg cgaagagact cagttctggc tggtgacgcc aaaagcatcg ttggcaggtg
     9721 tctccgggct ggacgccctc gtcggtggga actatatcgg catgatgccg ggtaaaggta
     9781 aagagcagga tcactttgtc gcactcgata cccaaccgaa atatcggctg gacaatggcg
     9841 atctgatgat ccacctgcaa gcccccgatc tcggttcgct gaacagcggt tcattggtct
     9901 atttccgcaa gatcccggtg ggaaaagtct acgactatgc catcaatccc aacaagcaag
     9961 gcgtggtgat tgatgtcctg atcgagcggc gttttaccga tctggtgaaa aaaggtagcc
    10021 gtttctggaa cgtttccggc gttgatgcca acgtcagtat cagtggcgcg aaggtgaaac
    10081 tggaaagcct ggcggcactg gttaacggtg cgattgcctt cgattcacca gaagagtcga
    10141 aacctgccga ggcggaagat acctttggtc tgtatgaaga tctggcccac agccagcgtg
    10201 gcgtaataat aaaactggaa ctgccgagtg gggccggatt aaccgccgac tcgacgccgt
    10261 taatgtatca ggggctggaa gtcggacagc tgactaaact ggatttaaat cctggtggta
    10321 aagtcacagg ggaaatgacc gttgatccca gcgtcgttac cctgcttcgt gaaaataccc
    10381 gcatcgaatt acgcaacccg aaattatccc ttagcgatgc taatctcagc gccctgctga
    10441 ccggcaaaac cttcgagctg gtgcccggcg atggcgagcc acgcaaagag ttcgttgttg
    10501 tgccaggcga aaaagcactg ctgcatgaac ctgatgttct gacgctgacc ctgaccgcgc
    10561 cggaaagtta cggtattgat gcgggtcagc cgctcattct tcacggcgtg caggtaggcc
    10621 aggttatcga tcgtaaactc accagcaaag gcgtcacctt taccgtcgcc atcgagcctc
    10681 agcatcgcga actggtaaaa ggcgatagca aatttgtcgt caacagccgt gtcgatgtga
    10741 aggtggggct ggatggcgtt gagtttctcg gtgccagcgc ctcagaatgg atcaatggcg
    10801 ggatacgtat tctgccgggc gataaaggtg agatgaaagc cagctatcca ctgtatgcca
    10861 atttggaaaa agcgctggag aacagcctta gcgatttacc caccacaacc gtgagtttga
    10921 gtgcagagac gctgccggat gtgcaggcag gatcggtagt gctgtaccgt aaatttgaag
    10981 ttggtgaagt gattaccgtg cgtccgcgag ctaacgcgtt tgatatcgat ctgcatatta
    11041 agccggagta tcgcaacctt ctgaccagca atagcgtgtt ctgggcagaa ggcggggcga
    11101 aagttcagct gaatggtagt ggtctgaccg tacaggcatc cccgctctcc agagcattaa
    11161 agggagccat tagcttcgac aacctcagcg gtgccagcgc cagtcagcgt aaaggcgata
    11221 agcgtattct gtatgcttcc gaaacagcgg cccgtgcggt tggcgggcag attacgcttc
    11281 acgctttcga tgccggaaaa ctggcggtcg ggatgccaat tcgctatctc ggtattgata
    11341 tcgggcaaat ccagacgctg gatctgatta ccgcacgcaa tgaagtacag gcaaaggcgg
    11401 tactttaccc ggaatatgtc cagacctttg ctcgcggtgg tacgcgcttc tcagtggtca
    11461 caccgcaaat ttcggcagct ggcgttgagc atcttgatac tatcctccag ccgtatatca
    11521 acgtcgaacc aggccggggc aatcctcgcc gcgactttga attacaagag gccaccatta
    11581 ctgattcgcg ttacctggat ggcttaagca ttattgttga agcgccggaa gccggttcgt
    11641 taggcatcgg tacgcctgtg ctgttccgtg gtctggaagt cggtacggtt acaggaatga
    11701 cgctggggac attgtcagat cgcgtgatga ttgcgatgcg catcagtaaa cgctatcaac
    11761 acctggtgcg taacaattcc gtcttctggt tggcatcggg ttacagtctg gactttggtc
    11821 tgacgggcgg cgtagtgaaa accggcacct ttaaccagtt tatccgtggc ggcatcgcct
    11881 tcgccacgcc tccgggtacg ccactggcac cgaaagccca ggaaggcaaa cacttcctgt
    11941 tgcaggaaag tgaaccgaaa gagtggcgtg aatggggaac tgcgcttccc aaataatgcc
    12001 cactgctccg gcgtgcctgc gccggagcgt ttatgctaaa ctgcgcgcct gtttttttgc
    12061 cagtggtaca tgctcgtggc ccaacacacc gtttatttcc cggacgcctt tctgacacaa
    12121 atgcgcgaag cgatgccttc gacgctctca tttgatgatt ttcttgccgc ctgtcagcgc
    12181 ccgttgcgcc gcagcattcg cgttaatacg ctgaaaatct ccgttgctga tttcctgcaa
    12241 ttaaccgctc cttatggctg gacgcttacg ccaattccgt ggtgtgaaga aggtttctgg
    12301 attgaacgcg acaatgaaga tgcattgcca ttgggtagta ccgccgagca tttaagtggc
    12361 ctgttttata ttcaggaagc cagttcaatg ttgcctgttg ccgccttgtt tgctgacggt
    12421 aatgcaccac agcgggtgat ggatgtcgct gccgcgcctg gctccaaaac gacgcaaatt
    12481 tccgcgcgga tgaataacga aggggcaatc cttgccaatg agttttccgc cagtcgggta
    12541 aaagtgttac atgccaatat cagccgctgt ggtatcagta atgttgcgct cacacatttt
    12601 gatggccgcg tgtttggtgc ggcagtgcca gaaatgttcg atgccatttt gctggacgct
    12661 ccctgctctg gcgaaggcgt ggtgcgtaaa gatcccgatg cgctaaaaaa ctggtcacca
    12721 gaaagcaatc aggaaatcgc agctacacaa cgggagctta tcgacagcgc ctttcatgca
    12781 ttacgtcctg gtggtacgct ggtttactcg acctgtacct taaaccagga agaaaacgaa
    12841 gccgtttgcc tgtggctgaa agagacttac cccgacgcag tagagttttt accacttggc
    12901 gatctcttcc ctggtgcaaa caaagcgctg accgaagaag gctttttgca tgttttccca
    12961 caaatttacg actgcgaagg cttcttcgtt gctcgtctgc gtaaaactca ggcgattccc
    13021 gccttacccg cccccaaata caaagtcggt aattttccgt tcagcccggt gaaagatcgc
    13081 gaagctggac aaattcgtca ggcggctaca ggtgttggct taaactggga tgaaaacctg
    13141 cgcctctggc agcgtgacaa agaactgtgg ttgttcccgg tgggcattga agccctgatc
    13201 ggtaaagtcc gattttctcg gttggggatt aaacttgccg agacgcacaa caaaggttat
    13261 cgctggcagc atgaagcggt tattgctctt gcctcacccg ataatatgaa tgcattcgag
    13321 ctgacaccgc aggaagcgga ggagtggtat cgcgggcgcg atgtttaccc gcaagccgcg
    13381 ccagtggcgg atgatgtatt ggttactttc cagcatcaac cgattggttt agccaaacgg
    13441 attggttcgc gattgaaaaa cagctatccg cgtgaactgg tgcgcgatgg gaaacttttt
    13501 accggtaacg cctgacagcg cacaaaaaaa gcgcactttt tgactggcac attcggctgc
    13561 ctcaactagg ctgaaaaatg gtgcgatcgg actggtcgta ccacaatcgg cagctaaatg
    13621 gagagcacga agatgaaaac cagtgtgcgc ataggcgctt ttgaaatcga cgacggcgaa
    13681 ttacacggtg aatcgccagg tgatcgaacg ttaaccattc cttgtaaatc tgaccccgat
    13741 ttatgtatgc aactggatgc ctgggatgct gaaaccagta tccctgccct gctaaatggc
    13801 gaacactctg tcctttaccg tacccgttac gatcaacaat ctgatgcctg gattatgcgt
    13861 cttgcctgat ccaaaaagaa cccgtcggca tggcgggtta tttgtcctgg ttattccccc
    13921 gttgtaaaat ctctcctaaa cttaacggta cggcaccaca cttcggggat gaaatgttcg
    13981 cgctggtact ttttgtttgc tacctggatg gcggttgtga agatattgtt gtggatgtct
    14041 acaacacgga acagcagtgt ctttattcta tgagcgatca acggatccgc cagggcggtt
    14101 gttttccgat tgaggatttt atagatggtt tctggcgacc tgcacaggag tacggtgatt
    14161 tttaattatt gcaattgcac aagagtcagt tcgcccccaa agacagcacc ggtatcaata
    14221 taatgcaggt tgccaatatc cacgcgatgt cgcaacggtg tatgaccaaa ccagaaatga
    14281 tcagcacctg taattccctg ccctttttgg cgttcaccta atcgcgagcg gctccacaag
    14341 acctgatgca aatcaacgtc cttttgccat tcataaacat catctggata atcggcatga
    14401 gcaataacat gcttgccggt gcgactgtgt acttcaagaa taaagggcaa atgctgacat
    14461 ttttccagcg ccgttttcgc ttgtttctgt tgattatctg ccagcgcaat aaaccagtcg
    14521 ccgccattca tcaaccacaa agacatctgc tgggatgcca gcgcatccat cgccatctgt
    14581 tcatgattgc ctcttaccgc acaaacccaa tgttgttcca gtaactgcag acaacgtaaa
    14641 ctttgcggcc cacgatcgat aacgtctccc actgagataa gtaaatctcg ccacggatca
    14701 aaacgacaat gccataattt gcggcgcaac tgctcaagac aaccgtgtat atcgccagaa
    14761 agccagatat gtcgccattg atgacccgca attctctgat aaacgggcgc aggctgtttc
    14821 atcaatattt tcctcccgcg ctaaagatca cataatctta acaagaatgt taaaaaacgc
    14881 tggactcaga cagtagagtg tgtgttatgg ttgactataa agtcagcgaa ggaaatgctt
    14941 ctggctttta acagataaaa agagaccgaa cacgattcct gtattcggtc cagggaaatg
    15001 gctcttggga gagagccgtg cgctaaaagt tggcattaat gcaggcttag ttgccttgcc
    15061 ctttaagaat agatgacgac gccaggtttt ccagtttgcg tgcaaaatgg tcaataaaaa
    15121 gcgtggtggt catcagctga aatgttaaaa accgcccgtt ctggtgaaag aactgaggcg
    15181 gtttttttat tggaaatcaa aaggctattt taggtaatta acagagtttt tcagctcgtt
    15241 ctataaacgg tgccagactc attttttcgc cgggattgtt aggatcatca atctgaatca
    15301 ccgaaatggg ttgggcattg gtcttcccac tggcaacttc cttttgtgcg atatcgttta
    15361 aaggatactg cacgagggta ctcggattaa taacatacaa agcattaccc ggtcggcaag
    15421 tcagcatcac ctcttcgcga ttaaacgccc atttgtcttt acccacttca aaacgactga
    15481 cggtaatcac ctgcggtgca gccagcgccg ctgcagaact ggtgagtaac agaaacgcca
    15541 gaatactttt tttcatcatt ttcgtaatcc atcaaaaagg ttcgagagtc gcaagcaggc
    15601 tgatgatcac cagcactacc gcacctatcg cccattcgag tttagtcatc cacacaaacc
    15661 agggtgccgc acgatcttca tcctgcctca tgcgcggtac aagaacataa cgattagcca
    15721 gcgcaatgac caccataatc atcaccagga tggctttgag caataagagt tggccccagt
    15781 aagtcgtaag cgtgggggga aatccggtaa tcaacaatgc attaagcacg ccgcttgcca
    15841 gtacgccgat caccgcaaaa tgcccgcacc aggaaaaacg catcagcgcc tgaatagcct
    15901 ggtgtcgcca acggcctttg atgagttgca tacaccagag caccggcagt aatcccccaa
    15961 accacgccgc cgcacaaatc aggtgaatcg cgtgattagt ctgatggatt ttcgctgtta
    16021 ccccttcatt cagcgtcgca tgccccactc ccgccagcag aataaattgc gcggtagtga
    16081 tcataaacag caaacgtggc atattccgcg gttgcataag ggcgacgatc aacgttacga
    16141 gggcgagaac aatttgccat aaccagatgc caccaaactg cgtttgcaaa acagcctgcc
    16201 aaatgtttgg cgaaaataca tctgtccatc ccgttcccat caacccgccc tgaacggcga
    16261 gcattgcagt ggcactgatc aaactccaga cggcagcgtg ctgttgtaaa cgcagaaaac
    16321 gcttcgccag caagcgacga atcgtcaagg gggccagcca ggcaccgtac attgcgaagc
    16381 caaaaaccag catcagcgag gtgaaatgga taaatcgcag cgcgatccag gtaaacgcca
    16441 gcatgattta tttcacgcta aaggtgtagt gtcctttcgt tttatgcccg tccaccgaaa
    16501 caacatgcca gtcaacggtg taggttccgg gtttcagcga atcggccagt ggaacaatca
    16561 gttgcttttg gtcctgctca tttcgcttcg ccggtaatgt tttaatattt tcgttttttg
    16621 gccccgtgat ttttgcacca ctgaatcctg tttcaacacc ttccgagaag tttaaagtga
    16681 ttgcctgcgg tgcagctgtc acttgcgcgt ttgccgcagg atactgatgc gttaaatgcg
    16741 catgtgccca gacggaaggt gtcaccaacg aagtggtcag gattgccagc gcgtagcgaa
    16801 gggagcgtgc agttgaagcc atattatcta ttcctttttg taataacttt tttacagagc
    16861 ataaccttgt ctaatgtctg agtcgaggat catcaattcc ggcttgccat cctggctcac
    16921 tcttagtaac ttttgcccgc gaatgatgag gagattaaga atgctgaaga atctggctaa
    16981 actggatcaa acagaaatgg ataaagtgaa tgtcgatttg gcggcggccg gggtggcatt
    17041 taaagaacgc tacaatatgc cggtgatcgc tgaagcggtt gaacgtgaac agcctgaaca
    17101 tttgcgcagc tggtttcgcg agcggcttat tgcccaccgt ttggcttcgg tcaatctgtc
    17161 acgtttacct tacgagccca aacttaaata aaacttatac agagttacac tttcttacat
    17221 aacgcctgct aaattatgag tattttctaa accgcactca taatttgcag tcattttgaa
    17281 aaggaagtca ttatgtcgtt ctggaaagtt gcagcagcgc aatatgagcc tcgtaaaacc
    17341 tcactcaccg aacaggtagc tcatcatctg gagtttgtga gggccgccgc caggcaacaa
    17401 tgtcagctgt tagtttttcc atcgctttct ttactggggt gtgattattc gcgacgtgcc
    17461 cttcctgccc cacccgatct ctcactgtta gacccgcttt gttatgccgc aacgacctgg
    17521 cgaatgacca tcattgccgg ccttcccgtt gaatataacg atcgctttat tcgtggaatt
    17581 gcggtgttcg caccgtggcg aaaaacgcct gggatctacc atcagagtca tggtgcatgt
    17641 ctgggccgtc gttccagaac catcacggtg gtcgatgaac aaccgcaagg tatggatatg
    17701 gacccgacct gttcactgtt tactacaggg caatgtctgg gagaacccga cctgctggcg
    17761 tcggcccgtc gcttacaatt tttttcacat cagtactcga ttgccgtgct gatggcaaat
    17821 gcccgtggta acagtgcact atgggatgaa tatggtcgtc tcatcgttcg cgccgatcgt
    17881 ggttcattat tgttagtcgg tcagcgttca tcacagggtt ggcaaggcga tatcattcca
    17941 ttacgctagg ctttttcggc ctggagcatg ccatgttgcg cattatcgat acagaaacct
    18001 gcggtttgca gggagggatc gttgagattg cctctgttga tgtcattgac ggaaaaatcg
    18061 tcaaccccat gagccacctg gtgcgccccg atcgtcctat tagtccacaa gcgatggcga
    18121 ttcatcgcat caccgaagcc atggtcgccg ataaaccgtg gattgaagat gtgatcccac
    18181 actattacgg tagtgaatgg tatgtcgcgc ataacgccag ctttgaccgc cgcgtactgc
    18241 ctgagatgcc cggtgagtgg atttgcacta tgaaactggc ccgtcgtttg tggcctggga
    18301 tcaagtacag caatatggcg ttatataaaa cacgcaagct caatgtacag acgccgccgg
    18361 gcctgcatca tcaccgcgcg ttgtatgact gttatatcac cgccgcgttg cttatcgata
    18421 ttatgaacac ctccggctgg acggcagaac agatggccga tatcaccgga cgtccgtcgt
    18481 tgatgacgac cttcaccttt ggcaaatacc gtggcaaagc ggtttccgac gttgccgaac
    18541 gcgatccggg ctatctgcgc tggttattta ataacctgga cagcatgagc ccggagctgc
    18601 gtttaacact gaaacattat ctggaaaata cttagtccgc aggcgtagcg ggtaatgttc
    18661 cctgcgccag cgcgaccaga aaagcatatt ccatcgctac gccttcgtac gatttaaagc
    18721 gaccagattt accgccatgg cctgagtcca tgtcggtaca gagcaataaa agatggtcat
    18781 cggttttcag ctcgcgcaat ttagcgaccc attttgccgg ttcccaatat tgcacctgag
    18841 aatcgtgcaa accggtcgtt accagtaaat gcggataagc ctgtgcggtg acgttgtcat
    18901 acgggctgta gcttttcatg tactcgtaat attgcggatc ctgcgggtta ccccactctt
    18961 caaactcacc agtggtaaga ggaattgatt catcaagcat cgttgttaca acatcaacaa
    19021 acggtacctg ggcgataacg ccgtggaata attccgggcg ttgattaatt gcaacgccca
    19081 tcaacatgcc ccccgcactc ccgcccatcg cataacaaag cgaaggagag ccatagccca
    19141 gttttaacaa tgcatcgcag gcatcaagat aatcattaaa cgtatttttc ttcttcagaa
    19201 attttccgtc ttcgtaccat tgttgcccca gctcaccacc gccgcgaaca tggacaatgg
    19261 cgtagacaaa gccacgatct aacaaactca agcggctaaa actgaaatcg gcatcaatac
    19321 ttgcgccgta agaaccatag ccatacacca gcaacgggtt gtgtcctttg cgaaaatgtt
    19381 tgcgatggta gaccaacgaa accggaactt cgacgccatc acgggcgact atccacaggt
    19441 gttcactgcg gtaattcgcc gcataaaaac caggaacttc cgtttgtttt aatacacgac
    19501 gctcaccggt atccatatcc agttcaaaca aagtgtctgg tgtagtcatg gaagaataac
    19561 cataacgcaa tcgcgcggtt tcaggttctg gattgtaggc aatccaggtc acataggccg
    19621 gatcatcaaa ggcaatacca atgacttccc gggtcttgcg gttaatttgg cgcaaactgg
    19681 ttaacccgcg ctgacgctct tcaaccacca gccagtcggt aaacagcgta aacccttcca
    19741 gcatgatgtt ttcgcgtggc ggaattaact cttcccactg ttgctcatca cgcatacggg
    19801 tacggtataa gccaaagttt ttgccgtggc ggttggaacg cagataaaaa cgatgctggt
    19861 agtgatcaag gctgtattcg tgatctttgc ggcgcggcag aaaaacaaac ggctcggcat
    19921 cggccatttc cgcgtccagc aggcgaactt cactggtggt ggcgctggcc aaatgaatga
    19981 ctacatagtg cttcgaggtc gttttatgca ggctgacgta ataggtatcg tctttttctt
    20041 cgtagatcag tttatcttgc gatgctggcg taccgatggc gtgacgccag acctgataag
    20101 gcagcagcgt caccggatgc ttgcgaacat agtagaaaat ccaggagtca tttgcccaga
    20161 caaagctggg ttcaacgtta tccagcagtt ccgggtacca gttaccagtt tccagattac
    20221 gaaaacgaat gccgtactgg cgtcgggaaa gaaaatcttc tgccagcgcc ataatggtgt
    20281 tatcgggcgt aatcgccatt ccgcccatcg aataaaactc actatgagct gcgcgcttat
    20341 tggcatcgag caatgtttcc cactcatccc actcttcact gaatgccgat tgacgctggt
    20401 agatagcata ttcacagcct ggttcataaa tatgccgata gcggtagcca tttttgatgt
    20461 agggcgcaga aacttctcgt tgcggaatgc ggtcgatgat ttcctttaag atgcgatcct
    20521 gcaaggcttg ttgtgaggcc atcacccgat gaccgtaact attttcttgt tgcaggtagt
    20581 ccaggacttc tggctgagaa cgcgtatcgt cccgcagcca gtagtaatta tcgatgcgcg
    20641 tatcgccatg aagcgtcatg gcgtggggaa tgcgggcggc ttttggtagc atgttattgt
    20701 tctttctggt tgaaacatct tataagggtg gcaaaactca ccggggatgc aagcgaaaca
    20761 ggggagtcat tgcttagatg atgacaggta atggcgcgga tatcgaatgt tatgcagaca
    20821 gagaaaatca gcctgttcaa atggctgtgc gattctggat agcccgaaat agtcaacttc
    20881 aggctatcca gagagcggaa ttattccgcc aaagtgcgtt tttgctgttc gagatcgcgt
    20941 tcaatgccgt cacgaacatc ctgggggatt ttcagcgcgt cacccagtgc attcaggtaa
    21001 ctgcgttcca taaaatggtc aatatcaata gccgcgcaac tcaggaaata gatttccagc
    21061 gcctcttctt cattgcggac cccggtagcc aggcgttgtg gatccagcgg ttgttcgatt
    21121 gcctgctcaa tgagtacacg cccctgctct tccacgccgg ctccacgcaa ttgctggtcg
    21181 attgccgcac gttctttggc atcaatatga ccatcacttt tagcggcaaa gaccagcgca
    21241 aggatcaaac gtgctgtacg ctcatccagc ggcgtacttt gcgcgccaaa ctgcggttcg
    21301 tcctgatgcg ccgcgcgaat tttatctttg tatttattcc acagcaccgt acccgctacc
    21361 gctccgccgc caaccagtaa cgcgttggtg ccatatttcg taagaagttt acgtgctgat
    21421 ttatttgcga ccagcagccc agccagtccg cctaatgcgc ctggcactaa cagtttgacc
    21481 aatccctgat ccgcagacga ggaggtagaa gaactgcttt gcccaagcag ggattgcagt
    21541 tgatttaacc agttagccat atttgctcct caataaccat ttttagtgcc tgtagcatag
    21601 cggatgagga tgtcagaaaa tgtatatcga gacaaaagat gcgcaaataa gcggggcggt
    21661 aggccgttat tcaaagaaat tcgcgccagg taaggtattt actgtatatc aggtgataag
    21721 ggtattttag gtgaaagtag tttgtcgttt tgagtggcat tgtttgatgc tgattgcccg
    21781 atgcgacgct gttgcgtctt ctcaggccta cgattgtggt gcgttctgga gcggacaagg
    21841 cactcgcgcc gcatccgcca acagtcaatc gaattatcag aagccattaa cgccgctgat
    21901 attccgccat tcccgctttg cagtccacgc tgacctggta atgaatatcg gcacttttac
    21961 cacgcacggt tagcggtact gaccatttat catctttacc ctgaatgtcc tgcaaactga
    22021 cccaagccac gggatcggcc tgaccgacaa ttttttgatc atctgcccaa cgcgccacgc
    22081 gattttgttg ataatcacgt tttacgctcg cggcaattcc ggcagcatcc agaccttcac
    22141 actttgggaa agtgaccgac ttgctggttt cattattggc agcgaaaact gatgcgcagg
    22201 cagaaaccaa caacagccct aaaaacgccc ctcttttttt catgtttttc tccatagcac
    22261 aatgattcag gagaaagcat ggtacaaatt gtcaggagcg caagttgctt caggccgcgt
    22321 gtgaggcatc ttcctcttcg gattcagcac cgacgacctg tggggacggt aatttgccgg
    22381 ttttcagaat ggtgctcagc acatcttttt gttctgccag ccatagcgaa agggcttcac
    22441 gttgctcgtc ttccatttgc actggagaat ttgtcagcca ggtgtcaagc agatccgccg
    22501 tatcaagcat tttgtcataa gcatcggctt cctttttgct ggtaaacgac attttctctt
    22561 cgccctcacg aatgactacg tatttaactt caaccgccat ttgcagcctc tcataataac
    22621 tgtgatttta tacagtatat ttcttttcgg ttgagaaatc aacatcagca ataaagacac
    22681 acgcaaacgt tttcgtttat actgcgcgcg gaattaatca ggggatattc gttatgacgt
    22741 tattaggcac tgcgctgcgt ccggcagcaa ctcgcgtgat gttattaggc tccggtgaac
    22801 tgggtaaaga agtggcaatc gagtgtcagc gtctcggcgt agaggtgatt gccgtcgatc
    22861 gctatgccga cgcaccagcc atgcatgtcg cgcatcgctc ccatgtcatt aatatgcttg
    22921 atggtgatgc attacgccgt gtggttgaac tggaaaaacc acattatatc gtgccggaga
    22981 tcgaagctat tgccaccgat atgctgatcc aacttgaaga ggaaggactg aatgttgtcc
    23041 cctgcgctcg cgcaacgaaa ttaacgatga atcgcgaggg tatccgtcgc ctggcggcag
    23101 aagagctgca gctgcccact tccacttatc gttttgccga tagcgaaagc cttttccgcg
    23161 aggcggttgc tgacattggc tatccctgca ttgtaaaacc ggtgatgagc tcttccggca
    23221 aggggcagac gtttattcgt tctgcagagc aacttgctca ggcatggaag tacgctcagc
    23281 aaggcggtcg cgccggagcg ggccgcgtaa ttgttgaagg cgtcgttaag tttgacttcg
    23341 aaattaccct gctaaccgtc agcgcggtgg atggcgtcca tttctgtgca ccagtaggtc
    23401 atcgccagga agatggcgac taccgtgaat cctggcaacc acagcaaatg agcccgcttg
    23461 cccttgaacg tgcgcaggag attgcccgta aagtggtgct ggcactgggc ggttatgggt
    23521 tgtttggtgt cgagctattt gtctgtggtg atgaggtgat tttcagtgag gtctcccctc
    23581 gtccacatga taccgggatg gtgacgttaa tttctcaaga tctctcagag tttgccctgc
    23641 atgtacgtgc cttcctcgga cttccggttg gcgggatccg tcagtatggt cctgcagctt
    23701 ctgccgttat tctgccacaa ctgaccagtc agaatgtcac gtttgataat gtgcagaatg
    23761 ccgtaggcgc agatttgcag attcgtttat ttggtaagcc ggaaattgat ggcagccgtc
    23821 gtctgggggt ggcactggct actgcagaga gtgttgttga cgccattgaa cgcgcgaagc
    23881 acgccgccgg acaggtaaaa gtacagggtt aaacccggca aaaaaacgct acaaaaatgc
    23941 ccgatcctcg atcgggcatt ttgactttta cagcttagcg ccttctacag cttcacgcgc
    24001 cagcttagta atgcggtcgt aatcgcccgc ttccagcgca tctgccggaa ccagccagga
    24061 accaccgatg cacagcacgc ttttcagcgc caggtagtca cggtagttag ccggagaaat
    24121 accacccgtc gggcagaaac ggacctggga gaacggaccc gcgatcgcct gcagggcttt
    24181 cacgccgccg ttagcttcag ccgggaagaa tttgaactct ttcaaaccgt agtccatacc
    24241 cagcatcagt tcggaaacag tgctgatccc cggaatcaga ggaatagtcc cttcggtagc
    24301 agctttcagc agcggctcgg tcagacccgg gctaattgcg aactgtgcac ccgcttcagt
    24361 gacttctgcc agctgctgtg gattcagcac cgtaccggca cccacaatcg cttcaggcac
    24421 ttctttggcg atagcacgga tagcgtcaac tgcacactcg gtacgcagag tcacttccag
    24481 aacgcgcacc ccaccagcaa ccaacgcttt tgccatcggc accgcgtgtt ccagtttttt
    24541 taccacgata accggtacaa ccgggccggt ggtcaggatt gattctgcac ttgttttcca
    24601 gtttttcatc agagttttct ctcgcctgat tacaaatttg tcgtcttaaa aagtgataca
    24661 ggttgcgccc tgttcggcac cggacagttt ttcacgcaag gcgctgaata attcacgtcc
    24721 tgttcccacg cgtgacgcgc tcaggtcagg aatgtgcggt tcgcgagcag ccagttccgc
    24781 ttcgtctacc agcagcgtca gttcgcctgt ctgtccattc acacgaatga tgtccccgtc
    24841 gcgcactttt gccagcagcc cgccatcgta ggcttctggt gttacgtgga tagctgacgg
    24901 cactttacct gaagcgccgg agagtcgtcc atcggtaact aacgcaattt tgaaacaccg
    24961 gtccaataat acaccaagtg gcggcatgag tttatgtaat tctggcattc cgttcgcttt
    25021 tggcccctga tgacggacaa caacgacaca atcgcggtcc agcaaacccg cttcaaaggc
    25081 cggcataacg tcatgctggc tttcaaaaac aaccgctggc gcttcaatca cctggttctc
    25141 aaccggcacg gcagaggttt tcataaccgc acggcccagg ttaccgctta acacttttgt
    25201 cccaccatga tgagagaaag gttgttcgaa ggaagcgatc acattgctgt cgagtgattt
    25261 ttccgcccct tcccgccagt ccagttcacc attattcagc catggttcaa gggtataacg
    25321 agacagacca aaacctgcca ccgtattgac atcttcatgc agcaggcctg ctttgagcag
    25381 ttcacgcacc agaaccggta cgccacctgc cgcctggaag tggttaatat cggccggacc
    25441 gttcgggtag agacgtgcca tcagcggtac aacatcagaa aggtcagaga agtcatccca
    25501 gttaatctga ataccggccg cgcgcgccat cgccaccagg tgcatggtgt ggttagtgga
    25561 accaccggtc gccagcagtg caacgatacc gttcaccacc actttctcat cgatcatctt
    25621 accgatcggc atccattcat taccattacc ggtcatgcgt gtaacctgac gcgcagctgc
    25681 ggcggtcaaa gcatcgcgca gcggagaatc cggatgaaca aaagaagagc ctggcaactg
    25741 catccccata aactccacca ccatctggtt ggtgttggca gtaccgtaga aagtacatgt
    25801 tcccggcgca tggtaagacg cggcttctga ctccagtaag gccatgcggt ccactttacc
    25861 ttcggcataa agctggcgaa tacgcacttt ttctttattt ggcaaaccgc ttgccatcgg
    25921 tccagacggc acaaacaccg caggcaaatg accaaacgac agggctgcca tcgtcagacc
    25981 cgggacaatc ttgtcgcaca caccgaggaa cagagcacca tcaaacatgt tatgggacag
    26041 ccccaccgcc gcagacatcg ctatcacttc gcggcttagc agcgacaatt ccattccatc
    26101 ctgcccctgg gtgacaccat cacacatcgc cggaacaccg cccgcaacct gaccaaccgc
    26161 attcgcttca tgcagggctt tacgaatgat ttctggatag tgttcataag gctggtgcgc
    26221 ggagagcatg tcgttatagg aggtgatgat ggcgatattg ttacgcaaca tgcttttcaa
    26281 agaggctttg tcttctggct ggcaggcagc gaaaccgtgt gccaggttac cgcatgccaa
    26341 ctgcgaacga tgaacggtcg aagttttcgc ttgttctatc cgggcgagat aagcagagcg
    26401 agtctcgcgc gaacgttcaa tgattcgatt tgttacgcgt aacaattgtg gattcataaa
    26461 ggctcctgaa attgagttgt cagagcagga tgattcacaa cgcgtttcat tcagaggatt
    26521 tatgactgaa acgcctgtaa ccggagctca tagggcaaaa acgtttcagt cagtgtaata
    26581 aaaaaagcct cgtgggtgaa tccgcacgag gcctgaaagt gtaaaaattg ttctacaatc
    26641 tgcgcaagat catgttaccg gtaaaataac cataaaggat aagcgcagat attactcaaa
    26701 ctcattccag gaacgaccat cacgggtaat catcgccacc gaggcaacgg gtccccaggt
    26761 tccggcctga tacggtttcg gcgcatcatt gtccatcgcc cacgcctcag taatggagtc
    26821 tacccatttc caggcttctt ccacttcgtc gcgacgtaca aacagtgcct gaataccacg
    26881 catggtttcc agcagcaaac gttcataggc atccgccaga tgcgtctgat taaaggtttc
    26941 tgaatagctc agatccagct tggtgatttg caggttatgt ttgtggtcaa ggccaggaac
    27001 tttattcagt acctggatat ccacgccttc atcaggttgc agacggatag tcagtttatt
    27061 ctgcggcaga tcctgccacg attctttaaa cagattcagt tcaggtgttt tgaaatagac
    27121 cacgacttca gaacatttgg tcggcagacg tttaccagta cgcaggtaga atggcacacc
    27181 ggcccagcgc cagttatcaa tgtcgacgcg gatcgccacg aaagtttctg tattgctgct
    27241 cttgttcgcg ccctcttctt ccagatatcc cggcactttt ttgccctggg cgaagcccgc
    27301 agtatattgc ccgcgtacgg ttttttcgcg tacgttggag cggtcgatgc ggcgcagaga
    27361 cttcagtact ttcacttttt catcgcggat gctgtctgcg ctcaggtcag acggcggaga
    27421 catcgcaatc atgcaaagaa tttgcagcag gtggttctgg atcatgtcgc gcatctgacc
    27481 ggctttatca aaatagcccc agcgcccttc gatccccact tcttctgcca cggtaatctc
    27541 aacatgatca atggtgcgat tgtcccagtt attcacaaac agggagttag caaaacgcag
    27601 cgccaacagg ttcagcaccg tttctttacc aagatagtgg tcgatacggt aaacctggca
    27661 ctcctcgaag tattcgccaa cctgatcatt gatttcctgc gaggtcgcca gcgacgtccc
    27721 cagcggtttc tccatgacta cgcgtgccgg tttagcattc agttttgcct cgccaagccc
    27781 tttgcaaatt gcgccaaaag tgctgggcgg catggcaaag tagttaatgg tgatacgatt
    27841 tttttgatcc agcatcgcgc cgagacggct gaatgcagca gtgtcattga catcgagatt
    27901 acaaaaatcc agacgtgcac tcagggtgtc ccataaacct tcatcaatgg tttctttcat
    27961 gaaagtttcg agcgcctcgc ggacaacttt ggtatatgcc gctttatccc agtcagcacg
    28021 ccctacgccg ataatccggg tgtccgggtt gagctgaccg gctttttcca gttgatacag
    28081 ggaaggcagc aatttacgac gcgcaaggtc gcctttcgcg ccgaaaatga ccaggtcaca
    28141 ggcctgggct gtttgcgtta ccgccatgtc attctcctta agttaactaa cccggtactt
    28201 aagccagggt atacttgtaa ttttcttacg gtgcactgta ctgcttttac gagcttgcga
    28261 aaactgtaaa cgcttatcca cccgtgcgat tacgggaaaa gcgcgcaaag tgcggcaaaa
    28321 ctgataaaaa aatcatcgtt ttccattggg taaaaatctg acactgatca tgttatgaaa
    28381 aaaaataaca acttttttat ctgcttttgt cattaacacg gcacacaggc gtaatatctg
    28441 acaaaactgc atttcgattt ctttcagtgc ggaaatcgtc attacccgtg agtctcttta
    28501 catcatgaat atgctggaaa aaatccagtc tcagctggaa catttgagca aatcagagcg
    28561 caaagttgcc gaggtcattc tggcttcgcc cgataacgcg atccattcga gtattgctgc
    28621 tatggcactg gaagccaatg ttagcgaacc gacggtgaat cgtttctgtc gcagcatgga
    28681 cacgcgcggt tttcctgatt ttaaacttca tctggcacag agtctggcga atggcactcc
    28741 ctatgttaat cgcaatgtca atgaagatga cagcgttgaa tcatacacag ggaaaatatt
    28801 tgagtccgca atggcaacgc ttgatcatgt ccgtcattca ctggataaat ctgccatcaa
    28861 ccgcgccgtc gacttgctca ctcaggcaaa aaaaatcgcc tttttcggat taggctcttc
    28921 agccgccgtt gcccacgatg cgatgaataa gttctttcgt tttaatgttc cggtggtgta
    28981 ctccgatgat atcgtgctgc aacgcatgag ttgtatgaat tgtagcgacg gagacgtggt
    29041 ggtgctgatt tctcacactg gaagaacaaa aaatctggtc gagctggcgc agctggcacg
    29101 cgaaaacgac gccatggtga ttgccctcac ctctgcgggt accccgctcg cccgggaagc
    29161 aacgctggca attaccctcg acgtaccgga agatactgac atttatatgc ccatggtttc
    29221 tcgacttgca cagctgaccg tgatagatgt gctggcgaca ggatttactt tgcgacgcgg
    29281 tgcaaaattc agagataact tgaagcgggt caaagaagcg ctgaaggaat cgcgttttga
    29341 taagcagtta cttaatttaa gtgacgatcg ctaaaaacga ctgtcactgt cctaatctta
    29401 tacgacatcc gaatgagatt aatttatcgc catcgcggcg ttatttcatt cggatttcat
    29461 gttcaagcaa cacctggttg tttcagtcaa cggagtatta catgtccaga aggcttcgca
    29521 gaacaaaaat cgttaccacg ttaggcccag caacagatcg cgataataat cttgaaaaag
    29581 ttatcgcggc gggtgccaac gttgtacgta tgaacttttc tcacggctcg cctgaagatc
    29641 acaaaatgcg cgcggataaa gttcgtgaga ttgccgcaaa actggggcgt catgtggcta
    29701 ttctgggtga cctccagggg cccaaaatcc gtgtatccac ctttaaagaa ggcaaagttt
    29761 tcctcaatat tggggataaa ttcctgctcg acgccaacct gggtaaaggt gaaggcgaca
    29821 aagaaaaagt cggtatcgac tacaaaggcc tgcctgctga cgtcgtgcct ggagacatcc
    29881 tgctgctgga cgatggtcgc gtccagttaa aagtactgga agttcagggc atgaaagtgt
    29941 tcaccgaagt caccgtcggt ggtcccctct ccaacaataa aggtatcaac aaacttggcg
    30001 gcggtttgtc ggctgaagcg ctgaccgaaa aagacaaagc agacattaag actgcggcgt
    30061 tgattggcgt agattacctg gctgtctcct tcccacgctg tggcgaagat ctgaactatg
    30121 cccgtcgcct ggcacgcgat gcaggatgtg atgcgaaaat tgttgccaag gttgaacgtg
    30181 cggaagccgt ttgcagccag gatgcaatgg atgacatcat cctcgcctct gacgtggtaa
    30241 tggttgcacg tggcgacctc ggtgtggaaa ttggcgaccc ggaactggtc ggcattcaga
    30301 aagcgttgat ccgtcgtgcg cgtcagctaa accgagcggt aatcacggcg acccagatga
    30361 tggagtcaat gattactaac ccgatgccga cgcgtgcaga agtcatggac gtagcaaacg
    30421 ccgttctgga tggtactgac gctgtgatgc tgtctgcaga aactgccgct gggcagtatc
    30481 cgtcagaaac cgttgcagcc atggcgcgcg tttgcctggg tgcggaaaaa atcccgagca
    30541 tcaacgtttc taaacaccgt ctggacgttc agttcgacaa tgtggaagaa gctattgcca
    30601 tgtcagcaat gtacgcagct aaccacctga aaggcgttac ggcgatcatc accatgaccg
    30661 aatcgggtcg taccgcgctg atgacctccc gtatcagctc tggtctgcca attttcgcca
    30721 tgtcgcgcca tgaacgtacg ctgaacctga ctgctctcta tcgtggcgtt acgccggtgc
    30781 actttgatag cgctaatgac ggcgtagcag ctgccagcga agcggttaat ctgctgcgcg
    30841 ataaaggtta cttgatgtct ggtgacctgg tgattgtcac ccagggcgac gtgatgagta
    30901 ccgtgggttc tactaatacc acgcgtattt taacggtaga gtaagtacgt tgccggatgc
    30961 ggcgaaaacg ccacatccgg cctacagttc aatgatagtt caacagattt cgaatattct
    31021 gaagcaaact tgaacttatc atcaggcgaa ggcctctcct cgcgagaggc ttttttattt
    31081 gatgggataa agatctttgc gcttatacgg ctggatttcg cccggtttgc gagttttcag
    31141 caattttagt atccaggtgt attgttctgg tcgcggacca acaaaaatct cgacttcttc
    31201 attcatccgc cgcgcaatcg tatgatcatc cgcctctaac agatcatcca tcggtgggcg
    31261 cacctgaatc gtcagacgat gcgtcttgcc atcataaatc ggaaacagcg gtacaacgcg
    31321 cgcacggcac actttcatca aacgaccaat cgcgggcaac gtcgctttat aggtggcaaa
    31381 gaaatccaca aattcgctgt gctctgggcc atgatcctga tcgggtaaat aatatcccca
    31441 gtacccctga cgtaccgact ggatgaatgg tttaataccg tcatttctcg catgcagacg
    31501 accgccaaag cgacgacgca ccgtgttcca gacataatca aaaaccgggt tgccctgatt
    31561 atggaacatc gctgccattt tctgcccttg cgaggccatc agcatggcag gaatatcgac
    31621 ggcccaaccg tgcggcacca gaaagataac tttctcgtta ttacgccgca tctcttcgat
    31681 gatctccagc ccttgccagt caacgcgcgg ctgaattttc tccggcccgc gtattgccaa
    31741 ctcagccatc attgccatcg cttgcggcgc ggtggcaaac atctcatcaa caatcgcttc
    31801 gcgttcagct tcactacgtt ctggaaagca gagcgacaga ttgattaacg cacgacggcg
    31861 tgagcttttt cccagtcgtc cggcaaaacg tcccagccgt gccagaatgg gatcacggaa
    31921 ctttggcggc gttaaagcga tacccgccat cgctgctacg cccagccatg ctccccagta
    31981 gcgcgggtgg cgaaaggatt tatcaaactc aggaatgtat tcgctattat tttttttcgt
    32041 ttccatgctt ttccagtttc ggataaggca aaaatcaatc tggtgatagt gtagcggcgc
    32101 aacttgcccc gcaccaaata aaaaaagccg gtactgactg cgtaccggct gcgaatggat
    32161 gttaattaat caaaccgtag ctgcggcaca atctctttgg cctgcgccag gaattcgcga
    32221 cgatcggagc cggtcagccc ttcggtacgc ggcagttttg ccgtcagcgg gtttacggcc
    32281 tgctggttta tccatacttc atagtgcaga tgcggcccgg ttgaacgtcc ggtattaccg
    32341 gaaagcgcga tacggtcgcc acgtttcacc ttctgtcccg gtttcaccag aatcttgcgc
    32401 aagtgcatat aacgcgtggt gtagctgcga ccatgacgaa tagccacata ataacctgct
    32461 gcgccactgc gtttggcaac caccacttca ccgtcaccca ctgaaagcac tggcgtaccc
    32521 tgcggcatgg cgaaatcaac acctctgtgt ggtgcaacgc gaccggtcac cggattagta
    32581 cgacgcgggt taaagttaga cgagatacgg aactgtttcg ccgtcgggaa tcgcaagaat
    32641 cctttcgcca gaccagtacc gttacgatcg tagaatttgc catcttcagc gcggatagcg
    32701 taataatctt taccttctga acgcaaacgt acgcccagca gctggctttg ctcacgttta
    32761 ccatcaagca tttctcgaga cattaacacc gcaaattcat cgcctttttt cagtttgcgg
    32821 aaatccattt gccactgcat ggctttaatc actgcgctca cttcggcgct ggttaaaccg
    32881 gcgtttctgg cgctggcaac aaagcttccc ccgacggtac ctttcagcag attgttaacc
    32941 cactctcctt gctgcatttc gctggtcatt ttaaaaccgt tagcggcagt acggtcatag
    33001 gttcgggttt cacgacgaga cacttcccag gtgaggcgct gcagttcgcc gtccgcggtt
    33061 aatgtccagg agagttgttg accgattttc aggttacgca attctttgtc ggccgcagcc
    33121 agttgggtga tatcacccat atcaatacca tactgattga gaatgctgct tagcgtatcg
    33181 ccagtggaaa caacatattc atgcacgccc gcttcaccgg cgattttgtc atccagttcg
    33241 tcctggggaa tggcttcatc ttcttgtgca gcttgatcaa tcggctcact ggcttcaggt
    33301 aagagcgaac gaatttcgtt ctgttccagc tcaatggttt tgacaattgg cgtggcatca
    33361 cggtgataaa cataaggccg ccagacagcg acggccagag taagaacggt gagcgacccc
    33421 aacataacgc ggtgtggtcg cggtaaatta ttaaacgcca gggcgacaga gcgggctatc
    33481 tgttgcacgt aatcacttcc tcattaatct cctttcaggc agctcgcata ctggttggct
    33541 aattgactca ggaattctga atagcttgtt ttacccagtt tgatattcgt ccccagggga
    33601 tccaacgttc ccatacgaac ggatgtccct cgtgcgacgc tctcaacgac cgctggcctg
    33661 aactgtggct cagcaaaaac gcaggttgct ttttgctcaa ccaactgtgt tcttatttca
    33721 tgtaaacgct gcgcgccagg ttgaatctca gggttaacgg taaaatgacc aagcggtgtc
    33781 agtccaaact gtttttcgaa atagccgtaa gcatcgtgaa aaacgaaata acctttcccc
    33841 ttgagcggcg cgagctcgtt accaacctgc gtttcggttg aggctaattg tgcctcaaaa
    33901 tccttcaggt tggcgtcaag tttggctcga ctttgcggca taagttccac taattttcca
    33961 tggattgcaa ccgctgtagc ccgcgctatc tctggggaaa gccaaagatg catgttgaaa
    34021 tcgccgtgat ggtgatcttc gtcacttttt tccgcgtggt cgtgatcatc atcatcgccg
    34081 tgaatacttt tcatcagtag cggtttcaca tcttcaagct gcgcaatcgt tacctgcttc
    34141 gctcctggta atttgcttac cggtttttgc ataaacgctt ccatctccgg gccaacccaa
    34201 acgactaagt ccgcgttctg taagcgtttt acatccgatg ggcgcagtga ataatcatgt
    34261 tctgaagcgc cgtcaggaag taaaacctct gtttctgtta ccccatcagc aatggcagaa
    34321 gcgatgaacc caacgggttt aagcgaagcg acaacggcgg catctgcggc ctgtgttgca
    34381 cctccccaga gagcggcgga taatgctgcg aaaagaagcg tttttttatg taacataatg
    34441 cgaccaataa tcgtaatgaa tatgagaagt gtgatattat aacatttcat gactactgca
    34501 agactaaaat taacatgaca agtctggttt ccctggaaaa tgtctcggtt tcttttggcc
    34561 aacgccgcgt cctctctgat gtgtcgctgg aacttaaacc tggaaaaatt ttgactttac
    34621 ttgggccaaa tggcgcaggt aagtcgacac tggtacgggt agtgctcggg ctggtaacac
    34681 ccgatgaagg ggttatcaag cgcaacggaa aactgcgcat cggctatgta ccgcagaagc
    34741 tgtatctcga caccacgttg ccactgaccg taaaccgttt tttacgctta cgccctggta
    34801 cacataaaga agatattttg cctgcactga aacgtgtcca ggccgggcac ctgattaacg
    34861 caccgatgca aaagctctct ggtggcgaaa cgcagcgtgt actattagcg cgagcattgt
    34921 taaatcgccc gcaattatta gtgctggatg aacccactca aggcgtggat gtaaatggcc
    34981 aggtggcgtt atatgacctt attgaccaac tgcgtcgtga actggattgt ggcgttttaa
    35041 tggtttctca cgatctgcat ctggtgatgg caaaaaccga tgaagtgctg tgcctgaatc
    35101 accacatttg ttgttccggc acaccggaag ttgtttccct gcatccggag tttatttcaa
    35161 tgtttggtcc tcgtggtgct gaacaactgg gtatctatcg ccatcatcat aaccatcgtc
    35221 acgatttaca gggacgaatt gttttgcgtc ggggaaatga tcgctcatga ttgaattatt
    35281 atttcccggt tggttagccg ggatcatgct cgcctgtgcc gcgggtccgc tgggttcgtt
    35341 tgtagtctgg cgtcgtatgt cttatttcgg tgatacgctg gctcatgcct cattacttgg
    35401 cgtcgcgtgt ggtttgttgc tggacgtgaa tccattctat gcggtgattg ccgttacgct
    35461 gctgctggcg ggcggtctgg tatggctgga gaagcgtcca cagctggcga tcgacacgtt
    35521 attagggatt atggcgcaca gtgccctgtc gctgggcctg gtggtcgtga gtctgatgtc
    35581 taatattcgt gttgatttga tggcttacct gttcggtgat ttgctggcag tgacgccaga
    35641 agatctcatc tctattgcga ttggcgtggt catcgtggtg gctattttgt tctggcaatg
    35701 gcgcaatttg ctgtcaatga cgataagccc ggatctggcg tttgttgatg gtgtgaaatt
    35761 acagcgagtg aaattgttgt tgatgctggt gacggcattg acgattggtg tagcgatgaa
    35821 atttgtcggt gcgttgatta ttacttcgtt gctgattatt cctgctgcta ctgcgcgtcg
    35881 ctttgcccgc acgccggaac agatggctgg tgtcgctgtt ttggtgggga tggtggcagt
    35941 gactggcggt ttaacctttt ccgcggttta cgatacgccg gcgggtccgt cggtggtgct
    36001 atgtgcggca ctgttattta ttctcagtat gatgaaaaag caggccagct aatctatcgc
    36061 tgaacacatt tgtcggatgc ggcgcgagcg ccttatccga cctacggttc ggtatctctg
    36121 gtagtcctgg taagacgcga acagcgtcgc atcaggcata ttgccagtgc cggatgcggc
    36181 gcgagcgacc aatccgactt acggcatttc tggcggcgtt atgccaaagt gattccacgc
    36241 ccgcgtcgtc gccatacgcc cacgcggtgt acgctgcaaa aagccttgct gaatcaaata
    36301 aggttccagc acatcctcaa tggtttcacg ttcttcgcca atggctgccg ccaggttatc
    36361 cagacctaca ggtccaccaa agaacttatc gattaccgcc agcaacaatt tgcggtccat
    36421 ataatcgaaa ccttcagcat cgacattcaa catatccagc gcctgagcag cgatatctgc
    36481 cgagatggtg ccatcgtgct tcacttcggc gaaatcacgc actcgacgca gcagacggtt
    36541 ggcaatgcgc ggcgtaccgc gagcgcgacg agcaacttcc agcgcgccgt catcactcat
    36601 ctcaagcccc ataaagcgtg cgctgcgact gacgatatat tgcagatccg gcacctgata
    36661 aaactccaga cgttgcacaa taccaaaacg gtcgcgcaac ggtgatgtca gcgaacctgc
    36721 gcgcgtggtt gcaccaatca gggtaaacgg cggcaaatca attttaatgg agcgtgccgc
    36781 cggaccttca ccaatcatga tatccagttg gtagtcttcc attgccgggt acagcacttc
    36841 ttcaacaact ggcgatagac ggtggatctc atcaataaac agcacgtcat gcggttcaag
    36901 gttagtgagc atcgcagcca aatcgcccgc cttttccagc accggaccag aagtcgtgcg
    36961 taaattaacg cccatttcat tggcgacaat gttggcaagc gtagttttac ccaaccccgg
    37021 aggaccaaaa atcaacaaat gatcgagggc atcgccgcgc agtttcgctg ctttgatgaa
    37081 aatctccatc tgtgaacgaa cctgcggctg accaacatac tcttccagta atttggggcg
    37141 aatggcgcga tctgctacat cttccggcaa agtggtaccg gcagaaatca gacggtctgc
    37201 ttcaatcatc ctttacctca taacgcggcg cgtagggctt cgcgaattaa agtttcactg
    37261 ctggcgtcag ggcgagcgat tttgctcacc atgcggcttg cttcttgtgg tttatagccc
    37321 agcgccacca gcgcggcaac cgcttcttgt tcagcatcgt cggtcgccgg gctggcagga
    37381 gacgtgagta ccaggtcggc ggctggcgta aagagatcgc catgcaaacc tttaaatcgg
    37441 tctttcattt caacaatcaa gcgttcggcg gtttttttgc caatacccgg cagtttcacc
    37501 agtgccccca cttcttcacg ctcaacggca ttaacgaact gctgcgctga cattccggag
    37561 aggatcgcca gcgccaactt cgggccgacg ccgttggttt tgatcaactc tttgaacaat
    37621 gtgcgctctt gtttattgtt aaaaccgtac agcagttgcg cgtcttcacg caccacaaag
    37681 tgggtgaaaa cgatcgcttc ctgacccgct tcagggagtt cataaaaaca ggtcatcggc
    37741 atatgcactt catagcctac gccgcccact tcaattaaca ccagcggggg ttgtttttca
    37801 atgatgatgc ctctgagtct gcctatcaca tgacgctcct gcgtaatgaa tcaaagataa
    37861 tgctgtatga taaaaaaatg ctggatagat atccagcgaa ggataaagaa aacttgcgag
    37921 gtgtctcgat gaactgaaaa atggcacagt ataatttatt ctacaggtt
//
LOCUS       DAPOAV010000041        37361 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.041, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000041 DAPOAV010000000
VERSION     DAPOAV010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37361
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.041"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            3..767
                     /gene="ycaL"
                     /locus_tag="RN951_002329"
     CDS             3..767
                     /gene="ycaL"
                     /locus_tag="RN951_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706828.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallopeptidase YcaL"
                     /protein_id="HDX2527319.1"
                     /translation="MKNTKLLLAIATSAALLTGCQNTHGIDTNMAISSGLNAYKAATL
                     SDADAKAIANQGCAEMDSGNQVASKSSKYGKRLAKIAKALGNNINGTPVNYKVYMTSD
                     VNAWAMANGCVRVYSGLMDMMNDNEIEGVLGHELGHVALGHSLAEMKASYAIVAARDA
                     ISATSGVASQLSRSQLGDIAEGAINAKYSRDKESEADDFSFDLLKKRGISTQGLVGSF
                     EKLASLDGGRTQSMFDSHPPSTERAQHIRDRIASGK"
     gene            940..1623
                     /gene="cmk"
                     /locus_tag="RN951_002330"
     CDS             940..1623
                     /gene="cmk"
                     /locus_tag="RN951_002330"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HDX2527320.1"
                     /translation="MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLA
                     LAALHHHVDVASEDALVPLASHLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQ
                     VAAFPRVREALLRRQRAFRELPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRML
                     QLQEKGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTTLSIEQVIEKALQ
                     YARQKLALA"
     gene            1734..3407
                     /gene="rpsA"
                     /locus_tag="RN951_002331"
     CDS             1734..3407
                     /gene="rpsA"
                     /locus_tag="RN951_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HDX2527321.1"
                     /translation="MTESFAQLFEESLKEIETRPGSIVRGVVVAIDKDVVLVDAGLKS
                     ESAIPAEQFKNAQGELEIQVGDEVDVALDAVEDGFGETLLSREKAKRHEAWITLEKAY
                     EDAETVTGVINGKVKGGFTVELNGIRAFLPGSLVDVRPVRDTLHLEGKELEFKVIKLD
                     QKRNNVVVSRRAVIESENSAERDQLLENLQEGMEVKGIVKNLTDYGAFVDLGGVDGLL
                     HITDMAWKRVKHPSEIVNVGDEITVKVLKFDRERTRVSLGLKQLGEDPWVAIAKRYPE
                     GTKLTGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKVVNVGDVVEVMVLD
                     IDEERRRISLGLKQCKANPWQQFAETHNKGDRVEGKIKSITDFGIFIGLDGGIDGLVH
                     LSDISWNVAGEEAVREYKKGDEIAAVVLQVDAERERISLGVKQLAEDPFNNWVALNKK
                     GAIVTGKVTAVDAKGATVELADGVEGYLRASEASRDRVEDATLVLSVGDEVEAKFTGV
                     DRKNRAISLSVRAKDEADEKDAIATVNKQEDANFSNNAMAEAFKAAKGE"
     gene            3567..3851
                     /gene="ihfB"
                     /locus_tag="RN951_002332"
     CDS             3567..3851
                     /gene="ihfB"
                     /locus_tag="RN951_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit beta"
                     /protein_id="HDX2527322.1"
                     /translation="MTKSELIERLATQQSHIPAKTVEDAVKEMLEHMASTLAQGERIE
                     IRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG"
     gene            4059..6323
                     /locus_tag="RN951_002333"
     CDS             4059..6323
                     /locus_tag="RN951_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415433.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC family protein"
                     /protein_id="HDX2527323.1"
                     /translation="MKITTVGVCIISGIFPLLILPQLPGTLTLAFLTLFACVLAFIPV
                     KTVRYIALTLLFFVWGILSAKQILWAGETLTGATQDAIVEITATDGMTTHYGQITHLQ
                     GRRIFPASGLVMYGEYLPQAVCAGQQWSMKLKVRAVHGQLNDGGFDSQRYAIAQHQPL
                     TGRFLQASVIEPNCSLRAQYLASLQTTLQPYPWNAVILGLGMGERLSVPKEIKNIMRD
                     TGTAHLMAISGLHIAFAALLAAGLIRSGQIFLPGRWIHWQIPLIGGICCAAFYAWLTG
                     MQPPALRTMVALATWGMLKLSGRQWSGWDVWICCLAAILLMDPVAILSQSLWLSAAAV
                     AALIFWYQWFPCPEWQLPPVLRAVVSLIHLQLGITLLLMPVQIVIFHGISLTSFIANL
                     LAIPLVTFITVPLILAAMVVHLSGPLILEQGLWFLADRSLALLFWGLKSLPEGWINIA
                     ECWQWLSFSPWFLLVVWRLNAWRTLPAMCVAGGLLMCWPLWQKPRPDEWQLYMLDVGQ
                     GLAMVIARNGKAILYDTGLAWPEGDSGQQLIIPWLHWHNLEPEGVILSHEHLDHRGGL
                     DSILHIWPMLWIRSPLNWEHHQPCVRGEAWQWQGLRFSAHWPLQGSNDKGNNHSCVVK
                     VDDGTNSILLTGDIEAPAEQKMLSRYWQQVQATLLQVPHHGSNTSSSLPLIQRVNGKV
                     ALASASRYNAWRLPSNKVKHRYQLQGYQWIDTPHQGQTTVNFSAQGWRISSLREQILP
                     RWYHQWFGVPVDNG"
     gene            6360..8108
                     /gene="msbA"
                     /locus_tag="RN951_002334"
     CDS             6360..8108
                     /gene="msbA"
                     /locus_tag="RN951_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A ABC transporter ATP-binding
                     protein/permease MsbA"
                     /protein_id="HDX2527324.1"
                     /translation="MHNDKDLSTWQTFRRLWPTIAPFKAGLIVAGVALILNAASDTFM
                     LSLLKPLLDDGFGKTDRSVLVWMPLVVIGLMILRGITSYVSSYCISWVSGKVVMTMRR
                     RLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASIIGLFIMM
                     FYYSWQLSIILIVLAPIVSIAIRVVSKRFRNISKNMQNTMGQVTTSAEQMLKGHKEVL
                     IFGGQEVETKRFDKVSNRMRLQGMKMVSASSISDPIIQLIASLALAFVLYAASFPSVM
                     DSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEKDEGKRV
                     IERATGDVEFRNVTFTYPGRDVPALRNINLKIPAGKTVALVGRSGSGKSTIASLITRF
                     YDIDEGEILMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEQYSREQI
                     EEAARMAYAMDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEAT
                     SALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERGTHNDLL
                     EHRGVYAQLHKMQFGQ"
     gene            8105..9091
                     /gene="lpxK"
                     /locus_tag="RN951_002335"
     CDS             8105..9091
                     /gene="lpxK"
                     /locus_tag="RN951_002335"
                     /EC_number="2.7.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetraacyldisaccharide 4'-kinase"
                     /protein_id="HDX2527325.1"
                     /translation="MIEKIWSGESPLWRLLLPLSWLYGLVSGVIRLCYKLKLKRAWRA
                     PVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYGGKAESYPLLLSADTT
                     TAQAGDEPVLIYQRTDAPVAVSPVRSDAVKAILAQHPDVQIIVTDDGLQHYRLARDVE
                     IVVIDGVRRFGNGWWLPAGPMRERAGRLKSVDAVIVNGGVPRSGEIPMHLLPGQAVNL
                     RTGTRCDVAQLEHVVAMAGIGHPPRFFATLKMCGVQPEKCVPLADHQSLNHADVSALV
                     SAGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLTQLTLLASGN"
     gene            9128..10360
                     /gene="ycaQ"
                     /locus_tag="RN951_002336"
     CDS             9128..10360
                     /gene="ycaQ"
                     /locus_tag="RN951_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix DNA-binding protein YcaQ"
                     /protein_id="HDX2527326.1"
                     /translation="MSLPHLSLADARNLHLAAQGLLNKPRRRASLEDIPATISRMSLL
                     QIDTINIVARSPYLVLFSRLGNYPAQWLDESLARGELMEYWAHEACFMPRSDFRLIRH
                     RMLAPEKMGWKYKDAWMQEHEAEIAQLIQHIHDKGPVRSADFEHPRKGASGWWEWKPH
                     KRHLEGLFTAGKVMVIERRNFQRVYDLTHRVMPDWDDERDLVSQTEAEIIMLDNSARS
                     LGIFREQWLADYYRLKRPALAAWREARAEQQQIIAVHVEKLGNLWLHDDLLPLLERAL
                     AGKLTATHSAVLSPFDPVVWDRKRAEQLFDFSYRLECYTPAPKRQYGYFVLPLLHRGQ
                     LVGRMDAKMHRQTGILEVISLWLQEGIKPTTTLQKGLRQAITDFANWQQATRVTLGCC
                     PQGLFTDCRTGWEIDPVA"
     gene            10412..10594
                     /gene="ycaR"
                     /locus_tag="RN951_002337"
     CDS             10412..10594
                     /gene="ycaR"
                     /locus_tag="RN951_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YcaR"
                     /protein_id="HDX2527327.1"
                     /translation="MDHRLLEIIACPVCNGKLWYNQEKQELICKLDNLAFPLRDGIPV
                     LLETEARVLTADESKS"
     gene            10591..11337
                     /gene="kdsB"
                     /locus_tag="RN951_002338"
     CDS             10591..11337
                     /gene="kdsB"
                     /locus_tag="RN951_002338"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HDX2527328.1"
                     /translation="MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAER
                     IIVATDHEDVARAVEAAGGEVCMTSADHQSGTERLAEVVEKCAFSDDTVIVNVQGDEP
                     MIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATI
                     PWDRDRFAEGLETVGDNFLRHLGIYGYRAGFIRRYVNWQPSPLEHIEMLEQLRVLWYG
                     EKIHVAVAQEVPGTGVDTPEDLERVRAEMR"
     gene            11491..12384
                     /locus_tag="RN951_002339"
     CDS             11491..12384
                     /locus_tag="RN951_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbJ family phosphotransferase"
                     /protein_id="HDX2527329.1"
                     /translation="MEQLRAELSHLLGEKLSRIECVNEKADTALWALYDSQGNPMPLM
                     VRSFSTPGKARQLAWKTTMLARSGTVRMPTIYGVMTHEEHPGPDVLLLERMRGVSVEA
                     PARTPERWEQLKDQIVEALLAWHRQDSRGCVGAVDNTQENFWPSWYRQHVEVLWTTLN
                     QFNNTGLTMQDKRILFRTRECLPALFEGFNDNCVLIHGNFCLRSMLKDSRSDQLLAMV
                     GPGLMLWAPREYELFRLMDNSLAEDLLWSYLQRAPVAESFIWRRWLYVLWDEVAQLVN
                     TGRFSRRNFDLASKSLLPWLA"
     gene            complement(12361..13140)
                     /gene="elyC"
                     /locus_tag="RN951_002340"
     CDS             complement(12361..13140)
                     /gene="elyC"
                     /locus_tag="RN951_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope biogenesis factor ElyC"
                     /protein_id="HDX2527330.1"
                     /translation="MLFTLKKVIGNMLLPLPLMLLIIGAGLALLWFSRFQKTGKIFIS
                     IGWLALLLLSLQPVADRLLRPIESTYPTWNNSQKVDYIVVLGGGYTWNPQWAPSSNLI
                     NNSLPRLNEGIRLWRENPGSKLIFTGGVAKTNTVSTAEVGARVAQSLGVPREQIITLD
                     LPKDTEEEAAAVKQAIGDAPFLLVTSASHLPRAMIFFQQEGLNPLPAPANQLAIDSPL
                     NPWERAIPSPVWLMHSDRVGYETLGRIWQWLKGSSGEPRQE"
     gene            13276..14061
                     /gene="cmoM"
                     /locus_tag="RN951_002341"
     CDS             13276..14061
                     /gene="cmoM"
                     /locus_tag="RN951_002341"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine 5-oxyacetic acid(34)
                     methyltransferase CmoM"
                     /protein_id="HDX2527331.1"
                     /translation="MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQ
                     KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAA
                     QDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNM
                     VAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREK
                     HQQRDCYEALLELETRYCRQEPYITLGRYIHVTARKPQSKDKV"
     gene            14058..15380
                     /gene="mukF"
                     /locus_tag="RN951_002342"
     CDS             14058..15380
                     /gene="mukF"
                     /locus_tag="RN951_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukF"
                     /protein_id="HDX2527332.1"
                     /translation="MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLD
                     GEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYR
                     LTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVYAPL
                     KYSVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLREL
                     QDTLEAAGDKLQANLLRIQDATMTHDDLRFVDRLVFDLQSKLDRIISWGQQSIDLWIG
                     YDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALTYANADRLLDMRDEEMALR
                     DEEVTGELPEDLEYEEFNEIREQLAAIIEEQLAVYKTRQVPLDLGLVVREYLSQYPRA
                     RHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY"
     gene            15361..16065
                     /gene="mukE"
                     /locus_tag="RN951_002343"
     CDS             15361..16065
                     /gene="mukE"
                     /locus_tag="RN951_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415443.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukE"
                     /protein_id="HDX2527333.1"
                     /translation="MSSTNIEQVMPVKLAQALANPLFPALDSALRSGRHIGLDELDNH
                     AFLMDFQEYLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLSELDMMVGKILCYL
                     YLSPERLANEGIFTQQELYDELLTLADEAKLLKLVNNRSTGSDVDRQKLQEKVRSSLN
                     RLRRLGMVWFMGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMPIENHLQ
                     LNDETEENQPDSGEEE"
     gene            16065..20525
                     /gene="mukB"
                     /locus_tag="RN951_002344"
     CDS             16065..20525
                     /gene="mukB"
                     /locus_tag="RN951_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukB"
                     /protein_id="HDX2527334.1"
                     /translation="MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTM
                     AAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVV
                     GVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLPLNELKDKLEAM
                     EGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLR
                     DYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMR
                     HANERRVHLDKALEFRRELHTSRQQLAAEQYKHVDMARELAEHNGAEGDLEADYQAAS
                     DHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQEENEARAEAAELEV
                     DELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKELCHLPDLTADCAAEWLETFQAK
                     ELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARNEAWDVARELLREGVDQ
                     RHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNFDIDELEALHQELEARI
                     ASLSDSVSNAREERMALCQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTS
                     SQDVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFG
                     GVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEHLEGLTDCPEDLYLIEGD
                     PQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLS
                     ERFATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDPEAEIRQLNSRRVELERALSNHE
                     NDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQ
                     FGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALTEVVQRRAHFSY
                     SDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLSQYNQVLASLKSSYDT
                     KKELLNDLQRELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAE
                     MDNLTRKLRKLERDYFEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADDL
                     RSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQDIIR
                     TDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGL
                     QNVSFGQVNSVRLNVNVRETHAMLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLN
                     PQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSIL
                     VMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPE
                     NISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGTDEAPSQAS"
     gene            20786..22633
                     /gene="ldtD"
                     /locus_tag="RN951_002345"
     CDS             20786..22633
                     /gene="ldtD"
                     /locus_tag="RN951_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HDX2527335.1"
                     /translation="MLLNMMCGRRLSAISLCLAVTFAPLFNAQADEPEVIPGDSPVAV
                     SEQGEALPQAQATAIMAGIQPLPEGAAEKARTQIESQLPAGYKPVYLNQLQLLYAARD
                     MQPMWENRDAVKAFQQQLAEVAIAGFQPQFNKWVELLTDPGVNGMARDVVLSDAMMGY
                     LHFIANIPVKGTRWLYSSKPYALATPPLSVINQWQLALDKGQLPTFVAGLAPQHPQYA
                     AMHESLLALLCDTKPWPQLTGKATLRPGQWSNDVPALREILQRTGMLDGGPKITLPGD
                     DTPTDAVVSPSAVTVETAETKPMDKQTTSRSKPAPAVRAAYDNELVEAVKRFQAWQGL
                     GADGAIGPATRDWLNVTPAQRAGVLALNIQRLRLLPTELSTGIMVNIPAYSLVYYQNG
                     NQVLDSRVIVGRPDRKTPMMSSALNNVVVNPPWNVPPTLARKDILPKVRNDPGYLESH
                     GYTVMRGWNSREAIDPWQVDWSTITASNLPFRFQQAPGPRNSLGRYKFNMPSSEAIYL
                     HDTPNHNLFKRDTRALSSGCVRVNKASDLANMLLQDAGWNDKRISDALKQGDTRYVNI
                     RQSIPVNLYYLTAFVGADGRTQYRTDIYNYDLPARSSSQIVSKAEQLIR"
     gene            22814..23362
                     /locus_tag="RN951_002346"
     CDS             22814..23362
                     /locus_tag="RN951_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbK family protein"
                     /protein_id="HDX2527336.1"
                     /translation="MDKFDANRRKLLALGGVALGAAILPTPAFATLSTPRPRILTLNN
                     LHTGESIKAEFFDGRGYIQEELAKLNHFFRDYRANKIKSIDPGLFDQLYRLQGLLGTR
                     KPVQLISGYRSIDTNNELRARSRGVAKKSYHTKGQAMDFHIEGIALSNIRKAALSMRA
                     GGVGYYPRSNFVHIDTGPARHW"
     gene            23389..24036
                     /gene="gloC"
                     /locus_tag="RN951_002347"
     CDS             23389..24036
                     /gene="gloC"
                     /locus_tag="RN951_002347"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase GloC"
                     /protein_id="HDX2527337.1"
                     /translation="MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDD
                     SGLTLMQILLTHGHLDHVGAAAELAQHYGVPVFGPEKEDEFWLQGLPAQSRMFGLEEC
                     QPLTPDRWLNEGDTISIGNVTLQVLHCPGHTPGHVVFFDDRAKLLISGDVIFKGGVGR
                     SDFPRGDHNQLISSIKDKLLPLGDDVIFIPGHGPLSTLGYERLHNPFLQDEMPVW"
     gene            complement(24258..25448)
                     /gene="aspC"
                     /locus_tag="RN951_002348"
     CDS             complement(24258..25448)
                     /gene="aspC"
                     /locus_tag="RN951_002348"
                     /EC_number="2.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009653304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate transaminase"
                     /protein_id="HDX2527338.1"
                     /translation="MFENITAAPADPILGLADLFRADERPGKINLGIGVYKDETGKTP
                     VLTSVKKAEQYLLENETTKNYLGIDGIPEFGRCTQELLFGKGSALINDKRARTAQTPG
                     GTGALRVAADFLAKNTSVKRVWVSNPSWPNHKSVFNSAGLEVREYAYYDAENHTLDFD
                     ALINSLNEAQAGDVVLFHGCCHNPTGIDPTLEQWQTLAQLSVEKGWLPLFDFAYQGFA
                     RGLEEDAEGLRAFAAMHKELIVASSYSKNFGLYNERVGACTLVAADSETVDRAFSQMK
                     AAIRANYSNPPAHGASVVATILSNDALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGA
                     NRDFSFIIKQNGMFSFSGLTKEQVLRLREEFGVYAVASGRVNVAGMTPDNMAPLCEAI
                     VAVL"
     gene            complement(25633..26721)
                     /gene="ompF"
                     /locus_tag="RN951_002349"
     CDS             complement(25633..26721)
                     /gene="ompF"
                     /locus_tag="RN951_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpF"
                     /protein_id="HDX2527339.1"
                     /translation="MMKRNILAVIVPALLVAGTANAAEIYNKDGNKVDLYGKAVGLHY
                     FSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNK
                     TRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVAT
                     YRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADR
                     TNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKT
                     QDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVD
                     YIINQIDSDNKLGVGSDDTVAVGIVYQF"
     gene            complement(27324..28724)
                     /gene="asnS"
                     /locus_tag="RN951_002350"
     CDS             complement(27324..28724)
                     /gene="asnS"
                     /locus_tag="RN951_002350"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDX2527340.1"
                     /translation="MSVVPVADVLQGRVAVDSEVTVRGWVRTRRDSKAGISFLAVYDG
                     SCFDPVQAVINNSLPNYNEDVLRLTTGCSVIVTGKVVASPGQGQQFEIQASKVEVAGW
                     VEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFNEQGFFWV
                     STPLITASDTEGAGEMFRVSTLDLENLPRNDQGKVDFDKDFFGKESFLTVSGQLNGET
                     YACALSKIYTFGPTFRAENSNTSRHLAEFWMLEPEVAFANLNDIAGLAEAMLKYVFKA
                     VLEERADDMKFFAERVDKDAVSRLERFIEADFAQVDYTDAVTILENCGRKFENPVYWG
                     VDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIG
                     GSQREERLDVLDERMLEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQN
                     VRDVIPFPRTPRNASF"
     gene            complement(28893..30095)
                     /gene="pncB"
                     /locus_tag="RN951_002351"
     CDS             complement(28893..30095)
                     /gene="pncB"
                     /locus_tag="RN951_002351"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HDX2527341.1"
                     /translation="MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGD
                     DLLGIYADAIREQVQAMQHLRLQDDEYQWLSALPFFKADYLNWLREFRFNPEQVTVSN
                     DNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTLESKLVDFSAL
                     TAGLDMSRFHLMDFGTRRRFSREVQETIVKRLQQESWFVGTSNYDLARRLSLTPMGTQ
                     AHEWFQAHQQISPDLANSQRAALAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASR
                     YQGLRHDSGDPVEWGEKAIAHYEKLGIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQL
                     SFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFD
                     LPHIKKAS"
     gene            30361..32973
                     /gene="pepN"
                     /locus_tag="RN951_002352"
     CDS             30361..32973
                     /gene="pepN"
                     /locus_tag="RN951_002352"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000193787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase N"
                     /protein_id="HDX2527342.1"
                     /translation="MTQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKTVVTAVSQAVR
                     HGASDAPLRLNGEDLKLVSVHINDEPWTAWKEEEGALVISNLPERFTLKIINEISPAA
                     NTALEGLYQSGDALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKIKYPFLLSNGN
                     RVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRG
                     NLDRAPWAMTSLKNSMKWDEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYV
                     LARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDL
                     GSRAVNRINNVRTMRGLQFAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIH
                     TLLGEENFQKGMQLYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPIVTV
                     KDDYNPETEQYTLTISQRTPATPDQAEKQPLHIPFAIELYDNEGKVIPLQKGGHPVNS
                     VLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSRWD
                     AAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKIDPALAAEILTLPSVNE
                     MAELFDIIDPIAIAEVREALTRTLATELADELLAIYNANYQSEYRVEHEDIAKRTLRN
                     ACLRFLAFGETHLADVLVSKQFHEANNMTDALAALSAAVAAQLPCRDALMQEYDDKWH
                     QNGLVMDKWFILQATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFH
                     AEDGSGYLFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLEN
                     LSGDLYEKITKALA"
     gene            complement(33016..33783)
                     /gene="ssuB"
                     /locus_tag="RN951_002353"
     CDS             complement(33016..33783)
                     /gene="ssuB"
                     /locus_tag="RN951_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonates ABC transporter ATP-binding
                     protein"
                     /protein_id="HDX2527343.1"
                     /translation="MNTARLNQGTPLLLNAVSKHYAENIVLNQLDLHIPAGQFVAVVG
                     RSGGGKSTLLRLLAGLETPTAGDVLAGTTPLAEIQEDTRMMFQDARLLPWKSVIDNVG
                     LGLKGQWRDAARRALAAVGLENRAGEWPAALSGGQKQRVALARALIHRPGLLLLDEPL
                     GALDALTRLEMQDLIVSLWQEHGFTVLLVTHDVSEAVAMADRVLLIEEGKIGLDLTVD
                     IPRPRRLGSVRLAELEAEVLQRVMQRGESETRLRKQG"
     gene            complement(33780..34571)
                     /gene="ssuC"
                     /locus_tag="RN951_002354"
     CDS             complement(33780..34571)
                     /gene="ssuC"
                     /locus_tag="RN951_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415454.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonate ABC transporter permease
                     SsuC"
                     /protein_id="HDX2527344.1"
                     /translation="MATPVKKWLLRVAPWFLPVGIVAVWQLASSVGWLSTRILPSPEG
                     VVTAFWTLSASGELWQHLAISSWRALIGFSIGGSLGLILGLISGLSRWGERLLDTSIQ
                     MLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARS
                     YGLSGIPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETISANSGIGYLAMNAREF
                     LQTDVVVVAIILYALLGKLADVSAQLLERLWLRWNPAYHLKEATV"
     gene            complement(34582..35727)
                     /gene="ssuD"
                     /locus_tag="RN951_002355"
     CDS             complement(34582..35727)
                     /gene="ssuD"
                     /locus_tag="RN951_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMNH2-dependent alkanesulfonate monooxygenase"
                     /protein_id="HDX2527345.1"
                     /translation="MSLNMFWFLPTHGDGHYLGTEEGSRPVDHGYLQQIAQAADRLGY
                     TGVLIPTGRSCEDAWLVAASMIPVTQRLKFLVALRPSVTSPTVAARQAATLDRLSNGR
                     ALFNLVTGSDPQELAGDGVFLDHSERYEASAEFTQVWRRLLQRETVDFNGKHIHVRGA
                     KLLFPAIQQPYPPLYFGGSSDVAQELAAEQVDLYLTWGEPPELVKEKIEQVRAKAAAH
                     GRKIRFGIRLHVIVRETNDEAWQAAERLISHLDDETIAKAQAAFARTDSVGQQRMAAL
                     HNGKRDNLEISPNLWAGVGLVRGGAGTALVGDGPTVAARINEYAALGIDSFVLSGYPH
                     LEEAYRVGELLFPLLDVAIPEIPQPQPLNPQGEAVANDFIPRKVAQS"
     gene            complement(35724..36683)
                     /gene="ssuA"
                     /locus_tag="RN951_002356"
     CDS             complement(35724..36683)
                     /gene="ssuA"
                     /locus_tag="RN951_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415456.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonate ABC transporter
                     substrate-binding protein SsuA"
                     /protein_id="HDX2527346.1"
                     /translation="MRNIIKLALAGLLSVSTFAVAAESSPEALRIGYQKGSIGMVLAK
                     SHQLLEKRYPESKISWVEFPAGPQMLEALNVGSIDLGSTGDIPPIFAQAAGADLVYVG
                     VEPPKPKAEVILVAENSPIKTVADLKGHKVAFQKGSSSHNLLLRALRQAGLKFTDIQP
                     TYLTPADARAAFQQGNVDAWAIWDPYYSAALLQGGVRVLKDGTDLNQTGSFYLAARPY
                     AEKNGAFIQGVLATFSEADALTRSQREQSIALLAKTMGLPAPVIASYLDHRPPTTIKP
                     VNAEVAALQQQTADLFYENRLVPKKVDIRQRIWQPTQLEGKQL"
     gene            complement(36676..37251)
                     /gene="ssuE"
                     /locus_tag="RN951_002357"
     CDS             complement(36676..37251)
                     /gene="ssuE"
                     /locus_tag="RN951_002357"
                     /EC_number="1.5.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HDX2527347.1"
                     /translation="MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAP
                     EDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVV
                     LPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYHHRPQFTPNLQTR
                     LDTALETFWQALHRRDVQVPDLLSLRGNAHA"
BASE COUNT         9138 a         9383 c         9957 g         8883 t
ORIGIN      
        1 acatgaagaa tactaaatta ctgctggcga ttgcgacctc tgcagcatta ctgacagggt
       61 gtcaaaatac ccacggtatt gataccaata tggctatcag ctccggttta aatgcctata
      121 aagcagcaac attaagcgat gccgatgcaa aagcgattgc caatcagggc tgtgccgaaa
      181 tggacagcgg caatcaagtc gcaagtaaat ccagcaagta cggtaaacgt ctggcaaaaa
      241 tcgccaaagc attgggtaac aatattaatg gcacgccggt caactataag gtttatatga
      301 ccagcgacgt caacgcatgg gcgatggcga acggctgtgt tcgtgtctac agtggcctga
      361 tggacatgat gaatgacaac gaaattgaag gcgttctggg ccatgaactg ggccacgtcg
      421 cgttgggtca ctcgctggct gaaatgaaag cttcttatgc gatcgttgcc gcacgcgatg
      481 ccatttcagc taccagcggt gtggcttccc agctttcccg ctcacaatta ggtgatatcg
      541 cagaaggcgc tatcaatgct aaatactccc gtgataaaga gtccgaagca gatgatttct
      601 cctttgatct gttgaagaaa cgtggcatca gcacccaggg gctggttggc agctttgaaa
      661 aactggctag cctggatggc ggtcgcaccc agtccatgtt tgactctcac ccaccatcaa
      721 cagagcgtgc gcaacacatc cgtgatcgta tcgcctctgg taagtaaatc attgtcatct
      781 ttcgggctgg tcttctgcca gcccgctata attgcgcaat aaatccccat ctgaatacag
      841 acaaaactgg tttttgcaca caacgttaac gatttgtggc gtcggcgcgt ataatgcgcg
      901 cggttatgtt aacggtacgc ctgttttaag gagataaaga tgacggcaat tgccccggtt
      961 attaccattg atggcccaag cggtgcaggg aaaggcacct tgtgtaaggc tatggcggaa
     1021 gcgttgcaat ggcatctgct ggactcgggt gcaatttatc gcgtactggc attggcggca
     1081 ttacatcacc atgttgatgt tgcgtcggaa gatgcgctgg taccgctggc atcccatctg
     1141 gatgtacgtt ttgtgtcgac caatggcaat ctggaagtga tcctcgaagg ggaagatgtc
     1201 agcggcgaaa ttcgtactca ggaagtggcg aatgcagctt cacaagtcgc ggcattccca
     1261 cgcgttcgtg aagcattatt gcgtcgccaa cgcgcgtttc gcgaattacc aggtctgatt
     1321 gccgatggcc gcgacatggg aacggtggta ttccctgatg caccagtgaa aattttcctt
     1381 gacgcctcct cggaagaacg tgcgcatcgc cgcatgctac agttgcagga gaagggcttt
     1441 agtgttaact ttgagcgcct tttggccgag atcaaagaac gcgacgaccg cgatcgtaac
     1501 cgagcggtag cgccactggt tccggcagcc gatgctttag tgttggattc caccacctta
     1561 agcattgagc aagtgattga aaaagcgcta caatacgcgc gccagaaatt ggctctcgca
     1621 taagcgaccg aatttgcagt acccccgttg caatggaatg acagcgggta tgttaaacaa
     1681 ccccatccgg catggagcca ggtggacgtt aaatataaac ctgaagatta aacatgactg
     1741 aatcttttgc tcaactcttt gaagagtcct taaaagaaat cgaaacccgc ccgggttcta
     1801 tcgttcgtgg cgttgttgtt gctatcgaca aagacgtagt actggttgac gctggtctga
     1861 aatctgagtc cgccatcccg gctgagcagt tcaaaaacgc ccagggcgag ctggaaatcc
     1921 aggtaggtga cgaagttgac gttgctctgg acgcagtaga agacggcttc ggtgaaactc
     1981 tgctgtcccg tgagaaagct aaacgtcacg aagcctggat cacgctggaa aaagcttacg
     2041 aagatgctga aactgttacc ggtgttatca acggcaaagt taagggcggc ttcactgttg
     2101 agctgaacgg tattcgtgcg ttcctgccag gttctctggt agacgttcgt ccggtgcgtg
     2161 acactctgca cctggaaggc aaagagcttg aatttaaagt aatcaagctg gatcagaagc
     2221 gcaacaacgt tgttgtttct cgtcgtgccg ttatcgaatc cgaaaacagc gcagagcgcg
     2281 atcagctgct ggaaaacctg caggaaggca tggaagttaa aggtatcgtt aagaacctca
     2341 ctgactacgg tgcattcgtt gatctgggcg gcgttgacgg cctgctgcac atcactgaca
     2401 tggcctggaa acgcgttaag catccgagcg aaatcgtcaa cgtgggcgac gaaatcactg
     2461 ttaaagtgct gaagttcgac cgcgaacgta cccgtgtatc cctgggcctg aaacagctgg
     2521 gcgaagatcc gtgggtagct atcgctaaac gttatccgga aggtaccaaa ctgactggtc
     2581 gcgtgaccaa cctgaccgac tacggctgct tcgttgaaat cgaagaaggc gttgaaggcc
     2641 tggtacacgt ttccgaaatg gattggacca acaaaaacat ccacccgtcc aaagttgtta
     2701 acgttggcga tgtagtggaa gttatggttc tggatatcga cgaagaacgt cgtcgtatct
     2761 ccctgggtct gaaacagtgc aaagctaacc cgtggcagca gttcgcggaa acccacaaca
     2821 agggcgaccg tgttgaaggt aaaatcaagt ctatcactga cttcggtatc ttcatcggcc
     2881 tggacggcgg catcgacggc ctggttcacc tgtctgacat ctcctggaac gttgcaggcg
     2941 aagaagcagt tcgtgaatac aaaaaaggcg acgaaatcgc tgcagttgtt ctgcaggttg
     3001 acgcagaacg tgaacgtatc tccctgggcg ttaaacagct cgcagaagat ccgttcaaca
     3061 actgggttgc tctgaacaag aaaggcgcta tcgtaaccgg taaagtaact gcagttgacg
     3121 ctaaaggcgc aaccgtagaa ctggctgacg gcgttgaagg ttacctgcgt gcttctgaag
     3181 catcccgtga ccgcgttgaa gacgctaccc tggttctgag cgttggcgac gaagttgaag
     3241 ctaaattcac cggcgttgat cgtaaaaacc gcgcaatcag cctgtctgtt cgtgcgaaag
     3301 acgaagctga cgagaaagat gcaatcgcaa ctgttaacaa acaggaagat gcaaacttct
     3361 ccaacaacgc aatggctgaa gctttcaaag cagctaaagg cgagtaattc tctgactctt
     3421 cgggattttt attccgaagt ttgttgagtt tacttgacag attgcaggtt tcgtcctgta
     3481 atcaagcact aagggcggct acggccgccc ttaatcaatg cagcaacagc agccgcttaa
     3541 tttgccttta aggaaccgga ggaatcatga ccaagtcaga attgatagaa agacttgcca
     3601 cccagcaatc gcacattccc gccaagacgg ttgaagatgc agtaaaagag atgctggagc
     3661 atatggcctc gactcttgcg cagggcgagc gtattgaaat ccgcggtttc ggcagtttct
     3721 ctttgcacta ccgcgcacca cgtaccggac gtaatccgaa gactggcgat aaagtagaac
     3781 tggaaggaaa atacgttcct cactttaaac ctggtaaaga actgcgcgat cgcgccaata
     3841 tttacggtta agttttttac tcaaacttga acgagagaaa agcacctgtc gggtgctttt
     3901 ttcatttctc taatctggaa ctggaagctg cctcgcagag ttttgaacag ttttcaccct
     3961 ttcgttaaat tcttctgaat atgcctcggg gaacgcaaaa ttcccaccag acaaccactc
     4021 aacaaagttg cacactttcc ataaacaggg aggggtgcat gaaaataacg acagtcggtg
     4081 tatgcataat tagcggaatt tttccgttgc tgattttgcc ccaattgcct gggacattaa
     4141 cccttgcgtt tctgactctc ttcgcctgcg tactggcatt tatccctgtt aaaaccgtcc
     4201 gttatatcgc gctgacgttg ctgtttttcg tttggggcat attatcagca aagcaaattt
     4261 tgtgggcagg agaaacctta actggcgcga cgcaggatgc aattgttgag atcactgcaa
     4321 ctgacggcat gaccactcat tacggtcaaa ttactcatct acaaggtcga cgtatattcc
     4381 ctgcgtcagg tctcgtgatg tatggcgaat atcttccgca agcggtttgt gctggacaac
     4441 aatggtcaat gaaactcaaa gttcgtgcag ttcatggcca acttaatgat ggcggctttg
     4501 atagccagcg ttatgccatt gcccagcatc agccgctcac cggccgtttt ctgcaggcaa
     4561 gtgtcattga accgaattgt agcctgcgtg cacagtatct ggcgtcacta caaacaacgc
     4621 tgcaacccta tccgtggaat gcggttattc ttggtttagg tatgggggaa cggttatccg
     4681 tccccaaaga aatcaaaaat atcatgcgcg atactggaac ggcgcattta atggcgatat
     4741 cgggattgca catcgctttt gcggcgttgc tggctgccgg actcattcgc agtggacaaa
     4801 tttttctgcc tgggcgctgg atccactggc aaataccatt aattggcgga atctgctgtg
     4861 ctgcttttta tgcctggttg acgggaatgc aacctcctgc attgcgtacc atggtggcgc
     4921 ttgctacgtg gggaatgctt aagttaagtg ggcgacagtg gagtggctgg gatgtatgga
     4981 tatgttgtct ggcggcaatt ttgctgatgg atcctgttgc cattctctcg caaagtttat
     5041 ggctctctgc cgctgcggtc gcggcattga tattttggta tcagtggttt ccctgtcctg
     5101 agtggcaact gccgccggta ttgcgtgcag ttgtttccct catccatctg caactgggaa
     5161 tcacacttct gcttatgccc gtgcaaatcg tcatatttca tggcattagt ctgacctcgt
     5221 ttattgcaaa tctattagca attcccttgg tgacatttat cacggttccg ttgatcctcg
     5281 ccgcgatggt tgtgcattta agcgggccgt taatcctgga gcaagggtta tggtttcttg
     5341 ccgaccggtc tttggcttta cttttctggg ggttaaagag tttgccggaa gggtggatca
     5401 acattgctga atgttggcaa tggctatcat tttccccatg gttcttactg gtggtatggc
     5461 gattaaacgc ctggcgaacg ttgccagcaa tgtgtgtggc tggaggcttg ctgatgtgct
     5521 ggccgctgtg gcaaaaacct cgacctgacg agtggcagct gtacatgctt gatgtcgggc
     5581 aagggctggc aatggtgata gccagaaacg gcaaagcgat tctctatgac acaggactgg
     5641 cctggcctga aggggatagt gggcaacaac tgattatccc ctggctccac tggcataatc
     5701 ttgaaccgga aggcgttatt ctgagccatg aacatctgga tcaccgggga gggctggatt
     5761 caatattgca tatatggccg atgttatgga tcagaagtcc gttaaactgg gaacatcatc
     5821 agccctgtgt gcgtggcgaa gcgtggcaat ggcaaggatt gcgtttcagc gcgcactggc
     5881 ctttacaagg tagcaacgat aaaggaaata accattcctg tgtggttaag gttgatgacg
     5941 ggacgaatag cattcttcta accggtgata ttgaagcccc agctgaacaa aagatgctaa
     6001 gccgttactg gcagcaagtg caggcaacat tgcttcaggt acctcaccat ggcagtaata
     6061 cctcatcatc gttgccatta attcagcgag tgaatggaaa agtggcactc gcatcggcat
     6121 cgcgctataa cgcatggcga ctgccctcta acaaagttaa gcatcgctat caactgcaag
     6181 gatatcaatg gattgatact ccacatcaag gtcaaacaac ggtcaatttt tcagcgcaag
     6241 gctggcggat tagcagcctc agggagcaaa ttttacctcg ttggtatcat cagtggtttg
     6301 gcgtgccagt ggataacggg tagaatatgc ggctatttca acaaatgctg gttttttgaa
     6361 tgcataacga caaagatctc tctacgtggc agacattccg ccgactgtgg ccaaccattg
     6421 cgcctttcaa agcgggtctg atcgtggcgg gcgtagcgtt aatcctcaac gcagccagcg
     6481 ataccttcat gttatcgctc cttaagccac ttcttgatga tggctttggt aaaacagatc
     6541 gctccgtgct ggtgtggatg ccgctggtgg tgatcgggct gatgatttta cgtggtatca
     6601 ccagctatgt ctccagctac tgtatctcct gggtatcagg aaaggtggta atgaccatgc
     6661 gtcgccgcct gtttggtcac atgatgggaa tgccagtttc attctttgac aaacagtcaa
     6721 cgggtacgct gttgtcacgt attacctacg attccgaaca ggttgcttct tcttcttccg
     6781 gcgcactgat tactgttgtg cgtgaaggtg cgtcgatcat cggcctgttc atcatgatgt
     6841 tctattacag ttggcaactg tcgatcattt tgattgtgct ggcaccgatt gtttcgattg
     6901 cgattcgcgt tgtatcgaag cgttttcgca acatcagtaa aaacatgcag aacaccatgg
     6961 ggcaggtgac caccagcgca gaacaaatgc tgaagggcca caaagaagta ttgattttcg
     7021 gtggtcagga agtggaaacg aaacgctttg ataaagtcag caaccgaatg cgtcttcagg
     7081 ggatgaaaat ggtttcagcc tcttccatct ctgatccgat cattcagctg atcgcctctt
     7141 tggcgctggc gtttgttctg tatgcggcga gcttcccaag tgtcatggat agcctgactg
     7201 ccggtacgat taccgttgtt ttctcttcaa tgattgcact gatgcgtccg ctgaaatcgc
     7261 tgaccaacgt taacgcccag ttccagcgcg gtatggcggc ttgtcagacg ctgtttacca
     7321 ttctggacag tgagcaggag aaagatgaag gtaagcgcgt gatcgagcgt gcgactggcg
     7381 acgtggaatt ccgcaatgtc acctttactt atccgggacg tgacgtacct gcattgcgta
     7441 acatcaacct gaaaattccg gcagggaaga cggttgctct ggttggacgc tctggttcgg
     7501 gtaaatcaac catcgccagc ctgatcacgc gtttttacga tattgatgaa ggcgaaatcc
     7561 tgatggatgg tcacgatctg cgcgagtata ccctggcgtc gttacgtaac caggttgctc
     7621 tggtgtcgca gaatgtccat ctgtttaacg atacggttgc taacaacatt gcttacgcac
     7681 ggactgaaca gtacagccgt gagcaaattg aagaagcggc gcgtatggcc tacgccatgg
     7741 acttcatcaa taagatggat aacggtctcg atacagtgat tggtgaaaac ggcgtgctgc
     7801 tctctggcgg tcagcgtcag cgtattgcta tcgctcgagc cttgttgcgt gatagcccga
     7861 ttctgattct ggacgaagct acctcggctc tggataccga atccgaacgt gcgattcagg
     7921 cggcactgga tgagttgcag aaaaaccgta cctctctggt gattgcccac cgcttgtcta
     7981 ccattgaaaa ggcagacgaa atcgtggtcg tcgaggatgg tgtcattgtg gaacgcggta
     8041 cgcataacga tttgcttgag caccgcggcg tttacgcgca acttcacaaa atgcagtttg
     8101 gccaatgatc gaaaaaatct ggtctggtga atcccctttg tggcggctat tgctgccact
     8161 ctcctggttg tatggcctgg tgagtggcgt gatccgtctt tgctataaac taaaactgaa
     8221 gcgcgcctgg cgtgcccccg taccggttgt cgtggttggt aatctcaccg caggcggcaa
     8281 cggaaaaacc ccggtcgttg tctggctggt ggaacagttg caacagcgcg gtattcgcgt
     8341 gggggtcgta tcgcggggat atggtggtaa ggctgaatct tatccgctgt tattgtcggc
     8401 agataccaca acagcacagg cgggtgatga acctgtgttg atttatcaac gcactgatgc
     8461 gcctgttgcg gtttctcccg ttcgttctga tgcggtaaaa gccattctgg cgcaacaccc
     8521 tgatgtgcag atcatcgtaa ccgacgacgg tttacagcat taccgtctgg cgcgtgatgt
     8581 ggaaattgtc gttattgatg gtgtgcgtcg ctttggcaat ggctggtggt tgccggcggg
     8641 gccaatgcgt gagcgagcgg ggcgcttaaa gtcggttgat gcggtaatcg tcaacggcgg
     8701 tgtccctcgc agcggtgaaa tccccatgca tctgctgccg ggtcaggcgg tgaatttacg
     8761 taccggtacg cgttgtgacg ttgctcagct tgaacatgta gtggcgatgg cggggattgg
     8821 gcatccgccg cgcttttttg ccacgctgaa gatgtgtggc gtacaaccgg aaaaatgtgt
     8881 accgctggcc gatcatcagt ctttgaacca tgcggatgtc agtgcgttgg taagcgccgg
     8941 gcaaacgctg gtaatgactg aaaaagatgc ggtgaaatgc cgggcctttg cagaagaaaa
     9001 ttggtggtat ttgcctgtag acgcacagct ttcaggtgat gaaccagcga aactgcttac
     9061 gcaactaacc ttgctggctt ctggcaacta gttacgccgc ggcagcgttc gattgatgga
     9121 gtcatgaatg tcgctgccgc acctctccct tgctgatgcg cgtaatcttc accttgccgc
     9181 acaaggcctg ttaaacaaac cccgccgtcg agcgtcgttg gaggatattc cggcaacgat
     9241 ctcccgcatg tccttgctgc aaatcgatac catcaatatt gttgcccgta gtccatatct
     9301 ggtgcttttc agtcgtctgg gaaattatcc tgcccagtgg ctggatgagt ctctggcgcg
     9361 tggcgaatta atggaatact gggcgcatga agcctgcttt atgccgcgta gcgactttcg
     9421 tcttattcgc caccgcatgc tggcacctga aaaaatgggc tggaaataca aagacgcctg
     9481 gatgcaggaa catgaggcgg aaattgcaca gttaattcag catattcatg ataaggggcc
     9541 ggtacgttca gccgattttg agcatcctcg taaaggtgca agcggctggt gggaatggaa
     9601 gccgcataaa cggcatctgg aaggtttatt tactgccgga aaggtgatgg tgattgaacg
     9661 gcgcaacttc cagcgcgttt atgatttaac ccaccgtgtc atgcctgact gggatgatga
     9721 gcgcgatctc gtttcgcaaa cagaagcaga aatcatcatg ctggataaca gtgcgcgtag
     9781 cctgggaata ttccgcgaac agtggctggc agattactat cggctgaaac gtccggcact
     9841 ggcggcgtgg cgcgaagcga gggctgaaca gcagcaaatc attgctgtgc atgttgaaaa
     9901 attgggcaat ctttggctgc atgatgattt gctgccgcta ctcgagcgag cgctggccgg
     9961 aaagctcact gcaacgcaca gcgcggtact ttcgcctttt gatcctgttg tctgggatcg
    10021 caaacgcgca gagcagcttt ttgattttag ctaccggctg gagtgctata ccccggcgcc
    10081 gaaacgccag tatggctatt ttgttctgcc gttattacat cgtgggcaat tagttgggcg
    10141 aatggatgcc aaaatgcatc gccagacagg catccttgaa gttatctctc tgtggttaca
    10201 ggaaggtatt aaaccaacga caacgctgca aaaagggcta cgtcaggcga ttactgattt
    10261 cgctaactgg cagcaggcaa cgcgggtgac attaggatgc tgcccgcaag gcctctttac
    10321 tgattgccgc accggctggg aaatagaccc cgtcgcataa atgattatga taagatttat
    10381 gcattcataa cccgatccat ctggaggaac tatggatcat cgtctgcttg aaatcattgc
    10441 ctgcccggtt tgcaacggaa aactttggta taaccaggaa aaacaagagc ttatttgcaa
    10501 actggacaac ctcgctttcc cgctgcgtga tggcattcca gtgttgctgg aaacggaagc
    10561 ccgcgtgctg actgctgatg agagtaaatc atgagttttg tggtcattat tcccgcgcgc
    10621 tacgcgtcca cgcgtctgcc cggtaaacca ttggttgata ttaacggcaa acccatgatt
    10681 gttcatgttc ttgaacgcgc gcgtgaatca ggtgccgagc gcatcatcgt ggcaaccgat
    10741 catgaggatg ttgcccgcgc cgttgaagcc gctggcggtg aagtatgtat gacgagcgcc
    10801 gatcatcagt caggaacaga acgtctggcg gaagttgtcg aaaaatgcgc attcagcgac
    10861 gacacggtga tcgttaatgt gcagggtgat gaaccgatga tccctgcgac aatcattcgt
    10921 caggttgctg ataacctcgc tcagcgtcag gtgggtatgg cgactctggc ggtgccaatc
    10981 cacaatgcgg aagaagcgtt taacccgaat gcggtgaaag tggttctcga cgctgaaggg
    11041 tatgcactgt acttctctcg cgccaccatt ccttgggatc gtgatcgttt tgcagaaggc
    11101 cttgaaaccg ttggcgataa cttcctgcgt catcttggta tttatggcta ccgtgcaggc
    11161 tttatccgtc gttacgtcaa ctggcagcca agtccgttag aacacatcga aatgttagag
    11221 cagcttcgtg ttctgtggta cggcgaaaaa atccatgttg ctgttgctca ggaagttcct
    11281 ggcacaggtg tggatacccc tgaagatctt gagcgcgttc gcgctgaaat gcgctaattt
    11341 cacttcacga cacttcagcc aattttggga ggagtgtcgt accgttacga ttttcctcaa
    11401 tttttctttt caacaattga tctcattcag gtgacatctt ttatattggc gctcattatg
    11461 aaagcagtag cttttatgag ggtaatctga atggaacagc tgcgtgccga attaagccat
    11521 ttactgggcg aaaaactcag tcgtattgag tgcgtcaatg aaaaagcgga tacggcgttg
    11581 tgggctttgt atgacagcca gggaaaccca atgccgttaa tggtaagaag ctttagtacg
    11641 cccggaaaag cccgacaact ggcatggaaa accaccatgc tggcaagaag tgggactgtc
    11701 cgtatgccga ctatttatgg tgtgatgacg catgaagaac accccggccc cgatgtcctg
    11761 ctactggagc ggatgcgtgg tgtttcggtg gaggcaccag cccgaacacc agaacgctgg
    11821 gaacaactca aagaccaaat cgttgaagcc ttactggcct ggcaccgtca ggacagtcgc
    11881 ggttgcgtcg gcgcggtcga caatactcag gaaaatttct ggccctcatg gtaccggcaa
    11941 catgttgaag tgctatggac cacgctcaat cagttcaata acaccggtct gacgatgcag
    12001 gataagcgga tcctgtttcg cactcgcgaa tgtctcccgg cattatttga aggctttaac
    12061 gacaattgtg tgctgattca cggtaacttc tgtttacgca gcatgttgaa agattcgcgc
    12121 agcgatcagt tactggcgat ggtcgggccg ggactaatgc tttgggcacc gcgagaatac
    12181 gaactgttcc gactaatgga taattctctg gcggaagatt tgctctggag ttacctgcaa
    12241 cgcgcgccag tggcggagtc gttcatctgg cggcgttggt tgtatgtgtt atgggatgaa
    12301 gttgcgcaac tggttaatac cggacgattt agtcggcgca acttcgatct ggcatcaaaa
    12361 tcactcttgc cgtggctcgc ctgacgaacc ttttagccac tgccagatac ggccaagcgt
    12421 ttcatagcca acacgatcgc tatgcatcaa ccagaccgga gaagggattg cccgttccca
    12481 cgggttaagc ggcgagtcga tggccaactg attcgccggg gctggtagcg gatttaaccc
    12541 ttcctgctga aaaaagatca tcgcccgcgg cagatgtgat gcggaggtca ccagcaggaa
    12601 aggggcgtca ccaatcgcct gtttcactgc tgcagcttct tcttcggtat cttttggcaa
    12661 atccagggtg ataatttgct cgcgcggcac gcccagcgat tgcgcaactc tggcacctac
    12721 ttccgctgta ctcaccgtat tggtttttgc tacgcctccc gtgaagatca gttttgatcc
    12781 cggattttcg cgccataagc gaataccttc attcaggcgt ggcagactgt tattgattaa
    12841 attagagctc ggtgcccact gcgggttcca ggtataacca cctccgagca ccacgatata
    12901 gtccactttt tgcgaattat tccatgtcgg ataggtgctt tcgatgggac gcagcaggcg
    12961 gtcggctacc ggttgcaaac tcaataacaa gagcgccagc cacccaatgc taataaaaat
    13021 cttcccggtt ttttgaaaac ggctaaacca cagcagcgcc aggccagcgc caataatcaa
    13081 caacatcagc ggaagtggca gcaacatatt gccaatcact tttttcagtg taaaaagcat
    13141 cctttctggt tcctttttta accatatagc aagggatcgc cagcgatatt acaccagacg
    13201 ggttcattct cgccgtggct gtgacaaaat agcgtcttta tcagaaaacg tcttagccaa
    13261 ccggtggaga aagcaatgca ggatcgcaat tttgatgata ttgcggaaaa gttttcccgt
    13321 aacatttacg gcaccaccaa agggcagctt cgacaggcta ttctgtggca ggatctcgat
    13381 cgcgtgctgg cggaaatggg cccgcaaaaa ctgcgtgtgc tggatgctgg cggtggagaa
    13441 gggcagaccg caatcaaaat ggccgagcgt gggcatcagg tcattttatg cgatctttct
    13501 gcgcagatga tcgaccgcgc aaaacaggcg gcagaagcaa aaggtgtgag cgacaacatg
    13561 caatttatac attgcgccgc tcaggatgtt gcttcgcatt tggaaacgcc cgttgatctg
    13621 atattgttcc atgcggtgct cgagtgggtg gctgatcccc gcagcgtatt gcagaccctc
    13681 tggtcagtgt tgcgtccagg cggcgtgttg tcgttaatgt tctacaatgc gcatggtttg
    13741 ttgatgcata acatggtcgc cgggaatttt gattacgtgc aggcgggaat gccgaaaaag
    13801 aaaaaacgga cgctttcgcc agattatcca cgcgacccgg cgcaggttta tctgtggctg
    13861 gaagaagctg gttggcaaat tatgggtaag acaggcgttc gcgtgtttca tgattatctg
    13921 cgcgagaaac accagcagcg cgactgctat gaagcattac ttgaattaga aacgcgttat
    13981 tgccgtcagg aaccgtatat taccctgggg cgttatattc atgtcaccgc gcgcaaaccg
    14041 cagagcaagg ataaagtatg agtgaatttt cccagacagt ccccgaactg gttgcctggg
    14101 ccagaaaaaa tgacttctcc atctcgctgc cggtagaccg actctctttt ctgctggcgg
    14161 ttgccacgct gaacggcgag cgtctggatg gtgagatgag tgaaggcgag ctggtggatg
    14221 cattccgcca tgtgagtgat gcgtttgagc aaaccagcga aaccatcggc gtgcgcgcca
    14281 ataacgcgat caacgacatg gtgcgtcaac gtctgctgaa ccgctttacc agcgagcagg
    14341 cggaagggaa cgcaatttac cgtctgacgc cgctcggcat cggcattact gactactaca
    14401 tccgtcagcg cgagttttct acgctgcgtc tttctatgca gttgtcgatt gtggcgggtg
    14461 agctcaaacg cgcagcagat gccgccgaag agggcggtga tgaatttcac tggcaccgta
    14521 atgtctatgc gccactgaaa tattcggtag cagaaatttt cgacagtatc gacctgacgc
    14581 aacgtctgat ggacgaacag cagcagcagg tgaaggacga tatcgcccag ttgctgaaca
    14641 aagactggcg ggcggcgatt tccagctgtg aattgttgct ttcggaaact tccggaacgc
    14701 tgcgtgaatt gcaggatacg ctggaagcgg caggcgacaa attgcaggct aatctgttgc
    14761 gcattcagga tgcgacgatg acccatgacg atctgcgttt cgtcgatcgt ctggtgttcg
    14821 atctgcagag caaactcgat cgtattatca gttggggcca gcaatccatc gacttgtgga
    14881 ttggctacga ccgccacgta cacaaattta ttcgtaccgc gatcgatatg gataaaaacc
    14941 gcgtctttgc tcagcggtta cgtcagtcgg tacaaaccta ttttgatgag ccgtgggcgc
    15001 taacttatgc caatgccgat cgtctgctgg atatgcgtga cgaagagatg gcactgcgcg
    15061 atgaagaagt gactggggaa cttcctgagg atctggaata cgaagagttt aacgagatcc
    15121 gcgaacagct ggcggcgatc atcgaagaac aacttgccgt gtacaaaacc agacaagtgc
    15181 cgctggatct tggtctggtg gtacgcgaat atctgtcaca gtatccgcgt gcacgtcact
    15241 ttgacgttgc gcgtattgtt attgatcagg cggtacgtct tggcgtagcg caagcagatt
    15301 tcaccggact gccagcgaaa tggcagccga ttaatgatta cggagccaag gtacaggcgc
    15361 atgtcatcga caaatattga acaagtgatg ccggttaagc tggcgcaggc gctggcgaat
    15421 ccgttatttc cggcgctgga cagcgcctta cgttcaggac gccatattgg cctcgacgaa
    15481 ctggataatc atgcattcct gatggatttt caggaatatc tggaagagtt ttacgcgcgt
    15541 tataacgttg agcttattcg cgcaccagaa gggttcttct atttacgccc acgttccacc
    15601 acgctgatcc ctcgttccgt cttgtcggaa ctggatatga tggtcgggaa aatcctctgt
    15661 tatctctatc tcagcccgga acggctggcg aatgagggga ttttcaccca gcaggaactg
    15721 tacgacgaac tgctcaccct ggccgatgaa gcaaaactgc tgaaactggt gaacaaccgt
    15781 tcaaccggtt cagacgttga ccgtcagaag ttgcaggaga aagtacgttc ttcgctcaac
    15841 cgtctgcgtc gtttaggcat ggtgtggttt atgggccacg acagcagcaa gtttcgcatt
    15901 accgaatcgg tgttccgctt cggagccgat gtgcgtgctg gcgacgatcc ccgtgaagca
    15961 cagcgtcgcc tgattcgtga tggcgaagca atgccgattg aaaatcatct gcaactcaac
    16021 gatgaaaccg aagagaatca gccagatagc ggagaggaag aataatgatt gaacgcggta
    16081 aatttcgctc actgacgctg attaactgga acggcttttt tgcccgaact tttgaccttg
    16141 acgagctggt cacgacgctt tctggcggta acggggcggg taaatccacc accatggcgg
    16201 cgttcgttac ggcgctgatc cccgacctga ccctgctgca tttccgtaac actacggaag
    16261 ccggggccac cagcggttcg cgcgataaag gtctgcacgg taagctgaaa gcgggtgtct
    16321 gttattcgat gctcgacacc attaactcgc gccaccagcg cgtggtggtc ggtgtgcgtc
    16381 tgcaacaggt tgccggacgc gatcgtaaag tggatatcaa gccgtttgcc attcagggac
    16441 tgccgatgtc ggtgcagccg acacagctgg tgaccgaaac cctgaacgaa cgccaggcgc
    16501 gcgtgctgcc gcttaacgag ctgaaagaca agctcgaggc gatggaaggc gtgcagttta
    16561 aacagttcaa ctccattact gattaccact cgctgatgtt cgatctgggc atcatcgcgc
    16621 gtcgtctgcg ctccgcatct gaccgtagca aattctatcg tctgatcgaa gcttcgctgt
    16681 atggcgggat ctccagtgcc attacccgtt ctctgcgcga ctacctgttg ccagaaaaca
    16741 gcggcgtgcg taaagcgttc caggacatgg aagcggcgct gcgtgaaaac cgtatgacgc
    16801 tggaagcgat tcgtgtcacc cagtcggacc gcgacctgtt taagcatctg atcagcgaag
    16861 ccaccaacta cgtggcggcg gactacatgc gtcacgccaa cgagcgccgt gtccatctcg
    16921 acaaagccct ggagtttcgt cgcgagctac atacttcgcg tcagcaactg gcggctgagc
    16981 agtacaaaca cgtcgatatg gcgcgtgagc tggcagagca caacggtgcc gaaggcgatc
    17041 tggaagcgga ttatcaggcg gccagtgatc acctgaacct ggtgcaaacc gcactgcgtc
    17101 agcaggagaa gatcgaacgc tacgaagcgg atctcgatga gctgcagatc cgtctggaag
    17161 agcaaaatga agtggtggca gaagccatcg aacgccagga agagaatgag gctcgtgcgg
    17221 aagctgccga actggaagtg gacgagctga aaagccagct tgctgactac cagcaggcgc
    17281 tggacgtcca gcaaacgcgc gcgatccagt ataaccaggc gattgctgcg cttaatcgtg
    17341 ccaaagaact gtgccatctg ccggacttaa ccgccgactg cgccgccgaa tggctggaaa
    17401 ccttccaggc gaaagagctg gaagcgactg aaaaaatgct ctctcttgag cagaaaatga
    17461 gcatggcgca aaccgcgcac agccagtttg agcaggctta tcagctggtg gtggcaatca
    17521 acggcccact ggcgcgtaac gaggcgtggg atgtcgctcg cgaactattg cgcgaagggg
    17581 tcgatcagcg tcacctggca gagcaggttc agccgctgcg gatgcgatta agcgaactgg
    17641 aacagcgtct acgcgagcag caagaagctg agcgtctgct ggcagatttc tgcaaacgtc
    17701 agggcaagaa ttttgatatc gacgaactgg aagccctgca tcaggaactg gaagcacgca
    17761 ttgcctctct ttccgatagc gtgtctaacg cccgtgaaga gcgcatggca ctgtgccagg
    17821 agcaggaaca gctgcagtct cgcattcaga gtttgatgca gcgtgcgccg gtttggctgg
    17881 cagcgcaaaa cagtctcaac cagttgagcg aacagtgcgg cgaagagttt acctccagcc
    17941 aggacgtcac cgaatatctg caacagttgc tggagcgtga gcgagaggcg attgttgaac
    18001 gcgatgaagt gggcgcgcgc aaaaacgccg tcgatgaaga gatcgaacgt ttaagccagc
    18061 ctggcggctc tgaagatcag cgtctgaacg cgctggcgga gcgttttggt ggtgtgctgc
    18121 tgtcagaaat ttatgacgac gttagcctgg aagatgcgcc gtacttctca gcgctgtatg
    18181 gcccgtcacg ccacgccatc gtggtgccag atctgtcaca ggtaactgaa cacctggaag
    18241 gcttgaccga ttgcccggaa gatctctatc tgatcgaagg agatccgcag tcattcgatg
    18301 acagcgtgtt cagcgttgat gagctggaaa aagcggtagt ggtgaaaatc gccgatcgtc
    18361 agtggcgtta ttcacgtttc ccggaagtgc cgctgtttgg tcgtgctgcg cgtgaaagcc
    18421 gtattgaaag cctccatgcc gagcgtgaag tgctttccga acgcttcgcc acgctctcct
    18481 ttgatgtaca gaaaactcag cgtctgcatc aggcgttcag ccgctttatc ggcagtcatc
    18541 tggcggttgc gtttgagtct gacccggaag cagaaatccg tcaactgaac agccgtcgcg
    18601 tcgaactgga gcgggcgtta agtaatcatg aaaatgataa ccagcagcag cgtattcagt
    18661 ttgagcaggc gaaagagggc gttacggcgc tgaaccgcat tctgccgcgt ctcaacctgt
    18721 tggctgatga cagcctggcg gatcgcgtcg atgaaatccg cgaacgtctg gatgaagccc
    18781 aggaagccgc gcgttttgtt cagcagtttg gcaatcaact ggcgaaactg gaaccgattg
    18841 tttcggtatt gcagagcgac ccggaacagt tcgaacagtt aaaagaagat tacgcgtact
    18901 ctcagcagat gcagcgcgat gcccgtcagc aggcgtttgc cctgacggaa gtggtgcagc
    18961 gtcgtgcgca ctttagctat tctgactcgg cagaaatgct tagcggtaac agcgatctca
    19021 acgaaaaact gcgtgaacgt ctggaacagg cggaagcgga gcgtacccgc gctcgcgaag
    19081 cgttgcgcgg tcacgcagcg cagttgagtc agtacaacca ggtgctggct tcgctgaaaa
    19141 gttcttacga caccaaaaaa gagctactca acgatctgca acgtgaattg caggatatcg
    19201 gcgtgcgtgc tgatagcggg gcagaagagc gggcgcgtat tcgccgtgac gagctgcatg
    19261 cgcaactgag caataaccgt tcacgccgca atcaactgga aaaagcgctt accttctgcg
    19321 aagcggagat ggacaacctg acccgcaaac tgcgcaagct ggagcgggat tactttgaga
    19381 tgcgcgagca ggtagtgacc gccaaagcgg gctggtgtgc ggtgatgcgc atggtgaaag
    19441 ataacggcgt tgagcgccgc ttacaccgtc gtgagctggc ttatctctcc gctgatgatt
    19501 tgcgttccat gtcggataag gcgttaggtg cgctgcgtct ggcggtggcg gataacgaac
    19561 atctgcgcga cgtgctgcgc atgtcggaag atccgaaacg tccggagcgt aaaattcagt
    19621 tcttcgtggc ggtttatcag catctgcgtg aacgtattcg tcaggatatt attcgtaccg
    19681 atgatccggt ggaagctatc gaacagatgg agattgaact tagccgtctg accgaagaat
    19741 taacctcccg tgaacagaaa ctggcgatca gttcccgcag cgtggcgaac atcattcgca
    19801 aaaccattca gcgcgagcag aaccgtatcc gtatgctcaa ccaggggttg cagaacgtat
    19861 cgtttggtca ggtgaacagc gtgcgtctca acgtgaacgt gcgtgaaacg cacgccatgc
    19921 tactggatgt gctctctgaa cagcacgagc agcatcagga tctgtttaac agcaaccgtt
    19981 tgaccttctc ggaagcgctg gcgaaactgt atcaacgtct taacccgcag attgatatgg
    20041 ggcagcgcac gccgcagacc atcggtgaag aactgctgga ttaccgcaac tatctggaaa
    20101 tggaagttga ggttaaccgt ggttccgatg gctggctgcg cgcagagtct ggtgcattgt
    20161 cgaccggtga ggcgattggt accggtatgt cgattctggt gatggtggta caaagctggg
    20221 aagatgaatc tcgccgcctg cgcggtaaag atatctctcc ttgccgcctg ctgttcctcg
    20281 atgaagcagc gcgactggat gctcgttcta tcgccacgct gtttgaattg tgtgagcgtt
    20341 tgcaaatgca actcatcatc gcagcgccgg aaaatatcag cccggagaaa ggcaccacct
    20401 ataaactggt gcgtaaagtc ttccagaata ccgaacacgt tcatgtcgtc ggcctgcgag
    20461 gatttgcgcc gcaactccct gaaacgcttc caggaactga cgaagcgcct tctcaggcga
    20521 gttaaaatta aggcggcagc aatgccgcct tttctttttc cgaaaactcc gtttctgcac
    20581 taaaaaagtg gcacattacg gcgcgctttt ctttaaactt ctttacatta ggttatgtaa
    20641 aaacgtatcg gcgtttatat actgaagata agcctgatga gtaacaggct tgctcgtcat
    20701 actttcgtga gtattggcgt tgtacaggca agtcgtaaaa taacagcctg gctattcaga
    20761 gtatgataaa aacagggggc aagggatgtt gcttaatatg atgtgtggtc gtcggctgtc
    20821 ggcaatcagt ttgtgcctgg ccgtaacatt cgctccactg ttcaatgcgc aggccgatga
    20881 gcctgaagta atccctggcg acagcccggt ggctgtcagt gaacagggcg aggcactgcc
    20941 gcaggcgcaa gccacggcaa taatggcggg gatccagcca ttgcctgaag gtgcggcaga
    21001 aaaagcccgc acgcaaatcg aatctcaatt acccgcaggt tacaagccgg tttatcttaa
    21061 ccagcttcaa ctgttgtatg ccgcacgcga tatgcaaccc atgtgggaaa accgtgatgc
    21121 tgttaaagcc ttccagcaac agctggcaga ggtggcgatt gccggtttcc agccgcagtt
    21181 taataaatgg gtagagttac tgaccgatcc tggtgttaac gggatggcac gcgacgtggt
    21241 gctctctgat gcgatgatgg gctatctcca tttcattgca aatattccgg tcaaaggcac
    21301 tcgctggcta tatagcagta aaccttatgc acttgcaacg ccgccgctct cggtgattaa
    21361 ccaatggcag ctggcgctgg ataaaggtca attgcctacg tttgttgcag gactggcacc
    21421 gcagcatccg caatatgcgg cgatgcatga atcgttactg gccttactct gtgacaccaa
    21481 accgtggccc caactgaccg gcaaagcaac gttgcgccca gggcagtgga gtaacgacgt
    21541 accggcgttg cgcgaaatat tgcaacgcac aggcatgttg gacggggggc cgaaaattac
    21601 tctacctggc gatgacacgc caactgacgc ggtagtcagc ccatccgctg ttactgttga
    21661 aacagcagaa actaagccga tggataagca aacgacgtct cgtagtaaac ctgcgcctgc
    21721 cgttcgcgcc gcctacgata atgaactggt ggaagccgtt aaacgttttc aggcatggca
    21781 aggattgggg gcagatggtg ctattggccc ggcaacacgt gactggttaa acgtaacgcc
    21841 cgcccagcgt gctggcgtgt tggctctcaa catccagcga ttgcgcttgc tgccaacaga
    21901 gctttctacc gggatcatgg ttaacattcc ggcctattcg ctggtctact atcagaacgg
    21961 caatcaggtg ctggattcgc gagtcattgt cggtcgcccc gatcgcaaaa cgccgatgat
    22021 gagcagtgcc cttaacaacg tagtggtaaa cccgccgtgg aacgtacctc caactctggc
    22081 acgcaaagat attctgccaa aagtgcgcaa cgatccggga tatctcgaaa gccatggcta
    22141 tacggtgatg cgcggctgga acagcagaga agcgattgac ccatggcagg ttgactggtc
    22201 tacaatcacg gcctcgaatt taccgttccg cttccagcag gctccaggcc cacggaactc
    22261 gctggggcgc tataaattca atatgccgag ttcagaggcc atttatttgc atgacacgcc
    22321 gaaccacaat ctgttcaagc gtgatacacg cgcattgagc tcaggctgtg tacgagtgaa
    22381 taaagcttcc gatctggcga atatgctgtt gcaggatgca ggctggaatg acaaacgtat
    22441 ttctgatgcg ctgaagcagg gtgatacacg ttacgtcaat attcggcagt cgattccggt
    22501 gaatctctac tacctgacgg cctttgttgg tgcagatggt cgtacccagt atcgtacaga
    22561 tatttacaat tatgatctgc ctgcgcgatc cagctcgcaa atcgtatcga aagcggaaca
    22621 attaatcagg taaatgaagt agttcgggga aatcagttgt cgtaataatt agcatgattg
    22681 ggggcgattc tctgcagccc ccgtcactgc tggggttgag tcatcttgac gtctgcttta
    22741 cgggcggtta aggtgcctct tgtgcgccag aagtgcatat aaacgataac attgacctgt
    22801 agacttgatt atcatggaca aattcgacgc taatcgccgc aaattgctgg cgcttggtgg
    22861 cgttgcactc ggtgccgcca tcctgccgac ccctgcgttt gcaacactct ctaccccacg
    22921 cccgcgcatt ttgacactca ataatcttca taccggagag tcaatcaaag cggagttttt
    22981 cgatggcaga ggctatattc aggaagaatt ggcaaaactt aaccattttt tccgcgatta
    23041 ccgcgcgaac aaaataaagt ccatcgaccc aggattattc gaccagttgt atcgcctgca
    23101 agggttgtta ggcacgcgca aaccggtgca actcatttcc ggttatcgtt ctattgatac
    23161 caacaatgaa ctacgcgccc gcagccgtgg agtagcgaag aaaagctatc acactaaagg
    23221 ccaggcgatg gatttccata ttgaaggtat cgcgttaagc aatattcgca aagccgcgtt
    23281 atctatgcgc gcaggtggtg taggatatta tccacgtagt aactttgtgc atattgatac
    23341 cgggccagca cggcactggt agtaattgct taacgaaaca ggggcagtat gaactatcgt
    23401 attattccgg tcaccgcatt ctcccagaac tgttcattaa tctggtgtga acaaacccgt
    23461 ctggccgcac tggtcgatcc tggcggcgat gcggaaaaaa tcaaacagga agttgatgac
    23521 agcggcctga cactgatgca gatcctgctg acgcatggtc atctggacca cgttggcgca
    23581 gcggcggaac tggcgcaaca ttacggcgtg ccggttttcg gcccggaaaa agaagatgag
    23641 ttctggctgc aaggcttgcc tgcgcaaagt cgtatgtttg gtctggaaga gtgccagccg
    23701 ctgacgccag atcgttggct gaacgaaggc gataccatca gcatagggaa tgtgacttta
    23761 caggtgttac attgccctgg gcatacgccg ggtcatgtcg tgttttttga tgatcgggca
    23821 aagctgctga tttctggcga tgttattttc aaaggcggag tagggcgcag tgacttcccg
    23881 cgtggcgatc ataatcaact gatttcttca atcaaagata aattgctgcc actgggggat
    23941 gacgtgatat ttattccggg tcacggacca ttatccacac ttggttatga acgcctgcat
    24001 aatcccttcc tgcaagacga aatgcccgtc tggtaaggca cataaaaaag cccgctttta
    24061 atgcgggcct ggatttctgg caaagtgcgc tttgtttatg ccggatgcgg cacgagcgcc
    24121 ttatccggcc tacaaaatcg tgcaaattca aaatattgca ggggacgcgt aggcctgata
    24181 agcgtagcgc atcaggcaat gttgcgtttg tcatcagtct cagcccgctt ttcagcgggc
    24241 ttcattgttt ttaatgctta cagcactgcc acaatcgctt cgcacagcgg agccatgtta
    24301 tctggtgtca tcccggccac atttacgcga ccagaagcaa ccgcatatac gccaaactct
    24361 tcgcgcagac gcagcacttg ttcttttgtc aggccactga aggagaacat gccgttctgt
    24421 ttgatgataa agctgaagtc gcggtttgcg cctttttcct gcagcgtatt gacgaacaac
    24481 tgacgcatac gctgaatacg ctggcgcata tcagtcagct cttgttccca aatcgcacgt
    24541 aacgcatcgt tgctcaggat ggtggcaaca acagaagcgc cgtgtgctgg tgggttagag
    24601 tagttagcgc gaatcgccgc tttcatttgg ctgaatgcgc gatcaacggt ttcactgtcg
    24661 gcagcaacca gagtacaagc gccaacacgc tcgttgtaca ggccaaagtt tttagagtag
    24721 gaactggcaa caatcagctc tttatgcata gccgcgaaag cgcgcagtcc ttcagcatct
    24781 tcttccagac cacgggcaaa accctggtaa gcgaagtcaa acagcggtaa ccagcctttc
    24841 tcaacggaga gttgtgccag tgtttgccat tgttccagcg tagggtcgat accggttggg
    24901 ttatggcagc agccatggaa cagcactacg tcgccagcct gagcttcatt caggctgtta
    24961 atcagtgcat cgaagtcaag agtgtgattt tccgcatcat aataagcgta ttcacgaact
    25021 tccagacctg cagagttaaa gacgctctta tggttcggcc agcttgggtt gctcacccac
    25081 acacgcttaa cgctggtatt ttttgccagg aaatcggcag ccacgcgtag tgcgccagtg
    25141 ccccccggag tctgtgccgt gcgagcacgt ttgtcattga tcagggcgct acctttacca
    25201 aacagcagtt cctgagtgca gcgaccaaat tcagggatgc cgtcaatgcc gaggtaattt
    25261 ttggtggttt cattttcgag cagatactgt tcagcctttt tcacgctggt cagtaccggg
    25321 gttttgcccg tctcatcttt atagacacca atcccgaggt taattttgcc gggacgttca
    25381 tcggcacgaa acagatcggc caggcccaga atcgggtcgg caggagcggc ggtaatgttc
    25441 tcaaacatga cgaggttcca ttatggttac agaagggaag tccgctatca gggtaacggg
    25501 agatttacaa aattccaact attactgatg aaaacgcagg ctgtttttgc aagacgtgag
    25561 attgctctgg aaggtataaa aaaaacagga ccaaagtcct gttttttcgg catttaacaa
    25621 agaggtgtgc tattagaact ggtaaacgat acccacagca acggtgtcgt ctgaacctac
    25681 gcccagtttg ttgtcagaat cgatctggtt gatgatgtag tcaacatagg tggacatgtt
    25741 tttgttgaag tagtaggttg cgcccacttc aaagtagttc accagatcaa catcaccgat
    25801 accttctacg tctttcgctt tagatttggt gtaagcgatg gacggacgca gaccgaaatc
    25861 gaactggtat tgcgcaacta acagaacgtc ttgcgttttg ttggcgaagc cgctggtgtt
    25921 tgtaaattta ttagtgatcg gcgtagcgtt acgggtttca ccgtagttcg ctgccaggta
    25981 gatgttgttc gcgtcgtact tcagaccagt agcccactgt tcagcttttt taccgttgcc
    26041 aagaggttga gcttcttgca ggttggtacg gtcagctgca ccataagcac caacgatacc
    26101 aaagccttcg tattcgtagc tgatagaacc gccaacaccg tcgccgttag aacggcgtgc
    26161 agtgtcacgc tcgtttttac ccaggtactg aacagcgaag ttcaggccat caaccagacc
    26221 aaagaagttg gagttacgat aggtagcaac gccgccaaca cgaccaacga agaagtcatc
    26281 gctgtatgca gtatcaccac caaattctgg cagcatatcg gtgtaaccca gtgcatcata
    26341 aaccacaccg tagttacggc cgtaatcgaa agaaccaacg tcagcgtatt taagacccgc
    26401 gaatgccaga cgcgttttgt taccagtttg agcgtcagcg ccttcagagt tgttaccctg
    26461 gaagttatat tcccactgac cataaccggt cagatcggaa ttgatttgag tttccccttt
    26521 aaaaccaaga cgggcatagg tcatgtcgcc attgccaccg taactgtttt caccgttacc
    26581 cttggaaaaa taatgcagac caacagcttt accgtacaga tctactttgt tgccatcttt
    26641 gttatagatt tctgcagcgt ttgcagtacc tgctactaac agagcaggga cgatcactgc
    26701 cagaatattg cgcttcatca ttatttatta ccctcatggt tttttttatg acacctgcca
    26761 ctgccgtcaa taagttctgt caataaaaat ttacggaact attgatgaga gtttggtgtc
    26821 tttatgtgtc tgcaggcatc tttccattca aactaacgtt tcgctaccgt gaaagtgcta
    26881 caaagataaa gatttggttt caaaaagaaa aaatatgtaa ccaaaagtaa aatttaagga
    26941 actttgtgaa caccgtcata tttccataga gacgtgatga tatttacagc aattttaatc
    27001 tatttatatg atttccttat atttaaatta actaaacgga aattttgttt ctgatggaaa
    27061 ctttatcgac ctggcacaaa atcttctttc agacatccag aatgccaaaa aatagtatga
    27121 aaattgtgct attagctaag aaaaaactaa tccgcaataa gaatgcggat tagtttttgc
    27181 gcgtaaatgt tgcaatgtaa tattccgtaa caggatgatc gttatggcgg ggttgcaaat
    27241 agattgcttg acttaacaaa cagataactt gacagaaaag ataaaaaaag agccagcggg
    27301 cgctggctct tgaagacgct aaattagaag ctggcgttac gcggagtacg tgggaacgga
    27361 atcacatcac gtacgttttg cacgccagtt acgtaagcaa tcagacgttc aaaaccaaga
    27421 ccgaaacctg aatgcggaac agtaccgtag cgacgcagat cgcgatacca ccagtaatct
    27481 tctttattca ggcccatttc cagcatacgc tcgtccagca cgtccagacg ttcttcacgc
    27541 tgggagccac caatgatctc accgatgccc ggagccagaa cgtccatagc cgcaacggtt
    27601 ttaccgtctt cgttaaggcg catatagaac gctttaatat ctttcggata gtttttaacc
    27661 actaccggtg ctttaaagtg ttcttccgcc agataacgct catgctcaga agagagatcg
    27721 actccccagt aaaccgggtt ttcaaacttc ctgccgcagt tttcgagaat ggtcactgcg
    27781 tcggtataat ccacctgcgc aaaatcggct tcaatgaagc gttccagacg tgaaacggca
    27841 tctttatcta cgcgttcagc gaagaatttc atgtcgtcag cgcgttcttc gagaaccgct
    27901 ttgaagacat atttcagcat ggcttcagcc agacccgcaa tatcgttcag gttagcaaac
    27961 gccacttccg gctccagcat ccagaattcc gccaggtgac ggctggtgtt ggagttttca
    28021 gcacggaaag tcgggccgaa ggtataaatt ttggacaatg cgcaagcgta ggtttcgccg
    28081 ttcaactggc cagatacggt caggaaagac tctttaccaa agaagtcttt gtcgaaatcc
    28141 actttgccct gatcgttacg cggcaggttt tccagatcca gcgtagaaac gcggaacatt
    28201 tcgcctgcac cttcggtatc agatgcggta atcagtggcg ttgaaaccca gaagaatccc
    28261 tgctcgttaa agaagcgatg cagcgcctgc gccagcgtat ggcgaacgcg cgcgacggca
    28321 ccaatcaggt ttgtgcgcgg acgcaggtga gcgacttcac gcagatactc aatgctgtgg
    28381 cgttttgccg ccatcgggta agtgtctgga tcttcaaccc aaccagcaac ttcaaccttg
    28441 ctggcctgaa tttcaaattg ttgcccctgg cccggcgacg ccacgacttt acccgtcaca
    28501 atgaccgagc agccggtggt cagacgcagg acgtcttcat tgtaattggg cagagaatta
    28561 ttgatgacag cctgtacagg atcaaagcag gaaccgtcat aaacggcgag gaaggagatg
    28621 ccagcttttg aatctcggcg ggtacgtacc catccgcgca cggtgacttc gctgtcaacg
    28681 gctacacggc cctggagtac gtcggctaca ggcacaacgc tcataatatt ctctctgtta
    28741 atagtcggaa aaaataaaca cttgtccacc cgtaaatggg gggataccta tgttacctgg
    28801 catctgcaat cagacaagca gaattcgcaa atgcagcgaa agatttcgga attaaaggta
    28861 aaaaaaggga gccgattagc tccctgatga tattaactgg cttttttaat atgcggaagg
    28921 tcgaacgctt tgcgcagcgc ccgaacaaac gctttatcat ggcagatagt tttgccaggg
    28981 ctgtcagaaa gtttcgccac cggtttaccg ttacactcta ccaacttaat gacaatattc
    29041 aggggtttta cctgggggat atcgcaggtc aggcgagtcc caataccaaa acttaattgc
    29101 acgcgggaag agaagtggcg gtatagctca accgctttgc gtaaatccag attgtcagag
    29161 aaaaccagcg ttttactctg tggatcaatt cccagctttt cataatgtgc aatggctttt
    29221 tcaccccatt caaccgggtc gccagagtca tgacgcaggc cctgataccg actagcgaac
    29281 tcgacaccga aatcacgcag gaaagcatcc atagtgatgc agtcggttaa tgcaatgcca
    29341 agttggtcgg gatactcttc cagccaggca gcaagtgcag ctcgctggct gttggctaga
    29401 tccgggctga tttgctgatg tgcctggaac cattcgtgtg cctgtgttcc catcggcgtg
    29461 agggaaagcc gacgcgccag atcgtagttg ctggtgccca caaaccagga ttcctgttgc
    29521 agacgcttaa cgatggtttc ttgtacttcg cgagaaaaac ggcgacgggt gccaaaatcc
    29581 atcagatgga agcgcgacat atcaagaccg gcggttaacg ccgagaagtc gactaatttg
    29641 ctttccagcg tgtcgagggc ttgcgcaacg tcggcctgcg gtgagcgata gcgatgtacc
    29701 atttcactga taaccgccag caaaggaact tcccagagga tgacttcacg ccacgggccg
    29761 cttaaacgaa tatccagctt gccattatcg ttggacacgg tgacttgttc cgggttaaag
    29821 cggaactcgc gtaaccagtt aagatagtcg gccttaaaga aaggcagggc agaaagccac
    29881 tgatattcat catcctgcag gcgcaggtgc tgcatcgcct gaacctgttc acgaatagca
    29941 tcggcataaa tacccagcag atcgtcacct cggcaacgaa actccgccgc gacatgcaca
    30001 tcgtaatagt gatgaaacac ggcttgctgc atatgcaact tataagcatc tgtatccagc
    30061 aacgagtgca gaacaggaga agcgaattgt gtcataggtg cgcagtagcg tcctcgtaca
    30121 ggagcgttta gtacaataaa catcttcagg aactgctgga gtataccttg tttcgcaatt
    30181 tattgaaccc cgatcacacc atatgccacc tttctggtcg atggcattac gcggtgtatg
    30241 ttataaaaat gtagcaataa aggcgtttgt acctgaaaag atgaagattc tgcatagcgc
    30301 gatttacgca acaggaatag actgaacacc agactctata aaagatgcta aaggttattt
    30361 atgactcaac agccacaagc caaataccgt cacgattatc gtgcgccgga ttaccagatt
    30421 actgatattg acttgacctt tgacctcgac gcgcaaaaga cggtcgttac cgcggtcagc
    30481 caggctgtcc gtcatggtgc atcagatgct ccccttcgtc tcaacggcga agacctcaaa
    30541 ctggtttctg ttcatattaa tgatgagccg tggaccgcct ggaaagaaga agagggcgca
    30601 ctggttatca gtaatttgcc ggagcgtttt acgcttaaga tcattaatga aataagcccg
    30661 gcggcgaata ccgcgctgga agggctttat cagtcaggcg atgcgctttg cacccagtgt
    30721 gaagccgaag gtttccgcca tattacgtat tatctcgacc gcccggacgt gctggcgcgt
    30781 tttaccacca aaattattgc cgataaaatc aaatatccct tcctgctttc caatggtaac
    30841 cgcgttgcgc aaggcgaact ggaaaacgga cgccattggg tacagtggca ggacccgttc
    30901 ccgaaaccgt gctacctgtt tgcgctggtg gcaggcgact ttgatgtact gcgcgatacc
    30961 tttaccacgc gttctggtcg cgaagtagca ctggagctgt acgtcgatcg cggcaacctt
    31021 gatcgcgcgc cgtgggcgat gacctcgctg aaaaactcca tgaaatggga tgaagaacgc
    31081 tttggcctgg agtatgacct cgacatctat atgatcgtcg cggtggattt cttcaatatg
    31141 ggcgcaatgg agaataaggg gctgaatatc tttaactcca aatatgtgct ggcccgcacc
    31201 gacaccgcca ccgacaaaga ttacctcgat attgaacgcg ttatcggcca tgaatatttc
    31261 cataactgga ccggtaaccg agtgacctgt cgcgactggt tccagctcag cctgaaagaa
    31321 ggtttaaccg tcttccgcga tcaggagttc agctctgacc ttggttcccg cgcagttaac
    31381 cgcatcaata atgtacgcac catgcgcgga ttgcagtttg cagaagacgc cagcccgatg
    31441 gcgcacccga tccgcccgga tatggtcatt gagatgaaca acttctacac cctgaccgtt
    31501 tacgagaagg gcgcggaagt gattcgcatg atccacaccc tgcttggcga agaaaacttc
    31561 cagaaaggga tgcagcttta tttcgagcgt catgatggta gtgcagcgac ctgtgacgac
    31621 tttgtgcagg cgatggaaga tgcgtcgaat gtcgatctct cccatttccg ccgttggtac
    31681 agccagtccg gtacaccgat tgtgaccgtc aaagacgact acaatccgga aaccgagcag
    31741 tacaccctga ccatcagcca gcgcacgcca gccacgccgg atcaggcaga aaaacagccg
    31801 ctgcatattc cgtttgccat cgaactgtat gataacgaag gcaaagtgat cccgttgcag
    31861 aaaggcggtc atccggtgaa ttccgtgctg aacgtcactc aggcggaaca gacctttgtc
    31921 tttgataatg tctacttcca gccggtgcct gcgctgctgt gcgaattctc tgcgccagtg
    31981 aaactggaat ataagtggag cgatcagcaa ctgaccttcc tgatgcgtca tgcgcgtaat
    32041 gatttctccc gctgggatgc ggcgcaaagt ttgctggcaa cctacatcaa gctgaacgtc
    32101 gcgcgtcatc agcaaggtca gccgctgtct ctgccggtgc atgtggctga tgctttccgc
    32161 gcggtactgc ttgatgagaa gattgatcca gcgctggcgg cagaaatcct gacgctgcct
    32221 tctgtcaatg aaatggctga attgttcgat atcatcgacc cgattgctat tgccgaagta
    32281 cgcgaagcac tcactcgtac tctggcgact gaactggcgg atgagctact ggctatttac
    32341 aacgcgaatt accagagcga gtaccgtgtt gagcatgaag atattgcaaa acgcactctg
    32401 cgtaatgcct gcctgcgttt cctcgctttt ggtgaaacgc atctggctga tgtgctggtg
    32461 agcaagcagt tccacgaagc aaacaatatg actgatgcgc tggcggcgct ttctgcggcg
    32521 gttgccgcac agctgccttg ccgtgacgcg ctgatgcagg agtacgacga caagtggcat
    32581 cagaacggtc tggtgatgga taaatggttt atcctgcaag ccaccagccc ggcggcgaat
    32641 gtgctggaga cggtgcgcgg cctgttgcag catcgctcat ttaccatgag caacccgaac
    32701 cgtattcgtt cgttgattgg cgcgtttgcg ggcagcaatc cggcagcgtt ccatgccgaa
    32761 gatggcagcg gttacctgtt cctggtggaa atgcttaccg acctcaacag ccgtaacccg
    32821 caggtggctt cacgtctgat tgaaccgctg attcgcctga aacgttacga tgccaaacgt
    32881 caggagaaaa tgcgcgcggc gctggaacag ttgaaagggc tggaaaatct ctctggcgat
    32941 ctgtacgaga agataactaa agcactggct tgataaataa ccgaatggcg gcaatagcgc
    33001 cgccattcgg ggaatttacc cctgttttct caggcgagtt tcagattcac cacgttgcat
    33061 cacccgttgc aacacctccg cttccagctc cgctaatcgc accgacccta atcgacgcgg
    33121 acgggggata tccactgtca aatccagacc aatttttccc tcttcaatta acagcacccg
    33181 gtcagccatc gctaccgctt cgctcacatc atgcgtcacc aacagtacgg taaagccgtg
    33241 ctcctgccaa agtgacacaa tcaaatcctg catctcgagt cgcgttaagg cgtccagcgc
    33301 cccgagcggt tcatcaagca acaataatcc cggtcgatga atcaacgctc ttgccagcgc
    33361 cactcgctgt ttctgcccgc cagaaagtgc ggcaggccat tcccctgcgc gattctccag
    33421 tcctaccgca gccaacgctc gacgtgcggc atcgcgccac tggcctttaa ggcctaaccc
    33481 aacgttatca atcaccgatt tccacggtag cagacgcgca tcctgaaaca tcattcgcgt
    33541 gtcttcctga atttcagcca gcggtgtggt gcccgctaac acatcgcctg cggttggcgt
    33601 ttccagacct gccagcaggc gcagcagggt acttttgcca ccaccgctgc ggcccaccac
    33661 cgccacaaac tgacctgccg gaatatgtaa atccagttgg ttcaggacga tattttccgc
    33721 gtaatgtttg cttactgcat tgagcaacaa tggcgtgccc tggttcagac gagcagtatt
    33781 cataccgtgg cctccttcaa atgataagcc gggttccagc gcaaccagag gcgctctaac
    33841 agctgcgcgc tgacgtcagc cagtttgccg agcagggcgt aaagaataat agcgactacc
    33901 accacgtccg tttgcaaaaa ctcccgcgca ttcatcgcca gataaccaat gcctgaattg
    33961 gcagaaatgg tttcggcaac aatcagcgtc agccacatca ggcccaacgc aaaacgcacg
    34021 ccgaccataa ttgagggcag ggcaccaggc aggatcacat ggataaacag cggtatgccg
    34081 gataatccat agctacgcgc catctccacc aacccgcgat cgatattacg gatgccatgc
    34141 caggtgttga tataaatggg gaatagcgta ccgagcgcca ccagaaagat ttttgcggat
    34201 tcatcaatgc caaaccacaa aatcaccagc gggatcagcg ccagatgcgg cacgttgcgc
    34261 aacatctgaa ttgaggtatc cagcagccgt tctccccagc gagatagccc gctaatcagt
    34321 cccaaaatca accccagcga tccgccaatt gaaaagccaa tcagcgcccg ccaggagctg
    34381 atcgccagat gctgccacag ttcgccgctg gcggagagcg tccagaacgc cgtcaccact
    34441 ccttccggtg aaggcaaaat acgcgtcgac agccagccaa ccgaggaggc cagttgccac
    34501 accgccacga tgcccaccgg taaaaaccag ggggcaacgc gcaataacca cttcttcact
    34561 ggcgttgcca ttatttcttc cttagctttg cgcgacttta cgggggataa aatcattcgc
    34621 caccgcttcg ccttgcggat tcagcggctg cggctgggga atttccggga tggcgacatc
    34681 cagaagcggg aacagcaact cgccaacccg atacgcttct tccagatgcg gatagcccga
    34741 aagcacaaaa ctgtcgatgc caagcgcggc atattcgttg attcgcgcag cgaccgtagg
    34801 accatcgccc accagcgccg tcccggcacc gccgcgcact aagccaacgc ccgcccataa
    34861 attggggctg atctccagat tgtcgcgctt gccgttatgt aacgccgcca ttcgctgttg
    34921 ccctacggaa tccgtccggg cgaatgcggc ctgtgctttg gcgatagttt catcatcaag
    34981 atgcgagatt aaccgctcgg cggcctgcca cgcttcgtcg ttagtttcac gaacaatcac
    35041 atgcagacga ataccgaaac gaattttgcg tccatgcgcg gcagctttcg cccgcacttg
    35101 ttcgattttc tctttaacca gttccggcgg ttcgccccag gtgaggtaga gatcaacctg
    35161 ttctgccgcc agctcctggg cgacatctga cgatccgcca aagtaaagtg gcggatacgg
    35221 ctgttgaatc gccgggaaga gcagttttgc tccgcgcaca tgaatatgtt taccgttgaa
    35281 atcgacggtt tctctctgca ataaacgccg ccagacctgg gtaaattccg ccgaggcttc
    35341 gtagcgctcg ctatgatcaa ggaacactcc gtcgcctgcc agctcttgtg gatcgctgcc
    35401 tgtgaccagg ttaaacaacg cacgtccatt tgagagacgg tcaagcgtgg cggcctggcg
    35461 ggcggcaacg gtaggtgagg ttacgctggg acgcagggcg acaagaaact tcagccgctg
    35521 cgtcaccggg atcatcgatg cggcaaccag ccacgcatct tcgcaggagc gccccgttgg
    35581 aattagcaca ccggtatagc caagacgatc cgccgcttgc gcaatttgtt gcagataacc
    35641 gtgatcaacc gggcgtgaac cttcttccgt tcccagataa tgcccgtcac cgtgggtcgg
    35701 taaaaaccag aacatattca gactcataat tgttttcctt ccagttgagt gggctgccag
    35761 atgcgctggc gaatatcgac ttttttcggc accagacgat tttcataaaa cagatctgcc
    35821 gtttgctgct gtaaggcggc aacctcggcg ttaaccggtt tgatggtggt aggagggcga
    35881 tgatctaagt aagaggcaat caccggtgcc ggtaagccca tcgtttttgc cagtaaagcg
    35941 atgctttgct cgcgctggct gcgggttaac gcatcggcct cactaaaggt tgccagtacg
    36001 ccctgaataa aagcgccgtt tttttctgca tagggacgag ctgccagata aaacgatcca
    36061 gtttgattga gatcggtgcc gtctttcagc acccgcacgc cgccctgtaa taatgcagca
    36121 gagtagtagg gatcccagat agcccaggcg tcaacgttac cttgctggaa cgcggcgcgg
    36181 gcatcagcgg gcgtcaggta agtgggttgg atatcggtaa acttaagtcc ggcctgacgc
    36241 agtgcacgca gtaaaaggtt gtgtgaactg gaacctttct gaaaggcaac tttgtgacct
    36301 ttaagatcgg ctacggtttt gatcgggctg ttttctgcca ccagaatcac ttcggctttg
    36361 ggcttcggtg gctcgacgcc cacgtacacc aaatcagccc cggcagcctg ggcaaagatt
    36421 ggcggaatat ccccggtact gccgagatca atactgccaa cgtttaacgc ttccaacatt
    36481 tgcggacccg cggggaactc cacccaggag atttttgatt ccggatagcg tttttccagt
    36541 aactggtggc tttttgccag caccatacca atactgcctt tctgatagcc tatacgtaac
    36601 gcttcaggcg aggattctgc agcaaccgca aaagtagaga cgctaagcaa tcccgccagc
    36661 gccagtttaa tgatgttacg catgggcatt acctcgcaga gacagaaggt caggaacctg
    36721 aacatcgcgg cggtgcaatg cctgccagaa agtttctagc gcggtatcaa gacgggtttg
    36781 cagatttggc gtgaactggg gtctgtgatg gtaatcaatt acttgtgagt catcggcaaa
    36841 cacgccgtgc aggatctcct gagctttcag tgcgcttaaa actggtttaa gggcataatc
    36901 gaccgccagc agatgggcca cggtaccgcc cgtcgccagc ggtagcacca ctttgccttg
    36961 caaagcgcgt tctggcagca ggtcgagcag ggttttcaac gcaccggaat aggcggcttt
    37021 atacacaggc gtggcgacaa tcagcccatc ggcctgttgc agctgttcgg tgaaggtctt
    37081 gagtgccgga ctatcgaaac gagcataaag tagatcttcc ggggcgaagt tttgcagatt
    37141 ccagtgataa acctctacat ccaggccatt tagtttttcc cgcgcatatt ccagcaagga
    37201 gctggagcga gaaggaaagc gaggactacc cgccagggtg atgacacgca tactctctcc
    37261 ttataaccaa ttgttctttt tttgttaaca ttgataacaa ttcggtcagt ctgtcggaga
    37321 gacaagaaaa ttccaaatat aaattttgtg tatctttttc t
//
LOCUS       DAPOAV010000042        35993 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.042, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000042 DAPOAV010000000
VERSION     DAPOAV010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 35993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35993
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.042"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..671)
                     /locus_tag="RN951_002358"
     CDS             complement(<1..671)
                     /locus_tag="RN951_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS element protein"
                     /protein_id="HDX2527348.1"
                     /translation="MSGKPAARQGDMTQYGGSIVQGSAGVRIGAPTGVACSVCPGGVT
                     SGHPVNPLLGAKVLPGETDIAQPGPLPFILSRTYSSYRTKTPAPVGSLGPGWKMPADI
                     RLQLRDNTLILSDNGGRSLYFEHLFPGEDGYSRSESLWLVRGGVAKLDEGHRLAALWQ
                     ALPEELRLSPHRYLATNSPQGPWWVLGWCERVPEADEVLPAPLPPYRVLTGLVDRFGR
                     TQTFHR"
     gene            complement(874..1275)
                     /gene="nikR"
                     /locus_tag="RN951_002359"
     CDS             complement(874..1275)
                     /gene="nikR"
                     /locus_tag="RN951_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-responsive transcriptional regulator
                     NikR"
                     /protein_id="HDX2527349.1"
                     /translation="MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEA
                     TQQHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLK
                     GDMGDVQHFADDVIAQRGVRHGHLQCLPKED"
     gene            complement(1281..2087)
                     /gene="nikE"
                     /locus_tag="RN951_002360"
     CDS             complement(1281..2087)
                     /gene="nikE"
                     /locus_tag="RN951_002360"
                     /EC_number="7.2.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel import ATP-binding protein NikE"
                     /protein_id="HDX2527350.1"
                     /translation="MTLLNVCGLSHHYAHGGFSGKHQHQAVLNNVSLTLKSGETVALL
                     GRSGCGKSTLARLLVGLESPSQGNISWRGEPLAKLNRAQRKAFRRDIQMVFQDSISAV
                     NPRKTVREILREPMRHLLSLKKSEQLARASEMLKAVDLDDSVLDKRPPQLSGGQLQRV
                     CLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERF
                     CQRVMVMDNGQIVETQVVGDKLTFSSDAGRVLQNAVLPAFPVRRRTTEKV"
     gene            complement(2084..2848)
                     /gene="nikD"
                     /locus_tag="RN951_002361"
     CDS             complement(2084..2848)
                     /gene="nikD"
                     /locus_tag="RN951_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel import ATP-binding protein NikD"
                     /protein_id="HDX2527351.1"
                     /translation="MPQQIELRNIALQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSL
                     TCAATLGILPAGVRQTAGEILADGKPVSPCALRGIKIATIMQNPRSAFNPLHTMHTHA
                     RETCLALGKPADDATLTAAIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESP
                     FIIADEPTTDLDVVAQARILDLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSQGK
                     IVEQGDVETLFNAPKHTVTRSLVSAHLALYGMELAS"
     gene            complement(2848..3681)
                     /gene="nikC"
                     /locus_tag="RN951_002362"
     CDS             complement(2848..3681)
                     /gene="nikC"
                     /locus_tag="RN951_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter permease subunit NikC"
                     /protein_id="HDX2527352.1"
                     /translation="MNFFLSSRWSVRLALIIIALLALIALTSQWWLPYDPQAIDLPSR
                     LLSPDAQHWLGTDHLGRDIFSRLMAATRVSLGSVMACLLLVLTLGLVIGGSAGLIGGR
                     VDQATMRVADMFMTFPTSILSFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISL
                     RQREFVLASRLSGAGHVRVFVDHLAGAVIPSLLVLATLDIGHMMLHVAGMSFLGLGVT
                     APTAEWGVMINDARQYIWTQPLQMFWPGLALFISVMAFNLVGDALRDHLDPHLVTEHA
                     H"
     gene            complement(3678..4622)
                     /gene="nikB"
                     /locus_tag="RN951_002363"
     CDS             complement(3678..4622)
                     /gene="nikB"
                     /locus_tag="RN951_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter permease subunit NikB"
                     /protein_id="HDX2527353.1"
                     /translation="MLRYVLRRFLLLIPMVLAASVIIFLMLRLGTGDPALDYLRLSNL
                     PPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDFGISFASQRPVLDDMLNFLPATL
                     ELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSV
                     YLQWLPAMGYGGWQHIILPAVSIAFMSLAINARLLRASMLDVAGQRHVTWARLRGLND
                     KQTERRHILRNASLPMITAVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPV
                     IQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRHEGAHA"
     gene            complement(4622..6196)
                     /gene="nikA"
                     /locus_tag="RN951_002364"
     CDS             complement(4622..6196)
                     /gene="nikA"
                     /locus_tag="RN951_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HDX2527354.1"
                     /translation="MLSTLRRTLFALLACASFIVHAAAPDEITTAWPVNVGPLNPHLY
                     TPNQMFAQSMVYEPLVKYQADGSVIPWLAKSWTHSEDGKTWTFTLRDDVKFSNGEPFD
                     AEAAAENFRAVLDNRQRHAWLELANQIVDVKALSKTELQITLKSAYYPFLQELALPRP
                     FRFIAPSQFKNHETMNGIKAPIGTGPWILQESKLNQYDVFVRNENYWGEKPAIKKITF
                     NVIPDPTTRAVAFETGDIDLLYGNEGLLPLDTFARFSQNPAYHTQLSQPIETVMLALN
                     TAKAPTNELAVREALNYAVNKKSLIDNALYGTQQVADTLFAPSVPYANLGLKPRQYDP
                     QKAKELLEKAGWTLPAGKDIREKNGQPLRIELSFIGTDALSKSMAEIIQADMRQIGAD
                     VSLIGEEESSIYARQRDGRFGMIFHRTWGAPYDPHAFLSSMRVPSHADFQAQQGLADK
                     PLIDKEIGEVLATHDETQRQALYRDILTRLHDEAVYLPISYISMMVVSKPELGNIPYA
                     PIATEIPFEQIKPVKP"
     gene            complement(6307..6894)
                     /gene="acpT"
                     /locus_tag="RN951_002365"
     CDS             complement(6307..6894)
                     /gene="acpT"
                     /locus_tag="RN951_002365"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase AcpT"
                     /protein_id="HDX2527355.1"
                     /translation="MYRIVLGKVSTLSAAPLPPGLREQAPQGPRRERWLAGRALLSHT
                     LSPLPEIIYGEQGKPAFAPETPLWFNLSHSGDDIALLLSDEGEVGCDIEVIRPRANWR
                     WLANAVFSLGEHAEMDAVHPDQQLEMFWRIWTRKEAIVKQRGGSAWQIVSVDSTYHSS
                     LSVSHCQLENLSLAICTPTPFTLTADSVQWIDSVN"
     gene            complement(6949..7998)
                     /locus_tag="RN951_002366"
     CDS             complement(6949..7998)
                     /locus_tag="RN951_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312350.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDX2527356.1"
                     /translation="METPQPDKTGMHILLKLASLVVILAGIHAAADIIVQLLLALFFA
                     IVLNPLVTWFIRRGVQRPVAITIVVVVMLIALTALVGVLAASFNEFISMLPKFNKELT
                     RKLFKLQEMLPFLNLHMSPERMLQRMDSEKVVTFTTALMTGLSGAMASVLLLVMTVVF
                     MLFEVRHVPYKMRFALNNPQIHIAGLHRALKGVSHYLALKTLLSLWTGVIVWLGLELM
                     GVQFALMWAVLAFLLNYVPNIGAVISAVPPMIQVLLFNGIYECILVGALFLVVHMVIG
                     NILEPRMMGHRLGMSTMVVFLSLLIWGWLLGPVGMLLSVPLTSVCKIWMETTKGGSKL
                     AILLGPGRPKSRLPG"
     gene            8130..9347
                     /locus_tag="RN951_002367"
     CDS             8130..9347
                     /locus_tag="RN951_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417930.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2527357.1"
                     /translation="MPEPVAEPALNGLRLNLRIVSIVMFNFASNLTIGLPLAVLPGYV
                     HDVMGFSAFWAGLVISLQYFATLLSRPHAGRYADLLGPKKIVVFGLCGCFLSGLGYLT
                     AGLTASLPVISLLLLCLGRVILGIGQSFAGTGSTLWGVGVVGSLHIGRVISWNGIVTY
                     GAMAMGAPLGVVFYHWGGLQALALIIMGVALVAILLAIPRPTVKASKGKPLPFRAVLG
                     SVWLYGMALALASAGFGVIATFITLFYDAKGWDGAAFALTLFSCAFVGTRLLFPNGIN
                     RIGGLNVAMICFSVEIIGLLLVGVATMPWMAKIGVLLAGAGFSLVFPALGVVAVKAVP
                     QQNQGAALATYTVFMDLSLGVTGPLAGLVMSWAGVPVIYLAAAGLVAIALLLTWRLKK
                     RPPEHVPEAASSS"
     gene            complement(9351..9908)
                     /gene="dcrB"
                     /locus_tag="RN951_002368"
     CDS             complement(9351..9908)
                     /gene="dcrB"
                     /locus_tag="RN951_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417929.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage sensitivity protein DcrB"
                     /protein_id="HDX2527358.1"
                     /translation="MRNLVKYVGIGLLVMGLAACDDKDTNATAQGSVAESNATGNPVN
                     LLDGKLSFSLPADMTDQSGKLGTQANNMHVWSDATGQKAVIVIMGDDPKEDLAVLAKR
                     LEDQQRSRDPQLQVVTNKAIELKGHKMQQLDSIISAKGQTAYSSVILGNVGNQLLTMQ
                     ITLPADDQQKAQTTAENIINTLVIQ"
     gene            complement(9981..10646)
                     /locus_tag="RN951_002369"
     CDS             complement(9981..10646)
                     /locus_tag="RN951_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine/7-aminomethyl-7-
                     deazaguanine transporter"
                     /protein_id="HDX2527359.1"
                     /translation="MNVFSQTQRYKALFWLSLFHLLVITSSNYLVQLPVSILGFHTTW
                     GAFSFPFIFLATDLTVRIFGAPLARRIIFAVMIPALLISYVISSLFYMGSWQGFGALA
                     HFNLFVARIATASFMAYALGQILDVHVFNRLRQSRRWWLAPTASTLFGNVSDTLAFFF
                     IAFWRSPDAFMAEHWMEIALVDYCFKVLISIVFFLPMYGVLLNMLLKRLADKSEINAL
                     QAS"
     gene            10867..11112
                     /gene="tusA"
                     /locus_tag="RN951_002370"
     CDS             10867..11112
                     /gene="tusA"
                     /locus_tag="RN951_002370"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA"
                     /protein_id="HDX2527360.1"
                     /translation="MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIAD
                     DPATTRDIPGFCTFMEHELVAKETDGLPYRYLIRKGG"
     gene            complement(11214..13412)
                     /gene="zntA"
                     /locus_tag="RN951_002371"
     CDS             complement(11214..13412)
                     /gene="zntA"
                     /locus_tag="RN951_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase
                     ZntA"
                     /protein_id="HDX2527361.1"
                     /translation="MSTPDNHGKKAPQFAAFKPLTTVQNANDCCCDGACSSSPTLSEN
                     VSGTRYSWKVSGMDCAACARKVENAVRQLAGVNQVQVLFATEKLVVDADNDIRAQVES
                     AVQKAGYSLRDEQAADEPQASRLKENLPLITLIVMMAISWGLEQFNHPFGQLAFIATT
                     LVGLYPIARQALRLIKSGSYFAIETLMSVAAIGALFIGATAEAAMVLLLFLIGERLEG
                     WAASRARQGVSALMALKPETATRLRKGEREEVAINSLRPGDVIEVAAGGRLPADGKLL
                     SPFASFDESALTGESIPVERATGDKVPAGATSVDRLVTLEVLSEPGASAIDRILKLIE
                     EAEERRAPIERFIDRFSRIYTPAIMAVALLVTLVPPLLFAASWQEWIYKGLTLLLIGC
                     PCALVISTPAAITSGLAAAARRGALIKGGAALEQLGRVTQVAFDKTGTLTVGKPRVTA
                     IHPATGISESELLTLAAAVEQGATHPLAQAIVREAQVAELAIPTAESQRALVGSGIEA
                     QVNGERVLICAAGKHPADAFTGLINELESAGQTVVLVVRNDDVLGIIALQDTLRADAA
                     TAISELNALGVKGVILTGDNPRAAAAIAGELGLEFKAGLLPEDKVKAVTELNQHAPLA
                     MVGDGINDAPAMKAAAIGIAMGSGTDVALETADAALTHNHLRGLVQMIELARATHANI
                     RQNITIALGLKGIFLVTTLLGMTGLWLAVLADTGATVLVTANALRLLRRR"
     gene            complement(13486..14112)
                     /locus_tag="RN951_002372"
     CDS             complement(13486..14112)
                     /locus_tag="RN951_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysoplasmalogenase"
                     /protein_id="HDX2527362.1"
                     /translation="MLWSFIAVCLSAWLSVDASYRGPTWQRWVFKPLTLLLLLLLAWQ
                     APMFDAISYLVLAGLCASLLGDALTLLPRQRLMYAIGAFFLSHLLYTIYFASQMTLSF
                     FWPLPLVLLVLGALLLAIIWTRLEEYRWPICTFIGMTLVMVWLAGELWFFRPTAPALS
                     AFVGASLLFISNFVWLGSHYRRRFRADNAIAAACYFAGHFLIVRSLYL"
     gene            14253..14612
                     /locus_tag="RN951_002373"
     CDS             14253..14612
                     /locus_tag="RN951_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2500 domain-containing protein"
                     /protein_id="HDX2527363.1"
                     /translation="MSKPPLFFIVIIGLIVVAASFRFMQQRREKADNDMAPLQQKLVV
                     VSNKREKPINDRRSRQQEVTPAGTSMRYEASFKPQSGGMEQTFRLDAQQYHALTVGDK
                     GTLSYKGTRFVSFVGEQ"
     gene            complement(14615..14884)
                     /locus_tag="RN951_002374"
     CDS             complement(14615..14884)
                     /locus_tag="RN951_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1145 family protein"
                     /protein_id="HDX2527364.1"
                     /translation="MLINIGRLLMLCVWGFLILNLVHPFPRPLNIFVNVALIFTVLMH
                     GMQLALLKSTLPKDGPQMTTAEKVRIFLFGVFELLVWQKKFKVKK"
     gene            complement(14874..15470)
                     /gene="rsmD"
                     /locus_tag="RN951_002375"
     CDS             complement(14874..15470)
                     /gene="rsmD"
                     /locus_tag="RN951_002375"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase"
                     /protein_id="HDX2527365.1"
                     /translation="MKKPNHSGSGQIRIIGGQWRGRKLPVPDSPGLRPTTDRVRETLF
                     NWLAPVIVDAQCLDCFAGSGALGLEALSRYAAGATLIEMDRAVSQQLIKNLATLKAGN
                     ARVVNSNAMSFLAQKGTPHNIVFVDPPFRRGLLEETINLLEDNGWLADEALIYVESEV
                     ENGLPTVPANWSLHREKVAGQVAYRLYQREAQGESDAD"
     gene            15620..17113
                     /gene="ftsY"
                     /locus_tag="RN951_002376"
     CDS             15620..17113
                     /gene="ftsY"
                     /locus_tag="RN951_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HDX2527366.1"
                     /translation="MAKEKKRGFFSWLGFGQKEQTPEKETEVQNEQPVVEEIVQAQEP
                     VKASEQAVEEQPQAHTEAEAETFAADVVEVTEQVAESEKAQPEAEVVAQPEPVVEETP
                     EPVAIEREELPLPEDVNAEAVSPEEWQAEAETVEIVEAAEEEAAKEEITDEELETALA
                     AEAAEEAVMVVPPAEEEQPVEEIAQEQEKPTKEGFFARLKRSLLKTKENLGSGFISLF
                     RGKKIDDDLFEELEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMG
                     EILAKVDEPLNVEGKAPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFRA
                     AAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKSH
                     LMEELKKIVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDG
                     TAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKADDFIEALFARED"
     gene            17116..17784
                     /gene="ftsE"
                     /locus_tag="RN951_002377"
     CDS             17116..17784
                     /gene="ftsE"
                     /locus_tag="RN951_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HDX2527367.1"
                     /translation="MIRFEHVSKAYLGGRQALQGVTFHMQPGEMAFLTGHSGAGKSTL
                     LKLICGIERPSAGKIWFSGHDITRLKNREVPFLRRQIGMIFQDHHLLMDRTVYDNVAI
                     PLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLL
                     ADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDINLISRRSYRMLTLSDGHLHGG
                     VGHE"
     gene            17777..18835
                     /gene="ftsX"
                     /locus_tag="RN951_002378"
     CDS             17777..18835
                     /gene="ftsX"
                     /locus_tag="RN951_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsX"
                     /protein_id="HDX2527368.1"
                     /translation="MNKRDAINHIRQFGGRLDRFRKSVGGSGDGGRNAPKRAKSSPKP
                     VNRKTNVFNEQVRYAFHGALQDLKSKPFATFLTVMVIAISLTLPSVCYMVYKNVNQAA
                     TQYYPSPQITVYLQKTLDDDAAAGVVAQLQAEQGVEKVNYLSREDALGEFRNWSGFGG
                     ALDMLEENPLPAVAVVIPKLDFQGTESLNTLRDRITQINGIDEVRMDDSWFARLAALT
                     GLVGRVSAMIGVLMVAAVFLVIGNSVRLSIFARRDSINVQKLIGATDGFILRPFLYGG
                     ALLGFSGALLSLILSEILVLRLSSAVAEVAQVFGTKFDINGLSFDECLLLLLVCSMIG
                     WVAAWLATVQHLRHFTPE"
     gene            19080..19934
                     /gene="rpoH"
                     /locus_tag="RN951_002379"
     CDS             19080..19934
                     /gene="rpoH"
                     /locus_tag="RN951_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoH"
                     /protein_id="HDX2527369.1"
                     /translation="MTDKMQSLALAPVGNLDSYIRAANAWPMLSADEERALAEKLHYH
                     GDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLV
                     SFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRLGWFNQDEVEMVARE
                     LGVTSKDVREMESRMAAQDMTFDLSSDDDSDSQPMAPVLYLQDKSSNFADGIEDDNWE
                     EQAANRLTDAMQGLDERSQDIIRARWLDEDNKSTLQELADRYGVSAERVRQLEKNAMK
                     KLRAAIEA"
     gene            20205..21308
                     /gene="livJ"
                     /locus_tag="RN951_002380"
     CDS             20205..21308
                     /gene="livJ"
                     /locus_tag="RN951_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     substrate-binding protein LivJ"
                     /protein_id="HDX2527370.1"
                     /translation="MNIKGKALLAGCIALAFSNMALAEDIKVAVVGAMSGPVAQYGDQ
                     EFTGAEQAVADINAKGGIKGNKLQIVKYDDACDPKQAVAVANKVVNDGIKYVIGHLCS
                     SSTQPASDIYEDEGILMITPAATAPELTARGYQLILRTTGLDSDQGPTAAKYILEKVK
                     PQRIAIVHDKQQYGEGLARAVQDGLKKGNANVVFFDGITAGEKDFSTLVARLKKENID
                     FVYYGGYHPEMGQILRQARAAGLKTQFMGPEGVANVSLSNIAGESAEGLLVTKPKNYD
                     QVPANKPIVDAIKAKKQDPSGAFVWTTYAALQSLQAGLNQSDDPAEIAKYLKANSVDT
                     VMGPLTWDEKGDLKGFEFGVFDWHANGTATDAK"
     gene            complement(21507..21890)
                     /gene="panM"
                     /locus_tag="RN951_002381"
     CDS             complement(21507..21890)
                     /gene="panM"
                     /locus_tag="RN951_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase autocleavage activator
                     PanM"
                     /protein_id="HDX2527371.1"
                     /translation="MKLTIIRLENFSDQDRIDLQKIWPEYSPSSLQVDDNHRIYAARF
                     NERLLAAVRVTLSGTEGALDSLRVREVTRRRGVGQYLLEEVLRNNPAVSCWWMADAGV
                     EDRGVMTAFMQALGFTAQQGGWEKR"
     gene            22314..23423
                     /gene="livK"
                     /locus_tag="RN951_002382"
     CDS             22314..23423
                     /gene="livK"
                     /locus_tag="RN951_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter substrate-binding protein LivK"
                     /protein_id="HDX2527372.1"
                     /translation="MKRNAKTIIAGMIALAISHTAMADDIKVAVVGAMSGPIAQWGDM
                     EFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIVNDGIKYVIGHLCS
                     SSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLDSSQGPTAAKYILETVK
                     PQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKENID
                     FVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAAEGMLVTMPKRYD
                     QDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPLALVKDLKANGA
                     NTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTAAK"
     gene            23471..24397
                     /gene="livH"
                     /locus_tag="RN951_002383"
     CDS             23471..24397
                     /gene="livH"
                     /locus_tag="RN951_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter permease LivH"
                     /protein_id="HDX2527373.1"
                     /translation="MSEQFLYFLQQMFNGVTLGSTYALIAIGYTMVYGIIGMINFAHG
                     EVYMIGSYVSFMIIAALMMMGIDTGWLLVAAGFVGAIVIASAYGWSIERVAYRPVRNS
                     KRLIALISAIGMSIFLQNYVSLTEGSRDVALPSLFNGQWVVGHSENFSASITTMQAVI
                     WIVTFLAMLALTVFIRYSRMGRACRACAEDLKMASLLGINTDRVIALTFVIGAAMAAV
                     AGVLLGQFYGVINPYIGFMAGMKAFTAAVLGGIGSIPGAMIGGLILGIAEALSSAYLS
                     TEYKDVVSFALLILVLLVMPTGILGRPEVEKV"
     gene            24394..25671
                     /gene="livM"
                     /locus_tag="RN951_002384"
     CDS             24394..25671
                     /gene="livM"
                     /locus_tag="RN951_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     permease LivM"
                     /protein_id="HDX2527374.1"
                     /translation="MKPMHIAMALLSAAMFFVLAGVFMGVQLELDGTKLVVDTASDVR
                     WQWVFIGTAVVFFFQLLRPAFQKGLKSVSGPKFILPAIDGSTVKQKLFLVALLVLAVA
                     WPFMVSRGTVDIATLTMIYIILGLGLNVVVGLSGLLVLGYGGFYAIGAYTFALLNHYY
                     GLGFWTCLPIAGLMAAAAGFLLGFPVLRLRGDYLAIVTLGFGEIVRILLLNNTEITGG
                     PNGISQIPKPTLFGLEFSRTAREGGWDTFSNFFGLKYDPSDRVIFLYLVALLLVVLSL
                     FVINRLLRMPLGRAWEALREDEIACRSLGLSPRRIKLTAFTISAAFAGFAGTLFAARQ
                     GFVSPESFTFAESAFVLAIVVLGGMGSQFAVILAAILLVVSRELMRDFNEYSMLMLGG
                     LMVLMMIWRPQGLLPMTRPQLKLKNGAAKGEQA"
     gene            25668..26435
                     /gene="livG"
                     /locus_tag="RN951_002385"
     CDS             25668..26435
                     /gene="livG"
                     /locus_tag="RN951_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivG"
                     /protein_id="HDX2527375.1"
                     /translation="MSQPLLSVNGLMMRFGGLLAVNNVNLELYPQEIVSLIGPNGAGK
                     TTVFNCLTGFYKPTGGTILLRDQHLEGLPGQQIARMGVVRTFQHVRLFREMTVIENLL
                     VAQHQQLKTGLFSGLLKTPSFRRAQSEALDRAATWLERIGLLEHANRQASNLAYGDQR
                     RLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNHHNTTILLIEHDMKLVM
                     GISDRIYVVNQGTPLANGTPEQIRNNPDVIRAYLGEA"
     gene            26437..27150
                     /gene="livF"
                     /locus_tag="RN951_002386"
     CDS             26437..27150
                     /gene="livF"
                     /locus_tag="RN951_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417911.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivF"
                     /protein_id="HDX2527376.1"
                     /translation="MEKVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGK
                     TTLLGTLCGDPRATSGRIVFDDKDITDWQTAKIMREAVAIVPEGRRVFSRMTVEENLA
                     MGGFFAERDQFQERIKWVYELFPRLHERRIQRAGTMSGGEQQMLAIGRALMSNPRLLL
                     LDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVVLS
                     DTGDALLANEAVRSAYLGG"
     gene            27549..28865
                     /gene="ugpB"
                     /locus_tag="RN951_002387"
     CDS             27549..28865
                     /gene="ugpB"
                     /locus_tag="RN951_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     substrate-binding protein UgpB"
                     /protein_id="HDX2527377.1"
                     /translation="MKPLHYTASALALGLALMGNAQAVTTIPFWHSMEGELGKEVDSL
                     AQRFNAENPDYKIVPTYKGNYEQNLSAGIAAFRTGNAPAILQVYEVGTATMMASKAIK
                     PVYDVFKEAGIQFDESQFVPTVSGYYSDSKTGHLLSQPFNSSTPVLYYNKDAFKKAGL
                     DPEQPPKTWQDLADYAAKLKASGMKCGYASGWQGWIQLENFSAWNGLPFASKNNGFDG
                     TDAVLEFNKPEQVKHIAMLEEMNKKGDFSYVGRKDESTEKFYNGDCAMTTASSGSLAN
                     IREYAKFNYGVGMMPYDADAKDAPQNAIIGGASLWVMQGKDKETYTGVAKFLDFLAKP
                     ENAAEWHQKTGYLPITKAAYDLTREQGFYEKNPGADTATRQMLNKPPLPFTKGLRLGN
                     MPQIRVIVDEELESVWTGKKTPQQALDTAVERGNQLLRRFEKSTKS"
     gene            28963..29850
                     /gene="ugpA"
                     /locus_tag="RN951_002388"
     CDS             28963..29850
                     /gene="ugpA"
                     /locus_tag="RN951_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpA"
                     /protein_id="HDX2527378.1"
                     /translation="MSSSRPVFRSRWLPYLLVAPQLIITVIFFIWPAGEALWYSLQSV
                     DPFGFSSQFVGLDNFVTLFHDSYYLDSFWTTIKFSTFVTVSGLLVSLFFAALVEYIVR
                     GSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGQAMFL
                     VVFASVWKQISYNFLFFYAALQSIPRSLIEAAAIDGAGPIRRFFKIALPLIAPVSFFL
                     LVVNLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYREGFTGLDLASSAAQSVVLMFL
                     VIVLTVVQFRYVESKVRYQ"
     gene            29847..30692
                     /gene="ugpE"
                     /locus_tag="RN951_002389"
     CDS             29847..30692
                     /gene="ugpE"
                     /locus_tag="RN951_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpE"
                     /protein_id="HDX2527379.1"
                     /translation="MIENRPWLTIFSHTMLILGIAVILFPLYVAFVAATLDKQAVYAA
                     PMTLIPGTHLLENIHNIWVNGVGTNSAPFWRMLLNSFVMAFSITLGKITVSMLSAFAI
                     VWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLQMLDSYAGLTLPLMASATATF
                     LFRQFFMTLPDELVEAARIDGASPMRFFCDIVFPLSKTNLAALFVITFIYGWNQYLWP
                     LLIITDVDLGTTVAGIKGMIATGEGTTEWNSVMAAMLLTLIPPVVIVLVMQRAFVRGL
                     VDSEK"
     gene            30694..31764
                     /gene="ugpC"
                     /locus_tag="RN951_002390"
     CDS             30694..31764
                     /gene="ugpC"
                     /locus_tag="RN951_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312323.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol 3-phosphate ABC transporter ATP
                     binding protein UgpC"
                     /protein_id="HDX2527380.1"
                     /translation="MAGLKLQAVTKSWDGKTQVIKPLTLDVADGEFIVMVGPSGCGKS
                     TLLRMVAGLERVTEGDIWINDQRVTEMEPKDRGIAMVFQNYALYPHMSVEENMAWGLK
                     IRGMGKQQIAERVKEAARILELDGLLKRRPRELSGGQRQRVAMGRAIVRDPAVFLFDE
                     PLSNLDAKLRVQMRLELQQLHRRLKTTSLYVTHDQVEAMTLAQRVMVMNGGVAEQIGT
                     PVEVYEKPASLFVASFIGSPAMNLLTGRVNNEGTHFELDGGIVLPLNGGYRQYAGRKM
                     TLGIRPEHIALSSQAEGGVPLVMDTLEILGADNLAHGRWSEQKLVVRLAHQERPTAGS
                     TLWLHLPENQLHLFDGETGQRV"
     gene            31761..32504
                     /gene="ugpQ"
                     /locus_tag="RN951_002391"
     CDS             31761..32504
                     /gene="ugpQ"
                     /locus_tag="RN951_002391"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDX2527381.1"
                     /translation="MNNWPYPRIVAHRGGGKLAPENTLAAIDVGAKYGHKMIEFDAKL
                     SKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVDAGSWYSKAFKGEPLPLLSQVAE
                     RCREHGMMANIEIKPTTGTGPLTGKMVALAARQLWAGMTPPLLSSFEIDALEAAQLAA
                     PELPRGLLLDEWRDDWRELTARLGCVSIHLNHKLLDKVRVMQLKDAGLRILVYTVNKP
                     QRAAELLRWGVDCICTDAIDVIGPNFTAQ"
     gene            complement(32491..32931)
                     /locus_tag="RN951_002392"
     CDS             complement(32491..32931)
                     /locus_tag="RN951_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2756 family protein"
                     /protein_id="HDX2527382.1"
                     /translation="MKRLLILTALLPFVGFAQPINTLNNPNQPGYQIPSQQRMQTQMQ
                     TQQIQQKGMLNQQLKTQTQLQQQHLENQINNNSQRVLQSQPGERNPARQQMLPNTNGG
                     MLNSNRNPDSSLNQQHMLPERRNGDMLNQPSTPQPDIPLKTIGP"
     gene            33051..34793
                     /gene="ggt"
                     /locus_tag="RN951_002393"
     CDS             33051..34793
                     /gene="ggt"
                     /locus_tag="RN951_002393"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HDX2527383.1"
                     /translation="MIKPTFLRRVAIAALLSGSCFSAAAAPPAPPVSYGVEEDVFHPV
                     RAKQGMVASVDATATQVGVDILKEGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLIR
                     SKNGNTTAIDFREMAPAKATRDMFLDDQGNPDSKKSLTSHLASGTPGTVAGFSLALDK
                     YGTMPLNKVVQPAFKLARDGFIVNDALADDLKTYGSEVLPNHENSKAIFWKEGEPLKK
                     GDTLVQANLAKSLEMIAENGPDEFYKGTIAEQIAQEMQKNGGLITKEDLAAYKAVERT
                     PISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAY
                     ADRSEYLGDPDFVKVPWQALTNKAYAKSIADQIDINKAKPSSEIRPGKLAPYESNQTT
                     HYSVVDKDGNAVAVTYTLNTTFGTGIVAGESGILLNNQMDDFSAKPGVPNVYGLVGGD
                     ANAVGPNKRPLSSMSPTIVVKDGKTWLVTGSPGGSRIITTVLQMVVNSIDYGLNVAEA
                     TNAPRFHHQWLPDELRVEKGFSPDTLKLLEAKGQKVALKEAMGSTQSIMVGPDGELYG
                     ASDPRSVDDLTAGY"
     gene            complement(34831..35115)
                     /locus_tag="RN951_002394"
     CDS             complement(34831..35115)
                     /locus_tag="RN951_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhB family protein"
                     /protein_id="HDX2527384.1"
                     /translation="MITYHDAFAKANHYLDDADLPVVITLHGRFSQGWYFCFEAREFL
                     ETGDEAARLAGNAPFIIDKDSGEIHSLGTAKPLEEYLQDYEIKKATFGLP"
     gene            complement(35315..35470)
                     /locus_tag="RN951_002395"
     CDS             complement(35315..35470)
                     /locus_tag="RN951_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527385.1"
                     /translation="MEKLTTELHSLSEMDRRHVVSILAEIANGYDDFNDMLIYLEFYP
                     NHKILIS"
     gene            complement(35565..>35993)
                     /locus_tag="RN951_002396"
     CDS             complement(35565..>35993)
                     /locus_tag="RN951_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001759491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527386.1"
                     /translation="APLKESFIESIIQIEFNSNSTNCLEKLCNEVSILFKNQPDYLTF
                     LRAMDGFEVNGLRLFSLSIPEPSVKNLFAVNEFYRNNDDFINPDLQERLVIGDYSISI
                     FTYDIKSNFFEIRDNIGTENIFSSFSDFSSFLNEIMDSCS"
BASE COUNT         8383 a         9326 c        10027 g         8257 t
ORIGIN      
        1 cggtggaacg tctgtgtgcg cccgaagcgg tccaccagcc cggtcagtac ccggtacggc
       61 ggcagcggcg caggcagcac ctcatccgct tccggcaccc gctcacacca gccgagtacc
      121 caccacggcc cctgcggact gtttgtcgcc agataacgat gcggactcag gcgaagctct
      181 tccggcagcg cctgccagag tgcggccagc cggtgacctt catccagttt cgccacaccg
      241 ccgcgcacca gccagagtga ttcgctgcgg ctgtaaccgt cctcaccggg aaacaggtgc
      301 tcaaaataca ggcttctgcc gccgttatca ctgagtatca gtgtgttatc gcgcagctgt
      361 aagcggatat ccgcaggcat tttccagccg gggccgaggc tccccaccgg cgcgggcgtt
      421 tttgtccggt aactgctgta ggtgcgggag agaatgaacg gcagcgggcc gggctgggcg
      481 atgtcggttt caccgggaag gacctttgca cccagcagcg gattgaccgg atggccggac
      541 gtcaccccgc cggggcacac cgaacaggcc acgccggtgg gggcaccaat acgtaccccg
      601 gctgaaccct gaacaatgct accgccatac tgcgtcatgt caccctgacg cgccgccggt
      661 tttccgctca tcgtaaaatc cttttctatt attttaatga cagtatcttc atacgaaaaa
      721 gcgaagaaaa acttgtggtc acaatgaatt gaagattttt aggaatatat ttagaacgtt
      781 acaaaagaga aggttcggat agggtattta gagaggaatc aggtgtgcta gtggcccttt
      841 gttgatcgtt caccaaagga cccaataata gactcaatct tccttcggca agcactgcaa
      901 atgcccgtgc cgcacgccgc gctgggcgat aacgtcatcg gcaaaatgct gcacgtcgcc
      961 catatcacct ttcagcacgg cgatttccag acagtcgtcg tgattgatat gcacatgcag
     1021 cgtggcgacg gagagatcgt ggtgatggtg ctgggtggag acaatgcggc tggctaagtc
     1081 gcgtttttcg tgttcataca cataggagag caccgcgaaa ccttgcgtgc cgtgctgctg
     1141 agtggcctcc tgggccagag cgctacgcag aatatcgcgg atagcttcgg aacgattgtt
     1201 ataaccacga cgctggctca ggctgtccag cgtctccagt aaatcgtcat caagcgtgat
     1261 ggtgactcgt tgcatttgcg ttaaaccttt tctgtggtgc gacggcgcac ggggaatgcg
     1321 ggtaataccg cgttttgtag cacacgtccg gcgtcagagg aaaaggttaa tttatctccc
     1381 accacctggg tttcgacgat ttgtccgttg tccatcacca tcacccgctg acagaagcgt
     1441 tccactaggc gtaagtcgtg ggtgatgaac aggcaggcgg tgccaaactg ttgttgtagc
     1501 tttttcagca ggcgaatgac gcccgcctgt aacacgagat caaggttaga aacggcttca
     1561 tccagaatca gtagtttcgg ttcgaccgcc agcgcgcgag ccaggcagac gcgctggagc
     1621 tggccgccgc ttaactgcgg tgggcgtttg tcgagaacgc tgtcatcgag atcgaccgcc
     1681 ttcagcattt cgctggcgcg cgccagttgt tcggattttt tcagtgatag caggtggcgc
     1741 atcggttcac gcaggatctc gcgcacggtt ttgcgcggat tcacggcgct gatggagtcc
     1801 tgaaatacca tctgaatatc gcggcggaac gctttacgct gggcgcgatt gagtttcgcc
     1861 agcggttcgc cgcgccagct aatattccct tgtgagggag actctaagcc taccagcagc
     1921 cgcgcgaggg tgctttttcc gcagccgctg cgtcccagca gggcgacggt ttcgccgctt
     1981 ttcagggtca gggaaacgtt attcagcacc gcctgatgtt gatgttttcc gctaaatcca
     2041 ccgtgggcat agtgatggga aaggccgcag acgttaagta aggtcatgat gccagctcca
     2101 taccgtagag ggcgagatga gcggaaacca ggctgcgcgt caccgtatgt ttgggggcgt
     2161 taaacagcgt ttctacatcg ccctgttcga caattttacc ttgtgacatc accgccacgt
     2221 catccgccag acgcgccaca acgcccatat catgggtgac cagcagcatt cccggcgctt
     2281 gtttttgcat aatgctttcc agcagatcga ggatgcgcgc ctgtgctacc acgtcgaggt
     2341 cggtggtcgg ttcatcggcg atgataaacg gtgattcaca cagcaccgcc atcgcaatca
     2401 tcatgcgctg caacatgccg ccgctcatct cgaacgggta cagcttcagc acgcgcgcgg
     2461 cgttttccag ccccaccgct tctatggcag cggtaagcgt agcgtcatcg gcgggtttcc
     2521 ctaacgccag gcaggtttcc cgcgcgtggg tgtgcatggt gtgcagtgga ttaaaggcgc
     2581 tgcgcgggtt ctgcatgatg gtggcaattt tgatgccgcg cagggcgcaa ggcgaaaccg
     2641 gtttgccatc ggctaaaatt tcccccgccg tctggcgaac gccagcgggc aaaatgccca
     2701 gcgtcgcggc gcaggttaat gatttcccgc tgccgctacc gccgactaac gccagcacgc
     2761 gcccgcgttg cagggttaac gatacaccgt gtaccagcgg ctgcgcggcc tgtagcgcga
     2821 tattacgtag ttcaatctgt tgcggcatta gtgtgcgtgc tccgtcacca gatgagggtc
     2881 cagatgatcg cgcagtgcgt cacccaccag gttaaaggcc atcacgctga taaacagcgc
     2941 cagccccggc cagaacattt gcagcggctg ggtccagata tactggcgcg cgtcgttaat
     3001 catcacgccc cattcggcgg tcggcgcggt cacaccgagg ccaaggaaag acatccccgc
     3061 gacgtgcagc atcatatggc cgatatccag cgttgccagc accagcagcg aagggatcac
     3121 cgcgcctgcc agatgatcga caaacacccg cacatggccc gcaccggaaa gccgtgacgc
     3181 cagcacaaac tcgcgttggc gtagtgaaat caccaggctg cgcaccatgc gtgcatacca
     3241 cgcccagtgc gacagggcga tggcgataat tacgttggtc agcccggtgc cgagcacgcc
     3301 aaccataaag aacgacagaa tcgaggtcgg gaaggtcata aacatatcgg cgacgcgcat
     3361 ggtggcctga tcaacgcgcc cgccaatcaa cccggcgctg ccgccaataa ccagccctaa
     3421 tgtcagcacc agcagcaggc aggccattac cgaaccgagc gacacgcggg tcgccgccat
     3481 cagccgcgag aaaatatcac gccctaagtg atcggtgccc agccagtgct gcgcatccgg
     3541 cgaaagcagg cgcgacggca gatcaatagc ctgagggtca tacggcagcc accactggct
     3601 ggtaagcgca atcagcgcca gcagggcgat aatgatcagc gccaggcgta ccgaccagcg
     3661 ggaagagagg aaaaagttca cgcgtgcgct ccttcatgac gacgaatgcg cgggtccagc
     3721 gcggcgttga gcaaatcgac aatcaaatta cagaccacaa aaaccaccac catcatcagc
     3781 gtaaagcact ggatcaccgg atagtcacgg ttaaaaatcg ccgacaccgc atagcgcccg
     3841 acgcccggcc aggcaaagat gttttcgata atcatcgtcc cgccgatcag ttcgccgatg
     3901 tgcatcccca cggcggtgat catcggcagc gaggcattgc gcaggatgtg gcgacgttcg
     3961 gtctgtttgt cgttcaggcc gcgcagacgc gcccaggtga cgtgacgctg accggcgacg
     4021 tccagcatac tggcgcgcag taaacgcgcg ttaatcgcca gcgacataaa ggcaatggaa
     4081 accgcaggca aaatgatgtg ctgccagccg ccgtaaccca tcgcgggtag ccattgcaga
     4141 tacaccgaaa acgccatcac cagtaaaaac gccagccaga agttaggcat cgacacgcca
     4201 agaaacgcga tgaaacgtac ggcgaaatcc ggcagacggt cgcggtggcg cgccgcccag
     4261 ataccgagcg gtacggaagt gagcagaatt aataccagcg ccgcacctgc aagttccagc
     4321 gtggcgggca ggaagttcag catatcgtcc agtaccgggc gttggctggc gaatgagata
     4381 ccaaagtcaa gatgcagcgc cttccacaac caggtgccgt actggacgta cagcggctga
     4441 tccagtccca gcatggtgcg ggtagaggcc agcatctccg gcgtcggcgg caggttagac
     4501 agacgcaaat aatcgagcgc cgggtcgccg gtaccgaggc gcagcatcag aaaaatgatc
     4561 accgaggcgg cgagcaccat cgggatcagc agcagaaagc ggcgtaatac gtaacgcaac
     4621 attaaggttt caccggttta atctgttcga acggaatttc ggtggcgatc ggcgcgtagg
     4681 ggatgttacc cagctccggt tttgatacca ccatcatcga gatgtagctg ataggcagat
     4741 aaaccgcctc gtcatgcaga cgggtcagaa tgtcgcgata cagcgcctga cgttgcgttt
     4801 cgtcatgggt cgccagcact tcgccgatct ctttatcaat cagcggcttg tcggctaatc
     4861 cttgctgtgc ctggaagtca gcgtgcgacg gtacgcgcat tgaactcagg aaggcgtgtg
     4921 gatcgtatgg cgcgccccag gtgcggtgga aaatcatgcc aaaacgaccg tcgcgctgac
     4981 gagcatagat actgctctct tcttcgccaa tcagcgagac atctgcgcca atctggcgca
     5041 tatcagcctg aatgatttcc gccatcgatt tgcttaacgc atcggtgccg atgaacgaca
     5101 gttcaatgcg cagcggctga ccatttttct cgcggatgtc tttgcccgca ggcagcgtcc
     5161 aaccggcttt ttccagcaac tctttcgctt tctgcggatc gtactggcgc ggtttcaggc
     5221 cgagattagc gtaaggcaca gaaggggcaa acagggtgtc ggcgacctgc tgggtgccat
     5281 ataacgcgtt atcaatcagc gattttttgt ttaccgcgta attaagagct tcacgtactg
     5341 ccagctcgtt ggtgggggct ttggcggtat tgagcgccag catcacggtt tcgatcggct
     5401 gtgacagttg ggtgtggtaa gccggattct ggctaaagcg ggcgaaggta tcgagcggta
     5461 ataacccttc gtttccgtac agcaggtcga tatcgccagt ttcaaacgcc accgcgcggg
     5521 tagtcgggtc cgggatgacg ttaaaggtga tctttttaat cgctggcttt tcgccccagt
     5581 agttttcgtt acggacgaag acatcgtact gattcagttt cgattcctgc aaaatccacg
     5641 gtccggtgcc aatcggcgct ttaattccgt tcatggtttc atggttttta aactgcgagg
     5701 gagcgataaa acggaaagga cggggcaggg ccagttcttg caggaaagga tagtaggcgc
     5761 ttttcagggt aatttgcagc tctgttttac tgagtgcttt aacatcaaca atctggtttg
     5821 ccagctccag ccaggcgtga cgttgacggt tatcgagcac tgcgcggaag ttttctgccg
     5881 ccgcctcggc atcgaacggt tcaccgttgg agaatttcac gtcatcacgc agggtgaagg
     5941 tccaggtttt accatcttct gaatgagtcc agctttttgc cagccacggg atcaccgaac
     6001 cgtctgcctg atatttcacc aatggttcat aaaccatgct ctgggcgaac atctggttag
     6061 gcgtgtaaag gtgcgggttt agtggcccga cattcaccgg ccaggcggtg gtgatttcat
     6121 ctggtgcagc ggcatggacg ataaaagacg cacaagccag cagcgcaaat agagtgcggc
     6181 ggagtgtgga gagcatggta accccaatgg attaaaatag atggcggaaa taagtatgac
     6241 gattttaagt attcgtcata ctgattacct gttctggatc aatagatggg cagtcgggtg
     6301 ggcggatcag ttaactgaat cgatccattg cacactgtcg gcggtgagcg taaagggggt
     6361 gggggtgcag atcgccaggc ttaaattttc aagctgacaa tggctgactg acagcgagga
     6421 gtgataggtg ctgtctacgc tgacgatttg ccaggcgctg ccgccacgct gtttaacgat
     6481 ggcttctttg cgcgtccaga tgcgccagaa catttccagt tgctgatcag gatgcacggc
     6541 gtccatctca gcgtgttccc cgaggctgaa tacggcgttc gccagccagc gccagttggc
     6601 gcgcgggcga atcacttcga tatcgcagcc gacttcgcct tcatcactca acagcagagc
     6661 gatatcgtca ccgctatggc ttaagttgaa ccatagcggc gtttccggcg cgaatgcagg
     6721 tttgccttgt tcgccataga tgatctccgg tagcggggaa agcgtgtgcg aaagcaatgc
     6781 acgccccgcc agccagcgtt cgcgtcgtgg accttgcggt gcttgctcgc gtaaacccgg
     6841 tggcagtgga gctgcgctta aggtcgaaac tttccccaga actatccgat acatatcagg
     6901 gccaacgttt aatggaaaat gaaagtgcgt atcgtatcac ttgtcgcctc atcccggtaa
     6961 ccgacttttc ggtctgcccg gccccagtaa aatcgccagt ttgctgccac ctttcgtcgt
     7021 ttccatccag attttacaca cgctggttaa tggcaccgaa agtagcatcc ctaccgggcc
     7081 gagcagccat ccccagatta acaatgaaag aaataccacc atggtggaca tccccaggcg
     7141 atggcccatc atccgtggct ctaaaatatt gccgatgacc atatggacaa ctaaaaacaa
     7201 tgcgccgacc agaatacatt cgtaaatacc attaaacagc agcacctgaa tcattggcgg
     7261 tacggcggaa attaccgcgc cgatattggg cacgtagtta agcaaaaacg ccagtactgc
     7321 ccacatcagc gcaaactgta cccccatcag ctccagcccc agccagacga tgacacctgt
     7381 ccataaactg agtagcgtct tcaatgcaag atagtgcgaa acgcctttaa gtgcgcggtg
     7441 taatcccgcg atgtgaatct gtggattatt cagcgcaaaa cgcattttgt aagggacgtg
     7501 gcgcacttca aacagcataa aaactacggt catcaccagc aaaagcacgc tcgccattgc
     7561 cccggaaagc ccggtcatta gcgctgtggt gaaggtaacc actttttccg agtccatccg
     7621 ctgcagcatt cgctccggcg acatatgcaa attaagaaaa ggcaacatct cctgcaattt
     7681 aaaaagtttg cgcgtcagct ccttattaaa cttcggcagc atagagataa attcgttaaa
     7741 cgatgccgcc agtacgccga ccagcgcggt tagtgcgatc agcatcacca ccactacaat
     7801 cgtaatggca acggggcgtt gtactccccg acgaataaac caggtgacga gcgggttgag
     7861 gacgatggca aaaaacagcg ccagtaacag ctgcacaatg atatctgccg ctgcgtgaat
     7921 gcccgcgagg atcactacca gcgaggccag cttgagcaga atgtgcatgc ccgttttatc
     7981 gggttgaggg gtttccattg gggcttcctt gtgacttttt gtattaagtg tagcgggagt
     8041 cacgccagca atattctgat tcttactgct gattttcacg tcagcacatg gtaaaaatga
     8101 aacactgttg taaaaatgtg gtgatcctca tgcccgaacc cgtagccgaa cccgcgctaa
     8161 acggattgcg cctgaatttg cgcattgtct ccattgtcat gtttaacttc gccagcaacc
     8221 tcaccatcgg gttgccgctc gctgtattac cgggctatgt ccatgatgtg atgggcttta
     8281 gcgctttctg ggcaggattg gttatcagcc tgcaatattt cgccaccttg ctgagccgcc
     8341 ctcatgccgg acgttatgcc gatttgctgg gacccaaaaa gattgtcgtc ttcggtttat
     8401 gcggctgctt tttgagcggc ctggggtatc tgacggcagg attaaccgcc agtctgcctg
     8461 tcatcagcct attattactt tgcctggggc gcgtcatcct tgggattggg caaagttttg
     8521 ccggaacggg atcgaccctg tggggcgttg gcgtggttgg ctcgctgcat atcgggcggg
     8581 tgatttcgtg gaacggcatt gtcacttacg gggcgatggc gatgggtgcg ccgttaggcg
     8641 tcgtgtttta tcactggggc ggcttgcagg cgttagcgtt aatcattatg ggcgtggcgc
     8701 tggtggccat tttgttggcg atcccgcgtc cgacggtaaa agccagtaaa ggcaaaccgc
     8761 tgccgtttcg cgcggtgctt gggagcgtct ggctgtacgg tatggcgctg gcactggctt
     8821 ccgccggatt tggcgtcatc gccaccttta tcacgctgtt ttatgacgct aaaggttggg
     8881 acggtgcggc tttcgcgctg acgctgttta gctgtgcgtt tgtcggtacg cgtttgttat
     8941 tccctaacgg cattaaccgt atcggtggct taaacgtagc gatgatttgc tttagcgttg
     9001 agataatcgg cctgctactg gttggcgtgg cgactatgcc gtggatggcg aaaatcggcg
     9061 tcttactggc gggggccggg ttttcgctgg tgttcccggc attgggtgta gtggcggtaa
     9121 aagcggttcc gcagcaaaat cagggggcgg cgctggcaac ttacaccgta tttatggatt
     9181 tatcgcttgg cgtgactgga ccactggctg ggctggtgat gagctgggcg ggcgtaccgg
     9241 tgatttatct ggcggcggcg ggactggtcg caatcgcgtt attactgacg tggcgattaa
     9301 aaaaacggcc tccggaacac gtccctgagg ccgcctcatc atcttaaaac ttactgaata
     9361 accagcgtat taatgatgtt ttctgcggtg gtctgcgctt tttgctgatc gtcagcgggc
     9421 agcgtaattt gcatggtcag cagttgatta cccacgttac ccagaataac ggaagagtac
     9481 gccgtctggc ctttcgcgga gataatactg tctaactgct gcattttgtg acctttcagc
     9541 tcaatggctt tattggttac cacttgcagc tgcggatcgc ggctacgttg ctgatcttcc
     9601 agacgcttcg ccagcaccgc cagatcttct ttcggatcat cgcccatgat gacgatgact
     9661 gctttctgcc cggtggcgtc ggaccagaca tgcatgttat tggcctgcgt tcccagctta
     9721 ccgctctggt cggtcatatc cgctggcagc gagaaactta acttgccatc aagcaggttg
     9781 acgggattcc cggtagcgtt actttccgcg accgaaccct gcgccgtagc gttagtgtct
     9841 ttatcatcac aggccgcaag ccccataacc agcaggccaa ttccgacata tttaaccaga
     9901 ttgcgcattg acttcttcct ttcgataaac ggccataacg gctcattcat ccatcttatc
     9961 acaactctga taacgaacct ttaactcgcc tgcaaagcgt tgatttcgga tttatctgcc
    10021 agtcttttca acagcatatt gagtaatacg ccatacattg gcaggaagaa aacgatactg
    10081 attaacactt tgaaacagta atcgaccagc gcgatttcca tccagtgttc agccataaag
    10141 gcatccgggc tacgccagaa ggcaatgaag aaaaaggcca gcgtgtcact gacgttaccg
    10201 aacagtgtgg acgctgtcgg tgccagccac cagcggcgac tttgacgcag gcggttaaaa
    10261 acgtgcacgt cgaggatttg ccccagcgcg taggccatga aactggcggt ggcgatacgg
    10321 gcgacaaaca ggttgaagtg ggcgagtgcg ccgaatccct gccaggaacc catatagaat
    10381 agcgacgaga tgacgtagga gattaataac gcagggatca ttaccgcgaa gataatgcgt
    10441 cgggccagcg gtgcgccaaa aatacgcacg gtcaggtcgg tagcaagaaa aataaacgga
    10501 aagctaaacg cgccccaggt ggtatggaaa cccaaaatgg agacgggaag ctgaaccaga
    10561 tagttactgg aggtgatcac cagcagatga aataacgata accagaacaa cgccttatag
    10621 cgttgagttt gcgagaaaac gttcatattg tacctttttg attaaccatt ggggtgaggg
    10681 aacccaatac gtacgacacg tctgttacct taacataata acgtgcttac ccttttttcg
    10741 agccgccgca tgatactgct ttacgttgac aatgcaatgg ttaattttca cgcaatcgtt
    10801 aacctagttt gcttacggac tcacagggcg taaactagcg ccgttttttt aagtgatgag
    10861 aagaaaatga ccgatctctt ttccagccct gaccacacac tcgacgcgct tggcctgcgc
    10921 tgcccggaac cggtgatgat ggtgcgcaaa accgtgcgca atatgcagcc tggcgaaacg
    10981 ttgctgatta tcgccgacga tccggccact acccgcgata ttcctgggtt ttgtaccttt
    11041 atggaacacg aactggttgc taaagagacg gatggactgc cttatcgtta tttgattcgt
    11101 aaaggcggtt gataggggct gattggcttc gatgccgcct tttcccctca ccctaaccct
    11161 ctccccagag gggcgagggg accgatcgcg ctcaatgttg cgatcggttt gccttatctc
    11221 ctgcgcaaca atcttaacgc attcgctgtc accagcaccg tcgcccccgt atctgccagc
    11281 actgccagcc acaacccggt catccctaac agcgtggtga cgaggaagat ccctttcagc
    11341 cccagcgcaa tagtgatgtt ctggcggata ttggcgtgag tggcgcgtgc cagttcaatc
    11401 atttgcacca ggccgcgcag gtggttatgg gttaatgctg cgtcggcggt ttccagcgcc
    11461 acgtctgtgc cgctacccat tgcaatcccg atggcggcag ctttcatcgc tggcgcgtcg
    11521 ttaataccgt caccgaccat cgccagcggc gcatgttgat tcagctcggt caccgctttg
    11581 actttatctt ccggcaacag gcccgcttta aactccagcc ccagctcccc ggcaattgcc
    11641 gccgctgcgc gtggattatc gccggtgagg atcacccctt tgacgcccag cgcgttcagt
    11701 tcactgatgg cagttgcagc atcggcgcgc agggtatcct gtaacgcaat gatacccagc
    11761 acgtcatcgt tacgtactac cagcactacc gtttgcccgg cgctttccag ttcgttaatt
    11821 aaaccagtaa atgcatcagc gggatgtttc ccggcagcgc aaatcaatac gcgctcaccg
    11881 ttaacctgcg cttcaatgcc agacccgacc agcgcccgct gtgattcggc ggtgggaatg
    11941 gcgagttcag caacctgtgc ttcgcgtacg atggcttgcg ccagtggatg cgtcgcgcct
    12001 tgctcgaccg ccgccgccag tgtcagcagt tcagattcac taatacccgt tgccggatga
    12061 atcgcggtaa cgcgcggttt accgacggtc agcgtaccgg ttttatcaaa cgccacctga
    12121 gtaacacgac ccagctgttc cagcgccgct ccgcctttaa tcaacgcccc acgacgcgct
    12181 gccgccgcca gcccggaggt aatcgccgca ggcgttgaga taactaacgc acacgggcag
    12241 ccaatcagca gcagcgtcag ccctttataa atccactcct gccagctggc ggcaaacagc
    12301 agcggtggca ccagcgtcac cagcagagcg acggccataa tcgcgggcgt atagatacgg
    12361 ctgaaacggt cgataaaccg ctcaatggga gcgcgacgct cttcggcttc ttcgatcagt
    12421 ttcagaatcc ggtcaatggc gctggctccc ggttctgaca gcacttccaa cgtcaccaga
    12481 cggtctacgc tggtggcacc agcagggact ttatcgcccg ttgcgcgctc caccggaatg
    12541 gattcgccgg tcagggcgct ttcatcaaaa ctggcaaacg gtgagagcag tttaccgtcg
    12601 gcaggcaaac gcccacctgc ggcgacttca atcacatcgc cagggcgcag gctgttaatc
    12661 gccacctctt cccgctcacc cttacgcagg cgcgtggcgg tttctggttt cagcgccatt
    12721 aacgcgctaa cgccctgacg cgcgcggctg gcggcccagc cttccagtcg ttcaccaatc
    12781 aaaaacagca gcaacaccat cgcagcttca gccgttgcgc caataaacag tgcaccaata
    12841 gcggctacgc tcattaaggt ttcaatggcg aagtagctgc cggatttgat cagccgtaat
    12901 gcctgacgag caatcgggta cagcccaacc agcgtggtcg cgataaacgc cagttgccca
    12961 aacggatgat taaattgctc cagaccccag ctgattgcca tcatcacgat tagcgtaatc
    13021 agcggcagat tctctttcag gcgcgatgct tgtggctcgt cggcggcctg ctcatcgcgc
    13081 agggaatagc ccgctttttg caccgcagat tcaacctggg cacggatgtc attgtcggca
    13141 tcgaccacca gtttttcggt ggcgaacagt acctgcacct gattcacacc tgcaagctgg
    13201 cgcacggcat tttctacctt gcgcgcacag gcggcgcagt ccatgccgct gactttccag
    13261 ctatagcggg tgccggagac gttttcagag agcgttggcg agctggaaca tgcgccgtcg
    13321 cagcaacagt cgttggcgtt ctgtaccgtg gttagcggtt tgaacgcagc aaattgaggg
    13381 gctttcttgc cgtgattgtc aggagtcgac atggcatcct ccggttaagt tttttctcat
    13441 taaccgaagg atacactctg gagtcgactc cagagtcaag ttttatcaga gatacagcga
    13501 gcggacgatg aggaaatgac cggcaaagta gcaggccgca gcaatcgcgt tatctgcccg
    13561 gaagcggcgg cgatagtggc tacccagcca gacaaagtta ctgataaaca gcaatgaagc
    13621 gccaacaaac gcagagagtg ccggagcggt cggacggaag aaccacagtt cacctgccag
    13681 ccacaccatc accagcgtca tgccgataaa cgtgcagata ggccaacgat actcttccag
    13741 ccgcgtccag ataatcgcca gtaacagcgc gcccagaacc agcaacacca gtggcagagg
    13801 ccagaagaaa gagagcgtca tctgactggc gaaatagatg gtgtacagca ggtgcgagag
    13861 gaaaaacgcg ccgatggcgt acatcagacg ttgacgtggc aacagggtta gcgcatcgcc
    13921 cagcagtgag gcgcacagcc ctgccagcac cagatagcta atggcgtcga acatcggcgc
    13981 ttgccaggcc agtaacagca ggagaagaag ggttaacggt ttaaacaccc agcgttgcca
    14041 ggttggccca cgatacgatg catccacaga tagccatgcg gaaagacaga cagcgataaa
    14101 cgaccaaagc atcttagttc cttgaattcg ttattttttc gtaagcggaa tgcctacggt
    14161 cttgcttcca gtttagtggc gagggtggac ggatgacaac accataactg gcagggtatg
    14221 cttatttccg cattttccga tgagggataa agatgagcaa accacctctt ttctttattg
    14281 ttatcattgg cttaattgtc gtcgccgcat cgtttcgttt tatgcaacag cgacgggaaa
    14341 aagctgataa tgatatggct ccgctccagc aaaagctggt ggtggtgagc aacaagcggg
    14401 aaaaaccgat taacgatcgc cgttcgcgcc agcaggaagt gactccggca ggcaccagta
    14461 tgcgctatga ggcaagcttc aaaccgcaaa gcggaggaat ggagcagacg tttcgcctcg
    14521 acgcccagca gtaccacgcc ctgacagtgg gcgataaagg tacgctgagc tataaaggaa
    14581 cgcgctttgt cagctttgta ggcgaacaat aaggttattt tttaacttta aatttcttct
    14641 gccagaccag cagttcaaac acgccgaaaa ggaaaatccg caccttttcg gcggtggtca
    14701 tctgcgggcc atctttcggt aaagtggatt tcaatagcgc cagctgcata ccatgcatca
    14761 gcacggtaaa aatcagcgcc acgttaacga aaatattcag cgggcgcggg aagggatgca
    14821 ccagattgag gattaaaaat ccccaaacgc agagcattaa caaacgacca atattaatca
    14881 gcatcacttt ctccttgtgc ttcgcgttga tacagccgat aagccacctg acccgccact
    14941 ttttcccgat gtaatgacca gtttgccgga acagtgggca gaccgttttc gacttcgctt
    15001 tcgacataaa tcagggcttc gtcagccagc cagccgttat cttccagtaa atttatcgtc
    15061 tcttctaaca agccacggcg gaacggtgga tcgacaaaca cgatattatg cggtgtgcct
    15121 ttttgcgcca ggaatgacat tgcgttgctg ttcaccacgc gtgcattgcc tgcttttagt
    15181 gtcgccagat tcttaattaa ctgctgagaa accgcgcgat ccatctcaat caacgtggcc
    15241 cccgcagcat agcgcgacaa cgcttccagc cccagcgcgc cgctcccggc gaagcaatcc
    15301 agacattggg cgtcaacaat gaccggagcc agccagttaa acaacgtttc gcgtacgcgg
    15361 tcggtggtgg ggcgcagacc tgggctatca ggaaccggga gtttacggcc tcgccactgc
    15421 ccgccaataa tgcggatttg gccgctgccg gaatgattcg gttttttcat gataaattgc
    15481 tcaatccgcc agataacaca tacttgcagg cggtgatgtg aattaagtta agtgatagac
    15541 tatttcatca tttttttagc tgctatgtac atagcgttaa cgctgtgcca tgaagcaaca
    15601 gcgaggagtg tagtcgcaaa tggcgaaaga aaaaaaacgt ggcttttttt cctggctggg
    15661 ctttggtcaa aaagagcaga ccccggaaaa agagacagaa gttcagaatg aacaaccggt
    15721 tgtagaagaa atcgttcagg cgcaagagcc tgtgaaggcc tctgaacaag ccgttgaaga
    15781 gcagccgcaa gcgcatactg aagccgaggc ggaaactttt gctgccgacg ttgtggaagt
    15841 cactgaacag gttgctgaaa gtgaaaaagc gcagcctgaa gcggaagtcg ttgcacagcc
    15901 ggaaccggtc gtagaagaaa cgccggagcc agtggctatc gaacgtgaag agctgccgtt
    15961 gccggaagac gtcaacgccg aagcggtttc gccagaagag tggcaggctg aagcggaaac
    16021 cgtagagatt gtcgaagcgg cggaagaaga agcggctaaa gaagaaatta ccgacgaaga
    16081 gctggaaacg gcgctggctg ccgaagcggc agaagaggcg gtgatggtgg ttcctccggc
    16141 agaagaagag cagccggtgg aagaaatcgc tcaggagcag gaaaaaccga ccaaagaagg
    16201 ttttttcgcg cgcctgaaac gcagcctgtt aaaaaccaaa gaaaatctcg gttccggatt
    16261 tatcagcctg ttccgcggta aaaaaatcga cgatgatctg tttgaggagc tggaagagca
    16321 gcttttgatc gccgatgtgg gtgtggaaac cacacgtaaa attatcacca atctgacgga
    16381 aggcgcatcc cgcaagcagc ttcgtgacgc cgaggcgctc tatggcctgc tgaaagaaga
    16441 gatgggcgag attctggcga aagtcgatga gccgctgaat gttgaaggca aagcgccgtt
    16501 tgtgatcctg atggtgggcg tcaacggtgt gggtaaaacc acgacgattg gtaagctggc
    16561 gcgtcagttt gagcagcagg gtaaatcggt gatgctggcg gcgggtgata ctttccgtgc
    16621 agctgcggtt gaacagcttc aggtctgggg tcagcgcaac aatattccgg tgattgccca
    16681 gcataccggg gcggattccg cctctgttat cttcgacgcc attcaggcag ctaaagcgcg
    16741 taatatcgac gtcctgattg ccgatacagc cggacgcctg cagaacaaat cgcacctgat
    16801 ggaagagttg aagaaaatcg tccgcgtgat gaagaaactc gacgttgaag cgccgcatga
    16861 agttatgctg actattgatg ccagcaccgg gcagaacgcg gtaagccagg ccaaactgtt
    16921 ccatgaagcc gttggcttaa ccggcatcac gctaacgaaa ctggacggca cggcgaaagg
    16981 cggggtaatt ttctcggtgg ctgaccagtt tggtatccct atccgctaca ttggtgtcgg
    17041 cgaacgtatt gaggatttgc gtccgtttaa ggcggacgac tttatagagg cactttttgc
    17101 ccgagaggat taacaatgat tcgctttgaa catgtcagca aggcttatct cggtgggaga
    17161 caggcgctgc agggcgttac gttccatatg cagccgggtg agatggcgtt tctgaccggt
    17221 cattccggcg cagggaaaag taccctcctg aagctgatct gtgggattga gcggcccagc
    17281 gccgggaaaa tctggtttag cggccatgac atcacgcgtc tgaaaaaccg tgaagttccg
    17341 tttctgcgcc gccagattgg catgattttc caggatcacc atctactgat ggaccgtact
    17401 gtctacgata acgtggcgat cccgctgatt atcgccggtg ccagcggtga cgatattcgt
    17461 cgccgggtgt cggcggcgct ggataaagtc gggctactgg acaaagcgaa gaacttccct
    17521 attcagcttt cgggcggtga acaacagcgt gttggcattg cccgcgcggt ggtgaacaag
    17581 cccgcggtac tgctggcgga cgaaccgact ggtaacctgg acgacgcgct gtcggaaggc
    17641 attttacgtc tgtttgaaga gtttaaccgc gttggggtaa ccgtattgat ggcaacgcac
    17701 gacatcaacc tgatctcgcg gcgttcctat cgcatgctca ccctgagcga tggtcacttg
    17761 catggaggcg tgggccatga ataagcgcga tgcaatcaat catattcggc agtttggcgg
    17821 gcgtcttgat cgcttccgta aatcggtcgg cggctcaggc gacggcggtc gtaacgcacc
    17881 aaaacgcgcg aaatcctcgc caaaaccggt aaatcgcaaa accaacgttt tcaacgaaca
    17941 ggtgcgctat gccttccacg gcgcattgca ggatctgaaa agcaaaccgt tcgccacgtt
    18001 tttaacggtg atggttatcg ccatttctct gacgctgccc agcgtctgtt atatggtgta
    18061 caaaaacgtt aaccaggcgg cgacgcagta ttatccgtca ccgcaaatca ctgtttatct
    18121 gcaaaaaacg ctggacgatg acgctgctgc gggcgtggtg gcacagttgc aggccgagca
    18181 aggcgtggag aaagtgaact atctttctcg tgaagacgca ctgggtgagt tccgtaactg
    18241 gtctggtttt ggtggtgcgc tggatatgct ggaagaaaac ccgcttccgg cagtggcggt
    18301 ggtgatcccg aaactcgatt tccaggggac ggaatcactg aatacgctgc gtgatcgtat
    18361 cacgcagatt aacggcattg acgaagtgcg gatggatgac agctggtttg cccgtctggc
    18421 ggcgttgacc gggctggtcg ggcgcgtttc ggcgatgatc ggcgtgttga tggtggcggc
    18481 cgtgttcctc gtcatcggta acagtgtgcg tctgagtatc tttgctcgcc gtgactccat
    18541 taacgtacag aaactgattg gtgcgacaga tggattcatc ctgcgcccgt tcctgtatgg
    18601 tggcgcactg ctgggatttt ctggcgcatt gttgtcatta attttgtcag aaattctggt
    18661 gctgcgattg tcatcggcgg ttgcggaagt ggcacaggtt ttcggaacga agtttgatat
    18721 caatggctta tcattcgatg aatgcctgct attgctgctg gtatgctcga tgattggctg
    18781 ggtggcagcg tggcttgcca cggtacaaca tttacgccac tttacgcctg aataataaaa
    18841 gcgtgttata ctctttccct gcaatgggtt ccgtagcagg gaaagagacc ccgttgtctc
    18901 ttcccggtat ttcatctcta tgtcacattt tgtgcgtaat ttattcacaa gcttgcattg
    18961 aacttgtgga taaaatcacg gtctgataaa acagtgaatg ataacctcgt tgctcttaag
    19021 ctctggcaca gttgttgcta ccactgaagc gccagaagat atcgattgag aggatttgaa
    19081 tgactgacaa aatgcaaagt ttagctttag ccccagttgg caacctggat tcctacatcc
    19141 gggcagctaa cgcgtggccg atgttgtcgg ctgacgagga gcgggcgctg gctgaaaagc
    19201 tgcattacca tggcgatctg gaagcagcta aaacgctgat cctgtctcac ctgcggtttg
    19261 ttgttcatat tgctcgtaat tatgcgggct atggcctgcc acaggcggat ttgattcagg
    19321 aaggtaacat cggcctgatg aaagcagtgc gccgtttcaa cccggaagtg ggtgtgcgcc
    19381 tggtctcctt cgccgttcac tggatcaaag cagagatcca cgaatacgtt ctgcgtaact
    19441 ggcgtatcgt caaagttgcg accaccaaag cgcagcgcaa actgttcttc aacctgcgta
    19501 aaaccaagca gcgtctgggc tggtttaacc aggatgaagt cgaaatggtg gcccgtgaac
    19561 tgggcgtaac cagcaaagac gtacgtgaga tggaatcacg tatggcggca caggacatga
    19621 cctttgacct gtcttccgac gacgattccg acagccagcc gatggctccg gtgctctatc
    19681 tgcaggataa atcatctaac tttgccgacg gcattgaaga tgataactgg gaagagcagg
    19741 cggcaaaccg tctgaccgac gcgatgcagg gtctggacga acgcagccag gacatcatcc
    19801 gtgcgcgctg gctggacgaa gacaacaagt ccacgttgca ggaactggct gaccgttacg
    19861 gcgtttccgc tgagcgtgta cgccagctgg aaaagaacgc gatgaaaaaa ttgcgtgctg
    19921 ccattgaagc gtaatttccg ctattaagca gagaaccctg gatgagagtc cggggttttt
    19981 gttttttggg cctctgtaat aatcaatttc ccctccggca aaacgccaat ccccacgcag
    20041 attgttaata aactgtcaaa atagctattc caatatcata aaaatcgggt atgttttagc
    20101 agagtatgct gctaaagcac gggtagtcat gcataaaacg aaataaagtg ctgaaaaaca
    20161 acatcacaac acacgtaata accagaagaa tggggattct caggatgaac ataaagggta
    20221 aagcgttact ggcaggatgt atcgcgctgg cattcagcaa tatggctctg gcagaagata
    20281 ttaaagtcgc ggtcgtgggc gcaatgtccg gtccggttgc gcagtacggt gaccaggagt
    20341 ttaccggcgc agagcaggcg gttgcggata tcaacgctaa aggcggcatt aaaggcaaca
    20401 aactgcaaat cgtaaaatat gacgatgcct gtgacccgaa acaggcggtt gcggtggcga
    20461 acaaagtcgt taacgacggc attaaatatg tgattggtca cctctgttct tcatcaacgc
    20521 agcctgcgtc tgacatctac gaagacgaag gcattttaat gatcacccca gcggcaaccg
    20581 cgccggagct gaccgcccgt ggctatcagc tgatcctgcg caccaccggc ctggactccg
    20641 accaggggcc gacggcggcg aaatatattc ttgagaaagt gaaaccgcag cgtattgcta
    20701 tcgttcacga caaacagcaa tacggcgaag gtctggcgcg agcggtgcag gacggcctga
    20761 agaaaggcaa tgctaacgtg gtgttctttg atggtatcac cgccggggaa aaagatttct
    20821 caacgctggt ggcccgtctg aaaaaagaga atatcgactt cgtttactac ggcggttatc
    20881 acccggaaat ggggcaaatc ctgcgtcagg cacgcgcggc agggctgaaa actcagttta
    20941 tggggccgga aggtgtggct aacgtttcgc tgtctaacat tgcgggcgaa tcagcggaag
    21001 ggctgctggt gaccaagccg aagaactacg atcaggttcc ggcgaacaaa cccattgttg
    21061 acgccatcaa agcgaaaaaa caggacccaa gcggcgcatt cgtttggacc acctacgccg
    21121 cgctgcaatc tttgcaggcg ggcctgaatc agtctgacga tccggctgag atcgccaaat
    21181 acctgaaagc gaactccgtg gataccgtga tgggtccgct gacgtgggat gagaaaggtg
    21241 atctgaaagg ctttgagttc ggcgtatttg actggcacgc caacggcacg gcgaccgatg
    21301 cgaagtaatc attaatcggc aactttgggt tgccgccaaa ttgctaatat cgagtacgtt
    21361 gcttcatgcc ggatgcggcg taaacgcctt atccggccta caagatccaa agaaatcagt
    21421 aaattgcaac acacattgta ggcctgataa gcgtagcgca tcaggcaatt tctcgttggt
    21481 catcactttt gaaatcaact tgacgattaa cgcttctccc agccgccctg ttgcgccgta
    21541 aaccccagcg cctgcataaa cgccgtcatc acaccgcgat cttccacgcc tgcatccgcc
    21601 atccaccagc atgaaacggc aggattgtta cgcaaaacct cttccagcag atattgcccc
    21661 acaccgcgac ggcgggtgac ttcccgcacg cgcagggaat ccagtgctcc ctcggtgccg
    21721 cttaaggtta cccgcacggc cgctagcagg cgctcgttaa aacgcgcggc gtagatgcgg
    21781 tggttatcgt caacctgtaa agaggaaggg gaatactccg gccagatctt ttgcaggtca
    21841 atccggtcct ggtcgctaaa gttttctaat cgaatgatgg tcagcttcat ggggaacccg
    21901 tgtaaatcac aaaagtggaa ccagtgtagc gaaataattt aatcggaggc tttctctttt
    21961 ttatttcttt tggcaggtga ttaatttttt aacagcaata attacaaagt taaaacatta
    22021 gagaatgaaa aatacccagc ataatcccct gaatggtagt gaattattcc gctctttgta
    22081 ccgttatttt atgctgacaa cggcgctttt ttctgtttat ctatcaataa attcagaata
    22141 ttatctgttc ttaatcgact gaaaaatagg gattttaatc gctattatca caaaatactg
    22201 cgctaaaccc ttaatcagac aggcaaaaac agtgcagtat aaaaaaagaa cagtctgatt
    22261 tgttaacaca taaaaacaaa gcaacacaac atcacgaatg gggatttttg actatgaaac
    22321 ggaatgcgaa aactatcatc gcagggatga ttgcactggc aatttcacac accgctatgg
    22381 ctgacgatat taaagttgcc gttgtcggcg cgatgtccgg cccgattgcc cagtggggcg
    22441 atatggaatt taacggcgcg cgtcaggcga ttaaagacat taatgccaaa gggggaatta
    22501 aaggcgataa gctggtgggc gtggaatatg acgacgcctg cgacccgaaa caagccgttg
    22561 cggtcgccaa caaaatcgtt aacgacggca ttaaatacgt tattggtcat ctgtgttctt
    22621 cttctaccca acctgcgtca gatatctacg aagacgaagg tattctgatg atctcgccgg
    22681 gagcgaccaa cccggagctg acccaacgcg gttatcaaca cattatgcgt actgccgggc
    22741 tggactcttc ccaggggcct acggcggcaa aatacattct tgagacggtg aagccccagc
    22801 gcatcgccat cattcacgac aaacaacagt atggcgaagg gctggcgcgt tcggtgcagg
    22861 acgggctgaa agcggctaac gccaacgtcg tcttcttcga cggtattacc gccggggaga
    22921 aagatttctc cgcgctgatc gcccgcctga aaaaagaaaa catcgacttc gtttactacg
    22981 gcggttacta cccggaaatg gggcagatgc tgcgccaggc ccgttccgtt ggcctgaaaa
    23041 ctcagtttat ggggccggaa ggtgtgggta acgcatcatt gtcgaatatt gctggcgatg
    23101 ctgccgaagg catgttggtc actatgccaa aacgctatga ccaggatccg gcaaaccagg
    23161 gcatcgttga tgcgctgaaa gcagacaaga aagatccgtc cgggccttat gtctggatca
    23221 cctacgcggc ggtgcaatct ctggcgactg cccttgagcg tactggcagc gatgagccgc
    23281 tggcgctggt gaaagattta aaagctaacg gtgcaaacac cgtgattggg ccgctgaact
    23341 gggatgaaaa aggcgatctt aagggatttg attttggtgt cttccagtgg cacgccgacg
    23401 gttcatccac ggcagccaag tgaaaatccc accgcccgtg aaaaacgggc gggtttagaa
    23461 aggttacctt atgtctgagc agtttttata tttcttgcag cagatgttta acggcgtcac
    23521 gctgggcagt acctacgcgc tgattgccat cggctacacc atggtttacg gcattatcgg
    23581 catgatcaac ttcgcccacg gcgaggttta tatgatcggc agctatgtct catttatgat
    23641 catcgccgcg ctgatgatga tgggcattga taccggctgg ctgctggtgg cggcgggatt
    23701 cgtcggcgca atcgtcatcg ccagcgccta cggctggagt atcgaacggg tagcctatcg
    23761 cccggtgcgt aactctaagc gcctgattgc gctcatctcg gcaatcggca tgtccatctt
    23821 cctgcaaaac tacgttagcc tgactgaagg ttcgcgtgac gtggcgctgc ccagtctgtt
    23881 taacggtcag tgggtggtgg ggcatagcga aaacttctct gcctctatta ccaccatgca
    23941 ggcggtgatc tggattgtca ccttccttgc catgctggcg ctgacggttt tcattcgcta
    24001 ttcccgtatg gggcgcgcgt gtcgtgcctg cgcggaagac ctgaaaatgg cgagcctgct
    24061 tggcattaac accgaccggg tgattgcgct gacctttgtg attggcgcgg cgatggcggc
    24121 ggtggcgggt gtgctgctcg gtcagttcta cggcgtcatt aacccctaca tcggctttat
    24181 ggccgggatg aaagccttta ccgcggcggt gctcggtggg attggcagca ttccgggagc
    24241 gatgattggc ggcctgattc tggggattgc ggaggcgctc tcttctgcct atctgagtac
    24301 ggaatataaa gatgtggtct cattcgccct gctgattctg gtgctgctgg tgatgccgac
    24361 cggtattctg ggtcgcccgg aggtagagaa agtatgaaac cgatgcatat tgcaatggcg
    24421 ctgctctctg ccgcgatgtt ctttgtgctg gcgggcgtct ttatgggcgt gcaactggag
    24481 ctggatggca ccaaactggt ggtcgacacg gcttcggatg tccgttggca gtgggtgttt
    24541 atcggcacgg cggtggtctt tttcttccag cttttgcgac cggctttcca gaaagggttg
    24601 aaaagcgttt ccggaccgaa gtttattctg cccgccattg atggctccac ggtgaagcag
    24661 aaactgttcc tcgtggcgct gttggtgctt gcggtggcgt ggccgtttat ggtttcacgc
    24721 gggacggtgg atattgccac cctgaccatg atctacatta tcctcggtct cgggctgaac
    24781 gtggttgttg gtctttctgg tctgctggtg ctggggtacg gcggttttta cgccatcggc
    24841 gcttacactt ttgcgctgct caatcactat tacggcctgg gcttctggac ctgcctgccg
    24901 attgctggat taatggcagc ggcggcgggc ttcctgctcg gttttccggt gctgcgtttg
    24961 cgcggtgact atctggcgat cgttaccctc ggtttcggcg aaattgtgcg catattgctg
    25021 ctcaataaca ccgaaattac cggcggcccg aacggaatca gtcagatccc gaaaccgaca
    25081 ctcttcggac tcgagttcag ccgtaccgct cgtgaaggcg gctgggacac gttcagtaat
    25141 ttctttggcc tgaaatacga tccctccgat cgtgtcatct tcctctacct ggtggcgttg
    25201 ctgctggtgg tgctaagcct gtttgtcatt aaccgcctgc tgcggatgcc gctggggcgt
    25261 gcgtgggaag cgttgcgtga agatgaaatc gcctgccgtt cgctgggctt aagcccgcgt
    25321 cgtatcaagc tgactgcctt taccataagt gccgcgtttg ccggttttgc cggaacgctg
    25381 tttgcggcgc gtcagggctt tgtcagcccg gaatccttca cctttgccga atcggcgttt
    25441 gtgctggcga tagtggtgct cggcggtatg ggctcgcaat ttgcggtgat tctggcggca
    25501 attttgctgg tggtgtcgcg cgagttgatg cgtgatttca acgaatacag catgttaatg
    25561 ctcggtggtt tgatggtgct gatgatgatc tggcgtccgc agggcttgct gcccatgacg
    25621 cgcccgcaac tgaagctgaa aaacggcgca gcgaaaggag agcaggcatg agtcagccat
    25681 tattatctgt taacggcctg atgatgcgct tcggcggcct gctggcggtg aacaacgtca
    25741 atcttgaact gtacccgcag gagatcgtct cgttaatcgg ccctaacggt gccggaaaaa
    25801 ccacggtttt taactgtctg accggattct acaaacccac cggcggcacc attttactgc
    25861 gcgatcagca cctggaaggt ttaccggggc agcaaattgc ccgcatgggc gtggtgcgca
    25921 ccttccagca tgtgcgtctg ttccgtgaaa tgacggtaat tgaaaacctg ctggtggcgc
    25981 agcatcagca actgaaaacc gggctgttct ctggcctgtt gaaaacgcca tccttccgtc
    26041 gcgcccagag cgaagcgctc gaccgcgccg cgacctggct tgagcgcatt ggtttgctgg
    26101 aacacgccaa ccgtcaggcg agtaacctgg cctatggtga ccagcgccgt cttgagattg
    26161 cccgctgcat ggtgacgcag ccggagattt taatgctcga cgaacctgcg gcaggtctta
    26221 acccgaaaga gacgaaagag ctggatgagc tgattgccga actgcgcaat catcacaaca
    26281 ccactatctt gttgattgaa cacgatatga agctggtgat gggaatttcg gaccgaattt
    26341 acgtggtcaa tcaggggacg ccgctggcaa acggtacgcc ggagcagatc cgtaataacc
    26401 cggacgtgat ccgtgcctat ttaggtgagg cataagatgg aaaaagtcat gttgtccttt
    26461 gacaaagtca gcgcccacta cggcaaaatc caggcgctgc atgaggtgag cctgcatatc
    26521 aatcagggcg agattgtcac gctgattggc gcgaacgggg cggggaaaac caccttgctc
    26581 ggcacgttat gcggcgatcc gcgtgccacc agcgggcgaa ttgtgtttga tgataaagac
    26641 attaccgact ggcagacagc gaaaatcatg cgcgaagcgg tggcgattgt cccggaaggg
    26701 cgtcgcgtct tctcgcggat gacggtggaa gagaacctgg cgatgggcgg tttttttgct
    26761 gaacgcgacc agttccagga gcgcataaag tgggtgtatg agctgtttcc acgtctgcat
    26821 gagcgccgta ttcagcgggc gggcaccatg tccggcggtg aacagcagat gctggcgatt
    26881 ggtcgtgcgc tgatgagcaa cccgcgtttg ctactgcttg atgagccatc gctcggtctt
    26941 gcgccgatta tcatccagca aattttcgac accatcgagc agctgcgcga gcaggggatg
    27001 actatctttc tcgtcgagca gaacgccaac caggcgctaa agctggcgga tcgcggctac
    27061 gtgctggaaa acggccatgt agtgctttcc gatactggtg atgcgctgct ggcgaatgaa
    27121 gcggtgagaa gtgcgtattt aggcgggtaa taacacgttg attgataggg agtcaaaaga
    27181 ctcctttgag acaggtgaca aatgtaaaat tgcctgatgc gctgcgctta tcaggcctac
    27241 tgggtgagtg gcaatatgtt gaatttgcac gatcttgtag gcctgataag gcgtttacgc
    27301 cgcatccggc atgaaacgat gagcaatctg tagagtttga ttcagacctt ctatattttc
    27361 ccgcttatcc gtgccccatc tcccattttc cctcacccac gccgtcaccg ccttgtcatc
    27421 tttctgacac cttactatct tacaaatgta acaaaaaagt tatttttctg taattcgagc
    27481 atgtcatgtt accccgcgag cataaaacgc gtgaattcgc gcattcggta caacaagaga
    27541 gataaacgat gaaaccgtta cattatacag cttcagcact ggcgctcgga ctggcgttaa
    27601 tggggaatgc acaggcagtg acgaccattc cgttctggca ttctatggaa ggggaactgg
    27661 gtaaagaggt ggattctctg gcccaacgtt ttaacgccga aaacccggat tacaaaattg
    27721 taccgaccta taaaggcaac tacgaacaga atttaagcgc ggggattgcc gcatttcgta
    27781 ccggcaacgc gccggctatt ttgcaggttt atgaagttgg caccgccacc atgatggcgt
    27841 cgaaagccat taaaccggtg tatgacgtgt ttaaagaggc agggattcag ttcgatgagt
    27901 cgcagtttgt gccgacggtt tcaggttact actccgacag caaaacgggc cacttactct
    27961 cccagccatt caacagctcg acccccgttc tctattacaa caaagacgcc ttcaagaaag
    28021 caggattaga cccggaacag ccgccgaaaa cctggcagga tctggcggac tatgccgcga
    28081 aactgaaagc ctccggcatg aagtgcggct acgccagcgg ctggcagggc tggatccaac
    28141 tggaaaactt tagcgcctgg aacggtctgc cgtttgccag caaaaacaac ggctttgacg
    28201 gcacggacgc ggtgctggag ttcaacaagc cggagcaggt gaaacacatc gccatgctcg
    28261 aggagatgaa caagaagggc gacttcagct acgtcggtcg taaggatgaa tccaccgaga
    28321 agttctataa cggtgattgc gcgatgacca ccgcctcttc cggttctctt gccaacattc
    28381 gcgagtacgc caaatttaac tacggcgtag gcatgatgcc ttacgacgcc gatgcgaaag
    28441 atgcgccaca aaacgccatt atcggcggag ccagcctgtg ggtgatgcag ggtaaagata
    28501 aagaaacgta taccggtgtg gcgaagttcc tcgatttcct cgcgaagcca gaaaacgctg
    28561 ccgagtggca tcagaaaacc ggttatctgc caatcaccaa agcagcgtat gacctgaccc
    28621 gtgagcaggg cttttatgag aaaaacccag gggcggatac cgcgacgcgt cagatgctga
    28681 ataagccgcc gttgccgttc accaaagggc tgcgtctggg caacatgccg cagatccgcg
    28741 tgattgtgga tgaagagctg gagagcgtgt ggaccggtaa gaagacacca cagcaggcac
    28801 tggataccgc cgttgagcgt ggaaatcagt tgctgcgccg ctttgagaaa tcgacgaagt
    28861 cttaatcagt gtaatgtcgg atgcgtttcg cttatctgac ctggcatcgc gtgtaggccg
    28921 gataagcgaa gcgcatccgg cacagttcag gaattaaccg taatgtcatc atcccgtccg
    28981 gtgttccgct cgcgctggct gccttatctg ctggtcgcgc cgcagctcat catcaccgtt
    29041 atctttttta tctggcctgc gggcgaagcg ttgtggtact cgctacaaag cgtcgatccg
    29101 tttggtttct ccagccagtt tgtcggcctg gataacttcg tcacgctgtt ccatgacagc
    29161 tactatctcg actccttctg gacgacgata aaattcagca cctttgtcac cgtcagcggt
    29221 ttgctggtat cgctgttctt tgcggcgctg gtggagtaca tcgtgcgcgg cagccgtttc
    29281 tatcaaacct taatgttgct gccttacgcc gtggctcccg ccgttgccgc cgtattgtgg
    29341 atcttcctgt ttaaccccgg tcgcgggctg atcacccatt ttctcgcgga gttcggctac
    29401 gactggaacc acgcgcaaaa cagcggtcag gcaatgtttc tggtggtgtt tgcctcagta
    29461 tggaagcaaa tcagctacaa cttcctgttc ttctatgccg cgctgcaatc cattccccgt
    29521 tcgttgatcg aagccgcagc catcgacggt gcagggccga ttcgccgctt ctttaagatt
    29581 gcgctgccgc ttatcgcccc ggtgagtttc ttcctgctgg tagtgaacct ggtgtatgcc
    29641 ttcttcgaca ccttcccggt gatcgacgcc gccacgtccg gcgggccggt tcaggccacc
    29701 acgacgctga tttataagat ctaccgcgaa ggttttaccg gactggatct ggcttcgtct
    29761 gccgcacagt cggtggtgtt gatgttcctc gtcatcgtgc tgacggtggt gcagttccgc
    29821 tatgttgaaa gcaaggtgcg ttaccaatga ttgagaaccg tccgtggctg acgatattca
    29881 gccataccat gctgatcctc gggatcgcgg tgatcctctt cccgctgtac gtggcgtttg
    29941 tcgcggcgac gctggataaa caggccgtct atgccgcgcc gatgacgctc atccccggca
    30001 cacatctgct ggaaaacatc cacaacatct gggtgaacgg ggtaggcacg aatagcgcgc
    30061 cgttctggcg gatgttgctt aacagctttg tgatggcgtt cagcattacg ctcggcaaaa
    30121 ttaccgtctc gatgctctcg gcatttgcca ttgtctggtt tcgttttccg ctacgtaacc
    30181 tcttcttctg gatgattttt atcaccctga tgctgccggt tgaagtacgt atcttcccga
    30241 cggtggaagt catcgccaac ctgcagatgc tcgacagcta cgccggttta acgctgccgc
    30301 tgatggcctc ggcgaccgct actttcctat tccgccagtt ctttatgacg ctgccggatg
    30361 agctggtgga agccgcgcgg atcgacggcg catcgccaat gcgcttcttt tgcgacatcg
    30421 tttttccgct ctccaaaact aatctggcgg cgctgtttgt gatcaccttt atctacggct
    30481 ggaatcagta tttgtggccg ttgttgatta ttaccgatgt ggatctcggc accaccgtgg
    30541 cagggatcaa agggatgatc gctacaggcg aaggcaccac ggaatggaac tcagtgatgg
    30601 cggcgatgtt gttaacgctt atccctccgg tggtgattgt tttagtgatg cagcgtgcct
    30661 tcgtgcgcgg cctggtcgat agtgagaaat aagatggcag gactgaaatt acaggcagta
    30721 accaaaagct gggatggtaa aacccaggtc attaaaccgc tgacccttga tgtggcggat
    30781 ggcgaattta tcgtgatggt cgggccgtct ggctgcggga aatcgacgct gctgcgcatg
    30841 gttgccgggc tggagcgggt gacagaaggc gatatctgga tcaacgacca gcgcgtgact
    30901 gaaatggagc caaaagatcg cgggattgcg atggtgttcc agaactacgc gctttatccg
    30961 catatgagtg tcgaagaaaa catggcgtgg gggctgaaaa ttcgcggcat gggcaagcag
    31021 caaatagccg agcgcgttaa agaagcggcg cgcattctgg agctggacgg tctgctcaaa
    31081 cgtcgcccgc gcgagctttc cggcggtcag cgtcagcgtg tagcgatggg ccgcgcgatt
    31141 gtgcgcgatc cggcggtgtt cctgtttgat gagccgctct ctaacctcga tgccaagctg
    31201 cgcgtgcaga tgcgccttga gctgcaacag ctgcaccgtc gcctgaaaac gacttcactc
    31261 tacgttactc acgatcaggt tgaggcgatg accctcgccc agcgagtaat ggtgatgaac
    31321 ggcggcgttg ccgaacagat tggcacaccg gttgaagtct acgaaaagcc cgccagcctg
    31381 tttgtggcga gttttatcgg cagtccggcg atgaacctgc tgacaggccg cgtgaataac
    31441 gaaggcacgc atttcgaact ggacggcggt attgtgctgc cgctaaacgg tggctaccgt
    31501 cagtatgccg ggcgtaaaat gaccctcggc attcgcccgg aacatattgc gctaagctcg
    31561 caagcagaag gtggcgtacc gctggtgatg gatacgctgg agatcctcgg cgcagataac
    31621 ctggcgcacg gacgctggag cgagcagaag ctggtggtgc gactggcgca tcaggagcgc
    31681 ccgacggcag gcagcacgct gtggctgcat ctgccggaaa atcagctaca tctttttgat
    31741 ggtgaaacag gacaacgagt atgaataact ggccttatcc ccgcatcgtc gcacatcgtg
    31801 gcggcggtaa gctggccccg gaaaacaccc tggcggcaat cgacgtcggg gcaaaatacg
    31861 gtcataagat gatcgaattt gacgcgaagt tatcgaaaga tggcgagatc ttcctgctcc
    31921 atgacgacaa tctcgaacgc accagcaacg gctggggcgt cgcgggtgaa ctgaactggc
    31981 aggatttact gcgcgtggat gcgggcagtt ggtacagcaa agcgtttaaa ggtgagccgc
    32041 tgccgttgct ttcgcaggtg gcggaacgct gtcgcgaaca cgggatgatg gcgaatatcg
    32101 aaatcaaacc caccactggc actggaccat taacgggcaa aatggtggcg ctggcggcac
    32161 gccaactgtg ggccggtatg acgccgccgc tgctgtcatc gtttgagatt gatgctttag
    32221 aagctgcaca gctggcggca ccggaactgc cgcgtggttt attgcttgat gagtggcgcg
    32281 acgactggcg cgaactgacc gcgcggctgg gctgcgtctc tattcatctc aatcataagt
    32341 tactcgataa agtgcgagtg atgcagttga aagacgccgg actgcggatt ctggtttata
    32401 ccgtcaataa accccagcgc gcggcagagt tgctgcgctg gggcgtggat tgcatctgta
    32461 ccgatgcgat tgacgtgatt ggtccgaact ttacggccca atagttttca acggaatgtc
    32521 aggctgcggc gtgctgggct gattcagcat gtcgccgttt ctcctctccg gcagcatatg
    32581 ctgctgattc aacgaactat ccggattacg gttgctgttt aacatcccgc cgttggtgtt
    32641 gggcagcatt tgctgccggg cgggatttcg ctcccccggc tgtgactgca acacccgctg
    32701 agaattattg tttatctggt tttctaaatg ctgctgttgc aactgagttt gcgttttcag
    32761 ttgctgattc agcatccctt tttgctggat ttgctgagtc tgcatctggg tttgcatccg
    32821 ctgctggctg ggtatctgat accccggctg gttagggttg ttcagagtat taatgggctg
    32881 tgcaaagccg acaaacggca ggagtgccgt aagaatcaga agtcgtttca tcgcgtatcc
    32941 tcctctgaag atatccttta agtttactcg cttcccgaca aaacgatgat taattcagag
    33001 ttatatacca ggcttagctg gggttgcccc ttaatctctg gagaataacg atgataaaac
    33061 cgacgttttt acgccgggtg gccattgctg ctctgctctc aggaagttgt tttagcgccg
    33121 ccgccgcgcc tcctgcgccg cccgtctcgt atggtgtgga ggaagatgtc ttccacccgg
    33181 tacgcgcgaa acagggaatg gtagcgtctg tggacgccac tgccactcag gtgggggtgg
    33241 atattctcaa ggagggcggg aatgccgttg atgccgccgt ggcggtgggc tacgcgctgg
    33301 cggtaacgca tccgcaggca gggaatctgg gcggtggtgg ttttatgtta atccgctcga
    33361 aaaatggcaa taccacggct atcgatttcc gcgaaatggc acccgccaaa gcgacccgcg
    33421 atatgttcct cgatgatcag ggcaacccgg acagcaaaaa atcactcact tcgcatctgg
    33481 cttccggcac accgggtacg gtagcaggtt tctcgctggc gctggataaa tacggcacca
    33541 tgccgctgaa caaagtcgtg cagcccgcgt ttaaactggc acgcgatggt tttatcgtta
    33601 acgacgcgct ggctgacgat ctcaaaacct acggtagcga agtgttgccg aatcacgaaa
    33661 acagtaaagc tatcttctgg aaagagggcg agccgctgaa aaagggcgac acgctggtgc
    33721 aggcgaacct ggcaaagagc ttggagatga ttgctgaaaa cggcccggac gaattctata
    33781 aaggcacgat tgcggaacag atcgcccagg agatgcagaa aaacggtggc ttgatcacta
    33841 aagaagattt agcagcctat aaagcggtcg aacgcactcc gataagcggc gattatcgcg
    33901 ggtatcaggt ttactccatg ccaccgccat cctccggcgg gatccatatc gtacaaatcc
    33961 tcaatattct ggaaaacttc gatatgaaga aatacggctt tggcagcgcc gatgcgatgc
    34021 aaatcatggc agaagcggag aaatacgcct acgccgaccg ctcggaatat cttggcgacc
    34081 cggattttgt caaagtaccg tggcaggcgc tgaccaataa agcctatgcc aaatctattg
    34141 ccgatcaaat tgatatcaat aaagcgaagc catccagcga aattcgcccc ggcaagcttg
    34201 cgccttatga gagtaatcaa actacccatt actcagtggt ggataaagat ggtaacgcgg
    34261 tggcggtgac ctatacgctg aacaccacct tcggtacggg cattgtcgcg ggcgagagcg
    34321 gtattctgct taataaccag atggatgatt tctccgccaa accgggcgta ccgaacgttt
    34381 acgggctggt gggcggtgat gccaacgccg tcgggccgaa caaacgcccg ctgtcgtcga
    34441 tgtcgccgac cattgtggtg aaagacggta aaacctggct ggttaccggt agcccaggcg
    34501 gtagccggat catcactaca gtgctgcaaa tggtggtgaa tagcatcgat tatggcttga
    34561 acgtcgccga agcgaccaat gcgccgcgtt tccaccatca gtggttgccg gacgagctgc
    34621 gtgtcgaaaa agggtttagc ccggatacgc tcaagctgct ggaagcaaaa ggtcagaaag
    34681 tggcgctgaa agaggcgatg ggcagtacac aaagcattat ggttgggccg gacggtgagt
    34741 tgtacggcgc atccgacccg cgctcggtgg atgatttaac ggcggggtac taaggttagc
    34801 ggccctcttc gtgggaagag ggctattttg tcagggcaag ccgaaggtag ccttttttat
    34861 ttcgtaatcc tgtagatatt cttccagcgg ttttgccgtt cccagagaat gaatttcacc
    34921 actgtcttta tcaataataa aaggtgcgtt accagctaag cgcgcggcct catctccagt
    34981 ttcgagaaat tctcgtgctt cgaaacagaa ataccagccc tggctaaagc gtccatgtag
    35041 agtaatgacg accgggagat ctgcatcatc aaggtaatgg ttcgctttcg cgaatgcgtc
    35101 gtgataagta atcataatta taataaatat tattgttgag tgttatatta ttattcctgt
    35161 gtgatacatt gagcaaagac gcgttcatct tcgtcaaaga tattattaaa tgctggtttt
    35221 gaaaaaagtt catcggataa gatatagtca cgaaataagt atctgctaat attttatgat
    35281 ttctttttca gaacgtcgaa cgggattttc ttatttaaga tatcagaatc ttatgattcg
    35341 ggtaaaattc taaataaatc aacatgtcat taaaatcatc atagccatta gctatttcgg
    35401 ctaaaataga gactacatgt cttcggtcca tctcacttaa ggagtgtagt tccgttgtaa
    35461 gtttttccat agcttgcact gctaaatttc gaacaaggaa ttttctgctg gtaatctcta
    35521 aaaagatggc atggtttaca atgatttttg tttccttttg attattatga acaactgtcc
    35581 atgatttcgt ttaagaatga agagaaatca ctaaacgaac tgaatatatt ttctgtgcca
    35641 atattatctc taatttcaaa aaagttactt ttaatgtcat aagtaaatat tgaaatgcta
    35701 taatccccga tcactaaccg ttcttgtaga tcagggttta tgaaatcatc attatttcta
    35761 taaaattcat ttacggcaaa aaggttttta actgaaggtt ctggaatcga gaggctaaat
    35821 aatcgtaatc cattaacttc gaatccatcc attgctctta aaaaagtaag ataatcaggt
    35881 tgattcttaa aaagaatact aacttcatta cataacttct ccaggcaatt agttgaatta
    35941 gaattaaatt ctatttggat tatactttca ataaatgatt ccttgagcgg tgc
//
LOCUS       DAPOAV010000043        35911 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.043, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000043 DAPOAV010000000
VERSION     DAPOAV010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 35911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35911
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.043"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(143..979)
                     /gene="bglG"
                     /locus_tag="RN951_002397"
     CDS             complement(143..979)
                     /gene="bglG"
                     /locus_tag="RN951_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional antiterminator BglG"
                     /protein_id="HDX2527387.1"
                     /translation="MNMQITKILNNNVVVVIDDQQREKVVMGRGIGFQKRAGERINSS
                     GIEKEYALSSHELNGRLSELLSHIPLEVMATCDRIISLAQERLGKLQDSIYISLTDHC
                     QFAIKRFQQNVLLPNPLLWDIQRLYPKEFQLGEEALTIIDKRLGVQLPKDEVGFIAMH
                     LVSAQMSGNMEDVAGVTQLMREMLQLIKFQFSLNYQEESLSYQRLVTHLKFLSWRILE
                     HASINDSDESLQQAVKQNYPQAWQCAERIAIFIGLQYQRKISPAEIMFLAINIERVRK
                     EH"
     gene            complement(1265..1990)
                     /gene="phoU"
                     /locus_tag="RN951_002398"
     CDS             complement(1265..1990)
                     /gene="phoU"
                     /locus_tag="RN951_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDX2527388.1"
                     /translation="MDSLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMH
                     NQDSDLAKRVIEGDKNVNMMEVAIDEACVRIIAKRQPTASDLRLVMVISKTIAELERI
                     GDVADKICRTALEKFSQQHQPLLVSLESLGRHTIQMLHDVLDAFARMDIDEAVRIYRE
                     DKKVDQEYEGIVRQLMTYMMEDSRTIPSVLTALFCARSIERIGDRCQNICEFIFYYVK
                     GQDFRHVGGDELDKLLAGKDSDK"
     gene            complement(2005..2778)
                     /gene="pstB"
                     /locus_tag="RN951_002399"
     CDS             complement(2005..2778)
                     /gene="pstB"
                     /locus_tag="RN951_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HDX2527389.1"
                     /translation="MSMVETAPSKIQVRNLNFYYGKFHALKNINLDIAKNQVTAFIGP
                     SGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNILTNSQDIALLRAKVGMVFQKPTP
                     FPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQ
                     RLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKQDYTVVIVTHNMQQAARC
                     SDHTAFMYLGELIEFSNTDDLFTKPAKKQTEDYITGRYG"
     gene            complement(2961..3851)
                     /gene="pstA"
                     /locus_tag="RN951_002400"
     CDS             complement(2961..3851)
                     /gene="pstA"
                     /locus_tag="RN951_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDX2527390.1"
                     /translation="MAMVEMQTTAALAESRRKMQARRRLKNRIALTLSMATMAFGLFW
                     LIWILMSTITRGIDGMSLALFTEMTPPPNTEGGGLANALAGSGLLILWATVFGTPLGI
                     MAGIYLAEYGRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEHFSGWAGVIAL
                     ALLQVPIVIRTTENMLKLVPYSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAI
                     ARIAGETAPLLFTALSNQFWSTDMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLIIT
                     LCVLLLNILARVVFAKNKHG"
     gene            complement(3851..4810)
                     /gene="pstC"
                     /locus_tag="RN951_002401"
     CDS             complement(3851..4810)
                     /gene="pstC"
                     /locus_tag="RN951_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008806729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstC"
                     /protein_id="HDX2527391.1"
                     /translation="MAATKPAFNPPGKKGDIIFSVLVKLAALIVLLMLGGIIVSLIIS
                     SWPSIQKFGLAFLWTKEWDAPNDIYGALVPIYGTLVTSFIALLIAVPVSFGIALFLTE
                     LAPGWLKRPLGIAIELLAAIPSIVYGMWGLFIFAPLFAVYFQEPVGNIMSNIPIVGAL
                     FSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRI
                     VLPFTKNGVIGGIMLGLGRALGETMAVTFIIGNTYQLDSASLYMPGNSITSALANEFA
                     EAESGLHVAALMELGLILFVITFIVLAASKFMIMRLAKNEGAR"
     gene            complement(4897..5937)
                     /gene="pstS"
                     /locus_tag="RN951_002402"
     CDS             complement(4897..5937)
                     /gene="pstS"
                     /locus_tag="RN951_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HDX2527392.1"
                     /translation="MKVMRTTVATVVAATLSMSAFSVFAEASLTGAGATFPAPVYAKW
                     ADTYQKETGNKVNYQGIGSSGGVKQIIANTVDFGASDAPLSDEKLAQEGLFQFPTVIG
                     GVVLAVNIPGLKSGELVLDGKTLGDIYLGKIKKWDDEAIAKLNPGLKLPSQNIAVVRR
                     ADGSGTSFVFTSYLAKVNEEWKNNVGTGSTVKWPIGLGGKGNDGIAAFVQRLPGAIGY
                     VEYAYAKQNNLAYTKLISADGKPVSPTEENFANAAKGADWSKTFAQDLTNQKGEDAWP
                     ITSTTFILIHKDQKKPEQGTEVLKFFDWAYKTGAKQANDLDYASLPDSVVEQVRAAWK
                     TNIKDSSGKPLY"
     gene            complement(6251..8080)
                     /gene="glmS"
                     /locus_tag="RN951_002403"
     CDS             complement(6251..8080)
                     /gene="glmS"
                     /locus_tag="RN951_002403"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HDX2527393.1"
                     /translation="MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMT
                     RLRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGEPSEVNAHPHVSEHIVVVHNGII
                     ENHEPLREELKARGYTFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTV
                     IMDSRHPDTLLAARSGSPLVIGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRR
                     SVNIFDKTGAEVKRQDIESNLQYDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQ
                     VDLSELGPNADELLSKVEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYR
                     KSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMT
                     NAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLS
                     QDKRIEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPL
                     ALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMP
                     HVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSVTVE"
     gene            complement(8242..9612)
                     /gene="glmU"
                     /locus_tag="RN951_002404"
     CDS             complement(8242..9612)
                     /gene="glmU"
                     /locus_tag="RN951_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HDX2527394.1"
                     /translation="MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAAN
                     ELGAAHVHLVYGHGGDLLKQALKDDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILML
                     YGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATD
                     EQRQIQEINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQ
                     RLSEVEGVNNRLQLSRLERVYQSEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDT
                     NVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIGPFARLRP
                     GAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANK
                     FKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWR
                     RPVKKK"
     gene            complement(9964..10383)
                     /gene="atpC"
                     /locus_tag="RN951_002405"
     CDS             complement(9964..10383)
                     /gene="atpC"
                     /locus_tag="RN951_002405"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001251972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HDX2527395.1"
                     /translation="MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLT
                     AIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKA
                     EEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM"
     gene            complement(10404..11786)
                     /gene="atpD"
                     /locus_tag="RN951_002406"
     CDS             complement(10404..11786)
                     /gene="atpD"
                     /locus_tag="RN951_002406"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017800291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HDX2527396.1"
                     /translation="MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQ
                     QQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEI
                     GEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNM
                     MELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRL
                     RVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEM
                     GVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPA
                     VDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVA
                     RARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSI
                     EEAVEKAKKL"
     gene            complement(11813..12676)
                     /gene="atpG"
                     /locus_tag="RN951_002407"
     CDS             complement(11813..12676)
                     /gene="atpG"
                     /locus_tag="RN951_002407"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HDX2527397.1"
                     /translation="MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRP
                     YAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAE
                     MKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAY
                     DEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDT
                     LLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQE
                     LTEIVSGAAAV"
     gene            complement(12727..14268)
                     /gene="atpA"
                     /locus_tag="RN951_002408"
     CDS             complement(12727..14268)
                     /gene="atpA"
                     /locus_tag="RN951_002408"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HDX2527398.1"
                     /translation="MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGL
                     ADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRG
                     LLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIG
                     RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGAL
                     ANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLL
                     LRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQA
                     GDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGG
                     IRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFA
                     AERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFK
                     ATQSW"
     gene            complement(14281..14814)
                     /gene="atpH"
                     /locus_tag="RN951_002409"
     CDS             complement(14281..14814)
                     /gene="atpH"
                     /locus_tag="RN951_002409"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HDX2527399.1"
                     /translation="MSEFITVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQM
                     AELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENGRLNALPDVLEQFIHLRAV
                     SEATAEVDVISAAALSEQQLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVI
                     DGSVRGRLERLADVLQS"
     gene            complement(14829..15299)
                     /gene="atpF"
                     /locus_tag="RN951_002410"
     CDS             complement(14829..15299)
                     /gene="atpF"
                     /locus_tag="RN951_002410"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HDX2527400.1"
                     /translation="MNLNATILGQAIAFVLFVLFCMKYVWPPLMAAIEKRQKEIADGL
                     ASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQANKRRSQILDEAKAEAEQERTKIV
                     AQAQAEIEAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL"
     gene            complement(15361..15600)
                     /gene="atpE"
                     /locus_tag="RN951_002411"
     CDS             complement(15361..15600)
                     /gene="atpE"
                     /locus_tag="RN951_002411"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HDX2527401.1"
                     /translation="MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPD
                     LIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA"
     gene            complement(15647..16462)
                     /gene="atpB"
                     /locus_tag="RN951_002412"
     CDS             complement(15647..16462)
                     /gene="atpB"
                     /locus_tag="RN951_002412"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HDX2527402.1"
                     /translation="MASENMTPQDYIGHHLNNLQLDLRTFSLVDPQNPPATFWTINID
                     SMFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIA
                     PLALTIFVWVFLMNLMDLLPIDLLPYIAEHVLGLPALRVVPSADVNVTLSMALGVFIL
                     ILFYSIKMKGIGGFTKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAG
                     ELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH"
     gene            complement(16471..16851)
                     /gene="atpI"
                     /locus_tag="RN951_002413"
     CDS             complement(16471..16851)
                     /gene="atpI"
                     /locus_tag="RN951_002413"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418195.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit I"
                     /protein_id="HDX2527403.1"
                     /translation="MSVSLVSRNVARKLLLVQLLVVIASGLLFSLKDPFWGVSAISGG
                     LAVFLPNVLFMIFAWRHQAHTPAKGRVAWTFAFGEAFKVLAMLVLLVVALAVLKAVFL
                     PLIVTWVLVLVVQILAPAVINNKG"
     gene            complement(17468..18091)
                     /gene="rsmG"
                     /locus_tag="RN951_002414"
     CDS             complement(17468..18091)
                     /gene="rsmG"
                     /locus_tag="RN951_002414"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HDX2527404.1"
                     /translation="MLNKLSLLLKDAGISLTDHQKNQLIAYVNMLHKWNKAYNLTSVR
                     DPNEMLVRHILDSIVVAPYLQGERFIDVGTGPGLPGIPLSIVRPEAHFTLLDSLGKRV
                     RFLRQVQHELKLENIEPVQSRVEEFPSEPPFDGVISRAFASLNDMVSWCHHLPGEQGR
                     FYALKGQMPEDEIALLPEEYQVESVVKLQVPALDGERHLVVIKANKI"
     gene            complement(18155..20044)
                     /gene="mnmG"
                     /locus_tag="RN951_002415"
     CDS             complement(18155..20044)
                     /gene="mnmG"
                     /locus_tag="RN951_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HDX2527405.1"
                     /translation="MFYPDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQ
                     MSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRV
                     LYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLD
                     GKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQ
                     HGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRSNLDRSPMYAGVIEGVGPRY
                     CPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENA
                     KIVRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAA
                     RLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTE
                     IGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAEAAAEVNAHLTAPLSREAS
                     GEDLLRRPEMTYEKLTTLTPFAPSLTDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNE
                     NTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGM
                     LRRSA"
     gene            complement(20423..20866)
                     /gene="mioC"
                     /locus_tag="RN951_002416"
     CDS             complement(20423..20866)
                     /gene="mioC"
                     /locus_tag="RN951_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein MioC"
                     /protein_id="HDX2527406.1"
                     /translation="MADITLISGSTLGGAEYVAEHLAEKLEEAGFTTETLHGPLLEDL
                     PASGIWLVISSTHGAGDIPDNLSPFYEALQEQKPDLSAVRFGAIGIGSREYDTFCGAI
                     DKLEAELKNSGAKQTGETLKINILDHDIPEDPAEEWLGSWVNLLK"
     gene            complement(20956..21414)
                     /gene="asnC"
                     /locus_tag="RN951_002417"
     CDS             complement(20956..21414)
                     /gene="asnC"
                     /locus_tag="RN951_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator AsnC"
                     /protein_id="HDX2527407.1"
                     /translation="MENYLIDNLDRGILEALMGNARTAYAELAKQFGVSPGTIHVRVE
                     KMKQAGIITGARIDVSPKQLGYDVGCFIGIILKSAKDYPSALAKLESLDEVTEAYYTT
                     GHYSIFIKVMCRSIDALQHVLINKIQTIDEIQSTETLIVLQNPIMRTIKP"
     gene            21566..22558
                     /gene="asnA"
                     /locus_tag="RN951_002418"
     CDS             21566..22558
                     /gene="asnA"
                     /locus_tag="RN951_002418"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HDX2527408.1"
                     /translation="MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGT
                     QDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPD
                     EDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPF
                     LPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDY
                     DDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLEL
                     EWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAAVRESVPSLL"
     gene            complement(22563..24014)
                     /gene="viaA"
                     /locus_tag="RN951_002419"
     CDS             complement(22563..24014)
                     /gene="viaA"
                     /locus_tag="RN951_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA stimulator ViaA"
                     /protein_id="HDX2527409.1"
                     /translation="MLTLDTLNVMLAVSEEGLIEEMIIALLASPQLAVFFEKFPRLKA
                     AITDDVPRWREALRSRLKDARVPPELTEEVMCYQQSQLLSTPQFIVQLPQILDLLHRL
                     NSPWAEQARQLVDANSTITSALHTLFLQRWRLSLIVQATTLNQQLLEEEREQLLSEVQ
                     ERMTLSGQLEPILADNNTAAGRLWDMSAGQLKRGDYQLIVKYGEFLNEQPELKRLAEQ
                     LGRSREAKSIPRNDAQMETFRTMVREPATVPEQVDGLQQSDDILRLLPPELATLGITE
                     LEYEFYRRLVEKQLLTYRLHGESWREKVIERPVVHKDYDEQPRGPFIVCVDTSGSMGG
                     FNEQCAKAFCLALMRIALAENRRCYIMLFSTEIVRYELSGPQGIEQAIRFLSQQFRGG
                     TDLASCFRAIMERLQSREWFDADAVVISDFIAQRLPDDVTSKVKELQRVHQHRFHAVA
                     MSAHGKPGIMRIFDHIWRFDTGMRSRLLRRWRR"
     gene            complement(24008..25504)
                     /gene="ravA"
                     /locus_tag="RN951_002420"
     CDS             complement(24008..25504)
                     /gene="ravA"
                     /locus_tag="RN951_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418202.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA"
                     /protein_id="HDX2527410.1"
                     /translation="MAHPHLLAERISRLSSSLEKGLYERSHAIRLCLLAALSGESVFL
                     LGPPGIAKSLIARRLKFAFQNARAFEYLMTRFSTPEEVFGPLSIQALKDEGRYERLTS
                     GYLPEAEIVFLDEIWKAGPAILNTLLTAINERQFRNGAHVEKIPMRLLVAASNELPEA
                     DSSLEALYDRMLIRLWLDKVQDKANFRSMLTSQQDENDNPVPDALQVTDEEYERWQKE
                     IGEITLPDHVFELIFMLRQQLDKLPDAPYVSDRRWKKAIRLLQASAFFSGRSAVTPVD
                     LILLKDCLWYDAQSLNLIQQQIDVLMTGHAWQQQGMLTRLGAIVQRHLQLQQQQSDKT
                     ALTVIRLGGIFSRRQQYQLPVNVTASTLTLLLQKPLKLHDMEVVHISFERSALEQWLS
                     KGGEIRGKLNGIGFAQKLNLEVDSAQHLVVRDVSLQGSTLALPGSSAEGLPGEIKQQL
                     EELESDWRKQHALFSEQQKCLFIPGDWLGRIEASLQDVGAQIRQAQQC"
     gene            25727..27595
                     /gene="kup"
                     /locus_tag="RN951_002421"
     CDS             25727..27595
                     /gene="kup"
                     /locus_tag="RN951_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity potassium transporter Kup"
                     /protein_id="HDX2527411.1"
                     /translation="MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGV
                     ERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSML
                     VIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVSLSIIVLTLLFMIQKH
                     GTAMVGKLFAPIMLTWFLILAGLGLRSIIANPEVLHALNPMWAVHFFLEYKTVSFIAL
                     GAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNP
                     FFLLAPDWALIPLLIIAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMES
                     GQIYIPFVNWMLYVAVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHW
                     NKYFVALILIAFLCVDIPLFTANLDKLLSGGWLPLSLGTVMFIVMTTWKSERFRLLRR
                     MHEHGNSLEAMIASLEKSPPARVPGTAVYMSRAINVIPFALMHNLKHNKVLHERVILL
                     TLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMME
                     TSFFMSHESLILGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI"
     gene            27762..28181
                     /gene="rbsD"
                     /locus_tag="RN951_002422"
     CDS             27762..28181
                     /gene="rbsD"
                     /locus_tag="RN951_002422"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HDX2527412.1"
                     /translation="MKKGTVLNSDISSVISRLGHTDTLVVCDAGLPIPKSTTRIDMAL
                     TQGVPSFMQVLGVVTNEMQVEAAIIAEEIKHHNPQLHETLLTHLEQLQKHQGNTIEIR
                     YTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF"
     gene            28189..29694
                     /gene="rbsA"
                     /locus_tag="RN951_002423"
     CDS             28189..29694
                     /gene="rbsA"
                     /locus_tag="RN951_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter ATP-binding protein RbsA"
                     /protein_id="HDX2527413.1"
                     /translation="MEALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKS
                     TMMKVLTGIYTRDAGTLLWLGKETTFTGPKSSQEAGIGIIHQELNLIPQLTIAENIFL
                     GREFVNRFGKIDWKTMYAEADKLLAKLNLRFKSDKLVGDLSIGDQQMVEIAKVLSFES
                     KVIIMDEPTDALTDTETESLFRVIRELKSQGRGIVYISHRMKEIFEICDDVTVFRDGQ
                     FIAEREVASLTEDSLIEMMVGRKLEDQYPHLDKAPGDIRLKVDNLCGPGVNDVSFTLR
                     KGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDGLANGIVYISE
                     DRKRDGLVLGMSVKENMSLTALRYFSRAGGSLKHADEQQAVSDFIRLFNVKTPSMEQA
                     IGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKADGLSIIL
                     VSSEMPEVLGMSDRIIVMHEGHLSGEFTREQATQEVLMAAAVGKLNRVNQE"
     gene            29699..30664
                     /gene="rbsC"
                     /locus_tag="RN951_002424"
     CDS             29699..30664
                     /gene="rbsC"
                     /locus_tag="RN951_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002882531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HDX2527414.1"
                     /translation="MTTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTIN
                     NLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAASIVGIEVNALVAVA
                     AALALGAAIGAVTGVIVAKGRVQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADL
                     FGWFGIGRPLGVPTPVWIMGIVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNK
                     IKIIVYSLCGLLASLAGIIEVARLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIV
                     GTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKKQ"
     gene            30689..31579
                     /gene="rbsB"
                     /locus_tag="RN951_002425"
     CDS             30689..31579
                     /gene="rbsB"
                     /locus_tag="RN951_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter substrate-binding protein
                     RbsB"
                     /protein_id="HDX2527415.1"
                     /translation="MNMKKLATLVSAVALSATVSANAMAKDTIALVVSTLNNPFFVSL
                     KDGAQKEADKLGYNLVVLDSQNNPAKELANVQDLTVRGTKILLINPTDSDAVGNAVKM
                     ANQANIPVITLDRQATKGEVVSHIASDNVLGGKIAGDYIAKKAGEGAKVIELQGIAGT
                     SAARERGEGFQQAVAAHKFNVLASQPADFDRTKGLNVMQNLLTAHPDVQAIFAQNDEM
                     ALGALRALQTAGKSDVMVVGFDGTPDGEKAVNDGKLAATIAQLPDQIGAKGVETADKV
                     LKGEKVQAKYPVDLKLVVKQ"
     gene            31705..32634
                     /gene="rbsK"
                     /locus_tag="RN951_002426"
     CDS             31705..32634
                     /gene="rbsK"
                     /locus_tag="RN951_002426"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDX2527416.1"
                     /translation="MQNAGSLVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKG
                     ANQAVAAGRSGANIAFIACTGDDSIGESVRQQLATDNIDITPVSVIKGESTGVALIFV
                     NGEGENVIGIHAGANAALSPALVEAQRERIANASALLMQLESPLESVMAAAKIAHQNK
                     TIVALNPAPARELPDELLALVDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEKGIR
                     TVLITLGSRGVWASVNGEGQRVPGFRVQAVDTIAAGDTFNGALITALLEEKPLPEAIR
                     FAHAAAAIAVTRKGAQPSVPWREEIDAFLDRQR"
     gene            32638..33630
                     /gene="rbsR"
                     /locus_tag="RN951_002427"
     CDS             32638..33630
                     /gene="rbsR"
                     /locus_tag="RN951_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose operon transcriptional repressor RbsR"
                     /protein_id="HDX2527417.1"
                     /translation="MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELN
                     YAPSALARSLKLNQTHTIGMLITASTNPFYSELVRGVERSCFERGYSLVLCNTEGDEQ
                     RMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
                     SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTG
                     DFEFNGGFDAMRQLLSHPLRPQAVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDI
                     ELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQLTPILMERGSA"
     gene            complement(33596..35023)
                     /gene="mdtD"
                     /locus_tag="RN951_002428"
     CDS             complement(33596..35023)
                     /gene="mdtD"
                     /locus_tag="RN951_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter subunit MdtD"
                     /protein_id="HDX2527418.1"
                     /translation="MSDKKKRSMAGLPWIAAMAFFMQALDATILNTALPAIAHSLNRS
                     PLAMQSAIISYTLTVAMLIPVSGWLADRFGTRRIFTLAVSLFTLGSLACALSNSLPQL
                     VVFRVIQGIGGAMMMPVARLALLRAYPRNELLPVLNFVAMPGLVGPILGPVLGGVLVT
                     WATWHWIFLINIPIGIAGLLYARKHMPNFTTARRRFDITGFLLFGLSLVLFSSGIELF
                     GEKIVASWIALTVIVTSIGLLLLYILHARRTPNPLISLDLFKTRTFSIGIVGNIATRL
                     GTGCVPFLMPLMLQVGFGYQAFMAGCMMAPTALGSIIAKSMVTQVLRRLGYRHTLVGI
                     TVIIGLMIAQFSLQSPAMAIWMLILPLFILGMAMSTQFTAMNTITLADLTDDNASSGN
                     SVLAVTQQLSISLGVAVSAAVLRVYEGMEGTTTVEQFHYTFITMGIITVASAAMFMLL
                     KTTDGNNLIKRQRKSKPNRVPSESE"
     gene            complement(35046..35738)
                     /locus_tag="RN951_002429"
     CDS             complement(35046..35738)
                     /locus_tag="RN951_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDX2527419.1"
                     /translation="MPLSAQQLAAQKNLSYVLAEKLAQRILKGEYEPGTILPGEIELG
                     EQFGVSRTAVREAVKTLTAKGMVLPRPRIGTRVMPQSNWNFLDQELLTWWMTEENFHQ
                     VIDHFLVMRICLEPQACLLAATVGTAEQKAHLNTLMAEMAALKENFRRERWIEVDMAW
                     HEHIYEMSANPFLTSFASLFHSVYHTYFTSITSDTVIKLDLHQAIVDAIIQSDGDAAF
                     KACQALLRSPDK"
BASE COUNT         8723 a         9232 c         9066 g         8890 t
ORIGIN      
        1 ctccgtcata acttgccctc taccgctttg cggcaaaact ccaaaaaaaa acctgaaaaa
       61 aacggcctga cgtgaatcaa gcaatttttt tcaggttttg cccgcttagt gcggtaacaa
      121 tcctttactc agtaataata tttcagtgtt ctttgcgcac gcgctctata tttatggcta
      181 aaaacataat ctctgcgggt gaaattttac gttgatactg caaaccaata aaaatggcga
      241 tccgttccgc acattgccat gcttgcgggt aattttgttt tactgcttgt tgtaatgatt
      301 catcactatc gttaattgaa gcatgttcaa gaatacgcca ggataaaaac ttcagatgtg
      361 taaccagtcg ctgataactc aagctttctt cctggtaatt aaggctgaac tgaaatttta
      421 ttaattgcag catttcgcgc attaactgcg tgacacctgc aacatcctcc atatttccgc
      481 tcatttgggc actgaccaga tgcatggcaa taaagcccac ttcatctttc ggtaactgca
      541 cgcccaaccg tttatcaata atggttaacg cttcttcccc tagctggaac tctttcgggt
      601 aaagccgctg gatatcccac agcaacgggt tgggcagcaa cacgttttgc tgaaagcgtt
      661 taatcgcaaa ctggcaatgg tcagttagcg agatataaat actgtcctgt aattttccca
      721 agcgctcctg cgctaaagag ataatacgat cacaggttgc catcacctca agaggaatat
      781 gacttaagag ttcgcttaat cgcccgttca gttcatgact gctcaaggca tactcttttt
      841 ctattccact tgagttaatt ctttcgccag cgcgtttttg aaagccaatt ccgcgcccca
      901 tgacgacttt ttcccgctgt tgatcatcaa taaccaccac aacattattg ttgagaattt
      961 tggtgatttg catgttcata gcaaggacct tttttataaa caaaaaaacc cgacttcacc
     1021 agtattctct ggttatgtca ggttttgcct gcgaatgcag taacaatcca gtcatttatt
     1081 aatggttttt ataacgaaca tccaggttcg gaaattaatt taattgcgtg cagagaaaat
     1141 agcaatgcgc tattgataaa aatatgacca tgctcgcagt tattaacttt gtgtaatttt
     1201 aggaatttat aaagttatat ataacaaatc ccaataatta agttattggg atttgtctgg
     1261 tgaattattt gtcgctatct ttccccgcca gcagtttatc cagctcatcg ccaccgacgt
     1321 gacggaaatc ctgccccttc acgtagtaga agataaactc acaaatattc tggcagcggt
     1381 cgccaatacg ttcgatagaa cgcgcgcaga acagcgcagt aagtacgctc ggaatggtac
     1441 gcgaatcttc catcatgtag gtcatcagtt gacgaacaat accttcgtat tcctgatcga
     1501 cttttttatc ttcacgataa atacgtaccg cttcgtcaat gtccatccgc gcgaacgcgt
     1561 ccagcacgtc gtgcagcatc tggatggtat gacggcccag cgactccaga cttaccagca
     1621 acggctgatg ctgctgggag aatttctcca gcgcagtacg gcagattttg tccgccacgt
     1681 cgccaatacg ctccagctcg gcaatggttt tactgatcac cataaccagt cgcaggtcgc
     1741 tcgccgtcgg ctgacgtttg gcgataatgc gcacgcaggc ttcatcgatc gccacttcca
     1801 tcatgttgac gttcttgtcg ccttcgatga cgcgcttcgc cagatcgctg tcctggttat
     1861 gcatcgcggt gattgcatca gaaagctgct gctccaccat gccgcccatg gtcatcacct
     1921 gcgtgcggat actttccagt tcggcgttga actggccgga aatatgttta ttaagattga
     1981 gactgtccat aacgcactcc tgaatcaacc gtaacgaccg gtgatgtagt cttctgtttg
     2041 tttcttcgct ggcttggtga acagatcgtc cgtgttgctg aactcaatca attcgcccag
     2101 gtacataaac gccgtgtggt cggaacaacg cgcagcctgc tgcatgttgt gggtgacgat
     2161 caccacggtg taatcctgct tcagttcggt gatcagctct tcaatacgcc cggtagagat
     2221 agggtcgagc gccgaacacg gttcgtcgag cagcagcact tccgggcgaa tggcgatacc
     2281 acgcgcaata cacagacgct gttgctgacc accagagaga gagtaaccgc tctggtgcaa
     2341 tttatctttg gtttcgttcc acaatgcggc tttggtcaat gcccactgca cgcgctcgtc
     2401 catgtcggca cgggagagct tctcaaacag acgaacgcca aaagcgatgt tgtcgtagat
     2461 ggacatcgga aacggcgtcg gtttctggaa caccatgccc actttcgcac gcagcagtgc
     2521 gatatcctga gagttggtca ggatgttgtc gccatcaagc agaatttcac cttccgcacg
     2581 ctgctccggg tacagttcaa acattttgtt gaaggtacgc agcagcgtcg atttaccgca
     2641 gccggacggc ccgataaacg ccgttacctg gtttttagcg atatccaggt tgatgttttt
     2701 cagggcatgg aatttgccgt agtagaagtt caaattacga acctgaattt tactcggggc
     2761 agtttcaacc atactcattg caatcttttc ctcatcgtgc ctgatgcact tcgctaatca
     2821 ggcttaccgt aggccggatc aggcgttcac gccgcatccg gcaaagtgtt aaccgtgtac
     2881 agagtcaaaa aggcgctcgg tcggtcccct cgcccctctg gggagagggt tagggtgagg
     2941 ggaaaaccgt gtcagcaata tcaaccgtgt ttattcttcg caaaaacaac gcgcgccaga
     3001 atgttcagca gcagtacgca cagggtaatg atcaataccc cggcccaggc caattgctgc
     3061 cattccgcaa acgggctcat cgcaaactta aagatcgtca ccggcaggtt ggcgatcggc
     3121 tgcatcatgt ccgtgctcca gaactggttg gagagcgcgg taaacagcag cggcgcggtt
     3181 tcaccagcaa tacgggcaat cgccagcagg ataccggtca taatcccgga caccgacgct
     3241 ttcagcgtaa tcgcagagat catcttccac ttcggtgtac ccagcgcata agccgcttca
     3301 cgcaggctgt acggcaccag tttcagcatg ttctcggtgg tgcggataac aatcggcacc
     3361 tgcaacaacg ccagggcaat cacgcccgcc cagccggaga agtgctccat ctgcgccacc
     3421 acaatggtgt aaacaaacag accaaccaca atcgacggcg cagagagcag aatgtcgtta
     3481 atgaagcgaa tcacttctgc cagccaggat ttacgaccat attccgccag ataaatcccc
     3541 gccataatgc ccagcggcgt accgaatacc gtggcccaca aaattaacag cccgctaccc
     3601 gccagagcgt tcgccagacc accaccttcc gtattgggcg gcggcgtcat ttcagtgaac
     3661 agcgccagcg acataccgtc gataccgcga gtgatggtgg acattaaaat ccagatcagc
     3721 cagaacaggc cgaaggccat cgtcgccatc gagagcgtca gcgcaatacg gtttttgagg
     3781 cggcgacgcg cctgcatttt gcggcgagat tcagccagcg ccgcagtggt ttgcatttca
     3841 accatagcca ttagcgtgcc ccctcattct tagccaggcg cataatcata aacttcgatg
     3901 cggcgaggac gatgaaggta atcacaaaca ggatcaggcc cagttccatc agtgcggcaa
     3961 cgtgcagacc ggattccgct tccgcaaatt cgttcgccag cgcagaggtg atactgttgc
     4021 ccggcatata cagcgaggcg ctgtcgagct ggtaggtgtt accgatgata aaggtcaccg
     4081 ccatggtttc accgagcgcg cggcccagcc ccagcatgat gccgccgata acaccatttt
     4141 tggtgaacgg aagaacgata cgccagataa cttcccaggt ggtgcagcca ataccgtagg
     4201 ccgactcttt catcatcacc ggggtttgtt cgaacacatc acgcattacc gccgcaatgt
     4261 acggaataat catgatggcg aggatcacgc ctgccgcgag gataccgata ccaaatgcgg
     4321 ggccagagaa cagcgcgcca acaatcggga tattcgacat gatattgccg accggctcct
     4381 gaaagtaaac ggcgaacagc ggcgcaaaga taaacaggcc ccacatgccg taaacgatac
     4441 ttggaatggc tgccagcagc tcaatggcga tacccagcgg gcgtttcagc cagccaggcg
     4501 caagctcagt caggaacagg gcgataccga aactcaccgg gacggcgatc agcagcgcga
     4561 taaacgaagt caccaacgta ccgtagatcg gcaccagcgc cccgtagata tcgttcggtg
     4621 catcccactc tttggtccat aggaaagcca gaccaaattt ctgaatgctc ggccaggagg
     4681 agatgatcag agagacaata atgccaccca acatcaatag cacaatcagc gccgccagtt
     4741 ttaccagcac gctgaaaatt atgtcgccct ttttacccgg tgggttaaaa gcaggcttgg
     4801 ttgcagccat aagttactct tcagttaaac gcgtttacaa agtcattttg taatgccgga
     4861 tgcggcgtaa aacaccgtac ccggcctgga gttttattag tacagcggct taccgctact
     4921 gtctttaata ttggtcttcc acgcagcgcg aacctgttca actacactat ccggcaggct
     4981 ggcgtaatcc aggtcgttcg cctgtttagc cccggttttg tacgcccagt cgaagaattt
     5041 cagcacttct gtgccttgtt ctggtttctt ctgatctttg tggatcagaa tgaacgtggt
     5101 agaggtaata ggccatgcat cttcgccttt ctggttggtc agatcctgag cgaaggtttt
     5161 gctccagtct gcaccttttg ctgcattagc gaagttttct tcggtcggac taaccggttt
     5221 accatcagcg gagatcagtt tggtgtacgc caggttgttc tgcttcgcgt aagcatattc
     5281 aacataacca attgcccccg gcagacgctg aacgaacgcg gcgataccgt cgttaccttt
     5341 accgcccaga ccgatcggcc attttacggt agagccagta ccaacgttgt ttttccactc
     5401 ttcgttcact ttcgccaggt agctggtgaa gacgaaggaa gtcccggagc catctgcgcg
     5461 gcgtactaca gcaatgtttt gtgaaggcag tttcagaccc ggattcagtt tggcgatggc
     5521 ttcatcatcc cacttcttga ttttgcccag gtagatgtcg ccgagggttt taccatccag
     5581 caccagttcg ccagacttca gccctggaat gttaaccgcc agcaccacgc cgccaatcac
     5641 ggtcgggaac tggaacagac cttcctgagc cagtttttcg tcagacagcg gcgcgtcaga
     5701 ggcaccaaaa tcaacggtat tagcgataat ctgttttacg ccaccggaag aaccgatacc
     5761 ctggtagtta actttattac cggtttcttt ctggtaagtg tcagcccatt tggcatacac
     5821 cggcgcaggg aaggttgcac ctgcacctgt caggcttgct tctgcaaaca cagagaaagc
     5881 actcatcgat aaggtcgcgg cgacaacagt tgcgacggtg gtacgcataa ctttcataat
     5941 gtctcctggg aggattcata aagcattgtt tgttggctac gagaagcaaa ataggacaaa
     6001 caggtgacag ttatatgtaa ggaatatgac agttttatga cagagagata aagtcttcag
     6061 tctgatttaa ataagcgttg atattcagtc aattacaaac attaataacg aagagatgac
     6121 agaaaaattt tcattctgtg acagagaaaa agtagccgaa gatgacggtt tgtcacatgg
     6181 agttggcagg atgtttgatt aaaaacataa caggaagaaa aatgccccgc ttacgcaggg
     6241 catccattta ttactcaacc gtaaccgatt ttgccaggtt acgcggctgg tcaacgtcgg
     6301 tgcctttgat cagcgcgaca tggtaagcca gcagctgcag cggaacggtg tagaagatcg
     6361 gtgcaatcac ctcttccaca tgcggcatct cgatgatgtg catgttatcg ctacttacaa
     6421 aacccgcatc ctgatcggcg aagacataca actgaccgcc acgcgcgcga acttcttcaa
     6481 tgttggattt cagtttttcc agcaattcgt tgttcggtgc aacaacaata accggcatat
     6541 cggcatcaat tagcgccagc ggaccgtgtt tcagttcgcc agcagcgtag gcttcagcgt
     6601 gaatgtaaga gatctctttc aacttcaatg cgccttccag cgcgattggg tactgatcgc
     6661 cacggcccag gaacagcgcg tgatgtttgt cagagaaatc ttctgccagc gcttcaatgc
     6721 gtttgtcctg agacagcatc tgctcaatac ggctcggcag cgcctgcaga ccatgcacga
     6781 tgtcatgttc aatggaggca tccagacctt tcaggcgaga cagcttcgcc accagcatca
     6841 acagcacagt taactgagtg gtgaatgctt tagtggatgc cacgccgatt tctgtacccg
     6901 cgttggtcat tagcgccaga tcggattcgc gcaccagaga agaacccgga acgttacaga
     6961 ttgccagtga accaaggtaa cccagctctt tcgacagacg caggccagcc agggtatccg
     7021 cggtttcgcc agactgtgac aaggtgatca tcaggctgtt acgacgcacg gcagatttgc
     7081 gatagcggaa ttcagaggcg atttcgacgt cgcacggaat acctgctagc gattcaaacc
     7141 agtagcggga aaccataccg gagttataag aagtaccaca ggcgaggatc tgaatatgct
     7201 caaccttcga cagcagttcg tcggcgttcg gtcccagctc gcttaaatca acctgaccgt
     7261 ggctgatgcg tccggtaagg gtgtttttga tcgcgttcgg ctgttcgtag atctctttct
     7321 gcatgtagtg acggtaaatg cctttatcgc ccgcgtcata ttgcagattg gattcgatat
     7381 cctgacgttt tacttccgcg ccagttttat cgaagatgtt taccgaacgg cgagtgattt
     7441 ccgcaatatc gccctcttca aggaagataa agcgacgggt caccggcaac agcgccagct
     7501 ggtcagaagc gataaagttt tcgcccatcc ccaggccaat caccagcgga ctaccagaac
     7561 gtgccgccag cagggtatcc gggtgacggg agtccatgat cactgtaccg tacgcaccac
     7621 gcagctgcgg gatagcacgc agaacggcct cacgcagagt cccgccttgt ttcagctccc
     7681 agttcaccag atgggcaatc acttcggtgt cggtttcaga aacgaaggta tagccacgcg
     7741 cttttagctc ttcacgcagc ggttcatggt tttcgatgat gccgttatgc accaccacaa
     7801 tgtgttcaga aacatgcgga tgcgcattca cttctgaagg ttcaccgtgg gtcgcccagc
     7861 gagtgtgagc aataccagtg ccgccatgca gaggatgttc ttccgctgcc tgtgccagca
     7921 tctggacttt accgaggcga cgcaggcggg tcatatgacc ttctgcatca acaacggcca
     7981 gaccggcaga gtcatatccg cggtattcca gacgacgtaa accttcaaga aggatttctg
     8041 ctacatcacg ttgcgcgatc gcgccaacaa ttccacacat agtttttgat tccgatttat
     8101 atcgttgtcg gtcaacctgt atgcccgttt tttcgggcgc cccgagcctt gtagagagtg
     8161 gggttatttt tatagttact gcttgtggga gggagattat gttatctcct catcccatgt
     8221 gaccgggtta gccggccaga atcacttttt ctttaccgga cgacgccagc cttctttctg
     8281 agtctgcggc acacggctga tagctaatgc attttcgccg acattacgcg tcacagttgt
     8341 acccgcagca atggtcgcgc ctttgcctac tgttaccggg gccaccagct gagtgtcgga
     8401 accaacaaac acatcgtcgc cgataatggt cttaaattta ttcgcaccat cgtagttgca
     8461 ggtaatggtt cccgcgccga tgttaacgtt atcgccaatt tccgcatcgc ccaggtaagt
     8521 cagatgacca gctttcgagc ctttacccag acgcgctttt ttcatctcaa cgaagttacc
     8581 gacgtgagca ccttccagca actcagcacc aggacgcaaa cgggcaaacg ggccaatggt
     8641 acaggccgct gccagattcg catcttccac aacggtatac ggactgattt cgcaatcatc
     8701 gccaatcacg ctgtttttaa tcacgcaacc ggtgccaatt ttcacgcgat gaccgagagt
     8761 cacgttgccc tcgatgataa cgttagtatc aatttcaaca tcgcgcccgt gagttagcgt
     8821 accacgcaga tcaaaacgcg ctggatcgcg cagcataacg cctgctaaca gcagtttttc
     8881 agcctgttcg gactgataaa cacgctccag acgggagagt tgcaggcggt tattcacgcc
     8941 ttctacttcg cttaaacgtt gcggatgaac ggcgacgatt tcacgccctt cctgatacgc
     9001 cagcgcaata atgtcggtga tgtagtattc gccctgagca ttattgttgg tcagcttcgc
     9061 cagccagcgt ttcatatctg cgccgttggc aatcagaatg ccggtgttga tctcctgaat
     9121 ctgacgctgc tcgtcggtgg catctttgtg ctcaacaatg ccggtaactt tgccgttttc
     9181 acgggtgata cgtccataac cggtcggatc atccagtttc accgtcagca gaccaatgcc
     9241 accctgcggt ttagcatcac gcagacgctg gagtgtttcg acagagatca gcggcacgtc
     9301 gccgtagagc attaaaatgt cttcatcatc ggcaaagaaa ggtgcggcct gctgcattgc
     9361 atgacccgta cccagctgct ctgcctgaag cacccagtta aggttgtcgt ctttcagcgc
     9421 ctgttttagc agatcgccgc cgtgaccgta caccaggtga acgtgcgctg cgcctaattc
     9481 attcgcagca tcaatgacat gctgaaccat cgctttcccg gcaagggtat gcagcacttt
     9541 cggaagatcg gaatacatgc gcgtgccttt gcctgcggca aggatcacta cgctcatagc
     9601 attattcaac atacgcgtcc tgactgtaat ttgagaacga atttaaaccg cttcaccttg
     9661 aaaaaactac atttttttca tcgtgaaatg gacagaggat aaattgttca ataacggatt
     9721 atccccgctg acgaaagcgc cattttcgac catcgtcacg ccttttgtct gcagaaaatt
     9781 aaggcagtac cttaatttaa gcgtcaggtg gatgtttttg ctcttatttc gatcaatgaa
     9841 taaacaggaa aacagggggt tttatatcag caggatctat gtgaacgcta ttcaggacgg
     9901 gtcacacgcg caaaaaaaag ccagcctgtt tccagactgg cttttgtgct tttcaagccg
     9961 gtgttacatc gcttttttgg tcaactcgat aacgcgcagc tgcgcgatcg ctttggccag
    10021 ttccgcagac gcctgagcgt aatctacgtc gccgtgagag ctgctaatgt gctcttcagc
    10081 cttacgtttc gcttccatgg ctcgcgcttc gtcgagatcc tggccgcgaa ttgcggtgtc
    10141 ggccagaacg gtcacgttgc caggctgcac ttcaagaatg ccgccagaca gatagataaa
    10201 ctcttcgtga ccgtgctgtt tcacgatgcg aatcatacca ggcttaatgg cggtgagcag
    10261 cggtgcgtgg ccagggtaga tccccagttc accttcgcta cccgttacct ggattttctc
    10321 gaccagacca gagaacattt gttgctctgc gctgacgacg tccaggtggt aagtcattgc
    10381 catatcaccc tccgattaag gcgttaaagt tttttggctt tttccacagc ttcttcgatg
    10441 gaaccgacca tgtagaacgc ctgctccggc aggtgatcgt attcgccttc catgatgcct
    10501 ttaaagccac ggatggtgtc tttcagggag acgtatttac ccggagaacc ggtgaatact
    10561 tctgccacga agaacggctg ggacaggaag cgctggatct tacgagcacg cgctaccacc
    10621 agtttgtctt cttcagacag ttcatccata cccaggatgg cgatgatgtc tttcagttcc
    10681 tgataacgtt gcaggatgga ctgaacgcca cgcgcggtgt cgtagtgttc ctgaccaacc
    10741 accagcgggt ccagctgacg gctggtggag tccagcgggt caacggccgg gtagataccc
    10801 agagacgcga tctgacggct cagtaccacg gttgcgtcaa ggtgcgcaaa ggtggttgcc
    10861 ggagacgggt cagtcaagtc atccgcaggt acgtatactg cctgtacgga ggtgatagaa
    10921 ccagttttgg tggaggtgat acgttcctgc agaacgccca tctcttccgc cagggtcggc
    10981 tgataaccta ccgctgaagg catacggccc agcagtgcgg atacttccgt accggccagg
    11041 gtgtaacgat agatgttgtc aacgaacagc agaacgtcac gaccttcgtc acggaatttc
    11101 tcagccatgg tcagaccggt cagagcaacg cgcagacggt ttcccggcgg ctcgttcatc
    11161 tggccataca ccagggatac tttgtcgata acgttggagt cggtcatttc gtggtagaag
    11221 tcgttaccct cacgagtacg ttcacctacg cccgcaaaca cagagtaacc ggagtgctcg
    11281 atcgcgatgt tacgaatgag ctccatcatg tttacggttt tacctacacc cgcaccaccg
    11341 aacagaccaa ctttaccgcc cttagcgaac ggacacatca ggtcgataac tttgataccg
    11401 gtttccagca gttcctgaga gtttgacagc tcttcgtagg aaggtgctgc gcggtgaatc
    11461 gcccaacgct cttcttcacc gatctcgcct ttcatgtcga ccggttcacc cagtacgttc
    11521 atgatacggc ccagagtcgc tttacctacc gggacttcaa tcgggtgttc gaggtctttt
    11581 acatccagac cgcgacgcag accgtcggag gaacccattg cgatggtacg tacgataccg
    11641 ccgccgagct gctgctgaac ttccagcacc agacgctcat taccattttg cacctcaaga
    11701 gcatcgtaca cgcgcggtac ggcatcctga gggaattcga cgtcaactac ggcgccgatt
    11761 acctggacaa tctttccagt agccatctta aatcctctac gaaataacct gtttaaaccg
    11821 cggcggcccc cgagacgatc tcggtgagtt cctgagtaat gctggcctga cgagctttgt
    11881 tgtataccaa ctgcagctct ttaatcaggc tgccgccatt gtcggtcgcg gctttcatcg
    11941 ccaccatacg ggcggcctgc tcgctggcca ggttttcaac cacgccctga taaacctgag
    12001 attcgacata acgacgcagc agggtatcca gcaacgcctt cggatcgggt tcgtacaggt
    12061 aatcccagga tttatgtttc agatcatcat catctgatgc cggtaacggc agcagctggc
    12121 tgatggtcgg aacctgagac atggtgttaa taaatttgtt gctgacaatg taaagcttgt
    12181 ccagacggcc ttcgtcgtag gcctgcaaca tcacttttac cggaccgatc agttcggaca
    12241 gggaagggtt atcccccatg ccggtgacct gggcaacaac attgccgccc acggagttga
    12301 agaacgacac gcctttcgag ccgatcattg cgaggtcgca ttgaacgcct ttgtcggtcc
    12361 aggtcttcat ttccgccagc agttttttga acaggttaat gttcaaacca ccgcacaaac
    12421 cacggtcggt cgacaccacc aggtagccca cgcgtttaac gtcgcggtct tccaggtaag
    12481 ggtgcttata ttccagatta ccgtgtgcaa ggtgaccaat cactttgcgc atggtttctg
    12541 cataaggacg gctggccgcc atgcgatcct gcgatttacg cattttggaa gcggcgacca
    12601 tctccatcgc tttagtgatc ttttgcgtgt tctggacgct tgcgatctta ctacgtatct
    12661 cttttgcgcc ggccatgagc ttctcctcaa tgccttgcgg cctgccctaa ggcaagccgc
    12721 cagacgttac caggattggg ttgctttgaa ggaatcgagg atgcctttca gcttgccttc
    12781 gatttcgtcg ttgtagccac cggtctggtt gatctcttgc atcaacggag cgtgatcacg
    12841 gtcgacgtaa gccagcagag cggcttcgaa gctgccaatt ttcgacagtt caacatccgc
    12901 caggtaacca cgttctgctg cgaacagaac cagagactgc tgcgcaacgg acatcggcgc
    12961 atactgtttc tgtttcagca gttcggtcac tttctgaccg tggtcaagct gcttacgtgt
    13021 tgcatcgtca aggtcggatg caaactgaga gaacgctgcc agttcacgat actgtgccag
    13081 agcggtacgg ataccaccgg acagtttttt catgatcttg gtctgtgctg caccaccaac
    13141 acgggatacg gaaatacccg ggttaaccgc aggacgaata ccggcgttga acaggttggt
    13201 ttccaggaag atctgaccat cggtaatgga gattacgttg gtcggaacga acgcagaaac
    13261 gtcacccgcc tgagtttcga taatcggcag tgcggtcaga gaaccggttt tccctttcac
    13321 ttcacctttg gtgaaggctt caacgtattc ggcgttaaca cgtgcagcac gctccagcag
    13381 acgagagtgg aggtagaaaa cgtcgcccgg gaatgcttca cgtcctggcg gacgacggag
    13441 cagcagggag atctgacggt aagcaacagc ctgtttagac aggtcatcgt aaatgatcag
    13501 cgcatcttca ccgcggtcac ggaagtattc gcccattgcg caaccggcat acggtgccag
    13561 gtattgcagt gcagcggatt cagacgcggt tgctaccaca acgatggtgt tagccagtgc
    13621 gccgtgctct tccagtttac gtaccacgtt agaaatggtg gacgctttct ggccgatagc
    13681 gacatagata catttgatac cggaatcgcg ctggttgatg atggcatcga tagccagtgc
    13741 ggttttacct gtctgacggt caccgatgat caattcacgc tgaccacgac cgattgggat
    13801 catggagtca acggctttat aaccggtctg taccggctga tctacggact gacgttcgat
    13861 aacgcccgga gcgattgctt ctacagcaga gaagccgtcg tgatccagcg gacctttacc
    13921 gtcgattggt gcacccagag tgttaaccac acggcccagc aggccacggc caaccggaac
    13981 ttccaggata cggccagtac acttaacttt catgccttcg gcaaggtcag cgtacggacc
    14041 cataacaacc gcacctacag agtcgcgctc gaggttcagt gcgatagcgt aacggttacc
    14101 cggcagggag atcatttcac cctgcataca atcggccagg ccgtgaatgc ggataacacc
    14161 gtcacttaca gaaacaatag taccttcgtt gtgagcttca ctcacaacat tgaactgagc
    14221 aatgcgctgc ttgatcagtt cgctgatttc ggtggaattc agttgcatgc tccagtcccc
    14281 ttaagactgc aagacgtctg caaggcgctc aagacgaccg cgtacgctgc catcaatgac
    14341 catatcaccc gctcggatga taacgcctgc cattacagac ttatcgattt tgcaattcag
    14401 cttaactttg cgtgacagac gtttttccat cgcagcagaa attttcgcga gctgttgttc
    14461 actcagtgcg gcagcggaaa tgacgtctac ctcagcggta gcctcactca cggcacgcag
    14521 gtgaataaac tgctccagaa catccgggag cgcgttaaga cgaccatttt cagccataac
    14581 ccgaatcagg ttctgaccgt tttcgtccag ttgctcacca caaactgcga taaacgactc
    14641 ggcgagcgtt tctggcgcaa gcgcgccaga gagaagctct gccatttgtt cgtttttggt
    14701 tacctcggcg gcaaacgcca gcatgtcctg ccagcgttct acactttggt gttcgacggc
    14761 aaagtcaaaa gctgctttgg cgtaggggcg agctaccgta ataaattcag acatcagccc
    14821 ctccctcctt acagttcagc gacaagttta tccacgatgt cgctgttagc agcttcatcc
    14881 acggaacgtt cgatgatctt ctcggcgcca gcaacagcca ggatagcaac ttgcttacgc
    14941 agctcttcac gggcacgttt acgctcggct tcaatttccg cctgcgcctg ggccacgatt
    15001 ttagtacgtt cctgttctgc ctcagctttc gcttcgtcca gaatctgcga gcggcgtttg
    15061 ttcgcctgct cgatgattac ctgggcttcc gctttcgctt ttttcagctg gtcggtcgcg
    15121 ctggcctttg caaggtcaag gtccttatgt gctcgttctg cggaagcaag gccgtcagca
    15181 atttcttttt gacgtttttc gatggctgcc attaatggcg gccatacgta cttcatgcag
    15241 aacagaacga acaggacaaa cgcgatggcc tggccgagga ttgttgcgtt aagattcaca
    15301 gcacaatgcc tctatttagt taacgttctg atattgctct ttaaataaaa gcaacgctta
    15361 ctacgcgaca gcgaacatca cgtacagacc cagacctaca gcgatcatcg ggatagcatc
    15421 caccagaccc ataacgataa agaactgagt acgcagcaga ggaatcagat caggttgacg
    15481 cgctgcgcct tccaggaatt tacccccgag gatgccgata ccgatcgcag caccgattgc
    15541 cgccagaccc atcatcacag cggcagccat gtacagcaga tccatattca ggttttccat
    15601 gacagtctcc agtttgtttc agttaaaacg tagtagtgtt ggtaaattaa tgttcttcag
    15661 acgccatcga cagatagacg atcgtcagaa ccatgaagat gaaggcttgc agcgtaatga
    15721 tcaggatgtg gaaaatggcc cacggcacat tcaggatcca ctgtgaccac cacggcaaca
    15781 gaccagcaat cagaatgaaa atcagctcac cggcatacat gttaccgaac agtcgcaaac
    15841 cgagtgaaac tggtttggac agcaggctta ccccttcaag gattaagttg acaggaatga
    15901 acgcccagtg attgaacggc tgcagcgtca actctttcgt gaagccgccg atgcctttca
    15961 ttttgatgct gtagaacaga atcaggataa atacgcccag tgccatagac agcgttacgt
    16021 tcacgtccgc agacggaacc acacgcagtg caggcagacc cagtacatgt tcagcaatgt
    16081 acggcagcag gtcgataggc agtaaatcca tcaggttcat caggaatacc cagacgaaga
    16141 tcgtcagggc cagcggagca atcagcttgc ttttgccatg gtacatgtct ttcacgctac
    16201 cattaacaaa gccgatcacc agctcaatcg cggtctgaaa cttacctggc acaccgctgg
    16261 tcgccttttt ggctacgcta cggaataaaa ccaggaacaa cagacccagc accaccgaga
    16321 agaacatgga gtcaatattg attgtccaga aggtggctgg ggggttttgt ggatccacca
    16381 gcgagaatgt acgcaggtcc agctgaaggt tattcaggtg gtgtcctatg taatcctgcg
    16441 gcgtcatatt ttctgaagcc atgatgcctt ttaccctttg ttgttaatta cagccggtgc
    16501 cagtatctga accaccagca ccaaaaccca cgtaacgatc agcggcaaga ataccgcctt
    16561 taaaaccgcc aacgccacca ccagtaacac caacatcgcc agaactttga aagcttcgcc
    16621 aaatgcgaat gtccaggcca cccggccttt cgctggtgta tgcgcctggt gacgccaggc
    16681 aaatatcata aacaaaacgt taggcagaaa gactgccagg cccccgctta ttgcagagac
    16741 gccccagaag gggtctttga ggctgaacag caatccactt gctatcacca ccagtaactg
    16801 aacgagcaga agcttccgag caacgtttcg actcacgagc gacacagaca tcacgttttt
    16861 cactcctgct cccttcgagg tatgccgcgt gtcgtataaa actttcttta aggcttagag
    16921 tcaagcatca aaaagcggtc aaattatacg gtgcgccccc gtgatttcaa acaataagta
    16981 gccaaaaggt gaataaatgt ttaaatattt ttccagtgca tacaattgcg acttttctgc
    17041 taaccctgtt cgatcatgaa aaactgtaaa taacgcgtaa acactggtga taaagcgtgc
    17101 ttcagatcac atattgcgca tgttcgcgca cagcatattt atttacttgg caaatgatgc
    17161 ctttgcaagt ttatgatatt tcagtctaaa aacagatact gttttaataa atgacattta
    17221 cacaacaaaa accacccatt gacattttta ataatgtttt aacagccaat gatggttctt
    17281 agcgccgatt tttagcagac tgatattttc actaatgact tattttctgc ttaccaaaaa
    17341 aagccacgtt atcttgttga tgcaaaagag tgaacgtggc gttaaatgta accagttata
    17401 tcagtagaaa acctggttgt tgttaacagt ctaaccggtc aattttttat gatttttttg
    17461 ataaaaatta aattttattt gctttaatca ccaccagatg acgttcgcca tccagggctg
    17521 gaacctgaag tttaaccact gattcgacct gatattcttc gggcaacaaa gcgatttcat
    17581 cttccggcat ttgccctttc agcgcgtaga aacggccttg ctcaccagga agatggtggc
    17641 accagctcac catatcgttc agagaggcaa aagcgcggct aattacgcca tcaaatggcg
    17701 gctctgaagg aaactcttct accctgctct gtactggttc aatattctcc agtttaagct
    17761 catgttgcac ctgacgaagg aaacgcacgc gtttaccaag gctatccaac agagtgaaat
    17821 gggcttcagg acgcacgata gagagtggaa tgcctggcag tcctggtccg gtgccgacat
    17881 cgataaaccg ttcaccttgc agatacggtg ccaccacaat gctatcgaga atatggcgta
    17941 ccagcatctc attaggatcg cggaccgaag tcaggttgta cgctttgttc catttatgca
    18001 gcatattcac gtaggcaata agctggtttt tctggtgatc ggtaagcgaa atacctgcgt
    18061 ctttcagcag taaggagagt ttgttgagca cggtgattac ctgttcttga tgcgttgcct
    18121 ggtaagcggg tgcttaccag gcatttttaa tgcgttatgc gctacgacgc agcataccct
    18181 gttttttcag ccacaccagc agaatggaga tggccgcagg cgtgacgcca gaaatacgcg
    18241 aagcttggcc gatagaggct ggtttgtgat cgttaagttt ggcgatcact tcgttagaaa
    18301 gaccggatac ctggcggtaa tccagtgtcg cgggtagcag ggtgttctcg ttacgcagct
    18361 gcttttcgat ctcatcttgc tggcgcgcga tataaccttc gtatttaacc tgaatctcaa
    18421 cctgttccgc cgcctgttcg tctgtcaacg aaggggcaaa cggcgtcagc gtggttaatt
    18481 tttcataagt catttccgga cgacgcagca gatcttcacc actggcttca cgggaaagcg
    18541 gcgcagtcag gtgagcattc acttcggctg cagcttccgc cgacggggtt acccaggtcg
    18601 atttcagacg ctgacgctca cgctcgatat tctcaagttt ctcgttaaag cgcgcccaac
    18661 gttcgtcatc caccaggccc agttcacgac cgatttcagt caaacgcaga tccgcattat
    18721 cttcgcgtag catcagacga tattctgcgc gcgaagtaaa catacgatac ggttctttgg
    18781 ttcctaaagt gcacaggtca tcaactagta cgccgagata cgcctgagaa cgtgccggag
    18841 cccaaccttc tttgtcagca gacagacggg cagcgttaag accggccagc aaaccttgcg
    18901 cagcggcttc ttcgtaaccg gtagtgccgt taatctgacc agcaaagaac agcccctgga
    18961 taaacttgct ctccagcgtc ggtttcaggt cgcgaggatc gaagaagtca tactcaatgg
    19021 cataacccgg acgcacgatc ttcgcgtttt ccatcccctg catagagcgg acgatttgca
    19081 tctgcacatc gaacggcagg ctggtggaga taccgttcgg ataaatttca ttagaggtca
    19141 gtccttccgg ttcaaggaag atctgatgct gatttctgtc ggcgaagcgc atgactttgt
    19201 cttcgatcga cgggcagtag cgtgggccga caccttcgat cacccctgcg tacattgggc
    19261 tacgatcgag gttactgcgg atcacatcat gggttttctc gttggtatga gtgatataac
    19321 acggcacctg ctggggatgc tgggacgcat tgcccataaa cgagaatacc ggcattgggt
    19381 tatcgccatg ctgttgcgcc agtacgctaa agtcgatggt tcgagcatca atacgcggtg
    19441 gtgtcccggt tttcagacga ccaacgcgca gcggcagttc acgcaaacgg cgagaaagcg
    19501 gaatggacgg cggatcacca gcacggccac cgctgtaatt atccagaccg atatgaattt
    19561 taccgtcgag gaacgtccca acggtgagca cgacggcttt ggcacggaac ttcagtccca
    19621 tttgggtaac agcaccgacc acgcgatcgt tttcaacaat aagatcttca accgcctgct
    19681 ggaagatcat caggttcggt tggttctcca gcgccgtacg taccgcctga cggtagagca
    19741 cacgatccgc ctgagctcgg gtagcgcgaa ccgccggtcc tttgcttgcg tttagtatcc
    19801 taaactggat acccgcctga tcgatcgctt tcgccatcag accgccgagt gcatccactt
    19861 cttttaccag atgtcccttc ccaataccgc cgatcgccgg gttgcagctc atctgcccca
    19921 gagtgtcgat attgtgtgtc aaaagcagag tctgttgacc catacgcgcc gcggccatcg
    19981 cggcctcggt gcctgcatga cccccgccaa tgatgatgac gtcaaaagga tccggataaa
    20041 acatggtgat tgcctcgcat aacgcggtat gaaaatggat tgaagcccgg gccgtggatt
    20101 ctactcaact ttgtcggctt gagaaagacc tgggatcctg ggtattaaaa agaagatcta
    20161 tttatttaga gatctgttct attgtgatct cttattagga tcgcactgcc ctgtggataa
    20221 caaggatccg gcttttaaga tcaacaacct ggaaaggatc attaactgtg aatgatcggt
    20281 gatcctggac cgtataagct gggatcagaa tgaggggtta tacacaactc aaaaactgaa
    20341 caacagttgt tctttggata actaccggtt gatccaagct tcctgacaga gttatccaca
    20401 gtagatcgca cgatctgtat acttatttga gtaaattaac ccacgatccc agccattctt
    20461 ctgccggatc ttccggaatg tcgtgatcaa gaatgttgat cttcagtgtt tcgcctgtct
    20521 gttttgcacc ggaatttttg agttctgcct cgagtttatc gatagcccca caaaaggtgt
    20581 catattcacg actgccaata ccgattgcgc caaagcggac tgcagaaaga tcgggcttct
    20641 gttcctgcaa tgcttcatag aaaggagaaa ggttgtccgg aatatctccg gcaccgtggg
    20701 tggagctgat aaccagccag atccctgagg caggtaaatc ttctaacagc ggaccgtgca
    20761 gcgtttcggt ggtaaaaccc gcctcttcca gcttttcagc caggtgttct gctacatatt
    20821 cggcaccgcc gagggtgctg ccgctgataa gagtgatatc tgccataaac cgccaccttt
    20881 attaagagtg gcgtattgta cgctgtgaac gcgttgggat ctacctgtgg aaaagtatgg
    20941 gattaaaaaa gccgatcagg gcttgatggt acgcatgatc gggttttgca ggacgatcaa
    21001 tgtctcggtg gactgaattt catcaattgt ttggatcttg ttgataagta catgctggag
    21061 agcgtcgatc gaacggcaca tcacttttat aaagatgctg tagtggccgg ttgtgtaata
    21121 ggcttcagtg acttcatcaa ggctttccag ctttgccagc gcggaagggt agtctttggc
    21181 gctctttaat ataatgccga taaagcagcc tacgtcataa ccgagctgct tcgggctgac
    21241 atcaatacgc gccccggtaa tgatccccgc ctgcttcatt ttctctactc gaacgtgaat
    21301 cgtccccgga ctgacgccaa attgtttcgc cagttcggcg taagcggtgc gcgcattgcc
    21361 cattaatgct tccaggatgc cacggtccag attgtcgatc agataatttt ccataggatt
    21421 ttcttatgcg gattgatgat tcattctatt ttagccttct tttttaatga atcaaaagtg
    21481 agttaggctt tttattgaat gattattgca tgtgtgtcgg tttttgttgc ttaatcataa
    21541 gcaacaggac gcaggagtat aaaaaatgaa aaccgcttac attgccaaac aacgtcaaat
    21601 tagcttcgtg aaatctcact tttctcgtca actggaagaa cgtctggggc tgatcgaagt
    21661 ccaggcgccg attcttagcc gtgtggggga tggcacgcag gataacttgt cgggctgtga
    21721 aaaagcggtg caggtaaaag tgaaagctct gcctgatgcc cagttcgaag tggttcattc
    21781 actggcgaag tggaaacgtc agaccttagg gcaacacgac ttcagcgcgg gcgaagggct
    21841 gtacacgcac atgaaagccc ttcgccccga tgaagaccgt ctttctccgt tgcactcggt
    21901 ctatgttgat cagtgggact gggaacgcgt aatgggcgac ggtgagcgtc aattctcgac
    21961 tctgaaaagc acggtagagg cgatctgggc gggaattaaa gcaaccgaag ctgcggttag
    22021 cgaagagttt ggcctggcac cgttcctgcc ggatcagatc cacttcgtac acagccagga
    22081 gttactgtct cgttatccgg atcttgatgc caaagggcgt gagcgggcga tagcgaaaga
    22141 tcttggcgcg gtattccttg tcgggattgg cggcaagctg agcgatggtc atcgccacga
    22201 cgtgcgcgca ccggattatg atgactggag caccccgtca gagctgggcc atgcgggtct
    22261 gaacggcgat attctggtgt ggaacccggt actggaagat gcgtttgagc tttcctccat
    22321 ggggatccgt gtagatgccg acacgctgaa gcatcaactg gcgctgaccg gtgacgaaga
    22381 tcgcctggag ctggagtggc atcaggcgct gctgcgcggt gaaatgccgc agaccatcgg
    22441 cggcggtatc ggccagtctc gtttgactat gctgctgctg caactgccgc atatcggcca
    22501 ggttcagtgt ggagtatggc cagctgctgt tcgcgagagc gtcccttctc tgctgtaata
    22561 atttatcgcc gccagcgtct gagcaggcgg cttcgcatcc cggtatcaaa gcgccagata
    22621 tgatcgaaaa tgcgcatgat gccgggtttg ccgtgtgccg acatcgccac ggcatgaaag
    22681 cgatgctgat gtacccgctg cagctctttc actttactcg tcacgtcgtc aggcaaccgc
    22741 tgagcgataa aatcagaaat caccaccgca tcggcatcaa accattccct gctttgcaag
    22801 cgttccataa tggcgcgaaa acaactggca agatcggtgc cgccacgaaa ctgctggctt
    22861 aaaaaacgga ttgcttgttc gatgccttgt gggcctgaaa gctcataacg gacgatctcg
    22921 gtggaaaata gcataatata gcagcgccgg ttttctgcga gagcaatgcg catcaaggcc
    22981 aggcagaacg ctttcgcaca ctgttcatta aagccgccca ttgagccgga agtatccaca
    23041 cagacaataa acggcccgcg cggctgttca tcgtaatctt tatgtaccac cggacgttcg
    23101 atcacttttt cacgccacga ctcaccgtgc aggcgatagg tgagcaactg tttttccacc
    23161 agccgacggt aaaactcata ctccagttcc gttatcccta gtgtcgccag ttctggcggc
    23221 aggagacgta aaatatcatc gctttgttgc agaccatcaa cctgctcagg aaccgtcgcc
    23281 ggttcgcgca ccatggtgcg gaaggtttcc atctgcgcat cgttgcgcgg tattgatttg
    23341 gcttcccgag aacgccccag ctgctctgcc aggcgtttca gttccggctg ttcgttaaga
    23401 aattcaccgt atttcacaat caactgatag tcgccacgtt taagctgacc ggcgctcata
    23461 tcccacagac gaccagctgc agtattgtta tctgcgagaa tcggttcaag ttgtccgctc
    23521 agcgtcatgc gttcctgaac ttcactcaac agttgttcgc gttcttcttc taatagctgt
    23581 tgatttaacg tcgttgcttg cacgatcaga cttaaacgcc aacgctggag aaaaagcgtg
    23641 tgtaacgctg aagtgatcgt gctgttagca tcaaccaact gtcgggcttg ttctgcccat
    23701 ggagaattca gacgatgcag taagtccagg atctgtggta gctgcacaat aaactgtggc
    23761 gtggagagga gctggctttg ctgatagcac atcacctctt cggtgagttc cggcgggact
    23821 cgggcatctt tcagccgact gcgcagcgct tcacgccagc ggggaacatc atcagtgatt
    23881 gccgccttca ggcgtgggaa tttttcaaag aagaccgcca gctgcggtga ggccagcagt
    23941 gcgatgatca tctcttcgat caatccctct tcgctgacgg ccagcatcac attaagcgta
    24001 tccagcgtta gcattgttgt gcctggcgaa tctgtgcacc gacatcctgt aggctggctt
    24061 caatgcgacc taaccagtcg ccagggataa acagacattt ttgctgttcg ctgaataaag
    24121 cgtgttgctt gcgccagtcg ctttcaagct cttccagttg ttgttttatt tcaccaggca
    24181 gaccttcagc cgatgaaccg ggaagtgcca gcgtactgcc ttgtaaactt acatcgcgaa
    24241 cgacaagatg ttgggcgcta tcaacttcca gattcagttt ctgggcaaag ccgataccgt
    24301 tcagtttacc gcgaatttca ccacctttgc tcagccactg ttccagcgcg ctacgctcaa
    24361 aggagatatg aaccacttcc atatcatgca gttttaacgg tttttgcagc agtagagtca
    24421 gagtggaagc agtaacgtta acaggaagtt gatactgctg acgacggctg aaaatgccgc
    24481 ccagacgaat taccgttaag gctgttttat cgctttgttg ctgctggagt tgcaggtgac
    24541 gttgcacaat cgcgccaagg cgagtcaaca tcccttgctg ttgccaggcg tgaccggtca
    24601 tcaatacatc aatttgttgt tgtatcaaat tcaggctttg cgcgtcatac cacaggcaat
    24661 ctttcagcaa aatgagatct accggggtaa cagcactgcg accgctaaaa aaggcgctgg
    24721 cctgcaataa tcggatcgct tttttccagc gacgatccga gacataaggc gcatccggta
    24781 atttatccag ttgctggcgc agcataaaaa tcagctcaaa tacatgatcg ggcagcgtaa
    24841 tttcaccaat ctctttctgc cagcgttcat attcttcatc tgtgacctgc aaggcatcag
    24901 gaaccggatt gtcgttttca tcctgttgac tggtcagcat ggagcggaaa ttcgctttat
    24961 cctgcacttt atctaaccac agacgaatca gcatgcggtc atataacgct tccagactgc
    25021 tgtctgcttc cggcagctcg ttggaggccg ccaccagcag acgcattggg attttttcta
    25081 cgtgtgcacc gttgcggaac tggcgctcgt taatggcggt gagcaaggta ttaagaattg
    25141 ccgggcccgc tttccagatc tcatccagaa agacaatttc tgcttccggc aggtaaccgc
    25201 tggttaaacg ttcatagcgc ccttcatctt ttagcgcctg aatagaaagg ggaccaaaaa
    25261 cttcttccgg cgtggagaag cgggtcatca gatattcaaa cgcgcgggca ttctgaaagg
    25321 cgaattttaa gcgccgggcg atcaaacttt tggcaatacc tggcgggcca aggaggaaca
    25381 cactttcacc acttaatgcc gctaataaac acaagcggat ggcgtggcta cgttcataaa
    25441 gccccttttc caacgaactg ctcaggcggg aaattctttc cgctaataaa tgagggtgag
    25501 ccataatgaa gtggcgtcct ttcgtcaaaa gttctgcgta aattgcgagt atagacgttt
    25561 cttgctggtg gctaaaatag tctcaaaggg ggggtatttt tctttgagcc aggttaatgt
    25621 ggccgcattt aggagtacga ttttgccgtt aatcgtgcat actgtgcgct tttttgtggg
    25681 ccaagggact aagcacacat ttcatatttc aacgaaagac tagtctatga gcactgataa
    25741 taagcaatca ttgcccgcga ttaccctcgc ggcgattgga gttgtctacg gcgatattgg
    25801 taccagcccg ttatatacac ttcgtgaatg tttgtccggc cagtttggtt ttggcgttga
    25861 acgcgatgcc gtgtttggct ttttatcgct gatcttctgg ctgctaatct ttgtggtttc
    25921 cattaaatat ctcaccttcg tgatgcgggc agataacgcc ggtgaggggg ggatcctgac
    25981 gttgatgtcg cttgccgggc gtaatacgtc ggcgcgaacc acatcaatgc tggtgattat
    26041 ggggctaatc ggcggcagct ttttctatgg tgaagtcgtc ataacacccg ctatttcggt
    26101 gatgtcagcc attgaaggtc tggaaatcgt cgccccgcag ctggatacct ggatagtttc
    26161 cctctcaatt atcgttctca ctttattatt tatgattcaa aaacatggca cggctatggt
    26221 cggtaagctg tttgcgccga tcatgctgac ctggtttttg attctggcag gactggggtt
    26281 acgtagcatt attgctaacc cggaagtgct gcatgcgctg aatccaatgt gggcggtgca
    26341 tttcttcctt gaatacaaaa cggtttcttt tattgcatta ggggcagtgg tgttgtcgat
    26401 tacgggggtc gaggcgctgt atgctgatat ggggcacttt ggtaagttcc ctattcgcct
    26461 ggcgtggttc accgtcgtat taccttcctt gacccttaat tacttcggtc agggagcgct
    26521 gttgttaaag aacccggaag cgattaagaa cccgttcttc ctgttggcac cggactgggc
    26581 gctgatcccg ctgctgatca tcgccgcact ggcgacggta attgcctcgc aggcggttat
    26641 ctctggcgtc ttctcattga cgcgtcaggc ggtacgtctg ggatatttgt cgccgatgcg
    26701 cattattcac acctccgaaa tggagtcagg gcaaatctat attccgtttg tgaactggat
    26761 gctctatgtc gcggtcgtga ttgtgattgt cagctttgag cactccagca acctggcggc
    26821 ggcgtacggg attgcggtga ccggaaccat ggtgctgacg tctattctct cgactaccgt
    26881 ggcacgtcag aactggcact ggaataagta ttttgttgcg ctgatcctga ttgctttcct
    26941 ttgtgtcgat attccattgt tcaccgctaa cctcgataaa ctgctctccg gcggctggtt
    27001 gccattgagc ctcggtactg tgatgtttat cgtgatgacc acctggaaga gcgagcgttt
    27061 ccgcttgctg cggcggatgc atgaacatgg taactctctg gaagcgatga ttgcttcgct
    27121 ggagaaatca ccgcctgctc gcgtgcccgg gaccgcggtg tatatgtcgc gtgcaatcaa
    27181 cgtcattccc tttgcgctga tgcataacct taaacataac aaggtattgc atgagcgggt
    27241 gattctgtta actctgcgca ccgaagacgc tccatatgtc cataacgtcc gtcgggtaca
    27301 gattgaacaa ctgtcgccca ctttctggcg cgtggtggca agttatggtt ggcgagaaac
    27361 gccaaacgta gaagaagttt tccaccgctg cggtctggaa ggattaagtt gccggatgat
    27421 ggaaacctcc ttctttatgt cgcatgagtc gttgatcctc ggcaaacgcc cgtggtattt
    27481 gcgtctgcgc ggcaagctgt acttgctgct gcaacgtaat gcgctgcgtg caccagatca
    27541 atttgaaatc ccgccaaaca gggttatcga actgggtact caggtcgaaa tctaacgcca
    27601 gacgcctcct ttcttcataa gggggcgttt ttgttttcat ggttaatcac catgtaaaac
    27661 gtttcgaggt tgatcacatt tccgtaacgt cacgatggtt ttcccaactc agtcaggatt
    27721 aaactgtggg tcagcgaaac gtttcgctga tggagaaaaa aatgaaaaaa ggcaccgttc
    27781 ttaattctga tatttcatcg gtgatctccc gtctgggaca taccgatacg ctggtggtgt
    27841 gtgatgctgg tttacccatc cccaaaagta caacgcgtat cgatatggca ttaacccagg
    27901 gtgtaccttc ttttatgcag gtgctgggcg tcgtcacaaa tgaaatgcag gtcgaggcgg
    27961 ccattatcgc ggaagagatc aaacaccata atccgcaact ccacgaaacg ttgctcactc
    28021 accttgagca gctgcaaaaa caccagggaa ataccattga aattcgttac accacgcatg
    28081 aacaattcaa acaacaaacc gcagaaagtc aggcggtaat tcgcagcgga gaatgttctc
    28141 cgtatgcgaa tatcattctc tgtgctggcg tgacgttctg aggccgtcat ggaagcatta
    28201 cttcagctta aaggcatcga taaagccttc ccgggcgtaa aagccctctc gggcgcagcg
    28261 ttaaatgtct atccgggccg cgtgatggcg ctggtgggcg aaaacggcgc gggtaaatcc
    28321 accatgatga aagtgcttac tggcatctat actcgcgatg ccggtacgct tttatggctg
    28381 gggaaagaaa cgacatttac cgggccaaaa tcttcccagg aagccgggat tgggattatc
    28441 catcaggaac tgaacctgat cccgcagttg accattgccg aaaacatttt cctcggtcgt
    28501 gagtttgtta atcgctttgg caaaattgac tggaaaacca tgtatgccga agcggataaa
    28561 ttgctggcta aacttaacct gcgctttaaa agcgacaagc tggtgggcga tctttccatc
    28621 ggtgaccagc aaatggttga aatcgccaaa gtgctgagct ttgagtcgaa agtcatcatt
    28681 atggatgaac cgaccgatgc gctgaccgat accgaaaccg aatccctgtt ccgcgtcatc
    28741 cgcgagctga aatcgcaagg ccgcggtatt gtctatatct cccaccgcat gaaagaaatc
    28801 ttcgagattt gcgatgacgt taccgttttt cgtgatgggc aatttattgc tgagcgcgaa
    28861 gtggcatcac tgaccgaaga ttcgctgatt gagatgatgg tgggtcgcaa gctggaagat
    28921 caatatccgc acctggacaa agcgccggga gatatccgcc tgaaagtcga taatctctgc
    28981 ggacctggcg ttaacgatgt ctcttttact ttacgcaaag gcgaaattct tggcgtctct
    29041 ggtttgatgg gcgcaggtcg taccgaactg atgaaagtgc tctacggcgc actaccgcgc
    29101 accagcggtt acgtcaccct ggatgggcat gaagtcgtta cccgttcacc gcaggatggc
    29161 ctggcaaacg gcattgtgta tatctccgaa gaccgtaaac gtgacggttt agtgttgggc
    29221 atgtcagtaa aagagaacat gtcgctgaca gcgctgcgct acttcagccg cgctggcggc
    29281 agtttgaagc atgccgatga acagcaggct gtgagtgatt tcattcgtct gtttaatgtg
    29341 aaaactccgt cgatggaaca ggcaattggt ctgctttccg gtggcaatca gcaaaaagtg
    29401 gcgattgccc gcggtctgat gacacgcccc aaagtgttga tccttgatga acctacccgt
    29461 ggcgtagatg tcggcgcgaa aaaagagatc tatcaactga ttaaccagtt caaagccgat
    29521 ggcttgagca tcattctggt gtcatcggag atgccagaag tattaggcat gagcgatcgc
    29581 atcatcgtca tgcatgaagg gcatctcagc ggggaattta ctcgtgagca ggccacccag
    29641 gaagtgttaa tggctgccgc tgtgggcaag cttaatcgcg tgaatcagga gtaaaaaaat
    29701 gacaacccag actgtctctg gtcgccgtta tttcacgaaa gcgtggctga tggagcagaa
    29761 atcgcttatc gctctgctgg tgctgatcgc gattgtctcg acgttaagcc cgaacttttt
    29821 caccatcaat aatttattca atattctcca gcaaacctca gtgaacgcca ttatggcggt
    29881 cgggatgacg ctggtgatcc tgacgtcggg catcgactta tcggtaggtt ctctgttggc
    29941 gctgaccggc gcagttgctg catctatcgt cggcattgaa gtcaatgcgc tggtggctgt
    30001 cgctgctgct ctcgcgttag gtgccgcaat tggtgcggta accggggtga ttgtagcgaa
    30061 aggtcgcgtc caggcgttta tcgctacgct ggttatgatg cttttactgc gcggcgtgac
    30121 catggtttat accaacggta gcccagtgaa taccggcttt actgagaacg ccgatctgtt
    30181 tggctggttt ggtattggtc gtccgctggg cgtaccgacg ccagtctgga tcatggggat
    30241 tgtcttcctc gcggcctggt acatgctgca tcacacgcgt ctggggcgtt acatctacgc
    30301 gctgggcggc aacgaagcgg caacgcgtct ttctggtatc aacgtcaata aaatcaaaat
    30361 catcgtctat tctctttgtg gtctgctggc atcgctggcc gggatcattg aagtggcgcg
    30421 tctctcctcc gcacaaccca cggcggggac tggctatgag ctggatgcta ttgctgcggt
    30481 ggttctgggc ggtacgagtc tggcgggcgg aaaaggtcgc attgttggga cgttgatcgg
    30541 cgcattaatt cttggcttcc ttaataatgg attgaatttg ttaggtgttt cctcctatta
    30601 ccagatgatc gtcaaagcgg tggtgatttt gctggcggtg ctggtagaca acaaaaagca
    30661 gtaataacga ctacaggaca tcttgaatat gaacatgaaa aaactggcta ccctggtttc
    30721 cgctgttgcg ctaagcgcca ccgtcagtgc gaatgcgatg gcaaaagaca ccatcgcgct
    30781 ggtggtctcc acgcttaaca acccgttctt tgtatcgctg aaagatggcg cgcagaaaga
    30841 ggcggataaa cttggctata acctggtggt gctggactcc cagaacaacc cggcgaaaga
    30901 gctggcgaac gtgcaggact taaccgttcg cggcacaaaa attctgctga ttaacccgac
    30961 cgactccgac gcagtgggta atgctgtgaa gatggctaac caggcgaaca tcccggttat
    31021 cactcttgac cgccaggcaa cgaaaggtga agtggtgagc cacattgctt ctgataacgt
    31081 actgggcggc aaaatcgctg gtgattacat cgcgaagaaa gcgggtgaag gtgccaaagt
    31141 tatcgagctg caaggcattg ctggtacatc cgcagcccgt gaacgtggcg aaggcttcca
    31201 gcaggccgtt gctgctcaca agtttaatgt tcttgccagc cagccagcag attttgatcg
    31261 cactaaaggt ttgaacgtaa tgcagaacct gttgaccgct catccggatg ttcaggctat
    31321 attcgcgcag aatgatgaaa tggcgctggg cgcgctgcgc gcactgcaaa ctgccggtaa
    31381 atcggatgtg atggtcgtcg gatttgacgg tacaccggat ggcgaaaaag cggtgaatga
    31441 tggcaaacta gcagcgacta tcgctcagct acccgatcag attggcgcga aaggcgtcga
    31501 aaccgcagat aaagtgctga aaggcgagaa agttcaggct aagtatccgg ttgatctgaa
    31561 actggttgtt aagcagtagt tttaatcagg ttgtatgacc tgatggtgac ataaatacgt
    31621 catcgacaga tgaacgtgta atataaagaa aagcagggca cgcgccaccc taacacggtg
    31681 gcgcatttta tggacatccc gaatatgcaa aacgcaggca gcctcgttgt tcttggcagc
    31741 attaatgctg accacattct taatcttcaa tcttttccta ctccaggcga aaccgtaacc
    31801 ggtaaccact atcaggttgc atttggcggc aaaggcgcga atcaggctgt ggctgctggg
    31861 cgtagcggtg cgaatatcgc gtttattgcc tgtacgggtg atgacagcat tggtgagagc
    31921 gttcgccagc agctcgccac tgataacatt gatattactc cggtcagcgt gatcaaaggc
    31981 gaatcaacag gtgtggcgct gatttttgtt aatggcgaag gtgagaatgt catcggtatt
    32041 catgccggcg ctaatgctgc cctttccccg gcgctggtgg aagcgcaacg tgagcgtatt
    32101 gccaacgcgt cagcattatt aatgcagctg gaatcaccac tcgaaagtgt gatggcagcg
    32161 gcgaaaatcg cccatcaaaa taagactatc gttgcgctta acccggctcc ggctcgcgaa
    32221 cttcctgacg aactgctggc gctggtggac attattacgc caaacgaaac ggaagcagaa
    32281 aagctcaccg gtattcgtgt tgaaaatgat gaagatgcag cgaaggcggc gcaggtactg
    32341 catgaaaaag gtatccgtac tgtactgatt actttaggaa gtcgtggtgt atgggctagc
    32401 gtgaatggtg aaggtcagcg cgttcctgga ttccgggtgc aggctgtcga taccattgct
    32461 gccggagata cctttaacgg tgcgttaatc acggcattgc tggaagaaaa accattgcca
    32521 gaggcgattc gttttgccca tgctgccgct gcgattgccg taacacgtaa aggcgcacaa
    32581 ccttccgtac cgtggcgtga agagatcgac gcatttttag acaggcagag gtgacgcttg
    32641 gctacaatga aagatgttgc ccgcctggcg ggcgtttcta cctcaacagt ttctcacgtt
    32701 atcaataaag atcgcttcgt cagtgaagcg attaccgcca aagttgaagc ggcgattaaa
    32761 gaactcaatt acgcgccatc agctctggcg cgtagcctca aactcaatca aacacatacc
    32821 attggcatgt tgatcactgc cagtaccaat cctttctatt cagaactggt gcgtggcgtt
    32881 gaacgcagct gcttcgaacg cggttatagt ctcgtccttt gcaataccga aggcgatgaa
    32941 cagcggatga atcgcaatct ggaaacgctg atgcaaaaac gcgttgatgg cttgctgtta
    33001 ctgtgcaccg aaacgcatca accttcgcgt gaaatcatgc aacgttatcc gacagtgcct
    33061 actgtgatga tggactgggc tccgttcgat ggcgacagcg atcttattca ggataactcg
    33121 ttgctgggcg gagacttagc aacgcaatat ctgatcgata aaggtcatac ccgtatcgcc
    33181 tgtattaccg gcccgctgga taaaactccg gcgcgcctgc ggttggaagg ttatcgggcg
    33241 gcgatgaaac gtgcgggtct caacattcct gatggctatg aagtcactgg tgattttgaa
    33301 tttaacggcg ggtttgacgc tatgcgccaa ctgctatcac atccgctgcg tcctcaggcc
    33361 gtctttaccg gaaatgacgc tatggctgtt ggcgtttacc aggcgttata tcaggcagag
    33421 ttacaggttc cgcaggatat cgcggtgatt ggctatgacg atatcgaact ggcaagcttt
    33481 atgacgccac cattaaccac tatccaccaa ccgaaagatg aactggggga gctggcgatt
    33541 gatgtactca tccatcggat aacccagccg acccttcagc aacaacgatt acaacttact
    33601 ccgattctga tggaacgcgg ttcggcttag atttacgctg tcttttgatc aaattattac
    33661 catcggttgt tttcagaagc atgaacattg ctgctgaagc aacagtaata atgcccattg
    33721 tgataaacgt atagtggaat tgttcgacag tcgttgtgcc ttccattcct tcataaacgc
    33781 gaaggacggc cgcacttaca gcaacgccta aactaatcga cagttgctgc gtgaccgcca
    33841 gaacactgtt accgctgctg gcattgtcat cggtcagatc ggcaagtgtg atggtattca
    33901 tcgcggtaaa ctgcgtcgac atagccatcc ctaatataaa caacggcaag atcagcatcc
    33961 atatagccat tgctggtgat tgcaaagaga actgagcgat cattagccca ataatcaccg
    34021 tgatccccac taacgtatgg cgatagccca gacgacgtaa gacttgggta accatcgatt
    34081 ttgcaataat ggaacctaac gctgtcggtg ccatcataca gccagccata aacgcctgat
    34141 aaccaaatcc tacctgtaac atcaatggca taaggaacgg tacacagccg gtccccagac
    34201 gggttgcaat attgcctacg ataccgatcg agaaagtgcg ggttttaaat aaatctaatg
    34261 aaattaatgg gtttggcgtg cgtcgtgcat ggagaatata gagaagcagt aacccgatgc
    34321 tggtgacaat taccgtcaag gcaatccagc tggcgacaat cttttccccg aatagctcta
    34381 ttccgcttga gaagagaaca aggctgaggc caaacagcaa aaagccagtg atatcgaatc
    34441 tgcgtcgtgc ggtggtgaaa ttgggcatat gtttgcgcgc gtaaagaagg cccgcaatac
    34501 ctatggggat attgattaaa aatatccagt gccaggttgc ccaggtgacc agcacgccgc
    34561 caagaacggg gcctaaaatt ggccccacca gacccggcat ggcgacaaaa ttcaatactg
    34621 gaagaagttc attacgagga taagcgcgca gtaaggccag ccgagcaaca ggcatcatca
    34681 ttgcgccgcc tatcccctga ataacccgga agacaaccag ctgtggtagc gaattagaaa
    34741 gtgcgcaggc cagagaaccc aatgtgaaca gactcacggc aagggtaaaa atgcgacgcg
    34801 taccgaagcg atcggctagc catccgctta ccggaataag catcgccacc gtcagcgtat
    34861 aactgatgat ggctgattgc atcgcgagag gagaacgatt aaggctatga gcgattgcgg
    34921 gtaaggcggt attaagaata gtggcatcaa gtgcctgcat gaagaaggcc atcgccgcga
    34981 tccacggcaa acccgccata ctgcgcttct ttttatcgct cattcaatgt cctgttatcg
    35041 ggttatcact tatcaggtga gcgtagcagc gcctgacaag ctttaaatgc cgcgtcgcca
    35101 tcgctttgga taatcgcatc gacaatcgcc tgatgcagat ccagctttat cactgtgtcg
    35161 ctggtaattg acgtgaagta agtgtgataa accgaatgga atagcgaggc gaatgaggtc
    35221 aaaaacggat tggcgctcat ttcatagata tgctcatgcc aggccatatc gacttcgatc
    35281 cagcgttcac ggcgaaagtt ctcttttaat gccgccattt cggccattaa cgtattgaga
    35341 tgcgctttct gttccgcggt gccaaccgtt gctgccagta ggcaggcttg cggctccaga
    35401 cagatacgca taaccagaaa gtgatcgatg acctgatgaa agttctcttc tgtcatccac
    35461 caggtaagca attcctgatc aagaaaattc cagttcgatt gtggcatgac ccgagtacca
    35521 attcgcggtc gcggtaaaac catccctttt gccgttaacg ttttgaccgc ttcgcgtacc
    35581 gctgtacgac tcactccaaa ttgctcgccc agctcaatct caccgggcaa aatggtgccg
    35641 ggttcatatt caccttttaa gatccgttgc gccagcttct cagccagaac atacgaaagg
    35701 tttttctgtg cagctaactg ttgtgcgctt aaaggcatta cttatcttcc tttttctttt
    35761 tattcctcct tagtatgcca ccaggaagtg tgattacggt tgcaaaaacg gcaaattgct
    35821 tgttttatgg cacattaacg gggcttttgc tgaaaaaatg cgcggtcaga aaattatttt
    35881 aaatttcctc ttgtcaggcc ggaataactc c
//
LOCUS       DAPOAV010000044        35897 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.044, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000044 DAPOAV010000000
VERSION     DAPOAV010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 35897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35897
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.044"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..89)
                     /locus_tag="RN951_002430"
     CDS             complement(<1..89)
                     /locus_tag="RN951_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2170 domain-containing protein"
                     /protein_id="HDX2527420.1"
                     /translation="MTWNPLALATALQTVPEQNIDVTNSENAL"
     gene            complement(216..947)
                     /gene="rlmB"
                     /locus_tag="RN951_002431"
     CDS             complement(216..947)
                     /gene="rlmB"
                     /locus_tag="RN951_002431"
                     /EC_number="2.1.1.185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HDX2527421.1"
                     /translation="MSEMIYGIHAVQALLERAPERFQEVFILKGREDKRLLPLIHALE
                     SQGVVIQLANRQYLDEKSDGAVHQGIIARVKPGRQYQENDLPDLIASLDQPFLLILDG
                     VTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAESVPLIRVTNLART
                     MRMLQEENIWIVGTAGEADHTLYQSKMTGRLALVMGAEGEGMRRLTREHCDELISIPM
                     AGSVSSLNVSVATGICLFEAVRQRS"
     gene            complement(1127..3568)
                     /gene="rnr"
                     /locus_tag="RN951_002432"
     CDS             complement(1127..3568)
                     /gene="rnr"
                     /locus_tag="RN951_002432"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418600.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HDX2527422.1"
                     /translation="MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASRDELAVEL
                     HIEGEEQLEGLRRRLRAMERDGQLVFTRRQCYALPERLDLVKGTVIGHRDGYGFLRVE
                     GRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTEA
                     GVGFVVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNM
                     GTGMAVDIALRTHEIPYIWPQAVEQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDGEDA
                     RDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPSTPLDREARNRGTSVYFPSQVIPMLP
                     EVLSNGLCSLNPQVDRLCMVCEMTVSSKGRLTGYKFYEAVMSSHARLTYTKVWHILQG
                     DQDLREQYAPLVKHLEELHNLYKVLDKAREERGGISFESEEAKFIFNAERRIERIEQT
                     QRNDAHKLIEECMILANISAARFVEKAKEPALFRIHDKPSTEAITSFRSVLAELGLEL
                     PGGNKPEPRDYAELLESVADRPDAEMLQTMLLRSMKQAIYDPENRGHFGLALQSYAHF
                     TSPIRRYPDLTLHRAIKYLLAKEQGHQGNTTETGGYHYSMEEMLQLGQHCSMAERRAD
                     EATRDVADWLKCDFMLDQVGNVFKGVISSVTGFGFFVRLDDLFIDGLVHVSSLDNDYY
                     RFDQVGQRLMGESSGQTYRLGDRVEVRVEAVNMDERKIDFSLISSERAPRNVGKTARE
                     KAKKGDAGKKGGKRRQVGKKVNFEPDSAFRGEKKTKPKAAKKDARKAKKPSAKTQKIA
                     AATKAKRAAKKKVAE"
     gene            complement(3607..4032)
                     /gene="nsrR"
                     /locus_tag="RN951_002433"
     CDS             complement(3607..4032)
                     /gene="nsrR"
                     /locus_tag="RN951_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide-sensing transcriptional repressor
                     NsrR"
                     /protein_id="HDX2527423.1"
                     /translation="MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVK
                     IINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVVRELEPLSLVNCSSEFCHITPAC
                     RLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE"
     gene            complement(4237..5535)
                     /gene="purA"
                     /locus_tag="RN951_002434"
     CDS             complement(4237..5535)
                     /gene="purA"
                     /locus_tag="RN951_002434"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HDX2527424.1"
                     /translation="MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTL
                     VINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSE
                     ACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAE
                     KLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDF
                     VMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGA
                     GPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLD
                     VLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGL
                     PQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA"
     gene            complement(5639..5836)
                     /locus_tag="RN951_002435"
     CDS             complement(5639..5836)
                     /locus_tag="RN951_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2065 domain-containing protein"
                     /protein_id="HDX2527425.1"
                     /translation="MNSTIWLALALVLVLEGLGPMLYPKAWKKMISAMTNLPDNILRR
                     FGGGLVVAGVVVYYMLRKTIG"
     gene            complement(5918..6922)
                     /gene="hflC"
                     /locus_tag="RN951_002436"
     CDS             complement(5918..6922)
                     /gene="hflC"
                     /locus_tag="RN951_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease modulator HflC"
                     /protein_id="HDX2527426.1"
                     /translation="MRKSVIAIIIIVLVVLYMSVFVVKEGERGITLRFGKVLRDDDNK
                     PLVYEPGLHFKIPFIETVKMLDARIQTMDNQADRFVTKEKKDLIVDSYIKWRISDFSR
                     YYLATGGGDISQAEVLLKRKFSDRLRSEIGRLDVKDIVTDSRGRLTLEVRDALNSGSA
                     GTEDEVTTPAADNAIAEAAERVTAETKGKVPVINPNSMAALGIEVVDVRIKQINLPTE
                     VSEAIYNRMRAEREAVARRHRSQGQEEAEKLRATADYEVTRTLAEAERQGRIMRGEGD
                     AEAAKLFADAFSKDPDFYAFIRSLRAYENSFSGNQDVMVMSPDSDFFRYMKTPTSATR
                     "
     gene            complement(6925..8184)
                     /gene="hflK"
                     /locus_tag="RN951_002437"
     CDS             complement(6925..8184)
                     /gene="hflK"
                     /locus_tag="RN951_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease activity modulator HflK"
                     /protein_id="HDX2527427.1"
                     /translation="MAWNQPGNNGQDRDPWGSSKPGGNSEGNGNKGGRDQGPPDLDDI
                     FRKLSKKLGGLGGGKGTGSGGGSSSQGPRPQLGGRVVTIAAAAIVIIWAASGFYTIKE
                     AERGVVTRFGKFSHLVEPGLNWKPTFIDEVKPVNVEAVRELAASGVMLTSDENVVRVE
                     MNVQYRVTNPEKYLYSVTSPDDSLRQATDSALRGVIGKYTMDRILTEGRTVIRSDTQR
                     ELEETIRPYDMGITLLDVNFQAARPPEEVKAAFDDAIAARENEQQYIREAEAYTNEVQ
                     PRANGQAQRILEEARAYKAQTILEAQGEVARFAKLLPEYKAAPEITRERLYIETMEKV
                     LGNTRKVLVNDKGGNLMVLPLDQMLKGGNAPAAKSDNGASNLLRLPPASSSTTSGASN
                     TSSTSQGDIMDQRRANAQRNDYQRQGE"
     gene            complement(8270..9550)
                     /gene="hflX"
                     /locus_tag="RN951_002438"
     CDS             complement(8270..9550)
                     /gene="hflX"
                     /locus_tag="RN951_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDX2527428.1"
                     /translation="MFDRYDAGEQAVLVHIYFTQDKDMEDLQEFESLVSSAGVEALQV
                     ITGSRKAPNPKYFVGEGKAVEIAEAVKATGASVVLFDHALSPAQERNLERLCECRVID
                     RTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQL
                     ETDRRLLRNRIVQIQSRLERVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNRIT
                     EARVYAADQLFATLDPTLRRIDVADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQ
                     ATLLLHVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLEDFEPRIDRDEE
                     NKPIRVWLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKE
                     WMEEDGSVSLQVRMPIVDWRRLCKQEPALIDYLI"
     gene            complement(9626..9934)
                     /gene="hfq"
                     /locus_tag="RN951_002439"
     CDS             complement(9626..9934)
                     /gene="hfq"
                     /locus_tag="RN951_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HDX2527429.1"
                     /translation="MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVI
                     LLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTSSNYHHGSSAQNTSAQQDSEETE
                     "
     gene            complement(10020..10970)
                     /gene="miaA"
                     /locus_tag="RN951_002440"
     CDS             complement(10020..10970)
                     /gene="miaA"
                     /locus_tag="RN951_002440"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HDX2527430.1"
                     /translation="MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSA
                     LIYKGMDIGTAKPNAEELLAAPHRLLDIRDPSQAYSAADFRRDALAEMADITAAGRIP
                     LLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEVDPVAAARI
                     HPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRF
                     HQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYLEGEISYDEMVYRGVCATR
                     QLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG"
     gene            complement(10963..12810)
                     /gene="mutL"
                     /locus_tag="RN951_002441"
     CDS             complement(10963..12810)
                     /gene="mutL"
                     /locus_tag="RN951_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HDX2527431.1"
                     /translation="MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDI
                     DIERGGAKLIRIRDNGCGIKKDELALALARHATSKIASLDDLEAIISLGFRGEALASI
                     SSVSRLTLTSRTAEQQEAWQAYAEGRDMNVTVKPAAHPVGTTLEVLDLFYNTPARRKF
                     LRTEKTEFNHIDEIIRRIALARFDVTINLSHNGKIVRQYRAVPEGGQKERRLGAICGT
                     AFLEQALAIEWQHGDLTLRGWVADPNHTTPALAEIQYCYVNGRMMRDRLINHAIRQAC
                     EDKLGADQQPAFVLYLEIDPHQVDVNVHPAKHEVRFHQSRLVHDFIYQGVLSVLQQQL
                     ETPLPLDDEPQPAPRSIPENRVAAGRNHFAEPAAREPVAPRYTPAPASGSRPAAPWPN
                     AQPGYQKQQGEVYRQLLQTPAPMQKLKAPEPQEPALAANSQSFGRVLTIVHSDCALLE
                     RDGNISLLSLPVAERWLRQAQLTPGEAPVCAQPLLIPLRLKVSAEEKSALEKAQSALA
                     ELGIDFQSDAQHVTIRAVPLPLRQQNLQILIPELIGYLAKQSVFEPGNIAQWIARNLM
                     SEHAQWSMAQAITLLADVERLCPQLVKTPPGGLLQSVDLHPAIKALKDE"
     gene            complement(12820..14157)
                     /gene="amiB"
                     /locus_tag="RN951_002442"
     CDS             complement(12820..14157)
                     /gene="amiB"
                     /locus_tag="RN951_002442"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiB"
                     /protein_id="HDX2527432.1"
                     /translation="MMYRIRNWLVATLLLLCTPVGAATLSDIQVSNGNQQARITLSFI
                     GDPDYAFSHQSKRTVALDIKQTGVIQGLPLLFSGNNLVKAIRSGTPKDAQTLRLVVDL
                     TENGKTEAVKRQNGSNYTVVFTINADVPPPPPPPPVVAKRVETPAVVAPRVSEPARNP
                     FKTESNRTTGVISSNTVTRPAARATANTGDKIIIAIDAGHGGQDPGAIGPGGTREKNV
                     TIAIARKLRTLLNDDPMFKGVLTRDGDYFISVMGRSDVARKQNANFLVSIHADAAPNR
                     SATGASVWVLSNRRANSEMASWLEQHEKQSELLGGAGDVLANSQSDPYLSQAVLDLQF
                     GHSQRVGYDVATSMISQLQRIGEIHKRRPEHASLGVLRSPDIPSVLVETGFISNNSEE
                     RLLASDDYQQQLAEAIYKGLRNYFLAHPMQSAPQGATAQTASTVTTPDRTLPN"
     gene            complement(14176..14637)
                     /gene="tsaE"
                     /locus_tag="RN951_002443"
     CDS             complement(14176..14637)
                     /gene="tsaE"
                     /locus_tag="RN951_002443"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HDX2527433.1"
                     /translation="MMNRVIPLPDEQATLDLGERVAKACDGATVIYLYGDLGAGKTTF
                     SRGFLQALGHQGNVKSPTYTLVEPYTLDNLMVYHFDLYRLADPEELEFMGIRDYFAND
                     AICLVEWPQQGTGVLPDPDVEIHIDYQAQGREARVSAVSSAGELLLARLAG"
     gene            complement(14609..16156)
                     /gene="nnr"
                     /locus_tag="RN951_002444"
     CDS             complement(14609..16156)
                     /gene="nnr"
                     /locus_tag="RN951_002444"
                     /EC_number="4.2.1.136"
                     /EC_number="5.1.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HDX2527434.1"
                     /translation="MTDHTMKKNPVSIPHTVWYADDIRRGEREAADVLGLTLYELMLR
                     AGEAAFQVCRSAYPDARHWLVLCGHGNNGGDGYVVARLAKAVGIEVTLLAQESDKPLP
                     EEAALAREAWLNAGGEIHASNIVWPESVDLIVDALLGTGLRQAPRESISQLIDHANSH
                     PAPIVAVDIPSGLLAETGATPGAVINADHTITFIALKPGLLTGKARDVTGQLHFDSLG
                     LDSWLAGQETKIQRFSAEQLSHWLKPRRPTSHKGDHGRLVIIGGDHGTAGAIRMTGEA
                     ALRAGAGLVRVLTRSENIAPLLTARPELMVHELTMDSLTESLEWADVVVIGPGLGQQE
                     WGKKALQKVENFRKPMLWDADALNLLAINPDKRHNRVITPHPGEAARLLGCSVAEIES
                     DRLHCAKRLVQRYGGVAVLKGAGTVVAAHPDALGIIDAGNAGMASGGMGDVLSGIIGA
                     LLGQKLSPYDAACAGCVAHGAAADVLAARFGTRGMLATDLFSTLQRIVNPEVTDKNHD
                     ESSNSAP"
     gene            16155..17294
                     /gene="queG"
                     /locus_tag="RN951_002445"
     CDS             16155..17294
                     /gene="queG"
                     /locus_tag="RN951_002445"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HDX2527435.1"
                     /translation="MSEPLDLNQLAQKIKQWGLELGFQQVGITDTDLSESEPKLQAWL
                     DKQYHGEMDWMARHGMLRARPHELLPGTLRVISVRMNYLPANAAFASTLKNPKLGYVS
                     RYALGRDYHKLLRNRLKKLGEMIQQHCVSLNFRPFVDSAPILERPLAEKAGLGWTGKH
                     SLILNREAGSFFFLGELLVDIPLPVDQPVEEGCGKCVACMTICPTGAIVEPYTVDARR
                     CISYLTIELEGAIPEELRPLMGNRIYGCDDCQLICPWNRYSQLTTEEDFSPRKPLHAP
                     ELIELFAWSEEKFLKVTEGSAIRRIGHLRWLRNIAVALGNAPWDETILTALESRKGEH
                     PLLDEHIAWAIAQQIERRNACIVEVQLPKKQRLVRVIEKGLPRDA"
     gene            complement(17277..17330)
                     /locus_tag="RN951_002446"
     CDS             complement(17277..17330)
                     /locus_tag="RN951_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527436.1"
                     /translation="MRFYFYSQAVDESGVTR"
     gene            complement(17564..17639)
                     /locus_tag="RN951_002447"
     tRNA            complement(17564..17639)
                     /locus_tag="RN951_002447"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17604..17606),aa:Gly,seq:gcc)
     gene            complement(17675..17750)
                     /locus_tag="RN951_002448"
     tRNA            complement(17675..17750)
                     /locus_tag="RN951_002448"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17715..17717),aa:Gly,seq:gcc)
     gene            complement(17787..17862)
                     /locus_tag="RN951_002449"
     tRNA            complement(17787..17862)
                     /locus_tag="RN951_002449"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17827..17829),aa:Gly,seq:gcc)
     gene            complement(18073..18618)
                     /gene="orn"
                     /locus_tag="RN951_002450"
     CDS             complement(18073..18618)
                     /gene="orn"
                     /locus_tag="RN951_002450"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoribonuclease"
                     /protein_id="HDX2527437.1"
                     /translation="MSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGP
                     TIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAGKS
                     PICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQA
                     MDDIRESVAELAYYREHFIKL"
     gene            18713..19765
                     /gene="rsgA"
                     /locus_tag="RN951_002451"
     CDS             18713..19765
                     /gene="rsgA"
                     /locus_tag="RN951_002451"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418585.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small ribosomal subunit biogenesis GTPase RsgA"
                     /protein_id="HDX2527438.1"
                     /translation="MSKNKLSKGQQRRVNANHQRRLKTSKEKPDYDDNLFGEPDEGIV
                     ISRFGMHADVESADGDVHRCNIRRTIRSLVTGDRVVWRPGKPAAEGVNVKGIVEAVHE
                     RTSVLTRPDFYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVACETLQIEPIIVLN
                     KIDLLDDEGMAFVNEQMDIYRNIGYRVLMVSSHTQDGLKPLEEALTGRISIFAGQSGV
                     GKSSLLNALLGLQKEILTNDISDNSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLW
                     HLEPEQITQGFVEFHDYLGLCKYRDCKHDTDPGCAIREAVEEGKIAETRFENYHRILE
                     SMAQVKTRKNFSDTDD"
     gene            19862..20830
                     /gene="psd"
                     /locus_tag="RN951_002452"
     CDS             19862..20830
                     /gene="psd"
                     /locus_tag="RN951_002452"
                     /EC_number="4.1.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313166.1"
                     /note="Phosphatidylserine decarboxylase is synthesized as
                     a single chain precursor. Generation of the pyruvoyl
                     active site from a Ser is coupled to cleavage of a Gly-Ser
                     bond between the larger (beta) and smaller (alpha chains).
                     It is an integral membrane protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylserine decarboxylase"
                     /protein_id="HDX2527439.1"
                     /translation="MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKY
                     YKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEED
                     KILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYV
                     PGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTIT
                     PPREGIIKRWTWPAGENDGSVALLKGQEMGRFKLGSTVINLFAPGKVNLVEQLESLSV
                     TKIGQPLAVSTETFVTPDAEPAPLPAEEIEAEHDASPLVDDKKDQV"
     gene            20852..24175
                     /gene="mscM"
                     /locus_tag="RN951_002453"
     CDS             20852..24175
                     /gene="mscM"
                     /locus_tag="RN951_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="miniconductance mechanosensitive channel MscM"
                     /protein_id="HDX2527440.1"
                     /translation="MRLIITFLMAWCLSWGAYAATAPDSKQITQELEQAKAAKPAQPE
                     VVEALQSALNALEERKGSLERIKQYQQVIDNYPKLSATLRAQLNNMRDEPRSVSPGMS
                     TDALNQEILQVSSQLLDKSRQAQQEQERAREIADSLNQLPQQQTDARRQLNEIERRLG
                     TLTGNTPLNQAQNFALQSDSARLKALVDELELAQLSANNRQELARLRSELAEKESQQL
                     DAYLQALRNQLNSQRQLEAERALESTELLAENSADLPKDIVAQFKINRELSAALNQQA
                     QRMDLVASQQRQAASQTLQVRQALNTLREQSQWLGSSNLLGEALRAQVARLPEMPKPQ
                     QLDTEMAQLRVQRLRYEDLLNKQPLLRQIHQADGQPLTAEQNRILEAQLRTQRELLNS
                     LLQGGDTLLLELTKLKVSNGQLEDALKEVNEATHRYLFWTSDVRPMTIAWPLEIAQDL
                     RRLISLDTFSQLGKASVMMLTSKETILPLFGALILVGCSIYSRRYFTRFLERSAAKVG
                     KVTQDHFWLTLRTLFWSILVASPLPVLWMTLGYGLREAWPYPLAVAIGDGVTATVPLL
                     WVVMICATFARPNGLFIAHFGWPRERVSRGMRYYLMSIGLIVPLIMALMMFDNLDDRE
                     FSGSLGRLCFILICGALAVVTLSLKKAGIPLYLNKEGSGDNITNHMLWNMMIGAPLVA
                     ILASAVGYLATAQALLARLETSVAIWFLLLVVYHVIRRWMLIQRRRLAFDRAKHRRAE
                     MLAQRARGEEEAHHHSSPEGAIEVDESEVDLDAISAQSLRLVRSILMLIALLSVIVLW
                     SEIHSAFGFLENISLWDVTSTVQGVESLEPITLGAVLIAILVFIITTQLVRNLPALLE
                     LAILQHLDLTPGTGYAITTITKYLLMLIGGLVGFSMIGIEWSKLQWLVAALGVGLGFG
                     LQEIFANFISGLIILFEKPIRIGDTVTIRDLTGSVTKINTRATTISDWDRKEIIVPNK
                     AFITEQFINWSLSDSVTRVVLTIPAPADANSEEVTEILLTAARRCSLVIDNPAPEVFL
                     VDLQQGIQIFELRIYAAEMGHRMPLRHEIHQLILAGFHAHGIDMPFPPFQMRLESLNG
                     KQTGRTLTSAGKGRQAGSL"
     gene            complement(24204..24518)
                     /locus_tag="RN951_002454"
     CDS             complement(24204..24518)
                     /locus_tag="RN951_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjeO family protein"
                     /protein_id="HDX2527441.1"
                     /translation="MSARMFVLCCIWFIVAFLWITITSALDKEWMIDGRGINNVCDVL
                     MYLEEDDTRDVGVIMTLPLFFPFLWFALWRKKRGWFMYATALAIFGYWLWQFFLRYQF
                     CL"
     gene            complement(24515..24829)
                     /locus_tag="RN951_002455"
     CDS             complement(24515..24829)
                     /locus_tag="RN951_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527442.1"
                     /translation="MDDTSRDPAITEDEIRALQFSAGDVAEIEQTILSFVDACHTRKV
                     AMVVGSTINTLKDRDGKRWGNLPDIYCAYLIRCLVFRGELVGYGDLFRMRYSEIKRPV
                     TL"
     gene            complement(24881..26383)
                     /gene="yjeM"
                     /locus_tag="RN951_002456"
     CDS             complement(24881..26383)
                     /gene="yjeM"
                     /locus_tag="RN951_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418580.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/gamma-aminobutyrate family transporter
                     YjeM"
                     /protein_id="HDX2527443.1"
                     /translation="MPHTIKKMSLIGLILMIFTSVFGFANSPSAYYLMGYSAIPFYIF
                     SALLFFIPFALMMAEMGAAYRKEEGGIYSWMNNSVGPRFAFIGTFMWFSSYIIWMVST
                     SAKVWVPFSTFLYGSDMTQHWRIAGLEPTQVVGLLAVAWMILVTVVASKGINKIARIT
                     AVGGIAVMCLNLVLLLVSITILLLNGGHFAQDINFLASPNPGYQSGLAMLSFVVFAIF
                     AYGGIEAVGGLVDKTENPEKNFAKGIVFAAIVISIGYSLAIFLWGVSTNWQQVLSNGS
                     VNLGNITYVLMKSLGMTLGNALHLSPEASLSLGVWFARITGLSMFLAYTGAFFTLCYS
                     PLKAIIQGTPKALWPEPMTRLNAMGMPSIAMWMQCGLVTVFILLVSFGGGTASAFFNK
                     LTLMANVSMTLPYLFLALAFPFFKARQDLDRPFVIFKTHLSAMIATVVVVLVVTFANV
                     FTIIQPVVEAGDWDSTLWMIGGPVFFSLLAMAIYQNYCSRVAKNPQWAVE"
     gene            complement(26602..27579)
                     /gene="epmA"
                     /locus_tag="RN951_002457"
     CDS             complement(26602..27579)
                     /gene="epmA"
                     /locus_tag="RN951_002457"
                     /EC_number="6.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P--(R)-beta-lysine ligase"
                     /protein_id="HDX2527444.1"
                     /translation="MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMS
                     QATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNE
                     EMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEID
                     PLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNFGKEKPTFVYHFPAS
                     QASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQ
                     HPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA"
     gene            27904..29712
                     /gene="frdA"
                     /locus_tag="RN951_002458"
     CDS             27904..29712
                     /gene="frdA"
                     /locus_tag="RN951_002458"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase (quinol) flavoprotein
                     subunit"
                     /protein_id="HDX2527445.1"
                     /translation="MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRS
                     HTVAAEGGSAAVAQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGC
                     PWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLD
                     ILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMAL
                     SHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLG
                     EPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICE
                     LAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRL
                     GSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWA
                     KIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIE
                     LGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEY
                     SDVKITTLPPAKRVYGGEADAADKAEAANKKEKANG"
     gene            29705..30439
                     /gene="frdB"
                     /locus_tag="RN951_002459"
     CDS             29705..30439
                     /gene="frdB"
                     /locus_tag="RN951_002459"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase iron-sulfur protein"
                     /protein_id="HDX2527446.1"
                     /translation="MAEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYI
                     KDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERD
                     LVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACP
                     QFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKH
                     VDPAAAIQQGKVESSKDFLIATLKPR"
     gene            30450..30845
                     /gene="frdC"
                     /locus_tag="RN951_002460"
     CDS             30450..30845
                     /gene="frdC"
                     /locus_tag="RN951_002460"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdC"
                     /protein_id="HDX2527447.1"
                     /translation="MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELI
                     FGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDE
                     KMGPEPIIKSLWAVTVVATIVILFVALYW"
     gene            30856..31215
                     /gene="frdD"
                     /locus_tag="RN951_002461"
     CDS             30856..31215
                     /gene="frdD"
                     /locus_tag="RN951_002461"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdD"
                     /protein_id="HDX2527448.1"
                     /translation="MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGL
                     FPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFY
                     GLAAILTVVTLIGVVTI"
     gene            31278..32411
                     /locus_tag="RN951_002462"
     CDS             31278..32411
                     /locus_tag="RN951_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaEC family class C beta-lactamase"
                     /protein_id="HDX2527449.1"
                     /translation="MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGM
                     AVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLS
                     DPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAP
                     GTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWG
                     YREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYW
                     QTGDMYQGLGWEMLDWPVNPDSIINGSDNKIALAARPVKAITPPTPAVRASWVHKTGA
                     TGGFGSYVAFIPEKELGIVMLANKNYPNPARVDAAWQILNALQ"
     gene            32500..33033
                     /gene="blc"
                     /locus_tag="RN951_002463"
     CDS             32500..33033
                     /gene="blc"
                     /locus_tag="RN951_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin Blc"
                     /protein_id="HDX2527450.1"
                     /translation="MRLLPLVAAATAAFLVVACSSPTPPRGVTVVNNFDAKRYLGTWY
                     EIARFDHRFERGLEKVTATYSLRDDGGLNVINKGYNPDRGMWQQSEGKAYFTGAPTRA
                     ALKVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEVKQEMLAVAT
                     REGFDVSKFIWVQQPGS"
     gene            complement(33030..33347)
                     /gene="sugE"
                     /locus_tag="RN951_002464"
     CDS             complement(33030..33347)
                     /gene="sugE"
                     /locus_tag="RN951_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418572.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HDX2527451.1"
                     /translation="MSWIILVIAGLLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSMA
                     LLAWAMKSLPVGTAYAVWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKL
                     STH"
     gene            complement(33523..33669)
                     /gene="ecnB"
                     /locus_tag="RN951_002465"
     CDS             complement(33523..33669)
                     /gene="ecnB"
                     /locus_tag="RN951_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein toxin entericidin B"
                     /protein_id="HDX2527452.1"
                     /translation="MVKKTIAAIFSVLVLSTVLTACNTTRGVGEDISDGGNAISGAAT
                     KAQQ"
     gene            complement(33780..33905)
                     /gene="ecnA"
                     /locus_tag="RN951_002466"
     CDS             complement(33780..33905)
                     /gene="ecnA"
                     /locus_tag="RN951_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein antitoxin entericidin A"
                     /protein_id="HDX2527453.1"
                     /translation="MMKRLIVLVLLASTLLTGCNTARGFGEDIKHLGNSISRAAS"
     gene            complement(33957..34523)
                     /gene="efp"
                     /locus_tag="RN951_002467"
     CDS             complement(33957..34523)
                     /gene="efp"
                     /locus_tag="RN951_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004871142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDX2527454.1"
                     /translation="MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLR
                     RLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGD
                     NAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGA
                     VVKVPLFVQIGEVIKVDTRSGEYVSRVK"
     gene            34565..35593
                     /gene="epmB"
                     /locus_tag="RN951_002468"
     CDS             34565..35593
                     /gene="epmB"
                     /locus_tag="RN951_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P beta-lysylation protein EpmB"
                     /protein_id="HDX2527455.1"
                     /translation="MAHIVTLNTPSREDWLTQLADVVTDPDELLRLLNIDAEEKLLAG
                     RSAKKLFALRVPRSFIDRMEKGNPDDPLLRQVLTSQDEFVIAPGFSTDPLEEQHSVVP
                     GLLHKYHNRALLLVKGGCAVNCRYCFRRHFPYAENQGNKRNWQTALEYVAAHPELDEM
                     IFSGGDPLMAKDHELDWLLTQLEAIPHIKRLRIHSRLPIVIPARITEALVECFARSTL
                     QILLVNHINHANEVDETFRQAMAKLRRVGVTLLNQSVLLRDVNDNAQTLANLSNALFD
                     AGVMPYYLHVLDKVQGAAHFMVSDDEARQIMRELLTLVSGYLVPKLAREIGGEPSKTP
                     LDLQLRQQ"
BASE COUNT         8553 a         9821 c         9105 g         8418 t
ORIGIN      
        1 attaatgcgt tctcgctatt tgttacatca atattttgtt caggtacagt ttgcagcgcc
       61 gtcgctagcg ccaacggatt ccatgtcata tattattcca tatagattaa gtttaaatat
      121 taataaaatg aatatttgca atacgtaatt atcttaccag ctatagacaa aaaaaaacca
      181 tccaaatctg gatggctttt cataattctg agaaattagc tgcgctggcg caccgcttca
      241 aataagcaaa ttccggtcgc aaccgaaacg ttcagggaag aaacgcttcc agccatcggg
      301 atgctgatca actcatcgca atgttcacga gtcaggcgac gcataccttc accttccgca
      361 cccatcacca gcgccaggcg tccggtcatt ttgctctgat agagtgtatg atccgcctcg
      421 cctgccgtac cgacgatcca gatattctct tcctgcaaca tacgcatggt gcgcgcaagg
      481 ttagtcaccc gaatcagcgg aacgctttct gccgcgccgc aggctacttt tttcgccgta
      541 gcgttgagct gtgcggagcg atctttcggc acaatcaccg catgaacgcc tgcggcgtcc
      601 gcactacgca ggcacgcgcc gaggttgtgc ggatcggtta cgccgtcgag gatcagcagg
      661 aacggttgat cgagcgaagc gatcagatcc ggcagatcgt tttcctgata ctgacgtcct
      721 ggcttcacgc gggcgataat gccctgatgc acggcaccgt cgcttttctc gtcgagatat
      781 tggcggtttg ccaactggat aaccacgccc tgagactcaa gggcgtgaat cagcggtaac
      841 agacgtttat cttcacggcc ttttaaaata aagacttcct gaaaacgttc aggggcgcgc
      901 tccagcaggg cctgcactgc gtggatgccg taaatcattt cgctcattaa tgtactcgtt
      961 gtttacgttt tgcctgatgc actacgttta tccggcctac atgatctctg caatatattg
     1021 aatttgcgtg attatgtagg ccggataagg cgttcacgcc gcatccggca tgaacaaagc
     1081 gcattttgtc agcaatctaa ccctcttctt ttaaagaggg tattgatcac tctgccactt
     1141 ttttcttcgc cgcacgcttc gctttggtcg ctgcagctat tttctgcgtt ttcgccgatg
     1201 gctttttcgc ttttctcgcg tctttcttcg ccgctttcgg cttcgttttt ttctcaccgc
     1261 ggaaggcgct gtctggctca aagtttacct ttttaccgac ctgacgacgc ttgccgcctt
     1321 ttttacctgc atcgcctttt ttcgctttct cgcgcgccgt tttaccgacg ttgcgcggtg
     1381 cgcgttcgct ggagatcagg ctaaagtcga ttttgcgctc gtccatatta accgcttcga
     1441 cgcgaacttc cacgcgatcg cccaggcgat aagtctggcc gctggattcc cccatcaggc
     1501 gttgccctac ctggtcaaag cgatagtagt cattgtccag cgaagagaca tggaccagac
     1561 catcaatgaa caagtcgtcc agacggacga agaagccaaa gccagtgacg ctggaaatta
     1621 cgcctttaaa gacgttacct acctggtcga gcatgaagtc acacttcagc cagtcagcca
     1681 catcgcgcgt tgcttcgtcg gcacgacgtt ccgccatcga acagtgctga cccagttgca
     1741 gcatctcttc catcgaataa tggtagccgc cggtttcagt ggtgttgccc tgatgcccct
     1801 gctctttcgc cagcagatat ttaatggcgc ggtgcagcgt caggtctgga taacgacgaa
     1861 tcggcgaagt aaagtgcgca taggactgca atgccaggcc aaagtgacca cggttttctg
     1921 gatcgtaaat cgcctgtttc atcgagcgca gcagcatggt ttgcagcatt tctgcatcag
     1981 gacgatcggc aaccgactcc agcagctccg cgtagtcacg cggttccggc ttgttaccgc
     2041 ccggcagttc cagccccagc tccgccagca ctgaacggaa agaggtaatc gcttcggtgc
     2101 tcggcttgtc gtgaatacgg aacagtgccg gttctttcgc tttctcaacg aaacgcgccg
     2161 ccgagatatt cgccagaatc atgcactctt caattaattt gtgcgcgtcg ttacgctggg
     2221 tctgttcgat acgttcaata cggcgttcag cgttgaaaat gaacttcgct tcttcgctct
     2281 caaatgagat cccaccgcgt tcttcacggg ctttatccag cactttatag aggttatgca
     2341 actcttcgag atgcttaacc agcggggcgt actgctcgcg cagatcctga tcgccctgca
     2401 gaatatgcca gactttggtg taggtcagac gcgcgtgaga gctcatcacc gcttcgtaga
     2461 atttgtagcc cgtcaggcgg cctttcgacg aaaccgtcat ctcgcacacc atacacaggc
     2521 ggtctacctg cgggttgagc gaacacaggc cgttagagag cacttccggc agcatcggga
     2581 taacctgcga agggaagtac accgacgtgc cacggttacg cgcttctctg tccagcggcg
     2641 ttgacggacg cacatagtag ctgacgtcgg caatcgcgac ccataaacgc cagccgccgc
     2701 cgcgtttttt ctcgcagtaa actgcatcgt caaagtcacg ggcgtcttcg ccatcaatgg
     2761 tgaccagcgg taaatcgcgc agatcaacac ggcccgcttt tgcttcttcc ggcacttctt
     2821 ctttcagccc ggcaacctgt tgctcaacag cctgcggcca gatgtacgga atttcatggg
     2881 tacgcagagc gatatcaacc gccatgccgg tgcccatatt gtcgcccagc acttcgacga
     2941 ttttacccac cgctttggtg cggcgagtcg gacgctgagt cagttcgact acgaccacaa
     3001 agcccatccg cgcgcccatg atctgatcgg gcgggattaa gatatcgaag ctcagacggc
     3061 tgtcgtcagg aaccacaaag ccgacgcccg cttcggtaaa gtagcgacca acaatctggc
     3121 tggtttttgg caccagtacg cggacaatac gcgcttcacg acgaccttta cggtcagcac
     3181 ccagcggctg agccagcacc tgatcgccat gaatgcaggt tttcatctgc tcgctggaga
     3241 gatacaaatc atctttacgc ccttcaaccc gcagaaagcc gtagccatca cggtggccaa
     3301 taacggtacc tttcaccagg tcgaggcgtt ccggcagcgc atagcactga cgacgagtga
     3361 agaccagttg accatcgcgc tccatcgcgc gcaggcggcg acgcaggcct tcaagctgct
     3421 cttcgccttc aatgtgcagt tctaccgcca gctcatcacg gctggccggt ttttcacgtt
     3481 tggttaaatg ttcgaggata aattcccgac tagggatggg attcgcgtat ttttcagctt
     3541 cgcgttcctg gaaaggatct tgtgacatct cggttcctcc gttgtcatct ctgatgaaga
     3601 ttttcgtcac tccaccagca ataatttata aagcggttga ttctcttcaa ccaaatcggc
     3661 aagcgtgtag ttatccagtt ccgtaagaaa actttgcacg gccttagaaa gtgcctgttt
     3721 caacctacag gcaggtgtaa tgtggcaaaa ctcactgctg caattcacca gcgataaggg
     3781 ctccagctcg cgcaccacat caccaatacg tatcgcactc gccggtttac ccaggcgaat
     3841 gccgccattt tttccacgaa cagcagtcac gtagccggca cgactaagtt gattgattat
     3901 tttgaccata tgattacggg agacgccgta gacgtcagtc acttcagaaa tactggtcat
     3961 ccgcccttct ggcaatgacg ccatgtagat cagcgcacgt aatccgtaat cagtgaaact
     4021 cgttaactgc acatcaacct caaaagggaa atcgggaaaa aatacattta tattgatgat
     4081 aaaccagcca caagctgtgt cgctaattta tttcagttcg gggaaggaaa aaagcgagga
     4141 tttaacactg tgtcggatag cgtaatggct tacccgacac agcaatgtat cacactgttc
     4201 gcccggcagg caaaatatct gccaggcgta ccagaattac gcgtcgaacg ggtcgcgcag
     4261 aatcattgtt tcagtacgat ccggaccggt agagatgata tcgatcggca caccagtcag
     4321 ctcttcaata cgcttgatat agttcagcgc cgcctgcggc aggccgctac gatctttcac
     4381 gccgaaggtg gattcagacc agcccggcat ggtttcgtaa atcggctcta cacctttcca
     4441 gtcgtcagct gccagcggag tggtagtcac ttcgcgacca tccggcatac ggtaagccac
     4501 gcagagttta acctctttca ggccatccag aacgtccagt ttagtcaggc agaagccaga
     4561 cagggagttc agctgtaccg cacgacgaac ggcaacggtg tccagccagc cggtacgacg
     4621 acgacgcccc gtagttgcgc cgaattcgtt accctgcttg cagaggaact cgccagtttc
     4681 atcaaacagt tcggtcggga acggacctgc acctacacga gtggagtaag ctttgaggat
     4741 acccagaacg taatcaacat aacgcgggcc caggccggaa ccggtcgcca cgccaccagc
     4801 agtggtgttg gaagaagtta cgtacggata agtaccgtgg tcgatatcca gcagcgtacc
     4861 ctgcgcacct tcaaacatga cgaaatcgcc acgctgacgc gcctggtcga gcaggtcaga
     4921 aacgtcaacc accatagaag tcaggatgtc ggcaacagcc atcgtatcat ccagaacttt
     4981 ctggtaatca accgcttcag ctttgtagta gttaaccaac tggaagttgt gatattccat
     5041 cacttctttc agtttttcag cgaaggtttc tttgtcgaaa aggtcgccaa cacgcagacc
     5101 gcgacgtgct actttatctt cataagcagg cccgatacca cgaccggtgg tgccgatcgc
     5161 tttcgcgcca cgcgctttct cacgcgcgtt atccagcgca acgtgataat caaggatcag
     5221 cggacatgct tcagacagca gcagacgctc acgaacgggg atgccacggt cttccagttc
     5281 tttcatctct ttcatcagcg cggccggaga cagcacaaca ccgttaccga tgatgctggt
     5341 tacattctcg cggagaatac ctgatggaat aagatggaga acggtttttt caccgttgat
     5401 tacgagagta tggcctgcgt tgtgaccgcc ctggtagcgt acaacatatt tagcccgttc
     5461 agtcagaaga tcgacgatct tacctttacc ttcgtcaccc cattgggtgc ccagtacgac
     5521 gacgttgtta cccatttttc aaaatcaccg tttgcttaaa aatggattct accatcgctt
     5581 tttcagagtt acagcacttt ttgcactcaa aaatgacctc gatcagtctg ttttttgttc
     5641 agccaatcgt tttcctcaac atgtagtaga ccacaacgcc cgcaaccaca agtccaccgc
     5701 caaaacgacg taaaatatta tcgggcaaat tggtcatcgc agagatcatc ttcttccatg
     5761 ccttcgggta aagcatcggc cctaaacctt ccagtaccaa aaccagggca agcgccagcc
     5821 agattgtcga attcattcat tatccttata gaaaaagaaa accaccgaca tccctgagga
     5881 tgcggtggct ttattgacct gtaccgcagt cgttatatta acgcgttgcg gaagtcggcg
     5941 tcttcatgta gcggaagaaa tcgctatccg ggctcatgac catcacgtcc tgattgccag
     6001 agaagctgtt ctcataagca cgcaggctac ggatgaatgc gtagaagtct ggatctttac
     6061 tgaatgcatc agcaaacagt ttggctgctt cggcatcgcc ttcaccacgc atgatgcggc
     6121 cctgacgctc agcttctgcc agcgttctgg tcacttcata gtcggcagtc gcgcgcagtt
     6181 tttccgcttc ttcctgacct tgtgaacggt gacgacgcgc taccgcttca cgctcggcgc
     6241 gcatacggtt gtagatcgct tcagacactt cggtcggcag gttgatctgc ttgatacgca
     6301 catcgacaac ttcaataccc agcgccgcca tactgttcgg gttgatgacc ggaactttgc
     6361 ccttcgtctc agccgttacg cgctctgccg cttcggcaat ggcgttatct gccgccgggg
     6421 tagtaacttc atcttctgta cccgcagaac cggagttcag cgcgtcacgt acttcgaggg
     6481 tcagacgacc acgggaatcg gtgacgatat ctttcacgtc caggcgacca atttcagaac
     6541 gcagacggtc agagaactta cgtttcaaca gcacttccgc ttgcgaaatg tcgccaccac
     6601 ccgttgccag gtagtaacgg ctgaaatcgc tgatgcgcca tttgatgtaa gagtcgacga
     6661 tcaggtcttt cttctctttg gtcacaaagc ggtcggcctg gttgtccatg gtctgaatac
     6721 gtgcgtcgag cattttcacc gtttcaatga acggtatctt gaaatgcaga cccggctcat
     6781 aaaccagagg tttgttgtca tcgtcacgca gtaccttacc aaaacgcagc gtaataccgc
     6841 gctcaccttc tttgacgaca aagacagaca tgtaaagcac taccagcacg atgatgataa
     6901 tcgcgataac tgacttacgc atcgttattc cccctgacgc tggtagtcgt tacgctgcgc
     6961 gttggcgcgg cgttggtcca taatatcgcc ctgactggtg gacgacgtgt tgcttgctcc
     7021 actggttgtg gaggaagagg ctggcggcag acgcagcaga ttgctggcac cgttatcgct
     7081 cttcgccgca ggggcgttac cacctttcag catctggtct aacggcagaa ccatcaggtt
     7141 gccaccttta tcgttaacca gcactttgcg ggtgttaccc aacacttttt ccatcgtctc
     7201 gatatacaga cgctcgcgag taatttccgg cgcggcttta tattccggca gaagtttagc
     7261 aaagcgcgcc acttcaccct gagcttccag gatggtctgg gccttgtacg cacgcgcctc
     7321 ttcgaggata cgttgcgcct gaccgttcgc acgcggctga acttcgttgg tatacgcttc
     7381 tgcttcacga atgtattgct gttcgttttc acgcgcggca atcgcatcgt caaacgccgc
     7441 ttttacttct tccggcggac gagcagcctg gaagttgacg tccagcagcg tgatacccat
     7501 gtcatacgga cgaatcgtct cttccagttc gcgctgagta tcgctacgaa tcacggtacg
     7561 accttccgtc agaatgcggt ccatggtgta tttaccgata actccacgca gggcgctgtc
     7621 ggtagcctga cgcaggctgt catccgggct ggtcacgcta tacagatatt tttccggatt
     7681 ggtgacgcgg tactgcacgt tcatctcaac gcgcactacg ttctcgtccg acgtcagcat
     7741 cacaccagaa gcggccagtt cacgcacggc ttccacgttc accggtttga cttcgtcgat
     7801 aaacgtcggt ttccagttca gacccggctc aaccagatgg ctgaatttac caaagcgtgt
     7861 taccacgccg cgttcggctt ctttaatggt atagaaacca ctggccgccc agataatgac
     7921 aatcgctgcc gctgcgatgg taacgacacg accgccaagc tgcgggcgcg ggccttgcga
     7981 tgaactgcca ccgccagatc cggtgccttt accgccgccc agaccaccga gctttttgct
     8041 cagtttgcgg aagatatcat ctaaatcagg tggcccttga tcgcgaccgc ctttgtttcc
     8101 atttccctca gagttgccgc caggtttgct gcttccccac gggtcgcggt cttgtccgtt
     8161 attaccgggc tgattccacg ccatgtttgt gctccatatt tgttatgcgg tgatccctgt
     8221 tgtctttcga cgccagagga tatgactcca cgcttcagac gctacgccgt tagatcaggt
     8281 aatcgatcaa cgccggttct tgtttacaga ggcgacgcca gtcaacgatc ggcatacgaa
     8341 cttgcagact tacgctgccg tcctcctcca tccactcttt ttctattgcc tgaagctgat
     8401 aaaaacgact tctcagacgc ccttcctgcg gtggcagacg caatgtatgc tgcgccacct
     8461 cgccggaaag ccgctccgtc aaagcctgaa aaagctgtgg tatccccgct ccggtctgtg
     8521 cggaaagcca gacacggatc ggtttgttct cttcgtcccg atcaatacgc ggttcgaaat
     8581 cttccagcat atcgatcttg ttcatcacca gcagggttgg gatctcgtga gcgtcgatct
     8641 cttcaagaac cgtattcacc gcttcgatgt tttcttgtac acgcacatcc gccgcatcaa
     8701 tgacgtgcag cagtaatgtg gcttgccgcg tctcttgtaa cgtggcttta aatgccgcca
     8761 ccagatcgtg cggcaggtgg cgaataaacc ctacggtatc tgcaagtacg gtttcaccga
     8821 catctgcaac gtcaatacgc cgcaacgtcg ggtcgagggt ggcaaacaac tggtctgccg
     8881 cgtagacccg cgcttcggtg atgcgattga aaagggtaga tttaccggcg ttggtatatc
     8941 ccaccagcga aacagtagga acgtcggctt tgatacgcga ttgccgcccc tgctcacgct
     9001 gcttttcaac tctttccagg cgcgactgta tctgcacgat gcgattacgc aacaaacgac
     9061 ggtcggtttc gagctgggtt tcacccggac cacgcaaacc tatcccgcct ttctgtcttt
     9121 caaggtgggt ccagccacgc accaggcgcg tagccagatg gcgcagctgc gccagctcaa
     9181 cctgcaactt accctcatgg gtacgcgcac gttgggcgaa aatatctaaa ataaggccgg
     9241 tgcggtcgat aacacgacac tcgcacaaac gctccaggtt acgctcttgc gccgggctca
     9301 gggcatggtc aaaaagaacg accgaagcac ccgtcgcttt gacagcttcc gcaatttcaa
     9361 ctgctttacc ttcacctaca aaatactttg ggttcggcgc tttacggcta ccggtaatca
     9421 cctgcaatgc ttcgacaccg gcggaagaga ccagagattc aaactcctgg aggtcttcca
     9481 tatctttgtc ttgcgtaaaa tagatgtgta ccagtaccgc ctgctcacca gcatcataac
     9541 ggtcaaacaa gcgtataacc ctctaaatag atcagcgggg aacgcaggat cgctcgctcc
     9601 ccgtgtaaaa aaacagcccg aaaccttatt cggtttcttc gctgtcctgt tgcgcggaag
     9661 tattctgcgc gctgctacca tgatggtagt tactgctggt accgccaccg gcgttgttac
     9721 tgtgatgaga aaccgggcga gacgggacaa cagtagaaat cgcgtgcttg taaaccatct
     9781 ggctgaccgt gtttttcaac aggatcacga actgatcaaa agactcgatt tgcccttgca
     9841 gcttaatacc attcaccaaa taaatagaaa ctggaacacg ttcccgacgc agtgcgttca
     9901 ggaacggatc ttgtaaagat tgccccttag ccattctctc ttttccttat atgcttattt
     9961 gtactttgaa cctttcgatt ctgaaaaaat tgcgcacgat acgtctcaat tgtacacatt
    10021 cagcctgcga tagcaccaac aacctgtaat acttcgtcac gcgcctgttc tggtttttca
    10081 ctgtcaagcc agtgaacccc ttcccaacca cgcagccagg ttatctgccg cttcgccaac
    10141 tgtctcgtgg cgcaaacacc tcgataaacc atttcatcgt atgagatttc gccttcaagg
    10201 taagaccaca tctggcgata acccacgcaa cgaatggaag gcaagtccgt atgcaaatct
    10261 cctcgggcaa aaagcgcccg gacttctgct tcaaaacctg aagccaacat ctgatgaaaa
    10321 cgctgctcaa tgcgttgatg gagcagttca cggctcgccg gggcgatggc gaactgatgc
    10381 acctgatacg gtagagcgtc tcctgacgtt tgcgtcagtt ccgttaaagt tttacccgaa
    10441 atgaaaaaaa cttccagtgc ccgggaaagc ctttgtggat catttggatg aatccttgct
    10501 gccgcaaccg gatctacctc ctgaagttga cgatgcaatg actcccaacc ttgctctgcc
    10561 gcctgttgct caattctggc ccgtacttcc gggtctgccg acggtagcgg cgacaaccct
    10621 tccagcaatg ccttgaaata caacatcgta ccgcccacta acagtgggat ccgccccgcc
    10681 gcggtgatat cggccatttc cgccagcgca tcgcggcgaa aatcagcagc cgagtaagcc
    10741 tgcgacggat cgcgaatatc cagcaatcgg tgcggcgcgg cgagtaactc ttcagcgttc
    10801 ggcttcgccg tcccgatatc catccctttg taaataaggg cagaatcaac gcttatcaac
    10861 tctactggta aaattttacg cagctcaatg gctaacgccg ttttaccgga ggccgtcggc
    10921 cccatcaaaa aaatcgcctt aggcaggctc gccttactga tatcactcat ctttcagggc
    10981 ttttatcgcc ggatgtaaat caacagattg taacagacca cccggcggcg ttttcacaag
    11041 ttgcggacat aaccgttcca cgtccgccag cagggttatg gcctgtgcca ttgaccactg
    11101 cgcatgttcg ctcatcagat ttcgtgcaat ccactgcgca atattgccag gttcgaatac
    11161 ggactgcttc gccaggtagc ctatcagttc aggaatcaag atttgtaaat tttgttggcg
    11221 taagggtaaa ggcactgccc tgatggtcac atgctgtgca tctgactgga aatcaatacc
    11281 caattccgcc agggcagact gcgctttttc taatgccgat ttttcttcgg cagaaacttt
    11341 tagccgcaac ggaatcagca gcggctgggc gcaaacgggc gcttcacccg gcgtcaattg
    11401 tgcctgacgc agccaacgtt ctgccactgg caaggataaa agtgaaatgt tgccgtcgcg
    11461 ctccagcaac gcacagtcgg aatggacgat agtcagtacc cgaccaaaac tctgactgtt
    11521 cgccgcaagt gcaggttcct gcggttccgg cgcttttaat ttttgcatcg gcgcgggcgt
    11581 ttgcaaaagc tggcgataca cttcaccttg ctgtttctgg tagcctggct gcgcattcgg
    11641 ccagggggca gccggacgac tgcctgatgc tggcgcagga gtgtagcgcg gagctaccgg
    11701 ctcacgagct gccggttctg caaagtgatt gcgccccgcc gccacgcggt tttccggaat
    11761 ggaacgcggt gcaggttggg gttcatcgtc cagcggtagc ggcgtttcca gttgctgttg
    11821 tagcacgctc agcacgccct gatagataaa atcatgcacc agacgcgact gatggaaacg
    11881 cacttcgtgt ttggcggggt gcacgttgac gtccacctga tgtgggtcga tctccagata
    11941 caacacaaat gccggttgct gatcggcccc cagtttgtct tcgcaggcct ggcggatcgc
    12001 gtgattgatc aggcgatcgc gcatcatgcg accgttcacg tagcaatact gaatttctgc
    12061 cagtgcgggc gtggtgtgat ttggatcggc cacccagccg cgtagcgtga gatcgccgtg
    12121 ttgccattca atcgccagcg cttgttcaag aaaagcggtg ccgcaaatcg cgcctaagcg
    12181 ccgttctttt tgcccgcctt ccggcactgc gcggtactga cgcacaattt taccgttatg
    12241 cgacaggttg atcgtgacgt cgaaacgcgc cagcgcaatg cggcggatga tctcatcaat
    12301 gtggttaaat tcggttttct cggtgcgcag gaatttgcgc cgcgccgggg tgttgtagaa
    12361 cagatccagc acctccagcg tcgtccccac aggatgcgcc gccggtttta ccgtcacgtt
    12421 catatcgcgc ccttcggcat aggcctgcca ggcttcctgc tgttctgcgg tgcgtgaagt
    12481 gagcgtcagg cgggaaaccg aactgatact cgccagcgcc tcaccgcgaa agcccaggct
    12541 gataatggct tcgagatcgt ccagagaggc gattttactg gtggcatgac gagccagcgc
    12601 cagcgccagc tcatcttttt tgataccgca gccgttatca cgaatgcgga taagtttcgc
    12661 cccaccgcgt tcgatatcaa tatcgatacg cgtcgcacct gcatcgaggc tgttttccac
    12721 tagttctttg actaccgacg caggtcgctc gaccacctca cctgcggcaa tctggttcgc
    12781 cagttgtggc ggtaagacct gaattggcat caatcgtcct tagtttggca gcgtgcgatc
    12841 tggcgtcgtc accgtactgg cagtttgtgc cgttgcaccc tgcggcgcag attgcatcgg
    12901 atgcgcaagg aagtaattgc gcaggccttt gtaaatggct tctgccagct gttgttggta
    12961 atcgtcgctc gccagcaaac gttcttcgct gttgttgctg ataaaaccgg tttcgaccag
    13021 tactgatggg atatccggcg agcgcagaac gccaaggctg gcgtgttctg gtcgacgttt
    13081 atgtatttcg ccaatgcgtt gcaactgact gatcatactg gtcgctacat cataccctac
    13141 ccgctgggaa tgaccgaact gtaaatccag caccgcctgg cttaaatagg ggtcagactg
    13201 actgttcgcc agcacatcac ccgccccacc cagcagctcc gactgtttct cgtgctgctc
    13261 cagccagctg gccatttcac tgttggcgcg acggttagag agcacccata cggaagcgcc
    13321 agtcgcactg cggttcggtg cggcatcagc gtgaatcgac acgaggaaat tggcgttttg
    13381 cttacgtgcc acatcactgc gccccatcac cgagataaag taatccccgt cacgggttaa
    13441 aacgccttta aacatcggat cgtcattgag caaagtacgc aatttacgcg cgatggcgat
    13501 ggtgacattt ttctcccgcg taccaccggg gccgatagcg ccagggtcct gaccgccgtg
    13561 tccggcatca atagcgatga taattttatc gccagtgtta gccgtcgcgc gcgctgccgg
    13621 acgcgttacc gtattactgc tgataacacc cgtagtgcgg ttactttccg ttttaaacgg
    13681 attgcgcgcc ggttcgctga cgcgcggtgc gacaaccgca ggcgtttcaa cgcgtttcgc
    13741 aaccacgggc ggcggaggag gcggtggcgg cacatcggcg ttaatcgtaa agacgacagt
    13801 gtaattgctg ccattctgcc gcttcaccgc ttcggtttta ccgttttcgg taagatcgac
    13861 caccagccgt agcgtttgtg catctttagg cgttccagag cgaatcgcct tcaccagatt
    13921 attgccgctg aacaacaacg gcagtccctg aatcacgccc gtttgtttga tatcgagcgc
    13981 cacggtgcgt ttgctttgat ggctaaacgc ataatcagga tcgccaataa aactcaacgt
    14041 tatccgcgcc tgttgattac cgttagaaac ctgaatatca gagagcgtcg cggcacccac
    14101 cggcgtgcac agcagcagca gcgtcgctac caaccaattt ctgatgcgat acatcatccc
    14161 gccacctttc aaaggttaac cggctaaacg cgccagcaac aattcacccg cagaggaaac
    14221 cgcactcacg cgcgcctcac ggccttgtgc ctgataatca atgtgtattt cgacatccgg
    14281 gtcaggaaga acacctgtac cttgttgtgg ccactccacc aggcagatgg catcgttggc
    14341 aaaataatcg cggatcccca taaactccag ctcctcggga tcggcaaggc ggtacaaatc
    14401 aaagtgatag accattaagt tgtcgagcgt atagggttcg accagcgtat aagtggggct
    14461 tttgacatta ccctgatgac ccagagcctg taaaaagccc cggctaaagg tggttttacc
    14521 tgcgcctaaa tcgccataca gatagattac ggttgcgcca tcgcaggctt tcgctacccg
    14581 ctcgcccagg tctaatgttg cctgctcatc agggagcgga attactcgat tcatcatggt
    14641 ttttatcagt cacttccggg ttaacaatac gctgtagcgt ggaaaagaga tcggttgcca
    14701 gcatcccgcg cgttccaaaa cgcgccgcca gtacgtcagc tgccgcaccg tgcgcgacac
    14761 agcctgcaca ggctgcatca tacggcgaca gtttttgccc aagcaatgcg ccaataatac
    14821 cagagagcac atcgcccatg ccgccgctcg ccatgcctgc atttccggca tcaataatgc
    14881 ctaaagcgtc aggatgggcg gcgaccacgg ttccggcacc tttcagcacc gctacgccgc
    14941 cataacgttg taccagacgt ttggcgcaat gtaagcggtc actttcaatt tcagcgacgg
    15001 aacagcctaa caaccgtgcg gcctcgccag gatgcggcgt gatcacgcga ttgtgacgct
    15061 tatcgggatt gattgccagc aggttcaatg catcggcatc ccacaacatc ggtttgcgaa
    15121 aattctcaac tttttgcagt gcttttttcc cccactcttg ctggcccaga ccgggaccaa
    15181 tcaccaccac atcggcccat tccaggcttt cggtaagaga gtccatcgtc agttcatgca
    15241 ccatcaattc cggtcgtgca gtcagcagcg gcgcaatgtt ttcactgcgg gtcagtactc
    15301 ggactaaacc agcaccagca cgcagcgccg cttcccccgt catacgaata gcccccgccg
    15361 tgccgtgatc gccaccgata attaccagcc gcccgtgatc gcctttatgc gaagtcgggc
    15421 gacgcggttt tagccagtga gaaagttgtt ctgctgaaaa ccgctgaatt ttcgtctcct
    15481 gacctgccag ccaactatcc agccccagtg agtcaaaatg cagttgtccg gtaacatccc
    15541 gcgcttttcc agtgagcaag cctggtttca gcgcaataaa agtgatggtg tgatcggcgt
    15601 tgatcaccgc gcctggcgta gcgccagttt cagccagcag gccggaaggg atatcaaccg
    15661 ccacaatcgg cgcaggatgg gaattagcgt ggtcgattaa ctggctaatg gattcgcggg
    15721 gcgcttgccg caaaccggta ccgagcagcg catcaacaat cagatctacc gattcgggcc
    15781 agacaatatt cgaagcatgg atctcgccac ccgcgtttaa ccatgcttcg cgtgccagcg
    15841 cggcctcttc cggcaacggt ttgtcgctct cctgggccaa caacgtgacc tcaatgccga
    15901 ccgctttggc cagtcgcgcg accacgtagc catcgccgcc gttattacca tgaccgcaca
    15961 gcaccagcca gtggcgggcg tcaggatacg ccgaacgaca cacctggaat gcggcctcgc
    16021 cagcgcgaag catcagctca tagagtgtga gccccagcac atctgccgcc tcgcgttctc
    16081 cgcggcggat atcgtcggcg taccagacgg tgtgtggtat acttacgggg tttttcttca
    16141 ttgtatggtc cgtcatgtca gagcccctcg atctcaatca gttagcgcaa aaaattaaac
    16201 agtgggggct ggaactgggc tttcagcagg taggtattac cgataccgat ctcagcgagt
    16261 ccgagcccaa actgcaagca tggctggaca aacaatacca cggcgaaatg gactggatgg
    16321 cacgtcacgg tatgctgcgc gctcgccctc atgagttatt gcccggtacg ctgcgcgtga
    16381 tcagcgtgcg gatgaattac cttcctgcta acgccgcatt tgccagcacg ctgaaaaacc
    16441 ccaaactcgg ctatgttagc cgttatgcgc tgggccgtga ctatcacaaa cttctgcgca
    16501 accgactcaa aaagctgggc gagatgattc agcaacattg tgtttcgctg aattttagac
    16561 cgtttgtcga ttctgcgcct attctcgagc gcccgttagc tgaaaaagct gggctcggct
    16621 ggacaggtaa gcactcactt atcctcaatc gcgaggccgg ttcgttcttc tttttaggcg
    16681 aattgctggt cgatattccg ctgcccgtgg atcaaccagt cgaggaagga tgcggcaaat
    16741 gcgtggcctg tatgacgatt tgcccgaccg gtgccatcgt cgagccatat accgtcgatg
    16801 ctcgccgctg tatctcttat ctcaccatcg aacttgaagg ggcgatcccg gaagagttgc
    16861 gaccgttaat gggaaaccgt atttacggtt gcgatgactg ccagcttatc tgcccgtgga
    16921 atcgctattc acaactcacc acagaagagg atttcagccc gcgtaagccg ctacacgcac
    16981 cggaactcat tgagttattc gcctggagcg aagagaagtt tttaaaagtc acggaaggat
    17041 cggcgattcg tcgtattggt cacctgcgtt ggctgcgtaa tatcgccgta gcattaggca
    17101 atgccccttg ggatgaaacg attttgacag cgctggaaag tcgtaaaggt gagcacccac
    17161 ttctcgatga gcacatagcg tgggcgattg cgcagcaaat agagagacga aatgcgtgca
    17221 tagtcgaagt gcaattgccg aaaaaacagc gtctggttcg ggtgattgaa aaagggttac
    17281 cgcgtgacgc ctgattcatc cacagcttgt gaataaaaat aaaaacgcat tgcaattcaa
    17341 gacgaataaa atcgtcaagt gatcgactcg acaaaacgga atcttaattt ttaacttatc
    17401 tatcaatagg ttaaaaaaat actattcacc gtgcgaagtt tctttgaaat taagattaca
    17461 gcctgaggct gtggataact ctgtttacaa gagtttgtca gagacaacaa aaaccagcaa
    17521 taacgcatcg cgtcgctgtg gatattttat tgagagaaga atttggagcg ggaaacgaga
    17581 ctcgaactcg cgaccccgac cttggcaagg tcgtgctcta ccaactgagc tattcccgct
    17641 tgggtggtct gtgccttaca gcactttcaa attttggagc gggaaacgag actcgaactc
    17701 gcgaccccga ccttggcaag gtcgtgctct accaactgag ctattcccgc ttgggtggtc
    17761 tgtgctttgc agcacttttc aaattttgga gcgggaaacg agactcgaac tcgcgacccc
    17821 gaccttggca aggtcgtgct ctaccaactg agctattccc gcgtactact taattttgct
    17881 ttcgtaattt tcgcatttct gcgtcgttac gggaggcgca ttatacgaga aatctttccc
    17941 tctgcaaccc cccaaaaaag ttttttttgc gtttttatct caagtgctga aattatcagc
    18001 aagacgttca atttagcgtc aaaatcacgc cgccgcaagt ggattccggc gcttacgtga
    18061 ccaggaaaaa ttttacagct tgataaaatg ctcgcggtag taagccagct ccgccaccga
    18121 ttcacggata tcatccatcg cctgatgcgt cccctgcttg gtaaaaccat ccagaatttc
    18181 cggcttccag cggcgcgcca gctctttcag ggtgctgaca tcgagataac ggtagtggaa
    18241 gtaggcttcc agctccggca tgtatttaaa caggaaacga cggtcctgac cgatgctgtt
    18301 accgcaaatc ggcgattttc ccgcaggcac ccactgtttt aaaaattcga gcgttgccag
    18361 ttcagcttcc cgatcgccca tcgtgctcgc tttcacgcgc tctaccagcc cgctggcggt
    18421 atgggtgcgc acgttccagt catccatcag cgccagctgt tcatcagact ggtgtactgc
    18481 aatggtcggc ccttctgcca gaatattcag gttggcatcg gtcaccagcg tggcaatctc
    18541 aataatgcga tcgcgctcgg gatccagacc ggtcatctca agatcgatcc aaatcaggtt
    18601 gttttcattg gcactcatgc tattttccac ccattcacag tgactatatt gatccacaat
    18661 tgcgtgtatc atagatgttt tgcccatcag gggcgaccag gagtctgtac gattgagtaa
    18721 aaataaactc tccaaaggcc agcagcgccg cgtgaacgcc aatcaccagc gtcgtcttaa
    18781 aacgtctaag gagaagcccg actacgacga caatctgttt ggcgagcctg atgaaggtat
    18841 cgtcatcagc cgctttggta tgcacgctga tgtggaatcc gccgatggcg acgttcaccg
    18901 ctgcaatatt cgccgtacca tccgttcgct ggtaaccggc gaccgcgtag tctggcgtcc
    18961 gggtaaaccg gcggcggaag gcgtaaatgt caaagggatc gtggaagcgg tgcatgagcg
    19021 tacctcggtg ttgacgcgtc cggatttcta cgacggcgta aaacctattg ccgccaacat
    19081 cgaccagatt gtcattgtct ccgccatttt gccggagctg tcgctcaata ttatcgaccg
    19141 ttacctggtg gcctgcgaaa ccttgcagat tgagccgatt attgtgctca acaagataga
    19201 cctgctggac gacgaaggca tggcgttcgt caacgagcag atggatatct accgcaatat
    19261 cggttatcgc gtattgatgg tttccagcca tactcaggat gggctaaaac cgctggaaga
    19321 ggcgttgacc gggcgcatca gcatttttgc cgggcagtct ggcgtcggca aatccagcct
    19381 gctgaatgcg ttgctggggc tgcaaaaaga gatcctgacc aacgatatct ctgacaactc
    19441 ggggctcggt cagcacacca cgaccgccgc tcggctgtat cacttcccgc acggcggtga
    19501 tgtgattgac tccccaggag tgcgtgagtt cggcctctgg cacctggagc cggaacaaat
    19561 cactcagggc tttgtcgaat tccatgacta tttaggcctg tgtaaatatc gcgattgcaa
    19621 acacgatacc gatccgggct gcgctatccg ggaagcggtt gaggaaggga aaatcgcgga
    19681 aacccgtttc gaaaactatc accgtattct ggaaagcatg gcgcaggtaa aaacgcgtaa
    19741 aaacttttct gatacggatg actgacaatt aagctaaccg tcgttagaat cgtccccttt
    19801 ttttcaggat ccggcatgta ggccggatca ggaacgacaa aacaatggcc tggaggctac
    19861 cttgttaaat tcatttaaac tttcgctaca gtacattctg ccgaaactat ggcttactcg
    19921 cctggcgggt tggggcgcaa gcaagcgggc aggatggctg acaaaactgg ttatcgatct
    19981 gttcgttaaa tactacaagg tcgacatgaa agaggcgcaa aagccggaca ccgccagcta
    20041 ccgcaccttt aacgaattct ttgtccgtcc gctgcgtgac gaagtacgcc caatcgatac
    20101 cgatccgaat gtactggtca tgcctgccga tggcgttatc agccagttgg gtaaaatcga
    20161 agaagataaa atcctgcaag ccaaaggcca caactacagc ctcgaagccc tgctggcagg
    20221 caactatctg atggcggacc tgttccgcaa cggtacgttt gtgaccactt acctctcccc
    20281 gcgtgactac caccgcgtac acatgccgtg caacggtatt ctgcgtgaga tgatctacgt
    20341 gccgggcgat ctcttctccg ttaaccatct cacggctcag aacgtgccga atctgtttgc
    20401 ccgtaacgaa cgcgtgattt gccttttcga taccgaattt ggcccaatgg cgcagattct
    20461 ggtcggagcg acgattgttg gcagcattga gacggtctgg gcgggcacca ttacgccgcc
    20521 gcgcgaaggt atcatcaagc gctggacctg gcctgccggg gaaaacgacg gttctgtggc
    20581 actgctgaaa ggccaggaaa tgggtcgctt taaactcggt tccaccgtta tcaacctgtt
    20641 tgcaccgggt aaagtgaatc tggttgagca actggaaagc ctgtctgtca cgaaaattgg
    20701 ccagccgctg gcagtatcta ccgaaacctt tgttacgcca gacgctgaac ctgccccgct
    20761 tcctgctgaa gagatcgaag cagaacacga cgccagccca ttggttgacg acaaaaaaga
    20821 ccaggtctaa tccatcaaag gaaacgctga cgtgcgcctg attatcactt ttctgatggc
    20881 ctggtgcctc agttgggggg cgtacgccgc gacggccccc gatagcaaac aaatcactca
    20941 ggaactggag caggcaaaag cggcgaaacc cgcacagccg gaagtcgtag aggcgctcca
    21001 gtctgcctta aatgcgcttg aggaacgaaa aggttccctt gagcgcatca aacaatatca
    21061 gcaagttatc gataattatc cgaaactctc cgctactctg cgcgcacaat taaacaacat
    21121 gcgtgacgag ccgcgcagcg tgtcgccggg aatgtctacc gacgcgctga atcaggaaat
    21181 tctccaggtc agcagccagt tgctggataa aagccgtcag gcccagcaag agcaggagcg
    21241 cgcccgcgag attgccgatt cgctgaatca actgccgcaa cagcaaaccg acgcccgccg
    21301 tcagttaaat gagatcgagc gccgcctggg aacgcttacc ggcaatactc cgctcaatca
    21361 ggcacaaaat ttcgcgttgc agtctgactc tgcacgtctt aaggcgctcg ttgatgaact
    21421 ggagctggcg cagctgtctg ccaataaccg ccaggaatta gcgcgcttac gctcagagct
    21481 ggcggaaaaa gagagccagc aactggatgc gtatttgcag gccttgcgta atcaattaaa
    21541 cagccaacgt cagcttgagg cggagcgggc gctggaaagt accgaattgc tggcagaaaa
    21601 cagcgccgat ttgccgaaag atatcgtcgc gcaattcaaa attaaccgcg aactatcggc
    21661 ggctttgaat caacaggcgc agcggatgga tctcgttgcc tcgcaacagc gtcaggctgc
    21721 cagccagacg ttacaggtcc ggcaggcgtt gaatacgctg cgtgaacagt cgcaatggct
    21781 gggatcgtcc aatctgctcg gcgaagcgct tcgggcgcag gtggcacggc tgccggaaat
    21841 gccgaaacca caacagcttg ataccgaaat ggcgcagttg cgtgtgcaac ggttacgtta
    21901 tgaggatctg cttaataaac agccgctgct acggcaaatt catcaggccg acggtcagcc
    21961 gctgactgcc gagcaaaacc gtattctgga agcacaactg cgcactcagc gtgagttgct
    22021 gaactcattg ttgcagggtg gcgacacgct actattggaa ctgaccaagc tgaaagtctc
    22081 caacgggcaa ctggaggatg cgctgaaaga ggtgaacgaa gcaacgcacc gctatctgtt
    22141 ctggacctct gacgtgcgcc cgatgaccat cgcctggccg ctggaaatcg cccaggatct
    22201 gcgtcgtctc atttcgctgg acaccttcag tcagttgggc aaagccagtg tgatgatgct
    22261 gaccagcaaa gagacaattt tgccgctgtt tggcgcgttg attctggtcg gttgcagtat
    22321 ttactcgcgc cgctatttca cccgttttct tgaacgttcg gcggcgaaag ttggcaaagt
    22381 gactcaggat cacttctggc tgacgttgcg cactcttttc tggtcgattc tcgtcgcgtc
    22441 accgttaccg gtgctgtgga tgacgctggg ttacggcttg cgcgaggcgt ggccttatcc
    22501 gctggcggtc gcgattggcg atggtgtaac ggccaccgtg ccgctgctgt gggtagtgat
    22561 gatttgcgcc acctttgccc gcccgaacgg cttgtttatc gctcattttg gctggccgcg
    22621 cgaacgtgtt tcccgtggga tgcgctacta cctgatgagc atcgggctta ttgtgccgct
    22681 gattatggcg ctgatgatgt tcgataacct cgacgaccgt gaattctccg gttcgctggg
    22741 acggctttgc tttatcctca tttgcggtgc gctggcggtg gtcaccctca gcctgaaaaa
    22801 ggccgggatt ccgctgtatc tcaacaaaga gggcagcggc gacaacatta ccaaccatat
    22861 gctgtggaac atgatgattg gcgcgccgtt ggttgccatt ctggcgtcgg cggtgggtta
    22921 tctggcaacg gcacaggcgc tgttagcgag gcttgaaacc tcggttgcca tctggttcct
    22981 gctactggtg gtttatcacg ttatccgccg ctggatgctg atccagcgcc gcaggctggc
    23041 gtttgatcgg gcgaagcatc gccgggcaga gatgttagcg caacgtgcgc gtggcgaaga
    23101 ggaagcgcat catcacagta gcccggaagg agcaattgaa gtcgatgaaa gcgaagtcga
    23161 tctcgatgcc atcagtgcgc aatccttgcg gctggtgcgc tcaattttga tgttgatcgc
    23221 cctgctttct gtcattgtgc tgtggtcaga aatccattcc gctttcggct tcctcgaaaa
    23281 tatttcgctg tgggatgtca cctccacggt acagggcgta gaaagtctgg agccaattac
    23341 cctcggtgcg gtgctgattg ccattctggt gtttatcatc accacgcagc tggtgcgcaa
    23401 cttgcccgcg ctgctggaac tggcgatttt gcagcacctg gatttaacgc cgggtacggg
    23461 ttacgccatc accaccatca ccaaatatct gctgatgctg attggcgggc tggtcggctt
    23521 ctcaatgatt ggtattgagt ggtcgaaatt gcagtggctg gttgccgcgc tcggtgttgg
    23581 tctcggtttt ggtttgcagg aaattttcgc caactttatc tctggtctga ttatcctgtt
    23641 cgaaaaaccg attcgcattg gcgatacggt gacaattcgc gatctcaccg gtagcgtgac
    23701 gaaaattaac acccgcgcca ccaccatcag cgactgggac cgtaaagaga taatcgtgcc
    23761 gaacaaggcg tttattaccg agcagtttat caactggtcg ctctctgact cggtcacgcg
    23821 cgtggtgttg acgataccgg cccctgccga tgccaatagc gaagaagtga cggaaatcct
    23881 gctcaccgca gcgcgtcgct gctcgctggt gatcgacaac ccggcaccgg aagtcttcct
    23941 ggtggatctg caacagggga ttcagatttt cgagctgcgt atttacgccg ctgagatggg
    24001 tcaccgtatg ccgctacgcc atgagatcca ccagctgatt ctggctggct tccatgccca
    24061 cggtatcgat atgccattcc cgcccttcca gatgcgtctg gaaagcctca acggtaaaca
    24121 aacggggaga acgctgacgt ctgcgggcaa aggtcgtcag gcgggaagtt tgtaagtttg
    24181 tgtgccggat gaaccaatcc ggctcacaaa caaaactgat agcgcagaaa aaactgccac
    24241 agccagtagc cgaaaatagc cagcgcggtg gcgtacataa accagccgcg tttttttcgc
    24301 cacaaagcga accagagaaa agggaaaaag agcggtaacg tcattatcac accaacatca
    24361 cgggtatcgt cttcttcgag atacatcaac acatcgcaga cgttgttaat cccgcgtcca
    24421 tcaatcatcc actctttgtc cagcgcggaa gtgatggtta tccagaggaa cgccacaata
    24481 aaccagatgc agcataagac aaacatgcgc gcactcataa ggtaaccggt cgcttaattt
    24541 cgctatagcg catacgaaac aaatcgccgt atcccactaa ttccccgcga aaaaccagac
    24601 atcggataag ataagcgcaa taaatatccg gcaggtttcc ccaccgttta ccatcgcgat
    24661 ctttgagggt gttaatggtg ctacccacca ccatcgccac tttacgggtg tggcaggcat
    24721 cgacaaaaga gagaatcgtc tgctctattt ccgctacatc cccggcagaa aattgcagcg
    24781 ccctgatttc atcttcggtt attgccgggt cccggctggt gtcatccata acatttcctg
    24841 tctttacgcc ctatcgtcag gtagacgata gggcatcggg ttattccacc gcccactgcg
    24901 gattttttgc cactctgctg caatagttct ggtaaatcgc catcgctaac agcgagaaga
    24961 agacagggcc gccaatcatc cacaatgtgc tgtcccagtc tccggcttca accacaggtt
    25021 gaatgatggt gaagacgttc gcaaatgtca ccaccagtac gacaaccact gtcgcaatca
    25081 ttgccgacaa atgcgttttg aaaatcacaa acggtctgtc gagatcctga cgtgctttaa
    25141 agaacgggaa agccagcgcg aggaacaggt aaggaagcgt catagacacg ttcgccatca
    25201 gcgtcagctt gttaaagaac gccgatgcgg taccgccacc aaacgaaacc agcaggatga
    25261 agacagtaac caacccgcac tgcatccaca tggcgataga cggcatcccc atcgcattca
    25321 ggcgcgtcat cggttccggc cacaatgctt tcggcgtccc ctggatgatg gctttcaacg
    25381 gtgaatagca aagcgtaaag aacgcaccgg tataggcgag gaacatcgaa agtccagtaa
    25441 tacgcgcaaa ccatacgccc agcgacaatg acgcttcagg tgacaaatgc agtgcattac
    25501 ccagcgtcat cccaaggctc ttcatcagca cataggtaat attgccgagg ttaacggaac
    25561 cattacttaa tacctgctgc cagtttgtgc tgacgcccca taaaaatatt gccagcgaat
    25621 aaccgattga aataacaata gcggcaaaaa caataccttt ggcaaagttc ttttctggat
    25681 tttccgtttt atcgaccaga ccaccaaccg cttcaattcc gccataggca aaaatggcaa
    25741 ataccacaaa cgatagcatt gccagaccgg actgataacc cgggttcggt gatgcaagga
    25801 aattaatatc ctgcgcgaaa tgcccaccat ttaataacaa aatagtaatg cttactaaca
    25861 gcaatactaa attcagacac attactgcaa taccgcccac cgcagtaatg cgggcaattt
    25921 tattaatccc cttagaagca acgacggtga ccagaatcat ccatgccaca gccagcagac
    25981 caaccacctg cgtaggctcc agtccggcaa tacgccagtg ctgggtcatg tcgctaccat
    26041 agaggaatgt tgagaacggt acccaaactt tcgcggaggt actcaccatc cagatgatat
    26101 aagaggaaaa ccacataaac gtaccaatga aggcaaaacg tggtccgaca ctattattca
    26161 tccaggaata gataccgcct tcttctttgc gataagcagc tcccatttca gccatcatta
    26221 aggcgaatgg aataaagaat aacaatgcag aaaatatata aaagggaatc gcactataac
    26281 ccattaagta ataagccgat gggctattgg caaatccaaa tacggaagta aagatcatca
    26341 atatgagtcc tatcagactc atctttttta tcgtgtgagg catgaaacca tccttcattt
    26401 cagcgcgtgt ataacacgtg cccactgaac tgcactgcgc aacattgagc aggcagcgta
    26461 aaaaccaata cagaattgat acctggatga tatcaaatat ccagtcttaa attgtggcct
    26521 ttaacggaaa aatgaaaaca tatgctacag aatggcgctt atcacgccat tcttcgctgt
    26581 taattcagta atttttcaga attatgcccg gtcaacgcta aaggcgatga cttcagccag
    26641 tgtctccgcg cccagcgcca acatcaccag acgatcaaca cctaatgcca cgccggaaca
    26701 gtcaggcata ccgactttca aggcttcaat cagattctgg tcaatggggt gctgcggcaa
    26761 accgcgcgcc gcgcgcttac ggttatcttg ttcaaagcgt tgttgctgct cacgggcatc
    26821 cgtcaattca tggaaaccat tcgccagctc aataccttta taataaacct caaagcgttc
    26881 agcgacccga tgatcttcgg tactgatttg cgccagtgat gcctggctgg ctggaaagtg
    26941 gtacacaaag gtcggttttt ctttgccaaa atttggctct acgccaaagg taaacagcaa
    27001 ttgtagcagc gtgtcgcggt cttcttcggt atcagcaaca ttgctcaaat ccagtttcgc
    27061 tgcgacttcc cgcagttgcg ttttgtcggc agagagcggg tcaatttcca gataacgcaa
    27121 gaaagcttgt tgataagaaa ggctttctgc tgccgggcag tccagcacct gttgtaagag
    27181 atcgtccacc tcgttcatca accggtacat atcatagtgc ggtcgatacc actccagcat
    27241 agtgaactca gggttgtgat aacgccccat ctcttcatta cggaagctgc ggcacagctg
    27301 gaataccggc ccacaaccgg caaccagcag gcgtttcata tggtattccg ggctggtcat
    27361 taaccagaga ttcatcccct gcgaatgccc ggggccaacg aaacgtgtct caaacgggac
    27421 caaatgaata tcggttaccg tcgcctggct catacaaggc gtctccacct ccagcactcc
    27481 acgatcggca aagaaacgac ggatctccgc cataatcgcc gcgcgtttta ataagttagg
    27541 aatggatgcg ctcggctgcc aggatgccgt ttcgctcata gttaaatctc cagtttttga
    27601 caagggcacg aagtctactc gcaacgcgac ggcgagacaa attttacgca ggaatcaaac
    27661 agcggtgggc agtgactaaa aaaagtacga tctgatggtt tagtaattaa attaatcatc
    27721 ttcagtgata atttagccct cttgcgcact aaaaaaatcg atctcgtcaa atttcagact
    27781 tatccatcag actatactgt tgtacctata aaggagcagt ggaatagcgt tcgcagaccg
    27841 taactttcag gtacttaccc tgaagtacgt ggctgtggga taaaaacaat ctggaggaat
    27901 gtcgtgcaaa cctttcaagc cgatcttgcc attgtaggcg ccggtggcgc gggattacgt
    27961 gctgcaattg ctgccgcgca ggcaaatccg aatgcaaaaa tcgcactaat ctcaaaagta
    28021 tacccgatgc gtagccatac cgttgctgca gaagggggct ccgccgctgt cgcgcaggat
    28081 catgacagct tcgaatatca ctttcacgat acagtagcgg gtggcgactg gttgtgtgag
    28141 caggatgtcg tggattattt cgtccaccac tgcccaaccg aaatgaccca actggaactg
    28201 tggggatgcc catggagccg tcgcccggat ggtagcgtca acgtacgtcg cttcggcggc
    28261 atgaaaatcg agcgcacctg gttcgccgcc gataagaccg gcttccatat gctgcacacg
    28321 ctgttccaga cctctctgca attcccgcag atccagcgtt ttgacgaaca tttcgtgctg
    28381 gatattctgg ttgatgatgg tcatgttcgc ggcctggtag caatgaacat gatggaaggc
    28441 acgctggtgc agatccgtgc taacgcggtc gttatggcta ctggcggtgc gggtcgcgtt
    28501 tatcgttaca acaccaacgg cggcatcgtt accggtgacg gtatgggtat ggcgctaagc
    28561 cacggcgttc cgctgcgtga catggaattc gttcagtatc acccaaccgg tctgccaggt
    28621 tccggtatcc tgatgaccga aggttgccgc ggtgaaggcg gtattctggt caacaaaaat
    28681 ggctaccgtt atctgcaaga ttacggcatg ggcccggaaa ctccgctggg cgagccgaaa
    28741 aacaaatata tggaactggg tccacgcgac aaagtctctc aggccttctg gcacgaatgg
    28801 cgtaaaggca acaccatctc cacgccgcgt ggcgatgtgg tttatctcga cttgcgtcac
    28861 ctcggcgaga aaaaactgca tgaacgtctg ccgttcatct gcgaactggc gaaagcgtac
    28921 gttggcgtcg atccggttaa agaaccgatt ccggtacgtc cgaccgcaca ctacaccatg
    28981 ggcggtatcg aaaccgatca gaactgtgaa acccgcatta aaggtctgtt cgccgtgggt
    29041 gaatgttcct ctgttggtct gcacggtgca aaccgtctgg gttctaactc cctggcggaa
    29101 ctggtggtct tcggccgtct ggccggtgaa caagcgacag agcgtgcagc aactgccggt
    29161 aatggcaacg aagcggcaat tgaagcgcag gcagctggcg ttgaacaacg tctgaaagat
    29221 ctggttaacc aggatggcgg cgaaaactgg gcgaagatcc gcgacgaaat gggcctggct
    29281 atggaagaag gctgcggtat ctaccgtacg ccggaactga tgcagaaaac catcgacaag
    29341 ctggcagagc tgcaggaacg cttcaagcgc gtgcgcatca ccgacacttc cagcgtgttc
    29401 aacaccgacc tgctctacac cattgaactg ggccacggtc tgaacgttgc tgaatgtatg
    29461 gcgcactccg caatggcacg taaagagtcc cgcggcgcgc accagcgtct ggacgaaggt
    29521 tgcaccgagc gtgacgacgt caacttcctc aaacacaccc tcgccttccg cgatgctgat
    29581 ggcacgactc gcctggagta cagcgacgtg aagattacta cgctgccgcc agctaaacgc
    29641 gtttacggtg gcgaagcgga tgcagccgat aaggcggaag cagccaataa gaaggagaag
    29701 gcgaatggct gagatgaaaa acctgaaaat tgaggtggtg cgctataacc cggaagtcga
    29761 taccgcaccg catagcgcat tctatgaagt gccttatgac gcaactacct cattactgga
    29821 tgcgctgggc tacatcaaag acaacctggc accggacctg agctaccgct ggtcctgccg
    29881 tatggcgatt tgtggttcct gcggcatgat ggttaacaac gtgccaaaac tggcatgtaa
    29941 aaccttcctg cgtgattaca ccgacggtat gaaggttgaa gcgttagcta acttcccgat
    30001 tgaacgcgat ctggtggtcg atatgaccca cttcatcgaa agtctggaag cgatcaaacc
    30061 gtacatcatc ggcaactccc gcaccgcgga tcagggtact aacatccaga ccccggcgca
    30121 gatggcgaag tatcaccagt tctccggttg catcaactgt ggtttgtgct acgccgcgtg
    30181 cccgcagttt ggcctgaacc cagagttcat cggtccggct gccattacgc tggcgcatcg
    30241 ttataacgaa gatagccgcg accacggtaa gaaggagcgt atggcgcagt tgaacagcca
    30301 gaacggcgta tggagctgta ctttcgtggg ctactgctcc gaagtctgcc cgaaacacgt
    30361 cgatccggct gcggccattc agcagggcaa agtagaaagt tcgaaagact ttcttatcgc
    30421 gaccctgaaa ccacgctaag gagtgcaaca tgacgactaa acgtaaaccg tatgtacggc
    30481 caatgacgtc cacctggtgg aaaaaattgc cgttttatcg cttttacatg ctgcgcgaag
    30541 gcacggcggt tccggctgtg tggttcagca ttgaactgat tttcgggctg tttgccctga
    30601 aaaatggccc ggaagcctgg gcgggattcg tcgacttttt acaaaacccg gttatcgtga
    30661 tcattaacct gatcactctg gcggcagctc tgctgcacac caaaacctgg tttgaactgg
    30721 caccgaaagc ggccaatatc attgtaaaag acgaaaaaat gggaccagag ccaattatca
    30781 aaagtctctg ggcggtaact gtggttgcca ccatcgtaat cctgtttgtt gccctgtact
    30841 ggtaaggagc ctgagatgat taatccaaat ccaaagcgtt ctgacgaacc ggtattctgg
    30901 ggcctcttcg gggccggtgg tatgtggagc gccatcattg cgccggtgat gatcctgctg
    30961 gtgggtattc tgctgccact ggggttgttt ccgggtgatg cgctgagcta cgagcgcgtt
    31021 ctggcgttcg cgcagagctt cattggtcgc gtattcctgt tcctgatgat cgttctgccg
    31081 ctgtggtgtg gtttacaccg tatgcaccac gcgatgcacg atctgaaaat ccacgtacct
    31141 gcgggcaaat gggttttcta cggtctggct gctatcctga cagttgtcac gctgattggt
    31201 gtcgttacaa tctaacgcat cgccaatgta aatccggccc gcctatggcg ggccgttttg
    31261 tatggaaacc agaccctatg ttcaaaacga cgctctgcgc cttattaatt accgcctctt
    31321 gctccacatt tgctgcccct caacaaatca acgatattgt gcatcgcaca attaccccgc
    31381 ttatagagca acaaaagatc ccgggtatgg cggtggcggt aatttatcag ggtaaacctt
    31441 attactttac ctggggctat gcggacatcg ccaaaaagca gcccgtcaca cagcaaacgt
    31501 tgtttgagtt aggttcggtc agcaaaacat ttactggcgt gcttggtggc gacgctattg
    31561 ctcgagggga aatcaagtta agcgatccca caacaaaata ctggcctgaa cttaccgcta
    31621 aacagtggaa tgggatcaca ctattacatc tcgcaaccta cactgctggc ggcctgccat
    31681 tgcaggtgcc ggatgaggtg aaatcctcaa gcgacttgct gcgcttctat caaaactggc
    31741 agcctgcatg ggctccagga acacaacgtc tgtatgccaa ctccagtatc ggtttgttcg
    31801 gcgcactggc tgtgaagccg tctggtttga gttttgagca ggcgatgcaa actcgtgtct
    31861 tccagccact caaactcaac catacgtgga ttaatgtacc gcccgcagaa gaaaagaatt
    31921 acgcctgggg atatcgcgaa ggtaaggcag tgcatgtttc gcctggggcg ttagatgctg
    31981 aagcttatgg tgtgaagtcg accattgaag atatggcccg ctgggtgcaa agcaatttaa
    32041 aaccccttga tatcaatgag aaaacgcttc aacaagggat acaactggca caatctcgct
    32101 actggcaaac cggcgatatg tatcagggcc tgggctggga aatgctggac tggccggtaa
    32161 atcctgacag catcattaac ggcagtgaca ataaaattgc actggcagca cgccccgtaa
    32221 aagcgattac gcccccaact cctgcagtac gcgcatcatg ggtacataaa acaggggcga
    32281 ccggcggatt tggtagctat gtcgcgttta ttccagaaaa agagctgggt atcgtgatgc
    32341 tggcaaacaa aaactatccc aatccagcga gagtcgacgc cgcctggcag attcttaacg
    32401 ctctacagta aaattccatc gggtccgaat tttcggacct tttctccgct tttccttgct
    32461 gtcatctaca cttagaaaaa aaccagtaag gaaacattta tgcgcctgct ccctctcgtt
    32521 gccgcagcga cagctgcatt tctggtcgtt gcctgcagtt ctcctacgcc gccgcgtggc
    32581 gtgaccgtag taaataattt cgacgccaaa cgttatctcg gtacctggta tgagattgcc
    32641 cgttttgatc accgctttga acgtggactg gaaaaagtca ccgcaacata cagcctgcgt
    32701 gatgacggcg gcctgaatgt cattaataaa ggctataacc ctgacagagg aatgtggcag
    32761 cagagtgaag ggaaagcgta ctttaccggc gcaccaactc gcgctgcgct gaaagtgtca
    32821 ttctttggtc ctttctatgg cggttataac gttattgcac tcgatcggga ataccgccat
    32881 gcgctggttt gcggcccgga ccgcgactac ctgtggatac tctcccgcac gccaaccatt
    32941 tctgacgaag tgaaacagga gatgctggca gtcgcgaccc gggaagggtt tgatgtcagt
    33001 aaatttattt gggtacagca gcctggtagt tagtgagtgc tgagtttcag accaataatc
    33061 cccaatacga ttaacgccag actcgccagg cgcatcgggt tagcggactc accgagcagc
    33121 acaatgccgg ttatggccgc gccgactgcg ccaatacccg tccacacggc ataagccgtc
    33181 cctactggta acgatttcat cgcccaggca agtagcgcca tactgacaat catcgccgtc
    33241 acagtaataa cactcggcgt caaacgacta aagccgtggg tatatttcag gccaacggcc
    33301 cataccactt ccagcagacc agcaataact aagataatcc aggacatatc aggctccgga
    33361 gaattggggc cgtccccggt gaaaagaggc gtttgcaggt cgtcctgcaa agctgatggt
    33421 tgaacggata ttttgccagg tggcagggga atttcaacta ttacctttgt gactatcgca
    33481 gaaaaaacaa acggcacgac acagctgtcg taccgttatt gcttattgct gcgctttcgt
    33541 tgctgcgcca gaaatcgcgt taccgccatc agaaatgtct tcaccaacgc cacgcgtggt
    33601 gttgcaggca gttaatactg ttgaaagcac cagaacagaa aagatcgctg caattgtctt
    33661 cttcaccata acgtcttcct tttaggtaat gttatttatg tttgcctata gcaaattaat
    33721 aatagacaac atcgccaaaa atgatgggaa tctgatgatt tttcggaaga gaagaaaaat
    33781 tagctggcag cgcgagagat ggagttgccg agatgtttga tgtcttcgcc gaaaccgcga
    33841 gcggtgttac agcccgtgag cagcgtgctg gcaagcaaaa caagaacgat aaggcgtttc
    33901 atcatctctg acctgaataa gtgatggtgc agcctgcagg ccgcaccaca accgcattac
    33961 ttcacgcgag agacgtattc accagagcgg gtatccactt tgatgacttc gccgatttgt
    34021 acaaacagcg gaactttaac cacagcgcca gtagacaggg tagccggttt gccaccagta
    34081 cctgcggtat cacctttcag gcccggatcg gtatcaacga tttccagttc aacgaagttc
    34141 ggcggagtaa cggagatcgg ctgaccattc cacagagtta cgatgcactc tgcctgatcc
    34201 agcagccatt tagcgttgtc accaattgct tttgcatcag cagacagctg ctcgaaagtt
    34261 tcgttgttca tgaagtgcca gaactcaccg tcgttgtaca ggtaagtcag gttcatatcg
    34321 acaacatcag cgccttcagc ggaatcagta gatttgaagg ttttttctac gcgagtaccg
    34381 gtcagcagac gacgcagttt aacgcgagca aatgcctggc ctttacccgg ttttacgaat
    34441 tcactcgctt caaccgcgta aggttcgccg tctaacatga ttttaagacc agcacgaaaa
    34501 tcgttgctat agtacgttgc cataaggccc tctgaaattt gttaattggt agctaagcca
    34561 caaaatggcg catattgtaa ccctaaatac cccatccaga gaagattggt taacgcaact
    34621 tgccgatgtt gtgaccgatc ctgatgaact tctgcgtctt ttgaatatag acgcggagga
    34681 aaaactgtta gccggacgca gcgccaaaaa gctttttgcc ctgcgtgtgc cccgctcatt
    34741 tatcgatcgc atggagaaag gcaatccgga cgatcctctt ttgcgtcagg tacttacctc
    34801 gcaagatgag tttgtcatcg cgcccggatt ctccaccgac ccactggaag aacagcacag
    34861 cgtagtgcct ggtttgttgc ataaatacca caaccgggcg cttttgctgg tcaaaggcgg
    34921 ctgcgcggta aattgccgct attgcttccg tcgtcacttc ccctatgccg aaaatcaggg
    34981 caacaagcgt aactggcaaa ctgcacttga gtatgttgct gcgcatccgg aactggacga
    35041 gatgattttc tccggcggcg atccgctgat ggcgaaagat cacgagctgg actggttgct
    35101 cacacaactg gaagccatcc cgcatataaa acgtctgcgg attcacagcc gtctgccgat
    35161 tgtgatcccg gcacgtatca ccgaggcgct ggttgaatgc tttgcccgtt ctacgctgca
    35221 aatcttgctg gtgaatcaca tcaaccatgc caatgaggta gatgaaacat tccgtcaggc
    35281 gatggctaag ttgcgccggg taggcgttac tttgctgaac cagagcgttc tgttacgtga
    35341 tgtgaacgat aacgcacaaa cgctggcaaa cctgagtaat gcgttgttcg atgccggcgt
    35401 aatgccgtat tacctgcatg tgctcgataa agtacagggc gcggcgcatt ttatggtgag
    35461 tgatgacgaa gcacggcaga ttatgcgtga gttgctgaca ctggtgtcgg gatatctggt
    35521 gccgaaactg gcgcgagaaa ttggcggcga acccagcaaa acgccgctgg atctccagct
    35581 acgccagcag taactgatta aacagggaag ttaaacatta aaattgcctg attcgctacg
    35641 cttatcaggc ctacatcgtg cattgaaatt gaatggattt gcaatgaact gtaggccgga
    35701 taaggcgttt acgctgcatc cggcaagagc aacaaacgca agtacagcaa cctgtcatta
    35761 aactgggaag tttaatcttt gcccgttgca taacctttaa ttattcatat gcattgctgt
    35821 tgttactttt tatatagcta acaccaataa ttaacctttc ttttctgttt atatagagtg
    35881 agtacggcta tttatgt
//
LOCUS       DAPOAV010000045        35244 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.045, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000045 DAPOAV010000000
VERSION     DAPOAV010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 35244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35244
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.045"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(269..344)
                     /locus_tag="RN951_002469"
     tRNA            complement(269..344)
                     /locus_tag="RN951_002469"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(309..311),aa:Asn,seq:gtt)
     gene            complement(445..2088)
                     /gene="yeeO"
                     /locus_tag="RN951_002470"
                     /pseudo
     CDS             complement(445..2088)
                     /gene="yeeO"
                     /locus_tag="RN951_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416491.3"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toxic metabolite efflux MATE transporter YeeO"
     gene            2093..2168
                     /locus_tag="RN951_002471"
     tRNA            2093..2168
                     /locus_tag="RN951_002471"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2126..2128,aa:Asn,seq:gtt)
     gene            complement(2206..3156)
                     /gene="cbl"
                     /locus_tag="RN951_002472"
     CDS             complement(2206..3156)
                     /gene="cbl"
                     /locus_tag="RN951_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator Cbl"
                     /protein_id="HDX2527456.1"
                     /translation="MNFQQLKIIREAARQDYNLTEVANMLFTSQSGVSRHIRELEDEL
                     GIEIFVRRGKRLLGMTEPGKALLVIAERILNEASNVRRLADLFTNDTSGVLTIATTHT
                     QARYSLPEVIKAFRELFPEVRLELIQGTPQEIATLLQNGEADIGIASERLSNDPQLVA
                     FPWFRWHHSLLVPLDHPLTQITPLTLESIAKWPLITYRQGITGRSRIDDAFARKGLPA
                     DIVLSAQDSDVIKTYVALGLGIGLVAEQSSGEQEEENLIRLDTRHLFDTNTVWLGLKR
                     GQLQRNYVWRFLELCNAGLSVEDIKRQVMENSEEEIDYQI"
     gene            complement(3258..4175)
                     /gene="nac"
                     /locus_tag="RN951_002473"
     CDS             complement(3258..4175)
                     /gene="nac"
                     /locus_tag="RN951_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen assimilation transcriptional regulator
                     NAC"
                     /protein_id="HDX2527457.1"
                     /translation="MNFRRLKYFVKIVDIGSLTQAAEVLHIAQPALSQQVATLEGELN
                     QQLLIRTKRGVTPTDAGKILYTHARAILRQCEQAQLAVHNVGQALSGQVSIGFAPGTA
                     ASSITMPLLQAVRAEFPEIVIYLHENSGAVLNEKLINHQLDMAVIYEHSPVAGVSSQA
                     LLKEDLFLVGTQDCPGQSVDVNAIAQMNLFLPSDYSAIRLRVDEAFSLRRLTAKVIGE
                     IESIATLTAAIASGMGVAVLPESAARSLCGAVNGWMSRITTPSMSLSLSLNLPARANL
                     SPQAQAVKELLMSVISSPVMEKRQWQLVS"
     gene            4502..4577
                     /locus_tag="RN951_002474"
     tRNA            4502..4577
                     /locus_tag="RN951_002474"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4535..4537,aa:Asn,seq:gtt)
     gene            4739..6001
                     /locus_tag="RN951_002475"
     CDS             4739..6001
                     /locus_tag="RN951_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDX2527458.1"
                     /translation="MSLTDAKIRTLKPSDKPFKVSDSHGLYLLVKPGGSRHWYLKYRI
                     SGKESRIALGAYPAISLSDARQQREGIRKMLALNINPVQQRAAERGSRTPEKVFKNVA
                     LAWHKSNRKWSQNTADRLLASLNNHIFPVIGNLPVSELKPRHFIDLLKGIEEKGLLEV
                     ASRTRQHLSNIMRHAVHQELIDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGA
                     YHQGRELTRHAVLLMLHVFIRSSELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRG
                     AKMRMPHIVPLSEQSIAILKQIKDITGNNELIFPGDHNPYKPMSENTVNKALRVMGYD
                     TKKDICGHGFRAMACSALMESGLWAKDAVERQMSHQERNTVRMAYIHKAEHLEARKAM
                     MQWWSDYLEACRESYAPPYTIGKNKFIP"
     gene            complement(6195..7499)
                     /gene="ybtS"
                     /locus_tag="RN951_002476"
     CDS             complement(6195..7499)
                     /gene="ybtS"
                     /locus_tag="RN951_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin biosynthesis salicylate synthase
                     YbtS"
                     /protein_id="HDX2527459.1"
                     /translation="MKISEFLHLALPEEQWLPTISGVLRQFAEEECYVYERQPCWYLG
                     KGCQARLHINADGTQATFIDDAGEQKWAVDSIADCARRFMAHPQVKGRRVYGQVGFNF
                     AAHARGIAFNAGEWPLLTLTVPREELIFEKGNVTVYADSADGCRRLCEWVKEAGTTTQ
                     NAPLAVDTALNGEAYKQQVARAVAEIRRGEYVKVIVSRAIPLPSRIDMPATLLYGRQA
                     NTPVRSFMFRQEGREALGFSPELVMSVTGNKVVTEPLAGTRDRMGNPEHNKAKEAELL
                     HDSKEVLEHILSVKEAIAELEAVCQPGSVVVEDLMSVRQRGSVQHLGSGVSGQLAENK
                     DAWDAFTVLFPSITASGIPKNAALNAIMQIEKTPRELYSGAILLLDDTRFDAALVLRS
                     VFQDSQRCWIQAGAGIIAQSTPERELTETREKLASIAPYLMV"
     gene            complement(7527..8807)
                     /gene="ybtX"
                     /locus_tag="RN951_002477"
     CDS             complement(7527..8807)
                     /gene="ybtX"
                     /locus_tag="RN951_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin-associated zinc MFS transporter
                     YbtX"
                     /protein_id="HDX2527460.1"
                     /translation="MSDVQSNVKPLTLTTGRVIFAIAGVYVTQSLVSALSMQSLPALV
                     RAAGGSLALAGATTLFMLPWALKFIWAPWIERWRLPPGSQERRSRMLILRGQVALAAI
                     LTIAAAIGWFGREGGFPDTQIVALFVLFMVAGTVASTIDIASDGFCVDQLTRTGYGWG
                     NSVQVGGSYLGMMCGGGVFLMLSAASGWPVAMLMMAVLIMALSLPLWRITEPTRTATI
                     PHVPALGYALRRKQARLGLLLVLMLNSGMRFVLPLLAPLLLDHGLSMSALGALFSGGN
                     IAAGIAGTLAGGLLMKYTSPGRALLTAYGVQGIALLAVVMTLMMAPGHLLLPILQCLV
                     IVQSISLACALVCLYATLMSLSSPLQAGVDFTLFQCTDAAIAILAGVIGGVVAQHFGY
                     AACFLFAGAFTLLAAWVAYIRLHSARELMTSAID"
     gene            complement(8800..10602)
                     /gene="ybtQ"
                     /locus_tag="RN951_002478"
     CDS             complement(8800..10602)
                     /gene="ybtQ"
                     /locus_tag="RN951_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin ABC transporter
                     ATP-binding/permease protein YbtQ"
                     /protein_id="HDX2527461.1"
                     /translation="MKDNNPADNLAWRVIWRQLISSVGSQARMLRRSMLALLLAAFMQ
                     GIAFACLYPIIDALLRGDAPQLLNWAMAFSVAAIVTLVLRWYGLGFEYRGHLAQATHE
                     LRLRLGEQLRRVPLEKLQRGRAGEMNALLLGNVDENLNYVIAIANILLLTIVTPLTAS
                     LATLWIDWRLGLVMLLIFPLLVPFYYWRRPAMRRQMQTLGEAHQRLSGDIVEFAQGMM
                     VLRTCGSDADKSRALLAHFNALENLQTRTHRQGAGATMLIASVVELGLQVVVLSGIVW
                     VVTGTLNLAFLIAAVAMIMRFAEPMAMFISYTSVVELIASALQRIERFMAIAPLPVAE
                     QSEMPERYDIRFDNVSYRYEEGDGHALNHVSLTFPAASMSALVGASGAGKTTVTKLLM
                     RYADPQQGQISIGGVDIRRLTPEQLNSLISVVFQDVWLFDDTLLANIRIARPQATRQE
                     VEEAARAAQCLEFISRLPQGWLTPMGEMGGQLSGGERQRISIARALLKNAPVVILDEP
                     TAALDIESELAVQKAIDNLVHNRTVIIIAHRLSTIAGAGNILVMEEGQVVEQGTHAQL
                     LSHHGRYQALWQAQMAARVWRDDGVSASGEWVHE"
     gene            complement(10589..12301)
                     /gene="ybtP"
                     /locus_tag="RN951_002479"
     CDS             complement(10589..12301)
                     /gene="ybtP"
                     /locus_tag="RN951_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin ABC transporter
                     ATP-binding/permease protein YbtP"
                     /protein_id="HDX2527462.1"
                     /translation="MALAGLAALTSLGALLFLAWSLRDIRATPDAIPAWPLGGVIGCV
                     VLTFVLRLQAFNTSHYAAFHLENILRSRLARKALQLPPGVLQQMGSGSVAKVMLDDVK
                     SLHIFVADSTPLYARAIIMPLATIVILFWLDWRLAIATLGVLAFGSVVLVLARQRSED
                     MAQRYHKAREQVSAAVIEFVQAMPVVRTFDSGSTSFLRYQRALEEWVDVLKTWYRKAG
                     FSARFSFSILNPLPTLFVLIWSGYGLLHYGSFDFIAWVAVLLLGSGMAEAVMPMMMLN
                     NLVAQTRLSIQRIYQVLAMPELSLPQSDQQPQEASITFEQVSFHYPQARTGAALQEVS
                     FHVPAGQIVALVGPSGAGKSTVARLLLRYADPDKGHIRIGGVDLRDMQTDTLMKQLSF
                     VFQDNFLFADTIANNIRLGAPDTPLEAVIAAARVAQAHDFISALPEGYNTRVGERGVF
                     LSGGQRQRITIARALLQDRPILVLDEATAFADPENEAALIKALAAAMRGRTVIMVAHR
                     LSMVTQADVILLFSDGQLREMGNHTQLLAQGGLYQRLWQHYQQAQHWVPGGTQEEVVE
                     NERQ"
     gene            12558..13517
                     /gene="ybtA"
                     /locus_tag="RN951_002480"
     CDS             12558..13517
                     /gene="ybtA"
                     /locus_tag="RN951_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin transcriptional regulator YbtA"
                     /protein_id="HDX2527463.1"
                     /translation="MTESPQTQSEISIHQLVVGKPANDGNIPAQCELLRCSLQEGMDI
                     LLWRGHFARPETLQLHDDLGRINFSCILEGTSRFAIQGLRRHTDWELARNRHYITHTP
                     DCRGSASYCGRFESITLSFSPETLALWVPDISAVIKNKIDSHCCCQQQRCNAETHLTA
                     QALRHALMRMHGGFSHEQKPSTLWLQGQSLVMLSLVLDEHREDASCLSCHFNPMERQK
                     LLRAKDLLLADLTQAPGVAELARESGLSVLKIKRGFRVLFNNSVYGLFQAERMQEARR
                     RLANGNTSVMTVAADLGYANASHFSAAFQKQFGVTPSTFKRVM"
     gene            13708..19815
                     /gene="irp2"
                     /locus_tag="RN951_002481"
     CDS             13708..19815
                     /gene="irp2"
                     /locus_tag="RN951_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin non-ribosomal peptide synthetase
                     HMWP2"
                     /protein_id="HDX2527464.1"
                     /translation="MISGAPSQDSLLPDNRHAADYQQLRERLIQELNLTPQQLHEESN
                     LIQAGLDSIRLMRWLHWFRKNGYRLTLRELYAAPTLAAWNQLMLSRSPENAEEETPPD
                     ESSWPNMTESTPFPLTPVQHAYLTGRMPGQTLGGVGCHLYQEFEGHCLTASQLEQAIT
                     TLLQRHPMLHIAFRPDGQQVWLPQPYWNGVTVHDLRHNDAESRQAYLDALRQRLSHRL
                     LRVEIGETFDFQLTLLPDNRHRLHVNIDLLIMDASSFTLFFDELNALLAGESLPAIDT
                     RYDFRSYLLHQQKINQTLRDDARAYWLAKASTLPPAPVLPLACEPATLREVRNTRRRM
                     IVPATRWHAFSNRAGEYGVTPTMALATCFSAVLARWGGLTRLLLNITLFDRQPLHPAV
                     GAMLADFTNILLLDTACDGDTVSNLARKNQLTFTEDWEHRHWSGVELLRELKRQQRYP
                     HGAPVVFTSNLGRSLYSSRAESPLGEPEWGISQTPQVWIDHLAFEHHGEVWLQWDSND
                     ALFPPALVETLFDAYCQLINQLCDDESAWQKPFADMMPASQRAIRERVNATGAPIPEG
                     LLHEGIFRIALQQPQALAVTDMRYQWNYHELTDYARRCAGRLIECGVQPGDNVAITMS
                     KGAGQLVAVLAVLLAGAVYVPVSLDQPAARREKIYADASVRLVLICQHDTSAGSDDIP
                     VLAWQQAIEAEPIANPVVRAPTQPAYIIYTSGSTGTPKGVVISHRGALNTCCDINTRY
                     QVGPHDRVLALSALHFDLSVYDIFGVLRAGGALVMVMENQRRDPHAWCELIQRHQVTL
                     WNSVPALFDMLLTWCEGFADATPENLRAVMLSGDWIGLDLPARYRAFRPQGQFIAMGG
                     ATEASIWSNACEIHDVPAHWRSIPYGFPLTNQRYRVVDEQGRDCPDWVPGELWIGGIG
                     VAEGYFNDPLRSEQQFLTLPDERWYRTGDLGCYWPDGTIEFLGRRDKQVKVGGYRIEL
                     GEIESALSQLAGVKQATVLAIGEKEKTLAAYVVPQGEAFCVTDHRNPALPQAWHTLAG
                     TLPCCAISPEISAEQVADFLQHRLLKLKPGHTAGADPLPLMNSLAIQPRWQAVVELWL
                     AFLVTQRRLKPAAEGYQVCAGEEHEDEHPHFSGHDLTLSQILRGARNELSLLNDAQWS
                     PESLAFNHPASAPYIQELATICQQLAQRLQRPVRLLDVGTRTGRAAESLLAQLNAGQI
                     EYVGLEQSQEMLLSARQRLAPWPGARLSLWNADTLAAHAHSADIIWLNNALHRLLPED
                     PGLLATLQQLAVPGALLYVMEFRQLTPSALLSTLLLTNGQPEALLHNSADWAALFSAA
                     AFNCQHGDEVAGLQRFLVQCPDRQVRRDPRQLQAALAGRLPGWMVPQRIVFLDALPLT
                     ANGKIDYQALKRRHTPEAENPAEADLPQGDIEKQVAALWQQLLSTGNVTRETDFFQQG
                     GDSLLATRLTGQLHQAGYEAQLSDLFNHPRLADFAATLRKTDVPVEQPFVHSPEERYQ
                     PFALTDVQQAYLVGRQPGFALGGVGSHFFVEFEIADLDLTRLETVWNRLIARHDMLRA
                     IVRDGQQQVLEQTPPWVIPTHTLHTPEEALRVREKLAHQVLNPEVWPVFDLQVGYVDG
                     MPARLWLCLDNLLLDGLSMQILLAELEHGYRYPQQLLPPLPVTFRDYLQQPSLQSPNP
                     DSLAWWQAQLDDIPPAPALPLRCLPQEVETPRFARLNGALDSTRWHRLKKRAADAHLT
                     PSAVLLSVWSTVLSAWSAQPEFTLNLTLFDRRPLHPQINQILGDFTSLMLLSWHPGES
                     WLHSAQSLQQRLSQNLNHRDVSAIRVMRQLAQRQNVPAVPMPVVFTSALGFEQDNFLA
                     RRNLLKPVWGISQTPQVWLDHQIYESEGELRFNWDFVAALFPAGQVERQFEQHCALLN
                     RMAEDESGWQLPLAALVPPVKHAGQCAERSPRVCPEHSQPHIAADESTVSLICDAFRE
                     VVGESVTPAENFFEAGATSLNLVQLHVLLQRHEFSTLTLLDLFTHPSPAALADYLAGV
                     ATVEKTKRPRPVRRRQRRI"
     gene            19903..29394
                     /gene="irp1"
                     /locus_tag="RN951_002482"
     CDS             19903..29394
                     /gene="irp1"
                     /locus_tag="RN951_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin polyketide synthase HMWP1"
                     /protein_id="HDX2527465.1"
                     /translation="MDNLRFSSAPTADSIDASIAQHYPDCEPVAVIGYACHFPESPDG
                     ETFWQNLLEGRECSRRFTREELLAVGLDAAIIDDPHYVNIGTVLDNADCFDATLFGYS
                     RQEAESMDPQQRLFLQAVWHALEHAGYAPGAVPHKTGVFASSRMSTYPGREALNVTEV
                     AQVKGLQSLMGNDKDYIATRAAYKLNLHGPALSVQTACSSSLVAVHLACESLRAGESD
                     MAVAGGVALSFPQQAGYRYQPGMIFSPDGHCRPFDASAEGTWAGNGLGCVVLRRLRDA
                     LLSGDPIISVILSSAVNNDGNRKVGYTAPSVAGQQAVIEEALMLAAIDDRQVGYIETH
                     GTGTPLGDAIEIEALRNVYAPRPQDQRCALGSVKSNMGHLDTAAGIAGLLKTVLAVSR
                     GQIPPLLNFHTPNPALKLEESPFTIPVSAQAWQDEMRYAGVSSFGIGGTNCHMIVASL
                     PDALNARLPDTDSGRKSTALLLSAASDSALRRLATDYAGALREDADASSLAFTALHAR
                     RLDLPFRLAAPLNRETAEALSAWAGEKSGALVYSGHGASGKQVWLFTGQGSHWRTMGQ
                     TMYQHSTAFADTLDRCFSACSEMLTPSLREAMFNPDSAQLDNMAWAQPAIVAFEIAMA
                     AHWRAEGLKPDFAIGHSVGEFAAAVVCGHYTIEQVMPLVCRRGALMQQCASGAMVAVF
                     ADEDTLMPLARQFELDLAANNGTQHTVFSGPEARLAVFCATLSQHDINYRRLSVTGAA
                     HSALLEPILDRFQDACAGLHAEPGQIPIISTLTADVIDESTLNQADYWRRHMRQPVRF
                     IQSIQVAHQLGARVFLEMGPDAQLVACGQREYRDNAYWIASARRNKEASDVLNQALLQ
                     LYAAGVALPWADLLAGDGQRIAAPCYPFDTERYWKERVSPACEPADAALSAGLEVASR
                     AATALDLPRLEALKQCATRLHAIYVDQLVQRCTGDAIENGVDAMTIMRRGRLLPRYQQ
                     LLQRLLNNCVVDGDYRCTDGRYVRARPIEHQQRESLLTELAGYCEGFQAIPDTIARAG
                     DRLYEMMSGAEEPVAIIFPQSASDGVEVLYQEFSFGRYFNQIAAGVLRGIVQTRQPRQ
                     PLRILEVGGGTGGTTAWLLPELNGVPALEYHFTDISALFTRRAQQKFADYDFVKYSEL
                     DLEKEAQSQGFQAQSYDLIVAANVIHATRHIGRTLDNLRPLLKPGGRLLMREITQPMR
                     LFDFVFGPLVLPLQDLDAREGELFLTTAQWQQQCRHAGFSKVAWLPQDGSPTAGMSEH
                     IILATLPGQAVSAVTFTAPSEPVLGQALTDNGDYLADWSDCAGQPERFNARWQEAWRL
                     LSQRHGDALPVEPPPVAAPEWLGKVRLSWQNEAFSRGQMRVEARHPAGEWLPLSPAAP
                     LPAPQTHYQWRWTPLNVASIDHPLTFSFSAGTLARSDELAQYGIIHDPHASSRLMIVE
                     ESEDTLALAEKVIAALTASAAGLIVVTRRAWRVEENEALSASHHALWALLRVAANEQP
                     ERLLAAIDLAENTPWETLHQGLSAVSLSQRWLAARGDTLWLPSLAPNTGCAAELPANV
                     FTGDSRWHLVTGAFGGLGRLAVNWLREKGARRIALLAPRVDESWLRDVEGGQTRVCRC
                     DVGDAGQLATVLDDLAANGGIAGAIHAAGVLADAPLQELDDHQLAAVFAVKAQAASQL
                     LQTLRNHDGRYLILYSSAAATLGAPGQSAHALACGYLDGLAQQFSTLDAPKTLSVAWG
                     AWGESGRAATPEMLATLASRGMGALSDAEGCWHLEQAVMRGAPWRLAMRVFTDKMPPL
                     QQALFNISATEKAATPVIPPADDNAFNGSLSDETAVMAWLKKRIAVQLRLSDPASLHP
                     NQDLLQLGMDSLLFLELSSDIQHYLGVRINAERAWQDLSPHGLTQLICSKPEATPAAS
                     QPEVLRHDADERYAPFPLTPIQHAYWLGRTHLIGYGGVACHVLFEWDKRHDEFNLAIL
                     EKAWNQLIARHDMLRMVVDADGQQRILATTPEYHIPRDDLRALSPEEQRIALEKRRHE
                     LSYRVLPADQWPLFELVVSEIDDCHYRLHMNLDLLQFDVQSFKVMMDDLAQVWRGETL
                     APLAITFRDYVMAEQARRQTSAWHDAWDYWQEKLPQLPLAPELPVVETPPETPHFTTF
                     KSTIGKTEWQAVKQSWQQQGVTPSAALLTLFAATLERWSRTTTFTLNLTFFNRQPIHP
                     QINQLIGDFTSVTLVDFNFSAPVTLQEQMQQTQQRLWQNMAHSEMNGVEVIRELGRLR
                     GSQRQPLMPVVFTSMLGMTLEGMTIDQAMSHLFGEPCYVFTQTPQVWLDHQVMESDGE
                     LMFSWYCMDNVLEPGAAEAMFNDYCAILQAVIAAPESLKTLASGIAGHIPRRRWPLNA
                     QADYDLRDIEQATLEYPGIRQARAEITEQGALTLDIVMADDPSPSAAMPDEHELTQLA
                     LPLPEQAQLDELEATWRWLEARALQGIAATLNRHGLFTTPEIAHRFSAIVQALSAQAS
                     HQRLLRQWLQCLTEREWLIREGESWRCRIPLSEIPEPQEACPQSQWSQALAQYLETCI
                     ARHDALFSGQCSPLELLFNEQHRVTDALYRDNPASACLNRYTAQIAALCSAERILEVG
                     AGTAATTAPVLKATRNTRQSYHFTDVSAQFLNDARARFHDESQVSYALFDINQPLDFT
                     AHPEAGYDLIVAVNVLHDASHVVQTLRRLKLLLKAGGRLMIVEATERNSVFQLASVGF
                     IEGLSGYRDFRRRDEKPMLTRSAWQEVLVQAGFANELAWPAQESSPLRQHLLVARSPG
                     VNRPDKKAVSRYLQQRFGTGLPILQIRQREALFTPLHAPSDAPTEPAKPTPVAGGNPA
                     LEKQVAELWQSLLSRPVARHHDFFELGGDSLMATRMVAQLNRRGIARANLQDLFSHST
                     LSDFCAHLQAATSGEDNPIPLCQGDGEETLFVFHASDGDISAWLPLASALNRRVFGLQ
                     AKSPQRFATLDQMIDEYVGCIRRQQPHGPYVLAGWSYGAFLAAGAAQRLYAKGEQVRM
                     VLIDPVCRQDFCCENRAALLRLLAEGQTPLALPEHFDQQTPDSQLADFISLAKTAGMV
                     PQNLTLQAAETWLDNIAHLLRLLTEHTPGESVPVPCLMVYAAGRPARWTPAETEWQGW
                     INNADDAVIEASHWQIMMEAPHVQACAQHITRWLCATSTQPENTL"
     gene            29391..30491
                     /gene="ybtU"
                     /locus_tag="RN951_002483"
     CDS             29391..30491
                     /gene="ybtU"
                     /locus_tag="RN951_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin biosynthesis oxidoreductase YbtU"
                     /protein_id="HDX2527466.1"
                     /translation="MMPSASPKQRVLIVGAKFGEMYLNAFMQPPEGLELVGLLAQGSA
                     RSRELAHAFGIPLYTSPEQITRMPDIACIVVRSTVAGGTGTQLARHFLTRGVHVIQEH
                     PLHPDDISSLQTLAQEQGCCYWVNTFYPHTRAGRTWLRDAQQLRRCLAKTPPVVHATT
                     SRQLLYSTLDLLLLALGVDAAAVECDVVGSFSDFHCLRLFWPEGEACLLLQRYLDPDD
                     PDMHSLIMHRLLLGWPEGHLSLEASYGPVIWSSSLFVADHQENAHSLYRRPEILRDLP
                     GLTRSAAPLSWRDCCETVGPEGVSWLLHQLRSHLAGEHPPAACQSVHQIALSRLWQQI
                     LRKTGNAEIRRLTPPHHDRLAGFYNDDDKEAL"
     gene            30488..31291
                     /gene="ybtT"
                     /locus_tag="RN951_002484"
     CDS             30488..31291
                     /gene="ybtT"
                     /locus_tag="RN951_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin biosynthesis thioesterase YbtT"
                     /protein_id="HDX2527467.1"
                     /translation="MTQSAMCIPLWPARNGNTAHLVMCPFAGGSSSAFRHWQAEQLAD
                     CALSLVTWPGRDRLRHLEPLRSITQLAALLANELEASVSPDTPLLLAGHSMGAQVAFE
                     TCRLLEQRGLAPQGLIISGCHAPHLHSERQLSHRDDADFIAELIDIGGCSPELRENQE
                     LMSLFLPLLRADFYATESYHYDSPDVCPPLRTPALLLCGSHDREASWQQVDAWRQWLS
                     PVTGPVVIDGDHFYPIQQARSFFTQIVRHFPHAFSAMTALQKQPSTSER"
     gene            31295..32872
                     /gene="ybtE"
                     /locus_tag="RN951_002485"
     CDS             31295..32872
                     /gene="ybtE"
                     /locus_tag="RN951_002485"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin biosynthesis salycil-AMP ligase
                     YbtE"
                     /protein_id="HDX2527468.1"
                     /translation="MNSSFESLIEQYPLPIAEQLRHWAARYASRIAVVDAKGSLTYSA
                     LDAQVDELAAGLSSLGLRSGEHVIVQLPNDNAFVTLLFALLRLGVIPVLAMPSQRALD
                     IDALIELAQPVAYVIHGENHAELARQMAHKHACLRHVLVAGETVSDDFTPLFSLHGER
                     QAWPQPDVSATALLLLSGGTTGTPKLIPRRHADYSYNFSASAELCGISQQSVYLAVLP
                     VAHNFPLACPGILGTLACGGKVVLTDSASCDEVMPLIAQERVTHVALVPALAQLWVQA
                     REWEDSDLSSLRVIQAGGARLDPTLAEQVIATFDCTLQQVFGMAEGLLCFTRLDDPHA
                     TILHSQGRPLSPLDEIRIVDQDENDVAPGETGQLLTRGPYTISGYYRAPAHNAQAFTA
                     QGFYRTGDNVRLDEVGNLHVEGRIKEQINRAGEKIAAAEVESALLRLAEVQDCAVVAA
                     PDTLLGERICAFIIAQQVPTDYQQLRQQLTRMGLSAWKIPDQIEFLDHWPLTAVGKID
                     KKRLTALAVDRYRHSAQ"
     gene            33003..35024
                     /gene="fyuA"
                     /locus_tag="RN951_002486"
     CDS             33003..35024
                     /gene="fyuA"
                     /locus_tag="RN951_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore yersiniabactin receptor FyuA"
                     /protein_id="HDX2527469.1"
                     /translation="MKMTRLYPLALGGLLLPAIANAQTSQQDESTLVVTASKQSSRSA
                     SANNVSSTVVSAPELSDAGVTASDKLPRVLPGLNIENSGNMLFSTISLRGVSSAQDFY
                     NPAVTLYVDGVPQLSTNTIQALTDVQSVELLRGPQGTLYGKSAQGGIINIVTQQPDST
                     PRGYIEGGVSSRDSYRSKFNLSGPIQDGLLYGSVTLLRQVDDGDMINPATGSDDLGGT
                     RASIGNVKLRLAPDDQPWEMGFAASRECTRATQDAYVGWNDIKGRKLSISDGSPDPYM
                     RRCTDSQTLSGKYTTDDWVFNLISAWQQQHYSRTFPSGSLIVNIPQRWNQDVQELRAA
                     TLGDARTVDMVFGLYRQNTREKLNSAYDMPTMPYLSSTGYTTAETLAAYSDLTWHLTD
                     RFDIGGGVRFSHDKSSTQYHGSMLGNPFGDQGKSNDDQVLGQLSAGYMLTDDWRVYTR
                     VAQGYKPSGYNIVPTAGLDAKPFVAEKSINYELGTRYETADVTLQAATFYTHTKDMQL
                     YSGPVGMQTLSNAGKADATGVELEAKWRFAPGWSWDINGNVIRSEFTNDSELYHGNRV
                     PFVPRYGAGSSVNGVIDTRYGALMPRLAVNLVGPHYFDGDNQLRQGTYATLDSSLGWQ
                     ATERMNISVYVDNLFDRRYRTYGYMNGSSAVAQVNMGRTVGINTRIDFF"
BASE COUNT         7834 a        10522 c         9536 g         7352 t
ORIGIN      
        1 ttcccgataa agatgcgaca gctacatccc gcataaggca tttttctctt tatctttgta
       61 cggtacttca tggaacagaa tttttgacct tgtgaatcgt gatgtctgtt ggggaggggc
      121 aatttgctca ctgaagcgtg agactcgatt aagcgcacga aacacagaaa tcaaaaacca
      181 ggccactctt ttacaaagtg gccgggtaaa aataattttt attttttaac tgtcctgaga
      241 ctcatagaga tgtctcaaaa ctaaaatttg gctcctctga ctggactcga accagtgaca
      301 tacggattaa cagtccgccg ttctaccgac tgaactacag aggaatcgtg agaacgaggc
      361 gaatattagc gatgcccacc cacaatgtca aagcctgttt tttaaatttg aaatcgtttg
      421 ctgaaataat ctgcattttg tcgtttattc cgacacaact ggcttttttt cacacttttg
      481 cggctcggat cgagggtatt tccacagcca acgtccagta accattcgcc agtaaaacag
      541 cacggcccgc acagcccagt cggcaaacat tcccatccag acaccaacca caccccagcc
      601 aagcatgatt cccagcacat aaccgactac aacccggcaa ccccacatgc tcaacataga
      661 aacccacatg gcgtaacggg catcacgagc ccccttaaat ccagcgggta gcacccatga
      721 ggcggaccaa ataggcataa ataaagcatt tagccaaatc agaatcacaa cgacgtgttt
      781 aacctgtgga tcctgggtgt aaaacgatgc cataaccccg gcaaagggag ccgttagcca
      841 ggcgatggcc gttaatccaa gagtggacag ccagaacaca tgccgcaact gaatctctgc
      901 ttgcgctatc taccctaccc ccaaccttcg gcctgtaatg atcgtagaag cagaaccgag
      961 cgcacttccg ggtaagttga taagagccgc aattgagaac gcgataaaat ttccggcaat
     1021 aacgctggtc cccatcacgg caacgaacat ttgggttaat aaccgaccac tggtaaataa
     1081 cactgattcg acactcgctg gaataccaat ccccatgact tcccagataa tgctaaaatt
     1141 cagcagttta aaatagctct ttaacgaaat ccttagcgca ggattaaaac caatcgccag
     1201 cacccacaaa attgcaactg cgccaatata acgagaaatg gttaaaccca acccagcccc
     1261 gacaaatccc agtcccggcc aggagaaaag gccgtaaatc aatatgccgc taataataat
     1321 attaagaata ttcaggctac cgttaatcag tagcggtatt ttcgtattcc ctgcaccacg
     1381 aagtgccccg ctaccaataa gagtgatggc agctgctgga taactgagta cggtcagctc
     1441 cagataagtc aacgccagtg ctttaacttc tgtcgtggca tcacccgcga cgaaatcaat
     1501 aatttgttcg ccaaaatgat gaattagcgt tgccaacagt acggcaaaca acgtcatgat
     1561 caccaatgac tgccgcgtcg ccaccctcgc tcgtcgtcga tcccgcttac cgagactaaa
     1621 tgccacaacg acagtagtac caagatcgat agctgcaaaa aaagccataa tgaccatatt
     1681 gaagctgtcc gccaatccca cgccggccat cgcatctttt cccagccagc tgaccagaaa
     1741 agtgctcagg acccccatca acaggacaca ggcgttctcc atgaagatag gaacagcaag
     1801 cggggttatc tcgcgccaga acaacacttt gtagctcttg cgtttagcgt gccagcgagt
     1861 gccgtgaaca acctggcgta aagcagagga gatattcaaa gccgacctta attgcagaaa
     1921 gtgaaaccac atttcaaatg atgagggaga atcagcaaag ctgcaaagat tttcgccaac
     1981 aaattgtctg caaatgcaac aaactgttga tagaaacggc aaacagttgg gaaatttaaa
     2041 aatcgggttt gacaaaatat ttttcgccgt taagatgtgc ctcaacagcg attcctctgt
     2101 agttcagtcg gtagaacggc ggactgttaa tccgtatgtc actggttcga gtccagtcag
     2161 aggagccaaa tttctgaaaa gcccgctttt atagcgggct ttttgctata tctgataatc
     2221 aatttcctct tcactgtttt ccatcacctg gcgcttgata tcctcaactg acagtcctgc
     2281 attacaaagt tccagaaagc gccagacata gttacgctga agttgtcctc gcttcagtcc
     2341 caaccagaca gtattagtat cgaaaagatg ccgcgtatcc aggcggatta aattctcttc
     2401 ctcttgttcg ccgctggatt gttcggcaac taatccgatc ccaagcccaa gagcaacata
     2461 ggttttaatg acatcagaat cctgtgcact taatacaata tctgccggca aacctttgcg
     2521 ggcaaatgcg tcatcaatgc gtgagcgccc cgtaatcccc tgtcggtaag taattaacgg
     2581 ccacttcgct attgattcca gcgtcaacgg tgtaatttgc gtcaagggat gatcgagtgg
     2641 aacaagcaaa ctatggtgcc aacgaaacca cgggaaggcg acgagctgcg ggtcattact
     2701 caaacgctcg ctggcgatac caatatcagc ttcgccattt tgcaacaacg tcgcaatttc
     2761 ctgtggtgta ccctggatta gctccagccg aacctccggg aaaagttcgc gaaaagcttt
     2821 aatgacctct ggcaagctat aacgtgcctg agtatgcgtc gttgcaatag tgagaacgcc
     2881 agacgtatcg ttggtaaaca ggtctgcaag ccgacgaaca ttactggctt cattcagaat
     2941 acgttctgca atgaccagta atgctttgcc cggttcagtc atgcccagca gtcgcttacc
     3001 tcgtcgaaca aatatttcga tgccaagttc atcctccagt tcccgaatat gacggctgac
     3061 gcctgactgt gaggtaaaaa gcatattcgc aacctctgtc aggttgtaat cctgacgtgc
     3121 agcctcgcgg attatcttta gttgttggaa attcacggta aactccgggc agttcagatt
     3181 tcccgttatt gttaaagtct aatgcccggc ataacaaata ataaaaaccc gcatcttatt
     3241 ccatcccgat ataacactta gctcaccaat tgccactgcc ttttttccat cactggagaa
     3301 ctaatcactg acattaacaa ctctttcact gcctgtgcct gtggcgataa gttcgctctg
     3361 gcgggtaaat ttaatgacaa agagagactc atggaaggag tggtaatgcg tgacatccac
     3421 ccatttactg cgccacataa cgaacgcgcg gccgattcgg gtaatactgc aacgcccatg
     3481 ccgctggcaa tcgctgcggt aagcgtggca atagactcaa tttcaccaat aacttttgcc
     3541 gtgagtcgcc gtagggaaaa agcctcatca acacgaagtc taatagcact gtaatcactg
     3601 gggagaaaga ggttcatttg cgcaatagca ttcacatcaa cgctttgccc cgggcaatct
     3661 tgagttccta ccagaaaaag atcttctttc agcaaagcct gactggatac accagccaca
     3721 ggggaatgct cataaatcac cgccatatcg agttggtgat ttatcaattt ttcgttaagc
     3781 actgcaccac tattttcatg aagatagata acgatctccg gaaattcagc gcgaaccgcc
     3841 tgtaataagg gcatggtgat ggatgacgca gcggttcctg gtgcaaagcc aatcgagact
     3901 tgccccgata atgcctgacc aacgttatgc accgccagtt gggcctgttc acactgacgt
     3961 aaaatggccc gcgcatgggt atagagaatt tttccggcgt ctgttggtgt aacgccccgc
     4021 tttgtacgga tcaaaagttg ttgatttaac tcaccttcca gtgtggcaac ctgctggctg
     4081 agcgctggtt gtgcgatatg caatacttca gcagcctggg tcaggctacc aatatctaca
     4141 atttttacga agtatttcag gcgtctgaag ttcatgttgc ctccggtttt taagaatcgg
     4201 cccaagtgcc gccattactt acaaccagat tgcaagatgc ttgccagttt tattttggtg
     4261 ttgatgtaca agctaaccaa ctgtcaaata agagattatg atagattcgt catttgctcc
     4321 tttaatcagc tgtcgcgttc ccctgcccta taaaaggagg gtatgcacca cgatggttca
     4381 ttacccaata agattgaaag ctcaccactt tgttgaaatt gacagcaaac aaacaaaaaa
     4441 atgcatttca ccctttgaca tcaccatgta ctgccattaa tatgcgcccc gttcacacga
     4501 ttcctctgta gttcagtcgg tagaacggcg gactgttaat ccgtatgtca ctggttcgag
     4561 tccagtcaga ggagccaatt ttctgttttc atgcatcctt gcgaatcttt atctgatgtt
     4621 gattcaacag gttagtgtga aaactcttct cggtgcattt tgattttacc ctacgcatcg
     4681 ggaaaaattg gtggtcaaat ctggggtcag gttagttcga taatggagtg acccccatat
     4741 gtcccttacc gacgcaaaaa tccgcaccct caagccttct gataaaccct ttaaagtctc
     4801 cgattctcac ggtctgtatc tgctggttaa gccgggtggc tcccgccact ggtatctcaa
     4861 ataccgtatt agcggtaaag aatcccgcat tgcgctgggt gcctatccag ccatctccct
     4921 gtctgatgcg cgacagcaac gtgaaggtat ccgtaaaatg ctggcgctga atatcaaccc
     4981 ggtacagcag cgggctgctg aacgtggctc acgaacaccg gagaaagttt ttaaaaacgt
     5041 ggcgctggcg tggcataaaa gtaacaggaa atggtcgcag aacaccgccg accgtctgct
     5101 tgccagcctg aacaatcaca tctttccggt catcgggaac ctacctgtat cagaacttaa
     5161 accccgtcat ttcattgacc tgctgaaagg gatcgaggaa aaaggtctgc tggaggttgc
     5221 gtcccgcaca cggcagcacc tgagtaacat aatgcgccat gcggtccatc aggagttaat
     5281 cgatacgaac cctgcagcaa accttggcgg cgtgaccaca cctcctgtca gacggcacta
     5341 tcctgccctg ccgctggagc ggctgcctga actgcttgaa cgtattgggg catatcatca
     5401 gggccgtgaa ctgacccggc atgccgttct gctgatgctg catgtgttca ttcgctccag
     5461 tgaactgcgt ttcgcccgct ggtcagagat tgatttcaca aaccgagtct ggacgatacc
     5521 cgcgacgcga gaacccatta ttggcgtgcg ttattccggc cgcggggcaa aaatgcgaat
     5581 gccgcatatc gtccccctct cagaacagtc catcgccatt ctgaaacaga ttaaggatat
     5641 caccggtaat aatgaactga tcttccccgg cgaccataac ccgtataagc caatgtctga
     5701 aaacacggtc aataaggcac tgcgggtgat gggttacgac acgaaaaagg atatctgcgg
     5761 tcacggcttc cgggcaatgg catgcagtgc gctgatggaa tcgggtttat gggcaaagga
     5821 cgcagtagaa cgccagatga gtcatcagga gcgcaatacc gtgcgcatgg cttatattca
     5881 taaggcagag cacctagaag cccgcaaagc gatgatgcag tggtggtcgg attatctgga
     5941 agcatgccga gaatcttatg caccgcctta tacaattggt aaaaataagt ttatcccata
     6001 atatactaac gaatcccaca ctctggcaaa ttaccaccac ctccacagga ggtggttcta
     6061 tatagacttt tatcaacttc atgacgaaaa acacctattt tatcccaaaa gaagacaata
     6121 gagtcacaga ggaatcaaag agcgactcaa ttgtctttgg acagtctggt tgtgaggtta
     6181 gaaaacagtt actcctacac cattaaatag ggcgcaatgc tcgctaattt ctcccgggtt
     6241 tctgtcagtt cgcgttccgg cgtagattgc gcgatgattc ccgcccccgc ctgtatccag
     6301 cagcgctggc tatcctgaaa tacggaacgc agaactagcg ctgcatcaaa gcgcgtatcg
     6361 tccagcagca ggattgcgcc ggaataaagc tctcgcggcg tcttctcaat ttgcataatc
     6421 gcgttcagag cagcattttt agggatacct gaggcggtaa tcgacggaaa cagcacggta
     6481 aacgcatccc aggcatcctt gttttccgca agctgaccgc tcacgccaga ccccagatgc
     6541 tgaacgctgc cgcgctggcg aaccgacatt aaatcttcaa ccaccacgct gcccggctgg
     6601 caaacggcct ccagttcagc aatagcttct ttgacagaaa ggatatgctc aagcacctct
     6661 ttactgtcgt gcagcagttc tgcctctttc gccttattat gctccgggtt tcccatgcga
     6721 tcgcgggtgc ccgcaagcgg ttcagtgacc actttattgc ccgtcactga catcaccagt
     6781 tccgggctaa agcccagcgc ttcgcgtcct tcctgacgga acataaacga gcgcacaggt
     6841 gtgtttgcct gccgcccgta taacagcgtg gcgggcatat caatccgcga tggcagggga
     6901 atggcgcgcg agacaatcac tttgacatac tcgccacggc ggatctccgc aacggcgcgc
     6961 gcaacctgtt gtttatatgc ctcaccattg agggcggtat ccaccgccag tggtgcgttc
     7021 tgcgtcgttg taccggcctc ttttacccac tcgcacaaac gtcggcaccc gtcggcggag
     7081 tccgcataaa cggtgacatt tcccttttca aaaataagtt cttcacgggg aacggttaac
     7141 gtcagcagcg gccactcccc ggcgttaaag gcaatccccc gcgcatgcgc cgcaaagttg
     7201 aacccaacct gtccatatac ccgacgtcct ttcacctgag gatgcgccat aaaacgacgc
     7261 gcgcagtcgg caatggaatc caccgcccat ttttgctccc cggcatcatc aataaatgtc
     7321 gcctgcgttc cgtcggcatt aatgtgcagc cgtgcctggc accctttgcc taaataccaa
     7381 cagggttgac gctcatagac ataacactct tcttctgcga actggcgtaa aacgccagaa
     7441 atcgtcggta gccattgttc ctctggtaac gccagatgta gaaattcact gattttcatc
     7501 ccttacctct ctgtgttatt cccggatcaa tcaattgcgc ttgtcatcag ttctcttgcc
     7561 gaatgcagcc ggatataagc aacccacgcc gccagcaacg tgaatgcccc ggcaaacagg
     7621 aagcaggccg catagccaaa atgttgagca acaacgccac cgataacgcc tgccagaatg
     7681 gcgattgccg cgtcagtaca ttgaaagagg gtgaagtcga caccggcctg caaaggcgat
     7741 gaaagcgaca tcagcgtggc gtaaagacag accagcgcgc aggccagcga aatggactgg
     7801 acaatgacca gacactggag aatcggcagc agcagatgac ccggcgccat catgagcgtc
     7861 atcaccaccg ccagcagcgc gatcccctgg acgccataag ccgtcaacag cgctctgccg
     7921 ggtgaggtgt atttcatcag caatccgccg gccagcgttc ctgctatgcc cgctgcaata
     7981 ttgccgccgc tgaacagcgc gcccaatgcg gacatgctca acccatgatc caacaacagc
     8041 ggtgccagaa gaggcagcac aaaccgcatg cctgaattca gcatcaatac cagcagtaag
     8101 cccaggcgcg cctgcttcct ccttagcgca taacctaacg ccggaacatg cgggatagtc
     8161 gctgttcgcg tcggctccgt aatgcgccac agcgggagtg acagcgccat aatcagcacc
     8221 gccatcatca gcatggcgac aggccagccg gatgccgccg acagcatcag gaacaccccg
     8281 ccgccgcaca tcattcccag atagctgccg ccgacctgca cgctgtttcc ccagccgtaa
     8341 cccgtgcggg tcagttgatc gacgcaaaag ccgtcgctgg cgatatcaat ggtggaggcg
     8401 accgtgcctg ccaccataaa cagaacaaat aacgcgacga tttgcgtatc ggggaatccc
     8461 ccttctcgcc caaaccagcc aatcgctgcg gcaatagtca ggatcgccgc tagcgcgacc
     8521 tgaccacgca ggattaacat gcgggaacgg cgttcctggc taccgggcgg aagccgccag
     8581 cgctcgatcc atggcgccca aataaacttc agcgcccagg gcagcataaa cagggttgtc
     8641 gcaccggcaa gcgccagcga accgccagca gcgcgcacca gcgcgggtaa ggactgcata
     8701 gacagcgccg ataccagact ctgcgtcaca tagacgccgg caatagcaaa aatcacccgc
     8761 ccggtcgtca acgtcagcgg tttcacattc gactgaacat cactcatgca cccactctcc
     8821 agacgcggaa accccgtcgt cgcgccacac gcgcgcggcc atttgcgcct gccacagcgc
     8881 ctgataacgt ccatgatgtg agagcaattg cgcatgagta ccctgctcaa ccacctgtcc
     8941 ctcttccatc accagaatgt ttccggcccc ggcgatggtg gataaacggt gagcgatgat
     9001 aatcaccgtc cggttgtgaa ccaggttatc gatcgctttt tgcaccgcca gctcgctttc
     9061 aatatccagc gcggcagtcg gttcatcgag aatgacgacc ggcgcgtttt tcaataacgc
     9121 tctggcaatg gaaatccgct ggcgctcgcc gcccgatagc tggccgccca tctctcccat
     9181 tggcgtcagc cagccttgcg gaagacggga aataaactca aggcactgcg ccgcgcgggc
     9241 ggcctcttct acctcctgcc gcgtcgcctg tgggcgcgcg atacggatat tcgccagcag
     9301 cgtgtcatca aacagccaga catcctggaa aacaacagaa atcaggctat tgagctgttc
     9361 cggcgtcagg cggcgaatat cgacgccgcc aatagaaatc tgcccttgct gcggatcggc
     9421 atagcgcatt aacagtttgg tgaccgtagt tttgcctgcg ccggaggcac ccaccagcgc
     9481 gctcatactg gctgccggga acgtcaaaga aacatgatta agcgcgtggc cgtcgccttc
     9541 ttcgtagcga tagctgacgt tgtcaaagcg gatatcgtaa cgttccggca tctcgctttg
     9601 ctctgcgacg ggaagcggtg ctatcgccat aaaccgctca atccgttgca gggcgctggc
     9661 gatcagttcc acaaccgagg tgtagctgat aaacatcgcc atcggttctg cgaagcgcat
     9721 aatcatcgcg acggcggcaa tcaaaaaggc gaggttcaga gtgcccgtca ctacccagac
     9781 gatcccggat aacaccacca cctgtaggcc caactccacg acgctggcga tcagcatcgt
     9841 cgcgccagcg ccctgacggt gagtgcgggt ctgtaagttt tccagcgcat tgaaatgcgc
     9901 cagcagcgcc cggcttttat cggcatcgct gccgcaggtg cgcaatacca tcatcccctg
     9961 agcaaattca acgatatcgc cgctcagacg ctggtgcgct tcccccagcg tctgcatttg
    10021 tcgccgcatc gccgggcggc gccagtaata aaacggcacc agcagaggga agatcagcaa
    10081 catcaccagc cccagccgcc agtctatcca caatgtcgcc agcgacgccg tcagcggcgt
    10141 gacaatggtg agcagcaaaa tattggctat cgcaataaca taattgaggt tttcatccac
    10201 gttgcccagc agcaaggcgt tcatttcacc cgccctgccg cgctggagct tctccagcgg
    10261 cacgcggcgt aactgctcgc caagtcgcag gcgcaactca tgggtggcct gcgccagatg
    10321 accacggtat tcaaagccca ggccatacca gcgtagcacc agcgtcacaa ttgcggcgac
    10381 gctgaaggcc atagcccagt taagaagttg cggcgcgtct ccccgtaaca gcgcatcaat
    10441 gatcggataa agacaggcaa aggcgatccc ctgcatgaat gccgccagca acagcgccag
    10501 catactgcgt cgcagcatcc tggcctgact gccaacgctg gagataagct ggcgccagat
    10561 gacgcgccag gccaggttat ccgcaggatt attgtctttc attttccacc acctcttcct
    10621 gtgttccacc cggcacccaa tgctgcgcct gctgatagtg ttgccagagc cgttgataca
    10681 ggccgccctg cgccaacagt tgcgtatggt tccccatttc cctgagctgt ccgtcggaaa
    10741 acagcaatat cacatcggcc tgagtcacca ttgagagacg atgcgcgacc atgatgaccg
    10801 tccggccacg catggccgcc gcgagcgcct tgataagcgc cgcttcgttt tccgggtcag
    10861 caaacgccgt cgcctcatcg agcaccagga tggggcgatc ctgcaaaagc gcccgggcga
    10921 tagtaatgcg ctgccgctgg ccgccggaga gaaatacccc acgttccccg actcgtgtgt
    10981 tgtaaccttc tggcagagcg ctaataaaat catgggcctg cgccactctg gccgccgcta
    11041 ttaccgcctc cagcggcgta tccggcgcgc ccagacgaat gttattggct atcgtgtcgg
    11101 caaaaaggaa gttgtcctga aacacaaacg agagttgctt catcagggtg tccgtctgca
    11161 tatcacgcag atccacgccg ccaatacgga tatggccttt gtccgggtcg gcgtaacgca
    11221 gcagcaagcg cgccacggtg ctttttccgg cgccgcttgg cccgaccagc gccacaattt
    11281 gcccggcagg cacatgaaag ctcacctcct gcaacgcggc gccagtacgc gcttgcggat
    11341 aatgaaagct cacctgctca aaggtaatgc tcgcctcttg cggctgctgg tcagactgcg
    11401 gcagcgataa ctccggcatc gcgagaacct gataaatacg ctgaatgctt aaacgcgttt
    11461 gcgcgaccag gttattgagc atcatcattg gcattacggc ttcggccatt ccgctgccca
    11521 gcagtaaaac ggccacccac gcgataaaat cgaaactgcc atagtgcaac aggccgtatc
    11581 ccgaccagat caggacaaac agggtcggga gaggattcag aatcgagaag gaaaaacgcg
    11641 ctgaaaaacc ggctttgcga taccaggttt tgagcacatc gacccactct tcaagggcgc
    11701 gttgatagcg cagaaaactg gtgctgccgc tatcaaacgt tctcaccacg ggcatggcct
    11761 gcacgaactc aataaccgcc gcgctaacct gctcgcgcgc cttatgataa cgctgagcca
    11821 tatcttccga acgctggcgg gcgagcacga gaacaaccga tccaaacgcc agtaccccca
    11881 gcgtcgcgat tgccagccgc cagtccagcc agaacaagat aacgattgtc gccagcggca
    11941 tgatgatcgc gcgggcatag agcggcgtgc tgtcggccac aaaaatatgt aacgacttca
    12001 cgtcatccag catcactttc gccactgacc cgctgcccat ttgctgtaac acgccaggcg
    12061 gaagctgcaa tgctttacgg gctaacctgc tgcgcagaat gttctccaga tgaaaagccg
    12121 cgtaatgaga ggtgttgaac gcctgtaagc gcagaacaaa agttaagacc acgcagccga
    12181 tcacgccgcc cagcggccag gccggaatag cgtcaggcgt cgcgcgaatg tcacgcaggc
    12241 tccacgccag aaaaaggagc gcccccaggc tggttaatgc cgccagcccc gccagcgcca
    12301 tagctaaaat aaccttcctg cgaaccggtg taatcacctg ccagagagga aatcgggaca
    12361 gcgattcagt attggatgat tgagatgaca tgggagcaac tgaatttcct gatgaatttt
    12421 tacggacgcc aaaaacgaca attcagggtg gcgttctgag aattaatgtg aataataacc
    12481 attatcaata actcatctac cccattcggt tctatttata cccgcattgg tctaagccac
    12541 agggagataa ccaggtcatg acggagtcac cgcaaacgca atctgaaatc tctattcacc
    12601 agttggtggt cgggaaacct gcaaacgatg gcaatattcc tgctcagtgt gaactgctgc
    12661 gctgttcgtt gcaggaaggt atggatattt tgctctggag gggccatttt gcgcggcctg
    12721 agacgttgca gctacacgac gatctgggca ggattaactt ctcgtgcatc ctggaaggca
    12781 catcgcgctt tgcgattcag ggactccggc gccacaccga ctgggagctt gcgcgcaatc
    12841 gccattacat tacccatacg ccagactgtc gcggcagcgc ctcctattgt ggccgattcg
    12901 agagcattac cctctccttc agccctgaaa ccctcgcgct gtgggtgccg gatattagcg
    12961 cggtcattaa gaataagatc gactcccact gctgttgcca gcagcagcgt tgtaatgctg
    13021 aaacccactt aacggctcag gccttgcgtc acgcgctgat gcgcatgcac ggcggcttca
    13081 gtcatgaaca aaagccgtcg acgctatggt tgcaggggca aagtctggtc atgctcagtc
    13141 tggtgctgga tgaacatcgc gaagacgcca gttgcctctc ctgccacttc aacccgatgg
    13201 aacgccagaa actgctgcgg gcgaaggatc tgctgctggc tgatctgacg caagcgccgg
    13261 gcgtcgcgga gctggccaga gagtccggtc tgagcgttct caaaattaag cgaggcttcc
    13321 gcgttctgtt caacaacagc gtctatggcc tgtttcaggc tgaacgaatg caggaagcca
    13381 gaagacgcct ggccaacggc aatacctccg tcatgacggt ggcggccgat ctgggctatg
    13441 ccaacgccag ccatttctct gccgccttcc agaaacagtt tggcgtaacc ccttcgacct
    13501 ttaaacgcgt gatgtaaccg gggtcgcgcc cccctaaact cctccctgac agaggcccgg
    13561 ataccccatc cgggcctctg ttctttccgc ctgttaccaa cccgaaacgg gcataaataa
    13621 acccgtttcg ggcagcatcc aattgttaat aattattatt ctcatatgag caatgctttt
    13681 cggtaagacg tgccatcagg aggaagaatg atttctggcg caccatctca ggattcgctg
    13741 ttaccggaca accgccacgc ggctgattac caacaattac gcgagcggct catacaggaa
    13801 ctgaatttaa cgccgcagca gttacatgaa gagagcaacc tgatccaggc cggcctggat
    13861 tccataagat tgatgagatg gttacactgg tttcgtaaaa atggctaccg ccttaccctt
    13921 cgcgagctgt atgccgcccc cacgctggcg gcatggaacc agttaatgct cagccggtcg
    13981 cctgagaacg cggaagaaga aacgccgccc gacgaatcat cctggccgaa catgaccgaa
    14041 agtaccccct tcccattgac gccagtacag cacgcctacc tgacgggccg catgccgggg
    14101 cagacgcttg gcggcgtggg ttgccacctg tatcaggagt ttgaaggcca ttgtctgacg
    14161 gcgtcgcagt tggagcaggc catcacgacc ttgctgcaac gccacccaat gctgcatatc
    14221 gcctttcgcc ccgacgggca gcaggtctgg ctaccgcaac cttactggaa cggcgtcacc
    14281 gttcatgatt tacgccataa cgacgctgaa agccgccagg cctatctgga cgcactgcgc
    14341 cagcgcctga gccaccgtct tttacgcgtg gaaatcggcg aaacgtttga ttttcagctg
    14401 acgctcttgc cggacaatcg ccaccgcctc catgtcaata ttgacctgct gattatggat
    14461 gcctccagct ttacgctttt cttcgatgag cttaacgccc tgctggccgg agaatcgctg
    14521 ccggctatcg acacccgcta tgatttccgc tcgtatttgc tgcaccagca gaagatcaat
    14581 caaacactga gagacgacgc gcgcgcttac tggctggcga aagcatcgac gcttcccccc
    14641 gcgcccgtct tgccgctggc ctgcgaaccc gccacgctac gtgaagtccg taatacccga
    14701 cgccgcatga ttgtcccggc aacacgctgg cacgccttta gcaaccgggc cggcgagtat
    14761 ggcgtgacgc cgacaatggc gctggcgacc tgtttttctg ccgtgctggc tcgctggggc
    14821 ggcctgacgc gtctgctgct taacatcacc ttattcgacc gccagccgct gcacccggcg
    14881 gttggcgcga tgcttgccga cttcaccaat attcttctgc tggataccgc ctgcgatggc
    14941 gataccgtca gcaacctggc gcgtaaaaac cagctcacgt ttacggagga ctgggagcat
    15001 cgccactggt ccggcgtcga attactccgt gaactcaaac gccagcagcg ctacccccac
    15061 ggcgccccgg tggtatttac cagcaatctg gggcgttccc tctacagcag ccgcgcagaa
    15121 tcgccgttgg gcgagccgga atggggcatc tcgcaaacgc cgcaggtctg gatagatcat
    15181 ctggcgttcg agcatcacgg cgaggtctgg ctacaatggg acagcaacga cgcgctgttc
    15241 cctccggcgt tagtcgaaac attgttcgac gcctactgcc agttgattaa ccaactctgc
    15301 gatgacgaaa gcgcctggca aaagccgttc gcagatatga tgcccgccag ccagcgcgcg
    15361 atacgcgaac gggtcaacgc caccggcgcc cccattcccg aaggcttgct gcatgaaggc
    15421 attttccgta tcgctctgca acagccgcag gcgctggcgg taacggacat gcgttatcag
    15481 tggaattatc atgagctgac agactatgcc cgccgttgcg cgggcaggtt aatcgagtgc
    15541 ggggttcagc ccggcgataa tgtggctatc acgatgtcga aaggcgcagg acaacttgtt
    15601 gcggttctgg ccgtcctgct ggccggggcg gtttacgttc cggtttcgct ggatcagcct
    15661 gccgcacggc gcgagaaaat ctacgctgac gccagcgtcc ggctggtgct catttgtcag
    15721 cacgacacca gcgccgggtc agacgatatt cccgtccttg cctggcagca ggccattgag
    15781 gcggagccga tcgccaaccc ggtagtacgc gcccccacgc aaccggccta cattatctac
    15841 acctccggct ctaccggtac gccgaaaggg gtagtcattt ctcaccgggg agcgcttaac
    15901 acctgttgcg atatcaatac ccgctatcag gttggcccgc atgacagggt gctggccctc
    15961 tccgccctac attttgattt atcggtttac gacatttttg gcgtactgcg cgcgggcggc
    16021 gcgctggtga tggtgatgga aaatcaacgg cgcgatcctc acgcatggtg tgagctgatc
    16081 cagcgccatc aggtcacgct ctggaacagc gtcccggcgc tgttcgatat gctgctgacc
    16141 tggtgtgaag gtttcgccga cgccacgccg gaaaacctgc gcgcagtgat gctttccggc
    16201 gactggatcg ggcttgacct ccccgcccgt tatcgggcct tccggccaca aggacaattt
    16261 atcgcgatgg gcggcgccac cgaggcgtct atctggtcta acgcctgcga aattcacgac
    16321 gtccccgccc actggcgctc catcccttac ggttttccgc taaccaacca acgctaccgg
    16381 gtggtggatg aacagggccg ggactgccct gactgggtgc cgggtgaatt atggattggc
    16441 ggcattgggg tcgcggaagg ctatttcaac gatcccctgc gtagcgagca gcaatttttg
    16501 acgctcccgg acgagcgctg gtatcgcacc ggcgatctcg gctgctactg gccagatggc
    16561 acaatcgagt tcctcggtcg tcgcgacaag caggtcaaag tcggaggata tcgcatcgag
    16621 ctgggcgaaa tcgaaagcgc gctcagccag ctggcggggg tgaaacaagc aaccgttctg
    16681 gcgatcggcg aaaaagaaaa aacgctggcg gcatacgttg ttcctcaggg cgaggctttt
    16741 tgcgttaccg atcatcggaa cccggcactg ccgcaggcgt ggcacacgct tgcgggaacg
    16801 ttgccctgtt gcgccatctc gccagagatc tccgcagaac aggtagccga tttccttcag
    16861 catcgcctgc taaaactgaa gccgggtcac accgctggcg ccgatcctct ccccctgatg
    16921 aactcactcg ctatccagcc gcgctggcag gccgtggtgg aactctggtt agcatttctg
    16981 gtgacacaac ggcgactgaa gcccgctgct gaaggttatc aggtctgcgc tggtgaagaa
    17041 cacgaggatg agcacccgca cttcagcgga catgatttaa cgttatcaca aattcttcgc
    17101 ggtgcccgta acgaactgtc gttactgaac gacgcgcagt ggtcgccgga aagcctggcc
    17161 tttaaccatc cggccagcgc cccgtatatt caggaactgg cgacaatttg ccaacagctt
    17221 gcacagcgct tacagcgccc ggtacgcctg cttgatgtgg gaacccgcac tggccgcgcc
    17281 gcagaatcgc tgttagcaca gctcaacgcc ggacagattg agtatgtcgg gcttgagcag
    17341 agccaggaga tgctgctgag cgcccggcag aggctcgccc cctggcctgg cgcccgtctg
    17401 tccctctgga atgcagacac gctggcggcg cacgctcact cggcggacat tatctggctt
    17461 aataacgccc tgcatcgtct gctgccggaa gatcccgggc tccttgcgac attacaacag
    17521 cttgccgttc ccggcgcgct gctctacgtg atggagtttc gccagttaac gccgtccgcc
    17581 ctgctcagca cgctcctgtt aaccaatggg cagccggagg ccttgctgca taacagcgcc
    17641 gactgggcgg cattatttag cgcggccgcc ttcaactgtc agcatggcga tgaggtcgcg
    17701 gggttacaac gcttcctcgt acaatgtcct gacaggcagg tgcgccgcga tccccgtcaa
    17761 cttcaggccg ccctcgccgg acgtctgccg gggtggatgg tgccgcaacg gatcgtcttc
    17821 ctcgacgcct taccgctgac ggctaacggg aaaattgact accaggcgct gaagcgtcgt
    17881 catacccctg aagcggaaaa cccggccgaa gcggatttac cccagggcga cattgaaaaa
    17941 caggttgccg ccctctggca gcaactctta tcaactggca atgtcaccag agaaaccgac
    18001 ttcttccagc aaggcggcga tagcctgctg gcgacccgtc tgaccgggca acttcatcag
    18061 gcaggttatg aagcgcaatt aagcgacctg tttaatcatc cccggctggc ggattttgcc
    18121 gccacgctgc ggaaaaccga cgtcccggtc gaacaaccat tcgtccactc ccctgaagaa
    18181 cgctaccagc cctttgcgct taccgacgtg cagcaggctt acctggtggg gcgtcagccg
    18241 ggctttgccc tgggcggcgt cggctcacat ttctttgttg aatttgaaat tgccgatctg
    18301 gacctcaccc ggctggagac ggtctggaac cgattaatcg cccgccacga tatgctgcgc
    18361 gccatcgtgc gtgatggaca gcaacaggtg ctcgaacaga cgcccccctg ggtgataccc
    18421 acacacaccc tccatacgcc tgaagaggcg ttgcgggtgc gcgaaaaact ggcgcatcag
    18481 gtactcaacc ccgaagtgtg gccggtattc gatctccagg tcggatacgt ggacgggatg
    18541 cctgcccgcc tgtggctgtg tctggataac ctgttgcttg acggtctgag catgcagatc
    18601 ctgctggcgg agctggagca cggctaccgc tacccgcaac agctgcttcc gccgctgccc
    18661 gtcaccttca gggattatct gcaacaaccc tcgctacagt cgcccaatcc agattctctg
    18721 gcatggtggc aggcgcagct tgatgatatt cctccggcgc ctgcgttgcc gctgcgctgc
    18781 ttgcctcagg aggttgaaac accgcgcttc gcccgcctga acggcgcgct ggacagcacg
    18841 cgctggcatc ggctgaaaaa acgggcggct gacgcccatc tcaccccgtc ggccgtactg
    18901 ttgtcggtgt ggtcaacggt tctctctgca tggagtgcac agcctgagtt cacgcttaac
    18961 cttacgcttt tcgacaggcg accgctgcac ccgcaaatca accagattct gggcgatttc
    19021 acctcgctga tgctgctgag ctggcatccc ggcgaaagct ggctgcacag cgcgcagtca
    19081 ctacagcagc ggctgagcca gaacctcaac caccgcgatg tgtcagccat ccgcgtgatg
    19141 cgtcaactgg cgcaacggca aaacgtgcct gccgttccga tgcccgtcgt ctttaccagc
    19201 gcgctgggct ttgagcagga taacttcctc gcccggcgta atctgctcaa accggtctgg
    19261 ggcatctccc agacgccgca ggtctggctc gatcaccaga tttatgaatc cgaaggcgaa
    19321 ctgcgcttta actgggattt tgtcgccgcg ctgtttcctg ccgggcaggt ggagcgccag
    19381 tttgaacagc attgcgcatt gctaaaccga atggccgagg atgaaagcgg ctggcaactg
    19441 ccgctcgccg cgctggtgcc tcccgttaaa cacgcagggc aatgcgcaga gcgctcaccg
    19501 cgcgtatgcc ctgagcactc tcagccacac attgcggcgg acgagagcac cgtcagcctg
    19561 atttgcgacg ccttccgcga ggtggttggc gagtctgtca cgcccgcaga aaacttcttt
    19621 gaggcgggcg caacgtcgct gaatctggtg caactgcacg ttttgttaca acgtcacgaa
    19681 ttttccaccc tgacgttgct tgacctcttc acccaccctt ctcctgctgc cctggccgat
    19741 tatctggccg gcgtcgccac ggtggagaaa acaaaacgac ctcgccctgt tcgccgtcgt
    19801 cagcggcgga tatagcgcga agcaaactga ttttccccgg aacgccatcg cgaacgcatg
    19861 gcgttccatt gactttgtga atcttaggaa acgggaccga ttatggataa cttgcgcttc
    19921 tcttctgcgc cgacagcaga ttccattgat gcatcgatcg ctcaacacta cccggactgc
    19981 gaacctgtcg cggttatcgg ctacgcctgc cattttcctg aatcgccgga tggcgaaacg
    20041 ttctggcaaa atctgctgga aggtcgtgaa tgcagccgac gctttacgcg cgaagagctt
    20101 ctggccgtcg gtctggatgc cgccatcatt gacgatcctc attatgtcaa tatcggtacg
    20161 gtgttagaca acgccgactg cttcgacgcc accctgtttg gctattcgcg acaggaagcg
    20221 gagtcgatgg acccgcagca gcgcctattt ttgcaggcgg tctggcatgc gctggaacat
    20281 gccggttatg cccccggcgc cgtcccccat aagaccggcg ttttcgcctc ttcccggatg
    20341 agtacctacc ccggtcgcga agcattgaac gtgacagaag tcgcgcaggt aaaaggtctg
    20401 caatctctga tgggcaatga taaagactat attgccaccc gcgccgcgta caaactcaac
    20461 ctgcacggcc cggcgttatc ggtacagacc gcctgctcca gctcgctggt tgcagtgcat
    20521 ctggcctgtg aaagcctgcg cgcaggcgaa tccgatatgg cggttgccgg cggcgtggcg
    20581 ctctctttcc cccagcaggc aggctaccgc taccagcccg gaatgatttt ctctcctgat
    20641 ggtcactgtc gtccctttga cgcctcggct gagggcacct gggccggtaa cggtctcggc
    20701 tgcgtggtgc tgcgtcgcct gagagacgcg ctgctgtcag gcgatccgat tatctcggtg
    20761 atcctctcca gcgcggtcaa caacgacggc aacagaaagg tcggctatac cgccccttcc
    20821 gtcgcagggc aacaggcagt catcgaagag gcgttaatgc tggcggccat cgacgacagg
    20881 caggtaggtt acattgaaac ccacggcacc ggcacaccgc tgggcgacgc gattgaaatt
    20941 gaagcgttac gcaacgtcta tgcgcctcgc ccgcaggatc agcgctgtgc gctcggttcc
    21001 gtgaaaagta acatgggcca tctggatacc gcggcgggca ttgccggact gctgaaaacc
    21061 gttctggcag tcagtcgcgg gcaaattcct cccttactga attttcacac ccccaacccg
    21121 gcgctgaaac ttgaagagag cccctttacc ataccggtgt cggcacaggc atggcaggac
    21181 gaaatgcgct atgcgggcgt ctcctccttt ggtattggcg gcaccaactg ccatatgatc
    21241 gtcgcctcgc tgcccgacgc gctcaacgcg cgcctccccg atacggatag cggcagaaaa
    21301 agtaccgcgc tgctgctcag cgccgccagc gacagcgcgt tgcggcggct ggcgacggat
    21361 tatgccgggg cgctgagaga ggatgcggat gccagctctc tggccttcac agccctgcac
    21421 gcgcgccgtc tcgatctccc cttccgcctg gcggcgccat taaaccgtga aaccgccgag
    21481 gcgctcagcg cctgggccgg tgagaaatcg ggggcgctgg tttacagcgg ccacggcgcc
    21541 agcggcaagc aggtgtggct gtttaccggc cagggctcgc actggcgcac tatgggtcaa
    21601 acgatgtacc agcactcaac ggcgtttgcc gacacgctgg atcgctgttt ttccgcctgt
    21661 agcgaaatgc tcacgccgtc actgcgcgaa gcgatgttta accccgattc ggcgcagctg
    21721 gacaatatgg cctgggcgca gccggcgatt gtcgcgtttg aaatcgcgat ggcggcgcac
    21781 tggcgtgctg aaggactgaa gccagacttc gccattgggc attccgtcgg tgaatttgcc
    21841 gctgccgttg tctgcggaca ctatacgatt gaacaggtca tgccactggt ttgtcggcgc
    21901 ggcgcgctaa tgcagcagtg cgcaagcggc gcgatggtgg cggtatttgc agacgaagac
    21961 acgctgatgc cgctggctcg ccagtttgag ctggatctcg ccgccaacaa cggtacgcaa
    22021 catacggtat tttccgggcc ggaagcccgt ctcgcggtat tttgcgccac gctctcgcag
    22081 catgacatta actatcgtcg cctgagcgta accggtgcgg cgcactccgc tttactggag
    22141 ccgatactcg atcggttcca ggacgcctgc gcgggactgc acgcggagcc ggggcaaata
    22201 ccgattattt ccacgctcac cgccgacgtc attgatgagt caacgctcaa ccaggcggat
    22261 tactggcgcc gacacatgcg ccagccggtg cgttttatcc agagtattca ggtggcgcat
    22321 cagctcggcg cccgcgtttt tctggagatg gggcccgatg cccagttggt tgcttgcggg
    22381 cagcgcgaat accgcgataa cgcatactgg atagccagcg cccggcgtaa caaagaggcg
    22441 agcgatgtcc tcaatcaggc cctgctccag ctttacgctg ccggcgtcgc cctaccgtgg
    22501 gccgacctgc tggcgggcga tggacaacgt atcgctgcgc catgttatcc gtttgatact
    22561 gagcgttact ggaaagagcg cgtctccccg gcctgcgagc ctgccgacgc agcgctgtct
    22621 gccgggctgg aggtggcgag tcgcgccgcg acagcgctcg atctccctcg cctggaagcg
    22681 cttaaacagt gcgccacgcg actgcacgcc atctacgtcg atcaactggt acaacgctgt
    22741 accggcgatg ccattgagaa cggcgtggac gccatgacca tcatgcgccg tggacgtctg
    22801 ctgccccgct accagcagct actccagcgc ctgctgaata actgcgtggt cgacggcgat
    22861 taccgctgca ccgacgggcg atacgtccgc gcccgcccca ttgaacatca acagcgggaa
    22921 tcactgctga cggaacttgc cggttattgt gaaggttttc aggctattcc cgacaccatc
    22981 gcccgtgccg gcgatcggtt atatgaaatg atgagcggcg cggaagaacc ggtggcgatt
    23041 atcttcccgc aaagcgcctc cgacggcgtg gaagtgctgt atcaggaatt cagctttggc
    23101 cgctatttca accaaatcgc cgccggggta ttacgcggca ttgtccagac gcgtcagccc
    23161 cgccagccgt tgcgtattct tgaagttggc ggcggaaccg gcggcaccac cgcgtggctg
    23221 ctgccggaac tcaacggcgt tccggcactg gagtaccatt tcaccgatat ctcggcgctg
    23281 ttcacccgtc gcgcccagca gaaattcgcc gactatgatt ttgtgaagta tagcgagctg
    23341 gatctcgaaa aagaggcgca gtctcagggt ttccaggcac agtcttacga tcttatcgtg
    23401 gcagcgaacg tgattcacgc cacccgccat attggccgca cgctcgataa tctgcgcccc
    23461 ctgctcaagc cgggcgggcg cctgctgatg cgcgaaatca cccagccaat gcgtctgttt
    23521 gacttcgttt tcggcccgct ggttcttccg ctacaggatc tcgacgcccg cgaaggtgag
    23581 ttattcctca ccaccgctca gtggcaacaa cagtgccgcc acgccggatt cagcaaagtg
    23641 gcgtggctac cgcaggatgg cagcccgacc gccgggatga gcgaacatat cattctcgcc
    23701 acgctgcccg gtcaggcggt tagcgccgta acattcaccg cgccatcaga acccgtgttg
    23761 gggcaggcgc tgacggataa cggtgattat ctcgccgact ggtctgattg cgcaggtcag
    23821 cccgaacggt ttaacgcccg ctggcaggag gcctggcgtc tgctttcaca gcgtcatggc
    23881 gacgctctac ctgtggaacc gccccccgtc gccgccccgg agtggctggg gaaggttcgc
    23941 ttaagctggc aaaacgaagc cttttcccgc ggtcagatgc gcgttgaagc ccgtcatcct
    24001 gctggcgagt ggctgccgct atcgcccgcc gcgcctcttc ctgcgccgca gacgcattat
    24061 caatggcgct ggacgcccct caacgtcgcc agcattgacc atccgcttac ctttagcttc
    24121 agcgccggta cgcttgcgcg cagcgacgag ctggcgcaat acggcatcat tcacgatccg
    24181 cacgcctctt cgcgactgat gattgttgag gagagcgagg atacgctggc cttagcggag
    24241 aaagtgatag cagcgctcac cgccagcgca gccggattga ttgtggttac tcgccgcgcg
    24301 tggcgagtcg aggaaaatga agcactctct gcatcccatc acgcgctatg ggccttgctt
    24361 cgcgtcgcgg ccaacgaaca gccggaacgg ttgcttgccg ccatcgatct cgccgaaaac
    24421 accccgtggg aaacgctgca tcaagggttg agcgcagtct cactatcaca gcgctggctc
    24481 gccgcacggg gtgacaccct ttggctccct tcactggcgc ccaatacggg atgcgccgct
    24541 gaattaccgg caaacgtgtt taccggcgat agccgctggc atctggtgac cggagcgttt
    24601 ggcggattag gccgccttgc cgtgaactgg ctcagagaaa aaggggcgcg acgcatcgcc
    24661 ctgctggcgc cgcgcgtgga tgagtcatgg ctacgcgacg tggagggcgg gcagacgcgc
    24721 gtctgccgtt gtgatgtggg cgatgccggg caactggcca cggttcttga cgatctggcg
    24781 gccaacggcg gcattgccgg agcgattcat gccgctggcg tattggctga cgcgcccttg
    24841 caggagcttg atgaccacca gttggctgcc gttttcgcgg taaaagcgca ggcggcaagc
    24901 cagctgttgc aaaccctgcg caaccacgac ggacgctatc ttattctcta ctcttccgct
    24961 gccgccaccc tcggcgcgcc gggtcagagc gcccatgcgc tggcctgcgg ctacctggac
    25021 gggctggccc agcagttttc cacccttgat gcgccgaaaa cgctctctgt cgcctggggc
    25081 gcatggggag aaagcggtcg ggcggccacg ccggaaatgc tggcgacgct cgccagccga
    25141 ggtatgggcg cgttaagcga tgccgaaggc tgctggcacc tggaacaggc ggtgatgcgc
    25201 ggcgccccgt ggcgactggc gatgcgcgtt tttaccgaca aaatgccccc gttacaacag
    25261 gctctgttta acatcagcgc cacagaaaaa gccgcaacgc cggtcattcc tcctgctgat
    25321 gacaacgcct ttaacggcag cctgagcgat gaaacagcgg tgatggcatg gctgaaaaag
    25381 cggattgcgg ttcagctaag gctgagcgat ccggcgtcac tgcatccaaa ccaggatctg
    25441 ttgcaactcg gcatggactc gctgctcttc cttgaactca gtagcgatat tcagcactac
    25501 ctgggcgtac gcatcaatgc ggaacgggcg tggcaggatc tgtctcctca tggactcacg
    25561 cagcttatct gttctaagcc agaggcgacg cctgccgctt cgcagccgga agtgttgcgg
    25621 cacgacgccg acgagcgtta tgcgcccttc cctttgacgc ccattcagca cgcctactgg
    25681 ctggggcgaa cccacctcat tggctatggc ggcgtcgcct gtcacgtcct gtttgagtgg
    25741 gataaacgcc acgatgagtt caatctcgcc atactggaga aagcatggaa ccagctcatc
    25801 gcacgccacg atatgttgcg tatggtggtt gatgccgacg ggcagcagcg aatcctggcg
    25861 acaacgccgg agtatcacat cccgcgtgac gatctgcgcg cgctttcccc ggaagaacag
    25921 cgcatcgcgc tggaaaaacg gcggcatgaa ctgagctatc gcgttttgcc tgccgaccag
    25981 tggcctcttt ttgagctggt ggtcagcgaa atcgacgatt gccattaccg tctgcatatg
    26041 aacctcgacc ttttgcagtt tgatgtgcag agttttaaag tcatgatgga cgacctggcg
    26101 caggtctggc gcggtgaaac gctggcgccg ctcgctatta ccttccgtga ttatgtgatg
    26161 gctgaacagg cgcgccgaca gacatcggca tggcacgatg cctgggatta ctggcaggaa
    26221 aaactgccgc aactgccctt agcgccagag ctgccggtgg ttgagacgcc cccggaaacg
    26281 ccacacttca ccaccttcaa atcgacgatc ggcaagacag aatggcaggc cgtgaaacag
    26341 agctggcagc agcaaggcgt cacaccgtct gccgcgctgc tcacgctgtt tgccgccacc
    26401 cttgagcgct ggagccgtac cacaacattt acgctgaacc tgacgttctt caatcgccag
    26461 ccgatccatc cgcaaatcaa ccagttgatt ggtgatttta cctccgtcac gctggttgat
    26521 tttaacttct cagcgccggt gacgttgcaa gagcagatgc aacagaccca acagcgcctc
    26581 tggcaaaaca tggcgcacag tgaaatgaac ggtgttgagg tgatccgtga gctgggccgc
    26641 ctgcgcggat cacaacgtca accgctgatg ccggtagtgt ttaccagtat gctggggatg
    26701 acgctggaag gcatgactat cgatcaggcg atgagccatc tgttcggcga accctgctat
    26761 gtattcacgc aaacgccgca ggtctggctg gatcatcagg tcatggagag cgacggcgag
    26821 ttgatgttta gctggtactg catggacaac gtgctggaac ccggcgctgc cgaggcgatg
    26881 tttaatgact attgcgccat cctgcaagcc gtcatcgccg cccctgaaag cctgaagact
    26941 ctcgccagcg gcatcgccgg gcacattccc cgccgacgct ggccgctgaa cgcgcaggcg
    27001 gactacgacc tgcgggatat tgagcaggcg acgctcgaat accccggcat ccggcaggcc
    27061 agagcggaaa taaccgaaca gggcgcgttg acgctggata tcgtgatggc cgacgatccg
    27121 tcgccatcag cggcgatgcc tgatgagcac gaacttaccc aactggcgct gccgttgcct
    27181 gagcaggcgc agcttgatga gctggaggcg acctggcgct ggctggaggc gcgtgcgcta
    27241 caggggatcg cggctacgct aaatcgtcac ggcctgttta ccacgccgga gatcgcccat
    27301 cgctttagcg caatagtaca ggcgctgtcc gcgcaagcgt ctcaccagcg tctgctgcgc
    27361 cagtggctac agtgtctgac ggaaagagag tggttaatcc gcgaaggtga aagctggcgc
    27421 tgccgcattc cgctcagcga gattcctgag cctcaggaag cgtgcccgca aagccaatgg
    27481 agccaggcgc tggcgcagta tctggaaacc tgcatcgccc ggcacgacgc cctcttctcc
    27541 gggcagtgtt ctccgctgga attgctgttc aacgagcagc atcgcgttac cgacgcgctg
    27601 tatcgcgaca accccgccag cgcctgtctg aatcgctata ccgcgcagat tgccgccttg
    27661 tgcagcgcag aacggattct ggaggttggc gctggaaccg cagccactac cgcgccggtg
    27721 ctgaaggcca cgcggaacac gcggcagtcg taccacttca cggacgtctc cgcgcagttc
    27781 ctcaatgacg ccagagcccg tttccatgat gaatcgcagg tgtcttatgc cttgttcgac
    27841 atcaaccagc cgctggattt caccgcccac ccggaggcgg gttacgacct gatcgttgcc
    27901 gtcaatgtgc tccacgacgc cagccatgtc gtccagacgt tgcgcagatt aaaactgttg
    27961 ctgaaagccg gcggacgttt gatgatcgtt gaagcgacgg agcgaaacag cgtattccag
    28021 ctggcgagcg tgggctttat tgagggatta agcggatacc gcgatttccg ccgccgggat
    28081 gagaaaccga tgctcacccg ctccgcatgg caggaggttc tcgttcaggc cgggtttgca
    28141 aacgagctgg cgtggcccgc gcaggaatcg tcgccgctgc gccagcatct gctggtggcg
    28201 cgttcgcctg gcgtaaatcg cccggataaa aaagccgtga gccgctattt acagcagcgc
    28261 tttggcaccg gtctgcccat tttacagatc cggcaaagag aagcgttatt tacgccgctg
    28321 catgccccgt ctgatgcgcc gactgagcca gccaaaccca cgccagttgc cggggggaat
    28381 ccggcgctgg aaaaacaggt ggctgaactc tggcaatcgc tgctgtctcg ccccgtggca
    28441 aggcatcacg actttttcga actgggcggc gacagcctga tggcgacaag gatggtcgcg
    28501 cagctaaacc ggagagggat tgccagggct aaccttcagg atctgttcag ccattcgacg
    28561 ctgagcgact tctgcgccca tctacaggcg gctacgtcag gagaggacaa cccgataccc
    28621 ctttgccagg gcgacggtga ggaaaccctg tttgtcttcc acgcttcaga cggcgatatc
    28681 agcgcctggc tgccgctcgc tagcgcgttg aacaggcgcg ttttcggcct gcaagcaaaa
    28741 tcgccgcagc gctttgccac gctcgaccag atgatcgatg agtatgtcgg gtgcatccgt
    28801 cgtcagcagc ctcacggccc ttatgtgctg gcgggttggt cgtatggcgc gtttcttgcg
    28861 gcgggcgccg cacagcgcct gtacgccaaa ggcgagcagg ttcggatggt gttaatcgat
    28921 cccgtgtgcc gacaggattt ctgttgcgaa aaccgggcgg ccctgctgcg cctgttagcc
    28981 gaaggacaaa cgcctctggc actgcccgaa catttcgacc agcagacgcc cgacagccag
    29041 cttgccgact ttatcagcct cgctaaaacg gccggtatgg tgccgcaaaa cctgacgctg
    29101 caagcggcag aaacgtggct cgacaacatc gcgcatctgc tgcgtttact gactgagcat
    29161 acgccgggcg aaagcgttcc ggtcccctgt ctcatggtgt atgccgccgg gagacccgcg
    29221 cgctggacgc cagcagaaac cgagtggcag ggctggataa acaacgccga cgacgctgtg
    29281 attgaagcca gccactggca aatcatgatg gaagcccccc acgttcaggc ttgtgcgcaa
    29341 cacattacgc gctggctttg cgcaacctca acgcaaccgg agaacacgtt atgatgccgt
    29401 ccgcctcccc aaaacaacgc gtactgattg tgggcgccaa atttggcgaa atgtacctga
    29461 atgcctttat gcagcccccg gaggggctgg aactggtcgg cctgctggcg cagggaagcg
    29521 cccgttcaag agagctggct catgcgtttg gcattccgct gtatacctcg ccggaacaga
    29581 taaccaggat gccggatatc gcctgtattg tcgtgcgttc gaccgtcgcc ggaggaaccg
    29641 gtacgcagct tgccagacac tttctgacgc gcggcgtaca cgtcattcag gagcatcccc
    29701 tccacccgga tgacatcagt tccttacaaa cgctggcgca ggaacagggc tgctgctatt
    29761 gggtaaacac gttttatccg catacgcgcg cgggacgcac atggcttcgc gatgcgcagc
    29821 agctgcgtcg ctgcctggct aagacgccgc cggtagtcca cgccaccacc agccgacagt
    29881 tgctctactc cactctggat ttgttgttgc tggctctggg cgttgatgcc gccgccgtgg
    29941 agtgcgacgt ggttggcagc tttagcgatt ttcactgtct gagactcttc tggccggagg
    30001 gagaagcctg cctgctgctt cagcgctatc tcgatcctga cgatccagat atgcatagcc
    30061 ttatcatgca ccgcctgctg ctgggctggc cggaaggtca tctttcgctg gaggcgagct
    30121 acggccccgt catctggtca tccagcctgt ttgtcgcaga ccatcaggag aacgcccaca
    30181 gcctctaccg cagaccggag atcctgcgcg atctgccggg tctgacgcgc agcgcggcgc
    30241 ccctgagctg gcgcgactgc tgcgaaaccg tcgggccgga gggcgtcagc tggttgctac
    30301 accagttgcg cagccatctg gcgggcgaac atccaccagc ggcctgccaa agcgtacatc
    30361 agatcgcgtt atcacgttta tggcagcaga ttttacgtaa gaccggcaat gcggagatca
    30421 gacgcctgac gccgccgcac cacgaccggt tagccggttt ctacaacgat gatgataagg
    30481 aggcgctgtg acgcaatctg caatgtgcat cccgctgtgg cccgcccgaa acggtaatac
    30541 tgcgcatcta gtcatgtgcc ctttcgctgg cggcagcagt agcgcgtttc gccactggca
    30601 agctgagcaa ctggctgatt gcgcgctttc tctggtgacc tggccggggc gcgatcgcct
    30661 tcgccatctg gaaccgctca gaagcattac acaactggcg gcactgctgg cgaacgagct
    30721 ggaagcatcc gtatcgcctg acacgccgct tttactcgcc gggcacagca tgggggcaca
    30781 ggtggcgttt gaaacctgcc gacttctgga gcaacggggg cttgcgccac aaggactgat
    30841 tatttccggg tgccatgccc cgcatctgca ttctgaacgc cagctcagcc atcgcgatga
    30901 tgccgacttt atcgctgagc tgatagacat tggcggatgt tctcctgaac tgcgggaaaa
    30961 ccaggaatta atgtcgctgt ttcttcctct tctgcgcgct gatttttacg ccaccgagag
    31021 ctatcactac gactcgcccg acgtctgtcc gccgctgcgc acgcctgcgc tgttattgtg
    31081 cggcagccac gatcgcgaag cctcctggca gcaggtcgat gcctggcgtc agtggctgag
    31141 ccccgttaca ggcccggtgg tgattgacgg cgatcatttc tatcccattc aacaagcccg
    31201 gtcctttttt acgcagattg tccgccattt tccccacgca ttttctgcaa tgaccgcgtt
    31261 gcaaaaacag cccagtactt cagaaaggtg acgcatgaat tcttcctttg aatctctgat
    31321 tgaacagtat cccttaccca ttgccgaaca gttgcgccac tgggcggccc gttatgcctc
    31381 gcgaattgcc gtcgttgatg caaaggggtc gttaacctac agcgcgcttg atgcacaagt
    31441 tgacgaactt gccgcaggtc tgtcatcact gggtttgcgt tcgggggagc atgtaattgt
    31501 gcagcttccc aacgacaacg cgtttgttac cctgctgttc gccttgttaa gactgggcgt
    31561 tatccccgtg ctggcgatgc cctcgcaacg ggcgctggat atcgacgcgc tgattgagct
    31621 ggcgcaaccc gtcgcttacg ttattcacgg ggaaaaccac gcagagctgg cccgacagat
    31681 ggcgcacaaa cacgcctgct tgcgtcatgt tctggtcgct ggagagaccg tgagcgacga
    31741 ttttacgccg ctcttctccc ttcacggtga gcgacaggca tggccgcagc ctgatgtttc
    31801 cgccaccgcg ttgttgttgc tctcaggcgg cacaaccggc acgcccaaac tcatcccgcg
    31861 ccgacatgcc gactatagct ataacttcag cgcttctgct gaactgtgcg gcatcagcca
    31921 acagagcgtg tatctcgccg tcctcccggt ggcgcataac tttccgctgg cctgccccgg
    31981 tattctggga acgcttgcct gcggcggaaa agtggtgctg accgacagcg ccagctgtga
    32041 tgaggtgatg cctttaatcg cgcaggaaag agtgactcac gtcgccctgg ttccggcgct
    32101 ggcgcaatta tgggtgcagg ccagggagtg ggaagacagc gacctttcgt cgctgcgcgt
    32161 cattcaggca ggcggcgccc ggctcgaccc gacgcttgct gagcaggtta tcgccacctt
    32221 tgactgtacc ctgcaacagg ttttcggtat ggcggaaggc ctgctctgtt ttacccggct
    32281 ggacgatccg catgccacca ttctccacag ccaggggcgc ccgttgtccc ctctggatga
    32341 aatccgcatc gttgatcaag acgagaacga cgtcgcgccg ggcgaaaccg ggcaattgtt
    32401 aacgcgcggc ccttatacca tttcgggcta ttaccgcgcc cctgcccaca acgcgcaggc
    32461 ctttaccgcg caagggtttt accgcacagg cgacaatgtc aggctggatg aggtggggaa
    32521 cctgcacgtt gagggacgca taaaagagca gatcaaccgc gccggagaaa aaatagccgc
    32581 ggctgaagtg gaatcggcac tgctgcgttt agcggaagtg caagattgcg cggtggtcgc
    32641 cgcgccggac acgctgcttg gcgagcggat ttgcgcgttt atcatcgcgc agcaggtgcc
    32701 aactgactat cagcagttgc gtcaacaact gacccgtatg gggctcagcg cgtggaaaat
    32761 tcctgaccaa atcgagtttc tggaccactg gccgctcacc gccgtcggca agatagacaa
    32821 aaaacgcctg acggctctcg ccgtcgaccg ttatcgccat tctgcccaat aagcgcaaac
    32881 cgacccgaaa caggttgaaa taaacccgtt tcgggtagca ccactattag aaatagttat
    32941 cattttcaat tcaccattgt cggtattttt ggcgtttcgc cgtcttacag ggactcacaa
    33001 caatgaaaat gacacggctt tatcctctgg ccttgggggg attattgctc cccgccattg
    33061 ctaatgccca aacttcacag caagacgaaa gcacgctggt ggttaccgcc agtaaacaat
    33121 cttcccgctc ggcatcagcc aacaacgtct cgtctactgt tgtcagcgcg ccggaattaa
    33181 gcgacgccgg cgtcaccgcc agcgacaaac tccccagagt cttgcccggg ctcaatattg
    33241 aaaatagcgg caacatgctt ttttcgacga tctcgctacg cggcgtctct tcagcgcagg
    33301 acttctataa ccccgccgtc accctgtatg tcgatggcgt ccctcagctt tccaccaaca
    33361 ccatccaggc gcttaccgat gtgcaaagcg tggagttgct gcgaggccca cagggaacgt
    33421 tatatggcaa aagcgctcag ggcgggatca tcaacatcgt cacccagcag ccggacagca
    33481 cgccgcgcgg ctatattgaa ggcggcgtca gtagccgcga cagttatcga agtaagttca
    33541 acctgagcgg ccccattcag gatggcctgc tgtacggcag cgtcaccctg ttacgccagg
    33601 ttgatgacgg cgacatgatt aaccccgcga cgggaagcga tgacttaggc ggcacccgcg
    33661 ccagcatagg gaatgtgaaa ctgcgtctgg cgccggacga tcagccctgg gaaatgggct
    33721 ttgccgcctc acgcgaatgt acccgcgcca cccaggacgc ctatgtggga tggaatgata
    33781 ttaagggccg taagctgtcg atcagcgatg gttcaccaga cccgtacatg cggcgctgca
    33841 ctgacagcca gaccctgagt gggaaataca ccaccgatga ctgggttttc aacctgatca
    33901 gcgcctggca gcagcagcat tattcgcgca ccttcccttc cggttcgtta atcgtcaata
    33961 tacctcagcg ctggaatcag gatgtgcagg agctgcgcgc cgcaaccctg ggcgatgcgc
    34021 gtaccgttga tatggtgttt gggctgtacc ggcagaacac ccgcgagaag ttaaattcag
    34081 cctacgacat gccgacaatg ccttatttaa gcagtaccgg ctataccacc gctgaaacgc
    34141 tggccgcata cagtgacctg acctggcatt taaccgatcg ttttgatatc ggcggcggcg
    34201 tgcgcttctc gcatgataaa tccagtacac aatatcacgg cagcatgctc ggcaacccgt
    34261 ttggcgacca gggtaagagc aatgacgatc aggtgctcgg gcagctatcc gcaggctata
    34321 tgctgaccga tgactggaga gtgtataccc gtgtagccca gggatataaa ccttccgggt
    34381 acaacatcgt gcctactgcg ggtcttgatg ccaaaccgtt cgtcgccgag aaatccatca
    34441 actatgaact tggcacccgc tacgaaaccg ctgacgtcac gctgcaagcc gcgacgtttt
    34501 atacccacac caaagacatg cagctttact ctggcccggt cgggatgcag acattaagca
    34561 atgcgggtaa agccgacgcc accggcgttg agcttgaagc gaagtggcgg tttgcgccag
    34621 gctggtcatg ggatatcaat ggcaacgtga tccgttccga attcaccaat gacagtgagt
    34681 tgtatcacgg taaccgggtg ccgttcgtac cacgttatgg cgcgggaagc agcgtgaacg
    34741 gcgtgattga tacgcgctat ggcgcactga tgccccgact ggcggttaat ctggtcgggc
    34801 cgcattattt cgatggcgac aaccagttgc ggcaaggcac ctatgccacc ctggacagca
    34861 gcctgggctg gcaggcgact gaacggatga acatttccgt ctatgtcgat aacctgttcg
    34921 accgtcgtta ccgtacctat ggctacatga acggcagcag cgccgtcgcg caggtcaata
    34981 tgggtcgcac cgtcggtatc aatacgcgaa ttgatttctt ctgattattg taaaagggat
    35041 accgaaaagg tatccctttt acaccactag ttaaaaccag taactcagca gagtcgcaaa
    35101 aaatattaat ccatagtgat tatttaaaca atgaaattgc gattaggaca aatagattta
    35161 actttctcgt tcctttctct ccttatacta aagaaataat catatcaaaa taaaaattca
    35221 caacagtgca acattaaaaa taca
//
LOCUS       DAPOAV010000046        34527 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.046, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000046 DAPOAV010000000
VERSION     DAPOAV010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 34527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34527
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.046"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(237..1178)
                     /gene="fabY"
                     /locus_tag="RN951_002487"
                     /gene_synonym="yiiD"
     CDS             complement(237..1178)
                     /gene="fabY"
                     /locus_tag="RN951_002487"
                     /gene_synonym="yiiD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001666856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid biosynthesis protein FabY"
                     /protein_id="HDX2527470.1"
                     /translation="MYHLRVPQTEEELERYYQFRWEMLRKPLHQPKGSERDAWDAMAH
                     HQMVVDEQGNLVAVGRLYINADNEASIRFMAVHPDVQDKGLGTLMAMTLESVARQEGV
                     KRVTCSAREDAVEFFAKLGFVNQGEITTPTTTPIRHFLMIKPVATLDDILHRGDWCAQ
                     LQQAWYEHIPLSEKMGVRIQQYTGQKFITTMPETGNQNPHHTLFAGSLFSLATLTGWG
                     LIWLMLRERHLGGTIILADAHIRYSKPISGKPHAVADLGALSGDLDRLARGRKARVQM
                     QVEIFGDETPGAVFEGTYIVLPAKPFGPYEEGGNEEE"
     gene            complement(1223..1660)
                     /gene="dtd"
                     /locus_tag="RN951_002488"
     CDS             complement(1223..1660)
                     /gene="dtd"
                     /locus_tag="RN951_002488"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HDX2527471.1"
                     /translation="MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANR
                     LCERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRA
                     EALYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV"
     gene            complement(1657..2529)
                     /locus_tag="RN951_002489"
     CDS             complement(1657..2529)
                     /locus_tag="RN951_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor BrkB family protein"
                     /protein_id="HDX2527472.1"
                     /translation="MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSL
                     LSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMT
                     AVGACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAI
                     SSYLLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAA
                     LLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYR
                     KLKQAAEQEEDDEP"
     gene            complement(2523..3122)
                     /gene="yihX"
                     /locus_tag="RN951_002490"
     CDS             complement(2523..3122)
                     /gene="yihX"
                     /locus_tag="RN951_002490"
                     /EC_number="3.1.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709685.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphatase"
                     /protein_id="HDX2527473.1"
                     /translation="MLYIFDLGNVIVDIDFNRVLGAWSDLTRIPLASLKKSFHMGEAF
                     HQHERGEISDEAFAEALCHEMALPLSYEQFSHGWQAVFVALRPEVIAIMHKLREQGHR
                     VVVLSNTNRLHTTFWPEEYPEIRDAADHIYLSQDLGMRKPEARIYQHVLQAEGFSPSD
                     TVFFDDNADNIEGANQLGITSILVKDKTTIPDYFAKVLC"
     gene            complement(3221..4006)
                     /locus_tag="RN951_002491"
     CDS             complement(3221..4006)
                     /locus_tag="RN951_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418320.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDX2527474.1"
                     /translation="MSLTELTGNPRHDQLLMLIAERGYMNIDELANLLDVSTQTVRRD
                     IRKLSEQGLITRHHGGAGRASSVVNTAFEQREVSQTEEKKAIAEAVADYIPDGSTIFI
                     TIGTTVEHVARALLNHNHLRIITNSLRVAHILYHNPRFEVMVPGGTLRSHNSGIIGPS
                     AASFVADFRADYLVTSVGAIESDGALMEFDVNEANVVKTMMAHARNILLVADHTKYHA
                     SAAVEIGNVAQVTALFTDELPPAALKSRLQDSQIEIILPQEDA"
     gene            complement(4040..4936)
                     /gene="yihV"
                     /locus_tag="RN951_002492"
     CDS             complement(4040..4936)
                     /gene="yihV"
                     /locus_tag="RN951_002492"
                     /EC_number="2.7.1.184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418319.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfofructose kinase"
                     /protein_id="HDX2527475.1"
                     /translation="MIRVACVGITVMDRIYYVEGLPTESGKYVARNYTEVGGGPAATA
                     AVAAARLGAQVDFIGRVGDDDTGNSLLAELESWGVNTRYTKRYNQAKSSQSAIMVDTK
                     GERIIINYPSPDLLPDAEWLEEIDFSQWDVVLADVRWHDGAKKAFTLARQAGVMTVLD
                     GDITPQDISELVALSDHAAFSEPGLARLTGVKEMASALKQAQTLTNGHVYVTQGSAGC
                     DWLENGGRQHQPAFKVDVVDTTGAGDVFHGALAVALATSGDLAESVRFASGVAALKCT
                     RPGGRAGIPDCDQTRSFLSLFV"
     gene            5104..6000
                     /gene="yihU"
                     /locus_tag="RN951_002493"
     CDS             5104..6000
                     /gene="yihU"
                     /locus_tag="RN951_002493"
                     /EC_number="1.1.1.373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfolactaldehyde 3-reductase"
                     /protein_id="HDX2527476.1"
                     /translation="MAAIAFIGLGQMGSPMASNLLQQGHQLRVFDVNAEAVRHLVDKG
                     ATPAANPAQAAKDAEFIITMLPNGDLVRNVLFGENGVCEGLSTDALVIDMSTIHPLQT
                     DKLIADMQAKGFSMMDVPVGRTSANAITGTLLLLAGGTAEQVERATPILMAMGSELIN
                     AGGPGMGIRVKLINNYMSIALNALSAEAAVLCEALNLPFDVAVKVMSGTAAGKGHFTT
                     SWPNKVLSGDLSPAFMIDLAHKDLGIALDVANQLHVPMPLGAASREVYSQARAAGRGR
                     QDWSAILEQVRVSAGMTAKVKM"
     gene            6024..6902
                     /gene="yihT"
                     /locus_tag="RN951_002494"
     CDS             6024..6902
                     /gene="yihT"
                     /locus_tag="RN951_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfofructosephosphate aldolase"
                     /protein_id="HDX2527477.1"
                     /translation="MNKYTINDITRASGGFAMLAVDQREAMRMMFAAAGAPAPVADSV
                     LTDFKVNAAKALSPYASAILVDQQFCYRQVVEQNAIAKSCAMIVAADEFIPGNGIPVD
                     SVVIDRKINPLQIKQDGGKALKLLVLWRSDEDAQQRLDMVKEFNELCHSHGLVSIIEP
                     VVRPPRRGDKFDREQAIIDAAKELGDSGADLYKVEMPLYGKGPQQELLCASQRLNDHI
                     NMPWVILSSGVDEKLFPRAVRVAMTAGASGFLAGRAVWASVVGLPDNELMLRDVCAPK
                     LQQLGDIVDEMMAKRR"
     gene            6919..8160
                     /gene="yihS"
                     /locus_tag="RN951_002495"
     CDS             6919..8160
                     /gene="yihS"
                     /locus_tag="RN951_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418316.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfoquinovose isomerase"
                     /protein_id="HDX2527478.1"
                     /translation="MKWFNTLSHNRWLEQETDRIFDFGKNSVVPTGFGWLGNKGQIKE
                     EMGTHLWITARMLHVYSVAAAMGRPGAYSLVDHGIKAMNGALRDKKYGGWYACVNDEG
                     VVDASKQGYQHFFALLGAASAVTTGHPEARKLLDYTIEIIEKYFWSEEEQMCLESWDE
                     AFSKTEEYRGGNANMHAVEAFLIVYDVTHDKKWLDRAIRVASVIIHDVARNNHYRVNE
                     HFDTQWNPLPDYNKDNPAHRFRAFGGTPGHWIEWGRLMLHIHAALEARCEQPPAWLLE
                     DAKGLFNATVRDAWAPDGADGIVYTVDWEGKPVVRERVRWPIVEAMGTAYALYTVTGD
                     RQYETWYQTWWEYCIKYLMDYENGSWWQELDADNKVTTKVWDGKQDIYHLLHCLVIPR
                     IPLAPGMAPAVAAGLLDINAK"
     gene            8298..9200
                     /locus_tag="RN951_002496"
     CDS             8298..9200
                     /locus_tag="RN951_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709679.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose-1-epimerase"
                     /protein_id="HDX2527479.1"
                     /translation="MQITNMHCSGQTVSLAAGDYHATIVTVGAGLAELTFQGCHLVIP
                     HKPEEMPLAHLGKVLIPWPNRIANGCYRYQGQEYQLPINEHSSKAAIHGLLAWRDWQI
                     SELTATSVTLTAFLPPSYGYPFMLASQVVYSLNAHTGLSVEIASQNIGTVAAPYGVGI
                     HPYLTCNLTSVDEYLFQLPANQVYAVDEHANPTTLHHVDELDLNFTQAKKIAATKIDH
                     TFKTANDLWEMTITHPQQALSVSLCSDQLWVQVYSGEKLQRQGLAVEPMSCPPNAFNS
                     GIDLLLLESGKPHRLFFNIYGQRK"
     gene            9399..11435
                     /gene="yihQ"
                     /locus_tag="RN951_002497"
     CDS             9399..11435
                     /gene="yihQ"
                     /locus_tag="RN951_002497"
                     /EC_number="3.2.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfoquinovosidase"
                     /protein_id="HDX2527480.1"
                     /translation="MDTSRPQLLDFQFHQNNDSFTLHFQQRLILTHSKDNPCLWIGSG
                     IADIDMFRGNFSIKDKLQEKIALTDAIVSQSPDGWLIHFSRGSDISATLNISADDQGR
                     LLLELQNDNLNHNRIWLRLAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQ
                     TYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALW
                     EDKATLRFECADTYISLLEKLTALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMR
                     NAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSENYPQLDSRIKQWNQEGVQFLAYI
                     NPYVASDKDLCEEAAQHGYLAKDASGGDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKK
                     NMIELGCGGWMADFGEYLPTDTYLHNGVSAEIMHNAWPALWAKCNYEALEETGKLGEI
                     LFFMRAGSTGSQKYSTMMWAGDQNVDWSLDDGLASVVPAALSLAMTGHGLHHSDIGGY
                     TTLFEMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFARMTTVFT
                     TLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAHTYTLKYQYLLGRDILVAPVHEEGRS
                     DWTLYLPEDNWVHAWTGEAFRGGEVTVNAPIGKPPVFYRADSEWAALFASLKSI"
     gene            11481..12866
                     /locus_tag="RN951_002498"
     CDS             11481..12866
                     /locus_tag="RN951_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418313.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2527481.1"
                     /translation="MSHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFY
                     TDVLGLPGTYGGIIFLISKFFTAFTDMGTGIMLDSRRKIGPKGKFRPFILYASFPVTL
                     LAIANFVGTPFDVTGKTVMATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAW
                     RQGGATLGLLLCTVGFVPVMNLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYV
                     ETQPANPAQKPGLLQSFRAIAGNRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDP
                     ILLSYMGFFSMGCIFIGVFLMPASVRRFGKKKVYIGGLLIWVLGDLLNYFFGGGSVSF
                     VAFSCLAFFGSAFVNSLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQALAGF
                     FPGWMLTQIGYVPNVAQADHTIEGLRQLIFIYPSALAVVTIVAMGCFYSLNEKMYVRI
                     VEEIEARKRTA"
     gene            12909..14312
                     /locus_tag="RN951_002499"
     CDS             12909..14312
                     /locus_tag="RN951_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2527482.1"
                     /translation="MSDHNPLTLKLNLREKIAYGMGDVGSNLMLCIGTLYLLKFYTDE
                     LGMPAYYGGIIFLVAKFFTAFTDMLTGFLLDSRKNIGPKGKFRPFILYAAVPAALIAT
                     LQFIATTFCLPVKTTIATALFMMFGLSYSLMNCSYGAMIPAITKNPNERAQLAAYRQG
                     GATIGLLICTVAFIPLQSLFSDSTVGYACAALMFSIGGFIFMMLCYRGVKEHYVDTTP
                     TGHKASILKSFCAIFRNPPLLVLCIANLCTLAAFNIKLAIQVYYTQYVLNDINLLSWM
                     GFFSMGCILIGVLLVPLTVKCFGKKQVYLAGMVLWAVGDILNYFWGSNSFTFVMFSCV
                     AFFGTAFVNSLNWALVPDTVDYGEWKTGIRAEGSVYTGYTFFRKISAALAGFLPGIML
                     TQIGYVPNIAQSDATLQGLRQLIFIWPCALAIIAALTMGFFYTLNEKRFALIIEEINQ
                     RKNKEMATEEKTASVTL"
     gene            14380..15072
                     /gene="ompL"
                     /locus_tag="RN951_002500"
     CDS             14380..15072
                     /gene="ompL"
                     /locus_tag="RN951_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpL"
                     /protein_id="HDX2527483.1"
                     /translation="MKKINAIILLSSLTSASVFAGAYVENREAYNLASDQGEVMLRVG
                     YNFDMGAGIMLTNTYNFQREDELKHGYNEIEGWYPLFKPTDKLTIQPSGLINDKSIGS
                     GGAVYLDVNYKFVPWFNLTVRNRYNHNNYSSTDLSGELDNNDTYEIGTYWNFKITDKF
                     SYTFEPHYFMRVNDFNSSNGKDHHWEITNTFRYRINEHWLPYFELRWLDRNVEPYHRE
                     QNQIRIGTKYFF"
     gene            complement(15163..16428)
                     /locus_tag="RN951_002501"
     CDS             complement(15163..16428)
                     /locus_tag="RN951_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2527484.1"
                     /translation="MLTKKKWALFSLLTLCGGTIYKLPSLKDAFYIPMQEYFHLTNGQ
                     IGNAMSVNSFVTTVGFFLSIYFADKLPRRYTMSFSLIATGLLGVYLTTMPGYWGILFV
                     WALFGVTCDMMNWPVLLKSVSRLGNSEQQGRLFGFFETGRGIVDTVVAFSALAVFTWF
                     GSGLLGFKAGIWFYSLIVIAVGIIIFFVLNDKEEAPSVEVKKEDGASKNTSMTSVLKD
                     KTIWLIAFNVFFVYAVYCGLTFFIPFLKNIYLLPVALVGAYGIINQYCLKMIGGPIGG
                     MISDKILKSPSKYLCYTFIISTAALVLLIMLPHESMPVYLGMACTLGFGAIVFTQRAV
                     FFAPIGEAKIAENKTGAAMALGSFIGYAPAMFCFSLYGYILDLNPGIIGYKIVFGIMA
                     CFAFSGAVVSVMLVKRISQRKKEMLAAEA"
     gene            complement(16530..17510)
                     /locus_tag="RN951_002502"
     CDS             complement(16530..17510)
                     /locus_tag="RN951_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HDX2527485.1"
                     /translation="MVTINNARKILQRVDTLPLYLHAYAFHLNMRLERVLPADLLDIA
                     SENNLRGVKIHVLDGERFSLGNMDDKELSAFGDKARRLNLDIHIETSASDKASIDEAV
                     AIALKTGASSVRFYPRYEGNLRDVLSIIANDIAYVRETYQDSGLTFTIEQHEDLKSHE
                     LVSLVKESEMESLSLLFDFANMINANEHPIDALKTMAPHITQVHIKDALIVKEPGGLG
                     HKACISGQGDMPFKALLTHLICLGDDEPQVTAYGLEEEVDYYAPAFRFEDEDDNPWIP
                     YRQMSETPLPENHLLDARLRKEKEDAINQINHVRNVLQQIKQEANHLLNH"
     gene            complement(17518..18228)
                     /locus_tag="RN951_002503"
     CDS             complement(17518..18228)
                     /locus_tag="RN951_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
                     /protein_id="HDX2527486.1"
                     /translation="MAENQSTVENAKEKLDRWLKDGITTPGGKLPSERELGELLGIKR
                     MTLRQALLNLEAESKIFRKDRKGWFVTQPRFNYSPELSASFQRAAIEQGREPSWGFTE
                     KNRTSDIPETLAPLIAVTPSTELYRITGWGALEGHKVFYHETYINPEVAPGFIEQLEN
                     HSFSAVWEKCYQKETVVKKLIFKPVRMPGDISKYLGGSAGMPAILIEKHRADQQGNIV
                     QIDIEYWRFEAVDLIINL"
     gene            complement(18445..20268)
                     /gene="typA"
                     /locus_tag="RN951_002504"
     CDS             complement(18445..20268)
                     /gene="typA"
                     /locus_tag="RN951_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-dependent GTPase TypA"
                     /protein_id="HDX2527487.1"
                     /translation="MIEKLRNIAIIAHVDHGKTTLVDKLLQQSGTFDSRAETQERVMD
                     SNDLEKERGITILAKNTAIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAF
                     DGPMPQTRFVTKKAFAYGLKPIVVINKVDRPGARPDWVVDQVFDLFVNLDATDEQLDF
                     PIVYASALNGIAGLDHEDMAEDMTPLYQAIVDHVPAPDVDLDGPFQMQISQLDYNSYV
                     GVIGIGRIKRGKVKPNQQVTIIDSEGKTRNAKVGKVLGHLGLERIETDLAEAGDIVAI
                     TGLGELNISDTVCDTQNVEALPALSVDEPTVSMFFCVNTSPFCGKEGKFVTSRQILDR
                     LNKELVHNVALRVEETEDADAFRVSGRGELHLSVLIENMRREGFELAVSRPKVIFREI
                     DGRKQEPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIG
                     FRSEFMTMTSGTGLLYSTFSHYDDVRPGEVGQRQNGVLISNGQGKAVAFALFGLQDRG
                     KLFLGHGAEVYEGQIIGIHSRSNDLTVNCLTGKKLTNMRASGTDEAVVLVPPIRMTLE
                     QALEFIDDDELVEVTPTSIRIRKRHLTENDRRRANRAPKDD"
     gene            20641..22050
                     /gene="glnA"
                     /locus_tag="RN951_002505"
     CDS             20641..22050
                     /gene="glnA"
                     /locus_tag="RN951_002505"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--ammonia ligase"
                     /protein_id="HDX2527488.1"
                     /translation="MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFF
                     EEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYD
                     RDPRSIAKRAEDYLRSTGIADTVLFGPEPEFFLFDDIRFGSSISGSHVAIDDIEGAWN
                     SSTQYEGGNKGHRPAVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAG
                     QNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLS
                     KNGVNLFAGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPGYEAPVMLA
                     YSARNRSASIRIPVVSSPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEA
                     MDKNLYDLPPEEAKEIPQVAGSLEEALNELDLDREFLKAGGVFTDEAIDAYIALRREE
                     DDRVRMTPHPVEFELYYSV"
     gene            22336..23385
                     /gene="glnL"
                     /locus_tag="RN951_002506"
     CDS             22336..23385
                     /gene="glnL"
                     /locus_tag="RN951_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(II)"
                     /protein_id="HDX2527489.1"
                     /translation="MATGTQPDAGQILNSLINSILLIDDNLAIHYANPAAQQLLAQSS
                     RKLFGTPLPELLSYFSLNIELMQESLEAGQGFTDNEVTLVIDGRSHILSVTAQRMPDG
                     MILLEMAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALP
                     DPSLLEYTKVIIEQADRLRNLVDRLLGPQLPGTRVTESIHKVAERVVTLVSMELPDNV
                     RLIRDYDPSLPELAHDPDQIEQVLLNIVRNALQALGPEGGEIILRTRTAFQLTLHGER
                     YRLAARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHSGKIEFTS
                     WPGHTEFSVYLPIRK"
     gene            23397..24806
                     /gene="glnG"
                     /locus_tag="RN951_002507"
     CDS             23397..24806
                     /gene="glnG"
                     /locus_tag="RN951_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(I)"
                     /protein_id="HDX2527490.1"
                     /translation="MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGAEVLEALA
                     SKTPDVLLSDIRMPGMDGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYL
                     PKPFDIDEAVALVERAISHYQEQQQPRNVQLNGPTTDIIGEAPAMQDVFRIIGRLSRS
                     SISVLINGESGTGKELVAHALHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFT
                     GANTIRQGRFEQADGGTLFLDEIGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRI
                     IAATHQNLEQRVQEGKFREDLFHRLNVIRVHLPPLRERREDIPRLARHFLQVAARELG
                     VEAKLLHPETEAALTRLAWPGNVRQLENTCRWLTVMAAGQEVLIQDLPGELFESTVAE
                     STSQMQPDSWATLLAQWADRALRSGHQNLLSEAQPELERTLLTTALRHTQGHKQEAAR
                     LLGWGRNTLTRKLKELGME"
     gene            24918..25028
                     /locus_tag="RN951_002508"
     CDS             24918..25028
                     /locus_tag="RN951_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YshB family small membrane protein"
                     /protein_id="HDX2527491.1"
                     /translation="MLESIINLVSSGAVDSHTPQTAVAAVLCAAMIGLFS"
     gene            complement(25257..26630)
                     /gene="hemN"
                     /locus_tag="RN951_002509"
     CDS             complement(25257..26630)
                     /gene="hemN"
                     /locus_tag="RN951_002509"
                     /EC_number="1.3.98.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312816.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HDX2527492.1"
                     /translation="MSVQQIDWDLALIQKYNYSGPRYTSYPTALEFSEDFGEQAFLQA
                     VARYPERPLSLYVHIPFCHKLCYFCGCNKIVTRQQHKADQYLDALEQEIVHRAPLFAG
                     RHVSQLHWGGGTPTYLNKAQISRLMKLLRENFQFNADAEISIEVDPREIELDVLDHLR
                     AEGFNRLSMGVQDFNKEVQRLVNREQDEEFIFALLNHAREIGFTSTNIDLIYGLPKQT
                     PESFAFTLKRVAELNPDRLSVFNYAHLPTIFAAQRKIKDADLPSPQQKLDILQETIAF
                     LTQSGYQFIGMDHFARPDDELAVAQREGVLHRNFQGYTTQGDTDLLGMGVSAISMIGD
                     CYAQNQKELKQYYQQVDEQGNALWRGIALTRDDCIRRDVIKSLICNFRLDYAPIEKQW
                     DLHFADYFAEDLKLLAPLAKDGLVDVDEKGIQVTAKGRLLIRNICMCFDTYLRQKARM
                     QQFSRVI"
     gene            complement(26819..27328)
                     /gene="yihI"
                     /locus_tag="RN951_002510"
     CDS             complement(26819..27328)
                     /gene="yihI"
                     /locus_tag="RN951_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Der GTPase-activating protein YihI"
                     /protein_id="HDX2527493.1"
                     /translation="MKPSSSNSRSKGHAKARRKTREELDQEARDRKRQKKRRGHAPGS
                     RAAGGNTTSGSKGQNAPKDPRIGSKTPIPLGVTEKVTKQHKPKSEKPMLSPQAELELL
                     ETDERLDALLERLEAGETLSAEEQSWVDAKLDRIDELMQKLGLSYDDDEEEEEDEKQE
                     DMMRLLRGN"
     gene            27910..28542
                     /locus_tag="RN951_002511"
     CDS             27910..28542
                     /locus_tag="RN951_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418301.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HDX2527494.1"
                     /translation="MTNLNYQQTHFVMSAPDIRHLPSDTGIEVAFAGRSNAGKSSALN
                     TLTNQKSLARTSKTPGRTQLINLFEVADGKRLVDLPGYGYAEVPEEMKRKWQRALGEY
                     LEKRQSLQGLVVLMDIRHPLKDLDQQMIEWAVDSNIAVLVLLTKADKLASGARKAQLN
                     MVREAVLAFNGDVQVETFSSLKKQGVDKLRQKLDTWFSEMQPVEETQDGE"
     gene            complement(28923..31709)
                     /gene="polA"
                     /locus_tag="RN951_002512"
     CDS             complement(28923..31709)
                     /gene="polA"
                     /locus_tag="RN951_002512"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HDX2527495.1"
                     /translation="MVQIPQNPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLN
                     MLRSLIMQYKPTHAAVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAM
                     GLPLLAVSGVEADDVIGTLAREAEKAGRPVLISTGDKDMAQLVTPNITLINTMTNTIL
                     GPEEVVNKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEP
                     EKIAGLSFRGAKTMAAKLEQNKEVAYLSYQLATIKTDVELELTCEQLEVQQPAAEELL
                     GLFKKYEFKRWTADVEAGKWLQAKGAKPAAKPQETSVADEAPEVTATVISYDNYVTIL
                     DEETLKAWIAKLEKAPVFAFDTETDSLDNISANLVGLSFAIEPGVAAYIPVAHDYLDA
                     PDQISRERALELLKPLLEDEKALKVGQNLKYDRGILANYGIELRGIAFDTMLESYILN
                     SVAGRHDMDSLAERWLKHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQL
                     HLKMWPDLQKHKGPLNVFENIEMPLVPVLSRIERNGVKIDPKVLHNHSEELTLRLAEL
                     EKKAHEIAGEEFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLP
                     KVILEYRGLAKLKSTYTDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVR
                     NEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRDKGLLTAFAEGKDIHRATAAE
                     VFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGV
                     LEYMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGARRAAAERAAINAPMQGTAADII
                     KRAMIAVDAWLQAEQPRVRMIMQVHDELVFEVHKDDVDAVAKQIHQLMENCTRLDVPL
                     LVEVGSGENWDQAH"
     gene            32073..33005
                     /locus_tag="RN951_002513"
     CDS             32073..33005
                     /locus_tag="RN951_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HDX2527496.1"
                     /translation="MANLLNKFIMTRILAAITLLLSIVLTILVTIFCSVPIIIAGIVK
                     LLLPVPVIWRKVSRFCDFMMYCWCEGLAVLLHLNPHLQWEVHGLEGLSKKNWYLLICN
                     HRSWADIVVLCVLFRKHIPMNKYFLKQQLAWVPFLGLACWSLDMPFMKRYSRAYLLRH
                     PERRGKDVETTRRSCEKFRLHPTTIVNFVEGSRFTQEKHQQTHSTFQNLLPPKAAGIA
                     MALNVLGKQFDKLLNVTLCYPDNNRQPFFDMLSGKLTRIVVHVDLQPIADELHGDYIN
                     DKSFKRHFQQWLNSLWQEKDRLLTSLMSSQRQNK"
     gene            complement(33046..34476)
                     /locus_tag="RN951_002514"
     CDS             complement(33046..34476)
                     /locus_tag="RN951_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418298.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgA family protein"
                     /protein_id="HDX2527497.1"
                     /translation="MIRKSATGVIVALAVIWGGGTWYTGTQIQPGVEKFIKDFNDAKK
                     KGEHAYDMTLSYQNFDKGFFNSRFQMQMTFDNGAPDLNIKPGQKVVFDVDVEHGPLPI
                     TMLMHGNVIPALAAAKVNLVNNELTQPLFIAAKNKSPVEATLRFAFGGSFSTTLDVAP
                     AEYGKFSFGEGQFTFNGDGSSLSNLDIEGKVEDIVLQLSPMNKVTAKSFTIDSLARLE
                     EKKFPVGESESKFNQINIINHGEDVAQIDAFVAKTRLDRVKDKDYINVNLTYELDKLT
                     KGNQQLGSGEWSLIAESIDPSAVRQFIIQYNIAMQKQLAAHPELANDEVALQEVNAAL
                     FKEYLPLLQKSEPTIKQPVRWKNALGELNANLDISIADPAKSSSSTNKDIKSLNFDVK
                     LPLNVVTETAKQLNLSEGMDAEKAQKQADKQISGMMTLGQMFQLITIDNNTASLQLRY
                     TPGKVVFNGQEMSEEEFMSRAGRFVH"
BASE COUNT         8423 a         8827 c         8453 g         8824 t
ORIGIN      
        1 gactatcaaa aatcgctcaa acatgaacta agatgatgaa ttaagcatta tctgcgataa
       61 ttgccactca gttctacaaa taatatttaa atgctcctga acagtgatgt agcaagacac
      121 gtatggagcc aacgaagaat aaaaatttat agagttctta tttaatataa ccgaaatagc
      181 caaggactaa tataaatgac ctgaatgaga gaggcagcac cgcccctctc catcagctac
      241 tcttcttcgt tcccgccctc ttcatacggg ccaaatggct tcgcgggcag aacgatatac
      301 gtgccttcaa acactgcacc cggcgtctcg tcgccaaaga tttcgacctg catctgcacc
      361 cgtgcttttc gtccgcgcgc cagacggtcg agatcgccgc ttaaggcacc gaggtcggct
      421 accgcatgag gtttaccgct aatcggcttg ctgtagcgga tatgcgcatc cgcaagaata
      481 atcgttccgc cgaggtggcg ttcacgcagc atcagccaga taagtcccca accggtgagc
      541 gtcgccagtg agaataaact cccggcaaac agcgtatggt gcggattctg attgccggtt
      601 tctggcatgg tagtgataaa tttttgcccg gtatattgct gaatgcgcac gcccattttt
      661 tcactaagcg ggatatgttc gtaccacgcc tgttgcagct gcgcgcacca gtcgccgcga
      721 tgcagaatgt catccagagt ggcgacgggc ttaatcatca aaaaatggcg aatcggcgtg
      781 gtggttggcg tggtgatttc tccctgatta acaaacccca gcttggcgaa aaactccacc
      841 gcgtcttcac gggcgctaca ggtcacgcgc ttaacgcctt cctgacgcgc caccgactcc
      901 agggtcatcg ccatcagcgt gcctaaccct ttgtcctgca cgtcgggatg aacggccata
      961 aagcgaatgg acgcttcatt gtcggcatta atatacagtc ggcctaccgc caccagatta
     1021 ccctgctcgt cgacgaccat ctggtgatgc gccatcgcat cccacgcgtc gcgttccgaa
     1081 ccttttggtt gatgcagggg cttacgcaac atttcccagc gaaactgata gtaacgctct
     1141 aattcttctt ctgtttgtgg aacccgaagg tgatacatag cgatactctc tcttgtttcc
     1201 cgtgacaacc ctggaagctg gctcatacct gcaaccagaa tgtcacgggg ccatcattga
     1261 ccagcgatac ctgcatatcc gcagcgaagc gtcctgtttg cgtgttcatc tcttgctgac
     1321 ggcagcgttc gacgaaatag tcatataacg cctctgcgcg atccggtgat gcacctttgg
     1381 agaaacttgg gcgcatcccc cgttcggtat ctgcggcgag ggtaaactgg gaaaccacca
     1441 gcacactgcc gcccgcctgt tgcacgttga gattcatctt gccttcggca tcgctaaaga
     1501 tgcggtagcc gagcacacgc tcgcacagac ggtttgcttt ctgttcgtcg tcatcctttt
     1561 cgacacccaa taacaccaaa agtcccgcgc caatttcgcc cgtcacttct ccctccacgg
     1621 tgacgctggc acgggttacg cgttgaatta atgcaatcat ggttcgtcgt cttcttcttg
     1681 ttcagctgct tgttttagtt tgcggtattc cccgagagtg acagtaattt ccgcgccaag
     1741 caagacgata caccatgtcc agtagaccca aacaaagaga atggggatca ccgccagcac
     1801 accataaatg agctgatatg acgggaacat ggtgatataa agcgcgaaac ctttctttcc
     1861 tgcttcgaac aggagtgcgg cgacaaacgc gccaacaatc gcgtcgcggt taggtacgcg
     1921 gatggtagga acaatgctgt acagcaacca gaaggagatc cacgacaaca gcaacggaaa
     1981 aatacgcagc acgttgtcga tgacagtatt gagatcgctc gcccagcgca gggagagcaa
     2041 ataggaactg atcgccagac tggcccctgc cagcagcggc cccagcgtta aaatcatcca
     2101 gtacacggcg aacgagtaaa tttttggtcg cgctcgttta ctgcgccaga tggtattcaa
     2161 cgcgctatcg atggagtaca tcaacaataa cgcggtgacg atcagcccgc acgccccaac
     2221 ggcggtcatc ttgttggaat tggcaacaaa ttgttcgata taccgctgaa taacatcgcc
     2281 agtagcaggc agaaagttgg caaaaataaa gtgacgtaac tgaatgctga cgtcggaaaa
     2341 catgggaaaa gcggcgaaaa gcgcaaaaac aacggcaacc agcggcacta atgagagcaa
     2401 cgacacatag gcaaggttac ctgccagggt tgtcatgttg tcctcatcaa tgcgttgcca
     2461 gagtagtttt agccaggccc atagtggacg ggtacggtgc ctggctttgt cctgaatggt
     2521 ttttagcata acaccttcgc gaaatagtcc gggatggtgg ttttatcttt caccagaata
     2581 ctggtaatgc ccagctgatt ggctccttct atattatcgg cgttatcgtc gaaaaagacc
     2641 gtatcgctgg gtgaaaaacc ttccgcctgc aaaacatgct ggtaaattcg tgcttcaggt
     2701 ttgcgcatcc ccagatcttg cgacagatag atatggtcag cagcatcacg aatttccggg
     2761 tattcttccg gccagaaggt ggtatgcagg cggttggtat tggaaagcac caccacgcga
     2821 tgcccctgct cacgcagttt atgcatgatg gcgatcactt ccgggcgcag cgcaacaaac
     2881 accgcctgcc agccgtgaga gaactgctcg tagcttagcg gtagagccat ctcatgacac
     2941 agcgcctctg cgaacgcttc gtcgctaatt tccccacgct catgctgatg aaacgcctcc
     3001 cccatatgaa aactcttctt aagcgatgcc agcggaatac gcgttaaatc gctccaggct
     3061 cccagcacac ggttaaagtc gatatcgaca atcacattac ctaaatcaaa gatatagagc
     3121 atttttgcct cctttcgcgc cacaagaaat taactgtagc gggaaaggat gggtttggct
     3181 atgtggcaag gtatgaagcc aggttaacgg tcacaaaaat ctacgcgtct tcctggggaa
     3241 gaatgatttc aatttggctg tcttgtaagc gtgattttag cgcagcgggc ggcagctcgt
     3301 cggtaaagag cgcagtgacc tgtgccacgt taccaatttc aaccgccgcc gaagcatgat
     3361 acttagtgtg atcggcgacc agcagaatat ttctcgcgtg cgccatcatc gttttcacca
     3421 cgttagcttc gtttacatca aactccatca acgcgccatc gctctcaatc gccccaacgc
     3481 ttgttaccag ataatcagca cgaaaatcag ccacaaagga cgccgctgaa gggccaatga
     3541 tcccgctatt atgagagcgc aacgtaccgc cgggcaccat cacttcaaag cgcgggttgt
     3601 ggtaaagaat atgcgccaca cgcaggctgt tggtgattat ccgcaaatga ttatggttaa
     3661 gtaacgcccg ggcaacatgc tcaacagtcg taccaatggt gataaatatt gttgaaccat
     3721 caggaatata gtctgccacc gcttcggcaa tcgctttttt ttcctcggtt tgcgaaacct
     3781 cacgctgctc gaacgccgta ttaacgacgc tggaagcccg acccgcgcca ccgtgatggc
     3841 gcgtaatcag gccttgctcg cttaatttac gaatatcccg gcggaccgtc tgcgtggaga
     3901 catccagcag atttgccagc tcatcaatat tcatataccc acgctcggcg atcagcatga
     3961 ggagttggtc gtgccgcggg ttaccggtta gttcggtaag gctcatgaaa attcctcgaa
     4021 aaaccatcac cctggcattt tatacaaaaa gtgacaaaaa agatcgggtt tgatcacagt
     4081 cagggatccc ggctcgtcca ccgggacgtg tgcattttaa cgccgctaca ccgctggcga
     4141 agcggactga ctccgctaaa tccccacttg ttgccagcgc caccgccaaa gcgccgtgaa
     4201 aaacatcacc cgcacctgtg gtatctacca catcaacttt gaaggccggt tgatgctgac
     4261 gcccaccatt ttccagccag tcgcagcctg cgctaccctg ggtcacatag acatgaccat
     4321 ttgtgagcgt ttgtgcctgt tttagcgcac tggccatctc tttcacgccc gttaagcgcg
     4381 ccagacccgg ttctgaaaag gccgcgtgat cgcttaatgc caccagctca ctgatatcct
     4441 gcggcgtaat gtccccgtcc agaacggtca tcacacccgc ctgacgggcc agggtgaagg
     4501 cttttttagc gccgtcgtgc cagcgtacat ctgccagcac aacatcccac tgagagaaat
     4561 caatttcctc caaccactct gcgtcaggca gcagatccgg gctggggtag ttaatgatta
     4621 tccgctcgcc tttggtatcc accatgatgg cggattgcga agatttcgcc tggttatacc
     4681 gtttggtgta acgggtgtta acgccccagg attccagctc tgccagcagg ctgttgcccg
     4741 tgtcgtcatc acctacgcga ccaataaaat cgacctgcgc ccccagcctt gccgccgcaa
     4801 ccgctgccgt cgccgctggc ccgccaccaa cttccgtata atttctcgcc acgtatttac
     4861 cgctctccgt cggtaaccct tccacgtaat agatgcgatc catcacggtt atacctacac
     4921 aagcaacacg aatcatggtc attccttaaa cattttggga tgcgttcatt ttaatttcac
     4981 caattgttta aaaagtgacg gctgtcaatt ttttgacgat aaattacaaa tacgatcaaa
     5041 aacagacaag caaagcatgt cataaatgac aaaaagtgac atcactgtat tcaggagagg
     5101 gttatggcag caatcgcgtt tatcggttta ggacaaatgg gttcgccaat ggcgagcaat
     5161 ttattgcagc aagggcatca acttcgcgtc tttgatgtga acgccgaagc tgtgcggcat
     5221 ctggtagaca aaggtgcgac tcccgccgcc aacccggcgc aggccgctaa agatgccgaa
     5281 tttatcatta ccatgttgcc gaatggcgat ctggtgcgca acgtgttgtt cggtgaaaac
     5341 ggcgtttgcg aaggcttatc taccgatgcg ctggtcattg atatgtccac catccatccg
     5401 ctgcaaaccg ataaattgat tgccgatatg caagccaaag gcttcagcat gatggatgtt
     5461 ccggtaggcc gtacttctgc aaatgccatt accggtactc tgttactgct ggctggcggc
     5521 accgctgaac aagttgaacg tgccacaccg atcctgatgg cgatgggcag tgagttgatc
     5581 aacgctggcg gtccgggcat ggggatccgc gttaagctca tcaacaacta catgagcatc
     5641 gcgctcaatg cgctttcggc agaagccgcc gttttgtgcg aagccctgaa tcttcccttc
     5701 gatgttgccg tcaaagtgat gagcggtacc gccgccggta aaggtcactt caccacttcc
     5761 tggccaaaca aagtcctcag cggagatctt tctcccgcct tcatgatcga tcttgcccat
     5821 aaggatcttg gcatcgccct tgatgtcgcc aaccagctgc atgtgccaat gccgctgggg
     5881 gccgcctcac gggaggttta tagccaggcg cgcgcagcgg gtcgcggtcg ccaggactgg
     5941 tccgccattc tggaacaggt ccgtgtcagt gccgggatga ctgccaaagt aaaaatgtaa
     6001 cgactggata aaggaataaa tgaatgaata agtacaccat caacgacatt acgcgcgcat
     6061 cgggcggttt tgccatgctg gcggtcgatc agcgcgaagc catgcgcatg atgtttgccg
     6121 cggctggggc acccgctccg gtagccgata gcgttttaac tgatttcaaa gttaacgctg
     6181 caaaggccct ctcgccttat gcctcggcga ttctggtaga tcaacaattc tgctaccgcc
     6241 aggtggttga gcaaaacgcg attgccaaaa gttgcgccat gattgtcgcc gccgatgagt
     6301 tcattcctgg caacggtatt ccggtcgata gcgtggttat tgaccgcaaa atcaatccgc
     6361 tacagatcaa acaagacggt ggcaaagcct taaaactgct ggtgctgtgg cgtagtgatg
     6421 aagatgcgca gcaacgtctg gatatggtga aagagttcaa cgaactgtgc cactcacacg
     6481 gtctggtaag catcattgag ccagtcgtcc gcccaccgcg tcgtggcgat aaattcgatc
     6541 gcgaacaagc gatcatcgat gccgccaaag agctgggcga cagtggcgct gacctctaca
     6601 aagttgaaat gccgctttat ggcaaaggtc cgcaacaaga gcttctctgt gcttcacaac
     6661 gtctgaatga ccatatcaat atgccatggg tgatcctctc ttccggtgtc gacgaaaaac
     6721 tgttcccgcg tgccgtacgc gtggcaatga cggcgggcgc atcgggattc ctggcaggcc
     6781 gtgcagtctg ggcatcggtc gtcggtttac cagacaacga gctgatgctg cgtgacgttt
     6841 gcgcaccgaa attacaacaa cttggcgata tcgtcgacga aatgatggct aaacgccgct
     6901 aagatgagga taaaaggaat gaaatggttt aacaccctaa gccacaaccg ttggctggaa
     6961 caggaaaccg accgcatctt tgattttggt aaaaattccg tagtgccgac tggttttggc
     7021 tggttaggca ataaagggca aatcaaagaa gagatgggca cccatctgtg gatcaccgct
     7081 cgtatgttgc acgtttattc cgttgctgcg gcgatgggtc gacctggcgc ttactcgttg
     7141 gttgatcacg gtatcaaagc catgaacggc gcactgcgtg ataaaaaata tggcggctgg
     7201 tatgcctgcg tgaatgacga gggcgtggtg gatgcctcca aacagggcta tcaacacttc
     7261 tttgctctgc tgggtgccgc cagcgccgtc acaacgggtc acccggaagc gcgcaagctg
     7321 ctcgattaca ccattgaaat tatcgagaaa tatttctgga gcgaagaaga gcagatgtgc
     7381 ctggaatcct gggacgaagc cttcagcaaa accgaagagt accgcggcgg caatgccaat
     7441 atgcacgcgg tggaagcttt cttgattgtt tatgacgtca ctcacgacaa aaaatggctg
     7501 gatcgcgcga ttcgcgtggc ttccgtgatt atccacgacg tcgccagaaa taatcattat
     7561 cgcgttaacg aacacttcga tacccagtgg aatccgctgc cggattacaa caaagataac
     7621 ccggcgcatc gcttccgcgc gttcggaggt acaccaggcc actggatcga atggggccgt
     7681 ttaatgctgc acatccatgc tgccctggaa gcccgttgcg aacaaccacc agcatggctg
     7741 ctagaagatg ccaaaggtct atttaacgcc accgtgcgcg atgcctgggc acccgatggc
     7801 gcggacggga ttgtttatac cgttgactgg gaaggaaaac cggtggtccg cgaacgtgta
     7861 cgttggccta tcgtcgaagc aatgggtacg gcctacgcgc tctacaccgt cactggcgat
     7921 cgccagtatg aaacctggta tcaaacatgg tgggagtact gcattaagta cctgatggac
     7981 tatgaaaatg gttcctggtg gcaggagctg gatgcggaca ataaggtcac caccaaagtc
     8041 tgggacggca aacaggatat ttatcacctg ctgcattgcc tggtgatccc gcgtatcccg
     8101 ttagcgcccg gcatggctcc agcggttgca gcgggtctgc tggatattaa tgcgaaataa
     8161 ctgatctgaa aatagggtgc gggttttccc ctctccctaa ccctctcccc aaaggggcga
     8221 ggggaccgtc cggtgcagtt tttgggtttg acatcagcct cacgggaggc tgtatgtcgt
     8281 taattaaggt gccttgtatg caaatcacca atatgcattg cagtggacag accgtttcac
     8341 ttgccgcggg ggattatcac gcgaccattg tgaccgtcgg tgctggtctg gctgaattaa
     8401 cctttcaggg ttgtcattta gtcatcccgc acaaacccga agagatgccg ctggcgcatc
     8461 tgggtaaagt gcttattccg tggccgaacc ggatcgccaa cggctgttac cgctatcagg
     8521 ggcaggaata tcagttaccc attaatgaac atagttcaaa agccgctatt cacgggctgc
     8581 ttgcctggcg agactggcaa attagtgaat taaccgccac cagcgttacc ctgacagctt
     8641 ttctgccgcc cagttacggc tatccgttta tgctggcttc acaagttgtt tattcgctca
     8701 acgcacacac gggtctttcc gttgagatcg caagccagaa tatcggcact gtcgcagcgc
     8761 cttatggcgt gggtattcat ccttatttaa cctgcaactt aacatctgtt gatgaatatc
     8821 tgttccagct tccggcaaac caggtttatg ccgtcgatga gcacgcgaat ccgacaacgc
     8881 ttcaccacgt tgatgagctg gatttaaatt tcacgcaggc gaaaaaaata gccgcgacaa
     8941 aaatcgacca cacctttaaa accgctaatg atttgtggga aatgaccatt acccatccac
     9001 agcaggcgct ttcggtaagc ctttgttccg atcaactctg ggtgcaggtt tatagcggtg
     9061 aaaaattaca gcgtcaggga ctggcagttg aacctatgag ttgcccgcct aacgccttta
     9121 attcaggtat cgacttatta ttactggaat caggaaaacc gcaccgcctg ttttttaata
     9181 tttacggaca gagaaaataa cttgtattga ttagcagtca aaatcattga agaacatttc
     9241 actcgctaaa ggcaacatta tgtatcttca atttattaag ttaaaaacag ctcagcttct
     9301 gtaaagtttt tatatatcag ttttatgaga atcattttac ataagcctgt aataacagga
     9361 aggcaacaat ctcgttctca actctatgga gattagttat ggatacgtca cgtccacagt
     9421 tattagattt tcaatttcat cagaataacg acagttttac cctacatttt caacaacgtc
     9481 ttattttaac ccatagcaaa gataatcctt gtttatggat tggctcaggt atagcggata
     9541 tcgatatgtt ccgcggtaat ttcagcatta aagataaact acaggagaaa attgcgctta
     9601 ccgacgccat cgtcagccag tcaccggatg gttggttaat tcatttcagc cgtggttctg
     9661 acattagcgc cacgctgaat atctctgccg acgatcaggg gcgtttattg ctggaactac
     9721 aaaacgacaa ccttaaccac aaccgtatct ggctgcgcct tgccgctcaa ccagaggacc
     9781 atatctacgg ctgcggcgaa cagttttcct acttcgatct gcgtggcaaa ccgttcccgc
     9841 tatggaccag tgaacaaggc gttggtcgca acaaacaaac ctatgtcacc tggcaggccg
     9901 actgcaaaga aaatgcgggc ggcgactatt actggacttt cttcccacag cctacgtttg
     9961 tcagcacgca gaagtattac tgccatgttg ataacagttg ctatatgaac ttcgacttta
    10021 gtgccccgga ataccatgaa ctggcgctgt gggaagacaa agcaacgctg cgttttgaat
    10081 gtgctgacac atacatttcc ctgctggaaa aattaaccgc cctgctggga cgccagccag
    10141 aactgcccga ctggatttat gacggagtaa cgctcggcat tcagggcggg acggaagtgt
    10201 gccagaagaa actggacacc atgcgtaacg cgggcgtgaa ggtcaacggc atctgggcgc
    10261 aggactggtc cggtattcgt atgacctctt ttggcaaacg cgtgatgtgg aactggaagt
    10321 ggaacagcga aaactacccg caactggatt cacgcattaa gcagtggaat caggagggcg
    10381 tgcagttcct ggcctatatc aacccgtatg ttgccagcga taaagatctc tgcgaagaag
    10441 cggcacaaca cggctatctg gcaaaagatg cctctggcgg tgactatctg gtggagtttg
    10501 gcgagtttta cggcggcgtt gtcgatctca ctaatccaga agcctacgcc tggttcaagg
    10561 aagtgatcaa aaagaacatg attgaactcg gctgcggcgg ctggatggct gacttcggcg
    10621 agtatctgcc caccgacacg tacctgcata acggcgtcag tgccgaaatt atgcataacg
    10681 cctggcctgc gctgtgggcg aagtgtaact acgaagccct tgaagaaacg ggcaagctcg
    10741 gcgagatcct tttctttatg cgcgccggtt ctaccggtag ccagaaatac tccaccatga
    10801 tgtgggcggg cgaccagaac gtcgactgga gtctcgacga tggcctggcg tcggttgtcc
    10861 cggcggcgct gtcgctggca atgaccggac atggcctgca ccacagcgac attggcggtt
    10921 acaccaccct gtttgagatg aagcgcagca aagagctgct gctgcgctgg tgcgatttca
    10981 gcgccttcac gccgatgatg cgcacccacg aaggtaaccg tcctggcgac aactggcagt
    11041 ttgacggcga cgcagaaacc atcgcccatt tcgcccgtat gaccaccgtc ttcaccaccc
    11101 tgaaacctta cctgaaagag gccgtcgcgc tgaatgcgaa gtccggcctg ccggttatgc
    11161 gcccgctgtt cctgcattac gaagacgatg cgcacactta caccctgaaa tatcagtacc
    11221 tgttaggtcg cgacattctg gtcgctccgg tgcatgaaga aggccgtagc gactggacgc
    11281 tctatctgcc ggaggataac tgggtccacg cctggacggg tgaagcgttc cggggcgggg
    11341 aagttaccgt taatgcgccc atcggcaagc cgccggtctt ttatcgcgcc gatagcgaat
    11401 gggcggcact gttcgcgtcg ttaaaaagca tctaatcaca tccgcccgtg gggaaactca
    11461 tgggcaaagg gagaacatcg atgagtcaca tcacaacgga agatccagca actttacgcc
    11521 tgccctttaa agagaaactc tcttacggta ttggcgacct ggcctctaac atcctgctgg
    11581 atatcggtac gctttatctt ttgaagtttt ataccgacgt tctggggctg ccaggcacct
    11641 atggcggcat tatctttttg atttcaaaat tctttactgc gtttaccgat atgggtaccg
    11701 gcattatgtt ggattcccga cgcaagatcg gtccaaaagg taagttccgt ccttttattc
    11761 tgtatgcgtc attcccggtc accttactgg cgatcgccaa ctttgtcggc acaccgtttg
    11821 atgtcaccgg taaaacggtg atggccacta ttctgtttat gctttacgga ctgtttttca
    11881 gcatgatgaa ctgctcctac ggcgcaatgg ttcccgctat caccaaaaac cccaacgaac
    11941 gcgcctcact ggcggcatgg cgtcagggcg gcgctacgct gggcctgctg ctgtgcacgg
    12001 tgggattcgt gccagttatg aatcttatcg aaggtaatca gcaacttggc tatatcttcg
    12061 ccgccacgct gttttcactg tttggcctgc tgtttatgtg gatctgctac tcgggcgtga
    12121 aagagcgtta tgtcgaaacc cagcctgcta atccggcgca aaagccgggc ctgctgcaat
    12181 ctttccgcgc aattgcgggt aaccgcccgc tgttcattct gtgcattgcc aacctctgca
    12241 ctttaggggc gtttaacgtc aagctcgcca tccaggtcta ttacacccag tacgtgctta
    12301 acgatcccat cctgttgtcg tatatgggat ttttcagcat gggctgtatt ttcatcggcg
    12361 tattcctgat gcctgcctca gtcagacgtt ttggcaagaa gaaagtttat atcggcggcc
    12421 tgctgatttg ggtgctgggc gatctgctca actatttctt cggcggcggt tcggtcagct
    12481 tcgtggcgtt ctcctgcctg gcgttctttg gctcagcgtt tgttaacagc ctgaactggg
    12541 cgctggtttc cgacaccgtc gagtacggcg agtggcgcac cggcgtgcgt tcggaaggaa
    12601 cggtctacac cggttttacc ttctttcgca aagtgtctca ggcgctggct ggtttcttcc
    12661 ccggctggat gctgacgcaa attggctatg tgccgaacgt cgcacaggct gaccacacca
    12721 ttgaagggtt acgccagttg atcttcatct acccaagcgc actggcggta gtcaccattg
    12781 tggcgatggg ttgcttctac agcctgaacg agaagatgta tgtccgcatt gtggaagaga
    12841 tagaagcccg taaacgcacg gcgtaataat aataaacgac gccctgcggg gcgttataag
    12901 gagtgattat gtctgaccat aatccactga cattaaaact gaatctgcgg gaaaaaatcg
    12961 cctatggtat gggcgacgtc ggttcgaatt taatgctctg catcggtact ctgtatctcc
    13021 tcaaatttta taccgatgaa ttagggatgc ctgcttacta tggcgggatt atctttctgg
    13081 tggcgaagtt ttttaccgcg tttaccgata tgctcaccgg atttttactc gactcgcgga
    13141 aaaatattgg gcctaaaggc aaatttcgtc cctttatttt atatgcagcg gttccggcgg
    13201 cgttaattgc aacgctccag tttatcgcca ccaccttttg tttgccggtt aaaacgacga
    13261 ttgccaccgc gctgtttatg atgtttggac tttcatacag tctgatgaac tgctcgtatg
    13321 gtgcgatgat cccggcaatt accaaaaacc cgaatgagcg cgcgcagctc gcggcttacc
    13381 gccagggtgg tgcaaccata gggctattga tttgtaccgt ggcgtttatt ccgttgcagt
    13441 cgcttttttc tgactcaacc gtcggttatg cctgtgcggc acttatgttc tccattggcg
    13501 gctttatttt tatgatgctg tgctacagag gcgtcaaaga gcattatgtg gacacaacgc
    13561 caaccggaca taaagccagt attctcaaat cattttgcgc gatatttcgg aatccgccat
    13621 tgctggtttt atgcattgct aacttgtgta ccctggcggc atttaatatc aaactggcga
    13681 ttcaggtcta ttacacccag tatgtgctga atgatattaa tttattgtcg tggatgggat
    13741 tcttcagtat gggatgcatc ctcatcggcg tattactggt gccattaact gtaaaatgtt
    13801 ttggtaaaaa acaggtttat ctggctggca tggtgctgtg ggcggtgggt gatatactga
    13861 attatttctg gggaagtaac tctttcactt tcgtcatgtt ctcttgtgtc gccttttttg
    13921 gcacggcctt tgtaaacagc ctgaactggg cactggtacc agataccgta gattacggtg
    13981 aatggaaaac cggtattcgt gccgaaggtt ctgtttatac cggttatacc ttctttcgta
    14041 aaatttctgc cgcacttgct ggcttcttgc caggcattat gctgacgcaa attggttatg
    14101 ttcccaacat cgcgcaaagc gatgcgacat tacagggttt gcgtcagctc atttttatct
    14161 ggccttgtgc actggcaatt attgctgcat tgacgatggg attcttttac acactcaatg
    14221 aaaaacggtt tgcattgatt attgaggaaa tcaaccaacg caaaaataaa gagatggcga
    14281 cagaagaaaa aacggcttcc gtaacgttat aaatgtcaat agccgctatt tccatcctgg
    14341 tgggtggcgg cctccctacg tttaaaaaat ggacttatta tgaaaaagat taatgcaata
    14401 attttattat cttctctgac ctctgcctcg gtatttgctg gcgcatacgt cgaaaacagg
    14461 gaggcatata atcttgcctc cgatcagggc gaggttatgc tacgtgtggg ttataacttc
    14521 gatatgggcg cgggtattat gttaaccaat acctacaact ttcagcgaga agatgaacta
    14581 aaacatggat ataacgaaat tgaaggctgg tatccgttat ttaaaccaac cgataaatta
    14641 accatccagc ccagtggctt aattaatgat aagagtatcg gttcgggtgg tgcagtgtat
    14701 ctggacgtca actataaatt tgtaccatgg tttaatctga cagtacgaaa tcgctataac
    14761 cataataact atagttcaac agatttgagc ggggaactgg ataataatga cacctatgaa
    14821 attggcacct actggaattt taaaatcacc gataaatttt cctatacatt tgagccacat
    14881 tacttcatgc gagtgaatga ctttaatagt agcaacggga aagatcatca ttgggaaatc
    14941 actaacacct tccgttaccg tattaatgaa cactggctcc cttatttcga attgcgctgg
    15001 ttagaccgca acgtcgaacc gtaccaccgc gagcaaaacc agatccgtat cgggacgaag
    15061 tatttcttct gatgtgaaac tgccggatgc ggcgtaaacg ccttatccgg cctacggttg
    15121 atacggtttt cgttggccgg attaagcaca tccggccatt aattaagctt cagccgccag
    15181 catctctttc ttacgttggc taatacgctt aaccagcatt acggaaacca ccgcaccact
    15241 gaatgcgaag caggccataa tgccaaacac gattttgtag ccaataatcc ccggatttaa
    15301 atccagaatg tagccataca gactgaagca gaacatcgcc ggagcgtaac caataaagct
    15361 acccaacgcc atcgccgcac ctgttttatt ttcagcaatt tttgcttcgc cgataggtgc
    15421 aaaaaatacg gctcgctgtg taaagactat cgcgccaaag cccagcgtac atgccatccc
    15481 taaatagacc ggcatacttt cgtgcggcag cataatcaac agtacgagcg cagcggtact
    15541 aatgataaag gtgtagcata gatatttact tggcgatttc aggatcttat ctgaaatcat
    15601 gccaccaatc ggtccaccaa tcattttcag acagtattgg ttaatgatgc cgtaagcccc
    15661 caccagcgca acgggcaata gatagatgtt tttcaggaat ggaatgaaga atgtcaggcc
    15721 acagtaaacc gcgtaaacga agaagacgtt aaaagcgata agccagatag ttttgtcttt
    15781 cagcaccgag gtcatactgg tgtttttcga tgctccgtct tcttttttca cctcaacgga
    15841 cggtgcctct tctttgtcat tcaggacaaa gaaaataata atgcctacgg caatcacaat
    15901 aagggaatag aaccagatgc ctgctttaaa acctaataag ccactgccaa accaggtaaa
    15961 tactgccaac gcagaaaatg ccaccacggt atcgacaatg ccacgccctg tttcgaagaa
    16021 gccaaacaac cgaccttgtt gttcgctatt gcccaatcga cttaccgact tgagcaagac
    16081 cggccagttc atcatgtcgc aagtaacgcc aaatagcgcc cagacaaaga ggatgcccca
    16141 ataccccggc attgtcgtca aataaacacc cagtaatcct gtcgcaatga gtgagaatga
    16201 catggtgtat ctgcgcggta gtttatcggc aaaataaata gacagaaaaa agcccactgt
    16261 ggtgacaaat gagtttaccg acatagcatt accaatttga ccattggtca aatggaaata
    16321 ttcctgcatc gggatataaa acgcatcttt cagcgacggt aatttataaa ttgtaccgcc
    16381 acacagtgtt aatagactaa ataacgccca tttctttttc gtgagcataa catcccctaa
    16441 gcgattttta aaatcactgt tttaaaggca ataagatacc gaccattcat atggaatggt
    16501 tttattaact gcgtatgagt taaaacttat tagtggttca gaagatggtt tgcctcttgt
    16561 ttgatttgtt gtagtacgtt acgcacatga tttatctgat taattgcatc ttctttttct
    16621 ttacgtaacc gcgcatccag taaatgattt tctggcaatg gtgtttcact catctggcga
    16681 taagggatcc acggattatc atcttcgtct tcaaagcgga acgccggcgc atagtaatca
    16741 acctcttctt ccaggccata tgccgtcacc tgcggctcat catcacccag gcagataagg
    16801 tgcgttaata acgctttgaa cggcatatca ccctgacctg aaatacaggc tttatgaccc
    16861 aggccacccg gttctttaac gatcaaggca tctttgatat ggacctgggt aatatgcggt
    16921 gccatcgttt ttaaagcgtc gatgggatgc tcatttgcat tgatcatgtt cgcaaaatca
    16981 aacagtaagg aaagagattc catctcactt tctttgacca gcgacaccag ctcatgactt
    17041 tttaaatctt catgctgctc gatcgtaaaa gtcaggccgc tgtcctgata cgtttcccgt
    17101 acataggcaa tgtcgttagc gataatcgat aatacgtcgc gcaaattacc ttcataacgt
    17161 ggataaaaac gtacggacga tgccccagtt ttcaacgcga tggcgacggc ttcgtcaata
    17221 gatgccttat ctgaggcgct ggtttcaata tgaatatcaa ggttcagacg gcgggcttta
    17281 tccccaaagg cagagagttc tttatcgtcc atattaccaa gagaaaaacg ctcgccatcg
    17341 agaacatgga ttttgacgcc acgtagatta ttttcacttg cgatatcaag taaatcagca
    17401 ggcaacactc tttccagccg catatttaaa tgaaaggcat aagcatgtaa ataaagagga
    17461 agagtgtcga cacgttgtag aatctttctt gcgttattta ttgtcaccat aaaacaccta
    17521 cagattaatg atgaggtcta cggcctcaaa tcgccaatat tcaatatcta tttggacaat
    17581 attgccttgc tggtcggcgc gatgcttttc aattaagatc gctggcatac ccgcagaacc
    17641 gccaagatac ttgctgatat cgcccggcat tctgacgggt ttgaaaatca atttttttac
    17701 taccgtctct ttttggtagc acttttccca gactgcagaa aatgagtggt tttcaagttg
    17761 ttcaataaag cccggagcaa cttcaggatt aatatatgtt tcgtgataga aaactttatg
    17821 tccttccagc gccccccagc cggtgatgcg atagagttca gttgatggcg tcactgcaat
    17881 cagtggcgcg agcgtctcgg gaatatcgct ggtacggttt ttctcggtaa acccccagga
    17941 aggctctcgc ccttgctcaa ttgcggcccg ctgaaagctc gccgacagct ccggactgta
    18001 attaaatcgc ggctgggtca cgaaccaccc cttacgatcc ttacggaaga ttttggattc
    18061 tgcctcgagg ttcaacaacg cctggcgcag cgtcatacgt ttaatgccca gcagttctcc
    18121 cagctctctt tctgaaggga gttttccacc cggcgtggtg atgccatctt tcaaccaccg
    18181 atccagtttc tcttttgcat tttctacggt ggattgattc tccgccattg tttaatcctt
    18241 ttggtttaaa ccagatgaag catcttacgc ttacgccaaa aaagaaagca attaacggcg
    18301 tatgactttg cagataattg tgacaaagct ctctattgac gtaaccacag acttataagg
    18361 gagatactcg cattggtgtg cgctcacgac aggcaaaaaa aaacctgcca tcgctggcag
    18421 gttttttatg actaaaaaac gaaattaatc gtctttcggt gcgcggttgg cgcggcgacg
    18481 atcgttttcc gtcaggtgac gtttacgaat acggatagag gtcggagtca cttctaccag
    18541 ttcgtcatca tcgatgaact ccagagcttg ttccagagtc atgcggatag gcggaaccag
    18601 aacaacggct tcgtcagtac cggaagcacg catgttggtc agtttcttac cggtcaggca
    18661 gtttacagtc aggtcgttag agcggctatg aataccgata atctgacctt cgtaaacttc
    18721 tgcaccgtga ccgaggaaca gcttaccgcg atcctgcaga ccgaacagcg cgaacgcgac
    18781 cgctttaccc tgaccgttag agatcagtac gccgttctga cgctgaccca cttcacccgg
    18841 acgtacgtcg tcgtagtggc tgaaggtgga gtacagcaga ccagtaccgg aagtcatggt
    18901 catgaactca gaacggaagc caatcagacc acggcttggg atcacgtagt cgagacgtac
    18961 gcggccttta ccgtctggat tcatgttttt caggtcgcct ttacgttcgc ccagcgcctg
    19021 cattacagaa ccctgatgct gttcttcaac gtccagagtc acgttttcat acggctcttg
    19081 tttacgaccg tcgatttcac ggaagataac tttcggacgg gataccgcca gttcgaaacc
    19141 ttcacgacgc atgttttcga tcagaacaga caggtgcagt tcgccacgac cagaaacgcg
    19201 gaacgcatcg gcgtcttcgg tttcttctac gcgcagcgca acgttgtgta ccagttcttt
    19261 gttcagacga tccaggatct gacgagacgt tacgaactta ccttctttac cgcagaacgg
    19321 cgaggtgtta acgcagaaga acatagaaac ggtcggctca tcaacggaga gtgccggcag
    19381 cgcttcaacg ttttgcgtgt cgcaaacggt gtcagaaatg ttcagttcgc caaggcccgt
    19441 gatcgcaacg atatcgccag cttccgccag atcggtttcg atacgttcca gaccgaggtg
    19501 gcccagcact ttaccgactt tcgcgttgcg ggttttgcct tcgctatcga tgatagtgac
    19561 ctgctggttc ggcttcactt taccgcgctt gatgcggcca atgccgataa cgccaacata
    19621 gctgttgtaa tcgagctgag aaatctgcat ctggaacgga ccgtcaaggt caacgtccgg
    19681 cgcaggaacg tggtcaacaa tcgcctggta cagcggggtc atgtcttccg ccatatcttc
    19741 gtggtccaga cccgcgatac cgttcagcgc agaagcgtaa acgatcggga agtccagctg
    19801 ctcgtcggtc gcgtcgaggt taacgaacag atcgaatacc tgatccacaa cccaatcagg
    19861 acgcgcgcca gggcggtcaa ctttgttgat aacaacaatc ggcttcaggc cgtaagcaaa
    19921 cgcttttttg gttacgaagc gcgtttgcgg catcgggccg tcaaatgcgt caaccaccag
    19981 cagcactgag tctaccatgg acattacacg ttcaacttca ccaccgaagt cggcgtgccc
    20041 cggggtatca acgatgttga tacggtaatc attccatttg atagcggtgt ttttcgcgag
    20101 gatggtaatc ccacgctctt tctccaaatc gttggagtcc atcacgcgct cttgggtttc
    20161 ggcacgagag tcgaacgtac cggattgttg gagcagcttg tctaccaggg tggttttacc
    20221 atggtctacg tgcgcgatga tggcgatatt acgcaatttt tcgatcacaa ctttgcctca
    20281 ggcattagaa atagcgcgtt attgtacacg gattaatcgc actacaaaac aggatcacaa
    20341 acatcctccg caaacaagta ttgcagagtc cctttgtgat cgctttcacg gagcataaaa
    20401 agggttatcc aaaggtcatt gcaccaacat ggtgcttaat gtttccattg aagcactata
    20461 ttggtgcaac attcacatcg tggtgcagcc cttttgcacg atggtgcgca tgataacgcc
    20521 ttttaggggc aatttaaaag ttggcacaga tttcgcttta tcttttttac ggcgacacgg
    20581 ccaaaataat tgcagatttc gttaccacga cgaccatgac caatccagga gagttaaagt
    20641 atgtccgctg aacacgtact gacgatgctg aacgagcacg aagtgaagtt tgttgatttg
    20701 cgcttcaccg atactaaagg taaagaacag cacgtcacta tccctgctca tcaggtgaat
    20761 gctgaattct tcgaagaagg caaaatgttt gacggctcct cgattggcgg ctggaaaggc
    20821 attaacgagt ccgacatggt gctgatgcca gacgcatcca ccgcagtgat tgacccgttc
    20881 ttcgccgact ccaccctgat tatccgttgc gacatccttg aacctggcac cctgcaaggc
    20941 tatgaccgtg acccgcgctc cattgcgaag cgcgccgaag attacctgcg ttccactggc
    21001 attgccgaca ccgtactgtt cgggccagaa cctgaattct tcctgttcga tgacatccgt
    21061 ttcggatcat ctatctccgg ttcccacgtt gctatcgacg atatcgaagg cgcatggaac
    21121 tcctccaccc aatacgaagg tggtaacaaa ggtcaccgtc cggcagtgaa aggcggttac
    21181 ttcccggttc caccggtaga ctcggctcag gatattcgtt ctgaaatgtg tctggtgatg
    21241 gaacagatgg gtctggtggt tgaagcccat caccacgaag tagcgactgc tggtcagaac
    21301 gaagtggcta cccgcttcaa taccatgacc aaaaaagctg acgaaattca gatctacaaa
    21361 tatgttgtgc acaacgtagc gcaccgcttc ggtaaaaccg cgacctttat gccaaaaccg
    21421 atgttcggtg ataacggctc cggtatgcac tgccacatgt ctctgtctaa aaacggcgtt
    21481 aacctgttcg caggcgacaa atacgcaggt ctgtctgagc aggcgctgta ctacattggc
    21541 ggcgtaatca aacacgctaa agcgattaac gccctggcaa acccgaccac caactcttat
    21601 aagcgtctgg tcccgggcta tgaagcaccg gtaatgctgg cttactctgc gcgtaaccgt
    21661 tctgcgtcta tccgtattcc ggtggtttct tctccgaaag cacgtcgtat cgaagtacgt
    21721 ttcccggatc cggcagctaa cccgtacctg tgctttgctg ccctgctgat ggccggtctt
    21781 gatggtatca agaacaagat ccatccgggc gaagccatgg acaaaaacct gtatgacctg
    21841 ccgccagaag aagcgaaaga gatcccacag gttgcaggct ctctggaaga agcactgaac
    21901 gaactggatc tggaccgcga gttcctgaaa gccggtggcg tgttcactga cgaagcaatt
    21961 gatgcgtaca tcgctctgcg tcgcgaagaa gatgaccgcg tgcgtatgac tccgcatccg
    22021 gtagagtttg agctgtacta cagcgtctaa gtgttttagt tgccgtggaa acttttcgcc
    22081 tgtctctggc aggcctggga tcggtggcaa gcacatcacg ccggatgcga cgcaaatgcg
    22141 tcttatccgg cctacacggt gatgatgtgg taggccggag caggtgagtc gctctccaac
    22201 gtgaagtttg tcagctatct gtagcccatc tctgcatggg cttttttctc cgtcaattct
    22261 ctgatgcttc gcgcttttta tccgtaaaaa gctataatgc actaaaatgg tgcaacctgt
    22321 tcaggagact gctttatggc aacaggcacg cagcccgatg ctgggcagat cctcaactcg
    22381 ctgattaaca gtattttgtt aatcgatgac aacctggcga tccattacgc caaccctgcc
    22441 gcgcaacaac tgctcgccca aagctcccgc aaattgtttg gtacaccgtt accggaactg
    22501 ttgagctact tctcattaaa tatcgagctg atgcaagaaa gtctggaggc ggggcaaggt
    22561 tttaccgata acgaagtgac gctggtcatc gacgggcgct cgcatatcct ttctgtgacg
    22621 gcccagcgta tgccggacgg catgatcctg ctggagatgg ctccgatgga taaccagcgc
    22681 cgcttaagtc aggaacagct acagcacgcc cagcaggttg ctgcccgtga tttagtgcgc
    22741 ggcctggcac atgagattaa aaatccgctt ggcggtttac gtggcgcggc gcagctgctc
    22801 agcaaagcgt tacctgaccc atcactactc gaatatacca aagtgattat cgaacaggcg
    22861 gaccggctgc gaaatctggt cgaccgtctg ttggggccgc agctgcccgg tacgcgcgtt
    22921 accgaaagta ttcacaaagt ggctgaacgc gtggtaacgc tggtgtcgat ggaactgccg
    22981 gacaacgtgc ggttgattcg tgattacgat cccagcctac cggaactggc gcacgacccg
    23041 gatcaaattg aacaggtctt gctgaatatt gtgcgcaatg cgctacaggc gctggggccg
    23101 gaaggcggtg aaatcattct gcgtacccgc accgcgtttc aactgacctt acacggcgag
    23161 cgctaccggc tggcggcgcg gattgatgtg gaagataacg ggccgggcat tccgcctcat
    23221 ttgcaggata cgctgtttta cccgatggtc agcggccgcg aaggtggcac cgggcttggc
    23281 ttatccatcg ctcgtaattt gattgatcag cattcaggca aaattgaatt taccagttgg
    23341 ccagggcata ccgagttctc ggtttacctg cctatcagga aataaaggtg acgtttatgc
    23401 aacgagggat agtctgggta gtcgatgacg atagttccat ccgttgggtg cttgaacgtg
    23461 cgctcgctgg ggcaggttta acctgtacga cgtttgagaa cggcgcagaa gtgctggagg
    23521 cgctggcgag caaaacgccg gatgtgctgc tttcagatat ccgtatgccg ggaatggacg
    23581 ggctggcgct gctcaagcag attaaacagc gccatccaat gcttccggtc atcattatga
    23641 ccgcacattc cgatctggat gctgccgtca gcgcctatca acaaggggcg tttgattatc
    23701 tgcccaaacc gtttgatatc gacgaagcag tggcgctggt tgagcgcgct atcagtcatt
    23761 accaggaaca gcagcagccg cgtaatgttc agcttaacgg cccaacgacc gatatcatcg
    23821 gcgaagcgcc agccatgcag gacgtgttcc gtattatcgg tcggctttcg cgttcttcta
    23881 ttagcgtgct gattaacggc gaatccggca ccggtaaaga actggtcgct catgccctgc
    23941 atcgccacag tccgcgcgcc aaagcgccgt ttatcgcgct gaatatggca gctatcccaa
    24001 aagatttgat cgaatcagaa ctgtttggcc acgagaaagg cgcgtttact ggcgcgaata
    24061 ccattcgtca ggggcgtttt gaacaggccg atggcggtac attattcctc gacgaaattg
    24121 gtgatatgcc gctggatgtg cagacgcgtt tgctgcgcgt gctggcagac ggtcagtttt
    24181 accgcgttgg cggctatgcg ccggtgaaag tggatgtgcg gattatcgct gccactcacc
    24241 agaatctcga acagcgagtg caggaaggta agttccgtga ggatctgttc caccgcctga
    24301 acgttatccg cgttcatctg ccgccgctgc gcgaacgtcg ggaagatatt ccccgtctgg
    24361 cgcgccattt tttacaggtt gccgcgcgcg aactgggcgt agaagcgaag ttactgcatc
    24421 cggaaaccga agctgctctg acgcgtctgg cgtggccagg caacgtgcgc cagctggaaa
    24481 acacctgccg ctggctaacg gtgatggccg ccgggcagga agtgttgatt caggatttgc
    24541 ccggcgaact gtttgaatca acggttgcgg agagtacttc gcaaatgcaa ccggacagct
    24601 gggcgacgct tcttgcgcag tgggcagaca gagcgctgcg ttccggtcat caaaatctgc
    24661 tttccgaagc gcagccagag ctggagcgga cgttactgac gaccgcgttg cgacatacgc
    24721 aggggcataa acaggaagcg gcgcggctac tcggctgggg ccgcaacacc ctgacgcgta
    24781 agttaaaaga gctggggatg gagtgattca cagcttgtgt gtaaagattg attattgagc
    24841 gcaaattgct ggtattttac gctttactgt tccgataagt tcagtatgat cttgcccgga
    24901 aaacggggag agtcattatg ctggaatcaa taattaatct ggtatcgagt ggcgcagttg
    24961 acagccacac accgcaaact gccgttgctg ccgtgctgtg tgccgcaatg attgggctgt
    25021 ttagctgaag ctcgttgttt atgccggatg cggagaaagt cgtaggcctg ataagacgcg
    25081 accagcgccg catcaggcat catgctcaga tgcctgatgc ggcgtaaacg ccttatccgg
    25141 cctacaaaag caataatttc aacaggtttt gttgcccagc gcatcaggca atcttgttct
    25201 cagcacattg atggcgcttt cgttttctac tttgtaaacg aagcgccatt cactatttaa
    25261 atcacccgag agaactgctg catccgcgct ttctggcgca gataggtatc aaagcacatg
    25321 caaatgttgc ggatcagcaa gcgacctttc gccgtcacct gtattccctt ctcatccaca
    25381 tccaccagcc catcttttgc taacggggcg agcagcttga gatcttccgc aaagtaatca
    25441 gcgaagtgca aatcccactg tttctcaata ggggcgtaat ccagacggaa gttgcagatg
    25501 agcgacttaa tcacatcgcg gcgaatacag tcatcacgcg ttagcgcaat accacgccac
    25561 agcgcattgc cttgttcatc cacttgctga tagtactgct tcaactcttt ctggttctgc
    25621 gcgtagcagt cgccaatcat gctgatggcg gaaacgccca tccccagcag atcggtatcg
    25681 ccctgagtgg tgtagccctg gaagttacga tgcagcacgc cttcacgctg ggccaccgcc
    25741 agctcgtcat ccggacgggc aaagtgatcc ataccgataa actgatagcc cgattgcgtc
    25801 aggaaggcga tggtttcctg caggatatcg agtttttgct gcggactcgg caggtcagca
    25861 tctttgattt tgcgctgagc agcaaaaatg gtcggcagat gcgcgtagtt aaagacactc
    25921 agacgatcgg ggttcagctc cgccacacgt ttcagggtaa aggcgaaact ctccggcgtc
    25981 tgtttcggca ggccgtaaat caggtcgatg ttggtggagg taaaaccaat ctcacgcgca
    26041 tggttaagca gtgcaaagat gaactcttca tcctgctcgc ggttaaccag acgttgcact
    26101 tctttgttga agtcctgcac gcccatgctc aggcgattaa agccttcggc gcgtaaatga
    26161 tcgagtacat ccagttcgat ttcccgcgga tcgacttcga tcgaaatctc cgcatcggca
    26221 ttgaactgga agttttcgcg cagcagcttc atcaggcggc tgatttgcgc tttattcaga
    26281 tacgtcggcg ttccgccgcc ccagtgcaat tggctgacgt gacgcccggc gaacagcggt
    26341 gcacgatgga cgatttcttg ctccagcgcg tccagatact gatcggcctt gtgctgctgg
    26401 cgagtaacaa tcttattgca accgcagaag taacaaagct tatggcagaa cgggatatgt
    26461 acgtagagag ataatggacg ctcaggatag cgcgccacgg cttgtaaaaa cgcctgttcg
    26521 ccgaagtctt ctgaaaactc cagcgcggtc gggtacgagg tgtatcgtgg cccggaatag
    26581 ttatatttct ggatcagggc cagatcccag tcgatttgct gtacagacat gctcactcct
    26641 tccgatggcg tctctggcgg ctacggcgta ccggcggatg cccgtttcgg gtcatcagcc
    26701 ggttgcgcag ccacttttgt cgccgcgaca accgctgtag tttaacgaat aaccacacca
    26761 gataacatat aaccggaagg gttatcagca gaacgggaag gcccacggcg gcaatccgtt
    26821 agttgccccg cagcagacgc atcatgtctt cttgcttctc gtcttcttcc tcttcttcgt
    26881 catcgtcata agagaggccg agtttctgca tcaactcatc aatacgatcc agtttagcat
    26941 ccacccagga ttgctcttcg gcactcaggg tttcgcctgc ttccagacgt tccagcagcg
    27001 catccagacg ctcatccgtt tccagtaatt ccaactccgc ctgcggtgaa agcataggtt
    27061 tctcactctt cggtttgtgc tgtttggtga ctttttcagt cacgcccaat ggaatagggg
    27121 ttttactgcc aatacgtgga tcttttggtg cgttctggcc tttgctgcct gacgtggtgt
    27181 ttccgcccgc tgcgcggctg cccggcgcat gaccacgacg ttttttctga cgcttgcgat
    27241 cacgagcttc ctgatccagc tcctcgcgtg tttttcgacg cgcttttgca tgacctttgc
    27301 tgcgtgagtt tgaagatgat ggtttcataa tggttcgtct tttagccgtt ttattcagta
    27361 tagatttgcg gcggaatcta acagaaagca agcaaagaaa aaaggcgaca gattactctg
    27421 tcgccttttt tcctgactca taacccttaa cgggtcttac aatccttgca ggccgccaac
    27481 acaccctgtt tttcctttag ccggaacaat ccgtgttgat tccatttccg tttaattacg
    27541 tctccggacg tttgtcttcc tgacaatcct ctgtcttcgc ctcctggcgc tcctgaccct
    27601 catcctgagt cattgttcct gttagcgtcc tcgctctatg ggtgctactt tacgcctttg
    27661 ctttaaacaa acaatcaacc gccatcagta tttgcacatt ttcagagttt tatataaaag
    27721 caattcactg atttatatag cttatttgac atgcatcgca gaattttctc tgctatttcg
    27781 cataaagact atcggcaatg tctcacaaag cgtatggctt ttacttacaa cgctcacgcc
    27841 gaaaaatccg ccttttatta tggttcaggt ataatcgcca caaagctttg actgacggag
    27901 acgaccgctt tgactaattt gaattatcaa cagacgcatt ttgtgatgag tgcgcctgat
    27961 attcgccacc taccttccga taccggaatt gaagtggctt ttgcaggccg ttccaacgca
    28021 ggtaaatcca gcgcgctgaa cacgctgact aaccagaaaa gcctggctcg tacctcaaaa
    28081 accccagggc gcacccagct tatcaacctg tttgaagtgg ctgacggcaa gcgtctggtt
    28141 gacttgcctg ggtacggtta tgcggaagtc ccggaagaga tgaagcgcaa atggcagcgt
    28201 gcgctcggcg aatacctcga aaaacgtcag agcctgcaag gtctggtggt gctaatggat
    28261 attcgccatc cgctgaaaga tttggatcag cagatgattg agtgggcggt agacagcaat
    28321 atcgccgttc tggtgctgct gaccaaagcg gacaaactgg caagcggcgc acgtaaagcg
    28381 caattgaata tggtgcgtga agctgtactg gcgtttaacg gtgatgtgca ggttgaaacg
    28441 ttttcttcgt tgaagaaaca aggcgtggac aagctgcggc agaaactgga tacctggttt
    28501 agcgagatgc agcctgtaga agaaacgcag gacggcgaat aattttcttg ccttaatgct
    28561 tgtgccggat gtggcgtatc cggcccgtaa attcaataga ttacaattct accgttggcc
    28621 tgataaacat agcgcatcag gcattacgga tcttttcttt cgcccaataa aaaacgcccc
    28681 agtcattact gactggggcg gctaaaatat tcagccaaat ccgattacgt gaagtaaaag
    28741 gtctgaaaga tagaacatct tacctctgta ccctacgcga ctaactttac tcttttttgt
    28801 tcagttcaga aagcactttt tgtaattttt tttcagttgt tgcataggaa tttctaatag
    28861 ccatcacaaa acgtgacagc ttatgttgct tacttacgaa aaaaggcatg ttcaggcgaa
    28921 tcttagtgcg cctgatccca gttttcgcca ctccccactt ccaccagcaa cggcacatcc
    28981 agacgggtac agttttccat cagttgatga atctgcttcg cgacggcatc aacatcatct
    29041 ttatgaactt caaataccag ttcatcgtgt acctgcatga tcatacgtac acgcggttgc
    29101 tcagcctgta accacgcatc aacggcaatc atcgcccgtt tgataatgtc ggcggcggtt
    29161 ccctgcattg gcgcgttaat ggctgcacgt tcagccgctg cacgacgagc accattgctg
    29221 gatttgatat ccggcagata cagacggcgt ccgtccagcg tttcaacgta gccctgctct
    29281 ttcgcctgag cacgggtgcg ttccatatac tccagcacgc cagggtagcg ttcgaagtaa
    29341 aggtccatgt acttctgcgc ttctttacgt ggaatgttca attgccgcgc cagaccgaaa
    29401 gcactcatgc cataaatcag accaaagttg atcgctttcg cgctacggcg ttgctcgctg
    29461 gtgacggttt ccagtggcaa accaaacact tctgccgccg ttgcccggtg gatatctttt
    29521 ccttccgcga atgcggtcag caagcctttg tcacgcgaaa gatgcgccat aatgcgcagt
    29581 tcaatctgcg agtagtccgc tgagacaatc acataatcct ctggcgcaat aaacgcctgg
    29641 cggatacgac gaccttcttc gttacgcacc ggaatgtttt gcaggttagg atcggttgac
    29701 gataaacgtc ccgttgcagt tactgcctgg tgataagagg tatgcacacg cccggttttc
    29761 gggttgatca tcagcggcag cttgtcggtg taggtcgatt tcagcttcgc cagaccacga
    29821 tactccagaa tcacttttgg caacggatag tccagcgcca gttcttccag tacctcttcc
    29881 gacgttgacg gcgcgccacc cggcgttttc ttcagcggtt taatgccctg tttttcaaag
    29941 agaatggttt gtaactgctt ggtggaagaa aggttaaatt cctcacctgc aatttcatgc
    30001 gctttctttt ccagctcagc cagacgaagg gtgagctctt cagaatgatt gtgcagcact
    30061 ttcggatcga tcttcacacc gttacgttca atgcgtgaaa gcaccggcac cagcggcatt
    30121 tcgatattct cgaagacgtt caacggccct ttgtgttttt gcagatccgg ccacattttc
    30181 agatgcaact gcaaggtgac atctgcatct tcggcggcgt aacgtccggc ttcttcgagg
    30241 gcaatctggt taaaggtcag ttgatttttg cctttaccag caatctcttc aaaagtgatg
    30301 gttttgtgct tcaaccaacg ttccgcgagg ctgtccatat cgtgacgccc ggcaacgcta
    30361 ttgagaatgt aggactccag catggtatca aacgcaatcc cacgcagttc aatgccgtag
    30421 ttcgccagaa taccgcgatc gtatttcagg ttttgcccga ccttcagcgc cttttcatct
    30481 tccagcagcg gttttagcaa ctcgagtgca cgctcgcgag agatttgatc gggcgcatca
    30541 agataatcat gagcaaccgg aatatatgcc gctacgcctg gctcgatagc aaaagaaagc
    30601 ccgaccaggt tagcagagat gttatcaagg ctgtcggttt cggtatcaaa tgcaaatacc
    30661 ggcgcttttt ccagcttcgc aatccacgct ttcagtgttt cttcatcaag gatggtgacg
    30721 tagttgtcat aagaaatcac cgttgccgtc acttctggtg cttcgtctgc aacactggtt
    30781 tcctgtggct tcgcggctgg ttttgcccct ttggcctgta accatttgcc cgcttcgaca
    30841 tcagcagtcc agcgtttgaa ctcatacttt ttgaacagcc ccaacaactc ttccgctgcc
    30901 ggttgctgca cttccagttg ttcacaggtc agctccagtt caacgtcggt tttaatcgtc
    30961 gccagctggt atgagagata agcaacttct ttgttttgct cgagcttcgc tgccattgtt
    31021 ttcgcgccac ggaagctcaa cccagcaatt ttttctggct cggcatacag cgtatccagt
    31081 ccgccaagac cttgcagcaa tgcctgcgcg gttttttcac cgacgcccgg tacgccagga
    31141 atgttatcag aggagtcacc catcagcgcc aggaaatcga tgatcagttc tggcggcacg
    31201 ccgtacttat tcaccacctc ttccggtccg aggatggtat tcgtcatggt attgataagc
    31261 gtaatatttg gcgtcaccag ctgcgccata tctttatcgc cagtgctgat cagcaccgga
    31321 cgcccggctt tttcggcttc gcgcgccaga gtaccgataa cgtcgtccgc ttctacgcca
    31381 gaaaccgcca gcagcggcag tcccatcgct ttaaccatcg cgtgcaaggg ttcgatttgt
    31441 gcacgcagat cgtccggcat tggcgggcga tgtgatttgt aatgttcaaa cagttcatca
    31501 cgaaaggttt ttcccttggc gtcaaagacc accgctgcat gcgtcggttt atattgcatg
    31561 atcagactgc gcagcatgtt gaggacacca tacatcgcac cggtcggctc gcctgcgctg
    31621 ttagtcagcg ggggaaacgc gtgatatgcg cgataaagat aagatgaacc atctacaagg
    31681 ataagtggat tttgggggat ctgaaccata atgtccgtgc ctgtttatca gattatgggt
    31741 aaaggatgcc acagacagga tgaaaacatg agtttttcac cgcttttcgt gaaaatcttt
    31801 tgtagatctt ctggatcgct cgcaaatcgt catgtggata actttgtgca taaattattt
    31861 acatcgcttt taatttatta tcatgctttt tacagcatga tgtttgtctt tgtttttcat
    31921 gcagttaaaa ataaatccat ccctaataat tgagataatg ggattttttc taatgtggat
    31981 agatatgaat tatttttctc cttaaggatc atccgttatt tgggtcgttt tctgctaaaa
    32041 tctgcgcctt gcgcttcttt agcgcactgt ctatggctaa ccttttgaat aaattcatta
    32101 tgacgagaat actcgctgcg ataacccttt tgctgagtat cgtattgacc attttggtca
    32161 ctattttttg ttccgtcccg atcatcattg ccgggattgt aaaactattg ctacctgtgc
    32221 cagtcatttg gcgaaaggtt tcgcgttttt gtgattttat gatgtattgc tggtgtgaag
    32281 gtctggcggt attactgcat ctgaacccac accttcaatg ggaagttcac gggctggaag
    32341 ggttaagtaa gaagaactgg tatctgctta tttgtaacca ccgtagttgg gcagatattg
    32401 tcgtactgtg cgtgctgttt cgtaagcaca ttccgatgaa taaatatttc ctcaagcaac
    32461 agctggcctg ggtgccattt cttggcctgg cgtgctggtc gctggatatg ccgtttatga
    32521 agcgttattc ccgcgcttat ttattacgtc atccggagcg acgtggtaaa gatgttgaaa
    32581 ccactcggcg ttcttgtgaa aagtttcgcc tgcatcccac caccattgtc aatttcgttg
    32641 aaggctcccg tttcacgcaa gaaaaacatc agcaaaccca ctccactttt caaaacttgt
    32701 tgccaccaaa ggcggcaggc attgcgatgg cgctaaatgt actgggtaaa caattcgata
    32761 aactgcttaa tgttacgctg tgttatccgg acaataaccg tcagccgttc ttcgatatgt
    32821 taagcggtaa actgacgcgg attgtcgtac atgtggattt acagcctatt gccgatgagt
    32881 tacatggcga ctacatcaat gacaaaagct ttaagcgcca ttttcagcaa tggctgaact
    32941 cattgtggca ggaaaaagac cggcttctga cgtctctcat gtcatcacag cgtcagaata
    33001 agtaagtttt actcgcctct gaatgagcag aggcgagtga gtattttaat gaacaaaacg
    33061 tccggcacga gacataaatt cttcttcgct catctcctgt ccgttaaaaa caactttacc
    33121 cggtgtataa cgcagctgca gcgaggcggt attgttgtca atcgtgatta actgaaacat
    33181 ctgacctaat gtcatcatcc cgctgatttg tttatcagcc tgcttttgcg ctttttccgc
    33241 atccattcct tcagataaat taagctgttt tgcggtttct gtgacgacat taagcggtaa
    33301 cttcacatca aaattgagcg atttgatatc tttgtttgtg gatgatgaag atttggctgg
    33361 gtcggcaata ctgatatcca gattggcatt tagttcgccg agtgcgttct tccatcttac
    33421 cggttgttta atggtcggct cacttttttg taataacggt aaatactctt tgaacaatgc
    33481 agcattcact tcttgcagag caacttcatc gtttgctaac tcagggtgtg cagcaagctg
    33541 cttctgcatc gcaatgttat actggatgat aaattggcgc actgctgagg gatcaataga
    33601 ttcagcaatc aatgaccact caccactacc gagttgctga ttcccttttg ttaacttatc
    33661 aagttcgtag gtgagattga cattgatata atctttgtct ttaacgcgat ccagcctggt
    33721 ttttgcaacg aaagcatcga tttgggcaac gtcttccccg tgattgataa tgttaatctg
    33781 attaaatttc gactcgcttt caccaaccgg aaatttcttt tcttctaatc gcgccagaga
    33841 atcaatggta aaactttttg ccgttacttt gttcattggt gataattgca gaacaatatc
    33901 ttcgactttg ccttcaatat ccaggttaga caatgaacta ccatcaccat taaaagtaaa
    33961 ctggccctca ccaaaagaaa actttccata ctctgcaggg gcaacatcta atgtcgtaga
    34021 gaatgagcca ccaaacgcga atcgcaatgt cgcttccacg ggcgatttat ttttcgcggc
    34081 gataaatagc ggttgtgtca gttcattatt cactaagttc acttttgccg ctgccagtgc
    34141 tgggatgaca ttaccatgca ttaacattgt gatgggcaac ggaccgtgct caacatccac
    34201 atcaaataca actttctggc ctggcttgat attgagatcg ggtgcaccgt tatcgaatgt
    34261 catttgcatt tgaaaacggg aattaaaaaa gcctttgtca aaattttgat aacttaacgt
    34321 catatcgtag gcatgttcac ctttcttttt agcatcgtta aaatctttaa taaatttttc
    34381 gacaccaggc tgaatttgcg tacctgtgta ccatgtgcca ccaccccaga ttacggctaa
    34441 cgcaacaata acacctgtag ctgacttacg tatcatataa atattccctg ataaaacagc
    34501 aaaactttga atatccactt atgctga
//
LOCUS       DAPOAV010000047        33617 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.047, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000047 DAPOAV010000000
VERSION     DAPOAV010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33617
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.047"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            10..1929
                     /gene="ygfT"
                     /locus_tag="RN951_002515"
     CDS             10..1929
                     /gene="ygfT"
                     /locus_tag="RN951_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417363.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent uric acid utilization protein
                     YgfT"
                     /protein_id="HDX2527498.1"
                     /translation="MNKFIAAEAAECIGCHACEIACAVAHNQENWPLSHSDFRPRIHV
                     VGKGQAANPVACHHCNNAPCVTACPVNALTFQSDSVQLDEQKCIGCKRCAIACPFGVV
                     EMVDTIAQKCDLCNQRSSGTQACIEVCPTQALRLMDDKGLQQIKVARQRKTAAGKASS
                     DAQPSRSAALLPVNSRKGADKISASERKTHFGEIYCGLDPQQATYESDRCVYCAEKAN
                     CNWHCPLHNAIPDYIRLVQEGKIIEAAELCHQTSSLPEICGRVCPQDRLCEGACTLKD
                     HSGAVSIGNLERYITDTALAMGWRPDVSKVVPRSEKVAVIGAGPAGLGCADILARAGV
                     QVDVFDRHPEIGGMLTFGIPPFKLDKTVLSQRREIFTAMGIDFHLNCEIGRDITFSDL
                     TSEYDAVFIGVGTYGMMRADLPHEDAPGVIQALPFLTAHTRQLMGLPESEEYPLTDVE
                     GKRVVVLGGGDTTMDCLRTSIRLNAASVTCAYRRDEVSMPGSRKEVVNAREEGVEFQF
                     NVQPQYIACDEDGRLTAVGLIRTAMGEPGPDGRRRPRPVAGSEFELPADVLIMAFGFQ
                     AHAMPWLQGSGIKLDKWGLIQTGDVGYLPTQTHLKKVFAGGDAVHGADLVVTAMAAGR
                     QAARDMLTLFDTKAS"
     gene            1929..2417
                     /locus_tag="RN951_002516"
     CDS             1929..2417
                     /locus_tag="RN951_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417362.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDX2527499.1"
                     /translation="MKSLIIVNPADCIGCRTCEVACVVAHPSEQELNADVFLPRLKVQ
                     RLDSISAPVMCHQCENAPCVGACPVGALTMGEQVVQTNSARCIGCQSCVSACPFGMIT
                     IQSLPGDTRQQIVKCDLCEQREEGPACVESCPTQALQLLTERELRRVRQQRIVASGEN
                     PL"
     gene            complement(2453..3820)
                     /gene="ghxQ"
                     /locus_tag="RN951_002517"
                     /gene_synonym="ygfQ"
     CDS             complement(2453..3820)
                     /gene="ghxQ"
                     /locus_tag="RN951_002517"
                     /gene_synonym="ygfQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine/hypoxanthine transporter GhxQ"
                     /protein_id="HDX2527500.1"
                     /translation="MSGDILQTPDAPKPQGALDNYFKITARGSTVRQEVLAGLTTFLA
                     MVYSVIVVPGMLGKAGFPPAAVFVATCLVAGFGSLLMGLWANLPMAIGCAISLTAFTA
                     FSLVLGQQISVPVALGAVFLMGVIFTAISVTGVRTWILRNLPMGIAHGTGIGIGLFLL
                     LIAANGVGMVIKNPIEGLPVALGAFTSFPVMMSLLGLAVIFGLEKCRVPGGILLVIIA
                     ISIIGLIFDPAVKYHGLVAMPSLTGEDGKSLIFSLDIMGALQPTVLPSVLALVMTAVF
                     DATGTIRAVAGQANLLDKDNQIINGGKALTSDSVSSIFSGLVGAAPAAVYIESAAGTA
                     AGGKTGLTATVVGALFLLILFLSPLSFLIPGYATAPALMYVGLLMLSNVSKLDFNDFI
                     DAMAGLVCAVFIVLTCNIVTGIMLGFVTLVVGRVFAREWQKLNIGTVIITAALVAFYA
                     GGWAI"
     gene            complement(3856..5172)
                     /gene="guaD"
                     /locus_tag="RN951_002518"
     CDS             complement(3856..5172)
                     /gene="guaD"
                     /locus_tag="RN951_002518"
                     /EC_number="3.5.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311783.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine deaminase"
                     /protein_id="HDX2527501.1"
                     /translation="MSGEHTLKAVRGSFIDVTRTIDNPEEIASALRFIEDGLLLIKQG
                     KVEWFGEWENGKHQIPDTIRVRDYRGKLIVPGFVDTHIHYPQSEMVGAYGEQLLEWLN
                     KHTFPTERRYEDLEYAREMSAFFIKQLLRNGTTTALVFGTVHPQSVDALFEAASHINM
                     RMIAGKVMMDRNAPDYLLDTAESSYHQSKELIERWHKNGRLLYAITPRFAPTSSPEQM
                     AMAQRLKEEYPDTWVHTHLCENKDEIAWVKSLYPDHDGYLDVYHQYGLTGKNCVFAHC
                     VHLEEKEWDRLSETKSSIAFCPTSNLYLGSGLFNLKKAWQKKVKVGMGTDIGAGTTFN
                     MLQTLNEAYKVLQLQGYRLSAYEAFYLATLGGAKSLGLDDLIGNFLPGKEADFVVMEP
                     TATPLQQLRYDNSVSLVDKLFVMMTLGDDRSIYRTYVDGRLVYERN"
     gene            complement(5190..6590)
                     /gene="xanQ"
                     /locus_tag="RN951_002519"
     CDS             complement(5190..6590)
                     /gene="xanQ"
                     /locus_tag="RN951_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417358.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/proton symporter XanQ"
                     /protein_id="HDX2527502.1"
                     /translation="MSDINHAGSDLIFELEDRPPFHQALVGAITHLLAIFVPMVTPAL
                     IVGAALQLSAETTAYLVSMAMIASGIGTWLQVNRYGIVGSGLLSIQSVNFSFVTVMIA
                     LGSSMKSDGFHEELIMSSLLGVSFVGAFLVVGSSFILPYLRRVITPTVSGIVVLMIGL
                     SLIKVGIIDFGGGFAAKSSGTFGNYEHLGVGLLVLIVVIGFNCCRSPLLRMGGIAIGL
                     CVGYIASLCLGMVDFSSMRNLPLITIPHPFKYGFSFSFHQFLVVGTIYLLSVLEAVGD
                     ITATAMVSRRPIQGEEYQSRLKGGVLADGLVSVIASAVGSLPLTTFAQNNGVIQMTGV
                     ASRYVGRTIAVMLVILGLFPMIGGFFTTIPSAVLGGAMTLMFSMIAIAGIRIIITNGL
                     KRRETLIVATSLGLGLGVSYDPEIFKILPASIYVLVENPICAGGLTAILLNIILPGGY
                     RQENVLPGITSAEEMD"
     gene            complement(6755..9625)
                     /locus_tag="RN951_002520"
     CDS             complement(6755..9625)
                     /locus_tag="RN951_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase
                     Mo/Fe-S-binding subunit"
                     /protein_id="HDX2527503.1"
                     /translation="MIIHFTLNGAPQELTVNPGENVQKLLFNMGMHSVRNSDDGFGFA
                     GSDAIIFNGNIVNASLLIAAQLEKADIRTAESLGKWNELSLVQQAMVDVGVVQSGYND
                     PAAALIITDLLDRIAAPTREEIDDALSGLFSRDAGWQQYYQVIELAVARKNNPQATID
                     IAPTFRDDLEVIGKHYPKTDAAKMVQAKPCYVEDRVTADACVIKMLRSPHAHALITHL
                     DVSKAEALPGVVHVITHLNCPDIYYTPGGQSAPEPSPLDRRMFGKKMRHVGDRVAAVV
                     AESEEIGLEALKLIDVEYEVLKPVMSIDEAMAEDAPVVHDEPVVYVAGAPDTLEDDNS
                     HAAQRGEHMIINFPIGSRPRKNIAASIHGHIGDMDKGFADADVIIERTYNSTQAQQCP
                     TETHICFTRMDGDRLVIHASTQVPWHLRRQVARLVGMKQHKVHVIKERVGGGFGSKQD
                     ILLEEVCAWATCVTGRPVLFRYTREEEFIANTSRHVAKVTVKLGAKKDGRLTAVKMDF
                     RANTGPYGNHSLTVPCNGPALSLPLYPCDNVDFQVTTYYSNICPNGAYQGYGAPKGNF
                     AITMALAELAEQLQIDQLEIIERNRVHEGQELKILGAIGEGKAPTSVPSAASCALEEI
                     LRQGREMIQWSSPKPQNGDWHIGRGVAIIMQKSGIPDIDQANCMIKLESDGTFIVHSG
                     GADIGTGLDTVVTKLAAEVLHCPPQDVHVISGDTDHALFDKGAYASSGTCFSGNAARL
                     AAENLREKILFHGAQMLGEPVADVQLATPGVVRGKKGEVSFGDIAHKGETGTGFGSLV
                     GTGSYITPDFAFPYGANFAEVAVNTRTGEIRLDKFYALLDCGTPVNPELALGQIYGAT
                     LRAIGHSMSEEIIYDAEGHPLTRDLRSYGAPKIGDIPRDFRAVLVPSDDKVGPFGAKS
                     ISEIGVNGAAPAIATAIHDACGIWLREWHFTPEKILTALEKI"
     gene            complement(9622..10401)
                     /locus_tag="RN951_002521"
     CDS             complement(9622..10401)
                     /locus_tag="RN951_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase
                     FAD-binding subunit"
                     /protein_id="HDX2527504.1"
                     /translation="MIEQFFRPDSVEQALELKRRYQDEAVWFAGGSKLNATPTRTDKK
                     IAISLQDLELDWVDWDNGALRIGAMSRLQPLRDARFIPAALREALGFVYSRHVRNQST
                     IGGEIAARQEESVLLPVLLALDAELVFGNGETLSIEDYLACPCDRLLTEIIIKDPYRT
                     CATRKISRSQAGLTVVTAAVAMTDHDGMRIALDGVASKALRLHDVEKQNLEGNALEQA
                     VANAIFPQEDLRGSVAYKRYITGVLVADLYADCQQAGEEAV"
     gene            complement(10452..11780)
                     /gene="ssnA"
                     /locus_tag="RN951_002522"
     CDS             complement(10452..11780)
                     /gene="ssnA"
                     /locus_tag="RN951_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HDX2527505.1"
                     /translation="MLILKNVTAVQLHPAKVQEGVDIAIENDVIVAIGDALTQRYPDA
                     SYKEMHGRIVMPGIVCSHNHFYSGLSRGIMANIAPCPDFISTLKNLWWRLDRALDEES
                     LYYSGLICSLEAIKSGCTSVIDHHASPAYIGGSLSTLRDAFLKVGLRAMTCFETTDRN
                     NGIKELQEGVEENIRFARQIDEAKKAATEPYLVEAHIGAHAPFTVPDAGLEMLREAVK
                     ATGRGLHIHAAEDLYDVSYSHHWYGKDLLARLAQFDLIDSKTLVAHGLYLSKDDIALL
                     NQRDAFLVHNARSNMNNHVGYNHHLSDIRNLALGTDGIGSDMFEEMKFAFFKHRDAGG
                     PLWPDSFAKALTNGNELMSRNFGAKFGLLEAGYKADLTICDYNSPTPLLADNIAGHIA
                     FGMGSGSVHSVMVNGVMVYEDRQFNFDCDSIYAQARKAAASMWRRMDALA"
     gene            complement(11783..14881)
                     /gene="ygfK"
                     /locus_tag="RN951_002523"
     CDS             complement(11783..14881)
                     /gene="ygfK"
                     /locus_tag="RN951_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenate reductase subunit YgfK"
                     /protein_id="HDX2527506.1"
                     /translation="MGDIMRPIPFEELLTRIFDEYQQQRSIFGIPEQQFYSPVKGKTV
                     SVFGETCATPVGPAAGPHTQLAQNIVTSWLTGGRFIELKTVQILDRLELEKPCIDAED
                     ECFNTEWSTEFTLLKAWDEYLKAWFALHLLEAMFQPSDSGKSFIFNMSVGYNLEGIKQ
                     PPMQQFIDNMMDASDHPKFAQYRDTLNKLLQDDAFLARHGLQEKRESLQALPARIPTS
                     MVQGVTLSTMHGCPPHEIEAICRYMLEEKGLNTFVKLNPTLLGYARVREILDVCGFGY
                     IGLKEESFDHDLKLTQALEMLERLMALAKEKSLGFGVKLTNTLGTINNKGALPGEEMY
                     MSGRALFPLSINVAAVLSRAFDGKLPISYSGGASQLTIRDIFDTGIRPITMATDLLKP
                     GGYLRLSACMRELEGSDAWGLDHVDVERLNRLAADALTMEYTQKHWKPEERIEVAEDL
                     PLTDCYVAPCVTACAIKQDIPEYIRLLGEHRYADALELIYQRNALPAITGHICDHQCQ
                     YNCTRLDYDSALNIRELKKVALEKGWDEYKQRWHKPAGSGSRHPVAVIGAGPAGLAAG
                     YFLARAGHPVTLFEREANAGGVVKNIIPQFRIPAELIQHDIDFVADHGVKFEYGCSPD
                     LTVEQLKNQGFHYVLIATGTDKNSGVKLAGDNQNVWKSLPFLREYNKGTALKLGKHVV
                     VVGAGNTAMDCARAALRVPGVEKATIVYRRSLQEMPAWREEYEEALHDGVEFRFLNNP
                     ERFDADGTLTLRVMSLGEPDEKGRRRPVETNETVTLLVDSLITAIGEQQDTEALNAMG
                     VPLDKNGWPDVDHNGETRLTDVFMIGDVQRGPSSIVAAVGTARRATDAILSRENIRSH
                     QNDKYWNNVNPAEIYQRKGDISITLVNSDDRDAFVAQEAARCLECNYVCSKCVDVCPN
                     RANVSIAVPGFQNRFQTLHLDAYCNECGNCAQFCPWNGKPYKDKITVFSLAQDFDNSS
                     NPGFLVEDCRVRVRLNNQSWVLNIDSEGQFNNVPPELNDMCRIISHVHQHHHYLLGRV
                     EV"
     gene            complement(15203..15781)
                     /gene="mocA"
                     /locus_tag="RN951_002524"
     CDS             complement(15203..15781)
                     /gene="mocA"
                     /locus_tag="RN951_002524"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HDX2527507.1"
                     /translation="MSAIDCIITAAGLSSRMGQWKMMLPWQQGTILDTSIKNALQFCS
                     RIILVTGYRGNELHERYANQSNITIIHNPDYAQGLLTSVKAAVPAVQTEHCFLTHGDM
                     PTLTIDIFRKIWSLRNDGAILPLHNGIPGHPILVSKPCLMQAIQRPNVTNMRQALLMG
                     AHYSVEIENAEIILDIDTPDDFITAQKRYTKI"
     gene            15884..16654
                     /gene="yqeC"
                     /locus_tag="RN951_002525"
     CDS             15884..16654
                     /gene="yqeC"
                     /locus_tag="RN951_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417352.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HDX2527508.1"
                     /translation="MKSIVDPSALVIDLGAQKRPTVISVVGAGGKTSLLFWLAELLQA
                     SGRRVLITTTTHMFMPTSHWPVVFCRDPAMLPHASLTSPISFCFHSWKANQGKVQGFT
                     PEAIDALVQRPECDVILIEADGSRGMPLKAPDEHEPCIPKSSCCVIAVMGGHTLGAKV
                     STENVHRWSQFADITGLTPDATLQLSDLVALVRHPQGAFKNVPQGCRRVWFINRFSQC
                     ENAIAQSELLQPLQQHDVEAIWLGDIQEHPAIARRFVN"
     gene            16702..18327
                     /locus_tag="RN951_002526"
     CDS             16702..18327
                     /locus_tag="RN951_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HDX2527509.1"
                     /translation="MNIFTEAAKLEEQNCPFAMAQIVDSRGSTPRHSAQMLVRADGSI
                     VGTIGGGMVERKVIEESLQALQERKPRLFHGRMARNGADAVGSDCGGAMSVFISVHGM
                     RPRLVLIGAGHVNRAIAQSAALLGFDIAVADIYRESLNPELFPPSTTLLHAESFGAAV
                     EALDIRPDNFVLIATNNQDREALDKLIEQPIAWLGLLASRRKVQLFLRQLREKGVAEE
                     HIARLHAPVGYNIGAETPQEIAISVLAEILQVKNNAPGGLMMKPSHPSGHQLVVIRGA
                     GDIASGVALRLYHAGFKVIMLEVEKPTVIRCTVAFAQAVFDGEMTVEGVTARLATSSA
                     EAMKLTERGFIPVMADPACSLLDELKPLCVVDAILAKQNLGTRADMAPVTIALGPGFT
                     AGKDCHAVIETNRGHWLGQVIYSGCAQENTGVPGNIMGHTTRRVIRAPAAGIMRSNVK
                     LGDLVKEGDVIAWIGEHEIKAPLTGMVRGLLNDGLAVVGGFKIGDIDPRGETADFTSV
                     SDKARAIGGGVLEALMMLMHQGVKATKEVLEVA"
     gene            complement(18368..19300)
                     /gene="arcC"
                     /locus_tag="RN951_002527"
     CDS             complement(18368..19300)
                     /gene="arcC"
                     /locus_tag="RN951_002527"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HDX2527510.1"
                     /translation="MSKKIVLALGGNALGDDLAGQMKAVKITSQAIVDLIAQGHEVIV
                     THGNGPQVGMINQAFEAAAKTEAHSPMLPMSVCVALSQGYIGYDLQNALREELLSRGI
                     NKPVATLVTQVEVDANDPAFLNPTKPIGSFFTEQEAEQLTKQGYTLKEDAGRGYRRVV
                     ASPKPVDIIEKETVKALVDAGQVVITVGGGGIPVIREGNHLRGASAVIDKDWASARLA
                     EMIDADMLIILTAVEKVAINFGKENEQWLDRLSLSDAERFIEEGHFAKGSMLPKVEAA
                     ASFARSRAGREALITVLSKAKEGIEGKTGTVICQ"
     gene            complement(19348..20733)
                     /gene="hyuA"
                     /locus_tag="RN951_002528"
     CDS             complement(19348..20733)
                     /gene="hyuA"
                     /locus_tag="RN951_002528"
                     /EC_number="3.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311773.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-phenylhydantoinase"
                     /protein_id="HDX2527511.1"
                     /translation="MRVLIKNGTVVNADGQAKQDLLIESGIVRQLGNNISPQLPYEEI
                     DATGCYVFPGGVDVHTHFNIDVGIARSCDDFFTGTRAAACGGTTTIIDHMGFGPNGCR
                     LRHQLEVYRGYAAHKAVIDYSFHGVIQHINHAILDEIPMMVEEGLSSFKLYLTYQYKL
                     NDDEVLQALRRLHESGALTTVHPENDAAIASKRAEFIAAGLTAPRYHALSRPLECEAE
                     AIARMINLAQIAGNAPLYIVHLSNGLGLDYLRLARANHQPVWVETCPQYLLLDERSYD
                     TEDGMKFILSPPLRNVREQDKLWCGISDGAIDVVATDHCTFSMAQRLQISKGDFSRCP
                     NGLPGVENRMQLLFSSGVMTGRITPERFVELTSAMPARLFGLWPQKGLLAPGSDGDVV
                     IIDPRQSQQIQHRHLHDNADYSPWEGFTCQGAIVRTLSRGETIFCDGTFTGKAGRGRF
                     LRRKPFVPPVL"
     gene            complement(20786..21997)
                     /locus_tag="RN951_002529"
     CDS             complement(20786..21997)
                     /locus_tag="RN951_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HDX2527512.1"
                     /translation="MAKNIPFKLILEKAKDYQADMTRFLRDMVAIPSESCDEKRVVHR
                     IKEEMEKVGFDKVEIDPMGNVLGYIGHGPRLVAMDAHIDTVGIGNIKNWDFDPYEGME
                     TDELIGGRGTSDQEGGMASMVYAGKIIKDLGLEDEYTLLVTGTVQEEDCDGLCWQYII
                     EQSGIRPEFVVSTEPTDCQIYRGQRGRMEIRIDVQGVSCHGSAPERGDNAIFKMGPIL
                     GELQELSQRLGYDEFLGKGTLTVSEIFFTSPSRCAVADSCAVSIDRRLTWGETWEGAL
                     DEIRALPAVQKANAVVSMYNYDRPSWTGLVYPTECYFPTWKVEEDHFTVKALVNAYEG
                     LFGKAPVVDKWTFSTNGVSIMGRHGIPVIGFGPGKEPEAHAPNEKTWKSHLVTCAAMY
                     AAIPLSWLATE"
     gene            complement(22055..23251)
                     /gene="dpaL"
                     /locus_tag="RN951_002530"
     CDS             complement(22055..23251)
                     /gene="dpaL"
                     /locus_tag="RN951_002530"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HDX2527513.1"
                     /translation="MSVFSLKIDIADNKFFNGETSPLFSQSQAKLARQFHQKIAGYRP
                     TPLCALDDLANLFGVKKILVKDESKRFGLNAFKMLGGAYAIAQLLCEKYHLDIETLSF
                     EHLKNAIGEKMTFATTTDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILNLGAE
                     CIVTDMNYDDTVRLTMQHAQQHGWEVVQDTAWEGYTKIPTWIMQGYATLADEAVEQMR
                     EMGVTPTHVLLQAGVGAMAGGVLGYLVDVYSPQNLHSIIVEPDKADCIYRSGVKGDIV
                     NVGGDMATIMAGLACGEPNPLGWEILRNCATQFISCQDSVAALGMRVLGNPYGNDPRI
                     ISGESGAVGLGVLAAVHYHPQRQSLMEKLALNKDAVVLVISTEGDTDMKHYREVVWEG
                     KHAVAP"
     gene            complement(23309..24496)
                     /gene="ygeW"
                     /locus_tag="RN951_002531"
     CDS             complement(23309..24496)
                     /gene="ygeW"
                     /locus_tag="RN951_002531"
                     /EC_number="2.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311770.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="knotted carbamoyltransferase YgeW"
                     /protein_id="HDX2527514.1"
                     /translation="MKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAAL
                     KALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIAHGE
                     TVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQC
                     DIDHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFG
                     MDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKV
                     MEQRTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELTRDGEALYMHCLPADI
                     SGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQE
                     RVK"
     gene            24975..26753
                     /locus_tag="RN951_002532"
     CDS             24975..26753
                     /locus_tag="RN951_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HDX2527515.1"
                     /translation="MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLCRVAG
                     TGAYGKFLGRQLSGNSRLLRHVLETKTEKVVTQSRFDPLCEGCDSKENCREKAFLGTP
                     VILQDRCVGVISLIAVTHEQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISK
                     IFATMIDNMDQGVLVVDDESRVQFVNQTALKTLGVVQNNIIGKPIRFRPLTFESNFTH
                     GHMQHIVSWDDKSELIIGQLHNIQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGEC
                     RVMRQLKRLISRIAPSPSSVMVVGESGTGKEVVARAIHKLSGRRNKPFIAINCAAIPE
                     QLLESELFGYVKGAFTGASANGKTGLIQAANTGTLFLDEIGDMPLMLQAKLLRAIEAR
                     EILPIGASSPIQVDIRIISATNQNLAQFIAEGKFREDLFYRLNVIPITLPPLRERQED
                     IELLVHYFLHLHTRRLGSVYPGIAPDVVEILRKHRWPGNLRELSNLMEYLVNVVPSGE
                     VIDSTLLPPNLLNNGTTEQSDVTEVSEAHLSLDDAGGTALEEMEKQIIREALSRHNSK
                     KQVADELGIGIATLYRKIKKYELLNT"
     gene            complement(26793..27272)
                     /gene="xdhC"
                     /locus_tag="RN951_002533"
     CDS             complement(26793..27272)
                     /gene="xdhC"
                     /locus_tag="RN951_002533"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase iron sulfur-binding
                     subunit XdhC"
                     /protein_id="HDX2527516.1"
                     /translation="MNHSETITIECTINEMPFQLHAAPGTPLSELLREQGLLSVKQGC
                     CVGECGACTVLVDGTAIDSCLYLAAWAEGKEIRTLEGEAKGGKLSHVQQAYAKSGAVQ
                     CGFCTPGLIMATTAMLAKPREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK"
     gene            complement(27269..28147)
                     /gene="xdhB"
                     /locus_tag="RN951_002534"
     CDS             complement(27269..28147)
                     /gene="xdhB"
                     /locus_tag="RN951_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase FAD-binding subunit XdhB"
                     /protein_id="HDX2527517.1"
                     /translation="MFDFASYHRAATLADAINLLADNPQAKLLAGGTDVLIQLHHHND
                     RYRHIVDIHNLAELRGITLAEDGSLRIGSATTFTQLIEDPITQRHLPALCAAATSIAG
                     PQIRNVATYGGNICNGATSADSATPTLIYDAKLEIHSPRGVRFVPINGFHTGPGKVSL
                     EHDEILVAFHFPPQPKEHAGSAHFKYAMRDAMDISTIGCAAHCRLDNGNFSELRLAFG
                     VAAPTPIRCQHAEQTAQNAPLNLQTLEAISESVLQDVAPRSSWRASKEFRLHLIQTMT
                     KKVISEAVAAAGGKLQ"
     gene            complement(28158..30455)
                     /gene="xdhA"
                     /locus_tag="RN951_002535"
     CDS             complement(28158..30455)
                     /gene="xdhA"
                     /locus_tag="RN951_002535"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase molybdenum-binding
                     subunit XdhA"
                     /protein_id="HDX2527518.1"
                     /translation="MEAREATATGESCMRVDAIAKVTGRARYTDDYVMAGMCYAKYVR
                     SPIAHGYAVSINDEQARSLPGVLAIFTWEDVPDIPFATAGHAWTLDENKRDTADRALL
                     TRHVRHHGDAVAIVVARDELTAEKAAQLVSIEWQELPVITTPEAALAEDAAPIHNGGN
                     LLKQSTMSTGNVQQTIDAADYQVQGHYQTPVIQHCHMESVTSLAWMEDDSRITIVSST
                     QIPHIVRRVVGQALDIPWSCVRVIKPFVGGGFGNKQDVLEEPMAAFLTSKLGGIPVKV
                     SLSREECFLATRTRHAFTIDGQMGVNRDGTLKGYSLDVLSNTGAYASHGHSIASAGGN
                     KVAYLYPRCAYAYSSKTCYTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVEI
                     RLRNAAREGDANPLTGKRIYSAGLPECLEKGRKIFEWEKRRAECQNQQGNLRRGVGVA
                     CFSYTSNTWPVGVEIAGARLLMNQDGTINVQSGATEIGQGADTVFSQMVAETVGVPVS
                     DVRVISTQDTDVTPFDPGAFASRQSYVAAPALRSAALLLKEKIIAHAAVMLHQSAMNL
                     TLIKGHIVLVERPEEPLMSLKDLAMDAFYHPERGGQLSAESSIKTTTNPPAFGCTFVD
                     LTVDIALCKVIINRILNVHDSGHILNPLLAEGQVHGGMGMGIGWALFEEMIIDAKSGV
                     VRNPNLLDYKMPTMPDLPQLESAFVEINEPQSAYGHKSLGEPPIIPVAAAIRNAVKMA
                     TGVAINTLPLTPKRLYEEFHLAGLI"
     gene            30870..31625
                     /locus_tag="RN951_002536"
     CDS             30870..31625
                     /locus_tag="RN951_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311765.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HDX2527519.1"
                     /translation="MSAGRLNKKSLGIVMLLSVGLLLAGCSGSKSSDTGTYSGSVYTV
                     KRGDTLYRISRTTGTSVKELARLNGISPPYTIEVGQKLKLGGAKSSSSTRKSTAKSTT
                     KTASVTPSSAVPKSSWPPVGQRCWLWPTTGKVIMPYSTADGGNKGIDISAPRGTPIYA
                     AGAGKVVYVGNQLRGYGNLIMIKHSEDYITAYAHNDTMLVNNGQSVKAGQKIATMGST
                     DAASVRLHFQIRYRATAIDPLRYLPPQGSKPKC"
     gene            31704..31777
                     /locus_tag="RN951_002537"
     tRNA            31704..31777
                     /locus_tag="RN951_002537"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31736..31738,aa:Gly,seq:ccc)
     gene            31912..33543
                     /locus_tag="RN951_002538"
     CDS             31912..33543
                     /locus_tag="RN951_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000935135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDX2527520.1"
                     /translation="MLKSRTYLYQRNGVFYIRLRMKTTSRLTASLPSHNRYKLASVSL
                     RTKDRRTAMAHSRHIKSALKAIHADNPNASYEELREHLKTIVEWELSVSRDDLNDPES
                     YQLYVDQYDDIKSNLREAVATERLTVDQHHYINDVIGVLKACQDRLKGDNSGLLSYLE
                     PETGSLRPSVSLSVSSEPEVPEPLVTLERVTKALTLASLIEQYEQENAQNWKPATLSE
                     NRASHSTLIEIFDYLDIQDVGKATRADMLRVREVLQQLPKNRKQRFKDIPLSDLLNRE
                     SKTDCLDVVTINNKYLIKMAAVFKWAVRNDLIAKNLTEGLELKVPQRKASDARDAFSP
                     EQVRQLLVAAKAYSQKTSGKPYHYYVTALAAITGARLNEVAQLQVKDVRTTEAGTVFI
                     HINEDDSSLPGKSIKNAHSDRCVPLVDGAYGFVLADFMSLVEDRRKTAGDNAMVFDGL
                     KLMKNGYGEQVSKWFNRTLLPKVLADRSGLAFHSFRHTVATQLKQHGVELAYAQAIMG
                     HSSGSITYDRYAKEVEVDRLVNVMAGVYKETGLNG"
BASE COUNT         8192 a         8356 c         8708 g         8361 t
ORIGIN      
        1 gggatgcaaa tgaataagtt tattgctgct gaagctgcgg aatgtatagg ctgtcatgct
       61 tgtgaaattg cctgtgcggt ggcacacaat caagaaaact ggccgctgag tcacagtgac
      121 tttcgaccgc gtatccacgt tgtagggaaa ggccaggctg cgaatccggt ggcctgccat
      181 cactgcaaca atgccccttg cgttacggct tgtccggtta atgctctgac tttccagtcc
      241 gatagcgtac aactggacga gcaaaaatgt attggttgta aaagatgcgc aatcgcttgc
      301 ccctttggcg tcgttgagat ggtcgatacg attgcgcaga aatgcgacct ttgtaaccag
      361 cgcagttccg gcacgcaagc ctgtattgaa gtttgcccaa cacaggcgtt acgactgatg
      421 gacgataaag ggttgcagca gataaaggtg gcccgccagc gcaaaacggc agcaggaaaa
      481 gcgtcatcag acgctcagcc atctcgcagt gcagcgttgc tccccgttaa ctcgcgtaaa
      541 ggcgcagata aaatttcagc gagtgaacgg aaaacccact ttggcgaaat atattgcggg
      601 ctggatccac aacaagcgac ttatgagagt gaccgctgtg tttattgtgc cgaaaaagct
      661 aactgcaact ggcattgccc gctgcataac gctattccgg attacatccg tctggtacag
      721 gaaggaaaga ttattgaagc ggcagaactt tgccaccaga ccagttcctt accagaaatt
      781 tgcggcaggg tatgtccaca ggaccgtctt tgtgaaggcg catgtacttt gaaagatcac
      841 tcgggcgcag tctctatcgg taatctggaa cgctacatca ccgataccgc gctggcgatg
      901 ggctggcgtc ccgatgtcag caaagttgtt ccccgtagcg aaaaagtggc ggtgattggc
      961 gctgggcctg cagggttagg gtgtgctgat attctggcgc gcgcaggagt tcaggtcgat
     1021 gtctttgatc gccatccaga aattggcggt atgctgactt ttggcattcc tcctttcaaa
     1081 ctcgataaaa cggtattaag ccagcggcga gagatattca ccgcaatggg aatcgacttt
     1141 catcttaact gtgaaattgg ccgcgatatt acctttagcg atttaacttc tgaatatgat
     1201 gcagttttca tcggcgtggg gacttacggg atgatgcgag cagatctgcc gcatgaagat
     1261 gcgcccggtg tcattcaggc tctaccgttc ctgactgccc atacccgcca gctcatggga
     1321 ttgccggagt ctgaagagta tccgctgacg gacgtggaag gtaagcgagt cgtggtattg
     1381 ggcggtggcg atacgacaat ggattgtttg cggacttcca tccgcctcaa tgccgccagc
     1441 gtgacctgcg cgtatcgtcg tgatgaagtc agtatgccgg gctcgcgcaa agaggtggtt
     1501 aatgcgcgcg aggaaggtgt cgagtttcag ttcaatgttc aaccgcaata tatcgcttgt
     1561 gacgaagatg ggcgtttaac tgcggtgggc ctgattcgta ccgccatggg tgagccgggg
     1621 ccggatggtc gccgtcgtcc tcgtccggta gcgggttcag agtttgaatt gcccgccgat
     1681 gttctgatta tggcctttgg tttccaggcg catgccatgc cgtggttgca gggcagcgga
     1741 attaaactcg ataaatgggg cctgattcaa accggtgacg tcgggtattt acctacccag
     1801 acgcatctga aaaaagtctt tgctggtggt gatgcagttc atggcgcgga tctggttgtc
     1861 actgcaatgg ccgcaggaag gcaggcggcg cgcgatatgt taactctgtt tgatacgaag
     1921 gcatcgtgat gaaatcgtta attatcgtta atccggctga ctgtattggc tgccgtactt
     1981 gtgaagtagc ctgtgtggtc gctcaccctt cagaacagga gttgaatgcc gatgtctttt
     2041 taccccggct gaaggtacag cgactggaca gcatcagtgc gccggtgatg tgccatcagt
     2101 gtgaaaacgc cccttgtgtt ggcgcttgcc ccgtgggggc gctgacgatg ggcgagcagg
     2161 tggtgcagac caattctgcc cgttgtattg gctgtcagag ttgcgtcagt gcgtgcccgt
     2221 ttggaatgat caccattcag tcgttgccgg gggatacccg acaacaaatt gtgaaatgcg
     2281 atctctgtga acagcgggaa gaggggccag cctgcgttga atcttgccca acacaggcgc
     2341 tgcagttgct tactgaaaga gaactcaggc gagtccgcca gcagcgtatt gttgccagcg
     2401 gtgagaatcc tctctgaaag aaatctccgc gctgaaaggc gcggagaatc tattagattg
     2461 cccaaccacc cgcgtaaaat gcgaccagtg cggcagtaat gatcaccgta ccaatattca
     2521 gcttttgcca ttcgcgtgca aagacgcggc ctacgaccag tgtcacaaag cccagcataa
     2581 taccggtaac gatattacaa gtcagaacga tgaacacggc acacaccagg ccagccatag
     2641 cgtcaataaa atcattgaaa tccagcttcg agacgttact taacatcagc aaacctacgt
     2701 acatcagagc gggtgcagtg gcgtaaccag ggatcaaaaa tgacagcggt gataaaaaca
     2761 gaattaacag gaataacgcc cccactacgg ttgcggttaa acctgtttta cccccggcgg
     2821 cggttcctgc cgctgattcg atataaaccg ctgcgggcgc tgcgcccacc aggccggaga
     2881 atattgaact tactgagtca ctggtcaggg ctttgccgcc gttgatgatc tggttgtctt
     2941 tatccaacaa attcgcctga ccggcgacgg cacggatggt gccagtagcg tcgaacactg
     3001 cggtcatcac caatgccagt acactcggaa gtacagttgg ctggagtgca cccataatat
     3061 cgaggctgaa aatcagagac ttaccatctt cgccagtcag gcttggcatc gccaccagac
     3121 cgtggtattt caccgctggg tcaaagatta agccgatgat cgaaattgca ataatcacca
     3181 acaagatccc gccgggtacg cgacacttct ccaggccgaa gatgaccgcc agccccagca
     3241 agctcatcat caccgggaag gaggtaaacg caccgagcgc cactggcaag ccttcaatcg
     3301 ggtttttgat aaccataccc acaccgttag cagcaatcag cagcagaaac agcccgatac
     3361 cgatacctgt accgtgagcg atacccatcg gcaaattacg taagatccag gtacgcacac
     3421 cggttacgga aatggcggtg aagatgacgc ccatcagaaa taccgcgccc agtgcgacag
     3481 gaacgctaat ttgttgcccg agtaccagac tgaatgcggt aaacgccgtc aaggaaatcg
     3541 cgcaaccaat cgccattggc aaattagccc ataatcccat cagcaacgag ccgaagcccg
     3601 cgaccagaca ggtggcaaca aacacagctg cgggaggaaa acctgctttg cccagcattc
     3661 ccggaacgac gataacggaa taaaccatgg ccagaaaggt cgttaagcca gccagtactt
     3721 cctgacgaac ggtactgcca cgagcggtaa ttttaaaata attatccagc gcgccctgtg
     3781 gctttggtgc gtccggtgtt tgtaggatgt ctccagacat aatgatgtcc tcacgaggat
     3841 gttaaagttt tattattagt tgcgttcgta caccagacga ccatcaacgt aggtgcggta
     3901 gatcgaacgg tcatcgccca acgtcatcat cacgaacaat ttgtcgacta aagaaacaga
     3961 gttgtcatag cgcagctgct gtagcggagt ggcggtgggt tccatcacca cgaaatcagc
     4021 ctctttgcca ggtaaaaagt tgccaatcaa atcgtcaagg cccagagatt tcgctccgcc
     4081 gagcgtggcc aggtaaaacg cttcatatgc cgagaggcga tagccttgta attgcaatac
     4141 tttgtaggct tcgttcagcg tttgcagcat gttgaaagtg gttccggcac cgatatccgt
     4201 tcccatgccc actttaactt tcttctgcca tgcttttttc aagttgaata agccgctgcc
     4261 gaggtaaagg ttggaggtcg gacagaaagc aatgctggat ttggtttcgc tgagacgatc
     4321 ccactctttt tcttcgagat ggacgcagtg agcaaagaca cagtttttac cggtcaggcc
     4381 gtactgatgg taaacatcca gataaccatc atggtcagga taaagcgatt tcacccaggc
     4441 aatttcatct ttgttttcac agagatgggt atgtacccac gtatccggat attcttcttt
     4501 caggcgttgc gccatcgcca tctgttcagg agatgaggtc ggggcgaagc gtggcgtaat
     4561 cgcatatagc agacgaccat ttttgtgcca gcgttcgatc agttctttgc tttggtgata
     4621 gctgctttcg gcagtgtcga gcagataatc cggtgcgttg cggtccatca tcaccttacc
     4681 ggcaatcata cgcatattga tatgactggc ggcttcaaac agcgcatcaa cagattgcgg
     4741 atgaacagtg ccaaacacca gcgccgtggt ggttccgtta cgtaaaagct gcttgatgaa
     4801 gaacgccgac atttcgcggg cgtactctaa atcctcataa cgacgttcag tagggaaggt
     4861 gtgtttattc aaccactcca gcaattgctc accataggcc cccaccattt cactttgcgg
     4921 ataatggata tgtgtatcga caaagcccgg tactatcagt ttgccgcgat agtcgcgcac
     4981 gcgaatggtg tcaggaattt gatgctttcc gttttcccat tcgccaaacc attccacttt
     5041 tccctgttta atgagtaata aaccatcctc aataaaccgc agcgcagagg caatctcttc
     5101 cgggttatcg atcgtacggg tgacatcaat aaaactgcct cgtaccgctt ttaacgtgtg
     5161 ttctcctgac atcattgact cctttactgt taatccatct cttccgctga ggtaatacca
     5221 ggcagaacgt tttcctgtcg gtagccacca gggaggataa tatttaataa aatcgcagtt
     5281 aacccgccag cacaaatagg gttttcaact aatacataaa tagaggctgg caatatttta
     5341 aaaatttcgg gatcgtagga gacgccaagc cctaaaccta aagaagtggc gacaataagt
     5401 gtttcacggc gctttaaacc gttggtgatg atgatgcgaa tccctgcgat ggcaatcatg
     5461 gaaaacatca acgtcattgc gcctcccaga actgccgagg gaatggtcgt gaagaagccg
     5521 ccaatcatcg gaaataagcc gaggataacc agcattaccg cgatggttcg cccgacataa
     5581 cgtgaagcga cgccagtcat ctgaataacc ccattatttt gcgcaaacgt ggttaatggt
     5641 aatgaaccga cagcggaggc gataacagaa accagaccat ctgccagcac gccgcctttc
     5701 agccgggact gatactcttc cccctgaatg gggcggcggg aaaccattgc cgtggcggtg
     5761 atatcgccga ctgcttccag cacgctaagc agataaatcg tgccaaccac caggaactga
     5821 tggaagctaa aactaaagcc gtatttgaac ggatgcggga tggtgattaa cggcaaattg
     5881 cgcatactgc tgaaatccac catgcccagg cataacgatg cgatatagcc gacacatagc
     5941 ccaatggcga tccctcccat gcgtagcaac ggactgcgac agcagttaaa gccgatcacc
     6001 acaattaaaa ccaataaacc aacgccgaga tgttcgtaat tgccgaacgt accgctgctt
     6061 ttggctgcaa atcctccacc aaaatcgata atgccgactt taatcaggct taagccgatc
     6121 atcagtacca caataccgct gacggtaggc gtaataaccc gacgtaaata gggcaagata
     6181 aatgaagatc cgacaaccag aaatgcgcca acgaaggaga cgccgagaag cgacgacatg
     6241 attaactctt cgtgaaaacc gtcgcttttc atgctgctgc ccagcgcaat catgaccgta
     6301 acaaatgaaa aattgactga ctgaattgag agtaggccag aaccgacgat gccgtagcgg
     6361 tttacttgta accaggtacc aataccagag gcgatcatcg ccatagaaac aagataggca
     6421 gttgtttcag cggaaagctg taaggccgca cccacgatta acgcgggggt taccatcgga
     6481 acgaaaattg ccaacagatg ggtaatggca ccaacgagag cctgatgaaa gggagggcga
     6541 tcctccagtt caaatataag gtcagaacct gcatggttta tatcagacat cccttcactc
     6601 cttttaaagt aaatttgatc atctgaatta gtaaaataaa ttcccacgaa tttggggcgc
     6661 aggacgcctt gagaacggct tatctcattt tcgcagtcac tatttagtca tcgttcaaac
     6721 agagaaacag gccgccgaag cggccattta ttatttatat tttttccagc gcagtgagta
     6781 ttttctccgg tgtgaaatgc cattcgcgta accagatgcc gcatgcatcg tgaattgcgg
     6841 tagcaatcgc cggagctgcg ccatttacac cgatttccga gatcgatttc gccccgaacg
     6901 ggccgacttt atcgtcgctc ggcaccagca cagcgcggaa atcacgcgga atgtcaccaa
     6961 ttttcggtgc gccgtaactg cgtaaatcac gcgttaacgg gtgaccttcg gcgtcataaa
     7021 tgatctcttc gctcatactg tggccgatag cacgcagggt ggcaccgtag atttgtccca
     7081 acgctaactc tggattgacc ggtgtaccgc agtccagcaa ggcgtagaat ttatccaggc
     7141 ggatttcacc cgtacgcgtg ttgacggcaa cttcagcgaa gtttgcgcca tacgggaagg
     7201 cgaaatcagg cgtgatataa ctgccagttc ccaccagtga accaaagccg gtgccggttt
     7261 cgcctttatg ggcaatatcc ccgaaactaa cttcgccttt cttgccgcgc acgacgcccg
     7321 gcgttgccag ttgaacatct gccactggct cacccaacat ttgcgcgccg tggaacagaa
     7381 ttttctcccg tagattttcc gctgccaaac gcgccgcgtt acccgagaag caagtaccgg
     7441 acgaggcata tgcgccttta tcaaacaacg catgatcggt atcaccggag ataacatgca
     7501 cgtcctgcgg tgggcagtgc agcacttctg ctgccagttt cgtcactaca gtatccagac
     7561 cagtaccaat atccgcaccg ccagaatgaa cgataaaggt gccgtccgat tccagtttga
     7621 tcatgcagtt agcctgatcg atatccggga tacccgattt ctgcatgata atggcgacgc
     7681 cgcgaccgat gtgccagtca ccattttgcg gtttcggtga cgaccattgg atcatctcgc
     7741 gaccctgacg caggatctct tccagtgcac agctggcggc ggaaggaacg gaggtcggcg
     7801 ctttaccttc accgattgca ccgagaattt tcagctcttg cccttcgtgt acccggttac
     7861 gttcgataat ttccagttgg tcgatctgta actgttcagc cagttccgct aatgccatgg
     7921 tgatagcgaa gttacctttc ggtgcgccat aaccctgata agcaccattt gggcaaatgt
     7981 tgctgtagta ggtggtgacc tggaaatcga cgttatcgca cggatataac ggcagcgaca
     8041 gcgccggtcc gttacacggt acggtgagtg agtggttgcc gtaagggcca gtgttggcgc
     8101 ggaaatccat cttcactgcc gtcaggcgac catctttttt cgctcccagt ttgacggtga
     8161 ctttcgcgac gtgacgagag gtgttagcaa taaactcttc ttcacgggtg tagcggaaca
     8221 gtaccggacg cccggtcacg caggttgccc aggcgcacac ttcttccagc aggatgtcct
     8281 gtttggaacc aaaaccgccg ccaactcgct ctttaatgac atgaacttta tgctgtttca
     8341 tgcccacgag gcgcgcgacc tggcggcgta agtgccatgg tacctgggtg gaggcgtgga
     8401 taaccagacg atcgccgtcc atacgagtaa agcagatatg tgtttcagtc gggcactgct
     8461 gcgcttgcgt tgagttatag gttcgctcaa tgatcacatc ggcatcggca aagcctttgt
     8521 ccatatcgcc aatatgacca tgaatactgg cggcgatatt tttgcgaggg cgagaaccga
     8581 tcgggaagtt gatgatcata tgctcgccgc gctgggctgc atggctgtta tcgtcttcca
     8641 gagtatctgg cgcaccagca acatacacca ccggttcatc gtgcacgaca ggcgcatcct
     8701 ccgccattgc ttcgtcgatc gacattaccg gcttaagcac ttcatattca acgtcgatga
     8761 gcttcagtgc ttcgagccca atttcttcac tttctgcgac gaccgcagca acacgatcgc
     8821 cgacgtgacg cattttcttg ccgaacatac ggcggtcaag cggtgacggt tccggtgcgc
     8881 tctgaccacc cggggtatag tagatatccg ggcaattcag gtgagtaata acgtgaacga
     8941 cgcccggtaa ggcttcagct ttgctgacat ccagatgagt aatcagtgcg tgagcgtgtg
     9001 ggctacgtaa cattttaatg acgcaggcgt cagccgttac gcggtcttca acatagcagg
     9061 gtttcgcctg caccattttc gcggcatcag ttttaggata atgcttacca atgacttcta
     9121 ggtcgtcacg gaaagtcgga gcgatatcaa tggtggcctg cggattattt ttacgtgcaa
     9181 ccgccagttc aatgacctga tagtattgct gccagccagc atcgcggctg aacaaaccag
     9241 aaagcgcgtc gtcgatctct tcgcgggtag gtgcggcgat gcgatcgaga agatcggtga
     9301 taatcagagc tgcagctgga tcgttataac cagactgcac cacgccaaca tcaaccattg
     9361 cctgttgaac cagacttaac tcgttccatt tgcccagaga ttctgcggta cgaatatctg
     9421 ccttctctaa ctgtgcggca ataagcaagg acgcgttaac gatattaccg ttaaagatta
     9481 ttgcgtcaga accggcaaac ccgaaaccat catcactgtt gcgtacagag tgcattccca
     9541 tgttaaacaa cagcttttgc acgttttcgc ctggattaac ggttagctcc tgaggcgcgc
     9601 catttaaagt aaagtggatg atcatacggc ttcctcccca gcctgttggc agtcggcata
     9661 caggtcggct accagaactc ccgtgatata gcgtttatag gccacgctgc cccgcaaatc
     9721 ttcctgcggg aaaatggcgt tggcgacagc ctgttcaagt gcattgcctt ccagattttg
     9781 tttttcgaca tcatgcagac gcagtgcttt actggcgacg ccatccagcg caattcgcat
     9841 accgtcgtgg tctgtcattg caacggctgc cgtcacgacg gttaaacctg cctgagaacg
     9901 gctaattttg cgggtcgcac aggtgcgata cggatcttta atgataattt cggttagcag
     9961 gcgatcgcat gggcaggcca ggtagtcctc gattgacagc gtttcgccgt tgccaaaaac
    10021 cagttcagca tccagtgcca acaggacggg aagcagcacc gactcttcct ggcgggcggc
    10081 gatttcacca ccaatggtcg actgattacg aacatggcgt gagtaaacaa aaccgagggc
    10141 ttcacgcagc gctgcaggaa taaatcgcgc atcacgcagt ggctgcaagc gagacattgc
    10201 gccaatccgc agtgcaccgt tatcccagtc aacccagtcc agttccagat cctgtaagga
    10261 aatggcaatc tttttatcgg tacgggttgg tgtagcattg agtttgctgc ccccggcgaa
    10321 ccagacggct tcatcctggt agcggcgctt cagttccagc gcctgttcga cagagtcggg
    10381 cctgaaaaat tgttcaatca tcttctttcc ttatttaacc ctcttccctg cgggaagagg
    10441 gcatctgtca tttatgccag cgcatccatc cgacgccaca tactggcagc ggcttttctg
    10501 gcttgtgcat aaatggaatc gcaatcgaag ttaaactgac ggtcttcata gaccatcaca
    10561 ccattgacca tcacgctgtg aacgctgcct gagcccatac cgaaagcgat atgcccggcg
    10621 atattgtctg ccagcagcgg cgtcggtgag ttgtaatcgc aaatggttaa atcagctttg
    10681 taaccggctt ccagaagtcc aaatttcgcg ccaaagttgc ggctcatcag ttcgttaccg
    10741 ttagtcaggg ctttggcaaa actgtcaggc cacagcggac cacccgcatc gcgatgttta
    10801 aagaaggcaa atttcatctc ttcaaacatg tccgaaccaa tgccgtccgt tcccaacgcc
    10861 agattgcgga tgtcgctaag gtgatggttg tagccgacat ggttgttcat gtttgaacgg
    10921 gcgttatgca ccaggaacgc atcgcgctga ttgagtaggg cgatgtcatc tttcgacaag
    10981 tacagcccat gagcgaccag cgttttgcta tcgatgagat cgaattgcgc cagtcgtgcc
    11041 agcaggtctt tgccgtacca gtggtgactg taggaaacgt cgtaaaggtc ttccgcagcg
    11101 tgaatatgca aaccacggcc tgtggctttc acggcttcac gtagcatctc cagaccggca
    11161 tctggcacgg taaacggcgc gtgagcaccg atatgtgctt ccaccagata cggctcggtt
    11221 gctgctttct tcgcctcatc aatctgacgg gcgaagcgga tgttttcttc tacaccttcc
    11281 tgcaactctt tgatgccgtt gttacggtca gtagtttcaa aacaggtcat cgcgcgcagg
    11341 ccaactttta aaaatgcgtc gcgcaatgtg gagagcgacc cgccgatata cgccggagag
    11401 gcatggtgat cgataaccga tgtacatccg ctcttaatcg cttctaggga acaaatcagc
    11461 ccgctgtaat agagcgactc ttcatcaagg gcgcgatcga gccgccacca gagatttttc
    11521 agcgttgaga tgaaatccgg gcagggggcg atgtttgcca taattccgcg ggaaagcccc
    11581 gagtaaaaat ggttgtgcga gcagacaatt cccggcatca caatccgacc atgcatctct
    11641 ttgtagctgg catcggggta gcgttgcgtc agggcatcgc cgatagcgac aatcacatca
    11701 ttttcgatag cgatatcaac gccttcctgc actttcgccg ggtgtaactg cactgcggtg
    11761 acattcttca gaatcaacat gattacacct ccacgcggcc cagcagataa tgatgatgct
    11821 ggtggacatg gctgatgatg cggcacatat cgttcagctc cggtggtacg ttgttgaact
    11881 gaccttcgct gtcgatgttt aacacccagc tttggttatt cagtcgtact cgtacccggc
    11941 aatcttccac aaggaagcct gggttgctgc tgttatcaaa gtcttgcgcc aggctgaaaa
    12001 cggtgatttt gtctttgtat ggtttaccgt tccacggaca gaactgagcg cagttgccgc
    12061 attcgttaca gtaagcgtcg aggtgcagcg tctggaatct attctggaag cctgggaccg
    12121 caatggagac gttggcgcgg ttcgggcaga catccacaca cttgctgcaa acgtagttac
    12181 attcgaggca gcgagcggct tcctgggcga caaacgcgtc acgatcgtca ctgttcacca
    12241 gagtgataga gatatcgcct ttacgttgat agatttccgc cggattgacg ttgttccagt
    12301 atttatcgtt ctggtgggaa cggatatttt cccgactaag gatggcatcg gtcgcccgac
    12361 gcgcggttcc gacagcagcg acaatggagg atggtccgcg ctgtacgtcg ccgatcataa
    12421 agacgtcagt cagacgagtt tcgccattat ggtcgacgtc tggccagccg tttttgtcca
    12481 gcggcacgcc catcgcattc agggcttcag tatcctgctg ttcaccaatg gcggtgatca
    12541 ggctgtctac aagcagtgtt actgtttcat tggtttcaac cggacgacga cgacctttct
    12601 catccggttc gccaagcgac ataacgcgca aggttaaggt gccatcagca tcgaaacgtt
    12661 ccggattatt caggaaacgg aactctacgc cgtcgtgcaa cgcttcttca tactcttcgc
    12721 gccatgcggg catctcttgt agtgaacgac ggtaaacgat cgttgctttt tctacgcctg
    12781 gaacgcgtaa cgccgcacga gcgcagtcca ttgcggtgtt acccgccccg acaacgacca
    12841 catgtttgcc cagcttgagc gctgtaccct tgttgtattc acgcaggaag gggagtgatt
    12901 tccagacatt ttggttgtca cccgccagtt tcacaccgct atttttatca gtgccggtgg
    12961 caatcagaac atagtggaag ccctgatttt ttaactgttc aacggtcaaa tcgggtgagc
    13021 agccatactc aaatttcacg ccgtgatcgg caacaaaatc gatatcgtgc tgaattaact
    13081 cagccggaat acggaactga ggaatgatat ttttcaccac gccgcccgca ttggcttcgc
    13141 gttcaaacag cgtaaccgga tggcccgctc tggcaaggaa gtaacctgct gccagacccg
    13201 ccggacctgc accaatcacg gcaaccggat ggcgtgaacc agaaccggct ggtttgtgcc
    13261 agcgttgctt atattcatcc caaccttttt ccagcgcgac ttttttcagt tcgcggatat
    13321 tcagcgcact gtcgtaatcc aggcgggtac agttgtattg gcactggtga tcgcaaatat
    13381 gaccggtaat ggcgggcaga gcgttgcgtt ggtagatgag ttccagcgcg tcggcatagc
    13441 ggtgttcgcc aagcagacgg atgtattccg gaatatcttg cttgatagcg caggcagtaa
    13501 cacagggggc aacgtagcaa tcggtcagcg gcaggtcttc tgccacttca atacgctctt
    13561 ctggcttcca gtgtttctgg gtgtattcca tggttaacgc atctgctgcc agtctgttca
    13621 gtcgttcgac gtcaacatgg tcaagtcccc aggcgtcgga gccttccagc tcgcgcatgc
    13681 aggcacttaa gcgcaaatag ccgccaggtt tcagcaggtc ggttgccata gtaatagggc
    13741 gaatacctgt atcaaaaata tcgcggatag tcagctgact ggcaccaccg gaataagaaa
    13801 tgggcagttt gccgtcaaag gcgcgagaga gaactgctgc aacattgatg gagagcggga
    13861 acagcgcacg gcctgacata tacatctctt caccaggcag tgcgccttta ttgttgatgg
    13921 tgccgagagt gttagtcagt tttacgccaa agccgagtga tttttctttt gccagtgcca
    13981 tcaggcgttc cagcatttcc agtgcttgcg tcagcttgag gtcgtgatca aatgactctt
    14041 cttttaagcc tatgtaaccg aaaccgcaga catcgaggat ctcacgaaca cgcgcgtatc
    14101 ccagtaaggt cgggttaagt ttcacaaagg tgttgagccc tttttcttcc agcatgtagc
    14161 ggcaaatggc ttcgatttca tgcggaggac agccgtgcat ggtggagagg gtgacgccct
    14221 gcaccatact ggtggggatg cgagcgggta aggcttgcaa gctttcgcgt ttttcctgca
    14281 atccgtggcg ggctaaaaat gcgtcatcct ggagtaattt attcagcgta tcgcgatatt
    14341 gcgcgaattt cggatggtca gatgcgtcca tcatattgtc gatgaactgt tgcattggcg
    14401 gttgcttaat accttcgagg ttgtaaccga cgctcatatt aaagatgaac gatttaccgg
    14461 aatcagaagg ctggaacatc gcttcgagaa ggtgcagggc aaaccaggct ttgaggtatt
    14521 catcccaggc tttaagcagg gtaaattcgg tagaccattc ggtgttaaag cactcgtctt
    14581 cggcatcgat acagggcttt tccagctcca ggcggtcaag aatttggacg gtttttagtt
    14641 cgatgaagcg tccgccagtc agccaggaag tgacaatatt ttgcgcgagc tgcgtgtgcg
    14701 ggccagcggc agggccgacg ggagtggcac aggtttcacc gaagacgcta acagttttac
    14761 cttttacagg tgagtaaaac tgttgctcgg gaataccaaa gattgagcgt tgttgttggt
    14821 attcatcaaa tatgcgcgtc aaaagttcct caaacggaat gggacgcata atatccccca
    14881 taaccctctc cttagcttat acagatatca ttgagtgacc ggtgttgaga aatccggtgg
    14941 tttaggggga tagagcaaca atcgcaccac tcttgccagg tttggcggga aatataaaaa
    15001 aatgtgaggc ggctcgaaac ttaaaggctt tttgtgaatg aactcacagg tgccaaatga
    15061 gaattaaaat cactcctgaa aattattatt gtcagcccat ttatcacttt ttctcttttc
    15121 tcaaaatcag tgattcctta tcattatgat aaagagtgct ggagagatta aatatttgaa
    15181 cgcaatcgtt taactacatt ttctaaattt tagtatacct tttttgcgct gtaataaagt
    15241 cgtccggagt atcaatatct aaaattattt ctgcattttc tatctcgacg gaataatgag
    15301 ctcccataag gagtgcctga cgcatattgg tgacattggg tcgttggatt gcctgcatca
    15361 agcatggttt tgacactaaa atcggatggc cggggatgcc attatggagt ggcagtattg
    15421 cgccatcatt tcgtaacgac cagatttttc taaaaatatc gatggtgagg gttggcatgt
    15481 caccgtgggt gagaaaacaa tgttctgttt gcactgcggg tactgcggcc tttactgatg
    15541 ttagtaaacc ctgcgcataa tctgggttgt ggataatagt gatattgctc tggttcgcat
    15601 aacgttcgtg cagttcatta ccacgatagc cggtgactaa aataattcgg ctacaaaact
    15661 gcaacgcatt tttgatactt gtatcaagaa ttgtcccctg ttgccagggt aacatcattt
    15721 tccattgccc cattcttgat gataatccgg cagcggtaat tatacagtcg atggctgaca
    15781 tagtggctcc attatttata ggggctaata acgcctgata attgcgttac ttcctgatgg
    15841 attaagttgg ggataattta tcccagagag gtcataaaga ctcgtgaaaa gtatagttga
    15901 cccatcggca ttagtcattg atttaggtgc gcagaaacgt cccactgtga tttctgttgt
    15961 tggtgctggg gggaaaacca gcttgctttt ttggctggca gaactgctcc aggctagcgg
    16021 caggcgtgtg ttaatcacga cgacgacaca tatgtttatg ccaacgtctc actggcccgt
    16081 ggttttctgt cgtgatcccg ccatgcttcc tcatgcgtct cttacatccc ccatttcatt
    16141 ttgttttcac agctggaaag cgaaccaggg aaaagtgcag ggatttacgc cagaagcgat
    16201 tgatgcactg gtgcaacgac cagagtgtga cgtaattctc attgaagcag atggctcgcg
    16261 tggaatgccg ttaaaagcgc ctgatgagca cgaaccttgc atacccaaaa gcagttgctg
    16321 cgtgattgct gtgatgggag gacatacttt gggcgcgaaa gtgagcacag aaaatgtcca
    16381 tcgctggtcg cagtttgctg atattaccgg gttaacacct gatgcaacct tgcaactgag
    16441 cgatctcgtt gcgctggttc gccaccctca gggggcgttt aaaaacgtac cgcaaggttg
    16501 tcggcgagtc tggttcatta accgtttttc tcaatgtgag aatgcgattg cacaaagcga
    16561 gctccttcaa ccgctgcaac aacacgacgt agaggcaatc tggctgggcg atatacaaga
    16621 acatcctgca atcgcgcgca gatttgtgaa ttagcggccc gggtattccg ggttactgaa
    16681 aggatatcca ttgaggttgg tatgaatatt ttcacagagg ctgcaaaact cgaagagcaa
    16741 aattgtccgt ttgcgatggc gcaaattgtt gatagccgag gctcgactcc ccgccattct
    16801 gcacaaatgt tagtgcgcgc cgatggttct atcgtcggta caattggtgg cggaatggtt
    16861 gagcggaagg tgattgaaga gtcacttcag gcattgcagg aacgtaagcc gcgattattc
    16921 catggacgta tggctcgtaa cggtgcggat gctgtcgggt cagattgtgg aggtgcaatg
    16981 tcagtattta tcagcgtcca tggtatgcgt ccacgtctgg tgttgattgg cgcggggcat
    17041 gtcaaccggg cgatagccca gagtgcggcg ctattaggat ttgatattgc cgttgccgat
    17101 atttatcgcg aaagcctcaa tcctgaacta ttccctccat caaccacgct tctccatgct
    17161 gagtcgtttg gtgcagcagt ggaagcactg gatattcgcc ctgataattt tgtcctgatt
    17221 gccacgaata atcaggatcg tgaagccctc gacaaactca ttgaacagcc cattgcatgg
    17281 ttggggttgc tggcaagtcg ccgcaaggtt cagcttttcc tgcgtcaatt gcgtgagaaa
    17341 ggcgtggctg aagaacatat tgcccgttta catgcgcccg ttggttacaa cataggtgcg
    17401 gaaacgccgc aggagatcgc catcagcgtg ctggcagaaa tattacaggt gaaaaataac
    17461 gcgccgggtg ggctgatgat gaaaccttct catccttccg gacaccagct ggtggtgatt
    17521 cgcggtgcgg gagatatcgc cagtggtgtg gcgctacgtc tgtatcatgc gggttttaaa
    17581 gtgatcatgc tggaagtgga aaaaccgaca gtgattcgtt gtaccgtggc gtttgcccag
    17641 gccgtgttcg atggcgaaat gacggtcgaa ggcgttactg ctcgcctggc aaccagctct
    17701 gcggaagcga tgaaacttac cgaacgcgga ttcatccctg tgatggcaga tcccgcctgt
    17761 tcattgcttg atgaactgaa accgctttgc gtggtggacg ctattctggc gaaacagaat
    17821 ttgggaacgc gggcagatat ggcaccagta acaatcgcgc ttgggccggg ctttactgca
    17881 gggaaggatt gtcatgcggt aattgaaaca aatcgcgggc actggctcgg tcaggtgatt
    17941 tactctggtt gtgcgcagga gaataccggt gttcctggca atattatggg gcataccacc
    18001 cgacgggtga tccgtgctcc tgctgcaggc attatgcgat ccaacgtgaa attaggcgat
    18061 ctggtgaaag agggcgatgt gattgcctgg attggtgagc atgaaattaa agcaccgttg
    18121 acggggatgg tgcgtggctt gttgaacgac ggcctggcag tggtcggtgg ttttaaaatt
    18181 ggtgatatcg atcctcgtgg tgaaacggct gatttcacca gcgtttctga taaagcccgg
    18241 gcgattggcg gcggcgtact tgaggcgtta atgatgttga tgcatcaggg cgtgaaagcg
    18301 acaaaagaag tgctggaagt ggcttaaatg aaaatggccg gatggtatta cccacccggc
    18361 cttaaaatta ctgacaaatc accgttccgg ttttgccttc aatcccctct ttcgctttgc
    18421 tcaatacggt aatcagtgct tcacgacctg cgcgagagcg agcaaacgag gcggcagctt
    18481 ccactttagg cagcatagaa cctttcgcaa aatgaccttc ttcgataaag cgttcagcat
    18541 cacttaatga caggcgatcg agccactgtt cattctcttt accgaagtta atggccactt
    18601 tttctaccgc agtcagaatg atcagcatat cggcatcaat catttctgct aaacgggcgc
    18661 tggcccagtc tttatcgata accgcgctgg caccacgcag atggttacct tcacgaataa
    18721 caggaatacc accaccgcca acggtgatca ccacctggcc tgcatctacc agagctttaa
    18781 ccgtttcttt ttcaataata tcaaccggtt ttggcgaggc aacaacacgg cgatagccgc
    18841 gaccagcatc ttctttcaga gtgtaaccct gttttgtcag ttgctctgct tcttgctcgg
    18901 taaagaacga accgatcggc ttggtcgggt tgaggaatgc cggatcgtta gcgtcgactt
    18961 cgacctgagt aaccagcgtt gctaccggtt tattaatgcc ccgagaaagc agttcttctc
    19021 ttaaggcgtt ttgtagatcg taaccaatat aaccctggct taaggcaacg cagacagaca
    19081 tcggcagcat tggcgagtgc gcttcagttt ttgcagcagc ttcaaaggcc tggttaatca
    19141 tgcccacctg cggcccgtta ccatgagtga cgataacttc atgtccctgg gcaattaaat
    19201 caacaattgc ctgagaagta atttttaccg ctttcatttg tccggccagg tcatcgccca
    19261 gcgcattccc gcccagggcg agaacaattt tcttactcat ttttcctcac tcatcattct
    19321 tgattgtgta tagatccctg acagtggtta gagcacggga gggacaaacg gtttgcgtcg
    19381 caggaaacga cctcgcccgg ctttgcctgt aaaggtgccg tcacagaaaa tcgtttcacc
    19441 acgggataag gttctgacaa tcgcgccctg acaggtaaaa ccctcccatg gcgagtagtc
    19501 ggcgttgtcg tggagatggc gatgctgaat ttgttggctc tgacgtgggt cgataatcac
    19561 cacgtcgcca tcggaaccgg gcgctaataa tcctttttgc ggccacaggc caaacagcct
    19621 ggcgggcatt gcgctggtta attcaacaaa gcgttccggt gttatacgtc ccgtcatcac
    19681 gccactggaa aacagtaact gcatgcggtt ttccacaccg ggtaagccat ttgggcagcg
    19741 actgaaatcg cctttagaaa tttgcaggcg ttgagccatc gagaaggtgc agtgatcggt
    19801 cgccaccacg tcaatcgcac catcgctgat gccacaccac agtttgtcct gctcgcgtac
    19861 gttacgcagc ggtgggctaa gaatgaactt catgccgtct tctgtatcgt aactgcgttc
    19921 gtccaacagg aggtattgtg ggcaggtttc aacccagact ggctggtgat tcgcacgggc
    19981 aagacgcaga taatccagac ctaagccgtt agacaggtgc acgatataga gcggggcgtt
    20041 accggcaatt tgtgccaggt taatcatgcg ggcgatggct tccgcttcgc attccagagg
    20101 gcgactcaag gcatgatagc gcggcgcggt taaccctgcg gcgataaatt ccgcccgctt
    20161 gctggcgata gccgcatcat tttccgggtg cacggtggtc agcgcgccgg attcatgcag
    20221 acggcgtaat gcctgcaaaa cctcgtcatc gttgagtttg tattgatagg ttaaatagag
    20281 tttaaaactg ctcagtcctt cctcgaccat catcgggatt tcgtcgagga ttgcgtgatt
    20341 aatgtgctgg atcacaccgt gaaagctgta atcgatgacc gctttatggg cggcataacc
    20401 acgataaacc tctagttgat ggcgtaaccg acagccgttt gggccaaatc ccatatggtc
    20461 aataatggtt gttgtaccgc cacacgcagc tgcgcgggta ccggtaaaaa aatcatcaca
    20521 actgcgcgcg atgccgacat caatattgaa atgcgtatgg acatccacgc cgccagggaa
    20581 aacgtaacag ccagtggcat caatttcttc atacgggagc tgcggcgaaa tattgttgcc
    20641 caactggcga acaatcccgc tttcaatcag caaatcctgt ttggcttgtc catctgcgtt
    20701 aacgacagtg ccgtttttga tcaatacgcg catagcaaac tccaaaaacc ctccggcgaa
    20761 ccggagggga ataagtgaag agtaattact ctgttgccag ccagcttaac gggattgcag
    20821 cgtacatcgc ggcacaggtc accaggtgag atttccaggt tttttcgtta ggtgcatgcg
    20881 cttcaggttc tttacccggg ccaaagccga tcaccggaat gccgtgacgg cccatgatag
    20941 atacgccgtt agttgagaag gtccacttat caacaaccgg cgctttgcca aacagccctt
    21001 cgtaggcatt caccagtgct ttaacggtga agtgatcttc ttccactttc caggtcggga
    21061 agtagcattc ggttgggtaa accaggccag tccaggacgg acggtcgtag ttgtacatag
    21121 aaacaaccgc gttagctttc tgtactgcag gcagggcgcg gatttcgtcc agcgcgcctt
    21181 cccaggtttc gccccaggtc agacggcggt caatagagac ggcgcagcta tctgctacag
    21241 cgcaacggct tggggatgtg aagaagattt cagaaacggt gagggtgcct ttgccgagga
    21301 attcgtcata acccagacgt tgggagagtt cttgtaattc gccaagaatc ggacccattt
    21361 tgaaaatggc gttgtcaccg cgttctggcg cagaaccgtg gcagctaaca ccctgaacat
    21421 caatacgaat ttccatacga ccgcgctgac cacggtatat ctggcagtcg gttggttcgg
    21481 tactgaccac aaattccggg cgaatgccgg attgttcaat aatgtactgc cagcacagac
    21541 cgtcgcagtc ttcttcctgc acagtaccgg taaccagcag ggtatattca tcttccagac
    21601 cgaggtcttt aatgatttta ccggcataaa ccatagatgc catgccgcct tcctggtcgg
    21661 aagtaccgcg accaccgatt agctcatcag tttccatgcc ttcgtacgga tcgaagtccc
    21721 agtttttgat gttgccaatg ccgacggtat cgatatgagc gtccattgcc accagacgcg
    21781 ggccgtggcc gatataaccg agaacgttgc ccatcgggtc gatttcaact ttatcgaagc
    21841 cgactttttc catctcttct ttaatacgat gtactacgcg tttttcgtcg cagctttcac
    21901 tgggaatagc aaccatgtcg cgcaggaagc gagtcatgtc cgcctggtaa tcttttgctt
    21961 tttcaagaat cagtttgaat ggaatattct tagccattat ttttctccag attttttact
    22021 ccccgttttg cagggagtag ttccaataga gtgattaagg tgctacagcg tgtttgcctt
    22081 cccagacaac ttcgcggtag tgcttcatgt cggtgtcgcc ttcagtgctg ataaccagca
    22141 ccacggcatc tttgttcagc gccagttttt ccatcaggct ttgacgttgc gggtgataat
    22201 gaaccgctgc gagaacgccc aaaccgacag cgccggattc accggagatg atgcgcggat
    22261 cgttgccgta cggattaccc agcacgcgca tacctaatgc ggcaacgctg tcctggcagg
    22321 agatgaattg ggtggcgcag ttacgtagga tttcccagcc cagcgggtta ggttcgccac
    22381 aggccaggcc tgccatgatg gtggccatat caccgccaac gttgacgatg tcgcctttga
    22441 cgccggagcg ataaatacag tcagctttgt caggttcaac aataatgctg tgcagatttt
    22501 gcgggctata gacgtcgacc agataaccca gcacaccacc ggccattgct ccgacaccgg
    22561 cttgcagcag aacgtgcgtc ggggttacgc ccatttcacg catttgctcg acggcttcat
    22621 ctgccagggt tgcgtagcct tgcatgatcc aggttgggat tttggtgtaa ccttcccatg
    22681 ccgtgtcctg taccacttcc cagccgtgct gctgcgcgtg ttgcatggtc aggcgaacgg
    22741 tatcgtcata gttcatatct gtgacgatgc actcggcacc gaggttcaga atggcgtcaa
    22801 cgcgttcctg agcagaacct ttcggcatgt aaatcaccgc attctgtccg agttgctgcg
    22861 ctgcccacgc cacaccgcgc ccgtggttgc cgtcggtggt ggtcgcgaaa gtcatttttt
    22921 cgccgatggc atttttcagg tgctcaaatg acagcgtttc gatatcaaga tgatattttt
    22981 cacacaataa ttgagcgata gcgtacgcac cgccgagcat tttgaaggcg ttcagaccga
    23041 atcgttttga ttcgtctttg acaagaattt tcttcacccc aaaaaggttt gcgagatcgt
    23101 ccagcgcaca aagcggtgtt gggcgataac cagctatttt ctggtggaac tggcgcgcca
    23161 gtttggcctg gctttgcgaa aagagcggtg atgtttcgcc gttgaaaaat ttgttatcgg
    23221 cgatatcaat cttcaatgag aaaacggaca tatcctatcc ttttggcctc tggaaataga
    23281 gggccgacca gctgatcggc ccgaggggtt atttcacgcg ttcttgcgct tctttcagca
    23341 gttgctcgag cagtgcacct ggtttggcgt atttacggga caggatcatc gcggcgatga
    23401 tataaggctt ccagctggct tctttgtagg tagcgatacg gtatttttcg aatacgcctt
    23461 cagtcacttc cccttctttg caggatacgc cgctgatatc agctggcagg cagtgcatgt
    23521 acagggcttc gccatcacgg gtcagttcca tcatctcttc agtacaatgc cagtctttgt
    23581 gttgcgcgtt ctgtgccaga cactgttttt ccagtgcttt taagccttcg tgatcgttag
    23641 cgcgcagcaa ttcggtacgc tgttccatca ctttgtaagg tgcccatgac ttcggataaa
    23701 cgatgtctgc atctttgaac gcttcttcca tgctggtgac ctgacggaag ctaccgccag
    23761 atgctttagc attgtttttc gccacttcaa ccacatccgg gatcaggtcg tagccttccg
    23821 gatgggccag ggtgacatcc ataccgaagc gagtcatcag accgatgatg ccttgtggta
    23881 cagagagcgg tttgccatag cttggagagt aggcccaggt catggcgatt tttttacctt
    23941 tcaggttttc cagtgaacca aagtgttcac gtaaccacgc gaggtcagcc attgactgag
    24001 tcgggtggtc aatatcgcat tgcaggttca ctaaagccgg acgctgtggc agtacaccct
    24061 gcttgtaacc gtcatcaagt gcagcgccaa cttcacgcat ataggcgttg cctgcgccca
    24121 gatacatatc gtcgcgaata ccaatagcgt cggcgcagaa ggagatcata ttggcggttt
    24181 cacgcacggt ttcgccgtga gcgatttgtg atttgccttc gtcgagatct tgttgtgcaa
    24241 ggccgagcag gttaagcgcg gaagcataag agaagcgggt acgggtggag ttgtcgcgga
    24301 atacggaaat acctaatcca ctattaaaga ctttggttga gatgttttca gcacgcagtg
    24361 cttttaatgc tgcggcaacg tccagtactt gtttcagttc atctggcgtc tgttcccacg
    24421 ttaacaaaaa atctttctcg tgaaggtgag aggtcagcga attgatatcc ttaatcagct
    24481 cattaacagt tttcatcata aagtcccggt agtggaatga caggcaaagt ggtttatttc
    24541 actgtgactt gccaaagtga ttggtgtttt cacagctata cctgggacta acaataagtg
    24601 tgccagaatt atccacgggg ctgcaaaaga ctaatttgac ggataatgtg tggggttgat
    24661 cacaaattga tgccagcttc cggttgtttg taaaatacga aaacgtttgg ctttttttat
    24721 cgcgttattt atttgctgct aagtatcaga aataagataa agggacaggc tatctctctt
    24781 cagtttgata aactcaccgc cgtaattctc atattgatat agaaatgtga tatctcttcc
    24841 ataatttcat tagaaaatga taaaaatctt atgtttttat caaagccaat ttcgcctgag
    24901 ttaatatcat catgatctgt gaaccatcaa cgtcttcaat gatcgacttt taagtaagtc
    24961 tggaaggtaa agctatggag cttgctacta cgcagtcagt attgatgcaa attcaaccga
    25021 caattcagcg ttttgccaga atgcttgcca gcgttttgca gcttgaggtt gagatcgttg
    25081 atgaaaactt gtgtcgcgtc gccggaacgg gcgcgtatgg gaagtttctt ggtcgccagt
    25141 tgagcggcaa ctcacgcctg ctccgccacg tcctggaaac gaaaactgaa aaagttgtga
    25201 cacagtctcg cttcgatccc ctttgcgaag gttgcgatag taaagaaaat tgccgtgaaa
    25261 aagcatttct gggtacgcct gtcattttac aggatcgttg tgttggggtg ataagtttga
    25321 ttgccgttac ccacgagcaa caagagcata tcagtgataa tttacgcgaa ttttctgatt
    25381 atgttcgcca tatatccacc atttttgttt cgaaacttct ggaggatcag gggccaggag
    25441 ataacatcag taaaatattc gcgaccatga tcgataatat ggatcagggc gtattagttg
    25501 ttgatgatga aagtcgggtt cagtttgtta atcagactgc cttaaaaaca cttggtgttg
    25561 tacaaaataa tattattggg aaacctatcc gtttcagacc attaacattt gagagtaatt
    25621 ttactcatgg acatatgcag catattgttt cgtgggacga taaaagtgaa ttaatcattg
    25681 gtcaattgca taacattcag ggccgacaat tatttttaat ggcatttcac caatcgcata
    25741 ccagtttttc tgtagcaaat gcacctgatg aaccacatat tgaacaattg gttggcgagt
    25801 gccgtgttat gcggcaatta aaacgactca ttagccgtat tgcacccagc ccatccagcg
    25861 ttatggtggt tggtgaaagc ggcacgggta aagaagtcgt cgcccgagca atccataagt
    25921 tgagcggaag acggaataaa ccctttattg ctatcaactg tgccgcgatt ccggagcagc
    25981 ttctggaaag cgaactgttc ggttatgtta aaggcgcatt tactggcgct tctgccaacg
    26041 gtaaaacagg gttgattcag gcggcgaata cgggcacgct gtttctcgat gaaataggtg
    26101 atatgccatt aatgttgcag gctaaattac tgcgcgctat tgaggcgcgt gaaattctgc
    26161 cgattggtgc cagtagccca atacaagtcg acattcgcat catttctgca actaatcaga
    26221 atttggccca gttcattgcc gaaggtaaat tccgcgaaga tctcttctac cgacttaatg
    26281 ttatcccgat aactctgcca ccgctgcgtg aacgtcagga agatattgaa ctattggtgc
    26341 attacttttt acatctgcat acccgtcgtc tgggatcggt ttatcctggc attgctcccg
    26401 atgtcgtcga aatattgcgt aagcatcgtt ggcccggaaa cctgcgcgag ttaagcaatt
    26461 tgatggaata tctggttaac gtagttcctt caggtgaagt tatcgacagc acgctattgc
    26521 cgccaaatct gctgaataat ggcacaacgg agcaaagtga tgtaacagag gtcagtgagg
    26581 cgcacctgtc actcgatgat gcgggcggca cggcgctgga ggagatggaa aagcaaataa
    26641 tccgcgaggc gctttcacgt cataacagca agaagcaagt tgctgatgaa ctgggcatcg
    26701 gcattgctac gctctatcgc aagattaaga aatatgagtt gttaaacaca taacctcagt
    26761 gaatccggcc tgaattcagg ccggatatcc ttttacttcg ttttctcgca atccagaact
    26821 gtatttacaa tcatctgata ccccgtgcag cgacaaagat ttcccgccag tccgcgacga
    26881 atttccgtaa tggttaatgg cttctcgcgt ggtttcgcca gcattgccgt ggtagccata
    26941 atcaggccag gcgtacaaaa cccgcactgc actgcgccgg atttcgcata agcctgctga
    27001 acatgagaaa gttttccgcc tttcgcttca ccttccagcg tgcggatctc ttttccttca
    27061 gcccaggcgg caaggtataa gcaactgtct attgctgtgc cgtcgaccaa caccgtacag
    27121 gcaccacatt cacccacgca gcacccttgt ttgacactta gcagtccttg ttcgcggagt
    27181 aattccgaga gcggcgtgcc tggtgcggcg tgaagctgaa aaggcatctc gttaatggtg
    27241 cattcgatgg taattgtttc gctgtgattc attgcaattt tccccccgcc gcggcgacgg
    27301 cttcgctaat cacttttttg gtcatcgtct ggatgagatg cagacgaaac tctttactgg
    27361 cccgccatga agaacgcggg gcgacatctt gcaggacaga ttcgctgata gcttccagcg
    27421 tttgcaggtt taatggcgca ttttgtgcag tctgttcggc atgttggcag cgaatcggcg
    27481 ttggcgcggc aacaccaaat gccaggcgta attcgctgaa attgccgtta tccagtcggc
    27541 aatgtgcggc gcagccaatc gttgaaatat ccattgcgtc gcgcatggca tatttaaaat
    27601 gcgcgctgcc cgcgtgttct ttcggctgtg gcggaaaatg aaaggcgacg aggatttcgt
    27661 catgctcaag agacactttg cccggcccgg tgtgaaagcc attaatcggg acgaaacgaa
    27721 caccgcgcgg ggagtggatc tccagtttcg cgtcataaat tagcgttggc gtggcagaat
    27781 ctgcgctggt ggcaccgttg caaatatttc caccgtaggt agcgacgtta cggatctgcg
    27841 gtccagcaat ggacgtggcc gcagcacata acgccgggag atgacgttga gttataggat
    27901 cttctattag ctgggtaaat gtcgttgcag agccgatacg tagcgagcca tcttccgcca
    27961 gcgtaattcc ccgcagctcc gccagattat gaatatcaac aatatggcga taacggtcat
    28021 tgtgatggtg gagctgaatc agtacgtcag tgccaccggc gagcagtttg gcctgcgggt
    28081 tgtcagccag caggttgatg gcatcggcaa gggttgctgc gcgatggtaa gaagcaaaat
    28141 caaacatgat gttatcctca aatcaatcct gccagatgga actcttcata taaccgtttt
    28201 ggcgtcagcg gcagtgtatt gattgcaaca ccggtagcca tcttcaccgc gttacgaata
    28261 gcagcggcaa caggaattat tggtggctca cccagtgact tatgtccgta tgcggattgc
    28321 ggctcattga tttcgacgaa cgcgctttcc agttgtggca gatccggcat ggtcggcatt
    28381 ttgtaatcca gcagattggg gttacggacc acgccgcttt tagcatcgat gatcatctct
    28441 tcaaatagcg cccagccaat gcccattccc attccgccgt gtacctgacc ttctgccagc
    28501 agtggattaa gaatatgccc tgaatcatga acgttgagga tgcggttgat gatgactttg
    28561 cacagcgcaa tatcgaccgt cagatcaaca aaggtacagc caaacgccgg tgggttagtg
    28621 gtggttttga tggagctttc agcagagagc tgcccgccgc gttcagggtg gtagaaagcg
    28681 tccatcgcca aatcttttaa cgacattaac ggctcttccg gtcgttcaac cagcacgata
    28741 tggcctttta tcagggtcag attcatcgct gactgatgta gcatgactgc ggcgtgagcg
    28801 atgattttct cttttaataa tagtgccgca ctgcgcagcg caggcgcggc aacatagctc
    28861 tggcgtgagg caaatgcgcc gggatcgaac ggcgtaacgt cggtatcttg agttgaaata
    28921 acgcgaacgt cgctgaccgg aacccccacg gtttctgcca ccatttgcga gaagacggtg
    28981 tcggcaccct gaccgatttc cgtcgcgccg ctttgcacgt tgatggttcc atcctgattc
    29041 atcagaaggc gcgcgcctgc tatttctacg ccgacaggcc aggtgttaga ggtgtagcta
    29101 aaacaggcga cgccaacgcc gcggcgcaaa ttgccttgct ggttctggca ttctgcacgg
    29161 cgtttttccc attcaaagat tttccggcct ttttcaagac actccggcaa ccctgcgctg
    29221 taaatacgtt tgcccgtgag cggattagca tctccttcgc gggcggcgtt gcgtaaacga
    29281 atttcaacag gatcaatacc taacgctgtc gcggcgtcat caagcataga ctcaacggca
    29341 aatacgactt gtggcgcgcc ataaccacgc atcgcaccag ccgaggggag gttggtatag
    29401 caggtctttg aactgtaagc gtaggcacaa cgaggataaa ggtaagcgac tttattcccc
    29461 cccgcagaag cgatggagtg cccgtgagat gcataagcgc cggtgttaga cagaacatcc
    29521 agactataac ctttcaatgt tccgtcgcgg ttcacgccca tttgcccgtc aatggtaaaa
    29581 gcgtggcggg tacgggttgc gaggaaacac tcttcacggc taagggaaac tttcaccgga
    29641 atgccgccaa gcttgctggt caggaatgcc gccattggct cttccagtac atcctgttta
    29701 ttaccaaaac cgccaccgac aaatggtttg atgactcgta cgcatgacca gggaatatcc
    29761 agcgcctgac caaccacgcg gcgaacaatg tgcgggatct gggtgctgga aacgatggta
    29821 attcgcgagt catcctccat ccacgccagc gatgttacgc tttccatgtg acaatgttga
    29881 ataacggggg tctgatagtg cccctgtacc tggtagtcgg cggcatcgat tgtttgttgg
    29941 acattacccg tcgacatcgt gctttgtttc agtaaattgc caccgttatg gattggtgca
    30001 gcgtcttctg ccagcgccgc ttctggcgtg gtgataacgg gtaattcttg ccactcaatg
    30061 ctgaccaatt gcgccgcttt ttctgccgtg agttcatcgc gggccacgac gatggcaacg
    30121 gcgtcaccat gatgacgaac atggcgagtt agcagtgcgc gatcggcggt atcgcgcttg
    30181 ttttcgtcaa gtgtccaggc atgcccagct gtagcgaatg gaatatcagg cacatcttcc
    30241 caggtaaaaa tcgccagtac gcccggcaaa cttctggctt gttcatcatt aatacttacg
    30301 gcataaccat gtgcgatagg gctacgtaca tatttcgcat aacacatgcc cgccataaca
    30361 taatcgtcag tatatcgtgc ccgcccggtg accttagcaa tggcatcgac gcgcatgcat
    30421 gattcacccg tagcggttgc ttcccgcgct tccatagaaa tcccctcgat ttgaacattt
    30481 ggttcttatg gcaaagattt agtctaagca ggcaagattt acgccagaaa cgacgataag
    30541 cgttagggga ggtaggaagt gtgatgacgt taaaaaaaca cagatatgat acgaaacagg
    30601 actctgaata ggggcagtga tacgtatcaa tatgagtggc gataaaatca atgtgataaa
    30661 ttgggattat tacgcatcag gatgggaaat agggtaaaaa gtcaggaagt tcgatacctc
    30721 tacagcgaat attttgctga tgatacttcc ctttgccaaa tgaaattaac ctctttctct
    30781 attaccacgt ttttccagaa gcaagagatt gggtatcaag aggctggctg ctatgataag
    30841 gcgtcttgtt ttttaagcga ggaaagattt tgagtgcggg acgcctgaat aaaaaatctc
    30901 tgggtatcgt gatgttgtta tcggttggac tgcttttggc gggctgttcg ggtagcaaat
    30961 catccgatac aggaacgtat tccggctccg tttacaccgt gaaacggggg gatacgctat
    31021 atcgtatttc gcgcaccacg ggaaccagcg taaaagaact ggcgcgactg aacggcattt
    31081 ccccccctta caccattgaa gttggtcaga aactaaaact gggtggggcg aaaagtagca
    31141 gtagtacacg taaatcaacc gccaaatcaa cgaccaaaac cgcatcggtt acaccgtcat
    31201 cagcggtacc gaaatcttcc tggccgccag tagggcaacg ttgttggtta tggccaacga
    31261 cagggaaagt tatcatgccg tattcgacag cagatggcgg caataaaggg attgatatct
    31321 cagctccacg gggtacacct atttacgccg cgggtgcagg aaaggtggtg tatgtgggca
    31381 accagctgcg tggctacggt aatctcatca tgattaaaca cagtgaagat tacattacgg
    31441 cttacgccca taatgacacg atgctggtaa ataatgggca aagcgtgaag gctgggcaaa
    31501 aaatcgccac tatggggagc acggatgcgg catctgttcg cctgcatttc cagattcgtt
    31561 accgtgcaac ggcaattgat ccgctacgtt acttgccgcc gcagggcagc aagccaaaat
    31621 gctgatggcg aattaatcag cagtcagcag cgcggcactt gctaaggaga gcgtaaggtt
    31681 tataatgcct tacgcatctc gaagcgggcg tagttcaatg gtagaacgag agcttcccaa
    31741 gctctatacg agggttcgat tcccttcgcc cgctccatga cacttcttaa agtctactaa
    31801 cttactgaat cctaagggat acggcttaac gccttccgat agttttactc actgtaacca
    31861 acactgtgac taactttgtt gaagtagtga gcagacctaa ggtctcagta catgctcaag
    31921 tcaagaacct acctttatca gcgtaatggt gtcttttaca tccgtcttag gatgaagacc
    31981 actagtcgcc tgaccgcttc gcttccttct cacaaccgtt ataaactagc gtcagtatct
    32041 ttacggacca aggatagacg taccgctatg gctcactcac ggcacatcaa gtcagcactt
    32101 aaagcaatcc atgcagataa ccctaacgcc tcttatgagg agctacggga gcacctgaag
    32161 accattgtcg agtgggaact tagtgtcagc cgtgatgacc ttaacgaccc ggagtcctac
    32221 cagctttacg ttgaccagta cgacgacatc aagtccaacc ttcgggaagc tgtagcgact
    32281 gagcgtctga ctgtagacca gcatcactat atcaatgacg ttatcggtgt acttaaagcc
    32341 tgtcaggata gactcaaggg cgataactct ggcctgttgt cttaccttga gcctgagact
    32401 ggcagtctaa gaccgtccgt ctccctatct gtatcatcgg agcctgaagt ccctgaacct
    32461 ctcgtgactc tggaacgagt aactaaagca ctgaccctcg cgtctctcat tgagcagtac
    32521 gagcaggaga acgcccagaa ctggaagcca gcgaccctaa gcgaaaaccg agcgtcacac
    32581 tctacgctaa tcgagatatt cgactatctg gatattcagg atgtcggcaa ggcgacccgt
    32641 gcagatatgc ttagggtccg tgaagtcctc cagcagctac cgaagaaccg caagcaacgc
    32701 tttaaggaca taccgctgtc tgacctgctg aaccgggagt ctaagactga ctgtttggat
    32761 gtcgttacca tcaacaataa ataccttatc aagatggctg ctgtgtttaa gtgggcggta
    32821 cgcaacgacc tgatagctaa gaacctgaca gaaggtcttg agctgaaagt cccgcagcgt
    32881 aaagcctccg acgctcgtga tgcgttcagt cctgagcagg taaggcaact actggtcgca
    32941 gctaaagcgt actcgcagaa gacctcaggt aagccatacc attattacgt caccgctctg
    33001 gctgcaatca ctggagcaag acttaacgag gtggcccaac ttcaggttaa agatgtcagg
    33061 accactgagg ctgggaccgt ttttatccat atcaacgaag acgatagcag cctgccgggt
    33121 aagagtatca agaacgccca cagtgaccgc tgtgtcccgt tggtagatgg tgcttatggt
    33181 tttgtattgg ctgactttat gtcactcgtg gaagaccgta gaaagactgc gggtgataat
    33241 gctatggtat tcgatggcct caagctgatg aagaatggct acggtgagca ggtgagcaaa
    33301 tggtttaacc ggaccttgtt accaaaagtt ctcgctgacc gtagcggctt agcgtttcac
    33361 tcgtttagac atacagttgc gacccagtta aaacaacatg gggtcgagct agcgtatgct
    33421 caggcgatta tgggtcatag ctcagggtct ataacttacg accgttacgc taaagaggtc
    33481 gaggtggata gattggttaa tgtgatggca ggtgtttata aggagactgg attaaatggc
    33541 tgagtattat ccggcggtgt ttgaagcaga ggcttttaac tgtcctcact gtggtgtata
    33601 tgcccgtcag ttctggc
//
LOCUS       DAPOAV010000048        31493 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.048, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000048 DAPOAV010000000
VERSION     DAPOAV010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31493
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.048"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            9..911
                     /locus_tag="RN951_002539"
     CDS             9..911
                     /locus_tag="RN951_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX2527521.1"
                     /translation="MANLYDLKKFDLNLLVIFECIYQHLSISKAAESLYITPSALSQS
                     LQRLRAQFNDPLFIRSGKGIAPTTTGLNLHHHLEKNLRGLEQTINIVNKSELKKNFII
                     YGPQLISCSNNSMLIRCLRQDSSVEIECHDILMSAENAEELLVHRKADLVITQMPVIS
                     RSVICMPLHTIRNTLICSNRHPRITDNSTYEQIMAEEFTQLISKSAGVDDIQMEIDER
                     FMNRKISFRGSSLLTIINSIAVTDLLGIVPYELYNSYRDFLNLKEIKLEHPLPSIKLY
                     ISYNKSSLNNLVFSRFIDRLNESF"
     gene            1058..2278
                     /locus_tag="RN951_002540"
     CDS             1058..2278
                     /locus_tag="RN951_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HDX2527522.1"
                     /translation="MSIYKIPLPLNILEAARERITWTLNTLPRVCVSFSGGKDSGLML
                     HLTAELARQMGKKICVLFIDWEAQFSCTINYVQSLRELYTDVIEEFYWVALPLTTQNS
                     LSQYQPEWQCWEPDVEWVRQPPQDAITDPDFFSFYQPGMTFEQFVREFAEWFSQKRPA
                     AMMIGIRADESYNRFVAIASLNKQRFADDKPWTTAAPGGHSWYIYPIYDWKVADIWTW
                     YANHQSLCNPLYNLMYQAGVPLRHMRICEPFGPEQRQGLWLYHVIEPDRWAAMCARVS
                     GVKSGGIYAGHDNHFYGHRKILKPEHLDWQEYALLLLNSMPEKTAEHYRNKIAIYLHW
                     YQKKGIEVPQTQQGDIGAKDIPSWRRICKVLLNNDYWCRALSFSPTKSKNYQRYNERI
                     KGKRQEWGILCNND"
     gene            2251..2880
                     /locus_tag="RN951_002541"
     CDS             2251..2880
                     /locus_tag="RN951_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HDX2527523.1"
                     /translation="MGDTMQQRLTQDLTQFLASLPEDDRIKAINEIRMAIHQVSPFRE
                     EPVDCVLWVKNSQLMPNDYNPNNVAPPEKKLLQKSIEIDGFTQPIVVTHTDKNAMEIV
                     DGFHRHEIGKGSSSLKLRLKGYLPVTCLEGTRNQRIAATIRHNRARGRHQITAMSEIV
                     RELSQLGWDDNKIGKELGMDSDEVLRLKQINGLQELFADRQYSRAWTVK"
     gene            complement(2881..4041)
                     /gene="ybdL"
                     /locus_tag="RN951_002542"
     CDS             complement(2881..4041)
                     /gene="ybdL"
                     /locus_tag="RN951_002542"
                     /EC_number="2.6.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine-oxo-acid transaminase"
                     /protein_id="HDX2527524.1"
                     /translation="MTNNPLIPQSKLPQLGTTIFTQMSALAQQHQAINLSQGFPDFDG
                     PRYLQERLAHHVAQGANQYAPMTGVQALREAIAQKTERLYGYQPDADSDITVTAGATE
                     ALYAAITALVRNGDEVICFDPSYDSYAPAIALSGGIVKRMALQPPHFRVDWQEFAALL
                     SERTRLVILNTPHNPSATVWQQADFAALWQAIAGHEIFVISDEVYEHINFSQQGHASV
                     LAHPQLRERAVAVSSFGKTYHMTGWKVGYCVAPAPISAEIRKVHQYLTFSVNTPAQLA
                     LADMLRAEPEHYLALPDFYRQKRDILVNALNESRLEILPCEGTYFLLVDYSAVSTLDD
                     VEFCQWLTQEHGVAAIPLSVFCADPFPHKLIRLCFAKKESTLLAAAERLRQL"
     gene            4150..5238
                     /gene="hcxA"
                     /locus_tag="RN951_002543"
     CDS             4150..5238
                     /gene="hcxA"
                     /locus_tag="RN951_002543"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxycarboxylate dehydrogenase HcxA"
                     /protein_id="HDX2527525.1"
                     /translation="MPHNPIRVVVGPANYFSHPGSFNHLHDFFTDEQLSRAVWIYGKR
                     AIAAAQTKLPPAFGLPGAKHILFRGHCSESDVQQLAAESGDDRSVVIGVGGGALLDTA
                     KALARRLGLPFVAVPTIAATCAAWTPLSVWYNDAGQALHYEIFDDANFMVLVEPEIIL
                     NAPQQYLLAGIGDTLAKWYEAVVLAPQPETLPLTVRLGINNAQAIRDVLLNSSEQALS
                     DQQNQQLTQSFCDVVDAIIAGGGMVGGLGDRFTRVAAAHAVHNGLTVLPQTEKFLHGT
                     KVAYGILVQSALLGQDDVLAQLTGAYQRFHLPTTLAELEVDINNQAEIDKVIAHTLRP
                     VESIHYLPVTLTPDTLRAAFKKVESFKA"
     gene            complement(5248..5445)
                     /locus_tag="RN951_002544"
     CDS             complement(5248..5445)
                     /locus_tag="RN951_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HDX2527526.1"
                     /translation="MFDSLAKAGKYLGQAAKLMIGMPDYDNYVEHMRVNHPDQTPMTY
                     EEFFRERQDARYGGKGGARCC"
     gene            complement(5628..7733)
                     /gene="cstA"
                     /locus_tag="RN951_002545"
     CDS             complement(5628..7733)
                     /gene="cstA"
                     /locus_tag="RN951_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein CstA"
                     /protein_id="HDX2527527.1"
                     /translation="MNKSGKYLVWTVLSVMGAFALGYIALNRGEQINALWIVVASVCI
                     YLIAYRFYGLYIAKNVLAVDPTRMTPAVRHNDGLDYVPTDKKVLFGHHFAAIAGAGPL
                     VGPVLAAQMGYLPGMIWLLAGVVLAGAVQDFMVLFVSTRRDGRSLGELVKEEMGPTAG
                     VIALVACFMIMVIILAVLAMIVVKALTHSPWGTYTVAFTIPLALFMGIYLRYLRPGRI
                     GEVSVIGLVFLIFAIISGGWVAESPTWAPYFDFTGVQLTWMLVGYGFVAAVLPVWLLL
                     APRDYLSTFLKIGTIVGLAVGILIMRPTLTMPALTKFVDGTGPVWTGNLFPFLFITIA
                     CGAVSGFHALISSGTTPKMLANEGQACFIGYGGMLMESFVAIMALVSACIIDPGVYFA
                     MNSPMAVLAPAGTADVVASAAQVVSSWGFSITPDTLNQIASEVGEQSIISRAGGAPTL
                     AVGMAYILHGALGGMMDVAFWYHFAILFEALFILTAVDAGTRAARFMLQDLLGVVSPG
                     LKRTDSLPANLLATALCVLAWGYFLHQGVVDPLGGINTLWPLFGIANQMLAGMALMLC
                     AVVLFKMKRQRYAWVALVPTAWLLICTLTAGWQKAFSPDAKVGFLAIANKFQAMIDSG
                     NIPSQYTESQLAQLVFNNRLDAGLTIFFMVVVVVLALFSIKTALAALKDPKPTAKETP
                     YEPMPENVEEIVAQAKGAH"
     gene            complement(7914..8327)
                     /gene="entH"
                     /locus_tag="RN951_002546"
     CDS             complement(7914..8327)
                     /gene="entH"
                     /locus_tag="RN951_002546"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proofreading thioesterase EntH"
                     /protein_id="HDX2527528.1"
                     /translation="MIWKRHLTLDELNATSDNTMVAHLGIVYTRLGDDVLEAEMPVDT
                     RTHQPFGLLHGGASAALAETLGSMAGFMMTRDGQCVVGTELNATHHRPVSEGKVRGVC
                     QPLHLGRQNQSWEIVVFDEQGRRCCTCRLGTAVLG"
     gene            complement(8330..9076)
                     /gene="entA"
                     /locus_tag="RN951_002547"
     CDS             complement(8330..9076)
                     /gene="entA"
                     /locus_tag="RN951_002547"
                     /EC_number="1.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
                     EntA"
                     /protein_id="HDX2527529.1"
                     /translation="MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTQEQY
                     PFATEVMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAV
                     NVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL
                     ELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEI
                     ANTILFLASDLASHITLQDIVVDGGSTLGA"
     gene            complement(9076..9933)
                     /gene="entB"
                     /locus_tag="RN951_002548"
     CDS             complement(9076..9933)
                     /gene="entB"
                     /locus_tag="RN951_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin biosynthesis bifunctional
                     isochorismatase/aryl carrier protein EntB"
                     /protein_id="HDX2527530.1"
                     /translation="MAIPKLQAYALPESHDIPQNKVDWAFEPQRAALLIHDMQDYFVS
                     FWGENCPMMEQVIANIAALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRS
                     PEQQKVVDRLTPDADDTVLVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTT
                     ATDAFMRDIKPFMVADALADFSRDEHLMSLKYVAGRSGRVVMTEELLPAPIPASKAAL
                     REVILPLLDESDEPFDDDNLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAW
                     WKLLSREVK"
     gene            complement(9947..11557)
                     /gene="entE"
                     /locus_tag="RN951_002549"
     CDS             complement(9947..11557)
                     /gene="entE"
                     /locus_tag="RN951_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2,3-dihydroxybenzoyl)adenylate synthase EntE"
                     /protein_id="HDX2527531.1"
                     /translation="MSIPFTRWPEEFARRYREKGYWQDLPLTDILTRHAASDSIAVID
                     GERQLSYRELNQAADNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVL
                     ALFSHQRSELNAYASQIEPALLIADRQHALFSGDDFLNTFVTEHSSIRVVQLLNDSGE
                     HNLQDAINHPAEDFTATPSPADEVAYFQLSGGTTGTPKLIPRTHNDYYYSVRRSVEIC
                     QFTQQTRYLCAIPAAHNYAMSSPGSLGVFLAGGTVVLAADPSATLCFPLIEKHQVNVT
                     ALVPPAVSLWLQALIEGESRAQLASLKLLQVGGARLSATLAARIPAEIGCQLQQVFGM
                     AEGLVNYTRLDDSAEKIIHTQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFR
                     GYYKSPQHNASAFDANGFYCSGDLISIDPEGYITVQGREKDQINRGGEKIAAEEIENL
                     LLRHPAVIYAALVSMEDELMGEKSCAYLVVKEPLRAVQVRRFLREQGIAEFKLPDRVE
                     CVDSLPLTAVGKVDKKQLRQWLASRASA"
     gene            complement(11567..12742)
                     /gene="entC"
                     /locus_tag="RN951_002550"
     CDS             complement(11567..12742)
                     /gene="entC"
                     /locus_tag="RN951_002550"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase EntC"
                     /protein_id="HDX2527532.1"
                     /translation="MDTSLAEEVQQTMATLAPNRFFFMSPYRSFTTSGCFARFDEPAV
                     NGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEK
                     QASARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDA
                     AIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARR
                     QPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWH
                     LATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWC
                     DSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH"
     gene            13117..14073
                     /gene="fepB"
                     /locus_tag="RN951_002551"
     CDS             13117..14073
                     /gene="fepB"
                     /locus_tag="RN951_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe2+-enterobactin ABC transporter
                     substrate-binding protein"
                     /protein_id="HDX2527533.1"
                     /translation="MRLAPLYRNALLLTGLLLSGIAAVQAADWPRQITDSRGTHTLES
                     QPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQRLY
                     IGEPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKSWQSLLTQLG
                     EITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLWTPESAQGQM
                     LEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGESLFLFAGDQKDADAIY
                     ANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQVLDRLKALF"
     gene            complement(14077..15327)
                     /gene="entS"
                     /locus_tag="RN951_002552"
     CDS             complement(14077..15327)
                     /gene="entS"
                     /locus_tag="RN951_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin transporter EntS"
                     /protein_id="HDX2527534.1"
                     /translation="MNKQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQI
                     QMMTHSTWQVGLSVTLTGGAMFVGLMVGGVLADRYERKKVILLARGTCGIGFIGLCLN
                     ALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSV
                     ISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPPPPQPREHPLKSLLAGFR
                     FLLASPLVGGIALLGGLLTMASAVRVLYPALADNWQMSAAQIGFLYAAIPLGAAIGAL
                     TSGKLAHSARPGLLMLLSTLGSFLAIGLFGLMPMWILGVVCLALFGWLSAVSSLLQYT
                     MLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGGLGAMMTPVASASASGFGLLIIGV
                     LLLLVLVELRHFRQTPPQVTASDS"
     gene            15438..16442
                     /gene="fepD"
                     /locus_tag="RN951_002553"
     CDS             15438..16442
                     /gene="fepD"
                     /locus_tag="RN951_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-siderophore ABC transporter permease"
                     /protein_id="HDX2527535.1"
                     /translation="MSGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEAF
                     SGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGAS
                     FAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAA
                     VLEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALN
                     SLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAIVGPIAFIGLMMPHMARWLVGA
                     DHRWSLPVTLLATPALLLFADIIGRVIVPGELRVSVVSAFIGAPVLIFLVRRKTRGGA
                     "
     gene            16439..17431
                     /gene="fepG"
                     /locus_tag="RN951_002554"
     CDS             16439..17431
                     /gene="fepG"
                     /locus_tag="RN951_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter permease"
                     /protein_id="HDX2527536.1"
                     /translation="MIYVSRRLLITCLLLVSACVVAGIWGLRSGAVTLETSQVFAALM
                     GDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWS
                     GVLVAMVLFGQDLTAIALSAMVGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA
                     FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLE
                     MGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTARW
                     GLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESRKK"
     gene            17428..18243
                     /gene="fepC"
                     /locus_tag="RN951_002555"
     CDS             17428..18243
                     /gene="fepC"
                     /locus_tag="RN951_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter ATP-binding
                     protein"
                     /protein_id="HDX2527537.1"
                     /translation="MTESVARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGC
                     GKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQNATTPGDITVQELV
                     ARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQ
                     ETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALR
                     EGKIVAQGAPKEIVTAELIERIYGLRCMIIDDPVAGTPLVVPLGRTAPSTANS"
     gene            complement(18240..19373)
                     /gene="fepE"
                     /locus_tag="RN951_002556"
     CDS             complement(18240..19373)
                     /gene="fepE"
                     /locus_tag="RN951_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS O-antigen length regulator"
                     /protein_id="HDX2527538.1"
                     /translation="MSSLNIKQGSDAHFPDYPLASSSNNEIDLLNLISVLWRAKKTVM
                     AVVFAFACAGLLISFILPQKWTSAAVVTPPEPVQWQELEKSFTKLRVLDLDIKIDRTE
                     AFNLFIKKFQSVSLLEEYLRSSPYVMDQLKEAKIDELDLHRAIVALSEKMKAVDDNAS
                     KKKDEPSLYTSWTLSFTAPTSEEAQTVLSGYIDYISTLVVKESLENVRNKLEIKTQFE
                     KEKLAQDRIKTKNQLDANIQRLNYSLDIANAAGIKKPVYSNGQAVKDDPDFSISLGAD
                     GIERKLEIEKAVTDVAELNGELRNRQYLVEQLTKAHVNDVNFTPFKYQLSPSLPVKKD
                     GPGKAIIVILSALIGGMVACGGVLLRYAMASRKQDAMMADHLV"
     gene            complement(19589..23470)
                     /gene="entF"
                     /locus_tag="RN951_002557"
     CDS             complement(19589..23470)
                     /gene="entF"
                     /locus_tag="RN951_002557"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin non-ribosomal peptide synthetase
                     EntF"
                     /protein_id="HDX2527539.1"
                     /translation="MSQHLPLVAAQPGIWMAEKLSELPSAWSVAHYVELTGEVDSPLL
                     ARAVVAGLAQADTLRMRFTEDNGEVWQWVDDALTFELPEIIDLRTNIDPHGTAQALMQ
                     ADLQQDLRVDSGKPLVFHQLIQVADNRWYWYQRYHHLLVDGFSFPAITRQIANIYCTW
                     LRGEPTPASPFTPFADVVEEYQQYRESEAWQRDAAFWAEQRRQLPPPASLSPAPLPGR
                     SASADILRLKLEFTDGEFRQLATQLSGVQRTDLALALAALWLGRLCNRMDYAAGFIFM
                     RRLGSAALTATGPVLNVLPLGIHIAAQETLPELATRLAAQLKKMRRHQRYDAEQIVRD
                     SGRAAGDEPLFGPVLNIKVFDYQLDIPDVQAQTHTLATGPVNDLELALFPDVHGDLSI
                     EILANKQRYDEPTLIQHAERLKMLIAQFAADPALLCGDVDIMLPGEYAQLAQLNATQV
                     EIPETTLSALVAEQAAKTPDAPALADARYLFSYREMREQVVALANLLRERGVKPGDSV
                     AVALPRSVFLTLALHAIVEAGAAWLPLDTGYPDDRLKMMLEDARPSLLITTDDQLPRF
                     SDVPNLTSLCYNAPLTPQGSAPLQLSQPHHTAYIIFTSGSTGRPKGVMVGQTAIVNRL
                     LWMQNHYPLTGEDVVAQKTPCSFDVSVWEFFWPFIAGAKLVMAEPEAHRDPLAMQQFF
                     AEYGVTTTHFVPSMLAAFVASLTPQTARQSCATLKQVFCSGEALPADLCREWQQLTGA
                     PLHNLYGPTEAAVDVSWYPAFGEELAQVRGSSVPIGYPVWNTGLRILDAMMHPVPPGV
                     AGDLYLTGIQLAQGYLGRPDLTASRFIADPFAPGERMYRTGDVARWLDNGAVEYLGRS
                     DDQLKIRGQRIELGEIDRVMQALPDVEQAVTHACVINQAAATGGDARQLVGYLVSQSG
                     LPLDTSALQAQLRETLPPHMVPVVLLQLPQLPLSANGKLDRKALPLPELKAQAPGRAP
                     KAGSETIIAAAFSSLLGCDVQDADADFFALGGHSLLAMKLAAQLSRQVARQVTPGQVM
                     VASTVAKLATIIDAEEDSTRRMGFETILPLREGNGPTLFCFHPASGFAWQFSVLSRYL
                     DPQWSIIGIQSPRPNGPMQTAANLDEVCEAHLATLLEQQPHGPYYLLGYSLGGTLAQG
                     IAARLRARGEQVAFLGLLDTWPPETQNWQEKEANGLDPEVLAEINREREAFLAAQQGS
                     TSTELFTTIEGNYADAVRLLTTAHSVPFDGKATLFVAERTLQEGMSPERAWSPWIAEL
                     DIYRQDCAHVDIISPGTFEKIGPIIRATLNR"
     gene            complement(23467..23685)
                     /gene="ybdZ"
                     /locus_tag="RN951_002558"
     CDS             complement(23467..23685)
                     /gene="ybdZ"
                     /locus_tag="RN951_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin biosynthesis protein YbdZ"
                     /protein_id="HDX2527540.1"
                     /translation="MAFSNPFDDPQGAFYILRNAQGQFSLWPQQCVLPAGWDIVCQPQ
                     SQASCQQWLEAHWRTLTPTNFTQLQEAQ"
     gene            complement(23688..24890)
                     /gene="fes"
                     /locus_tag="RN951_002559"
     CDS             complement(23688..24890)
                     /gene="fes"
                     /locus_tag="RN951_002559"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415117.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterochelin esterase"
                     /protein_id="HDX2527541.1"
                     /translation="MTALKVGSESWWQSKHGPEWQRLNDEMFEVTFWWRDPQGSEEYS
                     TIKRVWVYITGVTDHHQNSQPQSMQRIAGTNVWQWTTQLNANWRGSYCFIPTERDDIF
                     SVPSPDRLELREGWRKLLPQAIADPLNLQSWKGGRGHAVSALEMPQAPLQPGWDCPQA
                     PEIPAKEIIWKSERLKKSRRVWIFTTGDATAEERPLAVLLDGEFWAQSMPVWPVLTSL
                     THRQQLPPAVYVLIDAIDTTHRAHELPCNADFWLAVQQELLPLVKAIAPFSDRADRTV
                     VAGQSFGGLSALYAGLHWPERFGCVLSQSGSYWWPHRGGQQEGVLLEKLKAGEVSAEG
                     LRIVLEAGIREPMIMRANQALYAQLHPIKESIFWRQVDGGHDALCWRGGLMQGLIDLW
                     QPLFHDRS"
     gene            24928..25128
                     /locus_tag="RN951_002560"
     CDS             24928..25128
                     /locus_tag="RN951_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527542.1"
                     /translation="MQKYIDNIIDNYLHLQYRNGAPWEARTLINQLHCVSFRIKGFRG
                     SGMRRVDDDHARQLQFVAKMQE"
     gene            25133..27373
                     /gene="fepA"
                     /locus_tag="RN951_002561"
     CDS             25133..27373
                     /gene="fepA"
                     /locus_tag="RN951_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore enterobactin receptor FepA"
                     /protein_id="HDX2527543.1"
                     /translation="MNKKIHSLALLVNLGIYGVAQAQEPTDTPVSHDDTIVVTAAEQN
                     LQAPGVSTITADEIRKNPVARDVSEIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPE
                     NTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAA
                     GGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLD
                     KTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYS
                     RQGNLYAGDTQNTNSDSYTRSKYGDETNRLYRQNYALTWNGGWDNGVTTSNWVQYEHT
                     RNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWN
                     QQRMKDLSSNTQALTGTNTGGAIDGVSTTDRSPYSKAEIFSLFAENNMELTDSTIVTP
                     GLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQG
                     CYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVG
                     QNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSII
                     PEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLS
                     ATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYM
                     SVNTHF"
     gene            27548..28168
                     /gene="entD"
                     /locus_tag="RN951_002562"
     CDS             27548..28168
                     /gene="entD"
                     /locus_tag="RN951_002562"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415115.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin synthase subunit EntD"
                     /protein_id="HDX2527544.1"
                     /translation="MKTTHTSLPFAGHTLHFVEFDPANFCEQDLLWLPHYAQLQHAGR
                     KRKTEHLAGRIAAVYALREYGYKCVPAIGELRQPVWPAEVYGSISHCGTTALAVVSRQ
                     PIGIDIEEIFSVQTARELTDNIITPAEHERLADCGLAFSLALTLAFSAKESAFKASEI
                     QTDAGFLDYQIISWNKQQVIIHRENEMFAVHWQIKEKIVITLCQHD"
     gene            complement(28450..29562)
                     /locus_tag="RN951_002563"
     CDS             complement(28450..29562)
                     /locus_tag="RN951_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4-like element IS421 family transposase"
                     /protein_id="HDX2527545.1"
                     /translation="MNYSHDNWSAILAHIGKPEELDTSARNAGALTRRREIRDAATLL
                     RLGLAYGPGGMSLREVTAWAQLHDVATLSDVALLKRLRNAADWFGILAAQTLAVRAAV
                     TGCTSGKRLRLVDGTAISAPGGGSAEWRLHMGYDPHTCQFTDFELTDSRDAERLDRFA
                     QTADEIRIADRGFGSRPECIRSLAFGEADYIVRVHWRGLRWLTAEGMRFDMMGFLRGL
                     DCGKNGETTVMIGNSGNKKAGAPFPARLIAVSLPPEKALISKTRLLSENRRKGRVVQA
                     ETLEAAGHVLLLTSLPEDEYSAEQVADCYRLRWQIELAFKRLKSLLHLDALRAKEPEL
                     AKAWIFANLLAAFLIDDIIQPSLDFPPRSAGSEKKN"
     gene            complement(29639..29791)
                     /gene="hokE"
                     /locus_tag="RN951_002564"
     CDS             complement(29639..29791)
                     /gene="hokE"
                     /locus_tag="RN951_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokE"
                     /protein_id="HDX2527546.1"
                     /translation="MLTKYALAAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVL
                     AYEPKK"
     gene            30244..31362
                     /locus_tag="RN951_002565"
     CDS             30244..31362
                     /locus_tag="RN951_002565"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HDX2527547.1"
                     /translation="MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNK
                     ITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAATDHHLEICGGGTHPF
                     QKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPH
                     FIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMID
                     SIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKD
                     YLLYKFNRFQACRYGLEGVITDPHTGDRRPLTEDTLRLLEKIAPSAHKIGASSAIEAL
                     HRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGD"
     gene            31428..>31493
                     /locus_tag="RN951_002566"
     CDS             31428..>31493
                     /locus_tag="RN951_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1158 family protein"
                     /protein_id="HDX2527548.1"
                     /translation="MKHPLETLTTAAGILLMAFLSC"
BASE COUNT         7569 a         8706 c         8049 g         7169 t
ORIGIN      
        1 agtagtgtat ggccaatctc tacgacttga aaaagttcga cttaaatctt cttgtcatat
       61 ttgagtgtat ttaccagcat ttaagcatta gcaaagctgc tgaatcacta tatatcaccc
      121 catcagccct gagccagtcg ttacaacgct tacgtgcgca atttaatgac cctttattca
      181 ttcgctcagg aaaaggtatc gcgccgacga caacagggtt aaatctgcat caccatcttg
      241 agaaaaatct cagaggcctt gaacaaacaa ttaatatagt caataagtcc gaactaaaga
      301 aaaactttat tatctacggc cctcagctca tttcttgctc taataatagt atgctgatcc
      361 gctgcctacg gcaagattcc tctgtcgaga ttgagtgcca tgatatcctc atgtcagcag
      421 agaatgctga agaactgttg gttcaccgca aagccgatct ggtgatcacc caaatgccag
      481 tgatcagccg ttccgtcatt tgcatgccat tgcatacgat tcgcaatact ctaatttgta
      541 gtaataggca tccacgaatt actgacaata gcacttatga acaaattatg gcagaagagt
      601 tcacccaatt aatatctaaa tcagcagggg ttgatgatat tcaaatggaa atagacgaga
      661 gatttatgaa tcgcaaaatc tcatttcgtg gttcctcttt gctgacaatc attaatagca
      721 ttgcagttac agatttactg ggaatagtcc cctatgaact ttataattcc taccgtgact
      781 ttcttaactt aaaagagata aaactagaac atccgttacc ttcaataaag ctttacattt
      841 cctataataa atcttcttta aataatttgg tgttctcccg atttattgac cgtctaaatg
      901 agagtttttg atatataact acagacagct actataactt tcatctattt attcacagcg
      961 cgaatgaaaa ataaaacact ctgctttaca gtgtttactt tataattaac agacttatct
     1021 cactgatcac cctgtaacgt tcagagagcg tcttcagatg tctatttata aaattcctct
     1081 tccgctcaat attctggaag ctgcacgaga gcgtattacc tggacactca acaccctacc
     1141 ccgcgtttgt gtctcatttt ctggcggcaa agactctggt ttaatgctgc atctgacagc
     1201 cgaacttgcc cgacaaatgg gcaaaaaaat ctgcgttttg tttatcgact gggaggcgca
     1261 attctcttgc accattaact atgttcagtc cctgcgcgag ttgtacaccg atgtcatcga
     1321 agagttttac tgggttgcgc tcccgcttac gacgcaaaat tccctttcac aataccaacc
     1381 cgaatggcag tgctgggaac ctgatgtcga atgggtacgt caacctcccc aagatgcgat
     1441 aaccgaccct gactttttct ccttttacca gccaggcatg accttcgaac aatttgtacg
     1501 tgagtttgcc gaatggtttt cacaaaaacg tccggcggcg atgatgatcg gcatccgtgc
     1561 ggatgagtcc tacaaccgtt ttgtcgccat cgccagttta aataaacaac gttttgccga
     1621 cgataaaccc tggactacgg ccgcaccagg cggtcatagc tggtacattt accccattta
     1681 cgactggaaa gtggctgata tctggacctg gtatgcaaat catcaaagtc tctgcaaccc
     1741 actgtataac ctaatgtatc aggcaggcgt tcctctgcgt catatgcgaa tttgcgaacc
     1801 ttttggcccg gagcaacgac aaggattatg gctctatcac gttatcgaac cggatcgctg
     1861 ggctgctatg tgcgcacgag tcagcggggt aaaaagtggc ggcatttacg ccggacatga
     1921 caatcatttc tatgggcatc ggaaaatcct caagccagaa catttagact ggcaagaata
     1981 tgcattattg ctgctcaata gcatgccgga aaaaacagct gagcattacc gcaataaaat
     2041 cgccatttat ttgcactggt atcagaaaaa aggcatcgag gttccacaaa cccagcaagg
     2101 ggacattggc gcgaaagata tcccctcctg gcggcggata tgcaaagttt tactcaataa
     2161 cgattactgg tgtcgggcat tatcatttag ccccacaaaa tcgaagaact atcagcgtta
     2221 taacgaacgg ataaaaggaa aacgtcagga atgggggata ctatgcaaca acgattaacg
     2281 caggatttaa cgcaatttct cgccagcttg ccggaagatg atcgcatcaa agcgattaat
     2341 gaaatccgca tggcgatcca tcaggttagc ccctttcgtg aagagccagt ggattgcgtt
     2401 ctgtgggtta aaaacagcca acttatgcct aatgattaca acccaaacaa cgtggcacca
     2461 cccgaaaaaa aactgctgca aaaatccatt gaaatagatg gttttaccca acccattgtg
     2521 gtcacacata cggataaaaa tgccatggaa atcgtggatg gttttcaccg ccatgaaatt
     2581 ggtaaaggct catcatcatt aaaattacgc ttaaaaggtt atttgccggt gacctgtctg
     2641 gaaggtacgc gtaatcaacg catcgccgcg actattcgtc ataatcgcgc tcgtggacgc
     2701 catcaaatca ccgccatgtc ggaaatcgtc cgtgaactta gccagttggg atgggacgat
     2761 aataaaattg gcaaagagct gggaatggac agcgacgaag tgctgcgcct gaagcaaatt
     2821 aacggcctgc aagagttgtt tgccgaccgt caatattccc gcgcctggac ggttaaatag
     2881 ctaaagctgg cgcaggcgtt cagctgctgc cagcaacgtc gattccttct tggcaaaaca
     2941 gagacgaatc agtttatgtg ggaagggatc ggcgcaaaac accgacagcg gaatcgccgc
     3001 tacgccgtgc tcctgcgtca gccactggca aaactcaaca tcatccaggg tagaaaccgc
     3061 gctgtaatcc accagcaaaa agtatgtacc ttcacacggt aaaatctcca gccggctttc
     3121 atttaaagca ttcaccagaa tatcgcgctt ctggcgataa aagtccggta acgcaagata
     3181 atgctcaggt tctgcacgta gcatatcagc aagcgccagc tgtgccgggg tattcaccga
     3241 aaaggtcaga tactgatgta ccttgcgaat ttcggcgctg atgggcgctg gcgcaacaca
     3301 ataacccact ttccagccgg tcatatgata ggtcttgcca aatgaagaaa ccgccactgc
     3361 ccgctcacgc agctgcggat gcgccagcac actggcatgg ccctgttgtg aaaagttgat
     3421 gtgctcgtag acttcatcgc taatgacaaa aatctcgtgc ccggcgatcg cctgccacaa
     3481 agcggcgaaa tcagcctgct gccagacagt tgcactgggg ttatgcggag tgttgaggat
     3541 caccagtctg gtgcgctcgc ttaataatgc ggcaaattcc tgccagtcaa cgcgaaaatg
     3601 cggtggttgc agtgccatac gcttcactat tcccccagaa agcgcgatgg cgggggcgta
     3661 actgtcatag ctgggatcaa aacaaatcac ttcatcgcca ttgcgcacca gtgcggtaat
     3721 cgccgcgtat aacgcttccg tcgcccctgc cgttacggtg atatcgctat cggcatctgg
     3781 ttgatagcca tacaaacgtt ccgttttctg agcaatcgcc tcgcgcaagg cctgcacgcc
     3841 ggtcatgggc gcgtattggt ttgccccctg tgcaacgtgg tgcgccagcc gctcctgtaa
     3901 atagcgcgga ccatcaaaat caggaaagcc ttgcgacagg ttaatcgcct ggtgttgctg
     3961 cgccagcgcg ctcatctggg tgaaaatagt ggtgccaagt tgtggaagtt tgctttgtgg
     4021 aatcagaggg ttatttgtca tttttattgt acctgacgaa gttgcgtgtt gaaggcacta
     4081 taacacgatg ctagtatttg gcaatcaaga cgtttagatg tctaaataaa acaataagga
     4141 caacacaaca tgcctcacaa tcctatccgc gtggtcgtcg gcccggctaa ctacttttca
     4201 catccaggaa gtttcaatca cctgcacgat tttttcactg atgaacaact ttctcgcgcg
     4261 gtgtggatct acggcaaacg cgccattgct gcggcgcaaa ccaaacttcc gccagcgttt
     4321 ggactgccag gggcaaagca tattttgttt cgcggtcatt gcagcgaaag cgatgtacaa
     4381 caactagcgg ctgagtccgg tgacgaccgc agcgtggtga ttggcgtcgg tggcggtgca
     4441 ctgctcgaca ccgcgaaagc cctcgcccgc cgtctcggtc tgccgtttgt tgccgttccg
     4501 acgatcgccg ccacctgcgc cgcctggaca ccgctctccg tctggtataa tgatgccgga
     4561 caggcgctgc attatgagat tttcgacgac gccaatttta tggtgctggt ggaaccggag
     4621 attatcctca atgcaccgca acaatatctg ctggcgggga tcggtgacac gctggcgaaa
     4681 tggtatgaag cggtggtgct ggctccgcaa ccagaaacgt tgccgctaac cgtgcgactg
     4741 gggatcaata atgcgcaagc cattcgcgac gtcttgttaa acagtagcga acaggcgctg
     4801 agcgatcagc aaaatcaaca gttaacgcaa tcattttgcg atgtggtgga tgctattatt
     4861 gctggtggtg ggatggttgg tggtctgggc gatcgtttta cgcgtgtggc ggcagctcat
     4921 gccgtgcata acggtctgac cgtgctgccg caaaccgaga agtttctcca cggcaccaaa
     4981 gtcgcctacg gaattctggt gcaaagcgcc ttgctgggtc aggatgatgt gctggcgcaa
     5041 ttaactggag cgtatcagcg ttttcatctg ccgactacac tggcggagct ggaagtggat
     5101 atcaataatc aggcggagat cgacaaagtg attgcccaca ccctgcgtcc ggtggagtcc
     5161 attcattacc tgccagtcac gctgacacca gatacgttgc gtgcagcgtt caaaaaagtg
     5221 gaatcgttta aagcctgacg tacaaattta gcagcagcgc gcgccgcctt ttccaccgta
     5281 gcgcgcgtcc tgccgctcac ggaaaaactc ttcgtaggtc atcggcgttt gatcgggatg
     5341 gttaacccgc atatgttcga catagttgtc gtaatcaggc ataccaatca tcagcttcgc
     5401 cgcctgacct aaatattttc cggcttttgc cagtgaatca aacatcttgg cctccgctaa
     5461 ccatgttgct gaaagagtgc cggatgcggc gtgaacgcct tatccggcct acaaatgcta
     5521 tcaacgcgct cggtcagtcc cctcgcccca ccggggagag ggttagggtg agagggaacc
     5581 ctgggcacta agccaacatt cgccaacatc cccccctcac tctgacttta gtgtgcgcct
     5641 tttgcctgcg ccacgatctc ctcgacattt tccggcattg gttcatacgg cgtttctttc
     5701 gccgttggct tcggatcttt caatgccgca agtgccgtct taatcgagaa cagtgccaga
     5761 accaccacga ccaccataaa gaagatggtt aacccggcat ccagacggtt gttgaacacc
     5821 agttgcgcca gctgtgactc agtatactgc gacggaatat tgccgctgtc gatcattgcc
     5881 tggaacttat tagcaatggc caggaagccg actttcgcat ccgggctaaa cgctttctgc
     5941 cagcctgcgg tcagggtaca aatcagcagc caggccgttg gtaccagcgc cacccaggcg
     6001 taacgttgac gtttcatctt gaacaacacc acggcacaga gcatcagcgc catccctgcc
     6061 agcatctggt tggcaatacc aaacagcggc cacagagtgt taatgccgcc cagcggatcg
     6121 accacgccct gatggaggaa gtagccccac gccagtacgc acagcgctgt tgccagcagg
     6181 ttagcaggca gtgaatcggt ccgcttcagg ccaggagaca ccacgcccag cagatcctgc
     6241 aacataaagc gcgcagcacg cgtacctgca tccaccgccg tcagaataaa cagtgcttca
     6301 aacaaaatgg cgaagtgata ccagaacgcc acatccatca tgccgcccag cgcgccgtgc
     6361 agaatgtagg ccatccccac cgccagcgtc ggcgcaccgc ccgcacggga aatgatcgac
     6421 tgttcaccca cttcgctggc aatctggttt agcgtatctg gtgtaatgct aaagccccag
     6481 ctactcacca cctgcgcggc agaagcgacc acatccgccg tccctgccgg agccagcacc
     6541 gccatcgggc tgttcatggc aaaatacacg cccggatcga tgatacaggc ggaaaccagc
     6601 gccataatcg ccacgaagga ttccattaac atcccaccgt agccgataaa gcacgcctgc
     6661 ccttcgttcg ccagcatctt cggcgtggtc ccagaagaga tcagcgcatg gaagccagac
     6721 accgcgccac aggcgatggt gataaacagg aacgggaaca ggttaccggt ccataccggg
     6781 ccagtgccat cgacaaattt ggtcagcgca ggcatggtca gcgtcgggcg cataatcaaa
     6841 atgcctaccg ccagaccgac gatagtcccg attttcagga aggtagagag gtagtcacgc
     6901 ggggccagca gtaaccacac cggcagcacc gccgccacaa aaccgtaacc caccagcatc
     6961 caggtcaact gcacgccggt aaagtcaaag tacggtgccc aggtcggact ttctgccacc
     7021 cagccgccag agataatggc gaaaatcagg aataccagac cgatgaccga cacttcgcca
     7081 atacgccccg gacgcagata gcgcaggtag atccccataa acagcgccag cggaatggtg
     7141 aacgcaacgg tatatgttcc ccacgggcta tgagtcaggg ctttcaccac gatcatcgcc
     7201 agcactgcaa ggataatgac catgatcata aagcaggcca ccagcgcaat caccccggcg
     7261 gttggcccca tctcttcttt gaccagctca cccagcgagc gaccgtcacg gcgcgtagaa
     7321 acaaacagca ccatgaaatc ctgcaccgca ccggcgagaa ccaccccagc gagcagccag
     7381 atcatccccg gcaggtagcc catttgcgcc gccagtaccg gccccaccag cggacctgct
     7441 ccggcaatgg ccgcaaaatg gtgaccgaac agcactttct tgtccgtcgg cacatagtcc
     7501 agcccgtcgt tatggcgcac cgctggcgtc atacgcgtcg ggtcaaccgc cagcacattt
     7561 ttggcgatat acagcccata aaaacggtaa gcgatcagat agatacagac cgacgccacc
     7621 acaatccaca gcgcgttgat ctgttcccca cgatttaaag caatgtatcc tagagcaaat
     7681 gctcccatta cagagagcac tgtccagacg aggtatttcc ctgatttgtt catagttgtt
     7741 atccgtgtgc gtgtccatag agatgttaca ttttgtttct ataacatctt tgtacaattt
     7801 aacaacacag caaccatgta aatcggagtt gaaaccaata tttaacttaa caatgttaac
     7861 tcgatcactc cgttaaccga gttttcctgc aatctcatct aattctgtcg ggttcatccc
     7921 aaaactgccg tacccagccg acaagtgcag caacgccgcc cctgttcatc gaaaacgacg
     7981 atttcccagc tctgattttg ccgaccaaga tgcagcggct ggcagacgcc gcgtaccttt
     8041 ccctcagaca ccgggcgatg gtgtgttgca ttaagttctg tgcctaccac acactgtccg
     8101 tcgcgggtca tcataaatcc ggccatcgat cccagcgttt ccgccagcgc cgccgacgcg
     8161 ccgccatgta gtaaaccgaa cggctgatga gtacgggtat caaccggcat ttcggcttcc
     8221 agcacatcat cgcccagacg ggtatacaca attcccagat gcgccaccat tgtgttatcg
     8281 ctggtggcgt tcagttcgtc gagcgttaaa tggcgtttcc agatcatgct tatgccccca
     8341 gcgttgagcc gccatcgacc acaatatcct gtagggtaat atggctggcg aggtcagagg
     8401 cgaggaacaa aatcgtgttg gcgatctctt gtggacgggc gattttcccc agcggaatgc
     8461 cgagtttaaa ctgctcgcca aagccgcgaa tacgctgttc ttcggcgtca tcgctcaccc
     8521 acagcgtgcg ttgcatatcg gtgtcggtgg agccaggcga aaccacatta cagcgcacgc
     8581 cgctacccgc cagttccagc ccgacgctca acgccaggct tttcagcgcc gctttcgatg
     8641 cgccataagc actcatgcca atacgcggcg tgtgcgcggc gtcggacgcc acagtgacaa
     8701 tcgccccgcc ccgctgacgg cgaaactggt tcatggtttg ctggaacagg ttaaacgcac
     8761 cgccgacgtt aaccgcaaaa gtctgctgcc agtcctcttt actgagctga tcggtcgcgc
     8821 ccatgcgtaa aattcccgcc gcattgacca gcgcgtccag tcgctccgtt tcagctaaca
     8881 gtcgctgaca cacttgcgcg acctgcgcag cgtcggcaac atccatcact tcggtcgcaa
     8941 agggatattg ctcctgagtg aacgcttgat caaaacctgt aactttcgct cccgcctcaa
     9001 caaacgccag cgccgtggcg tagccgatac ctttacctgc gccggttacc cagacatttt
     9061 taccgctgaa atccattatt tcacctcgcg ggagagtagc ttccaccagg cgtcgatggt
     9121 cgggtttttc gccagcatga caaagtcgat atcaccatgc actttgcgcc agcgcgccgc
     9181 cagcgccatc atgcgcaccg aatccagacc gtagtcgatc aggttgtcgt catcgaacgg
     9241 ttcatcggac tcgtccagca acggcaggat cacctcacgc agcgccgctt tgctggcggg
     9301 gataggtgct ggcagtaatt cttcagtcat caccacccgg ccagaacgtc cggccacata
     9361 tttcagcgac atcaaatgct cgtcacggct gaaatcggcc agcgcatccg ccaccataaa
     9421 cggtttaata tcgcgcataa atgcgtcggt tgcggtggtc atacagccaa tgtgggcata
     9481 taccccggta ataatcagct ggttacgtcc actctctttc agcatttgct ccagcggaga
     9541 acgatgaaac gcgctgtagc gccacttcac cagcaccgtg tcgtcggcat ctggcgtcag
     9601 gcgatccacc accttttgct gttccggcga gcgggtcagg cccggccccc acatatcatt
     9661 caacagcgcc cgatcttcat cgctctgctc tttcggctgg gcggtgtaat aaaccgggat
     9721 attgtgctgt ttgcagtagt cgcgcagcgc agcaatattc gcgatcacct gctccatcat
     9781 cgggcagttc tcgccccaga agctgacaaa atagtcctgc atatcatgga ttaacaacgc
     9841 ggcacgttgc ggttcaaagg cccagtcaac tttattctgc ggaatatcgt gagactccgg
     9901 cagtgcgtaa gcctgtaatt ttggaatagc catcgtgttc tctccttcag gctgatgcgc
     9961 gtgacgccag ccactgacgt aattgttttt tatcgacttt cccgaccgcc gtcagcggaa
    10021 gtgaatccac acactccacg cgatccggta atttaaattc ggcaataccc tgttcacgca
    10081 ggaaacgacg cacctgcacc gcgcgcagcg gctcttttac caccagataa gcgcagcttt
    10141 tttcgcccat cagctcatct tccatgctca ccagtgcggc gtagatcacc gccgggtggc
    10201 gcagcagcag gttttcgatc tcttcggcag cgatcttctc gccgccacgg ttaatctgat
    10261 ctttctcgcg cccctgcacg gtgatgtaac cctctggatc aatagagatc agatcgccgg
    10321 aacagtaaaa accgttggca tcaaaggcgc tggcattgtg ctgtggactt ttgtaatagc
    10381 cgcggaaggt gtacggcccg cgcgtcatca ggcgtccgac ttccccttgc ggcagtggat
    10441 ttccttcggc atcggcaacc catacttcgt catccggaca cattgggtaa ccctgggtat
    10501 ggataatttt ctccgcgcta tcatcaagtc gggtgtagtt caccagccct tccgccatgc
    10561 caaacacctg ctgcaactga cagccaatct cagcgggaat acgcgccgca agggtggcag
    10621 aaagacgtgc gccgccgacc tgtaacagtt tcagcgaggc aagctgcgcc cggctttcgc
    10681 cttcgatcag cgcctgcaac cacaggctga ctgcgggtgg caccagcgcg gtaacgttaa
    10741 cctgatgttt ttcaatcaat gggaaacaga gcgtggcgct gggatcggcc gccagaacaa
    10801 ccgttcctcc ggcaagaaag acgcccagcg atcctggcga actcatggcg tagttatgag
    10861 ccgccgggat cgcgcacagg tagcgtgtct gttgtgtgaa ctgacaaatc tcgacgctac
    10921 gacgcacgct gtagtagtag tcgttatgag tgcgcgggat cagtttcggt gtgccggtgg
    10981 tgccaccgga aagctggaaa taggccactt catcagcagg tgatggcgtg gcagtaaaat
    11041 cctcagccgg atggttaatc gcatcctgca agttatgctc accgctgtcg ttgagcagtt
    11101 gcaccacgcg aatggaggaa tgttctgtga cgaaagtatt gaggaaatca tccccgctaa
    11161 acagcgcatg ttggcgatcg gcaatcagca atgcgggttc aatctggctg gcataggcgt
    11221 tcagttcact acgctgatgg ctgaacaacg ccagcaccgg cgcaacgccc agtttcagca
    11281 gcgcgaaaaa ggtaatatac aattcagcga cgttacccag ttgtaccagc gcggtttcac
    11341 caggtttaat gccctgacgg cgtaaactac acgcgaggtt atccgccgcc tgattcagct
    11401 cccgataact caactgtcgc tcgccgtcga taaccgcgat gctgtcactc gcagcatgtc
    11461 gcgtcagaat gtcggtcagc ggcaaatcct gccagtagcc tttttcccga tagcgacggg
    11521 caaactcttc cggccagcgg gtgaatggaa tgctcatcct cgctccttaa tgcaatccaa
    11581 aaacgttcaa catggtagaa agtttgacgc ctgtttcgcg ccactcaccc aacggtgacg
    11641 acgcaggcac aatccccgct ccggcaaaca gacgcacctg attttcccgc agcttcgcgc
    11701 agcggatggt caccacccat tcgccgttac cttcgctgtc acaccaaccc acaatgccgc
    11761 caaacagttc gcggtcgaac ggttccagtt cagcaataac ctgggtcgcg gcctgatgcg
    11821 ggaaaccgct cagcgcgggg gtcggatgca gcagacaggc cagagtcagt gcgttttctt
    11881 gcgaattcgc tttaccttca aagggagttg cgagatgcca cagcgtcggc gtggtgatca
    11941 gctgtggaga agaaggaacg tgtaactcac tactgcgttc gcgcagtacc tctttcatcg
    12001 cctgagtcac cagttcatgt tcatggcgat ctttttctga cgccagcaga cgattacctg
    12061 cttcgcgatc gagcacttca tccggctgac gacgcgcgga accggctaac ggaatggagc
    12121 taaaacgctc gccgtcttta cgtagcagca gttccgggct ggcccccagc aggacgccac
    12181 catcagccag cggaacatgg aagttgtaac taaccgggtt ttgcgcaatc aaccgttcca
    12241 gcaatacgcc actatcaatg gcggcgtcag tggtgatatc aatcaaccgt gacaacacca
    12301 ctttgtcgac ctgcggcgtg gcggtaagtg cggcggcgcg ggcaaccatc tgttcaaacg
    12361 tggtttgctc cggaattgcc tggcgttcca ccacattcag cgactggctg cgggtgaaac
    12421 ggcgtgcgga agcttgtttt tcctgacggg agaacgactg ccaggattca ggaatataca
    12481 gcgacgaagg ctgacgtgga tcgaagggaa tcgccccgac catcaccgga tttttgatgc
    12541 cctgcgcttt ggcatcggca aacagcgcgg cgagtttttg ctggaaggga ctgtcgggcg
    12601 aatccccgtt cacagccggt tcatcgaagc gggcgaaaca tcctgacgtc gtaaaactgc
    12661 ggtacggcga cataaagaaa aagcgattgg gcgcaagtgt tgccatggtc tgctgtactt
    12721 cctcagccag tgacgtatcc atatcatcct ccacaaaatg ataaaggctt taataatgat
    12781 tatcatttat attttcggtc gctaacctaa aagcaaacgc gcactatgtc aactcttgag
    12841 gtaacgcaat ctgcaactcg gggttgcatc tggttgtggt tacaatgaaa atgagaagca
    12901 ttattgatgg attcgcataa gcgcaatgtg atgtcctgcg ccgttctgcc ccctctccct
    12961 tccagggtga gggctggggt gagggttaat gttcgcacca gtgctggctg ttcccctcac
    13021 cctaaccctc tccccaaagg ggcgagggga cggattgtgc gctttgtcga atttgtcatt
    13081 acgcccttaa ccttattaat aacaggaagc tgatttgtga gactcgcccc gctctaccgc
    13141 aacgcccttc tattaacagg acttttgctt tcaggaatag ccgcagttca ggccgctgac
    13201 tggccgcgtc agattactga cagccgtggc acacatacac tggaaagcca gccgcagcgt
    13261 attgtttcca ccagcgtcac cctgaccggc tcactgctgg cgattgatgc tccggtgatc
    13321 gccagcggcg cgaccacgcc gaataaccgc gtcgcggatg accagggctt tttacgccag
    13381 tggagcaagg tggcgaaaga acgcaaactg caacggctct atatcggcga accgagcgcc
    13441 gaagccgttg ccgcgcaaat gccggatctg attttaatta gcgcaaccgg cggggattcg
    13501 gcgctggcac tgtatgatca gctttccacc atcgccccga cattaatcat caattacgac
    13561 gacaaaagct ggcagtcgct gttaacgcaa cttggcgaaa ttaccgggca tgagaaacaa
    13621 gcggcagagc ggattgcgca gtttgataag caactggcgg cggcgaaaga gcaaatcaaa
    13681 ttaccgccgc agccggtcac tgccattgtc tatactgccg ctgcacacag tgccaatctc
    13741 tggacgccag aatcagcaca agggcagatg ctggaacaac tcggctttac gctggcgaag
    13801 ttacccgcag ggttaaatgc cagccaaagt cagggtaaac gccatgacat cattcagctt
    13861 ggtggggaaa atctggctgc agggttaaat ggcgagtcac tattcctgtt cgccggtgat
    13921 cagaaagatg ccgatgctat ttatgctaat ccgctgctcg cgcacctgcc tgcagtacaa
    13981 aacaagcagg tttatgcgct gggaaccgag acgttccgtc tggattacta cagcgccatg
    14041 caagtgctgg ataggcttaa ggcgctgttt taagcattaa ctgtcggacg ctgtcacctg
    14101 cggcggcgtc tggcgaaaat gtcgcaactc caccagcacc agcaataaca acacgccgat
    14161 aatcaacaaa ccaaaaccgc tcgcgcttgc ggaagcaacc ggtgtcatca tcgcgcccaa
    14221 accacccagc agcgccgcgc ctatggcatc gcccgtcacg ttctgcgccg tccacaaacc
    14281 gttaatccgc cctaacatcg cttccggggt ttgcgtttgc agcattgtgt attgcagcaa
    14341 cgagctgacc gcactcaacc agccgaacag cgccagacaa accacgccta aaatccacat
    14401 cggcatcagg ccaaacagac caatggcgag gaacgatccc agcgtggaga gcagcatcaa
    14461 taaccctggt cgcgcactat gtgccagctt cccgctggtt aacgcaccaa tagccgcgcc
    14521 gagcgggatc gccgcgtaga gaaaaccaat ctgtgccgct gacatctgcc agttgtcagc
    14581 cagcgccgga tacagtaccc gcaccgcgct cgccatcgtc aataaaccac ccagcagcgc
    14641 aatcccgccc accagcgggc tggcaagcag aaaacgaaat cctgccagta atgatttcaa
    14701 cggatgctca cgcggctgcg gtggcggtgg caacgccgga aggcttaaca acggtagcaa
    14761 ggtaataaac gtgcccgccg ccgccagccc gtagttccag gctacgccac cggtcgccag
    14821 caataaaccg ccaatcatgg gcgaaatcac cgaccccaga cgcacggtca acatggtgat
    14881 cgccccggcc tgcattaagt tttcacgccc taccagtgct ggtgtcgccg ccaatagcgc
    14941 cgtaacgcca agcgatgcga aaaaaccatc ccataaacca agtaaataga ttgccagcaa
    15001 tgacggctcc ggcagcagtg cattaaggca cagtccaatg aagccaatgc cacaggtgcc
    15061 gcgcgccagc aaaatcactt ttttgcgctc atagcgatcc gccagcacac cgccgaccat
    15121 caggccaaca aacatcgcgc cgccggtcag cgtcaccgaa agccccacct gccaggtgga
    15181 atgtgtcatc atctggatct gcaccggcac cgcgacgccg agcaaaccca gagacacaat
    15241 tgagatgaaa cgagcgagga atactgcgcg aaacgccggg tgcgttttca acaggctgag
    15301 gttaagcagc caggattgtt tattcattac aatgccttgc catcaaatat tttaaatacc
    15361 tattcttagg ctgcacatgt taacatatcc aaataagatc gataacgata attaatttca
    15421 ttatcatgga agttcgtatg tctggttctg ttgccgtgac acgcgccatt gccgtgcccg
    15481 gattgctgtt attactgatt atcgcgacgg cattaagcct gctcattggg gcaaaatcac
    15541 tccccgcttc cgtagtgctg gaggccttct ccggcacctg ccagagcgcc gactgcacca
    15601 tcgtgctcga cgcgcggctg ccgcgtaccc ttgccggttt actggcaggc ggcgcgcttg
    15661 gccttgccgg ggcgttaatg caaaccctca cccgaaaccc acttgccgac cccggcttgc
    15721 ttggcgtgaa cgccggagcc agctttgcca ttgtgctggg tgcggcgctg tttggttact
    15781 cttccgcgca ggaacaactg gcgatggcct tcgccggggc gctggtggcc tcattgattg
    15841 ttgcctttac cggcagtcag ggcggcgggc agttaagtcc ggtgcgttta accctggcgg
    15901 gcgtggcgct ggcggcggtg ctggaaggac tgaccagcgg catcgccctg cttaatcctg
    15961 acgtctacga tcagttgcgt ttctggcaag ccggttcgct ggatattcgc aatctacata
    16021 ccttaaaagt ggtgctgatc ccggtgctga tcgccggagc aactgcgcta ttactgagtc
    16081 gcgcgctgaa cagtttgagc ctcggcagcg acaccgcgac ggcgctgggc agtcgcgtgg
    16141 cgcgcacaca gttgattggt ctgctggcga ttaccgtgct ttgtggtagt gcgacggcaa
    16201 tagttggccc gattgccttt attggcctga tgatgccgca tatggcgcgt tggctggtgg
    16261 gtgccgatca tcgctggtcg ctgcccgtca cgctacttgc tacccctgcc ctgctgctgt
    16321 ttgccgatat catcgggcgg gtgattgtgc ccggcgaact gcgcgtttct gtggtcagtg
    16381 cgtttattgg tgcaccggtg ctgatcttcc tcgtgcgacg taaaacgcga ggtggtgcat
    16441 gatttacgtc tctcgccgat tactcatcac ctgtttgctg ctggtttccg cctgtgtggt
    16501 tgcaggtatc tggggattac gcagcggtgc cgtcacgctg gaaacctcgc aggtattcgc
    16561 cgcgctgatg ggcgatgcgc cgcgcagtat gacgatggtg gtcaccgaat ggcgtttacc
    16621 acgcgtgctg atggcgctgt tgattggcgc agcactgggc gtcagtggcg cgatttttca
    16681 gtcgctgatg cgtaacccgc tcggcagccc tgacgtaatg ggctttaaca ccggggcgtg
    16741 gagcggcgtg ctggtggcga tggtgctgtt tggtcaggac ctgacggcta tcgcgctgtc
    16801 agcaatggtg ggcggcattg tcacttcgct gctggtctgg ctgctcgcct ggcgcaacgg
    16861 catcgacacc tttcggttga ttattatcgg tatcggcgtt cgcgccatgc tggtggcctt
    16921 taatacctgg ctgttgctga aagcgtcttt agaaacggcg ctaacagcag gtttgtggaa
    16981 tgccggatcg ctcaacggcc tgacgtgggc aaaaacctcg ccttccgcac ccatcattat
    17041 attgatgctc attgccgccg ccttactggt acgccggatg cgcttgctgg aaatgggcga
    17101 tgataccgcg tgtgcgctgg gcgtcagcgt cgaacgttcg cgtctgttaa tgatgctggt
    17161 tgcagtggtg cttaccgctg cggcaacagc gcttgccggg ccgatttcct ttattgcttt
    17221 agtcgcaccg cacattgccc gacgcattag cggcaccgct cgctgggggc taacccaggc
    17281 ggcgctatgc ggggcgctgt tactgctggc ggccgatctc tgcgcccaac aactgtttat
    17341 gccgtatcaa cttccggttg gcgtcgttac cgtcagcctc ggcggtattt accttatcgt
    17401 cttgttaatt caggagtctc gcaaaaaatg accgaatcag tagcccgttt gcgcggcgaa
    17461 cagttaaccc tgggatatgg caaatatacc gttgcggaaa atctgactgt agaaatacct
    17521 gatggtcact tcacggcaat tatcgggcca aatggctgcg gtaaatccac gttactgcgt
    17581 accttaagcc gcctgatgac gcctgctcat gggcatgtct ggctggatgg cgagcacatt
    17641 caacattacg ccagtaaaga ggttgcacgc cggattggtc tgttggcgca aaatgctacc
    17701 acgccgggcg atatcaccgt gcaggagctg gtggcgcgtg gacgttatcc gcatcaaccg
    17761 ctgtttaccc gctggcgcaa agaggatgaa gaagcggtaa cgaaagcaat gcaggccacg
    17821 ggaataactc atctggcaga tcaaagcgtg gatacccttt ctggcggaca acgccagcga
    17881 gcgtggatcg cgatggtgct ggcccaggaa acggcaatta tgctgctcga cgaacccacg
    17941 acctggctgg atatcagtca tcagattgat ttgctggagt tgttaagcga actgaaccgc
    18001 gaaaaaggct ataccctggc ggcggtgctg cacgatctta atcaggcctg tcgttacgcc
    18061 agccatttga ttgcattgcg ggaagggaaa attgttgctc agggagcgcc gaaggagatt
    18121 gtcactgctg aactgattga gcgcatttat ggtctgcgct gcatgatcat tgacgatcca
    18181 gttgccggaa cgccgcttgt ggtgccgctc ggacgaacgg caccttcaac cgcaaatagt
    18241 taaactaagt ggtctgccat catggcatcc tgttttctgg atgccatcgc atagcgcaac
    18301 agcacgccac cacaagccac catcccgccg atcaacgcgg aaaggatcac aataatcgcc
    18361 ttacccggac cgtctttttt cactggcaat gacgggctta actgatattt aaacggcgta
    18421 aaattcacat cgttgacatg tgcttttgtt aattgctcga caagatactg ccgattacgt
    18481 aattcaccgt tcagttccgc aacgtcagtg accgcttttt ctatttccag tttgcgttca
    18541 ataccgtctg caccgagaga aatagaaaaa tcggggtcat ctttaacggc ctgaccatta
    18601 ctgtaaacgg gctttttaat tcctgccgcg ttggcaatgt cgagtgaata attgaggcgc
    18661 tgaatgtttg catcaagttg atttttcgtt ttaatgcgat cctgagccag tttttctttt
    18721 tcaaactggg ttttgatctc cagtttatta cggacgtttt ctagcgactc tttcaccacc
    18781 aacgtagaga tataatcgat atacccgctc aaaacggtct gcgcctcttc actggttggc
    18841 gcggtaaaac ttagcgtcca ggaggtatac agtgacggtt catctttttt cttactggca
    18901 ttgtcatcaa ccgctttcat tttttcgctc aatgcgacaa ttgcgcgatg caaatccagt
    18961 tcgtcgattt tcgcctcttt taattggtcc atcacataag gtgatgaacg caggtactct
    19021 tccagcaagc taaccgactg aaacttcttg ataaacaggt taaatgcttc tgtacgatca
    19081 attttgatat ccagatccag cacacgaagc ttagtgaatg atttctccaa ctcttgccac
    19141 tgaacaggtt ctggaggcgt gacaaccgcc gcgctggtcc atttttgcgg caggatgaaa
    19201 gagatcagca agcctgcgca ggcaaacgca aaaacgaccg ccatgaccgt ttttttggcc
    19261 cgccataaaa ctgagattag attaagtaaa tcaatttcat tattactgga cgacgccaga
    19321 ggataatcgg gaaaatgagc gtcacttccc tgtttaatat tcagtgatga catggggtat
    19381 aacctgaaaa tgagtccaat agggggaaat ctccacggcg ctcactttac cagttggtga
    19441 taattatccg aagctgaagt ttgtaaattc cttccactga atgcaacatt cactctattt
    19501 aagagaaata ttcatcaaac ctataaatca aacaaataaa aaacccataa ttattttctg
    19561 taattatggg tttataaata atattaattt acctgtttag cgttgcgcga ataatcggcc
    19621 caattttttc aaacgtccct ggagagataa tatccacatg cgcacaatcc tgacgataga
    19681 tatccagctc cgctatccac ggcgaccagg cgcgttcggg actcatacct tcctgaagtg
    19741 tgcgttcagc aacaaacagc gtcgctttac cgtcaaacgg tacgctatga gcagtcgtca
    19801 gcaggcgcac agcatcagcg tagttgcctt caatggtggt aaacaactcc gttgaagtac
    19861 ttccctgctg tgctgccagg aaggcctcgc gttcgcggtt aatctccgcc agcacttccg
    19921 ggtccagacc attagcttct ttttcctgcc agttttgcgt ttctggcggc caggtatcca
    19981 gcaagccaag aaatgccacc tgttcgccac gggcacgcag tcgcgccgca ataccctgcg
    20041 ccagcgtacc gccaagggaa taccccagca ggtaataagg gccatgcggt tgttgttcaa
    20101 gtaacgttgc cagatgcgct tcgcagactt catccaggtt tgccgccgtc tgcatggggc
    20161 cattggggcg cggtgactga atgccgataa tcgaccattg tggatcgaga taacgcgaga
    20221 gcacgctgaa ctgccaggca aaaccggacg caggatggaa acaaaacagc gtcgggccat
    20281 taccttcacg caacggcaga atggtttcga atcccatacg ccgggtgctg tcttcttcag
    20341 catcaataat cgttgccagt ttggcgacag ttgacgcgac catcacttgc cccggcgtca
    20401 cctggcgggc aacctgccga cttaactgcg ctgccagttt cattgccagt agcgaatgac
    20461 cgccaagcgc gaagaaatca gcatcggcat cctgcacgtc acaccccagc aacgacgaga
    20521 atgccgcggc gataatcgtt tcactgcccg ctttcggcgc acgccctggc gcttgtgcct
    20581 tcagttcagg caacggtaag gctttgcgat ccagcttgcc gttggcgcta agtggtaact
    20641 gtggaagttg cagcagaacc accggtacca tatgtggtgg caatgtttca cgaagctgcg
    20701 cctgcaatgc gctggtatcc aacggcaggc ccgattgcga caccagatag cccaccaatt
    20761 gacgcgcatc accaccggtg gcagccgcct ggttaatcac acaggcgtgg gtaacggctt
    20821 gttcgacatc cggcagcgcc tgcatcacgc gatcgatttc gcccagttcg atacgctgcc
    20881 cgcgaatttt tagctgatca tcactgcgcc cgaggtactc caccgcgccg ttatccagcc
    20941 agcgggcaac gtctccggta cggtacatcc gttcacctgg ggcaaaagga tcggcaataa
    21001 agcggctggc ggtcagatcg gggcgtccga gatagccctg cgccagttga atgccagtga
    21061 gatagagatc acccgccaca cccggcggca ccggatgcat catcgcatca agaatacgca
    21121 gacccgtatt ccataccgga taaccaatcg gcacactgct gccgcgcacc tgtgccagtt
    21181 cctcgccaaa agccggatac cagctgacat ctaccgccgc ttccgtcggg ccatatagat
    21241 tatgcaacgg cgcgccagtt aactgttgcc attcgcggca taaatcagcc ggtaaggcct
    21301 caccactaca gaaaacctgt ttcaacgtcg cgcaactctg gcgagcggtt tgcggcgtca
    21361 gcgaggcaac aaatgccgcc agcatcgacg gcacaaagtg cgtggtcgtt acgccatatt
    21421 cggcaaagaa ttgctgcata gcgagcgggt cgcggtgcgc ttccggttca gccatcacca
    21481 gttttgcccc tgcgataaac ggccagaaaa actcccacac cgagacatca aaactgcacg
    21541 gcgttttttg ggcaacgaca tcttcgcctg taagcggata atgattttgc atccaaagca
    21601 ggcggttgac gatagccgtc tgcccgacca ttaccccttt cggcctgccg gtggagccag
    21661 aggtaaagat gatataagcc gtgtgatgcg gttgtgaaag ttgcagcggc gcactgccct
    21721 gcggtgtaag cggggcgtta tagcaaaggc ttgttaaatt gggaacatcg ctaaagcgcg
    21781 gcagttgatc gtcggtggta attaacagcg acggacgcgc atcttccagc atcattttca
    21841 ggcgatcgtc cggatagccg gtatccagcg gtagccaggc cgctccagct tcaactatcg
    21901 catggagtgc cagggtcaaa aagaccgagc gcggtagtgc caccgccacg ctgtcccctg
    21961 gtttaacgcc gcgctcacgc agcagattcg ccagcgccac cacctgctcg cgcatttccc
    22021 gatagctgaa caggtaacgc gcatctgcca gcgccggagc atccggtgtt tttgccgctt
    22081 gttctgccac cagcgcgcta agcgtggttt ctggaatctc aacctgagtg gcgttgagct
    22141 gcgccagctg cgcatactca cctggcagca taatatcgac atcgccgcac aacagcgccg
    22201 gatccgcggc gaactgggca atcagcattt tcaggcgttc agcatgctgg attaacgttg
    22261 gctcatcgta acgctgttta ttggcgagga tctcaatact caaatcaccg tgtacatccg
    22321 ggaacagggc cagttcaagg tcattaaccg gaccggttgc cagggtatgg gtttgcgcct
    22381 gaacatcagg aatatccagt tggtaatcaa ataccttgat attgagtacc ggaccaaaca
    22441 gcggttcatc acctgccgct cgcccgctgt cacggacaat ttgttcggca tcgtaacgtt
    22501 gatgacgacg catttttttc agttgtgctg ccagtcgggt tgccagttcc ggcagcgttt
    22561 cttgcgccgc aatgtgaata cccaacggca aaacgttgag cacgggtccg gtagccgtca
    22621 gcgccgccga gcccagtcga cgcataaaga taaatccggc ggcgtagtcc atacgattgc
    22681 acaatcgccc cagccacaag gctgccagcg caagggctaa atcggtacgc tgcacacctg
    22741 aaagttgcgt agccagctgg cggaattccc cgtcggtaaa ttccagtttc aggcgcagaa
    22801 tatctgccga ggcgctgcgc cccggtaaag gtgccggaga aagtgacgcg ggcggcggca
    22861 gttgacgacg ctgttctgcc cagaatgccg catcacgctg ccaggcttcg ctttcgcggt
    22921 attgctggta ctcttccact acatcagcga aaggcgtaaa tggcgaagca ggcgttggtt
    22981 cgccacgcag ccatgtgcag taaatattgg cgatctggcg ggtaatggcc gggaaactaa
    23041 agccatcgac cagcaaatgg tgataacgct gataccagta ccagcggtta tccgccacct
    23101 gtatcagctg atgaaagacc agtggtttac cgctatcgac gcgcagatct tgttgcaaat
    23161 ccgcctgcat taatgcctgc gcagtaccgt gcggatcaat gttggttcgt aggtcgataa
    23221 tttctggcag ttcgaacgtc agcgcatcat cgacccactg ccagacttcg ccgttatctt
    23281 ccgtaaaacg catccgcagc gtatctgctt gcgctagtcc ggcaaccacc gcgcgggcca
    23341 gtaatggcga atcaacctct ccggttaact caacgtaatg cgccacgctc caggcggagg
    23401 gtaattctga cagtttttct gccatccaga tgccgggctg tgcggcgacc aaaggtaaat
    23461 gctggctcat tgtgcctcct gcaactgggt aaaattcgtc ggtgtcagag tacgccagtg
    23521 ggcttccagc cactgctggc aggacgcctg tgactgcggc tgacacacaa tgtcccagcc
    23581 tgccggtaag acgcattgtt gcggccacag actgaattgc ccctgcgcat tgcgcaatat
    23641 gtaaaacgct ccctgcggat catcgaaggg attactgaat gccatattca actcctgtca
    23701 tggaaaagtg gttgccagag gtcgattagc ccctgcatca agccaccgcg ccaacaaagc
    23761 gcatcatgtc cgccgtcaac ctgacgccag aaaatggatt cttttatggg gtgtaattgc
    23821 gcatacagcg cctgattggc ccgcatgatc atcggctcgc gaatacccgc ttccagcaca
    23881 atgcgcagac cttcggcgct aacttcacca gcttttagct tttcaagtaa cacgccctct
    23941 tgctgcccgc cccgatgcgg ccaccagtac gatcctgact ggcttaatac acagccaaag
    24001 cgttcaggcc agtgcagtcc ggcatacagc gcggaaagcc caccaaaact ctgcccggca
    24061 accacggtgc gatcggcacg atcgctaaaa ggggcaatag ctttcaccag gggtaataac
    24121 tcttgctgta ctgcgagcca gaaatccgca ttacacggca gttcgtgggc gcggtgcgtg
    24181 gtgtcgatag cgtcgatcaa cacatacacg gcgggaggaa gttgctgacg atgggtcagc
    24241 gaagtcagca ctggccagac gggcatactt tgcgcccaaa attcgccatc gagcaaaact
    24301 gccagcgggc gttcttctgc tgttgcatcg ccggtggtaa aaatccatac acgccgtgac
    24361 tttttcaacc gttcactttt ccagataatt tctttggcag gtatttctgg cgcttgcgga
    24421 caatcccatc ccggttgcag aggcgcttgc ggcatttcga gtgcagaaac agcgtgccct
    24481 cgcccgcctt tccagctttg taggttcagc ggatcggcta tcgcctgggg taatagtttt
    24541 cgccagcctt cgcgcaattc gaggcgatcg ggggatggta cagaaaaaat gtcatcgcgt
    24601 tcggtgggaa taaagcagta gctgccgcgc cagttggcat tgagttgtgt cgtccactgc
    24661 cagacgttag tgcctgcaat tcgctgcatc gactggggct ggctgttctg atggtgatcg
    24721 gtcacaccag tgatgtagac ccatacgcgc tttatcgtcg agtattcttc agaaccttgg
    24781 ggatcacgcc accagaaagt gacctcaaac atttcgtcat tcagacgctg ccattccggg
    24841 ccatgtttcg actgccacca gctctcactt cctactttta acgccgtcac accataaccc
    24901 catgtttact gtgcaatttt tcattgattg cagaaatata ttgataatat tattgataac
    24961 tatttgcatt tgcaataccg taatggcgcg ccgtgggaag cgcggacatt aattaaccaa
    25021 ctgcactgcg tgtctttcag gatcaaaggt tttcgcggta gcgggatgcg tcgtgttgat
    25081 gacgaccatg cccgacagtt gcaattcgtg gcaaaaatgc aggaataaaa caatgaacaa
    25141 gaagattcat tccctggcct tgttggtcaa tctggggatt tatggggtag cgcaggcaca
    25201 agagccgacc gatactcctg tttcacatga cgatactatt gtcgttaccg ccgccgagca
    25261 gaacttacag gcgcctggcg tttcgaccat caccgcagat gaaatccgca aaaacccggt
    25321 tgcccgcgat gtgtcggaga tcatccgtac catgccaggc gttaacctga ccggtaactc
    25381 caccagtggt cagcgtggga ataaccgaca gattgatatt cgcggtatgg gtccggaaaa
    25441 cacgctgatt ttgattgacg gcaagccggt aagcagccgt aactcggtgc gtcagggctg
    25501 gcgtggcgag cgcgataccc gtggtgatac ttcctgggtg ccacctgaaa tgattgaacg
    25561 tattgaagtt ctgcgtggtc cggcagctgc gcgttatggc aacggcgcgg cgggcggcgt
    25621 ggttaacatc attaccaaaa aaggcagcgg cgagtggcac ggctcctggg acgcatattt
    25681 caatgcgcca gaacataaag aggaaggtgc caccaaacgc actaacttta gcctgaccgg
    25741 tccgctgggc gacgaattca gcttccgttt gtatggcaac ctcgacaaaa cccaggctga
    25801 cgcgtgggat atcaaccagg gccatcagtc cgcgcgtgcc ggaacgtatg ccacgacgtt
    25861 accagccggg cgcgaagggg taatcaacaa agatattaat ggcgtggtgc gctgggattt
    25921 cgcgccattg caatcgctgg aactggaagc aggttacagc cgccagggta acctgtatgc
    25981 gggcgacacc cagaatacca actccgattc ctatacccgc tcgaaatatg gcgatgaaac
    26041 caaccgtctg tatcgccaga actacgcgct gacctggaac ggtggctggg ataacggcgt
    26101 gaccaccagc aactgggtgc agtacgaaca cacccgtaac tcgcgtattc cggaaggtct
    26161 ggcgggcggt accgaaggga aatttaacga aaaagcgaca caggatttcg tcgatatcga
    26221 tcttgatgac gtgatgctgc acagcgaagt taacctgccg attgatttcc tcgttaacca
    26281 gacgctgacg ctgggtacgg agtggaatca gcaacggatg aaggacttaa gttccaacac
    26341 ccaggcactg accggaacga ataccggtgg cgctattgat ggcgtgagta ccaccgaccg
    26401 tagcccgtat tcaaaagcag aaattttctc gctgtttgcc gaaaacaaca tggagctgac
    26461 tgacagcacc atcgtaacgc cggggctgcg tttcgatcat cacagtattg tcggcaataa
    26521 ctggagcccg gcgctgaaca tatcgcaagg tttaggcgat gacttcacgc tgaaaatggg
    26581 catcgcccgt gcttataaag cgccgagcct gtaccagact aacccgaact acattctcta
    26641 cagtaaaggt cagggttgct atgccagcgc gggcggctgc tatctgcaag gtaacgatga
    26701 cctgaaagca gaaaccagca tcaacaaaga gattggtctg gagttcaaac gcgacgggtg
    26761 gctggcgggc gtcacctggt tccgtaacga ttatcgcaat aagattgaag cgggctatgt
    26821 ggctgtaggg caaaacgcag tcggcaccga tctctatcag tgggataacg tgccgaaagc
    26881 ggtggttgaa ggtctggaag gatcgttaaa cgtaccggtt agcgaaacgg tgatgtggac
    26941 caataacatc acttatatgc tgaagagtga aaacaaaacc acgggcgacc gtttgtcgat
    27001 catcccggag tatacgttga actcaacgct gagctggcag gcacgggaag atttgtcgat
    27061 gcaaacgacc ttcacctggt acggcaagca gcagccgaag aagtacaact ataaaggtca
    27121 gccagcggtt ggaccggaaa ccaaagaaat tagtccttac agcattgttg gcctgagcgc
    27181 gacctgggat gtgacgaaga atgtcagtct gaccggcggc gtggacaatc tgttcgacaa
    27241 acgtttgtgg cgtgcgggta atgcccagac cacgggcgat ttggcagggg ccaactatat
    27301 cgccggtgcc ggggcgtata cctataacga gccgggacgt acgtggtata tgagcgtaaa
    27361 cacccacttc tgatgctaac gtcagattgt tgacaaagtg cgcgtcgttc atgccggatg
    27421 cggcgtgaac gccttatccg gcctacaaaa atcttgccaa ttcaatatat tgcaggacca
    27481 tgtaggcctg ataagcgtag cgcatcaggc agttttgcgt ttgtcatcag tctcgaatat
    27541 ggtcgatatg aaaactacgc atacctccct cccctttgcc ggacatacgc tgcattttgt
    27601 tgagttcgat ccggcgaatt tttgtgagca ggatttactc tggctgccgc actacgcaca
    27661 actgcaacac gctggacgta aacgtaaaac agagcattta gccggacgga tcgctgctgt
    27721 ttatgctttg cgggaatatg gctataaatg tgtgcccgca atcggcgagc tacgccaacc
    27781 tgtctggcct gcggaggtat acggcagtat tagccactgt gggactacgg cattagccgt
    27841 ggtatctcgt caaccgattg gcattgatat agaagaaatt ttttctgtac aaaccgcaag
    27901 agaattgaca gacaacatta ttacaccagc ggaacacgag cgactcgcag actgcggttt
    27961 agccttttct ctggcgctga cactggcatt ttccgccaaa gagagcgcat ttaaggcaag
    28021 tgagatccaa actgatgcag gttttctgga ctatcagata attagctgga ataaacagca
    28081 ggtcatcatt catcgtgaga atgagatgtt tgctgtgcac tggcagataa aagaaaagat
    28141 agtcataacg ctgtgccaac acgattaatt gacaacatct ggtacgattc gcccgcagcc
    28201 atcactgacc acgggcgaaa gtgtaaagca ggtgccttac catcctgacc tgacaaccgg
    28261 atatgcgggg attactccca taagcgctaa cttaagggtt gaaccatctg aagaatgcga
    28321 tgcctcggtg cctcgttaag acgatgcctc gcgttcttca attgcgtttt gtaggctgtc
    28381 agggatactg tcccacgaat ggccacctgt aagctccaga tgaccatttt tgttattctc
    28441 cacaacgagt tagttcttct tttcggatcc ggcacttctg ggggggaaat ccagcgatgg
    28501 ctggattatg tcgtcaatta aaaatgcggc gagtagatta gcaaatatcc acgctttcgc
    28561 gagttcaggt tcctttgcac gcaaagcatc caggtgcagc aaacttttga gccgcttaaa
    28621 agccagttca atttgccatc gcagacggta acaatcagcc acttgctctg ctgaatattc
    28681 atcttccggt aatgatgtta gcaatagcac atggcccgct gcttccagcg tttccgcctg
    28741 aactactcgt ccttttcgac gattctcgct gagcagtcgg gttttactga ttaatgcttt
    28801 ttcgggagga agtgatacgg caatgagacg tgccggaaag ggagctccgg cttttttatt
    28861 acctgaattg cctatcatta cagtggtttc accgttctta ccgcaatcca gcccgcgcag
    28921 aaaacccatc atgtcaaagc gcattccttc tgcagttaac cagcgcaatc ctcgccagtg
    28981 aacccggacg atataatcag cttctccaaa agcaagtgag cggatacatt cgggacgcga
    29041 accgaatccc cggtcagcaa tgcgtatctc gtctgccgtt tgcgcaaatc ggtccagccg
    29101 ttcagcgtct ctgctgtcgg ttagctcaaa atcagtgaac tgacaggtat gaggatcata
    29161 tcccatatgt agtcgccatt cagcgctgcc gcccccgggc gcactgattg ctgttccatc
    29221 gacaagacgc aatctctttc cgcttgtaca acccgtaact gcggcgcgta cagcaagtgt
    29281 ttgtgcggca agtatgccaa accagtcggc ggcattccgc agccgcttca ggagagccac
    29341 gtcagataat gttgcaacgt catggagctg agcccatgca gtgacttcac gtaatgacat
    29401 ccccccgggg ccgtaagcca gccccagacg tagcagagtt gcagcatcac gaatttcgcg
    29461 gcggcgggtt agagccccgg cattacgtgc cgaagtatcc agttcttcgg gcttaccaat
    29521 atgggccaga attgctgacc agttatcgtg agagtaattc atcggcacgt taaatcatat
    29581 caggcgtaat accacaaccc ttaagttagc gcttatggga ttactccccg cacaacggct
    29641 actttttcgg ttcgtaagcg agaacagcct taaactcaat attacgttcc ttcaccgtaa
    29701 actcacacag cgagtctccg accagaagcg taaatcccag caccgttaaa cacagcacta
    29761 tgactgccgc aagggcatat ttcgtcagca tgtttatatt gcctccatgc gaagaaggga
    29821 ctaccatcca aattgttcgg gtttggagtg gcagccccag ggttgataga aatatctcct
    29881 ggggcttcat ctttccagac ctcagagtaa acctgaaacc ggaaagcttc aggcacccgc
    29941 cgttatctta cccttcctca acaaaatagc tgtttattta tacagtgagt cctgtttcgg
    30001 acttctcact cctcatttaa tcaactgaag ctgaacccgt ttttttctgc atgactcaat
    30061 cgtcaaaatt cttcgccacc agtcagcact gccataactt gtcacattgc aaaagtagcc
    30121 aaattgcttc aggcaccatc agttcaccat caccaaaaaa aagaaacatt ccagaacttc
    30181 cgcatctcgc ccagccgctc cgacttctat actgaataga aaacgccaac ataagagaaa
    30241 cctatgccat tacccgattt tcatgtttct gaacctttta ccctcggtat tgaactggaa
    30301 atgcaggtgg ttaatccgcc gggctatgac ttaagccagg actcttcaat gctgattgac
    30361 gcggttaaaa ataagatcac ggccggagag gtaaagcacg atatcaccga aagtatgctg
    30421 gagctggcga cggatgtttg ccgtgatatc aaccaggctg ccgggcagtt ttcagcgatg
    30481 cagaaagtcg tattgcaggc agccacagac catcatctgg aaatttgcgg cggtggcacg
    30541 cacccgtttc agaaatggca gcgtcaggag gtatgcgata acgaacgcta tcaacgcacg
    30601 ctggaaaact ttggttatct cattcagcag gcgaccgttt ttggtcagca tgtccatgtt
    30661 ggctgcgcca gtggcgatga cgccatttat ttgctgcacg gcttgtcacg atttgtgccg
    30721 cactttatcg ccctttccgc cgcgtcgcca tatatgcagg gaacggatac gcgttttgcc
    30781 tcctcacgac cgaatatttt ttccgccttt cctgataatg gcccgatgcc gtgggtcagt
    30841 aactggcaac aatttgaagc cctgtttcgc tgtctgagtt acaccacgat gatcgacagc
    30901 attaaagatc tgcactggga tattcgcccc agtcctcatt ttggcacggt ggaggttcgg
    30961 gtgatggata ccccgttaac ccttagccac gcagtaaata tggcgggatt aattcaggct
    31021 accgcccact ggttactgac ggaacgcccg tttaaacatc aggaaaaaga ttacctgctg
    31081 tataaattca accgtttcca ggcctgtcgc tatgggcttg aaggcgtcat caccgatccg
    31141 cacactggag atcgtcgacc gctaacggaa gataccttgc gattgctgga aaaaatcgcc
    31201 ccttccgcac ataaaattgg tgcatcgagc gcgattgagg ccctgcatcg ccaggtcgtc
    31261 agcggtctga atgaagcgca gctaatgcgc gatttcgtcg ccgatggcgg ctcgctgatt
    31321 gggctggtga aaaagcattg tgagatctgg gccggtgact aagccgggaa ttgccttaca
    31381 gaagaatatc cctgacaatg gtgttttaac ttacatttaa caatgttatg aaacaccctt
    31441 tagaaacctt gaccaccgca gcaggcattt tgctgatggc tttcctctct tgc
//
LOCUS       DAPOAV010000049        31459 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.049, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000049 DAPOAV010000000
VERSION     DAPOAV010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31459
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.049"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..588
                     /gene="tuf"
                     /locus_tag="RN951_002567"
     CDS             <1..588
                     /gene="tuf"
                     /locus_tag="RN951_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312930.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDX2527549.1"
                     /translation="IPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEV
                     EIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKP
                     HTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKM
                     VVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLS"
     gene            818..1201
                     /gene="secE"
                     /locus_tag="RN951_002568"
     CDS             818..1201
                     /gene="secE"
                     /locus_tag="RN951_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007665874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HDX2527550.1"
                     /translation="MSANTEAQGSGRGLEAMKWVVVVALLLVAIVGNYLYRDIMLPLR
                     ALAVVILIAAAGGVALLTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTA
                     VMSLILWGLDGILVRLVSFITGLRF"
     gene            1203..1748
                     /gene="nusG"
                     /locus_tag="RN951_002569"
     CDS             1203..1748
                     /gene="nusG"
                     /locus_tag="RN951_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005280494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HDX2527551.1"
                     /translation="MSEAPKKRWYVVQAFSGFEGRVATSLREHIKLHNMEDLFGEVMV
                     PTEEVVEIRGGQRRKSERKFFPGYVLVQMVMNDASWHLVRSVPRVMGFIGGTSDRPAP
                     ISDKEVDAIMNRLQQVGDKPRPKTLFEPGEMVRVNDGPFADFNGVVEEVDYEKSRLKV
                     SVSIFGRATPVELDFSQVEKA"
     gene            1907..2335
                     /gene="rplK"
                     /locus_tag="RN951_002570"
     CDS             1907..2335
                     /gene="rplK"
                     /locus_tag="RN951_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006121495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HDX2527552.1"
                     /translation="MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNA
                     KTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKIS
                     RAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED"
     gene            2339..3043
                     /gene="rplA"
                     /locus_tag="RN951_002571"
     CDS             2339..3043
                     /gene="rplA"
                     /locus_tag="RN951_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HDX2527553.1"
                     /translation="MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFVESVDV
                     AVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAELVGMEDLAD
                     QIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQ
                     VRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPTQAKGVYIKKVSISTTM
                     GAGVAVDQAGLSASVN"
     gene            3456..3953
                     /gene="rplJ"
                     /locus_tag="RN951_002572"
     CDS             3456..3953
                     /gene="rplJ"
                     /locus_tag="RN951_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002438625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HDX2527554.1"
                     /translation="MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKA
                     GREAGVYMRVVRNTLLRRAVEGTPFECLKDAFVGPTLIAYSMEHPGAAARLFKEFAKA
                     NAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRD
                     AKEAA"
     gene            4020..4385
                     /gene="rplL"
                     /locus_tag="RN951_002573"
     CDS             4020..4385
                     /gene="rplL"
                     /locus_tag="RN951_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HDX2527555.1"
                     /translation="MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAG
                     PVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKD
                     DAEALKKALEEAGAEVEVK"
     gene            4705..8733
                     /gene="rpoB"
                     /locus_tag="RN951_002574"
     CDS             4705..8733
                     /gene="rpoB"
                     /locus_tag="RN951_002574"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004870488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDX2527556.1"
                     /translation="MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPE
                     GQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRL
                     VIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD
                     KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTE
                     QILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQ
                     LEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIE
                     TLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSE
                     DRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGN
                     RRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGS
                     SQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEG
                     PNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLD
                     EEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMG
                     ANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDE
                     MYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQ
                     NMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPN
                     VGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVK
                     DSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLF
                     SRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLE
                     AKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYD
                     ENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQ
                     RAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDL
                     PTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGK
                     AQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMP
                     ESFNVLLKEIRSLGINIELEDE"
     gene            8810..13033
                     /gene="rpoC"
                     /locus_tag="RN951_002575"
     CDS             8810..13033
                     /gene="rpoC"
                     /locus_tag="RN951_002575"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HDX2527557.1"
                     /translation="MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETI
                     NYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERM
                     GHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQIL
                     TEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLT
                     KRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRN
                     NRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGK
                     QGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLAT
                     TIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLH
                     PLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVL
                     GLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAK
                     TSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQI
                     MYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKV
                     IDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQL
                     AGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTR
                     RLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADI
                     LVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEA
                     IGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGK
                     LVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITE
                     VSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDV
                     LIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFE
                     ARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERV
                     ERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLR
                     KATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFI
                     SAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEA
                     PAAPQVTAEDASASLAELLNAGLGGSDNE"
     gene            13246..13785
                     /locus_tag="RN951_002576"
     CDS             13246..13785
                     /locus_tag="RN951_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-shock protein C"
                     /protein_id="HDX2527558.1"
                     /translation="MKQEVEKWRPFGHPDGDIRDLSFLDAHQAVYVQHHEGKEPLEYR
                     FWVTYSLHCFTKDYEHQTNEEKQSLMYHAPKESRPFCQHRYNLARTHLKRTILALPES
                     NVIHAGYGSYAVIEVDLDGGDKAFYFVAFRAFREKKKLRLHVTSAYPISEKQKGKSVK
                     FFTIAYNLLRNKQLPQPSK"
     gene            complement(14195..15328)
                     /gene="thiH"
                     /locus_tag="RN951_002577"
     CDS             complement(14195..15328)
                     /gene="thiH"
                     /locus_tag="RN951_002577"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HDX2527559.1"
                     /translation="MKTFSDRWRQLDWDDIRLRINGKTAADVERALNASQLTRDDMMA
                     LLSPAASGYLEQLAQRAQRLTRQRFGNTVSFYVPLYLSNLCANDCTYCGFSMSNRIKR
                     KTLDEADIARESAAIREMGFEHLLLVTGEHQAKVGMDYFRRHLPALREQFSSLQMEVQ
                     PLAETEYAELKQLGLDGVMVYQETYHEATYARHHLKGKKQDFFWRLETPDRLGRAGID
                     KIGLGALIGLSDNWRVDSYMVAEHLLWLQQHYWQSRYSVSFPRLRPCTGGIEPASIMD
                     ERQLVQTICAFRLLAPEIELSLSTRESPWFRDRVIPLAINNVSAFSKTQPGGYADNHP
                     ELEQFSPHDDRRPEAVAAALTAQGLQPVWKDWDSYLGRASQRL"
     gene            complement(15325..16095)
                     /gene="thiG"
                     /locus_tag="RN951_002578"
     CDS             complement(15325..16095)
                     /gene="thiG"
                     /locus_tag="RN951_002578"
                     /EC_number="2.8.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418418.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HDX2527560.1"
                     /translation="MLRIADKTFDSHLFTGTGKFASSQLMVEAIRASGSQLVTLAMKR
                     VDLRQHNDAILEPLIAAGVTLLPNTSGAKTAEEAIFAAHLAREALGTNWLKLEIHPDA
                     RWLLPDPIETLKAAETLVQQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQG
                     LETRAMLEIIIQQATVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVNMAK
                     AFRLAVEAGLLARQSGPGSRSYFAHATSPLTGFLEASA"
     gene            complement(16097..16297)
                     /gene="thiS"
                     /locus_tag="RN951_002579"
     CDS             complement(16097..16297)
                     /gene="thiS"
                     /locus_tag="RN951_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HDX2527561.1"
                     /translation="MQILFNDQAMQCAAGQTVHELLEQLDQRQAGAALAINQQIVPRE
                     QWAQHIVQDGDQILLFQVIAGG"
     gene            complement(16281..17036)
                     /gene="thiF"
                     /locus_tag="RN951_002580"
     CDS             complement(16281..17036)
                     /gene="thiF"
                     /locus_tag="RN951_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418420.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole biosynthesis adenylyltransferase ThiF"
                     /protein_id="HDX2527562.1"
                     /translation="MNDRDFMRYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAA
                     LYLAGAGVGTLVLADDDDVHLSNLQRQILFTTEDIDRPKSQVSQQRLTQLNPDIQLTA
                     LQQRLTGEALKDAVARADVVLDCTDNMATRQEINAACVALNTPLITASAVGFGGQLMV
                     LTPPWEQGCYRCLWPDNQEPERNCRTAGVVGPVVGVMGTLQALEAIKLLSGIETPAGE
                     LRLFDGKSSQWRSLALRRASGCPVCGGSNADPV"
     gene            complement(17029..17664)
                     /gene="thiE"
                     /locus_tag="RN951_002581"
     CDS             complement(17029..17664)
                     /gene="thiE"
                     /locus_tag="RN951_002581"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDX2527563.1"
                     /translation="MYQPDFPPVPFRSGLYPVVDSVQWIERLLDAGVRTLQLRIKDRR
                     DEEVEADVVAAIALGRRYNARLFINDYWRLAIKHQAYGVHLGQEDLQATDLNAIRAAG
                     LRLGVSTHDDMEIDVALAARPSYIALGHVFPTQTKQMPSAPQGLEQLARHVERLADYP
                     TVAIGGISLARAPAVIATGVGSIAVVSAITQAADWRLATAQLLEIAGVGDE"
     gene            complement(17664..19559)
                     /gene="thiC"
                     /locus_tag="RN951_002582"
     CDS             complement(17664..19559)
                     /gene="thiC"
                     /locus_tag="RN951_002582"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HDX2527564.1"
                     /translation="MSATKLTRREQRARAQHFIDTLEGTAFPNSKRIYITGTHPGVRV
                     PMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWID
                     ARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITP
                     EMEFIAIRENMGRERIRSEVLRHQHPGMSFGAHLPENITAEFVRDEVAAGRAIIPANI
                     NHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYI
                     HETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHA
                     GVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSL
                     GDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEE
                     LEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKE
                     DVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYH
                     DETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEI
                     YLRKEEA"
     regulatory      complement(19640..19740)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(19792..20268)
                     /gene="rsd"
                     /locus_tag="RN951_002583"
     CDS             complement(19792..20268)
                     /gene="rsd"
                     /locus_tag="RN951_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma D regulator"
                     /protein_id="HDX2527565.1"
                     /translation="MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLVGIKPGKE
                     SYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLARAAKIWPQLEANTQQ
                     IMDYYDSSLETAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLVLDAARVKHPA"
     gene            20363..21136
                     /gene="nudC"
                     /locus_tag="RN951_002584"
     CDS             20363..21136
                     /gene="nudC"
                     /locus_tag="RN951_002584"
                     /EC_number="3.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) diphosphatase"
                     /protein_id="HDX2527566.1"
                     /translation="MDRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRAL
                     QIGEWQGEPVWLVQQQRRHDMGSVRQVIDLDVGLFQLAGRGVQLAEFYRSHKYCGYCG
                     HEMYPSKTEWAMLCSHCRERYYPQIAPCIIVAIRRDDSILLAQHTRHRNGVHTVLAGF
                     VEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPK
                     ELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYE"
     gene            21176..22240
                     /gene="hemE"
                     /locus_tag="RN951_002585"
     CDS             21176..22240
                     /gene="hemE"
                     /locus_tag="RN951_002585"
                     /EC_number="4.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HDX2527567.1"
                     /translation="MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAG
                     DFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFTSP
                     VTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGS
                     SKAFTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQAVMIFDTWGGVLTGRD
                     YQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIA
                     DARRRVGNKVALQGNMDPSMLYAPPARIEEEVATILAGFGHGEGHVFNLGHGIHQDVP
                     PEHAGVFVEAVHRLSEQYHR"
     gene            22250..22921
                     /gene="nfi"
                     /locus_tag="RN951_002586"
     CDS             22250..22921
                     /gene="nfi"
                     /locus_tag="RN951_002586"
                     /EC_number="3.1.21.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease V"
                     /protein_id="HDX2527568.1"
                     /translation="MDLASLRAQQIELASSVIREDRLDKDPPDLIAGADVGFEQGGEV
                     TRAAMVLLKYPSLELVEYKVARIATTMPYIPGFLSFREYPALLAAWEMLSQKPDLVFV
                     DGHGISHPRRLGVASHFGLLVDVPTIGVAKKRLCGKFEPLSSEPGALAPLMDKGEQLA
                     WVWRSKARCNPLFIATGHRVSVDSALAWVQRCMKGYRLPEPTRWADAVASERPAFVRY
                     TANQP"
     gene            22964..23554
                     /locus_tag="RN951_002587"
     CDS             22964..23554
                     /locus_tag="RN951_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjaG family protein"
                     /protein_id="HDX2527569.1"
                     /translation="MLQNPIHLRLERLESWQHVTFMACLCERMYPNYAMFCQQTGFGD
                     GQIYRRILDLIWETLTVKDAKVNFDSQLEKFEEAIPSADDFDLYGVYPAIDACVALSE
                     LVHSRLSGETLEHAVEVSKTSITTVAMLEMTQAGREMSDEELKENPAVEQEWDIQWEI
                     FRLLAECEERDIELIKGLRADLREAGESNIGIIFQQ"
     gene            23741..24013
                     /gene="hupA"
                     /locus_tag="RN951_002588"
     CDS             23741..24013
                     /gene="hupA"
                     /locus_tag="RN951_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017460010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-alpha"
                     /protein_id="HDX2527570.1"
                     /translation="MNKTQLIDVIAEKAELSKTQAKAALESTLAAITESLKEGDAVQL
                     VGFGTFKVNHRAERTGRNPQTGKEIKIAAANVPAFVSGKALKDAVK"
     gene            24026..24721
                     /locus_tag="RN951_002589"
     CDS             24026..24721
                     /locus_tag="RN951_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1481 domain-containing protein"
                     /protein_id="HDX2527571.1"
                     /translation="MNSFNEGVVSPLLSFWRRSLMLAGALLLTACSHNSSLPPFTASG
                     FAEDQGAVRIWRKDSGDNVHLLAVFSPWRSGDTTTREYRWQGDNLTLININVYSKPPV
                     NIRARFDDRGDLSFMQRESDGEKQQLSNDQIDLYRYRADQIRQISDALRQGRVVLRQG
                     RWHAMEQTVTTCEGQTIKPDLDSQAIAHIERRQSRSSVDVSVAWLEAPEGSQLLLVAN
                     SDFCRWQPNEKTF"
     gene            complement(24723..25148)
                     /gene="zraP"
                     /locus_tag="RN951_002590"
     CDS             complement(24723..25148)
                     /gene="zraP"
                     /locus_tag="RN951_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc resistance sensor/chaperone ZraP"
                     /protein_id="HDX2527572.1"
                     /translation="MKRNTKIALVMMALSAMAMGSTSAFAHGGHGMWQQNAAPLTSEQ
                     QTAWQKIHNDFYAQSSALQQQLVTKRYEYNALLAANPPDSSKINAVAKEMENLRQSLD
                     ELRVKRDIAMAEAGIPRGAGMGMGYGGCGGGGHMGMGHW"
     gene            25386..26783
                     /gene="zraS"
                     /locus_tag="RN951_002591"
     CDS             25386..26783
                     /gene="zraS"
                     /locus_tag="RN951_002591"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     ZraS"
                     /protein_id="HDX2527573.1"
                     /translation="MRFMQRSKDSLAKWLSAILPVVIVGLVGLFAVTVIRDYGRASEA
                     DRQALLEKGNVLIRALESGSRVGMGMRMHHVQQQALLEEMAGQPGVLWFAVTDAQGII
                     ILHSDPDKVGRALYSPDEMQKLKPEENSRWRLLGKTETTPALEVYRLFQPMSAPWRHG
                     MHNMPRCNGKAVPQVDAQQAIFIAVDASDLVATQSGEKRNTLIILFALATVLLASVLS
                     FFWYRRYLRSRQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPA
                     GGEAHQLAQVMAKEADRLNRVVSELLELVKPTHLALQAVDLNTLINHSLQLVSQDANS
                     REIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKIS
                     VTDSGKGIAADQLDAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGSTF
                     TLWLPVNITRKDPQG"
     gene            26780..28105
                     /gene="zraR"
                     /locus_tag="RN951_002592"
     CDS             26780..28105
                     /gene="zraR"
                     /locus_tag="RN951_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent response regulator
                     transcription factor ZraR"
                     /protein_id="HDX2527574.1"
                     /translation="MTHDNIDILVVDDDISHCTILQALLRGWGYNVALANSGRQALEQ
                     VREQVFDLVLCDVRMAEMDGIATLKEIKALNPAIPVLIMTAYSSVETAVEALKTGALD
                     YLIKPLDFDNLQATLEKALAHTHSIDAETPAVTASQFGMVGKSPAMQHLLSEIALVAP
                     SEATVLIHGDSGTGKELVARAIHASSARSEKPLVTLNCAALNESLLESELFGHEKGAF
                     TGADKRREGRFVEADGGTLFLDEIGDISPMMQVRLLRAIQEREVQRVGSNQIISVDVR
                     LIAATHRDLAAEVNAGRFRQDLYYRLNVVAIEVPSLRQRREDIPLLAGHFLQRFAERN
                     RKAVKGFTPQAMDLLIHYDWPGNIRELENAVERAVVLLTGEYISERELPLAIASTPIP
                     LGQSQDIQPLVEVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR"
     gene            complement(28102..29391)
                     /gene="purD"
                     /locus_tag="RN951_002593"
     CDS             complement(28102..29391)
                     /gene="purD"
                     /locus_tag="RN951_002593"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HDX2527575.1"
                     /translation="MKVLVIGNGGREHALAWKAAQSPLVETVFVAPGNAGTALEPALQ
                     NVAIGVTDIPALLDFAQNEKIDLTIVGPEAPLVKGVVDTFRAAGLKIFGPTAGAAQLE
                     GSKAFTKDFLARHKIPTAEYQNFTEVEPALAYLREKGAPIVIKADGLAAGKGVIVAMT
                     LEEAEAAVHDMLAGNAFGDAGHRIVIEEFLDGEEASFIVMVDGEHVLPMATSQDHKRV
                     GDKDTGPNTGGMGAYSPAPVVTDDVHQRTMERIIWPTVKGMAAEGNTYTGFLYAGLMI
                     DKQGNPKVIEFNCRFGDPETQPIMLRMKSDLVELCLAACESKLDEKTSEWDERASLGV
                     VMAAGGYPGDYRTGDVIHGLPLEEVAGGKVFHAGTKLADDEQVVTNGGRVLCVTALGH
                     TVAEAQKRAYALMTDIHWDDCFCRKDIGWRAIEREQN"
     gene            complement(29403..30992)
                     /gene="purH"
                     /locus_tag="RN951_002594"
     CDS             complement(29403..30992)
                     /gene="purH"
                     /locus_tag="RN951_002594"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HDX2527576.1"
                     /translation="MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLL
                     AEKGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMEEHQIQPIDMVV
                     VNLYPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEM
                     DDNEGSLTLATRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNL
                     NFIKKLDMRYGENSHQQAAFYIEENVKEASVATATQVQGKALSYNNIADTDAALECVK
                     EFAEPACVIVKHANPCGVAIGNSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAI
                     ISRQFVEVIIAPSASEEALKITAAKQNVRVLTCGQWGERVPGLDFKRVNGGLLVQDRD
                     LGMVGAEELRVVTKRQPSEQELRDALFCWKVAKFVKSNAIVYAKNNMTIGIGAGQMSR
                     VYSAKIAGIKAADEGLEVKGSSMASDAFFPFRDGIDAAAAAGVTCVIQPGGSIRDDEV
                     IAAADEHGIAMLFTDMRHFRH"
BASE COUNT         7422 a         8148 c         8608 g         7281 t
ORIGIN      
        1 attccggaac cagagcgtgc gattgacaag ccgttcctgc tgccgatcga agacgtattc
       61 tccatctccg gtcgtggtac cgttgttacc ggtcgtgtag aacgcggtat catcaaagtt
      121 ggtgaagaag ttgaaatcgt tggtatcaaa gagactcaga agtctacctg tactggcgtt
      181 gaaatgttcc gcaaactgct ggacgaaggc cgtgctggtg agaacgtagg tgttctgctg
      241 cgtggtatca aacgtgaaga aatcgaacgt ggtcaggtac tggctaagcc gggcaccatc
      301 aagccgcaca ccaagttcga atctgaagtg tacattctgt ccaaagatga aggcggccgt
      361 catactccgt tcttcaaagg ctaccgtccg cagttctact tccgtactac tgacgtgact
      421 ggtaccatcg aactgccgga aggcgtagag atggtaatgc cgggcgacaa catcaaaatg
      481 gttgttaccc tgatccaccc gatcgcgatg gacgacggtc tgcgtttcgc aatccgtgaa
      541 ggcggccgta ccgttggcgc gggcgttgta gcaaaagttc tgagctaatt gccgataaca
      601 tttgacgcaa tgcgcactaa aagggcatca tttgatgccc tttttgcacg ctttcgtacc
      661 agaacctggc tcatcagtga ttttctttgt cataatcatt gctgagacag gctctgttga
      721 gggcgtataa tccgaaaagc taatacgcgt ttcgatttgg tttgcctcgc gatcgcgggg
      781 tgaaaatgtt tgtagaaaac ttctgacagg ttggtttatg agtgcgaata ccgaagctca
      841 aggaagcggg cgcggcctgg aagcgatgaa gtgggtcgtt gtggtggcat tgctcctggt
      901 ggcgattgtc ggcaactatc tttatcgcga cattatgctg ccgctgcgtg cgctggccgt
      961 agtaattctg attgctgcag cgggtggtgt cgcgctgtta acgacaaaag gtaaagctac
     1021 cgttgctttt gcccgtgaag cgcgtaccga agtccgtaag gtcatttggc cgactcgcca
     1081 ggaaacattg cacaccacgc tgattgtggc tgcggttacc gcagtaatgt cactgatcct
     1141 gtggggactg gatggtattc tggttcgcct ggtatccttt atcactggcc tgaggttctg
     1201 agatgtctga agctcctaaa aagcgctggt acgtcgttca ggcgttttcc ggttttgaag
     1261 gccgcgtagc aacgtcgctg cgtgagcata tcaaattaca caacatggaa gatttgtttg
     1321 gtgaagtcat ggtaccaacc gaagaagtgg ttgaaatccg tggcggtcag cgtcgcaaaa
     1381 gcgaacgtaa attcttccct ggctacgtcc tcgttcagat ggtgatgaac gacgcgagct
     1441 ggcacctggt gcgcagcgta ccgcgtgtga tgggcttcat cggcggtact tccgatcgtc
     1501 ctgcgccaat cagcgataaa gaagtcgatg cgattatgaa ccgcctgcag caggttggtg
     1561 ataagccgcg tccgaaaacg ctgtttgaac cgggtgaaat ggtccgtgtt aatgatggtc
     1621 cgttcgctga cttcaacggt gttgttgaag aagtggatta cgagaaatct cgtctgaaag
     1681 tgtctgtttc tatcttcggt cgtgcgaccc cggtagagct ggacttcagc caggttgaaa
     1741 aagcctaacc cagcgatcaa aaaagcggcg atttaatcgt tgcacaaggc gtgagattgg
     1801 aatacaattt cgcgcctttt gtttttatgg gccttgcccg taaaacgatt ttttatatca
     1861 cggggagcct ctcagaggcg ttattaccca acttgaggaa tttataatgg ctaagaaagt
     1921 acaagcctat gtcaagctgc aggttgcagc tggtatggct aacccgagtc cgccagtagg
     1981 tccggctctg ggtcagcagg gcgtaaacat catggaattc tgcaaagcgt tcaacgcaaa
     2041 aactgattcc atcgaaaaag gtctgccgat tccggtagta atcaccgttt acgctgaccg
     2101 ttctttcact ttcgttacca agaccccgcc ggcagcagtt ctgctgaaaa aagcggctgg
     2161 tatcaagtct ggttccggta agccgaacaa agacaaagtg ggtaaaattt cccgcgctca
     2221 gctgcaggaa atcgcgcaga ccaaagctgc cgacatgact ggtgccgaca ttgaagcgat
     2281 gactcgctcc atcgaaggta ctgcacgttc catgggcctg gtagtggagg actaagaaat
     2341 ggctaaactg accaagcgca tgcgtgttat ccgcgagaaa gttgatgcaa ccaaacagta
     2401 cgacatcaac gaagctatcg cactgctgaa agagctggcg actgctaaat tcgtagaaag
     2461 cgtggacgta gctgttaacc tcggcatcga cgctcgtaaa tctgaccaga acgtacgtgg
     2521 tgcaactgta ctgccgcacg gtactggccg ttccgttcgc gtagccgtat ttacccaagg
     2581 tgcaaacgct gaagctgcta aagctgcagg cgcagaactg gtaggtatgg aagatctggc
     2641 tgaccagatc aagaaaggcg aaatgaactt tgacgttgtt attgcttctc cggatgcaat
     2701 gcgcgttgtt ggccagctgg gccaggttct gggtccgcgc ggcctgatgc caaacccgaa
     2761 agtgggtact gtaacaccga acgttgctga agcggttaaa aacgctaaag ctggccaggt
     2821 tcgttaccgt aacgacaaaa acggcatcat ccacaccacc atcggtaaag tggactttga
     2881 cgctgacaaa ctgaaagaaa acctggaagc tctgctggtt gcgctgaaaa aagcaaaacc
     2941 gactcaggcg aaaggcgtgt acatcaagaa agttagcatc tccaccacca tgggtgcagg
     3001 tgttgcagtt gaccaggctg gcctgagcgc ttctgtaaac taatgccttt acgtgggcgg
     3061 tgattttgtc tacaatctta cccccacgta taatgcttaa tgcagacgta tatccgagat
     3121 attcgggttg tggcaaggcg gcaactgagt gagtcgccag gagcatagct aactatgtga
     3181 ctggtgcgaa tgaaggaagc caacgccgtc acaagctgaa tagcgacgga tagaaaagat
     3241 ttgttcgttg gagcctggcc tatccaggcc tccgtcgaag accgcaggag tttcgcaaga
     3301 aacttaatcc cctgcgtaga cggtgacaga acgctaagat tattctttta tattctggct
     3361 tgtttctgct caccgtaatt aagacgctct ctccgtttgg aggagtgaag tgagttccag
     3421 agattttctc tggcaaacat ccaggagcaa agctaatggc tttaaatctt caagacaaac
     3481 aagcgattgt tgctgaagtc agcgaagtag ccaaaggcgc gctgtctgca gtagttgcgg
     3541 attcccgtgg cgtaactgta gataaaatga ctgaactgcg taaagcaggt cgcgaagctg
     3601 gcgtatacat gcgtgttgtt cgtaacaccc tgctgcgccg tgctgttgaa ggtactccgt
     3661 tcgagtgcct gaaagacgcg tttgttggtc cgaccctgat tgcatactct atggaacacc
     3721 cgggcgctgc tgctcgtctg ttcaaagagt tcgcgaaagc gaatgcaaaa tttgaggtca
     3781 aagccgctgc ctttgaaggt gagctgatcc cggcgtctca gatcgaccgc ctggcaactc
     3841 tgccgaccta cgaagaagca attgcacgcc tgatggcaac catgaaagaa gcttcggctg
     3901 gcaaactggt tcgtactctg gctgctgtac gcgatgcgaa agaagctgct taatcgcagt
     3961 tatcttttta acgcattcgc ttacgtataa acttattctg atattcagga acaatttaaa
     4021 tgtctatcac taaagatcaa atcattgaag cagttgcagc tatgtctgta atggacgttg
     4081 tagaactgat ctctgcaatg gaagaaaaat tcggtgtttc cgctgctgct gctgtagctg
     4141 tagctgctgg cccggttgaa gctgctgaag aaaaaactga attcgacgta attctgaaag
     4201 ctgctggcgc taacaaagtt gctgttatca aagcagtacg tggcgcaact ggcctgggtc
     4261 tgaaagaagc taaagacctg gtagaatctg caccggctgc tctgaaagaa ggcgtgagca
     4321 aagacgacgc agaagcactg aaaaaagctc tggaagaagc tggcgctgaa gttgaagtta
     4381 aataagccaa cccttccggt tgcagcctga gaaatcaggc tgatggctgg tgacttttta
     4441 gtcaccagcc tttttgcgct gtaaggcgcc agtagcgttt cacactgttt gactactgct
     4501 gtgcctttca atgcttgttt ctatcgacga cttaatatac tgcgacagga cgtccgttct
     4561 gtgtaaatcg caatgaaatg gtttaagcgt gatagcaaca ggcattgcgg aaagtgttcc
     4621 attttccggt caacaaaata gtgttgcaca aactgtccgc tcaatggaca gatgggtcga
     4681 cttgtcagcg agctgaggaa ccctatggtt tactcctata ccgagaaaaa acgtattcgt
     4741 aaggattttg gtaaacgtcc acaagttctg gatgtacctt atctcctttc tatccagctt
     4801 gactcgtttc agaaatttat cgagcaagat cctgaagggc agtatggtct ggaagctgct
     4861 ttccgttccg tattcccgat tcagagctac agcggtaatt ccgagctgca atacgtcagc
     4921 taccgccttg gcgaaccggt gtttgacgtc caggaatgtc aaatccgtgg cgtgacctat
     4981 tccgcaccgc tgcgcgttaa actgcgtctg gtgatctatg agcgcgaagc gccggaaggc
     5041 accgtaaaag acattaaaga acaagaagtc tacatgggcg aaattccgct catgacagac
     5101 aacggtacct ttgttatcaa cggtactgag cgtgttatcg tttcccagct gcaccgtagt
     5161 ccgggcgtct tctttgactc cgacaaaggt aaaacccact cttcgggtaa agtgctgtat
     5221 aacgcgcgta tcatccctta ccgtggttcc tggctggact tcgaattcga tccgaaggac
     5281 aacctgttcg tacgtatcga ccgtcgccgt aaactgcctg cgaccatcat tctgcgcgcc
     5341 ctgaactaca ccacagagca gatcctcgac ctgttctttg aaaaagttat ctttgaaatc
     5401 cgtgataaca agctgcagat ggaactggtg ccggaacgcc tgcgtggtga aaccgcatct
     5461 tttgacatcg aagctaacgg taaagtgtac gtagaaaaag gccgccgtat cactgcgcgc
     5521 cacattcgcc agctggaaaa agacgacgtc aaactgatcg aagtcccggt tgagtacatc
     5581 gcaggtaaag tggttgctaa agactatatt gatgagtcta ccggcgagct gatctgcgca
     5641 gcgaacatgg agctgagcct ggatctgctg gctaagctga gccagtctgg tcacaagcgt
     5701 atcgaaacgc tgttcaccaa cgatctggat cacggcccat atatctctga aaccttacgt
     5761 gtcgacccaa ctaacgaccg tctgagcgca ctggtagaaa tctaccgcat gatgcgccct
     5821 ggcgagccgc cgactcgtga agcagctgaa agcctgttcg agaacctgtt cttctccgaa
     5881 gaccgttatg acttgtctgc ggttggtcgt atgaagttca accgttctct gctgcgcgaa
     5941 gaaatcgaag gttccggtat cctgagcaaa gacgacatca ttgatgttat gaaaaagctc
     6001 atcgatatcc gtaacggtaa aggcgaagtc gatgatatcg accacctcgg caaccgtcgt
     6061 atccgttccg ttggcgaaat ggcggaaaac cagttccgcg ttggcctggt acgtgtagag
     6121 cgtgcggtga aagagcgtct gtctctgggc gatctggata ccctgatgcc acaggatatg
     6181 atcaacgcca agccgatttc cgcagcagtg aaagagttct tcggttccag ccagctgtct
     6241 cagtttatgg accagaacaa cccgctgtct gagattacgc acaaacgtcg tatctccgca
     6301 ctcggcccag gcggtctgac ccgtgaacgt gcaggcttcg aagttcgaga cgtacacccg
     6361 actcactacg gtcgcgtatg tccaatcgaa acccctgaag gtccgaacat cggtctgatc
     6421 aactctctgt ccgtgtacgc acagactaac gaatacggct tccttgagac tccgtatcgt
     6481 aaagtgaccg acggtgttgt aactgacgaa attcactacc tgtctgctat cgaagaaggc
     6541 aactacgtta tcgcccaggc gaactccaac ttggatgaag aaggccactt cgtagaagac
     6601 ctggtaactt gccgtagcaa aggcgaatcc agcttgttca gccgcgacca ggttgactac
     6661 atggacgtat ccacccagca ggtggtatcc gtcggtgcgt ccctgatccc gttcctggaa
     6721 cacgatgacg ccaaccgtgc attgatgggt gcgaacatgc aacgtcaggc cgttccgact
     6781 ctgcgcgctg ataagccgct ggttggtact ggtatggaac gtgctgttgc cgttgactcc
     6841 ggtgtaactg cggtagctaa acgtggtggt gtcgttcagt acgtggatgc ttcccgtatc
     6901 gttatcaaag ttaacgaaga cgagatgtat ccgggtgaag caggtatcga catctacaac
     6961 ctgaccaaat acacccgttc taaccagaac acctgtatca accagatgcc gtgtgtgtct
     7021 ctgggtgaac cggttgaacg tggcgacgtg ctggcagacg gtccgtccac cgacctcggt
     7081 gaactggcgc ttggtcagaa catgcgcgta gcgttcatgc cgtggaatgg ttacaacttc
     7141 gaagactcca tcctcgtatc cgagcgtgtt gttcaggaag accgtttcac caccatccac
     7201 attcaggaac tggcgtgtgt gtcccgtgac accaagctgg gtccggaaga gatcaccgct
     7261 gacatcccga acgtgggtga agctgcgctc tccaaactgg atgaatccgg tatcgtttac
     7321 attggtgcgg aagtgaccgg tggcgacatt ctggttggta aggtaacgcc gaaaggtgaa
     7381 actcagctga ccccagaaga aaaactgctg cgtgcgatct tcggtgagaa agcctctgac
     7441 gttaaagact cttctctgcg cgtaccaaac ggtgtatccg gtacggttat cgacgttcag
     7501 gtctttactc gcgatggcgt agaaaaagac aaacgtgcgc tggaaatcga agaaatgcag
     7561 ctcaaacagg cgaagaaaga cctgtctgaa gaactgcaga tcctcgaagc gggtctgttc
     7621 agccgtatcc gtgctgtgct ggtagccggt ggcgttgaag ctgagaagct cgacaaactg
     7681 ccgcgcgatc gctggctgga gctgggcctg acagacgaag agaaacaaaa tcagctggaa
     7741 cagctggctg agcagtatga cgaactgaaa cacgagttcg agaagaaact cgaagcgaaa
     7801 cgccgcaaaa tcacccaggg cgacgatctg gcaccgggcg tgctgaagat tgttaaggta
     7861 tatctggcgg ttaaacgccg tatccagcct ggtgacaaga tggcaggtcg tcacggtaac
     7921 aagggtgtaa tttctaagat caacccgatc gaagatatgc cttacgatga aaacggtacg
     7981 ccggtagaca tcgtactgaa cccgctgggc gtaccgtctc gtatgaacat cggtcagatc
     8041 ctcgaaaccc acctgggtat ggctgcgaaa ggtatcggcg acaagatcaa cgccatgctg
     8101 aaacagcagc aagaagtcgc gaaactgcgc gaattcatcc agcgtgcgta cgatctgggc
     8161 gctgacgttc gtcagaaagt tgacctgagt accttcagcg atgaagaagt tatgcgtctg
     8221 gctgaaaacc tgcgcaaagg tatgccaatc gcaacgccgg tgttcgacgg tgcgaaagaa
     8281 gcagaaatta aagagctgct gaaacttggc gacctgccga cttccggtca gatccgcctg
     8341 tacgatggtc gcactggtga acagttcgag cgtccggtaa ccgttggtta catgtacatg
     8401 ctgaaactga accacctggt cgacgacaag atgcacgcgc gttccaccgg ttcttacagc
     8461 ctggttactc agcagccgct gggtggtaag gcacagttcg gtggtcagcg tttcggggag
     8521 atggaagtgt gggcgctgga agcatacggc gcagcataca ccctgcagga aatgctcacc
     8581 gttaagtctg atgacgtgaa cggtcgtacc aagatgtata aaaacatcgt ggacggcaac
     8641 catcagatgg agccgggcat gccagaatcc ttcaacgtat tgttgaaaga gattcgttcg
     8701 ctgggtatca acatcgaact ggaagacgag taattctcgc tcaaacaggt cactgctgtc
     8761 gggttaaaac ccggcagcgg attgtgctaa ctccgacggg agcaaatccg tgaaagattt
     8821 attaaagttt ctgaaagcgc agactaaaac cgaagagttt gatgcgatca aaattgctct
     8881 ggcttcgcca gacatgatcc gttcatggtc tttcggtgaa gttaaaaagc cggaaaccat
     8941 caactaccgt acgttcaaac cagaacgtga cggccttttc tgcgcccgta tctttgggcc
     9001 ggtaaaagat tacgagtgcc tgtgcggtaa gtacaagcgc ctgaaacacc gtggcgtcat
     9061 ctgtgagaag tgcggcgttg aagtgaccca gactaaagta cgccgtgagc gtatgggcca
     9121 catcgaactg gcttccccga ctgcgcacat ctggttcctg aaatcgctgc cgtcccgtat
     9181 cggtctgctg ctcgatatgc cgctgcgcga tatcgaacgc gtactgtact ttgaatccta
     9241 tgtggttatc gaaggcggta tgaccaacct ggaacgtcag cagatcctga ctgaagagca
     9301 gtatctggac gcgctggaag agttcggtga cgaattcgac gcgaagatgg gggcggaagc
     9361 aatccaggct ctgctgaaga gcatggatct ggagcaagag tgcgaacagc tgcgtgaaga
     9421 gctgaacgaa accaactccg aaaccaagcg taaaaagctg accaagcgta tcaaactgct
     9481 ggaagcgttc gttcagtctg gtaacaaacc agagtggatg atcctgaccg ttctgccggt
     9541 actgccgcca gatctgcgtc cgctggttcc gctggatggt ggtcgtttcg cgacttctga
     9601 cctgaacgat ctgtatcgtc gcgtcattaa ccgtaacaac cgtctgaaac gtctgctgga
     9661 tctggctgcg ccggacatca tcgtacgtaa cgaaaaacgt atgctgcagg aagcggtaga
     9721 cgccctgctg gataacggtc gtcgcggtcg tgcgatcacc ggttctaaca agcgtcctct
     9781 gaaatctttg gccgacatga tcaaaggtaa acagggtcgt ttccgtcaga acctgctcgg
     9841 taagcgtgtt gactactccg gtcgttctgt aatcaccgta ggtccatacc tgcgtctgca
     9901 tcagtgcggt ctgccgaaga aaatggcact ggagctgttc aaaccgttca tctacggcaa
     9961 gctggaactg cgtggtcttg ctaccaccat taaagctgcg aagaaaatgg ttgagcgcga
    10021 agaagctgtc gtttgggata tcctggacga agttatccgc gaacacccgg tactgctgaa
    10081 ccgtgcaccg actctgcacc gtctgggtat ccaggcattt gaaccggtac tgatcgaagg
    10141 taaagctatc cagctgcacc cgctggtttg tgcggcatat aacgccgact tcgatggtga
    10201 ccagatggct gttcacgtac cgctgacgct ggaagcccag ctggaagcgc gtgcgctgat
    10261 gatgtctacc aacaacatcc tgtccccggc gaacggcgaa ccaatcatcg ttccgtctca
    10321 ggacgttgta ctgggtctgt actacatgac ccgtgactgt gttaacgcca aaggcgaagg
    10381 catggtgctg actggcccga aagaagcaga acgtctgtat cgctctggtc tggcttctct
    10441 gcatgcgcgc gttaaagtgc gtatcaccga gtatgaaaaa gatgctaacg gtgaattagt
    10501 agcgaaaacc agcctgaaag acacgactgt tggccgtgcc attctgtgga tgattgtacc
    10561 gaaaggtctg ccttactcca tcgtcaacca ggcgctgggt aaaaaagcaa tctccaaaat
    10621 gctgaacacc tgctaccgca ttctcggtct gaaaccgacc gttatttttg cggaccagat
    10681 catgtacacc ggcttcgcct atgcagcgcg ttctggtgca tctgttggta tcgatgacat
    10741 ggtcatcccg gagaagaaac acgaaatcat ctccgaggca gaagcagaag ttgctgaaat
    10801 tcaggagcag ttccagtctg gtctggtaac tgcgggcgaa cgctacaaca aagttatcga
    10861 tatctgggct gcggcgaacg atcgtgtatc caaagcgatg atggataacc tgcaaactga
    10921 aaccgtgatt aaccgtgacg gtcaggaaga gaagcaggtt tccttcaaca gcatctacat
    10981 gatggccgac tccggtgcgc gtggttctgc ggcacagatt cgtcagcttg ctggtatgcg
    11041 tggtctgatg gcgaagccgg atggctccat catcgaaacg ccaatcaccg cgaacttccg
    11101 tgaaggtctg aacgtactcc agtacttcat ctccacccac ggtgctcgta aaggtctggc
    11161 ggataccgca ctgaaaactg cgaactccgg ttacctgact cgtcgtctgg ttgacgtggc
    11221 gcaggacctg gtggttaccg aagacgattg tggtacccat gaaggtatca tgatgactcc
    11281 ggttatcgag ggtggtgacg ttaaagagcc gctgcgcgat cgcgtactgg gtcgtgtaac
    11341 tgctgaagac gttctgaagc cgggtactgc tgatatcctc gttccgcgca acacgctgct
    11401 gcacgaacag tggtgtgacc tgctggaaga gaactctgtc gacgcggtta aagtacgttc
    11461 tgttgtatct tgtgacaccg actttggtgt atgtgcgcac tgctacggtc gtgacctggc
    11521 gcgtggccac atcatcaaca agggtgaagc aatcggtgtt atcgcggcac agtccatcgg
    11581 tgaaccgggt acacagctga ccatgcgtac gttccacatc ggtggtgcgg catctcgtgc
    11641 ggctgctgaa tccagcatcc aagtgaaaaa caaaggtagc atcaagctca gcaacgtgaa
    11701 gtcggttgtg aactccagcg gtaaactggt tatcacttcc cgtaatactg aactgaaact
    11761 gatcgacgaa ttcggtcgta ctaaagaaag ctacaaagta ccttacggtg cggtactggc
    11821 gaaaggcgat ggcgaacagg ttgctggcgg cgaaaccgtt gcaaactggg acccgcacac
    11881 catgccggtt atcaccgaag taagcggttt tgtacgcttt actgacatga tcgacggcca
    11941 gaccattacg cgtcagaccg acgaactgac cggtctgtct tcgctggtgg ttctggattc
    12001 cgcagaacgt accgcaggtg gtaaagatct gcgtccggca ctgaaaatcg ttgatgctca
    12061 gggtaacgac gttctgatcc caggtaccga tatgccagcg cagtacttcc tgccgggtaa
    12121 agcgattgtt cagctggaag atggcgtaca gatcagctct ggtgacaccc tggcgcgtat
    12181 tccgcaggaa tccggcggta ccaaggacat caccggtggt ctgccgcgcg ttgcggacct
    12241 gttcgaagca cgtcgtccga aagagccggc aatcctggct gaaatcagcg gtatcgtttc
    12301 cttcggtaaa gaaaccaaag gtaaacgtcg tctggttatc accccggtag acggtagcga
    12361 tccgtacgaa gagatgattc cgaaatggcg tcagctcaac gtgttcgaag gtgaacgtgt
    12421 agaacgtggt gacgtaattt ccgacggtcc ggaagcgccg cacgacattc tgcgtctgcg
    12481 tggtgttcat gctgttactc gttacatcgt taacgaagta caggacgtat accgtctgca
    12541 gggcgttaag attaacgata aacacatcga agttatcgtt cgtcagatgc tgcgtaaagc
    12601 taccatcgtt aacgcgggta gctccgactt cctggaaggc gaacaggttg aatactctcg
    12661 cgtcaagatc gcaaaccgcg aactggaagc gaacggcaaa gtgggtgcaa cttactcccg
    12721 cgatctgctg ggtatcacca aagcgtctct ggcaaccgag tccttcatct ccgcggcatc
    12781 gttccaggag accactcgcg tgctgaccga agcagccgtt gcgggcaaac gcgacgaact
    12841 gcgcggcctg aaagagaacg ttatcgtggg tcgtctgatc ccggcaggta ccggttacgc
    12901 gtaccaccag gatcgtatgc gtcgccgtgc tgcgggtgaa gctccggctg caccgcaggt
    12961 gactgcagaa gacgcatctg ccagcctggc agaactgctg aacgcaggtc tgggcggttc
    13021 tgataacgag taatcgttaa tccgcaaata acgtaaaaac ccgcttcggc gggttttttt
    13081 atggggggag tttagggaaa gagcatttgt cagaatattt aaggaatttc tgaatactca
    13141 taatcaatgt agagatgact aatatcctga aactgactga actaattgag tcaaactcgg
    13201 caaggattcg atactattcc tgtgtaactt tcttaaggaa cgagaatgaa acaggaagtg
    13261 gaaaagtggc gaccttttgg acatccggat ggtgatattc gtgatttatc atttcttgat
    13321 gctcatcagg ctgtctacgt tcagcatcat gagggcaaag agcctttaga gtatcgcttt
    13381 tgggttacct actctcttca ctgcttcaca aaagattatg aacatcagac gaacgaagaa
    13441 aaacaatcgt taatgtacca cgcgcctaaa gaatctcgtc ccttctgcca gcaccgttat
    13501 aacttagcgc gcacacactt aaaaagaact attttggcgc tgccagaaag caacgttatt
    13561 catgccgggt atggtagcta tgccgtgatt gaggtggact tagacggagg agataaggca
    13621 ttttactttg ttgcgttcag ggctttcagg gaaaagaaaa aactccgttt gcatgtaact
    13681 agcgcttatc ccatttctga aaaacagaaa ggtaaatcag tgaaattttt caccattgcc
    13741 tacaacttat tgagaaataa gcagcttcct cagccctcaa aataacaaaa cccaccttaa
    13801 ggtgggtttc gccagagaat tatctctggt attcagaacg ccattaccgg actttgcctt
    13861 gaccttgcga taatcgcagg ttgcgggatg tctgaatttc ttcagtctgc tgcatcctgg
    13921 aagatgagaa catgtgttct tattttcgtc tctatcatag ttgagtattt actctcttac
    13981 aatcagatct ctttcattgc tcaacaggcg atggcttcag actttgcatt acggaatttt
    14041 taagaaaggc agggcgaaac gaggaagaag cttttcgccc tggacaacat tcctgctgac
    14101 ggcactacca taaaaaaaca caacgctttc aacaaccttg cgtttttcat cttccgtagc
    14161 ggctcggaat aaatttacgt tcttacattc cgtctcatag tctttgcgag gcgcgtccca
    14221 gatagctgtc ccagtctttc cataccggct gcaaaccctg agcggttaac gcggcagcaa
    14281 ccgcttccgg tctgcgatcg tcgtgcggtg agaactgttc caactcgggg tgattatcgg
    14341 catagccacc tggctgcgtt ttcgagaagg cgctgacgtt attgatcgcc agcggaataa
    14401 cgcgatcgcg aaaccacggt gattcccgcg tggagagtga cagttcaatc tccggtgcaa
    14461 gcagtcggaa ggcgcagatg gtttgcacta actggcgttc atccataatc gacgcaggct
    14521 caatgccgcc agtacacggg cgcaggcgcg gaaaggagac agagtaacgg ctttgccagt
    14581 aatgctgttg cagccatagc aaatgttcgg caaccatata gctgtcaacg cgccagttgt
    14641 cggaaaggcc aattagcgcg ccgaggccta tcttatcaat ccccgcacgc cccagccgat
    14701 ccggcgtttc cagccgccag aagaagtcct gttttttgcc tttcagatga tggcgggcat
    14761 aagtcgcctc gtgatatgtc tcctgataaa ccatcacgcc atccagacca agttgcttta
    14821 actcggcgta ttccgtctcc gccagcggtt gcacttccat ctgtagtgaa gagaactgtt
    14881 cacgaagggc agggagatga cgacgaaagt aatccatccc cactttcgcc tgatgttcac
    14941 cagtgactaa cagcagatgt tcaaagccca tctcccgtat agcggcactt tccctagcaa
    15001 tatccgcttc atccagcgtt ttgcgcttga tgcgattact catggaaaat ccacagtacg
    15061 tgcagtcgtt agcgcaaaga ttggaaagat aaagcgggac gtagaaacta actgtgttgc
    15121 caaatcgctg acgggtcaga cgctgcgccc gttgggccag ttgttccaga tagccactgg
    15181 cggcaggcga taacagcgcc atcatgtcgt cgcgggtgag ttgcgaggca tttagcgccc
    15241 gctctacgtc agcagccgtt ttgccgttga tacgcaggcg gatgtcgtcc cagtccagtt
    15301 gtcgccagcg atcgctgaag gttttcatgc cgatgcctcc agaaatccgg tcagcgggct
    15361 ggtggcatga gcaaaataac tgcggctgcc cggtccggac tgacgtgcca gtaggcctgc
    15421 ttctaccgcc agacgaaatg ccttcgccat gttgacggga tcgtccgcga cggcaatcgc
    15481 cgtattcact aacaccgcgt cggcccccat ttccagcgcc tgcgcggcat ggctgggaac
    15541 gccgatgcca gcatcgacaa ccaccggcac tgtggcctgc tggataataa tctccagcat
    15601 ggcgcgggtt tccagtccct gattcgagcc aatcggcgcg ccgagcggca tcaccgctgc
    15661 acagccgact tcttccagac gtttacacaa taccggatcg gccccgcagt aaggcagcac
    15721 gacaaatccc tgttgtacca gcgtttcggc ggctttcagg gtttcgatgg gatcgggcaa
    15781 cagccagcgg gcgtcagggt gaatctctaa ttttaaccag tttgtgccta acgcttcacg
    15841 agccagatgg gcggcgaaaa tggcttcttc cgctgttttc gccccggatg tatttggcag
    15901 cagggtcaca cccgccgcga taagcggttc gaggatagcg tcgttgtgct ggcgcaagtc
    15961 gacacgtttc atcgccagtg tcaccagctg gctgccggaa gcgcggatcg cctccaccat
    16021 cagttgtgaa gaagcgaatt tccctgtgcc ggtaaacaga tgtgaatcaa acgttttgtc
    16081 cgcaatacgt aacatttcaa ccccctgcaa taacctgaaa aagcaggatc tggtcgccat
    16141 cctgcacgat atgttgcgcc cactgctcac gcgggacgat ttgctgatta atcgccagag
    16201 ccgcgcccgc ttgtcgttgg tcgagttgct ccagtagttc gtgaacagtt tgcccggcgg
    16261 cgcactgcat cgcttgatcg ttaaacagga tctgcattgc ttcctccgca taccgggcaa
    16321 ccactggcgc ggcgcaacgc caggctgcgc cactggctcg atttaccgtc gaacagtcgg
    16381 agttctcccg caggtgtctc tataccgctt aataacttaa tggcttccag tgcctgcaaa
    16441 gtgcccataa ccccgaccac cgggccaacc acgcccgccg tgcggcagtt gcgttctggc
    16501 tcctggttat ctggccacag gcagcggtaa cacccctgct cccagggcgg cgtcagtacc
    16561 atcaactgac cgccaaatcc gaccgcgctg gcggtgataa gcggcgtgtt gagtgccacg
    16621 caggcggcat taatctcctg gcgagtcgcc atattgtcgg tacagtcgag caccacatcg
    16681 gcccgtgcaa ccgcatcttt taacgcctca cccgttaacc gttgttgtaa tgctgtcagt
    16741 tgaatgtcgg gattcaactg tgtcagtcgc tgttggctga cctgcgattt cgggcgatcg
    16801 atatcttcag tggtaaagag gatttgtcgt tgcagattgc ttaaatgcac atcgtcgtca
    16861 tctgccagta ccagcgtccc gacgccagcg cccgccaggt acagcgcagc aggtgtaccc
    16921 agcccgccca gaccgataat cagcacctgg ctgtcgagca gtttttgctg cccgtccaga
    16981 gcgatatcgt cgagcaggat ttggcggcta taacgcataa agtcacggtc attcatcgcc
    17041 aactcctgca atttccagca actgtgccgt tgccaaacgc cagtctgcgg cttgagtaat
    17101 ggcgctgacg acggcgatac tgccgacacc cgttgctatc accgcaggcg cgcgtgccag
    17161 actgataccg ccaatcgcca cggtgggata atccgccagt cgctcaacat gccgtgccag
    17221 ctgttccagc ccctgcggtg cagaaggcat ctgtttggtt tgcgtcggga acacatgtcc
    17281 cagcgcgata taagaggggc gtgctgccag cgcgacgtcg atttccatat cgtcatgtgt
    17341 cgaaacgccc agccgcaggc ctgccgcgcg gatggcattg agatcggtgg cttgcaaatc
    17401 ttcctgcccc aaatggacgc catacgcctg atgcttgatc gccagccgcc agtaatcgtt
    17461 gataaacaat cgcgcgttat agcggcggcc cagcgcaatt gccgccacga catcggcttc
    17521 cacctcttca tcgcgccgat ctttgatgcg tagctggaga gtacgtacgc ctgcatccaa
    17581 cagacgttcg atccactgta cgctgtccac caccgggtac agtcctgaac gaaaaggtac
    17641 aggaggaaaa tcaggctgat acatcacgct tcctccttac gcaggtagat ttctccgcct
    17701 ctggcacgga agttctccga catatccgcc attcccattt caatagtttg cgtggcggcg
    17761 taatcacgca cttcctggct gattttcatc gagcagaatt tcggcccaca catggagcaa
    17821 aaatgggcga ctttacctga ctcttgcggc agggtttcat cgtgataagc gcgggcggta
    17881 aacgggtcga gggccagatt aaactggtct tcccagcgaa attcgaagcg ggctttcgac
    17941 atggcgttat cgcgaatttg cgcgcccgga tgccctttcg ccaggtcagc ggcgtgggcg
    18001 gcaatcttat aggtgataag cccctgctta acatcttctt tattgggcag acccagatgc
    18061 tcttttggcg ttacgtaaca gagcatcgcg cagccaaacc agccaatcat cgccgcacca
    18121 atccccgacg tgaagtggtc atagcccggc gcaatatcgg tagttagcgg ccccagagtg
    18181 taaaacggcg cttcgtggca gtgctctaac tcctcggtca tattgcggcg gatcatctgc
    18241 atcggcacgt ggcctgggcc ttcaatcatc acctgcacgt catattccca ggcaattttg
    18301 gtcagttcgc ccagcgtatg cagctcggca aactgcgctt catcgttggc gtcctgaata
    18361 gaaccggggc gcagaccgtc gcccagcgac agcgaaacgt cataagcggc acagatttca
    18421 caaatttcgc ggaagtgttg atagaggaaa ttttcctgat gatgggagag gcaccatttc
    18481 gccataatcg aaccgccgcg agagacgata ccggtcaggc gtttcgcggt catcggcaca
    18541 tagcgcagca gtacgcccgc atggatagtg aagtaatcca caccttgctc ggcctgttcc
    18601 agcagcgtgt cgcggaacgc ttcccaggta agatcttcgg cgatcccgtt aaccttctcc
    18661 agcgcctggt agatcggcac tgtaccgatc ggcaccgggc tgttacgcaa aatccactcg
    18721 cgggtttcgt gaatatagcg accggtggag agatccatca ccgtatccgc tccccagcgc
    18781 gtggaccata ccagcttttc cacttcttct tcgatggaag aggtgaccgc cgagttgccg
    18841 atattggcgt taacttttac caggaaattg cgaccaataa tcatcggctc cgattccgga
    18901 tgattaatgt tggccgggat aatcgcacgt ccggcagcaa cttcatcacg gacaaattcc
    18961 gcagtgatat tttccggcag atgtgcgcca aagctcattc ccggatgctg gtggcgtaaa
    19021 acctcgctac ggatgcgctc gcggcccata ttctcgcgga tggcgatgaa ttccatttcc
    19081 ggcgtgatga tgccctggcg ggcgtagtgc agttgggtga cacggcgtcc tgctttggcg
    19141 cgttttggtg ttagtacgcc gctaaaacgc agttcgtcga ggccatcatc tgccagccgc
    19201 gctttagtgt aatcggaact gcgcacggta agttcttcgg tatcgccgcg cgcatcgatc
    19261 cacggctggc gtagttttgc cagcccttgc tgcacgttaa tggcaatctg cggatcacca
    19321 tacgggccgg aggtgtcgta gaccggaatc gcttcgtttt cttcgtactg cggctgttct
    19381 ttgctaccgc caattagcgt cgggctaagc tggatctcac gcatcggcac gcgcacgccg
    19441 gggtgtgtgc cagtgatata aatgcgtttt gagttgggaa aggcggtgcc ttccagggtg
    19501 tcgataaaat gttgggcccg ggcgcgttgt tcgcggcggg tcagttttgt tgcagacata
    19561 gctcattcca aaaagttaag gacgtggctt gtcagacgac ggatgaagca agagacgatc
    19621 gccgcagggg cgatgcgata gcagattaac tcttgttccc ttcgcaggta ttagcctgat
    19681 caggttccgc ggatcccgaa taaacggtct cagccagtta aggcactccg acaagaaatt
    19741 agccccgcaa atggggcatt gaatgtaaat tacgcgttaa cagcgcagaa ctcaagcagg
    19801 atgtttgacg cgggcggcgt caagcaccag cagaatcagc ttatcttcca gcacaaagcg
    19861 cgcttccagc gcctcgccga tgtcagataa aacctgttga aactcaaggt aattatcatg
    19921 atcgatggcg gtttccagac tggaatcgta gtaatccata atctgttgag tattggcttc
    19981 gagttgcggc caaatcttcg cggcgcgcgc gagttgcccg ttgccttcca gcttatgaag
    20041 aatgcgctca taaatactga aatgtccggc agacaagtaa tcgaccaggc tctgacaaaa
    20101 atcatcaagg gctttttcgt ttagcctcat gtacgattct ttgccaggct taatgccaac
    20161 cagattgtag taagccacga gcagatgctt acgtacatgt agccagcgat caaccagttt
    20221 gttacttcct ctgacgcgct ccgtcaggtt atcgagctgg ttaagcatga ttgactccgc
    20281 aagtttgtat tcaaaaactg ctcagtgaga aatgtaaaaa ccatgttaaa catgccagtg
    20341 atgcaaaggt agtgcaagag ctatggatcg tataattgaa aaattagatc acggctggtg
    20401 ggtcgtcagc catgaacaaa aattatggtt gccgaaggga gaattgccat atggcgaagc
    20461 ggcaaatttc gatcttgtgg gtcagcgcgc actacaaatc ggcgaatggc agggggaacc
    20521 tgtttggtta gtacaacagc agcggcgtca cgatatgggg tcggtacgtc aggtcattga
    20581 tctcgatgtt gggctgtttc aactggccgg acgaggcgta caactggcgg agttttaccg
    20641 atcgcataaa tactgtggtt actgcgggca tgaaatgtat ccgagcaaaa ccgaatgggc
    20701 gatgctgtgc agccattgcc gtgagcgtta ctacccgcaa atcgccccct gcattattgt
    20761 tgccatccgt cgcgatgatt cgatcctcct cgcccagcat acccgccatc gtaacggtgt
    20821 ccatacagta cttgccggat tcgtcgaagt gggcgaaacc ctcgagcagg cagtcgcgcg
    20881 ggaagtgatg gaagagagcg gaattaaagt taaaaacttg cgttacgtga cttctcagcc
    20941 gtggccgttt cctcagtctt taatgaccgc gtttatggcg gaatatgaca gcggcgacat
    21001 cgtgatcgac ccgaaagaat tgctcgaggc gaactggtat cgctatgacg atttgccgtt
    21061 actcccgccg cccggcaccg tagcgcgccg tctgatagaa gatacggtgg cgatgtgtcg
    21121 ggcagagtat gagtgatgat acactgaccg cctgacgcac taaggaacag ccaaaatgac
    21181 cgaacttaaa aacgatcgtt atctgcgggc gctgctgcgc cagcccgttg atgtcactcc
    21241 agtatggatg atgcgccagg cgggtcgcta tctaccggaa tataaagcca cgcgcgccca
    21301 ggcaggcgat tttatgtcgc tgtgcaaaaa cgccgagctg gcgtgcgaag tgactttgca
    21361 accgctgcgt cgctacccgc tggatgcggc gatcctcttt tccgatatcc tcaccgtgcc
    21421 ggacgcgatg gggttagggc tctattttga agccggagaa ggtccgcgtt ttacctcgcc
    21481 agtcacctgc aaagctgacg tcgataaact gccaattccg gacccggaag atgaactggg
    21541 ttacgtgatg aacgcggtgc gtaccattcg tcgcgaactg aaaggcgaag tgccgctgat
    21601 tggtttttcc ggcagcccgt ggacgctggc gacctacatg gtggaaggcg gcagcagcaa
    21661 agccttcacc gtgatcaaaa aaatgatgta tgccgatccg caggcgctgc acgctctgct
    21721 cgataaactg gcgaaaagcg tcactttgta tctgaatgcg cagattaaag ccggtgctca
    21781 ggcagtgatg attttcgaca cctggggcgg cgtgcttacc gggcgcgatt atcaacagtt
    21841 ctcgctctat tacatgcata aaattgttga tggtttactg cgtgaaaacg acggtcgccg
    21901 cgtaccggtc acgctgttta ccaaaggcgg cggacagtgg ctggaagcca tggcagaaac
    21961 cggttgcgat gcgctgggcc tcgactggac aacggacatc gccgatgcgc gccgccgtgt
    22021 gggcaataaa gtcgcgttgc agggtaatat ggatccgtcg atgctgtacg cgccgcctgc
    22081 ccgcattgaa gaagaagtag cgactatact tgcaggtttc ggtcacggcg aaggtcatgt
    22141 ctttaacctt ggtcacggca ttcatcagga tgtgccgcca gaacatgctg gcgtgttcgt
    22201 ggaggcagtg catcgactgt ctgaacagta tcaccgctaa ggagtgatta tggatctcgc
    22261 gtcattacgc gctcaacaaa tcgaactggc ttcttctgtg atccgcgagg atcgactcga
    22321 taaagatcca ccggatctga tcgccggagc cgatgtcggg tttgagcagg gcggagaagt
    22381 gacgcgagcg gcgatggtgc tgctgaaata tccctcgctt gagctggtcg agtataaagt
    22441 tgcccgcatc gccaccacca tgccttacat tccaggtttt ctttccttcc gcgaatatcc
    22501 tgcgctgctg gcagcgtggg agatgctgtc gcaaaagccg gatttagtgt ttgtcgatgg
    22561 tcatgggatc tcgcatcctc gccgtcttgg cgtcgccagc cattttggct tattggtgga
    22621 tgtgccgacc attggcgtgg cgaaaaaacg gctctgcggt aaattcgaac cgctctccag
    22681 cgaaccgggc gcgctggccc cactgatgga taaaggcgag cagctggcct gggtctggcg
    22741 cagcaaagcg cgctgtaacc cgttgtttat cgctaccggc catcgggtca gcgtggacag
    22801 cgcgctggcg tgggtacaac gctgcatgaa aggctatcgt ctgccggagc caacgcgctg
    22861 ggcggacgcg gtggcctcgg aacgtccggc gttcgtgcgc tatacagcaa atcagcccta
    22921 attcaggtaa actgcggata atttccgtat ttgagaactc aacatgttac aaaacccaat
    22981 tcatctgcgt ctggagcgcc tggaaagctg gcagcatgtc actttcatgg cttgcttatg
    23041 cgaacgcatg taccccaatt acgccatgtt ctgccagcaa accggttttg gtgatgggca
    23101 aatttaccgt cgcattctcg atctcatctg ggaaacgctg accgttaaag acgcaaaagt
    23161 aaatttcgac agccaactgg agaaatttga agaagcgatt ccttcagccg acgatttcga
    23221 tctgtacggc gtttatccgg caatcgatgc ctgcgtggcg ttaagtgaac tggtccattc
    23281 gcgtttgagt ggtgaaacgc tcgaacacgc ggtggaagtg agtaagacct ccatcacgac
    23341 cgttgcgatg ctggaaatga ctcaggctgg tcgcgaaatg agcgatgaag agcttaaaga
    23401 aaacccagct gtagagcaag aatgggacat tcagtgggaa atattccgac ttttagctga
    23461 gtgcgaagaa cgcgatatcg agctgataaa aggccttagg gcagacctgc gtgaggcggg
    23521 tgagagcaat attggtataa tttttcagca ataagaccag aaaacgtgat ttaacgcctg
    23581 atttgtcgta cctggagtct tccctttcgc cccccgtctg gtctacattt ggggggcgaa
    23641 aaaaagtggc tatcggtgcg tgtatgcagg agagtgctat tctggcattt ccgtcgcact
    23701 cgatgcttag caagcgataa acacattgta aggataactt atgaacaaga ctcaactgat
    23761 tgatgtaatt gcagagaaag cagaactgtc caaaacccag gctaaagctg ctctggagtc
    23821 cactctggct gcaattactg agtctctgaa agaaggcgat gctgtacaac tggttggttt
    23881 cggtaccttc aaagtgaacc accgcgctga gcgtactggc cgcaacccgc agaccggtaa
    23941 agaaatcaaa attgccgcag ctaacgtacc ggcatttgtt tctggcaagg cactgaaaga
    24001 cgcagttaag taagattgcg tggcagtgaa cagttttaac gaaggggtgg tttcacccct
    24061 tttgtctttc tggcgtcgat cattgatgct ggctggcgct ctgcttctca ctgcctgtag
    24121 tcataactct tcacttcctc cctttaccgc cagtggattt gctgaagacc agggcgcggt
    24181 acgcatctgg cgaaaagaca gcggcgataa tgtgcatctg cttgccgtgt ttagcccgtg
    24241 gcgcagtggc gataccacga cgcgagagta tcgctggcag ggcgataacc tcacgctcat
    24301 caatatcaat gtttacagca aaccgccggt gaatattcgc gcgcgttttg acgatcgcgg
    24361 tgatctgagc tttatgcaac gtgaatccga tggggaaaag cagcagcttt ctaacgacca
    24421 aatcgattta taccgttatc gtgctgatca gatccgccag attagcgatg ccttacgtca
    24481 ggggagagtc gtgctgcgcc aggggcgctg gcatgcgatg gaacagaccg tgaccacctg
    24541 cgaagggcaa accattaaac ctgatttaga ttcgcaggcg atagcgcata tcgagcgccg
    24601 ccagagccgc tcttctgttg atgtcagcgt ggcatggctg gaagcgcccg aaggttcgca
    24661 attactgtta gtggcaaact ctgatttctg tcgctggcaa cccaacgaga aaacgttctg
    24721 atttaccagt ggcccatacc catatgaccg ccaccaccgc agccgccgta gcccatgccc
    24781 attccggctc cgcgcggaat acccgcttca gccatcgcga tatctcgttt cacccgtaac
    24841 tcatctaacg actgacgcaa attctccatc tctttggcga ccgcgttaat tttgctgcta
    24901 tccggtgggt tcgcggctaa cagggcattg tattcataac gcttcgtcac cagttgctgt
    24961 tgcagtgcgc tgctttgagc gtaaaagtca ttatggattt tctgccacgc tgtctgttgt
    25021 tcgctggtca aaggcgcggc attttgctgc cacataccgt gtccgccgtg agcaaatgca
    25081 gatgtcgatc ccatcgccat tgctgaaagc gccatcatta ccagggcaat tttcgtgttc
    25141 cgtttcatgg ttaatcctcc agtggttgtc ttacttcggg tattgcatct tccgtgccaa
    25201 cgatgaaacg ctgatatgac gggtaatctg gcatgataaa cgagtaaaaa tgactcgcct
    25261 gctgcgggta gcgagtcatt tttactcatt gaaacttaag cctttgtgtt acagcgcagg
    25321 gtaagcgctg ataaaagatg gcatgatttc tgctgtcaga aagggatgag caggcaaaga
    25381 agaagatgcg ttttatgcaa cgttctaaag actccttagc taaatggtta agcgcgatcc
    25441 tccccgtggt cattgttggg ctggtgggat tgtttgcggt aactgtgatt cgtgattatg
    25501 ggcgggcaag cgaggcagac cgccaggcat tactggaaaa aggtaatgtg cttatccgcg
    25561 ctctggagtc gggaagccgc gtagggatgg ggatgcgaat gcaccatgta cagcaacagg
    25621 cgcttctgga agagatggcg ggacagccgg gagtgttgtg gttcgcagtc accgatgcgc
    25681 agggcatcat tattcttcat agcgaccccg ataaggtcgg gcgtgcgctc tattcgccgg
    25741 atgaaatgca gaaattaaag ccagaggaaa actcccgctg gcggctgctt gggaaaacgg
    25801 aaactacgcc tgcacttgag gtctatcgtt tgttccagcc aatgtcagcg ccctggcggc
    25861 atggaatgca caatatgccg cgctgtaacg gcaaagctgt gccacaagta gatgcacaac
    25921 aggctatttt tatcgccgtt gatgccagtg atctggttgc aacccagagt ggggaaaagc
    25981 gcaataccct gattatcctc ttcgccctgg cgacggtctt gctggcaagc gtattgtcat
    26041 tcttctggta tcgccgctat ctgcgctcgc gccagcttct acaagatgaa atgaagcgca
    26101 aagagaagct ggtggcgctg gggcatcttg cggcaggcgt tgcccacgaa atccgtaacc
    26161 cactttcctc gattaaagga ctggcgaaat actttgccga gcgcgcgcct gcagggggag
    26221 aagcgcatca actggcgcag gtgatggcga aagaggccga ccgtttaaac cgcgtggtaa
    26281 gcgagttgct ggaactggtt aagccaacgc atctggcttt gcaggcggtg gatctcaaca
    26341 cgctgattaa ccactcatta cagctggtaa gtcaggatgc aaacagccgg gagatccagt
    26401 tacgctttac cgccaacgac acattaccgg aaattcaggc cgacccggac aggctgactc
    26461 aggtcctgtt gaatctctat ctcaatgcta ttcaggcgat tggtcagcat ggcgtgatta
    26521 gcgtgacggc cagcgaaagc ggcgcgggcg tgaaaatcag cgttaccgac agcggtaagg
    26581 gaattgcggc agatcagctt gatgccatct tcactccgta cttcaccact aaagccgaag
    26641 gcaccggatt ggggctggcg gtcgtgcata atattgttga acaacacggt ggtacaattc
    26701 aggtcgcaag ccaggaggga aaaggctcaa cgttcaccct ctggcttccg gtcaatatta
    26761 cgcgtaagga cccacaagga tgacgcacga taatatcgat attctggtgg tggatgatga
    26821 cattagccac tgcactattt tgcaggcttt actgcgcggc tggggctata acgtcgcgct
    26881 ggcgaacagc gggcgacagg cgttggagca ggtgcgggaa caggtttttg atcttgtgct
    26941 ttgcgatgtg cgaatggcgg agatggacgg catcgccacg ctgaaagaga tcaaagcgtt
    27001 aaacccggca attccggtgc tgattatgac tgcgtactcc agcgtcgaga cggcggtaga
    27061 ggcactgaaa actggggcgc tggattatct catcaagccg ctggatttcg ataacctaca
    27121 ggcgacgctg gaaaaagcgc tcgcgcatac gcacagtatt gatgctgaaa cacctgcggt
    27181 gactgccagc cagttcggta tggtcggtaa aagcccggcg atgcaacacc tgctcagtga
    27241 aatcgccctc gtcgcgccat cggaagccac ggtactgatc cacggcgatt ccggcaccgg
    27301 taaagagctg gtcgccaggg cgattcacgc cagtagcgca cgtagcgaaa aaccgctggt
    27361 aacgctcaac tgtgcggcac tcaacgaatc cttgctggaa tctgaattgt tcggtcacga
    27421 aaaaggggcg tttactggag ccgataaacg ccgggaaggg cgctttgttg aggcggacgg
    27481 cggcacgctg tttctcgatg aaattggcga tatctcgccg atgatgcagg tgcgtctgct
    27541 gcgtgcgatt caggagcgcg aagttcagcg tgtcggtagc aaccagatta tctcggttga
    27601 tgtccggctg attgcggcga cccatcgcga tcttgccgca gaggtgaatg ccgggcgttt
    27661 tcgccaggat ctctactatc gcctgaatgt ggtggcgatt gaagtaccat cgctgcggca
    27721 acggcgggaa gatatccctc tgctggctgg ccattttctg cagcgctttg ccgagcgtaa
    27781 tcgcaaggcg gtaaaaggtt ttacgcccca ggcgatggat ctgttgattc attacgactg
    27841 gccgggaaat attcgtgagc tggaaaacgc ggtggaacgg gcagtggtgc tgctgaccgg
    27901 ggaatatatt tccgaacgcg agctgccgct ggcgattgcc agtacgccga tcccgctggg
    27961 acaaagtcag gatattcagc cgttggtgga agtggaaaaa gaggtgattc tggcggcgct
    28021 ggagaaaacg ggcggcaaca aaaccgaagc cgcccgtcag ttagggatca cgcgcaaaac
    28081 gctattggca aaactgtcgc gttagttctg ctcgcgttcg atagcgcgcc agccgatatc
    28141 tttccggcag aagcagtcgt cccagtggat atcggtcatt aaggcatagg cgcgtttctg
    28201 cgcttctgcc acggtatgac ccagcgcggt gacgcacagt acgcgcccgc cgttggtcac
    28261 tacctgctcg tcatccgcca gttttgtgcc cgcgtggaac actttgccgc ctgccacttc
    28321 ttccagcggc aggccgtgga tcacgtcacc ggtgcggtaa tcacccggat atccacccgc
    28381 agccatcacc acgccgagag aagcgcgttc atcccactcg gacgttttct cgtccagttt
    28441 gctttcacag gccgccaggc agagctcaac cagatcggac ttcatgcgca gcataatcgg
    28501 ctgggtttcc ggatcgccaa agcggcagtt aaattcaata accttcggat tgccctgttt
    28561 gtcgatcatc aggcccgcgt agagaaaacc ggtgtaggtg ttgccttccg ccgccatgcc
    28621 tttcacggtt ggccagataa tacgttccat ggtgcgctga tgaacgtcat cggttactac
    28681 cggcgcgggg gagtaagcgc ccatcccgcc ggtgtttggt ccggtatctt tatcgcctac
    28741 gcgtttgtga tcctggctgg tagccatcgg cagcacatgc tcgccgtcca ccatcacgat
    28801 aaagctcgct tcttcgccat cgaggaactc ttcgataacg atgcgatgac ccgcgtcgcc
    28861 aaaagcgttg cccgccagca tatcgtgaac agccgcttcc gcttcttcca gcgtcatcgc
    28921 cacgataacg cctttcccgg cagccagacc gtccgcttta atgacgattg gcgcgccttt
    28981 ctcacgcaga tacgccagcg caggttctac ctcggtgaag ttctggtatt ccgccgtagg
    29041 gatcttatgg cgggccagga aatctttggt aaacgctttt gagccttcca gttgggccgc
    29101 acctgcggtt gggccgaaga ttttcagccc ggcggcgcgg aaggtatcga ccacgccttt
    29161 caccagcggc gcttccgggc cgacgatggt cagatcaatc ttttcgtttt gtgcgaaatc
    29221 caacagcgcc gggatatcgg tcacgccaat agcaacgttt tgcagcgcgg gttccagtgc
    29281 agtgcctgca ttacccggag caacaaaaac agtctcaacc agcggcgact gggccgcttt
    29341 ccaggccagc gcgtgctcgc gcccgccgtt accaatcact aatactttca tctattgctc
    29401 cattaatggc ggaagtggcg catgtcggtg aagagcatcg caataccgtg ctcgtcggcg
    29461 gcggcaatca cttcgtcatc acggatagaa ccgccaggct ggattacgca ggtcacgccc
    29521 gcagcggcgg cggcatcaat accgtcgcgg aacgggaaga acgcgtcaga agccatcgag
    29581 gaacctttca cttccaggcc ttcatcggcc gctttaatac cggcgatttt tgcggagtac
    29641 acgcggctca tctggcccgc gccaatgccg atagtcatat tgtttttggc atagacgata
    29701 gcgttggatt tcacaaactt cgccaccttc cagcagaaca gcgcatcacg cagttcctgt
    29761 tcgctcggct gacgtttggt caccacgcgc agttcttccg caccgaccat ccccaggtca
    29821 cgatcctgaa ccagcagacc gccgttcacg cgtttgaaat cgaggcccgg aacacgctcg
    29881 ccccactgac cgcaggtcag aacgcgtacg ttctgtttgg cggcggtgat tttcagggct
    29941 tcttcgctgg cggacggcgc aataatcact tcgacaaact gacgagaaat gatggcctgt
    30001 gcggtttccg catccagctc gcggttaaag gcaatgatgc cgccgaatgc ggaggttggg
    30061 tcggttttgt acgcgcgatc gtaagcatca agaatggaat tgccgatagc cacgccgcaa
    30121 gggttggcgt gcttcacaat cacacatgcc ggctcggcga actctttcac gcactccagc
    30181 gccgcatcgg tatcggcgat gttgttataa gagagggctt taccctgaac ctgggttgcg
    30241 gtagcaacgg aggcttcttt cacattctct tctatataga aggcagcctg ctggtggctg
    30301 ttctcgccgt aacgcatatc cagcttctta atgaagttca ggttcagcgt gcgtgggaag
    30361 cgaccggcgg cttctttgct ttcaccgtgg taagccggaa ccatgctgcc gaagtagttg
    30421 gcaatcatgc tgtcgtaggc ggcagtgtgt tcgaaggctt tgatggcgag gtcgaaacgg
    30481 gttgcaagcg tcagcgatcc ttcgttgtca tccatctctt taataatggc gtcatagtcg
    30541 ctgctcttca ccacgattgc gacatcttta tggttcttgg cggcggagcg caccatcgtt
    30601 gggccgccga tatcgatgtt ctcaaccgca tcttccagcg agcaaccttc acgggccacg
    30661 gtctgggcga acggatacag gttaacaacc accatatcga taggctggat ctgatgttct
    30721 tccataatgg catcgtcctg gccgcgacgg cccagaatgc caccatgtac tttcggatgc
    30781 agggtcttca cgcgtccatc catcatctcc gggaaaccgg tgtaatcgga aacttcggtt
    30841 accggcagac ctttttctgc taacagacgg gcagtgcccc ctgtagacag cagctccaca
    30901 ccgcgtgcgg aaagtgcctg ggcgaattcg acgataccgg ctttgtcaga aacactgagc
    30961 agagcgcggc ggactggacg acgttgttgc atggtaaatc ccctggattt gactattaca
    31021 gagagcgtta gctgaatttt tcgcgaaaaa ctcagctaac gcccctaacg gggcatcctt
    31081 atttttcgcc cgcattgtaa cgaaaacgtt tgcgcaacgc tcgcgaattt ttctctttca
    31141 atggtgatca caattttgac tgtggttacc gtgggcaaaa tacagaaatt acattgatga
    31201 ttgtggataa ctctgtgcgt aaaaaggtat aaagcgggct tttgctgggg aatgcagcag
    31261 tcagtcattt ttctgcaatt tttctattgc ggcctgcgga gaactcccta taatgcgcct
    31321 ccatcgacac ggcggatgtg aatcacttca cacaaacagc cggttcggtt gaagagaaaa
    31381 atcctgaaat tcagggttga ctctgaaaga ggaaagcgta atatacgcca cctcgcgaca
    31441 gtgcgctaaa gcgcgtcgc
//
LOCUS       DAPOAV010000050        31107 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.050, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000050 DAPOAV010000000
VERSION     DAPOAV010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31107
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.050"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..4598
                     /locus_tag="RN951_002595"
     CDS             <1..4598
                     /locus_tag="RN951_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001335741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="autotransporter domain-containing protein"
                     /protein_id="HDX2527577.1"
                     /translation="DGDQAIVNNEGESTITNGGTGTQINGNDATANNSGKTTVDGKDS
                     TGTKIAGNIGIVNLDGSLTVTGGAHGVENIGDNGTVNNKGDIVVSDTGSIGVLINGEG
                     ATVSNTGDVNVSNEATGFSITTNSGKVSLAGSMQVGDFSTGVDLNGNNNSVTLAAKDL
                     KVVGQKATGINVSGDANTVNITGNVLVDKDKTADNAAEYFFDPSVGINVYGSDNNVTL
                     DGKLTVVSDSEVTSRQSNLFDGSAEKTSGLVVIGDGNTVNMNGGLELIGEKNALADGS
                     QVTSLRTGYSYTSVIVVSGESSVYLNGDTTISGEFPLGFAGVIRVQDKALLEIGSGAT
                     LTMQDIDSFEHHGTRTPELTYADSGAKIVNKGTVEIQNLGFAFVTGENTTGINSGTIS
                     LLQNGKDPAPSPIVLLATNGGSATNAGTITGKVTEQHSVFNKYSTGTSNSFIFNNDVS
                     SITGLVAQSNSTIINTDSGIIDLYGRGSVGMLAIADSTAENQGKITLDSMWVDANDTT
                     AMRDIASNSAIDFGTGVGVGTDSYSGAGKNATAINQLGGVITIYNAGAGMAAYGASNT
                     VINQGTINLEKNDNYDDSLAANTLVGMAVYEHGTAINDQTGVININVGTGQAFYNDGT
                     GTIVNYGTICTFGVCQSGNEYNNTDDFTSLIYTGGDTITRSGETVTLNKSAAVTDKLA
                     GNVVNSGTLSGDQITVSSGLLENTSGGIINNLVKLDKGAVIKNAGVMTNNVDVSGGIL
                     NNAGEMTAQITMNAGADSSLVNNTGTINKIVQNAGVFNNSGSVTGRMMSAGGVFNNQT
                     DGAIMRGAALTGTAVANNEGTWNLGSSSEGNNTGMLEVNNNSAFNNRGEFILDNDKNA
                     VHINQSGTLYNTGHMNISNSSHNGAVNMWGGNGRFINDGTIDVSAKSLVVSANNAGDQ
                     NAFFWNQDNGVINFDHDSASAVKVTHSNFIAQNDGIMNISGTGAVAMEGDKNAQLVNN
                     GTINLGTAGTTDTGMIGMQLDANATADAVIENNGTINIFANDSFAFSVLGTVGHVVNN
                     GTVVIADGVTGSGLIKQGDSINVEGMNGNNGNSSEVHYGDYTLPDVPKPNTVSVTSGS
                     DEAGGSMNNLNGYVVGTNVNGSAGKLKVNNASMNGVEINTGFTAGTADTTVSFDNVVE
                     GSNLTDADAITSTSVVWTAKGSTDASGNVDVTMSKNAYTDVATDASVNDIAKALDAGY
                     TNNELFTSLNVGTTAELNSALKQVSGSQATTVFREARVLSNRFSMLADAAPKVGNGLA
                     FNVVAKGDPRAELGNNTEYDMLALRKTIDLSESQTMSLEYGIARLDGDGAQKAGDNGV
                     TGGYSQFFGLKHQMSFDNGMNWNNALRYDVHNLDSSRSIAFGNTNKTADTDVKQQYLE
                     FRSEGAKTFEPSEGLKVTPYAGVKLRHTLEGGYQERNAGDFNLNMNSGSETAVDSIVG
                     LKLDYAGKDGWSASATLEGGPNLSYAKSQRTASLAGAGSQHFNVDDGQKGGGINSLTS
                     VGVKYSSKESSLNLDAYNWKEDGISDKGVMLNFKKTF"
     gene            4806..5666
                     /gene="pdxI"
                     /locus_tag="RN951_002596"
     CDS             4806..5666
                     /gene="pdxI"
                     /locus_tag="RN951_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 4-dehydrogenase"
                     /protein_id="HDX2527578.1"
                     /translation="MSSNTFTLGTKSVNRLGYGAMQLAGPGVFGPPRDRHVAITVLRE
                     ALALGVNHIDTSDFYGPHVTNQIIREALYPYSDDLTIVTKIGARRGEDASWLPAFSPA
                     ELQKAVHDNLRNLGLDVLDVVNLRVMMGDGHGPAEGSIEASLTVLAEMQQQGLVKHIG
                     LSNVTPTQVAEARKIAEIVCVQNEYNIAHRADDAMIDALAHDGIAYVPFFPLGGFTPL
                     QSSTLSDVAASLGATPMQVALAWLLQRSPNILLIPGTSSVAHLRENMAAEKLHLSEEV
                     LSTLDGISRE"
     gene            5729..8035
                     /locus_tag="RN951_002597"
     CDS             5729..8035
                     /locus_tag="RN951_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415925.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2773 domain-containing bactofilin"
                     /protein_id="HDX2527579.1"
                     /translation="MFKARNCGWIRLLPLFMLSLPVQAELRCVANAVDIESFFSAATA
                     EDKQQVEQAINSSVNLVPFGLSASNWKVHRGDLVVEGNIESNQKLIVLGNLTVKGNIS
                     TFSLSNPWVILGNVTATNIVADSPLLITGSINASGLVFIDSYYDNPSTIKGSINARGI
                     FINDIIAPVVASSTNSEFMVRASDKHDTENVKKALMIINPDAYYWGLINDEDALKEIF
                     KRSNIRMAGNVCNQMKKEALFRPKPSPELVQELQMLDEGKVAAFEGRDIATFDLAVMR
                     TLPRLKGISANLRKQLINSNDEQTIESMARYMPDNEILELTDQQLGYQPVVLGLLDRE
                     PLSVEIMTRMSRLPDGVGPLNLALRENLPLDIVMTLAKRDWDMIIQELYKDAWLLPES
                     IIDGYIRSDDSSIRQVGAGGQLTYNQAMQLANDSSNNVVTSLAFKLAEMKHHGQLLRM
                     TPQESDKVAGYLYQKFENDDDLIRVLFLALPDNLQFNFVKRMEKKSPAYFCCRDMQVI
                     HSDAALQRLLTRFNDPEGWSNLAKNQYLSTSMKQKIWQRALSHRKNNPKADSDAYETS
                     ADMILSELISHGEVDDQMLLNATALIRSDDWDFLESALISWDNLPAVVLKELQQNTPR
                     NDIWAKFFLRQENSSRAQVDEALRVYYALDPDALAQLDVLAKQPDRIWWSTLAKSNLT
                     FFKFGALNNRHTPPAVLAAEIDPEWWIVAMNNPRFPVDVLKARLKRDPLLALELVNPE
                     LDLVRQLALNGKTRAIREQAMRKLDELY"
     gene            8206..8811
                     /locus_tag="RN951_002598"
     CDS             8206..8811
                     /locus_tag="RN951_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415926.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HDX2527580.1"
                     /translation="MTLYQIKPLFQSLLRPTMFWLYKHHVTANHITLAALALSLLTGL
                     LLMLAAQPILFLLLPIVLFIRMALNALDGMLARECNQQTRLGAILNETGDVISDIALY
                     LPFLFLPESNASLVILMLFCTILTEFCGLLAQTINGVRSYAGPFGKSDRALIFGLWGL
                     AVAIYPQWMQWNNLLWSIASILLLWTAINRCRSVLLMSAEI"
     gene            8811..9707
                     /locus_tag="RN951_002599"
     CDS             8811..9707
                     /locus_tag="RN951_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDX2527581.1"
                     /translation="MLEKSLATLFALLILATLINRFLLWRLPERKGGEVTLRIRTWWG
                     IVICFSMVISGPRWMTLTFFALISFLALKEYCTLISVHFPRWLYWGIPLNYLLIGFNC
                     FELFLLFIPLAGFLILATGQVLVGDPSGFLHTVSAIFWGWIMTVFALSHAAWLLMLPT
                     TNIQGGALLVLFLLALTESNDIAQYLWGKSCGRRKVVPKVSPGKTLEGLMGGVITIMI
                     ASLIIGPLLTPLNTLQALLAGLLIGISGFCGDVVMSAIKRDIGVKDSGKLLPGHGGLL
                     DRIDSLIFTAPVFFYFIRYCCY"
     gene            9723..11480
                     /locus_tag="RN951_002600"
     CDS             9723..11480
                     /locus_tag="RN951_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional alpha/beta hydrolase/class I
                     SAM-dependent methyltransferase"
                     /protein_id="HDX2527582.1"
                     /translation="MENSRIPGEHFFTTSDNTALFYRHWPALQPGAKKVIVLFHRGHE
                     HSGRLQHLVDELAMPDTAFYAWDARGHGKSSGPRGYSPSLARSVRDVDEFVRFAASDS
                     QVGLEEVVVIAQSVGAVLVATWIHDYAPAIRGLVLASPAFKVKLYVPLARPALALWHR
                     LRGLFFINSYVKGRYLTHDRQRGASFNNDPLITRAIAVNILLDLYKTSERIIRDAAAI
                     TLPTQLLISGDDYVVHRQPQIDFYQRLRSPLKELHLLPGFYHDTLGEENRALAFEKMQ
                     SFISRLYANKSQKFDYQHEDCTGPSADRWRLLSGGPVPLSPVDLAYRFMRKAMKLFGT
                     HSSGLHLGMSTGFDSGSSLDYVYQNQPQGSNAFGRLVDKIYLNSVGWRGIRQRKTHLQ
                     ILIKQAVADLHAKGLAVRVVDIAAGHGRYVLDALANEPAVSDILLRDYSELNVAQGQE
                     MIAQRGMSGRVRFEQGDAFNPEELSALTPRPTLAIVSGLYELFPENEQVKNSLAGLAN
                     AIEPGGILIYTGQPWHPQLEMIAGVLTSHKDGKPWVMRVRSQGEMDSLVRDAGFDKCT
                     QRIDEWGIFTVSMAVRRDN"
     gene            11470..12786
                     /locus_tag="RN951_002601"
     CDS             11470..12786
                     /locus_tag="RN951_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310040.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2/dual specificity phosphatase
                     family protein"
                     /protein_id="HDX2527583.1"
                     /translation="MITERRNVLLQGAGWLLLLAPFFFFTYGSLNQFTAVQDLNSHDI
                     PSQVFGWETAIPFLPWTIVPYWSLDLLYGFSLFVCSTTFEQRRLVHRLILATVMACCG
                     FLLYPLKFSFIRPEVSGVTGWLFSQLELFDLPYNQSPSLHIILCWLLWRHFRQHLAER
                     WRKVCGGWFLLIAISTLTTWQHHFIDVITGLAVGMLIDWMVPVDRRWNYQKPDQRRIK
                     IALPYVVGAGSCIVLMELMMMIQLWWSVWLCWPVLSLLIIGRGYGGLGAITTGKDSQG
                     KLPPAVYWLTLPCRIGMWLSMRWFCRRLEPVSKMTAGVYLGAFPRHIPAQNAVLDVTF
                     EFPRGRATKDRLYFCVPMLDLVVPEEGELRQAVAMLETLREEQGSVLVHCALGLSRSA
                     LVVAAWLLCYGHCKTVNEAISYIRARRPQIVLTDEHKAMLRLWENR"
     gene            complement(12840..13445)
                     /gene="azoR"
                     /locus_tag="RN951_002602"
     CDS             complement(12840..13445)
                     /gene="azoR"
                     /locus_tag="RN951_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HDX2527584.1"
                     /translation="MSKVLVLKSSILAGYSQSNQLSDYFVEQWREKHSADEITVRDLA
                     ANPIPVLDGELVGALRPSDAPLTPRQQEALALSDELIAELKAHDVIVIAAPMYNFNIS
                     TQLKNYFDLVARAGVTFRYTENGPEGLVTGKKAIVITSRGGIHKDGPTDLVTPYLSTF
                     LGFIGITDVKFVFAEGIAYGPEMAAKAQSDAKAAIDSIVSA"
     gene            13646..17548
                     /gene="hrpA"
                     /locus_tag="RN951_002603"
     CDS             13646..17548
                     /gene="hrpA"
                     /locus_tag="RN951_002603"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415931.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase HrpA"
                     /protein_id="HDX2527585.1"
                     /translation="MTEQQKLTFTALQQRLDSLMLRDRLRFSRRLHGVKKVKNPDAQQ
                     AIFQEMAKEIDQAAGKVLLREAARPEITYPDNLPVSQKKQDILEAIRDHQVVIVAGET
                     GSGKTTQLPKICMELGRGIKGLIGHTQPRRLAARTVANRIAEELKTEPGGCIGYKVRF
                     SDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLKELLP
                     RRPDLKIIITSATIDPERFSRHFNNAPIIEVSGRTYPVEVRYRPIVEEADDTERDQLQ
                     AIFDAVDELSQESHGDILIFMSGEREIRDTADALNKLNLRHTEILPLYARLSNSEQNR
                     VFQSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQAS
                     ANQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAA
                     FPFVEAPDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLARMVLE
                     AQKHGCVREAMIITSALSIQDPRERPMDKQQASDEKHRRFHDKESDFLAFVNLWNYLG
                     EQQKALSSNAFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHI
                     ALLTGLLSHIGMKDADKQEYTGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGR
                     IAARIDPEWVEPVAQHLIKRTYSEPHWERAQGAVMATEKVTVYGLPIVAARKVNYSQI
                     DPALCRELFIRHALVEGDWQTRHAFFRENLKLRAEVEELEHKSRRRDILVDDETLFEF
                     YDQRISHDVISARHFDSWWKKVSRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGN
                     LKLRLSYQFEPGADADGVTVHIPLPLLNQVEESGFEWQIPGLRRELVIALIKSLPKPV
                     RRNFVPAPNYAEAFLGRVKPLELPLLDSLERELRRMTGVTVDREDWHWDQVPDHLKIT
                     FRVVDDKNKKLKEGRSLQDLKDALKGKVQETLSAVADDGIEQSGLHIWSFGQLPESYE
                     QKRGNYKVKAWPALVDERDSVAIKLFDNPLEQKQAMWNGLRRLLLLNIPSPIKYLHEK
                     LPNKAKLGLYFNPYGKVLELIDDCISCGVDKLIDANGGPVWTEEGFAALHEKVRAELN
                     DTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMGGLVYRGFVTGNGFK
                     RLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVENVQQAWQQWINKLPPARREDEDVK
                     EIRWMIEELRVSYFAQQLGTPYPISDKRILQAMEQISG"
     gene            17820..18620
                     /locus_tag="RN951_002604"
     CDS             17820..18620
                     /locus_tag="RN951_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDX2527586.1"
                     /translation="MNITPFPTLSPATIDAINVIGQWLAQDDFSGEVPYQADCVILAG
                     NAVMPTIDAACKIARDQQIPLLISGGIGHSTTFLYSAIAQHPHYNTIRTTGRAEATIL
                     ADIAHQFWHIPHEKIWIEDQSTNCGENARFSIALLNQAVERVHTAIVVQDPTMQRRTM
                     ATFRRMTGDNPDAPRWLSYPGFVPQLGNNADSVIFINQLQGLWPVERYLSLLTGELPR
                     LRDDSDGYGPRGRDFIVHVDFPAEVIHAWQTLKHDAVLIEAMESRSLR"
     gene            18817..20256
                     /gene="aldA"
                     /locus_tag="RN951_002605"
     CDS             18817..20256
                     /gene="aldA"
                     /locus_tag="RN951_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HDX2527587.1"
                     /translation="MSVPVQHPMYIDGQFVTWRGDAWIDVVNPATEAVISRIPDGQAE
                     DARKAIDAAERAQPEWEALPAIERASWLRKISAGIRERASEISALIVEEGGKIQQLAE
                     VEVAFTADYIDYMAEWARRYEGEIIQSDRPGENILLFKRALGVTTGILPWNFPFFLIA
                     RKMAPALLTGNTIVIKPSEFTPNNAIAFAKIVDEIGLPRGVFNLVLGRGETVGQELAG
                     NPKVAMVSMTGSVSAGEKIMATAAKNITKVCLELGGKAPAIVMDDADLELAVKAIVDS
                     RVINSGQVCNCAERVYVQKGIYDQFVNRLGEAMQAVQFGNPAERNDIAMGPLINAAAL
                     ERVEQKVARAVEEGARVAFGGKAVEGKGYYYPPTLLLDVRQEMSIMHEETFGPVLPVV
                     AFDTLEDAISMANDSDYGLTSSIYTQNLNVAMKAIKGLKFGETYINRENFEAMQGFHA
                     GWRKSGIGGADGKHGLHEYLQTQVVYLQS"
     gene            complement(20298..21298)
                     /gene="gap"
                     /locus_tag="RN951_002606"
                     /pseudo
     CDS             complement(20298..21298)
                     /gene="gap"
                     /locus_tag="RN951_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310049.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
     gene            21487..22017
                     /gene="cybB"
                     /locus_tag="RN951_002607"
     CDS             21487..22017
                     /gene="cybB"
                     /locus_tag="RN951_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415935.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b561"
                     /protein_id="HDX2527588.1"
                     /translation="MENKYSRLQISIHWLVFLLVIAAYCAMEFRGFFPRSDRPLINMI
                     HVSCGISILVLMVVRLLLRLKYPTPPIIPKPKPMMTGLAHLGHLVIYLLFIALPVIGL
                     VMMYNRGNPWFAFGLTMPYASEANFERVDSLKSWHETLANLGYFVIGLHAAAALAHHY
                     FWKDNTLLRMMPRKRS"
     gene            22262..22435
                     /locus_tag="RN951_002608"
     CDS             22262..22435
                     /locus_tag="RN951_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527589.1"
                     /translation="MKKLALILFMGTLVSFYADAGRKPCSGSKGGISHCTAGGKFVCN
                     DGSISASKKTCTN"
     gene            complement(22507..22656)
                     /gene="hokB"
                     /locus_tag="RN951_002609"
     CDS             complement(22507..22656)
                     /gene="hokB"
                     /locus_tag="RN951_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokB"
                     /protein_id="HDX2527590.1"
                     /translation="MKHNPLVVCLLIICITILTFTLLTRQTLYELRFRDGDKEVAALM
                     ACTSR"
     gene            23055..24695
                     /gene="trg"
                     /locus_tag="RN951_002610"
     CDS             23055..24695
                     /gene="trg"
                     /locus_tag="RN951_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein Trg"
                     /protein_id="HDX2527591.1"
                     /translation="MNTTPSQRLGFLHHIRLVPLFACILGGILVLFALSSALAGYFLW
                     QADRDQRDVTAEIEIRTGLANSSDFLRSARINMIQAGAASRIAEMEAMKRNIAQAESE
                     IKQSQQGYRAYQNRPVKTPADEALDTELNQRFQAYITGMQPMLKYAKNGMFEAIINHE
                     SEQIRPLDNAYTDILNKAVKIRSTRANQLAELAHQRTRLGGMFMIGAFVLALVMTLIT
                     FMVLRRIVIRPLQHAAQRIEKIASGDLTMNDEPAGRNEIGRLSRHLQQMQHSLGMTVG
                     TVRQGAEEIYRGTSEISAGNADLSSRTEEQAAAIEQTAASMEQLTATVKQNADNAHHA
                     SKLAQEVSIKASDGGQTVSGVVKTMGAISTSSKKISEITAVINSIAFQTNILALNAAV
                     EAARAGEQGRGFAVVASEVRTLASRSAQAAKEIEGLISESVRLIDLGSDEVATAGKTM
                     STIVDAVASVTHIMQEIAAASDEQSRGITQVSQAISEMDKVTQQNASLVEEASAAAVS
                     LEEQAARLTEAVDVFRLHKHSVSAEPRGAGEPVSFATV"
     gene            complement(24733..25656)
                     /locus_tag="RN951_002611"
     CDS             complement(24733..25656)
                     /locus_tag="RN951_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415939.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX2527592.1"
                     /translation="MEKNSLFSQRIRLRHLHTFVAVAQQGTLGRAAETLNLSQPALSK
                     TLNELEQLTGARLFERGRQGAQLTLPGEQFLTHAVRVLDAINTAGRSLHRKEGLNNDV
                     VRVGALPTAALGILPSVIGQFHQQQKETTLQVATMSNPMILAGLKTGEIDIGIGRMSD
                     PELMTGLNYELLFLESLKLVVRPNHPLLQENVTLSRVLEWPVVVSPEGTAPRQHSDAL
                     VQSQGCKIPSGCIETLSASLSRQLTVEYDYVWFVPSGAVKDDLRHATLVALPVPGHGA
                     GEPIGILTRVDATFSSGCQLMINAIRKSMPF"
     gene            25873..27216
                     /locus_tag="RN951_002612"
     CDS             25873..27216
                     /locus_tag="RN951_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDX2527593.1"
                     /translation="MANSITADEIREQFSQAMSAMYQQEVPQYGTLLELVADVNLAVL
                     ENNPQLHEKMVNADELARLNVERHGAIRVGTAQELATLRRMFAIMGMYPVSYYDLSQA
                     GVPVHSTAFRPIDDASLARNPFRVFTSLLRLELIENEILRQKAAEILRQRDIFTPRCR
                     QLLEEYEQQGGFNETQAQEFVQEALETFRWHQSATVDEETYRALHNEHRLIADVVCFP
                     GCHINHLTPRTLDIDRVQSMMPECGIEPKILIEGPPRREVPILLRQTSFKALEETVLF
                     AGQKQGTHTARFGEIEQRGVALTPKGRQLYDDLLRNAGTGQDNLTHQMHLQETFRTFP
                     DSEFLMRQQGLAWFRYRLTPSGEAHRQAIHPGDDPQPLIERGWVVAQPITYEDFLPVS
                     AAGIFQSNLGNETQTRSHGNASREAFEQALGCPVLDEFQLYQEAEERSKRRCGLL"
     gene            27441..29096
                     /gene="opgD"
                     /locus_tag="RN951_002613"
                     /gene_synonym="mdoD"
     CDS             27441..29096
                     /gene="opgD"
                     /locus_tag="RN951_002613"
                     /gene_synonym="mdoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415941.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucan biosynthesis protein OpgD"
                     /protein_id="HDX2527594.1"
                     /translation="MDRRRFIKGSMAMAAVCGTSGIASLFSQAAFAADSDIADGQTQR
                     FDFSILQSMAHDLAQTAWRGAPRPLPDTLATMTPQAYNSIQYDAEKSLWHNVENRQLD
                     AQFFHMGMGFRRRVRMFSVDPATHLAREIHFRPELFKYNDAGVDTKQLEGQSDLGFAG
                     FRVFKAPELARRDVVSFLGASYFRAVDDTYQYGLSARGLAIDTYTDSKEEFPDFTAFW
                     FDTVKPGATTFTVYALLDSASITGAYKFTIHCEKSQVIMDVENHLYARKDIKQLGIAP
                     MTSMFSCGTNERRMCDTIHPQIHDSDRLSMWRGNGEWICRPLNNPQKLQFNAYTDNNP
                     KGFGLLQLDRDFSHYQDIMGWYNKRPSLWVEPRNKWGKGTIGLMEIPTTGETLDNIVC
                     FWQPEKAVKAGDEFAFQYRLYWSAQPPVHCPLARVMATRTGMGGFSEGWAPGEHYPEK
                     WARRFAVDFVGGDLKAAAPKGIEPVITLSSGEAKQIEILYIEPIDGYRIQFDWYPTSD
                     STDPVDMRMYLRCQGDAISETWLYQYFPPAPDKRQYVDDRVMS"
     gene            29236..29460
                     /locus_tag="RN951_002614"
     CDS             29236..29460
                     /locus_tag="RN951_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415943.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcH family protein"
                     /protein_id="HDX2527595.1"
                     /translation="MFPEYRDLISRLKNENPRFMSLFDKHNKLDHEIARKEGSDGRGY
                     NAEVVRMKKQKLQLKDEMLKILQQESVKEV"
     gene            29523..30062
                     /gene="rimL"
                     /locus_tag="RN951_002615"
     CDS             29523..30062
                     /gene="rimL"
                     /locus_tag="RN951_002615"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12-serine
                     acetyltransferase"
                     /protein_id="HDX2527596.1"
                     /translation="MTETIKVSESLELHAVAENHVKPLYQLICKNKTWLQQSLNWPQF
                     VQSEEDTRKTVQGNVMLHQRGYAKMFMIFKEDELIGVISFNRIEPLNKTAEIGYWLDE
                     SHQGQGIISQALQALIHHYAQSGELRRFVIKCRVDNPQSNQVALRNGFILEGCLKQAE
                     FLNDAYDDVNLYARIIDSQ"
     gene            complement(30054..31034)
                     /locus_tag="RN951_002616"
     CDS             complement(30054..31034)
                     /locus_tag="RN951_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527597.1"
                     /translation="MRKYRLSEEQRAFSYQEDGTKKNVLLRQIIAISDFNDVIAGTAG
                     GWIDRETVLAQEGNCWIYDQNAIAFGGAVISGNTRITGTSVLWGEVYATDNVWIDNSE
                     ISQGAYISDSVTIHDSLVYGQCRIFGHALIDQHSMIVAAQGLTPDHQLLLQIYDRARV
                     SASRIVHQAQIYGDAVVRYAFIEHRAEVFDFASIEGNEENNVWLCDCAKVYGHAQVKA
                     GIEEDAIPTIHYSSQVAEYAIVEGNCVLKHHVLVGGNAVVRGGPILLDEHVVIQGESR
                     ITGAVIIENHVELTDHAVVEAFDGDTVHVRGPKVINGEERITRTPLAGLL"
BASE COUNT         7980 a         7084 c         8129 g         7914 t
ORIGIN      
        1 ttgacggcga ccaggccatc gtcaataacg aaggcgagag cactatcacc aatggcggca
       61 ccggcactca gatcaacggt aacgacgcca ccgcgaataa cagtggaaaa accactgttg
      121 atggaaaaga ttccacgggt accaaaatcg cgggcaatat cggcattgta aatctggatg
      181 gtagcctgac tgttacaggc ggtgcgcatg gtgttgagaa cattggtgac aacggcacgg
      241 ttaacaacaa aggagatatt gttgtttccg atactggatc gattggcgtg ctcatcaacg
      301 gtgagggggc aacagtatcc aatacgggtg atgttaacgt tagcaatgaa gcgacagggt
      361 tcagcatcac aaccaacagt gggaaggttt cgctggcagg cagtatgcag gttggcgatt
      421 tctcgaccgg ggtagatctt aatggcaaca ataacagcgt gacgctggcg gcaaaagatc
      481 taaaagtggt cgggcagaaa gcgacgggca taaacgtttc tggcgatgcg aatacagtga
      541 atatcactgg taacgttctg gttgataagg ataaaaccgc agacaatgcg gcggaatatt
      601 tcttcgatcc atccgtgggt atcaacgttt acggcagtga taataacgtg acgctggatg
      661 gaaagttaac tgttgtatca gacagtgagg ttacttctcg tcagagtaat ttatttgatg
      721 gcagcgcaga gaaaacgtca ggtctggttg tgattggcga tggcaatacc gttaatatga
      781 atggtggact tgaactgatt ggagagaaaa acgcgcttgc agatgggtcg caggttactt
      841 ccttgcgcac aggatatagt tataccagcg ttattgtcgt tagtggtgag tcgtcggtat
      901 atctgaatgg agatacgaca atcagcggag aattccctct ggggtttgcc ggggttattc
      961 gggtacagga taaagctttg ctggaaattg gcagtggcgc tacgctaaca atgcaggata
     1021 ttgacagttt tgaacatcat gggacaagaa ccccagaact tacttatgct gattccggtg
     1081 cgaaaattgt taataaaggt actgttgaaa ttcagaattt aggttttgct tttgttactg
     1141 gtgaaaatac aacaggtata aatagtggca cgatctcgtt attacaaaat ggtaaagatc
     1201 cggcaccgtc tcccattgtt ttactggcta ctaacggagg gagcgccact aatgcaggta
     1261 cgatcacagg taaagtgacg gaacaacata gcgtatttaa caagtattca acgggcacat
     1321 cgaattcatt tatttttaat aacgatgtca gtagcataac agggttagtc gctcaatcga
     1381 atagcacaat tatcaatact gacagcggca tcattgattt gtatggtcgt ggtagtgtcg
     1441 gcatgcttgc tatagcagat tcaacagcag aaaatcaggg taaaattaca ctggattcta
     1501 tgtgggtaga tgcaaatgac actaccgcaa tgcgagatat agctagcaac agcgccattg
     1561 acttcggtac aggtgtggga gttggtactg atagttatag tggtgcaggg aaaaatgcaa
     1621 cagcaattaa ccaattgggc ggtgttataa ctatttataa cgccggcgca ggtatggcgg
     1681 cctatggcgc cagcaataca gttattaacc aggggacgat taacctcgaa aaaaatgata
     1741 attatgacga tagtctggca gcaaatactc tggtagggat ggctgtttat gagcatggta
     1801 ctgctatcaa cgaccagacg ggtgttatca atatcaatgt tggtactggt caggcgtttt
     1861 ataacgatgg cacaggaaca attgttaact atggtacaat ctgcactttc ggcgtgtgcc
     1921 aatcggggaa tgagtacaat aatacagatg atttcacctc actgatctat accggtggcg
     1981 atacgattac acgaagcgga gaaactgtaa cgctaaataa atctgctgct gtgactgata
     2041 agctggctgg gaatgttgtt aatagcggaa cgctttccgg tgatcaaatt acggtatcaa
     2101 gcggtcttct ggaaaatacc agcggtggca tcatcaataa cttagtaaaa cttgacaagg
     2161 gtgccgtcat taaaaatgcc ggggtgatga cgaataacgt cgatgttagc ggtggaatcc
     2221 tcaataatgc cggagaaatg actgcgcaaa ttaccatgaa tgctggtgct gatagttcgt
     2281 tagtgaacaa caccggaacc atcaataaaa tcgtgcagaa cgcgggggta ttcaataata
     2341 gtggcagtgt aacagggcgg atgatgtcgg ctggcggggt ctttaataat caaactgacg
     2401 gggcgattat gagaggtgct gcgctgacag gtactgcagt ggcaaataac gaaggaacct
     2461 ggaacctcgg aagtagtagt gagggtaaca acaccgggat gctggaagtt aataataatt
     2521 cagctttcaa taaccgcggc gagtttattc ttgataacga caagaatgct gtgcacatca
     2581 accagtccgg tacgctttat aataccggtc acatgaacat cagtaattct tcccacaacg
     2641 gagccgttaa tatgtggggc ggaaatggtc gttttatcaa tgacggaacg attgatgttt
     2701 ctgcgaagtc actggtagtc agcgctaata atgccggcga tcagaatgcc ttcttctgga
     2761 accaggataa cggggtcatc aacttcgatc acgacagcgc cagtgccgtg aaagtcaccc
     2821 acagcaactt tattgcccag aatgacggca tcatgaacat cagcggcacc ggtgctgtgg
     2881 ctatggaagg tgataagaac gcgcagctgg ttaacaatgg caccatcaac ctcggtaccg
     2941 caggcactac tgacacgggt atgatcggta tgcaactcga tgccaacgcc acggcggatg
     3001 cggtaatcga aaacaacggc accatcaata tcttcgccaa tgactcgttt gcatttagcg
     3061 tactgggtac agtaggtcat gtggttaaca acggcacggt ggtgattgcc gatggggtta
     3121 cgggttctgg actgatcaag cagggcgaca gcatcaatgt tgaaggtatg aacggtaaca
     3181 acggtaatag cagcgaagtg cattatggcg actatacgtt gccggatgtg ccgaagccca
     3241 atacggttag tgtaacgtcg ggaagtgatg aggctggtgg cagcatgaac aacctcaacg
     3301 gctatgtcgt cggtaccaac gttaacggca gcgccgggaa gctgaaggtt aacaatgcca
     3361 gcatgaacgg cgtggagatt aacacgggct ttaccgctgg tacggcagac accactgtga
     3421 gttttgataa cgtagtggaa ggtagcaacc tgaccgacgc tgacgccatc acctcaacgt
     3481 ccgtggtatg gactgccaaa ggcagcaccg atgccagcgg taacgttgac gtcaccatga
     3541 gcaaaaatgc ctacaccgat gtggcaacag atgcctcggt gaatgacatc gcgaaagcac
     3601 tggatgcggg ttacaccaac aacgaactgt ttaccagcct gaacgtcggc acgactgctg
     3661 aactgaacag tgctctgaaa caggtcagcg gtagccaggc gaccacggta ttccgcgaag
     3721 cgcgcgtgtt aagcaaccgc tttagtatgc tggcagatgc cgcgccgaaa gtgggtaacg
     3781 gtctggcgtt caacgttgtc gcgaaaggcg atccgcgtgc cgagttaggt aataataccg
     3841 aatacgacat gctggcattg cgtaaaacta tcgacctgag cgaaagccag acgatgagtc
     3901 tggagtacgg tatcgctcgt ctcgatggtg atggtgcgca gaaagcgggt gataatggcg
     3961 ttacaggcgg ttatagccag ttttttggcc tgaaacatca gatgtcgttc gataacggca
     4021 tgaactggaa taacgccttg cgttacgacg ttcacaacct tgacagcagc cgctcgattg
     4081 catttggcaa cacgaacaaa acggctgata ccgacgtgaa acagcagtac ctggagttcc
     4141 gcagcgaagg ggcgaagact ttcgaaccga gcgaaggact gaaggttacg ccatatgcgg
     4201 gtgtaaaact gcgtcacaca ctggaaggtg gctatcagga gcgcaatgcc ggagacttta
     4261 acctgaatat gaacagtggc agcgaaacgg cggtggacag catcgtcggg ctgaaactgg
     4321 actacgcagg taaagacggc tggagcgcta gcgctacgct ggaaggcggg ccgaacctga
     4381 gctacgcgaa gagccagcgt acggcaagcc tggcaggcgc aggcagtcag cactttaacg
     4441 tcgatgacgg tcagaagggc ggcggcatca atagcctgac aagcgtcggc gtgaagtaca
     4501 gcagcaaaga aagttcgctg aatctggatg cgtacaactg gaaagaggat ggcatcagcg
     4561 ataaaggcgt gatgctgaac ttcaagaaaa cgttctaatt tttagcatgt gatccctaaa
     4621 ccgcaacgct gatacaggtt gcggtttttt tattgccgga tgtggtacgt gacgcgtttt
     4681 gttttgtgtc tttcaggaca atagagcaac tcatccagta atcttgttta caccttcgca
     4741 ttatttatct cttttcgttt ctatactgat ttttcttaat ccgttttatt acagggcagg
     4801 gtgcgatgag cagcaataca tttactctcg gtacaaaatc cgttaaccgt cttggttatg
     4861 gcgcgatgca actggcaggt cctggagttt ttggcccccc acgagatcgc cacgtcgcta
     4921 taaccgtgct gcgtgaggcg ctggcattgg gcgtcaatca tattgatacc agcgactttt
     4981 atggtccgca cgtcaccaat cagattatcc gcgaagcgct ttatccttac tctgacgacc
     5041 tgacaattgt cactaaaatt ggtgcgcggc gtggagagga cgcatcctgg ttgcccgcat
     5101 tttctccggc agagctgcaa aaagcggtgc acgataatct acgtaatctc gggctggacg
     5161 tgctggatgt ggttaacctg cgcgttatga tgggggatgg tcatggccca gcggaaggat
     5221 cgattgaggc cagcctgacc gtgctggcag agatgcaaca acaaggcctg gtaaaacata
     5281 ttggcctgag caacgtcaca ccgacgcagg ttgcagaggc gcgcaagatt gccgaaattg
     5341 tctgtgtgca aaacgaatac aacatcgcgc accgtgctga tgatgcaatg attgatgctt
     5401 tggcccacga tggcattgcc tacgtgccgt tcttcccgct cgggggcttt acaccgctgc
     5461 aatcgtccac actttccgat gttgctgcga gcctgggtgc aacaccaatg caggtggcgc
     5521 tggcgtggct gttacagcgt tcaccgaata ttttgctgat cccagggacg tcttcggttg
     5581 cgcatttacg ggagaatatg gctgctgaaa aattgcatct ttctgaggaa gtgttgtcta
     5641 cgttggatgg tatttcgcga gaataacgaa tatacaaaag ggaaagatgc atttcccttt
     5701 ttttcttttt taatggcatg gggtgcatat gtttaaggcc aggaattgcg gctggatacg
     5761 tttactgccc ctgtttatgc tgagtctacc agtacaggcg gaacttcgat gtgttgcaaa
     5821 tgcagttgat attgaatcat ttttttctgc ggctaccgct gaagataaac aacaagttga
     5881 acaagctatc aacagtagcg tgaatcttgt ccccttcggt ttatctgcat cgaactggaa
     5941 agtgcatcgt ggcgatttag tggtagaagg taatatagag agtaatcaaa aattgattgt
     6001 tcttgggaat ttgacagtca aaggtaatat ttccactttc tctctttcta atccatgggt
     6061 tattctcggt aacgtgacgg caacgaatat agttgcggat tcaccactgt taattaccgg
     6121 ttcgataaat gcaagtggac tggtatttat cgactcatat tacgataatc cgtctacgat
     6181 taaggggagt attaatgcgc gtgggatatt tatcaatgac ataattgcac ctgttgttgc
     6241 gtcttcgaca aatagtgaat tcatggtccg tgcgagtgac aaacatgaca ctgaaaatgt
     6301 caaaaaagcg ctgatgataa taaatcctga tgcatattat tgggggctaa ttaatgatga
     6361 agatgctctg aaagaaattt ttaagcgaag caatattcgc atggcaggga atgtctgtaa
     6421 tcagatgaaa aaagaagcgc tgtttcgccc taagccttct cctgagttag tgcaagaatt
     6481 gcaaatgctg gatgaaggca aagttgctgc atttgaagga cgagacattg cgacatttga
     6541 tcttgccgta atgcgaactc tcccaaggct taaaggaatt tcagctaacc tacgcaaaca
     6601 acttattaat agcaatgatg aacaaacgat tgaaagtatg gcgagatata tgcctgacaa
     6661 tgagattctg gagttgaccg atcagcaatt gggttaccag cctgttgttc tggggttgct
     6721 cgaccgtgaa ccgctctctg tcgaaataat gacgcgaatg agtcgtctac ctgatggtgt
     6781 cggtccgttg aatcttgcgc tacgtgaaaa tctccctctg gatatcgtca tgactctggc
     6841 gaaaagagat tgggatatga tcattcagga gctttataaa gatgcgtggt tattgcctga
     6901 atccattatt gatggctata tccgcagtga tgattcctct attcgtcagg tcggtgctgg
     6961 aggacaactc acctacaatc aggcaatgca gttggcgaac gattcatcaa acaatgttgt
     7021 cacaagctta gcgttcaagc tggcagagat gaaacaccat ggtcaattgt tgcggatgac
     7081 gccacaagag agtgacaaag ttgcaggcta tttataccaa aaattcgaga atgacgatga
     7141 tctaatacgt gtgttatttt tagcattgcc agataactta cagtttaatt ttgttaaaag
     7201 gatggagaaa aaatccccgg cctacttttg ctgtcgggat atgcaggtaa ttcactctga
     7261 cgctgcttta caacggttat tgacacgttt caacgatcct gaagggtgga gtaatctggc
     7321 gaaaaatcag tatctgagca cgtcgatgaa acaaaaaatt tggcaacgtg ctttatcgca
     7381 tcggaaaaat aatccgaaag cagattcaga tgcatatgaa accagcgctg atatgatttt
     7441 gtctgagctg attagccacg gcgaagttga tgaccagatg ctattaaatg ccaccgccct
     7501 gatacgttcg gacgactggg actttttaga gagtgcatta attagttggg ataatttacc
     7561 cgctgttgtt ctcaaggaat tacagcaaaa cacgccacgc aatgatattt gggcgaagtt
     7621 ttttctgagg caggaaaaca gttcccgtgc gcaggttgac gaagcgttac gtgtttatta
     7681 tgcactagac cccgatgcgt tagcacaact ggatgtactg gcaaaacaac cggatcgtat
     7741 atggtggagt acactggcga aaagcaatct cacatttttc aagttcggcg cacttaacaa
     7801 ccgccacaca ccgcctgcag tactggcggc agaaattgat cccgagtggt ggattgtggc
     7861 gatgaataat ccccgttttc cagttgatgt attaaaggcg aggctgaaac gtgatccttt
     7921 gctggcgtta gagcttgtta accctgaact ggatttagtc cgccagctgg cgcttaacgg
     7981 taagacgcgc gcaatacggg aacaagcgat gagaaaactt gatgagttgt attgatccac
     8041 aacgtaatgt tttttaacta tctgattaat tggggataat cattcctgac agtgagtccc
     8101 caataccttg atatattctg aatttttaat gaaacggcgt gttgcgatat ctccgtcagg
     8161 ggaattgatg caccatagcg caaaccgaat tatcaaggat tgataatgac gctctaccag
     8221 ataaaaccgc tctttcagtc gctgttaagg ccgacgatgt tttggcttta taagcaccac
     8281 gttacagcga atcacatcac tcttgctgca ctggcgcttt ctcttcttac cggattgctg
     8341 ttgatgttgg cggcacaacc catcctcttt ttgctattgc ccatcgtgct ttttatccgt
     8401 atggcgctca atgcgctgga tggcatgttg gcgcgtgagt gcaaccagca aacacgtctg
     8461 ggggcgattt tgaatgagac tggcgatgtt atttccgata ttgcgctcta tttaccattt
     8521 ttatttttac cggaaagtaa cgcatcactc gtgatactca tgttattttg caccatattg
     8581 accgagtttt gcggtttact cgcgcagacg attaacggtg ttcgcagtta tgccggtcca
     8641 tttggcaaaa gcgatcgcgc gttaatattt ggtctgtggg gtctggccgt tgccatttat
     8701 ccacagtgga tgcagtggaa taatctttta tggagcattg cttcaattct gcttctctgg
     8761 actgcgatta atcgttgtcg gagtgtgctt cttatgagcg ctgaaatata atgctggaaa
     8821 aatctctggc aacacttttc gcgttgttaa ttttagcaac gctgataaac cgttttctgc
     8881 tatggcggtt accggagaga aaagggggtg aggttacatt acgtattcgt acctggtggg
     8941 gcatcgtcat ttgtttttca atggtgattt caggtccacg ctggatgacg ttgacgtttt
     9001 ttgcgctgat aagttttctg gcattgaaag aatattgtac gcttatatct gtacattttc
     9061 cgcgttggtt atattggggt attcctctta actatttgct tatcggtttt aattgctttg
     9121 agctgtttct gttatttata cctttggctg ggtttctgat attagccacc gggcaagttt
     9181 tagtgggtga cccctctggt tttctgcata ccgtgagcgc cattttttgg ggctggataa
     9241 tgaccgtttt cgccttgagt catgccgcct ggttattaat gttgccaacc acaaatatcc
     9301 agggcggggc gttactggtg ttatttcttt tggcattaac cgagtcaaac gatattgcac
     9361 agtatttatg gggaaaatcc tgcggcagaa gaaaagtggt ccctaaagtc agcccgggaa
     9421 aaacattgga aggtctgatg ggcggcgtca tcaccatcat gattgcgtca ctgattatcg
     9481 gaccgttact gacaccgcta aatacattac aggcattatt agcgggtttg ttaattggta
     9541 ttagtggttt ttgcggcgat gtcgtgatgt cagccatcaa acgagatatt ggtgttaaag
     9601 atagcggaaa actattgcca ggacatggcg gactccttga caggattgac tcattaattt
     9661 tcaccgctcc ggtatttttt tattttatac gctactgctg ttactgaagg aaaatagaga
     9721 aaatggaaaa ttcacgcatc cctggggaac atttttttac caccagtgat aatacagcgt
     9781 tgttttatcg gcactggccc gctttacagc ccggggcgaa aaaggtcatc gtcttatttc
     9841 atcgcgggca tgaacattct ggtcgtctac aacatctcgt tgatgaactg gcgatgccag
     9901 atactgcttt ttatgcctgg gatgcccgag ggcatggaaa aagttcgggg ccgcgtggtt
     9961 atagcccatc tcttgcgcgt tcagtgcggg atgtcgatga atttgtccgt tttgctgcca
    10021 gcgacagcca ggttggactg gaagaggtgg tagtgatcgc gcaaagcgtc ggcgcagtgc
    10081 tggttgccac atggattcat gattatgcac ctgcaattcg cgggctggtg ctggcttctc
    10141 cggcctttaa ggttaaattg tatgtgccgc tggcacgtcc tgcgctggcg ttatggcatc
    10201 gtctgcgtgg tctgtttttt attaattcct atgtgaaagg acgctatttg acccacgatc
    10261 ggcaacgggg ggcgagtttc aataatgatc cgctgatcac acgggcgatt gccgttaata
    10321 tcttgctcga tctctacaaa acgtctgaac gtattattag agatgcggcg gcgattacgc
    10381 tccccacgca acttctgata tcaggcgatg actatgtggt gcatcgccaa ccgcagattg
    10441 atttttatca gagattacgt agccctctga aagagctgca tctgctgcca ggcttttatc
    10501 acgacacgtt gggtgaagag aacagggcgc tggcatttga aaaaatgcaa agctttatta
    10561 gtcgtttata tgctaacaaa tcgcaaaaat ttgattatca gcatgaagac tgcacaggac
    10621 catcagcgga tcgatggcgg ctactttctg gtggacccgt gccattatcg ccggttgatt
    10681 tagcgtatcg ctttatgcga aaggcgatga aattgttcgg gacgcactct tcgggcctgc
    10741 atctcggaat gagcaccggc tttgattcag gcagttcgct ggattatgtc tatcaaaatc
    10801 aaccgcaagg tagtaacgca ttcgggcgtt tagtcgacaa aatctacctg aacagtgttg
    10861 gctggcgcgg tattcgccag cgcaaaaccc atttacaaat actgattaaa caagccgttg
    10921 ccgatctcca cgccaaaggt ttagccgtcc gcgtggttga cattgccgca gggcatgggc
    10981 gctatgtact ggatgcgctg gcaaacgagc ctgccgtaag cgatattttg ttacgtgatt
    11041 acagcgagtt aaatgttgca caggggcaag agatgattgc tcaacgggga atgtctgggc
    11101 gggtgcgttt tgaacagggc gatgcgttta acccggagga actcagcgcg ttaactccgc
    11161 ggcctacgct ggcgattgtc tctggcctgt atgagctttt tcccgaaaat gagcaggtaa
    11221 aaaactcact cgcaggtctt gccaatgcca tcgaaccggg cggcattctc atctacaccg
    11281 ggcagccgtg gcaccctcaa ctggagatga ttgccggggt gttaaccagt cataaagatg
    11341 gtaaaccgtg ggtaatgcgc gtgcgttcgc aaggggagat ggattcactc gtgcgtgatg
    11401 ccggatttga taaatgcaca caacggattg atgagtgggg tatttttacg gtttcgatgg
    11461 cggtgcgtcg tgataactga acgtcggaac gtattgctac aaggcgctgg ctggttattg
    11521 ttgctggccc cgtttttctt cttcacctat ggatctctta atcagttcac cgcggttcag
    11581 gaccttaaca gccatgatat ccccagtcag gtattcggtt gggaaacggc gatccctttt
    11641 cttccctgga ctattgttcc ttactggagt ctggatcttt tatatggatt ttcgctgttc
    11701 gtttgtagca cgacattcga acagcgccga cttgtccacc ggcttattct ggcaacggta
    11761 atggcctgct gcggtttttt gctctatccg ctgaagttta gttttatccg tcctgaagtg
    11821 agtggggtga cgggatggct attttcgcaa cttgaactgt ttgatctgcc ttataaccag
    11881 tctccttcgc tgcatattat tctctgctgg ctactttggc gtcactttcg tcagcatctg
    11941 gctgagaggt ggcgtaaagt ctgcggcgga tggtttttac tcatcgccat ttcgacgctg
    12001 acgacctggc agcatcattt tattgatgtc atcacagggc tggcggtagg tatgttgatt
    12061 gactggatgg tgcccgtcga ccgtcgttgg aattatcaga aacctgatca acgtcgaatc
    12121 aaaatagcac tgccctatgt cgtaggcgcg ggctcgtgca ttgtattgat ggagctaatg
    12181 atgatgattc agttatggtg gtcagtctgg ttatgttggc cagtattatc gctactcata
    12241 attggccgtg ggtacggtgg gcttggcgcg ataacaacag ggaaagatag tcaggggaaa
    12301 ctaccgcccg ccgtttactg gctgacattg ccctgccgca tcgggatgtg gctgtctatg
    12361 cgttggtttt gtcgtcgcct ggagccggtg agcaaaatga ctgctggtgt ttatttaggg
    12421 gcgtttccac gacatattcc ggcacagaat gcggttctgg acgtcacctt tgaattccct
    12481 cgcggacgag ccacaaaaga tcgactctat ttttgtgtac cgatgctgga tctggtggtt
    12541 ccggaagagg gggagctccg acaggccgtg gcgatgctgg aaacattacg cgaagagcaa
    12601 ggcagcgttc tggtccattg tgcattggga ttatcgcgca gtgcgctggt ggtggcggca
    12661 tggttgttat gttacggaca ctgtaaaacc gttaatgaag cgattagcta tattcgagcc
    12721 agacgcccgc agattgtgct gacagacgag cacaaagcga tgctgagatt atgggaaaac
    12781 aggtaagtgg attgagatgt ggactgaata tctacagtcc acatcaagac cgtgtccggt
    12841 tatgcagaaa caatgctgtc gatggctgct tttgcgtcag actgtgcttt cgctgccatt
    12901 tccggaccgt atgcgatccc ttcggcgaag acaaatttca catcggtaat gccgataaag
    12961 ccgaggaacg tggacagata cggcgtcacc aggtccgttg gtccatcttt gtggatcccg
    13021 ccgcggctgg taataacgat ggctttttta cccgttacca gaccttccgg accgttctcg
    13081 gtatagcgga aagtaacgcc tgcgcgggca accaggtcaa aatagttttt caactgagtc
    13141 gagatgttga agttatacat cggtgccgca ataacgataa cgtcgtgggc tttcagctcg
    13201 gcaatcaact catcggaaag tgccagagct tcctgctgac gcggagtcag cggcgcatcg
    13261 ctcggacgca gagcgccaac cagttcgcca tccagtaccg gaatcggatt tgcagccagg
    13321 tcgcgaacgg tgatttcatc agcggagtgc ttttcgcgcc attgttcaac aaaataatcg
    13381 gacaactgat tagactgaga gtaccctgcc aggatgctgg atttaagaac taataccttg
    13441 ctcatggtgt ttccttatag atgtttgaat gggcgatgcc ccgttgcttg ttgacacttt
    13501 attcacaatc ctgccacaga gatagcgcaa taaatcgaag cctatgttcg aatttattga
    13561 acaacgcata gaaagccgcg atgtggtact ctatatctat catttaaaag aaaattaatc
    13621 aggcagacta ctgcccacta acgttatgac agaacaacaa aaattgacct ttacggcctt
    13681 gcagcagcgg ctggattcgc tgatgctgcg tgacagactg cgtttttctc gccgtctgca
    13741 cggcgtgaag aaggttaaaa atcctgatgc acaacaggcc attttccagg agatggcgaa
    13801 agagattgac caggcggcag ggaaagtcct gctgcgtgaa gcggcacgac cggaaattac
    13861 ttatcctgac aatttaccgg ttagtcagaa aaaacaggac attctcgaag cgattcgtga
    13921 tcaccaggtg gtgatcgtcg ccggggaaac gggttctggt aaaacgactc agttaccgaa
    13981 aatctgtatg gagctggggc gcgggattaa aggactgatc ggccataccc agccgcgtcg
    14041 tctggcggca agaacagtgg cgaaccgtat tgcggaagag ctgaaaacgg agccgggcgg
    14101 ttgcatcggt tacaaagtgc gtttcagcga tcacgtaagt gataacacga tggtcaagct
    14161 gatgaccgac ggtatcctgc tggcggagat ccagcaagac cgcctgctga tgcagtacga
    14221 cactatcatt attgacgaag cgcacgaacg cagcctgaat atcgattttt tgctcggcta
    14281 tttgaaagag ttgctgccgc ggcgtcctga cctaaaaatc attatcactt ccgcgactat
    14341 cgacccggaa cgcttttcgc gccactttaa taatgcgccg attattgaag tctccggtcg
    14401 gacctatccg gtggaagtgc gctatcgccc gattgttgaa gaagccgatg acaccgagcg
    14461 cgatcagttg caggcgattt ttgacgccgt agacgaactg agtcaggaaa gccatggcga
    14521 cattctgatc tttatgagcg gcgagcggga aatccgcgat accgccgatg cgctgaacaa
    14581 gctgaactta cgccataccg aaatcttgcc gctttatgcg cggctttcga acagcgaaca
    14641 aaatagggta ttccagtcgc acagcggacg gcgcattgtg ctggcgacca acgtcgcgga
    14701 aacgtcgctg accgtaccgg ggattaaata cgttatcgac cccggtacag cgcgtatcag
    14761 ccgctacagc tatcgcacca aagtgcagcg tttgccgatt gagccgattt cccaggcgtc
    14821 tgccaatcag cgtaaaggcc gctgtggtcg tgtgtccgaa gggatctgta ttcgtctcta
    14881 ttccgaagac gatttcctct cgcgcccgga gtttaccgat ccggagattc tgcgtaccaa
    14941 cctggcctcg gttattttgc agatgaccgc gctggggctg ggcgatatcg ctgcgttccc
    15001 gtttgtcgaa gcaccggata aacgcaatat ccaggatggc gtgcgtctgc tcgaagagct
    15061 gggcgcgatc accactgatg aacaggccag cgcctataaa ctgacgccgc tcggtcgcca
    15121 gctctcgcag ttgcctgtcg acccacgtct ggcgcgtatg gtgctggaag cgcaaaaaca
    15181 tggctgcgtg cgtgaggcga tgattatcac gtccgcgctc tccattcagg atccgcgcga
    15241 acgtccgatg gacaaacagc aggcatcgga cgaaaaacat cgtcgcttcc acgacaaaga
    15301 gtctgacttt ctcgcgtttg tgaatctgtg gaattatctt ggcgagcagc aaaaggcgct
    15361 ttcttccaac gccttccgtc gcctgtgtcg taccgattat ctcaactatc tgcgcgtgcg
    15421 cgaatggcag gatatctaca cccagttgcg tcaggtggtg aaagaacttg gcattccggt
    15481 taacagcgaa ccggcggagt atcgcgaaat tcacattgcg ttgctgaccg gtttactttc
    15541 ccatatcggc atgaaagatg ccgataaaca agaatatacc ggcgcacgta acgcgcgttt
    15601 ctccatcttc cccggttctg gtttattcaa aaaaccgcct aaatgggtaa tggtggcgga
    15661 actggtagaa accagccgcc tgtgggggcg cattgctgcg cgtatcgacc cggaatgggt
    15721 ggagccagtt gctcagcatt tgattaaacg cacctacagc gaaccgcact gggaacgggc
    15781 gcagggcgcg gtgatggcaa cggaaaaagt cactgtttat ggtttgccga ttgttgccgc
    15841 gcgcaaggtc aactacagcc agatcgatcc ggcgttatgt cgtgaactct ttattcgcca
    15901 cgcgctggtg gaaggtgact ggcagacgcg tcacgcattc ttccgtgaaa acctgaaact
    15961 acgggcggaa gtagaagagc tggaacacaa atcacgtcgc cgcgatattc tggttgatga
    16021 cgaaacgttg tttgagttct acgaccagcg catcagccac gatgtaatct ccgctcgcca
    16081 cttcgacagc tggtggaaaa aagtcagccg cgaaacgcct gatttgctca actttgaaaa
    16141 aagcatgttg atcaaagagg gcgcagaaaa aatcagcaag ctggattacc cgaacttctg
    16201 gcatcagggc aatctcaagc tgcgtttgag ctatcagttt gagcccggcg cggatgctga
    16261 cggtgtgacc gtacatattc cgctgccgtt acttaaccag gttgaggaaa gcgggtttga
    16321 atggcagatc cccggtctgc gccgcgaact ggtgattgct ctgattaaat cgttgccgaa
    16381 accggtacgc cgtaattttg tacccgcgcc aaactatgcc gaagcgtttt taggccgcgt
    16441 caaaccgctg gagttaccgt tgctcgacag ccttgagcgc gagttacggc ggatgaccgg
    16501 cgttaccgtt gaccgcgaag actggcactg ggatcaggtg cccgatcacc tgaaaattac
    16561 cttccgcgtg gtggatgaca aaaacaagaa gctaaaagaa gggcgctcgc tacaagatct
    16621 gaaagatgcg ctgaaaggca aagtgcagga aacgctatct gcggtggcgg atgacggtat
    16681 cgagcagagc ggcttacata tctggagttt tggtcagctg ccggaaagct acgaacagaa
    16741 gcgtggcaac tacaaagtga aggcgtggcc ggcgctggtg gatgagcgcg acagtgtggc
    16801 gatcaaactg tttgataacc cgctggagca aaagcaggca atgtggaacg gtcttcgccg
    16861 tctactgctg ctgaatattc catcgccaat caaatattta catgaaaagt taccgaacaa
    16921 agccaagctg ggactgtact ttaacccgta tggcaaagtg ctggagctga tcgacgactg
    16981 tatctcctgc ggtgtggata aattgatcga cgccaatggt ggcccggtct ggacggaaga
    17041 aggctttgct gcgctgcatg aaaaagtgcg tgccgaactg aacgacacgg tggtggatat
    17101 tgcgaagcag gtcgagcaaa tccttacggc agtgttcaat atcaacaaac gtctgaaagg
    17161 gcgggtggat atgaccatgg cgctggggct ttctgacatt aaagcgcaga tgggcgggtt
    17221 ggtatatcgc ggttttgtca ctggtaacgg cttcaaacgg ctgggcgaca cgctgcgata
    17281 tttgcaggcg attgaaaaac ggctggaaaa actggcggtt gatccacatc gcgaccgtgc
    17341 gcagatgctg aaagtcgaaa acgtccagca ggcgtggcag caatggatca acaaactgcc
    17401 gcccgcacgt cgtgaggatg aagacgtgaa agagatccgt tggatgatag aagagttgcg
    17461 cgttagttac ttcgctcaac aacttggtac gccttatccg atttcagata agcgtatttt
    17521 gcaggcgatg gagcagatta gcggttaacc ctgctatttg cctgataaag aaaaaacccg
    17581 gtaagcattt agcgccgggt tttttattaa ttctaaaacg gtaagggtaa aaattcagga
    17641 attcagaaaa atacaattct ctgctgcaag atgaataatg tttatctaca gcatttcctt
    17701 aaaagatatg tcaggcttgc ggagtggcgg ttaaggacat acgatttcct cctttcagag
    17761 tgctccgctt ctcactatta tctcacgcag tattcttaag ggaacgataa ggaggaacca
    17821 tgaacattac cccgtttccg acgctttcgc cggcaactat agatgccata aatgttatcg
    17881 gacagtggct ggcgcaggat gatttctccg gtgaggtgcc gtatcaggcc gattgcgtga
    17941 tccttgcagg caatgcggtt atgccgacta tcgatgcggc atgtaagatt gcccgcgatc
    18001 agcaaattcc tttactgatt agtggtggta tcggtcactc gacaactttt ttgtatagcg
    18061 ccatcgcaca gcatccgcac tacaacacta tccgcaccac tggcagagca gaagcgacca
    18121 tcctggcgga tatcgctcat cagttctggc acattccgca tgaaaaaatc tggattgaag
    18181 accagtcaac aaactgcggt gaaaacgcac gctttagcat cgcgctattg aatcaggccg
    18241 tagaacgagt tcatacggct atcgttgttc aggaccccac catgcagcgg cgcacgatgg
    18301 cgacgttccg ccgtatgact ggggacaatc ccgatgcacc acgctggtta agttatcccg
    18361 gattcgttcc tcagttagga aataacgcag acagtgtaat ctttattaat cagttacaag
    18421 gattatggcc agttgagcgt tatctctcac tactcactgg cgagctgccg cgtttacgcg
    18481 atgatagcga tggctacggt ccccgcgggc gagattttat cgttcacgtt gattttccgg
    18541 cagaagtcat ccatgcatgg caaacgctga aacatgatgc ggtgctcatc gaggcgatgg
    18601 aaagtcgctc gttacgttaa aaattgcccg tttgtgaacc acttgtttgc aaacgggcat
    18661 gactcctgac ttttatttct gccttttatt ccttttacac ttgtttttat gaagcccttc
    18721 acagaattgt cctttcacga tgccgtctct ctgatgattg atgttaatta acaatgtatt
    18781 caccgaaaac aaacatataa atcacaggag tcgcccatgt cagtacccgt tcaacatcct
    18841 atgtatatcg atggacagtt tgttacctgg cgtggagacg catggattga tgtggtaaac
    18901 cctgctacag aggctgtcat ttcccgcata cccgatggtc aggccgagga tgcccgtaag
    18961 gcaatcgatg cagcagaacg tgcacaacca gaatgggaag cgttgcctgc tattgaacgc
    19021 gccagttggt tgcgcaaaat ctccgccggg atccgcgaac gcgccagtga aatcagtgcg
    19081 ctgattgttg aagaaggggg caagatccag cagctggctg aagtcgaagt ggcttttact
    19141 gccgactata tcgattacat ggcggagtgg gcacggcgtt acgagggcga gattattcaa
    19201 agcgatcgtc caggagaaaa tattcttttg tttaaacgtg cgcttggtgt gactaccggc
    19261 attctgccgt ggaacttccc gttcttcctc attgcccgca aaatggctcc cgctcttttg
    19321 accggtaata ccatcgtcat taaacctagt gaatttacgc caaacaatgc gattgcattc
    19381 gccaaaatcg tcgatgaaat aggccttccg cgcggcgtgt ttaaccttgt actggggcgt
    19441 ggtgaaaccg ttgggcaaga actggcgggt aacccaaagg tcgcaatggt cagtatgaca
    19501 ggcagcgtct ctgcaggtga gaagatcatg gcgactgcgg cgaaaaacat caccaaagtg
    19561 tgtctggaat tggggggtaa agcaccagct atcgtaatgg acgatgccga tcttgaactg
    19621 gcagtcaaag ccatcgttga ttcacgcgtc attaatagtg ggcaagtgtg taactgtgca
    19681 gaacgtgttt atgtacagaa aggcatttat gatcagttcg tcaatcggct gggtgaagcg
    19741 atgcaggcgg ttcaatttgg taaccccgct gaacgcaacg acattgcgat ggggccgttg
    19801 attaacgccg cggcgctgga aagggtcgag caaaaagtgg cgcgcgcagt agaagaaggg
    19861 gcgagagtgg cgttcggtgg caaagcggta gaggggaaag gatattatta tccgccgaca
    19921 ttgctgctgg atgttcgcca ggaaatgtcg attatgcatg aggaaacctt tggcccggtg
    19981 ctgccagttg tcgcatttga cacgctggaa gatgctatct caatggctaa tgacagtgat
    20041 tacggcctga cctcatcaat ctatacccaa aatctgaacg tcgcgatgaa agccattaaa
    20101 gggctgaagt ttggtgaaac ttacatcaac cgtgaaaact tcgaagctat gcaaggcttc
    20161 cacgccggat ggcgtaaatc cggtattggc ggcgcagatg gtaaacatgg cttgcatgaa
    20221 tatctgcaga cccaggtggt ttatttacag tcttaatgag tgaaagaggc ggaggttttt
    20281 tcctccgcct gtgcgcgtca gagtttagcg aatttttcga gggtgcgaat aagctgtgtg
    20341 acgaagccat attcgttatc gtaccaggcg accgttttca ccagttgtaa atcgcccacg
    20401 gcggtaattt ccgtttgcgt ggcatcaaac accgaaccga aatggctgcc aatgatatcg
    20461 gaagagacta tttcttcatc ggtataacca aatgactcgt tattggtggt tgcttgttta
    20521 agtgcgttat tcacctcttc ggcagtcact tttttccgag aatcgatacc agttcagtga
    20581 ccgaacctgt tttcaccggc acgcgttgcg catgaccttt cagtttgccg ctcagttccg
    20641 ggatcaccag accaatggct tttgccgccc ccgtagtgtg gggaatgata ttttctgccg
    20701 ctgcgcgtga agcacgtaaa tctttaccac gcgggccatc caccagtgac tgggtgccag
    20761 tataggcatg aatggtcgtc atcgtgccga cttctatccc gaaactgtca tgcaaggctt
    20821 tggccatcgg cgcaagacag ttagtggtgc atgacgccac ggaaacaatg gtgtcgttgc
    20881 catccagagt gtcgtcattg acgttataaa cgatagtttt catttcaccg gcaggggcgg
    20941 aaatcaacac cttcttcgca ccagcatcaa gatgcgcctg cgatttctcg gcggaggtat
    21001 aaaagccagt acattcgaca atgatttctg cacctttcgc tttccacgga atatttttag
    21061 cctctttttc ggcgtaaacc gcgatacttt tcccatcaac gataagtgaa tcttccgtaa
    21121 aatcaacgct ccaggggaat ggtccgtagt ttgaatcatg tttcagcagg taggcgagaa
    21181 tttatgggga agtgagatca ttaatagcga caacgtctat gttgcttttg acttcaagta
    21241 atcgacccaa caccagtcga ccgatacgac caaaaccgtt aataccaact ttactcatgg
    21301 ttttctcctg tcaggaacgt tcggatgaaa attgatcctt tccaggctta gaccaggatg
    21361 gcgggatggg caatctccat tctcacagtg aaacgtaacg tactgaaaac gggtgaacaa
    21421 tatttaatga aattttgaga aaagcccgtt atgttaacgg aaaattatgt taaagcagga
    21481 aatgttatgg aaaataaata ttcaaggtta caaatcagca ttcactggct ggtcttttta
    21541 ctggttatcg cagcgtattg cgcaatggag tttcgtggtt tcttcccacg tagcgatcgg
    21601 ccactcatca acatgattca tgtttcctgt ggcatctcaa ttctcgtgct gatggtcgtt
    21661 cgtcttttgt taaggctgaa atacccaacc ccgccgatta tacctaagcc aaaaccgatg
    21721 atgacgggac tggcgcattt gggacatttg gtgatttatc tcctgtttat tgcgctgcca
    21781 gtgattggtt tggtgatgat gtataaccgg ggcaacccgt ggtttgcgtt tggtttgacg
    21841 atgccttacg cttcagaggc caatttcgaa cgggtagata gcttaaagtc gtggcatgaa
    21901 acgctggcga atctgggata ttttgtcatc gggttgcacg ctgcggctgc actggcacac
    21961 cactatttct ggaaggacaa cacacttcta cgcatgatgc cgcgtaaacg ttcctgaagg
    22021 atatttaaag aaaacgcctg tactaaaacc gacccgtggt acaggcgaag aatacgggtc
    22081 tacatcggaa gcgcctatta tatttatttg tatgataaat aaaaccataa tccttgccca
    22141 tacgtccatc tggcttattt ttaatcaatt cacccgatct ttgatctcat caacggtatc
    22201 aaaataaacc agcgtataac gttcaaatcg aacataagat tcgataaacc atggaggtta
    22261 tatgaaaaaa ctggcactta ttttgtttat gggaacgctt gtttcctttt atgccgatgc
    22321 cgggcgcaaa ccctgttctg gttcgaaagg ggggatctca cactgtacgg caggcggcaa
    22381 atttgtctgt aatgatggtt ctattagtgc atcgaaaaaa acatgcacta actgaagtgt
    22441 aaaaggggtg ccatgagaaa atgaatctgc tagtcaaatg cgcggggaaa atccccgcgc
    22501 ttgcccttac ctggacgtgc aggccatgag cgcagcaacc tccttatcac cgtcccggaa
    22561 ccgcagttcg tagagcgttt gtcgggtcag gagtgtgaat gtcagaatcg taatgcagat
    22621 aatgagcaga cacaccacca gagggttgtg cttcatagcc tttctccttg ccggatggcg
    22681 ggtaagaggc taagatctga attgctaggt tcattcgttg gcctcggttg atagaaatat
    22741 cggtcggggc cttcgtcttt ctgattcccg gttagcctga aaacagaaag tctcaggcac
    22801 ccgcaggcat cctatgaggt ttccttaggg acgaaaataa tcacttcacg aaattgcgtg
    22861 ctgttttcca gaatttttcg tcattcgggt tagccagttt agccattcgt tactctcttc
    22921 attccaatag cattaatttt ctatgcaata attgttgtaa aaatgtgacg caaagaggtt
    22981 tttggtcata agtaattacc gtcaagtgcc gatgactttc tatcaggagt aaacctggac
    23041 gagagacaac ggtaatgaat acaactccct cacagcgatt aggttttttg catcacatca
    23101 ggttggttcc gttatttgcc tgcattctag gcggtatctt agttctattc gcattaagtt
    23161 cagccctggc tggctatttc ctctggcagg ccgatcgcga tcagcgtgat gttactgcgg
    23221 agattgagat tcggaccggg ttagcgaaca gttcagattt tttgcgttca gcccggatca
    23281 atatgattca ggccggggct gcgagtcgta ttgcggaaat ggaagcaatg aagcgaaata
    23341 ttgcgcaagc cgaatcggag attaaacagt cgcagcaagg ttatcgtgct tatcagaatc
    23401 gaccggtgaa aacacctgct gatgaagccc tcgacactga attaaatcaa cgctttcagg
    23461 cttatatcac gggtatgcaa cctatgttga aatatgccaa aaatggcatg tttgaagcga
    23521 ttatcaatca tgaaagtgag cagatccgac cgctggataa tgcttatacc gatattttga
    23581 acaaagccgt taagatacgt agcaccagag ccaaccaact ggcggaactg gcccatcagc
    23641 gcacccgcct gggtgggatg ttcatgattg gcgcgtttgt gcttgccctg gtcatgacgc
    23701 tgataacatt tatggtgcta cgtcggatcg tcattcgtcc actgcaacat gccgcacaac
    23761 ggattgaaaa aatcgccagt ggcgatctga cgatgaatga tgaaccggcg ggtcgtaatg
    23821 aaatcggtcg cttaagtcgt catttacagc aaatgcagca ttcactgggg atgacagtag
    23881 ggactgttcg acagggcgcg gaagagattt atcgtggcac cagcgaaatt tcagctggca
    23941 atgcggacct gtcatctcgc accgaagaac aagcggcggc tatcgaacaa actgccgcca
    24001 gcatggagca actcactgcg acggtgaaac agaatgcgga taacgcgcat catgccagca
    24061 aactggcgca agaggtttct attaaagcca gcgatggcgg gcagacggtt tccggtgtag
    24121 taaaaacgat gggcgctatc tccacgagtt cgaagaaaat ttctgagatc accgccgtca
    24181 tcaacagtat tgctttccag acgaatattc tggcactgaa tgctgccgtt gaagccgcgc
    24241 gagcgggtga gcaagggcgt ggatttgccg ttgtcgccag cgaagtacgg acactcgcaa
    24301 gtcgcagcgc tcaggcggcg aaagagattg aaggcttgat cagtgaatca gtcaggttaa
    24361 ttgacctggg gtcggatgag gtggcaacgg ccgggaaaac catgagcact attgttgatg
    24421 ccgtcgcgag tgtcacacat atcatgcagg aaatcgccgc cgcctcggat gaacaaagta
    24481 gaggcataac gcaggttagc caggcgattt ctgaaatgga taaggtgacg caacagaatg
    24541 cttctctggt agaagaggcc tcagcggcgg cggtgtccct tgaagaacag gcggcacgat
    24601 taactgaggc ggtggatgta ttccgtctgc acaaacattc tgtgtcggca gaacctcgcg
    24661 gagcgggtga accagttagt ttcgctacgg tgtgaaaatg ttcaaggagg gatcgacaga
    24721 tcccttcacc tttcagaacg gcattgattt tcgaatagcg ttaatcatca actggcaacc
    24781 agaagagaac gtcgcatcta cgcgggtcag tattccaatc ggttcgcctg caccatgtcc
    24841 cggaacaggc agggccacca gcgtggcatg acgcaggtcg tcttttacag cgccagaagg
    24901 gacaaaccac acgtaatcgt attcaaccgt aagttgacga gatagcgaag cagacagcgt
    24961 ttcgatacaa cccgaaggaa ttttacagcc ctggctctgc actaatgcat ctgaatgctg
    25021 gcgtggcgca gtgccttctg gtgatacaac gaccggccat tccagcaccc ggcttagcgt
    25081 tacgttctcc tgaagtagcg ggtgattagg gcggacaacc agcttcaacg attcaagaaa
    25141 cagcagttcg taattaagcc cggtcatcag ttcaggatct gacatccgac caatgccgat
    25201 atcgatttcc ccggttttta aacccgccag aatcataggg ttactcattg tcgcaacttg
    25261 caaggtcgtc tctttttgtt gctgatgaaa ctgacctata accgaaggta atatccccag
    25321 tgccgcagta ggtagtgcac caaccctgac gacatcatta ttaagacctt ctttacgatg
    25381 aagcgaccgt ccggcagtgt tgatggcgtc aagaactctg actgcatgcg ttaaaaattg
    25441 ttcgccgggt aaggtaagtt gcgccccctg acgaccacgc tcaaacaagc gagcgccagt
    25501 cagctgctcc agttcattca atgtcttaga gagcgcaggt tgactcaaat taagggtttc
    25561 agccgcgcgc cccaaagttc cttgttgtgc gacagctacg aatgtatgaa ggtggcgcaa
    25621 acggatgcgc tgactaaaca gactattttt ttccataagc gatgttaaaa acgaagcggt
    25681 gtcgctgaca agtgaagttg tttgattatg ataacttgat tgcaaaatat tattaacaat
    25741 taaagcaatt atgttacagc aaaatggata atattgatgt tttcgcggcg agatcacagt
    25801 ttgtaaattc ttcccgcaag agtgaatgcg gttacctaca ctccagatta ctgaccactg
    25861 gaggcagaca ctatggcgaa cagcatcacg gcggatgaga ttcgggaaca gttttcgcag
    25921 gcaatgtcag ccatgtacca gcaagaagtt ccgcaatatg gcacgctgct ggaactggta
    25981 gctgatgtga atctggctgt gctggaaaac aatcctcaac tgcacgaaaa aatggtaaat
    26041 gcagacgagc tggcgcgact gaatgttgaa cgtcatgggg cgattcgcgt tgggactgca
    26101 caagagcttg ctactcttcg gcggatgttt gccattatgg ggatgtaccc ggtgagctat
    26161 tacgatctct cgcaggcagg ggtgccggta cattcgacag catttcggcc cattgatgat
    26221 gcttctctgg cgcgtaatcc cttccgcgtt tttacctcct tactccgcct tgagcttatc
    26281 gagaacgaaa ttttgcgcca gaaagcggcg gagattctgc gtcagcgcga tatcttcacc
    26341 ccacgttgtc gacaactgtt agaggaatat gagcagcagg gcggttttaa cgaaacacag
    26401 gcacaggagt ttgtgcagga agccctggaa acgtttcgct ggcaccagtc agcaacggta
    26461 gatgaagaaa cctatcgcgc attgcacaac gaacatcggt tgattgctga tgtggtctgt
    26521 tttcctggat gccatatcaa ccacctgacg ccacgtacgc tggatattga ccgggtgcag
    26581 tcgatgatgc ctgaatgcgg aattgaaccc aaaattctca tcgaggggcc gccgcgccgc
    26641 gaggtaccga ttttactacg ccagaccagc tttaaagcac tggaagagac ggtgttgttt
    26701 gcggggcaga aacagggcac gcataccgcg cgctttggtg aaattgagca gcgtggcgtg
    26761 gcattaacgc cgaaagggcg acaactgtat gatgatcttc tgcgtaacgc tggaaccggg
    26821 caggataatc tcactcacca aatgcattta caggaaacct tccgcacttt tcctgacagt
    26881 gagtttttaa tgcgtcagca agggttggca tggttccggt accgtctgac gccttcgggt
    26941 gaggcgcatc gtcaggcgat tcatcctgga gacgatccac agcccttaat tgaacgtggt
    27001 tgggtagtgg cgcaacccat cacctatgaa gatttcttgc ccgttagcgc ggcggggatc
    27061 ttccagtcaa atctgggtaa tgaaacgcag acacgcagtc acggtaatgc cagtcgcgaa
    27121 gcatttgagc aggcgttggg ttgtccggtt ttggatgagt tccagcttta ccaggaagcg
    27181 gaagaacgca gtaaacgtcg ctgtggtttg ctttaaaatc tgaccatccg cctttgcaaa
    27241 aatttgcctg attttacaaa cgaatcaggc tcatcccatc gacataaaaa aaatgccgat
    27301 ttatgcatat tctctcagtt caacaattgg attattaata aatattgtct agagtgagcg
    27361 gtcataaata agcactttct tgccgctgaa aacgaccagc gcgggaccat tcacaacacc
    27421 agaaggactc actttcaggt atggatcgta gacgatttat taaaggttca atggctatgg
    27481 ccgccgtgtg cggtaccagc ggcattgctt ctcttttttc tcaggcggca ttcgcggcag
    27541 attctgatat tgccgacggg caaacccagc gttttgactt ctccattcta cagtcaatgg
    27601 cgcacgactt agcgcaaaca gcgtggcgtg gtgcgcctcg tccgttacct gacacgctgg
    27661 cgacaatgac gccgcaggct tataacagta ttcaatacga cgccgaaaaa tcgctctggc
    27721 ataacgttga gaaccgtcaa ctggacgctc agttcttcca tatgggaatg ggattccgtc
    27781 gccgcgttcg tatgttttct gtagatccag caacacatct ggcgcgtgaa attcactttc
    27841 gcccggagtt gttcaaatac aacgatgcag gtgttgatac aaaacaatta gaagggcaaa
    27901 gcgatctcgg ctttgccggt tttcgcgtgt ttaaagcccc cgaactggcg cgccgtgatg
    27961 tagtatcatt tctcggcgcg agttatttcc gcgccgttga tgatacatat caatacggtt
    28021 tgtcggcccg cggcctggcg atcgacactt acaccgacag taaagaagag ttccccgact
    28081 ttaccgcctt ctggtttgat acggtaaaac cgggggcaac tacctttacc gtttatgcgt
    28141 tgctcgatag cgccagcatt actggtgcct ataagttcac tatccattgt gagaaaagtc
    28201 aggtgattat ggatgtggaa aatcacctgt atgcgcgcaa agacattaaa cagctgggca
    28261 ttgcgccgat gaccagtatg ttcagctgcg gtactaatga acgtcggatg tgcgatacaa
    28321 ttcatccgca aattcatgac tctgatcgtc tgtccatgtg gcggggcaac ggcgagtgga
    28381 tttgccgtcc gctgaataat ccgcaaaaat tgcagttcaa tgcttacacc gacaacaacc
    28441 cgaaagggtt tggtttattg caactggatc gtgacttctc ccattatcag gacattatgg
    28501 gctggtataa caaacgccca agtctgtggg tggaaccgcg taacaagtgg ggtaagggca
    28561 ccatcggcct gatggaaatc ccaacaacgg gcgaaacgct ggataacatt gtctgcttct
    28621 ggcagccaga aaaagctgta aaagcaggtg atgagtttgc attccagtat cgtctgtact
    28681 ggagtgcgca accgcctgtt cattgcccat tagcgcgcgt tatggcgacg cgtaccggca
    28741 tgggcggttt ctcggaaggt tgggcgccag gtgaacacta tcccgaaaaa tgggcgcgtc
    28801 gttttgccgt cgatttcgtt ggtggtgatc tgaaagctgc cgcgccaaaa ggcattgagc
    28861 cggtgattac gctttccagt ggggaagcga agcaaatcga aattctctat attgaaccca
    28921 tcgatggtta tcgtattcag tttgactggt atccgacttc ggactccact gatccggtcg
    28981 atatgcggat gtatctacgt tgtcaggggg acgctatcag tgaaacatgg ctgtatcagt
    29041 atttcccgcc agcgccggat aaacgtcagt atgttgacga ccgcgtgatg agttaatcgt
    29101 tttttcttcg gcaccttctt cgggaggtgc cgtctggtta aacacgatcc cgctcgcatt
    29161 tttccctaag ttaaatgagt aatctgatgg tgtgtatttc agatacacct tgtcagccac
    29221 taacagggag tgcgtatgtt tccagaatac cgagatttaa tatcccgtct gaaaaacgaa
    29281 aatcctcgct ttatgtcctt gttcgataaa cacaataaac ttgatcatga aattgccaga
    29341 aaggaaggtt ccgacggtcg agggtacaat gcggaagtgg tccgcatgaa aaaacaaaag
    29401 ctacagttaa aagatgagat gctcaaaatc ctgcagcagg agagcgtcaa agaggtgtaa
    29461 actttcctaa gccgccagcc aggcggcttt tttaacaact gcatggattg actggagata
    29521 agatgactga aacgataaaa gtaagcgaat cacttgaatt acatgctgtt gcagaaaatc
    29581 acgtcaaacc tctttatcag ttaatctgta aaaataaaac ctggttacag cagtcgctaa
    29641 actggccgca gtttgttcaa agtgaagagg acacgcgaaa aacggtgcag ggtaatgtga
    29701 tgttgcatca acgcggctat gccaaaatgt tcatgatttt caaagaagat gaacttatcg
    29761 gcgttatctc gtttaatcgt attgaaccac tgaataaaac cgctgaaata ggctactggc
    29821 tggacgaatc tcatcagggg caggggatca tttctcaggc gctgcaggca ttgattcatc
    29881 attacgccca gtctggtgaa cttagacgct tcgtgatcaa atgtcgggtg gacaatccgc
    29941 aaagcaacca ggtcgctttg cgcaatggtt ttatccttga aggttgcctg aaacaggctg
    30001 agttcctgaa tgatgcctat gatgatgtga acttatacgc gcgtattatc gattcacaat
    30061 aaccctgcca gcggcgttcg cgtaatgcgc tcctcgccgt taatgacttt tggaccacgg
    30121 acatgaaccg tgtcgccatc aaaggcttca acgacggcgt ggtcggttaa ctccacatgg
    30181 ttttcaatta tcaccgcacc tgtaatacgg ctctcacctt gtatgacaac gtgctcgtcg
    30241 agcagaatcg gtccgccacg taccacggca tttccgccaa ccaagacatg atgttttaac
    30301 acacaattac cttccacaat ggcatattcc gccacctgcg aactgtaatg aatcgtcgga
    30361 atggcatctt cttctatgcc agctttcacc tgcgcgtgac cgtagacttt agcgcaatcg
    30421 catagccaga cattgttctc ttcattacct tcaatactgg caaaatcaaa aacttcggcg
    30481 cgatgttcaa taaaagcata ccggacgacg gcatcgccat aaatttgtgc ctggtggaca
    30541 atacgcgagg cgctaaccct tgcgcgatca taaatttgga gcaggagttg atggtcgggc
    30601 gttaagcctt gtgcggcgac gatcatagaa tgttgatcaa ttaaggcgtg accaaatatt
    30661 ctacattgcc cgtaaactaa tgagtcatga atggtgacgc tgtcacttat atatgcaccc
    30721 tggctgattt cactattatc gatccagacg ttatccgttg cgtaaacctc tccccacagc
    30781 acgctggtgc cggtgatacg cgtattaccg gaaatcaccg ctccgccgaa cgcaatagca
    30841 ttctggtcgt aaatccagca atttccttct tgtgctaaca ccgtttcgcg atcgatccag
    30901 ccgccagcgg ttcctgctat cacatcgtta aaatcgctaa tggcgataat ctgccgtaat
    30961 aacacatttt ttttagtgcc atcttcctga taactaaagg ctcgctgttc ttcacttaga
    31021 cgatatttgc gcatagcgtt ttcccacagg tgacttacta taaccgtagc aaattctgcg
    31081 gctctggcta tgctcgagaa aattcca
//
LOCUS       DAPOAV010000051        30224 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.051, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000051 DAPOAV010000000
VERSION     DAPOAV010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 30224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30224
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.051"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(11..259)
                     /gene="hybG"
                     /locus_tag="RN951_002617"
     CDS             complement(11..259)
                     /gene="hybG"
                     /locus_tag="RN951_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation factor HybG"
                     /protein_id="HDX2527598.1"
                     /translation="MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADL
                     LGQWVLVHVGFAMSIIDEDEAKATLDALRQMDYDITSA"
     gene            complement(272..613)
                     /gene="hypA"
                     /locus_tag="RN951_002618"
     CDS             complement(272..613)
                     /gene="hypA"
                     /locus_tag="RN951_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HDX2527599.1"
                     /translation="MHELSLCQSAVEIIQRQAEQHDVKRVTAVWLEIGALSCVEESAV
                     RFSFEIVCHGTVAQGCDLHIVYKPAQAWCWDCSQVVEIHQHDAQCPLCHGERLRVDTG
                     DSLIVKSIEVE"
     gene            complement(606..1094)
                     /gene="hybE"
                     /locus_tag="RN951_002619"
     CDS             complement(606..1094)
                     /gene="hybE"
                     /locus_tag="RN951_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-2 assembly chaperone"
                     /protein_id="HDX2527600.1"
                     /translation="MTEEIAGFQTSPKAQVQAAFEEIARRSMHDLSFLHPSMPVYVSD
                     FTLFEGQWTGCVITPWMLSAVIFPGPDQLWPLRKVSEKIGLQLPYGTMTFTVGELDGV
                     SQYLSCSLMSPLSHSMSIEEGQRLTDDCARMILSLPVTNPDVPHAGRRALLFGRRSGE
                     NA"
     gene            complement(1087..1581)
                     /locus_tag="RN951_002620"
     CDS             complement(1087..1581)
                     /locus_tag="RN951_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HyaD/HybD family hydrogenase maturation
                     endopeptidase"
                     /protein_id="HDX2527601.1"
                     /translation="MRILVLGVGNILLTDEAIGVRIVEALEQRYILPDYVEILDGGTA
                     GMELLGDMANRDHLIIADAIVSKKSAPGTMMILRDEEVPALFTNKISPHQLGLADVLS
                     ALRFTGEFPKKLTLVGVIPESLEPHIGLTPTVEAMIEPALEQVLAALRESGVEAIPRE
                     AIHD"
     gene            complement(1581..3284)
                     /gene="hybC"
                     /locus_tag="RN951_002621"
     CDS             complement(1581..3284)
                     /gene="hybC"
                     /locus_tag="RN951_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 large subunit"
                     /protein_id="HDX2527602.1"
                     /translation="MSQRITIDPVTRIEGHLRIDCEIENGVVSKAWASGTMWRGMEEI
                     VKNRDPRDAWMIVQRICGVCTTTHALSSVRAAESALNIDVPVNAQYIRNIILAAHTTH
                     DHIVHFYQLSALDWVDITSALQADPTKASEMLKGVSTWHLNSPEEFTKVQNKIKDLVA
                     SGQLGIFANGYWGHPAMKLPPEVNLIAVAHYLQALECQRDANRVVALLGGKTPHIQNL
                     AVGGVANPINLDGLGVLNLERLMYIKSFIDKLSDFVEQVYKVDTAVIAAFYPEWLTRG
                     KGAVNYLSVPEFPTDSKNGSFLFPGGYIENADLSSYRPITSHSDEYLIKGIQESAKHS
                     WYKDEAPQAPWEGTTIPAYDGWSDDGKYSWVKSPTFYGKTVEVGPLANMLVKLAAGRE
                     STQNKLNEIVAIYQKLTGNTLEVAQLHSTLGRIIGRTVHCCELQDILQNQYSALITNI
                     GKGDHTTFVKPNIPATGEFKGVGFLEAPRGMLSHWMVIKDGIISNYQAVVPSTWNSGP
                     RNFNDDVGPYEQSLVGTPVADPNKPLEVVRTIHSFDPCMACAVHVVDADGNEVVSVKV
                     L"
     gene            complement(3281..4459)
                     /gene="hybB"
                     /locus_tag="RN951_002622"
     CDS             complement(3281..4459)
                     /gene="hybB"
                     /locus_tag="RN951_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase cytochrome b subunit"
                     /protein_id="HDX2527603.1"
                     /translation="MSHDPQPLGGKIISKPVMIFGPLIVICMLLIVKRLVFGLGSVSD
                     LNGGFPWGVWIAFDLLIGTGFACGGWALAWAVYVFNRGQYHPLVRPALLASLFGYSLG
                     GLSITIDVGRYWNLPYFYIPGHFNVNSVLFETAVCMTIYIGVMALEFAPALFERLGWK
                     VSLKRLNKVMFFIIALGALLPTMHQSSMGSLMISAGYKVHPLWQSYEMLPLFSLLTAF
                     IMGFSIVIFEGSLVQAGLRGNGPDEKSLFVKLTNTISVLLAIFIVLRFGELIYRDKLS
                     LAFAGDFYSVMFWIEVLLMLFPLVVLRVAKLRNDSRMLFLSALSALLGCATWRLTYSL
                     VAFNPGGGYAYFPTWEELLISIGFVAIEICAYIVLIRLLPILPPLKQNDHNRHEASKA
                     "
     gene            complement(4449..5435)
                     /gene="hybA"
                     /locus_tag="RN951_002623"
     CDS             complement(4449..5435)
                     /gene="hybA"
                     /locus_tag="RN951_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 operon protein HybA"
                     /protein_id="HDX2527604.1"
                     /translation="MNRRNFIKAASCGALLTGALPSVSHAAAENRPPIPGSLGMLYDS
                     TLCVGCQACVTKCQDINFPERNPQGEQTWSNNDKLSPYTNNIIQVWTSGTGVNKDQEE
                     NGYAYIKKQCMHCVDPNCVSVCPVSALKKDPKTGIVHYDKDVCTGCRYCMVACPYNVP
                     KYDYNNPFGALHKCELCNQKGVERLDKGGLPGCVEVCPAGAVIFGTREELMAEAKKRL
                     ALKPGSEYHYPRQTLKSGDTYLHTVPKYYPHLYGEKEGGGTQVLVLTGVPYENLDLPK
                     LDDLSTGARSENIQHTLYKGMMLPLAVLAGLTVLVRRNTKNDHHDGGDDHES"
     gene            complement(5438..6556)
                     /gene="hybO"
                     /locus_tag="RN951_002624"
     CDS             complement(5438..6556)
                     /gene="hybO"
                     /locus_tag="RN951_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 small subunit"
                     /protein_id="HDX2527605.1"
                     /translation="MTGDNTLIHSHGINRRDFMKLCAALAATMGLSSKAAAEMAESVT
                     NPQRPPVIWIGAQECTGCTESLLRATHPTVENLVLETISLEYHEVLSAAFGHQVEENK
                     HNALEKYKGQYVLVVDGSIPLKDNGIYCMVAGEPIVDHIRKAAEGAAAIIAIGSCSAW
                     GGVAAAGVNPTGAVSLQEVLPGKTVINIPGCPPNPHNFLATVAHIITYGKPPKLDDKN
                     RPTFAYGRLIHEHCERRPHFDAGRFAKEFGDEGHREGWCLYHLGCKGPETYGNCSTLQ
                     FCDVGGVWPVAIGHPCYGCNEEGIGFHKGIHQLANVENQTPRSQKPDVNAKEGGNVSA
                     GAIGLLGGVVGLVAGVSVMAVRELGRQQKKDNADSRGE"
     gene            complement(6745..7032)
                     /locus_tag="RN951_002625"
     CDS             complement(6745..7032)
                     /locus_tag="RN951_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2623 domain-containing protein"
                     /protein_id="HDX2527606.1"
                     /translation="MNNHFGKGLMAGLKATHADSAVNVTKFCADYKRGFVLGYSHRMY
                     EKTGDRQLSAWEAGILTRRYGLDKEMVMDFFRENNSCSTLRFFMAGYRLEN"
     gene            complement(7151..8038)
                     /locus_tag="RN951_002626"
     CDS             complement(7151..8038)
                     /locus_tag="RN951_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311911.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HDX2527607.1"
                     /translation="MPRLTAKDFPQELLDYYDYYAHGKISKREFLNLAAKYAVGGMTA
                     LALFDLLKPNYALATQVEFTDPEIVAEYITYPSPNGHGEVRGYLVKPAKMSGKTPAVV
                     VVHENRGLNPYIEDVARRVAKAGYIALAPDGLSSVGGYPGNDDKGRELQQQVDPTKLM
                     NDFFAAIEFMQRYPQAAGKVGITGFCYGGGVSNAAAVAYPELACAVPFYGRQAPTADV
                     AKIEAPLLLHFAELDTRINEGWPAYEAALKANNKVYEAYIYPGVNHGFHNDSTPRYDK
                     SAADLAWQRTLKWFDKYLS"
     gene            8195..9235
                     /gene="gpr"
                     /locus_tag="RN951_002627"
     CDS             8195..9235
                     /gene="gpr"
                     /locus_tag="RN951_002627"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HDX2527608.1"
                     /translation="MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALES
                     QRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDM
                     WPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
                     KALYVGISSYSPERTQKMVELLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVG
                     CIAFTPLAQGLLTGKYLNGIPQDSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQ
                     RGQSMAQMALSWLLKDDRVTSVLIGASRAEQLEENVQALNNLTFSTKELAQIDQHIAD
                     GELNLWQASSDK"
     gene            complement(9275..9769)
                     /locus_tag="RN951_002628"
     CDS             complement(9275..9769)
                     /locus_tag="RN951_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00645 family protein"
                     /protein_id="HDX2527609.1"
                     /translation="MERFLENAMYASRWLLAPVYFGLSLALVALALKFFQEIIHVLPN
                     IFSMAESDLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISENKEKLNWLGKMDA
                     TSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLT
                     RHNH"
     gene            9960..10844
                     /gene="yghA"
                     /locus_tag="RN951_002629"
     CDS             9960..10844
                     /gene="yghA"
                     /locus_tag="RN951_002629"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(+)-dependent aldehyde reductase"
                     /protein_id="HDX2527610.1"
                     /translation="MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGS
                     GRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKA
                     VLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAIN
                     VFALFWLTQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVA
                     EKGIRVNIVAPGPIWTALQISGGQTQDKIPQFGQKTPMKRAGQPAELAPVYVYLASQE
                     SSYVTAEVHGVCGGEHLG"
     gene            complement(11116..11541)
                     /gene="exbD"
                     /locus_tag="RN951_002630"
     CDS             complement(11116..11541)
                     /gene="exbD"
                     /locus_tag="RN951_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein ExbD"
                     /protein_id="HDX2527611.1"
                     /translation="MAMHLNENLDDNGEMHDINVTPFIDVMLVLLIIFMVAAPLATVD
                     VKVNLPASTSTPQPRPEKPVYLSVKADNSMFIGNDPVTDETMITALNALTEGKKDTTI
                     FFRADKTVDYETLMKVMDTLHQAGYLKIGLVGEETAKAK"
     gene            complement(11548..12282)
                     /gene="exbB"
                     /locus_tag="RN951_002631"
     CDS             complement(11548..12282)
                     /gene="exbB"
                     /locus_tag="RN951_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
                     /protein_id="HDX2527612.1"
                     /translation="MGNNLMQTDLSVWGMYQHADIVVKCVMIGLILASVVTWAIFFSK
                     SVEFFNQKRRLKREQQLLAEARSLNQANDIAADFGSKSLSLHLLNEAQNELELSEGSD
                     DNEGIKERTSFRLERRVAAVGRQMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIA
                     QTQTTNLAVVAPGIAEALLATAIGLVAAIPAVVIYNVFARQIGGFKAMLGDVAAQVLL
                     LQSRDLDLEASAAAHPVRVAQKLRAG"
     gene            12534..13721
                     /gene="metC"
                     /locus_tag="RN951_002632"
     CDS             12534..13721
                     /gene="metC"
                     /locus_tag="RN951_002632"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HDX2527613.1"
                     /translation="MADKKLDTQLVNAGRSKKYTLGAVNSVIQRASSLVFDSVEAKKH
                     ATRNRANGELFYGRRGTLTHFSLQQAMCELEGGAGCVLFPCGAAAVANSILAFVEQGD
                     HVLMTNTAYEPSQDFCSKILSKLGVTTSWFDPLIGADIVKHLQPNTKIVFLESPGSIT
                     MEVHDVPAIVAAVRSVVPDAIIMIDNTWAAGVLFKALDFGIDVSIQAATKYLVGHSDA
                     MIGTAVCNARCWEQLRENAYLMGQMVDADTAYITSRGLRTLGVRLRQHHESSLKVAEW
                     LAEHPQVARVNHPALPGSKGHEFWKRDFTGSSGLFSFVLKKKLSNEELANYLDNFSLF
                     SMAYSWGGYESLILANQPEHIAAIRPQGEIDFSGTLIRLHIGLEDVDDLIADLDAGFA
                     RIV"
     gene            13861..14520
                     /locus_tag="RN951_002633"
     CDS             13861..14520
                     /locus_tag="RN951_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDX2527614.1"
                     /translation="MAVIQDIIAALWQHDFAALADPHIVSVVYFVMFATLFLENGLLP
                     ASFLPGDSLLILAGALIAQGVMDFLPTIAILTAAASLGCWLSYIQGRWLGNTKTVKGW
                     LAQLPAKYHQRATCMFDRHGLLALLAGRFLAFVRTLLPTMAGISGLPNRRFQFFNWLS
                     GLLWVSVVTSFGYALSMIPFVKRHEDQVMTFLMILPIALLTAGLLGTLFVVIKKKYCN
                     A"
     gene            complement(14560..15459)
                     /gene="yqhC"
                     /locus_tag="RN951_002634"
     CDS             complement(14560..15459)
                     /gene="yqhC"
                     /locus_tag="RN951_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001407451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YqhC"
                     /protein_id="HDX2527615.1"
                     /translation="MKREEICRLLADKVNKLKIKENSLSELLPDVRLLYGETPFARTP
                     VMYEPGIIILFSGHKIGYINERVFRYDANEYLLLTVPLPFECETYATSEVPLAGLRLN
                     VDILQLQELLMDIGEDEHFQPSMAASGINSATLSEEILCAAERLLDVMERPLDARILG
                     KQIIREILYYVLTGPCGGALLALVSRQTHFSLISRVLKRIENKYTENLSVEQLAAEAN
                     MSVSAFHHNFKSVTSTSPLQYLKNYRLHKARMMIIHDGMKASAAAMRVGYESASQFSR
                     EFKRYFGVTPGEDAARMRAMQGN"
     gene            15653..16816
                     /gene="yqhD"
                     /locus_tag="RN951_002635"
     CDS             15653..16816
                     /gene="yqhD"
                     /locus_tag="RN951_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HDX2527616.1"
                     /translation="MNNFNLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKT
                     GVLDQVLDALKGMDVLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTK
                     FIAAAANYPENIDPWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDK
                     QAFHSAHVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAE
                     GILLTLIEDGPKALKEPENYDVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAM
                     HGLDHAQTLAIVLPALWNEKRETKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFF
                     EQLGVPTHLSDYGLDGSSIPALLKKLEEHGMTQLGENHDITLDVSRRIYEAAR"
     gene            16921..17748
                     /gene="dkgA"
                     /locus_tag="RN951_002636"
     CDS             16921..17748
                     /gene="dkgA"
                     /locus_tag="RN951_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417485.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgA"
                     /protein_id="HDX2527617.1"
                     /translation="MANPTVIKLQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRS
                     IDTAAAYKNEEGVGKALKNASVNREELFITTKLWNDDHKRPREALLDSLKKLQLDYID
                     LYLMHWPVPAIDHYVEAWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVINQ
                     IELHPLMQQRQLHAWNATHKIQTESWSPLAQGGKGVFDQKVIRDLADKYGKTPAQIVI
                     RWHLDSGLVVIPKSVTPSRIAENFDVWDFRLDKDELGEIAKLDQGKRLGPDPDQFGG"
     gene            17948..18874
                     /locus_tag="RN951_002637"
     CDS             17948..18874
                     /locus_tag="RN951_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjP/YqhG family protein"
                     /protein_id="HDX2527618.1"
                     /translation="MKIILLFLAALASFTVHAQPPSLTVEQTVRHIYQNYKSDATAPY
                     FGETGERAITSARIQQALTLNDNLTLPGNIGWLDYDPVCDCQDFGDLVLESVAITQTD
                     ADHADAVVRFRIFKDDKEKTTQTLKMVAENGRWVIDDIVSNHGSVLQAVNSENEKTLA
                     ALASLQKEQPEAFVAELFEHIADYSWPWTWVVSDSYRQAVNAFYKTTFKTANNPDEDM
                     QIERQFIYDNPICFGEESLFSRVDEIRVLEKTADSARIHVRFTLTNGNNEEQELVLQR
                     REGKWEIADFIRPNSGSLLKQIEAKTAARLKQ"
     gene            18925..19182
                     /gene="yqhH"
                     /locus_tag="RN951_002638"
     CDS             18925..19182
                     /gene="yqhH"
                     /locus_tag="RN951_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein YqhH"
                     /protein_id="HDX2527619.1"
                     /translation="MKTIFTVGAVVLATCLLSGCVNEQKVNQLASNVQTLNAKIARLE
                     QDMKALRPQIYAAKSEANRANTRLDAQDYFDCLRCLRMYAE"
     gene            complement(19225..21444)
                     /locus_tag="RN951_002639"
     CDS             complement(19225..21444)
                     /locus_tag="RN951_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HDX2527620.1"
                     /translation="MSSISLIQPDRDLFSWPQYWAACFGPAPFLPMSREEMDQLGWDS
                     CDIILVTGDAYVDHPSFGMAICGRMLEAQGFRVGIIAQPDWSSKDDFMRLGKPNLFFG
                     VTAGNMDSMINRYTADRRLRHDDAYTPDNVAGKRPDRATLVYTQRCKEAWKDVPVILG
                     GIEASLRRTAHYDYWSDTVRRSVLVDSKADMLMFGNGERPLVEVAHRLAMGEPISEIR
                     DVRNTAIIVKEALPGWSGVDSTRLDTPGKIDPIPHPYGEDLPCADNKPVAPKKQEAKA
                     VTVQPPRPKPWEKTYVLLPSFEKVKGDKVLYAHASRILHHETNPGCARALMQKHGDRY
                     VWINPPAIPLSTEEMDSVFALPYKRVPHPAYGNARIPAYEMIRFSVNIMRGCFGGCSF
                     CSITEHEGRIIQSRSEDSIINEIEAIRDTVPGFTGVISDLGGPTANMYMLRCKSPRAE
                     QTCRRLSCVYPDICPHMDTNHEPTINLYRRARDLKGIKKILIASGVRYDIAVEDPRYI
                     KELATHHVGGYLKIAPEHTEEGPLSKMMKPGMGSYDRFKELFDTYSKQAGKEQYLIPY
                     FISAHPGTRDEDMVNLALWLKKHRFRLDQVQNFYPSPLANSTTMYYTGKNPLAKIGYK
                     SEDVFVPKGDKQRRLHKALLRYHDPANWPLIRQALEAMGKKHLIGSRRDCLVPAPTIE
                     EMREARRQNRNTRPALTKHTPMATQRQTPATAKKASSTQSRPVNAGAKKRPKAAVGR"
     gene            complement(21555..22967)
                     /gene="ftsP"
                     /locus_tag="RN951_002640"
     CDS             complement(21555..22967)
                     /gene="ftsP"
                     /locus_tag="RN951_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsP"
                     /protein_id="HDX2527621.1"
                     /translation="MSLSRRQFIQASGIALCAGAVPLKASAAGQQQPLPVPPLLESRR
                     GQPLFMTVQRAHWSFTPGTRASVWGINGRYLGPTIRVWKGDDVKLIYSNRLTENVSMT
                     VAGLQVPGPLMGGPARMMSPNADWAPVLPIRQNAATLWYHANTPNRTAQQVYNGLAGM
                     WLVEDEVSKSLPIPNHYGVDDFPVIIQDKRLDNFGTPEYNEPGSGGFVGDTLLVNGVQ
                     SPYVEVSRGWVRLRLLNASNSRRYQLQMSDGRPLHVISGDQGFLPAPVSVKQLSLAPG
                     ERREILVDMSNGDEVSITCGEAASIVDRIRGFFEPSSILVSTLVLTLRPTGLLPLVTD
                     SLPMRLLPTEIMAGSPIRSRDISLGDDPGINGQLWDVNRIDVTAQQGTWERWTVRADE
                     PQAFHIEGVMFQIRNVNGAMPFPEDRGWKDTVWVDGQVELLVYFGQPSWAHFPFYFNS
                     QTLEMADRGSIGQLLVNPVP"
     gene            complement(23042..23779)
                     /gene="plsC"
                     /locus_tag="RN951_002641"
                     /gene_synonym="parF"
     CDS             complement(23042..23779)
                     /gene="plsC"
                     /locus_tag="RN951_002641"
                     /gene_synonym="parF"
                     /EC_number="2.3.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acylglycerol-3-phosphate O-acyltransferase"
                     /protein_id="HDX2527622.1"
                     /translation="MLYIFRLIITVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGR
                     LAPLFGLKVECRKPADAESYGNAIYIANHQNNYDMVTASNIVQPPTVTVGKKSLLWIP
                     FFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLPFK
                     TGAFHAAIAAGVPIIPVCVSTTSNKINLNRLHNGLVIVEMLPPIDVSQYGKDQVRELA
                     AHCRSIMEQKIAELDKEVAEREAAGKV"
     gene            complement(24013..26271)
                     /gene="parC"
                     /locus_tag="RN951_002642"
     CDS             complement(24013..26271)
                     /gene="parC"
                     /locus_tag="RN951_002642"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HDX2527623.1"
                     /translation="MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRR
                     IVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDIACYEAMVLMAQPFSYRYPLVDG
                     QGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR
                     LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTE
                     AEIITSRAEIRKIYENGRGSVRMRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRN
                     KKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGL
                     DGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEI
                     IRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSEREKERDQLQGI
                     LASERKMNNLLKKELQADAQAYGDDRRSPLQEREEAKAMSEHDMLPSEPVTIVLSQMG
                     WVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSARGQ
                     GEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITL
                     PENAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARG
                     EDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDRVEID
                     SPRRASSGDSEE"
     gene            complement(26817..27299)
                     /locus_tag="RN951_002643"
     CDS             complement(26817..27299)
                     /locus_tag="RN951_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDX2527624.1"
                     /translation="MTNLTLDVNIIDFPSIPVAMLPHRCSPELLNYSVAKFIMWRKET
                     GLSPVNQSQTFGVAWDDPATTAPEAFRFDICGSVSEPIPDNRYGVSNGELTGGRYAVA
                     RHVGELDDISHTIWGIIRHWLPASGEKMRKAPILFHYTNLAEGVTEQRLETDVYVPLA
                     "
     gene            complement(27352..27744)
                     /gene="ygiW"
                     /locus_tag="RN951_002644"
     CDS             complement(27352..27744)
                     /gene="ygiW"
                     /locus_tag="RN951_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OB fold stress tolerance protein YgiW"
                     /protein_id="HDX2527625.1"
                     /translation="MKKFAAVIAVMALCSAPVMAAEQGGFSGPSATQSQAGGFQGPNG
                     SVTTVESAKSLRDDTWVTLRGNIVERISDDLYVFKDASGTINVDIDHKRWNGVTVTPK
                     DTVEIQGEVDKDWNSVEIDVKQIRKVNP"
     gene            27896..28555
                     /gene="qseB"
                     /locus_tag="RN951_002645"
     CDS             27896..28555
                     /gene="qseB"
                     /locus_tag="RN951_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator QseB"
                     /protein_id="HDX2527626.1"
                     /translation="MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAP
                     YDAVILDLTLPGMDGRDILREWREKGQREPVLILTARDALEERVEGLRLGADDYLCKP
                     FALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
                     LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGE
                     K"
     gene            28552..29901
                     /gene="qseC"
                     /locus_tag="RN951_002646"
     CDS             28552..29901
                     /gene="qseC"
                     /locus_tag="RN951_002646"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_306641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     QseC"
                     /protein_id="HDX2527627.1"
                     /translation="MKFTQRLSLRVRLTLIFLILASVTWLLSSFVAWKQTTDNVDELF
                     DTQLMLFAKRLSTLDLNEINAADRMAQTPNKLKHGHVDDDALTFAIFTHDGRMVLNDG
                     DNGEDIPYSYQREGFADGQLVGDKDQWRFVWMTSPDGKYRIVVGQEWEYREDMALAIV
                     AGQLIPWLVALPIMLIIMMVLLGRELAPLNKLALALRMRDPDSEKPLNATGVPSEVRP
                     LVESLNQLFARTHAMMVRERRFTSDAAHELRSPLTALKVQTEVAQLSDDDPQARKKAL
                     LQLHYGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSSVMDIYHTAQQAKID
                     VRLTLNAHGIKRTGQPLLLSLLVRNLLDNAVRYSPQGSVIDVTLNADNFIVRDNGPGV
                     TPEALARIGERFYRPPGQTATGSGLGLSIVQRIAKLHGMNVEFGNAEQGGFEAKVSW"
     gene            complement(29947..>30224)
                     /locus_tag="RN951_002647"
     CDS             complement(29947..>30224)
                     /locus_tag="RN951_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF2645 family protein"
                     /protein_id="HDX2527628.1"
                     /translation="YWLIDAFFAFNKYDWMLESGDNICSIPSVSGEDRILQAMIAAFF
                     LLTPLIILILRKLFMREMFEFWVYVFSLGICLVCGWWLFWGRFIFCY"
BASE COUNT         7453 a         8086 c         7642 g         7043 t
ORIGIN      
        1 aagctaatca tcacgcgctg gtaatgtcgt aatccatttg gcgcagtgcg tctaatgtgg
       61 ctttggcttc atcttcgtcg atgatgctca tggcaaatcc gacgtgtacc agcacccact
      121 ggcccagtag atcggcaggg ttaccttcac aaatcagggc gatattcaca tcgcgcttga
      181 taccacatac ttcaacctgc gcaagctggt gaatatcttc accgacagcc agcacctggc
      241 ctggaacgcc aatacacatt attaactccg gttattcaac ttcaatactt ttgacgatca
      301 gcgaatcgcc ggtatcgaca cgcaaccgct cgccgtgaca gagcggacac tgcgcatcgt
      361 gctgatgaat ctccaccacc tggctgcaat cccagcacca agcctgggcg ggtttataga
      421 cgatatgtaa atcgcaccct tgcgccaccg ttccgtggca gacaatttca aaactaaaac
      481 ggacggcgct ctcctcaacg caggagagcg cgccaatttc cagccacacg gcggtgacgc
      541 gcttaacatc gtgctgctcc gcctgccgtt ggataatttc aacggcgctc tggcaaagcg
      601 acaactcatg cattttcgcc actcctgcga ccaaacagca gggcgcgacg ccctgcgtgt
      661 ggtacatccg gattcgtgac tggcagcgaa aggatcattc gtgcgcagtc atccgtcaga
      721 cgttggccct cttcaatcga catactgtgc gaaagcggtg acatcagcga acaggagagg
      781 tattgcgaaa caccgtccag ttcgccaacg gtaaaggtca tggtgccata cggcagttgc
      841 agaccaattt tttcactcac tttgcgcagc ggccagagtt gatccgggcc ggggaagata
      901 actgcactca gcatccacgg ggtgatcaca caccccgtcc actgaccttc gaacagcgta
      961 aaatcagaaa catacaccgg cattgaagga tgcagaaaag agagatcgtg catcgaacgc
     1021 cgggcaattt cttcaaacgc tgcctgtact tgcgccttcg gggaggtctg gaaacctgct
     1081 atctcttcag tcatgaatcg cctcccgtgg gatggcttcc acgcctgatt cgcgcagcgc
     1141 agccagaacc tgctcaagcg caggttcaat cattgcttca accgtcggcg ttaagccgat
     1201 gtgtggctcc agcgattccg ggatcacgcc gaccagggtc agctttttcg gaaactcgcc
     1261 ggtgaagcgc agggccgaca agacgtcggc caggccaagc tgatgcggag agattttgtt
     1321 ggtaaacaac gccggaactt cttcatcccg caggatcatc atcgttcccg gcgcgctctt
     1381 cttcgacaca atggcatccg caataatcag atgatcgcga tttgccatgt cgccaagcag
     1441 ctccattccc gccgtgccgc catcgaggat ctcaacataa tccggcagaa tgtatcgttg
     1501 ctctaacgct tcgacaatcc gcacaccgat ggcttcatcg gtcagcaaaa tattgccgac
     1561 ccctaagact aaaatacgca ttacagaacc ttcactgaaa ccacttcgtt gccgtcggca
     1621 tccactacgt gtaccgcaca ggccatgcac gggtcgaagg agtgaatggt acgcaccact
     1681 tccagcggtt tattcggatc agcaaccggt gtacccacca gcgactgctc gtaaggaccg
     1741 acgtcatcat tgaagttacg cggaccagag ttccaggttg atggaacaac tgcctggtag
     1801 ttgctgatga taccgtcttt gatcaccatc cagtgagaga gcataccgcg cggcgcttcg
     1861 aggaagccaa cacctttgaa ctcacccgtt gccggaatgt tcggcttcac aaaggtggta
     1921 tgatcgcctt taccgatatt ggtgatcagt gcactgtatt gattttgcag gatatcctgc
     1981 aattcgcagc agtgaacggt acgaccaata atacggccca gcgtagagtg cagctgtgcc
     2041 acttcaagcg tgttaccagt cagtttctga taaatcgcaa cgatttcatt cagtttgttc
     2101 tgggtagact cgcgtcctgc cgccagtttc accagcatgt tagccagcgg acccacttct
     2161 accgttttgc cgtagaaagt cggtgatttc acccaggaat atttcccgtc gtcagaccaa
     2221 ccatcataag ccggaatggt ggtaccttcc cacggcgcct gtggcgcttc gtctttatac
     2281 caggagtgct tcgcgctttc ctgaatgcct ttgatcaggt attcatcgga atgagaagtg
     2341 atcggacgat acgaggacag atccgcattc tcaatgtagc cgcccgggaa caggaagctg
     2401 ccgtttttgc tgtcggtcgg gaattccggc acgctcaggt agttcaccgc acctttaccg
     2461 cgcgtcagcc attccgggta gaacgcggcg ataaccgcgg tatcaacctt ataaacctgc
     2521 tcaacaaagt cgctcagttt gtcgatgaaa gacttgatgt acatcaggcg ctcaaggttc
     2581 aacacgccca acccgtcgag gttgattggg ttcgcgacac cacccactgc caggttctga
     2641 atgtgcggcg ttttaccgcc cagcagcgcc acgacgcggt tagcgtcacg ctggcactcc
     2701 agcgcctgca ggtagtgcgc taccgcaatc aggttcactt ccggcggcag tttcatcgct
     2761 gggtgacccc agtagccatt agcgaaaata cccaactgac cgctggcaac cagatctttg
     2821 atcttgttct gaactttggt gaactcttcc gggctgttca gatgccaggt cgaaacgcct
     2881 ttcagcattt cggaggcttt ggttgggtca gcttgcagtg cagaagtgat atccacccag
     2941 tccagcgccg aaagctgata gaaatgaacg atatggtcat gcgtggtgtg cgcagccaga
     3001 atgatgttac ggatgtattg cgcgttaacc ggaacgtcga tattcagcgc actttctgcc
     3061 gcacgaacgg aagacagcgc gtgagtggta gtacatacgc cacagatacg ttgcacaatc
     3121 atccatgcat cgcgcggatc gcggtttttc acgatctctt ccatgccgcg ccacatggta
     3181 ccggaagccc atgctttcga aacgacgcca ttttcgattt cgcaatcgat gcgtaaatgc
     3241 ccctcaatac gggttaccgg atcaatagta attctctggc tcatgctttg ctcgcctcat
     3301 gacgattatg atcgttttgt tttaaaggag gaagtatcgg cagtagacga atgagtacga
     3361 tgtaagcgca aatctcaata gccacaaaac caatagaaat caacagttct tcccaggtcg
     3421 ggaagtaggc gtaaccgccg cccgggttga atgccaccag cgaataggtc agacgccagg
     3481 ttgcacaacc taacagtgcg ctcagtgctg acaggaacag catgcgggaa tcattacgca
     3541 gcttcgccac acgcagaacc accagcggga agagcatcag caggacttca atccagaaca
     3601 tcacggagta gaagtcaccg gcaaacgcta acgacagctt gtcgcgatag ataagctcgc
     3661 caaagcgcag cacgatgaaa atcgccagca acacactgat ggtgttggtc agcttgacga
     3721 acagactctt ttcatccgga ccgttgccac gcagacccgc ctgcaccagc gaaccttcaa
     3781 agatgacaat cgagaagccc atgatgaacg ccgtcagcag cgagaacagc ggcaacattt
     3841 catagctctg ccacaacgga tgcaccttgt agcccgccga gatcatcagt gaccccattg
     3901 aagactggtg catggtcggc aacagcgcgc caagtgcaat gatgaagaac atcaccttgt
     3961 tcagacgctt gagagaaacc ttccagccca gacgttcaaa cagtgccgga gcaaactcca
     4021 gtgccatcac gccgatatag atggtcatac agaccgccgt ctcgaacagt accgagttca
     4081 cgttgaagtg acccggaatg tagaagtacg gcaggttcca gtagcgaccc acgtcgatag
     4141 tgatcgacaa gccccccagt gagtaaccaa acagactcgc caacagcgcc ggacgcacca
     4201 gcggatggta ttgcccacgg ttaaagacgt ataccgccca cgccagcgcc cagccgccac
     4261 aggcaaagcc ggtaccaatc agcaggtcaa acgcgatcca cacgccccac gggaagccgc
     4321 cgttcaggtc agagacagag cccagaccga acaccagacg cttcacaatc aggagcatac
     4381 agatgacgat taacggtcca aaaatcatga ccggtttact gatgattttg ccgcccagcg
     4441 gttgtggatc atgactcatg atcgtctcct ccgtcgtgat ggtcgttttt ggtgttgcga
     4501 cgaaccagca cggttaagcc cgccagcaca gccagtggta gcatcatgcc tttatacagg
     4561 gtgtgttgaa tattttcgga acgcgcaccg gtagaaagat cgtccagttt cggcaggtcg
     4621 agattttcat aaggcacacc cgtcagtacc agaacctgag taccgccgcc ctctttctcg
     4681 ccgtacagat gcggataata tttcggcacc gtatgcaggt aagtgtcgcc agatttcagc
     4741 gtctgacgcg gatagtggta ttcgctgcca ggcttcagcg ccagacgttt tttcgcctcc
     4801 gccatcagct cttcacgcgt accaaaaatt accgcgcccg ccgggcacac ttctacgcag
     4861 ccaggcaaac cgcctttatc gagacgttcc acacctttct ggttgcacaa ctcgcactta
     4921 tgcagcgcac caaacgggtt gttgtagtcg tacttcggca cgttgtatgg gcaggcgacc
     4981 atgcagtaac ggcaaccggt gcacacatct ttgtcgtaat ggacaatgcc ggttttcgga
     5041 tcttttttca gcgcagagac cgggcacaca gagacacagt tcggatcgac gcagtgcata
     5101 cactgtttct taatgtacgc gtagccgttc tcctcctggt ctttgttgac ccctgtgccg
     5161 ctggtccaca cctgaatgat gttattggta tacggcgaca gtttgtcgtt gttcgaccag
     5221 gtctgttccc cttgcgggtt acgttcaggg aagttgatat cctgacactt ggtgacgcaa
     5281 gcctggcagc ctacgcacaa ggtcgagtcg tacaacatcc ccagcgatcc cggaattggc
     5341 gggcggtttt cagcagccgc atgactgaca gacggcagcg cgcccgtcag caatgccccg
     5401 caggaggctg ctttaataaa attacgtctg ttcacggtta ttctccccgt gagtcagcgt
     5461 tatctttctt ttgctgacga cccagttcac gcaccgccat cacgctgaca ccggcaacca
     5521 gcccaaccac accgccgagc aaaccaatag cgcctgcaga gacgttgccg ccctctttag
     5581 cgttaacatc cggtttctgt gaacgcggag tctgattttc gacgttggca agctgatgga
     5641 tgcctttatg gaagccgata ccttcttcgt tacagccata gcatgggtga ccaatcgcta
     5701 ccggccacac gccgccaaca tcgcagaatt gcagcgttga gcagttgccg taagtttctg
     5761 gccctttaca gccgaggtgg tacaggcacc agccttcacg gtggccttca tcaccgaact
     5821 ctttggcaaa acgaccagca tcgaagtgcg ggcgacgttc gcagtgttcg tgaatcagac
     5881 ggccataggc gaaggtcgga cgatttttgt catccagttt cggcggtttg ccgtaagtga
     5941 tgatgtgcgc aacggtcgcg aggaagttgt gcgggttcgg cgggcagccc ggaatattga
     6001 taacggtttt gcctggcaga acttcttgca ggctgactgc gccagttggg ttaactccag
     6061 ctgcggcaac accgccccac gcagagcagg aaccgatagc gataatcgct gctgcgcctt
     6121 ctgccgcttt gcggatgtga tccacaatcg gctcaccagc aaccatgcaa taaataccgt
     6181 tatcttttaa tgggatggaa ccatccacaa ccaacacata ctgccctttg tacttctcaa
     6241 gtgcgttatg tttgttctct tcgacctgat gaccgaaggc ggcggaaagc acttcgtgat
     6301 actccagaga gatagtctcc agcacgaggt tttctaccgt tggatgcgtt gcacgaagca
     6361 gagattccgt acaaccggtg cactcctgcg cgccaatcca gataactggc ggacgctgcg
     6421 ggttagtaac cgattcggcc atctctgcag cggctttgct acttaacccc atggtggcgg
     6481 ctaatgctgc acaaagcttc atgaaatcac gacggttaat gccgtgagaa tggatgaggg
     6541 tgttatctcc agtcatttat agttattccg ttgcgaagac ctggcatata ttttgcctca
     6601 atcgcaaaat caataatgcg atcgatgcgc catttaccac acatttatta tggttatcga
     6661 tatcatgata ctgcggcggg gcgctaaaac gaagggaaga agcattagtg taattaatta
     6721 aagcaagata atacgtatgt ttgatcaatt ttcgaggcga taaccggcca taaaaaagcg
     6781 caacgtagaa caggaattat tctcacgaaa gaaatccatt accatctctt tatccagtcc
     6841 atagcggcgc gtcagaatac ccgcttccca ggcgctaagc tggcgatctc cggtcttttc
     6901 gtacatccgg tgtgagtagc ctaatacaaa accgcgttta taatcggcac agaattttgt
     6961 cacattaacc gcactgtcgg catgcgttgc ttttaatccc gccattaagc ctttaccaaa
     7021 atggttattc atcgttcacc tcattcgtta tatatcgcca tatatagcga tattttaggc
     7081 aaagaacgac ttttgcgcac gctatttttt catgcttgtt taagacgtaa tccagtaaga
     7141 gataaaccta tcaggagaga tatttatcga accatttcag tgtcctttgc caggcaagat
     7201 cggcggcaga tttgtcataa cggggcgtgg aatcattatg gaatccgtga ttaacccccg
     7261 gatagatata cgcctcataa accttattat tggctttcaa cgccgcctcg taagcaggcc
     7321 agccctcgtt gattcgggtg tccagttccg cgaagtggag tagtaaaggc gcttcaatct
     7381 tcgccacatc ggcagtgggt gcctgacgac cataaaacgg caccgcgcag gccagttccg
     7441 gatacgcgac agccgccgcg ttcgatacgc caccgccata gcaaaatccg gtaataccca
     7501 ctttgcctgc cgcttgcgga tagcgttgca taaactcaat tgcggcaaag aaatcattca
     7561 tcagtttggt tggatcaacc tgctgttgca gctcacgacc tttatcatca tttcccggat
     7621 aacctccaac ggaacttaag ccgtcaggtg ccagggcgat ataccccgcc ttcgccactc
     7681 gccgtgccac atcttcgata tacggattca gtccacgatt ctcatgcacc actaccacgg
     7741 ctggcgtttt gccgctcatt tttgcgggtt tcaccagata accccgtacc tcgccgtgac
     7801 catttggcga aggatacgtg atgtactcag caacaatctc cgggtcggta aactctacct
     7861 gagtcgccag cgcataattt ggcttgagca aatcaaacaa cgctaatgcc gtcatcccgc
     7921 ccaccgcata cttcgccgca aggttgagga actcacgttt cgagattttc ccgtgagcgt
     7981 aatagtcgta gtaatccagc aactcttgtg ggaaatcttt ggcggttaaa cgcggcatcg
     8041 ttgcactcct caattggtgt ttttttaagc aaagcataag cgcgtgtttt tgcccagttt
     8101 ttcgtcactc tgtgagccag actacgggat acgcgctggc gaatcgctaa actagaaaca
     8161 ttgtttcgaa attgaacggt ggaaaggaga ggtcatggtc tggttagcga atcccgaacg
     8221 ttacgggcag atgcaatacc gctattgcgg aaaaagcggt ttacgcctgc ccgcgttatc
     8281 gctcggttta tggcacaatt tcggtcacgt taacgcgctg gaatcacagc gtgcgatcct
     8341 gcgtaaagcg tttgatttgg gcattacgca ctttgattta gccaacaatt acgggccacc
     8401 tccaggaagc gcagaagaga actttggtcg cctgctgcgc gaggattttg ccgcttatcg
     8461 cgatgaactg attatctcta ccaaagccgg atacgatatg tggcccggcc cgtacggctc
     8521 tggcggctca cgtaaatacc tgctcgccag cctcgaccaa agcctgaagc gtatggggct
     8581 tgagtatgtc gatatctttt actctcatcg cgtcgatgaa aatacgccga tggaagaaac
     8641 cgcctctgcg ctggctcatg cggtacaaag cggtaaggcg ctgtatgtcg ggatctcctc
     8701 ttactcgcca gagcggacgc aaaaaatggt cgagttgctg cacgagtgga aaattccgct
     8761 gttaattcat caaccttcgt acaatttact aaaccgctgg gtggataaaa gcggcctgct
     8821 ggataccctg caaaataacg gcgtgggctg tattgccttt actcctctgg ctcagggatt
     8881 gctgaccgga aaatatctca acggcattcc gcaagattca cggatgcatc gtgaagggaa
     8941 taaagttcgt ggtctgacgc cgaaaatgct taccgaagcc aacctcaaca gcctgcgctt
     9001 attgaatgaa atggcacagc agcgtggaca atcaatggcg caaatggcgt taagctggtt
     9061 gctgaaagat gatcgcgtga cgtcggtatt gattggtgcc agccgcgcgg agcaactaga
     9121 ggagaacgtg caggcgctga ataatctgac atttagcacc aaggagctgg cgcagattga
     9181 tcagcatatc gccgatggcg agctgaatct gtggcaggcg tcgtccgata aatgacctgt
     9241 taataacggg cgcgcgaacc gcgcccgaat cagatcagtg attatgacga gtcagtcggt
     9301 caagatagcc catcacaaat gcagaaagca caaacgtcag atggataatg acgtaccaca
     9361 tcagtttgtt atccgggaca tttttcgcat ccataaagac gcgcagtagg tgaatggaag
     9421 aaattgccac aatcgacgct gctactttgt ttttcagcga cgttgcgtcc attttcccca
     9481 gccagttcag cttctctttg ttctcggaga tatccagctg tgagacgaaa ttctcataac
     9541 cggaaaacat caccatcacc agcaaaccgc caaccagcgt catatccacc agcgacagca
     9601 acacgaggat caaatctgat tccgccatcg agaagatatt cggcagtacg tgaataatct
     9661 cctggaagaa cttcagcgcc agggcaacta acgccagcga aaggccaaag tacacggggg
     9721 caagcagcca gcgagaagca tacattgcat tttcaagaaa acgttccata cattcctgtc
     9781 gtgtagttaa aacgggcaac agtatatcgc aattgagtaa acagcacgca acagcaaatc
     9841 aacatatacg ttaaaccttt gtcgcataat tctgaggttt agggatcttc ctggttccct
     9901 tatcaacgca tcgagagcgt ctacccttaa aggacgttga acctgaaggg agaaaaacga
     9961 tgtctcattt aaaagacccg accacgcagt attacactgg tgaatatccc aaacagaaac
    10021 aaccgacgcc aggcatccag gcgaagatga caccggtacc ggattgcggc gagaaaacct
    10081 atgttggtag cggtcgcctg aaagatcgta aagcactggt gacagggggc gattccggaa
    10141 taggtcgcgc tgccgccatc gcttacgcgc gtgaaggggc tgacgtggcg atcagttatc
    10201 ttcccgtgga agaagaagac gctcaggatg tgaaaaagat cattgaagaa tgcggacgca
    10261 aagccgttct gctgccaggc gatttaagcg atgagaaatt cgcccgttcg ctggttcacg
    10321 aagcgcacaa ggcgttaggc gggctggata ttatggcgct ggtcgccggg aaacaggttg
    10381 ccattccgga tattgcagac ctcaccagcg aacagtttca aaagaccttt gccattaacg
    10441 ttttcgcgct gttctggcta acccaggaag cgatccccct gctaccgaaa ggtgcaagta
    10501 tcatcaccac ttcgtcaatc caggcatacc agccaagtcc gcatttactg gactatgcgg
    10561 ctacgaaggc ggcgattctg aactacagcc gtggcctggc aaaacaggtc gcggagaaag
    10621 gtattcgggt gaatattgtc gcgccaggcc ctatctggac ggcactgcaa atttccggcg
    10681 gacaaacgca ggataagatc ccgcagtttg gtcagaaaac gccgatgaag cgtgcggggc
    10741 aaccggcgga actggcccct gtatatgttt atctggcaag tcaggagtcg agctacgtca
    10801 ccgcagaagt gcacggtgtg tgcggcggcg agcatttagg ttaaaaaaat gcccggttgt
    10861 gaaaagcaac cgggcatcat tgtgaattca ctcttacctg atgtggcgaa aacgccttat
    10921 ccgcctacaa acgcatgaag attcaacatg ttgcaataga ttttataggc ctgataagcg
    10981 tagcgcatca ggcattgagc acctaatgcc ggatgcggcg tgaacgcctt atccggccta
    11041 caaacgcacg aagattcaac atgttgcaat agatattgta ggcctgatga gcgtagcgca
    11101 tcaggcaatt ctactttact tcgctttggc ggtttcttcg ccgaccagac ctatcttcag
    11161 gtaacccgcc tgatgcagcg tatccattac cttcatcaac gtctcgtaat cgacggtttt
    11221 atccgctcgg aagaagatgg tggtgtcttt cttgccttcg gttaacgcat tcaacgccgt
    11281 aatcattgtt tcatcggtga ccggatcgtt accgataaac atcgagttgt ctgccttcac
    11341 cgacagataa accggttttt ccgggcgcgg ctgcggcgtg ctggtagaag caggcaagtt
    11401 caccttcaca tctaccgtcg ctaacggtgc cgccaccata aagataatca gcagaaccaa
    11461 catcacgtcg ataaacggcg tcacgttgat atcatgcatt tcgccgttat cgtcgaggtt
    11521 ttcgttaaga tgcattgcca tcggatatta tcctgcgcgt aatttttgtg cgacacgaac
    11581 cggatgcgca gcggcgctgg cttccagatc caggtcacgg ctttgcagca acaatacctg
    11641 cgctgcaaca tcacccagca tcgctttaaa gccgccaatc tggcgtgcaa atacgttata
    11701 gataacgacc gcaggaatcg ctgccacgag gccgattgcc gttgctaaca gagcttctgc
    11761 gatacccggc gcaacgactg ccaggttagt ggtctgcgtt tgcgcgatac caataaagct
    11821 gttcatgatg ccccagaccg taccaaacag accaacgaac ggagaaatcg cgccgatggt
    11881 tgccagatag ccgttaccgc ggcccatttg acgacccact gcggcgaccc gacgctccag
    11941 acggaagctg gtacgttctt taataccttc gttatcgtcg ctgccttctg acagttccag
    12001 ctcattctgc gcttcattga gcaaatgcag gcttaagctt ttgctaccaa aatcagcggc
    12061 gatatcgttg gcctggttta aggaacgcgc ttcagccagc agttgctgct cgcgcttaag
    12121 gcgacgcttc tgattgaaga actctacgct cttactgaag aagattgccc aagtgactac
    12181 ggaggccaaa ataagcccaa tcatcacgca cttaacgaca atatcggcgt gctgatacat
    12241 accccagacg gaaaggtccg tctgcattaa attattaccc actgtgtatc tccaggacgc
    12301 aagtcacaaa atctgcgcat aataatatca aaatgacgtc gaattgatag tcgttctcat
    12361 tactatttgc atactgccgt acctttgctt tcttttcctt gcgtttacgc agtaaaaaag
    12421 tcaccagcac gccatttgcg aaaattttct gctttatgcc aattcttcag gatgcgcccg
    12481 cgaatattca tgctagttta gacatccaga cgtataaaaa caggaatccc gacatggcgg
    12541 acaaaaagct tgatactcaa ctggtgaatg caggacgcag caaaaaatac actctcggcg
    12601 cggtaaatag cgtgattcag cgcgcttctt cgctggtctt tgacagtgtg gaagccaaaa
    12661 agcacgcgac gcgcaatcgc gccaatggcg agttgttcta tggacggcgc ggaacgttaa
    12721 cccatttctc cttacaacaa gcgatgtgtg aactggaagg tggcgcaggc tgcgtgctat
    12781 ttccctgcgg ggcggcagcg gttgctaatt ccattcttgc ttttgtcgaa cagggcgatc
    12841 atgtgttgat gaccaacacc gcctatgaac cgagtcagga tttctgtagc aaaatcctca
    12901 gcaaactggg cgtaacgaca tcgtggtttg atccgctgat tggtgccgat atcgttaagc
    12961 atttgcagcc aaacactaaa atcgtgtttc tggaatcgcc aggctccatc accatggaag
    13021 tccacgacgt tccggcgatt gttgccgccg tgcgcagtgt ggtcccggat gccatcatta
    13081 tgatcgacaa cacctgggca gccggtgtgc tgtttaaggc gctggatttt ggcatcgatg
    13141 tttccattca ggccgctacc aaatatctgg ttgggcattc agatgcgatg attggcactg
    13201 ccgtgtgcaa tgcccgttgc tgggagcagc tgcgggagaa tgcctatctg atgggccaga
    13261 tggtcgatgc cgataccgcc tatataacca gccgtggcct gcgcacatta ggtgtgcgtt
    13321 tgcgtcaaca tcatgaaagc agtctgaaag tggctgaatg gctggcagaa catccgcaag
    13381 ttgcgcgagt taaccaccct gctctgcctg gcagtaaagg ccacgaattc tggaaacgag
    13441 actttacagg cagcagcggg ctattttcct ttgtgcttaa gaaaaaactc agtaatgaag
    13501 agctggcgaa ctatctggat aacttcagtt tattcagcat ggcctactcg tggggcgggt
    13561 atgaatcgtt gatcctggca aatcaaccag aacatatcgc cgccattcgc ccacaaggcg
    13621 agatcgattt tagcgggacc ttgattcgcc tgcatattgg tctggaagat gtcgacgatc
    13681 tgattgccga tctggacgcc ggttttgcgc ggattgtata acattgccac ttttggacaa
    13741 ttttgcagac attttattgt gaaaagtctt aaattgttgc gtccgggatc aaggcgtccc
    13801 ggacgattca ggagtacaat aggcaaataa aggcttaaac gctgttccac aggaaagtcc
    13861 atggctgtta ttcaagatat catcgctgcg ctctggcaac acgactttgc cgcgctggcg
    13921 gatcctcata ttgttagcgt tgtttacttt gtcatgtttg ccacgctgtt tttagaaaac
    13981 ggcctgctgc ccgcctcatt tttgccaggc gacagcttgt tgatactggc aggcgcattg
    14041 attgcccagg gggttatgga ttttctgcct acgattgcga ttctgaccgc cgcagcaagt
    14101 ctgggctgct ggctaagtta tattcagggg cgctggttag ggaataccaa aacggtgaaa
    14161 ggctggctgg cacagcttcc tgctaaatat caccagcgcg ccacctgcat gtttgaccgc
    14221 cacggtctgc tggcgctgct ggctggacgt tttcttgcat ttgtccgtac gctgctgcca
    14281 accatggcgg gaatttccgg tctgccaaac cgccgtttcc agtttttcaa ctggttaagc
    14341 ggattgctgt gggtcagcgt ggtaaccagt ttcggctatg ccttaagtat gattccgttc
    14401 gttaaacgcc atgaagatca ggtaatgacg ttcctgatga tcctgccaat tgccttgtta
    14461 accgctggct tgttaggcac gctgtttgtg gtgattaaaa aaaaatactg taacgcctga
    14521 cgattttccc tgttcccggt tgctgtaccg ggaacgtatt taattcccct gcatcgcccg
    14581 cattcttgcc gcatcttccc ccggcgtcac accgaagtaa cgtttaaact cacggctaaa
    14641 ttgcgatgcg ctttcatagc cgacgcgcat cgctgctgcg ctggccttca tgccgtcatg
    14701 gatgatcatc atccgcgcct tatgcagacg gtaattcttc aaatactgca acggcgaggt
    14761 actggtgaca gacttaaaat tatggtggaa cgccgatacg ctcatgttgg cttctgccgc
    14821 cagttgctcg acgctcaggt tttcggtgta tttattctca atccgtttca gcacgcggct
    14881 aatcagactg aagtgagtct ggcgactgac cagcgccagt aacgcgccgc cgcaaggtcc
    14941 ggtcagcacg tagtacagaa tttcgcggat gatctgtttg ccgagaatac gcgcatccag
    15001 tggtcgctcc atcacgtcga gtaaccgctc cgccgcgcat aaaatctctt ctgataacgt
    15061 ggcggagtta atcccgctgg ctgccatcga cggctggaaa tgctcatctt cgccaatgtc
    15121 catcaacagt tcctgtaact gcaaaatatc gacattgaga cgcaaccctg ccagcggcac
    15181 ctctgacgtg gcataggttt cgcactcaaa cggcaacggc accgtcagca gcaggtattc
    15241 attggcatca taacgaaaca cgcgttcatt gatataaccg attttatgcc cggaaaagag
    15301 aattatgatg ccaggctcgt acatcaccgg tgtacgtgcg aaaggcgtct cgccatacaa
    15361 caaacgcaca tcgggcaaca gttctgacaa actattttct ttaattttca gtttattaac
    15421 tttatccgcc agcaagcggc aaatctcttc acgtttcata tcgcgtaatt tcttaggaat
    15481 aatgcggcaa tttgattgtg cgcaattttg tagcatttct ccagcactct ggaggaatag
    15541 gcaagacatt ggcagaaatg agcattgaga gccagggcgc tggcgatcac aatgaaaaac
    15601 atcaggcaga tcgttctctg ccctcatatt ggcccagcaa agggagcaag taatgaacaa
    15661 ctttaatctg cacaccccaa cccgcattct gtttggtaaa ggcgcaatcg ctggtttacg
    15721 cgaacaaatt cctcacgatg ctcgcgtatt gattacctac ggtggcggca gcgtgaaaaa
    15781 aaccggcgtt ctcgatcaag ttctggatgc cctgaaaggc atggacgtgc tggaatttgg
    15841 cggtattgag ccaaacccgg cttatgaaac gctgatgaac gccgtgaaac tggttcgcga
    15901 acagaaagtg actttcctgc tggcggttgg cggcggttct gtactggacg gcaccaaatt
    15961 tatcgccgca gcggctaact atccggaaaa tatcgatccg tggcacattc tgcaaacggg
    16021 cggtaaagag attaaaagcg ccatcccgat gggctgtgtg ctgacgctgc cagcaaccgg
    16081 ttcagaatcc aacgcaggcg cggtgatctc ccgtaaaacc acaggcgaca agcaggcgtt
    16141 ccattctgcc catgttcagc cggtatttgc cgtgctcgat ccggtttata cctacaccct
    16201 gccgccgcgt caggtggcta acggcgtagt ggacgccttt gtacacaccg tggaacagta
    16261 tgttaccaaa ccggttgatg ccaaaattca ggaccgtttc gcagaaggca ttttgctgac
    16321 gctaatcgaa gatggtccga aagccctgaa agagccagaa aactacgatg tgcgcgccaa
    16381 cgtcatgtgg gcggcgactc aggcgctgaa cggtttgatt ggcgctggcg taccgcagga
    16441 ctgggcaacg catatgctgg gccacgaact gactgcgatg cacggtctgg atcacgcaca
    16501 aacactggct atcgtcctgc ctgcactgtg gaatgaaaaa cgcgagacca agcgcgctaa
    16561 gctgctgcaa tatgctgaac gcgtctggaa catcactgaa ggttccgacg atgagcgtat
    16621 tgacgccgcg attgccgcaa cccgcaattt ctttgagcaa ttaggcgtgc cgacccacct
    16681 ctccgactac ggtctggacg gcagctccat cccggctttg ctgaaaaaac tggaagagca
    16741 cggcatgacc caactgggcg aaaatcatga cattacgctg gatgtcagcc gccgtatata
    16801 cgaagccgcc cgctaagctt tttacgcctc aaactttcgt tttcgggcat ttcgtccaga
    16861 cttaagttca caacacctca ccggagcctg ctccggtgag ttcatataaa ggaggaacgt
    16921 atggctaatc caaccgttat taagctacag gatggcaatg tcatgcccca gttgggactg
    16981 ggcgtctggc aagcaagtaa tgaggaagta atcaccgcca ttcaaaaagc gttagaagtg
    17041 ggttatcgct cgattgatac cgccgcggcc tacaagaacg aagaaggtgt cggcaaagcc
    17101 ctgaaaaatg cctcagtcaa cagagaagaa ctgttcatca ccactaagct gtggaacgac
    17161 gaccacaagc gcccccgcga agccctgctc gacagcctga aaaaactcca gcttgattat
    17221 atcgacctct acttaatgca ctggcccgtt cccgctatcg accattatgt cgaagcatgg
    17281 aaaggcatga tcgaattgca aaaagaggga ttaatcaaaa gcatcggcgt gtgcaacttc
    17341 cagatccatc acctgcaacg cctgattgat gaaactggcg tgacgcctgt gataaaccag
    17401 atcgaacttc atccgctgat gcaacaacgc cagctacacg cctggaacgc gacacacaaa
    17461 atccagaccg aatcctggag cccattagcg caaggaggga aaggcgtttt cgatcagaaa
    17521 gtcattcgcg atctggcaga taaatacggc aaaaccccgg cgcagattgt tatccgctgg
    17581 catctggata gcggcctggt ggtgatcccg aaatcggtca caccttcacg tattgccgaa
    17641 aactttgatg tctgggattt ccgtctcgac aaagacgaac tcggcgaaat tgcaaaactc
    17701 gatcagggca agcgtctcgg tcccgatcct gaccagttcg gcggctaaca tgcaaattct
    17761 cccggtggcg gtaatgttcc gctaccggac ttttcagaaa tcatttattc ccctcgcgtc
    17821 ccgcccgttg ttactcttcc ttgttcagga atgccaaata taaggacatc atcatgcaga
    17881 gccggaagct cttaaaagaa caactcatct atatccggga taaacgcaac ggagaggtga
    17941 aaaacagatg aaaataatac ttctgttttt agcagccctg gcaagtttta ccgtacacgc
    18001 acagcccccc tcactgaccg tagaacaaac agtccggcat atttatcaga actataaatc
    18061 agatgccact gccccttatt ttggtgaaac cggagagcgg gcgataactt ctgcgcgtat
    18121 tcaacaggcg cttaccctga acgacaatct tacgctgccg ggcaatattg gctggctgga
    18181 ttatgatccg gtttgtgatt gtcaggattt tggcgatctg gtgctagaaa gcgttgcgat
    18241 aacccaaact gacgccgatc atgccgatgc cgttgtgcgc tttcgtatct ttaaagatga
    18301 taaagaaaag accacgcaga cactgaaaat ggtggcggaa aatggtcgtt gggtcattga
    18361 cgatattgtc agcaatcatg gcagcgtctt acaagcagtt aatagcgaga atgaaaaaac
    18421 gctggccgct ttagcttcgt tgcaaaaaga acagccggaa gcctttgttg ccgaactctt
    18481 tgaacatatt gctgattata gctggccgtg gacgtgggtg gtttccgact cttaccgcca
    18541 ggcggttaat gccttctata aaaccacctt caagacggcc aataatcccg atgaagatat
    18601 gcaaatagaa cggcaattta tttacgacaa tccgatctgt tttggcgaag agtcgctatt
    18661 ttcacgcgtt gatgaaattc gagtcctgga gaaaaccgcc gattccgccc gcattcatgt
    18721 tcgttttacg ctgaccaatg gcaacaacga agagcaagaa ctggttttac agcggcgcga
    18781 aggcaagtgg gaaatcgctg attttatccg cccgaacagc ggcagcctac ttaagcagat
    18841 tgaggcaaaa accgccgcca gattaaagca atgagctgaa ttaaataaca attagccgga
    18901 acaataaata aaagggaaca ctatatgaaa acgattttca ccgtgggagc tgttgttctg
    18961 gcaacctgct tgctcagtgg ctgcgtcaat gagcaaaagg tcaatcagct ggcgagcaat
    19021 gtgcaaacat taaatgccaa aatcgcccgg cttgagcagg atatgaaagc actacgccca
    19081 caaatctatg ctgccaaatc cgaagctaac agagccaata cgcgtcttga tgctcaggac
    19141 tattttgatt gcctgcgctg cttgcgtatg tacgcagaat gataaaaaaa tccccggcag
    19201 catgtcagtt gccggggatt ttttttaacg tccaaccgcc gctttagggc gtttcttcgc
    19261 accagcattc accggacgag attgcgtaga cgacgctttt tttgccgtag caggcgtctg
    19321 acgctgggtc gccatcggcg tatgtttcgt caacgccgga cgggtattgc ggttctggcg
    19381 acgagcttca cgcatctctt caatggttgg cgcaggcact aagcaatcgc gacggctgcc
    19441 aatcagatgc tttttgccca tcgcttccag cgcctggcgg attaacggcc agtttgccgg
    19501 atcgtggtaa cgcaacaacg ctttatgcaa acgacgctgt ttgtcgccct tcggtacgaa
    19561 gacgtcttcg ctcttataac caatcttcgc cagcgggttt ttcccggtgt aatacatggt
    19621 ggttgagttc gccagcggcg atgggtagaa gttctgtacc tggtcgagac ggaaacgatg
    19681 ctttttcagc cacagcgcca gattcaccat atcttcatca cgcgtaccgg ggtgcgcgga
    19741 gatgaaatag gggatcagat actgctcttt acctgcctgt tttgagtaag tatcgaacag
    19801 ctctttaaag cggtcatagc tgcccatgcc cggcttcatc atcttcgata acggcccttc
    19861 ttcggtatgt tccggggcaa tcttcagata accgccgacg tgatgggtcg ccaactcttt
    19921 gatatagcgc ggatcttcca cggcgatgtc ataacgtacg cctgaggcga tgaggatttt
    19981 tttaatgcct ttcagatcac gcgcacggcg atagaggttg atcgtcggtt cgtggttagt
    20041 gtccatgtgc ggacaaatat ccggataaac gcacgacaaa cggcgacaag tttgttcagc
    20101 gcgtggcgat ttgcagcgca acatatacat gttggcagtt ggcccaccga gatcggaaat
    20161 cacgcccgta aaacctggaa cggtgtcgcg gatcgcttcg atctcattaa tgatcgaatc
    20221 ttccgaacgg ctctgaataa tgcgcccttc gtgctcggta atagaacaga aagaacagcc
    20281 gccaaagcag ccgcgcataa tgttgaccga aaaacggatc atttcgtaag ccggaatacg
    20341 ggcattgcca taggccggat gtggcacgcg cttgtacggc agcgcaaaaa cgctgtccat
    20401 ctcttcggta gaaagcggga tagcaggcgg gttgatccac acatagcggt caccgtgttt
    20461 ttgcatcaat gcgcgggcgc agcctgggtt ggtttcgtgg tgcagaatgc gcgaagcatg
    20521 ggcgtacagc actttatcgc ccttcacttt ctcgaaagaa ggcagcaaca cgtaggtttt
    20581 ttcccacggt ttcgggcgcg gtggctgcac ggttacggct ttggcttcct gctttttcgg
    20641 tgccaccggt ttgttatccg cgcacggcaa atcttcacca tacggatgcg ggattgggtc
    20701 gatttttcca ggggtatcaa gacgggtgga atccacgccg ctccagccag gcagcgcctc
    20761 tttcacgata atcgcggtat tacgcacatc gcggatttca ctaatcggct cgcccatcgc
    20821 cagacggtgc gccacctcca ccagcggacg ctcaccgtta ccaaacatca gcatgtcggc
    20881 tttcgaatcc accagcacgg aacggcgcac ggtatcggac cagtaatcat aatgtgcggt
    20941 acggcgcaga ctagcctcaa taccgccgag gatcaccggt acatctttcc acgcctcttt
    21001 acaacgctgg gtataaacca gtgtggcgcg atccgggcgc ttacccgcga cgttatccgg
    21061 cgtgtaggca tcgtcatgac gtaaacggcg atcggcggta taacggttga tcatcgaatc
    21121 catgttgcca gcagtaacac cgaaaaacag attcggttta cccagacgca tgaaatcgtc
    21181 tttgctgctc cagtctggct gggcgatgat cccgacgcga aagccctgtg cttccagcat
    21241 acgaccgcaa atcgccatcc cgaagcttgg gtgatcgaca tacgcgtcgc cagtaaccaa
    21301 aatgatgtcg cagctatccc agccaagttg atccatctct tcacgagaca tcggcaaaaa
    21361 cggtgccggt ccaaaacagg cggcccagta ctgcggccag gagaacaggt cgcgatccgg
    21421 ttggatcagg gagatagagc tcattttgct tccagaaatg ataaaaaaat aatcaaaggc
    21481 cggggattat aagccggaac gaaagagaaa tcgaaaggta ttccatactc gccctcctcg
    21541 ggcgagtatg aagattacgg taccggattg accaacagtt gcccaatcga gccacggtcc
    21601 gccatttcca gcgtctgact gttgaagtag aacgggaagt gcgcccagga aggctgaccg
    21661 aaataaacaa gcagctccac ttgtccgtca acccaaacgg tatctttcca gcctctgtct
    21721 tccgggaacg gcatcgcgcc attcacgtta cggatctgga acatcacgcc ttcaatatgg
    21781 aacgcttgcg gctcgtccgc gcgtaccgtc cagcgttccc acgttccttg ctgcgcggtg
    21841 acatcaatac ggttgacgtc ccacagctgt ccattaatac ccgggtcatc acccagactg
    21901 atatcgcgac tgcgaattgg cgaaccagcc atgatttcag ttggcagcaa gcgcatcgga
    21961 agactgtctg tgaccagcgg cagaaggccg gttgggcgca gcgttagcac cagggtagaa
    22021 accagaatac tggatggctc aaagaagccg cgaatacgat caacaatgct cgccgcttcg
    22081 ccacaggtga tcgacacttc atcgccgttg ctcatatcca ccagaatctc gcggcgctcg
    22141 cccggtgcca gcgaaagttg cttcaccgat acaggagcag gcaggaatcc ctgatcgcca
    22201 gaaatcacat gtaacgggcg accatcgctc atctgtagtt gatagcgacg agagttcgac
    22261 gcgttcagca gtcgcaagcg cacccagcca cgcgagactt caacgtacgg gctttgtaca
    22321 ccgttaacca gcagcgtatc accaacaaag ccgccgcttc ccggttcgtt gtattctggc
    22381 gtaccaaagt tatccagccg tttatcctgg ataatgaccg gaaaatcatc cacaccataa
    22441 tggttgggga taggcagcga cttgctgact tcatcttcca ccagccacat tccggcaagg
    22501 ccgttataga cctgctgagc cgtgcggttg ggagtattgg cgtgatacca cagagtagct
    22561 gcgttctggc gaatgggcag tacgggtgcc cagtcagcgt ttggcgacat catccgtgcc
    22621 ggaccgccca tcagcgggcc tggtacctgt agcccggcca ccgtcattga gacattttct
    22681 gtcaggcggt tgctgtaaat aagcttaaca tcgtcgccct tccagacgcg gatagtcggc
    22741 cccaggtaac gaccattgat tccccagacc gacgcgcgtg tccctggcgt aaatgaccag
    22801 tgcgcacgtt gtacagtcat aaacagcggt tgcccacggc gagattcaag tagcggcgga
    22861 acgggtagcg gttgctgttg cccggctgcg ctggccttca ggggaacagc gcctgcacaa
    22921 agtgcaatcc ccgatgcctg aatgaactga cgccgactga gtgacatatt tgctccatgt
    22981 aaaactggct aaagtaatac cgtgcaggaa agtgttcccc gcaaaaatac agattgccga
    23041 cttaaacttt tccggcggct tcgcgttctg cgacttcttt atcgagctcg gcgatttttt
    23101 gttccattat cgaacgacaa tgggcagcca gctcacgaac ctgatctttg ccatactgac
    23161 tgacgtcaat tggcggcagc atttcgacaa tcaccagacc gttgtgcagt cgattaagat
    23221 taatcttatt cgaagttgta gagacgcaca cgggaataat cgggacgccc gccgcaattg
    23281 ccgcgtgaaa tgctccagtc ttgaacggta gcaggccgcg accacggctg cgggttcctt
    23341 ccgggaacat ccagatggaa atacggcgtt ttttgaaatg attcacgact tccgcaatgg
    23401 tgccgtgagc tttagtgcga ttgtttctgt cgatcaataa gttgccggtt aaccagtaca
    23461 actgcccgaa gaaggggatc cacagcaagc tctttttacc taccgtcacc gtcggcggtt
    23521 gcacaatgtt cgatgctgtc accatgtcat agttgttctg gtggttagcg atatagatag
    23581 cattgccgta gctttcagca tctgcaggtt tgcggcactc aactttcagg ccgaacagcg
    23641 gcgcaagacg gccaaacata tgcccaaagg tggccacatg tttcgggtta cgcgggctga
    23701 aaaggcagta aatggagccg aatacacaga ctaagatgct gtaaatcacg gtaataataa
    23761 gacgaaagat atatagcata acaccctctg aaggtctgag agactggcat tgtacgtcac
    23821 ctgaaatcag gttagggcat tgttaaaagc cgctctctgg aaaagcgtat tgttaatcgc
    23881 aacgcatgaa taaacaacgg tttcaaggga atttttatcg tttccggggg ttgaatacgc
    23941 tgccggatga cgacttaacg tttcatccgg cgttccttgc aagcgggagg aaacagcgcc
    24001 ctccccggca tattactctt cgctatcacc gctgctggca cggcgaggag agtcgatctc
    24061 aacacgatcg atacgctgca aaccgcgcat caacgtaccg cggcgtccac gttcgccagt
    24121 gactttctgt agctcttccg gacgcagttt aattttgcgt ttcccaacat gaatggtcag
    24181 cgtgctttgc ggcggcagaa cgtacagttg cgccagacca tcctcgccac gcgcggcttc
    24241 tgccgatgga atgttgataa tcttgttgcc tttgcccttc gacagctgcg gcagatcgct
    24301 taccgggaac atcaacatac ggcctgcctg agtgattgcc agcagcatgt cggaagcatc
    24361 ttcaatcacc accggcggca taacatgggc attttccggt aaggttatca aagctttacc
    24421 tgcacggtta cgcgccacca gatcgttaaa ggtgcagacg aaaccgtaac ccgcatcgga
    24481 agccatcagc agtttctgat cgtcgctttc catcagcata tggtcaacgg tcgccccagg
    24541 cggcaacgtt aatttgccgg tgagcggctc gccctgacca cgcgccgacg gcagcgtaat
    24601 cgggtcgatg gcatagctac gaccggtgga atcaacaaac actaccggtt ggttgctctt
    24661 acctttcacc gcagctttga agctatcacc cgctttataa ttcaggcccg gcgcgtcgat
    24721 atcatggcct ttagcgctgc gtacccagcc catctgcgac agcacaatgg tgacaggttc
    24781 agacggcagc atgtcgtgct cgctcatcgc tttcgcttct tcgcgttcct gcaacggcga
    24841 acgacgatcg tcaccgtagg cttgcgcgtc tgcctgcagt tctttcttca gcaggttatt
    24901 cattttacgc tcggaagcca aaatgccctg caactggtcg cgctcttttt cccgctcact
    24961 ctgctcaccg cgaatcttca tctcttccag tttggcaaga tgacgcagtt tcagttcgag
    25021 gatcgcttcc gcctgggttt ccgtaaggcc aaaccgcgac atcagcgccg gtttcggttc
    25081 atcttcgtta cgaatgatct caatcacttc gtcgatgttg agaaacgcca ccagcaaacc
    25141 ttccaggata tgcaggcgct tgaggacttt ctccagacga tagttcagtc ggcggcgcac
    25201 ggtatcgcga cggaacacca gccattcgga gaggatttcc agcaggtttt tcaccgccgg
    25261 acgaccatcc agaccgatca tattgaggtt aatgcgatag ctcttttcca gatcggtggt
    25321 agcgaagagg tggttcatca cctgatccat atccacgcgg ttggaacgcg gcacaatcac
    25381 cagacgggtc gggttctcgt ggtcagattc atcgcgcaga tcgtcaacca tcggcagctt
    25441 tttgttgcgc atttgcgcag caatttgctc cagtacgcgc gcacctgaaa cctgatgcgg
    25501 taatgcgctg ataaccaccg cgccatcttc tttcttccac accgcgcgca tacgcactga
    25561 accacgtccg ttctcgtaga ttttacggat ctcggcgcgc gaagtgataa tttccgcttc
    25621 agtcggataa tccggcccct gcacgatatc cagcagctga tcgagcgtgg ttttcggctg
    25681 gtcgattaat gcgattgccg cctgagctac ttcacgcagg ttatgcggtg gaatatcggt
    25741 cgccatgccg acggcaatac cggtggtgcc gttaagcaaa atgtttggca gacgggcagg
    25801 cagcattttc ggctcctgca aagtgccgtc gaagtttggc acccagtcag ccgtcccctg
    25861 ccccagctcg ctcaatagca gctcggaata tttcgacaac cgggattcgg tgtaacgcat
    25921 tgccgcgaac gatttcggat cgtccggcgc gccccagttc ccctgaccat caaccagcgg
    25981 ataacggtaa gagaacggct gcgccatcag gaccatcgct tcataacagg cgatatcgcc
    26041 gtgcggatgg tatttaccca gtacgtcacc gacggtacgg gccgattttt taaatttggc
    26101 gctggcattc aggcccagtt cagacatcgc atacacaatg cggcgctgaa caggtttaag
    26161 accatcgcca ataaacggca acgcacggtc catgatcacg tacatggagt agtttaagta
    26221 ggcgttttcc gtaaattcat gtagcgcaag gcgctctgcc atatcgctca ttaattctga
    26281 ttcctcaact tattcgccag ccttcaaagg ggcaatattg ccggagatac tacattatct
    26341 gccgcgtcga gtcacaggag atcagcgtga atagcgccgc cggacgtgct ccgacggcga
    26401 taaaggcatc aatgtgcctt gatatacaac tctttgctgt agacttgatc ggcatagagg
    26461 gcagcacaag tttgcgccca tgccacacca ctcggcatgg gggtccgctc cgggcgattc
    26521 gagaagttga ggttatgcga gtccagggaa gcctaaagca tcaaagtagt cgactgtaag
    26581 tatacggttc agcccagttt agctgtgtct ccaccagtgc cccgcgcctc ctgccataag
    26641 tgcggcttgc tcatggatac ccccgagacg gcttacggcg caccggataa taaatttcgc
    26701 gtatacatgg tattccttac cggagaaatt ataagcccaa caacaatacg cctgtggcat
    26761 tgttcgctca aacttatcgc gagtgatttg gctcacactc cggtaaagat tccccatcac
    26821 gccaacggca cataaacatc cgtttccagt cgctgctctg tcaccccttc ggcaagattg
    26881 gtgtagtgaa acagaatcgg tgctttacgc attttctcgc cgcttgcagg cagccagtgg
    26941 cgaataatgc cccatatcgt gtgtgaaata tcgtccagct cgccaacgtg gcgggccacg
    27001 gcataacgtc caccggtaag ttcaccattg ctcacaccat aacgattatc gggaatcggt
    27061 tcgctaacgc tgccgcagat atcaaagcga aacgcttccg gtgcggtggt ggcagggtcg
    27121 tcccaggcga cgccaaaagt ctggctttgg ttaacaggag aaagccccgt ctctttacgc
    27181 cacatgataa atttcgccac actgtagttg agcaactcag ggctacagcg gtgcggcaac
    27241 atcgccacag ggattgatgg gaaatcgata atgtttacat ccagtgtcag gtttgtcatt
    27301 ttgcctccct gcgaaattat tcccgggaac gcgtcccggg agcggtaaca attacggatt
    27361 tactttgcgg atctgtttga cgtcaatttc aacagaattc cagtctttat cgacttcacc
    27421 ctgaatctca accgtatctt tcggcgtcac cgtcacaccg ttccagcgtt tgtggtcgat
    27481 atcaacattg atagtaccgc tggcatcttt aaacacgtag agatcgtcag agatgcgttc
    27541 aacgatattg ccgcgcaggg ttacccaggt gtcgtcacgc agggattttg cgctttctac
    27601 ggtcgttacg ctgccgttcg gcccctggaa tcctccggcc tgactttgcg ttgccgatgg
    27661 gccagaaaaa ccgccctgct ctgctgccat caccggtgcg ctgcacaggg ccattactgc
    27721 gattactgct gcgaattttt tcatgtttat tactcccttt aatgtctgtt tccgagcatt
    27781 taacaagata gtccttaaca acttcttaag ggaaaaaaat aaaatttagt gctgtacaga
    27841 gcgcgttaca acacggttta ctggcagcaa atacggttat cgcagggatg aaaaaatgcg
    27901 aattttactg atagaagatg acatgctgat tggcgacggc atcaaaacgg gccttagtaa
    27961 aatgggtttt agcgtcgact ggtttacaca aggtcgtcag ggaaaagagg cgctttatag
    28021 cgcgccttat gatgcggtga tcctggattt aaccttacca ggcatggatg gtcgcgatat
    28081 tttgcgcgaa tggcgagaaa aaggtcagcg tgagccggta ctgatcctga ccgcgcgcga
    28141 tgcgctggag gaacgtgtag aagggctgcg tctgggagct gacgattatc tgtgtaaacc
    28201 ttttgcgttg atagaagtcg ccgccaggct ggaagctctg atgcgccgaa ccaacggcca
    28261 ggccagcaac gagctgcgcc acggtaacgt catgctcgac cccggcaaac gtatcgccac
    28321 gctggctggc gaacccttaa cactgaaacc aaaagaattt gccctgctgg aattactgat
    28381 gcgtaacgct ggtcgggtac tgccgcgcaa actgattgaa gagaaactgt atacctggga
    28441 cgaagaggtc accagtaatg ccgttgaagt gcatgtgcat catctgcgac gcaaactcgg
    28501 tagtgatttt attcgtaccg tgcatggtat tggctacaca ttaggtgaga aatgaaattt
    28561 acccaacgtc ttagtctgcg cgtcaggctg acgctaatct ttttaattct ggcctcggtg
    28621 acctggctgc tttccagctt tgtcgcctgg aaacaaacaa cggataacgt cgatgaattg
    28681 ttcgacaccc aactgatgct gtttgccaag cggttaagta cgctcgatct caacgaaatc
    28741 aacgcggcgg atcgcatggc acagacgcca aataaattaa aacacggtca tgttgatgac
    28801 gatgcgctga cctttgccat ctttacccac gacggcagaa tggtccttaa cgatggcgat
    28861 aacggagaag atattcctta tagctatcaa cgggaaggtt ttgctgacgg gcaactggtg
    28921 ggcgataaag atcaatggcg ttttgtctgg atgacctcac ctgatggcaa atatcgcatc
    28981 gttgttggtc aggaatggga ataccgtgaa gacatggcgc tggcgattgt tgccgggcaa
    29041 ttgatcccgt ggctggtcgc actgccgatt atgttaatca tcatgatggt actattgggt
    29101 cgtgaactcg cgccgctgaa caaactggcg ctggcgctgc gtatgcgtga ccctgactcg
    29161 gaaaaaccac taaacgcgac tggcgtaccc agcgaagtgc gtccgttggt tgagtcgcta
    29221 aatcaactgt tcgcccgcac acatgcgatg atggttcgtg aacgacgctt tacctccgac
    29281 gcagctcacg aactacgtag cccgttaacg gcgctgaaag tgcaaaccga agttgcgcag
    29341 ctttctgacg atgatccgca agcgcggaaa aaagcgctgc ttcaattaca ttacgggatc
    29401 gatcgcgcta ctcgtctggt tgatcaactg ctcactctat cgcggctgga ctcactggat
    29461 aaccttcagg acgtcgcgga gatcccgctt gaagatctcc tgcaatcgtc ggtgatggat
    29521 atttaccaca cggcgcagca ggcgaaaatt gacgtgcgac tgacactcaa tgcccacggc
    29581 atcaaacgca ccggacaacc gctattgcta agtttgttgg tgcgaaattt gctggataac
    29641 gccgtgcgct acagtccaca gggcagcgtg atagacgtca cgctgaatgc tgataatttc
    29701 atcgtgaggg ataacggccc cggtgtgacg ccagaggctc tggcgcgaat tggcgaacgc
    29761 ttctatcgcc cccccggaca aaccgctacc ggcagtggac ttgggctatc gattgtccag
    29821 cgaatcgcca aattgcatgg catgaatgtt gagtttggga atgcggaaca aggtggattt
    29881 gaggcgaagg taagctggta acttctctgt ctatgagagc cgttaaaacg actctcatag
    29941 attttactaa tagcaaaata taaaccgtcc ccaaaaaagc caccaaccac aaaccagaca
    30001 aataccgagc gagaatacat atacccaaaa ctcgaacatt tcccgcataa agagttttct
    30061 taagataaga ataataagtg gcgtaagaag aaaaaatgct gcaatcattg cttgcaatat
    30121 acgatcttcg cctgaaacgg aaggtatact gcaaatattg tctcccgact caagcatcca
    30181 gtcatactta ttgaaagcaa aaaaagcatc tattaaccaa taag
//
LOCUS       DAPOAV010000052        30040 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.052, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000052 DAPOAV010000000
VERSION     DAPOAV010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 30040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30040
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.052"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(29..1483)
                     /gene="xylB"
                     /locus_tag="RN951_002648"
     CDS             complement(29..1483)
                     /gene="xylB"
                     /locus_tag="RN951_002648"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HDX2527629.1"
                     /translation="MYIGIDLGTSGVKVILLNEQGEVVAAQTEKLTVSRPHPLWSEQD
                     PEQWWQATDRAMKALGDQHSLQDVKALGIAGQMHGATLLDAQQRVLRPAILWNDGRCA
                     QECTLLEARVPQSRVITGNLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRM
                     TGEFASDMSDAAGTMWLDVAKRDWSDVMLQACDLSRDQMPALYEGSEITGALLPEVAK
                     AWGMATVPVVAGGGDNAAGAVGVGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHS
                     FCHALPQRWHLMSVMLSAASCLDWAAKLTGLSNVPALIAAAQQADESAEPVWFLPYLS
                     GERTPHNNPQAKGVFFGLTHQHGPNELARAVLEGVGYALADGMDVVHACGIKPQSVTL
                     IGGGARSEYWRQMLADISGQQLDYRTGGDVGPALGAARLAQIAANPEKSLIELLPQLP
                     LEQSHLPDAQRYAAYQPRRETFRRLYQQLLPLMA"
     gene            complement(1555..2877)
                     /gene="xylA"
                     /locus_tag="RN951_002649"
     CDS             complement(1555..2877)
                     /gene="xylA"
                     /locus_tag="RN951_002649"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HDX2527630.1"
                     /translation="MQAYFDQLDRVRYEGSKSSNPLAFRHYNPDELVLGKRMEEHLRF
                     AACYWHTFCWNGADMFGVGAFNRPWQQPGEALALAKRKADVAFEFFHKLHVPFYCFHD
                     VDVSPEGASLKEYINNFAQMVDVLAGKQEESGVKLLWGTANCFTNPRYGAGAATNPDP
                     EVFSWAATQVVTAMEATHKLGGENYVLWGGREGYETLLNTDLRQEREQLGRFMQMVVE
                     HKHKIGFQGTLLIEPKPQEPTKHQYDYDAATVYGFLKQFGLEKEIKLNIEANHATLAG
                     HSFHHEIATAIALGLFGSVDANRGDAQLGWDTDQFPNSVEENALVMYEILKAGGFTTG
                     GLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKIAARMIEDGELDKRIAQRYSGWNS
                     ELGQQILKGQMSLADLAKYAQEHHLSPVHQSGRQEQLENLVNHYLFDK"
     gene            3243..4235
                     /gene="xylF"
                     /locus_tag="RN951_002650"
     CDS             3243..4235
                     /gene="xylF"
                     /locus_tag="RN951_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose ABC transporter substrate-binding
                     protein"
                     /protein_id="HDX2527631.1"
                     /translation="MKIKNILLTLCTSLLLTNVAAHAKEVKIGMAIDDLRLERWQKDR
                     DIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEA
                     KQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVPQGNYFLMGGSPVDNN
                     AKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVAS
                     NDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAE
                     IAVELGNGQEPKADTTLNNGLKDVPSRLLTPIDVNKNNIKDTVIKDGFHKESEL"
     gene            4313..5854
                     /gene="xylG"
                     /locus_tag="RN951_002651"
     CDS             4313..5854
                     /gene="xylG"
                     /locus_tag="RN951_002651"
                     /EC_number="7.5.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose ABC transporter ATP-binding protein"
                     /protein_id="HDX2527632.1"
                     /translation="MPYLLEMKNITKTFGSVKAIDNVCLRLNAGEIVSLCGENGSGKS
                     TLMKVLCGIYPHGSYEGEIIFAGEEIQASHIRDTERKGIAIIHQELALVKELTVLENI
                     FLGNEITHNGIMDYDLMTLRCQKLLAQVSLSISPDTRVGDLGLGQQQLVEIAKALNKQ
                     VRLLILDEPTASLTEQETSVLLDIIRDLQQHGIACIYISHKLNEVKAISDTICVIRDG
                     QHIGTRDAAGMSEDDIITMMVGRELTALYPNEPHTTGDEILRIEHLTAWHPVNRHIKR
                     VNDVSFSLKRGEILGIAGLVGAGRTETIQCLFGVWPGQWEGKIYIDGKQVDIRNCQQA
                     IAQGIAMVPEDRKRDGIVPVMAVGKNITLAALNKFTGGISQLDDAAEQKCILESIQQL
                     KVKTSSPDLAIGRLSGGNQQKAILARCLLLNPRILILDEPTRGIDIGAKYEIYKLINQ
                     LVQQGIAVIVISSELPEVLGLSDRVLVMHEGKLKANLINHNLTQEQVMEAALRSEHHV
                     EKQSV"
     gene            5832..7013
                     /gene="xylH"
                     /locus_tag="RN951_002652"
     CDS             5832..7013
                     /gene="xylH"
                     /locus_tag="RN951_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose ABC transporter permease XylH"
                     /protein_id="HDX2527633.1"
                     /translation="MSKSNPSEVKLAVPTSGGFSGLKSLNLQVFVMIAAIIAIMLFFT
                     WTTDGAYLSARNVSNLLRQTAITGILAVGMVFVIISAEIDLSVGSMMGLLGGVAAICD
                     VWLGWPLPLTIIVTLVLGLLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGT
                     TVSPTSAAMSQIGQSYLPASTGFIIGALGLMAFVGWQWRGRMRRQALGLQSPASTAVV
                     GRQALTAIIVLGAIWLLNDYRGVPTPVLLLTLLLLGGMFMATRTAFGRRIYAIGGNLE
                     AARLSGINVERTKLAVFAINGLMVAIAGLILSSRLGAGSPSAGNIAELDAIAACVIGG
                     TSLAGGVGSVAGAVMGAFIMASLDNGMSMMDVPTFWQYIVKGAILLLAVWMDSATKRR
                     S"
     gene            7091..8269
                     /gene="xylR"
                     /locus_tag="RN951_002653"
     CDS             7091..8269
                     /gene="xylR"
                     /locus_tag="RN951_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator XylR"
                     /protein_id="HDX2527634.1"
                     /translation="MFTKRHRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEED
                     FRARIDKIKDWLGDGVIADFDDKQIEQALADVDVPIVGVGGSYHLAESYPPVHYIATD
                     NYALVESAFLHLKEKGVNRFAFYGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGL
                     ETAPENWQHAQNRLADWLQTLPPQTGIIAVTDARARHILQVCEHLHIPVPEKLCVIGI
                     DNEELTRYLSRVALSSVAQGARQMGYQAAKLLHRLLDKEEMPLQRILVPPVRVIERRS
                     TDYRSLTDPAVIQAMHYIRNHACKGIKVDQVLDAVGISRSNLEKRFKEEVGETIHAMI
                     HAEKLEKARSLLISTTLSINEISQMCGYPSLQYFYSVFKKAYDTTPKEYRDVNSEVML
                     "
     gene            complement(8465..9289)
                     /locus_tag="RN951_002654"
     CDS             complement(8465..9289)
                     /locus_tag="RN951_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein bax"
                     /protein_id="HDX2527635.1"
                     /translation="MILTPIRRYGAMILMLLTLVFSSEVLAKTHTTTASQKSHLTKAS
                     NKQVSSKQEYSRNSAKSSSLPDLRKYPSGTPRKKAFLRTVMPYITSQNAAITAERNWL
                     ISKQYQGQWSPAERARLKDIAKRYKVKWSGNTRKIPWNTLLERVDIIPTSMVATMAAA
                     ESGWGTSKLARNNNNLFGMKCMKGRCTNAPGKVKGYSQFSSVKESVSAYVTNLNTHPA
                     YSSFRKSRAQLRKADQEVTATAMIHKLKGYSTKGKSYNNYLFAMYQDNQRLIAAHM"
     gene            9609..11639
                     /gene="malS"
                     /locus_tag="RN951_002655"
     CDS             9609..11639
                     /gene="malS"
                     /locus_tag="RN951_002655"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HDX2527636.1"
                     /translation="MKLAACFLTLLPGFAVAASWTSPGFPAFSEQGTGTFVSHAQLPK
                     GTRPLTLNFDQQCWQPADAIKLNQMLSLQPCSNTPPQWRLFRDGEYTLQIDTRSGTPT
                     LMISIQNAAEPVASLVRECPKWDGLPLTVDVSATFPEGAAVRDYYSQQIAIVKNGQIM
                     LQPAATSNGLLLLERAETDTSAPFDWHNATVYFVLTDRFENGDPSNDQSYGRHKDGMA
                     EIGTFHGGDLRGLTNKLDYLQQLGVNALWISAPFEQIHGWVGGGTKGDFPHYAYHGYY
                     TQDWTNLDANMGNEADLRTLVDSAHQRGIRILFDVVMNHTGYATLADMQEYQFGALYL
                     SGDEVKKSLGERWSDWKPAAGQTWHSFNDYINFSDKTGWDKWWGKNWIRTDIGDYDNP
                     GFDDLTMSLAFLPDIKTESTTASGLPVFYKNKMDTHAKAIDGYTPRDYLTHWLSQWVR
                     DYGIDGFRVDTAKHVELPAWQQLKTEASAALREWKKANPDKALDDKPFWMTGEAWGHG
                     VMQSDYYRHGFDAMINFDYQEQAAKAVDCLAQMDTTWQQMAEKLQGFNVLSYLSSHDT
                     RLFREGGDKAAELLLLAPGAVQIFYGDESSRPFGPTGSDPLQGTRSDMNWQDVSGKSA
                     ASVAHWQKISQFRARHPAIGAGKQTTLLLKQGYGFVREHGDDKVLVVWAGQQ"
     gene            11817..13070
                     /gene="avtA"
                     /locus_tag="RN951_002656"
     CDS             11817..13070
                     /gene="avtA"
                     /locus_tag="RN951_002656"
                     /EC_number="2.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--pyruvate transaminase"
                     /protein_id="HDX2527637.1"
                     /translation="MTFSLFGDKFTRHSGITLLMEDLNDGLRTPGAIMLGGGNPAQIP
                     EMQDYFQTLLTDMLESGKATDALCNYDGPQGKTELLTLLAGMLREKLGWDIEPQNIAL
                     TNGSQSAFFYLFNLFAGRRADGRVKKVLFPLAPEYIGYADAGLEEDLFVSARPNIELL
                     PEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELLKLDALANQHGIPLVID
                     NAYGVPFPGIIFSEARPLWNPNIVLCMSLSKLGLPGSRCGIIIANEKIITAITNMNGI
                     ISLAPGGIGPAMMCEMIKRNDLLRLSETVIKPFYYQRVQETIAIIRRYLPENRCLIHK
                     PEGAIFLWLWFKDLPITTEQLYQRLKARGVLMVPGHNFFPGLDKPWPHTHQCMRMNYV
                     PEPEKIEAGVKILAEEIERAWAESH"
     gene            complement(13221..13694)
                     /locus_tag="RN951_002657"
     CDS             complement(13221..13694)
                     /locus_tag="RN951_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDX2527638.1"
                     /translation="MNRFIIADATKCIGCRTCEVACAVSHHENQDCAALSPDEFISRI
                     RVIKDHCWTTAVACHQCEDAPCANVCPVDAISREHGHIFVEQTRCIGCKSCMLACPFG
                     AMEVVSSRKKARAIKCDLCWHRETGPACVEACPTKALQCMDVEKVQRHRLRQQPV"
     gene            complement(13796..14644)
                     /gene="yiaJ"
                     /locus_tag="RN951_002658"
     CDS             complement(13796..14644)
                     /gene="yiaJ"
                     /locus_tag="RN951_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator YiaJ"
                     /protein_id="HDX2527639.1"
                     /translation="MGKEVMGKKENEMAQEKERPAGSQSLFRGLMLIEILSNYPNGCP
                     LAHLSELAGLNKSTVHRLLQGLQSCGYVTTAPAAGSYRLTTKFIAVGQKALSSLNIIH
                     IAAPHLEALNIATGETINFSSREDDHAILIYKLEPTTGMLRTRAYIGQHMPLYCSAMG
                     KIYMAFGHPDYVKSYWESHQHEIQPLTRNTITELPAMFDELAHIRESGAAMDREENEL
                     GVSCIAVPVFDIHGRVPYAVSISLSTSRLKQVGEKNLLKPLRETAQAISNELGFTVRD
                     DLGAIT"
     gene            14845..15843
                     /gene="yiaK"
                     /locus_tag="RN951_002659"
     CDS             14845..15843
                     /gene="yiaK"
                     /locus_tag="RN951_002659"
                     /EC_number="1.1.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydro-L-gulonate 2-dehydrogenase"
                     /protein_id="HDX2527640.1"
                     /translation="MKVTFEQLKAAFNRVLISRGVDSETADACAEMFARTTESGVYSH
                     GVNRFPRFIQQLENGDIIPDAQPKRITSLGAIEQWDAQRSIGNLTAKKMMDRAIELAA
                     DHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLI
                     VAIPSTPITMVDMSMSMFSYGMLEVNRLAGRQLPVDGGFDDEGNLTKEPGVIEKNRRI
                     LPMGYWKGSGMSIVLDMIATLLSDGASVAEVTQDNSDEYGISQIFIAIEVDKLIDGPT
                     RDAKLQRIMDYVTSAERADENQAIRLPGHEFTTLLAENRRNGITVDDSVWAKIQAL"
     gene            15855..16322
                     /locus_tag="RN951_002660"
     CDS             15855..16322
                     /locus_tag="RN951_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HDX2527641.1"
                     /translation="MIFGHIAQPNPCRLPAAIEKALDFLRATDFNALEPGVVEIDGKN
                     IYTQIIDLTTREAVVNRPEVHRRYIDIQFLAWGEEKIGIAIDTGNNKVSESLLEQRNI
                     IFYHDSEHESFIEMIPGSYAIFFPQDVHRPGCIMQTASEIRKIVVKVALTALN"
     gene            16440..16913
                     /gene="yiaM"
                     /locus_tag="RN951_002661"
     CDS             16440..16913
                     /gene="yiaM"
                     /locus_tag="RN951_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate TRAP transporter small
                     permease YiaM"
                     /protein_id="HDX2527642.1"
                     /translation="MKKILEAILAINLAVLSCIVFINIILRYGFQTSILSVDELSRYL
                     FVWLTFIGAIVAFMDNAHVQVTFLVEKLSPAWQRRVALVTHSLILFICGALAWGATLK
                     TIQDWSDYSPILGLPIGLMYAACLPTSLVIAFFELRHLYQLITRSNSLTSPPQGA"
     gene            16916..18193
                     /gene="yiaN"
                     /locus_tag="RN951_002662"
     CDS             16916..18193
                     /gene="yiaN"
                     /locus_tag="RN951_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate transporter large permease
                     YiaN"
                     /protein_id="HDX2527643.1"
                     /translation="MAVLIFLGCLLGGIAIGLPIAWALLLCGAALMFWLDMFDVQIMA
                     QTLVNGADSFSLLAIPFFVLAGEIMNAGGLSKRIVDLPMKLVGHKPGGLGYVGVLAAM
                     IMASLSGSAVADTAAVAALLVPMMRSANYPVNRAAGLIASGGIIAPIIPPSIPFIIFG
                     VSSGLSISKLFMAGIAPGMMMGATLMLTWWWQASRLNLPRQQKATMQEIWHSFVSGIW
                     ALFLPVIIIGGFRSGLFTPTEAGAVAAFYALFVATVIYREMTFATLWHVLIGAAKTTS
                     VVMFLVASAQVSAWLITIAELPMMVSDLLQPLVDSPRLLFIVIMVAILIVGMVMDLTP
                     TVLILTPVLMPLVKEAGIDPIYFGVMFIINCSIGLITPPIGNVLNVISGVAKLKFDDA
                     VRGVFPYVLVLYSLLVVFVFIPDLIILPLKWIN"
     gene            18206..19192
                     /gene="yiaO"
                     /locus_tag="RN951_002663"
     CDS             18206..19192
                     /gene="yiaO"
                     /locus_tag="RN951_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate transporter
                     substrate-binding protein YiaO"
                     /protein_id="HDX2527644.1"
                     /translation="MKLRSVTYALFIAGLAAFSTSSLAAQSLRFGYETSQTDSQHIAA
                     KKFNDLLQERTKGELKLKLFPDSTLGNAQAMISGVRGGTIDMEMSGSNNFAGLSPVMN
                     LLDVPFLFRDTAHAHKTLDGKVGDDLKASLEGKGLKVLAYWENGWRDVTNSRAPVKTP
                     ADLKGLKIRTNNSPMNIAAFKVFGANPIPMPFAEVYTGLETRTIDAQEHPINVVWSAK
                     FFEVQKFLSLTHHAYSPLLVVINKAKFDGLSPEFQQALVSSAQEAGNYQRKLVAEDQQ
                     KIIDGMKEAGVEVITDLDRKAFSDALGNQVRDMFVKDVPQGADLLKAVDEVQ"
     gene            19196..20692
                     /gene="lyxK"
                     /locus_tag="RN951_002664"
     CDS             19196..20692
                     /gene="lyxK"
                     /locus_tag="RN951_002664"
                     /EC_number="2.7.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-xylulokinase"
                     /protein_id="HDX2527645.1"
                     /translation="MTQYWLGLDCGGSWLKAGLYDREGREAGVQRLPLCALSPQPGWA
                     ERDMAELWQCCMAVIRALLTHSGVSGEQIVGIGISAQGKGLFLLDKNDKPLGNAILSS
                     DRRAMEIVRRWQEDGIPEKLYPLTRQTLWTGHPVSLLRWLKEHEPERYAQIGCVMMTH
                     DYLRWCLTGVKGCEESNISESNLYNMSLGEYDPCLTDWLGIAEINHALPPVVGSAEIC
                     GEITAQTAALTGLKAGTPVVGGLFDVVSTALCAGIEDEFTLNAVMGTWAVTSGITRGL
                     RDGEAHPYVYGRYVNDGEFIVHEASPTSSGNLEWFTAQWGEISFDEINQAVASLPKAG
                     GDLFFLPFLYGSNAGLEMTSGFYGMQAIHTRAHLLQAIYEGVVFSHMTHLNRMRERFT
                     DVHTLRVTGGPAHSDVWMQMLADVSGLRIELPQVEETGCFGAALAARVGTGVYHNFSE
                     AQRDLRHPVRTLLPDMTAHQLYQKKYQRYQHLIAALQGFHARIKEHTL"
     gene            20689..21351
                     /gene="ulaD"
                     /locus_tag="RN951_002665"
     CDS             20689..21351
                     /gene="ulaD"
                     /locus_tag="RN951_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HDX2527646.1"
                     /translation="MSRPLLQLALDHSSLEAAQRDVTLLKDSVDIVEAGTILCLNEGL
                     GAVKALREQCPDKIIVADWKVADAGETLAQQAFGAGANWMTIICAAPLATVEKGHAMA
                     QRCGGEIQIELFGNWTLDDARDWHRIGVRQAIYHRGRDAQASGQQWGEADLARMKALS
                     DIGLELSITGGITPADLPLFKDIRVKAFIAGRALAGAANPAQVAGDFHAQIDAIWGGA
                     RA"
     gene            21344..22204
                     /locus_tag="RN951_002666"
     CDS             21344..22204
                     /locus_tag="RN951_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418039.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HDX2527647.1"
                     /translation="MRNHPLGIYEKALAKDLSWPERLVLAKSCGFDFVEMSVDETDER
                     LSRLDWSAAQRTSLVAAMIETGVGIPSMCLSAHRRFPFGSRDEAVRERAREIMSKAIR
                     LARDLGIRTIQLAGYDVYYEDHDEGTRQRFAEGLAWAVEQAAASQVMLAVEIMDTAFM
                     NSISKWKKWDEMLASPWFTVYPDVGNLSAWGNDVPAELKLGIDRIAAIHLKDTQPVTG
                     QSPGQFRDVPFGEGCVDFVGIFKTLHKLNYRGSFLIEMWTEKAKEPVLEIIQARRWIE
                     ARMQEAGFIC"
     gene            22198..22893
                     /gene="araD"
                     /locus_tag="RN951_002667"
     CDS             22198..22893
                     /gene="araD"
                     /locus_tag="RN951_002667"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDX2527648.1"
                     /translation="MLEQLKADVLAANLALPAHHLVTFTWGNVSAVDETRQWMVIKPS
                     GVEYDVMTADDMVVVEIASGKVVEGSKKPSSDTPTHLALYRRYAEIGGIVHTHSRHAT
                     IWSQAGLDLPAWGTTHADYFYGAIPCTRQMTAEEINGEYEYQTGEVIIETFEERGRSP
                     AQIPAVLVHSHGPFAWGKNAADAVHNAVVLEECAYMGLFSRQLAPQLPAMQNELLDKH
                     YLRKHGANAYYGQ"
     gene            complement(22925..23026)
                     /locus_tag="RN951_002668"
                     /pseudo
     CDS             complement(22925..23026)
                     /locus_tag="RN951_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312484.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            23030..23218
                     /locus_tag="RN951_002669"
                     /pseudo
     CDS             23030..23218
                     /locus_tag="RN951_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(23240..23980)
                     /locus_tag="RN951_002670"
     CDS             complement(23240..23980)
                     /locus_tag="RN951_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MipA/OmpV family protein"
                     /protein_id="HDX2527649.1"
                     /translation="MLINRNIVALFSLPFMASATASELSIGAGAAYNESPYRGYNENT
                     KAIPLISYEGDTFYVRQTTLGFILSQSEKNELSLTASWMPLEFDPTDNDDYAMQQLDK
                     RDSTAMAGVAWYHHERWGTVKASAAADVLDNSNGWVGELSVFHKMQIGRLSLTPALGV
                     LYYDENFSDYYYGISESESRRSGLASYSAQDAWVPYVSLTAKYPIGEHVVLMASAGYS
                     ELPEEITDSPMIDRNESFTFVTGVSWRF"
     gene            24104..25078
                     /locus_tag="RN951_002671"
     CDS             24104..25078
                     /locus_tag="RN951_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX2527650.1"
                     /translation="MTKLQLKYRELKIISVIAASENISHAATVLGIAQANVSKYLADF
                     ESKVGLKVFDRTTRQLMLTPFGTALLPYINDMLDRNEQLNNFIADYKHEKRGRVTIYA
                     PTGIITYLSKHVIDKIKDIGDITLSLKTCNLERNAFYEGVEFPDDCDVLISYAPPKDE
                     SLVASFITQYAVTAYASQRYLEKHPISRPDELEHHSCILIDSMMIDDANIWRFNVAGS
                     KEVRDYRVKGNYVCDNTQSALELARNHLGIVFAPDKSVQSDLQDGTLVPCFQQPYEWW
                     LDLVAIFRKREYQPWRVQYVLDEMLREIRHQLAQSQQLRPEQAAESED"
     gene            complement(25075..26211)
                     /locus_tag="RN951_002672"
     CDS             complement(25075..26211)
                     /locus_tag="RN951_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HDX2527651.1"
                     /translation="MDLLIILTYVAFAWAMFKIFKIPVNKWTIPTAALGGIFIVSGLI
                     LLMNYNHPYTFKAQKAVISIPVVPQVTGVVIEVTDKKNTLIKKGEVLFRLDPTRYQAR
                     VDRLMADIVTAEHKQRALGAELDEMAANTQQAKATRDKFAKEYQRYARGSQAKVNPFS
                     ERDIDVARQNYLAQEASVKSSAAEQKQIQSQLDSLVLGEHSQIASLKAQLAEAKYNLE
                     QTIVRAPSDGYVTQVLIRPGTYAASLPLRPVMVFIPDQKRQIVAQFRQNSLLRLAPGD
                     DAEVVFNALPGKVFSGKLAAISPAVPGGAYQSTGTLQTLNTAPGSDGVIATIELDEHT
                     DLSALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWVHYLYLDH"
     gene            complement(26217..26540)
                     /locus_tag="RN951_002673"
     CDS             complement(26217..26540)
                     /locus_tag="RN951_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3302 domain-containing protein"
                     /protein_id="HDX2527652.1"
                     /translation="MFLDYFALGVLIFVFLVIFYGIIILHDIPYLIAKKRNHPHADAI
                     HVAGWVSLFTLHVIWPFLWIWATLYRPERGWGMQSHDSSVMQLQQRIAGLEKQLADIK
                     SSSAE"
     gene            26723..26866
                     /locus_tag="RN951_002674"
     CDS             26723..26866
                     /locus_tag="RN951_002674"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527653.1"
                     /translation="MNNSSKTSTVQIKRIKPSIIYRLLLIGLGSPMVIYGLVRPLTIE
                     TRD"
     gene            complement(27085..28623)
                     /gene="aldB"
                     /locus_tag="RN951_002675"
     CDS             complement(27085..28623)
                     /gene="aldB"
                     /locus_tag="RN951_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001551836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase AldB"
                     /protein_id="HDX2527654.1"
                     /translation="MTNNPPSAQIKPGEYGFPLKLKARYDNFIGGEWVAPADGEYYQN
                     LTPVTGQLLCEVASSGKRDIDLALDAAHKVKDKWAHTSVQDRAAILFKIADRMEQNLE
                     LLATAETWDNGKPIRETSAADVPLAIDHFRYFASCIRAQEGGISEVDSETVAYHFHEP
                     LGVVGQIIPWNFPLLMASWKMAPALAAGNCVVLKPARLTPLSVLLLMEIVGDLLPPGV
                     VNVVNGAGGVIGEYLATSKRIAKVAFTGSTEVGQQIMQYATQNIIPVTLELGGKSPNI
                     FFADVMDEEDAFFDKALEGFALFAFNQGEVCTCPSRALVQESIYERFMERAIRRVESI
                     RSGNPLDSVTQMGAQVSHGQLETILNYIDIGKKEGADVLTGGRRKLLEGELKDGYYLE
                     PTILFGQNNMRVFQEEIFGPVLAVTTFKTMEEALELANDTQYGLGAGVWSRNGNLAYK
                     MGRGIQAGCVWTNCYHAYPAHAAFGGYKQSGIGRETHKMMLEHYQQTKCLLVSYSDKP
                     LGLF"
     gene            complement(28788..29939)
                     /gene="yiaY"
                     /locus_tag="RN951_002676"
     CDS             complement(28788..29939)
                     /gene="yiaY"
                     /locus_tag="RN951_002676"
                     /EC_number="1.1.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine dehydrogenase"
                     /protein_id="HDX2527655.1"
                     /translation="MAASTFFIPSVNVIGADSLTDAMNMMADYGFTRTLIVTDNMLTK
                     LGMAGDVQKALEERNIFSVIYDGTQPNPTTENVAAGLKLLKENNCDSVISLGGGSPHD
                     CAKGIALVAANGGDIRDYEGVDRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIK
                     MAIVDKHVTPLLSVNDSSLMIGMPKSLTAATGMDALTHAIEAYVSIAATPITDACALK
                     AVTMIAENLPLAVEDGSNAKAREAMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYNLP
                     HGVCNAVLLPHVQVFNSKVAAARLRDCAAAMGVNVTGKNDAEGAEACINAIRELAKKV
                     DIPAGLRDLNVKEEDFAVLATNALKDACGFTNPIQATHEEIVAIYRAAM"
BASE COUNT         7449 a         7755 c         7504 g         7332 t
ORIGIN      
        1 ccccacccgg tcaggcaggg gataacgttt acgccattaa tggcagaagt tgctgataga
       61 ggcgacggaa cgtttctcgt cgtggctgat aagcggcata acgctgcgca tctggtagat
      121 gcgactgttc taacggtagt tgcggcaaca attcaatgag cgatttctct ggattcgccg
      181 cgatctgcgc cagccttgct gcgcccagtg ctggccccac atcccccccc gtacggtaat
      241 cgagctgctg accgctgata tccgccagca tctgacgcca gtactcacta cgcgccccgc
      301 ccccaatcaa cgtaacactt tgcggtttaa taccgcaggc atgcacgaca tccatgccat
      361 ctgccagcgc ataacccacg ccttccagca ctgctcgcgc cagttcattg gggccatgtt
      421 gatgagtcaa accaaagaaa acccccttcg cctggggatt attgtgtggc gtacgctcgc
      481 cggaaagata aggcagaaac caaactggct cggcactttc atcagcctgt tgagctgcag
      541 cgattaaagc tgggacattg ctcaggccgg ttaatttcgc ggcccaatcc agacacgacg
      601 ctgcactcag catcacagac attaaatgcc aacgttgcgg tagcgcatgg caaaagctat
      661 gtacggcgct ttctggcttg cttaagaacc cttcgctgac agcaaaatag acccccgacg
      721 tccccagcga taacattgcc tgattagcat caaccattcc cacaccaact gcaccagctg
      781 cattgtcgcc accgcctgcg acaactggca ccgtcgccat accccacgct ttcgcaactt
      841 caggtaacaa agcaccagta atttcgctgc cttcgtataa tgcgggcatc tggtcacgag
      901 ataagtcgca agcctgcagc atgacgtcac tccagtcacg ctttgcgaca tccagccaca
      961 tggtgccagc tgcgtcagac atatcgctgg caaactcccc cgtcatacgc agacgcaagt
     1021 aatctttcgg taataatact ttgtcgattt gacggaatat ctccggctca tgccgctgaa
     1081 cccatagcaa tttaggcgca gtaaatccgg gcatcatcag gttgccggta atcacccgcg
     1141 attgcggaac tcgcgcttcc agcaaagtgc actcttgcgc acagcgcccg tcgttccaca
     1201 aaatggcagg gcgtaacacc cgttgctgag catccagcaa ggttgctccg tgcatctggc
     1261 cggcaatacc caatgcttta acgtcctgca gagaatgctg atcgcccaga gctttcattg
     1321 cgcgatcagt tgcctgccac cactgttccg ggtcttgttc cgaccagagt ggatgcgggc
     1381 gcgaaacggt cagcttttcc gtttgcgcag caaccacctc accctgctcg ttgagcaaaa
     1441 taacttttac gcccgaggtg ccaagatcta tcccgatata catatcgatc gttccttaaa
     1501 aaaatgcccg gtatcgctac cgataaccgg gccaacggac tgcacagtta gccgttattt
     1561 gtcgaacaga taatggttta ccagattttc cagttgttcc tggcgaccac tctgatgcac
     1621 cggagacaaa tgatgttcct gagcatattt ggctaaatct gccagtgaca tttggccttt
     1681 caggatttgc tggcccaatt cgctattcca gccggaataa cgctgcgcga tgcgtttatc
     1741 cagctcgcca tcttcaatca tgcgcgctgc aattttcagc gccagtgcca tcgtatccat
     1801 cgcgccgata tgaccgtaaa acagatcata tttatcagta ctttgacgac gtactttggc
     1861 atcgaagttc agaccaccgg tggtgaaacc gcctgctttg agaatttcat acatcaccag
     1921 cgcattctct tccacactgt tcgggaactg gtcggtgtcc cagcccagtt gcgcatcgcc
     1981 acggttggcg tcgacagaac cgaacaggcc aagcgcaatg gcggtggcta tttcatgatg
     2041 gaaagagtga cctgccagcg tcgcgtggtt agcttcaatg ttcagtttaa tctctttttc
     2101 cagaccaaac tgtttcagga agccatagac cgtcgcggca tcgtaatcat attgatgttt
     2161 ggtcggttct tgcggtttcg gttcgataag caacgtgccc tggaaaccga ttttatgttt
     2221 atgctcaacc accatctgca taaagcggcc cagttgttca cgctcctgac gcaagtcggt
     2281 atttaacagc gtttcgtaac cttcacgacc gccccacagg acatagtttt caccgcccaa
     2341 tttatgggtt gcttccatcg ctgtaacaac ttgcgttgcc gcccagctga agacttcagg
     2401 atctgggttc gtcgccgcac ccgcgccgta gcgagggttt gtaaagcagt tggcggttcc
     2461 ccacagcagc ttcacgccgc tctcttcttg cttgcctgcc aggacatcaa ccatttgcgc
     2521 aaaattattg atgtactctt ttaacgacgc gccctcaggg gaaacatcca catcgtggaa
     2581 gcaataaaat ggcacatgta acttgtggaa aaactcaaat gcgacatctg ctttacgctt
     2641 cgccaacgcc agtgcctcac caggctgctg ccacggacga ttaaacgccc ccacaccaaa
     2701 catatccgcc ccgttccagc agaaggtgtg ccagtagcag gcggcaaaac gcaagtgctc
     2761 ttccatacgc ttacccaaca ccagttcgtc gggattgtag tgacggaatg ctaacgggtt
     2821 tgaggatttt gagccttcat aacgaacgcg atcgagctgg tcaaaatagg cttgcatatt
     2881 gaactccata atcaggtaat gccgcgggtg atggatgatg tcgtaatatt gggcactccc
     2941 tttcagttgc tcaattatgt tatttcacac tgctattgag ataattcaca agtgtgcgct
     3001 cgctcgcaaa ataaaatgga atgatgaaac tgggtaattc ctcgaagaga aaaatgcaat
     3061 aagtacaatt gcgcaacaaa agtaagatct cggtcataaa tcaagaaata aaccaaaaat
     3121 cgtaatcgaa agataaaaat ctgtaattgt tttcccctgt ttagttgcta aaaattggtt
     3181 acgtttatcg cggtgattgt tacttattaa aactgtcctc taactacaga aggccctaca
     3241 ccatgaaaat aaagaacatt ctactcaccc tttgcacctc actcctgctt accaacgttg
     3301 ctgcacacgc caaagaagtc aaaataggta tggcgattga tgatctccgt cttgaacgct
     3361 ggcaaaaaga tcgagatatc tttgtgaaaa aggcagaatc tctcggcgcg aaagtatttg
     3421 tacagtctgc aaatggcaat gaagaaacac aaatgtcgca gattgaaaac atgataaacc
     3481 ggggtgtcga tgttcttgtc attattccgt ataacggtca ggtattaagt aacgttgtaa
     3541 aagaagccaa acaagaaggc attaaagtat tagcttacga ccgtatgatt aacgatgcgg
     3601 atatcgattt ttatatttct ttcgataacg aaaaagtcgg tgaactgcag gcaaaagccc
     3661 tggtcgatat tgttccgcaa ggtaattact tcctgatggg cggctcgccg gtagataaca
     3721 acgccaagct gttccgcgcc ggacaaatga aagtgttaaa accttacgtt gattccggaa
     3781 aaattaaagt cgttggtgac caatgggttg atggctggtt accggaaaac gcattgaaaa
     3841 ttatggaaaa cgcgctaacc gccaataata acaaaattga tgctgtagtt gcctcaaacg
     3901 atgccaccgc aggtggggca attcaggcat taagcgcgca aggtttatca gggaaagtag
     3961 caatctcagg ccaggatgcg gatctcgcag gtattaaacg tattgctgcc ggtacgcaaa
     4021 ctatgacggt gtataaacct attacgttgt tggcaaatac tgccgcagaa attgccgttg
     4081 agttgggcaa tggtcaggaa ccaaaagcag ataccacact gaataatggc ctgaaagatg
     4141 tcccctcccg cctcctgaca ccgatcgatg tgaataaaaa caacatcaaa gatacggtaa
     4201 ttaaagacgg attccacaaa gagagcgagc tgtaagcgtt acgccccagc gcggagcggg
     4261 ggcgtgattt ctctccatgc cgcgtgaatg aattggctta ggtggagtcg ttatgcctta
     4321 tctacttgaa atgaagaaca ttaccaaaac cttcggcagt gtgaaggcga ttgataacgt
     4381 ctgcttgcgg ttgaatgctg gcgaaatcgt ctcactttgt ggggaaaatg ggtctggtaa
     4441 atcaacgctg atgaaagtgc tgtgtggtat ttatccccat ggctcctacg aaggcgaaat
     4501 tatttttgcg ggagaagaga ttcaggcgag tcacatccgc gataccgaac gcaaaggtat
     4561 cgccatcatt catcaggaat tggccctggt gaaagaattg accgtgctgg aaaatatctt
     4621 cctgggtaac gaaataaccc acaatggcat tatggattat gacctgatga cgctacgctg
     4681 tcagaagctg ctcgcacagg tcagtttatc catttcacct gatacccgcg ttggcgattt
     4741 agggcttggg caacaacaac tggttgaaat tgccaaggca cttaataaac aggtgcgctt
     4801 gttaattctc gatgaaccga cagcctcatt aactgagcag gaaacgtcgg ttttactgga
     4861 tattattcgc gatctacaac agcacggtat cgcctgtatt tatatttcgc acaaactcaa
     4921 cgaagtcaaa gcgatttccg atacgatttg cgttattcgc gacggacagc acattggtac
     4981 gcgtgatgct gccggaatga gtgaagacga tattatcacc atgatggtcg ggcgagagtt
     5041 aaccgcgctt taccctaatg aaccacatac caccggagat gaaatattac gtattgaaca
     5101 tctgacggca tggcatccgg ttaatcgtca tattaaacga gttaatgatg tctcgttttc
     5161 cctgaaacgt ggcgaaatat tgggtattgc cggactcgtt ggtgccggac gtaccgagac
     5221 cattcagtgc ctgtttggtg tgtggcccgg acaatgggaa ggaaaaattt atattgatgg
     5281 caaacaggta gatattcgta actgtcagca agccatcgcc caggggattg cgatggtccc
     5341 cgaagacaga aagcgcgacg gcatcgttcc ggtaatggcg gttggtaaaa atattaccct
     5401 cgccgcactc aataaattta ccggtggcat tagccagctt gatgacgcgg cagagcaaaa
     5461 atgtattctg gaatcaatcc agcaactcaa agttaaaacg tcgtcccccg accttgctat
     5521 tggacgtttg agcggcggca atcagcaaaa agcgatcctc gctcgctgtc tgttacttaa
     5581 cccgcgcatt ctcattcttg atgaacccac caggggtatc gatattggcg cgaaatacga
     5641 gatctacaaa ttaattaacc aactcgtcca gcagggtatt gccgttattg tcatctcttc
     5701 cgaattacct gaagtgctcg gccttagcga tcgtgtactg gtgatgcatg aagggaaact
     5761 aaaagccaac ctgataaatc ataacctgac tcaggagcag gtgatggaag ccgcattgag
     5821 gagcgaacat catgtcgaaa agcaatccgt ctgaagtgaa attggccgta ccgacatccg
     5881 gtggcttctc cgggctgaaa tcactgaatt tgcaggtctt cgtgatgatt gcagctatca
     5941 tcgcaatcat gctgttcttt acctggacca ccgatggtgc ctacttaagc gcccgtaacg
     6001 tctccaacct gttacgccag accgcgatta ccggcatcct cgcggtagga atggtgttcg
     6061 tcataatttc tgctgaaatc gacctttccg tcggctcaat gatggggctg ttaggtggcg
     6121 tcgcggcgat ttgtgacgtc tggttaggct ggcctttgcc acttaccatc attgtgacgc
     6181 tggttctggg actgcttctc ggtgcctgga acggatggtg ggtcgcgtac cgtaaagtcc
     6241 cttcatttat tgtcaccctc gcgggcatgt tggcatttcg cggcatactc attggcatca
     6301 ccaacggcac gactgtatcc cccaccagcg ccgcgatgtc acaaattggg caaagctatc
     6361 tccccgccag taccggcttc atcattggcg cgcttggctt aatggctttt gttggttggc
     6421 aatggcgcgg aagaatgcgc cgtcaggctt tgggtttaca gtctccggcc tctaccgcag
     6481 tagtcggtcg ccaggcttta accgctatca tcgtattagg cgcaatctgg ctgttgaatg
     6541 attaccgtgg cgttcccact cctgttctgc tgctgacgtt gctgttactc ggcggaatgt
     6601 ttatggcaac gcggacggca tttggacgac gcatttatgc catcggcggc aatctggaag
     6661 cagcacgtct ctccgggatt aacgttgaac gcaccaaact tgccgtgttc gcgattaacg
     6721 gattaatggt agccatcgcc ggattaatcc ttagttctcg acttggcgct ggttcacctt
     6781 ctgcgggaaa tatcgccgaa ctggacgcaa ttgcagcatg cgtgattggc ggcaccagcc
     6841 tggctggcgg tgtgggaagc gttgccggag cagtaatggg ggcatttatc atggcttcac
     6901 tggataacgg catgagtatg atggatgtac cgaccttctg gcagtatatc gttaaaggtg
     6961 cgattctgtt gctggcagta tggatggact ccgcaaccaa acgccgttct tgattttgat
     7021 aaaaattttc tcaaagccgg ttacgtatta ccggttttga gtttttgcat gattcagcag
     7081 gaaaagaacc atgtttacta aacgtcaccg catcacatta ctgttcaatg ccaataaagc
     7141 ctatgaccgg caggtagtag aaggcgtagg ggaatattta caggcgtcac aatcggaatg
     7201 ggatattttc attgaagaag atttccgcgc ccgcattgat aaaatcaagg actggttagg
     7261 agatggcgtc attgccgact tcgacgacaa acagatcgag caagcgctgg ctgatgtcga
     7321 cgtccccatt gttggggttg gcggctcgta tcaccttgca gaaagttacc cacccgttca
     7381 ttacattgcc accgataact atgcgctggt tgaaagcgca tttttgcatt taaaagagaa
     7441 aggcgttaac cgctttgctt tttatggtct tccggaatca agcggcaaac gttgggccac
     7501 tgagcgcgaa tatgcatttc gtcagcttgt cgccgaagaa aagtatcgcg gagtggttta
     7561 tcaggggtta gaaaccgcgc cagagaactg gcaacacgcg caaaatcggc tggcagactg
     7621 gctacaaacg ctaccaccgc aaaccgggat tattgccgtt actgacgccc gagcgcggca
     7681 tattctgcaa gtatgtgaac atctacatat tcccgtaccg gaaaaattat gcgtgattgg
     7741 catcgataac gaagaactga cccgctatct gtcgcgtgtc gccctttctt cggtcgctca
     7801 gggcgcgcgg caaatgggct atcaggcggc aaaactgttg catcgattat tagataaaga
     7861 agaaatgccg ctacagcgaa ttttggtccc accagttcgc gtcattgaac ggcgctcaac
     7921 agattatcgc tcgctgaccg atcccgccgt tattcaggcc atgcattaca ttcgtaatca
     7981 cgcctgtaaa gggattaaag tggatcaggt actggatgcg gtcgggatct cgcgctccaa
     8041 tcttgagaag cgttttaaag aagaggtggg tgaaaccatc catgccatga ttcatgccga
     8101 gaagctggag aaagcgcgca gtctgctgat ttcaaccacc ttgtcgatca atgagatatc
     8161 gcaaatgtgc ggttatccat cgctgcaata tttctactct gtttttaaaa aagcatatga
     8221 cacgacgcca aaagagtatc gcgatgtaaa tagcgaggtc atgttgtagc gatgatgaga
     8281 attgtcggcg tcacatcagg taacgctgcg tggttgtcgg atgcggcgtg aacgccttat
     8341 ccgacctacc cgccaggcat gataaaacgc accaacaacg cttcaggctc gtagctcaac
     8401 tgcctgagac aaagtaaaaa gccttatccg actgacaagt cggataaggc tcaaggaaat
     8461 gcaattacat atgcgccgcg attaaccgtt ggttatcctg gtacattgcg aacaggtagt
     8521 tgttataact cttccctttg gtcgagtagc ccttcagctt gtgaatcatc gctgtggcag
     8581 tcacttcctg atccgcttta cgcagctgcg cacgcgattt acggaacgaa gagtaagccg
     8641 ggtgcgtatt caggttagtg acataggcgc tcaccgattc tttgacagaa ctaaactgtg
     8701 agtacccttt cactttacct ggcgcattgg tacaacgtcc tttcatgcat ttcatgccga
     8761 acaggttgtt gttgttgcgc gccagcttcg acgttcccca accgctttct gctgcagcca
     8821 tcgtcgccac catactggtg gggataatgt ctacgcgttc aagcaaggta ttccacggga
     8881 tttttcgcgt attaccggac cacttcacct tgtagcgttt ggcgatgtct ttcagacgcg
     8941 cacgctcagc aggtgaccat tggccctgat actgttttga aatgagccag ttacgttccg
     9001 cagtaatggc cgcattttgg ctggtaatgt aaggcattac ggtccggaga aacgcctttt
     9061 tccttggtgt tccggaaggg tattttcgca aatcaggaag tgaactactc tttgcactat
     9121 tgcgagaata ctcttgttta ctgcttacct gtttattact agctttagtt aagtgggact
     9181 tttgactcgc tgttgttgtg tgcgtcttcg ctaacacctc actcgaaaac accagagtga
     9241 gtaacataag aatcatcgcc ccatatcgtc gtatgggagt caaaatcatc aggtctcctg
     9301 gtcggattta atcattccaa caccttatat ttttcacaaa tttgagagtt gaatctcaaa
     9361 tcatatcaaa aatagctgtc aagagcaccc caaggaatag tccaaatctg aaactatgtc
     9421 acgtgttaac gattcagatt ggcgctaaat cgcagaaaat gtgggggtta tcgcaaaatt
     9481 cagccgtttt ttgcgcgaga tcgctcaccc ttgcttctca tcctgtggac ttaccgctca
     9541 gggatgagtt ttgtttggct tatcgctggc aaactgtctg aaatcgcagc aataaggact
     9601 catccgccat gaaactcgcc gcctgttttc tgacactcct tcctggcttc gccgttgccg
     9661 ccagctggac ttctccgggg tttcccgcct ttagcgaaca ggggacagga acatttgtca
     9721 gccacgcgca gttgcccaaa ggtacgcgtc cactaacgct aaattttgac caacagtgct
     9781 ggcagcctgc ggatgcgata aaactcaatc agatgctttc cctgcaacct tgtagcaaca
     9841 cgccgcctca atggcgattg ttcagggacg gcgaatatac gctgcaaata gacacccgct
     9901 ccggtacgcc aacattgatg atttccatcc agaacgccgc cgaaccggta gcaagcctgg
     9961 tccgtgaatg cccgaaatgg gatggattac cgctcacagt ggatgtcagc gccactttcc
    10021 cggaaggagc cgccgtacgg gattattaca gccagcaaat tgcgatagtg aagaacggtc
    10081 aaataatgtt acaacccgct gccaccagca acggtttact cctgctggaa cgggcagaaa
    10141 ctgacacatc cgcccctttc gactggcata acgccacggt ttactttgtg ctgacagatc
    10201 gtttcgaaaa cggcgatccc agtaatgacc agagttacgg acgtcataaa gacggtatgg
    10261 cggaaattgg cacttttcac ggcggcgatt tacgcggcct gaccaacaaa ctggattacc
    10321 tccagcagtt gggcgttaat gctttatgga taagcgcccc atttgagcaa attcacggct
    10381 gggtcggcgg cggtacaaaa ggcgatttcc cgcattatgc ctaccacggt tattacacac
    10441 aggactggac gaatcttgat gccaatatgg gcaacgaagc cgatctacgg acgctggttg
    10501 atagcgcaca tcagcgcggt attcgtattc tctttgatgt cgtgatgaac cacaccggct
    10561 atgccacgct ggcggatatg caggagtatc agtttggcgc gttatatctt tctggtgacg
    10621 aagtgaaaaa atcgctgggt gaacgctgga gcgactggaa acctgccgcc gggcaaacct
    10681 ggcatagctt taacgattac attaatttca gcgacaaaac aggctgggat aaatggtggg
    10741 gaaaaaactg gatcagaacg gatatcggcg attacgacaa tcctggattc gacgatctca
    10801 ctatgtcgct agcctttttg ccggatatca aaaccgaatc aactaccgct tctggtctgc
    10861 cggtgttcta taaaaacaaa atggataccc acgccaaagc cattgacggc tatacgccgc
    10921 gcgattactt aacccactgg ttaagtcagt gggtccgcga ctatgggatt gatggttttc
    10981 gggtcgatac cgccaaacat gttgagttgc ccgcctggca gcaactgaaa accgaagcca
    11041 gcgccgcgct tcgcgaatgg aaaaaagcta accccgacaa agcattagat gacaaacctt
    11101 tctggatgac cggtgaagcc tggggccacg gcgtgatgca aagtgactac tatcgccacg
    11161 gcttcgatgc gatgatcaat ttcgattatc aggagcaggc ggcgaaagca gtcgactgtc
    11221 tggcgcagat ggatacgacc tggcagcaaa tggcggagaa attgcagggt ttcaacgtgt
    11281 tgagctacct ctcgtcgcat gatacccgcc tgttccgtga agggggcgac aaagcagcag
    11341 agttattact attagcgcca ggcgcggtac aaatctttta tggtgatgaa tcctcgcgtc
    11401 cgttcggtcc tacaggttct gatccgctgc aaggtacacg ttcggatatg aactggcagg
    11461 atgttagcgg taaatctgcc gccagcgtcg cgcactggca gaaaatcagc cagttccgcg
    11521 cccgccatcc cgcaattggc gcgggcaaac aaacgacact tttgctgaag cagggctacg
    11581 gctttgttcg tgagcatggc gacgataaag tgctggtcgt ctgggcaggg caacagtaac
    11641 ttttccggct tcccgttcgt cagtacctcg ggaagccgcc aaccaggata aaatgtcagc
    11701 cctaatcagc gttgcaggat aaagcaccgc tcactcttca acagaccgat ttgcacccca
    11761 gcaaatgtag cgttattgtt accttccttg ctacagagtt cgacagatat cccgctatga
    11821 cattctccct ttttggtgac aaatttaccc gccactccgg cattacgctg ttgatggaag
    11881 atctgaacga cggtttacgc acgcctggcg cgattatgct cggcggcggt aatccggcgc
    11941 agatcccgga aatgcaggac tacttccaga cgctactgac cgacatgctg gaaagtggca
    12001 aagcgactga tgcactgtgt aactacgacg gtccacaggg gaaaacggag ctactcacac
    12061 tgcttgccgg aatgctgcgc gagaagttgg gttgggatat cgaaccacag aatattgcac
    12121 taacaaacgg cagccagagc gcgtttttct acttatttaa cctgtttgcc ggacgccgtg
    12181 ccgatggtcg ggtcaaaaaa gtgctgttcc cgcttgcacc ggaatacatt ggctatgctg
    12241 acgccggact ggaagaagat ctgtttgtct ctgcgcgtcc gaatattgaa ctgctgccgg
    12301 aaggccagtt taaataccac gtcgattttg agcatctgca tattggcgaa gaaaccggga
    12361 tgatttgcgt ctcccggccg acgaatccaa caggcaatgt gattactgac gaagagttgc
    12421 tgaagcttga cgcgctggcg aatcaacacg gcattccgct ggtgattgat aacgcttatg
    12481 gcgtcccgtt cccgggtatc atcttcagtg aagcgcgccc gctatggaat ccgaatatcg
    12541 tgctgtgcat gagtctttcc aagctgggtc tacctggctc ccgctgcggc attatcatcg
    12601 ccaatgaaaa aatcatcacc gccatcacca atatgaacgg cattatcagc ctggcacctg
    12661 gcggtattgg tccggcgatg atgtgtgaaa tgattaagcg taacgatctg ctgcgcctgt
    12721 ctgaaacagt catcaaaccg ttttactacc agcgtgttca ggaaactatc gccatcattc
    12781 gccgctattt accggaaaat cgctgcctga ttcataaacc ggaaggagcc attttcctct
    12841 ggctatggtt taaggatttg cccattacga ccgagcagct ctatcagcgc ctgaaagcac
    12901 gcggcgtgct gatggtgccg gggcacaact tcttcccagg gctggataaa ccgtggccgc
    12961 atacgcatca atgtatgcgc atgaactacg taccagagcc ggagaaaatt gaggcggggg
    13021 tgaagattct ggcggaagag atagaaagag cctgggctga aagtcactaa aaattgcctg
    13081 atgcgctacg cttatcaggc ctacatgatt tctgcaatat attgaatttg gaagaatttg
    13141 taggccggat aaggcgttta cgccgcatct ggcataaaca aagcgcactg ttccggcgtt
    13201 gagaaacgcc ggaaaacgtt tcaaacaggc tgctgccgta gccgatgccg ctgcactttc
    13261 tcgacatcca tgcactgcaa cgcctttgtc gggcaggctt caacacaggc cggtcccgtc
    13321 tcccgatgcc agcacagatc gcacttaatc gccctcgcct ttttgcgcga agaaacgacc
    13381 tccatcgcac caaacgggca agccagcata cagcttttac agccaatgca acgtgtttgt
    13441 tcaacgaaaa tatgcccatg ttcgcggctt atcgcgtcaa cagggcagac attcgcgcac
    13501 ggtgcatctt cacactgatg acaggctact gccgtggtcc agcagtggtc tttaatgaca
    13561 cgaatacggg aaataaactc gtctggtgac aacgcagcgc aatcctgatt ctcatgatgc
    13621 gacactgcgc aagccacttc acaggtacgg caaccgatac atttcgtcgc atccgcaata
    13681 ataaaccggt tcatgatcac tcctttgcac taaaacagca gagtgccaga gagcgcgtcc
    13741 ctactgcttt gatccaacga aggaaatgtt aaagttttgg cacttgtcca aagcgttatg
    13801 tgatcgcgcc caggtcatcc ctgacagtaa atcccagttc attagaaata gcctgcgcgg
    13861 tttcacgcag tggtttcagg agatttttct ctcccacctg tttcagacgt gatgtcgaaa
    13921 gcgaaatcga cacggcgtac ggcacccgcc catgaatatc aaacaccgga acagcaatac
    13981 aggagacgcc gagttcgttt tcttctctgt ccatcgccgc tccgctttca cgaatgtgcg
    14041 ccagttcgtc gaacatcgcg ggcagctcgg taatggtatt gcgggttaac ggctggatct
    14101 catgctgatg gctttcccag tatgacttca cgtagtccgg gtgaccaaac gccatgtaga
    14161 tcttgcccat tgcggaacag tagagcggca tatgctggcc aatataggca cgggttcgca
    14221 gcatcccggt tgtgggttcc agcttataaa tcaaaatagc gtgatcgtct tcgcggctgg
    14281 agaagttaat ggtttcacca gtggcgatgt tcagtgcctc aagatgcgga gcggcgatat
    14341 gaatgatatt cagcgaagac agcgccttct gcccgacggc aataaatttg gtggtcaggc
    14401 gataactccc tgcggcaggc gcggtggtca catagccgca ggactgtaat ccctgcaata
    14461 agcgatggac ggtactctta tttaaaccag ccagctccga aagatgcgcc aacggacaac
    14521 cgtttggata gttgctcaaa atctcaatca gcatcaaccc gcgaaacaga ctctggcttc
    14581 cggctggacg ctctttttcc tgcgccatct cgttctcttt ttttcccatc acttctttcc
    14641 ccattttgtc gcgtcctgat ggtagcgcaa agtgtgccgt agttcacgat ctcgacagat
    14701 aatttataac caattgattt ttatgtcttt tgaaattcat caatcagatt gctttgttaa
    14761 aaagtgatcg atatatttga aatcaagttt cgcatattga aattttaagc caaaaaagcg
    14821 atcaaaaaaa caaggaagcc tgggatgaaa gtgacatttg agcagttaaa agcagccttt
    14881 aatcgggtct taatttcacg cggcgttgac agcgaaacgg ctgacgcctg tgcagagatg
    14941 ttcgcccgca ccaccgaatc cggcgtttat tctcacggcg ttaatcgttt ccctcgtttc
    15001 attcaacaac tggaaaacgg cgatatcatt cctgatgccc aacccaaacg tataaccagc
    15061 ctcggcgcaa ttgaacagtg ggacgcccag cgttcgatcg gtaacctgac agcgaaaaag
    15121 atgatggatc gcgccattga actggctgcc gatcacggta ttggtctggt ggcactacgt
    15181 aatgccaacc actggatgcg cggcggcagc tacggctggc aggcggcgga aaaaggctat
    15241 attggcattt gctggaccaa ctccatcgcc gtaatgccgc cgtggggcgc aaaagagtgt
    15301 cgcatcggca ctaacccgct gatcgtcgcc attccttcca cgccgatcac catggtcgat
    15361 atgtcgatgt cgatgttctc ttacggcatg ttagaagtta accgtctggc aggtcgtcag
    15421 ctcccggtcg atggtggctt tgatgatgag ggcaatttga ccaaagaacc tggcgttatc
    15481 gagaagaatc gccgcatttt gccgatggga tactggaaag gttctggcat gtcgattgtg
    15541 ctggatatga tcgctactct cctttccgac ggcgcatccg ttgccgaagt cacccaggac
    15601 aacagcgacg aatacggcat ttcacaaatt tttattgcca ttgaagtgga caagcttatc
    15661 gacggtccca cccgcgatgc caagctgcaa cgcatcatgg attacgttac tagtgccgag
    15721 cgtgctgacg aaaatcaggc cattcgctta cccggccatg aatttactac cctgctggcc
    15781 gaaaaccgcc gtaacggcat cactgttgat gacagcgtgt gggccaaaat ccaggcgtta
    15841 tgaggagata agtcatgatt tttggacata tcgcgcagcc caatccgtgc cgtttgcccg
    15901 ccgccattga aaaggcgctc gattttctgc gcgctaccga tttcaacgcc ctggagccgg
    15961 gcgttgtcga aatcgacggc aaaaatattt atacgcaaat tatcgattta accacacgcg
    16021 aagcggtggt aaaccgtccg gaagtgcatc gtcggtatat cgatattcag tttctggcgt
    16081 ggggcgaaga gaaaatcggc attgctattg atacgggaaa taataaagtc agcgaatcac
    16141 tattagagca gcgcaatatt attttttatc acgacagtga acatgaatca tttatagaaa
    16201 tgataccggg cagctacgca attttctttc cgcaggatgt tcaccgacca ggttgtatta
    16261 tgcaaacagc ctctgagata cgaaaaattg tggttaaagt cgcattaacg gcgctgaatt
    16321 aatcgaataa tcgtctacgc cagaacgcct gggtaatgtt attgctctaa ctatattaat
    16381 aattcaggtt gctgcacatg cgacttgaat tatgacagac atagcctcaa ggaatagcta
    16441 tgaaaaaaat actcgaagca atactggcga ttaatctcgc cgtactttcc tgtattgtat
    16501 ttataaacat tattttaaga tatggttttc agacaagcat tttatctgtt gatgaattgt
    16561 cacgttattt atttgtctgg ttaacgttta ttggcgcgat tgtagctttt atggataacg
    16621 cccacgttca ggtcaccttt ctggtggaga aactctcccc cgcatggcag cgacgagtcg
    16681 ctctggttac ccattcctta atcttattta tttgtggcgc actggcctgg ggcgcaacgc
    16741 taaaaacaat tcaggactgg agcgattatt caccgatcct cggtttaccc atcggcctga
    16801 tgtatgccgc ttgtctgccc accagcctcg ttatcgcatt ctttgaactg cgtcatttat
    16861 atcaactcat cacgcgtagc aattctctaa cgtcgccacc gcaaggagct taatcatggc
    16921 tgtgctgatt tttctgggct gtctgttggg tggtattgct atcggtttgc ctattgcctg
    16981 ggcactgttg ttgtgcgggg cggcgttaat gttctggctg gacatgtttg atgtccagat
    17041 catggcacaa acgctggtga acggagccga tagcttctcc ctgctggcga ttccgttctt
    17101 tgtgctggcg ggtgaaatca tgaatgcggg cggcttgtca aaacgcattg ttgacctgcc
    17161 gatgaaactg gtggggcata aaccaggcgg gctgggctac gtcggcgtgc tggcagctat
    17221 gattatggcg agcctttctg gttctgccgt tgcggatacc gccgccgttg ccgctctact
    17281 ggtgccgatg atgcgcagcg ccaactatcc ggtcaaccgg gcggcggggc tgattgcctc
    17341 tggcggcatt atcgcgccaa ttattccccc ttccattccg tttattatct tcggcgtttc
    17401 cagcggatta tccatcagta agctgtttat ggcgggcatt gcccctggca tgatgatggg
    17461 cgcaacgctg atgcttacct ggtggtggca ggccagtcgc cttaatttac cccgccagca
    17521 aaaagcaacg atgcaggaaa tctggcactc ttttgtctcc ggtatctggg cgctgtttct
    17581 tccagtcatc attattggcg ggtttcgctc cggtctgttt acccctaccg aagccggggc
    17641 cgttgctgct ttctatgcgc tgtttgtcgc cacagttatt taccgtgaaa tgaccttcgc
    17701 cacactttgg catgtactca ttggcgcggc gaaaaccacc tcagtggtta tgtttctggt
    17761 ggcctcggca caagtttccg cctggctgat taccattgct gaactgccga tgatggtttc
    17821 tgatttactg caaccgttgg tcgattcacc gcgtctgctg tttatcgtca ttatggtggc
    17881 tatcctgatt gtcggcatgg tcatggattt aacgccgacg gtattaattc ttaccccggt
    17941 attaatgcct ttagttaaag aggcaggaat cgatccgatt tatttcggtg tcatgtttat
    18001 cattaactgc tcaatcggct taattacacc gcctatcggt aatgtactta acgttatttc
    18061 aggggtggca aaactcaaat tcgatgatgc agtcagaggc gttttccctt acgtcctggt
    18121 tttatattca ttattagtcg tatttgtttt tattcccgat ctcatcatcc tccctttgaa
    18181 atggattaat taaaaggaaa atattatgaa attacgctct gtaacctacg cattattcat
    18241 tgctggcctg gctgcattca gcacatcttc tctggcggca caatctttac gtttcggtta
    18301 tgaaacatca caaaccgact cgcaacatat tgcggcgaaa aaattcaatg atttattgca
    18361 ggagagaacc aaaggcgagc tgaaattaaa actgttcccg gacagcactc tcggtaacgc
    18421 gcaggcgatg atcagcggcg tacgtggcgg caccatcgat atggaaatgt ccggctcgaa
    18481 taactttgcc gggttatcac cagtgatgaa cttgcttgat gtccctttcc tgttccgcga
    18541 taccgctcac gcgcataaaa cgctcgacgg caaagtcggt gatgatctga aagcctcact
    18601 tgaaggtaaa ggactgaaag tactggccta ctgggaaaac ggctggcgcg atgtcaccaa
    18661 ctcgcgcgca ccggttaaaa cccccgccga cctgaaaggg ctgaaaatcc gcaccaacaa
    18721 tagcccgatg aatatcgccg cattcaaagt ctttggcgct aacccgatcc cgatgccgtt
    18781 tgccgaagtc tataccgggc tggaaacccg cactatcgac gctcaggaac acccgatcaa
    18841 cgtcgtctgg tcagcaaaat ttttcgaagt gcagaagttc ctttctctga cgcaccacgc
    18901 ctattccccg cttctggtgg tgatcaacaa agcgaagttt gatggcttaa gtccggagtt
    18961 ccagcaggcg ctagtttcat ctgcacaaga agcgggtaac tatcagcgca aactggttgc
    19021 tgaagatcag caaaaaatca tcgacggcat gaaagaagcg ggcgtggaag tcatcaccga
    19081 tctcgaccgc aaagccttta gcgacgcact ggggaatcag gttcgcgaca tgtttgttaa
    19141 agatgtgccg cagggagctg atctgctgaa agccgtggat gaggtgcaat aaaccatgac
    19201 gcaatactgg ctggggttag attgtggcgg tagctggctg aaagccgggc tgtatgaccg
    19261 cgaaggccgg gaggcaggcg tgcagcgcct gccgctgtgc gcattaagcc cgcagccagg
    19321 ctgggcagag cgcgatatgg cagaactgtg gcaatgctgc atggctgtca ttcgcgccct
    19381 gcttactcat tctggtgtta gcggggaaca aattgtcggt atcggcatct ccgcacaggg
    19441 aaagggcttg tttttgctgg ataaaaacga caaaccgctc gggaatgcta ttttgtcctc
    19501 ggaccgccgg gcgatggaaa tcgttcgtcg ctggcaggaa gatggcatcc cggaaaaact
    19561 ctacccgctg acccgacaaa ccttgtggac cgggcatccg gtgtcgctgt tacgctggct
    19621 gaaagagcac gaaccagaac gctacgcgca aattggctgc gtgatgatga cgcacgacta
    19681 cctgcgctgg tgtttaactg gcgtcaaagg ctgtgaagag agcaatattt ccgagtccaa
    19741 cctctacaac atgagtcttg gggaatatga cccgtgcctc accgactggc tggggatcgc
    19801 tgaaatcaat cacgccctgc cgcctgttgt cggatctgcc gaaatctgcg gggagatcac
    19861 cgctcagaca gccgccctga ccggtctgaa agcgggtacg cccgttgttg gcggcctgtt
    19921 tgatgtggtt tccaccgcac tctgcgccgg gatcgaagac gaatttaccc tcaatgcggt
    19981 gatggggacc tgggcggtga ccagcggcat aacccgcggt ttacgtgacg gtgaagcgca
    20041 tccgtatgtc tatggtcgct acgttaacga tggtgaattt atcgttcacg aagccagccc
    20101 tacctcttcc ggcaacctcg aatggtttac cgcacagtgg ggagaaatct cgtttgatga
    20161 gatcaatcag gccgttgcca gcttgccgaa ggctgggggc gatctctttt tcctgccgtt
    20221 cctgtacggc agcaacgccg gactcgagat gaccagtggt ttctacggga tgcaggccat
    20281 tcacacccgc gcgcacctgt tgcaggccat ctatgaaggg gtggtgttca gccatatgac
    20341 ccacctcaac cgaatgcgcg aacgttttac tgatgttcac accctacgcg tcactggcgg
    20401 cccggcgcac tccgatgtct ggatgcaaat gctggcggac gtcagcggtc tgcgtatcga
    20461 gctgccgcag gtggaagaaa ccggctgctt tggtgcggcc cttgccgccc gcgtcggcac
    20521 cggggtttat cacaacttca gcgaagccca acgtgacttg cgacacccgg tgcgcaccct
    20581 gctgccagat atgaccgccc atcagcttta ccaaaaaaaa tatcaacgtt atcagcatct
    20641 cattgccgca cttcagggct ttcacgcccg cattaaggag cacacattat gagccgacca
    20701 cttctgcaac tggccctcga ccactcatca cttgaagccg cgcagcgcga cgtgacgctg
    20761 ttaaaagaca gcgtcgatat cgtcgaagcg ggcaccattc tctgtttaaa cgaagggctt
    20821 ggcgcggtga aagccttgcg cgaacagtgc ccggacaaaa tcatcgttgc tgactggaag
    20881 gtcgccgacg ctggtgaaac gctcgcgcaa caggcgtttg gcgcaggcgc taactggatg
    20941 accatcatct gcgccgcgcc gctcgcgacg gtagaaaaag gccacgcaat ggcacaacgc
    21001 tgcgggggtg aaattcagat agagctgttc ggtaactgga cgctggacga cgcccgcgac
    21061 tggcatcgta ttggcgtgcg gcaggccatt tatcatcgcg gtcgtgatgc acaggccagc
    21121 gggcaacagt ggggcgaagc cgatctggca cgcatgaagg cgctttcaga tatcggcctt
    21181 gagctttcca ttactggcgg gattacccct gctgacctgc cgctgtttaa agatatccgc
    21241 gtgaaagcgt ttattgccgg gcgggcactg gcaggcgcgg caaatccggc gcaagtggct
    21301 ggcgatttcc atgcgcaaat cgacgctatc tggggaggtg cgcgtgcgta atcatccgtt
    21361 agggatttat gaaaaagcgc tggcgaaaga tctctcctgg ccggagcggc tggtgctggc
    21421 aaaaagctgc ggttttgatt ttgtcgaaat gtcggtggat gaaaccgacg aacggctctc
    21481 acgtcttgac tggagcgccg cacaaaggac ttcgctggtt gccgcgatga tcgaaacagg
    21541 tgttgggatc ccgtcgatgt gcctgtccgc acatcgtcgc tttccctttg gtagccgtga
    21601 cgaggcagtg cgcgaacggg cgcgggaaat catgagtaaa gcgattcgcc tggcgcgcga
    21661 tctcggcatt cgcaccatcc agctggcagg ttatgacgtc tattacgaag accacgacga
    21721 aggcacccgg caacgttttg ctgaagggct ggcgtgggca gtcgaacagg cggcggcatc
    21781 acaagtaatg ctggcggtgg agattatgga taccgcgttt atgaactcca tcagcaaatg
    21841 gaaaaaatgg gacgagatgc tcgcctcacc gtggttcacc gtctacccgg acgtcggcaa
    21901 cctcagcgcc tggggcaatg atgttcccgc cgaactgaaa ctgggcattg accgtatcgc
    21961 cgcgatccac ctgaaagaca cccagccagt caccgggcaa agtcccggac agttccgcga
    22021 cgtgccgttt ggcgaaggct gcgtcgattt cgttggcatc ttcaaaacgc tgcataaact
    22081 gaactatcgc ggttctttcc tgattgagat gtggaccgaa aaagccaaag agccggtgct
    22141 ggagattatt caggcgcggc gttggattga agcgcgtatg caggaggctg gatttatatg
    22201 ttagagcaac tgaaagccga cgtgctggcg gcgaatctgg cgcttcccgc tcaccatctg
    22261 gtgacgttca cctggggcaa tgtcagcgcg gtagacgaaa cgcggcaatg gatggtaatc
    22321 aaaccttccg gcgtcgagta cgacgtgatg accgccgacg atatggtggt ggttgagata
    22381 gccagcggta aggtggtgga aggcagcaaa aaaccctctt ccgatacacc aacgcatctg
    22441 gcgctctacc gtcgctatgc cgaaattggc ggtattgtgc atacccactc gcgccacgcc
    22501 accatctggt cacaggccgg gctggatctc cccgcctggg gcaccaccca cgccgattat
    22561 ttttacggtg ccatcccctg cacgcgacag atgaccgcag aggagattaa cggcgaatat
    22621 gaatatcaga ccggcgaagt gatcattgaa accttcgaag aacgtggcag gagtccggca
    22681 caaatcccgg cggtgctggt gcattctcac ggcccgttcg catggggtaa aaacgccgcc
    22741 gatgccgtgc ataacgccgt agtactcgaa gaatgcgcct atatgggtct attctcgcgc
    22801 cagcttgcgc cgcagctccc tgcgatgcaa aacgaactgc tggataagca ctacctgcgt
    22861 aagcatgggg ccaatgccta ttacgggcag taatccctca cgccggggct tcatcgcccc
    22921 ggcactacga attgatatgt tccttgctgt aacgccgctt ccacgctgct ggcgttaaac
    22981 cagtatgttt ctgaaaaatc tgccggaaat agccaacgtc attaaaccgt attgcatgga
    23041 gcaggccgac aacgtcgagt cactgcataa cctgttgctg cccgccgatg cgccatttac
    23101 gacatttgaa ggcaagggat tgttcagcca taagatcctg attcagacgc caggttcccg
    23161 gtatgaacag agcaatccag agcaacaacc tttgtggcat tacgacggag caccagccgc
    23221 accgacatct accggtgaat taaaaacgcc agctcacccc ggtgacaaag gtaaaactct
    23281 cattacgatc aatcatcggg ctgtcggtaa tctcttccgg cagctcgctg tatcctgcgc
    23341 tcgccatcaa tacgacgtgc tctcctatcg ggtattttgc cgtcaggctg acatagggca
    23401 cccaggcatc ctgcgcggaa taacttgcca gaccgctacg acgggactca ctctctgaaa
    23461 tgccatagta atagtcactg aaattctcgt cataatagag aacgcccagc gcaggtgtca
    23521 gcgacagacg acctatctgc attttgtgga ataccgatag ctcccccacc cagccgttgc
    23581 tgttatccag aacgtccgca gctgcagagg ctttcacggt tccccaacgc tcgtggtgat
    23641 accaggcaac ccccgccata gccgtactat cacgcttatc aagctgttgc atggcataat
    23701 cgtcattatc ggtagggtca aattccagcg gcatccagga tgcggtcagg ctaagttcat
    23761 ttttttcact ttgcgacaga ataaaaccta acgtggtctg acgaacataa aaagtatcac
    23821 cttcataact aatcagcgga attgccttcg tattttcatt ataaccgcga taaggcgatt
    23881 cattataagc cgcaccagca ccaatggata attcagaagc agttgcgctt gccataaaag
    23941 gcaacgaaaa taacgccaca atattgcgat taattaacat gtccggtatt ccattttaaa
    24001 ataagataaa aaagagtcgg cataataatg cttacaattt ctccggtgca agattcatat
    24061 ttatatagta atatataaaa ttatatataa ttgggctgtt gcgatgacaa aattacaact
    24121 taagtaccgg gagttaaaaa ttatctcggt aatcgctgcc agtgaaaata tcagccatgc
    24181 cgcgactgta cttggcatcg cacaggccaa cgtcagcaaa tatcttgctg attttgaatc
    24241 aaaagtgggt ttaaaagtct ttgaccgaac cacccggcag ctgatgctca caccttttgg
    24301 caccgcgctg ttaccgtaca tcaacgacat gctggacaga aacgagcaac ttaataattt
    24361 tattgcagat tataagcatg agaaacgtgg tcgggtcacc atctacgccc caaccggcat
    24421 aattacctat ttatccaaac atgtaatcga taaaattaaa gatatcggtg atatcacctt
    24481 atcgctaaaa acctgcaatc ttgagcgtaa tgccttttat gaaggcgtcg aatttcctga
    24541 tgattgtgat gttttaatca gctacgctcc accaaaagat gaatcgctgg ttgccagttt
    24601 tattacccaa tatgccgtaa ccgcttatgc cagccagcgc tatcttgaga aacatcccat
    24661 tagccgtcct gacgaactcg aacatcactc ctgtattttg atcgactcga tgatgatcga
    24721 cgacgcgaat atctggcgct tcaacgtcgc cgggagtaaa gaggtgcggg attatcgcgt
    24781 gaagggaaat tacgtttgcg acaacacgca atctgcgctg gagctggcac gaaatcacct
    24841 ggggattgtg tttgcgccag acaaaagtgt gcagagcgac ctgcaagacg gcacgctggt
    24901 gccctgcttt cagcaaccct atgaatggtg gctggatctg gtggctatct tccgtaaacg
    24961 ggaataccag ccctggcggg tccagtatgt gctggatgaa atgctgcgtg aaattcgcca
    25021 ccagcttgct cagtcgcagc aactgcggcc tgaacaagcg gcggaaagcg aagattaatg
    25081 atcgagataa aggtaatgca cccagctggt catgcgtaat agcactttgc gcatcaccga
    25141 gacatggctg aaatgatcag agtaaaccgc cacctgggcg taaataccgt ctggtaaagc
    25201 gctcaaatca gtgtgctcat ccagttcaat ggtcgcgata acgccatctg aacccggcgc
    25261 tgtgtttaac gtctgtaagg tgccggtcga ctgataagct ccgccgggaa cggctggact
    25321 aatggctgcc agcttaccgc tgaatacctt acctggcaga gcattaaaca ccacttccgc
    25381 atcgtcgcca ggagccagtc gcagcaagga gttctgacgg aactgcgcca cgatttgtcg
    25441 tttctgatcg ggtataaaca ccatcaccgg acgtagcggc agcgacgcgg cataggtacc
    25501 cggacgaatc agtacctggg tcacataacc atcgctcggc gcacgcacta tcgtctgctc
    25561 aaggttatat tttgcttccg cgagctgtgc tttcaggctg gcgatttgag aatgttcacc
    25621 caacaccagg ctatccagct ggctctggat ctgtttttgt tccgccgccg atgacttcac
    25681 ggaggcttcc tgcgccagat aattttgccg cgccacatcg atatcgcgtt ctgaaaacgg
    25741 gtttactttc gcctggctgc cacgtgcgta acgctgatac tctttagcga atttatcccg
    25801 cgtggccttt gcctgctgag tattcgccgc catctcatct aactctgcgc ccaacgcccg
    25861 ctgtttatgt tctgcggtaa cgatatccgc catcagccga tccacccgcg cctgataacg
    25921 cgtcgggtcc agtcgaaata gcacctcacc ttttttaatc agcgtatttt tcttatccgt
    25981 cacttcaatc accacaccag tcacctgtgg gacaacagga atagaaataa ccgctttttg
    26041 cgctttaaag gtatacggat ggttatagtt cattaacaga attagaccgc tgacaataaa
    26101 tattccaccc agggccgctg tgggaatggt ccatttattt acgggaattt tgaagatctt
    26161 aaacattgcc catgcaaaag ccacataggt caaaataatc agtaaatcca taagtattac
    26221 tcggcagaag aggatttgat gtcggcgagc tgtttctcca gcccggcaat gcgctgttgc
    26281 agttgcataa cggatgaatc atggctttgc attccccatc cccgctccgg gcggtaaagc
    26341 gtggcccaaa tccacaaaaa cggccagata acatgtaacg taaaaagact cacccaacca
    26401 gcaacatgaa tggcgtcggc atgaggatga ttacgttttt tggcaatcag gtagggaata
    26461 tcatgtaaaa taatgatccc atagaagatc accagaaata caaaaataag cactcccagt
    26521 gcaaaatagt ccaggaacat atttccctca aagaatataa aaaagaacaa ttaacgcata
    26581 ttatgaaatg ccatgatgca gtgcaatttc cttatttata taacgacata ttgtttttta
    26641 tatactttct taaatgtgct gtctggtttt tcaacaggac gaggtttatc atattgaaat
    26701 agtggaacta ttggccaaac taatgaataa ctccagtaaa acatccacag tacagattaa
    26761 gcgtattaaa ccttcaatta tctaccgttt attgctgatt ggcctcggat caccaatggt
    26821 gatttacggc ctggttcgcc cgctcaccat cgaaacgcga gattaaactc ctgacaaaac
    26881 acgccccaga aacgtacttc tgttggcgta gtctgggtta ttgcgcacgt aggtttaaaa
    26941 cgtaaattgt aacaacgtgc gctttgttta tgccggatgc ggcgtgtacg ccttatccgg
    27001 cctacggtca ggttcccgta ggcatgataa gacgcgtaag cgtcgcatca ggcaatgaat
    27061 acccaatgcg accagcttct tatatcagaa cagccccaac ggtttatccg agtagctcac
    27121 cagcaggcac ttggtttgct ggtaatgctc cagcatcatc ttgtgggttt cgcgaccgat
    27181 acctgattgt ttgtagccac caaacgccgc atgtgccggg taagcgtgat aacagttggt
    27241 ccacacgcac ccagcctgta tgccgcgccc catcttatag gccagattac cgttgcggct
    27301 ccagacgccc gcgcccaggc catattgcgt atcgttcgcc agctccagcg cttcttccat
    27361 cgttttgaag gtggtcaccg ccagcaccgg gccaaaaatc tcctcctgga acacccgcat
    27421 attgttctga ccaaacagaa tcgtcggttc gaggtagtag ccgtctttca gttcaccttc
    27481 cagcagcttg cgccgcccgc ctgtgagcac gtcagcgccc tcttttttac cgatatcaat
    27541 gtagttgagg atggtttcca gttgcccgtg agaaacctgc gcgcccattt gcgtcacgct
    27601 gtcgagcggg ttaccgctac gaatgctttc gacacggcgg atggcgcgtt ccataaagcg
    27661 ttcgtagata gattcctgca ctaaagcacg actcggacag gtgcaaactt cgccctggtt
    27721 aaaggcaaac agtgcaaagc cttccagcgc tttatcgaaa aaggcatctt cttcatccat
    27781 cacatcagca aagaagatat ttggcgactt accgcccaac tccagcgtca ccggaataat
    27841 gttttgcgtt gcgtattgca taatttgttg gcccacttcc gttgagccgg taaacgccac
    27901 tttggcgatg cgtttcgagg tcgccagata ttcgccaatt accccacctg cgccattgac
    27961 cacgttcacc acgcccggcg gcagtaaatc accgacaatt tccattagca gcagtacaga
    28021 aagcggggta agacgtgcgg gtttcagcac cacacagttg cccgccgcca gcgcgggagc
    28081 cattttccag ctcgccatca gcagcgggaa gttccacggg ataatctgcc ccaccacgcc
    28141 taacggttca tggaaatgat aggccacggt ttcgctatca acttcactga tcccaccttc
    28201 ctgcgcccga atacacgagg cgaaatagcg gaaatggtca atcgccagcg gtacatccgc
    28261 agcactggtt tcgcgaatgg gtttgccgtt atcccaggtt tcagctgtcg ctaacagctc
    28321 gaggttttgt tccattcgat cggcaatctt aaacagaatc gccgcacgat cctgcaccga
    28381 ggtgtgcgcc catttatctt tcactttgtg cgcagcatcc agcgccagat cgatgtctcg
    28441 tttgcccgaa gacgccactt cgcacagcag ctgcccggtc accggcgtca gattctggta
    28501 atactcgccg tcggcagggg ctacccattc gccgccaata aagttgtcat agcgggcttt
    28561 taacttgagg gggaaaccat actcgccggg cttaatctgt gctgaagggg gattattggt
    28621 catgatcgtc tccttgcggt gtgaggtata acaagggtag acgtgactgg cgaaatcttc
    28681 gccagtcggt aacagcttta cgacagctat cacgaattta cgggcaaggg ttacagagat
    28741 agttgaaaaa gcggctgaca atttgccagc cgttgtggaa atgatgatta catcgctgcg
    28801 cgataaatcg ccacaatttc ttcgtgagtt gcctggatcg ggttagtaaa gccacaggca
    28861 tctttcaggg cattagtcgc caataccgcg aaatcttctt ctttcacgtt caggtcgcgt
    28921 aggcctgccg ggatatccac tttcttcgcc agttcacgga tggcgttaat gcaggcttca
    28981 gcaccttccg cgtcgttttt acctgtcacg ttcacgccca ttgcagcggc acagtcacgc
    29041 agacgtgcag cggcgacttt gctgttgaat acctgaacgt gcggcagcaa aacggcgtta
    29101 catacaccgt gtggcaggtt gtagaaaccg cccagctggt gcgccatcgc atgaacataa
    29161 cccagagaag cattattgaa cgccataccg gcgaggaact gggcataagc cattgcttca
    29221 cgcgctttcg cattactgcc atcttcaacg gctaacggca ggttttcggc aatcatggtc
    29281 acggctttca gtgcacaagc gtcagtgatc ggcgtggcgg caatagaaac atatgcttcg
    29341 atagcgtgcg ttaaggcatc catacccgtt gcggcggtca gtgacttcgg cataccaatc
    29401 atcagagagg agtcattgac agaaagcagc ggagtgacat gtttatcaac aatcgccatt
    29461 ttgatatgac gcgcttcgtc agtgatgatg cagaaacggg tcatttcaga ggccgtaccc
    29521 gccgtggtat tgatggcgat catcggcagc tgcggttttg cagagcggtc aacgccttcg
    29581 taatcgcgaa tatcgccgcc attggctgcc accagcgcaa taccttttgc gcagtcgtgt
    29641 ggagaaccac cgcctaagga gatcacgcta tcgcaattat tctctttaag taatttcaaa
    29701 cctgcggcga cgttttccgt ggtggggtta ggttgggtgc catcataaat aacgctaaaa
    29761 atattgcgtt cttccagtgc tttttgcaca tcgcccgcca tacctaattt cgttaacata
    29821 ttgtcagtga caattaaggt acgggtaaat ccataatctg ccatcatatt cattgcatca
    29881 gtcaatgaat cagcgccgat gacattcaca gaaggaataa agaacgttga agctgccata
    29941 acacactcct gaaagtgtaa aaaagggcgg gcagcttact gaggattgtc attcgaaaat
    30001 atgatcagta ttattgatta tcaaaattaa tctaataaaa
//
LOCUS       DAPOAV010000053        29120 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.053, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000053 DAPOAV010000000
VERSION     DAPOAV010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 29120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29120
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.053"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            204..1481
                     /gene="waaA"
                     /locus_tag="RN951_002677"
     CDS             204..1481
                     /gene="waaA"
                     /locus_tag="RN951_002677"
                     /EC_number="2.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) 3-deoxy-D-manno-octulosonic acid
                     transferase"
                     /protein_id="HDX2527656.1"
                     /translation="MLELLYTALLYLIQPLIWIRLWVRGRKAPAYRKRWGERYGFYRH
                     PLKPGGIMLHSVSVGETLAAIPLVRALRHRYPDLPITVTTMTPTGSERVQSAFGKDVQ
                     HVYLPYDLPDALNRFLNKVDPKLVLIMETELWPNLIAALHKRKIPLVIANARLSARSA
                     AGYAKLGKFVRRLLRRITLIAAQNEEDGARFVALGAKNNQVTVTGSLKFDISVTPQLA
                     AKAVTLRRQWAPHRPVWIATSTHEGEESVVIAAHQALLQQFPNLLLILVPRHPERFPD
                     AINLVRQAGLSYITRSSGEVPSTSTQVVVGDTMGELMLLYGIADLAFVGGSLVERGGH
                     NPLEAAAHAIPVLMGPHTFNFKDICARLEQASGLITVTDATTLVKEVSSLLTDADYRS
                     FYGRHAVEVLYQNQGALQRLLQLLEPYLPPKTH"
     gene            1489..1968
                     /gene="coaD"
                     /locus_tag="RN951_002678"
     CDS             1489..1968
                     /gene="coaD"
                     /locus_tag="RN951_002678"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HDX2527657.1"
                     /translation="MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKP
                     MFTLEERVELAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQL
                     AHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA"
     gene            complement(2007..2816)
                     /gene="mutM"
                     /locus_tag="RN951_002679"
     CDS             complement(2007..2816)
                     /gene="mutM"
                     /locus_tag="RN951_002679"
                     /EC_number="3.2.2.23"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-formamidopyrimidine
                     glycosylase/DNA-(apurinic or apyrimidinic site) lyase"
                     /protein_id="HDX2527658.1"
                     /translation="MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRL
                     SDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMNNGKV
                     LRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMD
                     NKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLK
                     DFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK"
     gene            complement(2914..3081)
                     /gene="rpmG"
                     /locus_tag="RN951_002680"
     CDS             complement(2914..3081)
                     /gene="rpmG"
                     /locus_tag="RN951_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010847629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDX2527659.1"
                     /translation="MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVR
                     QHVIYKEAKIK"
     gene            complement(3102..3338)
                     /gene="rpmB"
                     /locus_tag="RN951_002681"
     CDS             complement(3102..3338)
                     /gene="rpmB"
                     /locus_tag="RN951_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008457442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HDX2527660.1"
                     /translation="MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEK
                     RFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY"
     gene            complement(3555..4223)
                     /gene="radC"
                     /locus_tag="RN951_002682"
     CDS             complement(3555..4223)
                     /gene="radC"
                     /locus_tag="RN951_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418095.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDX2527661.1"
                     /translation="MKNNSQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTL
                     AKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQLKGIAELARRYYNVRMREESPLL
                     SPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHCRLFSGTLNHVEVHPREIIREAI
                     KINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAE
                     RGWI"
     gene            4395..5615
                     /gene="coaBC"
                     /locus_tag="RN951_002683"
     CDS             4395..5615
                     /gene="coaBC"
                     /locus_tag="RN951_002683"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418096.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HDX2527662.1"
                     /translation="MSLAGKKIVLGVSGGIAAYKTPELVRRLRDRGADVRVAMTEAAK
                     AFITPLSLQAVSGYPVSDSLLDPAAEAAMGHIELGKWADLVILAPATADLIARVAAGM
                     ANDLVSTICLATPAPVAVLPAMNQQMYRAAATQHNLEVLASRGLLIWGPDSGSQACGD
                     IGPGRMLDPLTIVDMAVAHFSPVNDLKHLNIMITAGPTREPLDPVRYISNHSSGKMGF
                     AIAAAAARRGANVTLVSGPVSLPTPPFVKRVDVMTALEMEAAVNASVQQQNIFIGCAA
                     VADYRAATVAPEKIKKQATQGDELTIKMVKNPDIVAGVAALKDHRPYVVGFAAETNNV
                     EEYARQKRIRKNLDLICANDVSQPTQGFNSDNNALHLFWQDGDKVLPLERKELLGQLL
                     LDEIVTRYDEKNRR"
     gene            5593..6051
                     /gene="dut"
                     /locus_tag="RN951_002684"
     CDS             5593..6051
                     /gene="dut"
                     /locus_tag="RN951_002684"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HDX2527663.1"
                     /translation="MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLDDAVELA
                     PGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVW
                     NRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ"
     gene            6158..6754
                     /gene="slmA"
                     /locus_tag="RN951_002685"
     CDS             6158..6754
                     /gene="slmA"
                     /locus_tag="RN951_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion factor SlmA"
                     /protein_id="HDX2527664.1"
                     /translation="MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVS
                     EAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTTARLRLIVLLLLGFGERN
                     PGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDETLLAS
                     QILAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ"
     gene            complement(6791..7432)
                     /gene="pyrE"
                     /locus_tag="RN951_002686"
     CDS             complement(6791..7432)
                     /gene="pyrE"
                     /locus_tag="RN951_002686"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HDX2527665.1"
                     /translation="MKPYQRQFIEFALSKQVLKFGEFTLKSGRKSPYFFNAGLFNTGR
                     DLALLGRFYAEALVDSGIEFDLLFGPAYKGIPIATTTAVALAEHHDLDLPYCFNRKEA
                     KDHGEGGNLVGSALQGRVMLVDDVITAGTAIRESMEIIQANGATLAGVLISLDRQERG
                     RGEISAIQEVERDYNCKVISIITLKDLIAYLEEKPEMAEHLAAVKAYREEFGV"
     gene            complement(7497..8213)
                     /gene="rph"
                     /locus_tag="RN951_002687"
     CDS             complement(7497..8213)
                     /gene="rph"
                     /locus_tag="RN951_002687"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006803115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HDX2527666.1"
                     /translation="MRPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIE
                     EGVPRFLKGQGQGWITAEYGMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAV
                     DLKALGEFTITLDCDVLQADGGTRTASITGACVALADALQKLVENGKLKTNPMKGMVA
                     AVSVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLTLL
                     ALARGGIESIVATQKAALAN"
     gene            8340..9203
                     /locus_tag="RN951_002688"
     CDS             8340..9203
                     /locus_tag="RN951_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HDX2527667.1"
                     /translation="MIRSMTAYARREIKGEWGSATWEMRSVNQRYLETYFRLPEQFRS
                     LEPVVRERIRSRLTRGKVECTLRYEPDVSAQGELILNEKLAKQLVTAANWVKMQSDEG
                     EINPVDILRWPGVMAAQEQDLDAIAAEILAALDGTLDDFIVARETEGQALKALIEQRL
                     EGVTAEVVKVRSHMPEILQWQRERLVAKLEDAQVQLENNRLEQELVLLAQRIDVAEEL
                     DRLEAHVKETYNILKKKEAVGRRLDFMMQEFNRESNTLASKSINAEVTNSAIELKVLI
                     EQMREQIQNIE"
     gene            9425..10249
                     /gene="dinD"
                     /locus_tag="RN951_002689"
     CDS             9425..10249
                     /gene="dinD"
                     /locus_tag="RN951_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418102.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein D"
                     /protein_id="HDX2527668.1"
                     /translation="MNEHHQPFEEIKLINANGAEQWSARQLGKLLGYSEYRHFIPVLT
                     RAKEACENSGHTIDDHFEEILDMVKIGSNAKRALKDIVLSRYACYLVVQNGDPAKPVI
                     AAGQTYFAIQTRRQELADDEAFKQLREDEKRLFLRNELKEHNKQLVEAAQQAGVATAT
                     DFAIFQNHGYQGLYGGLDQKAIHQRKGLKKNQKILDHMGSTELAANLFRATQTEEKLK
                     RDGVNSKQQANTTHFDVGSKVMQTIQELGGTMPEELPTPQVSIKQLENSVKITEKK"
     gene            10541..11158
                     /locus_tag="RN951_002690"
     CDS             10541..11158
                     /locus_tag="RN951_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312548.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HDX2527669.1"
                     /translation="MLLHILYLVGITAEAMTGALAAGRRRMDTFGVIIIATATAIGGG
                     SVRDILLGHYPLGWVKHPEYVIIVATAAVLTTIVAPVMPYLRKVFLVLDALGLVVFSI
                     IGAQVALDMGHGPIIAVVAAVTTGVFGGVLRDMFCKRIPLVFQKELYAGVSFASAVLY
                     IALQHYVSNHDVVIISTLVFGFFARLLALRLKLGLPVFYYSHEGH"
     gene            complement(11155..12837)
                     /gene="ligB"
                     /locus_tag="RN951_002691"
     CDS             complement(11155..12837)
                     /gene="ligB"
                     /locus_tag="RN951_002691"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418104.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigB"
                     /protein_id="HDX2527670.1"
                     /translation="MKVWMAILISILCWQSSVWAVCPAWSPARAQEEISRLQQQIKQW
                     DDDYWKEGKSEVEDGVYDQLSARLTQWQRCFGSEPRDVMMPPLNGAVMHPVAHTGVRK
                     MVDKNALSLWMRERSDLWVQPKVDGVAVTLVYRDGKLNKAISRGNGLKGEDWTQKVSL
                     ISAVPQTVSGPLANSTLQGEIFLQREGHIQQQMGGINARAKVAGLMMRQDDSDTLNSL
                     GVFVWAWPDGPQLMSDRLKELATAGFTLTQTYTRAVKNADEVARVRNEWWKAELPFVT
                     DGVVVRAAKEPESRHWLPGQAEWLVAWKYQPVAQVAEVKAIQFAVGKSGKISVVASLA
                     PVMLDDKKVQRVNIGSVRRWQEWDIAPGDQILVSLAGQGIPRIDDVVWRGAERTKPTP
                     PENRFNSLTCYFASDVCQEQFISRLVWLGSKQVLGLDGIGEAGWRALHQTHRFEHIFS
                     WLLLTPEQLQNTPGIAKSKSAQLWHQFNLARKQPFTRWVMAMGIPLTRAALNASDERS
                     WSQLLFSTEQFWQQLPGTGSGRARQVIEWKENAQIKKLGSWLAAQQITGFEP"
     gene            13095..13718
                     /gene="gmk"
                     /locus_tag="RN951_002692"
     CDS             13095..13718
                     /gene="gmk"
                     /locus_tag="RN951_002692"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HDX2527671.1"
                     /translation="MAQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQP
                     RPGEVHGEHYFFVNHDEFKEMISRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLD
                     IDWQGAQQIRQKMPHARSIFILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEMSHY
                     AEYDYLIVNDDFDTALTDLKTIIRAERLRMSRQKQRHDALISKLLAD"
     gene            13773..14048
                     /gene="rpoZ"
                     /locus_tag="RN951_002693"
     CDS             13773..14048
                     /gene="rpoZ"
                     /locus_tag="RN951_002693"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013511051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HDX2527672.1"
                     /translation="MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEEND
                     KTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR"
     gene            14067..16175
                     /gene="spoT"
                     /locus_tag="RN951_002694"
     CDS             14067..16175
                     /gene="spoT"
                     /locus_tag="RN951_002694"
                     /EC_number="3.1.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional GTP
                     diphosphokinase/guanosine-3',5'-bis pyrophosphate
                     3'-pyrophosphohydrolase"
                     /protein_id="HDX2527673.1"
                     /translation="MYLFESLNQLIQTYLPEDQIKRLRQAYLVARDAHEGQTRSSGEP
                     YITHPVAVACILAEMKLDYETLMAALLHDVIEDTPATYQDMEQLFGKSVAELVEGVSK
                     LDKLKFRDKKEAQAENFRKMIMAMVQDIRVILIKLADRTHNMRTLGSLRPDKRRRIAR
                     ETLEIYSPLAHRLGIHHIKTELEELGFEALYPNRYRVIKEVVKAARGNRKEMIQKILS
                     EIEGRLQEAGIPCRVSGREKHLYSIYCKMVLKEQRFHSIMDIYAFRVIVNDSDTCYRV
                     LGQMHSLYKPRPGRVKDYIAIPKANGYQSLHTSMIGPHGVPVEVQIRTEDMDQMAEMG
                     VAAHWAYKEHGETSTTAQIRAQRWMQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFT
                     PEGRIVELPAGATPVDFAYAVHTDIGHACVGARVDRQPYPLSQPLTSGQTVEIITAPG
                     ARPNAAWLNFVVSSKARAKIRQLLKNLKRDDSVSLGRRLLNHALGGSRKLNEIPQENI
                     QRELDRMKLATLDDLLAEIGLGNAMSVVVAKNLQHGDASIPPATQSHGHLPIKGADGV
                     LITFAKCCRPIPGDPIIAHVSPGKGLVIHHESCRNIRGYQKEPEKFMAVEWDKETAQE
                     FITEIKVEMFNHQGALANLTAAINTTTSNIQSLNTEEKDGRVYSAFIRLTARDRVHLA
                     NIMRKIRVMPDVIKVTRNRN"
     gene            16182..16871
                     /gene="trmH"
                     /locus_tag="RN951_002695"
     CDS             16182..16871
                     /gene="trmH"
                     /locus_tag="RN951_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(18)-2'-O)-methyltransferase
                     TrmH"
                     /protein_id="HDX2527674.1"
                     /translation="MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVG
                     VHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNA
                     VDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYE
                     AQRQRQNAGMYLRENSMLPEAEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEAD
                     ADWWSTMQAAG"
     gene            16877..18958
                     /gene="recG"
                     /locus_tag="RN951_002696"
     CDS             16877..18958
                     /gene="recG"
                     /locus_tag="RN951_002696"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709432.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HDX2527675.1"
                     /translation="MKGRLLDTVPLSSLTGVGAALSNKLAKINLHTVQDLLLHLPLRY
                     EDRTHLYPIGELLPGVYATVEGEVLNCNISFGGRRMMTCQISDGSGILTMRFFNFSAA
                     MKNSLATGRRVLAYGEAKRGKYGAEMIHPEYRVQGDLSTPELQETLTPVYPTTEGVKQ
                     ATLRKLTDQALDLLDTCAIEELLPPELSQGMMTLPEALRTLHRPPPTLQLSDLETGQH
                     PAQRRLILEELLAHNLSMLALRAGAQRFHAQPLSANDTLKNKLLAALPFKPTGAQARV
                     VAEIEHDMALDVPMMRLVQGDVGSGKTLVAALAALRAIAHGKQVALMAPTELLAEQHA
                     NNFRNWFAPLGIKVGWLAGKQKGKARLSQQEAIASGQVQMIVGTHAIFQEQVQFNGLA
                     LVIIDEQHRFGVHQRLALWEKGQQQGFHPHQLIMTATPIPRTLAMTAYADLDTSVIDE
                     LPPGRTPVTTVAIPDTRRTDIIDRVRHACITEGRQAYWVCTLIEESELLEAQAAEATW
                     EELKLALPELNVGLVHGRMKPAEKQAVMASFKQGELHLLVATTVIEVGVDVPNASLMI
                     IENPERLGLAQLHQLRGRVGRGAVASHCVLLYKTPLSKTAQIRLQVLRDSNDGFVIAQ
                     KDLEIRGPGELLGTRQTGNAEFKVADLLRDQAMIPEVQRLARHIHERYPQQAKALIER
                     WMPETERYSNA"
     gene            complement(19124..20329)
                     /gene="gltS"
                     /locus_tag="RN951_002697"
     CDS             complement(19124..20329)
                     /gene="gltS"
                     /locus_tag="RN951_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HDX2527676.1"
                     /translation="MFHLDTLATLVAATLTLLLGRKLVHSVSFLKKYTIPEPVAGGLL
                     VALALLVLKKSMGWEVNFDMSLRDPLMLAFFATIGLNANIASLRAGGRVVGIFLIVVV
                     GLLVMQNAIGIGMASLLGLDPLMGLLAGSITLSGGHGTGAAWSKLFIERYGFTNATEV
                     AMACATFGLVLGGLIGGPVARYLVKHSTTPNGIPDDQEVPTAFEKPDVGRMITSLVLI
                     ETIALIAICLTVGKIVAQLLAGTAFELPTFVCVLFVGVILSNGLSIMGFYRVFERAVS
                     VLGNVSLSLFLAMALMGLKLWELASLALPMLAILVVQTIFMALYAIFVTWRMMGKNYD
                     AAVLAAGHCGFGLGATPTAIANMQAITERFGPSHMAFLVVPMVGAFFIDIVNALVIKL
                     YLMLPIFAG"
     gene            20609..22000
                     /gene="xanP"
                     /locus_tag="RN951_002698"
     CDS             20609..22000
                     /gene="xanP"
                     /locus_tag="RN951_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/proton symporter XanP"
                     /protein_id="HDX2527677.1"
                     /translation="MSVSTLESENAQPVAQTQNSELIYRLEDRPPLPQTLFAACQHLL
                     AMFVAVITPALLICQALGLPAQDTQHIISMSLFASGVASIIQIKAWGPVGSGLLSIQG
                     TSFNFVAPLIMGGTALKTGGADVPTMMAALFGTLMLASCTEMVISRVLHLARRIITPL
                     VSGVVVMIIGLSLIQVGLTSIGGGYAAMSDNTFGAPKNLLLAGVVLALIILLNRQRNP
                     YLRVASLVIAMAAGYALAWFMGMLPESNEPMTQELIMVPTPLYYGLGIEWSLLLPLML
                     VFMITSLETIGDITATSDVSEQPVSGPLYMKRLKGGVLANGLNSFVSAVFNTFPNSCF
                     GQNNGVIQLTGVASRYVGFVVALMLIVLGLFPAVSGFVQHIPEPVLGGATLVMFGTIA
                     ASGVRIVSREPLNRRAILIIALSLAVGLGVSQQPLILQFAPEWLKNLLSSGIAAGGIT
                     AIVLNLIFPPEKQ"
     gene            22121..23830
                     /locus_tag="RN951_002699"
     CDS             22121..23830
                     /locus_tag="RN951_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709435.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HDX2527678.1"
                     /translation="MKFIGKLLLYILIALLVVIAGLYFLLQTRWGAEHISAWVSENSD
                     YHLAFGAMDHRFSAPSHIVLENVTFGRDGQPATLVAKSVDIALSSRQLTEPRHVDTIL
                     LENGTLNLTDQTAPLPFKADRLQLRDMAFNSPNSEWKLSAQRVNGGVVPWSPEAGKVL
                     GTKAQIQFSAGSLSLNDVPATNVLIEGSIDNDRVTLTNLGADIARGTLTGNAQRNADG
                     SWQVENLRMADIRLQSEKSLTDFFAPLRSVPSLQIGRLEVIDARLQGPDWAVTDLDLS
                     LRNMTFSKDDWQTQEGKLSMNASEFIYGSLHLFDPIINAEFSPQGVALRQFTSRWEGG
                     MVRTSGNWLRDGKTLILDDAAIAGLEYTLPKNWQQLWMETTPGWLNSLQLKRFSASRN
                     LIIDIDPDFPWQLTTLDGYGANLTLVTDHKWGVWSGSANLNAAAATFNRVDVRRPSLA
                     LTANSSTVNISELSAFTEKGILEATASVSQTPQRQTHISLNGRGVPVNILQQWGWPEL
                     PLTGDGNIQLTASGDIQANAPLKPTVSGQLHAVNAAKQQVTQTMNAGIVSSGEVTSTE
                     PVR"
     gene            complement(23883..26201)
                     /gene="yicI"
                     /locus_tag="RN951_002700"
     CDS             complement(23883..26201)
                     /gene="yicI"
                     /locus_tag="RN951_002700"
                     /EC_number="3.2.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HDX2527679.1"
                     /translation="MKISDGNWLIQPGLNLIHPLQVFEVEQQDNEMVVYAAPRDVRER
                     TWQLDTPLFTLRFFSPQEGIVGVRIEHFQGALNNGPHYPLNILQDVKVTIENTERYAE
                     FKSGNLSARVSKGEFWSLDFLRNGERITGSQVKNNGYVQDTNNQRNYMFERLDLGVGE
                     TVYGLGERFTALVRNGQTVETWNRDGGTSTEQAYKNIPFYMTNRGYGVLVNHPQCVSF
                     EVGSEKVSKVQFSVESEYLEYFVIDGPTPKAVLDRYTRFTGRPALPPAWSFGLWLTTS
                     FTTNYDEATVNSFIDGMAERNLPLHVFHFDCFWMKAFQWCDFEWDPLTFPDPEGMIRR
                     LKAKGLKICVWINPYIGQKSPVFKELQEKGYLLKRPDGSLWQWDKWQPGLAIYDFTNP
                     DACKWYADKLKGLVAMGVDCFKTDFGERIPTDVQWFDGSDPQKMHNHYAYIYNELVWN
                     VLKDTVGEEEAVLFARSASVGAQKFPVHWGGDCYANYESMAESLRGGLSIGLSGFGFW
                     SHDIGGFENTAPAHVYKRWCAFGLLSSHSRLHGSKSYRVPWAYDDESCDVVRFFTQLK
                     CRMMPYLYREAARANARGTPMMRAMMMEFPDDPACDYLDRQYMLGDNVMVAPVFTEAG
                     DVQFYLPEGRWTHLWHNDELDGSRWHKQQHGFLSLPVYVRDNTLLALGNNDQRPDYVW
                     HEGTAFHLFNLQDGHEAVCEVPAADGSVIFTLKAARTGNTITVTGAGEAKNWTLCLRN
                     VVKVNGLQDGSQAESEQGLVVKPQGNALTITL"
     gene            complement(26211..27593)
                     /locus_tag="RN951_002701"
     CDS             complement(26211..27593)
                     /locus_tag="RN951_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418114.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide family
                     transporter"
                     /protein_id="HDX2527680.1"
                     /translation="MKSEVLSVKEKIGYGMGDAASHIIFDNVMLYMMFFYTDIFGIPA
                     GFVGTMFLVARALDAISDPCMGLLADRTRSRWGKFRPWVLFGALPFGIVCVLAYSTPD
                     LSMNGKMIYAAITYTLLTLLYTVVNIPYCALGGVITNDPTQRISLQSWRFVLATAGGM
                     LSTVLMMPLVNLIGGDNKPLGFQGGIAVLSVVAFMMLAFCFFTTKERVEAPPTTTSMR
                     EDLRDIWQNDQWRIVGLLTIFNILAVCVRGGAMMYYVTWILGTPEVFVAFLTTYCVGN
                     LIGSALAKPLTDWKCKVTIFWWTNALLAVISLAMFFVPMQASITMFVFIFVIGVLHQL
                     VTPIQWVMMSDTVDYGEWCNGKRLTGISFAGTLFVLKLGLAFGGALIGWMLAYGGYDA
                     AEKAQNSATISIIIALFTIVPAICYLLSAIIAKRYYSLTTHNLKTVMEQLAQGKRRCQ
                     QQFTSQEVQN"
     gene            27886..27980
                     /locus_tag="RN951_002702"
     tRNA            27886..27980
                     /locus_tag="RN951_002702"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:27920..27922,aa:Sec,seq:tca)
     gene            28617..>29120
                     /locus_tag="RN951_002703"
     CDS             28617..>29120
                     /locus_tag="RN951_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2527681.1"
                     /translation="MQKTATTPSKILDLTAAAFLLVAFLTGIAGALQTPTLSIFLADE
                     LKARPIMVGFFFTGSAIMGILVSQFLARHSDKQGDRKLLILLCCLFGVLACTLFAWNR
                     NYFILLSTGVLLSSFASTANPQMFALAREHADRTGRETVMFSTFLRAQISLAWVIGPP
                     LAYELAMG"
BASE COUNT         7132 a         7831 c         7284 g         6873 t
ORIGIN      
        1 tactcgagaa tccagatatt gtcgatgtaa agctgcaatc ctggctgaaa ttcaatgaat
       61 cgcataaaaa tacaaaaaaa atgaagatct agcggcagat cagctcaaac agaggctaat
      121 taagtcaaaa aaaggaaaag taatggcaaa cccggtgcta aatacataga atccccagca
      181 catccataag tcagctattt attatgcttg aattgcttta caccgccctt ctctacctta
      241 ttcagccgct gatctggata cggctctggg tgcgcggacg taaggctccg gcctatcgaa
      301 aacgctgggg tgaacgttac ggtttttacc gccatccgct aaaaccaggc ggcattatgc
      361 tgcactccgt ctccgtcggt gaaactctgg cggcgatccc attggtgcgc gcgctgcgtc
      421 atcgttatcc tgatttaccg attaccgtta caaccatgac accaaccggt tcggagcgcg
      481 tacaatcggc tttcgggaag gatgttcagc acgtttatct gccatatgac ctgcccgatg
      541 cacttaatcg tttcctgaat aaagtcgacc ctaaactggt gttgattatg gaaaccgaac
      601 tatggcctaa cctgattgcg gcgctacata aacgtaaaat tccgctggtg atcgctaacg
      661 cgcgactctc tgcccgctcg gccgcaggtt atgccaaact gggtaaattc gtccgtcgct
      721 tgctgcgtcg tattacgctg attgccgccc aaaatgaaga agatggtgca cgttttgtgg
      781 cgctgggcgc aaaaaataat caggtgaccg ttaccggtag cctgaaattc gatatttctg
      841 taacgccgca actggctgct aaagcagtga cgctgcgccg ccagtgggca ccacaccgcc
      901 cggtatggat tgccaccagc actcacgaag gtgaagagag cgtggtcatt gccgcacatc
      961 aggcattatt acagcaattc ccgaatttat tgctcatcct ggtaccccgt catccggaac
     1021 gcttcccgga tgcgattaac cttgtccgcc aggctggact aagctatatc acacgctctt
     1081 caggggaagt cccctccacc agcacgcagg ttgtggttgg cgatacgatg ggcgagttga
     1141 tgttactgta cggcattgcc gatctcgctt ttgttggcgg ttcactggtt gaacgtggtg
     1201 ggcataatcc gctggaagct gccgcacacg ctattccggt attgatgggg ccgcatactt
     1261 ttaactttaa agacatttgc gcgcggctgg agcaggcaag cgggctgatt accgttaccg
     1321 atgccactac gcttgtaaaa gaggtttcct ctttactcac cgacgccgat taccgtagtt
     1381 tctatggccg tcatgccgtt gaagtactgt atcaaaacca gggcgcgcta cagcgtctgc
     1441 ttcaactgct ggaaccttac ctgccaccga aaacgcattg aggttgttat gcaaaaacgg
     1501 gcgatttatc cgggtacttt cgatcccatt accaatggtc atatcgatat cgtgacgcgc
     1561 gccacgcaaa tgttcgatca cgttattctg gcgattgccg ccagccccag taaaaaaccg
     1621 atgtttaccc tggaagagcg tgtggagctg gcacagcagg caaccgcgca tctggggaac
     1681 gtggaagtgg tcgggtttag tgatttgatg gcgaacttcg cccgcaatca acacgctacg
     1741 gtgctgattc gtggcctgcg tgcggtggca gattttgaat atgaaatgca gctggcgcat
     1801 atgaatcgcc acttaatgcc ggaactggaa agtgtgtttc tgatgccgtc gaaagagtgg
     1861 tcgtttatct cttcatcgtt ggtgaaagag gtggcgcgcc atcagggcga tgtcacccat
     1921 ttcctgccgg agaatgtcca tcaggcgctg atggcgaagt tagcgtagcg tttatgccgg
     1981 atggtatgcc atccggcgcg catgaattac ttctggcact gccgacaata aaacgttgcc
     2041 cgctgcgcat gtttagtcgc cacaatcggc gtaccgcaca cccgacacgg ctcacctttt
     2101 cgcccgtaaa cctgcaattc ctgcgcgaaa tagcccggtt taccgtcgct ttgcagaaaa
     2161 tcttttagcg ttgtaccgcc ctgctcaatc gaacgcagca acaccgcttt aatcacccga
     2221 gccagcaatt cgcactccgc cagcgacagt gatgacgcca gccgatccgg atggatcccc
     2281 gccgcaaaca gagattcgct ggcatagata ttccctacgc ctaccaccag cttgttatcc
     2341 atcagccacg gtttgatcgc cgtttttttc ttcgcgcact tctgatgcag atactcacca
     2401 ttgaaatcgt cgctaagcgg ctccggtcca agatgggcca gcacattatg cccttccagc
     2461 tctttggtcc acagccaggc accaaagcgg cgcggatcgg tgtagcgcag cactttgccg
     2521 ttgttcatca ccaaatccac atggtcatgc ttttcagggg gaagttcttc tggaaggatg
     2581 cgcaggctgc cagacatccc taaatgaatg ataatccagc cctcaggcag ctccagcagc
     2641 agatatttag cccgccgctg cacgctaagc actggttggt cgcttaaacg gtagatctct
     2701 tctgaaaccg gccagcgcaa gcgtccgttg cgcaccactg catgaagaat ggttgcacca
     2761 acgagatgcg gttctatgcc gcggcggctg gtttcaactt cgggtaattc aggcatagca
     2821 tctccaggaa tgaacagatg cagtcaatat gggggcaagc agataacaaa aaaccccgcc
     2881 ggagcgaggt tttttgttac atcaaagcga gaattatttg attttcgctt ctttgtagat
     2941 cacgtgctgg cgaacaactg gatcgaattt tttcagttcc agtttttccg gcttagtacg
     3001 tttgttcttc gtagtggtat agaagtgacc agtaccagca gaagaaacca gcttgatttt
     3061 ctcacgaata cctttagcca tgatttattt cctctaagta cttagtactt ttcgccacgg
     3121 gcacgcagtt cagccagaac tgtatcgatg ccttttttat cgattacacg cataccttta
     3181 gcagatacgc gcagggtgac aaaacgcttc tcgctctcaa cccagaaacg gtgagagtgc
     3241 aggttcggca ggaaacggcg tttagtcgcg ttcagtgcgt gggaacggtt gttaccggtc
     3301 accggacgct tgccagtaac ttggcagact cgggacatgt ctattctcca aaaatcaaat
     3361 tagctcgagc ttcgtatggg gtattggcgc ctcgtcaggc tttacagccc ggtcatcgca
     3421 gttctatgtg aactctcgat tgccaggccc aaatgccaaa cccgagattc tcaaaggtgg
     3481 cgtagtatac gctgactcag cgatgtgctc aagtcccgaa cagacaaaga tcccgaagga
     3541 tcgcgcatag cgggttaaat ccaaccgcgt tcggcaaaag aaacatactc tccacgccca
     3601 atcacgatat ggtcgagcac gcgtaaatcc atgaactgac aactctttat tatccgttca
     3661 gtaatgagtt tatccgcttt actgggttca gcacaacccg aagggtgatt atgtgcaagg
     3721 atcagcgccg aggcgtttat ttttatcgct tcgcggataa tttcccgagg atggacttca
     3781 acatggttta gcgtgccgga aaaaagacgg caatgcgtta taacccggtg ttgtgagtcg
     3841 agaaagatca ccataaagat ctcccgctcc tcacccgtga gctggctttg taaaaattcc
     3901 cgcgtcatct ccgggctgag taaagggctt tcttcacgca tccgcacgtt gtagtaacgc
     3961 cgcgccagtt cagcaatccc ctttaactgg gcaaatttcg ccacgccaat tccatgaacg
     4021 ccactaaatt gttcatattc agaggttaac aagccataaa gagagccgaa attctccagc
     4081 atctcttttg ccagggttaa tacatcttta ccgcgcgttc cggtacgcag aaatagcgcc
     4141 agcagctcga catccgttaa ggcgctaata ccaaacttca gcattttttc gcgcggcatc
     4201 aacagctgtg aattgttttt caccttcacc tcctttgtgg tgctcgcatc ctgtcatagc
     4261 cgttccgtta aatcgacggc cagttttcaa tcctggaaag cgcctcgcaa agtgattctc
     4321 aggtgaaggc acgacaacaa aagtattgtg ataaaatcgc caacttctgg tgtcacccaa
     4381 caggaaaaat catcatgagc ctggccggta aaaaaatcgt tctcggcgtt agcggcggta
     4441 ttgctgccta taaaacccct gaactggtgc gtcgtttgcg cgatcgcggg gccgacgtcc
     4501 gcgtagccat gaccgaagcg gcaaaagcct ttatcacccc acttagcttg caggcggttt
     4561 ctggttatcc cgtttccgac agtttgctgg acccggcagc cgaagccgct atgggccata
     4621 ttgagctggg taaatgggct gatttagtga ttctcgcccc tgccacggca gatttgattg
     4681 cccgtgttgc tgccggaatg gcgaatgacc tggtatcgac gatttgtctg gctacacctg
     4741 cgcctgtagc cgtgctcccc gccatgaacc agcagatgta ccgtgccgct gccacgcagc
     4801 ataatttaga ggtgcttgct tcccgtggtt tgctcatctg ggggccagac agtggcagtc
     4861 aggcttgtgg tgatatcggt cctgggcgaa tgctcgatcc gttaaccatt gtggatatgg
     4921 cggtggcgca tttttcgccc gtcaacgacc tgaaacatct gaacattatg attaccgccg
     4981 gtccgacgcg tgaaccgctc gatccggtgc gttatatctc taatcacagc tccggcaaga
     5041 tgggttttgc tatcgccgcc gccgctgccc gtcgtggcgc gaacgtcacg ctggtatcag
     5101 gtccggtttc actaccgacg ccaccgtttg ttaaacgtgt tgatgtgatg accgcgctgg
     5161 aaatggaagc cgccgtgaat gcttctgtac agcagcaaaa tatttttatc ggctgcgccg
     5221 ccgtggcgga ttatcgcgca gctaccgtgg ccccagaaaa aatcaaaaag caggccacgc
     5281 agggtgatga attaacaata aaaatggtta aaaaccccga tatcgtcgca ggcgttgccg
     5341 cactaaaaga ccatcgaccc tacgtcgttg gatttgccgc cgaaacaaat aatgtggaag
     5401 aatacgcccg gcaaaaacgt atccgtaaaa accttgatct gatctgcgcg aacgatgttt
     5461 cccagccaac tcaaggattt aacagcgaca acaacgcatt acaccttttc tggcaggacg
     5521 gagataaagt cttaccgctt gagcgcaaag agctccttgg ccaattatta ctcgacgaga
     5581 tcgtgacccg ttatgatgaa aaaaatcgac gttaagattc tggacccgcg cgttgggaag
     5641 gaatttccgc tcccgactta tgccacctct ggctctgccg gacttgacct gcgtgcctgt
     5701 ctcgacgacg ccgtagaact ggctccgggt gacactacgc tggttccgac cgggctggcg
     5761 attcatattg ccgatccttc actggcggca atgatgctgc cgcgctccgg attgggacat
     5821 aagcacggta tcgtgcttgg taacctggta ggattgatcg attccgacta tcagggccag
     5881 ttgatgattt ccgtgtggaa ccgtggtcag gacagcttca ccattcaacc tggcgaacgc
     5941 atcgcccaga tgatttttgt tccggtagta caggctgaat ttaatctggt ggaagatttc
     6001 gacgccaccg accgcggtga aggcggcttt ggtcactctg gtcgtcagta acacatacgc
     6061 atccgaataa cgtcataaca tagccgcaaa catttcgttt gcggtcatag cgtgggtgcc
     6121 gcctggcaag tgcttatttt caggggtatt ttgtaacatg gcagaaaaac aaactgcgaa
     6181 aaggaaccgt cgcgaggaaa tacttcagtc tctggcgctg atgctggaat ccagcgatgg
     6241 aagccaacgt atcacgacgg caaaactggc cgcctctgtc ggcgtttccg aagcggcact
     6301 gtatcgccac ttccccagta agacccgcat gttcgatagc ctgattgagt ttatcgaaga
     6361 tagcctgatt actcgcatca atctgattct gaaagatgag aaagacacca cagcgcgcct
     6421 gcgtctgatt gtgttgctgc ttctcggttt tggtgagcgt aatcctggcc tgacccgcat
     6481 cctcactggt catgcgctaa tgtttgaaca ggatcgcctg caagggcgca tcaaccagct
     6541 gttcgagcgt attgaagcgc agctgcgcca ggtattgcgt gaaaagagaa tgcgtgaggg
     6601 tgaaggttac accaccgatg aaaccctgct ggcaagccag atcctggcct tctgtgaagg
     6661 tatgctgtca cgttttgtcc gcagcgaatt taaataccgc ccgacggatg attttgacgc
     6721 ccgctggccg ctaattgccg cgcagttgca gtaatatgac gccggatgaa ttttcatccg
     6781 gcgagtttct ttaaacgcca aactcttcgc gataggcctt aaccgccgcc agatgttccg
     6841 ccatttccgg cttctcttcc aggtaagcaa tcagatcttt cagggtgatg atagagatca
     6901 ctttgcagtt gtaatcacgc tcaacttcct gaatcgccga aatctcgccg cgcccccgtt
     6961 cctgacgatc gagcgaaatc aacacgccag caagcgtcgc gccattggcc tgaataattt
     7021 ccatcgactc acgaatcgcc gttccggcgg tgatcacatc atctaccagc attacgcgtc
     7081 cttgtaacgc gctaccaacc agattgccgc cttcaccgtg gtcttttgcc tctttgcggt
     7141 taaagcagta cggcaggtcc aggtcatgat gctccgccaa cgccacggcg gttgtggtgg
     7201 caatcgggat ccctttgtaa gcagggccaa acagcagatc gaactcaatg ccggagtcca
     7261 ccaatgcttc agcgtaaaaa cggcctaaca gtgccaggtc gcgcccggta ttaaacagcc
     7321 cggcgttgaa gaaatagggg cttttacgcc cggatttcag cgtaaactcg ccaaacttta
     7381 acacctgctt gctaagcgca aattcaataa actggcgctg atatggtttc atgccttcgc
     7441 tcctcatctt acttttctac agacaaaaaa aagcgactca tcagtcgcct taaaaatcag
     7501 tttgccagcg ccgccttctg cgtcgctaca atggattcga ttccccctcg ggccagcgcc
     7561 aacaaggtga gtagctcttc atgggtgaac ggctcgcctt ctgccgtccc ctgcacttca
     7621 atgatgcgcc cgtcttcggt catcactacg ttcatgtcgg tctctgcggc agagtcttca
     7681 acgtattcca gatcgcaaac cgcttcgccg ttcacaatcc cgacagaaac cgcggctacc
     7741 atccctttca tcgggttggt tttcagcttg ccgttttcca ccagcttctg tagcgcatct
     7801 gccagcgcca cacaggcacc cgtaatcgaa gcggtacgcg tgccaccatc agcctgaagc
     7861 acgtcgcagt ccagcgtaat ggtgaactca cccagcgctt tcaaatctac tgccgcgcga
     7921 agcgcacggg cgatcagacg ctggatttcc attgtgcgtc caccctgctt acctttcgcc
     7981 gcttcacgag cgttacgggt gtgggtagaa cgtggcagca tgccgtactc tgcggtgatc
     8041 cagccctggc cctgaccttt caggaagcgc ggcacgcctt cttcaataga ggcggtacac
     8101 aacactttgg tatcgccaaa ttcgaccagc accgagcctt ctgcatgttt tgtatagtta
     8161 cgagtcaggg taacgggacg cacctgatta ttgctacggc ctgctggacg catattgaaa
     8221 tctccggctt gaaacaaatg tggctgcgca ttatacggac ttccggcggt tattcctatc
     8281 ctgacaaggc atcgatggct ataatccttc cacctctcct tttataaaca ggaacgtcta
     8341 tgatccgcag tatgaccgcc tacgcccggc gtgaaatcaa gggtgaatgg gggagcgcaa
     8401 cctgggaaat gcgctcggta aaccagcgtt atctggaaac ttactttcgt ctgccggagc
     8461 agttccgtag ccttgaacct gtcgttcgcg agcgtattcg ttctcgcctg acgcgcggta
     8521 aagtggaatg taccctgcgc tatgagccag atgttagcgc gcaaggtgag ctgatcctca
     8581 acgaaaaact ggctaaacag ctggtaactg ccgcgaactg ggtaaaaatg cagagtgacg
     8641 aaggggaaat caacccggtt gatattctac gctggccggg cgtgatggca gcccaggagc
     8701 aggatcttga cgccattgcc gctgaaattc tcgcggcgct ggatggtacg ctggacgact
     8761 ttattgtcgc gcgcgaaacc gaaggtcagg cactgaaagc attgatcgag cagcgtctgg
     8821 aaggcgtcac cgccgaagtg gtcaaagtcc gctcccatat gccggaaatc ctgcaatggc
     8881 agcgtgaacg cttggtcgcg aagctggaag atgctcaggt tcagttggaa aacaaccgtc
     8941 tggagcagga gttggttctg ctggcacaac gaattgacgt tgccgaagaa ctggaccgcc
     9001 tcgaagcgca tgtcaaagag acctacaaca ttctgaagaa aaaagaagcc gttggtcgtc
     9061 gtctggactt tatgatgcag gagttcaacc gcgagtcgaa cactcttgcg tcgaagtcta
     9121 tcaatgccga agtgacaaac tccgcgattg agctgaaagt gttgattgag cagatgcgcg
     9181 agcagattca gaatattgaa taactcgtaa cgccaattct tacttttcag ccttcacaaa
     9241 tgccgcccac tcaaacagag cggcattttt cttccccgca actttcaatt ctgtttttcg
     9301 tgccagctcc agattttgcg atgttttttt gcccagcaca ctgagaacgt gagatactca
     9361 caactgtata taaatacagt tacagattta ctttctttgc aattgatatc acatggagtg
     9421 ggcaatgaac gaacatcatc aaccttttga agagataaaa ctgattaatg caaacggagc
     9481 agaacaatgg tcagcaagac aacttgggaa actactgggt tattcagagt atcgtcactt
     9541 tatacctgta ttaacgcgcg ccaaagaagc ctgtgagaac agtggtcaca caattgatga
     9601 ccatttcgag gagatcctcg atatggtcaa aattggctca aatgccaaaa gagcattaaa
     9661 agacatcgta ctctcccgct atgcctgtta cctggtagta caaaacggcg accctgcgaa
     9721 accggtcatt gcggcagggc agacttattt tgctatccag acccgacggc aggagcttgc
     9781 tgacgatgaa gcatttaagc aacttcgtga agacgaaaag cgtctgtttc tgagaaatga
     9841 gttgaaagaa cataacaaac aattggttga ggcagcacag caagctgggg tagcgacagc
     9901 tactgatttc gccatatttc agaatcatgg ttaccagggg ctgtatggtg gattagatca
     9961 gaaagctatt catcagcgga aggggctgaa aaagaatcag aagatcctgg atcatatggg
    10021 ttcaacagaa ctggcggcta atctctttcg agctacccaa acagaagaaa aactcaagcg
    10081 ggatggcgtg aattcaaaac agcaagctaa taccacacac tttgacgtgg gtagcaaggt
    10141 gatgcaaacc attcaggaac ttggcggaac catgcctgag gagttgccga ccccgcaggt
    10201 cagcatcaag cagttggaaa acagtgtaaa aattacagag aagaaatagc agaaactaaa
    10261 aactcttttt gttgattgag atacccgatg cgtaagccaa agtccaggtg cggtgaacac
    10321 aatggctaaa cattgcacct ttcttttcca cccctcaatt ttaacctatt ttttcttatg
    10381 cattttctca gacaagaagt cagaagaatg catctacgct acagaaaata gcgatttcac
    10441 ataactacaa gttatcaatt tcctctcacc ttaaaaaatc tcaatcgtga caatacgcac
    10501 aaatcgctac cctgccagac agatttttag ggagagaacc atgctgttac acattttgta
    10561 tttggttggc attactgccg aagccatgac gggggctctg gcggccgggc gacgccgcat
    10621 ggatacattt ggcgtaatta ttattgcgac cgccaccgca attggcggag ggtcagtgcg
    10681 cgatattctg ctgggccact atccgctcgg ctgggtcaaa cacccggaat atgtgattat
    10741 cgtcgctacc gccgcagtac tcaccactat cgttgctcct gtaatgcctt acctgcgcaa
    10801 agtgtttctg gtgctcgatg cgcttggact ggtggtcttt tctatcatcg gcgcacaggt
    10861 tgcactggat atggggcacg gcccaattat tgccgttgtc gcggcggtaa ccaccggcgt
    10921 gtttggcggc gttttgcgcg atatgttctg taaacgtatc ccactggtat tccagaaaga
    10981 gttgtatgcc ggtgtctcat ttgcctccgc cgtgctgtac atcgcgctgc aacactatgt
    11041 ttctaaccat gatgtggtaa ttatctccac cctggtattc ggcttttttg cccgcttact
    11101 ggcgctacgc cttaagctgg gattaccggt cttttactac agccacgaag gacactaagg
    11161 ttcaaaacct gtgatctgct gggcagccag ccaactgccc agcttcttga tttgcgcatt
    11221 ttccttccat tcaataacct gtctggcgcg tcccgatcca gtccccggca gctgctgcca
    11281 gaactgctcc gtgctaaata aaagttgcga ccaggaccgt tcatcactgg cattaagcgc
    11341 cgcccgggtt agcggtattc ccattgccat cacccagcga gtaaaaggct gcttacgagc
    11401 cagattaaac tgatgccata gctgcgcact tttacttttc gcgatccccg gcgtgttctg
    11461 taattgctct ggcgttaata aaagccagga aaagatatgt tcaaagcgat gagtctgatg
    11521 cagcgcgcgc caaccggcct caccaatgcc atccagcccc agaacctgtt ttgaccccag
    11581 ccagactaag cgtgaaatga actgttcctg acaaacatca gaagcaaagt agcaggtcaa
    11641 cgagttaaag cggttttctg gtggtgtcgg ttttgtacgt tctgcaccgc gccagaccac
    11701 atcatcaatg cgaggaatac cctgaccggc aaggctgacg aggatctgat caccaggcgc
    11761 aatatcccac tcctgccagc gcctgacgga accaatattc acccgctgga cttttttatc
    11821 atccagcatg acaggtgcga gtgacgcaac caccgatatt ttaccgctct tacccaccgc
    11881 aaactgaatc gccttcactt cggcaacctg agctacaggt tgatatttcc aggccaccag
    11941 ccactctgcc tggcccggta gccaatggcg ggattctggc tctttcgccg ctcgtacaac
    12001 tacgccatcg gtgacgaagg gtaattccgc tttccaccac tcattgcgta cgcgcgcaac
    12061 ttcatcagca tttttcaccg cacgggtata cgtctgcgtt agagtaaaac ctgcggtagc
    12121 cagctctttt aaacgatcag acattaactg cggtccatcc ggccatgccc agacaaaaac
    12181 gcccagagaa ttcagcgtgt cgctatcgtc ctggcgcatc atcaagccag caacttttgc
    12241 gcgggcattt attcccccca tttgttgttg gatatgcccc tcgcgctgga gaaatatttc
    12301 cccctgaagc gtactgttgg ctaaaggccc gctaacggtt tgcggcacag cggaaattaa
    12361 gctaactttc tgcgtccagt cctcgccttt caggccatta ccgcgactga ttgctttgtt
    12421 cagtttcccg tcccgataaa ccagggttac cgcaacgcca tcaacttttg gctgcaccca
    12481 aagatcgcta cgttctcgca tccacagact taatgcgttt ttatccacca ttttgcgtac
    12541 acccgtatgg gcaaccggat gcataaccgc accatttaaa ggcggcatca tcacgtcgcg
    12601 gggctcgctc ccaaagcagc gttgccactg cgtaagacgg gcgcttaact gatcgtaaac
    12661 accgtcttcc acctcacttt ttccttcctt ccagtagtca tcgtcccact gttttatttg
    12721 ctgttgcagg cgggaaattt cttcctgtgc tctggctggc gaccaggccg gacagaccgc
    12781 ccacacagat gattgccagc acaagatact tattaatatc gccatccata ctttcatcat
    12841 cacctccgct gtaggtagtc aggcagatat acaacgtgat gaaagcaaag ccgagtggca
    12901 aaaacggagt ctgcgaggac gcttcctgaa aatcgtcttt attgcagtga atgacaggca
    12961 aatgcggaag cagctacgca aaacgcaaca actttgcgca aaaagtgtga gcaagggcta
    13021 cgtcacatgg ccgcgccgtg tataataagc tcgtatgtag gctttatttc gctaatcaca
    13081 tacgaaagat actcatggct caaggcacgc tttatattgt ttctgccccc agtggcgcgg
    13141 gtaaatccag cctgattcag gctttattaa aaacccaacc gttgtatgac acccaggttt
    13201 ctgtttcaca caccacacgc caaccgcgtc ctggtgaagt ccacggtgaa cattatttct
    13261 ttgttaatca tgatgaattt aaagaaatga ttagcagaga tgcgttcctc gaacacgcag
    13321 aagtttttgg taattactat ggcacttcgc gtgaggccat tgagcaagta ctggcgaccg
    13381 gtgtcgatgt ttttctcgat atcgactggc agggcgcgca gcaaattcgc cagaagatgc
    13441 cgcacgcccg gagtatcttt attttaccgc cgtccaaaat tgaactggac cgccgtctac
    13501 gcggtcgcgg tcaggacagc gaagaggtca ttgcaaagcg tatggcgcaa gctgttgcag
    13561 aaatgagcca ttacgccgaa tatgattatc tgattgtgaa tgatgacttc gataccgcgt
    13621 tgaccgattt gaagaccatt attcgcgccg aacgtctgcg catgagccgc caaaagcagc
    13681 gtcatgacgc tttaatcagc aaattgttgg cagactgaac ctgatttcag tatcatgccc
    13741 agtcatttct tcacctgtgg agctttttaa gtatggcacg cgtaactgtt caggacgctg
    13801 tagagaaaat tggtaaccgt tttgacctgg tactggtcgc cgcgcgtcgc gctcgtcaga
    13861 tgcaggtagg cggaaaggat ccgctggtac cggaagaaaa cgataaaacc actgtaatcg
    13921 cgctgcgcga aatcgaagaa ggtctgatca acaaccagat cctcgacgtt cgcgaacgcc
    13981 aggaacagca agagcaggaa gccgctgaat tacaagccgt taccgctatt gctgaaggtc
    14041 gtcgttaatc acaaagcggg tcgcccttgt atctgtttga aagcctgaat caactgattc
    14101 aaacctacct gccggaagac caaatcaagc gtctgcggca ggcgtatctc gttgcacgtg
    14161 atgctcacga ggggcaaaca cgttcaagcg gtgaacccta tatcacgcac ccggtagcgg
    14221 ttgcctgcat tctggccgag atgaaactcg actatgaaac gctgatggcg gcgctgctgc
    14281 atgacgtgat tgaagatact cccgccacct accaggatat ggaacagctt tttggtaaaa
    14341 gcgtcgccga gctggtagag ggggtgtcga aacttgataa actcaagttc cgcgataaga
    14401 aagaggcgca ggccgaaaac tttcgcaaga tgattatggc gatggtgcag gatatccgcg
    14461 tcatcctcat caaacttgcc gaccgtaccc acaacatgcg cacgctgggc tcacttcgcc
    14521 cggacaaacg tcgccgcatc gcccgtgaaa ctctcgaaat ttacagcccg ctggcgcacc
    14581 gtttaggtat ccaccacatt aaaaccgaac tcgaagagct gggttttgag gcgctgtatc
    14641 ccaaccgtta tcgcgtaatc aaagaagtgg tgaaagccgc gcgcggcaac cgtaaagaga
    14701 tgatccagaa gattctttct gaaatcgaag ggcgtttgca ggaagcggga ataccgtgcc
    14761 gcgtcagtgg tcgcgaaaag catctttatt cgatttactg caaaatggtg ctcaaagagc
    14821 agcgttttca ctcaatcatg gacatctacg ctttccgcgt gatcgtcaat gattctgaca
    14881 cctgttatcg cgtgctgggc cagatgcaca gcctgtacaa gccgcgtccg ggccgcgtga
    14941 aagactatat cgccattcca aaagcgaacg gctatcagtc tttgcacacc tcgatgattg
    15001 gcccgcacgg cgtgccggtt gaggtccaga tccgtaccga agatatggat cagatggcgg
    15061 agatgggtgt tgccgcgcac tgggcttata aagagcacgg cgaaaccagt actaccgcac
    15121 aaatccgcgc ccagcgctgg atgcaaagcc tgctggagct gcaacagagc gccggtagtt
    15181 cgtttgaatt tatcgagagc gttaaatccg atctcttccc ggatgagatt tacgttttca
    15241 caccggaagg gcgcattgtc gagctgcctg ccggtgcaac gcccgtcgac ttcgcttatg
    15301 cagtgcatac cgatatcggt catgcctgcg tgggcgcacg cgttgaccgc cagccttacc
    15361 cgctgtcgca gccgcttacc agcggtcaaa ccgttgaaat cattaccgca ccgggcgctc
    15421 gcccgaatgc cgcgtggctg aactttgtcg ttagctcaaa agcgcgcgcc aaaattcgtc
    15481 agttgctgaa aaacctcaag cgtgatgatt ctgtaagcct gggccgtcgt ctgctcaacc
    15541 atgctttggg tggtagccgt aagctgaatg aaatcccgca ggaaaatatt cagcgcgagc
    15601 tggatcgcat gaagctggca acgcttgacg atctgctggc tgaaatcggc cttggtaacg
    15661 caatgagcgt ggtggtcgcg aaaaatctac aacatgggga cgcctccatt ccaccggcaa
    15721 cccaaagtca cggacatctg ccaattaaag gtgccgatgg cgtgctgatc acctttgcga
    15781 aatgctgccg ccctattcct ggcgacccga ttatcgccca cgtcagcccc ggtaaaggtc
    15841 tggtgatcca ccatgaatcc tgccgtaaca tccgtggcta ccagaaagag ccagagaagt
    15901 ttatggctgt ggaatgggat aaagagacgg cgcaggaatt catcaccgaa atcaaggtgg
    15961 agatgttcaa tcatcagggt gcgctggcaa acctgacggc ggcaattaac accacgacct
    16021 cgaatattca aagtttgaat acggaagaga aagatggtcg cgtctacagc gcctttattc
    16081 gtctgaccgc tcgtgaccgt gtgcatctgg cgaatatcat gcgcaaaatc cgcgtgatgc
    16141 cagacgtgat taaagtcacc cgaaaccgaa attaatgttt tatgaaccca acacgttatg
    16201 cacgcatctg cgaaatgctc gccaggcggc agcctgacct gaccgtctgc atggagcagg
    16261 tccacaaacc tcataacgtt tctgcgatta ttcgtaccgc agatgccgtt ggcgtacatg
    16321 aagttcacgc cgtctggcct ggtagccgga tgcgcaccat ggcttcggca gcggcgggta
    16381 gtaacagctg ggtacaggtg aaaacacacc gcaccattgg cgatgccgtc gctcatctga
    16441 aaggccaggg catgcagatt ctggcaaccc atctttctga taatgctgtc gatttccgcg
    16501 aaattgatta cactcgcccg acctgcattt tgatgggaca ggagaaaacg ggcatcacgc
    16561 aggaagcatt ggccctggcg gatcaggaca tcatcattcc gatgatcggc atggtgcagt
    16621 cgctgaatgt ttccgttgcc tcagccctca ttctttacga agcccagcgt cagcggcaaa
    16681 atgcaggcat gtacctgcgt gaaaacagca tgttgccgga agcagagcaa caacgcctgt
    16741 tgtttgaagg cggctatccg gtgctggcga aagtcgcaaa acgcaaaggc ctgccttacc
    16801 cccacgtcaa tcagcaaggc gagatcgaag ctgatgctga ctggtggtcc accatgcagg
    16861 ccgcagggta agcgccatga aaggccgcct gttagatact gtcccgctca gttccctaac
    16921 gggcgttggc gcagcgctta gtaacaaact ggcgaaaatc aacctgcata ccgtgcagga
    16981 tttactctta caccttcccc tgcgctacga agatcgcacc catctctacc ccatcggaga
    17041 actactgccg ggcgtttatg ccacggtgga aggcgaagtg ctgaactgca atatctcctt
    17101 cggcggtcgg cggatgatga cctgccagat cagcgacggt tccggcatcc tcaccatgcg
    17161 ctttttcaat ttcagcgcgg caatgaaaaa tagcctggcg acgggccgcc gtgtactggc
    17221 ttatggcgaa gcaaagcgcg gtaaatatgg tgcggagatg atccacccgg aataccgcgt
    17281 gcagggcgat ctcagcacgc cagaattaca ggaaacgctc acgccggttt atccaacaac
    17341 ggaaggcgta aagcaggcca cgctgcgtaa attaaccgac caggcgctgg atctgctcga
    17401 cacctgcgcc attgaagaac tcctgccgcc ggaactgtca caaggaatga tgacgctacc
    17461 ggaagcgttg cgcactttgc accgcccgcc accgacgcta cagcttagcg atctggaaac
    17521 cgggcagcat ccggcgcaac gtcgtctgat tctggaagaa ctgctggcgc acaacctcag
    17581 catgttagcc ttacgtgccg gagcacagcg ttttcatgcc cagccgctga gcgccaatga
    17641 cacgctgaaa aataaactcc tcgccgcctt accgttcaag ccaacgggcg cacaggcacg
    17701 cgtagtggcg gagatcgagc atgatatggc gctggatgtg ccgatgatgc gcctggtaca
    17761 gggcgatgta ggttccggta aaacgctggt cgccgccctc gccgcgctgc gtgcgattgc
    17821 ccacggcaaa caggtggcac tgatggcacc aaccgaatta ctcgccgagc agcacgccaa
    17881 taacttccgc aactggtttg caccgctcgg tatcaaagtg ggctggctcg ccggtaagca
    17941 gaaaggcaaa gcgcgactgt ctcagcagga agccatcgcc agcggtcagg tgcagatgat
    18001 tgtcggtaca cacgccatct tccaggaaca ggtgcagttt aacggcctgg cgctggtgat
    18061 tatcgacgaa cagcatcgtt ttggcgtgca tcagcgtctg gcattgtggg agaaaggcca
    18121 gcagcagggc ttccatccgc atcagttgat catgaccgcc acgccgatcc cccgcacgct
    18181 ggcaatgacg gcgtatgccg atctcgatac ctcggtgata gatgagctgc cgccaggccg
    18241 cacgccagtg actacggtcg ctattcctga tacccgccgt accgacatca ttgaccgcgt
    18301 gcgccacgcc tgcataactg aaggtcgtca ggcgtactgg gtttgtacgt tgattgaaga
    18361 gtcagagtta ctggaagcgc aggcggcgga agctacctgg gaagagttga aactggcgct
    18421 accagaattg aatgttggcc tggtacacgg gcggatgaaa ccagccgaga aacaggcggt
    18481 gatggcgtcg tttaaacaag gtgagctaca tctgctggtt gccactaccg ttattgaagt
    18541 cggtgttgat gtgcctaacg ccagcctgat gattatcgaa aaccctgagc gtctgggtct
    18601 ggcgcagtta caccagctgc gcgggcgcgt aggtcgtggc gcggtggctt ctcactgcgt
    18661 gctgctctac aaaacgccgc tttctaaaac ggcgcaaatt cgcctgcaag tgctgcgcga
    18721 cagtaacgac ggttttgtga ttgcgcaaaa agatctggag attcgcggcc ctggcgaatt
    18781 gttaggcacg cgtcagacgg gtaatgctga atttaaagtg gcggatttac tgcgcgatca
    18841 ggcgatgatc ccggaagttc agcgcctggc gcgacatatt cacgaacgtt acccacaaca
    18901 ggcaaaagcc ttgatagaac gctggatgcc ggagacagaa cgttactcga atgcgtaaaa
    18961 ggcggcagtg agaagaccgc catttcaggt taccctacct tcctgccgga tgcgattcac
    19021 cctacaaatt caataaatta tgaatcaata cgcaggcttg ataagcgaag cgtatcaggc
    19081 atttgtcttt gttgcggcgg cacttctacc gccgcttcat cggttaaccg gcaaaaatcg
    19141 gcaacatcaa atacaactta attaccagcg cattgacgat atcgataaag aacgcaccga
    19201 ccatcggcac caccaaaaac gccatgtgcg acgggccaaa gcgttcagtg atcgcctgca
    19261 tgttggcgat tgccgttggc gttgcaccga ggccaaaacc acagtgaccc gcagccagca
    19321 ctgccgcatc gtagtttttg cccatcatgc gccaggtaac gaagatggca tacaacgcca
    19381 tgaagatggt ctgtaccacc agaatcgcca gcatcggcag cgccagcgaa gccagctccc
    19441 acagtttcag ccccatcaac gccatcgcca ggaacaacga caagcttacg ttacccagca
    19501 cggataccgc acgctcaaag acgcggtaaa agcccattat tgacagaccg ttgctcagaa
    19561 tcacgccaac aaacagtaca cagacgaagg tcggcagttc aaaagcagtg ccagccaaaa
    19621 gttgcgcaac aattttcccc accgtcaggc agatagcaat cagcgcgata gtttcaatca
    19681 gcaccaacga ggtgatcatg cggcccacat ccggcttttc aaacgccgtc gggacttcct
    19741 ggtcatccgg aataccgttc ggcgtggtgg agtgtttcac cagatagcgc gccaccggac
    19801 cgccaatcaa gccgcccagc accagaccga acgttgcaca ggccatcgcc acttccgtcg
    19861 cattggtgaa gccataacgt tcaatgaaca atttactcca cgcagcgccc gtaccgtgac
    19921 cgccggaaag cgtaatagaa ccggccaaca gccccatcag cggatcaagc cctaacaggc
    19981 tagccatacc aatgccaatg gcattttgca tcaccaacag accaacaacc acaatcaaga
    20041 agatgccaac cacacgccca ccggcacgca aactggcaat gttggcgttc aggccaatgg
    20101 tggcgaagaa agccagcatt aacggatcgc gcagggacat atcaaagttg acttcccagc
    20161 ccatgctttt tttcagtact agtagcgcca gcgccaccaa caaaccaccc gcaacaggtt
    20221 ccggtatggt gtatttcttc aaaaaggaga cggaatggac caacttacgc ccgagcagca
    20281 acgtcagcgt tgcggcaaca agcgttgcta aagtatcgag atgaaacata gttactcctt
    20341 tgtatccgca tcactctttc atactcgtca tacttcatcg cgcagtggca acttcatgaa
    20401 ctatgacggg tatcgagtta tgctttcctg ggtcaaattc tcagctgtta atgaacaaat
    20461 ggcatggatt ttaagcagaa aaataccaaa agttatataa aaaagtgcat ttatctcatt
    20521 taaatattta gatgaggatg tggcaaacgt ttgcttttct ctttcggtca gctaaaatgc
    20581 ccgctttgct accacgggat tgttttcgat gtctgtttcc accctcgagt cagaaaatgc
    20641 gcaaccggtt gcgcagactc aaaacagcga actgatttac cgtcttgaag atcgtccgcc
    20701 gcttcctcaa accctgtttg ccgcctgtca gcatctgctg gcgatgttcg ttgcggtgat
    20761 cacgccagcg ctattaatct gccaggcgct gggtttaccg gcacaagaca cgcaacacat
    20821 tattagtatg tcgctgtttg cctccggtgt ggcatcgatt attcaaatta aggcctgggg
    20881 tccggttggc tccgggctgt tgtctattca gggcaccagc ttcaactttg ttgccccgct
    20941 gattatgggc ggtaccgcgc tgaaaaccgg tggtgctgat gttcctacca tgatggcggc
    21001 tttgttcggc acgttgatgc tggcaagttg caccgagatg gtgatctccc gcgttctgca
    21061 tctggcgcgc cgcattatta cgccgctggt ttctggcgtt gtggtgatga ttatcggcct
    21121 gtcgctaatt caggttgggt taacgtccat tggcggcggt tacgcagcca tgagcgataa
    21181 caccttcggc gcaccgaaaa atctgctgct ggcaggcgtg gtcttagcct taattatcct
    21241 gcttaaccgt caacgtaacc cttacttacg cgtggcctca ctggtgattg cgatggcggc
    21301 cggatatgcg ctggcgtggt ttatgggcat gttgccagaa agcaacgaac cgatgacgca
    21361 agaactgatt atggtgccaa cgccgctcta ttacggtctt ggcattgaat ggagtctgct
    21421 gctgccgctg atgctggtct ttatgatcac ttcgctggaa accattggcg atatcacggc
    21481 gacctctgac gtttccgaac agccagtgtc cggtccgctg tacatgaaac gcctgaaagg
    21541 tggcgtgctg gcaaacggcc tgaactcgtt tgtttcggcg gtgtttaaca ccttcccgaa
    21601 ctcctgcttc gggcaaaaca acggagtgat ccagttgact ggtgttgcca gccgctatgt
    21661 cggttttgtc gtcgcgctga tgttgatcgt gctgggtctg ttcccggcag tgagcggttt
    21721 tgtacaacac attccagaac cggttctggg cggcgcaacg cttgtaatgt ttggcaccat
    21781 cgccgcctcc ggtgtgcgta tcgtttctcg tgagccgctg aaccgtcggg cgattctgat
    21841 tatcgcgctg tcgctggcgg ttggtctggg cgtgtctcag cagccgctga ttttgcagtt
    21901 tgcccctgaa tggctgaaaa acctgctctc ctccgggatc gccgcgggcg gtattactgc
    21961 catcgtgctg aatctgattt tcccaccaga aaaacagtaa ttcactggcg gcggtaagat
    22021 aattaccgcc gcagtctcac ctctttcacc attcccgcct tgaggattgc gcgtaaatcg
    22081 tgcataactc ccttatgtgc atttcacggg atggaagacc atgaaattta ttgggaagct
    22141 gcttctctac attctcatcg ctctgttagt ggtgatcgct ggcctctatt ttcttctgca
    22201 aacccgctgg ggagcagaac atatcagcgc atgggtttcc gagaatagcg actatcatct
    22261 ggccttcggg gcgatggatc accgtttttc cgcgccatct catatcgtgc tggagaatgt
    22321 cacgtttggt cgtgatggcc agcccgcgac cctggtggcc aaaagtgtcg acattgcgct
    22381 aagtagtcgg caactgaccg aaccacgcca tgtcgatacc atcctgctgg aaaacgggac
    22441 gctgaatctc accgaccaga ccgcgccgct accgttcaaa gccgatcgtc tgcaactgcg
    22501 tgatatggcg tttaatagcc cgaatagcga atggaaactg agcgcgcagc gggtaaatgg
    22561 cggcgtggtt ccgtggtcac cagaagccgg taaagtgctg ggtacgaagg cgcagattca
    22621 gtttagtgcc ggatcgcttt cgctcaatga tgttcctgcc accaatgtac tgattgaagg
    22681 cagtattgat aacgatcgcg ttacgctgac taacctgggt gccgacatcg cgcgcgggac
    22741 attaaccgga aacgcgcagc gtaacgccga cggcagctgg caagtggaaa acctgcgcat
    22801 ggcggatatc cgtctacaaa gcgaaaaatc gctaaccgac ttctttgcgc cattacgctc
    22861 tgtcccgtcg ttgcagattg gtcgcctgga agtgatcgat gctcgtttgc aaggtccgga
    22921 ctgggcggtg accgacctcg atctcagctt gcgcaacatg accttcagta aagatgactg
    22981 gcagacacaa gaaggcaaac tgtcgatgaa cgctagcgag ttcatttatg gttcgctgca
    23041 tttatttgac ccgattataa acgcggaatt ttccccgcag ggcgtagcgc tgcgccagtt
    23101 caccagccgc tgggaagggg gtatggtcag aacgtcaggg aactggctgc gtgacgggaa
    23161 aacgttgatc cttgatgatg cggcaattgc cgggctggaa tataccttgc cgaaaaactg
    23221 gcaacagttg tggatggaaa cgacacccgg ttggttaaac agcctgcaac tgaagagatt
    23281 tagcgccagc cgcaatctga tcattgatat cgaccctgac ttcccgtggc agctcaccac
    23341 gctcgatggt tacggtgcca acctgacgct ggttaccgat cataaatggg gcgtctggag
    23401 tggctcggcg aatctgaatg ccgccgccgc gacattcaat cgtgttgatg ttcgtcgccc
    23461 gtcgctggcg ctgaccgcca acagcagcac ggtgaatatc agcgaactga gtgcatttac
    23521 tgaaaaaggc attctggaag ccactgccag tgtttcacaa acgccacaac gtcagaccca
    23581 tatcagcctg aatggacgcg gtgtgccggt gaatattttg caacaatggg gatggcctga
    23641 attaccgttg actggcgacg gcaatattca gcttaccgcc agtggagata ttcaggccaa
    23701 tgccccgctg aaacctacgg ttagcgggca attgcatgcc gtgaacgccg caaagcagca
    23761 agtgactcaa accatgaatg ctggcatcgt ttccagcggt gaagttacat cgacggagcc
    23821 ggtgcggtaa acatcaatct cgccgggtac gactcagacg tacccggcat tccatcaata
    23881 gattacaacg taattgtcag cgcattccct tgaggcttca ccaccagccc ctgctcactt
    23941 tcagcctgcg aaccgtcttg cagaccattt actttcacaa cattgcgcag gcacagtgtc
    24001 cagttcttcg cctcgcccgc accagtcaca gtaatcgtgt tgccagtacg tgctgctttt
    24061 aaagtaaaga tcaccgatcc gtcagcagcg ggcacttcac agacggcttc atgcccgtct
    24121 tgcagattaa agaggtggaa tgccgtgcct tcgtgccaca cgtaatcggg acgttgatcg
    24181 ttgttgccca gcgccagtag agtgttatca cgcacataaa cgggcagact caggaagccg
    24241 tgctgctgtt tatgccagcg actaccgtcg agttcatcgt tgtgccacag gtgtgtccag
    24301 cgaccttccg gcaggtagaa ctgcacatcg cccgcttcag tgaacaccgg cgcaaccatc
    24361 acgttgtcgc ctaacatgta ttgacggtca aggtaatcac aagccggatc gtccgggaac
    24421 tccatcatca tggcccgcat catcggcgta ccccgcgcgt tcgcacgcgc agcttcacga
    24481 tacagatacg gcatcatgcg gcatttcagt tgcgtgaaga agcgcaccac atcacaggac
    24541 tcatcatcgt aggcccacgg cacacgataa gatttgctac cgtgtaaacg gctatggctg
    24601 gagagcaaac caaacgcgca ccagcgtttg taaacgtgcg ccggagcggt attttcaaag
    24661 ccgccgatat cgtggctcca gaagccaaaa cctgaaaggc caatagacaa accaccgcgc
    24721 aggctttccg ccattgattc gtagttagcg taacaatcgc caccccagtg taccgggaat
    24781 ttctgcgcac cgacggaggc cgagcgggca aacaagacag cttcttcctc accaacggtg
    24841 tccttgagca cgttccacac cagttcgttg tagatgtacg cataatggtt atgcattttc
    24901 tgcggatcgg aaccgtcaaa ccactgaaca tcagttggga tacgttcgcc aaagtcggtc
    24961 ttaaagcaat caacgcccat cgcgaccaga cctttcagtt tgtcggcgta ccatttgcag
    25021 gcatccggat tggtaaagtc ataaatcgcc agacctggct gccatttatc ccactgccat
    25081 agcgaaccgt ccgggcgttt gagtaaatag cctttctctt gtaactcttt aaagacgggg
    25141 gatttttgac cgatataggg gttaatccag acgcagattt tcagcccttt cgctttcagg
    25201 cggcggatca tcccttccgg gtcagggaaa gtcagcgggt cccactcaaa atcgcaccac
    25261 tggaaggctt tcatccagaa acagtcaaag tggaaaacat gcagcggcag attgcgttcc
    25321 gccataccat cgataaagct gtttaccgtc gcttcgtcgt agttggtggt aaatgaagtg
    25381 gttagccaca ggccgaagga ccacgcgggc ggcagcgccg gacgaccagt aaagcgggta
    25441 taacgatcaa gtaccgcttt cggcgtcggg ccgtcgataa caaagtattc gagatattca
    25501 ctctcaacgc tgaactgcac tttggagact ttctccgatc ccacttcaaa agagacacac
    25561 tggggatgat tgaccagtac cccataacca cggttagtca tgtagaacgg gatattttta
    25621 tacgcctgtt cagtacttgt gccgccgtcc cggttccagg tctctaccgt ctggccattg
    25681 cgcaccaggg cagtaaagcg ctctcccaga ccgtaaactg tttcgccaac gccaagatca
    25741 agccgctcaa acatataatt gcgttgatta ttcgtgtcct gcacgtagcc attatttttc
    25801 acctgactac cggtaatacg ttcgccgttg cgcagaaaat ccagtgacca gaactcacct
    25861 ttgctgacac gcgcgcttaa gttgccactt ttaaactcag cataacgttc tgtgttttcg
    25921 attgtgacct tcacgtcctg caaaatattg agcggataat gaggaccgtt attcagcgcc
    25981 ccctgaaaat gctcaatccg cacaccgaca ataccttcct gtggggagaa aaagcgcagc
    26041 gtaaataaag gcgtatcaag ctgccaggta cgttcacgca catcacgggg ggcagcatag
    26101 accaccattt cattatcctg ctgttcaacc tcgaacacct gaagcgggtg aatcaaattg
    26161 aggccaggtt gaatcaacca gtttccatcg ctaattttca ttgccgttcc ttagttctgc
    26221 acttcttgag aggtgaattg ttgctggcaa cggcgtttac cctgagccag ctgttccata
    26281 acggttttca gattgtgcgt cgtgagtgag tagtagcgtt tagcgataat cgcgctcagc
    26341 aaataacaga tcgccggaac aatcgtgaat agcgcaataa tgatgctaat cgtggcgctg
    26401 ttctgcgctt tttctgccgc atcatatccg ccataagcca gcatccagcc gataagagcg
    26461 ccgccgaagg ccaaccccag tttgagcaca aacagcgtgc cagcaaaact gatcccggtc
    26521 aggcgtttac cattgcacca ctcgccgtag tcgacggtat cggacatcat tacccactgg
    26581 ataggtgtca ccagttgatg caacacacca atcacgaaga tgaagacaaa catagtgatg
    26641 ctggcctgca tgggaacaaa gaacatcgcg aggctaatca ctgccagcag ggcgttcgtc
    26701 caccagaaga tagtgacttt acatttccag tcggtcagag gttttgccag tgcggaacca
    26761 atcaggttac ccacgcaata agtggtgaga aaagcgacaa acacttccgg cgtgcccaaa
    26821 atccatgtga cgtaatacat catcgcccca ccgcgtacgc acaccgccag gatattgaaa
    26881 atggttagta aaccgacaat ccgccactgg tcgttttgcc agatatcacg taaatcttcc
    26941 cgcatagacg ttgttgtagg tggtgcttca acgcgttctt tagtggtgaa gaaacaaaat
    27001 gccagcatca tgaatgccac cacggaaagg accgcgatac cgccctggaa accgagtggt
    27061 ttattatcac cgccaattaa attaaccagt ggcatcatca gaacagtaga aagcatgcct
    27121 cccgcggtcg ccagcacaaa acgccaggat tgcagcgaga tacgctgagt cgggtcattg
    27181 gtgattacac cacccaatgc gcagtaaggg atattgacga cggtataaag taaggtaagt
    27241 agggtgtaag taattgctgc atagatcatt ttgccgttca tactgagatc tggcgtgcta
    27301 taggccagta cacagacgat cccgaatggc agtgcgccaa acagtaccca cggacgaaat
    27361 ttaccccagc gagagcgcgt tcgatcggcc aacaacccca tgcaaggatc ggaaatcgca
    27421 tccagtgcac gagcgaccaa aaacatggtt ccgacaaaac cggcaggaat gccaaaaata
    27481 tcggtataaa agaacatcat atataacatt acgttatcga aaataatgtg gctggcggcg
    27541 tctcccatgc cataaccaat tttctcttta acggacaaca cttcactctt catctgcttt
    27601 tccttgatgc tataggggtg ctgagaccga taacgcattt tgtaaaccat ccctgtgaga
    27661 gcgaatattc cgatatctgg ttattaattt atgattcttg ttttatgtga tcgtggtagc
    27721 gttaattccg ctcatatatc attgtaaaat atgggtttta tatgaactat aatgctttcg
    27781 tgataatacg ctgcgtgtat taggcggaaa aaactgatct gggggatgta gaaactcaag
    27841 gaagtagcta taatgcgccc cgcctccatg tagcaatcga ggcgcggaag atcgtcgtct
    27901 ccggtgaggc ggctggactt caaatccagt tggggccgcc agcggtcccg ggcaggttcg
    27961 actcctgtga tcttccgcca aaatgcctct cctgacgttc tccaacccct tgtaatactg
    28021 tcaatccaga tattttctac tgctcaatat tcaatcggct tcaggaatac ctggtctaag
    28081 gttttgtgat ggacgatgag cggctgaaga atccgcctgt cggttcttct gtcctcgaac
    28141 gcatccgcga tattcacgcc agtatgcgcc gtgtttattt gcaggtgatt tgcccccctg
    28201 ctgactctca gccaactgta tcgccattaa ggtgaagatg ttgttttact cgccccagaa
    28261 cacccttttt tatacgacta ttctatttct ttaaccgctg gcgaaaaaaa ctgactataa
    28321 acttcaccaa taatcagact gccatcaaga ttaatttgtt catttaatat atcaaatcaa
    28381 cttgttttat ttttactatc aaaaatagct cattgcctta ctataattaa tatataaatt
    28441 cggtaattaa ttcttaacat gcttttacta ataatctcaa ttgctggccc tataatattg
    28501 cgctagcatt gctttctggt tgtatcagcg atactcaaaa attcttaata caatactcat
    28561 tcgactggta cttatttgta actcagttat attttttcgc ccggtgattc agaagaatgc
    28621 aaaaaacggc taccactcca tcaaaaatac ttgatctcac tgccgcggca tttttacttg
    28681 tcgcctttct gacgggtatt gcgggcgctc ttcagactcc taccctaagt atattcctcg
    28741 cagatgaact gaaagcccgt cctataatgg taggtttttt cttcaccggt agcgctatta
    28801 tgggaattct ggtcagtcaa tttctggcaa ggcactccga taaacaaggc gaccgtaaat
    28861 tactgattct gctatgttgc ttatttggag tgctggcctg cacgcttttt gcgtggaatc
    28921 gcaactactt cattctcctc tcaacgggcg tacttctgag tagttttgct tccaccgcaa
    28981 acccgcaaat gttcgccctc gcccgtgaac acgccgacag aacaggccgt gagacggtca
    29041 tgttcagtac atttttacgt gctcagatct cgcttgcctg ggttatcggg ccaccgctcg
    29101 cttatgaact ggcaatggga
//
LOCUS       DAPOAV010000054        29029 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.054, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000054 DAPOAV010000000
VERSION     DAPOAV010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 29029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29029
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.054"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            118..984
                     /gene="folD"
                     /locus_tag="RN951_002704"
     CDS             118..984
                     /gene="folD"
                     /locus_tag="RN951_002704"
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase
                     FolD"
                     /protein_id="HDX2527682.1"
                     /translation="MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSN
                     PASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLP
                     AGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGL
                     NAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPG
                     DWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTL
                     QACVEYHDPQDE"
     gene            986..1198
                     /gene="ybcJ"
                     /locus_tag="RN951_002705"
     CDS             986..1198
                     /gene="ybcJ"
                     /locus_tag="RN951_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308617.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein YbcJ"
                     /protein_id="HDX2527683.1"
                     /translation="MATFSLGKHPHVELCDLLKLEGWSESGAQAKIAIAEGQVKVDGA
                     VETRKRCKIVAGQTVSFAGHSVQVVA"
     gene            1306..1827
                     /locus_tag="RN951_002706"
     CDS             1306..1827
                     /locus_tag="RN951_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDX2527684.1"
                     /translation="MPTVITHAAVPLCIGLGLGSKVIPPRLLFAGIILAMLPDADVLS
                     FKFGVAYGNVFGHRGFTHSLVFAFVVPLLCVFIGRRWFRAGLIRCWLFLTVSLLSHSL
                     LDSVTTGGKGVGWLWPWSDERFFAPWQVIKVAPFALSRYTTPYGHQVIISELMWVWLP
                     GMLLMGMLWWRRR"
     gene            complement(1863..3248)
                     /gene="cysS"
                     /locus_tag="RN951_002707"
     CDS             complement(1863..3248)
                     /gene="cysS"
                     /locus_tag="RN951_002707"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HDX2527685.1"
                     /translation="MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTF
                     VAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVAMVDRMIAEMHKDFDA
                     LNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDL
                     DQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLG
                     NHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFT
                     VRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAG
                     GEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLG
                     LLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLE
                     DGPQGTTWRRK"
     gene            3422..3916
                     /gene="ppiB"
                     /locus_tag="RN951_002708"
     CDS             3422..3916
                     /gene="ppiB"
                     /locus_tag="RN951_002708"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase B"
                     /protein_id="HDX2527686.1"
                     /translation="MVTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRV
                     INGFMIQGGGFEPGMKQKATKEPIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINV
                     VDNDFLNFSGESLQGWGYCVFAEVVDGMDVVDKIKGVATGRSGMHQDVPKEDVIIESV
                     TVSE"
     gene            3919..4641
                     /gene="lpxH"
                     /locus_tag="RN951_002709"
     CDS             3919..4641
                     /gene="lpxH"
                     /locus_tag="RN951_002709"
                     /EC_number="3.6.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-2,3-diacylglucosamine diphosphatase"
                     /protein_id="HDX2527687.1"
                     /translation="MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFE
                     AWIGDDDPNPLHRKMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKV
                     LELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANS
                     KEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGA
                     WHTEGSMVKVTADDVELIHFPF"
     gene            4759..5268
                     /gene="purE"
                     /locus_tag="RN951_002710"
     CDS             4759..5268
                     /gene="purE"
                     /locus_tag="RN951_002710"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HDX2527688.1"
                     /translation="MSSRNNPARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSA
                     HRTPDKLFSFAESAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVD
                     SLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRKAQTDEVL
                     ENPDPRGAA"
     gene            5265..6332
                     /gene="purK"
                     /locus_tag="RN951_002711"
     CDS             5265..6332
                     /gene="purK"
                     /locus_tag="RN951_002711"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HDX2527689.1"
                     /translation="MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPAAVPFQQS
                     VITAEIERWPETALTRELARHPAFVNRDVFPIIADRLTQKQLFDKLHLPTAPWQLLAE
                     RSEWPAVFDRLGELAIVKRRTGGYDGRGQWRLRANETEQLPAECYGECIVEQGINFSG
                     EVSLVGARGFDGSTVFYPLTHNLHQDGILRTSVAFPQANAQQQAQAEEMLSAIMQELG
                     YVGVMAMECFVTPQGLLINELAPRVHNSGHWTQNGASISQFELHLRAITDLPLPQPVV
                     NNPSVMINLIGSDVNYDWLKLPLVHLHWYDKEVRPGRKVGHLNLTDSDTSRLTATLEA
                     LIPLLPPEYASGVIWAQSKFG"
     gene            complement(6527..7420)
                     /locus_tag="RN951_002712"
     CDS             complement(6527..7420)
                     /locus_tag="RN951_002712"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HDX2527690.1"
                     /translation="MKTLVVALGGNALLQRGEALTAENQYRNIASAVPALARLARSYR
                     LAIVHGNGPQVGLLALQNLAWKEVEPYPLDVLVAESQGMIGYMLAQSLSAQPQMPPVT
                     TVLTRIEVSPDDPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQP
                     RKILDSEAIELLLKEGHVVICSGGGGVPVTDDGAGSEAVIDKDLAAALLAEQINADGL
                     VILTDADAVYENWGTPQQRAIRHATPDELAPFAKADGSMGPKVTAVSGYVRSRGKPAW
                     IGALSRIEETLAGEAGTCISL"
     gene            complement(7417..8232)
                     /locus_tag="RN951_002713"
     CDS             complement(7417..8232)
                     /locus_tag="RN951_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HDX2527691.1"
                     /translation="MTIIHPLLASSSAPNYRQSWRLAGVWRRAINLMTESGELLTLHR
                     QGSGFGPGGWVLRRAQFDALCGGLCGNERPQVVAQGIRLGRFTVKQPQRYCLLRITPP
                     AHPQPLAAAWMQRAEETGLFGPLALAASDPLPAELRQFRHCFQAALNGVKTDWRHWLG
                     KGPGLTPSHDDTLSGMLLAAWYYGALDARSGRPFFACSDNLQLVTTAVSVSYLRYAAQ
                     GYFASPLLHFVHALSCPKRTAVAIDSLLALGHTSGADTLLGFWLGQQLLQGKP"
     gene            complement(8243..9502)
                     /locus_tag="RN951_002714"
     CDS             complement(8243..9502)
                     /locus_tag="RN951_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009029994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HDX2527692.1"
                     /translation="MFTSVAQANAAVIEQIRRARPHWLDVQPASSLISELNEGKTLLH
                     AGPPMRWQEMTGPMKGACVGACLFEGWAKDEAQALAILEQGEVNFIPCHHVNAVGPMG
                     GITSASMPMLVVENVTDGNRAYCNLNEGIGKVMRFGAYGEDVLTRHRWMRDVLMPVLS
                     AALGRMERGIDLTAMMAQGITMGDEFHQRNIASSALLMRALAPQIARLDHDKQHIAEV
                     MDFLSVTDQFFLNLAMAYCKAAMDAGAMIRAGSIVTAMTRNGNMFGIRVSGLGERWFT
                     APVNTPQGLFFTGFSQEQANPDMGDSAITETFGIGGAAMIAAPGVTRFVGAGGMEAAR
                     AVSEEMAEIYLERNMQLQIPSWDFQGACLGLDIRRVVETGITPLINTGIAHKEAGIGQ
                     IGAGTVRAPLACFEQALEALAESMGIG"
     gene            complement(9512..11213)
                     /locus_tag="RN951_002715"
                     /pseudo
     CDS             complement(9512..11213)
                     /locus_tag="RN951_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415051.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
     gene            11530..12579
                     /gene="allD"
                     /locus_tag="RN951_002716"
     CDS             11530..12579
                     /gene="allD"
                     /locus_tag="RN951_002716"
                     /EC_number="1.1.1.154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate dehydrogenase"
                     /protein_id="HDX2527693.1"
                     /translation="MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSH
                     GAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQ
                     QNGVAVVGISRMGHSGAISYFVQQAARAGFIGISMCQSDPMVVPFGGAEIYYGTNPLA
                     FAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGVPTTDPFAVHALL
                     PAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHIVINPNFFSSS
                     ELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRKAAVEGIEIVDDIYQYLISD
                     ALYNTSYETKNPFAQ"
     gene            12601..13836
                     /gene="allC"
                     /locus_tag="RN951_002717"
     CDS             12601..13836
                     /gene="allC"
                     /locus_tag="RN951_002717"
                     /EC_number="3.5.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allantoate deiminase"
                     /protein_id="HDX2527694.1"
                     /translation="MITHFRQAIEETLPWLSSFGADPAGGMTRLLYSPEWLETQQQFK
                     KRMAASGLETRFDEVGNLYGRLNGTEYPQEVVLSGSHIDTVVNGGNLDGQFGALAAWL
                     AIDWLKTQYGAPLRTVEVVAMAEEEGSRFPYVFWGSKNIFGLANPDDVRNICDAKGNS
                     FVDAMKACGFTLPNAPLTPRQDIKAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTV
                     TLNGESNHAGTTPMGYRRDTVYAFSRICHQSVEKAKRMGDPLVLTFGKVEPRPNTVNV
                     VPGKTTFTIDCRHTDAAVLRDFTQQLENDMRAICDEMDIGIDIDLWMDEEPVPMNKEL
                     VATLTELCEREKLNYRVMHSGAGHDAQIFAPRVPTCMIFIPSINGISHNPAERTNITD
                     LAEGVKTLALMLYQLAWQK"
     gene            13847..14632
                     /gene="allE"
                     /locus_tag="RN951_002718"
     CDS             13847..14632
                     /gene="allE"
                     /locus_tag="RN951_002718"
                     /EC_number="3.5.3.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-ureidoglycine aminohydrolase"
                     /protein_id="HDX2527695.1"
                     /translation="MGYLNNVTGYREDLLANRAIVKHGNFALLTPDGLVKNIIPGFEN
                     CDATILSTPKLGASFVDYLVTLHQNGGNQQGFGGEGIETFLYVISGNITAKAEGKTFA
                     LSEGGYLYCPPGSLMTFVNAQAEDSQIFLYKRRYVPVEGYAPWLVSGNASELERIHYE
                     GMDDVILLDFLPKELGFDMNMHILSFAPGASHGYIETHVQEHGAYILSGQGVYNLDNN
                     WIPVKKGDYIFMGAYSLQAGYGVGRGEAFSYIYSKDCNRDVEI"
     gene            complement(14860..16005)
                     /gene="glxK"
                     /locus_tag="RN951_002719"
     CDS             complement(14860..16005)
                     /gene="glxK"
                     /locus_tag="RN951_002719"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 3-kinase"
                     /protein_id="HDX2527696.1"
                     /translation="MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDANYICLPIADG
                     GEGTVDAMVAATGGNIVTLEVCGPMGEKVNAFYGLTGDGKTAVIEMAAASGLMLVAPE
                     KRNPLLASSFGTGELIRHALDNDIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQA
                     LAANGGNLARVASIEMDECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEM
                     VEELEQGLQNYARVLQQQTEINVCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLNAV
                     NLAQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVIGIAGVLGDGVEVVH
                     QYGIDAVFSILPRLAPLAEVLASGETNLFNSARNIACAIKIGQGIKN"
     gene            complement(16027..17328)
                     /locus_tag="RN951_002720"
     CDS             complement(16027..17328)
                     /locus_tag="RN951_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308602.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil/xanthine transporter"
                     /protein_id="HDX2527697.1"
                     /translation="MFNFAVSRESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLL
                     TLTQYAFLATALACFAQAFCGHRRAIMEGPGGLWWGTILTITLGEASRGTPINDIATS
                     LAVGIALSGVLTMLIGFSGLGHRLARLFTPSVMVLFMLMLGAQLTTIFFKGMLGLPFG
                     IADPNFKIQLPPFALSVAVMCLVLAMIIFLPQRFARYGLLVGTITGWLLWYFCFPSSH
                     SLSGELHWQWFPLGSGGALSPGIILTAVITGLVNISNTYGAIRGTDVFYPQQGAGNTR
                     YRRSFVATGFMTLITVPLAVIPFSPFVSSIGLLTQTGDYTRRSFIYGSVICLLVALVP
                     ALTRLFCSIPLPVSSAVMLVSYLPLLFSALVFSQQITFTARNIYRLALPLFVGIFLMA
                     LPPVYLQDLPLTLRPLLSNGLLVGILLAVLMDNLIPWERIE"
     gene            complement(17385..18746)
                     /gene="allB"
                     /locus_tag="RN951_002721"
     CDS             complement(17385..18746)
                     /gene="allB"
                     /locus_tag="RN951_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allantoinase AllB"
                     /protein_id="HDX2527698.1"
                     /translation="MSFDLIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGDAKEVM
                     DASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDR
                     ASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDND
                     FRDVNDWQFFKGAQKLGELGQPVLVHCENALICDELGEEAKREGRVTAHDYVASRPIF
                     TEVEAIRRVLYLAKVAGCRLHVCHVSSPEGVEEVTRARQEGQDVTCESCPHYFVLDTD
                     QFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMKAWGG
                     IAGLQSCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQ
                     PNSSYVLTNDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILK
                     HQQ"
     gene            complement(18806..20260)
                     /locus_tag="RN951_002722"
     CDS             complement(18806..20260)
                     /locus_tag="RN951_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415044.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative allantoin permease"
                     /protein_id="HDX2527699.1"
                     /translation="MEHQRKLFQQRGYSEDLLPKTQSQRTWKTFNYFTLWMGSVHNVP
                     NYVMVGGFFILGLSTFSIMLAIILSAFFIAAVMVLNGAAGSKYGVPFAMILRASYGVR
                     GALFPGLLRGGIAAIMWFGLQCYAGSLACLILIGKIWPGFLTLGGDFTLLGLSLPGLI
                     TFLIFWLVNVGIGFGGGKVLNKFTAILNPCIYIVFGGMAIWAISLVGIGPIFDYIPSG
                     IQKAENGGFLFLVVINAVVAVWAAPAVSASDFTQNAHSFREQALGQTLGLVVAYILFA
                     VAGVCIIAGASIHYGADTWNVLDIVQRWDSLFASFFAVLVILMTTISTNATGNIIPAG
                     YQIAAIAPTKLTYKNGVLIASIISLLICPWKLMENQDSIYLFLDIIGGMLGPVIGVMM
                     AHYFVVMRGQINLDELYTAPGDYKYYDNGFNLTAFSVTLVAVILSLGGKFIHFMEPLS
                     RVSWFVGVIVAFAAYALLKKRTTAEKTGEQKTIG"
     gene            complement(20429..21307)
                     /gene="glxR"
                     /locus_tag="RN951_002723"
     CDS             complement(20429..21307)
                     /gene="glxR"
                     /locus_tag="RN951_002723"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HDX2527700.1"
                     /translation="MKLGFIGLGIMGTPMAINLARAGHQLHVTTIGPVADELLSLGAV
                     SVETARQVTEASDIIFIMVPDTPQVEEVLFGENGCTKASLKGKTIVDMSSISPIETKR
                     FARQVNELGGDYLDAPVSGGEIGAREGTLSIMVGGDEAVFERVKPLFELLGKNITLVG
                     GNGDGQTCKVANQIIVALNIEAVSEALLFASKAGADPVRVRQALMGGFASSRILEVHG
                     ERMIKRTFNPGFKIALHQKDLNLALQSAKALALNLPNTATCQELFNTCAANGGSQLDH
                     SALVQALELMANHKLA"
     gene            complement(21407..22183)
                     /gene="hyi"
                     /locus_tag="RN951_002724"
     CDS             complement(21407..22183)
                     /gene="hyi"
                     /locus_tag="RN951_002724"
                     /EC_number="5.3.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxypyruvate isomerase"
                     /protein_id="HDX2527701.1"
                     /translation="MLRFSANLSMLFGEYDFLARFEKAAQCGFRGVEFMFPYDYDIEE
                     LKHVLASNKLEHTLHNLPAGDWAAGERGIACIPGREEEFRDGVAAAIRYARALGNKKI
                     NCLVGKTPAGFSSEQIHATLVENLRYAANMLMKEDILLLIEPINHFDIPGFHLTGTRQ
                     ALKLIDDVGCCNLKIQYDIYHMQRMEGELTNTMTQWADKIGHLQIADNPHRGEPGTGE
                     INYDYLFKVIENSDYNGWVGCEYKPQTTTEAGLRWMDPYR"
     gene            complement(22196..23977)
                     /gene="gcl"
                     /locus_tag="RN951_002725"
     CDS             complement(22196..23977)
                     /gene="gcl"
                     /locus_tag="RN951_002725"
                     /EC_number="4.1.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate carboligase"
                     /protein_id="HDX2527702.1"
                     /translation="MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIR
                     HILARHVEGASHMAEGYTRATAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITG
                     QAPRARLHKEDFQAVDIEAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLV
                     DLPFDVQVAEIEFDPDMYEPLPVYKPAASRMQIEKAVEMLIQAERPVIVAGGGVINAD
                     AAALLQQFAELTSVPVIPTLMGWGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFG
                     IGNRFANRHTGSVEKYTEGRKIVHIDIEPTQIGRVLCPDLGIVSDAKAALTLLVEVAQ
                     EMQKAGRLPCRKEWVADCQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTT
                     IGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPKRNVVAISGDFDFQ
                     FLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFENINSSEVNGYG
                     VDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERVTNISMGSE
                     LDNVMEFEDIADNAADAPTETCFMHYE"
     gene            complement(24067..24882)
                     /gene="allR"
                     /locus_tag="RN951_002726"
     CDS             complement(24067..24882)
                     /gene="allR"
                     /locus_tag="RN951_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor AllR"
                     /protein_id="HDX2527703.1"
                     /translation="MTEVRRRGRPGQAEPVAQKGAQALERGIAILQYLEKSGGSSSVS
                     DISLNLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHIGLGVFNVGAAYIHNRDVLSVA
                     GPFMRRLMLLSGETVNVAIRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKAL
                     LYPLAEEELMSIILQTGLQQFTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCI
                     ASAIYDDVGSVVAAISISGPSSRLTEDRFVSQGELVRDTARDISTALGLKAHP"
     gene            complement(24960..25442)
                     /gene="allA"
                     /locus_tag="RN951_002727"
     CDS             complement(24960..25442)
                     /gene="allA"
                     /locus_tag="RN951_002727"
                     /EC_number="4.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate lyase"
                     /protein_id="HDX2527704.1"
                     /translation="MKLQVLPLSQEAFSAYGDVIETQQRDFFHINNGLVERYHDLALV
                     EILEQDRTLISINRAQPANLPLTIHELERHPLGTQAFIPMKGEVFVVVVALGDDKPDL
                     STLRAFITNGEQGVNYHRNVWHHPLFAWQRVTDFLTIDRGGSDNCDVESIPEQELCFA
                     "
     gene            25672..26598
                     /gene="allS"
                     /locus_tag="RN951_002728"
     CDS             25672..26598
                     /gene="allS"
                     /locus_tag="RN951_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AllS"
                     /protein_id="HDX2527705.1"
                     /translation="MFDPETLRTFIAVAETGSFSKAAERLCKTTATISYRIKLLEENT
                     GVALFFRTTRSVTLTAAGEHLLSQARDWLSWLESMPSELQQVNDGVERQVNIVINNLL
                     YNPQAVAQLLAWLNERYPFTQFHISRQIYMGVWDSLLYEGFSLAIGVTGTEALANTFS
                     LDPLGSVQWRFVMAADHPLANVEEPLTEAQLRRFPAVNIEDSARTLTKRVAWRLPGQK
                     EIIVPDMETKIAAHLAGVGIGFLPKSLCQSMIDNQQLVSRVIPTMRPPSPLSLAWRKF
                     GSGKAVEDIVTLFTQRRPEISGFLEIFGNPRS"
     gene            26667..27761
                     /gene="mnmH"
                     /locus_tag="RN951_002729"
     CDS             26667..27761
                     /gene="mnmH"
                     /locus_tag="RN951_002729"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HDX2527706.1"
                     /translation="MQERHTEQDYRALLIADTPIIDVRAPIEFEHGAMPAAINLPLMN
                     NDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQ
                     RSHIVQSWLHAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQ
                     QQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDES
                     RMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQ
                     EYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDGHLAWLVPLLEEYYD
                     PMYRYQLEKKAEKVVFRGEWAEVAEWVKAR"
     gene            27877..28242
                     /locus_tag="RN951_002730"
                     /pseudo
     CDS             27877..28242
                     /locus_tag="RN951_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014543172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(28763..28936)
                     /locus_tag="RN951_002731"
     CDS             complement(28763..28936)
                     /locus_tag="RN951_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527707.1"
                     /translation="MAKIVSKNDPDTKKVWCKYGKIPGQGDGVNLFFVGEINVTHYFI
                     TNIGAGLPDACAE"
BASE COUNT         7179 a         7831 c         7192 g         6827 t
ORIGIN      
        1 cttcgcaaga ggtcgcttca cgcgataaat ctgaaacgaa acctgacagc gcgccccgct
       61 tctgacaaaa taggcgcatc cccttcgatc tacgtaacag atggaatcct ctctctgatg
      121 gcagcaaaga ttattgacgg taaaacgatt gcgcagcagg tgcgctctga agttgctcaa
      181 aaagttcagg cgcgtattgc agccggactg cgggcaccag gactggccgt tgtgctggtg
      241 ggtagtaacc ctgcatcgca aatttatgtc gcaagcaaac gcaaggcttg tgaagaagtc
      301 gggttcgtct cccgctctta tgacctcccg gaaaccacca gcgaagcgga gctgctggag
      361 cttatcgata cgctgaatgc cgacaacacc atcgatggca ttctggttca actgccgtta
      421 ccggcgggta ttgataacgt caaagtgctg gaacgtattc atccggacaa agacgtggac
      481 ggtttccatc cttacaacgt cggtcgtctg tgccagcgcg cgccgcgtct gcgtccctgc
      541 accccgcgcg gtatcgtcac gctgcttgag cgttacaaca ttgatacctt cggcctcaac
      601 gccgtggtga ttggcgcatc gaatatcgtt ggccgcccga tgagcatgga actgctgctg
      661 gcaggttgca ccactacagt gactcaccgc ttcactaaaa atctgcgtca tcacgtagaa
      721 aatgccgatc tattgatcgt tgccgttggc aagccaggct ttattcccgg tgactggatc
      781 aaagaaggcg caattgtgat tgatgtcggc atcaaccgtc tggaaaatgg caaagttgtg
      841 ggcgacgtcg tgtttgaaga cgcggctaaa cgcgcctcat acattacgcc tgttcccggc
      901 ggcgttggcc cgatgacggt tgccacgctg attgaaaaca cgctacaggc gtgcgttgaa
      961 tatcatgatc cacaggatga gtaacatggc gacattttct ttaggtaaac atccgcacgt
     1021 tgagctgtgc gacttgctga aactggaagg ctggagcgaa agcggcgcgc aggcgaaaat
     1081 cgcgattgcc gaaggccagg tgaaagtcga cggtgcggtt gaaacgcgca aacgctgcaa
     1141 aatcgtcgcc ggtcagacag tgagttttgc aggtcacagc gtacaggttg ttgcctgatc
     1201 cctttcccgg cctgtatcaa caggccggtt ctcttttcag acttttgccc tctacgcccc
     1261 gttcatccat gctgatagca tcgacatttt gccgaagcga ccatcatgcc aaccgttatt
     1321 acgcacgccg ccgttcccct atgcattggt ttagggttgg gttcgaaagt catccctccg
     1381 cgtctgttat ttgccggaat catcctggcg atgctgcccg acgccgacgt attgtcgttt
     1441 aaatttggcg ttgcttacgg caatgttttt ggtcatcgcg ggtttaccca ttcgctggtg
     1501 tttgcgtttg ttgtcccgct gttatgtgtg tttattggac gccgatggtt cagggctggg
     1561 ctgattcgct gctggctgtt tttaaccgtc tcgttgctat cgcacagctt gctggattcg
     1621 gtaaccactg gcggtaaagg cgttggctgg ctgtggccgt ggtcagatga acgctttttc
     1681 gctccctggc aggtgataaa agtcgcgccg tttgcattgt ctcgttacac cacgccgtac
     1741 gggcatcagg tgattatttc tgaattgatg tgggtgtggt tgccggggat gctactgatg
     1801 ggaatgttgt ggtggcgcag acgataaccg gatgcgaaaa ctcgcatccg gcaatagcgc
     1861 aattacttac gacgccaggt ggtcccttgc gggccatctt ccagcacgat ccccatctcg
     1921 ttaagacgat cacgcgccgc atccgccgcc gcccagtctt tcgctttacg ggcatccaga
     1981 cgctgttgaa ttaacgcttc aatctcagcc acttcgctgt cgtctgcctg cgcgccgctt
     2041 tgcaggaacg cttccggttc ttgctccagc aggcccaata cagcggaaag tttacgcagg
     2101 tgagatgcca ttgcattcgc cgctgccata tcttctgctt tcagacggtt tacttcacgc
     2161 gccatatcaa acagtacgga ataggcttcc ggggtgttga aatcgtcgtc catcgcttca
     2221 ataaagcgcg cttcaaacgc ttcgccaccg gcaggcgcaa cggttttatc tgtgccgcgc
     2281 agcgcagtgt agagacgctc cagcgccgca cgcgcctgct tcaggttctc ttcgctgtag
     2341 ttcaactggc tgcgatagtg gcccgacatc aggaagtaac gcacggtttc cgcgtcgtag
     2401 tatttcagca catcgcgcac ggtaaagaag ttacccagcg atttggacat cttctcgcgg
     2461 tcaaccatca ccatccccga gtgcatccag tagttcacat actgaccatc atgggcacag
     2521 gtggactgcg cgatttcgtt ttcgtggtgc gggaacatca ggtctgaacc gccgccgtgg
     2581 atatcaaagt ggttacccag ctgcttgcag ttcattgccg aacattcaat gtgccagcca
     2641 ggacgacccg cgccccacgg agacggccag ctcggttcgc cctctttcga catcttccac
     2701 agaacgaagt ccattgggtt gcgtttgtcg tcgaccacgt caacgcgcgc gcctgcctgc
     2761 agctggtcga gatcctgacg cgacagcacg ccataagttg gatcggtcgg gacgtcgaac
     2821 atcacgtcgc cgttgtccgc cacataagcg tgacctttgg cgatcagttg ttcagtgagt
     2881 tcaataattt ctgcgatatg gtgcgtcgcg cgcggctcca tatccgggcg cagaatgttc
     2941 aaagcatcaa aatctttgtg catttcggcg atcatgcgat ccaccatcgc cacaaagctt
     3001 tcgccatttt cattggcgcg tttgatgatt ttgtcgtcga tatcggtaat gttgcgcaca
     3061 tacttcagtt tatagccgag gaaacgcaga tagcgcgcaa ccacgtcaaa agcaacaaag
     3121 gtacgcccgt gaccgatatg acagagatcg taaacggtga ttccacacac gtacatgccg
     3181 acttccccgg cgtgaatagg cttaaattcc tctttttggc gtgtcagagt attgaagatt
     3241 tttagcatcg aagattccgt ttagacatgt gtgggtaatt gagttgcgta taatacccat
     3301 atttcccgcg cgaatcagca tacattgcgt gatgatccga tcgtgcggtt atgctataac
     3361 accaccctat atatgacccg aactgggttg aagcaccaat caaacggaac aggatgcaaa
     3421 aatggttact ttccacacca atcacggcga tattgtcatc aaaacttttg acgataaagc
     3481 acctgaaaca gttaaaaact tcctggacta ctgccgcgaa ggtttttaca acaacaccat
     3541 tttccaccgt gttatcaacg gctttatgat tcagggcggc ggttttgaac cgggcatgaa
     3601 acaaaaagcc accaaagaac cgatcaaaaa cgaagccaac aacggcctga aaaatacccg
     3661 tggtacgctg gcaatggcac gtactcaggc tccgcactct gcaactgcac agttcttcat
     3721 caacgtggtt gataacgact tcctgaactt ctctggcgaa agcctgcaag gttggggcta
     3781 ctgcgtgttt gctgaagtgg ttgacggcat ggacgtggta gacaaaatca aaggtgttgc
     3841 aaccggtcgt agcggtatgc accaggacgt gccaaaagaa gacgttatca ttgaaagcgt
     3901 gaccgttagc gagtaatcgt ggcgacactc tttattgcag atcttcatct ctgcgtggaa
     3961 gaaccggcga tcaccgccgg ttttctgcgt tttttagcgg gggaagcccg caaggccgac
     4021 gcgctgtata ttcttggcga tctgtttgaa gcatggattg gcgacgacga tcccaaccca
     4081 ctccatcgca agatggcggc ggcgatcaaa gcggtgtccg attccggcgt tccctgttat
     4141 ttcattcatg gcaaccgtga ttttctgctc ggcaaacgct ttgcccgtga aagtggcatg
     4201 acgttattgc cggaagaaaa ggtgctcgaa ctttatggtc gccgggtgtt gattatgcat
     4261 ggcgacacgc tgtgcaccga tgacgcgggt tatcaggctt ttcgcgccaa ggtccacaaa
     4321 ccctggctgc agacgctatt cctcgccctg ccgttgtttg tgcgcaaacg cattgccgcg
     4381 cgaatgcgcg cgaacagcaa agaagccaac agcagtaaat cgctggcgat catggacgtt
     4441 aaccaaaacg cggtggtcag tgcgatggaa aaacatcagg tgcaatggct gatccacggg
     4501 catacccatc gcccggcggt gcatgaactt atcgccaatc agcaacctgc ttttcgcgtg
     4561 gtactgggtg cctggcatac ggaaggttca atggtgaaag tcacggcgga tgacgttgag
     4621 ctgattcatt ttccgtttta aaaaacccgc aactttgctg atttcacagc cacgcaaccg
     4681 ttttccttgc tctctttccg tgctattctc tgtgccctct aaagccgaga gttgtgcacc
     4741 acaggagttt taagacgcat gtcttcccgc aataatccgg cgcgtgtcgc catcgtgatg
     4801 gggtccaaaa gcgactgggc taccatgcag ttcgccgccg aaatcttcga aatcctgaat
     4861 gtcccgcacc acgttgaagt ggtttctgct caccgcaccc ccgataaact gttcagcttc
     4921 gccgaaagcg ccgaagagaa cggttatcag gtgattattg cgggcgcagg cggcgcagcg
     4981 catctgccag gcatgattgc cgccaaaacg ctggtgccgg tgctgggcgt gccagtacag
     5041 agcgccgcac tgagcggtgt cgatagcctc tactccatcg tacaaatgcc gcgcggcatt
     5101 ccggtgggta cgctggcgat tggtaaagct ggcgcggcaa acgcggcgtt actggcagca
     5161 caaattcttg cgactcatga taaagaactg caccagcgtc tgaatgactg gcgcaaagcc
     5221 cagaccgacg aagtgctgga aaacccggac ccgcgaggtg cggcatgaaa caggtttgcg
     5281 tcctcggtaa cgggcagtta ggccgtatgc tgcgtcaggc aggcgaaccg ttaggcattg
     5341 ctgtctggcc agtcgggctg gacgctgaac cggcggcggt gccttttcaa caaagcgtga
     5401 ttaccgctga gatagaacgc tggccggaaa ccgcattaac ccgcgagctg gcgcgccatc
     5461 cggcctttgt gaaccgcgat gtgttcccga ttattgctga ccgtctgact cagaagcagc
     5521 ttttcgataa gctccacctg ccgactgcac cgtggcagtt acttgccgaa cgcagcgagt
     5581 ggcctgcggt gtttgatcgt ttaggtgagc tggcgattgt taagcgtcgc actggtggtt
     5641 atgacggtcg cggtcaatgg cgtttacgcg caaatgaaac cgaacagtta ccggcagagt
     5701 gttacggcga atgtattgtc gagcagggca ttaacttctc tggtgaagtg tcgctggttg
     5761 gcgcgcgcgg ctttgatggc agcaccgtgt tttatccgct gacgcataac ctgcatcagg
     5821 acggtatttt gcgcaccagc gtcgcttttc cgcaggccaa cgcacagcag caggcgcaag
     5881 ccgaagagat gctgtcggcg attatgcagg agctgggcta tgtgggcgtg atggcgatgg
     5941 agtgttttgt taccccgcaa ggtctgttga tcaacgaact ggcaccgcgt gtgcataaca
     6001 gcggtcactg gacacaaaac ggtgccagca tcagccagtt tgagctgcat ctgcgggcga
     6061 ttaccgatct gccgttaccg caaccagtgg tgaataatcc gtcggtgatg atcaatctga
     6121 ttggtagcga tgtgaattat gactggctga aactgccgct ggtgcatctg cactggtacg
     6181 acaaagaagt ccgtccgggg cgtaaagtgg ggcatctgaa tttgaccgac agcgacacat
     6241 cgcgtctgac tgcgacgctg gaagccttaa tcccgctgct gccgccggaa tatgccagcg
     6301 gcgtgatttg ggcgcaaagt aagttcggtt aactggtgct ctattcttgc cggatgcggc
     6361 gtaaacgcct tatccggcct accgatccgg tacccattgt aggcctgata agatgcgtca
     6421 agcatcgcat caggcattgt gcaccaattg ccggatgcgg caccggttgt aggcctgata
     6481 agacgcgtca agcgtcgcat caggcacaaa tgtctaatgc ctacgactac agcgaaatac
     6541 aggtccccgc ttcgcccgcc agcgtctctt caattcgcga taacgcccca atccacgcgg
     6601 gtttaccacg gcttctgaca taaccactca ccgccgttac cttcggcccc atcgaaccat
     6661 cggctttggc aaatggcgct aactcatccg gtgtggcatg gcgaatggca cgttgctgcg
     6721 gcgttcccca gttttcatat accgcatcag catcggtgag gatcaccagt ccatctgcat
     6781 taatctgctc ggcgagcaac gcagcggcga gatctttatc aatcactgct tcactccctg
     6841 ctccgtcatc cgtcacaggc acaccgccgc cgccactgca aatcaccaca tgcccctctt
     6901 tgagcaacaa ctcgatggct tcgctgtcga gaattttacg cggttgcgga gacgccacca
     6961 cccggcgcaa atatttacca tcacgtttca tctgccagcc gtaagccgct tccagtgcct
     7021 cttgttcttc tggctgataa accggaccaa taaatttctc tggctgcaaa aacgccggat
     7081 catcaggcga aacctcaatg cgcgtcagca ccgtcgtcac gggcggcatc tgcggctgtg
     7141 cgctcaaact ctgcgccagc atatagccaa tcatcccctg gctttccgca accagcacat
     7201 ccagcggata cggttctacc tctttccacg ccagattctg caatgccagc agccccacct
     7261 gcggcccgtt gccgtgaaca atcgccaacc gataagaacg ggccaggcgt gccagcgcgg
     7321 gtacagcact ggcgatattg cgatattgat tttctgccgt cagcgcctca ccgcgctgga
     7381 gtaaggcgtt gcccccaaga gccacaacca gtgttttcat ggttttcctt gtaataattg
     7441 ttggccaagc cagaacccca gcagcgtatc tgcccctgac gtatgcccca gcgccagcag
     7501 cgaatcaatc gcaacagcgg tacgtttcgg gcaactcaga gcatgaacaa agtgcaggag
     7561 tggcgaggcg aaatatcctt gcgcggcata acgtaaataa ctgacgctca ccgctgtggt
     7621 aacgagttgc agattgtcgg aacaggcaaa aaacggacga ccggagcgcg catctaaagc
     7681 gccataatac caggccgcca gcagcattcc gctcagcgtg tcatcatgac tcggcgttaa
     7741 tccggggcct ttacccagcc agtgccgcca gtcggtctta acgccattga gcgcggcctg
     7801 aaaacagtga cgaaactggc gtaactcagc aggcagcgga tcgcttgccg ccaacgccag
     7861 tggcccgaaa agcccggttt cctccgcgcg ttgcatccat gcagctgcaa gtggttgagg
     7921 atgcgcaggc ggcgtaatac gcagcaaaca ataacgctgt ggctgtttaa ccgtgaaacg
     7981 cccgaggcga atcccttgag ccacaacctg tggtcgttca ttgccgcata atccaccgca
     8041 taacgcatcg aattgcgcac ggcgaagcac ccatcctccg gggccgaaac cactaccctg
     8101 acgatgcaac gttaacagtt cgccgctttc cgtcatcagg ttaatcgccc gccgccacac
     8161 tcccgctaac cgccaggact ggcgataatt cggtgcgcta ctactggcaa gcagaggatg
     8221 gatgatcgtc attgcgcgtt cctcaaccaa tacccatgct ttcagccagt gcttccagcg
     8281 cctgttcaaa gcacgccagc ggtgcccgca cggtgcctgc gccaatctgc ccgatccccg
     8341 cctctttatg ggcgataccg gtattgatga gtggcgtaat gccggtttct accacgcgac
     8401 gaatgtccag ccccaggcac gcgccctgaa aatcccagct tgggatctgc aactgcatat
     8461 tgcgttcaag gtaaatttcc gccatctctt cagataccgc tcttgccgct tccatgccac
     8521 ccgcaccgac aaagcgcgtt acgccaggcg ctgcgatcat tgccgcacct ccgataccaa
     8581 aggtttcggt aatcgcgcta tcgcccatat ccgggttcgc ctgctcctgc gagaagccgg
     8641 tgaaaaacag accttgcgga gtgtttacag gcgcagtaaa ccagcgttcg cccagcccgc
     8701 ttacccgaat cccgaacata ttgccgttgc gggtcattgc cgtgacgatg ctgcctgcgc
     8761 ggatcatcgc gccagcatcc atcgccgcct tgcagtaagc catcgcgagg ttgaggaaga
     8821 actgatcggt cacgctgagg aaatccatca cttcggcgat gtgctgttta tcatgatcga
     8881 ggcgagcaat ttgtggggcc agcgcacgca ttaacagtgc agaggaagca atattgcgtt
     8941 gatggaactc atcgcccatc gtaatgccct gcgccatcat cgccgtgaga tcgataccgc
     9001 gctccatgcg ccccagcgcc gcgcttaata ctggcattaa cacatcgcgc atccagcgat
     9061 ggcgagtcag gacatcttcg ccgtaagcgc caaaacgcat cactttgccg ataccttcgt
     9121 tgagattgca gtacgcccgg ttgccgtcgg tcacgttctc aaccaccagc atcggcatac
     9181 tggcagaagt aataccgccc attggcccga cggcattcac atggtgacaa ggaatgaagt
     9241 tcacttcccc ctgctccagt attgccagcg cctgcgcttc atctttcgcc caaccttcga
     9301 acagacatgc gcccacgcac gcccctttca tgggtccggt catctcctgc cagcgcattg
     9361 gcggcccggc gtgaagcagt gttttgccct cgtttagttc gctgataagt gaagaagccg
     9421 gttgcacatc cagccagtgt ggacgagcgc gacgaatttg ttcgataacc gcagcattgg
     9481 cttgcgccac tgatgtaaac atgggaaccc cttattgcaa acgttctaat aaacgagcca
     9541 gttttttatt gccaccggcg actggcgacc attggtaatg cacaaccggt ttgctggcgc
     9601 tttgtagctc cagcgcaaag ctgcgtaatc cgatgttaat cacggcgacg ttttccagta
     9661 atgacggtgt gtgttgctgt gcggcaggcg agagcggatg aattaacgct gccgccagca
     9721 aggtggcttc cggtagcgaa ctcacgaccg caatccccgc atcttccagc gtggcgattt
     9781 gctgcgagcg gcattgcggg tcacgttcag tgcctgtcac cgtggcaatg gcatacagtg
     9841 gttgattatc taaacgcgcg gcacaggctt tttgccaggc gctcaccagc gaggcggcag
     9901 gatcggcggt cgcaccgaag ccaatcacga catcaagcag caacacgcgc acttgcggtt
     9961 tagcgccgag atcggcaatt aactggttgc gtaaggttgg gtcgatcatc ggatggggac
    10021 gcccgacggt gtagaaatca tcgccgaggt caataatctg gtggctatcg gcgtccagca
    10081 tcatgccatg ttgatgggta tcgtcggctt ccacgccaag gtgtccggca agtaatcccg
    10141 ccgcttcggc agccagcgta ccgccggtat acaaaccgca aataaatccg ctgctgacag
    10201 gcgctattgc gttacgttgc gccgtgacgc gtgaaagcag gcaagccagg cgtgcggcct
    10261 catccagcga ggaggcaaac caggcgtgcg gcctcatcca gcgaggaggc aaaccagaca
    10321 ttctcgtcgc gggccaccgc cggggtataa cctaaaaaca gcgccaccgt cggtttgccg
    10381 gttgctttca tggcattaac aattttcaga cgcacagctt cggcaggtgg ttttgaaaca
    10441 aatgccagca cttcgctttt ctcgtctgca ctgagcattt ccagcgctgt tagcgcactg
    10501 atgccgccca cttcacggct gaggtcgcgc ccgccaaggc caatcgcgtg agtaattccc
    10561 tcccctgcca gcgcaatctg cgaacacagc tcctgaatcc cggtaccgga agcgccaatg
    10621 acgccaatat tgccttccgg catcacgtta gcaaaagcca gcggtgtgcc ggcaatcatc
    10681 gacgtaccgc agtccggccc catcaccagc aagccttttt cccgcgcgcg ggttttaagt
    10741 tggatttcat cttccagcgt gacgttatcg gagaacatca tcacgttgag gttgcgatcc
    10801 agcgcctggt ttgccagctc cgccgcatac tcgccagcca ctgaaatcag cgccagattg
    10861 gcatcgggta atttctgaca ggcactgtcc cagcgacgca cctgcatcaa cgcctggctg
    10921 ctgcctgacc cctgcgccag ttgttttagc gcctcttcaa gctgctgcat aatcgcctgc
    10981 gcgatccccg catccgccgc ttcgctacga attgccacgc aaatatcgtt cggcgtggcg
    11041 ttattaaaat cgtcatgcca gaaacctgtg gtatctaata acgctttatt ggcgggcgta
    11101 cccatcatta cggaaacatc atcaacattt tctgattcgc tgagttttcg tgaaataatc
    11161 attaaactga ccgaatcctg aaaacaccct tttttaataa aggcgtggat cataacaact
    11221 ccttaaaaat tgcacccatg gcaattgcac gagcagtgtt aatgtggcga ttacggtatc
    11281 gatgacaacg agtaaataag gtgatgaata tcacacagga attattaaca aaagaattca
    11341 aataaccacc aggctattac tcattatttt ttaataagcg ttgttgtttt aaaaatcagg
    11401 ttaaaagtga gcggattatc aaataaattc taactatatt tttttgcctg tctggatcac
    11461 ataatccaga tattttccct gtatgttaat tgcagtcatg cttcacaccg tcgttaaaaa
    11521 ggaagacaga tgaaaatcag tcgggaaaca ctccaccagc taattgagaa taaactctgc
    11581 caggctgggt taaaacgtga gcacgctgca accgtggctg aagtattggt ttacgccgat
    11641 gccagaggga tccactctca tggcgcggtg cgcgtggaat actacgcgga acgcatttca
    11701 aaaggcggca ccaaccgcga accggagttt cgtcttgagg aaaccgggcc gtgctcggca
    11761 attttacatg ccgacaatgc cgccggacag gtcgcggcga aaatgggtat ggaacatgcc
    11821 atcaaaaccg cccagcaaaa tggcgttgcg gtggtcggta tcagccggat gggtcacagc
    11881 ggcgcaatct cttattttgt gcagcaggca gcccgcgccg gattcattgg catttcgatg
    11941 tgccagtccg atccaatggt ggtgccgttt ggcggcgcgg aaatttacta cggtactaac
    12001 cccctggcct ttgccgcgcc gggagaaggc gacgagatcc ttacctttga tatggcgact
    12061 accgtacagg catggggaaa agtgctcgac gcccgctcgc gtaatatgtc tatcccggat
    12121 acctgggcgg tcgataaaaa cggtgtacca acaaccgatc cgttcgcggt acatgctctg
    12181 ctccccgccg ccgggccaaa agggtatggc ctgatgatga tgattgacgt cctctcaggc
    12241 gtcttactcg gcttaccgtt cgggcgacag gttagttcga tgtatgacga tttacacgca
    12301 gggcgtaatt tggggcaatt acatatagtt attaatccga actttttctc ctccagcgaa
    12361 ttattccgtc aacatcttag ccagaccatg cgcgaattaa atgccattac ccccgcgccc
    12421 ggttttaatc aggtttatta tcccggacag gatcaggata ttaaacaacg caaagccgcc
    12481 gtcgaaggca tcgaaattgt tgatgatatt taccagtatt taatttccga cgcgctttat
    12541 aacacgtcat acgaaacgaa aaatcccttt gcgcaataat tattgagaca ggactttctt
    12601 atgattacac atttccgtca agctatagaa gaaacgctgc cctggctttc ctcttttggc
    12661 gctgacccag cgggtgggat gacccgttta ctttattcgc cggaatggct ggaaacccag
    12721 cagcaattta aaaaaagaat ggcagcaagc gggctggaaa cacgtttcga tgaagtgggg
    12781 aatttatacg gtcgcctgaa tggcaccgaa tatccacagg aagtggttct gagcggttcg
    12841 catatcgata ccgtggttaa cggcggtaac cttgacgggc aattcggcgc gctggcggcg
    12901 tggctggcaa ttgactggct gaaaacgcaa tacggcgcgc cgctacgtac ggtcgaagtg
    12961 gtggcgatgg cagaagaaga aggcagccgc ttcccgtatg tcttctgggg cagtaaaaat
    13021 atttttgggc tggcgaatcc tgacgacgtg cggaatatct gtgatgccaa aggaaatagt
    13081 tttgtcgatg cgatgaaggc ttgcggattt actcttccga acgccccact aactccgcgt
    13141 caggatatta aagcctttgt tgaactgcat attgaacagg gctgtgtgct ggaaagtaat
    13201 gggcaatcaa ttggcgtggt gaatgcaatt gtcgggcagc gtcgttatac ggtaacgctg
    13261 aacggcgaat caaaccatgc aggcaccacg ccgatgggtt atcgtcgtga tacagtttac
    13321 gctttcagtc gcatttgcca tcagtcggtc gaaaaagcga aaaggatggg cgatccgctg
    13381 gttctgacct ttggcaaagt agagccgcgc ccgaatacgg taaatgtggt gccgggtaaa
    13441 accacgttca ccattgattg tcgtcatacc gacgctgccg tgctgcgcga tttcacccaa
    13501 cagttagaaa acgacatgcg ggcgatttgc gatgaaatgg acattggtat tgatatcgat
    13561 ttatggatgg acgaagaacc cgtgccgatg aataaggagc tggtcgccac cctgacagaa
    13621 ttgtgtgaaa gagaaaaact gaattaccgg gtgatgcaca gtggtgccgg gcacgacgcg
    13681 caaattttcg cgcctcgcgt accaacctgc atgattttta tccccagcat caacgggatc
    13741 agccataacc cggcggaacg caccaatatt accgaccttg ccgaaggggt caaaacgttg
    13801 gcactcatgc tttatcaact tgcctggcag aaataaggag tcataaatgg gatatttaaa
    13861 taacgtcacc ggttaccgcg aagatttact ggctaaccgt gcgattgtta aacacggtaa
    13921 tttcgcactg ttaaccccgg atggtctggt aaaaaatatt attccgggct ttgaaaattg
    13981 tgacgcgaca atcctctcca cgccaaagct gggtgcctct tttgttgatt atctggtcac
    14041 actgcatcaa aacggtggca accaacaggg cttcggtggc gaaggcattg aaacgttcct
    14101 gtatgtgatc tctggaaata tcactgccaa agccgaaggc aaaacatttg ccttaagcga
    14161 aggtggctat ctttattgcc cgccaggctc cttaatgacg tttgttaacg cccaggccga
    14221 agacagccaa atctttttat ataagcgccg ctatgttccg gtagaaggct atgcaccgtg
    14281 gctggtttct ggcaatgcca gcgaactgga acgcattcat tatgaaggca tggacgatgt
    14341 tattctgctg gattttctgc ccaaagagtt aggttttgat atgaacatgc atatcctctc
    14401 ttttgcacca ggtgccagcc acggttatat cgaaacacac gttcaggaac acggtgccta
    14461 tattctttcc ggtcaggggg tttataacct cgacaataac tggatcccgg tgaaaaaagg
    14521 cgattacatc tttatgggcg cttattcttt acaggctggt tatggtgtag ggcgtggtga
    14581 agcgttcagc tatatttact cgaaagattg taaccgcgac gtagagattt aagtcatacc
    14641 actcgcctga ttatttttag ctatgttgga ttttgccacg gtttataccg tggctttttt
    14701 tgtaacattg cctgatgcgc ttcgcttatc aggcctacat gatctctgca atatatagaa
    14761 tttgcgcgat tttcaggaag gatatggtac tcatgccgca tccggcatga gtactgcact
    14821 cttatgcgat ataaatcgca tccgctttaa aggtaagggt tagtttttaa ttccctgacc
    14881 tattttaatg gcgcaggcaa tatttcgcgc gctgttgaag agattggttt caccgctggc
    14941 gagcacttcg gctaaaggtg ccagacgagg caaaatgctg aataccgcgt caatgccgta
    15001 ctggtgcacc acttccacgc catcacccaa tacgccagca atcccaatca ccggtacatt
    15061 aaactgcttc gccaccgacg ccacacccag cggcgcttta ccgcctgccg tttgcgagtc
    15121 gatgcgccct tccccggtaa tcaccagtgc tgcgccctgc actgcctgcg caagattgac
    15181 cgcattcaac acaatttcaa tgcccggttt aatatccgca ttgagaaata ccgccgccgc
    15241 aatacccata ccgcccgcag cgccgccgcc cgccatctgg cagacattaa tttcagtttg
    15301 ctgttgtaaa acacgggcgt aattttgcag cccctgttca agttcttcga ccatctccgg
    15361 cgttgcccct ttttgcgggc caaacaccgc cgccgcgccg cgtgccccta ccagcgggtt
    15421 atcaacgtca catgctactt caatatggca attcgccaga cgcggatcgc attcatccat
    15481 ctcaatgctt gccacgcgcg ctaaattacc accgtttgcc gccagcgcct gaccgtcggc
    15541 atcaaggaaa cgcacaccga gcgcctgcgc catgcccata ccgccgtcga ccgtcgcact
    15601 gccgccaatg ccgagaataa tatggcgaat gtcgttatcc agcgcatgac gaattaactc
    15661 ccccgtacca aaactggagg ccagcaacgg attacgcttt tcaggcgcga ccagcatcag
    15721 gccacttgct gccgccatct caatcaccgc cgttttcccg tcgccggtaa ggccataaaa
    15781 agcattcact ttttcgccca tcggcccgca gacttcaagc gtcacgatgt tgccgcccgt
    15841 cgcggcgacc atcgcatcca ccgtcccttc gccgccatcc gctatcggca aacagatata
    15901 gttcgcatcg ggaaagaggg tcgaaaaccc ggctttaatt gcctgacaac atttttctgc
    15961 acttaagctc tctttaaaag agtctggcgc aatgacaatc ttcattatca atcctttttc
    16021 aacaaattat tcgatgcgtt cccacggaat aaggttatcc ataagaacag ccagtaaaat
    16081 cccgaccaat aagccgttac tgagcagagg acgaagcgtt aatggaaggt cttgcagata
    16141 cacaggcggt aatgccatta aaaatatgcc gacaaataac ggcaatgcga gtcgataaat
    16201 attgcgagcg gtaaacgtta tttgctggct aaacaccagc gcggaaaaga gtaaaggcag
    16261 ataagaaacc agcatgaccg cactactcac gggtaaaggg atactgcaaa acagtcgcgt
    16321 gagtgcagga accagcgcca ccagcaggca aataacgctg ccataaataa acgaacgccg
    16381 cgtgtaatcg ccagtctggg ttaataaacc aatggatgaa acaaacggtg aaaatggaat
    16441 taccgccagc ggtacggtta tcagcgtcat aaatccggtc gccacaaagc tacgacgata
    16501 acgcgtattc cctgcgccct gctgcggata aaaaacatcc gtgccccgaa tcgcaccgta
    16561 ggtattgctg atatttacca gacctgtaat caccgccgtc agaataattc ccggcgacaa
    16621 agcaccgcca ctgccgagcg ggaaccactg ccagtgcaac tcaccggaga gcgagtgcga
    16681 agaaggaaag caaaagtacc acaacaacca gccggttatg gtgccgacca gcaggccata
    16741 acgggcaaaa cgttgcggca ggaagataat catcgccagt accaggcaca tcaccgccac
    16801 cgagagcgcg aacggcggta actgaatttt aaaattcggg tcggctatgc caaacggcag
    16861 cccgagcata cctttgaaaa agatagtggt cagctgcgcg cccagcatca acataaacaa
    16921 gaccatcacc gacggcgtaa ataaccgtgc caggcgatgg cctaatccgc taaaaccaat
    16981 caacatcgtc agcacgccgg agagtgcaat ccccactgcc aggctggtgg cgatatcgtt
    17041 gatcggtgtc ccgcgcgatg cttcaccaag ggtgatagta aggatggttc cccaccacag
    17101 gccacctggc ccttccataa tagcgcgacg atgaccgcaa aacgcctgag cgaagcaggc
    17161 cagtgcggta gcaagaaaag catattgcgt gagcgtaagc aggctacttt gcggcaactg
    17221 aaaagcagaa agtagcgtag gaggaaccac aaccgtgttg caaaaaataa agaaaaacca
    17281 ctgaaatcct gataacaggc tttcgcggct gactgcaaaa ttgaacataa acacacctta
    17341 accggagaat gcccgccgca aggacgggca ttgcaggggc cagattactg ctgatgttta
    17401 aggataaatt gacctttcgg cgcaacaggg aagccctgtt caatgtcgta aatcacatca
    17461 ccacgtaaga tggttttcgt gatacgcgcg ccaatggtac ggccaacata cgggctgact
    17521 ttgtggcgat attccagatc gtcattggta agaacatagc tgctattcgg ctgaatgaag
    17581 acgaagtcgg catcttttcc tggggcgata cggccttttt gctgcagacc gaaaatatct
    17641 gctgcgttag tcgccattaa tttgccgaac attggcagag acataccgcg tttctgtacc
    17701 gcttcatcga acatcacgtc catgcagctt tgcagaccgg cgataccgcc ccatgctttc
    17761 atgatgttac cggctttcat ttccggcggg catggagagt ggtcggaaac caggcagtcg
    17821 atttcaccgt taaacagttt ttcccacatg cctttctggt tttccagatc gcggatcggc
    17881 ggtgaacact tcgccagagt accgatttct tcgaactgat cggtatccag tacaaagtaa
    17941 tgcgggcagg attcacaagt aacgtcctga ccttcctgac gtgcacgagt cacttcctca
    18001 acaccttccg ggctgctgac gtggcaaacg tgcagacggc aaccagcaac tttcgccaga
    18061 tacagtacgc ggcgaattgc ttccacttcg gtaaatatcg gacgcgaagc cacatagtca
    18121 tgagcggtta cgcgaccttc acgcttcgct tcttcgccca gttcgtcaca aatcagcgcg
    18181 ttttcgcagt gcaccagcac cggctgaccc agttcgccca gcttctgcgc acctttgaag
    18241 aactgccagt cgtttacatc acggaagtcg ttgtcgatac cgcgatcgcc acaggtcgca
    18301 acgaagcatt tgaagccgac aacgcccact tcatccagct catgcagacg gtcgatgttg
    18361 taagacacca ggccaccgag ttgtgccgca tcaatagtca gcttgccttt agcggcatcg
    18421 aacttcagtt caattgaagc gcggtcaacc gttgcaggca gctggttgag cggcatttcg
    18481 atcatggtgg tgataccacc ttttgccgct gcgcgagtac cggtttcata accttcccag
    18541 tggctacgac ccggttcaga aatatgggtg tgcgcatcaa ccatgcccgg cgaaaccacc
    18601 agaccagacg catccataac ttcttttgca tcgcccagat cctgaccgat agcagcaatt
    18661 tttccgcctt taacggcgat atctacaacg cgagcttcgt tttctaaaat aacggtgccg
    18721 tttttaatga ttaaatcaaa agacataaca aactccttgt aaaatacaga ttggttttta
    18781 actcaatgtt caatatcggg attaattaac ctatggtttt ttgctctcct gttttttctg
    18841 ctgttgtacg tttctttaat aaggcgtagg ccgcaaaggc gacgatgacg ccgacaaacc
    18901 atgaaacacg cgataacggt tccataaagt gaataaactt accgccaaga gataaaataa
    18961 cggccaccag agttactgaa aacgcagtga ggttaaaacc gttatcgtaa tatttataat
    19021 cgccaggtgc ggtatacagt tcatcaagat taatttgtcc gcgcatcacc acaaaataat
    19081 gcgccatcat gacaccaatt accggaccaa gcattccgcc gataatatcg aggaaaagat
    19141 aaatgctgtc ctgattttcc attaatttcc acgggcagat cagcaagctg ataatactgg
    19201 caatcagtac gccgttttta taggtcagtt ttgtcggtgc aatggcggca atctgataac
    19261 cggctggaat aatattaccg gtcgcgttag tggagatagt tgtcatcaga ataaccagta
    19321 ccgcaaagaa cgaggcgaac aggctgtccc aacgctgaac aatatccagc acgttccagg
    19381 tatcagcgcc gtagtgaata ctggctccgg caataataca taccccggcg accgcaaaca
    19441 gaatataggc cacaactaaa cccagcgttt gccccagcgc ctgctcacga aacgagtggg
    19501 cgttttgcgt aaagtcggat gcgctcaccg ccggtgccgc ccagaccgca actaccgcgt
    19561 taatcaccac caggaacagg aagccaccgt tttctgcttt ctgaataccg ctcggaatgt
    19621 agtcaaagat tggaccgatc ccgaccagtg aaatcgccca aatcgccata ccgccgaaaa
    19681 cgatatagat gcacgggtta agaatggcag tgaatttatt taaaactttg ccaccgccaa
    19741 aacctatacc aacgttgacc agccagaaga ttaagaaagt aattaagccc ggtagagaaa
    19801 ggcctaacag agtgaaatca ccaccgagag ttaaaaatcc cggccagatt ttgccaatca
    19861 gaatcaagca ggccagtgac cccgcgtaac attgcaaacc aaaccacatg atggcggcaa
    19921 ttccgcccct taataatccg ggaaacagtg caccacgtac accgtaagaa gcacgcagga
    19981 tcatggcaaa aggcacaccg tatttactgc ccgcagcacc gtttaatacc attaccgcgg
    20041 caatgaaaaa ggcgctgagg ataattgcca gcataatact aaaggtagac aagccgagaa
    20101 taaaaaagcc gccgaccatc acataattgg gaacgttatg aaccgaaccc atccataagg
    20161 taaaatagtt aaatgttttc caggtccgct ggctttgcgt tttcggcaat agatcttcgc
    20221 tatagccgcg ttgctggaat agttttctct gatgttccat aaatccctct taatttcacg
    20281 tatcgaataa cgttgtttta atctagctat gaggaacaaa taaaataaaa atattatttt
    20341 taatactgaa gcaacatctt tggctgcttt cttttttaat attgctggcc gattcatttt
    20401 ctgatatcgg ccatttttat tgcgggtatc aggccagttt atggttagcc attaattcca
    20461 gcgcctgcac taacgcagag tgatccaact ggctgccacc gtttgccgca caggtattaa
    20521 ataactcctg gcaggtcgca gtgtttggca ggttcagcgc aagtgctttc gcactttgca
    20581 gtgccaggtt gagatctttc tggtgcagag cgattttgaa gcccggatta aaggtgcgtt
    20641 taatcatacg ctcgccatga acttccagaa tacgtgagga agcaaagccg cccatcagcg
    20701 cctggcgcac acgtaccggg tccgcaccgg cttttgaagc aaatagcagg gcttcagaaa
    20761 ccgcttcaat attgagcgcc acgataatct gatttgccac tttgcaggtt tgaccatcgc
    20821 cgttaccgcc cacgagggtg atatttttac cgagcagttc aaacagcggt ttaacacgtt
    20881 caaataccgc ttcatcaccg ccaaccataa tcgacaacgt cccttcacgc gcaccgattt
    20941 caccgccgga gactggcgca tcgagataat cgccgcccag ttcattcacc tgacgagcga
    21001 aacgcttagt ttcaatcggg gaaatggagc tcatatcaac aatggttttg cccttcagcg
    21061 aggctttggt acaaccattt tcaccgaaca gaacttcttc aacctgaggt gtgtccggca
    21121 ccataataaa aatgatgtcc gatgcttccg ttacctggcg agcagtttca acactgacgg
    21181 cacccagtga cagtaattca tcagcaaccg gtccaatggt cgtgacatgt aattgatgac
    21241 cggcacgcgc cagattaatg gccatcggtg tacccataat gcctaagcca ataaatccca
    21301 gtttcataat taacctcttt taaatttcgc ttttcctgaa ttcagacaac acgatcccct
    21361 gccaacttag cggcctaaaa aagcattgtc tgaatagcgt tacgttttaa cggtacggat
    21421 ccatccagcg taaaccggct tccgtggtgg tttggggttt atattcacac ccaacccaac
    21481 cgttgtagtc agaattttcg attaccttaa agagataatc ataattaatt tctccggttc
    21541 ccggttcgcc gcgatgcgga ttatcggcaa tttgcaggtg accaatttta tcagcccact
    21601 gagtcatggt gttggttaat tcaccttcca tccgctgcat atgataaatg tcatactgaa
    21661 ttttcaaatt gcagcaacca acatcatcaa tcaatttcag cgcctgccga gttccggtga
    21721 gatggaaacc aggaatatca aaatggttaa taggttcaat cagtaataaa atatcttctt
    21781 tcatcagcat attcgcggca taacgcaggt tttctacaag cgttgcgtga atctgttcac
    21841 tgctgaaacc agccggcgtt ttaccgacca gacagttaat ttttttatta cccagcgcac
    21901 gggcataacg aatcgctgct gctacgccat cccgaaactc ttcttcacgg ccaggaatac
    21961 aggcaatacc gcgctccccc gccgcccagt cacccgccgg taaattgtgc agcgtatgtt
    22021 cgagtttatt actcgccagc acatgtttta attcttcaat gtcgtagtca taaggaaaca
    22081 taaattcaac gccgcgaaaa ccacactgcg cagctttctc aaaacgggcg agaaaatcat
    22141 attctccaaa taacatcgat aaattagcag agaaacgtaa cattatttat ctcccttatt
    22201 catagtgcat gaagcaggtt tcagtcggtg cgtccgctgc gttatcggcg atatcttcaa
    22261 attccatgac gttatccagt tcgctgccca tcgaaatatt ggtcacacgc tcgagaataa
    22321 cttccacgac taccggtacc cgatattgcg ccattaaggc tttcgcctgt tcaaaggctg
    22381 gcgcaatatc ttccggtttg aagacccgaa tagctttaca acctaaacct tccgctactt
    22441 ttacgtggtc aacaccgtag ccattcactt cactggagtt gatattctcg aaagcgagtt
    22501 gcacgcagta gtccatgtca aaagcgcgtt gtgactgacg aatcagcccc agataagcgt
    22561 tgttgaccag cacatggatg tacggaatgt tgaactgcgc gccaacagct aactcttcaa
    22621 tcaggaactg gaagtcaaag tcgccagaaa tcgccaccac attgcgtttc ggatcagcgg
    22681 cacaaacccc tagcgcagcc ggaatcgtcc agcctaacgg accagcctga ccacagttga
    22741 tccagtggcg gtctttaaag acatgcagca tttgtgccgc agcgatttgt gacagaccaa
    22801 tggtggtgac ataacaaaca tcgcgaccaa aggctttgtt catctcttca tacacgcgct
    22861 gcggtttcac cggcacgttg tcgaagtggg ttttgcgcag caaagtgcgt ttacgctgct
    22921 ggcagtcggc gacccattct ttacgacacg gcagacgacc cgctttttgc atctcctgcg
    22981 ccacttcaac cagtagtgtc agcgccgctt tagcatcaga gacaataccg agatccggac
    23041 acagcacgcg accaatttgc gtcggctcaa tatcaatatg aacgattttg cgcccttcgg
    23101 tgtatttctc taccgagccg gtatgacggt tagcaaaacg gttaccgata ccaaacacca
    23161 tgtcagacgc cagcagcgtt gcgttaccgt aacgatgcgc ggtttgcaga cccaccatcc
    23221 cggccatcag ttcatgatcg tccgggatac agccccagcc cattagcgtt gggatcaccg
    23281 gaacgctggt cagttcagca aactgttgta acagtgcagc tgcgtcagca ttaattaccc
    23341 cgcccccggc aacaatcacc ggacgttcgg cctggattaa catttctaca gctttttcga
    23401 tctgcatacg gctggcagca ggtttgtaga ccggcagcgg ttcgtacatg tcaggatcaa
    23461 actcgatttc cgcaacctga acgtcgaacg gtaaatccac cagtaccgga cccggacgac
    23521 cagaacgcat caggtgaaat gcctgttgca gcacgcgagg caccagcgcc gcttcacgaa
    23581 ctgtaaccgc cattttgctg accggtttag caattgcttc aatatctacg gcctgaaaat
    23641 cttctttatg cagacgggcg cgcggtgcct ggccggtaat gcacagaata ggaatggaat
    23701 cagcagaagc ggaatagagc gcggtgatca tgtccgtgcc cgcaggaccg gaagtcccca
    23761 gacatacgcc gatattccct gccgttgcgc gggtataacc ttccgccatg tgcgaagcac
    23821 cttccacatg acgcgccaga atgtgacgaa taccgccgtg cttacgcatc gctgagtaga
    23881 acggattgat tgcagctccc ggaacaccga aggcggtagt gataccttct ttctccagca
    23941 catacattgc cgcgtcaacg gctctcattt ttgccatttt attcctacct ctatttattg
    24001 gaaaattttt ccaactttca aattttgtca aaaaaacccg ctccgcagag cgggatgcga
    24061 cagacattat ggatgtgctt tcagtcccaa cgccgtgctg atatcgcggg cggtgtctct
    24121 gaccagctca ccctgactga caaaacgatc ttctgtcagt cttgatgaag gcccggagat
    24181 ggagatagcg gcaacaacac taccgacatc atcgtaaatt gctgaagcta tgcaattcag
    24241 acctacaaca tgctcttctt tatctacggt atagcccagt tcacgcgctt gttccaggtc
    24301 cttcagcaag gtgggcatat ccacaagcgt agttggcgta aactgctgca aaccggtttg
    24361 cagaatgatg ctcatcaact cctcttccgc cagcggataa agcagcgctt tgcccgcacc
    24421 ggaagcatgc agtggcagac gactgcccag tggcgcacac atcctgacca tcgatttaca
    24481 ctctaactga ccaattaata ccgcttcatt gccgttacgg atcgcgacat tgaccgtttc
    24541 gccggaaagt aacatcaggc ggcgcataaa cggcccggcg acggagagga catcgcggtt
    24601 atggatgtac gccgcaccga cgttaaagac acctaatcct atatgccacc agcctaattg
    24661 actgtcctga tagacaaaat ccgctgcctg taaaaccttc agcaagcgaa aggtcgtgga
    24721 gagcggcaaa tccagattga gagaaatatc gctaaccgac gaacttcccc cacttttttc
    24781 caaatattgc agaatcgcaa ttccccgctc taacgcctgt gcgcccttct gtgccacagg
    24841 ctccgcctgt cctggcctgc cgcgccgtct aacttccgtc atacctacgt taactccgac
    24901 ctacaagtga gcataaacaa tgaacaatta gtttatctta tgcaagtcgg ttgcaggcgt
    24961 cacgcaaaac agagttcctg ttcaggaata ctttcaacat cacagttgtc actgccgccg
    25021 cgatcgatgg tcagaaaatc ggtgacgcgc tgccaggcga aaagtgggtg atgccagacg
    25081 ttacgatggt aattcactcc ctgttcgccg ttggtgataa acgcccgcag cgttgacagg
    25141 tctggtttgt cgtcacctaa cgccacgacc accacaaaca cctcaccttt catcgggata
    25201 aaggcctgag tacccagcgg atgacgttcg agttcgtgaa tggtcagcgg cagattcgcc
    25261 ggttgcgcgc ggttaatgct gataagcgta cggtcttgct caagaatctc aaccagcgcc
    25321 aaatcgtggt aacgctccac caggccattg ttaatatgga aaaaatcccg ttgctgcgtt
    25381 tcgattacgt cgccataagc actaaaggct tcctgactta acggtaatac ctgaagtttc
    25441 atctttttgt ccttgtaaca taattccgtt caaccaccgc cgaccggtca gcttggtttc
    25501 aataacaggc aatctaaaac cttaagagaa caacatcaat acaaaagttg gaatattttt
    25561 ccaaaactag atttagtcca caaattgaac agggttatca tgtaaaaata ctgataaatc
    25621 agaggataag aaaatcacgc aacttgcgga tttaaaaggg gatacctgaa gatgttcgat
    25681 ccagaaacct tgcggacttt cattgcggtt gctgaaacag gaagtttttc aaaagcggca
    25741 gaacgattat gtaaaaccac ggcgacgatc agttatcgca ttaaacttct ggaagagaat
    25801 accggagtag cgctgttttt ccgtacgact cgcagcgtga cgttgacagc ggctggcgag
    25861 catctacttt cccaggccag agactggctg agctggctgg aaagtatgcc aagcgagctg
    25921 caacaggtga atgatggcgt ggaacgccag gtgaatattg tcatcaacaa cctgctctac
    25981 aacccccagg ccgtcgccca gttgctggcg tggctgaatg agcgttaccc ctttacccag
    26041 tttcacatct cccgacaaat ctatatgggc gtctgggact cgctattgta cgaaggtttt
    26101 tcgctggcta tcggcgtcac gggaactgag gcgctggcaa atacctttag tcttgatccc
    26161 ttaggatcgg tgcaatggcg ctttgtcatg gcggcggatc atccgctggc gaacgttgaa
    26221 gagccgctaa cagaagcgca gttgcggcgc tttccggcgg tcaatattga agacagcgcc
    26281 cgcaccttaa ccaaacgcgt cgcctggcga ttgccagggc aaaaagagat tattgttccc
    26341 gatatggaaa cgaaaatcgc cgcccatctg gcgggcgttg gcattggttt tttgccaaaa
    26401 tcgctttgcc agtcaatgat cgataatcaa caactggtca gccgggtaat cccaacgatg
    26461 cgccctcctt cgccattgag tctggcatgg cgcaaatttg gcagcggcaa agcggtagaa
    26521 gatattgtga ccttgtttac ccagcgcagg ccggaaatca gcggattttt agaaattttc
    26581 ggcaacccac gcagttaaaa atcaagtttc cttgcgcgtt ggcgcgtaaa atagcgcgca
    26641 agctgatttg aggttcactt ttaactatgc aagagagaca cacggaacag gactatcgtg
    26701 ccctgctgat tgctgatacg cccattattg atgttcgcgc ccctatcgag tttgagcacg
    26761 gcgcaatgcc cgccgctatc aatctgccgt taatgaataa cgatgaacgc gccgccgttg
    26821 gcacctgcta taaacagcaa ggctcagacg cagcgctggc gctgggacat aaactggtgg
    26881 cgggtgaaat tcgtcagcag cgcatggacg cctggcgggc agcgtgcctg caaaatccgc
    26941 aaggtattct ctgctgcgcc cgtggcggtc agcgctcaca tattgtgcaa agctggttgc
    27001 atgcagcggg gattgattat ccgctggtgg aaggcggtta taaggcactg cgccagaccg
    27061 cgattcaggc gactattgaa ctggcacaaa aaccgatagt gctgattggc ggttgtaccg
    27121 gcagcggtaa aacgctgtta gtgcagcaac agccgaacgg tgttgatctg gaagggttgg
    27181 cgcgtcatcg cggttcggcg tttggtcgca cgttacaacc acaacttagc caggcgagtt
    27241 ttgaaaacct gctggctgcc gaaatgctaa aaaccgacgc ccgtcagaat ttgcgcctgt
    27301 gggtgctgga agacgaaagc cggatgatcg gttcgaatca cctgccggaa tgcctgcgcg
    27361 agcgaatgac tcaggcggcg attgcggtgg tagaagatcc gtttgagatc cgtcttgagc
    27421 gcctgaacga agagtatttc ttgcgtatgc atcatgattt tacccacgcg tacggcgacg
    27481 aacagggctg gcaggagtat tgcgaatacc tgcatcacgg actttcggcg attaagcgtc
    27541 ggctggggct acagcgctat aacgaactgg ctgcaaggct ggatgcagca ctgacaacgc
    27601 aactcaccac cggcagcacc gacggtcatc tggcctggct ggtgccgtta cttgaagaat
    27661 attacgaccc gatgtatcgc tatcagcttg agaaaaaagc ggaaaaagtt gtctttcgcg
    27721 gtgagtgggc ggaagtggcg gaatgggtta aggcgcggta atgagggacg tatttgtatt
    27781 agtcgcgact tgatctgaca catggccttg aaaggttgag agttaccggt tttgatatga
    27841 gtgtcgaatc cttatccaaa acaagaggta actctcatgc ttcatactgc caatcccgtc
    27901 atcaaacaca aagccggttt gctcaatctg gctgaagaac tcagcaacgt atcaaaagcc
    27961 tgtaaaatca tgggcgtttc gcgtgatacg ttttatcgtt accgcgaact ggtcgctgaa
    28021 ggcggtgtgg atgcgcagat taatcgtagt tgccgcgctc ctaaccttaa gaaccgtacc
    28081 gatgaggcaa ctgaacaggc tgttgttgat tacgccgtcg ctttcccgac acatggtcag
    28141 caccgggcca gcaacgagct gcgtaaacag ggggttttta tctccgacag tggtgtccgt
    28201 tctgtctggt tactccataa ccttgagaat ctcaaaagac gatactgaac aaattttatc
    28261 aggtgacgtt ccgtaaaaag ttgtatggag ttctcgatgc agtcggcgcg actatcagta
    28321 cccccgctga accctggact atcgggccgc cgtactgggg catgtcaccc tggcgtgccg
    28381 ctggttttcc gctaatggtt tatttcctct ttctttcccg gcaagaattt attttaatcc
    28441 ggaaggatta tttattttca gatagggact cacattaaac acgtaacatt ttaattaatg
    28501 catggctgaa tatgtattac acaatgtcag atatcgtaaa agaccagtgc aattctatgt
    28561 aaactctctg actgttcatt ttatttgttg tttcagggtc ggaactcacc ctcaataaac
    28621 aactgaatac gagtagatat tcatcgtctg agctatatgg ctttacacaa tagccgacat
    28681 gtcttttctc agtcaggaat tttacttttc ctcactacga agttgacgac ttcgatatgg
    28741 gatagactct taattcaagc aattactctg cacaagcatc aggcaatcca gctccaatat
    28801 ttgttataaa ataatgcgta acattaattt caccaacaaa aaaaaggttt acaccatccc
    28861 cttgccctgg tatcttacca tatttacacc acactttttt tgtatctgga tcattctttg
    28921 atacgatttt cgccacttgt tccctggccc tcactgtcaa tgttttctta aacctacccc
    28981 catcatcatt tgttagggaa aaataagaaa aaaataatca tcttctaca
//
LOCUS       DAPOAV010000055        28091 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.055, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000055 DAPOAV010000000
VERSION     DAPOAV010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 28091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28091
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.055"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            249..2672
                     /gene="pgaA"
                     /locus_tag="RN951_002732"
     CDS             249..2672
                     /gene="pgaA"
                     /locus_tag="RN951_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6 N-acetyl-D-glucosamine export
                     porin PgaA"
                     /protein_id="HDX2527708.1"
                     /translation="MYSSSRKRCPKTKWALKLLTAAFLAASPAAKSAVNNAYDALIIE
                     ARKGNTQPALSWFALKSALSNNQIADWLQIALWAGQDKQVITVYNRYRHQQLPARGYA
                     AVAVAYRNLQQWQNSLTLWQKALSLEPQNKDYQRGQILTLADAGHYDTALVKLKQLNS
                     GAPDKANLLAEAYIYKLAGRHQDELRAMTESLPENASTQQYPTEYVQTLRNNQLAAAI
                     DDANLTPDIRADIHAELVRLSFMPTRSESERYAIADRALAQYAALEILWHDNPDRTAQ
                     YQRIQVDHLGALLTRDRYKDVISHYQRLKKTGQIIPPWGQYWVASAYLKDHQPKKAQS
                     IMTELFYHKETIAPDLSDEELADLFYSHLESENYPGALTVTQHTINTSPPFLRLMGTP
                     TSIPNDTWLQGHSFLSTVAKYSNDLPQAEMTARELAYNAPGNQGLRIDYASVLQARGW
                     PRAAENELKKAEVIEPRNINLEVEQAWTALTLQEWQQAAVLTHDVVEREPQDPGVVRL
                     KRAVDVHNLAELRIAGSTGIDAEGPDSGKHDVDLTTIVYSPPLKDNWRGFAGFGYADG
                     QFSEGKGIVRDWLAGVEWRSRNIWLEAEYAERVFNHEHKPGARLSGWYDFNDNWRIGS
                     QLERLSHRVPLRAMKNGVTGNSAQAYVRWYQNERRKYGVSWAFTDFSDSNQRHEVSLE
                     GQERIWSSPYLIVDFLPSLYYEQNTEHDTPYYNPIKTFDIVPAFEASHLLWRSYENSW
                     EQIFSAGVGASWQKHYGTDVVTQLGYGQRISWNDVIDAGATLRWEKRPYDGDREHNLY
                     VEFDMTFRF"
     gene            2681..4699
                     /gene="pgaB"
                     /locus_tag="RN951_002733"
     CDS             2681..4699
                     /gene="pgaB"
                     /locus_tag="RN951_002733"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6-N-acetyl-D-glucosamine
                     N-deacetylase PgaB"
                     /protein_id="HDX2527709.1"
                     /translation="MLRNGNKYLLMLVSIIMLTACISQSRTSFIPPQDRESLLAEQPW
                     PHNGFVAISWHNVEDEAADQRFMSVRTSALREQFAWLRENGYQPVSIAQIREAHRGGK
                     PLPEKAVVLTFDDGYQSFYTRVFPILQAFQWPAVWAPVGSWVDTPADKQVKFGDELVD
                     REYFATWQQVREVARSRLVELASHTWNSHYGIQANATGSLLPVYVNRAYFTDHARYET
                     AAEYRERIRLDAVKMTEYLRTKVEVNPHVFVWPYGEANGIAIEELKKLGYDMFFTLES
                     GLANASQLDSIPRVLIANNPSLKEFAQQIITVQEKSPQRIMHIDLDYVYDENLQQMDR
                     NIDVLIQRVKDMQISTVYLQAFADPDGDGLVKEVWFPNRLLPMKADIFSRVAWQLRTR
                     SGVNIYAWMPVLSWDLDPTLTRVKYLPTGEKKAQIHPEQYHRLSPFDDRVRAQVGMLY
                     EDLAGHAAFDGILFHDDALLSDYEDASAPAITAYQQAGFSGSLSEIRQNPEQFKQWAR
                     FKSRALTDFTLELSARVKAIRGPHIKTARNIFALPVIQPESEAWFAQNYADFLKSYDW
                     TAIMAMPYLEGVAEKSADQWLIQLTNQIKNIPQAKDKSILELQAQNWQKNGQHQAISS
                     QQLAHWMSLLQLNGVKNYGYYPDNFLHNQPEIDLIRPEFSTAWYPKND"
     gene            4692..6017
                     /gene="pgaC"
                     /locus_tag="RN951_002734"
     CDS             4692..6017
                     /gene="pgaC"
                     /locus_tag="RN951_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6 N-acetyl-D-glucosamine synthase"
                     /protein_id="HDX2527710.1"
                     /translation="MINRIVSFFILCLVLCIPLCVAYFHSGELMMRFVFFWPFFMSIM
                     WIVGGVYFWVYRERHWPWGENAPAPQLKDNPSISIIIPCFNEEKNVEETIHAALAQRY
                     ENIEVIAVNDGSTDKTRAILDRMAAQIPHLRVIHLAQNQGKAIALKTGAAAAKSEYLV
                     CIDGDALLDRDAAAYIVEPMLYNPRVGAVTGNPRIRTRSTLVGKIQVGEYSSIIGLIK
                     RTQRIYGNVFTVSGVIAAFRRSALAEVGYWSDDMITEDIDISWKLQLNQWTIFYEPRA
                     LCWILMPETLKGLWKQRLRWAQGGAEVFLKNMTRLWRKENFRMWPLFFEYCLTTIWAF
                     TCLVGFIIYAVQLAGVPLNIELTHIAATHTAGILLCTLCLLQFIVSLMLENRYEHNLT
                     SSLFWIIWFPVIFWMLSLATTLVSFTRVMLMPKKQRARWVSPDRGILRG"
     gene            6019..6432
                     /gene="pgaD"
                     /locus_tag="RN951_002735"
     CDS             6019..6432
                     /gene="pgaD"
                     /locus_tag="RN951_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6-N-acetyl-D-glucosamine
                     biosynthesis protein PgaD"
                     /protein_id="HDX2527711.1"
                     /translation="MNNLIITTRQSPVRLLVDYVATTILWTLFALFIFLFAMDLLTGY
                     YWQSEARSRLQFYFLLAVANAVVLIVWALYNKLRFQKQQHHAAYQYTPQEYAESLAIP
                     DELYQQLQKSHRMSVHFTSQGQIKMVVSEKALVRA"
     gene            complement(6482..7270)
                     /gene="phoH"
                     /locus_tag="RN951_002736"
     CDS             complement(6482..7270)
                     /gene="phoH"
                     /locus_tag="RN951_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PhoH"
                     /protein_id="HDX2527712.1"
                     /translation="MGRQKAVIKARREAKRVLRRDSRSHKQREEESVTSLVQMGGVEA
                     IGMARDSRDTSPILARNEAQLHYLKAIESKQLIFATGEAGCGKTWISAAKAAEALIHK
                     DVDRIIVTRPVLQADEDLGFLPGDIAEKFAPYFRPVYDVLVRRLGASFMQYCLRPEIG
                     KVEIAPFAYMRGRTFENAVVILDEAQNVTAAQMKMFLTRLGENVTVIVNGDITQCDLP
                     RGVCSGLSDALERFEEDEMVGIVRFGKEDCVRSALCQRTLHAYS"
     gene            complement(7891..9162)
                     /gene="efeB"
                     /locus_tag="RN951_002737"
     CDS             complement(7891..9162)
                     /gene="efeB"
                     /locus_tag="RN951_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deferrochelatase/peroxidase EfeB"
                     /protein_id="HDX2527713.1"
                     /translation="MQYKDENGVNEPSRRRLLKVIGALALAGSCPVAHAQKTQSAPGT
                     LSPDARNEKQPFYGEHQAGILTPQQAAMMLVAFDVLASDKADLERLFRLLTQRFAFLT
                     QGGAAPETPNPRLPPLDSGILGGYIAPDNLTITLSVGHSLFDERFGLAPQMPKKLQKM
                     TRFPNDSLDAALCHGDVLLQICANTQDTVIHALRDIIKHTPDLLSVRWKREGFISDHA
                     ARSKGKETPINLLGFKDGTANPDSQNDKLMQKVVWVTADQQEPAWTIGGSYQAVRLIQ
                     FRVEFWDRTPLKEQQTIFGRDKQTGAPLGMQHEHDVPDYASDPEGKVIALDSHIRLAN
                     PRTAESESSLMLRRGYSYSLGVTNSGQLDMGLLFVCYQHDLEKGFLTVQKRLNGEALE
                     EYVKPIGGGYFFALPGVKDANDYFGSALLRV"
     gene            complement(9168..10295)
                     /gene="efeO"
                     /locus_tag="RN951_002738"
     CDS             complement(9168..10295)
                     /gene="efeO"
                     /locus_tag="RN951_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron uptake system protein EfeO"
                     /protein_id="HDX2527714.1"
                     /translation="MTINFRRNALQLSVAALFSSAFMANAADVPQVKVTVTDKQCEPM
                     TITVNAGKTQFIIQNHSQKALEWEILKGVMVVEERENIAPGFSQKMTANLQPGEYDMT
                     CGLLTNPKGKLIVKGEATADAAQSDALLSLGGAITAYKAYVMAETTQLVTDTKAFTDA
                     IKAGDIEKAKALYAPTRQHYERIEPIAELFSDLDGSIDAREDDYEQKAADPKFTGFHR
                     LEKALFGDNTTKGMDQYAEQLYTDVVDLQKRISELAFPPSKVVGGAAGLIEEVAASKI
                     SGEEDRYSHTDLWDFQANVEGSQKIVDLLRPQLQKANPELLAKVDANFKKVDTILAKY
                     RTKDGFETYDKLTDADRNALKGPITALAEDLAQLRGVLGLD"
     gene            complement(10353..11183)
                     /locus_tag="RN951_002739"
     CDS             complement(10353..11183)
                     /locus_tag="RN951_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FTR1 family protein"
                     /protein_id="HDX2527715.1"
                     /translation="MFVPFLIMLREGLEAALIVSLIASYLKRTQRGRWIGVMWIGVLL
                     AAALCLGLGIFINETTGEFPQKEQELFEGIVAVIAVVILTWMVFWMRKVSRNVKVQLE
                     QAVDSALQRGNHHGWALVMMVFFAVAREGLESVFFLLAAFQQDVGIWPPLGAMLGLAT
                     AVVLGFLLYWGGIRLNLGAFFKWTSLFILFVAAGLAAGAIRAFHEAGLWNHFQEIAFD
                     MSAVLSTHSLFGTLMEGIFGYQEAPSVSEVAVWFIYLIPALVAFALPPRAGATASRSA
                     "
     gene            complement(11726..13234)
                     /gene="putP"
                     /locus_tag="RN951_002740"
     CDS             complement(11726..13234)
                     /gene="putP"
                     /locus_tag="RN951_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/proline symporter PutP"
                     /protein_id="HDX2527716.1"
                     /translation="MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGP
                     FVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTE
                     YNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSY
                     ETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGFGDSLEV
                     IKQKSIENVDMLKGLNFVAIISLMGWGLGYFGQPHILARFMAADSHHSIVHARRISMT
                     WMILCLAGAVAVGFFGIAYFNDHPALAGAVNQNAERVFIELAQILFNPWIAGILLSAI
                     LAAVMSTLSCQLLVCSSAITEDLYKAFLRKHASQKELVWVGRVMVLVVALVAIALAAN
                     PENRVLGLVSYAWAGFGAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFGWL
                     GLYEIIPGFIFGSIGIVVFSLLGKAPSAAMQKRFAEADAHYHSAPPSRLQES"
     gene            complement(13393..13602)
                     /locus_tag="RN951_002741"
     CDS             complement(13393..13602)
                     /locus_tag="RN951_002741"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527717.1"
                     /translation="MMLQLCATMLNVTCVASLKMNEMLIKEIDMTGIKKITQTFSLRQ
                     LTFLKGATAKNVRECNLMKNSVAEH"
     gene            13657..17619
                     /gene="putA"
                     /locus_tag="RN951_002742"
     CDS             13657..17619
                     /gene="putA"
                     /locus_tag="RN951_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trifunctional transcriptional regulator/proline
                     dehydrogenase/L-glutamate gamma-semialdehyde
                     dehydrogenase"
                     /protein_id="HDX2527718.1"
                     /translation="MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQL
                     ENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRP
                     ETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQ
                     EGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGK
                     LVSTHNEASLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLE
                     EKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALH
                     PRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEESDRLEISLDLLEKLCFEPE
                     LAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGL
                     EGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQY
                     EFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSF
                     VNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDL
                     ANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGYVREATPR
                     EVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAI
                     AEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNS
                     VLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGRGETVGAQLTGDDRVRGVIFTGS
                     TEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVLASAFDSAG
                     QRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHI
                     QTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYN
                     RNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPF
                     GGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAKYPVDAQLKAALTQPLNAL
                     REWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQDAL
                     TQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDS
                     DQLRALCEAVAARDGTIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
                     "
     gene            complement(17659..18297)
                     /gene="rutR"
                     /locus_tag="RN951_002743"
     CDS             complement(17659..18297)
                     /gene="rutR"
                     /locus_tag="RN951_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator RutR"
                     /protein_id="HDX2527719.1"
                     /translation="MTQGAVKTTGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQI
                     AELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKL
                     EVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQ
                     HLIFMIWASTQHYADFAPQVEAVTGATLRDEVFFNQTVENVQRIIIEGIRPR"
     gene            18585..19676
                     /gene="rutA"
                     /locus_tag="RN951_002744"
     CDS             18585..19676
                     /gene="rutA"
                     /locus_tag="RN951_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309285.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein A"
                     /protein_id="HDX2527720.1"
                     /translation="MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDF
                     ALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAA
                     TIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKS
                     DFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSARYADFNFCFGKGVNTPTAFA
                     PTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQ
                     KDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDF
                     LSGIETFGERIQPLMQCRAHLPALTQEVA"
     gene            19676..20368
                     /gene="rutB"
                     /locus_tag="RN951_002745"
     CDS             19676..20368
                     /gene="rutB"
                     /locus_tag="RN951_002745"
                     /EC_number="3.5.1.110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415531.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxyureidoacrylate/ureidoacrylate
                     amidohydrolase RutB"
                     /protein_id="HDX2527721.1"
                     /translation="MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVS
                     TTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQP
                     QLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTG
                     IATNVCVESTLRDGFFLEYFGVVLEDATHQAGPKFAQKAALFNIETFFGWVSDVETFC
                     DALSPTSFAHIA"
     gene            20380..20766
                     /gene="rutC"
                     /locus_tag="RN951_002746"
     CDS             20380..20766
                     /gene="rutC"
                     /locus_tag="RN951_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein C"
                     /protein_id="HDX2527722.1"
                     /translation="MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLF
                     ADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKP
                     ARFCIQCGLVKPDALVEIATIAHIAK"
     gene            20774..21574
                     /gene="rutD"
                     /locus_tag="RN951_002747"
     CDS             20774..21574
                     /gene="rutD"
                     /locus_tag="RN951_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein D"
                     /protein_id="HDX2527723.1"
                     /translation="MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVC
                     YDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYP
                     ASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPR
                     LEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSS
                     ELHAALPDSQKMVMPYGGHACNVTDPETFNALLLNGLASLLHHREAAL"
     gene            21584..22174
                     /locus_tag="RN951_002748"
     CDS             21584..22174
                     /locus_tag="RN951_002748"
                     /EC_number="1.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonic semialdehyde reductase"
                     /protein_id="HDX2527724.1"
                     /translation="MNEAVSPGALSTLFTDARTHNGWRETPVSDETLREIYALMKWGP
                     TSANCSPARIVFTRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPLLFP
                     HGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQHVDDAFFT
                     GSTLKSNLLINIGYGDSSKLYARLPRLSFEEACGLL"
     gene            22185..22679
                     /gene="rutF"
                     /locus_tag="RN951_002749"
     CDS             22185..22679
                     /gene="rutF"
                     /locus_tag="RN951_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415527.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization flavin reductase protein
                     F"
                     /protein_id="HDX2527725.1"
                     /translation="MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTD
                     TPPTLLVCLNRGASVWPAFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQT
                     GVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHTTPYGLVWFDRSYHALM
                     RPAC"
     gene            22700..24028
                     /gene="rutG"
                     /locus_tag="RN951_002750"
     CDS             22700..24028
                     /gene="rutG"
                     /locus_tag="RN951_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization transport protein G"
                     /protein_id="HDX2527726.1"
                     /translation="MAMFGFPHWQLKSTSTESGVVAPDERLPFAQTAVMGVQHAVAMF
                     GATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNG
                     QGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAP
                     IAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLG
                     LGKAVDFTLVSHAAWFGLPHFSTPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGR
                     NMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAML
                     LGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTL
                     VLGAGDFALTLGGFTLGGIGTATFGAILLNALLSRKLVDVPPPEVVHQEP"
     gene            complement(24285..24458)
                     /locus_tag="RN951_002751"
     CDS             complement(24285..24458)
                     /locus_tag="RN951_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415525.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HDX2527727.1"
                     /translation="MANHRGGSGNFAEDRERASEAGKKGGQHSGGNFKNDPQRASEAG
                     KKGGKSSHGKSDN"
     gene            24831..25427
                     /gene="wrbA"
                     /locus_tag="RN951_002752"
     CDS             24831..25427
                     /gene="wrbA"
                     /locus_tag="RN951_002752"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H:quinone oxidoreductase"
                     /protein_id="HDX2527728.1"
                     /translation="MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMP
                     PQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGA
                     LYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPY
                     GATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG"
     gene            25448..25675
                     /locus_tag="RN951_002753"
     CDS             25448..25675
                     /locus_tag="RN951_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002898701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccJ family protein"
                     /protein_id="HDX2527729.1"
                     /translation="MPTQEAKAHHVGEWASLRNTSPEIAEAIFEVAGYDEKMAEKIWE
                     EGSDEVLVKAFAKTDKDSLFWGEQTIERKNV"
     gene            complement(25713..26954)
                     /gene="agp"
                     /locus_tag="RN951_002754"
     CDS             complement(25713..26954)
                     /gene="agp"
                     /locus_tag="RN951_002754"
                     /EC_number="3.1.3.10"
                     /EC_number="3.1.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glucose-1-phosphatase/inositol
                     phosphatase"
                     /protein_id="HDX2527730.1"
                     /translation="MNKTLIAAAVAGIVLLASNAQAQTVPEGYQLQQVLMMSRHNLRA
                     PLANNGSVLEQSTPNKWPEWDVPGGQLTTKGGVLEVYMGHYMREWLAEQGMVKSGECP
                     PPYTVYAYANSLQRTVATAQFFITGAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAF
                     SEQAVAAMEKELSKLQLTDSYQLLEKIVNYKDSPACKEKQQCSLVDGKNTFSAKYQQE
                     PGVSGPLKVGNSLVDAFTLQYYEGFPMDQVAWGEIKSDQQWKVLSKLKNGYQDSLFTS
                     PEVARNVAKPLVSYIDKALVTDRTSAPKITVLVGHDSNIASLLTALDFKPYQLHDQNE
                     RTPIGGKIVFQRWHDSKANRDLMKIEYVYQSAEQLRNADALTLQAPAQRVTLELSGCP
                     IDADGFCPMDKFDSVLNEAVK"
     gene            complement(27247..>28091)
                     /locus_tag="RN951_002755"
     CDS             complement(27247..>28091)
                     /locus_tag="RN951_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527731.1"
                     /translation="NFMEYIENINACDDVFSEYCFDDENISVQPERINTPGISDLDSD
                     IDLSGISFIQRETNQALGLKYAPVDGDGYCLLRAILVLKQHDYSWALVSYKMQKEVYN
                     EFIKMVDKKTIEALVDTAFYNLREDVKTLFGVDLQSDNQIQGQSSLMSWSFLFFKKQF
                     IDSCLNNEKCILHLPEFIFNDNKNLLALDTDTSDRIKAVKNFLAVLSDSICSLFIVNS
                     NVASISLGNESFSTDEDLEYGYLMNTGNHYDVYLPPELFAQAYKLNNKEMNAQLDYLN
                     RYAI"
BASE COUNT         6919 a         7261 c         7050 g         6861 t
ORIGIN      
        1 atttattttg aaaaaggcat tgggatttat gccgtattcc tgaagatcct catcattgga
       61 atggattttc gggcgagaaa aggattttat atggacactc tgctcatcat ttcttcttct
      121 catcatcaac aattcacgtc tctcttccgc gtttaataac ggattatgag gtgcaaaaat
      181 atctttcttt tcagttacct gtaattagat acagagagag attttggcaa tacatggagt
      241 aatacaggat gtattcaagt agcagaaaaa ggtgcccgaa aaccaaatgg gctttgaaac
      301 ttcttactgc cgcattttta gcagcgagtc ccgcggcgaa gagtgctgtt aataacgcct
      361 atgatgcatt gattattgaa gctcgcaagg gtaatactca gccagctttg tcatggtttg
      421 cactaaaatc agcactcagc aataaccaaa ttgctgactg gttacagatt gccttatggg
      481 ccgggcaaga taaacaggtt attaccgttt acaaccgcta ccgtcatcag caattaccag
      541 cgcgtggtta tgcagctgtc gccgtcgctt atcgtaacct gcaacaatgg caaaactcgc
      601 ttacactgtg gcaaaaggcg ctctctctgg agccgcaaaa taaggattat caacggggac
      661 aaattttaac cctggcagat gctggtcact atgatactgc gctggttaaa cttaagcagc
      721 ttaactctgg agcaccggac aaagccaatt tactcgcaga agcctatatc tataaactgg
      781 cggggcgtca tcaggatgaa ttacgggcga tgacagagtc attacctgaa aatgcatcta
      841 cgcaacaata tcccacagaa tacgtgcaga cattacgtaa taatcaactt gctgccgcga
      901 ttgacgatgc caatttaacg ccagatattc gcgctgatat tcatgccgaa ctggtcagac
      961 tgtcgtttat gcctacgcgc agtgaaagtg aacgttatgc cattgccgat cgcgccctcg
     1021 cccaatacgc tgcattagaa attctgtggc acgataaccc agaccgcact gcccagtacc
     1081 agcgtattca ggttgatcat cttggcgcgt tattaactcg cgatcgttat aaagacgtta
     1141 tttctcacta tcagcgatta aaaaagacgg ggcaaattat tccgccctgg gggcaatatt
     1201 gggttgcatc ggcttatctc aaagatcatc agccgaaaaa agcacagtca ataatgaccg
     1261 agctctttta tcacaaggag accattgccc cggatttatc cgatgaagaa cttgcggatc
     1321 tcttttacag ccacctggag agtgaaaatt atccgggcgc gctaactgtc acccaacata
     1381 ccattaatac ttcgccgcct ttccttcggt taatgggcac gcctacgagc atcccgaatg
     1441 atacctggtt acaggggcat tcgtttctct caaccgtagc aaaatatagt aatgatcttc
     1501 ctcaggctga aatgacagcc agagagcttg cttataacgc accaggaaat cagggactgc
     1561 gcattgatta cgcgagtgtg ttacaagccc gcggttggcc tcgtgcagca gaaaatgaat
     1621 taaaaaaagc agaagtgatc gagccacgta atattaatct ggaggttgaa caagcctgga
     1681 cagcattaac gttacaagaa tggcagcagg cagctgtctt aacgcacgat gttgtcgaac
     1741 gtgaaccgca agatcccggc gttgtacgat taaaacgtgc ggttgatgta cataatcttg
     1801 cagagcttcg tatcgctggc tcaacaggaa ttgatgccga aggcccggat agtggtaaac
     1861 atgatgtcga cttaaccacc atcgtttatt caccaccgct gaaggataac tggcgcggtt
     1921 ttgctggatt cggttatgcc gatggacaat ttagcgaagg aaaagggatt gttcgcgact
     1981 ggcttgcggg tgttgagtgg cggtcacgta atatctggct cgaggcagag tacgctgaac
     2041 gcgttttcaa tcatgagcat aaacccggcg cgcgcctgtc tggctggtat gattttaatg
     2101 ataactggcg tattggttcg caactggaac gcctctctca ccgcgttcca ttacgggcaa
     2161 tgaaaaatgg tgttacaggc aacagtgctc aggcttatgt tcgctggtat caaaatgagc
     2221 ggcgtaagta cggtgtctcc tgggctttca ctgatttttc cgacagtaac cagcgtcatg
     2281 aagtctcact tgagggtcag gaacgcatct ggtcttcacc atatttgatt gtcgatttcc
     2341 tacccagtct gtattacgaa caaaatacag aacacgatac cccatactac aaccctataa
     2401 aaacgttcga tattgttccg gcatttgagg caagccattt gttatggcga agctatgaaa
     2461 atagctggga gcaaatattc agcgcaggtg ttggtgcctc ctggcaaaaa cattatggca
     2521 cggatgtcgt cacccaactc ggctacgggc aacgcattag ttggaatgac gtgattgatg
     2581 ctggcgcaac gctacgctgg gaaaaacgac cttatgacgg tgacagagaa cacaacttat
     2641 acgttgaatt cgatatgaca ttcagatttt aaggataaat atgttacgta atggaaataa
     2701 atatctcctg atgctggtga gtataattat gctcaccgcg tgcattagcc agtcaagaac
     2761 atcatttata ccgccacagg atcgcgaatc tttactcgcc gagcaaccgt ggccgcataa
     2821 tggttttgta gcgatttcat ggcataacgt tgaagacgaa gctgccgacc agcgttttat
     2881 gtcagtgcgg acatcagcac tgcgtgaaca atttgcctgg ctgcgcgaga acggttatca
     2941 accggtcagt attgctcaaa ttcgtgaagc acatcgagga ggaaaaccgc taccggaaaa
     3001 agctgtagtg ctgacttttg atgacggcta ccagagtttt tatacccgcg tcttcccaat
     3061 tcttcaggcc ttccagtggc ctgctgtatg ggcccccgtc ggcagttggg tcgatacgcc
     3121 agcggataaa caagtaaaat ttggcgatga gttggtcgat cgagaatatt ttgccacgtg
     3181 gcaacaagtg cgagaagttg cgcgttcccg gctcgttgag ctcgcttctc atacatggaa
     3241 ttctcactac ggtattcagg ctaatgccac cggcagctta ttgcctgtat atgtaaatcg
     3301 tgcatatttt actgaccacg cacggtatga aaccgcagca gaataccggg aaagaattcg
     3361 tctggatgct gtaaaaatga cggaatacct gcgtacaaag gttgaggtaa atccacacgt
     3421 ttttgtttgg ccttatggcg aagcgaatgg catagcgata gaggaattaa aaaaactcgg
     3481 ttatgacatg ttcttcaccc ttgaatcagg tttggcaaat gcgtcgcaat tggattccat
     3541 tccgcgggta ttaatcgcca ataatccctc attaaaagag tttgcccagc aaattattac
     3601 cgtacaggaa aaatcaccac aacggataat gcatatcgat cttgattacg tttatgacga
     3661 aaacctccag caaatggatc gcaatattga tgtgctaatt cagcgggtga aagatatgca
     3721 aatatcaacc gtgtatttgc aggcatttgc tgatcccgat ggtgatgggc tggtcaaaga
     3781 ggtctggttt ccaaatcgtt tgctaccaat gaaagcagat atttttagtc gggttgcctg
     3841 gcaattacgt acccgctcag gtgtaaacat ctatgcgtgg atgccggtat taagctggga
     3901 tttagatccc acattaacgc gagtaaaata cttaccaaca ggggagaaaa aagcacaaat
     3961 tcatcctgaa caatatcacc gtctctctcc tttcgatgac agagtcagag cacaagttgg
     4021 catgttatat gaagatcttg ccggacatgc tgcttttgat ggcatattgt tccacgatga
     4081 tgctttgctt tcagattatg aagatgccag tgcaccggct atcacggctt atcagcaagc
     4141 aggctttagc gggagtctga gcgaaattcg acaaaacccg gagcaattta aacagtgggc
     4201 ccgctttaaa agtcgtgcgt taactgactt cactttagaa cttagtgcgc gcgtaaaagc
     4261 cattcgcggt ccacatatta aaactgcacg aaatattttt gcacttccgg taatacaacc
     4321 tgaaagtgaa gcctggtttg cacagaatta tgctgatttc ctaaaaagct atgactggac
     4381 cgctattatg gctatgcctt atctggaagg tgtcgcagaa aaatcggctg accaatggtt
     4441 aatacaattg accaatcaaa ttaaaaacat ccctcaggct aaagacaaat ctattttaga
     4501 attacaggca caaaactggc agaaaaatgg tcagcatcag gctatttctt cgcaacaact
     4561 cgctcactgg atgagcctat tacaactgaa tggagtgaaa aactatggtt attatcccga
     4621 caattttctg cataaccaac ctgaaataga ccttattcgt cctgagtttt caacagcctg
     4681 gtatccgaaa aatgattaat cgcatcgtat cgttttttat attatgtctg gtgttatgca
     4741 tacccctatg cgtagcgtac tttcactctg gtgaactgat gatgaggttc gttttcttct
     4801 ggccgttttt tatgtccatt atgtggattg ttggcggcgt ctatttctgg gtctatcgtg
     4861 aacgccactg gccgtgggga gaaaacgcac cagctcccca gttgaaagat aatccgtcta
     4921 tctccattat cattccctgt tttaatgagg agaaaaacgt tgaggaaacc atacacgccg
     4981 ctttagcaca gcgttatgag aacattgaag ttattgccgt aaatgacggt tcaacagata
     5041 aaacccgtgc catcctggat cgcatggctg cacaaattcc ccatttgcgg gtcattcatc
     5101 tggcgcaaaa ccaggggaaa gccattgcgc ttaaaaccgg agctgccgcg gcgaaaagtg
     5161 aatatctggt gtgcattgat ggcgatgcgt tattagaccg cgatgcggcg gcatatattg
     5221 tggaaccgat gttgtacaac ccgcgtgtgg gtgccgtaac cggtaatcct cgtattcgaa
     5281 cacgttctac cctggtgggt aaaattcagg ttggcgagta ttcctcaatt attggtttga
     5341 tcaagcgaac ccagcgtatc tatggaaacg tatttaccgt ttccggtgtt attgccgcat
     5401 ttcgtcgcag cgccctggca gaagtgggtt actggagtga cgatatgatc accgaagata
     5461 ttgatattag ctggaagctg cagttgaatc agtggacgat tttttacgag ccacgggcac
     5521 tgtgctggat attaatgcct gaaacgttaa aagggctgtg gaaacagcgc ctgcgctggg
     5581 ctcagggcgg tgcagaagta ttcctcaaaa atatgacaag gttgtggcgc aaagaaaact
     5641 ttcgaatgtg gccgctgttt tttgaatact gcctgacgac aatatgggcc ttcacctgcc
     5701 tggtcggttt cattatttac gcagtccaac ttgccggtgt accgttaaat attgaattga
     5761 cacatatcgc tgcgacacat actgccggaa tattattgtg tacgttatgt ttactgcaat
     5821 ttattgtcag cctgatgctc gagaatcgct atgagcataa tctgacttca tcgcttttct
     5881 ggattatttg gttcccggtt attttctgga tgctgagcct ggcaacgaca ttggtatcat
     5941 ttacacgagt catgttgatg cctaaaaagc aacgcgcccg ttgggtaagt cccgatcgcg
     6001 ggattctgag aggttaatat gaacaattta attattacga cccgacaatc accagtacgt
     6061 ttactggttg attatgttgc cacaaccatc ttgtggacat tatttgcgtt gttcatattc
     6121 ttattcgcca tggatctgct gacgggttat tactggcaaa gcgaggccag aagccgactt
     6181 cagttctatt ttttgctggc agtggcgaat gccgtcgtgt taattgtctg ggcgctgtac
     6241 aataagctgc gttttcaaaa acagcagcat catgcagcct accaatatac gccgcaagaa
     6301 tatgcagaga gcttagcaat acctgatgag ctctatcagc aactacaaaa aagccacagg
     6361 atgagcgtac acttcaccag ccaggggcaa ataaaaatgg ttgtttcaga aaaagcgcta
     6421 gtccgggcat aaacacccaa aacaaagccc ggttcgcccg ggctctgcac cgataacaca
     6481 cttaactgta ggcatgcagc gtacgttggc aaagtgccga acgtacgcag tcctctttac
     6541 cgaaccggac gatcccaacc atttcatctt cttcgaaacg ttccagcgcg tcacttaatc
     6601 cggagcacac gccgcgaggc aaatcgcatt gcgtgatatc accgttgacg ataaccgtca
     6661 cgttctcccc gaggcgggtt aaaaacattt tcatttgcgc ggcagtcaca ttctgcgcct
     6721 cgtcaagaat gacgactgca ttttcaaagg tacgtccacg catataggcg aacggcgcaa
     6781 tttccacctt ccctatttcc ggtcgcaggc agtactgcat aaaggaagcc cctaagcgcc
     6841 ggaccagcac gtcgtagacc gggcgaaaat agggagcaaa cttttctgcg atatctccag
     6901 gtaagaagcc aagatcttca tcggcttgca gaactggacg ggtgacgata atcctgtcga
     6961 catccttatg tatcagggcc tctgccgctt ttgctgcgct gatccaggtt tttccgcacc
     7021 cggcttcgcc cgtggcgaat atcagctgct tactctcaat agccttcaga tagtgcaatt
     7081 gcgcttcatt tcgcgcgagg atgggcgaag tatcgcgact gtcgcgggcc ataccaatgg
     7141 cttctacgcc gcccatctgc acaagcgagg tgaccgattc ttcttcacgc tgcttatggc
     7201 tgcgcgaatc ccgtctcagc acacgttttg cctcgcgacg agctttgatc actgcttttt
     7261 gtcttcccat ggagagcacc ttgagttgtt tgtattcatc acacgcgccg ttggcagcgc
     7321 gattatgcgc acgaacatca gagggttggc ttccttgtaa gccatagttt gcttttggat
     7381 aaaatgccga aaaacggcta cgcgcaccgt ttacggcgtc ggtaacacat gaaaagaaag
     7441 gatgaggttg aaaatgcaaa gtgacgagat gactaccgga ggagaaaact ccgcgagtgg
     7501 tggcgcgttg attatctaaa acatgtccag tacaggacgt taccatccgc gatctccata
     7561 gtgactgact atcactgccg ggaacttccg ctgctactta ataagtacaa cagatctcgc
     7621 atttattgca acaatatatt tacttatatt taactataaa acaccatttc agtgacatta
     7681 gtttctactg gaaagatgac agagtgatga cagtgatgaa aaaagctgtg tgctttcagc
     7741 aggatttgca tcaggcatca gtgcacgatc gccggatgcg gcgtgaacgc cttatccagc
     7801 ctaccaaacc cgcactgatt gtaggcatga taagacgcgc aagcgtcgca tcaggcatct
     7861 gcgcacaaat gccttatccg cctaaaaaca ttaaacccgc aataacgcgc ttccgaaata
     7921 atcgttcgcg tccttcaccc ccggcagcgc aaaaaaataa ccgccgccga taggtttaac
     7981 gtattcctcc agcgcttcgc cattgagcct tttttgtact gtcaggaagc ctttttccag
     8041 atcgtgttgg tagcagacaa acagcaaccc catatccagt tgcccggagt tggtgacgcc
     8101 cagtgaataa ctgtagccac gacgcagcat caggctggac tcactctccg ccgtgcgggg
     8161 attcgccagc cggatatggc tgtccagcgc gatcaccttc ccttccgggt cgctggcgta
     8221 atcaggcaca tcatgctcat gctgcattcc cagcggcgca ccggtttgct tatcacggcc
     8281 aaaaatcgtc tgctgttctt tcagcggcgt tctgtcccaa aattccactc gaaactgaat
     8341 caagcgtact gcctgatagc tgccaccgat tgtccacgca ggctcctgct gatctgccgt
     8401 tacccacacc actttttgca tcaacttatc attctggcta tcgggattgg cagtgccgtc
     8461 tttgaaaccc agcaaattaa tcggcgtctc tttgccttta ctacgcgccg cgtgatcgga
     8521 aataaaccct tcccgcttcc agcgcacact gagcaaatcc ggcgtgtgtt tgatgatatc
     8581 gcgcagcgca tggataaccg tgtcctgggt gttggcgcaa atctgtagca acacatcacc
     8641 atgacataac gccgcatcca gcgagtcgtt ggggaaacgc gtcatcttct gcagcttttt
     8701 tggcatctgt ggcgcaaggc caaagcgctc atcaaacaat gagtgaccca ccgataacgt
     8761 gatggtgaga ttatcgggcg caatgtagcc gccaagaatg ccggaatcga gtggtggcag
     8821 gcgcggattt ggcgtttctg gtgctgctcc gccctgagtc agaaaagcaa aacgctgagt
     8881 caacaagcga aacaaccgct caagatcggc tttatcgctg gcaagcacat caaacgccac
     8941 cagcatcatt gcggcctgtt gtggcgtcag gatccctgcc tgatgctcac cataaaacgg
     9001 ctgtttctca ttgcgagcat ccggtgaaag cgtacccggc gcactttgcg ttttttgtgc
     9061 atgagcgacc ggacaacttc ccgccagcgc cagtgcacct atcactttca gtaaacgtcg
     9121 gcgtgacggt tcattcacgc cgttttcatc tttatactgc ataacgctta atccagtccc
     9181 agcacaccgc gaagttgcgc cagatcttcc gccagcgcag taatcggtcc tttcagtgca
     9241 ttccggtcgg catcggtcaa tttgtcgtag gtttcaaaac cgtctttagt acggtatttc
     9301 gccagaatgg tatcgacctt tttaaagttg gcatcgactt ttgccagcag ttccgggttg
     9361 gctttttgca gttgtggacg cagcaaatcg acaattttct gcgagccttc aacgttagcc
     9421 tggaaatccc acagatcggt gtggctgtag cgatcttctt caccgctaat tttgctggct
     9481 gccacttcct caatcagtcc ggctgcgccg ccgaccactt ttgaaggtgg gaaagccagt
     9541 tcactgatgc gtttttgcaa atcgaccaca tcggtataaa gctgctcagc gtactgatcc
     9601 atccctttgg tggtgttgtc gccaaacaat gctttttcca gacggtggaa accagtgaat
     9661 tttgggtcgg cggctttttg ctcgtaatca tcttcacggg cgtcaatgct gccatccaga
     9721 tcggagaaca gttcagcaat cggttcaata cgctcatagt gctggcgcgt cggtgcatac
     9781 agtgctttcg ctttttcgat atcgcctgct ttaatcgcgt cggtaaaggc tttggtgtcg
     9841 gtcaccagct gcgtggtttc cgccatgaca tacgctttat atgcagtaat tgcaccacca
     9901 agacttaaca gcgcatcact ttgcgccgca tccgccgttg cctcaccttt gacgatcaac
     9961 ttccctttcg ggttagtcag cagaccgcag gtcatatcgt attcgccagg ctgtaaattc
    10021 gccgtcattt tctggctaaa gccaggggcg atattttccc gctcttccac caccatcacg
    10081 cctttgagga tctcccactc cagcgccttc tggctgtggt tctgaataat gaactgtgtt
    10141 ttcccggcgt taaccgtaat ggtcatcggt tcgcactgct tatccgtcac ggtcactttg
    10201 acctgcggca catcagcggc gttagccata aaagcagaag aaaacagcgc agccacgctc
    10261 aactgcaatg cgttacggcg gaagttaatg gtcatgacga gactatccct ttaaagtatg
    10321 ttgtaactaa gcaagagttt gcgtcgtatt tgttacgcgg agcgagacgc tgtcgcccct
    10381 gcgcgtggtg gcagagcaaa tgccaccagc gccgggatga gataaataaa ccagacggcg
    10441 acttcgctga cgctcggcgc ttcctgatag ccaaaaatcc cttccatcag cgtgccaaac
    10501 agcgagtgag ttgagagcac cgcactcata tcgaaggcga tttcctgaaa gtggttccac
    10561 aatccggctt catgaaatgc gcgaatggca ccagctgcca gccctgcggc gacgaagaga
    10621 ataaacaggc tggtccattt aaaaaatgca ccaagattga ggcgaatacc gccccagtag
    10681 agcaggaagc ctagcaccac ggcagtagca agaccgagca ttgcacccag cggcggccag
    10741 atcccgacat cttgttgaaa tgccgccagc aggaaaaaga ccgactccag cccttccctt
    10801 gcaacggcaa aaaagaccat catcaccagc gcccagccat gatgatttcc acgctgcaat
    10861 gcgctatcga ctgcctgttc cagttgcact ttgacgttgc gcgacacttt gcgcatccag
    10921 aaaaccatcc aggtaaggat caccacggcg atcaccgcca cgataccttc aaacagttcc
    10981 tgttcttttt gcggaaattc gccggtggtt tcgttaatga agatacccaa gcccaggcac
    11041 aacgcagcgg caagcaacac gccaatccac atcacaccaa tccatcggcc tcgctgggta
    11101 cgcttaagat agctggcaat caaactgaca atcagcgcgg cttcaagtcc ttcgcgcaac
    11161 ataatgagaa acggaacaaa catgccaccc acccttaaac gtttttctga gtcaatctat
    11221 gcaaagaaaa gtaaatcgca gtgatagcga ttatcattac agcaaagaaa aacacaagcg
    11281 gaatgtttat aaaatgatgt tggaatgtaa acaaagagag gtaatgccaa gggatataaa
    11341 cgattattcc agggtagaaa gatgggattg tttgcaaaga accatgtgtt cttgccggat
    11401 gccgcgtaaa cgccgtatcc agccgacaaa actgtccaga ctcaatgcat cagagcttcc
    11461 atgtaaaact gataagcggg tgtatcaagc aatttcgtcc atccgcgatt atcaaatcta
    11521 actttttgcc cggaacataa taacagctcg ggtgttggtg gcgtcaaaat cgctgaagcg
    11581 ttccccgaag gccgggacag cagggggcgg cggcgattgg ccgccccctg cgcgctccct
    11641 gcaccattca atttatatgg cgaggcacat taagggagcg caacccgctg ctgaagccaa
    11701 acaaaaccgc cgcaggctaa gtcccttagc tttcctgcaa ccgtgacggc ggagccgaat
    11761 gatagtgcgc atcggcctcg gcaaagcgtt tttgcatcgc cgctgacggc gctttaccca
    11821 gcaaactaaa cactacaatc ccaatactgc cgaagataaa gcccggaata atttcgtaca
    11881 gtcccagcca gccgaactgt ttccagacga taaccgtcag cgcaccgatg atcatccccg
    11941 ccagcgcacc gttacgcgtc atgcgtgacc acatcaccga gaacagcacc actggaccaa
    12001 acgccgcgcc aaagcctgcc cacgcgtagc tcactaagcc cagcacgcgg ttttccgggt
    12061 ttgccgccag cgcaatcgcc accagcgcca ccaccagcac catcacacgc cctacccaca
    12121 ccagctcttt ctggctggca tgtttacgca gaaacgcttt gtacaaatct tcggtaatcg
    12181 cactggagca caccagcagc tggcaactta aggttgacat taccgccgcc agaattgccg
    12241 acagcagaat cccggcaatc cacgggttaa acagaatttg cgccagttcg ataaacacac
    12301 gctcggcgtt ctgatttacc gcaccagcca acgccggatg atcgttaaag taagcaatcc
    12361 caaagaagcc gacagccacc gcccctgcca ggcagaggat catccaggtc atactaatac
    12421 gacgcgcatg gacaatgctg tggtgagaat ccgccgccat aaaacgcgcc agaatgtgcg
    12481 gctgcccgaa gtaacccagc ccccaaccca tcagtgagat aatggcaaca aagttcagac
    12541 ctttgagcat atcaacgttt tcgatgctct tttgtttgat cacttccagc gagtcaccaa
    12601 agccaccgac actgataatg acgataaccg gcgtcaggat cagggcaaaa atcatcaggc
    12661 tggcctgtac agtgtcagtc cagctcaccg cgaggaaacc gccaataaag gtgtaaagga
    12721 tcgtcgccgc agcgcccgcc cacagagccg tttcgtagct catgccaaag gtactttcaa
    12781 acagacgcgc gcctgccaca atgcccgaag cgcaataaat ggtgaagaac agcaaaataa
    12841 ccagcgcaga gataatgcgc aaaatgcggc ttttatcttc aaagcgcccg gtgaaataat
    12901 ccggcagtgt taaggcgtta ttgttgtatt cggtatgcac acgcaaccgc ccggccacca
    12961 gcttccagtt aatccacgcg cctaatgtca ggccaatggc gatccagctt tcggaaatcc
    13021 cggaaagaaa aacagcgccc ggcaacccca ttaacagcca gccgctcata tccgacgcac
    13081 ccgccgataa tgccgtcacg aatggcccaa gactacgacc gcccagaata tagtcgtcaa
    13141 agtttttcgt tgatcgccag gcgataaacc caatcaatat catgccaaag atatagacac
    13201 aaaatgtcac caacatcggt gtgctaatag ccatctaaag tctccaaaaa attattatcg
    13261 gcaatgtcga aacttgccgt tatatctgcc accggaacgg ggtaacagag tttatgtttt
    13321 accagggcga ccgtatcctg ccggaagcgc tggttattca caatcgattt aacacaccat
    13381 ttacattaaa ttttagtgct cagcgacact atttttcatc aggttgcact ctctcacatt
    13441 ttttgcggtt gcacctttca aaaatgttaa ctgccgcaga gaaaaagtct gagttatttt
    13501 tttaatccct gtcatatcga tttcttttat taacatttca ttcattttta agcttgctac
    13561 gcatgtcaca tttaacatgg ttgcacaaag ttgcaacatc atggatattt cacgataacg
    13621 ttaagttgca cctttctgaa caacaggagt aatggcatgg gaaccaccac catgggggtt
    13681 aagctggacg acgcgacgcg tgagcgtatt aagtctgccg cgacacgtat cgatcgcaca
    13741 ccacactggt taattaagca ggcgattttt tcttatctcg aacaactgga aaacagcgat
    13801 actctgccgg agctacctgc gctgctttct ggcgcggcca atgagagcga tgaagcaccg
    13861 actccggcag aggaaccaca ccagccattc ctcgactttg ccgagcaaat attgccccag
    13921 tcggtttccc gcgccgcgat caccgcggcc tatcgccgcc cggaaaccga agcggtttct
    13981 atgctgctgg aacaagcccg cctgccgcag ccagttgctg aacaggcgca caaactggcg
    14041 tatcagctgg ccgataaact gcgtaatcaa aaaaatgcca gtggtcgcgc aggtatggtc
    14101 caggggttat tgcaggagtt ttcgctgtca tcgcaggaag gcgtggcgct gatgtgtctg
    14161 gcggaagcgt tgttgcgtat tcccgacaaa gccacccgcg acgcgttaat tcgcgacaaa
    14221 atcagcaacg gtaactggca gtcacacatt ggtcgtagcc cgtcactgtt tgttaatgcc
    14281 gccacctggg ggctgctgtt tactggcaaa ctggtttcca cccataacga agccagcctc
    14341 tcccgctcgc tgaaccgcat tatcggtaaa agcggtgagc cgctgatccg caaaggtgtg
    14401 gatatggcga tgcgcctgat gggtgagcag ttcgtcactg gcgaaaccat cgcggaagcg
    14461 ttagccaatg cccgcaagct ggaagagaaa ggtttccgtt actcttacga tatgctgggc
    14521 gaagccgcgc tgaccgccgc agatgcacag gcgtatatgg tttcctatca gcaggcgatt
    14581 cacgccatcg gtaaagcgtc taacggtcgt ggcatctatg aagggccggg catttcaatc
    14641 aaactgtcgg cgctgcatcc gcgttatagc cgcgcccagt atgaccgggt aatggaagag
    14701 ctttacccgc gtctgaaatc actcaccctg ctggcgcgtc agtacgatat tggtatcaac
    14761 attgacgccg aagagtccga tcgcctggag atctccctcg atctgctgga aaaactctgt
    14821 ttcgagccgg aactggcagg ctggaacggc atcggttttg ttattcaggc ttatcaaaaa
    14881 cgctgcccgt tggtgatcga ttacctgatt gatctcgcca cccgcagccg tcgccgtctg
    14941 atgattcgcc tggtgaaagg cgcgtactgg gatagtgaaa ttaagcgtgc gcagatggac
    15001 ggccttgaag gttatccggt ttatacccgc aaggtgtata ccgacgtttc ttatctcgcc
    15061 tgtgcgaaaa agctgctggc ggtgccgaat ctaatctacc cgcagttcgc gacgcacaac
    15121 gcccatacgc tggcggcgat ttatcaactg gcggggcaga actactaccc gggtcagtac
    15181 gagttccagt gcctgcatgg tatgggcgag ccactgtatg agcaggtcac cgggaaagtt
    15241 gccgacggca aacttaaccg tccgtgtcgt atttatgctc cggttggcac acatgaaacg
    15301 ctgttggcgt atctggtgcg tcgcctgctg gaaaacggtg ctaacacctc gtttgttaac
    15361 cgtattgccg acacctcttt gccactggat gaactggtcg ccgatccggt cactgctgta
    15421 gaaaaactgg cgcaacagga agggcaaact ggattaccgc atccgaaaat tcccctgccg
    15481 cgcgatcttt acggtcacgg gcgcgacaac tcggcagggc tggatctcgc taacgaacac
    15541 cgcctggcct cgctctcctc tgccctgctc aatagtgcac tgcaaaaatg gcaggccttg
    15601 ccaatgctgg aacaaccggt agcggcaggt gagatgtcgc ccgttattaa ccctgcggaa
    15661 ccgaaagata ttgtgggcta tgtgcgtgaa gccacgccgc gtgaagtaga acaggcgctg
    15721 gaaagtgcgg ttaataacgc gccaatctgg tttgccacgc ctccggctga acgcgcagcg
    15781 attttgcacc gcgctgccgt gctgatggaa agccagatgc agcaactgat tggtattctg
    15841 gtgcgtgagg ccggaaaaac cttcagtaac gccattgccg aagtgcgcga agcggtcgat
    15901 tttctccact actacgccgg acaggtgcgg gatgatttcg ctaacgaaac ccaccgtcca
    15961 ttagggcctg tggtgtgtat cagtccgtgg aacttcccgc tggctatttt caccgggcag
    16021 atcgccgccg cactggcggc aggtaacagc gtgctggcaa aaccggcaga acaaacgccg
    16081 ctgattgccg cgcaagggat cgccattttg ctggaagcgg gtgtaccgcc aggcgtggtg
    16141 caattgctgc caggtcgggg tgaaaccgtg ggcgcacaac tgacgggtga tgatcgcgtg
    16201 cgcggggtga tttttaccgg ttcaaccgaa gtcgctacgt tactgcagcg caatatcgcc
    16261 agccgcctgg acgctcaggg tcgccctatt ccgctcatcg ctgaaaccgg cggcatgaac
    16321 gcgatgattg tcgattcttc agcactgacc gaacaggtcg tcgtggatgt actggcctcg
    16381 gcgttcgaca gtgcgggtca gcgttgttcg gcgctgcgcg tgctgtgcct gcaagatgag
    16441 attgccgacc acacgttgaa aatgctgcgc ggcgcaatgg ccgaatgccg gatgggtaat
    16501 ccgggtcgcc tgaccaccga tatcggtcca gtgattgata gcgaagcgaa agccaatatt
    16561 gagcgccata ttcagaccat gcgtagcaaa ggccgtccgg tgttccaggc ggtgcgggaa
    16621 aacagcgaag atgcccgtga atggcaaagc ggcacctttg tcgccccgac gctgatcgaa
    16681 ctggatgact ttgccgaatt gcaaaaagag gtctttggtc cggtgctgca tgtggtgcgt
    16741 tacaaccgta accagctacc agagctgatc gagcagatta acgcttccgg ttatggtctg
    16801 acgcttggcg tccatacgcg cattgatgaa accatcgccc aggtcactgg ctcggcccat
    16861 gttggtaacc tgtatgttaa ccgtaatatg gtgggcgcag tggttggtgt gcagccgttc
    16921 ggcggcgaag ggttgtccgg taccgggccg aaagcaggcg gtccgctcta tctctaccgt
    16981 ctgctggcga atcgcccgga aagtgcgctg gcagtgacgc tcgcgcgtca ggatgcaaag
    17041 tatccggtcg atgcgcagtt gaaagccgca ttgactcagc cgctaaatgc actgcgggaa
    17101 tgggcagcaa atcgtccaga attgcaggcg ttatgtacgc aatatggcga gctggcgcag
    17161 gcaggaacac aacgattgct gccggggccg acgggtgaac gcaacacctg gacgctgctg
    17221 ccgcgtgagc gcgtgttgtg tattgccgat gatgagcagg atgcgctgac tcagctcgcc
    17281 gccgtgctgg cggtgggcag ccaggtactg tggccggatg acgcgctgca tcgtcagtta
    17341 gtgaaggcat tgccatcggc agtcagcgaa cgtattcaac tggcgaaagc ggaaaatata
    17401 accgctcaac cgtttgatgc ggtgatcttc cacggtgatt cggatcagct tcgcgcattg
    17461 tgtgaagcag ttgccgcgcg ggatggcaca attgtttcgg tgcagggttt tgcccgtggc
    17521 gaaagcaata tccttctgga acggctgtat atcgagcgtt cgctgagtgt gaataccgct
    17581 gccgctggcg gtaacgccag cttaatgact ataggttaaa caggtagccg gaggatgtta
    17641 caacctcctc cggcatcttt aacgtggtcg aatcccctca ataataatcc gctgcacgtt
    17701 ttcaaccgtt tgattgaaaa atacctcatc gcgcaacgtc gcgcctgtca ccgcctccac
    17761 ctgaggggcg aaatcggcgt aatgttgagt ggaagcccaa atcataaaaa tcaaatgctg
    17821 cggatcaatc ggcgcgagtt tgccgctttt gacccaaccg gcaatcagcg ccgatttctc
    17881 atcaattaat gccttcaaat cgcccgtcag ttcatccatt aacagcggcg cgcctgccag
    17941 catctccata cagaacaggc gcgaagcctg cggataatcg cgtgagactt ccagcttcag
    18001 acggatgtac tctttgatcg ccgccagcgg ggcgaaatct tcacgaaacg cttttaacgg
    18061 tgccagccag atatcgagaa tctgccgcag cacggcaata tacagcgcct cttttgacgg
    18121 aaagtaatac agcagattgg tttttgaaac acccgccaac tctgcgatct gctccagcct
    18181 tgtgccgtga aaaccgaatt gtgaaaaagt gtccagtgct gcgctaagaa tcgctttttt
    18241 cttcgcgctt actgcgcgcg aacgtttacc cgttgttttc actgcgcctt gcgtcatgcg
    18301 ctctcccctc ttgtagattg gcaacaggat agcaaaaccc ccgcccggcc tcgaccttct
    18361 gcactctcat cgcgcacaga tgcatgtttt atgtgcaact gttttgaccg tttagtccac
    18421 tttttaccag atattttaga taacgtaatg ttaacagatt aataacatta actttttaaa
    18481 aactggcatc cgctttgcaa acaagccaat acgcggctga aaaggatatg caggatgcag
    18541 cgccccgtct gactttcact ttacgagacg aagagaggtt gatgatgaaa attggcgtat
    18601 tcgtacctat tggcaacaac ggctggctca tttcgaccca cgcgccgcag tacatgccga
    18661 cctttgaact gaataaagcc attgtgcaaa aagcggagca ctaccatttc gatttcgccc
    18721 tgtcgatgat caaactgcgt ggctttggcg gcaaaactga gttctgggat cacaaccttg
    18781 agtcgttcac cttgatggcg gggctggcgg ccgtgacctc gcgcattcag atttacgcca
    18841 ctgctgccac cttaacgtta cctccggcaa tcgtcgcccg tatggccgca accatcgact
    18901 ccatctctgg cgggcgtttt ggcgtcaacc tcgtgactgg ctggcaaaag cccgagtatg
    18961 agcagatggg tatctggcct ggcgatgact atttctcccg tcgttacgac tatctcaccg
    19021 aatatgttca ggtgctgcgc gacctgtggg gcacggggaa aagcgatttt aaaggcgatt
    19081 ttttcaccat gaatgattgt cgcgtgagtc cgcaaccgag tgtccccatg aaagtgatct
    19141 gcgccgggca aagcgacgct ggcatggcgt tctccgcccg gtatgccgat ttcaacttct
    19201 gtttcggcaa aggcgtaaat acacccacgg ctttcgcccc gaccgctgcg cggatgaaac
    19261 aggccgcaga gcaaaccgga cgcgacgttg gctcttatgt gttgtttatg gtgattgccg
    19321 atgaaaccga cgatgccgct cgcgccaaat gggaacacta caaagcgggc gcggatgaag
    19381 aggcgttaag ctggctaacc gaacaaagtc agaaagatac ccgctccggt actgacacca
    19441 acgttcgtca gatggccgat cccacttcgg cggtaaacat caatatgggg acgttagtcg
    19501 gttcttacgc cagtgtcgcg cgcatgttag atgaagtcgc aagcgtgcct ggtgccgaag
    19561 gcgtgctgtt aaccttcgac gattttctgt cgggaatcga aaccttcggc gagcgcattc
    19621 aaccactgat gcaatgccgc gcccatctac ctgcgctgac tcaggaggtg gcatgatgac
    19681 gaccttaacc gctcgaccgg aagccattac cttcgatccg cagcaaagtg cgctgatcgt
    19741 ggtggatatg caaaacgctt atgccacgcc aggcggctac ttagatctcg ccgggtttga
    19801 tgtctcaacc actcgcccgg tcattgccaa cattcaaacc gccgtgaccg cagcgcgagc
    19861 ggcagggatg ctgatcatct ggtttcaaaa tggctgggat gaacagtatg tcgaggctgg
    19921 cggacccggc tcaccgaatt ttcataaatc gaacgccctg aaaaccatgc gtaagcagcc
    19981 gcagctgcag gggaaattgc tggcgaaagg ctcctgggat tatcaactgg tggatgaact
    20041 ggtgccgcag cctggcgata ttgtgctgcc gaagccgcgc tacagcggtt tcttcaatac
    20101 gccgctggac agcattttgc gcagccgcgg aatacgccat ctggttttca ccggcatcgc
    20161 taccaacgtc tgcgtcgaat cgacgctacg cgacggcttt tttctggagt atttcggcgt
    20221 ggtgcttgaa gacgcaactc accaggcggg gccgaaattt gcgcagaaag ccgcgttgtt
    20281 caatatcgaa accttttttg gctgggtcag cgacgtcgaa acattctgcg acgcgctttc
    20341 tcccacgtcc tttgctcata tcgcttaagg agtttaacga tgccaaaatc cgtaattatt
    20401 cccgctggca gcagcgcacc gctggccccc ttcgttcccg gcacgctggc tgatggcgtg
    20461 gtgtatgtct ccggtacgct ggcttttgat caacataata acgtgctgtt tgccgatgac
    20521 ccaaaggcgc aaacccgcca cgttctggaa actatccgca aggtgatcga gacggcgggt
    20581 ggcacgatgg cggatgtgac cttcaacagc atctttatta ccgactggaa aaattacgcc
    20641 gcgattaacg aaatctacgc cgagtttttt ccgggtgata aaccggcgcg attctgcatt
    20701 cagtgcggac tggtaaaacc tgacgcgctg gtggaaatcg ccacaattgc gcatatcgcc
    20761 aagtgaggcc gcgatgaaac tttcactctc acctccccct tatgctgatg cgcccgtagt
    20821 ggtgttgatt tcgggtcttg ggggtagcgg cagttactgg ttaccgcaac tggcggtgct
    20881 ggagcaggag tatcaggtag tctgttacga ccagcgcggc accggcaata atcccgacac
    20941 gctggcagaa gattacagta tcgcccagat ggcagcggaa ctgcatcagg cgctggtagc
    21001 cgcagggatt gagcattacg cagtggtcgg ccatgcgctc ggtgcgctgg tgggaatgca
    21061 gctggcgctg gattatcccg cgtcggtaac tgtgctgatc agcgttaacg gctggctacg
    21121 aataaacgcc catacgcgcc gctgttttca ggttcgcgaa cgattactgt atagcggcgg
    21181 cgcgcaggca tgggtggaag cgcagccgtt gttcctctat cccgccgact ggatggcggc
    21241 ccgcgcacct cgcctggagg cagaagacgc gctggcactg gcgcattttc agggcaaaaa
    21301 taatttactg cgtcgactta acgccctcaa acgcgctgac tttagtcacc atgcggatcg
    21361 catccgctgc ccggtgcaaa tcatctgcgc cagtgatgat ctgctggtgc caacagcatg
    21421 ttccagtgaa cttcatgccg ccctgcccga tagccagaaa atggtgatgc cctatggcgg
    21481 acacgcctgc aacgtgaccg atcccgaaac gtttaatgct ctgttactca acgggcttgc
    21541 cagcctgtta catcaccgtg aagccgccct gtaaggaatt gctatgaacg aagccgttag
    21601 cccaggtgcg cttagcaccc tgttcaccga tgcccgcact cacaacggct ggcgggagac
    21661 acccgtcagc gatgagacgt tacgggagat ttatgccctg atgaaatggg ggccgacatc
    21721 agctaactgt tctccggcac ggatcgtgtt tacccgcacg gcagaaggaa aagaacgtct
    21781 gcgcccggca ctttccagcg gcaatctgca aaaaaccctg accgcgcccg tcaccgctat
    21841 cgtcgcctgg gacagtgaat tttatgaacg gttaccacta ctgtttcccc acggtgatgc
    21901 ccgcagttgg tttacctcca gcccacaact tgccgaagaa acagcgtttc gcaacagttc
    21961 catgcaggcg gcctatctga tcgtcgcctg ccgggcgctg ggactggata ccggcccgat
    22021 gtcgggcttt gaccgtcaac acgtggacga cgcctttttt acgggcagca cgctgaagag
    22081 caatctgctg attaatatcg gctatggcga tagcagcaag ctttatgcgc gcctgccacg
    22141 tctgtccttt gaagaagcct gcgggctgtt gtaaggagca aactatgaac attgtcgatc
    22201 aacaaacttt tcgcgatgcg atgtcctgca tgggcgcggc ggtcaatatt atcaccacgg
    22261 acggtccagc cgggcgcgcc gggttcaccg ccagcgccgt ctgcagtgtg accgatacgc
    22321 cgcccacatt actggtgtgc ctgaatcgtg gggcgtccgt ctggccggca ttcaatgaaa
    22381 atcgaacgct gtgtgtaaat acacttagcg ccgggcagga gccgctttca aacctttttg
    22441 gcggcaaaac gcccatggaa caccgctttg ccgccgcccg ctggcagacg ggggtgaccg
    22501 gatgcccgca actggaagag gctctggttt cgtttgactg ccgtatcagc caggtggtga
    22561 gcgtcggcac ccacgacatt ctgttttgcg ccatcgaagc gattcatcgt cacaccacac
    22621 cctacgggct ggtgtggttc gatcgcagtt atcacgcgct gatgcgccct gcttgttaac
    22681 ctccttaagg agacagctga tggcaatgtt cggttttcct cactggcagt taaaatcgac
    22741 ctctacagag agcggcgtgg tcgcgccgga tgaacgattg ccgtttgctc agacggcagt
    22801 aatgggcgtt caacacgcgg tggcgatgtt tggcgcgacg gtgttaatgc cgattctgat
    22861 ggggctggat cccaatcttt ccattttaat gtcggggatc ggcacgttac tgtttttctt
    22921 tattaccggc gggcgcgtcc ccagttatct cggctccagc gcggcttttg tcggcgtggt
    22981 gatcgccgcg acgggcttta acggtcaggg cattaacccg aatatcagca ttgcgctggg
    23041 cgggattatc gcctgtgggc tggtttatac cgtcattggc ctggtggtga tgaaaatcgg
    23101 tacgcgctgg attgaacgac tgatgccgcc ggtggtgacg ggtgcggtgg tgatggcgat
    23161 tggcctgaac ttagcgccta tcgcagtgaa aagtgtatcg gcttcggcct ttgatagctg
    23221 gatggcggta atgacggtgc tgtgtattgg gctggtggcg gtgtttaccc gtggcatgat
    23281 ccagcggtta ttgattctcg taggattaat tgtcgcctgt ctgctgtatg gcgtgatgac
    23341 caacgtttta gggctgggaa aagccgtcga ttttactctc gtcagccatg ctgcctggtt
    23401 cggtctgcca catttttcca ctcctgcttt taatggtcag gcaatgatgc tgattgcgcc
    23461 cgtggcggtg attctggtgg cggaaaactt aggtcatctc aaggcagtcg ccgggatgac
    23521 cggacgcaat atggacccgt atatggggcg ggcattcgta ggcgatggtc tggcaacgat
    23581 gctttccggc tctgtcggcg gtagcggcgt gaccacctat gctgaaaata tcggtgtgat
    23641 ggccgtgacc aaagtctact cgacgctggt gtttgttgct gctgccgtca tcgccatgct
    23701 gttgggcttt tcaccgaaat ttggtgcgct gattcatacc attccggccg cggttattgg
    23761 tggtgcatca attgttgtgt tcgggctgat tgccgtcgca ggcgcaagga tatgggtaca
    23821 aaaccgtgtc gatttaagcc agaacggtaa tttgattatg gtcgcagtaa ccttagtgct
    23881 gggcgcgggt gattttgctc tcacgctggg cggttttacg ttgggaggga ttggtacagc
    23941 aacctttggc gcgattttac tcaatgcgtt gttaagcaga aagttggttg acgttccacc
    24001 gccagaagtt gttcatcagg agccataaac agaaaaccgc cggggttacc ggcggtgcag
    24061 attgttgaca acgtacgcat tgttcatgcc ggatgcggcg taaacgcctt atccggccta
    24121 caaaacagtg caaattcaat atattgcaat cttctggtag gcctgataag catcgcgcat
    24181 caggcaagct tacatttgtc atcagtatca accaccgggt aaccggcggt gatggctttt
    24241 tgacgagcta cagacaaaaa tgcattcgtc attgattagc ccggctagtt gtcgcttttg
    24301 ccgtgactgc tcttaccacc ttttttacct gcttcagatg cgcgctgcgg gtcattcttg
    24361 aaattacccc cgctgtgctg tccacctttt ttacctgctt ctgatgctct ttcgcggtct
    24421 tctgcaaaat tgccggaacc gcctcgatgg tttgccatta ctgacctccg tctgggtata
    24481 gacatcatat tgcatagaat taacgcggcg tatggcggct gccatatttt cgctacgtgg
    24541 gactaagctt agtgaactga cgcgggcaga cccgcgtttg gtaatatcct gcaacagctt
    24601 cttagcgaga atagatatca tctccaataa ttatccataa gccgctctta tgattaaaaa
    24661 aacgcgatga gataaaaatg tgtcattttg cgacaaaatt acgtgcttgt gaaagttgtt
    24721 ataaatcaaa taagtggttg tgaaatttgc actctgaaaa ggacgtctta tctttaaata
    24781 agtggtagcg aatcgctacg gaatagagat aacacgagga gtggttagaa atggctaaag
    24841 ttctggtgct ttattattcc atgtacggac atattgaaac gatggcacgc gcagtcgctg
    24901 agggtgcaag caaagtggat ggcgctgaag ttgtcgttaa gcgtgtaccg gaaaccatgc
    24961 cgccgcaatt atttgaaaaa gcaggcggta aaacgcaaac tgcaccggtt gcaaccccgc
    25021 aagaactggc cgattacgac gccattattt ttggtacacc tacccgcttt ggcaacatgt
    25081 ccggtcaaat gcgtaccttc ctcgaccaga cgggcggcct gtgggcttcc ggcgcactat
    25141 acggaaaact ggcgagcgtc tttagttcca ccggtactgg cggcggtcag gaacaaacca
    25201 tcacatccac ctggacgacc cttgcgcatc acggcatggt aattgtccct attggctacg
    25261 cagcgcagga attatttgac gtttcacagg ttcgcggcgg tacgccgtac ggcgcaacca
    25321 ccatcgcagg cggtgacggt tcacgccagc ccagccagga agaactgtct attgctcgtt
    25381 atcaagggga atatgtcgca ggtctggcag ttaaacttaa cggctaatct tcaacaggag
    25441 gatacgcatg ccaactcaag aagcgaaagc tcatcacgtc ggtgaatggg catctctgcg
    25501 caatacgtcg ccggaaatag ccgaggccat tttcgaagtc gccgggtacg acgaaaaaat
    25561 ggcggaaaag atttgggaag aaggtagtga tgaagtgtta gtcaaagcct ttgctaagac
    25621 cgataaagat tcgctttttt ggggcgaaca gaccatcgaa cgtaaaaacg tttaaccagc
    25681 gactcccccg cttctcgcgg gggagttttc tgttatttca ccgcttcatt caacacgcta
    25741 tcaaacttat ccatcgggca gaaaccatca gcgtctatcg ggcaaccgct taattccagc
    25801 gtcacacgct gcgcaggtgc ctgcagggtt aacgcatcgg cattacgtaa ctgttccgca
    25861 ctctgataca catattcaat tttcatcaaa tcgcgattgg ctttgctgtc atgccaacgc
    25921 tggaaaacga ttttgccgcc aatcggcgtg cgttcgttct ggtcatgcaa ctgatacggt
    25981 ttgaaatcca gcgccgttaa cagagaggca atgttggagt cgtgcccaac caacactgta
    26041 attttcggtg cgctggtgcg atcggtgacc agagctttgt cgatataact gaccagcggt
    26101 ttcgcaacat tgcgcgccac ttccggtgag gtaaacaggc tgtcctggta gccgttttta
    26161 agcttcgaca acaccttcca ctgctggtca gatttgattt ctccccaggc cacctgatcc
    26221 atcggaaaac cttcgtaata ttgcaaagta aacgcatcta ccagcgagtt gccgactttc
    26281 agcggcccgg aaacacctgg ttcttgttga tacttggcgc taaaggtatt tttgccatcc
    26341 accagcgaac actgttgttt ctctttacag gcaggggaat ctttatagtt aacgattttt
    26401 tccagtagct ggtagctgtc ggtaagctgg agtttgctga gctctttctc cattgccgcc
    26461 accgcctgtt cactgaatgc ggcggaatca tcggtgatca ccgggttaaa ggttgggtcc
    26521 atagtgccca ttttttcctg gtgatgcaca ggaatatcac accccgggaa tgcgccggta
    26581 ataaagaact gtgcggtcgc aacggtacgt tgcagactat tggcataggc ataaacggtg
    26641 tacggcggcg ggcattcccc cgatttcacc atcccctgct ctgccagcca ttcacgcatg
    26701 taatggccca tatacacttc gagcacgcca cctttggtgg tgagttgccc accggggacg
    26761 tcccattctg gccatttatt cggcgtcgac tgctccagca cactgccatt gttcgccagc
    26821 ggcgcacgta agttatggcg gctcatcatg agcacttgct gtagctgata gccttccggt
    26881 acggtttgtg cctgagcgtt tgaagcgagt aaaactatcc ctgccacagc tgcggcgatt
    26941 agcgttttgt tcattcctgg cacctctttt gttatcaatc actaaagagt gtgacagaaa
    27001 tatgactttt ttccgggaac aggttcgcaa aatggcttgt tgaacgcctg tttttctata
    27061 tacatcttca aaaacaggca aggtttgacg caaactatgc ctgattagcc cctgcctcgc
    27121 gtacgccgct gataattgca cctgtggcta aacagaatat ctgcggcgtt accaatacag
    27181 agacaatatt taccaataaa aaagtgtgag actaataaca atggttttta gcatatgcct
    27241 ttgccattaa attgcataac gatttaaata gtcgagttgc gcattcattt ccttattgtt
    27301 taacttgtaa gcctgagcaa aaagttcagg agggaggtaa acgtcataat gattgccagt
    27361 gttcattaaa taaccatact caagatcttc atctgttgaa aaggattcat tccccaagga
    27421 gattgatgcc acattactat taacaataaa taatgagcaa atgctatctg aaagaacagc
    27481 aagaaaattc ttcaccgctt taatcctatc cgacgtgtcg gtatctaaag caagcaagtt
    27541 cttgttatca ttaaatataa actcgggtaa atgcaggata catttttcgt tattcaagca
    27601 actatcaatg aattgttttt taaaaaacag aaagctccat gacataagac tactctgccc
    27661 ctgaatttgg ttgtcagatt gtagatcaac accaaataac gtctttacat cttccctgag
    27721 attatagaat gccgtatcaa caagagcctc gatcgttttt ttatcaacca ttttaatgaa
    27781 ttcgttgtaa acttcctttt gcatcttata actgaccagc gcccatgaat aatcatgttg
    27841 ttttaaaacc agtatagctc ttaacagaca atatccatcg ccatctacag gagcatattt
    27901 taatcctaat gcctggttag tttcacgctg aataaaagat ataccagaca aatcaatgtc
    27961 agaatccaaa tcagatattc ccggcgtatt tatccgctct ggctggacac ttatattttc
    28021 atcatcaaaa caatactcag aaaaaacatc atcacacgca ttaatgtttt caatatactc
    28081 cataaagtta t
//
LOCUS       DAPOAV010000056        28000 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.056, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000056 DAPOAV010000000
VERSION     DAPOAV010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 28000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28000
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.056"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(60..650)
                     /gene="paaY"
                     /locus_tag="RN951_002756"
     CDS             complement(60..650)
                     /gene="paaY"
                     /locus_tag="RN951_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation protein PaaY"
                     /protein_id="HDX2527732.1"
                     /translation="MPIYQIDGLTPVVPEESFVHPTAVLIGDVILGKGVYVGPNASLR
                     GDFGRIVVKDGANIQDNCVMHGFPEQDTVVGEDGHIGHSAILHGCIIRRNALVGMNAV
                     VMDGAVIGENSIVGASAFVKAKAEMPANYLIVGSPAKAIRELSEQELAWKKQGTHEYQ
                     VLVTRCKQTLHQVEPLREIEPGRKRLVFDENLRPKQ"
     gene            complement(632..1582)
                     /gene="paaX"
                     /locus_tag="RN951_002757"
     CDS             complement(632..1582)
                     /gene="paaX"
                     /locus_tag="RN951_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation operon negative
                     regulatory protein PaaX"
                     /protein_id="HDX2527733.1"
                     /translation="MSKLDTFIQHAVNAVPVSGTSLISSLYGDSLSHRGGEIWLGSLA
                     ALLEGLGFGERFVRTALFRLNKEGWLDVSRIGRRSFYSLSDKGLRLTRRAESKIYRAE
                     QPAWDGKWLLLLSEGLDKSTLADVKKQLIWQGFGALAPSLMASPSQKLADVQTLLHEA
                     GVADNVICFEAQIPLALSRAALRARVEECWHLTEQNAMYETFIQSFRPLVPLLKEAAD
                     ELTPERAFHIQLLLIHFYRRVVLKDPLLPEELLPAHWAGHTARQLCINIYQRVAPAAL
                     AFVSEKGETSVGELPAPGSLYFQRFGGLNIEQEALCQFIR"
     gene            complement(1683..2996)
                     /gene="paaF"
                     /locus_tag="RN951_002758"
     CDS             complement(1683..2996)
                     /gene="paaF"
                     /locus_tag="RN951_002758"
                     /EC_number="6.2.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate--CoA ligase"
                     /protein_id="HDX2527734.1"
                     /translation="MITNTKLDPIETASVDELQALQTQRLKWTLKHAYENVPMYRRKF
                     DAAGVHPDDFRELSDLRKFPCTTKQDLRDNYPFDTFAVPMEQVVRIHASSGTTGKPTV
                     VGYTQNDIDNWANIVARSLRAAGGSPKDKIHVAYGYGLFTGGLGAHYGAERLGATVIP
                     MSGGQTEKQAQLIRDFQPDMIMVTPSYCLNLIEELERQLGGDASGCSLRVGVFGAEPW
                     TQAMRKEIERRLGITALDIYGLSEVMGPGVAMECLETTDGPTIWEDHFYPEIVNPHDG
                     TPLADGEHGELLFTTLTKEALPVIRYRTRDLTRLLPGTARTMRRMDRISGRSDDMLII
                     RGVNVFPSQLEEEIVKFEHLSPHYQLEVNRRGHLDSLSVKVELKESSLTLTHEQRCQV
                     CHQLRHRIKSMVGISTDVMIVNCGSIPRSEGKACRVFDLRNIVGA"
     gene            complement(3023..4228)
                     /gene="paaJ"
                     /locus_tag="RN951_002759"
                     /gene_synonym="paaE"
                     /gene_synonym="ydbW"
     CDS             complement(3023..4228)
                     /gene="paaJ"
                     /locus_tag="RN951_002759"
                     /gene_synonym="paaE"
                     /gene_synonym="ydbW"
                     /EC_number="2.3.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase"
                     /protein_id="HDX2527735.1"
                     /translation="MREAFICDGIRTPIGRYGGALSSVRADDLAAIPLRELLVRNPRL
                     DAECIDDVILGCANQAGEDNRNVARMATLLAGLPQSVSGTTINRLCGSGLDALGFAAR
                     AIKAGDGDLLIAGGVESMSRAPFVMGKAASAFSRQAEMFDTTIGWRFVNPLMAQQFGT
                     DSMPETAENVAELLKISREDQDSFALRSQQRTAKAQSSGILAEEIVPVVLKNKKGVVT
                     EIQHDEHLRPETTLEQLRGLKAPFRANGVITAGNASGVNDGAAALIIASEQMAAAQGL
                     TPRARIVAMATAGVEPRLMGLGPVPATRRVLERAGLSIHDMDVIELNEAFAAQALGVL
                     RELGLPDDAPHVNPNGGAIALGHPLGMSGARLALAASHELHRRNGRYALCTMCIGVGQ
                     GIAMILERV"
     gene            complement(4228..4650)
                     /gene="paaI"
                     /locus_tag="RN951_002760"
     CDS             complement(4228..4650)
                     /gene="paaI"
                     /locus_tag="RN951_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyphenylacetyl-CoA thioesterase PaaI"
                     /protein_id="HDX2527736.1"
                     /translation="MSHKAWQNAHAMYENDACAKALGIDIISMDEGFAVVTMTVTAQM
                     LNGHQSCHGGQLFSLADTAFAYACNSQGLAAVASACTIDFLRPGFAGDTLTATAQVRH
                     QGKQTGVYDIEIVNQQQKTVALFRGKSHRIGGTITGEA"
     gene            complement(4640..6067)
                     /gene="paaC"
                     /locus_tag="RN951_002761"
     CDS             complement(4640..6067)
                     /gene="paaC"
                     /locus_tag="RN951_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-CoA dehydrogenase PaaC"
                     /protein_id="HDX2527737.1"
                     /translation="MMINVQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRA
                     IDGIHARLNSRVTRGKLTAETCERTLKRLIPVTDIHALAAADLVIEAASERLEVKKAL
                     FAQLAEVCPPQTLLTTNTSSISITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLA
                     TAAEVVEQLCELTLSWGKQPVRCHSTPGFIVNRVARPYYSEAWRALEEQVAAPEVIDA
                     ALRDGAGFPMGPLELTDLIGQDVNFAVTCSVFNAFWQERRFLPSLVQQELVIGGRLGK
                     KSGLGVYDWRAEREAVVGLEAVSDSFSPMKVEKKSDGVTEIDDVLLIETQGETAQALA
                     IRLARPVVVIDKMAGKVVTIAAAAVNPDSATRKAIYYLQQQGKTVLQIADYPGMLIWR
                     TVAMIINEALDALQKGVASEQDIDTAMRLGVNYPYGPLAWGAQLGWQRILRLLENLQH
                     HYGEERYRPCSLLRQRALLESGYES"
     gene            complement(6069..6857)
                     /gene="paaB"
                     /locus_tag="RN951_002762"
     CDS             complement(6069..6857)
                     /gene="paaB"
                     /locus_tag="RN951_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA
                     isomerase"
                     /protein_id="HDX2527738.1"
                     /translation="MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVER
                     DDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDLGMSVERFYNPLVRRLAKLPKPV
                     ICAVNGVAAGAGATLALGGDIVIAARSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARA
                     MGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINS
                     AETNTLDTQLDLERDYQRLAGRSADYREGVSAFLAKRSPQFTGK"
     gene            complement(6857..7624)
                     /locus_tag="RN951_002763"
     CDS             complement(6857..7624)
                     /locus_tag="RN951_002763"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dehydroadipyl-CoA hydratase"
                     /protein_id="HDX2527739.1"
                     /translation="MSELIVSRQQRVLLLTLNRPAARNALNNALLMQLVNELEAAATD
                     TSISVCVITGNARFFAAGADLNEMAEKDLAATLNDTRPQLWARLQAFNKPLIAAVNGY
                     ALGAGCELALLCDVVVAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASKMVLSG
                     ESITAQQAQQAGLVSDVFPSDLTLEYALQLASKMARHSPLALQAAKQALRQSQEVALQ
                     AGLAQERQLFTLLAATEDRHEGISAFLQKRTPDFKGR"
     gene            complement(7621..8691)
                     /gene="paaK"
                     /locus_tag="RN951_002764"
     CDS             complement(7621..8691)
                     /gene="paaK"
                     /locus_tag="RN951_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate-CoA oxygenase/reductase subunit
                     PaaK"
                     /protein_id="HDX2527740.1"
                     /translation="MTTFHSLTVAKVESETRDAVTITFAVPQPLQEAYRFRPGQHLTL
                     KASFDGEELRRCYSICRSYLPGEISVAVKAIEGGRFSRYAREHIRQGMTLEVMVPQGH
                     FGYQPQAERQGRYLAIAAGSGITPMLAIIATTLQTEPESQFTLIYGNRTSQSMMFRQA
                     LADLKDKYPQRLQLLCIFSQETLDSDLLHGRIDGEKLQSLGASLINFRLYDEAFICGP
                     AAMMDDAETALKALGMPDKTIHLERFNTPGTRVKRSVNVQSDGQKVTVRQDGRDREIV
                     LNADDESILDAALRQGADLPYACKGGVCATCKCKVLRGKVAMETNYSLEPDELAAGYV
                     LSCQALPLTSDVVVDFDAKGMA"
     gene            complement(8699..9196)
                     /gene="paaD"
                     /locus_tag="RN951_002765"
     CDS             complement(8699..9196)
                     /gene="paaD"
                     /locus_tag="RN951_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415909.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate degradation protein PaaD"
                     /protein_id="HDX2527741.1"
                     /translation="MQRLATIAPPQVHEIWALLSQIPDPEIPVLTITDLGMVRNVTQM
                     GEGWVIGFTPTYSGCPATEHLIGAIREAMTTNGFTPVQVVLQLDPAWTTDWMTPDARE
                     RLREYGISPPAGHSCHAHLPPEVRCPRCASVHTTLISEFGSTACKALYRCDSCREPFD
                     YFKCI"
     gene            complement(9211..9957)
                     /gene="paaC"
                     /locus_tag="RN951_002766"
     CDS             complement(9211..9957)
                     /gene="paaC"
                     /locus_tag="RN951_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate-CoA oxygenase subunit PaaC"
                     /protein_id="HDX2527742.1"
                     /translation="MNQLTAYTLRLGDNCLVLSQRLGEWCGHAPELEIDLALANIGLD
                     LLGQARNFLSYAAELAGEGDEDTLAFTRDERQFSNLLLVEQPNGNFADTIARQYFIDA
                     WHVALFTRLMESRDPQLAAISAKAIKEARYHLRFSRGWLERLGNGTDVSGQKMQQAIN
                     KLWRFTAELFDADEIDIALSEEGIAVDPRTLRAAWEAEVFAGINEATLNVPQEQAYRT
                     GGKKGLHTEHLGPMLAEMQYLQRVLPGQQW"
     gene            complement(9966..10253)
                     /gene="paaB"
                     /locus_tag="RN951_002767"
     CDS             complement(9966..10253)
                     /gene="paaB"
                     /locus_tag="RN951_002767"
                     /EC_number="1.14.13.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,2-phenylacetyl-CoA epoxidase subunit B"
                     /protein_id="HDX2527743.1"
                     /translation="MSNVYWPLYEVFVRGKQGLSHRHVGSLHAADERMALENARDAYT
                     RRSEGCSIWVVKASEIVASQPEERGEFFDPAESKVYRHPTFYTIPDGIEHM"
     gene            complement(10265..11194)
                     /gene="paaA"
                     /locus_tag="RN951_002768"
     CDS             complement(10265..11194)
                     /gene="paaA"
                     /locus_tag="RN951_002768"
                     /EC_number="1.14.13.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,2-phenylacetyl-CoA epoxidase subunit A"
                     /protein_id="HDX2527744.1"
                     /translation="MTQEERFEQRIAQETAIEPQDWMPDAYRKTLIRQIGQHAHSEIV
                     GMLPEGNWITRAPTLRRKAILLAKVQDEAGHGLYLYSAAETLGCAREDIYQKMLDGRM
                     KYSSIFNYPTLSWADIGVIGWLVDGAAIVNQVALCRTSYGPYARAMVKICKEESFHQR
                     QGFEACMALAQGSEAQKQMLQDAINRFWWPALMMFGPNDDNSPNSARSLTWKIKRFTN
                     DELRQRFVDNTVPQVEMLGMTVPDPDLHFDTESGHYRFGEIDWQEFNEVINGRGICNQ
                     ERLDAKRKAWEEGTWVREAALAHAQKQHARKVA"
     gene            11479..13524
                     /gene="paaZ"
                     /locus_tag="RN951_002769"
     CDS             11479..13524
                     /gene="paaZ"
                     /locus_tag="RN951_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation bifunctional
                     protein PaaZ"
                     /protein_id="HDX2527745.1"
                     /translation="MQQLASFLSGTWQSGRGRSRLIHHAISGEALWEVTSEGLDMAAA
                     RQFAIEKGAPALRAMTFIERAAMLKAVAKHLLSEKERFYALSAQTGATRADSWVDIEG
                     GIGTLFTYASLGSRELPDDTLWPEDELIPLSKEGGFAARHLLTSKSGVAVHINAFNFP
                     CWGMLEKLAPTWLGGMPAIIKPATATAQLTQAMVKSIVDSGLVPEGAISLICGSAGDL
                     LDHLDSQDVVTFTGSAATGQMLRVQPNIVAKSIPFTMEADSLNCCVLGEDVTPDQPEF
                     ALFIREVVREMTTKAGQKCTAIRRIIVPQALVNAVSDALVARLQKVVVGDPAQEGVKM
                     GALVNAEQRADVQEKVNILLAAGCEIRLGGQADLSAAGAFFPPTLLYCPQPDETPAVH
                     ATEAFGPVATLMPAQNQRHALQLACAGGGSLAGTLVTADPQIARQFIADAARTHGRIQ
                     ILNEESAKESTGHGSPLPQLVHGGPGRAGGGEELGGLRAVKHYMQRTAVQGSPTMLAA
                     ISKQWVRGAKVEEDRIHPFRKYFEELQPGDSLLTPRRTMTEADIVNFACLSGDRFYAH
                     MDKIAAAESIFGERVVHGYFVLSAAAGLFVDAGVGPVIANYGLESLRFIEPVKPGDTI
                     QVRLTCKRKTLKKQRSAEEKPTGVVEWAVEVFNQHQTPVALYSILTLVARQHGDFVD"
     gene            13772..16045
                     /gene="tynA"
                     /locus_tag="RN951_002770"
     CDS             13772..16045
                     /gene="tynA"
                     /locus_tag="RN951_002770"
                     /EC_number="1.4.3.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415904.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primary-amine oxidase"
                     /protein_id="HDX2527746.1"
                     /translation="MGSPSLYSARKTTLALAVALSFAWQAPVFAHGGEAHMVPMDKTL
                     KEFGADVQWDDYAQLFTLIKDGAYVKVKPGAQTAIVNGQPLALQVPVVMKDNKAWVSD
                     TFINDVFQSGLDQTFQVEKRPHPLNALTADEIKQAVEIVKASADFKPNTRFTEISLLP
                     PDKEAVWAFALENKPVDQPRKADVIMLDGKHIIEAVVDLQNNKLLSWQPIKDAHGMVL
                     LDDFASVQNIINNSEEFAAAVKKRGITDAKKVITTPLTVGYFDGKDGLKQDARLLKVI
                     SYLDVGDGNYWAHPIENLVAVVDLEQKKIVKIEEGPVVPVPMTARPFDGRDRVAPAVK
                     PMQIIEPEGKNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSL
                     GGMIVPYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVP
                     MEIPRAIAVFERYAGPEYKHQEMGQPNVSTERRELVVRWISTVGNYDYIFDWIFHENG
                     TIGIDAGATGIEAVKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDV
                     DGENNSLVAMDPVVKPNTAGGPRTSTMQVNQYNIGNEQDAAQKFDPGTIRLLSNPNKE
                     NRMGNPVSYQIIPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEG
                     KYPNRSTHDTGLGQYSKDNESLDNTDAVVWMTTGTTHVARAEEWPIMPTEWVHTLLKP
                     WNFFDETPTLGALKKDK"
     gene            complement(16103..17602)
                     /gene="feaB"
                     /locus_tag="RN951_002771"
                     /gene_synonym="maoB"
                     /gene_synonym="padA"
     CDS             complement(16103..17602)
                     /gene="feaB"
                     /locus_tag="RN951_002771"
                     /gene_synonym="maoB"
                     /gene_synonym="padA"
                     /EC_number="1.2.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415903.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetaldehyde dehydrogenase"
                     /protein_id="HDX2527747.1"
                     /translation="MTEPHVAVLSQVQQFLDRQHGLYIDGRPGPAQSEKRLAIFDPAT
                     GQEIASTADANEADVDNAVMSAWRAFVSRRWAGRLPAERERILLRFADLVEQHSEELA
                     QLETLEQGKSIAISRAFEVGCTLNWMRYTAGLTTKIVGKTLDLSIPLPQGARYQAWTR
                     KEPVGVVAGIVPWNFPLMIGMWKVMPALAAGCSIVIKPSETTPLTMLRVAELASEAGI
                     PDGVFNVVTGSGAVCGAALTSHPHVAKISFTGSTATGKGIARTAADHLTRVTLELGGK
                     NPAIVLKDADPQWVIEGLMTGSFLNQGQVCAASSRIYIEAPLFDTLVSGFEQAVKSLQ
                     VGPGMSPVAQINPLVSRAHCDKVCSFLDDAQAQQAELIRGSNGPAGEGYYVAPTLVVN
                     PDAKLRLTREEVFGPVVNLVRVADGEEALQLANDTEYGLTASVWTQNLSQALEYSDRL
                     QAGTVWVNSHTLIDANLPFGGMKQSGTGRDFGPDWLDGWCETKSVCVRY"
     gene            17838..18743
                     /gene="feaR"
                     /locus_tag="RN951_002772"
     CDS             17838..18743
                     /gene="feaR"
                     /locus_tag="RN951_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator FeaR"
                     /protein_id="HDX2527748.1"
                     /translation="MNPAVDNEFQQWLSQINQVCGNFTGRLLTERYTGVLDTHFAKGL
                     KLSTVTTSGVNLSRTWQEVKGSDDAWFYTVFQLSGQAIMEQDERQVQIGAGDITLLDA
                     SRPCSLYWQESSKQISLLLPRTLLEQYFPHQKPVCAERLDADLPMVQLSHRLLQESMN
                     NPALSETESEAALQAMVCLLRPVLHQRESVQPRRERQFQKVVTLIDDNIREEILRPEW
                     IAGETGMSVRSLYRMFADKGLVVAQYIRNRRLDFCADAIRHAADDEKLAGIGFHWGFS
                     DQSHFSTVFKQRFGMTPGEYRRKFR"
     gene            complement(18915..19241)
                     /locus_tag="RN951_002773"
     CDS             complement(18915..19241)
                     /locus_tag="RN951_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbL family protein"
                     /protein_id="HDX2527749.1"
                     /translation="MKKTLLLCAFLVGLVSSNVMALTLDEARTQGRVGETFYGYLVAL
                     KTDAETEKLVADINAERKASYQQLAKQNNVSVDDIAKLAGQKLVARAKPGEYVQGING
                     KWVRKF"
     gene            complement(19249..19434)
                     /locus_tag="RN951_002774"
     CDS             complement(19249..19434)
                     /locus_tag="RN951_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnbE family lipoprotein"
                     /protein_id="HDX2527750.1"
                     /translation="MKILLAALTSSFMLVGCTPRIEVAAPKEPITINMNVKIEHEIII
                     KADKDVEELLETRSDLF"
     gene            complement(19431..22070)
                     /locus_tag="RN951_002775"
     CDS             complement(19431..22070)
                     /locus_tag="RN951_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbH family protein"
                     /protein_id="HDX2527751.1"
                     /translation="MLGKYKAVLALLLLIILVPLTLLMTLGLWVPTLAGIWLPLGTRI
                     ALDESPRITRKGLIIPDLRYLVGDCQLAHITNASLSHPSRWLLNVGTVELDSACLAKL
                     PQTEQSPAAPKTLAQWQAMLPNTWINIDKLIFSPWQEWQGKLSLALTSDIQQLRYQGE
                     KVKFQGQLKGQQLTVSELDVVAFENQPPVKLVGEFAMPLVPDGLPVSGHATATLNLPQ
                     EPSLVDAELDWQENSGQLIVLARDNGDPLLDLPWQITRQQLTVSDGRWSWPYAGFPLS
                     GRLGVKVDNWQAGLENALVSGRLSVLTQGQAGKGNAVLNFGPGKLSMDNSQLPLQLTG
                     EAKQADLILYARLPAQLSGSLSDPTLTFEPGALLRSKGRVIDSLDIDEIRWPLAGVKV
                     TQRGVDGRLQAILQAHENELGDFVLHMDGLANDFLPDAGRWQWRYWGKGSFTPMNATW
                     DVAGKGEWHDSTITLTDLSTGFDQLQYGTMTVEKPRLILDKPIVWVRDAQHPSFSGAL
                     SLDAGQTLFTGGSVLPPSTLKFSVDGRDPTYFLFKGDLHAGEIGPVRVNGRWDGIRLR
                     GNAWWPKQSLTVFQPLVPPDWKMNLRDGELYAQVAFSAAPEQGFRAGGHGVLKGGSAW
                     MPDNQVNGVDFVLPFRFADGAWHLGTRGPVTLRIAEVINLVTAKNITADLQGRYPWTE
                     EEPLLLTDVSVDVLGGNVLMKQLRMPQHDPALLRLNNLSSSELVSAVNPKQFAMSGAF
                     SGALPLWLNNEKWIVKDGWLANSGPMTLRLDKDTADAVVKDNMTAGSAINWLRYMEIS
                     RSSTKINLDNLGLLTMQANITGTSRVDGKSGTVNLNYHHEENIFTLWRSLRFGDNLQA
                     WLEQNARLPGNDCPQGKECEEKQ"
     gene            22278..23267
                     /gene="ldhA"
                     /locus_tag="RN951_002776"
     CDS             22278..23267
                     /gene="ldhA"
                     /locus_tag="RN951_002776"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HDX2527752.1"
                     /translation="MKLAVYSTKQYDKKYLQQVNESFGFELEFFDFLLTEKTAKTANG
                     CEAVCIFVNDDGSRPVLEELKKHGVKYIALRCAGFNNVDLDAAKELGLKVVRVPAYDP
                     EAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGLTGFTMYGKTAGVIGTGKIGVAML
                     RILKGFGMRLLAFDPYPSAAALELGVEYVDLPTLFSESDVISLHCPLTPENYHLLNEA
                     AFEQMKNGVMIVNTSRGALIDSQAAIEALKNQKIGSLGMDVYENERDLFFEDKSNDVI
                     QDDVFRRLSACHNVLFTGHQAFLTAEALTSISQTTLQNLSNLEKGETCPNELV"
     gene            23378..23800
                     /gene="hslJ"
                     /locus_tag="RN951_002777"
     CDS             23378..23800
                     /gene="hslJ"
                     /locus_tag="RN951_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HslJ"
                     /protein_id="HDX2527753.1"
                     /translation="MKKVAAFVALSLLMAGCVSNDKIAVTPEQLQHHRFVLESVNGKP
                     VTSDKNPPEISFGEKMMISGSMCNRFSGEGKLSNGELTAKGLAMTRMMCANPQLNELD
                     NTISEMLKEGAQVDLTANQLTLATAKQTLTYKLADLMN"
     gene            complement(23797..24063)
                     /locus_tag="RN951_002778"
     CDS             complement(23797..24063)
                     /locus_tag="RN951_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015964583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing protein"
                     /protein_id="HDX2527754.1"
                     /translation="MRAAFWVGCAALLLSACSSEPVQQATAAHVAPGLKASMSSSGEA
                     NCAMIGGSLSVARQLDGTAIGMCALPNGKRCSEQSLAAGSCGSY"
     gene            24337..27861
                     /gene="nifJ"
                     /locus_tag="RN951_002779"
     CDS             24337..27861
                     /gene="nifJ"
                     /locus_tag="RN951_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HDX2527755.1"
                     /translation="MITIDGNGAVASVAFRTSEVIAIYPITPSSTMAEQADAWAGNGL
                     KNVWGDTPRVVEMQSEAGAIATVHGALQTGALSTSFTSSQGLLLMIPTLYKLAGELTP
                     FVLHVAARTVATHALSIFGDHSDVMAVRQTGCAMLCAANVQEAQDFALISQIATLKSR
                     VPFIHFFDGFRTSHEINKIVPLADDTILDLMPQVEIDAHRARALNPEHPVIRGTSANP
                     DTYFQSREATNPWYNAVYDHVEQAMNDFSAATGRQYQPFEYYGHPQAERVIILMGSAI
                     GTCEEVVDELLTRGEKVGVLKVRLYRPFSAKHLLQALPGSVRSVAVLDRTKEPGAQAE
                     PLYLDVMTALAEAFNNGERETLPRVIGGRYGLSSKEFGPDCVLAVFAELNAAKPKARF
                     TVGIYDDVTNLSLPLPENTLPNSAKLEALFYGLGSDGSVSATKNNIKIIGNSTPWYAQ
                     GYFVYDSKKAGGLTVSHLRVSEQPIRSAYLISQADFVGCHQLQFIDKYQMAERLKPGG
                     IFLLNTPYSADEVWSRLPQEVQAVLNQKKARFYVINAAKIARECGLAARINTVMQMAF
                     FHLTQILPGDSALAELQGAIAKSYSSKGQDLVERNWQALALARESVEEVPLQPVNPHS
                     ANRPPVVSDAAPDFVKTVTAAMLAGLGDALPVSALPPDGTWPMGTTRWEKRNIAEEIP
                     IWKEELCTQCNHCVAACPHSAIRAKVVPPEAMENAPASLHSLDVKSRDMRGQKYVLQV
                     APEDCTGCNLCVEVCPAKDRQNPEIKAINMMSRLEHVEEEKINYDFFLNLPEIDRSKL
                     ERIDIRTSQLITPLFEYSGACSGCGETPYIKLLTQLYGDRMLIANATGCSSIYGGNLP
                     STPYTTDANGRGPAWANSLFEDNAEFGLGFRLTVDQHRVRVLRLLDQFADKIPAELLT
                     ALKSDATPEVRREQVAALRQQLNDVAEAHELLRDADALVEKSIWLIGGDGWAYDIGFG
                     GLDHVLSLTENVNILVLDTQCYSNTGGQASKATPLGAVTKFGEHGKRKARKDLGVSMM
                     MYGHVYVAQISLGAQLNQTVKAIQEAEAYPGPSLIIAYSPCEEHGYDLALSHDQMRQL
                     TATGFWPLYRFDPRRADEGKLPLALDSRPPSEALEETLLHEQRFRRLNSQQPEVAEQL
                     WKDAAADLQKRYDFLAQMAGKAEKSNTD"
BASE COUNT         6811 a         7537 c         6895 g         6757 t
ORIGIN      
        1 agcagagctt aaacataact ctgctttata attaaaggga caaaataatt ttacatctgt
       61 tactgtttcg gtcgcagatt ctcatcaaat accaggcgtt tcctgccagg ttcaatttcc
      121 cgcaatggct cgacttgatg taacgtctgc ttacagcgtg tcaccagcac ctggtactca
      181 tgcgtaccct gctttttcca tgccaactcc tgctcactga gttcacgaat cgctttcgcc
      241 gggctgccga caatcaggta attagctggc atttctgctt tggctttcac aaatgcggat
      301 gcaccaacaa tgctgttctc gccaatcacc gcaccgtcca tcactaccgc gttcattccc
      361 actaatgcat tgcggcggat aatgcagccg tgaaggatag cgctatgacc aatatgtcca
      421 tcttctccta caacagtatc ctgctcggga aaaccgtgca taacgcaatt atcctgaatg
      481 ttcgcgccat ctttcaccac gatacgacca aaatcgccac gcaggctggc atttggccca
      541 acgtaaacgc ccttgccgag aataacatcg ccgatcaata ccgctgtcgg atggacaaaa
      601 ctctcttctg gcacaaccgg agtcagaccg tctatctgat aaattggcat aacgcctcct
      661 gttcaatatt caagccgcca aaacgttgaa aatacaggct tcccggcgca ggcagttcac
      721 cgaccgaggt ttcacctttt tcactaacga acgctaaagc agcaggcgct acgcgctgat
      781 aaatgttgat acacagctga cgcgccgtat gccctgccca gtgtgccgga agcaactcct
      841 ccggcaacaa tgggtcttta aggacgacac ggcgataaaa atggatcagt aaaagctgaa
      901 tatgaaatgc ccgctccggg gttaactcgt ctgccgcctc ttttaaaagc ggcaccagcg
      961 ggcggaatga ctgaataaag gtttcgtaca tggcattttg ttcagttaaa tgccagcact
     1021 cttctactct ggcacgcagt gctgcgcgag aaagcgccag tggtatttgc gcttcaaaac
     1081 aaatcacgtt atccgccaca cccgcttcat gcaaaagtgt ctgtacatcg gccagttttt
     1141 gcgacggcga tgccatcagg ctgggtgcca gtgcgccaaa accttgccag atcaactgct
     1201 ttttgacatc agccagcgtt gatttatcta aaccttccga gagcaacagg agccatttac
     1261 catcccatgc aggttgctct gcgcgataaa ttttactttc tgcccgtcgc gtcaggcgca
     1321 agcctttatc actgaggcta tagaaactgc gtcgcccgat gcgggaaaca tccagccagc
     1381 cttctttatt aagacgaaac aaagcggtgc gcacgaaacg ctcaccaaat cccagccctt
     1441 ccagcaaagc agccagacta cccaaccaga tttcaccacc acgatgggaa agcgaatcac
     1501 catacagaga ggagatcaaa gatgtgccac tgaccggaac agcgtttaca gcatgttgga
     1561 taaaagtatc aagtttactc attcgcttca gtctgttgtt attgttgtga tttatgaatc
     1621 atagcacagg tcgtatcgac ttctggccct ggcgctttac cccaccaggg ccagacgata
     1681 cgtcaggcac caacaatatt gcgcagatca aacacccgac acgccttgcc ttctgaacgc
     1741 gggatactgc cacagttaac gatcatcaca tcggtagaga tccccaccat cgacttaatc
     1801 cgatggcgca gctggtggca tacctggcaa cgctgctcat gcgtcaatgt caggctactt
     1861 tctttcaact ccactttcac agaaagtgaa tcaagatgcc cccggcggtt cacctccagt
     1921 tggtaatgcg gcgataaatg ttcgaatttg acaatctctt cttccagttg tgacggaaag
     1981 acatttacac cgcgaataat caacatgtca tcgctgcgtc cgctgatgcg atccatgcgg
     2041 cgcatagtcc gcgccgttcc tggtaacagt cgggttaaat cacgcgtgcg gtaacgaatg
     2101 accggcaatg cttctttggt cagcgtggtg aataacagtt cgccatgttc accatcggca
     2161 agcggtgtgc cgtcatgagg attaacaatt tcaggataga aatgatcttc ccaaatggtt
     2221 gggccgtcgg tagtttccag acactccatc gccacccccg gccccatcac ttctgacagg
     2281 ccataaatat ccagtgcggt gatccccagg cgacgctcaa tctctttacg catggcctgt
     2341 gtccacggct cagcaccaaa tactccaacc cgcagcgagc aaccgctggc atcaccgccc
     2401 aactgccgct ccagctcttc aatcaggtta aggcaataag atggcgtaac catgatcata
     2461 tctggttgaa aatcacggat cagttgcgct tgtttttccg tctgcccgcc agacatcggg
     2521 atcaccgtag cgcccagacg ttcggcacca tagtgcgcac ccagcccacc agtaaacagg
     2581 ccgtaaccat aggcaacatg aattttgtct ttgggcgagc cccctgccgc acgcaaagaa
     2641 cgcgctacaa tattggccca gttatcaata tcgttttgcg tatagccgac aactgtcggt
     2701 ttacctgtgg ttcccgaaga agcatgaatg cgcaccactt gttccattgg cacggcaaag
     2761 gtgtcaaagg gatagttgtc gcgcagatcc tgtttggtgg tacagggaaa tttacgcagg
     2821 tctgaaagtt ccctgaaatc atcaggatgt acgcctgctg cgtcgaattt gcgccgatac
     2881 atcggcacat tttcatacgc gtgtttgagc gtccatttca gacgctgtgt ttgcaacgcc
     2941 tgtaactcat caacagacgc ggtttcaatc gggtcaagct ttgtattggt tatcattgta
     3001 gggtactcgc aggttgatat gctcaaacac gctccagaat catggcgatg ccctgaccga
     3061 caccgatgca catggtgcac aatgcgtaac gaccgttacg ccgatgcagc tcatggctgg
     3121 cagccagtgc caggcgggca ccactcattc ccaacggatg gcctaaggcg atagcgcctc
     3181 cgttggggtt aacatgtggg gcatcatcag gcagccccaa ttcgcgtagt acacccaacg
     3241 cctgggccgc gaacgcttcg ttcagttcaa tcacgtccat atcgtgaata ctcagccctg
     3301 cgcgttccag cacccggcga gttgcaggca ccggaccaag ccccatcagg cgcggttcca
     3361 ccccggcggt tgccatggct acgatacgcg cccgcggtgt cagtccttgc gctgctgcca
     3421 tctgttcact ggcaataatc aacgcagcgg ctccgtcatt caccccggaa gcattgcctg
     3481 cggtaatcac cccattggca cgaaatggtg cttttaaccc acgtaactgt tccagcgtcg
     3541 tttccgggcg cagatgctca tcatgttgta tttctgttac aacacctttc ttgtttttca
     3601 acacaaccgg aacaatctcc tcagccagaa tgcctgagga ttgcgctttt gccgtacgtt
     3661 gctgactgcg tagcgcaaaa ctatcttgat cttctcgtga gatttttaac agttcagcta
     3721 cattctctgc cgtttccggc atgctgtcag ttccaaattg ctgagccatg agcgggttca
     3781 caaatcgcca gccaatagtg gtatcgaaca tctcagcctg acgagaaaat gcactggctg
     3841 ccttgcccat aacaaacggt gcccgtgaca ttgactccac gccaccggcg atcagcaaat
     3901 cgccatcgcc cgctttaatc gcccgtgcgg caaaccccag tgcgtccagc ccggaaccac
     3961 acaagcggtt aatggttgtg ccggaaacac tctgcggcag ccccgccagt aaagtcgcca
     4021 tccgggctac gttacggtta tcttctcccg cctgattagc acagccgagg atcacatcat
     4081 cgatacactc cgcatcgaga cgcgggtttc gcaccagcag ttcccgcaaa gggatagcag
     4141 ccagatcatc agcccgaaca cttgataatg ccccgccgta gcgaccaatt ggcgtacgaa
     4201 ttccgtcaca aataaaggct tcacgcatca ggcttctcct gtaatggtgc cgccgatgcg
     4261 gtgagattta ccgcgaaaca gcgcaaccgt tttttgttgt tggttaacaa tttcgatgtc
     4321 gtaaacaccg gtttgcttgc cctgatgacg tacctgcgca gtagcagtta aggtgtctcc
     4381 ggcaaagcct ggacgcaaaa aatcaatcgt gcaggcagaa gcgacggctg ccagcccctg
     4441 gctattgcag gcgtaggcaa aggcagtatc agccagtgaa aatagctgcc cgccgtggca
     4501 actttgatga ccgttaagca tttgtgcagt gacggtcatg gtcactacag caaagccttc
     4561 atccattgag ataatgtcga tgccaagcgc tttggcgcag gcatcgttct catacattgc
     4621 atgggcattt tgccaggcct tatgactcat aaccgctctc cagaagcgcc cgttggcgca
     4681 gcaatgaaca tgggcgatag cgttcttcgc catagtgatg ctgtagattt tcaaggagcc
     4741 ttaatattcg ctgccagcca agttgcgctc cccaggcaag tgggccatat ggataattca
     4801 ccccaagacg catggcggta tcgatatcct gttcagaggc cacgcctttt tgaagcgcat
     4861 caagggcttc attgatgatc attgctaccg ttcgccaaat cagcattcct gggtaatctg
     4921 caatttgcag cactgttttg ccctgctgtt gcaggtaata aatggccttg cgggtcgctg
     4981 agtccgggtt caccgctgca gcagcaatgg tcaccacctt gcccgccatt ttatcgatca
     5041 ctaccaccgg gcgtgccagt cgtattgcca gcgcctgtgc cgtctcgcct tgtgtctcaa
     5101 tcaataaaac atcgtcaatt tccgtgacac cgtcactttt cttttctact ttcattgggc
     5161 taaaactgtc gcttaccgct tccaggccaa caactgcctc acgttccgcg cgccagtcgt
     5221 acacgcccag cccacttttc ttgcccaacc gtccaccaat caccagttcc tgttgcacca
     5281 gcgaaggtaa aaaacgacgc tcctgccaga aagcgttaaa caccgaacag gtgacagcaa
     5341 aattgacgtc ctgaccaatc agatcggtta attccagcgg ccccatcggg aaaccagcgc
     5401 catcgcgaag tgcagcgtca atcacttctg gtgcagcaac ctgctcttcc agtgcccgcc
     5461 aggcctcgga ataataagga cgcgcaacac ggttaacgat aaatccagga gtcgaatgac
     5521 agcgcacagg ctgcttaccc caactcaacg ttagttcaca caactgctca acaacttccg
     5581 ccgccgttgc cagcccactg accacctcca ccaacttcat caccggtgcc gggttaaaaa
     5641 aatgcagccc cgcaacacgt tcaggatttt ttatctccgc agcaatcgcg gttatagaga
     5701 ttgacgaagt gttagtggtc aatagcgttt gtggcgggca aacttccgcc agctgtgcaa
     5761 agagcgcttt tttgacttcc agacgttcag acgccgcttc aatgaccagg tccgcagctg
     5821 ccagcgcgtg aatatcggtc accgggatca ggcgtttcaa tgtgcgttca caggtttcag
     5881 cagtcagttt tccccgcgtc acgcgtgaat ttagccgcgc gtgtatcccg tcgattgcgc
     5941 gggtcagcgc ttcagcagaa atgtcataca gtaaaacctg gtgtccatga ctggcagcaa
     6001 cttcagcaat gcctgccccc atggtgccgc tcccaatcac tgccacagtt tgcacattta
     6061 tcatcatgct atttccccgt gaactgcggt gagcgtttag ccaggaacgc actgacacct
     6121 tcacgataat ctgcgctccg tccggcaagt cgctgatagt cacgttccag atccagttgc
     6181 gtatcgagcg tattggtttc agcgctattt atcgcttgct tgataagtcc aagaccaaat
     6241 gtcggttgtg tcgccagatg ccgtgccagc tgttgcgcgg tatctgccag cgtttcatca
     6301 tcaacaacct gccagatcat cccccattcg tgcgcctgtt cagcactcag ttgattcccc
     6361 agcagtgcca gccccatggc gcgcgctcgt ccggcaacgc gtggcagtaa ccaggttcca
     6421 ccgcaatcgg gtattaagcc taacttacta aacgccatga cgaattttgc tgaacgggca
     6481 gcaataacga tgtcgccccc cagtgccagt gttgcgcctg cccctgccgc cacgccattg
     6541 actgcacaga tcaccggttt tggcagtttt gccaggcgac gtaccagtgg gttatagaaa
     6601 cgttcaactg acatccctaa atccggtgcg gggcctgtgg gatcaacgtt acgatcgtta
     6661 agatcctgac cagcacaaaa tccgcgcccg gcacctgtaa gtaacaggca acggatagtg
     6721 tcgtcgcgct cgacctgttt caggcactct gccagttgtg cgtgcatctc atcattaaaa
     6781 ctgttcaggc gttccgggcg gttgagcgtt agtgtcatca cgcccttttc tacatgactg
     6841 aggatgaatt ccatcattag cgtcctttaa agtcgggcgt gcgtttttgt aagaaagcgg
     6901 agatgccttc atgacgatct tctgttgccg ccagcaaggt gaataactgt cgctcctggg
     6961 caagtccggc ttgcaaagcc acttcctgcg actggcgcag cgcttgcttt gccgcttgta
     7021 aggccagcgg cgagtgacgt gccattttcg atgccagctg taaggcgtat tcgagggtta
     7081 aatcgctggg gaagacgtcg ctaaccagcc cggcctgctg tgcttgctga gcggtgatac
     7141 tttctccgct cagcaccatt ttgctggcta acgatttacc gacactacgg attaaacgtt
     7201 gcgttccgcc tgcgccaggc atgatgccga gagtgatttc cggcaaccca aaacgcgcgt
     7261 tctctccggc aaccaccaca tcgcacaaca atgccagttc gcaacccgcc ccaagcgcgt
     7321 aaccattgac ggctgcgata agtggtttat taaaggcctg caatcgcgcc catagctgcg
     7381 gacgtgtatc gtttaaggtg gccgcgagat ctttttctgc catttcgttg agatcggccc
     7441 cagcggcaaa aaagcgtgca ttaccggtaa tcacacagac cgaaatgctg gtatcggtag
     7501 ccgcagcttc cagttcattt accagttgca tcagcagggc attatttagc gcattacgtg
     7561 cggcgggacg gttaagggtc agcaacaata ctcgttgctg acggctgacg atcagttcgc
     7621 tcatgccatc cccttcgcgt caaagtcaac caccacatcg ctggtcagcg gcagtgcctg
     7681 gcaactcaac acataacctg cggccagttc atccggttcc agactgtaat tggtttccat
     7741 cgccactttg ccacgcagca ctttgcattt gcaggtcgca cagacgccgc ctttgcaggc
     7801 atagggcaga tccgccccct ggcgcaatgc cgcatcgaga atgctttcat cgtcggcatt
     7861 aagcacgatt tcccgatccc gcccatcctg acgtacagtc actttttgtc cgtcactttg
     7921 cacgttaacg ctacgtttga cgcgcgtgcc aggcgtatta aaccgctcca gatgaatggt
     7981 tttatctggc attcccagtg cttttaaggc ggtttccgcg tcatccatca tcgccgccgg
     8041 accacaaata aatgcctcat cataaagacg aaaattaatg agcgaggccc caagtgactg
     8101 taatttttca ccgtcaatac gcccgtgaag cagatcgctg tcgagggttt cctgactgaa
     8161 aatgcacaac aactgtaaac gctgaggata tttgtctttc aggtctgcca gtgcctggcg
     8221 aaacatcatg ctctggctgg tacggttacc gtagatcagg gtgaactgac tttcaggctc
     8281 ggtttgtaaa gtggtggcga taatcgccag cattggcgta atacctgatc ctgctgcaat
     8341 tgccagatag cgcccctggc gttcggcctg cggctgatag ccgaaatgcc cctgcggcac
     8401 catgacctcc agcgtcatac cctggcggat gtgttcgcgg gcatagcggg agaaacgtcc
     8461 gccttcaatg gctttcaccg ccacactaat ttcgccaggc agatagctgc ggcaaatgga
     8521 gtaacaacgg cgtaattctt caccatcaaa gctggctttt aaggtcaaat gttgaccggg
     8581 gcgaaagcga tacgcctcct gcaaaggctg gggcaccgca aaggtaatgg tcaccgcatc
     8641 acgggtttcc gactcgactt ttgccactgt taaggaatga aacgttgtca tggcatcctc
     8701 aaatacattt gaaataatcg aaaggttcgc ggcaactatc gcagcggtac aatgctttgc
     8761 aggccgtgga accaaattca ctgataagtg tggtatggac gctggcgcag cgcgggcaac
     8821 gtacttctgg cggcaaatgg gcatggcaac tgtgtccggc gggcgggcta atgccatact
     8881 ctcgcagacg ctcacgggca tcgggggtca tccagtcggt ggtccatgcc gggtcgagtt
     8941 gcagcacaac ctgaacgggg gtaaacccgt tggttgtcat tgcctcacgt atcgcgccaa
     9001 tcaaatgttc cgttgccgga caaccggaat atgtcggcgt aaagccgatc acccatcctt
     9061 ctcccatctg tgtcacatta cgcaccatgc ctaaatcagt aatggtcagc accgggatct
     9121 ccgggtccgg gatctggctg agtagcgccc atatctcatg aacctgtggc ggtgcaatgg
     9181 tggccagacg ttgcataccc atctcctctg ttaccattgc tgaccgggca agacacgctg
     9241 gagatactgc atttctgcca gcatgggtcc aaggtgttcg gtatgcagtc cttttttacc
     9301 gccagtgcga tacgcctgct cttgcggtac gttcaatgtg gcttcgttga tcccggcaaa
     9361 aacttcggct tcccacgctg cgcgtaaagt gcgtggatca accgcaatac cctcttcact
     9421 cagtgcaata tcaatctcgt cggcatcgaa cagttcggcg gtaaaacgcc acaacttgtt
     9481 gatggcctgc tgcatctttt gccctgatac gtcagtacca ttgcccagtc gctccagcca
     9541 gccacgacta aaacgcaggt gatagcgcgc ttctttaatt gctttggcag aaatcgccgc
     9601 cagttgcgga tcacggcttt ccatcagacg ggtaaagagc gccacatgcc atgcatcgat
     9661 gaaatactgg cgtgcaatgg tgtcggcaaa attgccgttt ggttgttcaa ccaacaataa
     9721 gttgctgaac tggcgctcgt ctcgggtgaa ggcaagggta tcttcatcgc cttctcccgc
     9781 taattcagcg gcatacgata agaagttgcg tgcctgacct aataaatcga ggccaatgtt
     9841 tgccagtgcg agatcgattt ccagttccgg tgcgtgaccg caccattcac ccaaccgctg
     9901 ggagagcacc aggcagttat cgcccaggcg caaggtgtaa gccgttaact gattcatttc
     9961 cgacctcaca tgtgctcaat gccatcaggg atggtgtaaa acgttggatg gcgatagacc
    10021 ttgctttcag ccggatcaaa aaattcaccg cgttcttccg gttgcgaggc aacaatttca
    10081 ctcgccttca ccacccaaat tgaacatcct tcgctacgac gggtgtaagc atcacgggca
    10141 ttttccagtg ccatccgctc atcggcagca tgtaaactgc caacatggcg gtgtgataag
    10201 ccctgtttgc cacgcacgaa aacttcgtat aacggccagt aaacattact cattttgaat
    10261 ctccttatgc gaccttacgg gcatgttgtt tttgtgcatg ggccagcgct gcttcccgta
    10321 cccaggtacc ttcttcccag gctttacgtt tggcgtcgag cctctcctga ttacaaattc
    10381 cgcgaccgtt aattacttcg ttaaactcct gccagtcgat ctcaccaaag cggtagtgac
    10441 cgctttcagt gtcaaaatgc agatccgggt caggaacggt cataccgagc atttcaacct
    10501 gtggaacggt gttatccacg aaacgctggc ggagttcgtc gttggtgaaa cgtttgattt
    10561 tccaggtgag acttctggcg ctgtttggcg agttatcatc gtttggcccg aacatcatta
    10621 aggctggcca ccagaaacgg ttaatggcgt cttgcaacat ctgcttttga gcttcgctgc
    10681 cctgcgccag tgccatgcag gcttcaaacc cctgacgctg gtgaaaactc tcttctttgc
    10741 agattttcac cattgctctg gcatacgggc cataagaagt gcggcataac gccacctgat
    10801 tgacgatcgc tgcgccatcc accagccagc cgataacacc gatatcagcc caactcaatg
    10861 tcggataatt aaagatggag gaatatttca tccgtccgtc gagcattttt tggtagatgt
    10921 cttctctggc gcagcccagt gtttcggcgg cgctatagag atacagacca tgaccggctt
    10981 catcctgcac tttggccaac agaatggctt tacgccgcaa ggttggtgcg cgagtgatcc
    11041 agttaccttc aggcaacata ccaacaatct cggagtgcgc atgctgccca atctggcgga
    11101 tcaatgtctt tcggtaagca tcgggcatcc agtcctgtgg ctcgatagcc gtttcctggg
    11161 ctatccgttg ctcaaagcgt tcttcttggg tcacgtcatc acctttacga ttccagtttt
    11221 cgtgaattaa ttaaaaacac gaatcacatt gttttatgaa agttacacaa tagttaagta
    11281 aaatcacaaa ttttgtatgt ttgaactgtg acggatttcg caccctattt ttataaatca
    11341 ttatttatca gtgcattaat gttttccgca gttgctatac agatcgcata gttaacattt
    11401 cgttaaaaga tcccttgctt tttatgattc gcgatttaac tattagcaac agaaatgtga
    11461 aacatctgga gagtagcgat gcagcagtta gccagtttct tatccggtac ctggcagtct
    11521 ggccggggcc gtagccgttt gattcaccac gctattagcg gcgaggcgtt atgggaagtg
    11581 accagtgaag gtcttgatat ggcggctgcc cgccagtttg ccattgaaaa aggtgccccc
    11641 gcccttcgcg ctatgacctt tatcgaacgt gcggcgatgc ttaaagcggt cgctaaacat
    11701 ctgctgagtg aaaaagagcg tttctatgct ctttctgcgc aaacaggcgc aacgcgggca
    11761 gacagttggg ttgatattga aggtggcatt gggacgttat ttacttacgc cagcctcggt
    11821 agccgggagc tgcctgacga tacgctgtgg ccggaagatg aattgatccc cttatcgaaa
    11881 gaaggtggat ttgccgcgcg ccatttactg acctcaaagt caggcgtggc agtgcatatt
    11941 aacgccttta acttcccctg ctggggaatg ctggaaaagc tggcaccaac gtggctgggc
    12001 ggaatgccag ccatcatcaa accagctacc gcgacggccc aactgactca ggcgatggtg
    12061 aaatcaattg tcgatagtgg tcttgttccc gaaggcgcaa ttagtctgat ctgcggtagt
    12121 gctggcgact tgttggatca tctggacagc caggatgtgg tgactttcac ggggtcagcg
    12181 gcgaccggac agatgctgcg agttcagcca aatatcgtcg ccaaatctat ccccttcact
    12241 atggaagctg attccctgaa ctgctgcgta ctgggcgaag atgtcacccc ggatcaaccg
    12301 gagtttgcgc tgtttattcg tgaagttgtg cgtgagatga ccacaaaagc cgggcaaaaa
    12361 tgtacggcaa tccggcggat tattgtgccg caggcattgg ttaatgctgt cagtgatgct
    12421 ctggttgcgc gattacagaa agtcgtggtc ggtgatcctg ctcaggaagg cgtgaaaatg
    12481 ggcgcactgg taaatgctga gcagcgtgcc gatgtgcagg aaaaagtgaa catattgctg
    12541 gctgcaggat gcgagattcg cctcggtggt caggcggatt tatctgctgc gggtgccttc
    12601 ttcccgccaa ccttattgta ctgtccgcag ccggatgaaa caccggcggt acatgcaaca
    12661 gaagcctttg gccctgtcgc aacgctgatg ccagcacaaa accagcgaca tgctctgcaa
    12721 ctggcttgtg caggcggcgg tagccttgcg ggaacgctgg tgacggctga tccgcaaatt
    12781 gcgcgtcagt ttattgccga cgcggcacgt acgcatgggc gaattcagat cctcaatgaa
    12841 gagtcggcaa aagaatccac cgggcatggc tccccactgc cacaactggt acatggtggg
    12901 cctggtcgcg caggaggcgg tgaagaatta ggcggtttac gagcggtgaa acattacatg
    12961 cagcgaaccg ctgttcaggg tagtccgacg atgcttgccg ctatcagtaa acagtgggtg
    13021 cgcggtgcga aagtcgaaga agatcgtatt catccgttcc gcaaatattt tgaggagcta
    13081 caaccaggcg acagcctgtt gactccccgc cgcacaatga cagaggccga tattgttaac
    13141 tttgcttgcc tcagcggcga tcgtttctat gcacatatgg ataagattgc tgctgccgaa
    13201 tctattttcg gtgagcgggt ggtgcatggg tattttgtgc tttctgcggc tgcgggtctg
    13261 tttgtcgatg ccggtgtcgg tccggtcatt gctaactacg ggctggaaag cttgcgtttt
    13321 atcgaacccg taaagccagg cgataccatc caggtgcgtc tcacctgtaa gcgcaagacg
    13381 ctgaaaaaac agcgtagcgc agaagaaaaa ccaacaggtg tggtggaatg ggctgtagag
    13441 gtattcaatc agcatcaaac cccggtggcg ctgtattcaa ttctgacgct ggtggccagg
    13501 cagcacggtg attttgtcga ttaatcggtg aatgaagggc aacggcgaat agttgccctt
    13561 ttatttcact aagttttgtg acgttgtcac attatgcatg atgtgtacat ctattttcag
    13621 ggcatccact gtatgaaaag ctggcacacc tgccaaacaa cctggcaggt gcaggcaatc
    13681 ccctttgcat cagtactgat aatgtgaacc tgactaaacc gcccacagag cgcggttgct
    13741 aacaagaaca caacatctga cgaggttaat aatgggaagc ccctctctgt attctgcccg
    13801 taaaacaacc ctggcgttgg cagtcgcctt aagtttcgcc tggcaagcgc cggtatttgc
    13861 ccacggtggt gaagcgcata tggtgccaat ggataaaacg cttaaagaat ttggtgccga
    13921 tgtgcagtgg gacgactacg cccagctctt taccctgatt aaagatggcg cgtacgtgaa
    13981 agtgaagcct ggtgcgcaaa cagcaattgt taatggtcag cctctggcac tgcaagtacc
    14041 ggtagtgatg aaagacaata aagcctgggt ttctgacacc tttattaacg atgttttcca
    14101 gtccgggctg gatcaaacct ttcaggtaga aaagcgccct cacccactta atgcgctaac
    14161 tgcggacgaa attaaacagg ccgttgaaat tgttaaagct tccgcggact tcaaacccaa
    14221 tacccgtttt actgagatct ccctgctacc gccagataaa gaagctgtct gggcgtttgc
    14281 gctggaaaac aaaccggttg accagccgcg caaagccgac gtcattatgc tcgacggcaa
    14341 acatatcatc gaagcggtgg tggatctgca aaacaacaaa ctgctctcct ggcaacccat
    14401 taaagacgcc cacggtatgg tgttgctgga tgatttcgcc agtgtgcaga acattattaa
    14461 caacagtgaa gaatttgccg ctgccgtgaa gaaacgcggt attactgatg cgaaaaaagt
    14521 gattaccacg ccgctgaccg taggttattt cgatggtaaa gatggcctga aacaagatgc
    14581 ccggttgctc aaagtcatca gctatcttga tgtcggtgat ggcaactact gggcacatcc
    14641 catcgaaaac ctggtggcgg tcgttgattt agaacagaaa aaaatcgtta agattgaaga
    14701 aggtccggta gttccggtgc caatgaccgc acgcccattt gatggccgtg accgcgttgc
    14761 tccggcagtt aagcctatgc aaatcattga gcctgaaggt aaaaattaca ccattactgg
    14821 cgatatgatt cactggcgga actgggattt tcacctcagc atgaactctc gcgtcgggcc
    14881 gatgatctcc accgtgactt ataacgacaa tggcaccaaa cgcaaagtca tgtacgaagg
    14941 ttctctcggc ggcatgattg tgccttacgg tgatcctgat attggctggt actttaaagc
    15001 gtatctggac tctggtgact acggtatggg cacgctaacc tcaccaattg ctcgtggtaa
    15061 agatgccccg tctaacgcag tgctccttaa tgaaaccatc gccgactaca ctggcgtgcc
    15121 gatggagatc cctcgcgcta tcgcggtatt tgaacgttat gccgggccgg agtataagca
    15181 tcaggaaatg ggccagccca acgtcagtac cgaacgccgg gagttagtgg tgcgctggat
    15241 cagtacagtg ggtaactatg actacatttt tgactggatc ttccatgaaa acggcactat
    15301 tggcatcgat gccggtgcta cgggcatcga agcggtgaaa ggtgttaaag cgaaaaccat
    15361 gcacgatgag acggcaaaag atgacacgcg ctacggcacg cttatcgatc acaatatcgt
    15421 gggtactaca caccaacata tttataattt ccgcctcgat ctggatgtag atggcgagaa
    15481 taacagcctg gtggcgatgg acccagtggt aaaaccgaat actgccggtg gcccacgcac
    15541 cagtaccatg caagttaatc agtacaacat cggcaatgaa caggatgccg cacagaaatt
    15601 tgatccgggc acgattcgtc tgttgagtaa cccgaacaaa gagaaccgca tgggcaatcc
    15661 ggtttcctat caaattattc cttatgcagg tggtactcac ccggtagcaa aaggtgccca
    15721 gttcgcgccg gacgagtgga tctatcatcg tttaagcttt atggacaagc agctctgggt
    15781 aacgcgttat catcctggcg agcgtttccc ggaaggcaaa tatccgaacc gttctactca
    15841 tgacaccggt cttggacaat acagtaagga taacgagtcg ctggacaaca ccgacgccgt
    15901 tgtctggatg accaccggca ccacacatgt ggcccgcgcc gaagagtggc cgattatgcc
    15961 gaccgaatgg gtacatactc tgctgaaacc atggaacttc tttgacgaaa cgccaacgct
    16021 aggggcgctg aagaaagata agtgattgtt tcagacaaaa aaacggcacc aggtgccgtt
    16081 ttttacttat gagcgaacca gattaatacc gtacacacac cgacttagtt tcacaccaac
    16141 cgtccagcca gtcggggcca aaatcacggc ccgttcctga ctgcttcatc ccaccaaacg
    16201 gtaagttagc gtcaattaag gtatggctgt ttacccacac cgtccctgcc tgtaagcgat
    16261 cgctatattc cagagcctgg gagagatttt gcgtccagac actggcagtt aagccatatt
    16321 ccgtgtcgtt tgccagttgt aacgcctctt ctccatccgc tactcgcacc aggtttacca
    16381 ccggaccaaa cacctcttca cgagttaagc gcaatttagc atcgggattt accaccagcg
    16441 ttggcgcaac ataatacccc tctccggctg gtccattcga cccgcgaatc agctctgctt
    16501 gctgtgcctg cgcatcgtcg aggaatgaac acactttgtc gcagtgcgca cgagaaacca
    16561 aagggttaat ctgtgcaaca ggtgacatcc ccggtcccac ttgcaacgat tttaccgcct
    16621 gctcaaatcc actaaccagc gtgtcaaaca acggcgcttc aatataaatt cgcgaactgg
    16681 cggcgcatac ttgcccttga ttcaggaagc ttccggtcat caagccttca ataacccatt
    16741 gcggatcagc atcttttaat acaattgccg ggtttttacc gcccagttcc agcgttacac
    16801 gcgttaagtg atcagcagca gttctggcaa taccttttcc cgtcgcggtt gaaccggtaa
    16861 aactgatttt cgcaacatga ggatgtgacg tcagggccgc gccgcataca gcacctgacc
    16921 cggtgacgac attaaaaacg ccatcaggga taccagcctc gctggccagt tccgccacgc
    16981 gcaacatcgt cagtggcgtg gtttccgaag gcttaatcac gattgaacag cctgctgcca
    17041 gtgctggcat caccttccac ataccaatca tcaacggaaa gttccatggc acaattcccg
    17101 ccactacgcc aaccggctct ttacgcgtcc aggcctgata acgcgccccc tggggtaagg
    17161 gaatcgacaa gtccagcgtt ttacccacga ttttggtcgt taacccggcg gtataacgca
    17221 tccagttcag cgtacagccc acttcaaaag cacgggaaat ggcaattgac ttgccttgct
    17281 ccagggtttc cagttgcgcc agctcctcac tgtgctgctc caccagatca gcaaaacgta
    17341 gcagaatacg ttcacgctct gcgggtaatc gcccggccca gcgacgcgag acaaaggccc
    17401 gccaggcaga catgactgcg ttatctacat ccgcttcgtt ggcatcagca gtagacgcaa
    17461 tttcttgccc ggtggccgga tcaaagatcg ccaaccgttt ttcactttgt gcggggccag
    17521 gacgaccatc aatataaaga ccgtgttgac gatcgagaaa ctgttggacc tggcttaata
    17581 ctgctacatg cggctctgtc atcacttttc cttattattt acccagtgtg atttcagtgt
    17641 acgcagcgac aagaaaagtc acttttttcg ctgtgacatt cgctttgtca gctgtgacaa
    17701 gctccgcaaa tcgtgacaat aaccgcttat gtctctatgc ctgacaagac ttatttccta
    17761 tagtcaggct cattagcttc gtttattgca acacaaatgc aacaataaaa atacatttca
    17821 cagagcgaaa acgtgccatg aaccccgcag tggataatga gtttcagcaa tggctttccc
    17881 aaatcaatca ggtatgcgga aattttaccg gacgcctgct gactgagcgt tacacgggtg
    17941 tactggacac gcattttgcc aaaggactaa agctgagtac cgtgacaacc agcggggtga
    18001 atttatcccg cacctggcag gaagtaaaag gcagcgacga tgcctggttt tacaccgttt
    18061 ttcagcttag tggtcaggca ataatggagc aggatgagcg tcaggtgcag attggcgctg
    18121 gcgatattac gttactcgat gcctcacgcc cctgttcgct ttactggcag gagtcttcta
    18181 aacagatttc attacttttg ccacgcactc tgctggaaca atattttccc catcaaaaac
    18241 ctgtctgcgc agaaagactg gacgctgact tacccatggt gcaactcagt catcgcctgt
    18301 tacaggagag catgaataat ccggcacttt ctgaaacaga aagtgaagct gcgctacagg
    18361 cgatggtgtg tctgctgcgc ccggtacttc atcagcggga atctgttcaa cctcgtcgtg
    18421 aacgtcagtt tcaaaaagtg gttacgttga tagacgataa tattcgcgaa gagatattac
    18481 gcccggagtg gatagccgga gagacaggta tgtcagtacg tagtttgtac cgaatgtttg
    18541 ccgataaagg tttggtagtc gcgcaatata ttcgtaaccg tcgtctcgat ttttgtgcag
    18601 atgcgattcg ccatgccgca gatgatgaaa aactggcagg catcggcttt cattggggat
    18661 tttctgacca gagtcatttt tcaacggtat ttaagcaacg ctttgggatg acgccaggcg
    18721 agtatcgacg taaattccgc taactaattg gcgttgcatg tactgcaacg ccaattagtt
    18781 aaaacagata tttgactatg catttttcag ggcaaaaggc aatttgacag gagtttttga
    18841 atattcacct tgtttcagga aaatagatca atcgccttct cctgtagcgt tatcccgata
    18901 ttgcggtttt gctattaaaa ttttcgcacc catttaccgt ttatcccttg tacatattcc
    18961 cccggtttgg cccgagctac gagcttttgc ccggcgagtt tcgcgatatc atctaccgac
    19021 acattatttt gctttgccag ttgttggtaa ctcgctttac gttcggcatt aatgtcggct
    19081 actaatttct ctgtttcagc atccgttttc agcgcaacca gataaccgta aaatgtttca
    19141 cctacccgcc cctgagttct ggcttcatcc agagtcaatg ccattacatt gctgcttacc
    19201 agcccaacaa gaaacgcaca aagaagtaat gttttcttca tcatcacctc agaaaagatc
    19261 gctacgagtt tcaagcagct cttcgacatc tttgtctgcc ttgatgatga tctcatgctc
    19321 aattttaacg ttcatattga tagtgatcgg ttccttaggt gcagcgactt caatgcgagg
    19381 cgtacagcca accagcataa aagatgacgt caacgcagcc agtaaaattt tcattgtttt
    19441 tcctcacact cttttccttg cggacagtca tttcccggca gacgtgcgtt ctgctccagc
    19501 catgcctgga gattatcgcc aaagcgtaaa ctgcgccaca gcgtaaaaat attctcttca
    19561 tgatggtaat taaggtttac cgtaccgctt ttaccatcaa cgcgactggt acctgtaatg
    19621 ttggcctgca tggttaataa accgagatta tctaaattaa tttttgtcga tgaacggcta
    19681 atttccatat agcgcaacca gttaattgct gaacccgcag tcatattgtc ttttaccacc
    19741 gcatccgcag tgtctttatc cagtcgcaat gtcatcggcc cgctattcgc cagccagcca
    19801 tctttcacaa tccatttttc attgttcagc cataacggca gtgcaccact aaatgccccg
    19861 gacatggcga attgtttcgg attgacggcg ctaaccagtt cgctggatga gagattattc
    19921 agccgcaaca gcgccgggtc atgttgcggc atacgtaatt gtttcatcag tacgttaccg
    19981 cctaacacat cgacgctaac atcagtcaac agcaagggtt cttcttcagt ccacggataa
    20041 cgcccttgca aatcagccgt aatatttttc gctgtcacca gattaatcac ttcggcaatt
    20101 cgcaacgtaa cggggccgcg agtccccaga tgccaggctc catcggcaaa acggaaaggc
    20161 aggacaaaat cgacaccgtt aacctgatta tctggcatcc aggcactacc gcctttcaac
    20221 acgccgtgtc ctcccgcgcg gaatccttgt tcaggcgcag cagaaaatgc aacctgagca
    20281 tacagttcac catcgcgtaa gttcatcttc cagtcgggtg gcaccagcgg ctggaatacg
    20341 gtcagtgatt gtttaggcca ccaggcgtta ccgcgcagac gaataccgtc ccagcgacca
    20401 tttacccgaa ccgggccaat ctcaccagca tgtaaatcgc ctttaaagag gaaataggta
    20461 ggatcgcgcc catcgacgct aaattttaag gttgatggcg gtaacacact gccgccagtg
    20521 aacagcgttt gcccggcgtc cagtgacagc gcgccgctaa aggagggatg ctgtgcgtca
    20581 cgtacccaga cgatgggctt gtcgagaatt aatcgcggct tttctaccgt catcgtaccg
    20641 tattgtaact ggtcgaaacc ggtggagaga tcggtcagcg taatcgtgct gtcatgccac
    20701 tcaccttttc ctgcgacatc ccaggtggca ttcatcggtg taaaactccc ttttccccag
    20761 tagcgccact gccagcggcc agcgtcaggg agaaaatcat tcgccagccc atccatatgc
    20821 agcacgaaat cgcccagttc attttcatgc gcctgcaaga tggcctgcaa acgtccgtca
    20881 acaccacgtt gggtgacttt tacacccgct aaaggccagc ggatttcatc gatgtccagc
    20941 gaatcgatga ctcttccctt tgaacgaagt aacgcgcctg gctcaaaggt cagcgttggg
    21001 tcagacagac ttccacttag ctgcgcaggt aaacgggcat ataaaatgag gtccgcctgt
    21061 ttcgcttcac cggtcagctg cagaggcagc tgactgttat ccatgcttaa ttttcctggg
    21121 ccaaaattaa gcaccgcgtt gcccttaccc gcttgcccct gggtcagcac actcagtcgt
    21181 ccgctgacca gagcgttctc aagccctgcc tgccagttgt cgactttgac acccagtcgg
    21241 ccactcaaag gaaaacctgc atacggccag ctccagcgac catcgcttac ggtcaattgt
    21301 tgacgagtaa tttgccacgg caaatcgagc aacggatcgc cgttatcccg tgccagcacg
    21361 atcaattgcc cgctattttc ctgccagtcc agctcggcat ccaccagtga cggttcctgc
    21421 ggcaagttta acgtcgcagt agcatgccca cttacaggaa gtccatccgg cacgagcggc
    21481 atagcaaatt cccccaccag ttttaccggc ggctgatttt caaacgcgac gacatccagt
    21541 tcgctgactg taagttgttg ccctttcagc tggccttgaa atttaacttt ttcgccctga
    21601 taacgcagtt gctggatatc agaggttaat gcgagagaga gttttccctg ccattcctgc
    21661 cagggagaaa aaatcagttt atcgatattg atccaggtgt taggcagcat ggcctgccac
    21721 tgcgcgagtg tttttggagc ggctggcgat tgctccgtct gcggcaattt cgccagacaa
    21781 gcagaatcaa gttctaccgt gccgacgttc aataaccagc ggctgggatg tgaaaggctg
    21841 gcgttggtga tatgcgcaag ctgacaatct cccaccagat aacggagatc gggaatgatt
    21901 aaacctttac gcgtaatgcg tgggctttca tctaatgcaa tacgtgtccc gagcggtagc
    21961 cagatgcccg ccagcgtggg aacccacagc ccgagcgtca tcagcagcgt caacggcaca
    22021 agaataatca gtaataacag cgcgagaacg gctttatatt tacccagcat gggtagttaa
    22081 tatcctgatt tagcgaaaaa ttaagcattc aatacgggta ttgtggcatg tttaaccgtt
    22141 cagttgaagg ttgcgcctac actaagcata gttgttgatg aatttttcaa tatcgccata
    22201 gctttcaatt aaatttgaaa ttttgtaaaa tatttttagt agcttaaatg tgattcaaca
    22261 tcactggaga aagtcttatg aaactcgccg tttatagcac aaaacagtac gacaagaagt
    22321 acctgcaaca ggtgaacgag tcctttggct ttgagctgga attttttgac tttctgctga
    22381 cggaaaaaac cgctaaaact gccaatggct gcgaagcggt atgtattttc gtaaacgatg
    22441 acggcagccg cccggtgctg gaagagctga aaaagcacgg cgttaaatat atcgccctgc
    22501 gctgtgccgg tttcaataac gtcgaccttg acgcggcaaa agaactgggg ctgaaagtag
    22561 tccgtgttcc agcctatgat ccagaggccg ttgctgaaca cgccatcggt atgatgatga
    22621 cgctgaaccg ccgtattcac cgcgcgtatc agcgtacccg tgatgctaac ttctctctgg
    22681 aaggtctgac cggctttact atgtatggca aaacggcagg cgttatcggt accggtaaaa
    22741 tcggtgtggc gatgctgcgc attctgaaag gttttggtat gcgtctgctg gcgttcgatc
    22801 cgtatccaag tgcagcggcg ctggaactcg gtgtggagta tgtcgatctg ccaaccctgt
    22861 tctctgaatc agacgttatc tctctgcact gcccgctgac accggaaaac tatcatctgt
    22921 tgaacgaagc cgccttcgaa cagatgaaaa atggcgtgat gatcgtcaat accagtcgcg
    22981 gtgcattgat tgattctcag gcagcaattg aagcgctgaa aaatcagaaa attggttcgt
    23041 tgggtatgga cgtgtatgag aacgaacgcg atctattctt tgaagataaa tccaacgacg
    23101 tgatccagga tgacgtattc cgtcgcctgt ctgcctgcca caacgtgctg tttaccgggc
    23161 accaggcatt cctgacagca gaagctctga ccagtatttc tcagactacg ctgcaaaact
    23221 taagcaatct ggaaaaaggc gaaacctgcc cgaacgaact ggtttaatct tgccgctccc
    23281 ctgcattcca ggggagctga ttcagataat ccccaatgac ctttcatcct ctattcttaa
    23341 aatagtcctg agtcagaaac tgtaattgag aaccacaatg aagaaagtag ccgcgtttgt
    23401 tgcgctaagc ctgctgatgg cgggatgtgt aagtaatgac aaaattgctg ttacgccaga
    23461 acagctacag catcatcgct ttgtgctgga aagcgtaaac ggtaagcccg tgaccagcga
    23521 taaaaatccg ccagaaatca gctttggtga aaaaatgatg atttccggca gcatgtgtaa
    23581 ccgctttagc ggtgaaggca aactgtctaa tggtgaactg acagccaaag ggctggcaat
    23641 gacccgtatg atgtgcgcta acccgcagct taatgaactc gataacacca ttagcgaaat
    23701 gctgaaagaa ggtgcacaag tggatctgac cgcgaaccag ttaacgctgg cgaccgcaaa
    23761 acagacatta acttataagc tggcggattt aatgaattaa tagctgccac agctcccggc
    23821 ggcaagtgac tgttcgctac agcgtttgcc gttgggtaat gcacacatcc caatcgccgt
    23881 accatccagt tgacgggcaa cagaaagcga accgccgatc attgcacaat ttgcttctcc
    23941 actactggac atcgacgctt ttaaacctgg cgctacgtgc gcggcagtcg cctgctgaac
    24001 aggttcacta ctacacgccg acaacaataa agcggcacac cctacccaaa acgctgctcg
    24061 catcttttct tcctctgatc ttcaagccaa acgacaccgc cataaataat aggcagcaca
    24121 gagggcggcg tcgagagctg tcctgcgcgt tgccccgcat ttttactttt ttatggctat
    24181 ttttttgccc tctgtttgat caaaacattc attacgctga tgtgggggac acaaaagcga
    24241 aaatgcagaa gaaagccatt tgctaaaatt gaaagattac tactgggcgc gcagcaattt
    24301 cgtgcgcccc tcatttgcgc aatgtaaggg tgtcatatga ttactattga cggtaatggc
    24361 gcggttgctt cggtcgcatt tcgcaccagt gaagttatcg ccatctaccc tattaccccc
    24421 agttccacga tggcagaaca ggctgatgcc tgggccggaa acggcttaaa gaacgtttgg
    24481 ggagacacac cacgcgtggt tgaaatgcag tcggaagcgg gtgctatcgc taccgtgcat
    24541 ggcgctttgc agacgggtgc cctttcaaca tcgtttacgt catcgcaggg tttgctgctg
    24601 atgatcccga cgctgtacaa actggcaggc gaactaacac cgtttgtcct gcatgtagcg
    24661 gcacgtaccg ttgccacaca tgcactctct atttttggcg atcattccga cgttatggcg
    24721 gtgcgccaga cgggttgcgc gatgttgtgt gcagcaaacg tccaggaagc gcaagacttt
    24781 gctctcattt cgcaaatcgc gacgctgaaa agccgcgtgc catttattca tttctttgat
    24841 ggtttccgca cgtcccacga aatcaataaa attgtcccgc tggccgatga cacgattctt
    24901 gatctcatgc cgcaggtcga aattgatgct catcgcgccc gggcactcaa cccggaacat
    24961 ccggtgatcc gcggtacgtc cgccaatcct gacacttatt tccagtctcg cgaagccacc
    25021 aacccatggt acaacgcggt ctatgaccat gttgaacagg cgatgaatga tttctctgcc
    25081 gcgacaggtc gtcagtatca gccgtttgaa tattacgggc atccgcaagc ggaacgggtg
    25141 attatcctga tgggctctgc cattggcacc tgtgaagaag tggttgatga attgctaacc
    25201 cgtggcgaaa aagttggcgt gctgaaagtt cgcctgtacc gccccttctc cgctaaacat
    25261 ttactgcaag ctctgccggg atccgtacgc agcgtggcgg tactggacag aaccaaagaa
    25321 cccggtgccc aggcagaacc gctctatctg gatgtaatga ccgcactggc agaagccttt
    25381 aataatggcg agcgcgaaac tctgccccgt gtcattggtg ggcgctatgg tctttcatcc
    25441 aaagaatttg gcccagactg tgtactggcg gtatttgccg agctcaacgc ggctaaaccg
    25501 aaagcgcgct ttacggttgg tatttacgat gatgtgacca atctgtcact gccgttgccg
    25561 gaaaacaccc tgccaaactc ggcgaaactg gaagccttgt tttatggcct tggtagtgat
    25621 ggcagcgttt ccgcgaccaa aaacaatatc aagattatcg gtaattccac gccgtggtac
    25681 gcacagggct attttgttta cgactccaaa aaggcgggcg gcctgacggt ttctcacctt
    25741 cgagtgagcg aacagccgat tcgttccgct tatctcattt cccaggctga ttttgttggc
    25801 tgccaccagt tgcagtttat cgataaatat cagatggctg agcgtttaaa acctggcggc
    25861 attttcctgc tcaacacgcc gtacagcgca gatgaagtgt ggtcgcgctt gccgcaagaa
    25921 gttcaggccg tgttaaacca gaaaaaagcg cgcttctatg tgattaacgc ggcgaaaatc
    25981 gcccgcgaat gtggcctggc ggcccgtatt aataccgtca tgcagatggc ttttttccat
    26041 ctgacgcaaa ttctgcctgg cgatagcgcc ctcgcagaat tgcagggtgc gattgccaaa
    26101 agttacagta gcaaaggcca ggatctggtg gaacgcaact ggcaggctct ggcgctggcg
    26161 cgtgaatccg tagaagaagt tccgttgcaa ccggtaaatc cgcacagcgc caatcgaccg
    26221 ccagtggttt ccgatgccgc ccctgatttc gtgaaaaccg taaccgctgc gatgctcgcc
    26281 gggcttggtg acgccctccc cgtttcggcg ctgccgccag acggcacctg gccgatgggc
    26341 actacgcgct gggaaaaacg caatatcgcc gaagagatcc ccatctggaa agaggaactc
    26401 tgtacccaat gtaaccactg cgttgccgct tgcccacact cagctattcg cgcaaaagtg
    26461 gtgccgcctg aagcgatgga aaacgcccct gccagcctgc attcgctgga tgtgaaatcg
    26521 cgtgatatgc gcgggcagaa atatgtcttg caggtggcac cggaagattg caccggttgt
    26581 aacctgtgcg tcgaagtttg cccggcgaaa gaccgtcaga atccagagat taaagccatc
    26641 aatatgatgt ctcgcctgga acatgtcgaa gaagagaaaa tcaattacga tttcttcctc
    26701 aacctgccag aaatcgaccg tagcaaactg gaacgtattg atattcgtac atcgcagctg
    26761 attacaccgc tgtttgaata ttcaggtgct tgctccggtt gtggcgagac gccgtatatt
    26821 aaattactga ctcagctcta tggcgaccgg atgttgatcg ctaacgccac tggctgttct
    26881 tcaatttatg gcggtaacct gccctctaca ccgtatacca ccgatgccaa cggtcgtggg
    26941 ccggcatggg cgaactctct atttgaagat aatgccgaat ttggccttgg tttccgcctg
    27001 acggtcgatc aacaccgtgt ccgcgtgctg cgtctgctgg atcaatttgc cgataaaatc
    27061 ccggcggaat tactgacggc gttgaaatca gacgccacgc cagaggttcg tcgtgaacag
    27121 gttgcagctt tacgccagca actcaacgat gttgccgaag cacatgaact gctacgtgat
    27181 gcagatgcac tggtggaaaa atcaatctgg ctgattggtg gtgatggctg ggcttacgat
    27241 atcggctttg gcggtctgga tcatgtattg agtttgacgg aaaacgtcaa cattctggtg
    27301 ctggatacgc aatgctattc caacaccggt ggtcaggcgt cgaaagcgac accgctgggt
    27361 gcagtaacta aatttggcga gcacggcaaa cgtaaagcgc gtaaagatct tggcgtcagt
    27421 atgatgatgt acggtcatgt ttatgtggcg cagatttctc tcggcgcgca gctgaaccag
    27481 acggtgaaag cgattcagga agcggaagcg tatccggggc catcgctgat cattgcttat
    27541 agcccgtgtg aagagcatgg ttacgatctg gcactcagcc acgaccagat gcgccaactc
    27601 acagctaccg gcttctggcc gctatatcgc tttgatccgc gtcgtgccga tgaaggcaaa
    27661 ctgccgctgg ccttggattc acgcccgccg tcagaagcac tggaagaaac gttacttcac
    27721 gagcaacgtt tccgtcggct gaattcgcag cagccagaag tggcagaaca gttatggaaa
    27781 gatgctgcag ctgatttgca aaaacgctat gacttcctgg cacaaatggc cggaaaagcg
    27841 gaaaaaagca acaccgatta aatgctctgg ataaggatta tccaattcta aaaaaaaagc
    27901 ccggacgact gttcgggctt gtctttttat atgttggaaa atcagtggca atgcaatggc
    27961 ccaacagaaa ataaaatctg tgacaataaa ggcatataac
//
LOCUS       DAPOAV010000057        27485 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.057, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000057 DAPOAV010000000
VERSION     DAPOAV010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 27485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27485
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.057"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            115..372
                     /gene="bhsA"
                     /locus_tag="RN951_002780"
     CDS             115..372
                     /gene="bhsA"
                     /locus_tag="RN951_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple stress resistance protein BhsA"
                     /protein_id="HDX2527756.1"
                     /translation="MKNVKTLIAAAILSSMSFASFAAVEVQSTPEGQQKVGTISANAG
                     TNLGSLEEQLAQKADEMGAKSFRITSVTGPNTLHGTAVIYK"
     gene            complement(454..1416)
                     /gene="ldtC"
                     /locus_tag="RN951_002781"
     CDS             complement(454..1416)
                     /gene="ldtC"
                     /locus_tag="RN951_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase LdtC"
                     /protein_id="HDX2527757.1"
                     /translation="MMIKTRFSRWLTFFTFAAAVALALPAKANTWPLPPAGSRLVGEN
                     KFHVVENDGGSLEAIAKKYNVGFLALLQANPGVDPYVPRAGSVLTIPLQTLLPDAPRE
                     GIVINIAELRLYYYPPGKNSVTVYPIGIGQLGGDTLTPTMVTTVSDKRANPTWTPTAN
                     IRARYKAQGIELPAVVPAGPDNPMGHHAIRLAAYGGVYLLHGTNADFGIGMRVSSGCI
                     RLRDDDIKTLFSQVTPGTKVNIINTPIKVSAEPNGARLVEVHQPLSEKIDDDPQLLPI
                     TLNSAMQSFKDAAQTDAEVMQHVMDVRSGMPVDVRRHQVSPQTL"
     gene            complement(1560..5006)
                     /gene="mfd"
                     /locus_tag="RN951_002782"
     CDS             complement(1560..5006)
                     /gene="mfd"
                     /locus_tag="RN951_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HDX2527758.1"
                     /translation="MPEQYRYTLPVKAGEQRLLGELTGAACATLVAEIAERHAGPVVL
                     IAPDMQNALRLHDEISQFTDQMVMNLADWETLPYDSFSPHQDIISSRLSTLYQLPTMQ
                     RGVLIVPVNTLMQRVCPHSFLHGHALVMKKGQRLSRDALRTQLDSAGYRHVDQVMEHG
                     EYATRGALLDLFPMGSELPYRLDFFDDEIDSLRVFDVDSQRTLEEVEAINLLPAHEFP
                     TDKAAIELFRSQWRDTFEVKRDPEHIYQQVSKGTLPAGIEYWQPLFFSEPLPPLFSYF
                     PANTLLVNTGDLETSAERFQADTLARFENRGVDPMRPLLPPQSLWLRVDELFSELKNW
                     PRVQLKTEHLPTKAANANLGFQKLPDLAVQAQQKAPLDALRKFLETFDGPVVFSVESE
                     GRREALGELLARIKIAPQRIMRLDEASDRGRYLMIGAAEHGFVDTVRNLALICESDLL
                     GERVARRRQDSRRTINPDTLIRNLAELHIGQPVVHLEHGVGRYAGMTTLEAGGITGEY
                     LMLTYANDAKLYVPVSSLHLISRYAGGAEENAPLHKLGGDAWSRARQKAAEKVRDVAA
                     ELLDIYAQRAAKEGFAFKHDREQYQLFCDSFPFETTPDQAQAINAVLSDMCQPLAMDR
                     LVCGDVGFGKTEVAMRAAFLAVDNHKQVAVLVPTTLLAQQHYDNFRDRFANWPVRIEM
                     ISRFRSAKEQTQILAEVAEGKIDILIGTHKLLQSDVKFKDLGLLIVDEEHRFGVRHKE
                     RIKAMRANVDILTLTATPIPRTLNMAMSGMRDLSIIATPPARRLAVKTFVREYDSMVV
                     REAILREILRGGQVYYLYNDVENIQKAAERLAELVPEARIAIGHGQMRERELERVMND
                     FHHQRFNVLVCTTIIETGIDIPTANTIIIERADHFGLAQLHQLRGRVGRSHHQAYAWL
                     LTPHPKAMTTDAQKRLEAIASLEDLGAGFALATHDLEIRGAGELLGEEQSGSMETIGF
                     SLYMELLENAVDALKAGREPSLEDLTSQQTEVELRMPSLLPDDFIPDVNTRLSFYKRI
                     ASAKTENELEEIKVELIDRFGLLPDPARTLLDIARLRQQAQKLGIRKLEGNEKGGVIE
                     FAEKNHVNPARLIGLLQKQPQHYRLDGPTRLKFIQDLSERKTRIEWVRQFMRELEENA
                     IA"
     gene            complement(5134..6207)
                     /locus_tag="RN951_002783"
     CDS             complement(5134..6207)
                     /locus_tag="RN951_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HDX2527759.1"
                     /translation="MKQKELWINQIKGLCICLVVIYHSVITFYPHLTTFQHPLSEVLS
                     KCWIYFNLYLAPFRMPVFFFISGYLIRRYIDSVPWGNCLDKRIWNIFWVLALWGVVQW
                     LALSALNQWLAPERDLSNASNAAYADSTGEFLHGMITASNSLWYLYALIVYFVVCKIF
                     SRLALPLFALFVLLSVAVNFVPTPWWGMNSVIRNLPYYSLGAWFGATIMTCVKEVPLR
                     RHLLMASLLTVLAVGAWLFTISLLLSLVSIVVIMKLFYQYEQRFGMRSTSLLNVIGSN
                     TIAIYTTHRILVEIFSLTLLAQMNAARWSPQVELTLLLVYPFVSLFICTVAGLLVRKL
                     SQRAFSDLLFSPPSLPAAVSYSR"
     gene            6469..7668
                     /gene="lolC"
                     /locus_tag="RN951_002784"
     CDS             6469..7668
                     /gene="lolC"
                     /locus_tag="RN951_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004976588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolC"
                     /protein_id="HDX2527760.1"
                     /translation="MYQPVALFIGLRYMRGRAADRFGRFVSWLSTIGITLGVMALVTV
                     LSVMNGFERELQNNILGLMPQAILSSEHGSLNPQQLPETAVKLDGVNRVAPITTGDVV
                     LQSARSVAVGVMLGIDPAQKDPLTPYLVNVKQTDLEPGKYNVILGEQLASQLGVNRGD
                     QIRVMVPSASQFTPMGRIPSQRLFNVIGTFAANSEVDGYEMLVNIEDASRLMRYPAGN
                     ITGWRLWLDEPLKVDSLSQQKLPEGSKWQDWRDRKGELFQAVRMEKNMMGLLLSLIVA
                     VAAFNIITSLGLMVMEKQGEVAILQTQGLTPRQIMMVFMVQGASAGIIGAILGAALGA
                     LLASQLNNLMPIIGVLLDGAALPVAIEPLQVIVIALVAMAIALLSTLYPSWRAAATQP
                     AEALRYE"
     gene            7661..8362
                     /gene="lolD"
                     /locus_tag="RN951_002785"
     CDS             7661..8362
                     /gene="lolD"
                     /locus_tag="RN951_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415635.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter
                     ATP-binding protein LolD"
                     /protein_id="HDX2527761.1"
                     /translation="MNKILLQCDNLCKRYQEGSVQTDVLHNVSFSVGEGEMMAIVGSS
                     GSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAELRNQKLGFIYQFHHLLPDF
                     TALENVAMPLLIGKKKPAEINSRALEMLKAVGLDHRANHRPSELSGGERQRVAIARAL
                     VNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLEM
                     RDGRLTAELSLMGAE"
     gene            8362..9606
                     /gene="lolE"
                     /locus_tag="RN951_002786"
     CDS             8362..9606
                     /gene="lolE"
                     /locus_tag="RN951_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolE"
                     /protein_id="HDX2527762.1"
                     /translation="MAMPLSLLIGLRFSRGRRRGGMVSLISVISTIGIALGVAVLIVG
                     LSAMNGFERELNNRILAVVPHGEIEAVDQPWTNWQEALDHVQKVPGIAAAAPYINFTG
                     LVESGANLRAIQVKGVNPQQEQRLSALPSFVQGDAWRNFKAGEQQIIIGKGVADALKV
                     KQGDWVSIMIPNSNPEHKLMQPKRVRLHVAGILQLSGQLDHSFAMIPLADAQQYLDMG
                     SSVSGIALKMTDVFNANKLVRDAGEVTNSYVYIKSWIGTYGYMYRDIQMIRAIMYLAM
                     VLVIGVACFNIVSTLVMAVKDKSGDIAVLRTLGAKDGLIRAIFVWYGLLAGLFGSLCG
                     VIIGVVVSLQLTPIIEWIEKLIGHQFLSSDIYFIDFLPSELHWLDVFYVLVTALLLSL
                     LASWYPARRASNIDPARVLSGQ"
     gene            9635..10546
                     /gene="nagK"
                     /locus_tag="RN951_002787"
     CDS             9635..10546
                     /gene="nagK"
                     /locus_tag="RN951_002787"
                     /EC_number="2.7.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HDX2527763.1"
                     /translation="MYYGFDIGGTKIALGVFDSGRQLQWEKRVPTPRDSYDAFLDAVC
                     ELVAEADQRFGCKGSVGIGIPGMPETEDGTLYAANVPAASGKPLRADLSARLDRDVRL
                     DNDANCFALSEAWDDEFTQYPLVMGLILGTGVGGGLIFNGKPITGKSYITGEFGHMRL
                     PVDALTMMGLDFPLRRCGCGQHGCIENYLSGRGFAWLYQHYYHQPLQAPEIIALYDQG
                     DEQARAHVERYLDLLAVCLGNILTIVDPDLVVIGGGLSNFPAITTQLADRLPRHLLPV
                     ARVPRIERARHGDAGGMRGAAFLHLTD"
     gene            10562..11401
                     /gene="cobB"
                     /locus_tag="RN951_002788"
     CDS             10562..11401
                     /gene="cobB"
                     /locus_tag="RN951_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415638.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HDX2527764.1"
                     /translation="MLSRRGHRLSRFRKNKRRLRERLRQRIFFRDKVVPEAMEKPRVL
                     VLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFDRDPELVQAFYNARRRQLQQP
                     EIQPNAAHLALAKLQDALGDRFLLVTQNIDNLHERAGNTNVIHMHGELLKVRCSQSGQ
                     VLDWTGDVTPEDKCHCCQFPAPLRPHVVWFGEMPLGMDAIYMALSMADIFIAIGTSGH
                     VYPAAGFVHEAKLHGAHTVELNLEPSQVGNEFAEKYYGPASQVVPEFVEKLLKGLKAG
                     SIA"
     gene            complement(11521..12309)
                     /locus_tag="RN951_002789"
     CDS             complement(11521..12309)
                     /locus_tag="RN951_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HDX2527765.1"
                     /translation="MKKFIILLSLLILLPLTAASKPLIPIMKTLFTDVTGTVPDAEEI
                     AHKAELFRQQTGIAPFIVVLPDINNEASLRQNGKAMLAHASSSLSDVKGSVLLLFTTR
                     EPRLIMITNGQVESGLDDKHLGLLIENHTLAYLNADLWYQGINNALAVLQAQILKQST
                     PPLTYYPHPGQQHENAPPGSTNTLGFIAWAATFILFSRIFYYTTRFIYALKFAVAMTI
                     ANMGYQALCLYIDNSFAITRISPLWAGLIGVCTFIAALLLTSKR"
     gene            complement(12306..12767)
                     /locus_tag="RN951_002790"
     CDS             complement(12306..12767)
                     /locus_tag="RN951_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415640.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3592 domain-containing protein"
                     /protein_id="HDX2527766.1"
                     /translation="MSQDSKVFFRIFLGIGLVLILISVVVFYNQFTYSKDAIHTEGVI
                     VDTVWHSSHSHRTGKDGSWYPVVAFRPTPDYTLIFNSSIGSDFYEDSEGDKVNVYYSP
                     GHPEKAEINNPWVNFFKWGFIGIMGVIFIAVGLLISMPSSKKSRRKRKSRP"
     gene            complement(12825..13871)
                     /gene="potD"
                     /locus_tag="RN951_002791"
     CDS             complement(12825..13871)
                     /gene="potD"
                     /locus_tag="RN951_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotD"
                     /protein_id="HDX2527767.1"
                     /translation="MKKWSRHLLAAGALALGMSAAHADDNNTLYFYNWTEYVPPGLLE
                     QFTKETGIKVIYSTYESNETMYAKLKTYKDGAYDLVVPSTYYVDKMRKEGMIQKIDKS
                     KLTNFSNLDPDMLNKPFDPNNDYSIPYIWGATAIGVNGDAVDPKSVTSWADLWKPEYK
                     GSLLLTDDAREVFQMALRKLGYSGNTTDPKEIEAAYNELKKLMPNVAAFNSDNPANPY
                     MEGEVNLGMIWNGSAFVARQAGTPIDVVWPKEGGIFWMDSLAIPANAKNKEGALKLIN
                     FLLRPDVAKQVAETIGYPTPNLAARKLLSPEVANDKTLYPDAETIKNGEWQNDVGAAS
                     SIYEEYYQKLKAGR"
     gene            complement(13868..14662)
                     /gene="potC"
                     /locus_tag="RN951_002792"
     CDS             complement(13868..14662)
                     /gene="potC"
                     /locus_tag="RN951_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotC"
                     /protein_id="HDX2527768.1"
                     /translation="MIGRLLRGGFMTAIYAYLYIPIIILIVNSFNSSRFGINWQGFTT
                     KWYSLLMNNDSLLQAAQHSLTMAVFSATFATLIGSLTAVALYRYRFRGKPFVSGMLFV
                     VMMSPDIVMAISLLVLFMLLGIQLGFWSLLFSHITFCLPFVVVTVYSRLKGFDVRMLE
                     AAKDLGASEFTILRKIILPLAIPAVAAGWVLSFTLSMDDVVVSSFVTGPSYEILPLKI
                     YSMVKVGVSPEVNALATILLVLSLVMVIASQLIARDKTKGNTGDVK"
     gene            complement(14659..15516)
                     /gene="potB"
                     /locus_tag="RN951_002793"
     CDS             complement(14659..15516)
                     /gene="potB"
                     /locus_tag="RN951_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotB"
                     /protein_id="HDX2527769.1"
                     /translation="MKNTSKFQNVVIVTIVGWLVLFVFLPNLMIIGTSFLTRDDASFV
                     KMVFTLDNYTRLLDPLYFEVLLHSLNMALIATLACLVLGYPFAWFLAKLPHKVRPLLL
                     FLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTPIRIMFTPSAVIIGLVYI
                     LLPFMVMPLYSSIEKLDKPLLEAARDLGASKLQTFIRIIIPLTMPGIIAGCLLVMLPA
                     MGLFYVSDLMGGAKNLLIGNVIKVQFLNIRDWPFGAATSITLTIVMGLMLLVYWRASR
                     LLNKKVELE"
     gene            complement(15500..16636)
                     /gene="potA"
                     /locus_tag="RN951_002794"
     CDS             complement(15500..16636)
                     /gene="potA"
                     /locus_tag="RN951_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     ATP-binding protein PotA"
                     /protein_id="HDX2527770.1"
                     /translation="MGQSKKLNKQPSSLSPLVQLAGIRKCFDGKEVIPQLDLTINNGE
                     FLTLLGPSGCGKTTVLRLIAGLETVDSGRIMLDNEDITHVPAENRYVNTVFQSYALFP
                     HMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLETFAQRKPHQLSGGQQQRVAIAR
                     AVVNKPRLLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRI
                     VVMRDGRIEQDGTPREIYEEPKNLFVAGFIGEINMFNATVIERLDEQRVRANVEGREC
                     NIYVNFAVEPGQKLHVLLRPEDLRVEEINDDNHAEGLIGYVRERNYKGMTLESVVELE
                     NGKMVMVSEFFNEDDPDFDHSLDQKMAINWVESWEVVLADEEHK"
     gene            16886..18112
                     /gene="pepT"
                     /locus_tag="RN951_002795"
     CDS             16886..18112
                     /gene="pepT"
                     /locus_tag="RN951_002795"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HDX2527771.1"
                     /translation="MDKLLERFLNYVSLDTQSKAGVRQVPSTEGQWKLLHLLKEQLEE
                     MGLINVTLSEKGTLMATLPANVPGDIPAIGFISHVDTSPDCSGKNVNPQIVENYRGGD
                     IALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGIAEIMTALAVLQQKKI
                     PHGDIRVAFTPDEEVGKGAKHFDVDAFDARWAYTVDGGGVGELEFENFNAASVNIKIV
                     GNNVHPGTAKGVMVNALSLAARIHAEVPADESPEMTEGYEGFYHLASMKGTVERADMH
                     YIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILD
                     IAQQAMRDCDIEPELKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEK
                     AVQVIVRIAELTAQRK"
     gene            complement(18161..19282)
                     /gene="roxA"
                     /locus_tag="RN951_002796"
                     /gene_synonym="ycfD"
     CDS             complement(18161..19282)
                     /gene="roxA"
                     /locus_tag="RN951_002796"
                     /gene_synonym="ycfD"
                     /EC_number="1.14.11.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415646.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[50S ribosomal protein L16]-arginine
                     3-hydroxylase"
                     /protein_id="HDX2527772.1"
                     /translation="MEYQLTLNWPDFLERHWQKRPVVLKRGFNNFIDPISPDELAGLA
                     MESEVDSRLVSHQDGKWQVSHGPFESYDHLGETNWSLLVQAVNHWHEPTAALMRPFRE
                     LPDWRIDDLMISFSVPGGGVGPHLDQYDVFIIQGTGRRRWRVGEKLQMKQHCPHPDLL
                     QVDPFEAIIDEELEPGDILYIPPGFPHEGYALENAMNYSVGFRAPNTRELISGFADYV
                     LQRELGGNYYSDPDVPPRAHPADVLPQEMDKLREMMLELINQPEHFKQWFGEFISQSR
                     HELDIAPPEPPYQPDEIYDALKQGEVLVRLGGLRVLRIGDDVYANGEKIDSPHRPALD
                     ALASNIALTAENFGDALEDPSFLAMLAALVNSGYWFFEG"
     gene            complement(19358..20818)
                     /gene="phoQ"
                     /locus_tag="RN951_002797"
     CDS             complement(19358..20818)
                     /gene="phoQ"
                     /locus_tag="RN951_002797"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PhoQ"
                     /protein_id="HDX2527773.1"
                     /translation="MKKLLRLFFPLSLRVRFLLATAAVVLVLSLAYGMVALIGYSVSF
                     DKTTFRLLRGESNLFYTLAKWENNKLHVELPENIDKQSPTMTLIYDENGQLLWAQRDV
                     PWLMKMIQPDWLKSNGFHEIEADVNDTSLLLSGDHSIQQQLQEVREDDDDAEMTHSVA
                     VNVYPATSRMPKLTIVVVDTIPVELKSSYMVWSWFIYVLSANLLLVIPLLWVAAWWSL
                     RPIEALAKEVRELEEHNRELLNPATTRELTSLVRNLNRLLKSERERYDKYRTTLTDLT
                     HSLKTPLAVLQSTLRSLRSEKMSVSDAEPVMLEQISRISQQIGYYLHRASMRGGTLLS
                     RELHPVAPLLDNLTSALNKVYQRKGVNISLDISPEISFVGEQNDFVEVMGNVLDNACK
                     YCLEFVEISARQTDEHLYIVVEDDGPGIPLSKREVIFDRGQRVDTLRPGQGVGLAVAR
                     EITEQYEGKIVAGESMLGGARMEVIFGRQHSAPKDE"
     gene            complement(20818..21489)
                     /gene="phoP"
                     /locus_tag="RN951_002798"
     CDS             complement(20818..21489)
                     /gene="phoP"
                     /locus_tag="RN951_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator PhoP"
                     /protein_id="HDX2527774.1"
                     /translation="MRVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHI
                     PDIAIVDLGLPDEDGLSLIRRWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKP
                     FHIEEVMARMQALMRRNSGLASQVISLPPFQVDLSRRELSINDEVIKLTAFEYTIMET
                     LIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPQEVITTVRGQGY
                     LFELR"
     gene            complement(21658..23028)
                     /gene="purB"
                     /locus_tag="RN951_002799"
     CDS             complement(21658..23028)
                     /gene="purB"
                     /locus_tag="RN951_002799"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HDX2527775.1"
                     /translation="MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWL
                     QKLAAHAAIKEVPAFAADAIGYLDAIVASFSEEDAARIKTIERTTNHDVKAVEYFLKE
                     KVAEIPELHAVSEFIHFACTSEDINNLSHALMLKTARDEVILPYWRQLIDGIKDLAVQ
                     YRDIPLLSRTHGQPATPSTIGKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHI
                     AAYPEVDWHQFSEEFVTSLGIQWNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVW
                     GYIALNHFKQKTIAGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQ
                     RDLTDSTVLRNLGVGIGYALIAYQSTLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTV
                     MRRYGIEKPYEKLKELTRGKRVDAEGMKQFIDGLALPEEEKARLKAMTPANYIGRAIT
                     MVDELK"
     gene            complement(23032..23673)
                     /gene="hflD"
                     /locus_tag="RN951_002800"
     CDS             complement(23032..23673)
                     /gene="hflD"
                     /locus_tag="RN951_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high frequency lysogenization protein HflD"
                     /protein_id="HDX2527776.1"
                     /translation="MAKNYYDITLALAGICQSARLVQQLAHQGHCDADALHVSLNSII
                     DMNPSSTLAVFGGSEANLRVGLETLLGVLNASSRQGLNAELTRYTLSLMVLERKLSSA
                     KGALDTLGNRINGLQRQLEHFDLQSETLMSAMAAIYVDVISPLGPRIQVTGSPAVLQS
                     PQVQAKVRATLLAGIRAAVLWHQVGGGRLQLMFSRNRLTTQAKQILAHLTPEL"
     gene            complement(23709..24815)
                     /gene="mnmA"
                     /locus_tag="RN951_002801"
     CDS             complement(23709..24815)
                     /gene="mnmA"
                     /locus_tag="RN951_002801"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415651.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HDX2527777.1"
                     /translation="MSETAKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDD
                     GEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILC
                     NKEIKFKAFLEFAAEDLGADYIATGHYVRRADVDGKSRLLRGLDSNKDQSYFLYTLSH
                     EQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFREFLGRYLPAQP
                     GKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKEGTEEPWYVVDKDVENNILVVAQG
                     HEHPRLMSVGLIAQQLHWVDREPFTGTMRCTVKTRYRQTDIPCTVKALDDDRIEVIFD
                     EPVAAVTPGQSAVFYNGEVCLGGGIIEQRLPLPV"
     gene            complement(24869..25330)
                     /gene="nudJ"
                     /locus_tag="RN951_002802"
     CDS             complement(24869..25330)
                     /gene="nudJ"
                     /locus_tag="RN951_002802"
                     /EC_number="3.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase NudJ"
                     /protein_id="HDX2527778.1"
                     /translation="MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETL
                     VEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDID
                     CCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTKGVI"
     gene            complement(25340..25993)
                     /gene="rluE"
                     /locus_tag="RN951_002803"
     CDS             complement(25340..25993)
                     /gene="rluE"
                     /locus_tag="RN951_002803"
                     /EC_number="5.4.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415653.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2457) synthase RluE"
                     /protein_id="HDX2527779.1"
                     /translation="MRQFIISENTMQKTSFRNHQVKRFSSQRSTRRKPENQPTRVILF
                     NKPYDVLPQFTDEAGRKTLKEFIPVQGVYAAGRLDRDSEGLLVLTNNGALQARLTQPG
                     KCTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGAELVDEPAWLWPRNPPIRER
                     KSIPTSWLKITLYEGRNRQVRRMTAHVGFPTLRLIRYAMGDYSLDNLANGEWREVTD"
     gene            26165..27415
                     /gene="icd"
                     /locus_tag="RN951_002804"
     CDS             26165..27415
                     /gene="icd"
                     /locus_tag="RN951_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="HDX2527780.1"
                     /translation="MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPA
                     MLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGP
                     LTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIY
                     AGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAI
                     ANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIV
                     IKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANIGDECAL
                     FEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAINAKTVTYD
                     FERLMEGAKLLKCSEFGEAIIENM"
BASE COUNT         6702 a         6941 c         7132 g         6710 t
ORIGIN      
        1 attaatgatt gttataaaaa atatcttgta tgtgatccag atcacatcta tcatttagtt
       61 atcgatcgtt aagtaattgc ttgcgacgtc attcatctgc ataaggccac tattatgaaa
      121 aacgtaaaaa ccctcatcgc tgcggcgatt ttaagctcca tgtcatttgc cagctttgcg
      181 gctgtcgaag ttcagtcaac gccagaaggc caacaaaaag tcggtacaat cagtgctaac
      241 gcggggacaa atctgggatc gctggaagag cagctggcgc aaaaagcgga tgagatgggc
      301 gcaaaatctt tccgtattac ttctgtaacc ggtccgaata ccctccatgg aacagcagta
      361 atttataaat aagcattaac cctcattaat gcctgctact gctgattttt tccccgcgac
      421 atgccgtgtc gcggggattt ttttatccgg gctttacagc gtttgtgggc tcacttgatg
      481 acggcggaca tccaccggca tcccggaacg gacatccatc acatgttgca tcacttcagc
      541 gtcagtttgt gctgcatctt taaatgattg cattgcgcta ttcagcgtaa ttggcagcag
      601 ctgcggatcg tcatcaatct tctctgacag cggctgatgt acttcaacca gacgcgcacc
      661 gtttggttcg gcagagactt ttatcggagt gttgatgata ttcactttgg tgcctggggt
      721 gacctggcta aagagtgttt tgatatcgtc atcccgcaga cgaatacagc cagaacttac
      781 ccgcatgcca atgccgaaat cggcgttcgt accatgaagc aaataaacgc cgccataggc
      841 cgccagacga atcgcatgat ggcccattgg gttatccggt ccagccggca ctaccgcagg
      901 caactcaatt ccctgtgctt tataacgggc gcggatgttt gccgttggcg tccaggttgg
      961 gtttgcacgt ttgtctgaaa cggtggtcac cattgtcggt gtcagcgtgt caccacctaa
     1021 ctgaccaata cctattggat acacggttac cgaattttta cccggcgggt agtaatagag
     1081 acgcagctcc gcaatgttga tcacaatgcc ttcgcgcggc gcatctggaa gtagggtttg
     1141 caacgggatc gttaacacgc tgcccgcgcg cggtacgtaa ggatcaacgc cggggttagc
     1201 ctgtaacaga gcgagaaagc cgacgttgta ttttttggcg atggcttcca gagaaccacc
     1261 gtcattttcc accacatgaa atttgttttc gccaaccaga cgactgcccg ctggcggcag
     1321 cggccaggtg ttggcttttg ccggtagcgc cagcgccacg gcagcggcga acgtaaaaaa
     1381 cgttagccag cgagaaaaac gcgttttgat catcaccaaa aatccataat aaatataagg
     1441 ttattgtaat aaacagataa gcctgaatta tggatggtga cagtgtcgga tagtgcaggg
     1501 aagtgcaaag aatttgtaaa tgttgcagat gggggcgcag aaacgccccc gatttaccat
     1561 taagcgatcg cgttctcttc cagttcacgc ataaactggc gtacccattc gatacgcgtt
     1621 ttccgctcac tcaaatcctg aataaatttc aggcgcgtcg gaccatcaag gcggtaatgc
     1681 tgcggctgtt tttgcagcaa accaatcaac ctggccggat taacgtgatt cttctcggca
     1741 aattcgatca ccccgccttt ctcattacct tccagcttcc tgatccccag tttctgcgct
     1801 tgctggcgca gacgggcaat atccagcagg gtacgcgccg gatctggcag caggccgaag
     1861 cgatcgataa gctcgacttt gatctcttcc agttcgtttt ccgttttggc gctggcaata
     1921 cgtttgtaga acgacagacg cgtgttcacg tcagggatga aatcatctgg caatagcgac
     1981 ggcatccgca gctcgacttc tgtttgctgg ctggtgagat cttccagcga cggctcgcgt
     2041 ccggctttca gtgcatcgac ggcgttttcc agcaactcca tatacagcga gaaaccgatg
     2101 gtttccattg agccgctttg ttcttcgcca agcagttcac ccgcgccgcg aatctccaga
     2161 tcgtgcgttg ccagcgcaaa acctgccccg agatcttcca gcgaggcaat tgcttcaaga
     2221 cgtttttgtg catcggtagt catcgctttt ggatgcggtg tcagcaacca tgcatatgcc
     2281 tgatgatgcg aacgtccgac gcgaccgcgt aactggtgca gctgcgccag accgaagtga
     2341 tccgcgcgtt caatgataat agtgttggct gtcgggatgt cgatcccggt ttcgataatg
     2401 gttgtacaaa ccagcacgtt gaaacgttga tgatggaaat cattcatcac ccgttccagt
     2461 tcgcgctcgc gcatctgccc gtgaccgatg gcgatccgcg cttctggcac cagttctgcc
     2521 agccgttcgg cggctttctg aatgttttcc acatcattgt agagataata aacctgtcct
     2581 ccgcgcaaaa tttcacgcag gatcgcctcc cggaccacca tgctgtcata ctcacggaca
     2641 aaggttttaa ctgccagacg acgggcgggc ggcgtggcga taatcgacag gtcacgcatt
     2701 ccgctcattg ccatattcag cgtacgtggg atcggcgttg cagtaagcgt cagaatatcc
     2761 acgttcgcgc gcatcgcttt aatgcgctct ttatgacgca ccccgaagcg gtgttcttca
     2821 tcgacaatca gcaggcctaa atctttaaac ttgacgtcac tttgcagcag tttgtgcgta
     2881 ccgatcagaa tatcgatttt cccttccgcc acttccgcaa ggatttgcgt ctgctctttg
     2941 gcgctgcgga aacgggagat catttcgata cgtaccggcc agttggcgaa acggtcgcgg
     3001 aagttgtcgt aatgctgctg cgcgagaagg gtggtaggca ccagcaccgc cacctgcttg
     3061 tggttatcta ctgccaggaa agctgcgcgc atcgccactt ctgttttacc aaagccaaca
     3121 tcgccgcaca ccagacgatc cattgccagc ggctgacaca tgtcgctaag taccgcatta
     3181 atggcctgcg cctgatccgg cgtggtttca aacgggaagc tgtcgcagaa caactgatac
     3241 tgctcacgat cgtgtttaaa cgcgaagccc tctttggcgg cgcgttgcgc gtaaatatcc
     3301 agcaattccg ccgccacatc acgcactttt tccgccgctt tctgccgcgc gcgtgaccac
     3361 gcatcgccgc caagtttatg cagcggggcg ttttcttccg cgccacctgc gtaacggcta
     3421 atcagatgca gtgacgacac cggaacatac agtttggcgt cgttggcata ggtgagcatc
     3481 agatactcgc cagtaatgcc acccgcttcc agcgtggtca ttccggcata acgaccgacg
     3541 ccgtgctcca gatggaccac cggctgacca atatgcagtt ccgcaaggtt acggatcagt
     3601 gtatcggggt tgatggtgcg gcgagaatcc tgacgacgac gggcaacgcg ttcaccgagc
     3661 agatcgcttt cgcaaatcag cgccagatta cgcaccgtat cgacaaaacc atgttcggca
     3721 gcgccaatca tcagataacg cccacggtcg ctggcttcat caagacgcat aatgcgttgc
     3781 ggagcaattt taattcgtgc gagcagttca cccagcgctt cacggcgacc ttcactttct
     3841 accgagaaca ccaccggacc gtcgaaagtc tcgaggaact tacgcagcgc atccagcggc
     3901 gctttttgtt gtgcctgaac ggccaggtct ggcagtttct ggaaacctaa attggcattc
     3961 gcggcttttg tcggtaaatg ttcagttttt agctgcaccc ggggccagtt tttcagctct
     4021 gagaagagct cgtccacccg cagccagagc gattgtggtg gcaacagcgg gcgcatcgga
     4081 tcgacgccgc gattctcaaa acgcgccagc gtgtcagcct ggaaacgttc ggcactggtt
     4141 tccagatcgc cagtattcac gagcaaggta ttggcaggga aataactgaa cagcggcggc
     4201 agtggttcgc tgaagaacaa tggctgccag tactcgatcc cggcaggtaa tgtgccttta
     4261 ctcacttgct ggtaaatatg ttctggatcg cgcttcactt cgaaggtatc gcgccactgg
     4321 ctgcggaaca gttcaattgc cgctttatcg gtcggaaatt cgtgcgcggg cagcagattg
     4381 atcgcttcta cttcctccag cgtgcgctgg ctgtcgacgt caaacacccg caggctgtcg
     4441 atttcatcat caaagaaatc aagacgataa ggcagctcac tccccatcgg gaagagatcc
     4501 agcaacgcgc cgcgcgtggc gtattcgccg tgctccatca cctggtcaac atggcgataa
     4561 ccggcgctgt ccagttgggt tcgtaatgca tctcgtgaca ggcgctgacc ttttttcatc
     4621 accagcgcat gaccgtggag aaaactgtgt gggcaaacgc gctgcataag cgtattcacc
     4681 ggaacaatca gtacgccacg ctgcatcgtc ggtagctggt aaagggtgga aaggcgcgag
     4741 gagataatgt cctgatgagg cgaaaaactg tcgtagggaa gagtttccca gtccgccaga
     4801 ttcatcacca tttgatcggt aaactggctg atttcatcat gcaaacgcag agcattttgc
     4861 atatctggtg caatgagtac caccggaccg gcgtgacgtt cggcaatttc cgctaccagc
     4921 gttgcacagg ctgcgccggt taactcgccc agcagacgct gctcacccgc tttgacgggc
     4981 agcgtataac gatattgttc aggcataacg gttgtcagat tctcgttagg atatgcctca
     5041 acatatgggg gcatatctct gataagcaat gctgttcatt atccgtaatc gacatggttt
     5101 agcaaattga atcgccccgg ctggggcgat ggcttagcgg gagtaactga cggcagcggg
     5161 cagtgaaggc ggggagaaca acagatcgct gaatgcacgc tgtgaaagtt ttcttaccag
     5221 caagcccgca acagtacaga tgaacaaact gacaaaggga taaaccagca ggagtgtcag
     5281 ttcgacttgc ggcgaccagc gtgctgcgtt catttgcgca agcagagtta agctgaatat
     5341 ttcaaccaga atgcgatggg tggtgtagat agcaatggtg ttggagccaa tcacattcag
     5401 caggctggtg gagcgcatac cgaatcgttg ctcgtattga taaaacagct tcatgatcac
     5461 cacaatcgat accagcgaca acagcagcga gatagtaaac aaccaggcac cgaccgccag
     5521 aacggtaagc aaagaagcca tcagcagatg gcggcgcaac ggcacctctt taacacaggt
     5581 cattattgtt gcgccaaacc atgcgccaag gctgtaataa ggcaaattgc ggatcacact
     5641 gttcattccc caccacggcg tgggaacgaa attaaccgcc acactcagca gtacaaacaa
     5701 ggcgaatagt ggcagcgcca gacggctaaa aattttacat accacgaaat agacaattaa
     5761 cgcatacaga taccacaagc tgttgctggc ggtgatcatc ccgtgcagga actcaccggt
     5821 ggaatcggca taagcggcat tggaggcatt gcttaaatcg cgctcaggtg ccagccactg
     5881 gttcagcgca cttaacgcca gccactgcac cacgccccaa agcgccagca cccagaagat
     5941 gttccagatc cgtttatcga gacaatttcc ccacggtacg ctgtcgatat agcggcgaat
     6001 caaatagccg gatataaaga aaaaaaccgg catacgaaag ggggcaaggt aaagattgaa
     6061 atagatccag catttgctca ggacttccga taacggatgc tgaaaagtgg tcagatgcgg
     6121 ataaaaggta atgaccgagt gataaatcac caccagacaa atacataacc ctttgatctg
     6181 gttaatccat agctcttttt gtttcatcag gacaacacgc tcttttttaa tttacatgcg
     6241 gttgatcctg cgggttatga cccgaggtgt aatgggtatc tgtctgtatt ggatgatttt
     6301 tcagattaag atcaggcggc aagattgatg ataaaacatg gcaatttagc cgattgattt
     6361 acgggggctt ttcagattag ccctgacgat cacttacagt tcagacgttt acccatcttg
     6421 ctttcgctta tatactcgtg tctttgctac agcaaccaga cggatttcat gtaccaacct
     6481 gtcgctctat ttattggcct gcgttacatg cgtgggcgtg cagcggatcg cttcggtcgt
     6541 ttcgtctcct ggctttctac catcggcatt accctcgggg tgatggcgct ggtcacagta
     6601 ttgtcagtga tgaacggctt tgagcgcgag ctgcaaaaca acatccttgg cctgatgcca
     6661 caggcaattc tctcttctga gcatggctct cttaacccgc agcaactccc agaaacggca
     6721 gtcaaactgg acggcgttaa tcgcgtcgca cctattacta ccggtgatgt ggtactgcaa
     6781 agcgcgcgca gcgtggcggt cggggtgatg ctcggtatcg acccggcgca aaaagatcca
     6841 cttacaccgt atctggtcaa tgtgaaacaa actgacctcg agccggggaa atataatgtc
     6901 atcctcggcg aacaacttgc ctcacagcta ggcgttaatc gcggtgatca aatccgcgtg
     6961 atggtaccat ctgccagcca gttcacgccg atggggcgta ttccaagcca gcgcctgttc
     7021 aatgtgattg gcactttcgc cgccaacagt gaagtcgatg gctatgaaat gctggtgaat
     7081 attgaggatg cctcgcgtct gatgcgttat ccggcaggca atattaccgg ctggcgtttg
     7141 tggctggatg agccgctgaa agtcgactca ttaagtcagc aaaaactgcc tgaaggcagc
     7201 aaatggcagg actggcgtga tcgtaaaggc gagttgttcc aggccgtacg catggaaaaa
     7261 aatatgatgg gtttactgct gagcctgatt gtcgccgttg cggcgtttaa cattattacc
     7321 tcactagggc tgatggtaat ggagaagcag ggcgaagtag cgatcctgca aacgcaaggc
     7381 ttaactccgc gacaaatcat gatggtcttt atggtgcaag gggccagcgc cgggattatc
     7441 ggtgcgatcc tcggagcggc gcttggcgcc ctgcttgcca gccagttaaa taatctgatg
     7501 ccgataatcg gcgtcctgct tgatggcgcg gcgctgccgg tggctatcga acctttacag
     7561 gtcattgtta ttgcgctggt ggcgatggct atcgcgctgc tgtctacgct ttacccttca
     7621 tggcgcgctg ccgccactca acccgctgag gctttacgtt atgaataaga tcctgttgca
     7681 atgcgacaac ctgtgcaaac gctatcagga aggcagtgtg caaaccgatg tgctgcacaa
     7741 tgtcagtttc agcgtcggcg aaggtgaaat gatggcgatc gtcggtagct ctggttccgg
     7801 taaaagtacc ttgctgcacc tgctgggcgg gctggatacg ccaacctccg gcgatgtgat
     7861 ttttaatggt cagccaatga gcaaactgtc gtcggcagcg aaagctgaac tgcgcaacca
     7921 gaagctgggc tttatttatc agtttcacca cctgctgccg gattttaccg ccctggaaaa
     7981 cgtggctatg ccgctgctga ttggcaagaa aaagcccgct gaaatcaaca gccgtgcact
     8041 tgagatgtta aaagcggtgg ggctggatca tcgtgcgaat caccgcccat ctgaactttc
     8101 tggcggcgaa cgccagcgtg tggcgattgc ccgtgcgctg gtgaataacc cgcgcctggt
     8161 actggcggat gaacctaccg gtaacctcga tgcgcgtaac gccgacagca tcttccagtt
     8221 gcttggggaa ttgaatcgct tgcagggcac cgccttcttg gtggttactc acgacctgca
     8281 actggcgaaa cgtatgagcc gccagttaga aatgcgtgat ggtcgtctga cggcggaact
     8341 gagcctgatg ggggcggagt aatggcgatg cctttatcgt tattaattgg cctgcgtttt
     8401 agtcgcggac ggcggcgcgg cggcatggtg tcgctgatct ccgttatttc taccattggc
     8461 attgccctcg gcgtggcggt attgatcgtc ggcttaagcg cgatgaacgg ctttgaacgc
     8521 gaactgaaca accgtattct ggcggtggtg ccgcatggtg aaatcgaggc ggtggatcag
     8581 ccgtggacta actggcagga agcactggat cacgtgcaaa aagtgccggg tattgccgct
     8641 gccgcgccgt atatcaattt caccgggctg gtggaaagtg gcgcgaatct tcgcgcaatc
     8701 caggtgaagg gcgttaaccc gcaacaggaa cagcgtctga gcgcattacc ctcgtttgtc
     8761 cagggcgatg cgtggcgcaa ttttaaagcg ggcgaacagc aaattatcat cggcaaaggc
     8821 gtggcggatg cgctgaaagt gaagcagggg gattgggtgt cgattatgat ccccaactcg
     8881 aatcccgagc ataaactgat gcagccaaaa cgtgtgcgtt tgcacgttgc cggtattttg
     8941 cagttgagtg gtcaactcga tcacagtttt gccatgatcc cgctggcgga tgcccaacaa
     9001 tatcttgata tgggttccag cgtgtcaggt attgccctta aaatgacgga tgttttcaac
     9061 gccaataagc tggtacgcga tgcgggtgaa gtgaccaaca gctatgttta tattaaaagc
     9121 tggattggta cttacggcta tatgtatcgc gatatccaaa tgatccgcgc cattatgtat
     9181 ctggcgatgg tactggtgat tggcgtggcc tgtttcaaca tcgtctccac cttagtgatg
     9241 gcggtgaaag acaagagtgg cgatatcgca gtattaagaa cgctgggggc gaaagatggt
     9301 ttaattcgcg ccatctttgt ctggtatgga ttgctggcag ggctgttcgg cagcctgtgt
     9361 ggtgtgatta tcggcgtagt ggtttcactg caacttaccc cgattattga gtggattgaa
     9421 aagttgatcg gtcatcagtt cctctccagc gatatctatt ttattgattt cctgccatcg
     9481 gaattgcact ggctggacgt cttctacgta ctggtcacag cattgttgct gagtcttttg
     9541 gcaagttggt atccggcgcg gcgcgccagt aatattgacc ctgcgcgagt ccttagcggc
     9601 cagtaaaggc agtacattaa aacaaggagc ggcaatgtat tacgggtttg atattggtgg
     9661 aacaaaaatt gcgcttggcg tgtttgatag cggtcggcag ttgcagtggg aaaagcgggt
     9721 gccgacaccg cgtgacagct atgacgcatt tttagatgca gtgtgtgagc tggtagctga
     9781 agctgaccaa cgttttggct gtaaaggttc tgtcggcatc ggtattccgg gaatgccgga
     9841 aacagaagat ggtacgctgt atgccgccaa tgtccccgct gccagcggta aaccgctgcg
     9901 tgccgacctg agcgcacgtc ttgatcgcga tgtacgcctt gataacgatg ccaactgttt
     9961 tgccctttca gaagcctggg atgatgaatt tactcaatat ccactggtga tggggttgat
    10021 tctcggcacc ggtgttggcg gcgggctgat tttcaacggc aaaccgatta ccggtaaaag
    10081 ctacattacc ggcgagtttg gccatatgcg tctgccggtt gatgcgttaa ccatgatggg
    10141 gttggatttc ccgttacgcc gctgcggctg tggtcagcat ggctgcattg aaaattatct
    10201 gtctggtcgc ggttttgcgt ggctgtatca acactattat catcaaccgt tgcaggctcc
    10261 cgaaattatt gcgctttatg atcaaggcga tgagcaggca agggcgcacg ttgagcgtta
    10321 tctggattta ttagcggttt gtctgggaaa tatcctgacc atcgttgacc ctgacctggt
    10381 cgtcattggt ggtggcttat cgaatttccc ggcaatcaca acgcaactgg cggacaggct
    10441 gcctcgtcat ctcttacctg tagctcgtgt tccgcgcatt gaacgcgcgc gccacggtga
    10501 tgcgggagga atgcgtggtg cggccttcct acatctaacc gattaaacaa cagaggttgc
    10561 tatgctgtcg cgtcggggtc atcggttaag tcgttttcgt aaaaataaac gccgcctgcg
    10621 cgagcgtttg cgtcagcgta tttttttcag agataaagtg gtgccggaag caatggaaaa
    10681 accaagagta ctcgtactga caggggcagg aatttctgcg gaatcaggta ttcgtacctt
    10741 tcgcgccgca gatggcctgt gggaagaaca tcgggttgaa gatgtggcaa cgccggaagg
    10801 tttcgatcgc gatcctgaac tggtgcaagc gttttataac gcccgtcgtc gacagctgca
    10861 gcagccagaa attcagccta acgccgcgca tcttgcgctg gctaaactgc aagacgccct
    10921 cggcgatcgc tttttgctgg tgacgcagaa tatcgacaac ctgcatgaac gcgcaggtaa
    10981 taccaatgtg attcatatgc atggggaact gctgaaagtg cgttgttcac aaagtggtca
    11041 ggttctcgac tggacaggag acgttacccc agaagataaa tgccattgtt gccagtttcc
    11101 ggcacccttg cgcccgcacg tagtgtggtt tggcgaaatg ccactcggca tggatgcaat
    11161 ttatatggcg ttgtcgatgg ccgatatttt cattgccatt ggcacatccg ggcatgttta
    11221 tccggcggct gggtttgttc acgaagcgaa actgcatggc gcgcacaccg tggaactgaa
    11281 tcttgaaccg agtcaggttg gtaatgaatt tgccgagaaa tattacggcc cggcaagcca
    11341 ggtggtgcct gagtttgttg aaaagttgct gaagggatta aaagcgggaa gcattgcctg
    11401 atgcactacg cttatcaggc ctgcaagggg acgcaattaa ttgaatttgc gggttttgtg
    11461 ggccggataa ggcgttcgcg ccccatccgg cataatacac gcgcactttt ccggcctctt
    11521 ttatcgttta ctcgtcaata acaatgcggc aataaacgta cagacaccaa ttagccctgc
    11581 ccagagtggc gatattctgg taatcgcaaa gctattatcg atatacaaac ataaagcctg
    11641 ataacccata ttggcaatag tcatcgccac tgcaaatttt aacgcataaa taaaacgagt
    11701 cgtgtagtaa aagatcctgg aaaataagat aaacgtcgca gcccaggcga taaaacctaa
    11761 tgtgttggtg ctgccggggg gagcattttc atgctgttgt cctggatgcg gataatacgt
    11821 tagtggcggc gtcgattgtt ttaatatctg tgcttgtaga acagccaatg cattattgat
    11881 tccctgatac cagagatctg catttaaata agccagcgtg tgattttcta tcagaaggcc
    11941 gagatgttta tcgtccagac cactttcaac ctggccgttg gtgatcataa ttaaccgtgg
    12001 ttcgcgggta gtaaatagta acagaacact tccttttaca tcactcaatg aagatgacgc
    12061 atgcgccagc atcgctttac cattttgtct gagactggct tcattattaa tgtcgggtaa
    12121 aaccacaata aacggtgcaa ttcccgtttg ttggcgaaaa agctcggctt tatgcgcgat
    12181 ctcttcagca tctggtacag taccggtaac gtccgtaaaa agtgtcttca ttattggaat
    12241 taatggcttg ctggctgctg tcagaggcag gagtatcagt aaactgagca gtataatgaa
    12301 ttttttcatg ggcgggactt ccgtttcctg cgtgattttt tagaggaggg catacttatt
    12361 aataaaccga cggcgataaa aataacgccc ataatgccga taaaccccca tttaaaaaaa
    12421 ttaacccacg ggttatttat ctcagccttt tcaggatgcc cgggagaata ataaacatta
    12481 actttatcgc cttcgctgtc ttcataaaaa tcgctgccga tactcgaatt gaaaattagc
    12541 gtgtaatctg gcgtcggtcg aaaggcaacg acgggatacc acgaaccatc tttacccgtg
    12601 cgatgagaat gactggagtg ccagacggta tcaacaatga cgccttcggt atgaatcgcg
    12661 tctttgctat aggtgaactg gttataaaag acaacaacag aaatgaggat cagtaccaga
    12721 ccgataccga ggaatatacg aaagaaaact ttactgtcct gactcattag ccacatcctt
    12781 gctaactaaa aaacgggcgg taataccacc gcccgcttgc tgaattaacg tcctgctttc
    12841 agcttctgat aatactcttc ataaatgctg ctggctgcgc caacgtcatt ctgccattcg
    12901 ccatttttaa tggtttcagc atccgggtag agtgttttat cgttcgccac ttctggactt
    12961 aacagcttac gcgccgcaag gtttggcgtt ggataaccga tagtttcagc aacctgtttt
    13021 gccacatccg ggcgcagcag gaagttgatc aatttcagcg cgccttcttt gtttttggca
    13081 tttgccggga tcgccaggct gtccatccag aaaatgccgc cttctttcgg ccacaccacg
    13141 tcaattggcg tacccgcctg gcgtgcaacg aaagcagaac cgttccagat catgccgagg
    13201 ttaacttcgc cttccatgta cgggttcgcc gggttatcgg agttaaaggc tgccacgttt
    13261 ggcatcagtt ttttcagctc gttatatgca gcttcaatct ctttcggatc ggtggtgtta
    13321 ccggagtagc ccagcttacg cagcgccatc tggaacactt cacgggcatc gtcggtcaac
    13381 agcaggctgc ctttgtactc tggcttccac agatcggccc agctggtgac agatttcgga
    13441 tccaccgcat caccgttaac accaatcgcc gtcgcacccc agatatacgg aatggagtag
    13501 tcgttattcg ggtcaaaagg cttgttgagc atgtctggat cgagattgct gaagtttgtt
    13561 aacttcgact tgtcgatctt ctggatcatc ccttctttac gcattttatc aacgtaatag
    13621 gttgaaggaa ccaccagatc ataggcaccg tctttgtatg ttttcagctt ggcgtacatg
    13681 gtttcgttcg actcgtaagt cgaatagata accttaatac cggtttcttt ggtgaactgt
    13741 tcaagcagtc ctggcggcac gtactcggtc cagttgtaga aatacagcgt gttgttgtca
    13801 tcggcgtgag cggcgctcat gcccagtgcc agagcacccg ccgcgagcag gtggcgtgac
    13861 cattttttca tttaacgtcc cctgtgttac ctttcgtttt atcacgagca ataagctggc
    13921 tggcaataac catcaccagc gacagcacca gtaatatggt tgccagcgcg ttaacttccg
    13981 gcgatacgcc gactttgacc atcgaataaa tttttaacgg cagaatttca taacttggtc
    14041 cggtgacgaa cgaagaaact accacatcgt ccatcgacag ggtaaagctt aacacccagc
    14101 ccgccgccac cgctggaatt gccagtggca gaatgatttt tcgcagaatg gtaaattcgc
    14161 tggcaccgag atctttcgcc gcttccagca ttcgcacgtc aaaacctttc aggcgcgaat
    14221 acaccgtcac caccacaaat ggcaggcaga aggtgatatg cgagaacagc agcgaccaga
    14281 agccaagctg aatacccagc agcataaaca gcaccagcag cgaaatcgcc atcacgatat
    14341 ctggtgacat catcaccaca aacagcattc cgctaacgaa cggcttacca cgaaagcgat
    14401 aacggtacag cgcaactgcc gtcagtgaac cgataagcgt agcaaacgtc gccgaaaaca
    14461 ccgccattgt tagtgaatgc tgcgctgcct gtaacaggct gtcgttgttc atcagcaggc
    14521 tataccattt ggtggtaaaa ccctgccagt tgatgccaaa gcgcgagctg ttaaaggagt
    14581 tcacaatcaa aataatgatt gggatataca ggtacgcgta gatagcggtc ataaaaccgc
    14641 cgcgaagcag tcgaccgatc attcgagttc caccttctta ttcagcaaac gagaagcgcg
    14701 ccagtaaacc agcaacatca ggcccattac gatagtcagc gtaatgctgg tagctgcacc
    14761 aaacggccag tcacgaatat taaggaactg gaccttgatg acgttaccga tcagcaggtt
    14821 tttcgcaccg cccatcaggt cggatacata gaacaggccc atcgctggca gcatcaccag
    14881 cagacatccg gcaataattc ccggcatcgt cagtggaata atgatacgga taaaagtctg
    14941 taacttgctg gcaccgagat cgcgcgccgc ctcaagcaac ggcttatcca gtttttcgat
    15001 actggagtac agcggcatca ccataaacgg cagcagaatg taaaccagac cgataatcac
    15061 cgcactgggc gtgaacatga tacggattgg tgtgtcgata acgcccagcc agagcaaaaa
    15121 ctcgttgaga tagcctttgg tgctgaggaa aattttcagc ccgtagatac gaattaatga
    15181 gttggtccag aacggaacaa tcagcagaaa cagcagcagc ggacgcacct tgtgtggcaa
    15241 cttcgccaga aaccaggcaa acgggtagcc cagcaccagg caggcgaggg tggcgatcag
    15301 cgccatattc agcgagtgca atagcacttc aaaatagagc ggatcgagca gacgcgtgta
    15361 gttatccagc gtaaagacca ttttgacaaa actggcgtcg tcgcgggtca aaaagctggt
    15421 gccaatgatc atcaggttgg gcagaaagac aaacaacaca agccaaccga caatagtgac
    15481 aatcactaca ttctggaact tacttgtgtt cttcatcagc cagtacgacc tcccagcttt
    15541 ctacccaatt aatggccatt ttttggtcga gagagtggtc aaagtcagga tcgtcttcat
    15601 tgaagaattc gctgaccatc accatcttgc cattttccag ttcaacaacc gactccagcg
    15661 tcatgccttt gtagttacgc tcgcgaacgt aaccaatcag cccttcagcg tggttgtcgt
    15721 cgttaatctc ttcaacacgt aagtcttccg ggcgcagcag aacatgcagt ttttgccccg
    15781 gttcaacggc gaagttaacg tagatattac attcgcggcc ttcaacgttg gcgcgtacgc
    15841 gctgctcgtc tagacgttcg atgacagtgg cgttaaacat attgatttcg ccaatgaagc
    15901 cggcaacaaa caggtttttc ggctcttcgt agatttcacg cggcgtgccg tcttgctcaa
    15961 tgcgaccatc gcgcatcacc acaatcctgt ctgacatggt gagtgcttct tcctggtcgt
    16021 gagtcacaaa gacgaatgta atgccaagct tacgctgtaa cgctttcagc tcgttctgca
    16081 tttgcttacg cagtttgtaa tccagcgctg agagcgactc atccagcaac aacagacgag
    16141 gcttgttaac caccgcgcga gcaatggcga cgcgttgctg ttgaccacca gagagctgat
    16201 gcggtttgcg ttgagcgaag gtttccaact gcaccatccg cagggcttcc atcacgcggg
    16261 gcgtaatttc agcagcgggg gttttttgca tgcgcaaccc aaaggccaca ttttcgaaca
    16321 cggtcatgtg ggggaaaagt gcgtagcttt ggaaaacagt gttcacatag cggttttccg
    16381 ccggaacgtg ggtgatgtcc tcgttatcca gcatgatgcg tccggaatca acagtttcca
    16441 gacctgcaat caggcgaaga acggttgttt taccgcagcc agaagggcca agcagcgtga
    16501 ggaactcgcc attgttgata gtcagatcca gctggggaat gacctcttta ccatcaaagc
    16561 atttgcgaat tcccgccaat tgcaccagcg gtgaaagcga actcggttgt ttattcaatt
    16621 ttttactctg tcccatgtaa acgcaacgga tggcttaccg atgcggggtt tgtggttaac
    16681 caccttggtg actcttaatg agggcggtaa ttctacggca aaccgcttga atcgccaatc
    16741 tttgttgtga attactggct tagctttata ttcattaagg taatgctgat aaatattccc
    16801 gcttgcaggg gtaaaagtga cctgacgcaa tatttgtctt ttcttgcttc ttaataatgt
    16861 tgtcacaaaa agtgagggtg actacatgga taaactactt gagcgatttt tgaactacgt
    16921 gtctctggat acccaatcaa aagcaggggt gagacaggtt cccagcacgg aaggccaatg
    16981 gaagttattg catctgctga aagagcagct cgaagagatg gggcttatca atgtgacctt
    17041 aagtgagaag ggcactttga tggcgacgtt accggctaac gtccctggcg atatcccggc
    17101 gattggcttt atttctcatg tggatacctc accggattgc agcggcaaaa atgtgaatcc
    17161 gcaaattgtt gaaaactatc gcggtggcga tattgcgctg ggtatcggcg atgaagtttt
    17221 atcaccggtt atgttcccgg tgctgcatca gctactgggt cagacgctga ttaccaccga
    17281 tggtaaaacc ttgttaggtg ccgatgacaa agcaggtatt gcagaaatca tgaccgcgct
    17341 ggcggtattg caacagaaaa aaattccgca tggtgatatt cgcgtcgcct ttaccccgga
    17401 tgaagaagtg ggcaaagggg cgaaacattt tgatgttgac gccttcgatg cccgctgggc
    17461 ttacactgtt gatggtggtg gcgtaggcga actggagttt gaaaacttca acgccgcgtc
    17521 ggtcaatatc aaaattgtcg gtaacaatgt tcatccgggc acggcgaaag gagtgatggt
    17581 aaatgcgctg tcgctggcgg cacgtattca tgcggaagtt ccggcggatg aaagcccgga
    17641 aatgacagaa ggctatgaag gtttctatca tctggcgagc atgaaaggca ccgttgaacg
    17701 ggccgatatg cactacatca tccgtgattt cgaccgtaaa cagtttgaag cgcgtaaacg
    17761 taaaatgatg gagatcgcca aaaaagtggg caaagggtta catcctgatt gctacattga
    17821 actggtgatt gaagacagtt actacaatat gcgcgagaaa gtggttgagc atccgcatat
    17881 tctcgatatc gcccagcagg cgatgcgcga ttgcgatatt gaaccggaac tgaaaccgat
    17941 ccgcggtggt accgacggcg cgcagttgtc gtttatggga ttaccgtgcc cgaacctgtt
    18001 cactggcggt tacaactatc atggtaagca tgagtttgtg actctggaag gtatggaaaa
    18061 agcggtgcag gtgatcgtcc gtattgccga gttaacggcg caacggaagt aagcgaaaag
    18121 ggatgcggca tgtgatgccg catccggctt aaatccaaac ttacccttcg aagaaccaat
    18181 acccgctatt gaccagcgcc gcgagcatcg cgaggaatga cggatcttcc agcgcatcgc
    18241 caaaattctc cgcagtcagc gcaatgttgc tggcgagtgc atccagtgcc ggacggtgcg
    18301 gggaatcgat cttctcacca ttggcataca cgtcgtcgcc aatgcgcaat acgcgcagac
    18361 cacccaggcg caccagcact tcaccttgtt tcagcgcatc gtagatttca tccggctgat
    18421 aaggcggctc tggcggcgcg atatccagtt catgacgtga ctgggatata aactcgccaa
    18481 accattgctt aaagtgttcc ggctggttga tcaattcgag catcatctca cgcagtttat
    18541 ccatctcttg cggcagaaca tccgcaggat gagcgcgagg tggaacatcc ggatcgctgt
    18601 agtagttgcc gcccagttca cgttgcagca cataatcggc aaatccacta atcagttccc
    18661 gcgtatttgg cgcgcgaaag cccacggaat agttcatcgc attttccagc gcgtagcctt
    18721 catgcgggaa tcctggcgga atataaagaa tatcaccagg ctccagctct tcatcgatga
    18781 tggcttcgaa cggatcgacc tgtaacagat ccggatgtgg gcagtgctgt ttcatttgca
    18841 gcttttcgcc cactcgccag cgacgacgtc cggtaccctg aatgataaac acgtcgtact
    18901 gatcgagatg cgggccgacg ccgccgccgg gtacagaaaa agaaatcatc agatcatcaa
    18961 tacgccagtc cggtagttca cggaacggtc gcatcagcgc ggcggtcggc tcatgccagt
    19021 ggttcactgc ctgtaccagt aatgaccagt tggtttcacc gagatgatcg tagctttcga
    19081 acgggccgtg gctgacctgc catttgccat cctggtgact gaccagtcga ctgtcaactt
    19141 cgctttccat cgccagaccc gccaactcgt ctggagagat cgggtcaata aaattattaa
    19201 agccgcgttt taacaccacc gggcgtttct gccagtgacg ttcaagaaaa tcgggccagt
    19261 taagagtgag ttggtattcc atgttaagca tccacaggct ggtatctgca accgattata
    19321 acggatgctt aacgtaatgc gtgaagtatg ggcatattta ttcatctttc ggcgcagaat
    19381 gctggcgacc aaaaatcacc tccatccgcg caccgcccag catgctctct ccggcgacga
    19441 ttttaccctc atattgctcg gtgatttcgc gggctaccgc cagccctaca ccttgcccag
    19501 ggcgtaaagt atcaacccgt tgaccacggt cgaaaatgac ctctcgcttg cttaatggaa
    19561 taccggggcc atcatcctcg accacaatat agagatgctc gtcggtttgc cttgcagaaa
    19621 tttcgacaaa ctcgaggcaa tatttacagg cattatccag cacgttgccc atcacctcga
    19681 caaaatcgtt ctgctcaccg acaaagctga tctctggcga aatatcgaga gagatattga
    19741 cccctttgcg ttgatacact ttgttcagcg ctgaggtgag attgtccagc agtggggcga
    19801 ccggatgcag ctcgcggctg agcaatgtcc cgccgcgcat actggcacga tgcaggtagt
    19861 agccaatttg ctgtgaaatg cggctgattt gctccagcat taccggctca gcatcactga
    19921 cgctcatctt ttcactacgc agagaacgca gcgtactttg cagcaccgcc agtggcgttt
    19981 tcagactatg ggtcaggtcg gtgagcgtcg tacggtattt gtcgtaacgt tcgcgttcac
    20041 tttttaacaa tcggttcagg tttcgtacca gactggtcag ttctcgcgtt gtggctggat
    20101 tgagcaattc gcggttatgt tcttccagtt cgcggacttc ttttgccagg gcttcgatgg
    20161 ggcgtaaact ccaccaggcg gcgacccaca gcagcgggat cactaacagc agattggctg
    20221 agagcacata gataaaccag ctccagacca tataggaact ttttagctcc accggaatgg
    20281 tatccaccac cacaatggtt aattttggca tccgcgatgt tgccgggtag acgtttactg
    20341 ccaccgagtg ggtcatctcc gcgtcgtcat catcttcccg cacttcctgc aactgttgct
    20401 gtatcgaatg atctccactc agcaagaggc tggtatcgtt aacatccgct tcaatttcat
    20461 gaaaaccatt cgatttcagc cagtcaggct ggatcatctt catcagccag ggcacgtcac
    20521 gttgcgccca taaaagctgc ccgttctcat cataaattag cgtcatggtg gggctttgct
    20581 tgtcgatatt ttcgggtaac tcgacatgca acttattgtt ttcccacttc gcaagggtat
    20641 agaacagatt gctctcgcca cgtaacagcc gaaacgtagt tttatcgaaa ctgacgctat
    20701 aaccgatcag cgcgaccatt ccgtaggcaa gcgaaagcac cagtactacc gctgccgttg
    20761 ccaacagaaa acgtacccgc agcgagagcg ggaaaaaaag acgcagtaat tttttcatca
    20821 gcgcaattcg aacagatagc cctggccgcg aacggtggta atcacttctt ggggatattg
    20881 tgcctgaatt tttttgcgca gacgtcccat cagtacatca atggtatggc tttcccgcag
    20941 ctccgcatcc ggatagagtt ggagcattaa cgaatctttg ctgaccactt tgccattatt
    21001 gcgtatcaac gtttccataa tggtgtattc gaacgcggtc agtttgatca cttcgtcatt
    21061 aatagataat tcacggcgag agagatcaac ctgaaacggg gggagcgaaa tgacctgtga
    21121 agccagaccg ctattacgcc gcattaatgc ctgcattcgc gccatcacct cttcaatatg
    21181 aaacggttta gtcacataat catcagcacc ggcacttaat acttcgactt tgtcctgcca
    21241 gctttcacgg gcggttaata ccagaatcgg cagtgaaaca tcgttgctac gccagcggcg
    21301 aatcagtgac agaccgtcct cgtctggcaa tccgagatcg acaatcgcaa tatccggtat
    21361 atgttcattg agataataat cggcttcttt ggcatcttct gcgtcatcga cctgatgacc
    21421 agcatcctga atctgaactt taaggtggtg acgtaacaac gcattgtctt caacaaccag
    21481 tacgcgcatt tttatttctc cctgtcttaa ttattaaaat agtgtaacgc gattatgtgg
    21541 ttatgggggt aaacattaaa taaaccagcg gggaggggag gtaaagtgaa aaaataaaaa
    21601 gcggataatc ttaataagca ggccggacag catcgccatc cggcactgat acgaggttta
    21661 tttcagctca tcaaccatcg tgatagctcg accaatatag ttagccggcg tcatcgcttt
    21721 caggcgggct ttctcttctt ctggcaacgc cagaccatcg ataaactgct tcatgccttc
    21781 ggcgtcaacg cgcttaccgc gagtcagctc tttcagcttc tcgtacggtt tttcgatgcc
    21841 atagcgacgc ataactgtct ggattggttc agccagcact tcccagttgt gatccagttc
    21901 atccagcaga tggtcacggt tcacttccag tttgctcacg cctttcaggg tggattgata
    21961 tgcaatcaag gcataaccga tacccacgcc gaggttacgc agcacggtag agtcggtcag
    22021 gtcacgctgc cagcgggaaa ccggcagttt gcttgccaga tgctgcaata ccgcgttgga
    22081 aaggcccaga ttcccttcgg agttttcgaa gtcgatcggg ttaactttat gcggcatggt
    22141 ggaagaacca atctcaccag caatggtttt ctgtttgaag tggttaaggg cgatataacc
    22201 ccagacgtca cggtcaaagt cgatcagaat agtgttgaag cgcgcaacgc aatcaaacag
    22261 ttcggcaatg tagtcgtgcg gttcgatctg ggtggtgtac gggttccact gaatacccag
    22321 cgaggtgacg aactcttcgc tgaactgatg ccagtcaact tccgggtaag cggcgatgtg
    22381 ggcgttatag ttaccgaccg cgccgttgat tttgccgagg atctccacct ggttaagctg
    22441 gcggtactgg cgctccatac ggtaggcgac gtttgccatc tctttaccga tggttgacgg
    22501 cgtggctggc tgaccgtggg tacgagacag cagcgggata tcgcgatact gaacggcgag
    22561 atctttaatg ccatcaatca gttgacgcca gtatggcagg atcacttcat cacgcgcggt
    22621 tttcagcatt aatgcgtggg agaggttatt gatatcttcc gaagtacagg caaagtggat
    22681 gaattcagaa accgcgtgca gttccgggat ctccgccact ttttctttca ggaaatactc
    22741 aaccgcttta acgtcgtggt tagtggtacg ctcgatagtt ttgatgcgcg ccgcatcttc
    22801 ttcgctgaaa ctggcgacga ttgcatcaag gtaaccgatt gcgtcggcag caaaagcagg
    22861 aacttccttg atcgctgcgt gcgcggccag tttttgcagc caacgtactt caacttgtac
    22921 acggaatttc agcaaaccat attcgctgaa aatcccgcgc agcgcgctga ctttatcgcc
    22981 gtagcgtcca tcgacagggg aaacggcggt cagtgaggat aattccatag atcacaactc
    23041 cggggttaaa tgagcaagaa tttgttttgc ctgagtggtc aggcgattac gagaaaacat
    23101 cagttgcaga cgtccgccgc cgacctggtg ccagagcacg gcggcgcgaa tgcctgccag
    23161 cagggttgcg cgaactttcg cctgcacttg tgggctttgc agtacagcag gggaaccggt
    23221 gacctgaatg cgcgggccaa gcgggctaat cacatcaaca tagatagcag ccatcgcgct
    23281 catcagcgtt tcggactgta aatcgaagtg ttcgagctgg cgttgcaggc cgttgatccg
    23341 gttgcccaga gtgtcgagcg cgcctttcgc tgaggagagt ttgcgctcaa gcaccatcaa
    23401 gctgagtgtg tagcgggtta attcggcgtt taagccctgg cgactgctgg cattgagcac
    23461 gccgagcagg gtttccagcc cgacgcgcag gttggcttcg ctaccgccaa aaaccgccag
    23521 cgtcgagctg gggttcatat caataatact gttgagtgag acgtgtagcg catcggcatc
    23581 acaatgcccc tggtgagcga gttgttgcac caggcgtgcc gactgacaaa taccggccag
    23641 ggcgagggtg atgtcatagt aattctttgc cacgttcact gcttccttgt tttaagtaaa
    23701 gataataatc agaccggcag cggcagacgc tgctcaataa taccgccacc gaggcacact
    23761 tcaccgttat agaagacggc agactggccc ggcgtcacgg cggcaaccgg ttcatcgaaa
    23821 atcacttcaa tgcgatcatc gtccagcgcc ttgacggtgc aagggatatc ggtctggcga
    23881 tagcgggttt ttaccgtgca acgcatagtg ccggtgaatg gttcgcgatc gacccagtgc
    23941 aactgctggg caatcaaccc gacagacatc agccgcgggt gttcatggcc ctgagcgaca
    24001 accagaatgt tgttttcgac gtctttgtcc accacatacc acggttcttc ggtaccttct
    24061 ttggtgccac cgatacccag acctttacgc tgaccgagag tgtgatacat cagcccctgg
    24121 tgctcaccaa tttcatcgcc atcgacggta atgattttgc ccggttgcgc cgggagataa
    24181 cggcccagga actcgcggaa tttacgttcg ccaatgaagc aaatgccggt agagtctttt
    24241 ttcttcgcgg tgaccagacc aagatcttca gcaatcttac gcacctgcgg tttttccagt
    24301 tcgccgaccg ggaacaggct ttgcgcaatc tgctcatggc tgagcgtata aaggaagtag
    24361 ctctggtctt tattgctgtc cagaccacgc agcaggcggc tcttgccatc gacatcggcc
    24421 cgacgtacgt aatgaccggt agcgatataa tcggcaccta aatcttcggc ggcaaattcg
    24481 aggaaggctt taaatttgat ctctttgttg cacagaatat ccggattcgg cgtgcgaccg
    24541 gctttatatt cggcaaggaa cagttcgaag acgttgtccc agtactcggc agcaaagtta
    24601 acggtgtgca gttcaatgcc gagcttgtcg cagacagcct gggcatcagc cagatccgct
    24661 gccgctgtgc aatattcctc accgtcgtct tcttcccagt tcttcataaa caggccttcg
    24721 acctgatatc cctgttgttg caacagccag gcagaaacgg aggaatcgac accgccggac
    24781 atgccgacga ttactttttt tgcggtttca gacattggat cactcacgac attgaacttc
    24841 aaggcggcgt attctatcac gcagcctttt agatgacacc ctttgtaaaa ggccagttaa
    24901 aatcgccaat catctccagc ggataacgtt gcccgctttg ataacaacga atactttccg
    24961 ccaccagcgg cgaacgaaga tttgacgcct gtaaaatttc ttcggcgctg acccaacggc
    25021 agcagtcgat atcgctgtca tgaggctggg tcgggcatat ttgctcaagc tcaatggcaa
    25081 agaggaaacg caaaaacggc gttttatctg gcgcaatcca ctgatgcata cgaataaagt
    25141 gttgcggctg cgcgctgatg ccggtttctt cccacagttc acgggcggcg gcttccacta
    25201 aggtttcatc ggcttccaga tgcccggcag gttggttcca taacgcttta ccattaatcg
    25261 tctcttcaac gactaaaaat ttgccttctg cgtgcaccac gcaagcaacg gtaacgtgcg
    25321 gtttaaacat tttgcatcct taatctgtca cttctcgcca ttcaccattg gcaagattat
    25381 ccaaagagta atcacccatc gcatagcgaa tcagtcgcag cgtggggaag ccaacatggg
    25441 cggtcatgcg gcgcacctgg cgattacgtc cttcatataa ggtgatcttc agccagctgg
    25501 tgggaatact tttgcgttca cgaattggtg gattccgcgg ccataaccac gcgggttcgt
    25561 caaccagctc cgcgccggcg ggcagggtag ggccatcatt taaggttacg ccattgcgca
    25621 aggcttcaag tgcgtcttgt gtgggaatac cttccacctg cacataatag atttttccgg
    25681 tgcatttacc cggctgggtt aaacgcgcct gcaacgcgcc gttattggtc agcaccagca
    25741 acccttcgct atcgcggtca aggcgacctg ctgcataaac accctgaacc gggatgaatt
    25801 cttttaatgt tttgcgtccg gcttcatcgg tgaactgcgg aagaacatcg tagggtttat
    25861 tgaacaggat cacacgcgtg ggctggtttt caggtttacg cctggtagaa cgttgcgagc
    25921 tgaatcgctt aacctggtga tttctaaaag aagttttttg catggtattt tcagagatta
    25981 tgaattgccg cattatagcc taataacgcg catctttcat gacggcaaac aatagggtag
    26041 tattgacaag ccaattacaa atcattaaca aaaaattgct ctaaagcatc cgtatcgcag
    26101 gacgcaaacg catatgcaac gtggtggcag acgagcaaac cagtagcgct cgaaggagag
    26161 gtgaatggaa agtaaagtag ttgttccggc acaaggcaag aagatcaccc tgcaaaacgg
    26221 caaactcaac gttcctgaaa atccgattat cccttacatt gaaggtgatg gaatcggtgt
    26281 agatgtaacc ccagccatgc tgaaagtggt cgacgctgca gtcgagaaag cctataaagg
    26341 cgagcgtaaa atctcctgga tggaaattta caccggtgaa aaatccacac aggtttatgg
    26401 tcaggacgtc tggctgcctg ctgaaactct tgatctgatt cgtgaatatc gcgttgccat
    26461 taaaggtccg ctgaccactc cggttggtgg cggtattcgc tctctgaacg ttgccctgcg
    26521 ccaggaactg gatctctaca tctgcctgcg tccggtacgt tactatcagg gcactccaag
    26581 cccggttaaa caccctgaac tgaccgatat ggttatcttc cgtgaaaact cggaagacat
    26641 ttatgcgggt atcgaatgga aagcagactc tgccgacgcc gagaaagtga ttaaattcct
    26701 gcgtgaagag atgggggtga agaaaattcg cttcccggaa cattgtggta tcggtattaa
    26761 gccgtgttcg gaagaaggca ccaaacgtct ggttcgtgca gcgatcgaat acgcaattgc
    26821 taacgatcgt gactctgtga ctctggtgca caaaggcaac atcatgaagt tcaccgaagg
    26881 agcgtttaaa gactggggct accagctggc gcgtgaagag tttggcggtg aactgatcga
    26941 cggtggcccg tggctgaaag ttaaaaaccc gaacactggc aaagagatcg tcattaaaga
    27001 cgtgattgct gatgcattcc tgcaacagat cctgctgcgt ccggctgaat atgatgttat
    27061 cgcctgtatg aacctgaacg gtgactacat ttctgacgcc ctggcagcgc aggttggcgg
    27121 tatcggtatc gcccctggtg caaacatcgg tgacgaatgc gccctgtttg aagccaccca
    27181 cggtactgcg ccgaaatatg ccggtcagga caaagtaaat cctggctcta ttattctctc
    27241 cgctgagatg atgctgcgcc atatgggttg gactgaagcg gctgacctga ttgttaaagg
    27301 tatggaaggc gcaatcaatg ccaagaccgt aacttatgac ttcgaacgtc tgatggaagg
    27361 cgctaagctg ctgaaatgtt cagagtttgg tgaagcgatc atcgaaaaca tgtaatctct
    27421 ccatgtgtta aatattgaaa cgggcgtata acacgcccgt tgttttattt atgtggatat
    27481 tatta
//
LOCUS       DAPOAV010000058        26670 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.058, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000058 DAPOAV010000000
VERSION     DAPOAV010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26670
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.058"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..348)
                     /locus_tag="RN951_002805"
     CDS             complement(<1..348)
                     /locus_tag="RN951_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527781.1"
                     /translation="METLFKVFEKFSSRPLFFIFFGLSLCEFFQKQSVLMNPSADNIA
                     KLFAAMILVVFFTWGFEWLIFKFNVNLEPHDQGDIGPTIGTATLAVYLVYAFHFLSEN
                     PEALNLKLLTNSGF"
     gene            complement(387..1616)
                     /locus_tag="RN951_002806"
     CDS             complement(387..1616)
                     /locus_tag="RN951_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001341819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDX2527782.1"
                     /translation="MAKIAKKLTDTEIKSTKPADKEINLFDGDGLILRIAPLAKGGKK
                     NWYFRYAVPVSKKRTKMSLGTYPHLTLARARALRDEYLSFLANGVDPQIHNNDKAKAL
                     KSATEHTLQAVARKWLDEKVKTSGISQDHAADIWRSLERNVFPGLGNVPINEIRPKLL
                     KQHLDPIEQRGVLETLRRIISRLNEIFRWAATEELIEFNPADNLGQRFSKPKKQNMPA
                     LPPSELPRFMESLTNASIRLETRMLIEWQLLTWVRPGEAVRARWSDIDTTNSIWNIPA
                     DFMKMKKLHKVPLSKEALRILELMKSISGHREWVFPSIKAPLNHMHEQTANAAIIRMG
                     FGGELVAHGMRSIARTAAEESGKFRAEVLEAALAHSKKDEIIAAYNRAEYLIERQSLM
                     QWWSDYVQAQRSNALVA"
     gene            complement(1782..2144)
                     /gene="ssrA"
                     /locus_tag="RN951_002807"
     tmRNA           complement(1782..2144)
                     /gene="ssrA"
                     /locus_tag="RN951_002807"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(2359..2841)
                     /gene="smpB"
                     /locus_tag="RN951_002808"
     CDS             complement(2359..2841)
                     /gene="smpB"
                     /locus_tag="RN951_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HDX2527783.1"
                     /translation="MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSL
                     RAGKANISDSYVLLRDGEAFLFGANITPMAVASTHVVCDPTRTRKLLLNQRELDSLYG
                     RVNREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDIKEREWQVDKARIMKNAHR
                     "
     gene            3012..3449
                     /gene="ratA"
                     /locus_tag="RN951_002809"
     CDS             3012..3449
                     /gene="ratA"
                     /locus_tag="RN951_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010376629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin RatA"
                     /protein_id="HDX2527784.1"
                     /translation="MPQISRTALVPYSAEQMYQLVNDVQSYPQFLPGCTGSRILESTP
                     GQMTAAVDVSKAGISKTFTTRNQLTSNQSILMNLVDGPFKKLIGGWKFTPLSQEACRI
                     EFHLDFEFTNKLIELAFGRVFKELASNMVQAFTVRAKEVYSAR"
     gene            3439..3729
                     /locus_tag="RN951_002810"
     CDS             3439..3729
                     /locus_tag="RN951_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417108.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfH family protein"
                     /protein_id="HDX2527785.1"
                     /translation="MPGKIAVEVAYALPEKQYLQRVTLQEGATVEEAIRASGLLELRT
                     DIDLTKNKVGIYSRPAKLSDSVHDGDRVEIYRPLIADPKELRRQRAEKSANK"
     gene            complement(3791..4132)
                     /gene="bamE"
                     /locus_tag="RN951_002811"
     CDS             complement(3791..4132)
                     /gene="bamE"
                     /locus_tag="RN951_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417107.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamE"
                     /protein_id="HDX2527786.1"
                     /translation="MRCKTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTANDVS
                     KIRVGMTQQQVAYALGTPLMSDPFGTNTWFYVFRQQPGHEGVTQQTLTLTFNSSGVLT
                     NIDNKPALSGN"
     gene            complement(4281..5942)
                     /gene="recN"
                     /locus_tag="RN951_002812"
     CDS             complement(4281..5942)
                     /gene="recN"
                     /locus_tag="RN951_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HDX2527787.1"
                     /translation="MLAQLTISNFAIVRELEIDFHSGMTVITGETGAGKSIAIDALGL
                     CLGGRAEADMVRTGAARADLCARFSLKDTPAALRWLEENQLEDGHECLLRRVISSDGR
                     SRGFINGTAVPLSQLRELGQLLIQIHGQHAHQLLTKPEHQKFLLDGYANETSLLQEMT
                     ARYQLWHQSCRDLAHHQQLSQERAARAELLQYQLKELNEFNPQPGEFEQIDEEYKRLA
                     NSGQLLTTSQNALALMADGEDANLQSQLYTAKQLVSELIGMDSKLSGVLDMLEEATIQ
                     IAEASDELRHYCDRLDLDPNRLFELEQRISKQISLARKHHVSPEALPQYYQSLLEEQQ
                     QLDDQADSQETLALAVTKHHQQALEIARALHQQRQQYAEELAQLITDSMHALSMPHGQ
                     FTIDVKFDEHHLGADGADRIEFRVTTNPGQPMQPIAKVASGGELSRIALAIQVITARK
                     METPALIFDEVDVGISGPTAAVVGKLLRQLGESTQVMCVTHLPQVAGCGHQHYFVSKE
                     TDGAMTETHMQSLNKKARLQELARLLGGSEVTRNTLANAKELLAA"
     gene            complement(6028..6906)
                     /gene="nadK"
                     /locus_tag="RN951_002813"
     CDS             complement(6028..6906)
                     /gene="nadK"
                     /locus_tag="RN951_002813"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) kinase"
                     /protein_id="HDX2527788.1"
                     /translation="MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCTKGYEVIVEQQIA
                     HELQLKNVKTGTLAEIGQLADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLT
                     DLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMI
                     EFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSA
                     RPLVINSSSTIRLRFSHRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYS
                     YFNTLSTKLGWSKKLF"
     gene            7029..7622
                     /gene="grpE"
                     /locus_tag="RN951_002814"
     CDS             7029..7622
                     /gene="grpE"
                     /locus_tag="RN951_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HDX2527789.1"
                     /translation="MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKI
                     ANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSL
                     DRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMV
                     ESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAKA"
     gene            complement(7677..8963)
                     /locus_tag="RN951_002815"
     CDS             complement(7677..8963)
                     /locus_tag="RN951_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026171.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDX2527790.1"
                     /translation="MEHISTTTLIIILIIMVVISAYFSGSETGMMTLNRYRLRHMAKQ
                     GNRSAKRVEKLLRKPDRLISLVLIGNNLVNILASALGTIVGMRLYGDAGVAIATGVLT
                     FVVLVFAEVLPKTIAALYPEKVAYPSSFLLAPLQILMMPLVWLLNAITRMLMRMMGIK
                     TDIVVSGSLSKEELRTIVHESRSQISRRNQDMLLSVLDLEKMTVDDIMVPRSEIIGID
                     INDDWKSILRQLSHSPHGRIVLYRDSLDDAISMLRVREAWRLMSEKKEFTKETMLRAA
                     DEIYFVPEGTPLSTQLVKFQRNKKKVGLVVNEYGDIQGLVTVEDILEEIVGDFTTSMS
                     PTLAEEVTPQNDGSVIIDGTANVREINKAFNWHLPEDDARTVNGVILEALEEIPVAGT
                     RVHIGEYDIDILDVQDNMIKQVKVFPVKPLRESVAE"
     gene            complement(8984..9775)
                     /locus_tag="RN951_002816"
     CDS             complement(8984..9775)
                     /locus_tag="RN951_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417102.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YpjD"
                     /protein_id="HDX2527791.1"
                     /translation="MPVFALLALVAYSVSLALIVPGLLQKNGGWRRMAIISAVIALVC
                     HAIALEARILPDGDSGQNLSLLNVGSLVSLMICTVMTIVASRNRGWLLLPIVYAFALI
                     NLALATFMPNEYITHLEATPGMLVHIGLSLFSYATLIIAALYALQLAWIDYQLKNKKL
                     AFNQEMPPLMSIERKMFHITQIGVVLLTLTLCTGLFYMHNLFSMENIDKAVLSIVAWF
                     VYIVLLWGHYHEGWRGRRVVWFNVAGAVILTLAYFGSRIVQQLIS"
     gene            9942..11303
                     /gene="ffh"
                     /locus_tag="RN951_002817"
     CDS             9942..11303
                     /gene="ffh"
                     /locus_tag="RN951_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HDX2527792.1"
                     /translation="MFDNLTDRLSRTLRNISGRGRLTEDNVKDTLREVRMALLEADVA
                     LPVVREFINRVKEKAVGHEVNKSLTPGQEFVKIVRNELVAAMGEENQTLNLAAQPPAV
                     VLMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAEQVGVDFF
                     PSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMDEIKQVHASINPVETL
                     FVVDAMTGQDAANTAKAFNEALPLTGVVLTKVDGDARGGAALSIRHITGKPIKFLGVG
                     EKTEALEPFHPDRIASRILGMGDVLSLIEDIESKVDRAQAEKLASKLKKGDGFDLNDF
                     LEQLRQMKNMGGMASLMGKLPGMGQIPDNVKSQMDDKVLVRMEAIINSMTMKERAKPE
                     IIKGSRKRRIAAGCGMQVQDVNRLLKQFDDMQRMMKKMKKGGMAKMMRSMKGMMPPGF
                     PGR"
     gene            11552..11800
                     /gene="rpsP"
                     /locus_tag="RN951_002818"
     CDS             11552..11800
                     /gene="rpsP"
                     /locus_tag="RN951_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HDX2527793.1"
                     /translation="MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIAS
                     EKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVNKAA"
     gene            11819..12367
                     /gene="rimM"
                     /locus_tag="RN951_002819"
     CDS             11819..12367
                     /gene="rimM"
                     /locus_tag="RN951_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HDX2527794.1"
                     /translation="MSKQLTAQAPVDPIVLGKMGSSYGIRGWLRVFSSTEDAESIFDY
                     QPWFIQKAGQWQQVQLESWKHHNQDMIIKLKGVDDRDAANLLTNCEIVVDSSQLPQLE
                     EGDYYWKDLMGCQVVTTEGYDLGKVVDMMETGSNDVLVIKANLKDAFGIKERLVPFLD
                     GQVIKKVDLTTRSIEVDWDPGF"
     gene            12398..13165
                     /gene="trmD"
                     /locus_tag="RN951_002820"
     CDS             12398..13165
                     /gene="trmD"
                     /locus_tag="RN951_002820"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HDX2527795.1"
                     /translation="MWIGIISLFPEMFRAITDYGVTGRAVKNGLLSIQSWSPRDFTHD
                     RHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSEL
                     ATNQKLILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVL
                     GHEASATEDSFAEGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWL
                     RRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA"
     gene            13207..13554
                     /gene="rplS"
                     /locus_tag="RN951_002821"
     CDS             13207..13554
                     /gene="rplS"
                     /locus_tag="RN951_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012768745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HDX2527796.1"
                     /translation="MSNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFE
                     GVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSISVKRRGAVRKAKLYYLRE
                     RTGKAARIKERLN"
     gene            complement(13631..14113)
                     /locus_tag="RN951_002822"
     CDS             complement(13631..14113)
                     /locus_tag="RN951_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDX2527797.1"
                     /translation="MIKHLVAPLIFTSLILTGCQSPQGKFTPEQVAAMQSYGFTESAG
                     DWSLGLSDAILFAKNDYKLLPESQQQIQTMAAKLASTGLTHARMDGHTDNYGEDSYNE
                     GLSLKRANVVADAWAMGGQIPRSNLTTQGLGKKYPIASNKTAQGRAENRRVAVVITTP
                     "
     gene            complement(14129..15355)
                     /gene="dgcN"
                     /locus_tag="RN951_002823"
     CDS             complement(14129..15355)
                     /gene="dgcN"
                     /locus_tag="RN951_002823"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcN"
                     /protein_id="HDX2527798.1"
                     /translation="MMDNDNSLNKRPTFKRALRNISMTSIFITMMLIWLLLSVTSVLT
                     LKQYAQKNLALTAATMTYSLEAAVVFADGPAATETLAALGQQGQFSTAEVRDKQQNIL
                     ASWHYTRKDPGDTFSNFISHWLFPAPIIQPIRHNGETIGEVRLTARDSSISHFIWFSL
                     AVLTGCILLASGIAITLTRHLHNGLVEALKNITDVVHDVRSNRNFSRRVSEERIAEFH
                     RFALDFNSLLDEMEEWQLRLQAKNAQLLRTALHDPLTGLANRAAFRSGINTLMNNSDA
                     RKTSALLFLDGDNFKYINDTWGHATGDRVLIEIAKRLAEFGGLRHKAYRLGGDEFAMV
                     LYDVQSESEVQQICSALTQIFNLPFDLHNGHQTTMTLSIGYAMTIEHASAEKLQELAD
                     HNMYQAKHQRAEKLVR"
     gene            complement(15345..15863)
                     /locus_tag="RN951_002824"
     CDS             complement(15345..15863)
                     /locus_tag="RN951_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiR family protein"
                     /protein_id="HDX2527799.1"
                     /translation="MRFSHRLFLLLILLLTGAPILAQEPSDVAKNVRMMVSGIVSYTR
                     WPALSGPPKLCIFSSSRFSTALQENAATSLPYLPVIIHTQQEAMISGCNGFYFGNESP
                     TFQMELTEQYPSKALLLIAEQNTECIIGSAFCLIIHNNDVRFAVNLDALSRSGVKVNP
                     DVLMLARKKNDG"
     gene            complement(16013..16378)
                     /locus_tag="RN951_002825"
     CDS             complement(16013..16378)
                     /locus_tag="RN951_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2799 domain-containing protein"
                     /protein_id="HDX2527800.1"
                     /translation="MMKKFIAPLLALLVSGCQIDPYTHAPTLTSTDWYDVGMEDAISG
                     SAIKDDDAFSDSQADRGLYLKGYAEGQKKTCQTDFTYARGLSGKSFPASCNNVENASQ
                     LHEVWQKGADENASTIRLN"
     gene            16588..17658
                     /gene="aroF"
                     /locus_tag="RN951_002826"
     CDS             16588..17658
                     /gene="aroF"
                     /locus_tag="RN951_002826"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroF"
                     /protein_id="HDX2527801.1"
                     /translation="MQKDALNNVHITDEQVLMTPEQLKAAFPLSLQQEAQIADSRRTI
                     SDIIAGRDPRLLVVCGPCSIHDPETALEYARRFKALAAEVSDSLYLVMRVYFEKPRTT
                     VGWKGLINDPHMDGSFDVEAGLQIARKLLLELVNMGLPLATEALDPNSPQYLGDLFSW
                     SAIGARTTESQTHREMASGLSMPVGFKNGTDGSLATAINAMRAAAQPHRFVGINQAGQ
                     VALLQTQGNPDGHVILRGGKAPNYSPADVAQCEKEMEQAGLRPSLMVDCSHGNSNKDY
                     RRQPAVAESVVAQIKDGNRSIIGLMIESNIHEGNQSSEQPRSEMKYGVSVTDACISWE
                     MTDALLREIHQDLNGQLTARVA"
     gene            17669..18790
                     /gene="tyrA"
                     /locus_tag="RN951_002827"
     CDS             17669..18790
                     /gene="tyrA"
                     /locus_tag="RN951_002827"
                     /EC_number="1.3.1.12"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydrogenase"
                     /protein_id="HDX2527802.1"
                     /translation="MVAELTALRDQIDEVDKALLNLLAKRLELVAEVGEVKSRFGLPI
                     YVPEREASMLASRRAEAEALGVPPDLIEDVLRRVMRESYSSENDKGFKTLCPSLRPVV
                     IVGGGGQMGRLFEKMLTLSGYQVRILEQHDWDRAADIVADAGMVIVSVPIHVTEQVIG
                     KLPPLPKDCILVDLASVKNGPLQAMLAAHDGPVLGLHPMFGPDSGSLAKQVVVWCDGR
                     KPEAYQWFLEQIQVWGARLHRISAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQ
                     LLALSSPIYRLELAMVGRLFAQDPQLYADIIMSSERNLALIKRYYKRFGEAIELLEQG
                     DKQAFIDSFRKVEHWFGDYAQRFQSESRVLLRQANDNRQ"
     gene            complement(18833..19993)
                     /gene="pheA"
                     /locus_tag="RN951_002828"
     CDS             complement(18833..19993)
                     /gene="pheA"
                     /locus_tag="RN951_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydratase"
                     /protein_id="HDX2527803.1"
                     /translation="MTSENPLLALREKISALDEKLLALLAERRELAVEVGKAKLLSHR
                     PVRDIDRERDLLERLITLGKAHHLDAHYITRLFQLIIEDSVLTQQALLQQHLNKINPH
                     SARIAFLGPKGSYSHLAARQYAARHFEQFIESGCAKFADIFNQVETGQADYAVVPIEN
                     TSSGAINDVYDLLQHTSLSIVGEMTLTIDHCLLVSGTTDLSTINTVYSHPQPFQQCSK
                     FLNRYPHWKIEYTESTSAAMEKVAQAKSPHVAALGSEAGGTLYGLQVLERIEANQQQN
                     FTRFVVLARKAINVSDQVPAKTTLLMATGQQAGALVEALLVLRNHNLIMTRLESRPIH
                     GNPWEEMFYLDIQANLESAEMQKALKELGEITRSMKVLGCYPSENVVPVDPT"
     misc_feature    complement(20015..20140)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01859"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Phe leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF01859"
     gene            complement(20092..20139)
                     /gene="pheL"
                     /locus_tag="RN951_002829"
     CDS             complement(20092..20139)
                     /gene="pheL"
                     /locus_tag="RN951_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pheA operon leader peptide PheL"
                     /protein_id="HDX2527804.1"
                     /translation="MKHTPFFFAFFFTFP"
     gene            complement(20243..20584)
                     /gene="raiA"
                     /locus_tag="RN951_002830"
     CDS             complement(20243..20584)
                     /gene="raiA"
                     /locus_tag="RN951_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDX2527805.1"
                     /translation="MTMNITSKQMEITPAIRQHVADRLAKLEKWQTHLINPHIILSKE
                     PQGFVADATINTPNGVLVASGKHEDMYTAINELINKLERQLNKLQHKGEARRAATSVK
                     DANFVEEVEEE"
     gene            complement(20855..21592)
                     /gene="bamD"
                     /locus_tag="RN951_002831"
     CDS             complement(20855..21592)
                     /gene="bamD"
                     /locus_tag="RN951_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamD"
                     /protein_id="HDX2527806.1"
                     /translation="MTRMKYLVAAATLSLFLAGCSGSKEEVPDNPPNEIYATAQQKLQ
                     DGNWRQAITQLEALDNRYPFGPYSQQVQLDLIYAYYKNADLPLAQAAIDRFIRLNPTH
                     PNIDYVMYMRGLTNMALDDSALQGFFGVDRSDRDPQHARAAFSDFSKLVRGYPNSQYT
                     TDATKRLVFLKDRLAKYEYSVAEYYTERGAWVAVVNRVEGMLRDYPDTQATRDALPLM
                     ENAYRQMQMNAQAEKVAKIIAANSSNT"
     gene            21727..22707
                     /gene="rluD"
                     /locus_tag="RN951_002832"
     CDS             21727..22707
                     /gene="rluD"
                     /locus_tag="RN951_002832"
                     /EC_number="5.4.99.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017383977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(1911/1915/1917) synthase
                     RluD"
                     /protein_id="HDX2527807.1"
                     /translation="MAQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWILDQR
                     VLVNGKVCDKPKEKVLGGEQVAINAEIEEEARFEPQDIPLDIVYEDEDIIVINKPRDL
                     VVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVE
                     SLQRREITREYEAVAIGHMTAGGTVDEPISRHPTKRTHMAVHPMGKPAVTHYRIMEHF
                     RVHTRLRLRLETGRTHQIRVHMAHITHPLVGDPVYGGRPRPPKGASEAFISMLRKFDR
                     QALHATMLRLYHPISGIEMEWHAPIPQDMVELIEVMRADFEEHKDEVDWL"
     gene            22704..23435
                     /gene="pgeF"
                     /locus_tag="RN951_002833"
     CDS             22704..23435
                     /gene="pgeF"
                     /locus_tag="RN951_002833"
                     /EC_number="1.10.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphenol oxidase"
                     /protein_id="HDX2527808.1"
                     /translation="MSKLIVPQWPLPKGVAACSSSRIGGVSLPPYDSLNLGAHCGDNP
                     DHVEENRKRLFAAGNLPSKPVWLEQVHGKDVLKLTGEPYASKRADASYSNTPGTVCAV
                     MTADCLPVLFCNRAGTEVAAAHAGWRGLCAGVLEETVSCFADNPENILAWLGPAIGPR
                     AFEVGVEVREAFMAVDAKASAAFIQHGDKYLADIYQLARQRLANVGVEQIFGGDRCTY
                     TENETFFSYRRDKTTGRMASFIWLI"
     gene            23565..26138
                     /gene="clpB"
                     /locus_tag="RN951_002834"
     CDS             23565..26138
                     /gene="clpB"
                     /locus_tag="RN951_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002461515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HDX2527809.1"
                     /translation="MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGG
                     SVSPLLTSAGINAGQLRTDINQALNRLPQVEGTGGDVQPSQDLVRVLNLCDKLAQKRG
                     DNFISSELFVLAALESRGTLADILKAAGATTANITQAIEQMRGGESVNDQGAEDQRQA
                     LKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEG
                     LAQRIINGEVPEGLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILF
                     IDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYRQYIEKDAALERRFQ
                     KVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAID
                     LIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELSD
                     KERQYSELEEEWKAEKASLSGTQTIKAELEQAKIAIEQARRVGDLARMSELQYGKIPE
                     LEKQLEAATQLEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMMESEREKLLRMEQEL
                     HHRVIGQNEAVDAVSNAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKALANFMFD
                     SDEAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKA
                     HPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQERFGELDYAHMKEL
                     VLGVVSHNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLKRLYKRLEERGYEIHISDE
                     ALKLLSENGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEVNEDRIVAV
                     Q"
     gene            26582..>26670
                     /locus_tag="RN951_002835"
     rRNA            26582..>26670
                     /locus_tag="RN951_002835"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT         6619 a         6248 c         6953 g         6850 t
ORIGIN      
        1 aaagccagag ttagttaata actttaaatt taatgcttca ggattttcac tgagaaagtg
       61 aaaggcataa actaagtata cagctaaagt agccgttcca attgttggtc caatatcgcc
      121 ttgatcatga ggttcaaggt ttacattgaa cttgaagatt agccattcaa atccccaagt
      181 aaaaaaaaca actaatatca tggctgcgaa taatttcgcg atgttatctg ctgatggatt
      241 catcagaaca gattgtttct gaaaaaattc acaaagtgag agtccgaaaa aaataaaaaa
      301 aagtggtctg gaactaaatt tttcaaaaac tttgaatagg gtttccattt tctttacctt
      361 caggattata ttagctattc tgatacttag gctaccagag catttgatct ttgagcttga
      421 acgtaatcac tccaccattg catcaaactc tgtcgctcta tcagatattc tgcacgattg
      481 tatgctgcga taatttcatc ttttttcgag tgggcaagcg ctgcctcaag aacttcagct
      541 ctgaatttac cagactcctc tgccgctgtt cgtgcaatag aacgcatacc gtgagctaca
      601 agctcgcctc cgaaccccat tcggatgata gctgcgttgg ctgtttgttc atgcatatga
      661 ttaagaggcg cttttatgct ggggaaaacc cattctctat gcccacttat tgatttcatt
      721 aattcaagga tgcgcaaagc ttctttactc aaaggaactt tgtgaagctt tttcattttc
      781 atgaaatcag caggaatgtt ccaaatgctg ttggttgtat caatatcaga ccaccttgcg
      841 cgaacggctt cacccggacg aacccatgtc aacaattgcc attcaattag catacgtgtt
      901 tccaaccgga ttgacgcatt cgtcaaagat tccataaacc ttggcaattc gcttggggga
      961 agggcaggca tattttgctt ttttggttta ctgaatcttt gaccaaggtt gtcagccggg
     1021 ttgaactcaa taagttcttc agtagctgcc caccggaaga tttcattcag acgtgaaatg
     1081 atacggcgta gagtttccaa tacgcctcgt tgctcaatag gatcaaggtg ttgttttaag
     1141 agcttaggtc ggatctcatt gatagggaca ttacccagac cgggaaagac atttctctct
     1201 aagctgcgcc agatgtctgc tgcatggtct tgtgagatac ctgatgtctt taccttctca
     1261 tctaaccatt tccgcgctac ggcttggaga gtgtgctcag tagcactctt taatgccttc
     1321 gccttatcgt tgttatggat ttggggatca acaccatttg ccagaaagga gagatattca
     1381 tcacgtaagg ctctggctct tgcaagggta aggtgaggat atgtcccaag gctcattttg
     1441 gttcttttct tgctcactgg tactgcatac ctgaaatacc aatttttctt gcctcctttc
     1501 gccaaaggag cgattcgtag aatcagacca tcaccgtcaa acaagttgat ttctttatcg
     1561 gctggcttgg tacttttgat ttcagtgtca gtgagcttct tagcgatttt tgccattttg
     1621 ggaccctcgg tttttggacc cttcttagtg ggtcccattc agggtgccat aactcgtagt
     1681 tctcagcaat tctcactgga cgacaataga cgtaaaaaag cccgcagagc ttgtgctgtg
     1741 tgggcttagt agacttcatt gaacttcaaa caactaaaaa gtggtggagc tggcgggagt
     1801 tgaacccgcg tccgaaattc ctacatcctc ggtactacat gcttagtcag tctttacatt
     1861 cgcttgccaa ctgcggacgg acacgccact aacaaactag cctgattaag ttttaacgct
     1921 tcaaccccag gcagggcttc cacgcgatct cttttgggtt tgacctctct tgatccccgt
     1981 cctaagagcg gaggctaggg agagagggct ctaagcaggt tattaagctg ctaaagcgta
     2041 gttttcgtcg tttgcgacta ttttttgcgg ctttttacga ggccaaccgc ccctcggcat
     2101 gcaccttggg tttcgcaaat cccgtcgaat ccagaatcag ccccaatgtg taaaggtaag
     2161 tataccagat ttatgagcgc catgaccagc ctcaatggcg ttatcgttaa agatttagca
     2221 cccatgtagc ctgattttta ttcgattaag caatgggatg gcaacatttg tgtcggatgt
     2281 gatagccaat aagatgttca ttcgcgccgc cggagaggga ggcgcggtga ggaactggtc
     2341 aataattgga gtgcaggttt aacggtgggc gtttttcatg atacgtgctt tatccacctg
     2401 ccattcgcgt tctttgatat ctgaacgttt atcgtgctgt tttttacctt tggcgacgcc
     2461 gattttcact ttgcaccagg catttttcca gtacagggag agcgccacta cggtatagcc
     2521 ttctcgattg acgcgaccgt acaatgagtc cagttcgcgc tggttgagaa gtaacttgcg
     2581 ggtacgggta ggatcgcaca ccacatgcgt ggaggccacg gccattggcg tgatgttagc
     2641 gccaaacaga aatgcctctc cgtcacgcag aaggacgtag ctgtcgctga tattggcttt
     2701 tcctgcgcgc agggatttaa cctcccagcc ttgcagggca agtcccgctt cgaactcttc
     2761 ttcgataaag tattcgtgac gggcgcgctt gttaagcgcg atggtcgctg aaccaggttt
     2821 atgtgctttt ttcttcgtca taagcgtcgt gaatcatcgg taatctgaaa tcgaaaacac
     2881 cccatatcaa tcctgcgggg gacaaggctc tatcttagca tgaacccgat gttacccagc
     2941 gccgggatag cgtttttttt acagcaggat aaatgatatt atttgttgga tttttgttga
     3001 tggaaattgt tatgcctcag attagccgga ccgcactggt accctacagc gcggagcaaa
     3061 tgtatcagtt agtgaatgac gttcagtctt atcctcagtt tttgccgggt tgtaccggaa
     3121 gtcggattct ggagtccact cctgggcaga tgactgcggc ggtagatgtc tctaaggctg
     3181 ggatcagcaa aacgtttact acccgcaacc agttgaccag taaccaaagt attcttatga
     3241 atctggtgga tgggccgttc aagaaattga ttggtggatg gaagtttacg ccgctgagcc
     3301 aggaggcgtg tcgtatcgag tttcatctcg actttgagtt taccaataag ttgattgaac
     3361 tcgcctttgg tcgcgtgttt aaagagctgg cgtctaatat ggtccaggct tttacggttc
     3421 gtgcgaaaga ggtttacagt gccaggtaaa attgccgttg aggtggctta tgcgctacct
     3481 gagaagcagt acctgcagcg cgtgacgctg caggagggcg cgacggttga agaagctatt
     3541 cgcgccagtg gcttgctgga attgcgtacc gatatcgatt taactaaaaa caaagtcggc
     3601 atttacagcc gtccggcaaa actaagcgat agtgtgcatg atggcgatcg ggtggagatt
     3661 tatcgccctc tcattgccga tccgaaagag cttcgcaggc aacgagcaga aaaatcagcg
     3721 aataaataac agacagaaaa aaggtgctca ttgagcacct tttttaacgt ctttgagagc
     3781 aactttatta ttagttacca ctcagcgcag gtttgttatc aatattggtc aacacaccgc
     3841 tactgttaaa ggtcagcgtc agcgtttgct gcgttacacc ttcatgacct ggttgctggc
     3901 ggaagacata gaaccaggta ttcgtaccaa atggatcgga catcagcggt gtacccaatg
     3961 cgtacgcaac ttgttgttgc gtcatgccaa cacgtatttt ggatacgtcg ttagcggtca
     4021 gatagttccc ctggttgatg tcaggacggt aaaccactcg ctccagagtg gaacagcctg
     4081 cggtcaacat caatagtact gctgctgcag cagtcagcgt tttacagcgc atagtgattt
     4141 gattcctttt cgggcccgag cagtacgtgg ctcatctgta atatgccgat gataatagac
     4201 ctttcatcac tttaaaacct tttgctttcc ggtcttacgg cgttttgctg tttactctga
     4261 ccgtgaagca ggaaaaaagt ttacgctgca agcagttctt tcgcattcgc cagtgtatta
     4321 cgtgtgactt cactgccacc aagcaggcgc gccagctctt gtaaccgcgc ttttttattc
     4381 agggattgca tatgcgtttc tgtcatcgca ccatcggttt ctttgctgac aaaatagtgt
     4441 tgatgaccac atcccgcgac ttgtggcagg tgggtaacac acatcacctg agttgattcg
     4501 ccgagttgac gcagcagttt gccgacaact gccgctgttg gaccgctaat ccctacatcc
     4561 acttcatcaa aaatcagtgc cggggtttcc attttacgcg ccgtgatgac ctggattgcc
     4621 agtgcgatgc gggacaattc accaccggat gcgactttgg caataggctg cattggctga
     4681 cctgggttgg tggttacccg aaactcaata cgatcggcac cgtcagcgcc caggtgatgc
     4741 tcgtcaaatt taacatcgat cgtaaactgc ccatgcggca ttgagagcgc atgcatactg
     4801 tcggtgatca gctgtgcaag ttcttctgca tattgctggc gttgttggtg taatgcgcgc
     4861 gcgatttcca gtgcctgctg atgatgtttc gttaccgcca gcgcaagcgt ttcttgtgag
     4921 tcggcctgat cgtccagttg ctgctgttct tccagtagcg actggtaata ctgtggcaat
     4981 gcctcagggc tgacgtgatg tttacgtgcc agcgaaatct gttttgagat gcgctgttca
     5041 agttcaaata gtcggttggg atcgagatcc agacgatcgc agtagtggcg cagttcatcg
     5101 ctggcttcag caatctggat ggtagcttct tccagcatat caagtacgcc ggacagtttg
     5161 ctgtccatgc caatcaattc gctcaccagt tgtttagccg tgtaaagctg actttgcagg
     5221 tttgcgtctt caccgtcggc cattaatgcc aatgcattct ggctggtggt cagcaattga
     5281 ccgctgttcg ccagacgttt gtactcttcg tcgatttgtt caaactctcc gggctgcgga
     5341 ttaaattcgt taagttcttt taattggtat tgcagcagtt ccgcacgggc agcgcgttcc
     5401 tgacttaact gttgatgatg cgcgaggtca cggcagcttt gatgccacaa ctgataacgt
     5461 gctgtcattt cctggagtag agaggtttca ttggcatagc catcaagcag gaacttttgg
     5521 tgctcgggtt tggtgagtaa ctgatgagcg tgctgaccat ggatctgaat cagcaactga
     5581 cccagttcgc gcagttgtga cagaggaaca gctgtaccgt tgatgaaacc acgggagcga
     5641 ccatcgctgc tgatcacgcg acgaagcaaa cattcatgcc cgtcttcaag ctggttttct
     5701 tccagccagc gcagagccgc tggcgtatct ttcagagaaa aacgggcgca caggtcagcg
     5761 cgagcagcgc cggtacgcac catgtcggct tcagcgcgac caccgagaca aagaccgagg
     5821 gcatctattg caatagattt acccgcgccg gtctcgccag ttattacggt catgccgcta
     5881 tgaaaatcaa tctcaagctc acgaacgata gcaaagttgc tgatggtcag ttgtgccaac
     5941 atagtcgttt tcctgtatga aaaaccatta ctgttattgt gtacagtata aactggtttt
     6001 atatacagta aagaggctgg cgtaaaatta gaataatttt tttgaccagc cgagcttggt
     6061 gcttaatgtg ttgaaataac tgtaatcttt cggatgaatc agattcagat ggtaatcaca
     6121 gcgacgaatc aggacatctt caccttcctg aatcggcagt gctatctggc tgtcgcaact
     6181 gatttccagg tcgttacggc gatgcgaaaa acgcagacgg atcgtgctgc tgctgtttat
     6241 gaccagtggt cgtgctgaca acgtatgcgg gaacatgggc accagggtaa tcgcatccag
     6301 agagggggtc agaataggac cgcctgcaga gagggaatag gcggtggagc ctgttggcgt
     6361 cgaaataatt agtccatcag atcgctgaga aaacgcaaag atctcgtcga tatacacttc
     6421 gaactcaatc atatgcgcca ctttgcctgg atgaagcacc acttcattta tcgcggtgct
     6481 gatgcgtttc tggcaatctt gctgacagac ttgcgcttcc agcaaaaaac gtttctcgct
     6541 gatgtagtgg ccttccagca catcggctaa ctgttgctgg gcgttatcgg ggtcaaggtc
     6601 agtcaggaaa cccaggttgc cacggttgat tccaataact ttaatatcgt aacgggcgag
     6661 tgtgcgtgcc gcgcccagca tattaccgtc gccaccaacg actaccgcga gatcagctag
     6721 ttgcccaatc tccgcgagcg tgccagtttt cacattcttc agttgcagtt cgtgagcgat
     6781 ttgttgctca acgatgacct cgtaaccttt tgtgcacagc cagcggtaga gcatttcatg
     6841 tgttgtcagt gcagtggggt gccgtgggtg tcccacaatg ccaatacact tgaaatgatt
     6901 attcattttt ccgaggtcct tgttacgaag attgatgaca atgtgagtgc ttcccttgaa
     6961 accctgaaac tgatccccat aataagcgaa gttagcgaga tgaatgcgaa aaaaacgcgg
     7021 agaaattcat gagtagtaaa gaacagaaaa cgcctgaggg gcaagccccg gaagaaatta
     7081 tcatggatca gcacgaagag attgaggcag ttgagccaga agcttctgct gagcaggtgg
     7141 atccgcgcga tgaaaaaatt gcgaatctcg aagctcagct ggctgaagcc cagacccgtg
     7201 aacgtgacgg cattttgcgt gtaaaagccg aaatggaaaa cctgcgtcga cgtactgaac
     7261 tggatattga aaaagcccac aaattcgcgc tggagaaatt catcaacgaa ttgctgccgg
     7321 tgattgatag cctggatcgt gcgctggaag tggctgataa agctaacccg gatatgtctg
     7381 cgatggttga aggcattgag ctgacgctga agtcgatgct ggatgttgtg cgtaagtttg
     7441 gtgttgaagt gatcgccgaa actaacgtgc cgctggaccc gaatgtgcat caggctatcg
     7501 caatggtgga atctgatgac gttgcgccag gtaacgtact gggcattatg cagaagggtt
     7561 atacgctgaa tggtcgtacg attcgtgcgg cgatggtaac tgtagcgaaa gcaaaagcgt
     7621 aatttctgtt ttcgtaataa ttcacggccc tgcatgcgaa tgcagggccg ttttcgttac
     7681 tccgccacac tctcgcgcag cggttttaca ggaaagactt ttacctgctt aatcatattg
     7741 tcctgaacgt cgagaatatc gatatcgtac tcgccaatat gcacgcgggt gccagcgaca
     7801 gggatctctt ccagagcttc aagaatgacg ccattaaccg tgcgggcatc gtcttcaggt
     7861 agatgccagt taaaggcttt gttgatttcc cgcacgttgg cggtgccatc gataatcacc
     7921 gaaccgtcgt tttgcggcgt gacctcttcg gcaagtgttg gcgacatcga cgtagtgaaa
     7981 tcgccgacaa tctcttccag aatatcttca accgtcacca gcccctgaat gtctccatac
     8041 tcgttgacga ccaggccgac tttctttttg ttgcgctgaa actttaccaa ctgcgtgctg
     8101 agcggcgtac cttccggcac aaaatagatc tcgtccgcgg cgcgcagcat ggtttctttg
     8161 gtgaactctt ttttctccga catcaaccgc caggcttcac gtactcgcag catactgatg
     8221 gcgtcgtcca gcgaatcacg gtagagcacg atgcgcccgt gaggtgagtg ggagagttgg
     8281 cgcagaatcg atttccagtc atcgttgata tcaataccga taatttcact gcgcggcacc
     8341 atgatgtcat caacggtcat tttttccaga tcgagcaccg acagcagcat atcctgattg
     8401 cgacgggaaa tttgtgagcg tgattcgtgc acgatagtgc gcaactcttc tttgctcaaa
     8461 gagccgctaa ccacgatatc ggttttgata cccatcatgc gcatcagcat acgggtgata
     8521 gcattcagca accagaccag cggcatcatc aaaatttgca gcggagccag cagaaaacta
     8581 ctcggataag cgactttttc cgggtacagc gcggcaatgg ttttcggcaa tacctcagca
     8641 aataccagta cgacaaaagt cagcacacca gtcgcaattg ccacgcccgc atcgccgtac
     8701 aaacgcatcc caacaatagt gccgagcgcg gaggcaagaa tattgaccag gttattgccg
     8761 attaacacca ggcttatcag gcggtctggc ttacgcagca atttttcgac gcgtttggcc
     8821 gagcgattac cctgtttcgc catatgtcgc agacgatatc ggttgagggt catcattccg
     8881 gtttcggacc cggaaaaata ggctgaaatg accaccatga tgatcagaat aatgatcaac
     8941 gtagtagtag aaatgtgttc caggggaaac tccttttctg ggtttagctg attaactgct
     9001 ggacaattcg gctgccgaag taggccagtg tcagaattac cgcgcccgca acgttaaacc
     9061 agacgacgcg gcgtccacgc catccttcat ggtaatgtcc ccacagcagc acaatataga
     9121 caaaccacgc cacgatagag agcacagcct tgtcgatatt ttccatgcta aataggttgt
     9181 gcatgtagaa caggccagtg caaagcgtga gcgttagcag caccacgcca atctgcgtga
     9241 tgtggaacat tttacgctcg atactcatca atggcggcat ttcctggtta aatgccagct
     9301 tcttgttctt cagttggtaa tcaatccacg ccagttgcag cgcgtacagg gcggcgataa
     9361 ttagcgtggc ataggaaaag agcgataagc caatgtgcac cagcatccca ggcgttgctt
     9421 ccagatgggt gatgtattca ttgggcatga aggtcgccag cgccaggttg ataagcgcaa
     9481 aggcatagac aatgggtagc agcaaccagc cacgattgcg agaagccaca atggtcatta
     9541 ccgtacagat catcaaactg accaatgaac caacgttcag caggctgagg ttttgtccgc
     9601 tatcaccgtc gggcaggatg cgggcttcca gagcgattgc gtggcagacc agcgcaatga
     9661 ccgcagaaat aatagccatg cgccgccagc cgccgttttt ttgcagcaga ccgggaacaa
     9721 tcagcgcaag actgacggag taggcgacaa gcgcgagcag agcaaaaacg ggcatagtga
     9781 tgtcgacagt ttgagcaata agaaagagaa gcagtatagc gtcaggtgaa cgctgctcca
     9841 accgttgcat aacaacaaag acgccttcat gttatactgc ggcaaaatac tgatgatgtg
     9901 tcgcgattgc ggccaaccgt ttccacccca ggcgagagac aatgtttgat aatttaaccg
     9961 atcgtttgtc gcgcacgctg cgcaatatca gtggccgtgg acgcctcact gaagacaacg
    10021 taaaagatac gctgcgcgaa gtgcgcatgg cgctgctgga ggcggacgtc gctctgccgg
    10081 tagtgcgtga gtttatcaat cgcgtaaaag agaaagcggt tggtcatgaa gttaataaga
    10141 gcctgacgcc ggggcaggag ttcgtcaaaa tcgtccgtaa cgaactggtt gcggcgatgg
    10201 gcgaagagaa ccagaccctg aacctggcgg cgcaaccgcc tgcggtcgtg ctgatggcgg
    10261 gcctgcaagg tgccggtaaa acaaccagcg ttggtaaact cggtaagttc ctgcgcgaga
    10321 agcacaagaa gaaagtgctg gtggtttctg ccgacgttta tcgcccggcg gcaatcaaac
    10381 agcttgagac gctggcagag caggtgggcg ttgatttctt cccttctgat gttggtcaga
    10441 agccggtaga tatcgttaac gcggcgctga aagaagccaa actgaaattc tacgacgtgc
    10501 tgctggtgga taccgctggt cgtctgcacg ttgacgaagc gatgatggac gagatcaaac
    10561 aagtccatgc gtcgattaac ccggttgaaa ccctgtttgt ggttgacgcc atgaccggtc
    10621 aggatgcggc caatacggca aaagcattca atgaagcgtt accgcttacc ggcgtagtgt
    10681 tgaccaaagt ggacggcgat gcccgcggcg gtgcggcgct ctctattcgt cacatcactg
    10741 gcaaaccgat caagtttctc ggtgttggcg agaaaactga ggcgctggag ccgttccatc
    10801 cggaccgcat cgcgtcgcgt attctcggca tgggcgacgt actgtcgctg atcgaagata
    10861 tcgaaagcaa agttgaccgc gcgcaggcag agaaattagc cagcaagctg aaaaaaggcg
    10921 acggcttcga tctcaacgat tttcttgagc aactgcgcca gatgaaaaat atgggcggca
    10981 tggctagcct gatgggcaag ctgccgggca tggggcagat cccggataat gttaagtcgc
    11041 agatggacga taaagtgctg gtgcgtatgg aagccatcat caactcgatg acgatgaaag
    11101 agcgcgctaa gccagaaatc atcaaaggtt cgcgtaaacg ccgtattgct gccggttgcg
    11161 gtatgcaggt gcaggacgtt aaccgtcttc tgaaacagtt cgacgacatg cagcgcatga
    11221 tgaagaaaat gaagaagggc ggaatggcga agatgatgag aagcatgaag ggtatgatgc
    11281 ccccaggctt ccctggtcgc taatcggcct ggcttgtttg ccattttggc accgggttgt
    11341 gctcgtcatc ctcacgtact gcgtgtacgc tccggtgact gcgcgcactc cggcaccaaa
    11401 ctggctgcac cgccgacggc cttttacagc agagttagca actgttgatt gcaattcccg
    11461 caaaaatgag taaaattttc gggcttttaa tatgacaccg gactccgttc ctcgatgggg
    11521 tccggttgtt ttattcacac aagaggatgt tatggtaact attcgtttag cacgtcacgg
    11581 cgctaaaaag cgtccgttct accaggttgt tgtcgctgac agccgtaatg cacgcaacgg
    11641 tcgcttcatc gagcgcgttg gtttcttcaa cccaatcgct agcgaaaaag aagaaggcac
    11701 tcgcctggat ctggatcgca tcgctcactg ggttggccag ggcgcaacta tttctgatcg
    11761 cgttgctgcg ctgatcaaag aagtaaacaa agcagcttaa tctgtcacgg tggtcatgat
    11821 gagcaaacaa ctcaccgcgc aagcacctgt tgatcccatc gttttgggga aaatgggttc
    11881 gtcttacggt attcgtgggt ggctcagagt gttttcttcc accgaagacg ccgaaagcat
    11941 ttttgactat cagccctggt ttatccagaa ggcgggtcag tggcagcaag tccagctgga
    12001 aagctggaag caccacaatc aggacatgat catcaagctg aaaggcgttg acgatcgtga
    12061 tgcggcgaac ctgctgacga attgtgaaat tgtcgtggat tcatcgcagc tgcctcagct
    12121 tgaagagggg gactactact ggaaagacct gatgggctgc caggtagtaa ccactgaagg
    12181 ctacgatctc ggtaaagtcg tcgatatgat ggaaaccgga tctaatgacg ttctcgtcat
    12241 taaggcaaac ctgaaagatg cgtttggtat caaggaacgt ctcgtaccgt tcctcgatgg
    12301 gcaggttatc aagaaagtcg atctcactac tcgttcaatc gaagtagatt gggatcctgg
    12361 tttttaaacc accggataaa cggtaaaaga cggcgctatg tggattggca taattagcct
    12421 gtttcctgaa atgttccgcg caattaccga ttacggggta actggccggg cagttaaaaa
    12481 tggcctgctg agcatccaga gttggagtcc tcgcgacttc acgcatgacc ggcaccgtac
    12541 cgtggacgat cgtccttacg gcggcggacc ggggatgtta atgatggtgc aacccttgcg
    12601 ggacgccatt catgcagcaa aagccgcggc gggtgaaggc gcaaaggtga tttatctgtc
    12661 accacaggga cgcaagcttg atcaagcggg cgtcagcgaa ctggcaacga atcaaaaatt
    12721 gattctggtg tgcggtcgct acgaaggtat agatgagcgc gtgatccaaa ccgaaattga
    12781 cgaagaatgg tcaatcggcg attacgttct cagtggtggt gagttaccag caatgacgct
    12841 gattgactcc gtttcccggt ttattccggg agtactggga catgaagcct cggcaacgga
    12901 agattccttt gctgaaggat tgctggattg cccgcactat acgcggcctg aggtgttaga
    12961 agggatggaa gttccgccag tgttactgtc gggcaaccat gccgagatac gtcgctggcg
    13021 tttgaaacag tcgctgggcc gtacctggct tagaagacct gaacttctgg aaaacctggc
    13081 tctgactgaa gagcaagcaa ggttgctggc ggagttcaaa acggaacacg cacaacagca
    13141 acataaacat gatgggatgg cgtaagcccc cgagatatca gtttacccag gataagagat
    13201 taaattatga gcaacattat taagcaactt gaacaagagc agatgaagca ggacgtacct
    13261 tccttccgtc cgggtgatac cgtggaagtg aaagtatggg ttgttgaagg ttccaaaaaa
    13321 cgtctgcagg cattcgaggg cgtggttatc gctattcgta accgcggtct gcactctgca
    13381 ttcactgttc gtaaaatttc caacggcgaa ggcgttgagc gtgtcttcca gactcactct
    13441 ccggtagttg acagcatttc tgtcaaacgt cgtggtgctg ttcgtaaagc taaactgtac
    13501 tacctgcgtg agcgtactgg taaggctgct cgtatcaaag agcgtcttaa ctaagatttc
    13561 gcttaagcga catcctgtta agaagggctg gccaattggc tggccctttt tttgtctgtt
    13621 tgctcgtgtt ttaaggggtt gtaatcacca ctgcgacgcg gcggttctcg gcgcggccct
    13681 gggcggtctt gttactggct atgggatatt tttttcctaa accctgtgtg gtgagattgc
    13741 tgcgtggaat ttgtccaccc atagcccatg catcggccac gacattcgcc cgtttcaatg
    13801 ataagccttc gttgtaactg tcttcaccat agttatcggt gtgtccatcc atacgggcat
    13861 gtgttagccc tgtcgaggcc aatttggctg ccatggtttg gatctgttgc tggctttccg
    13921 ggagcaattt gtagtcattt tttgcgaaca gaatggcatc tgataagccc agcgaccagt
    13981 cgccggcgga ttcagtaaat ccataagatt gcatagcggc gacttgctca ggagtaaact
    14041 ttccctgagg ggactggcag ccagtcagta ttagtgaggt gaaaatcagg ggtgctacca
    14101 ggtgctttat catatcgata tatccttgtt atctcaccag cttttcggca cgctggtgtt
    14161 tggcctgata catattgtga tcggcaagct cttgtaattt ttccgcagag gcgtgctcaa
    14221 tggtcatcgc gtaaccaatg cttaatgtca tggtggtctg atggccatta tgaagatcaa
    14281 acgggagatt aaagatttgt gtcagtgctg agcatatctg ctgcacttca gattccgact
    14341 gtacatcata gagcaccata gcgaattcat cgccgcccag gcggtatgct ttatgtcgca
    14401 gcccgccaaa ttcagctaac cgttttgcga tttcaatcaa gactctatcg cccgtcgcat
    14461 gaccccaggt atcattgata tatttgaaat tatcgccatc aagaaatagt aacgccgacg
    14521 tttttcgggc atcggaattg ttcatcaacg tattgatgcc gctacgaaac gctgcgcggt
    14581 tagccagccc ggttaatggg tcatgtagcg cggtacgcag aagctgcgca tttttggcct
    14641 gtaaacgaag ctgccactct tccatttcat ccagcagact gttgaagtcg agagcgaagc
    14701 ggtgaaactc agcgatacgt tcttccgaaa ctcgtcggga aaaattgcgg ttggaacgca
    14761 catcatgtac gacatcggtg atatttttca gcgcttctac caggccattg tgcaaatggc
    14821 gggtgagggt aattgcgatg cctgatgcca gcagaataca accggtcagt acggcgagcg
    14881 aaaaccagat aaaatggctg attgaactgt cgcgagcggt taagcgtact tcgccaatgg
    14941 tttcaccatt gtgacgaatc ggctgaatga tgggggcggg gaagagccag tggcttatga
    15001 aattgctgaa agtatcgcct ggatccttac gggtgtaatg ccaggacgcc agaatatttt
    15061 gctgcttatc acgtacttct gcagttgaaa attgcccttg ctggcccagc gctgccagtg
    15121 tttcagttgc tgcagggcca tcggcaaaaa cgacagctgc ttccagactg taagtcattg
    15181 ttgctgctgt cagtgccagg tttttttgcg cgtactgttt cagggtcagc accgaggtca
    15241 cggaaagcag caaccagatc agcatcatag tgataaatat gctggtcata ctgatgttgc
    15301 gtaatgctct tttaaacgtg gggcgcttat taagagaatt atcgttatcc atcatttttc
    15361 ttccgtgcga gcattaagac atccgggttg acctttacac cgctacgcga taaggcatcc
    15421 aggtttacgg caaatctgac gtcattattg tggatgatca gacaaaaggc gctaccaata
    15481 atgcactcgg tattttgttc ggcaattaat aataacgcct ttgacggata ttgttcggtt
    15541 aattccatct ggaatgtcgg tgactcgttg ccaaaataaa aaccattgca gcctgaaatc
    15601 atcgcctctt gttgagtgtg aatgatgaca ggcagataag gcaaagatgt cgcggcattc
    15661 tcttgtaggg cggtactaaa acgtgaagat gaaaagatac ataactttgg tggccctgat
    15721 agcgcaggcc agcgggtgta actgacaata ccggaaacca tcatacgcac gtttttcgca
    15781 acgtcagaag gctcctgagc gagtattggt gctcccgtca gcaggagaat cagaagtaag
    15841 aacagtcggt gagaaaaacg cattcaggga tccccaccat cttcgctcga aatgcatcga
    15901 tattttttca gaatgctcat taaaatatca ttttttcatg cgatcgtcat caatgtgaga
    15961 aataaaacac aatgagtaaa atcttatgtt taatttattt gtggggtttt aattaattta
    16021 atcgtattgt gctggcattt tcatcagccc ctttttgcca tacttcatgc agttggctgg
    16081 cattttcaac attgttgcag ctggcaggaa agcttttacc ggaaagtccc cgggcataag
    16141 taaaatcggt ctggcaagtt ttcttttgtc cttcggcata tcctttaagg tatagaccgc
    16201 gatccgcctg tgaatcgcta aatgcatcgt catcttttat ggcgctgccc gatatcgcat
    16261 cttccatacc gacatcatac cagtcggtgc tggtcaaggt tggcgcgtga gtataaggat
    16321 caatctgaca tccgctaacc agtaaagcca acaagggggc gataaacttt ttcatcattt
    16381 ctttctcctt tttcaaagca tagcggattg ttttcaaagg gagtgtaaat ttatctatac
    16441 agaagtaagg gttgaaatcg cgactaaatt gcctgtgtaa ataaaaatgt acgaaatatg
    16501 gattgaaaac tttactttat gtgttatcgt tacgtcatcc tcgctgagga tcaactatcg
    16561 caaacgagca taaacaggat cgccatcatg caaaaagacg cgctgaataa cgtacatatt
    16621 accgacgaac aggttttaat gactccggaa caactgaagg ccgcttttcc attgagcctg
    16681 caacaagaag cccagattgc tgactcgcgt agaaccattt cagatattat cgccgggcgc
    16741 gatcctcgtc tgctggtagt atgtggtcct tgttccattc atgatccgga aactgctctg
    16801 gaatatgctc gtcgatttaa agcccttgcc gcagaggtca gcgatagcct ctatctggta
    16861 atgcgcgtct attttgaaaa accccgtacc actgtcggct ggaaagggtt aattaacgat
    16921 ccccatatgg atggctcttt tgatgtagaa gccgggctgc agatcgcgcg taaattgctg
    16981 cttgagctgg tgaatatggg actgccactg gcgacggaag cgttagatcc gaatagcccg
    17041 caatacctgg gcgatctgtt tagctggtca gcaattggtg ctcgtacaac ggaatcgcaa
    17101 actcaccgtg aaatggcctc cgggctttcc atgccggttg gttttaaaaa cggcaccgac
    17161 ggcagtctgg caacagcaat taacgctatg cgcgccgccg cccagccgca ccgttttgtt
    17221 ggcattaacc aggcagggca ggttgcgttg ctacaaactc aggggaatcc ggacgggcat
    17281 gtcatcctgc gcggtggtaa agcgccgaac tatagccctg cggatgttgc gcaatgtgaa
    17341 aaagagatgg aacaggcggg actgcgcccg tctctgatgg tagattgcag ccacggtaat
    17401 tccaataaag attatcgccg tcagcctgcg gtggcagaat ccgtggttgc tcaaatcaaa
    17461 gatggcaatc gctcaattat tggtctgatg atcgaaagta atatccacga gggcaatcag
    17521 tcttctgagc aaccgcgcag tgaaatgaaa tacggtgtat ccgtaaccga tgcctgcatt
    17581 agctgggaaa tgaccgatgc cttgctgcgt gaaattcatc aggatctgaa cgggcagctg
    17641 acggctcgcg tggcttaaga ggtttattat ggttgctgaa ttgaccgcat tacgcgatca
    17701 aattgatgaa gtcgataaag cgctgctgaa tttattagcg aagcgtctgg aactggttgc
    17761 tgaagtgggc gaggtgaaaa gccgctttgg actgcctatt tatgttccgg agcgcgaggc
    17821 atctatgttg gcctcgcgtc gtgcagaggc ggaagctctg ggtgtaccgc cagatctgat
    17881 tgaggatgtt ttgcgtcggg tgatgcgtga atcttactcc agtgaaaacg acaaaggatt
    17941 taaaacactt tgtccgtcac tgcgtccggt ggttatcgtc ggcggtggcg gtcagatggg
    18001 acgcctgttc gagaagatgc tgacactatc gggttatcag gtgcggattc tggagcaaca
    18061 tgactgggat cgagcggctg atattgttgc cgatgccgga atggtgattg ttagtgtgcc
    18121 aatccacgtt actgagcaag ttatcggcaa attaccgcct ttaccgaaag attgtattct
    18181 ggttgatctg gcatcagtga aaaatggacc attacaggcc atgctggcgg cgcacgatgg
    18241 cccggtactg gggttacacc cgatgttcgg cccggacagc ggtagcctgg caaagcaagt
    18301 tgtggtctgg tgtgatggac gtaagccgga agcataccaa tggtttctgg agcaaattca
    18361 ggtctggggc gctcggctgc atcgtattag cgctgtcgag cacgatcaga atatggcgtt
    18421 tattcaggct ctgcgccact ttgctacttt tgcttatggg ctgcatctgg cagaagaaaa
    18481 tgttcagctt gagcaacttc tggcgctctc ttcgccgatt taccgccttg agctggcgat
    18541 ggtcgggcga ctgtttgctc aggatccgca gctttatgcc gacattatta tgtcgtcaga
    18601 gcgtaatctg gcgttaatca aacgttacta taagcgtttc ggcgaggcga ttgagttgct
    18661 ggagcagggc gataagcagg cgtttattga cagtttccgc aaggtggagc actggttcgg
    18721 cgattacgca cagcgttttc agagtgaaag ccgcgtgtta ttgcgtcagg cgaatgacaa
    18781 ccgccagtaa taatccagtg ccggatgatt cacatcatcc ggcacctttt catcaggttg
    18841 gatcaacagg cactacgttc tcacttgggt aacagcccaa taccttcatt gaacgggtaa
    18901 tttcccctaa ctctttcaat gctttttgca tttccgctga ttcaagattg gcctgaatat
    18961 ccagataaaa catctcttcc catggattac cgtgaatcgg gcgtgattcc agacgggtca
    19021 taatcagatt gtggttgcgc agcaccagca acgcttcaac cagcgcaccg gcttgttgcc
    19081 cggtcgccat taacaacgtc gttttcgccg gaacctggtc agacacgtta atggctttac
    19141 gtgccaacac cacaaatcgg gtgaagtttt gttgctgatt cgcttcaata cgctccagta
    19201 cctgcaaacc gtacaaagtg ccgccagctt cgcttcccaa cgcagcaaca tgcggtgatt
    19261 ttgcctgtgc aaccttttcc attgccgcag acgtactttc ggtatattca atcttccagt
    19321 gaggataacg attaaggaat ttgctgcatt gctggaatgg ctgcggatgg ctgtagaccg
    19381 tattaatagt ggataaatca gtcgtgccgg agaccaacaa acaatggtcg atagttaacg
    19441 tcatctcgcc aacaatcgac aagctggtat gttgcagcag atcgtaaacg tcgtttatgg
    19501 caccggagct ggtattttca atcggtacga cggcatagtc ggcctggccg gtttccacct
    19561 gattaaaaat atcggcaaat ttggcgcagc cactttcaat gaattgctca aagtgacggg
    19621 cagcatactg gcgcgccgca agatgggaat aagaaccttt ggggccgaga aaagcgatgc
    19681 gtgctgagtg cggattaatt ttattgagat gttgctggag caaagcctgc tgagttaata
    19741 cggaatcttc aatgatgagc tggaacaggc gagtaatgta atgggcgtcc agatggtgcg
    19801 ctttaccgag cgtaattaat ctttccagta aatcgcgttc acgatcaata tctcgtaccg
    19861 ggcgatgcga gagcagtttg gcttttccta cctcgacggc caattcgcgc cgctctgcca
    19921 gtaatgctaa taatttttca tccagcgcgc tgattttctc tcgcagcgcc agtaacgggt
    19981 tttccgatgt catagtgttg cctttttgtt atcaataaaa aaggcccccc gatttgggag
    20041 gccttattgt tcgtcttcgc attctgtttc acacgacgaa acgcctccca ttcaggggaa
    20101 ggtaaaaaag aatgcgaaga aaaacggtgt gtgtttcatg tttgtttcct taagtgactt
    20161 tagtacagta cccgtactgt tttcacgctg tcaacaaaaa acgcgcccga aggcgcgttg
    20221 gcgatacact caatataaag gactactctt cttcaacttc ttcgacgaag ttggcgtctt
    20281 tcaccgatgt tgcggcacga cgtgcttcgc ctttgtgctg cagtttattg agctgccgtt
    20341 ccagcttgtt gatcaattcg ttaattgcag tgtacatatc ttcatgttta ccactggcaa
    20401 ccagaacgcc gttaggtgta ttgattgtgg cgtcagcaac aaacccttgt ggctctttgg
    20461 acagaatgat atgtggatta atcagatgtg tttgccattt ttccagtttg gcgagacggt
    20521 ctgcgacatg ttggcggatg gccggagtaa tttccatttg tttgctggta atgttcattg
    20581 tcataaattt tacctcttgt cttcccgtct tggtgaattc agcataccgc tcctgatgtc
    20641 aaaatgtgtg atgggaatct cataattttg tcactttttg tcaacgaatc ttttttgtga
    20701 gaaatcgcag gaagaggtgt ttttttactt gaggaatatc tcaaagcgag ccatatttga
    20761 tgagatcgat agtgactaaa tcgcttcagt ttcacaacta acagaataaa aaaacggcag
    20821 ctcaagggct gccgttttgt atttcaggtt tctgttatgt attgctgctg tttgcggcga
    20881 tgattttcgc tactttttca gcttgcgcat tcatctgcat ctgacggtat gcattttcca
    20941 tcagcggcag cgcatcacgc gtagcctggg tatccgggta gtcgcgcaac attccttcta
    21001 cgcggttaac gacggcaacc catgcgccac gttctgtata gtactcggcc acggagtatt
    21061 catatttcgc cagacgatct ttcaggaata ccagacgttt ggtggcatcg gtggtgtact
    21121 gactgtttgg atagccgcgc accagtttgg aaaagtcact aaacgcagct cgtgcatgtt
    21181 gaggatcgcg atcgctacgg tcaacgccaa agaacccttg cagcgcactg tcatccagcg
    21241 ccatattggt caggccacgc atgtacatga cataatcgat attcggatgg gtcgggttaa
    21301 ggcgaataaa acgatcgatg gcagcctgcg ctaacggcaa atcggcgttt ttatagtagg
    21361 cgtagatgag atccagctgc acctgctgcg aatacggacc aaacggatag cgattatcta
    21421 acgcttccag ttgcgttatt gcctgtctcc agttaccgtc ctgcagcttt tgttgtgcag
    21481 tcgcgtaaat ttcatttggc ggattatcag gtacttcttc ctttgacccc gagcaacccg
    21541 ccaaaaacag gcttagtgtg gcggctgcca ccagatattt catgcgcgtc atgacgtttt
    21601 gactttcctc aaaatgtaat acgggagatt ctctgttcct gctcccggtt aagaccagct
    21661 acaatagcac actatattaa acggcaaagc cgtaaaaccc caacgataaa cgaagaagca
    21721 gtatatatgg cacaacgagt acagctcact gcaacggtgt ccgaaaacca actcggtcaa
    21781 cgcttagatc aggctttggc cgaaatgttc ccggattatt cacgttcgcg aataaaagaa
    21841 tggatcctcg accagcgcgt gctggtaaac ggcaaagttt gtgataagcc gaaagaaaaa
    21901 gtattgggtg gcgagcaggt tgccatcaac gctgagattg aagaagaagc gcgttttgaa
    21961 ccgcaggata tcccgctgga tatcgtctat gaagatgaag atatcatcgt cattaataaa
    22021 ccgcgcgacc tggtggtaca tcctggcgcg ggtaacccgg atggcacggt actgaatgcg
    22081 ttgcttcatt actatccgcc cattgccgat gtaccacgtg cgggcatcgt ccatcgtctg
    22141 gataaagaca ccactggcct gatggttgtg gcaaaaaccg ttccggctca gacgcgttta
    22201 gtcgaatctt tgcaacggcg tgaaattact cgtgagtatg aagcggtggc gattggtcat
    22261 atgaccgctg gcggtacagt agatgaaccc atcagccgcc acccgaccaa acgtactcac
    22321 atggcggtgc atccgatggg caaaccggcg gtgactcact atcgcatcat ggaacacttc
    22381 cgtgtgcaca cgcgtctgcg gttgcgtctg gaaactggac gtacgcacca gatccgcgtg
    22441 catatggccc atatcactca tccgctggtg ggcgatccgg tttatggtgg ccgtccgcgt
    22501 ccgccaaaag gtgcttcgga agcatttatc tccatgctgc gtaagtttga ccgccaggcg
    22561 cttcatgcaa ccatgctgcg tctttatcac ccgatctccg gcatcgaaat ggaatggcat
    22621 gcgcctattc cacaagatat ggtggagctg attgaggtga tgcgcgccga tttcgaagag
    22681 cataaggatg aagtggactg gttatgagta agctgattgt cccgcagtgg ccgctaccaa
    22741 aaggtgttgc ggcctgtagc tcttctcgta tcggcggcgt gagcttgccc ccgtatgact
    22801 cgctcaacct cggtgcccat tgtggcgata acccggatca cgttgaggag aatcgcaagc
    22861 gactttttgc tgcgggcaat ttgccttcta aaccggtctg gcttgagcag gtacacggca
    22921 aagatgtgct taagcttact ggcgaacctt atgcctcaaa acgagcagat gcctcttata
    22981 gcaatacgcc cggcacggtt tgcgcagtga tgactgccga ctgcctccct gtgctgtttt
    23041 gcaatcgagc gggaacggaa gtcgccgccg ctcatgctgg ctggcgtgga ctgtgcgcag
    23101 gcgtactgga agagacggtt tcctgttttg ctgataatcc ggaaaatatt ctcgcctggt
    23161 tagggccggc aattggtcca cgcgcgttcg aagtgggggt ggaggttcgc gaggcgttta
    23221 tggcagtaga cgctaaagca agtgcagctt tcattcagca tggtgataag tatctggcgg
    23281 atatttatca gcttgcccgg cagcgtctgg cgaacgtggg tgttgagcaa attttcggcg
    23341 gcgaccgttg tacatatacg gaaaatgaga ctttcttctc ttatcgtcgc gacaagacca
    23401 ccggtcgtat ggcaagtttc atttggctga tataacctaa agaatcaaga cgatccggta
    23461 cgcgtgattt tcttttcaca ttaatctggt caataacctt gaataattga gggatgacct
    23521 catttaatct ccagtagcaa ctttgatccg ttatgggagg agttatgcgt ctggatcgtc
    23581 ttactaataa attccagctt gctcttgccg atgcccaatc acttgcactc gggcacgaca
    23641 accaatttat cgaaccactt catttaatga gcgccctgct gaatcaggaa gggggttcgg
    23701 ttagtccttt attaacatcc gctggcataa atgctggcca gttgcgcaca gatatcaatc
    23761 aggcattaaa tcgtttaccg caggttgaag gtactggtgg tgatgtccag ccatcacagg
    23821 atctggtgcg cgttcttaat ctttgcgaca agctggcgca aaaacgtggt gataacttta
    23881 tctcgtcaga actgttcgtt ctggcggcac ttgagtctcg cggcacgctg gccgacatcc
    23941 tgaaagcagc aggggcgacc accgccaaca ttactcaagc gattgaacaa atgcgtggag
    24001 gtgaaagcgt gaacgatcaa ggtgctgaag accaacgtca ggctttgaaa aaatatacca
    24061 tcgaccttac cgaacgagcc gaacagggca aactcgatcc ggtgattggt cgtgatgaag
    24121 aaattcgccg taccattcag gtgctgcaac gtcgtactaa aaataacccg gtactgattg
    24181 gtgaacccgg cgtcggtaaa actgccatcg ttgaaggtct ggcgcagcgt attatcaacg
    24241 gcgaagtgcc ggaaggattg aaaggccgcc gcgtactggc gctggatatg ggcgcgctgg
    24301 tggctggggc gaaatatcgc ggtgagtttg aagaacgttt aaaaggcgtg cttaacgatc
    24361 ttgccaaaca ggaaggcaac gtcatcctgt ttatcgacga attacatacc atggtcggcg
    24421 cgggtaaagc cgatggcgca atggacgccg gaaacatgct gaaaccggcg ctggcgcgtg
    24481 gtgaattgca ctgcgtaggt gccacgacgc ttgacgaata tcgccagtac atcgaaaaag
    24541 atgctgcgct ggaacgtcgt ttccagaaag tgtttgttgc cgagccttct gttgaagata
    24601 ccattgcgat tctgcgtggc ctgaaagaac gttacgaatt gcaccaccat gtgcaaatta
    24661 ctgacccggc aattgttgca gcggcgacgt tgtctcatcg ctacattgct gaccgtcagc
    24721 tgccggataa agccatcgac ctgatcgatg aagcagcatc cagcattcgt atgcagattg
    24781 actcaaaacc agaagaactc gaccgactcg atcgtcgtat catccagctc aaactggaac
    24841 aacaggcgtt aatgaaagag tctgatgaag ccagtaaaaa acgcctggat atgctcaacg
    24901 aagaactgag cgacaaagaa cgtcagtact ccgagttaga agaagagtgg aaagcagaga
    24961 aggcatcgct ttctggtacg cagaccatta aagcggaact ggaacaggcg aaaatcgcta
    25021 ttgaacaggc tcgccgtgtg ggggacctgg cgcggatgtc tgaactgcaa tacggcaaaa
    25081 tcccggaact ggaaaagcaa ctggaagccg caacgcagct cgaaggcaaa actatgcgtc
    25141 tgttgcgtaa taaagtgacc gacgccgaaa ttgctgaagt gctggcgcgt tggacgggga
    25201 ttccggtttc tcgcatgatg gaaagcgagc gcgaaaaact gctgcgtatg gagcaagaac
    25261 tgcaccatcg cgtcattggt cagaacgaag cggttgatgc ggtatctaac gctattcgcc
    25321 gtagccgtgc ggggttggcg gatccaaatc gcccgattgg ttcattcctg ttcctcggcc
    25381 caacgggtgt ggggaaaact gagctttgta aggcgctggc gaactttatg tttgatagcg
    25441 acgaggcgat ggtccgtatc gatatgtccg agtttatgga gaaacactcg gtgtctcgtc
    25501 tggttggtgc gcctccggga tatgtcggtt atgaagaagg tggctacctg accgaagctg
    25561 tgcgtcgtcg tccgtattcc gtcatcctgc tggatgaagt ggaaaaagcg catccggatg
    25621 tcttcaacat tctgttgcag gtactggatg atggtcgtct gactgacggg caggggagaa
    25681 cggtcgactt ccgtaatacg gttgtcatta tgacctctaa cctcggttcc gatttgattc
    25741 aggaacgctt cggtgaactg gattatgcgc acatgaaaga gctggtgctc ggtgtggtaa
    25801 gccataactt ccgtccggaa ttcattaacc gtattgatga agtggtggtc ttccatccgc
    25861 tgggtgaaca gcacattgcc tcgattgcgc agattcagtt gaaacgtctg tacaaacgtc
    25921 tggaagaacg tggttatgaa atccacattt ctgacgaggc gctgaaactg ctgagcgaga
    25981 acggttacga tccagtctat ggtgcacgtc ctttgaaacg tgctatccag cagcagatcg
    26041 aaaacccgct ggcacagcaa atactgtctg gtgaattggt tccgggtaaa gtgattcgcc
    26101 tggaagttaa tgaagaccgg attgtcgccg tccagtaaat gataaaacga gcccttcggg
    26161 gctcgttttt gtctataagt tagacggaaa agactatatt taagatgttt tgcctgaaaa
    26221 atgagcgaac gataaagttt ttatattttt cgcttgtcag gccggaataa ctccctataa
    26281 tgcgccacca ctgacacgga acaacggcaa acacgccgcc gggtcagcgg ggttctcctg
    26341 agaattccgg cagagaaagc aaaaataaat gcttgactct gtagcgggaa agcgtattat
    26401 gcacaccccg cgccgctgag aaaaagcgaa gcggtactgc tctttaacaa tttatcagac
    26461 aatctgtgtg ggcactcgaa gatacggatt cttaacgtcg caagacgaaa aatgaatacc
    26521 aagtctcaag agtgaacacg taattcatta cgaagtttaa ttctttgagc atcaaacttt
    26581 taaattgaag agtttgatca tggctcagat tgaacgctgg cggcaggcct aacacatgca
    26641 agtcgaacgg taacaggaag cagcttgctg
//
LOCUS       DAPOAV010000059        26577 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.059, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000059 DAPOAV010000000
VERSION     DAPOAV010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26577
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.059"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            7..999
                     /gene="tehA"
                     /locus_tag="RN951_002836"
     CDS             7..999
                     /gene="tehA"
                     /locus_tag="RN951_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate transporter/tellurite-resistance
                     protein TehA"
                     /protein_id="HDX2527810.1"
                     /translation="MQSDKVLNLPAGYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGL
                     VILAMIIWGLLTSAFIARLIRFPHSVLAEVRHPVLSSFVSLFPATTMLVAIGFVPWFR
                     PLAVCLFSFGVVVQLAYAAWQTAGLWRGSHPEEATTPGLYLPTVANNFISAMACGALG
                     YTDAGLVFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSV
                     NGGEGDTLAKMLFGYGLLQLLFMLRLMPWYLSQPFNASFWSFSFGVSALATTGLHLGS
                     GSDNGFFHTLAVPLFIFTNFIIAILLIRTFALLMQGKLLVRTERAVLMKAEDKE"
     gene            996..1589
                     /gene="tehB"
                     /locus_tag="RN951_002837"
     CDS             996..1589
                     /gene="tehB"
                     /locus_tag="RN951_002837"
                     /EC_number="2.1.1.265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance methyltransferase TehB"
                     /protein_id="HDX2527811.1"
                     /translation="MIIRDENYFTDKYELTRTHSEVLEAVKVVKPGKTLDLGCGNGRN
                     SLYLAANGYDVDAWDKNAMSIANVERIKSIENLDNLHTRVVDLNNLTFDRQYDFILST
                     VVLMFLEAKTIPGLIANMQRCTKPGGYNLIVAAMDTADYPCTVGFPFAFKEGELRRYY
                     EGWERVKYNEDVGELHRTDANGNRIKLRFATMLARKK"
     gene            1891..2559
                     /locus_tag="RN951_002838"
     CDS             1891..2559
                     /locus_tag="RN951_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3313 domain-containing protein"
                     /protein_id="HDX2527812.1"
                     /translation="MRTTSFAKVAALCGLLALSGCASKITQPDKYSGFLNNYSDLKET
                     TSATGKPVLRWVDPSFDQSKYDSIVWNPITYYPVPKPSTQVGQKVLDKILNYTNTEMK
                     EAIAQRKPLVTTAGPRSLIFRGAITGVDTSKEGLQFYEVVPVALVVAGTQMATGHRTM
                     DTRLYFEGELIDAATNKPVIKVVRQGEGKDLNNESTPMAFENIKQVIDDMATDATMFD
                     VNKK"
     gene            complement(2577..3083)
                     /gene="tnpA"
                     /locus_tag="RN951_002839"
                     /pseudo
     CDS             complement(2577..3083)
                     /gene="tnpA"
                     /locus_tag="RN951_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604919.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            3091..4299
                     /locus_tag="RN951_002840"
     CDS             3091..4299
                     /locus_tag="RN951_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001458895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDX2527813.1"
                     /translation="MKRLQAFKFQLRPGGQQECEMRRFAGACRFVFNRALARQNENHE
                     AGNKYIPYGKMASWLVEWKNATETQWLKDSPSQPLQQSLKDLERAYKNFFRKRAAFPR
                     FKKRGQNDAFRYPQGVKLDQENSRIFLPTLGWMRYRNSRQVTGVVKNVTVSQSCGKWY
                     ISIQTESEVSTPVHPSASMVGLDAGVAKLATLSDGTVFEPVNSFQKNQKKLARLQRQL
                     SRKVKFSNNWQKQKRKIQRLHSCIANIRRDYLHKVTTAVSKNHAMIVIEDLKVSNMSK
                     SAAGTVSQPGRNVRAKSGLNRSILDQGWYEMRRQLAYKQLWRGGQVLAVPPAYTSQRC
                     AYCGHTAKENRLSQSKFRCQVCGYTANADVNGARNILAAGHAVLACGEMVQSGRPLKQ
                     EPTEMIQATA"
     gene            complement(4339..5553)
                     /gene="ydcO"
                     /locus_tag="RN951_002841"
     CDS             complement(4339..5553)
                     /gene="ydcO"
                     /locus_tag="RN951_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BenE family transporter YdcO"
                     /protein_id="HDX2527814.1"
                     /translation="MLRCLYAITHEVTMRLFSIPPPTLLAGFLAVLIGYASSAAIIWQ
                     AAIVAGATTAQISGWMTALGLAMGVSTLTLTLWYRVPVLTAWSTPGAALLVTGLQGLT
                     LNEAIGVFIVTNALIVLCGITGLFARLMRIIPHSLAAAMLAGILLRFGLQAFASLDGQ
                     FTLCGSMLLVWLATKAVAPRYAVIAAMIIGIVIVIAQGDVVTTDVVFKPVLPTYITPD
                     FSFAHSLSVALPLFLVTMASQNAPGIAAMKAAGYSAPVSPLIVFTGLLALVFSPFGVY
                     SVGIAAITAAICQSPEAHPDKDQRWLAAAVAGIFYLLAGLFGSAITGMMAALPVSWIQ
                     MLAGLALLSTIGGSLYQALHNERERDAAVVAFLVTASGLTLVGIGSAFWGLIAGGVCY
                     VVLNLIADRNRY"
     gene            5606..6142
                     /gene="sutR"
                     /locus_tag="RN951_002842"
     CDS             5606..6142
                     /gene="sutR"
                     /locus_tag="RN951_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SutR"
                     /protein_id="HDX2527815.1"
                     /translation="MENLARFLSTTLKQLRQQRGWSLSRLAEATGVSKAMLGQIERNE
                     SSPTVATLWKIATGLNVPFSTFISPPQSATPSVYDPQQQAMVITSLFPYDPQLCFEHF
                     SIQMASGAISESTPHEKGVIEHVVVIDGQLDLCVDGEWQTLNCGEGVRFAADVTHIYR
                     NGGEQTVHFHSLIHYPRS"
     gene            6215..8176
                     /gene="rlhA"
                     /locus_tag="RN951_002843"
     CDS             6215..8176
                     /gene="rlhA"
                     /locus_tag="RN951_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA 5-hydroxycytidine C2501 synthase"
                     /protein_id="HDX2527816.1"
                     /translation="MTVSSHRLELLSPARDAAIAREAILHGADAVYIGGPGFGARHNA
                     SNSLKDIAELVPFAHRYGAKIFVTLNTILHDDELEPAQRLITDLYQTGVDALIVQDMG
                     ILELDIPPIELHASTQCDIRTVEKAKFLSDVGFTQIVLARELNLDQIRAIHQATDATI
                     EFFIHGALCVAYSGQCYISHAQTGRSANRGDCSQACRLPYTLKDDQGRVVSYEKHLLS
                     MKDNDQTANLGALIDAGVRSFKIEGRYKDMSYVKNITAHYRQMLDAIIEERGDLARAS
                     SGRTEHFFVPSTEKTFHRGSTDYFVNARKGDIGAFDSPKFIGLPVGEVVKVAKDHLDV
                     AVTEPLANGDGLNVLIKREVVGFRANTVEKTGENQYRVWPNEMPADLHKIRPHHPLNR
                     NLDHNWQQALTKTSSERRVAVDIELGGWQEQLILTLTSEEGVSITHTLDGQFDEANNA
                     EKAMNNLKDGLAKLGQTLYYARDVQINLPGALFVPNSLLNQFRREAADMLDAARLASY
                     QRGSRKPVADPAPVYPQTHLSFLANVYNQKAREFYHRYGVQLIDAAYEAHEEKGEVPV
                     MITKHCLRFAFNLCPKQAKGNIKSWKATPMQLVNGDEVLTLKFDCRPCEMHVIGKIKN
                     HILKMPLPGSVVASVSPDELLKTLPKRKG"
     gene            complement(8268..8498)
                     /locus_tag="RN951_002844"
     CDS             complement(8268..8498)
                     /locus_tag="RN951_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncJ family protein"
                     /protein_id="HDX2527817.1"
                     /translation="MFTKALSVVLLTCALFSGQLMAGHKGHEFVWVKNVDHQLRHEAD
                     SDELRAVAEESAEGLREHFYWQKSRKPEAGQR"
     gene            8720..8896
                     /gene="hicA"
                     /locus_tag="RN951_002845"
     CDS             8720..8896
                     /gene="hicA"
                     /locus_tag="RN951_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415954.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin HicA"
                     /protein_id="HDX2527818.1"
                     /translation="MKQSEFRRWLESQGVDVANSSNHLKLRFHGRRSVMPRHPCDEIK
                     EPLRKAILKQLGLS"
     gene            8942..9358
                     /gene="hicB"
                     /locus_tag="RN951_002846"
     CDS             8942..9358
                     /gene="hicB"
                     /locus_tag="RN951_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HicB"
                     /protein_id="HDX2527819.1"
                     /translation="MRYPVTLTPAPEGGYMVSFVDIPEALTQGETVAEAMEAAKDALL
                     TAFDFYFEDNELIPLPSPLNSHDHFIEVPLSVASKVLLLNAFLQSEITQQELARRIGK
                     PKQEITRLFNLHHATKIDAVQLAAKALGKELSLVMV"
     gene            9437..10843
                     /locus_tag="RN951_002847"
     CDS             9437..10843
                     /locus_tag="RN951_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDX2527820.1"
                     /translation="MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVS
                     HAYQLLESQGYIIARPQSGYYVAPQAIKMPKAPVIPVTRDEAVDINTYIFDMLQASRD
                     PSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
                     QGITISPDEIVITAGALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSV
                     ATDVKEGIDLQALELALQEYPVKACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTL
                     IEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQR
                     LQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKI
                     HHNDSGYFLWLELPEPLDAGELSLAALTHHISIAPGKMFSTGENWSRFFRFNTAWQWG
                     EREEQAVKQLGKLIQERL"
     gene            11088..12233
                     /locus_tag="RN951_002848"
     CDS             11088..12233
                     /locus_tag="RN951_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDX2527821.1"
                     /translation="MSKTFARSSLCALSMTIMTAHAAEPPTNLDKPEGRLDIIAWPGY
                     IERGQTDKQYDWVTQFEKETGCAVNVKTAATSDEMVSLMTKGGYDLVTASGDASLRLI
                     MGKRVQPINTALIPNWKTLDPRVVKGDWFNVGGKVYGTPYQWGPNLLMYNTKTFPTPP
                     DSWQVVFVEQNLPDGKSNKGRVQAYDGPIYIADAALFVKATQPQLGISDPYQLTEEQY
                     QAVLKVLRAQHSLIHRYWHDTTVQMSDFKNEGVVASSAWPYQANALKAEGQPVATVFP
                     KEGVTGWADTTMLHSEAKHPVCAYKWMNWSLTPKVQGDVAAWFGSLPVVPEGCKASPL
                     LGEKGCETNGFNYFDKIAFWKTPIAEGGKFVPYSRWTQDYIAIMGGR"
     gene            12251..13264
                     /locus_tag="RN951_002849"
     CDS             12251..13264
                     /locus_tag="RN951_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX2527822.1"
                     /translation="MTYAVEFDNVSRLYGDVRAVDGVSIAIKDGEFFSMLGPSGSGKT
                     TCLRLIAGFEQLSGGAISIFGKPASNLPPWERDVNTVFQDYALFPHMSILDNVAYGLM
                     VKGVNKKQRHAMAQEALEKVALGFVHQRKPSQLSGGQRQRVAIARALVNEPRVLLLDE
                     PLGALDLKLREQMQLELKKLQQSLGITFIFVTHDQGEALSMSDRVAVFNNGRIEQVDS
                     PRDLYMRPRTPFVAGFVGTSNVFDGLMAEKLCGMTGSFALRPEHIRLNTPGELQANGT
                     IQAVQYQGAATRFELKLNGGEKLLVSQANMTGEELPATLTPGQQVMVSWSRDVMVPLV
                     EER"
     gene            13265..14206
                     /locus_tag="RN951_002850"
     CDS             13265..14206
                     /locus_tag="RN951_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX2527823.1"
                     /translation="MAMNVLQSPSRPGLGKVSGFFWHNPGLGLFLLLLGPLMWFGIVY
                     FGSLLTLLWQGFYTFDDFTMSVTPELTLANIRALFNPANYDIILRTLTMAVAVTIASA
                     ILAFPMAWYMARYTSGKMKAFFYIAVMLPMWASYIVKAYAWTLLLAKDGVAQWFLQHL
                     GLEPLLTAFLTLPAVGGNTLSTSGLGRFLVFLYIWLPFMILPVQAALERLPPSLLQAS
                     ADLGARPRQTFRYVVLPLAIPGIAAGSIFTFSLTLGDFIVPQLVGPPGYFIGNMVYSQ
                     QGAIGNMPMAAAFTLVPIILIALYLAFVKRLGAFDAL"
     gene            14196..14990
                     /locus_tag="RN951_002851"
     CDS             14196..14990
                     /locus_tag="RN951_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX2527824.1"
                     /translation="MHSERAPFFLKLAAWGGVVFLHFPILIIAAYAFNTEDAAFSFPP
                     QGLTLRWFSVAAQRSDILDAVTLSLKVAALATLIALVLGTLAAAALWRRDFFGKNAIS
                     LLLLLPIALPGIVTGLALLTAFKTINLEPGFFTIVVGHATFCVVVVFNNVIARFRRTS
                     WSLVEASMDLGANGWQTFRYVVLPNLSSALLAGGMLAFALSFDEIIVTTFTAGHERTL
                     PLWLLNQLGRPRDVPVTNVVALLVMLVTTLPILGAWWLTREGDNGQ"
     gene            15012..16436
                     /gene="patD"
                     /locus_tag="RN951_002852"
     CDS             15012..16436
                     /gene="patD"
                     /locus_tag="RN951_002852"
                     /EC_number="1.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminobutyraldehyde dehydrogenase"
                     /protein_id="HDX2527825.1"
                     /translation="MQHKLLINGELVSGEGEKQPVYNPATGDVLLEIAEASAEQVDAA
                     VRAADAAFAEWGQTTPKVRAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIP
                     AIVDVFRFFAGAARCLNGLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLA
                     PALAAGNCVVLKPSEITPLTALKLAELAKDIFPAGVINILFGRGKTVGDPLTGHPKVR
                     MVSLTGSIATGEHIISHTASSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNA
                     GQDCTAACRIYAQKGIYDTLVEKLGAAVATLKSGAPDDESTELGPLSSLAHLERVSKA
                     VEEAKATGHIKVITGGEKRKGNGYYYAPTLLAGALQDDAIVQKEVFGPVVSVTPFDNE
                     EQVVNWANDSQYGLASSVWTKDVGRAHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLS
                     GYGKDMSLYGLEDYTVVRHVMVKH"
     gene            complement(16533..16628)
                     /gene="yncL"
                     /locus_tag="RN951_002853"
     CDS             complement(16533..16628)
                     /gene="yncL"
                     /locus_tag="RN951_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response membrane protein YncL"
                     /protein_id="HDX2527826.1"
                     /translation="MNVSSRTVVLINFFAAVGLFTLISMRFGWFI"
     gene            16823..16996
                     /gene="ortT"
                     /locus_tag="RN951_002854"
     CDS             16823..16996
                     /gene="ortT"
                     /locus_tag="RN951_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415962.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orphan toxin OrtT"
                     /protein_id="HDX2527827.1"
                     /translation="MSLYQHMLVFYAVMAAIAFLITWFLSHDKKRIRFLSAFLVGATW
                     PMSFPVALLFSLF"
     gene            17082..17315
                     /locus_tag="RN951_002855"
     CDS             17082..17315
                     /locus_tag="RN951_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcY family protein"
                     /protein_id="HDX2527828.1"
                     /translation="MSHLDEVIARVDAAIEESVIAHMNELLIALSDDAELSREDRYTQ
                     QQRLRTAIAHHGRKHKEDMEARHEQLTKGGTIL"
     gene            complement(17316..17765)
                     /locus_tag="RN951_002856"
     CDS             complement(17316..17765)
                     /locus_tag="RN951_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDX2527829.1"
                     /translation="MNQSLTLAFLIAAGIGLVVQNTLMVRITQTSSTILIAMLLNSLV
                     GIVLFVSILWFKQGMAGFGELVSSVRWWTLIPGLLGSFFVFASISGYQNVGAATTIAV
                     LVASQLIGGLMLDIFRSHGVPLRALFGPICGAILLVVGAWLVARRSF"
     gene            complement(17762..18280)
                     /gene="mddA"
                     /locus_tag="RN951_002857"
     CDS             complement(17762..18280)
                     /gene="mddA"
                     /locus_tag="RN951_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine sulfoximine/L-methionine sulfone
                     acetyltransferase"
                     /protein_id="HDX2527830.1"
                     /translation="MSIRFARKADCAAIAEIYNHAVLYTAAIWNDQTVDADNRIAWFE
                     ARTLAGYPVLVSEENGVVTGYASFGDWRSFDGFRHTVEHSVYVHPDHQGKGLGRKLLS
                     RLIDEARDCGKHVMVAGIESQNQASLHLHQSLGFVVTAQMPQVGTKFGRWLDLTFMQL
                     QLDERTEPDAIG"
     gene            18461..19498
                     /gene="curA"
                     /locus_tag="RN951_002858"
     CDS             18461..19498
                     /gene="curA"
                     /locus_tag="RN951_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415966.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent curcumin/dihydrocurcumin
                     reductase"
                     /protein_id="HDX2527831.1"
                     /translation="MGQQKQRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLR
                     TVYLSLDPYMRGRMSDEPSYSPPVDIGGVMVGGTVSRVVESNHPDYQSGDWVLGYSGW
                     QDYDISSGDDLVKLGDHPQNPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATG
                     PVGATVGQIGKLKGCRVVGVAGGAEKCRHATEVLGFDVCLDHHADDFAEQLAKACPKG
                     IDIYYENVGGKVFDAVLPLLNTSARIPVCGLVSSYNATELPPGPDRLPLLMATVLKKR
                     IRLQGFIIAQDYGHRIHEFQREMGQWVKEDKIHYREEITDGLENAPQTFIGLLKGKNF
                     GKVVIRVAGDD"
     gene            19696..20361
                     /gene="mcbR"
                     /locus_tag="RN951_002859"
     CDS             19696..20361
                     /gene="mcbR"
                     /locus_tag="RN951_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415967.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid/biofilm transcriptional regulator
                     McbR"
                     /protein_id="HDX2527832.1"
                     /translation="MPGTGKMKHVSLTLQVENDLKHQLSIGALKPGARLITKNLAEQL
                     GMSITPVREALLRLVSVNALSVAPAQAFTVPEVGKRQLDEINRIRYELELMAVALAVE
                     NLTPQDLAELQELLEKLQQAQEKGDMEQIINVNRLFRLAIYHRSNMPILCEMIEQLWV
                     RMGPGLYYLYEAINPAELREHIENYHLLLAALKAKDKEGCRHCLAEIMQQNIAILYQQ
                     YYR"
     gene            complement(20397..22499)
                     /locus_tag="RN951_002860"
     CDS             complement(20397..22499)
                     /locus_tag="RN951_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HDX2527833.1"
                     /translation="MKIFSVRQTVLPALLVLSPVVFAADEQTMIVSAAPQVVSELDTP
                     AAVSVVDGEEMRLATPRINLSESLTGVPGLQVQNRQNYAQDLQLSIRGFGSRSTYGIR
                     GIRLYVDGIPATMPDGQGQTSNIDLSSVQNVEVLRGPFSALYGNASGGVMNVTTQTGQ
                     QPPTIEASSYYGSFGSWRYGLKATGATGDGTQPGDVDYTVSTTRFTTHGYRDHSGAQK
                     NLANAKLGVRIDEASKLSLIFNSVDIKADDPGGLTKAEWKANPQQAPRAEQYDTRKTI
                     KQTQAGLRYERSLSSRDDMSVMMYAGERETTQYQSIPMAPQLNPSHAGGVITLQRHYQ
                     GIDSRWTHRGELGVPVTFTTGLNYENMSENRKGYNNFRLNSGMPEYGQKGELRRDERN
                     LMWNIDPYLQTQWQLSEKLSLDAGVRYSSVWFDSNDHYVTPGNGDDSGDASYHKWLPA
                     GSLKYAMTDAWNIYLAAGRGFETPTINELSYRADGQSGMNLGLKPSTNDTIEIGSKTR
                     IGDGLLSLALFQTDTDDEIVVDSSSGGRTTYKNAGKTRRQGAELAWDQRFAGDFRVNA
                     SWTWLDATYRSNVCNEQDCNGNRMPGIARNMGFASIGYVPEDGWYAGTEARYMGDIMA
                     DDENTAKAPSYTLVGLFTGYKYNYHNLTVDLFGRVDNLFDKEYVGSVIVNESNGRYYE
                     PSPGRNYGVGMNIAWRFE"
     gene            22741..23802
                     /locus_tag="RN951_002861"
     CDS             22741..23802
                     /locus_tag="RN951_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HDX2527834.1"
                     /translation="MHLRHLFSSRLRGSLLLGSLLVVSSFSTQAAEEMLRKAVGKGAY
                     EMAYSQQENALWLATSQSRKLDKGGVVYRLDPVTLEVTQAIHNDLKPFGATINNTTQT
                     LWFGNTVNSAVTAIDAKTGEVKGRLVLDDRKRTEEVRPLQPRELVADDATNTVYISGI
                     GKESVIWVVDGGNIKLKTAIQNTGKMSTGLALDSEGKRLYTTNADGELITIDTADNKI
                     LSRKKLLDDGKEHFFINISLDTARQRAFITDSKAAEVLVVDTRNGNILAKVAAPESLA
                     VLFNPARNEAYVTHRQAGKVSVIDAKSYKVVKTFDTPTHPNSLALSADGKTLYVSVKQ
                     KSTKQQEATQPDDVIRIAL"
     gene            complement(23915..25414)
                     /gene="ansP"
                     /locus_tag="RN951_002862"
     CDS             complement(23915..25414)
                     /gene="ansP"
                     /locus_tag="RN951_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310084.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparagine permease"
                     /protein_id="HDX2527835.1"
                     /translation="MSKHDTDTSDQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAI
                     GTGLFLGAGARLQMAGPALALVYLICGLFSFFILRALGELVLHRPSSGSFVSYAREFL
                     GEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWGAFGGVPQWVFALAALTIVGTMNM
                     IGVKWFAEMEFWFALIKVLAIVTFLVVGTVFLGSGQPLDGNTTGFHLITDNGGFFPHG
                     LLPALVLIQGVVFAFASIEMVGTAAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLV
                     MLLPWSAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMA
                     MGGSAPSFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIAS
                     WAFIIVCQMRLRKAIKEGKAADVSFKLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYT
                     IAALPIIGILLVIGWFGVRKRVAEIHSTAPVVEEDEEKQEIVFKPETAS"
     gene            25681..26298
                     /locus_tag="RN951_002863"
     CDS             25681..26298
                     /locus_tag="RN951_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HDX2527836.1"
                     /translation="MIKVYGVPGWGSTISELMLTLADIPYQFVDVSGFDHEGASRELL
                     KTLNPLCQVPTLALENDEIMTETAAIALMVLDRRPDLAPPVGRAERQLFQRLLVWLVA
                     NVYPTFTFADYPERWAPDAPEQLKKNVIEYRKSLYIWLNSQLTAEPYAFGEQLTLVDC
                     YLCTMRTWGPGHEWFQDNATNISAIADAVCQLPKLQEVLKRNEII"
     gene            26374..>26577
                     /locus_tag="RN951_002864"
     CDS             26374..>26577
                     /locus_tag="RN951_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5445 family protein"
                     /protein_id="HDX2527837.1"
                     /translation="MVCFLIYITLLFIQRVYFISSEKKLTIHIVQMFQLLSQAFYNLK
                     MFLMMDMLGVGDAININTNKNIRQ"
BASE COUNT         6786 a         6446 c         6810 g         6535 t
ORIGIN      
        1 aagaagatgc agagcgataa agtgctcaat ttgccggcag gctactttgg tattgtgttg
       61 gggacgatag ggatgggatt tgcctggcgc tatgccagcc aggtttggca ggtcagccac
      121 tggttagggg atgggctggt gattctggcg atgatcatct ggggattatt gactagcgca
      181 tttattgccc gactcatacg ctttccgcat agcgtgctgg cggaagttcg ccatccagtg
      241 ctgagcagtt ttgtgagttt gtttccggca acgacgatgc tggtggcgat tggttttgtt
      301 ccgtggtttc gcccactggc ggtgtgcctg ttcagttttg gtgtcgtggt tcagttggct
      361 tatgccgcct ggcaaactgc gggattatgg cgcggatctc accctgaaga agctaccacg
      421 cctggactgt atctgccgac agttgccaac aactttatca gcgcaatggc ctgtggtgcg
      481 ttgggctaca ccgacgccgg tctggtgttt ttaggcgcag gcgttttctc atggctaagc
      541 cttgaaccgg tgatcttgca gcgtctgcgc agttcgggag aattacccac ggcactgcgg
      601 acatcactcg gcattcagct cgctcctgcg ctggtggctt gtagtgcctg gctgagcgtc
      661 aacggcggcg agggtgacac gctggcgaaa atgcttttcg gttatggact gctgcaactg
      721 ctgtttatgc tacgtctgat gccatggtat ctctcccagc catttaatgc ttcattctgg
      781 agtttctcgt tcggcgtatc tgcactggca accaccggtt tgcatctggg gagtggcagc
      841 gataatggat ttttccatac gctggcggtg ccgctgttta tctttaccaa ttttattatt
      901 gcaatactgc tcatccgtac ttttgcgctt ctgatgcagg gaaaattgtt agtcagaacc
      961 gagcgcgccg ttttaatgaa agcagaggac aaagaatgat cattcgtgac gaaaactatt
     1021 ttactgataa atatgaatta acccgcacac actctgaagt actggaagcg gtgaaagtgg
     1081 ttaaaccggg taaaacgctg gatctgggct gtggcaatgg tcgtaacagt ctttacctgg
     1141 cagccaatgg ttatgatgtt gacgcatggg ataaaaatgc catgagtatc gccaacgtcg
     1201 agcgcattaa atccattgaa aatctggata atttacacac ccgagtcgtt gatctgaata
     1261 acctcacatt tgatagacag tacgatttta ttctttcgac tgtggtgctg atgttccttg
     1321 aggctaaaac catccccggg ttgattgcca atatgcaacg ttgcactaaa cctggtggtt
     1381 acaacctgat tgtggcggcg atggataccg ctgattatcc atgtaccgtc ggcttcccgt
     1441 ttgccttcaa agagggagaa ttacgtcgat attacgaagg ctgggagagg gtgaaataca
     1501 atgaagacgt cggcgagctg caccgcaccg acgccaacgg taatcgtatt aaactgcgtt
     1561 tcgccacgat gctggcacgt aaaaaatgac ccggtaagca caaaacgcgt gaaaattccc
     1621 cacgctgaga tgatttactg ttcttctttt cggtaagcat attttttatc gaagggatgt
     1681 gaaattaatc acagtagtcg aagtttttag cagcttaact tactgaaatt taagtactga
     1741 tgattgactt agcccctttt tcggcattga ctatgtcgtc tgaaaagggg ctgaaaaatt
     1801 tattttcacc aacacttttt ttgccacaac acgaagcggc gctttttgct ataacttaga
     1861 aagtaatata atcatctcag gaaactattc atgcgtacca catcatttgc gaaagttgca
     1921 gctttatgcg gcttattggc tctgtctggt tgtgcctcta aaatcaccca gccagataaa
     1981 tattctggtt ttttaaacaa ttactctgat ttaaaagaaa caacctcggc tacaggtaaa
     2041 cctgttttac gttgggtaga cccgagtttt gatcaaagca aatatgacag catcgtctgg
     2101 aacccaatca cttattatcc ggtaccgaaa ccgtcgaccc aggtagggca gaaagttctg
     2161 gataaaattt tgaactatac caacaccgaa atgaaagaag cgatagcgca gcgtaaacca
     2221 ctggttacca ccgctgggcc gcgtagtctg attttccgtg gggccattac cggtgtagat
     2281 accagcaaag aagggctgca attctatgaa gtggttcctg ttgcattagt ggttgcgggg
     2341 acgcaaatgg ctacaggcca ccgtaccatg gatactcgcc tctattttga aggtgagctg
     2401 attgatgcag cgactaataa accggttatc aaagtcgttc gtcagggcga aggtaaagac
     2461 ctgaataacg aaagtacgcc aatggctttc gaaaatatta aacaagttat tgatgacatg
     2521 gcgaccgatg ccaccatgtt tgacgttaac aaaaagtagt tccagacgcg ccatcgttag
     2581 atggcgcttt ttatccggtg cgccgtaaaa ccccatcctt cagggcgggg atataaggcg
     2641 cggttttcca cctgaccagg tgtttgctgt tgttcaatgt attggcggat gacggatatt
     2701 ggcgcacctc cgcagctact ggcaaaatag ccaggactcc acaaaacgcc tttgtagtaa
     2761 tacctgaatg caatatctgg tcgatctcgt cgcagtcacc tacccgatac gcctttgagg
     2821 ctgtttacca gactggatat cgccagtttg ggaggatagt taattaacaa atggacgtga
     2881 tctggttcgc catccatttc aaccagttca gcttcaaaat cagcacatac atttgaaaag
     2941 taagtgcgta gtttttctgt cgcgtcatgg tcaaaaatct ggcgtcggta tctggtgaca
     3001 aagagcaggt gaacatgcat caggaaaaca caatgccttc cacgccggat atcggtttct
     3061 tttttcacag accaaagtat catttgacct gtgaaacgat tacaggcatt taaattccag
     3121 ttaagacccg gtggtcaaca ggagtgtgaa atgaggcgct tcgcaggcgc atgtcgtttc
     3181 gttttcaatc gtgctctggc acgtcagaat gagaatcatg aggccggtaa taaatacatc
     3241 ccttacggga aaatggcttc ctggctggtt gagtggaaaa atgccactga aacgcaatgg
     3301 cttaaagatt ctccctcaca gccattgcaa cagtcactga aagaccttga gcgggcttac
     3361 aaaaacttct tccggaagcg ggctgctttt ccccgattca aaaagcgggg acagaatgat
     3421 gcattccgct acccgcaggg cgttaagctc gatcaggaaa acagccgtat ttttctgccg
     3481 acactgggct ggatgcgcta ccggaacagc cgtcaggtca cgggtgttgt gaaaaatgtc
     3541 actgtcagcc agtcctgcgg taagtggtac atcagtattc agacagaaag tgaagtatca
     3601 actccggttc acccttcagc atcaatggtc gggctggatg ctggcgtggc taaactcgcc
     3661 acgctgtcag atggcacagt ctttgagcct gtaaacagtt ttcagaaaaa ccagaagaag
     3721 ctggcgagac ttcagcgaca gttaagccgc aaggtcaaat tcagcaacaa ctggcaaaag
     3781 cagaaacgca aaatacagcg actgcattcc tgtatcgcaa atatccgcag ggactacctt
     3841 cacaaagtca caacggccgt cagcaaaaac cacgcaatga tagtcattga ggatttgaag
     3901 gtcagcaaca tgtcaaagtc agcagcgggt acggtcagcc agccggggcg caatgtccgg
     3961 gcaaaatcag gtttaaaccg ttcgatactg gatcagggct ggtatgaaat gcgccgccag
     4021 cttgcgtaca agcagctctg gcgtggcggt caggtgcttg ctgttccgcc agcgtataca
     4081 agccagcgtt gcgcgtactg tggtcataca gcgaaagaga accgcctgtc acaaagtaaa
     4141 ttcagatgcc aggtatgtgg atatacagcg aacgccgatg taaatggcgc tcgcaacatt
     4201 ttagcggcgg ggcacgccgt tcttgcctgt ggagagatgg tgcagtcagg ccgcccgttg
     4261 aagcaggaac ccaccgaaat gattcaggcg acagcctgaa cgtagcaggg atccacgtcc
     4321 ttcagggcgt ggaggatgtc aatatcggtt tctgtcagcg attaaattca acaccacgta
     4381 acaaacgcct ccggcaatta atccccaaaa cgcagaacca atcccgacca gcgtcaatcc
     4441 acttgccgtt accagaaatg ccaccaccgc cgcgtctcgc tcacgctcat tatgcagcgc
     4501 ctgatacaaa ctgccgccga tggtacttaa cagcgccaga cctgccagca tctggatcca
     4561 acttacgggc agggcagcca tcatcccggt aatggcacta ccaaacagac ctgcgagcaa
     4621 atagaaaatg cctgcaacgg cagcggccag ccaacgttga tctttatccg gatgcgcttc
     4681 cgggctttgg caaatagccg cggtgattgc cgcaataccg acggaataaa cgccgaaagg
     4741 ggaaaaaacc agtgccagca atccagtaaa tacaattaat ggcgaaacag gagccgaata
     4801 tccagctgct ttcattgctg cgatacccgg tgcgttttgc gatgccatcg tcaccagaaa
     4861 aagggggagt gcaacgctca ggctgtgagc aaacgaaaaa tcaggggtaa tataagtggg
     4921 gagaacgggt ttaaagacaa catcagttgt gacaacgtca ccttgcgcga tgacgatcac
     4981 gatcccaata atcatcgcgg caattaccgc atagcgcggc gcaacggcct tggttgccag
     5041 ccataccagc aacatacttc cacacaacgt aaattgaccg tccagactgg caaacgcctg
     5101 taaaccaaag cgtaataaaa tcccggcaag cattgccgcc gcaagcgagt gcggaataat
     5161 gcgcatcaga cgagcaaaga gtcccgttat gccgcagagg actattagcg cgttggtgac
     5221 aataaaaacg ccgatggctt cgttaagtgt tagtccctgc aatccggtga ccaacaaagc
     5281 cgcgccaggc gttgaccatg cggtgagaac aggtacgcga taccataatg tcagagtcag
     5341 cgtactgacg cccattgcca gccccagcgc cgtcatccag ccagagattt gtgcagtggt
     5401 ggctccggcg acaatcgctg cttgccagat tattgccgct gaactggcgt agccaattaa
     5461 taccgccaga aaccccgcca gtagcgtggg tggaggaata gaaaacagac gcatagtcac
     5521 ctcgtgcgtt atagcgtaca ggcaccgtag catttgtccg ttataacgca caagtgataa
     5581 acttccgttt tgccggagga gtcgcatgga aaatctcgct cgctttttat ccaccacact
     5641 taaacaacta cgccagcagc gcggctggag tctttcgcga ctggcagaag cgacgggcgt
     5701 ttctaaagca atgttagggc agattgagcg taatgagtcc agtccgacgg tcgcgacatt
     5761 atggaaaatt gccaccgggt tgaacgtacc attttcaaca tttatttctc cgccgcagtc
     5821 cgctacgcct tcagtttatg atccacaaca gcaggcgatg gtgatcactt cgctgtttcc
     5881 ttatgatcca caactctgct ttgaacactt ctcgattcag atggcatctg gtgcaataag
     5941 cgaatcgacg ccccatgaga agggggtaat cgaacatgtc gtcgtcattg atggacaact
     6001 tgatctgtgc gttgatgggg aatggcagac ccttaattgt ggggaaggcg ttcgatttgc
     6061 tgcagacgtc acgcatatct atcgtaatgg tggggagcaa accgtacatt ttcattccct
     6121 catccattac ccgcgcagtt aagcgggaaa actatttcgc aacgtcgcgc ttgtggctaa
     6181 aatagccgcc atttttcagc tactggataa gaatgtgacc gtatcttctc atcgacttga
     6241 actgttaagc ccggcacgcg atgccgccat tgcccgcgaa gctattttgc acggtgccga
     6301 tgctgtttat atcggcggcc ctggttttgg tgcccgtcat aatgccagta atagcttgaa
     6361 agatattgcc gagctggtgc cgtttgccca tcgttatggt gcaaaaattt tcgtcacgct
     6421 taacaccatt ttgcatgatg atgagctgga acccgcgcaa cggctgatta ctgacctcta
     6481 ccagaccggt gtcgatgcgc tgattgttca ggatatgggg attctggaac ttgatattcc
     6541 gccgattgaa ctgcacgcca gtacgcagtg cgacattcgt acagttgaaa aagcgaagtt
     6601 cctctctgat gttggcttca cgcagattgt gctggcgcga gagctgaatc ttgatcagat
     6661 ccgcgcgatt caccaggcta cggacgcgac cattgaattc tttattcatg gggcactgtg
     6721 cgtggcctat tcgggtcagt gctacatttc tcatgcgcaa acagggcgta gcgccaaccg
     6781 tggcgattgc tcgcaggcgt gccgtttgcc atacacattg aaagacgatc aggggcgggt
     6841 ggtttcctat gaaaaacatc tgctgtcgat gaaagataac gatcagactg ccaacctcgg
     6901 cgcgctgatt gatgctggtg tacgctcctt caagattgaa gggcgttaca aagatatgag
     6961 ctacgtgaag aatatcaccg cccattatcg ccagatgctt gatgccatta ttgaagaacg
     7021 tggcgatctg gcgcgcgctt catcaggtcg tactgaacat ttctttgttc catcgacgga
     7081 aaagactttc caccgtggta gcacagatta ttttgtgaat gcccgtaaag gcgatattgg
     7141 cgcgttcgat tcgccgaaat ttatcggcct gccggtaggc gaagtagtga aagtggcgaa
     7201 agatcatctc gatgttgccg ttaccgagcc actggcaaat ggcgatggcc tgaacgtgtt
     7261 gattaaacgt gaagtcgtcg gttttcgtgc caatacggtc gagaaaaccg gagaaaatca
     7321 gtaccgcgtc tggcccaatg aaatgccagc agatttgcac aaaattcgtc cacatcaccc
     7381 actaaaccgt aatcttgatc ataactggca gcaggcactg acaaaaacct ccagcgaacg
     7441 tcgggtggcg gtagacattg aactgggcgg ctggcaggaa caactgattc tgaccctcac
     7501 cagtgaagag ggtgtcagca tcacgcatac gctggacggg cagttcgacg aagccaataa
     7561 cgccgaaaaa gcaatgaaca atctgaagga tggtctggca aaactggggc aaaccctcta
     7621 ttacgcccgc gatgtgcaaa ttaatttgcc gggggcgctg tttgtaccaa acagtctgtt
     7681 aaaccagttc cgccgtgaag ctgctgacat gctggatgct gcgcgtcttg ccagttacca
     7741 gcgcggcagc cgtaaaccgg ttgctgatcc tgcgccggtt tatccgcaaa cgcatctgag
     7801 tttcctcgcg aacgtataca accagaaagc gcgtgaattt tatcatcgct atggtgtgca
     7861 gctgattgac gcggcgtatg aagcacatga agagaagggc gaagtcccgg tgatgatcac
     7921 caagcattgt ctgcgctttg cctttaatct gtgcccgaaa caggcgaaag gcaatatcaa
     7981 aagctggaag gcgacgccaa tgcaactggt taacggcgat gaagtattaa cgctaaagtt
     8041 tgattgccgc ccatgcgaga tgcacgtcat tggcaaaatc aaaaatcaca tactgaaaat
     8101 gccgttaccg ggaagcgtag tggcatccgt aagtccggat gagctgctga aaacattgcc
     8161 gaagcgaaaa gggtaaaacg ccagttttct ggttactcac aacttattga atctgcatga
     8221 tattgcctgc cgggtaaggc gttacgccgc atccggcatc aaatgactca acgttgtccc
     8281 gcttctggtt tgcgcgattt ttgccagtaa aaatgctcgc gcaaaccttc cgccgactct
     8341 tccgccacag cacgcaattc atcgctgtcc gcttcatgac gcagctgatg atccacattc
     8401 tttacccaca caaattcatg tcctttgtgc cctgccatga gttgtcctga aaacagagca
     8461 cacgttaata agacaaccga taacgccttc gtaaacatcc tgccaccttt ttcttacctt
     8521 ttgccgctat gatgccgatc gtttcttgag gttattattc agttttgcaa attagcgcaa
     8581 agaaattctg gaatcttcct tcctgatttt gcattgcatt ctgccgttgc ggcgatttag
     8641 tgctattttc gagcaaatta cacacggagg taaacactaa tgtttacttt gttgatatac
     8701 tcagcggcag ggaggcgatg tgaaacaaag cgagttcaga cgttggctcg aatctcaggg
     8761 cgtcgatgta gcgaatagca gcaaccattt gaaactcagg tttcatggga ggcgcagtgt
     8821 catgccgcgt cacccctgcg atgagattaa agaaccattg cgtaaagcaa tcctgaaaca
     8881 actcggtttg agttaatcgc caattaaaaa ggttaatgac atgcgagaga cagtcgaaat
     8941 tatgcgttat cccgtcactc ttacacccgc gccggaaggc ggttatatgg tttcttttgt
     9001 ggatatccct gaagcgttga cccagggcga aactgtcgct gaagcgatgg aagcggcaaa
     9061 agatgcttta ctgaccgcat ttgattttta ttttgaagat aacgagctta tccctttacc
     9121 ttcgccatta aatagtcacg atcactttat tgaagtacct ttgagcgtcg cctctaaggt
     9181 attgctgtta aatgcttttt tacagtcaga aatcactcag caagagttag ccaggcgaat
     9241 tggcaaacct aaacaggaga ttactcgcct atttaacttg catcatgcga caaaaatcga
     9301 cgccgtccag ctcgcggcaa aggcgcttgg caaagagtta tcgctggtga tggtttaatt
     9361 acagttaacg aaaagttgtc atttttaaca actgatatag actgccgaat catctgcaca
     9421 taattacgat tcgataatga aaaaatacca gcagcttgca gaacaattac gcgagcagat
     9481 tgcgtcgggt atctggcaac ccggcgatcg tttgccttcg ttgcgtgacc aggtggcgct
     9541 ttcaggcatg agctttatga ctgtcagcca tgcctatcag ttgctcgaaa gtcagggata
     9601 tattatcgca cgaccgcagt cgggttatta cgttgcgcca caggcaataa aaatgccgaa
     9661 agcgccagtc attccagtca ctcgagatga agcagtcgat atcaacactt atatttttga
     9721 tatgttgcag gccagtcgcg atccgtcggt cgttccgttt gcctcggcct ttcccgaccc
     9781 gcgacttttc cccctccaac aactaaaccg ctcgctggcg caggtaagca aaaccgccac
     9841 agcgatgagc gtgattgaaa acttaccgcc aggaaacgca gaactgcgtc aggctattgc
     9901 tcgtcgctat gccttacagg gcatcaccat ttctcctgat gaaattgtca ttactgccgg
     9961 ggcgttagag gcattaaacc tcagtttgca agcggtaact gaaccgggcg attgggtgat
    10021 agtagagaat ccttgtttct acggtgcgtt gcaggcgctg gagcggctac ggctgaaggc
    10081 gttatcggtg gcgacggatg ttaaagaagg gatagatctt caggcgctgg aactggcgtt
    10141 gcaggagtat ccggtgaaag cgtgctggct gatgactaat agccagaatc cactcggatt
    10201 taccttaacg ccgcaaaaaa aagcacaact ggtggcgttg ctcaatcagt acaacgtaac
    10261 gctgattgaa gatgacgttt acagcgaact ttattttgga cgggaaaaac cgctgcctgc
    10321 gaaagcgtgg gatcgccacg atggcgtttt gcattgctct tcgttttcga aatgtctggt
    10381 gcctggtttt cgtattggtt gggtcgccgc cggaaaacat gcacgtaaaa ttcaacgctt
    10441 gcagttgatg agtacgcttt ccaccagctc accgatgcaa cttgcgctgg tggattacct
    10501 ttccacgcgc cgatacgacg cccatcttcg tcgcctgcgt cgccagcttg cggaacgtaa
    10561 acaacgtgcc tggcaggcac tgctgcgtta tctgcctgcg gaagtgaaaa ttcatcataa
    10621 tgacagtggt tactttctct ggttggagct ccccgagccg ttagatgccg gcgaattaag
    10681 cctggcggca ctgacgcatc atatcagtat tgcgccgggt aaaatgtttt ctaccggtga
    10741 aaactggtca cgttttttcc gttttaatac cgcgtggcag tggggagagc gtgaagaaca
    10801 ggcggtaaaa caattaggca aacttattca agaacggctg taatagcgtt taatttaatt
    10861 cctcttagat tgggtaatat gaatttcgaa tagcagtcat atttcctaac tccttgacta
    10921 tactccagaa gataacctta cagacggcat aatgcgcggt agctcacaac ctgaataaat
    10981 tttctcaggg gcgaaggtgt gcctgcaagc cgccgtctat ggttaaacaa ggagatattt
    11041 ttacggcacg gcggctgaac aattaattac gacaggagta agaccttatg agcaagacat
    11101 ttgcccgcag cagcctgtgt gcgctcagca tgacaataat gaccgctcac gccgccgaac
    11161 cgcctaccaa tttagataaa ccggaagggc gactggatat tatcgcctgg ccgggataca
    11221 tcgaacgcgg acaaactgat aaacaatacg actgggtaac gcagttcgaa aaagagacag
    11281 gctgcgcggt gaatgtgaaa accgccgcga cttccgatga aatggtcagt ctgatgacca
    11341 aagggggtta cgatctggtt acggcatccg gcgatgcctc gctgcgtttg attatgggta
    11401 aacgcgtgca gccgattaat accgcattga ttcccaactg gaaaacgctc gatccgcgcg
    11461 tggttaaagg cgactggttt aatgttggcg gcaaagttta cggcacacct taccaatggg
    11521 ggccgaacct gctgatgtac aacactaaaa ccttcccgac gccgccggat agctggcaag
    11581 tggtttttgt tgagcaaaat ctgccggacg gcaagagcaa taaaggccgc gttcaggctt
    11641 atgatggccc tatctatatt gcggacgctg cgttgttcgt taaagccact cagccgcagt
    11701 tgggcatcag cgatccgtat caactcaccg aagaacagta ccaggcggtg ctgaaagtgc
    11761 tgcgcgctca acacagtttg atccatcgct actggcatga cactaccgtg caaatgagcg
    11821 atttcaaaaa cgagggtgtg gttgcttcca gtgcctggcc ctatcaggcc aacgccctga
    11881 aagccgaagg ccagcctgtt gctaccgttt tcccgaagga gggtgttacc ggttgggctg
    11941 ataccaccat gctgcatagc gaagcgaaac atccggtttg cgcctacaaa tggatgaact
    12001 ggtcattaac gccaaaagtg cagggcgatg tggcggcctg gtttggctcg ttaccggtag
    12061 tgccggaagg gtgtaaagcc agtccgttat taggcgaaaa aggttgtgaa accaacggtt
    12121 ttaactattt cgacaaaatc gccttctgga aaacgcctat agcagaaggg ggcaagtttg
    12181 ttccctacag tcgctggacg caggattaca ttgccattat gggcggtcgc taacttcgct
    12241 ggggtgcttt atgacgtacg cagtggagtt tgacaacgtc tcgcggttgt acggtgacgt
    12301 gcgcgcagta gatggcgtca gtattgcgat aaaagatggt gagttcttct ctatgctggg
    12361 gccgtccggc tccggcaaaa ccacctgcct gcgcctgatt gctggcttcg aacagctttc
    12421 cggcggggct atctctatct ttggtaaacc cgccagcaat ctgccaccgt gggagcggga
    12481 cgtgaatact gtctttcagg actacgcgct atttccgcat atgtcgattc ttgacaatgt
    12541 cgcctatggg ctgatggtca aaggcgtgaa taaaaagcag cggcacgcaa tggcgcaaga
    12601 ggcgctggag aaagtggcgt tggggtttgt acatcaacgt aaaccgtcac aactttctgg
    12661 tggtcagcgc cagcgggttg ctatcgccag agcattggtg aatgaaccgc gcgtattgct
    12721 gttggatgaa ccgctcggcg cactggatct caaattgcgt gagcagatgc agctggaact
    12781 gaaaaaactg caacagtctc tcggtatcac ttttatcttc gttacccacg atcagggcga
    12841 agcgttatcg atgtccgatc gtgtggcggt tttcaataat ggacgcattg agcaggtcga
    12901 ttccccgcgc gatctctata tgcgcccgcg cacgccgttt gttgccgggt tcgttggtac
    12961 atcgaatgtt tttgatggac tgatggcaga gaaactttgt ggcatgacgg gaagcttcgc
    13021 cctgcgaccg gaacatatcc gcctcaacac ccctggtgaa ctgcaggcca atggcacgat
    13081 ccaggcggtg caatatcagg gcgcggcaac tcgttttgaa ctgaaattga acggcggtga
    13141 aaaactgctt gtgagtcagg ccaatatgac aggcgaagaa ctgcctgcca cgctcacgcc
    13201 cggacaacag gtgatggttt cctggtcgcg tgatgtgatg gtgccgctgg ttgaggagag
    13261 gtgaatggcg atgaatgtat tgcaatcacc ttcacgtcca ggtctgggta aggtgtccgg
    13321 tttcttctgg cataatccgg ggctggggct gtttttactg ctgcttggcc cgctaatgtg
    13381 gtttggcatt gtctatttcg gctcgctgct gacactgtta tggcagggat tttatacttt
    13441 tgacgatttc accatgtcgg taacgccgga actgacgctg gcgaatatcc gtgcgctgtt
    13501 taatccggcg aattacgaca tcattctccg cacgctgact atggctgtgg cagtcactat
    13561 cgccagcgcc attctggctt ttccaatggc gtggtatatg gcgcgctata ccagcgggaa
    13621 aatgaaagcg tttttttata ttgcggtaat gttgccgatg tgggcgagct acattgttaa
    13681 agcctatgcc tggacgttat tgctggcaaa agatggcgtg gctcagtggt ttttacaaca
    13741 tcttgggctg gaaccactgc tgactgcgtt ccttacatta cctgcggtgg gcggaaatac
    13801 gctgtcaact tccgggctgg ggcgctttct ggtgtttctc tatatctggt tgccgttcat
    13861 gatcctgccc gttcaggcgg cgcttgagcg tttgccgccg tcattgttgc aggcgtcggc
    13921 tgatctcggc gcacgtccac gacaaacctt tcgctatgtg gtgctgccgc tggcaatccc
    13981 gggtattgcc gctggctcta tctttacctt ctcactcaca ctgggcgatt ttatcgtccc
    14041 gcagctggtt ggtcctccag gatattttat cggcaatatg gtttattccc agcagggggc
    14101 gattggcaat atgccgatgg cggcggcatt caccctggtg ccgattattc tcatcgcact
    14161 gtacctggcg ttcgtgaaac gtctgggagc gttcgatgca ctctgaacgc gcaccgtttt
    14221 tcctcaaact ggcggcctgg ggcggcgttg ttttcctaca ttttcccatc ctgataatcg
    14281 ccgcctatgc gtttaacact gaagatgcgg cgtttagttt tccaccgcag ggcctgacgc
    14341 tgcgctggtt tagcgtggca gcacagcgta gtgatattct tgatgccgtg acactgtcac
    14401 ttaaagtggc ggcgctggcg acattaattg cgctggtgtt agggacgctg gcagctgccg
    14461 cgctgtggcg acgagacttt ttcggcaaaa acgccatttc gctgttactg ctgctgccca
    14521 ttgcgctgcc gggcattgtc actggtctgg cgttattaac cgcctttaaa accatcaatc
    14581 tggagccggg atttttcacc atcgtggtcg gtcatgcgac tttttgtgta gttgtggtgt
    14641 ttaacaatgt catcgcccgt tttcgccgca cctcctggag tctggttgag gcgtcaatgg
    14701 atcttggggc caatggctgg caaaccttcc gctacgtagt gttgccgaat ctcagttcgg
    14761 cgttactggc aggaggaatg ctggcgtttg ccttgtcgtt cgatgaaatc atcgttacga
    14821 cctttacggc aggtcatgaa cgaacgttac cgttgtggtt gctcaatcag cttgggcgac
    14881 cgcgtgatgt accggtaact aacgtggtgg cactgctggt tatgttggta acaaccttgc
    14941 cgatcctggg ggcctggtgg ctaacccgcg aaggcgacaa tggtcaataa ccactgatac
    15001 aggaatatgc tatgcaacat aagttactga ttaacggaga actggttagc ggcgaagggg
    15061 aaaaacagcc tgtctataat ccggcaacgg gggacgtttt actggaaatt gccgaggcat
    15121 ccgcagagca ggtcgatgct gctgtgcgcg cggcagatgc agcatttgcc gaatgggggc
    15181 aaaccacgcc gaaagtgcgt gcggaatgtc tgctgaaact ggctgatgtt atcgaagaaa
    15241 atggtcaggt ttttgccgaa ctggagtccc gtaattgtgg caaaccgctg catagtgcgt
    15301 tcaatgatga aatcccggcg attgtcgatg tttttcgctt tttcgcgggt gcggcgcgct
    15361 gtctgaatgg tctggcggca ggtgaatatc ttgaaggtca tacttcgatg atccgtcgcg
    15421 atccgttggg ggtcgtggct tctatcgcac cgtggaatta tccgctgatg atggccgcgt
    15481 ggaaacttgc tccggcgctg gcggcaggga actgcgtagt gcttaaacca tcagaaatta
    15541 ccccgctgac cgcgttgaag ttggcagagc tggcgaaaga tatcttcccg gcaggcgtga
    15601 ttaacatact gtttggcaga ggcaaaacgg tgggtgatcc gctgaccggt catcccaaag
    15661 tgcggatggt gtcgctgacg ggctctatcg ccaccggcga gcacatcatc agccataccg
    15721 cgtcgtccat taagcgtact catatggaac ttggtggcaa agcgccagtg attgtttttg
    15781 atgatgcgga tattgaagca gtggtcgaag gtgtacgtac atttggctat tacaatgctg
    15841 gacaggattg tactgcggct tgtcggatct acgcgcaaaa aggcatttac gatacgctgg
    15901 tggaaaaact gggtgctgcg gtggcaacgt taaaatctgg tgcgccagat gacgagtcta
    15961 cggagcttgg acctttaagc tcgctggcgc atctcgaacg cgtcagcaag gcagtagaag
    16021 aggcgaaagc gacagggcac atcaaagtga tcactggcgg tgaaaagcgc aagggtaatg
    16081 gctattacta tgcgccgacg ctgctggctg gcgcattaca ggacgatgcc atcgtgcaaa
    16141 aagaggtatt tggtccagta gtgagtgtta cgcccttcga caacgaagaa caggtggtga
    16201 actgggcgaa tgacagccag tacggacttg catcttcggt atggacgaaa gatgtgggca
    16261 gggcgcatcg cgtcagcgca cggctgcaat atggttgtac ctgggtcaat acccatttca
    16321 tgctggtaag tgaaatgccg cacggtgggc agaaactttc tggttacggc aaggatatgt
    16381 cactttatgg gctggaggat tacaccgtcg tccgccacgt catggttaaa cattaaggat
    16441 aatattgcag atcgtaagag tatgagatga tcttgcgtac tgtcagagca ctgatttctc
    16501 tgacagtacg tgctgcgtgc aaaatcacta catcaaataa accagccaaa tctcatagag
    16561 ataagagtaa acaaaccaac agcagcaaag aaatttatca gtactacagt tctactggaa
    16621 acattcattt ttgccacctt ttatcattgc ccctatgtgt atagtacggg ttaagaaaat
    16681 ccgcaataat actcattctg aagatggata agggcaagtt gctgtttgat gattttttct
    16741 caaactggtg aaaaaacttg atgcacgtca aaaaatgacg catatttgcg cgcgttttat
    16801 tcatctggct ggacgcccgt acatgtctct ctatcaacac atgcttgttt tttatgcggt
    16861 tatggcagca atcgcatttc ttatcacctg gtttctttct cacgataaga aacgcatccg
    16921 tttcttaagc gcctttctgg tgggggcaac atggccgatg agtttcccgg tggcgctgtt
    16981 gttttcactg ttttaaatct tactcactgg cttgacggca ccacgcagac ttatatcatt
    17041 tggatgaatc gataaatttc acaagtggct aaggagaaag tatgtcgcat ctggatgaag
    17101 tcatcgcgcg cgtggatgcc gcgattgaag agagcgtcat tgcccatatg aacgaattat
    17161 taatcgccct gagcgatgac gcggagttaa gtcgggaaga tcgctacacc cagcagcaac
    17221 gtctgcgcac agcgatcgcc catcacggtc gcaagcataa agaagatatg gaagcgcgcc
    17281 acgaacagtt aaccaaaggc ggcaccatcc tctgattaaa atgagcgtct ggctaccaac
    17341 caggcgccaa ccacaagtaa aattgcgcca caaattgggc cgaacaacgc ccgtagtggt
    17401 acgccatgac tgcggaagat atccagcatc agaccgccaa tcagctgact ggcgaccagt
    17461 acagcaatag ttgtcgccgc tcccacattc tgatatccgc tgatactggc gaagacaaaa
    17521 aacgatccca gcaagccagg tataagtgtc caccagcgca cgctggacac cagttcgcca
    17581 aaccccgcca taccttgttt aaaccataaa atagaaacaa agagcacaat ccccaccagt
    17641 gagttcagca acatggcgat gagaatggta gaggaggtct gggtgatgcg caccatcagc
    17701 gtgttctgga caaccagacc aattccggcg gcaatcaaaa aagcaagggt gagcgactga
    17761 ttcatccaat cgcgtccggt tcagtgcgct cgtcgagttg caactgcata aatgtcagat
    17821 ccagccaacg accaaattta gtgcctacct gcggcatttg cgcggtgacg acaaatccca
    17881 gcgactggtg gagatgcagc gaggcctgat tttgcgattc gatcccggcg accatgacat
    17941 gcttcccgca atcccgcgct tcatcaatca atcggcttaa caatttacgc cccagacctt
    18001 tgccctgatg atcgggatgg acataaaccg aatgttccac ggtatggcga aaaccatcga
    18061 aactacgcca gtcgccaaac gaggcatatc ccgtcactac gccgttttcc tcgctcacca
    18121 gcactggata acctgctaaa gtccgcgctt caaaccaggc aatgcggtta tcagcatcca
    18181 ccgtttggtc attccagata gccgccgtat acaacacggc gtggttataa atttccgcaa
    18241 tggcagcaca gtcggctttg cgggcaaaac ggatggacat gtctggcctc aataaaataa
    18301 tgatgatgat gttatcaata ctatcgaaaa cagcccgaag caacggattc ctcgatgaaa
    18361 ttattgcgtg ttgcagaggg gatgtgacgg ctgcaaacaa aaccaatccc gtgagcctgc
    18421 tactattgat ggattcatgc caaaagcaca ggagagcatt atggggcaac aaaagcagcg
    18481 taatcgacgt tgggttctgg cctcgcgtcc acatggcgca cctgttccgg agaatttccg
    18541 tcttgaagaa gatgatgtcg ccacaccggg tgaaggacag gtgttactgc gcacagttta
    18601 tttgtccctg gacccgtata tgcgtggacg tatgagcgat gagccatctt attcaccgcc
    18661 tgttgatatt ggcggcgtga tggtcggcgg tacggtgagc cgtgtcgtgg agtcgaatca
    18721 tcctgattat cagtctggcg actgggtgct gggctacagt ggatggcaag actatgacat
    18781 atccagtggt gatgatctgg tgaaacttgg cgatcatccg caaaatccat cgtggtcgct
    18841 gggtgtgcta gggatgccag gctttaccgc ttatatgggc ctactggata tcggtcagcc
    18901 taaagagggc gaaacgttgg tggtagctgc ggcgacagga ccagtggggg cgacggtggg
    18961 gcaaatcggc aaacttaaag gttgcagagt ggtgggggta gccggtggcg cggaaaaatg
    19021 ccgccatgct accgaggtgt taggcttcga tgtttgtctt gatcaccacg cggatgattt
    19081 tgccgaacaa ctggcgaaag cgtgcccaaa aggtattgat atctattatg aaaacgtggg
    19141 cggtaaggta ttcgatgcgg tgctaccgtt acttaataca tctgcgcgca ttcccgtctg
    19201 cggattagtg agcagctata acgctacaga gctaccaccc ggtccggatc gtttacctct
    19261 gttgatggct acagtgctga aaaaacgtat tcgcttgcaa ggttttatta tcgctcagga
    19321 ttatggtcac cgcatccatg agtttcagag ggagatgggg caatgggtga aagaggataa
    19381 aatccactac cgcgaagaaa ttactgacgg tttagagaat gcgccacaga cgtttatcgg
    19441 cctgctgaag ggtaaaaact tcggcaaagt ggtgatccgc gtggcgggtg atgattaaag
    19501 tttcaacggc ggcgtaagcc gccataaaaa tccaggcaaa aagcttattt tcagctttaa
    19561 ttaactaacc acatcattgt tctgctgcta ataacaacaa aggtgagtgg tttatgatta
    19621 ttcactttaa tacaccaggt gaattccttc tgccatgcag gcagggttgg acagaaaaca
    19681 cgcgaaggaa ttaaaatgcc tggaacggga aaaatgaaac atgtcagttt gactctgcag
    19741 gttgagaacg acctgaaaca tcagcttagt attggcgcat taaaacctgg cgcacgcctg
    19801 attactaaaa atctggcgga gcaattaggt atgagtatta cacctgtgcg tgaagcatta
    19861 ttacgtctgg tttcggtgaa tgcgctttct gtcgcacctg cacaagcatt tacagttccg
    19921 gaagtgggga aacgtcaatt agacgaaatc aatcggatcc gctacgaact ggaattaatg
    19981 gcagttgctc tggctgttga aaacctcacc ccgcaagacc ttgcggaact ccaggaattg
    20041 ctcgagaaat tacagcaggc gcaagaaaag ggcgacatgg aacaaatcat taatgtaaac
    20101 aggctatttc gcttagcgat ttatcatcgc tcaaatatgc ccatcctgtg tgagatgatt
    20161 gagcaactgt gggtcaggat ggggcctggt ttatattatc tctatgaagc gattaatcca
    20221 gcggaattac gggagcatat agaaaactat catctgttac tcgctgcgtt aaaagcaaaa
    20281 gacaaagagg gatgcagaca ttgtcttgct gaaattatgc aacaaaatat tgctatttta
    20341 taccagcaat actatcgtta aagtaaatgc ccggcaaata ccgggcatca aggtaattac
    20401 tcaaatctcc acgcaatatt catgccgaca ccataatttc gtccgggcga aggttcgtaa
    20461 tatcgcccgt ttgactcatt gacaatgaca gaaccaacgt attctttatc gaataaatta
    20521 tcgacacgac caaataaatc cacagttaaa ttgtggtaat tgtatttata cccggtgaat
    20581 aagccgacga gagtataaga cggcgctttt gccgtatttt catcatctgc cataatatcg
    20641 cccatataac gcgcttccgt gcctgcatac caaccatctt ccggtacata acctatcgac
    20701 gcaaagccca tattacgggc gatccctggc atccgattac cgttacaatc ctgttcattg
    20761 caaacattgc tgcgataggt cgcatcaagc caggtccagg acgcgtttac gcgaaaatct
    20821 cctgcgaaac gttgatccca tgccagttca gcgccttgac gacgggtctt tccggcattt
    20881 ttgtaagtcg tacgcccacc gctactgcta tcgacaacaa tttcatcatc agtgtcggtc
    20941 tgaaacaatg cgagactaag cagcccatca ccaatacgcg ttttactgcc gatctcaatt
    21001 gtatcgttgg tggatggttt taaacctaag ttcataccgc tttgcccatc agcacgataa
    21061 gacagctcat taatcgtcgg cgtttcaaaa cctcgcccgg ctgccagata gatattccag
    21121 gcatcggtca ttgcatattt taacgaaccg gcaggtagcc atttatgata actggcatca
    21181 ccgctgtcat cgccgttacc cggagtaacg taatggtcgt tggaatcaaa ccacacggag
    21241 ctgtagcgca cgccagcatc cagcgacagt ttttcgctca gctgccactg cgtctgtaaa
    21301 tagggatcga tgttccacat cagattgcgt tcgtcgcgac gcaactcacc tttttgcccg
    21361 tactccggca tgccgctatt caggcggaag ttattgtagc ccttgcggtt ttcactcatg
    21421 ttttcgtagt tcaggccggt agtgaacgtg accggaacgc ccagttcacc acggtgtgtc
    21481 cagcggctgt ctattccctg gtaatggcgt tgcagggtaa tcacgccgcc cgcatgtgac
    21541 gggttaagtt gtggtgccat gggtattgac tggtactggg tcgtttctcg ctctccggca
    21601 tacatcatca cactcatatc atcccgcgaa ctcaggctac gctcatagcg caacccagcc
    21661 tgagtttgct tgatggtttt tcgcgtgtcg tactgttctg cacgaggcgc ttgttgtgga
    21721 ttagccttcc attctgcttt ggttagccca cctgggtcat ctgctttgat atccacacta
    21781 ttgaaaatca gacttaattt gctggcttca tcaatgcgta cgcccagttt ggcattggct
    21841 aaatttttct gtgcgccact atggtcacga tagccgtggg tcgtaaaacg cgtggttgag
    21901 acggtgtaat cgacatcgcc aggctgtgtg ccgtctcccg ttgcgcccgt tgctttcagc
    21961 ccatagcgcc agctgccaaa actgccgtag taactactgg cttcaatggt tggtggctgt
    22021 tgtccggtct gggtggtgac attcattacc ccaccagacg cgttgccata cagggcagag
    22081 aaggggccac gcagcacttc cacattttgc acactgctta aatcgatgtt ggatgtttgc
    22141 ccttgcccgt cgggcatggt ggcgggaata ccgtccacat acaggcgaat accgcgaata
    22201 ccgtaagtgg agcgggagcc aaatccgcga atcgacagct gtaaatcttg cgcatagttc
    22261 tgccggtttt gtacctgcaa accaggcacg ccggtcagtg attcggacaa gttaatgcgc
    22321 ggtgttgcca ggcgcatctc ctcgccatcc accacgctta ctgctgctgg ggtatccagt
    22381 tctgaaacca cctgcggtgc ggcactgaca atcatagtct gttcatcagc ggcaaaaaca
    22441 acgggggaaa ggacaagcag tgcgggcaaa acggtctgtc ggacggaaaa aatcttcatg
    22501 aaaaaagcca ggttaagaat gggaaaacgc cgtcatggta atgaaattgt aaatttatgg
    22561 aaaatgaaac ggcacaatac gttaagtaat tgagaaaatt gtagtcgtaa cggcaagaaa
    22621 tgctccacat ttgagaaaat aatgattacc attcccattt ataacaagag cgtaacgatg
    22681 attacgctta gcgaagcatt gtgaagcagc aaaaatatcg gttcatcaaa gggagtcgtc
    22741 atgcatttac gtcatctgtt ttcatcgcgc ctgcgtggtt cattactgtt aggttcattg
    22801 cttgttgttt catcattcag tacgcaggcc gcagaagaaa tgctgcgtaa agcggtaggt
    22861 aaaggtgcct acgaaatggc ttatagccag caagaaaacg cgctgtggct cgccacttcg
    22921 caaagccgca aactggataa aggtggcgtg gtttatcgtc ttgatccggt cactctggaa
    22981 gtgacgcagg cgatccataa cgatctcaag ccgtttggtg ccaccatcaa taacacgact
    23041 cagacgttgt ggtttggtaa caccgtaaac agcgcggtca cggcgataga tgccaaaacg
    23101 ggcgaagtga aaggccgtct ggtgctggat gatcgtaagc gcacggaaga ggtgcgcccg
    23161 ctgcaaccgc gtgagctggt agctgacgat gccacgaaca ccgtttacat cagtggtatt
    23221 ggtaaagaga gcgtgatttg ggtcgttgat ggcgggaata tcaaactgaa aaccgccatc
    23281 cagaacaccg gtaaaatgag taccggtctg gcgctggata gcgaaggcaa acgtctttac
    23341 accactaacg ctgacggcga attgattacc atcgacaccg ccgacaataa aatcctcagc
    23401 cgtaaaaagc tgctggatga cggcaaagag cacttcttta tcaacattag ccttgatacc
    23461 gccaggcagc gtgcatttat caccgattct aaagccgcag aagtgttagt ggtcgatacc
    23521 cgtaatggca atattctggc gaaggttgcg gcaccggaat cactggctgt gctgtttaac
    23581 cccgcgcgta atgaagccta cgtaacgcat cgtcaggcag gtaaagtcag tgtgattgac
    23641 gcgaaaagct ataaagtggt gaaaacgttc gatacgccga ctcatccaaa cagcctggcg
    23701 ctgtctgccg atggcaaaac gctgtatgtc agtgtgaaac aaaaatccac taaacagcag
    23761 gaagctaccc agccagacga tgtgattcgt attgcgctgt aatagatatg gcgagggtga
    23821 aaacggtgag acttgcctgc cttttatcac ggcgtatccg gcactttcgt cagtaatctg
    23881 aatttgcccg gcacgtagcc gggcaatttt gcaattaact cgccgtttca ggcttaaaca
    23941 caatttcctg tttttcttca tcttcctcga cgactggcgc agtgctgtga atttcagcaa
    24001 cgcgtttgcg cacaccaaac cagcctataa ccagcaaaat accgataatc ggcagcgccg
    24061 cgatagtata agtcccgttc gggtaatcga acgccatcag cacaaggaca ctcagtaaaa
    24121 acagtaatgt cagccaggaa gtgaagggcg cgccaggcag tttaaaactg acatccgctg
    24181 ctttgccttc tttaatcgct ttacgcaggc gcatctggca cacgatgata aacgcccatg
    24241 aagcgatgat tcccagcgac gcgaagttca acacaatctc aaatacgcgc gacggcacca
    24301 gatagttgag gaatacgccg acgacataca caactagtgt cgccagaatc ccggcatacg
    24361 gcacatgctg acgactcatt ttcgccataa aactcggtgc ggaaccgccc atcgccattg
    24421 agcgcagaat acgtccggtg cagtacagac ctgaattcag gctggagagg gcagcggtca
    24481 gcaccacaat gttcataatg ctgccgatat atggcacacc cagtttagag aaaaacgtca
    24541 cgaacggact ttgccccgcc tgatacgcgc tccacggcaa taacataacc agcaacacca
    24601 cggagccgac gtaaaacagg ccaatacgcc aaatcacact gttaatggct ttaggcacca
    24661 tggtctgcgg atctttacat tctccggcag ctgtacccac catttcaatg gaggcaaaag
    24721 caaacactac gccctgaatc aacaccagcg caggcagcaa accgtggggg aagaagccgc
    24781 cattatcggt gattaaatga aagccagtgg tgttgccatc cagcggctga ccactaccga
    24841 ggaacactgt acccacgacc aaaaaggtca caatggcgag cactttaata agcgcaaacc
    24901 agaactccat ctccgcaaac catttcacac cgatcatatt catggtgcca acgatggtaa
    24961 gtgcagcgag cgcaaagacc cactgcggca cgccgccaaa cgcaccccag taatgcatat
    25021 acagagcgac ggcggtaata tcaacaatcc ccgtcatcgc ccagttgatg aagtacatcc
    25081 agccagcaac ataagcggct ttctcaccca aaaactcacg ggcataagaa acaaaactgc
    25141 cactggaagg gcggtgtagc accagctcac ccaatgcacg cagaataaaa aacgaaaaca
    25201 agccacaaat taaataaacc agtgccagtg cgggccccgc catttgcagt cgggctcctg
    25261 cacctaaaaa caagccggtg ccaatcgcgc cgccaatggc gatcatctgc acctggcgat
    25321 tgcccatcgc tttgtgatac ccctcttcgt gggcattaag ccagcggcgt ttcgcggcgt
    25381 gttgatctga agtgtcggtg tcgtgtttac tcattgctct ccctgattgc tttaatgaaa
    25441 aagtcatata agttgccatg aacaatgttt attcatcctg gcgatgatag ttatcaccat
    25501 tattctttat gggtataaaa ctatcggcgc agcatcctac ccgttatcga taaacgatgc
    25561 aaaacatccc cttacaatcc tgaaggggat taatacaact gacgaaaaaa tgacaaatcc
    25621 ttttgctggt taacctgtgt actgtcctac acttaatctt taaaagattg tgaggggcat
    25681 atgattaagg tgtatggcgt acccggatgg ggctctacaa tcagtgagct gatgctaaca
    25741 ctggctgata ttccttatca gttcgttgat gtcagtggtt ttgaccacga gggagcttca
    25801 cgcgagttat tgaaaaccct gaacccgttg tgtcaggttc cgacactggc attggaaaat
    25861 gacgagatta tgacggagac agcggcgatt gcattgatgg ttctcgatcg tcgcccggac
    25921 cttgcgccac cggttgggcg cgccgaacgt cagctgtttc aacggctatt ggtctggctg
    25981 gttgctaatg tctatccaac attcactttc gccgattacc ctgagcgttg ggctcctgac
    26041 gcacctgaac agttaaagaa gaatgttatt gaatatcgaa aatcgcttta tatctggttg
    26101 aattcgcagc tcactgctga accttatgcg tttggtgagc aactaacgct ggtggactgt
    26161 tatctttgca ctatgcgcac atgggggcct gggcatgaat ggtttcagga taatgccacg
    26221 aatatcagtg cgattgctga tgctgtatgt cagttaccga aattacaaga agtattaaaa
    26281 aggaatgaaa ttatttgagt gggataccag aagattatgt tatttattat tcagtaactt
    26341 tatccacaat gatgggcgta attaattaaa ttcatggtat gttttttaat ttatatcact
    26401 ctccttttca ttcagcgtgt ctatttcatt tcctctgaaa agaaactaac tattcacatt
    26461 gtgcagatgt ttcagttgtt atcacaggca ttctataatc tcaaaatgtt tttaatgatg
    26521 gatatgctcg gagttggaga tgcaattaat attaatacaa ataaaaatat ccggcag
//
LOCUS       DAPOAV010000060        26503 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.060, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000060 DAPOAV010000000
VERSION     DAPOAV010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26503
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.060"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            16..1485
                     /gene="gspA"
                     /locus_tag="RN951_002865"
     CDS             16..1485
                     /gene="gspA"
                     /locus_tag="RN951_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspA"
                     /protein_id="HDX2527838.1"
                     /translation="MSTRREVILSWLCEKRQTWRLCYLLGEAGSGKTWLAQQLQKDKH
                     RRVITLSLVVSWQGKAAWIVTDDNAAEQGCRDSAWTRDEMAGQLLHALHRTDSRCPLI
                     IIENAHLNHRRILDDLQRAISLIPDGQFLLIGRPDRKVERDFKKQGIELVSIGRLTEH
                     ELKASILEGQNIDQPDLLLTARVLKRIALLCRGDRRKLALAGETIRLLQQAEQTSVFT
                     AKQWRMIYRILGDNRPRKMQLAVVMSGTIIALTCGWLLLSSFTATLPVPAWLIPVTPV
                     VKQDMTKDIAHVVMRDSEALSVLYGVWGYEVPADSAWCDQAVRAGLACKSGNASLQTL
                     VDQNLPWIASLKVGDKKLPVVVVRVGEASVDVLVGQQTWTLTHKWFESVWTGDYLLLW
                     KMSPEGESTITRDSSEEEILWLETMLNRALHISTEPSAEWRPLLVEKIKQFQKSHHLK
                     TDGVVGFSTLVHLWQVAGESAYLYRDEANISPETTVKGK"
     gene            1487..1906
                     /gene="gspB"
                     /locus_tag="RN951_002866"
     CDS             1487..1906
                     /gene="gspB"
                     /locus_tag="RN951_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative general secretion pathway protein GspB"
                     /protein_id="HDX2527839.1"
                     /translation="MFEFYIAAREQKETGHPGIFSRQKHSTIIYVICLLLICLWFAGM
                     VLVGGYARQLWVLWIVKAEVTVEAETPAFKQSTQHYFFKKQPLPVVESVEEEDDPGVA
                     VENAPSSSEDEENTVEESEEKAGLRERVKNALNELER"
     gene            2144..2455
                     /gene="rpsJ"
                     /locus_tag="RN951_002867"
     CDS             2144..2455
                     /gene="rpsJ"
                     /locus_tag="RN951_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014268624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HDX2527840.1"
                     /translation="MQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPT
                     RKERFTVLISPHVNKDARDQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISL
                     G"
     gene            2488..3117
                     /gene="rplC"
                     /locus_tag="RN951_002868"
     CDS             2488..3117
                     /gene="rplC"
                     /locus_tag="RN951_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000579825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HDX2527841.1"
                     /translation="MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDG
                     YRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFA
                     DVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKK
                     MAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA"
     gene            3128..3733
                     /gene="rplD"
                     /locus_tag="RN951_002869"
     CDS             3128..3733
                     /gene="rplD"
                     /locus_tag="RN951_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010304939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HDX2527842.1"
                     /translation="MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTR
                     AQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYR
                     GALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLA
                     ARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA"
     gene            3730..4032
                     /gene="rplW"
                     /locus_tag="RN951_002870"
     CDS             3730..4032
                     /gene="rplW"
                     /locus_tag="RN951_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HDX2527843.1"
                     /translation="MIREERLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIK
                     AAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE"
     gene            4050..4871
                     /gene="rplB"
                     /locus_tag="RN951_002871"
     CDS             4050..4871
                     /gene="rplB"
                     /locus_tag="RN951_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HDX2527844.1"
                     /translation="MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRN
                     NNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERR
                     YILAPKGLKAGDQIQSGVDAAIKPGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGT
                     YVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRP
                     TVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK"
     gene            4888..5166
                     /gene="rpsS"
                     /locus_tag="RN951_002872"
     CDS             4888..5166
                     /gene="rpsS"
                     /locus_tag="RN951_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HDX2527845.1"
                     /translation="MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNM
                     IGLTIAVHNGRQHVPVFVTDEMVGHKLGEFAPTRTYRGHAADKKAKKK"
     gene            5181..5513
                     /gene="rplV"
                     /locus_tag="RN951_002873"
     CDS             5181..5513
                     /gene="rplV"
                     /locus_tag="RN951_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HDX2527846.1"
                     /translation="METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAA
                     VLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSH
                     ITVVVSDR"
     gene            5531..6232
                     /gene="rpsC"
                     /locus_tag="RN951_002874"
     CDS             5531..6232
                     /gene="rpsC"
                     /locus_tag="RN951_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HDX2527847.1"
                     /translation="MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLT
                     KELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQIN
                     IAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGA
                     EIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPE
                     KPAAQPKKQQRKGRK"
     gene            6245..6655
                     /gene="rplP"
                     /locus_tag="RN951_002875"
     CDS             6245..6655
                     /gene="rplP"
                     /locus_tag="RN951_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017805229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HDX2527848.1"
                     /translation="MLQPKRTKFRKMHKGRNRGLAQGTDVSFGSFGLKAVGRGRLTAR
                     QIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVL
                     YEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM"
     gene            6655..6846
                     /gene="rpmC"
                     /locus_tag="RN951_002876"
     CDS             6655..6846
                     /gene="rpmC"
                     /locus_tag="RN951_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HDX2527849.1"
                     /translation="MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLK
                     QVRRDVARVKTLLNEKAGA"
     gene            6846..7100
                     /gene="rpsQ"
                     /locus_tag="RN951_002877"
     CDS             6846..7100
                     /gene="rpsQ"
                     /locus_tag="RN951_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006817275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HDX2527850.1"
                     /translation="MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKL
                     HVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL"
     gene            7265..7636
                     /gene="rplN"
                     /locus_tag="RN951_002878"
     CDS             7265..7636
                     /gene="rplN"
                     /locus_tag="RN951_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015817037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HDX2527851.1"
                     /translation="MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIK
                     EAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIFGP
                     VTRELRSEKFMKIISLAPEVL"
     gene            7647..7961
                     /gene="rplX"
                     /locus_tag="RN951_002879"
     CDS             7647..7961
                     /gene="rplX"
                     /locus_tag="RN951_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HDX2527852.1"
                     /translation="MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKK
                     HQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSET
                     IK"
     gene            7976..8515
                     /gene="rplE"
                     /locus_tag="RN951_002880"
     CDS             7976..8515
                     /gene="rplE"
                     /locus_tag="RN951_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HDX2527853.1"
                     /translation="MAKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAI
                     ADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFER
                     LITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTA
                     KSDEEGRALLAAFDFPFRK"
     gene            8530..8835
                     /gene="rpsN"
                     /locus_tag="RN951_002881"
     CDS             8530..8835
                     /gene="rpsN"
                     /locus_tag="RN951_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005599304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HDX2527854.1"
                     /translation="MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNASDEDRWNA
                     VLKLQTLPRDSSPSRQRNRCRQTGRPHGFLRKFGLSRIKVREAAMRGEIPGLKKASW"
     gene            8869..9261
                     /gene="rpsH"
                     /locus_tag="RN951_002882"
     CDS             8869..9261
                     /gene="rpsH"
                     /locus_tag="RN951_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HDX2527855.1"
                     /translation="MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEG
                     FIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIA
                     VVSTSKGVMTDRAARQAGLGGEIICYVA"
     gene            9274..9807
                     /gene="rplF"
                     /locus_tag="RN951_002883"
     CDS             9274..9807
                     /gene="rplF"
                     /locus_tag="RN951_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003031129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HDX2527856.1"
                     /translation="MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVK
                     HADNTLTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNV
                     INLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGK
                     GVRYADEVVRTKEAKKK"
     gene            9817..10170
                     /gene="rplR"
                     /locus_tag="RN951_002884"
     CDS             9817..10170
                     /gene="rplR"
                     /locus_tag="RN951_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HDX2527857.1"
                     /translation="MDKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNG
                     SEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGR
                     VQALADAAREAGLQF"
     gene            10185..10688
                     /gene="rpsE"
                     /locus_tag="RN951_002885"
     CDS             10185..10688
                     /gene="rpsE"
                     /locus_tag="RN951_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004106339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HDX2527858.1"
                     /translation="MAHIEKQAGELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNG
                     RVGFGYGKAREVPAAIQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEG
                     TGIIAGGAMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGKS
                     VEEILGK"
     gene            10692..10871
                     /gene="rpmD"
                     /locus_tag="RN951_002886"
     CDS             10692..10871
                     /gene="rpmD"
                     /locus_tag="RN951_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012147215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HDX2527859.1"
                     /translation="MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAI
                     RGMINAVSFMVKVEE"
     gene            10875..11309
                     /gene="rplO"
                     /locus_tag="RN951_002887"
     CDS             10875..11309
                     /gene="rplO"
                     /locus_tag="RN951_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011095501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HDX2527860.1"
                     /translation="MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGG
                     GVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEVRLSDLAKVEGGVVDLNTLKAANIIG
                     IQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE"
     gene            11317..12648
                     /gene="secY"
                     /locus_tag="RN951_002888"
     CDS             11317..12648
                     /gene="secY"
                     /locus_tag="RN951_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004868351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HDX2527861.1"
                     /translation="MAKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGI
                     DAAVLAKLLEQQRGTIIEMFNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPTL
                     AEIKKEGESGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTA
                     VVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFL
                     VLLLVAVLVFAVTFFVVFVERGQRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIP
                     AIFASSIILFPATIASWFGGGTGWNWLTTISLYLQPGQPLYVLLYASAIIFFCFFYTA
                     LVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLVGALYITFICLIPEFMR
                     DAMKVPFYFGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYGR"
     gene            12680..12796
                     /gene="rpmJ"
                     /locus_tag="RN951_002889"
     CDS             12680..12796
                     /gene="rpmJ"
                     /locus_tag="RN951_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020322760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HDX2527862.1"
                     /translation="MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG"
     gene            12943..13299
                     /gene="rpsM"
                     /locus_tag="RN951_002890"
     CDS             12943..13299
                     /gene="rpsM"
                     /locus_tag="RN951_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019935869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HDX2527863.1"
                     /translation="MARIAGINIPDHKHAVIALTSIYGVGKTRSKAILAAAGIAEDVK
                     ISELSEGQIDTLRDEVAKFVVEGDLRREISMSIKRLMDLGCYRGLRHRRGLPVRGQRT
                     KTNARTRKGPRKPIKK"
     gene            13316..13705
                     /gene="rpsK"
                     /locus_tag="RN951_002891"
     CDS             13316..13705
                     /gene="rpsK"
                     /locus_tag="RN951_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HDX2527864.1"
                     /translation="MAKAPIRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGW
                     ATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNA
                     AGFRITNITDVTPIPHNGCRPPKKRRV"
     gene            13739..14359
                     /gene="rpsD"
                     /locus_tag="RN951_002892"
     CDS             13739..14359
                     /gene="rpsD"
                     /locus_tag="RN951_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004410410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HDX2527865.1"
                     /translation="MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGAR
                     KPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVV
                     YRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALE
                     LAEQREKPTWLEVDAGKMEGTFKRKPERSDLSADINEHLIVELYSK"
     gene            14385..15374
                     /gene="rpoA"
                     /locus_tag="RN951_002893"
     CDS             14385..15374
                     /gene="rpoA"
                     /locus_tag="RN951_002893"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HDX2527866.1"
                     /translation="MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALR
                     RILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTL
                     NKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIH
                     SEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIR
                     RAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIH
                     YIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIADE"
     gene            15415..15798
                     /gene="rplQ"
                     /locus_tag="RN951_002894"
     CDS             15415..15798
                     /gene="rplQ"
                     /locus_tag="RN951_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HDX2527867.1"
                     /translation="MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKEL
                     RRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGF
                     RAGDNAPMAYIELVDRSEKAEAAAE"
     gene            15905..16273
                     /locus_tag="RN951_002895"
     CDS             15905..16273
                     /locus_tag="RN951_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1992 domain-containing protein"
                     /protein_id="HDX2527868.1"
                     /translation="MWLLDQWAERHIAEAQAKGEFDNLAGSGEPLILDDDSHVPPELR
                     AGYRLLKNAGCLPPELEQRREAIQLLDILRGIRHDDPQYQEVSRRLSLLELKLRQAGL
                     STDFLRGDYADKLLDKINDN"
     gene            16284..16709
                     /gene="zntR"
                     /locus_tag="RN951_002896"
     CDS             16284..16709
                     /gene="zntR"
                     /locus_tag="RN951_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(2+)-responsive transcriptional regulator"
                     /protein_id="HDX2527869.1"
                     /translation="MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTESD
                     LQRLKFIRHARQLGFSLESIRELLSIRIDPEHHTCQESKGIVQERLQEVEARIAELQS
                     MQRSLQRLNDACCGTAHSSVYCSILEALEQGASGVKSGC"
     gene            16765..16983
                     /gene="arfA"
                     /locus_tag="RN951_002897"
     CDS             16765..16983
                     /gene="arfA"
                     /locus_tag="RN951_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alternative ribosome-rescue factor ArfA"
                     /protein_id="HDX2527870.1"
                     /translation="MSRYQHTKGQIKDNAIEALLHDPLFRQRVEKNKKGKGSYMRKGK
                     HGNRGNWEASGKKVNHFFTTGLLLSGVC"
     gene            complement(16980..17390)
                     /gene="mscL"
                     /locus_tag="RN951_002898"
     CDS             complement(16980..17390)
                     /gene="mscL"
                     /locus_tag="RN951_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large-conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HDX2527871.1"
                     /translation="MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPP
                     LGLLIGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL
                     NRKKEEPAAAPAPTKEEVLLTEIRDLLKEQNNRS"
     gene            complement(17520..18896)
                     /gene="trkA"
                     /locus_tag="RN951_002899"
     CDS             complement(17520..18896)
                     /gene="trkA"
                     /locus_tag="RN951_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HDX2527872.1"
                     /translation="MKIIILGAGQVGGTLAENLVGENNDITVVDTNGERLRTLQDKFD
                     LRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNMVACQVAYSLFNTPNRIARIRSP
                     DYVRDADKLFHSDAVPIDHLIAPEQLVIDNIYRLIEYPGALQVVNFAEGKVSLAVVKA
                     YYGGPLIGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHI
                     RAVMSELQRLEKPYKRIMLVGGGNIGAGLARRLEKDYSVKLIERNQQRAAELAEKLQN
                     TIVFFGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAKRMGAKKVMVLIQRRA
                     YVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHGDESTS
                     RVVGRVIDEIKLPPGTIIGAVVRGNDVMIANDNLRIEQGDHVIMFLTDKKFITDVERL
                     FQPSPFFL"
     gene            complement(18918..20207)
                     /gene="rsmB"
                     /locus_tag="RN951_002900"
     CDS             complement(18918..20207)
                     /gene="rsmB"
                     /locus_tag="RN951_002900"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HDX2527873.1"
                     /translation="MKKQRNLRSMAAQAVEQVVEQGQSLSNILPPLQQKVSDKDKALL
                     QELCFGVLRTLSQLDWLINKLMARPMTGKQRTVHYLIMVGLYQLLYTRIPPHAALAET
                     VEGAIAIKRPQLKGLINGVLRQFQRQQEELLAEFNASDARYLHPSWLLKRLQKAYPEQ
                     WQSIVEANNQRPPMWLRVNRTHHSRDSWLALLDEAGMKGFPHADYPDAVRLETPAPVH
                     ALPGFEDGWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEVAPEAQVVAV
                     DIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRILLDAPCSATGVIRRH
                     PDIKWLRRDRDIPELAQLQSEILDAIWPHLKSGGTLVYATCSVLPEENSLQIKAFLQR
                     TADAELCETGTPEQPGKQNLPGAEEGDGFFYAKLIKK"
     gene            complement(20253..21200)
                     /gene="fmt"
                     /locus_tag="RN951_002901"
     CDS             complement(20253..21200)
                     /gene="fmt"
                     /locus_tag="RN951_002901"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HDX2527874.1"
                     /translation="MSESLRIIFAGTPDFAARHLDALLSSGHNVVGVFTQPDRPAGRG
                     KKLMPSPIKVLAEEKGLPVFQPVSLRPQENQQLVADLQADVMVVVAYGLILPKAVLEM
                     PRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLSCPIT
                     AEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETLVTYAEKLSKEEARIDWS
                     LSAAQLERCIRAFNPWPMSWLEIEGQPVKVWKASVIDTATNAAPGTILEANKQGIQVA
                     TGDGILNLLSLQPAGKKAMSAQDLLNSRREWFVPGNRLV"
     gene            complement(21215..21724)
                     /gene="def"
                     /locus_tag="RN951_002902"
     CDS             complement(21215..21724)
                     /gene="def"
                     /locus_tag="RN951_002902"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDX2527875.1"
                     /translation="MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEG
                     IGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVP
                     RAEKVKICALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVE
                     KLDRLKARA"
     gene            21854..22978
                     /gene="dprA"
                     /locus_tag="RN951_002903"
     CDS             21854..22978
                     /gene="dprA"
                     /locus_tag="RN951_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HDX2527876.1"
                     /translation="MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSQIDAVGLQQTGL
                     TLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSEFYPPQLLVTTDYPGALFVEGEL
                     HALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
                     GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGL
                     SKGVLVVEAALRSGSLVTARCALEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEP
                     EEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDEVTPVDVVAERAGQP
                     VPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV"
     gene            22950..23423
                     /locus_tag="RN951_002904"
     CDS             22950..23423
                     /locus_tag="RN951_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF494 domain-containing protein"
                     /protein_id="HDX2527877.1"
                     /translation="MFDVLMYLFETYIHTEAELRVDQDKLEQDLTDAGFEREDIYNAL
                     LWLEKLADYQEGLAEPMQLASDPLSMRIYTPEECERLDASCRGFLLFLEQIQVLNLET
                     REMVIERVLALDNAEFELDDLKWVILMVLFNIPGCENAYQQMEELLFEVNEGMLH"
     gene            23452..23994
                     /locus_tag="RN951_002905"
     CDS             23452..23994
                     /locus_tag="RN951_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /protein_id="HDX2527878.1"
                     /translation="MAKSALFTVRNNESCPKCGAELVIRSGKHGPFLGCSQYPACDYV
                     RPLKSSADGHIVKVLEGQVCPACGANLVLRQGRFGMFIGCINYPECEHTELIDKPDET
                     AITCPQCRTGHLVQRRSRYGKTFHSCDRYPECQFAINFKPIAGECPECHYPLLIEKKT
                     AQGVKHFCASKQCGKPVSAE"
     gene            23999..24571
                     /gene="tsaC"
                     /locus_tag="RN951_002906"
     CDS             23999..24571
                     /gene="tsaC"
                     /locus_tag="RN951_002906"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase type 1
                     TsaC"
                     /protein_id="HDX2527879.1"
                     /translation="MNNNLQGDAIAAAIDVLNEERVIAYPTEAVFGVGCDPDSETAVM
                     RLLELKQRPVDKGLILIAANYEQLKPYIDDTMLTDAQRETIFSRWPGPVTFVFPAPAT
                     TPRWLTGRFDSLAVRVTDHPLVVALCQAYGKPLVSTSANLSGLPPCRTVDEVRAQFGA
                     AFPVVPGETGGRLNPSEIRDALTGELFRQG"
     gene            24576..25394
                     /gene="aroE"
                     /locus_tag="RN951_002907"
     CDS             24576..25394
                     /gene="aroE"
                     /locus_tag="RN951_002907"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDX2527880.1"
                     /translation="METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFI
                     NTLNAFFRAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLKRLEDGRLLGDNTD
                     GIGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAK
                     LFAHTGSIQALGMDELEGHEFDLIINATSSGISGDIPAIPSSLIHPGIYCYDMFYQKG
                     KTPFLAWCEQRGSKRNADGLGMLVAQAAHAFLLWHGVLPDVEPVIKQLQEELSA"
     gene            25391..25648
                     /locus_tag="RN951_002908"
     CDS             25391..25648
                     /locus_tag="RN951_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1488 domain-containing protein"
                     /protein_id="HDX2527881.1"
                     /translation="MNQAIQFPDREEWDENKKCVCFPALVNGMQLTCAISGESLAYRF
                     TGDTPEQWLASFRQHRWDLEEEAENLIQEQSEDDQGWVWLP"
     gene            complement(25624..26178)
                     /locus_tag="RN951_002909"
     CDS             complement(25624..26178)
                     /locus_tag="RN951_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417738.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HDX2527882.1"
                     /translation="MSDVLRPYRDLFPQIGQRVMIDDSSVVIGDVRLADDVGIWPLVV
                     IRGDVHYVQIGARTNIQDGSMLHVTHKSSYNPDGNPLTIGEDVTVGHKVMLHGCTIGN
                     RVLVGMGSILLDGAIVEDDVMIGAGSLVPQNKRLESGYLYLGSPVKQIRPLSDEEKAG
                     LRYSANNYVKWKDEYLDQGNQTQP"
BASE COUNT         6758 a         6258 c         6948 g         6539 t
ORIGIN      
        1 aaaacaggaa gttctatgtc tacgagaaga gaagttattc tttcctggtt gtgtgagaaa
       61 cgtcaaacct ggcgtctatg ctatttgttg ggtgaggctg gaagtggaaa aacctggctg
      121 gcgcagcaac tgcaaaaaga taaacatcgc cgtgtgatta ctttaagcct cgttgtttcc
      181 tggcaaggta aggccgcatg gatcgttacc gacgataacg cggctgaaca gggctgccgt
      241 gacagcgcct ggacgcgaga tgagatggcg gggcaattac tgcatgcgct tcatcgaact
      301 gatagtcgct gccctcttat tattattgaa aatgctcacc tgaatcaccg ccgcatactt
      361 gatgatctcc aacgcgcaat atctcttatt cctgacggtc aatttttgct gatcggcaga
      421 cccgatcgaa aagtcgaacg tgattttaaa aaacagggca ttgaacttgt ctcgatagga
      481 cgtctgacgg agcacgaact taaggcaagc atccttgaag gtcagaatat tgaccaaccc
      541 gatctccttt taaccgccag agttctgaaa cggatagctt tattatgtcg gggcgatcgc
      601 agaaagctgg cgcttgccgg cgaaacaatt cgcttattac agcaagccga gcagaccagc
      661 gttttcacag caaaacaatg gcgaatgatt taccgcatat tgggtgataa ccgcccccgg
      721 aaaatgcagc ttgccgtggt gatgagtgga accattatcg ctcttacctg tggttggcta
      781 ctgctgtcct cttttacagc tacgttaccc gttcctgcgt ggctgatacc cgtaacgcca
      841 gtagttaaac aagatatgac taaggatatt gctcatgtgg tgatgcgcga tagtgaggcg
      901 ctaagcgtgt tatacggcgt atgggggtac gaggtcccag ctgattcggc ctggtgcgat
      961 caggcagtaa gagcggggct ggcatgtaaa agtgggaatg cttctttaca aacattggta
     1021 gatcagaatt tgccctggat cgcatcgctt aaagtcgggg acaaaaaatt gcctgttgtg
     1081 gtcgttcgcg tcggtgaggc tagcgttgat gtcctcgtag gtcagcaaac gtggacgctg
     1141 acacataaat ggtttgagtc ggtatggacg ggtgattatc ttctgttgtg gaaaatgtcg
     1201 ccggaagggg agagtaccat tacgcgtgat agcagcgagg aagagattct ctggctggaa
     1261 acgatgttaa accgcgcatt gcatatttcg acagaacctt cggcggagtg gcgtcccttg
     1321 ttggtagaaa aaataaagca atttcaaaaa agccaccact tgaaaactga cggtgttgtt
     1381 ggcttttcaa cgttagtaca tctctggcag gtggcagggg agagtgccta cttatatcgg
     1441 gatgaagcaa atatttcccc ggaaacaaca gtgaagggga aatgacatgt ttgaattcta
     1501 tatcgccgcg cgtgagcaga aagaaacagg tcaccctggt atcttctccc gacaaaaaca
     1561 cagcaccata atatatgtaa tttgtttatt actgatttgc ctgtggtttg caggaatggt
     1621 gctggttggt gggtatgcca ggcagctatg ggtgctttgg atagtaaaag ccgaagtcac
     1681 tgtagaggct gaaacgcccg cttttaaaca atcaacacaa cactatttct tcaaaaaaca
     1741 gccactcccc gtcgtcgaat ccgtcgagga ggaagatgac ccaggcgtcg cggttgagaa
     1801 tgccccctct tcttctgaag acgaagaaaa tactgtggaa gaaagcgaag agaaagccgg
     1861 tttaagagag cgtgtcaaaa atgcactgaa cgaacttgag agataacccg aaggctgttt
     1921 actttactag caatacgctt gcgttcggtg gttaagtatg tataatgcgc gggcttgtcg
     1981 tagttgacag caggttcaat ctgaacctca gttagccgaa tttggctacc taacaatgct
     2041 cccaatcggg gagctacgta agaacggtta cactctccca tcaatcgtaa tgggtctgag
     2101 gagtaatcat tttcgtttat aaaataattg gagctctggt ctcatgcaga accaaagaat
     2161 ccgtatccgc ctgaaagcgt ttgatcatcg tctgatcgat caagcaaccg cggaaatcgt
     2221 cgagactgcc aagcgcactg gtgcgcaggt ccgtggtccg atcccgctgc cgacacgcaa
     2281 agagcgcttc actgttctga tctccccgca cgtcaacaaa gacgcgcgcg atcagtacga
     2341 aatccgtact cacttgcgtc tggttgacat cgttgagcca accgagaaaa ccgttgatgc
     2401 tctgatgcgt ctggatctgg ctgccggtgt agacgtgcag atcagcctgg gttaatcagg
     2461 tcattgagcg attgagaggt tgaaacaatg attggtttag tcggtaaaaa agtgggtatg
     2521 acccgtatct tcacagaaga cggcgtttct atcccagtaa ccgtaatcga agttgaagca
     2581 aaccgcgtta ctcaggttaa agacctggct aacgatggct accgtgctat tcaggtgacc
     2641 accggtgcta aaaaagctaa ccgtgtgacc aagcctgaag ctggccactt cgctaaagct
     2701 ggcgtagaag ctggccgtgg tctgtgggaa ttccgcctgg ctgaaggcga agagttcact
     2761 gtaggtcaga gcattagcgt tgaactgttt gctgacgtta aaaaagttga cgtaactggc
     2821 acctctaaag gtaaaggttt cgcaggtacc gttaagcgct ggaacttccg tacccaggac
     2881 gctactcacg gtaactcctt gtctcaccgc gttccgggtt ctatcggtca gaaccagact
     2941 ccgggcaaag tgttcaaagg caagaaaatg gcaggtcaga tgggtaacga acgtgtaacc
     3001 gttcagagcc ttgacgtagt acgcgttgac gctgagcgca acctgctgct ggttaaaggt
     3061 gctgtcccgg gtgcaaccgg tagcgacctg atcgttaaac cagctgtgaa ggcgtaagga
     3121 gatagcaatg gaattagtat tgaaagacgc gcagagcgcg ctgactgttt ccgaaactac
     3181 cttcggtcgt gatttcaacg aagcgctggt tcaccaggtt gttgttgctt atgcagctgg
     3241 tgctcgtcag ggtactcgtg ctcagaagac tcgtgctgaa gtaactggtt ccggtaaaaa
     3301 accgtggcgc cagaaaggca ccggccgtgc gcgttctggt tctatcaaga gcccgatctg
     3361 gcgttctggt ggcgtgacct ttgctgctcg tccgcaggac cacagtcaaa aagttaacaa
     3421 gaagatgtac cgcggcgcgc tgaaaagcat cctgtccgaa ctggtacgtc aggatcgtct
     3481 gatcgttgtc gagaagttct ctgtagaagc gccgaaaact aagctgctgg cacagaaact
     3541 gaaagacatg gctctggaag atgtgctgat catcaccggt gagctggacg aaaacctgtt
     3601 cctggctgcg cgcaacctgc acaaggttga cgtacgcgat gcaactggta tcgacccggt
     3661 tagcctgatc gccttcgaca aagtcgtaat gactgctgat gctgttaagc aagttgagga
     3721 gatgctggca tgattcgtga agaacgtctg ctgaaggtgc tgcgtgcacc gcacgtttct
     3781 gaaaaagcgt ctactgcgat ggaaaaatcc aacaccatcg tactcaaagt tgctaaagac
     3841 gcgaccaaag cagaaatcaa agctgctgtg cagaaactgt ttgaagtcga agtcgaagtc
     3901 gttaacaccc tggtagttaa agggaaagtt aaacgtcacg gacagcgtat cggtcgtcgt
     3961 agcgactgga aaaaagctta cgtcaccctg aaagaaggcc agaatctgga cttcgttggc
     4021 ggcgctgagt aagtcggagg agtaatacaa tggcagttgt taaatgtaaa ccgacatctc
     4081 cgggtcgtcg ccacgtagtt aaagtggtta accctgagct gcacaagggc aaaccttttg
     4141 ctccgttgct ggaaaaaaac agcaaatccg gtggtcgtaa caacaatggc cgtatcacca
     4201 ctcgtcatat cggtggtggc cacaagcagg cttaccgtat tgttgacttc aaacgcaaca
     4261 aagacggtat cccggcagtt gttgaacgtc ttgagtacga tccgaaccgt tccgcgaaca
     4321 tcgcgctggt tctgtacaaa gacggtgaac gccgttacat cctggcccct aaaggcctga
     4381 aagctggcga ccagattcag tctggcgttg atgctgcaat caaaccaggt aacaccctgc
     4441 cgatgcgcaa catcccggtt ggttctactg ttcataacgt agaaatgaaa ccaggtaaag
     4501 gcggtcagct ggcacgttcc gctggtactt acgttcagat cgttgctcgt gatggtgctt
     4561 atgtcaccct gcgtctgcgt tctggtgaaa tgcgtaaagt agaagcagac tgccgtgcaa
     4621 ctctgggcga agttggcaat gctgagcata tgctgcgcgt tctgggtaaa gcaggtgctg
     4681 cacgctggcg tggtgttcgt ccgaccgttc gcggtaccgc gatgaacccg gtagaccacc
     4741 cacatggtgg tggtgaaggt cgtaactttg gtaagcaccc ggtaactccg tggggcgttc
     4801 agaccaaagg taagaagacc cgcagcaaca agcgtactga taaattcatc gtacgtcgcc
     4861 gtagcaaata attttagagg ataagccatg ccacgttctc tcaagaaagg tccttttatt
     4921 gacctgcact tgctgaagaa ggtagagaaa gcggtggaaa gcggagacaa gaagcccctg
     4981 cgcacttggt cccgtcgttc aacgatcttt cctaacatga tcggtttgac catcgctgtc
     5041 cataatggtc gtcagcacgt tccggtattt gtaaccgacg aaatggttgg tcacaaactg
     5101 ggtgaattcg caccgactcg tacttatcgc ggccacgctg ctgataaaaa agcgaagaag
     5161 aaataaggta ggaggaagag atggaaacta tcgctaaaca tcgccatgct cgttcttctg
     5221 ctcagaaggt tcgccttgtt gctgacctga ttcgcggtaa gaaagtgtcg caggctctgg
     5281 atattttgac ctacaccaac aagaaagcgg ctgtactggt caagaaagtt ctggaatctg
     5341 ccattgctaa cgctgaacac aacgatggcg ctgacattga cgatctgaaa gttacgaaaa
     5401 ttttcgtaga cgaaggcccg agcatgaagc gcattatgcc gcgtgcaaaa ggtcgtgcag
     5461 atcgcatcct gaagcgcacc agccacatca ctgtggttgt gtccgatcgc tgagactctg
     5521 gagactagca atgggtcaga aagtacatcc taatggtatt cgcctgggta ttgtaaaacc
     5581 atggaactct acctggtttg cgaacaccaa agaattcgct gacaacctgg acagcgattt
     5641 taaagtacgt cagtacctga ctaaggaact ggctaaagcg tccgtatctc gtatcgttat
     5701 cgagcgtccg gctaagagca tccgtgtaac cattcacact gctcgcccgg gtatcgttat
     5761 cggtaaaaaa ggtgaagacg tagaaaaact gcgtaaggtc gtagcggaca tcgctggcgt
     5821 tcctgcacag atcaacatcg ccgaagttcg taagcctgaa ctggacgcaa aactggttgc
     5881 tgacagcatc acttctcagc tggaacgtcg cgttatgttc cgtcgtgcta tgaagcgtgc
     5941 tgtacagaac gcaatgcgtc tgggcgctaa aggtattaaa gttgaagtta gcggccgtct
     6001 gggcggcgcg gaaatcgcac gtaccgaatg gtaccgcgaa ggtcgcgtac cgctgcacac
     6061 tctgcgtgct gacatcgact acaacacctc tgaagcgcac accacttacg gtgtaatcgg
     6121 cgttaaagtg tggatcttca aaggcgagat cctgggtggt atggctgctg ttgaacaacc
     6181 ggaaaaaccg gctgctcagc ctaaaaagca gcagcgtaaa ggccgtaaat aaggagcgtc
     6241 gctgatgtta caaccaaagc gtacaaaatt ccgtaaaatg cacaaaggcc gtaaccgcgg
     6301 tctggcgcag ggtacggatg ttagcttcgg cagcttcggt ctgaaagctg ttggccgtgg
     6361 tcgtctgact gcccgtcaga tcgaagcagc acgtcgtgct atgacccgtg cagttaagcg
     6421 tcaaggtaag atctggatcc gtgtgttccc ggacaaaccg atcactgaaa agccgctggc
     6481 agtgcgtatg ggtaaaggta aaggtaacgt ggagtattgg gttgccttga ttcagccggg
     6541 taaagtcctg tatgaaatgg acggtgttcc ggaagagctg gcccgtgaag cattcaagct
     6601 ggcagcagcg aaactgccga ttaaaaccac ctttgtaact aagacggtga tgtaatgaaa
     6661 gcaaaagagc tgcgtgagaa gagcgttgaa gagctgaaca ccgagctgct gaacctgctg
     6721 cgtgagcagt tcaacctgcg tatgcaggct gcaagtggcc agctgcaaca gtctcacctg
     6781 ttgaagcaag tgcgtcgcga tgtcgcacgc gttaagactt tactgaacga gaaggcgggt
     6841 gcgtaatgac cgataaaatc cgtactctgc aaggtcgcgt tgttagcgac aaaatggaga
     6901 aatccattgt tgttgctatc gaacgttttg tgaaacaccc gatctacggt aaattcatca
     6961 agcgtacgac caaactgcac gtacatgacg agaacaacga atgcggtatc ggtgacgtgg
     7021 ttgaaatccg cgaatgccgt ccgctgtcca agactaaatc ctggacgctg gttcgcgttg
     7081 tagagaaagc ggttctgtaa tacagtacac tctctcaata cgaataaacg gctcagaaat
     7141 gagccgttta ttttttctac ccatatcctt gaagcggtgt tataatgccg cgccctcgat
     7201 atggggattt ttaacgacct gattttcggg tctcagtagt agttgacatt agcggagcac
     7261 taaaatgatc caagaacaga ctatgctgaa cgtcgccgac aactccggtg cacgtcgcgt
     7321 aatgtgtatc aaggttctgg gtggctcgca ccgtcgctac gcaggcgtag gcgacatcat
     7381 caagatcacc atcaaagaag caattccgcg tggtaaggtc aaaaaaggtg atgtgctgaa
     7441 ggcggtagtg gtgcgcacca agaagggtgt tcgtcgcccg gacggttctg tcattcgctt
     7501 cgatggtaat gcttgtgttc ttctgaacaa caacagcgag cagcctatcg gtacgcgtat
     7561 ttttgggccg gtaactcgtg agcttcgtag tgagaagttc atgaaaatta tctctctggc
     7621 accagaagta ctctaaggag cgaatcatgg cagcgaaaat ccgtcgtgat gacgaagtta
     7681 tcgtgttaac cggtaaagat aaaggtaaac gcggtaaagt taagaatgtc ctgtcttccg
     7741 gcaaggtcat tgttgaaggt atcaacctgg ttaagaaaca tcagaagccg gttccggccc
     7801 tgaaccaacc gggtggcatc gttgaaaaag aagccgctat tcaggtttcc aacgtagcaa
     7861 tcttcaatgc ggcaaccggc aaggctgacc gtgtaggctt tagattcgaa gacggtaaaa
     7921 aagtccgttt cttcaagtct aacagcgaaa ctatcaagta atttggagta gtacgatggc
     7981 gaaactgcat gattactaca aagacgaagt agttaaaaaa ctcatgactg agtttaacta
     8041 caattctgtc atgcaagtcc ctcgggtcga gaagatcacc ctgaacatgg gtgttggtga
     8101 agcgatcgct gacaaaaaac tgctggataa cgcagcagca gacctggcag caatctccgg
     8161 tcaaaaaccg ctgatcacca aagcacgcaa atctgttgca ggcttcaaaa tccgtcaggg
     8221 ctatccgatc ggctgtaaag taactctgcg tggcgaacgc atgtgggagt tctttgagcg
     8281 cctgatcact attgctgtac ctcgtatccg tgacttccgt ggcctgtccg ctaagtcttt
     8341 cgacggtcgt ggtaactaca gcatgggtgt ccgtgagcag atcatcttcc cagaaatcga
     8401 ctacgataaa gtcgaccgcg ttcgtggttt ggatattacc attaccacta ctgcgaaatc
     8461 tgacgaagaa ggccgcgctc tgctggctgc ctttgacttc ccgttccgca agtaaggtag
     8521 ggttactaaa tggctaagca atcaatgaaa gcacgcgaag taaaacgcgt agctttagct
     8581 gataaatact tcgcgaaacg cgctgaactg aaagcgatca tctctgatgt gaacgcttcc
     8641 gacgaagatc gttggaacgc tgttctcaag ctgcagactc tgccgcgtga ttccagcccg
     8701 tctcgtcagc gtaaccgctg ccgtcaaaca ggtcgtccgc atggtttcct gcggaagttc
     8761 gggttgagcc gtattaaggt ccgtgaagcc gctatgcgcg gtgaaatccc gggtctgaaa
     8821 aaggctagct ggtaattgtc accaattgaa tcacgggagt aaagacagat gagcatgcaa
     8881 gatccgatcg cggatatgct gacccgtatc cgtaacggtc aggccgcgaa caaagctgcg
     8941 gtcaccatgc cttcctccaa gctgaaagtg gcaatcgcca acgtgctgaa ggaagaaggt
     9001 tttattgaag attttaaagt tgaaggcgac accaagcctg aactggaact tactctgaag
     9061 tatttccagg gcaaagctgt tgtagaaagc attcagcgtg tcagccgccc aggtctgcgc
     9121 atctataaac gtaaagatga gctgccgaaa gttatggcgg gtctgggtat cgcagttgtt
     9181 tctacctcta aaggtgttat gactgatcgt gcagcgcgcc aggctggtct tggtggcgaa
     9241 attatctgct acgtagccta atcggaggaa aaaatgtctc gtgttgctaa agcaccggtc
     9301 gttgttcctg ccggcgttga cgtaaaaatc aacggtcagg ttattacgat caaaggtaaa
     9361 aacggcgagc tgactcgtac tctcaacgat gctgttgaag ttaaacatgc agataatacc
     9421 ctgaccttcg gtccgcgtga tggttacgca gacggttggg cacaggctgg taccgcgcgt
     9481 gccctgctga actcaatggt tatcggtgtt accgaaggct tcactaagaa gctgcagctg
     9541 gttggtgtag gttaccgtgc agcggttaaa ggcaatgtga ttaacctgtc tctgggtttc
     9601 tctcatcctg ttgaccatca gctgcctgcg ggtatcactg ctgaatgtcc gactcagact
     9661 gaaatcgtgc tgaaaggcgc tgataagcag gtgatcggcc aggttgcagc ggatctgcgc
     9721 gcctaccgtc gtcctgagcc ttataaaggc aagggtgttc gttacgccga cgaagtcgtg
     9781 cgtaccaaag aggctaagaa gaagtaaggt aacactatgg ataagaaatc tgctcgtatc
     9841 cgtcgtgcga cccgcgcacg ccgcaagctc caggagctgg gcgcaactcg cctggtggta
     9901 catcgtaccc cgcgtcacat ttacgcacag gtaattgcac cgaacggttc tgaagttctg
     9961 gtagctgctt ctactgtaga aaaagctatc gctgaacaac tgaagtacac cggtaacaaa
    10021 gacgcggctg cagctgtggg taaagctgtc gctgaacgcg ctctggaaaa aggcatcaaa
    10081 gatgtatcct ttgaccgttc cgggttccaa tatcatggtc gtgtccaggc actggcagat
    10141 gctgcccgtg aagctggcct tcagttctaa ggtagaggtg taagatggct cacatcgaaa
    10201 aacaagctgg cgaactgcag gaaaagctga tcgcggtaaa ccgcgtatct aaaaccgtta
    10261 aaggtggtcg tattttctcc ttcacagctc tgactgtagt tggcgatggt aacggtcgcg
    10321 ttggttttgg ttacggtaaa gcgcgtgaag ttccagcagc gatccagaaa gcgatggaaa
    10381 aagcccgtcg caatatgatt aacgtcgcgc tgaataacgg cactctgcaa caccctgtta
    10441 aaggtgttca cacgggttct cgcgtattca tgcagccggc ttccgaaggt accggtatca
    10501 tcgccggtgg tgcaatgcgc gccgttctgg aagtcgctgg ggttcataac gttctggcta
    10561 aagcatatgg ttccaccaac ccgatcaacg tggttcgtgc aactattgat ggcctggaaa
    10621 atatgaattc tccagaaatg gtcgctgcca agcgtggtaa atccgttgaa gaaattctgg
    10681 ggaaataaac catggcaaag actattaaaa ttactcaaac ccgcagtgca atcggtcgtc
    10741 tgccgaaaca caaggcaacg ctgcttggcc tgggtctgcg tcgtattggt cacaccgtag
    10801 agcgcgagga tactcctgct attcgcggta tgatcaacgc ggtttccttc atggttaaag
    10861 ttgaggagta agagatgcgt ttaaatactc tgtctccggc cgaaggctcc aaaaaggcgg
    10921 gtaaacgcct gggtcgtggt atcggttctg gcctcggtaa aaccggtggt cgtggtcaca
    10981 aaggtcagaa atctcgttct ggcggtggcg tacgtcgcgg tttcgagggt ggtcagatgc
    11041 ctctgtaccg tcgtctgccg aaattcggct tcacttctcg taaagcagcg attacagccg
    11101 aagttcgtct gtctgacctg gctaaagtag aaggcggtgt tgtagacctg aacacgctga
    11161 aagcggctaa cattatcggt atccagatcg agttcgcgaa agtgatcctg gctggcgaag
    11221 taacgactcc ggtaactgtt cgtggcctgc gtgttactaa aggcgctcgt gctgctatcg
    11281 aagctgctgg cggtaaaatc gaggaataag tagcagatgg ctaaacaacc gggattagat
    11341 tttcaaagtg ccaaaggtgg cttaggcgag ctgaaacgca gactgctgtt tgttatcggt
    11401 gcgctgattg tgttccgtat tggctctttt attccgatcc ctggtattga tgccgctgta
    11461 cttgccaaac tgcttgagca acagcgaggc accatcattg agatgtttaa catgttctct
    11521 ggtggtgctc tcagccgtgc ttctatcttt gctctgggga tcatgccgta tatttcggcg
    11581 tcgatcatta tccagctgct gacggtggtt cacccaacgt tggcagaaat taagaaagaa
    11641 ggggagtctg gtcgtcgtaa gatcagccag tacacccgtt acggtactct ggtgctggca
    11701 atattccagt cgatcggtat tgctaccggt ctgccgaata tgcctggtat gcaaggcctg
    11761 gtgattaacc caggctttgc attctacttc accgctgttg taagtctggt cacaggaacg
    11821 atgttcctga tgtggttggg cgaacagatt actgaacgag gtatcggcaa cggtatttca
    11881 atcattatct tcgccggtat tgtcgcggga ctcccgccag ccattgccca tactatcgag
    11941 caagcgcgtc aaggcgacct gcacttcctc gtgttgctgt tggttgcagt attagtattt
    12001 gcagtgacgt tctttgttgt atttgttgag cgtggtcaac gccgcattgt ggtaaactac
    12061 gcgaaacgtc agcaaggtcg tcgtgtctat gctgcacaga gcacacattt accgctgaaa
    12121 gtgaatatgg cgggggtaat cccggcaatc ttcgcttcca gtattattct gttcccggcg
    12181 accatcgcgt catggttcgg gggcggtact ggttggaact ggctgacaac aatttcgctg
    12241 tatttgcagc ctgggcaacc gctttatgtg ttactctatg cgtctgcaat catcttcttc
    12301 tgtttcttct acacggcgtt ggttttcaac ccgcgtgaaa cagcagataa cctgaagaag
    12361 tccggtgcat ttgtaccagg aattcgtccg ggagagcaaa cggcgaagta tatcgataaa
    12421 gtaatgaccc gcctgaccct ggttggtgcg ctgtatatta cctttatctg cctgatcccg
    12481 gagttcatgc gtgatgcaat gaaagtaccg ttctacttcg gtgggacctc actgcttatc
    12541 gttgttgtcg tgattatgga ctttatggct caagtgcaaa ctctgatgat gtccagtcag
    12601 tatgagtctg cattgaagaa ggcgaacctg aaaggctacg gccgataatt ggtcgcccga
    12661 gaagttacgg agagtaaaaa tgaaagttcg tgcttccgtc aagaaattat gccgtaactg
    12721 caaaatcgtt aagcgtgatg gtgtcatccg tgtgatttgc agtgccgagc cgaagcataa
    12781 acagcgccaa ggctgatttt ttcgcatatt tttcttgcaa agttgggttg agctggctag
    12841 attagccagc caatcttttg tatgtctgtg cgtttccatt tgagtatcct gaaaacgggc
    12901 ttttcagcat ggaacgtaca tattaaatag taggagtgca tagtggcccg tatagcaggc
    12961 attaacattc ctgatcataa gcatgccgta atcgcattaa cttcgattta tggcgtcggc
    13021 aagacccgtt ctaaagccat cctggctgca gcgggtatcg ctgaagatgt taagatcagt
    13081 gagctgtctg aaggacaaat cgacacgctg cgtgacgaag ttgccaaatt tgtcgttgaa
    13141 ggtgatctgc gccgtgaaat cagcatgagc atcaagcgcc tgatggatct tggttgctat
    13201 cgcggtttgc gtcatcgtcg tggtctcccg gttcgcggtc agcgtaccaa gaccaacgca
    13261 cgtacccgta agggtccgcg caaaccgatc aagaaataat cggggtgatt gaataatggc
    13321 aaaggcacca attcgtgcac gtaaacgtgt aagaaaacaa gtctctgacg gcgtggctca
    13381 tatccatgct tctttcaaca acaccatcgt gactatcact gatcgtcagg gtaacgcgtt
    13441 gggttgggca acagccggtg gttccggttt ccgtggttct cgcaaatcca ctccgtttgc
    13501 agctcaggtt gcagcagagc gttgcgctga cgccgtgaaa gaatacggca tcaagaatct
    13561 ggaagttatg gttaaaggtc cgggtccagg ccgcgaatct actattcgtg ctctgaacgc
    13621 cgcaggtttc cgcatcacta acattactga tgtgactccg atccctcata acggttgtcg
    13681 tccgccgaaa aaacgtcgcg tataacgcct cgttttccag gtttgttgga gaaagaaaat
    13741 ggcaagatat ttgggtccta agctcaagct gagccgtcgt gagggcaccg acttattcct
    13801 taagtctggc gttcgcgcga tcgataccaa gtgtaaaatt gaacaagctc ctggccagca
    13861 cggtgcgcgt aaaccgcgtc tgtctgacta tggtgtgcag ttgcgtgaaa agcaaaaagt
    13921 tcgccgtatc tatggtgtgc tggagcgtca gttccgtaac tactacaaag aagcagcacg
    13981 tctgaaaggc aacaccggtg aaaacctgtt ggctctgctg gaaggtcgtc tggacaacgt
    14041 tgtataccgt atgggcttcg gtgccactcg tgcagaagca cgtcagctgg ttagccataa
    14101 agcaattatg gtaaacggtc gtgttgttaa catcgcttct tatcaggtta gtccgaatga
    14161 cgttgtaagc attcgtgaga aagcgaagaa gcagtctcgc gtgaaagccg ctctggagct
    14221 ggctgagcag cgtgaaaagc caacctggct ggaagttgat gctggcaaga tggaaggtac
    14281 gtttaagcgt aagccggagc gttctgatct gtctgcggac attaacgaac acctgatcgt
    14341 cgagctttac tccaagtaaa gcttagtacc aaagagagga cacaatgcag ggttctgtga
    14401 cagagtttct aaaaccgcgc ctggttgata tcgagcaagt gagttcgacg cacgccaagg
    14461 tgacccttga gcctttagag cgtggctttg gccatactct gggtaacgca ctgcgccgta
    14521 ttctgctctc atcgatgccg ggttgcgcgg tgaccgaggt tgagattgat ggtgtactac
    14581 atgagtacag caccaaagaa ggcgttcagg aagatatcct ggaaatcctg ctcaacctga
    14641 aagggctggc ggtgagagtt cagggcaaag atgaagttat tcttaccttg aataaatctg
    14701 gcattggccc tgtgactgca gccgatatca cccacgacgg tgatgtcgaa atcgtcaagc
    14761 cgcagcacgt gatctgccac ctgaccgatg agaacgcgtc tattagcatg cgtatcaaag
    14821 ttcagcgcgg tcgtggttat gtgccggctt ctacccgaat tcattcggaa gaagatgagc
    14881 gcccaatcgg ccgtctgctg gtcgacgcat gctacagccc tgtggagcgt attgcctaca
    14941 atgttgaagc agcgcgtgta gaacagcgta ccgacctgga caagctggtc atcgaaatgg
    15001 aaaccaacgg cacaatcgat cctgaagagg cgattcgtcg tgcggcaacc attctggctg
    15061 aacaactgga agctttcgtt gacttacgtg atgtacgtca gcctgaagtg aaagaagaga
    15121 aaccagagtt cgatccgatc ctgctgcgcc ctgttgacga tctggaattg actgtccgct
    15181 ctgctaactg ccttaaagca gaagctatcc actatatcgg tgatctggta caacgtaccg
    15241 aggttgagct ccttaaaacg cctaaccttg gtaaaaaatc tcttactgag attaaagacg
    15301 tgctggcttc ccgtggactg tctctgggca tgcgcctgga aaactggcca ccggcaagca
    15361 tcgctgacga gtaaccggat cacaggttaa ggttttactg agaaggataa ggtcatgcgc
    15421 catcgtaaga gtggtcgtca actgaaccgc aacagcagcc atcgccaggc tatgttccgc
    15481 aatatggcag gttcactggt tcgtcatgaa atcatcaaga cgactctgcc taaagcgaaa
    15541 gagctgcgcc gcgtagttga gccgctgatt actcttgcca agactgatag cgttgctaat
    15601 cgtcgtctgg cattcgcccg tactcgtgat aacgagatcg tggcaaaact gtttaacgaa
    15661 ctgggcccgc gtttcgcgag ccgtgccggt ggttacactc gtattctgaa gtgtggcttc
    15721 cgtgcaggcg acaacgcgcc gatggcttac atcgagctgg ttgatcgttc agagaaagca
    15781 gaagctgctg cagagtaatc tgaagcaacg taaaaaaacc cgccccggcg ggttttttta
    15841 tacccgtagc atccccactt atctacaata gctgtactct ttttgttcat cccctggagt
    15901 atttatgtgg ttacttgacc agtgggcaga gcgtcatata gcagaagcgc aagcgaaagg
    15961 tgagtttgat aacctggcag gtagcggcga accattgata ctggatgatg attctcacgt
    16021 gccaccggaa ttacgtgcgg ggtatcgctt gctgaagaat gccggttgct taccgccaga
    16081 acttgagcaa cggagagaag caattcagct tctggatatc ctgagaggta tccgtcacga
    16141 tgatccgcaa tatcaagagg ttagccgtcg attgtcatta ctggaattga agctgcgaca
    16201 agctggattg agtaccgatt ttttacgcgg cgattatgct gacaagttgt tggacaaaat
    16261 caacgataac tagtggagta tgtatgtatc gcattggtga gctggcaaaa atggcggaag
    16321 taacacctga cacgattcgt tattacgaaa aacagcagat gatggagcat gaagtgcgta
    16381 ctgaaggcgg gtttcgcctg tataccgaaa gcgatctcca gcgattgaaa tttatccgcc
    16441 atgccagaca actaggtttc agtctggagt cgatccgcga gttgctgtcg atccgcatcg
    16501 atcctgaaca ccatacctgt caggagtcaa aaggcattgt gcaggaaaga ttgcaggaag
    16561 tcgaagcacg gatagccgag ttgcagagta tgcagcgttc cttgcaacgc cttaacgatg
    16621 cctgttgtgg gaccgcccat agcagtgttt attgttcgat tcttgaagct cttgaacaag
    16681 gggcgagtgg cgttaagagt ggctgttgat tttttgcact ggcaggatta cactcgcgcc
    16741 gtaaaataac caattggagt ttttatgagc cgatatcagc atactaaagg gcagataaag
    16801 gataatgcga tagaagcatt actacatgat cccttattcc gacagcgcgt agagaaaaat
    16861 aagaagggga aaggcagtta catgcgaaaa ggaaaacatg gcaatcgggg gaactgggag
    16921 gccagtggca agaaagtaaa tcactttttt accactggcc ttctgctttc aggcgtttgt
    16981 taagagcggt tattctgctc tttcagcaaa tcacgaattt ctgtcagtaa tacttcttct
    17041 ttagttggtg ctggtgcggc tgctggttct tcttttttcc gattcagttt gttgattagc
    17101 ttaatcgcca taaagatggc aaaggccaca atcagaaaat caaagacgtt ttgaatgaag
    17161 acaccgtaat gcatcacaac agcagggata tccccctgcg catcgcgtag cgtgacagca
    17221 aactgtttaa agtcgatccc gccaattaat aagcccagag gtggcatgat gatatcggca
    17281 accagtgaag atacaatctt cccgaatgcc gcaccgataa tgacacccac cgccaaatcc
    17341 accacgttcc cgcgcatcgc aaattcgcga aattctttaa taatgctcat gttattctcc
    17401 ctatgaagcc gacaaccata agtctaacaa atgttaagcc attttcctgc taggaatgaa
    17461 tttaattaat ccttgataat caaagggaaa taataaggcg tcattagacg ccttattaat
    17521 tacaagaaga aagggcttgg ctggaagagt ctttcgacgt cggtaataaa ctttttatct
    17581 gtgaggaaca taattacgtg atcgccttgc tcaatgcgca gattgtcatt ggcaatcatc
    17641 acgtcgtttc cacgtaccac cgctccaata atcgttcctg gcggtagctt gatttcgtca
    17701 atgactctgc cgacaacgcg tgaggtgctt tcatcaccgt gagcaacggc ttcaatagct
    17761 tctgctacgc cgcggcgcaa tgaggaaaca ccaacaatat ctgcttttcg cacatggcta
    17821 agcaacgcag aaatagttgc ttgttgtggt gaaatcgcaa tatcgatcac gctcccctga
    17881 accagatcca cataagcgcg acgctggatc aataccatca cctttttcgc acccatacgt
    17941 ttggcaagca tggcggacat gatattggcc tcgtcatcgt tggtgacggc aataaacaga
    18001 tcaacttgat cgatatgttc ttcggccagc agttcttgat ccgacgcatc accaaaaaag
    18061 acgatcgtat tctgcaactt ttccgccagt tcggcagcgc gctgctgatt acgttcgatg
    18121 agtttaacgc tgtaatcttt ttccagacga cgcgccagcc ctgcaccgat attaccgcca
    18181 ccaaccagca tgatccgctt atacggtttt tccagtcgct gtaattcact catcaccgca
    18241 cggatatgct gtgaagcggc aataaagaac acttcatcac cagcttccac aatggtcgaa
    18301 ccttgtggac gaatggggcg atcgtggcgg aaaattgctg ccacacgagt atcgatatgt
    18361 ggcatatgtt cgcgcatggt cgaaagtgcg ttaccaatca gcgggccgcc ataataggct
    18421 ttaaccacag cgaggctgac tttaccctca gcgaagttca ccacctgcaa tgcgccggga
    18481 tactcaatca gtcggtaaat attatcgata accaactgct ctggtgcgat cagatgatca
    18541 atcggtacag catctgaatg aaatagctta tcggcatcgc gcacgtagtc tggtgagcgg
    18601 atgcgagcga tgcgattagg ggtgttgaaa agtgagtagg ctacctggca ggcaaccata
    18661 ttggtttcat ctgaactggt tacagcaacc agcatatcgg cgtcgtcggc acctgcctcc
    18721 cgcaatacgc gtggatgaga gccatgcccc tgcacgactc gcaggtcaaa tttatcctgc
    18781 aaggtccgca gacgctcacc gttggtatcg acaacagtga tatcgttgtt ctcgccaacc
    18841 aggttttccg ccagtgtgcc gccaacctgg ccggcaccca gaatgataat tttcatcagt
    18901 cgcgacccgt tatctcatca ctttttgatt agcttagcgt aaaagaagcc gtcgccctct
    18961 tcggcaccag gcagattttg tttacccggt tgctctggtg ttcctgtttc gcaaagttcg
    19021 gcatcagcgg tacgttgcaa aaaggcttta atctgcaggc tattctcttc cggtaacacc
    19081 gaacaggtgg catagaccag ggttccaccg gattttaaat gcggccaaat ggcgtcgaga
    19141 atttcagact gcaattgcgc gagttccggg atatcgcgat cgcgacgtaa ccatttaata
    19201 tccggatggc gacgaatcac accggttgct gaacaaggcg catctaataa aatgcgatca
    19261 aactgttgct cgccacacca ttgggaaggg tagcggccat caccttgttt cacggtcgct
    19321 ttcataccaa ggcgttttaa attgtcgtaa acgcgagaga ggcgctgttc gtcaatatca
    19381 accgcaacaa cctgcgcttc tggtgccacc tcaaggatat gcgttgtttt accgccgggg
    19441 gcggcacaaa gatccaaaat gtgttcaccg ttttgtggcg caagccaggt catgcaacct
    19501 tgtgctgatg catcctgaac ggtaacccat ccgtcttcaa aaccaggtag cgcatgaaca
    19561 ggtgcaggtg tttccagccg tacagcatca gggtaatccg catgcgggaa acctttcatt
    19621 cctgcttcat ccaacaatgc aagccagctg tcgcgggaat gatgcgtacg attaacgcgc
    19681 agccacattg gcggacgctg gttattggct tcgacgatgg attgccactg ctctggatac
    19741 gctttttgca gacgcttcag caaccaggaa ggatgcagat aacgtgcatc actggcatta
    19801 aactcggcta ataactcttc ttgctgacgc tggaactggc gtaatacacc gtttatcaac
    19861 cctttaagtt gcggacgctt aattgcgata gcgccttcaa ccgtttcagc cagcgcagca
    19921 tgaggtggaa tgcgggtata aagcagttga tacaaaccaa ccataatcag gtaatgcacg
    19981 gtccgctgtt tgccggtcat cggacgggcc attaacttat taatcagcca gtctaactgc
    20041 gaaagcgtac gcagtacgcc aaagcacaac tcttgaagaa gtgctttgtc tttatcggaa
    20101 actttttgct ggagcggtgg cagaatgttg cttaatgatt gcccttgctc gacgacttgt
    20161 tcaacggcct gggccgccat gctacgtaaa ttacgttgtt ttttcataag tataaaaacg
    20221 cccggcaaga ccgggcttag aagagtggac aatcagacca gacggttgcc cggaacaaac
    20281 cattcccgac gagagttcag gaggtcttgc gcgctcatcg ctttcttacc cgcaggttgt
    20341 aacgagagca ggttcaggat gccatcacca gtcgcaacct gaatgccttg tttgttggct
    20401 tcaaggatcg ttcctggtgc agcgttggtt gccgtatcaa tgaccgatgc tttccagact
    20461 ttaaccggct gtccttcaat ttccagccag ctcattggcc atggattgaa agcgcgaatg
    20521 cagcgttcaa gctgtgctgc cgaaagtgac cagtcaatac gcgcttcttc tttactcaac
    20581 ttttcggcgt aagtgacaag agtttcgtcc tgaacttctg gtttcgccgt gccgtctgcc
    20641 agttgtttta acgtggtgat aagcccttgt gggccaagct ctgccagctt gtcgtacagc
    20701 gtaccactgg tatcttctgc agtaatcggg caggagagct tatagagcat gtcaccggtg
    20761 tctaaaccaa catccatttg cataatggtc acaccagttt ctgcatcacc cgcccatagt
    20821 gagcgttgga ttggtgcagc accgcgccag cgtggcagca gtgaaccatg aacgttgata
    20881 cagccaagac gcggcatctc cagcacagct ttaggcagaa ttaaaccata ggcgacgacg
    20941 accataacat cagcctgcag atcggcgacc agttgctggt tttcttgtgg acgcagggaa
    21001 acaggttgaa aaacgggcag acctttttcc tcagccagaa ctttaatcgg gctgggcatc
    21061 agttttttac cgcgtcctgc cggtcggtct ggctgggtga acacgccaac gacgttatga
    21121 ccagaagaca acagcgcgtc gagatgacgc gctgcaaagt caggtgtacc cgcaaaaata
    21181 atacgtagtg attctgacac gttagttctt atccttaagc ccgggctttc agacgatcca
    21241 gtttttcaac tttctgacga atacgttgtt gtttcaacgg tgacagataa tccataaaca
    21301 gtttgccgac caggtgatcc atctcatgct gaatacagat ggctaacaga ccgtctgctt
    21361 ccagttcaaa tggtttaccg tcgcggtcaa gggcgcaaat tttaactttc tctgcgcgcg
    21421 gcactaaagc acgttgttca gggatcgaca ggcaaccttc ttcaatgcct gtttcgccgc
    21481 ttttttctaa aagctctgga ttgattaaca ctagccgttc gtcacggttt tccgaaacat
    21541 caataacaat gatacgttga tggatatcaa cctgggttgc cgccaggcca ataccttctt
    21601 ctgcgtacat cgtctcgaac atatcatcga cgatacgctg aatttctgca ttcacttctt
    21661 ctaccggttt agcaactttg cgaagccgct cgtccggaat atgtaacact tgcaaaactg
    21721 acataaatct ccagagatgt gttcaggagt tagaaagatt atttcttcta ttctagacaa
    21781 atccccctct gattgacagc atcactgacc aatcgcaaag attgctaagg ctgcttatgg
    21841 cagggagata aggatggtcg atacagaaat ttggctgcgt ttaatgagta tcagcagctt
    21901 gtacggcgat gatatggtcc gtatagctca ctggctggca aaacagtcgc aaattgatgc
    21961 ggttggattg cagcaaacag ggcttacatt gcggcaggca caacgctttc tttcatttcc
    22021 gcgaaagagt atcgaaagct cactttgttg gttggagcaa cccaaccatc atttaatccc
    22081 tgcggacagc gaattttatc ctcctcaact tctggtgacg acagattacc ccggcgcact
    22141 gtttgttgaa ggagaactgc acgcgctgca ttcatttcag cttgccgtag tggggagtcg
    22201 ggcgcattca tggtatggcg agcgatgggg acggttattt tgcgaaactc tggcgacgcg
    22261 tggagtgaca attacgagtg gactggcgcg tggaatcgat ggtgtggcgc ataaagctgc
    22321 cttacaggta aatggcgtca gcattgctgt attggggaat ggacttaata ccattcatcc
    22381 ccgccgccat gcccgactgg ctgccagtct gcttgaacag gggggcgctc tcgtctcgga
    22441 atttcccctc gatgttccac cccttgctta caatttccca cgaagaaatc gcattatcag
    22501 tggtctaagt aaaggtgtac tggtggtgga agcggctttg cgtagtggtt cgctggtgac
    22561 agcacgttgt gcgcttgagc aggggcgaga agtttttgcc ttgccaggtc caatagggaa
    22621 tccgggaagc gaagggcctc actggttaat aaaacaaggt gcgattcttg tgacggaacc
    22681 ggaagaaatt ctggaaaact tgcaatttgg attgcactgg ttgccagacg cccctgaaaa
    22741 ttcattttat tcaccagatc agcaagacgt ggcattgcca tttcctgagc tcctggctaa
    22801 cgtaggagat gaggtaacac ctgttgacgt cgtcgctgaa cgtgccggcc aacctgtgcc
    22861 agaggtagtt actcaactac tcgaactgga gttagcagga tggatcgcag ctgtacccgg
    22921 cggctatgtc cgattgagga gggcatgcca tgttcgacgt actaatgtat ttgtttgaaa
    22981 cctatattca cacagaagct gagttgcgtg tggatcaaga caaacttgaa caggatctta
    23041 ccgacgcagg ttttgagcga gaagatatct acaatgccct gctatggctg gaaaaacttg
    23101 ctgattatca ggaagggttg gcagaaccga tgcaactggc ctcggatcct ctctccatgc
    23161 gtatttatac accggaagag tgtgaacgac tggatgccag ctgccgtggg tttctgcttt
    23221 tccttgagca gattcaggtg ctcaaccttg aaactcgtga aatggtgata gagcgagtgc
    23281 tcgcgctgga taacgcagag ttcgaactgg atgatctgaa atgggtgatc ctgatggtgt
    23341 tgttcaatat tccgggctgc gaaaatgcgt accagcaaat ggaagaatta ctctttgaag
    23401 tgaatgaagg tatgctgcat taatcatttc tttaattcag cataagttgt tatggcgaaa
    23461 tcagcactgt tcacggtgcg taataatgag tcctgcccaa agtgcggggc tgaactggtt
    23521 attcgatccg ggaaacacgg tccgtttctt ggatgctcac agtatccggc gtgtgactac
    23581 gtccgtcctc tgaaatcttc agcggatgga catatcgtca aagttctgga ggggcaggtt
    23641 tgccctgcat gtggcgcaaa tctggtatta cgccagggac gctttggtat gtttattggt
    23701 tgcattaact accctgaatg cgaacatacc gaacttatcg ataaaccgga cgaaacagca
    23761 attacatgcc cccaatgtcg gacgggccat ctggtccagc gccgctcccg ttatggcaaa
    23821 acatttcact cttgtgatcg ctacccggag tgtcaatttg ccattaactt caaacccata
    23881 gctggagaat gccctgagtg tcattatccg ctactcatcg aaaagaaaac cgcgcagggt
    23941 gtaaaacact tttgtgccag taaacaatgt ggaaagccgg tttcggcgga ataataacgt
    24001 gaataataac ctgcaaggag acgctatcgc agctgcgata gatgtcctca atgaagaacg
    24061 tgtcatcgcc tatccaacgg aagccgtttt cggtgtcggg tgcgatcctg atagcgaaac
    24121 agcagtgatg cgactgttgg agttaaaaca gcgtccggtt gataaggggc tgattttaat
    24181 cgcggcaaat tacgagcagc ttaaacccta tattgatgac accatgctga ctgatgcgca
    24241 gcgtgaaacc attttttccc gctggccagg tcctgtcacc tttgtctttc ccgcgcctgc
    24301 gacaacaccg cgctggttga cgggccgctt tgattcgctt gctgtacgag tcaccgacca
    24361 tccgttggtg gttgctttgt gccaggctta tggtaaaccg ctggtttcta ccagtgccaa
    24421 cttgagtgga ttgccacctt gtcgaacagt agacgaagtt cgcgcacaat ttggcgcggc
    24481 gttcccggtt gtgcctggtg aaacgggggg gcgtttaaat ccttcagaaa tccgcgatgc
    24541 cctgacgggt gaactgtttc gacaggggta acataatgga aacctatgct gtttttggta
    24601 atccgatagc ccacagcaaa tcgccattca ttcatcagca atttgctcag caactgaata
    24661 ttgaacatcc ctatgggcgc gtgttggcac ccatcaatga tttcatcaac acactgaacg
    24721 ctttctttcg tgctggtggt aaaggtgcga atgtgacggt gccttttaaa gaagaggctt
    24781 ttgccagagc ggatgagctt actgaacggg cagcgttggc tggtgctgtt aataccctca
    24841 agcggttaga agatggacgc ctgctgggtg acaataccga tggtataggt ttgttaagcg
    24901 atctggaacg tctgtctttt atccgtcctg gtttacgtat tctgctcatc ggcgctggtg
    24961 gagcatctcg cggcgtacta ctgccacttc tttccctgga ctgtgcggtg acaatcacta
    25021 atcggacggt atcccgcgcg gaagagttgg ctaaattgtt tgcgcacact ggcagtattc
    25081 aggcgttggg tatggacgaa ctggaaggtc atgagtttga tctcattatt aatgcaacat
    25141 ccagtggcat cagtggtgat attccggcga tcccgtcatc gctcattcat ccaggcattt
    25201 attgctatga catgttctat cagaaaggaa aaactccttt tctggcatgg tgtgagcagc
    25261 gaggctcaaa gcgtaatgct gatggtttag gaatgctggt ggcacaggcg gctcatgcct
    25321 ttcttctctg gcacggtgtt ctgcctgacg tagaaccagt tataaagcaa ttgcaggagg
    25381 aattgtccgc gtgaatcagg ccatccagtt tccggacaga gaagagtggg acgagaataa
    25441 aaaatgtgta tgttttcccg ctctcgtgaa tggcatgcaa ctgacatgtg cgatctctgg
    25501 cgagagtctg gcgtatcgtt ttactggaga tacgccagaa cagtggttag cgagttttcg
    25561 tcagcatcgc tgggatctgg aagaagaagc ggaaaactta attcaggaac aaagtgaaga
    25621 tgatcaaggc tgggtctggt taccctgatc cagatattcg tccttccatt tcacgtaatt
    25681 attcgcggaa tagcgtaacc cagccttctc ttcatcactt aacgggcgga tctgtttgac
    25741 ggggctaccg agatacagat atccgctctc cagccgttta ttttgtggga ccagactacc
    25801 cgcaccaatc atcacatcat cttctactat tgcgccatca agtaaaattg agcccatccc
    25861 aaccaaaact cgattgccaa tggtgcagcc gtggagcatc accttgtgac caacagtgac
    25921 atcttcgcca atggttaatg ggttgccatc tgggttgtac gaggatttat gagtgacatg
    25981 caacatactg ccatcctgga tattggtgcg tgctccgatc tgtacataat gtacatctcc
    26041 acgaatcaca acgagcggcc agatccccac atcatcagcc agacgaacgt caccaatcac
    26101 gacactgcta tcgtcgatca ttacgcgctg accgatttgt ggaaaaagat cgcggtatgg
    26161 gcgtaaaaca tcagacatac ttacctcagc aataaatgat ttactaatga ctttgggggc
    26221 attattggcc ttgtgcaagt cttttagtat gcaaaaaagc accgttttgt gtgcgaatgc
    26281 agcaaaaagg gtgaaaaaac aacaaacaga aaaaaagatc aaaaaagtac ttgtgcaaaa
    26341 aattgggatc cctataatgc gcctccgttg agacgacaac gtgaaatact tcacaagatg
    26401 gtcgtaacaa cgaagagaaa aaatcctgaa attcagggtt gactctgaaa gaggaaagcg
    26461 taatatacgc cacctcgcga cagtgagctg aaagctgcgt cgc
//
LOCUS       DAPOAV010000061        26380 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.061, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000061 DAPOAV010000000
VERSION     DAPOAV010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26380
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.061"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(303..2336)
                     /gene="betT"
                     /locus_tag="RN951_002910"
     CDS             complement(303..2336)
                     /gene="betT"
                     /locus_tag="RN951_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline BCCT transporter BetT"
                     /protein_id="HDX2527883.1"
                     /translation="MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIG
                     RTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSWAAMLFA
                     AGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA
                     LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLN
                     YGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDKGIRVLSELNVALALGLILFVL
                     FMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWTLFFWAWWVAWSPFV
                     GLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHP
                     ERGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWL
                     RVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRE
                     SANRDTAPRPLGLQDRLSWKKRLSRLMNYPGTRYTKQMMETVCYPAMEEVAQELRLRG
                     AYVELKSLPPEEGQQLGHLDLLVHMGEEQNFVYQIWPQQYSVPGFTYRARSGKSTYYR
                     LETFLLEGSQGNDLMDYSKEQVITDILDQYERHLNFIHLHREAPGHSVMFPDA"
     gene            2465..3052
                     /gene="betI"
                     /locus_tag="RN951_002911"
     CDS             2465..3052
                     /gene="betI"
                     /locus_tag="RN951_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414847.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator BetI"
                     /protein_id="HDX2527884.1"
                     /translation="MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTG
                     IISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALPQGSAEQRLQAIVGGNFDETQVS
                     SAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFRRELPREQAQEAGYGLAAL
                     IDGLWLRAALSGKPLDKTRANSLTRHFITQHLPTD"
     gene            3066..4538
                     /gene="betB"
                     /locus_tag="RN951_002912"
     CDS             3066..4538
                     /gene="betB"
                     /locus_tag="RN951_002912"
                     /EC_number="1.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine-aldehyde dehydrogenase"
                     /protein_id="HDX2527885.1"
                     /translation="MSRMAEQQLYIHGGYTSATSGRTFETINPANGNVLATVQAAGRE
                     DVDRAVKSAQQGQKIWASMTAMERSRILRRAVDILRERNDELAKLETLDTGKAYSETS
                     TVDIVTGADVLEYYAGLIPALEGSQIPLRETSFVYTRREPLGVVAGIGAWNYPIQIAL
                     WKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGLPDGVFNVLPGVGAETGQYLTE
                     HPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIVFDDADLDLAADIAMM
                     ANFFSSGQVCTNGTRVFVPAKCKAAFEQKILARVERIRAGDVFDPQTNFGPLVSFPHR
                     DNVLRYIAKGKEEGARVLCGGDVLKGDGFDNGAWVAPTVFTDCSDDMTIVREEIFGPV
                     MSILTYESEDEVIRRANDTDYGLAAGIVTADLNRAHRVIHQLEAGICWINTWGESPAE
                     MPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMAKFQSIF"
     gene            4552..6222
                     /gene="betA"
                     /locus_tag="RN951_002913"
     CDS             4552..6222
                     /gene="betA"
                     /locus_tag="RN951_002913"
                     /EC_number="1.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline dehydrogenase"
                     /protein_id="HDX2527886.1"
                     /translation="MQFDYIIIGAGSAGNVLATRLTEDPNTSVLLLEAGGPDYRFDFR
                     TQMPAALAFPLQGKRYNWAYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNAL
                     DLDNWAQEPGLENWSYLDCLPYYRKAETRDMGENDYHGGDGPVSVTTSKPGVNPLFEA
                     MIEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPQGRRASTARGYLDQAKSRPNLTIRT
                     HAMTDHIIFDGKRAVGVEWLEGDSTIPTRATANKEVLLCAGAIASPQILQRSGVGNAE
                     LLAEFDIPLVHELPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPKIGAEWLFGG
                     TGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSP
                     SRGHVRIKSRDPHQHPAILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYRGREISP
                     GVECQTDEQLDEFVRNHAETAFHPCGTCKMGYDEMSVVDGEGRVHGLEGLRVVDASIM
                     PQIITGNLNATTIMIGEKIADMIRGQEALPRSTAGYFVANGMPVRAKK"
     gene            6435..7103
                     /locus_tag="RN951_002914"
     CDS             6435..7103
                     /locus_tag="RN951_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527887.1"
                     /translation="MREQIKQDIDLIEILFYLKKKIRVILFIMAICMAMVLLFLYINK
                     DNIKVIYSLKINQTTPGILVSCDSNNNFACQTTMTEDVIQRITTFFHTSPDVKNREIR
                     LEWSGDKRALPTAEEEISRVQASIIKWYASEYHNGRQVLDEIQTPSAINSELYTKMIY
                     LTRNWSLYPNGDGCVTISSPEIKNKYPAAICLALGFFLSIVISVMFCLVKKMVDEYQQ
                     NSGQ"
     gene            complement(7346..8041)
                     /locus_tag="RN951_002915"
     CDS             complement(7346..8041)
                     /locus_tag="RN951_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein C"
                     /protein_id="HDX2527888.1"
                     /translation="MDNRGEFLNNVAQALGRPLRLEPQAEDAPLNNYANERLTQLNQQ
                     QRCDAFIQFASDVMLTRCELTSEAKAAEAAIRLCKELGDQSVVISGDTRLEELGISER
                     LQQECNAVVWDPAKGAENISQAEQAKVGVVYAEYGLTESGGVVLFSAAERGRSLSLLP
                     EYSLFILRKSTILPRVAQLAEKLHQKAQAGERMPSCINIISGPSSTADIELIKVVGVH
                     GPVKAVYLIIEDC"
     gene            complement(8034..9461)
                     /locus_tag="RN951_002916"
     CDS             complement(8034..9461)
                     /locus_tag="RN951_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster-binding protein"
                     /protein_id="HDX2527889.1"
                     /translation="MSIKTSNTDFKTRIRQQIEDPIMRKAVANAQQRIGANRQKMVDE
                     LGHWEEWRDRAAQIRDHVLSNLDAYLYQLSEKVTQNGGHVYFARTKEDATRYILQVAQ
                     RKNARKVVKSKSMVTEEIGVNHVLQDAGIQVIETDLGEYILQLDQDPPSHVVVPAIHK
                     DRHQIRRVLHERLGYEGPETPEAMTLFIRQKIREDFLSAEIGITGCNFAVAETGSVCL
                     VTNEGNARMCTTLPKTHIAVMGMERIAPTFAEVDVLITMLARSAVGARLTGYNTWLTG
                     PREAGHVDGPEEFHLVIVDNGRSEVLASEFRDVLRCIRCGACMNTCPAYRHIGGHGYG
                     SIYPGPIGAVISPLLGGYKDFKDLPYACSLCTACDNVCPVRIPLSKLILRHRRVMAEK
                     GITAKAEQRAIKMFAYANSHPGLWKVGMMAGAHAASWFINGGKTPLKFGAISDWMEAR
                     DLPEADGESFRSWFKKHQAQEKKNG"
     gene            complement(9472..10191)
                     /locus_tag="RN951_002917"
     CDS             complement(9472..10191)
                     /locus_tag="RN951_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(Fe-S)-binding protein"
                     /protein_id="HDX2527890.1"
                     /translation="MNVNFFVTCIGDALKSRMARDSVLLLEKLGCRVNFPEKQGCCGQ
                     PAINSGYIKEAIPGMKNLIAALEDNDDPIISPAGSCTYAVKSYPTYLADEPEWASRAA
                     KVAARMQDLTSFIVNKLGVVDVGASLQGRAVYHPSCSLARKLGVKDEPLTLLKNVRGL
                     ELLTFAEQDTCCGFGGTFSVKMAEISGEMVKEKVAHLMEVRPEYLIGADVSCLLNISG
                     RLQREGQKVKVMHIAEVLMSR"
     gene            complement(10718..11572)
                     /gene="rclR"
                     /locus_tag="RN951_002918"
     CDS             complement(10718..11572)
                     /gene="rclR"
                     /locus_tag="RN951_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator RclR"
                     /protein_id="HDX2527891.1"
                     /translation="MDALSRLLMLNAPQGTIDKNCVLGSDWQLPHGAGELSVIRWHAL
                     TQGAAKLEMPTGEIFTLRPGNVVLLPQNSAHRLSHVDNESTCIVCGTLRLQHSARYFL
                     TSLPETLFLAPVNHSVEYNWLREAIPFLQQESRSAMPGVDALCSQICATFFTLAVREW
                     IAQVNTEKNILSLLLHPRLGAVIQQMLEMPGHAWTVESLASIAHMSRASFAQLFRDVS
                     GTTPLAVLTKLRLQIAAQMFSRETLPVVVIAESVGYASESSFHKAFVREFGCTPGEYR
                     ERVRQLAP"
     gene            11798..13123
                     /locus_tag="RN951_002919"
     CDS             11798..13123
                     /locus_tag="RN951_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414838.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridine nucleotide-disulfide oxidoreductase"
                     /protein_id="HDX2527892.1"
                     /translation="MNKYQAVIIGFGKAGKTLAVTLAKAGWRVALIEQSNAMYGGTCI
                     NIGCIPTKTLVHDAQQHTDFVRAIQRKNEVVNFLRNKNFHNLADMPNIDVIDGQAEFI
                     NNHSLRVHRPEGNLEIHGEKIFINTGAQTVVPPIPGITTTPGVYDSTGLLNLKELPGH
                     LGILGGGYIGVEFASMFANFGSKVTILEAASLFLPREDRDIADNIATILRDQGVDIIL
                     NAHVERISHHENQVQVHSEHAQLAVDALLIASGRQPATASLHPENAGIAVNERGAIVV
                     DKRLHTTADNIWAMGDVTGGLQFTYISLDDYRIVRDELLGEGKRSTDDRKNVPYSVFM
                     TPPLSRVGMTEEQARESGADIQVVTLPVAAIPRARVMNDTRGVLKAIVDNKTQRMLGA
                     SLLCVDSHEMINIVKMVMDAGLPYSILRDQIFTHPSMSESLNDLFSLVK"
     gene            13232..13468
                     /locus_tag="RN951_002920"
     CDS             13232..13468
                     /locus_tag="RN951_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414837.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDX2527893.1"
                     /translation="MFKKSVLFATLLSGVMAFSTNADDKIILKHISVSSVSASPTVLE
                     DTIADIARKYNASSWKVTSMRIDNNSTATAVLYK"
     gene            13480..14073
                     /gene="rclC"
                     /locus_tag="RN951_002921"
     CDS             13480..14073
                     /gene="rclC"
                     /locus_tag="RN951_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414835.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reactive chlorine species resistance protein
                     RclC"
                     /protein_id="HDX2527894.1"
                     /translation="MEKYLHLLSRGDKIGLTLIRLSIAIVFMWIGLLKFVPYEADSIT
                     PFVANSPLMSFFYEHPEDYKQYLTHEGEYKPEARAWQTANNTYGFSNGLGVVEVIIAL
                     LVLANPVNRWLGLLGGLMAFTTPLVTLSFLITTPEAWVPALGDAHHGFPYLSGAGRLV
                     LKDTLMLAGAVMIMADSAREILKQRSNESSSTLKTEY"
     gene            complement(14232..14360)
                     /locus_tag="RN951_002922"
                     /pseudo
     CDS             complement(14232..14360)
                     /locus_tag="RN951_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308365.3"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
     gene            14663..15514
                     /locus_tag="RN951_002923"
     CDS             14663..15514
                     /locus_tag="RN951_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308364.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX2527895.1"
                     /translation="MIRQKILQQLLEWIECNLEHPISIEDIAQKSGYSRRNIQLLFRN
                     FMHVPLGEYIRKRRLCRAAILVRLTAKSMLDIALSLHFDSQQSFSREFKKLFGCSPRE
                     YRHRDYWDLANIFPSFLIRQQQKTECRLINFPETPIFGNSFKYDIEVSNKSPDEEVKL
                     RRHHLARCMKNFKTDIYFVSTFEPSTKSVDLLTVETFAGTVCEYADMPKEWTTTRGLY
                     ASFRYEGNWENYPDWVRNIYLIELPARGLARVNGSDIERFYYNEDFVEKDGNDVVCEI
                     FIPVRPV"
     gene            complement(15654..19910)
                     /gene="fdeC"
                     /locus_tag="RN951_002924"
     CDS             complement(15654..19910)
                     /gene="fdeC"
                     /locus_tag="RN951_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001635811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intimin-like adhesin FdeC"
                     /protein_id="HDX2527896.1"
                     /translation="MSHYKTGHKQPRFRYSVLARCVAWANISVQVLFPLAVTFTPVMA
                     ARAQHAVQPRLSMGNTTVTADNNVEKNVASFAANAGTFLSSQPDSDATRNFITGMATA
                     KANQEIQEWLGKYGTARVKLNVDKDFSLKDSSLEMLYPIYDTPTNMLFTQGAIHRTDD
                     RTQSNIGFGWRHFSGNDWMAGVNTFIDHDLSRSHTRIGVGAEYWRDYLKLSANGYIRA
                     SGWKKSPDIEDYQERPANGWDIRAEGYLPAWPQLGASLMYEQYYGDEVGLFGKDKRQK
                     DPHAISAEVTYTPVPLLTLSAGHKQGKSGENDTRFGLEVNYRIGEPLAKQLDTDSIRE
                     RRVLAGSRYDLVERNNNIVLEYRKSEVIRIALPERIEGKGGQTLSLGLVVSKATHGLK
                     NVQWEAPSLLAEGGKITGQGSQWQVTLPAYRPGKDNYYAISAVAYDNKGNASKRVQTE
                     VVITGAGMSADRTALTLDGQSRIQMLANGNEQRPLVLSLRDAEGQPVTGTKDQIKTEL
                     AFKPAGNIVTRSLKATKSQAKPTLGEFTETEAGVYQSVFTTGTQSGEATITVSVDGMS
                     KTVTAELRATMMDVANSTLSANEPSGDVVADGQQAYTLTLTAVDSEGNPVTGEASRLR
                     FVPQDTNGVTVGAISEIKPGVYSATVSSTRAGNVVVRAFSEQYQLGTLQQTLKFVAGP
                     LDAAHSSITLNPDKPVVGGTVTAIWTAKDAYDNPVTSLTPEAPSLAGAAAVGSTASGW
                     TNNGDGTWTAQITLGSTAGELEVMPKLNGQDAAANAAKVTVVADALSSNQSKVSVAED
                     HVKAGESTTVTLIAKDAHGNTISGLSLSASLTGTASEGATVSSWTEKGDCSYVATLTT
                     GGKTGELRVMPLFNGQPAATEAAQLTVIAGEMSSANSTLVADNKAPTVKMTTELTFTV
                     KDAYGNPVTGLKPDAPVFSGAASTGSERPSAGNWTEKGNGVYVATLTLGSAAGQLSVM
                     PRVNGQNAVAQPLVLNVAGDASKAEIRDMTVKVNNQLANGQSANQITLTVVDSYGNPL
                     QGQEVTLTLPQGVTSKTGNTVTTNAAGKVDIELMSTVAGEHSITASVNNAQKTVTVKF
                     KADFSTGQATLEVDGSTPKVANDNDAFTLTATVKDQYGNLLPGAVVVFNLPRGVKPLA
                     DGNIMVNADKEGKAELKVVSVTAGTYEITASAGNDQPSNAQSVTFVADKTTATISSIE
                     VIGNRAVADGKTKQTYKVTVTDANNNLLKDSDVTLTASSENLVLDPKGTAKTNEQGQA
                     VFTGSTTIAATYTLTAKVEQANGQVSTKTAESKFVADDKNAVLAASPERVDSLVADGK
                     TTATMTVTLMAGVNPVGGSMWVDIEAPEGVTEKDYQFLPSKADHFSGGKITRTFSTSK
                     PGVYTFTFNALTYGGYEMTPVKVTINAVAAETENGEEEMP"
     gene            21026..21127
                     /locus_tag="RN951_002925"
     CDS             21026..21127
                     /locus_tag="RN951_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527897.1"
                     /translation="MKENKVQQISHKLINIVVFVAIVEYAYLFLHFY"
     gene            21491..21754
                     /locus_tag="RN951_002926"
     CDS             21491..21754
                     /locus_tag="RN951_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HDX2527898.1"
                     /translation="MKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYPY
                     VTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRFVSTKKGA"
     gene            21754..21894
                     /gene="ykgO"
                     /locus_tag="RN951_002927"
     CDS             21754..21894
                     /gene="ykgO"
                     /locus_tag="RN951_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L36"
                     /protein_id="HDX2527899.1"
                     /translation="MKVLNSLRTAKERHPDCQIVKRKGRLYVICKSNPRFKAVQGRKK
                     KR"
     gene            complement(21929..22156)
                     /locus_tag="RN951_002928"
     CDS             complement(21929..22156)
                     /locus_tag="RN951_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527900.1"
                     /translation="MQAAPQREETEWRVQSKRGLMPAYRGEAGQQVNIKIMEYSERNV
                     RQLASNEQEEYIPRKINVGVINTPTLIRSDY"
     gene            22980..23522
                     /gene="ecpR"
                     /locus_tag="RN951_002929"
                     /gene_synonym="matA"
     CDS             22980..23522
                     /gene="ecpR"
                     /locus_tag="RN951_002929"
                     /gene_synonym="matA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECP biosynthesis operon DNA-binding
                     transcriptional regulator EcpR"
                     /protein_id="HDX2527901.1"
                     /translation="MECQNRSDKYIWSPHDAYFYKGLSELIVDIDRLIYLSLEKIRKD
                     FVFINLSTDSLSEFINRDNEWLSAVKGKQVVLIAARKSEALANYWYYNSNIRGVVYAG
                     LSRDIRKELVYVINGRFLRKDIKKDKITDREMEIIRMTAQGMQPKSIARIENCSVKTV
                     YTHRRNAEAKLYSKIYKLVQ"
     gene            23597..24184
                     /gene="ecpA"
                     /locus_tag="RN951_002930"
                     /gene_synonym="matB"
     CDS             23597..24184
                     /gene="ecpA"
                     /locus_tag="RN951_002930"
                     /gene_synonym="matB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="common pilus major fimbrillin subunit EcpA"
                     /protein_id="HDX2527902.1"
                     /translation="MKKKVLAIALVTVFTGMGVAQAADVTAQAVATWSATAKKDTTSK
                     LVVTPLGSLAFQYAEGIKGFNSQKGLFDVAIEGDSTATAFKLTSRLITNTLTQLDTSG
                     STLNVGVDYNGAAVEKTGDTVMIDTANGVLGGNLSPLANGYNASNRTTAQDGFTFSII
                     SGTTNGTTAVTDYSTLPEGIWSGDVSVQFDATWTS"
     gene            24242..24910
                     /gene="ecpB"
                     /locus_tag="RN951_002931"
                     /gene_synonym="yagY"
     CDS             24242..24910
                     /gene="ecpB"
                     /locus_tag="RN951_002931"
                     /gene_synonym="yagY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone EcpB"
                     /protein_id="HDX2527903.1"
                     /translation="MKKHLLPLALLFSGISPAQALDVGDISSFMNSDSSTLSKTIKNS
                     TDSGRLINIRLERLSSPLDDGQVISMDKPDELLLTPASLLLPAQASEVIRFFYKGPAD
                     EKERYYRIVWFDQALSDAQRDNANRSAVATASARIGTILVVAPRQANYHFQYANGSLT
                     NTGNATLRILAYGPCLKAANGKECKENYYLMPGKSRRFTRVDTADNKGRVALWQGDKF
                     IPVK"
     gene            24936..>26380
                     /gene="ecpC"
                     /locus_tag="RN951_002932"
                     /gene_synonym="yagX"
     CDS             24936..>26380
                     /gene="ecpC"
                     /locus_tag="RN951_002932"
                     /gene_synonym="yagX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher EcpC"
                     /protein_id="HDX2527904.1"
                     /translation="MPLRRFSPGLKAQFAFGMVFLFVQPDASAADISAQQIGGVIIPQ
                     AFSQALQDGMSVPLYIHLAGSQGRQDDQRIGSAFIWLDDGQLRIRKIQLEESEDNASV
                     SEQTRQQLMALANAPFNEALTIPLTDNAQLDLSLRQLLLQLVVKREALGTVLRSRSED
                     IGQSSVNTLSSNLSYNLGVYNNQLRNGGSNTSSYLSLNNVTALREHHVVLDGSLYGIG
                     SGQQDSELYKAMYERDFAGHRFAGGMLDTWNLQSLGPMTAISAGKIYGLSWGNQASST
                     IFDSSQSATPVIAFLPAAGEVHLTRDGRLLSVQNFTMGNHEVDTRGLPYGIYDVEVEV
                     IVNGRVISKRTQRVNKLFSRGRGVGAPLAWQVWGGSFHMDRWSENGKKTRPAKESWLA
                     GASTSGSLSTLSWAATGYGYDNQAVGETRLTLPLGGAINVNLQNMLASDSSWSSIGSI
                     SATLPGGFSSLWVNQEKTRIGNQLRRSDADNR"
BASE COUNT         6901 a         6650 c         6188 g         6641 t
ORIGIN      
        1 taattaaacc ttaaataaca aatggttgcg ttaatttcag ttgatttacg atacacattt
       61 ctcatgaata atgcgtcatt tcaaatgatc agcaatattt acattaaata agactaaact
      121 tattgaacat tcgcaacagc ccaaatgtag gttttgggct gcaatagttc ttttcttttt
      181 tattatctgt tgtctggtaa tcatcaatag atactaaggg cttaaccgta tagatataac
      241 gtatcaagag gtaggagaaa cagcgccata tgcagacatg gcgcggtttt atgcaataac
      301 aatcacgcgt ccgggaacat cacgctatgg cccggcgctt cacgatggag atgaataaag
      361 ttaaggtgcc gctcgtactg gtcaagaata tcggtgatca cctgctcttt gctgtagtcc
      421 atcaggtcgt tgccctggct gccttctaac aggaaggttt ccagccggta gtaggtcgat
      481 ttaccgctgc gtgcgcggta ggtaaagccc ggcaccgaat attgctgcgg ccaaatctga
      541 tagacaaagt tttgctcttc gcccatatgc accaacaaat ccagatgacc caactgctgt
      601 ccctcttccg gtggcaggct ttttagctcc acgtacgcgc cgcgcaaccg caactcctgc
      661 gccacttctt ccattgccgg gtaacagacc gtctccatca tctgtttagt gtaacgcgtg
      721 cccggataat tcatcaggcg cgagagacgt tttttccagc tcaggcgatc ctgaagcccc
      781 agcggtcgcg gtgcggtatc gcggttggca ctttcacggc ggtaatcttc taccttcaga
      841 gatttataca accccgccat cacgaagaag atcacaaagc tgaacggcag ccccataatc
      901 accgtggtgt tttgcagcgc ggatatcccg ttagtcatca gcatgccgag cgtcagcagg
      961 ccaatcgcca ccgaccagaa gacgcgcagc cagccggggg cgtcgctgtt gatatcttta
     1021 agctgcgagg tgaaattccc cagcaccagc gccccggagt ccgccgaggt cacataaaac
     1081 agcaggccag taatggtggc gacggaggcg ctaaaggtaa acgccggata ctgcgccagc
     1141 aggctgtaga agccgcgctc cggatggacc atcgcttcct cggcaaatgc cgcgccgccg
     1201 tggatgattt catacagcgc gctattgccg aacaccgaga gccataacag cgtgaaggta
     1261 aacggaataa tcaacgtgcc cagcacgaac tggcgaatgg tacgcccacg cgagatacgc
     1321 gccaggaaca agccgacaaa cggcgaccat gccacccacc atgcccagaa gaagagcgtc
     1381 cagttattca tccactcaac cggacggtcg aaggcaaaac tgttgagcgt catgcccata
     1441 aagcgattca catagtcgcc aacattcagc accagtgcat taagcaggaa cgaagtgtcg
     1501 cccataaaca atacgaacag gatcaatccc agcgccagcg cgacattaag ctccgataac
     1561 acgcgaatgc ccttatcgac accggaggtg acagagatcg tggcgattat caccgacaag
     1621 gcgatcagtg ccgctttcgc cgccatcgaa tcgggaatat caaacagtac gctcaagcca
     1681 tagttaagct gcaccacacc gataccgagc gtagtggcaa taccgaagat agtgccgatc
     1741 accgctgcaa tatccactga gtgacctatc ggcccgttaa tccgtttacc gaagatcggg
     1801 tacagcgccg agcggatggt gagcggcaaa ttataacgat agctaaagta tccgagcgcc
     1861 atgcccatca gcgcatacat cgaccagccg gttaagccgt agtgaaacag cgtccagacc
     1921 atcgcctgac gcgcggcctc aatcgtctgt cccgcgcctt ccggcggctg catatactgc
     1981 gttaccggtt cggctacgga gaagaacatc aggtcgatac cgatcccggc agcaaacagc
     2041 atcgccgccc aactcagcag gctgaattcc ggtttggatt gttctggccc gagcttcacc
     2101 gaaccaaaac gcgaacaagc gatacagacc acaaagacaa tatagagcgt tgccgccagc
     2161 agatagtacc aaccgaaggt tttagaaacc cagtccagcg tgcggccaat ccacagggcc
     2221 gagaagtcgc gaaacaggat cgttgtcagg gaaaacaaca aaatcagtcc ggcggaggtg
     2281 taaaacacca ccggattgat tttgtccttt tccctgctgt gtgaaaggtc tgtcatccag
     2341 tatccccact gttattgtta ctatttaaaa tcaaattcgt aacaattaag acacatttta
     2401 tattgaacgt ccaatcaata accgctttaa tagataaaca ccgctgatga atggagtggc
     2461 gaaaatgccc aaattgggga tgcagtcgat ccggcgcaga caactgatcg acgccacact
     2521 ggaagcaata aatgaagtgg gcatgcacga tgcaacgatc gcgcagatcg cacgccgtgc
     2581 aggcgtttct acggggatca tcagccacta tttcagggac aaaaatggtc tgctggaagc
     2641 aaccatgcgc gatatcacca gtcagctgcg tgacgcggtt ttgaatcgat tacatgcact
     2701 tccgcagggc agtgcagagc agcgattaca ggcgattgtt ggcggaaact tcgatgaaac
     2761 gcaggtgagc agtgcggcga tgaaagcctg gctggcgttc tgggccagca gtatgcatca
     2821 gccgatgctc tatcgtttac agcaggtcag cagccgccgc ttgctgtcga atctggtgag
     2881 cgagtttcgt cgcgaattgc cgcgcgaaca ggcacaggaa gcgggctacg gcctggccgc
     2941 gctgattgat ggattatggc tgcgcgcggc tctgagcggc aaaccgctgg ataaaacccg
     3001 cgctaattcc ctgacccgcc actttatcac tcagcatcta cccaccgatt aaccgaggag
     3061 acgtgatgtc ccgaatggca gaacagcagc tttatataca tggtggttat acctccgcca
     3121 ccagcggtcg caccttcgag accattaacc cggccaacgg taacgtgctg gcgaccgtgc
     3181 aggccgccgg gcgcgaggat gtcgatcgcg ccgtgaaaag cgcccagcag gggcaaaaaa
     3241 tctgggcgtc gatgaccgcc atggagcgct cgcgtattct gcgtcgggcc gttgatattc
     3301 tgcgtgaacg caatgacgaa ctcgcaaaac tggaaaccct cgacaccgga aaagcatatt
     3361 cggaaacctc aaccgtcgat atcgttaccg gtgcggacgt gctggagtac tacgccgggc
     3421 tgatcccggc gctggaaggc agccagatcc cgttgcgtga aacgtccttt gtgtataccc
     3481 gccgcgaacc gctgggcgta gtggcaggga ttggcgcatg gaactacccg atccagattg
     3541 ccctgtggaa atccgccccg gcgctggcgg caggcaacgc aatgattttc aaaccgagcg
     3601 aagttacccc gcttaccgcg ttaaagctgg ctgaaattta cagcgaagcg ggcctgccgg
     3661 acggcgtatt taacgtgttg ccgggcgtgg gcgcggagac cgggcaatat ctgaccgagc
     3721 atccgggcat tgccaaagtg tcatttaccg gcggtgtcgc cagcggcaaa aaagtgatgg
     3781 ctaactcggc ggcctcttcc ctgaaagaag tgaccatgga actgggcggt aaatcaccgc
     3841 tgatcgtttt cgatgatgcg gatctcgatc tcgccgccga tatcgccatg atggcaaact
     3901 tcttcagctc cggtcaggtg tgtaccaatg gcacccgcgt cttcgttccg gcgaaatgca
     3961 aagccgcatt tgagcagaaa attctggcgc gcgttgagcg cattcgcgcg ggcgacgttt
     4021 tcgatccgca aactaacttc ggcccgctgg tcagcttccc gcatcgcgat aacgtgctgc
     4081 gctatatcgc caaaggcaaa gaggaaggcg cgcgcgtact gtgcggcggc gatgtactga
     4141 aaggcgatgg cttcgataac ggcgcatggg ttgcaccgac agtgttcacc gattgcagcg
     4201 acgatatgac catcgtgcgt gaagagatct tcgggccagt gatgtccatt ctgacctacg
     4261 agtcggaaga cgaagtcatt cgccgcgcta acgataccga ctacggccta gcggcgggca
     4321 tcgtgacagc ggacctgaac cgcgcgcatc gcgtcattca tcagctggaa gcgggtattt
     4381 gctggatcaa cacctggggc gaatccccgg cagagatgcc cgttggcggc tacaaacact
     4441 ccggcattgg tcgcgagaac ggcgtgatga cgctccagag ttacacccag gtgaagtcca
     4501 tccaggttga gatggctaaa ttccagtcca tattctaacc aggaggttta tttgcaattt
     4561 gactacatca ttattggtgc cggctcagcc ggcaacgttc tcgctacccg tctgactgaa
     4621 gatccgaata cctccgtgct gctgcttgaa gcgggcggcc cggactatcg ctttgacttc
     4681 cgcacccaga tgcccgctgc cctggcattc ccgctacagg gtaaacgcta caactgggcc
     4741 tatgaaacgg aacctgaacc gtttatgaat aaccgccgca tggagtgcgg acgcggtaaa
     4801 ggtctgggtg gatcgtcgct gatcaacggc atgtgctaca tccgtggcaa tgcgctggat
     4861 ctcgataact gggcgcaaga acccggtctg gagaactgga gctacctcga ctgcctgccc
     4921 tactaccgca aggccgagac tcgcgatatg ggtgaaaacg actatcacgg cggtgatggc
     4981 ccggtgagcg tcactacctc caaacccggc gtcaatccgc tgtttgaagc gatgattgaa
     5041 gcgggcgtgc aggcgggcta cccgcgcacg gacgatctca acggttatca gcaggaaggt
     5101 tttggtccga tggatcgcac cgtcacgccg cagggccgtc gcgccagcac cgcgcgtggc
     5161 tatctcgatc aggccaaatc gcgtcctaac ctgaccattc gtactcacgc tatgaccgat
     5221 cacatcattt ttgacggcaa acgcgcggtg ggcgtcgaat ggctggaagg cgacagcacc
     5281 atcccaaccc gcgcaacggc caacaaagaa gtgctgttat gtgcaggcgc gattgcctca
     5341 ccgcagatcc tgcaacgctc cggcgtcggc aacgctgaac tgctggcgga gtttgatatt
     5401 ccgctggtgc atgaattacc cggcgtcggc gaaaatcttc aggatcatct ggagatgtat
     5461 ctgcaatatg agtgcaaaga accggtttcc ctctaccctg ccctgcagtg gtggaaccag
     5521 ccgaaaatcg gtgcggagtg gctgtttggc ggcactggcg ttggtgccag caaccacttt
     5581 gaagcaggtg gatttattcg cagccgtgag gaatttgcgt ggccgaatat tcagtaccat
     5641 ttcctgccag tagcgattaa ctataacggc tcgaatgcag tgaaagagca cggtttccag
     5701 tgccacgtcg gctcaatgcg ctcgccaagc cgtgggcatg tgcggattaa atcccgcgac
     5761 ccgcaccagc atccggcgat tctgtttaac tacatgtcgc acgagcagga ctggcaggag
     5821 ttccgcgacg caattcgcat cacccgcgag atcatgcatc aacccgcgct ggatcagtat
     5881 cgtggccgcg aaatcagccc cggtgtcgaa tgccagacgg atgaacagct cgatgagttc
     5941 gtgcgtaacc acgccgaaac cgccttccat ccgtgcggta cctgcaaaat gggttacgac
     6001 gagatgtccg tggttgacgg cgaaggccgc gtacacgggt tagaaggcct gcgtgtggtg
     6061 gatgcgtcga ttatgccgca gattatcacc gggaatttga acgccacgac aattatgatt
     6121 ggcgagaaaa tagcggatat gattcgtgga caggaagcgc tgccgaggag cacggcggga
     6181 tattttgtgg caaatgggat gccggtgaga gcgaaaaaat gagtcgtgat gtgaactaac
     6241 gcaggaaccg atcagattga gagttaccgt tccagagagg gggaccgaat ccttatataa
     6301 acactgaggt aactctcatg cttcatatcc agtattcatg atgcgggctt tttgctgata
     6361 tttaacccga acattcctga tacagactat taatacaacc ttatctgcga cagattttat
     6421 tctctggata tattatgcgt gaacaaatca aacaggatat cgatctgatt gagattttat
     6481 tttatctgaa gaaaaagatt cgtgttatcc tttttattat ggctatatgt atggctatgg
     6541 tgctgttgtt tctgtatatc aataaagaca atataaaagt gatttacagc ctaaaaataa
     6601 accagacaac gccaggtata cttgttagct gtgatagcaa taataatttt gcctgtcaga
     6661 ctacaatgac tgaagatgtt attcagcgaa ttactacatt ttttcacacc agcccagatg
     6721 tcaagaacag agaaataagg ctggaatggt caggagataa gagagcttta ccaactgctg
     6781 aagaggaaat atctcgcgtg caggcctcta ttatcaaatg gtatgcgtca gaatatcata
     6841 atggcaggca agttctcgat gagatacaaa cgccttcagc aattaacagt gagctttata
     6901 caaaaatgat atacctgacc aggaactggt cattgtatcc gaacggtgat ggctgtgtaa
     6961 ctataagctc accagaaata aaaaataaat accctgctgc catttgcctg gctctgggat
     7021 tttttctaag cattgtaatt tctgtaatgt tttgccttgt caaaaaaatg gtagatgaat
     7081 accaacaaaa ctctgggcag taataaacaa cattctgata gagagtgcct gtataaagct
     7141 gaagtgacaa tgaccgggaa gggaacccgt tttcaggaat ggatgcctgt ctttttcact
     7201 gtaaatatcc tggcattggt aataccagga tatttacaga agagcagcat aaccatgacg
     7261 gaacggggtt aagtcaggtt gtcctaaacg ctattttcaa cctcgtatgc cttcttcagg
     7321 tttatgtcca gacttcatat ctctctcaac aatcctcaat aatcagatac accgctttca
     7381 ccgggccatg aactccgacg actttgataa gctcaatatc cgccgttgaa ctggggccgc
     7441 taatgatgtt aatgcaggaa ggcattcgtt caccggcctg cgctttctga tgcaattttt
     7501 ctgcgagttg cgctacacgc ggcaggatag tgcttttacg caggataaaa agagaatatt
     7561 ccgggagcag gctcaatgaa cgcccgcgct cggcggcgga aaaaagaacc acgcctcccg
     7621 attcggttaa accatattca gcatacacaa cacccacttt agcctgctct gcctgcgaga
     7681 tattctcggc acctttcgcc ggatcccaaa caacggcatt gcattcctgc tgcaaacgtt
     7741 cgctaatccc caattcctcc agcctcgtgt caccgctaat cacgaccgac tgatctccca
     7801 gctctttaca cagacgtatt gcagcttctg ccgccttcgc ctcgctggtc agctcacagc
     7861 gcgtcaacat aacatcgctg gcaaactgaa taaacgcgtc acagcgctgc tgttggttaa
     7921 gttgggtaag ccgctcgtta gcatagttgt taagcggcgc atcttctgct tgcggttcaa
     7981 gtcgcagcgg gcgacccagt gcctgagcaa cgttattcaa aaattcgcct cgattatcca
     8041 ttctttttct cctgcgcctg atgtttctta aaccaactac ggaaactctc tccgtcagct
     8101 tcaggaagat cgcgtgcttc catccagtcg ctaatcgcgc caaatttgag tggtgttttg
     8161 ccgccattga taaaccagct tgccgcatga gcaccggcca tcatcccgac tttccacaat
     8221 cctggatgac tattggcata agcgaacatt tttatcgccc gttgctctgc ttttgcggtg
     8281 atcccttttt cagccatcac ccgacgatga cgcaaaatca gttttgacag cggaatacgc
     8341 accggacaca cgttgtcaca agctgtgcat aaagagcagg cgtagggtaa atctttaaaa
     8401 tctttatagc cgccaagtag cggagaaatc accgcaccaa ttggccctgg ataaatagag
     8461 ccatatccat gaccgccaat atggcgatat gccggacaag tattcataca agccccgcag
     8521 cgaatacagc gcagcacatc ccgaaattca gaggccagca cctcagaacg cccgttatcg
     8581 acaataacca gatgaaactc ttcaggacca tcaacgtgcc cagcttcgcg cggtcctgtc
     8641 agccaggtgt tgtatcccgt caaacgtgca ccaacggcac tgcgcgccag catggtgatc
     8701 aatacatcta cctcggcaaa cgtgggggca atacgctcca ttcccatcac tgcaatatgc
     8761 gttttaggca gcgtggtaca cattcgcgca ttaccttcat tggtcaccag gcataccgaa
     8821 ccggtctctg ccaccgcgaa attacagccg gtaataccta tttcagcact gaggaaatct
     8881 tcgcggattt tttgccggat gaataaggtc atcgcttcag gcgtttccgg cccctcatag
     8941 cccagacgtt cgtgtagcac tcgacggatc tgatggcgat ctttatgaat tgccgggacc
     9001 acaacatgag atggcggatc ttgatccagc tggagaatat attcacccag atcggtttca
     9061 atcacctgaa tgccagcatc ctgcaacaca tgattgacac caatctcttc ggtcaccatc
     9121 gatttagatt tcaccacctt ccgggcattt ttgcgttggg caacctgtaa aatgtagcgg
     9181 gtagcgtctt ctttggttct tgcaaaatag acgtgaccgc cgttttgcgt cactttttct
     9241 gagagctggt acagataagc gtcgagatta ctcagaacat gatcacgtat ctgggcggcc
     9301 cgatcgcgcc actcctccca gtgccccaat tcatcgacca ttttttgccg atttgcccca
     9361 atacgctgct gcgcgtttgc caccgctttg cgcatgatcg gatcttcaat ttgctgacgg
     9421 atgcgtgtct taaaatctgt attactggtt ttgatcgaca tctttatatc ctcagcggct
     9481 catcaacact tcagcaatat gcatcacttt gactttctgc ccttcccgtt gtaatcgccc
     9541 actgatgttt agcaggcaac tcacgtcagc accaattaaa tactcagggc ggacttccat
     9601 caggtgcgca accttttctt tcaccatctc gccggatatt tcggccattt tgaccgagaa
     9661 cgtgccgcca aatccgcagc aggtatcctg ttcagcaaag gtcaacagct ccagtccacg
     9721 cacatttttc agcagcgtaa gtggctcgtc cttcactccc agcttacggg ccaggctaca
     9781 agatgggtga tacaccgctc tcccttgcaa actggcacct acatcgacta cccctaattt
     9841 attaacaata aaagaggtga gatcctgcat acgcgcggca acctttgcgg cacgtgatgc
     9901 ccattcaggt tcatccgcca gatacgtcgg gtaacttttt acggcatagg tgcaagagcc
     9961 agccggtgaa ataatgggat cgtcgttatc ctccagtgcg gcgatcagat ttttcatccc
    10021 tggaatcgct tctttgatat aaccgctatt gatcgcaggc tgaccgcagc atccctgttt
    10081 ctccgggaaa tttacgcgac agccgagttt ttccagtagc agcacggagt ctcgtgccat
    10141 tcttgatttc agggcgtcac caatacaggt gacaaagaaa ttgacattca caactaatac
    10201 tccattactt catgcccatt tatgcccgat gtttcccccc caccggggga tcaatcatca
    10261 ataaatatgg cgttcttttt taattggcta gcaacatacc acccctcatt tgtatgacaa
    10321 atgataatct ttcatccaaa cgtcaaatgc aataactaat tttatttctt tcggcatcgc
    10381 tcacatttta tggggaaatc gacgatcatt tttggcataa gaaatccatt taaaaatggc
    10441 tacatccctt atacctattc agagctactt attcaggggt tattgagata tacactgatg
    10501 gtgtacaaaa aaatcaccga caataatcac gtatcaagta atagtcggga ttttatttaa
    10561 ttgaagcaat ttagtttgca tttttattta aaaactgagc tagagtccat cagaaaaaat
    10621 atataaagcc caaaccaccg ttggaaatag aaatagttga aaggctcaca actcccggaa
    10681 tgcggattat ctttgccctg atttctggcg gttttattca gggtgcaagc tgtctgaccc
    10741 tttccctata ttctcccggg gtacaaccaa actcgcggac aaacgccttg tgaaaagatg
    10801 attcactggc atagcctact gactcagcga tcaccacaac agggagcgtt tcccgggaaa
    10861 acatctgggc cgctatttgt agacgcaact ttgttaatac agccagcggc gtggttccgg
    10921 aaacatcacg gaaaagctgg gcaaaacttg cccgggacat gtgagcgatg ctggccagcg
    10981 attcgacggt ccaggcgtgt cctggcattt ccagcatttg ctgtattacc gcaccaagac
    11041 gtggatgcag aagcaaactg agaatgtttt tctcagtatt aacctgtgca atccactcac
    11101 gcaccgcgag ggtaaagaat gtagcgcaga tctggctaca cagtgcatcc actcccggca
    11161 ttgccgatct ggattcctgt tgtaaaaacg ggatcgcctc cctcagccag ttatattcca
    11221 cgctgtggtt aaccggtgct aaaaacagcg tttccggcaa agacgttaaa aaataacgcg
    11281 ccgaatgttg caaccgaaga gtgccgcaga caatacaggt cgattcatta tcgacatgac
    11341 tcaggcgatg agctgaattt tgtggtagca ggaccacatt tcccgggcgt aatgtaaaaa
    11401 tctcccccgt cggcatttcc agcttcgccg ctccttgcgt taacgcatgc caacgaataa
    11461 ccgataattc cccggcacca tgtggaagct gccagtcact tcctaacacg caattcttat
    11521 cgatcgttcc ttgtggagcg ttaagcatca acaaacggct aagggcatcc atatcagact
    11581 cctgagtggt ttttgattac aaacaccaac aatcttagta aataactaat ctaataccat
    11641 caaatagtta atcatgattt ttgttttgtg attctgatta agaaaaagaa aatatcagac
    11701 gataagacaa aatatcaagc gttgtgaaga aatgttattt gctcttttgc gtctatagtc
    11761 atgatgtcaa atgaacgcgt ttcgacagga aatcatcatg aataaatatc aggcagtgat
    11821 tattggtttt ggcaaggctg gaaaaacatt agccgtcacg ctggcaaaag caggttggcg
    11881 agtggctctc atcgaacaat caaatgcaat gtatggcggg acctgtatta atatcggctg
    11941 catcccaacc aaaacattgg ttcatgacgc acagcagcac acagattttg tccgtgccat
    12001 acagcgtaaa aatgaagtgg ttaatttttt acgtaataag aattttcata atcttgcgga
    12061 tatgcccaat atcgacgtga tcgacggcca ggcggagttt atcaataatc atagcctgcg
    12121 tgttcatcgg cctgagggaa atctggaaat tcatggcgag aaaattttta ttaataccgg
    12181 tgcacaaacc gtggttccgc caattcctgg aattaccacc acgccaggag tatatgacag
    12241 caccggatta cttaatctaa aagaattgcc tgggcattta ggtattttgg gcggcggata
    12301 tattggcgtt gagttcgcct ctatgttcgc taattttggc agcaaggtaa ccattttaga
    12361 agcagcttcg ctgtttttgc ctcgggaaga tcgggatatt gctgataata tcgcgacgat
    12421 tttacgcgat cagggcgtcg atattatcct caatgcccat gtggagcgaa tcagtcacca
    12481 tgaaaatcaa gtgcaagtgc atagcgagca cgcccaactg gcggtggatg cactgttaat
    12541 agcttccggt cgtcaaccgg ctaccgcttc gttacatcca gaaaatgccg gtatcgcagt
    12601 aaacgagcgc ggggcaattg tcgttgacaa gcgattacat accaccgcag acaatatttg
    12661 ggcgatggga gatgttaccg gcgggctgca atttacttac atatcactgg atgattaccg
    12721 cattgtacgt gatgagttac tgggtgaagg caaacgtagt actgatgatc ggaaaaatgt
    12781 gccttattcc gtatttatga caccgcccct gtccagggtt ggtatgacag aagaacaagc
    12841 cagagagagt ggtgctgata ttcaggtggt gacattgcct gtagctgcaa ttccgcgtgc
    12901 cagagtgatg aatgatactc gtggggtatt aaaagcgatt gttgataata aaacccaacg
    12961 tatgttaggg gcatcactgc tgtgtgttga ctcccacgag atgatcaata tagtgaaaat
    13021 ggtgatggat gccgggctgc cttatagcat attacgcgat cagatattta ctcatccgtc
    13081 gatgagcgaa tcactcaatg atctattttc attagtcaaa taaactcaaa atcagacgcc
    13141 agaacaaata ttctggcgtc tcagagaaaa gaatcttatt aattctctgt tactctataa
    13201 cttcttaatc acttcattga tggtatttta tatgtttaaa aaatctgttt tatttgcaac
    13261 actattatct ggcgttatgg cattttccac caatgcagat gataaaataa ttctgaaaca
    13321 tatcagcgtc tcgtcagtat cagcatcacc gacagttctg gaggatacca ttgctgatat
    13381 agccagaaaa tataatgctt catcctggaa agtcacatcg atgcgaattg ataataattc
    13441 aaccgcaaca gcagtattgt ataaataagg atgttcacaa tggaaaaata cctgcacctg
    13501 ttaagtcggg gagataaaat tggcctgaca ttgattcgtc tgagtattgc aattgttttt
    13561 atgtggattg ggttattaaa gtttgtccct tacgaggcag acagcattac accattcgtc
    13621 gcaaacagtc cactaatgtc gttcttttat gaacacccgg aagactataa acagtatctg
    13681 actcacgaag gcgaatacaa accagaagca agggcatggc aaacggccaa taatacctat
    13741 ggtttttcca acggtcttgg cgtcgtggag gtgattattg ctctgctggt tttggctaat
    13801 cctgtcaatc gctggttagg tttattggga ggactgatgg catttaccac gccgctggta
    13861 acactctcat ttttaatcac caccccggag gcatgggtac ccgcattggg tgacgctcat
    13921 catggtttcc cttatttatc cggtgctggt cgcctggtat tgaaagatac tctgatgctg
    13981 gcaggtgcag tcatgataat ggcagattcg gcgcgggaaa ttcttaaaca acgcagtaat
    14041 gaatccagtt caacgttaaa aactgaatat tgataatccg aacactgtct gttgttcact
    14101 ttttcaggcg tcaggccccc tttctgatga tgaagcctga cgccatatta ccggagatat
    14161 gacagagtga agatcaatat cactccctgt taaaaggttt ttgtcgtctt aggtaaaata
    14221 catgattaat atcaatcatg tatttttaca gcaagacaac cacgaacaaa ttcaggatta
    14281 aaatgtttta ccgactcccc aacataaccc aaatcaagcg aactaatttg tgccatttct
    14341 ttatctgtca gtgagaaatc gatttttgat gggcatctgc aatactctga agcagactat
    14401 acggaaaatt ccactgtcag tccctccatt aggcatgaac aatgagtcta cgttaaaacg
    14461 taacctcaaa gtagtatgtg gattttgata tcacttatgc aaaaaattca ttaataatgt
    14521 aggactgaaa cctctctatt ttcggggaca acgaagcaga cgctaccagt gcttttgcct
    14581 tcgcccttgc tatttttgat acacttaggg cccagggtat aacgaaaatg tgcgatatga
    14641 caaagaatta acggagaatg agatgatcag gcagaagatt ctacagcagc tcctggagtg
    14701 gattgagtgc aatcttgagc accctatttc aatcgaagat atcgcacaga aatctggcta
    14761 cagcagacgc aacatccagc ttctgttccg aaatttcatg catgtgcctt tgggagaata
    14821 cattcgcaaa cgaaggcttt gtcgtgccgc cattcttgtc cggctcaccg cgaaatctat
    14881 gcttgatatt gcactctctt tgcattttga ttcacagcag tcattcagcc gcgaatttaa
    14941 aaagttattc ggctgctctc cccgtgaata ccgccaccgt gattattggg atctcgcaaa
    15001 tatcttccct tcttttttaa tacgtcaaca gcaaaagacg gagtgtagat taatcaactt
    15061 tcctgagaca cctatttttg gcaactcatt taaatatgac attgaagtgt cgaataaatc
    15121 accggatgaa gaagtcaaac tacgacgtca tcatttagcc agatgtatga agaattttaa
    15181 gacggatatc tatttcgttt ccacgtttga accgtcaaca aaatcggtcg atttgctcac
    15241 ggttgaaact tttgctggta cggtatgtga atatgctgac atgccaaaag agtggacaac
    15301 gacccgagga ctttatgcct ctttccgtta tgaaggaaac tgggaaaatt atcctgactg
    15361 ggtgcgtaac atctatctga tagagttacc tgccaggggg ttagccagag tgaacggcag
    15421 cgatattgag cgcttttatt acaatgaaga tttcgtagaa aaggatggca atgatgttgt
    15481 ttgcgaaatt tttattcccg ttcgtccggt ttagttggtc actatctctt attgagtttt
    15541 atccttgcct gatactattt aatcagtatc aggcaaggta ttcagtgaat aatggcgttg
    15601 aatatttcaa caccattatt ctttattaga tcgtaacttt catactattc aaattatggc
    15661 atctcctcct cgccattttc agtctctgca gcaacggcgt taattgtcac cttcacaggc
    15721 gtcatttcgt acccgccata cgtcagtgcg ttgaatgtga acgtatagac acctggcttg
    15781 ctggtactaa atgtacgcgt gattttccca cctgagaaat ggtcagcctt cgacggcagg
    15841 aattgataat ccttctccgt cactccttcc ggagcctcaa tgtcgaccca catacttcct
    15901 cctacgggat tgactcccgc catcagggta accgtcattg ttgcagtagt cttcccgtcc
    15961 gccaccagag aatctacacg ttctggagat gcggcgagca ccgcgttttt atcatccgcg
    16021 acgaatttag attcagcagt tttcgtcgat acctgaccgt tggcctgttc cactttcgcc
    16081 gtgagtgtat atgtcgctgc gatagtggta gagccggtga aaacagcctg tccttgctca
    16141 ttagttttcg ccgtcccttt aggatccaga actaaatttt ccgagctggc agtcagcgtc
    16201 acgtcgctat ccttcaacag gttgttattg gcatcagtca ccgtaacttt atacgtctgt
    16261 ttggttttgc catccgccac tgcacggttg ccaatcacct caatactgga gatggtcgcc
    16321 gtagtcttat cggccacaaa cgttacagac tgcgcattcg aaggctggtc atttcctgcc
    16381 gacgccgtga tctcatacgt tccggcagtc acggagacca ctttcagttc cgctttaccc
    16441 tccttgtcgg cgttcaccat gatattaccg tctgcaagcg gtttgacgcc ccgaggcaga
    16501 ttaaagacga ccacagcgcc aggcagaagg ttgccgtatt gatccttaac cgttgccgtc
    16561 agcgtaaagg catcattgtc gtttgccact tttggcgtgc tgccatcaac ctccagggtc
    16621 gcctgaccgg tactgaaatc cgccttgaat ttcaccgtaa ccgtcttctg agcattattc
    16681 actgaggccg tgatgctgtg ttcccccgca accgttgaca taagctcaat gtccactttc
    16741 cctgccgcat tggttgttac tgtattcccc gtcttgctgg tcacaccctg cggtaaagtc
    16801 agcgtaactt cttgcccctg caacgggtta ccatagctgt ccacgacggt cagggttatc
    16861 tggttagcag actgtccatt agccagttgg ttattaacct tcactgtcat atcacgaatc
    16921 tcagccttag atgcgtcacc tgcaacgttc agcaccagtg gctgagcaac ggcattttgg
    16981 ccgttcactc gcggcatcac agacaactga cccgcggcag atcccagcgt taaggtcgcc
    17041 acgtagaccc cattaccttt ctctgtccag tttcctgctg aaggacgctc actccccgtg
    17101 ctggcggcac cgctaaacac tggtgcatct ggcttcagcc cggtgaccgg gttcccgtac
    17161 gcatccttca cggtgaaggt gagttccgtc gtcattttga cggtcggagc cttattgtcc
    17221 gcaacaagcg tagagttcgc tgatgacatc tctccggcga tgaccgtcaa ctgcgcggct
    17281 tcggtggctg ctggctggcc gttgaagagc ggcatgacac gaagctcgcc cgtctttccg
    17341 cctgtagtta acgtagcaac ataggaacag tcaccttttt cggtccaact ggaaacggtc
    17401 gccccttcag aggcggtccc cgtcaaactt gccgacaacg aaagaccact gatagtgttg
    17461 ccatgtgcat cttttgcaat aagcgtcacg gttgtgcttt cgccggcttt tacgtgatct
    17521 tctgcgacag agactttcga ctggtttgaa gataacgcat cagccaccac ggttactttt
    17581 gccgcatttg ctgccgcatc ctgtccattt agcttcggca taacttctaa ttcacccgcc
    17641 gtagagccga gagtaatctg cgcagtccac gtcccatcac cattatttgt ccagccagat
    17701 gccgtagaac ctacagcagc ggcacccgct aatgacggcg cttccggcgt gaggctggtc
    17761 acagggttgt cataggcatc ttttgccgtc cagattgccg taactgtacc gccaaccacc
    17821 ggtttatcag gattcagggt gatggacgaa tgtgctgcat caagcggacc ggcaacaaac
    17881 ttcagcgttt gttgtaatgt gcccagctga tactgctcgc tgaaagcacg cacaacaacg
    17941 tttccggcac gggtcgaaga aaccgtggcg ctgtaaacgc ctggttttat ttccgaaatg
    18001 gcaccaacgg ttacaccatt agtgtcttgc ggaacaaatc gcaagcggct ggcttctccc
    18061 gtcaccggat taccctcgga gtccaccgca gtcaacgtca acgtataggc ttgctgacca
    18121 tcagcaacca catcacctga cggctcgtta gcgctcaggg tggagtttgc cacatccatc
    18181 atcgtggccc gcagttctgc agtgacggtt ttgctcatgc catcaacgct aacagtaatc
    18241 gttgcctcac ctgactgcgt tccggtagta aagacagact gatacacccc tgcttcagtt
    18301 tcggtgaact cacccagtgt tggctttgcc tgtgatttag tggccttcag ggaacgagtc
    18361 acaatatttc cagccggttt gaaggctagt tcagtcttga tctgatcttt cgtgcccgtg
    18421 actggctgcc cctcggcgtc gcgcagagac agcaccagcg gtctttgctc attaccgtta
    18481 gcaagcattt gaatacggct ctgaccgtca agcgttaacg ccgtgcgatc ggcgctcata
    18541 cctgctccgg taatgaccac ctctgtctgc acgcgttttg aggcattgcc tttgttatcg
    18601 taggcaaccg cagaaatcgc ataataattg tctttgcctg gacgataagc cgggagcgtt
    18661 acttgccact gactaccctg accggtaatt ttgccaccct cagccagtaa tgacggcgct
    18721 tcccactgca catttttcag tccgtgagtt gctttgctga ccacaagccc cagggaaagt
    18781 gtctgaccac ccttaccttc aatacgttca ggcagagcaa tacggatcac ttcagatttg
    18841 cggtactcaa gaacgatgtt gttattacgc tcaaccaggt catagcggct gcctgccagt
    18901 acccgacgct cgcgaatgct gtctgtatcg agttgtttcg ccagaggttc gccaatccga
    18961 taattaactt ccaggccaaa gcgagtgtca ttctcaccac tcttgccctg cttatgcccg
    19021 gcgctcagtg tcagaagagg cactggcgta taggtcacct cggcagaaat agcatgcggg
    19081 tctttctggc gcttatcttt accaaacagc ccgacttcat cgccataata ctgttcatac
    19141 atcaggcttg cgccaagctg cggccaggcg ggtaaatagc cctcagcacg aatatcccag
    19201 ccattcgccg ggcgttcctg ataatcctca atatccggcg attttttcca gccagaagcc
    19261 cgaatataac cattggcgct cagtttcaga taatcgcgcc agtattccgc accaacacca
    19321 atgcgggtat gactacggga taaatcatga tcgataaaag tattcacccc cgccatccag
    19381 tcatttcctg aaaaatgacg ccagccaaaa ccaatatttg actgagtacg atcgtctgta
    19441 cgatgtattg ccccctgagt gaacaacata tttgtcggcg tatcataaat cggataaagc
    19501 atttccagcg aagaatcctt cagcgagaaa tctttatcga cattcagttt gacgcgcgca
    19561 gtaccatatt tcccgagcca ctcctgtatt tcctggttag ctttagctgt ggccattccg
    19621 gtaataaagt tacgtgtcgc atcgctatct ggctgactgc ttaaaaatgt cccggcattt
    19681 gcggcaaacg acgcgacatt tttctccacg ttattatcag cagttaccgt agtatttccc
    19741 atgctcaacc gtggctgaac cgcatgctgc gcacgtgccg ccattactgg ggtaaaggtg
    19801 acagcgagtg gaaaaagaac ctgaacagag atatttgccc acgccacgca gcgggccaga
    19861 actgaataac gaaatcgtgg ttgtttatga cctgttttat aatgtgacat tgagataatt
    19921 tcctgatgaa cgaattaacg aacataggca gacacaaata atggcgtctg cttgtcagaa
    19981 aaaccgggga tttcccgatt tccttttccg cagaaaagga aataccttta tgtaagaaag
    20041 tgcaccgcca cctaatatat ccagtgccta tagccactca tcaggtggtt gggcgcggga
    20101 ttatattttt atttatgggg gggaaattta gctttttgtg caagtcatta aatagatacc
    20161 taagttatat ttcttactct gcggacagtg aataattcac tattcagagt gaataacaat
    20221 gacctgcctt taattaaaac tattggaaat acgtcgaaat aggtatatat gccaggataa
    20281 accaatatat tttttatgga tattcatttt ccttcatcgg actgtaaatt gcggagatat
    20341 cgaacttgca ctacccatcg caacactcaa acagatttat gaatttcgtt cataacccct
    20401 gacaaattct gccgtctaat cgagcttttc cctttacgtt atgcttctca tgaacgataa
    20461 cacaacttgt tcatgaatta accattccgg ataaactatg ggatcaaatt caggcatcga
    20521 aaggaactgg ctggtttccg ttaatggatt aaatatctat tattctcccg agagtaaaac
    20581 tatcaaatca atgagtaacc gatacagcct cacaaattct ttcagataat taacccgtca
    20641 ctgcggcacg ttctctcata aggcgtgcct gcagtgtaat ccagtatgta tccggcatag
    20701 ttgacggttt aatagaactc aattcctctc ccaagtcacc aacaacgata tcttgtataa
    20761 caccccagga gatacgacat tatgatgaga tgcgatatgc tcctcagcac caatcaacgc
    20821 ccggactggg ccagtcttga gatcagactc attcccggaa ctgacttcag gcgacatata
    20881 tcaatgacgt tggtgcaata aaagatagtt gatgtaatac atctattcaa atttgtgata
    20941 catgtcaaaa aactggttga ccaaactcgt tatttatata agggcactta cgaagtgcac
    21001 tcttttttaa agcgaggaag taccaatgaa agagaataaa gtacagcaaa tcagtcataa
    21061 actgattaat atcgttgttt ttgtcgcaat tgtagaatac gcctatttat ttctccattt
    21121 ctattaataa cggaaataaa ctgttcactt cagtgatatt taaaatatgc atcctctccc
    21181 ttttttgtaa gtaattatta tatccgtggg agaggaatac acgctgtcag gtaatcaatc
    21241 atactgcgat aaattatcgg ccagtaaagt ggagataacc tccattctcg aaaaatccat
    21301 actctcagca aaaccatcat caatcactca tccaggcgtt tatgggagcg tcaccaatgg
    21361 ctgctaacaa tgccagagtt ccccgttgcg aaaattccac atccacaaag agtcacaggg
    21421 attgagtgtt gaaatgatcc ggatgagcat gtatctttat ggttatgtta taacataaca
    21481 ggtaaaaatg atgaagccca atatccatcc tgagtatcgt actgtggtgt tccacgacac
    21541 cagtgttgat gagtacttta aaatcggctc gactatcaaa acagaccgtg agattgagct
    21601 ggatggcgta acgtatccat acgtgacaat tgatgtctct tctaaatcgc acccgttcta
    21661 tacagggaag ctgagaacag tggcatcaga aggaaatgtt gcacgattca cccaacgttt
    21721 tggtcgtttt gttagcacga aaaagggggc gtgatgaaag ttcttaactc tctgcgtacc
    21781 gcaaaagaac gccatccaga ctgtcagatt gtgaagcgaa aaggacggct atatgtgatt
    21841 tgtaaatcta atccacgttt taaggccgtt cagggtcgta agaaaaaacg ttgattcaaa
    21901 attcgacgga ttaacgatat ttgtctgatt aataatcaga tcggattaat gttggtgtgt
    21961 ttataacacc aacattaatt ttcctgggga tatattcttc ctgttcattt gaggccaact
    22021 gcctgacgtt tctctccgaa tattccatta tcttaatgtt gacttgttga ccagcttcgc
    22081 ccctgtatgc tggcatcaac cctcttttag actgaacacg ccactcagtc tcctcccttt
    22141 gcggcgcagc ctgcattttc actcaaactg ttaagatgat aaatgtggta aatctgttgg
    22201 tactaacata aaaacgttta cgccacagga acagtctgat ccaccggtaa ccccgtcgcc
    22261 gacgttcgag tgccagttag agtaacgcgc acagataact gaatgcagtg ccctgacaaa
    22321 aaggccatcg ttcctgtgac agctggcagc cttcgtttaa cttcacttaa tctggctctt
    22381 gggggcttac cgaacagatg acgtacatac gcccgttcaa ttttccatta cttattggaa
    22441 tgaacacctg taaccatttt gtgcggcatg ttaatccatt aaaatatctt actgattggc
    22501 aaatcatctt caatgacagc tcatcatagt tttatattct atcccttacc cttaaaactt
    22561 gtttttttac tagtccatca cacagcgcat taagactatt cctaacactt cagggcaaag
    22621 ttcctgacca atataaaatg caagtaagaa ttgaacgtta tattgccaat aaccttatga
    22681 aaccaaatgt ctttttcttc ttatcaaaaa agcaatattt tcagtttttc taaatattga
    22741 cttaaccatt gaattccttt tccgttcaca tattgacact catcgggaaa aaaaacataa
    22801 atttaagccc aatcgaaaat aattaaactt aatctcgttt aacctttatt gatatgtact
    22861 acgtatctta tttacttccg gtttactaag gaaactgaat gcacctgtaa aaattacagg
    22921 tttggaaagt agtgacatgg caaagtgatt acagtaggga ctatgaggtt aaaaaccata
    22981 tggaatgtca aaaccgttct gataaataca tctggtctcc ccatgacgcc tacttctata
    23041 aaggactatc tgaactgatt gtggatatcg acagattaat ttatctatcg ttggagaaaa
    23101 ttagaaaaga tttcgtgttt atcaatctca gtacggattc tttatctgaa tttataaacc
    23161 gtgataatga atggttatcc gcggtaaagg ggaaacaggt cgtattgatt gcggccagaa
    23221 agtcagaggc cttagcaaat tattggtatt acaatagcaa tattaggggc gtggtatacg
    23281 ctggactgag tcgtgatatt agaaaagaac tggtctatgt gattaatggc aggttcctga
    23341 gaaaagatat taagaaagat aaaatcacgg accgggaaat ggaaattatc cgcatgacgg
    23401 cccagggaat gcaacctaaa tcgattgcca gaattgaaaa ttgtagtgtg aagacagtgt
    23461 atacccatcg gcgtaatgct gaggccaagc tgtactcaaa aatatataag ttggttcagt
    23521 aaactccagg caagttagtt ttaaaaaatg actcactggg acatcacgtc ctcaattcaa
    23581 ctcgggaaga aatgcaatga aaaaaaaggt tctggcaata gctctggtaa cggtgtttac
    23641 cggcatgggt gtggcgcagg ctgctgacgt aacagctcag gctgtagcga cctggtcggc
    23701 aacagccaaa aaagacacca ccagtaagct ggttgtgacg ccactcggta gcctggcgtt
    23761 ccagtatgcc gaaggcatta aaggttttaa ctcacagaaa ggtctatttg acgtggctat
    23821 cgagggtgac tcaacggcta ccgcctttaa actgacctca cgtcttatca ccaacacatt
    23881 aacccagttg gatacctcag gttccacact gaatgtgggc gtggattata acggcgcggc
    23941 agtcgaaaaa actggcgata ccgtgatgat cgataccgcc aacggcgtac tgggcggcaa
    24001 ccttagcccg ctggctaacg gttacaatgc cagcaatcgt accaccgcac aggatggttt
    24061 caccttctcc atcatcagcg gtaccaccaa tggtaccacc gcagtaacag attacagcac
    24121 tctaccggaa ggcatctgga gcggcgacgt tagcgtacag ttcgacgcga cctggaccag
    24181 ttaatctctc tgatgtacca gcaggggtag cccccctgct ttattcctgg acggaattgt
    24241 tatgaaaaag caccttctgc ctctcgctct gctgttttcc ggaatatctc cggcccaggc
    24301 gctggatgtc ggcgatatat catcgtttat gaacagtgac agcagcacgc tgagcaaaac
    24361 gatcaaaaac agtaccgaca gtggtcgcct tatcaatatc cgtctcgaac ggctctcttc
    24421 accgcttgac gacgggcagg ttatctcaat ggacaagccg gatgagttgc tactcactcc
    24481 cgccagcttg ctgctacccg cccaagccag cgaagtgatc cgcttcttct ataagggacc
    24541 cgcagatgaa aaagagcgct actaccgcat tgtctggttt gatcaggccc tcagtgatgc
    24601 gcagcgcgat aatgccaacc gcagcgctgt ggccactgct tccgcccgca tcggcaccat
    24661 tctggtcgtc gcccctcgtc aggcgaacta ccactttcag tacgccaacg gctccctgac
    24721 aaatacagga aatgcgacgc tgcggatcct cgcctacgga ccttgcctga aagccgccaa
    24781 cggtaaggag tgtaaagaga attactacct gatgccgggc aagtcgcgtc gttttacccg
    24841 cgtggacact gcggataaca aaggacgggt tgcactttgg cagggtgata agttcattcc
    24901 cgtgaaatag atagctgtgc agatggataa cgacaatgcc tttacgacgg ttctccccag
    24961 gactgaaagc ccagtttgcc ttcggcatgg tctttttgtt cgttcagccc gatgccagcg
    25021 ctgctgacat aagtgcgcag caaataggtg gggtgattat tccgcaggcc ttcagtcagg
    25081 cgcttcagga cggcatgagc gtcccgctct atattcatct cgccggtagc cagggtcgcc
    25141 aggacgatca gcgaatcggc agcgctttta tctggctgga cgatggacag ctacgcatcc
    25201 ggaaaataca gctggaagag agtgaagata acgccagtgt cagcgaacaa actcgacagc
    25261 agctgatggc tctggccaac gccccgttca atgaggccct taccatcccc ctgactgaca
    25321 acgcgcagct ggatctcagc ttgcgccaac tgctgctgca gctagtggtc aagcgcgaag
    25381 cgctgggcac cgtactacgc tcacgtagcg aagacatcgg gcagtccagt gttaacaccc
    25441 tcagcagtaa tctgagctat aacttgggcg tctataacaa ccagttgcgt aacggcggga
    25501 gcaacacatc cagctatctg tcgctgaata acgttactgc actgcgcgaa catcatgtgg
    25561 tgctcgacgg ctcgctgtac gggatcggta gcggtcaaca ggacagtgaa ttatataaag
    25621 cgatgtatga acgcgatttt gccggtcacc gatttgccgg tggaatgctc gacacctgga
    25681 acttgcagtc cttagggccg atgaccgcca tttcagcagg gaagatttac ggcctttcct
    25741 ggggaaacca ggccagctcc accatcttcg acagcagcca gtcagccacg ccagtgatcg
    25801 cctttttacc ggcggcgggc gaagtacatc tcacccgtga tgggcggcta ctaagcgttc
    25861 agaacttcac tatgggcaat catgaagtgg atacccgggg tctaccgtac gggatttacg
    25921 atgtggaagt tgaggtgatc gttaacggtc gcgtgatcag caaacgcacc cagcgggtca
    25981 ataagctgtt tagccggggg cgcggcgtcg gtgcaccact ggcgtggcag gtatggggcg
    26041 gtagctttca tatggatcgc tggtcggaaa acgggaaaaa gacgcgacca gctaaagaga
    26101 gttggctagc aggtgcctcg acctccggct cattgagtac gcttagctgg gcggcaacgg
    26161 gatatggata cgataatcag gcggtgggtg aaacccgtct gacgctgccg cttggggggg
    26221 cgatcaacgt taacctgcaa aatatgctgg ccagtgacag ctcatggagc agcatcggca
    26281 gcatcagcgc cactctaccg ggaggcttta gttcgctgtg ggttaatcag gaaaaaaccc
    26341 gcattggcaa tcaattgcga cgtagcgatg ccgacaaccg
//
LOCUS       DAPOAV010000062        26120 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.062, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000062 DAPOAV010000000
VERSION     DAPOAV010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26120
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.062"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(146..226)
                     /gene="shoB"
                     /locus_tag="RN951_002933"
     CDS             complement(146..226)
                     /gene="shoB"
                     /locus_tag="RN951_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin ShoB"
                     /protein_id="HDX2527905.1"
                     /translation="MTDCRYLIKRVIKIIIAVLQLILLFL"
     gene            complement(646..1026)
                     /locus_tag="RN951_002934"
     CDS             complement(646..1026)
                     /locus_tag="RN951_002934"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HDX2527906.1"
                     /translation="MAILGLGTDIVEIARIEAVIARSGERLARRVLSDNEWAIWKTHH
                     QPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALKLAEKL
                     GVVNMHVTLADERHYACATVIIES"
     gene            complement(1026..1757)
                     /gene="pdxJ"
                     /locus_tag="RN951_002935"
     CDS             complement(1026..1757)
                     /gene="pdxJ"
                     /locus_tag="RN951_002935"
                     /EC_number="2.6.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="HDX2527907.1"
                     /translation="MAELLLGVNIDHIATLRNARGTAYPDPVQAAFIAEQAGADGITV
                     HLREDRRHITDRDVRILRQTLDTRMNLEMAVTEEMLAIAVETKPHFCCLVPEKRQEVT
                     TEGGLDVAGQRDKMRDACKRLADAGIQVSLFIDADEEQIKAAAEVGAPFIEIHTGCYA
                     DAKTDAEQAQELARIAKAAIFAASLGLKVNAGHGLTYHNVKAIAAIPEMHELNIGHAI
                     IGRAVMTGLKDAVAEMKRLMLEARG"
     gene            complement(1769..2497)
                     /gene="recO"
                     /locus_tag="RN951_002936"
     CDS             complement(1769..2497)
                     /gene="recO"
                     /locus_tag="RN951_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HDX2527908.1"
                     /translation="MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRS
                     TLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEY
                     ETRFSELFFDYLHCIQSLAGATGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDD
                     TMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLG
                     GKPLKSRELFRQFMPKRTVKTHYE"
     gene            complement(2509..3414)
                     /gene="era"
                     /locus_tag="RN951_002937"
     CDS             complement(2509..3414)
                     /gene="era"
                     /locus_tag="RN951_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HDX2527909.1"
                     /translation="MSIDKSYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTR
                     HRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWT
                     PDDEMVLNKLRDGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGL
                     NVDTIAAIVRKHLPEATHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEI
                     ERFVSNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLE
                     LWVKVKSGWADDERALRSLGYVDDL"
     gene            complement(3411..4091)
                     /gene="rnc"
                     /locus_tag="RN951_002938"
     CDS             complement(3411..4091)
                     /gene="rnc"
                     /locus_tag="RN951_002938"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004248457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HDX2527910.1"
                     /translation="MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLG
                     DSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELK
                     SGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRL
                     QEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQ
                     ALKKLELE"
     gene            complement(4363..5337)
                     /gene="lepB"
                     /locus_tag="RN951_002939"
     CDS             complement(4363..5337)
                     /gene="lepB"
                     /locus_tag="RN951_002939"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDX2527911.1"
                     /translation="MANMFALILVIATLVTGILWCVDKFFFAPKRRERQAAAQAAAGD
                     SLDKATLKKVAPKPGWLETGASVFPVLAIVLIVRSFIYEPFQIPSGSMMPTLLIGDFI
                     LVEKFAYGIKDPIYQKTLIETGHPKRGDIVVFKYPEDPKLDYIKRAVGLPGDKVTYDP
                     VSKELTIQPGCSSGQACENALPVTYSNVEPSDFVQTFSRRNGGEATSGFFEVPKNETK
                     ENGIRLSERKETLGDVTHRILTVPIAQDQVGMYYQQPGQQLATWIVPPGQYFMMGDNR
                     DNSADSRYWGFVPEANLVGRATAIWMSFDKQEGEWPTGVRLSRIGGIH"
     gene            complement(5353..7152)
                     /gene="lepA"
                     /locus_tag="RN951_002940"
     CDS             complement(5353..7152)
                     /gene="lepA"
                     /locus_tag="RN951_002940"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HDX2527912.1"
                     /translation="MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSM
                     DLERERGITIKAQSVTLDYKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVV
                     DAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVR
                     CSAKTGVGVQDVLERLVRDIPPPEGDPEGPLQALIIDSWFDNYLGVVSLIRIKNGTLR
                     KGDKVKVMSTGQTYNADRLGIFTPKQVDRTELKCGEVGWLVCAIKDIHGAPVGDTLTL
                     ARNPAEKALPGFKKVKPQVYAGLFPVSSDDYEAFRDALGKLSLNDASLFYEPESSSAL
                     GFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTSREVIYVDSPSKLPA
                     VNNIYELREPIAECHMLLPQAYLGNVITLCVEKRGVQTNMVYHGNQVALTYEIPMAEV
                     VLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINGERVDALALITHRDNSQNRG
                     RELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQ
                     KQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK"
     gene            complement(7350..7829)
                     /gene="rseC"
                     /locus_tag="RN951_002941"
     CDS             complement(7350..7829)
                     /gene="rseC"
                     /locus_tag="RN951_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR-reducing system protein RseC"
                     /protein_id="HDX2527913.1"
                     /translation="MIKEWATVVSWQNGQALVSCDVKASCSSCASRAGCGSRVLNKLG
                     PQTTHTIVVPCDEPLVPGQKVELGIAEGSLLSSALLVYMSPLVGLFLIASLFQLLFAS
                     DVAALCGAVLGGIGGFLIARGYSRKFAARAEWQPIILSVALPPGLVRFETSSEDASQ"
     gene            complement(7826..8782)
                     /gene="rseB"
                     /locus_tag="RN951_002942"
     CDS             complement(7826..8782)
                     /gene="rseB"
                     /locus_tag="RN951_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E factor regulatory protein RseB"
                     /protein_id="HDX2527914.1"
                     /translation="MKQLWFAMSLVTGSLLFSANASATPASGALLQQMNLASQSLNYE
                     LSFISINKQGVESLRYRHARLDNRPLAQLLQMDGPRREVVQRGNEISYFEPGLEPFTL
                     NGDYIVDSLPSLIYTDFKRLSPYYDFISVGRTRIADRLCEVIRVVARDGTRYSYIVWM
                     DTESKLPMRVDLLDRDGETLEQFRVIAFNVNQDISSSMQTLAKANLPPLLSVPVGEKA
                     KFSWTPTWLPQGFSEVSSSRRPLPTMDNMPIESRLYSDGLFSFSVNVNRATPSSTDQM
                     LRTGRRTVSTSVRDNAEITIVGELPPQTAKRIAENIKFGAAQ"
     gene            complement(8782..9432)
                     /gene="rseA"
                     /locus_tag="RN951_002943"
     CDS             complement(8782..9432)
                     /gene="rseA"
                     /locus_tag="RN951_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-E factor RseA"
                     /protein_id="HDX2527915.1"
                     /translation="MQKEQLSALMDGETLDSELLNELAHNPEMQKTWESYHLIRDSMR
                     GDTPEVLHFDISSRVMAAIEEEPVRQPATLIPEAQPAPHQWQKMPFWQKVRPWAAQLT
                     QMGVAACVSLAVIVGVQHYNGQSETSQQPETPVFNTLPMMGKASPVSLGVPSEATANN
                     GQQQQVQEQRRRINAMLQDYELQRRLHSEQLQFEQAQTQQAAVQVPGIQTLGTQSQ"
     gene            complement(9465..10040)
                     /gene="rpoE"
                     /locus_tag="RN951_002944"
     CDS             complement(9465..10040)
                     /gene="rpoE"
                     /locus_tag="RN951_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005070454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoE"
                     /protein_id="HDX2527916.1"
                     /translation="MSEQLTDQVLVERVQKGDQKAFNLLVVRYQHKVASLVSRYVPSG
                     DVPDVVQEAFIKAYRALDSFRGDSAFYTWLYRIAVNTAKNYLVAQGRRPPSSDVDAIE
                     AENFESGGALKEISNPENLMLSEELRQIVFRTIESLPEDLRMAITLRELDGLSYEEIA
                     AIMDCPVGTVRSRIFRAREAIDNKVQPLIRR"
     gene            complement(10037..10192)
                     /gene="rseD"
                     /locus_tag="RN951_002945"
     CDS             complement(10037..10192)
                     /gene="rseD"
                     /locus_tag="RN951_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rpoE leader peptide RseD"
                     /protein_id="HDX2527917.1"
                     /translation="MIRLQHDKQKQMRYGTLQKRDTLILCLLKLQLMEWRFDSAWKFG
                     LGRLYLG"
     gene            10448..12070
                     /gene="nadB"
                     /locus_tag="RN951_002946"
     CDS             10448..12070
                     /gene="nadB"
                     /locus_tag="RN951_002946"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HDX2527918.1"
                     /translation="MNTLPEHSCDVLIIGSGAAGLSLALRLADQHQVIVLSKGPVTEG
                     STFYAQGGIAAVFDETDSIDSHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQGV
                     LFDTHVQPNGEESYHLTREGGHSHRRILHAADATGREVQSTLVSKAQNHPNIRVLERS
                     NAVDLIVSDKIGLPGTRRVVGAWVWNRNKETVETCHAKAVVLATGGASKVYQYTTNPD
                     ISSGDGIAMAWRAGCRVANLEFNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDGTR
                     FMPDFDERGELAPRDIVARAIDHEMKRLGADCMFLDISHKPADFIRQHFPMIYEKLLG
                     LGIDLTQEPIPIVPAAHYTCGGVMVDDHGRTDVEGLYAIGEVSYTGLHGANRMASNSL
                     LECLVYGWSAAEDITRRMPYAHGVSTLPPWDESRVENPDERVVIQHNWHELRLFMWDY
                     VGIVRTTKRLERALRRITMLQQEIDEYYAHFRVSNNLLELRNLVQVAELIVRCAMMRK
                     ESRGLHFTLDYPELLTHSGPSILSPGNHYINR"
     gene            complement(12055..12792)
                     /gene="trmN"
                     /locus_tag="RN951_002947"
     CDS             complement(12055..12792)
                     /gene="trmN"
                     /locus_tag="RN951_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417070.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(1)(Val)
                     (adenine(37)-N(6))-methyltransferase TrmN"
                     /protein_id="HDX2527919.1"
                     /translation="MSQSTSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAG
                     VKRCLDIGAGSGLLALMLAQRTDDSVIIDAVELESEAAAQAQENINQSPWAERINVHT
                     ADIQQWITQQTVRFDLIISNPPYYQQGVECATPQREQARYTTTLDHPSLLTCAAECIT
                     EEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFS
                     DRLVIRGPDQNYSEAYTALTQAFYLFM"
     gene            12924..14258
                     /gene="srmB"
                     /locus_tag="RN951_002948"
     CDS             12924..14258
                     /gene="srmB"
                     /locus_tag="RN951_002948"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase SrmB"
                     /protein_id="HDX2527920.1"
                     /translation="MTVTTFSELELDESLLEALQDKGFTRPTAIQAAAIPPALDGRDV
                     LGSAPTGTGKTAAYLLPALQHLLDFPRKKSGPPRILILTPTRELAMQVADHARELAKH
                     THLDIATITGGVAYMNHAEVFSENQDIVVATTGRLLQYIKEENFDCRAVETLILDEAD
                     RMLDMGFAQDIEHIAGETRWRKQTLLFSATLEGDAIQDFAERLLEDPVEVSANPSTRE
                     RKKIHQWYYRADDLEHKTALLVHLLKQPEATRSIVFVRKRERVHELANWLREAGINNC
                     YLEGEMVQGKRNEAIKRLTEGRVNVLVATDVAARGIDIPDVSHVFNFDMPRSGDTYLH
                     RIGRTARAGRKGTAISLVEAHDHLLLGKVGRYIEEPIKARVIDELRPKTRAPSEKQTG
                     KPSKKVLAKRAEKKKVKEKEKPRVKKRHRDTKNIGKRRKPSGTGVPPQTTEE"
     gene            complement(14291..15172)
                     /locus_tag="RN951_002949"
     CDS             complement(14291..15172)
                     /locus_tag="RN951_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417072.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX2527921.1"
                     /translation="MDLRRFITLKTVVEEGSFLRASQKLCCTQSTVTFHIQQLEQEFS
                     VQLFEKIGRRMCLTREGKKLLPHIYELTRVMDTLREAAKKESDPDGELRVVSGETLLS
                     YRMPQVLQRFRQRAPKVRLSLQSLNCYVIRDALLNDEADVGVFYRVGNDDVLNRRELG
                     EQPLVLVASPQIADIDFTEPGRHNACSFIINEPQCVFRQIFESTLRQRRITVENTIEL
                     ISIESIKRCVAANIGVSYLPRFAVGNELASGELIELPFGEQTQTITAMCAHHAGKAVS
                     PAMHTFIQCVEECFVAG"
     gene            15275..15862
                     /gene="eamB"
                     /locus_tag="RN951_002950"
     CDS             15275..15862
                     /gene="eamB"
                     /locus_tag="RN951_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/O-acetylserine transporter"
                     /protein_id="HDX2527922.1"
                     /translation="MTPTLLSAFWTYTLITAMTPGPNNILALSSATSHGFRQSTRVLA
                     GMSLGFLIVMLLCAGISFSLAVIDPAAVHLLSWAGAAYIVWLAWKIATSPTKEDGLQA
                     KPISFWASFALQFVNVKIILYGVTALSTFVLPQTQALSWVVGVSVLLAMIGTFGNVCW
                     ALAGHLFQRLFRQYGRQLNIVLALLLIYCAVRIFY"
     gene            complement(15917..16300)
                     /gene="grcA"
                     /locus_tag="RN951_002951"
     CDS             complement(15917..16300)
                     /gene="grcA"
                     /locus_tag="RN951_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007728348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autonomous glycyl radical cofactor GrcA"
                     /protein_id="HDX2527923.1"
                     /translation="MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGYAEDEVV
                     AVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSG
                     YAVRFNSLTPEQQRDVIARTFTESL"
     gene            16605..17294
                     /gene="ung"
                     /locus_tag="RN951_002952"
     CDS             16605..17294
                     /gene="ung"
                     /locus_tag="RN951_002952"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDX2527924.1"
                     /translation="MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDV
                     FNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIATPPSLLNMYKELENTIPG
                     FTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVV
                     FLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPI
                     DWMPVLPAESE"
     gene            complement(17342..18379)
                     /locus_tag="RN951_002953"
     CDS             complement(17342..18379)
                     /locus_tag="RN951_002953"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HDX2527925.1"
                     /translation="MNDEMKGKSGKVKVMYVRSDDDSDKRTHNPRTGKGGGRPGKSRA
                     DGGRRPARDDKQSQPRDRKWEDSPWRTVSRAPGDETPEKADHGGISGKSYIDPEVLRR
                     QRAEETRVYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEA
                     ELTKASGTEHHGGVCFLIKKRNGTTVQQWVSQAGAQDCVLALENESNPHNLGGMMRSC
                     AHFGVKGVVVQDAALLESGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTS
                     SEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGV
                     LLGEWWRQNKA"
     gene            18586..19005
                     /gene="trxC"
                     /locus_tag="RN951_002954"
     CDS             18586..19005
                     /gene="trxC"
                     /locus_tag="RN951_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxC"
                     /protein_id="HDX2527926.1"
                     /translation="MNTVCTHCQAINRIPDDRIEDAAKCGRCGHDLFDGEVINATGET
                     LDKLLKDDLPVVIDFWAPWCGPCRNFAPIFEDVAQERSGKVRFVKVNTEAERELSSRF
                     GIRSIPTIMIFKNGQVVDMLNGAVPKAPFDSWLNESL"
     gene            19074..19772
                     /gene="tapT"
                     /locus_tag="RN951_002955"
                     /gene_synonym="tuaA"
                     /gene_synonym="yfiP"
     CDS             19074..19772
                     /gene="tapT"
                     /locus_tag="RN951_002955"
                     /gene_synonym="tuaA"
                     /gene_synonym="yfiP"
                     /EC_number="2.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311476.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-uridine aminocarboxypropyltransferase"
                     /protein_id="HDX2527927.1"
                     /translation="MTENAVLQLRAERIARATRPFLARGNRVRRCQRCLLPEKLCLCS
                     TITPAQAKSRFCLLMFDTEPMKPSNTGRLIADILPDTVAFQWSRTEPSQDLLDLVQNP
                     DYQPMVVFPASYADEQREVIFTPPAGKPPLFIMLDGTWPEARKMFRKSPYLDNLPVIS
                     VDLSRLSAYRLREAQAEGQYCTAEVAIALLDMAGDTGAAAGLGEHFTRFKTRYLAGKT
                     QHLGSITAEQLESV"
     gene            19804..22464
                     /gene="pat"
                     /locus_tag="RN951_002956"
     CDS             19804..22464
                     /gene="pat"
                     /locus_tag="RN951_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein lysine acetyltransferase"
                     /protein_id="HDX2527928.1"
                     /translation="MSQRGLEALLRPKSIAVIGASMKPNRAGYLMMRNLLAGGFNGPV
                     LPVTPAWKAVLGVLAWPDIASLPFTPDLAVLCTNASRNLALLEELGEKGCKTCIILSA
                     PASQHEDLRACALRHNMRLLGPNSLGLLAPWQGLNASFSPVPIKRGKLAFISQSAAVS
                     NTILDWAQQREMGFSYFIALGDSLDIDVDELLDYLARDSKTSAILLYLEQLSDARRFV
                     SAARSASRNKPILVIKSGRSPAAQRLLNTTAGMDPAWDAAIQRAGLLRVQDTHELFSA
                     VETLSHMRPLRGDRLMIISNGAAPAALALDALWSRNGKLATLSEETCQKLRDALPGHV
                     AISNPLDLRDDASSEHYIKTLDILLHSQDFDALMVIHSPSAAAPATESAQVLIEAVKH
                     HPRSKYVSLLTNWCGEHSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLR
                     ETPALPSNLTSNTAEAHLLLQQAIAEGATSLDTHEVQPILQAYGMNTLPTWIASDSTE
                     AVHIAEQIGYPVALKLRSPDIPHKSEVQGVMLYLRTANEVQQAANAIFDRVKMAWPQA
                     RVHGLLVQSMANRAGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEDQAVVALPPLNMN
                     LARYLVIQGIKSKKIRARSALRPLDVAGLSQLLVQVSNLIVDCPEIQRLDIHPLLASG
                     SEFTALDVTLDISPFEGDNESRLAVRPYPHQLEEWVELKNGERCLFRPILPEDEPQLQ
                     QFISRVTKEDLYYRYFSEINEFTHEDLANMTQIDYDREMAFVAVRRIDQTEEILGVTR
                     AISDPDNIDAEFAVLVRSDLKGLGLGRRLMEKLITYTRDHGLQRLNGITMPNNRGMVA
                     LARKLGFNVDIQLEEGIVGLTLNLAQREES"
     gene            22578..23933
                     /gene="pssA"
                     /locus_tag="RN951_002957"
     CDS             22578..23933
                     /gene="pssA"
                     /locus_tag="RN951_002957"
                     /EC_number="2.7.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--serine
                     O-phosphatidyltransferase"
                     /protein_id="HDX2527929.1"
                     /translation="MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKI
                     ASAKQRICIVALYLEQDDGGKGILNALYEAKRQRPELDVRVLVDWHRAQRGRIGAAAS
                     NTNADWYCRMAQENPGVDVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYL
                     HQHDKYRYDRYHLIRNRKMSDIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLF
                     RQELRDAAYHFQGDADNDQLSVTPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNL
                     PAILVRNIIQLLREGKKVEIIVGDKTANDFYIPEDEPFKIIGALPYLYEINLRRFLSR
                     LQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWMLITGNNLNPRAWRLDLENAILIHD
                     PQLELAPQREKELELIREHTTIVKHYRDLQSIADYPVKVRKLIRRLRRIRIDRLISRI
                     L"
     gene            23979..24302
                     /locus_tag="RN951_002958"
     CDS             23979..24302
                     /locus_tag="RN951_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417081.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiM family lipoprotein"
                     /protein_id="HDX2527930.1"
                     /translation="MRILFVCSLLLLSGCSHMANDSWSGQDKAQHFIASAMLSAAGNE
                     YSQHQGMSRDRSAMFGLMFSVSLGASKELWDSRPEGSGWSWKDLAWDVAGASTGYTVW
                     QLTRH"
     gene            complement(24299..25597)
                     /gene="kgtP"
                     /locus_tag="RN951_002959"
     CDS             complement(24299..25597)
                     /gene="kgtP"
                     /locus_tag="RN951_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoglutarate permease"
                     /protein_id="HDX2527931.1"
                     /translation="MAESTVTADSKLTSSDTRRRIWAIVGASSGNLVEWFDFYVYSFC
                     SLYFAHIFFPSGNTTTQLLQTAGVFAAGFLMRPIGGWLFGRIADKHGRKKSMLLSVCM
                     MCFGSLVIACLPGYETIGTWAPALLLLARLFQGLSVGGEYGTSATYMSEVAVEGRKGF
                     YASFQYVTLIGGQLLALLVVVVLQHTMEDAALREWGWRIPFALGAVLAVVALWLRRQL
                     DETSQQETRALKEAGSLKGLWRNRRAFIMVLGFTAAGSLCFYTFTTYMQKYLVNTAGM
                     HANVASGIMTAALFVFMLIQPLIGALSDKIGRRTSMLCFGSLAAIFTVPILSALQNVS
                     SPYAAFGLVMCALLIVSFYTSISGILKAEMFPAQVRALGVGLSYAVANAIFGGSAEYV
                     ALSLKSIGMETAFFWYVTLMAVVAFLVSLMLHRKGKGMRL"
     gene            complement(25923..26038)
                     /gene="rrf"
                     /locus_tag="RN951_002960"
     rRNA            complement(25923..26038)
                     /gene="rrf"
                     /locus_tag="RN951_002960"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         6292 a         6893 c         6516 g         6419 t
ORIGIN      
        1 acgccattat atttatttaa ttgatgacat tagcataatc attcactaag ttaatttata
       61 tagtatctgc caagacactt atttatagtt attaaaggcg cgtccgattg gttcaccgga
      121 cgcaccttaa gtacgtttcc ttgtgttata agaacagaag gatcagctgt aaaacagcaa
      181 tgatgatttt gatgacccgt ttaatcaggt atcggcaatc agtcattcgt ttttccttaa
      241 acaaggaatg cagccgttca gattagccct tacatctccc caaaactgaa cgtgcgagtt
      301 attgagggtg catgctgcac tccacaccag agctttgacg acaccactcg tttcaatggg
      361 ggaattctgt ggcatggtgt aaagcacagc aaaatcttca ataacgaagc caattttaat
      421 gtacttacga attggcggtc acgttaatct ttccatcaat attgctttct tcgtaaaggc
      481 tcgagttttt atgctaaaga ttgcaagttg cttgtaaaag ataagtacac tgatccataa
      541 tcgctgttgt tgagggtgca tgctgcacaa aattaaagtt aaaaagtaaa acccccgttc
      601 cttaccagtt cgggggtttt actttttaaa gagaacggta ttattttaac tttcaataat
      661 taccgtggca caagcatagt ggcgttcatc tgccagcgtt acatgcatat ttacaacgcc
      721 gagcttttcc gccagtttta atgcctcacc ccatagccgt agccgtggtt tgccgagctc
      781 atcattgaat acttcaaatt gattaaacgc cagaccattg cggatcccgg tgccaaacgc
      841 ttttgctgcg gcttctttca cagcaaaacg cttcgccaga aaacgcaccg gctggtggtg
      901 cgttttccag attgcccatt cgttatcgct taatacgcgg cgtgccaggc gctcaccgga
      961 tcgggcgatc actgcttcta tgcgagcgat ctctacgata tccgtgccta aacctaatat
     1021 tgccattagc cacgcgcttc cagcatcaga cgcttcattt ctgccaccgc atctttcagt
     1081 ccggtcatca ctgcacgacc aataatggca tgaccgatat tcagttcatg catctcaggg
     1141 atggcggcaa tagctttcac gttgtgatag gtcagaccgt gaccagcgtt aactttcaga
     1201 ccgagactag cggcaaagat cgcggctttg gcgatacgcg ccagctcttg cgcctgttcg
     1261 gcgtcagttt tggcatcagc atagcaaccg gtgtggatct cgataaacgg tgcgccaacc
     1321 tctgccgcag ctttgatctg ctcttcatcg gcgtcgataa agagagaaac ctggatcccg
     1381 gcatctgcca gacgtttgca ggcatcgcgc attttgtcac gctgccctgc gacgtccagg
     1441 ccgccttcgg ttgttacttc ctgacgcttt tccggtacca gacagcaaaa atgtggcttc
     1501 gtctcaacgg cgatcgccag catctcttcg gtcaccgcca tctccagatt catgcgggta
     1561 tccagtgtct gacgcaggat gcgcacatca cggtcagtaa tgtggcggcg atcttcacgt
     1621 aaatgcacgg taatgccgtc cgctcccgcc tgctcagcaa taaacgccgc ctgcaccgga
     1681 tccgggtaag cagtaccgcg tgcgttacgc agcgttgcaa tatggtcaat gttgacgcct
     1741 aacagtaatt cagccatgac aatcctcatc attcataatg tgttttcacc gttcgcttag
     1801 gcataaactg ccggaacagt tccctgctct ttaatggttt accgccaaga tacggcttaa
     1861 gcgccatgcg ggtaaagcgt ttcgcggcgc gtagtgtgtc tgcgtcagga aattcccgcg
     1921 cgtttaacgc ttttaactgc cttccggtga acgttttatt gtcgataacg acgcttgcga
     1981 taaacccttt ttcttcgcga taacgatacg tcatggtgtc atctaccggc tcgccgctac
     2041 ccgcacaatg ggtaaaattg acgccatagc ccagatgccc gagcagtgcc agttcaaagc
     2101 ggcgcagcgc gggttctggc gtaccagtgg cacctgcaag agactgaatg cagtgcaagt
     2161 aatcgaaaaa gagttcagag aagcgcgtct cgtattccag tacgcgggag agaagttcgt
     2221 tgatgtacag accgctgtaa agcgtgatac cgcttaatgg cagcgccagc gagacagctt
     2281 cagcactgcg cagcgttttg acttcgccac gcccgccgaa acgtagcaag agaggggtga
     2341 aaggctgtaa tgcacctttc agagtagagc gtttagagcg tgcgcctttg gcaaccagac
     2401 gcacgcgacc cgattcctcc gtgaagacgt ccagcatcag gctggtttcg ctccacgggc
     2461 gactatgcag gacaaatgcg cgctgccagc cttccatcgg agtgactctt aaagatcgtc
     2521 aacgtaaccg agactgcgca gtgcgcgttc gtcgtcggcc caaccggatt tcacttttac
     2581 ccacagttca aggtggacag gcgcttcgaa catttcctgc atgtctttac gcgcttcaat
     2641 cccgatggtt ttgatcttgg cccctttgtt gccaataacc atcttcttct gcccttcacg
     2701 ctcaacgaga atcaaaccat tgatgtcata accaccgcgt tcgttagaga cgaaacgttc
     2761 gatctccacg gtcacggagt acggcagttc ggcgccgagg aaacgcatca gtttttcgcg
     2821 gatgatttca gacgccataa aacgctgtga gcgatcggtg atgtaatctt ccgggaagtg
     2881 atgggtcgct tcagggagat gcttacgcac gattgctgcg atagtgtcga cattcagccc
     2941 ggtttcagca gagatcggca cgatatcgag gaagttcatc tgacttgcca ggaactgtaa
     3001 gtgcggcagc agatcggctt tttcctgcac gttatccact ttgttcaccg cgaggatcac
     3061 cggcgctttg ccatcgcgca gtttgttgag caccatttcg tcgtccggcg tccagcgggt
     3121 gccttcaacg acaaaaatca ccagctcaac gtcgccaata gagctgctcg ccgctttgtt
     3181 catcaggcgg ttaatagcgc gtttttcttc catatgcagg ccaggggtat caacgtagat
     3241 cgcctgatac gcgccttcag tatggatccc cacaatgcgg tgacgagttg tttgcgcttt
     3301 gcgggaggtg atggagatct tctgccccag cagtttgttc aacaatgtgg atttgccaac
     3361 gttcggacgt ccgacgatgg caataaatcc gcagtaactt ttatcgatgc tcattccagc
     3421 tccagttttt tcaacgcctg ttcggcggca gcctgctcag ccttacgacg gcttgaacct
     3481 gtgccaacca ccggttcact caggccgctg acctggcagt ggatagtaaa ttcctgatcg
     3541 tgcgcttcgc cacgtacctg gactaccaga taagtcggca gcggcagatg gcgaccctgc
     3601 aaatattctt gcaagcgcgt tttcggatct ttttgtttat cgcctgggct aatttcgtcc
     3661 aaacgagttt gataccagtt gaggattaat ttctcgacgg tttgaatatc actgtcgagg
     3721 aatacgccac caattaatgc ttcgacggtg tcggcgagaa ttgactcacg acgaaatcca
     3781 ccgcttttaa gttcacctgg ccctaaacgt aagcactcgc ctaactcaaa ttcgcgcgcc
     3841 agttctgcca gcgtattgcc acggaccagc gtggcgcgca tccggctcat atcgccttca
     3901 tccacacgag ggaaacggtg ataaagcgca ttggcgataa cgtagctcag aatagagtcg
     3961 cctaaaaatt ctaaacgctc gttatgttta ctgctggcac tacgatgagt taatgcctgc
     4021 tgcaacagtt cctgatgatt aaaagtgtag cccagcttcc gttgaagccg attaattacg
     4081 atggggttca tgcgatacca ataaataaat gcgtcaacaa ttcagcacac gaaacagacc
     4141 tgatatacat ggctctgcta actgcttcgc tgcagtttca gtttaccggt atatggggac
     4201 caacgctgtt tcgtgtgccg tggcaacctg gaggtgccaa ccttaaactt cgggggaata
     4261 ttctatacac aacgacgggg gatgtcgtta gccacgggag atttatctca taaataattc
     4321 acgttgtcgc cataacggcg acaacgtgaa cgaagatggc tattaatgga tgccgccaat
     4381 gcgacttaag cgcacaccag tcggccattc gccttcttgc ttatcgaagc tcatccagat
     4441 agccgtggcc cgaccgacca gattcgcttc aggcacaaag ccccagtaac ggctgtccgc
     4501 gctgttgtcg cggttgtcgc ccatcatgaa gtattgtccc ggcggaacaa tccaggttgc
     4561 cagttgttgc cctggctgct ggtaatacat ccccacctgg tcctgcgcaa tcggcactgt
     4621 cagaattcgg tgcgtcacat cacccagtgt ctctttacgc tcggaaagac gaattccatt
     4681 ttctttggtt tcgtttttcg gcacttcaaa gaatccgctg gtcgcttccc caccattacg
     4741 gcgtgagaag gtctgaacga aatcgctcgg ttccacgttg gagtaggtga ccggtagcgc
     4801 gttttcacac gcctggccgg aactgcatcc cggttgaatc gtcagctctt ttgagaccgg
     4861 atcgtaagtg actttatcgc ccggtaaacc caccgcgcgc ttgatgtaat caagctttgg
     4921 atcttccgga tatttaaaga ccacgatatc gccgcgtttc ggatgaccgg tttcgatcag
     4981 cgttttctgg tagataggat ctttaatgcc ataagcaaac ttctctacca gaataaaatc
     5041 accgattaac agagtcggca tcatcgaacc tgacgggatc tggaacggtt cataaataaa
     5101 cgaacgtaca atcaatacga tagccagcac cggaaaaaca gaagcaccgg tttccagcca
     5161 gccaggcttc ggcgcaacct ttttcagggt tgctttatcc agtgagtcac cggcagccgc
     5221 ctgcgccgct gcctgacgtt cccgccgttt aggtgcgaaa aagaatttat ccacgcacca
     5281 taaaatgccc gtcaccagtg tggcaatcac cagaatcagg gcaaacatat tcgccatgcc
     5341 aactcctaag ggttatttgt tgtctttgcc gacgtgcaga atggcgagga acgcttcctg
     5401 cggcagctcg acgttaccga tctgcttcat gcgtttctta ccttctttct gcttctgcag
     5461 cagctttttc ttacggctga tatcgccgcc ataacattta gccagtacgt ttttacgcag
     5521 ctgtttcacg gtggatcgcg caataatgtg cgtaccaatc gctgcctgaa tggcgatatc
     5581 aaactgctgg cgtgggatca gatctttcat cttctccacc aactcgcgac cgcggttttg
     5641 cgaattatca cggtgggtga tcagcgccaa cgcatcaaca cgttcaccgt tgattaatac
     5701 gtctacacgt accatgtcgg acgcctggaa gcgtttgaag ttgtaatcca gagacgcata
     5761 accacgcgag gtagatttca ggcgatcgaa gaagtcgagc accacttccg ccatcgggat
     5821 ctcgtacgtc agcgccacct gattaccgtg gtaaaccata ttggtctgca cgccgcgttt
     5881 ttctacgcac agcgtaataa cgttgccgag atatgcctgc ggcagcagca tgtgacattc
     5941 ggcaatcggc tcgcgcagtt cgtagatgtt atttaccgct ggcagcttgg atggactgtc
     6001 gacgtaaata acttctcttg acgtggtttc aacttcatac actacggtcg gcgcagtggt
     6061 gatcagatcc agatcgtatt cacgttccag acgttcctgg atgatctcca tgtgcagcag
     6121 gccgaggaag ccgcagcgga aaccaaagcc cagcgcgctg gagctttccg gctcatagaa
     6181 cagtgaagca tcgttcaggc tgagtttacc cagcgcgtca cggaaggctt catagtcgtc
     6241 ggaacttacc gggaacagac cggcgtatac ctgcggtttg actttcttaa agccaggcag
     6301 cgccttttct gccggattac gcgccagcgt taaggtatcg ccgactggag cgccgtggat
     6361 atctttaatc gcacatacca gccagcctac ttcgccacat ttcagttcag tgcggtcaac
     6421 ctgtttcggc gtgaagatgc ccagacggtc ggcgttatag gtctgcccgg tactcatgac
     6481 tttcactttg tcgcccttac gcagggtgcc gtttttaata cggataagtg aaacaacgcc
     6541 caggtagttg tcgaaccatg agtcgataat tagtgcctgc aacgggcctt ccggatcgcc
     6601 ttccggcggc ggaatgtcgc gcaccagacg ttcgagaacg tcctgcacgc caacgccggt
     6661 tttcgctgaa cagcgcaccg cgtcggtggc gtcgatgccg acgatatctt caatttcttc
     6721 cgccacgcgt tcaggatcgg ctgccggcag gtcaatcttg ttcagtaccg gcaccacttc
     6781 gagatccatt tccatggcgg tgtagcagtt tgccagggtt tgcgcttcta cgccctgccc
     6841 ggcgtcgacc accagcaatg caccttcaca ggcagccagc gaacgggaaa cttcatagga
     6901 gaagtcaacg tggcccgggg tgtcgataaa gttcagctga taggtttcgc cgtcagacgc
     6961 tttgtagtcc agcgtcacgc tttgcgcttt gatggttatg ccacgctcac gctcaagatc
     7021 catggaatcg agaacctgcg cctccatttc acggtcagac aggccaccgc agatctggat
     7081 aatacggtca gacagcgtcg atttaccgtg gtcaatgtga gctatgatcg aaaagttacg
     7141 tatattcttc ataaagtatg attattgtgc cttaatgccc ggttaaccag gcttttagaa
     7201 gtcgctgttc tgagcttaac gtctgtatta atagaaacgc cgcattctac actacaacat
     7261 tgaggcgagg aaatgttcat accgtatgga ttgtggtatc tggaaacgtc ctcgcatttg
     7321 ttatgcaaaa tgcaacaaag ccagtgaaat cactggctcg cgtcttccga agatgtttca
     7381 aatcgcacaa ggccaggcgg caatgccacg cttaagatga tcggttgcca ttctgcccgg
     7441 gcagcaaact tacgcgagta gccgcgcgca atcaggaacc cgccaatacc gccgaggacc
     7501 gcaccacata atgctgcgac gtcagaagca aagagtagct gaaatagcga agcgatgagg
     7561 aataatccca ccagcggcga catataaacc agtaatgcgg agctaagcag gctgccttcg
     7621 gcgatcccca attccacttt ttgccccggc actaacggct catcacaggg tacgacaatg
     7681 gtatgcgtgg tttgcgggcc aagtttattt aacacgcggc taccgcaacc ggcgcgtgaa
     7741 gcgcagctgc tgcatgaagc tttaacatca caactgacca gcgcctgccc gttttgccag
     7801 gagacgacgg tagcccactc tttgatcatt gcgctgcccc gaacttaata ttctcggcaa
     7861 tgcgtttcgc cgtttgcggc ggcagttcac cgacaatggt gatttcggcg ttatcacgta
     7921 cgcttgtact gacggttctg cgtccggtgc gcaacatctg atcggtgctc gatggcgtag
     7981 cgcggttaac gtttaccgag aagctgaata atccgtcgga atagagacgt gattcgatag
     8041 gcatgttgtc catcgtcggt agcggacgtc gactactgga aacttcgcta aaaccctgtg
     8101 gcaaccaggt tggcgtccag ctgaatttag ctttttcacc tacaggaaca gaaagcaacg
     8161 gcggcaaatt tgccttcgcc agcgtctgca tactgctgct gatatcctga ttgacgttaa
     8221 aagcaatcac gcgaaattgt tccagcgttt caccatcgcg atcaaggaga tcaacccgca
     8281 tcggtaattt cgattcggtg tccatccaca cgatgtagct gtagcgtgta ccatctcggg
     8341 caaccacgcg aatgacttcg caaagacgat cagcaatacg cgtgcgcccg acggagataa
     8401 agtcgtagta aggagaaagg cgtttgaaat cggtatagat aagcgatggc agagaatcaa
     8461 caatgtaatc gccattaagc gtgaacggtt caagtcccgg ttcaaaatag ctgatttcat
     8521 tgccgcgctg taccacttcc cggcgcgggc catccatttg caacaattgt gcaagaggac
     8581 ggttatcgag gcgtgcatgt cgataacgca gagactcaac accctgttta ttgatgctga
     8641 tgaatgacag ctcgtaattc agtgactgac tggccaggtt catctgctgt aataacgccc
     8701 cggacgcggg agtggccgag gcgttagcag agaataacag gctacctgtc actaatgaca
     8761 tggcaaacca aagttgcttc attactgcga ttgcgttcct aaagtttgaa ttcctggcac
     8821 ctgtacagcg gcttgctggg tttgcgcctg ctcaaactga agctgttcag agtggagtcg
     8881 gcgttgcagt tcgtaatcct gcaacattgc attaatgcga cgacgctgct cctgtacctg
     8941 ctgctgttga ccattgtttg cggtcgcttc agaaggtact cccaggctta ccgggctggc
     9001 tttacccatc atcggcagtg tattaaatac cggcgtttcg ggctgctggg acgtttcaga
     9061 ttgtccatta tagtgctgga cgccaacgat aactgcaagc gatacgcatg ctgctacgcc
     9121 catttgggta agctgtgccg cccacggacg tactttctgc cagaatggca ttttctgcca
     9181 ttgatgcggc gcaggctggg cttccgggat caatgtcgcc ggttgacgta ctggctcttc
     9241 ttcaatggcg gccatcacgc gtgaagagat atcgaaatgg agcacctcgg gagtatcacc
     9301 ccgcattgag tcacggatta agtgatagct ttcccaggtt ttctgcattt ctgggttatg
     9361 agccagttcg ttaagcagct cactatccag cgtttcgcca tccattaaag cggaaagttg
     9421 ttctttctgc atgcctaata cccttatcca gtatcccgct atcgtcaacg cctgataagc
     9481 ggttgaactt tgttatcaat agcttccctc gctcggaaga tacgtgaacg caccgtacct
     9541 accggacaat ccatgatagc ggctatctct tcatagctca ggccatccag ctcccgcaag
     9601 gttattgcca tgcgcaaatc ttccgggagg gactcaatag ttcggaaaac tatctgtctc
     9661 agttcttctg acaacattaa gttctcaggg ttcgaaattt ctttcaacgc gccgccactt
     9721 tcgaagtttt cagcttcaat ggcatccaca tcactggaag gtggacgacg cccctgagca
     9781 accaggtaat ttttcgctgt atttacagca atccgataca gccatgtata aaaagcgcta
     9841 tctccccgga acgaatccag cgcacgatag gctttaataa aagcttcttg taccacatcg
     9901 ggaacatcac ccgacggcac atagcgggaa accagactcg ccactttatg ctgatagcgc
     9961 actaccagta ggttaaaggc tttctgatct cccttctgga cccgttcaac caggacctgg
    10021 tccgttaact gctcgctcat ccgaggtaaa gtctccccaa accaaatttc cacgcgctat
    10081 cgaaacgcca ctccattagc tgcaatttga gcaagcaaag gattagagtg tctcgttttt
    10141 gtaaagttcc gtaacgcatc tgtttttgtt tgtcatgctg tagacggatc attatctatc
    10201 attataagtc tacagaatct gaacatcgca ttatctgtgt agaaatgccc atttaactgc
    10261 ctgaagagta acccaacggc ctttttattt caccacctaa tcctccacca gccagtaact
    10321 tctctttttc tcgccgccct gcgtcagcgt gtttagccac tgtaacaaat attaaaatag
    10381 caggtgttta ttcgcacaac atgatgctat gctgaccaaa cggtgtttag taaattaaac
    10441 aaagaaaatg aatactctcc cagaacattc atgtgacgtg ttgattatcg gtagcggcgc
    10501 agccggactt tcactggcgc tacgcctggc tgaccagcat caggtcatcg ttctaagtaa
    10561 aggcccggta acggaaggtt caacatttta tgcccagggc ggtattgccg ccgtgtttga
    10621 tgaaactgac agcattgact cgcatgtgga agacacattg attgccgggg ctggtatttg
    10681 cgatcgccat gcagttgaat ttgtcgccag caatgcacga tcctgtgtgc aatggttaat
    10741 tgaccaaggg gttttgtttg atacccacgt tcaaccgaat ggcgaagaaa gctaccatct
    10801 gacccgtgaa ggtggacata gtcaccgtcg tattcttcat gccgccgacg ccaccggtag
    10861 agaagtacaa tccacgctgg tgagcaaggc gcagaaccat ccgaatattc gtgtgctgga
    10921 gcgcagcaac gcggttgatc tgattgtctc tgacaaaatt ggcctgccgg gcacgcgacg
    10981 ggttgtaggc gcgtgggtat ggaaccgaaa taaagaaacg gtggaaacct gccacgcaaa
    11041 agcagtggta ctggcaaccg gcggtgcgtc gaaggtgtat cagtacacca ccaatccgga
    11101 tatttcttct ggcgatggca ttgctatggc gtggcgcgcg ggctgtcggg ttgccaatct
    11161 cgaatttaat cagttccacc ctaccgcact gtatcaccca caggcacgca atttcctgtt
    11221 aacggaagca ctgcgcggcg aaggcgctta tctcaagcgc ccggatggca cgcgttttat
    11281 gcccgatttt gatgagcgcg gcgaactggc cccgcgcgat attgtcgccc gcgccattga
    11341 ccatgaaatg aaacgcctcg gcgcagattg tatgttcctc gacatcagcc ataagcccgc
    11401 cgattttatt cgccagcatt tcccgatgat ttatgaaaaa ttgctcgggc tggggattga
    11461 tctcacacaa gaaccgatac cgattgtgcc tgctgcacac tatacctgcg gtggtgtaat
    11521 ggttgatgat catgggcgta cggacgtcga gggcttgtat gccattggcg aggtgagtta
    11581 taccggctta cacggcgcta accgcatggc ctcgaattca ttgctggagt gtctggtcta
    11641 tggctggtcg gcggcagaag atatcaccag acgtatgcct tatgcccacg gcgtcagtac
    11701 gttaccgccg tgggatgaaa gccgcgttga gaaccctgac gaacgggtag taattcagca
    11761 taactggcac gagctacggc tgtttatgtg ggattacgtt ggcattgtgc gcacaacgaa
    11821 gcgcctggaa cgcgccctgc ggcggataac catgctccaa caagaaatag acgaatatta
    11881 cgcccatttc cgcgtctcaa ataatttgct ggagctgcgt aatctggtgc aggttgcgga
    11941 attgattgtt cgctgtgcga tgatgcgcaa ggagagtcgt ggcctgcatt tcacgctgga
    12001 ttatccggaa ctgctcaccc attccggtcc gtcgatcctt tcccccggca atcattacat
    12061 aaacagataa aaagcctggg tcagcgccgt atacgcttcg gaatagttct ggtctggccc
    12121 acgaatgact aagcgatcgc taaagcattc tcccgcctgc ggggagaatg ccagcagcac
    12181 ccgatgcggc agtcgcgctt cgttttccgc cacatccgtc cgcaaacgta aatgccagcc
    12241 catgcttaat gccagctccg taaaaccatt accaatctgc tctggcagca ctacgcagaa
    12301 aaatccctct tcggtaatgc actccgccgc acaggtcagc agcgatgggt gatcaagcgt
    12361 agtggtatag cgagcctgtt cccgttgagg ggtcgcgcac tctactccct gctgatagta
    12421 aggtgggtta ctgatgatta aatcgaagcg tactgtctgc tgtgtgatcc actgctgaat
    12481 atccgccgta tggacgttaa tccgctctgc ccacggggac tggttgatat tttcctgcgc
    12541 ctgcgcggca gcttcacttt ccagctcaac ggcatcaatt atcacgctgt catcggttcg
    12601 ctgcgccagc attaatgcca gcaacccgct acccgcgccg atatcaaggc aacgtttcac
    12661 cccagccacc ggtgcccatg cgcccagcaa aatgccatcc gttcccactt tcatcgcaca
    12721 gcgatcgtga gcaacaaaaa actgtttaaa agtaaatcca ttacgacgaa gcacggatgt
    12781 agactgtgac atgaaaataa aaccttgcag gaaaaacggc gatagcaccg ggtgagaaca
    12841 atacccgaga agcgatatcc atacaaacag atgaagattg cagccgtaac gtctataatc
    12901 agcgccccac acagaggtag aacatgactg taacgacttt ttccgaactt gaactcgacg
    12961 aaagcctgct ggaagccctc caggataaag gtttcactcg cccgaccgcc attcaggctg
    13021 ccgccattcc gcctgcgctc gatggccgtg atgtactcgg ttctgcgccg acaggcaccg
    13081 gtaaaacggc ggcgtatctg ctgccagcgt tgcagcacct gctcgatttc ccgcgtaaga
    13141 aatccggtcc gccgcgtatt ttgatcctca ccccaactcg cgagctggcg atgcaggtgg
    13201 ccgatcatgc ccgcgaactg gcgaaacata cgcatctgga tatcgccacc atcaccggcg
    13261 gcgtagccta tatgaaccac gcggaagtgt tcagcgaaaa tcaggacatc gtggtcgcca
    13321 cgaccggacg tctgctgcaa tacataaaag aagagaactt cgattgccgc gcggttgaaa
    13381 cgctgatcct cgacgaagca gaccgtatgc tggatatggg ctttgctcag gatatcgaac
    13441 atattgctgg cgaaactcgc tggcgtaaac agaccctgct cttttcggca acgctggaag
    13501 gcgatgcgat tcaggacttt gccgagcgtc tgctggagga tccggtggaa gtttctgcga
    13561 atccgtccac ccgtgagcgc aaaaaaattc atcagtggta ttaccgcgcc gatgatcttg
    13621 agcataaaac cgcgttgctg gtgcatctgt taaaacagcc tgaagcgacc cgctcaattg
    13681 tgtttgtgcg taagcgtgaa cgtgtgcatg agctggcaaa ctggctgcgc gaagcgggca
    13741 tcaacaactg ctatctcgaa ggtgagatgg tacaaggcaa gcgtaacgaa gcgatcaagc
    13801 gtttgaccga aggtcgcgta aacgtactgg ttgcaaccga tgttgccgcg cgcggtatcg
    13861 acattcctga cgtcagccac gtctttaact tcgatatgcc gcgcagtggc gatacttatt
    13921 tgcaccgtat cggacgtacc gcgcgcgccg gtcgtaaagg caccgcgatt tcgctggtgg
    13981 aagcccatga ccatttgctg ctgggcaaag ttggccgtta tattgaagag ccaattaaag
    14041 ctcgcgttat tgatgagtta cgcccgaaaa cgcgtgcgcc aagcgagaag cagaccggca
    14101 agccatcgaa gaaagtactg gcaaaacgcg ccgagaagaa aaaagttaaa gagaaagaga
    14161 agccgcgagt gaaaaaacgc catcgcgata ccaaaaatat tggtaagcgc cgtaaaccaa
    14221 gcggaacggg cgtgccaccg caaacgacag aagagtaatc tcaatgccgg gtttaagccc
    14281 ggcattattt ttatccagcc acaaaacact cttcaacaca ctgaataaaa gtgtgcatcg
    14341 ccggactaac cgcttttccg gcatggtgag cgcacattgc cgtaatggtc tgcgtctgtt
    14401 cgccaaaagg caattcgatt aattcgccac tcgcaagttc atttcccact gcaaagcgcg
    14461 gcaggtaact gaccccgata tttgccgcga cacaacgctt gatgctttcg atacttataa
    14521 gctcaatggt gttttccacc gtgatccgcc gctggcgcag cgtgctctca aatatctgcc
    14581 ggaagacaca ttgtggttcg ttgataataa agctacaggc gttatgtctt cccggctcag
    14641 taaaatcgat atctgcaatt tgcggtgaag ccaccagcac cagcggttgt tcacccaact
    14701 ctcgtcggtt cagaacatca tcattcccta cgcgataaaa aaccccgaca tcggcctcat
    14761 cattcagtag cgcatcacgg atcacgtaac agttcagcga ctgcaacgat aaacgcactt
    14821 ttggagcgcg ttgccgaaaa cgctgcaaca cctgcggcat tcggtaagag agcaacgttt
    14881 cgcctgaaac aacgcgtagt tccccgtccg gatccgactc ttttttcgca gcctcacgaa
    14941 gcgtatccat cactcgggta agttcataga tgtgcggcag caactttttt ccttcgcggg
    15001 taaggcacat tcgtcgacca attttctcaa acaattgtac cgagaactcc tgctcaagct
    15061 gctgaatatg aaaagtcacc gtcgattgtg tacagcacaa tttttgcgaa gctcgcaaaa
    15121 aggaaccctc ttccaccacg gttttaagtg taataaaacg gcgcagatcc ataaccccaa
    15181 acctatcgaa aatatcgaat ttagaatgta aaaacattca tttttttaaa tgttccgtgt
    15241 cgggtactgt ctaccaaaac agaggagata acaagtgaca ccgacccttt taagtgcttt
    15301 ttggacttac accctgatta ccgccatgac gccaggaccg aacaatattc tcgcccttag
    15361 ctctgctacg tcgcatggat ttcgtcaaag tacccgcgtg ctggcaggga tgagtctggg
    15421 atttttgatt gtgatgttac tgtgtgcggg catttcattt tcactggcag tgattgaccc
    15481 ggcagcggta caccttttga gttgggcggg ggcggcatat attgtctggc tggcgtggaa
    15541 aatcgccacc agcccaacaa aggaagacgg acttcaggca aaaccaatca gcttttgggc
    15601 cagctttgct ttgcagtttg tgaacgtcaa aatcattttg tacggtgtta cggcactgtc
    15661 gacgtttgtt ctgccgcaaa cacaggcgct aagctgggta gttggcgtca gcgttttgct
    15721 ggcgatgatt gggacgtttg gtaatgtgtg ctgggcgctg gcggggcatc tgtttcagcg
    15781 attgtttcgc cagtatggtc gccagttaaa tatcgtgctc gcgctgctgc tgatctattg
    15841 cgcggtacgc attttctatt aattaaaaaa gcggaagagg tcgccctctt ccgcttagta
    15901 acttgctact taagccttac aggctttcag taaaggtacg agcgataacg tcgcgctgct
    15961 gttccggagt cagagagtta aagcgaactg cataacctga tacacggatg gtcagctgcg
    16021 gatatttttc cggatgctta actgcatctt ccagagtttc acgacgcaga acgttaacgt
    16081 tcaggtgttg accaccttca acgcgaactt ctggtttcac ttctactgga acttcacggt
    16141 attcaatgtc acccagtttg cttactgcaa ccacttcatc ttctgcataa cctgcttttg
    16201 caacgatgca acgcgcttcg cctttttcgc tgtccagcag ccagaaagag ttcagcagat
    16261 cgtcgttagc ggctttagta atctggatac ctgtaatcat gtgatgcctc cccggcaaaa
    16321 ttatttgatt tattcagcct gtcgcggcca attggtaaaa ccattgttgc ttgagtgtat
    16381 atatactcct caacaaccct tgattccttg atttaaatca ataaaaacca cacatcgatt
    16441 gtggtcgcaa atggatttta ttgttttaca tcaacttatg cgggtgtgaa attttaccaa
    16501 tttacatttt tttgcactcg tttaagtcta aaaaatgagc atgattttgt tctgtagaaa
    16561 taagcagtta agctaggcgg attgaagatt cgcaggagag cgagatggct aacgaattaa
    16621 cctggcatga cgtgctggct gaagagaagc agcaacccta ttttcttaat acccttcaga
    16681 ccgtcgccag cgagcggcag tccggcgtca ctatctatcc accacaaaaa gatgtcttta
    16741 acgcgttccg ctttaccgag ttgggtgacg ttaaagtggt gattctcggc caggatcctt
    16801 atcacggacc gggacaggcg catgggctgg cattttccgt tcgccccgga atcgccactc
    16861 ctccgtcact gctgaatatg tataaagagc tggaaaatac tattccgggc ttcacccgcc
    16921 ctaatcatgg ctatctcgaa agctgggcgc gtcagggcgt tctgctgctc aatactgtgt
    16981 tgacggttcg cgcaggtcag gcgcattccc acgccagcct cggttgggag acgtttactg
    17041 ataaagtcat cagcctgatt aaccagcacc gcgaaggcgt ggtgtttttg ttgtggggat
    17101 cacatgcgca aaagaaaggg gcgattatag ataagcaacg ccatcatgta ctgaaagcac
    17161 cgcatccgtc gccgctttcg gcgcatcgtg gattctttgg ctgcaaccat tttgtgctgg
    17221 caaatcagtg gctggaacaa cgtggcgaga cgccgattga ctggatgcca gtattaccgg
    17281 cagagagtga gtaaatttgc ggggaaatgc cggatggcag agttgccacc cggctgattt
    17341 atcaggcttt attctgacgc caccattcac caagcaaaac gccggttgcg acagagatat
    17401 tcagcccggc aacgttgccc gtaccgtcaa tcttcacgcg cagatcgttc ggatcgcgtg
    17461 cggcatccgg taacccttca tattcctgac ccagcaccag taccattttc gctggcagac
    17521 tggttttgaa cagcggttta ccctgctcgc tggaagtggt cactacggtg taacctgcct
    17581 gacggaaatc atccagcacg ttaacaatgt tgtcgccagt aatcggctga acgtgctctg
    17641 cgccgccttc tgcggtacgg atagccgccc ccgactccag cagtgccgca tcctgcacca
    17701 caacgccttt cacgccgaag tgcgcgcagc tgcgcatcat gccacccagg ttatgcgggt
    17761 tagattcgtt ttccagcgcc agtacacaat cctgcgcgcc tgcctggctt acccactgct
    17821 gcacggttgt accgttacgc tttttgatca agaagcaaac gccgccgtga tgttccgtgc
    17881 ctgacgcttt tgtcaattcc gcttcatcca ccacatggta cgctttgcgg tttgccgcca
    17941 tccagcgcaa ggcttcttta aaacgtggcg ttacgctctg gataaaccag gcgcgaacaa
    18001 tcgcttccgg acggctctgg aacagtgcct gacatgcatt ttcgccgtag acgcgggttt
    18061 cttccgcacg ctgacgacgc aaaacttctg gatcaatata acttttacca ctgatgccac
    18121 cgtgatcggc cttttccggc gtctcatcac ccggcgcgcg ggaaaccgtg cgccacggcg
    18181 aatcttccca cttgcggtca cggggctgac tctgtttgtc atcgcgggcg gggcgacggc
    18241 caccgtcagc acgagatttt cctggacgcc cgcccccttt cccggtacgc gggttgtggg
    18301 tacgtttatc agaatcatca tcactgcgga catacatcac tttgaccttg ccgcttttac
    18361 ctttcatttc atcgttcatg cttttctcca ccagcgctgc gcgaagcgcg cagattaccc
    18421 gaagtccgcg cggttcgcca tgatttcgta ccaaagcctg cgactatcat acctattgaa
    18481 taaaacagat tgttgtctgg aacaatgtcc ccgataatat gtaacatatt agaaacatac
    18541 cggcgtcgtt gccgataagt ctccttactc atcccgaggt tagttatgaa taccgtttgt
    18601 acccattgtc aggccatcaa tcgcattccc gacgatcgga tcgaagatgc ggcaaaatgc
    18661 ggacgctgcg gtcacgactt gtttgacgga gaggtgatta atgcgaccgg tgaaacactc
    18721 gacaaattgc tgaaggatga tctacctgtg gtgatcgact tctgggcacc gtggtgcggc
    18781 ccctgccgta atttcgcacc aatttttgaa gatgtcgcgc aagagcgtag cggtaaagtg
    18841 cgctttgtga aagtgaatac cgaagctgaa cgtgaattga gcagtcgctt tggaattcgt
    18901 agtataccga cgatcatgat tttcaaaaac ggtcaggttg tcgacatgct taatggcgca
    18961 gtaccgaaag cgccgttcga cagctggctg aacgaatctc tttaatctta ccggggcgca
    19021 tcttgtgccc cgttttctcc tctgcgacaa tggcgttttt tcgacgctct cttatgaccg
    19081 aaaacgctgt tctccagtta cgcgccgagc gtattgcgcg cgcaacacgt ccttttcttg
    19141 cccgcggtaa tcgcgttcgt cgctgccaac gctgtctttt gccagagaaa ttatgtctct
    19201 gttcgacaat taccccagca caagcaaaaa gtcgcttctg tttgctgatg ttcgacaccg
    19261 agccaatgaa gcccagtaat accgggcgtc tgattgctga tattttgcct gataccgttg
    19321 cgtttcaatg gtcgcgtacc gaaccctcgc aggatttgct ggatctggta caaaacccgg
    19381 actatcaacc aatggtggtc tttcccgcct cgtatgctga tgagcaacgg gaagtgatct
    19441 tcacaccacc tgccggtaag ccaccgctgt ttatcatgct cgatggtacc tggccggaag
    19501 ctcgcaagat gtttcgtaaa agtccgtatc tggataatct tcccgtcatt tccgtcgatc
    19561 tttcccggct ttctgcctat cgcctgcgtg aagcccaggc tgaaggccaa tattgtactg
    19621 ccgaggtagc catcgcactg ttagatatgg ccggcgatac cggggcggcg gcagggttag
    19681 gcgagcattt tacccgcttt aaaacacgct atctggcagg aaaaacgcaa catctgggta
    19741 gcatcacagc agaacagtta gaaagcgttt aaaatcattc ggtcacttct gcgggagacc
    19801 ggtatgagtc agcgaggact ggaagcacta ctgcgaccaa aatcgattgc ggtaattggc
    19861 gcatcgatga aacccaatcg cgcaggttac ctgatgatgc gtaacctgct ggcgggaggc
    19921 tttaacggac cggtactccc ggtgacgcca gcctggaaag cggtgttggg tgtgttggcc
    19981 tggccggata ttgccagctt gccctttaca cccgaccttg cggttttatg tactaatgcc
    20041 agccgtaatc ttgctcttct ggaagagctc ggcgagaaag gctgtaaaac ctgcattatt
    20101 ctttccgccc cggcatcgca acacgaagat ctccgcgcct gcgccctgcg ccataacatg
    20161 cgcctgctag gaccaaacag tctgggttta ctggctccct ggcaaggtct gaatgccagc
    20221 ttttcgcctg tgccgattaa acgcggcaag ctggcgttta tttcacaatc ggctgccgtc
    20281 tccaacacca tcctcgactg ggcgcaacag cgtgagatgg gcttttccta ctttattgcg
    20341 ctcggcgaca gcctggatat cgacgttgat gaattgcttg actatctggc acgcgacagt
    20401 aaaaccagcg ccatcctgct ctatctcgaa cagttaagcg acgcgcgacg ctttgtttcg
    20461 gcggcccgta gtgcctctcg caacaaaccg attctggtga ttaaaagcgg acgtagcccg
    20521 gcggctcaac gtctgttgaa caccacggca ggaatggatc cggcgtggga tgcggctatt
    20581 cagcgtgccg gtttgttgcg ggtacaggac acccacgaac tgttttcggc ggtggaaacc
    20641 cttagccata tgcgcccgct gcgtggcgac cggttgatga ttatcagcaa cggtgctgcg
    20701 cctgccgcgc tggcgcttga tgccttatgg tcacgcaatg gcaagctggc aacactaagc
    20761 gaagaaacct gccagaaact gcgcgatgca ctgccaggac atgtggcaat ctctaacccg
    20821 ctcgatctgc gcgatgacgc cagcagtgag cactatatta aaacgctgga cattctgctc
    20881 cacagccagg attttgatgc gctgatggtt attcattcgc ccagcgccgc tgctcccgca
    20941 acagaaagcg cgcaagtatt aattgaagcg gtaaagcatc atccccgcag caagtatgtt
    21001 tctctgctga cgaactggtg tggcgaacat tcctcgcaag aggcacgacg attattcagc
    21061 gaagccgggc tgccgaccta ccgtaccccg gaaggaacca tcactgcttt tatgcatatg
    21121 gtggagtacc ggcgtaatca gaagcaacta cgcgaaacgc cggcgttgcc cagcaatctg
    21181 acctccaata ccgcagaagc gcatcttctg ttgcaacagg cgattgccga aggagcaacg
    21241 tcactcgata cccatgaagt tcagcctatc ctgcaagcat atggcatgaa cacgctcccc
    21301 acctggattg ccagcgatag caccgaagcg gtgcatattg ccgaacagat tggttatccg
    21361 gtggcgctga aattgcgttc gccggatatt ccacataaat cggaagttca gggcgtcatg
    21421 ctgtacctgc gtacagccaa tgaagtccag caagcggcaa acgccatttt cgatcgcgta
    21481 aaaatggcct ggccgcaggc acgggtccac ggcctgttgg tgcaaagtat ggctaaccgt
    21541 gctggtgctc aggagttgcg ggttgtggtt gagcacgatc cggttttcgg gccgttgatc
    21601 atgctgggcg aaggcggtgt ggagtggcgt cctgaagatc aagccgtcgt cgcgttaccg
    21661 ccgctgaaca tgaacctggc ccgctatctg gttattcagg ggatcaaaag taaaaagatt
    21721 cgtgcacgca gtgcgctacg cccattggat gttgcaggct tgagccagct tctggtgcag
    21781 gtttccaact tgattgtcga ttgcccggaa attcagcgtc tggatattca tcctttgctg
    21841 gcttctggca gtgaatttac cgcgctggat gtcacgctgg atatctcgcc gtttgaaggc
    21901 gataacgaga gtcggctggc agtgcgccct tatccgcatc agctggaaga atgggtagaa
    21961 ttgaaaaacg gtgaacgctg cttgttccgc ccgattttgc cagaagatga gccacaactt
    22021 cagcaattca tttcgcgagt caccaaagaa gatctttatt accgctactt tagcgagatc
    22081 aacgaattta ctcatgaaga tttagccaac atgacgcaga tcgactacga tcgggaaatg
    22141 gcgtttgtag cggtacgacg tattgatcaa acggaagaga tcctcggcgt cacgcgtgcg
    22201 atctccgacc ctgataacat cgatgccgaa tttgctgtgc tggttcgctc ggatctcaaa
    22261 gggttaggct taggtcgacg cttaatggaa aagttgatta cctatacgcg agatcacgga
    22321 ctacaacgtc tgaatggtat tacgatgcca aacaatcgtg gcatggtggc gctagcccgc
    22381 aagctcgggt ttaacgttga tatccagctc gaagagggga tcgttgggct tacgctaaat
    22441 cttgcccaac gcgaggaatc atgagtaagg tactggaaat gttgaccact taatcgggac
    22501 tggtgttatt attgcccgct tatgtcgtct gcattgcaca gaggaccctt caatgaacag
    22561 agaagaaatg cactgtgatg ttgtcaaaat ttaagcgtaa taaacatcaa caacaccttg
    22621 cccaactacc caagatttct caatcagttg atgatgtcga tttcttttac gctcccgccg
    22681 acttccggga gacgctgctg gaaaaaatag ccagcgcgaa gcagcgcatt tgcattgtcg
    22741 ccctgtatct cgaacaggat gacggtggca aaggcattct gaacgcgttg tatgaagcta
    22801 aaaggcagcg tccggaactg gatgtgcggg tgctggtcga ctggcatcgt gcacaacgtg
    22861 gacgcattgg cgctgcggca tctaacacta acgctgactg gtactgccgc atggcgcagg
    22921 aaaatccggg cgtagatgtt ccggtttatg gcgttccaat caatacccgt gaagcccttg
    22981 gtgttctgca ctttaaaggc tttatcatcg acgatagcgt actttatagc ggtgccagcc
    23041 tgaacgatgt ttacctgcat cagcacgata aatatcgcta cgaccgttat catctgatcc
    23101 gtaaccgtaa gatgtcagac attatgtttg aatgggttac acagaatatt atgaatggcc
    23161 gcggcgttaa tcgtctggat gatgttaatc ggccaaaaag cccggaaatc aagaacgata
    23221 ttcgtctgtt ccgccaggag ctgcgtgatg ccgcttatca tttccagggc gatgccgaca
    23281 acgatcagct ttccgtaacg ccgctagtgg ggctggggaa atcgagtctg ttgaacaaga
    23341 ccattttcca tcttatgcct tgtgccgagc agaaactaac catctgtacg ccatacttca
    23401 acctgccagc aatccttgtg cgcaatatta tccagttgct gcgcgaaggg aaaaaggtcg
    23461 aaattattgt tggtgataaa accgcgaacg acttctacat tccggaagat gaacctttca
    23521 agataattgg cgcattgcct tatctctatg agatcaatct gcgtcgtttc ctgagccgtt
    23581 tgcagtatta cgtcaatact gaccagctag tggttcggtt atggaaagat gacgacaaca
    23641 cctatcacct aaaagggatg tgggttgatg ataagtggat gttgatcacc ggtaataacc
    23701 tgaacccgcg cgcctggcgt ctggatctgg aaaacgccat tttgatccac gatccacaac
    23761 tggagcttgc gccgcagcga gagaaagaac tggagctgat ccgcgagcat accaccatcg
    23821 ttaagcacta tcgcgatctg caaagtattg ccgattatcc ggtgaaggtt cgtaaactca
    23881 tccgccgttt gcgccgtatc cgcatcgacc gattaattag ccgcatcctg taatcacaac
    23941 cccgtcctgt acggggtttg ttttttggag gccacgtttt gcgtattctt tttgtctgtt
    24001 cgctattgtt actttctgga tgcagccata tggctaacga tagctggagc gggcaggata
    24061 aagctcaaca ctttattgcc tcggcgatgc tttccgccgc cggaaatgaa tattcacagc
    24121 atcaggggat gagccgggat cgcagtgcca tgtttggatt gatgttctct gtcagtttgg
    24181 gggcgtcaaa agagctttgg gatagccgcc ccgaagggag cggctggagc tggaaggatt
    24241 tggcctggga tgtcgccggt gcaagcaccg gctataccgt ctggcaactg acccgtcact
    24301 aaagacgcat ccccttccct ttgcgatgta gcatcaaaga aaccagaaac gccaccacgg
    24361 ccatcaaggt cacataccag aagaaggctg tttccattcc tattgatttc agcgacaacg
    24421 ctacgtactc cgccgaacca ccaaatatag cattagcgac cgcatatgac aggccaacgc
    24481 ctaatgcgcg aacctgtgcc gggaacatct cagccttcag tattccactg attgatgtat
    24541 aaaaactcac tatcagcagg gcacacatca ccagaccaaa agcggcataa ggcgaggaaa
    24601 cgttttgcaa tgctgagaga ataggaacgg taaaaatggc tgccagcgaa ccgaaacata
    24661 acattgaggt acggcgacca atcttatccg acagcgcgcc aatgagtggt tgaataagca
    24721 tgaatacaaa caatgcggca gtcataatgc cactcgccac gttggcatgc attcccgcag
    24781 tatttaccag atacttctgc atataagtgg tgaaggtata gaaacaaagg gagcccgcag
    24841 cggtaaaacc gagaaccatg atgaatgcac ggcgattgcg ccataatcct ttcagagatc
    24901 cagcttcttt taaagcgcgc gtttcttgtt gcgaagtttc atctaactga cgacgtaacc
    24961 acaacgccac aacagctaac acagctccta acgcgaaagg aatacgccat ccccactctc
    25021 tgagtgcagc gtcttccatg gtgtgttgta aaaccacgac aaccagtagg gctagcagtt
    25081 gtccgccgat caacgtcaca tactgaaatg atgcgtaaaa acctttgcgc ccttcaacgg
    25141 caacttcact catataggtg gcgctggtgc catattctcc gccaacagat aatccctgaa
    25201 ataaacgcgc gagaagcaat aatgccggag cccacgtacc tatagtttca taacctggga
    25261 ggcaggcgat aaccagcgat ccgaaacaca tcatacacac cgataacagc atcgattttt
    25321 tgcgaccatg tttatcggct atgcggccaa atagccaacc gcctattggg cgcatcagga
    25381 atcccgcagc aaaaacacct gctgtttgta gtagttgagt cgtcgtgttc ccggaaggga
    25441 agaaaatgtg ggcgaagtag agtgaacaga acgagtagac atagaaatcg aaccactcga
    25501 ccagattacc tgaagaggcc cccacaatcg cccaaatgcg gcgacgagta tcactacttg
    25561 tcagtttgct gtctgccgtt acagtacttt cagccatgcc attatgtctc ctgccgtaat
    25621 ccgatgcttt tgttggtcgc ttttgtttat ttcttttggt aaagaaaatg ttatacattt
    25681 gttgcgtatc attatgcaac cttaaccatg aatttagtta gcaggaaaat ggttattgag
    25741 gagcttaagg ataaatttct ggtaaggagg acacgtatgg aagtaggcaa gttggggaaa
    25801 ccgcatccgt tgctgaatct ggcatatgtg ggagtataag acgcgcagcg tcgcatcagg
    25861 catttttttc tgcgccaatg caaaaaggcc atcctgacgg atggcctttc gcttaatttg
    25921 atgcctggca gttccctact ctcgcatggg gagaccccac actaccatcg gcgctacggc
    25981 gtttcacttc tgagttcggc atggggtcag gtgggaccac cgcgctaagg ccgccaggca
    26041 aattctgttt tatcagaccg cttctgcgtt ctgatttaat ctgtatcagg ctgaaaatct
    26101 ttctctcatc cgccaaaaca
//
LOCUS       DAPOAV010000063        25912 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.063, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000063 DAPOAV010000000
VERSION     DAPOAV010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25912
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.063"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(329..1465)
                     /locus_tag="RN951_002961"
     CDS             complement(329..1465)
                     /locus_tag="RN951_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HDX2527932.1"
                     /translation="MDLLIVLTYVALAWAVFKIFRIPVNQWTLATAALGGVFLVSGLI
                     LLMNYNHPYTFTAQKAVIAIPITPQVTGIVTEVTDKNNQLIQKGEVLFKLDPVRYQAR
                     VDRLQADLMTATHNIKTLRAQLTEAQANTTQVSAERDRLFKNYQRYLKGSQAAVNPFS
                     ERDIDDARQNFLAQDALVKGSVAEQAQIQSQLDSMVNGEQSQIVSLRAQLTEAKYNLE
                     QTVIRAPSNGYVTQVLIRPGTYAAALPLRPVMVFIPEQKRQIVAQFRQNSLLRLKPGD
                     DAEVVFNALPGQVFHGKLTSILPVVPGGSYQAQGVLQSLTVVPGTDGVLGTIELDPND
                     DIDALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWMHYLYLDH"
     gene            complement(1468..1830)
                     /locus_tag="RN951_002962"
     CDS             complement(1468..1830)
                     /locus_tag="RN951_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3302 domain-containing protein"
                     /protein_id="HDX2527933.1"
                     /translation="MFLNYFALGVLIFVFLVIFYGIIAIHDIPYLIAKKRNHPHADAI
                     HTAGWVSLFTLHVIWPFLWIWATLYQPERGWGMQSHVASQEKATDPEIAALSDRISRL
                     EHQLAAEKKTDYSTFPEI"
     gene            2367..4280
                     /gene="mtlA"
                     /locus_tag="RN951_002963"
     CDS             2367..4280
                     /gene="mtlA"
                     /locus_tag="RN951_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HDX2527934.1"
                     /translation="MSSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLP
                     NETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVVGAITTMGVIVGADMPMFLGSMI
                     AGPLGGWCIKHFDRWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPIVEALSKM
                     LAAGVNFMVVHDMLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIE
                     ANPGPGMGVLLAYMFFGRGSAKQSAGGAAIIHFLGGIHEIYFPYVLMNPRLILAVILG
                     GMTGVFTLTILGGGLVSPASPGSILAVLAMTPKGAYFANIAGVCAAMAVSFVVSAILL
                     KTSKVKEEDDIEAATRRMQDMKAESKGASPLSAGDVTNDLSHVRKIIVACDAGMGSSA
                     MGAGVLRKKIQDAGLSQISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLT
                     NFLDSGLYTSLTERLVAAQRHTANEEKVKDSLKDSFDDSSANLFKLGAENIFLGRKAA
                     TKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTPTYLGESIAVPHGTVEAKDRVLKT
                     GVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTT
                     SVDEVLELLAGRK"
     gene            4510..5658
                     /gene="mtlD"
                     /locus_tag="RN951_002964"
     CDS             4510..5658
                     /gene="mtlD"
                     /locus_tag="RN951_002964"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDX2527935.1"
                     /translation="MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARH
                     SYQVHVVGETEQVDTVSGVNAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKG
                     LVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRI
                     VPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNT
                     GHAITAYLGKLAGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQK
                     ILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYGLPHKNLIEGIAAAMHF
                     RSEDDPQAQELAALIADKGPQAALAQISGLDANSEVVSEAVTAYKAMQ"
     gene            5658..6245
                     /gene="mtlR"
                     /locus_tag="RN951_002965"
     CDS             5658..6245
                     /gene="mtlR"
                     /locus_tag="RN951_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol operon repressor MtlR"
                     /protein_id="HDX2527936.1"
                     /translation="MVDQAQDTLRPNNRLSDMQATMEQTQAFENRVLERLNAGKTVRS
                     FLITAVELLTEAVNLLVLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLKLIYGLGVI
                     NRQEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVAALPPPPQFEPADSSL
                     YAMQIQRYQQAVRSTMVLSLTELISKISLKKAFQK"
     gene            complement(6257..6466)
                     /locus_tag="RN951_002966"
     CDS             complement(6257..6466)
                     /locus_tag="RN951_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527937.1"
                     /translation="MGKLGENVPLLIDKAVDFMASSQAFREYLKKLPPRNAIPSGIPD
                     ESVPLYLQRLEYYRRLYRPKQVEGQ"
     gene            6751..7113
                     /locus_tag="RN951_002967"
     CDS             6751..7113
                     /locus_tag="RN951_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibL family ribosome-associated protein"
                     /protein_id="HDX2527938.1"
                     /translation="MKEVEKNEIKRLSDRLDAIRHQQADLSLVEAADKYAELEKEKAT
                     LEAEIARLREVHSQKLSKEAQKLMKMPFQRAITKKEQADMGKLKKSVRGLVVVHPMTA
                     LGREMGLQEMTGFSKTAF"
     gene            7485..9140
                     /gene="lldP"
                     /locus_tag="RN951_002968"
     CDS             7485..9140
                     /gene="lldP"
                     /locus_tag="RN951_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
                     /protein_id="HDX2527939.1"
                     /translation="MNLWQQNYDPAGNIWLSSLIASLPILFFFFALIKLKLKGYVAAS
                     WTVAIALAVALLFYKMPVANALASVVYGFFYGLWPIAWIIIAAVFVYKISVKTGQFDI
                     IRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLC
                     LIVNTAPVAFGAMGIPILVAGQVTGIDSFEIGQMVGRQLPFMTIIVLFWIMAIMDGWR
                     GIKETWPAVVVAGGSFAIAQYLSSNFIGPELPDIISSLVSLLCLTLFLKRWQPVRVFR
                     FGDLGASQVDMTLAHTGYTAGQVLRAWTPFLFLTATVTLWSIPPFKALFASGGALYEW
                     VINIPVPYLDKLVARMPPVVSEATAYAAVFKFDWFSATGTAILFAALLSIVWLKMKPS
                     DAISTFGSTLKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGHAFTFFSPFLG
                     WLGVFLTGSDTSSNALFAALQATAAQQIGVSDLLLVAANTTGGVTGKMISPQSIAIAC
                     AAVGLVGKESDLFRFTVKHSLIFTCIVGVITTLQAYVLTWMIP"
     gene            9140..9916
                     /gene="lldR"
                     /locus_tag="RN951_002969"
     CDS             9140..9916
                     /gene="lldR"
                     /locus_tag="RN951_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LldR"
                     /protein_id="HDX2527940.1"
                     /translation="MIVLPRRLSDEVADRVRALIDEKNLEAGMKLPAERQLAMQLGVS
                     RNSLREALAKLVSEGVLLSRRGGGTFIRWRHDTWSEQNIVQPLKTLMTDDPDYSFDIL
                     EARYAIEASTAWHAAMRATPGDKEKIQLCFEATLSEDPDIASQADVRFHLAIAEASHN
                     IVLLQTMRGFFDVLQSSVKHSRQRMYLVPPVFSQLTEQHQAVIDAIFAGDADGARKAM
                     MAHLSFVHTTMKRFDEDQARHARITRLPGEHNEHSREKNA"
     gene            9913..11103
                     /gene="lldD"
                     /locus_tag="RN951_002970"
     CDS             9913..11103
                     /gene="lldD"
                     /locus_tag="RN951_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent L-lactate dehydrogenase"
                     /protein_id="HDX2527941.1"
                     /translation="MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSE
                     VALRQRILKNMSDLSLETTLFNEKLSMPVALAPVGLCGMYARRGEVQAAKAADAHGIP
                     FTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPT
                     PGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLE
                     DYIGWLGNNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHG
                     GRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAFLY
                     ALATAGQAGVANLLNLIEKEMKVAMTLTGAKSISEITQDSLVQGLGKELPAALAPMAK
                     GNAA"
     gene            11301..11774
                     /gene="trmL"
                     /locus_tag="RN951_002971"
     CDS             11301..11774
                     /gene="trmL"
                     /locus_tag="RN951_002971"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HDX2527942.1"
                     /translation="MLNIVLYEPEIPPNTGNIIRLCANTGFRLHIIEPMGFAWDDKRL
                     RRAGLDYHEFTAVTRHHDYRAFLEAENPQRLFALTTKGTPAHSAVSYQDGDYLMFGPE
                     TRGLPASILDALPAEQKIRIPMVPDSRSMNLSNAVSVVVYEAWRQLGYPGAVLRD"
     gene            complement(11827..12648)
                     /gene="cysE"
                     /locus_tag="RN951_002972"
     CDS             complement(11827..12648)
                     /gene="cysE"
                     /locus_tag="RN951_002972"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HDX2527943.1"
                     /translation="MSCEELEIVWNNIKAEARTLADCEPMLASFYHATLLKHENLGSA
                     LSYMLANKLSSPIMPAIAIREVVEEAYAADPEMIASAACDIQAVRTRDPAVDKYSTPL
                     LYLKGFHALQAYRIGHWLWNQGRRALAIFLQNQVSVTFQVDIHPAAKIGRGIMLDHAT
                     GIVVGETAVIENDVSILQSVTLGGTGKSGGDRHPKIREGVMIGAGAKILGNIEVGRGA
                     KIGAGSVVLQPVPPHTTAAGVPARIVGKPDSDKPSMDMDQHFNGINHTFEYGDGI"
     gene            complement(12728..13747)
                     /gene="gpsA"
                     /locus_tag="RN951_002973"
     CDS             complement(12728..13747)
                     /gene="gpsA"
                     /locus_tag="RN951_002973"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDX2527944.1"
                     /translation="MNQRNASMTVIGAGSYGTALAITLARNGHEVVLWGHDPEHIATL
                     ERDRCNAAFLPDVPFPDTLHLESDLATALAASRNILVVVPSHVFGEVLRQIKPLMRPD
                     ARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTD
                     QTFADDLQQLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTAL
                     ITRGLAEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSA
                     QEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLGRARKD
                     ERSSH"
     gene            complement(13747..14214)
                     /gene="secB"
                     /locus_tag="RN951_002974"
     CDS             complement(13747..14214)
                     /gene="secB"
                     /locus_tag="RN951_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015369180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HDX2527945.1"
                     /translation="MSEQNNTEMTFQIQRIYTKDISFEAPNAPHVFQKDWQPEVKLDL
                     DTASTQLADDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSIAGIEGTQMAHCLGAYC
                     PNILFPYARECITSMVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA"
     gene            complement(14277..14528)
                     /gene="grxC"
                     /locus_tag="RN951_002975"
     CDS             complement(14277..14528)
                     /gene="grxC"
                     /locus_tag="RN951_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 3"
                     /protein_id="HDX2527946.1"
                     /translation="MANVEIYTKETCPYCHRAKALLSSKGVSFQELPIDGNAAKREEM
                     IKRSGRTTVPQIFIDAQHIGGCDDLYALDARGGLDPLLK"
     gene            complement(14670..15101)
                     /locus_tag="RN951_002976"
     CDS             complement(14670..15101)
                     /locus_tag="RN951_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDX2527947.1"
                     /translation="MQEIMQFVGRHPILSIAWIALLVAVLVTTFKSLTSKVKVITRGE
                     ATRLINKEDAVVVDLRQRDDFRKGHIAGSINLLPSEIKANNVGELEKHKDKPVIVVDG
                     SGMQCQEPANALTKAGFAQVFVLKEGVAGWAGENLPLVRGK"
     gene            15346..16890
                     /gene="gpmM"
                     /locus_tag="RN951_002977"
                     /gene_synonym="pgmI"
     CDS             15346..16890
                     /gene="gpmM"
                     /locus_tag="RN951_002977"
                     /gene_synonym="pgmI"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HDX2527948.1"
                     /translation="MSVSKKPMVLVILDGYGYREEQQDNAIFSAKTPVMDALWANRPH
                     TLIDASGLEVGLPDRQMGNSEVGHVNLGAGRIVYQDLTRLDVEIKDRAFFANPVLTGA
                     VDKAKNAGKAVHIMGLLSAGGVHSHEDHIMAMVELAAERGAEKIYLHAFLDGRDTPPR
                     SAESSLKKFEEKFAALGKGRVASIIGRYYAMDRDNRWDRVEKAYDLLTLAQGEFQADT
                     AVAGLQAAYARDENDEFVKATVIRAEGQPDAAMEDGDALIFMNFRADRAREITRAFVN
                     ADFDGFARKKVVNVDFVMLTEYAADIKTAVAYPPASLVNTFGEWMAKNDKTQLRISET
                     EKYAHVTFFFNGGVEESFKGEDRILINSPKVATYDLQPEMSSAELTEKLVAAIKSGKY
                     DTIICNYPNGDMVGHTGVMEAAVKAVEALDHCVEEVAKAVESVGGQLLITADHGNAEQ
                     MRDPATGQAHTAHTNLPVPLIYVGDKNVKAVAGGKLSDIAPTMLSLMGMEIPQEMTGK
                     PLFIVE"
     gene            16900..18183
                     /gene="envC"
                     /locus_tag="RN951_002978"
     CDS             16900..18183
                     /gene="envC"
                     /locus_tag="RN951_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator EnvC"
                     /protein_id="HDX2527949.1"
                     /translation="MRGKAINTMTRAVKPRRFAIRPIIYASVLSAGVLLCAFSAHADE
                     RDQLKSIQADIAAKERAVRQKQQQRASLLAQLKKQEEAISEATRKLRETQNTLNQLNK
                     QIDEMNASIAKLEQQKAAQERSLAAQLDAAFRQGEHTGIQLILSGEESQRGQRLQAYF
                     GYLNQARQETIAQLKQTREEVAMQRAELEEKQSEQQTLLYEQRAQQAKLTQALNERKK
                     TLAGLESSIQQGQQQLSELRANESRLRNSIARAEAAAKARAEREAREAQAVRDRQKEA
                     TRKGTTYKPTESEKSLMSRTGGLGAPRGQAFWPVRGPTLHRYGEQLQGELRWKGMVIG
                     ASEGTEVKAIADGRVILADWLQGYGLVVVVEHGKGDMSLYGYNQSALVSVGSQVRAGQ
                     PIALVGSSGGQGRPSLYFEIRRQGQAVNPQPWLGR"
     gene            18187..19146
                     /locus_tag="RN951_002979"
     CDS             18187..19146
                     /locus_tag="RN951_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312519.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent polysaccharide deacetylase family
                     protein"
                     /protein_id="HDX2527950.1"
                     /translation="MFPFRRNVLAFAALLALSSPVLAGKLAIVIDDFGYRPHNENQVL
                     AMPSAISVAVLPDSPHAREMATKAHNSGHEVLIHLPMAPLSKQPLEKNTLRPEMSSDE
                     IERIIRSAVNNVPYAVGINNHMGSKMTSNLFGMQKVMQALERYNLYFLDSVTIGNTQA
                     MRAAQGTGVKVIKRKVFLDDSQNEADIRVQFNRAIDLARRNGSTIAIGHPHPSTVRVL
                     QQMVYNLPPDITLVKASSLLNEPQVDTSTPPKNAVPDAPRNPFRGVKLCKPKKPIEPV
                     YANRFFEVLSESISQSTLIVYFQHQWQGWGKQPEAAKFNASAN"
     gene            complement(19133..20167)
                     /gene="waaH"
                     /locus_tag="RN951_002980"
     CDS             complement(19133..20167)
                     /gene="waaH"
                     /locus_tag="RN951_002980"
                     /EC_number="2.4.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate:LPS(HepIII) glycosyltransferase"
                     /protein_id="HDX2527951.1"
                     /translation="MMNSTNKLSVIIPLYNAGDDFRTCMESLITQTWTALEIIIINDG
                     STDNSVEIAKHYAENYPHVRLLHQANAGASVARNRGIEVATGKYVAFVDADDEVYPTM
                     YETLMTMALEDDLDVAQCNADWCFRETGETWQSIPTDRLRSTGVLTGPDWLRMGLSSR
                     RWTHVVWMGVYRRDVIVKNNIKFIAGLHHQDIVWTTEFMFNALRARYTEQSLYKYYLH
                     NTSVSRLHRQGNKNLNYQRHYIKITRLLEKLNRNYADKIMIYPEFHQQITYEALRVCH
                     AVRKEPDILTRQRMIAEIFTSGMYKRLITNVRSVKVGYQALLWSFRLWQWRDKTRSHH
                     RITRSAFNLR"
     gene            complement(20406..21431)
                     /gene="tdh"
                     /locus_tag="RN951_002981"
     CDS             complement(20406..21431)
                     /gene="tdh"
                     /locus_tag="RN951_002981"
                     /EC_number="1.1.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HDX2527952.1"
                     /translation="MKALSKLKAEEGIWMTDVPEPELGHNDLLIKIRKTAICGTDVHI
                     YNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGG
                     RTHLCRNTIGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSF
                     DLVGEDVLVSGAGPIGIMAAAVAKHVGARNVVITDVNEYRLELARKMGITRAVNVAKE
                     NLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKV
                     IFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSG
                     KVILSWD"
     gene            complement(21441..22637)
                     /gene="kbl"
                     /locus_tag="RN951_002982"
     CDS             complement(21441..22637)
                     /gene="kbl"
                     /locus_tag="RN951_002982"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HDX2527953.1"
                     /translation="MRGDFYQQLANDLETARAEGLFKEERIITSAQQADITVADGSHV
                     INFCANNYLGLANHPELIAAAKAGMDSHGFGMASVRFICGTQDSHKELEQKLAAFLGM
                     EDAILYSSCFDANGGLFETLLGAEDAIISDALNHASIIDGVRLCKAKRYRYANNDMQE
                     LEARLKEAREAGARHVLIATDGVFSMDGVIANLKGVCNLADKYDALVMVDDSHAVGFV
                     GENGRGSHEYCDVMGRVDIITGTLGKALGGASGGYTAARKEVVEWLRQRSRPYLFSNS
                     LAPAIVAASIKVLEMVEAGSELRDRLWANARQFREQMSAAGFTLAGADHAIIPVMLGD
                     AVVAQKFARELQKEGIYVTGFFYPVVPKGQARIRTQMSAAHTSEQITRAVEAFTRIGK
                     QLGVIA"
     gene            22851..23831
                     /gene="rfaD"
                     /locus_tag="RN951_002983"
     CDS             22851..23831
                     /gene="rfaD"
                     /locus_tag="RN951_002983"
                     /EC_number="5.1.3.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-glyceromanno-heptose 6-epimerase"
                     /protein_id="HDX2527954.1"
                     /translation="MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVD
                     LNIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLH
                     YCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANS
                     QIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVA
                     DVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQAFT
                     QADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDINVNSQNHSSGIKAATK"
     gene            23911..24957
                     /gene="rfaF"
                     /locus_tag="RN951_002984"
     CDS             23911..24957
                     /gene="rfaF"
                     /locus_tag="RN951_002984"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-heptose--LPS heptosyltransferase RfaF"
                     /protein_id="HDX2527955.1"
                     /translation="MKILVIGPSWVGDMMMSQSLYRTLQARYPQAIIDVMAPAWCRPL
                     LSRMPEVNEAIPMPLGHGALEIGERRKLGHSLREKRYDRAYVLPNSFKSALVPFFAGI
                     PHRTGWRGEMRYGLLNDVRVLDKEAWPLMVERYVALAYDKGIMRTAQDLPQPLLWPQL
                     QVSEGEKSYTCNQFSLSSERPMIGFCPGAEFGPAKRWPHYHYAELAKQLIDEGYQVVL
                     FGSAKDHEAGNEILAALNTEQQAWCRNLAGETQLDQAVILIAACKAIVTNDSGLMHVA
                     AALNRPLVALYGPSSPDFTPPLSHKARVIRLITGYHKVRKGDAAEGYHQSLIDITPQR
                     VLEELNSLLLQEEA"
     gene            24961..>25912
                     /gene="rfaC"
                     /locus_tag="RN951_002985"
     CDS             24961..>25912
                     /gene="rfaC"
                     /locus_tag="RN951_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide heptosyltransferase RfaC"
                     /protein_id="HDX2527956.1"
                     /translation="MRVLIVKTSSMGDVLHTLPALTDAQQAIPGIKFDWVVEEGFAQI
                     PSWHAAVERVIPVAIRRWRKAWFSAPIKAERKAFREALQAENYDAVIDAQGLVKSAAL
                     VTRLAHGVKHGMDWQTAREPLASLFYNRKHHIAKQQHAVERIRELFAKSLGYSKPQTQ
                     GDYAIAQHFLTNLPTDAGEYAVFLHATTRDDKHWPEEHWRELIGLLADSGIRIKLPWG
                     APHEEKRAKRLAEGFAYVEVLPKMSLEGVARVLAGAKFVVSVDTGLSHLTAALDRPNI
                     TVYGPTDPGLIGGYGKNQVVCRAPDKDLAHLTAETVFNKIN"
BASE COUNT         6355 a         6773 c         6734 g         6050 t
ORIGIN      
        1 ttgtgatcta tagattaaat attttttaaa tgtgactgtc atccttcaga taataaagcc
       61 atcatcgcaa tagatggaaa agcactcctg ctcttttttg attagagccg tcgcaggagg
      121 aacaactcat atcatcattg cgatctcgac gatgtatagt ctcatcctgc ggcagaacaa
      181 gacggataaa aaatccaatg agagcacact catccagaac ttattaacat aatgaatatt
      241 aaagaaaaat catcgcagct aatgaagtaa tatgcaaaaa taattagtcc ttacaaggag
      301 caaagttcca taatctcccc cctccccctc aatgatccaa ataaagataa tgcatccagc
      361 tggtcattct tagcagcact ttccgcatca ccgaaacatg gctgaaatgg tcggagtaaa
      421 ccgccacctg ggcgtagatg ccgtcgggta aggcatcgat atcatcgtta gggtccagtt
      481 caatggttcc cagcacaccg tccgtgccgg gcacgaccgt taatgattgc aataccccct
      541 gcgcctgata agaaccgcct ggcacgacag gtaaaatact agtcagtttg ccgtgaaaca
      601 cctgcccagg tagcgcgtta aacaccactt ccgcatcatc gccgggtttc agacgtaaca
      661 gcgagttttg ccgaaattgg gcgacaattt gccgtttttg ctcggggatg aagaccatca
      721 ccggacgcag cggcaaggca gctgcgtatg tacctgggcg gatcagtacc tgagtaacgt
      781 agccattgct cggcgcgcga atgacagtct gctcaaggtt atattttgct tcagtaagtt
      841 gcgctcttaa gctcacaatc tgcgattgct cgccgttaac catactgtcg agctggctct
      901 ggatctgcgc ctgctccgcc accgagcctt tcaccagcgc atcctgcgcg aggaaatttt
      961 gccgcgcatc gtcgatgtca cgttccgaga acggattcac cgccgcctgg ctgcctttca
     1021 agtaacgttg ataattttta aacagacggt cgcgctccgc tgaaacctgg gtggtgttgg
     1081 cctgcgcttc agtgagctgc gcacgcagcg tctttatatt atgcgtcgcc gtcatcaggt
     1141 cagcctgaag tctgtcaact cgcgcctggt aacgaaccgg gtcgagctta aaaagcacct
     1201 cgcccttttg aataagctga ttattcttgt cagtgacttc agtaacaatt cccgtcacct
     1261 gtggcgtgat agggatcgct atcactgcct tttgcgcggt aaaagtgtaa gggtggttgt
     1321 agttcatcaa caaaatcaaa ccactcacca gaaacacgcc tcccagcgcc gccgtcgcca
     1381 gcgtccactg atttaccgga atgcggaaga ttttaaagac cgcccacgcc agcgccacgt
     1441 aagttaaaac aatcaataga tccataatta gatctccggg aacgtggaat agtcagtctt
     1501 tttctcggcg gcgagttgat gctccagccg ggaaattcgg tcagaaagtg cggcgatttc
     1561 cgggtcagtc gctttctcct gcgacgcaac atgtgactgc ataccccagc cacgctccgg
     1621 ttgatagagc gtcgcccaga tccacagaaa cggccagata acatgcagag taaacaggct
     1681 cacccagccc gccgtatgaa tagcgtcggc atggggatgg ttgcgctttt tggcaatcag
     1741 ataagggatg tcatgtatcg cgatgattcc ataaaaaatc accagaaaga cgaagatcag
     1801 cactcccaac gcgaaatagt ttagaaacat atctgcctcg gattcacgtt tatcagtgtt
     1861 gtttttgggc tggcagccag aagggagtca ggctgatatt ttgacaataa tccgggttcg
     1921 cgattctcgc cataacacca aagaataatt tttagaggtg atgagttgct tagttacata
     1981 acgattgtat gacgaaggca taacatgctg tagatcacat caggtgaacg ccgtaagaaa
     2041 atatcttgtg attcagatca caaagattca acaaaccatc aaaacaaaaa tgtgacacta
     2101 ctcacattta aatgccattt ttagcgaaaa tcgccgcctt gttgcttttt tacacaagcg
     2161 ttttgtgatg aacgtcacgt caattacctc tctaccccct atatttatgt gattgatatc
     2221 acacaaaagg ccgtcgactg gacagttaac cgattcagtg ccagatttcg cagtatctac
     2281 aaggtccggc tacctctgcc gccacattaa caaaaaacct cgggcttcca gcctgcgcga
     2341 cagcaaacat aagaaggggt gtttttatgt catccgatat taagatcaaa gtgcaaagct
     2401 ttggtcgttt cctcagcaac atggtgatgc caaatatcgg cgcgtttatc gcgtggggta
     2461 tcatcaccgc gttatttatt ccaacagggt ggttaccgaa cgagacgctg gcgaagctgg
     2521 tcgggccgat gatcacttat ctcctgccgc tgctgatcgg ttataccggt ggtaagctgg
     2581 taggcggcga acgtggcggc gtagtcggtg ccatcaccac catgggcgtt atcgtcggcg
     2641 cagacatgcc gatgttcctc ggttctatga ttgcaggtcc gctgggcggc tggtgcatta
     2701 agcacttcga ccgctgggta gacggtaaga tcaaatccgg ttttgagatg ctggtgaata
     2761 acttctccgc aggcatcatc gggatgatcc tcgctattct ggcattcctc ggcattggcc
     2821 cgattgttga agccctgtcc aaaatgctgg ctgcgggcgt taacttcatg gttgtccatg
     2881 acatgctgcc gctggcgtct atctttgttg aaccggcgaa aatcctgttc ctcaacaacg
     2941 ccattaacca cggtatcttc tcgccgctgg gtattcagca gtcccatgaa ctgggtaaat
     3001 caatcttctt cctgattgaa gctaacccag gtccaggtat gggcgtgctg ctggcgtaca
     3061 tgttctttgg tcgtggtagc gctaaacagt ctgcgggcgg tgcggcaatc atccacttcc
     3121 tggggggtat ccacgaaatc tacttcccgt atgtgctgat gaatccgcgt ctgatcctcg
     3181 cagtcatcct cggcggtatg actggcgtgt tcacgctgac tatcctgggc ggtggtctgg
     3241 tttctccggc atctccgggt tctatccttg ctgtactggc gatgacacca aaaggtgctt
     3301 acttcgctaa catcgcgggt gtgtgtgcgg cgatggctgt ctccttcgtt gtctctgcta
     3361 ttttgctgaa aaccagcaaa gtgaaagaag aagatgatat tgaagcagca actcgtcgta
     3421 tgcaggacat gaaagctgag tctaaaggcg catctccgct gtctgctggc gatgtgacta
     3481 acgacctgag ccacgtacgt aaaatcatcg ttgcctgtga cgccggtatg ggttccagtg
     3541 cgatgggcgc aggcgttctg cgtaagaaaa ttcaggatgc aggtctgtcg cagatttctg
     3601 ttactaacag cgcgatcaac aacctgccgc cagatgtgga cctcgtcatc actcaccgtg
     3661 acctgaccga acgcgctatg cgccaggttc cgcaggcaca gcatatttcg ctgaccaact
     3721 tcctcgacag cggcctgtac accagcctga ccgaacgtct ggttgctgcc caacgccaca
     3781 cggcaaacga agagaaagta aaagacagcc tgaaagacag ctttgacgat tccagtgcta
     3841 acctgttcaa gctaggcgcg gagaacatct tcctcggtcg caaagcggca accaaagaag
     3901 aagcgattcg ttttgctggc gagcagctgg tgaaaggcgg ttacgttgag ccggaatacg
     3961 ttcaggcgat gctggatcgt gaaaaactga ccccgactta tctgggtgag tctatcgcgg
     4021 tgccacacgg tacggttgaa gcgaaagatc gcgtactgaa aacgggcgtc gtgttctgcc
     4081 agtacccgga aggcgtgcgc ttcggtgaag aagaagatga cattgcccgt ctggtgattg
     4141 gtattgctgc ccgtaacaac gagcacattc aggttatcac cagcctgacc aatgcactgg
     4201 atgatgagtc cgtcatcgag cgtctggcac acaccaccag cgtggatgaa gtgctggaac
     4261 tgctggcagg tcgtaagtaa tccaatccca ccctctccac atggagaagg tggggttaat
     4321 tgcctgatgc gctacgctta tcaggcctac aggatgcatc acaatttgtt gaatttgcac
     4381 gttcttgtag gccggataag gcgcttacgc cgcatccggc gctgcccctc tcctcacgga
     4441 gagggtttgg gtgagggaaa agcctcaccc cagccctctc gggtaaaaac attgatgaag
     4501 gttaatacta tgaaagcatt acattttggc gcaggtaata tcggtcgtgg ctttatcggt
     4561 aaactgctgg cagacgcggg tatccaactg acgtttgccg atgtcaatca ggtggtactt
     4621 gatgccctga atgcccgtca tagctatcag gtacatgtgg ttggtgaaac cgagcaggta
     4681 gataccgttt ccggcgtcaa tgctgtcagc agcattggtg atgatgtcgt tgatctgatt
     4741 gctcaggttg atttagtcac taccgccgtt ggcccggttg tgctggaacg tattgctccg
     4801 gcaatcgcca aagggctggt gaaacgtaaa gaacaaggta atgaatcccc gctgaacatc
     4861 atcgcctgtg aaaacatggt acgcggtacc acgcagctga aaggccatgt gatgaacgcc
     4921 ctgccggaag acgccaaagc gtgggtagaa gaacacgttg gctttgtcga ttccgccgtt
     4981 gaccgcatcg taccgccttc ggcttcggca actaacgatc cgctggaagt gacggtagaa
     5041 accttcagcg aatggattgt cgataaaacg cagttcaaag gcgcactgcc gaacatccca
     5101 ggcatggagt taaccgacaa cctgatggca tttgtcgaac gtaaactctt caccctgaac
     5161 acgggtcatg ctataaccgc gtacctcgga aaactggccg gtcatcagac cattcgtgac
     5221 gcgattctcg acgagaaaat ccgcgcggtg gtaaaaggtg cgatggaaga aagtggtgca
     5281 gtattgatca agcgctacgg ctttgacgct gacaagcatg cggcgtacat ccagaaaatt
     5341 ctcggccgtt ttgagaaccc gtatctgaaa gatgatgtag agcgcgtagg ccgtcagcca
     5401 ctgcgtaaac tgagtgctgg cgaccgtctg atcaagccac tgctcggtac gctggaatat
     5461 ggtctgccac ataaaaacct gattgaaggt attgccgctg caatgcactt ccgcagtgaa
     5521 gatgatccgc aggctcagga actggcagca ctgatcgctg acaaaggtcc gcaggcggcg
     5581 ctggcacaga tttccggtct tgatgccaac agcgaggttg tatccgaggc ggtaaccgct
     5641 tataaagcaa tgcaataatg gtggaccagg cgcaggacac cctgcgcccg aataacagat
     5701 tgtcagatat gcaggcaaca atggaacaaa cccaggcctt tgaaaaccgt gtgcttgagc
     5761 gtctgaatgc tggcaaaacc gtgcgaagct ttctgatcac cgccgtcgag ctcctgaccg
     5821 aggcggtaaa tcttctggtg cttcaggtat tccgcaaaga cgattacgcg gtgaagtatg
     5881 ctgtagaacc gttactcgac ggcgatggtc cgctgggcga tctttctgtg cgtttaaaac
     5941 tcatttacgg gttgggcgtc attaaccgcc aggaatacga agatgcggaa ctgctgatgg
     6001 cattgcgtga agagctaaat cacgacggca acgagtacgc ctttaccgac gacgaaatcc
     6061 ttggaccctt tggtgaactg cactgcgtgg cggcgttacc accgccgcca cagtttgaac
     6121 cagcagactc cagtttgtat gcaatgcaaa ttcagcgcta tcaacaggct gtgcgatcaa
     6181 caatggtcct ttcactgact gagctgattt ccaaaatcag cttaaaaaaa gcctttcaaa
     6241 agtaagcaac gtctgcttac tgcccctcta cctgcttcgg ccgataaagc cgacgataat
     6301 actccagacg ttgtagatat aacggcacgc tttcatcggg tattccggac ggaatcgcgt
     6361 tacggggagg aagttttttc agatactccc ggaacgcctg gcttgatgcc atgaaatcta
     6421 cggctttatc gataagaagc ggaacgtttt cacctaattt gcccatgatg atatctccgt
     6481 attaccccgc gccgggaatg cgcggccgcc aattttagtt taggttcccg gtaaagatga
     6541 cattaaggaa aacgtgctga atcctcaata atcatccgct gctgtttatt atcttttttc
     6601 tatagatttc ttaattaatc aacgaattgc gtagtttttg agcatgttaa tgattacgtt
     6661 acagaactat tacaatgtca ttagttgtga acaaagcacc tggtcgcgca tactaggggc
     6721 tataaattta tctttatcag aagccatcac atgaaagaag tcgaaaaaaa cgaaatcaaa
     6781 cgtctcagcg atcgcctgga cgccatccgc caccagcagg ccgatctttc gctggttgaa
     6841 gccgcagaca aatatgccga gctggaaaaa gagaaagcca cgctggaagc agaaattgct
     6901 cgcctgcgtg aagttcatag ccaaaaactg agtaaagaag cacagaagct gatgaagatg
     6961 ccattccagc gcgcaattac caaaaaagag caggctgata tgggcaagct gaagaaaagt
     7021 gttcgcggac tggtcgttgt gcacccaatg accgcactgg gccgcgaaat gggcctgcag
     7081 gagatgactg ggttttcaaa gaccgcgttt taagaacaca gtatctacag ggtgattctg
     7141 cacattccta taggccgagt aaggtgttca cgccgcatcc ggcaagataa ggcgctctgg
     7201 atcaacaacc taagggcaat tctctgatga ggattgccct tttctttacc agacatctcc
     7261 ccccacaaga attggcccta ccaattcttc gcttatctga cctctggttc acaatttccc
     7321 aattaaaact cacatcaatg ttgccaatac ataacattta gttaaccatt cattgtcatt
     7381 atccctacac aacacaattg gcagtgccac ttttacacaa cgtgtgacaa ggagatgagc
     7441 aacagactca ttacacgatg tgcgtggact ccaggagacc tgcaatgaat ctctggcaac
     7501 aaaactacga tcccgccggg aatatctggc tttccagtct gatagcatcg cttcccatcc
     7561 tgtttttctt ctttgcgctg attaagctca aactgaaagg atacgtcgcc gcctcgtgga
     7621 cggtggcaat cgcccttgcc gtggctttgc tgttctataa aatgccggtc gctaacgcgc
     7681 tggcctcggt ggtttatggt ttcttctacg ggttgtggcc catcgcgtgg atcattattg
     7741 cagcggtgtt cgtctataag atctcggtga aaaccgggca gtttgacatc attcgctcgt
     7801 ctattctttc gataacccct gaccagcgtc tgcaaatgct gatcgtcggt ttctgtttcg
     7861 gcgcgttcct tgaaggagcc gcaggctttg gcgcaccggt agcaattacc gccgcattgc
     7921 tggtcggcct gggttttaaa ccgctgtacg ccgccgggct gtgcctgatt gttaacaccg
     7981 cgccagtggc atttggtgcg atgggcattc caatcctggt tgccggacag gtaacaggta
     8041 tcgacagctt tgagattggt cagatggtgg ggcggcagct accgtttatg accattatcg
     8101 tgctgttctg gatcatggcg attatggacg gctggcgcgg tatcaaagag acgtggcctg
     8161 cggtcgtggt tgcgggcggc tcgtttgcca tcgctcagta ccttagctct aacttcattg
     8221 ggccggagct gccggacatt atctcttcgc tggtatcact gctctgcctg acgctgttcc
     8281 tcaaacgctg gcagccagtg cgtgtattcc gttttggtga tttgggggcg tcacaggttg
     8341 atatgacgct ggcccacacc ggttacactg cgggtcaggt gttacgtgcc tggacaccgt
     8401 tcctgttcct gacagctacc gtaacactgt ggagtatccc gccgtttaaa gccctgttcg
     8461 catcgggtgg cgcgctgtat gagtgggtga tcaatattcc ggtgccgtac ctcgataaac
     8521 tggttgcccg tatgccgcca gtggtcagcg aggctacagc ctatgccgcc gtgtttaagt
     8581 ttgactggtt ctctgccacc ggcaccgcca ttctgtttgc tgcactgctc tcgattgtct
     8641 ggctgaagat gaaaccgtct gacgctatca gcaccttcgg cagcacgctg aaagaactgg
     8701 ctctgcccat ctactccatc ggtatggtgc tggcattcgc ctttatttcg aactattccg
     8761 gactgtcatc aacactggcg ctggcactgg cgcacaccgg tcatgcattc accttcttct
     8821 cgccgttcct cggctggctg ggggtattcc tgaccgggtc ggatacctca tctaacgccc
     8881 tgttcgccgc gctgcaagcc accgcagcac aacaaattgg cgtctctgat ctgttgctgg
     8941 ttgccgccaa taccaccggt ggcgtcaccg gtaagatgat ctccccgcaa tctatcgcta
     9001 tcgcctgtgc ggcggtaggc ctggtgggca aagagtctga tttgttccgc tttactgtca
     9061 aacacagcct gatcttcacc tgtatagtgg gcgtgatcac cacgcttcag gcttatgtct
     9121 taacgtggat gattccttaa tgattgtttt acccagacgc ctgtcagacg aggttgccga
     9181 tcgtgtgcgg gcgctgattg atgaaaaaaa cctggaagcg ggcatgaagt tgcccgctga
     9241 gcgccaactg gcgatgcaac tcggcgtatc acgtaattca ctgcgcgagg cgctggcaaa
     9301 actggtgagt gaaggcgtgc tgctcagtcg acgcggcggc gggacgttta ttcgctggcg
     9361 tcatgacaca tggtcggagc aaaacatcgt ccagccgcta aaaacactga tgaccgatga
     9421 tccggattac agtttcgata ttctggaagc ccgctacgcc attgaagcca gcaccgcatg
     9481 gcatgcggca atgcgcgcca cacctggcga caaagaaaag attcagcttt gctttgaagc
     9541 aacgctaagt gaagacccgg atatcgcctc acaagcggac gttcgttttc atctggcgat
     9601 tgccgaagcc tcacataaca tcgtgctgct gcaaaccatg cgcggtttct tcgatgtcct
     9661 gcaatcctca gtgaagcata gccgtcagcg gatgtatctg gtgccaccgg ttttttcaca
     9721 actgaccgaa caacatcagg ctgtcattga cgccattttt gccggtgatg ctgacggggc
     9781 gcgtaaagca atgatggcgc accttagttt tgttcacacc accatgaaac gattcgatga
     9841 agatcaggct cgccacgcac ggattacccg cctgcccggt gagcataatg agcattcgag
     9901 ggagaaaaac gcatgattat ttccgcagcc agcgattatc gcgccgcagc gcaacgcatt
     9961 ctgccgccgt tcctgttcca ctatatggat ggtggtgcat attctgaata cacgctgcgc
    10021 cgcaacgtgg aagatttgtc agaagtggcg ctgcgccagc gtattctgaa aaacatgtcc
    10081 gacttaagcc tggaaacgac gctgtttaat gagaaattgt cgatgccggt ggcactggct
    10141 ccggtgggtt tgtgtggcat gtatgcgcgt cgtggcgaag ttcaggcagc caaagcggcg
    10201 gacgcgcatg gtattccgtt tactctctcg acggtttccg tttgcccgat tgaagaagtc
    10261 gcgccagcca tcaagcgccc aatgtggttc cagctttatg tactgcgcga tcgcggcttt
    10321 atgcgtaacg cgctggagcg agcaaaagca gcgggttgtt cgacgctggt tttcaccgtg
    10381 gatatgccga caccgggcgc acgctaccgt gatgcgcatt caggtatgag cggcccgaac
    10441 gcggcaatgc gccgctactt gcaagcggtg acacatccgc aatgggcgtg ggatgtgggc
    10501 ctgaacggtc gtccacatga tttaggtaat atctcagctt atctcggcaa accgaccgga
    10561 ctggaagatt acatcggctg gctggggaat aacttcgatc cgtccatctc atggaaagac
    10621 cttgaatgga tccgcgattt ctgggatggc ccgatggtga tcaaagggat cctcgatccg
    10681 gaagatgcgc gcgatgcagt acgttttggt gctgatggaa ttgtggtttc taaccacggt
    10741 ggccgccagc tggacggtgt actctcttcc gcccgtgcac tgcctgctat tgcagatgcg
    10801 gtgaaaggtg atatagccat tctggcggat agcggaattc gtaacgggct tgatgtcgtg
    10861 cgtatgattg cgctcggtgc cgacaccgta ctgctgggtc gtgctttctt gtatgcgctg
    10921 gcaacagcgg gccaggcggg tgtagctaac ctgctaaatc tgatcgaaaa agagatgaaa
    10981 gtggcgatga cgctgactgg cgcgaaatcg atcagcgaaa ttacgcaaga ttcgctggtg
    11041 caggggctgg gtaaagagtt gcctgcggca ctggctccca tggcgaaagg gaatgcggca
    11101 tagtcgtttg cgccccctca ccctaaccct ctccctcagg gagaggggac cgttcggcgc
    11161 tgtatgtact ccctcactct gaaacgacac cgcactcttt ttttctccct cgcccctccg
    11221 gggagagggc cggggtgagg ggaaaaggcc gcactgctca ccaattttct gctatcctgc
    11281 ccccgcacta agggggcagt atgctaaaca tcgtacttta cgaaccagaa attccgccaa
    11341 atactggcaa catcatccgt ctttgcgcta ataccggctt tcgtctgcat atcatcgaac
    11401 cgatgggatt tgcctgggac gataagcgcc tgcgccgcgc ggggctggac tatcacgagt
    11461 ttaccgccgt tacgcgtcat catgactatc gcgcgttcct cgaagcagaa aatccccagc
    11521 gcctgttcgc cctcaccacg aaaggtacac ctgctcacag cgccgtaagc tatcaggatg
    11581 gcgattatct gatgttcggc ccggaaacac gcggcctgcc agcgagcatt cttgatgccc
    11641 tgcccgctga acaaaaaatt cgcattccga tggtgccgga cagccgcagc atgaatctgt
    11701 ccaatgcggt gtcggtagtg gtgtatgaag cctggcggca gttggggtat ccgggagcgg
    11761 tattgagaga ttagttactg taggccggat agatgattac atcgcatccg gcacgatcac
    11821 aggacattag atcccatccc catactcaaa tgtatggtta ataccgttga aatgctggtc
    11881 catatccatt gatggcttat cgctgtctgg tttaccgaca atacgagccg gaacgccagc
    11941 ggcggtggta tgcggcggca ccggttgcag caccacggaa cctgcgccaa tcttcgcgcc
    12001 gcgaccaact tcaatattgc cgaggatttt cgcgcccgcg ccaatcatca caccttcacg
    12061 aattttcggg tgacggtcac caccagattt acccgtaccg ccaagcgtca cagattgcag
    12121 aatcgatacg tcgttttcaa ttaccgccgt ttcacccaca acgatgcccg tggcgtggtc
    12181 gagcataatg ccacggccaa tttttgctgc cgggtgaata tcgacctgga acgtcacaga
    12241 aacctggttt tgcagaaaga ttgccaatgc gcgacgcccc tgattccaca accagtgacc
    12301 gatgcgatag gcctgcaagg catgaaaacc cttcaggtat aacaacgggg ttgagtattt
    12361 atcgactgcc gggtcgcggg tacgcaccgc ctgaatatca caggccgcag aggcgatcat
    12421 ttccgggtca gcggcgtagg cttcttccac cacttcacgg atagcaatag caggcataat
    12481 tggcgatgac agcttgttcg ccagcatgta gctcagtgca cttccaaggt tttcgtgctt
    12541 gagtagcgtc gcgtggtaaa aactggccag cattggctca cagtccgcca gcgttctggc
    12601 ttcggcttta atattgttcc agacaatttc cagttcttca cacgacattg cttactccac
    12661 acgatgagat aatgaccggc ccgttctgcg cgggccgggt catagcggta acaaaggttc
    12721 cctggggtta gtggctgctg cgctcgtcct tgcgtgcacg acctaataac gtcaatgctg
    12781 cctcgcgcgc gttttttccg caatataata cttgataaat ttcctcggtt attggcattt
    12841 ctacgccgaa gcgatgcgcc agttcgcgga cttctttcgt attgcggtag ccttccacca
    12901 cctgaccaat cttctcctgc gcgctttgta catccatgcc ctgaccgagc atcatgccaa
    12961 aacggcggtt acgcgactgg ttgtcggtac aggtaagcac cagatcgcca agccccgcca
    13021 tgcccataaa ggtggcaggg tcggcaccca gcgccgcgcc aagacgcgac atttcagcca
    13081 gcccacgggt gatcagcgcc gtacgcgcat tcgcaccaaa accgataccg tcggacatcc
    13141 ccgcaccaat ggcaatgacg tttttcaccg cgccgccaag ctgcacgcca atgaaatccg
    13201 ggttactgta aacgcggaaa cttttgccgc agtgcagcag ctgctgaaga tcatcagcaa
    13261 aggtctgatc ggtcgaggcc agcgaaatag ctgtcggtaa acctgccgcc agttctttcg
    13321 caaacgttgg gccagagata accgccagcg gaatttgatc gcctaacgcc tcgcgggcca
    13381 cgtcctgtaa cagacgcccg gtttccgctt ccagcccttt ggtcgcccac accagacgcg
    13441 catcaggacg catcagcggt ttaatctggc gcagcacttc accaaagaca tggctgggta
    13501 cgacgacgag aatattacgg ctggctgcca gcgcagtggc gagatcgctt tcaagatgga
    13561 gcgtatcggg aaaaggcaca tcggggagaa acgcggcgtt acagcggtcg cgttcaagcg
    13621 ttgcgatatg ttcagggtca tggccccaga ggacaacctc gtggccattt cttgccaggg
    13681 taatggcaag agcggtgccg tacgagccgg caccgatcac agtcattgaa gcattacgtt
    13741 ggttcatcag gcatcctgat gttcttcagt accttcgcca gcctgctgct gcaaatagtt
    13801 catgaacagc gcatcgaagt taaccggcgc aaggttcagt tgcgggaatg taccgcggga
    13861 taccatgctg gtgatgcact cacgagcata cgggaacaga atgttcgggc agtatgcgcc
    13921 caggcaatgt gccatctggg tgccttcgat acccgcgatg gagaaaatac cgccctgctg
    13981 aacttcacac aggaacgcgg tttcttcgcc cagggaggcc gttacggtaa cacgcagtac
    14041 cacttcgtaa acgtcatctg ccagttgagt agatgccgta tccagatcaa gtttaacttc
    14101 tggctgccaa tctttctgga aaacgtgcgg cgcgttcggc gcttcgaaag aaatatcctt
    14161 ggtataaata cgttggatct ggaaagtcat ttcggtgttg ttttgttctg acatgtgtag
    14221 aaaaccctta agtgttgtcc ttaaatactg cgcaatgtaa tgccaacgtt cacacgttat
    14281 ttcagcaggg gatccagtcc accacgtgca tccaatgcat acaagtcatc acagccgcca
    14341 atgtgctgtg cgtcaataaa aatctgggga accgtggtgc gaccgctgcg tttgatcatc
    14401 tcttcacgct tggcggcatt gccatcgatc ggcaactcct gaaaactcac gcccttgctg
    14461 ctcagcagtg cttttgcacg atggcaatac gggcaggttt ctttggtata gatttcaaca
    14521 ttggccataa tttagctcct gtttttttac cctgaaattt catgttgcag ggcggctgca
    14581 aaatggagtg tccccagaag cttataacaa taagtcgctg ggggcctaat tgcagctaac
    14641 ggcctgcatc atgaaagacg acaggtaaat tatttgccgc gcaccaaagg caagttttcg
    14701 ccagcccagc cagcgacgcc ttctttcagc acgaatactt gcgcaaaacc agctttcgtc
    14761 agtgcgtttg caggctcctg gcactgcatg ccagaaccgt ctaccacgat aaccggtttg
    14821 tctttgtgct tctcaagctc accaacattg ttggctttga tttcgctcgg caacagattg
    14881 atagaacctg cgatatggcc tttacggaag tcatcacgct gacgtaaatc cacaaccaca
    14941 gcgtcttctt tgttgatcag acgcgtagct tcaccacgag taatcacctt cactttcgag
    15001 gtcaggctct taaacgtagt cacaagaacc gccaccagta acgcgatcca ggcgatactc
    15061 agtatgggat gacggccaac aaattgcata atttcttgca tggggggtaa caactcccga
    15121 cgtagtgatt aaaaaaacca ggaaaggagt atacctgcgc ggtgcggcaa atacagccag
    15181 cgcgttagct ggaatgcaat tttgcggggc acgacgaaaa aaaagcgcaa atctggcatc
    15241 ggcttgccgc gagcggtcgt atattttgat cttcagaggc tattttatcg attcagctgt
    15301 agtaaaatta cgcaaatttt gactcttgag tatgaggttg tcgcaatgtc ggtttctaaa
    15361 aaacctatgg tactggtgat tctggatggc tatggctatc gtgaagaaca gcaggataac
    15421 gccattttta gtgctaaaac cccggtaatg gatgcactgt gggccaatcg tccgcatacc
    15481 ctgatcgacg cttccggtct ggaagtcggt ctgcctgacc gtcagatggg taactccgaa
    15541 gtaggccacg ttaacctggg tgccggccgc atcgtgtatc aggacctgac tcgtctggac
    15601 gttgaaatca aagatcgcgc tttctttgct aatccagtgc tgactggcgc ggtagataaa
    15661 gcgaaaaacg caggtaaagc agtacacatt atgggtctgc tctccgcagg cggcgtacac
    15721 agccacgaag atcacatcat ggcgatggta gaactggcag ctgaacgcgg cgcagaaaaa
    15781 atctacctgc acgcattcct tgacggtcgc gacaccccgc cgcgcagtgc tgaatcctcg
    15841 ctgaaaaaat ttgaagagaa atttgctgcg ctgggtaaag gccgcgtagc gtccatcatt
    15901 ggtcgttact acgcgatgga ccgcgataac cgttgggatc gcgttgaaaa agcctatgac
    15961 ctgctgactc tggcgcaggg tgagttccag gccgatactg ccgttgctgg tttgcaggca
    16021 gcttatgctc gcgacgaaaa cgacgagttc gtgaaagcga ccgttattcg tgcagaaggt
    16081 cagccagatg cggcaatgga agacggcgat gcgctgattt tcatgaactt ccgtgctgac
    16141 cgcgcgcgcg aaatcactcg tgcattcgta aacgcagatt tcgacggctt cgcgcgtaag
    16201 aaagtggtta acgtcgattt cgtgatgctg accgaatacg ccgctgacat caaaactgcg
    16261 gttgcttacc cacccgcttc cctggttaac accttcggcg agtggatggc gaaaaacgac
    16321 aaaactcagt tgcgtatttc cgaaaccgaa aaatatgccc acgttacttt cttcttcaac
    16381 ggtggcgtag aagagtcgtt caaaggcgaa gatcgcattc tgatcaactc accgaaagtg
    16441 gctacctacg atctgcaacc ggaaatgagc tccgcagagc tgaccgaaaa actggttgcg
    16501 gccatcaaga gcggcaaata cgacaccatt atctgtaact atccgaacgg tgacatggta
    16561 ggtcacaccg gggtgatgga agcggcggtt aaagcggttg aagcactgga tcactgcgtg
    16621 gaagaagtcg cgaaagcggt tgagtccgtg ggtggacaac tgctgatcac cgctgaccac
    16681 ggtaacgctg aacagatgcg cgatccggca acgggtcagg cacacacggc acacaccaac
    16741 ctgccagttc cgctgattta cgttggtgat aagaacgtga aagcggttgc aggcggcaaa
    16801 ctttctgaca tcgcgccgac catgttgtcg ctgatgggta tggaaatccc gcaagagatg
    16861 actggtaagc cgctgttcat cgtggaataa tccctcccca tgaggggaaa ggcgattaat
    16921 accatgacac gggccgtgaa accgcgcagg tttgcaatca ggcccatcat ctacgccagc
    16981 gttcttagcg ctggcgtatt gttgtgcgcc ttttccgccc atgcggatga gcgtgaccaa
    17041 ctcaaatcta ttcaggccga tatcgccgcg aaagagcgcg cggtacgcca aaagcaacaa
    17101 caacgcgcaa gcctgctcgc acaattgaaa aagcaggaag aagcgatctc tgaagccacc
    17161 cgtaagctgc gcgaaacgca aaacacgctc aatcaactca ataaacagat tgatgagatg
    17221 aacgcgtcga ttgccaaact ggagcagcaa aaagccgccc aggagcgcag cctcgccgca
    17281 caactggatg ccgcattccg tcagggcgag cataccggta ttcagctgat tctcagcggt
    17341 gaagaaagcc agcgtggaca gcgtttacag gcttatttcg gctatctcaa ccaggcgcga
    17401 caagaaacca ttgcccagtt gaagcaaacg cgtgaagaag tcgccatgca gcgtgctgaa
    17461 ctggaagaga aacaaagcga gcaacaaacg ctgttatatg aacagcgcgc ccaacaggcg
    17521 aaactgactc aggctctgaa tgagcgtaaa aagacgctgg cggggctgga atcttccatc
    17581 cagcaaggtc agcagcagct aagtgaactg cgtgccaacg aatcccgtct gcgtaacagc
    17641 attgcccgtg cggaagccgc ggcgaaagcg cgtgcagaac gagaagcacg tgaggcccag
    17701 gcggttcgcg accgccagaa agaagcgacg cgcaaaggca ccacctacaa accgaccgaa
    17761 agcgaaaaat cgctgatgtc ccgaactggt ggcctgggtg cgccgcgtgg tcaggcattc
    17821 tggccggttc gcgggccgac gctgcatcgc tatggcgagc agctacaggg tgaattacgc
    17881 tggaaaggga tggtgattgg tgcctctgaa ggtactgaag ttaaagcgat tgccgacggt
    17941 cgggtgattc tggctgactg gctgcaaggc tacggtctgg tggtggtggt tgagcatggt
    18001 aaaggcgaca tgagtcttta cggctataat cagagcgcac tggtgagcgt tggttcgcag
    18061 gttcgcgcgg gccagccaat tgcactggtg ggcagcagtg gcggtcaggg tcggccttca
    18121 ctctatttcg aaattcgccg ccagggtcag gcggtcaatc cacagccgtg gttgggaaga
    18181 taagttttgt ttccatttcg tcgtaacgtt cttgcatttg ccgctctgtt ggcgctctcc
    18241 tcccccgtac ttgctggcaa acttgccatc gtcattgatg attttgggta tcgcccgcac
    18301 aacgaaaacc aggtgctggc gatgccctcc gctatctccg tcgctgtatt acccgattca
    18361 ccgcacgcca gagagatggc gaccaaagcg cataacagcg ggcacgaagt gttgattcat
    18421 ctcccgatgg caccactgag taaacagccg ctggagaaaa atacgctgcg cccggagatg
    18481 agcagcgacg aaattgagcg cattattcgt agtgcggtca ataacgtgcc ctatgccgtg
    18541 gggatcaaca accacatggg tagcaagatg acctctaacc tgtttggtat gcagaaagtg
    18601 atgcaggcac tggagcgtta caatctttac ttcctcgaca gcgtaaccat cggtaatacc
    18661 caggcgatgc gcgccgcgca aggtactggc gtgaaggtga tcaaacggaa ggtgttcctc
    18721 gacgattcgc agaacgaagc ggacatccgt gtgcaattta atcgcgcaat tgatctggcg
    18781 cgtcgcaacg gttcaaccat tgccattggg catcctcacc cttcaacggt acgcgtgcta
    18841 caacagatgg tttataacct gccgccagac attacgctgg tgaaagccag cagcttgctg
    18901 aatgaaccgc aggttgatac ttctacaccg ccgaaaaacg ctgtgcctga tgcaccgcgt
    18961 aatccgttcc gtggcgtgaa gctgtgcaaa ccgaagaaac cgatagaacc tgtttatgct
    19021 aatcgcttct ttgaagtatt aagcgaaagc atcagccaga gcacgctgat cgtttacttc
    19081 cagcatcagt ggcaaggctg gggcaaacag cccgaagcgg cgaagtttaa cgctagcgca
    19141 aattaaaggc gctacgcgta atgcgatggt gcgaccgcgt tttgtcgcgc cattgccata
    19201 agcggaaaga ccacagtaac gcctggtaac cgaccttcac gctgcgcaca ttggtaatca
    19261 ggcgcttata cataccggaa gtaaatatct cggcaatcat ccgttggcgg gtaagaatat
    19321 ccggctcttt gcgcaccgca tggcaaacac gcaatgcctc gtaagttatt tgctgatgaa
    19381 attccggata aatcataatt ttgtcggcat aatttcgatt taatttctcc agcaggcggg
    19441 taatcttaat atagtgacgt tgataattaa ggtttttatt cccttgtcta tgcaaccgac
    19501 tcactgacgt attatgcaga taatatttat ataatgattg ctcggtatat cgcgcacgca
    19561 gcgcgttaaa catgaattct gttgtccaga caatatcctg atgatgtaat ccggcaataa
    19621 atttaatgtt atttttaaca ataacatcac ggcgataaac ccccatccag acaacgtgag
    19681 tccaacggcg cgaagaaagc cccatccgca gccagtccgg gccggttaag acgccggttg
    19741 agcgaaggcg atcggtgggg atggattgcc aggtttctcc cgtttcacga aaacaccagt
    19801 cagcgttgca ctgcgccacg tcgaggtcgt cctctaacgc catggtcatc agcgtttcgt
    19861 acatggtggg atagacttca tcgtcagcat cgacaaaagc gacatatttg cccgttgcca
    19921 cttcaatccc acgattacgc gccaccgatg cgccagcatt cgcctgatgc aacaaacgaa
    19981 cgtgcggata gttttctgcg taatgctttg ctatttcaac agaattatcc gttgaaccat
    20041 cgttaataat aatgatttcc agagcagtcc aggtttgcgt aattaaagat tccatacaag
    20101 tgcggaaatc atcgcccgca ttatataacg gaataataac actaagttta ttggtgctgt
    20161 tcatcataaa ttaccgacga cctctgaagt tatcctgacg ttttacaggc tttgtattaa
    20221 gaaactatta agcctgtgag atattatttt tacaggtgag agagtcactt cagggtagag
    20281 agataatgag agcagctata taagagatca gcacaattac gaactcttta ttacactgac
    20341 aggattttac atatttaaca gattatcctc agataaaagg gctggaatac cagcccttgt
    20401 tcgtgttaat cccagctcag aataactttc ccggactggc ccgaacgcat agcgtcaaag
    20461 cccttctgga aatcatcgat agagaaacga tgggtaatga tcggcgagag atcgaggcca
    20521 gactgaatca gcgccgccat cttgtaccag gtttcaaaca tctcacgacc gtaaatgcct
    20581 ttaatgaaca agcccttaaa gatcactttt gtccagtcta tcgacatgtc agaaggtgga
    20641 atacccaaca tcgcaatacg accgccgtgg ttcatggtgt cgagcatggt acgaaacgct
    20701 ggcggcgcac cggacatttc cagaccgaca tcaaagcctt cggtcatacc cagttctgcc
    20761 atcacatcat taaggttttc tttagcgacg ttgaccgcac gggtgatacc cattttgcgc
    20821 gccagttcga gacgatattc attaacatcc gtgatcacca cattgcgtgc accaacgtgt
    20881 ttcgccaccg ccgcagccat aatacctatc ggacctgcac cagagaccag cacatcctcg
    20941 ccaaccagat cgaacgacag cgcggtatgc acggcattac cgaagggatc aaaaatggaa
    21001 gccagatcgt cggagatatt gtcgggaatt ttgaaggcgt tgaacgccgg aatcaccaga
    21061 tattcggcga agcagcccgg gcggttaacg ccgacgccga tcgtgttgcg gcacagatgg
    21121 gtacgaccgc cacgacagtt gcgacagtga ccgcaagtga tatggccttc gccagaaacg
    21181 cgatcgccaa tcttgaagcc tttcacttcc tgaccaatac ctaccacttc accgacatat
    21241 tcatggccca cgaccatcgg caccgggatg gttttttgcg accactcatc ccagttatag
    21301 atgtgaacgt cagtcccgca gatggctgtt ttacggattt taatcagcag atcgttatga
    21361 cccagttccg gctcaggaac gtcggtcatc cagatgcctt cttccgcttt cagtttggat
    21421 aacgctttca tttcacatcc tcaggcgata acgcccagtt gtttaccaat acgcgtgaat
    21481 gcttctactg cgcgcgtaat ttgctcagag gtatgcgccg cagacatctg ggtacgaata
    21541 cgcgcctgac ctttcggaac gaccggatag aagaaaccgg tgacgtaaat cccctctttt
    21601 tgcagctcac gagcaaattt ctgcgccact accgcatcgc caagcatgac cggaataatg
    21661 gcgtgatcgg ctcccgccag ggtaaagccc gccgccgaca tttgctcacg gaactgacgc
    21721 gcgttcgccc acaaacggtc acgtagctcg ctgcccgctt caaccatctc cagcactttg
    21781 atggaagcgg cgacaatcgc tggtgccagc gagttggaga acaggtacgg acgagaacgc
    21841 tggcgtagcc actcaaccac ttctttgcgc gccgcggtat aaccaccaga agccccgccc
    21901 agcgctttac caagcgtacc ggtgataata tcgacccggc ccatcacatc gcagtattca
    21961 tgggaaccac gaccgttttc accgacaaaa ccgaccgcgt gggagtcgtc taccatcacc
    22021 agggcatcgt atttatctgc cagattgcaa acgcccttca gattggcaat cacgccgtcc
    22081 atcgagaaca caccatcggt ggcaatcagc acatgacgcg caccggcttc acgcgcttct
    22141 ttcagacgag cttcaagctc ctgcatatcg ttgttggcat agcgatagcg tttagcttta
    22201 cacagacgca caccatcaat aatagacgcg tggttcagtg cgtcggagat aatggcgtct
    22261 tccgcaccca gcagtgtttc aaacaggcca ccgttagcat caaagcagga agagtagaga
    22321 atcgcatctt ccatccccag gaatgcagcc agcttctgct caagctcttt gtggctgtcc
    22381 tgagtgccac aaataaaacg caccgaagcc atgccgaaac catgagaatc cattcccgct
    22441 tttgctgccg caatcagttc cgggtggttc gccagcccca ggtagttatt ggcacaaaag
    22501 ttaatgacgt ggctaccatc cgccacagtg atatccgctt gttgagcgga tgtgataatg
    22561 cgctcttctt taaacaatcc ttccgcacga gcggtttcca gatcgttggc taactgctga
    22621 taaaaatctc cacgcatcgc gattctccag actgggcaaa tttcagcaca tattaccgaa
    22681 agccataggt tgatacgaga tgaagcattt gtacttgtca aaaaataagc ataaatcacg
    22741 ctcaggcata ccactttcgg tgaatggctg tagccagcgc cgtgtagtga tatgatagaa
    22801 gtattcgtgt ctgagattgt ctctgactcc acaattcgaa ggttacagtt atgatcatcg
    22861 ttaccggcgg cgcgggcttt atcggcagca acatcgttaa agccctgaat gacaaaggca
    22921 tcaccgatat tctggtggtg gacaacctga aagacggcac caagtttgtg aacctggtgg
    22981 acctgaatat cgcagactat atggataagg aagacttcct gatccagatt atggctggcg
    23041 aagagttcgg cgatgtcgaa gcgattttcc acgaaggcgc gtgctcttcc accaccgagt
    23101 gggacggcaa gtatatgatg gataacaact atcaatactc caaggagctg ctgcactact
    23161 gcctggagcg tgaaatcccg ttcctgtacg cttcatccgc agccacttac ggcggtcgca
    23221 cttccgactt tattgaatcc cgcgagtacg aaaaaccgtt gaacgtctac ggttactcga
    23281 aattcctgtt tgatgaatat gttcgtcaaa ttctgccgga agcaaactca cagattgttg
    23341 gcttccgtta tttcaacgtt tatggaccgc gtgaaggcca taaaggcagc atggcgagcg
    23401 tcgctttcca tctcaacacc cagcttaata acggtgaatc accgaagctg ttcgaaggta
    23461 gcgagaactt taaacgcgac ttcgtctatg ttggcgacgt ggcagatgta aacctgtggt
    23521 tcctggaaaa tggcgtttcc ggcatcttca acctcggtac tggtcgtgcg gaatccttcc
    23581 aggcggtagc cgatgcaacg cttgcttatc acaagaaagg ccagatcgaa tacattccgt
    23641 tcccggataa actgaaaggc cgctatcagg cattcacgca ggcagatctg acgaatctgc
    23701 gcgcggcggg ttatgacaaa ccgttcaaaa ccgttgccga aggcgtaacg gaatacatgg
    23761 cctggctgaa tcgcgacatc aacgtaaatt cacaaaatca ttcgagcggt atcaaggcag
    23821 caactaagtg aatctccggg agcttacaaa agtaagtgac cggagtgaac gcaggcagcc
    23881 gccgcagaga cagcttgaag gatgaagtga atgaaaatat tggtgatcgg cccgtcatgg
    23941 gtgggcgaca tgatgatgtc gcaaagtctc tatcgcacgc tccaggcgcg ctatccccag
    24001 gcgataatcg acgtgatggc accggcatgg tgccgtccat tattatcgcg gatgccggaa
    24061 gttaacgaag ccattcctat gccgcttggt cacggagcgc tggaaattgg cgaacgccgc
    24121 aagctgggtc atagcctgcg cgaaaaacgt tacgaccgcg cctacgtttt acccaactcc
    24181 ttcaaatccg cattagtgcc tttcttcgcg ggtattcctc atcgcaccgg ctggcgcggc
    24241 gaaatgcgct acggtttact caacgatgtg cgtgtgctgg ataaagaagc ctggccgctg
    24301 atggtggaac gctatgtggc gctggcctat gacaaaggta ttatgcgtac cgcacaagat
    24361 ctgccgcagc cattgttatg gccgcagttg caggtgagcg aaggtgaaaa atcatatacc
    24421 tgtaatcaat tttcgctttc atcagaacgt ccaatgattg gtttttgccc gggtgcggag
    24481 tttggtccgg caaaacgctg gccacactac cactatgcgg aactggcaaa gcaactgatt
    24541 gatgaaggtt atcaagtggt tctgtttggc tcggcgaaag atcatgaagc gggcaatgag
    24601 attcttgccg ctttaaatac cgagcagcag gcatggtgcc ggaacctggc gggggaaaca
    24661 cagcttgatc aagcggttat cctgattgca gcctgtaaag ccattgtcac taacgattct
    24721 ggcctgatgc acgttgcggc ggcgctcaat cgtccgctgg ttgccctgta tggtccgagt
    24781 agcccggact tcacaccgcc gctatcccat aaagcgcgcg tgatccgcct gattaccggc
    24841 tatcacaaag tacgcaaagg cgacgccgca gaaggttatc accagagctt gatcgacatt
    24901 actccccagc gcgtgctgga agaactcaac tctctattgt tacaagagga agcctgacgg
    24961 atgcgggttt tgatcgttaa aacatcgtcg atgggcgatg ttctccatac gttgcccgca
    25021 ctcactgatg cccagcaggc aatcccaggg attaagtttg actgggtggt ggaagaaggg
    25081 ttcgcacaga ttccttcctg gcacgccgcc gttgagcgag ttattcctgt ggcaatacgt
    25141 cgctggcgta aagcctggtt ctcggccccc ataaaagctg aacgcaaagc gtttcgtgaa
    25201 gcgctacaag cagagaacta tgacgcagtt atcgatgctc aggggctggt aaaaagcgcg
    25261 gcgctggtga cgcgtctggc gcatggcgta aagcatggaa tggactggca aaccgctcgc
    25321 gaacctttag ccagcctgtt ttacaatcgt aaacatcata ttgcaaaaca gcagcacgcc
    25381 gtagaacgca tccgcgaact ttttgccaaa agtctgggct atagcaaacc gcaaacccag
    25441 ggcgattatg ctatcgcaca gcattttctg acgaacctgc ctacagatgc tggcgaatat
    25501 gccgtatttc ttcatgcgac gacccgtgat gataaacact ggccggaaga acactggcga
    25561 gaattgattg gtttactggc agattcaggg attcgcatta aacttccgtg gggtgcgccg
    25621 catgaggaaa aacgggcgaa acgactggcg gaaggatttg cttatgttga agtattgccg
    25681 aagatgagtc tggaaggtgt tgcccgtgtg ctggccggag cgaaattcgt ggtatcggta
    25741 gacactgggt taagtcattt aactgcagca ctggatcgac cgaatatcac ggtttatgga
    25801 ccaaccgatc cgggattaat tggcggatat gggaagaatc aggtggtttg tagggcacca
    25861 gataaagatc ttgctcatct gactgcagaa acggtattta ataaaatcaa tt
//
LOCUS       DAPOAV010000064        25899 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.064, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000064 DAPOAV010000000
VERSION     DAPOAV010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25899
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.064"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..290)
                     /gene="tuf"
                     /locus_tag="RN951_002986"
     CDS             complement(<1..290)
                     /gene="tuf"
                     /locus_tag="RN951_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDX2527957.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     RAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAA"
     gene            complement(361..2475)
                     /gene="fusA"
                     /locus_tag="RN951_002987"
     CDS             complement(361..2475)
                     /gene="fusA"
                     /locus_tag="RN951_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020455498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDX2527958.1"
                     /translation="MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVH
                     DGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERS
                     MRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKT
                     RLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMVELANEW
                     HQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNNEIILVTCGSAFKNKGVQ
                     AMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLT
                     FFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVT
                     TGDTLCDPDAPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTD
                     EESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQ
                     SGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKAGPL
                     AGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETP
                     EENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTM
                     EFLKYDEAPSNVAQAVIEARGK"
     gene            complement(2572..3042)
                     /gene="rpsG"
                     /locus_tag="RN951_002988"
     CDS             complement(2572..3042)
                     /gene="rpsG"
                     /locus_tag="RN951_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015873274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HDX2527959.1"
                     /translation="MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVY
                     SALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMR
                     WIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRW"
     gene            complement(3139..3513)
                     /gene="rpsL"
                     /locus_tag="RN951_002989"
     CDS             complement(3139..3513)
                     /gene="rpsL"
                     /locus_tag="RN951_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005306278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HDX2527960.1"
                     /translation="MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKK
                     PNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGAL
                     DCSGVKDRKQARSKYGVKRPKA"
     gene            complement(3639..3926)
                     /gene="tusB"
                     /locus_tag="RN951_002990"
     CDS             complement(3639..3926)
                     /gene="tusB"
                     /locus_tag="RN951_002990"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusB"
                     /protein_id="HDX2527961.1"
                     /translation="MLHTLHRSPWLTDFAALLRLLSEGDELLLLQDGVTAAVDGNRYL
                     ESLRNAPIKVYALNEDLIARGLTGQISNDIILIDYTDFVRLTVKHPSQMAW"
     gene            complement(3934..4293)
                     /gene="tusC"
                     /locus_tag="RN951_002991"
     CDS             complement(3934..4293)
                     /gene="tusC"
                     /locus_tag="RN951_002991"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusC"
                     /protein_id="HDX2527962.1"
                     /translation="MKRIAFVFSTAPHGTAAGREGLDALLATSALTDDLAVFFIADGV
                     FQLLPGQKPDAVLARDYIATFKLLGLYDIEQCWVCAASLRERGLDPQTPFVVEATPLE
                     ADALRRELANYDVILRF"
     gene            complement(4293..4679)
                     /gene="tusD"
                     /locus_tag="RN951_002992"
     CDS             complement(4293..4679)
                     /gene="tusD"
                     /locus_tag="RN951_002992"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusD"
                     /protein_id="HDX2527963.1"
                     /translation="MRFAIVVTGPAYGTQQASSAFQFAQALIADGHELSSVFFYREGV
                     YNANQLTSPASDEFDLVRAWQQLNAQHGVALNICVAAALRRGVVDETEAGRLGLASSN
                     LQQGFTLSGLGALAEASLTCDRVVQF"
     gene            complement(4679..5401)
                     /locus_tag="RN951_002993"
     CDS             complement(4679..5401)
                     /locus_tag="RN951_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDX2527964.1"
                     /translation="MSRSLLTNETSELDLLDQRPFDQTDFDILKSYEAVVDGLAMLIG
                     SHCEIVLHSLQDLKCSAIRIANGEHTGRKIGSPITDLALRMLHDMTGADSSVSKCYFT
                     RAKSGVLMKSLTIAIRNREQRVIGLLCINMNLDVPFSQIMSTFVPPETPDVGSSVNFA
                     SSVEDLVTQTLEFTIEEVNADRNVSNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNI
                     SKHTVYLYIRQFKSGDFQGQDK"
     gene            complement(5568..6380)
                     /gene="fkpA"
                     /locus_tag="RN951_002994"
     CDS             complement(5568..6380)
                     /gene="fkpA"
                     /locus_tag="RN951_002994"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDX2527965.1"
                     /translation="MKSLFKVTLLATTMAVALHAPITFAAEAAKPATAADSKAAFKND
                     DQKSAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAFADKSKLSDQEIEQTL
                     QAFEARVKSSAQAKMEKDAADNEAKGKEYREKFAKEKGVKTSSTGLVYQVVEAGKGEA
                     PKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGLKNIKKGGKIKLV
                     IPPELAYGKAGVPGIPPNSTLVFDVELLDVKPAPKADAKPEADAKAADSAKK"
     gene            6601..6819
                     /locus_tag="RN951_002995"
     CDS             6601..6819
                     /locus_tag="RN951_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein SlyX"
                     /protein_id="HDX2527966.1"
                     /translation="MQDLSLEARLAELESRLAFQEITIEELNVTVTAHEMEMAKLRDH
                     LRLLTEKLKASQPSNIASQAEETPPPHY"
     gene            complement(6868..7458)
                     /gene="slyD"
                     /locus_tag="RN951_002996"
     CDS             complement(6868..7458)
                     /gene="slyD"
                     /locus_tag="RN951_002996"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDX2527967.1"
                     /translation="MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLISG
                     LETALEGHEVGDKFDVAVGANDAYGQYDENLVQRVPKDVFMGVDELQVGMRFLAETDQ
                     GPVPVEITAVEDDHVVVDGNHMLAGQNLKFNVEVVAIREATEEELAHGHVHGAHDHHH
                     DHDHDGCCGGHGHDHGHEHGGEGCCGGKGNGGCGCH"
     gene            complement(7553..7753)
                     /locus_tag="RN951_002997"
     CDS             complement(7553..7753)
                     /locus_tag="RN951_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheV family putative metal-binding protein"
                     /protein_id="HDX2527968.1"
                     /translation="MAIRKRFIAGAKCPACQAQDSMAMWRENNIDIVECVKCGHQMRE
                     ADKEARDHVRKDEQVIGIFHPD"
     gene            complement(7763..9568)
                     /gene="kefB"
                     /locus_tag="RN951_002998"
     CDS             complement(7763..9568)
                     /gene="kefB"
                     /locus_tag="RN951_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefB"
                     /protein_id="HDX2527969.1"
                     /translation="MEGSDFLLAGVLFLFAAVAAVPLASRLGIGAVLGYLLAGIAIGP
                     WGLGFISDVDEILHFSELGVVFLMFIIGLELNPSKLWQLRRSIFGVGAAQVLLSAALL
                     AGLLMLTDFAWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAV
                     IPALALVPLLAGSADEHFDWMKVGMKVLAFVGMLIGGRYLLRPVFRFIAASGVREVFT
                     AATLLLVLGSALFMDALGLSMALGTFIAGVLLAESEYRHELETAIDPFKGLLLGLFFI
                     SVGMSLNLGVLYTHLLWVVISVVVLVAVKILVLYLLARLYGVRSSERMQFAGVLSQGG
                     EFAFVLLSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKLVDKWLSRQFNGPEEEDE
                     KPWVNDDKPQVIVVGFGRFGQVIGRLLMANKMRITVLERDISAVNLMRKYGYKVYYGD
                     ATQVDLLRSAGAEAAESIVITCNEPEDTMKLVEICQQHFPHLHILARARGRVEAHELL
                     QAGVTQFSRETFSSALELGRKTLVTLGMHPHQAQRAQLHFRRLDMRMLRELIPMHADT
                     VQISRAREARRELEEIFQREMQQERRQLDGWDEFE"
     gene            complement(9568..10119)
                     /gene="kefG"
                     /locus_tag="RN951_002999"
     CDS             complement(9568..10119)
                     /gene="kefG"
                     /locus_tag="RN951_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312229.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     ancillary protein KefG"
                     /protein_id="HDX2527970.1"
                     /translation="MSQPAKVLLLYAHPESQDSVANRVLLKPATQLSNVTVHDLYAHY
                     PDFFIDIPREQALLREHEVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAG
                     KYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELAAGMCRMHWLSPIIIYWARRQSA
                     QELASHARAYGDWLANPLSPGGR"
     gene            10250..12163
                     /locus_tag="RN951_003000"
     CDS             10250..12163
                     /locus_tag="RN951_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX2527971.1"
                     /translation="MIVFSSLQIRRGVRVLLDNATATINPGQKVGLVGKNGCGKSTLL
                     ALLKNEISADGGSYTFPGSWQLAWVNQETPALPQAALEYVIDGDREYRQLEAQLHDAN
                     ERNDGHAIATIHGKLDAIDAWSIRSRAASLLHGLGFSNEQLERPVSDFSGGWRMRLNL
                     AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYQGTLILISHDRDFLDPIVDKIIH
                     IEQQSMFEYTGNYSSFEVQRATRLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQA
                     QSRIKMLERMELIAPAHVDNPFRFSFRAPESLPNPLLKMEKVSAGYGDRIILDSIKLN
                     LVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAKGIKLGYFAQHQLEYLRADE
                     SPIQHLARLAPQELEQKLRDYLGGFGFQGDKVTEETRRFSGGEKARLVLALIVWQRPN
                     LLLLDEPTNHLDLDMRQALTEALIEFEGALVVVSHDRHLLRSTTDDLYLVHDRKVEPF
                     DGDLEDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPLRKEIAR
                     LEKEMEKLNAQLAQAEEKLGDSELYDQSRKAELTACLQQQASAKSGLEECEMAWLEAQ
                     EQLEQMLLEGQSN"
     gene            12163..13185
                     /locus_tag="RN951_003001"
     CDS             12163..13185
                     /locus_tag="RN951_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDX2527972.1"
                     /translation="MAQITTTDANEFSSSAEFIPMRGFSNCHLQTMLPRLFRRQVKFT
                     PYWQRLELPDGDFVDLAWSENPAQAQHKPRLVVFHGLEGSLNSPYAHGLVEAAQKRGW
                     LGVVMHFRGCSGEPNRMHRIYHSGETEDASWFLRWLQREFGHAPTAAVGYSLGGNMLA
                     CLLAKEGNDLPVDAAVIVSAPFMLEACSYHMEKGFSRVYQRYLLNLLKANAARKLAAY
                     PGTLPINLAQLKSVRRIREFDDLITARIHGYADAIDYYRQCSAMPMLNRIAKPTLIIH
                     AKDDPFMDHQVIPKPESLPPQVEYQLTEHGGHVGFIGGTLLHPQMWLESRIPDWLTTY
                     LEAKSC"
     gene            13179..13397
                     /locus_tag="RN951_003002"
     CDS             13179..13397
                     /locus_tag="RN951_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheU family protein"
                     /protein_id="HDX2527973.1"
                     /translation="MLIPWQDLSPETLENLIESFVLREGTDYGEHERTLEQKVADVKR
                     QLQCGEAVLVWSELHETVNIMPRSQFRE"
     gene            13451..14320
                     /locus_tag="RN951_003003"
     CDS             13451..14320
                     /locus_tag="RN951_003003"
                     /EC_number="2.7.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HDX2527974.1"
                     /translation="MSAKHPVIAVTGSSGAGTTTTSLAFRKIFAQLNLHAAEVEGDSF
                     HRYTRPEMDMAIRKARDAGRHISYFGPEANDFGLLEQTFIEYGQSGKGKSRKYLHTYD
                     EAVPWNQVPGTFTPWQPLPEPTDVLFYEGLHGGVVTPQHNVAQHVDLLVGVVPIVNLE
                     WIQKLIRDTSERGHSREAVMDSVVRSMEDYINYITPQFSRTHLNFQRVPTVDTSNPFA
                     AKGIPSLDESFVVIHFRNLEGIDFPWLLAMLQGSFISHINTLVVPGGKMGLAMELIML
                     PLVQRLMEGKKIE"
     gene            complement(14375..14779)
                     /locus_tag="RN951_003004"
     CDS             complement(14375..14779)
                     /locus_tag="RN951_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HDX2527975.1"
                     /translation="MQARVKWVEGLTFLGESASGHQILMDGNSGDKAPSPMEMVLMAA
                     GGCSAIDVVSILQKGRQDVVDCEVKLTSERREEAPRLFTHINLHFIVTGRDLKDAAVA
                     RAVDLSAEKYCSVALMLEKAVNITHSYEVVAA"
     gene            15081..15713
                     /gene="crp"
                     /locus_tag="RN951_003005"
     CDS             15081..15713
                     /gene="crp"
                     /locus_tag="RN951_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cAMP-activated global transcriptional regulator
                     CRP"
                     /protein_id="HDX2527976.1"
                     /translation="MVLGKTQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIV
                     KGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKK
                     FRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
                     PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR"
     gene            15764..17854
                     /locus_tag="RN951_003006"
     CDS             15764..17854
                     /locus_tag="RN951_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312236.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDX2527977.1"
                     /translation="MWRRLIYHPDINYALRQTLVLCLPVAVGLMLGELRFGLLFSLVP
                     ACCNIAGLDTPHKRFFKRLIIGASLFATCSLLTQLLLAKDVPLPFLLTGLTLVLGVTA
                     ELGPLHAKLLPASLLAAIFTLSLAGYMPVWEPLLIYALGTLWYGLFNWFWFWIWREQP
                     LRESLSLLYRELADYCEAKYSLLTQHTDPEKALPPLLVRQQKAVDLITQCYQQMHMLS
                     AQNNTDYKRMLRIFQEALDLQEHISVSLHQPEEVQKLVERSHAEEVIRWNAQTVAARL
                     RVLADDILYHRLPTRFTMEKQIGALEKIARQHPDNPVGQFCYWHFSRIARVLRTQKPL
                     YARDLLADKQRRMPLLPALKSYLSLKSPALRNAGRLSVMLSVASLMGTALHLPKSYWI
                     LMTVLLVTQNGYGATRLRIVNRSVGTVVGLIIAGVALHFKIPEGYTLTLMLITTLASY
                     LILRKNYGWATVGFTITAVYTLQLLWLNGEQYILPRLIDTIIGCLIAFGGTVWLWPQW
                     QSGLLRKNAHDALEAYQEAIRLILSEDPQPTPLAWQRMRVNQAHNTLYNSLNQAMQEP
                     AFNSHYLADMKLWVTHSQFIVEHINAMTTLAREHRALPPELAQEYLQSCEIAIQRCQQ
                     RLEYDEPGSSGDANIMDAPEMQPHEGAAGTLEQHLQRVIGHLNTMHTISSMAWRQRPH
                     HGIWLSRKLRDSKA"
     gene            complement(17921..19141)
                     /gene="argD/dapC"
                     /locus_tag="RN951_003007"
     CDS             complement(17921..19141)
                     /gene="argD/dapC"
                     /locus_tag="RN951_003007"
                     /EC_number="2.6.1.11"
                     /EC_number="2.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     acetylornithine/succinyldiaminopimelate transaminase"
                     /protein_id="HDX2527978.1"
                     /translation="MAIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEY
                     VDFAGGIAVTALGHCHPALVNALKTQGETLWHISNVFTNEPALRLGRKLIEATFAERV
                     VFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDG
                     FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQ
                     HQALLVFDEVQCGMGRTGDLFAYMHYGVTPDILTSAKALGGGFPISAMLTTAEIASAF
                     HPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVDHLQKIDQQYDVFSD
                     IRGMGLLIGAELKPQYKGRARDFLYAGAEAGVMVLNAGPDVMRFAPSLVVEDADIDEG
                     MQRFAHAVAKVVGA"
     gene            complement(19227..19790)
                     /gene="pabA"
                     /locus_tag="RN951_003008"
     CDS             complement(19227..19790)
                     /gene="pabA"
                     /locus_tag="RN951_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 2"
                     /protein_id="HDX2527979.1"
                     /translation="MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDALKP
                     QKIVISPGPCTPDEAGISLDVIRHYAGRLPILGVCLGHQAMAQAFGGKVVRAAKVMHG
                     KTSPITHNGEGVFRGLANPLTVTRYHSLVVEPDSLPACFDVTAWSETREIMGIRHRQW
                     DLEGVQFHPESILSEQGHQLLANFLHR"
     gene            complement(19822..20424)
                     /locus_tag="RN951_003009"
     CDS             complement(19822..20424)
                     /locus_tag="RN951_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative adenosine monophosphate-protein
                     transferase Fic"
                     /protein_id="HDX2527980.1"
                     /translation="MSDKFGEGRDPYLYPGLDIMRNRLNIRQQQRLEQAAYEMTALRA
                     ATIELGPLVRGLPHLRTIHRQLYQDIFDWAGQLREVDIYQGDTPFCHFAYIEKEGNAL
                     MQDLEEEGYLVGLEKAKFVERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQL
                     SWQGIEKEAWNQANQSGAMGDLTALQMIFSKVVSEAGESE"
     gene            complement(20414..20581)
                     /locus_tag="RN951_003010"
     CDS             complement(20414..20581)
                     /locus_tag="RN951_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfG family protein"
                     /protein_id="HDX2527981.1"
                     /translation="MKKLTDKQKSRLWELQRNRNFQASRRLEGVEMPLVTLTAAEALA
                     RLEELRSHYER"
     gene            complement(20686..21258)
                     /gene="ppiA"
                     /locus_tag="RN951_003011"
                     /gene_synonym="rotA"
     CDS             complement(20686..21258)
                     /gene="ppiA"
                     /locus_tag="RN951_003011"
                     /gene_synonym="rotA"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase A"
                     /protein_id="HDX2527982.1"
                     /translation="MFKSTLAAMAAVFALSALSPAAMAAKGDPHVLLTTSAGNIELEL
                     DKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQKKPNPPIKNEAD
                     NGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVAD
                     KISQVPTHDVGPYQNVPSKPVVILSAKVLP"
     gene            21529..22710
                     /gene="tsgA"
                     /locus_tag="RN951_003012"
     CDS             21529..22710
                     /gene="tsgA"
                     /locus_tag="RN951_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter TsgA"
                     /protein_id="HDX2527983.1"
                     /translation="MTNSNRIKLTWISFLSYALTGALVIVTGMVMGNIADYFNLPVSS
                     MSNTFTFLNAGILISIFLNAWLMEIVPLKTQLRFGFLLMVLAVAGLMFSHSLALFSAA
                     MFILGVVSGITMSIGTFLVTQMYEGRQRGSRLLFTDSFFSMAGMIFPMIAAFLLARSI
                     EWYWVYACIGLVYVAIFILTFGCEFPALGKHAPKTDAPVEKEKWGIGVLFLSVAALCY
                     ILGQLGFISWVPEYAKGLGMSLNDAGTLVSNFWMSYMVGMWAFSFILRFFDLQRILTV
                     LAGLAAILMYVFNTGTPAHMAWSILALGFFSSAIYTTIITLGSQQTKVPSPKLVNFVL
                     TCGTIGTMLTFVVTGPIVEHSGPQAALLTANGLYAVVFVMCFLLGFVSRHRQHNTLTS
                     H"
     gene            22972..25515
                     /gene="nirB"
                     /locus_tag="RN951_003013"
     CDS             22972..25515
                     /gene="nirB"
                     /locus_tag="RN951_003013"
                     /EC_number="1.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-nitrite reductase large subunit"
                     /protein_id="HDX2527984.1"
                     /translation="MSKVRLAIIGNGMVGHRFIEDLLDKSDAANFDITVFCEEPRIAY
                     DRVHLSSYFSHHTAEELSLVREGFYEKHGIKVLVGERAITINRQEKVIHSSAGRTVFY
                     DKLIMATGSYPWIPPIKGSDTQDCFVYRTIEDLNAIESCARRSKRGAVVGGGLLGLEA
                     AGALKNLGIETHVIEFAPMLMAEQLDQMGGEQLRRKIESMGVRVHTSKNTLEIVQEGV
                     EARKTMRFADGSELEVDFIVFSTGIRPRDKLATQCGLDVAPRGGIVINDSCQTSDPDI
                     YAIGECASWNNRVFGLVAPGYKMAQVAVDHILGSENAFEGADLSAKLKLLGVDVGGIG
                     DAHGRTPGARSYVYLDESKEIYKRLIVSEDNKTLLGAVLVGDTSDYGNLLQLVLNAIE
                     LPENPDSLILPAHSGSGKPSIGVDKLPDSAQICSCFDVTKGDLIAAINKGCHTVAALK
                     AETKAGTGCGGCIPLVTQVLNAELAKQGIEVNNNLCEHFAYSRQELFHLIRVEGIKTF
                     EELLAKHGKGYGCEVCKPTVGSLLASCWNEYILKPEHTPLQDSNDNFLANIQKDGTYS
                     VIPRSPGGEITPEGLMAVGRIAREFNLYTKITGSQRLAMFGAQKDDLPEIWRQLIEAG
                     FETGHAYAKALRMAKTCVGSTWCRYGVGDSVGLGVELENRYKGIRTPHKMKFGVSGCT
                     RECSEAQGKDVGIIATEKGWNLYVCGNGGMKPRHADLLAADIDRETLIKYLDRFMMFY
                     IRTADKLTRTAPWLENLEGGIDYLKAVIIDDKLGLNAHLEEEMARLREAVLCEWTETV
                     NTPSAQTRFKHFINSDKRDPNVQMVPEREQHRPATPYERIPVTLVEDNA"
     gene            25512..25838
                     /gene="nirD"
                     /locus_tag="RN951_003014"
     CDS             25512..25838
                     /gene="nirD"
                     /locus_tag="RN951_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase small subunit NirD"
                     /protein_id="HDX2527985.1"
                     /translation="MSQWKDICKIDDILPETGVCALLGDEQVAIFRPYHSDQVFAISN
                     IDPFFESSVLSRGLIAEHQGELWVASPLKKQRFRLSDGLCMEDEQFSVKHYEARVKDG
                     VVQLRG"
BASE COUNT         6302 a         7000 c         6497 g         6100 t
ORIGIN      
        1 gcagcaccgg tgatcatgtt tttaacatag tcggcgtgcc ccgggcagtc tacgtgtgcg
       61 tagtgacggg tcggggtgtc gtattcaacg tgagaagtgt tgatggtgat accacgagct
      121 ttttcttccg gcgcgttatc gatctggtcg aatgcacgag cagcaccgcc gtaggtttta
      181 gccagtacgg tggtgattgc agcggtcaga gtagttttac cgtggtcaac gtggccgata
      241 gtaccaacgt taacgtgcgg ttttgtacgt tcaaattttt ctttagacac ggctatattc
      301 cttactatag tgctctcccc ttcaggagag agcacgggac tttggtatta acccttaggc
      361 ttatttacca cgggcttcaa ttacggcctg agcaacgtta ctcggcgctt catcatactt
      421 caggaattcc atagtgtatg atgcacgacc tttggtcaga gaacgcagct gagttgcgta
      481 tccgaacatt tcagacagcg gtacttcagc gtggatctta acgccagtaa cttcagattc
      541 ctgacctttg agcataccac gacgacggct caagtcaccg ataacgtcac cggtgttctc
      601 ttccggagtt tctacttcaa ccttcatgat cggctcaagc agaactggtt tcgctttctt
      661 aaagccttct ttaaaggcga tagaagcagc cagtttaaac gccagttcag aggagtcaac
      721 gtcatggtaa gaaccgaagt gcagacgaat acccatgtct actaccgggt agcctgccag
      781 cggacctgct ttcagctgtt cctggatacc tttatcaacg gccgggatgt attcgccagg
      841 gattacacca cctttaatgt cgttgatgaa ctcgtagcct ttcgggtttg aacccggctc
      901 cagcgggtac atgtcgataa caacatgacc atactgacca cgaccaccag actgtttcgc
      961 gtgtttacct tcaacatcgg taactttctg gcggatagtt tcacggtaag caacctgcgg
     1021 tttacctacg ttcgcttcaa cgttgaattc acgcttcata cggtcaacga tgatgtcgag
     1081 gtgcagttcg cccatacccg cgatgatggt ctggttagat tcttcgtcag tccatacacg
     1141 gaaagacggg tcttctttag ccagacggcc cagagccaga cccatttttt cctggtcagc
     1201 tttggttttc ggttcaactg cgatggagat taccggctca gggaattcca tacgttccag
     1261 aatgatcggc gcatccgggt cacacagggt gtcaccagtg gttacgtctt tcagaccgat
     1321 agcagcagcg atgtcgcccg cgcgaacttc tttgatctct tcacgtttgt tagcgtgcat
     1381 ctgaacgata cgaccgaaac gctcacgtgc agctttcacg gagttcagta cggtatcacc
     1441 agagttaacc acaccggagt aaacacggaa gaaggtcagg ttaccaacaa acgggtcggt
     1501 agcgattttg aacgccagtg cagagaacgg ctcgtcatca cttgcgtgac gttcagccgg
     1561 agtgtcttta ccgtcgtcca ggataccgtt gatcgcaggt acgtcaaccg gggatggcag
     1621 gtaatcaatt accgcatcca gcatcgcctg aacacctttg ttcttgaacg cagaaccaca
     1681 ggttaccagg atgatttcgt tgttcagaac gcgctgacgc agagcacctt tgatttctgc
     1741 ttcagtcagt tcttcaccac ccaggtattt ttccatcagc tcttcagaag cttcagctgc
     1801 ggattcgatc aggttctggt gccattcgtt agccagttca accatgtctg ccgggatatc
     1861 ttcgtattcg aaggttacgc cctggtcagc gtcgttccag ttgatagctt tcattttcac
     1921 caggtcaaca acaccggtga aatgttcttc agcaccaatc gccagctgca gcggaaccgg
     1981 gttcgcgccc agacgggttt tgatctggtt aacaactttc aggaagttcg cacccatgcg
     2041 gtccattttg ttaacgaacg caatgcgcgg aactttatat ttgtttgcct gacgccatac
     2101 ggtttcagac tgcggctgaa caccaccaac tgcgcagtaa accattaccg caccatcgag
     2161 aacacgcatg gaacgttcta cttcgattgt gaagtcaacg tgccccgggg tgtcgatgat
     2221 gttgatgcga tgcggctcat actgcttagc cataccagac cagaatgcag tagtcgcagc
     2281 ggaagtgatg gtaataccac gttcctgctc ctgctccatc cagtccatgg ttgcagcgcc
     2341 gtcatgaact tcaccgattt tatggtttac accggtgtag aacagaatac gttcggtagt
     2401 agtggtttta ccggcgtcga tgtgcgcact gataccgatg ttacggtagc gtgcgatggg
     2461 tgttgtacga gccatttgtt tcctcgttta tcttttaggc gttcaattta agtagcccaa
     2521 agcgggctgc ttactggaag cgcccgcctg gtgactaaaa ctccgaaggg attaccaacg
     2581 gtagtgtgcg aacgccttgt tggcttcggc catacggtga acgtcttcac gtttcttaac
     2641 tgcagtacct ttgttttctg cagcatcaga aagttcgttc gccaggcgca gagccatgga
     2701 tttatcaccg cgtttacgag cagcttcaac gatccaacgc attgccagag cattacgacg
     2761 aaccggacgg acttcaactg gtacctgata agtagaacca ccaacgcggc gagacttaac
     2821 ttctacagtc gggcgcacgt tttcgagagc tacttcgaat gcttccagtt cagatttacc
     2881 agagcgctga gccagggtct ccagcgcgct gtatacgata gattcagcag tagatttttt
     2941 accatctacc atcaggatat ttacaaattt agccagcagt tctgatccga acttcggatc
     3001 cggcagaatt ttacgctgac caatgacgcg acgacgtggc atggaaatac tccgttgtta
     3061 attcaggatt gtccaaaact ctacgagttt agtttgacat ttaagttaaa acgtttggcc
     3121 ttacttaacg gagaaccatt aagccttagg acgcttcacg ccatacttgg aacgagcctg
     3181 cttacggtct ttaacgccgg agcagtcaag cgcaccacgt acggtgtggt aacgaacacc
     3241 cgggaggtct ttaacacgac cgccacggat caggatcacg gagtgctcct gcaggttgtg
     3301 accttcacca ccgatgtagg aagtcacttc gaaaccgtta gtcagacgaa cacggcatac
     3361 tttacgcagc gcggagttcg gttttttagg agtggtagta tatacacgag tacatacgcc
     3421 acgtttttgc gggcatgctt ccagcgcagg cacgttgctt ttcgcaactt tgcgagcacg
     3481 tggtttgcgt accagctggt taactgttgc cattaaatag ctcctggttt tagcttttgc
     3541 ttcgtaaaca cgtaataaaa cgtcctcaca caatatgagg acgccgaatt ttagggcgat
     3601 gccgaaaagg tgtcaagaaa tatacaacga tcccgccatc accaggccat ctggctgggg
     3661 tgcttaaccg taagtctgac gaaatcagta tagtcaatga gaatgatgtc gttcgaaatt
     3721 tgaccagtca aaccgcgggc aataaggtct tcgttcaggg catagacctt aatgggggca
     3781 ttacgcagac tttcaaggta gcggttaccg tcaactgcgg cagttacgcc atcttgcaat
     3841 aatagcagtt cgtctccttc actgagcaga cgcagcagcg cagcaaaatc cgtcagccag
     3901 ggtgagcgat gtaatgtgtg cagcataaac gcctcaaaac ctcaaaataa catcgtagtt
     3961 ggcgagttcg cggcgtaagg catctgcttc gagcggcgtg gcttcgacaa caaagggtgt
     4021 ctgcggatct aacccgcgtt cgcgcagtga agccgcacaa acccagcact gttcaatgtc
     4081 gtacagaccc aacaatttaa aagtggcaat gtaatcacgc gccagcactg catcgggctt
     4141 ttgtcctggc agcagctgaa aaacgccatc agctataaag aagacagcca gatcgtcagt
     4201 taatgcggaa gttgccagta aagcatctaa accttcccgg cctgcggctg taccatgagg
     4261 tgcagtagaa aaaacaaacg caattcgttt catcagaact gtaccaccct gtcacaggtc
     4321 agcgaggctt ccgccagcgc cccaagtccg cttaaggtaa atccctgctg aaggtttgac
     4381 gaagccagcc ccagtcttcc ggcctccgtt tcatcaacaa cgccacggcg taatgctgcc
     4441 gctacgcaga tattcagcgc cacaccatgt tgcgcattca gttgttgcca ggcccgtacg
     4501 aggtcaaatt cgtcacttgc cggagaggtc aattggttag cgttatagac cccttcccga
     4561 tagaaaaaga cgctgcttaa ctcatggcca tctgctatca gcgcctgcgc aaactgaaaa
     4621 gcactactcg cctgttgcgt accgtatgct ggcccggtca ccacgatggc aaaacgcatt
     4681 acttatcttg cccctggaaa tcaccgctct tgaactggcg gatgtagaga tagacagtgt
     4741 gtttggagat gttcaggcgg tcagcaacct ggttgatcgc atctttaata tcgaagatcc
     4801 ctttctcgta gagattcagc acgatctgac gatttttggc gttattagaa acattgcgat
     4861 cggcattcac ttcttcgatg gtgaactcca gcgtttgggt aaccagatct tcaacagaag
     4921 aggcaaagtt gacgcttgaa ccgacatccg gggtttctgg cggcacaaag gtgctcataa
     4981 tctgcgagaa gggaacatca agattcatat tgatgcacag cagaccaatt acacgctgtt
     5041 cgcggttacg aatcgcgata gtcagggact tcattaatac gccgcttttg gcgcgagtaa
     5101 agtagcattt agaaacgctg ctatccgctc ccgtcatatc gtgcagcata cgtagcgcca
     5161 ggtcagtaat tggcgaacca atcttccggc ctgtatgttc accgttagca atgcgaatgg
     5221 ctgaacattt tagatcctgc aaagagtgca aaacgatttc acagtgggag ccaataagca
     5281 tcgctaaccc gtccaccacc gcttcgtagg atttcagaat atcaaaatcg gtctggtcga
     5341 aaggacgttg atccagtaaa tccaactcac tggtttcgtt ggttaaaagc gacctggaca
     5401 tgaaaaaaaa cactcctttt caggagcctg tcgttaactt ttcagggcag gctcattaat
     5461 gatgcgggta actaaattaa tacagcggag gttccgcttt ccagcactaa ttatatccgg
     5521 cctgtaataa aaaaaccgcc gcctggtcag gcggcggttc ttaatgctta ttttttagca
     5581 gaatctgcgg ctttcgcatc agcttccggc tttgcatcag ccttcggcgc tggtttcaca
     5641 tccagcagct ctacgtcaaa caccagggta gaattcggtg ggatccccgg aacacccgct
     5701 ttgccgtaag ccagttctgg tggaataacc agtttgatct taccgccttt cttgatgttc
     5761 ttcagacctt ctgtccaacc cgggataaca ccgtccagac ggaaagaaag cggttcacca
     5821 cgggtgtaag agttgtcgaa ctctttaccg tcgatcagcg tacctttgta gttcactaca
     5881 acagtatcgc tgtctttcgg tgcttcgcct ttaccggctt ctactacctg ataaaccaga
     5941 ccagttgaag aggttttcac acctttctct ttggcaaatt tctcgcggta ctctttacct
     6001 tttgcttcgt tatcagccgc gtctttttcc atcttcgcct gagcagaaga cttcacgcga
     6061 gcttcgaatg cttgtagagt ctgttcgatc tcttggtcgg agagtttgct cttatcagca
     6121 aatgcatcct gaacaccagc gatcagctga tctttatcca gtttgatgcc cagtttttct
     6181 tgttctttta gagagttttc catgtaacga cccagcgagg cacccagtgc ataagctgat
     6241 ttctgatcgt catttttgaa cgctgctttg ctgtcagcag ctgtagcagg ttttgcagct
     6301 tcagcagcaa aagtgattgg tgcatgcagg gcaacggcca ttgtggtcgc cagcagcgtt
     6361 actttaaaca gtgatttcat ccatatctcc aggatcgggg catctcaccc cagggttaac
     6421 tattatcaga agggtactat aaagcgttgt cgaacaaatc tacatacaga cacgccctat
     6481 tatcatctat tttcagactc tttttgttta aattagtttc gatgaccgcg aaatgagtgc
     6541 tgtctcgggc agcaaagtta agtagaatcc gcggcgacca ttcgacaaaa gaggtgaatc
     6601 atgcaggatt tatcattgga agcacgcctg gcagagctgg agagccgact ggcttttcag
     6661 gaaatcacca ttgaagaact gaacgtcacg gtgaccgctc atgaaatgga gatggcgaaa
     6721 ctgcgcgatc atctgcgtct gctgaccgag aagttaaaag ccagccagcc gtcgaacatc
     6781 gcgtcgcagg ctgaagaaac gccaccgcca cattattgag gcgtaaaaaa agcggggatt
     6841 ccccgctttt ttgtcacttt ttcggtatta gtggcaaccg caaccgccgt tgcctttacc
     6901 gccacagcag ccttcgccac cgtgttcatg accgtgatcg tggccatgac cgccgcagca
     6961 accgtcgtgg tcgtgatcgt ggtggtgatc gtgcgcgccg tgaacgtgac catgagccag
     7021 ttcttcttca gtcgcttcgc gaatcgccac aacttcaacg ttgaatttca ggttctgacc
     7081 ggccagcatg tggttaccat caaccacgac gtgatcgtct tcaaccgcag tgatttcaac
     7141 cggtaccgga ccctggtcgg tttcagccag gaaacgcata cctacctgca gttcatcaac
     7201 gcccataaat acgtctttag gaacacgttg caccaggttt tcgtcgtact gaccgtaagc
     7261 gtcgttcgcg ccaacagcga catcaaattt gtcgccaact tcatgacctt ccagcgccgt
     7321 ttccaggcca gagatcaggg aaccgtgacc atgcaggtag tccagcggcg cactcaccgg
     7381 agactcatca accaacacac cgtcttctgt acgtacctga taggccaggc tgaccaccag
     7441 gtcttttgct actttcatga tatctcctga gcatgggaag aatagtggcg cagattgtag
     7501 cggaattctg cagccgtgta ctcactagct taaaaaaact cggcgcatat cgctagtccg
     7561 gatgaaaaat cccgatcact tgctcatctt tgcgaacgtg atcgcgggct tctttgtctg
     7621 cttctcgcat ctgatgtccg cacttaacac attcaacaat atcaatatta ttttcgcgcc
     7681 acatcgccat tgaatcctgc gcctgacagg ccgggcattt tgcgcccgca ataaaacgtt
     7741 ttcggattgc catctttacc ctctactcaa attcatccca gccgtccagc tggcgtcgtt
     7801 cttgttgcat ttcacgctgg aaaatctctt ccagttcgcg tcgggcttcc ctggcgcgag
     7861 aaatttgtac ggtatcggca tgcattggga tgagctctcg cagcatccgc atatccaggc
     7921 ggcgaaaatg cagttgcgct cgctgtgcct gatgcggatg catgccaagc gtgaccagcg
     7981 tcttgcgccc cagctctaac gcactggaga atgtttcacg ggaaaactgc gtcacccctg
     8041 cctgtaataa ctcatgcgct tccacacgtc cgcgcgctcg cgcaagaata tgcaaatgcg
     8101 gaaagtgctg ttggcatatt tccaccagct tcatggtgtc ttccggctcg ttacaggtaa
     8161 tgacgataga ctcagcggcc tctgcacccg cagaacgtaa aagatcgacc tgcgtggcgt
     8221 cgccgtaata aactttgtag ccgtatttac gcatcaggtt aacggcgctg atatcccgct
     8281 ccagcacggt aatgcgcatt ttatttgcca tcagcaaacg accaatcacc tgaccaaaac
     8341 gcccgaagcc cacgacaatg acctggggtt tatcatcgtt gacccacggt ttttcgtctt
     8401 cttcttccgg tccgttaaac tggcgggata gccatttatc caccagcttc atcagcaacg
     8461 gcgtggtcat catggaaagc gtcaccgtca ccagcaacaa cgccatctgg tcgccctgga
     8521 ataagcgttg tgaagaagcg gtagaaagga ggacaaaggc aaactcacca ccctgactca
     8581 acacgccagc aaactgcatc cgctctgagc tacgcacgcc atacaatcgc gccagcagat
     8641 acagcacgag aattttcacc gccaccagca caaccacgct tatcactacc cacaacagat
     8701 gggtataaag caccccgagg ttgagtgaca tgccgacaga gataaagaac aaaccgagca
     8761 gcaagccttt gaagggatcg atagccgttt ccagttcatg gcgatattca ctttccgcca
     8821 gcagcacgcc cgcaataaat gtaccgagcg ccatcgacag ccccagcgca tccataaaca
     8881 atgcggaacc caacaccagc agcagcgtcg cggcggtgaa cacttcccgc acgccagaag
     8941 ctgcaataaa gcggaatacc ggacgcagta aatagcgccc accaatcagc atgccgacaa
     9001 acgccagcac cttcatgccg accttcatcc agtcgaaatg ttcgtctgcc gaccccgcca
     9061 acaacggcac taacgccagt gctgggatta ctgccagatc ctgaaacagc agaaccgaaa
     9121 acccgagctg gccggattcg ctgcgattca tccctttctc acgcatcaat tgcaacgcca
     9181 ttgcagttga agacatcgca aggccaatgc caccgaccac cgccgcctgc caggcgaaat
     9241 ccgtcagcat caataatccc gccagcaacg ccgcgcttaa cagcacctgt gccgcgccta
     9301 cgccaaaaat cgaacgccgc agttgccaaa gtttggaggg attcaactca aggccgatga
     9361 taaacatcag gaataccacg ccgagttccg aaaagtggag gatctcatcg acgtcgctaa
     9421 taaaccccag cccccacggg ccaattgcaa tccctgccag caaatatccc aacacagcgc
     9481 caatacccag ccgcgatgcc agcggcaccg cagccaccgc cgcgaagaga aacagcactc
     9541 ctgcgagtaa aaaatcggaa ccttccatca gcggcctcct ggagacagcg gatttgccag
     9601 ccagtcaccg taggctctgg cgtggctcgc cagctcctgt gcgctttgcc gtctcgccca
     9661 gtaaataatg atgggactta accaatgcat ccggcacatg cccgccgcca gttcaaaggg
     9721 gcgcagcaca tcgctcatcg ggtagcgatt cagcgcgtca taacggtaag cactttccgg
     9781 ctcgccggtg gtaatcacgc tacgccagta ctttcccgcc agttggtttc ctcccggccc
     9841 gctggcaaaa ccacgactta atacccggtc cagccactct ttcagtagcg ccgggcagct
     9901 ataggtataa agaggatgct gaaagacaat cacctcgtgc tcgcgcagta atgcctgctc
     9961 acgggggata tcaataaaaa aatcgggata gtgcgcgtaa aggtcgtgca cggtaacatt
    10021 gctgagctgc gtggccggtt taagcagtac ccggtttgcc accgagtcct gagattccgg
    10081 atgggcatac agcagcaaaa ctttcgctgg ctgagacatc atccccctcc cggtatggtt
    10141 tttgtgtata gtcgctgttt tgggctacca ttgcgcccgg tgcggcagct cgcccataca
    10201 ttacattatc ataatgataa gttaacatag tctgaacata cggcacctta tgattgtttt
    10261 ctcctcgtta caaattcgtc gcggcgtgcg cgtcctgctg gataatgcca ccgccaccat
    10321 caaccctggg cagaaagtcg gcctggtggg taaaaacggc tgtggtaaat ctaccctgct
    10381 ggcattgctg aaaaatgaaa tcagcgccga cggcggcagc tacacctttc cgggaagctg
    10441 gcaactggcg tgggtgaatc aggaaacgcc ggcgttaccg caagcggcgc tggaatatgt
    10501 cattgacggc gaccgtgaat atcgtcaact agaagcgcag ctacacgacg ccaacgaacg
    10561 taacgacggg cacgccattg cgaccattca tggcaagctg gatgctattg acgcatggag
    10621 tattcgctcc cgtgctgcca gcctgctgca cggcctcggt ttcagcaatg aacaactgga
    10681 gcgcccggta agtgattttt ccgggggctg gcgtatgcgt cttaaccttg cccaggcgct
    10741 gatttgccgt tcagacttgc tgctgctcga cgaaccgact aaccacctcg atctcgatgc
    10801 cgttatctgg ctggaaaaat ggctgaagag ctatcagggc acgctgatcc tgatctctca
    10861 cgaccgcgac ttcctcgatc cgatcgtcga taaaattatt catatcgaac aacaaagcat
    10921 gttcgagtac accggcaact acagttcgtt tgaagtacag cgcgccaccc gtctggcgca
    10981 gcaacaagcg atgtacgaaa gccagcagga acgcgtagcg catctgcaaa gttatatcga
    11041 ccgtttccgt gccaaagcca ccaaagcgaa gcaggcccag agccgcatta agatgctcga
    11101 gcgtatggag ctaattgccc ccgcgcacgt cgacaacccg ttccgcttta gcttccgcgc
    11161 gccggaaagc ctgccaaatc cgttactgaa gatggaaaaa gtcagcgcgg gctatggcga
    11221 tcgcattatt ctcgactcga ttaaactgaa cctggtgccc ggctcgcgta ttggtctgtt
    11281 aggccgcaat ggcgcgggta aatcgacatt aatcaaactg ttagccggtg aacttgcgcc
    11341 agtcagcggt gaaattggtc tggcgaaagg gatcaaactc ggctacttcg cccagcatca
    11401 acttgaatac ctgcgcgccg acgaatcacc tattcaacat ctggcacgtt tagcgccgca
    11461 ggagctggaa caaaaactgc gtgactacct cggcggcttt ggtttccagg gcgataaagt
    11521 aaccgaagaa acgcgccgct tctccggtgg ggaaaaagcc cgcctggtgc tggcattaat
    11581 tgtctggcag cggccgaatc tgctgctgct cgacgaaccg actaaccacc ttgacctcga
    11641 catgcgtcag gcactcaccg aagcattaat cgagtttgaa ggcgcgctgg ttgtcgtttc
    11701 gcacgaccgt catttgctgc gttccaccac tgacgatctc tacctggttc acgatcgtaa
    11761 agtcgaaccg ttcgacggcg atctggaaga ttatcaacag tggttgagcg acgtacaaaa
    11821 gcaggaaaac cagaccgacg aagcgccaaa agagaatgcg aacagcgccc aggcacgtaa
    11881 agatcagaag cgtcgggaag ctgagctgcg tgcgcaaacc cagccactgc gtaaagagat
    11941 tgcccgtctg gaaaaagaga tggagaagct gaacgcgcaa ctggcgcagg cggaagagaa
    12001 actcggcgac agcgaactgt atgaccagag ccgtaaagcg gagttgaccg cctgcctgca
    12061 acagcaagcc agcgccaaat ccggcctgga agagtgcgaa atggcatggc tggaagccca
    12121 ggagcagctt gagcagatgc tgctggaagg ccaaagcaac tgatggcgca gataacgacg
    12181 accgatgcca atgaattcag cagcagtgct gaattcatcc ccatgcgcgg ctttagcaat
    12241 tgtcatctgc aaaccatgct gccgcgtctg tttcgtcgtc aggtgaaatt caccccgtac
    12301 tggcagcggc tggagttgcc cgacggcgat tttgtcgatc ttgcgtggag tgaaaaccct
    12361 gcacaggcgc aacataaacc tcgtctggtg gtgtttcacg ggctggaagg cagtctcaac
    12421 agcccttacg cccacggtct ggttgaggcg gcgcaaaagc gcggctggct gggcgtggtg
    12481 atgcattttc gcggatgcag cggtgaacca aaccgtatgc accgcattta ccattcgggc
    12541 gaaaccgaag acgccagttg gtttttacgc tggctgcaac gcgaatttgg tcatgcgcca
    12601 acggctgccg tcggctattc gctcggcggt aatatgctgg cctgtttgct ggcaaaggaa
    12661 ggcaatgatc tcccggttga tgcggcggtg attgtctctg cgccgtttat gctggaagcc
    12721 tgtagctatc atatggaaaa gggcttttcc cgcgtttatc agcgttactt gctgaacctg
    12781 ttaaaagcca atgccgcgcg caagctggca gcctaccccg gaacgctgcc gattaatctc
    12841 gcgcagttaa aatcggtacg tcgcatccgt gaatttgacg atctcatcac cgccagaatt
    12901 cacggctacg ccgacgctat cgactattat cgtcagtgta gcgccatgcc gatgctgaac
    12961 cggatcgcca aaccgacgct gattattcac gccaaagacg atccgtttat ggatcatcag
    13021 gtgatcccga aaccggaaag tctccccccg caggtggagt atcaactgac tgaacatggc
    13081 ggtcatgttg gctttattgg cggtacatta cttcatccac aaatgtggct ggagtcacgc
    13141 attcctgact ggttaacaac gtatctggag gcgaaatcat gttgattccg tggcaagacc
    13201 tctcccccga aacgctggaa aatttaattg aaagctttgt gttacgtgaa ggcaccgatt
    13261 atggtgaaca tgagcgtaca cttgaacaga aagtcgccga cgtcaaacgc cagctacagt
    13321 gcggagaagc ggtgctggta tggtcggagc tgcacgaaac ggtcaatatt atgccgcgca
    13381 gtcagtttcg cgaataacct gcaaccgtcg gcggacgaga taataatgat agctaagtca
    13441 tggagttact atgtctgcca aacatccggt cattgcggta acaggatcca gcggcgcggg
    13501 gaccaccacc accagcctcg cgtttcgtaa aatattcgcg cagttaaatc tgcatgcagc
    13561 tgaggtggaa ggcgacagtt ttcaccgtta cacccgcccg gaaatggaca tggcgatccg
    13621 caaagcgcgc gacgccgggc ggcatatcag ctacttcggc cccgaggcta acgacttcgg
    13681 cctgctggaa caaaccttca ttgaatacgg tcagagcggc aaagggaaat ctcgcaaata
    13741 tctgcatacc tacgacgaag ccgtaccgtg gaatcaggta ccggggacat tcaccccctg
    13801 gcaaccttta ccggaaccca ctgatgtact gttttatgaa ggtttacacg gcggcgtagt
    13861 cacgccacag cataacgttg cgcagcatgt ggacttactg gtcggcgtgg tgcctatcgt
    13921 taaccttgag tggattcaaa aactgatccg cgacaccagc gagcgcgggc actcacgaga
    13981 agcagtgatg gactcagtag tgcgttcaat ggaagactat atcaactaca tcacaccgca
    14041 gttttcccgc acccatctta acttccagcg cgttcccacc gtcgacactt caaacccgtt
    14101 cgcggcaaaa ggtatcccgt cgctcgatga aagctttgtg gtgatccatt ttcgtaatct
    14161 ggaagggatc gatttcccct ggctgctggc gatgttgcaa ggctcattca tttcccacat
    14221 caatacgtta gtggtaccgg gcggcaaaat gggtctggca atggaattaa ttatgctgcc
    14281 gctggtgcaa cgattgatgg aaggaaagaa aatcgagtaa ctctgctatt acgccggata
    14341 aaatactatc cggcttcaca acgggatagt taagtcacgc ggcaaccact tcatacgagt
    14401 gagtaatatt caccgctttt tccagcatca acgccactga acaatatttc tcggcagaga
    14461 gatcaaccgc acgcgcaacc gctgcgtctt tcaggtcgcg accggtgacg ataaaatgca
    14521 gattaatgtg cgtaaacagg cgtggtgcct cttcgcggcg ttcagaggtc aattttactt
    14581 cacaatcgac cacatcctga cgcccttttt gcaggatcga aaccacatcg atggcactgc
    14641 aaccacccgc cgccatcaac accatttcca tcggacttgg tgctttatcg cctgagttgc
    14701 cgtccattaa aatctgatga ccagaggcgg attcgcccag aaaagttaac ccttcgaccc
    14761 acttcactcg cgcttgcatt tttgctactc cactgcgtca attttcctga cagagtacgc
    14821 gtactaacca aatcgcgcaa cggaaggcga cctgggtcat gctgaagcga gacaccagga
    14881 gacacaaagc gaaagctatg ctaaaacagt caggatgcta cagtaataca ttgatgtact
    14941 gcatgtatgc aaaggacgtc acattaccgt gcagtacagt tgatagcccc ttcccaggta
    15001 gcgggaagca tatttcggca atccagagac agcggcgtta tctggctctg gagaaagctt
    15061 ataacagagg ataaccgcgc atggtgcttg gcaaaacgca aacagacccg actctcgaat
    15121 ggttcttgtc tcattgccac attcataagt acccatccaa gagcacgctt attcaccagg
    15181 gtgaaaaagc ggaaacgctg tactacatcg ttaaaggctc tgtggcagtg ctgatcaaag
    15241 acgaagaggg taaagaaatg atcctctcct atctgaatca gggtgatttt attggcgaac
    15301 tgggcctgtt tgaagagggc caggaacgta gcgcatgggt acgtgcgaaa accgcctgtg
    15361 aagtggctga aatttcgtac aaaaaatttc gccaattgat tcaggtaaac ccggacattc
    15421 tgatgcgttt gtctgcacag atggcgcgtc gtctgcaagt cacttcagag aaagtgggca
    15481 acctggcgtt cctcgacgtg acgggccgca ttgcacagac tctgctgaat ctggcaaaac
    15541 aaccagacgc tatgactcac ccggacggta tgcaaatcaa aattacccgt caggaaattg
    15601 gtcagattgt cggctgttct cgtgaaaccg tgggacgcat tctgaagatg ctggaagatc
    15661 agaacctgat ctccgcacac ggtaaaacca tcgtcgttta cggcactcgt taatcccgtc
    15721 ggagtggcgc gttacctggt agcgcgccat tttgtttccc ccgatgtggc gcagactgat
    15781 ttatcacccc gatatcaact atgcacttcg acaaacgctg gtgctatgtt tgcccgtggc
    15841 cgttgggtta atgcttggcg aattacgatt cggtctgctc ttctccctcg ttcctgcctg
    15901 ttgcaatatt gcgggccttg atacgcctca taaacgtttt ttcaaacgct taatcattgg
    15961 tgcgtcgctg tttgccacct gtagcttgct gacacagcta ctactggcaa aagatgttcc
    16021 cctgcccttt ttgctgaccg gattaacgct ggtacttggc gtcactgctg agctggggcc
    16081 attgcacgca aaattgcttc ctgcatcgct gctcgccgcc atttttaccc tcagtttggc
    16141 gggatacatg ccggtctggg aaccgttgct catctatgcg ttgggcactc tctggtacgg
    16201 attgtttaac tggttttggt tctggatctg gcgcgaacaa ccgctgcgcg agtcactaag
    16261 tctgctgtac cgtgaactgg cagattattg tgaagccaaa tacagcctgc ttacccagca
    16321 caccgaccct gaaaaagcgc tgccgccgct gctggtgcgc cagcaaaaag cggtcgatct
    16381 aattacccag tgctatcagc aaatgcatat gctttccgcg caaaataata ctgactacaa
    16441 gcggatgctg cgtattttcc aggaggcgct ggatttacag gaacatattt cggtcagttt
    16501 gcatcagccg gaagaggtgc aaaagctggt cgagcgtagc catgcggaag aagttatccg
    16561 ctggaatgcg caaaccgtcg ccgctcgcct gcgcgtgctg gctgatgaca ttctttacca
    16621 tcgcctgcca acgcgtttta cgatggaaaa gcaaattggc gcactggaaa aaatcgcccg
    16681 ccagcatccg gataatccgg ttgggcaatt ctgctactgg catttcagcc gcatcgcccg
    16741 cgtgctgcgc acccaaaaac cgctctatgc ccgtgactta ctggccgata aacagcggcg
    16801 aatgccatta cttccggcgc tgaaaagtta tctgtcacta aagtctccgg cgctacgcaa
    16861 tgccggacga ctcagtgtga tgttaagcgt tgccagcctg atgggcaccg cgctgcatct
    16921 gccgaagtcg tactggatcc tgatgacggt attgctggtg acacaaaatg gctatggcgc
    16981 aacccgtctg aggattgtga atcgctccgt gggaaccgtg gtcgggttaa tcattgcggg
    17041 cgtggcgctg cactttaaaa ttcccgaagg ttacaccctg acgttgatgc tgattaccac
    17101 cctcgccagc tacctgatat tgcgcaaaaa ctacggctgg gcgacggtcg gttttactat
    17161 taccgcagtg tataccctgc aactattgtg gttgaacggc gagcaataca tccttccgcg
    17221 tcttatcgat accattattg gttgtttaat tgctttcggc ggtactgtct ggctgtggcc
    17281 gcagtggcag agcgggttat tgcgtaaaaa cgcccatgat gctttagaag cctatcagga
    17341 agcgattcgc ttgattctta gcgaggatcc gcaacctacg ccactggcct ggcagcgaat
    17401 gcgggtaaat caggcacata acactctgta taactcattg aatcaggcga tgcaggaacc
    17461 ggcgtttaac agccattatc tggcagatat gaaactgtgg gtaacgcaca gccagtttat
    17521 tgttgagcat attaatgcca tgaccacgct ggcgcgggaa caccgggcat tgccacctga
    17581 actggcacaa gagtatttac agtcttgtga aatcgccatt cagcgttgtc agcagcgact
    17641 ggagtatgac gaaccgggta gttctggcga tgccaatatc atggatgcgc cggagatgca
    17701 gccgcacgaa ggcgcggcag gtacgctgga gcagcattta cagcgggtta ttggtcatct
    17761 gaacaccatg cacaccattt cgtcgatggc atggcgtcag cgaccgcatc acgggatttg
    17821 gctgagtcgc aagttgcggg attcgaaggc gtaatgcagg ctaaaccatc ggataaggca
    17881 ttcacgccgc atccgacatc ttttgcctga tgcttcgtat ttacgcccca accaccttcg
    17941 ccaccgcgtg ggcgaaacgt tgcatccctt catcgatatc cgcatcttcc accaccagcg
    18001 acggtgcaaa acgcatcaca tccggtccgg cattcagcac cattacgcca gcctctgcgc
    18061 ccgcatacag gaaatcacgc gcccgacctt tgtactgtgg tttcagctct gcgccaatca
    18121 acagccccat accgcgaata tcgctaaata catcgtactg ctgatcgatc ttctgcagat
    18181 ggtcaacaaa acgctggcgt ttcgcctgaa tgccttccag cacttcaggg gtattgatga
    18241 tatcaaacgc cgcccccgct actgcacagg ccagaggatt accgccgtag gtggaaccgt
    18301 gagaaccagg atgaaacgca gaagcaattt ccgccgtggt cagcatggcg ctaatcggga
    18361 agccgccgcc taacgctttc gcagaggtca gaatatccgg cgtaacgccg tagtgcatgt
    18421 aagcaaacaa atcgccggtc cgccccatcc cgcactgcac ttcatcaaac accaataatg
    18481 cctgatgttg atcgcacagc tcgcgcaagc cctgcaaaaa ctctggcgtc gctgccgtca
    18541 caccgccctc gccctggatc ggctcaacca ccaccgcaca ggtgtgatca tccatcaccg
    18601 ctttcactgc atggagatcg ttaaagggaa cgtggatgat gtctgccggt ttcggcccaa
    18661 agccgtcgga atattttggc tgcccaccca ccgaaacggt aaacagcgag cgaccatgaa
    18721 aagcgttatg gaaggcaata attttggttt tgaacgggct atgacgcaca caggcgtaat
    18781 ggcgtgccag tttaaaggcg gtttcgttag cttccgtgcc ggagttcata aacaccacgc
    18841 gttcggcaaa cgttgcctca atcagtttac gcccaagacg cagcgccggt tcattggtga
    18901 aaacgttact gatatgccac agagtttcgc cctgggtttt taacgcgttc accagcgcag
    18961 gatggcaatg gcccaacgcc gtaactgcaa tgccacccgc gaaatcgaca tactccttgc
    19021 cttgctgatc ccagattcgg ctgccctgac cttttaccgg aataaactct gccggagcat
    19081 aaatcggcag gatcacttca tcgaaagtcg cgcgtgtaat tgctgtttgt tcaattgcca
    19141 tctcatgatc accctgttac gcataaacaa atgtgaaatt ataaccacaa aatatgcata
    19201 aaaaatcact aaatggcaat cagaaatcag cgatgcagga aattagccag cagttgatgt
    19261 ccttgttcgc taagaatact ttctggatgg aactgcacac cttccagatc ccactggcga
    19321 tggcgaatcc ccataatctc gcgggtttcg ctccaggccg tcacgtcaaa gcacgctggt
    19381 aatgagtcag gttccaccac cagcgaatgg tagcgtgtca cggtaagtgg atttgccagc
    19441 ccccgaaata cgccctcacc gttatgtgta atcggcgagg ttttgccgtg catgaccttt
    19501 gcggcgcgca caactttacc gccaaatgcc tgcgccattg cctgatgacc gaggcagacg
    19561 ccaagaatcg gcaagcgccc ggcatagtgg cgaataacgt caagggagat cccggcttca
    19621 tctggcgtac aggggccagg tgagatgaca attttttgtg gtttaagggc gtcgatatcc
    19681 gccagcgtca acgcatcgtt gcgcttaacc agcacatccg cccccagttc acaaaagtac
    19741 tggtagaggt tccaggtaaa agaatcgtag ttatctataa gcaggatcat ggcggctccg
    19801 gtacaaaaga accgcgctat tttactcaga ttccccggct tcgcttacca ctttgctaaa
    19861 tatcatctgc agtgcggtga gatcccccat tgccccactc tgatttgcct gattccaggc
    19921 ctctttttcg ataccctgcc agctcagttg atatccggca tgaatcgcca gttgctcgaa
    19981 gaagatccgc tgtgccagac cacttcccac ccggaaggga tgcagcacgt tgatttcaca
    20041 atagtaatgc gccagccgct cgacgaactt cgctttctcc aggccaacca gataaccttc
    20101 ttcctccaga tcctgcatca gggcattgcc ctctttttcg atataagcaa agtggcagaa
    20161 cggcgtatca ccctgataaa tatcaacttc acgcagttgc cctgcccagt cgaaaatatc
    20221 ctgatacagc tggcgatgga tagttcgcaa atgcggtaaa ccgcgcacca gcggaccaag
    20281 ctcaatggtc gcagcacgca gcgccgtcat ttcgtaagcg gcctgttcca gccgctgctg
    20341 ctggcggatg ttcagccggt tacgcatgat atcaaggcct ggataaagat acggatcgcg
    20401 cccttcgccg aatttatcgc tcatagtgac tcctcagctc ttcaaggcgc gctaaagcct
    20461 ctgcggcagt aagagtgact aaaggcatct cgacgccttc aagacggcga ctggcctgaa
    20521 aattacgatt acgctgaagc tcccagagac gggacttttg cttatcggtg agtttcttca
    20581 cttgatgcct ccctgaacgt gtccatttgc cacaagtata agcggcaaat ccgggttacg
    20641 ccgggagagc agaagcgcgg gcaagattgc ccgcgcgaga aatcattacg gcaggacttt
    20701 agcggaaagg ataactaccg gttttgacgg cacattctgg tacggaccaa cgtcatgagt
    20761 cggcacctgg gaaatcttat cggcaacgtc catgcctttc accactttac caaataccgc
    20821 gtaaccgaaa tcacgctgac catggtcaag gaaggcgtta tcggcaacgt tgataaagaa
    20881 ctggctggtg gcgctgtctt tgtcagcggt acgtgccatc gcgatggtgc cacgcgtgtt
    20941 gcgcaggccg ttatcggctt catttttgat tggcgggttt ggttttttct gctgcatctg
    21001 ctcggtgaaa ccgccgccct gaatcataaa gccaggaatg acgcggtgaa aggtagtgtt
    21061 gttataaaaa ccgctgttca cataatcgac aaagttttgc acagacactg gcgctttttg
    21121 tttatccagc tccagttcga tgttaccagc tgaggttgtc aacaatacgt gcgggtcccc
    21181 tttcgctgcc attgctgcgg gagaaagagc agaaagagcg aaaacagcag ccatcgccgc
    21241 cagggtcgat ttgaacatga gatttcctta acaaacagag cagaaaaaaa gcaagtgaag
    21301 agattctaaa tagccttcaa gaacaaggcc atccctttac ctaattttac gtatctgaaa
    21361 tatatgtaac ctgacgatca ctttttattc cgtgatcaaa atcacctctt aaaatgcaat
    21421 ttagcaaccg attgcaataa aacatttaaa cagatcacaa aatcacctaa aatcgcccgc
    21481 tcgcggcata tcccgctatg ccattttatt tttgaacgca ggccaatcat gactaacagc
    21541 aatcgcatca agctcacatg gattagcttt ctctcctacg cactgactgg tgcgttggtt
    21601 attgtcaccg ggatggtgat gggaaatatc gccgattatt tcaatctgcc tgtttccagt
    21661 atgagtaata ccttcacctt cctcaacgcc ggcattttaa tctctatctt cctcaacgcc
    21721 tggctgatgg aaatcgtccc gttgaaaacg cagttacgtt ttggctttct cctgatggtg
    21781 ctggcggttg ccggtttgat gttcagccac agcctggcgc tgttctcggc ggcgatgttc
    21841 attctcgggg tggtcagcgg catcaccatg tcgattggta cattcctggt aacacaaatg
    21901 tatgaagggc gtcagcgcgg ttcccgcctg ttatttaccg actccttctt cagtatggct
    21961 gggatgattt tcccaatgat cgccgcgttt ctactggcgc gcagcattga gtggtactgg
    22021 gtttatgcct gcatcgggct ggtgtatgtc gctattttta ttctgacctt cggctgtgag
    22081 ttcccggcgc tgggcaaaca tgcgccaaaa acggatgctc cggtagagaa agaaaagtgg
    22141 gggatcggcg tactgtttct ctctgttgcg gcgttgtgct acatcctcgg tcagttaggt
    22201 tttatctcct gggtgcctga gtatgccaaa ggcctgggca tgagcctgaa cgacgcgggc
    22261 acgctggtga gtaacttctg gatgtcatac atggtcggca tgtgggcgtt cagctttatt
    22321 cttcgcttct ttgatttgca acgcattctg accgtactgg ctggtctggc tgcgattctg
    22381 atgtacgtct ttaacaccgg aacaccagca catatggcgt ggtcaattct cgctctgggc
    22441 ttcttctcca gcgcgatcta taccaccatc atcaccctgg gttcacagca gaccaaagta
    22501 ccgtcgccaa aactggttaa ctttgtcctg acctgcggaa ccatcggtac tatgttgacc
    22561 tttgtggtta ccggcccgat cgttgaacat agcggtccgc aggcggcact gcttacagca
    22621 aacggtctgt acgctgtcgt ctttgtgatg tgcttcctgt taggtttcgt cagccgtcac
    22681 cgtcagcata acaccctgac ctctcattaa ttgctcatgc cggacggcac tatcgtcgtc
    22741 cggccttttc ctctcttccc ccgctacgtg catctatttc tataaacccg ctcattttgt
    22801 ctattttttg cacaaacatg aaatatcaga caattccgtg acttaagaaa atttatacaa
    22861 atcagcaaca tacccattaa ggagtatata aaggtgaatt tgatttacat caataagcgg
    22921 ggttgctgaa tcgttaaggt aggcggtaat agaaaagaaa tcgaggcaaa aatgagcaaa
    22981 gtcagactcg caattatcgg taacggtatg gtcggccatc gctttatcga agatcttctt
    23041 gataaatctg atgcggccaa ctttgatatt accgttttct gtgaagaacc gcgcatcgct
    23101 tatgaccgcg tacacctctc gtcttacttc tctcaccaca ccgccgaaga gctgtcgctg
    23161 gtgcgcgaag gcttctacga gaaacacggc atcaaagttc tggtcggcga acgcgctatc
    23221 accatcaacc gtcaggagaa ggtgattcac tccagcgccg gacgtaccgt tttttatgac
    23281 aagctgatca tggcaaccgg ttcctacccg tggatcccgc caatcaaagg ttctgatact
    23341 caggactgct ttgtctatcg cactattgaa gacctcaacg ccattgaatc ctgcgcccgt
    23401 cgcagcaaac gcggtgccgt tgttggtggc ggcctgttag gtctggaagc cgcaggcgcg
    23461 ctgaaaaact taggtattga aacccacgtt atcgaatttg cccctatgct gatggcagaa
    23521 cagcttgatc agatgggcgg cgagcagctg cgtcgcaaaa tcgaaagtat gggcgtgcgc
    23581 gttcacacca gcaaaaacac ccttgagatt gtgcaggaag gtgttgaagc gcgtaaaacc
    23641 atgcgttttg ccgacggcag cgaactggaa gtcgacttta tcgtcttctc taccggtatc
    23701 cgtccgcgcg ataagctggc aacccagtgt ggtctggacg ttgctccgcg tgggggtatt
    23761 gtcattaatg attcctgcca gacttccgat ccggatatct acgccatcgg tgaatgcgca
    23821 agctggaaca accgtgtatt tggtctggta gcacctggct acaaaatggc gcaggtcgcc
    23881 gttgaccata ttctcggtag cgaaaacgcc tttgaaggtg ctgaccttag cgccaagctg
    23941 aaactgctgg gcgtagacgt aggcggtatt ggtgatgcgc acggtcgcac gcctggcgca
    24001 cgtagctacg tttacctcga cgaaagtaaa gagatctaca aacgcctgat tgtcagcgaa
    24061 gacaacaaaa ccctgctcgg tgcggtactg gtgggcgata ccagcgacta cggtaacctg
    24121 ctgcaactgg tgctgaacgc tatcgaactg ccggaaaacc cggattccct gatcctgcca
    24181 gcacactcgg gtagcggcaa gccgtctatc ggtgttgata aactgccgga cagcgcgcaa
    24241 atctgctcct gcttcgacgt caccaaaggt gatctgattg ctgccatcaa caaaggctgc
    24301 cacacagttg cggcgctgaa agctgaaacc aaagcgggta ctggctgcgg tggctgtatc
    24361 ccgctggtca ctcaggtact gaacgcggaa ctggcgaaac agggcatcga agttaacaac
    24421 aacctgtgcg aacactttgc ttattcgcgt caggaactgt tccatttgat ccgcgttgaa
    24481 ggcattaaaa ccttcgaaga actgctggcg aaacacggca aaggctacgg ttgtgaagtt
    24541 tgtaaaccaa ccgtcggttc gctgctggcc tcctgctgga acgaatacat tctgaagccg
    24601 gaacatactc cgctgcagga ttctaacgac aacttcctcg ctaacatcca gaaagacggc
    24661 acctactcgg tgatcccgcg ttctccgggc ggtgaaatca ccccggaagg gctgatggcg
    24721 gtaggtcgta tcgcgcgtga atttaatctc tacaccaaga tcactggctc ccagcgtctg
    24781 gcgatgtttg gcgcacagaa agacgatctg ccggagatct ggcgtcagct gattgaagcc
    24841 ggcttcgaaa ccggtcatgc ctatgcgaaa gcactgcgta tggcgaaaac ctgcgtgggt
    24901 agcacctggt gccgctacgg cgttggcgac agcgtcggcc tcggcgtgga actggaaaac
    24961 cgctacaaag gcatccgtac gccgcacaaa atgaagttcg gtgtctccgg ctgtacccgt
    25021 gaatgttcag aagctcaggg taaagacgtg ggtattatcg ccactgaaaa aggctggaac
    25081 ctgtatgttt gcggtaacgg cggcatgaaa ccgcgtcatg cggatctgct ggcggcggat
    25141 atcgatcgcg aaacgctgat caaatatctc gaccgcttca tgatgttcta catccgtact
    25201 gccgacaaac tgacgcgtac cgcaccgtgg ttagaaaacc tcgaaggcgg catcgattac
    25261 ctgaaagcag tgatcattga cgacaaactg gggctgaacg cacatctgga agaagagatg
    25321 gcgcgcctgc gtgaagcggt actgtgtgag tggactgaaa cggtcaatac gccgtctgcg
    25381 cagactcgct tcaaacactt catcaacagc gacaagcgtg acccgaacgt gcagatggtg
    25441 ccagagcgcg aacagcaccg tccggcaacg ccgtatgaac gtatcccagt aactctggtg
    25501 gaggacaacg catgagccag tggaaagaca tctgcaaaat cgatgacatc ctgcctgaaa
    25561 ccggcgtctg cgcgctgtta ggtgacgagc aggtcgcgat tttccgcccg tatcacagcg
    25621 atcaggtgtt tgcgatcagc aacatcgacc cgttcttcga gtccagcgtg ctgtcacgcg
    25681 gactgattgc ggaacaccag ggcgagctgt gggtcgccag cccgctgaaa aaacagcgtt
    25741 ttcgcttaag cgacggcttg tgcatggaag acgaacagtt ttccgtcaaa cattacgaag
    25801 cgcgagtgaa agacggcgtg gtgcagctgc gcggttaatg ttttaacggg aggcgcaatg
    25861 cctccccttt ttgcatggtc ctgtaataat cttcggtat
//
LOCUS       DAPOAV010000065        25276 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.065, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000065 DAPOAV010000000
VERSION     DAPOAV010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25276
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.065"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            19..438
                     /locus_tag="RN951_003015"
     CDS             19..438
                     /locus_tag="RN951_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
                     /protein_id="HDX2527986.1"
                     /translation="MLFIKPADLREIVTFPLFSDLVQCGFPSPAADYVEQRIDLNQLL
                     IQHPSATYFVKASGDSMIDGGISDGDLLIVDSAITASHGDIVIAAVDGEFTVKKLQLR
                     PTVQLIPMNSAYSPITISSEDTLDVFGVVIHVVKAMR"
     gene            438..1706
                     /gene="umuC"
                     /locus_tag="RN951_003016"
     CDS             438..1706
                     /gene="umuC"
                     /locus_tag="RN951_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase V catalytic protein"
                     /protein_id="HDX2527987.1"
                     /translation="MFALCDVNAFYASCETVFRPDLWGKPVVVLSNNDGCVIARNAEA
                     KALGVKMGDPWFKQKDLFRRCGVVCFSSNYELYADMSNRVMSTLEELSPRVEIYSIDE
                     AFCDLTGVRNCRDLTDFGREIRATVLQRTHLTVGVGIAQTKTLAKLANHAAKKWQRQT
                     GGVVDLSNLERQRKLMSALPVDDVWGIGRRISKKLDAMGIKTVLDLADTDIRFIRKHF
                     NVVLERTVRELRGEPCLQLEEFAPTKQEIICSRSFGERITDYPSMRQAICSYAARAAE
                     KLRSEHQYCRFISTFIKTSPFALNEPYYGNSASVKLLTPTQDSRDIINAATRSLDAIW
                     QAGHRYQKAGVMLGDFFSQGVAQLNLFDDNAPRPGSEQLMTVMDTLNAKEGRGTLYFA
                     GQGIQQQWQMKRAMLSPRYTTRSSDLLRVK"
     gene            complement(1752..2282)
                     /gene="dsbB"
                     /locus_tag="RN951_003017"
     CDS             complement(1752..2282)
                     /gene="dsbB"
                     /locus_tag="RN951_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="disulfide bond formation protein DsbB"
                     /protein_id="HDX2527988.1"
                     /translation="MLRFLNQCSQGRGAWLLMAFTALALELTALWFQHVMLLKPCVLC
                     IYERCALFGVLGAALIGAIAPKTPLRYVAMVIWLYSAFRGVQLTYEHTMLQLYPSPFA
                     TCDFMVRFPEWLPLDKWVPQVFVASGDCAERQWDFLGLEMPQWLLGIFIAYLIVAVLV
                     VISQPFKAKKRDLFGR"
     gene            complement(2428..3969)
                     /gene="nhaB"
                     /locus_tag="RN951_003018"
     CDS             complement(2428..3969)
                     /gene="nhaB"
                     /locus_tag="RN951_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+)/H(+) antiporter NhaB"
                     /protein_id="HDX2527989.1"
                     /translation="MEISWGRALWRNFLGQSPDWYKLALIIFLIVNPLIFLISPFVAG
                     WLLVAEFIFTLAMALKCYPLLPGGLLAIEAVFIGMTSAEHVREEVAANLEVLLLLMFM
                     VAGIYFMKQLLLFIFTRLLLSIRSKMLLSLSFCVAAAFLSAFLDALTVVAVVISVAVG
                     FYGIYHRVASSRTEDTDLQDDSHIDKHYKVVLEQFRGFLRSLMMHAGVGTALGGVMTM
                     VGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLICGLLTCLLVEKLRWFGYGETLPEKV
                     REVLQQFDDQSRHQRTRQDKIRLIVQAIIGVWLVTALALHLAEVGLIGLSVIILATSL
                     TGVTDEHAIGKAFTESLPFTALLTVFFSVVAVIIDQQLFSPIIQFVLQASEHAQLSLF
                     YIFNGLLSSISDNVFVGTIYINEAKAAMESGAITLKQYELLAVAINTGTNLPSVATPN
                     GQAAFLFLLTSALAPLIRLSYGRMVWMALPYTLVLTLVGLLCVEFTLAPVTEWFMQMG
                     WIATL"
     gene            4190..4909
                     /gene="fadR"
                     /locus_tag="RN951_003019"
     CDS             4190..4909
                     /gene="fadR"
                     /locus_tag="RN951_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid metabolism transcriptional regulator
                     FadR"
                     /protein_id="HDX2527990.1"
                     /translation="MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVT
                     RTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLL
                     SVRTNISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAFASGNPI
                     YGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGAHDQVYETVRRYGHE
                     SGEIWHRMQKNLPGDLAIQGR"
     gene            complement(4961..6493)
                     /locus_tag="RN951_003020"
     CDS             complement(4961..6493)
                     /locus_tag="RN951_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoVR family protein"
                     /protein_id="HDX2527991.1"
                     /translation="MATIDSMNKDTTRLSDGPDWTFDLLDVYLAEIDRVAKLYRLDTY
                     PHQIEVITSEQMMDAYSSVGMPINYPHWSFGKKFIETERLYKHGQQGLAYEIVINSNP
                     CIAYLMEENTITMQALVMAHACYGHNSFFKNNYLFRSWTDASSIVDYLIFARKYITEC
                     EERYGVDEVERLLDSCHALMNYGVDRYKRPQKISLQEEKARQKSREEYLQSQVNMLWR
                     TLPKREEEKTVAEARRYPSEPQENLLYFMEKNAPLLESWQREILRIVRKVSQYFYPQK
                     QTQVMNEGWATFWHYTILNHLYDEGKVTERFMLEFLHSHTNVVFQPPYNSPWYSGINP
                     YALGFAMFQDIKRICQSPTEEDKYWFPDIAGSDWLETLHFAMRDFKDESFISQFLSPK
                     VMRDFRFFTVLDDDRHNYLEISAIHNEEGYREIRNRLSSQYNLSNLEPNIQIWNVDLR
                     GDRSLTLRYIPHNRAPLDRGRKEVLKHVHRLWGFDVMLEQQNEDGSIELLERCPPRMG
                     NL"
     gene            6823..8121
                     /gene="dadA"
                     /locus_tag="RN951_003021"
     CDS             6823..8121
                     /gene="dadA"
                     /locus_tag="RN951_003021"
                     /EC_number="1.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-amino acid dehydrogenase"
                     /protein_id="HDX2527992.1"
                     /translation="MRVVILGSGVVGVASAWYLNQAGHEVTVIDREPGAALETSAANA
                     GQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTQFQLKWMWQMLRNCDTSHYM
                     ENKGRMVRLAEYSRDCLKALRAETNIQYEGRQGGTLQLFRTEQQYENATRDIAVLEDA
                     GVPYQLLESSRLAEVEPALAEVAHKLTGGLQLPNDETGDCQLFTQNLARMAEQAGVKF
                     RFNTPVDQLLCDGEQIYGVKCGDEVIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYS
                     LTIPIAQEDGAPVSTILDETYKIAITRFDNRIRVGGMAEIVGFNTELLQPRRETLEMV
                     VRDLYPRGGHVEQATFWTGLRPMTPDGTPVVGRTRFKNLWLNTGHGTLGWTMACGSGQ
                     LLSDLLSGRTPAIPYEDLSVARYSRGFTPSRPGHLHGAHS"
     gene            8131..9201
                     /gene="dadX"
                     /locus_tag="RN951_003022"
     CDS             8131..9201
                     /gene="dadX"
                     /locus_tag="RN951_003022"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolic alanine racemase DadX"
                     /protein_id="HDX2527993.1"
                     /translation="MTRPIQASLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIE
                     RIWSAIGATDGFALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHS
                     NWQLKALQNARLKAPLDIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHF
                     AEAEHPDGISGAMARIEQAAEGLECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPS
                     GQWRDIANTGLRPVMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGY
                     PRHAPTGTPVLVDGVRTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAA
                     AAGTVGYELMCALALRVPVVTV"
     gene            complement(9587..11323)
                     /locus_tag="RN951_003023"
     CDS             complement(9587..11323)
                     /locus_tag="RN951_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415709.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HDX2527994.1"
                     /translation="MDATTIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGML
                     AGVDGVGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGSALSLATLGVLI
                     TSGLTGMMAAWLFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
                     NDPMAVFLTITLIAMIQHHESNISWMFIVDILQQFGLGIVIGLGGGYLLLQMINRIAL
                     PAGLYPLLALSGGILIFSLTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAW
                     LAQIAMFLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFAGLLPFRGFNLRERV
                     FISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKV
                     VVPPVGRPVSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKETRIAALFRDN
                     QLLHPTGSTRLREGDVLCVIGRERDLPALGKLFSQSPPVALDQRFFGDFILEASAKYA
                     DVALIYGLEDGREYRDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKEDNEVLK
                     IGVRVAEEEAES"
     gene            complement(11418..12332)
                     /gene="ldcA"
                     /locus_tag="RN951_003024"
     CDS             complement(11418..12332)
                     /gene="ldcA"
                     /locus_tag="RN951_003024"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muramoyltetrapeptide carboxypeptidase"
                     /protein_id="HDX2527995.1"
                     /translation="MSLFHLIAPSGYCIKQHAALRGIQRLTDAGHQVNNVEVIARRCE
                     RFAGTETERLEDLNSLARLTTPNTIVLAVRGGYGASRLLADIDWQALVARQQHDPLLI
                     CGHSDFTAIQCGLLAHGNVITFSGPMLVANFGADELNAFTEHHFWLALRNETFTIEWQ
                     GEGPTCRAEGTLWGGNLAMLISLIGTPWMPKIENGILVLEDINEHPFRVERMLLQLYH
                     AGILPRQKAIILGSFSGSTPNDYDAGYNLESVYAFLRSRLSIPLITGLDFGHEQRTVT
                     LPLGAHAILNNTREGTQLTISGHPVLKM"
     gene            12432..13043
                     /gene="emtA"
                     /locus_tag="RN951_003025"
     CDS             12432..13043
                     /gene="emtA"
                     /locus_tag="RN951_003025"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415711.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     EmtA"
                     /protein_id="HDX2527996.1"
                     /translation="MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQ
                     KAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWSGEP
                     TTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSD
                     RKKAISKINDLDADEFLEHVARNHPAPQAPRYIYKLEQALDAM"
     gene            complement(13045..13779)
                     /locus_tag="RN951_003026"
     CDS             complement(13045..13779)
                     /locus_tag="RN951_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar brake protein"
                     /protein_id="HDX2527997.1"
                     /translation="MSHYHEQFLKQNPLAVLGVLRDLHKAAIPLRLSWNGGQLISKLL
                     AITPDKLVLDFGSQAEDNIAVLKAQHITITAETQGAKVEFTVEQLQQSEYLQLPAFIT
                     VPPPTLWFVQRRRYFRISAPLHPPYFCQTKLADNSTLRFRLYDLSLGGMGALLETAKP
                     AELQEGMRFAQIEVNMGQWGVFHFDAQLISISERKVIDGKNETITTPRLSFRFLNVSP
                     TVERQLQRIIFSLEREAREKADKVRD"
     gene            13980..14234
                     /locus_tag="RN951_003027"
     CDS             13980..14234
                     /locus_tag="RN951_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDX2527998.1"
                     /translation="MGIIAWIIFDLIAGIIAKLIMPGRDGGGFFLTCILGIVGAVVGG
                     WLATMFGIGGSISGFNLHSFLVAVVGAILVLGIFRLLRRE"
     gene            14412..14852
                     /locus_tag="RN951_003028"
     CDS             14412..14852
                     /locus_tag="RN951_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2527999.1"
                     /translation="MIQKINILDSSQSGVKNGADSEAVLAALTEHLELINPSGRLSQN
                     TRSAMLQLREEEWSEFFFWLLNSLECLDYVIINLTPESKKTLMSEHRNNIQVAIDALY
                     SQRRRKSPGDESETLTRRNDAIFGNHVWQTFAQYFPPGLEKPSV"
     gene            complement(14931..16628)
                     /gene="treA"
                     /locus_tag="RN951_003029"
     CDS             complement(14931..16628)
                     /gene="treA"
                     /locus_tag="RN951_003029"
                     /EC_number="3.2.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase"
                     /protein_id="HDX2528000.1"
                     /translation="MKSPAPSRPQKMALIPACIFLCFAALSVQAEETPVTPQPPDILL
                     GPLFNDVQNAKLFPDQKTFADAVPNSDPLMILADYRMQQNQSGFDLRHFVNVNFTLPK
                     EGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREVYYWD
                     SYFTMLGLAESGHWDKVADMVANFAHEIDTYGHIPNGNRSYYLSRSQPPFFALMVELL
                     AQHEGDAALKQYLPQMQKEYAYWMDGVENLQAGQQEKRVVKLQDGTLLNRYWDDRDTP
                     RPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQQLNTLRTTSIVP
                     VDLNSLMFKMEKILARASKAAGDNAMANQYETLANARQKGIEKYLWNDQQGWYADYDL
                     KSHKVRNQLTAAALFPLYVNAAAKDRANKMATATKTHLLQPGGLNTTSVKSGQQWDAP
                     NGWAPLQWVATEGLQNYGQKEVAMDISWHFLTNVQHTYDREKKLVEKYDVSTTGTGGG
                     GGEYPLQDGFGWTNGVTLKMLDLICPKEQPCDNVPATRPTVKSATTQPSTKEAQPTP"
     gene            complement(16948..18366)
                     /gene="dhaM"
                     /locus_tag="RN951_003030"
     CDS             complement(16948..18366)
                     /gene="dhaM"
                     /locus_tag="RN951_003030"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415716.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaM"
                     /protein_id="HDX2528001.1"
                     /translation="MVNLVIVSHSSRLGEGVGELARQMLMSDSCKIAIAAGIDDPQNP
                     IGTDAVKVMEAIESVADADHVLVMMDMGSALLSAETALELLAPEIAAKVRLCAAPLVE
                     GTLAATVSAASGADIDKVIFDAMHALEAKREQLGLPSSDTEISDTCPAYDEEARSLAV
                     VIKNRNGLHVRPASRLVYTLSTFNADMLLEKNGKCVTPESINQIALLQVRYNDTLRLI
                     AKGPEAEEALIAFRQLAEDNFGETEEVAPPTLRPVPPVSGKAFYYQPVLCTVQAKSTL
                     TVEEEQDRLRQAIDFTLLDLMTLTAKAEASGLDDIAAIFSGHHTLLDDPELLAAASEL
                     LQHEHCTAEYAWQQVLKELSQQYQQLDDEYLQARYIDVDDLLHRTLVHLTQTKEELPQ
                     FNSPTILLAENIYPSTVLQLDPAVVKGICLSAGSPVSHSALIARELGIGWICQQGEKL
                     YAIQPEETLTLDVKTQRFNRQG"
     gene            complement(18377..19009)
                     /gene="dhaL"
                     /locus_tag="RN951_003031"
     CDS             complement(18377..19009)
                     /gene="dhaL"
                     /locus_tag="RN951_003031"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase ADP-binding subunit
                     DhaL"
                     /protein_id="HDX2528002.1"
                     /translation="MSLSRTQIVNWLTRCGDIFSTESEYLTGLDREIGDADHGLNMNR
                     GFSKVVEKLPAIADKDIGFILKNTGMTLLSSVGGASGPLFGTFFIRAAQATQARQSLT
                     LEELYQMFRDGADGVISRGKAEPGDKTMCDVWVPVVESLRQSSEQNLSVPVALEAASS
                     IAESAAQSTITMQARKGRASYLGERSIGHQDPGATSVMFMMQMLALAAKE"
     gene            complement(19020..20090)
                     /gene="dhaK"
                     /locus_tag="RN951_003032"
     CDS             complement(19020..20090)
                     /gene="dhaK"
                     /locus_tag="RN951_003032"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415718.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HDX2528003.1"
                     /translation="MKKLINDVQDVLDEQLAGLAKAHPSLTLHQDPVYVTRADAPVAG
                     KVALLSGGGSGHEPMHCGYIGQGMLSGACPGEIFTSPTPDKIFECAMQVDGGEGVLLI
                     IKNYTGDILNFETATELLHDSGVKVTTVVIDDDVAVKDSLYTAGRRGVANTVLIEKLV
                     GAAAERGDSLDACAELGRKLNNQGHSIGIALGACTVPAAGKPSFTLADNEMEFGVGIH
                     GEPGIDRRPFSSLDQTVDEMFDTLLVNGSYHRTLRFWDYQQGSWQEEQQTKQPLQSGD
                     RVIALVNNLGATPLSELYGVYNRLTTRCQQAGLTIERNLIGAYCTSLDMTGFSITLLK
                     VDDETLALWDAPVHTPALNWGK"
     gene            20318..22237
                     /gene="dhaR"
                     /locus_tag="RN951_003033"
     CDS             20318..22237
                     /gene="dhaR"
                     /locus_tag="RN951_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415719.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase operon
                     transcriptional regulator DhaR"
                     /protein_id="HDX2528004.1"
                     /translation="MSGAFNNDGRGISPLIATSWERCNKLMKRETWNVPHQAQGVTFA
                     SIYRRKKAMLTLGQAALEDAWEYMAPRECALFILDETACILSRNGDPQTLQQLSALGF
                     NDGTYCAEGIIGTCALSLAAISGQAVKTMADQHFKQVLWNWAFCATPLFDSKGRLTGT
                     IALACPVEQTTAADLPLTLAIAREVGNLLLTDSLLAETNRHLNQLNALLESMDDGVIS
                     WDEQGNLQFINAQAARVLRLDATASQGRAITELLTLPAVLQQAIKQAHPLKHVEATFE
                     SQHQFIDAVITLKPIIETQGTSFILLLHPVEQMRQLMTSQLGKVSHTFAHMPQDDPQT
                     RRLIHFGRQAARSSFPVLLCGEEGVGKALLSQAIHNESERAAGPYIAVNCELYGDAAL
                     AEEFIGGDRTDNENGRLSRLELAHGGTLFLEKIEYLAVELQSALLQVIKQGVITRLDA
                     RRLIPIDVKVIATTTADLAMLVEQNRFSRQLYYALHAFEITIPPLRMRRGSIPALVNN
                     KLRSLEKRFSTRLKIDDDALARLVSCAWPGNDFELYSVIENLALSSDNGRIRVSDLPE
                     HLFTEQATDDVSATRLSTSLSFAEVEKEAIINAAQVTGGRIQEMSALLGIGRTTLWRK
                     MKQHGIDAGQFKRRV"
     gene            complement(22337..25204)
                     /locus_tag="RN951_003034"
     CDS             complement(22337..25204)
                     /locus_tag="RN951_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HDX2528005.1"
                     /translation="MGIKQHNGNTKADRLAELKIRSPSIQLIKFGAIGLNAIIFSPLL
                     IAADTGSQYGTNITINDGDRITGDTADPSGNLYGVMTPAGNTPGNINLGNDVTVNVND
                     ASGYAKGIIIQGKNSSLTANRLTVDVVGQTSAIGINLIGDYTHADLGTGSTIKSNDDG
                     IIIGHSSTLTATQFTIENSNGIGLTINDYGTSVDLGSGSKITTDGSTGVYIGGLNGNN
                     ANGAARFTATDLTIDVQGYSAMGINVQKNSVVDLGTNSTIKTNGDNAHGLWSFGQVSA
                     NALTVDVTGAAANGVEVRGGTTTIGADSHISSAQGGGLVTSGSDAIINFTGTAAQRNS
                     IFSGGSYGASAQTATAVVNMQNTDITVDRNGSLALGLWALSGGRITGDSLAITGAAGA
                     RGIYAMTNSQIDLTSDLVIDMSTPDQMAIATQHDDGYAASRINASGRMLINGSVLSKG
                     GLINLDMHPGSVWTGSSLSDNVNGGKLDVAMNNSVWNVTSNSNLDTLALSHSTVDFAS
                     HGSTAGTFATLNVENLSGNSTFIMRADVVGEGNGVNNKGDLLNISGSSAGNHVLAIRN
                     QGSEATTGNEVLTVVKTTDGAASFSASSQVELGGYLYDVRKNGTNWELYASGTVPEPT
                     PNPEPTPAPAQPPIVNPDPTPEPAPTPKPTTTADAGGNYLNVGYLLNYVENRTLMQRM
                     GDLRNQSKDGNIWLRSYGGSLDSFASGKLSGFDMGYSGIQFGGDKRLSDVMPLYVGLY
                     IGSTHASPDYSGGDGTARSDYMGMYASYMAQNGFYSDLVIKASRQKNSFHVLDSQNNG
                     VNANGTANGMSISLEAGQRFNLSPTGYGFYIEPQTQLTYSHQNEMTMKASNGLNIHLN
                     HYESLLGRASMILGYDITAGNSQLNVYVKTGAIREFSGDTEYLLNNSREKYSFKGNGW
                     NNGVGVSAQYNKQHTFYLEADYTQGNLFDQKQVNGGYRFSF"
BASE COUNT         6223 a         6310 c         6544 g         6199 t
ORIGIN      
        1 aacttcaggc agattattat gttgtttatc aagcctgcgg atctccgcga aattgtgact
       61 tttccgctat ttagcgatct tgttcagtgt ggctttcctt caccggcagc agattacgtt
      121 gaacagcgca tcgatctgaa tcaactgttg atccagcatc ccagcgcgac ttacttcgtc
      181 aaagcaagtg gtgattctat gattgatggt ggaattagtg acggtgattt actgattgtc
      241 gatagcgcta ttaccgccag ccatggtgat attgtcatcg ctgctgttga cggcgagttt
      301 acggtgaaaa aattgcaact acgcccgacg gtacagctta ttcccatgaa cagcgcgtac
      361 tcgcccatta ccatcagtag tgaagatacg ctggatgtct ttggtgtggt gatccacgtc
      421 gttaaggcga tgcgctgatg tttgccctct gtgatgtaaa cgcgttttat gccagctgtg
      481 agacggtgtt tcgccctgat ttatggggta aaccggtggt tgtgctatcg aataatgacg
      541 gttgcgttat cgcccgaaac gctgaggcaa aggcgcttgg cgttaaaatg ggcgatccct
      601 ggttcaaaca aaaagatctg tttcgtcgct gtggcgtggt ttgctttagc agcaattatg
      661 agctttacgc agacatgagc aatcgggtga tgtcgacgct ggaagagcta tcgccccgcg
      721 tcgagattta cagtattgat gaggcattct gcgatctgac aggtgtgcgt aattgtcgcg
      781 atctgactga ttttggcaga gaaattcgcg caacggtgct acaacgtacc catcttactg
      841 ttggtgtggg gatcgcccag accaaaacgc tggctaagct tgccaatcat gcggcaaaaa
      901 aatggcagcg gcagacgggt ggggtggtgg atttatcaaa tctggaacgc cagcgtaaat
      961 taatgtctgc tctccccgtg gatgacgtct gggggattgg acggcggatc agcaaaaaac
     1021 tggacgcgat ggggatcaaa accgttctcg atttggcgga tacagatatc cggtttatcc
     1081 gtaaacattt taatgtcgtg ctcgaaagaa cggtgcgtga actgcgcggc gaaccctgtt
     1141 tgcaactgga agagtttgca ccgacgaagc aggaaattat ctgttcccgc tcgtttggtg
     1201 aacgcatcac ggattatccg tcgatgcggc aggccatttg tagttacgct gcccgggcgg
     1261 cggaaaaact tcgcagcgag catcaatatt gtcggtttat ctccacgttt attaagacgt
     1321 caccatttgc gctcaatgaa ccttattacg gcaatagcgc gtcggtaaaa ctgctgacgc
     1381 ccactcagga cagcagggat atcattaacg ctgctacgcg atctctggat gccatctggc
     1441 aagcgggcca tcgttaccaa aaagcgggcg tgatgctggg ggatttcttc agtcagggag
     1501 tcgcgcagct caatttattc gatgacaacg caccgcgccc cgggagtgag caattgatga
     1561 cggtaatgga tacactgaat gctaaagagg gcagaggaac actctatttt gccgggcagg
     1621 ggatccagca acaatggcag atgaagcgag ccatgctttc accacgttat acaacgcgaa
     1681 gttctgattt actgagggtc aaataaatat agcggcagga aaaaagcgct cccgcaggag
     1741 cgccgaatgg attagcgacc gaacagatca cgttttttcg ctttaaacgg ctgggaaatc
     1801 accaccagca ctgcgacaat caggtaagcg ataaaaatac cgagcagcca ctgcggcatt
     1861 tccagaccta aaaaatccca ctgacgctcg gcgcaatcgc cagaggcgac aaacacttgc
     1921 ggcacccact tatccagcgg cagccattcc gggaaacgaa ccataaaatc acaggtggca
     1981 aacggcgaag gatagagctg aagcatggtg tgctcgtaag ttaactgcac accgcggaac
     2041 gcactataca accagataac catcgctaca taacgcagcg gagttttcgg ggcgatcgcg
     2101 ccaatcagcg cagcacccag aacgccgaat aacgcgcagc gttcataaat acagagcacg
     2161 caaggtttca gtaacatcac atgctggaac cacagcgccg tcagttccag tgccagagca
     2221 gtaaacgcca tcaacagcca cgcgccccgg ccttgtgaac attggttcaa aaatcgcaac
     2281 ataatcattt ccctgcaata tgcatagagt gcgcagttta aaccaattca ttcgctgcgc
     2341 caccaggagg cagcaaaaat aggacgcaat tggacaatta tcgggcgaaa aggcaaaccg
     2401 ggcatttata tgcccggtaa gttgttatca aagcgttgct atccagccca tttgcataaa
     2461 ccattcggtt acaggggcaa gcgtaaactc gacgcagagc aagccgacga gtgtcaggac
     2521 gagggtgtaa ggcagggcca tccacaccat gcggccataa gagaggcgaa tcaatggcgc
     2581 gagtgcagag gtcagcagga acaggaacgc agcctgaccg ttcggcgtag cgacggaggg
     2641 cagattggta ccggtattaa tggcgaccgc cagcagctcg tattgcttca acgtgatagc
     2701 gccactttcc attgccgctt tcgcttcgtt gatataaatc gtccccacga agacgttatc
     2761 cgaaatggat gacagcagac cgttgaaaat atagaacagc gacagctgag catgttccga
     2821 tgcctgcaac acaaactgaa taattggcga aaacagttgt tggtcgataa tcaccgcgac
     2881 taccgagaaa aacaccgtca acagtgcggt gaatggcaga gattcggtga aggctttacc
     2941 gatagcatgc tcatcggtga caccggtcaa tgatgttgcc agaataatga ctgacaaacc
     3001 aatcaagcca acttccgcca gatgcaacgc cagcgcagtc accagccaga cgccaataat
     3061 cgcctggaca atcagacgga ttttatcctg acgggtacgc tggtggcggc tttgatcgtc
     3121 aaactgttgc aacacttcgc ggactttctc cggcagcgtt tcaccgtagc caaaccaacg
     3181 cagcttctct accagcaggc aggttaacag gccacaaatc agaaccggaa cggtcaccgg
     3241 cgacatgcgc aggaagaaat cgccaaaatg ccagccagcc gctttagcga tgatcaggtt
     3301 ctgtggttcg cccaccatgg tcattacgcc gcctaatgcg gtgccgacac cggcatgcat
     3361 catcaggcta cgcagaaagc cacggaactg ttccagaacc actttgtaat gcttgtcgat
     3421 atgactatcg tcttgcaggt cggtgtcttc ggtacgggaa gaggctacgc ggtgataaat
     3481 accataaaaa ccgactgcaa cgctgatcac caccgccacg acggttaagg catcgaggaa
     3541 cgcggagagg aacgcagccg ccacgcaaaa agagagcgac agcagcattt tggagcgaat
     3601 gcttaacagc aaacgggtaa atatgaacag caacagctgt ttcataaaat agatacccgc
     3661 caccataaac atcagtaaca gcaagacttc aagatttgcc gccacctctt cacggacgtg
     3721 ttccgcgctg gtcatgccga tgaataccgc ttcgatagcc aacagaccac cggggagcag
     3781 cgggtagcat ttcagggcca tcgccagagt gaaaataaat tccgctacca gcaaccagcc
     3841 cgcgacgaaa gggctgatga ggaaaattaa cgggtttacg attaagaaaa tgatgagggc
     3901 gagtttgtac cagtcggggg actggcccaa aaaattgcgc catagcgcgc ggccccagga
     3961 gatctccatg atggtttccc ttaccttaca aataatcaat gatgttttta tgtttaaacg
     4021 caaagcttaa cggtcagtca ggagtgaggc aagtcttgat agtcaagggg aaagaaatgc
     4081 ggaaaatgaa gccttgatcc ctttttcttc tttttgtctg ctatcagcgt agttagccct
     4141 ctggtatgat gagtccaact ttgttttgct gtgttatgga aatctcacta tggtcattaa
     4201 ggcgcaaagc ccggcgggtt tcgcggaaga gtacattatt gaaagtatct ggaataaccg
     4261 cttccctccc gggactattt tgcccgcaga acgtgaactt tcagaattaa ttggcgtaac
     4321 gcgtactacg ttacgtgaag tgttacagcg tctggcacga gatggctggt tgaccattca
     4381 acatggcaag ccgacgaagg tgaataattt ctgggaaact tccggtttaa atatccttga
     4441 aacactggcg cgactggatc acgaaagtgt gccgcagctt attgataatt tgctgtcggt
     4501 gcgtaccaat atttccacta tttttattcg caccgcgttt cgtcagcatc ccgataaagc
     4561 gcaggaagtg ctggctaccg ctaatgaagt ggccgatcac gccgatgcct ttgccgagct
     4621 ggattacaac atattccgcg gcctggcgtt tgcttccggc aacccgattt acggtctgat
     4681 tcttaacggg atgaaagggc tgtatacgcg tattggtcgt cactatttcg ccaatccgga
     4741 agcgcgcagt ctggcgctgg gtttctacca caaactgtcg gcgttgtgca gtgaaggcgc
     4801 gcacgatcag gtgtacgaaa cagtgcgtcg ctatgggcat gagagtggcg agatttggca
     4861 ccggatgcag aaaaatctgc cgggtgattt agccattcag gggcgataat cccttccgtt
     4921 taaagagcaa acccctcaaa cgaggggttt tttgttgttt ttacagattt cccattcttg
     4981 gcgggcaacg ttccagcaac tcgatgctgc cgtcttcgtt ttgctgttcg agcatcacat
     5041 caaatcccca caggcgatgc acatgcttca ggacttcttt gcgcccccga tccagcggtg
     5101 cgcgattatg tggaatataa cgcagcgtca gcgaacggtc gccgcgcaaa tccacgttcc
     5161 agatctgaat attcggctcc agattactta agttatattg cgacgataac cggttacgga
     5221 tctcccgata accttcttca ttatgaatag cggaaatctc cagataatta tgccgatcgt
     5281 catccagcac ggtgaagaag cggaaatcac gcatcacttt cggtgacagg aactggctga
     5341 taaaactctc atctttgaaa tcacgcatcg cgaaatgcag cgtttccagc cagtcggaac
     5401 cggcgatatc cgggaaccag tatttgtctt cttccgttgg cgactgacaa atccgtttaa
     5461 tatcctggaa catggcgaac ccgagggcat acgggttgat gccgctgtac cacgggctgt
     5521 tatagggggg ctggaagacc acattggtgt ggctgtgcaa aaactccagc ataaaacgtt
     5581 ccgttacttt cccttcatca tacagatggt taaggatggt gtagtgccag aaggtcgccc
     5641 agccttcgtt catcacctga gtctgttttt gcggataaaa atactggctc accttacgca
     5701 caatacgcag gatttcacgc tgccatgatt ccagcagtgg cgcatttttc tccataaaat
     5761 agagcaggtt ttcttgtggt tcggacggat agcggcgcgc ttcagcaacc gttttctctt
     5821 cctcgcgctt cggcagggta cgccagagca tattgacctg actttgcaga tactcttcgc
     5881 gacttttctg ccgggctttc tcttcttgca gcgagatttt ttgcgggcgt ttgtaccggt
     5941 ccacgccgta gttcatcagc gcgtggcacg agtccagaag ccgttctact tcatcaacgc
     6001 cataacgctc ttcgcactcg gtaatatatt tacgggcaaa aatcagataa tcgacaatcg
     6061 aactggcgtc ggtccagcta cggaataagt aattgttttt gaagaaagag ttatgcccat
     6121 agcaggcatg agccatcacc agcgcttgca tggtaatggt gttctcttcc atcaggtaag
     6181 cgatacacgg gttagagtta atgacgattt cataggccag tccttgctga ccgtgcttat
     6241 acagccgttc agtctcgata aactttttac cgaatgacca gtgcggatag ttaattggca
     6301 tgccgacgct ggagtaggca tccatcatct gttctgaggt tatcacttca atctggtgcg
     6361 ggtaggtatc cagccggtag agtttcgcca cccggtctat ctctgccaga taaacatcca
     6421 gcaggtcgaa cgtccagtcg ggtccatcgc tcaaacgtgt ggtgtcctta ttcatagaat
     6481 cgatcgtcgc catacgcgca cctcattgtt gtcggcgctc tctgtgtgga gcacctcatt
     6541 tcaagcatag aacacctgtt aaaaaccgcg tcgccggaga atttttttct ttgcgatttc
     6601 ttattatcag agtgccacta atccgcttct gaacggaatt ttatgctgga taaaaagggc
     6661 gttcagcagg agatactaaa gacgccatat tgccgcagag tcagggagat gtgagccagc
     6721 tcaccataaa aaagccgtat gttgaataat attttcaact gagttatcaa gatgtgatta
     6781 gattattatt cttttactgt atctaccgtt atcggagtgg ctatgcgagt tgtcatactg
     6841 ggaagtggtg tggtaggcgt tgccagcgcc tggtacttaa atcaggcagg acatgaggtc
     6901 accgtcattg atcgggagcc gggggccgcc ctggaaacca gtgccgcgaa tgccgggcaa
     6961 atctcccccg gatatgctgc accgtgggcg gcaccaggtg tgcctttaaa agcgattaaa
     7021 tggatgttcc agcgccatgc gccgctggcg gttcgtctcg acggtacgca gttccagttg
     7081 aaatggatgt ggcaaatgtt acgtaactgc gacaccagcc actacatgga aaacaaaggg
     7141 cggatggtgc gtctggcgga atacagccgt gattgcctga aagcattgcg cgccgaaacc
     7201 aatattcagt atgaagggcg tcagggtggg acgctgcaac tgttccgtac cgaacaacag
     7261 tatgaaaatg cgacccgcga tatcgccgtg ctggaagatg ccggcgtacc gtatcagctg
     7321 ctggaatcca gccgcctggc ggaagtggag cccgcgctgg cagaagtggc gcacaaactg
     7381 acgggcggcc tgcagttacc caatgatgaa accggagact gtcagctatt tacccagaat
     7441 ctggcgcgga tggcggagca ggcgggggtt aaattccgct ttaatacgcc cgttgaccaa
     7501 ctgctttgcg acggcgagca aatctacggc gtgaagtgtg gcgatgaagt gattaaggcc
     7561 gatgcgtatg tgatggcgtt tggttcttac tcgacggcga tgctcaaagg cattgttgat
     7621 attccggtgt atccgctgaa aggctactcg ctgaccattc caattgcgca ggaagatggt
     7681 gcgccggtat ccaccattct tgatgaaacc tacaaaatcg ccattacccg tttcgataac
     7741 cgcattcgtg ttggcggaat ggcggagatt gttggtttta ataccgagct gttgcaaccg
     7801 cgtcgtgaaa cgctggagat ggtggttcgc gatctctatc cacgcggcgg tcatgtcgag
     7861 caggcgactt tctggactgg tctgcgcccg atgacgccag acggcacgcc ggttgtcggg
     7921 cgtacacgct ttaaaaatct gtggctgaat accggtcacg gcacgctcgg ctggacgatg
     7981 gcttgcggtt ccggtcagtt gttaagcgat ctgctctctg gtcgcacgcc agcgatccca
     8041 tatgaggatc taagcgtagc gcgctacagc cgtggattta cgccatcacg tccgggccat
     8101 ttacatggcg cacacagcta aggaaacgag atgacccgtc cgatacaggc cagcctcgat
     8161 ctgcaggcat taaaacagaa tctgtccatt gtccgccagg ccgcgacgca cgcgcgcgtc
     8221 tggtcggtgg taaaagcgaa cgcttacggg catggtattg agcgtatctg gagcgcgatc
     8281 ggggccaccg atggctttgc attgcttaac ctggaagagg caataacgtt acgtgagcgc
     8341 ggctggaaag gaccgatcct gatgctggaa ggatttttcc atgctcagga tctggagatt
     8401 tatgaccagc accgcctgac cacctgcgta cacagcaact ggcagctcaa agcactgcaa
     8461 aatgcgcggc taaaagcacc gttggatatt tatcttaaag tgaacagtgg gatgaatcgg
     8521 ttgggcttcc agcccgatcg cgtgcttacc gtctggcagc agttgcgggc aatggcgaat
     8581 gttggcgaaa tgaccctgat gtcgcatttt gccgaagcgg aacatcctga tggaatttcc
     8641 ggcgcgatgg cgcgtattga gcaggcggcg gaggggctgg agtgtcggcg ttcgttgtcc
     8701 aattcggcgg cgactctgtg gcacccggaa gcgcattttg actgggttcg gcctggcatt
     8761 attttgtatg gcgcttcgcc gtccggtcag tggcgtgata tcgccaatac cggattacgt
     8821 ccggtgatga cgctaagcag tgagattatt ggtgtccaga cgctaaaagc gggcgagcgt
     8881 gtgggctacg gcggtcgcta tactgcgcgc gatgaacagc gaatcggcat tgtcgccgca
     8941 gggtacgccg acggttatcc gcgccacgcg cctaccggta cccctgtttt agtggacggc
     9001 gtgcgcacca tgacggtggg gaccgtctcg atggatatgc tagcggtcga tttaacgcct
     9061 tgcccgcagg cgggtattgg tacgccggtt gagctgtggg gcaaggagat caaaattgat
     9121 gatgtcgccg ccgctgccgg aacggtgggc tatgagttga tgtgcgcgct ggcgctacgc
     9181 gtcccggttg tgacggtgta acttgttgta agccggatcg gaggcaacgt cttctgggtg
     9241 caaaaaaatc atccatccgg ctggtcagca actgtagttg ttaatgtgac agagccattg
     9301 cccatgatag tgtccattaa aaggatggac actatttccc cggaacctga actcaccgca
     9361 caggcgttct acataaaacg cttacgcttc attgttgact cgaactcgac ttcagataaa
     9421 tcacgcttta cccttgatgg agcctgtaca tagatttgtg taattgcctg attttgatat
     9481 gttcaattca acatcaaatg aaggttaaat tatggacgac aaacaattgc aggctcaggc
     9541 tgcgttcagc aaagcatcgc aaccggcgat agatgcttca ttaaatttaa gattcagctt
     9601 cctcttcagc cacccgtacg ccaatcttca acacttcatt atcttctttc tcggccaccg
     9661 tccagatcat cccggcaaac tctacctggt caccgacaac cggtgccgcg cctaacaact
     9721 gctggacaat ttcacccagc gtttgctgct tatcacgata ttctcgcccg tcttccaggc
     9781 catatatcag cgcaacatca gcatatttgg cgctggcttc gagaatgaag tcaccaaaga
     9841 agcgttgatc cagcgcgacc ggcggcgact ggctgaacag tttaccgagc gccggaagat
     9901 cgcgttcccg accaattaca cacaacacat cgccttcgcg cagtcgggtg ctgccggtag
     9961 gatgaagcaa ctggttatca cgaaacagtg ccgcaatacg cgtctctttt ggcatatgca
    10021 aatcgcgcag tgccgcgccc acgcaccatt tatcggcact caattgataa acaaactgct
    10081 cccacggatt ttccggatga atatccaggc caacgcgtga caccggacgt cccactggcg
    10141 gaaccaccac tttggctttt ttagccgccc acgagagtga tgttccctgc aagagcagtg
    10201 aaaccagaac cacaaagaag gcgacattaa agaacagacg tgcattctcc agccccgcca
    10261 tcatcgggaa cacggccagg atgattggca ccgcgccgcg taatcctacc cagctgataa
    10321 acacgcgctc acgcagattg aaaccgcgga aggggagcaa tccagcaaat accgaaaggg
    10381 gacgggcgaa gaatatcatc catgcggaca aaatgagcgc cggaatggca ataggcagca
    10441 gatcgcttgg gttaaccaac agccccagca ccaggaacat ggcgatttgc gccagccagg
    10501 cgaggccgtc gaaattttgc aggatgccgt agcggttgcg aatagggcga ttacccagca
    10561 gaaaaccgca cagatacacc gccagaatac cgctaccttc cagcgcagta gttaatgaga
    10621 aaatcagaat accgccactt aatgccagca atggatataa tccggcgggc agggcgatgc
    10681 ggttgatcat ttgcagtagt aaataaccgc cgccaagacc tattacaatg cccagaccaa
    10741 attgttgcag aatatcgaca atgaacatcc agctaatatt gctctcatga tgctggatca
    10801 tcgcaattag ggtaatcgtc agaaagaccg ccattggatc attactgccg gattcaattt
    10861 ccagcgtcga gccaacacgt tcgttaagcc ccttaccacc cagcagagaa aagaccgctg
    10921 cagcatcggt agagccgacg atagcgccga ttaataagcc ttcaatcaaa tcaagattaa
    10981 acagccacgc cgccatcatg ccggttaaac cagaggtgat aagcacgccc agcgtcgcca
    11041 gcgacagtgc cgatcctaac gccacacgaa aggaactggc ctgagtgcgc atcccgccgt
    11101 cgagcaaaat aatcgccagt gccaggttac ttaccatgta ggcgaagggg taattatcaa
    11161 acgggatacc gccgacgcca tcgactcctg ccagcatgcc gatcgccaga aaaataacca
    11221 gaataggaat gccaagacgg gaagaaaatg aactaagtaa tatactgctg gtgacaagga
    11281 tggatcctaa gatgaaaagg ctaattattg ttgtggcatc caacggtcgg ttactcctga
    11341 ttacgctgtc tcttatataa accctaccat attagcggca gagacagcgt tttacttagc
    11401 cctgaagcgt gattttttta cattttaaga acaggatgac cgctaatcgt caactgagtg
    11461 ccttcccggg tgttattcag aatggcatgt gcgcccaacg gcagcgtaac cgtgcgttgt
    11521 tcatgaccaa aatcgaggcc ggtaatgagt ggaatcgaca ggcgggaacg caaaaacgcg
    11581 tacactgact ccaggttgta acctgcgtca taatcattgg gcgtgctgcc gctaaagcta
    11641 ccgagaataa tcgccttctg acgtggcaaa attcccgcat gatagagctg caacagcata
    11701 cgttcgaccc ggaaagggtg ctcgttaata tcttccagca ccagaatacc gttctcaatt
    11761 tttggcatcc acggtgtacc gatcagtgaa atcagcatcg caagattgcc tccccacaac
    11821 gtgccttcgg cccgacatgt cgggccttcc ccttgccatt caatggtgaa ggtttcattg
    11881 cgtaacgcca gccagaaatg gtgctcggta aaggcgttca gttcatccgc gccaaagttt
    11941 gctaccagca tggggccgct aaaggtgatg acattgccat gcgccagaag accgcactga
    12001 atggcggtaa aatcgctatg tccgcaaatg agcaacgggt catgttgttg gcgagccacc
    12061 agtgcctgcc agtcaatatc tgccagtaaa cgactggcac cgtaaccgcc gcgtacagcc
    12121 agcacgatgg tgttgggggt agtcagtctg gcaagggaat tgagatcttc cagacgctct
    12181 gtttccgtac ccgcaaaacg ctcacaacga cgggcaataa cctcgacgtt attgacttga
    12241 tgccccgcgt cggtaaggcg ctggatacca cgcagcgcgg cgtgctgttt aatgcagtaa
    12301 cccgatgggg caattaagtg aaacagagac atggcaattc cttgctgaca acagaaacga
    12361 aatgtatatc atgccgctta ggtgtgccgt tgtcacctca acggcgattc caggctataa
    12421 ggatagaaga agtgaaattg agatggtttg cctttttgat tgtgttatta gcgggttgtt
    12481 catcaaagca tgactatacg aacccgccgt ggaacgcgaa agttccggtg caacgtgcga
    12541 tgcagtggat gccaataagc cagaaagccg gtgcagcctg gggcgtcgat ccacaattga
    12601 tcacggcgat tatcgctatc gaatcgggtg gtaatccgaa cgcggtgagt aaatcgaatg
    12661 ccattggttt gatgcagtta aaagcttcaa cctccggacg tgatgtttat cgccgtatgg
    12721 gctggagtgg tgagccgacg accagcgagc tgaaaaatcc agagcgtaat atttcaatgg
    12781 gggcggctta cctgaatatt ctggaaaccg gcccgctggc aggcattgaa gatccgaagg
    12841 tactgcaata tgcgctggtg gtgtcatacg ctaacggggc aggtgcgctg ctacggactt
    12901 tctcgtcaga tcggaaaaag gcgatcagca aaatcaacga tttggatgct gacgagttcc
    12961 tcgaacacgt agcgcgaaat caccctgcgc cgcaggctcc gcgctatatc tacaaacttg
    13021 agcaggcact ggacgcgatg taaatcagtc gcgcactttg tccgcttttt cccgggcttc
    13081 tcgctcgaga gagaaaataa tccgctgtaa ttgccgctcc accgtcgggc tgacgttaag
    13141 aaaacggaag ctcagacggg gagtggtgat ggtttcattc ttgccatcaa tcactttgcg
    13201 ctcgctgatg gagattaact gggcgtcaaa gtgaaaaaca ccccattgcc ccatgttgac
    13261 ttcaatctga gcgaagcgca tgccttcttg taattcggca ggctttgctg tttccagtaa
    13321 tgcgcccatg ccgcctaacg acaaatcata caggcggaaa cgtaacgtac tgttatccgc
    13381 cagtttggtc tggcaaaaat aaggcggatg gagtggggcg gagatgcgga aatatcggcg
    13441 tcgttgtaca aaccataagg tgggaggcgg tacggtaata aatgccggaa gctgcaagta
    13501 ttcactctgc tgtagttgtt caacagtaaa ctcgactttc gcaccctgag tttcggcggt
    13561 aatggtaatg tgctgtgcct ttagcacggc gatgttgtct tcggcttgac tgccgaaatc
    13621 cagcaccagt ttatccgggg ttattgccag taatttgctg atcagctgcc cgccattcca
    13681 actgagacgc aaaggaattg cggctttgtg caaatcgcgt aacacgccca ggacggctaa
    13741 cggattttgt ttcaggaact gctcatggta atgactcacg cggaaaaact cctgactgac
    13801 aaactgtctt tggtttatcg gtcacagtta acaaaactta atacaaatgc gtgaatattt
    13861 tttacatgtt gttcttaaat cagccgacat acgcccagca tcgatcccgc ccttgcctat
    13921 acttagagcg ttgatgtaag catttcttgc gtccgattca tcgaaacgag ggcctgaaca
    13981 tgggaattat tgcctggatt atttttgacc tgatagccgg cattatcgcc aagctaatca
    14041 tgccggggcg tgatggtggt ggatttttcc tgacctgtat tctcgggata gtcggtgcgg
    14101 tggtcggcgg ctggctggcg accatgtttg gcattggcgg ctccatcagt ggttttaatc
    14161 tgcacagctt cctggtggcg gtggtgggag ctattctcgt tctgggcata ttccgcctcc
    14221 tgcgaagaga ataagatttt cataaggcgg atagcgatac agatgccgct atccgctttc
    14281 acatcagaac gtatactcga cacctgcttt acgggtgaaa aaaatcaata tagcacttcg
    14341 atatccgata aagtcggttc ccggtaacaa caacagaatc cttttttaat tattgtttcg
    14401 ttgtttttgg tgtgattcag aaaataaata ttttagacag tagccagtca ggcgttaaaa
    14461 atggggcgga tagtgaggcg gttttggctg cgcttactga acatttagaa ttgatcaatc
    14521 cttctggcag attaagccaa aatacccgtt cggcaatgct tcagttacgc gaagaggaat
    14581 ggtctgaatt ctttttttgg ttgctaaatt ctctggagtg tctggattat gtgattatta
    14641 atttaactcc agaaagcaaa aaaacgttga tgagtgaaca ccgtaacaat attcaggtag
    14701 caattgatgc tttatatagc caacgtcggc gtaaatcgcc gggtgatgaa agtgaaacac
    14761 ttacccgtag aaatgacgct atcttcggca accacgtatg gcaaacattt gcgcaatact
    14821 tcccgccagg acttgaaaaa ccgtctgtgt agaaaaaacc atagctatgg tgttatctgc
    14881 cgacaacgcc atccggagaa gccgaatgac gttgtcggag taagcgctgg ttaaggtgtg
    14941 ggttgtgcct ctttggttga gggttgcgtc gttgctgact taacggtcgg acgcgtcgcc
    15001 ggaacattgt cacacggttg ctctttcggg cagatcaaat ccagcatttt cagcgtcacg
    15061 ccattggtcc agccaaagcc atcctgtaat ggatattcgc caccgccgcc ccccgttccg
    15121 gtggtgctga catcatattt ttccaccagc tttttctccc ggtcataggt gtgctgaaca
    15181 ttggtcagga agtgccagct aatgtccatc gccacctctt tttgcccgta gttttgtaat
    15241 ccttctgtcg cgacccactg taacggtgcc cagccatttg gcgcatccca ttgttgccca
    15301 cttttcaccg acgtggtgtt caggccgccg ggttgcagca gatgtgtttt cgtcgccgtc
    15361 gccattttgt tggcgcgatc tttcgctgcc gcattgacgt acagcgggaa cagggcggcc
    15421 gcggttaact gattgcgcac tttatgactt ttcaggtcgt aatcggcata ccagccttgt
    15481 tgatcgttcc acaggtattt ttcgatccct ttttgacggg catttgccag cgtttcgtac
    15541 tggtttgcca tcgcgttatc tccggcagct ttgctggcgc gggcgaggat tttttccatt
    15601 ttaaacatca ggctgttcag atcgaccggt acgatgctgg tggtgcgtaa ggtatttaac
    15661 tgctgcgggt tgtccatcca gcgcgagctg aaatcccagc cagacgcagc ggcagagcgc
    15721 aggtcgcggt aaatttcagt ggcaggtcga ttcggattgc ttttggcggt ggcaatatct
    15781 tccacccatg actctggtcg tggcgtatcg cgatcgtccc agtagcggtt gagaagggta
    15841 ccatcctgaa gtttgacaac gcgtttttcc tgttgtccgg cttgcaggtt ttcaacaccg
    15901 tccatccagt aagcatattc tttttgcatt tgcggcaggt attgcttcaa cgcggcatcg
    15961 ccttcatgct gcgccagtaa ctctaccatc agggcaaaga agggcggttg cgagcggctt
    16021 aaatagtaac tgcggttgcc gttgggaata tgaccgtaag tgtctatttc atgagcaaaa
    16081 ttggccacca tatccgcgac tttatcccag tgaccgcttt cggcaagtcc taacatggtg
    16141 aagtaactgt cccagtaata tacctcgcga aagcgtccgc ccggcacgac ataaggttcc
    16201 ggcagcggta acagagaatc ccatttttcg gtgttttcgg tagaacgcgt taataccggc
    16261 caaagtccgt caatatgttc gcgcagtgac tgcccctctg gcggaacata tttctcacct
    16321 tctttcggca gggtgaaatt gacgttaacg aaatggcgca gatcaaatcc gctctggttt
    16381 tgctgcatcc gataatcagc aaggatcatc agcggatcgc tgttcggcac ggcatcggca
    16441 aaggtttttt ggtccggaaa aagtttggcg ttttgcacat cattaaacag cggccctaat
    16501 aaaatatcag gcggctgtgg tgttaccggt gtttcttctg cctgcaccga tagcgcagcg
    16561 aaacacaaaa agatacaggc tggaattaac gccatttttt gcgggcgaga aggtgcgggg
    16621 gatttcatca atcattctcc tttggcgaaa ccgaataaaa cggtattcaa gtatcagaaa
    16681 accttagttc aggatcgcac tagctgcatg atcgaaatct cattctgcga actgtcaggc
    16741 attttagaaa agggaattaa agggataaat aacggcgaaa tagagtgatc aaataacgtc
    16801 tgtttattag ccagccagcg gcgttgggtt cgtgattagc gaagaaaaat catcataaat
    16861 tggtgaaaaa tataacaggt agttaaaaac cattagtgct gagtaaattg ccggatgaca
    16921 tcagaacgat gccatccgaa cagtggctta accctgacgg ttgaaacgtt gcgttttaac
    16981 gtccagcgtt agcgtttctt ctggttgtat cgcatacagt ttctcaccct gctggcaaat
    17041 ccagccaatc cccagttcac gggcgattag ggcgctgtgg gataccggac ttccggcgct
    17101 aaggcagata ccttttacaa ccgccggatc cagttgcagt actgtggaag gataaatgtt
    17161 ctccgccagt agaatagttg gcgagttaaa ctgcgggagt tcttctttcg tttgggtcag
    17221 gtggaccagg gtgcgatgca gaagatcgtc cacatcaata tagcgagctt gtagatattc
    17281 atcatccagt tgctggtatt gctggctaag ttctttaaga acttgctgcc aggcatattc
    17341 tgccgtgcaa tgttcatgct gaaggagttc gcttgccgcc gccagcagtt ccggatcatc
    17401 taacagtgta tggtgaccag aaaagattgc ggcaatatcg tcaagcccgc tggcttctgc
    17461 tttcgctgtt aacgtcatca gatctaataa cgtgaagtca atagcctggc gtaatcgatc
    17521 ttgttcttct tccacggtca gggttgattt tgcctgtacc gtacataaaa ctggttgata
    17581 ataaaaggct ttacccgaaa caggcggaac gggacgcaga gtaggtggag cgacttcctc
    17641 cgtttcacca aagttatctt cagccagctg acggaaagcg atcagtgcct cttcagcttc
    17701 tggccctttc gcaatcaggc gcagcgtatc gttatagcga acttgtagta acgcaatctg
    17761 gttaatactc tctggtgtga cgcatttgcc gtttttttcc agcaacatat cggcattaaa
    17821 tgtcgataag gtataaacca gccgggaggc cggacgtaca tgcaggccgt tacggttttt
    17881 tatgaccacc gccagagaac gggcttcttc atcgtacgca ggacatgtgt cagagatttc
    17941 agtgtcggag gacggtaaac ccagttgttc acgtttggct tccagcgcat gcatggcgtc
    18001 aaagataact ttgtcgatat ccgcccccga ggccgcgctg accgttgctg ccagtgtacc
    18061 ttcgaccaac ggcgcagcac acaaacgtac ttttgcggcg atctcgggag ccagcaattc
    18121 cagcgcagtt tcagcactca ataatgcgct acccatatcc atcatgacca gcacatggtc
    18181 ggcatcagca acagattcga tggcctccat cactttgacg gcatcggtac caatgggatt
    18241 ttgtggatcg tcaattcccg cggcaatggc gattttacaa ctatcactca ttaacatctg
    18301 acgggctaat tcaccgacac cttctcccag tcggctgcta tgtgaaacta tgaccaggtt
    18361 taccatcacc aattccttac tcttttgcgg ctaacgccaa catttgcatc ataaacatca
    18421 ccgaggtcgc gccgggatcc tggtgaccaa tactgcgttc accgagataa ctggcgcggc
    18481 ctttgcgggc ttgcatcgta atcgtacttt gtgcagcgga ttcggcgatg ctactggcag
    18541 cttcgagcgc caccggaaca gagagatttt gctcgctgga ctgacgtaac gattccacca
    18601 ccggcaccca cacatcacac atggttttat cgccaggttc ggctttcccg cgactgatta
    18661 cgccgtccgc gccatcgcgg aacatctgat aaagctcttc cagtgtcagg ctttgccgtg
    18721 cctgggtcgc ctgtgcggcg cggataaaga aggtaccgaa cagcggacca ctggcaccac
    18781 cgacgctgga aagcagcgtc ataccggtat tcttgagaat gaaaccgata tctttatctg
    18841 cgatagcagg gagtttttcc accactttgc taaagcctcg gttcatattt agcccgtggt
    18901 cagcatcgcc aatttcgcga tccagtccgg taagatactc gctctcggtg ctgaaaatat
    18961 cgccacaacg agtgagccag ttaacaattt gagttctgct cagtgacatt gctttctcct
    19021 tatttacccc agttaagggc cggggtgtgg accggggcgt cccagagtgc cagcgtttcg
    19081 tcatcaactt tcagtaaggt gattgagaaa ccggtcatat ccagtgaggt gcagtacgcg
    19141 ccaattaaat tacgttcgat agtcaatccc gcttgctggc aacgtgtggt caggcggtta
    19201 tagacgccgt acagctcaga aagcggagtt gcgccaagat tgttaaccag cgcaatcacc
    19261 cgatcgccag actggagcgg ttgtttggtt tgttgttctt cctgccaact gccttgttga
    19321 taatcccaga aacgcaaagt gcgatggtat gagccattta ccagcagggt gtcgaacatt
    19381 tcatcgacgg tttgatcaag ggaagagaag gggcggcggt caatacccgg ctcaccatga
    19441 atgccgacgc caaactccat ctcattatcc gccagggtaa aagaaggttt gcccgcggca
    19501 ggaacggtac aggcaccgag agcgatacct attgagtggc cttgattatt cagcttacgc
    19561 cccagttccg cacaggcgtc cagtgagtcg ccacgctccg ccgctgcgcc tacgagtttt
    19621 tcaattaata cggtgttggc aacgccgcgt cgcccggcag tataaagact gtcttttacc
    19681 gcaacgtcgt catcaatgac cacagtggtc acttttacgc cgctatcgtg cagtaactcg
    19741 gtcgctgttt caaagttaag aatatcgccg gtgtaatttt tgataatcaa cagtacacct
    19801 tcgccgccat caacttgcat ggcgcattca aagattttat cgggcgtcgg tgaggtgaaa
    19861 atttcgcccg gacaggcccc cgaaagcatc ccctgaccga tataaccaca gtgcatcggc
    19921 tcgtgtccgc tgccgccacc cgacagcagg gcgacttttc ctgcaacagg ggcatcagct
    19981 cgggtgacat acaccggatc ctgatgcagt gtcagcgatg gatgcgcttt cgccagtcct
    20041 gccagttgtt cgtccagtac gtcttgcaca tcattgatca attttttcat tattttgctc
    20101 cagcaattac ggtagggcat ggatgatgtt caacgacacg gcgaccactg actgccgatg
    20161 aatccattgt gcatcaggca agggaaaaga aaattagccc aaattatgtt tcatagtgaa
    20221 acatatgctt taatgaatgt tccatattga aacttttacg tgtattaata cttaaaattg
    20281 cgagccggaa caccttttgt cataagggat gcgggatatg agtggcgctt ttaacaacga
    20341 tggtcggggc atatctccct taattgcaac ctcctgggag cgatgcaata agctgatgaa
    20401 acgggagaca tggaacgtac cacatcaggc ccagggcgtg acatttgctt ctatttatcg
    20461 gcgtaagaaa gcgatgctga cgctcgggca ggctgcgctg gaagatgcct gggaatatat
    20521 ggcaccgcga gagtgtgcgc tgtttatcct cgatgaaacc gcctgcattc tcagccgtaa
    20581 tggcgatccg caaaccttgc agcagctaag tgcactggga ttcaatgacg gcacgtattg
    20641 cgccgaggga attattggta cttgtgcgct atcgttagcg gctatctctg gtcaggccgt
    20701 gaaaacgatg gccgatcaac atttcaaaca ggtactctgg aactgggcct tttgtgcaac
    20761 gccgttgttt gacagcaagg gccgattgac gggaacaata gcgctggcgt gtccggttga
    20821 gcaaactacc gcagctgatt tgccgttgac gttggcaatc gcccgcgagg tcggaaattt
    20881 actgctgacg gacagtttgc tcgctgaaac taaccgtcat ttaaatcaac ttaatgccct
    20941 gttagaaagt atggatgatg gcgtgattag ctgggacgag cagggtaatt tgcaatttat
    21001 taatgcccag gcggcgcggg tcttgcgcct tgacgcgacg gcaagtcagg gacgggcaat
    21061 cactgaactc ttaacgttac ccgccgtatt gcaacaagca ataaaacagg cacatccgct
    21121 caaacacgta gaagcaacct ttgaaagcca gcaccagttt attgatgcgg tgataaccct
    21181 taaaccgata atagaaacgc agggaaccag ctttattttg ttgctccatc ctgtggaaca
    21241 gatgcggcag ttgatgacca gtcaattagg aaaagtcagc cataccttcg ctcatatgcc
    21301 acaggacgat ccgcaaaccc gccgcttgat tcattttggt cgccaggcgg cgcgcagtag
    21361 ctttcctgtc ctgctttgtg gagaagaggg cgtgggcaag gcactgctaa gtcaggcaat
    21421 tcataatgaa agcgagcgtg ctgcaggtcc ttatatcgcc gtcaattgtg agttatatgg
    21481 tgatgctgcg ctggcggaag aatttattgg tggcgatcgc acggacaatg aaaatggccg
    21541 tctgagtcgg ctggaactgg cacacggcgg cacgctgttt cttgaaaaga ttgaatatct
    21601 ggcggtggag ttacagtctg ctttgcttca ggttatcaag cagggggtta tcacgcgact
    21661 ggatgcgcgg cgtttaatac caattgatgt caaagtgatt gcaacaacga ccgcggacct
    21721 cgcaatgctg gtggaacaaa atcgttttag tcgccagctg tattacgcgc tgcatgcatt
    21781 tgaaattacc atcccgcctc tgcgtatgcg gcgtggcagc attccggcgc tggtgaataa
    21841 caaattacgc agtcttgaaa aacgcttctc tacgcggctg aaaattgatg acgatgccct
    21901 cgctcgcctg gtttcttgtg catggccagg caacgatttt gaactttaca gcgtcatcga
    21961 gaatcttgct ctgagtagtg ataacgggcg cattcgcgtc agtgatttgc cggaacatct
    22021 gtttaccgag caggcgacag atgatgtcag cgccacccgc ctttccacca gtctgtcatt
    22081 tgcggaagtt gaaaaagagg caattattaa cgcagcccag gtcacaggcg gtcgcattca
    22141 ggaaatgtcg gctttacttg ggatcggccg cactacgctg tggcggaaaa tgaagcaaca
    22201 tggcattgat gcagggcagt ttaagcgccg ggtatgaaag acagaaacga tttctgatac
    22261 atcagagtga tctgtatttc attccggcgc acgctaacaa ttttcagcat cgtttaaggg
    22321 cttgtctatc ccgcacttaa aagctgaagc gatatcctcc gttgacttgc ttctgatcaa
    22381 agaggttacc ctgcgtgtaa tccgcttcga gatagaatgt gtgctgtttg ttatactgtg
    22441 cactgactcc cacgccgtta ttccagccat tacctttgaa actgtacttc tcccgggagt
    22501 tgttcaacag atattcggta tcccctgaaa actcgcggat agcgccagtc ttcacataga
    22561 cattcagctg gctgttgcct gcggtgatgt cataccccag tatcatgctg gcacgcccca
    22621 gcagcgattc gtagtgattc agatgtatat tgaggccatt actcgccttc atagtcatct
    22681 cattctggtg gctgtatgta agctgggttt gcggctctat atagaaccca taaccagtag
    22741 gggacaggtt gaacctctgc ccggcttcca gggagatgct cattccattc gcagtgccgt
    22801 tggcgttaac gccgttgttc tgactgtcca gtacgtggaa actatttttc tggcgcgatg
    22861 cttttataac gagatcgctg taaaaaccgt tttgtgccat gtaactggcg tacattccca
    22921 tgtagtctga acgtgcggta ccgtcgcctc cgctatagtc cggcgatgca tgtgttgagc
    22981 caatatacag accgacatac aacggcatta catcagagag acgtttatcc ccaccaaact
    23041 ggataccgct gtaacccatg tcaaagccgc tcagtttgcc actggcaaag gagtccaggc
    23101 ttcccccata actgcgcaac cagatattac cgtctttact ctgatttcgc aggtcaccca
    23161 tccgttgcat cagcgtacgg ttttcaacat agttcaataa gtaaccgaca ttgagataat
    23221 tgccgccagc atctgcggtc gtggtgggtt taggcgtggg agcgggttca ggcgtaggat
    23281 cggggttgac tatgggaggc tgagcgggag ctggtgtggg ttcaggatta ggagtcggtt
    23341 ccggaactgt cccggaagcg taaagctccc agttagtgcc atttttacgc acatcgtaca
    23401 gatatccccc caactcaacc tgagaagacg cgctgaacga ggccgcgccg tcagtggttt
    23461 ttaccactgt cagaacttca tttcccgttg tggcctcgct gccctggttg cggatagcca
    23521 atacgtgatt accagcacta ctcccgctga tattcaataa atccccttta ttattaacgc
    23581 cattaccctc gccaacaaca tcagcacgca taataaaggt actgttaccg ctcaggttct
    23641 ctacgtttaa tgtggcaaat gtgccggcag ttgacccgtg gctggcaaaa tcgacagttg
    23701 aatggctcag cgccagcgtg tcgagattag aattacttgt tacgttccag acgctgttat
    23761 tcattgcaac gtccagtttt ccgccattga cattatcgct gagggaggaa cctgtccaaa
    23821 ccgacccagg gtgcatatcc agattgatta gcccaccttt ggaaagaacg ctaccgttga
    23881 taagcatacg acccgaggcg ttgatgcggc tggcggcata accatcgtca tgttgcgttg
    23941 cgatggccat ctggtcgggt gtactcatat caatgaccag atcgctcgtg aggtcgatct
    24001 ggctgttggt catggcataa attcccctgg ctcctgccgc gccggtgata gccaaactgt
    24061 ctccggttat tctaccgccg ctgagagccc acaaacccag cgccagactg ccattacgat
    24121 caactgtaat atcggtattt tgcatgttga caacagccgt tgccgtctgg gccgaggcac
    24181 cataagaacc gccggaaaag atgctgtttc gttgcgctgc cgtgccagta aaattgatta
    24241 tcgcgtctga accactggtg acgaggccac cgccctgcgc ggaagaaata tggctatctg
    24301 caccgatagt ggttgtacca ccacgaactt cgacgccatt ggccgcggct ccagttacat
    24361 caacagtgag tgcattcgcg ctaacctggc caaagctcca gaggccgtga gcattatcgc
    24421 cattggtttt aatggtactg tttgttccga gatcgacaac agagtttttc tgtacgttta
    24481 tccccatggc gctgtagccc tgaacatcga ttgtcaggtc tgtagccgta aaacgcgcag
    24541 caccattggc gttattgccg ttgagaccac cgatataaac acctgtactt ccatcggtcg
    24601 tgattttact tccgcttcca agatcgacac tggtgccata gtcattgatg gttaggccta
    24661 taccgttcga gttttcaatg gtgaattgag tggctgttag tgttgagcta tgcccaataa
    24721 tgatgccgtc atcgttactc ttaatggtgc tgcctgtgcc taagtcagca tgggtatagt
    24781 caccaattaa gttaatgccg atggcagagg tttgaccaac aacatctact gtgagtcggt
    24841 tagctgtcag ggagctgttt ttgccctgaa taatgattcc ttttgcatat ccagaggcgt
    24901 cgttgacatt gacggtgaca tcattaccca ggttgatatt gccaggcgtg tttcctgctg
    24961 gggtcattac accatagagg tttcctgatg gatcggcggt atctcctgta attctgtcac
    25021 catcattaat agtaatattg gtgccatatt gacttcctgt atcagcagct atcagcaggg
    25081 gggaaaagat aattgcattc aaaccaatag cgccaaattt tatcagttga attgagggcg
    25141 aacggatttt taattcagcg agacgatctg ctttggtatt cccattgtgt tgtttgatgc
    25201 ccataccact cctatatagt acccagacta tgggtctatg gattttgtca ttttgtttaa
    25261 atcaatgaat aatatc
//
LOCUS       DAPOAV010000066        25099 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.066, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000066 DAPOAV010000000
VERSION     DAPOAV010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25099
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.066"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(91..174)
                     /gene="yohP"
                     /locus_tag="RN951_003035"
     CDS             complement(91..174)
                     /gene="yohP"
                     /locus_tag="RN951_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YohP"
                     /protein_id="HDX2528006.1"
                     /translation="MKIILWAVLFIFLIGLLVVTGVFKMIF"
     gene            398..1834
                     /gene="mdtQ"
                     /locus_tag="RN951_003036"
     CDS             398..1834
                     /gene="mdtQ"
                     /locus_tag="RN951_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001583680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug resistance outer membrane protein
                     MdtQ"
                     /protein_id="HDX2528007.1"
                     /translation="MNRDSFYPAIACFPLLLMLAGCAPMHETRQALSQQTPAAQVDTA
                     LPTALKNGWPDSQWWLEYHDNQLTSLINNALQNAPDMQVAEQRIQLAEAQAKAIATQD
                     GPQIDFSADMERQKMSAEGLMGPFALNDPAAGTTGPWYTNGTFGLTAGWHLDIWGKNR
                     AEVTARLGTVKARAAEREQTRQLLAGSVARLYWEWQTQAALNTVLQQIEKEQNTIIAT
                     DRQLYQNGITSSVEGVETDINASKTRQQLNDVAGKMKIIEARLSALTNNQTKSLKLKP
                     VALPKVASQLPDELGYSLLARRADLQAAHWYVESSLSTIDAAKAAFYPDINLMAFLQQ
                     DALHLSDLFRHSAQQMGVTAGLTLPIFDSGRLNANLDIAKAESNLSIASYNKAVVEAV
                     NDVARAASQVQTLAEKNQHQAQIERDALRVVGLAQARFNAGIIAGSRVSEARIPALRE
                     RANGLLLQGQWLDASIQLTGALGGGYKR"
     gene            1887..2648
                     /locus_tag="RN951_003037"
     CDS             1887..2648
                     /locus_tag="RN951_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDX2528008.1"
                     /translation="MAQVAIITASDSGIGKECALLLAQQGFDIGITWHSDEEGAKDTA
                     REVVSHGVRAEIVQLDLGKLPEGAQALEKLIQRLGRIDVLVNNAGAMTKAPFLDMAFD
                     EWRKIFTVDVDGAFLCSQIAARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHAL
                     GGLTKTMALELVRHKILVNAVAPGAIATPMNGMDDSDVKPDAEPSIPLRRFGATHEIA
                     SLVAWLCSEGANYTTGQSLIVDGGFMLANPQFNPE"
     gene            complement(2778..3356)
                     /locus_tag="RN951_003038"
     CDS             complement(2778..3356)
                     /locus_tag="RN951_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416640.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDX2528009.1"
                     /translation="MDLNTLISQYGYAALVIGSLAEGETVTLLGGVAAHQGLLKFPLV
                     VLSVALGGMIGDQVLYLCGRRFGGKLLRRFSKHQDKIERAQKLIQRHPYLFVIGTRFM
                     YGFRVIGPTLIGASQLPPKIFLPLNILGAFAWALIFTTIGYAGGQVIAPWLHNLDQHL
                     KHWVWLILVVVLVVGVRWWLKRRGKKKPDHQA"
     gene            3526..4113
                     /locus_tag="RN951_003039"
     CDS             3526..4113
                     /locus_tag="RN951_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014170891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIP1 family protein"
                     /protein_id="HDX2528010.1"
                     /translation="MSHVWGLFSHPDREMQVINRENETISHHYTHHVLLMAAIPVICA
                     FIGTTQIGWNFGDGTILKLSWFTGLALAVLFYGVMLAGVAVMGRVIWWMARNYPQRPS
                     LAHCMVFAGYVATPLFLSGLVALYPLVWLCALVGTVALFYTGYLLYLGIPSFLNINKE
                     EGLSFSSSTLAIGVLVLEVLLALTVILWGYGYRLF"
     gene            4287..5219
                     /gene="pbpG"
                     /locus_tag="RN951_003040"
     CDS             4287..5219
                     /gene="pbpG"
                     /locus_tag="RN951_003040"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416638.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine endopeptidase"
                     /protein_id="HDX2528011.1"
                     /translation="MPKFRVSLFSLALMLAVPFAPQAVAKTAAATTASQPEIASGSAM
                     IVDLNTNKVIYSNHPDLVRPIASISKLMTAMVVLDARLPLDEKLKVDISQTPEMKGVY
                     SRVRLNSEISRKDMLLLALMSSENRAAASLAHHYPGGYKAFIKAMNAKAKSLGMNNTR
                     FVEPTGLSVHNVSTARDLTKLLIASKQYPLIGQLSTTREDMATFSNPTYTLPFRNTNH
                     LVYRDNWNIQLTKTGFTNAAGHCLVMRTVINNKPVALVVMDAFGKYTHFADASRLRTW
                     IETGKVMPVPAAALSYKKQKAAQMAAAGQTAQND"
     gene            complement(5257..6972)
                     /gene="dld"
                     /locus_tag="RN951_003041"
     CDS             complement(5257..6972)
                     /gene="dld"
                     /locus_tag="RN951_003041"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HDX2528012.1"
                     /translation="MSSMTTTDNKAFLNELARLVGHSHLLTDPAKTARYRKGFRSGQG
                     DALAVVFPGSLLELWRVLKACVTADKIILMQAANTGLTEGSTPNGNDYDRDIVIISTL
                     RLDKLHVLGKGEQVLAYPGTTLYSLEKALKPLGREPHSVIGSSCIGASVIGGICNNSG
                     GSLVQRGPAYTEMSLFARINEDGKLTLVNHLGIDLGETPEQILSKLDDDRIKDDDVRH
                     DGRHAHDYDYVHRVRDIEADTPARYNADPDRLFESSGCAGKLAVFAVRLDTFEAEKNQ
                     QVFYIGTNQPEVLTEIRRHILANFENLPVAGEYMHRDIYDIAEKYGKDTFLMIDKLGT
                     DKMPFFFNLKGRTDAMLEKVKFFRPHFTDRAMQKFGHLFPSHLPPRMKNWRDKYEHHL
                     LLKMAGDGVGEAKSWLVDYFKQAEGDFFVCTPEEGSKAFLHRFAAAGAAIRYQAVHSD
                     EVEDILALDIALRRNDTEWYEHLPPEIDSQLVHKLYYGHFMCYVFHQDYIVKKGVDVH
                     ALKEQMLELLQQRGAQYPAEHNVGHLYKAPETLQKFYRENDPTNSMNPGIGKTSKRKN
                     WQEVE"
     gene            7168..9465
                     /gene="bglX"
                     /locus_tag="RN951_003042"
     CDS             7168..9465
                     /gene="bglX"
                     /locus_tag="RN951_003042"
                     /EC_number="3.2.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucosidase BglX"
                     /protein_id="HDX2528013.1"
                     /translation="MKWLCSVGIAVSLALQPALADDLFGNHPLTPEARDAFVTELLKK
                     MTVDEKIGQLRLISVGPDNPKEAIREMIKDGQVGAIFNTVTRQDIRAMQDQVMELSRL
                     KIPLFFAYDVLHGQRTVFPISLGLASSFNLDAVKTVGRVSAYEAADDGLNMTWAPMVD
                     VSRDPRWGRASEGFGEDTYLTSTMGKTMVEAMQGKSPADRYSVMTSVKHFAAYGAVEG
                     GKEYNTVDMSPQRLFNDYMPPYKAGLDAGSGAVMVALNSLNGTPATSDSWLLKDVLRD
                     QWGFKGITVSDHGAIKELIKHGTAADPEDAVRVALKSGINMSMSDEYYSKYLPGLIKS
                     GKVTMEELDDAARHVLNVKYDMGLFNDPYSHLGPKESDPVDTNAESRLHRKEAREVAR
                     ESLVLLKNRLETLPLKKSATIAVVGPLADSKRDVMGSWSAAGVADQSVTVLTGIKNSV
                     GENGKVLYAKGANVTSDKGIIDFLNQYEEAVKVDPRSPQEMIDEAVQTAKQSDVVVAV
                     VGEAQGMAHEASSRTDITIPQSQRDLIAALKATGKPLVLVLMNGRPLALVKEDQQADA
                     ILETWFAGTEGGNAIADVLFGDYNPSGKLPMSFPRSVGQIPVYYSHLNTGRPYNADKP
                     NKYTSRYFDEANGALYPFGYGLSYTTFTVSDVKLSAPTMKRDGKVTASVQVTNTGKRE
                     GATVVQMYLQDVTASMSRPVKQLKGFEKITLKPGETQTVSFPIDIEALKFWNQQMKYD
                     AEPGKFNVFIGTDSARVKKGEFELL"
     gene            9676..10593
                     /gene="osmF"
                     /locus_tag="RN951_003043"
     CDS             9676..10593
                     /gene="osmF"
                     /locus_tag="RN951_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein OsmF"
                     /protein_id="HDX2528014.1"
                     /translation="MPLLKLWAGSLVMLAAVSLPLQAASPVKVGSKIDTEGALLGNII
                     LQVLESHGVPTVNKVQLGTTPVVRGAITSGELDIYPEYTGNGAFFFKDENDAAWKNAQ
                     QGYEKVKKLDSEHNKLIWLTPAPANNTWTIAVRQDVAEKNKLTSLADLSRYLQEGGTF
                     KLAASAEFIERADALPAFEKAYGFKLGQDQLLSLAGGDTAVTIKAAAQQTSGVNAAMA
                     YGTDGPVAALGLQTLSDPQGVQPIYAPAPVVRESVLKEYPQMAQWLQPVFASLDAKTL
                     QQLNASIAVEGLDAKKVAADYLKQKGWTK"
     gene            10600..11757
                     /gene="yehY"
                     /locus_tag="RN951_003044"
     CDS             10600..11757
                     /gene="yehY"
                     /locus_tag="RN951_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter permease YehY"
                     /protein_id="HDX2528015.1"
                     /translation="MTYLRINPVLALLLLLTAIAAALPFISYAPNRLVSGEGRHLWQL
                     WPQTIWMLVGFGCAWLTACFIPAKKGSIFALILAQFVFVLLVWGAGKAATQLAQNGSA
                     LARTSLGSGFWLAAALALLACSDAIRRISTHPLWRWLLHMQIAIIPLWLLYSGTLNDL
                     SLMKEYANRQDVFDDALAQHLTLLFGAVLPALVIGVPLGIWCYFSTARQGAIFSLLNV
                     IQTVPSVALFGLLIAPLAALVTAFPWLGKLGIAGTGMTPALIALVLYALLPLVRGVVV
                     GLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALIG
                     AGGFGALVFQGLLSSAIDLVLLGVIPVIVLAVLIDALFDLLIALLKVKRND"
     gene            11750..12676
                     /gene="yehX"
                     /locus_tag="RN951_003045"
     CDS             11750..12676
                     /gene="yehX"
                     /locus_tag="RN951_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter ATP binding
                     protein YehX"
                     /protein_id="HDX2528016.1"
                     /translation="MIEFSHVSKLFGAQKAVNDLNLNFQEGSFSVLIGTSGSGKSTTL
                     KMINRLVEHDSGEIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHWSVAQNIATVPQL
                     QKWSRARIDDRIDELMTLLGLESNLRERYPHQLSGGQQQRVGVARALAADPQVLLMDE
                     PFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDHGEVVQQGN
                     PLTMLTRPANDFVRQFFGRSELGVRLLSLRSVADYVRREERAEGEALAEEMTLRDALS
                     LFVARGCEVLPVMNTQGQPCGTLHFQDLLEEA"
     gene            12681..13412
                     /gene="yehW"
                     /locus_tag="RN951_003046"
     CDS             12681..13412
                     /gene="yehW"
                     /locus_tag="RN951_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter permease YehW"
                     /protein_id="HDX2528017.1"
                     /translation="MKMLRDPLFWLIALFVALIFWLPYSQPLFAALFPQLPRPVYQQE
                     SFAALALAHFWLVGISSLFAVIIGTGAGIAVTRPWGAEFRPLVETIAAVGQTFPPVAV
                     LAIAVPVIGFGLQPAIIALILYGVLPVLQATLAGLGAIDASVTEVAKGMGMSRGQRLR
                     KVELPLAAPVILAGVRTSVIINIGTATIASTVGASTLGTPIIIGLSGFNTAYVIQGAL
                     LVALAAIIADRLFERLVQALSQHAK"
     gene            complement(13393..13500)
                     /locus_tag="RN951_003047"
     CDS             complement(13393..13500)
                     /locus_tag="RN951_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YohO"
                     /protein_id="HDX2528018.1"
                     /translation="MRIAKIGVIALFLFMALGGIGGVMLAGYTFILRAG"
     gene            complement(13560..14291)
                     /gene="mlrA"
                     /locus_tag="RN951_003048"
     CDS             complement(13560..14291)
                     /gene="mlrA"
                     /locus_tag="RN951_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MlrA"
                     /protein_id="HDX2528019.1"
                     /translation="MALYTIGEVALLCDINPVTLRAWQRRYGLLKPQRTDGGHRLFND
                     ADIDRIREIKRWIDNGVQVSKVKMLLSNENVDVQNGWRDQQETLLTYLQSGNLHSLRT
                     WIKERGQDYPAQTLTTHLFIPLRRRLQCQQPTLQALLAILDGVLINYIAICLASARKK
                     QGKDALVVGWNIQDTTRLWLEGWIASQQGWRIDVLAHSLNQLRPELFEGRTLLVWCGE
                     NRTSAQQQQLTSWQEQGHDIFPLGI"
     gene            14513..16198
                     /gene="btsS"
                     /locus_tag="RN951_003049"
     CDS             14513..16198
                     /gene="btsS"
                     /locus_tag="RN951_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component regulatory system sensor histidine
                     kinase BtsS"
                     /protein_id="HDX2528020.1"
                     /translation="MYDFNLVLLLLQQMCVFLVIAWLMSKTPLFIPLMQVTVRLPHKF
                     LCYIVFSIFCIMGTWFGLHIDDSIANTRAIGAVMGGLLGGPVVGGLVGLTGGLHRYSM
                     GGMTALSCMISTIVEGLLGGLVHSILIRRGRTDKVFNPITAGAVTFVAEMVQMLIILA
                     IARPYEDAVRLVSNIAAPMMVTNTVGAALFMRILLDKRAMFEKYTSAFSATALKVAAS
                     TEGILRQGFNEVNSMKVAQVLYQELDIGAVAITDREKLLAFTGIGDDHHLPGKPISST
                     YTLKAIETGEVVYADGNEVPYRCSLHPQCKLGSTLVIPLRGENQRVMGTIKLYEAKNR
                     LFSSINRTLGEGIAQLLSAQILAGQYERQKAMLTQSEIKLLHAQVNPHFLFNALNTIK
                     AVIRRDSEQASQLVQYLSTFFRKNLKRPSEFVTLADEIEHVNAYLQIEKARFQSRLQV
                     NIAIPQELSQQQLPAFTLQPIVENAIKHGTSQLLDTGRVAISARREGQHLMLEIEDNA
                     GLYQPVTNASGLGMNLVDKRLRERFGDDYGISVACEPDSYTRITLRLPWRDEA"
     gene            16195..16914
                     /gene="yehT"
                     /locus_tag="RN951_003050"
     CDS             16195..16914
                     /gene="yehT"
                     /locus_tag="RN951_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310963.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BtsR"
                     /protein_id="HDX2528021.1"
                     /translation="MIKVLIVDDEPLARENLRVFLQEQSDIEIVGECSNAVEGIGAVH
                     KLRPDVLFLDIQMPRISGLEMVGMLDPEHRPYIVFLTAFDEYAIKAFEEHAFDYLLKP
                     IDEARLEKTLARLRQERSKQDVSLLPENQQALKFIPCTGHSRIYLLQMKDVAFVSSRM
                     SGVYVTSHEGKEGFTELTLRTLESRTPLLRCHRQYLVNLAHLQEIRLEDNGQAELILR
                     NGLTVPVSRRYLKSLKEAIGL"
     gene            16961..17431
                     /locus_tag="RN951_003051"
     CDS             16961..17431
                     /locus_tag="RN951_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HDX2528022.1"
                     /translation="MLSNDILRSVRYILKANNNDLVRILALGNVEATAEQIAVWLRKE
                     DEEGFQRCPDIVLSSFLNGLIYEKRGKDESAPALEPERRINNNIVLKKLRIAFSLKTD
                     DILAILTEQQFRVSMPEITAMMRAPDHKNFRECGDQFLRYFLRGLAARQHVKKG"
     gene            complement(17471..17932)
                     /locus_tag="RN951_003052"
     CDS             complement(17471..17932)
                     /locus_tag="RN951_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416627.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YehR family lipoprotein"
                     /protein_id="HDX2528023.1"
                     /translation="MKAFNKLFSLVVASVLVFSLAGCGDKEESKKFSANLNGTEIAIT
                     YVYKGDKVLKQSSETKIQFASIGATTKEDAAKTLEPLSAKYKNIAGVEEKLTYTDTYA
                     QENVTIDMEKVDFKALQGISGINVSAEDAKKGITMAQMELVMKAAGFKEVK"
     gene            complement(18057..20057)
                     /locus_tag="RN951_003053"
     CDS             complement(18057..20057)
                     /locus_tag="RN951_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HDX2528024.1"
                     /translation="MNSLRPELLELTPQALTALSNAGFVKRSLKELENGNVPEISHEN
                     SALIATFSDGVRTQLANGQALKEAQCSCGASGMCRHRVMLVLSYQRLCTTAQPTEKEE
                     AWDPAIWLEELATLPDATRKRAQALVAKGITIELFCAPGEIPSARLPMSDVRFYSRSS
                     IRFARCDCIEGTLCEHVVLAVQAFVEAKAQQAEFNHLIWQMRSEHVTSSDDPFASEEG
                     QTCRQYVQQLSQALWLGGISQPLIHYEAAFNRALQAAEACNWRWVSESLRQLRASVDA
                     FHTRASHYHAGECLRQLAALNSRLNCAQEMARRDSVGEVPPVPWRTVVGSGIAGEAKL
                     DHLRLVSLGMRCWQDIEHYGLRIWFTDPDTGSILHLSRSWPRSEQENSPAAMRRLFSF
                     QAGALAGGQIVSQAAKRSADGELLLATRNRLSSVVPLSPDAWQMLSAPLRQPGIVALR
                     EYLRQRPPACIRPLNQVDNLFILPVAECISLGWDSSRQTLDAQVISGEGEDNLLTLSL
                     PASACSPFAVERMAALLQQTDDPVSLVSGFVSFVDGQLTLEPRVMMTKTRAWALDAET
                     APVAPLPSASVLPVPSTAHQLLMRCQALLIQLLHNGWRYQEQSAISQAELLANDLSAV
                     GFYRLAHMLGQFRNTESEARVEAMNNGVLLCEQLFPMLQQQG"
     gene            complement(20054..21190)
                     /locus_tag="RN951_003054"
     CDS             complement(20054..21190)
                     /locus_tag="RN951_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDX2528025.1"
                     /translation="MSKLNDLLTTRELQRWRLILGEAAETTLCGLDDNARQIDHALEW
                     LYGRDPERLQRGERSGGLGGSNLTTPEWINSIHTLFPQQVIERLESDAVLRYGIEDVV
                     TNLDVLERMQPSESLLRAVLHTKHLMNPEVLAAARQIVRQVVEEIMARLAKEVRQAFS
                     GVRDRRRRSFIPLARNFVFKSTLRANLQHWHPQHGKLYIESPRFNSRIKRQSEQWQLV
                     LLVDQSGSMVDSVIHSAVMAACLWQLPGIRTHLVAFDTSVVDLTADVADPVELLMKVQ
                     LGGGTNIASAVEYGRQLIEQPAKSVIILVSDFYEGGSSSLLTHQVKKCVQSGIKVLGL
                     AALDSTATPCYDHDTAQALVNVGAQIAAMTPGELASWLAENLQS"
     gene            complement(21183..23462)
                     /locus_tag="RN951_003055"
     CDS             complement(21183..23462)
                     /locus_tag="RN951_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708008.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528026.1"
                     /translation="MSEPLIVGIRHHSPACARLVKSLIESQRPRYVLIEGPADFNDRV
                     DELFLAHQLPVAIYSYCQYQDGAAPGRGAWTPFAEFSPEWQALQAARRIQAQTYFIDL
                     PCWAQSEEVDDSPDTQEESQALLLRATRMDNSDTLWDHLFEDESQQTALPSALAHYFA
                     QLRGDSPGDALNRLREAFMARWIGWAMQQNNGDVLVVCGGWHAPVLAKMWRECPQEIN
                     TPELPSLADAVTGCYLTPYSEKRLDVLAGYLSGMPAPVWQNWCWQWGLQQAGEQLLKT
                     VLTRLRQHKLPASTADMAAAHLHAMALAQLRGHTLPLRTDWLDAIAGSLIKEALNAPL
                     PWSYRGVIHPDTDPILLTLIDTLAGDGFGKLAPSTPQPPLPKDVTCELERTAISLPAE
                     LTLNRFNPNGLAQSQVLHRLAILEIPGIVRQQGSTLTLAGNGEEHWKLTRPLSQHAAL
                     IEAACFGATLQEAARHKLEADMLDAGGIGSITTCLSQAALAGLASFSQQLLEQLTLLI
                     AQENQFAEMGQALEVLYALWRLDEISGMQGAQILQTTLCAAIDRTLWLCESNGRPDEK
                     EFHAHLHSWQALCHILRDLHSGVNLSGVSLSAAVALLERRSQAIHAPALDRGAVLGAL
                     MRLEHPNASAEAALTMLAQLSPAQSGEALQGLLALARHQLACQPTFIAGFSSHLNQLS
                     DADFINALPDLRAAMAWLPPRERGTLAHQVLEHYQLAQLPVSALQMPLHCPPQAIAHH
                     QQLEQQALASLQHWGVFHV"
     gene            complement(23473..24561)
                     /locus_tag="RN951_003056"
     CDS             complement(23473..24561)
                     /locus_tag="RN951_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310954.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDX2528027.1"
                     /translation="MSPQNNHLQRPPAAVLYADELAKLKQNDNAPCPPGWQLSLPAAR
                     AFILGDSAQNISRKVVISPSAVERMLVTLATGRGLMLVGEPGTAKSLLSELLATAISG
                     DAGLTIQGGASTTEDQIKYGWNYALLINHGPSTEALVPAPLYQGMRDGKIVRFEEITR
                     TPLEVQDCLLGMLSDRVMTVPELTGEASQLYAREGFNIIATANTRDRGVNEMSAALKR
                     RFDFETVFPIMDFAQELELVASASARLLAHSGIPHKVPDAVLELLVRTFRDLRANGEK
                     KTSMDTLTAIMSTAEAVNVAHAVGVRAWFLANRAGEPADLVDCIAGTIVKDNEEDRAR
                     LRRYFEQRVATHKEAHWQAYYQARHRLP"
BASE COUNT         5884 a         6385 c         6833 g         5997 t
ORIGIN      
        1 ttatatgaag caatgcacat gacaggagcg caacaggatg agagactgaa atattctcgt
       61 tattttcgga cctgatgaca ttaattaatt ttaaaatatc atcttaaata cgccagtcac
      121 caccagtagc ccaatcagga aaataaacaa tacagcccag agtataattt tcattggcgt
      181 tcctttattt gtgagtgctg aataagtata ggaaaaaacg aagccctttg ccgttatcca
      241 taaacgatta agataaatcg gaagatatca ttcacttagt gtatattttt ctggatatgt
      301 cgttttattg ctactgatgt attgccacgc gaaactaaaa aatatatcgc aacacacggt
      361 aatctccgcg caccttttct tacctgatta ttcccccatg aatcgtgatt ccttttatcc
      421 cgccatcgcc tgttttccgc tgttactgat gctggccggg tgtgcaccta tgcatgaaac
      481 ccgccaggcg ttaagccagc aaacgcctgc tgcacaagtt gacaccgcat tacccacggc
      541 gctgaaaaat ggttggccag acagccaatg gtggctggag tatcacgata atcaactcac
      601 ttccttaatt aacaatgcac tacagaacgc accggatatg caggtggctg aacagcgcat
      661 tcagctagct gaagcccagg cgaaggcaat tgctactcag gatggtccgc agatcgactt
      721 ttctgcggat atggagcggc aaaaaatgtc ggcagaaggc ttaatggggc cgtttgctct
      781 gaacgatccg gccgcaggta cgaccggtcc gtggtacacc aacggaactt ttggcttaac
      841 ggcgggctgg catctcgata tctggggaaa gaatcgggcg gaggttactg cccgcctggg
      901 tacggttaaa gcacgggcgg cggaacgcga gcaaacccgc caattgctgg ctggcagcgt
      961 agcccgcctg tactgggagt ggcaaaccca ggcggcgtta aacacggtct tgcagcaaat
     1021 agaaaaagag cagaacacca ttatcgcgac cgatcgccag ctatatcaga acgggattac
     1081 ttcttcagtt gaaggtgtgg aaaccgatat taatgccagc aaaacccggc agcagctcaa
     1141 cgatgtcgcg gggaaaatga aaattattga ggcacggtta agcgcactta caaataacca
     1201 gacaaagtca ttgaagctta aaccggtcgc gttgccgaaa gtggcaagcc agcttcctga
     1261 tgaactgggg tactccttac tggcccggcg ggcagatttg caggcggcgc actggtacgt
     1321 tgagtcatcg ctaagcacca ttgatgcggc aaaagcggca ttttatcctg acatcaacct
     1381 gatggccttc ctgcaacagg atgcgttgca cttaagcgat ctgttccgtc attccgcgca
     1441 gcaaatgggc gttacggcag gcctgacgct acccattttc gatagtggtc gtcttaacgc
     1501 caatctcgat atcgcaaaag ccgaaagcaa cttgtctatc gccagctaca acaaagcggt
     1561 ggttgaagcg gtgaatgacg tggcgcgggc agccagtcag gttcagacac ttgcggagaa
     1621 aaaccagcat caggcgcaaa ttgagcgcga tgccttgcgt gtggtaggtc ttgcgcaggc
     1681 gcgctttaac gcgggcatca ttgctggttc ccgcgtcagc gaagccagaa tccccgcgct
     1741 gcgtgagcgg gccaatggcc tgttattgca agggcagtgg ctggatgctt ccattcaact
     1801 cactggtgcg ttgggcgggg gttacaaacg ctgatgatat gcgccttcta tacttaacgt
     1861 ttattcagcg ttaagtggag aactcgatgg cacaggttgc gattattacc gcctccgatt
     1921 cggggatcgg caaagagtgc gcgttattac tggcgcagca ggggtttgat attggcatta
     1981 cctggcactc agatgaagaa ggggcaaaag ataccgcgcg tgaggtagtt agccacggcg
     2041 tacgtgcgga gatcgtgcag ctggatctcg gtaaactgcc agaaggtgcg caggcgctgg
     2101 agaaactcat tcaacggctg gggcgtattg atgtgctggt gaataatgcg ggcgcaatga
     2161 ccaaagcgcc gtttcttgat atggctttcg atgagtggcg caagattttt accgttgatg
     2221 tcgatggtgc atttttatgc tcacaaattg cggcccgcca gatggtgaaa caagggcagg
     2281 gcggtcgcat catcaacatt acgtcggtac atgaacatac gccgctgccg gatgccagcg
     2341 cttacacagc cgctaaacat gcgctcggcg ggttaaccaa aacgatggcg ctggagctgg
     2401 tcaggcataa gattttggtg aacgcagtcg cgcctggggc gatcgccacg ccaatgaatg
     2461 gcatggatga cagcgacgtg aagcccgacg cggagccttc gattcctctg cggcgttttg
     2521 gcgcaacgca tgagattgcc agcctggtag cgtggctgtg ctcagagggc gcaaattaca
     2581 ccaccgggca gtcgttgata gtggatggcg gctttatgtt ggcgaatccg cagttcaacc
     2641 cagaatagcg cagtgaggtg cgtggttatt tcaatgggta aaattttggt aggcatgata
     2701 agacgcacaa gcgtcgcatc aggcatggtg caccggatgt cggatgcggc gcgaacgcct
     2761 tacccagggc aatggtttta cgcctgatga tccggctttt tcttcccgcg ccgtttcagc
     2821 caccagcgca cgcccaccac cagaaccacg accagaatca accagaccca gtgcttcaaa
     2881 tgctggtcga gattgtgcaa ccacggcgca atcacctgac caccagcgta accaatagtg
     2941 gtaaaaatca acgcccaggc aaatgcgccg agaatattca gcggcagaaa gattttcggc
     3001 ggcagctggc tggcaccaat cagcgtcggg ccaatcaccc gaaagccata cataaagcgc
     3061 gtaccaatga caaacagata cggatggcgt tggataagtt tctgcgcccg ctcaatttta
     3121 tcctgatgtt tcgagaaacg gcgtaacagc ttgccgccaa accgccgccc gcacagatag
     3181 agcacctggt cgccaatcat gccgccaagc gccacagaaa gtaccaccag cgggaacttt
     3241 aatagcccct gatgcgccgc aacgcctccc agcaaagtca cggtttcacc ttccgccagg
     3301 ctaccgatca ccagcgcggc ataaccatat tgtgagataa gtgtattgag atccataggc
     3361 cagtctgtct ccctttggtt gccagtaagc atacaccctg tgaatcattc acgctgaaaa
     3421 aggacgttca tcagacagtg aaaattacat gggcgaacaa aaaataatca caagctgact
     3481 tatacttgaa ctgtcaggtt catgaactca caacaagggg gcggtatgag ccatgtctgg
     3541 ggactgtttt cccatcccga tcgtgaaatg caggtgatta atcgcgaaaa cgaaacgatt
     3601 tctcaccatt acacccacca cgttttgctg atggcggcga ttccggtgat ttgcgccttc
     3661 attggcacta cacagattgg ctggaatttt ggcgatggca ctatcctgaa gttatcctgg
     3721 tttaccggac tggcgctggc tgtcttgttt tacggcgtta tgctggctgg ggtcgcggtg
     3781 atggggcggg tcatctggtg gatggcgcgt aattatccgc agcgtccgtc acttgcgcac
     3841 tgcatggtct tcgcgggcta cgttgcaact ccgctgtttt taagcggtct ggtggcgctt
     3901 tatccactgg tctggttgtg tgcgctggtc ggcacggtgg cgctgtttta caccggctac
     3961 ctgctttacc ttggtattcc gagcttcctg aatatcaaca aagaggaagg ccttagcttc
     4021 tctagttcga cgctggcgat tggcgtgctg gtactggaag tgctgctcgc cctaaccgtt
     4081 atactatggg gctacggtta tcgtttgttc tagaaagttc tttgacgttg cattgctggc
     4141 gtaaatgtca gcaatgcagc atttcctcac gattctcctt tgacgatcgc actttttgct
     4201 cgttatgatg gcgtcgctag cctcagtaaa tccttactcc ggcggtgcgc aacccgtgcg
     4261 cgtgaaccac tatctgaatg ctcatcatgc cgaaatttcg agtttcttta tttagcctgg
     4321 ccctgatgct ggctgtgcct tttgcaccgc aggccgttgc gaaaacggca gccgctacca
     4381 ccgcttcaca accggaaatt gcctccggta gcgcgatgat tgttgatctg aataccaaca
     4441 aagtgatcta ttcgaaccac ccggatctgg tgcgtccgat tgcgtctatc agcaaattaa
     4501 tgaccgcgat ggttgtgctg gatgcacgac tgccgctgga tgaaaaacta aaagtggata
     4561 tcagccagac gccggagatg aaaggggtct attcgcgcgt acgactgaat agcgaaatca
     4621 gccgtaaaga tatgctgttg ctggcgctga tgtcttcaga aaaccgcgcg gcggcaagcc
     4681 ttgcacacca ttatcccggt ggttacaaag cctttattaa ggcaatgaat gcgaaagcga
     4741 aatcgctcgg aatgaacaac acgcgctttg ttgaacctac cggattgtcg gtgcataacg
     4801 tttcaactgc ccgtgactta accaaactgc tcattgccag caaacaatat ccgttgatcg
     4861 ggcagttaag tactacccgg gaagatatgg caaccttctc taacccgacg tatacgctgc
     4921 cgttccgcaa tactaatcat ctggtgtatc gcgataactg gaatattcag ttaaccaaaa
     4981 ccggctttac caatgcggcg ggccattgtc tggtgatgcg tacggttatc aataataaac
     5041 cggtggcgct ggtagtgatg gacgcgtttg gcaaatatac ccattttgcc gatgccagcc
     5101 gcctgcgtac ctggattgaa accggtaaag tgatgcctgt gccggcagca gcgttgagct
     5161 ataaaaaaca aaaagccgcc caaatggcgg cggcggggca gacggcacag aacgattaag
     5221 tgaattcgga tggcgatact ctgccatccg taatttttac tccacttcct gccagttttt
     5281 ccgtttactg gttttaccga tccccggatt catgctgttg gtcggatcgt tctcgcgata
     5341 gaacttctgc aacgtctccg gtgctttata caaatgaccg acgttatgct cggcagggta
     5401 ttgcgcgccg cgctgctgta gcagttccag catctgttct tttaacgcat gcacatccac
     5461 gccttttttc actatgtaat cctgatggaa gacatagcac ataaaatggc cgtaatagag
     5521 cttgtgcacc agctggctgt cgatctccgg cggtaaatgc tcataccact cggtgtcgtt
     5581 acgccgcaga gcgatatcca acgccagaat gtcttcgact tcatcggaat gcaccgcctg
     5641 ataacgaatt gctgcgcccg cagcggcgaa acggtgtaaa aacgctttgc tgccttcctc
     5701 cggcgtacag acaaagaaat cgccttcggc ctgtttgaaa taatccacca accacgattt
     5761 ggcttcgccc acgccatcgc ccgccatttt taacagcaga tgatgctcgt atttatcgcg
     5821 ccagtttttc atgcgcggcg gtaaatggct ggggaacagg tgaccgaatt tttgcatcgc
     5881 acggtcagta aaatgcggac ggaagaattt cactttctcc agcatcgcat cggtgcgtcc
     5941 cttgagatta aagaagaacg gcatcttgtc ggtgcctaac ttatcaatca tcaggaaggt
     6001 gtctttgccg tatttttccg caatatcgta gatatcccgg tgcatatatt ccccggcaac
     6061 cggcagattt tcgaagttag ccagaatatg acggcggatt tcggtcagca cttccggctg
     6121 gttggtgccg atataaaaca cctgctgatt tttttccgct tcgaaggtat ctagacgtac
     6181 cgcaaagacg gccagcttcc cggcgcaacc agaagattca aataaccgat ccggatcggc
     6241 gttataacgt gcgggcgtgt cggcttcaat atcacgaacg cggtggacat agtcataatc
     6301 gtgggcgtga cgaccatcgt gacgcacatc gtcatctttg atgcgatcat catccagctt
     6361 gctaaggatc tgctccggcg tttcgcccag atcaatcccc agatggttca ccagcgtcag
     6421 tttgccgtct tcatttatac gcgcgaataa cgacatttcg gtatacgccg ggccacgttg
     6481 caccagcgag ccgccggagt tgttacaaat accgccgata accgatgcgc ctatacacga
     6541 cgatccaatc accgagtgcg gttcgcgtcc cagcggtttg agggcttttt ccagcgaata
     6601 gagcgtggtg cccggatagg ccagcacctg ttcgcccttg ccaagaacgt gcagcttgtc
     6661 gagacgcagg gtgctgatga tcacgatatc gcgatcatag tcgttaccgt ttggcgtcga
     6721 tccttcggtc aggcctgtat tggcagcctg catcagaata attttgtcgg cggtgacaca
     6781 ggctttcagc acccgccaca attccagtag tgagccaggg aaaacgacag ctagcgcgtc
     6841 gccctgacca gaacggaagc ccttgcgata gcgggccgtt tttgcgggat cggtgagcag
     6901 gtgtgaatga ccgaccagac gggcaagttc attcaaaaag gctttattat cagttgttgt
     6961 catggaagac attttccact ccttgtggtg gcgaaaaaat atcacaaact agaatagcgc
     7021 cttgtatgac aattcagcga gtgaatattt tgaaaattca gacaataaac tgagcattct
     7081 ttttctctct ccatcatgct tatggcaaac tacggttttt gcaccatttt cgctgcctcg
     7141 tcgggcaaca gaggaagaaa aatccatatg aaatggctat gttcagtagg aatcgcggtg
     7201 agtctggccc tgcagccagc actggcggat gatttattcg gcaaccatcc attaacgccc
     7261 gaagcgcggg atgcgttcgt caccgaactg cttaagaaaa tgacagttga tgagaaaatt
     7321 ggtcagctgc gcttaatcag cgtcggcccg gataacccga aagaggcgat ccgcgagatg
     7381 atcaaagacg gtcaggttgg ggcgattttc aacaccgtaa cccgtcagga tatccgcgcc
     7441 atgcaggatc aggtgatgga attaagccgc ctgaaaattc ctcttttctt tgcttacgac
     7501 gtgctgcacg gtcagcgcac ggtgttcccg attagcctcg gtctggcctc gtcttttaac
     7561 ctcgatgcag tgaaaacggt cggacgtgtc tctgcttatg aagcggcaga tgatggcctg
     7621 aatatgacct gggcaccgat ggtcgatgtc tcgcgcgatc cgcgctgggg acgtgcttcc
     7681 gaaggttttg gcgaagatac gtatctcacc tcaacaatgg gtaaaaccat ggtggaagcg
     7741 atgcagggta aaagcccggc agatcgctac tcggtgatga ccagcgtcaa acactttgcc
     7801 gcatacggcg cggtagaagg cggtaaagag tacaacaccg tcgatatgag tccgcagcgc
     7861 ctgtttaatg attatatgcc gccgtacaaa gcggggctgg acgcaggcag cggcgcggtg
     7921 atggtggcgc tgaactcgct gaacggcacg ccagccacct ccgattcctg gctgctgaaa
     7981 gatgttctgc gcgaccagtg gggctttaaa ggcatcaccg tttccgatca cggtgcaatc
     8041 aaagagctga ttaaacatgg cacggcggca gacccggaag atgcggtgcg cgtggcgctg
     8101 aaatccggaa tcaacatgag tatgagcgac gagtattact cgaagtatct gcctgggttg
     8161 atcaaatccg gcaaagtgac gatggaagag ctggacgatg ctgcccgcca tgtactgaac
     8221 gttaaatatg atatgggatt gtttaacgac ccatacagcc atttggggcc gaaagagtct
     8281 gacccggtgg ataccaatgc cgaaagccgc ctgcaccgta aagaagcgcg tgaagtggcg
     8341 cgcgaaagcc tggtgttgct gaaaaaccgt ctcgaaacgt taccgctgaa aaaatcggcc
     8401 accattgcgg tggttgggcc actggcggac agtaaacgtg acgtgatggg cagctggtcc
     8461 gcagccggtg ttgccgatca atccgtgacc gtactgaccg ggattaaaaa ttccgtcggt
     8521 gaaaacggta aagtgctgta tgccaaaggg gcgaacgtta ccagtgacaa aggcattatc
     8581 gatttcctga atcagtatga agaagcggtc aaagtcgatc cgcgttcgcc gcaagagatg
     8641 attgatgaag cggtgcagac ggcgaaacaa tctgatgtgg tggtggctgt agtcggtgaa
     8701 gcacagggga tggcgcacga agcctccagc cggaccgata tcactattcc gcaaagccaa
     8761 cgtgacttga ttgcggcgct gaaagccacc ggtaaaccgc tggtgctggt actgatgaac
     8821 gggcgtccgc tggcgctggt gaaagaagat cagcaggctg atgcgattct ggaaacctgg
     8881 tttgcgggga ctgaaggcgg taatgcaatt gccgatgtat tgtttggcga ttacaacccg
     8941 tccggcaagc tgccaatgtc cttcccgcgt tctgtcgggc agatcccggt gtactacagc
     9001 catctgaata ccggtcgccc gtataatgcc gacaagccga acaaatacac ttcgcgttat
     9061 tttgatgaag ctaacggggc gttgtatccg ttcggctatg ggctgagcta caccactttc
     9121 accgtctctg atgtgaaact ttctgcgccg accatgaagc gtgacggcaa agtgactgcc
     9181 agcgtgcagg tgacgaacac cggtaagcgc gagggggcca cggtagtgca gatgtacttg
     9241 caggatgtga cggcttccat gagtcgccct gtgaaacagc tgaaaggctt tgagaaaatc
     9301 accctgaaac cgggcgaaac tcagactgtc agcttcccga tcgatattga ggcgctgaag
     9361 ttctggaatc aacagatgaa atatgacgcc gagcctggca agttcaatgt ctttatcggc
     9421 actgattccg cacgcgttaa gaaaggcgag tttgagttgc tgtaatgctt tagtaagggc
     9481 gcgacgtttg cgccctttgt aggccggata aggcgctcgc gccgcatccg gcaggaaacg
     9541 ccggaccgaa tatgcctctt aagtatttat ctgattctgc aactgaatcc ttccgctcaa
     9601 gctaaccccg ccattatcaa ctatgctttt ctcttaattc gctgaaaaca acagtaaaag
     9661 aatgaggaaa gcatcatgcc actcttaaag ctctgggcag gttcactggt tatgttggca
     9721 gccgtgagcc tgccgctaca ggcggcttcc cccgttaaag tcggttcaaa aatcgatacc
     9781 gaaggtgcgc tactcggcaa tatcattttg caggtgctgg aaagccacgg cgtaccgacg
     9841 gtgaataaag tgcaactcgg aacgactcct gtggtgcgcg gggcgattac ttccggtgaa
     9901 ctggatatct atccggaata taccggcaat ggcgctttct tctttaaaga tgaaaacgat
     9961 gcagcgtgga aaaacgcgca gcaaggttac gagaaagtca aaaagctcga ttcggagcac
    10021 aacaagttaa tctggctgac gcccgcgcct gcaaataaca cctggactat cgccgtgcgt
    10081 caggatgtgg cagagaaaaa taaactcact tcgcttgccg acctgagtcg ttatctgcaa
    10141 gagggcggca ccttcaaact ggcagcctcg gcagagttta tcgaacgcgc cgatgcgtta
    10201 cccgcgtttg aaaaagccta tggctttaag ctcggtcagg atcagttgct gtcactggct
    10261 ggtggcgaca cggcggtgac gatcaaagcc gctgcccagc aaacctctgg cgttaatgct
    10321 gcaatggctt acggcactga cggcccggta gcggcgctgg ggctgcaaac cttaagcgat
    10381 ccgcaaggcg tgcaacctat ctacgcgcct gcaccagtgg tgcgtgagtc ggtgctgaaa
    10441 gagtatccgc aaatggcaca gtggctacag ccagtcttcg ccagcctcga tgcaaaaaca
    10501 ttgcagcaac tgaatgccag cattgcagtg gaaggactgg atgccaaaaa agtggctgcc
    10561 gactacctga aacaaaaagg gtggacgaag taatttcccg tgacttatct acgtattaat
    10621 cctgttctgg cgctgctgct gttgctgacg gcaatcgcag cagcgctgcc gtttatcagc
    10681 tacgcgccta atcgtttagt ctcgggtgaa gggcgacatc tctggcagct gtggccgcaa
    10741 acgatctgga tgctggtggg ctttggttgc gcctggctga cagcctgttt tattcccgct
    10801 aaaaaaggca gcatttttgc actcattctg gcgcaattcg tcttcgtatt gctggtgtgg
    10861 ggagctggaa aagcggcgac ccaactggcg caaaatggca gtgcgctggc gcgtaccagc
    10921 ctcggcagtg gtttctggct ggctgcggcg ctggcattgc tggcctgtag cgatgccatc
    10981 cgccgaatct ccacgcatcc gctgtggcgc tggttgttgc atatgcagat tgccattatt
    11041 ccgctgtggt tgctgtactc cggcacgctt aacgatctct cgctaatgaa agaatacgcc
    11101 aaccgtcagg atgtgtttga cgacgcgctg gcacaacatc tgacgttgct gtttggtgcg
    11161 gtgctgcctg cgttagtgat tggtgtgccg ttgggcatct ggtgctactt ttccactgcg
    11221 cggcaggggg caattttttc tctgctcaat gtcattcaga ccgtgccttc ggtggcgctc
    11281 tttggcctgt tgattgcgcc gcttgccgcg ctggtgacgg cctttccgtg gctggggaag
    11341 ctcggcatag caggaaccgg aatgacaccc gcactgattg cgctggtgct ctatgccttg
    11401 ctgccgctgg tgcgcggcgt ggtagtaggc ttgaaccaga tcccgcgcga tgtgctggag
    11461 agcgccagag cgatggggat gagcggggcg cagcgattcc tgcatgttca gttaccgctg
    11521 gcgttaccgg tatttctgcg cagcctgcgg gtggtgatgg tgcaaactgt aggtatggcg
    11581 gtgattgcgg cgttaatcgg cgcaggcggt tttggtgcgc tggttttcca ggggctgcta
    11641 agcagcgcca ttgatttagt gttgctgggg gtgatcccgg taattgttct ggcggtgctg
    11701 atcgatgccc tgttcgattt gcttatcgca ctgctgaagg tgaaacgtaa tgattgaatt
    11761 tagccatgtc agcaaactgt ttggcgcaca aaaagccgtt aacgatctta atctcaattt
    11821 tcaggaaggg agtttttcgg tgctgattgg cacatctggc tccggcaaat ccaccacctt
    11881 gaaaatgatt aaccgcctgg tggaacatga cagcggagag atccgctttg ccggagaaga
    11941 aattcgctcg ctgccagtac tggagttgcg ccgccggatg ggctatgcca ttcaatctat
    12001 tggcctgttc ccccactgga gcgtggcgca aaacatcgct accgtgccgc aattacaaaa
    12061 atggtcgcgg gcacggattg acgatcgtat cgacgaatta atgacgctac tggggctgga
    12121 gtcaaatttg cgtgagcgtt atccgcatca gctttccggt ggtcagcagc aacgtgtggg
    12181 agtggcgcgc gcactggctg ccgatccgca agtcttactg atggatgaac cttttggcgc
    12241 actggacccg gtaacgcgcg gcgcgttgca acaagagatg acgcgcattc accgtttgct
    12301 ggggcgcact attgtgctgg tcactcatga tattgatgag gcgctaaggc tggcagaaca
    12361 tctggtattg atggatcacg gtgaagtggt gcagcagggg aatccgctga cgatgctgac
    12421 tcgtccggcg aatgattttg tccgccagtt ttttggacgt agtgaactgg gggtgcgcct
    12481 gctttcgtta cgtagtgtgg cggattacgt gcgtcgcgaa gaacgggcag aaggtgaggc
    12541 actggcagaa gagatgacgc tacgcgatgc gctctccctg tttgtcgcgc ggggatgcga
    12601 ggtgctgccg gtgatgaaca cgcagggcca gccttgcggc acgctgcatt ttcaggatct
    12661 gctggaggag gcgtaagcgt atgaaaatgt tgcgcgatcc gctgttctgg ctcattgctt
    12721 tgtttgtggc actgattttc tggctgcctt acagccagcc gctgtttgct gccttgttcc
    12781 cacaactgcc acgacccgtt tatcagcaag aaagttttgc agctctggca ctggctcatt
    12841 tctggctggt gggaatttcg agtttgtttg cggtgatcat tggcactggt gccggaattg
    12901 ctgtcactcg cccgtggggc gcggaatttc gcccactggt ggaaactatt gccgccgttg
    12961 gacagacttt tccgcctgtc gcagtgctgg cgattgccgt tccggtgatc ggctttggtc
    13021 tgcaaccagc gattatcgcc ttgatccttt acggtgtgct gcccgtcctg caggcgacac
    13081 ttgccgggct gggagcgatc gatgccagcg tgacagaagt tgcgaaaggt atgggaatga
    13141 gtcgtggtca gcgactgcgt aaggtcgagc taccgctggc ggctccggtg attctggcgg
    13201 gcgtgcgaac ttcggtgatt atcaacattg gtacggcgac gatcgcctca acggtaggag
    13261 ccagcacgct gggtacgccc atcatcatcg ggcttagcgg atttaatacc gcgtatgtga
    13321 tccagggggc gttactggtg gcactggcgg cgatcatcgc agaccgcctg tttgaaaggc
    13381 tggtgcaggc gcttagccag cacgcaaaat aaaggtataa cctgcgagca tgacgccacc
    13441 aattccgcct aacgccataa acaggaacag ggcgatgacc ccaattttag ctatgcgcat
    13501 attgcactcc ttatgttaac gaaaggattg tacagtaaag cgcatttgtt aacgaatcat
    13561 taaatgccga gtgggaaaat atcatggcct tgttcttgcc aactggtgag ttgctgctgt
    13621 tgggcggagg ttcgattttc accgcaccac accagcaatg tacggccttc gaatagttca
    13681 gggcgtagtt gattgagcga gtgggcgagg acatcaatgc gccatccttg ttgactggca
    13741 atccagccct ccagccacag acgggtggta tcctgaatat tccagccaac caccagcgca
    13801 tctttaccct gttttttacg tgccgaagcc agacaaatgg cgatgtagtt gatcagtacg
    13861 ccgtcgagga tcgccagcag cgcctggaga gtcggttgtt ggcactgaag ccgtcggcgc
    13921 agaggaataa acagatgtgt ggtgagtgtc tgggcggggt aatcctgacc gcgctctttg
    13981 atccacgttc gcaggctatg cagattgccg ctttgcaggt aggtcagtaa tgtttcttgc
    14041 tgatcgcgcc agccgttctg cacatcaaca ttttcattac tgagcagcat tttaactttg
    14101 ctgacctgca cgccgttgtc gatccagcgt ttgatctcgc ggatacggtc aatatcggca
    14161 tcgttgaaca gtcgatgacc gccgtctgtc cgttgcggtt tcagcaaccc gtaacgcctc
    14221 tgccacgcgc gtaacgtgac agggttaata tcacaaagca acgccacttc accaattgtg
    14281 taaagcgcca tcgtctcacc cttgctcgcg aggtcccggt ttaactttag acgcagtttt
    14341 gcgaaccagg tagttttgcc cgttttttgt gcatctatag ggtgatttta tttttgccag
    14401 gcgattttga gtgatcgtac tcacgaattc tcatttttct gcaagagttc aaagaaagtt
    14461 aaacgcaggc aatgtatgtt acgcgtttta aagggaagtg tggtttgcgg gtatgtacga
    14521 ttttaatctg gtgttgctgc tgcttcagca gatgtgcgtt tttttagtca ttgcgtggtt
    14581 aatgagtaaa acgccattat tcataccgtt aatgcaggtc acggttcgtc tgccgcataa
    14641 atttctctgc tacatcgtct tttccatctt ctgcatcatg ggcacctggt ttgggttgca
    14701 cattgacgat tctattgcca atacccgtgc gataggcgcg gtaatgggcg gcttactcgg
    14761 cggtccggtc gtcggtgggc tggttggtct gaccggcggc ttacatcgat attcgatggg
    14821 gggcatgacc gcgctaagtt gcatgatctc aaccatcgtt gaaggattgc tcggcggcct
    14881 ggtacacagc atcctgatcc gtcgcgggcg cactgataaa gtctttaacc ccattaccgc
    14941 cggtgccgtc acgttcgtcg ctgaaatggt gcaaatgctg atcatcctgg cgatcgcccg
    15001 accttatgaa gatgcggtgc gtctggtgag taatattgct gcgccaatga tggtcaccaa
    15061 taccgtcggc gcggcgctgt ttatgcgtat attgctcgat aaacgcgcga tgtttgaaaa
    15121 atacacttcg gctttttctg ccactgcgct gaaagtggca gcctcgacgg aaggcatttt
    15181 gcgacagggg tttaacgaag tgaacagcat gaaagtggca caggtgctgt atcaggagct
    15241 ggatattggt gcagtcgcga ttaccgatcg agagaaattg ctggccttta ccggaattgg
    15301 tgacgatcac catttacccg gcaaaccgat ttcttcgact tacaccttaa aagcgattga
    15361 aaccggtgaa gtggtctacg ctgatggcaa cgaagtacct tatcgttgct ctttgcatcc
    15421 gcaatgcaaa ctggggtcga cgctggtaat tccgttgcgt ggtgaaaatc agcgggtgat
    15481 gggcaccatc aaattgtatg aagccaaaaa ccgtttattc agttcaatca accgcacgct
    15541 gggcgagggg attgcgcaac tgctttcggc gcagatcctc gccgggcaat atgagcggca
    15601 aaaagcgatg ctcacccagt cagagatcaa actgcttcac gcccaggtga acccccattt
    15661 tttgtttaat gcgcttaaca ccattaaagc ggtgatccgt cgcgacagcg aacaggccag
    15721 ccagctggtg cagtatcttt ccactttttt ccgcaaaaac ttaaagcggc cttcggagtt
    15781 tgttactctc gccgacgaaa ttgaacatgt gaacgcttat ctgcaaattg aaaaggcgcg
    15841 cttccagtcg cggttgcagg tcaacattgc tattccgcaa gaattatccc agcagcaatt
    15901 gcccgcgttt accctgcaac cgatagtgga aaacgccatt aaacatggga catcacaact
    15961 gctggataca gggcgagtgg caatcagcgc ccgacgtgag gggcaacatt tgatgctgga
    16021 gatcgaagac aatgccggtt tgtatcaacc ggtaaccaat gccagtgggc tggggatgaa
    16081 tctggtggat aagcgtttac gtgaacggtt tggcgatgac tatggaataa gcgtcgcctg
    16141 tgagcctgat agttacaccc gaataacgtt acgactacca tggagggacg aggcatgatt
    16201 aaagtcttaa ttgtcgatga tgaaccgtta gcacgggaga acctgcgtgt atttttgcag
    16261 gagcagagcg atattgaaat cgttggagag tgttcaaacg ccgtggaagg gatcggcgcg
    16321 gtgcataaac tgcgcccgga tgtgctgttt ctcgatatcc agatgccgcg catcagtggt
    16381 ctggaaatgg ttgggatgct tgacccggaa catcgcccgt atattgtttt tctcactgcg
    16441 tttgacgaat acgctattaa agcctttgaa gaacatgcct ttgattatct gctgaagcca
    16501 attgatgaag cgcgactgga gaaaacgctg gcgcgattgc gtcaggagcg cagcaagcag
    16561 gatgtttcgc tgttaccgga aaatcaacag gcgctgaaat ttatcccttg tacggggcat
    16621 agtcggattt atttgctgca aatgaaagat gtggcatttg tcagcagtcg gatgagcggt
    16681 gtctacgtta ccagccacga agggaaagag ggctttaccg aattgacatt acgtaccctg
    16741 gaaagtcgta caccactact gcgctgccat cgtcagtatc tggttaacct cgcgcattta
    16801 caggagattc gtctggaaga taacggccag gccgagttga ttttgcgtaa tggcttaacc
    16861 gtgccggtca gccgccgtta tctgaaaagc ttaaaagagg cgattggcct gtaaaagact
    16921 gctaaaatgg ctttttgcct catcaacacc tgaaggcctc atgctaagta acgatattct
    16981 gcgcagcgtg cgctacattt tgaaagccaa taataatgac ctggtgcgta ttctggcgct
    17041 gggtaatgtc gaagccaccg cggaacagat cgccgtctgg ctacgtaaag aagacgaaga
    17101 gggttttcag cgttgtccgg acattgtttt gtcgtcattc ctcaatggcc tgatttatga
    17161 aaaacgcggc aaggatgagt ctgctccggc actggagccg gaacgtcgca ttaataacaa
    17221 catcgtgctg aaaaaattac gcatcgcgtt ttcgctgaaa accgatgaca ttctggcgat
    17281 cctcaccgaa cagcagttcc gcgtttcgat gccggaaatt acagcgatga tgcgtgcacc
    17341 ggatcataaa aacttccgcg aatgcggcga tcaattttta cgttattttc tgcgtggact
    17401 ggcagcgcgc cagcatgtga aaaaaggcta aaaaattggc ggtcatgttt agagcatgac
    17461 cgccaaccga ttatttcact tctttaaaac cagcggcttt catcaccagt tccatttgcg
    17521 ccatagtgat accttttttg gcatcttcag cagaaacgtt gattcctgaa ataccctgca
    17581 gggctttaaa atccactttt tccatatcga tagtcacgtt ttcctgcgcg taggtatctg
    17641 tataggttaa tttttcttca acacccgcga tgtttttgta tttggcgctt aacggctcaa
    17701 gtgtcttggc agcgtcttct ttggtggttg caccaataga agcaaattga attttggttt
    17761 cagaagattg cttaagcacc ttgtcacctt tgtagacata ggtaatggca atttcagtgc
    17821 cgttcagatt ggcgctgaat ttcttcgatt cttctttgtc accgcagcca gcaagagaga
    17881 aaaccagaac agatgcaaca acgagggaaa acagcttatt gaaagccttc atgtaaaact
    17941 ccattttatt taatcaagaa actggtgact ctcaccaggg gctatataga atatgcctaa
    18001 taccgtgacg tgagcagtcc ggaactggag tagaactctt agtaaaaagc actatttcat
    18061 ccttgttgct gaagcatggg gaataattgt tcgcaaagta aaacaccgtt attcattgct
    18121 tctacccgtg cctcgctttc tgtattacga aattgtccca acatatgtgc cagccgataa
    18181 aaaccgaccg cggagaggtc attcgccagc aactctgcct gactaatagc gctctgttcc
    18241 tgatagcgcc agccgttatg gagcagttga ataagtaacg cctggcagcg catcagcaac
    18301 tgatgagcgg tagacggcac aggcaaaacg ctggcagaag gtagcggtgc cacaggcgca
    18361 gtttccgcgt ccagcgccca ggcgcgggtt tttgtcatca tcacccgtgg ttccagtgtc
    18421 aattgcccat caacaaaact gacaaagcca gaaaccagac tcacggggtc gtctgtttgt
    18481 tgcaaaagcg ccgccatgcg ttcaacggca aaaggagaac aggcagatgc cggaagggat
    18541 aacgtcagga gattatcttc accttcgccg ctgattacct gcgcatccag cgtctggcgg
    18601 ctgctatccc aaccgagcga aatacactca gcgaccggca gaataaataa gttatcgacc
    18661 tgattaagag gccgtatgca ggcgggggga cgctggcgta aatattcccg caaagccaca
    18721 atgcccggct ggcgtaacgg cgcgctcaac atttgccagg catcaggcga cagcggcaca
    18781 acgctgctta agcggttgcg ggtagctaac agcagctcgc catcggcact gcgttttgct
    18841 gcttgtgaaa caatttgccc acccgccagt gcgccagcct gaaaactaaa cagccgacgc
    18901 atagctgccg gtgagttttc ctgttcactt cgcggccaac tgcgcgaaag gtgcaaaata
    18961 ctgccggtgt cgggatcggt aaaccagatg cgtaaaccat aatgctcaat atcctgccag
    19021 caacgcatac ctaaagacac cagccgcaga tgatcaagct ttgcttctcc ggcaatgcca
    19081 gagccaacga ccgtgcgcca cggcacagga ggaacttcac caacactgtc gcgccgggcc
    19141 atctcttgtg cgcaatttaa tcgactgttt aatgccgcaa gctgacgtaa gcattctccg
    19201 gcatgatagt ggctggcgcg agtgtggaag gcatcaacgc ttgcccgtag ctgtcgtagt
    19261 gattcactca cccagcgcca gttgcaggcc tctgccgcct gcaatgcgcg gttgaatgct
    19321 gcctcgtagt gaataagcgg ctggctgatg ccgccaagcc ataatgcctg gcttaattgc
    19381 tgaacatatt gacgacacgt ttggccttct tcgctggcaa acggatcgtc agatgatgtg
    19441 acgtgttcgc tgcgcatctg ccagattaaa tggttaaatt ctgcttgctg cgctttggcc
    19501 tcgacgaagg cctgcacagc cagtacgaca tgttcgcaaa gtgtgccttc aatacaatca
    19561 caacgggcga aacgaatact gctacgggaa taaaaacgca catcgctcat cggtaagcgg
    19621 gcagagggaa tttcgcccgg cgcacagaac aactcaatgg tgatgccttt agcgaccagc
    19681 gcctgcgcgc gtttgcgggt ggcatcgggc agggtagcca gttcttccag ccagattgcc
    19741 ggatcccacg cttcttcttt ttccgtaggc tgggcggtag tacaaagtcg ttgataactt
    19801 aacacaagca tcacgcgatg acggcacata ccgctggccc cgcagctgca ctgagcctct
    19861 ttcagtgcct ggccgttcgc cagctgggta cggacaccgt cactgaaggt ggcgattaaa
    19921 gcgctgttct catggctgat ttccgggacg ttgccatttt ccagttcctt aagactgcgc
    19981 ttaacaaaac cggcattgct taacgccgtc agggcctgcg gtgtcagttc taataattcc
    20041 ggacgtagtg aattcatgac tgaagattct ccgcaagcca tgatgccagc tcgcccggtg
    20101 tcatggcggc tatttgtgcg ccgacattta ccagcgcctg ggccgtatcg tggtcatagc
    20161 aaggtgttgc tgtgctatcg agcgctgcca gtcccagcac tttgatgccg ctctggacac
    20221 actttttcac ctgatgcgtc agtaatgatg atgaaccccc ttcgtaaaaa tcgctcacga
    20281 ggataatgac gcttttcgct ggttgttcaa taagttgccg accatactcc acggcactgg
    20341 cgatattggt cccgccgccc aactgtactt tcattaataa ctctaccgga tcggcaacgt
    20401 ctgccgtgag atcaacgacg cttgtgtcaa acgccaccag atgggtacga atgccgggta
    20461 actgccacaa acaggccgcc atcaccgcag agtggatcac cgaatcgacc atcgatccgc
    20521 tttgatcaac cagtaagacc agttgccatt gttcgctttg gcgtttaatg cggctgttaa
    20581 agcgggggga ttcgatatac aacttgccgt gttgcgggtg ccagtgttgc aggttggcgc
    20641 gcagagtact tttgaaaaca aagtttcgcg ccagtggaat aaatgaacgg cgacggcgat
    20701 cgcggacacc agaaaaagcc tggcgaactt cctttgccag tcgcgccata atttcttcaa
    20761 caacctggcg cactatctgg cgggcggcag ccagtacttc gggattcatc agatgtttgg
    20821 tgtgcaaaac ggcgcgtagc aggctttcgg aaggctgcat acgttccagc acgtcgagat
    20881 ttgtcaccac atcttcaatg ccgtagcgca gtacggcatc gctttccagc cgctcaatca
    20941 cctgttgcgg aaacagcgtg tggatactgt tgatccactc aggagtggtg agatttgagc
    21001 cacctaatcc accagagcgt tcaccacgct ggagtcgttc aggatcgcgc ccatacagcc
    21061 actccagcgc gtgatctatc tgccgggcgt tgtcatccag cccacaaagc gtcgtttctg
    21121 ccgcttcgcc aagaattaat cgccagcgtt gtagctcacg ggtggtcaga agatcgttca
    21181 gtttagacat ggaaaactcc ccagtgttgc agcgatgcca gtgcctgctg ttcgagttgt
    21241 tgatgatgtg caatggcttg cggtggacaa tgcaacggca tttgcagtgc cgaaacggga
    21301 agttgcgcca gttgataatg ctcaagcacc tgatgcgcca gcgttccgcg ttctcgtggc
    21361 ggtagccagg ccatcgccgc gcgtaaatcg ggcagggcat tgataaaatc ggcatcactt
    21421 agttgattta aatgactgct gaaaccggcg ataaatgtcg gctgacaggc cagttgatga
    21481 cgggctaatg ccagcaaacc ttgcagcgcc tcgccggatt gtgccgggga taactgcgcc
    21541 agcatcgtca gcgccgcttc ggcactggcg ttgggatgtt ccagacgcat tagtgcgcca
    21601 agaaccgcgc cgcgatccag cgccggggca tgaatcgcct gactgcgtcg ctccagtaag
    21661 gctaccgccg cagaaagcga aacgccggat aaattaacgc cgctatgtag atcgcgcaga
    21721 atatggcaaa gcgcttgcca gctatgcagg tgagcgtgaa actccttttc atccggtctg
    21781 ccgttagatt cacacagcca cagcgtgcga tcgatagccg cgcataacgt cgtttgtaat
    21841 atctgcgcgc cttgcatacc gctaatttca tccagccgcc ataaggcata tagcacttcc
    21901 agcgcctggc ccatttcggc aaattgattt tcctgggcga ttaataatgt gagttgctcc
    21961 agtaattgtt gactgaagga cgccagaccc gctaacgccg cttggctaag acatgtggtg
    22021 atactgccga ttccacccgc gtccagcata tcggcttcta atttatggcg tgcggcttcc
    22081 tggagtgtgg caccaaagca ggcggcctca atcaatgccg catgctggct aagcgggcgg
    22141 gttaatttcc agtgttcttc accgttgcct gcaagtgtca gtgtgcttcc ctgctggcgc
    22201 acaatccctg ggatctccag tattgccagc cgatgtaaca cctgactttg cgctagtcca
    22261 ttggggttaa agcgatttaa ggtaagctcc gccggaaggg agattgcggt acgttccagt
    22321 tcgcaggtga catcttttgg cagaggaggt tgtggcgtag aaggggcaag tttaccgaat
    22381 ccgtcacccg ctaatgtgtc tatcaacgtt agcagaatcg gatcggtgtc gggatgaata
    22441 acaccgcgat agctccacgg caacggcgca ttcagggctt ctttaatcag cgatcctgct
    22501 atggcatcca gccagtcagt gcgtaacggt agtgtatgac cgcgcaactg tgccagtgcc
    22561 atcgcatgca gatgagcggc agccatatcc gcggtcgaag caggcaactt gtgctggcgc
    22621 aaacgggtga gaaccgtttt tagcagttgt tctcccgcct gctgtaagcc ccactgccag
    22681 caccagtttt gccagaccgg ggcaggcatt ccggaaaggt atcctgccag cacatcaagg
    22741 cgcttttcac tgtagggggt gagataacaa cctgtaacgg catctgccag cgacggcaat
    22801 tctggcgtgt taatttcctg cgggcattcg cgccacattt ttgccagtac cggagcgtgc
    22861 cagccaccgc agacaactaa cacgtcgcca ttattttgct gcatcgccca tccaatccag
    22921 cgggccataa aggcttcgcg cagacgattg agagcatctc cgggggagtc gccccgcagt
    22981 tgggcaaaat agtgcgccag tgcagagggt aatgcagttt gctggctttc atcttcgaac
    23041 aagtgatccc acagggtgtc gctgttatcc atgcgggtgg cacgcagcag caaggcctgg
    23101 ctttcctctt gcgtatcagg cgaatcgtcc acttcttcac tctgcgccca gcaaggcaaa
    23161 tcgatgaagt aagtttgtgc ctgaatacga cgtgcggctt gtagcgcctg ccactccggc
    23221 gaaaattcag caaatggcgt ccaggcacca cgcccggggg ctgcaccgtc ctgatactgg
    23281 caataactgt aaatagctac cggaagctgg tgggctaaaa acagttcgtc tacccggtca
    23341 ttaaaatcag ccgggccttc aatcaatacg tatcgtggcc gctggctttc gattaacgat
    23401 ttcaccagcc gggcgcaggc cggactatga tgccggatgc cgacaattaa cggctcgctc
    23461 atgcatcttt cctcacggca ggcggtggcg ggcttgataa taagcctgcc agtgagcttc
    23521 tttatgtgtg gcgactcgtt gttcgaagta acggcgcaga cgagcgcgat cttcttcgtt
    23581 atctttgacg atggttccgg caatgcagtc caccaggtcg gctggctcac ctgcgcgatt
    23641 cgctaaaaac caggcgcgga cgcctacggc gtgggccacg ttcacggctt cagcggtgga
    23701 cataatcgct gttagtgtat ccattgacgt tttcttttcg ccgttggcac gcagatcgcg
    23761 gaaggtgcgg accagtaact ccagtaccgc gtcaggcact ttatgcggaa taccgctatg
    23821 ggccagcaaa cgcgccgaag cactggcgac aagctccagc tcctgggcga aatccataat
    23881 cggaaagacg gtttcaaaat cgaagcgacg ctttagcgcg gcactcatct cattgacgcc
    23941 gcgatcgcgg gtattggcag tggcaataat attaaagcct tcccgcgcat agagctgact
    24001 ggcttcaccg gtgagttccg gcaccgtcat caccctgtca gaaagcatac ctaacagaca
    24061 gtcttgtact tccagcggtg tacgcgttat ctcttcgaaa cggacgattt tgccgtcgcg
    24121 cattccctgg taaagcgggg cagggaccag cgcttccgtt gatgggccat gattgataag
    24181 cagagcgtag ttccagccgt acttgatttg atcttcagtg gtagatgcgc cgccctggat
    24241 ggttaacccg gcatcgccgc taatagcggt tgccagtaat tcagacagga gagattttgc
    24301 ggtgccaggt tcccccacca acatcaaacc gcgtccggtg gcaagagtga ctaacatacg
    24361 ttcgacagcg gagggactaa tcaccacttt acggctaata ttttgcgcgc tatcgccaag
    24421 gataaaagca cgggccgcag gcaaacttaa ctgccaaccg ggcgggcaag gtgcgttatc
    24481 attttgtttt aattttgcca gttcatcggc gtataacaca gcagcaggcg gacgctgcag
    24541 atgattattc tgcggtgaca tatattcatc cctgaaatgt attaatgaaa taaacgatat
    24601 tttacgcgca ataaatgttt ggcgcattag ttgtttgagc ggaaaatatc tggaaagcag
    24661 atcacagtaa ataaaaaaac ctgctggtga ggcaggttct tttatttact attttcaggc
    24721 ctaacaccac agcctgtgca acatcgtgtt ccaacgaacg aattataacc acggctggac
    24781 cccgttgcaa ttaagataat gagatttata atcctgactg ttgggacgtt gcgccggatc
    24841 gaacctattt caagtcctgg ctaccggacg gggggggctg caggtggtgc cctgatccgg
    24901 agtgcaacat cgtggtccaa catacgtaaa ccagtatcga caggcagtgt aagggtaagg
    24961 tgctggtgtt gcgctcctta ataaggagag cggatggact cgctgacaca aaagttaacc
    25021 gtgctcattg ctgtactgga gctattagtg gctctgttac ggttgattga tttgttgaag
    25081 taacgggcaa attgaaacg
//
LOCUS       DAPOAV010000067        24475 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.067, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000067 DAPOAV010000000
VERSION     DAPOAV010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24475
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.067"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(29..105)
                     /locus_tag="RN951_003057"
     tRNA            complement(29..105)
                     /locus_tag="RN951_003057"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(69..71),aa:Arg,seq:acg)
     gene            complement(303..379)
                     /locus_tag="RN951_003058"
     tRNA            complement(303..379)
                     /locus_tag="RN951_003058"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(343..345),aa:Arg,seq:acg)
     gene            complement(383..475)
                     /locus_tag="RN951_003059"
     tRNA            complement(383..475)
                     /locus_tag="RN951_003059"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(439..441),aa:Ser,seq:gct)
     gene            complement(791..976)
                     /gene="csrA"
                     /locus_tag="RN951_003060"
     CDS             complement(791..976)
                     /gene="csrA"
                     /locus_tag="RN951_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HDX2528028.1"
                     /translation="MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHR
                     EEIYQRIQAEKSQQSSY"
     gene            complement(1211..3841)
                     /gene="alaS"
                     /locus_tag="RN951_003061"
     CDS             complement(1211..3841)
                     /gene="alaS"
                     /locus_tag="RN951_003061"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HDX2528029.1"
                     /translation="MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGM
                     NQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDY
                     FKHDAIQFAWELLTSEKWFALPKERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDN
                     KGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQ
                     FNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGATDL
                     SNKSLRVIADHIRSCAFLIADGVMPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKL
                     VGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSGDTLDG
                     ETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASGFGADYNAMI
                     RVDSASEFKGYDHLELNGKVTALFVDGKAVDAINAGQEAVVVLDQTPFYAESGGQVGD
                     KGELKGANFSFAVEDTQKYGQAIGHIGKLAAGSLKVGDAVQADVDEARRARIRLNHSA
                     THLMHAALRQVLGTHVSQKGSLVNDKVLRFDFSHNEAMKPEEIRAVEDLVNAQIRRNL
                     PIETNIMDLEAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRI
                     ISESGTAAGVRRIEAVTGEGAITTVHADSDRLSEVAHLLKGDSNNLADKVRSVLERTR
                     QLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSELSGVEPKMLRTMVDDLKNQLG
                     STIIVLATVAEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTD
                     AAALPAALASVKGWVSAKLQ"
     gene            complement(3969..4469)
                     /gene="recX"
                     /locus_tag="RN951_003062"
     CDS             complement(3969..4469)
                     /gene="recX"
                     /locus_tag="RN951_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HDX2528030.1"
                     /translation="MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKN
                     GPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARIRQELNQKGIS
                     REATEKAMRECDIDWCALARDQATRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQDI
                     WRNFAD"
     gene            complement(4712..5773)
                     /gene="recA"
                     /locus_tag="RN951_003063"
     CDS             complement(4712..5773)
                     /gene="recA"
                     /locus_tag="RN951_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HDX2528031.1"
                     /translation="MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTG
                     SLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDP
                     IYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEI
                     GDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKF
                     YASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELV
                     DLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNS
                     TPDFSVDDSEGVAETNEDF"
     gene            complement(5853..6350)
                     /gene="pncC"
                     /locus_tag="RN951_003064"
     CDS             complement(5853..6350)
                     /gene="pncC"
                     /locus_tag="RN951_003064"
                     /EC_number="3.5.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide-nucleotide amidase"
                     /protein_id="HDX2528032.1"
                     /translation="MTDSELMQLSEQVGQALKARGATVTTAESCTGGWVAKVITDIAG
                     SSAWFERGFVTYSNEAKAQMIGVREETLAQHGAVSEPVVVEMAIGALKAARADYAVSI
                     SGIAGPDGGSEEKPVGTVWFAFATARGEGITRRECFSGDRDAVRRQATAYALQTLWQQ
                     FLQNT"
     gene            complement(6495..7580)
                     /gene="mltB"
                     /locus_tag="RN951_003065"
     CDS             complement(6495..7580)
                     /gene="mltB"
                     /locus_tag="RN951_003065"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic murein transglycosylase B"
                     /protein_id="HDX2528033.1"
                     /translation="MFKRRYVTLLPLFVLLAACSSKPKPTETDTTTGTPSGGFLLEPQ
                     HNVMQMGGDFANNPNAQQFIDKMVNKHGFDRQQLQEILSQAKRLDSVLRLMDNQAPTT
                     SVKPPSGPNGAWLRYRKKFITPDNVQNGVVFWNQYEDALNRAWQVYGVPPEIIVGIIG
                     VETRWGRVMGKTRILDALATLSFNYPRRAEYFSGELETFLLMARDEQDDPLNLKGSFA
                     GAMGYGQFMPSSYKQYAVDFSGDGHINLWDPVDAIGSVANYFKAHGWVKGDQVAVMAN
                     GQAPGLPNGFKTKYSISQLAAAGLTPQQPLGNHQQASLLRLDVGTGYQYWYGLPNFYT
                     ITRYNHSTHYAMAVWQLGQAVALARVQ"
     gene            7836..8399
                     /gene="srlA"
                     /locus_tag="RN951_003066"
                     /gene_synonym="gutA"
     CDS             7836..8399
                     /gene="srlA"
                     /locus_tag="RN951_003066"
                     /gene_synonym="gutA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDX2528034.1"
                     /translation="MIETITHGAEWFIGLFQKGGEVFTGMVTGILPLLISLLVIMNAL
                     INFIGQHRIERFAQRCAGNPVSRYLLLPCIGTFVFCNPMTLSLGRFMPEKYKPSYYAA
                     ASYSCHSMNGLFPHINPGELFVYLGIASGLTTLNLPLGPLAVSYLLVGLVTNFFRGWV
                     TDLTTAIFEKKMGIQLEQKVHLAGATS"
     gene            8396..9355
                     /gene="srlE"
                     /locus_tag="RN951_003067"
                     /gene_synonym="gutE"
     CDS             8396..9355
                     /gene="srlE"
                     /locus_tag="RN951_003067"
                     /gene_synonym="gutE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDX2528035.1"
                     /translation="MTHIRIEKGTGGWGGPLELKATPGKKIVYITAGTRPAIVDKLAQ
                     LTGWQAIDGFKEGEPAEAEIGVAVIDCGGTLRCGIYPKRRIPTINIHSTGKSGPLAQY
                     IVEDIYVSGVKEENITVVGDATPQPSSVGRDYDTSKKITEQSDGLLAKVGMGMGSAVA
                     VLFQSGRDTIDTVLKTILPFMAFVSALIGIIMASGLGDWIAHGLAPLASHPLGLVMLA
                     LICSFPLLSPFLGPGAVIAQVIGVLIGVQIGLGNIPPHLALPALFAINAQAACDFIPV
                     GLSLAEARQDTVRVGVPSVLVSRFLTGAPTVLIAWFVSGFIYQ"
     gene            9366..9737
                     /gene="srlB"
                     /locus_tag="RN951_003068"
                     /gene_synonym="gutB"
     CDS             9366..9737
                     /gene="srlB"
                     /locus_tag="RN951_003068"
                     /gene_synonym="gutB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDX2528036.1"
                     /translation="MTVIYQTTITRIGASAIDALSDQMLITFREGAPADLEEYCFIHC
                     HGELKGALHPGLQFSLGQHRYPVTAVGSVAEDNLRELGHVTLRFDGLNEAEFPGTVHV
                     AGPVPDDIAPGSVLKFESVKE"
     gene            9741..10520
                     /gene="srlD"
                     /locus_tag="RN951_003069"
     CDS             9741..10520
                     /gene="srlD"
                     /locus_tag="RN951_003069"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HDX2528037.1"
                     /translation="MNQVAVVIGGGQTLGAFLCHGLAAEGYRVAVVDIQSDKAANVAQ
                     EINAEYGESMAYGFGADATSEQSVLALSRGVDEIFGRVDLLVYSAGIAKAAFISDFQL
                     GDFDRSLQVNLVGYFLCAREFSRLMIRDGIQGRIIQINSKSGKVGSKHNSGYSAAKFG
                     GVGLTQSLALDLAEYGITVHSLMLGNLLKSPMFQSLLPQYATKLGIKPDQVEQYYIDK
                     VPLKRGCDYQDVLNMLLFYASPKASYCTGQSINVTGGQVMF"
     gene            10625..10984
                     /gene="gutM"
                     /locus_tag="RN951_003070"
     CDS             10625..10984
                     /gene="gutM"
                     /locus_tag="RN951_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HDX2528038.1"
                     /translation="MVSALITVAVIAWCAQLALGGWQISRFNRAFDTLCQQGRVGVGR
                     SSGRFKPRVVVAIALDDQQRIVDTLFMKGLTVFARPQKIPAITGMHAGDLQPDVIFPH
                     DPLSQNALSLALKLKRG"
     gene            11051..11824
                     /gene="srlR"
                     /locus_tag="RN951_003071"
                     /gene_synonym="gutR"
     CDS             11051..11824
                     /gene="srlR"
                     /locus_tag="RN951_003071"
                     /gene_synonym="gutR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucitol operon DNA-binding transcriptional
                     repressor SrlR"
                     /protein_id="HDX2528039.1"
                     /translation="MKPRQRQAAILEYLQKQGKCSVEELAQYFDTTGTTIRKDLVILE
                     HAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKELIAEAAVSFIHDGDSIILDAGST
                     VLQMVPLLSRFNNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENA
                     FEHFTFDKLFMGTDGIDLNAGVTTFNEVYTVSKAMCNAAREVILMADSSKFGRKSPNV
                     VCSLESVDKLITDAGIDPAFRQALEEKGIDVIITGESNE"
     gene            11817..12782
                     /gene="gutQ"
                     /locus_tag="RN951_003072"
     CDS             11817..12782
                     /gene="gutQ"
                     /locus_tag="RN951_003072"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311591.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase GutQ"
                     /protein_id="HDX2528040.1"
                     /translation="MSEALLNAGRQTLMLELQEASRLPERLGDDFVRAANIILHCEGK
                     VVVSGIGKSGHIGKKIAATLASTGTPAFFVHPAEALHGDLGMIESRDVMLFISYSGGA
                     KELDLIIPRLEDKSIALLAMTGKPTSPLGLAAKAVLDISVEREACPMHLAPTSSTVNT
                     LMMGDALAMAVMQARGFNEEDFARSHPAGALGARLLNKVHHLMRRDDAIPQVALAASV
                     MDAMLELSRTGLGLVAVCDAQQQVQGVFTDGDLRRWLVGGGALTTPVNEAMTTGGTTL
                     QAQSRAIDAKEILMKRKITAAPVVDENGKLTGAINLQDFYQAGII"
     gene            complement(12779..14293)
                     /gene="norR"
                     /locus_tag="RN951_003073"
     CDS             complement(12779..14293)
                     /gene="norR"
                     /locus_tag="RN951_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311592.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase transcriptional regulator
                     NorR"
                     /protein_id="HDX2528041.1"
                     /translation="MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALL
                     RYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLI
                     PGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNA
                     LLIEQLESQNMMPGDATPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETG
                     TGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFE
                     MADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREE
                     VLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSAGAR
                     NLLQHYSFPGNVRELEHAIHRAVVLSRATRSGDEVILEAQHFAFPEVTLPPPEAAAVP
                     VVKQNLREATEAFQRETIRQALAQNHHNWAACARMLETDVANLHRLAKRLGLKD"
     gene            14480..15919
                     /gene="norV"
                     /locus_tag="RN951_003074"
     CDS             14480..15919
                     /gene="norV"
                     /locus_tag="RN951_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic nitric oxide reductase
                     flavorubredoxin"
                     /protein_id="HDX2528042.1"
                     /translation="MSIVVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEK
                     NVLIDTVDHKFSREFVQNLRNEIDLADIDYIVINHAEEDHAGALTELMAQIPDTPIYC
                     TANAIDSINGHHHHPEWNFNVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYLTGDA
                     VLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNL
                     PVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGI
                     AETDPRVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLR
                     FRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDQDALELCREHGREI
                     ARQWALAPLPQSTVNTVVKEETSATTTADLGPRMQCSVCQWIYDPAKGEPMQDVAPGT
                     PWSEVPDNFLCPECSLGKDVFDELASEAK"
     gene            15916..17049
                     /gene="norW"
                     /locus_tag="RN951_003075"
     CDS             15916..17049
                     /gene="norW"
                     /locus_tag="RN951_003075"
                     /EC_number="1.18.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavorubredoxin reductase NorW"
                     /protein_id="HDX2528043.1"
                     /translation="MSNGIVIIGSGFAARQLVKNIRKQDATIPLTLIAADSMDEYNKP
                     DLSHVISQGQRADDLTRQTAGEFAEQFNLHLFPQTWVTDIDAEARVVKSQNNQWQYDK
                     LVLATGASAFVPPVPGRELMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDF
                     CRAGKAVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTDSGILA
                     TLDRQRSIEVDAVIAATGLRPETALARRAGLTINRGVCVDSYLQTSNDDIYALGDCAE
                     INGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPELPLHLAGETQRQDLR
                     WQINTERQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLPM"
     gene            complement(17177..19429)
                     /gene="hypF"
                     /locus_tag="RN951_003076"
     CDS             complement(17177..19429)
                     /gene="hypF"
                     /locus_tag="RN951_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyltransferase HypF"
                     /protein_id="HDX2528044.1"
                     /translation="MAKNTSCGVQLRIRGKVQGVGFRPFVWQLAQQLNLHGDVCNDGD
                     GVEVRLLEDPETFLVQLHQHCPPLARIDSVEREPYIWSQLPTEFTIRQSTGGTMNTQI
                     VPDAATCPACLAEMNTPGERRYRYPFINCTHCGPRFTIIRAMPYDRPFTVMAAFPLCP
                     ACDKEYRDPLDRRFHAQPVACPECGPHLEWVSHGEHAEQEAALQAAIAQLKMGNIVAI
                     KGIGGFHLACDARNSNAVATLRARKHRPAKPLAVMLPVADGLPDAARQLLTTPAAPIV
                     LVDKKYVPELCDDIAPDLNEVGVMLPANPLQHLLLQELQCPLVMTSGNLSGKPPAISN
                     EQALEDLQGIADGFLIHNRDIVQRMDDSVVRESGEMLRRSRGYVPDALVLPPGFKNVP
                     PVLCLGADLKNTFCLVRGEQAVLSQHLGDLSDDGIQMQWREALRLMQNIYDFTPQYVV
                     HDVHPGYVSSQWASEMNMPTQTVLHHHAHAAACLAEHQWPLDGGDVIALTLDGIGMGE
                     NGALWGGECLRVNYRECEHLGGLPAVALPGGDLAAKQPWRNLLAQCLRFVPEWQNYSE
                     TASVQQQNWSVLARAIERGINAPLASSCGRLFDAVAAALGCAPATLSYEGEAACALEA
                     LAASCHGVTHPVTMPLVDNQLDLATFWQQWLNWQAPVNQRAWAFHDALAQGFAALMRE
                     QATMRGITTLVFSGGVIHNRLLRARLAHYLADFTLLFPQSLPAGDGGLSLGQGVIAAA
                     RWLAGEVQNG"
     gene            complement(19582..20109)
                     /gene="hydN"
                     /locus_tag="RN951_003077"
     CDS             complement(19582..20109)
                     /gene="hydN"
                     /locus_tag="RN951_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport protein HydN"
                     /protein_id="HDX2528045.1"
                     /translation="MNRFIIADASKCIGCRTCEVACVVSHQENQDCASLTPETFLPRI
                     HVIKGVNISTATVCRQCEDAPCANVCPNGAISRDKGFVHVMQERCIGCKTCVVACPYG
                     AMEVVVRPVIRNSGAGLNVRADKAEANKCDLCNHREDGPACMAACPTHALICVDRNKL
                     EQLSAEKRRRTALMF"
     gene            complement(20258..21268)
                     /gene="ascG"
                     /locus_tag="RN951_003078"
     CDS             complement(20258..21268)
                     /gene="ascG"
                     /locus_tag="RN951_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708521.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator AscG"
                     /protein_id="HDX2528046.1"
                     /translation="MTTMLEVAKRAGVSKATVSRVLSGNGYVSQETKDRVFQAVEESG
                     YRPNLLARNLSAKSTQTLGLVVTNTLYHGIYFSELLFHAARMAEEKGRQLLLADGKHS
                     AEEERQAIQYLLDLRCDAIMIYPRFLSVDEIDDIIDAHSQPIMVLNRRLRKNSSHSVW
                     CDHKQTSFNAVAELINAGHQEIAFLTGSMDSPTSVERLAGYKDALSQHGIALNEKLIA
                     NGKWTPASGAEGVETLLERGAKFSALVASNDDMAIGAIKALHERGVAVPEQVSVIGFD
                     DIAIAPYTVPALSSVKIPVTEMIQEIIGRLIFMLDGGDFSPPKTFSGKLIRRDSLIAL
                     SR"
     gene            21528..22985
                     /gene="ascF"
                     /locus_tag="RN951_003079"
     CDS             21528..22985
                     /gene="ascF"
                     /locus_tag="RN951_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose/arbutin/salicin transporter
                     subunit IIBC"
                     /protein_id="HDX2528047.1"
                     /translation="MAKNYAALARSVIAALGGVDNISAVTHCMTRLRFVIKDDQLIDS
                     PTLKTIPGVLGVVRSDNQCQVIIGNTVSQAFQEVVSLLPGDMQPAQPVGKPKLTLRRI
                     GAGILDALIGTMSPLIPAIIGGSMVKLLAMILEMSGVLTKGSPTLTILNVIGDGAFFF
                     LPLMVAASAAIKFKTNMSLAIAIAGVLVHPSFIELMAKAAQGEHVEFALIPVTAVKYT
                     YTVIPALVMTWCLSYIERWVDRITPAVTKNFLKPMLIVLIAAPLAILLIGPIGIWIGS
                     AISALVYTIHGYLGWLSVAIMGALWPLLVMTGMHRVFTPTIIQTIAETGKEGMVMPSE
                     IGANLSLGGSSLAVAWKTKNPELRQTALAAAASAIMAGISEPALYGVAIRLKRPLIAS
                     LISGFICGAVAGMAGLASHSMAAPGLFTSVQFFDPANPMSIVWVFAVMALAVMLSFIL
                     TLLLGFEDIPVEEATAEARKHQSVQPTVAKEVSLN"
     gene            22994..24418
                     /gene="ascB"
                     /locus_tag="RN951_003080"
     CDS             22994..24418
                     /gene="ascB"
                     /locus_tag="RN951_003080"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase AscB"
                     /protein_id="HDX2528048.1"
                     /translation="MSVFPEGFLWGGALAANQSEGAFREGGKGLTTVDMIPHGEHRMA
                     VKLGLEKRFQLRDDEFYPSHEATDFYHRYKEDIALMAEMGFKVFRTSIAWSRLFPQGD
                     EITPNQQGIAFYRSVFEECKKYGIEPLVTLCHFDVPMHLVTEYGSWRNRKLVEFFSRY
                     ARTCFEAFDGLVKYWLTFNEINIMLHSPFSGAGLVFEEGENQDQVKYQAAHHQLVASA
                     LATKIAHEVNPQNQVGCMLAGGNFYPYSCKPEDVWAALEKDRENLFFIDVQARGAYPA
                     YSARVFREKGVTIDKAPGDDEILKNTVDFVSFSYYASRCASAEMNANNSSAANVVKSL
                     RNPYLQVSDWGWGIDPLGLRITMNMMYDRYQKPLFLVENGLGAKDELAANGEINDDYR
                     ISYLREHIRAMGEAIADGIPLMGYTTWGCIDLVSASTGEMSKRYGFVYVDRDDAGNGT
                     LTRTRKKSFWWYKKVIASNGEDLE"
BASE COUNT         5732 a         6718 c         6293 g         5732 t
ORIGIN      
        1 cgctactaaa gccatatcaa gtaagagatg gtgcatccgg gaggattcga acctccgacc
       61 gctcggttcg tagccgagta ctctatccag ctgagctacg gatgcatcgg gaaacttact
      121 ttactgcaga ttttttaata ccgctactaa agccgtatca agtaagaggt ggtgcatccg
      181 ggaggattac tcgccttgcg gctcgccctt cgggccgttg ctaaagcaac gttatcctcc
      241 ctggtgcctg cggttatacc gccacctctt ccataccttc atcgctgaaa gtacgtagaa
      301 tatggtgcat ccgggaggat tcgaacctcc gaccgctcgg ttcgtagccg agtactctat
      361 ccagctgagc tacggatgca aatggcggtg aggcggggat tcgaaccccg gatgcagctt
      421 ttgaccgcat actcccttag caggggagcg ccttcagcct ctcggccacc tcaccacacg
      481 cctcttacga gtgcttcgaa gaacttgttt atcgctcatc gtcgctgcgt ggcgcacata
      541 ttactttctg agacttataa gtcaaacaat ttttcctaca cttttatcgt ttgcacactt
      601 cacgttcaat tagtctgtaa aaacgtcaaa aagagtgttt tatcaacaga aaaatggagg
      661 tctgacagat agtagtaatg caaaaaaatg gagacttaag ttgaatgaac gggagtaaag
      721 cgaaaagact atagagtgaa ggagaaattt tgagggtgcg tctcaccgat aaagatgaga
      781 cgcggaaaga ttagtaactg gactgctggg atttttcagc ctggatacgc tggtagatct
      841 cttcacggtg aacagaaact tccttcgggg catttacgcc aatacgtacc tggttgccct
      901 ttacccctaa aactgtcacg gtgacctcat ccccaatcat gagggtctca ccaactcgac
      961 gagtcagaat cagcattctt tgctccttga aagattaaaa gagtcgggtc tctctgtatc
     1021 ccggcattat ccatcatata acgccaaaaa gtaagcaatg acaaacacat tacatgtaag
     1081 cagtcatggc attacattct gttaaaccta agtttagccg atatacacaa cttcaacctg
     1141 actttatcgt tgtcgatagc gttaatgcga atgccgtgaa gcgagtccac ggcattgcct
     1201 gacgcttata ttattgcaat ttcgcgctga cccagccttt cacactggct aacgctgcag
     1261 gtaaggccgc agcatccgta ccaccggctt gcgccatgtc aggacgtcca ccacccttgc
     1321 cgcccacctg ctgagcgacc ataccaatca gttcccctgc tttcacacga tctgtgacgt
     1381 ccttagatac gcctgcaatc agagaaacct taccttcggc taccgttgcc agcacgataa
     1441 ttgtcgaccc cagctgattt tttaaatcgt caaccatggt acgcaacatt ttcggctcaa
     1501 caccgctaag ctcgctaacc aacagcttaa caccattaac atcaattgcc ttactggaaa
     1561 gatttgcgct ctcctgtgcg gcagcttgtt ctttaagctg ttgtagttct ttttctaact
     1621 gacgcgtacg ttccagtact gagcgcactt tatccgccag attattgcta tcgcctttca
     1681 gcagatgcgc gacttcgctt aagcgatcgc tgtctgcatg aacggtggtg atagcgcctt
     1741 ctccggttac cgcttcgata cgacgaacgc ctgcagcagt acccgattca gagatgatgc
     1801 ggaacagacc aatatcacca gtgcggctgg cgtgagtacc gccacacagc tcggtggaga
     1861 aatcgcccat gctcagcacg cgtacacgct catcatactt ctcgccgaac agcgccatcg
     1921 cacctttcgc tttcgccgct tcgagatcca tgatgttggt ttcgatcggc aaattgcgac
     1981 gaatctgtgc gttcaccagg tcttcgaccg cacgaatctc ttccggtttc atcgcttcgt
     2041 tgtgtgagaa gtcgaagcgc agcaccttgt cgttaaccag tgaacctttc tgcgatacat
     2101 gagtccccag aacctggcgc agcgcagcgt gcatcaggtg cgttgcggag tgattcagac
     2161 gaatacgggc gcgacgagcc tcatcaacat cagcctgcac agcgtcgccc actttcagag
     2221 aacccgcagc aagtttaccg atgtgaccaa tcgcctggcc gtatttctgc gtatcttcca
     2281 ccgcgaagga gaagttagcg cctttcagtt cgcctttatc accaacctga ccgccggatt
     2341 ccgcatagaa tggtgtttga tccagcacga ccacagcttc ctggcctgca ttgattgcat
     2401 caaccgcttt accatcaaca aacagcgcgg tcactttgcc gttcagttcc agatggtcat
     2461 agcctttaaa ttcagatgca ctatcaacac ggatcattgc gttgtaatcg gcaccaaagc
     2521 cgctggcttc gcgcgcgcga cgacgctgct cttccattgc tgcttcaaaa ccagcttcgt
     2581 caactttgat gttgcgctca cgacaaacat cagccgtcag gtcaaccggg aagccatagg
     2641 tgtcgtacag acggaaagcc gtttcaccat ccagcgtatc accagaaagt tttgccagct
     2701 cttcatccag caacgccaga ccgcgctcca gagtacgggc aaactgctct tcttcagtct
     2761 tcagcacctg ctcaacctgc gcctgctggc gtttcaggtc ttcacccgca gagcccataa
     2821 cgtcgatcag cggaccaacc agtttgtaga agaaggtttc tttcgcgccg agcatattgc
     2881 cgtgacgcac tgcgcgacga atgatacgac gcagtacata accacggttt tcattggacg
     2941 gcattacgcc atccgcgatc aggaacgcac aagaacgaat gtggtcagcg attacgcgca
     3001 gcgatttatt gctcagatcg gtcgcgccag tgactttcgc taccgcctgg atcaacgtgc
     3061 ggaacaggtc gatgtcatag ttagagttaa cgtgttgcag caccgcagca atacgctcca
     3121 gacccatacc ggtatctaca gacggcttcg gcagcggttc catcgtgcca tctgcctggc
     3181 ggttgaactg catgaagacg atgttccaga tctcaatgta gcggtcgccg tcttcttccg
     3241 gacttcccgg agggccaccc caaatgtggt cgccgtgatc gtagaagatt tcggtgcacg
     3301 ggccgcacgg accagtgtca cccatctgcc agaagttgtc agatgcgtat ggcgcacctt
     3361 tgttatcgcc gatgcgaata atacgttcgc gcgggatccc gacttctttt tcccagattt
     3421 cgtaggcttc gtcgtcgctt tcatagacgg taacccacag acgctctttc ggcagggcaa
     3481 accatttttc gctggtcagc agttcccatg caaactgaat ggcatcgtgt ttgaaatagt
     3541 cgccgaagct gaagttgccc agcatttcga agaaggtatg gtgacgcgcg gtgtaaccga
     3601 cgttttccag gtcgttgtgt ttaccacccg cacgcacgca gcgttgggaa gtggtagcgc
     3661 gggaataatt acgcttgtcg agcccaagga acacatcctt gaactggttc atcccggcgt
     3721 tggtaaacaa caaagttggg tcgttatggg gtaccaggga gctgctggca actacctgat
     3781 gtcccttact atggaaaaag tcgagaaacg cctgacggat ctcagcggtg ctcttgctca
     3841 taattatcct gaaatcaagc taacgaaata tcgccaccag ctccagcgtg tcttaaccgc
     3901 cgggctggta actgaaaagt gggaataaga taagttttct tgactgggaa gtaaaatacc
     3961 gtatgcgttc agtcggcaaa atttcgccaa atatcctgga tatcttccat cagatagcca
     4021 cgatagagca gaaaacgctg gatcttaact ttttctgaaa agacagttgg caaaggttca
     4081 ccatattttc gcgtcgcctg atcgcgcgcc agtgcgcacc agtcgatgtc acattcacgc
     4141 atcgcttttt ctgtcgcttc gcgggaaata cctttctgat tcagttcctg acgaatacgt
     4201 gcaggtccat aacctttgcg gctacggctg gcgataaagc gcgcaacaaa tcggctgtca
     4261 tcgagatagc catgttcatg gcaccaggca ataacgcgct cgtaatcttc tgccgtagca
     4321 tcaatctctt ctgggccatt tttgcccata atcggtgccg cgagtttacg tcgcagttct
     4381 tgctcactgt gatcgcgcac cgccagaatg cgtaccgcac gatccaacag gcgagcatat
     4441 gccgggcgac gggacgttga ttctgtcatg gcatatcctt acaacttaaa aaagcaaaag
     4501 ggccgcagat gcgacccagg ttttgctgat aaacagattt aatagtcaat gagtgtgcag
     4561 aatgttcccg caggcccaat tcgttagagg atcgaggtga gagtaatttt tcacgccagt
     4621 gctggcctgt tcccctcacc ctaaccctct ccccaaaggg gcgaggggac cgtccgtgca
     4681 cacattatct attatcatca ataacgaacg attaaaaatc ttcgttagtt tctgctacgc
     4741 cttcgctgtc atctacagag aaatccggcg ttgagttcgg gttgctcagc agcaactcac
     4801 gtactttctt ctcgatctct ttcgcggttt ccgggttatc tttcagccag gcagttgcat
     4861 tcgctttacc ctgaccgatc ttctcacctt tgtagctgta ccacgcgcct gctttctcga
     4921 tcagcttctc ttttacgccc aggtcaacca gttcgccgta gaagttgata ccttcgccgt
     4981 agaggatctg aaattcagcc tgtttaaacg gtgcagcgat tttgttcttc accactttca
     5041 cgcgggtttc gctacccacc acgttttcgc cctctttcac cgcgccgata cgacggatgt
     5101 cgagacgaac agaggcgtag aatttcagcg cgttaccacc ggtagtggtt tccgggttac
     5161 cgaacatcac accaattttc atacggatct ggttgatgaa gatcagcagc gtgttggact
     5221 gcttcaggtt acccgccagc ttacgcatcg cctggctcat catacgtgcc gcaaggccca
     5281 tgtgagagtc gccgatttcg ccttcgattt ccgctttcgg cgtcagtgcc gccacggagt
     5341 caacgacgat aacgtctact gcgccagaac gcgccagggc gtcacagatt tccagtgcct
     5401 gctcgccggt gtccggctgg gagcacagca ggttatcgat atcgacgccc agtttacgtg
     5461 cgtagattgg gtccagcgcg tgttcagcat cgataaacgc acaggtttta ccttcacgct
     5521 gcgctgcggc gatcacctgc aacgtcagcg tggttttacc ggaagattcc ggtccgtaga
     5581 tttcgacgat acggcccatc ggtagaccac ctgccccaag cgcgatatcc agtgaaagcg
     5641 aaccggtaga gatggtttcc acatccatgg aacggtcttc acccaggcgc atgatggagc
     5701 ctttaccaaa ttgtttctca atctggccca gtgctgccgc caacgctttc tgtttgtttt
     5761 cgtcgatagc catttttact cctgtcatgc cgggtaatac cggatagtca atatgttctg
     5821 ttgaagcaat tatactgtat gctcatacag tatcaagtgt tttgtagaaa ttgttgccac
     5881 aaggtctgca atgcatacgc agtagcctga cgacgcaccg catcacggtc gccgctgaag
     5941 cattcccgcc gggtaatgcc ttcaccgcgg gcagtggcaa aagcaaacca gacggtgccg
     6001 acaggcttct cttcactgcc gccatccggc ccggcgatac cactaataga cacggcataa
     6061 tcagcacgag ccgctttcag tgcgcctatc gccatttcca ccacgacggg ttcactcacc
     6121 gcgccatgct gcgccagcgt ctcttcgcgt acgccgatca tctgcgcttt ggcttcgtta
     6181 ctgtaggtga caaatccgcg ttcaaaccag gcggagctac cggcaatatc ggtaatcact
     6241 ttcgctaccc aaccaccggt acaagactcg gcagttgtta cggttgcgcc acgggctttc
     6301 agcgcctgcc caacctgttc acttaactgc atcagttcac tgtcagtcat cacaacctct
     6361 gtcagtcaaa aatttatgcc ggacaagata gcactttcgt caggaagatg gtgttggcgt
     6421 tgcaatttta cgaggaggat tcagaaaaaa gctgattagc cagagggaag ctcacgcccc
     6481 cctcttgtaa atagctactg tactcgcgcc agcgccacgg cttgtcctaa ctgccagacc
     6541 gccattgcgt aatgggtgct gtggttgtaa cgggtgatgg tgtagaagtt cggcagaccg
     6601 taccagtact ggtagccggt gccaacatcc agacgcagca ggctggcttg ttgatggttg
     6661 cccagcggct gctgtggcgt taaacctgcg gcggcaagct gcgaaatgct gtacttagtt
     6721 ttgaagccat ttggcaagcc tggagcctga ccgtttgcca ttaccgcgac ctgatcgcct
     6781 ttcacccagc cgtgcgcttt gaaatagttc gccacgctac cgatcgcatc aaccggatcc
     6841 cacaggttga tatgcccgtc gccgctgaaa tctaccgcat attgtttgta agacgacggc
     6901 ataaactgtc cgtagcccat cgccccggca aaggaacctt tcagattgag cggatcgtcc
     6961 tgctcgtcgc gcgccatcaa caggaaggtt tccagctcgc cagagaaata ctccgcgcgg
     7021 cgtgggtagt taaatgacag cgttgccagc gcatcgagga tgcgagtttt ccccatcacg
     7081 cgcccccagc gggtttcaac gccgataatc ccgacgataa tttccggcgg tacgccatac
     7141 acctgccacg cgcgattcaa cgcatcttca tactgattcc agaaaaccac accgttctgc
     7201 acgttgtccg gcgtaataaa ttttttgcga taacgcagcc atgcgccgtt cggacctgat
     7261 ggcggtttca ccgatgtggt tggtgcctgg ttatccatca gccgcagtac cgaatccaga
     7321 cgtttcgcct gggagagaat ttcctgcaac tgctgacgat cgaaaccgtg tttgttcacc
     7381 attttgtcga tgaactgctg ggcattcggg ttattagcga aatcgccgcc catctgcatc
     7441 acattgtgct gcggctcaag caggaagccg ccagacggcg ttccggtggt cgtatcagtc
     7501 tcagtaggtt ttggcttgct gctacaggcg gcaagcaaca caaaaagggg aagcaatgtt
     7561 acataacgac gcttgaacat gaggggtcca tttaacagat tcaaccaggg gcaagtatgg
     7621 taaagcatca cgccccgcac aaggaagcgg tagtcactgc ccgatacgga ctttacataa
     7681 ctcaactcat tcccctcgct atccttttat tcaaactttc aaattaaaat atttatcttt
     7741 cattttgcga tcaaaataac acttttaaat ctttcaatct gattagatta ggttgccgtt
     7801 tggtaataaa acaataaatc ctgaaggaga gaacaatgat agaaaccatt actcatggtg
     7861 cagagtggtt tatcgggctg ttccaaaagg gcggagaggt gtttaccggg atggtgaccg
     7921 gcattcttcc gctgttgatt agcctgctgg ttatcatgaa cgcactgatt aattttatcg
     7981 gtcagcatcg tattgaacgt tttgctcaac gttgcgccgg taaccctgtt tcccgttacc
     8041 tactgttacc gtgcattggc acgtttgtct tttgcaatcc gatgacccta agcctgggtc
     8101 gctttatgcc ggaaaagtac aaacccagct actacgcggc ggcctcttat agctgccact
     8161 caatgaatgg cctcttcccc catatcaacc ctggcgaact gtttgtttat cttggcattg
     8221 ccagcggtct gacaacgctg aacctgccac ttggcccact ggcggtgagt tatctgctgg
     8281 ttggtctggt caccaatttc ttccgcggct gggtgaccga tctgaccacc gccatttttg
     8341 agaaaaagat gggcattcaa cttgaacaaa aagttcacct ggcaggagca acatcatgac
     8401 gcatattcgg atcgaaaaag gaacgggtgg ctggggcggc ccgcttgagc tgaaagccac
     8461 gccgggaaaa aaaatcgtct atatcaccgc cggtacccgg cctgcgattg ttgacaaact
     8521 ggcacagctt actggctggc aggctattga cggatttaaa gaaggtgaac ccgcggaggc
     8581 ggaaattggt gtcgcggtaa tcgactgtgg cggcacatta cgctgcggca tctatccgaa
     8641 acgacgtatt cccaccatta atatccactc gacgggcaag tccggtccgc tggcgcagta
     8701 cattgtggaa gatatttatg tctctggcgt aaaagaagaa aacatcactg tagtaggtga
     8761 tgcgacacca caaccctctt ccgtgggccg tgactatgac accagtaaga aaatcaccga
     8821 acaaagcgat ggtttactgg cgaaggtggg aatgggcatg gggtccgccg ttgcggtgct
     8881 gtttcaatct ggtcgtgaca ccatcgacac tgtattaaaa accattctgc cgtttatggc
     8941 attcgtctcg gcgctcattg gcatcattat ggcttctggc cttggtgact ggattgccca
     9001 cggtcttgct ccgctggcga gccatccact gggtctggtc atgctggcgc tcatctgttc
     9061 cttcccactg ctttcacctt tcctcggccc aggcgcagtt atcgcacagg ttatcggcgt
     9121 attgattggc gtgcagattg gtctcggcaa tattccgccg catctggctt taccggcact
     9181 gtttgccatc aacgcgcagg cggcctgcga cttcatcccg gtcggtttgt cgctggcgga
     9241 agcccgtcag gacacggttc gcgtcggtgt cccttctgta ctggtgagcc gctttttaac
     9301 cggcgcgccg actgtactga tcgcctggtt tgtctccggt tttatctatc aatagaggct
     9361 gaaacatgac cgttatttat cagaccacca tcacccgtat cggcgcgagt gccattgacg
     9421 ccctcagtga ccagatgctc atcacctttc gtgaaggcgc gcctgcggac ctcgaagagt
     9481 attgcttcat tcattgccac ggcgagttga aaggtgcact ccatcccggt ttgcaatttt
     9541 cactcgggca gcatcgctat ccggtgaccg ctgttggcag cgtggcggaa gacaaccttc
     9601 gcgaactggg tcatgtcacc ctgcgcttcg atggtttaaa cgaagcggaa tttccgggca
     9661 ctgtccatgt ggcaggccct gtccccgacg atatcgcgcc gggatcggtt ttgaagtttg
     9721 aatctgttaa ggagtaaaaa atgaatcagg ttgccgttgt catcggtggt gggcaaacct
     9781 taggcgcgtt cctgtgccac ggtctggctg ccgaggggta tcgcgtcgcg gttgtcgata
     9841 ttcagagcga caaagccgca aatgtggcac aagaaattaa cgccgaatat ggtgaaagta
     9901 tggcgtacgg ttttggtgct gacgccacta gcgagcaaag cgttctggcg ctctctcgtg
     9961 gggtagatga aatctttggt cgcgtggatt tgctggtcta cagcgccgga atagcaaaag
    10021 cagcctttat cagcgacttc cagctcggcg attttgaccg ttcgctacag gtgaatctgg
    10081 tgggttattt cctgtgtgcg cgtgaatttt cgcgtttgat gatccgcgac gggattcagg
    10141 ggcgcattat tcagatcaac tcgaaatccg gcaaagtggg cagcaaacac aactctggct
    10201 acagcgcagc gaaatttggt ggcgtcgggc tgactcaatc actggcgctg gatctggcgg
    10261 agtacggcat tacggtgcat tcactgatgc tcggtaacct gctgaaatcg ccgatgttcc
    10321 agtcactgtt gccacaatac gcgaccaagc tgggtatcaa accggatcaa gtcgagcagt
    10381 attacatcga caaagtaccg ctcaaacgcg gctgcgatta tcaagatgtg ctgaatatgc
    10441 tgctgttcta cgccagtcct aaggcgtcgt actgcaccgg acagtcgatc aatgtcaccg
    10501 gcggtcaggt gatgttctga tcaacagcgg agatccatta aggatctccg tgagactata
    10561 gaatgcctga tgcgctacgc tcatcaggca tacaggactt ccgccactac attaaggaaa
    10621 agttatggta tccgcactca tcaccgtcgc cgttatcgcc tggtgtgcgc aactggcctt
    10681 aggcggctgg caaatttctc gttttaaccg tgccttcgac acactatgcc agcaagggcg
    10741 ggttggcgtg ggccgttcca gcgggcgctt taaaccgcgg gtcgtggtcg ccatcgcgct
    10801 ggacgatcag cagcgcatcg tcgacacctt gtttatgaaa ggactgaccg tcttcgcccg
    10861 accgcaaaaa attcccgcaa ttaccggtat gcatgcgggt gatttacagc ccgatgtgat
    10921 ctttccccat gatccactat cacagaatgc tctatcattg gcgcttaaac tgaaacgtgg
    10981 ataatttcgt tgtgaatgtt acttgcttgc gaagttatca ttttgaaacc taaatcaggt
    11041 aatcacgccc atgaaacctc gtcagcgtca ggccgccatt ctggagtatc tgcaaaagca
    11101 gggtaaatgc tcggttgaag aattggcgca atactttgac accacaggca caaccattcg
    11161 caaagatctg gtcattctgg aacatgccgg aaccgtcatt cgtacttatg gcggagtggt
    11221 gttgaataaa gaggaatccg atccgcctat cgatcataaa acgctcatca acacccacaa
    11281 gaaagagctg attgcagaag ctgccgttag ttttattcat gatggcgact caataattct
    11341 tgatgctggc agtaccgttt tgcagatggt ccccctgctc tcgcgcttta ataacatcac
    11401 ggtgatgacc aacagtctgc atatcgtcaa tgcgctatct gaactggata acgaacaaac
    11461 catcctgatg ccaggcggaa catttcgcaa aaaatcggcc tcatttcacg ggcaactggc
    11521 agagaatgcc ttcgagcatt tcaccttcga caaattattc atgggtactg acggcatcga
    11581 tctcaatgcg ggcgtaacca ccttcaacga ggtctatacc gtcagtaagg caatgtgcaa
    11641 tgccgcgcgc gaagtgattt taatggcgga ctcatcaaag tttggccgta aaagccccaa
    11701 cgtagtttgc agtcttgaaa gcgtcgataa gctgattacc gacgcaggta tcgatccggc
    11761 gtttcgtcag gcgctggaag agaaagggat cgatgtgatc ataaccggag agagcaatga
    11821 gtgaagcact actgaacgcg ggacgtcaga cgttaatgct ggagttgcag gaagcaagcc
    11881 gtttaccgga acgtctgggc gatgattttg ttcgcgccgc caatatcatc ctgcactgcg
    11941 aaggcaaagt ggtggtttcg ggaattggca aatcgggcca cattggtaag aaaatcgccg
    12001 caacacttgc cagtaccggc acaccggctt tttttgtcca tccggcagaa gcactgcacg
    12061 gcgatctggg gatgattgaa agccgcgatg tgatgctgtt tatctcttac tccggtggcg
    12121 cgaaggaact ggatctgatt attccgcgtc tggaagataa atctatcgcg ctgctggcga
    12181 tgaccggcaa accgacgtca ccgctgggcc tggcggcaaa agcggtgctg gatatctccg
    12241 tagaacgcga agcctgcccg atgcaccttg cgccgacctc cagcaccgtc aataccctga
    12301 tgatgggtga cgcgctggcg atggcggtca tgcaggcgcg cggttttaat gaagaagatt
    12361 ttgcccgctc ccacccagct ggggcactgg gcgctcgctt gctgaataaa gtgcatcatc
    12421 tgatgcgccg tgatgacgct atcccgcagg tagcgttagc cgccagcgtg atggatgcga
    12481 tgctggagct cagccgcacc ggtctggggc tggtggcggt atgtgacgct caacaacagg
    12541 tacaaggcgt ctttaccgac ggcgatttac gtcgctggct ggttggcggc ggcgcactca
    12601 ccacgccagt taatgaagcg atgacgacag gcggcaccac attacaggcg caaagccgtg
    12661 ccatcgacgc caaagagatc ctgatgaagc gcaaaatcac tgccgcaccg gtggtagatg
    12721 aaaacggcaa actcaccggc gcaattaact tgcaggattt ctatcaggcc gggattattt
    12781 aatccttcaa tcccagacgt ttcgccagcc gatgcaggtt ggcgacgtca gtttccagca
    12841 ttcgcgcgca ggcagcccag ttgtgatgat tttgtgccag tgcctggcga atggtttcac
    12901 gctggaacgc ttctgtcgct tcacgcagat tttgcttaac aacgggcacc gctgccgctt
    12961 ctggcggcgg caacgtcacc tcaggaaaag caaaatgttg cgcctcaaga atcacttcat
    13021 cgccgctgcg agtggctctc gacagtacta ccgcccgatg aatagcatgt tccagttcgc
    13081 gcacgttccc cggaaaactg tagtgttgca gtaaatttcg cgccccggca cttaatacca
    13141 cgcgggagag ccccagccgc aaacgacact gctcgcagaa ataccccgcc agcagaatga
    13201 catcatcgcc ccgctcacgc agcggcggca ccgaaagtgg aaacacgctc aggcgatgaa
    13261 acaagtcagc gcgaaatcgc cctgccagta cctcttcgcg taagtcgcgg ttagtcgccg
    13321 ccagcacgcg cacatcgacc cgcaaactgc ggtcatcgcc aacgcgctga atatcgccat
    13381 actgcaacac tcgcagcaac ttggcctgca aagccaacga caactcgccg atctcatcga
    13441 gaaacagtgt gccgttatcc gccatttcaa acttcccgct gcggttactg atagcgccag
    13501 taaacgcccc tttcacatgc ccgaacaact cactttccgc cacactttcc ggcagtgcgg
    13561 cacagttgag atagaccagc ggattcaccg cccgtggcga ggcttcatga atcgctttcg
    13621 ccaccagctc cttaccggtt cccgtctcac cgctgatcag gacgttgaga tcggacgccg
    13681 ccacaatctc aatctctttt ttcagttgcg tcatgccagg ggacaagcca atcatctgcg
    13741 tctgtttcac cgcttcaaac ggcgtggcat cgcctggcat catattctgg ctttccagtt
    13801 gttcaatcag caacgcattg cttaacgctc ccgccgccag cgcagcaatc agccgtagct
    13861 cttcgtcgct gaaaacatcg aactgatcgg gctgcatccc gtcgagcgtc agtgcgccga
    13921 tcaggttttg cccggcaaac aatggcagac caacgcaggc gtgaaccttc agactctcct
    13981 gcccaggaat caaaccgtca tagggatcgg gcaattcgct gtctgcagga aagcgcacca
    14041 cgtccccggc gcgggcaatc gcttcaagcc gtggatgccc ttccagcgca aagcgtctac
    14101 cgagtacatc ctttgccaga ccgtcgatgg caagcggaat aaactgccgc gaatcgtaac
    14161 gtagcaacgc agacgcatcg cactccagca cctgacgtag cgtggtgatc aggcgctgaa
    14221 aacgatcctg atgaccaatc ccacgctgca attcgatggc gatattcgcc agcacatcaa
    14281 cggaaaaact catctttgcc tcactgtcaa tttgactata gatattgtca tatcgaccat
    14341 ttgattgata gtcattttga ctactcatta atgagcatac ttttatttat atagtaaaaa
    14401 caatcagata aaaaactggc acgcaatctg caattagcaa gacatctttt tagaacacgc
    14461 tgaataaatt gaggttgcta tgtctattgt ggtgaaaaat aacattcatt gggttggtca
    14521 acgtgactgg gaagtgcgtg attttcacgg cacggaatat aaaacgctgc gcggcagcag
    14581 ttacaacagc tatctcatcc gcgaagaaaa aaacgtgctg atcgacaccg tcgaccataa
    14641 attcagccgc gaatttgtgc agaacctgcg taatgaaatc gatctggcgg atatcgatta
    14701 catcgtgatt aaccatgcag aagaggacca cgctggggcg ctgaccgaac tgatggcgca
    14761 aattcccgat acgccgatct actgtactgc caacgctatc gactcgataa atggtcatca
    14821 ccatcatccg gagtggaatt ttaatgtggt gaaaactggc gacacgctgg atatcggcaa
    14881 cggcaaacag ctcatttttg tcgaaacacc aatgctgcac tggccggaca gcatgatgac
    14941 ttacctgaca ggcgacgcgg tgctgttcag taacgatgct ttcggtcagc actactgcga
    15001 cgagcatctg ttcaacgatg aagtggatca gacggagctt ttcgagcagt gccagcgtta
    15061 ctacgccaat atcctgacgc cgttcagccg cctggtaacg ccgaaaatta ccgagatcct
    15121 gggctttaac ttaccagtcg atatgatagc cacttcccac ggcgtggtat ggcgcgataa
    15181 cccgacgcaa attgtcgagc tgtacctgaa atgggcggct gattatcagg aagacagaat
    15241 caccattttc tacgacacca tgtcgaataa cacccgcatg atggctgacg ctatcgccca
    15301 ggggattgcg gaaaccgacc cacgcgtggc ggtgaaaatt ttcaacgtcg cccgaagcga
    15361 taaaaacgaa atcctgacta atgtcttccg ctcaaaaggc gtgctggtcg gcacttcgac
    15421 gatgaataac gtgatgatgc cgaaaatcgc cgggctggtg gaggagatga ctggtttacg
    15481 cttccgtaac aaacgcgcca gtgctttcgg ctctcacggc tggagcggcg gtgcggtgga
    15541 tcgcctttcc acgcgcctgc aggatgcggg tttcgaaatg tcgctcagcc tgaaagccaa
    15601 atggcgacca gaccaggacg ctctggagtt atgccgtgaa cacggtcgcg aaatcgcccg
    15661 tcagtgggcg ctcgcgccgc tgccgcagag cacggtgaat acggtagtta aagaagaaac
    15721 ctctgccacg acgacggctg acctcggccc acgaatgcag tgcagcgtct gccagtggat
    15781 ttacgatccg gcaaaaggcg agccaatgca ggacgttgcg ccaggaacgc cgtggagtga
    15841 agtcccggat aacttcctct gcccggaatg ctccctcggc aaagacgtct ttgacgaact
    15901 ggcatcggag gcaaaatgag taacggcatt gtgatcatcg gttcgggctt cgccgcccgc
    15961 caactggtga aaaatattcg caaacaggac gccactattc cattaaccct gattgccgcc
    16021 gacagcatgg atgagtacaa caaacctgac ctcagccatg ttatcagtca ggggcaacgt
    16081 gccgatgacc ttacccgcca gacggcgggt gaatttgccg agcagtttaa tctgcacctg
    16141 tttccacaaa cctgggtgac ggatatcgat gccgaagccc gtgtggtgaa aagccagaat
    16201 aatcagtggc aatacgacaa gctagtactg gcaaccggtg ccagtgcctt tgtcccgcct
    16261 gtgcctgggc gtgagttaat gctgacgtta aatagtcagc aagagtatcg cgcctgtgaa
    16321 acgcaactgc gggatgcccg acgcgtgttg attgttggcg gtggtttgat tggtagcgaa
    16381 ctggcgatgg atttttgtcg tgcaggcaaa gcggtcacgc taatcgacaa cgctgccagt
    16441 attctggcgt cgttaatgcc accggaagta agcagccgct tgcagcatcg gttgacggag
    16501 atgggcgttc atctgctgtt gaaatctcag ttacaggggc tggaaaaaac ggattctggc
    16561 attctggcaa cgctggaccg ccagcgtagc atcgaagtgg atgcggtaat tgccgccacc
    16621 ggactgcgcc cggaaaccgc cctggcacga cgcgccgggc tgacgattaa tcgcggcgtt
    16681 tgcgtcgata gttatctgca aaccagtaat gacgatattt atgcgctggg cgattgcgcg
    16741 gaaatcaacg gtcaggtact gccattcctg cagccgattc aacttagcgc gatggtgctg
    16801 gcaaaaaatc ttctcggcaa taacacgccg ctgaaactac cggcgatgct ggtgaaaatc
    16861 aaaacgccgg aattaccgct gcatctggca ggcgaaaccc agcgtcagga tttacgctgg
    16921 caaattaata ccgaacgcca gggaatggtg gctcgcggtg ttgacgatgc tgaccagctt
    16981 cgcgcctttg tggtcagtga ggatcggatg aaagaggcat ttggattgtt gaaaacattg
    17041 ccgatgtagg tgggctactg tgcctaaaat gtcggatgcg acgctggcgc gtcttatccg
    17101 acctacgggg acgcatgtgt aggccggata aggcgtttac gccgcatccg gcaatggtgt
    17161 ccaaatgcaa cacgttttat ccgttctgga cttcacccgc taaccaacgc gccgcagcaa
    17221 taaccccctg ccccagagac aaaccgccat cacccgccgg taaactctgt ggaaagagca
    17281 atgtgaaatc agcgagataa tgcgccagac gtgcacgcag caaacggtta tgaataaccc
    17341 cgccgctaaa taccagcgta gtgataccac gcatcgtggc ctgctcacgc atcaacgcgg
    17401 caaaaccctg cgccagcgca tcatgaaacg cccacgcgcg ttgattaacc ggtgcctgcc
    17461 agttcagcca ctgctgccag aaagtggcga gatccagttg attgtccacc agcggcattg
    17521 tcaccggatg cgtcactccg tggcacgaag ctgcgagtgc ctccagagca caagccgctt
    17581 caccttcata acttaacgtg gctggcgcac agcccagtgc cgccgccacg gcatcgaaca
    17641 accgcccaca cgatgacgcc agcggcgcgt taattccacg ctcaatggcc cgcgccagca
    17701 cgctccagtt ttgctgttgc acacttgctg tttcagaata attctgccac tccggcacaa
    17761 agcgcaggca ctgcgccagc aggtttcgcc acggctgctt cgccgccaaa tcgccacccg
    17821 gaagcgccac tgcaggcaag ccgcccaggt gctcacattc gcgatagttc acccgcagac
    17881 actcgccgcc ccacaaagcg ccgttctccc ccataccgat accatcgagc gtcaaagcaa
    17941 tgacatcacc gccatccagc ggccactgat gctctgccag acacgccgct gcgtgggcat
    18001 gatgatgcag caccgtttgc gtcggcatat tcatttcgct cgcccactgg ctggagacat
    18061 agcccggatg cacgtcatgc acaacgtatt gcggagtgaa atcgtagatg ttttgcatca
    18121 ggcgtaacgc ttcgcgccac tgcatctgga tgccatcgtc acttaaatcg cccagatgct
    18181 gactcaacac cgcttgttca ccgcgcacca ggcagaaggt gtttttcaga tccgcgccaa
    18241 gacacagcac aggcggaaca tttttaaagc ccggaggcaa aaccagcgca tccggcacat
    18301 acccgcgtga acggcgcagc atttcgccgc tttcgcgcac caccgaatca tccatccgct
    18361 gcacgatgtc gcggttatgt atcaagaatc cgtcggcaat gccctgcaaa tcctccagcg
    18421 cctgttcgtt gctgatagcc ggtggtttac cgctcaggtt gccggaggtc atcaccagcg
    18481 ggcattgcag ttcctgtaac agcaaatgct ggagcgggtt cgcaggcaac attaccccga
    18541 cttcgttaag gtcaggggcg atatcatcac aaagctcagg aacgtatttt ttatccacca
    18601 gcacaatcgg cgcggcgggc gtggtaagca actggcgcgc agcgtctggt aaaccgtcag
    18661 ccactggcaa catgaccgcc agcggtttcg ccgggcgatg tttgcgcgcc cgaagtgtcg
    18721 ccaccgcgtt actgttacgt gcatcgcagg caagatgaaa tccgccaatc cctttgatgg
    18781 cgacaatgtt gcccattttt aactgtgcga tagccgcctg taatgccgcc tcttgttctg
    18841 catgttcacc atgacttacc cattcaagat gtgggccaca ctccgggcag gccaccggct
    18901 gggcgtggaa gcgacgatcg agcgggtcgc ggtactcttt gtcacaagcc ggacacaacg
    18961 gaaacgccgc catcacggta aacgggcggt cgtaaggcat ggcgcgaata atggtgaaac
    19021 gcgggccgca gtgggtacag ttgataaacg gataacgata acgccgttcg cctggggtat
    19081 tcatttcggc aagacaggca gggcaagtag cggcatcggg aacaatttgc gtattcatgg
    19141 tgccgcctgt gctctggcgt atagtgaact cggtgggcag ttgtgaccag atgtacggct
    19201 cacgctcgac gctatcaata cgcgccagcg gcgggcagtg ctgatgcaat tgaacaagaa
    19261 acgtttccgg gtcttccagc agccggactt ctacgccatc gccgtcatta cagacatcgc
    19321 cgtgaagatt taattgctgt gccagctgcc agacaaacgg acgaaaaccg acgccctgca
    19381 ctttgcctcg aatacgcagt tggacaccgc aagatgtgtt ttttgccatt gagttattcc
    19441 cgccatcatg aattgcgtaa cccgccctgc cggacacgac tgcgtcgtat ccggcagtct
    19501 caggtcggcg ataccgccag ctccgtattc tacgaatatt tccgggaatt cctttgatgc
    19561 cagaacagtt ctataagatt tttagaacat cagcgccgta cggcgacgtt tttctgcgct
    19621 cagttgttca agtttattac gatcgacaca aatcagcgca tgggtcgggc aagccgccat
    19681 acacgccggg ccgtcttcgc gatggttgca caggtcgcat ttattggctt cagctttgtc
    19741 agcccgtaca ttcagccccg cgccgctgtt gcggatcacc ggacgtacca ccacttccat
    19801 cgcgccatac gggcaagcca ccacgcaggt tttgcaacca atgcaacgtt cctgcatcac
    19861 atgaacaaac cctttatcac ggctgatagc accattcggg cagacgttag cgcacggtgc
    19921 atcttcacac tgacggcaga ctgtcgccgt ggaaatgttc acacctttaa tgacatggat
    19981 tcgcggtaaa aaggtttccg gggtcagcga tgcacagtcc tgattttcct gatgagaaac
    20041 cacgcacgcc acttcacagg tacggcaacc aatacattta ctcgcgtcag caatgatgaa
    20101 acggttcatc aaattctcca gcaatgacag ttaatgcgcc gatacattca caaatcatgc
    20161 cagtttttaa tttgctgtta tttaaggaaa ttaatttctg taatgcagga aaaaagatgt
    20221 catcgacact agtgacgatg acatgtgatg acaatgttta tcgcgaaagg gcaatgagtg
    20281 agtcgcggcg gatcagtttt ccgctgaagg ttttcggcgg tgagaaatcc ccgccatcga
    20341 gcataaaaat cagccgtcca ataatttcct gaatcatctc tgttaccgga atttttacgc
    20401 tggagagcgc cggaacggtg tagggggcaa ttgcgatatc atcgaatccg ataaccgaca
    20461 cctgctctgg caccgctacg ccgcgctcgt gcaacgcttt gatcgcacct atcgccatat
    20521 cgtcgttact ggcaactaac gcgctaaatt tagccccacg ttcgagcaac gtttctaccc
    20581 cttcggcccc gctggcgggc gtccatttac cgttagcgat aagtttttca ttgagcgcaa
    20641 taccatgctg cgacagcgcg tctttatacc cggcaagacg ttcaacgctg gtgggggaat
    20701 ccatcgagcc ggtaaggaaa gcaatctcct gatgtccggc gtttatcaac tctgccacgg
    20761 cattaaagct ggtctgttta tgatcgcacc agacgctatg gctgctgttt ttgcgcaggc
    20821 ggcgattaag caccattatc ggctgactgt gcgcgtcaat gatgtcatca atctcatcca
    20881 cgcttaaaaa acgcgggtaa atcataatgg cgtcgcagcg caaatccagc agatactgaa
    20941 tcgcctggcg ctcttcttcg gcgctgtgtt taccatctgc caatagcaac tgccgccctt
    21001 tctcttccgc cattcgcgcg gcatgaaaca gtaattcact aaaataaatg ccgtgataaa
    21061 gcgtgttggt cactaccagc cccagcgtct gagtactctt cgccgacaga ttgcgggcca
    21121 gcaaatttgg gcggtaaccg ctctcttcta ccgcctgaaa cacgcgatct ttagtctcct
    21181 ggctgacgta gccattacct gaaagcacgc gggaaacggt cgcttttgaa accccggcgc
    21241 gcttcgccac ttccagcatc gtcgtcatca ttttcatccc tttacacgca atcaacgcag
    21301 tgtactgcac cgtttgccga ttgtccttgc gcaatcggcg ggaaaaatat tcaggtgacc
    21361 ggtttcacaa atataaaaaa tgaacaatta actctcttgc ttatttagtg acaactattc
    21421 atgattttgt gaaaccggtt tcctaattcc gtttcagcat cggcattttt ccgttacgtc
    21481 gactgataac aactacatct accctactga taacaggata aaatccgatg gccaaaaatt
    21541 atgcggcgct ggcacgctcg gtgatagcgg cactgggcgg cgttgataac atctcggcgg
    21601 tcacgcactg tatgacgcgt ttgcgctttg ttatcaaaga tgaccagctt atcgacagcc
    21661 cgacgttaaa aaccatcccc ggcgtgctcg gcgtggtacg tagtgacaac cagtgtcagg
    21721 tgattatcgg caataccgtt tcacaagcct ttcaggaagt cgtcagcctg ctgccgggag
    21781 atatgcagcc cgcacagccc gtgggtaaac ccaaactcac gctgcgtcgc attggtgcag
    21841 ggatcctcga tgcgctgatc ggcaccatgt caccgctgat cccggcgatt atcggcggat
    21901 cgatggtcaa actgctggcg atgatcctcg agatgagcgg cgtgctgaca aaaggatcgc
    21961 cgaccttaac cattctgaat gtgattggtg acggtgcttt cttcttcctg ccgctgatgg
    22021 tcgcggcatc tgccgccatc aaatttaaaa ccaatatgtc gctggcgatt gccatcgcgg
    22081 gtgtgctggt acatccgagt tttattgaac tgatggcgaa agcggcccag ggtgaacatg
    22141 tcgaatttgc cctgattccg gtcaccgcgg tgaaatacac ctacacagtg atcccggcgc
    22201 tggtgatgac ctggtgcctg tcatatatcg aacgctgggt ggatcgcatt acaccggcgg
    22261 tgaccaaaaa cttcctcaag ccaatgctga ttgtgttgat tgccgcaccg ctggcaatcc
    22321 tgctgattgg cccgattggt atctggatcg gtagcgccat ttcggcgctg gtttacacca
    22381 ttcatggtta tctgggctgg ctttcagtcg ccattatggg cgcgctgtgg cctctgctgg
    22441 taatgaccgg gatgcaccgc gtctttacgc caaccatcat tcagaccatt gccgaaaccg
    22501 gcaaagaagg gatggtcatg ccgtcagaga tcggcgctaa cctgtcgctg ggcggttcat
    22561 cactggcggt ggcgtggaaa acgaaaaacc cggaactgcg ccagacggcg ctggctgcgg
    22621 cggcatcagc cattatggcg gggatttccg aaccggcgtt atacggcgtg gcgatccgcc
    22681 tgaaacgtcc gcttatcgcc agtcttatca gcggctttat ttgcggcgcg gttgccggta
    22741 tggcggggct tgccagccac tcaatggcag cgccggggtt atttaccagc gtgcagttct
    22801 tcgatccggc gaatccaatg agcatcgtct gggtgttcgc ggtcatggcg ctggcggtca
    22861 tgctgtcgtt tatcctcaca ctgttgctcg gcttcgagga tattcctgtt gaggaagcga
    22921 ctgccgaggc gcgaaagcat cagagcgtac aaccgaccgt cgccaaagaa gtaagtctta
    22981 attgaggatg aaaatgtcag tatttccaga aggtttttta tggggcggcg cgcttgccgc
    23041 caaccagtct gaaggtgcgt tccgtgaagg tggcaaaggg ctgaccactg tcgatatgat
    23101 cccacacggc gagcatcgaa tggcggtgaa actggggctg gaaaaacgtt ttcagttgcg
    23161 cgatgacgag ttttatccca gccatgaggc gacggatttt tatcatcgtt ataaagaaga
    23221 tatcgccctg atggcagaga tgggattcaa ggttttccgt acctcaattg cctggagccg
    23281 tctctttccg cagggcgatg aaatcacgcc caatcagcag ggcattgctt tttatcgttc
    23341 tgtctttgaa gagtgtaaaa agtacggtat cgaaccgctg gtcacgttgt gccacttcga
    23401 tgtgccgatg catctggtca ccgaatatgg ctcctggcgt aaccgcaagc tggtggagtt
    23461 tttcagccgc tacgcccgga cctgctttga agcatttgat ggtctggtga aatactggct
    23521 taccttcaat gaaatcaaca ttatgttgca tagcccgttc tccggcgcgg gtctggtgtt
    23581 tgaagaaggt gaaaatcagg atcaggtgaa atatcaggcc gcgcatcacc agctggttgc
    23641 cagtgcgcta gccaccaaaa tcgcccatga ggttaacccg caaaatcagg tgggctgtat
    23701 gctggcgggc ggtaacttct acccttacag ttgcaagccg gaagatgtct gggcggcgct
    23761 ggagaaagac cgggaaaacc tgttttttat cgatgtgcag gcgcggggcg cgtatccggc
    23821 ttactctgcc cgcgtattcc gcgaaaaagg ggtaaccatc gacaaagcac cgggcgatga
    23881 tgaaatcctg aaaaacaccg tcgattttgt ctctttcagc tattacgcct cgcgctgcgc
    23941 ctcggcggag atgaacgcca acaatagcag tgcggcgaac gtagtgaaat cgctgcgtaa
    24001 cccgtatctg caagtgagcg actggggctg gggtattgat ccactcggtc tgcgtatcac
    24061 catgaacatg atgtacgacc gttatcagaa gccgctgttt ctggtggaaa acggcctcgg
    24121 cgcaaaagat gaacttgctg ccaatggcga gattaacgat gactatcgca tcagctattt
    24181 acgcgaacat atccgcgcaa tgggcgaagc gattgcagat ggcattccgc tgatgggcta
    24241 caccacatgg ggctgtattg atttagtttc cgcctctacg ggtgaaatga gcaaacgcta
    24301 cggttttgtc tacgtagacc gtgacgacgc aggcaacggc acgctgacgc gcacgcgtaa
    24361 gaaatcgttc tggtggtata aaaaagtaat tgccagtaat ggggaagatt tagagtaagt
    24421 aaccgtgccg gatgcggcgt gaacgcctta tccggcctac atagttcgtg cgaca
//
LOCUS       DAPOAV010000068        23683 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.068, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000068 DAPOAV010000000
VERSION     DAPOAV010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23683
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.068"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..347
                     /gene="tnpA"
                     /locus_tag="RN951_003081"
     CDS             <1..347
                     /gene="tnpA"
                     /locus_tag="RN951_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001407245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HDX2528049.1"
                     /translation="GPDHVHLLINYPPKLAISSLVNSLKGVSSRLLRRDRPDIAVRYY
                     DKGVLWSPGYFVSSCILTYQLDLITTISVPNRISNVISIPLIIPSTSCNFPTLELHIV
                     QTPDAKKSHVHF"
     gene            complement(504..1301)
                     /locus_tag="RN951_003082"
     CDS             complement(504..1301)
                     /locus_tag="RN951_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX2528050.1"
                     /translation="MLAKDKTNLKIEEIRMHKHHEIHRVKPLMPALCRIRQGKKVINW
                     ETHSLTVDNNQIILFPCGYEFYIANYPEAGLYLAEMLYYPIDLIEKFQKFYAITDQIR
                     NTTGFCLPQNPELIYCWEQLKTSISRGFSTQIQEHLAMGVLLSLGAHHVNCLLLSDSK
                     QSLISRCYNLMLSEPGTKWTANKVARYLYISVSTLHRRLASEGVSFQSILDDVRLNNA
                     LSAIQTTVKPISEIARENGYKCPSRFTERFHNRFKITPRELRKASRE"
     gene            complement(1311..1862)
                     /gene="ybcL"
                     /locus_tag="RN951_003083"
     CDS             complement(1311..1862)
                     /gene="ybcL"
                     /locus_tag="RN951_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Raf kinase inhibitor-like protein YbcL"
                     /protein_id="HDX2528051.1"
                     /translation="MKKLIVSSVLAFITFSAQAAAFQVTSNEIKTGEQLTTSHVFSGF
                     GCEGGNTSPSLTWSGAPEGTKSFAVTVYDPDAPTGSGWWHWTVANIPATVTYLPADAG
                     RRDGTKLPTGAVQGRNDFGYAGFGGACPPKGDKPHHYQFKVWALKTDKIPVDSNSSGA
                     LVGYMLNANKIATAEITPVYEIK"
     gene            complement(2031..2363)
                     /gene="emrE"
                     /locus_tag="RN951_003084"
     CDS             complement(2031..2363)
                     /gene="emrE"
                     /locus_tag="RN951_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMR family multidrug efflux protein EmrE"
                     /protein_id="HDX2528052.1"
                     /translation="MNPYIYLGGAILAEVIGTTLMKFSEGFTRLWPSVGTIICYCASF
                     WLLAQTLAYIPTGIAYAIWSGVGIVLISLLSWGFFGQRLDLPAIIGMMLICAGVLVIN
                     LLSRSAPH"
     gene            complement(2707..3021)
                     /gene="fliE"
                     /locus_tag="RN951_003085"
     CDS             complement(2707..3021)
                     /gene="fliE"
                     /locus_tag="RN951_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HDX2528053.1"
                     /translation="MSAIQGIEGVISQLQATAMSARAQDSLPQPTISFAGQLHAALDR
                     ISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSM
                     QV"
     gene            3236..4894
                     /gene="fliF"
                     /locus_tag="RN951_003086"
     CDS             3236..4894
                     /gene="fliF"
                     /locus_tag="RN951_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HDX2528054.1"
                     /translation="MNATAAQTKSLEWLNRLRANPKIPLIVAGSAAVAVMVALILWAK
                     APDYRTLFSNLSDQDGGAIVSQLTQMNIPYRFSEASGAIEVPADKVHELRLRLAQQGL
                     PKGGAVGFELLDQEKFGISQFSEQVNYQRALEGELSRTIETIGPVKGARVHLAMPKPS
                     LFVREQKSPSASVTVNLLPGRALDEGQISAIVHLVSSAVAGLPPGNVTLVDQGGHLLT
                     QSNTSGRDLNDAQLKYASDVEGRIQRRIEAILSPIVGNGNIHAQVTAQLDFASKEQTE
                     EQYRPNGDESHAALRSRQLNESEQSGSGYPGGVPGALSNQPAPANNAPISTPPANQNN
                     RQQQASTTSNSGPRSTQRNETSNYEVDRTIRHTKMNVGDVQRLSVAVVVNYKTLPDGK
                     PLPLSNEQMKQIEDLTREAMGFSEKRGDSLNVVNSPFNSSDEGGGELPFWQQQAFIDQ
                     LLAAGRWLLVLLVAWLLWRKAVRPQLTRRAEAMKAVQQQAQAREEVEDAVEVRLSKDE
                     QLQQRRANQRLGAEVMSQRIREMSDNDPRVVALVIRQWINNDHE"
     gene            4887..5882
                     /gene="fliG"
                     /locus_tag="RN951_003087"
     CDS             4887..5882
                     /gene="fliG"
                     /locus_tag="RN951_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HDX2528055.1"
                     /translation="MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANV
                     TQISNKQLTDVLAEFEQEAEQFAALNINANDYLRSVLVKALGEERAASLLEDILETRD
                     TASGIETLNFMEPQSAADLIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLR
                     IATFGGVQPAALAELTEVLNGLLDGQNLKRSKMGGVRTAAEIINLMKTQQEEAVITAV
                     REFDGELAQKIIDEMFLFENLVDVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLR
                     NMSQRAADILRDDLANRGPVRLSQVENEQKAILLIVRRLAETGEMVIGSGEDTYV"
     gene            5875..6561
                     /gene="fliH"
                     /locus_tag="RN951_003088"
     CDS             5875..6561
                     /gene="fliH"
                     /locus_tag="RN951_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707825.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HDX2528056.1"
                     /translation="MSDNLPWKTWMPDDLAPPPAEFVPIVEPEETIIEEAEPSLEQQL
                     AQLQMQAHEQGYQAGIAEGRQQGHEQGYQEGLAQGLEQGLAEAKAQQAPIHARMQQLV
                     SEFQTTLDALDSVIASRLMQMALEAARQVIGQTPTVDNSALIKQIQLLLQQEPLFSGK
                     PQLRVHPDDLQRVDDMLGATLSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQE
                     LCRLAAPGVV"
     gene            6561..7934
                     /gene="fliI"
                     /locus_tag="RN951_003089"
     CDS             6561..7934
                     /gene="fliI"
                     /locus_tag="RN951_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellum-specific ATP synthase FliI"
                     /protein_id="HDX2528057.1"
                     /translation="MTTRLTRWLTTLDNFEAKMAQLPAVRRYGRLTRATGLVLEATGL
                     QLPLGATCVIERQNGSETHEVESEVVGFNGQRLFLMPLEEVEGVLPGARVYAKNISAE
                     GLQSGKQLPLGPALLGRVLDGSGKPLDGLPSPDTTETGALITPPFNPLQRTPIEHVLD
                     TGVRPINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTRADVIVVGLIGERGREVKD
                     FIENILGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTR
                     YAMAQREIALAIGEPPATKGYPPSVFAKLPALVERAGNGISGGGSITAFYTVLTEGDD
                     QQDPIADSARAILDGHIVLSRRLAEAGHYPAIDIEASISRAMTALISEQHYARVRTFK
                     QLLSSFQRNRDLVSVGAYAKGSDPMLDKAIALWPQLEGYLQQGIFERADWEASLQGLE
                     RIFPTVS"
     gene            7953..8396
                     /gene="fliJ"
                     /locus_tag="RN951_003090"
     CDS             7953..8396
                     /gene="fliJ"
                     /locus_tag="RN951_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis chaperone FliJ"
                     /protein_id="HDX2528058.1"
                     /translation="MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLID
                     YQNEYRNNLNSDMSAGMTSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWR
                     EKKQRLQAWQTLQERQSTAALLAENRLDQKKMDEFAQRAAMRKPE"
     gene            8393..9520
                     /gene="fliK"
                     /locus_tag="RN951_003091"
     CDS             8393..9520
                     /gene="fliK"
                     /locus_tag="RN951_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook length control protein FliK"
                     /protein_id="HDX2528059.1"
                     /translation="MIRLAPLITADVDTTTLSGGKASDAAQDFLALLSEALTGEATTD
                     KATPQLLVATDKPTTKGEPLVSDIVSDAQQADLLIPVDETPPVINDEQSTSTPLNTAQ
                     TITLAAAADNNTAKDEKADDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLPTEKP
                     TLFTKLTSAQLTTAQPDDAPGTPAQPLTPLIAEAQSKAEIISTPSPVTAAASPLITPH
                     QTQPLPTVAAPVLSAPLGSHEWQQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLK
                     VDDNQAQIQMVSPHQHVRAALEAALPVLRTQLAESGIQLGQSNISGESFSGQQQAASQ
                     QQQSQRTVNHEPLAGEEDDTLPVPVSLQGRVTGNSGVDIFA"
     gene            9625..10089
                     /gene="fliL"
                     /locus_tag="RN951_003092"
     CDS             9625..10089
                     /gene="fliL"
                     /locus_tag="RN951_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated protein FliL"
                     /protein_id="HDX2528060.1"
                     /translation="MTDYAISKKSKRSLWIPILVFITLAACASAGYSYWHSHQVAADD
                     KAQQRVVPSPVFYALDTFTVNLGDADRVLYIGITLRLKDEATRSRLSEYLPEVRSRLL
                     LLFSRQDAAVLATEEGKKNLITEIKTTLSTPLVAGQPKQDVTDVLYTAFILR"
     gene            10094..11098
                     /gene="fliM"
                     /locus_tag="RN951_003093"
     CDS             10094..11098
                     /gene="fliM"
                     /locus_tag="RN951_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliM"
                     /protein_id="HDX2528061.1"
                     /translation="MGDSILSQAEIDALLNGDSEVKDEPTASVSGESDIRPYDPNTQR
                     RVVRERLQALEIINERFARHFRMGLFNLLRRSPDITVGAIRIQPYHEFARNLPVPTNL
                     NLIHLKPLRGTGLVVFSPSLVFIAVDNLFGGDGRFPTKVEGREFTHTEQRVINRMLKL
                     ALEGYSDAWKAINPLEVEYVRSEMQVKFTNITTSPNDIVVNTPFHVEIGNLTGEFNIC
                     LPFSMIEPLRELLVNPPLENSRNEDQNWRDNLVRQVQHSQLELVANFADISLRLSQIL
                     KLKPGDVLPIEKPDRIIAHVDGVPVLTSQYGTLNGQYALRIEHLINPILNSLNEEQPK
                     "
     gene            11095..11508
                     /gene="fliN"
                     /locus_tag="RN951_003094"
     CDS             11095..11508
                     /gene="fliN"
                     /locus_tag="RN951_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliN"
                     /protein_id="HDX2528062.1"
                     /translation="MSDMNNPADDNNGAMDDLWAEALSEQKSTSSKSAADAVFQQFGG
                     GDVSGTLQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILIN
                     GYLIAQGEVVVVADKYGVRITDIITPSERMRRLSR"
     gene            11511..11876
                     /gene="fliO"
                     /locus_tag="RN951_003095"
     CDS             11511..11876
                     /gene="fliO"
                     /locus_tag="RN951_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FliO"
                     /protein_id="HDX2528063.1"
                     /translation="MNNHATVQSSTPVSAAPLLQVSGALIAIIALILAAAWLVKRLGF
                     APKRTGVNGLKISASASLGARERVVVVDVEDARLVLGVTAGQINLLHKLPPSAPTEEI
                     PQTDFQSVMKNLLKRSGRS"
     gene            11876..12613
                     /gene="fliP"
                     /locus_tag="RN951_003096"
     CDS             11876..12613
                     /gene="fliP"
                     /locus_tag="RN951_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310714.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HDX2528064.1"
                     /translation="MRRLLSVAPVLLWLVTPLAFAQLPGITSQPLPGGGQSWSLPVQT
                     LVFITSLTFIPAILLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMS
                     PVIDKIYVDAYQPFSEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQ
                     GPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIA
                     LPFKLMLFVLVDGWQLLVGSLAQSFYS"
     gene            12623..12892
                     /gene="fliQ"
                     /locus_tag="RN951_003097"
     CDS             12623..12892
                     /gene="fliQ"
                     /locus_tag="RN951_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013365797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HDX2528065.1"
                     /translation="MTPESVMMMGTEAMKVALALAAPLLLVALVTGLIISILQAATQI
                     NEMTLSFIPKIIAVFIAIIIAGPWMLNLLLDYVRTLFTNLPYIIG"
     gene            12900..13685
                     /gene="fliR"
                     /locus_tag="RN951_003098"
     CDS             12900..13685
                     /gene="fliR"
                     /locus_tag="RN951_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FliR"
                     /protein_id="HDX2528066.1"
                     /translation="MLQVTSEQWLSWLSLYFWPLLRVLALISTAPIVSERSVPKRVKL
                     GLAMMITFAIAPSLPANDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEII
                     GLQMGLSFATFVDPASHLNMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIG
                     GEPLNSNAFLALTKAGSLIFLNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGF
                     PLTLTVGISLMAALMPLIASFCEHLFSEIFNLLADIISELPLI"
     gene            13975..14589
                     /gene="rcsA"
                     /locus_tag="RN951_003099"
     CDS             13975..14589
                     /gene="rcsA"
                     /locus_tag="RN951_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RcsA"
                     /protein_id="HDX2528067.1"
                     /translation="MSMIIMDLCSYTRLGLTGYLLSRGVKKREINDIETVDDLAIACD
                     SQRPSVVFINEDCFIHDASNSQHIINQHPNTLFIVFMAIANVHFDEYLLVRKNLLISS
                     KSIKPESLDDILGDILKKETTITSFLNMPTLSLSRTESSMLRMWMAGQGTIQISDQMN
                     IKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR"
     gene            complement(14633..14821)
                     /gene="dsrB"
                     /locus_tag="RN951_003100"
     CDS             complement(14633..14821)
                     /gene="dsrB"
                     /locus_tag="RN951_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DsrB"
                     /protein_id="HDX2528068.1"
                     /translation="MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVSLEDYPLGI
                     WFFNEAGHQDGIFVEKAE"
     gene            14984..15211
                     /gene="yodD"
                     /locus_tag="RN951_003101"
     CDS             14984..15211
                     /gene="yodD"
                     /locus_tag="RN951_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416463.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid resistance protein YodD"
                     /protein_id="HDX2528069.1"
                     /translation="MKTAKEYSDTAKREVSVDVDALLAAINEISESEVHRSQNDSEHV
                     SVDGREYHTWRELADAFELDIHDFSVSEVNR"
     gene            15509..16323
                     /locus_tag="RN951_003102"
                     /pseudo
     CDS             15509..16323
                     /locus_tag="RN951_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310720.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-3-phosphoglycerate phosphatase-related
                     protein"
     gene            complement(16320..18014)
                     /gene="yedQ"
                     /locus_tag="RN951_003103"
                     /pseudo
     CDS             complement(16320..18014)
                     /gene="yedQ"
                     /locus_tag="RN951_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310721.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis regulator YedQ"
     gene            complement(18252..18434)
                     /locus_tag="RN951_003104"
     CDS             complement(18252..18434)
                     /locus_tag="RN951_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2158 domain-containing protein"
                     /protein_id="HDX2528070.1"
                     /translation="MSFMVSEEVTVKEGGPRMIVTGYSSGMVECRWYDGYGVKREAFH
                     ETELVPGEGSRSAEEV"
     gene            complement(18513..19430)
                     /locus_tag="RN951_003105"
     CDS             complement(18513..19430)
                     /locus_tag="RN951_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF808 domain-containing protein"
                     /protein_id="HDX2528071.1"
                     /translation="MLLAGSSLLTLLDDIATLLDDISVMGKLAAKKTAGVLGDDLSLN
                     AQQVSGVRANRELPVVWGVAKGSLINKVILVPLALIISAFIPWAITPLLMIGGAFLCF
                     EGVEKVLHMLEARKHKEDPAQSQQRLEKLAAQDPLKFEKDKIKGAIRTDFILSAEIVA
                     ITLGIVAEAPLLNQVLVLSGIALVVTVGVYGLVGVIVKIDDLGYWLAEKSSALMQALG
                     KGLLIIAPWLMKALSIVGTLAMFLVGGGIVVHGIAPLHHAIEHFAGQQSAVVAMILPT
                     VLNLILGFIIGGIVVLGVKAVAKIRGQAH"
     gene            19603..20523
                     /gene="yedA"
                     /locus_tag="RN951_003106"
     CDS             19603..20523
                     /gene="yedA"
                     /locus_tag="RN951_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="drug/metabolite exporter YedA"
                     /protein_id="HDX2528072.1"
                     /translation="MRFRQLLPLFGALFALYIIWGSTYFVIRIGVESWPPLMMAGVRF
                     LAAGILLLAFLLLRGHKLPPLRPLLNAALIGLLLLAVGNGMVTVAEHQNVPSGIAAVV
                     VATVPLFTLCFSRLFGIKTRKLEWVGIAIGLAGIIMLNSGGNLSGNPWGAILILIGSI
                     SWAFGSVYGSRITLPVGMMAGAIEMLAAGVVLMIASMIAGEKLTALPSLSGFLAVGYL
                     ALFGSIIAINAYMYLIRNVSPALATSYAYVNPVVAVLLGTGLGGETLSKIEWLALGVI
                     VFAVVLVTLGKYLFPAKPVVAPVIQDASSE"
     gene            complement(20512..20982)
                     /gene="vsr"
                     /locus_tag="RN951_003107"
     CDS             complement(20512..20982)
                     /gene="vsr"
                     /locus_tag="RN951_003107"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VSPR family DNA mismatch endonuclease"
                     /protein_id="HDX2528073.1"
                     /translation="MADVHDKATRSKNMRAIATRDTAIEKRLASLLTGQGLAFRVQDA
                     SLPGRPDFVVDEYRCVIFTHGCFWHHHHCYLFKVPATRTEFWLEKISKNVERDRRDIS
                     RLQELGWRVLIVWECALRGREKLTDEALTERLEEWICGEGASAQIDTQGIHLLA"
     gene            complement(20963..22381)
                     /gene="dcm"
                     /locus_tag="RN951_003108"
     CDS             complement(20963..22381)
                     /gene="dcm"
                     /locus_tag="RN951_003108"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-cytosine methyltransferase"
                     /protein_id="HDX2528074.1"
                     /translation="MQENISVTDSYSTGNAAQAMLEKLLQIYDVKTLVAQLNGVGENH
                     WSAAILKRALANDSAWHRLSEKEFAHLQTLLPKPPAHHPHYAFRFIDLFAGIGGIRRG
                     FESIGGQCVFTSEWNKHAVRTYKANHYCDPATHHFNEDIRDITLSHKEGVSDEAAAEH
                     IRQHIPEHDVLLAGFPCQPFSLAGVSKKNSLGRAHGFACDTQGTLFFDVVRIIDARRP
                     AMFVLENVKNLKSHDQGKTFRIIMQTLDELGYDVADAEDNGPDDPKIIDGKHFLPQHR
                     ERIVLVGFRRDLNLKADFTLRDISECFPAQRVTLAQLLDPMVEAKYILTPVLWKYLYR
                     YAKKHQARGNGFGYGMVYPNNPQSVTRTLSARYYKDGAEILIDRGWDMAKGEKDFDDP
                     QNQQHRPRRLTPRECARLMGFEAPGEAKFRIPVSDTQAYRQFGNSVVVPVFAAVAKLL
                     EPKIKQAVALRQQEAQHGRRSR"
     gene            complement(22448..23143)
                     /locus_tag="RN951_003109"
     CDS             complement(22448..23143)
                     /locus_tag="RN951_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HDX2528075.1"
                     /translation="MDLQHWQAQFENWLKNHHQHQDAAHDVCHFRRVWATAQKLAADD
                     DVDMLVILTACYFHDIVSLAKNHPQRQRSSILAAEETRRLLREEFEQFPAEKIEAVCH
                     AIAAHSFSAQIAPLTTEAKIVQDADRLEALGAIGLARVFAVSGALGVALFDGEDPFAQ
                     HRPLDDKRYALDHFQTKLLKLPQTMQTARGKQLAQHNAHFLVEFMAKLSAELAGENEG
                     VDHKVIDAFSSAG"
     gene            complement(23183..23548)
                     /locus_tag="RN951_003110"
     CDS             complement(23183..23548)
                     /locus_tag="RN951_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDX2528076.1"
                     /translation="MEKCDFYHIIVLSLSFPGYLKMEYGSTKMEERLSRSPGGKLALW
                     AFYTWCGYFVWAMARYIWVMSRIPDAPVSGFESDLGSTAGKWLGALVGFLFMALVGAL
                     LGSIAWYTRPRPARSRRYE"
BASE COUNT         5863 a         6163 c         5937 g         5720 t
ORIGIN      
        1 gcggaccaga tcacgtccat ttgttaatta actatcctcc caaactggcg atatccagtc
       61 tggtaaacag cctcaaaggc gtatcgagta ggttactgcg acgagatcga ccagatattg
      121 cagtcaggta ttacgacaaa ggcgttttgt ggagtcctgg ctattttgtc agtagctgca
      181 tcttaacgta tcaactagat ttaataacaa cgatatccgt acctaaccgg atatctaatg
      241 tcataagcat ccctttaatt atcccctcaa cctcttgtaa ctttcccact cttgagctcc
      301 acatagtcca aacgccggat gcaaaaaaat cacacgtgca tttctgaaat tgtgatggag
      361 gaagatagta tcaattatat gtgcttagaa acgtccccga ttagcgcaga agtcaccgga
      421 ttgttcagac tccaataggt tgagtatgcc gtatttattt tccaaaataa aaatcgatgc
      481 tgttgctcct tcataaaata cttttactct ctggacgctt ttcttagctc tcttggtgtt
      541 atcttaaaac gattatggaa cctttcagta aaacgagaag gacacttgta accattttcc
      601 ctggcaatct cgctgatggg ttttactgtc gtttgtatag cagacaacgc attatttaac
      661 ctcacgtcgt ccaatatact ttgaaaactt actccctcgc ttgccagacg gcgatgcaat
      721 gtggaaacag aaatgtagag atatctcgct accttgtttg ctgtccattt tgttccaggt
      781 tcggatagca ttaggttata acaacgactt attaatgatt gtttactatc tgataaaagt
      841 aaacaattaa catgatgtgc tcctaatgaa agtagaacgc ccattgctaa gtgttcctga
      901 atttgcgttg agaagcctcg ggaaatagat gtttttagtt gctcccaaca atatattaac
      961 tcggggttct gaggtaagca gaaacctgtc gtgttacgaa tttgatcagt tatcgcataa
     1021 aatttttgaa acttttcaat tagatcaatg ggataataaa gcatttctgc aagataaaga
     1081 cctgcttctg gataattcgc aatataaaat tcatatccac agggaaataa tattatctga
     1141 ttattatcaa cagttagact atgcgtctcc caattgataa ctttttttcc ctgacggata
     1201 cgacataaag ctggcataag aggcttaacc ctgtgaatct catgatgttt atgcatccgt
     1261 atttcttcaa tctttaggtt agtcttatct tttgccagca tactcttacc ctactttatc
     1321 tcataaactg gtgttatctc agcggttgca attttattgg cattaagcat ataaccaact
     1381 aacgctccgc tggaattaga atccacagga attttatcag tttttagagc ccatacttta
     1441 aactggtaat gatggggttt atctcctttg ggaggacatg ctccaccaaa tcctgcataa
     1501 ccaaaatcat ttcggccttg aacagcacca gtcggaagtt ttgtaccatc acgtcttcct
     1561 gcatcagcgg gcaaatatgt tacagttgct ggaatattag caacagtcca gtgccaccat
     1621 ccactgcctg taggagcatc tggatcatac acagttacgg caaagctttt ggtgccttca
     1681 ggagcaccag accaggttaa tgagggcgat gtattaccac cttcacaccc aaatccagaa
     1741 aatacatgag acgttgtaag ttgctctcct gtttttattt cattactagt gacctgaaat
     1801 gctgcggcct gcgcagaaaa tgttatgaat gccaatacac ttgaaacgat aagttttttc
     1861 ataaaaacct cattgttgtg acctatcgtt attttatttg atgtgccttg atctcattat
     1921 gcataaaggc gcaatgatcg cgcaaatgca atcataatta taaaggtgcc ccgaacatta
     1981 gccataatat gcacaaatca gattcctgtt atctcaagga taattatttt ttaatgcggt
     2041 gcacttcgtg acaacaagtt aatgactaac acaccggcac aaatcaacat catgcctatg
     2101 atagctggca ggtccagtcg ttgaccaaaa aatccccagg aaagcaaact aatcagaacg
     2161 ataccgacgc ctgaccagat agcataagca atccctgtag gtatataagc cagcgtctga
     2221 gctaataacc agaatgatgc acaatagcaa ataattgtgc caacagaggg ccataaccgt
     2281 gtaaacccct ctgaaaactt cattaaggtt gtaccaatga cctctgcaag tattgcgcca
     2341 ccaagataaa tataagggtt catagcatat tctttcctgt tcatactgga gagaattgta
     2401 ctacagtttg aacacaactc accgttttca tcctagtgta tgtgtatcca gggggctctg
     2461 gcgtggcaag agataaaggc aggaacaata atgatcagaa ggaaccccag gctaacgaat
     2521 gagttcactc ttcctgggag caaagcgaag acaaaacatg ttatcgcgtt tacggatcgt
     2581 ggatggcaga aaactttcag gatcaggtat ccattttaaa ccagaaattg agtgagtttg
     2641 ccccatccat gccccacgct gtgggatcgg atataataaa caagcatagt caacaggtta
     2701 caaaacctac acctgcatgg acatcacttc ctgatacgcc gccaccagct tattacgcac
     2761 ctgaatcccc atttgcatag aaactgaggc tttttgcata tcggtcatca catcgtttaa
     2821 cgccacgccg ggttcaccga gggtgaattt ttctgcctgc gtgcgggcag ctgtttgtgt
     2881 atcgctaatg cgatcgagcg cggcgtgcag ctgcccggca aaactaatgg tcggttgcgg
     2941 cagtgaatcc tgcgcacgcg cactcatcgc cgtagcctgt aactggctga taaccccttc
     3001 aatcccctgt atcgctgaca ttttcgtctc ctggataatt tctggtagca aagcctacca
     3061 gtaagtcaat aagacaaagg cgctaaatag caacaaaaaa acgggtttat tggcggatag
     3121 aaaaaaacga aagcacaaat aatggcagcg tcaatttttc gagtttgctg acccgggagt
     3181 gagtcttgtt ccactttgcc aataacgccg tccataatca gccacgaggt gcgcgatgaa
     3241 tgcgactgca gcccagacaa aatctcttga gtggcttaat cgcctgcgtg cgaatccgaa
     3301 aattccattg attgttgccg gttccgcggc agtggcggtc atggtcgcac tgatcctgtg
     3361 ggcgaaagcc cccgactacc gcacattatt cagcaatctt tccgatcagg atggtggcgc
     3421 aattgtcagc caactgacgc aaatgaatat tccttaccgc ttcagcgaag ccagcggcgc
     3481 tattgaagtt ccggcagata aagttcacga gctgcgtctg cgcctggcgc aacaaggttt
     3541 gcccaaaggc ggcgcggtcg gtttcgaact actcgatcag gaaaagtttg gtatcagcca
     3601 gttcagcgaa caggtgaatt atcagcgggc gttggaaggc gagctttctc gtaccatcga
     3661 aactatcggc ccggtaaaag gggcgcgcgt acatctggca atgccgaaac cgtctttatt
     3721 cgtccgtgaa caaaaatccc cttctgcatc ggtgacggta aatctgttac ccggccgcgc
     3781 actcgatgaa gggcaaatta gcgccattgt gcatctggtt tccagcgccg ttgctggtct
     3841 gccgccggga aacgtcacgc tggtggatca gggcggacat ctgttaaccc agtccaatac
     3901 cagcgggcgc gatcttaatg atgctcagtt gaaatatgcc agcgatgtcg aaggccgtat
     3961 tcagcggcgt attgaagcaa tcctgtcgcc tattgttggt aacggtaata ttcacgccca
     4021 ggtcacggcg cagctggact tcgccagtaa agaacaaacg gaagaacagt atcgccctaa
     4081 cggtgatgaa tctcatgcgg cgcttcgttc acgccagctt aatgagagcg agcaaagcgg
     4141 ttccggttat ccgggcggcg taccgggggc gttgtcgaat caaccggcac ctgcgaataa
     4201 cgcgccaatc agcacgcctc cggcaaatca aaataaccgc cagcagcagg cgagcaccac
     4261 cagcaatagc gggccgcgta gcacacagcg gaatgaaacc agtaactacg aagtcgatcg
     4321 caccattcgt cataccaaaa tgaacgtggg cgatgtgcaa cgtctgtcag tcgcggtagt
     4381 ggtgaattac aaaaccttgc cagacggtaa accattgcct ctcagcaacg aacagatgaa
     4441 gcaaattgaa gatctgaccc gcgaggcgat gggcttttct gaaaaacgcg gcgactcgct
     4501 caatgtcgtt aactcgccgt tcaatagcag tgacgaaggc ggcggagaac tgccgttctg
     4561 gcaacagcaa gcgtttatcg atcagttgct ggctgccggt cgctggttgc tggtactgct
     4621 ggtggcgtgg ctgctgtggc ggaaagcggt acgcccgcag ttaacacgtc gcgccgaggc
     4681 gatgaaagct gtacagcaac aggcgcaggc ccgtgaggaa gtggaagatg cggtggaagt
     4741 ccgcctgagc aaagacgaac aactccaaca acgacgcgct aaccaacgtc tgggggcaga
     4801 agtcatgagc cagcgtatcc gtgaaatgtc tgataacgat ccgcgcgtgg tggcgctggt
     4861 cattcgccag tggataaata acgatcatga gtaacctgac aggcaccgat aaaagcgtca
     4921 tcctgctgat gaccattggc gaagaccggg cggcagaggt gttcaagcac ctctcccagc
     4981 gcgaagtgca aaccctgagc gctgcaatgg cgaacgtcac gcagatctcc aacaagcagc
     5041 taaccgatgt gctggcggag tttgagcaag aagctgaaca gtttgccgca ctgaatatca
     5101 acgccaacga ttatctgcgt tcggtattgg tcaaagctct gggtgaggaa cgtgccgcca
     5161 gcctgctgga agatattctc gaaactcgcg ataccgccag cggtattgaa acgctcaact
     5221 ttatggagcc gcagagtgcc gccgatctga ttcgcgatga gcatccgcaa attatcgcca
     5281 ccattctggt gcatctgaag cgcgcccagg ccgccgatat tctggcgttg ttcgatgaac
     5341 gtctgcgcca cgacgtgatg ttgcgtatcg ccacctttgg cggcgtgcag ccagccgcgc
     5401 tggcggaact gaccgaagta ctgaatggct tgctcgacgg tcagaatctc aagcgcagca
     5461 aaatgggcgg cgtgagaacg gcagccgaaa ttatcaacct gatgaaaact cagcaggaag
     5521 aagccgttat taccgccgtg cgtgaattcg acggcgaact ggcgcaaaaa attatcgacg
     5581 agatgttcct gttcgagaat ctggtggatg tcgacgatcg cagcattcag cgtctgttgc
     5641 aggaagtgga ttccgaatcg ttgctgatcg cgctgaaagg ggccgagcag ccactgcgcg
     5701 agaaattcct gcgcaatatg tcgcaacgtg ccgccgatat tctgcgcgac gatctcgcca
     5761 accgtggtcc ggtgcgtctg tcgcaggtgg aaaacgaaca gaaagcgatt ctgctgattg
     5821 tgcgccgtct tgccgaaacc ggcgagatgg tgattggcag cggcgaggat acctatgtct
     5881 gataatctgc cgtggaaaac ctggatgccg gacgatcttg cgccaccacc ggcagagttt
     5941 gtgccaatag tcgaaccgga agaaaccatc attgaagagg ccgaacccag ccttgagcag
     6001 caactggcgc aactgcaaat gcaggcccac gagcagggtt atcaggcggg gattgccgaa
     6061 ggtcgccagc aaggtcacga acagggctat caggaaggac tggcccaggg gctggaacaa
     6121 ggtctggcag aggcgaaggc tcaacaagcg ccaattcatg cccggatgca gcaactggtc
     6181 agcgaatttc aaactaccct tgatgcgctt gatagtgtga ttgcttcgcg cctgatgcag
     6241 atggcgctgg aggcagcacg tcaggtgatc ggtcagacgc caacggtgga taactcggca
     6301 ctgatcaaac agatccaact gttgttgcag caagaaccgt tgttcagcgg caaaccgcag
     6361 ctgcgcgtgc acccggatga tctgcaacgt gtggatgata tgctcggcgc aactttaagt
     6421 ttgcatggct ggcgcttgcg gggcgatccc accctccatc ctggcggctg taaagtctcc
     6481 gccgatgaag gcgatctcga cgccagtgtc gccactcgct ggcaagaact ctgccgtctg
     6541 gcagcaccag gagtggtgta atgaccacgc gcctgactcg ctggctaacc acgctggata
     6601 acttcgaagc taaaatggcg cagttgcctg cggtacgtcg ctacgggcga ttaactcgcg
     6661 ctaccgggct ggtgctggaa gccaccggat tacaattgcc gctcggcgca acctgtgtga
     6721 ttgagcgcca gaacggcagc gaaacgcacg aagtagaaag cgaagtcgtt ggctttaacg
     6781 gtcaacggct gtttttaatg ccgctggagg aagtggaagg tgtcctgccc ggcgcgcgtg
     6841 tttatgccaa aaacatttcg gctgaagggc tgcaaagcgg caagcagctg ccgctcggtc
     6901 cggcgttatt aggtcgcgtt ctggacggca gcggtaaacc gctcgatggc ctcccctccc
     6961 ccgatacgac ggaaaccggt gcgctgatta ccccgccatt taacccattg caacgtacac
     7021 cgattgaaca tgtgctggac accggcgtgc gcccaatcaa tgccctgctt accgtcgggc
     7081 gcgggcagcg tatggggctg tttgccgggt ccggcgttgg taaaagtgtg ctgctgggga
     7141 tgatggcccg ttacacccgc gccgatgtca ttgtcgtggg tttgattggt gaacgcggac
     7201 gcgaagtaaa agattttatt gagaatatcc tcggtgccga agggcgtgca cgctccgtgg
     7261 tgattgccgc tccggcggat gtttctccgc ttctgcgaat gcaaggtgcc gcctatgcca
     7321 cgcgaattgc cgaagatttt cgcgatcgtg gtcagcatgt attgctgatt atggactccc
     7381 tcacccgcta cgcgatggcc cagcgtgaga ttgcgctggc gattggcgaa ccacctgcca
     7441 ctaaaggtta tccaccgtcg gtgtttgcca aattaccggc actggtcgag cgtgccggaa
     7501 atggcattag cggcggcggc tcgattaccg cgttttatac cgtgctcacc gaaggcgatg
     7561 accagcagga ccccattgcc gactccgcgc gggccatcct cgacggccac attgtgctgt
     7621 ctcgccgact ggcggaagcc gggcactatc cggctatcga tattgaagcg tcgatcagtc
     7681 gcgcaatgac ggcgttgatc agtgagcaac attacgcgcg agtgcgcacc ttcaaacagc
     7741 tgttgtcgag ttttcagcgt aaccgcgatc tggttagcgt cggcgcgtat gccaaaggca
     7801 gcgatccgat gctcgataaa gccatcgccc tgtggccgca gctggagggc tatttgcaac
     7861 aaggcatttt tgaacgcgcg gactgggaag cgtctctcca ggggctggag cgtattttcc
     7921 cgacagtgtc ataacccagg agataacggc agatggcgga acatggtgcg ctggcgaccc
     7981 tgaaagatct ggcagaaaaa gaggtagagg atgccgctcg cctgctgggt gaaatgcgtc
     8041 gcggatgtca gcaggcggaa gaacagctca aaatgctgat cgattatcag aatgaatatc
     8101 gcaataacct caatagcgat atgagtgccg ggatgaccag caaccgctgg atcaactatc
     8161 agcagtttat ccagacgctg gaaaaagcca ttactcagca tcgccagcaa cttaatcagt
     8221 ggacgcagaa agttgacatt gccctgaaca gctggcgaga aaagaaacaa cgtttgcagg
     8281 cctggcagac actgcaggaa cggcaatcca cggcggcact gcttgcagaa aaccgcctcg
     8341 atcagaaaaa gatggatgag ttcgcccagc gcgccgccat gaggaaacct gaatgattcg
     8401 cttagcgccc ttgattaccg ccgacgttga caccaccaca ttgtctggcg gcaaagccag
     8461 cgatgctgca caagattttc tcgcgttgtt gagcgaagca ttaacaggcg aggcaacaac
     8521 cgacaaagcg actccccagt tgctggtggc aacagataag cccacgacaa aaggcgagcc
     8581 gctggtcagc gatattgttt ccgacgcgca acaagcggat ttactgatcc ctgtggatga
     8641 aacaccgcct gtcatcaacg acgaacaatc cacatcaaca ccgttaaaca ccgctcagac
     8701 gataacgttg gctgcggcgg ctgacaacaa tacggcaaaa gacgaaaaag cggatgatct
     8761 gaatgaagac gtcaccgcca gcctgagtgc cctttttgcg atgttgccgg gttttgacaa
     8821 tacgcccaaa gtgactgatg caccgtcaac cgtattaccg acagagaaac caacgctctt
     8881 cacaaaactg acttctgcgc aactcacaac agcacagcct gatgacgccc ccggcacgcc
     8941 agctcagcca ttaacaccgc tgatagcaga agcccagagt aaagcggaaa tcatcagcac
     9001 gccttcgccg gtgaccgctg ccgccagccc gctaatcact ccacaccaga cacagccact
     9061 gcccaccgtc gccgcgcctg ttttgagtgc accgctgggt tctcacgaat ggcaacaatc
     9121 attaagccag catatttcgc tgttcacccg ccaggggcaa caaagtgcag agttgcgtct
     9181 gcacccgcag gatttaggtg aggtgcaaat ctccctcaaa gtggatgata accaggcgca
     9241 aatccagatg gtttcaccgc atcagcatgt acgcgccgcc ctggaagcag cgctgccggt
     9301 actgcgtacg cagctggccg aaagtggcat tcagttaggg caaagcaaca tcagtggcga
     9361 aagctttagt ggtcagcagc aggccgcttc ccaacaacag caaagccaac gcacagtaaa
     9421 ccatgaacct ctggcggggg aagaagacga tacgcttccg gttcccgtct ctttacaagg
     9481 gcgcgtaaca ggcaacagcg gcgttgatat tttcgcctaa cgtcagaggt agcaccgtaa
     9541 tccgcgtctt ttccccgctt tgttgcgctc aagacgcagg ataattagcc gataagcagt
     9601 agcgacacag gaagaccgca acacatgact gattacgcga taagcaagaa aagcaagcga
     9661 tcgctttgga tcccgattct ggtattcatt accctcgcgg cctgtgccag cgcaggttac
     9721 agctactggc attcgcatca ggttgccgct gacgacaaag cgcagcaacg cgtcgtgccc
     9781 tccccggtct tctatgcgct ggataccttt acggtcaatc tgggcgatgc ggatcgcgtg
     9841 ctgtatatcg gcataaccct gcgcctgaaa gatgaagcta cacgctcgcg gctgagtgag
     9901 tatttgccgg aagtccgtag ccgtttgctg ttactgtttt cgcgtcagga tgctgccgta
     9961 ctggcgacag aagaaggcaa gaaaaacctg attaccgaga ttaaaaccac gctttccacc
    10021 ccgcttgttg ccgggcaacc gaaacaggat gtcaccgacg tgctgtatac cgcttttatt
    10081 ctgcgataac gacatgggcg atagtattct ttctcaagct gaaattgatg cgctgttgaa
    10141 tggtgacagc gaagtcaaag acgaaccgac agccagtgtt agcggcgaaa gtgacattcg
    10201 tccgtacgat ccgaataccc aacgacgggt tgtgcgcgaa cgtttgcagg cgctggaaat
    10261 cattaatgag cgctttgccc gccattttcg tatggggctg ttcaacctgc tgcgccgtag
    10321 cccagatata accgtcgggg ccatccgcat tcagccgtac catgaatttg cccgcaacct
    10381 gccggtgccg accaacctga accttatcca tctgaaaccg ctgcgcggca cagggctggt
    10441 ggtgttttca ccgagtctgg tgtttatcgc cgtggataac ctgtttggcg gcgatggacg
    10501 cttcccgacc aaagtggaag gtcgcgagtt tacccatacc gaacagcgcg tcatcaaccg
    10561 catgttaaag ctggcgcttg aaggctatag cgacgcctgg aaggcgatta atccgctgga
    10621 agttgagtac gtgcgttcgg aaatgcaggt gaaatttacc aatatcacca cctcgccgaa
    10681 cgacattgtg gttaacacgc cgttccatgt ggagattggc aacctgaccg gcgaatttaa
    10741 tatctgtctg ccattcagca tgatcgagcc gctacgggaa ttgttggtta acccgccgct
    10801 ggaaaactcg cgtaatgaag atcagaactg gcgcgataac ctggtgcgcc aggtgcagca
    10861 ttcacagctg gagctggtcg ccaactttgc cgatatctcg ctacgcctgt cgcagatttt
    10921 aaaactgaaa cccggcgacg tcctgccgat agaaaaaccc gatcgcatca tcgcccatgt
    10981 tgacggcgtc ccggtgctga ccagtcagta cggcactctc aacggtcagt atgcgttacg
    11041 gatagaacat ttgattaacc cgattttaaa ttctctgaac gaggaacagc ccaaatgagt
    11101 gacatgaata atccggctga tgacaacaac ggcgcaatgg acgatctgtg ggctgaagcg
    11161 ttgagcgaac aaaaatcaac cagcagcaaa agcgctgccg acgcggtgtt ccagcaattt
    11221 ggcggtggtg atgtcagcgg aacgttgcag gatatcgacc tgataatgga tattccggtc
    11281 aagctgaccg tcgagctggg ccgtacgcgg atgaccatca aagagctgtt gcgtctgacg
    11341 caagggtccg tcgtggcgct ggacggtctg gcgggcgaac cactggatat tctgatcaac
    11401 ggttatttaa tcgcccaggg cgaagtggtg gtcgttgccg ataaatatgg cgtgcggatc
    11461 accgatatca ttactccgtc tgagcgaatg cgtcgcctga gccgttagtg atgaataacc
    11521 acgctactgt gcaatcttcc acgccggttt ctgctgcgcc actgctgcag gtcagcggcg
    11581 cactcatcgc cattattgcc ctgatcctcg ctgctgcctg gctggtaaaa cggttgggat
    11641 ttgccccgaa acgcactggc gttaacggtc tgaaaattag cgccagtgct tcgctgggcg
    11701 cgcgtgaacg ggttgtggtg gtcgatgtgg aagatgcacg gctggtgctc ggcgttaccg
    11761 cagggcaaat caatctgctg cataaacttc ccccttcagc accaacagaa gagataccgc
    11821 agaccgattt tcagtcggtc atgaaaaatt tgcttaagcg tagtgggaga tcctgatgcg
    11881 tcgtttgttg tctgtcgcac ctgtccttct ctggctggtt acgcccctcg ccttcgcgca
    11941 actgccgggt atcaccagcc agccgctgcc tggcggtgga caaagctggt cgctcccggt
    12001 gcagacgctg gtgttcatca cctcgttgac gtttattccg gcaattttac tgatgatgac
    12061 cagtttcacc cgcatcatca ttgtttttgg tttattgcgt aacgcgctgg gaacgccctc
    12121 cgcgccacct aaccaggtat tgctggggct ggcactattt ttgacctttt ttattatgtc
    12181 accggtgatc gacaaaattt atgtcgatgc gtaccagcca ttcagcgaag agaaaatatc
    12241 aatgcaggag gcgctggaaa aaggggcgca gccgctgcgt gagtttatgc tgcgtcagac
    12301 ccgtgaggcg gatttagggt tgtttgccag actggcgaat actggtccgt tgcagggacc
    12361 tgaagccgtg ccgatgcgca ttttgctccc ggcctacgtg accagcgagt tgaaaaccgc
    12421 atttcagata ggcttcacga ttttcatccc ttttttgatt atcgacctgg tgattgccag
    12481 cgtgttgatg gcattgggga tgatgatggt cccccccgcc accattgctc tgccctttaa
    12541 actgatgctg tttgtactgg tggatggctg gcaattgctg gtcggttcgc tggcgcagag
    12601 cttttacagc tagagaggca aaatgacacc tgaatcggtc atgatgatgg ggactgaagc
    12661 gatgaaagtc gcgctggcac tggctgcccc gctgttgctg gtggcgctgg tcacgggcct
    12721 tatcatcagt attttgcagg ccgccaccca gatcaacgaa atgacgctgt cgtttattcc
    12781 aaaaatcatc gccgtattta ttgccattat tattgccgga ccgtggatgc tcaatctgtt
    12841 gctggattac gtccgcacct tgttcactaa cctgccgtat atcatcgggt agccgtacta
    12901 tgttgcaggt gacaagcgaa caatggctat cctggttaag cctctacttc tggccgttac
    12961 tgcgcgtgct ggcgctcatt tctaccgcgc caattgtgag cgaacgcagc gtgccgaaac
    13021 gggtaaaact gggtctggca atgatgatca cgttcgcaat tgccccatca ttacctgcca
    13081 acgatgttcc tgttttttcg ttctttgctc tgtggctggc cgtgcagcag atcctgatcg
    13141 gcattgcgct tggttttacc atgcaatttg cctttgccgc tgtgcgaacc gctggcgaaa
    13201 ttatcggcct gcaaatgggg ctgtcatttg cgacgtttgt cgatccggcc agccatctca
    13261 atatgcccgt tttagcgcgt atcatggata tgctggcgtt attgctgttc ctgacattta
    13321 acggtcattt atggttaatt tcactgctgg tcgatacctt tcacaccctg ccaattggtg
    13381 gcgaaccgtt gaacagcaat gcgtttctgg cactcaccaa agcagggagt ttgattttcc
    13441 ttaacgggct gatgctggcg ttaccgctca ttactctgct gctgaccctg aatctggcat
    13501 taggtttact gaatcgtatg gccccgcaat tatccatttt tgttattgga tttccattaa
    13561 ctctgactgt cggtatctct ttaatggcgg cattaatgcc gttaattgcg tctttttgcg
    13621 aacatttatt cagtgaaatt tttaatttgc tggctgatat tattagtgaa ttgccattaa
    13681 tataattccg taacgtttat catgttatcc taaggattat ccgaaaaata atacctacga
    13741 acatcttcca ggatactcct gcggcgaaat atttgtttta agctcactca catatcgcaa
    13801 catttacttt actttaagac aattccaggc aaattataca acactttacg ggatagtaag
    13861 tccgcctgaa aaatcgcgag agtggcgcat taggtgaccc atgttgttcc gtttagtcat
    13921 gatgaaatat tcaggtaagg ggaattatcg ttacgcattg agtgagggta tgccatgtca
    13981 atgattatta tggatttatg tagttacacc cgactaggtt taaccgggta tctgttgagt
    14041 agaggggtta aaaaaagaga aatcaacgac attgaaaccg ttgatgacct tgccatagct
    14101 tgtgattcac agcgcccttc agtggtgttt attaatgagg actgtttcat ccatgatgct
    14161 tctaacagtc agcacatcat taatcaacat cccaatacgt tatttatcgt ttttatggca
    14221 attgccaatg ttcattttga tgaatatcta ttggtcagaa aaaatttatt gatcagttct
    14281 aaatcgatta aaccggaatc tcttgacgat atccttggcg atattctgaa aaaagagaca
    14341 acgataacct cgtttttaaa tatgccgacg ttatcattga gccgaaccga atcgagtatg
    14401 ttgcgaatgt ggatggcagg tcagggaacc attcaaatct ctgaccaaat gaatatcaaa
    14461 gccaagaccg tttcatcgca taaaggtaat attaaacgta agatcaaaac gcataataaa
    14521 caggttatct accatgtcgt ccgactgacg gataatgtga ctaatggtat ttttgtcaac
    14581 atgcgctaac acattctgac tggtggtttc ccaccagtca ggctgaataa gattactctg
    14641 ctttctccac aaagataccg tcctgatgcc ctgcttcatt aaagaaccag atgccgagcg
    14701 ggtagtcttc cagcgaaacc aggtacattg tgccttcact aaactcctca actgccagta
    14761 ccacgccagg acgacgcgga ccgccatccg ttttgactgt tacccgatca ttcaccttca
    14821 tcgttttcct cctgtggctt tgtgccagtg tagaacaatt tcgtttttct ggcagcgcca
    14881 gccgcgcgcg agtgctgatt ttctcgacgg tctatactta agagatgcca ggcggactta
    14941 acgactggcg gcaacaacag agtaacggtt gcgaggaaag atgatgaaaa ccgcaaaaga
    15001 gtacagcgat accgcaaaac gtgaggtcag cgtcgatgtc gatgccctgc tggcggcgat
    15061 caatgaaatt agcgaaagcg aagttcatcg cagccagaac gattctgaac acgttagcgt
    15121 cgatggacgt gaatatcata catggcgtga attggcggat gccttcgaac tggatattca
    15181 tgacttcagc gtctctgaag tgaatcgttg aatgcacaat aaaaaaatcc cgaccctgag
    15241 ggggtcggga tgaaacttgc ttaagcaaga agcacttaaa aaattcgtta caccaggaaa
    15301 tctgatgtgt tcatcacctt atccgcaatt tttttcgctg acaagaaaat attcgccata
    15361 tgaatgatta acgctactta tgaatagaaa tgtgacgcac gtcacccctt ggtggctctg
    15421 gcgtcagcgg gatcgctccc gaaaaaatca tctttgataa tttgtgctgt tttgagaatc
    15481 atcctggtaa ggggagtact gcgcgactat gttttcaatt caacaaccac tactggtttt
    15541 tagcgatctt gatggcaccc tgctggatag tcatagttat gactggcaac cggcagcccc
    15601 tagctcaccc gtttacgcga agcaaatgta cccgtcattc tgtgtagtag taaaacttca
    15661 gcagaaatgc tgtacttgca aaaaatgttg gggctacaag gcttaccgct gattgcagag
    15721 aatggcgcag tgatccagct tgctgaacaa tggcaggaga tagacggttt tccacgcatc
    15781 atctcaggta ttagccatgg cgaaatcagc caggttttaa atacgctacg cgagaaagaa
    15841 cattttaaat tcacaacttt tgatgatgtc gacgatgcaa ccatcgccga atggacggga
    15901 ttaagccgta gccaggcggc gctgacgcag cttcatgagg cgtcggtaac gctaatctgg
    15961 cgcgacagtg acgagcgtat ggcacaattt accgcgcgtc tgaacgaact gggcttacag
    16021 tttatgcagg gtgcgcgctt ctggcatgta ctggatgcct ctgccggaaa agatcaggct
    16081 gccaactgga ttatcgcgac ttatcaacaa ttgtcaggca aacgcccaac cacacttggc
    16141 ctgggcgatg ggccaaacga tgcgccctta ctggaggtaa tggattacgc ggtgattgtg
    16201 aaagggctaa accgtgaagg ggtgcatctg catgatgagg atccggcccg cgtctggcga
    16261 acgcagcgtg aaggaccgga aggctggcgt gaagggctgg accatttttt ctccgcccgt
    16321 taagcgttat cgctcgcgca tacccgatta cgcccggcct gtttagcgag ataaagccga
    16381 cggtcagcca gtgactggag ttgttcaaaa tcataatcac cggtttcctc gctgctgctt
    16441 acccccagcg aggcactgat gcgtatcgtc gtactcttag cgatcaacat ctctttttca
    16501 ttcaacttca ggcgaatacg ttctgcgact gccgcagcct ccgtcagact cgcgcctggc
    16561 agaatcacac aaaactcctc accaccgacc cgcccggcaa cgtcctgcgc acgcaaggaa
    16621 ctgctaatta atccggcagc atgagaaaga acacggtcgc ccgcctgatg accaaagcgg
    16681 tcattaatcg ctttaaaatg gtcaaggtcg acctgaatga cagaaaaagg atgttggtgc
    16741 gtctgacaca atttcgcgag cggacgggct ttttcaaaca gtgcgccacg attatataaa
    16801 cgggttaagg tgtcgtgcca cgcctgccac tgcaacgagc tttgcagaac atacatgttg
    16861 ctaaccatcc ggcgaatcac ataccaggag atgagtaaca tggtggtaaa gagcgcccac
    16921 agcagggtta atgcaatgct gatactgccg aaatcgccgc gcacgccttc gcttagcgta
    16981 tggacgcgca ccagcacacc gtcgaaatgg tccagacgtt cccagctaac atagcgactg
    17041 tccatacgaa tgccgccccg cgtgtcatgt tccatcgcct gcgccagcaa ggccagttca
    17101 cgaggatcaa aaatattccc tgttggatgg tcaggattgg aagaggtcaa aaatctcagc
    17161 ttactgtcat agagctgata ctcaccatcg aggtttttat cgatggcgtt tcttaaaaat
    17221 tgctgcatgg tacgcacggg aatactcatc cccagcacgc cataccagta gttattactg
    17281 tctactggaa cactgacggt aacctgcggt tcagtattgc tggcgtgttc cggttgcgaa
    17341 gtaaaccagc gtaccgcgcg gtgacgattt tctcgttgcg aatggccgat aaaccagggt
    17401 tgggtgacat agccgtaata acgcgttggt acattgcgcg taaacaaggt cggctgcgtc
    17461 gaaacgtaaa atccggcacg cgagacatac atcgcctgtt caaccatcga cgaggtgttg
    17521 tgcgccagtc gcagcaagta accaacttcc agtgcagcgg taatttcatt gtcgaggctt
    17581 tcattttcgc gagacaggag attcccctcg ctgactaatg catccgatac gccattgact
    17641 gacagggtgc gtcgtcggtt gagttcaatt tgctaggcgt gctcgtcgcg atgctgttcg
    17701 aactcggtta cagcattacg cagtgaagtg aaatccagtg gcgctacgag agcttcgcgc
    17761 atgccattac gcaaaaagat cagtttgtcg acgttatact gcaaatgctt atcgagcgcg
    17821 ttggctacgt tttccagatg attacgctgg ctggagatat aggcatcttc cagcaccact
    17881 acttcacgcc aggtgagcaa ggtggaaaaa agcaatacca cgataaagca gagattaacg
    17941 acatgaccag gccccaggcg gcgtgcgagt tttttcaacc agctctggtt ttccattttt
    18001 gtctcgtgct gcaccctgac gactcccaac ctgctttttt atgattctgg cataacctgg
    18061 cgatagcgta ccgcaaaaca gcgataattt tataatggtg gcatgataag acgcgacaga
    18121 catcgatagt tttataacgt aggcatgata agacgcgata gcgtcgcatc aggcaattca
    18181 gtgcagacac tggcacaccc gaccggatgc gacgtgagcg ccacatccgg tcgggtgtta
    18241 atgataccct ttcaaacttc ttccgcagaa cgactcccct cccccggaac aagctcggtt
    18301 tcatgaaaag cttcccgctt gaccccgtaa ccgtcatacc aacgacactc aaccataccg
    18361 ctggagtatc cggtgacaat catccgcggg ccgccctctt taaccgtaac ttcctcacta
    18421 accataaagc tcatactcgc ctcctttttt cgagtgaaac ttgttcacct tagttgaaga
    18481 tggcgaattt tgcataatag cctgtgcgag tattaatgtg cctgaccgcg tattttcgct
    18541 acggctttca ctcccagcac cacgatgccg ccgatgataa atccaagaat cagatttaaa
    18601 acagtcggta atatcatcgc caccactgca ctttgctgcc cggcgaaatg ttcaatggcg
    18661 tgatgcagcg gcgcaatacc atgtaccaca atcccgccgc cgacgaggaa catcgccagc
    18721 gtgccgacaa tcgataacgc cttcatcaac cagggcgcaa tgatcaataa ccctttacct
    18781 aatgcctgca tcagcgcgct ggatttttcc gccagccaat accccaggtc atcaatctta
    18841 acgataaccc ctaccagacc gtagacgccc acggtcacta ccagcgcgat gcctgaaagc
    18901 accagcacct gattaagcaa cggcgcttcg gccacaatcc ccagcgtgat ggcgacgatt
    18961 tcggcagaca atataaaatc ggtacgaatc gcccctttta ttttgtcctt ttcaaacttc
    19021 agcggatcct gcgccgccag cttctccaga cgctgctggc tctgcgccgg atcttcttta
    19081 tgtttacgcg cctccagcat atgcagcact ttctctactc cttcaaagca gagaaacgcg
    19141 ccaccaatca tcaacagagg cgtaatcgcc cacgggataa acgcactgat gatcagcgcc
    19201 agcggcacca gaatcacttt attaatcagc gatcctttcg ccacgcccca gaccacggga
    19261 agttcccggt tggcccgcac gcctgaaact tgttgcgcat tgagcgataa gtcatcccct
    19321 aatacaccgg cggttttctt cgccgccagt ttgcccatca cggagatatc gtccagcagt
    19381 gtggcgatat catcgagcaa cgtcagtaaa ctactcccgg ccaaaagcat tccctctcat
    19441 ttttattgtt gaagggtgta agtatgaagc aaaaacggca gctctgatac ttgcttcaca
    19501 ggtcaacatt tttttaacaa tcaagtgcaa ttatatctct cgccagcaga atgattttca
    19561 cgtttactat gaaccacctt tttatttcca ccgtgaggga ttatgcgttt ccgccagttg
    19621 ttaccgcttt ttggcgcgct gtttgcgttg tatatcattt ggggctcaac ctattttgtc
    19681 attcggattg gcgtggaaag ctggcctccg ttaatgatgg cgggcgttcg attcctggca
    19741 gccggtattt tattgctggc atttttgcta ctgcgcggac acaagctccc cccgctacgt
    19801 ccgctgctca atgccgcgct gattggcctg ttattgctgg ctgtcggtaa tggcatggtg
    19861 acggttgccg aacatcaaaa tgttccttcc ggcatcgccg ccgtagtggt tgcaaccgta
    19921 cccctcttta ccctgtgctt cagccgcctg tttggcatta aaacgcgcaa actggaatgg
    19981 gtgggtattg ccattgggct tgccggaatc atcatgctca atagcggtgg aaatttaagc
    20041 ggcaatccgt ggggcgcgat tctgatttta atcggctcga ttagctgggc gtttggctca
    20101 gtttatggct cgcgcattac cttacctgta gggatgatgg cgggtgcgat tgagatgctg
    20161 gcggcaggcg tggtgttaat gatcgcgtcg atgattgcag gtgaaaaact gacggcgctc
    20221 ccttcccttt caggcttcct tgcggtcggc tatctggcgc tgtttggttc gattatcgcc
    20281 attaacgctt atatgtattt aatccgcaac gtcagtccgg ctctcgccac cagctacgcc
    20341 tacgttaacc cggtggtcgc ggtcttgctg ggtacgggac tgggcggaga aacgctgtcg
    20401 aagattgaat ggctggcgct cggcgtaatt gtcttcgcgg tggtactggt cacgttggga
    20461 aaatatctct tcccggcaaa acccgtagtt gcgccagtta ttcaggacgc atcaagcgag
    20521 taaatgaatc ccctgcgtgt cgatctgcgc gctggcacct tcgccgcaga tccactcttc
    20581 cagacgctcg gtaagcgctt catccgtcag cttctcgcgc ccacgtaatg cacactccca
    20641 gacaatcaat acgcgccagc cgagttcctg caaacgactg atatcgcggc gatcgcgttc
    20701 aacattttta cttatcttct ccagccagaa ctcggttcga gtcgcaggca ctttaaacag
    20761 atagcagtga tgatggtgcc agaagcagcc gtgggtaaat atcacgcaac gatattcatc
    20821 aacgacaaaa tccggacgtc cgggcagact ggcgtcctga acgcgaaatg ccaggccctg
    20881 cccggttaac agactggcga ggcgcttctc tatcgccgta tcacgcgtgg caatcgcgcg
    20941 catatttttg ctgcgagtgg ccttatcgtg aacgtcggcc atgttgtgcc tcttgctgac
    21001 gcaacgccac cgcctgtttg atttttggct caagcagttt tgccaccgcg gcaaagaccg
    21061 gcacgaccac cgagttaccg aactggcgat aggcctgagt gtccgaaacc ggaatgcgga
    21121 atttcgcttc tcccggcgct tcaaaaccca ttaagcgcgc gcattcccga ggcgttaacc
    21181 gacgtggacg atgttgctga ttctgcggat cgtcaaagtc tttctcacct ttggccatat
    21241 cccagccgcg atcgattaaa atttccgcgc catctttgta ataacgcgca gacagcgtac
    21301 gcgtgacgct ttgcggattg ttcggataaa ccattccata accgaagccg ttaccgcgcg
    21361 cctgatgttt tttcgcatat cgatagaggt acttccacag caccggcgtc aggatatatt
    21421 tcgcctcgac catcgggtcc aacagctgcg ccagcgtcac tcgctgcgca gggaaacatt
    21481 cgctgatatc acgcagggta aaatcggctt tcagattcag atcgcgacga aaacccacca
    21541 gcacgatgcg ttcacggtgc tgcggcagaa aatgtttgcc gtcgatgatt ttcggatcgt
    21601 ctggcccatt atcttctgca tcagccacgt catagcccag ttcgtccagc gtctgcatga
    21661 tgatgcggaa cgttttaccc tggtcgtgac ttttcaggtt tttgacgttt tcgagcacaa
    21721 acatcgccgg acgacgcgcg tcgataatgc gtaccacatc aaaaaacagc gtgccctggg
    21781 tatcgcaggc aaaaccgtgc gcccgcccga gcgagttctt tttcgatacg ccagccagcg
    21841 aaaatggctg acaagggaaa ccggccagta aaacatcgtg ttcaggaatg tgttgacgaa
    21901 tatgttccgc cgccgcctca tcactcacgc cttctttatg gctgagggtg atgtcgcgga
    21961 tatcttcatt aaaatgatgc gtcgccggat cgcaataatg gttggcttta taagtgcgta
    22021 ccgcatgttt gttccattcg ctggtaaaca cgcactgtcc gccaatcgat tcaaaaccgc
    22081 gacggatgcc gccaattccg gcgaatagat cgataaagcg aaacgcataa tgcggatgat
    22141 gtgccggtgg tttgggtaat aacgtttgca gatgggcgaa ctctttctca cttaaacggt
    22201 gccatgccga gtcattcgcc agcgcacgtt ttaaaattgc cgcgctccag tgattctcac
    22261 ctacaccatt aagctgcgcc accaacgttt taacatcata aatttgcagc agtttctcca
    22321 gcattgcctg tgcggcattc ccggtgctgt atgaatcggt tactgatata ttttcctgca
    22381 tagatttcac cggccatctg agatggccga caggttaaca taattacagc catttagggc
    22441 cacgcgctca gccagcggat gaaaacgcat ctatcacctt gtgatcgaca ccttcattct
    22501 cccccgccag ttcggcactg agcttcgcca taaactcgac taaaaaatgc gcgttgtgct
    22561 gcgccagctg cttgcctctt gcggtttgca tggtttgcgg tagcttcagc aacttagtct
    22621 ggaaatgatc cagcgcgtag cgtttatcat caagcgggcg atgctgtgcg aacggatctt
    22681 caccatcaaa cagcgccacg cccaatgccc ctgaaacggc aaacacgcgc gccaggccaa
    22741 tcgcccccag ggcttccagc cgatccgcat cctggacaat tttagcttcc gttgttaagg
    22801 gggcgatttg cgcgctgaaa ctgtgagcgg caatggcatg acaaacggcc tcgattttct
    22861 ccgccggaaa ttgctcgaac tcttcacgga gcaggcgacg cgtctcttct gccgccagga
    22921 ttgaagaacg ctgcctttgc ggatgatttt tcgccaggct cacaatatcg tgaaaataac
    22981 aggcggttaa aatcaccagc atatcgacat cgtcatctgc cgccagcttc tgtgccgtag
    23041 cccagacgcg gcgaaaatga cacacgtcat gggccgcgtc ctggtgctga tgatggtttt
    23101 tcaaccagtt ttcgaactgt gcctgccagt gttgtaagtc catacgcgct ccgttgccaa
    23161 agagtcgcca ccttagcagt ttttattcat agcgtctgct acgtgcggga cgaggtcggg
    23221 tgtaccaggc aatgctgcct aacaatgccc cgaccagagc cataaataaa aatccgacca
    23281 gtgcccctaa ccactttccc gcggtagagc ctaaatcgct ttcaaatccc gacacggggg
    23341 catcggggat ccggctcatc acccagatgt aacgcgccat tgcccagacg aaatagccac
    23401 accatgtata gaaagcccac aaagccagtt tgccgccagg gctgcgagag agtctctctt
    23461 ccatctttgt cgaaccgtat tccattttga gataacccgg aaaactcaga cttagtacta
    23521 ttatgtgata aaagtcacat ttttccacat tggatgagcc agtcaagact cactcatttt
    23581 ttgaacaaat agataatttt tgcgcaacgg cagtgaatac aggaaaaatc gttttgagcg
    23641 attttattta tctttgatat cggctttatt aattcattta atc
//
LOCUS       DAPOAV010000069        23341 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.069, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000069 DAPOAV010000000
VERSION     DAPOAV010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23341
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.069"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(536..1627)
                     /gene="ychF"
                     /locus_tag="RN951_003111"
     CDS             complement(536..1627)
                     /gene="ychF"
                     /locus_tag="RN951_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001538644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HDX2528077.1"
                     /translation="MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVV
                     PMPDPRLDQLAEIVKPQRTLPTTMEFVDIAGLVKGASKGEGLGNQFLTNIRETEAIGH
                     VVRCFENDNIIHVSGKVNPADDIEVINTELALADLDTCERAIHRVQKKAKGGDKDAKA
                     ELAVLEKCLPQLENAGMLRALDLSAEEKAAIRYLSFLTLKPTMYIANVNEDGFENNPY
                     LDQVREIAAKEGSVVVPVCAAVEADIAELDDEERDEFMQELGLEEPGLNRVIRAGYKL
                     LNLQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAQTISFEDFITYKGEQ
                     GAKEAGKMRAEGKDYIVKDGDVMNFLFNV"
     gene            complement(1744..2328)
                     /gene="pth"
                     /locus_tag="RN951_003112"
     CDS             complement(1744..2328)
                     /gene="pth"
                     /locus_tag="RN951_003112"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDX2528078.1"
                     /translation="MTIKLIVGLANPGAEYAATRHNAGAWFVDLLAERLRAPLREEAK
                     FFGYTSRVTLGGEDVRLLVPTTFMNLSGKAVAAMASFFRINPDEILVAHDELDLPPGV
                     AKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRIGIGHPGDKNKVVGFVLGKPPVSEQK
                     LIDEAIDEAARCTEMWFTDGLTKATNRLHAFKAQ"
     gene            2606..2884
                     /gene="ychH"
                     /locus_tag="RN951_003113"
     CDS             2606..2884
                     /gene="ychH"
                     /locus_tag="RN951_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress-induced protein YchH"
                     /protein_id="HDX2528079.1"
                     /translation="MKRKNASLLGNVLMGLGLVVMVVGVGYSILNQLPQFNMPQYFAH
                     GAVLSIFVGAILWLAGARVGGHEQVCDRYWWVRHYDKRCRRSDNRRHS"
     gene            complement(2939..4618)
                     /gene="dauA"
                     /locus_tag="RN951_003114"
     CDS             complement(2939..4618)
                     /gene="dauA"
                     /locus_tag="RN951_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylic acid transporter DauA"
                     /protein_id="HDX2528080.1"
                     /translation="MNKIFSSHVMPFRALIDACWKEKYTAARFTRDLIAGITVGIIAI
                     PLAMALAIGSGVAPQYGLYTAAVAGIVIALTGGSRFSVSGPTAAFVVILYPVSQQFGL
                     AGLLVATLLSGIFLILMGLARFGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQM
                     AHVPEHYLQKVGALFMALPTINVGDAAIGIVTLGILVFWPRLGIRLPGHLPALLAGCA
                     VMGIVNLLGGHVATIGSQFHYVLADGSQGNGIPQLLPQLVLPWDLPNSEFTLTWDSIR
                     TLLPAAFSMAMLGAIESLLCAVVLDGMTGTKHKANSELVGQGLGNIIAPFFGGITATA
                     AIARSAANVRAGATSPISAVIHSILVILALLVLAPLLSWLPLSAMAALLLMVAWNMSE
                     AHKVVDLLRHAPKDDIIVMLLCMSLTVLFDMVIAISVGIVLASLLFMRRIARMTRLAP
                     VVVDVPDDVLVLRVIGPLFFAAAEGLFTDLESRLEGKRIVILKWDAVPVLDAGGLDAF
                     QRFVKRLPEGCELRVCNVEFQPLRTMARAGIQPIPGRLAFFPNRRAAMADL"
     gene            complement(4743..5690)
                     /gene="prs"
                     /locus_tag="RN951_003115"
     CDS             complement(4743..5690)
                     /gene="prs"
                     /locus_tag="RN951_003115"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HDX2528081.1"
                     /translation="MPDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQI
                     NENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVR
                     SARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLN
                     LDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVL
                     VDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIP
                     LSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH"
     gene            complement(5841..6692)
                     /gene="ispE"
                     /locus_tag="RN951_003116"
     CDS             complement(5841..6692)
                     /gene="ispE"
                     /locus_tag="RN951_003116"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HDX2528082.1"
                     /translation="MRTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTISIE
                     LRDDGDIRLLTPVEGVEHEDNLIVRAARLLMKTAADSGRLPTGSGANISIDKRLPMGG
                     GLGGGSSNAATVLVALNHLWQCGLSMDELAEMGLTLGADVPVFVRGHAAFAEGVGEIL
                     TPVDPPEKWYLVAHPGVSIPTPVIFKDPELPRNTPKRSIETLLKCEFSNDCEVIARKR
                     FREVDAVLSWLLEYAPSRLTGTGACVFAEFDTESEARQVLEQAPEWLNGFVAKGANLS
                     PLHRAML"
     gene            complement(6692..7315)
                     /gene="lolB"
                     /locus_tag="RN951_003117"
     CDS             complement(6692..7315)
                     /gene="lolB"
                     /locus_tag="RN951_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein localization protein LolB"
                     /protein_id="HDX2528083.1"
                     /translation="MPLPDFRLIRLLPLAALVLTACSVTTPKGPGKSPDSPQWRQHQQ
                     DVRNLNQYQTRGAFAYISDQQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGN
                     VQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEI
                     TYSQNGKNWKVVYGGYDTKTQPAMPANMELTDGGQRIKLKMDNWIVK"
     gene            7529..8785
                     /gene="hemA"
                     /locus_tag="RN951_003118"
     CDS             7529..8785
                     /gene="hemA"
                     /locus_tag="RN951_003118"
                     /EC_number="1.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_041689438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA reductase"
                     /protein_id="HDX2528084.1"
                     /translation="MTLLALGINHKTAPVSLRERVSFSPDKLDQALDSLLAQPMVQGG
                     VVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLNEEDLRKSLYWHQDNDAVSHLMR
                     VASGLDSLVLGEPQILGQVKKAFADSQKGHMKASELERMFQKSFSVAKRVRTETDIGA
                     SAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRER
                     AQILADEVGAEVIALSDIDERLREADIIISSTASPLPIIGKGMVERALKSRRNQPMLL
                     VDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRKAAAVEAETIVAQETSEFMA
                     WLRAQSASETIREYRSQAEQVRDELTAKALAALEQGGDAQAIMQDLAWKLTNRLIHAP
                     TKSLQQAARDGDNERLNILRDSLGLE"
     gene            8827..9909
                     /gene="prfA"
                     /locus_tag="RN951_003119"
     CDS             8827..9909
                     /gene="prfA"
                     /locus_tag="RN951_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012132158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HDX2528085.1"
                     /translation="MKPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQ
                     LSDVSRCFTDWQQVQEDIETAQMMLDDPEMREMAQDELREAKEKSEQLEQQLQVLLLP
                     KDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGGYK
                     EIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPDAELPDIN
                     PADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGA
                     RIHAAEMAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVME
                     GKLDMLIEPIIQEHQADQLAALSEQE"
     gene            9909..10742
                     /gene="prmC"
                     /locus_tag="RN951_003120"
     CDS             9909..10742
                     /gene="prmC"
                     /locus_tag="RN951_003120"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDX2528086.1"
                     /translation="MEYQHWLREAISQLQASESPRRDAEILLEHVTGRGRTFILAFGE
                     TQLTDEQCQQLDALLTRRRDGEPIAHLTGVREFWSLPLFVSPATLIPRPDTECLVEQA
                     LARLPEQPCRILDLGTGTGAIALALASERPDCEIIAVDRMPDAVSLAQRNAQHLAIKN
                     IHILQSDWFSALAGQQFAMIVSNPPYIDEQDPHLQQGDVRFEPLTALVAADSGMADIV
                     HIIEQSRNALVSGGFLLLEHGWQQGEAVRQAFILAGYHDVETCRDYGDNERVTLGRYY
                     Q"
     gene            10739..11131
                     /locus_tag="RN951_003121"
     CDS             10739..11131
                     /locus_tag="RN951_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SirB family protein"
                     /protein_id="HDX2528087.1"
                     /translation="MTSFSTLLSVHLISIALSVGLLTLRFWLRYQKHPQAFARWTRIV
                     PPVVDTLLLLSGIALMAKAHILPFSGQAQWLTEKLFGVIIYIVLGFIALDYRRMHSQQ
                     ARIIAFPLALVVLYIIIKLATTKVPLLG"
     gene            11135..11944
                     /locus_tag="RN951_003122"
     CDS             11135..11944
                     /locus_tag="RN951_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat-containing protein"
                     /protein_id="HDX2528088.1"
                     /translation="MRSLADFEFNKAPLCEGMILACEAIRRDFPSQDVYDELERLVSL
                     AKEEISQLLPLEEQLEKLIALFYGDWGFKASRGVYRLSDALWLDQVLKNRQGSAVSLG
                     AVLLWVANRLDLPLLPVIFPTQLILRIECPDGEIWLINPFNGESLSEHMLDVWLKGNI
                     SPSAELFYEDLDEADNIEVIRKLLDTLKASLMEENQMELALRTSEALLQFNPEDPYEI
                     RDRGLIYAQLDCEHVALNDLSYFVEQCPEDPISEMIRAQINNIAHKHIVLH"
     gene            11980..12834
                     /gene="kdsA"
                     /locus_tag="RN951_003123"
     CDS             11980..12834
                     /gene="kdsA"
                     /locus_tag="RN951_003123"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HDX2528089.1"
                     /translation="MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTV
                     TQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQA
                     QPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGN
                     EKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRR
                     AQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKG
                     FEELDTSK"
     gene            complement(12983..13090)
                     /locus_tag="RN951_003124"
     CDS             complement(12983..13090)
                     /locus_tag="RN951_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small toxic polypeptide LdrA/LdrC"
                     /protein_id="HDX2528090.1"
                     /translation="MTLAQFAMIFWHDLAAPILAGIITAAIVSWWRNRK"
     gene            complement(13518..13625)
                     /locus_tag="RN951_003125"
     CDS             complement(13518..13625)
                     /locus_tag="RN951_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small toxic polypeptide LdrB"
                     /protein_id="HDX2528091.1"
                     /translation="MTLAQFAMTFWHDLAAPILAGIITAAIVGWWRNRK"
     gene            complement(14053..14160)
                     /locus_tag="RN951_003126"
     CDS             complement(14053..14160)
                     /locus_tag="RN951_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small toxic polypeptide LdrA/LdrC"
                     /protein_id="HDX2528092.1"
                     /translation="MTLAQFAMIFWHDLAAPILAGIITAAIVSWWRNRK"
     gene            complement(14564..15664)
                     /gene="chaA"
                     /locus_tag="RN951_003127"
     CDS             complement(14564..15664)
                     /gene="chaA"
                     /locus_tag="RN951_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-potassium/proton antiporter ChaA"
                     /protein_id="HDX2528093.1"
                     /translation="MSNAQEAVKTRHKETSLIFPVLALVVLFLWGSSQTLPVVIAINL
                     LALIGILSSAFSVVRHADVLAHRLGEPYGSLILSLSVVILEVSLISALMATGDAAPTL
                     MRDTLYSIIMIVTGGLVGFSLLLGGRKFATQYMNLFGIKQYLIALFPLAIIVLVFPMA
                     LPAANFSTGQALLVALISAAMYGVFLLIQTKTHQSLFVYEHEDDSDDDDPHHGKPSAH
                     SSLWHAIWLIIHLIAVIAVTKMNASSLETLLDSMNAPVAFTGFLVALLILSPEGLGAL
                     KAVLNNQVQRAMNLFFGSVLATISLTVPVVTLIAFMTGNELQFALGAPEMVVMVASLV
                     LCHISFSTGRTNVLNGAAHLALFAAYLMTIFA"
     gene            15934..16164
                     /gene="chaB"
                     /locus_tag="RN951_003128"
     CDS             15934..16164
                     /gene="chaB"
                     /locus_tag="RN951_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cation transport regulator ChaB"
                     /protein_id="HDX2528094.1"
                     /translation="MPYKTKSDLPESVKHVLPSHAQDIYKEAFNSAWDQYKDKEDRRD
                     DASREETAHKVAWAAVKHEYAKGDDDKWHKKS"
     gene            16322..17017
                     /gene="chaC"
                     /locus_tag="RN951_003129"
     CDS             16322..17017
                     /gene="chaC"
                     /locus_tag="RN951_003129"
                     /EC_number="4.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415736.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-specific
                     gamma-glutamylcyclotransferase"
                     /protein_id="HDX2528095.1"
                     /translation="MITRDFLMNADCKTAFGAIEESLLWSAEQRAASLAATLACRPDE
                     GPVWIFGYGSLMWNPALEFTESCTGTLVGWHRAFCLRLTAGRGTAHQPGRMLALKEGG
                     RTTGVAYRLPEETLEQELTLLWKREMITGCYLPTWCQLDLDDGRTVNAIVFIMDPRHP
                     EYESDTRAQVIAPLIAAASGPLGTNAQYLFSLEQELIKLGMQDDGLNDLLVSVKKLLA
                     ENFPDGVLRPGFA"
     gene            complement(17061..17414)
                     /gene="ychN"
                     /locus_tag="RN951_003130"
     CDS             complement(17061..17414)
                     /gene="ychN"
                     /locus_tag="RN951_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE/F sulfur relay family protein YchN"
                     /protein_id="HDX2528096.1"
                     /translation="MQKIVIVANGAPYGSESLFNSLRLAIALREQESNLDLRLFLMSD
                     AVTAGLRGQKPGEGYNIQQMLEILTAQNVPVKLCKTCTDGRGISTLPLIDGVEIGTLV
                     ELAQWTLSADKVLTF"
     gene            17599..18993
                     /gene="ychO"
                     /locus_tag="RN951_003131"
     CDS             17599..18993
                     /gene="ychO"
                     /locus_tag="RN951_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415738.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inverse autotransporter invasin YchO"
                     /protein_id="HDX2528097.1"
                     /translation="MSRFVPRIIPFYLLLLVAGGTANAQSTFEQKAANPFDNNNDGLP
                     DLGMAPENHDGEKHFAEIVKDFGETSMNDNGLDTGEQAKAFALGKVRDALSQQVNQHV
                     ESWLSPWGNASVDVKVDNEGHFTGSRGSWFVPLQDNDRYLTWSQLGLTQQDNGLVSNV
                     GVGQRWARGNWLVGYNTFYDNLLDENLQRAGFGAEAWGEYLRLSANFYQPFAAWHEQT
                     ATQEQRMARGYDLTARMRMPFYQHLNTSVSLEQYFGDRVDLFNSGTGYHNPVALSLGL
                     NYTPVPLVTVTAQHKQGESGENQNNLGLNLNYRFGVPLKKQLSAGEVAESQSLRGSRY
                     DNPQRNNLPTLEYRQRKTLTVFLATPPWDLKPGETVPLKLQIRSRYGIRQLIWQGDTQ
                     ILSLTPGAQANSAEGWTLIMPDWQNGEGASNHWRLSVVVEDNQGQRVSSNEITLTLVE
                     PFDALSNDELRWEP"
     gene            complement(18994..19644)
                     /gene="narL"
                     /locus_tag="RN951_003132"
     CDS             complement(18994..19644)
                     /gene="narL"
                     /locus_tag="RN951_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator NarL"
                     /protein_id="HDX2528098.1"
                     /translation="MSNQEPATILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQG
                     IELAESLDPDLILLDLNMPGMNGLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRG
                     ADGYLLKDMEPEDLLKALHQAAAGEMVLSEALTPVLAASLRANRATTERDVNQLTPRE
                     RDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQERIF"
     gene            complement(19637..21433)
                     /gene="narX"
                     /locus_tag="RN951_003133"
     CDS             complement(19637..21433)
                     /gene="narX"
                     /locus_tag="RN951_003133"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarX"
                     /protein_id="HDX2528099.1"
                     /translation="MLKRCLSPLTLVNQVALIVLLSTAIGLAGMAVSGWLVQGVQGSA
                     HAINKAGSLRMQSYRLLAAVPLSEKDKPLIKEMEQTAFSAELTRAAERDGQLAQLQGL
                     QDYWRNELIPALMRAQNRETVSADVSQFVAGLDQLVSGFDRTTEMRIETVVLVHRVMA
                     VFMALLLVFTIIWLRARLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNN
                     MSAELAESYAVLEQRVQEKTAGLEHKNQILSFLWQANRRLHSRAPLCERLSPVLNGLQ
                     NLTLLRDIELRVYDTDDEENHQEFTCQPDMTCDDKGCQLCPRGVLPVGDRGTTLKWRL
                     ADSHTQYGILLATLPQGRHLSHDQQQLVDTLVEQLTATLALDRHQERQQQLIVMEERA
                     TIARELHDSIAQSLSCMKMQVSCLQMQGDALPESSRELLSQIRNELNASWAQLRELLT
                     TFRLQLTEPGLRPALEASCEEYSAKFGFPVKLDYQLPPRLVPSHQAIHLLQIAREALS
                     NALKHSQASEVVVTVAQNDNQVKLTVQDNGCGVPENAIRSNHYGMIIMRDRAQSLRGD
                     CRVRRRESGGTEVVVTFIPEKTFTDVQGDTHE"
     gene            21772..23163
                     /gene="narK"
                     /locus_tag="RN951_003134"
     CDS             21772..23163
                     /gene="narK"
                     /locus_tag="RN951_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate transporter NarK"
                     /protein_id="HDX2528100.1"
                     /translation="MSHSSAPERATGAVITDWRPEDPAFWQQRGQRIASRNLWISVPC
                     LLLAFCVWMLFSAVAVNLPKVGFNFTTDQLFMLTALPSVSGALLRVPYSFMVPIFGGR
                     RWTAFSTGILIIPCVWLGFAVQDTSTPYSVFIIISLLCGFAGANFASSMANISFFFPK
                     QKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAVFGSQGVKQPDGTELYLANASWI
                     WVPFLAIFTIAAWFGMNDLATSKASIKEQLPVLKRGHLWIMSLLYLATFGSFIGFSAG
                     FAMLSKTQFPDVQILQYAFFGPFIGALARSAGGALSDRLGGTRVTLVNFILMAIFSGL
                     LFLTLPTDGQGGSFMAFFAVFLALFLTAGLGSGSTFQMISVIFRKLTMDRVKAEGGSD
                     ERAMREAATDTAAALGFISAIGAIGGFFIPKAFGSSLALTGSPVGAMKVFLIFYIACV
                     VITWAVYGRHSKK"
BASE COUNT         5741 a         5836 c         5987 g         5777 t
ORIGIN      
        1 tattccaatt cgttactata aatatggcaa aaatattaca acaaacagcg gttaaaaaat
       61 ttggtgaaga ttttttgtaa taatcctaat tagttatggg aatttcgctt gatgtatctg
      121 cataacaaaa acaatatgcg ccatttttgc attactaata agaaaaagca aaaaacatcg
      181 atattcattt ttggtcaatg ggttttctgg cctatcgttg ttattgtgct actggttatc
      241 attttcatct tgccagcata ttggagcgtg atcaattttg atcagctgtg aagggggctg
      301 atgtgtagtg atacaaaaac ttacgttata tcactgctaa tgagatatcc gtcatctgaa
      361 cacttatgtc tttaattatt ctcgtggttc actataggca ataagcacaa aagtgtagga
      421 tgttacaaga atgattagga ctcggtgaaa tgaaaaatcc acgcaattgc gtggatttta
      481 tatacttttg cgctcttcat gagatttagc gaaacctcat gagacaataa attaattaga
      541 cgttgaaaag gaagttcatc acatcgccat ctttcacgat gtaatcttta ccttctgcac
      601 gcattttgcc tgcttctttc gcgccttgtt cacctttgta agtgatgaaa tcttcaaacg
      661 agatggtttg tgcacggata aagccttttt caaaatcagt atggattttg cccgctgcct
      721 gcggcgcggt tgctccaacc ggaatggtcc atgcacgcac ttctttcacc ccagcggtga
      781 agtaagtttg caggttcagc agtttataac cggcacggat cacacggttc aggcccggct
      841 cttccagccc aagctcctgc ataaactcgt cacgttcttc gtcgtccagt tcggcaatgt
      901 ctgcttcaac agcagcacaa accggaacca caacagaacc ttctttcgcc gcgatttcac
      961 gcacctggtc aagatatggg ttgttttcaa aaccgtcttc gttgacgttg gcgatgtaca
     1021 ttgttggttt cagcgtcagg aagctcaggt aacgaatagc cgctttctct tcagcgctta
     1081 aatccagcgc gcgcagcata cctgcatttt ccaactgggg caggcatttt tccaggaccg
     1141 ccagctcagc tttcgcgtct ttatcgccac ctttggcttt cttctgtacg cgatgaatcg
     1201 cacgttcgca ggtgtcgagg tctgccagcg ccagttcggt gttgataact tcaatatcgt
     1261 cagccgggtt aactttgccg gaaacgtgaa tgatgttgtc attttcaaag cagcgaacaa
     1321 cgtgaccgat cgcttcggtt tcacggatgt tggtcaggaa ctggttaccc agaccttcgc
     1381 ctttcgatgc gccttttacc agaccggcga tatcgacaaa ttccatggtc gtgggaagcg
     1441 tacgctgcgg ttttacgatt tcagccagtt gatccaggcg aggatcaggc attggtacga
     1501 cgcctgtgtt cggctcaatg gtgcagaatg gaaagttggc cgcttcaata ccggctttgg
     1561 tcagcgcgtt gaacagggta gatttcccga cgttgggcaa accgacgata ccgcatttga
     1621 atcccatgat ttaaatcacc ttaatatctt aataatcaac ctgttattgc taacagattg
     1681 cagaaatgga aataactttg cctattatac acggcactcg gcaaaaatgc cgcagacaac
     1741 gacttattgc gctttaaagg cgtgcaatcg gttcgttgct ttggtcaagc catctgtaaa
     1801 ccacatttca gtacaacgcg ccgcttcgtc aatggcttca tcaattaact tctgttcact
     1861 aacaggcggt ttgcctaaca caaaaccgac aactttattt ttatcgcccg gatgaccgat
     1921 tccgatgcgt aaacggtgaa agttagggtt attacccaat ttactgatga tgtctttcag
     1981 tccattgtga ccaccatggc caccgcccaa tttaaatttg gcgacgccag gaggcagatc
     2041 cagttcgtcg tgggccacca gaatttcgtc cggattaatg cggaaaaaac tggccatcgc
     2101 cgcaacggct ttgccgctga gattcataaa tgtagtcggg actaacaggc ggacatcttc
     2161 gcctccaaga gtgactcgcg aagtataacc aaagaattta gcctcttcgc gcagcggagc
     2221 gcgcaaacgc tctgccagta agtcaacgaa ccaggcacca gcattatgtc gcgttgcggc
     2281 gtattcagca ccggggttcg ccaggccgac aatcaattta atcgtcacgt ttttttgtcc
     2341 tgagtgtgta cataactggc gcgtagttta ctggttgcgg ccccgcttga caaaaaactg
     2401 cgtatcaaat gcagataacg taataattgc ctgagtggac tattagaaag tcaaggtgtt
     2461 caggcgttta tttgtaaagt tttgttgaaa taagggttgt aattgtgatc acgcccgcac
     2521 ataacccact gggtgttgtc tatactttac acataaggaa gaggggtatt ccctgttaca
     2581 acccagaaag ttccggaggt gacatatgaa acgcaaaaac gcttcgttac tcggtaacgt
     2641 gctcatgggg ttgggtctgg tggtaatggt ggtcggcgtg gggtattcaa tcctcaacca
     2701 gttaccacag tttaatatgc cccagtattt cgcacatggt gcagtgctaa gtattttcgt
     2761 cggtgccatt ctctggctgg cgggtgcccg tgttggcggg catgaacagg tgtgcgaccg
     2821 ttactggtgg gttcgccact atgacaaacg ttgccgccgt agcgataatc gccgtcatag
     2881 ctaacaaata atgcagtttg ctgaccagtc agtttgcgct gactggtcaa tctcgtactt
     2941 ataaatccgc catcgccgcg cgacgattcg ggaagaacgc caggcgtccc gggatcggtt
     3001 gaatgccagc gcgagccata gtgcgcagtg gctggaattc cacgttgcac acgcgcagtt
     3061 cacatccctc gggcagacgc ttcacaaaac gctggaacgc atcaagacca ccagcatcaa
     3121 gtaccggaac ggcatcccac ttcagaatca caatccgttt tccttcaaga cgtgactcca
     3181 ggtccgtgaa taagccttca gcagcagcaa aaaacagcgg gccaataacg cgcagaacca
     3241 ggacatcgtc tggaacatct acgactaccg gtgccaggcg agtcatacgt gcgatacgac
     3301 gcataaacag cagcgatgcc agcacgatcc ccacgctgat ggcaataacc atatcaaaca
     3361 acacggtcag cgacatgcac agcagcatga cgatgatgtc atctttcggc gcatgacgca
     3421 gcaagtcgac cactttgtgc gcttcactca tgttccacgc caccatcaac agcagggctg
     3481 ccatggcgga aagcggcagc caggagagca gcggtgccag taccagcagg gcaagaataa
     3541 ccagaataga gtggatcacc gccgagatag gggacgttgc cccggcacgg acgttagcgg
     3601 cagaacgcgc gatggcagct gtagcggtaa taccaccaaa gaacggagcg ataatattcc
     3661 ccagtccctg tccaaccagt tcgctgttcg ccttgtgttt cgtcccggtc ataccatcca
     3721 gcaccacggc gcagagcaga gattcgattg cgccgagcat tgccattgag aatgccgcag
     3781 gcagcagtgt gcgaatagaa tcccaggtta gcgtgaattc tgaattaggc agatcccacg
     3841 gcagcaccag ttgcggcagc agttgcggaa taccgttacc ctgagaacca tcggccagga
     3901 cgtagtggaa ttgcgaaccg atggtagcaa catgtccgcc gagcaggtta acaatcccca
     3961 tcaccgcgca accagccagc aaggccggaa ggtgaccggg taaacgaatg cccagacgcg
     4021 gccaaaaaac aagaatacct agcgtcacaa tgccaatggc agcatcaccc acattaatgg
     4081 tcggcagcgc cataaataat gcgccgactt tttgtagata atgttccggg acatgggcca
     4141 tttgcagacc gagaaaatct ttaatctgca tggtaccgat ggtgatcccg atacccgagg
     4201 tgaaacctaa ggtgacggaa accggaatat actcaatcag gcgaccaaag cgtgccagac
     4261 ccatcagaat caaaaagatc cccgacagca aggtcgcaac cagcagtcct gccagtccaa
     4321 actgttgcga cacgggatag agaattacca caaatgccgc agtcggaccg gaaacgctaa
     4381 agcgtgaccc acccgtcaga gcaatgacaa tccccgcaac agctgcggta tataaaccgt
     4441 actggggtgc cacaccacta ccaatagcca acgccatcgc cagcgggata gcaataatcc
     4501 cgacggttat cccggcaatc aggtcacggg taaaccgtgc ggcagtatat ttttctttcc
     4561 agcaagcgtc gatcagagcg cggaaaggca tcacatgtga ggaaaatatt ttgttcacaa
     4621 taatgtttca tccgtgagcg catcatctgt caactaaatg gcaggtgaag gaggcatagg
     4681 tcatacaaat ggatattaca gacaaaaaaa cccgccgcag cgggtctttg agccgggttc
     4741 gattagtgtt cgaacatggc agagatcgat tcttcgttgc tgatacgacg aatcgcttcg
     4801 gccagcatac ctgacagggt cagagtacgc acgttcggca gtgatttgat ttcatcgctc
     4861 agcggaatgg tatcgcagac aacgacttca tcaattacag agttacgcag gttgttcgcc
     4921 gcgttgccag agaagatcgg gtgagtcgcg tacgcaaata cacgtttagc accacgttct
     4981 ttcagagctt cagcagcttt acacagcgta ccgccagtgt cgatcatatc atcgaccagt
     5041 acgcagtcac gacctgcaac gtcaccgatg atatgcatca cctgtgaaac gttcgcacgc
     5101 ggacgacgtt tgtcgatgat tgccatatcg gtatcgttca gcagcttagc gatagcgcgg
     5161 gcacgcacaa cgccgccgat gtccggagaa accacaattg ggttatccag attcagctgc
     5221 agcatgtctt ccagcaggat cgggctacca aatacgttat caaccggaac gtcgaagaaa
     5281 ccctgaatct gttcagcgtg cagatccact gtcagcacac ggtcaacacc gacgctggag
     5341 aggaagtctg caaccacttt cgcagtgatt ggtacacgag cggaacggac gcgacggtcc
     5401 tggcgcgcat agccaaagta ggggataaca gcggtgatac gacctgcgga agcacgacgc
     5461 agggcatcaa ccataacgac taattccatc aggttgtcgt tagtaggggc acaagtggac
     5521 tggatgatga aaatatcacc accgcgtaca ttttcattaa tttgtacgct gacttcgcca
     5581 tcgctaaagc gacctacagc ggcgtcgccg agtgaagtgt acaggcggtt ggcaatacgt
     5641 tgtgctagtt ccggggtggc gttaccagca aaaagcttca tatcaggcac gagaagaacc
     5701 tcaggcatgc gtccattggt ggaaagaatc tgccgaaaac tgtgcgggcc aggcatgatc
     5761 ctttccaggc ggtgtattaa agagcgcgat gcaacgtctg gaacaaggtg acgttgtcac
     5821 cgaaactcag cttgcccggc ttaaagcatg gctctgtgca atggggaaag attagcgcct
     5881 ttcgccacaa agccattgag ccattccggg gcttgctcta gcacctggcg ggcttcagac
     5941 tctgtatcaa attcagcaaa gacacaggcc cctgtcccag tcaggcgcga cggggcgtat
     6001 tctaacagcc aggaaagcac cgcatcaacc tcgcgaaaac gttttcttgc gataacctcg
     6061 caatcattgc tgaattcaca ttttagcaac gtttctattg acctttttgg cgtattgcgc
     6121 gggagttcag gatctttaaa aatcaccgga gtcggaatac ttacaccagg gtgcgccacc
     6181 agataccact tctctggcgg atccaccggc gttagtattt caccaacgcc ttcggcaaac
     6241 gcggcatgcc cccgaacaaa gacaggaaca tctgcgccca gcgtcagccc catttccgcc
     6301 agctcatcca tgcttagccc gcattgccag agatgattta atgccaccag gaccgtcgcg
     6361 gcattggatg aaccaccgcc gagaccgccg cccatcggca aacgcttgtc aatgctgata
     6421 ttcgcaccgc ttcccgtcgg aagacgcccg ctgtctgccg cagttttcat caacaatcgc
     6481 gctgcgcgaa cgatcaggtt atcttcatgt tccacgcctt caacgggcgt taacagacga
     6541 atatccccat cgtcacgaag ctcaatgctg atggtgtcgc cgtaatcaag aaactgaaac
     6601 agcgtttgca gcgtgtggta accatccgca cgctgaccgg taatgtataa aaacagatta
     6661 agttttgccg gagagggcca ctgtgtccgc attatttcac tatccagtta tccattttta
     6721 acttgatgcg ttgaccaccg tcggtgagtt ccatattggc tggcatcgca ggttgcgttt
     6781 tggtgtcata accaccataa acaaccttcc agtttttgcc attctggctg taggtaattt
     6841 cgctcaggcg gtactggtcg tccagtttgt agtcggttgc atcacccggt aaacctaaaa
     6901 tccactggcg caagctgttg agcggaattg gcattccggt caatttgcca atcatctctt
     6961 cggcgtcatc ggcggtataa cgctgacctt tattgtcgac taactgcacg ttacccggtt
     7021 gagcattcag ctccagttcc gtgctgccca atgggttagt gagcagcaga cggtagcgat
     7081 cctggccggt ttgctgccag aaaaagcggg cgtacacttt ttgttggtca gaaatataag
     7141 cgaacgcgcc gcgagtctga tactgattaa gattgcgcac gtcttgctga tgctgacgcc
     7201 attgtggcga atccgggctt ttgccaggac ctttgggcgt ggtaacggaa caggcagtga
     7261 gcacaagagc agccagcggt agcaggcgga taagacgaaa atcgggcagg ggcatagtga
     7321 tgacaagtcc ttgagatacg ttgcagttat aacccttaat gctagcgtta ccgtccgcta
     7381 tcgtctatgt tcaagttgtc ttaattgcca gaatctaacg gctttcggca attactccaa
     7441 aagggggcgc tctcttttat tgatcttacg catcctgtat gatgcaagca gactaaccct
     7501 atcaacgttg gtattatttc ccgcagacat gaccctttta gcactcggta tcaaccataa
     7561 aacggcacct gtatcgctgc gagaacgtgt atcgttttcg ccggataagc tcgatcaggc
     7621 tcttgacagc ctgcttgcgc agccgatggt gcagggcggc gtggtgctgt cgacgtgcaa
     7681 ccgcacggaa ctttatctta gcgttgaaga gcaggacaac ctgcaagagg cgttaatccg
     7741 ctggctttgc gattatcaca atcttaatga agaagatctg cgtaaaagcc tctactggca
     7801 tcaggataac gacgcggtta gccatttaat gcgtgttgcc agcggcctgg attcactggt
     7861 tctgggggag ccgcagatcc tcggtcaggt taaaaaagcg tttgccgatt cgcaaaaagg
     7921 tcatatgaag gccagcgaac tggaacgcat gttccagaaa tctttctctg tcgcgaaacg
     7981 cgttcgcact gaaacagata tcggtgccag cgctgtgtct gtcgcttttg cggcttgtac
     8041 gctggcgcgg cagatctttg aatcgctctc tacggtcaca gtgttgctgg taggcgcggg
     8101 cgaaactatc gagctggtgg cgcgtcatct gcgcgaacac aaagtacaga agatgattat
     8161 cgccaaccgc actcgcgaac gtgcccaaat tctggcagat gaagtcggcg cggaagtgat
     8221 tgccctgagt gatatcgacg aacgtctgcg cgaagccgat atcatcatca gttccaccgc
     8281 cagcccgtta ccgattatcg ggaaaggcat ggtggagcgc gcattaaaaa gccgtcgcaa
     8341 ccaaccaatg ctgttggtgg atattgccgt tccgcgcgat gttgagccgg aagttggcaa
     8401 actggcgaat gcttatcttt atagcgttga tgatctgcaa agcatcattt cgcacaacct
     8461 ggcgcagcgt aaagccgcag cggttgaggc ggaaactatt gtcgctcagg aaaccagcga
     8521 atttatggcg tggctgcgag cacaaagcgc cagcgaaacc attcgcgagt atcgcagcca
     8581 ggcagagcaa gttcgcgatg agttaaccgc caaagcgtta gcggcccttg agcagggcgg
     8641 cgacgcgcaa gccattatgc aggatctggc atggaaactg actaaccgct tgatccatgc
     8701 gccaacgaaa tcacttcaac aggccgcccg tgacggggat aacgaacgcc tgaatattct
     8761 gcgcgacagc ctcgggctgg agtagcagta catcattttc tttttttaca gggtgcattt
     8821 acgcctatga agccttctat cgttgccaaa ctggaagccc tgcatgaacg ccatgaagaa
     8881 gttcaggcgt tgctgggtga cgcgcaaact atcgccgacc aggaacgttt tcgcgcatta
     8941 tcacgcgaat atgcgcagtt aagtgatgtt tcgcgctgtt ttaccgactg gcaacaggtt
     9001 caggaagata tcgaaaccgc acagatgatg ctcgatgatc ctgaaatgcg tgagatggcg
     9061 caggatgaac tgcgcgaagc taaagaaaaa agcgagcaac tggaacagca attacaggtt
     9121 ctgttactgc caaaagatcc tgatgacgaa cgtaacgcct tcctcgaagt ccgagccgga
     9181 accggcggcg acgaagcggc gctgttcgcg ggcgatctgt tccgtatgta cagccgttat
     9241 gccgaagccc gccgctggcg ggtagaaatc atgagcgcca gcgagggtga acatggtggt
     9301 tataaagaga tcatcgccaa aattagcggt gatggtgtgt atggtcgtct gaaatttgaa
     9361 tccggcggtc atcgcgtgca acgtgttcct gctacggaat cgcagggtcg tattcatact
     9421 tctgcttgta ccgttgcggt aatgccagaa ctgcctgacg cagaactgcc ggacatcaac
     9481 ccagcagatt tacgcattga tactttccgc tcgtcagggg cgggtggtca gcacgttaac
     9541 accaccgatt cggcaattcg tattactcac ttgccgaccg ggattgttgt tgaatgtcag
     9601 gacgaacgtt cacaacataa aaacaaagct aaagcacttt ctgttctcgg tgctcgcatc
     9661 cacgctgctg aaatggcaaa acgccaacag gccgaagcgt ctacccgtcg taacctgctg
     9721 gggagtggcg atcgcagcga ccgtaaccgt acttacaact tcccgcaggg gcgcgttacc
     9781 gatcaccgca tcaacctgac gctctaccgc ctggatgaag tgatggaagg taagctggat
     9841 atgctgattg aaccgattat ccaggaacat caggccgacc aactggcggc gttgtccgag
     9901 caggaataat ggaatatcaa cactggttac gtgaagcaat aagccaactt caggcgagcg
     9961 aaagcccgcg gcgtgatgct gaaatcctgc tggagcatgt taccggcaga gggcgtactt
    10021 ttattctcgc ctttggtgaa acgcagctga ctgacgaaca atgtcagcaa cttgatgcgc
    10081 tactgacacg tcgtcgcgat ggtgaaccca ttgctcattt aaccggggtg cgagaattct
    10141 ggtcgttgcc gttatttgtt tcgccagcga ccttaattcc gcgcccggat acggagtgtc
    10201 tggtggagca ggcactggcg cggttgcctg aacaaccttg ccgtattctc gatctcggga
    10261 cgggtaccgg ggcgattgcg cttgcgctgg ctagcgagcg cccggactgc gaaattatcg
    10321 ctgtagatcg tatgcctgat gctgtctccc tggcacaacg taatgcccag catctggcga
    10381 tcaaaaatat ccacattctg caaagcgact ggtttagcgc gctagccggg cagcagtttg
    10441 cgatgattgt cagcaatccg ccgtatattg acgagcagga ccctcatctt caacaaggcg
    10501 atgtccgctt tgagccgctc actgcgctgg ttgcggcaga cagtggaatg gcagacatcg
    10561 tgcatatcat cgaacagtcg cgtaacgcgc tggtatccgg cggctttctg cttctggaac
    10621 atggctggca gcagggcgaa gcggtgcgac aagcatttat cctcgcgggg tatcatgacg
    10681 tcgaaacctg ccgtgactat ggtgataacg agcgcgtaac gctcggccgc tattatcaat
    10741 gacaagtttt tctacactgc ttagtgttca tcttattagt atcgcgcttt ctgttgggct
    10801 attaacctta cgtttctggc tacgttatca gaagcatcca caggcatttg ctcgctggac
    10861 gcgcattgtg ccgccggttg tcgatacgct gttactgtta agcggcattg cgttgatggc
    10921 taaagcgcac atcctgccat tttccgggca ggcacagtgg ctgactgaaa agctgtttgg
    10981 agttatcatt tatatcgttt tgggttttat tgcactcgat tatcgtcgta tgcacagtca
    11041 gcaggcgcgc attattgcct tcccgctggc gttggtggtg ctgtacatca tcattaaact
    11101 cgccaccaca aaagtaccgt tactggggta agtcatgaga tcgttagctg atttcgaatt
    11161 taataaagcg ccattgtgcg aaggcatgat cctggcttgc gaagcaatcc gccgcgattt
    11221 tccctcgcaa gatgtttacg acgaactgga gcgtctcgtt agtctggcga aggaagaaat
    11281 cagccagctt ctgcctttag aagagcagtt ggaaaaactg atcgcgctgt tttacggcga
    11341 ctggggattt aaagcctcac gcggtgttta tcgtctttcc gatgcattat ggctggacca
    11401 ggtgttaaag aatcgacagg gcagtgcggt atcattaggt gcggttttat tatgggtcgc
    11461 gaatcgtctc gatttgccgc tgctgccggt gattttccct acgcagctga tattgcgcat
    11521 tgaatgtccg gatggcgaaa tttggctgat taatcctttt aacggtgaat cgttaagcga
    11581 acatatgctg gacgtatggt taaagggaaa tatcagcccg tcggcggaac tgttttatga
    11641 agaccttgat gaagctgata acattgaggt aatccgcaaa ttgctggata cactcaaagc
    11701 ctcgttgatg gaagaaaatc agatggagct ggcgttacgc accagcgaag ctttattaca
    11761 attcaaccct gaagatccct atgaaattcg cgatcgcggg ttgatttatg cgcaactgga
    11821 ttgcgaacac gttgcgttga acgatttaag ttatttcgtt gaacagtgtc cggaagaccc
    11881 gatcagcgaa atgatccgtg cgcaaataaa taacatcgcg cataaacata ttgtgctgca
    11941 ttaattaatc gacattttac tcaagattaa ggcgatccta tgaaacaaaa agtggttagc
    12001 attggcgaca tcaacgtagc aaatgacctg ccgttcgtac tgtttggcgg tatgaacgtg
    12061 ttggaatctc gcgatctggc gatgcgcatt tgcgagcact acgtaactgt gacccagaaa
    12121 ctgggtatcc cttacgtgtt caaagcctct tttgacaaag ccaaccgctc ctccatccac
    12181 tcttatcgtg gaccgggcct ggaagaaggg atgaaaatct tccaggagtt gaagcagact
    12241 tttggcgtga aaattatcac cgacgttcac gaaccaagtc aggcacagcc cgttgctgat
    12301 gtcgtggatg tgattcagtt gccggcgttt cttgctcgcc agactgacct ggttgaagcc
    12361 atggcgaaaa ccggtgcggt aattaacgtc aagaaaccac agtttgtcag cccgggacag
    12421 atgggtaata tcgttgataa attcaaagaa ggcggcaacg aaaaagtgat tctttgcgat
    12481 cgcggtgcta acttcggcta tgacaacctg gttgtcgata tgctgggctt cagcattatg
    12541 aagaaagtgt ctggtaactc gccggtgatt ttcgacgtga cccacgcact gcaatgccgc
    12601 gatccgtttg gcgcagcttc cggtggtcgt cgtgctcagg tggctgagct ggcacgagcc
    12661 ggtatggcgg taggtctggc ggggctgttt attgaagcgc atccggatcc ggaacatgcg
    12721 aaatgtgatg gtccatccgc gctgccgctg gctaaactgg aaccgttcct caagcagatg
    12781 aaagcgattg atgatctggt gaaaggtttc gaagaactgg ataccagcaa gtaatctttt
    12841 ttgcttgaaa aataaagtat tagcgttctg cgttaagact tttttcatgg gtgccggata
    12901 caaaaaaggc cgcaggctgt tacccctgcg gccggtttcg ggcgcatatt gccatcacgg
    12961 cagcctgacg cccgttttca ccttacttcc ggttacgcca ccagctgaca atcgctgcgg
    13021 taataattcc cgccaggatc ggtgctgcca ggtcgtgcca gaaaatcatg gcaaactgcg
    13081 cgagcgtcat atagccgcct tgttgtaatg acaacatttt gcggctattc ttgaattgtt
    13141 ctggttcaag attagccccc gttctgttgt caggttgtac ctctcaacgt gcgggggttt
    13201 tctctttcca gcaaccaatg ccaccaggga taaagccccc gcaacattgc gcctcaccgg
    13261 ataacgccgg cttggtgtgg atactacgac tcaattcatc ttcacttcat ccctgaaatg
    13321 tttgcaatga agagtgcatt ccggtttttc aacagctgtt acagtcattt catgagtgct
    13381 ctggatgagg cttccagctc gggttgccaa tatttacttg tggaagtgat aaagacaaaa
    13441 atggccgcag gctgttaccc ctgcggccgg tttcgggcgc atattgccat cacggcagcc
    13501 tgacgcccgt tttcacctta cttccggtta cgccaccagc cgacaatcgc tgcggtaata
    13561 attcccgcca ggatcggtgc cgccaggtcg tgccagaaag tcatggcaaa ctgcgcgagc
    13621 gtcatatagc cgccttgttg taatgacaac attttgcggc tattcttgaa gtgtctggtt
    13681 tcaagattag cccccgttct gttgtcaggt tttacctctc aacgtgcggg ggttttctct
    13741 ttccagcaac caatgccacc agggataaag cccccgcaac attgcgcctc accggataat
    13801 tccggcttgg tgtggatact acgtctcaat tcatcttcac ttcatccctg aaatgtttgc
    13861 aataaagagt acattccggc ttttcaacag ctgttgcagt cgtttcatga gtgctctgga
    13921 tgatgcttcc agctcgggtt gccaatattt acttgtggaa gagataaaga caaaaatggc
    13981 cgcaggctgt tacccctgcg gccggtttcg ggcgcatatt gccatcacgg cagcctgacg
    14041 cccgttttca ccttacttcc ggttacgcca ccagctgaca atcgctgcgg taataattcc
    14101 cgccaggatc ggtgctgcca ggtcgtgcca gaaaatcatg gcaaactgcg cgagcgtcat
    14161 atagccgcct tgttgtaatg acaacatttt gcggctattc ttgaagtgtc tggtttcaag
    14221 attagccccc gttttgttgt caggttttac ctctcaacgt gcgggggttt tctctttcca
    14281 gcaaccaatg ccaccaggga taaagccccg caacattgcg cctcaccgga taacgccggc
    14341 ttggtgtgga tactacgtcg caattcatct tcacttcatc cctgaaatgt ttgcaatgaa
    14401 gagtacattc cggcttttca acagctgttg cagtggtttc gtgcagggtg tggtacaggc
    14461 tcgcaattct gattaacgac ctgtccaggt agtatgaaga aatacaataa gcaggaattt
    14521 atattatctc ccccgattac cgtcatcgga ggagatataa ctgtcaggca aatatcgtca
    14581 tcaaataggc ggcaaacagt gccagatgcg ctgcgccatt gagcacgtta gtacgtccgg
    14641 tggagaagga gatatggcac agcactaaag aggccaccat caccaccatt tctggcgcac
    14701 caagtgcaaa ctgcaattcg ttacccgtca taaaggcaat tagcgtgacg acaggtacgg
    14761 taagcgaaat ggttgctaac actgaaccaa agaacagatt catcgcgcgc tgaacctggt
    14821 tgttcaacac tgcttttaat gcacctaaac cttccggcga cagaatcaac agtgccacca
    14881 ggaagccagt aaaggcgaca ggggcattca tgctgtcgag caatgtctcc agcgagctgg
    14941 cgttcatttt ggtcaccgca ataacggcaa tcagatggat aatcaaccag atagcatgcc
    15001 acaggctgct atgggcagac ggtttaccgt gatgcgggtc gtcatcatca ctgtcatctt
    15061 cgtgctcgta gacaaacaaa ctttgatgcg ttttggtctg gatcagcaaa aatacgccat
    15121 acattgccgc agaaattaat gctaccagta acgcctgacc ggttgaaaaa ttcgccgcag
    15181 gcagagccat tggaaatacc agtacgatta tcgccagggg gaacagcgca attaaatact
    15241 gcttgatacc aaacagattc atatattggg tggcaaactt acgaccgccc aacaataatg
    15301 aaaagccaac cagcccaccg gtaacaatca taatgattga atagagcgta tcacgcatta
    15361 gcgttggcgc ggcgtcgccg gttgccatta aagctgaaat caaactgact tcaagaataa
    15421 ccactgaaag gctaagaata agcgaaccgt aaggttctcc caggcgatgg gctaatacgt
    15481 ccgcatgacg gacaacacta aaggcgctac ttaaaatacc aataagcgca agaagattga
    15541 tggcaatgac cactggtagt gtctggctgc ttccccacag gaacagcact accagcgcca
    15601 gaaccgggaa aataagcgaa gtctccttgt ggcgggtttt taccgcctct tgagcatttg
    15661 acattatggt tatccctttg cagatgaatt tatcgaaaat gtaaaaaata ggtaggaaaa
    15721 ataacagaaa gtgtctggat atcggtaaca ttttacgaat ttttaccccg ctgtcgattt
    15781 tttactcatt ggggcataaa aataagtatt acgtttagac aatgtttgtt ttagcgtttc
    15841 ttaagaagag tctgacctga aaattcttat gttttggcaa gagtagatat tgttgaccac
    15901 acttaatgtt caactttgta aaaggagtca acgatgccgt ataaaacgaa aagcgatctg
    15961 ccggaaagcg taaagcacgt tctaccgtct catgcccagg atatctataa agaagcgttc
    16021 aacagcgcat gggatcaata taaagataaa gaagatcggc gtgatgacgc cagtcgcgaa
    16081 gaaaccgcgc ataaagtggc ctgggctgct gtgaagcatg aatatgccaa aggggatgat
    16141 gataaatggc ataaaaaatc gtaaaaccgg tcgcttagtt aaagctattc gtgcggtgtt
    16201 gccttgcaag tggtccgtgg attgcatatt gtcccgttag tggtttcaaa atgagcagta
    16261 aaaatgtccg gaagacacca aaaagttgtc gcagggaagt atgcagtggc ggaggtgtaa
    16321 ggtgataacg cgtgatttct tgatgaatgc cgattgtaaa acggcatttg gtgccattga
    16381 agaatcactc ttatggtcag cagaacaacg ggcggcttcg ctggcggcga cgctggcttg
    16441 tcgacctgat gagggaccgg tgtggatctt cggctatgga tcgttgatgt ggaatccggc
    16501 actggagttt accgaatcgt gcaccggtac actggttgga tggcatcgcg cattttgcct
    16561 gcgcctgacc gccgggcgcg ggactgcgca ccagccggga cggatgcttg cactgaaaga
    16621 gggcggacgc accacaggcg tcgcctatcg actgccagaa gagacgctgg agcaggaact
    16681 aaccctgttg tggaagcgag agatgattac cggctgttat ctgccaacct ggtgtcagct
    16741 tgatcttgat gatggacgca cagtaaacgc cattgtgttt attatggacc cgcgacatcc
    16801 agaatatgaa tctgatactc gcgctcaggt catcgcgccg ttgattgcgg cggcgagcgg
    16861 tccgctggga accaacgcac aatacctgtt ttcactggaa caggagctta tcaaactggg
    16921 aatgcaggac gatgggctga atgatttgct ggtatcggta aaaaaactgc tggcggagaa
    16981 ttttccggat ggtgtgttac gtccgggatt cgcctgagta aacttcccgc atagtggggc
    17041 gtcagacgcc ccctcaaaca ttaaaatgtg agcactttat cggctgacag cgtccattgc
    17101 gccagttcca caagagtacc gatttccacc ccatcaatca gaggaagtgt actaatcccg
    17161 cgcccgtcgg tacaggtttt gcacaatttc accggtacat tctgagcggt aaggatctcc
    17221 agcatttgct gaatgttgta gccttcccct ggtttttgcc cgcgcaaccc ggctgtgacc
    17281 gcatcagaca tgaggaacag acgcagatcc agattgctct cctgctctcg taacgcaatg
    17341 gccagccgca agctgttaaa caaggattcg ctcccgtaag gtgcgccatt ggcaacgatc
    17401 acgatttttt gcattattta ctcctgtatt cagggaatta gacactcatc ttctatctta
    17461 ctgcttctgc agcgtctgac caatcggtca catttttaag gattttcctg aaagcgcgag
    17521 aaaatacgac aaaagttgcc agtaatcgtt attctttaag gctatggttt ttcattatta
    17581 ccggaagtta ccgacgtttt gagccgtttc gttcctcgca ttatcccgtt ttatttactc
    17641 ttgcttgtag caggcggtac agctaacgca caatctacct tcgagcaaaa agcggcaaat
    17701 ccctttgata ataacaatga tggtctgccg gatttaggca tggctcccga aaatcatgat
    17761 ggggaaaaac actttgctga aattgtgaaa gatttcggcg aaaccagtat gaatgataac
    17821 gggctggata ctggcgagca ggcaaaagct ttcgcattgg gaaaagtccg cgacgcgctt
    17881 agtcaacagg ttaatcagca cgtagagtcc tggctatcac cgtggggaaa tgccagtgtt
    17941 gacgtcaaag tggataacga aggacatttc accggcagtc gtggaagctg gtttgtgccg
    18001 ttacaagata atgatcgtta tctcacctgg agccagcttg gtcttactca gcaggataat
    18061 gggttggtga gcaatgtggg cgttgggcaa cgctgggcgc gcggcaactg gctggtgggt
    18121 tataacactt tttatgacaa cttgctggac gaaaatcttc agcgagcggg ctttggtgcc
    18181 gaagcgtggg gcgaatattt gcgattatcg gcaaactttt atcagccgtt tgctgcatgg
    18241 catgaacaga cagccacgca ggaacaacgg atggcgcgcg ggtacgacct gacagctcgg
    18301 atgcgcatgc cgttctatca acacctcaat accagtgtca gcctagaaca gtattttggt
    18361 gatcgtgttg atttgtttaa ctctggtacg ggttatcaca atcccgtcgc gttgagtctg
    18421 ggattaaatt acacccctgt gccattagtc actgtgacgg cccagcataa acagggtgaa
    18481 agtggcgaaa atcaaaataa cctcgggctg aatcttaatt accgctttgg tgtaccgctc
    18541 aaaaaacaac tttctgcggg cgaggttgcc gaaagtcagt cgttacgtgg tagtcgctat
    18601 gacaatccgc agcgaaataa tctaccgact cttgagtacc gacagcgaaa aacgttaacg
    18661 gtgtttctgg cgacaccgcc gtgggatcta aaacctggcg aaacagtgcc gctgaaatta
    18721 caaatccgca gtcgttacgg tattcggcaa ctgatttggc agggcgatac gcagatatta
    18781 agtttgacgc cgggcgcaca agccaacagc gcggagggct ggacgctgat catgcctgac
    18841 tggcagaacg gggaaggggc aagcaatcac tggcgattgt ctgtggtggt ggaagataac
    18901 caggggcagc gtgtctcctc caatgagatc acgctaacgc ttgtcgaacc gttcgatgca
    18961 ttgtcaaacg acgaactgcg ctgggaaccg taatcagaaa atgcgctcct gatgcaccca
    19021 taccgctgct tccacgcgag acttgagctt cattttcttc agcatgtgct tgacgtgcac
    19081 ttttactgtg ctttcggtga tatccaggcg gcgggcaatc atcttgttcg gcaaaccctg
    19141 ggcaatcagc ttgagaatat cgcgctcgcg tggggttaac tggttaacat cgcgctcagt
    19201 agtggcacgg ttagcgcgca agctggcggc cagaacaggc gttaatgctt cgcttaatac
    19261 catttcgcca gcagctgcct gatgcaatgc tttcagcaga tcttccggtt ccatatcttt
    19321 taacagatag ccatccgcgc cgcgtttcag tgcggtgacc acatcttctt catggttaga
    19381 gacgctgaat accacaatgc gccctgagag ggacttttcg cgcagtttat ccagcgtttc
    19441 cagaccgttc atgccgggca tattgagatc taacaggatc agatcgggat caagagactc
    19501 cgccagttca ataccctgtt cgccattact cgcttcgcca accacggtga tatctggtgc
    19561 catactgata agctgtttta cgccagttcg cagcatcggg tgatcgtcaa tcagcaggat
    19621 agtagccggt tcctgattac tcatgggtat ctccttggac gtctgtgaaa gttttttcgg
    19681 gaataaaggt gaccaccact tcggtgccac ctgattcacg acggcggacg cggcaatcgc
    19741 ctcgtaaact ttgcgcacga tcgcgcatta ttatcatgcc gtagtgattg ctgcggatgg
    19801 cattttcagg cacgccgcag ccgttatcct ggacggtcag tttgacctga ttatcgtttt
    19861 gcgccaccgt caccacgact tcactcgctt gcgaatgttt gagggcgtta cttaatgcct
    19921 cacgggcaat ttgcaacaag tggattgcct gatgcgaagg caccaggcga ggcggcaatt
    19981 gataatccag cttcaccggg aagccaaatt tggcgctgta ctcttcgcaa ctcgcctcca
    20041 gcgccggacg taatccaggc tcggtgagct gcaagcggaa tgtggtgagc aattcacgca
    20101 actgcgccca ggatgcattc agttcgttac ggatctgact taacagttcg cggctgcttt
    20161 ctggcagcgc atcgccctgc atctgtaaac aactcacctg catcttcatg caagagagag
    20221 attgggcaat agaatcatgc agttcgcgcg caatggtggc acgctcttcc atcacgatca
    20281 actgttgctg acgttcctga tggcgatcca gcgccagcgt ggcggtgagt tgttcaacca
    20341 gggtatccac cagttgttgt tgatcatggc taagatgacg cccctgcggc agggtcgcca
    20401 gcaaaatacc gtactgcgta tgagagtcag ccagccgcca cttcagggtc gtgccgcgat
    20461 caccaacggg taatacgccg cgcgggcaga gctggcagcc tttatcatca caagtcatat
    20521 ctggctggca ggtaaactcc tgatgattct cttcatcatc agtgtcatac acccgcaatt
    20581 cgatatcacg tagcagggtt aaattctgta agccgttgag tacaggtgac aggcgttcac
    20641 acagcggggc gcgggaatgc aaacggcggt tagcctgcca taaaaaagag aggatctgat
    20701 ttttatgctc cagcccggcg gttttctcct gaacccgctg ctcaagtacg gcataacttt
    20761 cggccagttc tgcagacata ttgttcaacg cagttccaag catcgccatt tcgttgcgcc
    20821 cgctgatgtt tgcgcgttgg gtaaaatcgc gatgactgac ggcactcgcc attgccagca
    20881 gttgccgcca cggttgtagc agtcgcgccc gcaaccagat aatagtgaac accagtaaaa
    20941 gtgccataaa taccgccatt acccgatgga ccagtaccac tgtctcgatg cgcatttccg
    21001 tggtgcggtc aaaaccagat accagttgat caagcccggc aacaaactgg ctgacatccg
    21061 ctgacaccgt ttctcggttt tgtgcacgca tcagcgcagg gatcagttca ttacgccagt
    21121 aatcttgtaa accctgtaat tgcgccagtt gtccgtctcg ttctgctgct cgagtcaact
    21181 cggcgctaaa tgccgtttgt tccatctctt taattaaggg cttgtctttc tcgcttaatg
    21241 gcactgccgc caacagacgg taactttgca tgcgcagcga tcccgctttg ttgatcgcat
    21301 gggcgctgcc ctgaacgcct tgcaccagcc agccagaaac cgccatccct gccagtccaa
    21361 tagcagtaga aagcaacaca ataagcgcaa cctgattaac cagggtgagc ggagagagac
    21421 aacgtttaag catgtaaacc tcttccttca ggctttaaat gagcaataac cttaatgaat
    21481 gtgacgatac attctggaat ggcagtattc tcggctattg gctgaagtat acccataccc
    21541 ggaaagagtt actccttatt tgccgtgtgg ttagtcgctt tacatcggta agggtaggga
    21601 ttttacagca ccgtgaaaaa tctcataatt tttatgaagt cactgtactc actatgggta
    21661 atgataaata tcaatgatag ataaagttat cttatcgttt gatttacatc aaattgcctt
    21721 tagctacaga cactaaggtg gcagacatcg aaacgagtat cagaggtgtc tatgagtcac
    21781 tcatccgccc ccgaaagggc tactggagct gtcattacag attggcgacc ggaagatcct
    21841 gcgttctggc aacaacgcgg tcaacgtatt gccagccgca acctgtggat ttccgttccc
    21901 tgtctgctgc tggcgttttg cgtatggatg ttgttcagcg ctgttgcggt gaacctaccg
    21961 aaagtcggct ttaattttac gaccgatcag ctatttatgt tgactgcgct gccttcggtt
    22021 tctggcgcgt tattacgtgt tccatactcc tttatggttc ctatcttcgg tggtcgtcgc
    22081 tggacggcgt tcagcaccgg tattctgatt attccttgcg tctggctggg ttttgccgtg
    22141 caggatacct ccacgcctta tagcgtcttc atcatcatct ctctgctatg cggctttgct
    22201 ggcgcgaact tcgcatccag tatggcaaac atcagcttct tctttccgaa acagaagcag
    22261 ggtggcgcgc tgggtctgaa tggtggtctg ggaaacatgg gcgtcagcgt catgcagttg
    22321 gttgctccgc tggtggtatc actgtcgatt ttcgcagtat ttggtagcca gggcgtcaaa
    22381 cagccggatg ggactgagct gtatctggcg aatgcgtcct ggatatgggt gccgttcctt
    22441 gccatcttca ccattgcggc gtggtttggc atgaacgatc ttgctacctc gaaagcctcc
    22501 atcaaggagc agttgccggt actcaaacgg ggtcatctgt ggattatgag cctgctgtat
    22561 ctggcaacct tcggctcctt catcggcttc tccgcgggct tcgcaatgct gtcaaaaacg
    22621 cagttcccgg atgttcagat tctgcaatac gctttcttcg ggccgtttat tggtgcgctg
    22681 gcgcgttctg caggtggtgc attatctgac cgtctgggcg gaactcgtgt cacgctggtg
    22741 aactttattc tgatggcgat tttcagcggc ctgctgttcc tgaccttacc gactgacggg
    22801 cagggcggaa gcttcatggc gttcttcgcg gtcttcctgg cgctgttcct gacagctggg
    22861 ctgggtagtg gttccacttt ccagatgatt tcagtgatct tccgtaaact gacaatggat
    22921 cgcgtgaaag cagaaggggg ttctgacgaa cgtgcgatgc gtgaagcggc aaccgacacg
    22981 gcggcggcgc tgggtttcat ctctgcgatt ggcgcgattg gtggcttctt tatcccgaaa
    23041 gcgtttggta gctcgctggc attaacgggt tcgccagtcg gcgcaatgaa ggtatttttg
    23101 attttctata tcgcctgcgt agtgattacc tgggcggtat atggtcggca ttctaaaaaa
    23161 taaaccgtta ctcgtcatac ttcgggttac atgtgctgcg gctgcgttca ttcaccccag
    23221 tcacttactt tagtaagctc ctgggattca ttcacttgcc gccttcctgt aaaccgaatt
    23281 atatagagta aaatatttga ttatcctttg cgcggcatga tgtcgcgctt tttttatgcg
    23341 t
//
LOCUS       DAPOAV010000070        23340 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.070, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000070 DAPOAV010000000
VERSION     DAPOAV010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23340
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.070"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(253..597)
                     /locus_tag="RN951_003135"
     CDS             complement(253..597)
                     /locus_tag="RN951_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416323.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDX2528101.1"
                     /translation="MTIVRIDAEARWSDVVIHNNTLYYTGVPENLDADAFEQTANTLA
                     QIDAVLEKQGSNKSSILDATIFLADKNDFAAMNKAWDAWVVAGHAPVRCTVQAGLMNP
                     KYKVEIKIVAAV"
     gene            729..2639
                     /locus_tag="RN951_003136"
     CDS             729..2639
                     /locus_tag="RN951_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HDX2528102.1"
                     /translation="MTDDFAPDGQLAKAIPGFKPREPQRQMAVAVTQAIEKGQPLVVE
                     AGTGTGKTYAYLAPALRAKKKVIISTGSKALQDQLYSRDLPTVSKALKYTGNVALLKG
                     RSNYLCLERLEQQALAGGDLPVQILSDVILLRSWSNQTVDGDISTCVSVAEDSQAWPL
                     VTSTNDNCLGSDCPMYKDCFVVKARKKAMDADVVVVNHHLFLADMVVKESGFGELIPE
                     ADVMIFDEAHQLPDIASQYFGQSLSSRQLLDLAKDITIAYRTELKDTQQLQKCADRLA
                     QSAQDFRLQLGEPGYRGNLRELLANPQIQRAFLLLDDTLELCYDVAKLSLGRSALLDA
                     AFERATLYRTRLKRLKEINQPGYSYWYECTSRHFTLALTPLSVADKFKELMAQKPGSW
                     IFTSATLSVNDDLHHFTSRLGIEQAESLLLPSPFDYSRQALLCVPRNLPQTNQPGSAR
                     QLAAMLRPIIEANNGRCFMLCTSHAMMRDLAEQFRATMTLPVLLQGETSKGQLLQQFV
                     SAGNALLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFD
                     EVQLPDAVITLKQGVGRLIRDADDRGVLVICDNRLVMRPYGATFLASLPPAPRTRDIA
                     RAVRFLAIPSSR"
     gene            2697..3392
                     /gene="tsaB"
                     /locus_tag="RN951_003137"
     CDS             2697..3392
                     /gene="tsaB"
                     /locus_tag="RN951_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HDX2528103.1"
                     /translation="MRILAIDTATEACSVALWNDGTVNAHFELCPREHTQRILPMVQD
                     ILTTSGTSLTDINALAYGRGPGSFTGVRIGIGIAQGLALGAELPMIGVSTLMTMAQGA
                     WRKNGATRVLAAIDARMGEVYWAEYQRDENGIWHGEETEAVLKPEIVHERMQQLSGEW
                     VTVGTGWQAWPDLGKESGLVLRDGEVLLPAAEDMLPIACQMFAEGKTVAVEHAEPVYL
                     RNNVAWKKLPGKE"
     gene            3432..4013
                     /gene="yeaY"
                     /locus_tag="RN951_003138"
     CDS             3432..4013
                     /gene="yeaY"
                     /locus_tag="RN951_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Slp family lipoprotein YeaY"
                     /protein_id="HDX2528104.1"
                     /translation="MAVQKNVIKGILAGTFALMLSGCVTVPDAIKGSSPTPQQDLVRV
                     MSAPQLYVGQEARFGGKVVAVQNQQGKTRLEIATVPLDSGARPTLGEPSRGRIYADVN
                     GFLDPVDFRGQLVTVVGPITGAVDGKIGNTPYKFMVMQVTGYKRWHLTQQVIMPPQPI
                     DPWFYGGRGWPYGYGGWGWYNPGPARVQTVVTE"
     gene            4219..5904
                     /gene="fadD"
                     /locus_tag="RN951_003139"
     CDS             4219..5904
                     /gene="fadD"
                     /locus_tag="RN951_003139"
                     /EC_number="6.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain-fatty-acid--CoA ligase FadD"
                     /protein_id="HDX2528105.1"
                     /translation="MKKVWLNRYPADVPTEINPDRYQSLVDMFEQSVARYADQPAFVN
                     MGEVMTFRKLEERSRAFAAYLQQGLGLKKGDRVALMMPNLLQYPVALFGILRAGMIVV
                     NVNPLYTPRELEHQLNDSGASAIVIVSNFAHTLEKVVDKTAVQHVILTRMGDQLSTAK
                     GTVVNFVVKYIKRLVPKYHLPDAISFRSALHNGYRMQYVKPELVPEDLAFLQYTGGTT
                     GVAKGAMLTHRNMLANLEQVNATYGPLLHPGKELVVTALPLYHIFALTINCLLFIELG
                     GQNLLITNPRDIPGLVKELAKYPFTAITGVNTLFNALLNNKEFQQLDFSSLHLSAGGG
                     MPVQQVVAERWVKLTGQYLLEGYGLTECAPLVSVNPYDIDYHSGSIGLPVPSTEAKLV
                     DDDDNEVPPGQPGELCVKGPQVMLGYWQRPDATDEIIKNGWLHTGDIAVMDEEGFLRI
                     VDRKKDMILVSGFNVYPNEIEDVVMQHPGVQEVAAVGVPSGSSGEAVKIFVVKKDPSL
                     TEESLVTFCRRQLTGYKVPKLVEFRDELPKSNVGKILRRELRDEARGKVDNKA"
     gene            5986..7101
                     /gene="rnd"
                     /locus_tag="RN951_003140"
     CDS             5986..7101
                     /gene="rnd"
                     /locus_tag="RN951_003140"
                     /EC_number="3.1.13.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707318.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease D"
                     /protein_id="HDX2528106.1"
                     /translation="MITTDDALASLCEAVRAFPAIALDTEFVRTRTYYPQLGLIQLFD
                     GEHLALIDPLGITDWSPLKAILRDPSITKFLHAGSEDLEVFLNVFGELPQPLIDTQIL
                     AAFCGRPMSWGFASMVEEYSGVTLDKSESRTDWLARPLTERQCEYAAADVWYLLPITA
                     KLMVETEASGWLPAALDECRLMQMRRQEVVAPEDAWRDITNAWQLRTRQLACLQLLAD
                     WRLRKARERDLAVNFVVREEHLWSVARYMPGSLGELDSLGLSGSEIRFHGKTLLALVE
                     KAQTLPEDALPQPMLNLMDMPGYRKAFKAIKSLITDVSETHKISAELLASRRQINQLL
                     NWHWKLKPQNNLPELISGWRGELMAEALHNLLQEYPQ"
     gene            complement(7155..8120)
                     /gene="yeaX"
                     /locus_tag="RN951_003141"
     CDS             complement(7155..8120)
                     /gene="yeaX"
                     /locus_tag="RN951_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine monooxygenase subunit YeaX"
                     /protein_id="HDX2528107.1"
                     /translation="MSDYQMFEVQVSQVEPLTEQVKRFTLVATDGKPLPAFTGGSHVI
                     VQMSDGDNQYSNAYSLLSSPHDTSCYQIAVRLEENSRGGSRFLHQQVKVGDRLTISTP
                     NNLFALIPSARKHLFIAGGIGITPFLSHMAELQHSDVDWQLHYCSRNPESCAFRDELV
                     QHPQAEKVHLHHSSTGTRLELARLLADIEPGTHVYTCGPEALIEAVRSEAARLDIAAD
                     TLHFEQFAIEDKTGDAFTLVLARSGKEFVVPEEMTILQVIENNKAAKVECLCREGVCG
                     TCETAILEGEADHRDQYFSDEERASQQSMLICCSRAKGKRLVLDL"
     gene            complement(8176..9300)
                     /gene="yeaW"
                     /locus_tag="RN951_003142"
     CDS             complement(8176..9300)
                     /gene="yeaW"
                     /locus_tag="RN951_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine monooxygenase subunit YeaW"
                     /protein_id="HDX2528108.1"
                     /translation="MSNLSPDFVLPENFCANPQEAWTIPARFYTDQNAFEHEKENVFA
                     KSWICVAHSSELANANDYVTREIIGESIVLVRGRDKVLRAFYNVCPHRGHQLLSGEGK
                     AKNVITCPYHAWAFKLDGNLAHARNCENVANFDSDKAQLVPVRLEEYAGFVFINMDPN
                     ATSVEDQLPGLGAKVLEACPEVHDLKLAARFTTRTPANWKNIVDNYLECYHCGPAHPG
                     FSDSVQVDRYWHTMHGNWTLQYGFAKPSEQSFKFEEGTDAAFHGFWLWPCTMLNVTPI
                     KGMMTVIYEFPVDSETTLQNYDIYFTNEELTDEQKSLIEWYRDVFRPEDLRLVESVQK
                     GLKSRGYRGQGRIMADSSGSGISEHGIAHFHNLLAQVFKD"
     gene            complement(9332..10813)
                     /gene="yeaV"
                     /locus_tag="RN951_003143"
                     /pseudo
     CDS             complement(9332..10813)
                     /gene="yeaV"
                     /locus_tag="RN951_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310537.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BCCT family transporter YeaV"
     gene            complement(10968..12053)
                     /gene="dmlA"
                     /locus_tag="RN951_003144"
     CDS             complement(10968..12053)
                     /gene="dmlA"
                     /locus_tag="RN951_003144"
                     /EC_number="1.1.1.83"
                     /EC_number="1.1.1.85"
                     /EC_number="1.1.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional
                     D-malate/3-isopropylmalate/tartarate dehydrogenase"
                     /protein_id="HDX2528109.1"
                     /translation="MMKTMRIAAIPGDGIGKEVLPEGIRVLQAAAERWGFALSFEQME
                     WASCEYYSHHGKMMPDDWHEQLSRFDAIYFGAVGWPDTVPDHISLWGSLLKFRREFDQ
                     YVNLRPVRLFPGVPCPLAGKQPGDIDFYVVRENTEGEYSSLGGRVNEGTEHEVVIQES
                     VFTRRGVDRILRYAFELAQSRPRKTLTSATKSNGLAISMPYWDERVEAMAENYPEIRW
                     DKQHIDILCARFVMQPERFDVVVASNLFGDILSDLGPACTGTIGIAPSANLNPERTFP
                     SLFEPVHGSAPDIYGKNIANPIATIWAGAMMLDFLGNGDERFQQAHNGILAAIEEVIA
                     HGPKTPDMKGNATTPQVADAICKIILR"
     gene            12156..13079
                     /gene="dmlR"
                     /locus_tag="RN951_003145"
     CDS             12156..13079
                     /gene="dmlR"
                     /locus_tag="RN951_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310535.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DmlR"
                     /protein_id="HDX2528110.1"
                     /translation="MNNLPLLNDLRVFMLVARRAGFAAVAEELGVSPAFVSKRIALLE
                     QTLNVVLLHRTTRRVTITEEGERIYEWAQRILQDVGQMMDELSDVRQVPQGMLRIISS
                     FGFGRQVVAPALSALAKAYPQLELRFDVEDRLVDLVNEGVDLDIRIGDDIAPNLIARK
                     LATNYRILCASPEFIAQHGAPKHLTDLSALPCLVIKERDHPFGVWQLRNKEGPHAIKV
                     TGPLSSNHGEIVHQWCLDGQGIALRSWWDVSENIASGHLVQVLPEYYQPANVWAVYVS
                     RLATSAKVRITVEFLRQYFAEHYPNFSLEHA"
     gene            13206..13844
                     /gene="leuE"
                     /locus_tag="RN951_003146"
     CDS             13206..13844
                     /gene="leuE"
                     /locus_tag="RN951_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine efflux protein LeuE"
                     /protein_id="HDX2528111.1"
                     /translation="MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVSSGMKGGY
                     LAACGVFIGDAVLMFLAWAGVATLIKTTPILFNIVRYLGAFYLLYLGSKILYATLKGK
                     NSEAKSDEPQYGAIFKRALILSLTNPKAIVFYVSFFVQFIDVNAPHTGISFFILAATL
                     ELVSFCYLSFLIISGAFVTQYIRTKKKLAKVGNSLIGLMFVGFAARLATLQS"
     gene            14017..14376
                     /gene="yeaR"
                     /locus_tag="RN951_003147"
     CDS             14017..14376
                     /gene="yeaR"
                     /locus_tag="RN951_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1971 domain-containing protein"
                     /protein_id="HDX2528112.1"
                     /translation="MLQIPQNYIHTRSTPFWNKQTAPAGIFERHLDKGTRPGVYPRLS
                     VMHGAVKYLGYADEHSAEPDQVILIEAGQFAVFPPEKWHNIEAMTDDTYFNIDFFVAP
                     EVLMEGAQQRKVIHNGK"
     gene            14380..14562
                     /locus_tag="RN951_003148"
     CDS             14380..14562
                     /locus_tag="RN951_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1869 domain-containing protein"
                     /protein_id="HDX2528113.1"
                     /translation="MGKATYTVTVTNNSNGVSVDYETETPMTLLVPEVAAEVIKDLVN
                     TVRSYDTENEHDVCGW"
     gene            14710..14958
                     /locus_tag="RN951_003149"
     CDS             14710..14958
                     /locus_tag="RN951_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDX2528114.1"
                     /translation="MGILSWIIFGLIAGILAKWIMPGKDGGGFFMTILLGIVGAVVGG
                     WISTLFGFGKVDGFNFGSFVVAVIGAIVVLFIYRKIKS"
     gene            complement(15017..15091)
                     /gene="yoaJ"
                     /locus_tag="RN951_003150"
     CDS             complement(15017..15091)
                     /gene="yoaJ"
                     /locus_tag="RN951_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YoaJ"
                     /protein_id="HDX2528115.1"
                     /translation="MKKTTIIMMGVAIIVVLGTELGWW"
     gene            complement(15094..15192)
                     /locus_tag="RN951_003151"
     CDS             complement(15094..15192)
                     /locus_tag="RN951_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family small membrane protein"
                     /protein_id="HDX2528116.1"
                     /translation="MRIGIIFPVVIFITAVVFLAWFFIGGYAAPGA"
     gene            complement(15225..16250)
                     /gene="dgcP"
                     /locus_tag="RN951_003152"
     CDS             complement(15225..16250)
                     /gene="dgcP"
                     /locus_tag="RN951_003152"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416308.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcP"
                     /protein_id="HDX2528117.1"
                     /translation="MSDQIIARVSQSLAKEQSLESLVRQLLEMLEMVTDMESTYLTKV
                     DVEARLQHIMFARNSQKMYIPENFTVSWDYSLCKRAIDENCFFSDEVPDRWGDCIAAR
                     NLGITTFLSTPIHLPDGSFYGTLCAASSEKRQWSERAEQVLQLFAGLIAQYIQKEALV
                     EQLREANAALIAQSYTDSLTGLPNRRAIFENLTTLFSLARHLNHKIMIAFIDLDNFKL
                     INDRFGHNSGDLFLIQVGERLNTLQQNGEVIGRLGGDEFLVVSLNNENADISSLRERI
                     QQQIRGEYHLGDVDLYYPGASLGIVEVDPETTDADSALHAADIAMYQEKKHKQKTPFV
                     AHPALHS"
     gene            16433..16687
                     /gene="yoaF"
                     /locus_tag="RN951_003153"
     CDS             16433..16687
                     /gene="yoaF"
                     /locus_tag="RN951_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing lipoprotein YoaF"
                     /protein_id="HDX2528118.1"
                     /translation="MKIISFVLPCLLVLAGCSTPSQPEAPKPPQIGMANPASVYCQQK
                     GGTLIPVQTAQGVSNNCKLPGGETIDEWALWRRDHPAGEK"
     gene            complement(16709..17056)
                     /locus_tag="RN951_003154"
     CDS             complement(16709..17056)
                     /locus_tag="RN951_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416306.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HDX2528119.1"
                     /translation="MNIQCKRVYDPAEQSDGYRILVDRLWPRGIKKTDLALDEWDKEI
                     TPSTELRKAFHGEVVDYATFREQYLAELAQHEQEGKRLADIAKKQPLTLLYSAKNTTQ
                     NHALVLADWLRSL"
     gene            complement(17111..18292)
                     /gene="nimT"
                     /locus_tag="RN951_003155"
     CDS             complement(17111..18292)
                     /gene="nimT"
                     /locus_tag="RN951_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-nitroimidazole transporter"
                     /protein_id="HDX2528120.1"
                     /translation="MTCSTSLSGKNRIVLIAGILMIATTLRVTFTGAAPLLDTIRSAY
                     SLTTAQTGLLTTLPLLAFALISPLAAPVARRFGMERSLFAALLLICAGIAIRSLPSPY
                     LLFGGTAVIGGGIALGNVLLPGLIKRDFPHSVARLTGAYSLTMGAAAALGSAMVVPLA
                     LNGFGWQGALLMLMCFPLLALFLWLPQWRSQQHANLSTSRALHTRGIWRSPLAWQVTL
                     FLGINSLVYYVIIGWLPAILISHGYSEAQAGSLHGLLQLATAAPGLLIPLFLHHVKDQ
                     RGIAAFVALMCAVGAVGLCFMPAHAITWTLLFGFGSGATMILGLTFIGLRASSAHQAA
                     ALSGMAQSVGYLLAACGPPLMGKIHDANGNWSVPLMGVAILSLLMAIFGLCAGRDKEI
                     R"
     gene            18389..19210
                     /gene="nimR"
                     /locus_tag="RN951_003156"
     CDS             18389..19210
                     /gene="nimR"
                     /locus_tag="RN951_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NimR"
                     /protein_id="HDX2528121.1"
                     /translation="MMHRLNLNGYEPDRHHEAAVAFCIHAGTDELTSPVHQHRKGQLI
                     LALHGAITCTVENALWMVPPQYAVWIPGGVEHSNQVTANAELCFLFIEPSAVTMPTTC
                     CTLKISPLCRELILTLANRTTTQRAEPMTRRLIQVLFDELPQQPQQQLHLPVSSHPKI
                     RTMVEMMAKGPVEWGALGQWAGFFAMSERNLARLIVKETGLSFRQWRQQLQLIMALQG
                     LVKGDTVQKVAHTLGYDSTTAFITMFKKGLGQTPGRYIARLTTVSPQSAKPDPRQ"
     gene            complement(19167..19613)
                     /locus_tag="RN951_003157"
     CDS             complement(19167..19613)
                     /locus_tag="RN951_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HDX2528122.1"
                     /translation="MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLSTFFP
                     WIEKQGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRG
                     VTLMGSQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ"
     gene            19783..19887
                     /locus_tag="RN951_003158"
     CDS             19783..19887
                     /locus_tag="RN951_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416302.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528123.1"
                     /translation="MNDQMFVETLIITSSFFAIAVVLVLSVLLIERTG"
     gene            complement(19888..20391)
                     /gene="yeaK"
                     /locus_tag="RN951_003159"
     CDS             complement(19888..20391)
                     /gene="yeaK"
                     /locus_tag="RN951_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mischarged aminoacyl-tRNA deacylase"
                     /protein_id="HDX2528124.1"
                     /translation="MTEMAKGSVTHQRLIALLSQEGADFRVVTHEAVGKCEAVSEIRG
                     TALGQGAKALVCKVKGNGVNQHVLAILAADQQADLSQLASHIGGLRASLASPAEVDEL
                     TGCVFGAIPPFSFHPKLKLVADPLLFERFDEIAFNAGMLDKSVILKTADYLRIAQPEL
                     VNFRRTA"
     gene            complement(20434..21924)
                     /locus_tag="RN951_003160"
     CDS             complement(20434..21924)
                     /locus_tag="RN951_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416300.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDX2528125.1"
                     /translation="MKLHHRMLRHFIAASVIVLTSSFLIFELVASDRAMSAYLRYIVQ
                     KADSSFLYDKYQNQSIAAHVMRALAAEQSEVSPEQRRAICEAFESANNTHGLNLTAHK
                     YPGLRGTLQTASTDCDTIVEAAALLPAFDQAVEGNRHQDDYGSGLGMAEEKFHYYLDL
                     NDRYVYFYEPVNVEYFAMNNWSFLQSGSIGIDRKDIEKVFTGRTVLSSIYQDQRTKQN
                     VMSLLTPVYVAGQLKGIVLLDINKNNLRNIFYTHDRPLLWRFLNVTLTDTDSGRDIII
                     NQSEDNLFQYVSYVHDLPGGIRVSLSIDILYFITSSWKSVLFWILTALILLNMVRMHF
                     RLYQNVSRENISDAMTGLYNRKILTPELEQRLQKLVQSGSSVMFIAIDMDKLKQINDT
                     LGHQEGDLAITLLAQAIKQSIRKSDYAIRLGGDEFCIILVDSTPQIAAQLPERIEKRL
                     QHIAPQKEIGFSSGIYAMKENDTLHDAYKASDERLYVNKQNKNSRS"
     gene            complement(22105..>23340)
                     /locus_tag="RN951_003161"
     CDS             complement(22105..>23340)
                     /locus_tag="RN951_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDX2528126.1"
                     /translation="NVKLIPQMNYLMVVVALFFLNAVIFLFMLMKYFTNKQILPTLIL
                     SLAFLSGLIYLVETIVIIHKPINGSTLIQTKSNDVSIFYIFRQLSFICLTSLALFCYG
                     KDNILDNNKKKTGILLLALIPFLVFPLLAHNLSSYNADYSLYVVDYCPDNHTATWGIN
                     YTKILVCLWAFLLFFIIMRTRLASELWPLIALLCLASLCCNLLLLTLDEYNYTIWYIS
                     RGIEVSSKLFVVSFLIYNIFQELQLSSKLAVHDVLTNIYNRRYFFNSVESLLSRPVVK
                     DFCVMLVDINQFKRINAQWGHRVGDKVLVSIVDIIQQSIRPDDILARLEGEVFGLLFT
                     ELNSAQAKIIAERMRKNVELLTGFSNRYDVPEQMTISIGTVFSTGDTRNISLVMTEAD
                     KALREAKSEGGNKVIIHHI"
BASE COUNT         6039 a         5658 c         5929 g         5714 t
ORIGIN      
        1 cggtcagtcc gcacgctata accagattgt tcagctaaga aagaaaacca gagttgctaa
       61 tcaaagggcg aacacaacgg catgtttatg tttatttata tagttagttt tatagataaa
      121 attgaaatta taaatataaa taatgaatta gcagaagcat caacagtaat atcttattct
      181 ctggtcgatt tatgtaaaac cgaccagtat tatcgataaa ttatcgtctg acttattttg
      241 cttcgataaa gcttacaccg cagccacaat cttaatttca actttatact tcgggttcat
      301 caaacccgct tgtaccgtgc agcgcaccgg cgcatgaccc gcgacaaccc aggcatccca
      361 cgctttattc atcgccgcga agtcgttttt atcggccagg aaaatggtgg catccagaat
      421 gctcgattta ttgctgccct gtttttccag cacggcgtca atctgtgcca gcgtgttggc
      481 ggtttgctca aaggcatcgg cgtcgaggtt ttccggtaca ccagtgtagt agagcgtgtt
      541 gttgtggatt actacatcag accagcgggc ttcagcatcg atacgaacga tagtcatcat
      601 tttgtcctca ttatacttcc attttcgtgc tgcaaagact gccacaatgt gaggtcgccg
      661 tcaccacttc aactggcgaa agcgccctca tcctgacata atccctgttc aaatcaacag
      721 ggggtagtgt gacggacgat tttgcaccag acggtcagct ggcgaaagcg ataccaggct
      781 ttaagccgcg agaaccacag cgacagatgg cggtagccgt cacccaggcg atagaaaaag
      841 gccagccgct ggtggtggaa gcaggaaccg gtacgggcaa aacctacgct tacctggctc
      901 ctgcgctgcg ggcgaaaaag aaagtcatta tctcgaccgg ctcaaaagcg ttgcaggatc
      961 agctctacag ccgcgatttg ccaacagtct caaaggcatt gaaatatacg ggcaacgtgg
     1021 cgctgctgaa aggacgctca aactacctct gcctcgaacg tctcgaacag caggcgctgg
     1081 cggggggcga tctgccggta caaatcttaa gcgatgtgat cctgctgcgc tcctggtcta
     1141 atcaaacagt cgatggtgat atcagcacct gcgtcagcgt ggcggaagat tcacaggcgt
     1201 ggccgctggt caccagcacc aacgacaact gtcttggcag cgactgcccg atgtataaag
     1261 attgctttgt ggtcaaagca cgtaaaaaag cgatggacgc cgatgtggtg gtggtaaacc
     1321 atcatctctt tctggcggat atggtggtta aagagagtgg atttggcgaa ctgatcccgg
     1381 aagcggacgt catgatcttc gacgaagccc accagctacc ggacattgcc agccagtatt
     1441 ttggtcagtc actctccagt cgacaactgc tcgacctggc aaaagacatc accatcgcct
     1501 accgcaccga attaaaagac acccagcagt tacaaaagtg cgctgatcgt cttgcccaga
     1561 gtgcgcagga ttttcgtctg caactcggtg agccaggtta tcgcggtaac ctgcgtgagc
     1621 tgttagctaa tccgcaaatt cagcgggcat ttttactgct cgatgacacc ctggaacttt
     1681 gttatgacgt ggcgaaactg tcactggggc gttccgcctt gctggatgcg gcatttgagc
     1741 gcgccacgtt gtatcgcaca cggctgaagc ggctaaaaga gatcaatcag ccgggctaca
     1801 gctactggta cgaatgcact tcgcgccatt ttactctggc tctcacgccg ctcagcgtgg
     1861 cggataaatt caaagagtta atggcgcaaa aacccggtag ctggatcttc acctcagcaa
     1921 cgctgtcggt gaacgacgat ctgcatcatt tcacctcgcg gcttggcatc gaacaggccg
     1981 agtcgttgct gttgcccagc ccatttgatt acagccgcca ggcgttactc tgtgtgccgc
     2041 gcaatctgcc gcaaaccaac cagccaggtt ctgctcgcca gttagcggca atgctgcgac
     2101 cgatcatcga agctaacaac ggtcgttgtt ttatgctttg tacctcgcac gccatgatgc
     2161 gcgatctggc cgagcagttc cgcgctacca tgacgcttcc tgtattgttg cagggggaaa
     2221 ccagcaaagg gcaactgttg cagcaatttg tcagcgccgg taatgcgctt cttgtggcaa
     2281 ccagcagttt ctgggaaggg gtggacgtgc gtggcgatac attgtcattg gtaattatcg
     2341 acaaattgcc gtttacctcg ccggatgatc cactgttaaa agcgcgcatg gaagattgtc
     2401 gtttgcgcgg tggcgacccg ttcgatgaag tgcaactacc agatgccgtc attactctca
     2461 aacagggggt agggcgactg attcgcgacg ccgacgatcg tggcgtgctg gtgatttgtg
     2521 acaatcggct ggtgatgcgt ccttacggcg cgacgtttct cgccagtctg ccgcccgcgc
     2581 cacgcacccg tgacattgcc cgtgcggttc gtttccttgc gataccatcc tccaggtaat
     2641 ttgttacgga gtatggtatg atgcgcgcct ttttattgat ctaagcacga agacccatgc
     2701 gaattctggc tatcgatacc gcgacagagg cctgctctgt cgccctgtgg aacgacggta
     2761 ctgtcaacgc tcattttgag ctttgccctc gtgaacatac tcaacgaatc ttaccgatgg
     2821 tgcaggatat cctgaccacc agcggaactt ccctgactga tattaacgct ctggcttacg
     2881 ggcgcggccc cggtagcttt actggcgtgc gcattggtat tggcatcgcg caagggctgg
     2941 cgcttggcgc ggaattaccg atgattggcg tctccacgct aatgacgatg gcgcaagggg
     3001 cgtggcgcaa aaacggcgca acccgcgtgc tggcagccat tgacgcgcga atgggcgaag
     3061 tttactgggc cgaatatcag cgtgatgaaa acggtatctg gcacggtgaa gaaaccgaag
     3121 ccgtactcaa acccgaaatc gtccatgaac gaatgcaaca gctttccggc gaatgggtga
     3181 cggtagggac gggctggcaa gcttggccgg atctcggtaa agagagcggg ctggttttgc
     3241 gcgatggcga agtgttactg cctgctgctg aagatatgct gccgattgcg tgtcagatgt
     3301 ttgctgaggg taaaacggtg gcggtggaac atgccgaacc ggtttattta cgtaacaacg
     3361 tcgcatggaa gaaacttccg ggcaaagaat gaatcttaag agtatgccct gagaaaaaaa
     3421 ggagtcgcac catggcggtt caaaagaatg ttatcaaagg catactggca ggtacgtttg
     3481 cgctaatgct gagcggttgt gtcactgtgc cggacgccat taaaggcagc agtcccacgc
     3541 cgcaacaaga tttagttcgg gtgatgagtg cgccgcagct gtacgttggt caggaggcac
     3601 gctttggtgg caaagtggtt gcggtacaaa accagcaagg gaaaactcgc ctggaaattg
     3661 ctaccgtacc gctggacagc ggagccagac cgacgctggg agaaccttct cgcggtcgca
     3721 tttatgccga tgtgaacggt tttctggacc cggtggattt ccgtggacaa ctggttacgg
     3781 tagtcgggcc aatcactggt gcggttgacg gcaaaatcgg caatacgccc tataaattta
     3841 tggtgatgca agtaacgggt tacaaacgtt ggcatttaac ccagcaggtg attatgccgc
     3901 ctcagccgat tgatccatgg ttttatggcg gtcgtggctg gccctatggc tacggcggat
     3961 ggggctggta taatcccggc cccgcgagag tacaaacagt tgtaactgaa taattgcttg
     4021 tttttaaaga atgcagaaac agcggctggt ccgctgtttc tgcattctta cggtaaagat
     4081 aaaaataaat agtgacgcgc ttcgcaacct tttcgttggg taattatcaa gctggtatga
     4141 tgagttaata ttatgttaac ggcatgtata tcatttgggg ttgcgatgac gacgaacacg
     4201 cattttagag gtgaagaatt gaagaaggtt tggcttaacc gttatcccgc ggacgttccg
     4261 acggagatca accctgaccg ttatcaatct ctggtagata tgtttgagca gtcggtcgcg
     4321 cgctacgccg atcaacctgc gtttgtgaat atgggggagg taatgacctt ccgcaagctg
     4381 gaagaacgca gtcgcgcgtt tgccgcttat ttgcaacaag ggttggggct gaagaaaggc
     4441 gatcgcgttg cgttgatgat gcctaattta ttgcaatatc cggtggcgct gtttggcatt
     4501 ttgcgtgccg ggatgatcgt cgtaaacgtt aacccgttgt ataccccgcg tgagcttgag
     4561 catcagctta acgatagcgg cgcatcggcg attgttatcg tgtctaactt tgctcacaca
     4621 ctggaaaaag tggttgataa aaccgccgtt cagcacgtaa ttctgacccg tatgggcgat
     4681 cagctatcta cggcaaaagg cacggtagtc aatttcgttg ttaaatacat caagcgtttg
     4741 gtgccgaaat accatctgcc agatgccatt tcatttcgta gcgcactgca taacggctac
     4801 cggatgcagt acgtcaaacc cgaactggtg ccggaagatt tagcttttct gcaatacacc
     4861 ggcggcacca ctggtgtggc gaaaggcgcg atgctgactc accgcaatat gctggcgaac
     4921 ctggaacagg ttaacgcgac ctatggtccg ctgttgcatc cgggcaaaga gctggtggtg
     4981 acggcgctgc cgctgtatca catttttgcc ctgaccatta actgcctgct gtttatcgaa
     5041 ctgggtgggc agaacctgct tatcactaac ccgcgcgata ttccagggtt ggtaaaagag
     5101 ttagcgaaat atccgtttac cgctatcacg ggcgttaaca ccttgttcaa tgcgttgctg
     5161 aacaataaag agttccagca gctggatttc tccagtctgc atctttccgc aggcggtggg
     5221 atgccagtgc agcaagtggt ggcagagcgt tgggtgaaac tgaccggaca gtatctgctg
     5281 gaaggctatg gccttaccga gtgtgcgccg ctggtcagcg ttaacccata tgatattgat
     5341 tatcatagtg gtagcatcgg tttgccggtg ccgtcgacgg aagccaaact ggtggatgat
     5401 gatgataatg aagtaccacc aggtcaaccg ggtgagcttt gtgtcaaagg accgcaggtg
     5461 atgctgggtt actggcagcg tcccgatgct accgatgaaa tcatcaaaaa tggctggtta
     5521 cacaccggcg acatcgcggt aatggatgaa gaaggattcc tgcgcattgt cgatcgtaaa
     5581 aaagacatga ttctggtttc cggttttaac gtctatccca acgagattga agatgtcgtc
     5641 atgcagcatc ctggcgtaca ggaagtcgcg gctgttggcg taccttccgg ctccagtggt
     5701 gaagcggtga aaatcttcgt agtgaaaaaa gatccatcgc ttaccgaaga gtcactggtg
     5761 actttttgcc gccgtcagct cacgggatac aaagtaccga agctggtgga gtttcgtgat
     5821 gagttaccga aatctaacgt cggaaaaatt ttgcgacgag aattacgtga cgaagcgcgc
     5881 ggcaaagtgg acaataaagc ctgagcgtta agtcagtcgt cagacgccgg ttaatccggc
     5941 gttttttttg acgcccacta aagagaaaac aatttgaatt accaaatgat taccacggac
     6001 gatgcgctgg cttctttgtg tgaagccgtc cgtgcctttc cggcgatagc cctggatact
     6061 gaatttgttc gtacgcgcac ttattacccg cagctggggt tgattcaact tttcgatggc
     6121 gagcatctgg cgctaatcga tccactcggg atcaccgact ggtcaccgct gaaagcgatc
     6181 ctgcgcgatc cgtccatcac aaaatttctc catgcaggca gtgaagatct ggaagtgttc
     6241 ctcaatgtct ttggcgaatt accacaaccc ttgattgaca cgcaaatcct tgctgccttc
     6301 tgcggacgcc cgatgtcatg gggtttcgct tccatggtgg aagagtattc cggcgttacg
     6361 ctggacaaga gtgaatcgcg caccgactgg ctggccagac cgctgaccga acgtcagtgt
     6421 gaatacgcag cggcggatgt ctggtatctg ttaccgatca ccgccaagct tatggtagaa
     6481 acggaggcct ccggctggct acctgcggcg ctggatgaat gccgcctgat gcaaatgcgt
     6541 cgtcaggaag tcgttgcgcc ggaagatgcc tggcgtgata tcaccaatgc ctggcaatta
     6601 cgcacacgcc aactggcctg tctgcaactg ttagccgact ggcgactgcg caaggcgcga
     6661 gagcgcgatc tggcggtgaa ctttgtcgtg cgtgaagagc atttgtggtc ggtagcgcgt
     6721 tatatgccgg gaagtttagg cgaactggac agcctgggtt tatccggtag cgaaatccgc
     6781 tttcacggta aaacgctgct agcgctggtg gaaaaagcgc agacattgcc ggaagatgcc
     6841 ttaccgcagc cgatgcttaa cctgatggac atgccgggtt atcgtaaagc gtttaaagcg
     6901 attaagtcgc tgattactga cgtgagcgaa acgcataaga tcagcgccga attgctggca
     6961 tcgcgtcggc aaatcaacca actgctgaac tggcactgga aactgaaacc gcagaacaat
     7021 ttgccggagc tgatttccgg ctggcgtggt gagctgatgg cggaagcatt acacaattta
     7081 ttgcaggaat atccgcagta aaatcttccg aagccggact gggcgcgctc agcgccacat
     7141 ccggcttcgg caaactacaa atccaacacc aggcgtttac ccttcgcacg cgaacaacag
     7201 atcaacatac tttgctggct ggcacgctct tcatcgctaa aatattgatc ccgatggtca
     7261 gcttcacctt ccagtattgc tgtttcgcag gttccgcata ccccttcacg acataaacat
     7321 tccactttcg cggctttatt attttcaata acctgcaaaa tagtcatctc ttccggcacc
     7381 acaaactctt ttccggaacg ggcaagcacc agggtaaatg catcgccggt tttgtcttcg
     7441 atagcaaatt gctcaaagtg cagcgtatcg gcggcgatgt ccagacgcgc agcttcactt
     7501 cttaccgctt caattagcgc ctcggggcca caggtataaa cgtgtgtgcc aggttcgata
     7561 tccgccaata atcgcgctaa ttccagtcgt gttccggttg atgaatgatg caaatggact
     7621 ttctcagcct gcggatgctg gactagctca tcacgaaatg cgcaactttc tggatttcgc
     7681 gagcagtaat gtagctgcca gtcgacgtcg ctgtgttgca gctctgccat gtgcgacagg
     7741 aaaggggtga taccaatacc gcccgcgata aacagatgct ttctggctga gggaattagc
     7801 gcaaacaggt tattaggcgt tgaaatcgtt aaccgatcgc ccacttttac ctgctgatgc
     7861 aaaaagcggg aaccgccgcg cgagttttcc tccagccgaa cggcaatctg ataacaagag
     7921 gtgtcatgcg gcgaactcag tagtgaatac gcattgctgt actggttatc accatcgctc
     7981 atctgcacaa tgacgtgact tcctccggta aacgcaggta atggtttgcc atcggttgcc
     8041 accagcgtga agcgtttcac ctgttcggta aggggttcaa cctggctcac ctgtacttca
     8101 aacatttgat agtctgacat tgctgtactc catcaaaaat cagcccagcg gcggaaaata
     8161 ccgccgccga tgtcattagt ccttaaacac ctgcgccagc agattatgga aatgggcgat
     8221 accatgttcg gaaatgccac taccgctact gtcggccatg atgcgcccct gaccacgata
     8281 gccacgcgat ttcagccctt tctgtacgct ttcaaccaga cgtaaatctt ccggacggaa
     8341 cacatcgcga taccactcaa tcagcgattt ttgctcgtcg gttaactctt cattggtgaa
     8401 gtaaatatcg tagttttgca gggtagtttc agaatccacc gggaattcat aaatgaccgt
     8461 catcatccct ttgatcgggg tgacgttcag catcgtgcac ggccacagcc agaaaccgtg
     8521 gaatgccgca tccgtaccct cttcaaattt aaacgactgt tcggacggtt tggcgaaacc
     8581 gtattgcagc gtccagttac cgtgcatggt gtgccagtaa cgatcaacct gtacggagtc
     8641 ggagaaacct ggatgcgccg gaccacagtg atagcactcg agatagttat cgacaatgtt
     8701 cttccagttg gcaggcgtgc gggtggtaaa gcgggccgcc agtttcagat cgtggacttc
     8761 cgggcaggct tccagcactt tcgcgcccag gccgggtaat tgatcttcta cgctggtggc
     8821 gttggggtcc atgttgatga agacgaatcc ggcatattct tccagacgca ccggaaccag
     8881 ttgcgctttg tcgctatcga aattggcgac gttttcgcag ttacgtgcat gggccaggtt
     8941 gccatcgagt ttgaatgccc atgcgtgata cgggcaggta atcacatttt ttgcttttcc
     9001 ttcaccgctc aacaactgat gaccacggtg cggacacacg ttatagaacg cgcgcaaaac
     9061 cttatcacga ccgcgtacca gcacgatgct ttcgccaatg atctcacgcg tcacataatc
     9121 attggcattc gccagttcgc tgctgtgagc gacgcaaatc cagcttttgg cgaagacgtt
     9181 ctctttttcg tgttcaaacg cgttctgatc ggtataaaaa cgggcaggaa tggtccacgc
     9241 ctcttgcggg ttagcgcaaa aattttcggg tagtacaaag tcagggctca gattgctcat
     9301 agggatacct ttatcgttag gatgatggcg ctcagttgtc gcctttgaat acggttcccg
     9361 cagggagcac tggcgttttt tccagggctt caaccggtgt ctgcgggaga taatgttcaa
     9421 cttgatgagc cggaatgtcg gcgtaatcct gtttcagcca gcgaataaac ccgccgactt
     9481 tcaccagtaa aatgacgagg aagggaaggg ctgtgagcac gacggtggtt ttcatcgttt
     9541 ccagcgaagc accggtaaac aagatggaaa gcgggatcag agtgatcacc acgcaccaga
     9601 aaagacgcag cccacggtca ggatcgtcac cttcctggag attacgcgta ctggtcgccg
     9661 ccatggtgta ggccactgca tccatatgcg aggcaaggaa aataatcatc acgcccaggt
     9721 atgcggcgag gaacaattta ccggctggca acgacatcag aacttgctgt acagctgttt
     9781 cgccgcccag tgtttccagc acctgtggga cgttgattac gccattgata aactgatgaa
     9841 tggcatagct ttccattacg ccaaagaaga accagcaacc gacggtgctg ccgaggatca
     9901 gtccccagat aacttcttta atcttacgac cgcgggaaac gcgggtgaca aacattgcta
     9961 cgccaggggt gtatgagatc caccacagcc agtagaaaac ggtccagttg cgggtaaatg
    10021 aaccatcgcc aagcggatcg gtgaataagc tcatttgcag gaagttttgc gtggtcaggc
    10081 cgatggcatt gatgatgctg ttggtaataa attcggttgg gccgacaatc agcaccagta
    10141 atggcagcag gaacgcgccc cagccaacca ttttgctcag acgttgcaaa ccgttgttga
    10201 taccaatcca cgagcttagg caaaaaatgc cgccggaaag caggatcaca aatgcctgca
    10261 cggtgaagtt atcgggtaaa ccggtcagcg cggaaagccc acgggtaaag gttgctgcgg
    10321 taacaacaag ggaaatggtc agtgcgccga cagtggcgat caggaacatc aaatcgacca
    10381 gttttcccca tgggccttgc gggcgaacgc cggtaatagc agcaataatg ccggaaaggc
    10441 tcagaccttt gtttttccgc acatgaaagt gataagccat gattaatgag gccagcgtat
    10501 aagttgccca ggcgctgatg ccccagtgga agaaagagta gggaacgcta aattcgagtg
    10561 cctgttgtga acgcggtgcg atatttaatc caggtgtttg ataataatag gcccattcag
    10621 caacccccca ataaagcgta gaagaaccta aaccggcaca aataaacata aacagccagg
    10681 agagcgtgct gtattccggt tttccttcgc caagacgaat attgccgtat ttactggtgg
    10741 ctaaataaat caccagtccc attgccagca aaaccaatac ctgtacggcg gaacctaacg
    10801 tacgcgtaac aaaatttgca tgttacataa attaaacaat taagaatacg gaaagccata
    10861 aaacacgaaa cggaaacaat aaaaggtgaa atgacgcagg ttatttactg caaagaacga
    10921 ataaaaaaac cgcgtcagtg acgcggttca aataaactgg tttgacctta acgcaaaata
    10981 attttgcaaa tcgcgtcggc aacctgtggc gtggtggcat tgcctttcat atcaggtgtt
    11041 ttcggcccgt gagcaatcac ttcttcaatt gctgccagaa taccgttatg cgcttgctgg
    11101 aaacgctcat cgccattgcc gagaaaatcg agcatcattg ccccggccca aatcgtggcg
    11161 atagggttag caatattttt cccgtagata tccggcgcgg aaccgtggac aggctcgaag
    11221 agcgacggga aagtgcgttc cggattcagg ttggcggatg gggcaatgcc aatggtgccg
    11281 gtgcaggccg ggccaagatc ggaaaggata tcgccaaaca aattggacgc caccaccaca
    11341 tcgaatcgtt ccggctgcat cacaaaacgc gcgcagagaa tatcaatatg ctgcttgtcc
    11401 cagcggatct ccgggtaatt ctcggccatt gcttccactc gctcatccca gtacggcatg
    11461 ctgatggcta aaccgttcga tttagtggca gaagttagtg tcttacgtgg acggctttgc
    11521 gcaagttcga aggcataacg caaaatgcga tcgacaccac ggcgggtaaa taccgattcc
    11581 tgaatgacga cttcatgctc tgtaccttca ttcactctac cgccgagcga ggaatattcg
    11641 ccttcggtgt tttccctgac cacgtaaaaa tcgatgtcgc caggctgttt tcccgccagc
    11701 gggcagggaa cgccaggaaa gagacgaacc gggcgcaggt tgacgtactg gtcgaattca
    11761 cgacgaaatt tcagcagcga accccacaac gaaatatggt ccggaacggt atccggccag
    11821 ccgacggcac caaaatagat ggcgtcgaaa cggctaagtt gctcatgcca gtcgtccggc
    11881 atcattttac cgtgatggct gtaatactcg cagctcgccc actccatttg ctcaaaactc
    11941 aaggcgaagc cccagcgctc agcggcagcc tgtaacacgc gaatcccttc aggaaggact
    12001 tctttgccaa tcccgtctcc cgggatcgca gcaatacgca tcgttttcat cattgggttc
    12061 tcacttcctg accatcaaaa ttgacaacat caccatccta taattgactg aaaaggaatt
    12121 aatccccgta actggtgaaa cataaaacac gaatcatgaa taatttaccg ctgctgaatg
    12181 atttgcgcgt ctttatgctg gtggctcgcc gggctggttt tgccgccgtg gcggaagaac
    12241 tgggcgtttc accggcgttc gtcagcaagc gcatcgcctt gctggagcaa acgctaaacg
    12301 tggtgttgtt acaccgcacc acccgccgcg tcaccattac cgaagaagga gagcggattt
    12361 atgaatgggc gcagcggatt ttgcaggatg tcggtcagat gatggacgaa ctttctgacg
    12421 tgcgtcaggt gccgcagggg atgctgcgta ttatcagcag ctttggtttt ggacgacagg
    12481 tggtggctcc ggcgttatca gcgctggcga aggcgtatcc gcaactggaa ttacgttttg
    12541 atgtggaaga ccgactggtc gatttggtca atgaaggtgt cgatctcgat attcgcattg
    12601 gcgatgacat cgcccctaat ttaatcgccc gcaaactggc gaccaattac cgtattctct
    12661 gcgcgtcgcc ggaatttatt gcgcaacatg gcgcgccgaa acatttaacc gatctttctg
    12721 cattgccgtg cctggtcatt aaagagcgcg atcatccttt tggtgtctgg caattacgca
    12781 ataaagaagg tccccatgcg attaaagtca ccggcccact gtcgtctaat catggagaaa
    12841 ttgtccatca gtggtgtctc gatgggcagg ggattgctct gcgttcctgg tgggatgtta
    12901 gcgaaaacat tgccagtggt catttagtgc aagtgctacc ggaatattac cagccagcga
    12961 acgtctgggc cgtttatgtt tcaaggctgg cgacgtcagc gaaagtgcgg ataacggtag
    13021 aatttttacg ccagtatttt gccgagcact acccgaattt ttcactggag catgcctgat
    13081 taatgattca attatcgggt tgatatcagg ttaaaacctg attttctcct ttctaagccg
    13141 ctacagattg gttagcatat tcacctttaa tcgcgcatga tcgaaagata attaaagagg
    13201 ttaatgtgtt cgctgaatac ggggttctga attactggac ctatctggtt ggggccattt
    13261 ttattgtgtt ggtgccaggg ccaaataccc tgtttgtact caaaaatagc gtcagtagcg
    13321 gtatgaaagg cggttatctt gcggcctgcg gtgtatttat tggcgatgcg gtattgatgt
    13381 ttctggcatg ggctggagtg gcgacattaa ttaagaccac cccgatatta ttcaacattg
    13441 tacgttatct tggtgcgttt tatttgctct atctggggag taaaattctt tacgcgaccc
    13501 tgaagggtaa aaatagcgag gccaaatccg atgagcccca atacggtgct atttttaaac
    13561 gcgcgttaat tttgagcctg actaatccga aagccattgt gttctatgtg tcgtttttcg
    13621 tacagtttat cgatgttaat gccccacata cgggaatttc attctttatt ctggcggcga
    13681 cgctggaact ggtgagtttc tgctatttga gcttcctgat tatatctggt gcttttgtca
    13741 cgcagtacat acgtaccaaa aagaaactgg ctaaagttgg caactcactg attggtttga
    13801 tgttcgtggg tttcgctgcc cgactggcga cgctgcaatc ctgatgcttt cagcccgcgt
    13861 tgtcgcgggc ttcccatcta taatcctccc tgattcttcg ctgatatggt gctaaaaagt
    13921 aaccaataaa tggtatttaa aatgcaaatt atcaggcgta ccctgaaacg gctggaataa
    13981 accgttttca gcgcattcac cgaaggaggg aaaaggatgc ttcaaatccc acagaattat
    14041 attcatacgc gctcaacgcc tttctggaat aaacaaactg cacctgccgg aatattcgaa
    14101 cgtcatcttg ataaaggaac gcgcccgggg gtttacccac gcctttccgt tatgcatggg
    14161 gcggtcaaat atctcggcta cgctgatgaa cacagtgcag agcctgatca ggtgatcctt
    14221 atcgaagcgg ggcagtttgc ggtgttccct ccagaaaagt ggcacaacat tgaagccatg
    14281 actgacgata cttatttcaa cattgacttc ttcgtggctc ctgaagtcct gatggaaggt
    14341 gcgcaacaac ggaaagtcat tcataacggg aaatgaatca tgggcaaagc aacgtatacc
    14401 gtgaccgtca ccaataacag caatggcgtt tctgtcgatt atgaaacaga gacgccgatg
    14461 actttgctgg tgccagaagt ggcggctgaa gtgataaaag atctggtgaa taccgtacgt
    14521 tcttatgaca cggaaaacga acatgatgtt tgtggttggt aattatcact gatcgttgat
    14581 ggcgcaattt ctgcgccatc gcaaaaaaaa cctccgtgat gctcgtcaca aatcttgccc
    14641 tcccgatgtt gtgctatgct ttttatcagc gactaacccg ctaatgcaaa acagataagt
    14701 gaggaaacaa tgggcattct gtcatggatt atttttgggc ttattgccgg tattctggcg
    14761 aagtggatca tgccaggtaa agatggaggt ggattcttta tgactatcct gctggggata
    14821 gtcggtgccg tagtcggcgg atggatcagc acgctgtttg gctttggtaa agtcgatggc
    14881 ttcaattttg gcagcttcgt ggttgccgtt attggtgcga ttgtcgtgct atttatctac
    14941 aggaagatta aaagttaacg cttaaattgc acaaaggctg cacacaggca gcctttgcta
    15001 ttttttagag gtgacgttac caccatccca gctcagtgcc gagtacgaca ataatcgcca
    15061 cacccatcat aataatcgtt gtttttttca tctttatgct cccggggcag catagccgcc
    15121 aataaaaaac catgctaaaa atacgaccgc tgtaatgaag attacaaccg gaaaaataat
    15181 accgattcgc atgttatcac caatcaaaag gatgtgaata cgcctcagga atgtagcgct
    15241 ggatgcgcga caaaaggtgt tttctgtttg tgttttttct cctgatacat cgcaatatcg
    15301 gcagcatgca gggcactgtc tgcatcggtt gtttcaggat cgacttctac tatgccaaga
    15361 ctggcaccgg gataatacaa atcaacatca cctaagtgat attctccacg tatttgctgc
    15421 tgaatgcgtt ctcgcagcga cgaaatatcc gcattctcgt tgtttagtga aacaactaaa
    15481 aactcatcac cgccgagacg accaataact tcgccatttt gctggagcgt attaaggcgc
    15541 tcgccaacct gaatgagaaa cagatcgcca ctattatgac caaaacgatc attgattaat
    15601 ttgaagttat ccagatcgat aaacgcgatc attatcttat ggttaagatg ccgggcgagg
    15661 gaaaacagtg tcgtcagatt ttcaaaaatc gcccgccgat tcggtagccc ggttaacgag
    15721 tcggtatacg attgcgcaat cagcgcagca ttggcttcgc gcagctgttc aaccagtgcc
    15781 tctttttgaa tatattgtgc aatcagtccg gcgaataact gtaaaacctg ttccgcgcgt
    15841 tcactccact ggcgcttctc actgctggcg gcgcaaagcg tgccatagaa tgatccatcc
    15901 ggtaagtgaa ttggcgtgct cagaaatgtg gtgatgccaa gattgcgtgc cgcaatacag
    15961 tcaccccaac ggtcggggac ttcatcgctg aaaaagcagt tttcatcaat ggcgcgtttg
    16021 cataacgagt aatcccacga gacggtaaaa ttctccggga tgtacatttt ctggctgtta
    16081 cgggcaaaca taatatgctg caggcgcgct tcgacatcca ctttggtcag gtaggttgat
    16141 tccatatcag tgaccatttc cagcatctcc agaagctgtc ggaccagact ttccagtgac
    16201 tgttctttgg caagggattg cgagacgcgg gcgataatct gatctgacac ggaacaactc
    16261 caggatacgg cgggtaaatg ctgattattt aatctttgca ggcatgataa aacatcatca
    16321 acaaagatga aacaagacgt aatatgtttt gagtgaatgt aataaaaata gtgctgcaaa
    16381 acaaaacgat accgcgatac tctaatcttg gataaatatg tgagatcaat aaatgaaaat
    16441 tatcagtttt gttctgcctt gcttgctggt cctggctggt tgttcaaccc cttctcagcc
    16501 agaagcacct aaaccgccgc agattggtat ggcaaatccg gcgtcggtct attgccagca
    16561 gaagggcggg acgctcattc cagtgcagac agcgcaaggg gtcagcaaca attgcaaatt
    16621 accgggcggt gaaacgattg atgaatgggc attgtggcgg cgtgaccatc cggctggtga
    16681 aaaataaccg ccggatgctg tactaaaatc acaagctacg tagccagtcg gccagcacca
    16741 gcgcatggtt ctgcgtggtg ttttttgctg agtagagcag ggtcagcggc tgttttttgg
    16801 cgatgtccgc cagccgcttt ccttcttgct cgtgttgcgc cagttctgca agatattgct
    16861 cgcgaaaggt tgcataatcg acgacttcgc cgtgaaaggc tttgcgcagt tccgttgacg
    16921 gcgtgatttc tttatcccac tcatcaaggg ctaaatcggt ttttttgata ccgcgcggcc
    16981 agaggcggtc gaccagtatg cgataaccat cgctctgttc agccggatca taaacgcgtt
    17041 tgcactgaat attcatcgtg tttgttctcc ctttcacgca tgatttgtta cgtcactata
    17101 gcaccggata ttagcgaatt tctttgtctc tcccggcgca aagtccgaaa atcgccatca
    17161 gtagtgaaag tatggcaaca cccataagtg gtacagacca gttaccgtta gcatcgtgta
    17221 ttttacccat cagcggcggc ccacaggctg ccaacaaata cccgacggat tgtgccatcc
    17281 ccgagagtgc cgccgcctga tgcgcagaac tagcccgcag accaatgaac gtcaacccca
    17341 gtatcattgt tgcgccggaa ccaaaaccga aaagcagagt ccaggtgatc gcgtgcgctg
    17401 gcataaagca gagcccaacc gcgcccactg cgcacatcaa ggcaacgaac gctgcaatac
    17461 cacgctgatc tttcacatga tgtaagaaaa gtgggatcag caaaccgggt gctgctgtgg
    17521 ctagttgcag caaaccatgc agtgaacccg cctgtgcttc gctatagccg tgactgatga
    17581 ggatcgccgg aagccagcca ataatcacgt aatagaccag tgagttgatc ccaagaaaca
    17641 atgtgacctg ccaggcaagc ggcgaacgcc agataccccg agtatgtaag gcgcgcgagg
    17701 tactcaaatt tgcatgttgt tgacttcgcc actgtggcag ccataaaaaa agagccagca
    17761 gaggaaaaca catcagcatg agcaacgcgc cttgccagcc aaaaccgttc aaagccagcg
    17821 gcacgaccat agccgatccc agtgccgctg cagctcccat tgtcagggaa tatgcgccgg
    17881 taagtctggc gacggaatga gggaaatcgc gtttaattaa tcctggcagt aagacattgc
    17941 ctaatgcaat cccaccgcca atgaccgctg taccgccaaa taataagtaa ggcgaaggga
    18001 gagagcgaat tgcgatacca gcacagatca aaagtaacgc ggcaaacagg ctacgttcca
    18061 taccaaaacg tcgcgctacc ggggcagcca aaggtgagat tagcgcaaag gccaataatg
    18121 gcagggtggt caataagccg gtttgcgctg tcgtcagcga gtaagcggaa cgaatcgtat
    18181 ccagtaacgg tgctgcgccg gtaaaggtga cgcgtaatgt tgtggcaatc atcagaatgc
    18241 cagcgataag gacaatcctg tttttgccgc ttaatgaagt tgaacaggtc atatgcttct
    18301 cattgttaca aacgaggctg taccttaccg tttttattgt tatgttgaat caagctaaaa
    18361 tgacaaatta tcgctaagtt cggacaaaat gatgcacagg ttgaatctca atggctatga
    18421 acccgaccga caccatgaag ccgcggtcgc attttgtatt cacgccggaa cggatgagtt
    18481 aaccagtcct gtacatcagc accgcaaagg acagctgata ctggcgctac atggtgcaat
    18541 tacctgtacg gtggaaaatg ctttgtggat ggtgccgcca caatatgcgg tttggatacc
    18601 gggcggggtg gaacatagca atcaagtaac agctaatgct gaactctgtt ttctgtttat
    18661 cgaacccagc gcagtgacaa tgccgacaac atgttgcaca ttgaaaatat cgcccttatg
    18721 ccgggaatta attttaaccc tggcaaacag gacgacgact cagcgtgctg agccaatgac
    18781 ccgcagatta attcaggtcc tgtttgatga actccctcag cagccacaac aacagctgca
    18841 cctgcccgtt tcttctcatc ctaaaatccg cacgatggtg gagatgatgg cgaaagggcc
    18901 tgtcgagtgg ggggcattgg ggcaatgggc tggctttttt gcgatgagtg aacgcaatct
    18961 tgcccgactg atagtaaaag agacggggtt gagttttcgc cagtggcgtc agcagttaca
    19021 gctgattatg gcgcttcagg gattagtgaa aggcgatact gtacagaaag ttgctcatac
    19081 gctggggtat gattcaacaa cggcctttat tactatgttt aagaaaggcc tggggcaaac
    19141 gccaggccga tatattgcga gattaactac tgtttcccca caatcagcga aaccagaccc
    19201 gcggcaataa gcggcccaac cggtacgccg cgaaacagcg ctacgcctaa aacagtgcct
    19261 accagcagcc cggcgaccag ttgcggctgg ctgcccatta acgtcacgcc gcgcccaccc
    19321 agccaggaga caatcacgcc tactgcaatc gccaccagtg atttccagtt cagaaacgag
    19381 tgaatcaagg ttgagggcgg tagcgtcccg ctggcgatgg gggccataac gccaatcgtc
    19441 agaatgatta tcccgatact tagcccctgt ttttcaatcc acggaaaaaa ggtgcttaac
    19501 ggtgtgacgc ggacaatgat taacaccaga attgaaacgg cgacagtggt gttatgactg
    19561 ataaagccca gcgcagctaa cccgagcagg atcagcaaag tgacatcaaa catcgtggtt
    19621 tccttgccaa aaaataataa gcctgcttac tttacgcttg ctgcaggaag gaagtagaaa
    19681 atctttacgt tttttgcata aaaaatcagg cgaactgtca tcaaactgcc atttgtgcac
    19741 gctaacaata acgtgaaaac agctatctcc cgggggcatg ctatgaacga tcaaatgttt
    19801 gtcgagacac tgattatcac gtcatcgttt tttgccattg ctgttgtact ggttttgtcc
    19861 gttcttctta tcgaacggac cggctagtta cgcagtgcgg cggaaattga ccagttctgg
    19921 ttgcgcaatg cgcaaataat ccgcggtttt caaaataacg gatttatcca gcatgcctgc
    19981 attgaaggcg atttcatcaa atcgttcgaa gagtagaggg tcggcaacca gtttgagttt
    20041 tggatggaag ctgaaagggg ggatcgcgcc gaagacacag cctgtgagtt catcgacttc
    20101 cgccgggctg gccaacgaag cgcgtaatcc gcctatatgg ctggcgagtt ggctcagatc
    20161 ggcctgttga tcggctgcga ggatcgccag aacatgttga tttacgccat tgcctttgac
    20221 tttacatacc agtgccttag caccctggcc tagagcggtg ccacgaattt ctgacaccgc
    20281 ttcacattta cctaccgctt catgggtaac gacgcggaag tcagcacctt cttgtgataa
    20341 taaagcgatt aaccgctgat gcgtcacgct tcctttagcc atttcagtca tttcacgctc
    20401 ctgagattac aagcaaacaa ccacagaagg ttatcatgaa cggctgtttt tgttctgctt
    20461 attgacatat aaacgctcat cggaagcttt atacgcatca tgtaacgtat cgttttcttt
    20521 catcgcgtaa ataccggaag agaagccgat ctctttctgc ggcgcgatat gttgcagacg
    20581 tttttcgata cgttcaggca gttgtgctgc aatttgcggc gtcgaatcga caagaatgat
    20641 gcagaattca tcgccaccga gtcggatggc ataatcactt ttacgaatcg actgtttaat
    20701 cgcctgagct aataacgtaa tcgctaaatc cccctcctga tgaccgaggg tgtcatttat
    20761 ttgctttaac ttgtccatgt caatagcaat aaacatcacc gaagaaccgg attgcaccag
    20821 tttctgcaac cgctgctcca gttcaggggt taaaattttg cgattataca gtccagtcat
    20881 cgcatcacta atattttctc gcgacacatt ttggtataaa cggaagtgca tccgcaccat
    20941 attcagcaaa attaacgccg tcaaaatcca gaacagaacg cttttccacg aagacgtgat
    21001 aaagtaaaga atatcaatgg ataacgagac acgaatgccg cccggtaagt catggacgta
    21061 actgacatac tggaacagat tatcttcgct ctggttgatg ataatgtcgc gccccgaatc
    21121 ggtatcggtt agcgtgacat tgagaaaacg ccagaggaga gggcggtcat gagtataaaa
    21181 gatattccgc agattgtttt tgttaatatc cagcagcaca atccctttta gctgccctgc
    21241 gacatatacc ggcgtcagca aactcatcac gttctgttta gtacgctgat cctggtaaat
    21301 gctcgacaat acggtacgcc cggtaaatac cttttcaata tctttgcgat cgatgccaat
    21361 acttcctgac tgcaggaagg accagttatt catcgcaaag tattcaacat taaccggctc
    21421 ataaaaatag acatagcggt cattgagatc gagataatag tgaaatttct cttcggccat
    21481 cccaagacct gaaccgtaat catcctggtg gcggttgcct tccactgcct gatcaaaagc
    21541 gggtaatagt gctgcagctt ccacaattgt gtcgcagtca gtggatgcgg tttgtagtgt
    21601 gccgcgtaag cccgggtatt tatgggcagt caggtttaag ccatgggtgt tattggcaga
    21661 ctcaaaagcc tcgcagatgg cgcgccgctg ttctggcgac acttccgact gctcagcagc
    21721 gagagcgcgc atcacatgcg cggcaatact ctgattctga tacttatcat aaagaaagga
    21781 ggagtctgct ttctgcacga tatagcgcag ataggcactc attgctctgt cgctggcgac
    21841 aagttcaaaa ataaggaagg aagatgtcag cacaatgaca cttgcggcga taaaatgccg
    21901 gagcattcta tggtgcaatt tcatgataaa tggcactcct tcggttagtg aaacgagaaa
    21961 accagataaa gttcgattgc ggcctggcac aggggcgcta attatactca tctctgcgcc
    22021 gctggggagg ggaaatttag gggtaatagt aataaattgt atgcaaaagc cacgcaaaaa
    22081 gcatggctct gaatattttt gcacttaaat atgatgaata atcactttgt tgcccccctc
    22141 gcttttcgct tcgcgtaagg ctttatctgc ttccgtcatg acaagcgaga tattacgcgt
    22201 gtcacccgtt gaaaaaaccg tgccaatact gatggtcatt tgttcaggaa catcatatct
    22261 gttactaaag ccggtcagga gttcgacatt tttacgcata cgttccgcaa tgatttttgc
    22321 ctgggcacta ttgagttcgg taaatagcaa gccaaacacc tcaccctcca gtcgcgctaa
    22381 aatatcatcg gggcggatgc tttgctggat aatatcgaca attgaaacca gcactttatc
    22441 acccacacga tgtccccatt gggcattgat gcgtttgaac tgattaatat caaccagcat
    22501 gacacagaag tccttaacaa caggtcgcga caataatgac tctacgctgt tgaaaaagta
    22561 gcgccgatta taaatattgg tcagcacatc atgaactgcc agtttgctgg agagttgcag
    22621 ctcctgaaaa atgttataaa tcagaaaaga cacaacaaac agtttactgg aaacttcaat
    22681 cccgcgactg atataccaga tagtataatt atactcatcc agagtcagta gaagtaagtt
    22741 gcagcatagc gatgccagac ataataatgc tattaacggc catagttcgc tggctaatcg
    22801 tgtgcgcatg ataataaaga acagtaaaaa tgcccacaga caaaccaata tttttgtata
    22861 gttgattccc caggtcgcag tatggttgtc cggacagtaa tcgacgacat acaaagaata
    22921 gtcagcgtta taactgctca gattgtgtgc cagaagggga aaaactaaaa aagggatcag
    22981 cgccagcaac aggattcccg tttttttctt attgttgtca aggatgttgt cttttccata
    23041 acaaaagagc gccagcgagg ttaaacaaat aaaactgagt tggcggaaaa tatagaaaat
    23101 agaaacatca ttcgactttg tctggatcag tgtactgccg ttaattggtt tatggataat
    23161 tacaatggtt tcaactaaat agataaggcc acttaaaaat gcaaggctta aaatgagtgt
    23221 tggtaaaatt tgtttgttag tgaaatattt cattaacatg aaaagaaaaa tgacggcgtt
    23281 aaggaaaaac aaagccacaa caaccatcag gtaattcatc tgtgggatga gttttacatt
//
LOCUS       DAPOAV010000071        22731 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.071, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000071 DAPOAV010000000
VERSION     DAPOAV010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22731
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.071"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            126..1418
                     /gene="espX5"
                     /locus_tag="RN951_003162"
     CDS             126..1418
                     /gene="espX5"
                     /locus_tag="RN951_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="T3SS effector pentapeptide repeat protein EspX5"
                     /protein_id="HDX2528127.1"
                     /translation="MRYNGLNNMFFPLCLINDNHSVTSPSHTKKTKSDNYSKHHKNTL
                     IDNKALSLFKMDDHEKVIGLIQKMKRIYDSLPSGKITKETDRKIHKYFIDIASHANNK
                     CDDRITRRVYLNKDKEVSIKVVYFINNVTVHNNTIEIPQTVNGGYDFSHLSLKGIVIK
                     DEDLSNSNFAGCRLQNAIFQDCNMYKTNFNFAIMEKILFDNCILDDSNFAQIKMTDGT
                     LNSCSAMHVQFYNATMNRANIKNTFLDYSNFYMAYMAEVNLYKVIAPYINLFRADLSF
                     SKLDLINFEHADLSRVNLNKATLQNINLIDSKLFFTRLTNTFLEMVICTGSNMANVNF
                     NNANLSNCHFNCSVLTKAWMFNIRLYRVNFDEASVQGMGITILRGEENISINSDILVT
                     LQKFFEEDCATHTGMSQTEDNLHAVAMKITADIMQDAD"
     gene            complement(1572..3221)
                     /locus_tag="RN951_003163"
     CDS             complement(1572..3221)
                     /locus_tag="RN951_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter"
                     /protein_id="HDX2528128.1"
                     /translation="MEIFFTILIMTLVVSLSGVVTRVMPFQIPLPLMQIAIGALLAWP
                     TFGLHVEFDPELFLVLFIPPLLFADGWKTPTREFLEHGREIFGLALALVVVTVVGIGF
                     LIYWVVPGIPLIPAFALAAVLSPTDAVALSGIVGEGRIPKKIMGILQGEALMNDASGL
                     VSLKFAVAVAMGTMIFTVGGATVEFMKVAIGGILAGFVVSWLYGRSLRFLSRWGGDEP
                     ATQIVLLFLLPFASYLIAEHIGVSGILAAVAAGMTITRSGVMRRAPLAMRLRANSTWA
                     MLEFVFNGMVFLLLGLQLPGILETSLMAAEIDPNVEIWMLFTDIILIYAALMLVRFGW
                     LWTMKKFSNRFLKKKPMEFGSWTTREILIASFAGVRGAITLAGVLSIPLLLPDGNVFP
                     ARYELVFLAAGVILFSLFVGVVMLPILLQHIEVADHSQQLKEERIARAATAEVAIVAI
                     QKMEERLAADTEENIDNQLLTEVSSRVIGNLRRRADGRNDVESSVQEENLERRFRLAA
                     LRSERAELYHLRATREISNETLQKLLHDLDLLEALLIEENQ"
     gene            complement(3372..4721)
                     /gene="ghxP"
                     /locus_tag="RN951_003164"
                     /gene_synonym="yjcD"
     CDS             complement(3372..4721)
                     /gene="ghxP"
                     /locus_tag="RN951_003164"
                     /gene_synonym="yjcD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine/hypoxanthine transporter GhxP"
                     /protein_id="HDX2528129.1"
                     /translation="MSTPSARTGGSLDAWFKISQRGSTVRQEVVAGLTTFLAMVYSVI
                     VVPGMLGKAGFPPAAVFVATCLVAGLGSIVMGLWANLPLAIGCAISLTAFTAFSLVLG
                     QHISVPVALGAVFLMGVLFTVISATGIRSWILRNLPHGVAHGTGIGIGLFLLLIAANG
                     VGLVIKNPLDGLPVALGDFATFPVIMSLVGLAVIIGLEKLKVPGGILLTIIGISIVGL
                     IFDPNVHFSGVFAMPSLSDENGNSLIGSLDIMGALNPVVLPSVLALVMTAVFDATGTI
                     RAVAGQANLLDKDGQIIDGGKALTTDSMSSVFSGLVGAAPAAVYIESAAGTAAGGKTG
                     LTAITVGVLFLLILFLSPLSYLVPGYATAPALMYVGLLMLSNVAKIDFADFVDAMAGL
                     VTAVFIVLTCNIVTGIMIGFATLVIGRLVSGEWRKLNIGTVVIAVALVTFYAGGWAI"
     gene            complement(5267..5731)
                     /gene="soxR"
                     /locus_tag="RN951_003165"
     CDS             complement(5267..5731)
                     /gene="soxR"
                     /locus_tag="RN951_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensitive transcriptional activator SoxR"
                     /protein_id="HDX2528130.1"
                     /translation="MEKKLPRIKALLTPGEVAKRSGVAVSALHFYESKGLITSIRNSG
                     NQRRYKRDVLRYVAIIKIAQRIGIPLATIGEAFGVLPEGHTLSAKEWKQLSSQWREEL
                     DRRIHTLVALRDELDGCIGCGCLSRSDCPLRNPGDRLGEEGTGARLLEDEQN"
     gene            5817..6140
                     /gene="soxS"
                     /locus_tag="RN951_003166"
     CDS             5817..6140
                     /gene="soxS"
                     /locus_tag="RN951_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide response transcriptional regulator
                     SoxS"
                     /protein_id="HDX2528131.1"
                     /translation="MSHQKIIQDLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRT
                     VTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDLGYVSQQTFSRVFRRQFDRTPSD
                     YRHRL"
     gene            complement(6143..7729)
                     /gene="pdeC"
                     /locus_tag="RN951_003167"
     CDS             complement(6143..7729)
                     /gene="pdeC"
                     /locus_tag="RN951_003167"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="c-di-GMP phosphodiesterase PdeC"
                     /protein_id="HDX2528132.1"
                     /translation="MSHRARHQLLALPGIIFLVLFPIILSLWIAFLWAKSEVNNQLRT
                     FAQLALDKSELVIRQADLVSDAAERYQGQVCTPAHQKRMLNIIRGYLYINELIYARDN
                     HFLCSSLIAPVNGYTIAPADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVINPL
                     FWSEVMSDDPTLQWGVYDTVTKTFFSLSKEASAATFSPLIHLKDLTVQRNGYLYATVY
                     STKRPIAAIVATSYQRLITHFYNHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQ
                     RALEKHQLCLYYQPIIDIKTEKCIGAEALLRWPGEQGQIMNPAEFIPLAEKEGMIEQI
                     TDYVIDNVFRDLGDYLATHADRYVSINLSASDFHTSRLIARINQKTEQYAVRPQQIKF
                     EVTEHAFLDVDKMTPIILAFRQAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVE
                     TLTTHKTSHLIAEHIIELAHSLGLKTIAEGVETEEQVNWLRKRGVRYCQGWFFAKAMP
                     PQVFMQWMEQLPARELTRGQ"
     gene            8159..8440
                     /locus_tag="RN951_003168"
     CDS             8159..8440
                     /locus_tag="RN951_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjcB family protein"
                     /protein_id="HDX2528133.1"
                     /translation="MATLTTGVVLLRWQLLSAVMMFLASTLNIRFRRSDYVGLAVISS
                     GLGVVSACWFAMGLLGITMADITAIWHNIESVMIEEMNQTPPQWPMILT"
     gene            complement(8539..9075)
                     /gene="ssb1"
                     /locus_tag="RN951_003169"
     CDS             complement(8539..9075)
                     /gene="ssb1"
                     /locus_tag="RN951_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SSB1"
                     /protein_id="HDX2528134.1"
                     /translation="MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDK
                     ATGEMKEQTEWHRVVLFGKLAEVASEYLRKGSQVYIEGQLRTRKWTDQSGQDRYTTEV
                     VVNVGGTMQMLGGRQGGGAPAGGNIGGGQPQGGWGQPQQPQGGNQFSGGAQSRPQQSA
                     PAAPSNEPPMDFDDDIPF"
     gene            9329..12151
                     /gene="uvrA"
                     /locus_tag="RN951_003170"
     CDS             9329..12151
                     /gene="uvrA"
                     /locus_tag="RN951_003170"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDX2528135.1"
                     /translation="MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDT
                     LYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTIT
                     EIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
                     EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLA
                     ESFETALELSGGTAVVADMDDPKAEELLFSANFACPICGYSMRELEPRLFSFNNPAGA
                     CPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQMLKSLADHYKFDVEA
                     PWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSA
                     VREELAKFISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAG
                     QRAKIAEKILKEIGDRLKFLVNVGLNYLTLSRSAETLSGGEAQRIRLASQIGAGLVGV
                     MYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDIGPGAGV
                     HGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLK
                     DVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHF
                     DKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPESRARGYTPGRFSFNVRGGRC
                     EACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEARE
                     FFDAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYIL
                     DEPTTGLHFADIQQLLDVLHKLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGE
                     ILVSGTPETVAECEASHTARFLKPML"
     gene            complement(12186..12542)
                     /locus_tag="RN951_003171"
     CDS             complement(12186..12542)
                     /locus_tag="RN951_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HDX2528136.1"
                     /translation="MTISELLQYCMAKPGAEQSVHNDWKATQIKVEDVLFAMVKEVEN
                     RPAVSLKTSPELAELLRQQHSDVRPSRHLNKAHWSTVYLDGSLPDSQIYYLVDASYQQ
                     AVNLLPEEKRKLLVQL"
     gene            complement(12546..12962)
                     /locus_tag="RN951_003172"
     CDS             complement(12546..12962)
                     /locus_tag="RN951_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HDX2528137.1"
                     /translation="MWYQKTLTLSAKSRGFHLVTDEILNQLADMPRVNIGLLHLLLQH
                     TSASLTLNENCDPTVRHDMERFFLRTVPDNGNYEHDYEGADDMPSHIKSSMLGTSLVL
                     PVHKGRIQTGTWQGIWLGEHRIHGGSRRIIATLQGE"
     gene            complement(13073..13786)
                     /gene="aphA"
                     /locus_tag="RN951_003173"
     CDS             complement(13073..13786)
                     /gene="aphA"
                     /locus_tag="RN951_003173"
                     /EC_number="3.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HDX2528138.1"
                     /translation="MRKITQAISAVCLLFALNSSAVALASSPSPLNPGTNVARLAEQA
                     PIHWVSVAQIENSLAGRPPMAVGFDIDDTVLFSSPGFWRGKKTFSPESEDYLKNPVFW
                     EKMNNGWDEFSIPKEVARQLIDMHVRRGDAIFFVTGRSPTKTETVSKTLADNFHIPAT
                     NMNPVIFAGDKPGQNTKSQWLQDKNIRIFYGDSDNDITAARDVGARGIRILRASNSTY
                     KPLPQAGAFGEEVIVNSEY"
     gene            14188..14391
                     /locus_tag="RN951_003174"
     CDS             14188..14391
                     /locus_tag="RN951_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528139.1"
                     /translation="MNISYVNSNKTTSLPVELDALNNKDISYAKDFFLYIETQLKIAK
                     DFLDLEKKYQVLLQVKFFTHLLI"
     gene            complement(14893..16086)
                     /gene="tyrB"
                     /locus_tag="RN951_003175"
     CDS             complement(14893..16086)
                     /gene="tyrB"
                     /locus_tag="RN951_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transaminase"
                     /protein_id="HDX2528140.1"
                     /translation="MFQKVDAYAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIP
                     QLQAVAEAEARLNAQPHGASLYLPMEGLNCYRHAIAPLLFGADHPVLKQQRVATIQTL
                     GGSGALKVGADFLKRYFPESGVWVSDPTWENHVAIFAGAGFEVSTYPWYDEATNGVRF
                     NDLLATLKTLPARSIVLLHPCCHNPTGADLTNDQWDAVIEILKARELIPFLDIAYQGF
                     GAGMEEDAYAIRAIASAGLPALVSNSFSKIFSLYGERVGGLSVMCEDAEAAGRVLGQL
                     KATVRRNYSSPPNFGAQVVAAVLNDEALKASWLAEVEEMRTRILAMRQELVKVLSTEM
                     PERNFDYLLNQRGMFSYTGLSAAQVDRLREEFGVYLIASGRMCVAGLNTANVQRVAKA
                     FAAVM"
     gene            complement(16339..17418)
                     /gene="alr"
                     /locus_tag="RN951_003176"
     CDS             complement(16339..17418)
                     /gene="alr"
                     /locus_tag="RN951_003176"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDX2528141.1"
                     /translation="MQAATVVINRRALRHNLQRLRELAPASKMVAVVKANAYGHGLLE
                     TARTLPDADAFGVARLEEALRLRAGGITKPVLLLEGFFDARDLPTISAQHFHTAVHNE
                     EQLAALEEASLDEPVTVWMKLDTGMHRLGVRPEQAEAFYHRLTQCKNVRQPVNIVSHF
                     ARADEPKCGATEKQLAIFNTFCEGKPGQRSIAASGGILLWPQSHFDWVRPGIILYGVS
                     PLEDRSTGADFGCQPVMSLTSSLIAVREHKAGEPVGYGGTWVSERDTRLGVVAMGYGD
                     GYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGDPVILWGEGLPVERI
                     AEMTKVSAYELITRLTSRVAMKYVD"
     gene            complement(17471..18886)
                     /gene="dnaB"
                     /locus_tag="RN951_003177"
     CDS             complement(17471..18886)
                     /gene="dnaB"
                     /locus_tag="RN951_003177"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HDX2528142.1"
                     /translation="MAGNKPFNKQQAEPRERDPQVAGLKVPPHSIEAEQSVLGGLMLD
                     NERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGG
                     FAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDL
                     AESRVFKIAESRANKDEGPKNIADVLDATVARIEQLFQQPHDGVTGVNTGYDDLNKKT
                     AGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASL
                     SRVDQTKIRTGQLDDEDWARISGTMGILLEKRNIYIDDSSGLTPTEVRSRARRIAREH
                     GGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQR
                     ADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVR
                     LTFNGQWSRFDNYAGPQYDDE"
     gene            18969..19952
                     /locus_tag="RN951_003178"
     CDS             18969..19952
                     /locus_tag="RN951_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone oxidoreductase"
                     /protein_id="HDX2528143.1"
                     /translation="MATRIEFHKHGGPEVLQAVEFTPADPAENEIQVENKAIGINFID
                     TYIRSGLYPPPSLPSGLGTEAAGIVSKVGSGVKHIKAGDRVVYAQSALGAYSSVHNII
                     ADKAAILPAAISFEQAAASFLKGLTVYYLLRKTYEIKPDEQFLFHAAAGGVGLIACQW
                     AKALGAKLIGTVGTAQKAQSALKAGAWQVINYREEDLVERLKEITGGKKVRVVYDSVG
                     RDTWERSLDCLQRRGLMVSFGNSSGAVTGVNLGILNQKGSLYVTRPSLQGYITTREEL
                     TEASNELFSLIASGVIKVDVAEQQKYPLKDAQRAHEILESRATQGSSLLIP"
     gene            complement(20118..20360)
                     /gene="pspG"
                     /locus_tag="RN951_003179"
     CDS             complement(20118..20360)
                     /gene="pspG"
                     /locus_tag="RN951_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313059.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response protein PspG"
                     /protein_id="HDX2528144.1"
                     /translation="MLELLFVIGFFVMLMVTGVSLLGIIAALVVATAIMFLGGMLALM
                     IKLLPWLLLAIAVVWVIKAIKAPKVPKYQRYDRWRY"
     gene            complement(20494..21531)
                     /gene="dusA"
                     /locus_tag="RN951_003180"
     CDS             complement(20494..21531)
                     /gene="dusA"
                     /locus_tag="RN951_003180"
                     /EC_number="1.3.1.-"
                     /EC_number="1.3.1.91"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(20/20a) synthase DusA"
                     /protein_id="HDX2528145.1"
                     /translation="MHGNSEMQKINQTSAMPEKTDVHWSGRFSVAPMLDWTDRHCRYF
                     LRLLSRNTLLYTEMVTTGAIIHGKGDYLAYSEEEHPVALQLGGSDPAALAQCAKLAEA
                     RGYDEINLNVGCPSDRVQNGMFGACLMGNAQLVADCVKAMRDVVSIPVTVKTRIGIDD
                     QDSYEFLCDFINTVSGKGECEMFIIHARKAWLSGLSPKENREIPPLDYPRVYQLKRDF
                     PHLTMSINGGIKSLEEAKAHLQHMDGVMVGREAYQNPGILAAVDREIFGSSDTDADPV
                     AVVRAMYPYIERELSQGTYLGHITRHMLGLFQGIPGARQWRRYLSENAHKAGADINVL
                     EHALKLVADKR"
     gene            complement(21894..22731)
                     /locus_tag="RN951_003181"
                     /pseudo
     CDS             complement(21894..22731)
                     /locus_tag="RN951_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001560258.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="DUF2713 domain-containing protein"
BASE COUNT         6075 a         5753 c         5363 g         5540 t
ORIGIN      
        1 gcatcacctt ttcccataat attaaacaaa taaactcatt aaaaaatgag cgatttttga
       61 cagtcgtaga aaatgataat gcagagaata tgccttttct ttcttgttaa ttataaggat
      121 attttatgcg ctataatggt ttaaataata tgtttttccc tctttgcctg attaacgata
      181 accactctgt cacaagtcca tcacatacaa agaaaacaaa atcagataat tacagcaaac
      241 atcataaaaa cacgttaatt gacaataaag ccctctctct tttcaaaatg gatgatcatg
      301 aaaaagtgat aggcttgatt cagaaaatga aaagaattta tgatagttta ccatcaggaa
      361 aaatcacgaa agaaacggac aggaaaatac ataaatattt tatagatata gcttcacatg
      421 caaataataa atgtgacgat agaattacga gaagagttta ccttaataaa gataaggaag
      481 tgtcaattaa ggtggtatat tttataaata atgtcaccgt ccataataat actatcgaaa
      541 tcccacagac agtaaatggt ggttacgatt tttcacacct tagcctgaaa ggtatcgtga
      601 ttaaagatga agatttatcc aattcgaatt ttgcaggttg cagactacaa aacgctattt
      661 ttcaggactg taatatgtat aaaacgaatt ttaatttcgc cataatggaa aaaatacttt
      721 ttgataattg tattctcgat gactcaaatt tcgctcagat aaaaatgact gacggaactc
      781 taaattcatg ttccgctatg catgttcaat tctacaatgc aacaatgaat agagccaata
      841 ttaaaaatac cttccttgat tattcaaatt tttatatggc atacatggct gaggtaaatc
      901 tttataaagt aatagcgcca tatattaatt tatttagagc cgaccttagc ttctctaaac
      961 ttgatttaat taactttgaa catgctgatc tgtctcgtgt caacctgaat aaagcaaccc
     1021 tccagaatat aaacttaatt gatagcaaac tcttttttac gcggttaaca aatacgttcc
     1081 tcgaaatggt tatatgtacc ggctctaata tggctaatgt taattttaat aatgccaatt
     1141 taagcaattg ccatttcaac tgttctgttt taacaaaagc ctggatgttt aatatccgtc
     1201 tctatcgtgt taatttcgat gaggctagcg tccagggaat gggtattacc attctccgtg
     1261 gtgaggaaaa tatctccatt aatagtgata tcctggtaac actacagaaa ttctttgaag
     1321 aagattgtgc cactcatact ggcatgtcac aaactgagga taatcttcat gcagtcgcta
     1381 tgaagattac tgcagatatt atgcaagatg cagattgagg ttaagtcgaa gaacagccaa
     1441 tgaattgact ttaaaagaga gataacttat ttgttttaga atcatgaatg ttagcccgag
     1501 ctaacctgtt aaaggtgcaa aagattgcac ctttttcaga ttacctcggg cctggttacg
     1561 tcgctttcgg cttactgatt ttcctcaatt agcaacgctt caagcaaatc gagatcgtgc
     1621 agtaattttt gcagcgtttc gttgctgatc tcccgtgtgg cgcgcaggtg gtaaagttca
     1681 gcacgttcag aacgcaatgc cgccagacgg aagcgacgct caaggttctc ttcctgcacg
     1741 gaactttcaa cgtcgttacg tccatcggcg cgacgacgca ggttaccaat gacgcgagaa
     1801 ctgacctccg taagcagctg gttatcgata ttctcttcgg tatccgccgc cagacgctcc
     1861 tccattttct ggatcgccac aatcgccact tctgccgttg ccgctcgcgc aatacgttcc
     1921 tctttcaatt gttgcgaatg atccgcgact tcaatgtgtt gtagcagaat aggcaacatc
     1981 accacgccga caaacagcga gaagagaatg acgccagccg ccaggaacac cagctcatag
     2041 cgcgccggga agacgttacc atccggcaag agcagcggga tagagagcac accggccaga
     2101 gtgatcgccc cacgcacccc ggcgaaagac gcgatcagga tttctcgtgt ggtccacgaa
     2161 ccaaactcca tcggcttctt cttcaggaag cggttgctga actttttcat cgtccacagc
     2221 cagccgaaac ggaccagcat cagcgccgca tatatcagaa taatatcggt aaacagcatc
     2281 cagatttcga cgttagggtc gatttctgct gccatcagcg acgtctccag aatacccggc
     2341 agctgcagac ctaacagcag gaacaccatg ccgttaaaga caaattccag catcgcccag
     2401 gtgctgtttg cacgcaggcg cattgccagc ggcgcacggc gcatcacacc ggagcgggtg
     2461 atggtcatcc cggcggcaac cgcagcgagg atgccggaaa cgccaatatg ttcggcaatc
     2521 agataagaag cgaatggcag caggaacagc aggacgatct gcgtcgcggg ttcatcaccg
     2581 ccccagcggc tgaggaatcg cagcgagcga ccgtacagcc agctcaccac aaaaccggcg
     2641 agaataccgc caatggctac tttcataaat tcgaccgtcg caccgccgac ggtgaagatc
     2701 atcgtcccca tcgccactgc tacggcaaac ttcaacgaca ccagaccgga ggcgtcattc
     2761 atcaacgctt cgccctgcaa aatgcccatg atttttttcg ggatgcgccc ttcgccaaca
     2821 atcccggaga gcgccacagc atcggtcgga gaaagcaccg ccgccagcgc aaaggcaggg
     2881 atcagcggaa tgcccggcac cacccagtaa ataaggaagc caatgccgac cacggtgacc
     2941 accaccagcg ccagcgcgag gccgaaaatc tctcgaccat gttcgagaaa ttcacgggtc
     3001 ggcgttttcc agccgtcagc gaacagcaac ggcgggataa acaagactaa aaagagttca
     3061 ggatcaaact ccacatgcaa accaaacgtc ggccacgcca gtagcgcacc gatggcgatt
     3121 tgcataagcg gaagcgggat ctgaaagggc atgacacgag tgaccacccc ggacagcgag
     3181 accacgaggg tcattatcag tatggtgaag aagatttcca tgcgttccct gtttgcgatg
     3241 ttttttatga tctgagaaag acgttatgcc tgaattctca ttttttcaga atatcgcaaa
     3301 agctcacaca atgtgcggag aaaataaaaa cgggcagcca ttgccacccg ttttcagaat
     3361 ccgatgaaag attagatagc ccagccaccc gcatagaagg tcaccagcgc cacggcgata
     3421 acgaccgtac cgatgttcaa cttgcgccat tcgccggaaa ccagacgacc aatcaccaga
     3481 gtcgcgaagc cgatcatgat gcctgttacg atgttacagg tcagcacgat gaatacagcc
     3541 gtaaccagac ccgccatcgc atcaacaaaa tcagcaaagt cgattttcgc cacgttgctc
     3601 agcatcagca ggccaacgta catcagcgcc ggagccgttg cataccccgg aacgaggtaa
     3661 gagagcggag agaggaacag aatcaggagg aacagcacgc caacggtgat agccgtcaaa
     3721 ccggttttac cgcccgccgc cgtacccgcc gcagactcga tgtataccgc tgccggagcc
     3781 gcacccacca ggccagagaa aacgctgctc atggagtcag tggtcagtgc tttcccaccg
     3841 tcgatgatct gcccatcttt atccagcagg ttcgcctggc cggcgacggc acggatagtt
     3901 ccggtggcat caaatactgc cgtcatcacc agcgccagaa cgcttggcag gactacagga
     3961 ttcagcgcgc ccataatgtc caggctgcca atcagtgaat tgccgttttc atcgctcaat
     4021 gaaggcatgg cgaaaacgcc ggagaaatgg acgttaggat cgaagatcaa accgacaatt
     4081 gagataccga taatggtcag cagaatgcca ccagggactt tcagtttttc caggccgatg
     4141 atcaccgcca gacctaccag tgacataatc accgggaagg tcgcgaaatc acccagcgca
     4201 acgggcagac catcaagcgg gtttttaatc accagaccga caccgttagc ggcaatgagc
     4261 agcaggaaca gaccgatacc aatccccgtg ccgtgcgcca caccgtgagg caagttgcgc
     4321 aaaatccagc tacggatacc cgtggcagaa attaccgtaa acagcacacc catcaggaac
     4381 acggcaccca gcgcgacagg tacgctaata tgttgcccca gcaccaggct gaatgcggta
     4441 aacgctgtca gggagatggc gcaaccaatc gccaacggca gattagccca cagacccatc
     4501 acgatagaac cgagtccggc aaccagacag gttgcaacga aaactgccgc aggcgggaag
     4561 cctgctttac ccaacatacc tggaacgacg atgaccgagt agaccatcgc cagaaacgtt
     4621 gttaacccgg caaccacttc ctgacggaca gtgcttccac gttgtgaaat tttaaaccag
     4681 gcgtcgagtg aaccgccggt acgcgctgat ggcgtagaca taagaaaaca tcccctgaga
     4741 gtttaatttt cgtcaagatg cgtggcggac aatcccctgc cagcgaaacg ttatcttcct
     4801 gctccaggtt tgcgacaatt tgctgcgtcg caaaaaagca aacgtttagc tccgcgcata
     4861 caaaacgggt ggtaaaaaaa gcaaacgatt atccggcgat catagcggct ttttcaaccg
     4921 aagtttgctg cttttttctc ttttattgtc ttgacgatga aaaaccaggc aattgatgcg
     4981 caaacgttat cgtcggtgcg caagattgca gcgttatcga gccgtatacc gttcaggatt
     5041 gcgataaaaa atcgtctgag atgacaaaaa tattgcggtt aaaaagtata cttttacact
     5101 ggcgaagaaa cgtcggtgac atacaattaa agcatcaaca ccaaccggaa cctccaccac
     5161 gtgctcgaat gaggtgtgtt gacgtcgggg gaaaccctcc tgtgtaccag cgggatagag
     5221 agaaagacaa agaccggaaa acaaactaaa gcgcccttgt ggcgctttag ttttgttcat
     5281 cttccagcaa gcgtgcgccg gtaccttctt ctcctaagcg gtcgcccggg ttacgcaacg
     5341 ggcaatcact gcgcgaaagg cagccacaac caatacatcc gtccagttcg tcacgcagcg
     5401 ccactaaggt atgaatgcgc cgatccaact cttctcgcca ttgggacgaa agctgtttcc
     5461 actctttcgc acttaacgta tgcccttcgg gcaacacgcc aaacgcttca ccaatggtcg
     5521 ccagcggaat gccaatacgc tgagcaattt tgataattgc aacatatcgc aacacatcac
     5581 gtttatatcg ccgctgattg ccgctgttac ggatactggt aatcaaccct ttactttcat
     5641 agaaatgcag cgccgatacc gccacaccgc tgcgtttcgc cacttcgccg ggggttagca
     5701 gcgctttaat gcggggtaat ttcttttcca taaatcgctt tacctcaagt taacttgagg
     5761 aattatactc cccaacagat gaattaacga actgaacact gaaaagaggc agatttatgt
     5821 cccatcagaa aattattcag gatcttatcg catggattga cgagcatatt gaccagccgc
     5881 ttaacattga tgtagtcgca aaaaaatcag gctattcaaa gtggtacttg caacgaatgt
     5941 tccgcacggt gacgcatcag acgcttggcg attacattcg ccaacgccgc ctgttactgg
     6001 ccgccgttga gttgcgcacc accgagcgtc cgatttttga tatcgcaatg gacctgggtt
     6061 atgtctcgca gcagaccttc tcccgcgttt tccgtcggca gtttgatcgc actcccagcg
     6121 attatcgcca ccgcctgtaa ttttattgcc cgcgcgttaa ctcccgcgcg ggtaattgct
     6181 ccatccattg cataaacacc tgcggcggca tcgccttcgc aaagaaccat ccctggcaat
     6241 agcgcacgcc gcgtttgcgc agccagttaa cctgctcctc agtttcgacg ccttcagcga
     6301 tcgtttttaa ccccaggctg tgcgccagct cgatgatgtg ttccgcaatc aaatgactgg
     6361 ttttgtgggt ggtcagcgtt tcaacaaacg atttgtcgat tttcaaaata tcgacattca
     6421 atgatttaag gttatgcaag ttagagtagc caataccaaa atcatcaatt gccacttcgt
     6481 aacctgcctg gcggaaagcc agaataatcg gcgtcatttt gtcaacatca agaaatgcat
     6541 gctcagtcac ttcaaattta atttgctgcg gacgcaccgc gtattgctct gttttctgat
     6601 tgattcgcgc tatcaaccgt gacgtatgaa aatcggaggc cgacaggtta atagaaacat
     6661 agcgatctgc atgtgttgcc aggtaatcgc ccagatcgcg gaagacatta tcaataacat
     6721 aatcagttat ctgttctatc atcccctcct tttctgccag cggaataaac tctgccggat
     6781 tcattatttg cccctgctca ccaggccaac gtaacaacgc ttcagcgccg atacattttt
     6841 ctgttttgat atcgattatt ggctggtaat aaagacaaag ttgatgtttt tcgagggcgc
     6901 gttgcaattt acgtttggga gataaatagt tttgtcgaat acgtagccag agtaatagca
     6961 gaacaagact ccccaaaata ccggcgggca acgcaaaaat aagatgatta taaaaatggg
     7021 ttataagacg ttgatatgaa gtcgcaacaa tggctgcaat tgggcgtttt gtcgaataaa
     7081 ctgtcgcata taaatagcca tttctttgta cggttaaatc cttcaaatga atcagcggag
     7141 aaaacgttgc tgccgaggcc tctttgctta acgagaaaaa ggttttcgtc accgtatcat
     7201 acacacccca ttgcaatgtc gggtcatcag acatcacttc actccagaag agagggttga
     7261 taaccgccac ataatttccc cgctgcatat aggtcatttt atagccagag aaaaaaggcg
     7321 tatcgcggta ataatagata gaaacgttag gttcacgctt ataatcggcc ggtgcaatcg
     7381 tatagccgtt tacaggcgct atcagcgatg agcataaaaa atggttatca cgggcataga
     7441 tcaattcatt aatataaaga tagccacgaa taatattcaa cattcgcttt tgatgggctg
     7501 gagtgcaaac ttgcccctga tagcgttcag ctgcatcgct cactaaatct gcctggcgaa
     7561 tgaccagctc ggatttatcc agtgccagtt gagcaaaggt tcggagctga ttattcactt
     7621 ctgattttgc ccaaaggaag gcaatccata gcgaaagaat gatgggaaag agaactaaaa
     7681 agataatgcc cggcaacgcc agtaattggt gtcgtgcacg atgactcatt gctatcaatt
     7741 tcctgcctgt ttatacccgg ccattgcaag gtgaaaaccc tgggtaccga cgtctttaga
     7801 taaatcttac ggtataaata gcacttttgc ctgatttgaa attgatacct ttctaatcgt
     7861 cacctggatg aaaataattc attgatattc aaaattaatt tcctacagga atgcagaggc
     7921 ggcgggaaga tatgccctta atgccactga aaaaccacat aatctgtaca gcaataaaag
     7981 tcacggccta atatggctaa caaacaatca attgtgatat agttcacaaa attaatgaaa
     8041 caaacagagt gtttcatttt tgtgttctgc aagccccgcg atagccagag tgtaccacgc
     8101 ctcccgtgaa caacgccgcg ctgtccaggg catcggctct tttcagagga attgtttgat
     8161 ggctaccctc accactggcg tggttcttct tcgctggcaa cttcttagtg ccgtaatgat
     8221 gtttctggcc agcacactca acatccgttt tcgtcggtct gattatgtcg ggcttgcggt
     8281 gatcagcagc ggtctgggcg ttgtttccgc ctgttggttc gcaatggggt tgcttggcat
     8341 cacaatggcg gacatcaccg ctatctggca caacatcgag tcggtgatga tagaagagat
     8401 gaatcagaca ccgccacaat ggccaatgat tttgacctga tacgtagaag cctccataac
     8461 ggaggcttct tttttatggc tggcagatgc tttaatcatc caccttaaaa caatataacc
     8521 tattgtttta atgacaaatc agaacggaat gtcatcatca aagtccatcg gcggctcgtt
     8581 agacggcgct gccggagcgg actgctgcgg gcgagactgc gcgccgccgc tgaactgatt
     8641 gccaccctgc ggctgctgag gctgacccca accgccctgc ggctgaccac caccgatatt
     8701 gccacctgcc ggagcgccac caccctgacg accacccagc atctgcatgg tgccgccaac
     8761 gttcaccacg acttctgtgg tgtagcgatc ctgaccggat tgatcggtcc atttacgggt
     8821 acgcagctga ccttcgatat aaacctgaga acctttacgc agatattcgc tcgccacttc
     8881 tgccagtttg ccgaacagca caacgcggtg ccattcagtc tgttctttca tctcgccggt
     8941 cgctttatca cgccaggatt cggaagtagc cagcgtaatg ttggcaactg cgccaccatt
     9001 tggcatgtag cgtacttccg ggtcctgacc cagattacca acgagaataa ccttgtttac
     9061 gcctctgctg gccatgttcg tgtctcctga aaaaaatcgt tctgaataag tgtaaacgcg
     9121 cgattgtacc attaccaata gcgcttttac tatgttgtga cctcggttcc gggaaacaaa
     9181 cctggccaga cattgttaca caacactccg ggtaatgcat tccaatactg tatattcatt
     9241 caggtcaatt tgtgtcataa ttaaccgttt gtgatcgccg gtagcaccat gccaccgggc
     9301 aaaaaagcgt ttaatccggg aaaggtgaat ggataagatc gaagttcggg gcgcccgcac
     9361 ccataatctc aaaaacatca acctcgttat cccccgcgac aagctcattg tcgtgaccgg
     9421 gctttcgggt tctggcaaat cctcgctcgc tttcgacacc ttatatgccg aagggcagcg
     9481 ccgttacgtt gaatcccttt ccgcctacgc gcggcagttt ctgtcactga tggaaaagcc
     9541 ggacgtcgat catattgagg ggctttctcc tgccatctca attgagcaga aatcgacgtc
     9601 tcataacccg cgttctacgg tggggacaat caccgaaatc cacgactatt tgcgtttgtt
     9661 attcgcccgc gttggcgagc cgcgctgtcc ggaccacgac gtcccgctgg cggcgcaaac
     9721 cgtcagccag atggtggata acgtgctgtc gcagccggaa ggcaagcgtc tgatgctact
     9781 cgcgccaatc attaaagagc gcaaaggcga acacaccaaa acgctggaga acctggcaag
     9841 ccagggctac atccgtgctc gtattgatgg cgaagtctgc gatctttccg atccgccaaa
     9901 actggaactg caaaagaaac ataccattga agtggtggtt gatcgcttca aggtgcgtga
     9961 cgatcttacc caacgtcttg ccgagtcatt tgaaaccgcg ctggagcttt ccggtggtac
    10021 cgcggtagtg gcggatatgg acgacccgaa agcggaagag ctgctgttct ccgccaactt
    10081 cgcctgccca atttgcggct acagtatgcg tgaactggag ccgcgactgt tttcgtttaa
    10141 caacccggcg ggggcctgcc cgacctgcga cggccttggc gtacagcaat atttcgatcc
    10201 tgatcgagtg atccagaatc cggaactgtc gctggctggt ggtgcgatcc gtggctggga
    10261 tcgccgcaac ttctattatt tccagatgct gaaatcgctg gcagatcact ataagttcga
    10321 cgtcgaagcg ccgtggggca gcctgagcgc gaacgtgcat aaagtggtgt tgtacggttc
    10381 tggcaaagaa aacattgaat tcaaatacat gaacgatcgt ggcgatacct ccattcgtcg
    10441 tcatccgttc gaaggcgtgc tgcataatat ggagcgccgc tataaagaga cggaatccag
    10501 cgcggtacgc gaagaattag ccaagtttat cagtaatcgt ccgtgcgcca gctgcgaagg
    10561 gacgcgtctg cgtcgggaag cgcgccacgt gtatgtcgag aatacgccgc tgcctgctat
    10621 ctccgacatg agcattggtc atgcgatgga attcttcaac aatctcaaac tcgcaggtca
    10681 gcgggcgaag attgcagaaa aaatccttaa agagatcggc gatcgtctga aattcctcgt
    10741 taacgtcggc ctgaattacc tgacgctttc ccgctcggca gaaacgcttt ctggcggtga
    10801 agcacagcgt atccgtctgg cgagccagat tggtgcgggc ctggttggcg ttatgtacgt
    10861 gctggacgag ccgtctatcg gcctgcacca gcgtgataac gagcgcctgt tgggtacgct
    10921 tatccatctg cgcgatctcg gtaataccgt gattgtggtg gagcacgacg aagacgcaat
    10981 tcgcgccgct gaccatgtga tcgacattgg cccgggcgca ggtgttcacg gcggtgaagt
    11041 ggtcgcagaa ggtccgctgg aagcgattat ggcggtgccg gagtcgttga ccgggcagta
    11101 catgagcggc aaacgcaaga ttgaagtgcc gaagaaacgc gttccggcga atccggaaaa
    11161 agtgctgaag ctgacaggcg cacgcggcaa caacctgaag gacgtgacgc tgacgctgcc
    11221 ggtgggtctg tttacctgca tcaccggggt ttcaggttcc ggtaaatcga cgctgattaa
    11281 cgacacactg ttcccgattg cccaacgcca gttgaatggg gcgaccatcg ccgaaccagc
    11341 accgtatcgc gatattcagg ggctggagca tttcgataaa gtgatcgata tcgaccaaag
    11401 cccaattggt cgtactccac gttctaaccc ggcgacctat accggcgtgt ttacgcctgt
    11461 gcgcgaactg tttgcgggcg taccggaatc ccgtgcgcgc ggctatacgc cgggacgttt
    11521 cagctttaac gttcgtggcg gacgctgcga ggcctgtcag ggcgatggcg tgatcaaagt
    11581 ggagatgcac ttcctgccgg atatctacgt gccgtgcgac cagtgcaaag gtaaacgcta
    11641 taaccgtgaa acgctggaga ttaagtacaa aggcaaaacc atccacgaag tgctggatat
    11701 gaccatcgaa gaggcgcgtg agttctttga tgccgtacct gcactggcgc gtaagctgca
    11761 aacgttgatg gacgttggcc tgacgtacat tcgactgggg cagtccgcaa ccaccctttc
    11821 aggcggtgaa gcccagcgcg tgaagctggc gcgtgaactg tcaaaacgcg gcaccgggca
    11881 gacgctgtat attctcgacg agccgaccac cggtctgcac ttcgccgata ttcagcaact
    11941 gctcgacgta ctgcataaac tgcgcgatca gggcaacacc attgtggtga ttgagcacaa
    12001 tctcgacgtg atcaaaaccg ctgactggat tgtcgacctg ggaccagaag gcggcagtgg
    12061 tggcggcgag atcctcgtct ccggtacgcc agaaaccgtc gcggagtgcg aagcatcaca
    12121 cacggcacgc ttccttaagc cgatgctgta atcgttaagg ccgctttctg agcggccttt
    12181 tcctttcaga gttgcaccag caatttacgt ttttcttccg gcagtaaatt caccgcctgc
    12241 tgataagacg catccaccag ataatagatt tgcgaatctg gcagcgaacc gtcgagatac
    12301 acggtgctcc agtgcgcttt attcagatgg cggcttggac gcacatcgct gtgctgctga
    12361 cgtagcagct ccgccagctc cgggctggtt ttcagcgaaa cagctgggcg attttctact
    12421 tctttcacca tcgcaaacag tacatcttcc actttgatct gcgtcgcttt ccagtcatta
    12481 tgcacgctct gttctgcgcc tggttttgcc atgcaatatt gtagcaactc cgaaatggtc
    12541 attttttact ccccttgtag tgtcgcgatg atgcgacgcg atccgccgtg gatgcgatgt
    12601 tcccccagcc aaatgccttg ccaggtgccg gtctgaatac gccctttatg caccggcaat
    12661 acaagcgatg ttcccagcat tgaggatttg atatgagaag gcatatcgtc tgctccctca
    12721 tagtcatgct cataatttcc gttgtcggga acggtgcgga ggaaaaaacg ctccatgtcg
    12781 tggcgtacgg tgggatcgca gttctcatta agtgtcagag aggcggaggt atgttgcagc
    12841 aacagatgca gtaagccgat gttaacgcgc ggcatatcag ccagctgatt cagaatttca
    12901 tccgttacca gatgaaaccc acgagatttg gcgctaagcg tgagcgtctt ttgataccac
    12961 atgtgctgct ccttgataaa actctcttaa tcagtttgca gcaagacagc gaaaggataa
    13021 aggtgtgatt aaaaaaacag cattcgggag agcatcacgc tctcccgctc tgtcagtatt
    13081 ctgaattgac gatcacctct tcaccaaacg cacccgcttg tggcaagggt ttgtaggtag
    13141 agttggaggc gcgcagaatg cggataccac gagcgccgac atcgcgtgcg gcggtaatat
    13201 cattatcaga atcgccataa aaaattcgga tatttttatc ctgcagccat tgcgattttg
    13261 tattttgccc tggtttatcg cccgcaaaga tcaccggatt catgttggtg gcaggaatat
    13321 gaaaattatc cgccagcgtt tttgaaaccg tttctgtttt cgtcgggcta cgaccagtca
    13381 caaagaagat cgcgtcaccg cggcgtacat gcatatcaat cagctggcga gcgacctctt
    13441 ttggaatgct gaattcatcc cagccattgt tcattttttc ccagaacaca ggatttttca
    13501 gataatcttc gctttctggc gagaaggttt ttttgccgcg ccagaagccc ggactggaaa
    13561 aaagtaccgt gtcatcgata tcaaacccca ccgccattgg cggacgccct gcgaggctat
    13621 tttcaatttg tgcgaccgaa acccaatgaa tgggtgcctg ttcagcaagc ctggcaacgt
    13681 tagtcccagg gttaagcggt gaaggagatg aggccagggc aacagcggaa ctgtttagag
    13741 cgaacaataa gcaaacggca ctgattgcct gtgtgatctt gcgcatattt ttccctaaat
    13801 agtcagtatg ttgaaacttt ttattgtgag atttgttgca aaaaccatct gaccataacg
    13861 ccagctgccg gggaaaggaa ggattatctg cggtttttgt gatgaaaagc aggatgatta
    13921 tatttaaccc agtaaatacg ttcctgtctt tttttgtata aaaaatgttt attactcgat
    13981 gtaaggatac attaatttta cgtttattat gatgaatcct cggcaaatga gcgaaatttg
    14041 atagaacatt tatctgctgt acgatttaat gaacttaatg atacagcatt acaaaaacaa
    14101 tcgaagttta taaagatgat ttctgattga ccagccccct accctacaat ggtgattaat
    14161 tttattactc gcgatggaga tgatgatatg aatatatcat atgtgaatag caacaaaacg
    14221 acatctttac ctgttgagct agatgcacta aataataaag atatctctta tgccaaagat
    14281 ttctttttat acatagaaac acagttaaaa attgcaaaag attttttaga cctggagaag
    14341 aagtatcaag ttctattgca agtaaagttt ttcacgcatt tattgattta gttaacaaaa
    14401 tcaggggtaa gaaagacttt atgtatattt gcacgctttg ctgttttgcc gaggaggtta
    14461 aaggtgatta ttctcattac aggacctttt tatttgatat tggtaatcaa tataaggtta
    14521 aacttacaca aagcggaaaa aagagttctc tttaacatta gaatttaacg atactataat
    14581 tgaatctcag aaagtcacag gcaataaggc aaagcatatt cttgaggata tagaaatatt
    14641 ctatcgtaac aaacccgata cttattatta aatttaataa tggttagatg tgcagaaatt
    14701 attactccac ccaaaaaaac aggataagga attccagata attgggataa gcttaacaat
    14761 aaaagaacta acaacgttta ttatctctca cgtagaacga tggcatcaaa aaaatcatct
    14821 ataaagaaag agtgaaagcg acgacagttt aatttcactg caggctgggt agctccagcc
    14881 tgctttcctg cattacatca ccgcagcaaa cgcctttgcc acacgttgta catttgccgt
    14941 atttaacccg gcgacacaca tgcgaccgct ggcgatgaga tagacaccaa attcttcacg
    15001 tagtcggtca acctgagcgg cacttaaacc ggtataactg aacatgccgc gctgattaag
    15061 cagataatcg aaattgcgtt ctggcatctc tgtgcttaat accttcacca attcctgacg
    15121 cattgccaga atgcgagtac gcatctcttc tacttccgcc agccagctgg ctttcaatgc
    15181 ctcgtcattc agcactgcag ccaccacctg cgcaccaaaa ttcggcgggc tggagtagtt
    15241 gcggcgaact gttgctttca attgccccag tacgcggcca gcggcttcgg catcttcaca
    15301 cataacagaa agtccgccga cgcgctcgcc gtaaagggag aaaattttcg agaacgaatt
    15361 gctcaccaga gcgggtaatc cagcgctggc aatggcgcga atagcgtagg catcctcttc
    15421 cataccggca ccaaatcctt gataggcaat atcgaggaat ggaataagct cgcgggcttt
    15481 gagaatttca atcaccgcat cccactgatc attagtgaga tcggcacccg ttgggttgtg
    15541 gcaacatgga tgcagcaaca caatactgcg ggcaggtaat gttttcagcg tcgccaacag
    15601 gtcattaaag cgcacgccgt tagtcgcttc gtcataccag gggtaagtac tcacttcgaa
    15661 tccagccccg gcgaatattg ctacgtggtt ttcccaggta ggatcgctga cccagacgcc
    15721 tgattccggg aagtagcgtt tcaggaaatc cgcgcccact ttcaatgccc cggagccgcc
    15781 aagggtttga atggttgcta cgcgctgttg tttcagtacc ggatggtccg caccaaacag
    15841 cagcggcgca atggcatggc gatagcagtt aagcccttcc atcggtaaat aaagcgaagc
    15901 gccatgaggc tgcgcattca ggcgcgcttc cgcctccgcc acggcttgca gttgtggaat
    15961 aattccgtct tcgttgtagt acagaccgat acttaaattc actttgtcgc tgcgagggtc
    16021 ttctttaaaa cgctccataa gcgtaagaat cgggtcgcca gcgtaggcgt caactttttg
    16081 aaacacgcga tggttctcca ggtttacggg caggtggtta aaacacaata aaccggaaga
    16141 aggcgaagat cgagtggatg ttcaggagcg aacggcaatt agcaacagag tgagactcat
    16201 gacaaacgta catccgccag aggcacgacc tttataagag catgaaagaa catcaactta
    16261 ttgaattttt aggattttat tggccggata aggcattcac gccgcatccg gcacagacaa
    16321 tcaaatatta cagaacgatt aatccacgta tttcatcgcg acccttgaag tcaggcgcgt
    16381 aataagttcg taagcgctta ctttcgtcat ttcagcgata cgttctacgg gcaaaccttc
    16441 gccccataaa atgaccggat ccccggcttt gtcctgcgcc tgtggaccta agtctacgca
    16501 gatcatatcc atcgccacgc gcccgacaat cggtacttcg cgaccgttca ccagcactgg
    16561 cgtaccggac ggcgcggcgc gcggataacc atcgccatag cccatcgcga ctacgccaag
    16621 acgggtatca cgttcgctta cccaggttcc accataacca acaggctctc cggctttatg
    16681 ctcacgcacg gcaatcaggc tggaggttag tgacatcact ggctgacagc caaaatcggc
    16741 accggtggag cgatcttcca gcggcgagac gccataaaga atgatgcccg ggcgcaccca
    16801 gtcaaaatgc gactgtggcc acagcagaat gccacccgac gcggcaatgg aacgttgacc
    16861 aggtttgcct tcgcaaaagg tattaaagat agcgagttgt ttctcggttg cgccacattt
    16921 tggttcatcc gcgcgcgcaa aatggctgac gatattcacc ggctgacgaa cgtttttgca
    16981 ctgggtcagg cgatgataaa acgcctcagc ctgttccggc cttacgccca gacggtgcat
    17041 accggtatcg agtttcatcc agacggtaac cggctcgtcc aggctagcct cttccagcgc
    17101 agccagctgt tcttcgttat gcacggcggt atgaaaatgt tgcgcagaaa tcgtcggcag
    17161 atctctggca tcaaaaaagc cttcgagtaa cagtacaggt ttggtgattc cccccgcacg
    17221 cagtcgcaga gcttcttcga gacgggctac gccaaaggcg tcagcatcgg ggagcgttcg
    17281 cgcggtctca agaagaccgt gaccataagc gttcgctttc accaccgcaa ccattttact
    17341 ggcaggggcc agttcacgaa gacgttgcag gttgtgtcgc agagcgcggc ggttaatcac
    17401 aacagttgcc gcttgcattt gtgttccttg ataagtgttt gctttaatta cctaattcat
    17461 aaaataatta ttattcgtcg tcgtactgcg gccccgcata gttgtcgaag cgcgaccatt
    17521 gaccgttaaa ggtcaggcgt accgtcccga ttgggccgtt acgttgttta ccgataataa
    17581 tttccgcgat gccttttaaa tcactgtttt cgtgatacac ctcatcacga tagataaaca
    17641 tgatcaagtc cgcatcctgc tcgatagagc cagattcacg caggtcggag ttgaccgggc
    17701 gtttgtcggc acgttgttcc agagaacggt tcaactggga cagcgccacc accggcacgt
    17761 tcagttcttt cgccagtgct ttcagcgagc gagagatttc tgcaatttcc agcgtacggt
    17821 tatcggaaag cgccggtacg cgcatcagtt gcaggtagtc gatcatgata agcccgatgc
    17881 cgccgtgttc acgggcaata cggcgtgcgc gggaacgcac ttccgttggc gtcaggccgg
    17941 aggagtcatc gatatagata ttgcgttttt cgagcaaaat acccatggtg ccggaaatgc
    18001 gcgcccagtc ttcgtcatcg agctgcccgg tacggatttt agtctggtca acgcgcgaca
    18061 gcgacgccag agaacgcatc atgatctgtt ctgatggcat ctccagcgag aagataagta
    18121 ccggtttatc ctgcaacatc gccgcgtttt cgacgaggtt catcgcaaat gttgttttac
    18181 ccatcgacgg acgcgcggcg acgatgatca aatccgacgg ctgcaagcca gcggtttttt
    18241 tgttgagatc gtcataaccg gtgtttaccc cggtaacgcc atcgtgtggc tgctgaaaca
    18301 actgctcaat acgcgccacg gttgcgtcga gcacatcggc gatgttcttc ggcccttcgt
    18361 ctttgttcgc acgactttcg gcaattttaa agacgcggga ttcagccaga tccagcagat
    18421 cttcgctggt acgcccctgc ggatcaaaac cagcttcggc aatctcattc gcaaccgaga
    18481 tcatctcacg gacaacggca cgttcacgca cgatgtccgc ataggcactg atgttagccg
    18541 cacttggcgt attttttgac agctctgcca gataagcaaa accaccgacg ctatcgagtt
    18601 gcccctggcg ttccagcgat tccgcaagag taatcagatc gatagggcta ccgctttcct
    18661 gcaaacgcgc catttcagta aagatatgac ggtgtgggcg ggtgtaaaaa tcgtctgcta
    18721 ccacacgctc ggctacatca tcccagcgtt cgttatctag cattaaaccg cccaacaccg
    18781 actgctccgc ttcgatcgag tgcggaggca ctttcagccc ggcaacttgt ggatcgcgtt
    18841 cgcggggttc agcctgctgt ttgttgaagg gtttatttcc tgccatagtg aatggagtta
    18901 ccgagataaa gaatgggtcg aaactttatc atatgaagca gaccctgacg atacgttctg
    18961 gaggacacat ggcaacacga attgaatttc acaagcacgg tggcccggaa gtacttcaag
    19021 ccgtagagtt cactcctgcc gatccggcgg agaatgaaat ccaggtcgaa aataaagcca
    19081 tcggcatcaa ttttatcgac acatatatcc gcagcggcct ttacccgccg ccatcgctac
    19141 ccagcggatt aggcaccgaa gcagcaggca tcgtgagtaa agtcggcagt ggtgtaaagc
    19201 atattaaggc aggcgatcgt gtagtctatg cgcagtcggc gttaggcgct tacagctctg
    19261 tgcataacat tattgcggat aaagcggcga ttctgcctgc ggcaatttct tttgagcaag
    19321 ctgcggcatc cttcctgaaa ggcttaacgg tttattatct gctgcgcaaa acctatgaaa
    19381 ttaaacccga tgaacagttc ctgttccacg cagcggctgg cggcgttggc ttaattgcct
    19441 gccagtgggc aaaagccctg ggcgcgaaac ttatcggcac cgtaggaacc gcgcaaaaag
    19501 cgcagagcgc gctaaaagcg ggcgcgtggc aggttattaa ctatcgtgaa gaggatctgg
    19561 tcgagcggtt aaaagagatc accggcggta agaaagtgcg cgtggtgtac gattccgtgg
    19621 gcagagacac ctgggaacgg tcgctggatt gcctgcaacg ccgcggctta atggtcagtt
    19681 ttggcaactc atcaggtgcg gttaccggtg tgaacttagg cattctcaat caaaaaggct
    19741 cgttgtatgt gacacgccct tccctgcaag gctatatcac cacgcgggag gaattaaccg
    19801 aggccagtaa tgaactgttc tctttgattg ccagcggtgt gattaaggtc gatgtcgccg
    19861 agcagcagaa atatccgctg aaggatgcgc agcgtgcgca tgagattctg gaaagccggg
    19921 cgacgcaagg ttccagcctg ctgattccat aaaagaaata gggcttccac ctgggaagcc
    19981 ctttcttttt atagttcggc tgtatgtagg gtacagcacg atgaatctgt tagaggcgca
    20041 atagtgacag atttgattat caattcctat tttgttctaa ggataaaacc ttaggttgtg
    20101 atcatccgca caatccctta gtaacgccag cggtcataac gctgatattt cggcactttt
    20161 ggtgctttaa tcgccttaat aacccacacc accgcaatcg ccagtagtaa ccacggcagc
    20221 aacttaatca tcaatgccag cataccgccg aggaacataa tggccgtcgc cacaaccagc
    20281 gcggcgataa tgcccagcaa cgaaacgccg gtgaccatca gcatgacaaa aaagccaatc
    20341 acaaaaagta gttccagcat gatgctctcc caaatatgaa atctcttgct ggcattacaa
    20401 gaatcatgcc aaaaataatc tattgattta acagcaaaac gccccgcgac ggtgcgcagg
    20461 gcgtggtgaa tttgactact ttttggtgaa aagttaacgc ttatccgcca ccagtttgag
    20521 cgcgtgttcc agcacattaa tgtctgcacc cgctttatgg gcattttcac ttaaataacg
    20581 ccgccactgc cgcgcgccag gaataccctg gaacaagccc aacatatgcc gggtaatatg
    20641 gccgagatac gtcccctggc tgagttcacg ctcaatgtac ggatacatgg cgcgcactac
    20701 cgccaccgga tcggcatcgg tatccgagga accaaagatc tcccggtcta ccgccgccag
    20761 aatacccgga ttctgatacg cctcgcgccc gaccatcacg ccatccatat gttgcaggtg
    20821 tgctttggcc tcttccagcg acttgatacc accgttaatc gacattgtca gatgcggaaa
    20881 gtcacgcttc agttgataca cacgcggata atcgagcggc gggatttcac ggttttcttt
    20941 cgggcttaac cccgaaagcc aggctttacg tgcgtggatg atgaacatct cacactcgcc
    21001 tttgccggaa acggtattga tgaaatcgca gagaaattca tagctgtcct ggtcgtcgat
    21061 gccaatacgc gttttcaccg tcaccggaat cgacaccaca tcgcgcatcg ctttcacgca
    21121 gtcggcaacc agctgcgcat tacccatcag acacgcacca aacatgccgt tctgcacccg
    21181 gtcagacggg cagccgacat tcaggttgat ctcatcatat ccgcgcgctt ctgccagctt
    21241 tgcacactgc gccagcgccg ccggatcgct accgcccagt tgcaacgcta ccggatgttc
    21301 ttcttcactg tacgccagat aatcaccttt accgtgaata atcgcccctg tggtcaccat
    21361 ttcggtatac agcaacgtat tgcgggaaag cagacgcaag aaatagcggc aatgtctgtc
    21421 cgtccagtcg agcattggtg caacgctaaa ccgaccactc cagtgaacgt cagttttttc
    21481 aggcattgcg ctggtttggt tgattttttg catttcagaa ttaccgtgca ttttcaaatg
    21541 tagagattat tttatcgata tatcatgggg ttatgttatt cagcatcact attcaggagg
    21601 ctcaatagcg gggtactata ccataacaac aggaagcgcc tgtctcattg caaaagaaaa
    21661 ttgagatcct ctcaaggcat gaagctctca cgaagtgatg gaaataatct tattagccgt
    21721 taactttgtt aaggccaatg ataaacaatc caggttcgac gataaataaa aaatcacaca
    21781 ttaaactctg gtgatatatc tccctgctaa tagcattgat agagaaaaaa gaacccaata
    21841 aatattgggt ccttttatat aatgccttcc atactatcga agaacttcac atattatttc
    21901 tccgatttaa ccccgaacaa atcataaatt aatttagaag tgtctgtaag tattttaatc
    21961 tcttcctttg aggttgggtc aaacgacttc gcgaagctaa ttaattgtgg tgcagcatct
    22021 cgcattttgc ttaaaatatc aggatcgagc gttccttcat tcaccagatg tgacatctta
    22081 tccagatagc catcaaaatt catttctccc ccatcagcca gacgcttcat ctctcccagg
    22141 tacttcttca tatcacgttg agataatttt tcaaactgag ctttcaggta gctctcatta
    22201 ttttcattaa tatacactgt ttctgataaa tctgcgtagg cactagaata tgaaagtgaa
    22261 attaacagcg aagcaaataa ttttaagctg ttgtcatcat gttcctggca ggcattaaca
    22321 aacgttaaaa aaccagaacc tattgcttga aaatgtatat tcgctaaagg ttcattatcc
    22381 ttagattcct cataaaatag ctgaaccgtg gagggaaggt cattcttagt ttctacatca
    22441 aaagtacatt gttcaatggg cattgcatct ttattatccc caggattaca tatactatta
    22501 atcgcgaaat gaaaaatagc ccggtcaaca actgatgcaa taaagtcacg atcgtttaaa
    22561 tcctcatcag tgcaatcgtc aatatactta ttgacccaca ttttgagatc atttatttgc
    22621 acaattaaaa acacattttt ttacgtgcat gccataaatt atgcgtgatt cgttgaataa
    22681 acaaatctat ttttgcaata attatatccc gatgacgcag cgctgcataa t
//
LOCUS       DAPOAV010000072        22641 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.072, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000072 DAPOAV010000000
VERSION     DAPOAV010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22641
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.072"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            316..1215
                     /gene="yegS"
                     /locus_tag="RN951_003182"
     CDS             316..1215
                     /gene="yegS"
                     /locus_tag="RN951_003182"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid kinase YegS"
                     /protein_id="HDX2528146.1"
                     /translation="MAEFPASLLILNGKSTDNLPLREAIMLLREEGMTIHVRVTWEKG
                     DAARYVEEARKLGVATVIAGGGDGTINEVSTALIQCEGDDIPALGILPLGTANDFATS
                     VGIPEALDKALKLAIAGDAIAIDMAQVNKQTCFINMATGGFGTRITTETPEKLKAALG
                     SVSYIIHGLMRMDTLQPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPNALIND
                     GLLQLRIFTGDEILPALVSTLKSDEDNPNIIEGASSWFDIQAPHDITFNLDGEPLSGQ
                     NFHIEILPAALRCRLPPDCPLLR"
     gene            complement(1297..2070)
                     /locus_tag="RN951_003183"
     CDS             complement(1297..2070)
                     /locus_tag="RN951_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDX2528147.1"
                     /translation="MNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLE
                     QKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQLSSAPKNRIAQAAVKMIHEGMTVI
                     LDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHGS
                     IAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNR
                     RGFNQVLPIEKIDIIITDDAVSEVDKLALQKTRVKLITV"
     gene            complement(2176..3216)
                     /gene="gatD"
                     /locus_tag="RN951_003184"
     CDS             complement(2176..3216)
                     /gene="gatD"
                     /locus_tag="RN951_003184"
                     /EC_number="1.1.1.251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDX2528148.1"
                     /translation="MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPR
                     IFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQ
                     CAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCE
                     NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAP
                     QMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKI
                     LRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIA
                     RNAMPGKVLLIP"
     gene            complement(3264..4619)
                     /locus_tag="RN951_003185"
     CDS             complement(3264..4619)
                     /locus_tag="RN951_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol permease IIC component"
                     /protein_id="HDX2528149.1"
                     /translation="MFSEVMRYILDLGPTVMLPIVIIIFSKILGMKAGDCFKAGLHIG
                     IGFVGIGLVIGLMLDSIGPAAKAMAENFDLNLHVVDVGWPGSSPMTWASQIALVAIPI
                     AILVNVAMLLTRMTRVVNVDIWNIWHMTFTGALLHLATGSWMIGMAGVVIHAAFVYKL
                     GDWFARDTRNFFELEGIAIPHGTSAYMGPIAVLVDAIIEKIPGVNRIKFSADDIQRKF
                     GPFGEPVTVGFVMGLIIGILAGYDVKGVLQLAVKTAAVMLLMPRVIKPIMDGLTPIAK
                     QARSRLQAKFGGQEFLIGLDPALLLGHTAVVSASLIFIPLTILIAVCVPGNQVLPFGD
                     LATIGFFVAMAVAVHRGNLFRTLISGVIIMSITLWIATQTIGLHTQLAANAGALKAGG
                     MVASMDQGGSPITWLLIQVFSPQNIPGFIIIGAIYLTGIFMTWRRARGFIKQEKVVLA
                     E"
     gene            complement(4623..4907)
                     /gene="gatB"
                     /locus_tag="RN951_003186"
     CDS             complement(4623..4907)
                     /gene="gatB"
                     /locus_tag="RN951_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIB"
                     /protein_id="HDX2528150.1"
                     /translation="MKRKIIVACGGAVATSTMAAEEIKELCQNHNIPVELIQCRVNEI
                     ETYMDGVHLICTTAKVDRSFGDIPLVHGMPFISGIGIEALQNKILTILQG"
     gene            complement(4938..5390)
                     /gene="gatA"
                     /locus_tag="RN951_003187"
     CDS             complement(4938..5390)
                     /gene="gatA"
                     /locus_tag="RN951_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIA"
                     /protein_id="HDX2528151.1"
                     /translation="MTNLFVRSGISFVDRSEVLTHIGNEMLAKGVVHDTWPQALIARE
                     AEFPTGIMLEQHAIAIPHCEAIHAKSSAIYLLRPTNKVHFQQADDDNDVAVSLVIALI
                     VENPQQQLKLLRCLFGKLQQPDIVETLITLPETQLKEYFTKYVLDSDE"
     gene            complement(5400..6662)
                     /gene="gatZ"
                     /locus_tag="RN951_003188"
     CDS             complement(5400..6662)
                     /gene="gatZ"
                     /locus_tag="RN951_003188"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatZ"
                     /protein_id="HDX2528152.1"
                     /translation="MKTLIARHKAGEHIGICSVCSAHPLVIEAALAFDRNSTRKVLIE
                     ATSNQVNQFGGYTGMTPADFREFVFTIADKVGFARERIILGGDHLGPNCWQQENADAA
                     MEKSVELVKEYVRAGFSKIHLDASMSCAGDPIPLAPETVVERAAVLCFAAESVATDCQ
                     REQLSYVIGTEVPVPGGEASAIQSVHITHVEDAANTLRTHQKAFIARGLTEALTRVIA
                     IVVQPGVEFDHSNIIHYQPQEAQPLAQWIENTRMVYEAHSTDYQTRTAYWELVRDHFA
                     ILKVGPALTFALREAIFALAQIEQELIAPENRSGCLAVIEEVMLDEPQYWKKYYRTGF
                     NDSLLDIRYSLSDRIRYYWPHSRIKNSVDTMMVNLEGVDIPLGMISQYLPKQFERIQS
                     GELSAIPHQLIMDKIYDVLRAYRYGCAE"
     gene            complement(6691..7545)
                     /gene="gatY"
                     /locus_tag="RN951_003189"
     CDS             complement(6691..7545)
                     /gene="gatY"
                     /locus_tag="RN951_003189"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416599.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HDX2528153.1"
                     /translation="MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAP
                     VIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVM
                     IDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADALYTNPAQA
                     REFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDI
                     QQTIKLGICKINVATELKNAFSQALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIA
                     DCGCEGRA"
     gene            complement(7853..8905)
                     /gene="fbaB"
                     /locus_tag="RN951_003190"
     CDS             complement(7853..8905)
                     /gene="fbaB"
                     /locus_tag="RN951_003190"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fructose-bisphosphate aldolase"
                     /protein_id="HDX2528154.1"
                     /translation="MTDIAQLLGKDADNLLQHRCMTIPSDQLYLPGHDYVDRVMIDNN
                     RPPAVLRNMQTLYNTGRLAGTGYLSILPVDQGVEHSAGASFAANPLYFDPKNIVELAI
                     EAGCNCVASTYGVLASVSRRYAHRIPFLVKLNHNETLSYPNTYDQTLYASVEQAFNMG
                     AVAVGATIYFGSEESRRQIEEISAAFERAHELGMVTVLWAYLRNSAFKKDGVDYHVSA
                     DLTGQANHLAATIGADIVKQKMAENNGGYKAINYGYTDDRVYSKLTSENPIDLVRYQL
                     ANCYMGRAGLINSGGAAGGETDLSDAVRTAVINKRAGGMGLILGRKAFKKSMADGVKL
                     INAVQDVYLDSKITIA"
     gene            9162..10439
                     /locus_tag="RN951_003191"
     CDS             9162..10439
                     /locus_tag="RN951_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2528155.1"
                     /translation="MKTTAKLSFMMFVEWFIWGAWFVPLWLWLSKSGFSAGEIGWSYA
                     CTAIAAILSPILVGSITDRFFSAQKVLAVLMFAGALLMYFAAQQTTFAGFFPLLLAYS
                     LTYMPTIALTNSIAFANVPDVERDFPRIRVMGTIGWIASGLACGFLPQILGYADISPT
                     NIPLLITAGSSALLGVFAFFLPDTPPKSTGKMDIKVMLGLDALILLRDKNFLVFFFCS
                     FLFAMPLAFYYIFANGYLTEVGMKNATGWMTLGQFSEIFFMLALPFFTKRFGIKKVLL
                     LGLVTAAIRYGFFIYGSADEYFTYALLFPGILLHGVSYDFYYVTAYIYVDKKAPVHMR
                     TAAQGLITLCCQGFGSLLGYRLGGVMMEKMFAYQEPVNGLTFNWSGMWTFGAVMIAII
                     AVLFMIFFRESDNEITAIKVDDRDIALTQGEVK"
     gene            10436..11440
                     /locus_tag="RN951_003192"
     CDS             10436..11440
                     /locus_tag="RN951_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HDX2528156.1"
                     /translation="MKTERILGALYGQALGDAMGMPSELWPRSRVKAHFGWIDRFLPG
                     PKENNAACYFNRAEFTDDTSMALCLADALLEREGKIDPNLIGRNILDWALRFDAFNKN
                     VLGPTSKIALNAIRDGKPIAELENNGVTNGAAMRVSPLGCLLPAHDVDSFIDDVALAS
                     SPTHKSDLAVAGAVVIAWAISRAIDGESWSAIVDSLPSIARHAQQKRITTFSASLAAR
                     LEIALKIVRNADGTESASEQLYQVVGAGTSTIESVPCAIALVELAQTDPNRCAVLCAN
                     LGGDTDTIGAMATAICGALHGVNAIDPALKAELDAVNQLDFNRYATALAKYRQQREAV
                     "
     gene            11437..12402
                     /locus_tag="RN951_003193"
     CDS             11437..12402
                     /locus_tag="RN951_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDX2528157.1"
                     /translation="MSGARLHTLLPELTSRQPVMVVGAAVIDVIADAYALPWRGCDIE
                     LKQQSVNVGGCALNIAVALKRLGIEAGNALPLGQGVWAEIIRNRMAKEGLISLIDNAE
                     GDNGWCLALVEPDGERTFMSFSGVENQWNRQWLARLTVAPGSLLYFSGYQLASPCGEL
                     LVEWLEKLQDVTPFIDFGPRIGDIPDALLARIMACRPLVSLNRQEAEIAAERFALSAE
                     ITTLGKQWQEKFAAPLIVRLDKEGAWYFSNDASGCIPAFPTQVVDTIGAGDSHAGGVL
                     AGLASGLPLADAVLLGNAVASWVVGHRGGDCAPTREELLLAHKNV"
     gene            complement(12376..13122)
                     /locus_tag="RN951_003194"
     CDS             complement(12376..13122)
                     /locus_tag="RN951_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDX2528158.1"
                     /translation="MEQAHTQLIAQLNERILAADNTPLYIKFAETVKNAVRSGVLEHG
                     NILPGERDLSQLTGVSRITVRKAMQALEEEGVVTRSRGYGTQINNIFEYSLKEARGFS
                     QQVVLRGKKPDTLWVNKRVVKCPEEVAQQLAVEAGSDVFLLKRIRYVDEEAVSIEESW
                     VPAHLIHDVDAIGISLYDYFRSQHIYPQRTRSRVSARMPDAEFQSHIQLDSKIPVLVI
                     KQVALDQQQRPIEYSISHCRSDLYVFVCEE"
     gene            complement(13174..13992)
                     /locus_tag="RN951_003195"
     CDS             complement(13174..13992)
                     /locus_tag="RN951_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416605.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HDX2528159.1"
                     /translation="MQLRITSRKKFTALLCVLGLISIIAIYPRQTVNFFYSTAVQIKD
                     YIHFYGYRPVKSFAIRIPASYTIHRIDVSRWQERIDWQRVAKMRDNGIRLQFAFIKAT
                     EGEKLVDPYFSRNWQLSRENGMLRGAYHYFSPSVSASVQARLFLQTVDFSQGDFPAVL
                     DVEERGKLSAKELRKRVSQWLKMVEKRTGKKPIIYSGAVFYHTNLAGYFNEYPWWVAH
                     YYQRRPDNDGMAWRFWQHSDRGQVDGINGPVDFNVFNGTVEELQGFVDGIKETP"
     gene            complement(14057..14857)
                     /gene="thiD"
                     /locus_tag="RN951_003196"
     CDS             complement(14057..14857)
                     /gene="thiD"
                     /locus_tag="RN951_003196"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDX2528160.1"
                     /translation="MKRINALTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAQ
                     NTRGVQSVYRIEPDFVAAQLDSVFSDVRIDTTKIGMLAETDIVEAVAERLQRYQIQNV
                     VLDTVMLAKSGDPLLSPSAVATLRSRLLPQVSLITPNLPEAAALLDAPHARNEQEMLE
                     QGRSLLAMGCGAVLMKGGHLDDEQSPDWLFTREGEQRFTAPRIMTKNTHGTGCTLSAA
                     LAALRPRHTNWADTVQEAKSWLSSALAQADTLEVGHGIGPVHHFHAWW"
     gene            complement(14854..15642)
                     /gene="thiM"
                     /locus_tag="RN951_003197"
     CDS             complement(14854..15642)
                     /gene="thiM"
                     /locus_tag="RN951_003197"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HDX2528161.1"
                     /translation="MQVDLLGSAQSAHALHLFHQHSPLVHCMTNDVVQTFTANTLLAL
                     GASPAMVIETEEASQFAAIASALLINVGTLTQPRAQAMRAAVEQAKSSQTPWTLDPVA
                     VGALDYRRHFCHELLSFKPAAIRGNASEIMALAGIANGGRGVDTTDAAANAIPAAQTL
                     ARETGAIVVVTGEVDYVTDGHRIIGIHGGDPLMTKVVGTGCALSAVVAACCALPGDML
                     ENVASACHWMKQAGERAVARSEGPGSFVPHFLDALWQLTQEVQA"
     regulatory      complement(15677..15773)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15865..16137)
                     /gene="rcnR"
                     /locus_tag="RN951_003198"
     CDS             complement(15865..16137)
                     /gene="rcnR"
                     /locus_tag="RN951_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II)-binding transcriptional repressor
                     RcnR"
                     /protein_id="HDX2528162.1"
                     /translation="MSHTIRDKQKLKARASKIQGQVVALKKMLDEPHECAAVLQQIAA
                     IRGAVNGLMREVIKGHLTEHIVHQGDELKREEDLDVVLKVLDSYIK"
     gene            16258..17082
                     /gene="rcnA"
                     /locus_tag="RN951_003199"
     CDS             16258..17082
                     /gene="rcnA"
                     /locus_tag="RN951_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel/cobalt efflux protein RcnA"
                     /protein_id="HDX2528163.1"
                     /translation="MTEFTTLLQQGNAWFFIPSAILLGALHGLEPGHSKTMMAAFIIA
                     IKGTIKQAVMLGLAATISHTAVVWLIAFGGMVISKRFTAQSAEPWLQLISAVIIISTA
                     FWMFWRTWRGERNWLENMHGHDYEHHHHDHEDHHDHGHHHHHEHGEYQDAHARAHAND
                     IKRRFDGREVTNWQILLFGLTGGLIPCPAAITVLLICIQLKALTLGATLVVSFSIGLA
                     LTLVTVGVGAAISVQQVAKRWSGFNTLAKRAPYFSSLLIGLVGVYMGVHGFMGIMR"
     gene            17301..17639
                     /gene="rcnB"
                     /locus_tag="RN951_003200"
     CDS             17301..17639
                     /gene="rcnB"
                     /locus_tag="RN951_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II) efflux transporter accessory
                     subunit RcnB"
                     /protein_id="HDX2528164.1"
                     /translation="MTIKNKMLLGVLLLVTSAAWAAPATAGSTNTSGISKYELSSFIA
                     DFKHFKPGDTVPEMYRTDEYNIKQWQLRNLPAPDAGTHWTYMGGAYVLISDTDGKIIK
                     AYDGEIFYHR"
     gene            complement(17721..18755)
                     /locus_tag="RN951_003201"
     CDS             complement(17721..18755)
                     /locus_tag="RN951_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative fimbrial-like adhesin protein"
                     /protein_id="HDX2528165.1"
                     /translation="MEIRIMLFILMMMVMPVSYAACYSELSVQHNLVVQGDFALTQTQ
                     MATYEHNFNDSSCVSTNTITPMSPSDIIVGLYNDTIKLNLHFEWTNKNNITLSNNQTS
                     FTNGYSVTVTPAASNAKVNVSAGGGGSVMINGVATLSSASSSTRGSAAVHFLLCLLGG
                     KSWDACVNSYRNALAQNAGVYSFNLTLSYNPITTTCKPDDLLITLEGIPVSQLPATGN
                     KATINSKKGDIILRCKNLLGQQNQTSRKMQVYLSSSDLLTNSNTILKGAEDNGVGFIL
                     ESNGSPVTLLNITDNSKGYTNLKEIAAKSKLTDTTVSIPITASYYVYDTNKVKSGALE
                     ATALINVKYD"
     gene            complement(18771..21251)
                     /locus_tag="RN951_003202"
     CDS             complement(18771..21251)
                     /locus_tag="RN951_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDX2528166.1"
                     /translation="MLRMTPLASAIVALLLGIEAYAAEETFDTHFMIGGMKDQQVANI
                     RLDDNQPLPGQYDIDIYVNKQWRGKYEIIVKDNPQETCLSREVIKRLGINSDNFASGK
                     QCLTFEQLVQGGSYTWDIGVFRLDFSVPQAWVEELESGYVPPENWERGINAFYTSYYL
                     SQYYSDYKASGNNKSTYVRFNSGLNLLGWQLHSDASFSKTNNNPGVWKSNTLYLERGF
                     AQLLGTLRVGDMYTSSDIFDSVRFRGVRLFRDMQMLPNSKQNFTPRVQGIAQSNALVT
                     IEQNGFVVYQKEVPPGPFAITDLQLAGGGADLDVSVKEADGSVTTYLVPYAAVPNMLQ
                     PGVSKYDFAAGRSHIEGASKQSEFVQVGYQYGFNNLLTLYGGSMVANNYYAFTLGTGW
                     NTRIGAISVDATKSHSKQDNGDVFDGQSYQIAYNKFVSQTSTRFGLAAWRYSSRDYRT
                     FNDHVWANNKDNYRRDENDVYDIADYYQNDFGRKNSFSANMSQSLPEGWGSVSLSTLW
                     RDYWGRSGSSKDYQLSYSNNWRRISYTLAASQAYDENHHEEKRFNIFISIPFDWGDDV
                     TTPRRQIYMSNSTTFDDQGFASNNTGLSGTVGSRDQFNYGVNLSYQHQGNETTAGANL
                     TWNAPVATVNGSYSQSSTYRQAGASVSGGIVAWSGGVNLANRLSETFAVMNAPGIKDA
                     YVNGQKYRTTNRNGVVVYDGMTPYRENHLMLDVSQSDSEAELRGNRKIAAPYRGAVVL
                     VNFDTDQRKPWFIKALRADGQPLMFGYEVNDIHGHNIGVVGQGSQLFIRTNEVPPSVN
                     VAIDKQQGLSCTITFGKEIDESRNYICQ"
     gene            complement(21267..21941)
                     /locus_tag="RN951_003203"
     CDS             complement(21267..21941)
                     /locus_tag="RN951_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HDX2528167.1"
                     /translation="MKGLLSLLIFSMVLPAHAGIVIYGTRIIYPAENKEVMVQLMNQG
                     NRSSLLQAWIDDGDTSLPPEKIQVPFMLTPPVAKIGANSGQQVKIKIMPNKLPTNKES
                     IFYLNVLDIPPNSPEQEGKNALKFAMQNRIKLFYRPAGIAPVNKATFKKLLVNRSGNG
                     LVIKNDSANWVTISDVKANNVKVNYETIMIAPLESQSVNVKSNNANNWHLTIIDDHGN
                     YISDKI"
     gene            complement(22021..22563)
                     /locus_tag="RN951_003204"
     CDS             complement(22021..22563)
                     /locus_tag="RN951_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX2528168.1"
                     /translation="MKRSIIAAAVFSSFFMSAGVFAADVDTGTLTIKGNIAESPCKFE
                     AGGDSVSINMPTVPTTVFEGKAKYSTYDDAVGVTSSMLKISCPKEVAGVKLSLITNDK
                     ITGNDKAIASSNDTVGYYLYLGDNSDVLDVSAPFNIESYKTAEGQYAIPFKAKYLKLT
                     DNSVQSGDVLSSLVMRVAQD"
BASE COUNT         5746 a         5738 c         5193 g         5964 t
ORIGIN      
        1 acaacatttc ctacataagt aggaattaca gactcagagg cccttccggg taaccctatg
       61 ggagctttaa tatatttgga atagtatatt gaagatgcca ctgtttagtt gaatattaga
      121 tatttgctct tttttcaaat ttaccggtgg ctaccgttaa cattcactgc ccccattgca
      181 agctcctggt ggtaacaact gaattaccca tgcttgaact gactttttat cctccgactt
      241 tcatcctgtt ctgactccac cttttgtttt ctgctctaca ctatctacag accaatcata
      301 aaggcacata cgatcatggc agaatttccc gccagcttac tgattcttaa tggcaaaagt
      361 actgacaatc tacccttgcg cgaagcaatt atgctgttgc gtgaggaagg aatgacgatc
      421 catgtgcggg tcacctggga gaaaggcgat gccgcacgat atgtagagga ggcccggaag
      481 ttgggcgtcg caacggtgat tgccggtggt ggcgatggca ccattaatga agtttctacg
      541 gcgttgattc agtgtgaggg ggatgacata cccgcgctgg gaattttgcc attaggaacc
      601 gccaatgatt ttgccaccag tgtagggatt cctgaggcac tggataaggc gctgaaactg
      661 gcaattgccg gtgacgccat tgcgatagat atggcgcagg tcaacaaaca aacctgtttt
      721 attaatatgg cgacaggcgg atttgggacg cgtattacca cagaaacgcc ggaaaaatta
      781 aaagccgcgc tgggtagcgt ctcttacatc attcatggct taatgcgtat ggatactctg
      841 caaccggacc gttgtgaaat ccgcggtgaa aactttcact ggcaaggtga cgccctggtc
      901 attggtattg gtaacgggcg tcaggccggt ggcggtcagc aattgtgtcc gaacgcgtta
      961 attaacgatg gcttgctgca actgcgcatt tttaccggcg atgaaatact tccggctctc
     1021 gtatcaacct taaaatctga cgaagataac ccgaatatta tcgaaggcgc ttcgtcgtgg
     1081 tttgatattc aggcaccaca cgacatcacc tttaatcttg atggcgaacc gttgagtggg
     1141 caaaattttc atattgaaat acttccggca gcgttgcgtt gtcgattacc accagattgt
     1201 ccactgttgc gttaatcaaa ctattctctc ttgaaccagg gagaatccgt aatgccggat
     1261 gcggtgtaaa caccttatcc ggcatacaga acaatactac accgtaatta attttacccg
     1321 cgtcttctgc aatgccagtt tatccacctc tgacacagca tcatcggtaa taataatgtc
     1381 aattttttcg attggtagta cctgattaaa accgcgacgg ttaaatttcg atgaatcgag
     1441 aacggcaatc actttattag cggctgtgac catcgcaccg ctaatagaat aaccttcatt
     1501 aaaggtcgta ataccattaa ccgcatcaat accatcagca ccgacaaaca ttaaatcggc
     1561 attaatatcc tgtaatgaac gctcggcaat ggaaccatgc atcgagcgcg ttttatggcg
     1621 gaccgtgcca ccacagacga ccagagtaat gtctttattt tcggaaaggg caaacgctgc
     1681 cgggagactg ttggtaatca ccgtgatatt tttggcggtc attaatcctt cggcgataag
     1741 cattgtcgta cttccgctgt cgagaataac ggtcatccct tcgtggatca ttttgactgc
     1801 cgcctgcgct attctgtttt ttggcgcgct ggagagctga aatcgctctt taaacccgac
     1861 ttcctgggtc tcggtttcac tattaccaga cattattttc gccgcaccgc catgaaagcg
     1921 cgtaaccacg cctttttgtt cgagaaagcg caaatcggca cggattgtcg cttccgaggc
     1981 agcaaatact cccgccagat cctgaacaag cacggttccc tgttcattca ctaattggat
     2041 gatcttattc cttcgctcga atgaattcat cgtcatttac ccatattcaa ttgtggctag
     2101 tgtaaacgaa gggggaccat tggtgaatga tctgttttgc acaataccgg gccagcatca
     2161 cgctggcccg cggtttcagg gaatgagcaa cactttgccc ggcatagcat tacgagcgat
     2221 gtcacgcacc gcctgggcga agctttcaaa gcttccacgg tgagcgatta atggctccag
     2281 gcttaactta cgttctgtca gcaaccggct cgccgtttcc cactcctgcc ccggccaagg
     2341 gctggagtag ttcatccaac tgccgataac cgtcagctct ttacgcaata ttttgccaaa
     2401 cgttgccgat gttaaatgca gatcctgatg caacgtgccc accagcgcca gttgggcatg
     2461 aggaccggca atctctaccg ccagttcgac agtttgcggt acgccagccg tctcgaggat
     2521 aagctgatta aagcgcagtt cgcgtaaaac gctctgcatt tgcggcgcgc tcatttcgct
     2581 actgttaaat gtttgcatcg caccgaaaga ttttgccagt gccagttttt ctgaactaat
     2641 gtcgatcgcc gtcacactct ttgctcccag cgcgacagcg cactgaatgg ccagcaggcc
     2701 aatggttccg gcaccaataa taataacgtt tttattctca caaccttgcg ctaaatgaaa
     2761 agcatgcaga ccaacggtaa tcggctcaat aaaagcccca tcctcaatag gcatatccgt
     2821 gggtagagca aagacatttt ttcgcttaac gacaatatat tcagcaaatc caccatcacg
     2881 ccgcgagcca ataaaatcat attttgcgca ctgggaataa aaccctttca gacactctgg
     2941 acaagtaaaa cagggtaata acggcacaca ggcaaccgca tcgccagggt gtaaatcatc
     3001 aacaccggat cccaccgcat caatatagcc gctaaattca tggcctaacg ttattggata
     3061 ataatgtgca ccatttttaa atatcctggg taaatcggaa ccacataagc ccgagctggc
     3121 aatttttacc cgcacctcat cctgatgttt aatttcagga atgacgcttt ctgcaacgcg
     3181 cacgatacca tcagtatcat tcaccactga tttcataaaa actcctgatt gttaaggggg
     3241 ataacctccc cctcaggtaa aaattattct gcgagaacga ctttctcttg tttaataaag
     3301 ccacgcgctc tacgccaggt catgaaaata ccggtcagat aaattgcacc gataataatg
     3361 aaaccgggaa tattttgcgg ggagaaaacc tgaatcagta accaggtaat gggagaaccg
     3421 ccctgatcca ttgaagccac catacccccg gcttttaacg ccccagcatt agccgccagt
     3481 tgggtgtgca aaccaatagt ttgcgtcgcg atccacaggg tgatgctcat aatgatgaca
     3541 cccgagatta aggtgcggaa cagatttcca cgatgcacgg cgaccgccat cgccacgaag
     3601 aagccgatgg tggcaagatc gccaaacggc agcacctgat tacccggcac acaaacagca
     3661 attaaaatgg tgagtgggat aaaaatcagg cttgccgata ccaccgccgt atgtcccagc
     3721 agcaacgccg gatcaaggcc aatcaggaac tcctgaccgc cgaacttcgc ctgtaaacga
     3781 ctacgagcct gcttagcgat gggcgttaaa ccatccatga tgggtttaat cacccgtggc
     3841 attagcagca tcactgccgc cgtttttacc gccagctgca atacaccttt gacatcgtaa
     3901 cccgcgagga tgccgataat cagccccatc acaaaaccca cggtgacagg ctcgccaaat
     3961 ggaccaaatt tgcgctgaat atcgtcggcg ctaaatttaa ttcggttaac gcctgggatt
     4021 ttctcgatga tagcatcgac cagcaccgca atcggcccca tatacgccga cgtaccgtgc
     4081 ggaatagcaa taccttccag ctcaaagaaa tttcgggtat cgcgggcaaa ccagtcgccg
     4141 agcttataaa caaacgccgc gtgaattacc acacctgcca tccctatcat ccatgaaccg
     4201 gttgccagat gcagcaacgc gccggtgaag gtcatatgcc agatattcca gatatcaaca
     4261 tttaccaccc gcgtcatacg ggtcagtaac atggccacgt taaccagaat cgcaatcgga
     4321 atcgccacca gcgcaatttg cgacgcccag gtcattggtg aagagcccgg ccagccaaca
     4381 tcgaccacat gcagattcag gtcgaaattt tccgccatcg ctttcgccgc cgggccaatg
     4441 gaatccagca ttaagccaat cacaaggcca atgccaacaa agccaatccc gatatgcaga
     4501 cccgctttaa agcaatcgcc tgccttcatg cctaatattt tagaaaaaat aatgatgaca
     4561 atcggcagca tcaccgtagg gccgaggtcg agaatataac gcatgacttc tgaaaacata
     4621 ggtcacccct gtaagatagt cagaatttta ttttgtaatg cttcgatacc gataccagaa
     4681 ataaaaggca tgccgtgaac taacggaata tcgccaaaac tacgatccac tttggcagtg
     4741 gtgcatatca aatgcacacc atccatatag gtttctattt cattaacccg acactggatt
     4801 aattcaacag gaatattatg attctgacac aactctttaa tttcttccgc cgccatcgta
     4861 gaggtcgcaa ccgcgcctcc gcaagcgaca ataatcttgc gtttcataaa tagtcctttt
     4921 tattgttaca gagggattta ttcgtctgaa tctaaaacat actttgtgaa gtattccttt
     4981 aactgggttt caggaagagt gattagtgtc tcgacgatat cgggctgttg taacttgcca
     5041 aataaacagc gtaaaagttt caattgctgc tgcggatttt ccacaatcaa cgcaataacc
     5101 aacgataccg ccacgtcgtt atcatcatcc gcttgctgaa aatgaacttt atttgttggc
     5161 cttaacagat aaatggctga cgacttagca tgaatcgcct cacaatgcgg tattgcaata
     5221 gcgtgctgct caagcattat cccggtaggg aattctgctt ctctggcaat taatgcctgt
     5281 ggccaggtat catgaaccac acctttggcg agcatctcat taccgatatg ggttaaaact
     5341 tcgctacgat cgacaaaaga aattccgcta cgaacaaaca ggttagtcat ataccgtcct
     5401 tattccgcac agccgtagcg ataggcgcgc aaaacatcat aaattttatc cataatcagc
     5461 tgatgcggta ttgctgataa ttccccggac tgaatgcgtt caaattgttt gggaagatac
     5521 tgactaatca tgcccagtgg gatgtccacg ccttcaagat tcaccatcat cgtatcgacg
     5581 ctatttttaa tccgactatg cggccagtaa taacgaatac gatccgacag gctgtaacga
     5641 atatccagta atgaatcgtt aaaacccgta cgataatatt ttttccagta ttgcggttcg
     5701 tcgagcatca cttcttcaat taccgccagg caaccgctgc gattttcagg ggcgataagt
     5761 tcctgctcaa tttgtgccag tgcaaatatc gcctcgcgta aagcaaaggt taatgcggga
     5821 ccgactttca atattgcaaa gtgatcgcgg actaattccc aataagccgt ccgggtctgg
     5881 taatcggtag aatgtgcttc ataaaccatt cgggtgtttt ctatccattg cgccagcggc
     5941 tgcgcttcct gcggctgata atggataata ttgctgtgat caaattccac acccggctgc
     6001 accacgatgg caatcacacg tgttaacgcc tctgtcagcc cacgggcaat aaaggccttt
     6061 tgatgcgtac gtaaagtatt ggcggcatct tcaacatggg tgatgtgtac tgactgaatg
     6121 gcgctggcct caccgcccgg aaccggaact tcggtgccaa tgacatagct cagttgctca
     6181 cgctggcaat ctgtcgccac actttccgca gcaaagcaaa gcacagcagc tcgttccaca
     6241 accgtttctg gtgctaacgg tatgggatcc cccgcgcagg acattgacgc atcaagatga
     6301 attttactga agccggcacg aacatattcc tttaccagct cgacggattt ttccatcgcc
     6361 gcatccgcat tttcttgctg ccagcagttt ggccccagat gatcgccgcc gagaataatg
     6421 cgttcgcgtg caaacccaac tttatcggca atcgtaaaaa caaattcgcg aaagtctgcc
     6481 ggtgtcattc cggtataacc gccaaattga ttgacctggt ttgacgttgc ttcaatcagc
     6541 actttgcgcg tgctgttgcg atcaaatgcc agcgccgctt cgataaccaa cggatgggca
     6601 gaacagactg aacatatgcc gatatgttca ccagctttat gccgggcaat taacgttttc
     6661 atgttttttc cttgttaaat ggcaggtgcg ttatgccctg ccctcgcagc cacaatcggc
     6721 aatcactttg ctcaccacat cgcgcattgc ggatttagcc gactgcaaat aatcccgggg
     6781 atcggtcgct tcagggtgct cggtcaggta attttttaac gcctgcgaga aggcattttt
     6841 cagctccgtt gcaacgttga ttttgcatat ccccagtttg atggtttgct gaatatcctt
     6901 agtcgataac cctgacgcgc catgcagcac cagcggtaag ttcacccact ggcgaatgtt
     6961 ctccagtcta gaaaaatcaa gcgccggtgc gctggcatac atcccatgag ccgtgccgat
     7021 ggcgaccgcc agggaatcaa ttccggttgc ctcggcaaat tcacgcgcct gagcggggtt
     7081 ggtgtacaac gcatcggctt cattgacttg cacatcatct tcctggccgc caagttgccc
     7141 cagctccgcc tcgacgctga catcaaagcg atggcaaaaa tccaccacct ctttgacccg
     7201 tgaaatattt tgcgcaaaag gcaaatgcga ggcgtcaatc atgactgagc gcacgccaga
     7261 acgaaccttc tgagcgatat cgtcaaattt cgtgtgatgg tcgagatgaa ttgccagtgg
     7321 atggtgatat tgcttcgcca tcgcgctgac cagcgccaac agattttctg taccagcatg
     7381 agtaaatgtg ccaggcgttc cggcgatgat gaccggcgca tgcaggttgg cagcggtttc
     7441 taccaccact tgcatcgttt cgagattgtg aatattgaat gccggaaccg cataaccgcc
     7501 gcgctgtgcg ttgttcagca tctgctttgt cgataccacg tacattttca tatcctgtcg
     7561 tttgttttcg atttcaaaat ataatgaaat tatttgtttt taaatatcga gataacgatc
     7621 acaaaaacga caatatgaaa attgttcgag gagtgaaagg caaaaaaacg gcctcccgat
     7681 agggaagccg tagcaaagtg cgcgtgtttt tatgccggat gcggtgtaaa catacgtggc
     7741 agtgctatgt aggcatgata agacgcttca gcgtcgcatc aggcataggt tgccggatgc
     7801 agcgtaaacg ccttatccgt cctacggggt ggtgttgttc gtataaggcg tatcaggcga
     7861 tagtaatttt gctatcgaga taaacgtcct gcacggcgtt aatcagtttc acgccgtcag
     7921 ccatcgattt cttgaacgct ttacgtccaa gaatcagccc cattccgcca gcgcgtttgt
     7981 tgataaccgc agtacgcact gcatcactga ggtcagtttc accgcccgca gcaccgccgg
     8041 agtttatcaa cccagcccgg cccatatagc agttagctaa ctgataacgc accagatcaa
     8101 tcgggttttc gctggttaac ttgctgtaca cgcgatcgtc ggtataaccg taattaatcg
     8161 ctttataacc gccgttattt tccgccattt tctgtttgac gatgtccgcg ccaatggtcg
     8221 ccgccagatg gttcgcctga ccagtcaggt cggcggaaac atggtaatca acgccatctt
     8281 tcttaaaggc ggagttacgc aaataggccc acagcactgt caccatgccc agctcgtgcg
     8341 cacgttcaaa agccgcagaa atttcttcaa tctggcgacg tgactcttcc gagccaaaat
     8401 agatagtcgc accaaccgca accgcgccca tgttgaacgc ctgctccacg ctggcataca
     8461 gcgtttgatc gtaggtattc gggtaactta gcgtctcgtt gtgattaagt ttgacgagga
     8521 atggaatgcg atgcgcataa cgccgcgata ccgacgccag cacgccgtaa gttgacgcca
     8581 cacagttaca gcccgcttcg atcgccagtt caacaatgtt tttcgggtca aagtagagcg
     8641 ggttagcagc aaatgaagct ccggcagagt gctcaacgcc ctggtcaacc ggcagaatag
     8701 aaagatatcc tgtgccagcc agacgcccgg tgttgtacaa cgtctgcata ttacgtaaca
     8761 ccgcaggcgg gcgattattg tcaatcatca cgcggtctac gtagtcatgt ccggggagat
     8821 aaagctggtc agaaggaata gtcatacaac ggtgctgtaa aaggttgtcg gcgtctttgc
     8881 caagcaactg cgcaatatct gtcattacta tgctcccgta aattccgatt ggatatcggc
     8941 tatggatttt cctggcccgc cttttgcggg caatcataat cctggtcgtt acgggcgagt
     9001 ttttccatct tttggatgtt ttttcagcgt tttctgttgg ctcgattcat cagaaaaaat
     9061 gttagcgcgg tcaagttttc accgcaaagg tatttaaaag gtattattaa gtggtattgt
     9121 catcgcgtac cttacattac ctgtcatgaa ggaattaaaa gatgaaaaca acagcaaagc
     9181 tgtcgttcat gatgtttgtt gaatggttta tctggggcgc gtggtttgtg ccattgtggt
     9241 tgtggttaag taaaagcggt tttagtgccg gagaaattgg ctggtcgtat gcctgtaccg
     9301 ccattgcggc gatcctgtcg ccaattctgg ttggctccat cactgaccgc tttttctcgg
     9361 cgcagaaagt gctggcggta ttgatgttcg caggcgcgct gctgatgtat ttcgctgcgc
     9421 aacagaccac ttttgccggg ttcttcccgt tactgctggc ctactcgcta acctatatgc
     9481 cgaccattgc gctgactaac agcatcgctt ttgccaacgt gccggatgtt gagcgtgatt
     9541 tcccgcgcat tcgtgtgatg ggcactatcg gctggattgc ctccggtctg gcatgtggtt
     9601 tcttgccgca aatactgggg tatgccgata tctcaccgac taacatcccg ctgctgatta
     9661 ccgccggaag ttctgctctg ctcggtgtgt ttgcgttttt cctgcccgac acgccaccaa
     9721 aaagcaccgg caaaatggat attaaagtca tgctcggcct ggatgcgctg atcctgctgc
     9781 gcgataaaaa cttcctcgtc tttttcttct gttcattcct gtttgcgatg ccactagcgt
     9841 tctattacat ctttgccaac ggttatctga ccgaagttgg catgaaaaac gccaccggct
     9901 ggatgacgct cggccagttc tctgaaatct tctttatgct ggcattgccg tttttcacta
     9961 aacgctttgg tatcaaaaag gtattattgc ttggtctggt caccgctgcg atccgctatg
    10021 gcttctttat ttacggtagt gcggatgaat atttcaccta cgcgttactg ttccccggta
    10081 ttttgcttca cggcgtaagt tacgattttt actacgttac cgcttacatc tatgtcgata
    10141 aaaaagcccc cgtgcatatg cgtaccgctg cgcaggggct gatcacgctc tgctgccagg
    10201 gcttcggcag tttgctcggc tatcgtcttg gcggtgtgat gatggaaaag atgttcgctt
    10261 atcaggaacc ggtaaacgga ctgactttca actggtccgg gatgtggact ttcggcgcgg
    10321 tgatgattgc cattatcgcc gtgctgttca tgattttttt ccgcgaatcc gacaacgaaa
    10381 ttacggctat caaggtcgat gatcgcgata ttgcgttgac acaaggggaa gttaaatgaa
    10441 aacagaacgt attctcggtg ctctttatgg gcaggcgtta ggggatgcga tggggatgcc
    10501 ctccgagctt tggccacgca gccgcgttaa agcacacttt ggctggattg accgttttct
    10561 tcctggacca aaggagaata acgcggcctg ttattttaac cgcgccgaat tcaccgacga
    10621 tacctcgatg gcgctgtgtc tggcggatgc gttactggaa cgtgaaggca agatcgatcc
    10681 gaatctgatt gggcgtaata ttctcgactg ggcgctgcgt ttcgacgcct ttaacaaaaa
    10741 cgtacttggt ccgacctcga agattgcgct taacgccatt cgcgacggta aacccattgc
    10801 tgaactggaa aacaacggcg tgaccaacgg cgcagcgatg cgcgtctcgc cattaggttg
    10861 tttgcttccg gcgcacgatg ttgattcctt tattgatgat gtggcgctgg cgtccagccc
    10921 gacccataaa tccgatctgg cggttgcagg cgcggtagtc atcgcatggg cgatttctcg
    10981 tgccattgac ggagaaagct ggtcagcgat tgtagattca ctgccttcaa ttgcgcgaca
    11041 tgcacagcaa aaacgcatca ctaccttcag cgcctcactg gcagcacgtc tggagattgc
    11101 gctgaaaatt gtgcgcaatg ccgacggcac cgaatccgcc agcgaacagc tttaccaggt
    11161 cgttggcgca ggtaccagca ctattgagtc cgttccgtgc gccattgcgc tggttgaact
    11221 ggcacaaacc gacccgaatc gctgcgccgt cctgtgcgct aaccttggcg gcgacacaga
    11281 caccatcggc gctatggcga cggcgatttg cggcgcgttg catggcgtta acgctatcga
    11341 tcctgcatta aaggcggaac tggatgcggt aaatcagctt gatttcaacc gctatgccac
    11401 agcgctggcg aaatatcgtc aacaacggga ggcggtatga gcggcgctcg attacacacg
    11461 ctgctgcctg aattaacctc gcgtcagccg gtgatggtcg tcggcgcggc ggtcattgat
    11521 gtgatcgccg acgcttatgc cctcccctgg cgtgggtgcg atatcgaact gaagcagcag
    11581 agcgttaacg ttggcggctg cgcactgaat attgccgtgg cgttaaagcg cctcggcatc
    11641 gaagcgggta atgccttgcc gctcggtcag ggcgtgtggg cggagattat tcgcaaccgg
    11701 atggcgaaag aggggttaat cagcctgatc gataacgccg aaggcgataa cggctggtgt
    11761 ctggcgctgg ttgagccgga tggcgaacgc acttttatgt cattcagcgg tgtggaaaat
    11821 cagtggaatc gccagtggct ggcgcgatta accgttgcgc ctggcagcct gctctatttt
    11881 tccggttatc aactggcctc gccctgcggc gaattgttag tggaatggct ggaaaagctg
    11941 caagacgtga cgccgtttat cgattttggc ccacgtatcg gcgatatccc ggacgcatta
    12001 ctggcgcgga tcatggcctg tcgaccttta gtatcactca atcgtcaaga ggctgagatt
    12061 gccgccgaac gttttgcttt atccgcagag ataacaacac ttggcaagca atggcaggag
    12121 aaatttgccg cgccgttgat cgttcgtctc gataaagagg gtgcatggta tttcagcaac
    12181 gacgcttctg gctgcattcc ggcatttcca acgcaagttg tagacaccat tggggcgggc
    12241 gacagtcatg caggtggcgt acttgccggg ctggcctctg gtctgccact ggcggatgcc
    12301 gtattactgg gcaatgcagt ggcgtcgtgg gttgtcgggc atcggggcgg tgattgtgcg
    12361 ccaacgcgcg aggaactact cctcgcacac aaaaacgtat agatcgctgc gacagtggct
    12421 aatgctgtac tcaataggcc gttgctgttg gtcaagcgcc acttgcttga tcaccagcac
    12481 cggtattttg ctatctaact gaatatgtga ctgaaactcg gcatccggca tccgggcgct
    12541 aacgcgggaa cgtgtacgtt gtgggtaaat gtgctggctg cggaaatagt cataaagtga
    12601 aatcccgatg gcatcaacat catgaattaa atgcgccgga acccacgatt cctcaatcga
    12661 taccgcttct tcatcgacat agcgaatacg cttaagcaaa aagacatcac ttcctgcttc
    12721 gaccgccagc tgctgcgcga cttcttcggg acatttcacg acacgcttgt taacccatag
    12781 cgtatcgggc tttttcccgc gcaataccac ctgctgagaa aaacctcgcg cttctttcaa
    12841 cgagtattcg aagatgttgt tgatctgcgt gccgtaaccg cgcgaacgcg tcaccacacc
    12901 ctcttcttcc agcgcctgca tcgccttgcg caccgtaatg cgcgaaacgc cggttaactg
    12961 acttaaatca cgctcaccgg gcaaaatatt gccatgctcc agcaccccgc tgcgcacggc
    13021 attttttacc gtttcggcaa acttaatata aagcggcgtg ttatccgcag ctaaaatacg
    13081 ctcgttcagt tgggcaatca gctgggtatg cgcttgttcc atttgtcttt ttcctgccag
    13141 ggagtctggt gggagtatat cactgcttct tatttaaggc gtttctttaa tcccatcaac
    13201 gaatccctgc aactcctcca ccgtgccatt aaacacatta aaatccaccg gaccattgat
    13261 gccatctacc tgtccacggt cggaatgctg ccagaagcgc caggccattc cgtcattgtc
    13321 cggacgacgt tgataatagt gagccaccca ccacggatat tcattaaaat agcccgccag
    13381 attcgtgtga taaaaaacgg ctcctgagta aataatcggc ttttttcccg tgcgtttttc
    13441 taccattttt agccactgac ttacccgctt gcgtaattct tttgccgata attttccccg
    13501 ttcttctacg tccagcacgg cagggaaatc gccttgtgag aaatccaccg tttgcagaaa
    13561 taatcgcgcc tgaactgaag cggataccga cggggagaaa taatgatacg ccccacgcag
    13621 catgccattt tcgcggctta gttgccagtt acgcgaaaaa taggggtcca ccagcttttc
    13681 gccttccgtc gccttaataa aagcaaactg taagcggata ccgttgtcgc gcatttttgc
    13741 cacccgctgc cagtcgatcc gctcctgcca gcgcgaaaca tctattctgt gaatggtata
    13801 actggcagga atgcgaattg cgaaagattt aaccgggcga taaccgtaga agtggatgta
    13861 gtctttaatc tgaactgctg tcgaatagaa aaaattcacc gtctgacgcg gataaattgc
    13921 aatgatggaa attagcccaa gaacgcataa taaagcggtg aatttttttc gactggtgat
    13981 tctcagctgc attggtttca tccctgaatg tcagtgccaa agactgacaa taaccaaagc
    14041 agctatagta cggtgctcac caccaggcgt ggaagtggtg aaccggacca ataccgtgac
    14101 caacttccag cgtgtcggcc tgggctaacg ccgatgaaag ccagcttttt gcctcctgta
    14161 cggtgtcagc ccagtttgta tggcgcgggc gtagtgcagc caacgccgca gagagtgtac
    14221 aaccagtgcc gtgggtgttt ttggtcataa tgcgcggtgc ggtaaaccgt tgttcaccct
    14281 cgcgagtaaa cagccagtcc gggctttgct catcatccag atgaccacct ttcattagca
    14341 ctgcgccaca gcccatcgcc aacagcgatc gcccttgttc cagcatttcc tgttcgttgc
    14401 gcgcgtgtgg cgcgtcgagc aaggcggcag cttcgggcaa gtttggcgtt attaatgaaa
    14461 cctgtggcaa taatcgactg cgcagcgtag caaccgccga aggtgaaagc agcggatcgc
    14521 cgctttttgc cagcataaca gtgtcgagta ccacgttttg gatctgataa cgttgcaacc
    14581 gttctgccac cgcttcaaca atatcggttt ccgccaacat accgatttta gtggtatcga
    14641 ttcgcacatc gctgaacacc gaatcgagct gggcggcgac aaaatcaggc tcaatgcgat
    14701 acaccgactg tacgccacgg gtattttgcg ccaccagtgc agtaataact gagcaaccat
    14761 aagcgccaag tgccgagaag gttttaagat cggcctgaat ccccgcacca ccactcggat
    14821 cagtaccggc aatcgtcaga gcgttaattc gtttcatgcc tgcacctcct gcgtcaattg
    14881 ccagagcgca tcaaggaaat gtggaacaaa actgcctggc ccctcgcttc tggcgacagc
    14941 gcgttctccg gcttgtttca tccagtgaca ggcagatgcg acattttcca gcatatcgcc
    15001 tggtaaggca caacaggcag cgacaaccgc cgataatgca cagccagttc ctaccacttt
    15061 ggtcattaac ggatcgccac cgtgaatacc aatgatacga tgtccatcgg taacataatc
    15121 cacctcgcca gtgaccacga cgattgcgcc agtttcccgt gccagtgttt gtgcagcggg
    15181 tatcgcgtta gctgcggcgt cagtggtatc cactccccgt ccgccattag caatgccagc
    15241 taatgccatg atttccgaag cattaccacg tatcgctgcc ggtttaaaag ataaaagttc
    15301 atgacaaaaa tggcggcgat aatcgagcgc acccaccgct actggatcaa gcgtccaggg
    15361 tgtttgagag ctttttgctt gctcaacggc agcacgcatc gcctgtgcgc gtggctgcgt
    15421 cagtgtgcca acgttaatca acaaggcact ggcgatagcc gcaaactgac tggcctcttc
    15481 ggtttcgata accatcgctg gcgatgcacc gagcgccagc aaggtattgg cggtaaaggt
    15541 ttgcaccaca tcattggtca tgcagtgcac aagaggggaa tgttggtgaa aaaggtgtaa
    15601 cgcgtgcgca gattgcgctg aacccagcag gtcgacttgc atagtttgct cctgccataa
    15661 cgtgaagaag caatgacctg gtggtccgtg acttccctac gctggcatta tccagatcag
    15721 gtgatacggg tatttctcag ccttcacgca gaagggcacc ccgagtcgtt tggttgcgat
    15781 gataaatcgc agaggaggat ggtaatgtcc agcgcacgcg ttgtaaacga ggaaaaacgg
    15841 cagttttaca atcgcgttaa taaattattt gatatatgaa tccagcacct tcagaacgac
    15901 atccagatct tcttcacgtt ttagctcatc cccctggtga acgatgtgtt ccgtcagatg
    15961 acctttaatc acttcccgca tcagaccgtt taccgcgcca cggatagcag caatctgttg
    16021 taaaactgca gcgcattcgt gcggctcgtc gagcattttc ttgagcgcca cgacctggcc
    16081 ctgaatctta ctggcacgcg ctttcagttt ctgtttatca cggattgtat gagacatggc
    16141 aacacctggt taacaagaat atgaaaaatc atagcactat taatctactg gggggtagta
    16201 tcaggtactg ggggggagta gaatcagatt gccgaattaa tactaagaat tattatcatg
    16261 accgaattta caactcttct tcagcaagga aacgcctggt tcttcatccc cagcgccatc
    16321 ttacttggtg cgcttcatgg cctggaacca gggcactcaa aaacgatgat ggcggcgttt
    16381 atcatcgcca tcaaaggcac cattaaacag gcggtgatgc tcggactggc agcaaccatt
    16441 tcgcataccg cggtggtctg gttgattgcc tttggcggga tggtgatcag taagcgcttt
    16501 actgctcaat cagcagaacc gtggctccag ctgatttccg cagtgatcat tattagcacc
    16561 gcgttctgga tgttctggcg tacctggcgc ggcgaacgca actggctgga gaatatgcac
    16621 gggcatgatt atgagcatca tcatcacgat cacgaagatc accacgacca tggacatcat
    16681 caccatcacg aacatggcga gtatcaggat gcccatgcac gagcccatgc caatgatatt
    16741 aaacgacgct ttgatggtag agaggtcacc aactggcaaa ttttgttatt tggcttaaca
    16801 ggtggtctta tcccctgtcc ggcagcaatt accgtgctgt tgatttgcat tcagttgaaa
    16861 gccctgacac tgggcgcaac actggtcgtc agtttcagca ttggcctggc gttaacgctg
    16921 gtcaccgtag gcgttggcgc agcaatcagc gttcagcagg tcgcaaaacg ctggagcgga
    16981 tttaacactc tcgctaaacg cgccccctat ttttccagtc tgttgattgg cttagttggt
    17041 gtgtatatgg gcgtacatgg cttcatgggc ataatgcgat aactcaatcc tttaggcttg
    17101 catgttatct tcagcccagg atgattctta aatcagctat ttccgctgac tctctgctcg
    17161 ctaaggatgc ttttagggca tcctttcatt tacacttttt acgaaatcat gggatcacta
    17221 acaaaatatc gcttgtcagt tatattgtat ggcaggaaag atatgcgact gatattacag
    17281 atccccaaag tggagagttt atgaccatta aaaataagat gttgctgggt gtgcttttgc
    17341 tggttaccag tgccgcctgg gccgcaccag ccaccgcggg ttcgaccaat acctcgggaa
    17401 tttctaagta tgagttaagt agtttcattg ctgactttaa gcatttcaaa ccaggtgata
    17461 ccgtcccaga gatgtaccgc accgatgagt acaacattaa gcagtggcag ttacgtaacc
    17521 tgcccgcgcc tgatgccggg acgcactgga cctatatggg tggcgcgtac gtgttgatca
    17581 gcgacaccga cggtaaaatc attaaagcct acgacggtga gattttttat catcgctaaa
    17641 aaaatccccc tcatcatgag ggggaaatgc agacaccttg ttatttttta ttattagcca
    17701 cttgctcgtc ttgcttgtta ttagtcgtat ttcacgttga ttaatgcggt tgcctccagt
    17761 gcgccagatt taactttgtt tgtatcgtag acgtagtaac tggctgttat cggaattgaa
    17821 accgttgtat ctgtaagttt tgactttgcc gcaatttctt ttaaatttgt gtatcctttg
    17881 ctgttatcag tgatatttaa aagtgtgact ggcgaaccat tactttcaag aataaatcct
    17941 acgccattat cttccgcacc tttcagtatt gtgttgctgt tggttaacaa gtcagaactt
    18001 gataaataca cctgcatttt ccgtgatgtt tgattttgtt gacctaataa atttttacaa
    18061 cgcagaataa tatccccttt tttactattt attgttgctt tgttacctgt ggctggtaat
    18121 tgtgaaacgg gaataccctc taaagtaatt aataaatcgt ccggtttgca ggttgtggtt
    18181 atcgggttgt atgacaaggt cagattaaag gaatagacac ctgcattttg tgccaatgca
    18241 tttctatagc tatttacaca tgcatcccat gacttgccac ctaataaaca cagtagaaaa
    18301 tgtactgcgg cactcccgcg tgtcgatgat gaagcactgg ataatgtcgc aacaccatta
    18361 atcatcactg aaccgccgcc ccccgcagaa acattcactt ttgcattact ggccgcaggt
    18421 gtcaccgtta ccgaataacc attggtgaaa ctggtctgat tatttgacaa cgtgatgtta
    18481 tttttattgg tccattcaaa atgtaaattt aatttaatgg tatcgttata aagtccaaca
    18541 ataatatccg acgggctcat aggggtgata gtatttgtac tcacgcatga cgaatcatta
    18601 aaattatgct catatgtcgc catttgtgtt tgagtaagtg caaaatcccc ctgaacaacc
    18661 aagttgtgct gaacagataa ctcactataa catgccgcat agctcacagg cataaccatc
    18721 atcattaata taaatagcat tatgcgaatt tccatagaac cacctgacta ttactggcaa
    18781 atataatttc tactttcatc aatctcttta ccgaaggtga ttgtgcatga aagtccttgt
    18841 tgcttatcaa ttgctacatt aaccgatggc ggtacttcat tggtgcgaat aaataactgg
    18901 cttccctgac cgacaacgcc aatattatga ccatggatat cattgacttc ataaccaaac
    18961 attaatggtt gcccatccgc tcttaacgct tttataaacc agggcttgcg ctgatcggta
    19021 tcaaaattaa ccagtacaac cgcgccgcga taaggggcgg caattttccg gttgccacgt
    19081 aattctgctt cgctatcgct ttgcgacaca tccagcatca ggtgattttc ccgataaggt
    19141 gtcattccgt cgtataccac cactccatta cggtttgttg tgcgatattt ttgcccattg
    19201 acataagcat ctttaattcc tggggcattc atcacagcaa acgtttcgga aagacggttc
    19261 gccagattaa cgccacccga ccaggcgaca atgcccccag aaacactggc tccagcctgt
    19321 cgataagtac tcgactgact ataactgcca ttcactgtcg caaccggcgc gttccaggtc
    19381 aaattcgccc cagctgtcgt ttcatttccc tgatgctgat aactcaggtt gaccccatag
    19441 ttaaactgat cccggcttcc aacggttcct gataatcccg tattatttga ggcaaacccc
    19501 tgatcatcaa acgtcgttga gttagacata tatatttgcc gacgaggcgt cgtaacgtca
    19561 tcaccccaat caaagggaat cgatataaaa atattaaatc gtttctcttc atgatgattc
    19621 tcgtcataag cctggcttgc cgcgagggta tagcttatcc gccgccagtt attggaataa
    19681 ctcaactgat aatccttact gctgccgcta cgtccccagt aatctcgcca taacgtactt
    19741 aaggacacag aaccccagcc ttctggcaat gactggctca tattggcaga aaagctattt
    19801 ttacggccaa aatcgttctg gtaataatcg gcaatgtcat agacatcgtt ttcatcacgg
    19861 cgataattat ctttattgtt tgcccaaacg tgatcattaa atgtccggta atcacgcgat
    19921 gaataacgcc aggccgcaag accaaaacgc gtcgacgttt ggctcacaaa tttgttgtag
    19981 gcaatttgat aactttgccc gtcaaacaca tcgccgttgt cttgtttact atgcgactta
    20041 gtggcatcga cggaaatggc accaatgcgt gtattccagc cagtccccaa agtaaacgcg
    20101 taataattat tcgcgaccat cgagccgcca tacagcgtca ataaattatt aaaaccatac
    20161 tgataaccca cctggacaaa ttcactttgt ttgctcgccc cttcaatatg gctacgaccc
    20221 gccgcaaaat catatttcga cacgccgggt tgcagcatat ttggcaccgc tgcataaggc
    20281 accagatagg tggttaccga accgtccgcc tctttcacgc tgacatcaag atctgctcca
    20341 ccaccggcca actgcaaatc tgtaatcgcg aacgggccag gaggaacctc tttctgataa
    20401 acgacaaaac cattctgttc aatagttacc agcgcgttac tctgagcaat cccctgcacc
    20461 cgtggcgtaa aattttgttt cgagttaggc aacatctgca tatcacgaaa caaccgcaca
    20521 cctctgaagc gaacagaatc aaaaatatcg cttgatgtgt acatatcacc cacgcgaagc
    20581 gtgccgagaa gttgggcaaa tccacgttcc agatacaggg tattgctttt ccacacccct
    20641 ggattgttat ttgttttact gaaactggca tcagaatgca gttgccaccc cagtaaattt
    20701 aacccgctgt taaaacgtac atatgtactc ttgttattac ccgacgcttt atagtcgctg
    20761 taatactgac tcagataata agaggtataa aacgcattaa taccccgctc ccagttttcc
    20821 ggtggaacat agccactttc cagttcttcc acccaggcct gcgggacact gaaatcgaga
    20881 cgaaaaaccc cgatatccca ggtatagctc ccaccctgaa caagttgctc aaatgttaaa
    20941 cattgcttac cgctggcgaa gttatcgcta ttaatgccta accgcttgat aacttctctt
    21001 gataaacatg tttcttgcgg gttgtcttta acaataatct catatttccc gcgccattgc
    21061 ttattgacat aaatatcgat gtcatactgc cccggtaagg gttgattatc atcaagacga
    21121 atatttgcaa cctgctggtc tttcattcca cctatcataa aatgggtatc aaaggtttct
    21181 tcagctgcat aagcttcaat gccgagcaat aacgctacga ttgctgatgc aagtggggtc
    21241 attctcaaca taggcagctc ctgcaattaa attttgtcac taatatagtt gccatggtca
    21301 tcgataatgg tcagatgcca gttatttgca ttattacttt tgacattaac actctgactt
    21361 tctaaggggg caatcataat agtttcataa ttgactttga cattattagc tttgacatcc
    21421 gaaatcgtca cccaattagc tgagtcattt tttatcacca aaccattgcc actgcgattt
    21481 accagcaatt ttttaaatgt cgctttattt accggagcaa tacccgctgg ccggtaaaac
    21541 aacttaattc tgttttgcat cgcaaacttc agtgcattct taccttcttg ctctggacta
    21601 tttggtggaa tatccagaac attcagataa aaaatgcttt ctttattagt gggcagttta
    21661 ttcggcataa ttttgatttt tacttgctgc ccggaatttg cccctatttt tgcaactggt
    21721 ggcgttaaca tgaaaggaac ctgaattttt tctggtggta acgacgtatc gccatcatca
    21781 atccacgcct gcagcagcga agaacgattt ccctggttca tcaactgcac cataacttct
    21841 ttattttctg ccgggtaaat aatgcgcgtc ccgtagataa caattccggc atgtgcagga
    21901 aggaccatag aaaaaatgag taaagataat aatcctttca ttttaatgcc tcttaaatta
    21961 aaaggccgcc atgggatagc ggccatgttt attacctgga gaaacttgca attttattta
    22021 ttaatcctgc gccacacgca taaccagaga agataacaca tcacctgatt gcactgagtt
    22081 atctgttagt ttcaggtatt ttgctttaaa cggaatagca tattgacctt ccgctgtttt
    22141 ataactctca atattaaaag gtgcagaaac atccaggaca tcgctgttat cacctaaata
    22201 gagatagtaa cccacggtat cgttgctact ggctatcgcc ttatcgttgc cggttatttt
    22261 gtcgttggta atcaacgaga gttttacacc agcaacttct ttcgggcagc taatttttaa
    22321 catgctgctg gttacaccga ctgcatcatc ataggtagaa tatttagctt taccttcaaa
    22381 gacagtggtt ggtacagtcg gcatattaat acttactgaa tcaccacccg cttcgaattt
    22441 acacggagat tctgcaatat ttcctttaat ggttaatgtt ccggtatcaa cgtctgcagc
    22501 aaatactcca gcgctcataa aaaaagaaga aaagacagcg gcagcaataa ttgaacgttt
    22561 cataatatgt tccttaataa aatttatttt tggttgttaa gagtctgtat ctcttggaaa
    22621 caaatttctc acatcaaaaa a
//
LOCUS       DAPOAV010000073        22540 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.073, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000073 DAPOAV010000000
VERSION     DAPOAV010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22540
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.073"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            7..1953
                     /gene="yegI"
                     /locus_tag="RN951_003205"
                     /pseudo
     CDS             7..1953
                     /gene="yegI"
                     /locus_tag="RN951_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416574.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase YegI"
     gene            complement(1966..3318)
                     /gene="yegD"
                     /locus_tag="RN951_003206"
     CDS             complement(1966..3318)
                     /gene="yegD"
                     /locus_tag="RN951_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416573.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDX2528169.1"
                     /translation="MFIGFDYGTANCSVAVMRDGKPQLLKMENDSTLLPSMLCAPTRE
                     AVSEWLYRHHDVPVDDNETQALLRRAIRYNREEDIDVTAKSVQFGLSSLAQYIDDPEE
                     VWFVKSPKSFLGASGLKPQQVALFEDLVCAMMLHIRQQAQAQLPDAITQAVIGRPINF
                     QGLGGDEANTQAQGILERAAKRAGFKDVVFQYEPVAAGLDYEATLQEEKRVLVVDIGG
                     GTTDCSLLLMGPQWRSRLDREASLLGHSGCRIGGNDLDIALAFKNLMPLLGMGGETEK
                     GIALPILPWWNAVAINDVPAQSDFYSSANGRLLNYLVRDAREPEKVALLQKVWRQRLS
                     YRLVRSAEESKIALSSVAETRASLPFISDELATLISQQGLESALNQPLARILEQVQLA
                     LDNAQEKPDVIYLTGGSARSPLIKKALTEQLPGIPIAGGDDFGSVTAGLARWAEVVFR
                     "
     gene            3452..4309
                     /gene="alkA"
                     /locus_tag="RN951_003207"
     CDS             3452..4309
                     /gene="alkA"
                     /locus_tag="RN951_003207"
                     /EC_number="3.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase 2"
                     /protein_id="HDX2528170.1"
                     /translation="MYTLNWQPPYDWSWMLGFLAARAVNGVETVADDYYARSLAVGEY
                     RGVVTAIPDIARHTLHINLSAGLEPVAAECLAKMSRLFDLQCNPQIVNGALGKLGAAR
                     PGLRLPGSVDAFEQGVRAILGQLVSVAMAAKLTARVAQLYGERLDDFPDYVCFPTPQR
                     LAAADPQALKALGMPLKRAEALIHLANAALEGTLPMTIPGDVEQAMKTLQTFPGIGRW
                     TANYFALRGWQAKDVFLPDDYLIKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEG
                     WQPDGTDEL"
     gene            complement(4347..7664)
                     /locus_tag="RN951_003208"
     CDS             complement(4347..7664)
                     /locus_tag="RN951_003208"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDX2528171.1"
                     /translation="MSKQSQHVLIALPHPLLHLVSLGLVSFIFTLFSLELSQFGTQLA
                     PLWFPTSIMMVAFYRHAGRMWPGIALSCSLGNIAASILLFSTSSLNMTWTTINIVEAV
                     VGAVLLRKMLPWYNPLQNLADWLRLALGSAIVPPLLGGVLVILLTPGDDPLRAFLIWV
                     LSESIGALALVPLGLLFKPHYLLRHRNPRLLFESLLTLAITLTLSWLSMLYLPWPFTF
                     IIVLLMWSAVRLPRMEAFLIFLTTVMMVSLMMAADPSLLATPRTYLMSHMPWLPFLLI
                     LLPANIMTMVMYAFRAERKHISESETRFRNAMEYSAIGMALVGTEGQWLQSNKALCQF
                     LGYSQEELRGLTFQQLTWPEDLNKDLQQVEKLISGEINTYSMEKRYYNRNGDVVWALL
                     AVSLVRRTDGTPLYFIAQIEDINELKRTEQVNQQLMERITLANEAGGIGIWEWELKPN
                     IFSWDKRMFELYEIPPHIKPNWQVWYECVLPEDRQHAEKVIRDSLQSRSPFKLEFRIA
                     VKDGIRHIRALANRELNKEGEVERLLGINMDMTEVKQLNEALFQEKERLHITLDSIGE
                     AVVCIDMAMKITFMNPVAEKMSGWTQEEALGVPLLTVLHITFGDNGPLMENIYSADTS
                     RSAIEQDVVLHCRSGGSYDVHYSITPLSTLDGSNIGSVLVIQDVTESRKMLRQLSYSA
                     SHDALTHLANRASFEKQLRILLQTVNSTHQRHALVFIDLDRFKAVNDSAGHAAGDALL
                     RELASLMLSMLRSSDVLARLGGDEFGLLLPDCNVESARFIATRIISAVNDYHFIWEGR
                     VHRVGASAGITLIDDNNHQAAEVMSQADIACYASKNGGQGRVTVYEPQQAAAHSERAV
                     MSLDEQWRMIKENQLMMIAHGVASPRIPQARNLWLISLKLWSCEGEIIDEQTFRRSFS
                     DPALSHALDRRVFHDFFQQAAKAVASKGLSIALPLSVAGLSSTTLVNELLEQLENSPL
                     PPRLLHLIIPADAILDHAESVQKLRLAGCRIVFSQVGRDLQIFNSLKVNMADYLLLDG
                     ELCANVQGNLMDEMLITIIQGHAQRLGMKTIAGPVVLPLVMDTLPGIGVDLIYGDVIA
                     DAQPLDLLVNSSYFAIN"
     gene            7982..8623
                     /gene="udk"
                     /locus_tag="RN951_003209"
     CDS             7982..8623
                     /gene="udk"
                     /locus_tag="RN951_003209"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HDX2528172.1"
                     /translation="MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVI
                     PEDCYYKDQSHLSMEERVKTNYDHPSAMDHSLLLEHLQALKRGSAIDLPVYSYVEHTR
                     MKETVTVEPKKVIILEGILLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRS
                     MDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE"
     gene            8715..9296
                     /gene="dcd"
                     /locus_tag="RN951_003210"
     CDS             8715..9296
                     /gene="dcd"
                     /locus_tag="RN951_003210"
                     /EC_number="3.5.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCTP deaminase"
                     /protein_id="HDX2528173.1"
                     /translation="MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTF
                     RGHTAAFIDLSGPKDEVSAALDRVMSDEIVLDEGEAFYLHPGELALAVTLESVTLPAD
                     LVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSF
                     EPLSGPAARPYNRREDAKYRNQQGAVASRIDKD"
     gene            9318..11171
                     /gene="asmA"
                     /locus_tag="RN951_003211"
     CDS             9318..11171
                     /gene="asmA"
                     /locus_tag="RN951_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane assembly protein AsmA"
                     /protein_id="HDX2528174.1"
                     /translation="MRRFLTTLMILLVVLVAGLSALVLLVNPNDFRDYMVKQVAARSG
                     YQLQLDGPLRWHVWPQLSILSGRMSLTVQGASQPLVRAYNMRLDVALLPLLSHQLSVK
                     QVMLKGAVIQLTPQTEAVRSEDAPVAPRGNTLPDLSDDRGWPFDISSLKVADSVLVFQ
                     HEDDEQVTIRNIRLQMEQDPQHRGSFEFSGRVNRDQRDLTISLNGTVDASDYPHDLMA
                     AIEQINWQLQGADLPKQGIQGQGSFQVQWQESHKRLSFNQISLTANDSTLSGQAQVTL
                     TEKPEWQLRLQFPQLNLDNLIPLNETANGENGAAQQGLSQSTLPRPVISSRIDEPAYQ
                     GLQGFTADILLQASNVRWRGMNFTDVATQMTNKSGLLEITQLQGKLNGGQVSLPGTLD
                     ATSINPRINFQPRLENVEIGTILKAFNYPISLTGKMSLAGDFSGADIDADAFRHNWQG
                     QAHVEMTDTRMEGMNFQQMIQQAVERNGGDVKAAENFDNVTRLDRFTTDLTLKDGVVT
                     LNDMQGQSPMLALSGAGTLNLAEQTCDTQFDIRVVGGWNGESKLIDFLKETPVPLRVY
                     GNWQQLNYSLQVDQLLRKHLQDEAKRRLNDWAERNKDSRNGKDVKKLLEKM"
     gene            complement(11623..13206)
                     /locus_tag="RN951_003212"
     CDS             complement(11623..13206)
                     /locus_tag="RN951_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416567.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HDX2528175.1"
                     /translation="MEWIADPSIWVGLVTLVIIELVLGIDNLVFIAILAEKLPPAHRD
                     RARITGLMLAMVMRLLLLTSISWLVTLTQPLFSFRSFTFSARDLIMLFGGFFLLFKAT
                     IELSERLEGKDSNNPTQRKGAKFWGVVTQIVVLDAIFSLDSVVTAIGMVDHLLVMMAA
                     VVIAISLMLMASKPLTQFVNSHPTIVILCLSFLLMIGFSLVAEGFGFVIPKGYLYAAI
                     GFSVMIEVLNQLAIFNRRRFLSANQTLRQRTTEAVMRLLSGQKEDAELDAETASMLLD
                     HGNQQIFNPQERRMIERVLNLNQRTVSSIMTSRHDIEHIDLNAPEEEIRQLLERNQHT
                     RLVVTDGDDAEDLLGVVHVIDLLQQSLRGEPLNLRVLIRQPLVFPETLPLLPALEQFR
                     NARTHFAFVVDEFGSVEGIVTLSDVTETIAGNLPNEVEEIDARHDIQKNADGSWTANG
                     HMPLEDLVQYVPLPLDEKREYHTIAGLLMEYLQRIPKPGEEVQVGDYLLKTLQVESHR
                     VQKVQIIPLRKDGEMEYEV"
     gene            13966..14856
                     /gene="galF"
                     /locus_tag="RN951_003213"
     CDS             13966..14856
                     /gene="galF"
                     /locus_tag="RN951_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GalU regulator GalF"
                     /protein_id="HDX2528176.1"
                     /translation="MANLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEIVLVTHSSKNAVENHFDTSYELEALLEQRVKRQLLAEVQAICPPGVTIMNV
                     RQAQPLGLGHSILCARPVVGDNPFVVLLPDIILDGGTADPLRYNLAALIARFNETGRS
                     QVLAKRIPGDLSEYSVIQTKEPMVAEGQVARIVEFIEKPDEPQTLDSDLMAVGRYVLS
                     ADIWAELERTEPGAWGRIQLTDAIAELAKKQSVDAMLMTGESYDCGKKMGYMQAFVTY
                     GMRNLKEGAKFRESIKKLLA"
     gene            15249..15841
                     /locus_tag="RN951_003214"
                     /pseudo
     CDS             15249..15841
                     /locus_tag="RN951_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227873.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(15966..16663)
                     /locus_tag="RN951_003215"
                     /pseudo
     CDS             complement(15966..16663)
                     /locus_tag="RN951_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
     gene            complement(16827..16949)
                     /locus_tag="RN951_003216"
     CDS             complement(16827..16949)
                     /locus_tag="RN951_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528177.1"
                     /translation="MMIILTGSIFTAVEENLCAAASGFSDATAPGLTATSALTT"
     gene            17240..18673
                     /locus_tag="RN951_003217"
     CDS             17240..18673
                     /locus_tag="RN951_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule assembly Wzi family protein"
                     /protein_id="HDX2528178.1"
                     /translation="MIKIARIAVTLGLFSSLGAQAYAAGLVVNDNDLRNDLAWLSDRG
                     VIHLSLSTWPLSQEEIARALKKAKPSYSSEQVVLARINQRLSALKADFLVIGYTSTDQ
                     PGTPQGFGQTQPADNSLGLAFNNSGEWWDIHLQGNVEGGERISNGSRFNANGAYGAVK
                     FWNQWLSFGQVPQWWGPGYEGSLIRGDAMRPMTGFLMQRAEQAAPETWWLRWVGPWQY
                     QISASQMNQYTAVPHAKIIGGRFTFTPFQSLELGASRIMQWGGEGRPESFSSFWDGFT
                     GKDNTGTDNEPGNQLAGFDFKFKLEPTLGWPVSFYGQMIGEDESGYLPSANMFLGGVE
                     GHHGWGKDAVNWYVEAHDTRTNMSRTNYSYNHHIYKDGYYQQGYPLGDAMGGDGQLIA
                     GKVELITEDNQRWSTRLVYAKVNPENQSINKAFPHADTLKGVQLGWSGDVYQSVRLNT
                     SLWYTNANNSDSDDVGASAGIEIPFSL"
     gene            18819..19955
                     /locus_tag="RN951_003218"
     CDS             18819..19955
                     /locus_tag="RN951_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016161490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein"
                     /protein_id="HDX2528179.1"
                     /translation="MKKKLVRFSALALAIGFLSGCTVIPGQGLNTLRKNVVELPDSDY
                     DLDKLVNVYPMTPGLIEQLRPETVLARPNPQLDNLLRSYEYRIGVGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNSDGTIFYPYIGKVQVAGKTLSQVRQDIASRLTTYIESPQ
                     VDVSVAAFRSQKAYVTGEVEKSGQQPITNIPLTVMDAINAAGGLSENADWRNVVLTHN
                     GKDTKISLYALMQKGDLTENRLLYPGDILFVPRNDDLKVFVMGEVGKQSTMKMDRSGM
                     TLAEALGNAEGMSQAFSDATGVFVIRQLKGDKQGKIANVYQLNAQDASAMVLGTEFQL
                     QPYDIVYVTTAPLVRWNRVISQLVPTISGVHDMTETVKFVKDMQ"
     gene            19955..20389
                     /locus_tag="RN951_003219"
     CDS             19955..20389
                     /locus_tag="RN951_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152837.1"
                     /note="Wzb shows phosphatase activity towards the
                     autophosphorylated Wzc protein, which induces colanic acid
                     biosynthesis; catalyzes the phosphorylation of UDP-glucose
                     dehydrogenase, an enzyme involved in colanic acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein tyrosine phosphatase"
                     /protein_id="HDX2528180.1"
                     /translation="MFDSILVVCTGNICRSPIGERFLQKALPTKKIDSAGTNALIGHK
                     ADDSAIKIAEKHGISLAEHVGRQFTSFIGRQYDLILVMERYHIEKIGQIAPELRGKTM
                     LFGQWLNQKEIPDPYRKSDEAFASVYQLIELAGLRWVEKLGA"
     gene            20409..>22540
                     /locus_tag="RN951_003220"
     CDS             20409..>22540
                     /locus_tag="RN951_003220"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014838955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase"
                     /protein_id="HDX2528181.1"
                     /translation="MSSVKNRTVEKEADEIDLGRLVGELIDHRKLIISVTALFTLIAL
                     LYALFATPIYQADALLQVEQKQGNAILNSLSQMLPDSQPQSAPEIALLQSRMILGKTV
                     DDLNLQAKIEQSYFPLLGKGWARLVGEKKGILVVSRLYLSSDSNTEIPKLKLKVKDAN
                     NYIVTFNDHEFEGKVGVLLDSNGISLKVDSIEAKPGTEFVISYVSKLQAITDLQEIFS
                     VADQGKDTGILSLSLTGPDPLLLEKTLNSISNNYLAQNVARQAAQDAKSLEFLNQQLP
                     KVRNDLDIAEDKLNQYRRQKDSVDLSLEAKSVLEQIVNVDNQLNELTFRESEISQLYT
                     KEHPTYKALMEKRKTLQDEKAKLNERVSAMPKTQQDILQLSRDVDSGQAVYMQLLNRQ
                     QELNIAKSSAIGNVRIIDDAVSQPEPVKPKKIIIVLVGIVLGGMVSIGIVLLRIFLRR
                     GIESPEQLEELGINVYASIPISETFANKALQNTKLRRKAGSEYQSFLAVDNPADLAIE
                     AIRGLRTSLHFAMMEARNNVLMISGASPNVGKTFVSSNLAAIIAQTGKKVLFIDTDMR
                     KGYTHKLFNLSNDNGLSDVLSGKIEVSKAIKKVSSAGFDYISRGMVPPNPAELLMHRR
                     LGELITLVSQSYDIVILDTPPILAVTDAAIIGNYVGTTLLIARFEQNTTKEIEVSFKR
                     FEQSGVIVKGCILNGVVKKASSYYSYGY"
BASE COUNT         5724 a         5466 c         5877 g         5473 t
ORIGIN      
        1 aacattatga agacaaatat aaaagtattt acatcaacag gtgaaatgac cactctcggt
       61 cttgaactgg gcaaaggcgg tgaaggcgcg gtttatgata tcaatgagtt tgtcgatagc
      121 gtcgccaaga tttatcacac gccgccaccc gccttaaaac aggacaaact tgcctttatg
      181 gctgcgacag ctgacgcgca attgttgaat tatgtcgcct ggccgcaggc aacgcttcac
      241 ggtggacgag gcggaaaagt tatcggtttt atgatgccaa aagtttctgg taaagaaccg
      301 attcatatga tctatagccc ggcacatcgt cgtcaacgtt accctcattg tgcgtgggat
      361 tttctactct atgttgcgcg caatattgct tcatcttttg ctacggttca cgagcacggg
      421 cacgtcgtgg gtgacgtaaa ccagaacagc tttatggtag atcgcgacag caaagtggtg
      481 ttgattgata gcgactcctt tcagattaac gccaatggca cgctgcattt atgcgaagtc
      541 ggcgtgtcgc attttacgcc gccagagcta caaaccttgt cgtcatttat cggctttgaa
      601 cgcacagaaa atcacgataa ttttggcctt gcgttgctga tttttcacgt cttgtttggt
      661 gggcggcatc cttattctgg tgtgccgctt atctctgatg cggggaatgc actggagacg
      721 gatattgccc atttccgtta tgcctacgcg tcagataatc agcgacgtgg tttaacaccg
      781 ccgccacgat ctattccgct gtcgatgtta ccgggtgatg ttgaagccat gtttcagcag
      841 gcattcacgg aaagtggcgt ggcaaccggg cgtccgacgg caaaagcgtg ggtagcggca
      901 cttgatttac tacgccaaca gttaaagaaa tgtaccgttt cggcaatgca tatttacccc
      961 ggtcatttga ccgactgccc gtggtgtgcg ctggataatc aaggcgttat ctattttatt
     1021 gatctcggcg aagaggtcat taccaccagc ggtgattttg tgctggcgaa agtctgggcg
     1081 atggtgatgg cgtcagtagc accgccagca ttgcaattgc cattacccga tcatttccaa
     1141 ccgactggca ggccgcttcc tttaggcctg ttacggcgtg aatacatcat tctgattgag
     1201 atcgcactgt cagcgttatc gctgctgctt tgcggccttc aggtagaacc gcgttatatc
     1261 attttggttc ccgtgctggc ggctatctgg attattgaca gccttacaag caaagcgtac
     1321 aaagcagaag tccagcgacg aagagaggct tttaatcgcg caaaaatgga ctatgaccat
     1381 ttagtcagcc agatccaaca gttgggcggg ctggaaggtt ttatcgccaa acggacgatg
     1441 ctcgaaaaaa tgaaggacga aattcttggg ttaccggaag aggagaaacg cgctctggca
     1501 gcacttcagg acaacgcaag ggaacggcag aagcagaagt ttctggaggg attttttatc
     1561 gatgctgcct ctattcccgg cgtaggccca gcgcgtaaag cggcgttacg gtcttttggt
     1621 attgaaaccg ccgcagacgt tacccgacgg agcgttaagc aagtaaaagg ttttggtgat
     1681 catctgaccc aggcggttat cgactggaaa gcgagttgcg aacgccgttt tgttttcagg
     1741 ccgaacgaag cggtaacgcc tgcagacaga caagcggtaa tggcaaaaat ggccgccaaa
     1801 cgacatcggc tggaatcggc gctgactgtc ggtgcgacag agttgcagtg attccgcctt
     1861 catgctccag cacggaccat gccgttgatg gaaccgctac gtcaggcggc agaaaaactg
     1921 gctcaggcgc aggctgattt aagccgttgc tgagccagtt ttcaattaac gaaacaccac
     1981 ttccgcccag cgtgccagcc cggcggtgac ggagccaaag tcatcgccac ctgcaatcgg
     2041 aatgcccggc aactgttctg tcagcgcttt tttaatcagc ggtgaacggg cgctaccgcc
     2101 ggtcagatag ataacatccg gtttttcctg ggcgttatcc agcgccagtt gcacctgttc
     2161 cagaatccgc gccagtggct ggttgagggc gctttccagc ccttgctggc taatcagcgt
     2221 agccagttca tcgctgataa acggcagtga ggcgcgggtt tccgctacgc ttgaaagcgc
     2281 aattttgctc tcttctgcgc tacgtaccag gcgatagctt aaacgctgac gccagacttt
     2341 ctgtaacagg gccacttttt ccggttcgcg ggcatcgcgt accagatagt taagcagacg
     2401 accgttggca ctactgtaga aatcactttg cgcaggtacg tcgttgatgg caaccgcatt
     2461 ccaccacggc agaatcggca gggcgatgcc tttttcggtt tcgccaccca tgcccagtaa
     2521 cggcatcagg tttttaaacg ccagcgcgat atccagatcg ttaccgccaa tacggcaacc
     2581 actgtgaccc agcaggctgg cttcacgatc gagacgcgaa cgccactgcg gccccatcag
     2641 cagcaatgaa cagtcagtcg taccaccgcc gatatccacc accagcaccc gtttttcttc
     2701 ctgcaaggtg gcttcgtaat ccagcccagc cgcgaccggc tcgtactgga ataccacatc
     2761 cttaaacccg gcacgctttg ccgcgcgttc cagaatccct tgcgcctggg tgtttgcttc
     2821 atcgccgccc agcccctgga agttgatcgg gcgaccaatc accgcctgag taatcgcatc
     2881 cggcagctgc gcctgcgcct gctggcgaat atgcaacatc attgcgcaga ccagatcctc
     2941 aaacagcgct acctgctgcg gttttaagcc gctggcaccg aggaatgatt ttggtgattt
     3001 cacaaaccac acctcttctg gatcatcaat gtactgtgcc agtgaggaaa gaccgaactg
     3061 cacgcttttc gccgtaacat cgatatcttc ttcgcggtta taacgaatcg cccgacgcaa
     3121 cagcgcctgc gtttcattgt cgtctaccgg aacatcatga tggcggtaca gccattcgct
     3181 taccgcttca cgcgttggcg cgcaaagcat tgaaggcagc agcgtgctgt cgttttccat
     3241 tttcagtaat tgtggcttac cgtcgcgcat gaccgccact gaacagtttg ctgtaccgta
     3301 atcaaaacca ataaacacga aataatcccc atgccggtga agaaggggcg tgactttagc
     3361 gaaatgttgc cgtcgcgaca accggaatat gaaagcaaag cgtagcgtct gaataacgtt
     3421 tatgctgaaa gcggattaac aaggagatgc gatgtatacc ctgaactggc agccgccata
     3481 tgactggtcg tggatgttgg gatttctcgc cgcccgtgcg gtgaacggtg tggaaacggt
     3541 cgctgacgat tattatgccc gtagtctggc ggtgggcgaa tatcgcggcg tggtgactgc
     3601 tattccggat atagcccgcc atactctgca cataaattta agtgcaggtt tagaacctgt
     3661 tgccgcagag tgtctggcga aaatgagccg cctgtttgat ctgcaatgta acccgcagat
     3721 tgttaacggt gcgttgggca agttaggcgc ggcgcggccc ggattgcgtt tacccggcag
     3781 tgttgatgct tttgagcagg gcgtgcgggc gattttaggc caactggtga gcgtggcgat
     3841 ggcggcaaaa ttgaccgcca gagtggcaca gctttatggc gaacggctgg atgattttcc
     3901 ggattatgtc tgcttcccca cgcctcagcg gctggcagca gcagatccgc aggcattaaa
     3961 agcgttaggt atgccgttga aacgggcaga ggcgctgatt catctggcaa atgcggcgct
     4021 ggagggcacc ttaccaatga caataccggg cgatgtggag caggcgatga aaacgctgca
     4081 aacttttccg ggtatcgggc gctggacggc gaattatttc gccttgcgcg gctggcaggc
     4141 gaaagatgtt ttcctgccgg atgattatct gattaaacag cgatttccgg gaatgacacc
     4201 ggcacaaatc cgccgttatg ccgaacgctg gaagccctgg cgttcttatg cgctgttgca
     4261 tatctggtat acggaaggct ggcaaccaga cggaacggac gaattgtagg cctgatacgc
     4321 cgcatcaggc gatggggaag cacgccttag ttaatcgcga aataactgct attcaccagc
     4381 aaatccagcg gttgggcatc ggcaatcaca tcaccataaa tcaaatcgac gccgatgcca
     4441 ggaagcgtat ccatcaccag gggtaaaact actggcccgg cgatggtctt catcccgagc
     4501 cgctgagcgt gcccctgaat gatcgtaatc agcatctcat ccatcaaatt tccctgcacg
     4561 ttggcgcata actcaccatc aagtagtagg taatctgcca tatttacttt cagcgagttg
     4621 aagatttgca gatcgcggcc cacctgactg aatacgatcc gacatcccgc cagccgcagt
     4681 ttttgcacgc tttctgcgtg atctaaaatc gcgtctgccg gaataatcag atgtaataac
     4741 cgtggtggta aagggctgtt ttccagctgt tcaagcagtt catttaccag tgtggtgcta
     4801 ctcaaaccgg caacggaaag ggggagggcg atgcttaagc ctttactggc aaccgctttt
     4861 gcggcctgct ggaaaaaatc gtggaatacc cgtcggtcaa gagcatggct aagtgccgga
     4921 tcgctgaagc tacgtcgaaa tgtttgttca tcaataatct cgccttcgca actccagagc
     4981 ttaagtgaaa tcagccacaa attacgcgct tgcgggatcc gcggcgaagc gacaccgtgg
     5041 gcgatcatca tcaactgatt ctctttaatc atccgccact gttcatcaag cgacatcacc
     5101 gcccgttcgc tatgtgcggc agcttgctgc ggttcgtaaa ccgtcacccg gccctgtcca
     5161 ccatttttgg aggcataaca ggcgatatca gcctgcgaca tcacttcagc cgcctgatga
     5221 ttgttgtcat caatcaaggt aatcccggca ctggcaccta cccgatgtac acgtccttcc
     5281 cagataaagt gatagtcatt tacggcgctg ataatgcgtg tagcgataaa acgcgcactt
     5341 tcgacattac aatctggcag cagcagacca aattcatcgc caccgagtcg cgccagcacg
     5401 tcgctggagc gcagcatact cagcatcaat gacgcaagtt cgcgcaacaa agcgtcgcca
     5461 gcggcgtgcc cggcgctgtc attcaccgct ttaaagcgat caagatcgat aaacaccagt
     5521 gcatgtcgct gatgtgtact gtttaccgtt tgcagcagga tgcgtagttg cttctcaaaa
     5581 ctggcgcgat tggcgagatg cgtcagtgca tcatgggagg cgctgtagct cagctggcgc
     5641 agcattttgc gcgattcggt gacgtcctga atcaccagaa ccgaaccaat attgctgccg
     5701 tccagagtac ttaacggcgt aatactgtaa tgcacgtcgt agctgccgcc gcttcggcag
     5761 tgcaacacca catcttgttc aatcgcggaa cgtgaggtgt cggcactgta aatgttctcc
     5821 attaatggtc cgttgtcgcc aaaagtaata tgcaacaccg tcaggagtgg aacacctaac
     5881 gcttcttcct gcgtccagcc gctcatcttc tccgccaccg gattcataaa ggtaattttc
     5941 atcgccatat caatacagac cacggcttca ccgatggaat caagcgtaat gtgcaggcgc
     6001 tctttttcct gaaacaatgc ctcgttaagc tgtttaacct cggtcatatc catattaatg
     6061 ccgagcagac gttcgacttc gccttcttta ttcagttccc ggttggcgag ggcgcggata
     6121 tggcggatgc catctttcac ggcaatgcga aattccagtt taaagggaga gcgcgattgc
     6181 aatgaatcgc gaatcacttt ttcggcgtgc tggcgatctt ccggcagcac gcactcgtac
     6241 cacacctgcc agtttggttt gatatgcgga ggaatttcat acagctcgaa catccgctta
     6301 tcccagctaa aaatattcgg cttaagctcc cactcccaga tgccaatccc gcccgcttcg
     6361 ttagccagcg tgatgcgctc catcagttgc tgattcacct gttcggtgcg ttttagctcg
     6421 ttaatgtctt caatctgagc gataaaatag agcggcgtac catcggtgcg gcgcaccagt
     6481 gagacggcaa gcaacgccca gacaacatcg ccattgcggt tgtagtagcg tttttccatt
     6541 gaataggtgt ttatttcacc gctgatcagc ttttcaacct gttgcagatc tttattgaga
     6601 tcctccggcc aggtcagttg ctgaaaggtg agtccgcgca gttcttcctg actgtaaccg
     6661 agaaactggc agagcgcttt gttggattgc agccattgcc cctcggtgcc cactaatgcc
     6721 atgccgatgg cggaatattc catcgcgttc cgaaagcggg tttcgctttc ggaaatgtgt
     6781 ttgcgttccg cacgaaaggc atacatcacc atggtcatga tgttggcggg cagcaggatc
     6841 agcaaaaacg gtagccaggg catatggctc atcaggtatg tacgcggcgt agcaagcagg
     6901 gagggatccg cggccatcat cagtgacacc atcatcaccg tggtaaggaa gatcaaaaag
     6961 gcttccattc gtggcaggcg cacggcgctc cacatcaaca gcacaataat gaaagtaaaa
     7021 ggccacggca gatacagcat cgaaagccag cttaacgtca gtgtgatggc taacgtgagc
     7081 agcgactcaa aaagcaaccg tgggttgcga tggcgcagca gatagtgtgg tttaaataac
     7141 aatcccagcg gcaccagtgc cagtgcgccg atggattctg acagtaccca tatcaaaaat
     7201 gccctgagag gatcgtctcc gggcgtcagc aggataacca gaacaccccc taacagaggt
     7261 ggaacaatgg cgctgccgag tgccagacgc agccagtcag ccagattttg caatgggtta
     7321 taccacggca gcattttacg cagtagcact gccccgacca cggcttcaac aatattgatg
     7381 gtcgtccagg tcatgttcag cgagctggtg gaaaaaagca ggatggatgc ggcgatattt
     7441 cccagcgagc agctcagcgc aatccccggc cacatgcgcc cggcatggcg ataaaacgcc
     7501 accatcatga tggacgtcgg gaaccacagt ggggcgagtt gggtgccaaa ctgcgaaagc
     7561 tcaagcgaga aaagggtaaa gataaacgag actaaaccta aactgaccag gtgaagcagc
     7621 gggtggggca gggcaattaa tacatgctgt gattgtttgc tcattaccgc tttatccgca
     7681 agaccaggtc gccagtattc gtttctgtgt ttatgctagt acaaaagttt tacattttat
     7741 atgcgaattg ctcataaagt gacgtaaagg cggataattt gcgcaacggc gtataacatt
     7801 ttttaccttg tataaaactg atcaacgtaa tttgccaccg ggaattcttc gtcaacaatt
     7861 aactctgagc gcgcggcaac gctattcgac tggtatcagg cggatgaaat ccctataatt
     7921 gccgcgtttg gcgcttcgtc gcccccttcc taacatccag gttaatcagg tcgctaaata
     7981 tatgactgat cagtctcatc agtgcgtcat tatcggtatc gctggcgcat cggcttccgg
     8041 caagagtctt attgccagta ccctttatcg tgaattacgt gagcaagtcg gtgatgaaca
     8101 catcggcgta attcccgaag actgctatta caaagatcaa agccatctgt cgatggaaga
     8161 acgcgttaag accaactacg accatcccag cgcgatggat cacagcctgc tgcttgagca
     8221 tttacaagca ttgaaacgcg gctcggccat tgacctgccg gtttacagct atgttgaaca
     8281 tacgcgtatg aaagaaacgg tgacagttga gccgaagaaa gtcatcattc tcgaaggcat
     8341 tttgctgctg acggatgcgc gtttgcgtga cgaacttaac ttctcaattt tcgttgatac
     8401 cccgctggat atctgcctga tgcgccgcat caagcgtgac gttaacgagc gtgggcgttc
     8461 aatggattca gtgatggcgc aatatcaaaa aaccgtgcgc ccgatgttcc tgcaattcat
     8521 tgagccttct aaacaatatg cggacattat cgtgccgcgc ggcgggaaaa accgcatcgc
     8581 gatcgatata ttgaaagcga aaataagtca gttctttgaa taagcttgat aaattgtgta
     8641 ccgttcagtg ataacctggt atgcccttga cgtaattggc gttaagggag tgatgcgcga
     8701 aaggagaaaa tgccatgcgt ctgtgtgacc gagatattga agcctggctt gatgaaggcc
     8761 gtttgtcgat caacccacgt ccgccagtgg agcgtattaa cggcgcgacg gtggatgtgc
     8821 gcctgggcaa taaatttcgt accttccgtg gtcacacggc agcgtttatc gatctgagcg
     8881 gtcccaaaga tgaagtgagc gccgcgcttg accgcgtgat gagcgatgaa atcgtgctcg
     8941 acgagggcga ggcgttttat cttcacccag gagagctggc gctggcggtg acgctggagt
     9001 cggtgacgct gccagccgat ctggtgggct ggctggacgg gcgttcttca ctggcgcgtc
     9061 tggggctgat ggtgcacgtc accgcgcacc gtatcgatcc gggctggtct ggctgcattg
     9121 tgctggagtt ttacaactcc ggtaagctgc cgctggcgct gcgtccgggc atgttaattg
     9181 gtgcgctgag ctttgagccg ctctccggcc cggcggcgcg accttacaac cgccgtgaag
     9241 atgcgaaata tcgcaaccag cagggcgcgg tagccagccg aatcgataaa gactaattca
     9301 ggcctattga ggataccatg agacgatttc tgacgacgct gatgatactc ctggtcgtgc
     9361 tggtggccgg gttatctgcg ttagtattgc tggtgaatcc gaatgatttc cgcgactata
     9421 tggtcaagca agttgctgca cgtagcggtt atcaattgca gctcgacggg ccactgcgtt
     9481 ggcacgtctg gccgcagctt agtatcctct ccgggcgaat gtctctcacc gtccagggcg
     9541 caagccagcc actggttcgc gcctacaaca tgcgtctgga cgtggcgctt ttaccactac
     9601 tgagtcatca actgagcgtt aagcaggtga tgctaaaggg ggcagtgatc caactgacgc
     9661 cgcagacgga agctgtgcgc agtgaagacg ctccggttgc accgcgcggc aataccttgc
     9721 cggatctgtc agacgatcgc ggatggccgt ttgatatatc cagtcttaag gtggcggaca
     9781 gcgttctggt gttccagcat gaagatgacg agcaggtgac aatccgcaat atccgcctgc
     9841 aaatggaaca agatccccaa catcgtggct catttgagtt ctccgggcgg gttaatcgcg
     9901 atcagcgcga tctcacgata tcccttaacg gtacggtgga tgcttctgat tatccgcatg
     9961 atttaatggc ggctattgaa caaattaact ggcagttgca gggtgccgat ttaccaaaac
    10021 aaggtattca ggggcagggg agtttccagg tccagtggca ggagtcacat aaacgccttt
    10081 catttaacca aattagtttg accgccaatg acagtacgct gagcgggcaa gcacaggtca
    10141 cgttgacaga gaaaccggaa tggcagctga gactgcaatt cccgcaactg aatcttgaca
    10201 acctcatccc ccttaatgaa acagcgaatg gtgagaacgg tgccgcgcag caagggctga
    10261 gccaatcaac gttgccgcgc ccggtcattt cttcgcgtat tgatgaaccg gcctatcagg
    10321 gactgcaagg ctttacggct gatattttgt tgcaggccag taacgtgcgc tggcgcggaa
    10381 tgaattttac agatgttgcc acgcaaatga ccaacaagtc gggtttgctg gaaattactc
    10441 aactgcaggg caaacttaac ggtggacagg tttcactgcc gggcacgttg gacgcgacat
    10501 caataaatcc gcggataaac ttccagccac ggctggaaaa cgttgagatt ggcaccattc
    10561 tgaaggcgtt taactatccg atttcgttga ccggaaagat gtcactggct ggtgatttct
    10621 ccggtgctga catagatgcc gacgcattcc gccacaactg gcaaggacag gcacatgtcg
    10681 aaatgaccga cacacgcatg gaagggatga acttccagca gatgattcag caagcggtag
    10741 aacgtaatgg tggtgatgtg aaggccgctg aaaacttcga taacgtgacg cgtcttgacc
    10801 gctttaccac cgatttgacg ttgaaggatg gcgtcgtgac gttaaacgac atgcaaggtc
    10861 aatcgcccat gctggcgctt tccggggctg gtacgttgaa tctggcggag caaacctgcg
    10921 acacccagtt tgatattcgg gtcgtgggtg gctggaacgg agaaagcaaa ctgattgatt
    10981 tcctcaaaga aacgccagta ccgctgcggg tttatggcaa ctggcagcaa cttaattaca
    11041 gcctgcaagt ggatcagtta ctgcgtaaac atctacagga tgaagcaaaa cgccgtctta
    11101 acgactgggc cgagcggaat aaagattccc gcaatggcaa agatgtgaag aagttgctgg
    11161 agaagatgta ggttaccagg tgacctgtcc tgtaggcctg ataagacgcg taaagcgtcg
    11221 catcaggcgt tcgtggcggc accattatat tctgaatatg taagatcgaa ggctgttccg
    11281 ttcacttgat gttcctcgct actatggaac gctcaagccg gtgaacgtgc cagggtggct
    11341 caatcgccac caccctggca acccgggctc ccggcggtaa atcgccgctg gcgtggttcc
    11401 ctcatcttat tcctttcggc tatcgggtac gggcgcgagg taacatcact gtaaaacgcg
    11461 ccctcagccc acatccatgt gggctgcccc ggcctacagg aaacgattcg gcgatttaca
    11521 gccggaccca cacccccgct gtgatgtcca tgtaccacag acaacgcttc attgctgaag
    11581 ttataaggcg ttacgcagca ttgggtaaaa tggccgatac catcacacct cgtactccat
    11641 ctcgccatcc ttacgcagcg gaataatctg caccttctgc acgcgatggc tttctacctg
    11701 caacgtttta agcaaataat cccccacctg aacttcttcg ccaggttttg gaatacgctg
    11761 caaatattcc atcaatagcc cggcaatggt gtgatattca cgtttttcat ccagcggcag
    11821 cggcacatat tgcaccagat cttccagcgg catatgacca ttcgccgtcc aggaaccgtc
    11881 cgcatttttc tgaatatcat ggcgggcgtc gatctcttcc acttcgttcg gtaagttacc
    11941 ggcaatggtt tcagtgacgt cacttaatgt cacaatccct tccaccgagc caaactcatc
    12001 cactacaaaa gcaaagtgcg tgcgggcatt acggaactgc tccagggcag gtaacaacgg
    12061 caaggtttcc gggaacacca gcggctggcg aatcaacacc cgcaggttga gcggttcgcc
    12121 gcgcagtgac tgttgtaaca ggtcgataac gtgaacaaca ccgagcaaat cttctgcgtc
    12181 atcgccatca gtaacgacca gccgcgtatg ctgatttcgc tccagcaact ggcggatttc
    12241 ttcttccggc gcgttgagat cgatatgctc aatatcgtgg cgcgacgtca taatgctgct
    12301 gacggtacgc tggttaagat taagtacccg ctcaatcatc cgccgttcct gcggattaaa
    12361 gatctgctgg ttaccatgat ccagcagcat ggacgcggtt tcggcgtcca gttccgcatc
    12421 ttctttttgc ccgctaagca ggcgcatgac cgcttcggta gtccgctggc gcagcgtctg
    12481 gttagcggaa agaaaacgtc tccggttaaa gatagccaac tgattgagca cctcgatcat
    12541 caccgagaaa ccaatggcag cgtacagata gcctttcgga atgacgaagc cgaaaccttc
    12601 cgccaccagg ctaaagccaa tcatcaacag gaagcttaag cagagaataa cgatcgtcgg
    12661 atgactgtta acgaactggg ttaacggctt gctggccatc aacatcaggc tgatagcgat
    12721 aaccacggcg gccatcatga ccagtaaatg gtcgaccatc ccaatggcgg taaccaccga
    12781 gtcgagtgag aagatggcgt ccagtaccac aatttgtgtc accacccccc agaacttcgc
    12841 acctttgcgt tgtgtggggt tattgctgtc ttttccttcc agccgttcgc tcagctctat
    12901 tgtggctttg aacaacagga agaaaccacc aaacagcatg attaagtcgc gggcgctaaa
    12961 ggtaaacgag cggaagctga acagcggttg agtcagagtg accagccagg agatagaggt
    13021 cagcagcagg agacgcatca ccatcgccag catcaggcca gtgatccgcg cgcggtcgcg
    13081 atgggcggga gggagcttct cggcgaggat agcgataaag accaggttat cgatacccaa
    13141 caccagttcg ataatcacca gcgtgacgag acctacccag attgacggat cggcaatcca
    13201 ttccatatgt attaaaacct gtacgactgc ggtatgtgtt accacgatca tggataagat
    13261 tagtctaaaa tgcaataacg acgcggacat cgctctgccg tgggtggata tatttccagc
    13321 ggattaagcg aaccgataag aattatgttc cggaaaataa cagtgaaaaa taacaccatg
    13381 gcggctacca tggaataagc ttgccgatat cagaacttta tccgctgcgt ttcagcgagg
    13441 gcggcaaaag ggcttcctcc cgcggttcgt cacggcgagc gctgatgcgc agagcagaag
    13501 cgaagcgcga agcccgctca caaaaccggc ataattcata ttatgaagtg agtgcagaat
    13561 agggcggatc gcagttcacc gccgcggatt caggctaata tgacgtcata tccggctgtt
    13621 tatactgaag tatattgcct ggcgaaattt attatctata tatattcttt tcgggcatac
    13681 gcgcggcggg tccggcgtcc aacaggcccc gatagacggg catctcagcc acatcgtgcg
    13741 gagcaaagga acgagccgct gaataacctg aacgagaata agattattct cagttctaac
    13801 tgttggtaaa agggcgtttt gtgtattctt ttacgtgaca gtgaatttaa gaatttggcg
    13861 ggcatatgcc cgggcagtat ccgtgtatta tcagtttcaa tggatttgtg acatgtacaa
    13921 ttttgcaaaa ccgcgtgttt tgcaaccaaa caggtgaaga tgaatatggc gaatttgaaa
    13981 gcggttattc cggtcgcagg actaggcatg catatgctgc cggccacaaa ggcaattcca
    14041 aaggagatgc tgccgatcgt tgataagcca atgattcagt acatcgttga cgaaatcgtc
    14101 gccgccggga tcaaagagat tgttctggtg acgcactcct cgaagaacgc ggtggaaaac
    14161 cacttcgaca cctcctatga gctggaagcc ctgctggaac agcgcgtgaa gcgccagcta
    14221 ctggcggaag tgcaggccat ttgcccgccg ggcgtgacca tcatgaacgt gcgtcaggcg
    14281 cagccgttgg gcctgggaca ttccatcctc tgcgcccgcc cggtagtcgg cgacaacccg
    14341 tttgtggtgc tcctgccgga tatcatcctt gacggcggca ccgctgaccc gctgcgctat
    14401 aacctcgcgg ctttgatcgc ccgctttaac gaaaccggcc gcagccaggt gctggcgaaa
    14461 cgcataccgg gcgatctctc cgaatactcc gtcatccaga ccaaagagcc tatggtggct
    14521 gaaggccagg tggcgcgtat cgttgagttt attgaaaaac cggacgagcc gcagaccctg
    14581 gactccgatc tgatggcggt ggggcgctat gtgctgtcgg cggatatctg ggccgaactg
    14641 gaacgtaccg agccgggtgc ctggggccgt atccagctga ccgacgccat tgccgaactg
    14701 gcgaagaagc agtccgttga cgcgatgctg atgactggcg aaagctatga ctgcggtaag
    14761 aaaatgggct atatgcaggc cttcgtcacc tacggaatgc gtaacctgaa agagggcgcc
    14821 aaattccgcg aaagcattaa aaaactgctg gcctgaacgc cagcctgaga ccgagcgaca
    14881 ggatctgaac atccgtcctg ccgctcataa cgttatgcaa aatttattca taacgtaaat
    14941 gttatatcga ttgtaaagaa atgtatggct tcggagactt ctggtagttt gtctctggca
    15001 tctgtggtgc aatagtcgga gtagtggcaa taatgcttta tgaatagtca cttagtgcga
    15061 caattcctaa agtgcatgga aagcggtcaa cgtcagccaa aaataaaact tgactgcgat
    15121 catgtttccg ctttaaacat ctcacttgca tgcataaaaa tgtgaaatga attggcatgc
    15181 gacctggtat agacattacg gataatccct gagcacggca gtggacatta tcgaaggatc
    15241 acaggtatat gaactggcaa ctcatctcat tttttggcga tagcaccgtt ttgctgccca
    15301 actcagcggc gctgtttatt gtcctgatgc tgtgtaaaac gtcgcggttg ctggcgtggc
    15361 agtgaagttt gctgttcggc attgccggcg ttatcgtctg cgcccccaaa ctggccttta
    15421 tgggctgggg catttgtgag ctggattaca ccggcttcag cggccttctg gcctatcttc
    15481 ctgtggctac tcagatcccg tttctccgtc ggtctgcata aagcggccat tattaccgtc
    15541 catgttctgg ccgctgtggt gggctattcg cggctggtca tccatgtgca ttccgtctcg
    15601 gaagtggttg ccggcccgct gctggcaacg ctttgttcct gctgctgcaa aaacgtacct
    15661 ctgatccgga aagcgtgaat atctcatggg gcggtgtcgc ttgcctggtg atggttccgc
    15721 ttatcctgct acatagcggc agcaaagcac caactcagtc cctgcgggga caaatcgcca
    15781 ccgcggtggg gccgctggat aaccctttac gcgtaccgat ctgcacaagc atgcttggta
    15841 attgccattt gttttacagg ggaaattaag ttttcgccgg ttaattagac aaataagaaa
    15901 ataatctact atatactcgg taattgataa ttcatattta tgaaataatg ggtggtggct
    15961 ccaacttact gatagtgttt gatgttcaga taatgcccga tgaccttttc atgcagttcc
    16021 accgattttg agaacgacag tgacttcctt cccagccggg ccagatgctg cctcagattc
    16081 aggttatgcc gctcaatgcg ctgcgtgtaa cgcttgctga taacgtgcag cctctcctta
    16141 agccgtgact catacagcga ccatccgtcc gtcatccata tcacgacttc aaagactgac
    16201 aacaggctca gaagacgctc cagcgtggtc atagtgcgtt ctctgaatac atgggccaca
    16261 actgtcctgc gcatcctgtc atacgcgtaa aacagccagc tctgggggga tttagcgccg
    16321 acgtagcccc actgttcgtc catttccgcg cagacaatga cgtcactgcc cggttgtatg
    16381 cgcgaggtta ccgactgcgg cctgagtttt ttaagtgccg taaaatcgtg ttgaggccaa
    16441 cgcccataat gcatgcactg gcgcgacatc cgacgccatt catggccata tcaataattt
    16501 tctggtgtgt accgggcaga gaggcggtgt aagtgaactg cagttgccat gttttacggc
    16561 aatgagagca gcgatagcgc tgatgtcggg cagtgctttt gccgttacgc accacgcctt
    16621 cagtagctga acaggaagga cagctgatgg aaatggaagc cactggagca cctcaaaaaa
    16681 aacatcatac actaaatcag taagttggga gcaccgatat tcggtaacaa cactcccaat
    16741 tgtgaccgaa attctgtaaa cttagtgccg ccaaaaataa tggcctgacc aattattcat
    16801 ccacaggtcg ataaaaatta agtcgttcag gtagtcagtg cgctggtagc tgttaagcca
    16861 ggggcggtag cgtcgctgaa gccgcttgct gctgcacaga ggttctcttc aacggctgta
    16921 aatatcgacc cggtcaggat gatcattatc aatagatatc tatcaatttt ctacggatat
    16981 cctcagaagt tggccaggag cggctgctga tatcgcctgg acattaactt tcctgtctca
    17041 tcgatagcct gtagggtaaa attcgcctac attgtgagca gagtggatgt tataaggcta
    17101 acaagcagct tagggtaaat gtacttgcct cgccggtgtt gcacagcgaa gtcagctggt
    17161 gccgcgagcg ctttctatct tggtattccc ctcattctca ttgagatacg acagcggggc
    17221 tgaaaatgga tcttgtacaa tgataaaaat tgcgcgcatt gccgtgacgt tgggtttgtt
    17281 ttcctccctg ggagcccagg cttacgcggc cgggttagtg gtaaatgaca acgacttgcg
    17341 taacgacctg gcctggcttt ccgatcgcgg ggtcatccat ctgagcctgt cgacgtggcc
    17401 gctgagccag gaagagatcg cccgggcgct gaaaaaggcc aaaccttcct attcttctga
    17461 gcaagtggtg ctggcccgta tcaaccagcg attgtctgct ttaaaagccg atttcctggt
    17521 tatcggctac acttcaaccg accagccggg caccccgcag gggtttggtc agacacagcc
    17581 agcggataac tcgttaggcc tggcattcaa caacagtggc gagtggtggg acatacacct
    17641 ccagggtaac gttgaagggg gagagcggat cagcaacggg tctcgcttta acgccaatgg
    17701 cgcctatggc gcggtgaagt tctggaacca gtggctctcc tttggccagg ttccgcagtg
    17761 gtgggggcct ggttatgaag gcagcctgat ccgcggggat gcaatgcggc cgatgaccgg
    17821 ctttttaatg cagcgtgccg agcaggcggc accggaaacc tggtggctgc gctgggtggg
    17881 tccatggcag tatcagatct ccgccagcca gatgaatcaa tatactgctg tgccccatgc
    17941 caaaattatc ggcggacgct tcacatttac accgtttcag tcattagaat taggcgcatc
    18001 gcgtattatg cagtggggag gggaagggcg ccctgaatcg ttcagcagtt tctgggacgg
    18061 ctttaccggg aaagacaaca cagggacgga taacgaaccg gggaaccagc tggccgggtt
    18121 tgattttaaa ttcaaactcg agccgacctt gggttggccg gtgagtttct acggccagat
    18181 gatcggtgag gatgaatcag gttacctgcc atcggccaac atgttcctgg gtggggtcga
    18241 agggcaccac ggctggggta aggatgcggt taactggtat gtggaagcgc atgatacgcg
    18301 tactaatatg agccggacca attacagcta taaccatcac atctataaag atggttatta
    18361 ccaacaaggg tatccactgg gcgatgcgat gggcggggat ggtcaactca ttgccggtaa
    18421 ggttgagctt attacggagg ataaccagcg ctggagtacg cgcttagtat acgcgaaggt
    18481 taacccggag aatcagtcga tcaacaaagc gttccctcat gcggatactc taaaaggtgt
    18541 acagctgggc tggagcggcg atgtttatca gtcggttcgt ctgaatacct ccctgtggta
    18601 caccaacgct aacaacagcg acagcgatga cgttggggcc agcgctggga tagaaatacc
    18661 gtttagttta taaggctgaa tgctgaaaac aggggagata gggtggtagc gctgcaggac
    18721 gcagtcagct tttctctctc cataagccgg cagggaagca acggctatga cagctgctca
    18781 ggaattggca aattttgatt tactgatgat gtgacattat gaagaaaaaa cttgttagat
    18841 tttcggcatt agcgttggca attgggtttt tatcgggttg tacggttata ccaggtcaag
    18901 ggttaaatac tctgcgtaag aatgtggttg aactaccaga cagcgattac gatctggata
    18961 agctggttaa tgtttatcct atgaccccag gactgatcga acagctccgt cctgaaaccg
    19021 tgctggctcg tcccaacccg cagctggata atttgctgcg cagttacgaa tatcgcattg
    19081 gggttggtga cgtactgatg gttacggtat gggatcaccc ggaattgact actcctgctg
    19141 ggcaataccg cagcgccagc gacacaggta actgggtaaa ctccgatggc accatttttt
    19201 atccatatat cggtaaggtg caggtggcag gcaaaacatt aagccaggta cgccaggata
    19261 tagcaagtcg tttgaccact tatattgaaa gcccgcaggt tgatgtaagc gtagctgcgt
    19321 tccgttcaca aaaggcctat gtgactggag aagttgaaaa atcaggccag cagccaatca
    19381 ctaatatccc tttaacagtt atggatgcga taaacgctgc cgggggacta tccgaaaacg
    19441 ctgactggcg taatgttgtg ctgacacata atggtaaaga tactaaaatc tcactctatg
    19501 ctctaatgca aaaaggggat ttaaccgaga accggttgct atatccagga gatattctat
    19561 ttgttccacg gaatgacgac ttaaaagtat tcgttatggg tgaggtgggc aaacaaagca
    19621 caatgaagat ggatcgcagt ggcatgacgc ttgcagaggc actgggtaat gctgaaggta
    19681 tgtctcaagc cttcagcgat gctacaggtg tttttgttat tcgccaattg aaaggtgata
    19741 agcaaggtaa aatagcaaat gtttatcaat tgaatgctca ggatgcttcg gcaatggtgc
    19801 tcggcactga atttcagcta caaccctatg acattgtgta tgtgacgact gcgccacttg
    19861 ttcgctggaa cagggtcatt tctcagttgg taccaacgat cagtggcgtc catgacatga
    19921 ctgaaaccgt taagtttgtc aaggatatgc aataatgttt gattctattc ttgtcgtttg
    19981 tacgggaaat atatgtcgtt ctccaattgg ggaacgtttt ttacagaaag ccttgcctac
    20041 aaagaaaatt gattctgcag ggactaatgc attgataggc cataaagctg atgatagtgc
    20101 aattaagatt gcggaaaaac atggtatttc attagcggaa catgtaggac gtcagtttac
    20161 ttcttttatt ggtcgacaat atgatctgat tttagtaatg gaaagatatc atattgaaaa
    20221 aattggacag attgccccag agttgagagg taaaacaatg ctttttggcc aatggcttaa
    20281 ccaaaaagaa attcctgatc catatcgcaa aagtgatgaa gcatttgcat ctgtatatca
    20341 gttaatcgag ttagctggct tacgttgggt tgagaaatta ggcgcataat aactatcagg
    20401 aaaattgtat gtcatcagta aaaaatagaa ctgttgagaa agaggcagat gagatcgatt
    20461 taggtcgttt agttggagag cttatcgatc atagaaaact cattatttcg gttacggcgt
    20521 tatttacttt aatcgctctg ctttatgcac tctttgcaac gcctatttat caggctgatg
    20581 cgttactaca agtagagcaa aagcaaggta atgctattct gaatagtcta agccaaatgt
    20641 tacctgacag tcagcctcaa tctgcaccag aaattgcatt gttgcaatct cgtatgattc
    20701 tgggaaaaac tgtagatgat ctaaatttac aagctaagat cgaacaaagt tattttccgt
    20761 tattaggtaa aggatgggct cgtttggtag gagaaaaaaa agggatttta gttgttagcc
    20821 gactctattt gtcatctgat agcaacacag aaataccaaa attaaaactg aaggtaaagg
    20881 acgcgaacaa ctatattgtt acttttaatg atcacgagtt cgaaggcaaa gtcggggttt
    20941 tgctcgattc aaatggcatt tcgcttaaag ttgatagtat tgaggctaaa cctggaactg
    21001 agtttgttat atcttatgtt agtaagctgc aagctataac tgacttacaa gaaatttttt
    21061 cagtagcaga tcaaggaaaa gatactggaa tattaagcct atctttaact ggcccagatc
    21121 cacttttgct agagaaaacg ctaaacagca tcagtaataa ttatcttgca caaaatgtag
    21181 cgcgccaagc agcacaggat gctaaaagtc tagagttttt aaaccaacaa ctgcctaaag
    21241 tacgcaatga tttagatatt gctgaagata agctaaatca atatcggcgt caaaaagatt
    21301 ctgtagatct ttcgttagaa gccaaatcag tacttgaaca aatagttaat gtcgataatc
    21361 agcttaatga attgacattc cgtgaatcag aaatctcgca gctttatact aaagaacatc
    21421 cgacctataa ggcgcttatg gaaaagcgta aaactttgca ggatgagaaa gcaaagctta
    21481 atgaacgtgt ttcagcaatg ccgaaaacac agcaagatat cttacagtta agcagagatg
    21541 tagattctgg gcaagctgtt tacatgcagc ttcttaatcg tcaacaggaa ctcaatattg
    21601 caaaatctag cgctattggc aatgttagaa ttattgatga tgctgtttcc caaccggaac
    21661 cagtaaaacc gaagaaaata ataattgtac ttgttgggat tgttctggga ggtatggtat
    21721 ctataggcat agtattgtta aggatcttct tgcgtcgagg gatcgaaagt cccgagcaac
    21781 ttgaagaact tggaattaac gtttatgcga gtatacctat ttctgagact tttgctaata
    21841 aggctcttca aaatacaaaa ttgagaagaa aagcaggcag tgaataccag agctttttag
    21901 cggttgataa ccctgcggat ttggcaatag aagctatccg cggtttgcgt acaagcctgc
    21961 acttcgcaat gatggaagca cgaaacaatg tcttgatgat ttctggagct agccctaatg
    22021 tcgggaagac ttttgttagc tctaatcttg ctgcaataat tgctcaaact ggaaaaaaag
    22081 tactttttat agacaccgat atgagaaagg gttataccca caagttgttc aatttgagta
    22141 atgataatgg actttcagat gtattgtcgg gaaaaattga agtaagtaaa gcaattaaaa
    22201 aagtatcttc tgcaggcttt gattatattt cacgaggtat ggtcccacct aatccagcag
    22261 aattattaat gcatcgtaga ttaggtgagc taataacgtt ggttagtcaa agttatgaca
    22321 tcgttatatt agatacgcca ccaatactag cggttacaga tgctgctatt attgggaatt
    22381 atgttggaac aacattattg atagcccgat ttgaacaaaa tacgacaaaa gaaattgaag
    22441 ttagttttaa gcgttttgaa cagagcggtg tcattgttaa aggttgtata ctaaatggtg
    22501 tagtgaaaaa agccagtagt tattatagct atggctatag
//
LOCUS       DAPOAV010000074        22524 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.074, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000074 DAPOAV010000000
VERSION     DAPOAV010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22524
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.074"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..520)
                     /locus_tag="RN951_003221"
     CDS             complement(<1..520)
                     /locus_tag="RN951_003221"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528182.1"
                     /translation="MVNLTKNGVEFYWSRNGSRGGGIGENIVTAIGVFKVNVKAEINI
                     TPSMRTFSLISSLDPDFQASVSLSGFEKIYYNYGDSYKDIQDELQALLDANNRYKWDS
                     AHEMGHKVLDEYGEGSSPDYSWTHKGTSTLMQKTIPGNVMPAQGEIDVMKYGKYRPDM
                     YTRLVAADEDVQG"
     gene            complement(644..901)
                     /locus_tag="RN951_003222"
     CDS             complement(644..901)
                     /locus_tag="RN951_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014640299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528183.1"
                     /translation="MTNKGDEAEGLSLEVLDGNEVIYSEQQTGKYFDKGEHAWQWDGY
                     SNQGILDTTKLKSKSLLVRLIALCGDMMIKVDYPLHNSPEE"
     gene            complement(914..2091)
                     /locus_tag="RN951_003223"
     CDS             complement(join(914..1833,1833..2091))
                     /locus_tag="RN951_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611881.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDX2528184.1"
                     /translation="MNKKTKRTFTPEFRLECAQLIVDKGYSYRQASEAMNVGSTTLES
                     WVRQLRRERQGITPSATPITPDQQRIRELEKQVRRLEEQNTIFKKGYRALNVRLAERF
                     TIAARLSDSHTVVSLCSALEIHRSSYRYWRKRRDTVNPARVRLCSEIRRAWNQSRGSA
                     GARTLAEMLTQNGVPMSRYRAGRLMKYLNLSSCQPGKHQYKNARQEHTSLPNLLERQF
                     AVPEPDRVWCGDITYLWAGNRWCYLAVVMDLFARRVIGWSLSAHADTALISSALRMAY
                     ETRGQPRDVVFHSDQGSQYTGLKYQQLLWRCRINQSVSRRGNCWDNSPMERFFRSLKT
                     EWVPTNGYAGKDEARQQINDYILNYYNSVRPHHYNGGLTPEESENRYHFYCKTVANIT
                     "
     gene            complement(2148..3101)
                     /locus_tag="RN951_003224"
     CDS             complement(2148..3101)
                     /locus_tag="RN951_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001348788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528185.1"
                     /translation="MPVRLNTIPDAESYPAPPARIKWLSALLLMLSVGVAITSLFASD
                     ELAKNGPHFWGLACGVPAFIWSLVASVRWLFFITQYIRADAWNKRREEVILQETRRGR
                     RALQILSFSVQTALNGDSVAETTAAFLARQQVLNTYVDLRGEDTVRRSVIPVLTNKPV
                     TGRLSEIISRLFIDIRPQLFLLPPDFHINVLLEIDAPLSGASVRTIWQDEWQKAGLPE
                     ARLFSAPEPGLAAVDDWLDNFIQEKTVLLVISVYLEPKTPERTAESSTALLLANRLTQ
                     TALTPLALLHRPERITDTEMMASGIAQALDWMPVQPDVVAH"
     gene            complement(3179..3661)
                     /locus_tag="RN951_003225"
     CDS             complement(3179..3661)
                     /locus_tag="RN951_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000845156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528186.1"
                     /translation="MKTCQLKKNESVQLLSLRTIDGDTLYLKFRNVITGAFLDTPTKS
                     YDFFGDVVLSQCINGSLIFALEYGSPYIKGCLVTGWENGFKGKNSPEGFCFAERNIPE
                     AVWFGKNNILIIIRNQMDVGTWKGKYIIYDNAKKSGERAYSSDNLPSKDGYIIFALNK
                     "
     gene            complement(3732..4334)
                     /locus_tag="RN951_003226"
     CDS             complement(3732..4334)
                     /locus_tag="RN951_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HDX2528187.1"
                     /translation="MADKSEKKKETTNKSAKKTLTKKSEKLTPAKDTAPKQVNVDPAI
                     RLKQIRQLVRNNNKSIMGEDYIICQIYKESRFKQFAGKNKHNAKGLMQMQRNAVRQVF
                     KYRQQKIKGRMTTDKETNEAFANADTFYKSDKIFDEKENIKIGTEYLQYWIDKEATIE
                     EAYRAYRGTDEAYYSVIKPCAEKLAKDPDNIQILMEGIGR"
     gene            complement(4356..6869)
                     /gene="vgrG"
                     /locus_tag="RN951_003227"
     CDS             complement(4356..6869)
                     /gene="vgrG"
                     /locus_tag="RN951_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HDX2528188.1"
                     /translation="MVTPTLNFDHSHHKLKIRGLQSPVDVLTFEGREQLSTPFRYDIQ
                     FTSTDKAITPELVLMQDGAFSLTAPPVQGMPVQTALRTLHGVITGFKHLSSSQDEARY
                     EVRLEPRMALLARSRQNAIYQNQTVPQIVEKILRERHQMRGQDFVFNLKSEYPSREQV
                     MQYGEDDLTFISRLLSEVGIWFRFATDARLKIEVVEFYDDQSGYERGLTLPLRHPSGL
                     FDGETEAVWGLNTAYSVVEKSVTTRDYNYRTATAEMMTEQHDATGGDNTTYGEAYHYA
                     DNFLQKGDKEAAESGAFYARIRHERYLNEQAILQGQSTSSLLMPGLEIRVQGDDAPAV
                     FRKGVLITGVTASAARDRSYELTFTAIPYSERYGYRPALIPRPVMAGTLPARVTSTVK
                     NDIYAHIDKDGRYRVNLDFDRDTWKPGYESLWVRQSRPYAGDTYGLHLPLLAGTEVSI
                     AFEEGNPDRPYIAGVKHDSAHTDHVTIQNYKRNVLRTPANNKIRLDDERGKEHIKVST
                     EYGGKSQLNLGHLVDAGKQQRGEGFELRTDMWGAVRAKKGIFISADAQDKAQGQVREM
                     APAMAILDGAQSQMQSLSTDAQTTNADPADLSSQIALLQQSVKDLTQAVILLSAPKGV
                     AIASGEHLQLAASKNVIANAGNNADIGVVKNMFIGVGQALSVFVRKAGIKLFANKGAV
                     SVQAQNDLMELLAQKSIEITSTEDEIKITAKKKITLNGGGSYIRLDACGIEAGTPGEY
                     NVKAGYYGRKPKAKLTPELMAFPVIKSEDFNQSFILLDENTGQPLINWPYELELESGL
                     KMSGITDENGNTELISSDKEEVVNISVFEPDEFLDDDIN"
     gene            complement(6923..7411)
                     /locus_tag="RN951_003228"
     CDS             complement(6923..7411)
                     /locus_tag="RN951_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001535538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528189.1"
                     /translation="MILKTISRLFFFIIVAVYFLMFILSLDGGGRLSTLNILAAIGGN
                     TFWCMLVVISLAGSAGICVYMLKKNCLTNSAVTILSTSFIFTTSIFIILFLKAEFVLD
                     WLYCIYIEIFFNGDFYSGQERVLQTVPFMIRTYFLFLMANLFLFWLSFFFLIKNKTLH
                     KA"
     gene            complement(7468..9417)
                     /locus_tag="RN951_003229"
     CDS             complement(7468..9417)
                     /locus_tag="RN951_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2235 domain-containing protein"
                     /protein_id="HDX2528190.1"
                     /translation="MWGMLDTGGGIRAQLAEDNKVGNCGREWHVGFFFDGVGRNIDQD
                     ASEQRLSNVARLFRAYPDEDFNTDFVCHNKFYFSGMGTPYNEELISKLYTIMDQSLES
                     MKEDLNDFAKETHEEISKEIRNRRGSWNETLKKIQDKLLDPKELRKKRNDIFKNMAKK
                     SIIESTQWIRDNEIISAFFLTGEVTRINAAKVLFANAFVENSTNKKDSTAIKIKSISV
                     SLYGYDTGAALARKFLDELLEEFCEKEGEDKYLFKKVPVNIVFAGFFDCSRHSPASNN
                     NGLDYFLSLPGKITKNNKLKTAGKIAKVAFGEKAIELDTILPGTVKNALHLVAAYERR
                     LWRSLYQLGSSNTEHKEILLPGCSEDVGGGLKPDEQKPSAELCRVALQKMYEAAYDAG
                     VPFPDFETLPSFSETVSRYFLMNEAVEGKSVKEWMKSYDMEVGQCQKETQSASESKVN
                     DTDNKNDLPFDFYLDIYFKWLANQYYLYCTELYQLDEKLSLAHRKQISGYGPLAGTGI
                     NPNPEADEINAQIAELKSHWGWLDDVRRVATGLSNDFNYGRPMDTRMLNHEDIFRPAW
                     KRAELFLDYYHKAWNGEELTDISWLGIDTIHSYFTHDLQTVDTGASINESFFLRRMAE
                     YPKSKEKPEEKSEEQSPSPDLSGGD"
     gene            complement(9458..10012)
                     /locus_tag="RN951_003230"
     CDS             complement(9458..10012)
                     /locus_tag="RN951_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3304 domain-containing protein"
                     /protein_id="HDX2528191.1"
                     /translation="MGLFTRLEKFDQKLTRGYARWGHWVWRMLIAVPVLVVLWNIGQA
                     VWGGPRGGVILEIHSEIDRPILGFSVNGVAGANAFANGGGSTTCCGDVSGDTAEVIWT
                     LDMTHEQYLKGMRLEKRNKTLPLPKREWGENYLHVHFMPGDKVLLGWSKDSFSPYEDL
                     HNGGYKTRVRQDVKDKLYGTGKMN"
     gene            complement(10056..10876)
                     /locus_tag="RN951_003231"
                     /pseudo
     CDS             complement(10056..10876)
                     /locus_tag="RN951_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200148.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4123 domain-containing protein"
     gene            complement(10879..13251)
                     /gene="vgrG"
                     /locus_tag="RN951_003232"
     CDS             complement(10879..13251)
                     /gene="vgrG"
                     /locus_tag="RN951_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001724923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HDX2528192.1"
                     /translation="MGIQNFDHSHHKLKIRGLQSPVDVLTFTGREQLSASFRYDIEFT
                     STDKAITPESVLMQDGALSLTAPPVQGMPVQAPLRTLYGVITGFKHLSSSQDEARYEV
                     RLEPRMALLTRSRQNAIYQNLTVPQIVEKILRERHQMRGQDFVFNLKSEYPAREQVMQ
                     YGEDDLTFVSRLLSEVGIWFRFATDARLKIEVIEFYDDQSGYERGLTLPLRHPSGLFD
                     GETEAVWGLNTAYSVVEKSVTTRDYNYRTATAEMMTEQHDATGGDNTTYGEAYHYADN
                     FLQKGDKEAAESGAFYARIRHERYLNEQAILKGQSTSSLLIPGLEIRVQGDDAPAVFR
                     KGVLITGVTASAARDRSYELTFTAIPYSERYGYRPALIPRPVMAGTLPARVTSTVKND
                     IYAHIDKDGRYRVNLDFDRDTWKPGYESLWVRQSRPYAGDTYGLHLPLLAGTEVSIAF
                     EEGNPDRPYIAGVKHDSAHTDHVTIQNYKRNVLRTPANNKIRLDDERGKEHIKVSTEY
                     GGKSQLNLGHLVDAGKEQRGEGFELRTDLWGAVRAKKGIFISADAQDKAQGQVREMAD
                     IISELNGLSDKIQKLSDDATTANADPADVAAQIALITSRINDLTASVILMHAPKGVAV
                     ASGEHLQLAAVKNLQINAGNNADIGVVKNMFIGVGRALSVFVRKAGIKLIANKGAVSV
                     QAQHDLMELLAKKSIEIVSTEDEIRISAKKKITINGGGSYIRIEGSGIEPGTPGDYNV
                     KAVHYGRQPKASEKVPMPEFPILSAVDSSDFCLECLLNAIKNDDAVVEGA"
     gene            complement(13263..15908)
                     /gene="tssH"
                     /locus_tag="RN951_003233"
     CDS             complement(13263..15908)
                     /gene="tssH"
                     /locus_tag="RN951_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001535533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system ATPase TssH"
                     /protein_id="HDX2528193.1"
                     /translation="MTGNHPAALLRRLNPYCARALDAAASLCQTRAHAEITIEHWLLK
                     LLEQGEGDITVIARRYEWDIDTLWQSLLAHLDTLPRSVRERPQLSEPLTALIRQAWLI
                     ASLEGDDPQIRSQHLLMALTEKPMLPACNDLWVLLSLSRVQLERLRPLLDAQSDECPA
                     RQPQVTEPLTSAQPEAATTDAPAKTLTGKQDDALLAVLNRFTEDVTEKARSGRIDPVF
                     GRDTEIRQMVDILSRRRKNNPILVGEPGVGKTALVEGLALRIAEGNVPDSLKTVHIRT
                     LDLGLLQAGAGVKGEFEQRLKNVIDAVQKSPEPVLLFIDEAHTIIGAGNQAGGADAAN
                     LLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKA
                     RYAQHHGVHMLDSAIQTAVRLSRRYLTGRQLPDKAVDLLDTAGARVRMSLDTLPEPLT
                     QLQARLTALDIEREAIEQDSVFYPETSPERLAELTDLRDELQAEAGHLEAQYQQEKRL
                     AQQIMALRQEGADSTDLQQQLRTHQGFAPLLALDVDARAVATVVADWTGIPLSSLLRD
                     EQSDLLSMEQSLENRVVGQSPALCAIAQRLRAAKTGLTPENGPQGVFLLTGPSGTGKT
                     ETALTLADTLFGGEKSLITINLSEYQEPHTVSQLKGSPPGYVGYGQGGVLTEAVRKRP
                     YSVVLLDEVEKAHRDVMNLFYQVFDRGFMRDGEGREIDFRNTVILMTANLGSDHIMQL
                     LEEKPDATDADLHELLYPLLRDHFQPALMARFQTVIYRPLGQEAMRTIVEMKLAQVVR
                     RLRQHYGLETEINDSLYDALTAACLLPDTGARNIDSLLNQQILPVLSQQLLAQQAAHR
                     KPAQLQLGWDEEDGIVLEFTTEEMQ"
     gene            complement(16099..16590)
                     /locus_tag="RN951_003234"
     CDS             complement(16099..16590)
                     /locus_tag="RN951_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hcp family type VI secretion system effector"
                     /protein_id="HDX2528194.1"
                     /translation="MAIPAYLWLKDDGGADIKGSVDVQGREGSIEVVALDHDVYIPTD
                     NNTGKLTGTRTHKPFIFTKEIDASSPYLYKAVTTGQTLKTAEFKFYRINDAGQEVEYF
                     NITLDNVKLVRVAPLMHDIKEPSKEKHNHLERIEFRYEKITWTYKDGNIIHSDSWNER
                     PSA"
     gene            complement(16648..18300)
                     /locus_tag="RN951_003235"
     CDS             complement(16648..18300)
                     /locus_tag="RN951_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDX2528195.1"
                     /translation="MRNTLKQAVVLWGMVLLLVLWSVFISPSGVLRWAGAAAIVLAVA
                     ALLIYRRRQAWTEMTGDAGLSSLPPETYRQPVVLVCGDMSAHLFTDSPVRQVSEGLYL
                     HVPDEEQLVAQVERLLTLRPAWASQLAVAYTVMPGMYRDAAVLTGRLRRFAHSMATVR
                     RRAGVNVPWLLWSGLSGSPLPERANSPWFICTGGEIHVATSAETASPAQWLTQTSTQE
                     RSQQLCYLLKAESLMQWLNLNMLAALNGPETKCPPLAMAVGLVPSLPAVDNNLWQLWI
                     TARTGLTTDIADTGTDATLPFPDALLRRLPRQSGFTPLRRACVTMLGITTVAGIAALC
                     LSATENRQLLRHIGDDLHQFYAVPAEEFITKARRLSVLKDDAIMLDGYYREGEPLRLG
                     LGLYPGEQIRQPVLRAIRDWRPPEQKMEVTASLQAQTVRLDSMSLFDVGQARLKDGST
                     KVLVDALVNIRAKPGWLILVAGYTDATGDEKSNQQLSLRRAEAVRNWMLQTSDIPATC
                     FAVQGLGESQPAATNDTPQGRAVNRRVEISLVPRSDACQDVK"
     gene            complement(18313..18978)
                     /gene="tssL"
                     /locus_tag="RN951_003236"
     CDS             complement(18313..18978)
                     /gene="tssL"
                     /locus_tag="RN951_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein TssL, short
                     form"
                     /protein_id="HDX2528196.1"
                     /translation="MKKETDINIDALLRDTFLTVVELRQGTTVRHGMELYRHCQRQVE
                     GVRERLKDAGFSRESVEHITYAQCALLDETVLSRSGMDDGQAIWMKDPLQSHFFNTLQ
                     AGELLYERMKQVLQEPAPAQAVLTCFHRVLLLGFRGRYQDPVAPERDQLISTLNGLVA
                     PFGVLPETAVLNVPLSTRQHPLLHSPFFWLVTLTLLLAGVWWGLHHWLNVLVDELLPQ
                     SLR"
     gene            complement(18975..20312)
                     /gene="tssK"
                     /locus_tag="RN951_003237"
     CDS             complement(18975..20312)
                     /gene="tssK"
                     /locus_tag="RN951_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssK"
                     /protein_id="HDX2528197.1"
                     /translation="MKIHRPLWAEGTFLSSQQFQQQARWEAFSNDSIAQLCIRHPWGI
                     ANVLFDRDALMSGKLKTQAVRLRFADGTLIDSDVSDVLPLACDLHALTNDSAVVLLAL
                     PLAHGNGGNLGQGEQTERPLRYRQEWQKVQDIYGSDSEDMAVERHALSLRFAHDNNQD
                     YITCPLARLVRDVQGNWTQDEGYIPPLLAFNAHDGLVQRLDTLLLQLRAKCQRLMAMR
                     RESNQRMADFAVADVSLFWLLNALNSAEPVLSDFLRYPAVHPELVWRELARLAGALLT
                     FSLEHNVSAVPPYVHESPSTVFPPLFSLLSELLEASLPSRVIALDLGSLPGNRWKADL
                     HDPRLREEADFYLSVRSSLPAHQVLHQLPLVCKIGAPDDVTLLINVALNGVPLVPLTS
                     VPAALPLRLENQYFALDMHSDAAKSMLESGCCMIYTPGTMGDLKPELFAVLRT"
     gene            complement(20330..21868)
                     /gene="tssC"
                     /locus_tag="RN951_003238"
     CDS             complement(20330..21868)
                     /gene="tssC"
                     /locus_tag="RN951_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001314091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     large subunit"
                     /protein_id="HDX2528198.1"
                     /translation="MSVQQEHATSETATLTTTESGGVYQSLFDKINLTPVSSIQEIDL
                     WQNSETLADASPDERVTAAIHVLLSCLAKSGENVVKLDKSLLDFHIDDLDQKISKQLD
                     AVMHHPEFQKVESLWRGTWFVVQRTDFRKNVRIELLDISKEHLRQDFDDSPEIIQSGL
                     YRHTYIQEYDTPGGEPVASLISSYEFDNSPQDIALLRNISRVSAASHMPFIGSVGPKF
                     FLKNSMEEVAAIKDIGNYFDRAEYIKWKSFRDTDDSRYVGLVMPRVLGRLPYGPDTVP
                     VRSFNYVEEVKGPDHEKYLWTNASFAFAANMVKSFVNNGWCVQIRGPQAGGAVADLPI
                     HLYDLGTGNQVKIPSEVMIPETREFEFSNLGFIPLSYYKNRDYACFFSANSAQKPALY
                     DTADATANSRINARLPYIFLLSRIAHYLKIIQRENIGTTKDRRVLELELNTWIRTLVT
                     EMTDPGDELQASHPLRDGKVIVEDIEDNPGFFRVRLFAVPHFQIEGMDINLSLVSQMP
                     KAKA"
     gene            complement(21927..22427)
                     /gene="tssB"
                     /locus_tag="RN951_003239"
     CDS             complement(21927..22427)
                     /gene="tssB"
                     /locus_tag="RN951_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001557371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     small subunit"
                     /protein_id="HDX2528199.1"
                     /translation="MADSFQNEVPAARVNIKLDLHTGNAKKKVELPLKLLAVGDYSNG
                     KEQRPLSERDKIDINKNNFNSVMAEFSPAVNLTVEDTLSGSGNEQNIALEFKSLKDFE
                     PEQVAKNIPQLRVLLAMRNLLRDLKSNLLDNATFRRELENILKDPTLSSELRDELAKI
                     APQENV"
BASE COUNT         5015 a         6155 c         5474 g         5880 t
ORIGIN      
        1 atccctgaac atcttcatct gctgcaacca atcgagtata catgtcagga cgatattttc
       61 catatttcat tacatcaatc tctccctgag cgggcataac attccctggt attgtttttt
      121 gcataagagt agatgttcct ttatgagtcc acgaataatc agggctagaa ccctctccat
      181 attcatcgag tactttatgc cccatttcat gagcactatc ccatttatat ctgttattag
      241 cgtcaagaag cgcctgtaat tcatcttgaa tatccttata actatcaccg tagttataat
      301 atattttttc aaatcctgat agactaacgg atgcctgaaa gtcaggatct aatgatgata
      361 tcaaagaaaa agttcgcatg gatggagtaa tatttatctc agcctttaca tttactttaa
      421 aaacaccaat cgctgtaaca atattttcac caatcccccc gccgcgactt ccatttcgag
      481 accaataaaa ttcaactcca tttttggtca ggttaaccaa gtcgttataa ggaactgggg
      541 ataacttagg attacttcct tttatccctc catcactaac tgccagtcgc catattatat
      601 ctactgtttt ttgttttctg tctaccttta catcgaccca tttttattcc tctggtgaat
      661 tatgaagtgg ataatcaact tttatcatca tatcaccaca taaagcaatc agtcttacga
      721 gtagtgattt gctttttagc ttagttgtat ccagtatgcc ttgattactg tagccatccc
      781 attgccaggc atgctctccc ttatcaaaat atttaccggt ctgctgttca ctgtaaatca
      841 cttcattacc atcaagcact tccagagaaa gtccttcagc ctcatcgcct ttatttgtga
      901 tagtatgtag tggtcaagta atattggcca cggttttaca gtaaaaatgg tatctgttct
      961 ctgactcttc cggcgtcagc ccaccgttat aatggtgagg tctgacgctg ttgtagtagt
     1021 tcaatatgta atcattaatt tgctgccggg cctcgtcctt gcctgcgtaa ccattcgttg
     1081 gcacccattc tgttttcaga ctgcggaaga agcgttccat ggggctgtta tcccagcagt
     1141 ttccccgccg actgacgctt tgatttattc tgcaacgcca gagaagttgt tgatatttaa
     1201 ggcctgtata ctggcttccc tggtcgctat ggaacacgac atcccggggt tggccacgcg
     1261 tctcataggc catccgcagg gcactgctta tcagtgcggt atcggcatgc gctgacagac
     1321 tccagccgat aaccctgcgg gcaaaaagat ccataacaac cgccagatag caccagcgat
     1381 ttcctgccca gagatacgta atatctccac accatacccg gtctggctcc ggtactgcga
     1441 actgacgctc aagcagattc ggcaggctgg tatgctcctg acgggcattt ttatactgat
     1501 gttttccggg ctgacaactg ctcaggttca gatatttcat cagacgtccg gcacggtaac
     1561 ggctcatcgg gacgccgttt tgagtcagca tttcagccag agtgcgcgcg cccgcagagc
     1621 cccgactttg gttccacgcc cggcgtattt cgctgcacaa cctgactcgt gccggattaa
     1681 ccgtatcgcg tcgttttcgc cagtaccggt aactgctgcg gtgtatttcc agagcagaac
     1741 acaggctgac aaccgtgtgg ctgtcactta gtctggcggc tatcgtgaac cgttcagcga
     1801 gtcggacatt aagagcgcgg tagccttttt taatatcgta ttttgttcct ccagacggcg
     1861 aacttgcttt tccagctcgc ggatacgttg ctggtctgga gtaatgggtg tggcagaggg
     1921 cgtaataccc tggcgctctc gcctgagctg gcgtacccag ctctcaagcg tggttgaacc
     1981 gacattcatc gcttcactgg cctgtcgata tgagtagccc ttatcaacaa tcagctgtgc
     2041 acattccagc ctgaactcag gggtgaaggt tcgtttggtt ttcttgttca ttaagtcacc
     2101 tgttttgtgt tgtggtgaga atatcacctt tcatcaggtg gccaaattta gtgtgccact
     2161 acatctggct gcaccggcat ccagtccagc gcctgtgcaa tgcctgacgc catcatctct
     2221 gtatctgtga tacgttcagg acgatgcagc agggccagcg gcgtcagcgc ggtttgcgtc
     2281 aaccggtttg ccagcaacag cgcggtggag gattctgccg tccgttccgg agtcttcggt
     2341 tccagataca cggaaatcac cagcagtacg gtcttttcct gaataaagtt gtccagccag
     2401 tcgtccacgg cggccagccc cggctccggg gcagaaaaca gacgggcttc cgggagtccg
     2461 gctttttgcc attcgtcctg ccagatagtt ctcacggagg cccctgaaag cggcgcatca
     2521 atttccagta gtacgttgat atgaaaatca gggggcagca gaaacaattg cggtctgata
     2581 tcaataaaaa ggcgggaaat aatttcggat aaacgcccgg taaccggttt attggttaat
     2641 acgggaatga cactgcgacg cacggtatct tctccgcgca aatcaacgta agtattcaac
     2701 acctgctgac gcgccagaaa cgccgctgtg gtttctgcga cggaatcacc attcagcgcg
     2761 gtttgtacgg aaaaactaag tatctgcaac gcccgtcgtc cccgtcgcgt ttcctgcaaa
     2821 atcacctctt cccggcgctt attccaggca tcagcccgaa tgtactgcgt gataaaaaac
     2881 aaccagcgaa ctgaagcaac cagcgaccag ataaaggcag gcacaccgca ggccagcccc
     2941 cagaaatgcg ggccgttttt tgccagttca tcgctggcga ataatgaggt tattgccaca
     3001 ccaacagaca gcatcagtaa taaggctgac agccatttaa tgcgggctgg cggtgcggga
     3061 taggattctg cgtcgggaat ggtattaagt cggacaggca tcagtacatc cctttatttt
     3121 gcattatcgg ccagaagtta ataaccaagt gaaatttaaa gttatctata gagtcatttt
     3181 atttatttaa tgcaaaaatt atgtaaccat cttttgatgg tagattatct gatgagtatg
     3241 ctctttctcc tgactttttc gcattatcat agataatata tttccctttc catgtcccaa
     3301 catccatttg gtttcggatg ataattaaaa tattgttttt tccaaaccat accgcttcgg
     3361 gaatatttct ctctgcgaaa caaaagcctt caggagagtt cttaccttta aacccatttt
     3421 cccaaccagt taccagacaa ccttttatat atggagaacc atattccagc gcaaagataa
     3481 gagaaccatt tatgcactga gaaagaacca catctccaaa aaaatcataa cttttagttg
     3541 gagtatctaa aaaggccccg gtgataacat ttctgaattt tagatataat gtatcaccgt
     3601 caatggttct aagggaaagc aactgcacac tttcattttt tttcagttga caggttttca
     3661 cgattttaat cttatcgcct gaaaaacagg ggaaagaaaa aaaacaaagt aatattaaca
     3721 taatgcgcat actatcttcc tattccctcc attagtattt gtatgttatc aggatcttta
     3781 gccagttttt cagcgcaagg ttttataaca gaatagtatg cttcatctgt tccacgatat
     3841 gcccgatatg cctcctcaat tgttgcttct ttatctatcc agtattgcaa atactctgtg
     3901 ccaatcttaa tattttcttt ttcatcaaat attttatcag atttataaaa tgtatcagca
     3961 ttagcgaaag cttcatttgt ctctttatca gtcgtcattc ttccttttat tttttgttgt
     4021 cgatatttaa aaacctgcct cactgcattt cgttgcattt gcattaagcc tttcgcatta
     4081 tgtttattct tacctgcaaa ttgcttaaat ctagattctt tatagatttg acaaataata
     4141 taatcctctc ccatgatgga tttattatta ttacggacaa gttgacgaat ttgtttcaat
     4201 cttatagctg gatctacatt cacttgtttt ggtgcggtgt cttttgctgg agttaatttt
     4261 tcgctcttct tcgttagtgt tttttttgct gatttatttg tggtttcttt tttcttttcg
     4321 gatttatctg ccatgttata ttctcgctat atgtcttaat taatgtcatc gtctaaaaac
     4381 tcatcgggtt caaacacact aatattaacg acctcctcct tatcagagga tattagttct
     4441 gtatttccat tttcatcagt aatcccactc atttttagcc cactttccag ttctagttca
     4501 tagggccaat taataagtgg ttgcccagta ttttcatcca gcaaaataaa gctctgatta
     4561 aaatcctcag acttaatcac cggaaatgcc atcagctccg gcgtcagctt cgcctttggt
     4621 ttacgcccgt aatatccggc cttaacgtta tattctcccg gcgttcccgc ttctatcccg
     4681 caggcatcca gccggatgta gctgccaccg ccgttaaggg tgattttctt cttcgcggtg
     4741 atcttgatct catcttccgt actggtgatc tctatcgatt tctgtgccaa cagttccatc
     4801 agatcgttct gtgcctgtac cgagaccgcc cctttattgg caaacagctt gatgcccgct
     4861 ttacgcacaa acacgctcag cgcctgaccc acaccgataa acatattttt tactacgccg
     4921 atatctgcgt tgttgcctgc gttcgctatc acattcttcg acgccgccag ttgcaggtgc
     4981 tcgccgctgg cgatcgccac gcccttgggt gcacttagca ggatcacggc ctgcgtcaga
     5041 tcttttacac tttgctgcaa cagcgctatc tgcgatgaca gatctgccgg atcggcattc
     5101 gtcgtctgcg catcagtgga cagcgactgc atctgtgact gtgcgccatc cagtattgcc
     5161 atcgccggag ccatttcgcg cacctgcccc tgcgccttat cctgcgcatc ggcgctgata
     5221 aaaatccctt tcttcgcccg caccgcgccc cacatatcgg tacgcagttc aaagccttcc
     5281 ccgcgctgtt gttttccggc atccaccaga tgacccagat tcaactggct cttgccgccg
     5341 tactcggtac tgaccttgat atgctctttg ccgcgctcat catcgaggcg gattttgttg
     5401 ttcgccgggg tacgcagcac gttgcgcttg tagttctgga tggtcacatg gtcggtgtgc
     5461 gccgagtcgt gttttacgcc tgcgatataa ggtcggtccg ggttgccttc ctcaaacgcg
     5521 atgctgactt ccgttcccgc cagcagcggc agatgcaggc cgtaggtgtc tcccgcatac
     5581 gggcgcgact ggcgtaccca caggctctca taacccggtt tccacgtatc gcggtcaaaa
     5641 tcgaggttga cccggtagcg cccgtctttg tctatatggg cataaatatc gtttttcacc
     5701 gtgctggtga cccgcgccgg gagtgttccg gccattacgg ggcgggggat aagcgccggg
     5761 cgatagccgt agcgttctga gtagggtatc gccgtgaacg tcagttcata gctgcggtca
     5821 cgggccgcgc tggccgtcac gccggtaatc agcacgccct tgcggaatac cgcaggcgcg
     5881 tcgtcgccct gaaccctgat ttccagcccc ggcatcagca gtgaactggt gctctggccc
     5941 tgcagaatgg cctgttcatt caggtagcgt tcgtgacgga tacgggcata aaacgcgccg
     6001 ctttccgctg cctccttgtc gcctttttgc aggaagttgt cagcgtagtg gtaggcttcg
     6061 ccataggtgg tgttatcgcc cccggtggcg tcatgctgct ctgtcatcat ctctgctgtg
     6121 gcggtgcggt agttgtagtc ccgcgtggtg acgctttttt ccaccacgct gtatgcggtg
     6181 ttcagccccc atacggcttc cgtttcacca tcaaacagcc ctgaaggatg gcgaagcggc
     6241 agcgtcagtc cgcgctcata gccgctctgg tcgtcgtaaa actcgacaac ctcaattttc
     6301 agccgggcgt cggtggcaaa gcggaaccag atacccactt ccgacagcag gcgtgaaata
     6361 aacgtcaggt cgtcctcacc gtactgcatc acctgttcac gggacgggta ttcgcttttg
     6421 aggttaaaca cgaagtcctg accgcgcatc tggtgccgct cgcgcaggat tttttcgact
     6481 atttgcggca ccgtctggtt ctggtaaatg gcgttctggc ggctgcgggc cagcagcgcc
     6541 attcggggtt caaggcgcac ttcgtaacgg gcttcatcct gtgacgatga caggtgttta
     6601 aagccggtga tgacgccgtg cagggtgcgc agggcagtct gtaccggcat cccctgtacc
     6661 ggcggtgccg tcaggctgaa tgcgccgtcc tgcatcagca ccaactccgg cgtgatggct
     6721 ttatcggtac tggtaaactg aatgtcgtag cggaacgggg tactcagttg ttcgcgacct
     6781 tcgaaggtca gcacatccac cggactttgc aggccgcgaa ttttgagctt gtggtgcgag
     6841 tggtcgaaat taagagtagg agtaaccatt ttattttcct taatttattg gttagtactt
     6901 catatactta cctcatttga tactacgctt tgtgcaatgt tttattttta ataagaaaaa
     6961 agaaggatag ccagaataaa aaaagattag ccattagaaa aaggaaatat gttctaatca
     7021 taaacggaac tgtctgtaat actctttcct gacctgaata aaaatcccca ttaaaaaata
     7081 tctcaatata tatgcaatac aaccagtcca gtacaaactc tgccttaaga aaaaggatga
     7141 taaatatact tgttgtaaag ataaatgaag tagacaatat tgtcaccgca gaattagtca
     7201 ggcagttttt cttgagcata taaacgcata ttcctgcgct ccctgccagg gatatcacca
     7261 ccagcataca ccagaacgtg ttaccaccaa tggcggctaa tatattaaga gtactaagtc
     7321 gtccaccgcc atcaagagaa agtataaaca ttaaaaaata aactgctact ataataaaaa
     7381 agaataacct tgaaattgtt tttagtatca caaatacctc agattcatca tttaaattta
     7441 ttttattata gagagacatc acctgattta atcaccacct gacaaatctg gagatggtga
     7501 ctgttcttct gacttttctt ctggtttttc ttttgatttg ggatattcag ccatacgacg
     7561 aaggaaaaaa ctttcgttaa tagaagcccc ggtatcaaca gtttgtaaat catgagtaaa
     7621 ataagaatga atagtatcta tgcctagcca tgatatgtcc gtgagttctt ctccgttcca
     7681 tgctttatga taatagtcaa gaaacagttc agctcgcttc catgccgggc gaaaaatatc
     7741 ttcatgattt agcatgcggg tatccattgg ccttccgtaa ttaaaatcat tcgataatcc
     7801 tgtagcgaca cgccttacat catccagcca tccccagtga gatttaagtt ctgcgatctg
     7861 tgcattgatt tcatcagctt caggattagg gttaattccc gttccggcaa gagggccata
     7921 cccgcttatt tgtttgcgat gtgcaagtga tagtttttca tccaattgat aaagttcagt
     7981 gcagtaaaga tagtattgat ttgccaacca tttgaaatat atatcaagat aaaaatcaaa
     8041 gggcaggtca tttttattat ccgtatcatt tactttactt tcagaggcgc tttgagtttc
     8101 tttttggcac tgtcccactt ccatatcata gcttttcatc cactctttaa cggatttacc
     8161 ttctacggcc tcattcatga ggaaatagcg tgatacggtc tcagaaaacg atggtagcgt
     8221 ctcaaaatct ggaaaaggta ccccagcatc atatgctgct tcatacatct tttgcagggc
     8281 cacacgacat aactctgcgc tcggtttctg ttcatctggc ttcagaccac cgcccacatc
     8341 ctcgctacaa ccaggcagta aaatctcctt atgttctgta ttcgagctcc ccaactggta
     8401 aagactgcgc catagacgtc gctcataagc cgctaccaga tgtaacgcgt tcttaactgt
     8461 acctggtaaa atggtatcca gttcgatagc cttctcgcca aatgcgactt tggcgatttt
     8521 gccagctgtt ttcagcttat tattcttggt aattttcccc ggaagactta aaaaatagtc
     8581 cagcccatta ttattactgg ctggtgaatg acgtgaacag tcaaagaaac cagcaaagac
     8641 gatatttact ggtacctttt taaacaggta tttatcctca ccttcttttt cacaaaactc
     8701 ttcgagtaac tcatccagaa attttcgtgc cagtgcagct ccggtgtcat agccatacaa
     8761 cgaaacagat attgatttta ttttaatcgc agttgaatcc tttttattcg tactgttttc
     8821 aacaaaagca ttcgcaaaca acacctttgc tgcattaatt ctcgtgacct cccccgtcaa
     8881 gaaaaaagca ctaataattt cattgtcgcg gatccattgc gttgactcaa taatggattt
     8941 tttagccatg tttttaaaga tatcatttct tttttttcta agttctttag gatccagaag
     9001 tttatcctgg attttcttta aggtttcatt ccacgacccc cttctgttac ggatttcctt
     9061 gctgatttct tcatgtgtct cttttgcgaa atcgtttaaa tcctccttca tactttccag
     9121 agactgatcc atgattgtat ataattttga gatcaattct tcgttatagg gtgttcccat
     9181 accggaaaaa taaaatttat tgtgacaaac aaaatcagta ttgaaatctt catcaggata
     9241 agcccgaaat aaacgagcca cattacttaa gcgttgttct gaagcatcct gatcaatatt
     9301 gcgccccacg ccatcaaaga aaaaaccaac gtgccactcc cgcccacagt ttcctacttt
     9361 gttgtcttcc gcgagttgtg cccgaattcc accaccggta tctaacattc cccacattat
     9421 tacgtctcct gccgaacgtg atttttacag aaatctatca attcattttc cctgtgccat
     9481 aaagtttatc tttcacatcc tgccgaacgc gggtcttgta ccccccgttg tgaagatctt
     9541 catacggaga aaaagaatcc ttactccacc ccagcaacac tttatcgcca ggcataaaat
     9601 gcacgtgcag ataattttct ccccattctc tttttgggag aggcaaagtc ttgttacgtt
     9661 tctccagacg catcccttta agatattgct cgtgagtcat atctaatgtc cagataacct
     9721 ctgcggtatc cccactgaca tcaccacaac aggttgttga acctccacca ttcgcaaaag
     9781 cattcgcacc cgccacgccg ttaacactga atcccagtat cggacggtca atttcactgt
     9841 ggatttccag aatcactcca cctcttggac caccccatac tgcctgccct atattccaca
     9901 acacgaccag tactggcacg gcgatcagca tccgccacac ccagtgcccc cagcgggcat
     9961 aaccacgcgt aagcttttgg tcaaattttt ccagtcgggt aaatagcccc atcagatttt
    10021 attccctctt atcacctggt tggcaaagtt gtatgtcact ggcgactaag gtcagacaac
    10081 gaaatttcat ttcgtttcac cttttccagc atggcctgaa attcggctga ctcaagatac
    10141 gctttctttc cattcagata gctcaacgca taaattttct gatccagtgg ctttgtcagt
    10201 ccaaccgctt gtgccttatt caatgccttc tccaccatat ttcgctgaat acagggcggg
    10261 aagtgctcac tcgttttcat ggtgcgccac tctcttaaaa gcgcagatac atctccccga
    10321 tctgctattt tctgccagag cggttcatca agcgttatga tttccactgt ctcatcgctg
    10381 ttatttgccg caggaaacgg catgttcagc ctttgccacc gcgtatcttc cagcatccac
    10441 catgattctc tctgagagaa catcaccgga tgccactcca tatcgggccg ggcggccagt
    10501 tgtttcagca ctcggggcgt gtaatacctc agcagaactt cacgaccatc tggcgttttt
    10561 gccatgcacc ccacagcaag ccgggaggcc agttgctcca gcggcagctc tgaaaaaact
    10621 atgcctgcga cggggagttt cccgacaagc accatcgcca gatccttttc actttcaatg
    10681 caaaccaacc agggaccgta tgctgctacc tttttaaggt cggcagttga tacagggaaa
    10741 ttcgtcggta tttataatgc tccattatga tctgaagcat ttcctgagag agcgctccac
    10801 cttcaaataa aataaaggcg tttaacgttt cgtttcgctt aagccagtgg tctgccagtt
    10861 gttgttttga agtcatgatt acgctccttc aacaacagca tcatcgtttt tgatggcatt
    10921 cagcaggcat tcaagacaaa aatcggatga gtccacggct gaaaggatgg gaaattctgg
    10981 cataggaacc ttctccgaag ctttcggctg gcgtccgtag tgcaccgctt tgacgttata
    11041 atcccccggc gttcccggct caatgccgct accctctatc cggatataac ttccaccgcc
    11101 attaatcgtt atttttttct tcgctgaaat cctgatctcg tcctcagtac tgacgatctc
    11161 tatcgatttt ttcgccagta actccatcag atcgtgctgc gcctgtaccg atactgcgcc
    11221 tttattggca atcagtttga tacccgcctt gcgcacaaac acgctcagcg cccgccccac
    11281 gccgataaac atattcttca ccacgccgat atcggcgttg tttcccgcat ttatctggag
    11341 gtttttcacc gctgccagtt gcaggtgctc gccgctggcg accgccacgc ctttcggcgc
    11401 gtgcatcaaa atcaccgagg cggtcaggtc atttatccgg ctggttatca atgctatctg
    11461 cgcggccaca tccgccgggt cggcgttcgc cgtcgtcgcg tcatcggaca gtttctggat
    11521 tttatcgctc agaccgttca gttcgctgat aatgtcggcc atctctctga cctgaccctg
    11581 cgccttgtcc tgcgcatcgg cgctgataaa tatccctttc tttgcacgca ccgcgcccca
    11641 cagatcggta cgcagttcaa agccttcgcc gcgctgttct ttcccggcat caacaagatg
    11701 gccgaggttt agctggctct tgccgccata ttcggtactg accttgatat gctctttgcc
    11761 gcgctcgtca tccagccgga ttttgttgtt cgccggggtg cgcagcacgt tgcgcttgta
    11821 gttctgaatg gtcacatggt cggtgtgtgc cgagtcgtgt tttaccccgg cgatatacgg
    11881 tcggtccggg ttgccttcct caaaggcgat gctgacttcc gttcccgcca gcagcggcag
    11941 gtgcaggccg taggtgtctc ccgcatacgg gcgcgactgg cgtacccaca ggctttcgta
    12001 gcccggcttc cacgtatcac ggtcaaagtc gagattgacc cggtagcgcc cgtccttatc
    12061 gatatgggcg tagatgtcgt tcttcaccgt actggtgacc cgcgccggga gtgttccggc
    12121 cattacgggg cgggggataa gcgccgggcg atagccgtag cgttctgagt agggtatcgc
    12181 cgtgaacgtc agttcatagc tgcggtcacg ggccgcgctg gccgtcacgc cggtaatcag
    12241 cacgcccttg cggaataccg caggcgcgtc gtcgccctga accctgattt ccagccccgg
    12301 aatcagcagt gaactggtgc tctggccttt gagaatggcc tgttcattca ggtagcgttc
    12361 gtggcggata cgggcataaa acgcgccgct ttccgctgcc tctttatcgc ctttttgcag
    12421 gaagttgtca gcgtagtggt aggcttcgcc ataggtggtg ttatcgcccc cggtggcgtc
    12481 atgctgctct gtcatcatct ctgctgtggc ggtgcggtag ttgtagtccc gcgtggtgac
    12541 gcttttttcc accacgctgt atgcggtgtt cagcccccat acggcttccg tttcaccatc
    12601 aaacagccct gaaggatggc gaagcggcag cgtcagtccg cgctcatagc cgctctggtc
    12661 gtcataaaat tcgataactt cgattttcag ccgcgcgtct gtggcaaacc ggaaccagat
    12721 acccacttcc gacagcaggc gtgagacaaa cgtcaggtcg tcctcgccat actgcatcac
    12781 ctgttcgcgg gccgggtatt cgctttttag gttaaacacg aagtcctgac cgcgcatctg
    12841 gtgccgctcg cgcaggattt tttcgacgat ttgcggcacc gtcagattct ggtagatggc
    12901 attctggcgg ctgcgggtca gcagcgccat acggggttca agccgcactt cgtaacgggc
    12961 ttcatcctgt gacgaggaga gatgtttaaa gccggtaatg acgccataca gggtgcgcag
    13021 gggtgcctgc accggcattc cctgtaccgg cggtgccgtc aggcttaatg cgccgtcctg
    13081 catcagtacc gactccggcg tgatggcttt atcggtactg gtaaattcaa tgtcgtagcg
    13141 gaaggacgcg ctgagttgtt cccggcccgt aaaagtcagc acgtccaccg ggctttgcag
    13201 accgcgaatt ttaagcttgt ggtgtgagtg gtcgaaattc tgaataccca tgacagcctc
    13261 cgttattgca tctcttccgt agtgaactcc agtacaatcc cgtcttcctc atcccagcca
    13321 agctgtagtt gggctggttt acggtgcgcg gcctgctgcg ccagcaactg ctgacttagt
    13381 accggcagga tttgctggtt caacaggctg tcgatattgc gtgcaccggt gtccggcagc
    13441 aggcaggcgg cggtcagggc gtcatacagg ctgtcgttga tttccgtttc cagcccatag
    13501 tgctgacgaa gacgacgaac cacctgcgcc agtttcattt ccacaatagt gcgcatcgcc
    13561 tcctgtccca gcgggcggta aatcaccgtc tgaaaacgcg ccatcagcgc aggctggaag
    13621 tggtcgcgca gcaggggata cagcagttca tgcaggtctg cgtccgtggc gtccggtttt
    13681 tcctccagca gctgcatgat gtggtcgctg cccagattag ccgtcatcag aatcacggtg
    13741 ttgcggaaat caatttcccg cccttcgccg tcgcgcataa agccccgatc aaatacctga
    13801 tagaacaggt tcatcacgtc gcgatgcgcc ttttccactt cgtcgagcag caccacgctg
    13861 tacgggcgtt tgcgaacggc ttcggtgagt acgccgccct gaccgtagcc aacgtagccc
    13921 ggaggagacc ccttaagctg ggagacggta tgcggctcct gatattcgga gaggttgatg
    13981 gtgataaggg atttttcacc gccaaacagg gtgtcggcca gtgtgagcgc agtttcggtt
    14041 ttaccggtgc cgctggggcc ggtcagcagg aataccccct gcgggccgtt ctccggcgtg
    14101 aggccggttt tagccgcccg cagccgctgt gcgatggcgc agagcgccgg gctttgcccg
    14161 acaacgcggt tttcaaggct ttgttccata ctgagcaggt cgctctgctc gtccctgagc
    14221 agggaagaga gcgggatgcc ggtccagtcc gccaccacag tggcgacggc gcgggcgtcc
    14281 acatccagcg ccagcagcgg tgcaaagccc tgatgcgttc gcagttgctg ttgcaaatca
    14341 gtgctgtctg ccccttcctg acgcaacgcc ataatctgct gcgcaagccg cttttcctgc
    14401 tgatactgcg cttccagatg cccggcttct gcctgtagct catcacgcaa atcggtcagt
    14461 tccgccagcc gctccgggct ggtttcggga taaaacacgc tgtcctgctc aatcgcttcc
    14521 cgctcaatat ccagcgcggt cagacgcgcc tgaagctgcg tcaacggttc cggcagggtg
    14581 tcgaggctca tgcggactct tgccccggcg gtatccagca aatcaaccgc cttgtccggc
    14641 aactggcgtc cggtcagata gcggcgcgac aggcgcacgg cggtctgaat ggcgctgtcc
    14701 agcatatgta cgccgtggtg ctgtgcatag cgggccttga gtccccgcag catcaggcag
    14761 gcggtgtcat catccggctc gtcgactttc accatctgga agcggcgttc cagcgcggcg
    14821 tcgcgctcaa aatactgttt gtattcgctc cacgttgtgg cggcgatggt gcgcagttcg
    14881 ccccttgcca gcgccggttt cagcaggttc gccgcatccg cgccgcctgc ctgattaccc
    14941 gcaccgataa tggtatgggc ttcatcaata aacagcagta ccggctccgg tgatttctgc
    15001 actgcatcga tgacattttt cagccgctgt tcaaattcac ctttaacacc cgcgccagcc
    15061 tgtaacagac cgaggtccag tgtgcggata tgcaccgttt tcaggctgtc cggcacgttg
    15121 ccttcggcga tacgcagcgc cagcccttcc accagcgcgg ttttgcccac ccccggttct
    15181 cccaccagaa tcgggttgtt tttgcggcga cgtgagagga tatcgaccat ctggcgaatt
    15241 tccgtgtcgc gcccgaatac cgggtcgatt cgcccgctgc gggctttttc cgtcacgtct
    15301 tcggtaaagc ggttaagcac cgccagcagg gcgtcatcct gtttccccgt cagcgttttt
    15361 gccggtgcgt ccgtcgttgc cgcctctggt tgcgcggatg tcagcggttc ggtgacctgt
    15421 ggctgacgtg ccggacattc atccgactgt gcatccagca ggggacgcag ccgctcaagc
    15481 tgcacacggc tcaggctcag caatacccac aggtcattac aggcgggcag catcggtttt
    15541 tctgtcagcg ccatcagcag gtgctggctg cggatttgcg ggtcgtcgcc ttccagcgag
    15601 gcaatcagcc acgcctgcct gataagtgcc gtcaggggtt cagaaagctg cggacgttcg
    15661 cggaccgagc ggggtaaggt gtccagatgt gccagcagag actgccagag cgtgtcgata
    15721 tcccattcat agcggcgggc aatcaccgtg atatcgcctt ctccctgctc cagcagtttc
    15781 agcagccagt gttcaatggt tatctccgca tgggcgcggg tctgacacag tgaggcggca
    15841 gcgtccagcg cccgtgcaca gtacgggtta aggcgacgca gcagcgcggc ggggtgattt
    15901 ccggtcatag aaggtttcct tatcgtgttc tgtattcctg cgatctgcgt tcaggtacgc
    15961 taccgcccat agccgttacc tcactcaggc ccatcaggta tcaccagatt gtgggtatgc
    16021 tttgctcagt accggtgcct gcggcactgg gcaaagcaca caacagaaag gcagacagtt
    16081 tcctgtctgc cgcagttatc aggcggaagg acgttcattc cacgagtcgg aatgaatgat
    16141 gttgccgtct ttgtaagtcc aggtgatttt ttcgtagcgg aactcaatgc gttccaggtg
    16201 gttatgcttc tctttggaag gctccttgat gtcgtgcatc agcggagcga ctctgaccag
    16261 cttgacgtta tccagcgtga tgttgaagta ctccacttcc tgaccggcgt cgttgatgcg
    16321 gtaaaactta aattccgccg ttttcagggt ctgaccggtg gtcacagctt tgtagagata
    16381 cgggctggac gcatcgattt ctttggtaaa aatgaacggt ttatgggtgc gagtaccggt
    16441 cagtttgccg gtgttgttgt cggtcgggat gtacacatcg tgatccagcg ccaccacttc
    16501 gatgctgcct tcgcgcccct gaacgtccac ggaacctttg atatccgcgc cgccgtcatc
    16561 tttcagccag agataagcag gaatagccat gagaattact ctccttgtta gtgtgattga
    16621 agcaccgcct tcttccggcg gtatgtttta tttcacgtcc tgacaggcgt cagaacgcgg
    16681 aacaagactg atttcgacgc gccggttgac tgcccggccc tgtggcgtat cgttggtcgc
    16741 cgcaggctgg ctctcgccca gtccctgtac ggcaaaacag gtggccggga tgtcgctggt
    16801 ctgcagcatc cagttgcgca ccgcttcggc acgtcgcagc gataactgct gattgctttt
    16861 ttcgtcgccg gtggcgtcgg tatatccggc cacgaggatc agccagcccg gttttgcccg
    16921 gatgttcacc agtgcgtcca ccagcacttt tgtcgagccg tctttcaggc gggcctgtcc
    16981 gacgtcaaac agcgacatac tgtcaagacg cacggtctgc gcctgaagcg aggctgtcac
    17041 ttccattttt tgctcaggcg gacgccagtc acgaatggcg cgtaataccg gctggcggat
    17101 ttgttcaccg gggtataacc ccagaccgag acgcagtggc tctccttccc ggtaataccc
    17161 atcgagcatg atcgcatcgt ctttcagcac cgacagacga cgggctttgg tgataaattc
    17221 ctccgccgga acggcataaa actggtgcag atcatcaccg atatgccgta ataactggcg
    17281 attctccgtg gctgacagac acagcgcggc gatacccgcc acggtggtga tgcccagcat
    17341 ggtcacgcag gctcgtcgca gcggggtaaa gcccgactga cgcggcaacc gccgtaacag
    17401 ggcatccgga aacggcagcg tggcgtctgt gccggtgtcc gcgatatccg tcgtcaggcc
    17461 ggttctggcg gtgatccaca actgccacag gttgttatcc accgcaggca acgaggggac
    17521 cagccccacg gccatcgcca gtggcggaca tttcgtttcc gggccgttca gtgccgccag
    17581 catattaaga ttcagccact gcatcaggct ttcggctttc agcaggtaac agagttgctg
    17641 gctgcgctcc tgtgtgctgg tctgcgtgag ccactgcgcg ggggaggcgg tttcagcaga
    17701 cgtcgctaca tgaatttcgc cgccggtaca gataaaccac ggtgaattcg ctctctccgg
    17761 caacggcgag ccggacagcc cgctccagag aagccagggg acgtttacgc ccgcccggcg
    17821 acgcactgtc gccatactgt gggcgaaccg tcgcagtcgt ccggtcagaa ccgccgcatc
    17881 ccggtacatg ccgggcatga cggtatacgc cacggcaagc tgcgatgccc acgccgggcg
    17941 aagggtcagt aatcgctcca cctgcgccac aagctgttct tcatcgggaa catgcagata
    18001 cagcccttct gaaacctgcc ggaccgggct gtcagtgaac agatgcgccg acatatcgcc
    18061 acagaccagc actaccggtt gtcggtacgt ttccggcggc agcgatgaca acccggcatc
    18121 gccggtcatc tccgtccacg cctgcctgcg ccggtaaatc agcaacgcgg caaccgccag
    18181 aacgatagcc gccgccccgg cccatctcag tacgccagac ggactgataa acaccgacca
    18241 cagcaccagc agtaacacca ttccccacag cacgacggcc tgtttcagcg tgttcctcac
    18301 tcacgactcc ctttaccgca ggctttgcgg cagcaattca tccaccagca cgttcagcca
    18361 gtggtgcagc ccccaccaga caccggccag tagcagcgtc agcgttacca gccagaaaaa
    18421 cggcgaatgc agcaaagggt gctgacgggt ggataacggc acgttcagta ccgccgtttc
    18481 cggcagtacg ccaaatggcg cgaccagccc gttgagcgtc gaaataagct ggtcgcgctc
    18541 cggggccacc ggatcctgat aacgcccgcg aaatcccagc agcaggacac ggtgaaagca
    18601 ggtcagcaca gcctgtgcag gcgcgggctc ctgcaacacc tgcttcatcc gctcgtacag
    18661 cagctcgcct gcctgcaggg tgttgaagaa atgcgactgg agtggatcct tcatccagat
    18721 ggcctgaccg tcgtccatgc cgctgcgact caggactgtt tcgtccagca gggcgcactg
    18781 cgcgtaggta atgtgctcca cgctctcacg gctgaacccg gcatctttca ggcgttcgcg
    18841 gaccccctcc acctgccgct ggcagtggcg atacagctcc ataccgtgac gcacggtggt
    18901 tccctgacgc agttccacca ccgtcagaaa cgtgtcgcgc agcagcgcgt cgatattgat
    18961 atccgtctct tttttcatgt gcgcagcacc gcaaacagtt caggtttcag gtcgcccatg
    19021 gttcctggcg tataaatcat gcagcacccg gactccagca tcgatttagc cgcgtcactg
    19081 tgcatatcca gcgcaaaata ctgattctcc aggcgcagtg gcagcgctgc cggaactgag
    19141 gtcagtggca ccagtggaac accattcagc gccacgttga taagcagcgt gacgtcatca
    19201 ggcgcaccga ttttgcagac cagcggtagc tggtgcagta cctgatgcgc aggcagtgag
    19261 gaacgaacgg acaggtaaaa atcggcctct tcccgcaggc gcggatcgtg caggtcggct
    19321 ttccagcggt tgcccggcag ggatcccaga tccagcgcga tcacccgtga cggcaggctt
    19381 gcttccagca gttcgctgag cagggagaac agtggcggaa agacagtgga cggcgattcg
    19441 tggacatagg gcggaacggc gctgacgtta tgttcaaggg aaaacgtcag cagcgctccg
    19501 gcaagcctcg ccagctcccg ccagaccagt tcgggatgaa ccgccgggta gcgcaggaaa
    19561 tcactcagca ccggctcggc ggagttcagc gcgttaagca accagaacag ggagacatcg
    19621 gcgacggcga agtccgccat acgctggttg ctttcccgac gcatcgccat caggcgctga
    19681 catttggccc gtagctgcaa cagcagcgtg tccagacgct gtaccaaccc gtcatgagca
    19741 ttaaacgcca gtaacggcgg aatatagccc tcatcctgtg tccagttgcc ctgaacatcc
    19801 cgcaccagac gcgccagtgg gcaggtgatg taatcctgat tgttatcatg agcaaagcgc
    19861 agggacagcg catgacgctc aacggccata tcttcactgt cactgccgta gatatcctgt
    19921 accttttgcc attcctgacg atagcgtagc ggtctttcag tctgctcacc ctgaccgaga
    19981 ttaccgccgt taccatgggc aagcggcagc gccagcagaa caaccgcgct gtcgttcgtc
    20041 agcgcgtgca gatcgcaggc gagaggcaga acatcgctca cgtcagaatc gatcagcgtg
    20101 ccatcagcaa aacgcaggcg tactgcctgc gttttcagct ttccggacat cagggcatcg
    20161 cggtcaaaga gcacattcgc gatcccccac ggatgacgaa tacaaagttg cgcaatgctg
    20221 tcattgctga acgcttccca gcgggcctgc tgctgaaact gctgagagga caggaatgtc
    20281 ccctcagccc acagtggtcg atgaattttc atatcacacc acttcccggt caggctttcg
    20341 ctttcggcat ctgggaaacc agtgacaggt tgatatccat cccttcaatc tggaaatgcg
    20401 gcacggcaaa gagtctgacg cggaagaagc ccggattgtc ctcaatatct tccacgataa
    20461 ccttaccgtc gcgcagcggg tgagacgcct gcagttcatc acccggatcg gtcatctccg
    20521 tcaccagtgt gcggatccag gtgttcagtt ccagttccag tacgcggcgg tctttggtgg
    20581 taccgatatt ctcgcgctgg atgattttca ggtaatgcgc aatgcgggac agcaggaaga
    20641 tatagggcag acgggcgtta atacggctgt tggcggtggc gtcagcggta tcatacaacg
    20701 ccggtttctg ggcagagttt gccgagaaga agcaggcgta atcgcgattc ttataataag
    20761 agagcggaat aaagccaagg ttggaaaatt caaattcgcg ggtttccggg atcatcactt
    20821 cggacggaat tttgacctga ttgccggtgc cgagatcgta aagatggatg ggcagatcgg
    20881 ccactgcgcc acctgcttgt ggaccacgga tctgcacgca ccagccatta ttcacaaagc
    20941 tcttcaccat attggcggca aaggcgaacg aggcgtttgt ccagagatac ttttcgtgat
    21001 ccgggccttt gacttcttcc acatagttaa agctgcgtac cggcaccgtg tccggcccat
    21061 agggcagacg gcccagcact cgcggcatca ctaatcccac atagcggctg tcatcggtat
    21121 cacgaaacga tttccattta atatattctg cgcggtcaaa gtagttgccg atatctttaa
    21181 tcgcggcgac ttcttccatc gaatttttaa ggaagaattt cggcccgaca gaaccgataa
    21241 aaggcatatg ggaagcggca gacactctgg aaatattgcg cagcagggca atatcctgcg
    21301 ggctgttatc aaattcatag ctggaaatta atgaggcaac aggttcgcca cccggcgtat
    21361 cgtactcctg aatgtatgta tgacgatata aaccgctctg aatgatttcc ggggagtcgt
    21421 cgaaatcctg acgcagatgc tctttgctga tatccagcaa ttcaattctg acatttttgc
    21481 gaaaatcagt gcgctgtacg acgaaccatg tgccgcgcca cagcgactcg actttctgga
    21541 attcaggatg gtgcatgacc gcatcaagct gtttactgat tttctgatcc aaatcgtcga
    21601 tatgaaaatc cagcaggctc ttgtcgagct tgaccacgtt ctcgcctgat ttcgccagac
    21661 aggaaagtag aacgtgaatc gccgctgtca cgcgctcatc gggtgaggca tccgccagtg
    21721 tttcgctgtt ttgccataaa tctatttcct gaatggaaga caccggggtt aaattaattt
    21781 tatcaaacag ggactgataa acgccgccgg actcagtggt ggtcagtgtt gcagtttcag
    21841 aggtggcatg ttcttgttgt acagacatca gcatttcctt ttcagtgatc ctttcttctc
    21901 cggtttaacc tgaatatcac ttcgggttaa acgttctcct gcggcgcaat tttcgccagt
    21961 tcatcacgca gttctgaact gagcgtcggg tctttcagga tattttccag ttcacgtcga
    22021 aacgttgcgt tatctaacag attggatttc aggtcacgta ataaattgcg catagcgagt
    22081 aatacacgaa gctgtgggat attttttgct acctgttcgg gttcaaaatc tttcaggctt
    22141 ttaaattcaa gcgcgatatt ttgctcatta ccgcttccgc ttagtgtgtc ttctactgtt
    22201 aaattaaccg caggcgaaaa ctcagccatg acactgttga agttgttttt attgatatca
    22261 atcttgtccc gttcggacag cggacgttgc tcttttccgt tactgtaatc gccaacagca
    22321 agaagcttga gggggagttc aactttcttt ttagcattgc ctgtatgcag gtcaagcttg
    22381 atatttacac gagcggcggg aacttcattc tggaaactgt cggccatatc cttttcctca
    22441 tcatccactt tttctgatgg ttattgacat aattatattc acgggattat cgggtgattt
    22501 aaataaaaag caatgattag gaaa
//
LOCUS       DAPOAV010000075        22092 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.075, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000075 DAPOAV010000000
VERSION     DAPOAV010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22092
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.075"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            360..1166
                     /gene="xthA"
                     /locus_tag="RN951_003240"
     CDS             360..1166
                     /gene="xthA"
                     /locus_tag="RN951_003240"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HDX2528200.1"
                     /translation="MKFVSFNINGLRARPHQLEAIVEKHQPDVIGLQETKVHDDMFPL
                     EEVAKLGYNVFYHGQKGHYGVALLTKETPIAVRRGFPGDDEEAQRRIIMAEIPSLLGN
                     VTVINGYFPQGESRDHPIKFPAKAQFYQNLQNYLETELKRDNPVLIMGDMNISPTDLD
                     IGIGEENRKRWLRTGKCSFLPEEREWMDRLMSWGLVDTFRHANPQTADRFSWFDYRSK
                     GFDDNRGLRIDLLLASQPLAECCVETGIDYEIRSMEKPSDHAPVWATFRR"
     gene            1333..2043
                     /locus_tag="RN951_003241"
     CDS             1333..2043
                     /locus_tag="RN951_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416264.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDX2528201.1"
                     /translation="MNAERKFLFACLIFALVIYAIHAFGLFDLLTDLPHLQTLIRQSG
                     FFGYSLYILLFIIATLLLLPGSILVIAGGIVFGPLLGTLLSLIAATLASSCSFLLARW
                     LGRDLLLKYVGHSNTFQAIEKGIARNGIDFLILTRLIPLFPYNIQNYAYGLTTIAFWP
                     YTLISALTTLPGIVIYTVMASDLANEGITLRFILQLCLAGLALFILVQLAKLYARHKH
                     VDLSASRRSPLTHPKNEG"
     gene            2048..2725
                     /gene="ydjY"
                     /locus_tag="RN951_003242"
     CDS             2048..2725
                     /gene="ydjY"
                     /locus_tag="RN951_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416265.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YdjY"
                     /protein_id="HDX2528202.1"
                     /translation="MLQHYSVSWKKGLAALCLLAVAGLSGCDQQENAAAKVEYDGLSN
                     SQPLRVDANNHTVTMLVQINGRFLTDDTRHGIVFKDGSNGHKSLFMGYATPKAFYEAL
                     KEAGGTPGENMTMDNKETTHVTGSKLDISVNWQGAAKAYSFDEVIVDSNGKKLDMRFG
                     GNLTAAEEKKTGCLVCLDSCPVGIVSNATYTYGAVEKRGEVKFKGNASVLPADNTLAT
                     VTFKIAE"
     gene            2740..3447
                     /locus_tag="RN951_003243"
     CDS             2740..3447
                     /locus_tag="RN951_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDX2528203.1"
                     /translation="MMMMQSRKIWYYRITLIILLFAMLLAWALLPGVHEFINRSVAAF
                     AAVDQQGIERFIQSYGALAAVVSFLLMILQAIAAPLPAFLITFANASLFGAFWGGLLS
                     WTSSMAGAALCFFIARVMGREVVEKLTGKTVLDSMDGFFTRYGKHTILVCRLLPFVPF
                     DPISYAAGLTSIRFRSFFIATGLGQLPATIVYSWAGSMLTGGTFWFVTGLFILFALTV
                     VIFMAKKIWLERQKRNA"
     gene            3447..3995
                     /locus_tag="RN951_003244"
     CDS             3447..3995
                     /locus_tag="RN951_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HDX2528204.1"
                     /translation="MGLPPLSKIPLILRPQAWLHRRHYGEVLSPIRWWGRIPFIFYLV
                     SMFVGWLERKRSPLDPVVRSLVSARIAQMCLCEFCVDITSMKVAERTGSSDKLLAVAD
                     WRQSPLFSDEERLALEYAEAASVTPPTVDDALRTRLAAHFDAQALTELTALIGLQNLS
                     ARFNSAMDIPAQGLCRIPEKRS"
     gene            4005..5171
                     /locus_tag="RN951_003245"
     CDS             4005..5171
                     /locus_tag="RN951_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416268.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDX2528205.1"
                     /translation="MRHCGWLLGLLSLFSLATHASDWQEIKNEAKGQTVWFNAWGGDT
                     AINRYLDWVSGEMKTHYAINLKIVRLADAADAVKRIQTEAAAGRKTGGSVDLLWVNGE
                     NFRTLKEANLLQTGWAETLPNWRYVDTQLPVREDFSVPTQGAESPWGGAQLTFIARRD
                     VTPQPPQTPQALLEFAKANPGTVTYPRPPDFTGTAFLEQLLIMLTPDPAALKEAPDDA
                     TFARVTAPLWQYLDVLHPYLWREGKDFPPSPARMDALLKAGTLRLSLTFNPAHAQQKI
                     ASGDLPASSYSFGFREGMIGNVHFVTIPANANASAAAKVVANFLLSPDAQLRKADPAV
                     WGDPSVLDPQKLPDGQRESLQSRMPQDLPPVLAEPHAGWVNALEQEWLHRYGTH"
     gene            5144..6679
                     /locus_tag="RN951_003246"
     CDS             5144..6679
                     /locus_tag="RN951_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416269.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDX2528206.1"
                     /translation="MATPLRYALIFLLWAMVAVIYAPLIPAALTLISPALSLTHWQAL
                     FADPQLPQALLATLVSTTIAAVGALLIALLVIVALWPGPKWQRMCARLPWLLAIPHVA
                     FATSALLLFADGGLLYDYFPYFTPPMDRFGIGLGLTLAVKESAFLLWILAAVLSEKWL
                     LQQVIVLDSLGYSRWQCLNWLLLPSVAPALAMAMLAIVAWSLSVVDVAIILGPGNPPT
                     LAVISWQWLTQGDIDQQTKGALASLLLMLLLAAYVLLSYLLWRSWRRTIPRVDGVRKP
                     ATPLLPGNTLAIFLPLTGVLCVVLLAILADQSTINSEALINSLTMGLVATFIALLLLL
                     LWLEWGPQRRQLWLWLPILLPALPLVAGQYTLALWLKLDGSWTAVVWGHLLWVMPWML
                     FILQPAWQRIDSRLILIAQTLGWSRAKIFFYVKCPLMLRPVLIAFAVGFAVGIAQYMP
                     TLWLGAGRFPTLTTEAVALSSGGSNGILAAQALWQLLLPLIIFALTALVAKWVGYVRQ
                     GLR"
     gene            6679..7332
                     /locus_tag="RN951_003247"
     CDS             6679..7332
                     /locus_tag="RN951_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDX2528207.1"
                     /translation="MLCVKNVSLRLPESRLLTNVNFTVDKGDIVTLMGPSGCGKSTLF
                     SWMIGALAEQFSCTGELWLNEQRIDILPTAQRQIGILFQDALLFDQFSVGQNLLLALP
                     ATLKGNARRNAVNDALERSGLEGAFHQDPATLSGGQRARVALLRALLAQPKALLLDEP
                     FSRLDVALRDNFRQWVFSEVRALAIPVVQVTHDLQDVPADSSVLDMAQWSENYNKLR"
     gene            7399..8706
                     /gene="ynjE"
                     /locus_tag="RN951_003248"
     CDS             7399..8706
                     /gene="ynjE"
                     /locus_tag="RN951_003248"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416271.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase YnjE"
                     /protein_id="HDX2528208.1"
                     /translation="MKRVSQMTALAMALGLACASSWAAELAKPLTLDQLQQQNGKAID
                     TRPSAFYNGWPQTLNGPSGHEPAALNLSASWLDKMSTEQLNAWIKQHNLKTDAPVALY
                     GNDKDVDAVKTRLQKAGLTHISILSDALSEPSRLQKLPHFEQLVYPQWLHDLQQGKEV
                     TAKPAGDWKVIEAAWGAPKLYLISHIPGADYIDTNEVESEPLWNKVSDEQLKAMLAKH
                     GIRHDTTVILYGRDVYAAARVAQIMLYAGVKDVRLLDGGWQTWSDAGLPVERGTPPKV
                     KAEPDFGVKIPAQPQLMLDMEQARGLLHRQDASLVSIRSWPEFIGTTSGYSYIKPKGE
                     IAGARWGHAGSDSTHMEDFHNPDGTMRSADDITAMWKAWNIKPEQQVSFYCGTGWRAS
                     ETFMYARAMGWKNVSVYDGGWYEWSSDPKNPVATGERGPDSSK"
     gene            complement(8715..9335)
                     /locus_tag="RN951_003249"
     CDS             complement(8715..9335)
                     /locus_tag="RN951_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416272.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HDX2528209.1"
                     /translation="MLDRHLHPRIKPLLHQCVRVLDKPGITPDGLTLVGFAIGVLALP
                     FLALGWYLAALVVILLNRLLDGLDGALARRRELTDAGGFLDISLDFLFYALVPFGFIL
                     AAPEQNALAGGWLLFAFIGTGSSFLAFAALAAKHQIDNPGYAHKSFYYLGGLTEGTET
                     ILLFVLGCLFPAWFAWFAWIFGALCWMTTFTRVWSGYLTLKSLQRQ"
     gene            9422..9829
                     /gene="nudG"
                     /locus_tag="RN951_003250"
     CDS             9422..9829
                     /gene="nudG"
                     /locus_tag="RN951_003250"
                     /EC_number="3.6.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP pyrophosphohydrolase"
                     /protein_id="HDX2528210.1"
                     /translation="MKMIEVVAAIIERDGKILLAQRPAQSDQAGLWEFAGGKVEPDES
                     QRQALVRELREELGIEATVGEYVASHQREVSGRIIHLHAWHVPDFHGTLQAHEHQALV
                     WCSPEEALQYPLAPADIPLLEAFMALRAARPED"
     gene            complement(9795..10067)
                     /locus_tag="RN951_003251"
     CDS             complement(9795..10067)
                     /locus_tag="RN951_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnjH family protein"
                     /protein_id="HDX2528211.1"
                     /translation="MSRALFAVVLAFPLIALANPHYRPDVEVNVPPEVFSSGGQSAQP
                     CTQCCVYQDQNYSEGAVIKAEGILLQCQRDDKTLSTNPLVWRRVKP"
     gene            10303..11646
                     /gene="gdhA"
                     /locus_tag="RN951_003252"
     CDS             10303..11646
                     /gene="gdhA"
                     /locus_tag="RN951_003252"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HDX2528212.1"
                     /translation="MDQTYSLESFLNHVQKRDPNQTEFAQAVREVMTTLWPFLEQNPK
                     YRQMSLLERLVEPERVIQFRVVWVDDRNQIQVNRAWRVQFSSAIGPYKGGMRFHPSVN
                     LSILKFLGFEQTFKNALTTLPMGGGKGGSDFDPKGKSEGEVMRFCQALMTELYRHLGA
                     DTDVPAGDIGVGGREVGFMAGMMKKLSNNTACVFTGKGLSFGGSLIRPEATGYGLVYF
                     TEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITASDSSGTVVDESGFTK
                     EKLARLIEIKASRDGRVADYAKEFGLVYLEGQQPWSLPVDIALPCATQNELDVDAAHQ
                     LIANGVKAVAEGANMPTTIEATELFQQAGVLFAPGKAANAGGVATSGLEMAQNAARLG
                     WKAEKVDARLHHIMLDIHHACVEHGGEGEQTNYVQGANIAGFVKVADAMLAQGVI"
     gene            complement(11763..12803)
                     /locus_tag="RN951_003253"
     CDS             complement(11763..12803)
                     /locus_tag="RN951_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416276.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HDX2528213.1"
                     /translation="MKKVLLQNHPGSEKYSFNGWEIFNSNFERMIKENKAMLLCKWGF
                     YLTCVVAVMFVFAAITSNGLNERGLITAGCSFLYLLIMMGLIVRAGFKAKKEQLHYYQ
                     AKGIEPLSIEKLQALQLIAPYRFYHKQWSETLEFWPRKPEPGKDTFQYHVLPFDSIDI
                     ISKRRESLEDQWGIEDSESYCALMEHFLSGDHGANTFKANMEEAPEQVIALLNKFAVF
                     PSDYISDCANHSSGKSSAKLIWAAELSWMISISSTAFQNGTIEEELAWHYIMLASRKA
                     HELFESEEDYQKNSQMGFLYWHICCYRRKLTDAELEACYRYDKQFWEHYSKKCRWPIR
                     NVPWGASSVKYS"
     gene            complement(12931..14892)
                     /gene="topB"
                     /locus_tag="RN951_003254"
     CDS             complement(12931..14892)
                     /gene="topB"
                     /locus_tag="RN951_003254"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDX2528214.1"
                     /translation="MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGH
                     LLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHEASEIVHAG
                     DPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRSNSEFVPLCV
                     SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVA
                     KDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIV
                     TSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCR
                     YLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSA
                     INLTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDIAKGKFVAKARFLAEAGWRTLL
                     GSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ
                     DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHSLPEMAT
                     RPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVRQFRGIVAPGSGG
                     SADKKKAAPRKRSAKKSPPADEVGSGAIA"
     gene            complement(14897..15940)
                     /gene="selD"
                     /locus_tag="RN951_003255"
     CDS             complement(14897..15940)
                     /gene="selD"
                     /locus_tag="RN951_003255"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HDX2528215.1"
                     /translation="MSENSIRLTQYSHGAGCGCKISPKVLETILHSEQAKFVDPNLLV
                     GNETRDDAAVYDLGNGTSVISTTDFFMPIVDNPFDFGRIAATNAISDIFAMGGKPIMA
                     IAILGWPINKLSPEIAREVTEGGRYACRQAGIALAGGHSIDAPEPIFGLAVTGIVPTE
                     RVKKNSTAQAGCKLFLTKPLGIGVLTTAEKKSLLKPEHQGLATEVMCRMNIAGASFAN
                     IEGVKAMTDVTGFGLLGHLSEMCQGAGVQARVDYEAIPKLPGVEEYIKLGAVPGGTER
                     NFASYGHLMGEMPREVRDLLCDPQTSGGLLLAVMPEAENEVKATAAEFGIELTAIGEL
                     VPARGGRAMVEIR"
     gene            complement(16057..16608)
                     /locus_tag="RN951_003256"
     CDS             complement(16057..16608)
                     /locus_tag="RN951_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H nitroreductase"
                     /protein_id="HDX2528216.1"
                     /translation="MDALELLINRRSASRLAEPAPTGEQLQNILRAGMRAPDHKSMQP
                     WHFFVIEGEGRERFSAVLEQGAIAAGSDDKAIDKARNAPFRAPLIITVVAKCEENHKV
                     PRWEQEMSAGCAVMAMQMAAVAQGFGGIWRSGALTESPVVREAFGCREQDKIVGFLYL
                     GTPQLKASTSINVPDPTPFVTYF"
     gene            16769..18625
                     /gene="sppA"
                     /locus_tag="RN951_003257"
     CDS             16769..18625
                     /gene="sppA"
                     /locus_tag="RN951_003257"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HDX2528217.1"
                     /translation="MRTLWRFIAGFFKWTWRLLNFVREMVLNLFFIFLVLVGVGIWMQ
                     VSGGDSKETASRGALLLDISGVIVDKPDSSQRFSKLSRQLLGASSDRLQENSLFDIVN
                     TIRQAKDDRNITGIVMDLKNFAGGDQPSMQYIGKALKEFRDSGKPVYAVGENYSQGQY
                     YLASFANKIWLSPQGVVDLHGFATNGLYYKSLLDKLKVSTHVFRVGTYKSAVEPFIRD
                     DMSPAAREADSRWIGELWQNYLNTVAANRQIPAEQVFPGAQGLLEGLTKTGGDTAKYA
                     LENKLVDALASSAEIEKALTKEFGWSKTDKNYRAISYYDYALKTPADTGDSIGVVFAN
                     GAIMDGEETQGNVGGDTTAAQIRDARLDPKVKAIVLRVNSPGGSVTASEVIRAELAAA
                     RAAGKPVVVSMGGMAASGGYWISTPANYIVANPSTLTGSIGIFGVITTVENSLDSIGV
                     HTDGVSTSPLADVSITRALPPEAQLMMQLSIENGYKRFITLVADARHSTPEQIDKIAQ
                     GHVWTGQDAKANGLVDSLGDFDDAVAKAAELAKVKQWHLEYYVDEPTFFDKVMDNMSG
                     SVRAMLPDAFQAMLPAPLASVASTVKSESDKLAAFNDPQNRYAFCLTCANMR"
     gene            18792..19808
                     /gene="ansA"
                     /locus_tag="RN951_003258"
     CDS             18792..19808
                     /gene="ansA"
                     /locus_tag="RN951_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HDX2528218.1"
                     /translation="MQKKSIYVAYTGGTIGMQRSEQGYIPVSGHLQRQLALMPEFHRP
                     EMPDFTIHEYTPLMDSSDMTPEDWQHIAEDIKAHYDDYDGFVILHGTDTMAYTASALS
                     FMLENLGKPVIVTGSQIPLAELRSDGQINLLNALYVAANYPINEVTLFFNNRLYRGNR
                     TTKAHADGFDAFASPNLPPLLEAGIHIRRLNTPPAPHGEGELIVHPITPQPIGVVTIY
                     PGISADVVRNFLRQPVKALILRSYGVGNAPQNKAFLQELQEASDRGIVVVNLTQCMSG
                     KVNMGGYATGNALAHAGVIGGADMTVEATLTKLHYLLSQELDTETIRKAMSQNLRGEL
                     TPDD"
     gene            19819..20460
                     /locus_tag="RN951_003259"
     CDS             19819..20460
                     /locus_tag="RN951_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416282.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyrazinamidase/nicotinamidase"
                     /protein_id="HDX2528219.1"
                     /translation="MPPRALLLVDLQNDFCAGGALAVPEGDSTVDVANRLIDWCQSRG
                     EAVIASQDWHPANHGSFASQHGVEPYTPGQLDGLPQTFWPDHCVQNSEGAQLHPLLHQ
                     KAIAAVFHKGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFT
                     VLDALQLGYKVNVITDGCRGVNIQPQDSAHAFMEMSAAGATLYTLADWEETQG"
     gene            complement(20553..21911)
                     /locus_tag="RN951_003260"
     CDS             complement(20553..21911)
                     /locus_tag="RN951_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2528220.1"
                     /translation="MEQYDQIGARLDRLPLARFHYRIFGIISFSLLLTGFLSYSGNVV
                     LAKLVSNGWSNNFLNAAFTSALMFGYFIGSLTGGFIGDYFGRRRAFRINLLIVGIAAT
                     GAAFVPDMYWLIFFRFLMGTGMGALIMVGYASFTEFIPATVRGKWSARLSFVGNWSPM
                     LSAAIGVVVIAFFSWRIMFLLGGIGILLAWFLSGKYFIESPRWLAGKGQIAGAECQLR
                     EVEQQIEREKSIRLPPLTSYQSNSKVKVIKGTFWLLFKGEMLRRTLVAITVLIAMNIS
                     LYTITVWIPTIFVNSGIDVDKSILMTAVIMIGAPVGIFIAALIIDHFPRRLFGSTLLI
                     IIAVLGYIYSIQTTEWAILIYGLVMIFFLYMYVCFASAVYIPELWPTHLRLRGSGFVN
                     AVGRIVAVFTPYGVAALLTHYGSITVFMVLGVMLLLCALVLSIFGIETRKVSLEEISE
                     VN"
BASE COUNT         5347 a         5750 c         5601 g         5394 t
ORIGIN      
        1 cagccagtga taaaagtgca taaacggcgg aggctaactg gaaatcaagg agttataacc
       61 aaaccatatg catttaaagt gcatataaag tgaatacgtt tgcgatgtgg gtgaataaaa
      121 agaataaaaa acgcaatgtt atgcagaagt aaaatataat tctggaattg tgatcattga
      181 cgaaatttac tggaaattac tgcgccattc tgacgcagcg cgcaccaaaa gcgggcattt
      241 tttgcgccat cgttgacatc attaacaacc atcgatcaaa tcacttaaca acaggcggta
      301 agcaacgcga aattctgcta ccatccacgc actctttatc tgaataaatg gcagcgacta
      361 tgaaatttgt ctcttttaat atcaacggcc tgcgcgccag acctcaccag cttgaagcca
      421 tcgtcgaaaa gcaccaaccg gatgtgattg gcctgcagga gacaaaagtt catgacgata
      481 tgtttccgct cgaagaggtg gcgaagctcg gctacaacgt gttttatcac gggcagaaag
      541 gccattatgg cgtggcgctg ctgaccaaag agacgccgat tgccgtgcgt cgcggctttc
      601 ccggtgacga cgaagaggcg cagcggcgga ttattatggc ggaaatcccc tcactgctgg
      661 gtaatgtcac cgtgatcaac ggttacttcc cgcagggtga aagccgcgac catccgataa
      721 aattcccggc aaaagcgcag ttttatcaga atctgcaaaa ctacctggaa accgaactca
      781 aacgtgataa tccggtactg attatgggcg atatgaatat cagccctaca gatctggata
      841 tcggcattgg cgaagaaaac cgtaagcgct ggctgcgtac cggtaaatgc tctttcctgc
      901 cggaagagcg cgaatggatg gacaggctga tgagctgggg gttggtcgat accttccgcc
      961 atgcgaatcc gcaaacagca gatcgtttct catggtttga ttaccgctca aaaggttttg
     1021 acgataaccg tggtctgcgc atcgacctgc tgctcgccag ccaaccgctg gcagaatgtt
     1081 gcgtagaaac cggcatcgac tatgaaatcc gcagcatgga aaaaccgtcc gatcacgccc
     1141 ccgtctgggc gaccttccgc cgctaattta gcagctctcc tggctcaaac tgggtcagga
     1201 gaattaacct tgagaaaaat caacaaactg tcagtaatga tttgttgcct gccgtccttt
     1261 gttataccgt ctctgcgttt ttagttgtct gaccacttct ctattatcaa gtttgatata
     1321 ggaaactcca cgatgaacgc tgagcgtaaa tttctttttg cctgtcttat ttttgcgctg
     1381 gtcatttacg ctatccacgc tttcggttta ttcgatctgc tcaccgattt accccactta
     1441 cagacactca tccgccagag cggatttttc ggctatagcc tctatattct gttattcatc
     1501 attgccaccc tcttgctgtt accaggaagc atactggtga tcgcgggagg aatagttttt
     1561 ggcccgctct tagggacact actctcatta attgccgcca cgctggcctc ctcgtgctca
     1621 ttcctgctgg cgcgctggct gggacgtgat ttactgctga aatacgttgg ccatagcaat
     1681 accttccagg ccattgaaaa aggcattgcg cgtaacggta ttgattttct tattctgacc
     1741 cgcttaatcc cgttgtttcc ttacaatatt caaaattacg cttacggatt aaccacaatc
     1801 gccttctggc cttataccct tatttcggca ctcacgaccc tacccggtat tgttatttat
     1861 accgtgatgg caagcgatct cgccaatgaa ggcattacgc tgcgctttat tttacaactc
     1921 tgtctggcgg gcctggcgct gtttattctc gtccagctcg caaaactcta cgcccgacac
     1981 aaacatgtgg atctgtctgc ttcgcgccgc agcccactta ctcacccaaa aaatgaagga
     2041 tagaacgatg ttgcaacatt attcagtgtc atggaaaaaa ggactggctg cactctgttt
     2101 actggctgtt gctgggctta gcggctgcga tcaacaagag aatgcggcgg caaaagtgga
     2161 atacgacgga ctttcgaaca gccaaccgct gcgtgtcgat gccaataacc atacggtaac
     2221 catgctggtg caaattaatg gtcgtttcct caccgacgac actcgtcacg gtattgtgtt
     2281 taaagatggc tccaacggac ataaatcgct gtttatgggt tatgcgaccc cgaaagcatt
     2341 ttatgaagcc ctgaaagagg caggtggtac gccgggcgaa aacatgacga tggataataa
     2401 agaaacgact catgtcacag gcagcaaact ggatatttcg gtcaactggc aaggggcggc
     2461 aaaagcgtat tccttcgatg aagtgattgt tgacagtaat ggcaagaaac tggacatgcg
     2521 ctttggcggt aatttaacgg cagcagaaga gaagaaaacg ggttgcctgg tgtgtctgga
     2581 tagctgcccg gtcggcatcg tcagcaatgc aacatacact tatggtgcgg ttgaaaaacg
     2641 tggtgaagtt aaattcaaag gcaatgcctc agttctcccg gcggataaca cgctggcaac
     2701 ggttaccttt aaaatcgccg aataaagcca ggataaagga tgatgatgat gcaatcgcga
     2761 aaaatctggt actaccgtat aaccctcatc atcctgttgt tcgctatgct gctggcatgg
     2821 gcgctgcttc ccggcgtcca tgagtttatc aatcgcagcg ttgcggcgtt tgccgccgtg
     2881 gaccaacagg gtatagaacg ctttattcag tcttacggcg cactggcggc agttgtctcg
     2941 ttcttgttga tgattttgca ggccattgct gcaccgctac ctgcgttttt gatcaccttt
     3001 gccaatgcgt cgctgtttgg cgcgttctgg ggcggcttgc tgtcgtggac cagttcgatg
     3061 gccggcgcgg cgctgtgctt ttttatcgcc agagtgatgg gccgcgaagt ggtggaaaaa
     3121 ttaaccggca aaaccgtgct tgacagtatg gacggctttt tcactcgcta cggcaaacac
     3181 accattctgg tctgtcggtt attgcctttt gtccctttcg atccaatcag ctatgctgcc
     3241 ggtttgactt caatacgttt tcgctcgttt tttatcgcca ccgggcttgg tcagttaccg
     3301 gcaactattg tttattcctg ggcgggcagc atgttaacag gcggtacttt ctggtttgtc
     3361 accggactgt ttattctgtt tgccctgacc gtggtgattt ttatggcgaa gaaaatatgg
     3421 cttgaacgcc agaagaggaa tgcctgatgg gtttaccgcc gcttagcaaa attcctttaa
     3481 ttttacgtcc acaggcgtgg ctgcatcgtc gccattacgg cgaggtgcta agccccattc
     3541 gctggtgggg gcggatcccg tttatctttt atctggtgtc gatgtttgtt ggctggctgg
     3601 agcgcaaacg ctcaccgctc gatccggtag tacgatcgct tgtcagcgcg cgcattgcgc
     3661 aaatgtgcct gtgtgagttt tgtgtggata tcaccagtat gaaagtcgcc gagcgcaccg
     3721 gcagcagcga taaactgctg gcagtggctg actggcggca aagcccgctc tttagcgatg
     3781 aagaacggct ggcgctggag tacgccgaag ccgcaagcgt aacgccgcca acggtcgatg
     3841 atgccctgcg tacccgactg gctgcgcatt ttgacgctca ggcgctcacc gaactgacgg
     3901 cattgatcgg cctgcaaaat ctgtcagccc gttttaattc tgccatggac attcccgctc
     3961 aggggctgtg ccgtattcct gaaaaacgtt cttaaggaga gatgatgcgc cattgtgggt
     4021 ggttgctggg attgttatcg ctgttttctc tggcaacaca tgccagtgac tggcaagaaa
     4081 ttaaaaatga ggccaaaggg caaaccgtct ggtttaacgc ctggggcggc gataccgcaa
     4141 ttaaccgcta tctcgactgg gtgagcggcg agatgaaaac ccattacgct ataaacctga
     4201 agattgtccg tctggcggat gccgcagacg cggtgaagcg cattcagacc gaagccgcag
     4261 ccggacgtaa aacgggcggc tcggtggatc tgctctgggt gaacggcgaa aacttccgca
     4321 ccttaaaaga ggccaattta ttacaaacgg gctgggcgga gactctgccc aactggcgct
     4381 atgtcgacac acagctgccg gtgcgggaag atttttctgt gccgacacaa ggtgcggaat
     4441 cgccctgggg cggcgcacaa ctgacgttta tcgcccgccg cgatgttacg ccacagccac
     4501 cacaaacgcc gcaagcctta ctggagtttg ctaaagccaa tcccggcacg gttacctatc
     4561 cgcgcccacc ggactttacc ggcacggcgt ttcttgaaca gttgctgatt atgctgacgc
     4621 ccgatcccgc cgcattaaaa gaagcgccgg acgatgcgac tttcgcccgt gtcactgctc
     4681 ccttgtggca atatcttgat gtgctgcatc cgtatttgtg gcgcgaagga aaggatttcc
     4741 cgccttcacc cgcgcggatg gatgctctgc tgaaagccgg cacattgcgc ctgtcgctga
     4801 cctttaaccc cgcgcatgcg cagcaaaaaa tcgccagcgg cgatttgcct gcaagcagtt
     4861 acagttttgg ctttcgcgag gggatgattg gcaacgtgca tttcgtcacc attcctgcca
     4921 acgcgaatgc cagtgctgcg gcgaaggtag ttgccaattt cctgctctca cccgatgcgc
     4981 aactgcgtaa agcagatccc gctgtctggg gcgatccttc tgttctcgat ccgcaaaaac
     5041 tgcctgacgg gcagcgcgaa tcattgcaat caagaatgcc gcaggatctg ccgccggtac
     5101 tggctgaacc gcacgcaggt tgggtaaatg cgctggaaca agaatggcta caccgttacg
     5161 gtacgcatta atctttttgc tgtgggcgat ggtggcggtg atttatgcac cgctgatccc
     5221 ggcagctctc acgctgatat cgcctgcttt gtcgttgaca cactggcagg cgttatttgc
     5281 cgatccacag ttaccgcagg cattactggc aacgctggtg tcgacaacca tcgcggcggt
     5341 cggggcattg ttgattgccc tgctggtgat tgtggcgctg tggcctgggc cgaaatggca
     5401 gcgtatgtgc gcccgtctgc cgtggctgct cgccattccc catgtggctt ttgccaccag
     5461 cgcccttctg ctctttgctg acggagggct gctttatgac tatttcccgt atttcactcc
     5521 gccaatggac cgatttggca tcggtctggg cctcaccctt gcagtgaaag aaagcgcatt
     5581 tctgctgtgg atcttagcag cagtattgag cgaaaaatgg ctgttgcagc aggtcattgt
     5641 gctggattcg ctgggctaca gccgctggca atgcctgaac tggctgctgt tgccctccgt
     5701 cgcgcctgcg ctggcaatgg cgatgctggc gattgttgcc tggtcgctgt cggtcgtgga
     5761 tgtggcaatt attctcgggc caggtaatcc cccgacgctg gcggtaatta gctggcagtg
     5821 gttaacccag ggcgacattg accaacaaac aaaaggcgcg cttgccagcc tgctgttgat
     5881 gctgttactc gccgcctacg ttttgctgag ctatctgcta tggcgcagct ggcggcgcac
     5941 tattccccgc gtagatggcg ttcgcaagcc tgccacgcct ttattgccgg gcaatacgct
     6001 ggcgattttt ttacccttaa ccggtgtgct gtgtgtggtt ctgctggcga tcctcgcgga
     6061 tcagtcgacg atcaatagtg aagcgctcat caacagcctg acaatggggc tggtggcgac
     6121 attcatcgct ttgctcctgt tactgctgtg gctggaatgg gggccacagc gtcgccagtt
     6181 gtggctatgg ttgcccattt tattacctgc tctgccactg gtggcgggcc agtacacgct
     6241 ggcgctatgg ctgaaactgg atggaagctg gacggcggtg gtctgggggc atctgctgtg
     6301 ggtgatgccg tggatgctgt ttatcctgca acccgcctgg cagcgcattg attcacggtt
     6361 aattttgatt gcgcaaacac tgggctggtc gcgggccaaa atcttctttt acgtgaaatg
     6421 cccactcatg ttgcgccctg tgctgattgc cttcgcggtg ggatttgcag tcggtattgc
     6481 gcagtatatg ccaacgctgt ggctgggcgc ggggcgtttt ccgacgctca ccactgaggc
     6541 ggtggcatta agcagcggcg gcagcaacgg tattctcgcc gcccaggctt tatggcaact
     6601 gctattaccg cttattattt ttgccctgac cgcgttagtc gcaaaatggg taggttatgt
     6661 cagacaagga ctccgctaat gctctgcgtg aaaaatgttt cgctacgttt accagaaagc
     6721 cgcttgctga caaacgttaa ctttacggtg gataaaggtg acattgtcac gttaatgggg
     6781 ccgtctggct gtggaaaatc cactctgttt tcatggatga ttggtgcact ggccgaacag
     6841 ttttcttgta caggtgagct atggctcaat gagcaacgga ttgacatcct acccaccgca
     6901 cagcgtcaga ttggcattct ttttcaggat gcactgttat ttgaccagtt cagtgtcggg
     6961 caaaatttac tgctggcgct accggcgaca cttaaaggga atgcccgacg taatgccgtg
     7021 aatgatgcac ttgagcgttc aggccttgag ggagctttcc atcaggatcc tgccactttg
     7081 tctggcggtc agcgagcgcg cgttgctcta ctacgcgccc ttctcgccca accaaaagcg
     7141 ttactcctgg atgagccatt cagccgtctt gatgtggctc tgcgcgataa ttttcgccag
     7201 tgggtgttca gcgaagttcg cgccctggcg atccccgtcg ttcaggtaac gcacgatctc
     7261 caggatgttc ctgctgatag ttctgttctg gatatggcgc agtggtcaga aaattacaac
     7321 aaactgcgat aacgcaaagt ttttctcaat gcgtcagttc agaatggcgc actcaaaact
     7381 acaatgtcgg gattttcgat gaaacgtgtt tctcaaatga ccgcgctggc aatggcttta
     7441 gggctggctt gcgcttcttc gtgggccgct gaactggcga agcctcttac acttgaccag
     7501 cttcaacaac aaaatggcaa agcgatagat actcgcccca gcgcgtttta taacggctgg
     7561 ccacaaacct taaatggccc ttctggtcat gaacctgccg ccttaaacct ctctgccagc
     7621 tggcttgaca aaatgagcac cgaacagctc aacgcgtgga tcaagcaaca taacctgaaa
     7681 accgatgctc cggtggcgct gtacggtaat gacaaagatg tcgacgccgt caaaacgcga
     7741 ctgcaaaaag caggtttaac gcatatctcc atcctgagtg acgcgctaag cgaaccttcc
     7801 cgtctgcaaa aactgccgca ttttgagcag ctggtttatc cgcaatggct gcacgacctg
     7861 caacaaggta aagaggttac ggcgaaacct gccggtgact ggaaagtcat tgaagcggcc
     7921 tggggcgctc ctaagcttta ccttatcagc catattcccg gcgctgacta catcgatacc
     7981 aacgaagtgg aaagtgaacc gctgtggaac aaagtttctg atgaacaact aaaagcgatg
     8041 ctggcaaaac acggcattcg ccatgacacc acggtcattc tgtatgggcg tgacgtatac
     8101 gctgcagcgc gtgtggcgca gattatgctt tatgctggcg tgaaagatgt gcgcctgctg
     8161 gatggcggct ggcaaacctg gtccgacgcg ggactgcctg ttgagcgcgg aacgccaccg
     8221 aaagtgaaag cggaaccgga tttcggcgtg aagatcccgg cacaaccgca gttgatgctc
     8281 gatatggaac aggcccgtgg actgctgcat cgccaggatg catcgctggt gagcattcgt
     8341 tcgtggccag aatttatcgg tacgaccagc ggttacagct atattaaacc aaaaggtgaa
     8401 atagccggcg cacgttgggg acacgctggt agcgactcga cgcatatgga agattttcat
     8461 aacccggatg gcaccatgcg cagcgccgat gatattaccg ctatgtggaa agcgtggaat
     8521 atcaaaccag agcagcaagt ttcattctac tgcggcaccg gctggcgcgc gtccgaaacc
     8581 tttatgtacg cacgcgccat gggttggaag aatgtttccg tgtatgacgg cggctggtac
     8641 gaatggagca gcgatccaaa aaatccggta gcaaccggtg aacgcggccc ggacagtagc
     8701 aaataacatt gcaattactg acgctggagc gacttcagcg tcagataccc actccacacc
     8761 cgcgtaaagg tcgtcatcca gcacaacgca ccgaagatcc acgcaaacca cgcaaaccat
     8821 gcagggaata aacatcccag cacaaacagt aagatcgttt ctgtgccttc ggttaatccc
     8881 cccagatagt aaaacgactt atgtgcataa ccggggttat caatctgatg ttttgctgcc
     8941 agtgcagcaa aggcgagaaa actgctgccc gtgccgataa acgcaaacaa caaccagccg
     9001 cctgccagcg cattttgctc cggtgcagca agaataaagc caaacggcac cagcgcgtaa
     9061 aagagaaaat cgagagaaat atcaagaaag ccgcccgcgt cggtaagctc tctgcgccgc
     9121 gccagcgcac cgtccagacc atcaagcagc ctgttcaaca aaatgacgac tagcgccgcc
     9181 agataccagc ccagcgccag aaacggcaga gccagcacgc cgatggcaaa tcccactaat
     9241 gttaaaccat ctggcgtaat gcccggttta tcaagaaccc gcacgcactg atgcaacaac
     9301 ggtttaatcc ggggatgaag atggcggtct agcacaggca ctccttaaat ataaagcctt
     9361 tctgattgag caacagtgcg gatattatgg catttttcgc ttatctgccc gtgtgtaatt
     9421 tatgaaaatg attgaagttg ttgccgccat cattgaacgt gatggcaaaa ttttactcgc
     9481 gcaacgcccc gcccagagcg atcaggcggg attatgggag tttgccggtg gtaaagtcga
     9541 gccggatgaa agtcagcggc aggcgctggt gcgtgagtta cgcgaagaac tgggcatcga
     9601 agcaactgtg ggtgaatatg ttgccagcca tcagcgagaa gtttcggggc ggattatcca
     9661 tcttcatgcc tggcacgtac ccgacttcca cgggacgtta caggcacatg aacatcaggc
     9721 gctggtctgg tgctcacctg aagaggcgct gcaatatccg ctggcccctg ctgacattcc
     9781 attattagag gcgtttatgg ctttacgcgc cgccagacca gaggattagt gctaagggtt
     9841 ttgtcatcac gctggcattg cagcagtatt ccttcggctt taattaccgc cccttcagaa
     9901 taattttgat cctgataaac gcagcactga gtacagggct gcgctgactg cccgcctgaa
     9961 ctgaacactt ctggcggtac gtttacctcc acgtccggac gataatgcgg gttagccagt
    10021 gcaattaatg gaaatgctaa tactacggcg aacaatgctc gactcacagg gaactcctta
    10081 acgttattgt ctctgctact gataacggta gccgggtggc aaaactttag cgtctgagtt
    10141 atcgcatttg gttatgagat tactctcgtt attaatttgc tttcctgggt catttttttc
    10201 ttgcttaccg tcacattctt gatggtatag tcgaaaactg caaaagcaca tgacataaac
    10261 aacataagca caatcgtatt aatatataag ggttttatat ctatggatca gacatattct
    10321 ctggagtcat tcctcaacca tgtccaaaag cgcgacccga atcaaaccga gttcgcgcaa
    10381 gccgttcgtg aagtaatgac cacactctgg ccttttcttg aacaaaatcc aaaatatcgc
    10441 cagatgtcat tactggagcg tctggttgaa ccggagcgcg tgatccagtt tcgcgtggta
    10501 tgggttgatg atcgcaacca gatacaggtc aaccgtgcat ggcgtgtgca gttcagctct
    10561 gccatcggcc cgtacaaagg cggtatgcgc ttccatccgt cagttaacct ttccattctc
    10621 aaattcctcg gctttgaaca aaccttcaaa aatgccctga ctactctgcc gatgggcggt
    10681 ggtaaaggcg gcagcgattt cgatccgaaa ggaaaaagcg aaggtgaagt gatgcgtttt
    10741 tgccaggcgc tgatgactga actgtatcgc cacctgggcg cggataccga cgttccggca
    10801 ggtgatatcg gggttggtgg tcgtgaagtc ggctttatgg cggggatgat gaaaaagctc
    10861 tccaacaata ccgcctgcgt cttcaccggt aagggccttt catttggcgg cagtcttatt
    10921 cgcccggaag ctaccggcta cggtctggtt tatttcacag aagcaatgct aaaacgccac
    10981 ggtatgggtt ttgaagggat gcgcgtttcc gtttctggct ccggcaacgt cgcccagtac
    11041 gctatcgaaa aagcgatgga atttggtgct cgtgtgatca ctgcgtcaga ctccagcggc
    11101 actgtagttg atgaaagcgg attcacgaaa gagaaactgg cacgtcttat cgaaatcaaa
    11161 gccagccgcg atggtcgagt ggcagattac gccaaagaat ttggtctggt ctatctcgaa
    11221 ggccaacagc cgtggtctct accggttgat atcgccctgc cttgcgccac ccagaatgaa
    11281 ctggatgttg acgccgcgca tcagcttatc gctaatggcg ttaaagccgt cgccgaaggg
    11341 gcaaatatgc cgaccaccat cgaagcgact gaactgttcc agcaggcagg cgtactattt
    11401 gcaccgggta aagcggctaa tgctggtggc gtcgctacat cgggcctgga aatggcacaa
    11461 aacgctgcgc gcctgggctg gaaagccgag aaagttgacg cacgtttgca tcacatcatg
    11521 ctggatatcc accatgcctg tgttgagcat ggtggtgaag gtgagcaaac caactacgtg
    11581 cagggcgcga acattgccgg ttttgtgaag gttgccgatg cgatgctggc gcagggtgtg
    11641 atttaagttg taaatgcctg atggcgctac gcttatcagg cctacaaatg ggcacaattc
    11701 attgcagtta cgctctaatg taggccgggc aagcgcagcg cccccggcaa aatttcaggc
    11761 gtttatgagt atttaacgga tgatgctccc cacggaacat ttcttatggg ccaacggcat
    11821 ttcttactgt agtgctccca aaactgcttg tcgtaacgat aacacgcttc aagttcagca
    11881 tccgttaact ttctgcgata gcagcagata tgccagtaaa gaaatcccat ttgactattt
    11941 ttttgataat cttcttcgct ttcgaacaac tcgtgcgcct ttcgagaagc aagcattata
    12001 taatgccagg ccagttcttc ttcaattgtc ccgttttgaa aagctgtgct tgatatcgag
    12061 atcatccatg ataattccgc cgcccatatt agcttcgccg aggatttacc ggagctatga
    12121 ttagcgcaat cagagatata gtctgaggga aaaacagcaa atttattcaa caaggcgata
    12181 acctgctctg gggcttcctc catgtttgct ttaaaggtat tggctccatg gtcgccagaa
    12241 agaaaatgct ccattaaggc acaataactt tcgctatctt cgatacccca ttgatcctct
    12301 aaagactcgc gtcttttact tatgatatcg atcgagtcaa aaggaagcac atgatattgg
    12361 aaggtatctt tgccaggttc aggctttcgc ggccagaact ccagcgtttc agaccattgc
    12421 ttatgataga atcgataagg tgcgatcaat tgtagcgcct gtaacttctc gatactgagc
    12481 ggctcaatac ctttagcctg ataataatgc agttgttctt tttttgcttt aaaaccggcc
    12541 cgaacaataa gccccatcat aattaataga taaagaaaag agcatcccgc ggtaatcagg
    12601 cctctttcat tcaaaccgtt ggatgttatc gctgcgaaca caaacattac agcgacaaca
    12661 catgttaaat aaaaccccca cttacaaagc agcatggcct tattttcttt aatcatccgt
    12721 tcaaaattac tattaaatat ttcccagcca ttaaaagaat acttctcgct cccaggatgg
    12781 ttttgtaata aaactttttt catcacattc cctgttatta catactttag aggcgataat
    12841 tttatccatg caaaaaaaat atccaacgaa ttttcttgat ccgctggata tttcagaata
    12901 tgactcgaat agcacgaaag attcactcgc ttacgctatc gccccgcttc cgacttcatc
    12961 tgctggcgga ctttttttcg cactacgttt acgcggtgca gcctttttct tatcagcact
    13021 gccaccactg cccggagcca caatgccgcg aaactgccgc accggcgtac gtttggcttg
    13081 atcaataagc tgatatagcg tccccaccag cggctgcata aagtcctgat agcgacactg
    13141 cttttcgctg atttgcgtca gcaccgattc ccagtgcgcg gtcatgtccg gtcgcgtcgc
    13201 catctccggc agcgaatgga atagcgcttt tccggcgtcg gtggagtgga tatagcgccc
    13261 ttttttggtc aggaaaccac gcttgaacaa cagttcaata atcccggcac gcgttgcctc
    13321 tgtccccaga ccatcggtcg cacggaggat ctttttcaga tctttatcct gcacaaagcg
    13381 cgcgatcccg gtcatcgccg aaagcagtgt tgcatcggta aaatggcgcg gcggctgggt
    13441 ttgccgctct accacttcac ctttttcaca cagcaactca tcgcctttcg ccaccacagg
    13501 cagtggcgtg ccgtcgtttt cttcatcgcg ctctttgctg cctaacagcg tgcgccagcc
    13561 tgcttcagca agaaaacgcg ctttagcgac aaatttgcct ttggcaatgt ccagttcgat
    13621 aacacacttg cggaacaccg catccgggca gaattgcatc agatactgac gggcaatcag
    13681 gttatagacc ttcgcttcgt tctccgtcag gttgatcgca gaactccgtg cggtcggaat
    13741 gatggcgtgg tgcgcatcga cctttttgtc atcccaacag cggttgcgta tatctggatc
    13801 taccactggc tgcggcaaca gatccggtgc atgaacactg atggcattca tcaccgcgtg
    13861 gcgtccggca aaatgttctt ctggcaaata gcgacaatca gaacgcggat aagtgattag
    13921 cttgtgcgtt tcgtacagtt tctggcagat atcaagcacg ttctgcgcac tcagaccaaa
    13981 acgttttgcc gcttcaatct gcaacgctga aagcgaaaaa ggcagcggcg cggattctga
    14041 ttcccgttta tcgttatagc tggtgacaat agccggttga ccactaatgc ggttaaccac
    14101 atgctccgcc agtggacgat gtaacaagcg cccttcttca tcctggtacg gttcacacgc
    14161 ttcgctcggt tgccagatag cggtaaaccg ctcatcggca ggtgtcacga tatgtgcttt
    14221 gacttcaaag aagtctttcg ccacgaagtt ttcaatctct tcatcgcggc gcaccaccag
    14281 cccaagcacg ggcgtctgca cgcgtcccac ggaaagtacg ccctgataac cggcattgcg
    14341 accgagaatg gtatacgcac gggtcatatt gatgccgtac agccagtcgg cacgcgctcg
    14401 cgccagcgca gaaacgcaca gcggtacaaa ctcactgttg gaacgaagac ggtcgatcgc
    14461 ccgctcaacc gcctgcgggt tcaggtcgtt tatcaagcaa cgctgtacct gctggcgctt
    14521 ttccggtgcc agttgcagat agtccagcac ttcatccacc agcaattgcc cttcacgatc
    14581 cgggtccccg gcgtgaacga tttcgctggc ttcatgcagg aaccgtttga tgacgttaag
    14641 ttgtttggtc acggagggtc ggggctgtaa ttgccacttt tccgggacaa tcggcaaatc
    14701 cgcaagattc cagcgcgcat agcggctgtc gtaggcgtct ggctgcgcct gctcaagcag
    14761 gtgaccgata caccaggtca ccacctgacc attaccgcac tcgataaagc catcgccttt
    14821 ccggtgcggt ttgggcagga catcagcaat ggcgcgcgcc agactcggtt tttcggcaat
    14881 aaacaaccgc attgaattaa cgaatctcaa ccatggcacg accgccgcgc gctggcacca
    14941 gttcgccaat tgccgtcagt tcaatgccaa actcggcggc tgtagctttg acctcatttt
    15001 ctgcttccgg catgaccgcc agcagcaaac cgccagaagt ttgcggatca cacagcagat
    15061 cgcgcacttc acgcggcatt tcacccatca gatgaccgta gctggcaaag ttacgttcag
    15121 tgccgccagg tactgcgccc aacttaatgt actcttcaac accggggagt ttcgggatcg
    15181 cttcatagtc gacgcgtgcc tgcacaccag ccccctgaca catttcgctc aagtggccca
    15241 gcagaccaaa gcccgtaacg tcggtcatcg cttttacgcc ttcgatgttg gcaaaggacg
    15301 cgcctgcgat gttcatccgg cacatcactt ccgtcgccag tccctgatgt tctggtttca
    15361 acagtgattt tttctcagcc gtggtaagaa cgccgatccc cagcggtttc gtcaggaaca
    15421 gtttgcatcc ggcttgtgcg gtactgtttt tcttcacccg ctcggtcggt acgatccccg
    15481 ttaccgccag accaaaaatc ggctccggcg catcgatgga gtgaccgcca gccagcgcaa
    15541 tacccgcctg acgacatgca tagcgtccac cttcggtcac ttcgcgggca atttctgggg
    15601 aaagtttgtt aatcggccag ccgaggatcg caatcgccat aatcggtttg ccccccatcg
    15661 cgaagatatc gctgatggcg ttagtcgccg caatgcggcc aaaatcgaaa ggattatcaa
    15721 cgatcggcat aaagaagtcg gtggtactga taacgctggt gccattgccc agatcgtaca
    15781 ccgccgcatc gtcgcgggtt tcattaccca caagcaaatt cggatcaaca aacttcgcct
    15841 gctcactatg caggatggtt tccaacactt ttggggaaat tttacagccg caaccagctc
    15901 cgtggctgta ttgggtcaaa cgaatcgagt tctcgctcat ggacatctcc tgtcaatgca
    15961 atccgggtat ggtaaccctc attccgtgaa gtgataagtg agagtgtctg aattcctgcg
    16021 cctttgctca caatccagac agtttcgcga caattatcag aaataagtta caaacggcgt
    16081 cgggtccggg acgttaatcg acgtagatgc tttcagctgc ggcgtaccga ggtagagaaa
    16141 accgacaatt ttatcctgct cacggcaacc gaatgcttca cgcactaccg gactttcagt
    16201 taatgcgcca ctgcgccaga tgccgccaaa cccctgggca actgctgcca tttgcatcgc
    16261 catgaccgcg catccggcag acatttcctg ttcccagcgc gggactttat gattctcttc
    16321 gcatttcgcc accaccgtga tgatgagcgg tgcgcggaac ggcgcattac gggctttgtc
    16381 gatagctttg tcatcactac cggcagcaat cgccccctgt tccagtacgg cgctgaaacg
    16441 ctcgcgccct tccccttcaa tcacaaaaaa atgccacggt tgcatggact tatggtccgg
    16501 cgcacgcata cccgcacgca ggatgttttg cagttgttca cccgttggcg cgggttcagc
    16561 caagcgggag gcgctacggc gattgatcaa tagttcgagt gcatccattt gattaactcc
    16621 tgtcgtgata tttattcaca aaattaacac gagagtggat tttgttacag cacagtccgc
    16681 aattcctgct gacaagtacc ggttgggtca ttacgataac cacatctatt gcgcctgtga
    16741 caggtgtgac cttaagttgg gagaatacat gcgaaccctt tggcgattta ttgccggatt
    16801 ttttaaatgg acgtggcgtc tgctgaattt cgtccgtgaa atggtactta acctgttctt
    16861 tattttcctc gtactggttg gtgtggggat ttggatgcag gtcagtggtg gtgattcgaa
    16921 agaaacggcc agtcgtggcg cactgctgct ggacatttct ggtgtgatcg tcgataaacc
    16981 cgacagttct cagcggttta gtaaattaag ccgccagctg cttggtgcca gttccgatcg
    17041 tctgcaggaa aactcactgt ttgatatcgt caacactatt cgccaggcga aggacgaccg
    17101 caatatcacc ggtattgtga tggatctgaa aaacttcgca ggcggcgacc aaccgtctat
    17161 gcagtacatc ggcaaagctc tgaaagagtt tcgtgacagc gggaaaccgg tttatgccgt
    17221 tggcgagaac tacagccagg ggcaatatta tctcgccagt ttcgccaata aaatttggct
    17281 gtctccgcaa ggcgtggttg atctgcacgg ctttgccacc aacggtctgt actacaaatc
    17341 gttgctggat aagctgaaag tttccaccca tgtgttccgc gtgggtacgt ataaatctgc
    17401 cgttgaaccg tttattcgtg atgatatgtc accggcagcc cgcgaagctg acagccgctg
    17461 gattggtgag ctgtggcaaa actatctgaa tactgttgcc gctaaccggc agatccctgc
    17521 tgagcaggta ttccctggcg cgcaagggtt gcttgagggt ttaaccaaaa ccggtggcga
    17581 taccgcgaaa tatgcactgg aaaacaagct ggtcgatgca ctggcatcga gtgcggaaat
    17641 cgaaaaagca ctgaccaaag aattcggctg gagtaagact gataaaaatt atcgcgccat
    17701 cagttattac gattacgcat tgaaaacgcc ggcagatacc ggtgacagca tcggtgtcgt
    17761 ctttgctaat ggcgcaatta tggatggcga ggaaactcag gggaatgttg gcggtgatac
    17821 cactgcggca caaatccgcg acgctcgcct tgacccgaaa gtgaaagcga ttgtcctgcg
    17881 tgttaatagc ccaggcggca gcgttaccgc gtctgaagtg attcgcgctg aactggcagc
    17941 agcccgggca gcgggtaagc ctgtggttgt atcgatgggc ggcatggcgg catctggtgg
    18001 ttactggatt tccacgccag ctaattacat tgtggctaac cccagcaccc tgaccggttc
    18061 tatcggtatc ttcggcgtga tcaccaccgt agaaaatagt ctggattcga ttggtgttca
    18121 tactgatggt gtctcaactt caccgctggc ggatgtttct atcaccaggg cactgccgcc
    18181 ggaagcgcag ctgatgatgc agttaagcat tgagaatggc tataaacgct ttatcacgct
    18241 ggttgctgat gcgcgtcatt cgacgccgga gcagattgat aaaattgccc agggccacgt
    18301 ctggaccggt caggatgcaa aagctaacgg gctggtcgat agtctcgggg atttcgatga
    18361 tgcggtcgcc aaagcagcag agctggcaaa agtgaaacag tggcatctgg aatattacgt
    18421 tgatgaaccg accttcttcg acaaagtgat ggacaacatg tctggttctg tccgggcaat
    18481 gttgccagat gcgttccagg ccatgttacc tgcaccgctg gcctcggtag cctctaccgt
    18541 taaaagtgaa agtgacaagc tggccgcgtt taatgaccca caaaaccgtt atgcgttttg
    18601 cctgacctgc gccaacatgc gttaagtctt gtactgagtg gccgacagat cgtcggccac
    18661 attatttttt acgtcgacga atcctcttcc cgctgtttcg ccccatattt ccttatccgc
    18721 atagtatcag gtgcgctccc cctgcctcac gtatatactt ttgctctttc gatatcattc
    18781 atatcaatat catgcaaaag aaatcaattt acgttgccta cacgggcggg accatcggga
    18841 tgcagcgttc cgagcagggt tatataccgg tgtcaggtca tctacaacgc caactggcgc
    18901 tgatgccgga attccatcgc ccggagatgc cagatttcac cattcatgaa tatacgccgc
    18961 tgatggattc ttcagatatg acgccggaag actggcagca tattgctgaa gatattaaag
    19021 cgcactatga cgactatgat ggttttgtca ttctgcacgg caccgacacg atggcgtata
    19081 ccgcctctgc gctgtcgttc atgctcgaga atctcggtaa accggtcatt gtgacagggt
    19141 cacaaatccc gctggctgag ttacgctctg acggacaaat taatctgctg aatgcgttgt
    19201 acgttgcggc gaattatccg atcaacgaag taacgctctt tttcaataac cgattgtatc
    19261 gcggcaaccg cactaccaaa gcccatgccg atggttttga tgcgtttgcc tctccaaacc
    19321 ttcctccgtt actggaagca ggtatccata ttcgtcgttt gaatacgcca cccgccccgc
    19381 acggtgaagg ggaattaatc gttcatccaa tcaccccaca accaattggc gtagtgacga
    19441 tttatccagg gatttctgct gacgtcgtgc gcaattttct gcgccaaccg gtgaaagcat
    19501 tgattctgcg ctcctatggc gtgggtaatg cgccacaaaa caaagccttc ctgcaggaat
    19561 tacaagaagc cagcgatcgc ggtattgtgg tggtcaacct gacacaatgt atgtccggta
    19621 aagtgaacat gggtggttat gccaccggta acgccctcgc ccatgccggc gtaattggcg
    19681 gtgcagatat gactgtagaa gccacgctaa ccaaactgca ttacctgctt agccaggaac
    19741 tggatactga aaccattcgc aaggccatga gccaaaacct gcgcggcgaa ctgacgccgg
    19801 atgattaagg agactgtaat gccccctcgc gccctgttac tggtcgattt acaaaatgat
    19861 ttctgtgctg gtggcgcgct cgccgtgccg gaaggtgaca gtacggtgga tgtcgctaac
    19921 cgcctgattg actggtgcca gtcgcgcggt gaagcggtta tcgccagtca ggactggcac
    19981 ccggcgaatc acggcagttt tgccagtcag cacggtgtag agccttatac gccaggccaa
    20041 ctcgacggtt tgccacaaac cttctggcca gatcactgtg tgcagaacag tgaaggcgca
    20101 caattacatc cgttactgca ccaaaaagcg atcgcagcgg tgttccataa aggcgaaaat
    20161 cctttagttg acagttacag tgcctttttt gataacggcc gtcggcagaa aacctctctc
    20221 gatgactggt tacgcgatca tgaaatcgat gaattgatcg ttatgggcct ggctactgac
    20281 tattgcgtga agtttaccgt gctggacgcg ttacagttag gttataaggt aaacgtgatt
    20341 accgatggtt gtcgtggcgt gaatatccag ccccaggaca gtgcgcacgc gtttatggag
    20401 atgtcagcag ctggggcaac gctatatacg ctggcagact gggaagagac acaggggtaa
    20461 ttttacgctg gcctacaatt ctgtactggc attgtaggcc aaataaaaca cgtcagtggc
    20521 acatctggca attgatgcca tcaacgaaag atttaattca cctcagaaat ctcttccaac
    20581 gacaccttcc gcgtttcgat gccaaaaatg gagagaacca gcgcacagag caataacatg
    20641 acaccaagta ccataaacac cgtgatcgac ccataatgtg ttaataatgc cgcaacgcca
    20701 tagggcgtga agactgcgac gatccgtccg acggcattaa cgaaacccga accgcgcagg
    20761 cgtaaatgcg ttggccaaag ctccgggata taaaccgccg acgcgaagca aacatacatg
    20821 tataaaaaga agatcatcac cagtccatag attaaaatcg cccactctgt agtctgaatt
    20881 gaatagatat agcctaacac ggcaataata ataagtaagg tggagccaaa taaccgacga
    20941 ggaaaatgat caataattaa tgccgcaata aatattccta ccggagcgcc aatcataata
    21001 acagcggtca ttaatattga tttatcgaca tcaatgccgg agttaacaaa tatggtcggt
    21061 atccatacgg tgatggtata aagcgaaatg ttcattgcaa ttaaaacagt aatcgcgact
    21121 aatgtacgtc gtaacatttc acctttaaac aggagccaga aagtaccctt gattacttta
    21181 accttgctgt tgctctgata cgaagtaagc gggggtaaac gaatactctt ctctctttca
    21241 atttgctgct ctacttcacg aagttggcat tctgcacctg cgatttgccc tttccctgcc
    21301 agccatcgtg gcgactcgat aaagtattta cctgagagaa accaggctaa cagtatgcca
    21361 ataccaccca gcagaaacat tattcgccaa ctaaaaaaag cgataaccac cacgcctatc
    21421 gccgcagaca gcatgggcga ccagttacca acaaatgaga gccgcgcgga ccattttcca
    21481 cgcaccgtcg cggggataaa ctccgtaaat gaggcatagc caaccataat cagcgccccc
    21541 attcctgttc ccatcaggaa gcgaaagaag atgagccagt acatatcagg gacaaaagcg
    21601 gcccctgttg cagcaatacc gacgatgaga agatttatgc gaaacgccct gcgccgccca
    21661 aagtagtcac caataaaccc accagtaagt gagccgatga aataaccaaa cattaatgcc
    21721 gaggtaaagg cggcattgag gaaattattt gaccatccat tgcttaccag ctttgctaag
    21781 acgacattac cggagtaact caaaaaccct gttaataaca gactaaagct tataatacca
    21841 aatatacgat aatgaaaccg ggccaaaggc aagcggtcca gtcttgcgcc aatttgatca
    21901 tattgttcca ttaggtgcct cggatttgct aaaaaggtag caattgcggc aaattcactt
    21961 gccgcatctt tatcatcatt ttatttcaag gcgcaggaac aaataatatt gacaacgtgt
    22021 gcttaaatta ccacaccagc tggatattat tgtctttgca aaatgctatc cactctgcac
    22081 ccggtgattt at
//
LOCUS       DAPOAV010000076        21824 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.076, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000076 DAPOAV010000000
VERSION     DAPOAV010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21824
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.076"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..476
                     /locus_tag="RN951_003261"
     CDS             <1..476
                     /locus_tag="RN951_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008502231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDX2528221.1"
                     /translation="EEHISGSVAASERPGFIRLLDRMENGDVLIVTKLDRLGRNAMDI
                     RKTVEQLAALDIRVHCLALGGVDLTSPAGKMTMQVISAVAEFERDLLLERTYSGIARA
                     KAAGKRFGRPPILSEEQKQTVTERLNAGISISAIAREFNTTRQTILRVKAGLLQE"
     gene            661..1218
                     /locus_tag="RN951_003262"
     CDS             661..1218
                     /locus_tag="RN951_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HDX2528222.1"
                     /translation="MSTTVKPSADAAAIHNTREAVRSQPGLGNLTFQMKARSSGGLTV
                     RTETGATIQNGVIDTSRVGKFSNIGDEPAGLLGTDTGMSPTEYIMQALAGCYTATLTM
                     MAAEKGIDLDGIELDLNFDINLNGFLGLDSNVRKGAKSIRVDVHLTSKTASREELEAL
                     VSEMQKNSPIHDTLANPVEMITRLA"
     gene            1360..1941
                     /locus_tag="RN951_003263"
     CDS             1360..1941
                     /locus_tag="RN951_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008502230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDX2528223.1"
                     /translation="MTTMTRERLLSEAEHLMREKGYSAFSYADLSKIVGITKASIHHH
                     FPTKDILGEQVVIQAFSDTQRVFEQIEATEKSAERRIAAYIDIFAQSHKASLLPLCCA
                     LSAETANLPQAITVQTSLYFDMQIEWLTKVVRAGMESGEFSSHAEPSDIALMIINVCE
                     GSSVVAHATARPEVFANSLKYIKLLLNTPHSGE"
     gene            1946..2284
                     /locus_tag="RN951_003264"
     CDS             1946..2284
                     /locus_tag="RN951_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016246488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HDX2528224.1"
                     /translation="MLDWNNYRSELMQRLGELGKLTPETMKGVVALGNAGNKTDLLGA
                     KVRELIALACAVTTRCDGCIAFHADAAVKAGATDAEIAEALGVAINLNAGAAVIYSAR
                     TLDAVGQARG"
     gene            complement(2314..2643)
                     /locus_tag="RN951_003265"
     CDS             complement(2314..2643)
                     /locus_tag="RN951_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002431133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDX2528225.1"
                     /translation="MRTLTAYNEDNFRQIEQYKGISVVRFSAPWCPPCQASEEMFSQF
                     ADRLDRDIQVGKVNVDQAPVLTTKYEIWGLPSVLIFHEGQLVKRIPGVKPASVYAQAI
                     ADIKKGQ"
     gene            2857..3963
                     /locus_tag="RN951_003266"
     CDS             2857..3963
                     /locus_tag="RN951_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkene reductase"
                     /protein_id="HDX2528226.1"
                     /translation="MSKLFTPYNLSGLALKNRVVMAPMTRTRTMNEVPDEVVALYYAQ
                     RASAGLLITEGMPVSEEGRGYLYTPGIYNDEHVQGWRKVTQAVHAKGGRIFAQLWHVG
                     RMSHVSLQPGHIAPVSAGTVQAVNTTVFALTESGEPGPVVPSQPRALETHEVKRITAD
                     FVHSARLAMEAGFDGVEIMAANGFIFDQFLSSELNTRTDEYGGSVENRQRFLLETIDA
                     VAEAVGNSHVAVRLSPFGRIYDLAPYEGEEQTWSAITDALGQRELAYVHLYYQPVYTK
                     APLPEGFRRRFRNTFKGTIIAAGGFTRDIAEQALEDDELDLVAFGVPYIANPDLVERM
                     QNGWPLAESDRATYYGVSGSPEKGYTDYPVWQAQ"
     gene            4029..4730
                     /locus_tag="RN951_003267"
     CDS             4029..4730
                     /locus_tag="RN951_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family oxidoreductase"
                     /protein_id="HDX2528227.1"
                     /translation="MQTLKHTLTIDIWSDLVCPWCWIAKKRFEQGLNRFEFRDQVVIR
                     HHSYRLAGGTPAMPFKDAIVKKLGSQHSAELMMDQVGTAGKSEGLIYNFDGMMFGDTE
                     DAHTLLVAARKAGIADAVEERFYHGSITEGRSLFDRQQLVAMAVEAGMEKADAEAALE
                     NDDFRATVSDDEAHAQSIGLSGVPVFVMNEKYAISGAQGADNFLNALRQVWDEQQTEF
                     SATAGQTCGTDGCSI"
     gene            4796..5569
                     /locus_tag="RN951_003268"
     CDS             4796..5569
                     /locus_tag="RN951_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016240531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDX2528228.1"
                     /translation="MNTFFKGKKLLVVGGTSGMGLAVARMVLEAGGSVVLTGNKKDKA
                     EAVQKELGPLGPVAVIAANLMTEEGMETIRHEINASHRDISLMVNAAGIFMPKGFTEH
                     SFADYDMYFSLNRATFFITQDVVKNMLAAKLEGSIVNVGSIGAQAALGDSPSSAYSMA
                     KAGLHALTRNLAIELASAGIRVNAVSPGIVHTPIYEGFMDKADIADAMKSLNDFHPLG
                     RVGTAEDVANTILFLLSDKTSWVTGAIWDVDAGIMAVRR"
     gene            complement(5755..6978)
                     /locus_tag="RN951_003269"
     CDS             complement(5755..6978)
                     /locus_tag="RN951_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDX2528229.1"
                     /translation="MKYDFDEYVSREKTDSLTVDGWREYLFAGQSEFAMRYPAEGLIN
                     LWVADMAFATPEPILQAIRDRLDRKILGYTKIYDEEYYEIFGNWCERQYGHRFKTEDI
                     VLSPGIIPALNRLVPLLTDKDDSILIMTPSYGPFKKAGEYSQRRVVYSALKKSAGGWE
                     PDWEDFTRKASQADLRVKILFLCNPHNPTGRVWRPDELKRIIEICLANDIWVISDEIH
                     CDLSRSGIGHTPAASLFPDSTRIITCMSSSKTFNLAGNLLANIIIPDPGVRSEWRLRH
                     DEFISPLSLAANKAAWSECDDWLVHLREYIDGNFQYLHDYLKSYLPETRFSIPEGTYL
                     AWIDISHYLPDTVGEDLSLYFARESGVLLEGGLLFVDNGEGHIRLNLACPRTMLTAGM
                     KRISQVLRTPAPNRV"
     gene            complement(7109..7981)
                     /locus_tag="RN951_003270"
     CDS             complement(7109..7981)
                     /locus_tag="RN951_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDX2528230.1"
                     /translation="MARCALILKISLAMLAFAANSILCRLALQGGHIDPLSFSSLRLA
                     SGAFVLSPFLFYHARTTLSLWRPLSGFYLMAYAVLFSVAYIHLDTGAGALLLFGAVQF
                     AMVIHGLFKGESLSAMRACGLVLALTGIAALLLPGTKAPPLYSALMMIVSGLAWAAYS
                     VRGRAGQAAGASTAANFILAAPMALALTLLFMKQGHSDAAGIALSLLSGAVASAGAYV
                     LWYTLLPSLGSITASILQLSVPCLAMLGGVVFLGESLTVRTIFSALAVLTGIVMVTRE
                     KSPRQPMAKARKPQ"
     gene            8223..8975
                     /locus_tag="RN951_003271"
     CDS             8223..8975
                     /locus_tag="RN951_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000734115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDX2528231.1"
                     /translation="MKKLKFTFKNAAGEELAGLLELPENPKAFALLAHCFTCGKDLKG
                     AARIARKLTEKAIAVLRFDFTGLGNSEGDFSNTNFSSNISDLLCAVDYLRRQYEAPSL
                     LIGHSLGGSAILSIAGEVPEAKAIVTIGSPGELTHVKRLFKDDVENINQHGAYPVELA
                     GRVFTLKKQMLDNIQEHKIAHKVFAMNKPLLIFHATEDDTVLIEQAEKIFKAAKHPKS
                     FISLGKADHLLTHAQDAEYVADIIISWSECYL"
     gene            9002..9315
                     /locus_tag="RN951_003272"
                     /pseudo
     CDS             9002..9315
                     /locus_tag="RN951_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016495564.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            9415..10419
                     /locus_tag="RN951_003273"
     CDS             9415..10419
                     /locus_tag="RN951_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110-like element IS4321 family transposase"
                     /protein_id="HDX2528232.1"
                     /translation="MENIALIGIDLGKNSFHIHCQDRRGKAVYRKKFTRPKLIEFLAT
                     CPATTIAMEACGGSHFMARKLEELGHSPKLISPQFVRPFVKSNKNDFVDAEAICEAAS
                     RPSMRFVQPRTESQQAMRALHRVRESLVQDKVKTTNQMHAFLLEFGISVPRGAAVISR
                     LSTILEDSSLPLYLSQLLLKLQQHYHYLVEQIKDLESQLKRKLDEDEVGQRLLSIPCV
                     GTLTASTISTEIGDGKQYASSRDFAAATGLVPRQYSTGGRTTLLGISKRGNKKIRTLL
                     VQCARVFIQKLEHQSGKLADWVRDLLCRKSNFVVTCALANKLARIAWALTARQQTYVA
                     "
     gene            10697..10801
                     /locus_tag="RN951_003274"
                     /pseudo
     CDS             10697..10801
                     /locus_tag="RN951_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000019445.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(10951..11583)
                     /locus_tag="RN951_003275"
                     /pseudo
     CDS             complement(10951..11583)
                     /locus_tag="RN951_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309185.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="histidine-type phosphatase"
     gene            complement(11705..12190)
                     /locus_tag="RN951_003276"
     CDS             complement(11705..12190)
                     /locus_tag="RN951_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528233.1"
                     /translation="MAFIWNDESLAILRENAGILTTEQIAQLLHTNITAVRNMAYRLK
                     LSLRVTAYNHRRIAQVQALYASETLSLKEIAAKTGLTASTVQYIVYVKSKNKPYATTE
                     YVSFETENAVHYRVQKEFVDTERSLLDNISDNTRFRELYLTDGTFYCARNIKYEVFIS
                     E"
     gene            complement(12215..12700)
                     /locus_tag="RN951_003277"
     CDS             complement(12215..12700)
                     /locus_tag="RN951_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HDX2528234.1"
                     /translation="MRWHNVLLLAAAILISGCKEEKLAVGAPAPALAAFDLQGQESGL
                     ERWQGKAVYLNFWSAGCGGCLAEMDTLEALSKKWGDKVVVVAVNTDPETVRINDLLAK
                     HQITYPVVRDQLNITQERYQVIGTPTSVLIDSEGRVLELHQGMRKPSELEATFARLAA
                     R"
     gene            complement(12687..13382)
                     /locus_tag="RN951_003278"
     CDS             complement(12687..13382)
                     /locus_tag="RN951_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004863043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX2528235.1"
                     /translation="MSVTHIPQVAIETRHLYKRFGDVTALDDINLRIAQGEFVAIMGA
                     SGSGKTTLMNILTCLDTATEGQVFLDGTDAAALDEEGRRRFRAEKIGLVFQQFHLIPF
                     LTALENIMLAQHYHSVVDEAAARKVLEQVGLGHRVTHLPSQLSGGEQQRVCIARALVN
                     EPPVIFADEPTGNLDEENEQRVLDLLTDLHRQGRTIVMVTHNPALGQFADRILRLQHG
                     KYLGEEANQHALA"
     gene            complement(13387..14517)
                     /locus_tag="RN951_003279"
     CDS             complement(13387..14517)
                     /locus_tag="RN951_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX2528236.1"
                     /translation="MAAKRTMLWLLVWRALRLRFQRVSVVFAALMVGATIVTALSAVW
                     FDINTKMSEELRTFGANFYIGPGHGSSMPQQELQSILDQAPQGLVHGASPWLYGMART
                     ELEKVVMVGVWFESLQKLVPYWQVTGSWIGVSFDDRNAMIGVKLAERLNVQPGDSITL
                     VDHNQRKNLQIKGIVESGDATDNMLIVSLDVAQAWLHQPGKISHGLLSVSNDVGQVEN
                     YASRLQAQYPDLEIRPVRKVSASEGQVLDKIKGLMGLVSIVILALSSLCVNTTLMAIV
                     GERAREFALQKALGSSNGDIVRQILLETSIIALAAVACGWVLGYLLAQLLGLTVFNAA
                     ISLRLPVLPITLVLSLLVAILAAIVPVRRAVSVEPAKVLKGE"
     gene            complement(14507..15790)
                     /locus_tag="RN951_003280"
     CDS             complement(14507..15790)
                     /locus_tag="RN951_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011906231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX2528237.1"
                     /translation="MLWRMLRQSWGRNLRRKVLAIITVFLASSLISALLAVSIDIGDK
                     MSRELKSYGANILIEPAGQAALPALFSESSNPLSGQDFLDEAELPNIKDIFWRNNIVG
                     FAPMLGGEASVEGEPVRILGTFFSQPVDIPDEEGYETGQKTVSPYWQVTGDWPQEPAG
                     AEPQTLVGHALARQMGWKPGDKLTLRTEGEAVQVTVSGILSSGGDEDNQLVMPLSTVQ
                     HLLGLPGKVQAIRVSALTVPENELSRRARENLDALNAEEYDLWYCTAYVSSIAHQLEE
                     AISGAEVRPVWQVAASEGVVIDKIQLLMAVVTVAALVASAMGIASLMTSTIMERAKEI
                     GLMKALGARQWQIMLLFYLEAASSGLAGGALGCIAGWGLAKAIGVMLFDAPLNFAWIV
                     VPCVLVIAVLIALIGTWFPARRIARLYPVEVLYGR"
     gene            complement(15793..17172)
                     /locus_tag="RN951_003281"
     CDS             complement(15793..17172)
                     /locus_tag="RN951_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003836820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2318 domain-containing protein"
                     /protein_id="HDX2528238.1"
                     /translation="MSYFFVTTLQVFFCIALLSGVLWSRNDPPSLRPLTWTLLTGLIA
                     GVLAGLFIHGSQPVQLLLVGAEVMVSLLFVLSFWWASTRIRYLWQGILIFGAARHWAL
                     DPNLGGLTSTHVLNTDLLLNLTAVVLAFAILCLAGVLCAMLLRRIRGLYWPLTLILLV
                     MIWLPLSGNLLLLLMKLQVVPLGKSLLSFVAKVTNNTALYNWAGAALLLALALCWLPA
                     LLRAFRQTRETEEPIAHRLALAQRRNALRLWLVTIGCAVVVIAGQLWWDKVASQPPQL
                     SEAVPVTLGSDGMVRLPVEQLRDGKLHRFVWVADDGKAVRFFVINRYPDKLRFGVVFD
                     ACLLCGDQGYVMEGNQVICVACGVHIFIPSIGKAGGCNPVPIENWHNDEKELVIPGKE
                     LATGVNYFSTVMTIKVTDPVDGSTLTNTSADYKYSYGGKTWFFSSEANYERFRETPEQ
                     FVPADMREE"
     gene            complement(17276..17803)
                     /locus_tag="RN951_003282"
     CDS             complement(17276..17803)
                     /locus_tag="RN951_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016674077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron transporter"
                     /protein_id="HDX2528239.1"
                     /translation="MTMKKTLIASAVMASIFIAPAAFAFKEYPAGEPVTMNEMELAAV
                     YLQPIDMEPRGMGLPAAKADVHLEADIHAVEGNKNGFGAGEWIPYLTISYTLVNNDTG
                     EKQEGTFMPMVASDGPHYGANIKMMGVGNYKVTYHIEPPSKAGMHRHTDSETGVGRWW
                     KPFDVSYEFKYVGLN"
     gene            complement(17844..19730)
                     /locus_tag="RN951_003283"
     CDS             complement(17844..19730)
                     /locus_tag="RN951_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012132915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FTR1 family iron permease"
                     /protein_id="HDX2528240.1"
                     /translation="MSVWASTNYAPLIEDIEQRLDKTAELYQQQHADEARRTVQMAYF
                     EVFENLEGPIRINISARKSYEMESAFGEIRRMIGEKKPLADVQARIDWLKAALREVEP
                     VLDGGHRLVAEEQHNALSRDDIAVHWQESFRTIDDLLAQAVTEYQAGNYSVASQHVQQ
                     AHYQGFKNSEMEMSLRQNRSAKDAASINQQFSSLIALTAQPDHLNDVSYQVTTLLQDI
                     EDILPGLPTTRDDQQVAAAQSADNIPAADEGNNRTDWAEVTTGINQSIQDAIARYQGG
                     DAKNAILDIQDTYFDRFEASGMENKIGSRDSAFKTTLEAYFTRLVSLMKAGQPVERLN
                     AEASALTQDLQKAVTMLGEGEETQWSLLLYSLMIIVREGLEALLIVAAIVAYMVKNNH
                     QDKLPLIRQSVIVALIASVITAAIFQMLFTNSGASRELLEGITMLIAVVMLFFMSYWL
                     LSKVEARHWKAWLEGKLSHSLSRGSLVGLWLTSFLAVYREGAETVLFYYALIGDANTV
                     SGHMAIGAGFVIGCVVLLLAWLVMRYSVVRLPLKPFFMFTGSFMYLMAFVFAGKGVLE
                     LVEGKLFQPTLINGFPEISWLGIYPYVETLLPQVVLLLAALVALWVMRRKSAVPGETI
                     KNNP"
     gene            complement(20077..20892)
                     /locus_tag="RN951_003284"
     CDS             complement(20077..20892)
                     /locus_tag="RN951_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014640325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+)-translocating NADH-quinone reductase
                     subunit C"
                     /protein_id="HDX2528241.1"
                     /translation="MIRSGDFFDFHFDRDNNSMRKGKIIVASMMVLCVLIFVAAAAWF
                     MLFQGEMTEPTEEEKQAAILHAAGLMKSETQDKKSVETLYHRYIIQRHVNLDSGELVA
                     GSSADTARQKCEKLAPERDPAQVRQRCTVADVFFVKDKNNEIQQVIIPVTGKGAKSMM
                     HAFLALGLDGRTVRNLYYYQQRETPFLGARVEDANWRKQWPGKRLLDNSGHPALKIVQ
                     DKPEHADEYTVDGISGATLTSTGVEKSINYWMGPQGYGQFLQRLASDRNNLNL"
     gene            complement(21075..21581)
                     /locus_tag="RN951_003285"
     CDS             complement(21075..21581)
                     /locus_tag="RN951_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003846856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein disulfide oxidoreductase"
                     /protein_id="HDX2528242.1"
                     /translation="MLSKLRRWLREGAILLVVLAGVIILLDVWRSPQMPAMFDSTPLH
                     TLDGETVTLASISEERPVLLYFWASWCGICRFTTPDVARLQSEGESVMTIALRSGNDG
                     EVSRWLSRKRVTFPVVNDSGGEISRNWEISVTPTLVVVSKGQVVTTTSGWTSYWGMKL
                     RLWRAAMF"
     gene            complement(21571..21729)
                     /locus_tag="RN951_003286"
     CDS             complement(21571..21729)
                     /locus_tag="RN951_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001351253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HDX2528243.1"
                     /translation="METLSTNLQLARLVGVQGTPATIIGDEMIPGAVSWETLEAVVKE
                     KLAVAHAQ"
BASE COUNT         5315 a         6024 c         5540 g         4945 t
ORIGIN      
        1 ttgaggagca tatcagtggc tcggttgctg ccagcgaacg ccccggattt atccggttgc
       61 tagatcgcat ggaaaatggg gatgtactga ttgtcaccaa acttgaccgt ctgggtcgta
      121 atgcgatgga tatccgaaaa acagtagagc aactggcggc tttagatatt cgcgttcatt
      181 gtctcgcact cggaggcgtt gatttgacca gtccggccgg aaaaatgact atgcaggtaa
      241 tttctgctgt agcggagttt gagcgggatt tgctgcttga gcgaacgtat tcaggtattg
      301 cgagggcaaa agcggctgga aaacgcttcg gtcgcccccc catcctgagc gaggaacaaa
      361 agcaaacagt gacagagcgc ctaaatgctg gcatcagtat cagtgctatt gcccgggaat
      421 ttaataccac ccgccagact atccttcggg taaaggctgg attgctgcaa gagtgagcgg
      481 ctgggaagat tataaaaaaa tcaaatggtt attatgaaat aaaacagcct tctgggttct
      541 tttcccccta ttttttataa aagagtagac aaaagaggtt cgcgatatta acctgccaac
      601 tagatggttg gcactgatta caccagctat aacttttatc aagaaattac aggagccatt
      661 atgtctacta ccgttaaacc ttctgcagac gcagctgcga tccacaatac ccgtgaagca
      721 gttcgcagcc agcctggcct gggtaacctg actttccaga tgaaagcccg ttccagcggc
      781 ggattaaccg ttcgcacaga gaccggcgcc acaatccaga acggcgttat cgataccagt
      841 cgcgtgggga aattttctaa tatcggtgat gaacccgcag gtttactcgg caccgatacc
      901 ggcatgagcc cgactgaata catcatgcag gcgctggctg gctgttatac cgccaccctc
      961 accatgatgg ctgctgaaaa agggatcgac ctggacggta tcgagctgga tcttaatttc
     1021 gatatcaacc tcaacggctt ccttgggctg gacagcaacg tgcgtaaagg tgcgaaatct
     1081 attcgcgtcg atgttcacct tacgagcaag accgccagtc gcgaggagtt agaagcgctg
     1141 gtcagcgaaa tgcaaaagaa ttcgccaatc cacgatactc tggctaatcc ggttgaaatg
     1201 attacacgcc tggcgtgatg tcagagatgt aatgctgcca ttcagaatgc aggatggcag
     1261 tgacgttcag ctctgcacga tactgagtca gtgatacaac ttgctacgga aaaatagcaa
     1321 taatataatc tatcaactag tagattatat ggagtgatta tgacaaccat gacacgggaa
     1381 cggctgctca gcgaagcaga acacctgatg cgcgaaaaag ggtattcagc attcagctat
     1441 gctgatttat caaaaatagt gggtatcacc aaggccagta ttcatcacca tttcccgacc
     1501 aaagatattc tgggtgagca ggtggtaata caggcgttct ctgatacaca acgcgtattt
     1561 gagcagatag aggcgactga gaaaagcgcg gagagaagaa ttgcggctta catcgatatc
     1621 ttcgcgcaaa gccataaagc ttcgctactg ccactgtgtt gtgcgttgtc agcagagacc
     1681 gccaatctgc ctcaggcaat tactgtacag acatcacttt atttcgatat gcaaatcgag
     1741 tggctcacaa aagtcgtcag ggcgggcatg gagtcaggtg agttttcatc ccatgccgaa
     1801 ccatcagata ttgctttgat gatcattaat gtctgtgaag gctcaagcgt agtggcgcat
     1861 gcaacggcca gacccgaagt cttcgccaac agccttaagt atataaaact gcttcttaat
     1921 acccctcatt caggagaatg acactatgct ggactggaac aactatcgct cagagttaat
     1981 gcaacgttta ggcgagttgg gcaaactgac ccccgagacc atgaaaggcg tggttgccct
     2041 gggcaacgca ggtaacaaaa ctgacctttt gggcgcaaaa gtgcgagaac tcattgccct
     2101 ggcgtgcgca gtcacaaccc gctgcgacgg ctgtattgct tttcacgccg acgccgctgt
     2161 gaaagccggt gcaaccgacg ctgaaattgc tgaagcgctg ggcgtggcga ttaacctcaa
     2221 cgctggcgcg gcggtcattt attcagcccg cactctggat gccgtcggtc aggcacgcgg
     2281 ttaagcatta ataaattcca tgttaaaagg gcattactgc ccttttttta tgtccgcaat
     2341 agcctgagca tataccgatg caggtttcac acccggtatg cgtttaacta attgcccttc
     2401 atgaaatatc agcacagacg gcagccccca gatctcgtat ttggttgtca gcaccggcgc
     2461 ctgatctaca ttgactttcc ccacctgaat atctctatcg agccggtctg caaactgact
     2521 gaacatttct tcgctggcct gacagggcgg acaccagggt gcagagaaac gtaccaccga
     2581 tattcctttg tactgctcta tctggcggaa attatcttcg ttataagctg ttaatgtacg
     2641 catggtgatg acctcgcaaa atgagtgaca attcagaaat ggctgcgtta tgacaaaaaa
     2701 atacgacaca gccattgacc tacctactag atggttggta tattgccacc catcagatgt
     2761 ttatgcaact ccagtgcgcg acgtccagtc gatgatactg ccgggctgtg caaatccctg
     2821 ccgggatact cctttttgtt ttttgtgagg tatacgatga gtaagctttt caccccctac
     2881 aatctgtctg gcctggcgtt aaaaaaccgt gtagtcatgg caccgatgac ccgcacccgc
     2941 accatgaatg aggtgccgga tgaggtcgtg gctttgtact atgcacagcg tgcttctgct
     3001 ggcctgctca tcaccgaagg gatgccggtt tcagaagaag gccggggtta cctttatacc
     3061 cctggtatct acaacgacga acacgtccag ggctggcgta aggtgacaca agcggttcac
     3121 gccaaaggtg gccgtatttt cgcgcagctc tggcacgtcg gccgtatgtc tcacgtctct
     3181 cttcagccag gccacatagc gccggtttca gcgggcaccg ttcaggcggt caataccacc
     3241 gtttttgcgc tgaccgaatc cggagaaccg ggcccggttg taccaagcca gccacgcgcg
     3301 ctggaaacgc atgaagttaa acgcatcact gcagacttcg tgcactccgc acgcctggcg
     3361 atggaagccg gctttgacgg cgtggaaatc atggcggcaa acggattcat ctttgaccag
     3421 ttcctcagta gcgaactgaa cacccgcacc gacgaatacg gcggctcggt ggaaaatcgt
     3481 cagcgtttcc tgctggagac cattgacgcc gtggcggaag ccgtgggtaa cagccacgtt
     3541 gccgtgcgcc tgtcaccgtt cggccgcatt tatgacctcg cgccgtatga aggtgaagag
     3601 caaacctggt cagccatcac cgacgcgctc ggtcagcggg aactggccta cgtacacctt
     3661 tactatcagc cggtgtacac caaagcgcca cttccggaag gcttccgccg ccgttttcgc
     3721 aacacgttta aaggcaccat catcgctgcc ggcggtttta cccgtgatat cgcagagcag
     3781 gctctggaag atgatgagct ggatctggtg gcatttggtg tgccctacat cgctaacccg
     3841 gatctggttg aaagaatgca aaacggctgg ccactggcag aaagtgaccg cgccacctac
     3901 tacggcgtca gtggttcccc ggaaaaaggc tataccgatt acccggtctg gcaggcgcaa
     3961 taaatcccat acggtcgcgg ttctctgatc agtgagatcc gaccgcccaa cgtctttgag
     4021 gaatcattat gcaaacgctg aaacacaccc ttaccatcga tatctggtca gatttggtct
     4081 gcccgtggtg ctggattgct aaaaaaagat ttgaacaggg tctgaatcgc tttgaatttc
     4141 gcgaccaggt ggtgatccgc catcacagct accgtctggc cggtggtact cccgcgatgc
     4201 cttttaagga tgccatcgtt aaaaagctgg gcagtcagca ttcagcggag ctgatgatgg
     4261 atcaggtggg caccgccggt aaatctgaag gtctgatcta caacttcgac ggcatgatgt
     4321 ttggtgatac agaagatgca cacaccctgc tggttgccgc gcgtaaggcc ggaattgcgg
     4381 acgcagtgga agaacgtttt tatcacggca gtatcaccga aggtcgctct ctctttgacc
     4441 gtcagcagct cgttgcaatg gccgtagaag ccggtatgga gaaagctgac gccgaagccg
     4501 ctctggaaaa tgacgatttt cgcgccaccg tttccgacga tgaagcccac gcacagtcta
     4561 ttggcctcag cggcgttccg gtttttgtga tgaacgagaa atacgccatc agcggggctc
     4621 agggggcaga caactttttg aatgccctgc gtcaggtctg ggatgaacag caaaccgaat
     4681 tttcagccac tgcgggtcag acctgcggaa cggatggctg cagcatttaa tccgtcaacc
     4741 gccggcagtt tcacgctgcc ggcaacgtct tacccaccag taatggagtc tgaaaatgaa
     4801 tacatttttc aaaggtaaaa aactgcttgt cgtcggcggc accagcggca tgggtctcgc
     4861 cgtggcacgc atggtactgg aagcgggcgg cagtgtggtg ctgaccggga ataaaaaaga
     4921 caaagccgaa gcggtacaaa aagagctggg cccgctggga ccggtggcgg tcatcgcggc
     4981 caacctgatg actgaagaag gtatggaaac tatccgtcat gaaatcaatg ccagccatcg
     5041 cgatatcagc ctgatggtaa atgccgccgg gatctttatg ccgaaagggt ttaccgagca
     5101 cagctttgcc gattatgaca tgtacttttc gctgaaccgc gccacgttct ttattacgca
     5161 ggatgtcgtg aagaacatgc tcgccgcgaa gctcgaaggg tctatcgtca acgtcggttc
     5221 gattggtgcc caggcagcac tgggggactc gccgtcctcg gcctattcaa tggcaaaagc
     5281 gggtctgcat gccctgacgc gtaatctggc gattgaactg gccagcgcgg gtattcgtgt
     5341 caacgctgtg tctcccggga ttgttcatac accaatatac gaaggcttca tggacaaagc
     5401 ggatatcgct gatgctatga agtcgttgaa cgatttccac ccgttaggcc gcgtcggaac
     5461 cgcagaggat gtggcaaaca ccattctctt cctgttgtct gacaaaacat catgggtgac
     5521 gggcgctatc tgggatgtcg atgccggcat tatggcggtc agacgataac cccggtacgt
     5581 tgacaagagc cgccccttta cgggcgtcat ttttttgtcg ccagaaatgt catcagcagg
     5641 cttcactcag gatattcaca acctgttcat ccgtgccttt tttgttcccg gcacagggtg
     5701 ttatgccggg ttctgacgac atcctgacag gacaaacggc cagagagaaa ggggttatac
     5761 cctgttaggg gccggtgtcc gcagtacctg tgaaattctt ttcatccctg ctgtcagcat
     5821 agtccgtggg cacgccagat ttaaccggat atgtccttcc ccattgtcga caaacagcaa
     5881 gcccccttca agaagcaccc ctgactcccg ggcaaaatac agcgataaat cctcacccac
     5941 agtgtcgggc aggtagtggc taatatctat ccaggccaga tatgtccctt cggggatcga
     6001 gaacctggtt tcgggtaaat agcttttgag gtagtcgtgc aggtactgga aattgccgtc
     6061 aatatattcc ctcagatgga caagccagtc atcgcattca ctccacgccg ctttgtttgc
     6121 tgccaggctc agcggagaga tgaactcgtc gtgtctgaga cgccactcgc ttctgacacc
     6181 gggatccgga ataatgatat ttgccaacaa attcccggcc agattgaatg ttttactcga
     6241 ggacatgcag gtaataatgc gtgtagaatc agggaaaaga gaggcggccg gtgtatgacc
     6301 gataccactt cgggacaggt cacagtgaat ttcgtcagat atcacccaga tatcattggc
     6361 caggcaaatt tcaataatcc gcttaagttc atcaggccgc cagactcgtc cggtcgggtt
     6421 atgcggatta cacaggaaaa gaattttcac acgtaagtcg gcctgactgg ctttgcgtgt
     6481 aaagtcttcc cagtcaggtt cccagccacc tgctgatttt tttaacgccg agtacaccac
     6541 gcgacgctga ctgtattcac ccgccttttt aaacgggcca tatgaaggcg tcataataag
     6601 aatactgtca tccttgtcgg tcagaagcgg gacgagacgg ttcagcgcgg gaataatgcc
     6661 cggagacagt acaatgtctt ccgttttgaa acggtgacca tattgtcgct cacaccagtt
     6721 gccaaagatt tcatagtatt cttcgtcgta gattttagtg tagccgagta tttttctatc
     6781 cagacggtct ctgatggcct gaagaatcgg ctctggtgtg gcaaaagcca tgtcagcaac
     6841 ccagaggttg attagccctt ctgccggata ccgcattgca aattcggact gccccgcaaa
     6901 caggtattcc cgccagccgt ccacggtaag actgtctgtt ttctctctgc ttacgtactc
     6961 atcaaaatca tatttcattt catgaacctg ccttaggtgt agtctgaaac gtcgacctca
     7021 gtattcctgt cagtctgatg ccggagcggg aaaactggct cgtgtgatta acataagaga
     7081 atcattacaa ctgcatgaat taattgcgtt attgaggttt tctcgccttt gccatcggct
     7141 gacgggggga tttctcgcgt gtcaccatca caatgccagt cagcactgcc agggcagaaa
     7201 atatcgttct gaccgtcagt gattcaccca ggaataccac accccctagc attgccaggc
     7261 agggaacgct gagctgaagg atactggcgg taatagagcc gagggagggt aaaagggtat
     7321 accacaatac ataggcaccg gctgaggcga cggcaccgga cagcaatgac aaagcaatgc
     7381 ctgcagcatc agagtgaccc tgcttcataa acagcaacgt aagagcgaga gccatcggcg
     7441 ctgcgagaat aaaattagcc gccgttgaag ccccggcagc ctggcccgcc ctccccctga
     7501 cggaataggc ggcccaggct aatccggaaa cgatcatcat aagtgcactg taaagcggcg
     7561 gtgccttcgt cccgggtaac agcagggcag caattcccgt cagagccaga actaaaccgc
     7621 aagcccgcat agcggagagt gattctcctt taaataatcc gtggatcacc atcgcaaact
     7681 gtacggcacc aaaaagtaac agcgcaccag ccccggtatc gagatggata taggcgacag
     7741 aaaacagcac cgcatacgcc atgaggtaaa acccgctcag cggacgccac agcgataatg
     7801 tggtcctggc gtgataaaag aggaaggggg acaggacgaa tgcaccactg gccagcctga
     7861 ggctgctgaa tgaaagggga tcaatgtggc ctccctgcag ggccagacga cacagaatgg
     7921 agtttgccgc aaatgccagc attgccagtg atattttaag aatgagcgcg cacctggcca
     7981 ttcgagaagt cctcacaaaa gccttgtaaa ctaccatcta gttggtagca tagcgtaagt
     8041 gatcgccgag caggaagcaa taaccagctt ccaaactgga aggtgaggac aggcattcgg
     8101 aatgaattct gtttcacatc cccagtggag gacggaaaac gcgttatgcc agatgcagag
     8161 cagaagatta tttttctcct gcgatcaaac atatgacatc agtttaaggc ccggaatatc
     8221 ctatgaaaaa actaaaattt acgttcaaaa atgcggcggg tgaagaactg gccggattgc
     8281 ttgaacttcc tgaaaatcct aaagcgtttg cgctgttagc tcattgtttt acgtgtggca
     8341 aagacctcaa aggcgcggcg cgtattgcgc ggaaactgac agagaaagct atcgccgttc
     8401 tccggtttga ttttactggt ctgggaaaca gcgaagggga tttttccaac accaacttct
     8461 catccaatat ttcggacctg ctttgcgcgg tagattatct ccgccgacag tacgaagcgc
     8521 cttctttgct catcggtcat agcctggggg gatcggccat cctgtctatc gccggcgaag
     8581 ttcctgaggc aaaggccatt gtcaccatag gatcacccgg agaactgaca cacgtaaaac
     8641 gtctttttaa ggatgatgtt gaaaacatta accagcatgg agcctatccc gttgagctgg
     8701 ccgggcgggt atttacgtta aagaaacaga tgctggacaa tattcaggaa cacaaaatcg
     8761 ctcataaggt gttcgccatg aacaaacctc tgctgatttt tcatgcgact gaagatgata
     8821 ccgtgttaat tgagcaggcc gagaaaatat tcaaagcagc taagcatccc aagagtttca
     8881 tttccctggg taaggctgat caccttctga cacatgctca ggatgctgaa tacgttgccg
     8941 atatcattat atcgtggagc gaatgttacc tataaacaga gtaaatgcgt tcaaactcgt
     9001 agcgctgagg gcgattttct gcagagatcg gacgctgttt atgctggact gattttgcga
     9061 taaaggctta ggccgatgca tacaggcggg gctgaataag ggtgaggccc ttgggcgagc
     9121 atccttcatg caccggctga atgaaatcag ggatctgggg gtgggaggat cagcgttacc
     9181 acgccaccgg cgctgacact acatacggcg gcgataacac tctggaatac ggtttatata
     9241 gaaagaacca ttgagccgct taagcaaaaa ggagtccctg ttaatgaact gctggtctct
     9301 catccttctc cactgctgta caaaatatag tcttagcgtg ggataattaa tgagatggtc
     9361 actccctcct tcccggtact atgctgagga caggctttca ttcggagaac tatcatggaa
     9421 aacattgcgc tcattggtat cgatctgggt aaaaactctt tccatattca ttgccaggat
     9481 cgtcgcggga aggctgttta ccgtaaaaaa tttacccggc caaagttgat cgaatttttg
     9541 gcgacatgcc ccgctacaac catcgcaatg gaagcctgtg gcggttctca ctttatggca
     9601 cgcaagttgg aagagttggg gcattcccca aagctgatat caccacaatt tgtccgcccg
     9661 ttcgttaaaa gcaataaaaa cgactttgtc gacgccgaag ctatttgtga agctgcatcg
     9721 cgtccgtcta tgcgttttgt gcagcccaga acggaatctc agcaggcaat gcgggctctg
     9781 catcgtgtcc gtgaatccct ggttcaggat aaggtaaaaa caaccaatca aatgcatgct
     9841 tttctgctgg aatttggcat tagcgttccc cgaggagctg ccgttattag ccgactgagt
     9901 accattcttg aggacagtag tttgcctctt tacctcagcc agttattgct gaaattacaa
     9961 cagcattatc actatcttgt tgagcagatt aaagatttgg aatcccagtt gaaacgaaag
    10021 ttggacgaag atgaggttgg acagcgcttg ctgagcattc cctgcgtcgg aacactgaca
    10081 gcgagtacta tttcaactga gattggcgac gggaagcagt acgccagcag ccgtgacttt
    10141 gcggcggcaa cagggcttgt acctcggcag tacagcacgg gaggtaggac gacattgctg
    10201 ggaattagta agcgaggtaa taaaaagatc cgaactttgt tggttcaatg tgccagggta
    10261 ttcatacaaa aactggaaca ccagtctggc aaattggccg attgggtcag ggatttactg
    10321 tgccggaaaa gcaactttgt cgtcacttgt gctctggcaa acaagctggc cagaatagcc
    10381 tgggccctaa cggcacgaca gcaaacttat gtagcataac ggcagaaata caccggttta
    10441 aagaattact gatctggttt tgcgaatact gatattgatg atactaacgg cccaccggcc
    10501 tgttgaggaa cctgtaaaac ggaaaggctc attgaagccg tatattttct ggaggttcat
    10561 caggcgcgga actcatcaag gcgcgggaat aaaatcccat tcagacgccg gatagattca
    10621 agcaagccaa cttgtcgtca aaatcggtgt tgcaaaaacg ggagtgacca tagattccgt
    10681 tttccaagcg gacccctaca aggggctgct gaaaaacgat aaccaactgg cgatgttatt
    10741 caccctggcc aacctgtttc gggtggacca aatgatacgt cagtgggaga gatctcagta
    10801 aaaaccggaa ataacaccag aaatggtgga aaaaatagcc taaataggct gattcgatgt
    10861 gtttgcggga caaaaatcgg cccagatccg cgaaatttta atcaacgagt cagcttggga
    10921 agacatgacc tgcttattcg caccttccct aaaggcgtct ttggcttcgg tcagcgaaca
    10981 ctgctgtttt tctttgcagg acggtgaatc tttgtagtcc gtcatctgcg ccagcagctg
    11041 atagctgtcg tcaagctgca tctggctgcg ctctttttcc atcgcctgca ccgctttctg
    11101 gctaaacgcc gcagagtcat cggtgatcac cggattaaac gttgggtcca tcgtgcccat
    11161 tttttcctga tgatgtaccg gaatgtcgca cccagggaaa gcgccggtga taaagaattg
    11221 tgccgtcgca acggtgcgtt gcagactgtt ggcataggta tataccgtgt ccggcgtcgg
    11281 gcattcgcct gacgtgacca tccccagctc cgccagccat tctcgcatgt agtggcccat
    11341 ataaatttcc agcacaccgc ctttcgtggt gagctgcccg ccgggcacat cccactccgg
    11401 ccactgattc ggcgtggact gctccagcac gctgccatta ttggccaacg gcgcgcgcaa
    11461 gttgtgtcgg ctcatcatca acacttgttg cagttgataa ccttccggcg ttgtctgcgc
    11521 ttgcgcggcg gacgacaata aaacagcccc tgccacagcg gcggcgagta tcaatttttt
    11581 catccctaca acctcttgtt gttatcaatc ctcatagagt gtgacagaaa tatgacattt
    11641 ttccgggaac ggtttcgcaa aacgggagat tccagaagat aaccggcagg tcagcgtgtt
    11701 ccggttactc cgagataaaa acctcatact taatattgcg ggcgcaataa aaagtgccgt
    11761 ccgtcagata cagttcacga aatcgcgtgt tatcagagat gttgtccagc agggaacgtt
    11821 ccgtatcgac aaattctttt tgcacgcggt aatgaacggc gttctccgtt tcaaaagaga
    11881 catattccgt ggtggcgtag ggcttatttt ttgatttcac gtacacgata tattgcacgg
    11941 tactggccgt cagccccgtt ttcgccgcga tctctttgag actcaacgtc tcagaggcat
    12001 aaagcgcctg aacctgcgct atgcgtcggt gattatacgc cgtcacccga aggctcagtt
    12061 tcagccgata ggccatattc cgcacggcgg taatattagt gtgaagcagt tgcgctatct
    12121 gctctgtcgt gaggatgccc gcgttttccc gcagaatcgc aaggctttcg tcgttccaga
    12181 taaatgccat tgggtatctc tccgtacgcg tcgttcatcg cgccgccagg cgcgcaaacg
    12241 tggcctctaa ctcagacggc ttacgcatac cctggtgtag ctccagaacg cgtccttcgg
    12301 agtcaatcag tacggaggtc ggcgtgccga tcacctgata acgttcctgg gtaatgttga
    12361 gctgatcgcg caccaccgga taggttatct gatgttttgc cagcagatcg ttgatcctga
    12421 ccgtttcagg gtcggtattg accgccacaa ccaccacttt atcgccccat tttttgctca
    12481 gcgcttccag cgtgtccatt tccgctaggc accccccgca tcccgcagac caaaaattca
    12541 ggtacaccgc ctttccttgc cagcgttcaa ggcctgactc ctggccttgc agatcaaacg
    12601 ccgccagcgc cggggccggt gccccgaccg ccagcttttc ttctttacac ccgcttatca
    12661 ggatcgccgc cgcgagtaac agcacattat gccagcgcat gttgattggc ctcctcaccc
    12721 agatatttac cgtgttgcag ccgcagaata cggtcggcaa actgcccaag cgcagggttg
    12781 tgcgtcacca tcacaatcgt gcgcccctga cgatgcagat cggtgagcag atccagcacc
    12841 cgctgctcat tctcttcatc caggttgccc gtcggttcat ccgcgaaaat aaccggcggt
    12901 tcgttgacca gcgcccgggc gatacacaca cgctgctgct caccaccgga aagctggctc
    12961 ggcaggtgcg tcacacgatg cccaagccct acctgttcca gcaccttcct cgccgccgct
    13021 tcatccacca cgctgtggta atgctgggcg agcatgatgt tttccagcgc agttaagaac
    13081 gggatcaaat ggaactgctg aaataccagg ccgattttct cggcgcgaaa gcgacggcgc
    13141 ccctcttcat ccagcgcggc ggcatcggtg ccatcaagaa acacctgccc ttccgtcgcc
    13201 gtatcaaggc acgtcagaat attcatcagc gtggttttac cagaaccaga agcgcccata
    13261 atggcgacaa attcaccctg cgcaatgcgc agattaatgt catccagggc ggtaacgtca
    13321 ccgaaccgtt tgtataagtg gcgggtttcg atcgccacct gagggatatg cgtaacggac
    13381 atggcgctac tctcctttca gcactttagc aggctcgacg cttaccgcgc gtcgcaccgg
    13441 aacaatcgcc gccagaatgg cgaccagtaa agacaacacc agagtaatgg gcaacaccgg
    13501 cagacgcagt gaaatggcgg cattaaacac cgttaatccc aacagttgcg ccagcaaata
    13561 tcccagcacc cagccgcacg ccaccgccgc cagcgcgatg atgctggttt ccagcagaat
    13621 ttgccgcacg atatcgccgt tgctggaacc aagcgctttt tgcagcgcaa actcgcgcgc
    13681 ccgctcgccg acaatcgcca tcagcgtggt attcacgcac agcgaagaga gcgccagaat
    13741 cacgatcgag accagtccca tcagaccttt aattttatcc agcacctgcc cttcggaagc
    13801 agagacctta cgcaccggac gaatctccag gtcaggatac tgcgcctgca accggctggc
    13861 atagttctcc acctggccga catcgttact gacgctcagc aagccgtggc tgattttgcc
    13921 cggctgatgc agccaggcct gcgccacgtc gaggctgacg atcagcatgt tgtccgtcgc
    13981 atcgccagac tccacaatgc ctttaatctg caaattctta cgctgattgt gatccaccag
    14041 cgtgatgctg tcgcccggct gcacgttgag gcgttccgcc agtttgacgc cgatcatcgc
    14101 attacggtcg tcaaaactaa cgccaatcca gctaccggtg acctgccagt acggcaccag
    14161 tttttgcagc gactcgaacc acacgccaac catcaccact ttttccagct cggtacgcgc
    14221 catgccgtac aaccacggac tggcgccatg caccagcccc tgcggcgcct gatcgagaat
    14281 gctctgcaac tcctgctgcg gcatactgga accgtgcccc ggcccgatgt aaaaattcgc
    14341 gccgaaggtg cgcagttctt cgctcatttt ggtgttaatg tcgaaccaga cggcagaaag
    14401 cgccgtcacg atggtcgccc ccaccatcag cgcggcaaac accacgctga cccgctgaaa
    14461 acgcagacgc agcgcccgcc acaccagcag ccagagcatg gtacgtttag cggccataca
    14521 gcacctccac aggatacagc cgggcaatcc gccgggccgg gaaccaggtg ccgatcaacg
    14581 caatcagtac cgcaatcacc agtacgcacg gcaccacaat ccaggcaaaa ttaagcggcg
    14641 cgtcgaagag catgacgcca atcgctttcg ccagccccca cccggcaata catcccagcg
    14701 caccgccagc cagcccgctg gacgccgctt ccaggtagaa cagcagcata atttgccact
    14761 gtcgcgcacc cagcgctttc atcaaaccga tctctttggc gcgttccata atggtgctgg
    14821 tcatcagcga ggcgatcccc attgcggaag ccaccagcgc cgcgacggta acgaccgcca
    14881 tcagcaactg aattttatcg atcaccaccc cttcggacgc cgcgacctgc cataccgggc
    14941 gcacttccgc accggaaatc gcctcttcca gctgatgcgc gatcgacgac acataggccg
    15001 tgcaatacca gaggtcgtac tcttcggcat tgagcgcgtc caggttttcc cgcgcgcggc
    15061 gggacagttc gttttccggc accgtcagcg ccgagacgcg aatcgcctgc acttttccgg
    15121 ggagccccag caggtgctgt accgtgctta gcggcatcac cagttggtta tcttcatcgc
    15181 cgccgctgga gaggataccg ctgacggtga cctgcactgc ttcgccttcg gtacgtaatg
    15241 tcagcttatc accgggtttc cagcccattt gccgcgccag cgcgtgcccg actaaggtct
    15301 gcggctctgc gcctgcgggt tcctgcggcc agtcgccggt cacctgccag tatgggctga
    15361 ccgttttctg ccccgtctca tatccctctt catcaggaat atccactggc tgactgaaga
    15421 aagtgcccag aatccgcact ggttctccct ccacgctggc ttcgccgccg agcatcggcg
    15481 caaacccgac aatgttgttt cgccagaaga tatctttgat gttcggcagc tcggcttcat
    15541 caagaaaatc ctgaccggaa agcggattac tgctctcact aaacagcgcg ggcagcgcag
    15601 cctgtccggc gggttcaatc aaaatgttcg caccataaga cttcagctct ctggacattt
    15661 tgtcgccgat atcaatggac accgccagca gcgccgagat caggctggag gccagaaaaa
    15721 cggtgattat cgccagcact ttgcggcgta aattgcgccc ccaggattgt cgtaacatcc
    15781 gccacagcat gattattcct ccctcatgtc ggcaggaaca aactgctccg gcgtttcacg
    15841 gaagcgttca tagttagcct ctgacgagaa gaaccaggtc ttgccgccat agctgtattt
    15901 gtaatcggct gaggtattgg tcaacgttga accatcgacc ggatcggtca ctttaatagt
    15961 catgaccgtc gagaagtagt tcacccctgt cgccagttct ttaccgggga tcaccagctc
    16021 tttttcatca ttgtgccagt tttcaatcgg caccgggtta cagccaccgg ccttgccgat
    16081 agacggaata aaaatatgca ctccgcaggc gacgcagata acctgattgc cctccatgac
    16141 ataaccctga tcgccgcaca gcaggcaggc gtcgaacacc acgccaaaac gcagcttgtc
    16201 gggatagcgg ttaatcacga agaagcgcac cgctttgcca tcgtccgcca cccagacgaa
    16261 acgatgcagt ttaccgtcac gaagctgttc aaccggcagg cgcaccatgc catcgctccc
    16321 cagcgttacg ggcacggctt cagagagttg cggcggctgc gaggccactt tatcccacca
    16381 cagttggcct gcgataacga ccaccgcgca gccgattgtg accaaccaca gccgcaaagc
    16441 gttgcgacgc tgcgccagcg ccagacggtg agcaatcggt tcttcggttt cccgcgtctg
    16501 tcgaaaagcc cgcaacagcg ccggaagcca gcacagcgcc agggccagca gcagcgcggc
    16561 tcccgcccag ttatacagcg ccgtgttatt tgtgactttc gccacgaagc tcagcagtga
    16621 ttttcccagc ggaacaacct gtaatttcat cagcaacaac agcaggttgc cgctcagcgg
    16681 cagccagatc atcaccagca gaatcagcgt taacggccag tacaggccgc gaatacgccg
    16741 cagcagcatc gcgcagagta cgcccgccag acagaggatc gcaaaagcga gaacgacggc
    16801 cgtcaggttt aacagcaggt cagtattcag cacatgcgta ctggtcagcc cgcccagatt
    16861 agggtccagc gcccaatggc gggcagcgcc gaaaatcaga atcccctgcc acagatagcg
    16921 gatacgcgtt gaagcccacc agaaactgag gacaaacagc agcgatacca tgacctccgc
    16981 cccaaccagc agcagttgta ccggttggct gccgtgaata aacagtcccg ccagcacgcc
    17041 ggcaatcagc ccggtcagca gcgtccaggt cagcggacgt aaagagggag gatcgtttcg
    17101 actccagaga acaccggaaa gaagcgcaat gcagaaaaag acctgtagcg tcgtgacgaa
    17161 aaagtaactc ataacttcga ctctgtacgg cgggttgaat taagcgacgg gcatatgatc
    17221 ggtctgacca acgcgccaga agggggaatc ctcctggcgc gttggttagt cggttttagt
    17281 tcagaccgac atatttaaac tcgtagctca catcaaacgg tttccaccag cggcctacgc
    17341 ctgtttcgct gtcagtatgg cgatgcatcc cggcttttga cggcggttca atgtggtagg
    17401 tcactttata gttgcccacg cccatcattt tgatgttcgc gccatagtgc gggccatcgc
    17461 tggcaaccat cggcatgaag gtgccttcct gtttttcgcc cgtgtcgttg ttgaccaggg
    17521 tgtagctgat ggtcaggtac gggatccatt cccctgcgcc aaagccgttt ttattgcctt
    17581 ctacagcgtg gatatccgct tcaaggtgaa catcggcttt tgctgccggt aagcccatgc
    17641 cgcgcggttc catatcaatc ggttgcaggt aaacggccgc cagctccatt tcattcatgg
    17701 tgacaggctc gcctgccggg tactctttaa aagcaaacgc ggctggcgca atgaaaatgc
    17761 tggccatcac tgcgctggca atcagggttt tcttcatggt catcaaacgt atcctctcgt
    17821 ctaaaacaac ggctatacaa cgattatggg ttatttttta tcgtctcccc gggaaccgcg
    17881 cttttgcgcc gcatcaccca cagcgccacc agcgccgcga gcagcaatac gacctgcggt
    17941 aacaacgttt ccacgtaggg ataaatcccc agccagctga tttcagggaa gccgttaatc
    18001 aacgtaggct ggaacagttt gccttccacc agttccagaa cgcctttgcc cgcaaagacg
    18061 aaggccatca gatacatgaa actgccggta aacataaaga agggtttcag cggcaggcgc
    18121 accactgagt aacgcatcac cagccaggcg agcagcagca ccacgcagcc aatcacaaaa
    18181 ccggcgccaa tcgccatatg gccggatacc gtgtttgcat cgccaatcag agcgtaatag
    18241 aacagcaccg tttccgcccc ttcgcggtac accgccagga agctggtcag ccatagtccg
    18301 accagggagc ctcgcgacag ggaatgagac agtttgcctt ccagccaggc tttccagtgg
    18361 cgcgcttcca ctttggacag cagccagtaa ctcataaaga acagcatcac gacggcaatc
    18421 agcatcgtta tgccttccag cagttcacgg ctggcgccgg agttagtaaa cagcatctgg
    18481 aagatagcgg cggtgatgac gctggcgatc agcgccacaa ttaccgactg acgaataagc
    18541 ggcagcttat cctgatggtt gtttttcacc atgtaggcca cgattgccgc aacaatcagc
    18601 agcgcttcca gcccctcgcg cacgatgatc atcagactat agagcagcag actccactgg
    18661 gtttcttcgc cttcgcccag catcgtcacg gctttttgca gatcctgcgt cagcgcgctg
    18721 gcctctgcat tcaggcgctc aaccggctga ccggccttca tcagactgac caggcgggta
    18781 aaatacgcct ccagcgtggt tttaaatgcc gaatcgcgag agccgatttt gttttccatg
    18841 ccgctggctt cgaagcggtc gaagtaggta tcctggatat ccagaatcgc attcttcgca
    18901 tcgccgccct gatagcgcgc tatcgcgtcc tgaatgctct ggttaattcc cgtcgtcacc
    18961 tcagcccagt cggtgcggtt atttccctcg tccgccgccg gaatgttgtc tgcgctttgc
    19021 gctgcggcaa cctgctgatc gtcacgggtg gttggcaagc cgggtaagat atcctcgata
    19081 tcctgtagca gcgtagtgac ctgataggag acatcgttga gatggtcagg ttgcgcggtc
    19141 agcgcaatca gggatgagaa ttgttggtta atggaggcgg catcttttgc agaacggttt
    19201 tgtctgaggg acatctccat ctcagagttt ttaaagccct gatagtgcgc ctgttgaacg
    19261 tgctgactgg caacgctgta attcccggcc tgatattcag tgaccgcctg cgccagcaga
    19321 tcgtcgatcg tcctgaaact ctcctgccag tgaacggcaa tgtcgtccct ggacagcgcg
    19381 ttgtgctgct cttcggccac cagacgatgt ccgccatcca gcaccggttc cacttcgcgc
    19441 agtgcggctt tcagccagtc aatgcgcgcc tggacgtcag cgagcggttt tttctcgcca
    19501 atcattcgac ggatctcgcc gaatgcgctc tccatctcgt aacttttgcg cgcggaaatg
    19561 ttgatgcgga tcggcccttc caggttctcg aacacctcaa aataggccat ttgtaccgtg
    19621 cggcgcgcct cgtcggcatg ctgttgctga taaagttccg ctgttttatc aagacgttgc
    19681 tcgatatctt caatcaaagg cgcataattc gtcgacgccc agacactcat gcttataaac
    19741 aagccaaaga gagtaaccaa caaagagtta cggaagttac gcacgtgcac accgccaaag
    19801 aatacaaatg ataattatta tcatatcttt ttgtcgcgtt atacatgacc tggatcataa
    19861 aaatgtcagc agacgacaag ttatgtaaac ttatttcatc aaatcgtgat gaacacacac
    19921 attatgcgtt gataaaaggg acgttatctc cctgtttttc tcatggaatt aacggcaagg
    19981 caggcgcggt aacagaggaa taaatccccc tgccgacagt gatattattc attatcggca
    20041 ggcagaaata aaacgcgtta ttgcgtacag caatattcaa agattaaggt tatttcgatc
    20101 gctggcaaga cgctgtaaga attgaccata tccctgcggc cccatccagt agttaatact
    20161 tttctcaacg ccggttgatg tcaacgtcgc accggaaata ccgtcaacgg tatattcatc
    20221 ggcatgttca ggtttatcct gtactatttt caatgcagga tgtccgctgt tatctaataa
    20281 tcgtttccct ggccactgtt tgcgccagtt ggcgtcttcc accctagccc ccagaaacgg
    20341 cgtttcccgt tgctgataat aatacagatt tctcaccgta cgaccgtcca gccccagagc
    20401 aagaaacgca tgcatcatgg atttcgcacc cttaccggta actggaatga taacctgctg
    20461 aatttcatta tttttatctt tcacaaagaa cacatccgcc accgtacagc gctgacgaac
    20521 ctgcgctggg tcgcgttcag gggcaagttt ttcacacttc tgccgcgcgg tgtccgcgct
    20581 gctgccagcc accagttcgc cggaatctaa attaacatgg cgttgaataa tataacgatg
    20641 atagagcgtt tcgactgatt ttttatcctg ggtctctgat ttcatcaggc ccgcagcgtg
    20701 taaaattgcc gcctgttttt cctcctctgt cggctccgtc atttctccct ggaacagcat
    20761 aaaccatgcc gccgccgcaa caaaaataag gacacaaagc accatcattg atgcaacaat
    20821 aattttaccc ttgcgcattg aattgttatc cctgtcaaaa tggaaatcga aaaaatcgcc
    20881 tgaacgtatc acagactttc attcaattaa aacagatatg ccattatcaa ttcaggtttg
    20941 caacgtcagg cagcggtaaa aaataataac tggcgtcggt aaaaaagcag caaaaataac
    21001 agaaaacacg ctctccgctc gttttacaca tccttacaat gggttaaaaa atgccgggtt
    21061 tccccggcac gctatcaaaa catggctgcc cgccacagac gtaacttcat gccccagtag
    21121 ctggtccagc cgctggtcgt agttaccacc tgccccttcg acaccaccac cagcgttggc
    21181 gtgacgctga tttcccagtt tcgtgatatc tcaccgccgc tatcattcac gacggggaac
    21241 gtcacccttt tacgcgataa ccagcgggaa acctccccgt cattaccgga acgcagcgcg
    21301 atggtcatga cgctctcccc ttccgactgc aaacgggcga catccggcgt ggtgaaacgg
    21361 cagataccgc accagctcgc ccagaagtag agcagcaccg ggcgttcttc actgatcgac
    21421 gccagcgtta cggtttcccc gtccagcgta tgcagcggcg tgctgtcaaa catggccggc
    21481 atctgcggag aacgccagac atccagcagg attatcacgc cagccagcac aaccagtaag
    21541 atcgcgcctt cacgcagcca gcggcgcagt ttactgagca tgggccaccg ccagtttttc
    21601 tttcaccacc gcctcaaggg tctcccacga taccgcgccg gggatcatct cgtcgccaat
    21661 gatggttgcc ggcgtcccct gaacgccaac cagccgggcg agttgcagat tggtgctcaa
    21721 cgtctccatg cttttctcat cggggtcagt ttggatatag agaattattg tactataagg
    21781 gcttccccgg catgtcaatg ccggtgttta cggtttctgt ctgc
//
LOCUS       DAPOAV010000077        21446 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.077, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000077 DAPOAV010000000
VERSION     DAPOAV010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21446
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.077"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            131..784
                     /gene="nfsB"
                     /locus_tag="RN951_003287"
     CDS             131..784
                     /gene="nfsB"
                     /locus_tag="RN951_003287"
                     /EC_number="1.5.1.34"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-insensitive NAD(P)H nitroreductase"
                     /protein_id="HDX2528244.1"
                     /translation="MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQ
                     PWHFIVASTEEGKARVAKSAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQE
                     DADGRFATPEAKAANDKGRKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLD
                     AVPIEGFDAAILDAEFGLKEKGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV"
     gene            892..2139
                     /gene="ybdG"
                     /locus_tag="RN951_003288"
     CDS             892..2139
                     /gene="ybdG"
                     /locus_tag="RN951_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel YbdG"
                     /protein_id="HDX2528245.1"
                     /translation="MQDLISQVEDLAGIEIDHTTSMVMIFGIIFLTAVVVHIILHWVV
                     LRTFEKRAIASSRLWLQIITQNKLFHRLAFTLQGIIVNIQAVFWLQKGTEAADILTTC
                     AQLWIMMYALLSVFSLLDVILNLAQKFPAASQLPLKGIFQGIKLIGAILVGILMISLL
                     IGQSPAILISGLGAMAAVLMLVFKDPILGLVAGIQLSANDMLKLGDWLEMPKYGADGA
                     VIDIGLTTVKVRNWDNTITTIPTWSLVSDSFKNWSGMSASGGRRIKRSISIDVTSIRF
                     LDEDEMQRLNKAHLLKPYLTSRHQEINEWNRQQGSTESVLNLRRMTNIGTFRAYLNEY
                     LRNHPRIRKDMTLMVRQLAPGDNGLPLEIYAFTNTVVWLEYESIQADIFDHIFAIVEE
                     FGLRLHQSPTGNDIRSLAGAFKQ"
     gene            complement(2220..3596)
                     /gene="pheP"
                     /locus_tag="RN951_003289"
     CDS             complement(2220..3596)
                     /gene="pheP"
                     /locus_tag="RN951_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine transporter"
                     /protein_id="HDX2528246.1"
                     /translation="MKNASTVSEDTASNQEPTLHRGLHNRHIQLIALGGAIGTGLFLG
                     IGPAIQMAGPAVLLGYGVAGIIAFLIMRQLGEMVVEEPVSGSFAHFAYKYWGPFAGFL
                     SGWNYWVMFVLVGMAELTAAGIYMQYWFPDVPTWIWAAAFFIIINAVNLVNVRLYGET
                     EFWFALIKVLAIIGMIGFGLWLLFSGHGGEKASIDNLWRYGGFFATGWNGLILSLAVI
                     MFSFGGLELIGITAAEARDPEKSIPKAVNQVVYRILLFYIGSLVVLLALYPWVEVKSN
                     SSPFVMIFHNLDSNVVASALNFVILVASLSVYNSGVYSNSRMLFGLSVQGNAPKFLTR
                     VSRRGVPINSLMLSGAITSLVVLINYLLPQKAFGLLMALVVATLLLNWIMICLAHLRF
                     RAAMRRQGRETQFKALLYPFGNYLCIAFLGMILLLMCTMDDMRLSAILLPVWIVFLFM
                     AFKTLRRK"
     gene            complement(3698..6841)
                     /gene="cusA"
                     /locus_tag="RN951_003290"
     CDS             complement(3698..6841)
                     /gene="cusA"
                     /locus_tag="RN951_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter permease
                     subunit CusA"
                     /protein_id="HDX2528247.1"
                     /translation="MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSD
                     VQVIIKTSYPGQAPQIVENQVTYPLTTTMLSVPGAKTVRGFSQFGDSYVYVIFEDGTD
                     PYWARSRVLEYLNQVQGKLPAGVSAELGPDATGVGWIYEYALVDRSGKHDLADLRSLQ
                     DWFLKYELKTIPDVAEVASVGGVVKEYQVVIDPQRLAQYGISLAEVKSALDASNQEAG
                     GSSIELAEAEYMVRASGYLQTLDDFNHIVLKASENGVPVYLRDVAKVQIGPEMRRGIA
                     ELNGEGEVAGGVVILRSGKNAREVIAAVKDKLETLKSSLPEGVEIVTTYDRSQLIDRA
                     IDNLSGKLLEEFIVVAVVCALFLWHVRSALVAIISLPLGLCIAFIVMHFQGLNANIMS
                     LGGIAIAVGAMVDAAIVMIENAHKRLEEWQHQHPDATLDNKTRWQVITDASVEVGPAL
                     FISLLIITLSFIPIFTLEGQEGRLFGPLAFTKTYAMAGAALLAIVVIPILMGYWIRGK
                     IPPESSNPLNRFLIRVYHPLLLKVLHWPKTTLLVAALSVLTVLWPLNKVGGEFLPQIN
                     EGDLLYMPSTLPGISAAEAASMLQKTDKLIMSVPEVARVFGKTGKAETATDSAPLEMV
                     ETTIQLKPQEQWRPGMTMDKIIEELDNTVRLPGLANLWVPPIRNRIDMLSTGIKSPIG
                     IKVSGTVLADIDAMAEQIEEVARTVPGVASALAERLEGGRYINVEINREKAARYGMTV
                     ADVQLFVTSAVGGAMVGETVEGIARYPINLRYPQSWRDSPQALRQLPILTPMKQQITL
                     ADVADIKVSTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQKAIAEKVQLKPGTSV
                     AFSGQFELLERANHKLKLMVPMTLMIIFVLLYLAFRRVGEALLIISSVPFALVGGIWL
                     LWWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAVPSLNNPQTFSEQKLDEA
                     LYHGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLLSLFI
                     IPAAYKLMWLHRHRVRK"
     gene            complement(6853..8076)
                     /gene="cusB"
                     /locus_tag="RN951_003291"
     CDS             complement(6853..8076)
                     /gene="cusB"
                     /locus_tag="RN951_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter periplasmic
                     adaptor subunit CusB"
                     /protein_id="HDX2528248.1"
                     /translation="MKKIALIIGSMIAGGIISAAGFTWVAKAEPPAEKTSTAERKILF
                     WYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSASGVRIDPTQTQNLGVKTATVTRG
                     PLTFAQSFPANVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGTPLLDLTIPDWVE
                     AQSEYLLLRETGGTATQTEGILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVI
                     TAFDLRAGMNIAKDNVVAKIQGMDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTL
                     TIRKWTLLPGVDAATRTLQLRLEVDNADEALKPGMNAWLQLNTASEPMLLIPSQALID
                     TGSEQRVITVDADGRFVPKRVAVFQASQGVTALRSGLAEGEKVVSSGLFLIDSEANIS
                     GALERMRSESATHAH"
     gene            complement(8092..8424)
                     /gene="cusF"
                     /locus_tag="RN951_003292"
     CDS             complement(8092..8424)
                     /gene="cusF"
                     /locus_tag="RN951_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter periplasmic
                     metallochaperone CusF"
                     /protein_id="HDX2528249.1"
                     /translation="MKKALQVAMFSLFTVIGFNAQANEHHHETMSEAQPQVISATGVV
                     KGIDLESKKITIHHDPIAAVNWPEMTMRFTITPQTKMSEIKTGDKVAFNFVQQGNLSL
                     LQDIKVSQ"
     gene            complement(8582..9955)
                     /gene="cusC"
                     /locus_tag="RN951_003293"
     CDS             complement(8582..9955)
                     /gene="cusC"
                     /locus_tag="RN951_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter outer
                     membrane channel CusC"
                     /protein_id="HDX2528250.1"
                     /translation="MSPCKLLPFCVALALTGCSLAPDYQRPAMPVPQQFSLSQNGLVN
                     AADNYQNAGWRTFFVDNQVKTLISEALVNNRDLRMATLKVQEARAQYRLTDADRYPQL
                     NGEGSGSWSGNLKGNTATTREFSTGLNASFDLDFFGRLKNMSEAERQNYLATEEAQRA
                     VHILLVSNVAQSYFNQQLAYAQLQIAEETLRNYQQSYAFVEKQLLTGSSNVLALEQAR
                     GVIESTRSDIAKRQGELAQANNALQLLLGSYGKLPQAQTVNSDSLQSVKLPAGLSSQI
                     LLQRPDIMEAEHALMAANANIGAARAAFFPSISLTSGISTASSDLSSLFNASSGMWNF
                     IPKIEIPIFNAGRNQANLDIAEIRQQQSVVNYEQKIQNAFKEVADALALRQSLNDQIS
                     AQQRYLASLQITLQRARALYQHGAVSYLEVLDAERSLFATRQTLLDLNYARQVNEISL
                     YTALGGG"
     gene            10112..10795
                     /gene="cusR"
                     /locus_tag="RN951_003294"
     CDS             10112..10795
                     /gene="cusR"
                     /locus_tag="RN951_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper response regulator transcription factor
                     CusR"
                     /protein_id="HDX2528251.1"
                     /translation="MKLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGD
                     YDLIILDIMLPDVNGWDIVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLVKP
                     FAFAELLARVRTLLRRGAAVIIESQFQVADLMVDLVSRKVTRSGTRITLTSKEFTLLE
                     FFLRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRGKIDNDFEPKLIQTVRGVG
                     YMLEVPDGQ"
     gene            10785..12227
                     /gene="cusS"
                     /locus_tag="RN951_003295"
     CDS             10785..12227
                     /gene="cusS"
                     /locus_tag="RN951_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) sensor histidine kinase CusS"
                     /protein_id="HDX2528252.1"
                     /translation="MVSKPFQRPFSLATRLTFFISLATIAAFFAFAWIMIHSVKVHFA
                     EQDINDLKEISATLERVLNHPDETQARRLMTLEDIVSGYSNVLISLADSQGKTVYHSP
                     GAPDIREFTRDAIPDKDAQGGEVYLLSGPTMMMPGHGHGHMEHSNWRMINLPVGPLVD
                     GKPIYTLYIALSIDFHLHYINDLMNKLIMTASVISILIVFIVLLAVHKGHAPIRSVSR
                     QIQNITSKDLDVRLDPQTVPIELEQLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTP
                     ITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIPEKK
                     MLNLADEVGKVFDFFEALAEDRGVELRFVGDKCQVAGDPLMLRRALSNLLSNALRYTP
                     TGETIVVRCQTVDHLVQVIVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLA
                     IVKSIVVAHKGTVAVTSDARGTRFVITLPA"
     gene            12377..14614
                     /gene="nrfB"
                     /locus_tag="RN951_003296"
     CDS             12377..14614
                     /gene="nrfB"
                     /locus_tag="RN951_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage adsorption protein NrfB"
                     /protein_id="HDX2528253.1"
                     /translation="MDWLLDVFATWLYGLKVIAITLAVIMFISGLDDFFIDVVYWVRR
                     IKRKLSVYRRYPRMSYRELYKPDEKPLAIMVPAWNETGVIGNMAELAATTLDYENYYI
                     FVGTYPNDPDTQRDVDEVCARFPNVHKVVCARPGPTSKADCLNNVLDAITQFERSANF
                     AFAGFILHDAEDVISPMELRLFNYLVERKDLIQIPVYPFEREWTHFTSMTYIDEFSEL
                     HGKDVPVREALAGQVPSAGVGTCFSRRAVTALLADGDGIAFDVQSLTEDYDIGFRLKE
                     KGMTEIFVRFPVVDEAKEREQRKFLQHARTSNMICVREYFPDTFSTAVRQKSRWIIGI
                     VFQGFKTHKWTSSLTLNYFLWRDRKGAISNFVSFLAMLVMIQLLLLLAYESLWPDAWH
                     FLSIFSGSAWLMTLLWLNFGLMVNRIVQRVIFVTGYYGLTQGLLSVLRLFWGNLINFM
                     ANWRVLKQVLQHGDPRRVAWDKTTHDFPSVTGDTRSLRPLGQILLENQVITEEQLDTA
                     LRNRVEGLRLGGSMLMQGLISAEQLAQALAEQNGVAWESIDAWQIPSSLIAEMPASVA
                     LHYAVLPLRLENDELIVGSEDGIDPVSLAALTRKVGRKVRYVIVLRGQIVTGLRHWYA
                     RRRGHDPRAMLYNAVQHQWLTEQQAGEIWRQYVPHQFLFAEILTTLGHINRSAINVLL
                     LRHERSSLPLGKFLVTEGVISQETLDRVLTIQRELQVSMQSLLLKAGLNTEQVAQLES
                     ENEGE"
     gene            14601..17573
                     /gene="nfrA"
                     /locus_tag="RN951_003297"
     CDS             14601..17573
                     /gene="nfrA"
                     /locus_tag="RN951_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage adsorption protein NfrA"
                     /protein_id="HDX2528254.1"
                     /translation="MKENNLNRVIGWSGLLLTSLLSTSALADNIGTSAEELGLSDYRH
                     FVIYPRLDKALKAQKNNDEATAIREFEYIHQQVPDNIPLTLYLAEAYRHFGHDDRARL
                     LLEDQLKRHPGDARLERSLAAIPVEVKSVTTVEELLAQQKACDAAPTLRCRSEVGQNA
                     LRLAQLPVARAQLNDATFAASPEGKTLRTDLLQRAIYLKQWSQADTLYNEARQQNTLS
                     AAERRQWFDVLLAGQLDDRILALQSQGIFTDPQSYITYATALAYRGEKARLQHYLIEN
                     KPLFTTDAQEKSWLYLLSKYSANPVQALANYTVQFADNRQYVVGATLPVLLKEGQYDA
                     AQKLLATLPANEMLEERYAVSVATRNKAEALRLARLLYQQEPANLTRLDQLTWQLMQN
                     EQSREAADLLLQRYPFQGDARVSQTLMARLASLLESHPYLATPAKVAILSKPLPLAEQ
                     RQWQSQLPGIADNCPAIVRLLGDMSPSYDAAAWNRLAKCYRDTLPGVALYAWLQAEQR
                     QPSAWQHRAVAYQAYQVEDYATALAAWQKISLHDMSNEDLLAAANTAQAAGNGAARDR
                     WLQQAEKRGLGSNALYWWLHAQRYIPGQPELALNDLTRSINIAPSANAYVARATIYRQ
                     RHNVPAAVSDLRAALELEPNNSNTQAALGYALWDSGDIAQSREMLEPAHKGLPDDPAL
                     IRQLAYVNQRLDDMPATQHYARLVIDDIDNQALITPLTPEQNQQRFNFRRLHEEVGRR
                     WTFSFDSSIGLRSGAMSTANNNVGGAAPGKSYRSYGQLEAEYRIGRNMLLEGDLLSVY
                     SRVFADTGENGVMMPVKNPMSGTGLRWKPLRDQIFFIAVEQQLPLNGQNGASDTMLRA
                     SASFFNGGKYSDEWHPNGSGWFAQNLYLDAAQYIRQDIQAWTADYRVSWHQKVANGQT
                     IEPYAHVQDNGYRDKGTQGAQLGGVGVRWNIWTGETHYDAWPHKVSLGVEYQHTFKAI
                     NQRNGERNNAFLTIGVHW"
     gene            17574..18464
                     /locus_tag="RN951_003298"
     CDS             17574..18464
                     /locus_tag="RN951_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4434 family protein"
                     /protein_id="HDX2528255.1"
                     /translation="MRKFIFVLLTLLLVSPFSFAMKGIIWQPQNRDSQVTDTQWQGLM
                     SQLRLQGFDTLVLQWTRYGDAFTQPEQRTLLFKRAAAAQQAGLKLIVGLNADPEFFMH
                     QKQSSAALESYLNRLLAADLQQARLWSAAPGITPDGWYISAEIDDLNWRSEAARQPLL
                     TWLNNAQRLISDVSAKPVYISSFFAGNMSPDGYRQLLEHVKATGVNVWVQDGSGVDKL
                     TAEQRERYLQASADCQSPAPASGVVYELFVAGKGKTFTAKPKPDAEIASLLAKRSSCG
                     KDTLYFSLRYLPVAHGILEY"
     gene            18647..19408
                     /gene="envY"
                     /locus_tag="RN951_003299"
     CDS             18647..19408
                     /gene="envY"
                     /locus_tag="RN951_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator EnvY"
                     /protein_id="HDX2528256.1"
                     /translation="MQLSSSEPCVVILTEKEVEVSVNNHATFTLPKNYLAAFACNNNV
                     IELSTLNHVLITHINRNIINDYLLFLNKNLTCVKPWSRLATPVIACHSRTPEVFRLAA
                     NHSKQQPSRPCEAELTRALLFTVLSNFLEQSRFIALLMYILRSSVRDSVCRIIQSDIQ
                     HYWNLRIVASSLCLSPSLLKKKLKNENTSYSQIVTECRMRYAVQMLLMDNKNITQVAQ
                     LCGYSSTSYFISVFKAFYGLTPLNYLAKQRQKVMW"
     gene            complement(19454..19530)
                     /locus_tag="RN951_003300"
     tRNA            complement(19454..19530)
                     /locus_tag="RN951_003300"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19494..19496),aa:Arg,seq:tct)
     gene            19773..20405
                     /gene="fimZ"
                     /locus_tag="RN951_003301"
     CDS             19773..20405
                     /gene="fimZ"
                     /locus_tag="RN951_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria biosynthesis transcriptional regulator
                     FimZ"
                     /protein_id="HDX2528257.1"
                     /translation="MKPTSVIIMDTHPIIRMSIEVLLQKNSELQIVLKTDDYRITIDY
                     LRTRPVDLIIMDIDLPGTDGFTFLKRIKQIQSTVKVLFLSSKSECFYAGRAIQAGANG
                     FVSKCNDQNDIFHAVQMILSGYTFFPSETLNYIKSNKCSTNSSTVTVLSNREVTILRY
                     LVSGLSNKEIADKLLLSNKTVSAHKSNIYGKLGLHSIVELIDYAKLYELI"
     gene            complement(20408..20923)
                     /gene="sfmF"
                     /locus_tag="RN951_003302"
     CDS             complement(20408..20923)
                     /gene="sfmF"
                     /locus_tag="RN951_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria assembly protein"
                     /protein_id="HDX2528258.1"
                     /translation="MRRVLFSCFCGLLWSSSGWAVDPLGTININLHGNVVDFSCTVNT
                     ADIDKTVDLGRWPTTQLLNAGDTTALVPFSLRLEGCPPGSVAILFTGTPASDTNLLAL
                     DDPAMAQTVAIELRNSDRSRLALGEASPTEEVDANGNVTLNFFANYRALASGVRPGVA
                     KADAIFMINYN"
     gene            complement(20934..>21446)
                     /locus_tag="RN951_003303"
     CDS             complement(20934..>21446)
                     /locus_tag="RN951_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415066.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX2528259.1"
                     /translation="VMFTVYVTSTPYDPLVTPVYTISFGGRVEVPQNCELNAGQIVEF
                     DFGDIGASLFSAAGPGNRPAGVMPQTKSIAVKCTNVAAQAYLTMRLEASAVSGQAMVS
                     DNQDLGFIVADQNDTPITPNDLNSVIPFRLDAAAAANVTLRAWPISITGQKPTEGPFS
                     ALGYLRVDYQ"
BASE COUNT         5261 a         5711 c         5381 g         5093 t
ORIGIN      
        1 tggctaaacg cgatcaaaaa agagtgcgtc caggctaaag cggaatctat agcgcatttt
       61 tctcgcttac catttctcgt tgaaccttgt aatctgctgg cacgcaaaat tactttcaca
      121 tggagtcttt atggatatca tttctgtcgc cttaaagcgt cattccacta aggcatttga
      181 tgccagcaaa aaacttaccc cggaacaggc cgagcagatc aaaacgctac tgcaatacag
      241 cccatccagc accaactccc agccgtggca ttttattgtt gccagcacgg aagaaggtaa
      301 agcgcgtgtt gccaaatccg ctgccggtaa ttacgtgttc aacgagcgta aaatgcttga
      361 tgcctcgcac gtcgtggtgt tctgtgcaaa aaccgcgatg gacgatgtct ggctgaagct
      421 ggttgttgac caggaagatg ccgatggccg ctttgccacg ccggaagcga aagccgcgaa
      481 cgataaaggt cgcaagttct tcgctgatat gcaccgtaaa gatctgcatg atgatgcaga
      541 gtggatggca aaacaggttt atctcaacgt cggtaacttc ctgctcggcg tggcggctct
      601 gggtctggac gcggtaccca tcgaaggttt tgacgccgcc atcctcgatg cagaatttgg
      661 tctgaaagag aaaggctaca ccagtctggt ggttgttccg gtaggtcatc acagcgttga
      721 agattttaac gctacgctgc cgaaatctcg tctgccgcaa aacatcacct taaccgaagt
      781 gtaattctct cttgccgggc atctgcccgg ctatttcctc tcagattctc ctgatttgca
      841 taaccctgtt tcagccgtca tcataggctg ctgttgtata aaggagacgt tatgcaggat
      901 ttaatatccc aggttgaaga tttagcgggt attgagatcg atcacaccac ctcgatggtg
      961 atgattttcg gtattatttt tctgaccgcc gtcgtggtgc atattatttt gcattgggtg
     1021 gtactgcgga ccttcgaaaa acgtgccatc gccagttcac ggctttggtt gcaaatcatt
     1081 acccagaata aactcttcca ccgtttagct tttaccctgc aggggattat cgtcaatatt
     1141 caggcggtat tctggctgca aaaaggcacc gaagcggcag atattctgac tacctgcgcg
     1201 cagttgtgga tcatgatgta tgcgctgctt tcagtcttct cgttgctgga tgttattttg
     1261 aatctggcgc agaaattccc ggcagcatct cagttaccgc tgaaagggat atttcagggg
     1321 attaaactga tcggcgcgat tctggtcggc attttgatga tctcgctgct gattggtcag
     1381 tcgccagcga ttctgatcag cggtcttggt gcaatggctg ccgtgctgat gttggtattt
     1441 aaagatccga ttcttggtct ggtggcaggt attcagcttt ccgcgaacga tatgctgaaa
     1501 ctgggcgact ggctggagat gccgaaatac ggcgcggatg gcgcggtgat cgatattggg
     1561 ttaaccaccg tcaaagtgcg taactgggac aataccatta ccactattcc cacctggtct
     1621 ctggtttctg actcctttaa aaactggagc gggatgtcag catctggcgg gcgacgtatt
     1681 aagcgcagta tcagtattga tgtcaccagt attcgttttc ttgatgaaga cgaaatgcaa
     1741 cgtctgaata aagcgcattt gttaaagcct tatttaacca gccgccatca ggaaattaat
     1801 gagtggaatc gccagcaagg ttctacggag tcggtattaa atctgcgccg aatgaccaat
     1861 attggaacct ttcgtgccta tctgaacgaa tatctgcgta accatccgcg gattcgtaaa
     1921 gatatgacct taatggtacg ccaactggct ccaggtgata acggtttacc gctcgagatc
     1981 tacgcgttta ctaacaccgt ggtgtggctg gaatatgaaa gcattcaggc tgatatattc
     2041 gatcacatat ttgcgattgt cgaagagttt ggtctgcgac ttcatcagtc gccaaccggc
     2101 aatgatattc gctctctggc gggtgcattt aagcagtaat taaaaaaacc gctctcatcg
     2161 aatggatgag agcggtttcg gatggttgac atcgttttgt cggatgtagc gtgaatgcct
     2221 tatttccgac gcagcgtttt aaatgccata aacaggaata caatccacac cggcagcagg
     2281 atcgctgaca agcgcatatc atccatcgtg cacatcagca gcaaaatcat gccgaggaag
     2341 gcaatgcaga gatagttgcc gaacggatag agcagcgcct taaactgtgt ttcacgcccc
     2401 tgacgtcgca tcgctgcacg aaaacgcaga tgcgccagac agatcataat ccagttcaac
     2461 agcagcgttg ctaccaccag cgccatcagc agaccaaacg ctttttgcgg cagcagatag
     2521 ttgattaaca ccaccagcga agtgatcgct ccggaaagca tcagcgagtt aatcggcaca
     2581 ccgcgacggc tgacgcgagt caaaaacttc ggcgcattac cctgcacaga aaggccaaac
     2641 agcatgcggc tgttagagta aaccccgctg ttatacactg acagcgatgc taccagaatg
     2701 acgaagttca gcgcagaagc taccacgttg ctgtcgagat tatggaaaat catcacaaac
     2761 gggctactgt tggatttcac ttccacccac ggatagagcg ccagtaaaac caccagtgaa
     2821 ccgatgtaaa acagcaggat gcgatacacc acctgattta ccgcttttgg aatgcttttt
     2881 tccggatcgc gcgcttcagc ggcagtaatc ccaatcagct ccagaccgcc gaaggagaac
     2941 ataattaccg ccagcgacaa aatcagccca ttccagccgg tggcgaagaa accaccgtag
     3001 cgccagaggt tgtcgatact ggctttctcg ccgccgtgac cagaaaacag cagccacagg
     3061 ccaaagccga tcataccgat gattgccagc actttaatca acgcaaacca gaactcggtt
     3121 tcgccatata agcgcacgtt caccaggtta acggcgttga tgataataaa gaaggcggca
     3181 gcccaaatcc acgttggaac atccgggaac cagtactgca tatagatgcc cgcagcggtc
     3241 agctctgcca ttcccaccag cacgaacatt acccagtagt tccagccaga gaggaagccc
     3301 gcaaacggtc cccagtattt ataggcaaag tgggcaaatg aaccggatac cggctcctca
     3361 accaccattt cgccaagctg gcgcataatc aggaaagcga tgatcccggc gacgccgtag
     3421 cccagcaata cagccggacc cgccatctga atcgccgggc caatgccaag aaacagacca
     3481 gtaccaattg cgccacccaa cgcaatcagt tgaatatgac ggttatgtaa tccgcgatga
     3541 agcgtcggct cttgattcga cgcagtatct tccgatacgg ttgacgcgtt tttcacgcct
     3601 ttcccctgtg tgtctttttt gttgaggggc accttttaac atttagtgcc catcgtcgca
     3661 agacacaatc cacacggtta aacggggtat cctgctttta tttccgtacc cgatgtcggt
     3721 gcagccacat cagcttatac gccgccggga taataaacag cgacagcaaa ggtgcggtga
     3781 tcatgccgcc aatcatcggc gcggcaatcc ggctcatcac ctctgaacca gcccccgttc
     3841 cccacagaat cggcagcaga ccggcgataa tcaccgccac cgtcatcgct ttcgggcgca
     3901 cgcgcaggac cgcgccgtga tataacgcct catccagctt ctgctcgctg aatgtttgtg
     3961 gattattcaa cgacggcacg gcctctatgg cgtgacgtaa atacatcagc atcaccacgc
     4021 caaattcggc ggcgaccccg gcgagggcga taaagccagt gcccgtcgcc acggaaagat
     4081 gaaagcccat ccaccacagc aaccagatgc cgcccaccag cgcaaacggt acgctgctga
     4141 taatcagcaa cgcttcgccc acccgacgga acgccagata caacagcacg aagataatca
     4201 tcaacgtcat cggcaccatg agtttaagct tatggttggc gcgctccagt agctcgaact
     4261 gcccggagaa tgccacgctg gtgcccggtt ttaactgcac tttttcagct atcgcttttt
     4321 gcaaatcgtg aaccaccgac accatgtcac gatcgcgggc atcgatataa atccagctcg
     4381 tcgggcgcgc attctcggtt ttcagcatcg acggtccggt agagacttta atgtcggcca
     4441 cgtctgccag ggtgatttgc tgcttcatcg gcgtcaggat cggcagctgg cgcagtgcct
     4501 gcggactatc gcgccagctt tgcggataac gcagattaat tggataacgg gcaatccctt
     4561 ccaccgtttc gccaaccatc gccccgccca ccgcagaagt cacaaacaac tgcacatccg
     4621 ccaccgtcat accgtaacgt gcggcttttt cacggttaat ctcaacgttg atatagcgcc
     4681 caccttccag ccgctcggca agcgcagaag ctacgcctgg caccgttcgc gctacttctt
     4741 caatttgctc agccatcgcg tcgatatccg ccagcacagt gccggaaact ttaatgccga
     4801 tggggctttt aatgccggtt gagagcatat cgatacggtt acgaattggc ggcacccaca
     4861 gattcgccag ccccggcagc cgcacggtgt tatccagttc ctcaatgatt ttgtccatcg
     4921 tcatgcctgg ccgccactgc tcctgcggct taagctggat ggtcgtttct accatctcca
     4981 gcggagcaga atcggtggcg gtttccgctt tcccggtttt gccaaatacc cgcgccactt
     5041 caggtacgct cataattagc ttgtcggttt tttgcagcat actcgccgcc tctgctgcgg
     5101 aaatccccgg cagcgtcgat ggcatataca acaagtcgcc ttcattgatc tgcggtaaaa
     5161 attccccgcc aactttattg agcggccaga gaaccgtcag caccgaaagc gccgccacca
     5221 gcagcgtggt tttcggccag tgcagtactt tcagcaacag cggatgataa acacgaatca
     5281 aaaagcgatt gagcgggtta ctgctttccg gcggaatttt gccacggatc cagtagccca
     5341 tcaggatcgg gatcactacg atcgccagca gcgccgcacc cgccatcgca tacgttttgg
     5401 tgaacgccaa cgggccaaac agacgccctt cctgcccttc cagggtgaag atcgggataa
     5461 acgacaacgt gataatcagc agactgataa atagcgccgg ccccacttca acagacgcat
     5521 cggtgatcac ctgccagcgc gttttattat ccagcgtggc gtcaggatgc tggtgctgcc
     5581 actcttccag ccgtttatgc gcattctcga tcatgacgat agcagcatcg accatcgccc
     5641 cgacggcaat cgcaatgcca cccaacgaca taatattggc attcagtccc tggaagtgca
     5701 tgacaataaa agcaatacac aaccccagcg gcaacgaaat aatcgccacc agcgccgagc
     5761 gcacatgcca gagaaacagc gcacagacta ccgccaccac aataaactct tccagcaact
     5821 tgccgctgag gttgtcgatg gcgcggtcaa tgagctggct gcgatcgtat gttgtaacta
     5881 tctccacgcc ttccggcaga ctacttttca gcgtttccag tttgtccttc acggcggcga
     5941 tcacttctcg ggcgtttttg ccggatcgca ggatcaccac cccgcccgcc acttcgcctt
     6001 cgccgtttag ttcggcaatg ccccggcgca tctccgggcc aatctggacc ttcgcaacat
     6061 cgcgcagata aacgggcacg ccattttcac tggcttttaa aacgatgtga ttaaagtcgt
     6121 cgagcgtttg cagatagccg ctggcgcgca ccatatattc cgcttccgcc agttcgatcg
     6181 acgaaccgcc cgcttcctgg tttgaagcat ccagcgcgct ttttacttcg gcgagactga
     6241 tgccatactg cgccaggcgc tggggatcga taaccacctg atactctttc accacaccgc
     6301 ccaccgacgc cacttccgca acgtcaggga tggttttcag ctcatatttg agaaaccagt
     6361 cctgtaatga gcgtaaatcg gccagatcgt gcttaccgct gcgatccacc agtgcatatt
     6421 catagatcca gccaacaccc gtggcatctg gccccagctc ggcgctgact cccgcaggca
     6481 gcttaccctg tacctggttg aggtactcca gcacccgcga acgcgcccag tacggatcgg
     6541 tgccatcttc gaaaatgaca tacacataag agtcgccaaa ctgtgagaaa ccgcgcacag
     6601 tcttcgcgcc aggcaccgac aacatggtgg tggttagcgg ataagtcacc tgattttcaa
     6661 cgatttgtgg tgcctgaccg ggatagctgg ttttaataat aacctgcaca tcggagagat
     6721 ccggcagcgc atccactggc gtattaatga tggtccaggt gccccagatg ctcagaaaca
     6781 acgcgcccat cagcaccaaa aaacggttcg ccaccgagcg acgaataatc cattcaatca
     6841 ttggttattc cctcaatgcg catgggtagc actttcagag cgcatccgct ccagtgcgcc
     6901 agaaatattg gcttcggaat caatcaggaa caggccgctg gaaaccacct tttcaccttc
     6961 cgccagacca gagcgtaatg cggtgacgcc ttgcgatgcc tggaaaacag caacgcgttt
     7021 cggtacaaag cgcccgtcgg catcaacggt aatcacccgc tgttcgctgc cggtatcaat
     7081 cagcgcttgt gacggaatga gcagcatcgg ttcgctggcg gtgttgagtt gcaaccaggc
     7141 gttcatgccc ggttttagcg cctcgtcggc gttgtcgact tccagacgca gctgcagcgt
     7201 gcgggtcgcg gcatccacgc caggtagcag cgtccatttg cggatggtga gtgttttatc
     7261 cggtcgcgcc ggaacggtga gggtaaactg cgaggcatct ttcaccagcc aggcgataga
     7321 ctccgggatc gcagcagtga cccacaccgg gtccataccc tgaattttcg ctaccacgtt
     7381 atctttggcg atattcattc ccgcgcgcag atcaaacgcg gtgatcacgc catcaatggg
     7441 cgctttgagc gtaaagcgag tctggatttt ttgcgtggcg atcaggcggc gaatatccgc
     7501 ctccggcatt cccgccagtc gcagccgctc aagaatgcct tcagtctggg tcgccgtacc
     7561 gccggtttcg cgcagcagta aatactcact ctgcgcttcc acccagtcag gaatggtcag
     7621 gtcgagaagc ggtgtgccct tttgtacttt atcgcccacg gtaagcggat acaccttgtc
     7681 gataaacccg gcagcgcgag cctgcacaat ggcatactga tactcgttgt aactgacatt
     7741 cgccgggaaa ctctgggcaa aagtcagcgg tccgcgcgtg acggtagccg ttttcacccc
     7801 cagattctgc gtctgagtcg ggtcaatgcg cacaccagac gcagaactct cttcatcggc
     7861 atatttcggc accagatcca tatccataaa cggcgattta cctggtttat cgaaccgcgt
     7921 attgggatac attgggtcgt accagaataa gattttacgt tctgcggtcg acgttttttc
     7981 tgcaggcggt tccgcctttg caacccaggt aaaacctgcc gcagaaataa taccgcccgc
     8041 gatcatgctg ccgataataa gcgcgatttt tttcatctca ttaaacctgg gttactggct
     8101 gactttaata tcctgtaata aagaaaggtt gccctgctgg acaaaattaa acgccacttt
     8161 gtcgccggtt ttaatttcac tcattttcgt ctgcggggtg atggtaaagc gcatggtcat
     8221 ctccggccag ttcacggcag caatcggatc gtgatggatg gtgatttttt tgctttccag
     8281 atcaataccc tttaccacgc cagtggcgct aataacctgt ggttgtgctt cgctcatggt
     8341 ttcatgatga tgttcgttag cctgggcatt aaagccaata acggtaaaca gactgaacat
     8401 tgcgacttgc agtgcttttt tcatttattc tctcctggag ttaaaagtca tactctaaat
     8461 aattcgagtt gcaggaaggc gacaagcgag tgaatcccca ggagcttaca taagtaagtg
     8521 actggggtga gcgaacgcag acgcagcaca tgcaacttga agtatgacga gtatattgct
     8581 gtcaaccgcc accaagtgcg gtatacaaag aaatttcgtt aacctgacgg gcataattca
     8641 gatcaagtaa agtttgtcgg gttgcaaata aagaacgctc ggcatccagc acttccagat
     8701 aacttactgc gccgtgctga tataatgccc gcgcccgttg caaagtaatt tgcagcgatg
     8761 ccagataacg ctgctgggcg ctaatttgat cgttcaggct ttgacgtaat gccagcgcat
     8821 ctgccacttc tttaaaggcg ttctggattt tctgttcata attcaccacc gactgctgct
     8881 ggcgaatttc ggcgatatcc agattggcct ggttgcgtcc ggcattaaaa atggggatct
     8941 caattttggg tataaaattc cacatcccgc tgctggcgtt aaataatgac gatagatcgc
     9001 tactggcggt cgatattccg ctggtcaggc ttatagacgg aaaaaatgcc gcgcgtgcag
     9061 cgccaatatt ggcattagcc gccattaacg cgtgttcagc ttccataata tccgggcgct
     9121 gcaataagat ttgcgacgac aatcccgccg gtaatttaac gctttgcagg ctgtcgctgt
     9181 ttactgtctg cgcttgcggc agcttgccgt agcttcccag caacagttgc aatgcattat
     9241 tcgcctgcgc cagttccccc tgacgtttag cgatgtcgct gcgggtactt tctatcaccc
     9301 cgcgagcctg ttccagcgcc agaacattac tgctacctgt caacagttgt ttttcgacaa
     9361 acgcatatga ctgctgataa ttacgcagcg tttcttcggc tatttgcaat tgcgcatacg
     9421 ccagttgctg attgaaatag ctttgcgcga cattagaaac cagcagaata tgcaccgcgc
     9481 gctgagcttc ctcagtggct aaataatttt gtcgctcggc ttcgctcatg ttctttaagc
     9541 gaccgaaaaa atcgaggtca aagctggcgt taaggccggt cgaaaactcc cgtgtcgtgg
     9601 cggtattccc tttaagatta ccgctccagc tgccgctgcc ctcgccattg agctgtgggt
     9661 agcggtcggc atcggtcaga cgatattgcg cccgtgcctc ctgcactttc agcgtcgcca
     9721 tgcgcaaatc ccgattattc accagcgcct cgctaatcag cgtcttcacc tgattatcaa
     9781 caaaaaaggt gcgccagccc gcgttctgat agttatctgc tgcgttaacc aggccgttct
     9841 ggctgagtga gaactgctgc ggcacgggca ttgccggacg ctgataatcc ggtgccagtg
     9901 aacaaccggt tagcgcaagg gccacacaaa atggcagaag tttacaagga gacataggct
     9961 cataatttct ggtgatttta tgccgccaac tttactcgcc aggctctgat tttccggtga
    10021 cagaaaaatg acaaaattgt cattttgcca ataagcgatt gccatctgat cccgctactc
    10081 tagaattgcc cgggcaacat gcggaggaaa tatgaaactg ttgattgtcg aagatgaaaa
    10141 gaaaaccgga gaatacttga ccaaagggtt aaccgaagcc ggttttgtgg tcgatttggc
    10201 cgacaacggg ctgaatggct accatctggc gatgaccggt gattatgatc tgataatcct
    10261 cgatattatg ctgccggacg tgaacggctg ggatatcgtg cgcatgttac gctccgccaa
    10321 taaagggatg ccgattctgt tgcttaccgc gcttggcacc attgaacatc gcgtcaaggg
    10381 gctggagttg ggggcagatg actacctggt gaagccattc gcttttgctg aactgctggc
    10441 gcgggtgcgc acattactgc ggcgcggggc ggcggtgatt atcgaaagtc agtttcaggt
    10501 tgccgatttg atggtcgatc tcgtcagccg caaagtcacc cgcagcggca cgcgcatcac
    10561 tttgaccagt aaagagttta ctctgctgga gttcttcctt cgccatcagg gcgaagtgct
    10621 gccccgctcg cttatcgcct cgcaggtatg ggacatgaat tttgacagcg ataccaatgc
    10681 tattgatgtg gcggtgaagc ggctgcgcgg caaaatcgac aacgactttg agccgaagct
    10741 aattcagacc gtgcgcggcg tgggttacat gcttgaggtg ccggatggtc agtaagccat
    10801 ttcagcgccc gttttcgctg gcaacccgcc tgaccttttt tatcagcctg gccaccatcg
    10861 cggcgttttt cgcctttgca tggatcatga tccactcagt aaaagttcat tttgccgagc
    10921 aggatattaa tgatttaaaa gagattagcg ccacccttga acgggtacta aatcaccctg
    10981 acgaaacgca agcccgacgc ttaatgacgc tggaagatat cgtcagtggt tattccaatg
    11041 tgttgatttc cctggcagat agtcagggta aaacggtgta tcactccccc ggtgcgccgg
    11101 atatccgcga gtttacgcgt gacgccatac ccgataaaga cgctcagggt ggcgaggtgt
    11161 atctcctttc cggcccgacg atgatgatgc caggccacgg tcacgggcat atggaacaca
    11221 gcaactggcg gatgattaac ttgccggttg gcccgttggt ggacggcaaa ccgatttata
    11281 cgctctacat cgcgctttcg atcgattttc atcttcatta cataaatgat ttgatgaata
    11341 aacttattat gaccgcatcg gtaatcagca tcctgatcgt ctttatcgta ctgttggcgg
    11401 tacataaagg tcacgcgccg atccgcagcg tcagccgtca aatccagaat attacctcga
    11461 aagatctcga cgttcgcctc gacccgcaga ccgtgcccat tgagctggaa cagctggtac
    11521 tgtcgttcaa ccatatgatc gagcgtattg aggatgtctt tacccgccag tccaatttct
    11581 cagcggatat cgctcacgaa attcgcacac caattacgaa tctcataacg caaaccgaaa
    11641 tcgccctcag ccagtcgcgc agccagaagg agctggaaga tgtgctctac tctaatctcg
    11701 aagagctgac gcgaatggcg aaaatggtca gcgatatgct gtttctcgct caggccgata
    11761 acaaccagct aatccccgaa aagaaaatgc tcaacctggc ggatgaagtc ggcaaagtgt
    11821 tcgatttttt cgaggcgtta gcggaagatc gcggcgtgga gttgcggttt gttggcgaca
    11881 agtgtcaggt cgcgggcgat ccgctgatgc tgcgtcgggc gctaagcaac ctgctttcga
    11941 acgccctgcg ttatacgcca accggagaga caattgtagt gcgctgtcag acggtcgatc
    12001 acctggtgca agttatcgtc gaaaaccccg gtacgcccat tgcgcccgag cacttaccgc
    12061 gattgtttga ccgtttctat cgcgttgacc cctcccgcca gcgaaaaggt gaaggtagcg
    12121 gtattggcct ggcgatagtg aaatcgattg ttgtcgcgca taaaggcacg gttgcggtaa
    12181 cgtcggatgc gcgggggaca aggtttgtta tcacattacc cgcttaatcc ttcagcaaac
    12241 ggcaactttt ataaccagtg taaaaataac gtgccgcaat agtcatacct attaatggta
    12301 aaaagctgtc acaattcata aaaaacctta atatacgcca ccctaaacat aaccagcgtt
    12361 aatgtaaggt ttttgtgtgg actggcttct tgatgttttt gctacctggc tctacggctt
    12421 aaaagtaatc gcgataacgt tagcggtcat catgttcatc agcgggctgg acgatttttt
    12481 tattgatgtc gtctactggg tacgccgcat taaacgcaag ttgagtgttt atcgccgcta
    12541 cccgcgaatg agttaccgcg aactgtataa accagatgaa aaaccgttag cgattatggt
    12601 tccggcgtgg aatgaaacgg gcgtcatcgg caatatggcc gagctggcgg cgaccacgct
    12661 cgactacgaa aactattata tctttgttgg cacctacccc aacgaccccg atactcagcg
    12721 tgatgttgac gaagtgtgcg ctcgcttccc gaatgtgcat aaggtagtct gcgcgcgtcc
    12781 tggccccacc agcaaagccg actgtctgaa caacgtgctg gacgccatca cccaatttga
    12841 gcgtagcgcc aatttcgctt ttgctggttt tattctgcat gacgccgaag atgtgatttc
    12901 accgatggaa ttgcgtctgt tcaactatct ggtcgagcgt aaagatctga ttcagatccc
    12961 ggtgtatccg ttcgaacgcg aatggacgca cttcaccagc atgacttaca ttgatgagtt
    13021 ttcagagctg catggcaaag atgttccggt gcgtgaagcc ctcgccggac aagtgcccag
    13081 cgcaggcgtc ggcacctgtt tcagccgccg cgccgtgacc gcactgttag ctgacggtga
    13141 cggtattgct ttcgacgtgc agagtcttac tgaagattac gacattggct tccgcctgaa
    13201 agaaaaaggt atgacggaaa tttttgtccg ttttccggtg gtggacgaag ccaaagaacg
    13261 cgagcagcgt aaatttttac agcacgcgcg gacatcaaac atgatctgcg tgcgcgaata
    13321 tttccccgat accttttcga ctgcggttcg acaaaaatcc cgctggatca tcggcattgt
    13381 tttccaaggc tttaaaaccc ataaatggac ctccagcctg acgctgaact actttctctg
    13441 gcgcgaccgc aaaggggcaa tcagtaactt tgtcagcttc ctcgcgatgc tggtgatgat
    13501 ccagcttttg ctgttgctgg cgtatgaaag tttgtggccc gatgcctggc atttcctttc
    13561 tattttcagc ggcagcgcat ggttaatgac cctgctgtgg ctaaactttg gtttgatggt
    13621 taaccgcatc gtgcagcggg tgattttcgt tactggctac tacggcctga cgcaggggct
    13681 gctttccgtc ctgcgtcttt tctggggcaa cctgattaac ttcatggcca actggcgcgt
    13741 gctaaaacag gtacttcaac acggcgatcc acgtcgcgtg gcgtgggata aaacaacgca
    13801 tgacttcccc agcgtgactg gcgatacccg ctcgttgcgc ccgttaggtc aaattctgct
    13861 ggaaaatcag gtcatcactg aagaacaact cgatacagca ctgcgtaatc gcgtcgaagg
    13921 tctacgcctg ggcggttcaa tgctgatgca ggggctgatt agcgccgagc agctggcaca
    13981 ggcgctggca gagcaaaacg gcgtggcgtg ggaatccatc gatgcctggc agatcccttc
    14041 ctcgctgatt gccgaaatgc cggcctccgt ggcgctgcat tatgcggtac tgccgctgcg
    14101 tctggaaaat gacgagttaa ttgtcggcag tgaagatggt attgacccgg tttcgctggc
    14161 ggccctgacg cgtaaagtcg gacgcaaagt gcgttacgtc attgttctgc ggggacaaat
    14221 tgtcacaggg ttacgtcact ggtatgcacg ccgacgcggt cacgatccgc gggcaatgtt
    14281 gtacaatgcg gttcagcatc agtggctcac ggaacagcag gccggtgaaa tctggcggca
    14341 atatgtgccg catcagttcc tgttcgccga aatactgacc acgctcggtc atattaatcg
    14401 ttcagcaatt aacgtgttgt tattgcgcca tgaacgcagt tctctgccgc tcggcaagtt
    14461 tttggtcacc gaaggcgtta tcagccagga aacgttggat cgcgtcctga caattcaacg
    14521 cgaattacaa gtttcgatgc aatcactatt actcaaagca ggtttaaaca cagaacaggt
    14581 tgcgcaactg gagtccgaaa atgaaggaga ataaccttaa tcgcgtcatc ggatggtctg
    14641 gtttactgct gacgtcttta ttgagtacca gcgcactcgc agacaatatc ggcaccagcg
    14701 cagaagagct ggggctgagc gattatcgcc attttgttat ttatccccgt ctcgataaag
    14761 cgctgaaggc acagaaaaat aacgacgaag caaccgccat ccgcgaattt gaatatatac
    14821 accagcaggt gccggataat attccgctga ctttatacct tgcggaagcc tatcgccatt
    14881 ttggtcatga tgaccgggcg cggctgttgc ttgaggatca actgaaacgt cacccaggag
    14941 atgcccgact tgagcgcagt ctggcggcta ttccggttga agtgaaaagc gttacgacag
    15001 ttgaagaact gcttgcccag caaaaagcgt gcgatgctgc gccgaccctg cgttgtcgca
    15061 gtgaagtcgg gcagaatgcc ctgcggctgg cacagttacc tgtcgccaga gcgcaactga
    15121 acgatgcgac gtttgctgca tcgccggaag gaaaaacgct gcgaaccgat ctgctgcaac
    15181 gggcaatcta cctgaaacaa tggtcccagg cagatacgct atacaatgaa gcacgccagc
    15241 agaacacatt aagcgcggca gaacgccgtc agtggtttga cgtgcttctt gccgggcagc
    15301 tggacgatcg gatcctggca ctgcaatcac aggggatctt caccgatcct cagtcatata
    15361 ttacttacgc gaccgcgctg gcttatcgtg gcgaaaaagc acgcctccag cattatctca
    15421 ttgaaaataa gccactattt accacggacg cacaagagaa aagttggctc tatctgttat
    15481 ctaaatacag cgctaacccc gttcaggcgt tggcgaatta tacggtacag tttgccgaca
    15541 accgccagta tgttgttggc gcgacgctac cggtgctgtt aaaagaaggt cagtacgacg
    15601 cagcgcaaaa actgctcgcc accctccccg ccaatgaaat gcttgaggag cgttatgctg
    15661 tcagcgtggc gacccgtaac aaggctgaag ctctgcgtct ggcacgattg ctgtatcagc
    15721 aagaaccggc aaatcttacc cgcctggatc aactaacctg gcaactgatg cagaacgagc
    15781 agtcacgcga agctgccgat ttattgctgc aacgctatcc tttccagggc gatgcgcgtg
    15841 tcagccagac tttaatggcg cgactggcgt ctctgctgga aagtcatcct tacctggcaa
    15901 cgccggcgaa ggtggcgatt ttatcgaaac ccttaccgct ggcggagcaa cgtcagtggc
    15961 aaagtcagtt gccgggtatt gcagataatt gcccggcaat agttcgcttg ctgggcgata
    16021 tgtcgccttc ctacgatgcc gccgcctgga accgtctggc aaagtgttat cgggacacgc
    16081 tacccggtgt ggcgttgtat gcatggcttc aggccgaaca acgacaaccg agcgcctggc
    16141 aacatcgtgc ggtagcctat caggcgtatc aggttgagga ctacgccacc gcactggcgg
    16201 cctggcagaa aatcagtctt cacgacatga gcaatgagga tctgcttgct gctgccaata
    16261 ccgcccaggc ggcaggaaat ggtgcggctc gcgatcgctg gctacaacag gcagaaaaac
    16321 gtggactggg aagcaatgcc ctctactggt ggctgcatgc gcaacgttac attcctggtc
    16381 agccggaact cgcactgaac gatctcacgc gctcaatcaa tattgcgcct tctgccaacg
    16441 cttacgttgc gcgggcgaca atttatcgcc aacgtcataa tgtcccggcc gcggtgagtg
    16501 atttgcgcgc cgcgctggaa ctggaaccga ataatagcaa cacccaggca gcgcttggtt
    16561 acgccttgtg ggatagcggt gatatcgcac agtcgcggga aatgctcgaa ccggcgcata
    16621 aagggcttcc ggacgatccg gcactgatcc gacaactggc ctacgtgaac cagcgtctgg
    16681 atgacatgcc tgcgacgcag cactacgccc ggctggtgat tgatgacatt gataatcagg
    16741 cgctgataac cccactgacc ccagaacaaa atcaacaacg cttcaatttc cgccgtttgc
    16801 atgaggaggt cggtcgccgc tggacgttca gtttcgattc ttccatcggc ttgcgttccg
    16861 gcgcaatgag taccgctaac aataatgtcg gcggcgcagc gccagggaaa agctatcgta
    16921 gctacggaca actggaagcc gagtaccgca tcggacgcaa tatgctgctg gaaggcgacc
    16981 tgctctcagt ttatagccgc gtctttgccg ataccggaga aaacggggtg atgatgccgg
    17041 tgaaaaatcc gatgtccggc accggtctgc gctggaagcc gctgcgcgat cagatctttt
    17101 tcatcgccgt cgaacagcag ttgccgctga acggccaaaa tggcgcatcc gataccatgc
    17161 tgcgcgccag cgcctcattc tttaatggcg gcaaatacag cgacgaatgg cacccgaacg
    17221 gttcaggctg gtttgcccaa aacctgtacc tcgatgcggc gcaatatatc cgccaggata
    17281 ttcaggcgtg gacggcagat tatcgcgtca gctggcatca gaaggtagct aacggacaga
    17341 ctattgagcc ttacgctcac gttcaggaca acggctatcg tgataaaggc actcagggcg
    17401 cgcagcttgg cggagtcggg gtccgctgga atatctggac cggcgagacg cactacgacg
    17461 cctggccgca caaagtcagt ctcggcgtcg agtatcaaca tacctttaag gcgattaatc
    17521 aacgtaacgg agagcgcaac aacgcgtttc tcaccattgg agtgcactgg taaatgcgta
    17581 agttcatttt cgtattgctg acactgcttt tggtcagccc tttttccttt gcgatgaaag
    17641 gtattatctg gcaaccacaa aaccgagata gtcaggttac cgatacccag tggcaggggc
    17701 tgatgagtca gttacgtttg caaggcttcg atacccttgt tttgcaatgg acccgttacg
    17761 gcgatgcatt tacccagcca gaacagcgca cgttattgtt taagcgggcc gcagctgcgc
    17821 aacaggctgg tctgaagctt attgtcgggc tgaacgccga tccggaattt tttatgcacc
    17881 agaaacagtc gtccgcagcg ctggaaagct atcttaatcg cctgctggct gccgatctcc
    17941 agcaagccag attatggagc gccgcgcctg gcataacgcc ggatggctgg tacatcagcg
    18001 cggaaattga cgacctgaac tggcgcagcg aagccgcccg tcagcctttg ctaacatggt
    18061 taaacaacgc gcagcggctg attagcgatg tttcagcaaa accggtttat atcagtagtt
    18121 ttttcgccgg aaacatgtcg cccgatggct atcgccaact gctggaacac gttaaagcaa
    18181 ccggcgttaa tgtctgggta caggatggca gcggcgtgga taaactgacc gctgaacagc
    18241 gtgaacgtta tttacaggcc agcgccgatt gccaaagtcc cgcccctgcc agcggcgttg
    18301 tttatgaact ttttgtcgcc ggcaaaggca aaacctttac agcgaaaccg aaaccggacg
    18361 cagaaattgc ctcgctgtta gcgaaacgtt cctcttgcgg taaagacact ctctatttct
    18421 ctctgcgcta tttgcccgtc gcgcacggca ttctcgagta ttaaatctcc tccaggtaag
    18481 tcgggtacga cctggcttac ctctttcgct ctcatcagaa ttccatcaag attaattgct
    18541 aaaaagcgtg ctaaagaaag aagatcgtta tcggcgaacg ggccgatcac tcatgcagga
    18601 agcatagatc ctttgagcgg agtttctgat atctgaggag tgcgaaatgc aattgagcag
    18661 cagtgaacct tgcgtggtga tcctgaccga aaaagaggta gaggtaagcg tcaataacca
    18721 tgctacgttt acccttccga aaaactacct ggccgccttc gcgtgcaaca ataacgtcat
    18781 tgaactctca acgttaaatc acgtattaat cacccacatc aaccgtaaca tcatcaacga
    18841 ttatctgttg tttttaaata agaacttaac ctgtgtaaag ccctggtcgc ggctggcaac
    18901 cccggttatc gcttgtcata gccgtacacc ggaagtgttc cggctagccg ccaaccacag
    18961 caagcagcaa cccagcagac cctgcgaagc ggagttgacg cgcgcattgc tttttaccgt
    19021 attgtctaac tttcttgagc aatcgcggtt tattgcccta ctgatgtata tcttacgcag
    19081 cagcgtccgc gacagcgtct gccgcattat tcaaagcgat attcagcatt actggaatct
    19141 gcgaattgtc gccagttcgc tatgtttaag ccccagcctg ctcaaaaaga aattaaaaaa
    19201 cgaaaatacc agctatagcc agattgtcac agagtgtcgt atgcgttacg ccgtacagat
    19261 gttattgatg gataacaaaa atatcactca ggtggcgcaa ttatgtggct atagcagcac
    19321 gtcgtacttt atctctgttt ttaaggcgtt ttacggcctg acaccgttga attatctcgc
    19381 caaacagcga caaaaagtga tgtggtgaag ggcaaagcgg aaacggataa gacgggcata
    19441 aatgaggaag aaatggcgcg ccctgcagga ttcgaacctg cggcccacga cttagaaggt
    19501 cgttgctcta tccaactgag ctaagggcgc gttgataccg caatgcggtg taatcgcgtg
    19561 aattatacgg tcaacccttg ctgagtcaat ggcttttgat ctggttgctg aacaagtgaa
    19621 cgaccgcgtc tgattttctg atttatttcg ctatagcggc aaacaaacgc acaccgctgc
    19681 gcgtctgaat caagaaaacc cgtattttca tgtatcaaag tacaatttcc cgacctaacg
    19741 gaaaattgtc cgctcctatg agactggtaa ctatgaaacc aacgtcggtg atcattatgg
    19801 atactcatcc tatcatcaga atgtctattg aagttctgtt gcaaaaaaac agtgaattgc
    19861 agattgtcct gaaaacggat gattatcgca taaccatcga ttatctccga acccgtcctg
    19921 ttgatttaat cattatggat atagacttgc ccggaacaga cggttttacc ttcctgaaaa
    19981 ggatcaaaca aatccagagc acagtgaaag tgttattttt atcatcgaaa tcagaatgct
    20041 tttatgctgg cagagcgata caagctggtg ctaacggttt tgtcagtaaa tgcaatgatc
    20101 agaatgatat ttttcatgcc gttcagatga tcctctccgg atacacgttt tttcccagcg
    20161 aaacgcttaa ctatataaaa agcaataaat gtagtacgaa tagttcaacg gtcactgtgc
    20221 tatctaatcg tgaagtgacc atattacgtt atctggttag cggattatct aataaagaaa
    20281 ttgccgataa gttattactt agcaataaaa cagttagtgc gcataaatct aatatttatg
    20341 gcaagctagg tttgcattca attgtagagc ttatcgacta cgccaaatta tacgaattaa
    20401 tataatatta attataattg atcataaata tcgcatccgc tttcgccaca cctggccgaa
    20461 caccgctggc taacgctcga taattggcaa aaaagtttag tgtgacattg ccatttgcat
    20521 ctacttcctc agtcgggctc gcctccccca gtgcgagccg ggagcgatcg ctattacgta
    20581 attcgatggc gacggtttgt gccattgcgg gatcatccag agccagcagg ttggtatcgg
    20641 atgccggcgt tcccgtaaat aaaatcgcaa ctgaacccgg aggacatccc tccagccgca
    20701 ggctaaaagg gacgagtgcc gtggtatcgc cagcgttcag tagttgtgtc gtaggccatc
    20761 tgcctaaatc taccgtctta tcaatatccg ctgtgtttac ggtacaggag aaatcaacaa
    20821 cgttaccgtg caaattgata ttaatcgttc ctaaagggtc aactgcccat ccactggaac
    20881 tccacagtag cccgcagaaa cagctaaaga gtactcttct cattctccgt acctcattga
    20941 taatcgacgc gtaaataccc cagcgcgcta aacggccctt cggtcggttt ttgaccggta
    21001 atactgatag gccaggcgcg aagtgtgaca ttggctgccg cagctgcatc cagacggaaa
    21061 ggaataacgc tattgagatc gttaggcgtg atcggcgtat cgttctgatc ggcgacaata
    21121 aaacctaaat cctgattgtc cgacaccatc gcctgaccag aaacggcact ggcttccaga
    21181 cgcattgtta aataagcctg cgcagcaaca ttcgtacatt tgaccgcaat gctcttggtt
    21241 tgcggcatga caccagcagg tcgattaccc ggccctgccg cactaaataa cgatgcgccg
    21301 atatcaccaa aatcaaattc aacaatctgc ccggcattta attcgcagtt ttgcggtact
    21361 tcaacccggc caccaaaact aatggtataa acaggtgtaa ccaacggatc gtaaggcgtt
    21421 gatgtcacat acacggtaaa catcac
//
LOCUS       DAPOAV010000078        21271 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.078, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000078 DAPOAV010000000
VERSION     DAPOAV010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21271
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.078"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            250..750
                     /gene="tssB"
                     /locus_tag="RN951_003304"
     CDS             250..750
                     /gene="tssB"
                     /locus_tag="RN951_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     small subunit"
                     /protein_id="HDX2528260.1"
                     /translation="MSKKFEGSVAPRERINISYVPKTDGQTAEVELPLNMLVVGDTGN
                     TQETSSLDERQAVSVNKHNFGAVMAEAAIGLNFTVPATLKGSTTDDELNVALNIKSLD
                     DFSPDSVARQVPEVNKLLELREALTALKGPMGNLPAFRTQLQALLENEESREQLLKEI
                     GQVSNK"
     gene            785..1009
                     /locus_tag="RN951_003305"
     CDS             785..1009
                     /locus_tag="RN951_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528261.1"
                     /translation="MTAHKNISGTYHLSVADILQVVYQVCFSPSVEINQDGVAALITT
                     LDRRISDLLDEIIHFCEFQQSASHWQRVLH"
     gene            1060..2535
                     /gene="tssC"
                     /locus_tag="RN951_003306"
     CDS             1060..2535
                     /gene="tssC"
                     /locus_tag="RN951_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001501045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     large subunit"
                     /protein_id="HDX2528262.1"
                     /translation="MSLQEEELVSSHAGQPEQASSLLDQIMAQTRIQPGSEGYDVARQ
                     GVTAFIASILQSTASAEPVNKLVVDSMIADIDERISRQMDVIIHAPAFQQVESFWRSL
                     KTMVDRVDFRENIKVNVLHVTKQELLEYFEFAPEIIQSGFYKHVYSSGFGQFGGEPIA
                     AVLGAYEFKNTAPDMKLLQYVSAVGAMAHAPFLSSVSPEFMGLNSWTELPNIKDLYAI
                     FEGPAYTKWRALRDSEDSRYLGLTAPRFLLRQPYSPTDNPVKNFNYYEDVSQNHEDYL
                     WGNTAWMLACNIADSFAKYRWCPNIIGPQSGGAVKDLPVHLFETMGQIQAKIPTEVLV
                     TDRREFELAEEGFITLTMRKDSDNAAFFSANSVQKPKHFPGKDAETNYKLGTQLPYLF
                     IINRLAHYIKVLQREQLGSWKERSDLERELNTWIRQYVADQENPPADVRSRKPLRAAK
                     VEVMDVEGEPGWYQVALSVRPHFKFMGANFELSLVGRLDRE"
     gene            2542..2955
                     /gene="tssE"
                     /locus_tag="RN951_003307"
     CDS             2542..2955
                     /gene="tssE"
                     /locus_tag="RN951_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssE"
                     /protein_id="HDX2528263.1"
                     /translation="MIPDRERTTGSLFERMEASSARNRQGGSIHSLRQSIRQNLRNIL
                     NTRSGSCRGAPELGIDEPEGAENFRESMSRAIEQCIERYEPRISHAEVQVVVSSASSP
                     LDMTFHITAWVTFNETHEVLEFDMAPNGSQHYRVD"
     gene            2959..4809
                     /gene="tssF"
                     /locus_tag="RN951_003308"
     CDS             2959..4809
                     /gene="tssF"
                     /locus_tag="RN951_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssF"
                     /protein_id="HDX2528264.1"
                     /translation="MEFEERYFREELDYLRQLSKLLATEKPHLARFLAEKDADPDIER
                     LLEGVAFLTGNLRQKIEDEFPELTHGLIKMLWPNYLRPVPAMTLIEYTPDMDKSSVPV
                     LIPRNEQFTTNAGEIRVDEVLPSDAKKEEPPPCTFTLCRDIWLLPVRLEQIENRSTTR
                     NGVINITFSVAPGTDFRTLDLNKLRFWLGNDDNYTRDQLYLWFCEYLQGADLTVGEQH
                     LRLPEFMLKAVGFEPQDAMLPWPKNVHSGYRILQEYFCYPDAFLFFDLCGCPALPDGL
                     QAEFFTLQLRFSRPLPVDIRLRRDSLRLYCAPAINLFIHHAEAITLDNRRADYPLVPS
                     RHYPQHYDVFSVNSVVSQVQDMFRKKDLGRPVSTQAARQWPAFESFSHQMEYSRKREV
                     VYWHHRTKTSLFHRGFDHTLAFIHADGSYPSDESLLSNEVVSVSLTCTNRELPSQIRS
                     GDITGTTGKNAAVASFRNITRPTQPLWPVIDGSLHWSLLSAMNLNYLSLLDTDALKQV
                     IANFDRHAIHHPQTARLSQQKLDAIERLETRPVDRLFTGIPVRGLASTLYLHPEPFVC
                     EGEMYLLGTVLSHFLSLYASVNSFHMLTVVNTESQETWKWTERIGQHPLI"
     gene            4773..5855
                     /gene="tssG"
                     /locus_tag="RN951_003309"
     CDS             4773..5855
                     /gene="tssG"
                     /locus_tag="RN951_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssG"
                     /protein_id="HDX2528265.1"
                     /translation="MDGKNRAASSYLSPGNPPADKEQNDPLAQVFHNACSYNFFAMAE
                     LLHRLAKGEKGTPELSLRDDPAQETLRFSADASLAFPCSDISALKRDTSGAFRMTTTF
                     MGLQGSQSPLPGYYLDHLAWKAVHEQSPVGDFLDMFSHRLTQFVWHIWRKYRYHISFR
                     NGGVDAFSQRMYSLVGLGHRQLRDKLAINHSKMLAYSGILANPGRSPEIICGLVSHCF
                     DLSEVTLQNWQRRKVDIEPDQQNSLGSYSLKNGEKLAGRSVLGNFVLGTRVPDLSGKF
                     QLSITSLTRKQFLSFLPSGENFLPLTMFVSFILRDQLAWDLHLGLAPEQVGAMRLGDN
                     KSALLGWTSFLGTPEERPSVTIRVRS"
     gene            5880..7160
                     /gene="tagH"
                     /locus_tag="RN951_003310"
     CDS             5880..7160
                     /gene="tagH"
                     /locus_tag="RN951_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system-associated FHA domain
                     protein TagH"
                     /protein_id="HDX2528266.1"
                     /translation="MPEEKLQTLSLQVINGSELESGRAARCLFTQQGNVGHGPECHWS
                     VQDRQQSIPAQAFTVILHDGTFCLRPQTAQLWLNQAKVTATSDLIQLRQGDEIQIGRL
                     MVRVHLNRGDIPHYDEEMATPETIVTNRDMLTDTLLSTEGAPHYPGMTHRHQLADTVV
                     NGFSADPLQALQSESLITTGDPLSGIAAVRPSAPLSDPASNGGINTPFMDLPPIYASP
                     GDRNDDVSAAEMAQRHLAVTPLLRGLGGSLTMSNSDDADDFLEEAGRTLQAAIKGLLD
                     LQQQRNSLSDKHLRPLEDNPLRLNMDYATALDVMFAEGKSPVHLAAPAAVSESLRNVR
                     HHEEANRAAIVESLRVLLDAFSPQNLLRRFVQYRRSHELRQPLDDAGAWQMYSHYYEE
                     LASDRQQGFEMLFNEVYAQVYDRVLREKQREPEA"
     gene            7157..7681
                     /gene="tssJ"
                     /locus_tag="RN951_003311"
     CDS             7157..7681
                     /gene="tssJ"
                     /locus_tag="RN951_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system lipoprotein TssJ"
                     /protein_id="HDX2528267.1"
                     /translation="MNRKAFLACVLMCVILTGCETAKKISEVIKNPDIQVGSLKEQPS
                     EITVTLLTEPDTNTNAEGESAAVDVQLVYLTDDSKLLAADYDQIASTPLPDVLGKNYI
                     DHQDFNLLPDTIKTLPPVKLDEKTQFIGVVAYFSDDQATEWKQIETVEGTGHHYRLLV
                     HVRQSSIEMKKEDE"
     gene            7684..9015
                     /gene="tssK"
                     /locus_tag="RN951_003312"
     CDS             7684..9015
                     /gene="tssK"
                     /locus_tag="RN951_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssK"
                     /protein_id="HDX2528268.1"
                     /translation="MATTRNKVMWQEGMLMRPHHFQQQQRYNDYLDNQRFRAMNDLSW
                     GFTELTLNNELLAQGKIMIDSASGTLPDGTVFSIPDQDALPDPLHPQNFPDERSRNIY
                     LALPVASDVRNEISDGRRIGRYRLNYADVRDLHSEEGDARTLTLGQLTPRIMSGAEDM
                     SAYITLPLCRISNRHADGSLTLDDDFIPSCQNIQVSKKLRVYLKEVQGAIGGRASDLA
                     NRIGSPAQSGIADVAEFMMLQLLNRNQTRFTHRARRSQLHPEDFYLDLAGLLGELMTF
                     TEPSRLPCPLDVYDHHDLTKTFKTLLPEVKRALHTVLSPRAVNLPLHLRDGIWQADIH
                     DTELLQSATFVLAVAANVPVDQIQRQFIQQSKISSPEKIRNMVSVQIPGIPLRALMVA
                     PRQLPYHSGFSYFELDKSGQAWTEMAAAGAVALHVSGSFPDLNMQLWAIRG"
     gene            9020..9781
                     /gene="icmH"
                     /locus_tag="RN951_003313"
     CDS             9020..9781
                     /gene="icmH"
                     /locus_tag="RN951_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IVB secretion system protein IcmH/DotU"
                     /protein_id="HDX2528269.1"
                     /translation="MDEGSLSLPPFTGHDEKSQRNYHLALRGNSLNPMIDAATPLLGM
                     VMRLSTMNSQTMPEHLFAQVVTDVQAVEQLLQEQGYEPGVIISFRYILCTFIDEAALG
                     NGWSNKNEWIKQSLLVHFHNEAWGGEKVFILLERLIREPKRYQDLLEFLWICFSLGFR
                     GRYKVAAQDQGEFEQIYRRLYHVLHKLRGDAPFPLLHQDKKTQGGRYQLISRLTVKHI
                     FCGGVVVLALFYLFYLLRLDSQTQDILHQLNKLLR"
     gene            9790..12555
                     /gene="tssH"
                     /locus_tag="RN951_003314"
     CDS             9790..12555
                     /gene="tssH"
                     /locus_tag="RN951_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system ATPase TssH"
                     /protein_id="HDX2528270.1"
                     /translation="MIQIDLPPLVKRLNLFSRQALEMAASECMSQQAAEITVSHVLIQ
                     MLAMPRSDLRVITRQGDIGMEELRQALTVENYTTARSADSYPAFSPMLVEWLKEGWLL
                     ASAEMQHSELRGGVLLLALLHSPLRYIPPAAARLLTGINRDRLQQDFVQWTQESAESV
                     VPDADGKGAGTMTDASDTLLARYAKNMTADARNGRLDPVLCRDHEIDLMIDILCRRRK
                     NNPVVVGEAGVGKSALIEGLALRIVAGQVPDKLKNTDIMTLDLGALQAGASVKGEFEK
                     RFKGLMAEVISSPVPVILFIDEAHTLIGAGNQQGGLDISNLLKPALARGELKTIAATT
                     WSEYKKYFEKDAALSRRFQLVKVSEPNAAEATIILRGLSAVYEQSHGVLIDDDALQAA
                     ATLSERYLSGRQLPDKAIDVLDTACARVAINLSSPPKQISALTTLSHQQEAEIRQLER
                     ELRIGLRTDTSRMTEVLVQYDETLTALDELEAAWHQQQTLVREIIALRQQLLGVAEDD
                     AAPLPDADTVEDTQPESESEQDNTGAVPADEADREQPEETAETVSPVQRLAQLTAELD
                     ALHNDRLLVSPHVDKKQIAAVIAEWTGVPLNRLSQNEMSVITDLTKWLGDTIKGQDLA
                     IASLHKHLLTARADLRRPGRPLGAFLLAGPSGVGKTETVLQLAELLYGGRQYLTTINM
                     SEFQEKHTVSRLIGSPPGYVGYGEGGVLTEAIRQKPYSVVLLDEVEKAHPDVLNLFYQ
                     AFDKGEMADGEGRLIDCKNIVFFLTSNLVYQVIVEHADDPETMQEVLYPVLADFFKPA
                     LLARMEVVPYLPLSKETLATIIAGKLARLDNVLRSRFGAEVVIEPEVTDEIMSRVTRA
                     ENGARMLESVIDGDMLPPLSLLLLQKMAANTAIARIRLSAVDGAFTADVEDAQNDESV
                     TKDETVL"
     gene            12552..13295
                     /gene="tagO"
                     /locus_tag="RN951_003315"
     CDS             12552..13295
                     /gene="tagO"
                     /locus_tag="RN951_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system-associated protein
                     TagO"
                     /protein_id="HDX2528271.1"
                     /translation="MSRLRVFRQTGWFIAGLMTGLPATAAPAEASSMAGVAVAVATTT
                     PPDATATLQAIQSCRRESAALERLDCYDRLLAPLSPSGFDGALVKAGFVGEAWTRATE
                     QEKRREGNTTELLVTQVPGERPTVVITTPAIGHVPPRPVLMFSCVDNITRMQVALMHP
                     LDVHDIAVTLNADNRALRSHWFVRENGTLLESSRGLSGIDEIKQLFGAKTLTVDTGAD
                     NAAGKLTFNIDGLARAIAPLRDACHWAGE"
     gene            13300..14712
                     /gene="tssA"
                     /locus_tag="RN951_003316"
     CDS             13300..14712
                     /gene="tssA"
                     /locus_tag="RN951_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein TssA"
                     /protein_id="HDX2528272.1"
                     /translation="MAMDLRDPNVWISHLLENLPEEKLASALKDDNPNWEYIDGEIVK
                     LGSLAHSQLDIPELQRRGLVILASESKDFRLLAHLLRTLQHAGDPHLALRLLALYVEH
                     YWAVAAPQNMAHKKRFASQVIKRFETGIEGFSQNAATEQRDALSGELAKLAQCWQSHN
                     APELAQATDDLFALYQRAFNRAAPAPVPTPAASGSSPQTTATSESGVTQPSAPAPQIV
                     IDSHDDKAWRDTLLKVAAILCERQPDSPQGYRLRRHALWQNITSTPQAESDGRTPLAA
                     VSADMVADYHAQLGSADMALWQQVEKSVLLAPYWLDGHCLSAQTALRLGYKQVADAIR
                     DEVIRFLERLPQLTGLLFNDHTPFISEQTKQWLAASPDAKVAPVAQIGEESKAARACF
                     AEQGLEAALRYLDMLPEGDPRDQFHRQYLAAQLTEEAGLVQLAQQQYRMLFRMGLQMM
                     VADWEPSLLEQLEQKFTAEQ"
     gene            14821..18255
                     /gene="tssM"
                     /locus_tag="RN951_003317"
                     /pseudo
     CDS             14821..18255
                     /gene="tssM"
                     /locus_tag="RN951_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308245.2"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system membrane subunit TssM"
     gene            18266..19618
                     /locus_tag="RN951_003318"
     CDS             18266..19618
                     /locus_tag="RN951_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001087757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system ImpA family N-terminal
                     domain-containing protein"
                     /protein_id="HDX2528273.1"
                     /translation="MNSNVLTQTIVTGSDPRGLPEFSAIREEINKASHPSQPELNWKL
                     VESLALAIFKANGVDLHTATYYTLARTRTQGLAGFCEGAELLAAMVSHDWDKFWPQGG
                     PARTEMLDWFNSRTGNILRQQISFAESDLPLIYRTERALQLICDKLQQVELKRVPRVE
                     NLLYFMQNTRKRLEPQLKSNTENAAQTTVRTLIYAPETQASSTPEAVVPPLPGLPEMK
                     VEVRSLTENPPQASVIKQGSTVRGFIAGIACSVAVASALWWWQVYPVQQQLLQVNDTV
                     QGAATVWMASPELENYERRLQQLLDTSPVQPLETGMQMMRVADSRWPESLQQQQASTQ
                     WNEALKTRAQSSPQLRGWLQTRQDLHAFADLVMQREKEGLTLSYIKNVIWQAERGLGQ
                     ETPVESLLTQYHDARAQKQNTDALEKQINERLEGVLSRWLLLKNNVMPEAATGTTAEK
                     "
     gene            19642..20124
                     /locus_tag="RN951_003319"
     CDS             19642..20124
                     /locus_tag="RN951_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hcp family type VI secretion system effector"
                     /protein_id="HDX2528274.1"
                     /translation="MANISYLSLSGETQGLISAGCSTLDSVGNKAQPEHKDQIMVYAL
                     MHSISRSQNVNHHELIITKPVDKSSPLLAKALSDNEKMAICEFILYRTSKAGIYQPYY
                     KINLSKARISSIDFVTPHAVLEKELEPQERIAFIYEDISWEHTLAGTNAMSKWQDRVQ
                     "
     gene            20168..21082
                     /locus_tag="RN951_003320"
     CDS             20168..21082
                     /locus_tag="RN951_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528275.1"
                     /translation="MAGLRNNNNTQNAQWADYVGDILRGAQPINQLVPQHPYLNDVPF
                     IDELRHQNTHHVIPLTLDVAKKILSPITSFDYIHFITTHPSGIKDTLAWLVNAGKLMT
                     EFDDNGKIIFNLNALKYTKASYFEILGEKYIKITTSSPWLLEKLGKYIFSSRAPQVLE
                     LAIGWRGALSESIKGVKFCIWFSVAWRTIEFIMSSERDLVNFLGDFSMDVAKAVIAGG
                     VATAIGSLASFACVSFGFPVILVGGAILLTGIVCTVVLNEIDVQCHLSEKLKYAIRDG
                     LKRQQELDKWKRENMTPFMYVLNTPPVI"
     gene            21092..>21271
                     /locus_tag="RN951_003321"
     CDS             21092..>21271
                     /locus_tag="RN951_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528276.1"
                     /translation="MRLHVKLKEFLSMFFMAILFFPAFNASLFFTGVKPLYSIIKCST
                     EIFYDWRMLILCFGFM"
BASE COUNT         5096 a         5702 c         5794 g         4679 t
ORIGIN      
        1 taaattattg ccataataca cctgacgcga attgcacagg ttcatacaat ctatttaacg
       61 cttgcagaat acccctcttt acgatcgata aaaagtcctt ttcttattta ttttgaagcg
      121 taaaatgcgg ggtgatgaag gagtggtgat tttattttca ccgctatcaa ggcggcattt
      181 ccgatatttt ttacggtacg aatatgccgt gttcatggcc tgtacgagat aacatgacgg
      241 atcactttta tgagcaaaaa atttgaaggc agcgtcgcgc ctcgcgaacg tattaatata
      301 tcgtatgtcc caaaaacaga tggccagacg gctgaagtgg aacttccgct taacatgctc
      361 gttgtcggcg ataccggaaa tacgcaggaa acatcctcac tggatgaacg tcaggcagtt
      421 tccgttaaca agcacaattt cggtgcagtg atggctgaag cagccattgg cctcaatttt
      481 accgtccccg ccacgctgaa gggaagcaca acggacgatg agctgaatgt ggcgctgaat
      541 atcaagtcac tggatgattt ttcaccagat agcgtggccc ggcaggttcc ggaagtgaat
      601 aaattgctgg aactgcgtga agcactgact gcactgaagg ggccgatggg taaccttccg
      661 gcattccgta cccagctcca ggcattgctg gaaaatgaag agtcccgcga gcagttgctc
      721 aaagaaatcg gccaggtgag caataaataa ccaccactat ttcattaaac agggttatcc
      781 aggcatgacg gcacacaaaa atatctccgg gacataccac ctctctgttg cagacattct
      841 gcaggtggtt taccaggtat gtttcagccc gtccgttgaa atcaaccagg atggtgtggc
      901 tgcgctgatt acaacactgg atcgccgtat cagtgatcta ttggatgaga ttatccattt
      961 ttgtgagttt cagcagagcg cgtcgcactg gcagcgcgta cttcactgat ggcgaaaagc
     1021 cggtttcaga aacacagcta aaacagaagg attttcagta tgtctttaca ggaagaggaa
     1081 ctcgtttcca gtcatgccgg gcagcctgag caggcatcgt cgctgcttga tcaaatcatg
     1141 gcacagaccc gtattcagcc cggttcggaa ggttatgacg ttgcccgcca gggtgtgaca
     1201 gcctttattg ccagcatcct gcaatccact gcatctgccg aaccggtcaa taaactggtc
     1261 gtggacagca tgattgcaga tattgatgaa cgcatcagcc gccagatgga tgtcatcatc
     1321 catgcgcctg cctttcagca ggtcgagtcg ttctggcgct cactgaaaac catggtggat
     1381 cgcgttgatt tccgtgaaaa catcaaggtc aacgtgcttc atgtcaccaa gcaggaactt
     1441 ctggaatact ttgagtttgc gccagaaatt attcagtccg gattttataa gcacgtttat
     1501 tcgtccggtt tcggacagtt tggcggtgaa cccatcgctg ccgtgctggg cgcttatgag
     1561 ttcaaaaata ccgcgcctga catgaaactg ctgcaatacg tcagtgcagt gggcgcaatg
     1621 gcgcacgcac cgttcctgtc ctccgtttcc ccggagttta tggggctgaa ctcgtggacc
     1681 gaactgccta atatcaaaga tctttatgcc atctttgaag gtccggccta caccaaatgg
     1741 cgcgccctgc gtgactcgga agattcgcgc tatttagggc ttacggcacc ccgcttcctg
     1801 cttcgccagc cctattcacc aacagataac cctgttaaga actttaacta ttacgaagat
     1861 gtcagccaga accacgaaga ttatctgtgg ggtaatacgg cctggatgct ggcatgcaat
     1921 atcgcagaca gttttgccaa ataccgctgg tgtccaaaca ttatcggtcc gcaaagcggc
     1981 ggcgcagtga aagatctgcc ggtgcatctg ttcgaaacga tggggcagat tcaggccaaa
     2041 atcccaaccg aggtgctggt caccgatcgc cgcgaatttg aactggctga agagggtttt
     2101 atcaccctta ccatgcgtaa agactctgat aatgcagcct ttttctctgc aaactcggta
     2161 caaaaaccga agcactttcc gggaaaagat gcagaaacca actataagct gggtacgcag
     2221 cttccttatc tcttcatcat caatcggtta gcgcactaca tcaaggtgtt gcagcgtgaa
     2281 caactggggt catggaaaga aaggagcgac ttagaaagag agcttaatac ctggatccgt
     2341 cagtatgttg ccgaccagga aaacccgcct gcagacgtgc gcagccgcaa acctctgcgc
     2401 gctgccaaag ttgaggttat ggatgtagaa ggcgaacccg gctggtacca ggttgcgcta
     2461 agcgtgagac ctcattttaa atttatgggg gcaaattttg agctttccct ggttggccgg
     2521 ttagacaggg agtaacacac catgataccg gatcgggaaa gaaccacagg ttctcttttt
     2581 gagcgtatgg aagcctcttc ggccagaaac cggcagggag gcagtattca ttcgctcagg
     2641 caatccattc gccagaacct acgaaacatt cttaataccc ggtccggtag ttgccggggt
     2701 gcgcctgagc tgggcattga tgaaccggaa ggggctgaaa acttccgcga atccatgagt
     2761 cgggccatcg agcaatgtat agaacgctat gaaccccgga tctcacacgc tgaagtgcag
     2821 gtagtggttt catccgcctc cagcccgctg gatatgacgt ttcatattac agcctgggtg
     2881 acatttaacg aaacgcatga ggtgcttgaa tttgatatgg caccgaatgg cagccagcat
     2941 taccgggtgg actgacaaat ggaatttgaa gaacgctatt tccgggaaga actcgattac
     3001 ctgcgccagc ttagcaagct gctggcaacg gaaaaacccc atctggcccg cttcctggcc
     3061 gaaaaagatg cggatccgga tattgaacgc ctgctggaag gggtggcttt tcttaccggc
     3121 aatctccgcc agaaaattga ggatgaattc ccagaactga cgcacgggct tattaagatg
     3181 ctatggccta attacctgcg tccggttccg gcaatgaccc ttattgaata tacgccggat
     3241 atggataagt cttctgtacc ggtgttaatc ccccgtaatg agcagtttac aaccaacgcc
     3301 ggggaaatca gagttgatga agtgctgccc tctgatgcta aaaaggagga gccgcctccc
     3361 tgtaccttca ccctctgccg ggatatctgg ctgctgcccg ttcgcctgga gcagattgaa
     3421 aaccgcagta cgacccgtaa tggtgttatc aacatcacct tttcggtcgc accgggaacg
     3481 gacttccgca cgctggatct gaacaaactt cgcttctggc tcggcaatga cgacaactat
     3541 acccgtgacc agctttattt atggttctgc gaatacttgc agggtgccga cctgactgtg
     3601 ggtgaacagc atcttcgcct gcctgagttt atgctaaaag ctgtcggttt tgagccgcag
     3661 gatgccatgc tgccctggcc gaaaaacgtc cacagcggct accggatcct tcaggagtat
     3721 ttctgttacc ccgatgcgtt tctctttttt gatctttgtg gttgtccggc tttgcctgac
     3781 ggattgcagg cggaattctt taccctgcaa ctgcgttttt cgcgcccttt gcccgtggac
     3841 atccggctgc gccgcgattc cctgcgcctg tattgcgcac ctgccattaa tttatttatc
     3901 caccatgcag aagccatcac gctggacaac cggcgggcag actatccgct ggttcccagc
     3961 cgccattacc cacaacatta cgatgtattt tccgttaaca gtgtggtgag ccaggtccag
     4021 gatatgttca ggaaaaaaga tctggggcgt cctgtttcga cgcaggccgc gcgccagtgg
     4081 ccagcctttg aaagtttcag ccatcagatg gaatacagcc ggaagcggga agtggtgtac
     4141 tggcatcacc ggaccaaaac atccctgttc catcgcggct ttgatcatac ccttgccttt
     4201 atacatgctg atggcagtta tccgtcagac gaatctctgc tcagtaatga agtggtttcg
     4261 gtatcgctga cctgtaccaa ccgtgagctt ccgtcacaaa ttcgttccgg cgatatcacc
     4321 ggcacaaccg gtaaaaatgc agctgttgct tcatttcgca acattacccg cccgacgcaa
     4381 ccactctggc cggtcattga tggcagcctg cactggtccc tactctccgc catgaacctg
     4441 aattatctgt cattactgga tacggacgcg ctgaagcagg tcatcgccaa ctttgatcgc
     4501 cacgcaatcc atcatccgca gacggcacgg ctgtcacaac aaaagctgga tgccattgag
     4561 cgtctggaga cccgccccgt tgatcgcctg tttacgggta ttcccgtccg gggactggcc
     4621 tccacgctgt atctgcaccc ggagccgttt gtctgtgaag gggaaatgta tctgctcggt
     4681 acggtgcttt cgcattttct gtcgctgtac gccagcgtta actcattcca catgctgacc
     4741 gttgtgaaca cagaaagcca ggagacatgg aaatggacgg aaagaatcgg gcagcatcct
     4801 cttatctgag tccgggaaat cccccggcag ataaagagca gaatgatccg ctggcacagg
     4861 ttttccataa tgcctgctct tacaattttt ttgcgatggc ggagctgttg caccgcctgg
     4921 caaagggtga aaaggggacg ccagaattat ccctgcgtga cgatccggca caggaaaccc
     4981 tgcgtttcag cgccgatgcc agccttgcct tcccgtgcag tgatatcagt gcgctgaaac
     5041 gggatacatc aggggcattc aggatgacca ccacctttat ggggttacag gggagccagt
     5101 cgcctctccc cggttattac ctcgatcacc tggcctggaa agcggtacat gaacaaagtc
     5161 cggtaggtga ttttctggat atgttcagcc accgcctgac ccagtttgtc tggcatatct
     5221 ggcgtaagta ccgctatcac atcagttttc gtaacggcgg tgtggatgcg ttctcgcagc
     5281 gcatgtactc ccttgtcggg ctgggccacc gccagcttcg cgataagctg gcgattaatc
     5341 acagcaaaat gctggcgtat tccgggatcc tggcaaatcc gggacgatcc ccggaaataa
     5401 tctgtggcct ggtgtcccac tgctttgatt tgtcagaagt gacgctgcaa aactggcaac
     5461 gtcgcaaggt ggatattgaa ccggatcagc aaaatagtct ggggagctat tctcttaaaa
     5521 atggcgaaaa actggcggga agatcggtac tgggcaactt tgttctgggt acacgagtgc
     5581 ccgatctcag cggaaaattc cagctcagta ttaccagcct gacccgaaaa cagttcctct
     5641 cttttctgcc gtccggcgaa aacttcctgc cactgacgat gttcgtgtcc ttcatcctgc
     5701 gcgatcagct tgcctgggac ttacatctgg ggctggcgcc ggagcaggtg ggcgcaatgc
     5761 gcctgggtga taacaaaagt gcgctgctgg gctggaccag cttcctcggc acaccggaag
     5821 aacgaccctc agtcaccatc agggtacggt cgtaaattat gataatcacg gagcagaata
     5881 tgccggaaga gaaactacag acgctttcat tgcaggtcat taacggcagt gagctggaaa
     5941 gcgggcgggc ggcgcgctgt ctattcacac agcagggaaa tgtcggccat ggccccgaat
     6001 gccactggtc ggtacaggat cgtcagcaga gcattccggc ccaggctttt accgttatcc
     6061 tgcacgatgg cacattttgt ctgcgcccgc agacggcaca actgtggctg aatcaggcaa
     6121 aagtcacagc aacatcagac ctaatacagt tgcgccaggg cgatgagatc cagatcggac
     6181 ggctgatggt gagggttcat ctgaaccggg gagatattcc ccattacgat gaggaaatgg
     6241 ccactcccga aaccatcgtt accaatcgcg atatgctcac ggataccctg ctatcaacgg
     6301 agggtgcgcc acactatccg ggaatgactc accggcacca gcttgcagac accgtggtaa
     6361 acggtttttc tgccgatcca ctccaggcac ttcagtccga aagcctgatt accacgggcg
     6421 atccgctttc aggcattgcg gctgtccggc catcggcacc gctgtccgat ccggcaagta
     6481 atggggggat caatactccg tttatggatc tgccgcccat ttatgccagc cccggcgatc
     6541 gtaatgacga cgtctctgcg gcagaaatgg cgcaacgcca ccttgcggtc acccccttac
     6601 tgcgcggtct tggcggctcg cttaccatga gcaattccga cgatgcggat gattttctgg
     6661 aggaggccgg acgaacgtta caggccgcaa taaaaggtct gctcgatttg cagcagcagc
     6721 gtaacagcct ctcagacaaa catttgcgcc cgctggaaga taacccgctg cgcctgaaca
     6781 tggattacgc caccgcgctc gacgtaatgt ttgccgaagg taaaagcccg gtacatctgg
     6841 cggctcccgc cgccgtcagt gaaagcctgc gcaatgtccg ccaccacgaa gaagctaacc
     6901 gggcagcgat tgtggagtcg cttcgtgtcc tgctggatgc tttctcacca caaaatctgc
     6961 tgcgccgctt tgtgcagtac cgccgcagcc atgaactgcg ccagccgctg gatgatgccg
     7021 gagcatggca aatgtacagc cattattacg aagaactggc ctccgatcgc cagcaggggt
     7081 ttgagatgct gtttaacgag gtctacgccc aggtctatga ccgggtgctt cgtgaaaaac
     7141 agcgggagcc ggaagcatga acaggaaggc gtttctggcc tgcgtgctga tgtgcgtcat
     7201 attaaccggc tgcgaaacgg cgaaaaaaat cagcgaggtg atcaaaaacc cggatatcca
     7261 ggtcgggagc ctgaaggagc aaccttcgga aataaccgtc accctgctga ctgaaccgga
     7321 caccaatacc aatgcggagg gtgaatcagc cgccgtggat gtgcaactgg tgtacctgac
     7381 tgacgactca aaattgctgg cagccgacta tgaccagata gccagtacgc cgctaccgga
     7441 tgtgttgggt aaaaactata tcgaccacca ggatttcaac ctgttgccgg acaccatcaa
     7501 aaccctgccg ccggtaaagc tggatgagaa aacgcagttt attggtgtcg tggcctattt
     7561 ctccgatgac caggccactg aatggaaaca aatcgagacg gtggaaggaa ccggccacca
     7621 ttaccgcctg ctggtgcatg tacgtcaaag cagcatcgaa atgaaaaaag aggatgaata
     7681 attatggcaa ccacccgcaa caaggtgatg tggcaggaag ggatgctgat gcgcccacac
     7741 catttccagc aacagcagcg ttacaacgac tacctggata accagcgttt ccgggccatg
     7801 aatgatttat cctggggatt taccgaactc accctcaaca atgaactgct ggcgcagggt
     7861 aagatcatga ttgacagcgc gtcaggcaca ctgcccgacg gcaccgtctt ttctatcccc
     7921 gaccaggacg cactgcccga tccgctgcac ccgcaaaatt ttccggacga aagaagccgc
     7981 aatatctacc tcgctctgcc ggtcgccagt gatgtgagaa atgaaatcag cgacggacgg
     8041 cgaatcgggc gttaccggct gaattatgcc gatgtccggg atttgcattc agaagaaggt
     8101 gacgcgcgaa cattgacgct gggtcaactg acgccgcgca ttatgagcgg tgcagaagat
     8161 atgagcgcct atattacgct cccgctttgc cgtatcagca atcgccatgc cgatggctcc
     8221 ctgacgttgg atgacgattt tatcccctcc tgccagaata ttcaggtcag taagaaactg
     8281 cgtgtttatc tcaaagaggt acagggggcc attggcggac gggcaagcga tctggcaaac
     8341 cgtattggct ctccggcgca gagcggcatc gcggatgtgg cggaatttat gatgttgcag
     8401 ttacttaacc gtaaccagac ccggtttacc catcgcgccc gccgatccca gctccacccg
     8461 gaagatttct accttgatct tgctgggttg ctgggtgaac tgatgacctt taccgagccg
     8521 tcgcgcctgc cctgcccgct tgatgtgtat gatcatcatg atctgaccaa aacatttaaa
     8581 acactgttac cggaagtcaa acgggcgctg cataccgtac tgtcgccaag agcggtcaat
     8641 ctgccgctgc atctgcgtga cggtatctgg caggccgata tccatgacac agaactgctg
     8701 caatctgcca cctttgtgct ggccgtggcg gcaaacgtgc cggtcgatca gatccagcgt
     8761 cagtttatcc agcagtcgaa aatttcctcg ccggaaaaaa tccgcaatat ggtcagtgtg
     8821 cagatccccg gtattccatt gcgtgccctt atggtggctc cccgccagct tccttaccat
     8881 tccgggttca gctatttcga actcgacaag agtggccagg cctggacaga aatggctgcc
     8941 gccggggccg ttgcactgca tgtttccggc agtttcccgg atctgaacat gcaactgtgg
     9001 gcgataagag ggtaagacga tggatgaggg gtcactgtct ctgccaccat ttaccggaca
     9061 cgacgaaaaa agccagcgca actaccatct cgcgcttcgt ggcaacagcc tgaatccgat
     9121 gatcgacgcg gccacgccgc tactcggtat ggtaatgcgc ctttcaacca tgaacagcca
     9181 gacgatgccg gagcatcttt ttgctcaggt ggtgacagat gttcaggccg tggagcaatt
     9241 gcttcaggag cagggctacg aaccgggcgt gattatctcg tttcgctaca tcctctgcac
     9301 gtttattgat gaagcggcgc tcggtaacgg ctggtcaaac aagaacgagt ggatcaagca
     9361 gtcattgctg gtccatttcc acaacgaagc ctggggtggc gagaaagttt tcatcctgct
     9421 ggagcgcctg atccgtgaac ccaaacgtta ccaggatctg ctggaatttc tctggatctg
     9481 tttttctctg ggatttcgcg ggcgctacaa agtggcagca caggatcagg gggaatttga
     9541 gcagatctac cgccgtctgt accacgttct gcataaactg cgcggcgatg cccctttccc
     9601 gctgttacac caggacaaaa aaacccaggg cgggcgttat cagctcatca gtcgcctgac
     9661 tgttaaacat attttttgtg gtggcgttgt cgtgctggcg ttgttttacc tgttctatct
     9721 gttgcggctg gacagccaga cgcaggacat cctgcaccag ctaaacaaat tacttcgata
     9781 aggacgttta tgatccagat tgatcttccc ccgctggtaa aacggctgaa cctgttctcc
     9841 cgccaggcgc tggagatggc cgcctctgaa tgtatgagtc agcaggcagc ggaaattacc
     9901 gtcagccatg tgctcattca gatgctcgcc atgccacgca gtgacctgcg ggttattacc
     9961 cgccagggcg atattggcat ggaagagttg cgccaggcgc tgacggtaga gaactacaca
    10021 accgcccgtt ctgcggacag ctacccggcg ttttccccga tgctggttga gtggcttaaa
    10081 gagggctggc tgctggcgtc ggctgagatg cagcacagcg aactgcgcgg cggcgtgttg
    10141 ctgctggccc tgctgcattc gccgctgcgt tatataccgc ctgctgccgc ccggctgttg
    10201 accggcatta accgtgaccg tctgcaacag gactttgtgc agtggacaca ggagtcggcg
    10261 gaatcagtcg tgccggatgc agacggtaaa ggcgcaggca caatgacgga cgcctctgac
    10321 accctgcttg cccgctatgc caaaaacatg accgcagacg cccgtaacgg caggcttgac
    10381 ccggtactgt gccgcgacca cgaaatcgac ctgatgatcg acattctctg ccgccgccgt
    10441 aaaaacaacc cggtggtggt gggcgaagcg ggcgtgggca aaagcgcact gattgaaggg
    10501 ctggcgctgc gcatcgtggc aggccaggtg ccggacaagc tgaaaaacac cgatatcatg
    10561 acccttgact tgggcgcatt gcaggccggg gcgtcggtga agggtgaatt cgaaaaacgt
    10621 ttcaaagggc tgatggcgga ggtcatttcc tccccggtgc cggtcattct gtttatcgac
    10681 gaagcacata ccctgattgg cgcgggcaac cagcagggcg ggctggatat ctccaacctg
    10741 ctcaaaccgg cgctggcgcg cggcgagctg aaaaccatcg ccgccaccac ctggagcgag
    10801 tacaaaaaat acttcgaaaa agatgccgcc ctgtcgcgcc gcttccagtt ggtgaaggtc
    10861 agcgaaccca acgctgccga agccaccatt attctgcgcg gtctgtcggc ggtctatgaa
    10921 cagtctcacg gcgtgctgat tgatgatgac gccttgcagg ccgctgcgac attaagcgag
    10981 cgttatctct ccgggcgtca gttaccggac aaagcgattg atgtgctgga taccgcctgc
    11041 gcccgtgtgg ccatcaacct gtcgtcgccg ccgaagcaaa tctcggcgct gaccactctg
    11101 agccaccagc aggaggcgga aattcgccag cttgagcgcg agcttcgcat cggactgcgt
    11161 accgacacat cacggatgac agaggtgctg gtgcagtatg atgaaacgct gacggcgctg
    11221 gatgaactgg aagcggcctg gcaccagcag cagacgctgg tccgggagat tatcgcgctg
    11281 cgccagcagt tactgggcgt ggcagaggac gatgcggcgc cgttgccgga cgcagatacc
    11341 gtggaggata cgcagccaga gtcagagtca gaacaggata ataccggtgc cgtaccggct
    11401 gatgaggccg acagagaaca accggaagag accgctgaaa cagtttcccc ggtacagcgg
    11461 ctggcccagc tcactgccga actggacgcc ctgcataacg accggttgct ggtctccccg
    11521 cacgtcgata aaaaacagat tgcggcggtg attgccgaat ggaccggcgt gccgctcaac
    11581 cgcctgtcgc agaatgaaat gtcggtcatc accgacctga cgaaatggct gggtgacacc
    11641 atcaaaggcc aggacctggc gattgccagc ctgcataagc atctactgac cgcacgcgcc
    11701 gacctgcgtc gtccgggacg cccgctcggt gcgttcctgc tggctggccc cagcggtgtg
    11761 ggtaaaaccg aaaccgtcct gcaactggca gagctgctct acggcggtcg ccagtacctg
    11821 accaccatca atatgtccga attccaggag aaacacaccg tctcgcggct gattggttcg
    11881 cctccgggct acgttggcta cggtgaaggc ggcgtactga ccgaagcgat tcgtcagaaa
    11941 ccctactcgg tagtactgct cgatgaagtg gaaaaagcgc acccggatgt gctcaacctg
    12001 ttctaccagg cgttcgataa gggcgaaatg gcagacggtg aaggccgcct gattgactgc
    12061 aaaaatatcg tcttcttcct gacgtccaac ctcgtctacc aggtaatagt cgagcatgcc
    12121 gatgacccgg aaaccatgca ggaagtactg tatccggtgc tggccgactt cttcaaacct
    12181 gccctgctgg cgcgtatgga agtggtgccg tatctgccgc tgtcgaaaga gacgctcgcc
    12241 accattatcg ccggaaaact ggcccgtctg gataacgtgc tgcgcagtcg ctttggtgca
    12301 gaagtggtca ttgaaccaga agtgacggac gaaatcatga gccgcgtcac ccgcgcggaa
    12361 aacggcgcga ggatgctgga atcggtcatc gatggcgaca tgctaccgcc gctctcgctg
    12421 ctgctgttgc agaaaatggc ggctaacacg gcgattgccc ggattcggtt gtcggcagtg
    12481 gacggcgcat ttacggcaga cgtggaagat gctcagaacg acgagtccgt cacaaaggat
    12541 gaaacggttt tatgagcagg ttgcgcgttt tccggcagac aggatggttt atcgcgggcc
    12601 tgatgacggg cttacccgcc actgccgcgc ccgcagaagc atcgtcaatg gccggtgtgg
    12661 cggtcgccgt cgccaccacg accccgccgg atgcgacagc cacgttacag gccatacagt
    12721 cctgtcggcg ggagtccgcg gcgctggagc ggcttgactg ctatgaccgc ctgctggcac
    12781 cgctgtcccc gtcagggttt gacggggcgc tggtcaaagc cggttttgtg ggcgaggcct
    12841 ggacccgcgc cacagagcag gaaaaacgcc gcgagggcaa caccacagaa ctgctggtga
    12901 cgcaggtgcc gggggagcgc ccgacggtgg tgataaccac cccggctatc ggtcatgttc
    12961 cgccacgccc ggtgctgatg ttcagttgcg tggacaatat cacccggatg caggtggcgc
    13021 tgatgcaccc tctggatgtc catgatatcg ccgtcactct gaatgccgac aaccgggcat
    13081 tgcgcagcca ctggtttgtg cgcgagaacg gcaccctgct ggagtccagc cgggggttat
    13141 ccgggattga tgaaattaag caactgttcg gcgcaaaaac gctgacggtg gataccggcg
    13201 cagacaatgc cgccggaaag ctgaccttta acattgacgg gctggcaagg gcgattgctc
    13261 ccctgcgcga tgcctgccac tgggcgggag aataaaaata tggcaatgga cttacgcgat
    13321 ccgaatgtct ggatatcgca cctgctggaa aacctgccgg aagagaaact ggcatcggcg
    13381 ctgaaagatg acaacccgaa ctgggagtat atcgacggcg aaatcgtcaa gctgggatcg
    13441 ctggcccaca gtcaactgga tatcccagaa ctccagcgcc gggggctggt cattctggct
    13501 tcggagagta aggattttcg tctgctggcg catctgctga gaaccctgca acacgccggt
    13561 gatcctcatc tcgcattgcg cctgctggcg ctgtatgtgg agcattactg ggcggtggct
    13621 gcgccgcaga atatggcgca taaaaaacgc tttgccagcc aggtcattaa acgctttgaa
    13681 acaggtattg aaggtttttc acagaacgcc gccacagagc agcgcgatgc gctgtcaggg
    13741 gaactggcaa aactggcgca atgctggcag tcacataacg ccccggaact ggcacaggct
    13801 actgatgatc tttttgccct gtaccagcgt gcgtttaatc gtgcggcacc ggctcctgtc
    13861 cccactccgg cggcctccgg tagttcacca cagaccaccg ccacgtctga aagcggcgtg
    13921 acgcaaccca gtgctccggc tccccaaatc gtcatcgaca gtcatgacga caaagcctgg
    13981 cgcgacacgc tgttaaaagt ggcggccatt ttatgtgaac gccagccgga ttcaccgcag
    14041 ggctaccgtc tgcgccgcca tgcgctttgg cagaacatca ccagtacgcc ccaggcggaa
    14101 agcgatggcc gtactccact ggctgcggtc tccgccgata tggtggcaga ttaccatgct
    14161 cagctcggta gtgccgatat ggcgctgtgg cagcaggtgg agaaaagcgt actgctggct
    14221 ccttactggc tggatggtca ctgcctttct gcacagacgg cgctgcgtct gggttacaaa
    14281 caggtggcag acgccatccg cgatgaggtc atccgcttcc ttgagcgtct gccccagctt
    14341 accgggttgc tgtttaatga ccacacaccg tttatcagtg agcagacgaa acaatggctg
    14401 gcagcttcgc ccgacgccaa agttgcaccg gttgcgcaaa tcggtgagga atcgaaggca
    14461 gccagagcct gttttgctga gcagggtctg gaggcggcgc tgcgatatct ggacatgcta
    14521 cccgaaggcg atccccgcga tcagtttcac cgccagtacc ttgccgcaca gttgacggaa
    14581 gaggcggggc tggtacagct tgcgcagcag cagtaccgga tgttgttcag gatgggattg
    14641 cagatgatgg tggcagactg ggagccgtcc ctgcttgagc agctagaaca aaaattcacg
    14701 gcagaacaat aaaagagaac aggagttttt gtgttcagat taccaacacc ccgactactc
    14761 agcggactca aatcagccct gcgaccggcg atgccccggt ttaaagtctc tgctttctgg
    14821 ctgctgatac tggcgtggat ttttctgctg gtgtggatct ggtggaaagg cccgacgtgg
    14881 acgctgtatg aagaacagtg gctcaaacca ctggcgaacc gctggctggc aacggcggcg
    14941 tgggggatta ttgccctgat gtggcttacc gtccgggtga tgaagcgcct gcaacagctt
    15001 gaaaaaatgc aaaagcaaca gcgcgaggaa gccgttgatc cgctcagcgt ggaactgaac
    15061 gcccagcagc gttatcttga ccgctggctg ctgcgcctgc aacgctatct cgacaaccgc
    15121 cgtttcctgt ggcagttgcc gtggtatatg gtcatcggcc cggcgggcag tggcaaaacg
    15181 acactgctgc gcgaggggtt tccgtccgac attatttatg ccccggaggg cgcgcgcggc
    15241 gcagaacaac gcctgtacct tacgccccat gtcggtaaac aggcggtgat ctttgatatc
    15301 gacggcacac tctgcgctcc cgctgatgcg gatatcctgc atcgccgtct gtgggaacat
    15361 gccctcggct ggctgaaaga aaagcgcgcg cgccagccgc tgaacgggat tattctgaca
    15421 ctcgatttac ccgatctgct taccgcagac aaacgccgcc gcgagcatct gttacagacg
    15481 ctgcgcagcc gcttgcagga tatacgccag catcttcact gccagttacc ggtttacgtg
    15541 gtactcaccc ggcttgattt attgcagggt tttgccgccc tgttccagtc actgaacaga
    15601 caggatcgcg atgcgattct gggcgtcacg ttcacccgcc gcgcccatga aaatgatgac
    15661 tggcgaacag agttgaatgc tttctggcag acatgggtgg atcgaatgaa tctggcgttg
    15721 ccggatctga tggtcgctca gactcacacc cgcacgtctt tattcagttt ttcccgccag
    15781 atgcagggaa gccgtgaacc gctggtgtca ctgcttgagg gtctgcttga tggcgaaaat
    15841 atgaacgtga tgctgcgtgg tgtctatctc acctcttcgc ttcagcgtgg gcagatggat
    15901 gatatattca cccagtctgc cgcccgccag taccggctgg gcaataaccc actggcgtcc
    15961 tggcccctgg tggacaccgc gccttatttc acccgcagcc tgttcccgca ggcattactc
    16021 gcagagccta atctggcaac agagagccgc gcctggctga tacgttcccg tcgccgcctg
    16081 acagttttct ctgccacagg cggcgtggca gcacttctgc tcatcaccgg ctggcatcac
    16141 tattacaacg gtaactatca gtccggcatc accgtgctta agcaggccaa agcctttatg
    16201 gacgtgccgc ctccgcaggg ggaagatgac tttggcaacc tgcaactgcc gcttctgaac
    16261 ccggtacgcg atgccacact ggcctatggc gactggggcg accgcagccg tctggccgat
    16321 atgggactgt accagggacg acgtatcggg ccttatgtgg aacagaccta tctgcaactg
    16381 ctggagcaac gttacctgcc ctcgctgttt aacgggctgg tcaaagcgat gaacgccgcg
    16441 ccgccggaga gtgaagaaaa actcgcggtg ctgcgcgtaa tgcgaatgct ggaggacaaa
    16501 agcggacgta acaatgaggt ggtgaagcag tatatggcaa aacgctggag cgaaaaattc
    16561 cacggccagc gcgatatcca ggcacaactg atgtcccatc ttgactacgc gctggctcat
    16621 actgactggc atgcagagcg tcaggcgggc gacggtgacg ccatcagccg ctggacgcca
    16681 tatgacaagc ccgtggtatc agcacagaaa gaactgagca aactgcctgt ctaccagcgg
    16741 gtttaccaga gcctgaaaac gcgggcgctg ggcgttcttc ctgccgacct caatctgcgt
    16801 gaccaggtag ggccaacctt tgaccaggtg tttacatctg ccgatgacaa caaactggtt
    16861 gttccatagt ttcttacccg ttacggcctg caaagctatt ttgtaaaaca gcgcgatgaa
    16921 ctggttgaac tgacggcgat ggattcctgg gtacttaacc ttacccgcag cgtgaaatac
    16981 agtgacgccg accgcgcgga aatccagcgc cagttgaccg agcagtatat cagcgactac
    17041 accgccacct ggcgggccgg gatggacaat ctgaatatcc gcaattttga gtccatcgga
    17101 caactgaccg gggcgctgga gcaggttatc agcggcgacc agcctttgca gcgggcgctg
    17161 accgtcctgc gtgacaacac acagccaggc gtcttttctg aaaaactctc tgccaaagaa
    17221 cgggaggaag ccctggcaga gccggattac cagttactca cccgcctcgg gcatgaattc
    17281 gccccggaaa acagtaccct ggcagtacag aaagacaaag aaagcacgat gcaggccgtg
    17341 tatcagcaac tcaccgagtt gcaccgctac ctgctggcaa tccagaacgc gcctgtacca
    17401 gggaaatcgg cgctgaaagc cgtgcagtta cggcttgatc agaacagcag cgatccgata
    17461 ttcgccaccc gccagatggc aaaaacgctg cctgctccgc tcaaccgctg ggttggcaga
    17521 ctgactgacc aggcctggca tgtggtgatg gtggaggctg ttcattatat ggaagtggac
    17581 tggcgcgaca gcgtggtgaa accgtttaac gagcaactgg caaataacta tccgtttaat
    17641 ccgcgttctg cacaggatgc ctcactggat gccttcgaac gcttctttaa accggatggc
    17701 atactggata ccttctacca gcagaacctg aagctgttta tcgataatga cctgagtctg
    17761 gaggatggcg ataacaacgt cattattcgc gaagatatta ttgcgcaact ggaaactgcg
    17821 cagaaaatcc gtgacatctt cttcagcaaa cagaacggtc tgggaacatc ctttgccgtg
    17881 gaaacggtat cgctttcagg caataaacgc cgcagtgtac tgaaccttga cggtcagtta
    17941 gtcgattaca gccagggccg taactatacc gcccatctgg tctggcctaa caacatgcgc
    18001 gaaggcaacg aaagtaagct gacgctcatc ggcaccagcg gcaacgcgcc gcgcagtatc
    18061 agcttcagcg ggccgtgggc gcagttccgc ctgttcgggg ccggacaact gaccggagta
    18121 caggatggca actttaccgt gcgctttagc gtggacggtg gcgcgatgac ctaccgtgtg
    18181 cataccgaca cggaagataa cccgttcagc ggtgggttgt tcagccagtt tggtctgtca
    18241 gacacactgt actgaggagg cagggatgaa tagtaacgta ctgacacaaa ctatcgttac
    18301 cggcagtgac ccgcgcgggc tgccggaatt cagcgccatc cgcgaggaaa taaacaaagc
    18361 cagccacccg tcacagcctg agctgaactg gaaactggtg gagtcgctgg cgctggcgat
    18421 ttttaaagcc aacggtgtgg atttacacac cgccacctac tatacgcttg cccggacacg
    18481 gacacaggga ctggcgggat tctgcgaagg tgcggaactg ctggcggcaa tggtaagcca
    18541 cgactgggat aagttctggc cgcagggcgg cccggcgcgt actgaaatgc tggactggtt
    18601 taactcccga accggcaata ttctgcgtca gcaaatctcc tttgcggaat ccgacctacc
    18661 actgatctac cgcacagagc gggcattgca gcttatctgc gataagctcc agcaggtgga
    18721 actgaagcgc gttccgcgcg tggagaatct gctctatttt atgcagaaca cgcgtaaacg
    18781 gcttgaaccc cagctgaaga gtaacactga gaacgccgca cagaccacgg tcagaacgct
    18841 gatttatgcc ccggaaacac aggcatcttc cacaccagaa gcggtagtgc ctcccctgcc
    18901 cggcctgcct gagatgaaag tggaagtgcg cagtctgaca gagaatcccc cacaggccag
    18961 tgtgataaag caaggcagta cggtaagagg gtttatcgca gggatcgcct gttcagtggc
    19021 tgtcgcctca gcattgtggt ggtggcaggt ctatccggtg cagcagcaac tgttacaggt
    19081 taacgacacc gttcagggcg cagcaacggt gtggatggcc tcacctgaac tcgaaaacta
    19141 tgagcgcagg ctgcaacaac ttcttgatac ctccccggta cagccgctgg aaaccgggat
    19201 gcagatgatg cgtgttgccg acagtcgctg gccggaaagc ctgcaacagc aacaggcctc
    19261 gacacaatgg aatgaggcac tcaaaacccg cgcacagagt agcccgcagt tgcgtggctg
    19321 gttgcagacc cgccaggact tacatgcttt tgcagatcta gtgatgcagc gcgagaaaga
    19381 gggactaacc ctttcctata tcaaaaatgt catctggcag gcggagcggg gactggggca
    19441 ggaaacaccc gttgagtctc tgttgacgca gtaccatgat gcccgtgcgc agaagcagaa
    19501 tacagatgcg ctggaaaaac aaattaatga gcgactcgaa ggcgtgttaa gccgctggct
    19561 gctgctgaag aataacgtca tgccagaggc ggcaaccggt accacggccg aaaaataatt
    19621 atttaattaa aggagattat catggcaaat ataagttatt tatctttgag tggagagaca
    19681 caagggctaa tttcagcagg ttgctcaacg cttgattctg tcggaaacaa agcgcagcca
    19741 gaacataaag atcagatcat ggtttatgcg ttaatgcatt ccatctcaag aagtcaaaat
    19801 gtcaatcatc atgaattaat tatcaccaaa ccggttgata aatcctcacc attgctggca
    19861 aaagcactta gtgacaatga aaaaatggca atatgtgaat ttatactcta ccgaaccagt
    19921 aaagcgggta tttaccagcc ttattataaa ataaatctgt caaaagcccg aatatcaagt
    19981 attgattttg tcacaccgca tgctgtcctg gaaaaagaac tggaaccaca ggagagaatt
    20041 gcctttattt atgaagatat ttcctgggag catacgttag ccggtacgaa tgcaatgagt
    20101 aaatggcagg atcgtgtaca gtaacttact gtaataacat aataaattac tattgcggag
    20161 agataaaatg gctggtttaa ggaataacaa caacacacag aatgcacagt gggctgatta
    20221 tgtgggtgac attcttcggg gggctcagcc gataaaccag ctagtacctc agcaccctta
    20281 tcttaacgac gtcccattca ttgatgagtt aaggcatcag aacactcatc atgttattcc
    20341 cttgacactt gatgttgcaa aaaaaatact cagcccaata acatcatttg attacattca
    20401 ttttatcact acacatcctt caggtataaa agatacactc gcctggttag ttaacgcggg
    20461 taaattaatg actgagtttg atgacaatgg gaaaattata tttaacctta atgccttaaa
    20521 gtatacaaaa gcaagttact ttgaaatact tggagagaaa tatataaaaa tcacaacatc
    20581 cagcccctgg cttttagaaa agctcggtaa atatattttc tcttcacgag cgcctcaagt
    20641 tctggaactc gctattggct ggcgaggagc tttatctgaa tcaataaaag gagttaagtt
    20701 ctgtatctgg ttttcagtag cctggagaac catagaattt attatgagtt cagagcgaga
    20761 tctggttaat tttcttggcg atttttcaat ggatgtggcc aaagcagtta tagccggtgg
    20821 tgttgcaacc gctattggaa gtctggcttc ttttgcctgt gttagctttg gctttccagt
    20881 aattcttgtc ggaggagcaa ttttactgac agggatagtg tgtacagttg ttttaaatga
    20941 aatcgatgtt caatgccatt tatcagaaaa attaaaatat gcaattagag atggactaaa
    21001 acggcaacag gaacttgata aatggaaaag ggaaaacatg actccattta tgtatgttct
    21061 taacactcca cccgtgatat gaggattaac catgcgttta catgttaaat taaaagagtt
    21121 tctttcgatg ttttttatgg ccatattatt tttccctgca ttcaatgctt ctttgttttt
    21181 taccggagtt aaacctctat attcaataat aaaatgctcc acggaaatat tttatgattg
    21241 gagaatgttg attctgtgct tcggtttcat g
//
LOCUS       DAPOAV010000079        20123 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.079, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000079 DAPOAV010000000
VERSION     DAPOAV010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20123
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.079"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(151..897)
                     /gene="cutC"
                     /locus_tag="RN951_003322"
     CDS             complement(151..897)
                     /gene="cutC"
                     /locus_tag="RN951_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025309.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HDX2528277.1"
                     /translation="MALLEICCYSMECALTAQQNGADRVELCAAPKEGGLTPSLGVLK
                     SVRQRVTIPVHPIIRPRGGDFCYSDGEFAAILEDVRTVRELGFPGLVTGVLDVDGNVD
                     MPRMEKIMAAAGPLAVTFHRAFDMCANPLYTLNNLAELGIARVLTSGQKSDALQGLSK
                     IMELIAHRDAPIIMAGAGVRAENLHHFLDAGVLEVHSSAGAWQASPMRYRNQGLSMSS
                     DEHADEYSRYIVDGAAVAEMKGIIERHQAK"
     gene            complement(911..1477)
                     /locus_tag="RN951_003323"
     CDS             complement(911..1477)
                     /locus_tag="RN951_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416389.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDX2528278.1"
                     /translation="MANWQSIDELQDIASDLPRFIHALDELSRRLGLNITPLTADHIS
                     LRCHQNATAERWRRGFEQCGELLSENMINGRPICLFKLHEPVQVAHWQFSIVELPWPG
                     EKRYPHEGWEHIEIVLPGDPETLNARALALLSDEGLSLPGISVKTSSPKGEHERLPNP
                     TLAVTDGKTTIKFHPWSIEEIVASEQSA"
     gene            1693..3426
                     /gene="argS"
                     /locus_tag="RN951_003324"
     CDS             1693..3426
                     /gene="argS"
                     /locus_tag="RN951_003324"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HDX2528279.1"
                     /translation="MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVHFGDYQANGM
                     MAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALAS
                     DRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVG
                     DWGTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQ
                     SGDEYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKG
                     LAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVL
                     YYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLAD
                     LLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNML
                     AFEGNTAPYMQYAYTRVLSVFRKAEIDEEQLAAAPVIIREDREAQLAARLLQFEETLT
                     VVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGL
                     DTLGIETVERM"
     gene            3603..4091
                     /locus_tag="RN951_003325"
     CDS             3603..4091
                     /locus_tag="RN951_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416391.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme inhibitor LprI family protein"
                     /protein_id="HDX2528280.1"
                     /translation="MFKFLVLTLGIISCQAYAEDTVIVNDHDISAIKDCWQKNSDDDT
                     DVNVIKSCLRQEYNLVDAQLNKAYGEAYRYIEQVPRTGVKKPDTEQLNLLKKSQRAWL
                     DFRDKECELILSNEDVQDLSDPYSESEWLSCMIIQTNTRTRQLQLYRNSEDFYPSPLT
                     RG"
     gene            complement(4211..4603)
                     /gene="flhe"
                     /locus_tag="RN951_003326"
     CDS             complement(4211..4603)
                     /gene="flhe"
                     /locus_tag="RN951_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlhE"
                     /protein_id="HDX2528281.1"
                     /translation="MRTLLAILLFPLLVQAAGEGMWQASSVGITLNHRGESMSSAPLS
                     TRQPASGLMTLVAWRYQLIGPTPSGLRVRLCSQSRCVELEGQSGTTVAFSGIAAAEPL
                     RFIWEVPGGGRLIPPLKVQRNEVIVNYR"
     gene            complement(4603..6681)
                     /gene="flhA"
                     /locus_tag="RN951_003327"
     CDS             complement(4603..6681)
                     /gene="flhA"
                     /locus_tag="RN951_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HDX2528282.1"
                     /translation="MSNLAAMLRLPANLKSTQWQILAGPILILLILSMMVLPLPAFIL
                     DLLFTFNIALSIMVLLVAMFTQRTLEFAAFPTILLFTTLLRLALNVASTRIILMEGHT
                     GAAAAGKVVEAFGHFLVGGNFAIGIVVFVILVIINFMVITKGAGRIAEVGARFVLDGM
                     PGKQMAIDADLNAGLIGEDEAKKRRSEVTQEADFYGSMDGASKFVRGDAIAGILIMVI
                     NIVGGLLVGVLQHGMSMGHAAESYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQD
                     VGEQMVNQLFSNPSVMLLSAAVLGLLGLVPGMPNLVFLLFTAGLLGLAWWIRGREQKA
                     PAEPKPVKMAENNTVVEATWNDVQLEDSLGMEVGYRLIPMVDFQQDGELLGRIRSIRK
                     KFAQEMGFLPPVVHIRDNMDLQPARYRILMKGVEIGSGDAYPGRWLAINPGTAAGTLP
                     GEATVDPAFGLNAIWIESALKEQAQIQGYTVVEASTVVATHLNHLISQHAAELFGRQE
                     AQQLLDRVAQEMPKLTEDLVPGVVTLTTLHKVLQNLLDEKVPIRDMRTILETLAEHAP
                     IQSDPHELTAVVRVALGRAITQQWFPGKDEVHVIGLDTPLERLLLQALQGGGGLEPGL
                     ADRLLAQTQEALSRQEMLGAPPVLLVNHALRPLLSRFLRRSLPQLVVLSNLELSDNRH
                     IRMTATIGGK"
     gene            complement(6674..7822)
                     /gene="flhB"
                     /locus_tag="RN951_003328"
     CDS             complement(6674..7822)
                     /gene="flhB"
                     /locus_tag="RN951_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FlhB"
                     /protein_id="HDX2528283.1"
                     /translation="MSDESDDKTEAPTPHRLEKAREEGQIPRSRELTSLLILLVGVSV
                     IWFGGVSLARRLSGMLSAGLHFDHSIINDPNLILGQIILLIREAMLALLPLISGVVLV
                     ALISPVMLGGLVFSGKSLQPKFSKLNPLPGIKRMFSAQTGAELLKAILKTILVGSVTG
                     FFLWHHWPQMMRLMAESPITAMGNAMDLVGLCALLVVLGVIPMVGFDVFFQIFSHLKK
                     LRMSRQDIRDEFKQSEGDPHVKGRIRQMQRAAARRRMMADVPKADVIVNNPTHYSVAL
                     QYDENKMSAPKVVAKGAGLVALRIREIGAENNVPTLEAPPLARALYRHAEIGQQIPGQ
                     LYAAVAEVLAWVWQLKRWRLAGGQRPVQPTHLPVPEALDFINEKPTHE"
     gene            complement(8024..8668)
                     /gene="cheZ"
                     /locus_tag="RN951_003329"
     CDS             complement(8024..8668)
                     /gene="cheZ"
                     /locus_tag="RN951_003329"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase CheZ"
                     /protein_id="HDX2528284.1"
                     /translation="MMQPSIKPADEHSAGDIIARIGSLTRMLRDSLRELGLDQAIAEA
                     AEAIPDARDRLYYVVQMTAQAAERALNSVEASQPHQDQMEKSAKALTQRWDDWFADPI
                     DLADARELVTDTRQFLADVPAHTSFTNAQLLEIMMAQDFQDLTGQVIKRMMDVIQEIE
                     RQLLMVLLENIPEQESRPKRENQSLLNGPQVDTSKAGVVASQDQVDDLLDSLGF"
     gene            complement(8679..9068)
                     /gene="cheY"
                     /locus_tag="RN951_003330"
     CDS             complement(8679..9068)
                     /gene="cheY"
                     /locus_tag="RN951_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002210873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis response regulator CheY"
                     /protein_id="HDX2528285.1"
                     /translation="MADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALN
                     KLQAGGYGFVISDWNMPNMDGLELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQAG
                     ASGYVVKPFTAATLEEKLNKIFEKLGM"
     gene            complement(9083..10132)
                     /gene="cheB"
                     /locus_tag="RN951_003331"
     CDS             complement(9083..10132)
                     /gene="cheB"
                     /locus_tag="RN951_003331"
                     /EC_number="3.1.1.61"
                     /EC_number="3.5.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate methylesterase/protein
                     glutamine deamidase"
                     /protein_id="HDX2528286.1"
                     /translation="MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDL
                     IKKFNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRALELGAI
                     DFVTKPQLGIREGMLAYNEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIA
                     IGASTGGTEAIRHVLQPLPLSSPALLITQHMPPGFTRSFADRLNKLCQIGVKEAEDGE
                     RVLPGHAYIAPGDRHMELSRSGANYQIKIHDGPAVNRHRPSVDVLFHSVAKQAGRNAV
                     GVILTGMGNDGAAGMLAMRQAGAWTLAQNEASCVVFGMPREAINMGGVCEVVDLSQVS
                     QQMLAKISAGQAIRI"
     gene            complement(10135..10995)
                     /gene="cheR"
                     /locus_tag="RN951_003332"
     CDS             complement(10135..10995)
                     /gene="cheR"
                     /locus_tag="RN951_003332"
                     /EC_number="2.1.1.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HDX2528287.1"
                     /translation="MTSSLPCGQTSLLLQMTERLALSDAHFRRISQLIYQRAGIVLAD
                     HKRDMVYNRLVRRLRSLGLTDFGHYLNLLESNQHSGEWQAFINSLTTNLTAFFREAHH
                     FPLLADHARRRSGEYRVWSAAASTGEEPYSIAMTLADTLGTAPGRWKVFASDIDTEVL
                     EKARSGIYRHEELKNLTPQQLQRYFMRGTGPHEGLVRVRQELANYVDFAPLNLLAKQY
                     TVPGPFDAIFCRNVMIYFDQTTQQEILRRFVPLLKPDGLLFAGHSENFSHLERRFTLR
                     GQTVYALSKD"
     gene            complement(11014..12615)
                     /gene="tap"
                     /locus_tag="RN951_003333"
     CDS             complement(11014..12615)
                     /gene="tap"
                     /locus_tag="RN951_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein IV"
                     /protein_id="HDX2528288.1"
                     /translation="MFNRIRISTTLFLILILCGILQIGSNGMSFWAFRDDLQRLNQVE
                     QSNQQRAALAQTRAVMLQASTALNKAGTLTALSYPADDIKTLMTTARASLTQSTTLFK
                     SFMAMTAGNEHVRGLQKETEKSFARWHNDLEHQATWLESNQLSDFLTAPVQGSQNAFD
                     VNFEAWQLEINHVLEAASAQSQRNYQISALVFISMIIVAAIYISSALWWTRKMIVQPL
                     AIIGSHFDSIAAGNLARPIAVYGRNEITAIFASLKTMQQALRGTVSDVRKGSQEMHIG
                     IAEIVAGNNDLSSRTEQQAASLAQTAASMEQLTATVGQNADNARQASELAKNAATTAQ
                     AGGVQVSTMTHTMQEIATSSQKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGF
                     AVVAGEVRNLASRSAQAAKEIKGLIEESVNRVQQGSKLVNNAAATMIDIVSSVTRVND
                     IMGEIASASEEQQRGIEQVAQAVSQMDQVTQQNASLVEEAAVATEQLANQADHLSSRV
                     AVFTLEEHEVARHESVQLQIAPVVS"
     gene            complement(12661..14322)
                     /gene="tar"
                     /locus_tag="RN951_003334"
     CDS             complement(12661..14322)
                     /gene="tar"
                     /locus_tag="RN951_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein II"
                     /protein_id="HDX2528289.1"
                     /translation="MINRIRVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSN
                     QLREQQGELTSTWDLMLQTRINLSRSAVRMMMDSSNQQSNAKVELLDSARKTLAQAAT
                     HYKKFKSMAPLPEMVATSRNIDEKYKNYYTALTELIDYLDYGNTGAYFAQPTQGMQNA
                     MGEAFAQYALSSEKLYRDIVTDNADDYRFAQWQLAVIALVVVLILLVAWYGIRRMLLT
                     PLAKIIAHIREIAGGNLANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIY
                     AGTREIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADNARQASQLAQSASDT
                     AQHGGKVVDGVVKTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGR
                     GFAVVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMNNIVNAVTRV
                     TDIMGEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQ
                     AVSAFRLAASPLTNKPQTPSRPASEQPPAQPRLRIAEQDPNWETF"
     gene            complement(14467..14970)
                     /gene="cheW"
                     /locus_tag="RN951_003335"
     CDS             complement(14467..14970)
                     /gene="cheW"
                     /locus_tag="RN951_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HDX2528290.1"
                     /translation="MTGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQ
                     VTRIANTPAFIKGVTNLRGVIVPIVDLRIKFSQVDVDYNDNTVVIVLNLGQRVVGIVV
                     DGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLD
                     SAASEVA"
     gene            complement(14991..16955)
                     /gene="cheA"
                     /locus_tag="RN951_003336"
     CDS             complement(14991..16955)
                     /gene="cheA"
                     /locus_tag="RN951_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HDX2528291.1"
                     /translation="MSMDISDFYQTFFDEADELLADMEQHLLVLQPEAPDAEQLNAIF
                     RAAHSIKGGAGTFGFSVLQETTHLMENLLDEARRGEMQLNTDIINLFLETKDIMQEQL
                     DAYKQSQEPDAASFDYICQALRQLALEAKGETPSAVTRLSVVAKSEPQDEQSRSQSPR
                     RIILSRLKAGEVDLLEEELGHLTTLTDVVKGADSLSAILPGDIAEDDITAVLCFVIET
                     DQITFETVEVSPKISTPPVLKLAAEQAPTGRVEREKTTRSNESTSIRVAVEKVDQLIN
                     LVGELVITQSMLAQRSSELDPVNHGDLITSMGQLQRNAHDLQESVMSIRMMPMEYVFS
                     RYPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHGIELPEKR
                     LAAGKNSVGNLILSAEHQGGNICIEVTDDGAGLNRERILAKAASQGLTVSENMSDDEV
                     AMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGTGTTIRILLPLT
                     LAILDGMSVRVADEVFILPLNAVMESLQPREADLHPLAGGERVLEVRGEYLPIVELWK
                     VFNVAGAKTEATQGIVVILQSGGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAAT
                     ILGDGSVALIVDVSALQAINREQRMANTAA"
     gene            complement(16960..17886)
                     /gene="motB"
                     /locus_tag="RN951_003337"
     CDS             complement(16960..17886)
                     /gene="motB"
                     /locus_tag="RN951_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein MotB"
                     /protein_id="HDX2528292.1"
                     /translation="MKNQAHPIIVVKRRKAKSHGAAHGSWKIAYADFMTAMMAFFLVM
                     WLISISSPKELIQIAEYFRTPLATAVTGGDRISNSESPIPGGGDDYTQSQGEVNKQPN
                     IEELKKRMEQSRLRKLRGDLDQLIESDPKLRALRPHLKIDLVQEGLRIQIIDSQNRPM
                     FRTGSADVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPYASGEKGYSNWELSADRA
                     NASRRELMVGGLDSGKVLRVVGMAATMRLSDRGPDDAVNRRISLLVLNKQAEQAILHE
                     NAESQNEPVSALEKPEVAPQVSVPTMPSAEPR"
     gene            complement(17883..18770)
                     /gene="motA"
                     /locus_tag="RN951_003338"
     CDS             complement(17883..18770)
                     /gene="motA"
                     /locus_tag="RN951_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor stator protein MotA"
                     /protein_id="HDX2528293.1"
                     /translation="MLILLGYLVVLGTVFGGYLMTGGSLGALYQPAELVIIAGAGIGS
                     FIVGNNGKAIKGTLKALPLLFRRSKYTKAMYMDLLALLYRLMAKSRQMGMFSLERDIE
                     NPRESEIFASYPRILADSVMLDFIVDYLRLIISGHMNTFEIEALMDEEIETHESEAEV
                     PANSLALVGDSLPAFGIVAAVMGVVHALGSADRPAAELGALIAHAMVGTFLGILLAYG
                     FISPLATVLRQKSAETSKMMQCVKVTLLSNLNGYAPPIAVEFGRKTLYSSERPSFIEL
                     EEHVRAVKNPQQQTTTEEA"
     gene            complement(18897..19475)
                     /gene="flhC"
                     /locus_tag="RN951_003339"
     CDS             complement(18897..19475)
                     /gene="flhC"
                     /locus_tag="RN951_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhC"
                     /protein_id="HDX2528294.1"
                     /translation="MSEKSIVQEARDIQLAMELITLGARLQMLESETQLSRGRLIKLY
                     KELRGSPPPKGMLPFSTDWFMTWEQNVHASIFCNAWQFLLKTGLCNGVDAVIKAYRLY
                     LEQCPQAEEGPLLALTRAWTLVRFVESGLLQLSSCNCCGGNFITHAHQPVGSFACSLC
                     QPPSRAVKRRKLSQNPADIIPQLLDEQRVQAV"
     gene            complement(19478..19828)
                     /gene="flhD"
                     /locus_tag="RN951_003340"
     CDS             complement(19478..19828)
                     /gene="flhD"
                     /locus_tag="RN951_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416406.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhD"
                     /protein_id="HDX2528295.1"
                     /translation="MHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMAT
                     TLAALTLPQMVKLAETNQLVCHFRFDSHQTITQLTQDSRVDDLQQIHTGIMLSTRLLN
                     DVNQPEEALRKKRA"
BASE COUNT         4793 a         5550 c         4928 g         4852 t
ORIGIN      
        1 acaacgctat gcgcactgtc acccgctcaa cagatcacgg ttatcgttcg ttttttatac
       61 tgttcaggga taaaaaaagg cccctgttga aattgcaggg gcctggtacg agcaagcatc
      121 atattgggcg acatgatgca acggtaaaaa tcatttggcc tgatggcgtt caatgattcc
      181 tttcatttca gcaaccgccg ccccgtctac gatataacgc gaatactcgt ccgcgtgttc
      241 atctgatgac atggacaatc cttgattacg ataacgcatc ggtgaggctt gccacgctcc
      301 cgcggagcta tggacttcca gcactccggc atcgaggaag tggtgcaggt tttctgcacg
      361 gactcctgct ccggccataa tgattggagc atcacgatgg gcaataagtt ccataatttt
      421 tgataaacct tgcagtgcgt ctgatttttg ccctgatgtc agtacccggg caatgcccaa
      481 ttccgcaaga ttattgagtg tatataaagg gttagcgcac atatcgaagg cgcgatgaaa
      541 agtcactgcc agcggaccgg cagcagccat tattttttcc attcgtggca tatcgacatt
      601 cccgtcaaca tcgagaacgc ccgtcaccag tccaggaaaa cctaattcgc ggaccgtgcg
      661 cacatcctca agaatggcgg caaactcacc gtcgctgtag caaaaatcac caccgcgtgg
      721 gcgaattatc ggatgcacag ggatcgtcac ccgctggcgc acggatttca gtacacccaa
      781 cgacggcgtt aagcccccct cttttggggc tgcgcataat tcaactctgt ctgcgccgtt
      841 ttgctgcgcc gttagtgcac attccatgct gtaacagcaa atttccagta atgccatttt
      901 tactccttaa ttacgccgac tgctcgctgg caacgatctc ttcaatggac cacggatgaa
      961 acttaatagt tgttttgcca tcggtgaccg ccagcgtcgg attcggtaat cgctcatgct
     1021 caccttttgg cgaactggtt ttcactgaga tccccggtag gctgagtcct tcatcagaaa
     1081 gcaatgccag cgcacgggca ttcagcgttt ctggatcacc cggcagaacg atttcaatat
     1141 gttcccaacc ttcgtgtggg taacgttttt ccccgggcca cggtagctcc acaatagaaa
     1201 actgccagtg cgcaacctgt accggttcat gcaatttaaa cagacaaatc ggtctgccat
     1261 tgatcatatt ttctgacaaa agctcgccac actgttcaaa cccgcgacgc cagcgttcag
     1321 cagtggcgtt ttgatggcaa cgcaaagaaa tgtgatcggc agtcagcgga gtgatattca
     1381 accccagacg gcgggaaagt tcatctaatg cgtggataaa tcgcggtaaa tccgatgcaa
     1441 tatcctgcag ctcgtcgata gattgccagt tcgccataat cactcttcgt ctttcagtaa
     1501 aagcgttaat ttaccctgtt gccctgtgcc aaccaaccgc tgatttcacg ccgcttctga
     1561 tgcaatagtg aaaacggcaa tacgccacgc gcacgttgct gacgaaaaca gccatttgca
     1621 gtatactccc gccctaattt ctttaactgg tgcgggcaat ttttgctcgc ttcatcaatg
     1681 taaggtattc cggtgaatat tcaggctctt ctctcagaaa aagtccgtca ggccatgatt
     1741 gcggcaggcg cgcctgcgga ttgcgaaccg caggttcgtc agtcagcaaa agttcatttc
     1801 ggcgactatc aggctaacgg catgatggca gttgctaaaa aactgggtat ggcaccgcga
     1861 caattagcag agcaggtgct gactcatctg gatcttaacg gtatcgccag caaagttgag
     1921 atcgccggtc caggctttat caacattttc cttgatccgg cattcctggc tgaacatgtt
     1981 cagcaggcgc tggcgtccga tcgtctcggt gttgctacgc cagaaaaaca gaccattgtg
     2041 gttgactact ctgcgccaaa cgtggcgaaa gagatgcatg tcggtcacct gcgctctacc
     2101 attattggtg acgcagcagt gcgtactctg gagttcctcg gtcacaaagt gattcgcgca
     2161 aaccacgtcg gcgactgggg cactcagttc ggtatgctga ttgcatggct ggaaaagcag
     2221 cagcaggaaa acgccggtga aatggagctg gctgaccttg aaggtttcta ccgcgatgcg
     2281 aaaaagcatt acgatgaaga tgaagagttc gccgagcgcg cacgtaacta cgtggtaaaa
     2341 ctgcaaagcg gtgacgaata tttccgcgag atgtggcgca aactggtcga catcaccatg
     2401 acgcagaacc agatcaccta cgatcgtctc aacgtgacgc tgacccgtga tgacgtgatg
     2461 ggcgaaagcc tctacaaccc gatgctgcca ggaattgtgg cggatctcaa agccaaaggt
     2521 ctggcagtag aaagcgaagg ggcgaccgtc gtattccttg atgagtttaa aaacaaggaa
     2581 ggcgaaccga tgggcgtgat cattcagaag aaagatggcg gctatctcta caccaccact
     2641 gatatcgcct gtgcgaaata tcgttatgaa acactgcatg ccgatcgcgt gctgtattac
     2701 atcgactccc gtcagcatca acacctgatg caggcatggg cgatcgtccg taaagcaggc
     2761 tatgtaccgg aatccgtacc gctggaacac cacatgttcg gcatgatgct gggtaaagac
     2821 ggcaaaccgt tcaaaacccg cgcgggtggt acagtgaaac tggccgatct gctggatgaa
     2881 gccctggaac gtgcacgccg tctggtggca gaaaagaacc cggatatgcc agccgacgag
     2941 ctggaaaaac tggctaacgc ggttggtatt ggtgcggtga aatatgcgga tctctccaaa
     3001 aaccgcacca cggactacat cttcgactgg gacaacatgc tggcgtttga gggtaatacc
     3061 gcgccataca tgcagtatgc atacacgcgt gtattgtccg tgttccgtaa agcagaaatt
     3121 gacgaagagc aactggctgc agctccggtt atcatccgtg aagatcgtga agcgcaactg
     3181 gcagctcgcc tgctgcagtt tgaagaaacc ctcaccgtgg ttgcccgtga aggcacgccg
     3241 catgtaatgt gtgcttacct gtacgatctg gccggtctgt tctctggctt ctacgagcac
     3301 tgcccgatcc tcagcgcaga aaacgaagaa gtgcgtaaca gccgtctaaa actggcacaa
     3361 ctgacggcga agacgctgaa gctgggtctg gatacgctgg gtattgagac tgtagagcgt
     3421 atgtaatcga tttttcgtga gagtgaagcc tgatcagggt tagccgatca ggctttttta
     3481 ttgccatcta aatgtattct gaaaatggac atgccattgt tttctcactg ttggataaga
     3541 ggccagaagc gtaatatccg gccccaggga aacgataacg gttgaattta aggaataccg
     3601 cagtgtttaa atttcttgta ttaacattag gcattatctc ttgccaggct tacgcagaag
     3661 atacggttat agtaaacgac catgacattt cagccatcaa agattgttgg caaaaaaatt
     3721 cagatgatga tactgacgtt aacgtgatca aatcatgcct gcgacaagaa tacaatctcg
     3781 tcgatgcgca attaaataaa gcctatggtg aagcttatcg ttatatagaa caagtgccac
     3841 gcacaggtgt aaaaaaacct gataccgaac aacttaactt gcttaaaaaa tcacagcgag
     3901 cctggctgga ttttagggac aaagaatgtg aattaatcct ttcaaatgag gacgttcagg
     3961 atttaagtga cccttattct gaatcagaat ggctctcatg tatgatcata cagaccaata
     4021 cgcgaactcg ccagttgcag ctataccgta actctgaaga tttttatcca agccctttga
     4081 caagaggata attcacatct ttttggcatg ttttgttgca agctattcct gataaataat
     4141 tgcaacaaga catcgagcct ttttcactga gttattaaac atactcgcga gcgcgtaatt
     4201 tttttgtcct tcagcgataa ttcacaatca cttcattacg ttgtaccttt agcggtggaa
     4261 ttaaccgccc accgcctggc acttcccaga taaatcgcaa cggttctgct gccgctatac
     4321 cggaaaaggc cacggtggtt ccgctctgcc cctctaattc gacacaacga gattgcgaac
     4381 acaagcgaac ccgcagtcct gaaggtgtcg ggccgataag ctgataacgc cacgctacca
     4441 gcgtcatcaa tcctgaagca ggttgtcgcg tagaaagagg cgcagacgac atcgactcac
     4501 cgcgatgatt tagcgtaatt cctacactac ttgcctgcca catcccctcc ccggcggctt
     4561 gcaccagcag cggaaacaat aatattgcta ataaggttct cattatttgc cgccaattgt
     4621 cgccgtcatg cggatatgtc ggttatcaga cagttccaga ttcgacagga ccactaactg
     4681 cggcaagctg cggcgcagga agcgagacaa taatggtcgc agcgcgtggt tcaccaacaa
     4741 tactggcggc gcacccagca tctcctgacg ggatagcgct tcctgagttt gcgccagtaa
     4801 acgatccgcc agccctggct ccagtcctcc cccgccctgc agcgcctgta gtaacaaacg
     4861 ttccagcggt gtatcgaggc caataacatg gacttcatct ttgccaggaa accactgctg
     4921 ggtaatcgcc cgtcccaacg ccacgcgcac gacggcggtt aattcatgtg gatcgctttg
     4981 gatgggcgca tgttccgcca gcgtttcgag aatggtgcgc atatcgcgaa tcggtacttt
     5041 ttcatcgagg agattttgca gcactttatg cagtgtggtg agcgtgacga cgccaggaac
     5101 gagatcttcc gtcagctttg gcatctcctg ggcgacgcga tccaacagct gttgcgcctc
     5161 ctgacgacca aacagctctg cggcatgctg gctaatgagg tggttaagat gcgttgctac
     5221 caccgtgctg gcctcaacca ctgtgtaccc ctgaatctgc gcctgttctt ttagcgcact
     5281 ttcaatccag atagcattca ggccaaatgc cggatcgacg gtcgcctcac caggtaacgt
     5341 cccggcagcg gttccagggt taatcgccag ccagcgcccc ggataagcat caccactgcc
     5401 aatctccacg cctttcatca aaatgcgata gcgggcaggt tgcagatcca tattgtcgcg
     5461 aatgtgcacc actggcggca gaaatcccat ctcctgggca aatttcttgc ggatactgcg
     5521 tatacggccc aacaactcac catcctgctg gaaatcgacc atcgggatca gtcgataacc
     5581 cacttccatt cccagagaat cttccagttg tacatcgttc cacgtcgctt cgacaacggt
     5641 attattctct gccattttta ccggtttggg ttcggcaggc gctttttgtt cgcgtccgcg
     5701 tatccaccag gccagcccga gcaatccggc agtgaacagc aaaaatacca ggttcggcat
     5761 tccaggcacc aggccgagta aaccgagcac ggcggcgctt aacaacataa cgcttgggtt
     5821 actgaaaagc tgattcacca tctgctcgcc aacatcctga tcggtgctga cacgcgtaac
     5881 gatgaccccc gcggcggtag aaatcaccag cgccggaatt tgtgccacca gaccgtcgcc
     5941 aatggtcaat agcgtataac tttccgccgc gtgtcccatg ctcatgccat gttgcagcac
     6001 gccgaccagc aacccgccga caatgttaat gaccatgatg aggatcccgg cgatggcatc
     6061 gccgcgaaca aacttacttg ccccgtccat tgagccgtaa aaatcggctt cctgagtcac
     6121 ttcggagcgg cgttttttcg cctcatcttc accaatcaat ccggcgttaa ggtcggcgtc
     6181 aatcgccatc tgcttacccg gcataccatc gagaacaaag cgcgcaccca cttctgcgat
     6241 acgcccggca cctttggtaa tgaccataaa gttgatgatc acgagaatga caaacaccac
     6301 gataccgata gcgaaattgc caccaacgag gaagtgaccg aacgcttcga ccaccttccc
     6361 tgccgccgcc gcgccggtat gcccttccat taaaatgata cgggttgaag ccacgttaag
     6421 tgccagacgc aacagcgtgg taaacaacag aatggtcgga aacgcagcaa actcaagcgt
     6481 gcgctgggta aacatcgcca ccagcaacac catgatcgac aaggcaatat tgaaggtaaa
     6541 caacaggtcg agtatgaatg cgggcagtgg cagcaccatc atcgacaaga tcaacaggat
     6601 caaaatcggt ccggcaagga tctgccattg tgtcgatttc aggtttgcgg gcaggcgcag
     6661 catcgcggcc agattactca tgggtcggtt tctcgttaat aaaatccagg gcttccggca
     6721 ccggaagatg agtaggttgt acagggcgct gtccaccagc cagacgccag cgtttcagtt
     6781 gccagaccca ggccagcact tccgccaccg cggcgtacag ttgacccggg atttgttgac
     6841 caatctccgc atgtcgatac agcgctcgcg ccagcggcgg cgcttcaagc gtcgggacgt
     6901 tattttcagc gccaatttca cgaatgcgca gcgcgaccag ccctgcacct ttagcgacca
     6961 ctttcggtgc gctcattttg ttttcgtcat actgcaacgc taccgaatag tgggtcgggt
     7021 tattgacaat gacatccgct ttcggcacat cggccatcat ccgacgccgt gcagcagctc
     7081 gctgcatctg acggatccgc cctttaacat gagggtcacc ttcgctttgt ttgaactcat
     7141 cacgaatatc ctgccgtgac atacgcagct ttttcaggtg gctgaatatt tggaaaaaga
     7201 cgtcaaatcc caccattgga atgacaccaa gcaccaccag cagtgcgcat agccctacca
     7261 aatccatcgc attacccatg gcggtaatcg gagactcggc catcaagcgc atcatctgcg
     7321 gccagtgatg ccagagaaaa aaccccgtca cgctgccaac caggatggtt ttcaaaattg
     7381 ctttaagcaa ctccgcgcca gtctgagccg agaacatccg tttaatgccc ggtagcgggt
     7441 tgagtttgga aaacttcggc tgcaaggatt tgccgctaaa taccaaccct cccagcatga
     7501 ccggagaaat gagcgccacc agcaccacgc cgctaatcag cggcagcagc gccagcatgg
     7561 cttctctgat cagcagaata atctgcccga ggatcagatt cgggtcattg ataatactgt
     7621 gatcaaaatg cagcccagcg gagagcatgc ccgacaatcg acgggccagc gacacaccgc
     7681 caaaccagat aacactaacg cccaccagca aaatcagcag tgaggtcagt tcacgggaac
     7741 gcgggatttg cccctcttcc cgcgcttttt ctagtcggtg aggtgtgggg gcttctgttt
     7801 tgtcgtcgct ctcgtcagac acgtcgccaa tcctggaaag agtattaagc gtgaatgatg
     7861 ccagagcgca aagcgttcaa tggtttgagt aaggggcaaa acaggcggga tttagggctt
     7921 ttgctgccac acatcaagca tagtgtgcgt ttgtcggatg cggcgtcatc gccttatcag
     7981 accgcctgat atgacgtggt cacgccacat caggcaatac aaatcaaaat ccaagactat
     8041 ccaacaaatc gtccacctga tcctgactgg ctaccacacc ggctttgctg gtatcgacct
     8101 gaggtccatt aagcaaactc tggttttcac gttttggacg cgactcctgt tccgggatgt
     8161 tttccaacag caccatcagc aactggcgtt cgatctcctg aatgacatcc atcatccgct
     8221 taatgacctg cccggtgaga tcctgaaaat cctgcgccat catgatttcc agcagttgcg
     8281 cgttagtaaa gctggtatgc gcgggtacat ctgccagaaa ttgtcgtgta tctgttacca
     8341 gttcacgggc gtcggcaagg tcaatcggat cggcaaacca gtcatcccaa cgttgggtta
     8401 acgcttttgc tgatttctcc atttgatcct gatgcggttg tgacgcctca acactgttca
     8461 gcgcccgctc cgcagcctgg gcggtcatct gcacaacata gtacaaacga tcgcgcgcat
     8521 cggggatggc ttccgccgct tcggcaatgg cctgatccag ccccagttcc cgcaaactgt
     8581 cgcgcagcat acgcgtcagg ctgccgatgc gcgcaatgat atcgccagct gaatgctcgt
     8641 cagcaggttt gattgatggt tgcatcatag tcgcatcctc acatgcccag tttctcaaag
     8701 attttgttga gtttttcctc cagcgtcgcg gcggtaaatg gcttcaccac atagccactg
     8761 gcccccgctt gcgccgcagc aatgatgttc tctttcttcg cttctgcagt caccattaac
     8821 actggcaatg ccgacatcgc gccatccgca cgaattgttt tcagcaattc caggccatcc
     8881 atattgggca tgttccagtc ggagataaca aatccataac cgcctgcctg caacttattg
     8941 agagcgtcga cgccatcttc cgcttcctca acattattga atcccagctc tttcagcagg
     9001 ttacgcacta tgcgtcgcat ggtggaaaag tcatccacaa ccaaaaattt aagttcttta
     9061 tccgccattt cacactcctg atttaaatac gtatcgcctg tccggcacta atttttgcca
     9121 acatttgctg gcttacctgg ctaagatcga ccacttcgca gacaccaccc atattgatag
     9181 cctcgcgcgg catgccgaac accacgcaac ttgcttcgtt ttgcgcaagg gtccatgccc
     9241 ccgcctgacg catcgccaac attcccgccg cgccgtcgtt gcccataccg gtcaggatca
     9301 ccccaaccgc attacgcccc gcctgtttgg cgacagaatg gaacaacaca tctaccgaag
     9361 gccgatgacg gttaaccgcc gggccatcgt gaattttgat ttggtaattt gcgccactac
     9421 gcgacagctc catatgccga tcgcccggcg caatataggc atgccccggc aagacacgtt
     9481 ctccgtcttc ggcttcttta accccgatct ggcaaagctt attaagtctg tcggcaaaag
     9541 agcgggtgaa accgggcggc atatgctggg taattaacag tgccgggctg gaaagcggca
     9601 acggttgcag tacgtgacga attgcctcag ttccacccgt tgaagcacca atcgcaatca
     9661 gtttttcaga actcaacaac ggccccgcct tcagcgttgt cggtgccgac aatggcttat
     9721 gtgctgcaag gctcgccttt gctgccgtac gcaccttttc agcaatcatt tcgttatacg
     9781 ccagcatacc ttcgcgaata cccagttgcg gtttggtgac aaaatctatc gcccccagct
     9841 ccagcgcgcg cagcgtgact tctgaccctt tgccggtcag ggaagaaacc atcacaacgg
     9901 gcattggacg caaacgcatt aatttttcga ggaaatccag tccgtccatc cgcggcattt
     9961 caacatccag cgtcagcaca tcgggattga atttcttaat caagtcacgc gcgaccagcg
    10021 gatcaggcgc ggtcgccacc atttccatgt cgctatggct gttgatgatt tctgtcatga
    10081 tctggcgcat cagtgccgaa tcatcgacag ataacaccct gattttgctc atcgttaatc
    10141 cttacttagc gcatacaccg tctgaccacg cagcgtgaag cggcgctcaa ggtggctaaa
    10201 gttttcagag tgacccgcaa acagcaatcc gtcgggttta aggagcggaa caaagcggcg
    10261 caaaatctcc tgctgggtag tttgatcgaa gtagatcatg acgttacgac agaagatcgc
    10321 atcaaacggc cccggcacgg tgtactgttt cgccagtaga ttcagcgggg caaaatcaac
    10381 atagttcgcc agctcctgac gcacgcgtac cagcccttca tgcggccccg tccctcgcat
    10441 gaaataccgt tgcagttgct gcggcgtcag gtttttcaac tcttcatggc gatagatacc
    10501 gcttctggct ttttccagca cttcggtgtc gatatcactg gcaaacactt tccagcgtcc
    10561 gggcgcggtg cccaatgtgt cagccagcgt catcgcaatg ctgtacggct cttcgccggt
    10621 cgaagccgcc gcgctccata cgcgatactc gccagaacgg cgacgtgcgt gatccgcgag
    10681 cagagggaaa tgatgtgcct cacggaaaaa tgccgtcaga ttcgtggtca gcgaattgat
    10741 aaacgcctgc cactcaccgc tgtgctgatt agattccagc aagttcagat aatgaccgaa
    10801 atccgtcagt cccagcgaac gcaaacgacg aaccagtcgg ttgtaaacca tgtcgcgttt
    10861 atggtcagcc agaacgatcc cggctcgttg atagatcaat tgacttatcc gccgaaaatg
    10921 cgcgtcggaa agcgccaggc gctcggtcat ctgtaacaat aaagacgttt gcccacaggg
    10981 cagagatgaa gtcatagcgc cttctcaatc acttcaggat accactggcg caatttgtaa
    11041 ctgcaccgac tcatgtcgtg ctacttcatg ttcttcaagg gtaaataccg ccacacgcga
    11101 cgaaagatgg tcggcctgat tcgccagttg ttccgttgcc accgccgctt cttctaccag
    11161 cgaggcgttc tgctgagtca cctgatccat ctggctgaca gcctgtgcaa cctgctcaat
    11221 cccccgctgt tgttcttccg acgcagaggc aatttctccc ataatgtcgt tcacgcgggt
    11281 caccgaactg acaatatcga tcatggtcgc ggcggcgtta ttcaccagtt tcgaaccctg
    11341 ctggacacga ttgactgact cttcgatcag ccctttgatc tcttttgctg cctgcgcgct
    11401 acggctggca agattgcgca cttcacctgc cactaccgca aaaccacgcc cctgctctcc
    11461 ggcgcgagcc gcttccactg ccgcattcag ggccagaata ttggtctgga aagcaattcc
    11521 gtcgataacg ctgataatgt cgccaatttt ttgcgagctg gtggcgatct cctgcatggt
    11581 gtgagtcatg gtactgacct gaacaccgcc cgcctgcgcc gttgtcgcgg cattttttgc
    11641 cagttccgac gcctgtcgtg cgttatcggc gttttgccct accgtggcgg ttaattgctc
    11701 catactggcg gccgtttgtg ccagcgatgc cgcctgctgt tcggtacgac ttgagagatc
    11761 gttattgcct gcgacaatct ccgcgatacc aatgtgcatc tcctggcttc ccttacgcac
    11821 atcacttacc gtcccacgca aagcctgctg catggtcttc agactggcaa aaatggcggt
    11881 gatctcatta cgaccatata ccgcaatcgg acgcgccaga ttacccgcag caatgctgtc
    11941 aaaatggcta ccgataatgg ccagtggttg aacaatcatc ttgcgcgtcc accacagcgc
    12001 actgctgatg tagatcgccg caacaataat catgctgata aacaccagtg ccgaaatctg
    12061 atagttacgc tggctttgcg cactggcggc ttccagcaca tggttgatct ccagctgcca
    12121 ggcctcaaag ttaacgtcaa acgcattctg tgatccctgc accggcgcag tgaggaaatc
    12181 cgaaagttga ttactttcaa gccaggtcgc ctgatgttcg agatcgttgt gccagcgggc
    12241 aaaacttttc tccgtctctt tttgcaatcc cctgacgtgc tcgttgcccg cagtcatcgc
    12301 cataaaactt ttaaacagcg tggtggattg cgtcagactg gcgcgcgccg tcgtcatcaa
    12361 cgttttaatg tcatccgccg gatagctaag tgccgtcaga gtgcccgctt tgttcagcgc
    12421 ggtactggcc tgtaacatta ccgcccgagt ttgcgctaat gccgcacgtt gctgattgct
    12481 ctgctcgacc tgattcagtc gttgcaaatc gtcgcgaaat gcccaaaaag acatgccgtt
    12541 actgccaatc tgcaagatcc cgcagagaat caaaattaaa aacagcgtgg tcgaaattcg
    12601 aatacgatta aacatcaacg ctccccatca ggcggcaatg accgcgttag taaatactcg
    12661 tcaaaatgtt tcccagtttg gatcttgttc agcaattcgc agtcgtggct gagccggtgg
    12721 ttgctcactg gcaggacggg atggtgtttg cggtttattg gtgagtgggc tggctgccag
    12781 acggaacgcg gaaactgctt gcgttaaacg actcgcctgt tcttccagcg cagcggcggc
    12841 ggcagctgat tcctgcacca gcgatgcgtt ctgttgcgtg acgcgatcca tttccgaaac
    12901 cgccaatgcg acttgatcga tgccacggct ctgttcatcc gatgccgatg caatctcgcc
    12961 cataatgtca gtcacgcgag tgacagcatt gacgatattg ttcattgttt ccccggcgct
    13021 ttcgaccagc accgaaccgg tatcaacgcg tgagacggag tcttcaatga gggctttgat
    13081 ctcttttgcc gcctgggcgc tgcgactggc aagattacgc acttcacccg ccaccacggc
    13141 aaaaccacgg ccctgttcac ccgcacgcgc ggcttcaacc gcggcattca gcgcgaggat
    13201 attagtctgg aaggcaatac cgtcgataac gctgataatg tcggcaattt tcttcgaact
    13261 atcggcgatc tcatgcatcg ttttcactac gccatccacc actttgccgc cgtgctgggc
    13321 ggtgtcggag gcactttgcg ccagttgcga ggcctggcgg gcgttatcgg cgttttgctt
    13381 cactgtcgcg gtgagctgct ccatgctggc ggcagtttct tccagcgcgg atgcctgctg
    13441 ttcagtacgg gaggaaagat cggtgttgcc cgccgcaatt tcacgggtac cggcatagat
    13501 ggcatctgaa ccttcgcgga catgagtgac ggtgtcagtc aaagagcgtt gcatatgtga
    13561 aacgctctgc gccaggtcgc ccatttcact gcgcccgtca atggtcaggg tattcgccag
    13621 gttaccaccg gcgatttcgc gaatgtgagc aataattttt gccagcggag taagcaacat
    13681 acggcgaatg ccgtaccacg ccaccagcag aatcaatacc accaccagcg cgataaccgc
    13741 cagttgccac tgggcaaatc ggtaatcatc tgcgttgtca gtgacgatat cgcgatacag
    13801 tttttcactg ctgagggcgt actgagcaaa cgcttcgccc attgcatttt gcattccctg
    13861 ggttggctga gcgaaataag ctccagtatt gccataatct agataatcaa tcagttcagt
    13921 taacgctgtg taatagtttt tatatttttc atcaatatta cgactggtag cgaccatttc
    13981 aggtaacggt gccatgcttt tgaatttttt ataatgcgtc gctgcctgcg ccaatgtttt
    14041 cctggcgcta tcgagcaatt caactttggc gttactttgt tgattggagg aatccatcat
    14101 catccgtacc gctgaacgac tcaggttaat gcgcgtttgc agcattaaat cccaggttga
    14161 cgtcagctcg ccctgctgtt cccgtaattg attggaaacc acaaagctct tctggctatg
    14221 gtgaagggaa gaaaaaaaca gactgccgga aataagctgt aacagtgcga atacccccag
    14281 caccattacc aacagcgtga ctacgcggat acggttaatc ataaggcacc ttcctgaaaa
    14341 caagttgatc tcgttatcgg caaggagggg ggaaacttta ttgctgatgc cacccgccgc
    14401 gaaattgaaa taaaaaaccc gatgcgcaga tcatcgggtt catttcaatt gaggaaatcg
    14461 ggagaattac gccacttctg acgccgcgct atctaacagc gccatctctt cgctgttcag
    14521 cagtttttcg atgttcacca gaatcaacat ccggtcgccc agtgcgccca gtccagtgag
    14581 atattctgtt gaaagcgtca cggcaaattc cggtgccgga cgaatttgct ccgccgtcaa
    14641 tgaaagcacg tctgagacgc cgtcaaccac gatgccgacc acccgctgtc cgagattcag
    14701 gacgataact accgtgttgt cgttatagtc cacatccacc tggctgaact taattcgtaa
    14761 gtcaacaatc ggcacaataa cgccgcgcag attcgtgacg cctttgataa acgctggcgt
    14821 gttcgcaatc cgtgttacct gatcgtagcc acggatctcc tgcactttca ggatatcaat
    14881 accgtactct tcatcaccaa gggtaaatac cagaaattcc tggcctgacg gctcgctggc
    14941 cagctttgtt acattcgtca taccggtcat attgttacct ttttactcat tcaggcggcg
    15001 gtgttcgcca tacgttgttc gcggtttatc gcctgcaagg cggagacatc aacaatcagt
    15061 gccacgctgc cgtcgccaag aatggtcgca gcagaaatgc cggggacttt gcgatagtta
    15121 ctttcaaggt ttttaaccac aacctggtgt tgaccaatta attgatccac cagcaaggcg
    15181 tagcggcgac cgccactttg taagatcacc acaattccct gggtggcttc ggttttcgcg
    15241 cccgcgacgt tgaacacttt ccacagttcg acgatgggca gatattcacc ccgcacttcc
    15301 agcacccgct cgccgccggc cagtggatgg agatcggctt cacggggttg cagtgattcc
    15361 ataacagcat tcagcggcag aatgaaaact tcatccgcaa cgcgtacgga catgccgtcg
    15421 aggatggcca gcgtcagcgg cagtaaaatg cggatcgtag tgccagtacc ctgcttcgac
    15481 tggatttcga catgaccgcc catctcctgg atattacgtt taacgacgtc catgccgacg
    15541 ccgcgcccgg agacgtcggt gacctgctct gccgtggaga agccaggtgc aaatatcagc
    15601 atcgcgactt cgtcgtcgct catgttttcg ctgacagtca aaccttgcga ggccgctttt
    15661 gccagaattc gctcacggtt tagccccgcc ccatcgtcgg tcacttcaat gcaaatgttg
    15721 ccgccctgat gttcggcaga cagaattaaa tttccgacgc tgtttttacc tgcggcgagc
    15781 cgtttttctg gcagttcaat accgtgatcg aggctattgc gtaccaggtg ggtcagcggg
    15841 tcgataatgc gttctatcag gcttttgtcg agttcagtag aactgcccac cagcgtcagt
    15901 tctacctgct tgccgagttt tcccgccaga tcacgcacca gccggggata gcgactaaaa
    15961 acatattcca tcggcatcat gcgaatcgac atcactgatt cctgcaaatc atgggcgtta
    16021 cgttgtaact gccccatgct ggttatcaaa tcaccatgat taaccgggtc cagttcgctg
    16081 gaacgctggg caagcatgga ctgggtgata accagctcgc cgacgaggtt aattaattga
    16141 tcaacctttt ctaccgctac acggatgctg gtggattcat tgctgcgcgt cgttttttcc
    16201 cgctccacgc ggccggttgg cgcttgttcg gctgccagtt taagcactgg tggggtggat
    16261 atttttggcg agacttctac tgtttcaaag gtaatctgat cggtttcaat cacaaaacag
    16321 agtaccgctg tgatgtcatc ttcggcgatg tcgcccggta atattgccga gagcgaatcc
    16381 gcccctttca ccacgtcagt taacgttgtc agatgtccca gttcttcttc cagcaggtcg
    16441 acttccccgg ccttcaggcg cgaaaggata attcgtcgcg gcgactgact gcgactctgc
    16501 tcatcttgcg gttcactttt ggcaaccaca cttaatcggg tcactgcgga tggcgtttcg
    16561 cctttcgctt ctaatgccag ttgacgcaag gcctggcaga tataatcgaa gctggcggca
    16621 tccggctctt gcgactgttt ataagcgtcg agctgttctt gcatgatgtc cttcgtttcc
    16681 aaaaacagat tgataatgtc ggtgttgagt tgcatctcac ctcgtctggc ttcatcgagc
    16741 aggttttcca tcagatgcgt ggtttcctgc aaaacgctga agccaaaagt tcctgcccct
    16801 cctttgatcg agtgggcagc ccgaaagatg gcattcaatt gttcggcatc tggcgcttcc
    16861 ggctgcaaaa ccagcaaatg ctgctccatg tcagccaaca gttcgtccgc ttcatcaaaa
    16921 aatgtctgat aaaaatcgct tatatccatg ctcacgctgt cacctcggtt cggctgatgg
    16981 cattgtggga acactgacct gtggtgcaac ctcaggtttt tccagggcgc ttactggctc
    17041 attctggctt tcggcgtttt catgcaaaat ggcctgttcg gcttgtttgt tcagtaccag
    17101 caggctgatg cgacggttga cggcatcatc aggtccgcga tcgcttaagc gcatcgttgc
    17161 cgccatgccg acgacacgta acactttgcc gctatccaac cctccgacca tcagttcgcg
    17221 gcgggatgca ttggcccgat cggcagaaag ctcccagttg ctatatcctt tctcaccgct
    17281 ggcgtagggg aaatcatcgg tatgacctga aaggctaata cggttgggaa taccgttcag
    17341 tacaggcgca atggcgcgca gaatgtcgcg catatagggt tcgacatcgg cactgccggt
    17401 tctaaacatc gggcgattct ggctatcgat gatctgaata cgtagacctt cctggaccag
    17461 atcgattttg agatggggac gtaacgcccg cagtttcgga tcggactcta tcaactggtc
    17521 gagatcaccc cgcaatttcc gcaatcgact ttgctccatg cgttttttca gctcttcgat
    17581 gttcggctgc ttattcactt ccccctggct ttgggtgtaa tcatcaccac cgccgggaat
    17641 tgggctttca ctattagaaa tgcgatcgcc gcccgtaacc gcagtcgcca gtggagtccg
    17701 gaagtactcc gcaatctgaa tcagctcttt tgggctggag atggagatca gccacatcac
    17761 cagaaaaaag gccatcatcg cagtcataaa gtcggcataa gcaatcttcc acgatccatg
    17821 tgctgccccg tggcttttgg ctttgcgtcg tttgacgaca ataatcggat gcgcttgatt
    17881 cttcatgctt cctcggttgt cgtctgttgt tgcggatttt tcaccgcacg cacatgctct
    17941 tccagttcaa taaacgacgg acgttcgctg gaatagagcg ttttgcgacc aaactcaacg
    18001 gcgataggcg gtgcgtaacc gttcagatta gaaagcagag tgactttgac gcactgcatc
    18061 attttgctgg tttcggcgct tttctgacgt aaaacagtcg ctaatgggga aataaatccg
    18121 taagctaata aaatgccgag gaaagtcccc accatcgcat gtgcgataag cgcacccagc
    18181 tcggcggcag gacgatcggc tgaacctaac gcgtgaacga cccccattac agccgcgaca
    18241 ataccaaacg ccggaagtga gtccccgacc agcgccagac tgttcgccgg gacttctgcc
    18301 tcgctttcgt gcgtctcaat ctcttcatcc atcagggctt cgatttcgaa ggtgttcatg
    18361 tgaccgctga taatcaggcg cagataatcg acgataaaat caagcatgac gctatccgcg
    18421 aggatgcgtg gatagctggc gaagatctcg ctctcacggg gattttcaat atcacgttcc
    18481 agcgaaaaca tccccatctg ccgcgatttt gccatcaacc gataaagcag agccagcaga
    18541 tccatataca ttgctttggt gtatttggag cgacgaaaca gcaacggcag cgccttcagc
    18601 gtgcctttaa tcgctttgcc attattgccg acgataaacg acccaatccc tgcaccggca
    18661 ataatcacca gttcagcggg ttgatagagt gctccaaggc ttccaccggt catcaaataa
    18721 ccgccgaaaa ctgtaccgag aacaaccagg taacctaata agataagcac gacatcatcc
    18781 ttccactgtt gaccatgaca ggatgttcag tcgtcaggcg ttaacgcgcg attggggcaa
    18841 aaaaaagcag cggtacgtcg ttaccgctgc tggaatgttg cgcctcaccg tatcagttaa
    18901 acagcctgta ctctctgttc atccagcagt tgtgggataa tatcggcagg attctgggaa
    18961 agtttacgtc tttttactgc ccgggatggc ggttgacata agctgcaggc aaagctgcca
    19021 acaggctggt gagcgtgggt aataaaattg ccgccgcagc agttgcagct ggaaagttgc
    19081 agtaatccac tttcaacaaa ccgcaccaat gtccaggcac gagttaatgc cagcagtggt
    19141 ccttcttctg cttgtgggca ctgttcaagg tataaacggt aggctttgat caccgcatcg
    19201 acgccattac acaaaccggt tttcagtaaa aactgccatg cattacagaa tatcgaagca
    19261 tgaacgtttt gttcccaggt cataaaccag tcggttgaga atggcagcat gcctttcggc
    19321 ggtgggcttc cgcgcagttc tttataaagt tttatcaggc gtccgcgact taactgtgtt
    19381 tcgctttcca gcatctgcaa acgagcgccc agggtgatca attccattgc cagctgaata
    19441 tcccgcgctt cctgaacaat gcttttttca ctcatgatca ggcccttttc ttgcgcagcg
    19501 cttcttcagg ctgattaaca tcattcagca agcgtgttga gagcatgatg ccggtatgaa
    19561 tttgctggag atcgtcaacg cgggaatctt gcgtcaactg agtaatcgtc tggtggctgt
    19621 caaaacggaa gtgacaaacc agctgattgg tttctgccag cttaaccatt tgcggaagag
    19681 tcagtgccgc taatgttgtc gccatttctt catttatgcc gagacgaaac atagcggacg
    19741 ctttgtcctg aacaatcaga cgctgtgcaa gtagtaaata tgacaagttg atgtcataaa
    19801 tgtgtttcag caactcggag gtatgcatta ttcccaccca gaataaccaa ctttattttt
    19861 atgcggtttc accgcaccct gtgatgtcgc cgggaagccc cggtaaaaat aattagcatt
    19921 agaatagttg cgataagctg caataagcag agccaccttt ttggtttaat aagtccttac
    19981 aaatagaagg gggtctttac acttatctaa gatttttcct aaatcgacgc aactgtactt
    20041 gtcactacac gcacatacaa cggagggggg ctgcgatttt caataatgtg tgatgcagat
    20101 cacacaaaac actcaattac tta
//
LOCUS       DAPOAV010000080        19193 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.080, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000080 DAPOAV010000000
VERSION     DAPOAV010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19193
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.080"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            159..235
                     /locus_tag="RN951_003341"
     tRNA            159..235
                     /locus_tag="RN951_003341"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:193..195,aa:Arg,seq:acg)
     gene            516..1082
                     /gene="yqaB"
                     /locus_tag="RN951_003342"
     CDS             516..1082
                     /gene="yqaB"
                     /locus_tag="RN951_003342"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1-phosphate/6-phosphogluconate
                     phosphatase"
                     /protein_id="HDX2528296.1"
                     /translation="MYERYAGLIFDMDGTILDTEPTHRKAWREVLGHYGLQYDVQAMI
                     ALNGSPTWRIAQAIIELNQADLDPHALAREKTEAVRSMLLDSVEPLPLVEVVKSWHGR
                     RPMAVGTGSESAIAEALLAHLGLRRYFDAVVAADHVKHHKPAPDTFLLCAQRIGVQPT
                     QCVVFEDADFGIQAARAAGMDAVDVRLL"
     gene            1079..1507
                     /locus_tag="RN951_003343"
     CDS             1079..1507
                     /locus_tag="RN951_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDX2528297.1"
                     /translation="MSEALSLFSLFASSFLSATLLPGNSEVVLVAMLLSGISYPWVLV
                     LTATMGNSLGGLTNVILGRFFPLRKTSRWQEKATGWLKRYGAVTLLLSWMPVVGDLLC
                     LLAGWMRISWGPVIFFLCLGKALRYVAVAAATVQGMMWWH"
     gene            1580..3136
                     /gene="gshA"
                     /locus_tag="RN951_003344"
     CDS             1580..3136
                     /gene="gshA"
                     /locus_tag="RN951_003344"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HDX2528298.1"
                     /translation="MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGH
                     PEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPL
                     SMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFW
                     QAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPF
                     EKTECGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAK
                     IGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDI
                     NPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLG
                     IGCETAQFPLLQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSAR
                     ILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMETADTE
                     PFAVWLEKHA"
     gene            3286..3801
                     /gene="luxS"
                     /locus_tag="RN951_003345"
     CDS             3286..3801
                     /gene="luxS"
                     /locus_tag="RN951_003345"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008458247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HDX2528299.1"
                     /translation="MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPN
                     KEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVAD
                     AWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELA
                     LPEEKLQELHI"
     gene            complement(3865..5403)
                     /gene="emrB"
                     /locus_tag="RN951_003346"
     CDS             complement(3865..5403)
                     /gene="emrB"
                     /locus_tag="RN951_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrB"
                     /protein_id="HDX2528300.1"
                     /translation="MQQQKPLEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNL
                     GSSLSQGTWVITSFGVANAISIPLTGWLAKRVGEVKLFLWSTIAFAIASWACGVSSSL
                     NMLIFFRVIQGIVAGPLIPLSQSLLLNNYPPAKRSIALALWSMTVIVAPICGPILGGY
                     ISDNYHWGWIFFINVPIGVAVVLMTLQTLRGRETRTERRRIDAVGLALLVIGIGSLQI
                     MLDRGKELDWFSSQEIIILTVVAVVAICFLIVWELTDDNPIVDLSLFKSRNFTIGCLC
                     ISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGIIPVILSPIIGRFAHKLDMR
                     RLVTFSFIMYAVCFYWRAYTFEPGMDFGASAWPQFIQGFAVACFFMPLTTITLSGLPP
                     ERLAAASSLSNFTRTLAGSIGTSITTTMWTNRESMHHAQLTESVNPFNPNAQAMYSQL
                     EGLGMTQQQASGWIAQQITNQGLIISANEIFWMSAGIFLVLLGLVWFAKPPFGAGGGG
                     GGAH"
     gene            complement(5420..6592)
                     /gene="emrA"
                     /locus_tag="RN951_003347"
     CDS             complement(5420..6592)
                     /gene="emrA"
                     /locus_tag="RN951_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter periplasmic
                     adaptor subunit EmrA"
                     /protein_id="HDX2528301.1"
                     /translation="MSANAETQTPQQPVKKSGKRKRLLLLLTLLFIIIAVAIGIYWFL
                     VLRHFEETDDAYVAGNQIQIMSQVSGSVTKVWADNTDFVKEGDVLVTLDPTDARQAFE
                     KAKTALASSVRQTHQLMINSKQLQANIEVQKIALAKAQSDYNRRVPLGNANLIGREEL
                     QHARDAVTSAQAQLDVAIQQYNANQAMILGTKLEDQPAVQQAATEVRNAWLALERTRI
                     VSPMTGYVSRRAVQPGAQISPTTPLMAVVPATNMWVDANFKETQIANMRIGQPVTITT
                     DIYGDDVKYTGKVVGLDMGTGSAFSLLPAQNATGNWIKVVQRLPVRIELDQKQLEQYP
                     LRIGLSTLVSVNTTNRDGQVLANKVRSTPVAVSTAREISLAPVNKLIDDIVKANAG"
     gene            complement(6719..7249)
                     /gene="emrR"
                     /locus_tag="RN951_003348"
     CDS             complement(6719..7249)
                     /gene="emrR"
                     /locus_tag="RN951_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter EmrAB
                     transcriptional repressor EmrR"
                     /protein_id="HDX2528302.1"
                     /translation="MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQSKLLENR
                     NKMLKAQGINETLFMALITLESQENHSIQPSELSCALGSSRTNATRIADELEKRGWIE
                     RRESDNDRRCLHLQLTEKGHEFLREVLPPQHNCLHQLWSALSTTEKDQLEQITRKLLS
                     RLDQMEQDGVVLEAMS"
     gene            complement(7340..7675)
                     /gene="ygaH"
                     /locus_tag="RN951_003349"
     CDS             complement(7340..7675)
                     /gene="ygaH"
                     /locus_tag="RN951_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-valine transporter subunit YgaH"
                     /protein_id="HDX2528303.1"
                     /translation="MSYEVLLLGLLVGVANYCFRYLPLRLRVGNARPTKRGAVGILLD
                     TIGIASICALLVVSTAPEVMHDTRRFVPTLVGFAVLGDSFYKTRSIIIPTLLSALAYG
                     LAWKVMAII"
     gene            complement(7665..8402)
                     /gene="ygaZ"
                     /locus_tag="RN951_003350"
     CDS             complement(7665..8402)
                     /gene="ygaZ"
                     /locus_tag="RN951_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-valine exporter subunit YgaZ"
                     /protein_id="HDX2528304.1"
                     /translation="MESPTPQPAPGSATFMEGCKDSLPIVISYIPVAFAFGLNATRLG
                     FSPLESVFFSCIIYAGASQFVITAMLAAGSSLWVAALTVMAMDVRHVLYGPSLRSRII
                     QRLQKSKTALWAFGLTDEVFAAATAKLVRNNRRWSENWMIGIAFSSWSSWVFGTVIGA
                     FSGSGLLQGYPAVEAALGFMLPALFMSFLLASFQRKQSLCVTAALVGALAGVTLFSIP
                     VAILAGIVCGCLTALIQAFWQGAPDEL"
     gene            complement(8526..9710)
                     /locus_tag="RN951_003351"
     CDS             complement(8526..9710)
                     /locus_tag="RN951_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2528305.1"
                     /translation="MTKPNHELSPALIVLMSIATGLAVASNYYAQPLLDTIARNFSLS
                     ASSAGFIVTAAQLGYAAGLLFLVPLGDMFERRRLIVSMTLLAAGGMLITASSQSLAMM
                     LLGTALTGLFSVVAQILVPLAATLASPDKRGKVVGTIMSGLLLGILLARTVAGLLANL
                     GGWRTVFWVASVLMALMALALWRGLPQMKSETHLNYPQLLGSVFSMFINDKILRTRAL
                     LGCLTFANFSILWTSMAFLLAAPPFNYSDGVIGLFGLAGAAGALGARPAGGFADKGKS
                     HHTTTFGLLLLLLSWLAIWFGHTSVLALIIGILVLDLTVQGVHITNQTVIYRIHPDAR
                     NRLTAGYMTSYFIGGAAGSLISASAWQHGGWAGVCLAGATIALVNLLVWWRGFHRQEA
                     AN"
     gene            complement(9902..10894)
                     /gene="proX"
                     /locus_tag="RN951_003352"
     CDS             complement(9902..10894)
                     /gene="proX"
                     /locus_tag="RN951_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     substrate-binding protein ProX"
                     /protein_id="HDX2528306.1"
                     /translation="MRHSVLFATAFATLISTQTFAADLPGKGITVNPVQSTITEETFQ
                     TLLVSRALEKLGYTVNKPSEVDYNVGYTSLASGDATFTAVNWTPLHDNMYEAAGGDKK
                     FYREGVFVNGAAQGYLIDKKTADQYKITNIAQLKDPKIAKLFDTNGDGKADLTGCNPG
                     WGCEGAINHQLAAYELTHTVTHNQGNYAAMMADTISRYKEGKPVFYYTWTPYWVSNEL
                     KPGKDVVWLQVPFSALPGDKNADTKLPNGANYGFPVSTMHIVANKAWAEKNPAAAKLF
                     AIMQLPVADINAQNAIMHDGKASEGDIQGHVDGWIKAHQQQFDGWVNEALAAQK"
     gene            complement(10952..12016)
                     /gene="proW"
                     /locus_tag="RN951_003353"
     CDS             complement(10952..12016)
                     /gene="proW"
                     /locus_tag="RN951_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     permease ProW"
                     /protein_id="HDX2528307.1"
                     /translation="MADQNNPWDTTPAADSAVQSADAWGTPATAPTDGGGADWLTSTP
                     APNVEHFNILDPFHKTLIPLDSWVTEGIDWVVTHFRPVFQGVRVPVDYILNGFQQLLL
                     GMPAPVAIIVFALIAWQISGVGMGVATLVSLIAIGAIGAWSQAMVTLALVLTALLFCI
                     VIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFA
                     LPPIIRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLAL
                     SMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAIILDRLTQAVGRDSRSR
                     GNRRWYTTGPVGLLTRPFIK"
     gene            complement(12009..13211)
                     /gene="proV"
                     /locus_tag="RN951_003354"
     CDS             complement(12009..13211)
                     /gene="proV"
                     /locus_tag="RN951_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein ProV"
                     /protein_id="HDX2528308.1"
                     /translation="MAIKLEIKNLYKIFGEHPQRAFKYIEQGLSKEQILEKTGLSLGV
                     KDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELRE
                     VRRKKIAMVFQSFALMPHMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHS
                     YPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDELVKLQAKHQRTI
                     VFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFFRGVDISQVFSA
                     KDIARRTPNGLIRKTPGFGPRSALKLLQDEDREYGYVIERGNKFVGAVSIDSLKTALT
                     QQQGLDAALIDAPLAVDAQTPLSELLSHVGQAPCAVPVVDEDQQYVGIISKGMLLRAL
                     DREGGNNG"
     gene            complement(13566..14525)
                     /gene="nrdF"
                     /locus_tag="RN951_003355"
     CDS             complement(13566..14525)
                     /gene="nrdF"
                     /locus_tag="RN951_003355"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HDX2528309.1"
                     /translation="MKLSRISAINWNKISDDKDLEVWNRLTSNFWLPEKVPLSNDIPA
                     WQTLSVVEQQLTMRVFTGLTLLDTLQNVIGAPSLMPDALTPHEEAVLSNISFMEAVHA
                     RSYSSIFSTLCQTKDVDAAYAWSEENAPLQRKAQIIQQHYRGDDPLKKKIASVFLESF
                     LFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQKNMEKISLGQREEL
                     KSFAFDLLLELYDNELQYTDELYAETPWADDVKAFLCYNANKALMNLGYEPLFPAEMA
                     EVNPAILAALSPNADENHDFFSGSGSSYVMGKAVETEDEDWNF"
     gene            complement(14535..16679)
                     /gene="nrdE"
                     /locus_tag="RN951_003356"
     CDS             complement(14535..16679)
                     /gene="nrdE"
                     /locus_tag="RN951_003356"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HDX2528310.1"
                     /translation="MATTTAECLTQETMDYHALNAMLNLYDSAGRIQFDKDRQAVDAF
                     IATHVRPNSVTFSSQQQRLNWLVNEGYYDESVLNRYSRDFVITLFAHAHTSGFRFQTF
                     LGAWKFYTSYTLKTFDGKRYLEDFADRVTMVALTLAQGDATLALQLTDEMLSGRFQPA
                     TPTFLNCGKQQRGELVSCFLLRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAG
                     APIKRIENQSSGVIPVMKMLEDAFSYANQLGARQGAGAVYLHAHHPDILRFLDTKREN
                     ADEKIRIKTLSLGVVIPDITFHLAKENAQMALFSPYDVERVYGKPFADIAISEHYDEL
                     VADERIRKKYLNARDFFQRLAEIQFESGYPYIMYEDTVNRANPIAGRINMSNLCSEIL
                     QVNSASEYDENLDYARTGHDISCNLGSLNIAHTMDSPNFARTVETAVRGLTAVSDMSH
                     IRSVPSIEAGNAASHAIGLGQMNLHGYLAREGIAYGSPEALDFTNLYFYTITWHALRT
                     SMLLARERGETFAGFKQSRYASGEYFSQYLQGNWQPKTAKVGELFARSGITLPTREMW
                     AQLRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKVEIRKEGKTGRVYYPA
                     PFMTNENLALYQDAYEIGAEKIIDTYAEATRHVDQGLSLTLFFPDTATTRDINKAQIY
                     AWRKGIKTLYYIRLRQMALEGTEIEGCVSCAL"
     gene            complement(16652..17062)
                     /gene="nrdI"
                     /locus_tag="RN951_003357"
     CDS             complement(16652..17062)
                     /gene="nrdI"
                     /locus_tag="RN951_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HDX2528311.1"
                     /translation="MSQLVYFSSSSENTQRFIERLGLPAVRIPLNERERIQVDEPYIL
                     IVPSYGGGGTAGAVPRQVIRFLNDEHNRALLRSVIASGNRNFGEAYGRAGDVIARKCG
                     VPWLYRFELMGTQSDIENVRKGVTEFWQRQPQNA"
     gene            complement(17059..17304)
                     /gene="nrdH"
                     /locus_tag="RN951_003358"
     CDS             complement(17059..17304)
                     /gene="nrdH"
                     /locus_tag="RN951_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HDX2528312.1"
                     /translation="MRITIYTRNDCVQCHATKRAMENRGFDFEMINVDRVPEAAEALR
                     AQGFRQLPVVIAGDLSWSGFRPDMINRLHPAPHAASA"
     gene            complement(17552..17881)
                     /locus_tag="RN951_003359"
     CDS             complement(17552..17881)
                     /locus_tag="RN951_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311560.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 domain-containing protein"
                     /protein_id="HDX2528313.1"
                     /translation="MFNRPNRNDVDDGVQDIQNDVNQLADSLESVLKSWGSDAKGEAE
                     AARSKAQALLKETRARMHGRTRVQQAARDAVGCADSFVRERPWCSVGTAAAVGIFIGA
                     LLSMRKS"
     gene            18033..18377
                     /locus_tag="RN951_003360"
     CDS             18033..18377
                     /locus_tag="RN951_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgaC family protein"
                     /protein_id="HDX2528314.1"
                     /translation="MYLRPDEVARVLEKVGFTVDVVTQKAYGYRRGENYVYVNREARM
                     GRTALVIHPTLKERSSTLAEPASDIKTCDHYQQFPLYLAGERHEHYGIPHGFSSRVAL
                     ERYLNGLFGETS"
     gene            complement(18414..18863)
                     /gene="alaE"
                     /locus_tag="RN951_003361"
     CDS             complement(18414..18863)
                     /gene="alaE"
                     /locus_tag="RN951_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-alanine exporter AlaE"
                     /protein_id="HDX2528315.1"
                     /translation="MFSPQSRLRHAVADTFAMVVYCSVVNMCIEVFLSGMSFEQSFYS
                     RLVAIPVNILIAWPYGMYRDLFMRAARKVSPSGWIKNLADILAYVTFQSPVYVAILLV
                     VGADWHQIMAAVSSNIVVSMLMGAVYGYFLDYCRRLFKVSRYQQVKA"
BASE COUNT         4817 a         4853 c         4959 g         4564 t
ORIGIN      
        1 agcggaatta accgcaggca ccagggatga taacgttgct ttagcaacgg cccgaagggc
       61 gagccgcaag gcgagtaatc ctcccggatg caccatctct tacttgatat ggctttagta
      121 gcgatatcaa tatcagcagt aaaataaatt ttcccgatgc atccgtagct cagctggata
      181 gagtactcgg ctacgaaccg agcggtcgga ggttcgaatc ctcccggatg caccatattc
      241 tccgtaacct tcagcaatga aggtatcgaa gagatagcgg tattaaccgc aggcaccagg
      301 gaggataacg ttgcgtcagc aacggcccga agggcgaacg ccagtgagta atcctcccgg
      361 atgcaccatc ttctcccaaa aatttccttc aaaaatatct catttctaaa taactacttt
      421 atccatttcc tgaattttct tctccttcgc catcagcgac aaaatcaagc aattacgcta
      481 aagtagcgtc atatttttcg acttgcgaga agaccatgta cgagcgttat gcaggtttaa
      541 tttttgatat ggatggcaca atcctggata cggagcctac gcaccgtaaa gcgtggcgcg
      601 aagtattagg gcactacggt cttcagtacg atgttcaggc aatgattgcg cttaatggat
      661 cgcccacctg gcgtattgct caggcaatta ttgagctgaa tcaggccgat ctcgacccgc
      721 atgcgttagc gcgtgaaaaa acagaagcag taagaagtat gctgctggat agtgtcgagc
      781 cgcttcctct tgttgaagtg gtgaaaagtt ggcatggtcg tcgcccaatg gctgtaggaa
      841 cggggagtga aagcgccatc gctgaggcat tgctggcgca cctgggatta cgccgttatt
      901 ttgacgccgt cgtcgctgct gatcacgtca aacaccataa acccgcgcca gacacatttt
      961 tgttgtgcgc gcagcgtatt ggcgtgcaac cgacgcagtg tgtggtcttt gaagatgccg
     1021 atttcggtat tcaggcggcc cgtgcagcag gcatggacgc cgtggatgtt cgcttgctgt
     1081 gagtgaagcg ttatcgcttt tctcgttgtt tgccagtagt tttctcagcg ctacactatt
     1141 acccggcaac tccgaagtcg tgctggtggc aatgttgctt tccgggatca gttatccctg
     1201 ggttttagtt ttaacagcaa caatgggtaa tagccttgga gggttaacta acgttatcct
     1261 tgggcgtttc tttccattgc gtaaaacatc gcgctggcaa gagaaagcta ccggctggct
     1321 gaaacgctat ggtgcagtca cgctattatt aagctggatg cccgtggttg gcgatttact
     1381 gtgtctgtta gcgggatgga tgcgcatctc ctgggggcca gtaatctttt ttttgtgcct
     1441 tggtaaagcg ttacgctatg ttgcagttgc agcagcgacc gttcagggca tgatgtggtg
     1501 gcactaattg taggcctgca catatggtca ccattacagt tatgctaatt aaaacgattt
     1561 tgacaggcgg gaggtcaatt tgatcccgga cgtatcacag gcgctggcct ggctggaaaa
     1621 acatcctcag gcgttaaagg ggatacagcg tgggctggag cgcgaaactt tgcgtgttaa
     1681 tgctgatggc acactggcaa caacaggtca tcctgaagca ttaggttccg cactgacgca
     1741 caaatggatt actaccgatt ttgcggaagc attgctggaa ttcattacac cagtggatgg
     1801 tgatattgaa catatgctga cctttatgcg cgatctgcat cgttatacgg cgcgcaatat
     1861 gggtgatgag cggatgtggc cgttaagtat gccatgctac atcgcagaag gtcaggacat
     1921 cgaactggca cagtacggca cttctaacac cggacgcttt aaaacgctgt atcgtgaagg
     1981 gctgaaaaat cgctacggcg cgctgatgca aaccatttcc ggcgtgcact acaatttctc
     2041 tttgccaatg gcattctggc aagcgaagtg cggtgatatc tcgggcgctg atgccaaaga
     2101 gaaaatttct gcgggctatt tccgcgttat ccgcaattac tatcgtttcg gttgggtcat
     2161 tccttatctg tttggtgcat ctccggcgat ttgttcttct ttcctgcaag gaaaaccaac
     2221 gtcgctgccg tttgagaaaa ccgagtgcgg tatgtattac ctgccgtatg cgacctctct
     2281 tcgtttgagc gatctcggct ataccaataa atcgcaaagc aatcttggta ttaccttcaa
     2341 cgatctttac gagtacgtag cgggccttaa acaggcaatc aaaacgccat cggaagagta
     2401 cgcgaagatt ggtattgaga aagacggtaa gaggctgcaa atcaatagca acgtgctgca
     2461 gattgaaaac gaactgtatg cgccgattcg tccaaaacgc gttacccgca gcggcgagtc
     2521 accttctgat gcgctgttac gtggcggcat tgaatatatt gaagtgcgtt cgctggacat
     2581 caacccgttc tcgccgattg gtgtagatga acagcaggtg cgattcctcg acctgtttat
     2641 ggtctggtgt gcgctggctg atgcaccgga aatgagcagt agcgaacttg cctgtacgcg
     2701 cgttaactgg aaccgggtga tccttgaagg tcgcaaaccg ggcctgacgc tgggtatcgg
     2761 ctgcgaaacc gcgcagttcc cgttactgca ggtgggtaaa gatctgttcc gcgatctgaa
     2821 acgcgtcgcg caaacgctgg atagcattaa cggcggcgaa gcgtatcaga aagtgtgtga
     2881 tgaactggtt gcctgcttcg ataatcccga tctgactttc tctgcccgta tcttaaggtc
     2941 tatgattgat actggtattg gcggaacagg caaagcgttt gcagaagcct accgtaatct
     3001 gctgcgtgaa gagccgctgg aaattctgcg cgaagaggat tttgtagccg agcgcgaggc
     3061 atctgaacgc cgtcagcagg aaatggaaac cgctgatacc gaaccgtttg cggtgtggct
     3121 ggaaaaacac gcctgacaga aaagaaaaag gccactcgtg agtggccaaa atttcatctc
     3181 tgaattcagg gatgatgata acaaatgcgc gtctttcata tactcagact cgcctgggaa
     3241 gaaagagttc agaaaatttt aaaaaaaatt accggaggtg gctaaatgcc gttgttagat
     3301 agcttcacag tcgatcatac ccggatggaa gcgcctgcag ttcgggtggc gaaaacaatg
     3361 aacaccccgc atggcgacgc aatcaccgtg ttcgatctgc gcttctgcgt gccgaacaaa
     3421 gaagtgatgc cagaaagagg gatccatacc ctggagcacc tgtttgctgg ttttatgcgt
     3481 aaccatctta acggtaatgg tgtagagatt atcgatatct cgccaatggg ctgccgcacc
     3541 ggtttttata tgagtctgat tggtacgcca gatgagcagc gtgttgctga tgcctggaaa
     3601 gcggcaatgg aagacgtgct gaaagtgcag gatcagaatc agatcccgga actgaacgtc
     3661 taccagtgtg gcacttacca gatgcactcg ttgcaggaag cgcaggatat tgcgcgtagc
     3721 attctggaac gtgacgtgcg catcaacagc aacgaagaac tggcgctgcc ggaagagaag
     3781 ttgcaggaac tgcacattta gtcagtaaac tatcttcaca attaattgaa aaaagccagt
     3841 tcaaatgaac tggcttagtt gtacttagtg cgcaccgcct ccgccgccac ctgcgccaaa
     3901 tggcggttta gcaaaccaca ccagccccag caggacgagg aatatcccgg ctgacatcca
     3961 gaagatctca ttggcggaaa taatcagccc ctgattggtg atctgctggg caatccagcc
     4021 tgatgcctgc tgttgcgtca tcccaagccc ttccagttga ctgtacatcg cctgggcatt
     4081 cgggttgaac gggtttaccg actcagtcaa ctgcgcatgg tgcatcgact cgcggttggt
     4141 ccacatggtc gtggttatcg acgtgccgat agaccccgcc agcgttcgcg taaagttaga
     4201 gaggctcgat gccgccgcca gtcgttccgg tggcaaacca gacagcgtaa tggtggtcag
     4261 cggcataaag aagcaggcca ccgcaaaccc ctggataaac tgcggccagg ccgacgcgcc
     4321 aaaatccata cctggttcaa aggtataggc acgccagtag aagcagacgg catacataat
     4381 aaagctgaag gttaccagcc gccgcatatc cagtttatgc gcgaagcggc cgataatcgg
     4441 cgacaggatc accggaataa tccctaccgg cgcagaggcc aaacctgccc aggtcgccgt
     4501 gtaaccgtag acctcctgca acaactgcgg cagcagaaca atagcgccga agtagagcat
     4561 atacgcgagg ctgatacaca agcagccgat ggtgaagttg cgcgacttaa acaacgacag
     4621 atcgactatc gggttatcgt cggtcagctc ccagacaatc aggaagcaga tagccaccac
     4681 cgccaccacg gtaagaatga taatttcctg tgatgagaac cagtccagct ctttaccgcg
     4741 gtcgagcata atctgcaggc tgccgatacc aataaccagc agtgccagcc ccacggcatc
     4801 aatccgccgc cgttcggtgc gggtttcacg tccgcgcaga gtttgcagtg tcatcaacac
     4861 caccgccacg ccaatcggca cgttgatgaa gaatatccag ccccagtggt aattatcgct
     4921 gatataaccg ccgaggatcg ggccgcaaat tggcgcgaca atcaccgtca tcgaccacaa
     4981 cgccagcgcg atcgagcgtt tggctggcgg gtagttattc agcaatagac tttgcgaaag
     5041 cgggatcaac ggcccggcga caatcccctg aatcacgcgg aagaagatca gcatattcag
     5101 gctgctggag acaccacacg cccacgacgc aatagcaaag gcgatggtgg accaaaggaa
     5161 cagtttcact tccccgacgc gctttgccag ccagccggta agcgggatcg agatggcatt
     5221 cgccaccccg aaagaagtga ttacccacgt tccctggctg agcgatgagc ccagattccc
     5281 ggcgatagtg gggatcgcca cgttagcaat ggtggagtcc agcacctgca tgaatgtcgc
     5341 cagtgacagc gcaatcgtca taatgaccag ttgcgcgcct tccagcggtt tttgctgttg
     5401 catcacacgc acctctggat tagccagcgt tagcttttac gatatcgtcg atcagtttat
     5461 tgacaggtgc caggctgatt tcacgcgcgg tacttaccgc gaccggtgtt gaacgtactt
     5521 tatttgccag tacctgaccg tcacggttag tggtattgac gctcaccagc gtggacaaac
     5581 caatgcgcag cgggtattgc tccagctgtt tctggtccag ttcgatacgc acaggtagac
     5641 gctgaacgac tttgatccag ttaccggtcg cattttgcgc cggaagcagt gagaatgcgc
     5701 tacctgtgcc catatccaga ccaaccactt taccggtgta tttcacatca tcgccgtaaa
     5761 tatccgtggt gatagtgacc ggctgaccga tacgcatatt ggcaatctgc gtctctttaa
     5821 agttggcatc cacccacata ttggtggctg gaacgaccgc catcagcggc gtcgttgggc
     5881 taatttgcgc cccaggctgt accgcgcggc gggagacata accggtcatc ggactgacaa
     5941 tacgggtacg ctccagcgcc agccaggcgt tacgtacttc ggtggcagcc tgttgcacgg
     6001 caggctgatc ttccagttta gtccccagaa tcatcgcctg attggcattg tattgttgaa
     6061 tagcgacgtc cagttgcgcc tgggcactgg tgacggcgtc gcgggcgtgt tgcagctctt
     6121 cgcgaccaat caggttggca ttgcccagcg gcacacggcg gttgtagtcg ctttgtgctt
     6181 tcgcgagggc gattttttgc acctcaatat tcgcctgcaa ctgtttgctg ttaatcatca
     6241 gctggtgggt ttggcgaacg ctggaagcca gtgcagtttt ggctttttca aacgcctggc
     6301 gagcatctgt cgggtcgaga gtgaccagaa catcgccttc ttttacaaaa tcggtgttat
     6361 cggcccagac tttcgtcacg ctgccagaca cctgagacat aatttgaatc tgattccctg
     6421 ccacgtatgc gtcatcggtt tcttcgaaat gacgcagtac caaaaaccaa taaatcccta
     6481 tcgctacggc aataattata aagagcaagg tgagaaggag gagcagacgc ttacgtttgc
     6541 cgctcttctt taccggttgc tgcggggttt gagtctccgc atttgcgctc atattgttct
     6601 ccacgatctt cttaactcat cggctgagcc gacctgcttg ccaaaaaggc cagcatgttg
     6661 cgatgctggc cggtcatttt ttcttttata aatctggatt tttgagcgag atgacgcgtt
     6721 agctcatcgc ttcgagaacc acaccgtctt gttccatctg gtcgagacgg gagagcaatt
     6781 tgcgggtgat ttgctcgagc tgatcttttt ctgttgtgct gagcgcggac cagagttgat
     6841 gcaggcagtt atgctgcggt ggtaaaacct cgcgcaaaaa ctcgtgacct ttttccgtta
     6901 attgcagatg caggcagcgg cgatcgttat cgctttcacg acgttcgatc caaccgcgtt
     6961 tttccagttc atcggcaata cgcgtcgcgt tggtacggga tgatccaaga gcacaactta
     7021 attcagaagg ctgaatactg tggttttcct gagactccag cgtaatcaac gccataaaca
     7081 acgtctcgtt aatcccctga gccttcagca ttttattgcg gttctccagc agcttgcttt
     7141 gcatgtgcat gcaaagacga gtcagaagga tctcctgata aggaaaatct tcgtggcggc
     7201 tggcgcgaaa ttttagcatt tgttcaatgg gcgtaaacga actatccatt tgggtatgac
     7261 ctcattaatt tcagccgata tagtaacgac agtgacaaat aaagtaaatg tattgtttta
     7321 gaaaaatgat tcttgtgggt tatataatcg ccatcacttt ccaggcgagc ccataggcca
     7381 gcgcactaag cagtgttggg atgataatgc tgcgtgtttt atagaaactg tcacccagta
     7441 ccgcgaagcc gaccagcgtg ggcacgaaac ggcgtgtatc gtgcatcact tctggtgcgg
     7501 tagagacaac cagcagagcg catatcgagg cgatgccaat ggtgtcgagc aaaataccta
     7561 ccgcgccacg tttggttggg cgggcattac ccacacgcag gcgcagcggc aaatagcgga
     7621 agcaataatt cgccacgcca accagtaacc caagcagcag aacctcatag ctcatcgggc
     7681 gctccttgcc agaatgcctg gattaacgca gtgaggcagc cacagacaat gcctgccaga
     7741 atggcgacgg gaatagaaaa tagcgttacg cctgcaaggg caccaactaa cgctgcggta
     7801 acgcaaagag attgtttgcg ctggaaagag gcgagcagga aactcataaa gagtgccgga
     7861 agcataaaac ctaatgcagc ttcaacggcg ggataacctt gcagcaagcc gctgccggag
     7921 aatgccccta ttaccgtacc aaatacccac gatgaccatg aactgaaggc aatgccgatc
     7981 atccagttct cgctccagcg gcgattattg cgtaccagtt ttgcggttgc ggcggcaaaa
     8041 acctcatccg tcaggccaaa tgcccacagg gcggttttcg atttttgcag acgctgaata
     8101 atacggctac gcagtgacgg gccatacaac acatggcgaa catccattgc catgacggtc
     8161 agtgcagcaa cccacaaact actcccggct gccagcatcg cggtaatgac gaactggctc
     8221 gcgcctgcat aaatgatgca ggagaaaaaa acgctttcga gaggagagaa tcccagacgg
     8281 gtcgcattca gaccgaacgc aaaggccacc ggaatataac taataacaat cggtaaactg
     8341 tctttgcatc cttccatgaa ggtcgccgaa ccaggagcag gctgtggagt agggctttcc
     8401 atagagtgta cgcttaacga ttgttaatat tataaataga ctgaatgaat atcttaacct
     8461 tatcagactg atgggcttct taacaccctt ataagtgtaa agccacgaaa acggttgctg
     8521 attgcttaat ttgcggcttc ctgacgatga aaacctcgcc accagaccag taagttaacc
     8581 agggcaatcg tcgcgccagc cagacaaacg ccagcccaac cgccatgttg ccaggctgag
     8641 gctgaaatta gcgaaccggc ggcaccgcca ataaagtagc tggtcatgta acctgcggtc
     8701 aggcgattac gcgcatcagg gtgtattcga taaattaccg tctggttagt gatatgcacg
     8761 ccctgtacgg tgagatccag caccaggatt ccgataatca acgccagtac ggaagtgtga
     8821 ccaaaccaga tcgccagcca tgaaagtaat agcagcagca gaccgaaagt tgtggtgtgg
     8881 tgcgatttac ccttatcggc aaaaccgccc gccggacgag cgcccaacgc gccggcagct
     8941 cccgcaagtc caaacagacc aatgacacca tcgctgtagt taaaaggtgg agcggcaagc
     9001 aaaaaggcca ttgaggtcca gagaatgctg aagttggcaa aggtcaggca gccaagcaat
     9061 gcgcgggtgc gcaggatctt atcgttgata aacatgctga aaacggaacc caacaactgt
     9121 gggtagttga ggtgggtttc tgatttcatt tgtggcagac cacgccataa tgctagcgcc
     9181 atcagagcca ttaacaccga ggcaacccaa aagacggtgc gccagccgcc gaggtttgcc
     9241 agtaacccgg caacggttcg tgccagcaat atccccaaca gcagaccgct cataatggtg
     9301 ccaaccactt tgccgcgttt atccggtgaa gccagcgtcg ctgccagcgg aaccagaatt
     9361 tgtgccacga cagagaataa accggttaat gccgtaccga ggagcatcat cgccagcgac
     9421 tgactgctgg cggtaatcaa cataccgccc gctgccagta aggtcatcga gacaatcagg
     9481 cggcggcgtt caaacatatc accgagggga acaagaaaca gcagacctgc tgcatagccc
     9541 aattgcgcgg cggtaacaat aaagcctgcc gaactggcgg aaagggaaaa gttacgcgcg
     9601 atggtgtcga gtagcggctg ggcgtaatag ttactggcga ccgccagacc ggtggcgata
     9661 gacatcagca cgatcagcgc cgggctaagc tcatgattag gtttagtcat tatttttgtt
     9721 catcaggtga tgattaagct ggaaatcaat aatagcggat gttgatgaat atgggatgaa
     9781 agatagcttg ttgaaatgtg cgatgtggtt tgtaggcatg ataagacgcg tcagcgtcgc
     9841 atcaggcatt gtgtacagag cggcggatga ggcaaaaacg ccttatccgc ccgaataaaa
     9901 attacttctg cgctgccagc gcctcattca cccagccatc gaactgctgc tggtgggctt
     9961 tgatccagcc atcaacatgg ccctgaatat cgccttctga ggctttgccg tcatgcataa
    10021 tggcgttctg ggcgttaata tctgccactg gcaactgcat aatggcaaac agtttcgctg
    10081 ctgccgggtt tttctcggcc caggctttgt tggcaacgat atgcatggtg ctgaccggga
    10141 agccataatt cgcaccattc ggcagtttgg tatcggcgtt tttatcgccc ggcagtgcgg
    10201 agaacggcac ctgcaaccag accacatctt tccctggctt cagctcatta ctcacccagt
    10261 acggcgtcca ggtataataa aacaccggtt tgccctcttt gtagcgactg atggtgtcgg
    10321 ccatcatcgc cgcgtagttc ccctgattat gcgtcacggt atgggtcagt tcatacgcgg
    10381 caagctggtg gttgatggca ccttcgcagc cccagccagg gttacacccg gttaaatccg
    10441 ctttaccgtc gccgttggta tcgaacagtt tggcgatctt cggatctttc agttgtgcga
    10501 tgttggtgat tttatactgg tcggcggttt tcttatcgat caggtaaccc tgtgccgcgc
    10561 cgttaacaaa taccccttca cgataaaatt tcttatcgcc accggcagct tcgtacatgt
    10621 tgtcatgcag tggcgtccag ttcacggcgg tgaaggttgc atcgccggaa gcaagcgagg
    10681 tgtagccaac gttgtaatct acttcgctgg gtttgttgac ggtatagcct aatttctcca
    10741 gcgcacggct gaccagcagc gtctggaagg tttcttcggt gatggtgctt tgaactggat
    10801 taacagtaat acctttgccc ggcagatcgg cagcaaaagt ttgtgtagag ataagcgtgg
    10861 caaacgctgt cgcaaaaagt acgctatgtc gcattgttat tccttttttt ggcagggtga
    10921 taatgcccgg cgtcaccggg caagtgcaga gttacttaat gaatgggcgg gtcagcagac
    10981 caacagggcc agtggtgtac cagcgacggt tgccgcgact gcgtgagtcg cgcccaacgg
    11041 cctgcgtcag gcgatcgagg ataatggcga ggatcacaat cccgacgccg ccaacggtgg
    11101 caagccccat atccagacga ccgataccgc gaagtaccat ctgacccagc ccgccgacgg
    11161 caatcatcga ggcaatgacc accatagaaa gggccagcat cagcgtctgg ttaacgcccg
    11221 ccataatggt cggcatcgcc agcggtaact gaactttgaa cagcatctgg cgcgggctgg
    11281 caccgaatga gcgcgaggct tcaatcagat ccgccggaac ctggttaatc cccagaatgg
    11341 tcagacggat aatcggcggc agagcaaaga tgatcgtcac caccacgccc ggcacgttac
    11401 cgataccaaa tagcatgacg attggcacca gataaacaaa cgctggcgtg gtctgcatgg
    11461 catcaagcag tggacgaata attttcgccg ctcgcggact tctcgccagc cagatcccca
    11521 gcggcaaacc aatgacgata cagaacagca gggcggttaa caccagcgcc agggtaacca
    11581 tggcctgcga ccaggcaccg attgcgccga tggcaatcag cgaaaccagc gtcgccacgc
    11641 ccattccgac cccggaaatc tgccaggcga tgagagcgaa aacgataatc gccaccggtg
    11701 cgggcatacc cagcagcaat tgctggaaac cgttgagaat gtaatcaacc ggaacgcgca
    11761 cgccctggaa gacgggacgg aaatgggtaa caacccagtc gatcccttca gtgacccaac
    11821 tgtcgagcgg gatcagcgtt ttatggaacg gatcgagaat attaaaatgc tcgacgtttg
    11881 gcgcaggcgt actggtcagc cagtcagcac caccgccgtc agtcggtgca gtcgccggtg
    11941 taccccaggc gtctgcggat tgcacggcac tgtccgccgc tggcgtggta tcccacggat
    12001 tattttgatc agccattatt tcccccctca cgatctaaag cacgcagcag cattcctttc
    12061 gaaatgatgc cgacatactg ttggtcctcg tcgaccacgg gcaccgcaca gggtgcctgt
    12121 ccgacatgag agagcaactc gctaagaggc gtttgtgcat cgactgctaa cggcgcatca
    12181 atcagcgccg catcaagacc ttgctgctgc gttaacgcgg ttttaagcga atcgatggaa
    12241 actgcgccga caaacttatt accgcgttcg ataacgtagc catattcgcg atcttcatcc
    12301 tgcaataatt tcagtgccga acgtgggccg aagccagggg ttttacgaat taagccattc
    12361 ggtgtccggc gggcaatatc tttcgcactg aatacctgac taatatcaac gccacggaag
    12421 aaggtacgga cataatcatt cgccggatta ttgagaattt catccggtgt gccgacctgt
    12481 accacttcac cattttgcat aatggcaatt cggtcgccaa tacgcatagc ctcatcgaga
    12541 tcgtgggaaa taaagacaat ggtgcgctga tgtttcgcct gtaattttac cagctcatcc
    12601 tgcatctcgg tgcgaattaa tggatcgagc gccgagaagg cttcgtccat taataatata
    12661 tccggattaa tcgctaacgc gcgggctaat cccacacgtt gacgcatccc gccagagagt
    12721 tcatccgggt agctgtgggc ataattttcc agcccgacct gacgcagtgc atcaagggct
    12781 ttttcccggc gttcttcggc attaattccg gccaattcca taccgaacgc agtattgtcc
    12841 agcacggtca tatgcggcat taaggcaaag gactggaaga ccatcgcaat cttttttctg
    12901 cgcacctcac ggagttcggc atcggatatt ttggcaatat ccacaccatc aatcagcact
    12961 tgcccgcggg tgggttcaat caggcgattg agaaggcgta ccattgtgga tttacccgag
    13021 ccggataatc ccatgatgac aaatatctcg ccttcttcaa tggccagact ggcgtctttt
    13081 acgccaagcg atagcccagt tttttccaga atttgttctt tcgaaagtcc ttgttcgata
    13141 tatttgaacg ctcgctgtgg atgctcgcca aatattttat aaagattttt aatttctaat
    13201 ttaattgcca tgcaatagaa agattccttt atttgtttat gtcgatatat tacccaatgg
    13261 aaatagtcac ttttttctac cctaacatac tgagaatctg aggcaacccc tgagggcaaa
    13321 tgtggcatga atattgatgc gagcaaatcg ccggaatttc ccgtgatata agggctgaga
    13381 gcaaatcgag aaaagttgat attttttgtc atagatagcg aaaaaacgcc tgaatattgt
    13441 agtttcaggc gaataatgca acagagtatc agtgtagatc actacagaat atttgcgtga
    13501 taaaaagcta tttggcggga attatttccc tgctgcgggt agtgatattt ttgaaaataa
    13561 caccctcaga aattccagtc ttcatcttct gtttcaaccg ctttccccat cacataagag
    13621 gagcctgaac cggaaaagaa atcgtgattt tcatcggcat tcggcgaaag cgcggcgagg
    13681 attgccggat tcacttccgc catttctgcg ggaaataacg gttcgtagcc cagattcatc
    13741 aaagccttat tggcgttgta acagagaaac gctttcacat cgtcagccca cggggtttcg
    13801 gcgtacagct catcggtgta ttgcaactcg ttgtcgtaga gttccagcaa caaatcgaag
    13861 gcgaaactct tcaactcttc acgttgtccc agagatatct tttccatgtt tttctgatat
    13921 ttatagccta tgtagtaacc gtggactgct tcatcgcgga taatcagacg gatcagatct
    13981 gcggtattgg tcagctttcc gcggctggaa aaatacatcg gcagccagaa accggaatag
    14041 aacaaaaaag attcaagaaa cacactggcg attttctttt tcagcggatc atcaccgcga
    14101 taatgttgct gaataatctg agcttttcgc tgcaacggtg cgttttcttc actccaggcg
    14161 taggcggcat cgacatcttt ggtctgacac agcgtcgaga aaatcgaact gtaagagcgg
    14221 gcatgaaccg cttccataaa gctgatattc gataatactg cctcttcatg aggcgtgagc
    14281 gcatcgggca tcagcgaagg cgcgccgata acattttgca gcgtgtcgag cagcgtcagg
    14341 ccagtaaaaa cgcgcattgt cagttgttgt tctacgacac ttaatgtctg ccatgcaggt
    14401 atatcgttcg acagtggcac cttttctggt agccagaaat tgctggtcag gcgattccac
    14461 acctccagat ctttatcgtc agatatcttg ttccagttga tggcgctgat acgtgagagt
    14521 ttcatagata ttccttaaag tgcacaggag acgcagcctt caatttcagt gccttccagc
    14581 gccatctgac gcaggcgaat gtaatagagc gttttgatac ctttgcgcca ggcgtaaatc
    14641 tgcgctttgt tgatatcgcg agtggtggcg gtatcgggga aaaacagcgt cagcgacaaa
    14701 ccctgatcga catggcgagt cgcttccgcg taggtgtcga tgatcttttc tgcgccgatt
    14761 tcgtaagcat cctgatacag cgccagattc tcgttagtca taaacggggc agggtagtaa
    14821 acgcgtcctg ttttgccctc tttgcgtatc tctactttcg ccacaatcgg atgaatactc
    14881 gacgtagcat ggttgatata agagatagaa ccggttggcg gcaccgcctg gagattctgg
    14941 ttgtatatgc cgtagcgcat cacgtcgtcg cgcagttgcg cccacatctc acgggtaggt
    15001 aacgtaatac cgctgcgggc aaacagttcg ccaactttcg ccgttttcgg ctgccagtta
    15061 ccttgcagat attggctgaa atattcacca ctggcatagc gtgactgttt gaacccggcg
    15121 aaggtttcac cgcgttcgcg cgccagcaac atcgaggtac gcagtgcgtg ccaggtgatg
    15181 gtatagaaat agagattggt gaaatccagg gcttccggcg aaccataagc gatgccttcc
    15241 ctcgccagat aaccatgtaa attcatctgc cccagtccga tggcgtgcga ggcggcattt
    15301 ccggcttcga tggacggcac gctgcggata tgactcatat ctgacaccgc cgttaaaccg
    15361 cgtacggcag tctctaccgt gcgggcaaag ttgggggaat ccatggtgtg ggcaatattc
    15421 aacgaaccta aattgcagga aatatcatgg cctgtacggg catagtcgag attctcgtca
    15481 tactctgagg cgctgttaac ctgcaaaatt tctgagcaga gattactcat atttatgcgc
    15541 ccggcgatag ggttagcacg gtttaccgtg tcttcataca tgatgtaggg atagccggac
    15601 tcaaactgga tttctgccag tcgctggaag aaatcacggg cgttgaggta ttttttgcgg
    15661 atgcgttcat cggcaaccag ttcgtcatag tgttcgctaa tggcgatatc ggcaaacggc
    15721 ttgccataaa ctcgctcaac gtcatagggc gaaaacagcg ccatctgcgc attctctttt
    15781 gccagatgga aagtgatatc cgggatcacc acgccaagcg acagtgtttt aatgcggatt
    15841 ttttcgtcgg cattttcccg tttcgtgtcg agaaaacgca gaatatcggg atgatgagca
    15901 tgtaaataga ctgcaccagc cccctgacgc gcgccgagtt ggttggcata ggaaaatgcg
    15961 tcttccagca ttttcatcac cggaattacg ccagaagatt gattttcaat acgtttaatt
    16021 ggcgcgcccg cttcccgcag attcgacagc aaaaatgcca cgccgccgcc gcgtttcgac
    16081 agttgcagtg cggaatttac cgcccggcca atcgactcca tattgtcttc aatacgcagc
    16141 agaaaacagg aaaccagttc gccgcgctgc tgcttaccgc agttgaggaa tgttggcgtg
    16201 gctggctgaa agcgtcctga cagcatttca tcggtcagtt gcaacgccag cgtcgcatcg
    16261 ccttgtgcca gcgtcagcgc caccatcgtg actcgatcgg caaaatcttc cagataacgt
    16321 ttaccgtcga atgtcttcaa cgtatagctg gtgtaaaact tccatgcccc gaggaatgtc
    16381 tggaaacgaa aaccgctggt gtgtgcgtgg gcaaacagcg taatgacaaa gtcgcgagag
    16441 tagcgattaa gaacgctttc atcatagtaa ccttcgttga ccagccagtt caggcgctgc
    16501 tgctggctac tgaaggtcac actgttcgga cgcacatgcg tcgcaataaa ggcgtcaacg
    16561 gcctggcggt ctttatcgaa ctgaatgcga cctgcgctat cgtagaggtt aagcatcgca
    16621 ttcagcgcgt ggtaatccat cgtttcctgc gtcaggcatt ctgcggttgt cgttgccaaa
    16681 attcggttac tcctttacga acgttttcga tatcgctttg cgtacccatg agttcaaaac
    16741 ggtacagcca cggcacgccg catttccggg caatcacatc tccggcgcgg ccatacgcct
    16801 caccaaagtt gcgattacca gaagcaataa cgctgcgaag caacgcccgg ttgtgctcgt
    16861 cgtttaaaaa gcgaattacc tgtcgtggca ccgcgccagc cgtaccgccg ccgccgtaag
    16921 agggcacgat caggatgtaa ggctcgtcta cctgaatccg ttcccgctca ttgagcggga
    16981 tgcgcaccgc gggcagacct aaacgttcga taaaacgctg cgtgttttcg gagctgctgg
    17041 agaagtagac gagctggctc atgcactggc cgcgtgtggc gctggatgca gacggttaat
    17101 catgtccgga cggaaaccag accagctaag atcgccagca atcactaccg gcaactgacg
    17161 aaagccctga gcacgcaacg cttccgctgc ttcaggaacg cgatcgacat taatcatttc
    17221 aaaatcaaag ccccggtttt ccatcgcccg tttggtggcg tggcactgaa cgcaatcgtt
    17281 acgagtgtaa atagtaatgc gcatgattcg tatttccgtt taaaatgaag atacggcgcg
    17341 atgatacgcg tcgggttgtc tctctgttga tacagagata ctagatgtag ttgaaaaaag
    17401 attcaaccac acaatatata gcaaatagtg gtcgaaatta ccctggatat gagcgtgacg
    17461 gggtaggggg atttttgtga ttcaccaggc aaaaagaaac cccgaagcca ggcttcgggg
    17521 tcaaagacgc gtatttatta tcatttttgc actacgattt gcgcatgctt aacagtgcgc
    17581 cgataaaaat acctaccgca gctgctgtac ccacgctaca ccagggtctt tcacgaacaa
    17641 aagaatccgc gcagccaacg gcatcgcgtg cggcttgctg gacgcgagta cgaccatgca
    17701 ttcgcgccct ggtttctttc agcaatgcct gagctttact gcgtgcggct tcagcttccc
    17761 ctttggcgtc gctgccccag gacttcaata cagattcgag gctgtcagct aattgattga
    17821 catcattctg gatatcctgc acgccatcat caacgtcgtt gcggttcggt cggttaaaca
    17881 tatgatcccc cattagaatt cgatgtaatt ttcagtgtag accataattt tcttaactga
    17941 ggttcatcgc ggctttatgg acttttctga aagcgttgtg aatgcgcaat caggtaaggt
    18001 aggcccgcgg ttgataataa cgaggatcaa atatgtattt acgaccagac gaggtggcgc
    18061 gcgtacttga aaaagtcggt tttactgtcg atgtggtaac ccagaaagcg tatggttacc
    18121 gccgtgggga aaattatgtc tatgttaatc gcgaagcgcg aatgggacgt accgctctgg
    18181 taattcatcc aacattaaaa gaacgcagtt caacactggc tgaacccgct tccgatatta
    18241 aaacttgcga tcattaccag caatttccgc tctatttagc aggcgagcga cacgagcatt
    18301 acggtatccc gcatggcttt agttcgcgtg ttgcgcttga acgttatttg aatggtttat
    18361 ttggcgaaac cagttaaaga cgcgactggc gatgccagtc gcgaaaagaa gagtcaggct
    18421 tttacctgct ggtaacggct gactttaaac agtcggcggc aataatcgag gaagtagcca
    18481 taaaccgccc ccatcaacat cgaaacaacg atgtttgaac tgaccgccgc cataatctga
    18541 tgccagtctg cgcccaccac taacaagatc gccacataca ccggtgactg gaacgtcaca
    18601 taagccagga tatcagccag attttttatc cagcccgacg ggctaacttt gcgtgccgcg
    18661 cgcataaaca gatcgcggta cataccgtat ggccatgcaa ttaagatgtt caccggaatc
    18721 gctaccaatc tggaataaaa agactgttcg aagctcattc cggagaggaa aacttcaata
    18781 cacatgttca cgacagaaca gtaaacaacc atcgcgaacg tatctgcaac tgcatgacgc
    18841 aagcgtgact gcggtgagaa catgctaatg ctccttaata aaagcgtaat gggatgttaa
    18901 tggagatgaa agcagtggat ctcattgcca tctgcatttt cgcatagcgt atatcgctgg
    18961 ctatgactat tcaattagtg aaaaattttt atttagtcag tttttgtaga taaaatattc
    19021 cgtaacggct cgttttttgt acattgtgga tttttacatg ccgatatgat ttattttcaa
    19081 ttaaatcaat tggatatgac ctttccttta atttcactaa tgaaagtttg ggggtgaggt
    19141 aacgctataa gcgtagagaa ttcggtgtat gtcgtgaccg tgtcatttac agc
//
LOCUS       DAPOAV010000081        19181 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.081, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000081 DAPOAV010000000
VERSION     DAPOAV010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19181
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.081"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..432
                     /locus_tag="RN951_003362"
     CDS             <1..432
                     /locus_tag="RN951_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416772.1"
                     /note="ElaD; specific cysteine protease which targets
                     ubiquitin and ubiquitin-like proteins covalently bound to
                     target proteins; SseL in Salmonella is required for
                     macrophage killing and virulence, and it is secreted by
                     the salmonella pathogenicity island 2 type III secretion
                     system; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deubiquitinase"
                     /protein_id="HDX2528316.1"
                     /translation="LGHDKENSLTRVINSFNSELMGEMSNNNIKVHLNEPEIIFLHAD
                     LQQYLSQSCGAFVCMAAQEVIEQRESNSDSAPYTLLKNYADRFKKYSAEEQYEIDFQH
                     RLVNRNCYLDKYGDARINASYTQLEIKHSQPKNRASGKRVS"
     gene            844..1450
                     /locus_tag="RN951_003363"
                     /pseudo
     CDS             844..1450
                     /locus_tag="RN951_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001544752.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1553..2056
                     /locus_tag="RN951_003364"
     CDS             1553..2056
                     /locus_tag="RN951_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HDX2528317.1"
                     /translation="MGMIGYFAEIDSEKINQLLESTEKPLMDNIHDTLSGLRRLDIDK
                     RWDFLHFGLTGTSAFDPAKNDPLSRAVLGEHSLEDGIDGFLGLTWNQELAATIDRLES
                     LDRSELRKQFSIKRLNEMEIYPGVTFSEELEGQLFASIMLDMEKLISAYRRMLRQGNH
                     ALTVIVG"
     gene            complement(2123..3580)
                     /gene="nuoN"
                     /locus_tag="RN951_003365"
     CDS             complement(2123..3580)
                     /gene="nuoN"
                     /locus_tag="RN951_003365"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416779.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoN"
                     /protein_id="HDX2528318.1"
                     /translation="MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIG
                     LNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNK
                     DEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYT
                     ILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGLMIVGLGFKL
                     SLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAIRVVLAII
                     AFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGEMSMEAVGVYLAGYL
                     FSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGF
                     IGKFYVLAVGVQAHLWWLVGAVVVGSAIGLYYYLRVAVSLYLHAPEQPGRDAPSNWQY
                     SAGGIVVLISALLVLVLGVWPQPLISIVRLAMPLM"
     gene            complement(3587..5116)
                     /gene="nuoM"
                     /locus_tag="RN951_003366"
     CDS             complement(3587..5116)
                     /gene="nuoM"
                     /locus_tag="RN951_003366"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit M"
                     /protein_id="HDX2528319.1"
                     /translation="MLLPWLILIPFIGGFLCWQTERFGVKVPRWIALITMGLTLALSL
                     QLWLQGGYSLTQSAGIPQWQSEFDMPWIPRFGISIHLAIDGLSLLMVVLTGLLGVLAV
                     LCSWKEIEKYQGFFHLNLMWILGGVIGVFLAIDMFLFFFFWEMMLVPMYFLIALWGHK
                     ASDGKTRITAATKFFIYTQASGLVMLIAILALVFVHYNATGVWTFNYEELLNTPMSSG
                     VEYLLMLGFFIAFAVKMPVVPLHGWLPDAHSQAPTAGSVDLAGILLKTAAYGLLRFSL
                     PLFPNASAEFAPIAMWLGVIGIFYGAWMAFAQTDIKRLIAYTSVSHMGFVLIAIYTGS
                     QLAYQGAVIQMIAHGLSAAGLFILCGQLYERIHTRDMRMMGGLWSKMKWLPALSLFFA
                     VATLGMPGTGNFVGEFMILFGSFQVVPVITVISTFGLVFASVYSLAMLHRAYFGKAKS
                     QIASQELPGMSLRELFMILLLVVLLVLLGFYPQPILDTSHSAIGNIQQWFVNSVTTTR
                     P"
     gene            complement(5280..7121)
                     /gene="nuoL"
                     /locus_tag="RN951_003367"
     CDS             complement(5280..7121)
                     /gene="nuoL"
                     /locus_tag="RN951_003367"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit L"
                     /protein_id="HDX2528320.1"
                     /translation="MNMLALTIILPLIGFVLLAFSRGRWSENVSAIVGVGSVGLAALV
                     TAFIGVDFFANGEQAYSQPLWTWMSVGDFNIGFNLVLDGLSLTMLSVVTGVGFLIHMY
                     ASWYMRGEEGYSRFFAYTNLFIASMVVLVLADNLLLMYLGWEGVGLCSYLLIGFYYTD
                     PKNGAAAMKAFVVTRVGDVFLAFALFILYNELGTLNFREMVELAPAHFADGNNMLMWA
                     TLMLLGGAVGKSAQLPLQTWLADAMAGPTPVSALIHAATMVTAGVYLIARTHGLFLMT
                     PEVLHLVGIVGAVTLLLAGFAALVQTDIKRVLAYSTMSQIGYMFLALGVQAWDAAIFH
                     LMTHAFFKALLFLASGSVILACHHEQNIFKMGGLRKSIPLVYLCFLVGGAALSALPLV
                     TAGFFSKDEILAGAMANGHINLMVAGLVGAFMTSLYTFRMIFIVFHGKEQIHAHAVKG
                     VTHSLPLIVLLILSTFVGALIVPPLQGVLPQTTELAHGSMLTLEITSGVVAVVGILLA
                     AWLWLGKRTLVTSIANSAPGRLLSTWWYNAWGFDWLYDKVFVKPFLGIAWLLKRDPLN
                     SMMNIPAVLSRFAGKGLLLSENGYLRWYVASMSIGAVVVLALLMVLR"
     gene            complement(7118..7420)
                     /gene="nuoK"
                     /locus_tag="RN951_003368"
     CDS             complement(7118..7420)
                     /gene="nuoK"
                     /locus_tag="RN951_003368"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoK"
                     /protein_id="HDX2528321.1"
                     /translation="MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASAL
                     AFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG"
     gene            complement(7417..7971)
                     /gene="nuoJ"
                     /locus_tag="RN951_003369"
     CDS             complement(7417..7971)
                     /gene="nuoJ"
                     /locus_tag="RN951_003369"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit J"
                     /protein_id="HDX2528322.1"
                     /translation="MEFAFYICGLIAILATLRVITHTNPVHALLYLIISLLAISGVFF
                     SLGAYFAGALEIIVYAGAIMVLFVFVVMMLNLGGSEIEQERQWLKPQVWIGPAILSAI
                     MLVVIVYAILGVNDQGIDGTPISAKAVGITLFGPYVLAVELASMLLLAGLVVAFHVGR
                     EERAGEVLSNRKDDSAKRKTEEHA"
     gene            complement(7983..8525)
                     /gene="nuoI"
                     /locus_tag="RN951_003370"
     CDS             complement(7983..8525)
                     /gene="nuoI"
                     /locus_tag="RN951_003370"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015959823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoI"
                     /protein_id="HDX2528323.1"
                     /translation="MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRY
                     RGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETKDGRWYPEFFRINFSRCIFC
                     GLCEEACPTTAIQLTPDFEMGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDG
                     KDKGEAENEAKPIDVKSLLP"
     gene            complement(8540..9517)
                     /gene="nuoH"
                     /locus_tag="RN951_003371"
     CDS             complement(8540..9517)
                     /gene="nuoH"
                     /locus_tag="RN951_003371"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015875065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoH"
                     /protein_id="HDX2528324.1"
                     /translation="MSWISPELIEILLTILKAVVILLVVVTCGAFMSFGERRLLGLFQ
                     NRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLAFAIVP
                     VSPGWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFL
                     GLSLMGVVAQAGSFNMTDIVNSQAHVWNVIPQFFGFITFAIAGVAVCHRHPFDQPEAE
                     QELADGYHIEYSGMKFGLFFVGEYIGIVTISALMVTLFFGGWQGPLLPPFIWFALKTA
                     FFMMMFILIRASLPRPRYDQVMSFGWKICLPLTLINLLVTAAVILWQAQ"
     gene            complement(9514..12240)
                     /gene="nuoG"
                     /locus_tag="RN951_003372"
     CDS             complement(9514..12240)
                     /gene="nuoG"
                     /locus_tag="RN951_003372"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311194.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoG"
                     /protein_id="HDX2528325.1"
                     /translation="MATIHVDGKEYEVNGADNLLEACLSLGLDIPYFCWHPALGSVGA
                     CRQCAVKQYQNAEDTRGRLVMSCMTPASDGTFISIDDEEAKQFRESVVEWLMTNHPHD
                     CPVCEEGGNCHLQDMTVMTGHSFRRYRFTKRTHRNQDLGPFISHEMNRCIACYRCVRY
                     YKDYADGTDLGVYGAHDNVYFGRPEDGTLESEFSGNLVEICPTGVFTDKTHSERYNRK
                     WDMQFAPSICQQCSIGCNISPGERYGELRRIENRYNGTVNHYFLCDRGRFGYGYVNLK
                     DRPRQPVQRRGDDFITLNAEQAMQGAADILRQSKKVIGIGSPRASVESNFALRELVGE
                     ENFYTGIAHGEQERLQLALKVLREGGIYTPALREIESYDAVLVLGEDVTQTGARVALA
                     VRQAVKGKAREMAAAQKVADWQIAAILNIGQRAKHPLFVTNVDDTRLDDIAAWTYRAP
                     VEDQARLGFAIAHALDNSAPAVDGIEPELQSKIDVIVQALAGAKKPLIISGTNAGSIE
                     VIQAAANVAKALKGRGADVGITMIARSVNSMGLGIMGGGSLEEALTELETGRADAVVV
                     LENDLHRHASATRVNAALAKAPLVMVVDHQRTAIMENAHLVLSAASFAESDGTVINNE
                     GRAQRFFQVYDPAYYDSKTVMLESWRWLHSLHSTLLSREVDWTQLDHVIDAVVAKIPE
                     LAGIKDAAPDATFRIRGQKLAREPHRYSGRTAMRANISVHEPRQPQDIDTMFTFSMEG
                     NNQPTAHRSQVPFAWAPGWNSPQAWNKFQDEVGGKLRFGDPGVRLFETSENGLDYFTS
                     VPARFQPQDGKWRIAPYYHLFGSDELSQRAPVFQSRMPQPYIKLNPADAAKLGVNAGT
                     HVSFSYDGNTVTLPVEIAEGLTAGQVGLPMGMSGIAPVLAGAHLEDLKEAQQ"
     gene            complement(12293..13630)
                     /gene="nuoF"
                     /locus_tag="RN951_003373"
     CDS             complement(12293..13630)
                     /gene="nuoF"
                     /locus_tag="RN951_003373"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HDX2528326.1"
                     /translation="MKNIIRTPETHPLTWRLRDDKQPVWLDEYRSKNGYEGARKALTG
                     LSPDEIVNQVKDAGLKGRGGAGFSTGLKWSLMPKDESMNIRYLLCNADEMEPGTYKDR
                     LLMEQLPHLLVEGMLISAFALKAYRGYIFLRGEYIEAAVNLRRAIAEATEAGLLGKNI
                     MGTGFDFELFVHTGAGRYICGEETALINSLEGRRANPRSKPPFPATSGVWGKPTCVNN
                     VETLCNVPAILANGVEWYQNISKSKDAGTKLMGFSGRVKNPGLWELPFGTTAREILED
                     YAGGMRDGLKFKAWQPGGAGTDFLTEAHLDLPMEFESIGKAGSRLGTALAMAVDHEIN
                     MVSLVRNLEEFFARESCGWCTPCRDGLPWSVKILRALERGEGQPGDIETLEQLCRFLG
                     PGKTFCAHAPGAVEPLQSAIKYFREEFEAGIKQPFSNTHLINGIQPNLLKERW"
     gene            complement(13627..14127)
                     /gene="nuoE"
                     /locus_tag="RN951_003374"
     CDS             complement(13627..14127)
                     /gene="nuoE"
                     /locus_tag="RN951_003374"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoE"
                     /protein_id="HDX2528327.1"
                     /translation="MHENQQPQTEAFELSAAEREAIEHEMHHYEDPRAASIEALKIVQ
                     KQRGWVPDGAIHAIADVLGIPASDVEGVATFYSQIFRQPVGRHVIRYCDSVVCHINGY
                     QGIQAALEKKLNIKPGQTTFDGRFTLLPTCCLGNCDKGPNMMIDEDTHAHLTPEAIPE
                     LLERYK"
     gene            complement(14130..15932)
                     /gene="nuoC"
                     /locus_tag="RN951_003375"
     CDS             complement(14130..15932)
                     /gene="nuoC"
                     /locus_tag="RN951_003375"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit C/D"
                     /protein_id="HDX2528328.1"
                     /translation="MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATR
                     TGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHREGLPAADFSVFYHL
                     ISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMM
                     PQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFL
                     NLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIE
                     YLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMT
                     PVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLA
                     SYEKAALQNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENF
                     DFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERT
                     LQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSY
                     AHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR"
     gene            complement(16026..16688)
                     /gene="nuoB"
                     /locus_tag="RN951_003376"
     CDS             complement(16026..16688)
                     /gene="nuoB"
                     /locus_tag="RN951_003376"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoB"
                     /protein_id="HDX2528329.1"
                     /translation="MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLND
                     MVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTC
                     FTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPP
                     RPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQSERERKRGERIAVTNLRTPD
                     EI"
     gene            complement(16704..17147)
                     /gene="nuoA"
                     /locus_tag="RN951_003377"
     CDS             complement(16704..17147)
                     /gene="nuoA"
                     /locus_tag="RN951_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoA"
                     /protein_id="HDX2528330.1"
                     /translation="MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARAR
                     SKNVPFESGIDSVGSARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVE
                     AAIFIFVLLAGLVYLVRIGALDWTPARSRRERMNPETNSIANRQR"
     gene            complement(17778..18716)
                     /gene="lrhA"
                     /locus_tag="RN951_003378"
     CDS             complement(17778..18716)
                     /gene="lrhA"
                     /locus_tag="RN951_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LrhA"
                     /protein_id="HDX2528331.1"
                     /translation="MITANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQ
                     QMQRLEQLVGKELFARHGRNKLLTEHGIQLLGYARKILRFNDEACSSLMFSNLQGVLT
                     IGASDESADTILPFLLNRVSSVYPKLALDVRVKRNAYMAEMLESQEVDLMVTTHRPSA
                     FKALNLRTSPTHWYCAAEYVLQKGEPIPLVLLDDPSPFRDMVLATLNKADIPWRLAYV
                     ASTLPAVRAAVKAGLGVTARPVEMMSPDLRVLSGVDGLPPLPDTEYLLCYDPSSNNEL
                     AQVIYQAMESYHNPWQYSPMSAPEGDDSLLIERDIE"
BASE COUNT         4876 a         5249 c         4859 g         4197 t
ORIGIN      
        1 ctaggccatg ataaagaaaa ttcacttacg cgtgtcatta atagttttaa ttctgaactc
       61 atgggagaaa tgtcgaataa taatataaaa gttcatttaa atgaaccaga gataatattt
      121 ttacatgccg atcttcagca atacttaagc caaagttgcg gtgcgtttgt gtgcatggca
      181 gcccaggaag tgattgaaca aagggaaagc aattctgaca gcgcccccta tacgttatta
      241 aaaaactatg ctgacagatt taaaaaatat tcagcagaag agcagtacga aattgatttt
      301 caacatcgac tggtaaacag aaattgttat ttagataaat atggcgatgc acgaatcaat
      361 gcttcttata cacaattaga aataaaacac tcacaaccca aaaatagagc atccggcaaa
      421 agagtgagtt aacatcattg ttaatcaatt cgaccagtca gcaaatatgc tgactggtcg
      481 aacatagttt gctaaacagt catcactgac tgatgtcagt cacaccatcc gccagttcaa
      541 tcttcgggta tttccagcgt atctcggcac gcgattgctg gtctgttgat gtagtggatt
      601 gttgttgctg acttttctta ccctcagagt tctgccccct gtcaactcaa tctgccaata
      661 aataacataa ttatattttt ccttatatga attccttttt aaaatagcga agccactgta
      721 aaagatactt tttgtataga tctaacaacc gtaataaaac aaacactcat aactcattat
      781 aaataatgat aaaataacgt cttttattga taatttatat atgaaaaaaa atccttttgt
      841 tatattattt ctgatttcac tccctctgat tatttttacc aaccctgggt cactgcatta
      901 tcgccaacgc cccgacacgt cagtcctgag caattagaaa aaacagttcg ttatcttaca
      961 caaactgtgc atccacgtaa tgccgacaat attgataatc tgaataggtc cgtagagtat
     1021 ataaaagagt tctttgtcag tagcggtgcc agagttaccg cgcagggcgt ccccgattgg
     1081 ctattacgac tctgcgcctg gtagccagga ttacccttac ccgcaatgtc ctggctttat
     1141 cccgatcggg gggactttat tgcctggtcg gcagaataca ggatatcaac gccgttcgtc
     1201 aggtaaaaac ggcattgtta tcatcccggg atttatctgt ttattctatg aatgccccat
     1261 ggtttattcc cggtattgat ttctctgacc acctgaatta ttggcaacac gatattcccg
     1321 ccgtaatgat tactgacacc gctttttatc gtaataaaca ataccacttg cccggtgata
     1381 cagcagacag attgaattat cagaaaatgg ctcagatggt gttataacct tgttacacaa
     1441 cagtaaataa taaaaatttc tcgaggcggg tccagaaaca gcgacatgta cattttattt
     1501 tccctcgtct gttttaagat gcgaaacata aaattcaatg gaggaaaaat aaatgggaat
     1561 gattggttat tttgcagaaa ttgactcaga aaagattaac caactgcttg agtctactga
     1621 aaaacctttg atggataata tacatgacac gctttcagga ttacgccgac tggatattga
     1681 taaacgctgg gattttttac actttgggct gacaggcacc tctgcttttg atcccgcgaa
     1741 gaatgatccg ctgagtcgtg ccgtgcttgg tgaacacagc ctcgaagatg gcatagatgg
     1801 cttcctggga ttgacctgga atcaggaatt agccgcgaca atcgaccgac tggaatcact
     1861 ggatcgaagt gagctgcgta aacagttttc cattaagcga ctcaatgaaa tggagattta
     1921 tccgggagtg accttttcag aagagttaga ggggcaactc tttgcctcga tcatgcttga
     1981 tatggaaaag ctgattagcg cgtatcgacg tatgctgcga caagggaatc atgcgctgac
     2041 ggttattgtt gggtgatggt gtcagagcgc caaaaaaaac cgccgaacat gtcggcggct
     2101 ttctgactta caaactaaca gattacatca gcggcattgc taaccgcaca atactaatca
     2161 gcggttgtgg ccatacaccc agcaccagta ccaacagtgc agaaatcagc accacgatac
     2221 cgcccgcgct gtactgccag tttgacggtg catcgcgacc cggttgttcc ggtgcgtgca
     2281 ggtacaggct caccgccacg cgcaggtagt agtagaggcc gattgccgaa ccgacaacca
     2341 cggcacccac cagccaccac aagtgtgcct ggacaccgac cgccagcacg tagaacttac
     2401 cgataaagcc cagcgtcatc gggataccgg ccagagacag catcatcacc gtcatcactg
     2461 ccgcgaggat cggacgatgc cagaacagac cgcggtaaga gaacagggaa tcagcatccg
     2521 ggccacgata cgggctggac atcaggctga ccacgccgaa cgcgccgagg ctgctgaaca
     2581 gataaccggc cagataaacc cctaccgctt ccatcgacat ctcgccggtt tgcagcgcaa
     2641 tcagcgctac cagcagatag ccgaggtgag agatagatga gtaaccgagc agacgtttga
     2701 tattggtctg gctcagcgcc atcaggttac cgaagatgat ggaggcaaag gcgataatcg
     2761 ccagcaccac gcgaatcgct tcgctgtcac ccaccggtgc gtagaggaac agacgcatca
     2821 ccacaccgaa gatagcgatt ttgctcgccg tcgccaggaa agtggaaacc ggcgcaggcg
     2881 cgccctggta tacgtctggc gtccacaggt ggaacggcac cagagagagt ttgaagccga
     2941 ggccaacaat catcaggccg aaacctgcca gcaacagcgg ctcgttgagc ataccgtcgc
     3001 caaggttttt acccaacgcg acaaacgaca ggtcgccaga ctgcgcatac accagcgcca
     3061 taccaaacag caggaaagaa gacgctgcgg cagaaaggat ggtgtatttg atactggctt
     3121 ccagtgaacg tttctggcgg aaagcgtaac cgaccaggcc aaacagcggc aaagagatca
     3181 gttcgatacc gaggaacaga gacgccagat ggttggcatt cgccagcagg atcccgccca
     3241 gcgcggcaat taacaccaac aggtagaact catccttgtt gtcgttatag ccttcaagcc
     3301 acgggtaggc gaaagtacag gtggcgaggc tcgccaacaa taccagcccg gtgtaaagca
     3361 tggcgaaacc atcaacgcgc atcagcggcg taacgtccat agcgcccgcc tggccaacaa
     3421 accagagcga aaccagcgcc gcgttaagcc caataaccga gagcgtagcg ttgaggaaat
     3481 gattgcgtcg ccacgcaatg gagagcatca caaccaccac cgtcaagccg acgatcagca
     3541 acggtagcag tgcgatcagg ttttgtggag ttattgtcat ggcgatttac ggccttgtag
     3601 tagtaacgga attaacaaac cactgctgga tattgccaat cgcggagtgc gaggtatcca
     3661 gaatcggctg cggatagaag cccagcagta ccagcagcac caccagcaac aggatcataa
     3721 acagctcacg cagcgacatc cctggcagtt cctggctggc aatctggctt ttcgctttac
     3781 cgaagtaagc gcgatgtaac atcgccagcg aataaacaga tgcaaagacc agcccaaagg
     3841 tagagataac ggtaatcacc gggacaacct ggaagctgcc gaacagaatc ataaattcgc
     3901 cgacgaagtt accggtgcca ggcatcccaa gcgttgccac cgcaaagaac agcgacagtg
     3961 ctggcagcca tttcatcttg ctccacagac cgcccatcat gcgcatgtcg cgggtatgga
     4021 tacgttcata aagctgacca caaagaataa acagacccgc cgccgacaaa ccgtgcgcaa
     4081 tcatctggat taccgcgccc tggtaggcca actggctgcc ggtgtagata gcaatcagca
     4141 cgaagcccat gtgggaaacc gaggtgtagg cgatcagacg tttgatatcg gtctgggcga
     4201 aggccatcca cgcaccgtag aagatgccga taacacccag ccacatagca attggcgcga
     4261 actctgccga cgcgttcggg aacagcggca gggagaaacg cagcaaaccg taagcggcag
     4321 ttttcagcaa gatccccgcg aggtcaacgg aaccggcggt cggagcctgg gagtgcgcat
     4381 ccggcagcca gccatgcagc ggaaccaccg gcattttgac tgcgaaggcg atgaagaagc
     4441 ccagcattaa caggtattcc acaccactgg acattggcgt attcagcagc tcttcatagt
     4501 tgaaggtcca gacgccggtc gcattgtagt gaacaaaaac cagcgccagg atggcaatca
     4561 acatcaccag gccactcgcc tgggtgtaaa tgaagaactt ggttgccgcc gtgatacgcg
     4621 ttttaccgtc agaggcttta tgcccccaca gtgcgatcag gaagtacatc ggcaccagca
     4681 tcatttccca gaagaagaag aacaggaaca tgtcgatggc aaggaacacg ccgataacgc
     4741 cgcccaggat ccacatcagg ttgaggtgga agaagccctg atatttttcg atctctttcc
     4801 acgaacagag taccgccagc acaccgagca gaccggtcag cacgaccatc agcagcgaca
     4861 gaccgtcaat ggcgagatga atagagatac caaaacgcgg gatccacggc atgtcgaatt
     4921 cagactgcca ctgcggaatt ccggcggatt gcgtcagtga ataaccgccc tgcaaccaca
     4981 gttgcagcga cagcgccagc gtcaatccca tggtgatcag cgcgatccag cgcggcacct
     5041 tgacgccaaa gcgttcggtc tgccagcaca ggaagccgcc aataaaggga attaatatta
     5101 gccagggtag taacatggcg atctttattc cttgtaaaag tcccgtcagg accggatttt
     5161 caacgaattc tcacgacaga aaattctctt cggactgggg gtagtgtcgg atgcgccgcg
     5221 aaggcagctt atccgaccta cgttcttata tgcccagggg caatcccaca atccttaact
     5281 caacgcagta ccatcaacag tgccagcacc acgaccgcac cgatgctcat ggatgccaca
     5341 taccagcgca gataaccgtt ctcgcttaac agcagacctt tacctgcaaa gcgggaaaga
     5401 accgccggga tgttcatcat tgagttcagc ggatcgcgtt tcagcaacca ggcaataccc
     5461 aggaacggct tgacgaacac tttgtcgtac agccagtcaa agccccaggc gttgtaccac
     5521 caggtactca gcaggcggcc cggcgcactg ttggcgatgg aggtcaccag agtacgttta
     5581 cccagccaca gccaggctgc cagcagaatg ccgaccaccg cgaccacgcc agaggtaatt
     5641 tccagggtca acatgctgcc gtgcgccagt tccgtcgttt gcggaagcac gccctgcagc
     5701 ggcggtacaa tcagtgcgcc aacgaaggtg gaaaggatca gcagcacaat cagcggcagg
     5761 ctgtgagtta cccctttcac ggcgtgagcg tgaatttgtt cttttccgtg gaagacgatg
     5821 aaaatcatac ggaaggtgta gagcgaggtc ataaacgcac cgaccagacc tgccaccatc
     5881 agattgatat gaccattcgc catcgcaccc gcgaggatct catccttact gaagaagccc
     5941 gcagtgacca gcggcagtgc cgacagtgct gcgccgccca ccaggaagca gagataaacc
     6001 agcggaatag atttacgcag accgcccatc ttgaagatgt tctgttcgtg atggcaggcc
     6061 agaatgacgg aaccggatgc caggaacagc agcgctttaa agaacgcgtg agtcatcaag
     6121 tggaaaatcg ccgcatccca tgcctgcacg ccaagcgcga ggaacatgta gccaatctgg
     6181 ctcatggtag agtaagcgag aacacgtttg atgtcggtct gtaccagcgc ggcaaaaccg
     6241 gccagcagca gcgtaaccgc cccgacaata cccaccagat gcagaacttc cggcgtcatc
     6301 aggaacaggc cgtgggtacg ggcgatcagg tagacacccg cggttaccat cgttgcggcg
     6361 tggatcagcg cggagacagg cgtcgggccc gccatcgcgt cagcaagcca tgtctgcaac
     6421 ggcaactgcg cagatttacc gaccgcaccg cccagcagca tcagcgtcgc ccacatcagc
     6481 atgttattgc cgtcagcaaa gtgcgctggt gccagttcca ccatttcgcg gaagttcagg
     6541 gtgcccagtt cgttgtaaag aatgaacagt gcgaaagcga ggaaaacgtc acccacacgg
     6601 gtcacgacga acgctttcat tgccgctgcg ccattcttcg gatcggtgta atagaaaccg
     6661 atcagcagat aggagcacag gcccacgcct tcccagccga ggtacatcag cagcaggtta
     6721 tcggcgagaa ccagaactac catgctggcg atgaacaggt tggtgtaggc gaagaagcga
     6781 gagtagccct cttcaccgcg catgtaccag gaggcgtaca tgtgaataag gaaacccaca
     6841 ccagtgacca ccgagagcat ggtcagcgac aggccgtcca gcaccaggtt aaaaccgatg
     6901 ttaaagtcgc ctaccgacat ccacgtccac agcggctggc tgtatgcctg ctcgccgtta
     6961 gcgaagaaat caacgccgat aaaggcggtt accagcgccg ccaggcccac agagccaacg
     7021 ccgacgatcg ccgaaacgtt ttcagaccag cgcccacggg agaacgccag caggacgaag
     7081 ccaatcaatg gcaaaataat ggttaaggca agcatgttca tccgcgcatc tcacttactg
     7141 aatcgatgtt caggttctgg cgacgacggt gaagttgcag cagcagcgca aggccgatac
     7201 tcgcttctgc cgccgcgagg ctgatggcga gaatgtacat cacctgaccg tcggtctgac
     7261 cccagtagct tccggcgacc acaaaggcca gcgcggaggc gttaatcatg atttccagac
     7321 caatcagcat aaacagcaga ttgcgacgga taaccagacc ggttaagcca agaacgaata
     7381 agattgccgc gaggatcagt ccatgttgta aggggatcat gcgtgctcct ccgtttttct
     7441 tttcgcgctg tcgtctttac gattgctcag cacttcaccc gcacgctctt cacgaccgac
     7501 gtggaaggcc acaaccagac ccgcgagcag cagcatagaa gccagttcca ccgccagtac
     7561 gtaaggcccg aacagcgtaa tacccactgc tttagcactg attggcgtac cgtcgatacc
     7621 ctgatcatta acaccaagga tggcgtaaac aatcaccacc agcatgatgg ccgacaaaat
     7681 tgccggacca atccacacct gcggtttcag ccactggcgt tcctgttcga tttctgaacc
     7741 gcccaggttg agcatcatca ccacgaacac gaacagcacc ataatggcac ccgcgtagac
     7801 gataatttcc agcgcaccgg cgaagtaagc gcccagtgag aagaacaccc cggaaatcgc
     7861 cagcagcgaa ataatcaggt acagcagtgc gtgtaccgga ttggtatggg tgatcactcg
     7921 caaggtcgca agtatggcta tcaggccaca gatataaaaa gcgaactcca ttgcccctct
     7981 ccttacggta acaggctctt gacgtcgata ggcttggctt cgttctctgc ttcgccctta
     8041 tctttgccgt cgattgccat acctgccatc cggtagaagt tatattccgg gtatttgccc
     8101 ggaccggaga tcagcagatc ctctttttcg taaaccagat cctggcgctt gtattccccc
     8161 atttcgaaat ccggggttaa ctgaatcgcc gtggtcggac aggcttcttc gcacagacca
     8221 cagaaaatgc agcgtgagaa gttgatgcgg aaaaattccg ggtaccagcg accgtctttg
     8281 gtttctgctt tttgcagcga gatacagccg accgggcagg ctaccgcgca gaggttacag
     8341 gctacgcaac gctcttcgcc gtccgggtcg cgggtcagaa cgatacgacc acgataacgg
     8401 ggcggcagat agaccggctc ttccgggtac attcgcgttt cgcgtttggc gaacgcgtgc
     8461 aggccgatca tccagatact acgaacctgg gtgccgaaac ctactaacaa ttcttttaag
     8521 gtcatggtct tattgcccct tattgcgcct gccagagaat gacagccgcc gttaccagca
     8581 agttgatcag cgtcagcggc aggcagattt tccagccgaa ggacattacc tggtcataac
     8641 gcggacgcgg taacgacgca cgaatcaaaa tgaacatcat cataaagaac gcggttttca
     8701 gcgcgaacca gatgaatggc ggtaacaacg ggccttgcca gccaccgaag aacagcgtca
     8761 ccatcaatgc agagatggtc acaatcccga tgtactcacc cacgaagaac agaccgaact
     8821 tcataccgga atattcaatg tggtaaccat ccgccagttc ctgctcggct tccggctggt
     8881 caaacgggtg acggtgacat accgccacgc ccgcgatggc aaaggtaata aaaccaaaga
     8941 attgcgggat aacgttccac acatgcgcct ggctgttgac gatgtcggtc atgttgaatg
     9001 aaccggcctg cgccaccacg cccatcaggg aaagcccgag gaacacttcg tagctcaggg
     9061 tctgcgcaga agcacgcatc gcacccagca acgagtattt gttgttactt gaccagcccg
     9121 caaacagcac cgcgtaaacc gccagacctg ccatcatcag gaagaacaaa atcccgatgt
     9181 tcaggtcggc aaccacccaa cccggactga ctggcacaat cgcaaaggcc agcagcagcg
     9241 aggtaaaggc aatcatcggt gccagggtaa agatgacgcg atccgagaat ttcgggatcc
     9301 agtcttcttt aaagaacatt ttgatcatgt ccgcaaccag ctggagcgaa ccgccccagc
     9361 caacacggtt aggtccgtaa cggttctgga acagacccag caggcgacgt tcgccaaagc
     9421 tcatgaatgc cccgcaggtg acaaccacca gcaggatcac caccgctttg aggatggtca
     9481 gcaggatctc aatcagttcc ggtgatatcc aactcattgt tgtgcctcct tgagatcctc
     9541 aagatgcgcg ccagccagca ccggagcaat accggacata cccatcggca agcccacctg
     9601 ccctgccgtc agcccttcag cgatttcaac cggcagcgtg accgtgttgc catcgtaact
     9661 aaaggagacg tgtgtacctg cgttcacacc taacttcgcg gcatccgctg ggttgagttt
     9721 gatgtacggc tgcggcatac ggctctggaa gaccggagca cgctgtgaca attcatcgct
     9781 gccaaacagg tggtaatacg gcgcgatacg ccatttcccg tcctgcggct ggaagcgtgc
     9841 cggtacgctg gtgaagtaat ccagaccatt ttcgctggtt tcaaacagac gcacgcccgg
     9901 atcgccaaag cgcagtttgc cgcccacttc gtcctggaat ttgttccacg cctgcgggga
     9961 gttccagccc ggcgcccagg caaacggcac ttgcgaacgg tgcgcagtcg gctggttgtt
    10021 accttccatc gagaaggtga acatggtgtc aatatcctgc ggctgacgcg gctcatgaac
    10081 gctgatattg gcgcgcatgg cggtacgacc gctgtaacgg tgcggttcac gggccagttt
    10141 ctgcccacga atacggaatg tcgcatccgg cgcagcatct ttgatacctg ccagttccgg
    10201 gattttcgcc acaacagcgt caatcacatg gtcgagctgc gtccagtcca cttcacggct
    10261 cagcagggtg ctgtgcagcg agtgtaacca gcgccagctt tccagcatga cagttttgct
    10321 gtcgtaataa gcaggatcgt aaacctggaa gaaacgttgg gcgcggcctt cgttgttgat
    10381 caccgtaccg tcgctttcag caaagctggc agcagaaagt accagatggg cgttttccat
    10441 aatcgctgtg cgttgatgat caaccaccat caccagcggc gctttagcca gcgcagcatt
    10501 cacgcgggta gcggaagcgt gacgatgcag atcgttttcc agcaccacca ccgcgtcggc
    10561 gcgtccggtt tccagttcgg tcaacgcttc ttcaagcgaa ccgccaccca taatgcccag
    10621 ccccatgctg ttgacggaac gggcaatcat ggtgatacca acgtcagcgc cgcgaccttt
    10681 cagggctttc gcgacgttag ccgcagcctg aatcacctct atgctaccgg cgttcgtccc
    10741 ggagataatc aacggtttct tcgcacctgc cagtgcctgc acgatgacgt cgattttgct
    10801 ttgcagctca ggttcgatac cgtcaaccgc tggcgcagag ttatccagcg catgggcgat
    10861 ggcaaaacct aaacgcgcct gatcttcaac cggtgcgcgg taagtccacg ccgcgatatc
    10921 atccagacgg gtgtcatcaa cgttggtaac aaacagcgga tgcttcgcac gttgaccgat
    10981 gttgaggatt gccgcaatct gccagtcagc cactttctgt gctgccgcca tttcgcgcgc
    11041 tttacctttc acagcctgac gcactgccag cgcgacgcgc gcgccggtct gggtaacgtc
    11101 ttcgcccagc accagtaccg catcgtaaga ttcgatttcg cgcagagccg gagtataaat
    11161 gccgccttca cgcagcactt tcagcgccag ttgcagacgt tcctgctcac cgtgagcgat
    11221 accggtgtag aagttttctt cgcccaccag ttcacgcagc gcaaagttgc tttccacgct
    11281 ggcacgcgga gaaccaatac cgatcacttt cttcgactga cgcagaatat ctgccgcgcc
    11341 ctgcattgcc tgttcggcgt tgagggtaat gaaatcatcg ccacgacgct gtactggttg
    11401 acgcggacga tctttcaggt tgacgtaacc gtaaccgaaa cgaccacggt cgcagaggaa
    11461 gtagtggttt accgtaccgt tgtaacggtt ttcgatacga cgcagttcgc cgtaacgttc
    11521 accggggctg atgttacagc cgatggaaca ttgctggcag atgctcggcg caaactgcat
    11581 atcccattta cggttgtaac gctcggagtg cgttttgtcg gtaaatacgc cggtcgggca
    11641 aatttcgacc aggttaccgg aaaattcgct ttccagcgtg ccgtcttccg ggcgaccgaa
    11701 gtagacgttg tcgtgcgcac cgtaaacgcc cagatccgta ccgtcagcgt aatctttgta
    11761 gtaacgcacg cagcggtagc aggcgatgca gcggttcatt tcgtgagaga tgaatggccc
    11821 caaatcctga ttacggtggg tacgtttggt gaaacggtag cgacggaagc tgtgtccggt
    11881 catcacggtc atatcctgaa gatggcagtt accgccttct tcacataccg gacagtcgtg
    11941 cgggtggttg gtcattaacc actcgaccac actttcacgg aactgtttcg cttcttcgtc
    12001 gtcaatggaa ataaaggtgc catcggaagc cggtgtcata caggacatca ccaggcgacc
    12061 acgcgtgtct tccgcgtttt ggtattgctt caccgcacac tggcggcaag caccgacgct
    12121 tcccagcgcc ggatgccagc aaaagtaagg aatatcaagg cccagagaca gacaagcttc
    12181 cagcaggttg tccgctccgt tgacctcgta ttctttgccg tctacatgaa ttgtagccat
    12241 tagcatgctt ccagttttct cggtcaggga ccgagcgtta atcgaaattc ggttaccagc
    12301 gctctttcag caggttcggc tgaatcccat taatcaaatg ggtattgctg aacggctgtt
    12361 tgattcccgc ctcaaattct tcgcggaaat atttgatggc gctctgtaac ggctccactg
    12421 caccaggtgc gtgggcacag aaagttttac ccgggcctaa gaatcgacac agttgctcaa
    12481 gtgtttcgat atcgcccggc tgaccttcac cacgctccag cgcacgcaga attttcacgc
    12541 tccacggcag accgtcgcgg cacggcgtac accagccgca ggactcacgg gcgaaaaact
    12601 cttccaggtt acgcaccagc gacaccatgt tgatctcatg gtcaaccgcc atcgccagcg
    12661 ccgtacccag acggcttccc gctttaccga tactttcgaa ttccatcggc aggtcaaggt
    12721 gcgcttcggt caggaagtcg gtgcccgcgc cgcctggctg ccaggctttg aatttcagac
    12781 cgtcacgcat accaccggcg taatcttcga ggatctcgcg cgcggtagta ccaaacggca
    12841 gttcccacag tcccggattt ttcacccgac cggagaagcc catcagcttg gtgccagcat
    12901 ctttactttt cgagatgttc tgataccact ccacgccgtt agcgaggatc gccggaacgt
    12961 tacacagggt ttcgacgttg ttgacacagg tcggtttgcc ccatacgccg gaggttgccg
    13021 ggaagggggg tttcgagcgt gggttagcac gacgcccttc cagggagttg attaacgctg
    13081 tttcttcccc gcagatgtag cgccctgccc cggtatggac gaacagttcg aagtcgaaac
    13141 ctgttcccat aatgtttttg ccaagcaagc ccgcttcagt ggcttcggca atggcgcggc
    13201 gcagatttac tgccgcttcg atatattcgc cacgcaggaa gatgtagcca cggtaagctt
    13261 tcagcgcaaa cgcggagatg agcatacctt ccaccagcag gtgcggcagt tgctccatca
    13321 gcaggcggtc tttataggtg cctggctcca tttcatcggc gttacacagc aggtaacgga
    13381 tgttcatgga ttcgtctttc ggcatcaggc tccatttcag gccggtagaa aagcccgcgc
    13441 caccgcgccc tttcagacca gcgtctttta cctgattaac gatttcgtcc ggagacagcc
    13501 cggtcagcgc cttacgcgcg ccttcgtaac cgtttttgct gcgatattcg tccagccaca
    13561 ctggctgttt gtcatcgcgc agacgccagg tcagcggatg cgtttcggga gtacggataa
    13621 tgtttttcat ttataccgct ccagcagttc agggatcgct tccggggtca gatgcgcgtg
    13681 agtatcctca tcgatcatca tgtttggccc tttatcacag ttccccaggc agcaagttgg
    13741 cagcagcgta aagcgaccgt caaatgtcgt ttgccctggt ttgatgttta gctttttctc
    13801 gagcgccgcc tgaataccct ggtaaccgtt gatatgacag accacgctgt cgcaataacg
    13861 gatcacatgg cgaccaaccg gctggcggaa gatctgactg tagaacgttg ccacaccttc
    13921 gacgtcgctt gccggaatac ccagcacatc ggcgatcgcg tggatcgcac catccggcac
    13981 ccagccacgc tgcttctgaa cgattttcag cgcttcaatg gacgccgcac gcgggtcttc
    14041 gtagtggtgc atctcgtgct caatcgcttc acgctctgcc gcactcagct caaaagcctc
    14101 ggtttgtggt tgttgattct cgtgcataat tagcggtcca catctgacat aacaaaatcg
    14161 atactgccca gataaacaat caggtcagac accaggctgc cgcggatcgc cgccggaatt
    14221 tgctgcaaat gcgcataact cggcgtgcgg atacgagtgc gataactcat ggtgctaccg
    14281 tcgctggtca ggtagtaact gttgatcccc ttggtcgcct caatcatctg gaaagattca
    14341 ttggcaggca tcaccggccc ccacgacact tgcaggaagt gggtgatcag ggtttcgata
    14401 tgttgcagcg tgcgctcttt cggcggcggc gtggtcagcg ggtgatccgc tttgaacggg
    14461 ccttccggca tgttgttgag gcactgctca agaatgcgca gactctggcg cagctcttcc
    14521 actttcagca ttacgcgggt gtagcagtca gaaacaccac caccaaccgg gatttcaaag
    14581 tcgaagtttt catagccaga ataaggacgc gccttacgca cgtcgaagtc gatcccggta
    14641 gcacgcaggc ccgcgccagt ggtgccccac tccagcgcct ctttcgcgcc ataggcggca
    14701 acgccctggg aacgaccttt cagaatggta ttttgcagcg ccgctttctc gtaagacgcc
    14761 agacgtttcg gcatccagtc gaggaactca cgcagcaggc gatcccagcc gcgcggcagg
    14821 tcgtgcgcta cgccgccaat acggaaccac gccgggtgca tacggaaacc cgtgatcgct
    14881 tccaccagat cgtaaatttt ctgacgatcg gtaaaggcga agaacacggg cgtcattgcg
    14941 ccgacgtcct gaataaaggt cgagatgtac agcaggtggc tgttgatacg gaacagttcg
    15001 gagagcataa cgcgaatgac gttaacgcga tccggcacgg tgatcccggc cagtttctct
    15061 accgccagca cgtaaggcat ttcgttaacg cagccgccga ggtattcaat acggtcggta
    15121 tacggaatgt agctgtgcca ggactggcgc tcgcccattt tctccgcacc acggtggtgg
    15181 tagccgatgt ctggtacgca gtcgacaatc tcttcgccgt cgagttgtaa aacgatacgg
    15241 aaagccccgt gcgccgacgg gtggttcgga ccgaggttga ggaacatgaa gtcctcgttt
    15301 tcggtgccgc gcttcatccc ccactcttcc ggtttgaagg tcagggcttc catctccaga
    15361 tcctgtttgg ctttggtcag ctcaaacggc gagaattcgg tagcgcgcgc cgggtaatct
    15421 ttacgcagcg ggtgaccttt ccaggtttgc ggcatcatga tgcggcgcag gttcgggtga
    15481 ccgtcgaaag taatgccaaa cagatcccag gtttcacgct cataccagtt agcattcggg
    15541 aacagtttgg tgaaggtcgg tacgtgcagg tcgttttctg ccagcgccac cttcagcatg
    15601 atgtcgcggt tacgatcgat agaaatcaga tggtagaaaa cggaaaaatc cgcggcaggt
    15661 aacccttcgc ggtgtgtgcg cagacgttcg tccatgccgt gtaagtcaaa cagcatgacg
    15721 taaggtttcg gcagtttctt taagaaatcg ccaacttcca gtaattgttc acgcttgatc
    15781 cacacaacgg gaaccccggt gcgagtcgcc tgaacagtaa aggcatccgg cccaaaacgg
    15841 ttgcgcagtt cgccaattac cggatcatca agatgatcgc gggtctgcca ggcgggttct
    15901 tgcgcggtta agtcggtcat attgttcacc attgcaaatg gtccgtggtg actgtcggcg
    15961 cagtaagctt cgcgaaatag atttaggaat aagcgaagaa aaatcccttt gccgacaggc
    16021 gcaaattaaa tctcgtcagg tgtacgcagg ttggttacgg caatacgttc accgcgcttg
    16081 cgttcgcgct ctgattgcat attggcgcga taaacgccct gatcgccaac cacccaggag
    16141 agcggacgac gttctttgcc gatagattcc tgcaacagca tcagtgcctg catgtacgct
    16201 tcaggacgcg gcgggcagcc cgggatatac acatcaaccg ggatgaattt atcgacgccc
    16261 tgcacaacgg aataaatatc gtacatacca ccagagttgg cacaggcacc cattgagata
    16321 acccattttg gttccagcat ctggtcatac agacgctgaa taaccggtgc cattttggta
    16381 aagcaggttc ctgcaaccac catcaggtca gcctgacgcg gcgaagcacg caatacttct
    16441 gcgccaaaac gcgccacgtc atgcaccgcg gtaaacgaag tcaccatctc aacgtaacag
    16501 caggaaagac cgaagttata cggccaaatt gagtttttac gaccccagtt aaccatgtca
    16561 ttgagcttgc ccataaacac gtttttgtta acttcttgct ccagagggtc ggttacgatc
    16621 tcctgctttt gcagggggta acggtcgttc tcaccgttgg gatctatgcg ggtgagcgta
    16681 taatccatct taatgcctcg cggttagcgt tgacgattag cgatactgtt cgtttccggg
    16741 ttcatacgct cgcggcgtga acgcgcgggc gtccagtcca gcgcgccaat acgcaccaga
    16801 taaaccagac ctgccagtaa cacaaaaata aaaattgcag cttccacaaa gcctacccag
    16861 ccgctttcgc ggatagaggt tgaccatgcg aacagataca gcgcttcaac gtcgaagata
    16921 acgaagaaca tggccaccag ataaaacttg gcggacaggc gtaagcgggc ggagccgacc
    16981 gagtcgatac cggattcaaa cggcacgttt ttcgacctcg cgcgtgcgcg accgcctaaa
    17041 aaccaaccgc ctaccagcat caggcaacac aggccaatgg caacgataag aaagatagcg
    17101 aatgcccagt gatgagcgat gacttcagtg gatgttgaca tactcattgc ttactcatca
    17161 aaagtagcgc cagattcact gctcttcacg gcagatggac gccacatcga ttcatgggga
    17221 ggaataaaaa aaaccttaca atcactgtag aaattctttt atacagctaa ttgatgtggt
    17281 cttttactcc tttctataac cttttgtcaa ctttaacaaa agtttcttca cattagttta
    17341 cataatatca acaccattag catttaatgc cctttcaccc cagatccttg acgactccag
    17401 gataattaga tgttgttgaa tcgtgtccgt tgtgaagcaa tggaaaaaat acgggtctat
    17461 tttgacagga atttgtgtcg attcctcccc ccaaaagaga gtattttctt gatctgtgac
    17521 acgcttttgt cattccataa caaaaacgca gcaacaaatt tacgtatttt ttaacatcat
    17581 tgtagcaggt gatttttttc aggcgattat ttgtgcgttc gggacgtgaa tctctggtga
    17641 ttgaaaaatg aacagttttg tacgttctgt actatgcgag gaaggatttt tactaaaaaa
    17701 aagccgctgg ggtttaaaac acccccagcg gctcgttttt tacactattg tctcaggaat
    17761 tatctatcgt ccgtcgatta ctcgatatcc ctttcaatca acaatgaatc atccccttcc
    17821 ggagcagaca ttgggctgta ttgccacgga ttatggtagc tctccatcgc ctgatagatc
    17881 acctgggcca gctcattatt actggacggg tcatagcaca gcaaatattc ggtatcaggt
    17941 agcggcggta agccatctac tccactcagc acacgcaggt ccgggctcat catctcaacc
    18001 ggccttgccg tcacgccaag accggctttc actgccgcac gaacggccgg aagcgtcgag
    18061 gcgacataag ccagtcgcca tggaatatct gctttattaa gcgtcgccag caccatatcg
    18121 cgaaacggac ttggatcatc cagcaataca agagggatcg gctcgccttt ttgcaatacg
    18181 tattccgctg cgcagtacca gtgtgttggc gaggttcgca ggttcaatgc cttaaacgct
    18241 gaaggacgat gggtggttac catcaaatcc acttcctggg attccagcat ttctgccata
    18301 taggcattac gtttaacgcg gacatccagc gctaatttcg gataaaccga actcacgcga
    18361 tttaacagga aaggtaagat cgtatcggca gattcatctg aagcaccgat agttaacacg
    18421 ccctgaagat tactgaacat taatgatgag caggcctcat cattaaaacg caggattttc
    18481 ctggcgtaac caagaagttg aatgccatgt tcagttaaca gtttgttgcg accgtgacga
    18541 gcgaacagtt ctttcccaac gagttgttcc agacgctgca tttgctgact tacggcggac
    18601 tgagtacgac acacagcggc agctgcggca gcaaaagtgt tcagatcggc aacagcaaca
    18661 aatgttctca gcagatcgag gtcgaggtta attatcggac gatttgcagt tatcatatat
    18721 tatcacttac tggcggctca tactgagctg gttaatgctg tgcacacaca aacaagcaat
    18781 tccatttgta atgtgcctcc ctggcagttt catccggaac ccggacgaaa gtaaaaatgc
    18841 atatgagttg cactaaaaaa gcgactcaca ttgttccgtt ataatgcctg aagtagatca
    18901 cagaatatat cttcagggat cgcatatcta ttaagttact cactcttttc tatttatgac
    18961 atgcgcgtgt ttgtataaat gtaaatgtga gtccttgttc cactctcgtg cagcatcgct
    19021 ggtcatacgc gaacacgtac aaacagcaat ggtgaggcgg catcaagagc agggatccgt
    19081 catttatgcg agcattttac cccaaaaacc ttttatttat aagggtcatt gcgaattatc
    19141 tgatgcaaag ttatgttatg ttaggcaaag taatcttcta t
//
LOCUS       DAPOAV010000082        19151 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.082, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000082 DAPOAV010000000
VERSION     DAPOAV010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19151
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.082"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..256)
                     /locus_tag="RN951_003379"
     CDS             complement(<1..256)
                     /locus_tag="RN951_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528332.1"
                     /translation="MSTENDEIINSLIRQINNFDKALQHAAARSDITLLAISFLASVM
                     DKNEVVRQSLVDYIDSLQPGTFNHESFNHEKEHVKSVINSL"
     gene            818..1006
                     /locus_tag="RN951_003380"
     CDS             818..1006
                     /locus_tag="RN951_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibition protein DicB"
                     /protein_id="HDX2528333.1"
                     /translation="MKTLLPNVNTSEGCFEIGVTISNPVFTEDAINKRKQERELLNKI
                     CILSMLARLRPIQKGCWQ"
     gene            1003..1194
                     /locus_tag="RN951_003381"
     CDS             1003..1194
                     /locus_tag="RN951_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1482 family protein"
                     /protein_id="HDX2528334.1"
                     /translation="MNTAFALVLTVFLVSGEPVDIAVSVHRTMQECVTAATEQKIPGN
                     CYPVDKVIHQDNNEIPAGL"
     gene            1287..3758
                     /locus_tag="RN951_003382"
     CDS             1287..3758
                     /locus_tag="RN951_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HDX2528335.1"
                     /translation="MSKVFICAAIPDEQAIKEEGAVAVATAIEAGDERRARAKFHWQF
                     LEHYPAAQDCAYKFLVCEDKPGIPRPALDSWDAEYMQENRWDEESASFVPVETESDPM
                     NVTFDKLAPEVQNAVMVKFDTCENITVDMVISAQELLQEDMATFDGHIVEALMKMPEV
                     NAMYPELKLHAIGWVKHKCKPGAKWPEIQAEMRIWKKRREGERKETGKYTSVVDLARA
                     RTNQQHSENSTGKISPVIAAIHREYKQTWKTLDDELAYALWPGDVDAGNIDGSIHRWA
                     KNEVIDNDREDWKRISASMRKQPDALRYDRQTIFGLVRERPIDIHKDPVALNKYITEY
                     LTTKGVFEDEGRNQSATDTLSSPVPETDAVETAIPGNEKTECKVEVEPSVEREGPFYF
                     LFTDKDGEKYGRANKLSGLEKALALGATEITKEEYFARKNGTYSGSQQNTGASDTTAQ
                     PEPVKVTADEVNKIMQAANISQPDADKLLAASRGEFVAGISDPNDPKWVKGIETRDSV
                     NQNQQESEQNDQKAEQNSPNTQQNEPETKQPEPVAQQEPEKVCTACGQSGGGNCPDCG
                     AVMGDATYQETFDEENQVEVQENDPKEMEGAEHPHKENAGSAQDHASDSETGETADPL
                     IAMNGHHVITSTSRTCDHLMIDLETMGKNPDAPIISIGAIFFDPQTGDMGPEFSKTID
                     LETAGGVIDRDVIKRWLKQSREAQSAIMTDEIPLDDALLQLREFIDENSGEFFVQVWG
                     NGANFDNTILRRSYERQGIPCPWRYYNDRDVRTIVELGKAIDFDARTAIPFEGERHNA
                     LDDARYQAKYISVIWQKLIPNQADF"
     gene            3823..4071
                     /locus_tag="RN951_003383"
     CDS             3823..4071
                     /locus_tag="RN951_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDX2528336.1"
                     /translation="MARLILLTEWAKEEFSEPVPTPSTLSKYAKAGMIFPLPKKVGRR
                     WRVDPQARFVGMVNKPEVIATDHPALKRILEDGAPAKI"
     gene            4049..5179
                     /locus_tag="RN951_003384"
     CDS             4049..5179
                     /locus_tag="RN951_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase Arm DNA-binding
                     domain-containing protein"
                     /protein_id="HDX2528337.1"
                     /translation="MARPRKYKTDVPGLSPYFDKRNNKVYWRYRHPITGKNHGLGSID
                     QKLAETIAAEANSRLARQQMEQMLSLQEKIISDTGGSSTVTIFLNNYRKIQQERYENG
                     EIKLNTLKQKAAPLRVFDERFGTRPLDAITVKDVVSVLEEYKARGHNRMGQIFRKVLI
                     DVFREAQQTGDVPPGFNPAESAKKPQVRISRQRLTFDEWMMIYNAAEKDGYFLQRGML
                     LALMTGQRLSDICKMQFSDIRDGYLHVEQQKTGTRIAIPLALRCDKLNLTLDDVVSSC
                     RDCVLSPWLLHHHHAKGTAKRGGMVKPATLTVAFKKARDSVDYNWRANGTPPSFHEQR
                     SLSERLFREQGVDTKILLGHSNQKMTDIYNDARGKEWKKLVI"
     gene            complement(5225..5863)
                     /gene="ompW"
                     /locus_tag="RN951_003385"
     CDS             complement(5225..5863)
                     /gene="ompW"
                     /locus_tag="RN951_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpW"
                     /protein_id="HDX2528338.1"
                     /translation="MKKLTVAALAVTTLLSGSAFAHEAGEFFMRAGSATVRPTEGAGG
                     TLGSLGGFSVTNNTQLGLTFTYMATDNIGVELLAATPFRHKIGTRATGDIATVHHLPP
                     TLMAQWYFGDASSKFRPYVGAGINYTTFFDNGFNDHGKEAGLSDLSLKDSWGAAGQVG
                     VDYLINRDWLVNMSVWYMDIDTTAKYKSGVTTVKDSVRLDPWVFMFSAGYRF"
     gene            6103..6192
                     /locus_tag="RN951_003386"
                     /pseudo
     CDS             6103..6192
                     /locus_tag="RN951_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460692.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
     gene            6220..6963
                     /locus_tag="RN951_003387"
     CDS             6220..6963
                     /locus_tag="RN951_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0259 family protein"
                     /protein_id="HDX2528339.1"
                     /translation="MSITAQSVYRDTGNFFRNQFMTILLVSLLCAFITVVLGHVFSPS
                     DAQLAQLNDGEPVSGSSGLFDLVQNMSPEQQQILLQASAASTFSGLIGNAILAGGVIL
                     IIQLVSAGQRVSALRAIGASAPILPKLFILIFLTTLLVQIGIMLVVVPGIIMAILLAL
                     APVMLVQDKMGVFASMRSSMRLTWANMRLVAPAVLSWLLAKTLLLLFASSFAALTPEI
                     GAVLANTLSNLISAILLIYLFRLYMLIRQ"
     gene            6993..7532
                     /locus_tag="RN951_003388"
     CDS             6993..7532
                     /locus_tag="RN951_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation protein A"
                     /protein_id="HDX2528340.1"
                     /translation="MKQFLDFLPLVVFFAFYKIYDIYAATAALIVATAIVLIYSWVRF
                     RKVEKMALITFVLVVVFGGLTLFFHNDEFIKWKVTVIYALFAGALLVSQWVMKKPLIQ
                     RMLGKELTLPQPVWSKLNLAWAVFFILCGLANIYIAFWLPQNIWVNFKVFGLTALTLI
                     FTLLSGIYIYRHMPQEDKS"
     gene            7637..8035
                     /gene="yciA"
                     /locus_tag="RN951_003389"
     CDS             7637..8035
                     /gene="yciA"
                     /locus_tag="RN951_003389"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioester hydrolase YciA"
                     /protein_id="HDX2528341.1"
                     /translation="MSTTHNVPQGDLVLRTLAMPADTNANGDIFGGWLMSQMDIGGAI
                     LAKEIAHGRVVTVRVEGMTFLRPVAVGDVVCCYARCVQKGTTSVSINIEVWVKKVASE
                     PIGQRYKATEALFKYVAVDPEGKPRALPVE"
     gene            complement(8075..8794)
                     /gene="tonB"
                     /locus_tag="RN951_003390"
     CDS             complement(8075..8794)
                     /gene="tonB"
                     /locus_tag="RN951_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein TonB"
                     /protein_id="HDX2528342.1"
                     /translation="MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQP
                     ISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKP
                     VKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQ
                     PQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPG
                     KPGSGIVVNILFKINGTTEIQ"
     gene            9018..9314
                     /locus_tag="RN951_003391"
     CDS             9018..9314
                     /locus_tag="RN951_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415767.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciI family protein"
                     /protein_id="HDX2528343.1"
                     /translation="MLYVIYAQDKADSLEKRLSVRPAHLARLQLLHDEGRLLTAGPMP
                     AVDSNDPGAAGFTGSTVIAEFESLEAAQAWADADPYVAAGVYEHVSVKPFKKVF"
     gene            9614..10867
                     /gene="kch"
                     /locus_tag="RN951_003392"
     CDS             9614..10867
                     /gene="kch"
                     /locus_tag="RN951_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated potassium channel protein"
                     /protein_id="HDX2528344.1"
                     /translation="MSHWATFKQTATNLWVTLRHDILALAVFLNGLLIFKTIYGMSVN
                     LLDIFHIKAFSELDLSLLANAPLFMLGVFLVLNSIGLLFRAKLAWAISIILLLIALIY
                     TLHFYPWLKFSIGFCIFTLVFLLILRKDFSHSSAAAGTIFAFISFTTLLFYSTYGALY
                     LSEGFNPRIESLMTAFYFSIETMSTVGYGDIVPVSESARLFTISVIISGITVFATSMT
                     SIFGPLIRGGFNKLVKGNNHTMHRKDHFIVCGHSILAINTILQLNQRGQNVTVISNLP
                     EDDIKQLEQRLGDNADVIPGDSNDSSVLKKAGIDRCRAILALSDNDADNAFVVLSAKD
                     MSSDVKTVLAVSDSKNLNKIKMVHPDIILSPQLFGSEILARVLNGEEINNDMLVSMLL
                     NSGHGIFSDNDELETKADSKESAQK"
     gene            complement(10922..11095)
                     /locus_tag="RN951_003393"
     CDS             complement(10922..11095)
                     /locus_tag="RN951_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciY family protein"
                     /protein_id="HDX2528345.1"
                     /translation="MKRSRTEVGRWRMQRQASRRKSRWLEGQSRRNMRIHSIRKCILN
                     KQRNSLLFAIYNI"
     gene            11238..12698
                     /gene="cls"
                     /locus_tag="RN951_003394"
     CDS             11238..12698
                     /gene="cls"
                     /locus_tag="RN951_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDX2528346.1"
                     /translation="MTTVYTLVSWLAILGYWLLIAGVTLRILMKRRAVPSAMAWLLII
                     YILPLVGIIAYLAVGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAEENSSVAAP
                     LFKLCERRQGIAGVKGNQLQLMTESDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQ
                     VAESLMAAARRGIHCRLMLDSAGSVAFFRSPWPELMRNAGIEVVEALKVNLMRVFLRR
                     MDLRQHRKMIMIDNYIAYTGSMNMVDPRYFKQDAGVGQWIDLMARMEGPIATAMGIIY
                     SCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTAAYSAR
                     EYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSMLVGWASRAFFTELLAAG
                     VKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLAIDDKGFGADLAAVQ
                     DDYISRSRLLDARLWLKRPLWQRVAERLFYFFSPLL"
     gene            12733..13062
                     /locus_tag="RN951_003395"
     CDS             12733..13062
                     /locus_tag="RN951_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309775.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciU family protein"
                     /protein_id="HDX2528347.1"
                     /translation="MDMDLNNRLTEDETLEQAYDIFLELAADNLDPADVLLFNLQFEE
                     RGGAELFDPAEDWQEHVDFDLNPDFFAEVVIGLADSEDGEINDVFARILLCREKDHKL
                     CHIIWRE"
     gene            complement(13115..14119)
                     /gene="oppF"
                     /locus_tag="RN951_003396"
     CDS             complement(13115..14119)
                     /gene="oppF"
                     /locus_tag="RN951_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide/oligopeptide ABC transporter
                     ATP binding protein OppF"
                     /protein_id="HDX2528348.1"
                     /translation="MNAVTEGRKVLLEIADLKVHFEIKDGKQWFWQPPKTLKAVDGVT
                     LRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGHVAWLGKELLGMKPDEWRAVRSD
                     IQMIFQDPLASLNPRMTIGEIIAEPLRTYHPKMSRQEVRERVKAMMLKVGLLPNLINR
                     YPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSL
                     IFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNPLHPYTRALMSAVPIPDPDLE
                     KNKTIQLLEGELPSPINPPSGCVFRTRCPIAGPECAKTRPVLEGSFRHAVSCLKVDPL
                     "
     gene            complement(14116..15129)
                     /gene="oppD"
                     /locus_tag="RN951_003397"
     CDS             complement(14116..15129)
                     /gene="oppD"
                     /locus_tag="RN951_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide/oligopeptide ABC transporter
                     ATP binding protein OppD"
                     /protein_id="HDX2528349.1"
                     /translation="MSVIETATVPLAQQQADALLNVKDLRVTFSTPDGDVTAVNDLNF
                     SLRAGETLGIVGESGSGKSQTAFALMGLLAANGRIGGSATFNGREILNLPEHELNKLR
                     AEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKNMSKAEAFEESVRMLDAVKMPEARK
                     RMKMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREF
                     NTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDVFYQPVHPYSIGLLNAVPRLD
                     AEGETMLTIPGNPPNLLRLPKGCPFQPRCPHAMEICSSAPPLEEFTPGRLRACFKPVE
                     ELL"
     gene            complement(15141..16049)
                     /gene="oppC"
                     /locus_tag="RN951_003398"
     CDS             complement(15141..16049)
                     /gene="oppC"
                     /locus_tag="RN951_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HDX2528350.1"
                     /translation="MMLSKKNSETLENFSEKLEVEGRSLWQDARRRFMHNRAAVASLI
                     VLVLIALFVILAPMLSQFAYDDTDWAMMSSAPDMESGHYFGTDSSGRDLLVRVAIGGR
                     ISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFF
                     GQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTSGIVIRHIVPNV
                     LGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPA
                     GFLVVTLFCFNFIGDGLRDALDPKDR"
     gene            complement(16064..16984)
                     /gene="oppB"
                     /locus_tag="RN951_003399"
     CDS             complement(16064..16984)
                     /gene="oppB"
                     /locus_tag="RN951_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppB"
                     /protein_id="HDX2528351.1"
                     /translation="MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGERTLPPE
                     VMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFKYKDYSVNDLVASSFPVSAKLGA
                     AAFFLAVILGVSAGVIAALKQNTKWDYTVMGLAMTGVVIPSFVVAPLLVMIFAIILHW
                     LPGGGWNGGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRR
                     IILRHALKPALLPVLSYMGPAFVGIITGSMVIETIYGLPGIGQLFVNGALNRDYSLVL
                     SLTILVGALTILFNAIVDVLYAVIDPKIRY"
     gene            complement(17070..18701)
                     /gene="oppA"
                     /locus_tag="RN951_003400"
     CDS             complement(17070..18701)
                     /gene="oppA"
                     /locus_tag="RN951_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707150.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein OppA"
                     /protein_id="HDX2528352.1"
                     /translation="MTNITKRSLVAAGVLAALMAGNVALAADVPAGVTLAEKQTLVRN
                     NGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWDNKDAKVWTFHL
                     RKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDL
                     GVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYT
                     LKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTYNNMPI
                     ELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKA
                     QGDMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLTINLLYN
                     TSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPT
                     SFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPV
                     YYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH"
BASE COUNT         5039 a         4602 c         4565 g         4945 t
ORIGIN      
        1 taagagaatt aattacagac ttaacatgct ctttctcatg attgaagctc tcatgattga
       61 aagtgccggg ttgaagcgag tcgatataat caacaagact ctgtcgtacg acttcatttt
      121 tatccataac agatgcaaga aatgaaattg ctaaaagagt tatatcacta cgcgccgcag
      181 catgttgcaa tgctttatca aaattattaa tctggcgtat cagggagtta atgatttcat
      241 cattttcagt cgacatttca ccctcctgag ggttggtgat taaggagttc tccacgggtg
      301 aggtggagtg cgtgcgccgg acacgggtga gcatccggca ctgacagttt actgaaagga
      361 tatttccctg aaaagtcaga ccataacgcg aaagcgcccg gcgaggtagc tggttcatag
      421 atagcctgtc gttaaatttt cgtcgaccgt gcgtttccgg ttgtggcaat ccgcgaaatg
      481 gcgcggcggt aagtatggcg gggttattcc ttccccgttg aggacaccgg gttgtcaggt
      541 tgaccatacg cttaagtgac aaccccgctg caacgccctc tgttatcaat tttctggtga
      601 cgtttggcgg tatcagtttt actccgtgac tgctctgccg ccctttttaa agtgaatttt
      661 gtgatgtggt gaatgcggct gagcgcacgc ggaacagtta aaaccaaaaa cagtgttatg
      721 ggtggattct ctgtatccgg cgttaattgt taactagtta acgtcacctg gaggcaccag
      781 gcactgcatc acaaaattca ttgttgagga cgcgataatg aaaacgttat taccaaacgt
      841 taatacgtct gaaggttgtt ttgaaattgg tgtcactatc agtaacccag tatttactga
      901 agatgccatt aacaagagaa aacaagaacg ggagctatta aataaaatat gcattctttc
      961 aatgctggcc cgtttacgtc cgatacaaaa aggatgctgg caatgaatac agcatttgca
     1021 cttgttctga cagtttttct tgtttccgga gagccagttg atattgcagt cagtgttcac
     1081 aggacaatgc aggagtgtgt gactgcagca accgaacaga aaattcccgg taactgttac
     1141 ccggtcgata aagttattca ccaggataat aacgaaatcc cggcaggtct ttaaaacagt
     1201 tccgtaataa atatccggtt tcattcttat atgccagcaa tggcagggat ttgttcaccc
     1261 ttaaatctgt aatgaggtaa aacaaaatga gtaaagtctt tatttgcgcc gccattccgg
     1321 acgaacaggc aataaaggaa gaaggtgccg tcgctgtagc cactgccatt gaagccggtg
     1381 atgaacgtcg cgcccgcgca aaatttcact ggcaattcct ggaacattat ccggctgctc
     1441 aggactgcgc ttataaattt cttgtctgcg aggataaacc cggtataccc cgccctgccc
     1501 tcgattcctg ggatgctgaa tatatgcagg aaaaccgctg ggatgaggag tctgcttcct
     1561 ttgtcccggt tgagactgaa tcagatccga tgaacgtcac ttttgacaag ctggcccctg
     1621 aagtacagaa cgctgtcatg gttaagttcg acacatgtga aaacatcacc gttgatatgg
     1681 ttattagcgc acaggaattg ttgcaggaag acatggcaac attcgacgga catatcgttg
     1741 aagcgttgat gaaaatgcca gaagttaacg ccatgtatcc ggagcttaag ctgcatgcca
     1801 tcgggtgggt taagcataaa tgtaagcctg gtgccaaatg gcccgaaatt caggcagaga
     1861 tgcgcatctg gaaaaaacgt cgcgaaggtg aacgcaagga aaccggaaaa tacacgtctg
     1921 ttgttgatct cgcccgcgcc agaaccaatc aacagcacag tgaaaattca acaggaaaaa
     1981 tcagcccggt cattgctgcc attcatcgcg aatacaagca gacatggaaa acactggatg
     2041 acgaactggc ctacgctctc tggcctggtg atgtggatgc cggaaacatt gacggcagca
     2101 tccatcgctg ggcaaaaaat gaagttatcg acaacgaccg cgaagactgg aagcgtatct
     2161 cggcatcaat gcgcaaacag cctgatgccc ttcgctacga ccgccagact atttttggcc
     2221 ttgtccgtga acgtccgatc gacattcaca aagaccctgt ggcactgaac aaatacatta
     2281 ctgaatacct gactacaaag ggcgtgtttg aagatgaagg aagaaatcag agcgcaactg
     2341 atactctctc gtcgccagta ccagaaactg atgcagtgga aacggcaatt ccgggcaacg
     2401 aaaaaaccga atgcaaagtg gaagtcgaac catctgtaga gcgtgagggg ccgttctact
     2461 tcctcttcac cgacaaggat ggcgaaaaat acggtcgcgc aaacaaactt tctggtctgg
     2521 aaaaagcact agccttggga gctacggaaa tcacaaaaga ggaatacttc gcacgtaaaa
     2581 acggcacgta ctcaggttca caacaaaata ctggtgcatc tgacacgacc gcacaaccag
     2641 agccggtaaa agttaccgct gacgaagtaa acaaaattat gcaggcagcc aatatcagcc
     2701 agcctgacgc cgataagttg cttgctgcct ctcgcggaga atttgttgca gggattagcg
     2761 acccgaatga tccgaaatgg gtaaagggga ttgaaacccg cgattctgta aaccagaacc
     2821 agcaagaatc ggaacagaac gaccagaaag cggaacaaaa cagcccaaat acgcaacaaa
     2881 acgagccaga aacgaaacaa cctgagccag tagcgcaaca ggaaccggaa aaagtctgca
     2941 ccgcctgcgg tcaaagcggt ggcggcaact gccctgattg tggcgcggtg atgggtgacg
     3001 caacatacca ggaaacattc gatgaagaga atcaggttga agttcaggaa aatgatccga
     3061 aggaaatgga aggcgctgaa catccacaca aggagaatgc tggtagcgct caggatcacg
     3121 ccagcgatag tgaaactggc gagacggcag atcccttaat tgcgatgaac ggtcatcacg
     3181 ttatcacatc caccagcagg acgtgtgacc atctaatgat cgaccttgaa accatgggaa
     3241 aaaatcctga tgccccgatt atctcaatag gtgcaatatt tttcgatccg caaaccggag
     3301 atatgggacc ggaatttagt aagactatcg atctggaaac tgctggcgga gtcattgatc
     3361 gtgacgtcat taaaaggtgg ctgaagcaat cacgtgaagc gcagtctgcc attatgaccg
     3421 atgaaatccc gttagatgat gcactgttac aattgcggga atttatcgac gaaaactccg
     3481 gtgaattttt tgttcaggtc tggggaaatg gagccaactt cgacaacacg attttgcgcc
     3541 gttcatacga acggcagggg atcccctgcc cgtggcgtta ctacaacgat cgcgatgtac
     3601 gcacaatcgt tgagctgggg aaagccatag acttcgatgc cagaacggct attccattcg
     3661 aaggtgagcg ccataatgca cttgatgacg cccgttacca ggcaaaatac atttcagtta
     3721 tctggcaaaa actgatcccg aatcaggctg atttttaatg ttcaaccccg gtcgttgccc
     3781 accagctata gtggcggcga ccatgattag cgaacgacgc tcatggcaag acttattctg
     3841 ctcactgagt gggcaaaaga ggaattcagt gaaccggtcc ctactccgag tacgttaagt
     3901 aaatacgcta aagccggaat gatatttcct ctccccaaaa aagttggaag acgctggcga
     3961 gtggatccgc aagctcgctt tgtcggaatg gtaaacaagc cggaggtgat cgccacagat
     4021 caccctgctt tgaagaggat actggaagat ggcgcgcccg cgaaaatata aaaccgatgt
     4081 tccgggatta tctccgtatt ttgacaaaag aaataacaaa gtttactggc gttacaggca
     4141 tcccataaca ggcaaaaatc acggtctcgg cagtattgac cagaaactgg cagaaactat
     4201 tgcagcagaa gcgaacagcc gtcttgcccg gcagcaaatg gaacaaatgc tcagtctgca
     4261 ggagaaaatt attagtgata ccggcggttc atcaaccgtt accatttttc tgaataatta
     4321 cagaaaaatt caacaggaaa gatatgaaaa cggcgagatc aaactcaaca cgctgaaaca
     4381 gaaagcggcc cctctcaggg tatttgatga acgttttggc accagaccgt tagatgccat
     4441 aaccgtaaaa gatgtggtat cagtactgga agagtacaag gccagaggac ataacagaat
     4501 gggacaaatt ttcaggaaag tactgatcga tgttttccgg gaagctcagc aaacgggcga
     4561 tgtcccgcca ggctttaacc ctgcagaatc ggcaaaaaaa ccgcaggtgc ggatatcaag
     4621 acagcgactg acttttgatg agtggatgat gatttataac gcagcggaaa aggatggtta
     4681 ctttttacag cgcggtatgc tgctggcact gatgacaggc cagcgccttt cagatatttg
     4741 caaaatgcaa ttttcggata tccgggatgg ttatcttcat gtcgaacagc aaaaaacagg
     4801 aacccggatt gccatccctc tggctctgcg ttgcgataaa ttaaatctca ccctggatga
     4861 tgtggtgtca tcctgccgcg attgcgttct tagtccgtgg ctattgcacc accatcacgc
     4921 gaaagggaca gctaagcgcg gcgggatggt taagccagca acattaaccg ttgcatttaa
     4981 aaaagcccgg gattctgtgg attacaactg gcgtgctaat ggcacccctc cctctttcca
     5041 tgagcagaga tctttatcag agcgattgtt cagagagcag ggggttgata ccaaaatttt
     5101 gctaggccat tcgaatcaaa aaatgaccga tatttacaac gacgcacgcg gtaaggaatg
     5161 gaaaaaactg gtcatttgat gaccagtttt gcagaggggt tttgcagagg ttttgcagag
     5221 aaaattaaaa acgatatcct gcggagaaca taaacaccca cggatccagt cgtaccgagt
     5281 cttttacggt agtaacacca gatttgtact tagccgtggt atcgatatcc atgtaccaca
     5341 ctgacatgtt aaccaaccag tcacggttaa tcagataatc aacccccacc tgcccggcag
     5401 ctccccagga atctttcaga ctgagatcgg aaagccctgc ctctttgcca tgatcgttaa
     5461 atccattatc aaagaaggtg gtgtagttaa tacctgcccc aacgtaagga cggaatttgc
     5521 tgctggcatc accaaaatac cactgcgcca tcagtgttgg tggcagatga tgaacggttg
     5581 caatatcgcc ggtcgcccgg gtgccgattt tatggcggaa cggcgtcgct gccagtaatt
     5641 ccacaccaat gttgtcggtc gccatataag taaacgtaag gcccagttgc gtgttattgg
     5701 tcacgctgaa tccacccaga cttcctaacg taccaccagc accttctgtt ggacgtacgg
     5761 ttgcagaacc tgcacgcata aaaaattcgc ctgcttcatg cgcaaaggca ctgccagaga
     5821 gaagagttgt tactgccaaa gccgccactg ttaacttttt catatccgct ccgtcgttat
     5881 ggttataaaa acgtgacgaa tatacctaca ttggagtaac aaatgatcct acatagatca
     5941 cattacatat gataattcac cctttattga tctggattaa tttagaagtt gcattgagaa
     6001 tcctggttaa tgtgatttaa atcaattttt aaatattttc gctacgcaaa tattaactcg
     6061 gtcgccactt gccgcgattt gcccatgcct gaaggccagc aattacctcc gctttacaaa
     6121 gatatgcttt tccatacaag acctgatgct gccacccgag gcttaaccag ggtacaattg
     6181 cccgctaatt aacacctgca taaaactcaa ggagagtgca tgtctatcac ggcgcagtcc
     6241 gtataccgtg acaccggaaa tttcttccgt aatcaattta tgaccattct gttggtatcg
     6301 ttgctatgtg cgtttatcac agtggtgtta gggcatgttt tctcacccag tgatgcacag
     6361 cttgcgcagc tcaatgacgg cgagcccgtt agcggcagta gtgggttgtt cgacctggtt
     6421 cagaatatgt caccggaaca gcaacaaatt ttgctgcagg cttcagcggc gtccactttt
     6481 tcaggattaa tcggtaacgc cattctcgcc ggaggcgtaa tattaattat ccagctggtg
     6541 tctgcgggtc agagagtcag tgcgctgcga gctattggtg ccagtgcgcc gatattgcca
     6601 aagttattta ttctgatttt tctgactacc cttttagtac agattggcat catgctggtg
     6661 gtcgttccgg gaattatcat ggccatttta ctggccctgg caccggtgat gttggtacag
     6721 gacaaaatgg gcgtttttgc ctcgatgcgt agcagtatgc ggctgacttg ggcgaatatg
     6781 cgtctggtgg cacccgcagt actgagctgg ttgctggcaa aaacactgtt gctgcttttt
     6841 gcctcttctt ttgccgcatt aaccccggaa attggtgccg tactggcgaa caccttgagc
     6901 aacctgattt cagccatatt gctcatctat ctgttccgcc tgtatatgtt gattcgccaa
     6961 taaccttaag catttgatta cggaatcgta aaatgaagca gtttcttgat tttttaccgc
     7021 tggttgtctt tttcgcgttt tacaagattt atgacatcta tgcggctact gcggcgctga
     7081 tcgtcgccac ggcgattgtg cttatctata gctgggttcg ctttcgtaag gttgagaaga
     7141 tggccctgat cacttttgtt ctggtggtcg tcttcggtgg cttgacgctg ttcttccaca
     7201 atgatgagtt tattaaatgg aaggttacag tcatttatgc tctatttgcg ggagccctgt
     7261 tagtcagcca atgggtgatg aaaaagccgc taattcagcg gatgctgggt aaagaactca
     7321 cgctgccgca accggtatgg tcgaagctga atctggcctg ggctgttttc tttatccttt
     7381 gcggtctggc aaacatctac atcgcattct ggctgccgca aaatatttgg gtcaacttta
     7441 aagtctttgg cctgaccgcc cttaccttaa tcttcacatt gttaagcggt atctatatct
     7501 accgccacat gccgcaggaa gataaatcct aaccagactg ccagtccttc ggggctggcg
     7561 ctgtatctcc tctgttctcc tcaggaaaat catagtagca tcgcgcctgt gattttcctt
     7621 ttaagtcggt tttaccatgt ctacaacaca taacgtccct cagggcgatc ttgttttacg
     7681 tactttagcc atgcccgccg ataccaatgc caatggtgac atctttggtg gttggttaat
     7741 gtcacaaatg gatattggcg gcgctattct ggcaaaagaa attgcccacg gtcgcgtagt
     7801 gactgtgcgg gttgaaggaa tgactttctt acggccggtt gcggtcggcg atgtggtgtg
     7861 ctgctatgca cgctgtgtcc agaaagggac gacatcggtc agcattaata ttgaagtgtg
     7921 ggtgaaaaaa gtagcgtctg aaccaattgg gcaacgctat aaagcgacag aagcattatt
     7981 taagtatgtc gcggttgatc ctgaaggaaa acctcgcgcc ttacctgttg agtaatagtc
     8041 aaaagcctcc ggtcggaggc ttttgacttt ctgcttactg aatttcggtg gtgccgttaa
     8101 ttttaaacag gatattcacc acaatcccac tgcctggctt acccggctca taacgccatc
     8161 tgcgcatcgc atttttcacc tcacgctcaa acatgttcgc aggcttggct gagaggattt
     8221 gtacgttatc cacgcgacca tccggcgtaa cgtcaaattt aactttaacc tgcccttcaa
     8281 tgcgcaatgc ctgtgctcgt gccggatact gcggctgatt acggcttaat gcgcgtggtc
     8341 ctgaagccac actggtaacc ggcttgctgg ttgcagccgt tgctgtactt gatgtcaggc
     8401 gtgccggtgc cgtattttca aacggtgatg ccggacgcga ctctacgggt ttgacatcgc
     8461 gttttggctg ctcctgtacc tttttcaccg gcttcggttt tggcttaggt ttcggcttcg
     8521 gcttttcaat gaccaccggt gcttcttttg gcggttcggg gatcggctca ggttccggtt
     8581 ctggctctac caccggctcc ggtggcggct gaacggcttg tggcggttcg agatcagcag
     8641 gcgtaaccat cgtgacagaa atcggctgcg caggcgcagg tagttcaata acctgatgta
     8701 ccgaggtata gagcagaccc gccacaacag caccatgaat gcagaccgaa agtaacgtcg
     8761 gccaggggaa gcggcgaggt aaatcaaggg tcattgaagt cataatcatt tcagtagaaa
     8821 aaccaggtct cgattttaaa tgcaaatagc aatcatattc aataaggcaa gacgatcagg
     8881 atcagtgaaa atgtcatttt tggcgtaatt acccttactt tatgcatggc cttaacaaag
     8941 acatcatctt tccgttgcag atcttcgccc tttcaaataa cgtactttac aactttcccg
     9001 aacaaggagt tgtgcccgtg ttgtatgtta tttacgctca agacaaagct gatagcctcg
     9061 aaaaacgcct ttccgttcgt ccggcacatt tagcacgttt acagttactg catgatgaag
     9121 gtcgtttgtt gacagctggt ccaatgccag cggtagacag taacgatcca ggggctgcgg
     9181 gatttactgg ctcaaccgtt attgctgaat ttgaatcgct ggaagcagct caggcctggg
     9241 ccgatgctga cccgtacgta gcggcaggag tctatgaaca cgtttcagtg aaaccattta
     9301 agaaagtgtt ctgaatagag attcaatatt taagggcacg gtttttgcaa ccgtgttctt
     9361 gtttggcctt tccttatagc cggtcagtgc attcaccacc acaagcagat aataacttta
     9421 tctgtatttc tttatatgat gtgagcatat tcaggaaaaa tgacctttcc tgaggtacag
     9481 ttgctcgctc aaatcctttg attactgcgg ataaagtcat ctactattgt ttaacacatt
     9541 cacgcgctgc atgtatgttc agaaaatgtg cacgctaaga taattaaaca aaattgtggt
     9601 tacagaggta tcagtgagtc actgggctac attcaaacaa acagcaacaa atttatgggt
     9661 gacccttcgg cacgacattc tcgcgctggc cgtcttttta aatggattgc ttatttttaa
     9721 aacaatctat ggtatgtcgg tcaatttgct tgatattttc catatcaaag cattttcaga
     9781 gttggatctc tccttgctgg caaacgcccc actctttatg ctcggcgtct ttcttgtcct
     9841 gaactccatt ggcttactgt tccgggcaaa gctcgcatgg gcaatcagta tcattttgtt
     9901 gttgatagcg ctaatttaca ccctgcattt ttatccctgg ctgaaattta gtattggatt
     9961 ttgcattttt acgctggtgt ttttgctgat actgcgcaaa gacttctccc acagtagcgc
    10021 cgcagccggg acaatttttg catttattag tttcacgaca ttactgtttt actcaaccta
    10081 cggtgcgctt tatttaagcg aaggttttaa tccgcgaata gaaagtttga tgaccgcgtt
    10141 ctatttttcg atagaaacca tgtcaaccgt cggctatggc gatattgtcc ctgtttctga
    10201 atcagcacga ttgttcacta tttcggtcat tatttccggc attaccgttt ttgccacatc
    10261 tatgacctca atttttggtc cgcttatccg cgggggattc aacaaacttg taaaaggaaa
    10321 caatcataca atgcatcgta aagatcattt tattgtttgc ggacattcga ttctcgccat
    10381 caatacgatc ctgcaactga atcaacgcgg acaaaacgta acggttatca gcaacttgcc
    10441 tgaagatgat atcaagcaac ttgagcaacg cttaggcgat aatgctgatg ttatccccgg
    10501 tgacagtaat gacagttctg tattaaagaa agcgggaatc gatcgttgcc gggccattct
    10561 ggcgctgagt gataacgatg cagataacgc gtttgttgta ctctcggcaa aagatatgag
    10621 cagtgatgtc aaaacagttc tcgccgtcag tgatagcaaa aacctgaata agattaagat
    10681 ggtacatccg gatatcattc tctcaccgca actgtttggc agcgaaattc tggcgcgagt
    10741 tttaaatggt gaagagatta ataatgatat gctcgtttca atgttgttga actcaggtca
    10801 tggtattttc agcgataacg atgaactaga aacgaaagct gacagtaaag aatcggcgca
    10861 aaaatagagt ttaaagacgg aagagtaaac ttattgggca ccgcaatggt gcccagtaca
    10921 tttagatatt gtagatcgca aacaataacg agttacgctg tttgtttaga atgcacttcc
    10981 tgatgctgtg gatacgcata tttcggcgcg attgcccctc aagccaacgc gatttacgtc
    11041 ggctagcctg acgctgcatg cgccagcgcc ccacttccgt tctactccgc ttcatgttaa
    11101 ctactctatg caataacaga atggtcatta tacctccacc cccgacgctg accagtgctt
    11161 ttcccgcgtt tttatttgcc agatgaatcc atatgcgtaa actcataaca atgcgctttc
    11221 aaaaggattt ctaatctatg acaaccgttt atacgttggt gagttggttg gccattctgg
    11281 gatactggtt gctcattgca ggcgtaactt tacgcattct aatgaaacga cgcgcagttc
    11341 cctccgcgat ggcctggctg ttgattattt acattctgcc gttagtcgga attattgcct
    11401 atcttgccgt tggcgagctc catttaggca aacgccgcgc tgagcgcgcc agagcgatgt
    11461 ggccttccac cgcaaaatgg cttaacgacc ttaaagcctg taagcatatc ttcgccgaag
    11521 aaaatagcag tgtcgctgcg ccattattca agctttgcga gcgtcgtcag gggatcgctg
    11581 gggtcaaagg gaatcagcta caactgatga ccgagtcaga tgatgtgatg caggcgttaa
    11641 tccgcgacat ccagctcgcg cgccataata ttgagatggt gttttatatc tggcagcccg
    11701 gcggcatggc ggaccaggtg gctgaatcat taatggcggc tgcgcgacgc ggcattcatt
    11761 gccgattgat gctcgactcc gccgggagtg tggctttttt ccgcagcccg tggcccgagc
    11821 taatgcgtaa tgccggtatt gaagtggtcg aagccttaaa ggtcaatctg atgcgtgtgt
    11881 ttttacgccg tatggacctg cgccaacatc gcaagatgat catgatcgat aattacatcg
    11941 cgtacaccgg cagcatgaat atggtcgatc ctcgctactt caaacaagat gcgggcgtag
    12001 ggcaatggat tgatctgatg gcgcgtatgg aaggccctat cgccaccgcg atggggatta
    12061 tttattcctg cgactgggag attgaaaccg gaaaacgtat tctgccgcca ccaccagatg
    12121 tcaatattat gccgtttgaa caggccagcg gtcacaccat tcacacaatt gcttctggcc
    12181 ccggctttcc ggaagatctc attcaccagg cattattgac tgcggcttat tcggcgcgtg
    12241 aatatttgat catgaccacg ccctactttg tgccaagcga tgatttactt catgcgattt
    12301 gcacggcggc gcagcgcggg gtggatgtca gtattatcct tccgcgaaaa aatgactcga
    12361 tgctggtcgg ctgggccagt cgcgcattct ttacggaact gctggctgct ggggttaaaa
    12421 tttatcagtt tgaaggcggg ttactgcata ccaagagcgt gctggtcgat ggcgaactaa
    12481 gtctggttgg cacagttaac cttgatatgc gtagtctgtg gctaaatttc gagattaccc
    12541 tggcaatcga cgataaaggt tttggtgctg acctcgccgc cgttcaggac gattatattt
    12601 cgcgttcacg tctgctcgat gcccgtttat ggctaaaacg tccattatgg caacgtgtcg
    12661 ccgagcgact gttttacttc ttcagtccgt tgctgtaaaa cgtcgccaac agaggttaaa
    12721 caggtagtaa ctatggatat ggatctaaac aatcgcctga ctgaagatga aacgcttgaa
    12781 caggcctacg atatttttct cgaactggct gccgacaatc tcgatccagc tgatgttctg
    12841 ctgttcaatc ttcagtttga agagcgcggc ggcgcggagt tattcgatcc ggcggaagac
    12901 tggcaggaac atgttgattt cgatttgaac ccggactttt ttgccgaagt ggtgattggt
    12961 ctggcggaca gtgaagatgg tgaaatcaac gatgtttttg cccgcattct gttatgccgc
    13021 gaaaaagatc acaaactttg ccatatcatc tggcgggaat aaataatcgc ttttagcgtg
    13081 aaaaatggct gacaactgtc agcccttatt gtttttaaag cggatcgact ttcaggcaag
    13141 aaacggcgtg tctgaaactc ccctccagaa caggacgtgt tttggcgcac tctggaccgg
    13201 caatcgggca acgggtacgg aaaacacaac cggaaggcgg gttgatcggc gacggtaatt
    13261 ccccttccag taactggatg gttttgttct tctccagatc cggatcaggt atggggactg
    13321 ccgacatcaa tgccctggtg taaggatgta gtggattgtg gtagacctca tcataggtcc
    13381 ccagttctac cgcatggccg agatacatca ccaacacacg atcggaaatg tgttttacca
    13441 cggccaggtc atgagcgata aaaattaatg acaatcccat ctcacgttgc aattgctgga
    13501 gcaggttgac cacctgtgcc tgaattgaca cgtccagcgc cgacaccggc tcatcacaga
    13561 taatcagctt cggttcaaga ataagagcac gcgcaatccc gatacgctgg cactgcccac
    13621 cagagaactc atgcggatag cggttaatca ggttaggcaa taacccgact ttcagcatca
    13681 tcgccttcac gcgctcgcga acttcctggc gtgacatttt cggatgataa gtacgcagtg
    13741 gttcagcgat gatctcgccg atggtcatac gcgggtttag cgatgccaac ggatcctgga
    13801 aaatcatctg aatatcactg cgaacggcac gccattcatc gggtttcatg cccagcaact
    13861 ctttacctaa ccaggcaaca tgaccgtcgg tcgccttgac caaaccgatg atggcgcgag
    13921 caaaggtgga cttaccgcat cccgattccc ctaccacacc taatgtttcc ccttcataca
    13981 ggcgaagagt gacaccatcg acggctttga gcgttttcgg cggttgccag aaccactgtt
    14041 tgccatcttt gatttcaaag tgcactttaa gatcggcgat ttcaaggagg acttttcttc
    14101 cttcagttac agcattcata acagttcctc caccggttta aagcaagcac gcagacggcc
    14161 aggcgtaaac tcttccagcg gcggtgcgct actacaaatt tccatcgcat gcggacaacg
    14221 tggctggaac gggcaacctt tcggtaatcg cagcaggttt ggcggattac ccgggatggt
    14281 caacattgtt tcaccttccg catcgagacg cggcaccgcg ttgagcaaac cgatagaata
    14341 aggatgaacg ggttgataaa agacatcgcg cgcgttgcca tattccatcg tgcgcccggc
    14401 gtacattacc agcactttgt cgcagatccc cgccaccacg ccaagatcgt gggtgatcat
    14461 aatgatggcg gtattaaatt cccgcttcag ttcatttaat agcgtcatga tctgcgcctg
    14521 tacggtgacg tccagcgcag ttgttggttc atccgcaatc agcagcttag gtcgacataa
    14581 caaggccatc gcaatcatga ctcgctgacg catgccgcca gaaaattcgt gcgggtacat
    14641 tttcatgcgt ttacgcgctt ccggcatttt taccgcatcg agcatccgca ccgactcttc
    14701 aaacgcctca gctttgctca tgttcttatg cagcatcagc acttccatca actgctcacc
    14761 gacgcgcata tagggattca acgaagtcat tgggtcctga aaaatcattg agatttgttc
    14821 agcgcgcagt ttattgagtt catgctctgg caaattgagg atttcacgcc cattgaaggt
    14881 tgccgatccg ccaatacgtc cgttggcagc caacaggccc atcaacgcaa atgcagtttg
    14941 cgatttaccc gaaccagact cacctacaat acccagcgtt tctccggcac gtagggaaaa
    15001 attcaaatca ttgaccgccg tgacgtcgcc gtccggggta ctaaaggtga cacgcaaatc
    15061 tttcacgttc agcagtgcgt cagcctgttg ttgtgcgagc ggcacagttg cagtttcaat
    15121 tacgctcatg gctgcactcc ttaacgatct ttcgggtcga gggcatcacg caagccatcg
    15181 ccgataaagt tgaaacaaaa cagcgtcacc acgaggaatc ccgctgggaa caacaataac
    15241 catggagaga cttccatcga gttcgcgcca tcactcagca atgcacccca gctgcttaac
    15301 ggctcttgcg tacccaaccc caggaagcta aggaaagatt caaagaggat catgctgggc
    15361 accagaagtg atgcgtagac caccaccaca ccgagtacat tcggcacaat gtggcgaata
    15421 acaatgcccg atgtcgatac accgccaact tgtgccgcct caataaactc tttgcgcttc
    15481 agactcaggg tttgcccacg cacaatacga gccatatcca gccaggaaac catgcctatc
    15541 gccacgaaaa tcagcaggat gttttgaccg aaaaaggtca ccagcaaaat gacgaagaac
    15601 atgaatggga aggagttgag gatttccagc aaacgcatca ttaccgaatc cactttaccg
    15661 cccagataac cggaaagcga accataaagt gtcccgacga ccacagccac cagtgccgca
    15721 gcaacaccga ccatgagtga gatacgcccg ccaatcgcaa cgcgcacaag caggtcgcga
    15781 ccggatgagt cagtaccaaa gtagtgaccg gactccatat ccggggcgct ggacatcatc
    15841 gcccagtcag tatcgtcata ggcaaactgg gaaagcatcg gtgccaggat tacaaataac
    15901 gcgatcagca ccagcactat cagactggca accgccgcac ggttatgcat aaaacgtcga
    15961 cgtgcgtcct gccacaagct gcgcccttcg acctccagct tttcactgaa attttccagc
    16021 gtctcgctgt ttttcttact taacatcatc gcgagctcca gtatcagtaa cggattttcg
    16081 ggtcgataac cgcatatagc acatcgacaa tggcattaaa caaaatggtt aaagcaccaa
    16141 ccaggatggt caggcttaac actaaggaat agtcacggtt caatgcgcca ttaacgaaca
    16201 gttgtccaat ccccggcaaa ccataaatgg tttcgataac catagaaccg gtaataatgc
    16261 cgacaaatgc ggggcccata taagagagca cgggtaacag agcaggtttt aatgcgtgac
    16321 gtaaaatgat ccgccgcata ggtaaccctt tcgcccgggc agtacgaata aaattggagt
    16381 gtaatacttc aatcatagag ccacgggtaa tacgcgcaat actggcgata taagcgagtg
    16441 acaacgccac catcggcaat atcatgaatt taagcgcccc accattccag ccaccgcccg
    16501 gcagccaatg caaaatgatc gcaaatatca tgactaataa tggtgcaacc acaaaactgg
    16561 ggataacaac cccggtcatt gccagcccca tcacggtata gtcccatttg gtgttttgtt
    16621 ttaatgcggc aataacgcca gcactaacac ccagtattac cgcaaggaaa aatgctgcgg
    16681 ctcccagttt ggcagaaacg ggaaaactgg atgcaaccaa gtcattgacc gaataatctt
    16741 tatatttaaa cgatggaccg aaatcaccgt gcgccagttg tttcaggtag ctgaaatact
    16801 gtgtcatgat cggatcatta agatgatatt tcgcttcgat attggccatc acttctggcg
    16861 gtaaagtacg ttcgccggta aaagggcttc ccggcgcgag gcgcatcata aagaacgaaa
    16921 tagtaataag aataaatagc gtcggaatcg cttccagaca gcgacgtaga ataaatttta
    16981 acattgccct accttctggc ctgtgccttc tgtaatgcga taaaaatcag acaccgtgga
    17041 gcaggacact cctgccccac gtattgccat tagtgcttca caatgtacat attccgggta
    17101 taggtattat ccagcggatc tttgccggta tagccaccaa cccacggttt caccagacgc
    17161 gcattcacgt agtaataaac aggaacaatg gccgaatcct tatccagctg ttgttctgct
    17221 ttagtgtaca gagctgtgcg ctgcgcctcg tcagtcactt tcagcgtttc cgccataatg
    17281 ctgtcaaagg ccgggctctt ataatgcgcg gtattcatcg agctgttcga aagcatggtg
    17341 ttcaggaagg aagttggttc gttgtagtca gcacaccagc ctgcacgggc cacatcaaaa
    17401 gtaccctggt gacgggtgtc gaggaacgtt ttccactcct ggttaaccag tttgacgttt
    17461 acaccaatgt ttttcttcca caatgaagag gcagcaatcg ccagcttttt atgcagatcg
    17521 gaggtgttat acaacaggtt gatggtcaac ggtttgtctg cggtataacc cgcttcagcc
    17581 agcagttttt tcgcttcttc gttacgtttt tcctggctcc agccaaacca ttctggctga
    17641 gtcaattttg cgccatcagt atacggtgga gtgtaaccat aggcgggcat gtcgccctgc
    17701 gctttcactt tattaacaat gatatcgcgg tccataccta gtttcagtgc ggtacgcaca
    17761 cgcacatcgt tgaatggcgg tttctggttg ttaatttcgt aatagtaagt gcacaggtat
    17821 ggatcaacgt gaacttcgtc cgggatctct tttttcagct tctggaacaa ttcgatcggc
    17881 atgttgttat acgtcatgtc gatttcacca ctacggtagc ggttgacatc ggtaacttca
    17941 gaagcaatag gcaaataggt tacctggtta ataacggttt tcgcgttgtt ccagtaggtc
    18001 gggctgcgtt caagaacgat tcgttcgttt acgacccaat cttttaaggt ataggcaccg
    18061 ttggtgacga tattaccagg ctgggtccat ttttcgccga atttctcgat agcggctttt
    18121 ggcaccggtg aagttgatgg gtgaacaagt aatttataga agtacggaac gggttcactt
    18181 aaggtgactt ctaatgtgtg atcatcaata gctttcacgc cgagatcggt aatcggtttt
    18241 ttcccttcaa gaatttcatc aataccggcg atatgcccat attgcagata actggcatac
    18301 ggagaagcag tgttcggatc aacagaacgt tgccagctat acacaaagtc ttgtgctgtg
    18361 actggcgtgc catcagacca tttcgcatct ttacgcaaat ggaaggtcca gactttcgcg
    18421 tctttattat cccaggattc agcgacgcca ggtgctggat gaccgtcaag atcgctgacc
    18481 agtaagcctt caaacaggtc tcggctgata ttagactccg gaacaccttc aattttgtgc
    18541 ggatctaatg actgaacttc tgaaccattg ttacgtacca gtgtttgttt ttccgccagt
    18601 gtgacgcctg cgggtacatc agctgccagc gcgacattcc ctgccattag cgcagccaga
    18661 acgccagctg ctactaaact tctcttggtg atgttggtca ttgttttttg gactccctca
    18721 ttataattac tggtattaac cagcatgtgt aatcccggat tgggaccctg cacaggctcg
    18781 gagactttct gctgtcaggt tactttatcg ttacgtatta ctatcaccga ctttatttat
    18841 tctggtgatt cagacgatca ccttatgtcg attcgtactg tgtctcccct gtcgagacac
    18901 attattcttt cgcgacgctc tttaattgtt aattattctc attaccaata aagaatcgtc
    18961 tggcggttgc ccggaaagta ccaaatgcgg ttcttactcg ccaatacatt ttgcaaaatt
    19021 gttaagcaat tctcttttat tgaccgtatc agaatctata gcttgcatcc atgccttaac
    19081 aaatatcttt caattcaatc aaatagagat tggctaagca tgtctatctt ttctgattac
    19141 agttccagta g
//
LOCUS       DAPOAV010000083        18850 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.083, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000083 DAPOAV010000000
VERSION     DAPOAV010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18850
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.083"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(22..228)
                     /locus_tag="RN951_003401"
     CDS             complement(22..228)
                     /locus_tag="RN951_003401"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528353.1"
                     /translation="MPVCPRREKTRAGGAERGRAHAPPLSLRGRSDGGFCFFMPVICL
                     LLMLLFLLLLLLLLLLLFFFFLLL"
     gene            complement(254..819)
                     /locus_tag="RN951_003402"
                     /pseudo
     CDS             complement(254..819)
                     /locus_tag="RN951_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052654.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(867..2228)
                     /locus_tag="RN951_003403"
     CDS             complement(867..2228)
                     /locus_tag="RN951_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3560 domain-containing protein"
                     /protein_id="HDX2528354.1"
                     /translation="MTSAAITMTAPEAASPVQMYRATYSPDDNKLRLYAVSRLDPETY
                     KKVHDAGFRWAPKQALFVAPAWTPGREDVLLSLAGEIEDEDSTLAERQEARAERFTGY
                     SGKRASESAQALDEVERLAAMIPPGQPILVGHHSERRARRDAQRIENGMKRAVMLFER
                     AEYWEERARSALLHAKYKERPDVRWRRIKKIEADLRKAEKTIAQSQKYLTMWRAESLD
                     LNMAKLISSHDHISACFPLDTYPRPAEKSQYEGSRSLWSALDDDIITTEQAREIAIRC
                     HERQIQHQQRWVNHYQNRLIYERAMLDESGGVVTRTQDFEPGGQVFSRGEWLTIIRVN
                     KSNGAVSSVTTPNYSFLGYSGTMKVTPDRITDYKAPSAEEAAVASQAAKRPPVVNYPG
                     EGFREMTKAQWAALPRDCKAVRSVAEAEDHGAYRYRRTMDNNFRLVNVYITDMKITEI
                     PQK"
     gene            complement(2280..2510)
                     /locus_tag="RN951_003404"
     CDS             complement(2280..2510)
                     /locus_tag="RN951_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528355.1"
                     /translation="MTVSIVSPSAAAVKPRRHPRFRREDIPAPEIDPVLKAFGRHIAR
                     SFHRGRGVHIPAMKNTAFGQVLRTLELKRAFN"
     gene            3022..3270
                     /locus_tag="RN951_003405"
     CDS             3022..3270
                     /locus_tag="RN951_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001403191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528356.1"
                     /translation="MSRDPPQRRRARARNGVAPYIPAAFCRDAGSAGHGATEAARPER
                     SLQACGFHASDRSDSPKPRQRVRRRLAGAPAAACRSRA"
     gene            complement(3542..3733)
                     /locus_tag="RN951_003406"
     CDS             complement(3542..3733)
                     /locus_tag="RN951_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528357.1"
                     /translation="MNISTETREILRNYKAVINARRREMGQKPLTTAQIVDEICDFVA
                     NQQAVFLGGHYILQGSRNR"
     gene            complement(3730..4152)
                     /locus_tag="RN951_003407"
     CDS             complement(3730..4152)
                     /locus_tag="RN951_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 family protein"
                     /protein_id="HDX2528358.1"
                     /translation="MYCTVKEIIRDVLDTDVPDSECVFAVVLTRGDVRHIAQDWNLSD
                     DELETVMQRLDDAFEYGADVSIVHDVVRELMEEKRASRQVTVPAVMLEKVMALAGSEM
                     KRLYAVGSENGGDGDAFVREEREAMDVVLQALDGEHMS"
     gene            complement(4199..4501)
                     /locus_tag="RN951_003408"
     CDS             complement(4199..4501)
                     /locus_tag="RN951_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HDX2528359.1"
                     /translation="MMPEYEGGFWHFIRLPDGGGYMMPDGDRFHLVNGENWFDRTVSA
                     DAAGIILTSLVINRQLWLYHDSGDAGLTHLYRMRDAQLWSHIEFHPECNAIYAALD"
     gene            complement(5038..5808)
                     /locus_tag="RN951_003409"
     CDS             complement(5038..5808)
                     /locus_tag="RN951_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528360.1"
                     /translation="MNETLNALIYRHASNLLLAQGWPEETDVDQRNPKYPGWISIYVR
                     LDVPRLATLLINRHGGVLPPLLASAIQKLTGTGAELVLSGSQWQSLPVLPADGTQVFF
                     PYAGEWLTEDEIRAVLDAVRNAVRSICYQVAEDARRIRAALTTTGQTLLTRQTRRFRL
                     VVKESDYPCWLDEDDENLPVVLDAILNRGARFSSVEMYLVSECVEHILSSGLACDVLR
                     IPDEPSRRWFDRDILREMVLEARTEIRSMADALAKIRK"
     gene            complement(5853..6287)
                     /locus_tag="RN951_003410"
     CDS             complement(5853..6287)
                     /locus_tag="RN951_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001562898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 domain-containing protein"
                     /protein_id="HDX2528361.1"
                     /translation="MYGTCETLCRELAAKYPGNTPLMLLIWSPEEIQALADGMDISLS
                     DHEIRTVLARLEDIPEDQRTESGISSGAAMEIINNVRENRQVTVPAELLASLIQTAEQ
                     ALWKREWAARDNGLAVPECVTRRQAVVNQARALLKNNTREND"
     gene            complement(6301..6522)
                     /locus_tag="RN951_003411"
     CDS             complement(6301..6522)
                     /locus_tag="RN951_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528362.1"
                     /translation="MNYAGHEKLRADVAEVANTMCDLRARLNDMEHRCRFDSDVLVER
                     LTRQTLYRANRLFMEAYTEILELDSCFKD"
     gene            complement(6523..7206)
                     /locus_tag="RN951_003412"
     CDS             complement(6523..7206)
                     /locus_tag="RN951_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858331.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methylase"
                     /protein_id="HDX2528363.1"
                     /translation="MSRFVLGNCIDVMARIPDNAIDFILTDPPYLVGFRDRFGRTIAG
                     DKTDEWLQPACNEMYRVLKKDALMVSFYGWNRVDRFMAAWKNAGFSVVGHLVFTKNYT
                     SKAAYVGYRHECAYILAKGRPRLPQNPLPDVLGWKYSGNRHHPTEKPVTSLQPLIESF
                     THPNAIVLDPFAGSGSTCVVALQSGRRYIGIELLEQYHRAGQQRLAAVQRAMQQGAAN
                     DNWFEPEAA"
     gene            complement(7283..7587)
                     /locus_tag="RN951_003413"
                     /pseudo
     CDS             complement(7283..7587)
                     /locus_tag="RN951_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052644.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7591..8493)
                     /locus_tag="RN951_003414"
     CDS             complement(7591..8493)
                     /locus_tag="RN951_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1281 domain-containing protein"
                     /protein_id="HDX2528364.1"
                     /translation="MYFSGEPAQIAEIKRLASGAVTPLYRRATNEGIQLFLAGSAGLL
                     QTTEDVRFEPCPGLTAAGRGVVSPENIAFTRWLTHLQDGVLLDEQNCLMLHELWLQSG
                     TGQRRWEGLPDDVRDTITALFTAKRGDWCGFWSNEAVSVWWNRLCDNVLPEKTMPFDL
                     LTVLPTRLDVEVNGFNGGVLNGVLSAYHWYTEQYGVKWPVGYEVNISSQGDNFIQVDF
                     DTPWCQPESDVIAELSRRFSCTMEHWYAEQGCNFCGWQRYERGELVDVLWGELEWSSP
                     TDDDELPEVTGPAWIVDNVAHYGG"
     gene            complement(9231..10202)
                     /locus_tag="RN951_003415"
     CDS             complement(9231..10202)
                     /locus_tag="RN951_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family plasmid partition
                     protein"
                     /protein_id="HDX2528365.1"
                     /translation="MKRAPVIPKHTLNTQPVEDTSLSTPAAPMVDSLIARVGVMARGN
                     AITLPVCGRDVKFTLEVLRGDSVEKTSRVWSGNERDQELLTEDALDDLIPSFLLTGQQ
                     TPAFGRRVSGVIEIADGSRRRKAAALTESDYRVLVGELDDEQMAALSRLGNDYRPTSA
                     YERGQRYASRLQNEFAGNISALADAENISRKIITRCINTAKLPKSVVALFSHPGELSA
                     RSGDALQKAFTDKEELLKQQASNLHEQKKAGVIFEAEEVITLLTSVLKTSSASRTSLS
                     SRHQFAPGATVLYKGDKMVLNLDRSRVPTECIEKIEAILKELEKPAP"
     gene            complement(10202..11368)
                     /gene="sopA"
                     /locus_tag="RN951_003416"
     CDS             complement(10202..11368)
                     /gene="sopA"
                     /locus_tag="RN951_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid-partitioning protein SopA"
                     /protein_id="HDX2528366.1"
                     /translation="MKLMETLNQCINAGHEMTKAIAIAQFNDDSPEARKITRRWRIGE
                     AADLVGVSSQAIRDAEKAGRLPHPDMEIRGRVEQRVGYTIEQINHMRDVFGTRLRRAE
                     DVFPPVIGVAAHKGGVYKTSVSVHLAQDLALKGLRVLLVEGNDPQGTASMYHGWVPDL
                     HIHAEDTLLPFYLGEKDDVTYAIKPTCWPGLDIIPSCLALHRIETELMGKFDEGKLPT
                     DPHLMLRLAIETVAHDYDVIVIDSAPNLGIGTINVVCAADVLIVPTPAELFDYTSALQ
                     FFDMLRDLLKNVDLKGFEPDVRILLTKYSNSNGSQSPWMEEQIRDAWGSMVLKNVVRE
                     TDEVGKGQIRMRTVFEQAIDQRSSTGAWRNALSIWEPVCNEIFDRLIKPRWEIR"
     gene            complement(11956..12711)
                     /gene="repE"
                     /locus_tag="RN951_003417"
     CDS             complement(11956..12711)
                     /gene="repE"
                     /locus_tag="RN951_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepE"
                     /protein_id="HDX2528367.1"
                     /translation="MAETAVINHKKRKNSPRIVQSNDLTEAAYSLSRDQKRMLYLFVD
                     QIRKSDGTLQEHDGICEIHVAKYAEIFGLTSAEASKDIRQALKSFAGKEVVFYRPEED
                     AGDEKGYESFPWFIKRAHSPSRGLYSVHINPYLIPFFIGLQNRFTQFRLSETKEITNP
                     YAMRLYESLCQYRKPDGSGIVSLKIDWIIERYQLPQSYQRMPDFRRRFLQVCVNEINS
                     RTPMRLSYIEKKKGRQTTHIVFSFRDITSMTTG"
     gene            complement(13433..14239)
                     /locus_tag="RN951_003418"
     CDS             complement(13433..14239)
                     /locus_tag="RN951_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HDX2528368.1"
                     /translation="MSGSVIHSQSAAMVPAVYSAGQSAQLPVAIDYPAALALRQMSMV
                     HDELPKYLLAPEVSALLHYVPDLRRKMLLATLWNTGARINEALALTRGDFSLTPPYPF
                     VQLATLKQRTEKAARTAGRMPAGQQTHRLVPLSDSWYVSQLQTMVATLKIPMERRNRR
                     TGRTEKARIWEVTDRTVRTWIGEAVAAAAADGVTFSVPVTPHTFRHSYAMHMLYAGIP
                     LKVLQSLMGHKSISSTEVYTKVFALDVAARHRVQFAMPESDAVAMLKQLS"
     gene            complement(14240..14545)
                     /gene="ccdB"
                     /locus_tag="RN951_003419"
     CDS             complement(14240..14545)
                     /gene="ccdB"
                     /locus_tag="RN951_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin CcdB"
                     /protein_id="HDX2528369.1"
                     /translation="MQFKVYTYKRESRYRLFVDVQSDIIDTPGRRMVIPLASARLLSD
                     KVSRELYPVVHVGDESWRMMTTDMASVPVSVIGEEVADLSHRENDIKNAINLMFWGI"
     gene            complement(14547..14765)
                     /gene="ccdA"
                     /locus_tag="RN951_003420"
     CDS             complement(14547..14765)
                     /gene="ccdA"
                     /locus_tag="RN951_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin CcdA"
                     /protein_id="HDX2528370.1"
                     /translation="MKQRITVTVDSDSYQLLKAYDVNISGLVSTTLQNEARRLRAERW
                     QAENQEGMAEVARFIEMNGSFADENRDW"
     gene            15325..15555
                     /locus_tag="RN951_003421"
     CDS             15325..15555
                     /locus_tag="RN951_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HDX2528371.1"
                     /translation="MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIVREGDSIILRPVR
                     PTWGSFLELEKADPDFMTEREDVVSDEGRVNL"
     gene            15552..15968
                     /locus_tag="RN951_003422"
     CDS             15552..15968
                     /locus_tag="RN951_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HDX2528372.1"
                     /translation="MNKIYMLDTNICSFIMREQPEALLKHLEQSVLRGHRIVVSAITY
                     SEMRFGATGPKASPRHVQLVDAFCERLDAVLPWDRAAVDATTEIKVALRLAGTPIGPN
                     DTAIAGHAIAACAILVTNNVREFERVPGLVLEDWVR"
     gene            16043..17608
                     /locus_tag="RN951_003423"
     CDS             16043..17608
                     /locus_tag="RN951_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDX2528373.1"
                     /translation="MPLITRLMLQNFKKFPELDLRFSNDRNILVGDNESGKSTILLAL
                     DLVLSDSRHRVEALGVESLLSQSAVRHFQEGERRADQLPVLTADVFLSNGGEPDLNGR
                     QNLAGIDADGLRMRIAPMMEEYGQDIHHVLQQDPDNFPYEYYSVQFSTFSGGHFAGFR
                     RYLRHLFLDSARIDNEHAAQEYTRTVYSVNVPVADRYRLENSYRQQKMHFCARHLSAI
                     NDTLKTYQFGVRSGAKSGLEANLDITEDGISIRHRGKGRQCFIKTEFALQRHQQQGGE
                     IHALLLEEPENHLSHVSMKRLVNQLATERQTQVFIATHSSHISSRLDLRKAILLGATR
                     PVLMNELSAETAAFFMKAPDNNVLEFALARRVLLVEGDAEFILIEAFYHRLYGRAPED
                     DGVHIIAIGGTSFRRYLELARLLENRVAALRDNDGNYQQNCDERYADVLCSRSRVFAD
                     HDNSRSTFEICLYQDNADLCDALFRGTRRTLTVQDYMLANKAEAAFQLLQLHAEKLTV
                     PDYIQEALAWIRE"
     gene            17593..18615
                     /locus_tag="RN951_003424"
     CDS             17593..18615
                     /locus_tag="RN951_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrD"
                     /protein_id="HDX2528374.1"
                     /translation="MDKRVIFAVAGSGKTTLLIRRLREDRRTLILTFTVNNEAHLRAQ
                     IIRRFGYIPYGIRVMTWFEFLHGFCFRPFLQEQLSSRGLSFNQPPSRIPRTNIRHYQD
                     PAGRLYHRRLAHLLTARGLLPDIRTRLARYYDELFVDEVQDFAGHDFNFLLELCRAEI
                     SVLCCGDFYQHTFDTSRDGNVNATLHEDITRYEARFRAAGIMVDCETLSRTWRCSATV
                     CEFITGQLNIRISAHGTHTTQIEIVTDEARSAALHADNTMIKLFYREHHRYGCHSMNW
                     GGSKGLDHFQDVCIVMGANHWMRLIQQKLAALPPSSRNRLYVACSRARGNIYFIPESH
                     LRRFRN"
BASE COUNT         4514 a         5229 c         4850 g         4257 t
ORIGIN      
        1 acaacactgc agtagtcaga atcagagcag caggaaaaag aagaacagta gcagtagcag
       61 tagcagtagc agtagcagga acaacaacat cagtaacaga caaatgacag gcatgaagaa
      121 acagaagccc ccatcagaac gtccgcgtaa tgaaaggggc ggcgcgtgag cgcggcccct
      181 ttcagcgcca ccggcgcgcg ttttttcccg gcgcgggcag acaggcattt atcctcccgc
      241 cggccctgtg tcatcaggca cgcagacgaa taatcatcgt cgggacatcg gtataagcaa
      301 acgtgccgcg cggcagctcc tcgcggacgt cagaaaacgg taacagcttc tcctgctggc
      361 gtggtccgtt gagacagacg gcgaccagca cgccacccgg acgcaacagg gaaaaggccc
      421 gcaggatatg ccggatatcc tgcccgtggc tgaacggcgg attcatgata acccggctgt
      481 aatactgcac cggctgccat tccatgaagt cgccacactg aaccccctga caccgttaaa
      541 attttcccgc agataccgaa ccagcccgct gttgatttcc accgcatcac acatggcccc
      601 cggcgcggta tcccgaatcg cccgcagtat ggccccggtg ccggcagagg gttccagaat
      661 gtaatcacgg ttgctgatct ccgccagcat caccaggcga tcacagaccg gggcaggagt
      721 cacaaaaagc tgagattcag cccggatttc agcaaccggc gcggcgttat ccagccttgc
      781 gcgcatcagc cggatacgtt ctcttaactg actgtgcata tcattatctc cgtcatcccc
      841 cggggatttt cccgggggga tataccttat ttctgtggga tttccgtgat tttcatgtcg
      901 gtgatataca cattcaccag gcggaaatta ttgtccattg tgcggcggta ccggtatgcc
      961 ccgtggtctt ctgcttctgc cacactacgc acggccttac agtcccgggg cagggcggcc
     1021 cactgtgcct ttgtcatttc ccggaaacct tcccccggat agttgactac cggcggacgc
     1081 ttcgcggcct gactggcgac ggcagcctct tctgccgatg gtgctttgta gtccgtgatg
     1141 cgatcgggcg tcactttcat cgtgccgctg tacccaagaa aactgtaatt tggcgttgtg
     1201 actgaactca ccgccccgtt gcttttgttc acacggatga tggtcagcca ctcgccccgg
     1261 ctgaaaacct gtccgcccgg ctcaaaatcc tgtgtccggg taaccacgcc gccgctttcg
     1321 tccagcatgg cacgctcata gatcaggcgg ttctgatagt ggttaaccca gcgttgttga
     1381 tgctgaatct gccgctcatg acagcggatc gcaatttcgc gggcctgctc cgtggtgatg
     1441 atgtcatcat ccagggccga ccataacgat cgacttcctt catactggct tttttctgcc
     1501 gggcgcggat acgtatccag cgggaaacag gcgctgatat ggtcatgact gctgatgagt
     1561 tttgccatat tcagatccag cgattcagcc cgccacatcg tcagatattt ctgcgactgc
     1621 gcgatggtct tttcagcctt gcgcaaatca gcttcgattt ttttgatacg acgccagcga
     1681 acgtccggac gttctttata cttcgcgtga agcagtgccg accgcgcccg ctcttcccag
     1741 tattccgcac gttcaaagag catcacggct cgtttcatgc cgttttcaat acgctgcgca
     1801 tcacgacggg cgcggcgttc gctgtgatgc cccacaagaa tgggctgacc gggcgggatc
     1861 atcgcggcca gtctttccac ttcatcaagt gcctgtgcgg attcactggc ccgctttccg
     1921 ctgtatccgg taaaccgctc cgcccgtgct tcctgacgtt cagcgagcgt gctgtcttca
     1981 tcctcaatct ctccggcaag tgagaggagc acgtcttccc ggcccggtgt ccaggctggc
     2041 gcgacaaaca gcgcctgttt tggtgcccag cggaaaccgg catcatgcac ttttttatac
     2101 gtctccgggt caagacgtga cacggcatac aggcgcagtt tgttgtcatc cggtgagtag
     2161 gtcgcgcggt acatctgcac agggctggcg gcttccgggg cggtcatggt gattgctgct
     2221 gatgtcataa aatgttctcc ttccgtctgt tgccgcccct cacggggcgg ctcacctcat
     2281 cagttaaaag cgcgtttcag ttcgagtgtg cggagcacct gcccgaaggc cgtgtttttc
     2341 atggcgggga tgtgtacacc acgcccccgg tgaaaactcc gggcaatgtg tcgcccgaag
     2401 gctttcagca cggggtcaat ttccggcgcg gggatgtctt cgcgtctgaa acggggatga
     2461 cggcggggct ttacagccgc tgcggaaggt gaaacaatac ttactgtcat aaatgcatcc
     2521 ttatgactgt tgaatggaac cgcagaaact gcgcgaacag tttttgcggt gtggattaag
     2581 caggtccctg acctgctttt ttcatatctg cgtctgacgt tctccggtgt tttcctcctt
     2641 ctgttcctgc gttctcatta cctgccagcc ggatgactga cagaacaaat aaatgcatat
     2701 tgccggagcc tgaaataaat cctgattttt aaagaacatc acccgttgag tttcgggagc
     2761 cgcggttttg acgtttcgcg ggaacctgct gctgtattcc ctgtggtatg aacttcaccc
     2821 gtttgagaac cttcgccgca aggggcatca ctgccacggc ctgacgcacc tgtcctgggc
     2881 agaacgcaaa attttttacc gggttttggg taaaaaattt tgtgggctgt tcatttaccc
     2941 tagacagtca gtgcggcagg ttgtggctgt atcagccccc ggcgacaggg actcatacgg
     3001 gtgtgtggca cccggcaggc aatgagcagg gacccgccgc aacgacggag agcgcgtgcg
     3061 cgaaacggcg ttgcgcctta catcccggcg gccttttgcc gggatgccgg gagcgcaggc
     3121 cacggcgcga cagaggcggc gcgaccggaa cggtcgctgc aagcctgtgg ttttcacgca
     3181 tcggaccgta gcgacagccc gaaaccgcgc cagcgggttc ggcggagact ggcaggtgcg
     3241 ccagcagctg cctgtcggag tcgggcctga cgaccggatg ccgccaggca gccgggagcc
     3301 gaaggtgcgc ccggcagaca gaacaacact gcagtagtca gaatcagagc agcagataaa
     3361 ggaacaacaa catcaggaac agttccataa cataagaaag aaacactcct gagtcagaca
     3421 catcacagac gggaagggta acgggcgacg cgccagcgtg gcccgcttcc cttccggcag
     3481 gcgtcagcct gccaggggtt ttcgcgcggg ctgacaggcg gccttcaccg cctgccctgt
     3541 atcacctgtt tctgctgccc tgtaagatgt agtgaccgcc caggaaaaca gcctgctgat
     3601 tcgccacaaa atcgcagatt tcatcaacaa tctgcgcggt ggtgagcggt ttctgcccca
     3661 tttcacgacg tcgcgcatta atcacggctt tgtaattgcg cagaatttcg cgggtttctg
     3721 tgctgatatt catgacatgt gctccccgtc cagcgcctgt aacacaacgt ccattgcttc
     3781 gcgttcctcc ctgacgaacg catcaccgtc gcccccgttc tcactcccga cggcatacag
     3841 gcgcttcatt tcactgcctg ccagcgccat cactttttcc agcatcaccg ccggaactgt
     3901 cacctgacgg ctggcacgct tttcttccat cagctcacga acaacgtcgt gaacaatgct
     3961 gacatccgca ccatattcaa aggcatcgtc cagccgctgc atgacggttt ccagctcatc
     4021 gtctgacagg ttccagtcct gggctatgtg gcgcacatcc ccacgggtca gcaccacggc
     4081 aaaaacgcat tcactgtccg gcacgtctgt atccagtaca tcgcggatga tttctttaac
     4141 agtacagtac atgttctcgt ctcctttaca ggggcggcat tgccgccccg tccgttaatc
     4201 agtccagtgc cgcgtaaatc gcgttgcatt cggggtgaaa ttcgatgtgg ctccacaact
     4261 gcgcatcgcg catcctgtac aggtgtgtca accctgcatc cccgctgtcg tggtacagcc
     4321 acaactggcg gttaatcaca agggaagtca gaatgatgcc tgcggcatca gcactcacgg
     4381 tacggtcaaa ccagttttca ccgttgacca gatgaaaacg gtcgccatcc ggcatcatgt
     4441 aaccgccacc gtccggcagg cggatgaagt gccagaatcc gccttcatat tccggcatca
     4501 tttttttcgc cagcgcgtat acagacgctt cggcatacag aaaatccagg ccaaacaggt
     4561 aaggcagaaa agacagacgg tcgcactctt caacgttcag agtgacaggt ttcgcatact
     4621 gcatgggatt tcctccgttg ttcacatatt ccgcgacacc gggcggtgcc gtgcctccat
     4681 ctttgccggg cctgcagggt tgcaagggcg caagggaagc cgcagcctga cgcgcacggc
     4741 tgacgggagt tggagggtga gaccgcgaaa tctgagcggg tgaacgaccg gaaaatcacg
     4801 gcagacggga aggagggacc gggtgaccgc agcggttcac cttaccttgc aacccgcccg
     4861 cagaagcccg gctacgatgg aggcacggca cagcccgcac acgacgctga ggccacataa
     4921 ctgaaaaccc acaaggccat gccccgcatg gccgggtaaa gcggagcctg cggcgacatc
     4981 cttttgctct ttccggggac cggctggaaa aggcggagat tttccccgcc agcgtcatca
     5041 tttccggatt ttcgccagtg catccgccat gctgcggatt tcagtccggg cttccaggac
     5101 catctcccgc agaatatccc ggtcaaacca gcgacgggac ggttcatcag gtatacgcag
     5161 cacatcgcag gccagcccac tggacaggat atgctccaca cactcactga ccagatacat
     5221 ttccaccgac gaaaaacgag cgccacggtt cagaatggca tcgagcacca cgggcagatt
     5281 ttcgtcatct tcatcaagcc agcaggggta atcgctttcc ttcacaacca gacgaaagcg
     5341 gcgcgtctgg cgggtcagca acgtctgacc ggtggtggtc agcgccgccc ggatacgccg
     5401 ggcatcttct gccacttggt aacagatgct tcgtactgca ttgcgcactg catcaagaac
     5461 tgccctgatt tcgtcttcgg tcagccattc tccggcatac gggaaaaaca cctgtgttcc
     5521 gtctgccgga agtaccggca gcgactgcca ctgactgccg gacagtacca gttccgcccc
     5581 ggttccggtc agtttctgaa tggcggaggc caggagcggc ggcagtacgc cgccgtgacg
     5641 gttgataagt aacgtcgcca gccggggcac atccagccgc acgtaaatgc tgatccagcc
     5701 cggatacttc ggattacgct ggtcaacatc cgtctcttcc ggccagccct gcgccagcag
     5761 caggttgctg gcgtggcgat aaatcagtgc attcagcgtt tcgttcatga ttcatggtct
     5821 ccctgaatcg ccgcccgcag gcggcgataa catcagtcgt tttcgcgtgt gttgtttttc
     5881 agcagggcgc gggcctgatt aaccaccgcc tgtcggcggg tgacgcattc cgggacggcg
     5941 aggccgttat cacgggcggc ccactcacgt ttccacagtg cctgttcggc ggtctgaatc
     6001 agggacgcca gcagttcagc agggacggtc acctggcggt tttctctcac gttattgata
     6061 atctccatcg ccgcaccgga agaaataccg gattcagtcc gctggtcttc cgggatgtcc
     6121 tccaggcgcg ccaggacggt tctgatttca tgatcggaca gagaaatatc cattccgtca
     6181 gcgagggcct gaatctcttc cggggaccag ataagcagca tcagcggcgt gtttcccgga
     6241 tactttgctg ccagctcccg gcatagcgtt tcgcatgttc cgtacattct cgtctccttc
     6301 tcaatctttg aagcaggaat ccagttccag aatttcggta tacgcctcca tgaacaggcg
     6361 attggcgcga tacagcgtct ggcgtgtcag gcgttcaaca agcacatcgg aatcaaagcg
     6421 acagcgatgc tccatatcgt tcagcctggc ccgaaggtca cacatggtgt tggccacctc
     6481 cgccacgtcg gcgcgaagtt tttcgtgtcc ggcatagttc atttacgcag cctccggttc
     6541 aaaccagtta tcattcgcgg ccccctgctg catggcccgt tgcacggcgg ccagtcgttg
     6601 ctgtccggca cggtgatact gttcaagcag ctcgataccg atataccggc gtccggactg
     6661 gagggcaacg acgcaggttg agccgctgcc tgcaaacggg tccagcacaa ttgcgttcgg
     6721 gtgtgtgaag ctctcaatca gcggttgcag gctggtaacg ggcttttccg tcgggtgatg
     6781 acgattgccc gaatatttcc agcccagcac gtccggcagc gggttttgtg gcagacgtgg
     6841 acggcctttt gccaggatgt aggcgcattc gtggcgatag cccacatatg cggccttcga
     6901 tgtgtagttt ttggtgaaga ccaggtgacc aacaacgctg aatcccgcat ttttccaggc
     6961 ggccataaag cgatcgacgc ggttccagcc gtagaagctc accatcagcg cgtctttttt
     7021 gagtacgcgg tacatttcat tacaggccgg ttgcagccat tcatcggttt tatcgccggc
     7081 gatggtgcgc ccgaaacggt cacgaaaacc gacgaggtac ggcgggtcag tcagtatgaa
     7141 atcaatggcg ttatcaggaa tacgggccat aacatcgatg cagttaccga ggacaaaacg
     7201 ggacataaca acgctccttc tcttacagag gacaccggga gggcacccct gtggtgcccg
     7261 ttccccgctg cctgtgggct gttcaccgcg tccggtaacg ggtcaggccg accgtggaat
     7321 accgcagccg tcgtctttct gacggcaagg ctatgccgcg aaagcggctt gaagggcgtt
     7381 catcagaaaa gggcgacggg ctggcgtaca ctgtcaccgg tgccagccgg gagcggtaaa
     7441 agcgcccgtc ccgtgcccac cggacgcggg acactgacca caggcagcgt tcctgccgcg
     7501 ccgcgtcagc cggcgcagta aaaagaggag cccggcgaca tcctttaccg gaaaagaaac
     7561 gggcggttgc ccgcccgtct ccgtcatact tcatccgcca taatgcgcca cattgtcgac
     7621 tatccacgca ggtccggtga cttccggcag ctcatcgtca tctgtcgggg aagaccattc
     7681 cagctccccc cacagcacat caacaagctc gccacgctca tatcgctgcc agccacagaa
     7741 attgcagccc tgttcggcat accagtgctc cattgtgcag ctgaaacggc ggcttaattc
     7801 tgcaataacg tcgctttccg gctgacacca cggcgtgtcg aaatccacct gaatgaagtt
     7861 gtctccctga ctgctgatat tcacctcata ccccacaggc cacttcacgc catactgttc
     7921 cgtataccag tgatatgcag aaagaacacc gttcagaaca ccaccgttaa agccattcac
     7981 ttcaacatcc aggcgggtgg gcagaaccgt cagcaggtca aacggcatgg ttttttccgg
     8041 cagtacgttg tcacacagac ggttccacca caccgataca gcctcgttac tccagaagcc
     8101 acaccagtca cctctttttg cggtgaaaag tgcggtgatg gtatccctga catcgtccgg
     8161 taatccttcc cagcgacgct gtccagtacc gctctgcagc cagagttcat gcagcatcag
     8221 gcagttttgc tcatccagca gtacaccgtc ctgcaggtgt gtcagccagc gggtgaacgc
     8281 gatattctcc ggcgatacaa cgccacgccc ggcagccgtc agtccggggc atggttcaaa
     8341 ccgcacatct tcagtggtct gcagaagtcc ggcacttccg gccagaaaca gctgaatacc
     8401 ttcatttgtg gcgcggcgat aaagtggtgt gactgcaccg ctggccagtc gtttaatctc
     8461 agcgatctgt gccggttcac cagaaaaata catacgattc gagcaccagt ttggcatggg
     8521 aattctcctc tcacatgcgg cctccatcag gccgtgccgc acctgtaacc gggcgaccgc
     8581 atacgaatgc aggtgcggcc ccgaagccgc agcgcgtgga ggaggaacga cgaaacgtga
     8641 ccgggtgagg aggccggcga cagcgacaca cttgcatcgg atgcagcccg gttaacgtgc
     8701 cggcacggcc tgggtaacca ggtattttgt ccacataacc gtgcgcaaaa tgttgtggat
     8761 aagcaggaca cagcagcaat ccacagcagg catacaaccg cacaccgagg ttactccgtt
     8821 ctacaggtta cgacgacatg tcaatacttg cccttgacag gcattgatgg aatcgtagtc
     8881 tcacgctgat agtctgatcg acaatacaag tgggaccgtg atcccagacc gataatcaga
     8941 ccgacaacac gagtgggatc gtggtcccag actaataatc agaccgacga tacgagtggg
     9001 accgtggtcc cagactaata atcagaccga cgatacgagt gggaccatgg tcccagacta
     9061 ataatcagac cgacgatacg agtgggaccg tggtcccaga ctaataatca gaccgacgat
     9121 acaagtggaa cagtgggccc agagagaata ttcaggccag ttatgctttc tggcctgtaa
     9181 caaaggacat taagtaaaga cagataaacg tagactaaaa cgtggtcgca tcagggtgct
     9241 ggcttttcaa gttccttaag aatggcctca attttctcta tacactcagt tggaacacga
     9301 gacctgtcca ggttaagcac cattttatcg cccttataca atactgtcgc tccaggagca
     9361 aactgatgtc gtgagcttaa actagttctt gatgcagatg acgttttaag cacagaagtt
     9421 aaaagagtga taacttcttc agcttcaaat atcaccccag cttttttctg ctcatgaagg
     9481 ttagatgcct gctgcttaag taattcctct ttatctgtaa aggctttttg aagtgcatca
     9541 cctgaccggg cagatagttc accggggtga gaaaaaagag caacaactga tttaggcaat
     9601 ttggctgtgt tgatacagcg ggtaataatc ttacgtgaaa tattttccgc atcagccagc
     9661 gcagaaatat ttccagcaaa ttcattctgc aatcggcttg cataacgctg accacgttca
     9721 taagcacttg ttgggcgata atcgttaccc aatctggata atgcagccat ctgctcatca
     9781 tccagctcgc caaccagaac acgataatca ctttcggtaa gtgcagcagc tttacgacgg
     9841 cgactcccat cggcaatttc tatgacacca gatactcttc gaccgaacgc cggtgtctgt
     9901 tgaccagtca gtagaaaaga agggatgaga tcatccagtg cgtcctcagt aagcagctcc
     9961 tggtcacgtt cattacctga ccatacccga gaggtcttct caacactatc accccggagc
    10021 acttcaagag taaacttcac atcccgacca catacaggca aagtaatggc attaccgcga
    10081 gccattactc ctacgcgcgc aattaacgaa tccaccatcg gggcagctgg tgtcgataac
    10141 gaagtatctt caaccggttg agtattgagc gtatgttttg gaataacagg cgcacgcttc
    10201 attatctaat ctcccagcgt ggtttaatca gacgatcgaa aatttcattg cagacaggtt
    10261 cccaaataga aagagcattt ctccaggcac cagttgaaga gcgttgatca atggcctgtt
    10321 caaaaacagt tctcatccgg atctgacctt taccaacttc atccgtttca cgtacaacat
    10381 tttttagaac catgcttccc caggcatccc gaatttgctc ctccatccac ggggactgag
    10441 agccattact attgctgtat ttggtaagca aaatacgtac atcaggctcg aaccctttaa
    10501 gatcaacgtt cttgagcaga tcacgaagca tatcgaaaaa ctgcagtgcg gaggtgtagt
    10561 caaacaactc agcaggcgtg ggaacaatca gcacatcagc agcacatacg acattaatcg
    10621 tgccgatacc caggttaggc gcgctgtcaa taactatgac atcatagtca tgagcaacag
    10681 tttcaatggc cagtcggagc atcaggtgtg gatcggtggg cagtttacct tcatcaaatt
    10741 tgcccattaa ctcagtttca atacggtgca gagccagaca ggaaggaata atgtcaagcc
    10801 ccggccagca agtgggcttt attgcataag tgacatcgtc cttttcccca agatagaaag
    10861 gcaggagagt gtcttctgca tgaatatgaa gatctggtac ccatccgtga tacattgagg
    10921 ctgttccctg ggggtcgtta ccttccacga gcaaaacacg tagccccttc agagccagat
    10981 cctgagcaag atgaacagaa actgaggttt tgtaaacgcc acctttatgg gcagcaaccc
    11041 cgatcaccgg tggaaatacg tcttcagcac gtcgcaatcg cgtaccaaac acatcacgca
    11101 tatgattaat ttgttcaatt gtataaccaa cacgttgctc aacccgtcct cgaatttcca
    11161 tatccgggtg cggtagtcgc cctgctttct cggcatctct gatagcctga gaagaaaccc
    11221 caactaaatc cgctgcttca cctattctcc agcgccgggt tattttcctc gcttccgggc
    11281 tgtcatcatt aaactgtgca atggcgatag ccttcgtcat ttcatgacca gcgtttatgc
    11341 actggttaag tgtttccatg agtttcattc tgaacatcct ttaatcattg ctttgcgttt
    11401 ttttattaaa tcttgcaatt tactgcaaag caacaacaaa atcgcaaagt catcaaaaaa
    11461 ccgcaaagtt gtttaaaata agagcaacac tacaaaagga gataagaaga gcacatacct
    11521 cagtcactta ttatcactag cgctcgccgc agccgtgtaa ccgagcatag cgagcgaact
    11581 ggcgaggaag caaagaagaa ctgttctgtc agatagctct tacgctcagc gcaagaagaa
    11641 atatccaccg tgggaaaaac tccaggtaga ggtacacacg cggatagcca attcagagta
    11701 ataaactgtg ataatcaacc ctcatcaatg atgacgaact aacccccgat atcaggtcac
    11761 atgacgaagg gaaagagaag gaaatcaact gtgacaaact gccctcaaat ttggcttcct
    11821 taaaaattac agttcaaaaa gtatgagaaa atccatgcag gctgaaggaa acagcaaaac
    11881 tgtgacaaat taccctcagt aggtcagaat aaatgtgacg aaccaccctc aaatctgtga
    11941 cagataaccc tcagactatc ctgtcgtcat ggaagtgata tcgcggaagg aaaatacgat
    12001 atgagtcgtc tggcggcctt tctttttctc aatgtatgag aggcgcattg gagttctgct
    12061 gttgatctca ttaacacaga cctgcaggaa gcggcggcgg aagtcaggca tacgctggta
    12121 actttgaggc agctggtaac gctctatgat ccagtcgatt ttcagagaga cgatgcctga
    12181 gccatccggc ttacgatact gacacaggga ttcgtataaa cgcatggcat acggattggt
    12241 gatttctttt gtttcactaa gccgaaactg cgtaaaccgg ttctgtaacc cgataaagaa
    12301 gggaatgaga tatgggttga tatgtacact gtaaagccct ctggatggac tgtgcgcacg
    12361 tttgataaac cagggaaaag attcatagcc tttttcatcg ccggcatcct cttcagggcg
    12421 ataaaaaacc acttccttcc ccgcgaaact cttcaatgcc tgccgtatat ccttactggc
    12481 ttccgcagag gtcaatccga atatttcagc atatttagca acatggatct cgcagatacc
    12541 gtcatgttcc tgtagggtgc catcagattt tctgatctgg tcaacgaaca gatacagcat
    12601 acgtttttga tcccgggaga gactatatgc cgcctcagtg aggtcgtttg actggacgat
    12661 tcgcgggcta tttttacgtt tcttgtgatt gataaccgct gtttccgcca tgacagatcc
    12721 atgtgaagtg tgacaagttt ttagattgtc acactaaata aaaaagagtc aataagcagg
    12781 gataactttg cgaaaaaaca gcttcttctg agggcaattt gtcacagggt taagggcaat
    12841 ttgtcacaac accttctcta gaaccagcat ggataaaggc ctacaaggcg ctctaaaaaa
    12901 gaagatctaa aaactataaa aaaaataatt ataaaaatat ccccgtggat aagtggataa
    12961 ccccaaggga agttttttca ggcatcgtgt gtaagcagaa tatataagtg ctgttccctg
    13021 gtgcttcctc gctcactcga gggcttcgcc ctgtcgctcg actgcggcga gcactactgg
    13081 ctgtaaaagg acagaccaaa catcatggtt ctgtgttcat taggttgttc tgtccattgc
    13141 tgacataatc cgctccactt caacgtaaca ccgcacgaag atttctattg ttcctgaagg
    13201 catattcaaa tcgttttcgt taccgcttgc aggcatcatg acagaacact acttcctata
    13261 aacgctacac aggctcctga gattaataat gcggatctct acgataatgg gagattttcc
    13321 cgactgtctc gttcgcttct cagtggataa cagccagctt ctctgtttaa cagacaaaaa
    13381 cagcatatcc actcagttcc acatttccat ataaaggcca aggcatttat tctcaggata
    13441 attgtttcag catcgcaacc gcatcagact ccggcatcgc aaactgcacc cggtgccggg
    13501 cagccacatc cagcgcaaaa accttcgtgt agacttccgt tgaactgatg gacttatgtc
    13561 ccatcaggct ttgcagaact ttcagcggta taccggcata cagcatgtgc atcgcatagg
    13621 aatggcggaa cgtatgtggt gtgaccggaa cagagaacgt cacaccgtca gcagcagcgg
    13681 cggcaaccgc ctccccaatc caggtcctga ccgttctgtc cgtcacttcc cagatccgcg
    13741 ctttctctgt ccttcctgtg cgacggttac gccgctccat gggtattttc agtgttgcca
    13801 ccatcgtctg cagctggctg acgtaccagg agtcagagag cggaaccagc cggtgagtct
    13861 gctgaccggc gggcattctc cccgccgtcc tggcagcttt ttcggtccgt tgtttcaggg
    13921 tcgcaagctg cacaaacgga tacggaggcg tgagcgaaaa atccccccgc gtcagcgcta
    13981 gtgcttcatt aatacgcgcg ccggtgttcc acagagtggc cagcagcatc ttgcggcgca
    14041 gatccgggac ataatgaagc agggcactca cctcgggagc cagcagatat ttcggcagtt
    14101 catcatgaac catcgacatc tggcggagtg ccagagctgc cggataatca atggcaacag
    14161 gaagttgtgc agactgtccg gcagaataca ctgccggtac catggctgca gactggctgt
    14221 gtataacgga gcctgacatt tatattcccc agaacatcag gttaatggca tttttgatgt
    14281 cattttctcg gtggctgaga tcagccactt cctccccgat aacggagacc ggcacactgg
    14341 ccatatcggt ggtcatcatg cgccagcttt catccccgac atgcaccacc gggtaaagct
    14401 cacgggagac cttatctgac aacagacgtg cactggccag ggggatcacc atccgtcgcc
    14461 caggcgtgtc aataatgtca ctctggacat ccacaaacag acgataacgg ctctctcttt
    14521 tataggtgta aaccttaaac tgcatttcac cagtccctgt tctcgtcggc aaaagagccg
    14581 ttcatttcaa taaaccgggc gacctcagcc atcccttcct gattttctgc ctgccagcgt
    14641 tcggcacgca gacgacgggc ttcattctgc agggtggtgc ttaccagccc ggagatattg
    14701 acatcatatg ccttgagcaa ctgatagctg tcactgtcga cggtgactgt aatgcgctgc
    14761 ttcataatgc acctcatctt acatactctc tgtacaccat taagtataca ccagtattac
    14821 gctataacat gcctccggca acggaatatt gttatccagc tattattaac accaccatca
    14881 ataactgacc tgaaaagtaa tcatgacaat aataacctgc aatgtagtaa ccatgataaa
    14941 ttacaggatg actgtttttc tatgatccga tttttatcgg attcaggatt ttccggaagt
    15001 gaatcaggat cagtgaataa gcgaagcgat cttttctgcc gctgatgact ggctcgggaa
    15061 cacgggaaga aacacaacat acagtgtcat gtcagcggag cgggacacca catcctgtga
    15121 aagcggacca gcgggcggca gcgaaggatc cgcggatccg gaaccaccag aaaccggatc
    15181 tgcacgggga aagagagaaa ataacatagg ctgaacatat ccatatgcct gacatctgcc
    15241 tatactaaac atatgcacac acccggtgca atgaacatca ttccggatat gcatcacata
    15301 tccacactta cccgggagag aatcatgaga accgtatcca tttttaaaaa tggcaacaac
    15361 cgtgctatcc gccttccacg cgatctggat tttgaggggg tgagcgagct ggagatcgtc
    15421 cgggaagggg acagcatcat tctgcgcccc gtccggccga cctggggctc attcctggag
    15481 ctagaaaagg ccgatccgga ctttatgacg gagcgcgagg acgttgtcag cgacgaagga
    15541 cgagttaacc tgtgaacaag atctatatgc tcgacacgaa catctgctcg ttcatcatgc
    15601 gcgagcaacc tgaagcattg cttaagcacc tggagcagtc ggtgctgcgc ggtcaccgta
    15661 tcgtggtctc ggccatcacc tactccgaga tgcgcttcgg tgccaccggt ccgaaggcct
    15721 cgccacgcca cgtgcaactg gttgacgcgt tctgtgagag gctcgatgcc gtcctgccgt
    15781 gggaccgcgc cgcggtggat gcgaccacgg agattaaggt ggcactgcgt ctcgccggca
    15841 cgccgatcgg tccgaacgac acggcgatag ccggacacgc catcgctgcc tgtgccattc
    15901 tggtgacgaa taatgtgaga gagtttgagc gggtaccggg tcttgtgctg gaagactggg
    15961 taagataacg ctgtaaaaca aaacaggcgg tcaggcgcgg ccggccgctc tttcaggcag
    16021 cggtatataa aggaataaaa aaatgccact gatcacgcgg cttatgctgc aaaacttcaa
    16081 aaagtttccg gaactggacc tgcgcttcag caacgatcgt aacattctgg ttggggacaa
    16141 tgagtccggg aaaagcacta ttctgctggc tcttgacctt gtgctgagtg acagcaggca
    16201 tcgggttgag gcgctggggg tggaatcgct cctgtcacag tcagcagtca ggcattttca
    16261 ggaaggtgag cgccgtgccg atcagttacc cgtgctgacc gctgacgttt tcctgagtaa
    16321 tgggggagag cctgacctga acggcaggca aaatctggcg ggtatcgatg cggatggtct
    16381 cagaatgcgc attgctccca tgatggagga atacggtcag gatatacacc atgttttgca
    16441 gcaggatcct gataattttc cctatgaata ctattccgtg cagttcagca cattctccgg
    16501 tggtcatttc gcaggcttca gacgctatct gcgccatctg ttcttagaca gtgcacgcat
    16561 tgataacgag catgccgcac aggagtatac gcgcacagtt tacagcgtca atgtgccggt
    16621 ggccgatcgg taccggcttg aaaacagtta ccggcaacag aaaatgcact tctgcgcccg
    16681 gcatctgtcc gccataaacg acacgctgaa aacgtatcag tttggcgtgc gttccggcgc
    16741 taaatcaggt cttgaggcga acctggacat tactgaggac ggtatttcca ttcgtcaccg
    16801 cggaaaagga agacagtgtt tcatcaaaac ggagtttgcg ctgcagcggc atcagcagca
    16861 ggggggagag atccacgcgc tgttgcttga ggagccggag aatcatctca gccatgtcag
    16921 tatgaagagg ctggttaatc agcttgccac ggaacggcag acgcaggtgt ttattgccac
    16981 acacagtagc catatctcct cccgcctcga cctacgtaag gctattctcc tcggagctac
    17041 ccggccggta ctgatgaatg aactttccgc tgagactgcc gccttcttca tgaaagcacc
    17101 ggataataac gtgctggaat ttgcgctggc cagacgcgtg ctgctcgtgg agggggatgc
    17161 tgagtttatt ctgatcgagg ccttttatca ccgcctgtat ggcagggcac cggaggatga
    17221 cggggttcac atcatcgcta tcggcggaac gagtttccgt cgttatcttg aactggcccg
    17281 tcttctggaa aatcgtgtcg cggcccttcg cgacaatgac ggcaactatc agcaaaattg
    17341 cgatgaacgc tatgctgacg tgctttgttc ccgctcccgg gtatttgctg accacgacaa
    17401 cagccgctcc acatttgaaa tctgcctgta tcaggataat gccgacctgt gtgatgcgct
    17461 tttccgcgga acccgccgga cactcacggt tcaggattac atgctggcca ataaggcaga
    17521 agcagcattc cagctgttac agttgcacgc cgaaaagctg accgttcctg attatatcca
    17581 ggaggcactg gcatggataa gagagtgata tttgcggttg ccggctcggg taaaaccacg
    17641 ctgctgatac gtcggttaag agaggaccgg cggacgctga tcctgacctt caccgtaaat
    17701 aatgaagcac atctgcgggc gcagattatc agacgctttg gctacatacc gtacgggatc
    17761 cgtgtgatga cctggtttga gtttctgcac ggtttctgtt ttcgcccttt cctgcaggag
    17821 caactgtcat cgcgtggtct gagcttcaac cagccccctt ccagaatacc gcgcacgaat
    17881 atccggcatt atcaggatcc cgccggacgg ctgtatcacc ggcggctcgc acacctgctg
    17941 acagcccggg ggttgctgcc agatatccgt acccgacttg cccgttacta cgatgagttg
    18001 ttcgttgatg aagtccagga ctttgccggc catgacttta attttctgct ggagctatgc
    18061 cgcgcggaaa tctcagtgct gtgctgcggg gatttttatc agcatacctt tgacacaagc
    18121 cgcgacggta acgtcaatgc tacgctgcat gaagacataa cccgatacga ggctcgcttc
    18181 agggctgcgg gtatcatggt ggattgtgag acgctcagcc ggacatggcg ctgttcagct
    18241 acagtgtgtg agttcattac cggacaactg aacattcgca tttcggctca tggaacacat
    18301 accacccaga ttgaaatcgt cacggatgaa gcgcgttcag cggccctgca cgcggacaac
    18361 acgatgatca agctcttcta tcgcgaacat caccgttacg gatgccactc aatgaactgg
    18421 gggggcagta aaggactcga ccactttcag gacgtctgca tcgtgatggg ggccaaccac
    18481 tggatgcgcc tcatccaaca gaagctggca gcacttccac catcatcccg taacaggcta
    18541 tacgtggcct gctcacgggc acggggcaac atctatttta ttccggaaag ccatcttcgg
    18601 agattcagaa actaagtcag cggcttctca actgggcaca agccggtaaa aagtagtcaa
    18661 cgacaaaact tcaggccgaa aaatgaggct ccggtttcgc cggaaaccgg acctgcgtgg
    18721 agggaaaccc gcagatgata tgatatttat cattaatcgc ataataaatc ctggcctgat
    18781 atttacaggc agagaaataa atcattcgat atatgatttt atcgtcatca gccattaacc
    18841 ccccaggaag
//
LOCUS       DAPOAV010000084        18679 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.084, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000084 DAPOAV010000000
VERSION     DAPOAV010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18679)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18679)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18679
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.084"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(103..366)
                     /gene="cedA"
                     /locus_tag="RN951_003425"
     CDS             complement(103..366)
                     /gene="cedA"
                     /locus_tag="RN951_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division activator CedA"
                     /protein_id="HDX2528375.1"
                     /translation="MRLVKPVMKKPLRQQNRQIISYVPRTEPAPPEHAIKMDSFRDVW
                     MLRGKYVAFVLMGESFLRSPAFTVPESAQRWANQIRQEGEVTE"
     gene            549..2810
                     /gene="katE"
                     /locus_tag="RN951_003426"
     CDS             549..2810
                     /gene="katE"
                     /locus_tag="RN951_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase HPII"
                     /protein_id="HDX2528376.1"
                     /translation="MSQHNEKNPHQHQSPLHDSSEAKPGMDSLAPEDGSHRPAAEPTP
                     PGAQPTAPGSLKAPDTRNEKLNSLEDVRKGSENYALTTNQGVRIADDQNSLRAGSRGP
                     TLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLSDITKADFLSDPNKIT
                     PVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFV
                     HAVKPEPHWAIPQGQSAHDTFWDYVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHT
                     FRLINAEGKATFVRFHWKPLAGKASLVWDEAQKLTGRDPDFHRRELWEAIEAGDFPEY
                     ELGFQLIPEEDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQAAFH
                     PGHIVPGLDFTNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHR
                     MGIDTNPANYEPNSINDNWPRETPPGPKRGGFESYQERVEGNKVRERSPSFGEYYSHP
                     RLFWLSQTPFEQRHIVDGFSFELSKVVRPYIRERVVDQLAHIDLTLAQAVAKNLGIEL
                     TDDQLNITPPPDVNGLKKDPSLSLYAIPDGDVKGRVVAILLNDEVRSADLLAILKALK
                     AKGVHAKLLYSRMGEVTADDGTVLPIAATFAGAPSLTVDAVIVPCGNIADIADNGDAN
                     YYLMEAYKHLKPIALAGDARKFKATIKVADQGEEGIVEADSADGSFMDELLTLMAAHR
                     VWSRIPKIDKIPA"
     gene            complement(3068..3817)
                     /gene="chbG"
                     /locus_tag="RN951_003427"
     CDS             complement(3068..3817)
                     /gene="chbG"
                     /locus_tag="RN951_003427"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HDX2528377.1"
                     /translation="MERLLIVNADDFGLSKGQNYGIIEACRNGIVTSTTALVNGQAID
                     HAVQLSRDEPSLAIGMHFVLTMGKPLTAMPGLTRDGVLGKWIWQLAEEDALPLEEITQ
                     ELVSQYLRFIELFGRKPTHLDSHHHVHMFPQIFPIVARFAAEQGIALRADRQMAFDLP
                     VNLRTTQGFSSAFYGEEISESLFLQVLDDAGHRGDRSLEVMCHPAFIDNTIRQSAYCF
                     PRLTELDVLTSASLKGAIAQRGYRLGSYRDV"
     gene            complement(3830..5182)
                     /gene="celF"
                     /locus_tag="RN951_003428"
                     /gene_synonym="chbF"
     CDS             complement(3830..5182)
                     /gene="celF"
                     /locus_tag="RN951_003428"
                     /gene_synonym="chbF"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDX2528378.1"
                     /translation="MSQKLKVVTIGGGSSYTPELLEGFIKRYHELPVSELWLVDVEGG
                     KPKLDIIFDLCQRMIDNAGVPMKLYKTLDRREALKDADFVTTQLRVGQLPARELDERI
                     PLSHGYLGQETNGAGGLFKGLRTIPVIFDIVKDVEELCPNAWVINFTNPAGMVTEAVY
                     RHTGFKRFIGVCNIPIGMKMFIRDVLMLKDSDDLSIDLFGLNHMVFIKDVLVNGKSRF
                     AELLDGVASGQLKASSVKNIFDLPFSEGLIRSLNLLPCSYLLYYFKQKEMLAIEMGEY
                     YKGGARAQVVQKVEKQLFELYKNPELKVKPKELEQRGGAYYSDAACEVINAIYNDKQA
                     EHYVNIPHHGQIDNIPADWAVEMTCKLGRDGATPHPRITHFDDKVMGLIHTIKGFEIA
                     ASNAALSGEFNDVLLALNLSPLVHSDRDAELLAREMILAHEKWLPNFADCIAELKKAH
                     "
     gene            complement(5287..6129)
                     /gene="chbR"
                     /locus_tag="RN951_003429"
     CDS             complement(5287..6129)
                     /gene="chbR"
                     /locus_tag="RN951_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ChbR"
                     /protein_id="HDX2528379.1"
                     /translation="MMQPVINAPEIATAREQQLFNGKNFHVFIYNKTESISGLHQHDY
                     YEFTLVLTGRYFQEINGKRVLLERGDFVFIPLGSHHQSFYEFGATRILNVGISKRFFE
                     QHYLPLLPYCFVASQVYRTNNAFLTYVETVISSLNFRETGLEEFVEMVTFYVINRLRH
                     YREEQVIDDVPQWLKSTVEKMHDKEQFSESALENMVALSAKSQEYLTRATQRYYGKTP
                     MQIINEIRINFAKKQLEMTNYSVTDIAFEAGYSSPSLFIKTFKKLTSFTPKSYRKKLT
                     EFNQ"
     gene            complement(6137..6487)
                     /gene="chbA"
                     /locus_tag="RN951_003430"
     CDS             complement(6137..6487)
                     /gene="chbA"
                     /locus_tag="RN951_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIA"
                     /protein_id="HDX2528380.1"
                     /translation="MMDLDNIPDTQTEAEELEEVVMGLIINSGQARSLAYAALKQAKQ
                     GDFAAAKAMMDQSRMALNEAHLVQTKLIEGDAGEGKMKVSLVLVHAQDHLMTSMLARE
                     LITELIELHEKLKA"
     gene            complement(6538..7896)
                     /gene="chbC"
                     /locus_tag="RN951_003431"
     CDS             complement(6538..7896)
                     /gene="chbC"
                     /locus_tag="RN951_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIC"
                     /protein_id="HDX2528381.1"
                     /translation="MSNVIASLEKVLLPFAVKIGKQPHVNAIKNGFIRLMPLTLAGAM
                     FVLINNVFLSFGEGSFFYSLGIRLDASTIETLNGLKGIGGNVYNGTLGIMSLMAPFFI
                     GMALAEERKVDALAAGLLSVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVA
                     EMFTFIVRRNWVIKLPDSVPASVSRSFSALIPGFIILSVMGIIAWALNTWGTNFHQII
                     MDTISTPLASLGSVVGWAYVIFVPLLWFFGIHGALALTALDNGIMTPWALENIATYQQ
                     YGSVEAALAAGKTFHIWAKPMLDSFIFLGGSGATLGLILAIFIASRRADYRQVAKLAL
                     PSGIFQINEPILFGLPIIMNPVMFIPFVLVQPILAAITLAAYYMGIIPPVTNIAPWTM
                     PTGLGAFFNTNGSVAALLVALFNLGIATLIYLPFVVVANKAQNAIDKEESEEDIANAL
                     KF"
     gene            complement(7981..8301)
                     /gene="chbB"
                     /locus_tag="RN951_003432"
     CDS             complement(7981..8301)
                     /gene="chbB"
                     /locus_tag="RN951_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIB"
                     /protein_id="HDX2528382.1"
                     /translation="MEKKHIYLFCSAGMSTSLLVSKMRAQAEKYEVPVIIEAFPETLA
                     GEKGQNADVVLLGPQIAYMLPEIQRLLPNKPVEVIDSLLYGKVDGLGVLKAAVAAIKK
                     AAAN"
     gene            complement(8600..8938)
                     /gene="osmE"
                     /locus_tag="RN951_003433"
     CDS             complement(8600..8938)
                     /gene="osmE"
                     /locus_tag="RN951_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotically-inducible lipoprotein OsmE"
                     /protein_id="HDX2528383.1"
                     /translation="MNKNMAGILSAAAVLTMLAGCTAYDRTKDQFVQPVVKDVKKGMS
                     RAQVAQIAGKPSSEVSMIHARGTCQTYILGQRDGKAETYFVALDDTGHVINSGYQTCA
                     EYDTDPQAAK"
     gene            9140..9967
                     /gene="nadE"
                     /locus_tag="RN951_003434"
     CDS             9140..9967
                     /gene="nadE"
                     /locus_tag="RN951_003434"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HDX2528384.1"
                     /translation="MTLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLV
                     LGISGGQDSTLAGKLCQMAINELRLETGNESLQFIAVRLPYGVQADEQDCQDAIAFIQ
                     PDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGT
                     DHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALACPEHLYKKAPTADLEDDR
                     PSLPDEVALGVTYDNIDDYLEGKNVPQQVARTIENWYLKTEHKRRPPITVFDDFWKK"
     gene            10197..11084
                     /gene="cho"
                     /locus_tag="RN951_003435"
     CDS             10197..11084
                     /gene="cho"
                     /locus_tag="RN951_003435"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease Cho"
                     /protein_id="HDX2528385.1"
                     /translation="MVRRLTSPRLEFEAAAIYEYPEHLRSFLNDLPTRPGVYLFHGES
                     DTMPLYIGKSVNIRSRVLSHLRTPDEAAMLRQSRRISWICTAGEIGALLLEARLIKEQ
                     QPLFNKRLRRNRQLCALQLNEKRVDVVYAKEVDFSRAPNLFGLFANRRAALQALQTIA
                     DEQKLCYGLLGLEPLSRGRACFRSALKRCAGACCGKESHEEHALRLRQSLERLRVVCW
                     PWQGAVALKEQHPEMTQYHIIQNWLWLGAVNSLEEATTLIRTPAGFDHDGYKILCKPL
                     LSGNYEITELDPANDQRAS"
     gene            complement(11044..11619)
                     /gene="ves"
                     /locus_tag="RN951_003436"
     CDS             complement(11044..11619)
                     /gene="ves"
                     /locus_tag="RN951_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="environmental stress-induced protein Ves"
                     /protein_id="HDX2528386.1"
                     /translation="MEYFDMRKMSVNLWRNAAGETREICTFPPAKRDFYWRASIASIA
                     ANGEFSLFPGMERIVTLLEGGEMLLESADRFNHTLKPFQPFAFAADQVVKAKLTAGQM
                     SMDFNIMTRLDVCKAKVRIAERTFTTFGSRGGVVFVINGAWQLGDKLLTTDQGACWFD
                     GRHTLRLLQPQGKLLFSEINWLAGHSPDQVQ"
     gene            complement(11822..12307)
                     /gene="spy"
                     /locus_tag="RN951_003437"
     CDS             complement(11822..12307)
                     /gene="spy"
                     /locus_tag="RN951_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-independent periplasmic protein-refolding
                     chaperone"
                     /protein_id="HDX2528387.1"
                     /translation="MRKLTALFVASTLALGAANLAHAADTTTAAPADAKPMMHHKGKF
                     GPHQDMMFKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKVKAE
                     AQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLTERPAAKGKMPATA
                     E"
     gene            complement(12637..13605)
                     /gene="astE"
                     /locus_tag="RN951_003438"
     CDS             complement(12637..13605)
                     /gene="astE"
                     /locus_tag="RN951_003438"
                     /EC_number="3.5.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate desuccinylase"
                     /protein_id="HDX2528388.1"
                     /translation="MDNFLALTLTGKKPVITEREINGVRWRWLGDGVLELTPLTPPQG
                     ALVISAGIHGNETAPVEMLDALLGAISHGEIPLRWRLLVILGNPPALKQGKRYCHSDM
                     NRMFGGRWQLFAESGETCRARELEQCLEDFYDQGKESVRWHLDLHTAIRGSLHPQFGV
                     LPQRDIPWDEKFLTWLGAAGLEALVFHQEPGGTFTHFSARHFGALACTLELGKALPFG
                     QNDLRQFAVTASAIAALLSGESVGIVRTPPLRYRVVSQITRHSPSFEMHMASDTLNFM
                     PFEKGTLLAQDGEERFTVTHDVEYVLFPNPLVALGLRAGLMLEKIS"
     gene            complement(13598..14941)
                     /gene="astB"
                     /locus_tag="RN951_003439"
     CDS             complement(13598..14941)
                     /gene="astB"
                     /locus_tag="RN951_003439"
                     /EC_number="3.5.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-succinylarginine dihydrolase"
                     /protein_id="HDX2528389.1"
                     /translation="MNAWEVNFDGLVGLTHHYAGLSFGNEASTRHRFQVSNPRLAAKQ
                     GLLKMKALADAGFPQAVIPPHERPFIPVLRQLGFSGSDEQVLEKVARQAPHWLSSVSS
                     ASPMWVANAATIAPSADTLDGKVHLTVANLNNKFHRSLEAPVTESLLKAIFNDEEKFS
                     VHSALPQVALLGDEGAANHNRLGGHYGEPGMQLFVYGREEGNDTRPSRYPARQTREAS
                     EAVARLNQVNPQQVIFAQQNPDVIDQGVFHNDVIAVSNRQVLFCHQQAFARQSQLLAN
                     LRARVNGFMAIEVPATQVSVSDTVSTYLFNSQLLSRDDGSMMLVLPQECREHAGVWGY
                     LNELLAADNPISELKVFDLRESMANGGGPACLRLRVVLTEEERRAVNPAVMMNDTLFN
                     ALNDWVDRYYRDRLTAADLADPQLLREGREALDVLSQLLNLGSVYPFQREGGGNG"
     gene            complement(14938..16416)
                     /gene="astD"
                     /locus_tag="RN951_003440"
     CDS             complement(14938..16416)
                     /gene="astD"
                     /locus_tag="RN951_003440"
                     /EC_number="1.2.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate-semialdehyde dehydrogenase"
                     /protein_id="HDX2528390.1"
                     /translation="MTLWINGDWITGQGASRVKRNPVSGEVLWQGNDADAAQVEQACR
                     AARAAFPRWARLSFAERHAVVERFAALLESNKAELTAIIARETGKPRWEAATEVTAMI
                     NKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALL
                     AGNTIIFKPSELTPWSGEAVMRLWQQAGLPPGVLNLVQGGRETGQALSALEDLDGLLF
                     TGSANTGYQLHRQLSGQPEKILALEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQR
                     CTCARRLLLKSGAQGDAFLARLVAVSQRLTPGNWDDEPQPFIGGLISEQAAQQVVTAW
                     QQLEAMGGRPLLAPRLLQAGTSLLTPGIIEMTGVAGVPDEEVFGPLLRVWRYDTFDEA
                     IRMANNTRFGLSCGLVSPEREKFDQLLLEARAGIVNWNKPLTGAASTAPFGGIGASGN
                     HRPSAWYAADYCAWPMASLESDSLTLPATLNPGLDFSDEVVR"
     gene            complement(16413..17447)
                     /gene="astA"
                     /locus_tag="RN951_003441"
     CDS             complement(16413..17447)
                     /gene="astA"
                     /locus_tag="RN951_003441"
                     /EC_number="2.3.1.109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine N-succinyltransferase"
                     /protein_id="HDX2528391.1"
                     /translation="MMVIRPVERSDVSALMQLASKTGGGLTSLPANEATLSARIERAI
                     KTWQGELPKSEQGYVFVLEDSETGTVAGICAIEVAVGLNDPWYNYRVGTLVHASKELN
                     VYNALPTLFLSNDHTGSSELCTLFLDPDWRKEGNGYLLSKSRFMFMAAFRDKFNDKVV
                     AEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLS
                     QEAQDVIGQVHPQTAPARAVLEKEGFRYRNYIDIFDGGPTLECDIDRVRAIRKSRLVE
                     VAEGQPAQGDFPACLVANENYHHFRVVLVRTDPATERLILTAAQLDALKCHAGDRVRL
                     VRLCAEEKTA"
     gene            complement(17444..18664)
                     /gene="astC"
                     /locus_tag="RN951_003442"
     CDS             complement(17444..18664)
                     /gene="astC"
                     /locus_tag="RN951_003442"
                     /EC_number="2.6.1.11"
                     /EC_number="2.6.1.81"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylornithine/acetylornithine transaminase"
                     /protein_id="HDX2528392.1"
                     /translation="MSQPITRENFDEWMIPVYAPAPFIPVRGEGSRLWDQQGKEYIDF
                     AGGIAVNALGHAHPELREALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFC
                     NSGAEANEAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAP
                     LPADIRHAAYNDINSASALIDDSTCAVIVEPIQGEGGVVPASNAFLQGLRELCNRHNA
                     LLIFDEVQTGVGRTGELYAYMHYGVTPDLLTTAKALGGGFPVGALLATEECARVMTVG
                     THGTTYGGNPLASAVAGKVLELINTPEMLNGVKQRHDWFVERLNTINHRYGLFSEVRG
                     LGLLIGCVLNADYAGQAKQISQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDR
                     FAAACEHFVSRGSS"
BASE COUNT         4687 a         5047 c         4452 g         4493 t
ORIGIN      
        1 tcaaaggcag ctttttgtta caggtggttt gaatgaatgt agcaacgaaa tacagaattt
       61 caggtcatgt aactcccggc aaaaccggga ggtatgtaat ccttactcag tcacttcccc
      121 ttcctggcgg atctgatttg cccaacgttg ggcagattca ggcacagtaa acgccggtga
      181 gcgcagaaat gactctccca tcagtacaaa cgcaacatat ttgccacgca gcatccagac
      241 atcacgaaac gaatccatct ttatcgcatg ttctggcggc gcgggttccg tgcgtgggac
      301 atagctaata atctggcggt tttgctggcg gagcggtttc ttcattactg gcttcactaa
      361 acgcatatta aaaatcagaa aaactgtagt ttagccgatt tagcccctgt acgtcccgct
      421 ttgcgtgtat ttcataacac cgtttccaga atagtctccg aagcgggatc tggctggtgg
      481 tctatagtta gagagttttt tgaccaaaac agcggccctt tcagtaataa attaaggaga
      541 cgagttcaat gtcgcaacat aacgaaaaga acccacatca gcaccagtca ccactacacg
      601 attccagcga agcgaaaccg gggatggact cactggcacc tgaggacggc tctcatcgtc
      661 cagcggctga accaacaccg ccaggtgcac aacctaccgc cccagggagc ctgaaagccc
      721 ctgatacgcg taacgaaaaa cttaattctc tggaagacgt acgcaaaggc agtgaaaatt
      781 atgcgctgac cactaatcag ggcgtgcgca tcgccgacga tcaaaactca ctgcgtgccg
      841 gtagccgtgg tccaacgctg ctggaagatt ttattctgcg cgagaaaatc acccactttg
      901 accatgagcg cattccggaa cgtattgttc atgcacgcgg atcagccgct cacggttatt
      961 tccagccata taaaagctta agcgatatta ccaaagcgga tttcctctca gatccgaaca
     1021 aaatcacccc agtatttgta cgtttctcta ccgttcaggg tggtgctggc tctgctgata
     1081 ccgtgcgtga tatccgtggc tttgccacca agttctatac cgaagagggt atttttgacc
     1141 tcgttggcaa taacacgcca atcttcttta tccaggatgc gcataaattc cccgattttg
     1201 ttcatgcggt aaaaccagaa ccgcactggg caattccaca agggcaaagt gcccacgata
     1261 ctttctggga ttatgtttct ctgcaacctg aaactctgca caacgtgatg tgggcgatgt
     1321 cggatcgcgg catcccccgc agttaccgca ccatggaagg cttcggtatt cacaccttcc
     1381 gcctgattaa tgccgaaggg aaggcaacgt ttgtacgttt ccactggaaa ccactggcag
     1441 gtaaagcctc actcgtttgg gatgaagcac aaaaactcac cggacgtgac ccggacttcc
     1501 accgccgcga gttgtgggaa gccattgaag caggcgattt tccggaatac gaactgggct
     1561 tccagttgat tcctgaagaa gatgaattca agttcgactt cgatcttctc gatccaacca
     1621 aacttatccc ggaagaactg gtgcccgttc agcgtgtcgg caaaatggtg ctcaatcgca
     1681 acccggataa cttctttgct gaaaacgaac aggcggcttt ccatcctggg catatcgtgc
     1741 cgggactgga cttcaccaac gatccgctgt tacagggacg tttgttctcc tataccgata
     1801 cacaaatcag tcgtcttggt gggccgaatt tccatgagat tccgattaac cgtccgacct
     1861 gcccttacca taatttccag cgtgacggca tgcatcgcat ggggatcgac actaacccgg
     1921 cgaattacga accgaactcg attaacgata actggccgcg cgaaacaccg ccggggccga
     1981 aacgcggcgg ttttgaatca taccaggagc gcgtggaagg caataaagtt cgcgagcgca
     2041 gcccatcgtt tggcgaatat tattcccatc cgcgtctgtt ctggctaagt cagacgccat
     2101 ttgagcagcg ccatattgtc gatggtttca gttttgagtt aagcaaagtc gttcgtccgt
     2161 atattcgtga gcgcgttgtt gaccagctgg cgcatattga tctcactctg gcccaggcgg
     2221 tggcgaaaaa tctcggtatc gaactgactg acgaccagct gaatatcacc ccacctccgg
     2281 acgtcaacgg tctgaaaaag gatccatcct taagtttgta cgccattcct gacggtgatg
     2341 tgaaaggtcg cgtggtagcg attttactta atgatgaagt gagatcggca gaccttctgg
     2401 ccattctcaa ggcgctgaag gccaaaggcg ttcatgccaa actgctctac tcccgaatgg
     2461 gtgaagtgac tgcggatgac ggtacggtgt tgcctatagc cgctaccttt gccggtgcac
     2521 cttcgctgac ggtcgatgcg gtcattgtcc cttgcggcaa tatcgcggat atcgctgaca
     2581 acggcgatgc caactactac ctgatggaag cctacaaaca ccttaaaccg attgcgctgg
     2641 cgggtgacgc gcgcaagttt aaagcaacaa tcaaggtcgc tgaccagggt gaagaaggga
     2701 ttgtggaagc tgacagcgct gacggtagtt ttatggatga actgctaacg ctgatggcag
     2761 cacaccgcgt gtggtcacgc attcctaaga ttgacaaaat tcctgcctga tgggaggcgg
     2821 cgcaattgcg ccgcctcaaa tgatttacat agtgcgcttt gtttatgccg gatgcggcgt
     2881 gaacgcctta tccggcctac aaaactgtgc aaattcaata tattgcagga aacacgtagg
     2941 cctgataagc gaagcgcatc aggcagtttt gcgtttgtca gcagtctcaa gcggcgcagt
     3001 tacgccgcct ttgtaggaat taatcgccgg atgcaaggtt cacgccgcat ctggcaaaca
     3061 tcctcactta cacatcccga taactcccca accgataacc acgctgagcg atagcacctt
     3121 tcaacgacgc tgatgtcaac acatccagct ccgttaagcg tgggaaacag taagcactct
     3181 gacggatagt attatcgata aacgccggat gacacatcac ctccagcgaa cgatcacccc
     3241 gatggcctgc gtcatccagc acttgcagga acagcgactc actgatctct tcaccgtaga
     3301 atgcactgct gaatccctgg gtagtgcgca ggttgaccgg caaatcaaac gccatctgac
     3361 gatccgcccg caacgcaatg ccctgctctg ccgcaaacct ggcaacaatc gggaaaatct
     3421 gcgggaacat atgcacatga tgatggctat caagatgcgt aggtttgcgt ccaaatagct
     3481 caatgaaacg caaatactga ctgacaagct cctgagtaat ttcttccagc ggtaaagcat
     3541 cttcttctgc caactgccag atccattttc ccagcacacc atcgcgggtt aaccccggca
     3601 tagctgtcag tggcttaccc atagtaagga caaagtgcat ccctatggcc agactcggtt
     3661 catcacgact caactgcacc gcatggtcaa tagcctgccc attcaccagc gccgtcgtcg
     3721 acgtgacaat cccattgcga caggcctcga taatgccgta gttctgacct ttgcttaagc
     3781 caaaatcatc ggcattaaca atcagtaagc gttccataat cagcctcggt taatgtgctt
     3841 ttttaagctc tgcgatgcag tcggcaaagt ttggcagcca tttctcgtgc gccagaatca
     3901 tctcgcgtgc cagcagctca gcatcgcgat cggaatgcac caacggacta aggtttagcg
     3961 ccagtaacac atcgttaaat tctccgctaa gtgcggcgtt actggcagca atctcgaagc
     4021 ctttaatggt gtgaatcagc cccattactt tatcatcgaa atgcgtaatg cgcggatgtg
     4081 gcgtcgcgcc atcgcgcccc agcttacagg tcatttctac tgcccagtct gccggaatat
     4141 tatcaatctg cccatgatgc gggatattaa cgtaatgttc tgcttgcttg tcgttgtaga
     4201 tagcgttgat cacttcgcat gctgcatcag agtaataagc cccaccgcgc tgttccagtt
     4261 ctttcggctt aactttcagc tcaggatttt tatacagctc aaaaagttgt ttctcgactt
     4321 tctgtactac ctgcgctcgt gcgccgcctt tgtagtattc gcccatttca atagccagca
     4381 tctctttctg cttgaagtaa tacagcagat aagaacatgg cagcagattc aacgaacgaa
     4441 ttaagccctc actaaatggc agatcgaaaa tattttttac agaggacgct tttaactgcc
     4501 ctgacgccac accatcaagc aattcggcaa agcgcgactt gccatttacc agcacatcct
     4561 taatgaacac catatggttg aggccgaaca aatcgataga taaatcatcg ctgtctttca
     4621 gcatcagaac atcgcgaata aacatcttca tgccgatcgg aatattacac acgccgataa
     4681 agcgtttaaa tccggtatga cgataaacgg cttcagtgac cattcccgcc gggttagtga
     4741 agttaatcac ccatgcattc ggacaaagtt cttcgacatc ttttacgatg tcaaaaatca
     4801 ccggaatggt acgcagacct ttaaacaaac cgcccgcgcc gttggtttcc tgaccaagat
     4861 aaccatgact taatggaata cgttcatcca gttcacgcgc cggtaattgg ccaacgcgca
     4921 gttgggtagt aacgaaatca gcatctttca atgcttcgcg gcgatccagc gttttataaa
     4981 gcttcatcgg gacgccagcg ttatcaatca tccgttggca gagatcgaaa ataatatcca
     5041 gtttcggttt accaccttcg acatccacca gccataattc gctgaccggc aattcgtgat
     5101 aacgcttaat aaatccttcc agtaactccg gggtatagct gctcccgcca ccaatagtga
     5161 cgacttttaa tttctggctc ataatttctc ccttcagtac agaatactga tatctggcat
     5221 atctgccccc ccggacataa ataatccagc aacaggacag atatgtgaat tgtcaggtat
     5281 aacgacttac tgattaaatt cagtcaattt cttacgatag ctcttaggcg taaaggacgt
     5341 taatttctta aacgttttaa taaacaaact cgggctacta taaccggcct caaacgcaat
     5401 atccgtcact gaatagttgg tcatttccag ttgttttttg gcaaaattaa tacggatttc
     5461 attaataatc tgcattggcg ttttgccata atatcgttga gtcgctcgcg tcaaatattc
     5521 ctgtgatttg gctgacaacg ccaccatatt ctccagcgcc gattcactaa actgctcttt
     5581 atcatgcatc ttttctaccg tacttttcag ccactgcggt acatcatcaa tcacctgttc
     5641 ttcgcggtaa tgacgtaaac ggttaatgac ataaaaagta accatctcaa caaactcttc
     5701 cagccctgtt tcgcggaaat tcaatgaaga aatcactgtt tccacatagg tgagaaaagc
     5761 gttattggtc cggtatacct gcgaagcgac aaagcaataa ggcaacaatg gcaggtaatg
     5821 ctgctcaaaa aagcgtttac tgatcccaac gttcaatatg cgcgtggcac caaactcata
     5881 aaaactttga tggtgcgaac ctaacggaat aaaaacaaaa tcgccccgtt ccagtaacac
     5941 gcgcttaccg ttaatctcct ggaaataacg cccggttaat accagagtaa attcataata
     6001 gtcgtgctga tgcagtccgc tgatactctc agttttgtta tagataaaca catggaagtt
     6061 tttgccatta aacaactgct gttctcgggc agtggcaatt tccggcgcgt taatcactgg
     6121 ctgcatcatc gactccttat gccttcagtt tttcatgaag ctcaattaat tcagtaatca
     6181 gttcacgcgc aagcatggac gtcattaaat gatcctgagc gtggaccagc accagactca
     6241 ctttcatctt accttcgccc gcatcgcctt caatcagttt cgtctgtacc agatgcgctt
     6301 cattcaatgc catccgtgac tgatccatca tggcttttgc tgcggcaaaa tcgccctgct
     6361 tcgcctgttt cagtgccgca tacgccaggc tgcgcgcttg tccggagttg atgatcagcc
     6421 ccatcaccac ttcttccagc tcttcagctt ccgtttgcgt atcgggaatg ttatcgagat
     6481 ccatcataca tcgttcctct cttttcttac cggcacgatt acccgtaccg gcatcgatta
     6541 aaatttcagg gcgttagcga tatcttcttc gctctcttct ttatcaatcg cattttgtgc
     6601 tttgttagcc accacaacaa agggcagata aattaacgtt gcgatgccaa ggttgaagag
     6661 tgcgaccagc aatgcggcga cgctaccgtt ggtgttaaag aaggctccca gaccggttgg
     6721 catggtccac ggtgcaatat tggtcaccgg aggaataatg cccatgtagt acgctgcgag
     6781 ggtgattgcc gccagaatcg gttgtaccag tacaaacggg ataaacatca ccgggttcat
     6841 gataattggc agaccaaaca gaatcggttc gttaatctgg aagatgccgg acggcagcgc
     6901 cagttttgcc acctgacgat aatcagcacg gcgagaggcg ataaagatag ccaggatcag
     6961 gcctaaagtc gcaccactgc ccccaaggaa aataaaggag tccagcatcg gcttggccca
     7021 gatatggaag gtcttaccgg ctgccagcgc cgcttcgacg gaaccatatt gctgataggt
     7081 cgcgatattt tccagtgccc acggcgtcat aatgccgttg tccagtgcgg tcagcgccag
     7141 cgcgccatga ataccgaaga accagagcag tggaacaaag atcacatagg cccagcccac
     7201 cacgctaccc aacgatgcca gtggggttga gatggtatcc ataatgatct gatggaagtt
     7261 ggtgccccag gtattcaacg cccaggcaat aatccccatc acggaaagaa taataaagcc
     7321 gggaattaat gccgagaagg aacgcgatac tgaagcaggt acgctgtcgg gcagtttaat
     7381 gacccaattg cggcggacaa taaaggtaaa catttctgcc accaccaggc caataataat
     7441 cccggagatg atattcgccc cacctaacca gtttgcacca accgcatagg cctcaccgac
     7501 actatatggg gtgacggtca taaatgctgc aacggataac aacccagccg ccagcgcatc
     7561 gactttacgc tcttctgcca gcgccatgcc aataaagaac ggtgccatta aagacattat
     7621 tcctaatgtt ccgttatata cgttgccgcc aatacctttc agaccattaa gtgtttcaat
     7681 ggttgaggcg tcgaggcgaa tacctaagga ataaaaaaac gacccctccc caaagcttag
     7741 aaaaacgttg ttaattaata caaacatggc ccccgcaagg gttaacggca ttaagcgaat
     7801 aaagccattt ttgattgcat taacgtgtgg ctgctttcct attttaactg caaaagggag
     7861 gagtaccttt tcaagcgatg caataacatt actcatagaa aaataccctt aaaaaccgca
     7921 atttaaatat tgcggtattg atttatgaaa taactctttg acgggaaaat ttaaaataaa
     7981 ttaatttgct gcggcttttt taatcgctgc aaccgcagcc ttaagcacgc ctaaaccatc
     8041 gactttgcca taaagcagcg agtcaattac ttcaaccggt ttgttgggta acaaacgctg
     8101 gatttcgggc aacatataag caatctgcgg ccctaataac acgacatcgg cattctgacc
     8161 tttttcacca gccagtgttt ccggaaatgc ttcaataatg accggaactt catatttttc
     8221 tgcctgtgcg cgcatttttg ataccagtaa agaggtagac atgcccgcag aacaaaacag
     8281 ataaatgtgt ttcttttcca taaaactgcc ctcatcgacg attatctgtc agccagacac
     8341 tccgcaagcc ttaacctgct tccatgctct gggtaacttg cgaaaccaac atgacttttt
     8401 ttgtggctga aaggagtata cggtatagac ctgagcaata gtatttcttt gaccttataa
     8461 attgtttctc cttgacctgt ggttatgacc ctcttcacat ttcgggcaaa taattcgcga
     8521 agataattaa gaactcaggc caaaaaaaac cggcgcaatg gccggtttcc gttgttactc
     8581 aagctttcag acgaattgat tacttcgcag cctgtggatc agtgtcgtat tcagcacagg
     8641 tctgataacc ggagttgatg acatgtccgg tatcatctaa cgcgacaaag taggtttctg
     8701 ctttaccatc acgttgaccc aggatgtagg tctggcaagt accgcgagca tggatcatgc
     8761 tcacttcaga cgaaggttta cccgcaattt gtgcaacctg cgcccggctc atgccttttt
     8821 tgacgtcttt caccacaggc tgtacaaact ggtctttggt acgatcataa gccgtacaac
     8881 ccgccagcat ggttaatacc gccgctgcac tcagaattcc tgccatattc ttgttcatat
     8941 tccgtcctct tgtttatcag cgtgttagat aagcctggaa tacattgggc gctttttcaa
     9001 gcccgtgaac gaaacggctc cgctttcaga ggattcctgt atgacgtttt aaccaccatt
     9061 cagcccgctg tcgcttgtcg tttcagtagc aacgggttag ctttaaggaa gttttgtctt
     9121 ttctgtctgg aggggttcaa tgacattgca acaacaaata ataaaggcgc tgggcgcaaa
     9181 accgcagatt aatgctgaag aggaaattcg tcgtagtgtc gattttctga aaagctacct
     9241 gcaaacttat ccgttcatta aatcactggt gctcgggatc agcggcggtc aggactccac
     9301 gcttgccgga aagctgtgcc agatggcgat taatgagctg cgcctggaaa ccggcaacga
     9361 atcactgcaa tttattgccg tacgcctgcc ctatggtgtt caggccgacg aacaagattg
     9421 ccaggatgcc attgccttta ttcaaccgga tcgcgtatta accgttaata tcaagggcgc
     9481 ggtattggcc agcgaacagg cattgcggga agcaggcatt gaactgagcg attttgtccg
     9541 tggcaatgaa aaagcgcgtg agcggatgaa agcacaatat agcattgcgg gtatgaccag
     9601 cggtgtcgtg gtgggcaccg atcatgcagc agaagccatt accggattct tcactaaata
     9661 tggtgacggc ggtacggaca ttaatccgct gtatcgtctc aacaaacgtc agggtaaaca
     9721 gttactggcg gcattagctt gcccggaaca cctttataag aaagcgccaa cggccgatct
     9781 ggaagatgat cgcccttctc tgccagatga agtggcactc ggcgtgacct atgacaatat
     9841 cgacgactat ctggaaggga aaaacgtacc tcaacaggtc gccagaacaa tagagaactg
     9901 gtatctgaaa accgaacata aacgccgtcc gccaattacc gttttcgatg atttctggaa
     9961 aaagtaataa tttgcacata ttggattgtg cgaaaaagag taatttgttc acgccggatg
    10021 cggcgtgaac gccttattcg acctataaaa ctatgcaaat tcaatacatt gcaggagtcg
    10081 aataggcctg acaggcgtag cacgtcagac ggtgtaacct ttgtcatcga cccgcctctt
    10141 ttttaatcgc ttcccgcctg ttacactgga tagataacca gcattcggag tcaacagtgg
    10201 tacggcgttt aacttctccg cggctcgaat ttgaagctgc ggcaatttat gaatatcccg
    10261 aacatttacg ttcattcctt aatgacttac ccacccgacc aggggtgtat ctgtttcatg
    10321 gtgaaagtga caccatgccg ctctatatcg gcaaaagcgt taacatccgc agccgcgtcc
    10381 tttctcattt acgtaccccg gatgaagccg ccatgctacg gcaatcccga cggatcagct
    10441 ggatatgtac cgccggtgaa atcggcgctc tgctccttga agcgcgatta atcaaagaac
    10501 aacagccgct gtttaataaa cggttgcgcc gcaatcgcca gctctgtgcc ctgcaattaa
    10561 atgaaaagcg cgtcgatgtg gtgtatgcca aagaggtgga tttttcacga gcccccaacc
    10621 tgtttggcct gtttgccaat aggcgcgcag ctttgcaagc attgcagacc atcgctgatg
    10681 aacaaaaact ttgttatggc ctgctgggac tggaaccgtt aagtcgcggt cgtgcatgtt
    10741 ttcgttcagc gctaaaacgt tgcgccggag catgctgcgg taaagagagc catgaggaac
    10801 atgcgctacg cttgcgccag tctctggagc gtttgcgggt ggtgtgttgg ccttggcaag
    10861 gggcggtggc gctgaaagaa cagcacccgg aaatgactca atatcatatt attcaaaact
    10921 ggctgtggct gggggcggtt aattcgctgg aagaagcgac aacgttaatt cggacacccg
    10981 ccgggtttga tcacgacggt tataaaattc tttgtaagcc gctgctttcc ggtaactatg
    11041 aaattactga acttgatccg gcgaatgacc agcgagccag ttgatttcac tgaacaacag
    11101 tttaccttgc ggttgtaaaa gccgcagggt gtgcctgcca tcgaaccagc acgcgccctg
    11161 gtcggtagtg agcaatttat cgcccagttg ccacgccccg ttaatcacaa acaccacccc
    11221 gccgcgtgag ccaaaggtag taaacgtacg ttcggcaatt ctgactttcg ccttacagac
    11281 atccaggcgt gtcatgatgt tgaaatccat cgacatctgc cctgccgtca gtttcgcttt
    11341 taccacctgg tccgctgcaa aggcaaaagg ctggaacggt tttaaggtat ggttaaagcg
    11401 gtctgcgctt tcaaggagca tctcgccgcc ttccagcaac gtcactatcc tttccatgcc
    11461 gggaaacaaa gaaaactccc cattcgccgc gatggatgca atgctggcac gccagtaaaa
    11521 atcacgtttt gccggtggga acgtgcaaat ttcgcgcgtt tcaccggcag catttcgcca
    11581 cagattcacc gacattttac gcatatcaaa gtattccata ctcgctcccg gcccgttctt
    11641 ttcattgtta tcgttcaggt aaccgtggat ggttatcggc aactcgggtg atttacgtta
    11701 gtggtgatca ggcttttttt acaactgttt gagaagagaa aagaaaaccg ccgatcctgt
    11761 ccaccgcatt actgcaaggt agtggacaag accggcggtc ttaagttttt tggctgaaag
    11821 attattcagc agttgcaggc attttacctt ttgccgctgg acgttctgtc agacgcttct
    11881 caaaattagc attaaattgc tttttctgtt ccggcgtcag gatgttgtaa attttgttct
    11941 gggtttccat gtgcgccagc atgttagctt tgcgctgttc ttccattttt gcgatctgcg
    12001 cttcagcttt tactttatcg aaggtatcgc tggcaatgat gtcatgcatt gcgcggcgtt
    12061 cttccagcgg cggacgtttc atctggtcac gctggccttt catgatttcg cggatctgct
    12121 gtttctgcgc gtcggtcagg ttcaggtctt tgaacatcat gtcctgatgc ggaccgaact
    12181 tgcctttgtg gtgcatcatc ggcttcgcgt cagccggtgc tgcggtagtg gtgtctgcgg
    12241 catgggccag gttagccgcg ccaagagcca gggtagaggc aacaaacagt gcagttaatt
    12301 tacgcatatt ctatatcctt cctttcagtt atttattacg gctttcttaa gtagcgtgcc
    12361 gtgttgacga gattaacttt actgacttta gcgtcaatta atcagagcaa cggtaaaaca
    12421 atgaaagtgt aaaaaacact tttgcgccaa ttatggagaa aaaaagaaaa tttgatggag
    12481 agtgatgaga gaatattaca acacgatgat tttgcagaga ttatgaagaa ctataccgga
    12541 tgactggtga taaataaagc aaataaccag gattaatctg tattaattta taagaaagca
    12601 acttaatacc cgcagaatga tttctgcggg taagtattag cttatttttt cgagcattaa
    12661 tcccgcgcgt aatcccaacg ctaccaacgg attagggaat aacacatact ctacatcatg
    12721 ggttacggta aaacgttcct ctccgtcctg cgccagcaat gttcctttct caaacggcat
    12781 aaaattcagc gtgtcacttg ccatatgcat ttcgaaggac ggcgagtggc gagtaatttg
    12841 cgaaaccacc cgataacgga gcggcggtgt tctcacgata ccgacactct caccagatag
    12901 cagcgcagca attgcgctgg cagttactgc aaactggcga agatcgtttt gcccaaaggg
    12961 caacgctttg ccaagttcca gcgtacaggc cagcgcgcca aaatgtctgg cgctgaaatg
    13021 ggtaaacgta ccaccaggtt cctgatggaa caccagcgcc tccagccccg ccgcacccag
    13081 ccacgtcaga aatttctcgt cccagggaat gtcgcgttgc ggtaatacac cgaactgcgg
    13141 atgcaaggag ccacgaattg cggtatgtag atcaaggtgc cagcgcacag attctttgcc
    13201 ctggtcataa aaatcttcca ggcactgttc cagttcgcgc gcccgacagg tttctccgct
    13261 ttcagcaaat agctgccaac gaccgccaaa cattcgattc atatcgctat ggcaataacg
    13321 tttcccttgc ttcagcgcag gaggattccc gaggatcacc agcaaccgcc aacgtaacgg
    13381 gatctcgccg tgagatatcg cgccaagcaa cgcgtccagc atctccacag gtgccgtctc
    13441 attaccgtgt attcccgctg aaatcaccag tgcgccttgc ggtggcgtta atggcgtcag
    13501 ttccagcaca ccatcgccca gccagcgcca gcgaacgccg ttgatttctc gctcggtgat
    13561 aaccggtttt ttacccgtta aggtcagagc aagaaaatta tccattgccc cctccctcgc
    13621 gctggaacgg ataaaccgaa ccgagattca gtaattggct caatacatcc agtgcttccc
    13681 gcccttcgcg cagcaattgc gggtcggcca gatcggcagc agtaaggcga tcgcggtagt
    13741 aacgatccac ccagtcattg agcgcattaa acagcgtatc gttcatcatc accgccggat
    13801 tcaccgcccg gcgttcttct tctgtcaata ccacccgcaa ccgcaggcac gccgggccgc
    13861 cgccattcgc catgctttca cgtaaatcaa agacttttag ttcgctaatc gggttgtcag
    13921 cggcaaggag ttcattgaga taaccccata ctccggcgtg ttcccgacac tcctgaggca
    13981 gcaccaacat catggaacca tcatcgcggc tcagcagttg gctgttaaac agataggtag
    14041 acaccgtatc agacacggaa acctgagttg ccggaacttc tatcgccata aaaccattga
    14101 cccgcgcacg caggtttgcc agtaactgtg actggcgagc gaacgcctgt tggtggcaaa
    14161 acagcacctg gcggttactc acggcaatca cgtcattatg aaaaacgccc tggtcgataa
    14221 cgtccgggtt ttgctgggcg aaaatcacct gttggggatt cacctgattc agccttgcca
    14281 ccgcctcgct ggcttcgcga gtctgtcgcg ccggataacg ggaaggccgg gtatcattgc
    14341 cttcttctcg cccgtagaca aaaagttgca tacccggttc accgtaatga ccgccgagac
    14401 gattgtggtt tgccgccccc tcatcaccga gcaacgctac ctgtggcaac gccgaatgga
    14461 cgctaaattt ctcttcgtcg ttaaaaatcg cttttaacag cgattcagtg acgggcgctt
    14521 ccagcgaacg gtgaaattta ttgttcaggt tggcaacggt gagatgcact ttgccatcca
    14581 gcgtatcggc agatggcgcg atcgttgccg cattggctac ccacattggc gaagcggaac
    14641 tgacgctgga aagccagtgc ggtgcctggc gtgcaacttt ttccagtacc tgctcatcgc
    14701 taccactgaa tcccaactga cgcagcaccg gaataaacgg acgctcgtgc ggcgggatca
    14761 cggcctgggg gaatcccgca tcggcaaggg ctttcatttt cagtaagccc tgcttcgccg
    14821 ccagtcgcgg gttagacacc tgaaaacggt gacgggtaga ggcttcatta ccaaacgaca
    14881 ggcccgcgta atgatgcgtc agccctacca gcccgtcgaa attgacttcc caggcgttca
    14941 tcgcaccacc tcatcggaaa aatccagccc ggggttaagc gtggcgggca atgttaacga
    15001 gtccgactcc aggctcgcca tcggccatgc gcagtaatct gcggcatacc aggcgctggg
    15061 gcgatggtta ccggaagcac caatgccgcc gaatggcgcg gtactggcag caccggtaag
    15121 cggtttgttc cagttaacaa tccccgcccg cgcctccagc aacagttgat cgaacttttc
    15181 ccgctcgggg gaaaccagac cgcaagagag tccgaagcga gtgttattcg ccattcgaat
    15241 cgcttcatcg aaagtatcat aacgccagac gcgcaataac ggtccgaaca cctcttcatc
    15301 tggtacgcca gcaacgcctg tcatttcaat gatccccggc gtcagcaacg atgtccctgc
    15361 ttgtaataag cgcggcgcaa gcaggggtcg tccgcccatc gcttccagtt gctgccatgc
    15421 agtaaccacc tgctgtgcgg cctgttcaga aatcagcccg ccaataaacg gctgcggttc
    15481 gtcatcccag ttgcccggcg ttaatcgctg gctgacggca accagacgag caagaaacgc
    15541 atcgccctgc gccccgcttt tcagcaataa acggcgggcg caggtgcagc gttgaccggc
    15601 tgtgacaaac gccgactgaa tggtcagatg gacagccgcg tcgatatccg ccacctcatc
    15661 gataattagc ggattattac cgcccatctc aagggcgaga attttctccg gctgaccgga
    15721 gagctggcga tgcaactggt agcctgtatt ggcgctaccg gtaaacagca aaccgtcgag
    15781 atcctccagc gcactcagcg cctgacccgt ttcacgcccg ccctgcacca ggttcagcac
    15841 gcctggcggc aagccagcct gctgccataa acgcattacc gcttcgccac tccacggtgt
    15901 cagttcgctg ggtttaaaga taatggtgtt acctgccagc aatgccggaa cgatatgtcc
    15961 gttcggcaaa tgaccaggga aattatacgg cccaaacacc gccagcacgc cgtgcgggcg
    16021 atgtcgcagg ctcgccgcgc cgtccggcat ttcactacgc tgctcgccgg tacgaacgtg
    16081 atacgcctta attgatatcg cgattttatt gatcatcgcc gtcacttcgg ttgccgcttc
    16141 ccagcgcggc ttacccgttt ctctggcaat aatcgcggtt aattcggctt tattgctttc
    16201 cagcagtgcg gcaaagcgtt cgacaacggc atgacgttca gcaaatgaaa gccgcgccca
    16261 gcgcggaaac gccgcacggg ctgcccgaca agcctgctcg acctgagcgg catcggcatc
    16321 attgccttgc cataacacct cgcccgatac cggattacgc ttcacacgcg atgcgccctg
    16381 gcccgttatc cagtcaccgt taatccataa agtcatgctg ttttctcctc tgcgcacagg
    16441 cgcaccagac gaacgcgatc cccggcgtgg catttgaggg catccagttg tgcggcggtt
    16501 aaaatcaaac gctcggttgc cggatcggta cgcaccagca ccacgcggaa atggtgataa
    16561 ttttcattgg cgaccaggca ggctgggaaa tcgccctgcg caggctgccc ttctgccact
    16621 tccaccagcc gacttttacg gatggcgcgc acgcggtcga tgtcacactc aagcgtcggc
    16681 ccaccgtcaa agatgtcgat atagttacgg tagcgaaaac cttctttctc cagcaccgcg
    16741 cgggcaggcg cggtttgcgg atgtacctga ccgatgacgt cctgggcttc ctgggataaa
    16801 aagtgggtat agatcggatg tttcggcatc agttctgcaa taaatgcctt ttgcccggtg
    16861 ccgcagagaa aatcggcgcg gctaaaatcc atcgaaaaga agcgtttacc gaggctttgc
    16921 cagaacggtg aatagccgtg ttcgtcaatc accccgcgca tttcagcaac cactttgtca
    16981 ttaaacttgt cgcgaaaagc cgccataaac ataaagcgcg atttcgacag caaatagccg
    17041 ttgccctctt tgcgccagtc cgggtcgaga aacagcgtgc acagctcgct gctgccggtg
    17101 tgatcgttac tgagaaacag cgtcggcaat gcgttataga cattcagctc ttttgaggcg
    17161 tgaaccaacg tgccgacgcg atagttgtac cagggatcgt tcagcccaac cgccacctca
    17221 atggcacaaa tccccgccac ggtgcctgtc tcgctatctt ccagcacgaa cacatagccc
    17281 tgctcacttt tgggcagttc gccttgccag gttttgattg ccctttcgat acgcgccgaa
    17341 agcgtggctt cattggcggg aagcgacgtc aggccgccgc ccgttttgct ggcaagctgc
    17401 atcagcgccg agacatctga tcgctcaacg ggacggatga ccatcatgat gaacctcggc
    17461 taacaaagtg ttcgcaagca gctgcaaagc gatccagtcc ggtcgtcacc tcttcttcgc
    17521 tgacattgag cgcaggcgca aaacgcacca cgttgccacc cgcaatcagt accatcacgc
    17581 ctgctttcgc cgcttcctga gagatctgtt tcgcttgccc ggcgtaatcg gcattcagta
    17641 cacagccaat cagcaaacct aagccgcgaa cttcactgaa caaaccatag cggtgattaa
    17701 tagtattaag acgctcaaca aaccagtcgt gacgctgttt aacgccatta agcatctctg
    17761 gtgtgttgat gagctccagc actttgcctg ccaccgccga ggccagcgga ttaccgccat
    17821 aggtggtgcc atgagtgcca acggtcatca cgcgggcgca ctcttcggtt gccaacaacg
    17881 caccgaccgg gaaaccgccg cccagcgctt tggcggtagt taacagatca ggcgtcacgc
    17941 cgtagtgcat ataggcatac agttccccgg tgcgcccgac gccggtttgt acttcatcaa
    18001 aaatcaacag cgcattgtgg cggttacaca attcacgcag accttgtaaa aacgcgttgc
    18061 tggctggcac cacaccgcct tccccctgga tgggttcgac aatcaccgca caggtagagt
    18121 cgtcaatcag cgcgctggca gagttaatat cgttatatgc agcatgacga atatccgccg
    18181 gcagtggcgc aaaatcctgt gaataggctg gctgcccacc cgcactgaca gtaaacagcg
    18241 tgcgaccatg aaacgcattt ttgaacgcca cgatgccgct cttatggctg ccgtagcggt
    18301 cgtgagcgaa tttacgcgcc agttttagcg ccgcttcgtt ggcttccgca ccggagttac
    18361 aaaagaagac gcgatcggca aacgtggcgt cgatcaattt tttcgccagt cgcagtaccg
    18421 gctcgttggt gtaaccgttg ccggtatgcc agaacttact cgcctgttcg ttcagcgctt
    18481 cacgcagttc cggatgcgca tggcccagcg cgttcaccgc aatgccaccc gcgaagtcga
    18541 tatactcttt cccctgctga tcccacaagc gcgaaccttc gccacgtacc ggtataaagg
    18601 gtgccggagc gtaaacaggt atcatccatt catcaaagtt ttcacgcgta attggctgag
    18661 acatagcgac ctctacagt
//
LOCUS       DAPOAV010000085        18176 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.085, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000085 DAPOAV010000000
VERSION     DAPOAV010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18176
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.085"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..550)
                     /locus_tag="RN951_003443"
     CDS             complement(<1..550)
                     /locus_tag="RN951_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDX2528393.1"
                     /translation="MRADKSLSPFEIRVYRHYRIVHGTRVALAFLLTFLIIRLFTIPE
                     STWPLVTMVVIMGPISFWGNVVPRAFERIGGTVLGSILGLIALQLELISLPLMLVWCA
                     AAMFLCGWLALGKKPYQGLLIGVTLAIVVGSPTGEINTALWRSGDVILGSLLAMLFTG
                     IWPQRAFIHWRIQLAKSLTEYNR"
     gene            complement(748..1221)
                     /gene="sbmC"
                     /locus_tag="RN951_003444"
     CDS             complement(748..1221)
                     /gene="sbmC"
                     /locus_tag="RN951_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor SbmC"
                     /protein_id="HDX2528394.1"
                     /translation="MNYEIKQEDKRTVAGFHLVGPWEQTVKKGFEQLMMWVDSKNIVP
                     KEWVAVYYDNPDETPAEKLRCDTVVTVPNNFTLPENSEGVILTEISGGQYAVAVARVV
                     GDDFAKPWYQFFNSLLQDSAYEMLPKPCFEVYLNNGAEDGYWDIEMYVAVQPKHH"
     gene            complement(1340..2506)
                     /gene="dacD"
                     /locus_tag="RN951_003445"
     CDS             complement(1340..2506)
                     /gene="dacD"
                     /locus_tag="RN951_003445"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416514.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase DacD"
                     /protein_id="HDX2528395.1"
                     /translation="MKRRLIIAASLFVFNLSSGFAAENIPFSPQPPEIHAGSWVLMDY
                     TTGQILTAGNEHQQRNPASLTKLMTGYVVDRAIDSHRITPDDIVTVGRDAWAKDNPVF
                     VGSSLMFLKEGDRVSVRDLSRGLIVDSGNDACVALADYIAGGQRQFVEMMNNYAEKLH
                     LKDTHFETVHGLDAPGQHSSAYDLAVLSRAIIHGEPEFYHMYSEKSLTWNGITQQNRN
                     GLLWDKTMNVDGLKTGHTSGAGFNLIASAVDGQRRLIAVVMGADSAKGREEEAKKLLR
                     WGQQNFTTVQILHRRKKVGTERIWYGDKENIALGTEQEFWMVLPKAEIPHIKAKYTLD
                     GKELTAPISAHQRVGEIELYDRDKQVAHWPLVTLESVGEGSMFSRLSDYFHHKA"
     gene            2715..4142
                     /gene="sbcB"
                     /locus_tag="RN951_003446"
     CDS             2715..4142
                     /gene="sbcB"
                     /locus_tag="RN951_003446"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease I"
                     /protein_id="HDX2528396.1"
                     /translation="MMNDGKQQSTFLFHDYETFGTHPALDRPAQFAAIRTDNEFNVIG
                     EPEVFYCKPADDYLPQPGAVLITGITPQEARAKGENEATFAARIHSLFTVPKTCILGY
                     NNVRFDDEVTRNVFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGINWPENDDG
                     LPSFRLEHLTKANGIEHSNAHDAMADVYATIAMAKLVKTRQPRLFDYLFTHRNKHKLM
                     ALIDVPQMKPLVHVSGMFGAWRGNTSWVAPLAWHPENRNAVIMVDLAGDISPLLELDS
                     DTLRERLYTAKADLGDNAAVPVKLVHINKCPVLAQANTLRPEDADRLGINRQHCLDNL
                     KILRENPQVREKVVAIFAEAEPFTPSDNVDAQLYNGFFSDADRAAMKIVLETEPRNLP
                     ALDITFVDKRIEKLLFNYRARNFPGTLDYAEQQRWLEHRRQIFTSEFLQGYAEEIQML
                     AQQYADDKEKVALLKALWQYAEEIV"
     gene            complement(4185..4412)
                     /locus_tag="RN951_003447"
     CDS             complement(4185..4412)
                     /locus_tag="RN951_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA family protein"
                     /protein_id="HDX2528397.1"
                     /translation="MAIKKLDVVTQVCPFPLIEAKAALAEMASGDELVIEFDCTQATE
                     AIPQWAAEEGHAITDYQQIGDAAWSITVQKA"
     gene            complement(4426..5484)
                     /gene="yeeE"
                     /locus_tag="RN951_003448"
     CDS             complement(4426..5484)
                     /gene="yeeE"
                     /locus_tag="RN951_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transport protein YeeE"
                     /protein_id="HDX2528398.1"
                     /translation="MFSMILSGLICGALLGFVMQRGRFCLTGGFRDMYIAKNNRMFYA
                     LLIAISVQSVGVFALIQAGLLTYEAGAFPWLGTVIGGYLFGLGIVLAGGCATGTWYRA
                     GEGLIGSWIALFTYMVMSAVMRSPHASGLNQTLQHYSTEHNSIAETFNLSVWPLVTVL
                     LVITLWVVMKELKKPKLKVATLPPRRTGIAHILFEKRWHPFVTAVLIGLIALLAWPLS
                     EATGRMFGLGITSPTANILQFLVAGDVKYINWGVFLVLGIFVGSFIAAKASREFRVRA
                     ADAQTTLRSGLGGVLMGFGASIAGGCSIGNGLVMTAMMTWQGWIGLVFMILGVWTASW
                     LVYVRPQRKARLATAAAN"
     gene            complement(5663..7021)
                     /gene="plaP"
                     /locus_tag="RN951_003449"
     CDS             complement(5663..7021)
                     /gene="plaP"
                     /locus_tag="RN951_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416518.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine/proton symporter PlaP"
                     /protein_id="HDX2528399.1"
                     /translation="MSHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVS
                     GLTDGHVPTAYAFALIAILFTALSYGKLVRRYPSAGSAYTYAQKSISPTVGFMVGWSS
                     LLDYLFAPMINILLAKIYFEALVPSIPSWMFVVALVAFMTAFNLRSLKSVANFNTVIV
                     VLQVVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFD
                     GISNLSEETKDAERVIPRAIFLTALIGGMIFIFATYFLQLYFPDISRFKDPDASQPEI
                     MLYVAGKAFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGVFPKSFFGYVHPKWR
                     TPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLK
                     DHFQYLFLPMCGALTVGALWVNLEESSMVLGLIWAAIGLIYLACVTKSFRNPVPQYED
                     VA"
     gene            complement(7011..7073)
                     /gene="yoeI"
                     /locus_tag="RN951_003450"
     CDS             complement(7011..7073)
                     /gene="yoeI"
                     /locus_tag="RN951_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YoeI"
                     /protein_id="HDX2528400.1"
                     /translation="MGQFFAYATVITVKENDHVA"
     gene            complement(7288..8217)
                     /locus_tag="RN951_003451"
     CDS             complement(7288..8217)
                     /locus_tag="RN951_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416519.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX2528401.1"
                     /translation="MKPLLDVLMILDALEKEGSFAAASAKLYKTPSALSYTVHKLESD
                     LNIQLLDRSGHRAKFTRTGKMLLEKGREVLHTVRELEKQAIKLHEGWENELVIGVDDT
                     FPFSLLAPLIEAFYQHHSVTRLKFINGVLGGSWDALTQGRADIIVGAMHEPPSSSEFG
                     FSRLGDLEQVFAVAPHHPLALEEEPLNRRIIKRYRAIVVGDTAQAGASTASQLLDEQE
                     AITVFDFKTKLELQISGLGCGYLPRYLAQRFLDSGALIEKKVVAQTLFEPVWIGWNEQ
                     TAGLASGWWRDEILANSAIAGVYAKSDDGKSAI"
     gene            complement(8263..9087)
                     /locus_tag="RN951_003452"
     CDS             complement(8263..9087)
                     /locus_tag="RN951_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDX2528402.1"
                     /translation="MKKVAIVGLGWLGMPLAMSLSARGWQVTGSKTTQDGVEAARMSG
                     IDSYLLRMEPELVCDSDDLDALMDADALVITLPARRSGSGDEFYLQAVQELVDSALAH
                     RIPRIIFTSSTSVYGDAQGMVKETTPRNPVTNSGRVLEELEDWLHNLPGTSVDILRLA
                     GLVGPGRHPGRFFAGKTAPDGEHGVNLVHLEDVIGAITLLLQAPKGGHIYNICAPAHP
                     ARNVFYPQMARLLGLEPPQFRNSLDSGKGKIIDGSRICNELGFEYQYPDPLVMPLE"
     gene            complement(9170..9424)
                     /gene="yoeB"
                     /locus_tag="RN951_003453"
     CDS             complement(9170..9424)
                     /gene="yoeB"
                     /locus_tag="RN951_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YoeB"
                     /protein_id="HDX2528403.1"
                     /translation="MKLIWSEESWDDYLYWQETDKRIVKKINELIKDTRRTPFEGKGK
                     PEPLKHNLSGFWSRRITEEHRLVYAVTDDSLLIAACRYHY"
     gene            complement(9421..9672)
                     /gene="yefM"
                     /locus_tag="RN951_003454"
     CDS             complement(9421..9672)
                     /gene="yefM"
                     /locus_tag="RN951_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoeB-YefM toxin-antitoxin system antitoxin YefM"
                     /protein_id="HDX2528404.1"
                     /translation="MRTISYSEARQNLSATMMKAVEDHAPILITRQNGEACVLMSLEE
                     YNSLEETAYLLRSPANARRLMDSIDSLKSGKGTEKDIIE"
     gene            9956..10006
                     /gene="hisL"
                     /locus_tag="RN951_003455"
     CDS             9956..10006
                     /gene="hisL"
                     /locus_tag="RN951_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="his operon leader peptide"
                     /protein_id="HDX2528405.1"
                     /translation="MTRVQFKHHHHHHHPD"
     misc_feature    9982..10105
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00514"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="His leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00514"
     gene            10152..11051
                     /gene="hisG"
                     /locus_tag="RN951_003456"
     CDS             10152..11051
                     /gene="hisG"
                     /locus_tag="RN951_003456"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HDX2528406.1"
                     /translation="MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAE
                     NMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFG
                     GCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDKKGISFKSCLLNGSVEVAPR
                     AGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQ
                     GVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWE
                     TMEKLKALGASSILVLPIEKMME"
     gene            11057..12361
                     /gene="hisD"
                     /locus_tag="RN951_003457"
     CDS             11057..12361
                     /gene="hisD"
                     /locus_tag="RN951_003457"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HDX2528407.1"
                     /translation="MSFNTIIDWNSCTAEQQRQLLMRPAISASESITRTVNDILDNVK
                     ARGDEALREYSAKFDKTTVTALKVSAEEIAAASERLSDELKQAMAVAVKNIETFHTAQ
                     KLPPVDVETQPGVRCQQVTRPVDSVGLYIPGGSAPLFSTVLMLATPARIANCKKVVLC
                     SPPPIADEILYAAQLCGVQDVFNVGGAQAIAALAFGTESVPKVDKIFGPGNAFVTEAK
                     RQVSQRLDGAAIDMPAGPSEVLVIADSGATPDFVASDLLSQAEHGPDSQVILLTPAAD
                     MARRVAEAVERLLAELPRAETARQALNASRLIVTKDLAQCVEISNQYGPEHLIIQTRN
                     ARDLVDGITSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTATCSSLGLADFQKRMTV
                     QELSKEGFSALASTIETLAAAERLTAHKNAVTLRVNALKEQA"
     gene            12358..13428
                     /gene="hisC"
                     /locus_tag="RN951_003458"
     CDS             12358..13428
                     /gene="hisC"
                     /locus_tag="RN951_003458"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDX2528408.1"
                     /translation="MSTVTITDLARENVRNLTPYQSARRLGGNGDVWLNANEYPTAVE
                     FQLTQQTLNRYPECQPKAVIENYAQYAGVKPEQVLVSRGADEGIELLIRAFCEPGKDA
                     ILYCPPTYGMYSVSAETIGVECRTVPTLDNWQLDLQGISDKLDGVKVVYVCSPNNPTG
                     QLINPQDFRTLLELTRGKAIVVADEAYIEFCPQASLAGWLAEYPHLAILRTLSKAFAL
                     AGLRCGFTLANEEVINLLMKVIAPYPLSTPVADIAAQALSPQGIVAMRERVAQIIAER
                     EYLIAALKKISCVEQVFDSETNYILARFKASSAVFKSLWDQGIILRDQNKQPSLSGCL
                     RITVGTREESQRVIDALRAEQV"
     gene            13428..14495
                     /gene="hisB"
                     /locus_tag="RN951_003459"
     CDS             13428..14495
                     /gene="hisB"
                     /locus_tag="RN951_003459"
                     /EC_number="3.1.3.15"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707917.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     histidinol-phosphatase/imidazoleglycerol-phosphate
                     dehydratase HisB"
                     /protein_id="HDX2528409.1"
                     /translation="MSQKYLFIDRDGTLISEPPSDFQVDRFDKLAFEPGVIPELLKLQ
                     KAGYKLVMITNQDGLGTQSFPQADFDGPHNLMMQIFTSQGVQFDEVLICPHLPADECD
                     CRKPKVKLVERYLAEQAMDRANSYVIGDRATDIQLAENMGINGLRYDRETLNWPMIGE
                     QLTKRDRSAHVVRNTKETQIDVQVWLDREGGSKINTGVGFFDHMLDQIATHGGFRMEI
                     NVKGDLYIDDHHTVEDTGLALGEALKIALGDKRGICRFGFVLPMDECLARCALDISGR
                     PHLEYKAEFTYQRVGDLSTEMIEHFFRSLSYTMGVTLHLKTKGKNDHHRVESLFKAFG
                     RTLRQAIRVEGDTLPSSKGVL"
     gene            14495..15085
                     /gene="hisH"
                     /locus_tag="RN951_003460"
     CDS             14495..15085
                     /gene="hisH"
                     /locus_tag="RN951_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HDX2528410.1"
                     /translation="MNVVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFL
                     PGVGTAQAAMDQVRERELFDLIKACTQPVLGICLGMQLLGRRSEESNGVDLLGIIDED
                     VPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYG
                     EPFTAAVQKDNFYGVQFHPERSGAAGANLLKNFLEM"
     gene            15085..15822
                     /gene="hisA"
                     /locus_tag="RN951_003461"
     CDS             15085..15822
                     /gene="hisA"
                     /locus_tag="RN951_003461"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HDX2528411.1"
                     /translation="MIIPALDLIDGTVVRLHQGDYGKQRDYGNDPLPRLQDYAAQGAE
                     VLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRSEEDVAALLEAGVARVVVG
                     STAVKSPEMVKGWFERFGADALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETY
                     LPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQVAFQSSGGIGDIDDVAALRGTG
                     VRGVIVGRALLEGKFTVKEAIACWQNA"
     gene            15804..16580
                     /gene="hisF"
                     /locus_tag="RN951_003462"
     CDS             15804..16580
                     /gene="hisF"
                     /locus_tag="RN951_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HDX2528412.1"
                     /translation="MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYAEEGA
                     DELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSLEDAAKILSFGADKISI
                     NSPALADPTLITRLADRFGVQCIVVGIDTWYDAETGKYHVNQYTGDESRTRVTQWETL
                     DWVEEVQKRGAGEIVLNMMNQDGVRNGYDLEQLKKVREVCHVPLIASGGAGTMEHFLE
                     AFRDADVDGALAASVFHKQIINISELKAYLATQGVEIRIC"
     gene            16574..17182
                     /locus_tag="RN951_003463"
     CDS             16574..17182
                     /locus_tag="RN951_003463"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HDX2528413.1"
                     /translation="MLTEQQRHELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDK
                     TIESGKVTFFSRTKQRLWTKGETSGNFLNVVSIAPDCDNDTLLVLANPIGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVNDRFELTNEASDLMYHLLVLLQDQGLDLGEVIDNLKNRH"
     gene            complement(17221..>18176)
                     /gene="wbdC"
                     /locus_tag="RN951_003464"
     CDS             complement(17221..>18176)
                     /gene="wbdC"
                     /locus_tag="RN951_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_103927144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,
                     octacis-undecaprenol 3-alpha-mannosyltransferase WbdC"
                     /protein_id="HDX2528414.1"
                     /translation="HRVIYNKQLFEIASTPFSLKALKRFKQIKDDYDIINYHFPFPFM
                     DMLHLSARPDARTVVTYHSDIVKQKRLMKLYQPLQERFLASVDCIVASSPNYVASSQT
                     LKKYQDKTVVIPFGLEQHDVQHDPQRVAHWRETVGDNFFLFVGAFRYYKGLHILLDAA
                     ERSRLPVVIVGGGPLEAEVRREAQQRGLSNVVFTGMLNDEDKYILFQLCRGVVFPSHL
                     RSEAFGITLLEGARFARPLISCEIGTGTSFINQDKVSGCVIPPNDSQALVEAMNELWN
                     NEETSNRYGENSRRRFEEMFTADHMIDAYVNLYTTLLESKS"
BASE COUNT         4632 a         4811 c         4574 g         4159 t
ORIGIN      
        1 cccgattata ctcggtcaga ctttttgcca gttgaatgcg ccagtggatg aacgcccgtt
       61 gtggccagat accggtaaac aacattgcca gtaaagagcc gaggatcaca tcgccgcttc
      121 gccataacgc cgtattaatt tcacctgtcg gggaaccaac aacaattgcc agcgtcaccc
      181 caatcaataa accttgatac ggtttcttgc ccagcgccag ccaaccgcaa agaaacatag
      241 ccgccgcgca ccagactaac atcagcggta acgagattaa ctccagttgc agagcgataa
      301 gacctaaaat cgaccccaac accgtaccgc caatacgttc gaatgcgcga gggacaacgt
      361 tcccccagaa cgagattggc cccataatca ccaccatggt gaccagcggc caggtgcttt
      421 ccgggatagt aaacaggcgg ataatgagaa aagtgagcag gaatgccagc gcgacccgag
      481 taccatgcac aatgcggtaa tggcggtata cccggatttc aaacgggctt aatgacttat
      541 cggcacgcac gcagaaactc cgtaatgaag attaaaagcg ctcataactc atctgtcggc
      601 cagaaggcgc gcctctgaat tatccgacgg acaaaccggg aacagtgtaa tttcccggca
      661 ggagcgaaaa aattgaaagg cgcatcttac tcttttcgct ttcaaaaaaa gagtggtctt
      721 cgcgtcaaca caccgccctg agatgaatta gtgatgtttt ggctgcaccg caacatacat
      781 ttcgatatcc cagtacccat cttccgcgcc attgttcaag taaacctcga agcagggctt
      841 tggtaacatt tcataagcac tgtcctgcaa gaggctatta aagaactgat accagggttt
      901 agcaaaatca tcaccgacta cacgagccac cgccaccgca tattgaccac ctgaaatttc
      961 tgtcagaatg acgccctcac tgttttcggg gagcgtaaag ttattcggta ccgtcacgac
     1021 ggtgtcgcag cgtaattttt cggcgggtgt ttcatccgga ttgtcgtaat agacagcaac
     1081 ccactccttc ggcacaatat ttttgctatc tacccacatc atcaactgct caaaaccttt
     1141 ctttaccgtc tgttcccacg ggccaacgag atggaaacct gcaacggtac gtttatcttc
     1201 ctgcttaatc tcgtagttca tgacgcctcc attattactg tttttatata cagtatagtt
     1261 gcaatattaa aaccacaagg aatgagtgtt gattatgcga gcagactcgc actcctgcca
     1321 gtctgctgca aaagaaaggt caggccttat ggtggaaata atcactcagg cgagaaaaca
     1381 tgctgccttc cccgacagat tccagggtaa ccagcggcca gtgcgccacc tgtttatcac
     1441 ggtcgtaaag ttcaatttcc cctacccgct gatgggcgct aattggcgcg gtgagctctt
     1501 taccatcaag ggtatatttg gctttgatat gtggaatttc ggctttcggt agcaccatcc
     1561 agaactcttg ttccgttccc agggcgatat tttctttatc accataccag atgcgttccg
     1621 taccgacctt tttcctacgg tgcaaaattt gcaccgtagt aaagttttgt tgcccccaac
     1681 gcagtaattt ttttgcctct tcctcacgac cttttgcgct gtcagcaccc attaccactg
     1741 caatgaggcg acgctgcccg tctacagccg aagcaataag attaaacccg gcaccagaag
     1801 tatggcccgt tttcaggccg tcaacattca tggtcttatc ccacaataac ccgttacggt
     1861 tttgctgggt gataccgttc caggtgaggc ttttctcact gtacatatga taaaactcgg
     1921 gctcgccgtg gatgatagcg cgagaaagca cggctaaatc ataagccgag ctatgctggc
     1981 caggtgcatc cagaccatgc actgtttcaa aatgcgtatc cttgagatgc agcttctcgg
     2041 catagttgtt catcatttca acaaactgcc gttgcccacc ggcaatatag tcagccagag
     2101 caacacaagc gtcatttccg gaatccacaa ttaaacctcg gcttaaatca cgtaccgata
     2161 cgcgatcgcc ctctttcaaa aacatcagtg aagaaccgac aaacaccgga ttatctttcg
     2221 cccacgcatc acgccccacg gtgacaatat cgtctggcgt aatgcgatga ctatcgatag
     2281 cgcgatccac gacatagccc gtcatcagct ttgtcaggct ggcgggattg cgctgttgat
     2341 gctcattacc cgcagtgaga atctgaccgg tggtgtaatc catcaatacc caggacccgg
     2401 catgaatctc tggaggctga ggtgaaaaag gaatgttttc cgccgcaaaa ccagacgata
     2461 aattaaaaac gaacaaagaa gcagcaataa taagacggcg tttcaacagc aaaccctcag
     2521 gtgtttcaaa tagctgttct ttttacggaa atacttatga actggctgga ataaagtgca
     2581 agaaaatgtg actactatct catttttatc tgacatgatc tgttgtcact cgctgccaaa
     2641 ttgtcgcgct aaagctgatt agcacggtga tatttgatac tctggcagac agcagaaata
     2701 acggatttaa cctaatgatg aatgacggta agcaacaatc tacctttttg tttcacgatt
     2761 acgaaacctt tggaacgcac cccgcgttag atcgccctgc acagttcgca gccattcgca
     2821 ctgataacga attcaatgtc atcggcgaac ccgaagtctt ttactgcaag cccgcggatg
     2881 actatttacc ccagcctgga gcagtattaa ttaccggtat taccccgcag gaagcacggg
     2941 cgaaaggaga aaacgaagcc acgtttgccg cccgtattca ctcgcttttt accgtaccga
     3001 agacctgtat tctgggctac aacaatgtgc gtttcgacga cgaagtcaca cgcaacgttt
     3061 tttatcgtaa tttctacgat ccttacgcct ggagctggca gcatgataac tcgcgctggg
     3121 atttactgga tgttatgcgt gcctgttatg ccctgcgccc ggaaggaata aactggcctg
     3181 aaaatgatga cggtctaccg agctttcgcc ttgagcattt aaccaaagcg aatggtattg
     3241 aacatagcaa cgcccacgat gcgatggctg atgtgtacgc cactattgcg atggcgaaac
     3301 tggtaaaaac gcgtcagcca cgcctgtttg attatctctt tacccatcgt aataaacaca
     3361 aactgatggc gttgattgat gttccgcaga tgaaacccct ggttcacgtt tccggaatgt
     3421 ttggggcatg gcgtggcaat accagctggg tggcaccgct ggcgtggcat cctgaaaatc
     3481 gcaatgccgt aattatggtg gatttggcag gagacatttc gccattactg gagctggata
     3541 gcgacacatt gcgcgagcgt ttatataccg caaaagccga tcttggcgat aacgccgccg
     3601 ttccggttaa gctggtgcat atcaacaaat gtccggtact ggcccaggcg aatacgctac
     3661 gcccggaaga tgccgaccga ctgggaatta atcgtcagca ttgcctcgat aacctgaaaa
     3721 ttctgcgtga aaatccgcaa gtgcgcgaaa aagtggtggc gatattcgcg gaagccgaac
     3781 cgtttacacc ttcagataat gtggatgcac agctttataa tggctttttc agtgacgccg
     3841 atcgtgcagc aatgaaaatt gtgctggaaa ccgagccgcg taatttaccg gcactggata
     3901 tcacttttgt tgataaacga attgaaaagc tgttgttcaa ttatcgggcg cgcaacttcc
     3961 cggggacgct ggattatgcc gagcagcaac gctggctgga gcaccgccgc cagatcttca
     4021 cgtcagagtt tttacaaggc tatgcagaag agattcagat gctggcgcag cagtatgccg
     4081 acgataaaga aaaagtggcg ctgttaaaag cgctttggca gtacgcggaa gagattgtct
     4141 aatgtgaagc ctccgccgct ggtacggcgg aggacaattt tgagtcaggc tttttgaacg
     4201 gtgatgctcc acgctgcatc gccaatctgc tgataatcgg tgatggcatg cccttcttct
     4261 gccgcccact gtgggattgc ttcagttgcc tgggtgcaat caaactcaat taccaactca
     4321 tcgccgctgg ccatttctgc cagtgctgct tttgcttcta tgagtggaaa cggacagacc
     4381 tgcgtcacca catccagctt tttaatcgcc atctttacac cttacttaat ttgccgcagc
     4441 agttgccagt cgtgccttac gctgcggtcg aacatacaca agccaggacg cagtccagac
     4501 tccgagaatc ataaatacaa ggccaatcca gccctgccag gtcatcattg cagtcatgac
     4561 cagtccatta ccgatagagc aaccacctgc aatgctggca ccgaagccca tcagtacacc
     4621 acctaacccg ctacgtaatg ttgtttgtgc atcagcagcg cgaacgcgga actcacggct
     4681 cgctttggct gcaataaatg accccacgaa gatccctaac accaggaaaa cgccccagtt
     4741 aatgtatttc acgtcacccg cgaccagaaa ttgcagaata ttggccgttg gggaagtgat
     4801 tcctaaccca aacatgcgtc cggttgcttc actcaggggc caggctaaaa gcgcaatcaa
     4861 accgatgagt acagcagtga caaagggatg ccagcgtttt tcaaacagaa tatgagcgat
     4921 cccggttcgg cgcggcggta aggtcgcgac tttgagtttt ggcttcttca actctttcat
     4981 caccacccag agcgttatca ccagcaaaac ggtaaccaac ggccacacag acaaattaaa
     5041 agtctcagca atagagttat gttcagtact gtagtgctgc aaggtttgat ttaaaccact
     5101 ggcgtgtgga gaacgcatca ccgcactcat caccatataa gtgaaaagcg cgatccaact
     5161 gccgatcaat ccctcacccg cgcgatacca ggtcccggtg gcacatccac ccgccagaac
     5221 aattcccagc ccgaaaagat acccacctat aacagtacca agccacggga acgccccggc
     5281 ttcgtaagtc agtaggcccg cctgaattaa cgcaaaaacc cccacgcttt gtaccgaaat
     5341 tgcaatcagc aaggcgtaaa acatgcgatt atttttcgcg atatacatat cgcgaaaacc
     5401 acctgtcagg caaaaacgcc cacgctgcat gacaaatccc agcagagcac cacaaattag
     5461 cccgcttaat atcattgaaa acataaatta attaaccaga tgaatgttaa tggggaaatt
     5521 attcatgact ggtggaatgc agaccaataa ccaaattctc taaattagaa caaatggtta
     5581 ttaatgagga tgtcgataaa aaagaataaa aaaaccggag ccaaatattc attcgactcc
     5641 ggtttattat tagaaaagat gattatgcta cgtcttcgta ctgcggaacc gggttacgga
     5701 agctcttggt gacgcaagcc aggtaaatca gaccgatagc agcccagatc agacccagaa
     5761 ccattgagct ttcttccagg ttaacccaca gcgcaccaac ggtcagcgca ccacacatcg
     5821 gcaggaacag atactggaag tgatctttca gcgtcttgtt acgcttctca cggatccaga
     5881 actgcgaaat aaccgacagg ttaacgaagg tgaacgccac cagcgcacca aagttaatca
     5941 gcgccgtagc cattaccagg tcgaagttga ttgccagcag agcaatcgcg ccaaccagga
     6001 tgatgttcat cgccggagta cgccatttcg ggtgtacata accgaagaag cttttcggga
     6061 acacgccgtc acgacccatt acgtacatca gacgcgctac gcctgcgtgc gccgccatac
     6121 cggacgccag tacggtaatg gtggagaaga tcagcgcgcc aacctggaac gctttacccg
     6181 caacgtacag catgatttca ggctgtgacg catccggatc tttaaagcga gagatatccg
     6241 ggaagtacag ctgcaggaag taagttgcaa agatgaagat catgccgcca atcagcgcgg
     6301 tcaggaaaat tgcgcgcggg atcacgcgct ctgcatcttt ggtttcttcc gacaggttac
     6361 taatgccgtc aaagccggta aaggagaagc acaagattgt cgccccggta atcatcggga
     6421 taacatgcgc atcgccagac cagaacggac gagtgctcgc cagcgtaccc gcgccttcac
     6481 cttcaaatac gccataaaca accatgccca ggatcaccgc gatcagcact acctgcaaca
     6541 cgacgattac agtgttgaag ttcgctacgg atttcagact acgcaggtta aaggcggtca
     6601 taaaggccac cagcgccacc acaaacatcc acgatgggat ggaaggcacc agagcttcaa
     6661 aatagatttt cgccagcaga atgttgatca tcggcgcgaa cagatagtcg agcagagaag
     6721 accaacccac cataaagccg acagtcgggc taatggattt ctgggcgtaa gtgtatgcag
     6781 agccagcaga aggatagcgg cgaaccagct tcccgtagct cagagccgta aacaggatcg
     6841 caatcaatgc gaacgcatag gctgtcggca catgaccatc cgtgaggcct gaaacgatac
     6901 caaatgtatc aaacagcgtc atcggctgca tataggcaag acccatcatt acaaccggaa
     6961 ctaacgtaag cgttttacgc aattccacgc gagaggtgtt tggagtaacg ttatgcgaca
     7021 tggtcattct cctttacggt gataaccgtc gcgtaagcaa aaaattgccc catttttttg
     7081 gattcctcag cgacaacaac tgtcgatttt tagtaaatat ctatccggta cgaagcccgg
     7141 cctcttggta tgaatgattg gtttgaagca aaaaataacc gacgctgatg aaacgtcggt
     7201 ttttagtcat tttttgacag cggcgcattg tgcctaaatg ggggggaaat gacaagagaa
     7261 tgagaggctt gtcataataa tttttcttta aatggctgat tttccgtcat cagattttgc
     7321 ataaacaccg gcgatcgcac tatttgctaa aatttcatcc cgccaccagc cactggcaag
     7381 tcctgcggtc tgttcgttcc agccaatcca gacgggttca aagagagttt gggcgaccac
     7441 tttcttctcg attaacgcgc cactatcgag aaaacgttgc gccagataac ggggtaaata
     7501 gccgcagccg aggccgctaa tttgcagctc cagcttggtt ttaaaatcga aaacggtaat
     7561 ggcttcttgt tcgtcgagaa gttgtgaggc cgtagaagcg ccggcctgcg cagtgtcccc
     7621 caccacaatc gcccgatatc gcttaatgat acgacggttt aacggttctt cttccagggc
     7681 taacggatga tgaggcgcga ccgcaaagac ttgttccaga tcgcccaacc gtgaaaaacc
     7741 aaactcactg gaagatggtg gctcatgcat cgcgccaaca ataatatccg ctcgcccctg
     7801 agtcagggca tcccaggaac caccgagtac gccattgata aacttcaggc gcgtcacgct
     7861 atgatgttga taaaaagctt caatcagtgg cgcaagcaga gaaaaaggaa acgtgtcgtc
     7921 cacgccaatc accagctcgt tttcccagcc ttcatgcagt ttgatcgcct gcttttccag
     7981 ttcccgcacg gtatgcagaa cttcccgccc tttctctaat aacatttttc cggtgcgggt
     8041 gaatttagcg cggtgaccgc tacgatcaag caattgaata ttaaggtcgc tttccagctt
     8101 gtgaacggtg taactcagag cggacggcgt cttgtagagt ttggccgacg ccgccgcaaa
     8161 actgccttct ttttctaagg catcgaggat catcaacaca tccagcagtg gtttcataca
     8221 cgcccccttg cagtgtatgc ggcgtcctgc tggcgtgatc gtttactcca gcggcattac
     8281 cagcggatcg ggatactggt attcaaatcc cagttcatta caaatccgac tgccatcaat
     8341 aatcttacct ttgccgctgt ccagactatt tctgaactgc ggaggttcca gccccagtaa
     8401 acgggccatc tgcggataga aaacattacg cgcagggtga gctggcgcac atatattata
     8461 gatgtgtccg cctttaggtg cctgtaacaa cagagtgata gcgccaataa catcttctaa
     8521 atggactaaa ttaacaccat gttcaccatc aggcgcggtt tttccggcaa agaagcgtcc
     8581 gggatgacgc cccggtccga ccaggcccgc aagacgcaga atatcgaccg aagtaccggg
     8641 taaattgtgc agccagtctt cgagttcttc taatactcgt ccactgttgg ttaccggatt
     8701 acgcggggta gtttctttca ccatgccttg cgcatcgcca tagacagatg ttgagctggt
     8761 aaaaataatt cggggaatac gatgggccag cgcgctatcc actaactctt gtaccgcttg
     8821 taaatagaac tcatcgccgg agccgctacg acgtgccgga agcgtaatga ccagtgcatc
     8881 ggcatccatc agggcatcca gatcgtcaga atcgcaaact aactcaggct ccatgcgaag
     8941 cagatagcta tcaatgccac tcattcgggc tgcttcgaca ccatcttgtg tggttttact
     9001 cccggtgact tgccagcctc gcgctgaaag tgacatcgcc agcggcatgc ctaaccaccc
     9061 taacccgaca attgcgacct ttttcatccg ttatctcctg atacacctta gatctataag
     9121 gctacgctag cgtatcaaaa ctgacaattc attctatgaa tgaatctgtt caataatgat
     9181 aacgacatgc tgcaatgagc agtgaatcgt cggtaaccgc gtataccaga cggtgctcct
     9241 ctgtaatgcg tcgggaccag aaacctgaca aattatgttt caggggttct ggcttcccct
     9301 taccttcaaa tggcgttctg cgggtatctt tgataagttc attgatcttt ttaacaattc
     9361 gcttatctgt ttcctgccag tacagataat catcccatga ttcctcagac cagattagtt
     9421 tcactcaata atgtcctttt ccgttccttt gcctgatttc aggctatcga ttgagtccat
     9481 caatctccgg gcgttagcgg gggaacgcag tagataagcc gtctcttcca gcgagttgta
     9541 ttcttcgagt gacatcagaa cacaagcctc tccattctga cgagtaatga ggatcggggc
     9601 atgatcttca acggctttca tcattgttgc cgacaaattc tgacgcgctt cgctgtaact
     9661 aattgtacgc atgtcaatct cctcttttgt acagttcatt gtacaatgat agacgttaat
     9721 taactattta ttaattagtt tgtagatcaa gacattgtca gtgagacgaa aaatccaggc
     9781 ttcgctattt ttggtaccgt cagcttagag gtcagtcctc ttagccccct cctttccccg
     9841 ctcattcatt aaacaaatcc atcgccataa aatatataaa aaagcccttg ctttctaacg
     9901 tgaaagtggt ttaggttaaa agacatcagt tgaataaaca ttcacagaga cttttatgac
     9961 tcgcgttcaa tttaaacacc accatcatca ccatcatcct gactagtctt tcaggcgatg
    10021 tgtgctggaa gacattcaga tcttccagtg gtacatgaac gcatgagaaa gcccccggaa
    10081 gatcaccttc cgggggcttt tttattgcgc ggttgataac ggttcagaca gatttaaaga
    10141 ggaataacaa aatgacagac aacactcgtt tacgcatagc tatgcagaaa tccggccgtt
    10201 taagtgatga ctcacgtgaa ttgctggcgc gctgtggcat taaaatcaat cttcacaccc
    10261 agcgcctgat cgcgatggca gaaaacatgc cgattgatat tctgcgcgtg cgtgacgacg
    10321 acattcccgg tctggtgatg gacggcgtgg tagaccttgg gattatcggc gaaaacgtgc
    10381 tggaagaaga actgcttaac cgccgcgccc agggtgagga tccacgctac tttaccctgc
    10441 gtcgtctgga tttcggcggc tgtcgccttt cgctggcaac gccggttgat gaagcctggg
    10501 acggtccgct ctccttaaac ggtaaacgta tcgccacctc ttatcctcac ctgctcaagc
    10561 gttatctcga caagaaaggt atctctttta aatcctgctt actgaacggt tctgttgaag
    10621 ttgcgccgcg tgccggactg gcggatgcga tttgcgattt ggtttccacc ggtgccacgc
    10681 tggaagctaa cggcctgcgc gaagtcgaag ttatctaccg ctcgaaagcc tgccttatcc
    10741 agcgcgatgg tgaaatggaa gaatccaaac agcagctgat cgacaaactg cttacccgta
    10801 ttcagggtgt gatccaggcg cgcgaatcaa aatacatcat gatgcacgca ccgaccgaac
    10861 gcctggatga agtcatcgcc ctgctgccag gtgccgaacg cccaactatt ctaccgctgg
    10921 cgggtgatca acaacgcgta gcgatgcaca tggtcagtag cgaaaccctg ttctgggaaa
    10981 cgatggaaaa actgaaagcg ctgggtgcca gttcaatcct ggtcctgccg attgagaaga
    11041 tgatggagtg atcgccatga gctttaacac aatcattgac tggaatagct gtactgcgga
    11101 gcaacaacgc cagctgttaa tgcgcccggc gatctccgct tctgaaagca ttacccgcac
    11161 tgttaacgat attctcgata acgtgaaagc acgcggcgat gaggccctgc gggaatacag
    11221 cgcgaagttt gataaaacca cggttaccgc gctgaaggtg tctgctgagg aaattgccgc
    11281 cgccagcgaa cgcctgagcg acgagctaaa acaggcgatg gcggtggcag taaagaatat
    11341 tgaaaccttc cacactgcgc aaaaactgcc gccggtagat gtagaaacgc agccaggcgt
    11401 acgttgccag caagtcacgc gcccggtaga ttcagtgggt ttgtatattc ctggcggctc
    11461 cgccccgctc ttctcaacgg tattaatgct ggcaactccg gcgcgtattg cgaactgtaa
    11521 aaaagtggtg ctgtgctcac cgccgccgat tgccgatgag atcctttacg cggcgcagct
    11581 gtgcggtgta caggacgtgt ttaacgtcgg cggcgcacag gccattgccg cgctggcgtt
    11641 tggtacggaa tctgtgccga aagtggacaa aatcttcggg ccgggtaacg cctttgtcac
    11701 cgaggcaaaa cgtcaggtga gccagcgtct ggacggtgcg gcgatcgata tgcccgcagg
    11761 cccttcggaa gtgctggtga ttgctgacag cggcgcaacg ccggatttcg tggcttctga
    11821 tttgctttcc caggctgaac acggcccgga ctcacaggtg attttactga cgcccgctgc
    11881 tgatatggcg cgtcgcgtag ccgaagctgt cgaacgcctg ctggcagaac tgccgcgagc
    11941 tgaaaccgcc cgccaggcac tgaacgccag ccgcctgatc gtgactaaag atttagcgca
    12001 gtgcgtagag atctccaacc agtacggccc ggagcacctg atcattcaga cccgcaacgc
    12061 ccgcgatctg gtcgatggca tcaccagcgc cggttcggta tttcttggtg actggtcacc
    12121 ggaatccgca ggtgattacg cctccggcac caaccacgtt ctgccgactt acggttacac
    12181 cgccacctgt tccagcctcg ggctggcaga tttccagaag cgtatgaccg tgcaggaact
    12241 gtcgaaagaa ggcttctccg cgctggcttc aaccattgaa acactggccg ccgccgagcg
    12301 cctgaccgcc cataaaaatg ccgttacttt gcgtgttaac gcccttaagg agcaagcatg
    12361 agcaccgtga ctatcaccga tttagcgcgt gaaaacgtcc gcaacctgac gccgtatcag
    12421 tcggcgcgtc gtctgggcgg taacggcgac gtctggctga acgccaacga ataccccaca
    12481 gccgtggagt ttcagcttac tcagcaaacg ctcaaccgct acccggaatg tcagccgaaa
    12541 gcggtgattg aaaattacgc gcagtatgca ggcgtaaaac cggagcaggt gctggtcagc
    12601 cgtggcgcgg acgaaggtat tgaactactg attcgcgctt tttgcgaacc aggtaaagac
    12661 gccatcctct actgcccgcc aacgtacggc atgtacagcg tcagcgctga aaccattggc
    12721 gtcgagtgcc gcacagtgcc gacgctggac aactggcaac tggacttaca gggcatttcc
    12781 gacaagctgg acggcgtaaa agtggtctat gtttgcagcc ccaacaaccc gaccgggcaa
    12841 ctgatcaacc cgcaggattt tcgcactctg ctggagttaa cccgcggtaa agcgattgtg
    12901 gttgccgatg aagcctatat cgagttttgc ccgcaggcat cgttggctgg ctggctggcg
    12961 gaatatccgc acctggctat tttgcgcaca ctgtcgaaag cttttgctct ggcgggcctt
    13021 cgttgcggat ttacgctggc aaacgaagaa gtcatcaacc tgctgatgaa agtgatcgcc
    13081 ccctacccgc tctcgacgcc ggttgccgac attgcggccc aggcgttaag cccgcagggg
    13141 atcgtcgcca tgcgcgaacg ggtggcgcaa attattgcag agcgcgaata cctgattgcc
    13201 gcactgaaaa aaatctcctg cgtggagcag gtttttgact ctgaaaccaa ctacattctg
    13261 gcgcgcttta aagcctccag cgcagtgttt aaatctttgt gggatcaggg cattatctta
    13321 cgtgatcaga ataaacaacc ctctttaagc ggctgcctgc gaattaccgt cggaacccgt
    13381 gaagaaagcc agcgcgtcat tgacgcctta cgtgcggagc aagtttaatg agtcagaagt
    13441 atctttttat cgatcgcgat ggaaccctga ttagcgaacc gccgagtgat tttcaggtgg
    13501 accgttttga caaactcgcc tttgaaccgg gcgtgatccc ggagctgctg aagctgcaaa
    13561 aagcgggcta caagctggtg atgatcacta atcaggatgg tctgggaaca caaagtttcc
    13621 cgcaggcgga ttttgatggc ccgcacaacc tgatgatgca gatcttcacc tcgcaaggcg
    13681 tgcagtttga tgaagtgctg atttgtccgc acctgcccgc cgatgagtgc gactgccgta
    13741 agccgaaagt aaaactggtg gagcgttatc tcgctgagca agcgatggat cgtgccaata
    13801 gttatgtgat tggcgatcgc gcgaccgata ttcagctggc ggaaaacatg ggcattaatg
    13861 gtttacgcta cgaccgtgaa accctgaact ggccgatgat tggcgagcaa ctcactaaac
    13921 gagaccgttc cgcccatgta gtgcgcaaca ccaaagagac gcagattgac gttcaggtgt
    13981 ggctggatcg cgaaggtggc agcaagatta acaccggcgt tggcttcttt gatcatatgc
    14041 tggatcagat cgccactcac ggcggtttcc gcatggaaat caacgtcaaa ggcgacctct
    14101 atatcgacga tcaccacacc gtcgaagata ccggcctggc gctgggcgaa gcgttaaaaa
    14161 ttgccctcgg cgataaacgc ggtatttgtc gctttggttt tgtgctaccg atggacgaat
    14221 gccttgcccg ctgcgcgctg gatatctctg gtcgcccgca cctggaatat aaagccgagt
    14281 ttacctacca gcgcgtgggc gatctcagca ccgagatgat cgagcacttc ttccgttcgc
    14341 tctcttacac catgggcgtg acgctccacc tgaaaaccaa aggtaaaaac gatcaccacc
    14401 gtgtagagag cctgttcaaa gcctttggtc gcaccctgcg ccaggccatc cgcgtggaag
    14461 gcgacaccct gccctcgtcg aaaggagtgc tgtaatgaac gtggtgatcc ttgataccgg
    14521 ctgcgccaat ttgaactcgg tgaagtcagc cattgcgcgt cacggttatg aacccaaagt
    14581 cagccgtgac ccggacgtcg tgttgctggc cgataaacta tttttacccg gcgttggcac
    14641 cgcacaagca gcgatggatc aggtccgtga gcgcgagctg tttgatctca tcaaagcctg
    14701 tacccaaccg gtgctgggca tctgcttagg gatgcaactg ctggggcggc gcagtgaaga
    14761 gagcaacggc gtcgatctgc tgggcatcat cgacgaagac gtgccgaaaa tgaccgactt
    14821 tggtctgccg ctgccgcata tgggctggaa ccgcgtttac ccgcaggcag gcaaccgcct
    14881 gtttcagggg attgaagacg gcgcgtactt ttactttgtt cacagctacg caatgccagt
    14941 caatccgtgg accatcgccc agtgtaacta cggcgaaccg ttcaccgcgg cggtacaaaa
    15001 agataacttc tacggcgtgc agttccaccc ggagcgttct ggtgctgctg gcgctaattt
    15061 gctgaaaaac ttcctggaga tgtgatgatt attccggcat tagatttaat cgacggcacc
    15121 gtggtgcgtc tccatcaggg cgattacggc aaacagcgcg attacggtaa cgacccgctg
    15181 ccacgcttac aggattacgc cgcgcagggt gccgaagtgt tgcatctggt ggatctgacc
    15241 ggggcaaaag atccggctaa acgtcaaatc ccgctgatta aaaccctggt cgcgggcgtt
    15301 aacgttccgg tgcaggttgg cggcggcgtg cgtagcgaag aagacgtggc ggcgttactg
    15361 gaagcgggcg ttgcgcgcgt ggtggttggc tccaccgcgg tgaaatcacc agaaatggtg
    15421 aaaggctggt ttgaacgctt cggtgccgat gccttagtgc tggcgctgga tgtccgtatt
    15481 gacgagcaag gcaacaagca ggtggcagtc agcggctggc aagagaactc gggcgtttca
    15541 ctggaacaac tggtggaaac ctatctgccc gtcggcctga aacatgtgct gtgtaccgat
    15601 atctcgcgcg acggcacgct ggcaggttct aacgtctctt tatatgaaga agtgtgcgcc
    15661 agatatccgc aggtggcatt tcagtcttcc ggcggtattg gcgacattga tgatgtcgcg
    15721 gccctgcgtg gtactggcgt gcgcggcgta atagttggtc gtgcattact ggaaggtaaa
    15781 ttcaccgtga aggaggccat cgcatgctgg caaaacgcat aatcccatgt ctcgacgttc
    15841 gtgatggtca ggtggtgaaa ggcgtacagt ttcgcaacca tgaaatcatt ggcgatattg
    15901 taccgctggc aaaacgctac gctgaagaag gtgcagacga actggtgttc tacgatatca
    15961 ccgcttccag cgatggccgt gtggtagata aaagctgggt atctcgcgtg gcggaagtga
    16021 tcgacattcc gttctgtgtg gcgggtggga ttaagtctct ggaagatgcc gcgaaaattc
    16081 tttcctttgg cgcggataaa atttccatca actctcctgc gctggcggac ccgacgttaa
    16141 ttactcgcct ggcggatcgc tttggcgtgc agtgtattgt ggtcggtatt gatacctggt
    16201 acgacgctga aaccggtaaa tatcatgtga atcaatatac cggcgatgaa agccgcaccc
    16261 gcgtcactca gtgggaaacg ctcgactggg tagaggaagt gcaaaaacgc ggtgccggag
    16321 aaatcgtcct caacatgatg aatcaggacg gcgtgcgtaa cggttacgac ctagaacaac
    16381 tgaaaaaagt gcgtgaagtt tgccacgtcc cgctgattgc ctccggtggc gcgggcacca
    16441 tggaacactt cctcgaagcc ttccgcgatg ccgacgttga cggtgcgctg gcagcttctg
    16501 tattccacaa acaaataatc aatattagtg aattaaaagc gtacctggca acacagggcg
    16561 tggagatcag gatatgttaa cagaacaaca acgtcacgaa ctggactggg aaaaaaccga
    16621 cggactgatg ccggtgattg tacaacacgc ggtatctggc gaagtgttaa tgctgggcta
    16681 tatgaacccg gaagctctgg acaaaactat cgaaagcggc aaagtcacct tcttctcgcg
    16741 aactaaacaa cggctgtgga ccaaaggcga aacgtctggc aattttctca atgtggtgag
    16801 tattgccccg gactgcgaca acgacacgtt actggtgctg gcgaatccca tcgggccaac
    16861 ctgccacaaa ggcaccagca gctgcttcgg cgacaccgct caccagtggc tgttcctgta
    16921 tcaactggaa caactgctcg ccgaacgcaa atctgccgac ccggaaacct cttacacagc
    16981 caaactgtat gccagcggca ccaaacgcat tgcgcagaaa gtgggcgaag aaggggtgga
    17041 aaccgcactg gccgcgacgg taaatgaccg ctttgagctg accaacgagg catctgattt
    17101 gatgtatcac ctgctggtgc tgttgcagga tcaggggctg gatctcggag aagtgattga
    17161 taatctgaag aatcggcatt aacgcgttgg cccccgcagc aacggcgggg gtagcagctc
    17221 tcaggatttg ctttccagca atgtagtgta gagattgaca taggcgtcaa tcatatggtc
    17281 ggcagtaaac atctcttcaa aacgacgacg cgagttttcg ccatagcggt tggaggtttc
    17341 ctcgttattc cagagctcat tcatcgcctc caccagcgcc tggctatcat tcggcggaat
    17401 cacgcaacca ctcactttgt cctggttaat gaaagaggta cctgtaccga tctcgcaaga
    17461 gatcagaggc cttgcaaagc gtgcgccttc caataacgta atgccaaacg cctcagagcg
    17521 cagatgcgag gggaatacca cgccccggca gagctggaag agaatgtact tatcttcgtc
    17581 gttgagcatg ccggtaaaca ccacattgct cagcccgcgt tgctgcgcct cacgccgcac
    17641 ttccgcctcc agcggcccgc ccccgacgat caccaccggc agccggctac gctcggcggc
    17701 atccagcaga atgtgcagcc ctttgtagta gcggaaagcg ccgacgaaga ggaagaagtt
    17761 atcgccgacg gtttcccgcc agtgcgccac ccgctgcgga tcgtgctgca cgtcatgctg
    17821 ctccagacca aacgggatca ccacggtttt atcctgatat tttttcaggg tctggctgga
    17881 ggccacgtag ttgggcgacg aggcgacgat gcagtctacg ctggcgagga atcgctcctg
    17941 cagcggctgg tacaacttca ttaaccgttt ttgtttcaca atatccgagt gataggtcac
    18001 caccgttctt gcgtcaggcc gcgccgagag atgcaacata tccatgaaag gaaacggaaa
    18061 atggtagttg atgatgtcgt aatcatcttt aatctgctta aaacgcttta acgctttcaa
    18121 cgaaaacggc gtggaggcaa tttcaaaaag ctgcttatta taaatgaccc gatggt
//
LOCUS       DAPOAV010000086        17903 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.086, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000086 DAPOAV010000000
VERSION     DAPOAV010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17903
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.086"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(162..1445)
                     /gene="gltA"
                     /locus_tag="RN951_003465"
     CDS             complement(162..1445)
                     /gene="gltA"
                     /locus_tag="RN951_003465"
                     /EC_number="2.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (Si)-synthase"
                     /protein_id="HDX2528415.1"
                     /translation="MADTKAKLTLNGDTAVELDVLKGTLGQDVIDIRTLGSKGVFTFD
                     PGFTSTASCESKITFIDGDEGILLHRGFPIDQLATDSNYLEVCYILLNGEKPTQEQYD
                     EFKTTVTRHTMIHEQITRLFHAFRRDSHPMAVMCGITGALAAFYHDSLDVNNPRHREI
                     AAFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAGNFLNMMFSTPCEPYEVNPILER
                     AMDRILILHADHEQNASTSTVRTAGSSGANPFACIAAGIASLWGPAHGGANEAALKML
                     EEISSVKHIPEFVRRAKDKNDSFRLMGFGHRVYKNYDPRATVMRETCHEVLKELGTKD
                     DLLEVAMELENIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAMARTVGW
                     IAHWSEMHSDGMKIARPRQLYTGYEKRDFKSDIKR"
     gene            complement(1651..1758)
                     /locus_tag="RN951_003466"
     CDS             complement(1651..1758)
                     /locus_tag="RN951_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528416.1"
                     /translation="MRKSYEVGISPKINLCNSVEVLTNSFGTVISGRQV"
     gene            2139..2543
                     /gene="sdhC"
                     /locus_tag="RN951_003467"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
     CDS             2139..2543
                     /gene="sdhC"
                     /locus_tag="RN951_003467"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HDX2528417.1"
                     /translation="MWALFMIRNVKKQRPVNLDLQTIRFPITAIASILHRVSGVITFV
                     AVGILLWLLGTSLSSPEGFEQASAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFG
                     YLEETFEAGKRSAKISFVITVVLSLLAGVLVW"
     gene            2537..2884
                     /gene="sdhD"
                     /locus_tag="RN951_003468"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
     CDS             2537..2884
                     /gene="sdhD"
                     /locus_tag="RN951_003468"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase membrane anchor subunit"
                     /protein_id="HDX2528418.1"
                     /translation="MVSNASALGRNGVHDFILVRATAIVLTLYIIYMVGFFATSGELT
                     YEVWIGFFASAFTKVFTLLALFSILIHAWIGMWQVLTDYVKPLALRLMLQLVIVVALV
                     VYVIYGFVVVWGV"
     gene            2884..4650
                     /gene="sdhA"
                     /locus_tag="RN951_003469"
     CDS             2884..4650
                     /gene="sdhA"
                     /locus_tag="RN951_003469"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase flavoprotein subunit"
                     /protein_id="HDX2528419.1"
                     /translation="MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRS
                     HTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHM
                     GLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTI
                     FSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHIN
                     TGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERY
                     APNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELS
                     RTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACV
                     SVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNN
                     RNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNT
                     QRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYLPESESM
                     TRRSVNMEPKLRPAFPPKIRTY"
     gene            4666..5382
                     /gene="sdhB"
                     /locus_tag="RN951_003470"
     CDS             4666..5382
                     /gene="sdhB"
                     /locus_tag="RN951_003470"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase iron-sulfur subunit
                     SdhB"
                     /protein_id="HDX2528420.1"
                     /translation="MRLEFSIYRYNPDVDDAPRMQDYTLEADEGRDMMLLDALIQLKE
                     KDPSLSFRRSCREGVCGSDGLNMNGKNGLACITPISALNQPGKKIVIRPLPGLPVIRD
                     LVVDMGQFYAQYEKIKPYLLNNGQNPPAREHLQMPEQREKLDGLYECILCACCSTSCP
                     SFWWNPDKFIGPAGLLAAYRFLIDSRDTETDSRLDGLSDAFSVFRCHSIMNCVSVCPK
                     GLNPTRAIGHIKSMLLQRNA"
     gene            5683..8484
                     /gene="sucA"
                     /locus_tag="RN951_003471"
     CDS             5683..8484
                     /gene="sucA"
                     /locus_tag="RN951_003471"
                     /EC_number="1.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="HDX2528421.1"
                     /translation="MQNSALKAWLDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRST
                     FQQLPGTGVKPDQFHSQTREYFRRLAKDASRYSSTISDPDTNVKQVKVLQLINAYRFR
                     GHQHANLDPLGLWQQDKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEAL
                     KQTYCGPIGAEYMHITSTEEKRWIQQRIESGRATFNSEEKKRFLSELTAAEGLERYLG
                     AKFPGAKRFSLEGGDALIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQ
                     DLFDEFAGKHKEHLGTGDVKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSV
                     RARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQV
                     GFTTSNPLDARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFI
                     DLVCYRRHGHNEADEPSATQPLMYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNL
                     YRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRISTVPE
                     AVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFF
                     HRHAVIHNQSNGSTYTPLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIW
                     EAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQL
                     CAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGT
                     FLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAM
                     QEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLRYAGRPASASPAVGY
                     MSVHQKQQQDLVNDALNVE"
     gene            8499..9716
                     /gene="odhB"
                     /locus_tag="RN951_003472"
     CDS             8499..9716
                     /gene="odhB"
                     /locus_tag="RN951_003472"
                     /EC_number="2.3.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="HDX2528422.1"
                     /translation="MSSVDILVPDLPESVADATVATWHKKPGDAVVRDEVLVEIETDK
                     VVLEVPASADGILDAVLEDEGTTVTSRQILGRLREGNSAGKETSAKSEEKASTPAQRQ
                     QASLEEQNNDALSPAIRRLLAEHNLDASAIKGTGVGGRLTREDVEKHLAKAPAKESAP
                     AAAAPAAQPALAARSEKRVPMTRLRKRVAERLLEAKNSTAMLTTFNEVNMKPIMDLRK
                     QYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTP
                     RGLVTPVLRDVDTLGMADIEKKIKELAVKGRDGKLTVEDLTGGNFTITNGGVFGSLMS
                     TPIINPPQSAILGMHAIKDRPMAVNGQVEILPMMYLALSYDHRLIDGRESVGFLVTIK
                     ELLEDPTRLLLDV"
     gene            10082..11248
                     /gene="sucC"
                     /locus_tag="RN951_003473"
     CDS             10082..11248
                     /gene="sucC"
                     /locus_tag="RN951_003473"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="HDX2528423.1"
                     /translation="MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWV
                     VKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAAT
                     DIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQG
                     RELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGA
                     DGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIV
                     KLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFGGIVRCDLIADGIIG
                     AVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK"
     gene            11248..12117
                     /gene="sucD"
                     /locus_tag="RN951_003474"
     CDS             11248..12117
                     /gene="sucD"
                     /locus_tag="RN951_003474"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HDX2528424.1"
                     /translation="MSILIDKNTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKG
                     GTTHLGLPVFNTVREAVAATGATASVIYVPAPFCKDSILEAIDAGIKLIITITEGIPT
                     LDMLTVKVKLDEAGVHMIGPNCPGVITPGECKIGIQPGHIHKPGKVGIVSRSGTLTYE
                     AVKQTTDYGFGQSTCVGIGGDPIPGSNFIDILEMFEKDPQTEAIVMIGEIGGSAEEEA
                     AAYIKEHVTKPVVGYIAGVTAPKGKRMGHAGAIIAGGKGTADEKFAALEAAGVKTVRS
                     LADIGEALKTVLK"
     gene            complement(12221..12943)
                     /gene="mngR"
                     /locus_tag="RN951_003475"
     CDS             complement(12221..12943)
                     /gene="mngR"
                     /locus_tag="RN951_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-D-glycerate transport/metabolism system
                     transcriptional repressor MngR"
                     /protein_id="HDX2528425.1"
                     /translation="MGHKPLYRQIADRIREQIARGELKPGDALPTESALQTEFGVSRV
                     TVRQALRQLVEQQILESIQGSGTYVKEERVNYDIFQLTSFDEKLSDRHVDTHSEVLIF
                     EVIPADDFLQQQLQITPQDRVWHVKRVRYRKQKPMALEETWMPLALFPDLTWQVMENS
                     KYHFIEEVKKMVIDRSEQEIIPLMPTEEMSRLLNISQTKPILEKVSRGYLVDGRVFEY
                     SRNAFNTDDYKFTLIAQRKSSR"
     gene            13112..15028
                     /gene="mngA"
                     /locus_tag="RN951_003476"
     CDS             13112..15028
                     /gene="mngA"
                     /locus_tag="RN951_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001393949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HDX2528426.1"
                     /translation="MNLTTLTHRDALCLNARFTSREEAIHALTQRLAALGKISSTEQF
                     LEEVYRRESLGPTALGEGLAVPHGKTAAVKEAAFAVATLSEPLQWEGVDGPEAVDLVV
                     LLAIPPNEAGTTHMQLLTALTTRLADDEIRARIQSATTPDELLSALDDKGGTQPSASF
                     SNAPTIVCVTACPAGIAHTYMAAEYLEKAGRKLGVNVYVEKQGANGIEGRLTADQLNS
                     ATACIIAAEVAIKESERFNGIPALSVPVAEPIRHAEALIQQALTLKRSDETRTVQQDT
                     QPVKSVKTELKQALLSGISFAVPLIVAGGTVLAVAVLLSQIFGLQDLFNEENSWLWMY
                     RKLGGGLLGILMVPVLAAYTAYSLADKPALAPGFAAGLAANMIGSGFLGAVVGGLIAG
                     YLMRWVKNHLRLSSKFNGFLTFYLYPVLGTLGAGSLMLFVVGEPVAWINNSLTAWLNG
                     LSGSNALLLGAILGFMCSFDLGGPVNKAAYAFCLGAMANGVYGPYAIFASVKMVSAFT
                     VTASTMLAPRLFKEFEIETGKSTWLLGLAGITEGAIPMAIEDPLRVIGSFVLGSMVTG
                     AIVGAMNIGLSTPGAGIFSLFLLHDNGAGGVMAAIGWFGAALVGAAISTAILLMWRRH
                     AVKHGNYLTDGVMP"
     gene            15046..17679
                     /gene="mngB"
                     /locus_tag="RN951_003477"
     CDS             15046..17679
                     /gene="mngB"
                     /locus_tag="RN951_003477"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HDX2528427.1"
                     /translation="MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQD
                     NEYKYYVLDGQTAILEDYFAVKPENKDRVKKQVEAGKLIIGPWYTQTDTTIVSAESIV
                     RNLMYGMRDCLAFGEPMKIGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDK
                     TEFLWQSSDGSEVTAQVLPLGYAIGKYLPADENGLRKRLDSYFDVLEKASVTKEILLP
                     NGHDQMPLQQNIFEVMDKLREIYPQRKFVMSRFEEVFEKIEAQRDNLATLKGEFIDGK
                     YMRVHRTIGSTRMDIKIAHARIENKIVNLLEPLATLAWTLGFEYHHGLLEKMWKEILK
                     NHAHDSIGCCCSDKVHREIVARFELAEDMADNLIRFYMRKIADNMPQSDADKLVLFNL
                     MPWPREEVINTTVRLRASQFNLRDDRGQPVPYFIRHAREIDPGLIDRQIVHYGNYDPF
                     MEFDIQINQIVPSMGYRTLYIEANQPGNVIAAKSDAEGILENAFWQIALNEDGSLQLV
                     DKDSGVRYDRVLQIEESSDDGDEYDYSPAKEEWVITAANAKPQCDIIHEAWQSRAVIR
                     YDMAVPLNLSERSARQSTGRVGVVLVVTLSHNSRRIDVDINLDNQADDHRLRVLVPTP
                     FNTDSVLADTQFGSLTRPVNDSAMNNWQQEGWKEAPVPVWNMLNYVALQEGRNGMAVF
                     SEGLREFEVIGEEKKTFAITLLRGVGLLGKEDLLLRPGRPSGIKMPVPDSQLRGLLSC
                     RLSLLSYTGTPTAAGVAQQARAWLTPVQCYNKIPWDVMKLNKAGFNVPESYSLLKMPP
                     VGCLISALKKAEDRQEVILRLFNPAESATCDATVAFSREVISCSETMMDEHITTEENQ
                     GSNLSGPFLPGQSRTFSYRLA"
BASE COUNT         4319 a         4479 c         4865 g         4240 t
ORIGIN      
        1 agtattgggt tgctgataat ttgagctgtt ctattctttt taaatatcta tataggtctg
       61 ttaatggatt ttatttttac aattttttgt gtttaggcat ataaaaatca acccgccata
      121 tgaacggcgg gttaaaatat ttacaactta gcaatcaacc attaacgctt gatatcgctt
      181 ttaaagtcgc gtttttcata tcctgtatac agctgacgcg gacgggcaat cttcataccg
      241 tcactgtgca tttcgctcca gtgggcgatc cagccaacgg tacgtgccat tgcgaaaatg
      301 acggtgaaca tggaagacgg aatacccatc gctttcagga tgataccaga gtagaaatcg
      361 acgttcgggt acagtttctt ctcgataaag tacgggtcgt tcagcgcgat gttttccagc
      421 tccatagcca cttccagcag gtcatccttc gtgcccagct ctttcagcac ttcatggcag
      481 gtttcacgca ttacggtggc gcgcgggtcg taatttttgt acacgcggtg accgaagccc
      541 attaggcgga aagaatcatt tttgtctttc gcacgacgaa caaattccgg aatgtgttta
      601 acggagctga tttcttccag cattttcagc gccgcttcgt tagcaccgcc gtgcgcaggt
      661 ccccacagtg aagcaatacc tgctgcgata caggcaaacg ggttcgcacc cgaagagcca
      721 gcggtacgca cggtggaggt agaggcgttc tgttcatggt cagcgtgcag gatcagaata
      781 cggtccatag cacgttccag aatcggatta acttcatacg gttcgcacgg cgtggagaac
      841 atcatattca ggaagttacc ggcgtaggag agatcgttgc gcgggtaaac aaatggctga
      901 ccaatggaat acttgtaaca catcgcggcc atggtcggca ttttcgacag caggcggaac
      961 gcggcaattt cacggtgacg aggattgtta acatccagcg agtcgtgata gaacgccgcc
     1021 agcgcgccgg taataccaca catgactgcc attggatgcg agtcgcgacg gaaagcatgg
     1081 aacagacggg taatctgctc gtggatcatg gtatgacggg tcaccgtagt tttaaattcg
     1141 tcatactgtt cctgagtcgg tttttcacca ttcagcagga tgtaacaaac ttccaggtag
     1201 ttagaatcgg tcgccagctg atcgatcggg aaaccgcggt gcagcaaaat accttcatca
     1261 ccatcaataa aagtaatttt agattcgcag gatgcggttg aagtgaagcc tgggtcaaag
     1321 gtgaacacac cttttgaacc gagagtacgg atatcaataa catcttgacc cagcgtgcct
     1381 ttcagcacat ccagttcaac agctgtatcc ccgttgaggg tgagttttgc ttttgtatca
     1441 gccatttaag gtctccttag cgccttattg cgtaagactg ccggaactta aatttgcctt
     1501 cgcacatcaa cctggcttta cccgtttttt atttggctcg ccgctctgtg aaagagggga
     1561 aaacctgggt acagagctct gggcgcttgc aggtaaagga tccattgatg acgaataaat
     1621 ggcgaatcaa gtacttagca atccgaatta ttaaacttgt ctaccactaa taactgtccc
     1681 gaatgaattg gtcaatactt ccacactgtt acataagtta atcttaggtg aaataccgac
     1741 ttcataactt ttacgcatta tatgcttttc ctggtaatgt ttgtaacaac tttgttgaat
     1801 gattgtcaaa ttagatgatt aaaaattaaa taaatgttgt tatcgtgacc tggatcactg
     1861 ttcaggataa aacccgacaa actatatgta ggttaattgt aatgattttg tgaacagcct
     1921 atactgccgc caggtctccg gaacaccctg caatcccgag ccacccagcg ttgtaacgtg
     1981 tcgttttcgc atctggaagc agtgttttgc atgacgcgca gttatagaaa ggacgctgtc
     2041 tgacccgcaa gcagaccgga ggaaggaaat cccgacgtct ccaggtaaca gaaagttaac
     2101 ctctgtgccc gtagtcccca gggaataata agaacagcat gtgggcgtta ttcatgataa
     2161 gaaatgtgaa aaaacaaaga cctgttaatc tggacctaca gaccatccgg ttccccatca
     2221 cggcgatagc gtccattctc catcgcgttt ccggtgtgat cacctttgtt gcagtgggca
     2281 tcctgctgtg gcttctgggt accagcctct cttcccctga aggtttcgag caagcttccg
     2341 cgattatggg cagcttcttc gtcaaattta tcatgtgggg catccttacc gctctggcgt
     2401 atcacgtcgt cgtaggtatt cgccacatga tgatggattt tggctatctg gaagaaacat
     2461 tcgaagcggg taaacgctcc gccaaaatct cctttgttat tactgtcgtg ctttcacttc
     2521 tcgcaggagt cctcgtatgg taagcaacgc ctccgcatta ggacgcaatg gcgtacatga
     2581 tttcatcctc gttcgcgcta ccgctatcgt cctgacgctc tacatcattt atatggtcgg
     2641 ttttttcgct accagtggcg agctgacata tgaagtctgg atcggtttct tcgcctctgc
     2701 gttcaccaaa gtgttcaccc tgctggcgct gttttctatc ttgatccatg cctggatcgg
     2761 catgtggcag gtgttgaccg actacgttaa accgctggct ttgcgcctga tgctgcaact
     2821 ggtgattgtc gttgcactgg tggtttacgt gatttatgga ttcgttgtgg tgtggggtgt
     2881 gtgatgaaat tgccagtcag agaatttgat gcagttgtga ttggtgccgg tggcgcaggt
     2941 atgcgcgcgg cgctgcaaat ttcccagagc ggccagacct gtgcgctgct ctctaaagtc
     3001 ttcccgaccc gttcccatac cgtttctgcg caaggcggca ttaccgttgc gctgggtaat
     3061 acccatgaag ataactggga atggcatatg tacgacaccg tgaaagggtc ggactatatc
     3121 ggtgaccagg acgcgattga atatatgtgt aaaaccgggc cggaagcgat tctggaactc
     3181 gaacacatgg gcctgccgtt ctcgcgtctc gatgatggtc gtatctatca acgtccgttt
     3241 ggcggtcagt cgaaaaactt cggcggcgag caggcggcac gcactgcggc agcagctgac
     3301 cgtaccggtc acgcactgtt gcacacgctt tatcagcaga acctgaaaaa ccacaccacc
     3361 attttctccg agtggtatgc gctggatctg gtgaaaaacc aggatggcgc ggtggtgggt
     3421 tgtaccgcac tgtgcatcga aaccggtgaa gtggtttatt tcaaagcccg cgctaccgtg
     3481 ctggcgactg gcggagcagg gcgtatttat cagtccacca ccaacgccca cattaacacc
     3541 ggcgacggtg tcggcatggc tatccgtgcc ggcgtaccgg tgcaggatat ggaaatgtgg
     3601 cagttccacc cgaccggcat tgccggtgcg ggcgtactgg tcaccgaagg ttgccgtggt
     3661 gaaggcggtt atctgctgaa caaacatggc gaacgtttta tggagcgtta tgcgccgaac
     3721 gccaaagacc tggcgggccg tgacgtggtt gcgcgttcca tcatgatcga aatccgtgaa
     3781 ggtcgcggct gtgatggtcc gtgggggcca cacgcgaaac tgaaactcga tcacctgggt
     3841 aaagaagttc tcgaatcccg tctgccgggt atcctggagc tttcccgtac cttcgctcac
     3901 gtcgatccgg tgaaagagcc gattccggtt atcccaacct gtcactacat gatgggcggt
     3961 attccgacca aagttaccgg tcaggcgctg actgtgaatg agaaaggcga agatgtggtt
     4021 gttccgggac tgtttgccgt tggtgaaatc gcttgtgtat cggtacacgg cgctaaccgt
     4081 ctgggcggca actcgctgct ggacctggtg gtctttggtc gcgcggcagg tctgcatctg
     4141 caagagtcta tcgccgagca gggcgcactg cgcgatgcca gcgagtctga tgttgaagcg
     4201 tctctggatc gcctgaaccg ctggaacaat aatcgtaacg gtgaagatcc ggtggcgatc
     4261 cgtaaagcgc tgcaagaatg tatgcagcat aacttctcgg tcttccgtga aggtgatgcg
     4321 atggcgaaag ggcttgagca gttgaaagtg atccgcgagc gtctgaaaaa tgcccgtctg
     4381 gatgacactt ccagcgagtt caacacccag cgcgttgagt gcctggaact ggataacctg
     4441 atggaaacgg cgtatgcaac ggctgtttct gccaacttcc gtaccgaaag ccgtggcgcg
     4501 catagccgct tcgacttccc ggatcgtgat gatgaaaact ggctgtgcca ctccctgtat
     4561 ctgccagagt cggaatccat gacgcgccga agcgtcaaca tggaaccgaa actgcgcccg
     4621 gcattcccgc cgaagattcg tacttactaa tgcggagaca ggaaaatgag actcgagttt
     4681 tcaatttatc gctataaccc ggatgttgat gatgctccgc gtatgcagga ttacaccctg
     4741 gaagcggatg aaggtcgcga catgatgctg ctggatgcgc ttatccagct aaaagagaaa
     4801 gatcccagcc tgtcgttccg ccgctcctgc cgtgaaggtg tgtgcggttc cgacggtctg
     4861 aacatgaacg gcaagaatgg tctggcctgt attaccccga tttcggcact caaccagccg
     4921 ggcaagaaga ttgtgattcg cccgctgcca ggtttaccgg tgatccgcga tttggtggta
     4981 gacatgggac aattctatgc gcaatatgag aaaattaagc cttacctgtt gaataatgga
     5041 caaaatccgc cagctcgcga gcatttacag atgccagagc agcgcgaaaa actcgacggg
     5101 ctgtatgaat gtattctctg cgcatgttgt tcaacctctt gtccgtcttt ctggtggaat
     5161 cccgataagt ttatcggccc ggcaggcttg ttagcggcat atcgtttcct gattgatagc
     5221 cgtgataccg agactgacag ccgcctcgac ggtttgagtg atgcattcag cgtattccgc
     5281 tgtcacagca tcatgaactg cgtcagtgta tgtccgaagg ggctgaaccc gacgcgcgcc
     5341 atcggccata tcaagtcgat gttgttgcaa cgtaatgcgt aaaccgtagg cctgataaga
     5401 cgcgcaagcg tcgcatcagg caaccagtgc cggatgcggc gtgaacgcct tatccggcct
     5461 acaagtcatt acccgtaggc ctgataagcg cagcgcatca ggcgtaacaa agaaatgcag
     5521 gaaatcttta aaaactgccc ctgacactaa gacagttttt aaaggttcct tcgcgagcca
     5581 ctacgtagac aagagctcgc aagtgaaccc cggcacgcac atcactgtgc gtggtagtat
     5641 ccacggcgaa gtaagcataa aaaagatgct taagggatca cgatgcagaa cagcgctttg
     5701 aaagcctggt tggactcttc ttacctctct ggcgcaaacc agagctggat agaacagctc
     5761 tatgaagact tcttaaccga tcctgactcg gttgacgcta actggcgttc gacgttccag
     5821 cagttacctg gtacgggagt caaaccggat caattccact ctcaaacgcg tgaatatttc
     5881 cgccgcctgg cgaaagacgc ttcacgttac tcttcaacga tctccgaccc tgacaccaat
     5941 gtgaagcagg ttaaagtcct gcagctcatt aacgcatacc gcttccgtgg tcaccagcat
     6001 gcgaatctcg atccgctggg actgtggcag caagataaag tggccgatct ggatccgtct
     6061 ttccacgatc tgaccgaagc agacttccag gagaccttca acgtcggttc atttgccagc
     6121 ggcaaagaaa ccatgaaact cggcgagctg ctggaagccc tcaagcaaac ctactgcggc
     6181 ccgattggtg ccgagtatat gcacattacc agcaccgaag aaaaacgctg gatccaacag
     6241 cgtatcgagt ctggtcgcgc gactttcaat agcgaagaga aaaaacgctt cttaagcgaa
     6301 ctgaccgccg ctgaaggtct tgaacgttac ctcggcgcaa aattccctgg cgcaaaacgc
     6361 ttctcgctgg aaggcggtga cgcgttaatc ccgatgctta aagagatgat ccgccacgct
     6421 ggcaacagcg gcacccgcga agtggttctc gggatggcgc accgtggtcg tctgaacgtg
     6481 ctggtgaacg tgctgggtaa aaaaccgcaa gacttgttcg acgagttcgc cggtaaacat
     6541 aaagaacacc tcggcacggg tgacgtgaaa taccacatgg gcttctcgtc tgacttccag
     6601 accgatggcg gcctggtgca cctggcgctg gcgtttaacc cgtctcacct tgagattgta
     6661 agcccggtag ttatcggttc tgttcgtgcc cgtctggaca gacttgatga gccgagcagc
     6721 aacaaagtgc tgccaatcac catccacggt gacgccgcag tgaccgggca gggcgtggtt
     6781 caggaaaccc tgaacatgtc gaaagcgcgt ggttatgaag ttggcggtac ggtacgtatc
     6841 gttatcaaca accaggttgg tttcaccacc tctaatccgc tggatgcccg ttctacgccg
     6901 tactgtactg atatcggtaa gatggttcag gccccgattt tccacgttaa cgcggacgat
     6961 ccggaagccg ttgcctttgt gacccgtctg gcgctcgatt tccgtaacac ctttaaacgt
     7021 gatgtcttca tcgacctggt gtgctaccgc cgtcacggcc acaacgaagc cgacgagccg
     7081 agcgcaaccc agccgctgat gtatcagaaa atcaaaaaac atccgacacc gcgcaaaatc
     7141 tacgctgaca agctggagca ggaaaaagtg gcgacgctgg aagatgccac cgagatggtt
     7201 aacctgtacc gcgatgcgct ggatgctggc gattgcgtag tggcagagtg gcgtccgatg
     7261 aacatgcact ctttcacctg gtcgccgtac ctcaaccacg aatgggacga agagtacccg
     7321 aacaaagttg agatgaagcg cctgcaggag ctggcgaaac gcatcagcac ggtgccggaa
     7381 gcagttgaaa tgcagtctcg cgttgccaag atttatggcg atcgccaggc gatggctgcc
     7441 ggtgagaaac tgttcgactg gggcggtgcg gaaaacctcg cttacgccac gctggttgat
     7501 gaaggcattc cggttcgcct gtcgggtgaa gactccggtc gcggtacctt cttccaccgc
     7561 cacgcggtga tccacaacca gtctaacggt tccacttaca cgccgctgca acatatccat
     7621 aacgggcagg gcgcgttccg tgtctgggac tccgtactgt ctgaagaagc agtgctggcg
     7681 tttgaatatg gttatgccac cgcagaacca cgcactctga ccatctggga agcgcagttc
     7741 ggtgacttcg ccaacggtgc gcaggtggtt atcgaccagt tcatctcctc tggcgaacag
     7801 aaatggggcc ggatgtgtgg tctggtgatg ttgctgccgc acggttacga agggcagggg
     7861 ccggagcact cctccgcgcg tctggaacgt tatctgcaac tttgtgctga gcaaaacatg
     7921 caggtttgcg taccgtctac cccggcacag gtttaccaca tgctgcgtcg tcaggcgctg
     7981 cgcgggatgc gtcgtccgct ggtcgtgatg tcgccgaaat ccctgctgcg tcatccgctg
     8041 gcggtttcca gcctcgaaga actggcgaac ggcaccttcc tgccagccat cggtgaaatc
     8101 gacgagcttg atccgaaggg cgtgaagcgc gtagtgatgt gttctggtaa ggtttattac
     8161 gacctgctgg aacagcgtcg taagaacaat caacacgatg tcgccattgt gcgtatcgag
     8221 caactctacc cgttcccgca taaagcgatg caggaagtgt tgcagcagtt tgctcacgtc
     8281 aaggattttg tctggtgcca ggaagagccg ctcaaccagg gcgcatggta ctgcagccag
     8341 catcatttcc gtgaagtgat tccgtttggg gcttctctgc gttatgcagg ccgcccggcc
     8401 tccgcctctc cggcggtagg gtatatgtcc gttcaccaga aacagcaaca agatctggtt
     8461 aatgacgcgc tgaacgtcga ataaataaag gatacacaat gagtagcgta gatattctgg
     8521 tccctgacct gcctgaatcc gtagccgatg ccaccgtcgc aacctggcat aaaaaacccg
     8581 gcgacgcagt cgtacgtgat gaagtgctgg tagaaatcga aactgacaaa gtggtactgg
     8641 aagtaccggc atcagcagac ggcattctgg atgcggttct ggaagatgaa ggtacaacgg
     8701 taacgtctcg tcagatcctt ggtcgcctgc gtgaaggcaa cagcgccggt aaagaaacca
     8761 gcgccaaatc tgaagagaaa gcgtccactc cggcgcaacg ccagcaggcg tctctggaag
     8821 agcaaaacaa cgatgcgtta agcccggcga tccgtcgcct gctggctgaa cacaatctcg
     8881 acgccagcgc cattaaaggc accggtgtgg gtggtcgtct gactcgtgaa gatgtggaaa
     8941 aacatctggc gaaagccccg gcgaaagagt ctgctccggc agcggctgct ccggcggcgc
     9001 aaccggctct ggctgcacgt agtgaaaaac gtgtcccgat gactcgcctg cgtaagcgtg
     9061 tggcagagcg tctgctggaa gcgaaaaact ccaccgccat gctgaccacg ttcaacgaag
     9121 tcaacatgaa gccgattatg gatctgcgta agcagtacgg tgaagcgttt gaaaaacgcc
     9181 acggcatccg tctgggcttt atgtccttct acgtgaaagc ggtggttgaa gccctgaaac
     9241 gttacccgga agtgaacgct tctatcgacg gcgatgacgt ggtttaccac aactatttcg
     9301 acgtcagcat ggcggtttct acgccgcgcg gcctggtgac gccggttctg cgtgatgtcg
     9361 ataccctcgg catggcagac atcgagaaga aaatcaaaga gctggcagtc aaaggccgtg
     9421 acggcaagct gaccgttgaa gatctgaccg gtggtaactt caccatcacc aacggtggtg
     9481 tgttcggttc cctgatgtct acgccgatca tcaacccgcc gcagagcgca attctgggta
     9541 tgcacgctat caaagatcgt ccgatggcgg tgaatggtca ggttgagatc ctgccgatga
     9601 tgtacctggc gctgtcctac gatcaccgtc tgatcgatgg tcgcgaatcc gtgggcttcc
     9661 tggtaacgat caaagagttg ctggaagatc cgacgcgtct gctgctggac gtgtagtagt
     9721 ttaagtttca cctgcactgt agaccggata aggcattatc gccttctccg gcaattgaag
     9781 cctgatgcga cgctgacgcg tcttatcagg cctacgggac caccaatgta ggtcggataa
     9841 ggcgctagcg ccgcatccga caagcgatgc ctgatgtgac ggttaacgtg tcttatcagg
     9901 cctacgggga ccaccaatgt aggtcggata aggcgcaagc gccgcatccg acaagcgatg
     9961 cctgatgtga cgtttaacgt gtcttatcag gcctatgggt gaccgacaat gcccggaagc
    10021 gatacgaaat attcggtcta cggtttaaaa gataacgatt actgaaggat ggacagaaca
    10081 catgaactta catgaatatc aggcaaaaca actttttgcc cgctatggct taccagcacc
    10141 ggtgggttat gcctgtacta ctccgcgcga agcagaagaa gccgcttcaa aaatcggtgc
    10201 cggtccgtgg gtagtgaaat gtcaggttca cgctggtggc cgcggtaaag cgggcggtgt
    10261 gaaagttgta aacagcaaag aagacatccg tgcttttgca gaaaactggc tgggcaagcg
    10321 tctggtaacg tatcaaacag atgccaatgg ccaaccggtt aaccagattc tggttgaagc
    10381 agcgaccgat atcgctaaag agctgtatct cggtgccgtt gttgaccgta gttcccgtcg
    10441 tgtggtcttt atggcctcca ccgaaggcgg cgtggaaatc gaaaaagtgg cggaagaaac
    10501 tccgcacctg atccataaag ttgcgcttga tccgctgact ggcccgatgc cgtatcaggg
    10561 acgcgagctg gcgttcaaac tgggtctgga aggtaaactg gttcagcagt tcaccaaaat
    10621 cttcatgggc ctggcgacca ttttcctgga gcgcgacctg gcgttgatcg aaatcaaccc
    10681 gctggtcatc accaaacagg gcgatctgat ttgcctcgac ggcaaactgg gcgctgacgg
    10741 caacgcactg ttccgccagc ctgatctgcg cgaaatgcgt gaccagtcgc aggaagatcc
    10801 gcgtgaagca caggctgcac agtgggaact gaactacgtt gcgctggacg gtaacatcgg
    10861 ttgtatggtt aacggcgcag gtctggcgat gggtacgatg gacatcgtta aactgcacgg
    10921 cggcgaaccg gctaacttcc ttgacgttgg cggcggcgca accaaagaac gtgtaaccga
    10981 agcgttcaaa atcatcctct ctgacgacaa agtgaaagcc gttctggtta acatcttcgg
    11041 cggtatcgtt cgttgcgacc tgatcgctga cggtatcatc ggcgcggtag cagaagtggg
    11101 tgttaacgta ccggtcgtgg tacgtctgga aggtaacaac gccgaactcg gcgcgaagaa
    11161 actggctgac agcggcctga atattattgc agcaaaaggt ctgacggatg cagctcagca
    11221 ggttgttgcc gcagtggagg ggaaataatg tccattttaa tcgataaaaa caccaaggtt
    11281 atctgccagg gctttaccgg tagccagggg actttccact cagaacaggc cattgcatac
    11341 ggcactaaaa tggttggcgg cgtaacccca ggtaaaggcg gcaccaccca cctcggcctg
    11401 ccggtgttca acaccgtgcg tgaagccgtt gctgccactg gcgctaccgc ttctgttatc
    11461 tacgtaccag caccgttctg caaagactcc attctggaag ccatcgacgc aggcatcaaa
    11521 ctgattatca ccatcactga aggcatcccg acgctggata tgctgaccgt gaaagtgaag
    11581 ctggatgaag caggcgttca tatgatcggc ccgaactgcc caggcgttat cactccgggt
    11641 gaatgcaaaa tcggtatcca gcctggtcac attcacaaac cgggtaaagt gggtatcgtt
    11701 tcccgttccg gtacactgac ctatgaagcg gttaaacaga ccacggatta cggtttcggt
    11761 cagtcgacct gtgtcggtat cggcggtgac ccgatcccgg gctctaactt tatcgacatt
    11821 ctcgaaatgt tcgaaaaaga tccgcagacc gaagcgatcg tgatgatcgg tgagatcggc
    11881 ggtagcgctg aagaagaagc agctgcgtac atcaaagagc acgttaccaa gccagttgtg
    11941 ggttacatcg ctggtgtgac tgcgccgaaa ggcaaacgta tgggccacgc gggtgccatc
    12001 attgccggtg ggaaagggac tgcggatgag aaattcgctg ctctggaagc cgcaggcgtg
    12061 aaaaccgttc gcagcctggc ggatatcggt gaagcactga aaactgttct gaaataaata
    12121 tctgtaataa gaaatagccc tcgccgcttc cctctacagg aatggcgaag ggctgtcggt
    12181 ttcgacatgg ttggccatcg tatgatggcc ttttttgtgc ttatcgcgat gattttcgct
    12241 gcgctatcag ggtaaattta tagtcatcgg tattaaaagc gttgcggcta tattcaaaca
    12301 cccgaccatc aactaaatat ccacgcgata ctttttcaag aatcggcttt gtctggctga
    12361 tattaagcag acggctcatc tcttcggttg gcatcagagg aatgatttcc tgttcgctac
    12421 gatcgataac cattttcttc acttcttcga taaagtgata tttcgaattt tccatgacct
    12481 gccaggtgag atccgggaac aacgcaagcg gcatccaggt ttcttccagc gccattggct
    12541 tttgcttgcg atagcgcacg cgcttcacat gccacacacg atcctgcggg gtgatttgta
    12601 gctgttgctg aagaaaatcg tcagccggaa tcacttcgaa tatcagaact tcactgtgtg
    12661 tatcgacgtg acggtccgac agtttttcat caaaactggt taactgaaaa atatcgtaat
    12721 tgacccgctc ttctttgacg taagtcccgc tgccctgaat gctttcgagg atctgctgct
    12781 cgactagctg gcgcaaagcc tgacgcaccg taacccggct gacgccaaac tctgtttgta
    12841 gcgctgattc agtgggtaac gcatcgccag gtttaagctc gccacgcgca atttgttcac
    12901 gaatgcgatc ggcaatctgc cggtataagg gcttgtgtcc catttttagt atctcattaa
    12961 tacgaattta accattatgc ccgataaatt catcctgtaa ataatacaaa cacaatacaa
    13021 ataatttcaa tcaagtgaaa ttgatcacat aatggtattg ttttatcggg cacactggcg
    13081 cgactataaa aacgatcaag tgaggatcat gatgaatctg acgactctga cccaccgcga
    13141 tgcgttgtgt ctgaatgcgc gctttaccag ccgtgaagag gccatccacg cgttgactca
    13201 acgtcttgct gctctgggga aaatttccag tactgagcaa tttctggaag aagtgtatcg
    13261 ccgtgaaagc cttggcccga ccgccttagg tgaagggttg gctgtgccgc atggcaaaac
    13321 tgctgcggta aaagaagcgg cgtttgcggt cgccacactc agcgagccgc ttcagtggga
    13381 aggcgttgat ggcccggaag cagttgattt agtggtgctg ctggcgattc cccccaatga
    13441 agcgggtact acgcatatgc aactgctgac agcgctgacc acgcgccttg cggatgatga
    13501 gattcgggcg cgtatacagt cggcgacgac gcctgatgag ttgctctcgg cgctggatga
    13561 caagggaggc acgcaacctt ctgcctcttt ttccaacgcg ccaactatcg tctgcgtaac
    13621 ggcctgtccg gcgggtattg ctcacaccta tatggctgcg gaatatctgg aaaaagccgg
    13681 acgcaaactc ggcgtaaatg tttacgttga aaaacaaggc gctaacggca ttgaagggcg
    13741 tttaacggcg gatcaactca atagtgcaac cgcctgtatt attgcggctg aagtcgccat
    13801 caaggagagt gagcgtttta atggcattcc cgcgctttca gtgcctgttg ccgagccgat
    13861 tcgccatgca gaagcgttga tccaacaagc gcttaccctc aagcgtagcg atgagacgcg
    13921 taccgtacag caagatacgc aaccggtgaa aagtgtcaaa acggagctga aacaggcact
    13981 gttgagcgga atctcttttg ccgtaccgtt gattgtcgcg gggggcacgg tgctggcggt
    14041 cgcggtatta ctgtcgcaaa tcttcgggct acaagatctg tttaatgaag aaaactcctg
    14101 gctgtggatg taccgcaagc tgggcggcgg gctgctcgga attttgatgg taccggtgct
    14161 cgcggcctat accgcctatt ctctggcaga taaaccggcg ttagcgccag gctttgcggc
    14221 tggacttgcc gccaacatga tcggctccgg gtttctcggc gcggtcgttg gcggattgat
    14281 agccggttac ttgatgcgct gggtgaaaaa tcacttgcgt cttagcagta aattcaatgg
    14341 attcctgact ttttatctct acccggtgct cggtacgttg ggagcgggca gtctgatgct
    14401 gtttgtggtg ggggaacctg tcgcctggat caataactcg cttaccgcct ggctgaacgg
    14461 tctgtcagga agtaacgcgc tgttgctggg tgccattctc ggttttatgt gttcctttga
    14521 ccttggaggg ccagtgaata aagccgctta tgcattctgc ctgggcgcaa tggcgaacgg
    14581 cgtttacggc ccgtatgcca ttttcgcctc cgtcaaaatg gtttcggcat ttaccgtaac
    14641 cgcttccacg atgctcgcac cgcgcctgtt taaagagttt gaaattgaga ccgggaaatc
    14701 cacctggctg ttagggctgg caggtattac cgaaggggcg atcccgatgg cgattgaaga
    14761 tccgctgcgg gttattggtt cgtttgtgct gggctctatg gtaacgggcg ctattgtcgg
    14821 tgcgatgaat atcggccttt cgacacccgg tgccggcatt ttctcgctct ttttacttca
    14881 tgataatggc gcgggcggtg ttatggcggc aattggctgg tttggcgcgg cattggtggg
    14941 ggctgcaatc tcgactgcaa ttctcctgat gtggcggcgt cacgcggtta agcatggcaa
    15001 ctatctgact gatggcgtaa tgccataaac aaaaaggaaa cgacgatgaa agcagtatct
    15061 cgcgttcaca tcaccccgca tatgcactgg gatcgagagt ggtatttcac caccgaagag
    15121 tcacgtattc tgctggtcaa taatatggaa gagatcctgt gccgactgga acaggacaac
    15181 gaatacaaat attacgtact cgacgggcaa acggcgatcc tcgaagatta tttcgcggtg
    15241 aaaccggaaa acaaagaccg tgtgaagaaa caggtagaag ccggcaagtt gattatcggc
    15301 ccctggtata cccagaccga taccacgatt gtttctgcgg aatccatcgt ccgtaatctg
    15361 atgtacggaa tgcgtgactg cctcgcgttt ggcgagccga tgaaaatagg ttatttacca
    15421 gattcctttg gcatgtccgg gcaactgccg catatctaca atggatttgg cattacccgc
    15481 accatgttct ggcgcggatg ttcggagcgc cacggtactg ataaaaccga gtttttgtgg
    15541 caaagcagtg acggtagcga agtgacggcg caggtgctgc cgctgggcta cgccatcggt
    15601 aagtacttac ctgccgacga aaacggatta cgtaaacgcc tcgacagtta ttttgacgtg
    15661 ctggaaaaag cgtctgtaac caaagagatt ttgctgccga atgggcatga ccagatgcca
    15721 ttgcagcaaa atatcttcga agtgatggat aagctacgtg agatctaccc tcaacgtaag
    15781 tttgtgatga gccgctttga agaggtattt gagaagatcg aagcgcagcg agataatctg
    15841 gcaaccctga aaggggaatt tattgatggc aaatatatgc gcgtgcatcg caccatcggt
    15901 tctacgcgta tggatatcaa aattgcccac gcgcgtattg aaaataagat tgttaatctg
    15961 ctggaaccgc tggcaacact ggcctggacg ttgggttttg aataccacca cggcttgctg
    16021 gagaaaatgt ggaaagagat cttaaaaaat catgcccacg acagtatcgg ctgctgctgt
    16081 agtgacaaag ttcatcgcga aatcgtcgcc cgcttcgaac tggctgaaga catggcggat
    16141 aatctgattc gtttctacat gcgcaaaatt gccgacaaca tgccgcagag cgacgccgac
    16201 aaactcgtcc tgtttaacct gatgccctgg ccgcgtgaag aagttatcaa caccactgtg
    16261 cggctgcgcg ccagccagtt taatttgcgg gacgatcgcg gtcagcctgt accgtatttt
    16321 attcgccatg cccgtgagat cgatccaggc ctaatcgatc ggcaaatagt tcattacggt
    16381 aattacgatc cctttatgga gtttgatata cagatcaacc agattgtccc ttctatgggc
    16441 tatcgcacgc tttatatcga agcgaatcag cctggcaacg taattgcggc aaaaagtgac
    16501 gctgaaggga tactggaaaa tgctttctgg caaattgcgc tcaatgagga tggttctctg
    16561 caactggtag ataaagacag cggtgtgcgc tatgaccggg tattgcaaat tgaagaaagc
    16621 tctgatgatg gtgatgaata tgactattca cccgcaaaag aagagtgggt aattaccgca
    16681 gcgaacgcga aaccgcaatg cgatattatt catgaagcct ggcagagcag ggctgttatc
    16741 cgctatgaca tggcagtgcc gctcaatttg tcagaacgca gcgcccggca atccactggc
    16801 agagtagggg tggtgttggt tgtcactctt agtcataaca gcaggcgtat tgatgtggat
    16861 atcaatcttg ataaccaggc tgacgatcat cgccttcgtg tcctggtccc tacacctttt
    16921 aacaccgaca gtgttctggc agatacgcag tttggttcgc taacgcgccc cgtgaacgac
    16981 agtgcaatga acaactggca gcaagaaggc tggaaagaag cgccggttcc ggtatggaat
    17041 atgctcaact atgttgcctt acaggaaggg cgtaacggca tggctgtctt tagcgaaggg
    17101 ttacgtgaat ttgaagtcat cggtgaagag aagaaaacct ttgccattac gttgctgcgt
    17161 ggcgtgggct tactgggcaa agaagatctg cttttaaggc ctgggcggcc ttcgggaatt
    17221 aaaatgccag tcccggactc acaactacgt ggtctgcttt cttgtcgcct aagtttattg
    17281 agttataccg gtacgccaac cgccgctggt gtagctcagc aggcgcgagc atggctgact
    17341 ccagtacagt gttacaacaa aatcccatgg gatgtgatga agctcaacaa agccggattc
    17401 aacgtgccgg aaagttatag tttgttgaaa atgcccccag tgggatgcct gataagcgca
    17461 cttaagaaag ctgaagaccg acaagaagtg attttacggc tgtttaatcc ggctgaatca
    17521 gcaacctgtg atgcgactgt tgctttcagt cgcgaggtga tttcttgctc agaaacgatg
    17581 atggatgaac acattaccac cgaggaaaat caaggttcaa atctatcggg gcctttttta
    17641 cccggccagt cacggacgtt cagttaccgg cttgcctgaa tagcaatcaa accgaagcca
    17701 catatgcgcg gccagattgt tgacaaaggg cgctttgttc atgccggata cggcatgaac
    17761 gctttattcg gtctacaaaa gcaggcaaat tcaatatatt gcagagatga tgtagacact
    17821 ggcaagcgta gcgcatcagg taattttgcg tttatcttca ctctcaagcc acgtatatgt
    17881 ggctttattt ttaacaaaat aat
//
LOCUS       DAPOAV010000087        17590 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.087, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000087 DAPOAV010000000
VERSION     DAPOAV010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17590
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.087"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            50..1189
                     /gene="arnB"
                     /locus_tag="RN951_003478"
     CDS             50..1189
                     /gene="arnB"
                     /locus_tag="RN951_003478"
                     /EC_number="2.6.1.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_024188371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-4-amino-4-deoxy-L-arabinose
                     aminotransferase"
                     /protein_id="HDX2528428.1"
                     /translation="MSEFLPFSRPAMGVEELAAVKEVLESGWLTTGPKNQALEQAFCQ
                     LTGNQHAIAVSSATAGMHITLMALEIGKGDEVITPSLTWVSTLNMISLLGATPVMVDV
                     DRDTLMVTPEAIESAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVG
                     TYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDR
                     QTWGRAPQAEVLTPGYKYNLTDINAAIALTQLAKLEHLNTRRREIAQQYQQALAALPF
                     QPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALKERGIGTGLHFRAAHTQKYYR
                     ERFPTLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ"
     gene            1193..2161
                     /gene="arnC"
                     /locus_tag="RN951_003479"
     CDS             1193..2161
                     /gene="arnC"
                     /locus_tag="RN951_003479"
                     /EC_number="2.4.2.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate
                     4-deoxy-4-formamido-L-arabinose transferase"
                     /protein_id="HDX2528429.1"
                     /translation="MFEIHPVKKVSVVIPVYNEQESLPELIRRTTTACESLGKEYEIL
                     LIDDGSSDNSAHMLVEASQAENSHIVSILLNRNYGQHSAIMAGFSHVTGDLIITLDAD
                     LQNPPEEIPRLVAKADEGYDVVGTVRQNRQDSWFRKTASKMINRLIQRTTGKAMGDYG
                     CMLRAYRRHIVDAMLHCHERSTFIPILANIFARRAIEIPVHHAEREFGESKYSFMRLI
                     NLMYDLVTCLTTTPLRMLSLLGSIIAIGGFSIAVLLVILRLTFGPQWAAEGVFMLFAV
                     LFTFIGAQFIGMGLLGEYIGRIYTDVRARPRYFVQQVIRPSSKENE"
     gene            2161..4143
                     /gene="arnA"
                     /locus_tag="RN951_003480"
     CDS             2161..4143
                     /gene="arnA"
                     /locus_tag="RN951_003480"
                     /EC_number="1.1.1.305"
                     /EC_number="2.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-4-amino-4-deoxy-L-arabinose
                     formyltransferase/UDP-glucuronic acid oxidase ArnA"
                     /protein_id="HDX2528430.1"
                     /translation="MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGS
                     VARLAAERGIPVYATDDVNHPLWVERIAQLSPDVIFSFYYRHLICDEILQLAPAGAFN
                     LHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRIAIAPDDIAIT
                     LHHKLCHAARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTPDDSFLEWHKPASVLH
                     NMVRAVADPWPGAFSYVGNQKFTVWSSRVHPHASKAQPGSVISVAPLLIACGDGALEI
                     VTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACTARRRTRVLILGVNGFIGNHLTER
                     LLREDHYEVYGLDIGSDAISRFLNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAI
                     ATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSN
                     LIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGS
                     SRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIG
                     NPENEASIEELGEMLLASFEKHPLRHHFPPFAGFRVVESSSYYGKGYQDVEHRKPSIR
                     NAHRCLDWEPKIDMQETIDETLDFFLRTVDLTDKPS"
     gene            4140..5030
                     /locus_tag="RN951_003481"
     CDS             4140..5030
                     /locus_tag="RN951_003481"
                     /EC_number="3.5.1.n3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-deoxy-4-formamido-L-arabinose-
                     phosphoundecaprenol deformylase"
                     /protein_id="HDX2528431.1"
                     /translation="MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDN
                     MGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIIREAAKHHE
                     VGLHAWDHHAWQARSGNWDRQTMIDDIARGLRTLEEIIGQPVTCSAAAGWRADQKVIE
                     AKEAFHLRYNSDCRGAMPFRPLLESGNPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLL
                     NRILRDKGTPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSETLPLGQVV
                     RGNIAGREGWLGCQQIAGSR"
     gene            5030..6682
                     /gene="arnT"
                     /locus_tag="RN951_003482"
     CDS             5030..6682
                     /gene="arnT"
                     /locus_tag="RN951_003482"
                     /EC_number="2.4.2.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A)
                     4-amino-4-deoxy-L-arabinosyltransferase"
                     /protein_id="HDX2528432.1"
                     /translation="MKSVRYLIGLFAFIACYYLLPISTRLLWQPDETRYAEISREMLA
                     SGDWIVPHLLGLRYFEKPIAGYWINSIGQWLFGANNFGVRAGVIFATLLTAALVTWFT
                     LRLWRDKRLALLATVIYLSLFIVYAIGTYAVLDPFIAFWLVAGMCSFWLAMQAQTWKG
                     KSAGFLLLGITCGMGVMTKGFLALAVPVLSVLPWVATQKRWKDLFIYGWLAVISCVLT
                     VLPWGLAISQREPDFWHYFFWVEHIQRFALDDAQHRAPFWYYVPVIIAGSLPWLGLLP
                     GALYTGWKNRKHSATVYLLSWTIMPLLFFSVAKGKLPTYILSCFASLAMLMAHYALLA
                     AKNNPLALRINGWINIAFGVTGIIATFVVSPWGPMNTPVWQTFESYKVFCAWSIFSLW
                     AFFGWYTLTNVEKTWPFAALCPLGLALLVGFSIPDRVMEGKHPQFFVEMTQESLQPSR
                     YILTDSVGVAAGLAWSLQRDDIIMYRQTGELKYGLNYPDAKGRFVSGDEFANWLNQHR
                     QEGIITLVLSVDRDEDINSLAIPPADAIDRQERLVLIQYRPK"
     gene            6679..7014
                     /gene="arnE"
                     /locus_tag="RN951_003483"
     CDS             6679..7014
                     /gene="arnE"
                     /locus_tag="RN951_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnE"
                     /protein_id="HDX2528433.1"
                     /translation="MIWLTLVFASLLSVAGQLCQKQATCFVAINKRRKHIVLWLGLAL
                     ACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSPRHWCGVAFIIG
                     GIVILGSTV"
     gene            7014..7400
                     /gene="arnF"
                     /locus_tag="RN951_003484"
     CDS             7014..7400
                     /gene="arnF"
                     /locus_tag="RN951_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311173.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnF"
                     /protein_id="HDX2528434.1"
                     /translation="MGLIWGLFSVIIASVAQLSLGFAASHLPPMTHLWDFIAALLAFG
                     LDARILLLGLLGYLLSVFCWYKTLHKLALSKAYALLSMSYVLVWIASMVLPGWEGTFS
                     LKALLGVACIMSGLMLIFLPTTKQRY"
     gene            complement(7394..7660)
                     /gene="pmrD"
                     /locus_tag="RN951_003485"
     CDS             complement(7394..7660)
                     /gene="pmrD"
                     /locus_tag="RN951_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416762.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction protein PmrD"
                     /protein_id="HDX2528435.1"
                     /translation="MEWLVKKSCCNKQDNRHVLMLCDAGGAIKMIAEVKSDFAVKVGD
                     LLSPLQNALYCINREKLHTVKVLSASSYSPDEWERQCTAAGKTQ"
     gene            complement(7770..9125)
                     /gene="menE"
                     /locus_tag="RN951_003486"
     CDS             complement(7770..9125)
                     /gene="menE"
                     /locus_tag="RN951_003486"
                     /EC_number="6.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate--CoA ligase"
                     /protein_id="HDX2528436.1"
                     /translation="MIFSDWPWRHWRQVRGEAIALRLNDEQLNWRELCARVDELASGF
                     AAQGVVEGSGVMLRAWNTPQTLLAWLALLQCGARVLPVNPQLPQPLLEELLPNLTLQF
                     ALVPDGENTFPALTSLHIQRVEGAHAATWQPTRLCSMTLTSGSTGLPKAAVHTYQAHL
                     ASAEGVLSLIPFGDHDDWLLSLPLFHVSGQGIMWRWLYAGARMTVRDKQPLEQMLAGC
                     THASLVPTQLWRLLVNRSSVSLKAVLLGGAAIPVELTEQAREQGIRCFCGYGLTEFAS
                     TVCAKEADGLADVGSPLPGREVKIVNNEVWLRAASMAEGYWRNGQLVSLVNDEGWYAT
                     RDRGEMHNGKLTIVGRLDNLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKEFGH
                     RPVAVVEYDQQTVDLGEWVKDKLARFQQPVRWLTLPPELKNGGIKISRQALKEWVQRQ
                     Q"
     gene            complement(9122..10084)
                     /gene="menC"
                     /locus_tag="RN951_003487"
     CDS             complement(9122..10084)
                     /gene="menC"
                     /locus_tag="RN951_003487"
                     /EC_number="4.2.1.113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate synthase"
                     /protein_id="HDX2528437.1"
                     /translation="MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGE
                     ISPLPGFSQETWEEAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELADTLPQAA
                     NYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRL
                     DANRAWTPLKGQQFAKYVNTDYRHRIAFLEEPCKTRDDSRAFARETGIAIAWDESLRE
                     PDFAFVAEEGVRAVVIKPTLTGSLEKVREQVQAAHALGLTAVISSSIESSLGLTQLAR
                     IAAWLTPDTIPGLDTLDLMQAQQVRRWPGSTLPVVEVDALERLL"
     gene            complement(10084..10941)
                     /gene="menB"
                     /locus_tag="RN951_003488"
     CDS             complement(10084..10941)
                     /gene="menB"
                     /locus_tag="RN951_003488"
                     /EC_number="4.1.3.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001641973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA synthase"
                     /protein_id="HDX2528438.1"
                     /translation="MIYPDEAMLYAPVEWHDCSEGFEDIRYEKSTDGIAKITINRPQV
                     RNAFRPLTVKEMIQALADARYDDNVGVIILTGAGDKAFCSGGDQKVRGDYGGYKDDSG
                     VHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAADNAIFGQTGPKVG
                     SFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGLVNTVVPLADLEKETVRWC
                     REMLQNSPMALRCLKAALNADCDGQAGLQELAGNATMLFYMTEEGQEGRNAFNQKRQP
                     DFSKFKRNP"
     gene            complement(10956..11714)
                     /gene="menH"
                     /locus_tag="RN951_003489"
     CDS             complement(10956..11714)
                     /gene="menH"
                     /locus_tag="RN951_003489"
                     /EC_number="4.2.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-6-hydroxy-2,
                     4-cyclohexadiene-1-carboxylate synthase"
                     /protein_id="HDX2528439.1"
                     /translation="MILHAQAKHGKPGLPWLVFLHGFSGDCHEWQEVGEAFADYSRLY
                     VDLPGHGGSAAISVDGFDDVTDLLRKTLVSYNILDFWLVGYSLGGRVAMMAACQGLAG
                     LCGVIVEGGHPGLQNAEQRAERQRSDRQWAQRFCTEPLTAVFADWYQQPVFASLNDDQ
                     RRELVVLRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAA
                     ELAADCHVIPRAGHNAHRENPAGVIASLAQILRF"
     gene            complement(11711..13381)
                     /gene="menD"
                     /locus_tag="RN951_003490"
     CDS             complement(11711..13381)
                     /gene="menD"
                     /locus_tag="RN951_003490"
                     /EC_number="2.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
                     cyclohexene-1-carboxylic-acid synthase"
                     /protein_id="HDX2528440.1"
                     /translation="MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAEN
                     STFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLIL
                     LTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTRDIPARWLVSTIDHALGTLH
                     AGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWR
                     QKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSEL
                     QQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWL
                     ELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRICDYLPEQGQLFVGNSL
                     VVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLN
                     ALALLRQVSAPLVLIVVNNNGGQIFSLLPTPQSERERFYLMPQNVHFEHAAAMFELKY
                     HRPQNWQELETAFADAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL"
     gene            complement(13470..14765)
                     /gene="menF"
                     /locus_tag="RN951_003491"
     CDS             complement(13470..14765)
                     /gene="menF"
                     /locus_tag="RN951_003491"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416768.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase MenF"
                     /protein_id="HDX2528441.1"
                     /translation="MQSLTTALENLLRHLSQEIPATPGIRVIDIPFPLKDAFDALSWL
                     ASQQTYPQFYWQQRNGDEEAAVLGAITRFTSLDQAQRFLRQHPEHADLRIWGLNAFDP
                     SQGNLLLPRLEWRRCGGKATLRLTLFSESSLQHDAIQAKEFIATLVSIKPLPGLHLTT
                     TREQHWPDKTGWTQLIELATKTIAEGELDKVVLARATDLYFASPVNAAAMMAASRRLN
                     LNCYHFYMAFDGENAFLGSSPERLWRRRDKALRTEALAGTVANNPDDKQAQQLGEWLM
                     ADDKNQRENMLVVEDICQRLQADTQTLDVLPPQVLRLRKVQHLRRCIWTSLNKADDVI
                     CLHQLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAGYLSLQQSEFCVSLRSAKIS
                     GNVVRLYAGAGIVRGSDPEQEWQEIDNKAAGLRTLLQME"
     gene            complement(14844..15149)
                     /gene="elaB"
                     /locus_tag="RN951_003492"
     CDS             complement(14844..15149)
                     /gene="elaB"
                     /locus_tag="RN951_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein ElaB"
                     /protein_id="HDX2528442.1"
                     /translation="MSNQFGDTRIDDDLTLLSETLEEVLRSSGDPADQKYVELKARAE
                     KALDDVKKRVSQASDSYYYRAKQAVYRADDYVHEKPWQGIGVGAAVGLVLGLLLARR"
     gene            complement(15204..15665)
                     /locus_tag="RN951_003493"
     CDS             complement(15204..15665)
                     /locus_tag="RN951_003493"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDX2528443.1"
                     /translation="MIEWQDLHHSKLSVSQLYALLQLRCAVFVVEQNCPYQDIDGDDL
                     TGDNRHILGWKNDELVAYARILKSDDDLEPVVIGRVIVSEALRGEKVGQQLMSKTLET
                     CTHHWPDKPVYLGAQAHLQNFYQSFGFIPVTEVYEEDGIPHIGMAREVIQA"
     gene            15730..16647
                     /gene="rbn"
                     /locus_tag="RN951_003494"
     CDS             15730..16647
                     /gene="rbn"
                     /locus_tag="RN951_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416771.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease BN"
                     /protein_id="HDX2528444.1"
                     /translation="MELIFLGTSAGVPTRTRNVTAILLNLQHPTQSGLWLFDCGEGTQ
                     HQLLHTAFNPGKLDKIFISHLHGDHLFGLPGLLCSRSMSGIIQPLTIYGPQGIREFVE
                     TALRISGSWTDYPLEIVEIGAGEILDDGLRKVTAYPLEHPLECYGYRIEEHDKPGALN
                     AQALKAAGVPPGPLFQELKAGKTITLEDGRQINGADYLAAPVPGKALAIFGDTGPCDA
                     ALDLAKGVDVMVHEATLDITMEAKANSRGHSSTRQAATLAREAGVGKLIITHVSSRYD
                     DKGCQHLLRECRSIFPATELANDFTVFNV"
     gene            16835..>17590
                     /locus_tag="RN951_003495"
     CDS             16835..>17590
                     /locus_tag="RN951_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416772.1"
                     /note="ElaD; specific cysteine protease which targets
                     ubiquitin and ubiquitin-like proteins covalently bound to
                     target proteins; SseL in Salmonella is required for
                     macrophage killing and virulence, and it is secreted by
                     the salmonella pathogenicity island 2 type III secretion
                     system; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deubiquitinase"
                     /protein_id="HDX2528445.1"
                     /translation="MMVTVVSNYCQLSQTQLSQTFAEKFTVTEELLQSLKKTALSGDE
                     ESIELLHNIALGYDEFGKKAEDILYHIVRNPTNETLSIIRLIKNACLKLYNLAHTATN
                     SHLKPTGPDTSDVLLFKKLFSPSKLMTIIGDEIPLISEKQSLSKVLLNDENNELSDDT
                     NFWDKNRQLTTDEIACYLQKIAANAKNTQVNYPTGLYVPYSTRTHLEDALNENIKSDP
                     SWPNEVQLFPINTGGHWILVSLQKIVNKKNNKLQ"
BASE COUNT         4150 a         4725 c         4433 g         4282 t
ORIGIN      
        1 tttatagcaa atataagtgg acaggtattc aatggcggaa ggaaaagcaa tgtcagaatt
       61 tttgcctttt tcgcgaccag caatgggcgt ggaggaactc gctgcagtta aagaggttct
      121 cgaatccggt tggctcacaa ccggtccgaa gaatcaggcg cttgagcaag ccttttgcca
      181 gttgacggga aatcagcatg ccatcgcggt cagttcagcc accgccggaa tgcatatcac
      241 gctaatggcg ttggaaattg gcaagggcga tgaagtgatt acgccttccc tgacctgggt
      301 ttcaaccctc aatatgattt ccttgttggg tgcaacgccg gtaatggtgg atgtcgaccg
      361 cgatacgctg atggtcacgc ctgaagcgat cgagtcagcc ataacgccac gcactaaagc
      421 catcattccg gtgcattatg ccggtgcgcc agcagatatt gacgccattc gcgccattgg
      481 cgaacgttac ggcatcgcag ttatcgaaga tgctgcccat gccgtcggta cgtattacaa
      541 agggcgacat attggcgcaa aaggtaccgc tattttttca tttcatgcca ttaaaaatat
      601 tacctgtgcg gaaggtggcc tgattgtaac tgataatgaa aaccttgccc gccagctacg
      661 gatgctgaaa tttcacggtc tgggtgtcga tgcctatgac agacaaacct ggggccgtgc
      721 accgcaggct gaagtcttaa caccgggcta taagtacaat ctgaccgata ttaacgccgc
      781 aattgccctg acacagttag caaaattaga gcacctcaac acccgtcggc gcgaaattgc
      841 ccagcaatat cagcaagcac tggcagctct cccctttcag ccattaagcc ttcccgcctg
      901 gccgcacgtt cacgcctggc atctgtttat tattcgtgtc gatgaacaac gttgtggtat
      961 cagtcgcgat gcgttgatgg aagcgttaaa agaaagaggc attggtaccg ggttacattt
     1021 ccgcgccgct cacacacaaa aatattatcg cgagcgtttt cccacgctgt cgttaccgaa
     1081 taccgaatgg aatagcgaac gcatctgttc tttgccgctg ttcccggata tgactaccgc
     1141 cgatgccgac cgtgtcatca cagcccttca gcaactcgca ggacaataag ccatgtttga
     1201 aatccaccct gttaagaaag tctcggtggt tattcccgtt tataacgagc aggaaagctt
     1261 accggaatta atcaggcgca ccaccacagc ctgtgaatcg ttggggaaag agtatgagat
     1321 cctgctgatt gatgacggca gtagcgataa ttccgcgcat atgctggtcg aagcctcaca
     1381 agcggagaac agccatattg tgtctatttt gcttaaccgc aattacgggc aacattcagc
     1441 gattatggcg ggattcagtc acgttaccgg cgacttaatt attacccttg atgccgatct
     1501 ccagaatccg ccagaagaaa tcccccgcct ggtggcaaaa gccgatgaag gttacgacgt
     1561 ggtagggact gtacgccaga accgccagga cagctggttt cgtaaaacag cttcgaagat
     1621 gattaaccgg cttattcagc gcaccaccgg caaagcgatg ggtgactacg gttgtatgct
     1681 gcgcgcctat cgccgtcata ttgtcgatgc gatgttgcac tgccatgaac gtagcacctt
     1741 tatcccgatt ctggcgaata tcttcgcccg ccgtgccatt gaaattccag tacatcatgc
     1801 cgagcgtgag tttggtgaat ccaaatacag ttttatgcgc ctgattaatt tgatgtacga
     1861 cctggtgacc tgccttacca caacgccgct acgtatgctg agtctgctcg gcagcattat
     1921 tgcgattgga ggttttagca ttgcggtgct gctggtgatt ttacgcctga ccttcggacc
     1981 acaatgggcg gcagaaggcg tctttatgct atttgccgtg ctgtttactt ttattggcgc
     2041 tcagtttatc ggcatgggat tactcggtga atatatcggc aggatctaca ccgatgtccg
     2101 cgcccgcccc cgctattttg ttcagcaagt tatccgtcca tccagcaagg aaaatgaata
     2161 atgaaaaccg tcgtttttgc ctaccacgat atgggatgcc tcggtattga agctctgctg
     2221 gctgccggtt acgaaattag cgccattttt acccataccg ataatcccgg tgaaaaagcc
     2281 ttttatggtt cggtggctcg tctggcagcg gaaagaggca ttccggttta tgcgacggat
     2341 gacgttaatc atccgctgtg ggtggaacgc attgcccaac tgtcgccaga tgtgattttc
     2401 tctttttatt atcgccatct tatttgcgac gaaattttgc agctcgctcc cgcaggtgca
     2461 tttaatctgc atggttcgct gttaccaaaa tatcgtggtc gcgcgccgct gaactgggtg
     2521 ctggtcaacg gtgaaacgga aactggcgtt acattgcacc gaatggtgaa acgtgccgat
     2581 gccggggcca ttgtggcgca actgcgcatt gccattgcgc cagacgatat cgctattacg
     2641 ctgcatcata aattgtgcca tgccgcgcgc cagctactgg aacagacatt acccgccatt
     2701 aaacacggta atattctgga aatcgcccag cgcgaaaacg aagccacctg ttttggtcgc
     2761 agaacgccgg atgacagttt ccttgaatgg cataaaccgg catccgtact gcacaacatg
     2821 gtacgtgccg ttgccgatcc gtggccgggt gccttcagct atgttggcaa tcagaaattc
     2881 accgtctggt cgtcgcgtgt tcatcctcat gccagcaaag cacagccggg gagcgtgatt
     2941 tctgttgcgc cactgctgat tgcctgtggc gatggcgcgc tggaaatcgt caccggacag
     3001 gcgggcgacg gcattactat gcagggctcg caattagcgc agacgctggg cctggtgcaa
     3061 ggttcacgct tgaatagcca gcctgcctgc accgcccgac gccgtacccg ggtactcatc
     3121 ctcggggtga atggctttat tggcaaccat ctgacagaac gcctgctgcg cgaagatcat
     3181 tatgaagttt acggtctgga tattggcagc gatgcgataa gccgttttct gaatcatccg
     3241 cattttcact ttgttgaagg cgatatcagt attcattccg aatggattga gtatcatgtc
     3301 aaaaaatgtg atgtcgtctt gccgctggtg gcgatagcca cgccgattga atatacccgc
     3361 aacccgctgc gcgtatttga actcgatttt gaagagaatc tgcgcattat ccgctactgc
     3421 gtgaagtacc gtaagcgaat catcttcccg tcaacttcag aagtttatgg gatgtgtagc
     3481 gataaatact tcgatgagga ccattctaat ttaatcgtcg gcccggtgaa taaaccacgc
     3541 tggatttatt cggtgtcaaa acaattactt gatcgggtta tctgggccta tggcgaaaaa
     3601 gagggtttac agttcaccct cttccgcccg tttaactgga tgggaccacg actggataac
     3661 cttaatgcag cgcgaattgg cagctcccgc gctattacgc aactcattct caatctggta
     3721 gaaggttcac cgattaagct gattgatggc ggaaaacaaa aacgctgctt tactgatatt
     3781 cgcgatggta tcgaggcgtt ataccgcatt atcgaaaatg cgggaaatcg ctgcgacggt
     3841 gaaattatca acattggcaa tcctgagaac gaagcgagca ttgaggaact gggcgagatg
     3901 ctgctggcga gcttcgaaaa acatccgctg cgccatcatt tcccaccgtt tgcgggcttt
     3961 cgcgttgtcg aaagtagcag ctactacggc aaaggatatc aggacgtaga gcatcgtaaa
     4021 ccgagcatcc gcaatgccca ccgctgcctg gactgggagc cgaaaattga tatgcaggaa
     4081 accatcgacg aaacgctgga tttcttcctg cgcaccgttg atcttacgga taaaccatca
     4141 tgaccaaagt aggcttacgc attgatgtcg atacctttcg tggcacccgt gaaggcgtgc
     4201 cgcgtctgct ggaaatcttg agtaagcata atattcaggc cagcattttt ttcagcgtcg
     4261 gcccggacaa tatgggccgc catctctggc gactggtgaa gccacagttt ttgtggaaga
     4321 tgctgcgctc aaatgcggca tcgctttatg gctgggatat tttactggca ggtacggcct
     4381 ggccaggtaa agagattggt catgccaatg ccgatatcat tcgtgaagcg gctaaacatc
     4441 acgaagtcgg cctgcacgcc tgggatcacc atgcctggca agcccgtagc ggtaactggg
     4501 atcggcaaac aatgatcgac gatattgcac gcggtcttcg cactctggaa gagattatcg
     4561 gtcaaccggt aacctgttct gccgctgcgg gctggcgtgc cgaccagaag gtgatcgaag
     4621 caaaagaagc gttccatttg cgctacaaca gcgattgtcg tggggccatg ccgttccgtc
     4681 cattgctcga atcaggaaac cctggcactg cgcaaattcc ggtgacctta cccacctggg
     4741 atgaagtgat tggtcgggat gtgaaagcag aagattttaa cggttggtta ctcaaccgca
     4801 tcctgcgaga taaaggcacg ccggtttata ccattcatgc agaagttgaa ggctgcgctt
     4861 atcagcataa ttttgtggat ctcctcaaac gcgcagctca ggaaggcgtg acattttgcc
     4921 ctttaagcga actgttatca gagacgttgc cgctcggaca agttgttcgc ggaaatattg
     4981 ccggacgtga aggctggctg ggttgccaac aaattgcggg tagtcgctga tgaaatcggt
     5041 acgttacctt atcggcctct tcgcgtttat tgcctgctat tacctgttac cgatcagcac
     5101 gcgtctgctc tggcaacccg atgaaacgcg ttatgcggaa atcagtcgag aaatgctggc
     5161 atccggcgac tggattgtgc cccatctgtt agggctacgt tatttcgaaa aacccattgc
     5221 cggatactgg attaacagca ttgggcaatg gctatttggc gcgaataact ttggtgtgcg
     5281 ggcaggcgtt atctttgcga ccctgttaac tgccgcgctg gtgacctggt ttactctgcg
     5341 cttatggcgc gataaacgtc tggctctact cgccacagta atttatctct cattgtttat
     5401 tgtctatgcc atcggcactt atgccgtgct cgatccgttt attgcattct ggctggtggc
     5461 gggaatgtgc agcttctggc tggcaatgca ggcacagacg tggaaaggca aaagcgcagg
     5521 atttttactg ctgggaatca cctgcggcat gggggtgatg accaaaggtt ttctcgccct
     5581 tgccgtgccg gtattaagcg tgctgccatg ggtagcgacg caaaaacgct ggaaagatct
     5641 ctttatttac ggctggctgg cggttatcag ttgcgtactg acggttctcc cttggggact
     5701 ggcgatatcg cagcgggagc ctgacttctg gcactatttt ttctgggttg agcatattca
     5761 acgctttgca ctggatgatg cccaacatag agctccgttc tggtactacg tgccggtcat
     5821 cattgccggt agcctgccgt ggctgggatt actccccggt gcactgtaca caggctggaa
     5881 aaaccgcaag cattccgcaa ccgtctattt gttgagctgg acgataatgc cgctgctgtt
     5941 tttctccgtc gctaaaggta aattgcccac ctatattctt tcctgctttg catctctggc
     6001 aatgctgatg gcgcattacg ctttgctggc agcaaaaaat aatcctctgg cgctgcggat
     6061 taatggctgg attaacatcg cttttggcgt cactggcatt attgccacat ttgtggtctc
     6121 cccgtgggga ccaatgaaca cgccggtgtg gcaaaccttc gagagctata aagtcttttg
     6181 tgcctggtcg attttttcgc tatgggcatt tttcggctgg tacaccttaa caaacgtcga
     6241 aaagacctgg ccttttgccg cgctttgccc gctggggctg gcgttgctgg taggattttc
     6301 aattcctgac agagttatgg aaggaaaaca tccgcaattt tttgtcgaga tgacacaaga
     6361 atcacttcag ccaagccgct atattcttac tgatagcgtc ggtgttgccg caggtctggc
     6421 atggagcctg caacgcgatg acatcatcat gtatcgccag acaggtgagt tgaaatacgg
     6481 ccttaattat ccggatgcga aagggagatt tgtcagcggt gatgagttcg caaactggct
     6541 taatcaacat cgtcaggagg ggattattac tctcgtgctt tcggttgacc gcgatgaaga
     6601 tatcaacagt ctcgccattc cgcccgcaga tgccatcgat cgtcaggagc gtctggtgct
     6661 gattcagtat cgtcccaaat gatctggcta acattagtct ttgccagctt gcttagcgtt
     6721 gccgggcagt tgtgtcagaa acaggcaacc tgctttgtgg cgataaacaa acggcgcaaa
     6781 catatcgtgc tgtggctggg actggcgctg gcttgtcttg gtcttgccat ggtgctctgg
     6841 ctgctggtct tgcagaacgt accggtaggc attgcctacc cgatgttaag tctgaatttt
     6901 gtctgggtga cgctggctgc agtaaaactg tggcacgaac cggtatcgcc gcgtcactgg
     6961 tgtggggtgg cgttcattat tggtggcatt gtgatcctcg ggagtacggt gtaatgggcc
     7021 tgatatgggg attattcagc gtcattattg cctcagttgc gcaattaagt ctgggttttg
     7081 cggcaagtca tctgccgccg atgacgcact tatgggattt tatcgcggct ctgttagctt
     7141 ttggcctgga tgcccggata ctgttactcg ggctgctggg ttatctgctt tccgtttttt
     7201 gttggtataa aacgctacat aaacttgcgc taagcaaagc ctatgccttg ctcagtatga
     7261 gttatgtgct ggtatggatt gcttcaatgg tacttcccgg ctgggaaggg actttttcgc
     7321 tgaaagcact actgggagta gcctgtatta tgagcgggtt gatgctgatt ttcctgccca
     7381 cgacaaaaca acgttactga gttttccctg ccgctgtaca ctgccgttcc cactcatcgg
     7441 ggctataact gcttgccgag aggactttca ccgtatgcag cttttcacga ttaatacaat
     7501 aaagcgcatt ctgcaaaggc gagagtaaat cccccacttt cacggcgaag tcactcttca
     7561 cttcggcgat catttttatc gcgccgccag catcgcagag cataagtaca tgtctgttat
     7621 cttgtttatt gcagcacgat tttttgacca gccattccat tgcattatcc tgtttgctaa
     7681 gagttttcac atcaatttac agattaacag ataaactctt tatcaacggc aatggaatgg
     7741 cagaaatgag aagtgaaacg gagggttaat tattgctgac gttgcaccca ctcttttagc
     7801 gcctgacgtg aaattttaat accgccgttt ttaagctccg gcggtaaagt cagccagcgc
     7861 accggttgtt gaaaacgagc cagcttatct ttcacccatt cgccaagatc aacggtttgc
     7921 tggtcatact ccaccaccgc taccggccga tgaccaaact ccttgtcggc aacgggaacg
     7981 ataaacacct gcaaaaccgc aggatgtgca gcaataacac gctcgacttc ttccggctga
     8041 ataccctcac cgccactgaa gaacagattg tctaaacgtc cgacaatggt cagcttgcca
     8101 ttatgcatct caccgcgatc gcgcgtagcg taccagcctt cgtcattaac cagtgaaacc
     8161 agttgcccgt tacgccagta accttctgcc atactggcag cccgcagcca cacttcatta
     8221 ttaacgattt tcacttcccg acccggcagc ggcgaaccaa cgtctgccag gccgtcggct
     8281 tctttcgcac acaccgtgga ggcaaactcg gtcagaccat agccgcaaaa gcaacgaatc
     8341 ccctgctcgc gcgcctgttc cgtcaactcg accgggatag ccgcgccgcc aagtaacacc
     8401 gctttcaggg aaacggaact gcggttaacc agcaaacgcc agagttgtgt tggcaccagt
     8461 gaagcgtgag tacagcctgc cagcatttgc tccaatggct gtttatcacg caccgtcatc
     8521 cgcgcaccag cgtataacca gcgccacata attccctgac cggagacgtg aaacagcggt
     8581 aaagagagca accagtcatc gtgatcgcca aacggaatca acgataacac cccttcggca
     8641 ctggcaagat gggcctgata agtatggaca gcggctttcg gcaacccggt agaacccgag
     8701 gtcaacgtca ttgagcacag acgcgtcggc tgccacgtag cggcatgtgc gccttcaacc
     8761 cgctgaatgt gcagcgacgt taacgccgga aacgtgtttt ccccatccgg caccagcgca
     8821 aattgcagcg tcagattggg cagcaattct tcaagcaacg gttgcggcag ctgagggttc
     8881 acgggcaaca cccgcgcccc gcattgcagt aacgccagcc aggcgagcag cgtttgcggc
     8941 gtattccacg cccgcaacat cacgccgctg ccctcaacaa cgccctgcgc cgcaaagcct
     9001 gaggctaatt catcgacgcg agcacaaagc tcgcgccagt taagttgctc gtcattaaga
     9061 cgtaaggcga tggcttctcc ccgcacttgc cgccagtgac gccacggcca gtcagagaag
     9121 atcataacaa ccgctccagt gcatcaactt ccacgacagg cagcgtgcta cccggccagc
     9181 gacgtacctg ctgcgcctgc atcagatcca gcgtgtccag ccctggaatg gtgtccggcg
     9241 ttaaccaggc ggcaatccgc gccagttgcg ttaagcctaa gctcgattca atggaagaac
     9301 tgatcaccgc cgtcagcccc agcgcgtgcg ccgcctgtac ctgctcgcgt actttctcca
     9361 gactgcccgt gagcgtgggt ttgataacta ccgcgcgcac gccctcttca gccacaaagg
     9421 caaaatccgg ctcgcgcagg ctttcatccc aggcaatggc aatgccggtt tcacgggcaa
     9481 acgctcgcga atcatcgcgg gttttgcacg gctcttcgag aaacgcgatg cggtggcgat
     9541 aatccgtgtt aacatatttg gcaaactgct ggcctttcag cggtgtccag gcgcgatttg
     9601 cgtcaagacg caaatgcaga tccggaattg cctccagcaa cagattaacc accatgccgt
     9661 cgcgcacggc ttcgtacaat cccactttga ccttcgccac tttctcgcct ggcatatcag
     9721 caagtttgag gatcagatcg tcaggatcgc cattacacag tggtgccgca cggtaattgg
     9781 ccgcctgcgg gagcgtatct gccagctccg ccaatgcaca gcttacgcca aaggcaacgg
     9841 aaggcatctg cggtagctcg caatcgcctg ccagccagtt atttacccag gcaagcagca
     9901 cgctttgcgc ctcttcccag gtttcctggc tgaagcccgg cagtggggag atctcccccc
     9961 acccttcgcg ctcgccctca cgcaggcaaa cgtacagccc gtcgcgggtt tttaaccgcc
    10021 tgtcgcgcag aaccaccccc gcgtccatgg ggatctgcca gcggtatacc tgcgcgctac
    10081 gcattacgga ttccgtttaa atttgctgaa atcaggctga cgtttctggt tgaaagcgtt
    10141 gcgaccttcc tgaccttctt ccgtcatgta gaacagcatg gtggcgttgc ccgccagctc
    10201 ttgcagcccc gcctgcccgt cacagtcggc gttcagcgca gctttcaggc agcgcagcgc
    10261 catcgggctg ttttgcagca tttcgcggca ccaacggacg gtttcttttt ccagatccgc
    10321 cagcggtacc acggtgttga caaggcccat atccagcgcc tgttttgcgt cgtactgacg
    10381 gcacaggaac cagatttctc gcgctttttt ctgcccgacg atacgagcca tgtaggaagc
    10441 gccccagccg ccgtcgaagg aaccgacttt cgggccagtc tgaccgaaga tggcattatc
    10501 tgccgcgata gtcaggtcgc acatcatgtg cagaacgtga ccgccgccga tggagtagcc
    10561 agccaccatc gcgacaaccg gtttcggaca ggtacggatc tgacgctgga agtccagcac
    10621 gttcaggtga tgtacgccgg aatcatcttt atagccgccg taatcgccac gcactttctg
    10681 gtcaccgccg gagcagaacg ctttatcgcc tgcgccagtc agaatgatca cgccgacgtt
    10741 gtcgtcataa cgcgcatctg ccagtgcctg gatcatctct tttaccgtca gaggacggaa
    10801 ggcattgcgc acctgcggac gattaatggt gatttttgcg ataccgtcgg tggatttttc
    10861 ataacgaatg tcctcaaagc cttcggagca gtcgtgccat tcaaccggtg cgtaaagcat
    10921 tgcttcatca ggataaatca tattgtgtcc tttagtcaga aacgcaagat ctgcgccaga
    10981 cttgcgatta cgccagcggg attttcccga tgcgcgttat gtccggcgcg aggaatgaca
    11041 tggcagtcgg cagccagttc cgccgccagg gcgcggaatt tgctgtcacg ttcaccacat
    11101 aaataataaa acgcaaatgt gcgggcgcta aggttagcac gtaaatcagg ctggacggcg
    11161 agagaagtcg cctccagcat ggcggcaagg gttgcgccat tattgttgct gcgcagcacc
    11221 accagctccc ggcgttgatc gtcattgagc gaggcaaaaa caggctgttg ataccagtcg
    11281 gcaaataccg ccgttaacgg ttctgtgcaa aaacgctgcg cccattggcg atcggaacgc
    11341 tgacgttccg cacgttgttc agcattttgc agccccggat gcccgccttc gacaataact
    11401 ccacaaagcc ccgccagccc ctggcaagcc gccatcatcg ccacccgtcc gccaagcgag
    11461 taccccacca gccagaagtc aagtatgttg taactaacca aggttttacg cagtaagtcg
    11521 gtgacatcat caaatccatc gacgctaatc gccgccgaac caccatgacc tgggagatca
    11581 acatacaacc gtgagtagtc ggcaaacgcc tcgcccactt cttgccattc gtggcaatcg
    11641 ccggaaaaac cgtgcaaaaa caccagccag ggtaaacctg gttttccgtg ttttgcctgc
    11701 gcgtgcagga tcataaatgg cttacctgcg ccagaagttg ctggagcgtt tgcgcaccat
    11761 cggtgtcgtt aaccaccatt tcaatcaccg tggtggttgg cgtgcgccag gcgtcggcaa
    11821 atgccgtttc aagttcctgc cagttttgcg gacgatgata tttcagctcg aacatcgcgg
    11881 cggcgtgctc aaaatggacg ttttgcggca tcagatagaa acgctcacgc tcgctttgcg
    11941 gcgttggcaa cagcgagaaa atttgcccgc cgttgttgtt caccacaatt aataccagcg
    12001 gcgcagaaac ctgacgcaat aacgccagcg cgttgagatc gtaaagtgcg gagagatcgc
    12061 ccacaatcgc cagcgtcggt ttgccgcttg cccgctgaac gcctgcggcg gtcgaaagca
    12121 gtccgtcgat accgctggcc cctcggttgc tgtacaccgg gtaacctgcc ggaagttgcg
    12181 aaagcgcatc aatcagacgt accaccaggc tgttaccaac aaacaattgc ccctgttcag
    12241 gcagatagtc gcagatgcga tgcgccagtt gcgcttcgcc aaacgcatca cggcgggcaa
    12301 taaccgcctg cattgcctgt tccgccaggc gcgggatttc aacgcaccag ggctggcgtt
    12361 tttctgccgg atgcagctcc agccagtcgg caatattggc aattaagcga cgtccgcgat
    12421 ggtgtgccgg atcaagtcgc ccttcaatgt catcaacaat ccagtactct tctggttcac
    12481 agcttgcctg ccattgcagg agccgtttgc ccgtcaggct gcttcccagt tgcaccacaa
    12541 tttgcgcctg ctgcagctcg ctggtcgctt tggcattgcc taaccaaaga tcggcacacg
    12601 gcagcggctg cccggtttgt gacagcacat cgccaatcag cggccagcca agagtttgcg
    12661 cccacagggc aacttttttg ccctcttccg cactcatgcg cccggcaacc accacgccgc
    12721 gcttttgtcg ccagaagaac cagtcgcgct gtttttcact ttccagacga ggcgcttcac
    12781 gcagccacgg tttgtcgtcc tgccaccagt cacccagacg ctgttgccag ctaagcccgg
    12841 tatcgtccat ttcgccatac agcggttcag caaacgggca gttgatatgg actccccccg
    12901 catgaagcgt accgagagcg tggtcgatgg tagaaaccag ccaacgtgcg gggatatccc
    12961 gggtcgggcg cggcaatgaa atactgtgcg tggggtgaga ggcgaacatt cccggctggc
    13021 gaattgcctg attcgcgccg cagtcaatta gctccggcgg gcgatcggcg gttaacagga
    13081 tcagtttttc tccggttaac ccagcttcaa tcagtgccgg atagagattt gctaccgccg
    13141 tgccggaggt cacaatcacc gccaccggct gcttgctgac tttcgccagc cccagcgcca
    13201 gatgtcccag tccacgctca tcgaaatggg tgtggtgaat gaatgtggaa ttctccgccg
    13261 ccgctaacgt taacggtgta gaacgcgagc caggggcgat acagatgtgt ctgacgccgt
    13321 gacgcgttaa tgcttccaga atgaccgccg cccagcgtcg gttaaatgcg cttactgaca
    13381 tgagtttgtc cggtatcaat attgcggcta agtataagga gctacaaaaa tagattattg
    13441 atatgaatcg gtaatgatgc gactcattac tattccatct gtaataaagt acgcagccct
    13501 gccgctttgt tgtcgatttc ctgccactct tgctcggggt cggaaccacg gacaatgccc
    13561 gcgccagcat ataatcgcac gacattgccg ctaatttttg ctgagcgcag ggaaacgcag
    13621 aattcgcttt gttgtaatga gagatagccc gcagaaccgg cgtaccattc tcgggtgaac
    13681 ggttcgtgac gggcgataaa ctgtcgcgcc agatcgcgcg gtaagccagc aactgctgcc
    13741 gttggctgca actgatgtaa acagatcaca tcatccgctt tgttgagtga agtccagata
    13801 cagcggcgaa gatgctgcac tttacgcaga cgcagtacct gcggcggtaa aacatccagc
    13861 gtctgggtat cggcctgtaa tcgttggcag atatcttcca ccaccagcat gttctcgcgc
    13921 tggtttttat catccgccat cagccactct cctaactgct gcgcctgctt atcatcagga
    13981 ttatttgcta ctgttcccgc cagcgcttca gtacgcagcg ctttgtcacg ccgccgccat
    14041 aaccgttccg gtgaagagcc aagaaaagca ttttcgccat caaaggccat gtaaaaatgg
    14101 tagcaattca gattcagtcg acgactggca gccatcatcg ccgccgcgtt gaccggactt
    14161 gcgaaataca ggtcagttgc ccgagcgagc accactttgt cgagctcacc ttcggcgatg
    14221 gttttcgttg ccagttcgat taattgcgtc cagcccgttt tgtccggcca gtgttgttct
    14281 cgcgtggtgg ttaaatgtaa cccaggcaag ggcttgatac tcaccagtgt ggcgataaat
    14341 tcttttgcct gaatcgcatc gtgctgaagg gagctttcgc tgaatagcgt cagccgcagc
    14401 gtggctttac cgccacagcg tcgccattcc aggcggggta aaagtaaatt gccctgcgac
    14461 gggtcaaaag cattcagccc ccaaatgcgt aagtcggcgt gttccgggtg ctggcgaaga
    14521 aaacgttgtg cctggtccaa cgacgtaaaa cgggtaatcg cgcccaggac ggcagcttct
    14581 tcatcaccat tacgttgttg ccagtagaat tgcgggtacg tttgctgact ggccagccag
    14641 ctcaaggcat caaaagcgtc tttgagaggg aaaggaatat cgataacccg aatgccgggt
    14701 gtcgccggaa tctcttgcga caaatggcgc agtagatttt ccagcgccgt agtaagtgat
    14761 tgcacgcgga cctctccctg ttaaaagcct cacattatac ggggtactac aaaaaaaatg
    14821 cagtaccccg gtgtagggag gttttaacgg cgtgccagca acagtcctag taccagccca
    14881 acggccgcgc ccacaccaat tccttgccag ggtttttcgt ggacgtagtc atcagcacga
    14941 taaactgcct gcttcgcccg atagtaataa ctgtctgaag cctggctaac ccgttttttc
    15001 acatcatcca gcgctttttc tgcacgcgct ttcagctcaa catatttctg atcggcggga
    15061 tcgccagagg agcggagcac ctcttccagt gtttcactaa gcagcgtcag gtcgtcatcg
    15121 atacgtgtat caccaaactg attagacatt ctcgttctcc atttgcgtaa aacctgtcac
    15181 taactataga caagggttgt tgattacgcc tgaattacct cgcgtgccat cccaatgtgt
    15241 gggataccat cttcttcata gacctccgtc acagggataa aaccgaaact ctggtagaag
    15301 ttttgcagat gcgcctgcgc cccgaggtaa acaggcttat caggccagtg atgcgtacat
    15361 gtttcgagtg ttttactcat cagctgctgc cccacttttt cgccacgcaa cgcttcactg
    15421 acaatcaccc gacctataac gaccggctca agatcatcat cacttttcag aatcctcgca
    15481 tatgccacca gttcatcatt tttccaaccg agaatatggc gattatcccc cgtcaaatca
    15541 tcaccatcga tatcctgata agggcaattc tgctcgacaa caaacaccgc gcaacgcagt
    15601 tgtaataagg cataaagctg ggaaaccgat aatttagagt gatgcagatc ttgccattca
    15661 atcataatgc tctcctttta gatgtatgcc ttatactagc cggaatattt tttgaaacgt
    15721 gatgaactca tggaattaat ttttttaggt acttcggccg gtgtgccaac ccgcacgcgc
    15781 aatgtcacgg caatattgct taacctgcaa catccgaccc agagcggtct ttggttgttt
    15841 gactgcggtg aaggcaccca gcatcagcta ctgcatacag cctttaaccc tggaaaactg
    15901 gacaagattt ttatcagtca ccttcatggc gatcatcttt ttggtttacc cggcttgctg
    15961 tgcagtcgtt ctatgtcagg cattatccaa cccttaacga tttatggtcc gcaaggtatc
    16021 cgtgaatttg tggaaaccgc gctgcggatt agcggctcat ggaccgatta tccgctggaa
    16081 attgtcgaaa ttggcgctgg cgaaattctc gatgatggcc tgcgcaaagt aaccgcttat
    16141 ccgctggaac acccactgga atgttatggc tatcgtattg aagaacatga taaaccgggt
    16201 gcattaaatg cccaggcatt aaaagctgct ggcgtgccgc ctggtccact gtttcaggaa
    16261 ttaaaagcgg gcaaaacaat cacgctggaa gatggaaggc agattaacgg cgcagattac
    16321 ttagctgctc cagtgccagg taaagcgctc gctattttcg gcgataccgg cccctgcgat
    16381 gccgcacttg acctggctaa aggtgtcgat gtcatggtgc acgaagcgac gctggatata
    16441 accatggaag ccaaagccaa tagtcgcggc catagctcta cacgccaggc tgcgacacta
    16501 gcccgtgagg ctggagtcgg taagctaatc attacccacg tcagctcgcg ctatgatgac
    16561 aaaggttgtc agcacctgtt acgtgaatgc aggtcaattt tcccggcgac tgaactagcg
    16621 aatgatttca ccgtgtttaa cgtttaactc tgcttattat taaaaacagg gcgaaacttg
    16681 ccctgttatc gcaacccgcg ctacatatat ccacccacac gggcatattg agcgattttt
    16741 gatatttatt catctcctta cgcactatat tcagagcaat aagttgcctc tttttatctt
    16801 cattcagcac aacctttgca actaaaagga gcccatgatg gttacagttg tcagcaatta
    16861 ttgtcaatta tctcaaaccc aactcagtca gacatttgca gaaaaattta ctgtgaccga
    16921 ggaattactg cagtctttaa aaaaaacagc gttatccgga gatgaagaaa gtattgagtt
    16981 actgcataat attgcgttag gttatgatga atttggaaaa aaagctgaag atattcttta
    17041 ccatattgtt agaaacccaa caaatgagac cctatcgatt atccgactta ttaaaaatgc
    17101 ctgtttaaaa ttatataatt tggcacatac cgcaaccaac tcccacctta aaccaactgg
    17161 tccggatact tcagatgttc tcctgttcaa aaagctattc tccccttcga aattaatgac
    17221 aattatcggt gatgaaattc ctcttatatc tgaaaaacag tcgctttcaa aggtgctttt
    17281 aaatgatgag aataatgaac tgagtgatga tacaaacttc tgggataaaa atcgtcaatt
    17341 aaccacagat gaaatagctt gctatcttca gaagatcgcc gctaatgcaa aaaatactca
    17401 agtcaattat cctactggtc tctacgtccc ctactccacc agaactcacc tggaagacgc
    17461 tctcaatgaa aatattaaga gcgatccatc atggccgaat gaagtccagt tattccccat
    17521 aaatactggc ggacactgga tattagtttc gctacagaaa atagtaaata aaaaaaataa
    17581 taaactacaa
//
LOCUS       DAPOAV010000088        17420 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.088, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000088 DAPOAV010000000
VERSION     DAPOAV010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17420
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.088"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(323..1324)
                     /locus_tag="RN951_003496"
     CDS             complement(323..1324)
                     /locus_tag="RN951_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000100290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDX2528446.1"
                     /translation="MSSWLAMLQDAAEMFVFLAVELSLLFIVISAGVSLIRQKVPDHK
                     IQQMMGARKGRGYLLAALLGAVTPFCSCSTIPMLRGLLSAKAGFGPTLTFLFVSPLLN
                     PIIVGLMWMTFGWKVTLLYAIIAAGVSVLASIILDSLGFERHIIASKSSSANCCALAK
                     TSPGTTYTPIKVSCCSPAAKAIENPVVTCCSTKAVVSINPIKLATKDALQQFKDVLPY
                     LLLGVLIGSFIYGFIPSAWIAAHAGADNPFAIPLSAVVGIPLYIRAEAVIPLASVLMT
                     KGMGLGALMALIIGSAGASLTEVILLKSMFRMPMIAAFLTVILGMAILMGYLTQLLF"
     gene            1432..1728
                     /locus_tag="RN951_003497"
     CDS             1432..1728
                     /locus_tag="RN951_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001465662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX2528447.1"
                     /translation="MQLEEVAKALKELGHPTRLFIFKHLVKAGEQGLPVGELQKQLGI
                     PGSTLSHHISALVSVGLVKQNRESRTLMCVSQYAMLEAIIEFLREECCVNSKIA"
     gene            complement(1851..2276)
                     /gene="arsC"
                     /locus_tag="RN951_003498"
     CDS             complement(1851..2276)
                     /gene="arsC"
                     /locus_tag="RN951_003498"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-dependent arsenate reductase"
                     /protein_id="HDX2528448.1"
                     /translation="MSNITIYHNPACGTSRNTLEMILNSGTEPTIIYYLETPPTRDEL
                     VKLIADMGISVRALLRKNVEPYEELGLAEDKFTDDRLIDFMLQHPILINRPIVVTPLG
                     TRLCRPSEVVLEILPDAQKGAFSKEDGEKVVDEAGKRLK"
     gene            complement(2289..3578)
                     /gene="arsB"
                     /locus_tag="RN951_003499"
     CDS             complement(2289..3578)
                     /gene="arsB"
                     /locus_tag="RN951_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenite/antimonite:H(+) antiporter ArsB"
                     /protein_id="HDX2528449.1"
                     /translation="MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPG
                     DIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRWGNGRGRLLFTWIVLLG
                     AAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLV
                     NIVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAI
                     KDPATFKTGWVVLLLLLVGFFVLEPLGIPVSAIAAVGALILFVVAKRGHAINTGKVLR
                     GAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAATLGTGFLTAFLSSI
                     MNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQ
                     KNMTISWGYYFRTGIIMTLPVLFVTLAALALRLSFTL"
     gene            complement(3632..3985)
                     /gene="arsR"
                     /locus_tag="RN951_003500"
     CDS             complement(3632..3985)
                     /gene="arsR"
                     /locus_tag="RN951_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="As(III)-sensing metalloregulatory
                     transcriptional repressor ArsR"
                     /protein_id="HDX2528450.1"
                     /translation="MSFLLPIQLFKILADETRLGIVLLLSELGELCVCDLCTALDQSQ
                     PKISRHLALLRESGLLLDRKQGKWVHYRLSPHIPAWAAKIIDEAWRCEQEKVQAIVRN
                     LARQNCSGDSKNICS"
     gene            4494..4577
                     /locus_tag="RN951_003501"
     CDS             4494..4577
                     /locus_tag="RN951_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165328.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Damage inducible protein"
                     /protein_id="HDX2528451.1"
                     /translation="MIDKAIIVLGALIALLELIRFLLQLLN"
     gene            complement(4631..5983)
                     /gene="gorA"
                     /locus_tag="RN951_003502"
     CDS             complement(4631..5983)
                     /gene="gorA"
                     /locus_tag="RN951_003502"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003861215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HDX2528452.1"
                     /translation="MTKHYDYIAIGGGSGGIASINRAAMYGQKCALIEAKELGGTCVN
                     VGCVPKKVMWHAAQIREAIHMYGPDYGFDTTINKFNWETLIASRTAYIDRIHTSYENV
                     LGKNNVDVIKGFARFVDAKTLEVNGETITADHILIATGGRPSHPDIPGVEYGIDSDGF
                     FALPALPERVAVVGAGYIAVELAGVINGLGAKTHLFVRKHAPLRSFDPMISETLVEVM
                     NAEGPQLHTNAIPKAVVKNADGSLTLELEDGRSETVDCLIWAIGREPANDNINLEAAG
                     VKTNEKGYIVVDKYQNTNIEGIYAVGDNTGAVELTPVAVAAGRRLSERLFNNKPDEHL
                     DYSNIPTVVFSHPPIGTVGLTEPQAREQYGDDQVKVYKSSFTAMYTAVTTHRQPCRMK
                     LVCVGSEEKIVGIHGIGFGMDEMLQGFAVALKMGATKKDFDNTVAIHPTAAEEFVTMR
                     "
     gene            complement(6055..6897)
                     /gene="rlmJ"
                     /locus_tag="RN951_003503"
     CDS             complement(6055..6897)
                     /gene="rlmJ"
                     /locus_tag="RN951_003503"
                     /EC_number="2.1.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2030)-N(6))-methyltransferase"
                     /protein_id="HDX2528453.1"
                     /translation="MLSYRHSFHAGNHADVLKHTVQSLIIESLKEKDKPFLYLDTHAG
                     AGRYQLGSEHAERTGEYLEGIARIWQQDDLPAELEAYINVVKHFNRSGQLRYYPGSPL
                     IARQLLREQDSLQLTELHPSDYPLLRSEFQKDSRARVEKADGFQQLKAKLPPVSRRGL
                     ILIDPPYEMKTDYQAVVSGIAEGYKRFATGTYALWYPVVLRQQIKRMIHDLEATGIRK
                     ILQIELAVLPDSDRRGMTASGMIVINPPWKLEQQMNNVLPWLHSKLVPAGTGHATVSW
                     IVPE"
     gene            7100..9142
                     /gene="prlC"
                     /locus_tag="RN951_003504"
     CDS             7100..9142
                     /gene="prlC"
                     /locus_tag="RN951_003504"
                     /EC_number="3.4.24.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020317218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase A"
                     /protein_id="HDX2528454.1"
                     /translation="MTNPLLTPFELPPFSKILPEHVVPAVTKALNDCRENVERVVAQG
                     APYTWENLCQPLAEVDDVLGRIFSPVSHLNSVKNSPELREAYEQTLPLLSEYSTWVGQ
                     HEGLYKAYRDLRDGDHYATLNTAQKKAVDNALRDFELSGIGLPIEKQQRYGEIATRLS
                     ELGNQYSNNVLDATMGWTKLVTDEAELAGMPESALAAAKAQAEAKELEGYLLTLDIPS
                     YLPVMTYCDNQALREEMYRAYSTRASDQGPNAGKWDNSKVMEEILALRHELAQLLGFE
                     NYAFKSLATKMAENPQQVLDFLTDLAKRARPQGEKELAQLRAFAKAEFGVDELQPWDI
                     AYYSEKQKQHLYSISDEQLRPYFPENKAVNGLFEVVKRIYGITAKERKDVDVWHPDVR
                     FFELYDENNELRGSFYLDLYARENKRGGAWMDDCVGQMRKADGSLQKPVAYLTCNFNR
                     PVNGKPALFTHDEVITLFHEFGHGLHHMLTRIETAGVSGISGVPWDAVELPSQFMENW
                     CWEPEALAFISGHYETGEPLPKELLDKMLAAKNYQAALFILRQLEFGLFDFRLHAEFR
                     PDQGAKILETLAEIKKLVAVVPSPSWGRFPHAFSHIFAGGYAAGYYSYLWADVLAADA
                     FSRFEEEGIFNRETGQSFLDNILSRGGSEEPMDLFKRFRGREPQLDAMLEHYGIKG"
     gene            9150..9902
                     /gene="rsmJ"
                     /locus_tag="RN951_003505"
     CDS             9150..9902
                     /gene="rsmJ"
                     /locus_tag="RN951_003505"
                     /EC_number="2.1.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1516)-N(2))-methyltransferase
                     RsmJ"
                     /protein_id="HDX2528455.1"
                     /translation="MKICLIDETGTGDGALSVLAVRWGLEHDEDNLMALVLTPEHLEL
                     RKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRD
                     AFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTD
                     ITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVK
                     RPDYAPPLANVATPNAVVTKGHRFDIYAGTPV"
     gene            complement(9951..11420)
                     /gene="dtpB"
                     /locus_tag="RN951_003506"
     CDS             complement(9951..11420)
                     /gene="dtpB"
                     /locus_tag="RN951_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpB"
                     /protein_id="HDX2528456.1"
                     /translation="MNTTTPMGMLQQPRPFFMIFFVELWERFGYYGVQGVLAVFFVKQ
                     LGFSQEQAFVTFGAFAALVYGLISIGGYVGDHLLGTKRTIVLGALVLAIGYFMTGMSL
                     LKPDLIFIALGTIAVGNGLFKANPASLLSKCYPPKDPRLDGAFTLFYMSINIGSLIAL
                     SLAPVIADRFGYSVTYNLCGAGLIIALLVYIACRGMVKDIGSEPDFKPMSFSKLLYVL
                     LGSVVMIFVCAWLMHNVEVANLVLIVLSIVVTIIFFRQAFKLDKTGRNKMFVAFVLML
                     EAVVFYILYAQMPTSLNFFAINNVHHEILGFSINPVSFQALNPFWVVLASPILAGIYT
                     HLGNKGKDLSMPMKFTLGMFMCSLGFLTAAAAGMWFADAQGLTSPWFIVLVYLFQSLG
                     ELFISALGLAMIAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPDNITDPLET
                     LPVYTNVFGKIGLVTLGVAVVMLLMVPWLKRMIATPESH"
     gene            complement(11738..12172)
                     /gene="uspA"
                     /locus_tag="RN951_003507"
     CDS             complement(11738..12172)
                     /gene="uspA"
                     /locus_tag="RN951_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspA"
                     /protein_id="HDX2528457.1"
                     /translation="MAYKHILIAVDLSPESKVLVEKAVSMARPYNAKVSLIHVDVNYS
                     DLYTGLIDVNLGDMQKRISEETHHALTELSTNAGYPITETLSGSGDLGQVLVDAIKKY
                     DMDLVVCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDEEE"
     gene            12563..12898
                     /gene="uspB"
                     /locus_tag="RN951_003508"
     CDS             12563..12898
                     /gene="uspB"
                     /locus_tag="RN951_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspB"
                     /protein_id="HDX2528458.1"
                     /translation="MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYV
                     DGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVV
                     SLIALMIWH"
     gene            complement(12969..14468)
                     /gene="pitA"
                     /locus_tag="RN951_003509"
     CDS             complement(12969..14468)
                     /gene="pitA"
                     /locus_tag="RN951_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter PitA"
                     /protein_id="HDX2528459.1"
                     /translation="MLHLFAGLDLHTGLLLLLALAFVLFYEAINGFHDTANAVATVIY
                     TRAMRSQLAVVMAAVFNFLGVLLGGLSVAYAIVHMLPTDLLLNMGSSHGLAMVFSMLL
                     AAIIWNLGTWYFGLPASSSHTLIGAIIGIGLTNALMTGTSVVDALNIPKVLSIFGSLI
                     VSPIVGLVFAGGLIFLLRRYWSGTKKRARIHLTPAEREKKDGKKKPPFWTRIALILSA
                     IGVAFSHGANDGQKGIGLVMLVLIGVAPAGFVVNMNATGYEITRTRDAINNVEAYFEQ
                     HPALLKQATGADQLVPAPEAGATQPAEFHCHPSNTINALNRLKGMLTTDVESYDKLSL
                     DQRSQMRRIMLCVSDTIDKVVKMPGVSADDQRLLKKLKSDMLSTIEYAPVWIIMAVAL
                     ALGIGTMIGWRRVATTIGEKIGKKGMTYAQGMSAQMTAAVSIGLASYTGMPVSTTHVL
                     SSSVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAVLLSGGLYWLSLQFL"
     gene            14700..15902
                     /locus_tag="RN951_003510"
     CDS             14700..15902
                     /locus_tag="RN951_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDX2528460.1"
                     /translation="MERFDAIIIGAGAAGIFCSALAGQAGRRVLLIDNGKKPGRKILM
                     SGGGRCNFTNLYVEPGAYLSQNPHFCKSALARFTQWDFIDLVNKHGIAWHEKTLGQLF
                     CDDSAQQIVDMLVDECEKGNVTFRLRSEVLSVAKDETGFTLELNGMTVGCEKLVIATG
                     GLSMPGLGASPFGYKIAEQFGLNVLPTRAGLVPFTLHKPLLEELQVLAGVAVPSVITA
                     ENGIVFRENLLFTHRGLSGPAVLQISSYWQPGEFVSINLLPDVDLETFLNEQRNAHPN
                     QSLKNTLAVHLPKRLVERLQQLGQIPDVSLKQLNVRDQQALISTLTDWRVQPNGTEGY
                     RTAEVTLGGVDTNELSSRTMEARKVPGLYFIGEVMDVTGWLGGYNFQWAWSSAWACAQ
                     DLIAAKSS"
     gene            complement(16218..17270)
                     /locus_tag="RN951_003511"
     CDS             complement(16218..17270)
                     /locus_tag="RN951_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2776 domain-containing protein"
                     /protein_id="HDX2528461.1"
                     /translation="MNIYIGWLFKLIPLIMGLICIALGGFVLESSGQSEYFVAGHVLI
                     SLAAICLALFTTAFIIISQLTRGVNTFYNTLFPIIGYAGSIITMIWGWALLAGNDVMA
                     DEFVAGHVIFGVGMIAACVSTVAASSGHFLLIPKNAAGSKSDGTPVQAYSSLIGNCLI
                     AVPVLLTLLGFIWSITLLRSADITPHYVAGHVLLGLTAICACLIGLVATIVHQTRNTF
                     STKEHWLWCYWVIFLGSITVLQGIYVLVSSDASARLAPGIILICLGMICYSIFSKVWL
                     LALVWRRTCSLANRIPMIPVFTCLFCLFLASFLAEMAQTDMGYFIPSRVLVGLGAVCF
                     TLFSIVSILEAGSAKK"
BASE COUNT         4546 a         4380 c         4477 g         4017 t
ORIGIN      
        1 agtaatattt ttgtgatgtt ttagatgtgt aataatgaac caggttaaag tgtatttaaa
       61 aatgtgttgt attagcgact gaaatctgcc ttttaaaaag gaggagggta ctgagacaaa
      121 gagtcattgc ttctccgata aaatgtcaga gaagcatgat tacgtggtta ttgtctgttg
      181 atgacttgtt gaccgagccg tcatcattct caatgcatta gttaaatcat ttgtgatttt
      241 taaggattat cctgtctatg attttctatt tagaaggata tggcactaac tatgcatctt
      301 atagtttact gctggcatct atttaaaata gcaattgagt caaatagccc atcaagatag
      361 ccatacctaa tataaccgtc aggaatgcag ctatcatcgg cattctgaac attgatttaa
      421 gtaatatcac ttccgtcagg cttgcgccgg cactgccgat gattaatgcc attaatgctc
      481 ccagacccat tccttttgtc atcagaacag atgccagagg gataactgcc tcagcccgga
      541 tatacagcgg aataccgaca acggcgctta atgggatggc gaagggatta tctgctcctg
      601 catgagcggc aatccacgct gagggaataa agccataaat aaaagatcct attaatactc
      661 ctaacaaaag atatggcagt acatctttaa actgttgcaa cgcatctttg gtggctagtt
      721 ttatgggatt aatacttact acagctttgg tactgcaaca ggtaactacg gggttctcaa
      781 tggctttagc cgctggacta caacaactca cttttatggg cgtatatgtc gttcccggcg
      841 aagtttttgc tagagcacaa caatttgctg atgagctttt actggcaatg atatgacgtt
      901 caaaccccag agaatccagg ataatactgg caagaacgga gacgccggcg gcgataatcg
      961 cgtacaacaa ggtgactttc caaccaaagg tcatccacat tagtccgacg ataatgggat
     1021 taagtaatgg tgaaacaaat aaaaaagtga gagtcggacc aaacccggct ttcgctgaca
     1081 acaatccacg taacatgggt attgtcgagc aactacagaa cggggtaacg gctcccaaca
     1141 gagcagccag gagatagcct ctcccttttc tggcccccat catctgctgg attttatggt
     1201 ctggcacctt ttgtcttatc aggctgacac cggcactaat cactataaac agcaacgaaa
     1261 gctcgacggc gagaaacaca aacatctctg cggcatcttg cagcatcgca agccaactac
     1321 tcatacgtaa cctcattgga taaatctata tttccagaat aatcgaaatg aaattcagat
     1381 caagatattt ctggtattat cgaaatatca accagacaaa gggggtgtca tatgcagttg
     1441 gaagaagttg ctaaagcgct gaaagagcta ggtcacccga cccgtttgtt catattcaaa
     1501 cacctggtca aagcggggga gcaaggtttg ccggtcggtg agttgcaaaa gcagcttggg
     1561 atacccggct ctacactcag tcaccatatt tcagcactgg tatcggtagg gctggttaaa
     1621 caaaaccgtg agagtcggac gctgatgtgt gtttcgcaat acgcaatgct ggaagcgata
     1681 attgaattct tacgcgagga gtgctgcgta aatagcaaaa ttgcctgatg cgctacgcgc
     1741 tacagatttc atgccatgca cggttttgta ggtcggataa gacgcgttag cgtcgcatcc
     1801 gacataaaca aagcgcactt taccaactat gggcagtgga tatcgccgct ttatttcaac
     1861 cgcttacccg cttcatcaac cactttctcg ccatcttcct tggagaatgc gcctttttgc
     1921 gcatctggca gaatttccag caccacttct gaagggcggc acaggcgagt tcccagcggc
     1981 gtcaccacaa tcgggcgatt aatcagaatc gggtgctgaa gcataaagtc gattaaccga
     2041 tcgtcagtaa atttatcttc tgcaaggccc agttcctcat acggctcgac gtttttacgc
     2101 aacagcgcgc gtacggaaat ccccatatcg gcaatgagtt tgaccagctc atcgcgcgtt
     2161 ggcggtgttt ccagataata gataatggtc ggttctgtac cgctgttgag gatcatctcc
     2221 agcgtattac gcgacgtacc gcaggccggg ttgtgataaa tggtaatgtt gctcatatca
     2281 atatctcatt acaaagtgaa agagagacgt agcgccagcg cagccagcgt cacaaaaagc
     2341 accggcaggg tcatgataat ccctgtacgg aagtaatatc cccagctgat agtcatattc
     2401 ttctgcgaaa gtacgtgcag ccagagtagc gtagccaggc taccaattgg ggtaattttc
     2461 ggtcccaaat cgcagccaat cacattggca taaaccatcg cttctttgat aacgccagat
     2521 gccgtgctgc catcaatgga caacgcgcca accagtaccg tcggcatatt gttcataata
     2581 gaagagagga aggcggtgag gaatccggtg ccgagcgtcg cggcccacag gccgttatcc
     2641 gccagcacgt tgagtacgcc agaaagatat tccgttaatc cggcattgcg caggccataa
     2701 accaccagat acatgccgag cgagaagatg acaatctgcc agggggcacc gcgcaggact
     2761 ttacccgtat taatcgcatg accgcgttta gcgacgacaa ataatatcag cgcgcccaca
     2821 gctgcaatgg cgctcaccgg aatgccgagc ggttccagga cgaaaaatcc caccagcaga
     2881 agcagtaaaa caacccagcc agttttgaac gtagcaggat ctttgatcgc ttctgcggga
     2941 gatttcagca gcgccatatc gtagttctgc ggaatatctt tgcgaaaata gagatgtaac
     3001 atcaccagcg tggcaacaat cgcggcgata tccaccggca ccatcaccga ggcgtattcg
     3061 cgaaagccga ggccaaagaa atcagcggaa acgatattca ccaggttgga gacaataagc
     3121 ggcaggctgg cggtatcggc aatgaatccg gccgccatca cgaacgccag cgtagtgcct
     3181 ttactgaacc ctaaagccag cagcatggcg atgacaatcg gtgtcaaaat aagcgccgcg
     3241 ccatcattgg caaacagggc ggcaacggca gcaccgagca ggacaatcca ggtaaacagc
     3301 aagcgaccac gaccattacc ccagcgtgag acgtgcagcg ccgcccattc aaaaaagccg
     3361 gactcatcca gcagcaggct gatgataatg acggcgataa acgcagccgt cgcgttccag
     3421 acgatattcc acaccaccgg aatatcaccc ggatggacca cgcccgtaac taacgccagt
     3481 actgcgccga gcgttgcact ccagccgatg cctaaacctt tcggctgcca gataaccaat
     3541 acgatggtca ggacaaagat agcgcctgcc agtaacataa tgcctcccgg ataaaacaca
     3601 tctgaaaatt catatgtgtt tagctaaatt tttaactgca aatgttctta ctgtccccgg
     3661 aacagttttg tcgagccagg ttgcggacaa tcgcctgaac cttttcctgt tcacatcgcc
     3721 aggcctcatc aataattttc gccgcccatg ctggaatatg cggtgataag cggtaatgaa
     3781 cccacttacc ttgcttgcgg tccagcaata gcccgctttc acgcagcaat gccaggtggc
     3841 gggagatctt gggctgcgac tggtcgagag cagtgcagag atcgcagacg cataactctc
     3901 ccagttcgct gagcagtaaa acgatgccca gacgggtttc atcagcaaga attttgaaca
     3961 attggatggg taaaagaaat gacatattgc gctcctgatt gttgcaggta gtgtctctct
     4021 tcgaagcgga taagtcaaaa acatatatga cttaacgaat gtgtaagtgc agaggaaggt
     4081 aataggtgtg aattttgagt tggctattca tttgaaagga ggtctgaatc aggacgtaaa
     4141 aaaaccgact ttgcgtcggt tttttacttt ccagccctga gttggtggca ctggctggag
     4201 tgagaatgcc attatctaac gcatcaatgc taataccata ctgaaactat tgcaaggaca
     4261 tgctggtttt ataacctgaa tgtactgtat gattatccag ttagctctga ggcattttca
     4321 ctctggtaat gcgcataaac gctttcaaag tcctggtcag aagtacgggt ggtgccgtta
     4381 actgatgctc tggccggagt gagaatgcca ttatctaaca atagggcatg cgccgtgaca
     4441 ggcagtggat gagtaagcgg atgcattctc actccatcgc atggagaaaa cgggtgattg
     4501 ataaagcaat catcgttctt ggggcgttaa ttgcgctgct ggaactgatc cgctttctgc
     4561 ttcagcttct gaactgatag cggaaacgta attaagggct aagagcacac tactcttagc
     4621 cctttaacat ttaacgcatt gtcacgaact cttctgccgc cgttgggtga atggcgacgg
     4681 tattgtcgaa gtcttttttg gttgcaccca tcttcagcgc caccgcgaag ccctgcaaca
     4741 tttcgtccat accaaagcca atgccgtgaa taccgacaat cttctcttcc gatccaacgc
     4801 acaccagctt catgcggcac ggctggcggt gagtggtgac ggcggtatac atcgcggtga
     4861 aagaggattt atacactttc acctgatcgt cgccatactg ctcgcgcgcc tgcggttccg
     4921 ttaaaccaac agtaccaatc ggcggatggc tgaagaccac ggtcggaatg ttgctgtaat
     4981 ccagatgctc atccggcttg ttattaaaca ggcgttcaga gagacggcga cccgctgcaa
     5041 ctgccaccgg tgtcagctcc actgcacccg tgttatcgcc caccgcgtaa ataccttcaa
     5101 tattggtgtt ttgatattta tcgacgacga tatagccttt ttcgttagtt ttaacgccag
     5161 cggcttccag gttgatgttg tcattggcag gctcgcgacc aatcgcccaa atcaggcaat
     5221 ccaccgtttc actgcgacca tcttccagct ccagcgtcag gctaccatcg gcatttttca
     5281 ctaccgcttt cgggatggcg ttggtgtgca gctgcgggcc ttcggcgttc atcacttcga
     5341 ccagcgtttc ggaaatcatc gggtcgaagc tgcgcagcgg cgcatgttta cgcacaaaca
     5401 gatgcgtttt cgcgccgagg ccgttaatca cgcccgccag ctcaacggcg atgtaacccg
     5461 cgccaacaac cgccacgcgc tctggcaaag caggaagggc gaagaagcca tcagaatcaa
     5521 taccgtattc cacgcccgga atatccgggt ggctcggacg accgcctgtg gcgatcagaa
     5581 tatgatcggc cgtgatggtt tcgccgttta cctccagcgt tttggcatca acgaagcggg
     5641 caaagccttt gattacatca acgttatttt taccgagcac gttttcatag gaagtatgaa
     5701 tacggtcgat ataggcggta cggctggcga tcaacgtttc ccagttgaat ttattgatag
     5761 tggtatcaaa accataatcc gggccgtaca tatggatcgc ttcacggatt tgcgccgcgt
     5821 gccacatcac ttttttcggc acacagccaa catttacgca ggtgccgccc agctctttgg
     5881 cttcaatcag cgcacatttc tggccgtaca tagccgcgcg gttgatggag gcgataccgc
     5941 cgctgccgcc gccgatggcg atgtaatcat agtgtttagt catgacaaag tgtccttatc
     6001 gttgattacc gcgattgtag cgcgagacgt aataggtgcc agcaatggct gcaattactc
     6061 cggcacgatc cagcttacgg tggcgtgccc ggtgcctgcc ggaaccagtt tgctgtgcag
     6121 ccacggcagc acgttattca tctgctgttc cagtttccac ggcgggttaa tcacaatcat
     6181 gccggaagcg gtcatgccac ggcgatcgct gtctggcagt accgccagtt caatttgcag
     6241 aattttgcga ataccggtcg cttccagatc gtggatcatg cgcttaattt gctgacgcag
     6301 caccaccgga taccacagtg cgtaagtacc agtggcgaaa cgtttgtaac cttctgctat
     6361 cccgctgacc accgcctgat agtcggtttt catttcatac ggcgggtcga taaggattaa
     6421 accacggcgg gaaaccggcg gcagtttggc cttaagctgc tggaaaccat cggctttttc
     6481 gacgcgcgca cggctgtctt tctgaaattc agaacgcagc aacgggtaat cgctcgggtg
     6541 cagttcggtc agttgcaggc tgtcttgttc gcgcagtagc tggcgagcaa tcaatggcga
     6601 accggggtag taacgcaact gaccgctacg gttgaagtgt tttaccacat tgatgtacgc
     6661 ctccagttct gcgggcaaat cgtcctgctg ccagatacgg gcgatgcctt cgagatattc
     6721 gccggtacgc tcggcatgtt cgctgcctaa ctgataacgc ccggcccctg cgtgggtgtc
     6781 gagatagaga aacggtttat ctttctcttt cagcgactcg atgatcaggc tctgaacggt
     6841 atgtttaagg acgtcggcgt ggttgccagc gtgaaagctg tggcgataac tgagcatggg
     6901 taaaggtgtt ccggtaagta aaaatcggcc cgtattcggg gcgcacaaaa gcgtatcagg
     6961 acagtatacc gaaaagaggc cgccgccgcg aaagcgtaac gtttctcatt gaaattcact
     7021 acacttaacc ccatgctaca cacattatgt aaagcgcctg ttgagcgctt ccttaacctc
     7081 tttaaccagg actgcgcgaa tgacgaatcc gttactgact ccctttgaat tgcctccgtt
     7141 ttctaaaatt ctcccggaac atgtcgttcc agccgtgact aaggcgctga acgactgccg
     7201 cgaaaatgtg gagcgcgtag tagcgcaagg agcaccgtac acctgggaaa atctctgcca
     7261 gccgttggcg gaagtggacg atgtgctggg gcgtatcttc tccccggtca gccacctgaa
     7321 ctcggtgaaa aatagcccgg aactgcgtga agcgtacgaa caaaccctgc cgctgctgtc
     7381 ggaatacagc acctgggtag ggcaacatga agggctgtat aaagcgtatc gcgacctgcg
     7441 cgatggcgat cattacgcca cgctgaacac ggctcagaaa aaagcggttg ataacgcact
     7501 gcgcgacttc gaactctctg gcatcggtct gccaatagag aaacaacaac gctacggtga
     7561 gattgccact cgtctttccg agctgggcaa ccagtacagc aacaacgtcc tcgatgcgac
     7621 gatgggctgg accaaactcg ttaccgacga agcggagctg gcggggatgc ctgaaagcgc
     7681 gctggctgcg gcaaaagccc aggccgaagc gaaagagctg gaaggctacc tgctgacgct
     7741 ggatatccca agctacctgc cggtaatgac ctactgcgac aaccaggcct tgcgtgaaga
     7801 gatgtatcgc gcttacagca cccgcgcctc cgatcaaggc ccgaacgccg gtaaatggga
     7861 taacagcaag gtgatggaag agatcctcgc tctgcgtcac gaactggcgc aactgctggg
     7921 ctttgaaaac tacgccttta aatcccttgc cactaaaatg gcagaaaacc cgcagcaggt
     7981 gctggatttc ttaaccgatc tggcaaaacg cgcgcgtccg caaggcgaaa aagagctggc
     8041 acaactgcgc gccttcgcca aagcggaatt tggcgtcgat gagttgcagc cgtgggatat
     8101 cgcgtactac agcgaaaaac aaaaacagca cctctacagc atcagcgacg agcagctgcg
     8161 tccgtacttc ccagaaaaca aagcggttaa cggcctgttt gaagtggtga aacgtattta
     8221 cggcatcacc gctaaagagc gtaaagatgt tgatgtctgg catccggatg tacgtttctt
     8281 cgaactgtat gacgaaaata acgaactgcg cggcagcttc tacctcgatc tgtatgcccg
     8341 tgaaaacaag cgcggcgggg cgtggatgga tgactgcgta ggccagatgc gtaaagctga
     8401 tggttctctg caaaaaccgg tcgcgtattt gacttgtaac ttcaaccgcc cggtaaatgg
     8461 taaaccggcg ctgttcactc acgacgaagt gatcaccctg ttccacgagt tcggtcacgg
     8521 cctgcaccat atgctgaccc gcatcgaaac cgctggtgtt tccggtatca gcggtgtgcc
     8581 gtgggatgcg gtcgaactgc cgagtcagtt tatggaaaac tggtgctggg agccggaggc
     8641 gctggcgttt atctccggtc actacgaaac cggcgaaccg ctgccgaaag agttgctgga
     8701 taaaatgctg gcggcgaaga actaccaggc ggcgctgttt attctgcgcc agctggagtt
     8761 cggcctgttc gatttccgcc tccatgccga gttccgcccg gatcagggag cgaaaatcct
     8821 cgaaactctg gcagaaatca agaaactggt tgccgtagta ccgtctccat cctggggccg
     8881 tttcccgcac gctttcagcc atattttcgc tggtggttat gccgcaggtt actacagcta
     8941 cctgtgggct gacgtactgg cggcagatgc tttctcgcgc tttgaggaag agggcatttt
     9001 caaccgtgaa accgggcagt cgttcctcga caacattctg agccgtggcg gttcagaaga
     9061 gccgatggat ctgttcaaac gcttccgtgg tcgtgaaccg cagctggatg cgatgctgga
     9121 gcattacggc attaagggct gatcattcag tgaaaatctg cttaattgat gaaacaggca
     9181 ccggagacgg tgccttatct gttctggcgg tccgctgggg gctggagcac gatgaagaca
     9241 acctgatggc gctggtgtta acgccggaac atctggaatt gcgcaagcgt gatgagccaa
     9301 aacttggcgg catctttgtt gattttgttg gcggagcgat ggcgcaccga cgcaaattcg
     9361 gcggtggtcg cggtgaggcg gtggcgaaag cggtgggcat taaaggcgat tatttgccgg
     9421 atgtggtgga tgccaccgca gggctggggc gcgatgcctt tgtgctggct tcagtcggct
     9481 gccgcgtgcg gatgctggag cgtaatccag tcgttgccgc attgctcgac gacggcctgg
     9541 cgcgtggtta tgcggatgcg gaaatcggcg gctggttgca ggagcggttg cagttaattc
     9601 acgcctccag cctgacggcg ctgactgata ttaccccgcg cccgcaggtg gtttatctcg
     9661 acccgatgtt cccgcataag cagaaaagcg cgctagtgaa aaaagagatg cgtgtctttc
     9721 agtcgctggt gggaccggat cttgatgccg atggattact ggagcctgca cgcttgctgg
     9781 cgaccaaacg cgtggtggta aagcgcccgg actacgcgcc accgctggcg aatgtcgcca
     9841 cgccaaacgc ggtagtcact aaagggcata ggtttgatat ttatgcaggt acgccagtgt
     9901 aaaagtaaac cagggtagcg ataacgctac cctgctttct gcaagaataa ttaatggctt
     9961 tccggcgtcg caatcatgcg tttcagccac ggcaccatca acagcatcac tactgcaacg
    10021 cccagtgtga ccagaccaat cttaccaaac acgttggtat agacgggcaa cgtctcaagc
    10081 ggatcggtaa tgttgtccgg caccgcggta aatgttgcca catagccgcc cagcaagaac
    10141 gcggcagcct gcgtcaggaa ccacatcccg agaataaagc ccatcaaatg ctgcggcacc
    10201 agggcagcaa tcatcgccag gccaagggcg ctaataaaca gttcacctaa gctctggaat
    10261 aagtacacca gcacgataaa ccatggcgat gtcagcccct gggcatccgc aaaccacatt
    10321 cccgcagctg cagccgtcaa aaagcccaga gagcacataa acatgccgag agtaaatttc
    10381 atcggcatcg agaggtcttt gcctttgtta cccagatgcg tgtaaatgcc tgccagtatt
    10441 gggctggcga gtaccaccca gaacgggtta agcgcctgga agctgaccgg gttgatggaa
    10501 aaaccgagaa tttcatgatg cacgttgttg atggcaaaga agttcagcga tgttggcatc
    10561 tgggcgtaga gaatgtaaaa caccaccgct tcgagcatca ggacaaaggc gacaaacatt
    10621 ttattgcgcc cggttttatc cagcttgaat gcctgacgaa agaagatgat ggtgacgacg
    10681 atggagagaa caatcagcac cagattggcg acttctacgt tgtgcatcag ccatgcacag
    10741 acgaagatca tcaccacgct gccaagtaat acgtacaaca gtttgctgaa gctcatcggc
    10801 ttgaagtcgg gttcagaacc aatgtctttc accattccac gacaggcgat gtaaaccagt
    10861 aatgcgataa ttaaccccgc cccgcacagg ttgtaggtga ctgaataacc gaatctatca
    10921 gcgatcacag gggccagcga taacgctatc aacgagccga tattgatcga catatagaac
    10981 agggtgaatg cgccatcaag ccgcggatct ttcggcggat agcacttcga aagcaagctg
    11041 gctgggttag ctttaaacag gccgttaccg acagcgatag tccccagggc gatgaaaatc
    11101 aggtcaggct taagtagcga catgccggtc atgaagtagc caatcgccag cacaagtgct
    11161 ccgagaacaa tggtgcgttt ggtccccagc aggtggtcgc cgacatagcc gccaatggaa
    11221 atgaggccat agaccagcgc agcaaaagca ccaaaagtga caaaagcctg ctcttgcgag
    11281 aatccaagct gtttaacgaa gaaaaccgcc agtacgccct gcacgccgta gtagccgaat
    11341 cgctcccata actcgacaaa aaagatcatg aaaaatgggc gaggttgctg cagcatcccc
    11401 atgggtgttg ttgtattcat atttattaac cttccaatac catcctgaaa agtatgaacg
    11461 cgtaagggat aacgcgcgaa aaagtttaca tgtgtcagag attcttaata ttgatgcggt
    11521 gaatagatta atacactatt acaacagaaa ataaccagct gatcacacta atgatggaaa
    11581 atatgatggt gttaaatgtt gtattggcag gagattttga ttgcgtacgc agatcgtagg
    11641 ccagataagg ggtttacgct gcatcaggta acaaggcgcg ccaaaaagca aaacgcccgc
    11701 atatgcgggc gttcaggaac acgtcgtggg gggatgatta ttcttcttcg tcgcgcagcg
    11761 gaacaatcag catatcaacg tgaacggtgt tgatcagctg acgtgcggaa gacattagtt
    11821 tgctccagaa gtcctggtgg tgaccacaaa ccaccagatc catatcgtat ttcttgattg
    11881 catcgaccag aacctggccc aggtcgccgc tgccgctcag ggtttcagtg attgggtagc
    11941 ctgcattagt ggaaagctcg gtcagcgcat gatgtgtctc ttcagagatg cgtttctgca
    12001 tatcacccag attcacatca ataagcccgg tgtataggtc agagtagttt acatctacgt
    12061 ggatcagaga aactttcgca ttgtaggggc gagccataga gactgctttc tctaccagaa
    12121 ctttgctttc cggggagagg tcgaccgcga tgagaatgtg tttataagcc atagtgttac
    12181 tccttccata aagttgtcga tgactggcca gctagcgttt cttgtgccgt tacgtcaccc
    12241 gcgtcctgcg aactacgtgc gcggggctaa cccagccgta aagattcagt gttaagacca
    12301 tccttacctt atagcgaccc ggatgatccg tcaatccgcc ttgcttactc gttagataaa
    12361 caaattttcg acatgaatat attgatagtg gttaaccttc tggaaaaaaa acaacctgat
    12421 ctcctacact atctatagag ccgctcggat gttggtcacc acaaaagcgg tttctccagg
    12481 acctggtgtt aactgattgg cagcgtatcg ggagcggtag ccccggggtg gaactccgcg
    12541 ggcaggtcgc cggggaggag gtatgataag caccgtcgca ttattttggg ctttatgtgt
    12601 cgtttgcatt gttaacatgg cgcgctattt ctcatcacta cgcgcgttgt tagtggtact
    12661 gcgtaactgc gatccattgc tctatcaata tgttgatgga gggggctttt ttacctcaca
    12721 tggccaaccc aacaaacagg tgcgtctcgt ttggtatatc tatgcccaac gttatcgcga
    12781 tcatcacgat gatgagttta ttcgccgctg tgagcgggtg cgtcggcagt ttattctgac
    12841 tagcgcattg tgtggtctgg tggtggtcag cctgattgca ttgatgattt ggcattaagc
    12901 acttcagcaa taataacgca taaaaaaagc gggccagtaa actgacccgc tcgttttggt
    12961 gcgtacgatt acaggaactg caaggagagc cagtacagcc cgccggaaag cagtaccgca
    13021 gccggaaggg taaacaccca ggccatcaga atactggtta cggttttacg ctgtaagccg
    13081 ccgccatcta ccaccatcgt ccccgcgaca gaagaggaga gtacgtgagt agtggaaacc
    13141 ggcatcccgg tataactcgc caggccgata gacactgccg ccgtcatctg ggcagacatc
    13201 ccctgagcgt aggtcatgcc tttcttaccg attttctcac cgatagtcgt tgccacacgg
    13261 cgccagccaa tcatcgtacc gatacctaac gccagcgcga ccgccatgat gatccacacc
    13321 ggtgcatact cgatggtgct aagcatgtca gacttcagtt tcttcaacag gcgctgatcg
    13381 tcagcactca cgccaggcat cttcaccact ttgtcgatag tgtcagaaac gcacagcata
    13441 atgcggcgca tctggctacg ttgatcaagc gacagcttgt cgtagctttc cacatcggtg
    13501 gtcaacatac ctttcaggcg gttgagcgcg ttaatggtat tcgacggatg gcagtggaac
    13561 tccgcaggtt gcgttgcgcc agcttccgga gccggtacta actgatcagc accggtagcc
    13621 tgtttgagca gcgcaggatg ctgctcaaag taagcttcga cgttgttgat ggcatcacgg
    13681 gtacgggtga tttcgtagcc agtggcattc atgttcacca cgaagcctgc tggcgcgacg
    13741 ccaatcaata ccaacataac cagaccaatg cctttctgac catcgttcgc gccgtgcgaa
    13801 aacgccacgc cgatagcgga aaggatcagc gcgatacgcg tccagaacgg cggctttttc
    13861 ttgccgtctt tcttttcacg ctccgctggg gtcaggtgga tacgggcgcg tttcttggtg
    13921 ccgctccagt agcgacgcag caagaaaatc agaccgccag caaacaccag gccgacaata
    13981 ggggaaacga tcagagaacc gaaaatactt aatactttcg ggatattgag tgcatccacc
    14041 actgacgtcc cggtcatcaa cgcattggtt aaaccaatcc cgatgatcgc gccaatcagc
    14101 gtatgagagc tggatgcagg taaaccaaag taccaggtac ccaggttcca gataatcgcc
    14161 gccagcaaca tagagaacac catggcaagg ccatgagacg atcccatatt aagcagcaga
    14221 tccgtcggca gcatatgcac aatggcatag gcaacactca gaccacccag caaaacaccc
    14281 aaaaagttga acaccgccgc cataaccacg gcgagctgag aacgcatcgc gcgggtatag
    14341 ataacggttg ccacggcgtt ggctgtgtca tggaaaccat tgatggcttc gtagaacagc
    14401 acaaaagcca gtgcaagcaa taataacagc ccggtatgca aatccaggcc agcaaacaaa
    14461 tgtagcatag gacgttacgc cattttgagg acatgaacgc ggcgcattat cagtgacttt
    14521 cgcggcgcgg gcaaagtgaa atatagactt tttttgattt gcctcctgta tggatttcac
    14581 tcaaaaaata attatcttat ataattcagg caaatacttc cttttagtaa tattgatgct
    14641 ggtgcgacca ctgaggaatc tttacaattc acgcccgttt tttctaagag gagcgcaacg
    14701 tggaaaggtt tgatgccatt attataggcg ctggtgcggc gggtatattc tgttctgcgc
    14761 tggcaggtca ggcaggacgc cgggttctgc tgatcgataa tggtaaaaaa ccagggcgca
    14821 aaatccttat gtctggcggt gggcgctgca actttaccaa cctttatgtc gaaccaggcg
    14881 cttatctgag ccagaatccg catttttgta agtctgcact cgcgcgtttt acccagtggg
    14941 atttcattga tctggtcaat aaacacggca tcgcctggca cgagaaaacg ttaggacaac
    15001 tcttctgcga tgactccgcg cagcagattg tcgacatgct ggtggatgag tgcgagaagg
    15061 gcaatgtaac cttcagattg cgtagcgaag tgctgagtgt ggcgaaggat gaaacaggct
    15121 tcacgcttga actgaacggc atgactgtcg gttgcgaaaa gctggtcatc gcgaccggtg
    15181 ggctgtcaat gccggggctg ggcgcgtcgc cgtttggtta taagattgcc gaacaatttg
    15241 gcctcaacgt gctgccgacc cgcgcgggtc tggtgccatt cactctgcat aaaccgttgc
    15301 tcgaagagtt acaggtgctg gcgggcgtgg cggtgccttc cgtgattacc gctgaaaacg
    15361 gcatcgtttt ccgtgagaac ttactcttca cccatcgcgg cttgtctgga ccggcggtgt
    15421 tgcagatttc cagctactgg caaccgggtg aatttgtcag tatcaatctg ctaccggatg
    15481 tggatctcga aaccttcctg aatgagcagc gtaacgcaca tccgaatcag agcctgaaaa
    15541 acacactggc ggttcatcta ccgaagcggt tggttgaacg cttacagcaa ctcgggcaaa
    15601 tcccggatgt ttcgctaaaa cagctcaacg tgcgtgacca acaggcactg attagcacat
    15661 tgaccgactg gcgcgtacaa cccaacggca ctgaaggcta tcgcactgcc gaagtgacgc
    15721 tcggcggcgt ggacaccaac gaactctctt cacggacgat ggaagcgcgc aaagtgcctg
    15781 ggctgtactt catcggcgaa gtgatggacg ttaccggctg gctggggggc tataacttcc
    15841 agtgggcgtg gtcgagtgcg tgggcttgtg cgcaggattt gattgcagcg aagtcgtcct
    15901 gacctgttac ctaaagatga aaattattag agccgcatta aaaatgagct aattttgata
    15961 gtggctatct tgtgattatt ttctaatgag cccgtgaact gaaaccctcc aggcttaata
    16021 taaggtggaa ggaaaggtga ttgaaaactc acccagtggc cagatcttta taaaatatga
    16081 acaggttgaa aaaaacagta actttgttgt ttttttatcc ttaaccacta tgcattaatg
    16141 ctgcgttatt tcatgatgcc taagaaaaac cagcgttacg caaatggtca acgctggttt
    16201 tatccggtac gttgcaatta ttttttagca gaacctgctt ctaatattga aacgattgag
    16261 aacaacgtaa agcataccgc tcctaaaccg accaaaaccc gcgaaggaat aaaatatccc
    16321 atgtcggtct gcgccatttc cgcaagaaac gatgccagga aaaggcaaaa caggcaggtg
    16381 aagacgggaa tcatcggtat tctgttggct aacgaacagg tacgtctcca taccagtgcc
    16441 agtagccaga cttttgagaa tatgctgtaa cagatcattc cgaggcaaat aagaataatg
    16501 ccgggagcca gtcgggcgct tgcatcggaa ctgactaaga cgtatatccc ctgcagtacc
    16561 gtgattgagc cgagaaaaat aacccaataa caccacagcc agtgttcttt agttgaaaac
    16621 gtattacgtg tttgatggac aattgtggca acaaggccaa ttagacaggc acagattgcg
    16681 gttaacccaa gcaatacgtg acccgcgaca taatgcggag ttatgtcagc actacgtaac
    16741 agcgtaatag accaaatgaa accgagcagg gtgagtaaaa cgggaacggc aatgaggcaa
    16801 ttaccgatta atgaagaata agcctgtacc ggcgttccat cgctcttgct ccccgctgca
    16861 tttttgggaa tgagcagaaa gtgaccggat gacgctgcca ccgtcgatac acaggcggca
    16921 atcataccaa cgccgaaaat aacatggccg gcgacaaact cgtctgccat cacatcattg
    16981 cctgctaaca gtgcccaacc ccatatcatg gtgataattg accccgcata gccaataatg
    17041 gggaacaatg tattgtaaaa cgtattaacg ccgcgcgtga gctgcgaaat gataataaat
    17101 gcggtagtga ataatgccag gcatatggcc gccagagaaa tcagcacatg acccgcgacg
    17161 aaatactcgc tttgccctga actttccagc acaaagccac ctaacgcgat gcaaattaat
    17221 cccataatca aagggattaa tttgaaaagc cacccgatat atatgttcac tttaaactcc
    17281 tcaggtatcc ctgctaataa tgaaatgtgc attaatgata atttcagcct gttaatataa
    17341 cgacgagata tcattaaaga caaatgcata gcataactat agcggggttt actgtgccga
    17401 gtgccatttt ttaccggtta
//
LOCUS       DAPOAV010000089        17374 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.089, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000089 DAPOAV010000000
VERSION     DAPOAV010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17374
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.089"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(182..1774)
                     /gene="lsrK"
                     /locus_tag="RN951_003512"
     CDS             complement(182..1774)
                     /gene="lsrK"
                     /locus_tag="RN951_003512"
                     /EC_number="2.7.1.189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416028.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer-2 kinase"
                     /protein_id="HDX2528462.1"
                     /translation="MARLFTLSESKYYLMALDAGTGSIRAVIFDLEGNQIAVGQAEWR
                     HLAVPDVPGSMEFDLNKNWQLACECMRQALHNAGIAPEYIAAVSACSMREGIVLYNNE
                     GAPIWACANVDARAAREVSELKELHNNTFENEVYRATGQTLALSAIPRLLWLAHHRSD
                     IYRQASTITMISDWLAYMLSGELAVDPSNAGTTGLLDLTTRDWKPALLDMAGLRADIL
                     SPVKETGTLLGVVSSQAAELCGLKAGTPVVVGGGDVQLGCLGLGVVRPAQTAVLGGTF
                     WQQVVNLAAPVTDPEMNVRVNPHVIPGMVQAESISFFTGLTMRWFRDAFCAEEKLIAE
                     RLGIDTYTLLEEMASRVPPGSWGVMPIFSDRMRFKTWYHAAPSFINLSIDPDKCNKAT
                     LFRALEENAAIVSACNLQQIADFSNIHPSSLVFAGGGSKGKLWSQILADVSGLPVNIP
                     VVKEATALGCAIAAGVGAGIFSSMAETGERLVRWERTHTPDPEKHELYQDSRDKWQAV
                     YQDQLGLVDHGLTTSLWKAPGL"
     gene            complement(1853..2806)
                     /gene="lsrR"
                     /locus_tag="RN951_003513"
     CDS             complement(1853..2806)
                     /gene="lsrR"
                     /locus_tag="RN951_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LsrR"
                     /protein_id="HDX2528463.1"
                     /translation="MTINDSAISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTR
                     LKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRL
                     GIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGI
                     GQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDD
                     ATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTNIKIHNELIGLPLSALKTI
                     PVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS"
     gene            3055..4590
                     /gene="lsrA"
                     /locus_tag="RN951_003514"
     CDS             3055..4590
                     /gene="lsrA"
                     /locus_tag="RN951_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter ATP-binding
                     protein LsrA"
                     /protein_id="HDX2528464.1"
                     /translation="MQTSDTRALPLLCARSVYKQYSGVNVLKGIDFTLHQGEVHALLG
                     GNGAGKSTLMKIIAGITPADSGTLEIEGNNYVRLTPVHAHQLGIYLVPQEPLLFPSLS
                     IKENILFGLAKKQLSMQKMKNLLAALGCQFDLHSLAGSLDVADRQMVEILRGLMRDSR
                     ILILDEPTASLTPAETERLFSRLQELLATGVGIVFISHKLPEIRQIADRISVMRDGTI
                     ALSGKTSELSTDDIIQAITPAVREKSLSASQKLWLELPGNRPQHAAGTPVLTLENLTG
                     EGFRNVSLTLNAGEILGLAGLVGAGRTELAETLYGLRTLRGGRIMLNGKEINKLSTGE
                     RLLRGLVYLPEDRQSSGLNLDASLAWNVCALTHNLRGFWAKTAKDNATLERYRRALNI
                     KFNQPEQAARTLSGGNQQKILIAKCLEASPQVLIVDEPTRGVDVSARNDIYQLLRSIA
                     AQNVAVLLISSDLEEIELMADRVYVMHQGEITHSALTERDINVETIMRVAFGDSQRQE
                     ASC"
     gene            4584..5612
                     /gene="lsrC"
                     /locus_tag="RN951_003515"
     CDS             4584..5612
                     /gene="lsrC"
                     /locus_tag="RN951_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter permease LsrC"
                     /protein_id="HDX2528465.1"
                     /translation="MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSVQTLTMVYSSA
                     QILILLAMGATLVMLTRNIDVSVGSITGMCAVLLGMLLNAGYSLPVACVATLLLGLLA
                     GFFNGVLVAWLKIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLLGVS
                     AIGWLTIILVAFMAWLLAKTAFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMA
                     ALTGIVFASQIGFIPNQTGTGLEMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQID
                     SVLVLLRIPAWWNDFIAGLVLLAVLVFDGRLRCALERNLRRQKYARFMTPPPSVKPAS
                     SGKKREAA"
     gene            5612..6604
                     /gene="lsrD"
                     /locus_tag="RN951_003516"
     CDS             5612..6604
                     /gene="lsrD"
                     /locus_tag="RN951_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter permease LsrD"
                     /protein_id="HDX2528466.1"
                     /translation="MRIRYGWELALAALLVIEIVAFGAINPRMLDLNMLLFSTSDFIC
                     IGIVALPLTMVIVSGGIDISFGSTIGLCAIALGVLFQSGVPMPLAILLTLLLGALCGL
                     INAGLIIYTKVNPLVITLGTLYLFAGSALLLSGMAGATGYEGIGGFPMAFTDFANLDV
                     LGLPVPLIIFLICLLVFWLWLHKTHAGRNVFLIGQSPRVALYSAIPVNRTLCALYAMT
                     GLASAVAAVLLVSYFGSARSDLGASFLMPAITAVVLGGANIYGGSGSIIGTAIAVLLV
                     GYLQQGLQMAGVPNQVSSALSGALLIVVVVGRSVSLHRQQIKEWLARRANNPLP"
     gene            6616..7638
                     /gene="lsrB"
                     /locus_tag="RN951_003517"
     CDS             6616..7638
                     /gene="lsrB"
                     /locus_tag="RN951_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter substrate-binding
                     protein LsrB"
                     /protein_id="HDX2528467.1"
                     /translation="MTLHRFKKIALLSALGIAAISMNVQAAERIAFIPKLVGVGFFTS
                     GGNGAQQAGKELGVDVTYDGPTEPSVSGQVQLINNFVNQGYNAIIVSAVSPDGLCPAL
                     KRAMQRGVRVLTWDSDTKPECRSYYINQGTPAQLGGMLVDMAARQVNKDKAKVAFFYS
                     SPTVTDQNQWVKEAKAKIAKEHPGWEIVTTQFGYNDATKSLQTAEGILKAYSDLDAII
                     APDANALPAAAQAAENLKNDKVAIVGFSTPNVMRPYVERGTVKEFGLWDVVQQGKISV
                     YVADALLKKGSMKTGDKLDIKGVGQVEVSPNSVQGYDYEADGNGIVLLPERVIFNKEN
                     IGKYDF"
     gene            7665..8540
                     /gene="lsrF"
                     /locus_tag="RN951_003518"
     CDS             7665..8540
                     /gene="lsrF"
                     /locus_tag="RN951_003518"
                     /EC_number="2.3.1.245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxy-5-phosphonooxypentane-2,4-dione
                     thiolase"
                     /protein_id="HDX2528468.1"
                     /translation="MADLDDIKDGKDFRTDQPQKNIPFTLKGCGALDWGMQSRLSRIF
                     NPKTGKTVMLAFDHGYFQGPTTGLERIDINIAPLFEHADVLMCTRGILRSVVPPATNR
                     PVVLRASGANSILAELSNEAVALSMDDAVRLNSCAVAAQVYIGSEYEHQSIKNIIQLV
                     DAGMKVGMPTMAVTGVGKDMVRDQRYFSLATRIAAEMGAQIIKTYYVEKGFERIVAGC
                     PVPIVIAGGKKLPEREALEMCWQAIDQGASGVDMGRNIFQSDHPVAMMKAVQAVVHHN
                     ETADRAYELYLSEKQ"
     gene            8564..8854
                     /gene="lsrG"
                     /locus_tag="RN951_003519"
     CDS             8564..8854
                     /gene="lsrG"
                     /locus_tag="RN951_003519"
                     /EC_number="5.3.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione
                     isomerase"
                     /protein_id="HDX2528469.1"
                     /translation="MHVTLVEINVHEDKVDEFIEVFRQNHLGSVQEEGNLRFDVLQDP
                     EVNSRFYIYEAYKDEDAVAFHKTTPHYKTCVAKLESLMTGPRKKRLFNGLMP"
     gene            8911..9669
                     /gene="tam"
                     /locus_tag="RN951_003520"
     CDS             8911..9669
                     /gene="tam"
                     /locus_tag="RN951_003520"
                     /EC_number="2.1.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trans-aconitate 2-methyltransferase"
                     /protein_id="HDX2528470.1"
                     /translation="MSDWNPSLYLHFSAERSRPAVELLARVPLENVEYVADLGCGPGN
                     STALLQQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIRNWQPVQALDLIFANAS
                     LQWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLA
                     GVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQLFL
                     KRYHQMLEEQYPLQENGQILLAFPRLFIVARRME"
     gene            complement(9673..10587)
                     /locus_tag="RN951_003521"
     CDS             complement(9673..10587)
                     /locus_tag="RN951_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416037.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bestrophin family inner membrane protein"
                     /protein_id="HDX2528471.1"
                     /translation="MIVRPQQHWLRRIFVWHGSVLSKISSRLLLNFLFSIAVIFMLPW
                     YTHLGIKFTLAPFSILGVAIAIFLGFRNNAGYARYVEARKLWGQLMIASRSLLREVKT
                     TLPDSASVREFARLQIAFAHCLRMTLRKQPQAEVLAHYLKTEDLQRVLASNSPANRIL
                     LIMGEWLAVQRRNGQLSDILFISLNDRLNDISAVLAGCERIAYTPIPFAYTLILHRTV
                     YLFCIMLPFALVVDLHYMTPFISVLISYTFISLDCLAEELEDPFGTENNDLPLDAICN
                     AIEIDLLQMNDEAEIPAKILPDRHYQLT"
     gene            complement(10794..12245)
                     /gene="uxaB"
                     /locus_tag="RN951_003522"
     CDS             complement(10794..12245)
                     /gene="uxaB"
                     /locus_tag="RN951_003522"
                     /EC_number="1.1.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HDX2528472.1"
                     /translation="MKTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDL
                     NSGVVVVRPIETSFPPSLSTQDGLYTTIIRGLNEKGEAVSDARLIRSVNREISVYSEY
                     DEFLKLAHNPEMRFVFSNTTEAGISYHAGDKFDDAPAVSYPAKLTRLLFERFSHFNGA
                     LDKGWIIIPCELIDYNGDALRELVLRYAQEWALPEAFIQWLDQANSFCSTLVDRIVTG
                     YPRDEVAKLEEELGYHDGFLDTAEHFYLFVIQGPKSLATELRLDKYPLNVLIVDDIKP
                     YKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKAIYEEIIPVLDLPRD
                     ELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQKANGTLPARLTFA
                     LAALIAFYRGERNGETYPVQDDAHWLERYQQLWSQHRDRVIGTQELVAIVLAEKDHWE
                     QDLTQVPGLVEQVANDLDAILEKGMREAVRPLC"
     gene            complement(12472..13458)
                     /locus_tag="RN951_003523"
                     /pseudo
     CDS             complement(12472..13458)
                     /locus_tag="RN951_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310156.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
     gene            complement(13531..13890)
                     /locus_tag="RN951_003524"
     CDS             complement(13531..13890)
                     /locus_tag="RN951_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4186 domain-containing protein"
                     /protein_id="HDX2528473.1"
                     /translation="MQSLDPLFARLSRSKFRSRFRLGMKERQYCLEKGAPVIEQHAAD
                     FVAKRLAPALPANDGKQTPMRGHPVFIAQHATATCCRGCLAKWHNIPQGVSLSEEQQR
                     YIVAVIYHWLVVQMNQP"
     gene            complement(13890..14816)
                     /gene="glsB"
                     /locus_tag="RN951_003525"
     CDS             complement(13890..14816)
                     /gene="glsB"
                     /locus_tag="RN951_003525"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase B"
                     /protein_id="HDX2528474.1"
                     /translation="MAVAMDNAILENILRQVRPLIGQGKVADYIPALATVDGSRLGIA
                     ICTVDGQLFQAGDAQERFSIQSISKVLSLVVAMRHYSEEEIWQRVGKDPSGSPFNSLV
                     QLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVRGLSGVSDISYDTVVARS
                     EFEHSARNAAIAWLMKSFGNFHHDVTTVLQNYFHYCALKMSCVELARTFVFLANQGKA
                     IHIDEPVVTPMQARQINALMATSGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAI
                     AVWSPELDDAGNSLAGIAVLEQLTKQLGRSVY"
     gene            complement(14880..16268)
                     /gene="sad"
                     /locus_tag="RN951_003526"
     CDS             complement(14880..16268)
                     /gene="sad"
                     /locus_tag="RN951_003526"
                     /EC_number="1.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate-semialdehyde dehydrogenase"
                     /protein_id="HDX2528475.1"
                     /translation="MTITPATHAISINPATGEQLSVLPWAGADDIENALQLAAAGFRD
                     WRETNIDYRAEKLRDIGKALRARSEEMAQMITREMGKPINQARAEVAKSANLCDWYAE
                     HGPAMLKAEPTLVENQQAVIEYRPLGTILAIMPWNFPLWQVMRGAVPIILAGNGYLLK
                     HAPNVMGCAQLIAQVFKDAGIPQGVYGWLNADNDGVSQMIKDSRIAAVTVTGSVRAGA
                     AIGAQAGAALKKCVLELGGSDPFIVLNDADLELAVKAAVAGRYQNTGQVCAAAKRFII
                     EEGIASAFTERFVAAAAALKMGDPRDEENALGPMARFDLRDELHHQVEKTLAQGARLL
                     LGGEKMAGAGNYYPPTVLANVTPEMTAFREEMFGPVAAITIAKDAEHALELANDSEFG
                     LSATIFTTDETQARQMAARLECGGVFINGYCASDARVAFGGVKKSGFGRELSHFGLHE
                     FCNIQTVWKDRI"
     gene            16369..17250
                     /locus_tag="RN951_003527"
     CDS             16369..17250
                     /locus_tag="RN951_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX2528476.1"
                     /translation="MDLTQLEMFNAVAEAGSITQAAAKVHRVPSNLTTRLRQLETELG
                     VDLFIRENQRLRLSPAGHNFLRYSQQILALVDEARSVVAGDEPQGLFSLGSLESTAAV
                     RIPATLAEFNRRYPKIQFSLSTGPSGTMLDGVLEGKLNAAFIDGPINHTAIDGIPVYR
                     EELMIVTPQGYAPVTRASQVNGSNIYAFRANCSYRRHFESWFHADGAAPGTIHEMESY
                     HGMLACVIAGAGIALIPRSMLESMPGHHQVEAWPLAEQWRWLTTWLVWRRGAKTRPLE
                     AFIQLLDVPDSARQGYQ"
BASE COUNT         4290 a         4455 c         4370 g         4259 t
ORIGIN      
        1 aataagggtt gtgcttaatg ctttaagaaa aatagcaatt ttctcttgaa tatagtactg
       61 gtgatggaac gatgaatctg caagctggct tttaacaagc cagctctaaa agaagggaaa
      121 taagaataac tatactcaaa aactaacagc cacggtcatc atgatgtggc tgtcaatgaa
      181 actataaccc aggcgctttc cataacgacg tcgtcagtcc atgatcaacc agccccagct
      241 gatcctgata aactgcctgc cacttatcgc gtgaatcctg ataaagttca tgcttttccg
      301 ggtctggtgt gtgcgtccgt tcccagcgaa ccaggcgttc tccggtttct gccattgatg
      361 aaaaaattcc ggcaccgacg ccagctgcaa tggcacatcc taatgcagtg gcttctttga
      421 ccaccggaat attgacgggt aatcccgaga catcagcgag aatttgactc cataatttcc
      481 cttttgaacc tccgcctgca aagactaacg atgaaggatg aatattcgag aaatcagcaa
      541 tttgctgcaa gttacacgct gatacaatcg ccgcattttc ttccagcgca cggaacaatg
      601 tcgctttgtt acatttatcc gggtcaatgg acaagttaat aaaggaaggc gcagcgtgat
      661 accaggtttt aaagcgcatt ctgtcggaga agatcggcat tacgccccac gacccaggcg
      721 gcacccgact ggccatctct tccagcagcg tataggtgtc gatgcctaaa cgttcggcaa
      781 tcagtttttc ttcggcacag aaagcatcgc ggaaccagcg catggtgagt ccggtaaaaa
      841 agcttataga ttcagcttgt accatgccag gaataacatg aggattaacg cgcacgttca
      901 tttctgggtc tgtcaccggc gcggctaaat ttacaacttg ctgccagaat gtgccgccaa
      961 gaaccgcggt ttgtgccgga cgcacaacgc ctaacccaag gcaaccaagc tgcacgtcgc
     1021 ctcctccaac gaccaccgga gtgcccgcct tcagaccgca gagttccgcc gcttgtgaac
     1081 ttaccacgcc cagcaatgtg ccggtttctt tgacaggaga aagaatatcg gcacgtaggc
     1141 cagccatatc cagcaatgca ggtttccagt cacgggtggt tagatcaaga agtcccgtgg
     1201 tgccagcgtt agagggatcc accgccagtt cgccgctgag catataggcc agccagtcgc
     1261 tgatcatggt gatggttgat gcctgacggt aaatatcgga acgatggtgc gccagccaaa
     1321 gtaatctggg gatggcactt aaagccagtg tttgtccggt cgcgcgataa acttcgtttt
     1381 caaaggtatt gttgtgcagt tctttaagtt cgctaacttc gcgtgccgct ctggcatcca
     1441 cattggcgca ggcccagatc ggggctcctt cattattata taaaacaatg ccttcacgca
     1501 tcgaacatgc cgaaacggca gcgatatact ccggggctat gccggcgttg tgcagcgcct
     1561 ggcgcataca ctcacacgcc agttgccagt ttttgttgag atcaaattcc atagaaccag
     1621 gaacgtccgg tactgccaga tgccgccact ccgcctgtcc cactgctatt tgattgcctt
     1681 ccaggtcgaa tatcacagcc cgaatacttc cggtgcctgc atccagcgcc atcaggtagt
     1741 actttgattc tgaaagggta aagagtcgag ccattagatt atcctcggct tatgcgttct
     1801 gtctgttcct ctatacgttc tccatcattc ccggtaataa ggtcatgcaa atttaactac
     1861 gtaaaatcgc cgctgctgtg tcctgatcgg taaccagtgc gttgatataa ccgcctttca
     1921 ttgcagcggc aattgcttcg gctttatttt ctccccctgc cacgccaacc cggacgggta
     1981 tggtcttcag cgcgcttaaa ggtaagccaa tcagttcgtt atgtattttg atattcgtga
     2041 caacgtcacc ttttgcatca aaaaagtagc ctaaaatgtc gccaaccgcc ccttttcggc
     2101 caatcattaa ctgttcgccc tggctgatat aaccggagcg aatgattgtc gcatcgtcct
     2161 gttgactcac agcaccaatg ccgacaatcg ccacatccgc tgcttgcgcg gctaacagaa
     2221 catctttgac gcaattttca ttttttagcg tacgggcaat gtcagcggag gatgcccgca
     2281 acggagccgg aataatattc acactgcacg ccgcgttaag ctgcccgatt cccgtcatat
     2341 aagaaccgac gccaccggag agcgtgacca ggcgaatttg ctgtgacgaa ataaaaccac
     2401 ttaagcgttg cagcgtattc atggttgcct cgccaaaacc aatcgccagc atctgttgtg
     2461 gttgaagtaa actcatcaac atatgcgccg cgcctatccc cagtcgccca ccgacatcag
     2521 catccgcaag cccagggatc acccggacat gttgcagcga aaactgacga cgtaattgag
     2581 tttcatattc cagacagcct tcaaagcgag aattaatctg tacgcgaata atgccggact
     2641 gatgcccttt ctccagcaat cgcgacactt tcaaacgtgt caggccgaga cgatcgctga
     2701 tctcgctctg ggtcagcccg tcgtgatagt aaaaccacgc gatccgcgcg acctgttctt
     2761 cttcacacat tccctgttct gaaattgccg aatcgttgat tgtcataatt cattcttcac
     2821 tttgaacata tttaaatctt taatgcaatt gttcagttct tgctcattta tatctgtgat
     2881 ggcaaccaca gtttgactct acgagcatga acaaacgcaa ccgtgaaaat caaaatagca
     2941 taaattgtga tctattcgtc ggaaatatgt gcaatgtcca cctaaggtta tgaacaaatt
     3001 aaaagcagaa atacatttgt tcaaaactca cctgcaaaac tgaacggggg aaatatgcaa
     3061 acgagtgata cccgcgcgtt accgctactt tgcgcccgct cggtttataa acagtattca
     3121 ggggtcaatg tcctgaaagg catcgatttt acgttgcatc agggggaggt ccacgccctg
     3181 ctcggcggca atggtgccgg taaatcgacg ttaatgaaga ttattgccgg tattacccct
     3241 gctgatagcg gtacgctgga gattgagggc aacaactacg tcagattaac gccagttcat
     3301 gctcatcagc tgggtattta tctcgttccc caggaaccgc tgcttttccc aagcctgtcg
     3361 ataaaagaaa acatcctgtt tgggctggca aaaaaacagc tctccatgca gaaaatgaag
     3421 aacttgctgg cggcgctggg ctgccagttt gatctgcata gtctggcagg atcgctggat
     3481 gtcgccgatc gccaaatggt ggaaatcctc cgcgggctga tgcgcgactc gcggattctg
     3541 atcctcgatg aacctaccgc ctcgcttacc cctgcggaaa ccgaacgctt gtttagtcgc
     3601 ttgcaagagc tgcttgctac tggcgtgggt attgttttta tctcgcataa gctgccggaa
     3661 attcgccaga ttgccgatcg aattagcgtg atgcgcgacg gaaccatcgc cttaagcggc
     3721 aaaaccagcg aactgtctac cgacgacatt attcaggcca tcaccccagc ggtacgggaa
     3781 aaatcgctct ctgccagcca aaaattatgg ctggagttac ctggtaaccg cccacaacat
     3841 gccgccggaa cgccggtgct gacactggaa aatctgaccg gcgaaggttt caggaatgtc
     3901 agcctgacgc tcaatgccgg agaaattctg ggcctggctg ggctggtggg ggccggacgc
     3961 acagaactgg ccgagacgct ctatggtctg cgtactttgc gtggcggacg cattatgctg
     4021 aatggtaaag agatcaataa attatccact ggagaacgtt tactgcgcgg tctggtttat
     4081 ctgccggaag atcgccagtc atccggactg aatctcgatg cttcgctggc ctggaacgtc
     4141 tgcgccctta ctcataacct tcgtggattc tgggcgaaaa ccgcgaaaga taatgccacc
     4201 ctggaacgtt atcgtcgggc gctgaatatt aaattcaacc aaccggaaca agctgcacgg
     4261 acattatccg gtggcaacca gcaaaaaatc ctcattgcca aatgcctgga agcttcgccg
     4321 caagtattga ttgtcgatga gccgacgcgc ggcgtggatg tctcggcccg taatgatatc
     4381 taccagctgt tgcgcagcat cgccgcacaa aatgtggctg tgctgcttat ctcctccgac
     4441 ctggaagaga tcgaactgat ggcagatcgt gtgtatgtga tgcatcaggg cgaaattacc
     4501 cactctgcac tgaccgagcg cgatattaat gtcgagacta ttatgcgcgt tgccttcggc
     4561 gatagtcagc gtcaggaggc gtcatgctga agtttattca gaacaaccgt gaaatcacgg
     4621 cactgctggc ggtggtgctg ctgtttgtat tacccggttt tctcgaccgc cagtatttaa
     4681 gtgtgcaaac gctgaccatg gtttatagca gcgcgcaaat cctgatcctg ctggcaatgg
     4741 gcgcgacgct ggtaatgctt acgcgcaata ttgatgtttc agtgggttcg attaccggaa
     4801 tgtgcgcggt gctgttgggg atgttactga acgcaggata ttcactacct gttgcttgtg
     4861 tcgcgacttt actgcttggt ttgctcgcgg gatttttcaa cggtgtcctg gtcgcgtggc
     4921 taaagatccc tgccattgtt gccacccttg gcacgttagg gttgtacaga ggcatcatgt
     4981 tgctgtggac tggcggcaaa tggattgaag ggttacccgc cgaactgaaa cagctctccg
     5041 ccccgctgct gcttggcgtt tcagcaattg gttggttgac gataattctg gtggcattta
     5101 tggcctggct gctggcaaag acggcgtttg gacgcagttt ttatgccacg ggcgataatt
     5161 tacagggcgc tcgtcaactg ggcgttcgta ctgaagccat tcgcattgtg gcattttcgt
     5221 tgaacggctg catggcggca ctgacgggaa ttgtgtttgc ttcgcagatt ggttttatcc
     5281 ccaaccagac cggtaccggg ctggagatga aagcaattgc agcctgcgtg ctgggcggca
     5341 ttagtttgct cggtggttcc ggtgcgatca ttggtgcggt actcggcgca tggttcctga
     5401 cgcagatcga tagcgtactg gtgctgttgc gcattccggc atggtggaat gattttatcg
     5461 cgggtctggt tctgctggcg gtgctggtgt ttgatggacg cctgcgttgt gcgctggaac
     5521 gtaatctacg gcggcaaaaa tatgcccgct ttatgacgcc accgccatcc gttaaacccg
     5581 cttcgtcagg taaaaaacgg gaggccgcat aatgcgtatt cgctacggtt gggaactggc
     5641 tcttgccgca ctgctcgtta ttgagattgt cgcatttggt gcaattaacc cgcgaatgtt
     5701 agatctcaat atgttgctgt tcagcaccag tgactttatc tgcattggca ttgtcgccct
     5761 accgctaacg atggtgattg tcagtggcgg gatcgatatt tcgtttggtt cgaccatcgg
     5821 cctctgcgcc attgcattgg gcgtactgtt tcaaagtggt gtgccgatgc cgctggcgat
     5881 actcctgacc ttactgctcg gcgcattgtg cgggctgatc aacgccggat taattatcta
     5941 taccaaagtt aacccgctgg tgattacgct tggcacgctg tatctgtttg ccggaagcgc
     6001 tctgctgctt tccggtatgg ccggagcgac ggggtacgaa ggtattggtg gattcccgat
     6061 ggcgtttaca gatttcgcta acctggatgt gctgggactc cccgttccgc tgattatctt
     6121 cctgatatgt ctcctcgttt tctggctctg gctgcataaa acccatgccg gacgtaatgt
     6181 gtttttgatt gggcaaagcc cgcgcgtggc gctttatagc gcgattccag ttaaccgtac
     6241 cttatgtgcg ctctatgcca tgacggggct ggcgtctgcg gtcgccgctg tgctgctggt
     6301 atcgtatttt ggttcagcac gttccgatct cggtgcgtcg tttctgatgc ccgccatcac
     6361 cgccgtggtg cttggcgggg ccaatattta tggtggttcc ggttccatta tcggcaccgc
     6421 cattgcggtt ttattagtgg gatatttgca acaaggtttg caaatggcag gagtgccaaa
     6481 tcaggtgtcc agcgcccttt ccggtgcgct acttatcgtc gttgtcgtag gtcgttccgt
     6541 tagcctgcat cgccagcaaa ttaaagagtg gctggcgcgt cgggccaata acccattgcc
     6601 ataaaggata tcttcatgac acttcatcgc tttaagaaaa tcgccttact tagcgctctt
     6661 ggcattgccg caatctctat gaatgtgcag gccgcagagc gtattgcatt tattcccaaa
     6721 ctggttggcg tgggattttt taccagcggt ggcaacggcg cacaacaagc gggtaaagag
     6781 ctgggcgttg atgtgaccta cgacgggccg acagaaccca gtgtttctgg tcaggtacag
     6841 ttgattaata acttcgtcaa tcaaggttat aacgccatta tcgtttctgc ggtttcgcct
     6901 gatggcttgt gtccggcact gaaacgcgcc atgcaacgtg gtgtgagagt gctgacctgg
     6961 gactctgata ctaaaccgga gtgccgctct tactacatta atcagggaac gcccgcccag
     7021 ttaggaggta tgttggtgga tatggcggcg cgtcaggtga ataaagacaa agccaaagtc
     7081 gcgtttttct actcaagccc caccgttacg gaccaaaacc agtgggtgaa agaagcgaaa
     7141 gcgaaaatcg ccaaagagca tccaggctgg gaaattgtca ctacgcagtt tggctataac
     7201 gatgccacta aatcgttaca aaccgcagaa ggaatattaa aagcgtatag cgatctcgac
     7261 gccattatcg cccccgatgc caacgccctg cccgctgccg cacaagccgc agaaaacttg
     7321 aaaaatgaca aagtagcgat tgtcggattc agtacgccaa atgtgatgcg cccgtatgta
     7381 gagcgcggca cggtgaaaga atttggcctg tgggatgtgg ttcagcaagg caaaatttca
     7441 gtgtatgtcg cggatgcatt attgaaaaaa ggatcaatga aaacgggcga caagctggat
     7501 atcaagggcg taggtcaggt tgaagtctcg ccaaacagcg ttcagggcta tgactacgaa
     7561 gcggatggta atggcatcgt actgttaccg gagcgcgtga tattcaacaa agagaatatc
     7621 ggcaaatacg atttctgatg tgcattactt aaccggagta agttatggca gatttagacg
     7681 atattaaaga tggtaaagat tttcgtaccg atcaaccgca aaaaaatatc ccttttaccc
     7741 tgaaaggttg cggtgcgctg gattggggaa tgcagtcacg cttatcgcgg atatttaatc
     7801 cgaaaacggg taaaaccgtg atgctggctt ttgaccatgg ttattttcag ggaccgacta
     7861 ccggacttga acgcattgat ataaatatcg ccccgctgtt tgaacatgcc gatgtattaa
     7921 tgtgtacgcg cggcattttg cgcagcgtag ttccccctgc gaccaatagg ccggtggtac
     7981 tgcgggcgtc aggtgcgaac tctattctgg cggaattaag taatgaagcc gtggcgttat
     8041 cgatggatga cgccgtgcgc ctgaacagtt gcgcggtggc ggcgcaggtt tatatcggca
     8101 gcgaatatga acatcagtcg atcaaaaata ttattcagct ggttgatgcc ggaatgaaag
     8161 tgggaatgcc gaccatggcc gtgactggcg tgggcaaaga tatggtgcgc gatcagcgtt
     8221 atttctcgct cgcgactcga atcgccgctg aaatgggggc gcaaattatc aaaacctatt
     8281 atgtcgaaaa aggttttgaa cggattgttg ccggatgtcc ggtacccatt gttattgctg
     8341 gcggtaaaaa attaccggag cgcgaggcgc tggaaatgtg ctggcaggct atcgatcagg
     8401 gcgcttctgg tgtggatatg gggcgtaata ttttccagtc tgaccatccg gtggcgatga
     8461 tgaaagccgt acaggcggtg gttcaccata acgaaacggc tgatcgggca tatgaactct
     8521 atctgagtga aaaacagtaa ctgcggatct aaggagaaga attatgcacg tcacactggt
     8581 tgaaattaac gttcatgaag acaaggttga cgagtttatc gaagtttttc gccagaacca
     8641 cctgggctct gtacaggaag aaggcaattt gcgcttcgat gtcttacagg acccggaagt
     8701 gaattcgcgc ttttatatct acgaagccta taaagatgaa gacgcagtgg cgttccataa
     8761 aaccacgccc cactacaaaa cctgtgtcgc gaaactggaa tctttaatga ccgggccgcg
     8821 taaaaaacgt ctgttcaatg gtttgatgcc gtgaggcgaa tttatcaatt ttatctacaa
     8881 ttggggtaac gcgctgacgg gagtaaaaaa atgtctgact ggaacccctc tttatatcta
     8941 cacttttccg ctgaacgatc gcgtccggcg gtggagctgc ttgccagagt gccgctggaa
     9001 aatgtcgaat atgttgccga tcttggctgt ggcccaggta acagcaccgc ccttctacaa
     9061 caacgttggc ctgcggccag gataacaggc atcgactcgt ctccggcgat gattgctgaa
     9121 gcgcgcagtg ctttgccaga ctgccagttc gtggaagcag acatccgcaa ctggcaaccg
     9181 gtacaggcac tcgatctgat ttttgctaat gcctcactgc aatggctgcc cgaccactac
     9241 gaattgtttc ctcatctggt ttctttactt aatccgcagg gcgtgctggc agtacagatg
     9301 ccagataact ggctggagcc gacccatgtg ctcatgcgcg aagttgcctg ggaacaaaac
     9361 tacccggatc gcgggcgtga gccgttggct ggcgttcatg cttactacga tattttgagc
     9421 gaagccggat gtgaggtcga tatctggcga accacctact atcaccagat gccgtcacac
     9481 caggcgatta tcgattgggt gactgccact ggattacgtc cgtggttaca ggatctgacc
     9541 gagagcgaac agcagctttt tcttaagcgc taccatcaga tgctggaaga gcagtatcca
     9601 ctgcaagaga acggacagat actgctggca tttccgcgtc tgtttattgt tgcccggcgt
     9661 atggagtaaa tatcacgtca gctggtaatg acgatcggga agaatttttg ctggaatttc
     9721 ggcttcatcg ttcatctgta acaggtcaat ttcaatagcg ttgcagatgg catccagtgg
     9781 taaatcattg ttttcagtac cgaacggatc ttccagttct tccgccagac aatccagcga
     9841 aataaaagtg taggaaatca gcacagagat aaaaggcgtc atgtaatgca ggtccacgac
     9901 cagcgcgaac ggcagcatga tacaaaacag ataaacggta cgatgcaaaa tcagggtgta
     9961 ggcaaaggga attggcgtat aggcaatgcg ctcgcatcct gccaggaccg ctgaaatatc
    10021 attaagccga tcgttgaggc taataaacag gatatctgaa agctgtccat tgcggcgctg
    10081 aaccgccaac cattctccca ttattaacaa gatacggtta gctggagagt tcgaagccag
    10141 tacacgctga agatcttcag tcttgagata atgagccagc acttccgcct gtggctgttt
    10201 gcgtaatgtc atgcgtaaac agtgggcgaa agcgatttgc agccgggcaa actcccttac
    10261 acttgccgaa tccggcaatg tcgtttttac ctcgcgcagt aacgaccgtg aggcaatcat
    10321 caactgcccc caaagttttc gcgcttcaac gtaacgggcg tacccggcat tattacgaaa
    10381 accaagaaaa atggcgatgg cgacaccgag aatgctgaac ggtgcgaggg tgaatttgat
    10441 gcccagatgc gtgtaccagg gcagcatgaa aataacagcg atagaaaaga gaaaattgag
    10501 tagtaagcgc gaggatatct tggataatac tgagccgtgc cagacaaaaa tacggcgcag
    10561 ccagtgttgt tgtggacgaa caatcatggt tatcttcagg cgtggaaaag tcgccctatt
    10621 aaacgtgatt acgatcacat tctcaagacg ctacttacaa attacctaca agcttacaac
    10681 attagcaggc gctgcatgtg gcacctgtta atgataaagg catataggat gttgtaacta
    10741 atatggtgga ataagaaacc cggtcgaaac cgggttcaga agtaacggtg ttattagcac
    10801 aacggacgta cagcttcgcg catccctttt tcgagaatcg catccaggtc attagcaacc
    10861 tgctcgacca gaccaggcac ttgcgtcagg tcctgctccc agtggtcttt ttctgccaaa
    10921 acaatcgcta ccagttcctg ggtgccgata acacggtcac gatgctggct ccagagttgc
    10981 tgataacgtt ccagccagtg tgcatcgtcc tgtaccggat atgtttcgcc gttacgctca
    11041 ccacgataga acgcaatcaa tgccgctaat gcgaaagtaa ggcgcgccgg aagtgtgccg
    11101 tttgccttct gccctgccag cagctgtggc aggatgcggg tgcggaactt ggtcataccg
    11161 ttgagcgcga tagacagcag ctgatgctta atgtacgggt tacggaaacg cccggtgact
    11221 gcactggcga aagattccag ttcatcacga ggcaaatcca gtaccggaat aatttcttcg
    11281 tagatagctt tttcaacgaa tgcgcaaatt tcagcatcgt tcatcgcttc acctacggta
    11341 tccagccctg cctggaacgc caccggcacc agcgcggtgt gcgcaccgtt gaggattgcc
    11401 actttgcgtt ctttgtacgg tttaatatcg tcaacaatca gcacgttgag cggatatttg
    11461 tccagacgta gttcagtcgc taaggatttc ggtccctgaa tcacaaacag gtaaaagtgt
    11521 tcagcggtgt cgagaaaacc atcgtgataa cccagttctt cttccagttt agccacttca
    11581 tcgcgcggat aaccggtaac gatacggtcc accagcgtag aacagaagct gttagcctga
    11641 tccagccatt gaataaatgc ttctggcagt gcccactctt gcgcatagcg cagcaccagt
    11701 tcacgcaacg cgtcgccatt gtagtcaatc aactcacacg gaatgatgat ccaaccttta
    11761 tccagcgcac cgttgaaatg gctaaagcgt tcgaacagca gacgggtcag ttttgccgga
    11821 tagcttaccg ctggcgcgtc atcgaattta tcgcccgcat ggtagctgat acccgcttcg
    11881 gtggtgttag agaaaacaaa gcgcatttcc gggttgtgcg ccagtttcag gaattcatcg
    11941 tattcactgt agacgctgat ttcacgatta accgagcgaa tcagacgcgc gtcgctgacc
    12001 gcttccccct tctcattcag gccacggata atggtggtgt acagaccatc ctgcgtgctc
    12061 agtgacggcg ggaatgaagt ttcaatcgga cgaacaacga ccacgccaga attcagatcg
    12121 gtgtgctcat tcaggagatc gatttgccag tcaacaaagg cgcgcaggaa gttaccttca
    12181 ccaaactgaa tgatacgttc tggatactgt gcaccgggaa aatcgcgacg atttagtgtt
    12241 ttcacaatgg gttcccttct gattagtcat acaacctgtt tgaattggta cgacaggtta
    12301 gcaaacttta atacgccgaa cccctgtttt gatcaactcc tgatgattaa tgagcagttt
    12361 tatgagaaaa gtgtggcgcg gatcatggtt taatcgagga aaaacgcctt ttcctggatc
    12421 ataaagtggt agaacacatt gcattcaaat cgcgcgtaat gaataaagat gtcagacaac
    12481 ttcctcaccg taacgcatag tgctggtacg gttgcgccca tctttcttcg agcgatacag
    12541 acacgtatcg gcttcgacca tcaatttatt aaagtcatcg gtcagcgtta ggtacgatgc
    12601 gcgaccacta ccgacgccaa tacttaccgt gagataaagc gttttttgtt gccaggtgaa
    12661 tggttgcagt tcaacgcctt tacggatttt ttccgccatt agcagaccat cgacaggatt
    12721 caccgacggc actgcaacag caaattcttc gccgcccatt cgcgccacca gccccttatc
    12781 accgacaatc ttctgaatat gccgggcaaa cacgcttaac actttatcgc cacattcatg
    12841 tccatagtta tcgttaatgc ttttgaaata gtcgatatca agcagcatga cagtcagatg
    12901 ttgtgtctgt ttcagcgatg gacttttcag cgcctcataa agaccggacc gtgagtaaac
    12961 ctgagtcaga aaatcaaagt cggctcgcag cgcaacttgc ttcattagcg aattgatcgc
    13021 tgccacgcta aaagaaacca taattgggca tatcgccatc gtggcaatac cgagacgtgc
    13081 ggagaacatt tgcggaatgg agaacggcga accgaccgag atatcaatca ccgaatttgc
    13141 caccagtacg atttccaccg caccggtgac aaaggtcaac agacatgtta cctgcggcgt
    13201 atagcgcact gcacaccaga ttaatgcagg cagcgggaac gccagactcc ccgctccgcc
    13261 aatgactacc gaggcaataa ccgacacaat aagcgcgatg gcgggcatca tctgttctgc
    13321 tttaaagcgc ggcagcactc caggaatagc caacgtcagc atacaaggca cgatcaacac
    13381 gcccgttgag aattgctcac tgaaccagtc cgcaagcaaa ggccagaaat ccagactatc
    13441 aatactgacc gaaccaagat agcatgttcg ctgacagcgg cggcaaataa aggtaccctg
    13501 ggaatgctat tttgtcgttt tccgcaattc tcatggctga ttcatctgta caaccagcca
    13561 gtgatagatt accgccacga tataacgttg ttgttcttcg cttaacgaaa caccctgcgg
    13621 aatgttatgc cacttagcca gacaaccgcg acagcaggtc gcggtggcgt gctgagcgat
    13681 aaacaccgga tgcccgcgca tgggggtttg cttaccgtca ttagccggta atgccggagc
    13741 aagacgttta gcgacaaaat ccgccgcatg ttgttcgatg actggcgcgc ctttctccag
    13801 gcaatactga cgctctttca tgcccagacg aaagcgagag cgaaattttg aacgggataa
    13861 acgcgcgaag agtggatcga gagactgcat taataaaccg aacgccctaa ctgtttcgtc
    13921 aattgttcaa ggacggcaat acccgcaagc gagttacctg catcatccag ttccggactc
    13981 cagacagcga tggccatttc atgcggaaca atcgccacaa taccgccacc aacgccagat
    14041 ttcgccggta gccccacccg ccaggcaaac tcccccgcgt tctggtacat accactggtc
    14101 gccatcagcg cgttaatttg ccgcgcctgc attggcgtca ccactggttc atcaatatga
    14161 atagctttcc cctgattagc cagaaagaca aacgtccggg ccagctctac acagctcatt
    14221 ttcagagcgc agtaatgaaa gtagttttgc agaacggttg tcacgtcatg atggaaattg
    14281 ccaaacgact tcatcagcca ggcgatagcc gcatttcgcg cggaatgttc aaattcggaa
    14341 cgcgctacca ccgtatcgta ggaaatatca gacacaccgc ttaagccgcg cacgacttcc
    14401 agcatacgtt gccgtggtgc gcttaatcgc ccttgcaaca tatcgcagac caccagcgca
    14461 ccggcattaa tgaacggatt acgcggtata ccctgctcca tttccagttg cactaaggaa
    14521 ttgaacggtg atccagacgg atctttgccg acgcgttgcc agatttcctc ttcggagtaa
    14581 tgacgcatgg cgacaacgag actcagcact ttggaaatag actgaatgga aaaacgttct
    14641 tgcgcgtctc cggcctgaaa aagctgtccg tcaacggtac agatagcaat ccccaatcgg
    14701 gaaccgtcta ctgtagccag cgccggaata taatccgcga ctttaccctg accaatgagc
    14761 ggccgcactt gccgcaagat gttttctaaa attgcattat ccatggcgac tgccactttc
    14821 tactcctgga ccgcaggtct gaaaagacct gcgagtatat cagagctgaa tatgtcgcgt
    14881 cagatccggt ctttccacac cgtctggata ttacagaatt cgtgtaagcc gaaatgggaa
    14941 agctcacgac caaagccact ctttttcacg ccaccaaagg ccactcgcgc gtcgctggca
    15001 caataaccat tgataaacac cccaccgcat tccagacgtg ccgccatctg tctggcctgt
    15061 gtttcgtcag tggtaaaaat ggtcgctgaa aggccgaact cactatcatt agccagttcc
    15121 agtgcatgtt ctgcatcttt cgcaatggtg attgccgcaa cggggccaaa catttcttcc
    15181 cgaaacgcgg tcatttctgg ggtaacattc gccagaaccg ttggcggata gtagttacct
    15241 gccccagcca tcttttcccc gcccagtaac aaacgcgcac cctgcgccag ggttttctcc
    15301 acctgatgat gcagctcatc acgtaaatca aaacgagcca ttggtccgag agcgttctct
    15361 tcgtcacggg gatcgcccat tttcaaggct gccgcagctg ccacaaaacg ttcggtaaat
    15421 gccgaagcaa ttccctcttc gataataaag cgttttgccg ctgcacatac ctgtccggta
    15481 ttctgataac gtccggctac cgccgctttc accgccagtt ccagatcggc atcgttaagc
    15541 acaataaacg gatccgaacc gcccagttcc agtacgcatt ttttcagtgc cgctccagcc
    15601 tgtgcgccaa tagccgctcc cgcacgaaca cttccggtca ccgtgacagc agcaatgcgc
    15661 gagtctttaa tcatctgact gacaccgtcg ttgtcggcat tcagccagcc atatacgcct
    15721 tgtgggatac ccgcatcttt aaacacctgg gcaatgagct gtgcacagcc catcacattc
    15781 ggcgcatgtt taagtaagta gccgttacct gcaagaatga tgggaacagc gccacgcatc
    15841 acctgccata acggaaaatt ccacggcata atcgccagaa tcgtccccaa cggtcgatac
    15901 tcaataaccg cctgctgatt ttccaccagc gtaggttccg ccttcagcat tgccggacca
    15961 tgttctgcat accagtcaca caaattcgcc gatttcgcca cttcagcgcg cgcctggttg
    16021 attggtttgc ccatttcgcg ggtgatcatt tgcgccattt cttcgctacg agcgcgcaga
    16081 gccttaccga tatcacgcag tttttcagca cgataatcta tatttgtctc gcgccagtcg
    16141 cgaaagcctg ctgccgccag ctgaagtgcg ttttcgatat cgtcagcgcc agcccacggc
    16201 agcacagaaa gttgttcacc cgtggcagga tttatcgaaa ttgcatgagt tgccggagta
    16261 atggtcatcg gggtatctcc tttatgagtc atggtatgaa aatacgcaga tttactcttg
    16321 ctttaaaatg aataatatta agccacttat tcacgaatcg agaatgctat ggatctgacc
    16381 caactggaga tgttcaacgc ggttgccgaa gctggcagca taacccaggc tgcagcaaaa
    16441 gtgcatcgcg tgccgtcgaa tctcactacc cgtctgcgcc agctggaaac agaactgggg
    16501 gttgatctgt ttattcgcga gaatcagcgt ttacgtctct ctcctgccgg gcataacttt
    16561 ttacgctata gccaacaaat tctcgcgtta gtggatgaag cgcggagcgt tgtcgctggc
    16621 gatgagccgc aaggtttatt ttctcttggt tcgctggaaa gcaccgctgc agtgcgcatt
    16681 ccagccacgc tggcggaatt caaccgtcgt tatcccaaaa ttcagttttc actttccacc
    16741 ggcccttccg gcactatgct ggatggtgta ctggagggaa aactgaatgc ggcgtttatt
    16801 gatggaccca ttaaccatac tgccatcgac gggataccgg tataccgcga ggaactgatg
    16861 atcgtcacgc cacaaggata tgcgccagta acccgtgcca gtcaggttaa tggcagtaac
    16921 atttatgcct tccgcgccaa ttgttcgtat cgtcgccact tcgagagctg gtttcatgct
    16981 gacggtgccg ctccgggaac tatccatgag atggagtctt atcacggaat gttggcctgt
    17041 gtgatcgcag gagcaggcat tgcgcttatt ccgcgctcta tgctggaaag tatgccgggg
    17101 catcaccagg ttgaagcgtg gccgttagct gagcaatggc gttggttaac aacctggctg
    17161 gtctggcgtc gtggtgcgaa aacacgtccg ctcgaggcat ttattcaact gctggatgtg
    17221 cctgactcgg caagacaggg atatcaatga gctatttttg atagttcttg cggttaatat
    17281 gctctatata gtgatgttcc gatgacttat gactatatgg ggcaaatatg gttacgccag
    17341 taagcatcag caattacata tctcttcctg atga
//
LOCUS       DAPOAV010000090        17329 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.090, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000090 DAPOAV010000000
VERSION     DAPOAV010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17329
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.090"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            321..407
                     /gene="leuL"
                     /locus_tag="RN951_003528"
     CDS             321..407
                     /gene="leuL"
                     /locus_tag="RN951_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leu operon leader peptide"
                     /protein_id="HDX2528477.1"
                     /translation="MTHIVRFIGLLLLNASSLRGRRVSGIQH"
     gene            500..2071
                     /gene="leuA"
                     /locus_tag="RN951_003529"
     CDS             500..2071
                     /gene="leuA"
                     /locus_tag="RN951_003529"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HDX2528478.1"
                     /translation="MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVME
                     VGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIAT
                     SPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAIN
                     AGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAV
                     HAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQI
                     CNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGR
                     AAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFR
                     LDYFSVQSGSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITEYNVELVKYS
                     LTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKE
                     LQRKAQHNENNKETV"
     gene            2071..3162
                     /gene="leuB"
                     /locus_tag="RN951_003530"
     CDS             2071..3162
                     /gene="leuB"
                     /locus_tag="RN951_003530"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HDX2528479.1"
                     /translation="MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYD
                     VGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHF
                     KLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEK
                     AFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPD
                     VELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQG
                     FGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADDAACAIERAINRALEEGI
                     RTGDLARGAAAVSTDEMGDIIARYVAEGV"
     gene            3165..4565
                     /gene="leuC"
                     /locus_tag="RN951_003531"
     CDS             3165..4565
                     /gene="leuC"
                     /locus_tag="RN951_003531"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HDX2528480.1"
                     /translation="MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGL
                     RAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNH
                     PYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ
                     GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMT
                     LCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTV
                     VTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPL
                     TEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLD
                     KIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMA
                     AAAAVTGHFADIRNIK"
     gene            4576..5181
                     /gene="leuD"
                     /locus_tag="RN951_003532"
     CDS             4576..5181
                     /gene="leuD"
                     /locus_tag="RN951_003532"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HDX2528481.1"
                     /translation="MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLF
                     NDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVI
                     APSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTY
                     RFTIDAFRRHCMMNGLDSIGLTLQHDDAIAAYEAKQPAFMN"
     gene            complement(5230..6408)
                     /gene="setA"
                     /locus_tag="RN951_003533"
     CDS             complement(5230..6408)
                     /gene="setA"
                     /locus_tag="RN951_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter SetA"
                     /protein_id="HDX2528482.1"
                     /translation="MIWIMTMARRMNGVYAAFMLVAFMMGVAGALQAPTLSLFLSREV
                     GAQPFWIGLFYTVNAIAGIGVSLWLAKRSDSQGDRRKLIIFCCLMAIGNALLFAFNRH
                     YLTLITCGVLLASLANTAMPQLFALAREYADNSAREVVMFSSVMRAQLSLAWVIGPPL
                     AFMLALNYGFTVMFSIAAGIFTLSLVLIAFMLPSVARVELPSENALSMQGGWQDSNVR
                     MLFVASTLMWTCNTMYIIDMPLWISSELGLPDKLAGFLMGTAAGLEIPAMILAGYYVK
                     RYGKRRMMVIAVAAGVLFYTGLIFFNSRMALMTLQLFNAVFIGIVAGIGMLWFQDLMP
                     GRAGAATTLFTNSISTGVILAGVIQGAIAQSWGHFAVYWVIAVISVVALFLTAKVKDV
                     "
     gene            complement(6510..6641)
                     /gene="sgrT"
                     /locus_tag="RN951_003534"
     CDS             complement(6510..6641)
                     /gene="sgrT"
                     /locus_tag="RN951_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake inhibitor SgrT"
                     /protein_id="HDX2528483.1"
                     /translation="MRQFYQHYFTATAKLCWLRWLSVPQRLTMLEGLMQWDDRNSES"
     gene            6730..8385
                     /gene="sgrR"
                     /locus_tag="RN951_003535"
     CDS             6730..8385
                     /gene="sgrR"
                     /locus_tag="RN951_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SgrR"
                     /protein_id="HDX2528484.1"
                     /translation="MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLL
                     NTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKAT
                     VRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEE
                     NGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIA
                     DIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRN
                     STNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEG
                     CYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHART
                     IKSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLKIKEIDYDQWHTGEIES
                     DIWLNSANFTLPLDFSVFAHLCEVPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVA
                     SKAMVPLLHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP"
     regulatory      8419..8518
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            8549..9532
                     /gene="thiB"
                     /locus_tag="RN951_003536"
     CDS             8549..9532
                     /gene="thiB"
                     /locus_tag="RN951_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter substrate binding
                     subunit"
                     /protein_id="HDX2528485.1"
                     /translation="MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAF
                     EADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVA
                     ADAVNVPGGWNNDTFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRT
                     STPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTS
                     PAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIP
                     TGNWMYPVANVTLPAGFEKLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR"
     gene            9508..11118
                     /gene="thiP"
                     /locus_tag="RN951_003537"
     CDS             9508..11118
                     /gene="thiP"
                     /locus_tag="RN951_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine/thiamine pyrophosphate ABC transporter
                     permease ThiP"
                     /protein_id="HDX2528486.1"
                     /translation="MATRRQPLIPGWLIPGVSATTLVVAVALAAFLALWWNAPQDDWV
                     AVWQDSYLWHVVRFSFWQAFLSALLSVIPAIFLARALYRRRFPGRLALLRLCAMTLIL
                     PVLVAVFGILSVYGRQGWLATLCQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQ
                     ALENIPGEQRQLAAQLGMRSWHFFRFVEWPWLRRQIPPVAALIFMLCFASFATVLSLG
                     GGPQATTIELAIYQALSYDYDPARAAMLALLQMVCCLGLVLLSQRLSKAIAPGTTLLQ
                     GWRDPDDRLHSRICDTVLIVLALLLLLPPLLAVIVDGVNRQLPEVLAQPVLWQALWTS
                     LRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQVLEMSGMLILAMPGIVLATGFFL
                     LLNNTIGLPQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRL
                     KVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDDFRTLPFYLYQQIGSYRSQDGA
                     VTALILLLLCFLLFTVIEKLPGRNVKTD"
     gene            11102..11800
                     /gene="thiQ"
                     /locus_tag="RN951_003538"
     CDS             11102..11800
                     /gene="thiQ"
                     /locus_tag="RN951_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter ATP-binding protein
                     ThiQ"
                     /protein_id="HDX2528487.1"
                     /translation="MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNL
                     IAGFLTPASGSLTIDGVDHTTMPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKL
                     NAVQQGKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSAL
                     DPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGMTNELL
                     SGKASASALLGITG"
     gene            complement(11914..12678)
                     /locus_tag="RN951_003539"
     CDS             complement(11914..12678)
                     /locus_tag="RN951_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDX2528488.1"
                     /translation="MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAG
                     LGALIGSGELSVWHAWLAGIIGCLMGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTE
                     HALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPPFYFLPGI
                     LAGAAIDIPAGMQSGEFKWLLLATAVFLWVGGWLCWRLWRSGKATDRLSHYLSRGRLL
                     WLTPLISAIGVVALVVLIRHPLMPVYIDILRKVVGV"
     gene            complement(12764..13642)
                     /gene="araC"
                     /locus_tag="RN951_003540"
     CDS             complement(12764..13642)
                     /gene="araC"
                     /locus_tag="RN951_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose operon transcriptional regulator AraC"
                     /protein_id="HDX2528489.1"
                     /translation="MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKG
                     YILNLTIRGQGVVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAREWYHQWVYFRPRA
                     YWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLL
                     LRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQ
                     LGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEF
                     RAGCEEKVNDVAVKLS"
     gene            13981..15681
                     /gene="araB"
                     /locus_tag="RN951_003541"
     CDS             13981..15681
                     /gene="araB"
                     /locus_tag="RN951_003541"
                     /EC_number="2.7.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulokinase"
                     /protein_id="HDX2528490.1"
                     /translation="MAIAIGLDFGSDSVRALAVDCATGEEIATSVEWYPRWQKGQFCD
                     APNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDSTGSTPAPIDADGNVL
                     ALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKI
                     LHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLP
                     PASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCH
                     MGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAG
                     QSAFGDIYAWFGRVLGWPLEQLAAQHPELKTQINASQKQLLPALTEAWAKNPSLDHLP
                     VVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGI
                     AVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIP
                     SAQQKMASAVEKTLQPCSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVATL
                     "
     gene            15692..17194
                     /gene="araA"
                     /locus_tag="RN951_003542"
     CDS             15692..17194
                     /gene="araA"
                     /locus_tag="RN951_003542"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HDX2528491.1"
                     /translation="MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKL
                     PCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQ
                     FHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERI
                     GSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVV
                     NSISDGDVNALVDEYESCYTMTPATQIHGKKRQNVLEAARIELGMKRFLEQGGFHAFT
                     TTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMED
                     YTYHFEKGNDLVLGSHMLEVCPSIAAEEKPILDVQHLGIGGKDDPARLIFNTQTGPAI
                     VASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHH
                     TVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR"
BASE COUNT         4159 a         4759 c         4603 g         3808 t
ORIGIN      
        1 caccaaatca atatcaaaaa aaatcgcaaa acatataatt caatacaaat catcaggata
       61 ggttttgcaa cgcgtgcatt ttgtcccctt tttcctcgtt gattagatgc aaaaatttat
      121 gctgaaatat gtcaaccgat gaaaagcgtc ggtagttaag cagaaattaa tatcgcttac
      181 tttaaccacc gcagcacaat tagctaattt tacggatgca gaactcacgc tggcgggacg
      241 tttttattgc gtcagggttg acatccgttt ttgtatccag taactctaaa agcatatcgc
      301 attcatctgg agctgattta atgactcaca tcgttcgctt tatcggtcta ctactactaa
      361 acgcatcttc tttgcgcggt agacgagtga gcggcatcca gcattaagcc agcacgcagt
      421 caaacaaaaa acccgcgcca ttgcgcgggt ttttttatgc ccgaagcgag gcgctctaaa
      481 agagacaagg acccaaacca tgagccagca agtcattatt ttcgatacca cattgcgcga
      541 cggtgaacag gcgttacagg caagcttgag tgtgaaagaa aaactgcaaa ttgcgctggc
      601 ccttgagcgt atgggtgttg acgtgatgga agtcggtttc cccgtctctt cgccgggcga
      661 ttttgaatcg gtgcaaacca tcgcccgcca ggttaaaaac agccgcgtat gtgcgttagc
      721 tcgctgcgtg gaaaaagata tcgacgtggc ggccgaatcc ctgaaagtcg ccgaagcctt
      781 ccgtattcat acctttattg ccacttcgcc aatgcacatc gccaccaagc tgcgcagcac
      841 gctggacgag gtgatcgaac gcgctatcta tatggtgaaa cgcgcccgta attacaccga
      901 tgatgttgaa ttttcttgcg aagatgccgg gcgtacaccc attgccgatc tggcgcgagt
      961 ggtcgaagcg gcgattaatg ccggtgccac caccatcaac attccggaca ccgtgggcta
     1021 caccatgccg tttgagttcg ccggaatcat cagcggcctg tatgaacgcg tgcctaacat
     1081 cgacaaagcc attatctccg tacataccca cgacgatttg ggcctggcgg tcggaaactc
     1141 actggcggcg gtacatgccg gtgcacgcca ggtggaaggc gcaatgaacg ggatcggcga
     1201 gcgtgccgga aactgttccc tggaagaagt catcatggcg atcaaagttc gtaaggatat
     1261 tctcaacgtc cacaccgcca ttaatcacca ggagatatgg cgcaccagcc agttagttag
     1321 ccagatttgt aatatgccga tcccggcaaa caaagccatt gttggcagcg gcgcattcgc
     1381 acactcctcc ggtatacacc aggatggcgt gctgaaaaac cgcgaaaact acgaaatcat
     1441 gacaccagaa tctattggtc tgaaccaaat ccagctgaat ctgacctctc gttcggggcg
     1501 tgcggcggtg aaacatcgca tggatgagat ggggtataaa gaaagtgaat ataatttaga
     1561 caatttgtac gatgctttcc tgaagctggc ggacaaaaaa ggtcaggtgt ttgattacga
     1621 tctggaggcg ctggccttca tcggtaagca gcaagaagag ccggagcatt tccgtctgga
     1681 ttacttcagc gtgcagtctg gctctaacga tatcgccacc gccgccgtca aactggcctg
     1741 tggcgaagaa gtcaaagcag aagccgccaa cggtaacggt ccggtcgatg ccgtctatca
     1801 ggcaattaac cgcatcactg aatataacgt cgaactggtg aaatacagcc tgaccgccaa
     1861 aggccacggt aaagatgcgc tgggtcaggt ggatatcgtc gctaactaca acggtcgccg
     1921 cttccacggc gtcggcctgg ctaccgatat tgtcgagtca tctgccaaag ccatggtgca
     1981 cgttctgaac aatatctggc gtgccgcaga agtcgaaaaa gagttgcaac gcaaagctca
     2041 acacaacgaa aacaacaagg aaaccgtgtg atgtcgaaga attaccatat tgccgtattg
     2101 ccgggggacg gtattggtcc ggaagtgatg acccaggcgc tgaaagtgct ggatgccgtg
     2161 cgcaaccgct ttgcgatgcg catcaccacc agccattacg atgtaggcgg cgcagccatt
     2221 gataaccacg ggcaaccact gccgcctgcg acggttgaag gttgtgagca agccgatgcc
     2281 gtgctgtttg gctcggtagg cggcccgaag tgggaacatt taccaccaga ccagcaacca
     2341 gaacgcggcg cgctgctgcc tctgcgtaag cacttcaaat tattcagcaa cctgcgcccg
     2401 gcaaaactgt atcaggggct ggaagcattc tgtccgctgc gtgcagacat tgccgcaaac
     2461 ggcttcgaca tcctgtgtgt gcgcgaactg accggcggca tctatttcgg tcagccaaaa
     2521 ggccgcgaag gtagcggaca atatgaaaaa gcctttgata ccgaggtgta tcaccgtttt
     2581 gagatcgaac gtatcgcccg catcgcgttt gaatctgctc gcaagcgtcg ccacaaagtg
     2641 acgtcgatcg ataaagccaa cgtgctgcaa tcctctattt tatggcggga gatcgttaac
     2701 gagatcgcca cggaataccc ggatgtcgaa ctggcgcata tgtacatcga caacgccacc
     2761 atgcagctga ttaaagatcc atcacagttt gacgttctgc tgtgctccaa cctgtttggc
     2821 gacattctgt ctgacgagtg cgcaatgatc actggctcga tggggatgtt gccttccgcc
     2881 agcctgaacg agcaaggttt tggactgtat gaaccggcgg gcggctcggc accagatatc
     2941 gcaggcaaaa acatcgccaa cccgattgca caaatccttt cgctggcact gctgctgcgt
     3001 tacagcctgg atgccgatga tgcggcttgc gccattgaac gcgccattaa ccgcgcatta
     3061 gaagaaggca ttcgcaccgg ggatttagcc cgtggcgctg ccgccgttag taccgatgaa
     3121 atgggcgata tcattgcccg ctatgtagca gaaggggtgt aatcatggct aagacgttat
     3181 acgaaaaatt gttcgacgct cacgttgtgt acgaagccga aaacgaaacc ccactgttat
     3241 atatcgaccg ccacctggtg catgaagtga cctcaccgca ggcgttcgat ggtctgcgcg
     3301 cccacggtcg cccggtacgt cagccgggca aaaccttcgc taccatggat cacaacgtct
     3361 ctacccagac caaagacatt aatgcctgcg gtgaaatggc gcgtatccag atgcaggaac
     3421 tgatcaaaaa ctgcaaagaa tttggcgtcg aactgtatga cctgaatcac ccgtatcagg
     3481 ggatcgtcca cgtaatgggg ccggaacagg gcgtcacctt gccggggatg accattgtct
     3541 gcggcgactc gcataccgcc acccacggcg cgtttggcgc actggccttt ggtatcggca
     3601 cttccgaagt tgaacacgta ctggcaacgc aaaccctgaa acagggccgc gcaaaaacca
     3661 tgaaaattga agtccagggc aaagccgcgc cgggtattac cgcaaaagat atcgtgctgg
     3721 caattatcgg taaaaccggt agcgcaggcg gcaccgggca tgtggtggag ttttgcggcg
     3781 aagcaatccg tgatttaagc atggaaggtc gtatgaccct gtgcaatatg gcaatcgaaa
     3841 tgggcgcaaa agccggtctg gttgcaccgg acgaaaccac ctttaactat gtcaaaggcc
     3901 gtctgcatgc gccgaaaggc aaagatttcg acgacgccgt tgcctactgg aaaaccctgc
     3961 aaaccgacga aggcgcaact ttcgataccg ttgtcactct gcaagcagaa gaaatttcac
     4021 cgcaggtcac ctggggcacc aatcccggcc aggtgatttc cgtgaacgac aatattcccg
     4081 atccggcttc gtttgccgat ccggttgaac gcgcgtcggc agaaaaagcg ctggcctata
     4141 tggggctgaa accgggtatt ccgctgaccg aagtggctat cgacaaagtg tttatcggtt
     4201 cctgtaccaa ctcgcgcatt gaagatttac gcgcggcagc ggagatcgcc aaagggcgaa
     4261 aagtcgcgcc aggcgtgcag gcactggtgg ttcccggctc tggcccggta aaagcccagg
     4321 cggaagcgga aggtctggat aaaatcttta ttgaagccgg ttttgaatgg cgcttgcctg
     4381 gctgctcaat gtgtctggcg atgaacaacg accgtctgaa tccgggcgaa cgttgtgcct
     4441 ccaccagcaa ccgtaacttt gaaggccgcc aggggcgcgg cgggcgcacg catctggtca
     4501 gcccggcaat ggctgccgct gctgctgtga ccggacattt cgccgacatt cgcaacatta
     4561 aataaggagc acaccatggc agagaaattt atcaaacaca caggcctggt ggttccgctg
     4621 gatgccgcca atgtcgatac cgatgcaatc atcccgaaac agtttttgca gaaagtgacc
     4681 cgtacgggtt ttggcgcgca tctgtttaac gactggcgtt ttctggatga aaaaggccaa
     4741 cagccaaacc cggacttcgt gctgaacttc ccgcagtatc agggcgcttc cattttgctg
     4801 gcacgagaaa acttcggctg tggctcttcg cgtgagcacg cgccctgggc attgaccgac
     4861 tacggtttta aagtggtgat tgcgccgagt tttgctgaca tcttctacgg caatagcttt
     4921 aacaaccagc tgctgccggt gaaattaagc gatgcagaag tggacgaact gtttgcgctg
     4981 gtgaaagcta atccggggat ccatttcgac gtggatctgg aagcgcaaga ggtgaaagcg
     5041 ggagagaaaa cctatcgctt taccatcgat gccttccgcc gccactgcat gatgaacggt
     5101 ctggacagta ttgggcttac cttgcagcac gacgacgcca ttgccgctta tgaagcaaaa
     5161 caacctgcgt ttatgaatta atccccttgc ccggtcaaat gaccgggctt tccgctatcg
     5221 tccacgtcat caaacgtctt taacctttgc ggttaaaaat aatgcgacaa cagaaataac
     5281 cgcaattacc cagtagacag caaagtgccc ccaactttgt gcaattgctc cctgaataac
     5341 gccagccaga attaccccgg tagaaatact gttagtaaat aaggtggtag ctgcccccgc
     5401 tcttccaggc attaaatcct gaaaccatag catcccaata cccgcaacaa tgccgataaa
     5461 tacagcgtta aaaagttgca gcgtcatcaa cgccatacgg ctattaaaga aaatcaatcc
     5521 ggtgtaaaac agtactcctg ccgccactgc tatgaccatc attcgccgct taccataacg
     5581 tttgacatag tagccagcca gaatcattgc tggtatttcc agtccagctg ccgtccccat
     5641 caggaaaccc gccagtttgt ctggcaatcc taactcgcta ctgatccaca acggcatatc
     5701 aataatgtac atggtgttgc aggtccacat taacgtcgag gcgacaaata acatccgtac
     5761 gttactatcc tgccagccac cttgcattga taaagcattt tccgacggca gttctacccg
     5821 cgccacagac ggaagcataa atgcaatcaa taccagactg agtgtgaata tcccggcggc
     5881 aatcgaaaac atcaccgtaa agccgtaatt caacgccagc ataaaggcca acggtggacc
     5941 gataacccat gccagagaaa gctgcgcacg catcaccgag ctaaacatca ccacttctcg
     6001 cgccgagtta tccgcatatt cccgcgccag agcaaataac tgtggcattg ccgtattggc
     6061 cagagatgcc agaagcacac cacaggtgat aagcgtcaga taatgacgat taaatgcaaa
     6121 caatagcgca ttgccgatag ccatcaaaca gcaaaatata atcagttttc gccgatcgcc
     6181 ctgactgtca gaacgttttg ccaaccagag gcttacgccg atcccagcaa tagcattcac
     6241 cgtataaaag aggccgatcc agaaaggttg cgcgccaacc tcacgactca gaaataagct
     6301 caatgtagga gcctgtagcg ccccggccac ccccatcata aaagcgacca gcataaatgc
     6361 cgcgtaaaca ccgttcatac ggcgagccat cgtcattatc cagatcatac gttccctttt
     6421 tagcgcggcg agaataaaaa aaaccagcag gtataatctg ctggcgggtg attttacacc
     6481 aatactcagt cacacatgat gcaggcaagt caactttcag aattgcggtc atcccactgc
     6541 atcagtcctt caagcatggt taatcgttgt gggacgctta accaacgcaa ccagcacaac
     6601 ttcgctgtcg cggtaaaata gtgctgataa aactgacgca tggggcaccc ccttgcttca
     6661 tcgttaggaa ttattgactt aatataggga aaataaaatt gctgtctttt gcacaggagt
     6721 tcccctttta tgccatctgc tcgtctgcaa caacagttca tccgcctgtg gcaatgctgc
     6781 gagggtaaat cgcaggacac aacgctcaac gaactggcag cgttattgag ctgctcgcgt
     6841 cgtcatatgc gcaccctgct caacaccatg caggatcgcg gctggctgac gtgggaagcg
     6901 gaagtcgggc gcggtaaacg ctcgcgtctg acattcctct ataccgggct ggcgcttcag
     6961 caacagcggg cggaagacct gctggagcag gatcgtatcg atcaactggt gcagttggtt
     7021 ggcgacaaag cgactgtgcg gcaaatgctg gtttctcatc tgggccgcag cttccgccag
     7081 gggcggcaca tcctgcgcgt gctctactat cgtccgttgc gtaatctgct acctggcagc
     7141 gcattgcgcc gttccgaaac ccatatcgcc cggcaaatct tcagttcgct aacgcgcata
     7201 aatgaggaaa atggggaact ggaagcagac atcgcccacc actggcagca aatttcaccg
     7261 cttcactggc gtttcttttt gcgtccagga gtccattttc accatggtcg tgaactggaa
     7321 atggacgatg tgatcgcctc tttaaaacga atcaatacgc tgccgctcta ttcgcatatt
     7381 gctgacattg tgtcgccgac gccctggacg ctggatatcc atctcacgca accggaccgc
     7441 tggttaccgt tactgctggg gcaagttccg gcgatgatcc tgccgcgcga atgggaaacc
     7501 ctcagtaact ttgccagcca tcccatcggc accggtccgt atgcggtgat tcgcaacagc
     7561 accaatcaac tgaaaattca ggcattcgat gacttcttcg gttaccgggc attaatcgac
     7621 gaagttaacg tctgggttct gccggaaatt gccgacgagc cagccggagg gctgatgcta
     7681 aaaggtccac agggcgagga aaaagagatt gaaagccgcc tggaggaagg ttgctactat
     7741 ttactgttcg acagccgcac ccatcgcggg gcgaatcagc aagtcaggga ctgggtaagc
     7801 tatgtgcttt ctccaactaa tctggtctat ttcgctgagg aacagtacca gcaactgtgg
     7861 ttcccggctt atggactgct cccccgttgg caccatgccc gcaccataaa gagcgaaaaa
     7921 ccggctggcc tggaaagcct caccctaacc ttttatcagg atcacagtga gcatcgggtg
     7981 attgccggga tcatgcagca gattctggca agtcaccagg tcacgctgaa aatcaaagag
     8041 atcgactacg atcagtggca tacaggagag atcgaaagtg atatctggct aaacagcgcc
     8101 aactttaccc tgccgctgga cttctctgtt ttcgcacatt tatgcgaagt gccactgcta
     8161 caacattgca ttcccattga ctggcaagcc gacgctgctc gctggcgcaa tggcgagatg
     8221 aatctggcga actggtgcca gcaactggtc gccagcaaag cgatggtgcc attattgcac
     8281 cactggctga tcattcaggg gcaacgcagt atgcgcggcc tgcgcatgaa taccctcggc
     8341 tggttcgatt ttaaatcagc gtggtttgcg ccaccggatc catgattgct ggttgataac
     8401 aaaatcacta cactaacgcc gttctcaacg gggtgccacg cgtacgcgtg cgctgagaaa
     8461 atacccgtcg aacctgatcc ggataacgcc ggcgaaggga tttgaggctc cttctcaagt
     8521 cctttgccac tcttttttga ggtgcaaagt gttaaaaaaa tgtctgcccc tgctgttgct
     8581 gtgcacagcg cccgttttcg ctaaacccgt tctgactgtt tatacctacg attccttcgc
     8641 cgccgactgg gggcctggtc cggtggttaa aaaagccttt gaagccgact gtaattgcga
     8701 actgaaactg gtggcgctgg aagatggcgt ttcgcttctc aaccgtctac ggatggaagg
     8761 caaaaacagt aaagccgatg tggtgctggg gctggataac aacctgttag acgccgccag
     8821 taaaaccgga ctgtttgcca aaagcggtgt ggcagcggat gccgttaacg ttcccggcgg
     8881 ctggaataat gacactttcg taccgtttga ttatggctac ttcgccttcg tttatgacaa
     8941 gaacaaactg aaaaacccgc cacaaagcct gaaagaactg gttgagagcg atcaaaactg
     9001 gcgggtgatt tatcaggatc cgcgcaccag tacaccgggg ctgggtctgt tgctatggat
     9061 gcaaaaagtc tatggcgatg acgccccaca agcctggcag aaactggcga agaaaacggt
     9121 cacggtcacc aaaggctgga gcgaagccta cggcctgttt ttaaaaggtg aaagcgatct
     9181 ggtactgagt tacaccacct ctccggctta tcacattctc gaagagaaga aagataacta
     9241 cgccgccgcg aacttcagcg aaggtcacta tctgcaagtg gaagtcgccg cccgcaccgc
     9301 tgccagcaag cagccggagc tggcgcaaaa attcctccag tttatggttt ctccggcttt
     9361 ccagaatgcg atcccaaccg gcaactggat gtatccggtg gcaaacgtca cgctgcctgc
     9421 cggttttgaa aaattgacca aacccgcaac cacgttggag ttcacgccag ccgaagtggc
     9481 ggcacaacgt caggcatgga ttagcgaatg gcaacgcgcc gtcagccgtt aattcccggc
     9541 tggttaattc caggtgtaag cgccaccacg ctggtggtag cggttgcgct ggcggcgttt
     9601 ctcgccctgt ggtggaacgc gccgcaggat gactgggtgg cagtctggca ggacagctat
     9661 ctgtggcatg tggtgcgctt ctccttctgg caggcgtttc tctcggcact gctctctgtc
     9721 atacccgcga tattcctcgc ccgcgcgctc tatcgcaggc gctttccggg tcggctggcg
     9781 ctgttgcgtc tgtgtgcaat gaccttgatc ctcccggtgt tggtcgctgt tttcggcatt
     9841 cttagcgtct atggtcgcca gggctggctg gcaacactct gccaatcgct cggtctggag
     9901 tggacctttt cgccctacgg cctgcaaggt attttgctgg cccatgtgtt ttttaatctg
     9961 ccgatggcga gccgcttatt actccaggca ctggaaaaca tccccggcga acagcgtcaa
    10021 cttgccgccc agcttgggat gcgtagctgg cattttttcc gcttcgtcga atggccgtgg
    10081 ttacggcgac aaatcccgcc ggttgctgcg cttatcttta tgctctgttt cgccagcttc
    10141 gccaccgtgc tatcgctggg gggcggtccg caggcgacca ctatcgagct ggcaatctat
    10201 caggcgctga gttacgacta cgatcctgcc cgcgcggcaa tgctggcgct gctccagatg
    10261 gtgtgctgcc tcgggctggt gctgttgagt cagcgattga gtaaggccat tgcgcccggc
    10321 accacgctgc tgcaaggctg gcgcgacccg gacgatcgtc tgcatagccg catttgcgac
    10381 acggtgttaa ttgtgctggc gctgctgctg ttgctgccac cgttactggc ggtgatcgtc
    10441 gatggggtaa atcgccagtt gccggaagtg ctggcacaac cggtgctgtg gcaggcgctg
    10501 tggacctcgt tgcgtattgc gctggcggca ggtgtattgt gcgtagtgct gaccatgatg
    10561 ctgctatgga gcagtcgcga actgcgggcg cggcagaaaa tgctggcggg tcaggtgctg
    10621 gagatgagcg gcatgttgat cctcgccatg ccggggattg tgctggctac cggcttcttt
    10681 ttactgctca acaacactat cggcctgcca caatctgctg acggcattgt gattttcacc
    10741 aatgcgttaa tggcgatccc ttatgcgctg aaagtgctgg aaaacccgat gcgcgatatc
    10801 accgcccgct acagcatgtt atgtcagtcg ctggggattg aaggctggtc acgcttaaaa
    10861 gtggtggagc tgcgcgccct gaaacgtcca ctggcgcagg cgctggcctt tgcatgcgtg
    10921 ctgtcgattg gtgattttgg cgtggtggcg ttgttcggta acgatgattt ccgcaccctg
    10981 ccgttttatc tctaccagca aattggctcc tatcgcagcc aggacggtgc ggtcaccgcg
    11041 ttaattctgc tgctgctctg ttttctgctg tttaccgtga ttgaaaaact accggggcga
    11101 aatgttaaaa ctgactgata tcacctggct ttaccaccat ttgccgatgc gttttagctt
    11161 aacggtggaa cgcggcgagc aggtggcgat cctcgggcca agcggcgcgg gtaaaagtac
    11221 cctgctgaat ttgatcgccg gttttctgac gccagccagc ggttcgctga ctatcgatgg
    11281 cgtagatcac acaactatgc cgccgtcacg ccgtccggtg tcgatgctgt ttcaggagaa
    11341 caacctgttc agccacctga cggtcgcaca gaacatcggg ctggggctaa atccgggatt
    11401 gaaactgaac gcggtacagc aggggaaaat gcacgctatc gcccgccaga tggggattga
    11461 taatttaatg gcgcggttac cgggcgagct ttccggcggt cagcgacagc gagtggcgtt
    11521 agcgcgttgt ctggtacgcg aacagccgat tttattgctc gatgaaccgt tctctgcgct
    11581 cgatccggcg ttacgtcagg agatgttgac gctggtgagc acgagctgcc agcagcaaaa
    11641 aatgacgcta ttgatggtgt cgcacagcgt ggaagatgcg gcgcggatcg ccacgcgctc
    11701 ggtagtagtc gccgacgggc gcatcgcctg gcagggtatg accaatgagt tgttgagcgg
    11761 taaggcgagt gcttcggcac tattggggat tacgggttag tatgcactgt cggatgcggc
    11821 gtgaacgcct tatccgacct acgggtagtg cgttttgtag gcctgataag acgcggcaag
    11881 cgtcgcatca ggcaacccgc acaagactat ctcctaaacc ccaaccactt tacgcaaaat
    11941 atcgatatac accggcatca acgggtggcg aattaacacc accagcgcca ccacgccgat
    12001 ggcagaaatc aacggcgtca gccacaacaa acgaccgcgg gacaaataat gactcaaacg
    12061 gtcagtcgct ttaccgctgc gccataaccg ccagcacagc cagccaccaa cccacaaaaa
    12121 caccgctgtt gccagcagca accatttaaa ctcaccgctc tgcattccgg caggaatatc
    12181 gatcgccgcg cccgccagaa tccctggcag gaagtaaaac ggcggccaca gcaggcagcc
    12241 gataatattc ggcgtaataa atttagccac cggcagatcc agcattcccg ccaccattgg
    12301 caccagcgga cgcgtcgggc caacaaaacg accgaccaga atggtgaaca tgctgtgttg
    12361 atgcaacgca tgttcagttt tatcaagtag tgctttgttt ttcttcagaa atgaccagcg
    12421 atgcaacggc tttttaaaac gccaacccag ccagaaagaa atccagtcgc ccatcaagca
    12481 gccaataatc cctgccagcc aggcgtgcca gacacttaac tcgccgctgc caatcagcgc
    12541 tcccagcccc gccatcagca ccgtaccggg tagaatcaaa ccgaccagcg ccagcgactc
    12601 cagaaaggcc accaacacca ccgccatcaa tgaatacacg gtggattggg taataaagtg
    12661 ttccagcaat gcttgcataa tgtgcctgtc aaatggacga agcagggatt ctgcaaaccc
    12721 tatgctactc cgtcaagccg tcaattgtct gattcgttac caattatgac aacttgacgg
    12781 ctacatcatt cactttttct tcacaaccgg cacgaaactc gctcgggctg gccccggtgc
    12841 attttttaaa tactcgcgag aaatagagtt gatcgtcaaa accaacattg cgaccgacgg
    12901 tggcgatagg catccgggta gtgctcaaaa gcagcttcgc ctgactaatg cgttggtcct
    12961 cgcgccagct taagacgcta atccctaact gctggcggaa aagatgtgac agacgcgacg
    13021 gcgacaagca aacatgctgt gcgacgctgg cgatatcaaa attgctgtct gccaggtgat
    13081 cgctgatgta ctgacaagcc tcgcgtaccc gattatccat cggtggatgg agcgactcgt
    13141 taatcgcttc catgcgccgc agtaacaatt gctcaagcag atttatcgcc agcagctccg
    13201 aatagcgccc ttccccttgc ccggcgttaa tgatttgccc aaacaggtcg ctgaaatgcg
    13261 gctggtgcgc ttcatccggg cgaaagaaac ccgtattggc aaatattgac ggccagttaa
    13321 gccattcatg ccagtaggcg cgcggacgaa agtaaaccca ctggtgatac cattcgcgag
    13381 cctccggatg acgaccgtag tgatgaatct ctcctggcgg gaacagcaaa atatcacccg
    13441 gtcggcagac aaattctcgt ccctgatttt tcaccacccc ctgaccgcga atggtgagat
    13501 tgagaatata acctttcatt cccagcggtc ggtcgataaa aaaatcgaga taaccgttgg
    13561 cctcaatcgg cgttaaaccc gccaccagat gggcgttaaa cgagtatccc ggcagcaggg
    13621 gatcattttg cgcttcagcc atacttttca tactcccacc attcagagaa gaaaccaatt
    13681 gtccatattg catcagacat tgccgtcact gcgtctttta ctggctcttc tcgctaaccc
    13741 aaccggtaac cccgcttatt aaaagcattc tgtaacaaag cggggccaaa gccatgacaa
    13801 aaacgcgtaa caaaagtgtc tataatcacg gcagaaaagt ccacattgat tatttgcacg
    13861 gcgtcacact ttgctatgcc atagcatttt tatccataag attagcggat cctacctgac
    13921 gctttttatc gcaactctct actgtttctc catacccgtt tttttggatg gagtgaaacg
    13981 atggcgattg caattggcct cgattttggc agtgattctg tgcgagcttt ggcggtggac
    14041 tgcgctaccg gtgaagagat cgccaccagc gtagagtggt atccccgttg gcagaaaggg
    14101 caattttgtg atgccccgaa taaccagttc cgtcatcatc cgcgtgacta cattgagtca
    14161 atggaagcgg cactgaaaac cgtgcttgca gagcttagcg tcgaacagcg cgcagctgtg
    14221 gtcgggattg gcgttgacag taccggctcg acgcccgcac cgattgatgc cgacggaaac
    14281 gtgctggcgc tgcgcccgga gtttgccgaa aacccgaacg cgatgttcgt attgtggaaa
    14341 gaccacactg cggttgaaga agcggaagag attacccgtt tgtgccacgc gccgggcaac
    14401 gttgactact cccgctacat tggtggtatt tattccagcg aatggttctg ggcaaaaatc
    14461 ctgcatgtga ctcgccagga cagcgccgtg gcgcaatctg ccgcatcgtg gattgagctg
    14521 tgcgactggg tgccagctct gctttccggt accacccgcc cgcaggatat tcgtcgcgga
    14581 cgttgcagcg ccgggcataa atctctgtgg cacgaaagct ggggcggcct gccgccagcc
    14641 agtttctttg atgagctgga cccgatcctc aatcgccatt tgccttcccc gctgttcact
    14701 gacacttgga ctgccgatat tccggtgggc accttatgcc cggaatgggc gcagcgtctc
    14761 ggcctgcctg aaagcgtggt gatttccggc ggcgcgtttg actgccatat gggcgcagtt
    14821 ggcgcaggcg cacagcctaa cgcactggta aaagttatcg gtacttccac ctgcgacatt
    14881 ctgattgccg acaaacagag cgttggcgag cgggcagtta aaggtatttg cggtcaggtt
    14941 gatggcagcg tggtgcctgg atttatcggt ctggaagcag gccaatcggc gtttggtgat
    15001 atctacgcct ggtttggtcg cgtactcggc tggccgctgg aacagcttgc cgcccagcat
    15061 ccggaactga aaacgcaaat caacgccagc cagaaacaac tgcttccggc gctgaccgaa
    15121 gcatgggcca aaaatccgtc tctggatcac ctgccggtgg tgctcgactg gtttaacggc
    15181 cgccgcacac cgaacgctaa ccaacgcctg aaaggggtga ttaccgatct taacctcgct
    15241 accgacgctc cgctgctgtt cggcggtttg attgctgcca ccgcctttgg cgcacgcgca
    15301 atcatggagt gctttaccga tcaggggatc gccgttaata acgtgatggc actgggcggc
    15361 atcgcgcgga aaaaccaggt cattatgcag gcctgctgcg acgtgctgaa tcgcccgctg
    15421 caaattgttg cctctgacca gtgctgtgcg ctcggtgcgg cgatttttgc tgccgtcgcc
    15481 gcgaaagtgc acgcagacat cccatcagct cagcaaaaaa tggccagtgc ggtagagaaa
    15541 accctgcaac cgtgcagcga gcaggcacaa cgctttgaac agctttatcg ccgctatcag
    15601 caatgggcga tgagcgccga acaacactat cttccaactt ccgccccggc acaggctgcc
    15661 caggccgttg cgactctata aggacacgat aatgacgatt tttgataatt atgaagtgtg
    15721 gtttgtcatt ggcagccagc atctgtatgg cccggaaacc ctgcgtcagg tcacccaaca
    15781 tgccgagcac gtcgttaatg cgctgaatac ggaagcgaaa ctgccctgca aactggtgtt
    15841 gaaaccgctg ggcaccacgc cggatgaaat caccgctatt tgccgcgacg cgaattacga
    15901 cgatcgttgc gctggtctgg tggtgtggct gcacaccttc tccccggcca aaatgtggat
    15961 caacggcctg accatgctca acaaaccgtt gctgcaattc cacacccagt tcaacgcggc
    16021 gctgccgtgg gacagtatcg atatggactt tatgaacctg aaccagactg cacatggcgg
    16081 tcgcgagttc ggcttcattg gcgcgcgtat gcgtcagcaa catgccgtgg ttaccggtca
    16141 ctggcaggat aaacaagccc atgagcgtat cggctcctgg atgcgtcagg cggtctctaa
    16201 acaggatacc cgtcatctga aagtctgccg atttggcgat aacatgcgtg aagtggcggt
    16261 caccgatggc gataaagttg ccgcacagat caagttcggt ttctccgtca atacctgggc
    16321 ggttggcgat ctggtgcagg tggtgaactc catcagcgac ggcgatgtta acgcgctggt
    16381 cgatgagtac gaaagctgct acaccatgac gcctgccaca caaatccacg gcaaaaaacg
    16441 acagaacgtg ctggaagcgg cgcgtattga gctggggatg aagcgtttcc tggaacaagg
    16501 tggcttccac gcgttcacca ccacctttga agatttgcac ggtctgaaac agcttcctgg
    16561 tctggccgta cagcgtctga tgcagcaggg ttacggcttt gcgggcgaag gcgactggaa
    16621 aactgccgcc ctgcttcgca tcatgaaggt gatgtcaacc ggtctgcagg gcggcacctc
    16681 ctttatggag gactacacct atcacttcga gaaaggtaat gacctggtgc tcggctccca
    16741 tatgctggaa gtctgcccgt cgatcgccgc agaagagaaa ccgatcctcg acgttcagca
    16801 tctcggtatt ggtggtaagg acgatcctgc ccgcctgatc ttcaataccc aaaccggccc
    16861 agcgattgtc gccagcttga ttgatctcgg cgatcgttac cgtctactgg ttaactgcat
    16921 cgacacggtg aaaacaccgc actccctgcc gaaactgccg gtggcgaatg cgctgtggaa
    16981 agcgcaaccg gatctgccaa ctgcttccga agcgtggatc ctcgctggtg gcgcgcacca
    17041 taccgtcttc agccatgcac tgaacctcaa cgatatgcgc caattcgccg agatgcacga
    17101 cattgaaatc acggtgattg ataacgacac acgcctgcca gcgtttaaag acgcgctgcg
    17161 ctggaacgaa gtgtattacg ggtttcgtcg ctaagtagcc gcatccggta tgtaacgcct
    17221 gatgcgacgc tgacgcgtct tatctggcct acacgctgcg attttgtagg ccggataagc
    17281 aaagcgcatc cggcattcaa cgcctgatgc gacgctggcg cgtcttatc
//
LOCUS       DAPOAV010000091        17093 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.091, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000091 DAPOAV010000000
VERSION     DAPOAV010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17093
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.091"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(245..808)
                     /locus_tag="RN951_003543"
     CDS             complement(245..808)
                     /locus_tag="RN951_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDX2528492.1"
                     /translation="MHSQLRERIRLMRARLDNAAPVAEIRAESQLFVSPAPICDRLVT
                     LAEISNRDHILEPSAGTGAILRAIRDTAPEAMCDAVEINSGLVRYLRENFNGVRVQCG
                     DFMEWQSVQYYSRIIMNPPFSHGQDIRHILRAFSLLRPGGVLVAVCLNGPRQQEKLLP
                     FSDVREELPRGTFAYTDVPTMIIRLRA"
     gene            complement(855..2216)
                     /locus_tag="RN951_003544"
     CDS             complement(855..2216)
                     /locus_tag="RN951_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3560 domain-containing protein"
                     /protein_id="HDX2528493.1"
                     /translation="MTLAAITMTAPEAASPVQMYRATYSPDDNKLRLYAASRLDPETY
                     KKVHDAGFRWAPRQALFVAPAWTPGREDVLLSLAGEIEDEDSTLAERQEARAERFTGY
                     SGKRASESAQALDEVERLAAMIPPGQPILVGHHSERRARRDAQRIENGMKRAVMLFER
                     AEYWEERARSALLHAKYKERPDVRWRRIKKIEADLRKAEKTIAQSQKYLTMWRAESLD
                     LNMAKLISSHDHISACFPLDTYPRPAEKSQYEGSRSLWSALDDDIITTEQAREIAIRC
                     HERQIQHQQRWVNHYQNRLIYERAMLDESGGVVTRTQDFEPGGQVFSRGEWLTIIRVN
                     KSNGAVSSVTTPNYSFLGYSGTMKVTPDRITDYKAPSAEEAAVASQAAKRPPVVNYPG
                     EGFREMTKAQWAALPRDCKAVRSVEEAEDHGAYRYRRTMDNNFRLVNVYITDMKITEI
                     PQK"
     gene            complement(2268..2498)
                     /locus_tag="RN951_003545"
     CDS             complement(2268..2498)
                     /locus_tag="RN951_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528494.1"
                     /translation="MTVSIVSPSAAAVKPRRHPRFRREDIPAPEIDPVLKAFGRHIAR
                     SFHRGRGVHIPAMKNTAFGQVLRTLELKRAFN"
     gene            3898..5565
                     /gene="ltrA"
                     /locus_tag="RN951_003546"
     CDS             3898..5565
                     /gene="ltrA"
                     /locus_tag="RN951_003546"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDX2528495.1"
                     /translation="MNTHISVSTIPHPTGWHTIDWKACHARVRKLQLRIAKATRQQQW
                     RQVRELQRILTRSFSGKAVAVRRVTENTGKRTPGIDGKIWHTPKEKWEGICSLNLCGY
                     RPQPLRRIHIPKSNGKTRPLGIPTMRDRAMQALWLLALEPVSETTADHNSYGFRPMRS
                     THDAIESIFLRMSQKVSPKWILEGDIKGCFDNISHDWLLSHIPMDRRLLKKWLKAGYM
                     ERGVFNHTNSGTPQGGIISPVLANMALDGLEKELMQTFRKSGYHSAKHQVNYVRYADD
                     FICSGSSRELLENEVRPLIAAFMRERGLELSEEKTAITHIDKGFDFLGQNVRKYNGKM
                     LIKPSKKNLKNFLCKVREIIKRNPTLPAWKLIGQLNPVIRGWATYHRHVVAKETFNYV
                     DTQIWRAIWRWCVRRHPRKGLRWIAGRYFSFEGRRWIFKAITPEGKILTLFRAMETPI
                     KRHIKIKGEATPYTPGMEIYFERRLDLIWKGKSKKMKTVVQLWKRQGKHCPQCGQPIT
                     NQTGWNIHHRIRKVMGGSDELTNLELLHPNCHRQLHSREAGAHRKHL"
     gene            complement(5879..6070)
                     /locus_tag="RN951_003547"
     CDS             complement(5879..6070)
                     /locus_tag="RN951_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528496.1"
                     /translation="MNISTETRGILRNYRAVINARRREMGQKPLTTAQIVDEICDFVV
                     NQQAVFLGGHYILQGSRNR"
     gene            complement(6067..6489)
                     /locus_tag="RN951_003548"
     CDS             complement(6067..6489)
                     /locus_tag="RN951_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 family protein"
                     /protein_id="HDX2528497.1"
                     /translation="MYCTVKEIIRDVLDTDVPDSECVFAVVLTRGDVRHIAQDWNLSD
                     DELETVMQRLDDAFEHGADVSVVHGVVRELMEEKRASRQVTVPAVMLEKVMALAGSEM
                     KRLYAVGSENGGDGDAFVREEREAMDVVLQALDGETMS"
     gene            complement(6536..6838)
                     /locus_tag="RN951_003549"
     CDS             complement(6536..6838)
                     /locus_tag="RN951_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HDX2528498.1"
                     /translation="MMPEYQGGFWHFIRLPDGGGYMMPDGDRFHMVNGANWFDRTVSA
                     DAAGIILTSLVINRQLWLYHDSGDAGLTQLYRMRDAQLWRHIEFHPECNAIYAALD"
     gene            complement(7321..8091)
                     /locus_tag="RN951_003550"
     CDS             complement(7321..8091)
                     /locus_tag="RN951_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528499.1"
                     /translation="MNETLNALICRHARNLLLAQGWPEETDVDQRNPNHPGWISIYVR
                     LDAPRLATLLINRHGGVLPPHLASAIQKLTGTGAELVLSGSQWQSLPVLPADGTQVSF
                     PYAGEWLAEDEIRAVLAAVRDAIRSICYQVADDARRIRAALTTTGQTLLTRQTRRFRL
                     VVKESDHPCWLDEDDENLPVVLDAIVNRGARFSSVEMYLVSDCIEHILSSGLACDVLR
                     IPDEPPRRWFDRGVLREVVREARVEIRSMADALAKIRD"
     gene            complement(8136..8570)
                     /locus_tag="RN951_003551"
     CDS             complement(8136..8570)
                     /locus_tag="RN951_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001562898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 domain-containing protein"
                     /protein_id="HDX2528500.1"
                     /translation="MYGTCETLCRELEAKYPGDTPLMLVIWSPEEIQALADGMEISLT
                     DHEIRAVLARMEDIPEDQRTESGISSAAVMEIISNVSENRQVTVPAELLASLIQTAEQ
                     ALWKREWAARDNGLVVPECVTRRQAVVNQARALLKNNTREND"
     gene            complement(8583..8804)
                     /locus_tag="RN951_003552"
     CDS             complement(8583..8804)
                     /locus_tag="RN951_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528501.1"
                     /translation="MNYAGHENLRAEVAEVANAMCDLRARLNDMEHRCRFDSDVLVER
                     LARQTLYRANRLFMEAYTEILELDACFKD"
     gene            complement(8805..9488)
                     /locus_tag="RN951_003553"
     CDS             complement(8805..9488)
                     /locus_tag="RN951_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methylase"
                     /protein_id="HDX2528502.1"
                     /translation="MSRFILGDCVRVMATIPDNAIDFILTDPPYLVGFRDRSGRTIAG
                     DVNDDWLQPASNEMYRVLKKDALMVSFYGWNRIDRFMAAWKRAGFSVVGHLVFTKSYT
                     SKSAYVAYRHECAYILAKGRPALPPKPLPDVLGWKYSGNRHHPTEKPVTSLQPLIESF
                     THPNAIVLDPFAGSGSTCVAALQSGRRYIGIELLEQYHRAGQQRLATVQRAMQQGAAN
                     DNWFEPEAA"
     gene            complement(9565..9873)
                     /locus_tag="RN951_003554"
     CDS             complement(9565..9873)
                     /locus_tag="RN951_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002430945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528503.1"
                     /translation="MVCFGLFLGFIWRVTKDVAVLLFLLRRLTRRGRNAACGQCPASG
                     RARDGRFYRSWLASVTVYASLSPFSDECPSSRFRGISSPSERRRLRYSTVGLTRYRTR
                     "
     gene            10005..10967
                     /gene="parM/stbA"
                     /locus_tag="RN951_003555"
     CDS             10005..10967
                     /gene="parM/stbA"
                     /locus_tag="RN951_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid segregation protein ParM"
                     /protein_id="HDX2528504.1"
                     /translation="MLVFIDDGSTNIKLQWQENDGTIKQHISPNSFKREWAVSFGDKK
                     VFNYTLNGEQYSFDPISPDAVVTTNIAWQYSDVNVVAVHHALLTSGLPVSEVDIVCTL
                     PLTEYYDRNNQPNTENIERKKANFRKKITLNGGDTFTIKDVKVMPESIPAGYEVLQEL
                     DELDSLLIIDLGGTTLDISQVMGKLSGISKIYGDSSLGVSLVTSAVKDALSLARTKGS
                     SYLADDIIIHRKDNNYLKQRINDENKISIVTEAMNEALRKLEQRVLNTLNEFSGYTHV
                     MVIGGGAELICDAVKKHTQIRDERFFKTNNSQYDLVNGMYLIGN"
     gene            10970..11320
                     /locus_tag="RN951_003556"
     CDS             10970..11320
                     /locus_tag="RN951_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001630992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid partitioning/stability family protein"
                     /protein_id="HDX2528505.1"
                     /translation="MDKRRTIAFKLNPDVNQTDKIVCETLDSIPQGERSRLNRAALTA
                     GLALYRQDPRAPFLLCELLTKETTFSDIVNILRSLFPKEMADFNSSIVTQSSSQQEQK
                     SDEETKKNAMKLIN"
     gene            11429..11891
                     /locus_tag="RN951_003557"
                     /pseudo
     CDS             11429..11891
                     /locus_tag="RN951_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(12116..13117)
                     /locus_tag="RN951_003558"
     CDS             complement(12116..13117)
                     /locus_tag="RN951_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4238 domain-containing protein"
                     /protein_id="HDX2528506.1"
                     /translation="MTEPLNLRTDVVRQHTVPRFLLKHFSKPVKGKRQRLHAFDKAAG
                     RAYATTPDDATVRNTFYNFDNHPQRFSLEPLLGIYEHDAAPVIAGLLEHKDIRRLTED
                     DRYKLAVFVAVQRARTFGELERISGMISVLTDKLAAMGVTEEQAGETLGLSPGGDTRD
                     IFLRQLVQQVSHIKHLLSKDWYLLETRPEHPFYVSDNPVVLENRNDFGVYGNIGLAVP
                     GIQIYLPLSSTLMLAMYCPSIREQKVREKQHLLHLIARAPDLIPRHMRPFEMLEHVNR
                     HTDYLLMPLSAENVMHYNALQVEYAEQYVFCGENDFSLAERMLAADDRYRTGPRFTF"
     gene            13420..16095
                     /locus_tag="RN951_003559"
     CDS             13420..16095
                     /locus_tag="RN951_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528507.1"
                     /translation="MVGSRWYKFDFHNHTPASHDYKIPDISPREWLLAYMKQHVDCVV
                     ISDHNSGAWVDVLKGELENMSRDASTGDLPEFRPLTLFPGVELTATGNVHILAVLHTH
                     STSADVERLLAQCNNNSPIPSEVPNHQLVLQLGPAGIISNIRRNPKAVCILAHIDAAK
                     GVLSLTNQAELTAAFQESPHAVEIRHRVEDITDGTRRRLIDNLPWLRGSDAHHPEQAG
                     MRTCWLKMSSPDFDGLRHALLDPENCVLFDQLPPEEPASYLRSLKFRTRHCHPVGQDS
                     ASVEFSPFYNAVIGSRGSGKSTLIESIRLAMRKTEGLTATQGSKLDQFIRTGMEADSF
                     IECIFHKEGTDFRLSWRPDSKHELHIFSDGEWMPDSHWSADRFPLSIYSQKMLYELAS
                     DTGAFLRVCDESPVVNKRAWKERWDQLEREYLNEQITLRGLRARQGSADSLRGELSDA
                     ERAVSQLQSSAYYPVCRQLALARNELSAATLPLEHFERRIAAIQALAEEPLQRSDIPP
                     EPSGLLMAFMARLSSVQQQYDQRLNTLLAEYAAELAGIRREQSFIALRTAVSDQETNV
                     ESEAVSLRARGLNPDVLNELMARCESLKNELRNYDGLDGAISASVARSEQLLAEMRAH
                     RMALTDNRKAFLSSLSLSALEIKILPLCAPYEDVISGYQTVTGISNFAERIYDNSDGS
                     GLLSDFISERPFSPLPAATEKKYRALDELKALHHSIRLDNSEAGAGLHGSFRNRLRSL
                     NDQQLDALQCWYPDDGIHIRYQTPGGQMEDIAFASPGQKGASMLQFLLSYGTDPLLLD
                     QPEDDLDCLMLSMSVIPAIMSNKKRRQLIIVSHSAPIVVNGDAEYVISMQHDRTGLYP
                     GLCGALQEAPMKALICRQMEGGEKAFRSRYERILS"
     gene            complement(16441..16610)
                     /locus_tag="RN951_003560"
                     /pseudo
     CDS             complement(16441..16610)
                     /locus_tag="RN951_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470624.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
     gene            complement(16606..>17093)
                     /locus_tag="RN951_003561"
     CDS             complement(16606..>17093)
                     /locus_tag="RN951_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001367286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528508.1"
                     /translation="TDEQISKIMRKGNTKEDTWYIFNGVIPPSKIVSVEYMETKDKYI
                     PYDFELHGRGYIENSGIYPISSLLLSDLNHTMRNITFLPGSVIAFCHKANSEENILFR
                     HVLFTCSISLRNFSVLIATGDETSFYIHLDVLKSWTQKNSKVLCQLFEKARESYHRYY
                     G"
BASE COUNT         4275 a         4526 c         4458 g         3834 t
ORIGIN      
        1 agaaaaaaga agaacagtag cagtagcagt agcagtagca gtagcagtag cagtagcagt
       61 agcaggaaca acaacatcat cagtaacaga caaatgacag gtctgaaaag acagaagccc
      121 ccatcagaac gtccgcgtaa tgaaaggggc ggcgcgtgag cgcggcccct ttcagcgcca
      181 ccggcgcgcg gttttttccc ggcgcggaca gacgggcatt tatcctcccg ccagccctgt
      241 gtcatcaggc acgcaaacga ataatcatcg tcgggacatc ggtataagca aacgtgccgc
      301 gcggcagctc ctcgcggacg tcagaaaacg gtaacagctt ctcctgctgg cgtggcccgt
      361 tgagacagac ggcaaccaga acgccccccg gacgcaacag ggaaaaagcc cgcaggatat
      421 gccggatatc ctgcccgtga ctgaacggcg gattcataat gatccggctg taatactgca
      481 ccgactgcca ttccatgaag tcgccacact gtaccctgac accgttaaaa ttttcccgca
      541 gataccggac cagcccgctg ttaatctcca ccgcatcaca catggcctcc ggcgcggtat
      601 cccgaatcgc ccgcagtatg gccccggtgc cggcagaggg ttccagaatg tgatcacggt
      661 tgctgatttc cgccagcgtc accaggcgat cacagatcgg ggcaggactc acaaaaagct
      721 gagattcagc ccggatttca gcaaccggcg cggcgttatc cagccttgcg cgcatcagcc
      781 ggatacgttc tcttaactga ctgtgcatat cattatctcc gtcatccccc ggggatttcc
      841 cggggggata taccttattt ctgtgggatt tccgtgattt tcatgtcggt gatatacaca
      901 ttcaccagac ggaaattatt gtccattgtg cggcggtagc ggtatgcccc gtggtcttct
      961 gcttcttcca cactgcgcac ggccttacag tcccggggca gggcggccca ctgcgccttt
     1021 gtcatttccc ggaaaccttc ccccggatag ttgactaccg gcggacgctt cgcggcctga
     1081 ctggcgacgg cagcctcttc tgccgatggt gctttgtagt ccgtgatgcg atcgggcgtc
     1141 actttcatcg tgccgctgta cccgagaaaa ctgtaatttg gcgttgtgac tgaactcacc
     1201 gccccgttgc ttttgttcac gcggatgata gtcagccact cgccccggct gaaaacctgt
     1261 ccgcccggct caaaatcctg tgtccgggta accacgccgc cgctttcgtc cagcatggca
     1321 cgctcataga tcaggcggtt ctgatagtgg ttaacccagc gttgctgatg ctgaatctgc
     1381 cgttcatgac agcggatcgc aatttcgcgg gcctgctccg tggtgatgat gtcatcatcc
     1441 agggccgacc ataacgaccg gctcccttca tactggcttt tttctgccgg gcgcggatac
     1501 gtatccagcg ggaaacaggc gctgatatgg tcatgactgc tgatgagttt tgccatattc
     1561 agatccagcg attcagcccg ccacatcgtc agatatttct gcgactgtgc gatggtcttt
     1621 tcagccttgc gcaaatcagc ttcgattttt ttgatacgac gccagcgaac gtccgggcgt
     1681 tctttatact tcgcgtgaag cagtgccgac cgcgcccgtt cttcccagta ttccgcacgt
     1741 tcaaagagca tcacggcacg tttcatgccg ttttcaatac gctgcgcatc acgacgggcg
     1801 cggcgttcgc tgtgatgccc cacaagaatg ggctgaccgg gcgggatcat cgcggccagt
     1861 ctttccactt catcaagtgc ctgtgcggat tcactggccc gctttccgct gtatccggta
     1921 aaccgctccg cccgtgcttc ctgacgttca gcgagcgtgc tgtcttcatc ctcaatctct
     1981 ccggcaagtg agaggagcac gtcttcccgg cccggtgtcc aggctggcgc gacaaacagc
     2041 gcctgtctgg gtgcccagcg gaaaccggca tcatgcactt ttttatacgt ctccgggtca
     2101 agacgtgacg cggcatacag gcgcagtttg ttgtcatccg gtgagtaggt cgcgcggtac
     2161 atctgcacag ggctggcggc ttccggggcg gtcatggtga ttgcagctaa tgtcataaaa
     2221 tgttctcctt ccgtctgttg ccgcccctcg cggggcggct cacctcatca gttaaaagcg
     2281 cgtttcagtt cgagtgtgcg gagcacctgc ccgaaagccg tatttttcat ggcggggatg
     2341 tgtacaccac gtccccggtg aaaactccgg gcaatgtgtc gcccgaaggc tttcagcacg
     2401 gggtcaattt ccggcgcggg gatgtcttcg cgtctgaaac ggggatgacg gcggggcttt
     2461 acagccgctg cggaaggtga aacaatactt accgtcataa atgaaactcc ttatgactgt
     2521 tgaatggaac cgcagaaact gctcgaacag tttttgcggt gtggattaag caggtcctcc
     2581 ccggcctgct tttttcatat ctgcgtctga cgttctccgg tgttttcctc cttctgttcc
     2641 tgcgttctca ttacctgcca gccggatgac tgacagaaca aataaatgcg tattgccgga
     2701 gcctgaaata aatcctgatt tttaaagaac atcacccgtt gagtttcggg agccgcggtt
     2761 ttgacgtttc gcgggaacct gctgctgtat tccctgtggt atgaacttca cccgtttgag
     2821 aaccttcgcc gcaaggggca tcactgccac ggcctgacgc acctgtcctg ggcagaacgc
     2881 aaaatttttt accggttttt gggtaaaaaa ttttgtgggc tgttcattta ccctggacag
     2941 tcagtgcggc aggttgtggc tgtctatgcc cccggcgaca gggactcata cgggtgtgtg
     3001 gcacccggca ggcaatgagc aggggcccgc cgcaacgacg gagagcgcgt gcgcgaaacg
     3061 gcgttgcccc ttacatcccg gcggcctttt gccgggatgc cgggagcgca ggccacggcg
     3121 cgacagaggc ggcgcgaccg gaacggtcgc tgcaagccag gggttttcac gcatcggacc
     3181 gtagcggcag cccgaaaccg cgccagcggg ttcggcggag actggcaggt gcgccagcag
     3241 ctgcctgtcg gagtcgggcc tgacgaccgg atgccgccag gcagccggga gccgaaggtg
     3301 cgcgtgcgac aggaagtcgc ttaacgtatt gttttacatt gataaaacca gctatcccat
     3361 tagctgtagc ctaccgggac aggcgctgcc ggcaacggcg gggtctgaag ctcccgggac
     3421 aacgagagcc gggcgtcagc ccgggtaaag ccccgtgagg ggctttacct tgctgcaagc
     3481 atcatgtggc aggagagcaa ggctggtcag aagggttaac acatgtgaac tgttgataaa
     3541 caccgttatc ggcaacaggc caaagatgct gacaggcctg aaccaaaagg tacggggtcc
     3601 ggttgctacc tcgcgcacag ggagcacatg ggcgcagaga cccccggtga agagacagaa
     3661 cccgccctga ccctctgtat gttaagcgga acctggtaaa cccgtatcgc tgccttacag
     3721 gcaggtgaac cgtaaggaac actgtaggcg gtgcgggcag aggaggacgg aaaaagcaaa
     3781 tgcccggttg taatgaccgg gatacggggc aggttccccg acgcgaaagc gggcagactt
     3841 ccgtctggtc tttaattgca tgaaaagctg taaagcagtc aaaaggatat cagcgagatg
     3901 aatacacaca tcagtgtgtc cacgataccc cacccgacag gctggcacac catagactgg
     3961 aaagcatgcc atgcccgggt gcgaaagcta cagttacgga ttgcaaaggc aacccgacag
     4021 caacaatggc ggcaggtcag agaactacag cgcatcctca cccgctcatt ctccggcaaa
     4081 gccgtggctg tcaggcgtgt aactgaaaat accggtaaaa ggacacccgg tattgacgga
     4141 aaaatatggc acacaccgaa ggagaaatgg gaaggaatat gcagcctgaa tctgtgtggt
     4201 tacaggccac agccactacg gcgaatacat atcccaaaat caaacggcaa aacgcgaccg
     4261 ctgggcatac ccacaatgag ggaccgggcc atgcaggcac tgtggctgct ggctctggaa
     4321 cccgtatccg agaccactgc tgaccataac agctatggtt tcagaccaat gcgcagcacg
     4381 catgacgcca ttgagtccat ttttctgcgg atgagccaga aagtatcgcc caaatggata
     4441 ctggagggcg atattaaagg gtgtttcgat aacatcagcc atgactggct gctttcccat
     4501 attccgatgg acaggagact gcttaaaaaa tggttgaaag caggttacat ggaaagaggc
     4561 gtgtttaacc atacgaacag cgggacaccg cagggaggca tcatatcccc tgttctcgcc
     4621 aacatggctc tggacggact ggagaaggaa ctgatgcaaa cgttcaggaa aagtggttat
     4681 cacagtgcaa agcaccaggt gaattatgtg agatatgctg atgatttcat ctgttcaggc
     4741 agctcccgtg aattgctgga aaatgaggtc agaccactga ttgcagcttt catgcgcgaa
     4801 cgagggctgg aactgtcgga agaaaaaacc gcgattacac atatagataa aggcttcgac
     4861 tttttagggc agaacgtcag gaagtacaac ggtaaaatgc tgattaaacc gtcgaagaaa
     4921 aacctgaaga acttcctctg taaagtcaga gaaataatta aacgcaatcc gacgctcccg
     4981 gcatggaaac tgataggcca gctaaacccg gtaatccggg gatgggctac ctatcaccga
     5041 cacgtcgtgg cgaaagaaac atttaattat gtcgacaccc aaatctggcg agctatatgg
     5101 cgatggtgtg taagaaggca cccccgaaaa ggattgcggt ggatcgccgg acgatacttc
     5161 tcctttgaag gcaggcgctg gatctttaaa gccataaccc cggaagggaa aattctgact
     5221 ctcttccggg caatggaaac accgataaag cgccatataa aaatcaaagg cgaagcaaca
     5281 ccatacaccc ccggaatgga aatctacttt gaacgtcgtc tggatctaat ctggaaaggc
     5341 aaatcaaaga agatgaagac agtagttcaa ctctggaaga ggcaggggaa acactgtccg
     5401 cagtgcggac aacccataac caaccagacc ggatggaata tacatcaccg gatcaggaaa
     5461 gttatgggcg gcagtgacga actgaccaat ctcgagttgt tacatccgaa ctgccaccga
     5521 cagttacaca gcagggaagc cggtgctcac cgaaagcact tataaaggct tgagcggagt
     5581 gcggggaaac tcgcacgctc cgttcttagg gggcggcggc gcagcaatgt gccgctgcta
     5641 cccgacccgg cagacagaac aacactgcag tagtcagaat cagagcagca gataaaggaa
     5701 caacaacatc aggaacagtt ccataacata agaaagaaac actcctgagt cagacacatc
     5761 acagacggga agggtaacgg gcgacgcgcc agcgtggccc gcttcccttc cggcaggcgt
     5821 cagcctgcca ggggttttcg cgcggactga caggcggcct ccaccgcctg cccctgtatc
     5881 acctgtttct gctaccctgt aagatgtagt gaccgcccag gaaaaccgcc tgctgattca
     5941 ccacaaaatc gcagatttca tcaacaatct gcgcggtggt gagcggtttc tgccccattt
     6001 cacgacgccg cgcattaatc acggccctgt aattacgcag aattccgcgg gtttctgtgc
     6061 tgatattcat gacatcgtct ccccgtccag cgcctgtaac acaacgtcca ttgcttcgcg
     6121 ttcctccctg acgaatgcgt caccgtcgcc cccgttctca ctcccgacgg catacaggcg
     6181 cttcatttca ctgcctgcca gcgccatcac tttttccagc atcaccgccg ggactgtcac
     6241 ctgacggctg gcgcgctttt cttccatcag ttcacgaaca acgccgtgaa caacgctgac
     6301 atccgcacca tgctcaaagg catcgtccag tcgctgcatg acggtttcca gctcatcgtc
     6361 tgacaggttc cagtcctggg ctatgtgacg cacatcccct cgggtcagca ccacggcaaa
     6421 aacgcattca ctgtccggca cgtctgtatc cagtacatcg cggatgattt ctttaacagt
     6481 acagtacatg ttctcgtctc ctttacaggg gcggcattgc cgccccgtcc gttaatcagt
     6541 ccagtgctgc gtaaatcgcg ttgcattcag ggtgaaattc gatgtgacgc cacaactgcg
     6601 catcgcgcat ccggtaaagc tgggtcagtc ctgcatcccc gctgtcgtgg tacagccaca
     6661 actggcggtt aatcacaagg gaggtaagga tgatgcctgc ggcatcagca ctcacggtac
     6721 ggtcaaacca gtttgcaccg ttcaccatgt ggaaacggtc gccatccggc atcatgtaac
     6781 cgccaccgtc cggcaggcgg atgaagtgcc agaagcctcc ctgatactcc ggcatcattt
     6841 ttttcgccag cgcgtacaca tacgcctcgg catacagaaa atcgttgcca aacaggtaag
     6901 gcagaaagga gagacggtcg cactcttcaa cattcagagt gacaggtttc gcatattgca
     6961 tgatgttttc ctccgttatt cacatattcc gcgacaccgg gcggtgccgt gcctccataa
     7021 aagccgggcg ataaggcggg gatgcacagg gcgcaaggga agccgcagcc tgacgcacac
     7081 ggctggcggg agttggaggg tgagaccgcg aaatctgagc gggtgaacga ccggaaaatc
     7141 acggcagacg ggaaggaggg accgggtgac cgcagcggcg aagcgtaccc ttgcatccct
     7201 gccagcccga ctaagatgga ggcacggcac agcccgcaca cgacacagcg gccacataac
     7261 tgaaaaccca caaggccatg ccccgcatgg ccgggtaaag cggagccggc ggcgacttcc
     7321 ttagtccctg atttttgcca gggcatccgc catgctgcgg atttctaccc gggcttcccg
     7381 gaccacctcc cgcagaacac cacggtcaaa ccagcggcgg ggcggttcat ccggtatacg
     7441 cagcacatcg caggccagcc cactggacag gatatgctca atacaatcgc tgaccaggta
     7501 catttccacc gacgaaaaac gtgctccccg gttcacgatg gcatcgagca ccacgggcag
     7561 gttttcgtca tcttcatcga gccagcaggg gtgatcgctt tccttcacaa ccagacgaaa
     7621 gcggcgcgtc tggcgggtca gcaacgtctg accggtggtg gtcagcgccg cccggatacg
     7681 ccgcgcatcg tctgccacct ggtaacagat gcttcgtatt gcatcgcgca ccgccgcaag
     7741 tacagccctg atttcgtctt ctgccagcca ctcaccggca tacgggaaag acacctgcgt
     7801 tccgtctgcc ggaagtaccg gcagcgactg ccactgactg ccggacagaa caagttccgc
     7861 cccggttccg gtcagtttct gaatggcaga ggccaggtgc ggcggcagta cgccgccgtg
     7921 acggttgata agtaacgtcg ccagccgggg cgcatccagc cgcacgtaaa tgctgatcca
     7981 gcccggatgg ttcggatttc gctggtcaac atccgtctct tccggccagc cctgcgccag
     8041 cagcaggtta cgggcgtggc gacaaatcag tgcattcagc gtttcgttca tgattcatgg
     8101 tctccctgaa tcgccgcccg caggcggcga taacatcagt cgttttcgcg tgtgttgttt
     8161 ttcagcaggg cgcgggcctg attaaccacc gcctgtcggc gggtgacgca ttccgggacg
     8221 acgaggccgt tatcacgggc ggcccactca cgtttccaca gtgcctgttc agcggtctga
     8281 atcagggacg ccagcagttc agcagggacg gtcacctggc ggttttcgct cacgttgctg
     8341 ataatctcca tcaccgcggc ggaagaaata ccggattcag tcctctggtc ttccgggatg
     8401 tcctccatgc gcgccaggac ggccctgatt tcatgatcgg tcagagaaat ttccataccg
     8461 tcagccagtg cctgaatctc ttccggagac cagataacca gcatcagcgg cgtgtctccc
     8521 ggatactttg cttccagctc ccggcagagc gtttcgcatg ttccgtacat ttcgtctccc
     8581 ccttaatctt tgaagcacgc atccagttca agaatttcgg tatatgcctc catgaacagg
     8641 cgattggcgc gatacagcgt ctggcgtgcc aggcgttcga cgagcacatc ggaatcaaag
     8701 cgacagcgat gctccatatc gttcagcctg gcccgaaggt cacacatggc attggccacc
     8761 tccgccactt cagcacgaag gttttcgtgt ccggcatagt tcatttacgc agcctccggt
     8821 tcaaaccagt tatcattcgc ggccccctgc tgcatggccc gttgcacggt ggccagtcgt
     8881 tgctgtccgg cacggtgata ctgttcaagc agctcgatac cgatataccg gcgtccggac
     8941 tgaagggcag ccacacaggt tgagccgctg ccagcaaacg ggtctagcac aattgcgttc
     9001 gggtgtgtga agctctcaat cagcggttgc aggctggtaa caggcttttc cgtcgggtga
     9061 tggcggttgc ccgaatattt ccagcccagc acgtcgggta atggcttcgg aggcagcgcc
     9121 ggacggcctt ttgccaggat ataggcgcat tcgtgacggt acgcgacata cgcagatttg
     9181 gatgtgtagc ttttggtgaa cacaaggtgc cctacaacgc tgaatccggc gcgtttccag
     9241 gctgccataa agcggtcaat acggttccag ccatagaaac tcaccatcag cgcatctttt
     9301 tttagtacgc ggtacatctc attactggca ggttgcagcc agtcatcgtt aacgtcaccg
     9361 gcaatggtgc gcccggaacg gtcacgaaaa ccaacgagat atggtgggtc ggttaagatg
     9421 aaatcaatgg cgttatcagg aatcgtggcc ataacacgca cgcagtcacc caggataaaa
     9481 cgggacataa cagcactcct cctcttacag agggcaccgg gagggcgccc ctgtggcgcc
     9541 cgttctccgc tgcctgtggg ctgttcaccg cgtccggtaa cgggtcaggc cgaccgtgga
     9601 ataccgcagc cgtcgtcttt ctgacggcga ggatatgccg cgaaagcggc ttgaagggca
     9661 ttcatcagaa aagggcgaca ggctggcgta cactgtcacc gacgccagcc aggagcggta
     9721 aaagcgcccg tcccgtgccc ggccggacgc gggacactga ccacaggcag cgttcctgcc
     9781 gcgccgcgtc agccggcgca gtaaaaagag aagcacagcg acatcttttg ttacccgcca
     9841 aataaaaccc aaaaacaacc caaaacacac cataataaac ccaaaaacaa tacaaacaat
     9901 cattgactga tagtcaaaat ggggtaaact tgacaaacga ccccatttaa aacccaaaac
     9961 aaccccaaaa gcacaccaca aaaacaccat aaggagtttt ataaatgttg gtattcattg
    10021 atgacggttc aacaaacatc aaactacagt ggcaggaaaa cgacggaaca attaaacagc
    10081 acattagccc gaacagcttc aaacgcgagt gggcagtctc ttttggtgat aaaaaggtct
    10141 ttaactacac actgaacggc gaacagtatt catttgatcc aatcagcccg gatgctgtag
    10201 tcacaaccaa tatcgcatgg caatacagcg acgttaatgt cgttgcagtg catcacgcct
    10261 tactgaccag tggtctgccg gtaagcgaag tggatattgt ttgcacactt cctctgacag
    10321 agtattacga cagaaataac caacccaata cggaaaatat tgagcgtaag aaagcaaact
    10381 tccggaaaaa aattacatta aatggcgggg atacattcac aataaaagat gtaaaagtca
    10441 tgcctgaatc tataccggca ggttatgaag ttctacaaga actggatgag ttagattctt
    10501 tattaattat agatctcggg ggcaccacat tagatatttc tcaggtaatg gggaaattat
    10561 cggggatcag taaaatatac ggagactcat ctcttggtgt ctctctggtt acatctgcag
    10621 taaaagatgc cctttctctt gcgagaacaa aaggaagtag ctatcttgct gacgatataa
    10681 tcattcacag aaaagataat aactatctga agcaacgaat taatgatgag aacaaaatat
    10741 caatagtcac cgaagcaatg aatgaagcac ttcgtaaact tgagcaacgt gtattaaata
    10801 cgctcaatga attttctggt tatactcatg ttatggttat aggcggtggc gcagaattaa
    10861 tatgcgatgc agtaaaaaaa cacacacaga ttcgtgatga acgttttttt aaaaccaata
    10921 actctcaata tgatttagtt aacggtatgt atctcatagg taattaatga tggacaagcg
    10981 cagaaccatt gcctttaagc taaatccaga tgtaaatcaa acagataaaa ttgtttgtga
    11041 gacactggac agtatcccgc aaggggaacg cagccgcctt aaccgggctg cactgacggc
    11101 aggtctggcc ttatacagac aagatcccag ggcccctttc cttttatgtg aactgctgac
    11161 gaaagaaacc acattttcag atatcgtaaa tatattgaga tcgctatttc caaaagagat
    11221 ggccgatttt aattcttcaa tagtcactca atcctcttca caacaagagc aaaaaagtga
    11281 tgaagagacc aaaaaaaatg cgatgaagct aataaattaa ttcaattatt attgagttcc
    11341 ctttatccac tatcaggctg gataaaggga acttaatcaa gttattttat tggcaattat
    11401 tacataaaat aaatacagcg tcgttattat gaaattattt cacggcactt ataccaataa
    11461 tcaaacttgg tgagttcgca atgtctggca ataacgtttt tgatgggttg tttgccagcc
    11521 cagagcgcga tattgccgcc agtcacggaa acaccgtatt catataccat gttgatgatg
    11581 ataaaatagc taaatccagc gatcttgatg ctcgttttca agaggtttat gccttcttac
    11641 ataacgaact ggatactgct gacgtagagg aaatagctga tcgcgtcatg tgggataaca
    11701 attcagatat cgaagatttc gcagatattc tctcgccacg cctcggcagc gatattaatg
    11761 gagcatactc atgggaattg caacgcctgc gtggtcgtgt agccgcttat cttggatttg
    11821 atgccataga aatgaacgat gaatacggca caagttacct cattgtgaat ccacaaatta
    11881 aagatgaata aaatgaattc ccgcattaga gggaccagat attctccagt acctcctgtc
    11941 ctgcaaggct atacggtctg tcagcaatga aaattgctgt acgcggttga agaatttacc
    12001 cgcagccggg ccgtgagggc cgcttacgaa cgtgtatgac agagttacat ttatacaatg
    12061 tcctgcaggg aacggacatc ggcattttgc ggcactgcgc tgaccggaag ttgccctaaa
    12121 atgtaaaccg cggcccggtc cggtaacggt catctgcagc cagcattctt tcagccagag
    12181 aaaaatcgtt ttcaccgcag aacacgtact gttcagcata ctccacctgc agcgcgttat
    12241 aatgcatcac attttctgca gaaagtggca taagaagata gtccgtatgc ctgttgacat
    12301 gctcgagcat ttcaaacggg cgcatgtgac gcgggattag atccggcgct ctggcaataa
    12361 gatgaaggag atgctgcttt tcacgaactt tctgttcacg gatggaaggg caatacatgg
    12421 ccagcatcag cgtcgatgac aggggcagat agatttgtat gccgggcacg gctaggccga
    12481 tattaccgta cacaccgaag tcattgcggt tctccagtac caccggattg tctgacacat
    12541 agaacggatg ttctggcctg gtttccagga ggtaccagtc cttacttagc aggtgtttaa
    12601 tatgcgacac ctgctggaca agctgccgca gaaaaatgtc tctggtatcg cccccgggcg
    12661 ataaacccag agtttctcct gcctgctcct cagtcacgcc cattgccgcc agcttatcag
    12721 tcagcaccga aatcatgcct gagatacgtt ccagctcacc gaaggtacgt gcgcgctgca
    12781 cggcaacaaa cacggccagc ttgtagcggt catcttcagt cagccggcga atgtccttat
    12841 gctccagtag gccggcaatg accggtgccg cgtcatgttc gtaaatcccc aacaacggtt
    12901 caagactgaa tcgttgaggg tgattatcga agttgtagaa cgtattccgg acggtggcgt
    12961 catccggcgt ggtggcataa gcacgcccgg cagccttatc aaaggcgtgt aaacgctggc
    13021 gttttccctt taccggcttg ctgaagtgct tcagtaaaaa acgggggact gtgtgctgcc
    13081 tgacaacgtc ggtccgcagg tttaatggtt cggtcatgga aattatcatc cttgatggac
    13141 tggtactgta gattcaccgt ggaccagcga atctattatg tggtgagcag aacattaaca
    13201 catcaatgta acgccgtaat cattgagtct ttgccgggga cgcttgacat ctccgaaaga
    13261 attatatcgt gagtcttaag gggaatctct tgcttccggt tatacattta accggatcta
    13321 gctataagac tgttacatct attgggatta ggtcaggaca gatagcctga aagcttttat
    13381 agtgagggac ttcagaaata ccctagaaaa ggaactgtta tggtaggttc gcgctggtat
    13441 aaatttgatt ttcataacca tactccggct tcgcatgatt acaaaattcc tgacatcagc
    13501 cccagagagt ggcttctggc ttatatgaaa cagcatgtcg attgtgttgt aatcagcgat
    13561 cataacagcg gagcctgggt cgacgtgttg aagggtgagc tggagaatat gtcccgggac
    13621 gccagcaccg gcgacctgcc ggaatttcgg ccactgacac tctttccggg ggttgaactg
    13681 acagcgaccg gtaacgtaca tattctggct gtgctgcaca cgcacagtac aagtgccgat
    13741 gtggaaaggc ttctggccca gtgcaataat aatagcccca ttccgagtga agtccctaac
    13801 catcagctcg ttcttcaact gggccccgcc ggcatcatca gtaatatccg ccgtaatccg
    13861 aaggctgttt gtattcttgc gcacattgat gcagccaaag gtgtcttaag tctgactaat
    13921 caggcagagc tcaccgcagc ctttcaggaa agtccccatg ccgttgagat tcgacaccgg
    13981 gtggaggata tcaccgacgg aacccgccgg cggctgattg ataatttacc gtggctacgg
    14041 ggctctgatg cgcaccatcc tgaacaagcc ggcatgcgaa cctgctggct gaaaatgtca
    14101 tcccctgatt ttgacggact caggcatgca ctgctcgatc cggaaaactg tgtgctgttt
    14161 gatcagctcc ctccggagga acctgcgtca tatttgcgca gcctgaaatt cagaacccgc
    14221 cactgccatc ctgtgggtca ggattcggcc tcggtggaat tcagcccgtt ctataacgct
    14281 gtaatcggct caagaggcag cgggaagtcc acgctcattg aaagcattcg tcttgcaatg
    14341 cgcaaaacag aaggtctcac tgcgacccag gggagtaagc tggaccagtt cattcggacg
    14401 gggatggaag cggattcctt catcgaatgt attttccaca aagaaggcac agatttccgg
    14461 ctcagttggc gaccagacag taagcatgaa ttacatatct tcagtgacgg agaatggatg
    14521 cctgacagtc actggtcggc tgaccgtttt ccactctcga tttacagcca gaaaatgctc
    14581 tatgagctgg cttcggatac tggtgcattc ctgcgcgtct gtgatgagag cccggtggtt
    14641 aacaaacggg cctggaaaga gcgctgggat cagctggaaa gggaatatct gaatgaacaa
    14701 atcacgttgc ggggcctgcg tgccagacag ggaagtgcgg attcgctgcg gggggaatta
    14761 tcggatgctg aacgtgccgt cagtcagctg cagtcaagcg cctattatcc ggtttgcaga
    14821 cagctggccc tcgccagaaa cgagctgtcc gcagcaacct tacccctgga gcactttgag
    14881 cggcgtattg cagccattca ggctctggca gaagaaccgc tgcagagatc cgatatcccg
    14941 ccggaacctt ccggtctgct gatggcattt atggcgcgcc tgtcatctgt gcaacagcag
    15001 tatgaccagc ggctcaatac tctcctggca gaatatgctg cagagctcgc gggtatcagg
    15061 agagagcaat cttttattgc cctccgaaca gcagtgagtg accaggaaac aaatgtagaa
    15121 agtgaagctg tttccctgcg ggccagaggg cttaatcccg atgttctcaa cgaactgatg
    15181 gcacgctgtg agtcactgaa aaatgagctg agaaattacg acggtcttga tggggcgatc
    15241 tctgcctctg ttgcacggtc tgagcagttg ctggctgaaa tgcgtgccca cagaatggca
    15301 ttgacagata accggaaggc gtttctctcc tccctgtcgc tcagcgctct ggaaatcaaa
    15361 attcttcccc tctgcgcccc ttatgaagat gttatatctg gttaccagac ggttaccggc
    15421 atcagtaatt ttgccgaacg tatctacgat aacagtgacg ggagcggatt actgagcgac
    15481 tttatcagtg aacgtccgtt cagcccgttg cctgccgcaa cagagaaaaa atacagggcg
    15541 ctggacgagc tgaaagcgct gcatcacagc atccggctgg ataattcaga ggctggggcg
    15601 gggcttcatg gttctttccg gaatcgtctc aggagtctga atgaccagca gctggatgcc
    15661 ctgcaatgct ggtatcctga tgacggcatc cacatacgtt accagacccc cggggggcag
    15721 atggaagaca ttgcctttgc ttctccgggg caaaagggag cgagtatgct gcagttcctc
    15781 ttatcctatg gcaccgatcc tctactactg gatcaaccgg aggatgacct ggactgcctg
    15841 atgctgagca tgagcgtgat ccctgccatc atgtcgaaca agaaacgccg gcagctgatt
    15901 atcgtgtcgc actctgcccc tatagtggtt aacggcgatg cagaatatgt tatcagtatg
    15961 cagcacgatc gcacaggcct gtatccagga ctctgcggtg cactgcagga agctccgatg
    16021 aaggcactga tatgccgtca aatggagggg ggagaaaaag cgtttcgttc gcgctatgag
    16081 cgtattctta gctgaagaac ggaaccgtcc ttaaggcggc cacgaccgga gagtgggcct
    16141 ggcggctgaa tgcctggata aaagacgcaa atgtcagact gatggcctct gcgtctttgt
    16201 cagcgccagt gatataagac ggtaatgggg atgcggacga tttcctggac tctcaggaga
    16261 tgaaacatgt ttactgaaaa acaaaaaatc cgcgccattg agcttttttg tcgggataaa
    16321 acggaaagcc gctggccagc cagctgttgt ttactcgtca cgcgacaggc aagcctgttc
    16381 aaaaaacagg cttgccgtac aataattctc tatatccaaa ctgacccctt atagagagcc
    16441 tgacagaggc tgccatgata tgggcacatc aagaatgaca atccacactc gtgttgttct
    16501 atctgctcaa ccagcaagat atcattgcga tgactgtcca tcagtaagcg tcccggttcc
    16561 gggcggtcta gttttgtgcc actgatgttc tccccgcagt ggtttctaac catagtatct
    16621 gtggtaactt tcacgtgctt tttcaaaaag ttggcatagt actttactgt ttttttgagt
    16681 ccaacttttt aatacatcca gatgaatata gaaagatgtc tcatcacctg ttgctatcag
    16741 tactgaaaaa tttctcaagg agattgaaca tgtgaataat acatgtctga ataaaatatt
    16801 ttcttctgaa tttgctttat gacaaaacgc tatgacagaa cctggtaaaa atgtaatatt
    16861 tcgcattgta tgattcagat cagataataa taaactcgaa atcggataaa tgccggagtt
    16921 ttctatatat ccccttccat gcaattcaaa atcatatggt atatatttat ctttagtttc
    16981 catatattca acagagacta tttttgaagg tgggatgacc ccattaaaga tataccaggt
    17041 atcttctttt gtgttacctt ttcgcataat tttacttatc tgctcatcgg tca
//
LOCUS       DAPOAV010000092        16953 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.092, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000092 DAPOAV010000000
VERSION     DAPOAV010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16953
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.092"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            129..590
                     /locus_tag="RN951_003562"
     CDS             129..590
                     /locus_tag="RN951_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegJ family protein"
                     /protein_id="HDX2528509.1"
                     /translation="MKKILLMLSLLFFTTAGFSEVSDTLVTGGYDKQAMSDAIKHARK
                     ETDKFIEVMNKKDADTFAVKAPITDHGRTEHFWLTDVTYSNGMFIGVISNDPGIVTNV
                     EYGQEWKIKKEDISDWMYTRGDKIYGGYTIDPLLVTYPKEEADELRAKLVR"
     gene            complement(655..1416)
                     /gene="pphC"
                     /locus_tag="RN951_003563"
     CDS             complement(655..1416)
                     /gene="pphC"
                     /locus_tag="RN951_003563"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase PphC"
                     /protein_id="HDX2528510.1"
                     /translation="MSWRLVYASAVGTSHISADLPCQDACQMQVAWLNDQQPLLVMFL
                     ADGAGSVSQGGEGAMLAVNEAMAYMSQKVQGGELGLNDILATDIVLTIRQRLFAEAEA
                     KELAVRDFACTFLGLISSANGTLIMQIGDGGVVVDFGHGLQLPLTPMVGEYANMTHFI
                     TDEDAVSRLETFTSTERVHKVAAFTDGIQRLALNMLDNSPHVPFFTPFFNGLASATQE
                     QLDLLPELLKQFLSSPAVNERTDDDKTLALALWAE"
     gene            complement(1413..2072)
                     /locus_tag="RN951_003564"
     CDS             complement(1413..2072)
                     /locus_tag="RN951_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDX2528511.1"
                     /translation="MSEQITFATSDFASNPEPRCPCILLLDVSGSMNGRPINELNAEL
                     VTFRDELLADSLALKRVELGIVTFGPVHVEQPFTSAANFFPPILFAHGDTPMGAAITK
                     ALDMVEERKREYRANGISYYRPWIFLITDGAPTDEWQAAANKVFQGEEDKKFAFFSIG
                     VQGADMKTLAQISVRQPLPLQGLQFRELFSWLSSSLRSVSRSTPGTEVVLEAPKGWTS
                     V"
     gene            complement(2294..2353)
                     /gene="ibsA"
                     /locus_tag="RN951_003565"
     CDS             complement(2294..2353)
                     /gene="ibsA"
                     /locus_tag="RN951_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsA"
                     /protein_id="HDX2528512.1"
                     /translation="MMKHVIILVILLVISFQAY"
     gene            complement(2626..2682)
                     /locus_tag="RN951_003566"
     CDS             complement(2626..2682)
                     /locus_tag="RN951_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HDX2528513.1"
                     /translation="MMKWIIIVVLLVISFPAY"
     gene            complement(2954..3010)
                     /locus_tag="RN951_003567"
     CDS             complement(2954..3010)
                     /locus_tag="RN951_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HDX2528514.1"
                     /translation="MMKILIIVVLLVVSYPAY"
     gene            3289..4536
                     /gene="mdtA"
                     /locus_tag="RN951_003568"
     CDS             3289..4536
                     /gene="mdtA"
                     /locus_tag="RN951_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter subunit MdtA"
                     /protein_id="HDX2528515.1"
                     /translation="MKGSYKSRWVIVIVVVIAAIAAFWFWQGRNDSQSAAPGATKQAQ
                     QSPAGGRRGMRSGPLAPVQAATAVEQAVPRYLTGLGTIIAANTVTVRSRVDGQLMALH
                     FQEGQQVKAGDLLAEIDPSQFKVALAQTQGQLAKDKATLANARRDLARYQQLAKTNLV
                     SRQELDAQQALVSETEGTIKADEASVASAQLQLDWSRITAPVDGRVGLKQVDVGNQIS
                     SGDTTGIVVITQTHPIDLVFTLPESDIATIVQAQKAGKPLVVEAWDRTNSKKLSEGTL
                     LSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVDTEQNAVVIPTAALQMGNE
                     GHFVWVLNSENKVSKHLVTPGIQDSQKVVIRAGISAGDRVVTDGIDRLTEGAKVEVVE
                     AQSATTPEEKATSREYAKKGARS"
     gene            4536..7658
                     /gene="mdtB"
                     /locus_tag="RN951_003569"
     CDS             4536..7658
                     /gene="mdtB"
                     /locus_tag="RN951_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtB"
                     /protein_id="HDX2528516.1"
                     /translation="MQVLPPSSTGGPSRLFIMRPVATTLLMVAILLAGIIGYRALPVS
                     ALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVITL
                     QFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPM
                     TQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAIT
                     GANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAE
                     NSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDRTT
                     NIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFS
                     INNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFS
                     LIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCARMLSQESLRKQN
                     RFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQD
                     NGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQ
                     INLKPLDERDDRVQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQAT
                     SLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNA
                     LYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKI
                     EQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGST
                     LAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALLIAGS
                     ELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPREAIYQACLLRFRPILMTT
                     LAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTK
                     SRFARHEEEA"
     gene            7659..10736
                     /gene="mdtC"
                     /locus_tag="RN951_003570"
     CDS             7659..10736
                     /gene="mdtC"
                     /locus_tag="RN951_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtC"
                     /protein_id="HDX2528517.1"
                     /translation="MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPV
                     IMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDIN
                     GAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFAST
                     QLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAVSNANVRKPQG
                     ALEDGTHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTN
                     AKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRASLEEV
                     EQTLIISVALVILVVFLFLRSGRATIIPAVSVPVSLIGTFAAMYLCGFSLNNLSLMAL
                     TIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLL
                     LMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFGRML
                     VALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQA
                     DQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRDERSETAQ
                     QIIDRLRVKLAKEPGANLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRK
                     KLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIY
                     QPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGL
                     SAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILI
                     IAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLI
                     GIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLLLSG
                     GDGSELRHPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQTVTE"
     gene            10737..12152
                     /locus_tag="RN951_003571"
     CDS             10737..12152
                     /locus_tag="RN951_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2528518.1"
                     /translation="MTDLPDSTRWQLWIVAFGFFMQSLDTTIVNTALPSMAQSLGESP
                     LHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFFTAIVLFTLGSLFCALSGTLNELL
                     LARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTFVTLPGQVGPLLGPALGGLLVEY
                     ASWHWIFLINIPVGIIGAIATLLLMPNYTMQTRRFDLSGFLLLAVGMAVLTLALDGSK
                     GTGLSPLTIAGLVAVGVVALVLYLLHARNNNRALFSLKLFRTRTFSLGLAGSFAGRIG
                     SGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQVVNRFGYRRVLVATT
                     LGLSLVTLLFMTTALLGWYYVLPFVLFLQGMVNSTRFSSMNTLTLKDLPDNLASSGNS
                     LLSMIMQLSMSIGVTIAGLLLGLFGSQHVSVDSGTTQTVFMYTWLSMALIIALPAFIF
                     ARVPNDTHQNVAISRRKRSAQ"
     gene            12149..13552
                     /gene="baeS"
                     /locus_tag="RN951_003572"
     CDS             12149..13552
                     /gene="baeS"
                     /locus_tag="RN951_003572"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     BaeS"
                     /protein_id="HDX2528519.1"
                     /translation="MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIK
                     HGNEQRLQLLSDALGEQYAQHGNWRFLRNNDRFVFQILRSFEHDNSEDKPGPGMPPHG
                     WRTQFWVVDQNNKVLVGPRAPIPPDGTRRPILVNGAEVGAVIASPVERLTRNTDINFD
                     KQQRQTSWLIVALATLLAALATFLLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSED
                     ELGKLAQDFNQLASTLEKNQQMRRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPE
                     TVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLEVAGGAFRERFASRG
                     LKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLQISAGQRDKTVRLTFAD
                     SAPGVSDDQLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGG
                     VSITVELPLERDLQREV"
     gene            13549..14271
                     /gene="baeR"
                     /locus_tag="RN951_003573"
     CDS             13549..14271
                     /gene="baeR"
                     /locus_tag="RN951_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BaeR"
                     /protein_id="HDX2528520.1"
                     /translation="MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGD
                     QVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFSDIPIVMVTAKIEEIDRLLGLEI
                     GADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLD
                     LTPAEFRLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAE
                     QSFIRAVYGVGYRWEADACRIV"
     gene            14462..14794
                     /locus_tag="RN951_003574"
     CDS             14462..14794
                     /locus_tag="RN951_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310915.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HDX2528521.1"
                     /translation="MAGWFELSKSSDNQYRFVLKAGNGETILTSELYTSKASAEKGIA
                     SVRSNSPQEERYEKKTASNGKFYFNLKAANHQIIGSSQMYATAQSRETGIASVKANGT
                     SQTVKDNT"
     gene            14941..16302
                     /gene="yegQ"
                     /locus_tag="RN951_003575"
     CDS             14941..16302
                     /gene="yegQ"
                     /locus_tag="RN951_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-hydroxyuridine modification protein YegQ"
                     /protein_id="HDX2528522.1"
                     /translation="MFKPELLSPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFN
                     HENLQLGINEAHALGKKFYVVVNIAPHNAKLKTFIRDLKPVVEMGPDALIMSDPGLIM
                     LVREHFPEMPIHLSVQANAVNWATVKFWQQMGLTRVILSRELSLEEIEEIRNQVPDME
                     IEIFVHGALCMAYSGRCLLSGYINKRDPNQGTCTNACRWEYNVQEGKEDDVGNIVHKY
                     EPIPVQNVEPTLGIGAPTDKVFMIEEAQRPGEYMTAFEDEHGTYIMNSKDLRAIAHVE
                     RLTKMGVHSLKIEGRTKSFYYCARTAQVYRKAIDDAAAGKPFDTSLLETLEGLAHRGY
                     TEGFLRRHTHDDYQNYEYGYSVSDRQQFVGEFTGERKGDLAAVAVKNKFSVGDSLELM
                     TPQGNINFTLEHMENAKGEAMPVAPGDGYTVWLPVPQDLELNYALLMRNFSGETTRNP
                     HGK"
     gene            complement(16633..16950)
                     /locus_tag="RN951_003576"
     CDS             complement(16633..16950)
                     /locus_tag="RN951_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416589.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528523.1"
                     /translation="MNKIAAISLISVFLMSGCAVHNDETSIGKFGLAYKSNIQRKLDN
                     QYYTEAEASLARGRISGAENIVKNDATHFCVTQDKKMQIVELKTEGVGLHGVARLTFK
                     CGE"
BASE COUNT         3931 a         4518 c         4496 g         4008 t
ORIGIN      
        1 gggaagagcc cactcaagaa taaaaatgat aatgtaattt catcaggata caattcaatt
       61 ccaacctgat aatgattcac ttccacaggt tttgctaact tttactacac agagattctg
      121 gagaaaaaat gaaaaagata ttactcatgt tgagcctgct attttttact accgcgggct
      181 ttagtgaagt ttcggatacg ttagtgacag gaggttatga taaacaagcg atgtctgacg
      241 cgattaaaca tgcgcggaaa gaaaccgata aattcatcga ggttatgaat aaaaaagatg
      301 ccgatacttt cgcagtcaaa gccccgataa ccgatcacgg aagaaccgag catttctggc
      361 tcacggatgt cacttattct aacggcatgt ttattggcgt aatcagcaat gaccctggta
      421 ttgttacaaa cgtagaatat ggccaggagt ggaaaatcaa gaaagaagat atttcagact
      481 ggatgtatac gcgcggggat aaaatttacg gcggttatac cattgatcct ttattggtca
      541 cctatccaaa agaagaagcc gacgagctta gagcaaaatt agttcgctaa tcagccgtta
      601 tatttattgt ttaaactggc ggttgaattg ttgtcttcaa ccgccatgag aaactcactc
      661 tgcccacagc gccagtgcta acgttttatc atcatcggta cgctcgttta ccgctgggct
      721 ggacaaaaac tgctttaaca attcaggtaa taaatcgagt tgttcctgcg ttgctgacgc
      781 cagtccattg aaaaacgggg taaagaaagg cacatgcgga gaattatcca acatatttaa
      841 cgccagtcgc tggataccat ccgtaaatgc tgcaacttta tgcacacgct cagtgctggt
      901 gaaagtttcc agtctggaaa cggcatcttc atcggtaatg aagtgcgtca tattggcata
      961 ttcacccacc atcggcgtaa gcggcaattg cagaccgtga ccaaaatcca ccaccacgcc
     1021 gccatcgcca atctgcataa tcaaggtgcc attagccgat gaaatcaatc ccagaaacgt
     1081 gcaggcaaaa tcgcgaactg ctaattcttt ggcctctgcc tcggcaaaaa gtcgctgacg
     1141 aatagtcagc acaatatccg tggcgaggat atcattaagc cccaattccc caccctgcac
     1201 tttttgcgac atataagcca tcgcttcatt gacggcgagc atcgcgcctt cgccaccctg
     1261 cgagacgctg cctgcaccat cagcaagaaa catcaccagt aatggttgct gatcgtttaa
     1321 ccaggcaacc tgcatctggc aggcatcctg acaaggtaaa tcagcgctaa tgtgcgacgt
     1381 tccaacggct gatgcataaa ccagacgcca gctcacactg acgtccagcc ttttggcgct
     1441 tccagcacaa cttccgttcc cggcgtggag cgggaaaccg aacgcagcga actggataac
     1501 cagctaaata gttcgcggaa ttgtaatcct tgaagaggca aaggctgacg aacgctgatt
     1561 tgggccagcg tcttcatatc cgccccctga acaccgatgg aaaagaaggc aaacttctta
     1621 tcttcttccc cctgaaacac cttgttggca gcagcctgcc actcatcggt tggtgcacca
     1681 tcggtaatca ggaaaatcca cgggcgataa tacgaaatac catttgcacg atactcacgt
     1741 ttccgctcct ctaccatatc cagggctttg gtaatggcgg cgcccattgg tgtatcccca
     1801 tgggcaaaca ggatgggcgg gaaaaaatta gcggcactgg taaatggttg ttccacatgc
     1861 accgggccga acgtcacaat accgagttcc actcttttta aggccagcga atcggcaagc
     1921 agctcatcgc gaaaggtaac caattcggcg ttaagttcat taataggtct accgttcata
     1981 gaaccagaaa catccagcag caaaatgcag gggcaacgtg gttccgggtt actggcaaaa
     2041 tcgctggtgg caaacgtgat ttgttcgctc ataagaaatc ctttcttaga gaattattga
     2101 ggtccggtat cataccgatt gcaataatga aataagagca aacgaagaaa ctttcagaat
     2161 taggcccggc ggcgcagaaa attttgctat tcgcctcgca agaacggaga gccgtcgatt
     2221 gacactaagg gcggagtgac ataatttcag gagtgagggt tagggagagg tttcccccct
     2281 ccccctggtg ttcttagtaa gcctggaagc taatcactaa gagtatcacc agtatgatga
     2341 cgtgcttcat cataaccctt tccttattaa aagccctctt ctccgggaga gggtttcccg
     2401 tttcagcgtc ccgctgaaat cgtcggctta cctcctttcg ccctgaatgc agtctatcgc
     2461 taacgcgtga acaaaatagt ttcctctgtg attattgcgt aacgactcgc aaagaatatt
     2521 tgctggcagg atcgcagact acaaagcctg cggattgaca atcttatcgt gaaggcataa
     2581 tttcaggagt gagggtagag cggggtttcc cccgccctgg tagtcttagt aagccgggaa
     2641 gcttatgact aagagcacca cgatgatgat ccacttcatc atgacccttt ccttatttaa
     2701 ggccccttcc tcgggagggg ctttcccgtt tcagcgtccc gctgaaatca tcggcttacc
     2761 tcctttcgcc ctgaatgcag tctatcgctg acttgcggat aaaatagttt cacatgtgat
     2821 tattgcgtga cgtctcgcaa agaatatttg ctggcaggat cgcagactgc aaagcctgcg
     2881 gattgacaat cggaccgtga aggcatactt tcaggagtga gggtagagcg gggtttcccc
     2941 cgccctggta gtcttagtaa gctgggtagc taacgactaa gagcaccacg atgatgagta
     3001 tcttcatcat gaccctttcc ttatttaagg ccccttcctc gggaggggct ttcccgtttc
     3061 agcgtcccgc tgaaatcgtc ggcctacctc cttttgccct gaatgcagtc tatcgctaac
     3121 gcgtagataa aatagtttcc tgtgttatta ctggatgggt gctcgcaaat gtgcccgtca
     3181 ttcagacgat tccagacagt gtttcataat tcctccattt ttctccctta ttggctggct
     3241 acactagtat cattccgcga aacgtttcag gaagagaaac tcttaacgat gaaaggtagt
     3301 tataaatccc gttgggtaat cgtaatcgtg gtggttatcg ccgccatcgc cgcattctgg
     3361 ttctggcaag gccgcaatga ctcccagagt gcagccccag gggcgacgaa acaagcgcag
     3421 caatcgccag cgggtggtcg ccgtggtatg cgttccggcc cattagcccc ggttcaggcg
     3481 gcgaccgccg tagaacaggc agttccgcgt tacctcaccg ggcttggcac cattatcgcc
     3541 gctaatactg ttacggtgcg cagccgcgtg gacggtcaac tgatggcgtt acatttccag
     3601 gaaggccagc aggtcaaagc aggcgattta ctggcagaaa ttgaccccag ccagttcaaa
     3661 gttgcattag cacaaaccca gggccaactg gcaaaagata aagccacgct tgctaacgcc
     3721 cgccgtgatc tggcgcgtta tcagcaactg gcaaaaacca atctcgtctc ccgtcaggag
     3781 ctggatgccc aacaggcgct ggtcagtgaa accgaaggca ccattaaggc tgatgaagca
     3841 agcgtcgcca gcgcgcagtt gcaactcgac tggagccgca tcaccgcacc agtcgatggt
     3901 cgcgttggtc tcaagcaggt tgatgttggt aaccaaatct ccagtggtga taccaccgga
     3961 attgtggtga tcacccagac gcatcctatc gatttagtct ttaccctgcc ggaaagcgat
     4021 atcgctacta tagtgcaggc gcaaaaagcc ggaaaaccgc tggtggtaga agcctgggat
     4081 cgcaccaatt cgaagaaatt aagtgaaggc acgctgttaa gcctcgataa ccaaatcgat
     4141 gccacaaccg gtacgattaa agtgaaagca cgctttaata atcaggatga tgcgctgttt
     4201 cccaatcagt ttgttaacgc gcgcatgtta gtcgacaccg aacaaaacgc cgtagtgatc
     4261 ccaacagccg ccctgcaaat gggcaatgaa ggccattttg tctgggtgct gaatagcgaa
     4321 aacaaggtca gcaaacatct ggtgacgccg ggcattcagg acagtcagaa agtggtgatc
     4381 cgtgcaggta tttctgcggg cgatcgcgtg gtgacagacg gcattgatcg cctgaccgaa
     4441 ggggcgaaag tggaagtggt ggaagcccag agcgccacca ctccggaaga gaaagccacc
     4501 agccgcgaat acgcgaaaaa aggagcacgc tcctgatgca ggtgttaccc ccgagcagca
     4561 caggcggccc gtcgcgcctg tttattatgc gtcctgtcgc caccacgctg ctgatggtgg
     4621 cgatcttact cgccgggatt atcggttatc gcgccctgcc cgtttcggcg ctgccggaag
     4681 tggactatcc gaccattcag gtggtcacgc tctacccagg tgccagcccg gatgtcatga
     4741 cctctgccgt taccgcgccg ctcgaacgcc agttcgggca gatgtctggc ctgaaacaga
     4801 tgtcgtcgca aagttccggc ggtgcgtcag ttatcacttt gcagttccag ctaacattac
     4861 cgctcgatgt cgccgagcag gaagtgcagg ccgcgattaa cgctgcgacc aacttgttgc
     4921 cgagcgatct gcctaacccg ccggtttaca gcaaagtgaa cccggcagat ccgccgatca
     4981 tgacgctcgc cgtcacctca accgccatgc cgatgacgca agtggaagat atggtggaaa
     5041 cccgcgtcgc gcagaaaatc tcgcagattt ccggcgtcgg cctggtgacg ctttccggcg
     5101 gtcagcgtcc ggctgttcgc gtcaaactta acgctcaggc gattgccgcc ctcggcctga
     5161 ccagcgaaac cgtgcgcacc gccattaccg gcgctaacgt taactcggca aaaggtagcc
     5221 tcgacggccc ttcccgtgcg gtcacgcttt ccgcgaacga ccagatgcaa tccgccgaag
     5281 agtatcgcca gctaatcatc gcctaccaga acggcgcgcc aattcgtctg ggcgatgtcg
     5341 caactgtaga gcaaggtgca gaaaacagct ggctcggcgc gtgggcgaac aaagaacagg
     5401 ccattgtgat gaatgttcag cgccagcccg gtgctaacat tatctccacc gccgacagca
     5461 ttcggcagat gctgccacag ctcactgaga gtctgccgaa atcggtgaag gtgacagtgc
     5521 tttccgatcg caccaccaat atccgcgcat ccgtcgatga tactcagttt gaattgatga
     5581 tggctatcgc gctggtagtc atgattatct acctgttttt gcgcaatatt ccggcgacca
     5641 tcattcccgg tgttgctgta ccgctgtcgt taatcggcac tttcgcggtt atggtatttc
     5701 tcgatttttc aatcaataac ctgacactga tggcgttaac tatcgccacc ggattcgtgg
     5761 tcgatgacgc catcgtggtg atcgaaaaca tttcccgcta tatcgaaaaa ggcgaaaaac
     5821 cgttggcggc ggcgctcaag ggcgcaggtg aaatcggctt taccattatc tcgctgacct
     5881 tctcactgat tgcggtgttg atcccactgc tgtttatggg cgatatcgtc gggcgactgt
     5941 tccgcgaatt tgctattacc ctggcggtag cgattttgat ctcagcggtg gtgtcgctga
     6001 ccctgacacc gatgatgtgc gcgcggatgc tcagccagga gtcgttgcgt aaacagaacc
     6061 gcttctcccg tgcctcggaa aaaatgttcg acaggataat cgccgcctat ggtcgtggac
     6121 tggcgaaagt gctgaatcat ccgtggctga ccttaagcgt ggcactcagc acgctgctgc
     6181 ttagcgtgct gctgtgggtg ttcattccga aaggtttctt cccggtacag gacaatggca
     6241 ttattcaggg cactttgcag gcaccgcaat ccagctcctt tgccaatatg gcccagcgac
     6301 aacgccaggt cgcggacgtg attttgcagg atccggcagt gcaaagcctg acctcatttg
     6361 ttggcgttga tggcactaac ccgtcgctga acagtgcacg tttacaaatc aacctcaaac
     6421 cgttggatga acgtgatgat cgggtgcaaa aagtcatcgc ccgtctgcaa acggcggtag
     6481 ataaagtgcc gggcgtcgat ctcttcctgc aaccaacgca ggatctgact attgatactc
     6541 aggtcagccg cacccagtac cagtttacct tgcaggccac gtcactggat gcgctcagta
     6601 cctgggtgcc acagttgatg gaaaaactcc agcaactgcc acagctttct gatgtctcca
     6661 gcgactggca ggacaaaggg ctggtggcgt atgtcaatgt tgatcgcgac agcgccagcc
     6721 gtctggggat cagcatggcg gatgtcgata acgccctgta caacgcgttt ggtcagcggc
     6781 tgatttccac tatttatact caggccaacc agtatcgcgt ggtgctggag cacaacaccg
     6841 aaaatacccc aggcctcgcg gcgctggata ccattcgcct gaccagcagc gacggcggcg
     6901 tggtgccgct aagctcaatt gccaaaattg agcagcgttt tgcgccgctc tccatcaacc
     6961 atctggatca gttcccggta acgaccatct cctttaacgt gccggataac tattcgctgg
     7021 gcgatgcggt gcaggcgatt atggacaccg aaaagacgct gaatctgccg gtggatatca
     7081 ccacgcagtt ccagggcagc accctcgcct tccagtcggc gctgggcagc actgtctggc
     7141 tgattgtcgc ggcggtggtg gcgatgtata tcgtgctcgg cattctgtac gagagcttta
     7201 ttcacccgat caccattctc tcgacgctac ccaccgcagg ggttggcgca ctgctggcgt
     7261 tgctgattgc tggtagcgaa ctggatgtga ttgcgattat cggcattatt ttgctgatcg
     7321 gtatcgtgaa gaagaacgcc atcatgatga tcgacttcgc gctggctgcc gagcgcgagc
     7381 aaggcatgtc gccgcgcgag gcaatctacc aggcttgtct gttgcgtttt cgtccgatcc
     7441 tgatgaccac cctggcggct ctgcttggcg cgctgccgct gatgttgagt accggggtcg
     7501 gcgcggaact gcgtcgtccg ttaggtatcg gcatggtcgg cggcctgatt gtcagccagg
     7561 tgctgacgct gttcaccacg ccggtgattt atctgctgtt cgaccgcctg gcattgtgga
     7621 ccaaaagccg ctttgcccgt catgaagagg aggcgtaagt gaagtttttt gccctcttca
     7681 tttaccgtcc ggtggcgacg attttactgt cggttgccat taccctgtgc ggcatactgg
     7741 gcttccgtat gctgccggtc gccccgctgc cgcaggtcga ttttccggtg attatggtca
     7801 gcgcctcgct gcccggtgcg tcaccagaaa caatggcgtc ttccgttgcc acgccgctgg
     7861 agcgctcact tgggcgcatt gccggagtca gtgaaatgac ctccagcagt tcgctcggca
     7921 gcacgcgtat tattttgcag tttgattttg accgggatat caacggcgca gcgcgtgatg
     7981 tgcaggcggc gatcaacgct gcacaaagtt tgctgcccag tgggatgccc agccgcccga
     8041 cctatcgcaa agcgaacccg tcggatgcgc caattatgat cctcacgctg acgtccgata
     8101 cttattcgca gggtgaactg tacgatttcg cctcgacgca gctggctccg acgatttcgc
     8161 aaatcgacgg tgttggtgat gtcgatgtcg gaggcagctc actgcccgcc gtacgcgtcg
     8221 ggctgaatcc gcaggcgctg tttaatcagg gcgtgtcgct ggacgacgta cgcaccgccg
     8281 tcagcaatgc caacgtgcgt aaaccgcagg gcgcgctgga agatggcact caccgctggc
     8341 agatccagac caatgatgag ctaaaaaccg ccgctgaata tcagccgttg attattcact
     8401 acaacaacgg cggcgcggtt cgtctgggcg atgtggcgac ggtgaccgac tcagtgcagg
     8461 atgtgcgcaa cgccgggatg accaacgcca aaccggctat tttactgatg atccgcaaac
     8521 tgccggaagc caatattatc cagacggttg acagcatccg ggcaaaatta ccggagttgc
     8581 aggaaaccat tccggcggcg attgatctgc aaattgccca ggatcgctcc cccaccattc
     8641 gcgcctcgct ggaagaagtc gagcaaacgc tgattatctc ggtggcgctg gtgattctgg
     8701 tggtgttttt attcctgcgc tcgggtcgcg ccactattat tcccgccgtt tcggtgccgg
     8761 tttcgctgat tggtacgttt gcggcgatgt acctgtgcgg attcagtctc aataaccttt
     8821 cgttaatggc gctcaccatc gctactggtt tcgtggtgga tgacgccatc gtggtgctgg
     8881 aaaacattgc acgtcatctg gaagcgggaa tgaaaccgtt gcaagccgca ctgcaaggta
     8941 ctcgcgaagt cggttttacg gtgctgtcga tgagtctgtc actggtggcg gtgttcctgc
     9001 cgctgctgtt gatgggcgga ttgccgggcc gactgttacg cgaatttgcc gtgacgcttt
     9061 ctgtcgccat tggtatatcg ttgctggttt ctctgacatt aacgccaatg atgtgtggct
     9121 ggatgctgaa agccagcaag ccgcgcgagc aaaagcgact gcgtggtttt ggtcgcatgt
     9181 tggtagccct gcaacaaggc tacggcaagt cactgaaatg ggtgctcaat catacccgtc
     9241 tggtgggcgt ggtgctgctt ggcaccattg cgctgaatat ctggctgtat atctcgatcc
     9301 cgaaaacctt cttcccggag caggacactg gcgtgttgat gggcgggatt caggcggatc
     9361 agagtatttc gtttcaggcg atgcgcggta agttgcagga tttcatgaaa attatccgtg
     9421 acgatccggc agtggataat gtcaccggct ttacaggcgg ttcgcgagtg aacagcggga
     9481 tgatgtttat caccctcaag ccacgcgacg aacgcagcga aacggcgcag caaattatcg
     9541 accgtctgcg cgtaaaactg gcgaaagaac cgggggcgaa tctgttcctg atggcggtac
     9601 aggatattcg cgttggtggg cgtcagtcga acgccagcta ccagtacacg ttgttatccg
     9661 acgacctggc ggcactgcga gaatgggagc cgaaaatccg caaaaaactg gcgacgttgc
     9721 cggaactggc ggacgtgaac tccgatcagc aggataacgg cgcggagatg aatctggttt
     9781 acgaccgcga caccatggca cggctgggaa tcgacgtaca agccgccaac agtctgttaa
     9841 ataacgcctt cggtcagcgg caaatctcga ccatttacca gccgatgaac cagtataaag
     9901 tggtgatgga agtggatccg cgctataccc aggacatcag tgcgctggaa aaaatgttcg
     9961 ttatcaataa cgaaggcaaa gcgatcccgc tgtcgtattt cgctaaatgg caaccggcga
    10021 atgccccact atcggtgaat catcagggat tatcggcggc ctcgaccatt tcgtttaacc
    10081 tgccgaccgg aaaatcgctc tcggacgcca gtgcggcgat cgatcgcgca atgacccagc
    10141 ttggtgtgcc ttcgacggtg cgcggcagtt ttgccggcac ggcgcaggtg ttccaggaga
    10201 cgatgaactc gcaggtgatc ctgattatcg ccgccatcgc cacggtgtat atcgtgctgg
    10261 gtatccttta cgagagttac gtacatccgc tgacgattct ctccaccctg ccctcggcgg
    10321 gcgttggagc gctgttggcg ctggagctgt tcaatgcccc gttcagccta atcgccctga
    10381 tagggatcat gctattaatc ggcatcgtga agaaaaacgc cattatgatg gtcgattttg
    10441 cgcttgaagc ccaacggcac ggtaacctga cgccgcagga agctattttc caggcctgtc
    10501 tgctgcgttt tcgcccgatt atgatgacta ccctggcggc gctgtttggt gcgctgccgc
    10561 tgttattgtc gggcggcgac ggctcggagc tgcggcaccc cctggggatc accattgtcg
    10621 gcggactggt aatgagccag ctccttacgc tgtataccac gccggtggtg tatctctttt
    10681 tcgaccgtct gcggctgcgt ttttcgcgta aacctaaaca aacggtaacc gagtaaatga
    10741 cagatcttcc cgacagcacc cgttggcaat tgtggattgt ggctttcggc ttctttatgc
    10801 agtcgctgga caccaccatc gtaaacaccg cccttccctc aatggcgcaa agcctcgggg
    10861 aaagtccgtt gcatatgcac atggtcattg tctcttatgt gctgaccgtg gcggtgatgc
    10921 tgcccgccag cggctggctg gcggacaaag tcggcgtgcg caatattttc tttaccgcca
    10981 tcgtgctgtt tactctcggt tcactgtttt gcgcgctttc cggcacgctg aacgaactgt
    11041 tgctggcacg cgcgttacag ggcgttggcg gcgcgatgat ggtgccggtc ggcagattga
    11101 cggtgatgaa aatcgtaccg cgcgagcaat atatggcggc gatgaccttt gtcacgttac
    11161 ccggtcaggt cggtccgctg ctcggtccgg cgctcggcgg tctgctggtg gagtacgcat
    11221 cgtggcactg gatctttttg atcaacattc cggtggggat tatcggtgcg atcgccacat
    11281 tgctgttaat gccaaactac accatgcaga cgcggcgctt tgatctctcc ggatttttat
    11341 tgctggcggt tggcatggcg gtattaaccc tggcgctgga cggcagtaaa ggtacaggtt
    11401 tatcgccgct gacgattgca ggcctggtcg cagttggcgt ggtggcactg gtgctttatc
    11461 tgctgcacgc cagaaataac aaccgtgccc tgttcagtct gaaactattc cgtactcgta
    11521 ccttttcgct gggcctggcg gggagctttg ccggacgtat tggcagtggc atgttgccct
    11581 ttatgacacc ggttttcctg caaattggcc tcggtttctc gccgtttcat gccggactga
    11641 tgatgatccc gatggtgctt ggcagcatgg gaatgaagcg aattgtggta caggtggtga
    11701 atcgctttgg ttatcgtcgg gtactggtag cgaccacgct gggtctgtcg ctggtcaccc
    11761 tgttgtttat gactaccgcc ctgctgggct ggtactacgt tttgccgttc gtcctgtttt
    11821 tacaagggat ggtcaactcg acgcgtttct cctccatgaa caccctgacg ctgaaagatc
    11881 tcccggacaa tctggcgagc agcggcaaca gcctgctgtc gatgattatg caattgtcga
    11941 tgagtatcgg cgtcactatc gccgggctgt tgctgggact ttttggttca cagcatgtca
    12001 gcgtcgacag cggcaccaca caaaccgtct ttatgtacac ctggcttagc atggcgttga
    12061 tcatcgccct tccggcgttc atctttgcca gagtgccgaa cgatacgcat caaaatgtag
    12121 ctatttcgcg gcgaaaaagg agcgcgcaat gaagttctgg cgacccggta ttaccggcaa
    12181 actgtttctg gcgattttcg ccacctgcat tgtcttgctg atcagtatgc actgggcggt
    12241 gcgtatcagt tttgagcgtg gctttattga ttacatcaag catggtaatg aacagcgatt
    12301 acaactgtta agtgatgcgc ttggcgagca gtatgcgcag catggcaact ggcgcttcct
    12361 gcgcaacaat gatcgctttg tctttcagat cctgcgttca tttgaacacg ataattcgga
    12421 agataaaccc ggcccgggta tgccaccgca cggctggcgt acccagttct gggtggttga
    12481 tcaaaacaac aaagtgctgg ttggtccgcg agcgccgatt ccacctgacg gtacacggcg
    12541 acccattctg gtcaacggtg cggaagttgg cgcggtgatc gcctcccccg ttgagcggtt
    12601 aacgcgcaat actgatatca atttcgataa acaacagcgg caaaccagct ggttgattgt
    12661 cgccctggca acgttactcg cggcacttgc cacttttctg ctggcgcgcg gtttactggc
    12721 accggtaaaa cgacttgtcg atggcacgca caaactggcg gcgggcgatt tcactacccg
    12781 cgtaacgccc accagtgaag atgaactggg caaactggcg caagacttca accagcttgc
    12841 cagcacactg gagaaaaacc agcaaatgcg gcgcgatttt atggccgata tttctcacga
    12901 actgcgtacg ccattagcgg tgctgcgcgg tgaactggaa gccattcagg atggcgtgcg
    12961 taaattcacg ccggagacgg tggcgtcttt acaggcggag gtcggtacac tgaccaaact
    13021 ggttgacgat ctccatcagt tgtcgatgtc tgatgaaggc gctctcgcct atcaaaaagc
    13081 accggtagat ttgatcccac tgctggaagt ggcgggcggc gcatttcgcg aacgattcgc
    13141 cagtcgtggc ctgaaactgc aattttccct gccagacagt attaccgtat ttggcgatcg
    13201 cgaccgttta atgcagttat tcaataactt actggaaaac agcctgcgct acactgacag
    13261 cggcggcagc ctgcaaatct ctgccgggca gcgcgacaaa acggtgcgcc tgacctttgc
    13321 cgacagtgcg ccaggtgtca gtgacgatca gctacaaaaa ttgtttgaac gtttttatcg
    13381 caccgaaggt tcccgcaacc gtgccagcgg cggttccggg ctggggctgg cgatttgcct
    13441 gaacattgtt gaagcacata atggtcgcat tattgctgcc cattcgcctt ttggcggggt
    13501 aagcattaca gtagagttac cgctggaacg ggatttacag agagaagtat gaccgagtta
    13561 ccaatcgacg aaaacacacc gcgtattttg atcgtggaag atgaaccgaa gctggggcag
    13621 ttgctcattg attatctgcg tgctgcgagc tatgcgccga cgcttatcag ccacggcgat
    13681 caggtactgc cgtatgtgcg ccagacacca ccggatctga tcctgttaga tctgatgctc
    13741 cctggcaccg atggcctgac gctgtgccgg gaaattcgtc gtttttctga cattccgatc
    13801 gtgatggtga cggcaaaaat cgaagagatc gatcgcctgc tggggctgga gattggcgca
    13861 gatgattata tctgtaagcc gtacagccca cgggaagtgg tagcgcgcgt caaaaccatt
    13921 ttgcgccgtt gcaaaccgca gcgcgagttg cagcaacagg atgctgaaag cccgttgatt
    13981 atcgacgaag gtcgttttca ggcttcatgg cgcggtaaaa tgcttgacct gacgcctgcg
    14041 gaatttcgtc tgctgaaaac gctctctcac gaaccaggaa aagtgttctc ccgcgagcaa
    14101 ttgctcaatc atctttatga cgactaccgc gtagtaaccg accgcaccat cgacagccac
    14161 attaaaaacc tgcgccgcaa gctggaatct ctcgacgccg aacagtcatt tatccgcgcc
    14221 gtttatggcg tcggttaccg ctgggaagcc gacgcctgcc gcatcgttta gttttagcga
    14281 cattattttg ttagccggag atggcgttca gaccagatcc ggcaacatta tcccacgcat
    14341 ggtcagcaaa ctgacattat ctctccgccc aggcaggcat cagaaaatcg ctcatacttt
    14401 aatcggtaaa cagcaccttt agatgctgtt ttcgatacac aatttcaatc aaggagtcat
    14461 tatggctggt tggtttgaac tcagtaagag cagtgataat cagtaccggt ttgtgctaaa
    14521 agcgggcaat ggtgagacta tcctcaccag cgagctttat acctcaaaag cctctgcgga
    14581 aaagggcatc gcgtcggtgc gtagcaacag cccgcaagaa gaacgctatg agaaaaaaac
    14641 ggcaagtaac ggcaaattct atttcaatct gaaagccgct aatcatcaaa ttatcggctc
    14701 cagccagatg tacgccaccg cgcaatctcg tgaaaccgga attgcctccg ttaaagccaa
    14761 tggcacaagc cagacggtga aagacaatac gtaattacga tgccgggcgt gggttgttgg
    14821 cgtccggcgc tttaccagat ccccccacag cgctacaatg cccgccctta aagtgggggc
    14881 actcccctaa ccgcttcatc aggtgaagcg gatctgacct gtcatcagaa cgagagaatt
    14941 atgtttaaac cggaactcct ttccccggcg ggaacgctga aaaatatgcg ttacgctttc
    15001 gcttatggcg cagatgctgt ttatgcgggc cagccgcgtt actccctgcg tgtgcgcaac
    15061 aacgaattca accacgaaaa tcttcagctc ggcatcaatg aagcccacgc gctggggaaa
    15121 aagttttatg tcgtggtcaa cattgcaccg cacaacgcca agctgaaaac ctttatccgt
    15181 gacctgaaac cggtggtgga aatggggccg gatgcgctga ttatgtccga tccagggctg
    15241 attatgctgg tgcgtgagca cttccctgaa atgccgatcc acctctcggt gcaggctaac
    15301 gccgtaaact gggcgacggt gaaattctgg cagcaaatgg gcctgacccg cgtgatcctc
    15361 tctcgcgagc tgtcgctgga agagattgaa gagatccgca atcaggtgcc ggatatggag
    15421 atcgagatct tcgttcacgg cgcactgtgc atggcctact ccggtcgctg cctgctctct
    15481 ggctatatca acaagcgcga tccgaaccag ggtacctgca ccaacgcctg ccgctgggag
    15541 tacaacgtcc aggaagggaa agaagatgac gttggcaaca tcgtacacaa gtacgagccg
    15601 attccggtgc aaaatgttga gccgacgctg ggtatcggcg cgccaaccga caaagtgttt
    15661 atgatcgaag aagcccagcg tccgggcgag tatatgaccg cgtttgaaga tgagcacggc
    15721 acttacatca tgaactcgaa agatctgcgc gccatcgccc atgtagaacg cctgaccaaa
    15781 atgggcgtgc attcgctgaa aatcgaaggc cgtactaaat ctttctacta ttgcgcacgc
    15841 accgcacagg tttaccgtaa agctatcgat gacgccgctg cgggcaaacc gttcgatacc
    15901 agcctgctgg aaactctgga aggtctggcg catcgtggct ataccgaagg tttcctgcgt
    15961 cgtcatactc acgacgatta tcagaactac gaatacggtt attcagtttc tgaccgccag
    16021 cagtttgttg gtgagtttac cggtgagcgc aagggggacc tcgcggcggt agcggtgaaa
    16081 aataaattct ccgttggcga cagccttgag ctgatgacgc cgcaaggcaa cattaacttt
    16141 acccttgagc acatggaaaa cgccaaaggt gaagcgatgc cggtcgcacc aggcgatggt
    16201 tatactgtgt ggctcccggt cccgcaggat cttgagctca attacgctct gctgatgcgt
    16261 aatttctccg gggaaaccac gcgtaaccca cacggtaagt gattaatttc gattattttt
    16321 cccggatgga aaattcttag aaaccgatca catacagctg catttattaa ggttatcatc
    16381 cgtttcgctg aaaaacataa cccataaaat gctagctgta ccaggaacca cctccttagc
    16441 ctgtgtaatc tcccttacac gggcttattt ttttatgcat aagccctatc tctggtaacc
    16501 gtcttccatt gaccacatcg atagaatcct ccttcatagc acgatgcctt tcacttatcg
    16561 gcatcgtgct cccacaggtt ccggctacgc acagccagaa cgcgcatatt tgacgcttac
    16621 caaaaaatat tctcactctc cacatttgaa tgtcagacga gcgacaccat gtaatcctac
    16681 accttctgtc ttcagctcaa ctatttgcat ttttttgtcc tgagtaacac agaaatgagt
    16741 tgcatcattt tttactatat tttctgcacc agatattcta cccctggcta aagaagcttc
    16801 ggcttcggtg tagtattggt tatcgagttt acgctgaata ttacttttat atgcaaggcc
    16861 aaatttaccg atacttgtct catcattatg cacagcacaa ccagacataa gaaaaacact
    16921 aattaatgat atagcagcta ttttattcac ctc
//
LOCUS       DAPOAV010000093        16188 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.093, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000093 DAPOAV010000000
VERSION     DAPOAV010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16188
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.093"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..256)
                     /gene="nudI"
                     /locus_tag="RN951_003577"
     CDS             complement(<1..256)
                     /gene="nudI"
                     /locus_tag="RN951_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphatase NudI"
                     /protein_id="HDX2528524.1"
                     /translation="MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWALSGGGVESGE
                     RIEEALRREIREELGEQLLLTEITPWTFSDDIRTKTYADGR"
     gene            535..1077
                     /locus_tag="RN951_003578"
     CDS             535..1077
                     /locus_tag="RN951_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528525.1"
                     /translation="MKKIALAGLAGMLLVSASVNAMSISGQAGKEYTNIGVGFGTEST
                     GLALSGNWTHNDDDGDVAGVGLGLNLPLGPLMATVGGKGVYTNPNYGDEGYAAAVGGG
                     LQWKIGNSFRLFGEYYYSPDSLSSGIQSYEEANAGARYTIMRPVSIEAGYRYLNLSGK
                     DGNRDNAVADGPYVGVNASF"
     gene            1177..2379
                     /locus_tag="RN951_003579"
     CDS             1177..2379
                     /locus_tag="RN951_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide deamidase-related
                     protein YfaY"
                     /protein_id="HDX2528526.1"
                     /translation="MLKVEMLSTGDEVLHGQIVDTNAAWLADFFFHQGLPLSRRNTVG
                     DNLDDLVTILRERSQHADVLIVNGGLGPTSDDLSALAAATAKGEGMVLHEAWLKEMER
                     YFHERGRVMAPSNRKQAELPASAEFINNPVGTACGFAVQLNRCLMFFTPGVPSEFKVM
                     VEHEILPRLRERFSLPQPPVCLRLTTFGRSESDLAQSLDTLQLPPGVTMGYRSSMPII
                     ELKLTGPASEQQAMEKLWLDVKRVAGQSVIFEGTEGLPAQISRELQNRQFSLTLSEQF
                     TGGLLALQLSRAGAPLLACEVVPSQEETLAQTAHWITERRANHFAGLALAVSGFENEH
                     LNFALATPDGTFALRVRFSTTRYSLAIRQEVCAMMALNMLRRWLNGQDIASEHGWIEV
                     IESMTLSV"
     gene            2434..2904
                     /locus_tag="RN951_003580"
     CDS             2434..2904
                     /locus_tag="RN951_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001342598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HDX2528527.1"
                     /translation="MSNPPYGERGVGASVARAARWGRIENYMAQVNDSLCLLVQVESK
                     TALDNLDEILDVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIETSIRRIRAAGKAA
                     GFLAVAPDMAQQCLAWGANFVAVGVDTMLYSDALDQRLAMFKSGKNGPRIKGSY"
     gene            complement(2945..3847)
                     /locus_tag="RN951_003581"
     CDS             complement(2945..3847)
                     /locus_tag="RN951_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HDX2528528.1"
                     /translation="MTESTTSSPHDAVFKTFMFTPETAGDFLEIHLPEPLRKLCNLQT
                     LRLEPTSFIEKSLRAYYSDVLWSVETSDGDGYIYCVIEHQSSAEKNMAFRLMRYATAA
                     MQRHLDKGYDRVPLVVPLLFYHGETSPYPYSLNWLDEFDDPQLARQLYTEAFPLVDIT
                     IVPDDEIMQHRRIALLELIQKHIRDRDLIGMVDRITTLLVRGFTNDSQLQTLFNYLLQ
                     CGDTSRFTRFIEEIAERSPLQKERLMTIAERLRQEGHQIGWQEGMHEQAIKIALRMLE
                     QGIDRDQVLAATQLSEADLAANNH"
     gene            complement(4041..5231)
                     /gene="glpC"
                     /locus_tag="RN951_003582"
     CDS             complement(4041..5231)
                     /gene="glpC"
                     /locus_tag="RN951_003582"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit C"
                     /protein_id="HDX2528529.1"
                     /translation="MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLK
                     DGALYDEALKYCINCKRCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMG
                     SVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSIAAQQAQYK
                     DQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQ
                     AITNVESIREAVGVKGIPVIATSSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWR
                     KLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRKIPGLELTVLDSQCCGIAG
                     TYGFKKENYPTSQAIGAPLFRQIEESGADLVITDCETCKWQIEMSTSLRCEHPITLLA
                     QALA"
     gene            complement(5228..6487)
                     /gene="glpB"
                     /locus_tag="RN951_003583"
     CDS             complement(5228..6487)
                     /gene="glpB"
                     /locus_tag="RN951_003583"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase subunit GlpB"
                     /protein_id="HDX2528530.1"
                     /translation="MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGS
                     LDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYSLLEPQRVLDLACQAQALIAESGAQL
                     QGSVELAHQRVTPLGTLRATWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLR
                     ELDLSVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMI
                     LMPACFGLADDKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPG
                     DEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLD
                     VLQTATRGEWYKGDFFAPQPWQQFGVTTDETLRPSQAGQTIENLFAIGSVLGGFDPIA
                     QGCGGGVCAVSALHAAQQIAQRAGGQQ"
     gene            complement(6477..8105)
                     /gene="glpA"
                     /locus_tag="RN951_003584"
     CDS             complement(6477..8105)
                     /gene="glpA"
                     /locus_tag="RN951_003584"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit A"
                     /protein_id="HDX2528531.1"
                     /translation="MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIAT
                     GATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLS
                     FQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLD
                     AKEHGAVILTAHEVTGLIREGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAE
                     YADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYN
                     EIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIV
                     LLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEP
                     AEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVEN
                     LNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKG
                     VQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL"
     gene            8378..9736
                     /gene="glpT"
                     /locus_tag="RN951_003585"
     CDS             8378..9736
                     /gene="glpT"
                     /locus_tag="RN951_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate transporter"
                     /protein_id="HDX2528532.1"
                     /translation="MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLV
                     RKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLIL
                     AAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSV
                     WNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLP
                     PIEEYKNDYPDDYNEKAEQELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWS
                     PTYLKEVKHFALDKSSWAYFFYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFMTLVTI
                     ATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFG
                     YLGGSVAASAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQKRN
                     GG"
     gene            9741..10817
                     /gene="glpQ"
                     /locus_tag="RN951_003586"
     CDS             9741..10817
                     /gene="glpQ"
                     /locus_tag="RN951_003586"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDX2528533.1"
                     /translation="MKLKLKNLSMAIMMSTIVMGSSAMAADSNEKIVIAHRGASGYLP
                     EHTLPAKAMAYAQGADYLEQDLVMTKDDHLVVLHDHYLDRVTDVADRFPDRARKDGRY
                     YAIDFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRVHTFEEEIEFVQGLNH
                     STGKNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYTGKDDKVYLQCFDADELKRI
                     KNELEPKMGMDLNLVQLIAYTDWNETQQKQPDGSWVNYNYDWMFKPGAMKQVAEYADG
                     IGPDYHMLIEETSQPGNIKLTGMVQDAQQNKLVVHPYTVRSDKLPEYTTDVNQLYDAL
                     YNKAGVNGLFTDFPDKAVKFLNKE"
     gene            complement(10859..11098)
                     /locus_tag="RN951_003587"
                     /pseudo
     CDS             complement(10859..11098)
                     /locus_tag="RN951_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311149.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            11280..11930
                     /gene="inaA"
                     /locus_tag="RN951_003588"
     CDS             11280..11930
                     /gene="inaA"
                     /locus_tag="RN951_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide kinase InaA"
                     /protein_id="HDX2528534.1"
                     /translation="MAVSAKYDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKL
                     YVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALL
                     VTEDMAGFISIADWYAQHAVLPYSDEVRQAMLKAVALAFKKMHSINRQHGCCYVRHIY
                     VKTEGNAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM"
     gene            complement(11984..12238)
                     /gene="yfaE"
                     /locus_tag="RN951_003589"
     CDS             complement(11984..12238)
                     /gene="yfaE"
                     /locus_tag="RN951_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like diferric-tyrosyl radical
                     cofactor maintenance protein YfaE"
                     /protein_id="HDX2528535.1"
                     /translation="MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGS
                     CRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDIEIEM"
     gene            complement(12238..13368)
                     /gene="nrdB"
                     /locus_tag="RN951_003590"
     CDS             complement(12238..13368)
                     /gene="nrdB"
                     /locus_tag="RN951_003590"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="HDX2528536.1"
                     /translation="MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQ
                     LSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISI
                     PELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDE
                     LIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFA
                     FAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDL
                     FVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIP
                     WINTWLVSDNVQVAPQEVEVSSYLVGQIDAEVDTDDLSNFQL"
     gene            complement(13457..15742)
                     /gene="nrdA"
                     /locus_tag="RN951_003591"
     CDS             complement(13457..15742)
                     /gene="nrdA"
                     /locus_tag="RN951_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="HDX2528537.1"
                     /translation="MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELR
                     SHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPAL
                     YDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNR
                     VTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTP
                     TRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHT
                     GCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMD
                     YGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQR
                     VKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLN
                     DVNDENGEIALCTLSAFNLGAINSLDELEELAILAVRALDALLDYQDYPIPAAKRGAM
                     GRRTLGIGVINFAYYLAKHGVRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACP
                     WFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSET
                     SSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLV
                     GIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAED
                     AQDDLVPSIQDDGCESGACKI"
BASE COUNT         3777 a         3983 c         4389 g         4039 t
ORIGIN      
        1 tgcgaccatc tgcatacgtc ttggtgcgaa tatcatcgct gaaggtccac ggcgtgattt
       61 ctgtcaaaag cagctgttct cccagttctt cgcgaatttc gcggcgtagt gcctcttcaa
      121 ttcgttcgcc agactccacg ccgccacccg aaagcgccca ttgaccgggg aaaacgccgc
      181 gatcgtcggc cattttacac agcaaataag caccatcatt ttgaatcaaa gggcatacaa
      241 tagtccgttg tcgcataggg gtattcctta taaataaaaa gaaaccatga gaatacggta
      301 actcagaaat atgtgaaagt gacagtaatc tcttttgcaa tgataactgc acttattatt
      361 atttttgtgt gtatcggtaa agtgtgttta ttttttcggc gtttaattat ttaagaagta
      421 tttagttaca ataagtgact agatcccttt tttcgctcat tgaatcctct gtgccaggca
      481 gtacaatccc gcagctttgg gaattttgat taattgcttg tgggaaaggg gataatgaaa
      541 aaaattgcgc tagcaggtct ggccggaatg ctgttggttt ctgcatcggt caatgcaatg
      601 agcatcagcg gccaggcggg taaagaatac accaatattg gtgtcggttt tgggactgaa
      661 tcgacgggcc tggctttaag cggtaactgg acacataacg acgacgacgg tgacgtcgcg
      721 ggcgtggggc tggggttgaa tctgcctctc gggccgttaa tggcgaccgt tggcggaaaa
      781 ggcgtttaca ccaacccgaa ttacggcgat gaaggttatg ccgcagcggt aggaggtggt
      841 ttgcagtgga aaattggcaa cagcttccgt ttgtttggcg agtattacta ctctccggat
      901 tcgctctcca gcggtattca aagttatgag gaagcgaatg ctggcgcgcg ttacaccatt
      961 atgcgtccag tcagtattga ggcgggttat cgctacctga atctgtcggg taaagacggt
     1021 aaccgcgaca acgccgtggc tgacggcccg tatgttgggg ttaacgccag tttctgatcc
     1081 cttccggcgc ggcattctgt cgcgccattc agtttcttac tacgccttat ctccctttgc
     1141 gttatagtga ttcgataaca aaagcaggag ataaccatgt taaaagtgga aatgctatcc
     1201 accggggatg aagtgttaca cgggcaaatc gttgacacta acgctgcctg gctggccgat
     1261 tttttctttc atcaggggct gccattatct cgccgcaata cggtggggga taaccttgat
     1321 gacttagtca ccattcttcg cgaacgtagt cagcacgccg atgtgctgat cgttaacggc
     1381 gggctgggac cgaccagcga tgatttaagc gcactcgccg ctgcgacagc aaaaggtgaa
     1441 ggcatggtgc tgcatgaagc ctggctcaaa gagatggaac gctatttcca cgaacgtgga
     1501 cgagtaatgg caccgagcaa ccgtaaacaa gcggagctgc ctgccagtgc tgaatttatc
     1561 aataacccgg taggcaccgc ctgtggtttt gccgtgcagc ttaatcgttg cctgatgttc
     1621 tttactcccg gcgtaccgtc agaatttaag gtgatggtcg agcacgaaat cctgccgcgt
     1681 ctgcgcgagc gtttttcttt accacagccg ccggtttgtc tgcgtttaac tacctttggt
     1741 cgttcggaaa gcgatctggc acaaagcctg gacactctac aactgccgcc gggcgtaaca
     1801 atgggctatc gctcttcaat gccgattatc gaactgaaac tcaccggacc ggcaagcgag
     1861 caacaggcga tggaaaaact gtggctggac gttaaacgtg ttgccggaca gagcgtgatt
     1921 ttcgaaggca ccgaaggact gcccgcgcag atcagtcgcg aattgcaaaa ccgccagttc
     1981 agcctgacgt tgagcgagca attcaccggc ggtttattgg ctttgcaact ttctcgcgca
     2041 ggtgctccat tgctggcgtg tgaagtggtt ccttcacagg aagaaaccct ggcgcaaact
     2101 gcgcactgga ttacagaacg gcgggccaac cattttgccg ggctggcact ggctgtttcg
     2161 ggtttcgaga acgagcatct caactttgcg ctagccacgc cagacggcac tttcgctctg
     2221 cgtgtgcgtt tcagcactac acgctacagc ctggctatcc gtcaggaagt gtgcgcaatg
     2281 atggcactga atatgctgcg ccgttggtta aacggccagg atatcgccag tgagcatggc
     2341 tggattgagg ttattgagtc catgacctta tctgtctgat tccgccactc tgtgccggtt
     2401 tactgcaccg gcacattccc cctccggcaa aacttgtcca accctcccta cggtgagcgt
     2461 ggtgttgggg ccagtgtggc acgggctgcg cgctggggac gcattgagaa ttacatggcg
     2521 caagttaacg attcactttg tctgttggtg caggtggaaa gtaaaacggc actggataac
     2581 ctggacgaaa tcctcgacgt cgaagggatt gatggcgtgt ttattggacc tgcggatctt
     2641 tctgcgtcgt tgggctaccc ggataacgca gggcacccgg aagtgcagcg aattattgaa
     2701 accagtattc ggcggatccg tgctgcgggt aaagcggctg gttttctggc tgtggctcct
     2761 gatatggcgc agcaatgcct ggcgtgggga gcgaactttg tcgctgttgg cgttgacacg
     2821 atgctctaca gcgatgccct ggatcaacga ctggcgatgt ttaaatcagg caaaaatggg
     2881 ccacgcataa aaggtagtta ttgatatcaa aggcccatgg ggatcggctg tgggcctgtg
     2941 ttaattagtg gttattcgct gccagatcgg cttcgcttag ctgggtggcc gcgagcacct
     3001 ggtcacgatc aatgccctgt tccagcatgc gcaaagcaat tttaatggct tgttcatgca
     3061 taccttcctg ccagccaatt tgatgccctt cctgccgtag ccgttcagca atagtcatta
     3121 atctctcctt ttgtagtggt gaacgttcgg caatctcctc aataaaacgg gtgaaacggg
     3181 aggtatcgcc gcattgcagc agataattaa acagtgtttg tagctggctg tcattagtga
     3241 agcctctaac caaaagcgtg gtgatcctgt cgaccatgcc gattaaatcg cggtcgcgaa
     3301 tatgcttttg aatcagttcc agcagagcta tacgccgatg ttgcatgatc tcatcgtcag
     3361 gtacgatggt gatatccacc aacggaaaag cttcggtgta caactgccgg gcaagttgcg
     3421 gatcgtcaaa ctcatccagc cagttaagtg agtacgggta gggcgatgtt tcgccatgat
     3481 aaaacagcaa tggcaccacc agcggaactc tgtcatagcc tttatccagg tgacgctgca
     3541 tggcggcagt ggcatagcgc attagccgaa aagccatatt cttttctgca gagctttgat
     3601 gttcaatcac gcagtagata tagccgtcac cgtcgctggt ttccacggac cacaaaacat
     3661 ccgagtagta agcgcgtaaa cttttttcaa taaaactagt gggttccagg cgtaaggttt
     3721 gcaggttgca aagcttgcgc agtggttctg gtaaatgtat ttcgagaaaa tcccctgcgg
     3781 tttcgggtgt gaacataaag gttttaaaca ccgcatcatg cggggaggat gttgttgatt
     3841 cggtcatggt tgtccgtcac ctgatattta tgatgacgcg acattacgtc tatcccgggc
     3901 ctttgacatc tgtcagtttc agcctttgcg agacattttc agaggaattt tcaaagcgtt
     3961 gcaacgcata catggtgcgt ggaatcgcgc tcgcaaaaat gcccgataag caatgtgctt
     4021 accgggcatc aaaaggtcgg ttaagccagc gcctgggcca gtagcgtaat cggatgttcg
     4081 cagcgaaggc tcgtggacat ctcaatctgc catttgcagg tttcgcagtc ggtgatgacc
     4141 agatccgcgc cgctctcttc tatctggcgg aacagtggcg caccgatggc ttgtgaggtg
     4201 gggtagttct cttttttgaa accgtaagta cccgcaatac cgcagcactg ggaatccagc
     4261 accgttaact caagccccgg gattttacgc aacagctcca gggtgtagag cgtccagccc
     4321 attttttcca tatggcacgg agtgtgataa accactttca gcggcagcgg tttcagcggt
     4381 aacgttttgc cttcgtccag cttgcgccac agccagcggg ttgccagttc gatatgatcg
     4441 cgcaagcctt tgttgtcgac attcagcact tccgggtatt cgtcgcgcag ggcaaatgta
     4501 caggttgagg aggtggcaat caccggaatg ccttttactc ccacagcttc gcggatcgac
     4561 tctacattcg taattgcctg tttgcgtgct ttatcggtaa agccgttggc gattagcggt
     4621 acgccgcagc atttttcttt gctgagcagt tgtacaccgg tacccattgc gttgagcact
     4681 ttaattaaat ctttacctaa ctgcggatgg ttgtagttaa cgaagcagcc gtgaaagaaa
     4741 gcgacctggt ctttatattg tgcttgctga gccgctatgc tgcgatacca gcgacggaac
     4801 gtgccgaagg agtatttcgg tagcgtgcgg cgatgatcga tttttaacgc cgcatcaagc
     4861 agctgccgca ccggtttcag cgaggtagcg gtgttgacga ttggtgcgaa cggcgtggaa
     4921 acgctaccca tcaggtcggt atgactcaac acaaaattac gcagcgacgg gcgcgtggtg
     4981 tcatattttg cccgcgcgcg ctggataata tcgccaatct tcacatcgga cgggcaggcg
     5041 acttcacaac gtttgcagtt gatgcaatat ttcagcgcct cgtcatacag tgcgccatct
     5101 ttcaaacgca gacgctcgcc atccggcccg gcttgttttg gccctggata accgggattc
     5161 acccggctca ccgggcaggc ggtggtgcag acggtgcact taatgcagtt ttcgaagctg
     5221 gtgtcgttca ttgttggcct cctgcgcgtt gggcaatctg ttgagcggca tgtaaagcac
     5281 tgacggcaca aacaccgccg ccgcatccct gggcgatggg atcaaatccg cccagcaccg
     5341 aaccgatggc aaacaggttc tcaatggttt gccctgcctg cgacgggcgt agcgtctcat
     5401 cagtggttac accgaactgc tgccacggtt gcggcgcaaa aaaatcgccc ttataccatt
     5461 caccccgcgt ggcggtttgt agcacatcaa ggccgagaat cggctcgcga atgccgttac
     5521 gttccgctac cagtccgcca ctaaagaaac tgccgctggc gagaaccgcg aaacgtggac
     5581 gtagcggaat atcggcgtga ttgcgggtcc agatttcatt cactacgcca tttttacagg
     5641 tcactttttt cacttcatcg cccggcatcc acacgccacc ctggcgcaca aactggcgct
     5701 gtaactggtt ttgcagacga atgcccagca cggaaggcgg cagcgttggc aaaagcatca
     5761 gtgaacaagg tagtttttca ttcaaccaac gccacagttt gtcatcggcc aggccgaagc
     5821 aggcgggcat caggatcatt tcgcaggtat tggcgacagg aataagcgca tcaagtaaca
     5881 gcggccagtt ttcttcatta tcaaggaaac gggcgatatt cacagcgcga aattcggtgg
     5941 cgttattgcg caggacatcc agttccggca gctctatttc tgcggtttca accgaaagat
     6001 ccagttcgcg caacgaagcc gccgcaagat gcgcctggaa atccatcagc ccgcttatcc
     6061 ccactacaca tatcttcttc gcgggtagcg gccagacggg aacttctggc gaacttaacc
     6121 aggttgcacg caaagtgccg agcggggtaa cgcgctgatg ggccagttcc acgctgccct
     6181 gcaattgcgc accgctttca gcgatcaatg cctgcgcctg gcaagcgaga tcgagcacgc
     6241 gttgtggttc gagaagactg taaggatggg ctggtgcctg ctgacgcaaa gattccagtc
     6301 cactgtgaat gtctgtcacc ggttgaccat caggcagatg gctcagcaaa tccagcgaac
     6361 cggatgagaa atgcagcgcg ctttgaccac gcgtgacaat ggcacagcgc aggccgtgtt
     6421 tttgcagttg caggccacag agtaatccgg cgaggccgcc gcccataatg acagtatcaa
     6481 agcgcatctt tctgctcctt ctccagacca cacagtccct gataaaccca gcgggtaaat
     6541 tcgctttcgc gcagtgcgtc tccccaggcg atgggttgca cgcctttcca gcgttcgtta
     6601 aggaaggtgg aaagttgctc gatagattgc gcggacgtcg tgacgttaaa ccgttgcagc
     6661 agtccggcag cgcggcaggc gcagagttcg ccctggcagg tgcccatccc cacacgggta
     6721 cgacggcgta aatccagcag gctattaacg tttaaatttt ctaccgcgta ctgcacttca
     6781 cccgcagtta ccgcttcgca ctcacatacc aggctacggt gcagacggcc ttcgctcagc
     6841 caggcaggcg tgcgatcgcc atgacgataa accgcagaac cgcgcagcgg ggcaggcagg
     6901 gagatgactt tacgcaaggt aacttcagcg ggttcttgtg aaccaggcag tgccagatcg
     6961 gcagtcgtac aggggcgcgt gttgcccagt ttgcggcata ccgcgtcggt agcccattca
     7021 gccatcagcc gataggtcat cagtttgcca ccggtgatgg tgataaatcc gtccagacca
     7081 tcgcgttcag catggtcgag cagcacgatg ccacggctga cgttacgtcc gctcgggtcg
     7141 tcatcgctgg caaccagcgg gcgcacgcca gaataggccc gcaaaatgcg cgttttcgcc
     7201 atcacggggg ccagtttttc cccttcacgc agcagaatat caacctcttc tgccgtcact
     7261 cgattatcgt caatctcgtt gtaatcaata cgtaaagagg tggtaccaat cagcgaaatg
     7321 gtatcgccag gcaccagaat atcggcgtcg gaaggtttac ggcagcggtt gatcacatgc
     7381 tggttaatgc ggtgatccat gatcagcagc gatcctttcg ccgggaacat gcgaatgcgc
     7441 agatcggcat attcggcaat gtgttgcccc cagatcccag cggcattaac cacgacaggt
     7501 gcatgaaggg cctgagtttc gccggtgaga tggttacgta cacgaacacc gcacaccgtc
     7561 gcgccttcac gaatcagccc cgtgacttca tgagcggtaa ggataacggc accgtgttct
     7621 ttggcatcca gcatgtttgc tgcggtcaga cgaaatggat caacggtgcc atccggaact
     7681 ttcaccgcgc caatcagtgc cgggttaacg gcaggttcga taatgcgcgc ttgctgcggg
     7741 tctatagctt ctgcgctgat ccctgcttct tcgcaggcgc gaataaaagt ggcctggaat
     7801 gagaggtcat cttccggcag ggtgataaac aggccgttgg ttggttcaac gcagtgacgt
     7861 gcaatgcgtt tcaggatctg gttttcacta atgcattcgc gggccgattc cgcatcggtt
     7921 accgcatagc gcgcaccgct gtgcagcagg ccgtggttac gcccggtggc accggttgcg
     7981 atgtcgtggc gctcaaccaa aatcacgcgc agcccgcgca gggcacagtc gcgggcaatc
     8041 ccggctcccg ttgcgccgcc gccaatgata atcacgtcac ttgattgcga gtcgcgagtt
     8101 ttcattgtta tccctctgaa gttcgttttt taccatttag ccatagtaaa aacatgaatt
     8161 gtttgatttc gcgcatattc gctcataatt cgaaagtgaa acgtgatttc atgcgtcatt
     8221 ttgaacattt tgtaaatctt atttaataat gtgtgcggca attcacattt aatttatgaa
     8281 tgttttctta acatcgcggc aactcaagaa acggcaggtt ctctcactga atcaggctgt
     8341 taatcataaa taagaccacg ggccacggag gctatcaatg ttgagtattt ttaaaccagc
     8401 gccacacaaa gcgcgcttac ctgccgcgga gatcgatccg acttatcgtc gattgcgctg
     8461 gcaaattttc ctggggatat tctttggcta tgcggcttac tatttggttc gtaagaactt
     8521 tgcgcttgct atgccttatc tggttgagca gggattctca cgcggtgatt taggttttgc
     8581 cctttcgggg atctcgattg cttatggatt ttcgaaattc atcatgggtt cggtatcgga
     8641 tcgctcgaat ccgcgcgttt tcctgcccgc aggtttgatt ctggcggcgg cagtgatgtt
     8701 gtttatgggc tttgtgccat gggcgacgtc gagcattgcg gtgatgtttg tactgttgtt
     8761 cctctgcggt tggttccagg ggatggggtg gccgccgtgt ggtcgtacta tggtgcactg
     8821 gtggtcgcag aaagaacgtg gcggcattgt gtcagtgtgg aactgtgcgc acaacgtcgg
     8881 tggtggtatt ccgccgctgc tgttcctgct ggggatggcc tggttcaatg actggcatgc
     8941 ggcgctctat atgcccgctt tctgcgccat tctggtggca ttattcgcct ttgcgatgat
     9001 gcgcgatacc ccgcaatctt gtggtttgcc gccgatcgaa gagtacaaaa atgattaccc
     9061 ggacgactat aacgaaaaag cggaacagga actgacggcg aagcagatct tcatgcagta
     9121 cgtgttgccg aacaaattgc tgtggtatat cgccatcgcc aacgtgttcg tttatctgct
     9181 gcgttacggc atcctcgact ggtcaccgac ttacctgaaa gaggttaaac atttcgcgct
     9241 ggataaatct tcctgggcct acttcttcta tgagtatgcg ggtattccgg gcaccctgct
     9301 gtgcggctgg atgtcggata aagtcttccg tggcaaccgt ggggcaaccg gcgttttctt
     9361 tatgacactg gtgaccatcg cgactatcgt ttactggatg aacccggcag gtaacccaac
     9421 cgtcgatatg atttgtatga ttgttatcgg cttcctgatc tacggtcctg tgatgctgat
     9481 cggtctgcat gcgctggaac tggcaccgaa aaaagcggca ggtacggcag cgggctttac
     9541 cgggctgttt ggttacctgg gcggttcggt ggcggcgagc gcgattgttg gctacaccgt
     9601 ggacttcttc ggctgggatg gcggctttat ggtaatgatt ggcggcagca ttctggcggt
     9661 tatcttgttg attgttgtga tgattggcga aaaacgtcgc catgaacaat tactgcaaaa
     9721 acgcaacgga ggctaatggc atgaaattga agctgaaaaa ccttagcatg gcgatcatga
     9781 tgagcactat agtcatggga agcagtgcaa tggcggcgga cagcaacgaa aaaatagtca
     9841 tcgcccatcg cggtgccagt ggatatttgc cggagcatac gctgccagca aaagcgatgg
     9901 cgtatgcgca gggagcggat tatctggaac aggatttggt gatgaccaaa gacgaccatc
     9961 tggttgttct gcatgaccat tatctcgatc gtgttactga tgttgccgat cgtttcccgg
    10021 atcgggcgcg caaagacggt cgttactacg cgatagattt cacgctggat gaaattaagt
    10081 cgctgaaatt taccgaaggt ttcgatattg aaaacggtaa aaaagtacag acttatccgg
    10141 ggcgtttccc aatgggtaag tccgacttcc gggtgcacac ctttgaagaa gagattgaat
    10201 ttgttcaggg gttaaatcac tctaccggga aaaatatcgg tatctatcca gaaattaaag
    10261 cgccgtggtt ccatcatcag gaagggaagg atattgcggc aaaaacgctg gaagtgctga
    10321 agaaatatgg ttacaccggt aaggacgaca aagtttattt gcaatgtttt gatgctgatg
    10381 agctgaagcg tattaagaat gagctggaac ccaaaatggg catggatctc aatctggtac
    10441 agctgattgc ctataccgac tggaatgaaa cgcagcagaa acagccggat ggaagctggg
    10501 ttaattacaa ctacgactgg atgtttaagc cgggtgctat gaaacaggtg gcggaatatg
    10561 ccgacggtat cgggccggat taccatatgt tgattgagga aacatcgcag ccgggtaata
    10621 tcaaactcac tggcatggtg caagatgctc agcagaataa actggtagtg catccttata
    10681 ccgtgcggtc agataaactg cctgaataca ctactgatgt gaatcagtta tatgatgctc
    10741 tgtataacaa agcgggtgta aatgggctgt ttactgattt ccctgataag gcagtaaaat
    10801 tccttaataa agagtaatgc tactgcagga tggcgttcat gcgccatcct gtctcacatc
    10861 aaatttttcc attcaccacg agttgttccg tacacgtttg tagtaaaaac agtggactgc
    10921 cttctaccgg cttttcttta gccaacaacg aaatctgtcg atagaaggtt ggttcgtgag
    10981 gaacggaaca caattcacct gcaatgcttt tcagcgttaa ctctggttgt aaggcgatgc
    11041 ctaatccctg tcgaataaac ttcatcgctg tatcctactg attaaattca cattttatct
    11101 actgggcgca ctattagtgg tagtggctgg tggaatctat gcgctgcaaa tgaagggtaa
    11161 aagcggtgtc acgctagtag tggcaaaaga aattcattaa tacgacacgt ttcattaaga
    11221 ttttcctcag gtaaccacct atagtcattg tcgttaataa aaatgacagg cgatagggta
    11281 tggcagtttc agcaaagtac gacgaattta atcactggtg ggcaacagag ggcgactggg
    11341 ttgaagagcc taactatcgc cgtaatggta tgagcggggt gcaatgcgtc gagcgcaacg
    11401 gcaaaaagct gtatgtaaag cgcatgacgc atcatctgtt tcattccgta cgttatccgt
    11461 tcggccgacc aacgattgtc cgtgaggttg cggtaattaa agaactggaa cgggccggtg
    11521 tcatcgtgcc gaagatcgtt tttggtgaag cggtgaaaat tgagggtgaa tggcgagcgt
    11581 tgctggtgac tgaagatatg gcggggttca tcagcattgc tgactggtat gcccagcatg
    11641 cagtattgcc ttattctgac gaagtacggc aagccatgtt gaaagcagtg gcgctggcgt
    11701 ttaagaaaat gcatagcatt aatcgtcagc atggctgttg ttatgttcgc catatctatg
    11761 tgaaaacaga aggtaatgca gaagctggtt ttcttgacct ggagaaaagt cgtcgccgct
    11821 tgcgtcgcga taaagcgatt aatcatgact tccgccagct ggaaaaatat ctggagccaa
    11881 tccccaaagc ggactgggag caggtgaaag cgtattacta cgccatgtaa tcgttgtagg
    11941 ccagataaga cgcataagcg ttgtatctgg cactacaacc aattcacatc tcgatttcaa
    12001 tatcgccttt tgcccggcaa caacagggca aaatttcccc cggctgaata aaggctaacg
    12061 gttcggcaat ccagtcaacc tgacctgcaa ccagacgggt gcgacaggag ccgcagtaac
    12121 cttcgcgaca ctgatactca accgccacat tgtgggattc cagcgccgcc agaagggaag
    12181 ggtgttcatc ctggcacagc agttgtgtgc cagtgatgcg cagggtaacg cgggccatca
    12241 gagttggaag ttactcaaat cgtcggtgtc cacttccgcg tcaatctgcc cgaccagata
    12301 agaactgact tccacttcct gcggagcaac ctgcacgtta tcagacacca gccaggtgtt
    12361 gatccatggg atcgggttgg agcgcgtctg gaacggcaga tccaaaccga ctgcctgcat
    12421 acggatattg gtgatgtatt caacgtactg gcagagaatg tctttattca gaccaatcat
    12481 cgaaccgtcg cggaacagat aatccgccca gtctttctcc tgttgagctg cctgaacaaa
    12541 caggtcatag cactcctgct tacactcttc ggcaatttcc gccatctcag gatcgtccgc
    12601 gccgctgcgc agcagattca gcatatgctg ggtgccggtc aggtgcaggg cttcgtcgcg
    12661 ggcaatcagg cgaataattt tggcgttgcc ttccatcaat tcgcgttctg caaatgcgaa
    12721 ggaacaagca aagctgacgt agaaacgaat cgcttccagc gcgttaacgc tcatcaggca
    12781 gagatacagt tttttcttca gctcgcgcag gctaacggtc acagttttac cgttaacggt
    12841 gtgggtacct tcgcccagca gatgccagta gctggtcatt tcgatcagct catcgtaata
    12901 gctggagatc ccttccgcac gtttctggat ctgctcgttg gtgacgatat cgtcaaacac
    12961 aacagacgga tcgttaacga tattacgaat gatatgagta taggaacggg aatgaatcgt
    13021 ttctgagaac gcccaggttt cgacccaggt ctccagttcc gggatcgaga tcagcggcag
    13081 cagtgccacg ttcgggctac ggccctgaat ggaatccagc agcgtctgat atttcaggtt
    13141 gctgataaag atgtgttttt cgtgttcagg cagtgcctgg taatcgatac ggtcgcgaga
    13201 aacgtcaact tcttccggac gccagaagaa agagagctgc ttttcgatca gcttttcgaa
    13261 gatgtcatat ttttgctgat cgtagcgagc cacgttgacc ggctgaccaa agaacatcgg
    13321 ttctttgagc tgatcatttt tcgtctgtga aaaggtggta tatgccatga gtgtgtcctg
    13381 tggttttatt acccctcacc ctaaccctct cccgcaaggg gagaggggac ggtttggtgc
    13441 aaaggctggg ggattatcag atcttacatg cgccgctttc gcagccatcg tcctggattg
    13501 acggcaccag atcgtcctgc gcgtcttcag cgccgtcacg ggtgttctga taatacagcg
    13561 ttttgacccc gaatttgtag gcggtgagca ggtctttcag caactgctgc atcggcactt
    13621 ttcctgacgg gaaacgtgac ggatcgtagt tggtgttagc agagatcgac tgatcgataa
    13681 atttctgcat gatacctacc agttgcaggt agccatcgtt acccggcatt tcccacagca
    13741 gctcataggc gtcgtgcagg tgctcgtagt ccggcaccac ctggcgcaaa ataccgtctt
    13801 tcgacgcttt gatgctgacg taaccgcgcg gcggttcaat accgttagtg gcgttagaga
    13861 tctgtgaaga agtctctgac ggcatcaggg cagaaagcgt ggagttacgc aggccgtgcg
    13921 ttttgattga ttcacgcaat gcttcccagt cgtaatgcag cggctcatta gcgatggtat
    13981 ccagatcttt cttataggta tcgatcggca ggatcccttt cgcgtaagtg gtttcgttaa
    14041 accacgggca cgcgccttgc tcttttgcca gctcgttaga cgctttcagc aggtaatact
    14101 gaatcgcttc gaaggtttta tgcgtcaggt tgttggcgct gccgtcggag taacgcacac
    14161 cgtgcttcgc caggtagtaa gcgaagttga tcacaccaat acccagcgta cgacgaccca
    14221 tcgctccacg tttggcggcc gggatcgggt aatcctgata atccagcagc gcgtcaagtg
    14281 cacgaaccgc cagaattgct agctcttcca gttcatccag gctattaatt gcgcccaggt
    14341 tgaaagcaga cagcgtacac agcgcgattt caccgttctc gtcgttgacg tcgttcagcg
    14401 gtttggtcgg cagggctatc tccaggcaca ggttagactg acgcactggc gcgatggccg
    14461 gatcaaacgg gctatgggta ttgcagtggt caacgttctg aatatagata cgaccggtag
    14521 acgcacgttc ctgcatcatc agcgagaaca gctcaacggc tttcacacgc tgcttgcgga
    14581 tgctgtcgtc tttctcatat ttggtataca ggcgttcaaa ctcttcctga tcggcgaaga
    14641 atgcgtcgta cagccccggt acgtcggacg ggctgaacag ggtgatatct tcacctttca
    14701 gcaggcgggt atacatcagt ttgttgatct gtaccccgta gtccatatgg cgcacgcggt
    14761 tgccttccac accacggttg tttttcaaca ccagcaggct ttccacttcc agatgccaca
    14821 tcgggtagaa cagcgttgcc gcaccgccgc gcacgccgcc ctgagagcag gatttcaccg
    14881 ctgtctggaa atgtttgtag aacggaatac agccggtatg gaacgcttca ccaccgcgaa
    14941 tcgggctacc cagcgcacga atacgcccgg cgttgatgcc gatcccggca cgctgggaaa
    15001 cgtatttcac aatcgcgctg gaggtagcgt tgatggaatc cagactgtca ccgcactcga
    15061 tcagtacgca ggagctgaac tgacgagtcg gggtacgcac gccggacatg attggcgtcg
    15121 gcagcgaaat tttaaatgtg gaaaccgcgt cgtaaaaacg cttcacatat tgcaggcgcg
    15181 tttcacgcgg gtagttcgag aacaggcacg cggcaaccag aatataaagg aactgggcgc
    15241 tttcgtagat ttcgccggtc acgcggttct gtaccagata tttgccttcc agctgcttaa
    15301 cggcagcata agagaaggtc atatcacggt cgtgatcgat aaacgtgtcc atctgcttga
    15361 actcttcttc cgtgtagtct tccagcagat gattatcgta tttgcccatc tcgaccattt
    15421 tcaccacgtg gtcgtacagc gcaggcggct caaactggcc gtaggctttt ttacgcaggt
    15481 ggaagatcgc caggcgcgcg gcgagatact gataatccgg cgcatcacgg gagatcaggt
    15541 ctgcggccgc cttgataatg gtttcgtgga tgtcagaggt cttgataccg tcataaaact
    15601 gaatgtggga gcgcagctcg acctgggaaa tcgaaacgtt atgcagtcct tctgccgccc
    15661 aatccagaac gcgatggatt ttgtcgagat tgatgcgctc tgtgctaccg tcgcgctttg
    15721 tcaccagcag attctgattc atgtatgtcg tacctgtttt tggaattctt tccgcaatag
    15781 tttcatgcag actacctgta gtacgggaag ctgcttagaa cactatatat agggggtatg
    15841 tttgggattc actgcaagat agtgtgaaaa tggccctctt gcaagtgcat aactttgtgg
    15901 ataactcagg aaggaaaaag tggctttcgc gcaccttagg tcagacaagg tgtccgggaa
    15961 agtcaatggg aagagaaaaa tttgttaaaa ataactgttc ggcgatttct tgaacggcag
    16021 aataggttgg ataaattgat atagatggtt tattaatctt tttgctaatg attgcaaaaa
    16081 ttgatctaag cacgagtcat cacataatct gatgtatcag ttgtggtcaa tatataaacg
    16141 aatgtaagcg attgttgatg tcgaaatggt tgttttctat tcggttat
//
LOCUS       DAPOAV010000094        15529 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.094, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000094 DAPOAV010000000
VERSION     DAPOAV010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15529
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.094"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            11..1273
                     /locus_tag="RN951_003592"
     CDS             11..1273
                     /locus_tag="RN951_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein"
                     /protein_id="HDX2528538.1"
                     /translation="MNDENKVPVPDEAQASPAHAEDDIATLEREARVKREAELLNAQD
                     DEEKDPVQPAVNKLKKRKRGKATAFLAIVAVALIFLAWGGNWVYRNILWQPTEEKKQD
                     TAPQTNKTDYRQRNDLGMSIDTAEEEPEQQDNGQSSAGGTGQAAAPPELNKASFLIRR
                     DGSATTQNQVKTRQQEMTLTSATTTGQQDSSAATPPGQPQNTTAPSQGQSPAPVRRIP
                     YNPDLYIPENTSIPCSLDRRFVSDRAGKLRCTVTTDIWSASGNTKLIEKGTTASLLYR
                     AIAEEGMRHGQGRAFIIATKLRTRQPPYLDIPLVDTSAAGELGEAGVDGWIDSHFWER
                     FGGALMVGMIPDIAAWASNSAGKKDRNTDYTENSRQAMADMARTTLENSINIPPTLHK
                     NQGEIINLITGEDIDFSNIYTLRLKNDR"
     gene            1263..2288
                     /gene="virB11"
                     /locus_tag="RN951_003593"
     CDS             1263..2288
                     /gene="virB11"
                     /locus_tag="RN951_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="HDX2528539.1"
                     /translation="MTAKNISLDRYKQRFFGDFLELPGLTEIAVNRPGELYTKINGVW
                     EQHAVPLNYEDCYNFARCLAKHHGDNIEDIKPGLSATLESGERCQVIVPPACERDTVS
                     ITIRKPSKVQIPHQSYIDAGFYNRVTGEEKTETHDEELIALYNTKNIPLFMEKCVEYG
                     KTLAVAGETSTGKTTYMKMLIGYIPVHLRISTIEDNPEITFFIHKNYVHLFYPSESSD
                     EKGSIVTPASLLRWNYRMNPDRILLTEVRGAEAWDFLKITGSGHEGSMTSIHAGSAKE
                     AIDGFITRCYENPQCAQLPYTFMLRKVLDSLDVIVSIDLDGNVRRMNDIYFRPIHRNQ
                     YFEEMKA"
     gene            2285..2688
                     /locus_tag="RN951_003594"
                     /pseudo
     CDS             2285..2688
                     /locus_tag="RN951_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592251.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Cag pathogenicity island protein Cag12"
     gene            2724..3026
                     /locus_tag="RN951_003595"
     CDS             2724..3026
                     /locus_tag="RN951_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kikA from plasmid origin"
                     /protein_id="HDX2528540.1"
                     /translation="MNKTVIAAAVLCMAAGTPIYSFAADPCEVVLCMYGKATGNSGGS
                     ECRSAEKAFFNIVKKNKHGFLPNHTLNARKAFLGECPSADPEAVNKILSKFGKVRG"
     gene            3071..3376
                     /locus_tag="RN951_003596"
     CDS             3071..3376
                     /locus_tag="RN951_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011172016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dpoa decarboxylase"
                     /protein_id="HDX2528541.1"
                     /translation="MQKEDLFIRNIHSRNQDRISVALIYDTLSKEAHSGCGLYYEIYE
                     SRLIGLLRDHLLELNEADANKLRRYAESKGTKIDDASYSEALEAERECRAEIYREQM"
     gene            4086..5945
                     /locus_tag="RN951_003597"
     CDS             4086..5945
                     /locus_tag="RN951_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HDX2528542.1"
                     /translation="MILNKLAASLSPIVNGMLALLAFVQQQQLVLALLAGLTMPFFAS
                     MKSDERQKAPLWKKLIIAFSLLCFLSGTLAPVVIGPFQWLYKIRPSSDNTVLAWSVRI
                     AFTVTGVIFHIMLRRIFTPELDKIKKRLVKKTTLERELRTDVRTVKSLLPETLHYDPL
                     DYIDLNKGIFTGMDRENEPMYLPLKDWQKQHADIIGTTGAGKGVAAGILLYQSIIAGE
                     GVFVMDPKDDEWAPHLYRKACEDAGKPFALIDLRKQQYQLNLIEDITPDELEELFVAG
                     FSLAEKGQESDFYRIDDRKAARMAAQFVSDNPSATLRDIYNGDYVQGIAEKIKAFFGK
                     IEELALLNAINSPEGFSLKHIFDEGGCCYVVGSMRNSKIITAQRMLLVRLYQLAERRD
                     RVTDVPRPIAVYLSELKYHLSRPALEGLGAARDKGVHIIMDHQSIADLKDCPADLKGD
                     AVVGAVVENAKFKLVYRVMDPDTAGWVARMSGTILVDDELRKAKTDNMLTETIDSERT
                     IRQAERFFIDSNMILNLPDFVSFIFTTKTLPSASLISPIKVRKRQLKIFSVSPDIAAA
                     AAPVKIMLDFGEDDKPAMPDVMTTHPALFFDESEVKPAKSQSDDEEHFSPLDF"
     gene            5955..6701
                     /locus_tag="RN951_003598"
     CDS             5955..6701
                     /locus_tag="RN951_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein MobC"
                     /protein_id="HDX2528543.1"
                     /translation="MLISSYHERQTRNSEKIRQLLNFLKEETYSDFKTLMQLFSFRDH
                     KSLYSLLAKMERMGLIQKHMLESRTIKISLWGITSDGLAAVLTPNDKIFPARFEPSKI
                     TGWTLEHHLDNQAARLILEKKGASGWINGDRASFLSQYQVKHRPDGLLTLPDGNVIAI
                     ETERRLKTRARYQSIIASHLLARTNKYWIYIFYVVPDPQKKRALELLFDSIRHVIINH
                     QHIPLEERHRRVFRIYTFDELKHLSLGSYT"
     gene            complement(6894..7838)
                     /locus_tag="RN951_003599"
     CDS             complement(6894..7838)
                     /locus_tag="RN951_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1738 domain-containing protein"
                     /protein_id="HDX2528544.1"
                     /translation="MTISLHTQTSAPNITAATSVSPLDPSGSSKTKFSKTRADIYQTV
                     TNNIIAALEGGVKPWSCPWQRVSGISGLPSNYATGVAYSGMNIMLLWCSASKQGFSDS
                     RWMTYKQAQVAGGQVRKGEHGTTAIFYTTLEKENDAGEVEHIPMLKTFTVFNVQQIDG
                     LSLTTETVSPEATFDPLPQAENLLRKSGANIIEKGQNAFFSPSTDEVWLPERHLFSDA
                     ANFYATGLHELVHWSGGKKRLNREMKGKFGSADYAEEELVAELGSAFLMADLGIEGEV
                     QHGSYIASWLKALKNDKRYIFKAASAASKAHRYLMDKL"
     gene            8075..8308
                     /locus_tag="RN951_003600"
     CDS             8075..8308
                     /locus_tag="RN951_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001446639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528545.1"
                     /translation="MGVNTAAVILANNHPSGISEPSHAGKVMRVQIKKGLGIVDMRTL
                     AHFTSEVSPRCPSLNGGYFDRRELRPPFCCDLC"
     gene            8844..9839
                     /locus_tag="RN951_003601"
     CDS             8844..9839
                     /locus_tag="RN951_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HDX2528546.1"
                     /translation="MNDAPSDIIFHYPPELFNLLVDVVPLLNRSKQDVLVFFRGAGVP
                     DNITSDIAVHLRAAPKDVNKYQMVRTVLERLNAKGEHALRERREVLRRVVDFANFDSC
                     WPADQLKAKGLVASIREVVNQKDAFTRMNNAREEERQTRLAESQRIAAEKRDRSYRIE
                     NAKQGLYKLFGTTATAQERGKLLETALNNLFQAYGVLIRKSFHLVGEAGEGIVEQIDG
                     IIELSGVLYFVEMKWYRNPVGKPEISEHLVRLMSRAEVRGIFISASDYTEPAILTARE
                     FLQHKVVVLSTLHEIVRLLEQQDDLSEFFTKKVQAAQIHKNPYFCPHDSQAQGAL"
     gene            9836..10924
                     /locus_tag="RN951_003602"
     CDS             9836..10924
                     /locus_tag="RN951_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528547.1"
                     /translation="MTASWMDINKPPSPATAVTAAQVANGPIFPPQQRLLTYSPDEWE
                     GFVEEWAYYCLTTKYEHVLRFSGAGDMGIDVAGFVGDERLLGVWDNFQCKHYGNAIRP
                     SDVWVEFGKIIWYSYKGEYTVPRRYYFVSPRGAGTSLSRLFSNDTKLREELLANWDKH
                     VKNAITSTQEVLLDAKLRAYVDSFDFTIFDAKTALQLVDDHRATPVHTARFGGGLPTR
                     PASEKPPQEVAATESRYVTQLFGAYSEHTGTIVTDPSALPLPKLKDHFRRQREAFYEA
                     ESLRVFARDSVPPGTFEALLDDIHDGVIDTHDGNHADGYEKVCAVTKAARDMQITANA
                     LIICTNPKDRDGICHQLVNEERLRWTRS"
     gene            10921..11415
                     /locus_tag="RN951_003603"
     CDS             10921..11415
                     /locus_tag="RN951_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine transporter"
                     /protein_id="HDX2528548.1"
                     /translation="MSQEHKPITFNSPLEAGIRAVSILGAAYPQTYDLQRLVAFDYLL
                     VHTGDIGGPDNLHPPTPMRSAELLVRRKLVEQSLLLMMTRDLVEREVTSEGIKYGAGE
                     NAATFLSSVSSNYLLSLKDRAVWLVETIGDLTDEQFKAMMRRFFDKWVEQFQSIEQSL
                     GGDA"
     gene            11412..13292
                     /locus_tag="RN951_003604"
     CDS             11412..13292
                     /locus_tag="RN951_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDX2528549.1"
                     /translation="MTTVTPGLRLRFLGFFGPQKPPATVTFGTGLNVIYGASNTGKSF
                     IVEAIDFMLGGKPPLRDIPERVGYDLVLLGLETLDGKSFTLWRSIDGGGFRLYEDLHQ
                     TPPTNEIPYTQLDEKHSDKNNTNLSSFLLDLCSLGGKRVRKNSRNETLSLSFRNIARL
                     MIVDETEITQQSSPLIDGNPTANTPNLATFKLLLTGADDSALVATSNKSEPEELSRKA
                     QLRLLDQLLEDYGDRLKELTKSPKELKEQLEKINTSLRQQAAQVNTTEDEFQEAAGKR
                     RELRKKLEESRERRAEVSAMLERFRLLDRHYLSDIERLRAIEEGGTLFSVLSAGHCPL
                     CGAAPDHHPPDTGCNGDTDAVVQAARVEIAKIEVLRTELVATVQSLEREGANFDRRIP
                     TVVRELESISESVEEFLAPKLSTLRKSYSDFADKRAEVREALALYATVQDMERRRADL
                     EKGTEDEKAGVVTNADLSSTVAHSFAKTVEGILTGWHFPEVGDVYFDSKSRDLVIAGK
                     SRSAFGKGLRAITHAAFTLGLLAFCRERHTPHTGFVVLDSPLLAYREPDGTEYDLTGT
                     DLKDQFYAYLEALPEDTQVIVVENTDPPDAIMKREQSLMFGKNPHHGRYGLFPFIADP
                     AQ"
     gene            complement(13576..14595)
                     /locus_tag="RN951_003605"
     CDS             complement(13576..14595)
                     /locus_tag="RN951_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4917 family protein"
                     /protein_id="HDX2528550.1"
                     /translation="MPHAIMPWAQIAPNYHRNTILLGNGASIAVSPVLDYGSLLAYAH
                     RAGLLTHDMNRLFQFFRTSDFEMILRLVWQASNVNRSLQIPDNRTHQAYLNVRNCLIQ
                     AVRDIHPEYEQVSDKLPNMYQFLKGFDTVLSLNYDLLIYWTMTYGFDIQDGHLFKDCF
                     LWNGIFDDAWWRFRDTFRERTNTLVFYPHGSLALCRNVVEQEFKIHNAGEGLLEAILE
                     EWRSEQAVPLFVSEGTMQQKVSSIQNSYYLSTVYREVLTSQRPSLTILGWGLGEHDRH
                     ILKRMRGTGIQRVAVSVYRWNQVYCNHAYQVIQDDLGPVRVDFFDSESPGCWVHPVQP
                     ILPRF"
BASE COUNT         4024 a         3860 c         3853 g         3792 t
ORIGIN      
        1 aaacatgcag atgaacgacg aaaacaaagt gcctgtgccg gatgaagcgc aggcatcccc
       61 ggcacacgct gaggatgata ttgccacgct tgagcgggaa gcccgcgtaa aaagggaggc
      121 agagcttctc aacgcgcagg acgacgaaga gaaagacccg gtacaacccg ccgttaacaa
      181 gctgaaaaag cgcaaacggg gcaaagcaac cgcctttctt gccattgtcg cggtcgcgct
      241 tatcttcctg gcatggggtg gtaactgggt ttatcgcaat atcctgtggc agcctacgga
      301 agaaaagaaa caggacacag ccccgcagac gaacaaaacc gattaccggc agcgtaacga
      361 tctcggtatg tccatcgata cagccgaaga agagccagag caacaggata acggccagag
      421 cagcgcgggg ggaacagggc aggcggctgc cccgccagaa ctcaacaaag ccagcttcct
      481 tattcgccgt gatggttcgg ccaccacaca gaaccaggta aaaacccggc agcaggaaat
      541 gacgctgaca tcggcaacaa ccaccggaca acaggacagc agcgcggcca cacctcccgg
      601 ccagccgcaa aataccaccg caccgtcgca gggacaaagc cccgcaccag tacggcgcat
      661 accctataac cctgacctgt acatcccgga aaatacctcg atcccctgct cactggatcg
      721 ccgctttgta tctgaccggg cggggaaact tcgctgtacg gtcactactg acatctggag
      781 cgccagcggc aacacgaagc tgatagagaa aggcactacc gcatcattac tttaccgcgc
      841 catagcggaa gaaggtatga ggcacgggca agggcgggca ttcatcattg cgacgaagct
      901 acgcacccgc cagccacctt atctcgatat cccgttggtt gataccagcg cggctggcga
      961 gctgggcgag gctggcgttg atgggtggat agattcgcac ttctgggagc gattcggcgg
     1021 cgcattaatg gttggcatga tccccgatat tgccgcatgg gcatccaaca gcgcaggtaa
     1081 aaaagaccgc aatacggact atacggaaaa cagtcgccag gctatggcag atatggctcg
     1141 taccactctg gaaaacagca tcaatattcc cccaacgctc cataagaatc agggcgagat
     1201 catcaatctg atcacaggcg aggatattga tttttccaac atctatacac taaggttgaa
     1261 aaatgaccgc taagaatatt tccctcgacc gctataaaca acgtttcttt ggcgactttc
     1321 tggagcttcc cggcctgacg gaaatcgccg tcaaccgtcc aggtgaactg tacacaaaaa
     1381 tcaacggcgt gtgggagcaa catgccgttc ctttgaacta tgaggattgc tacaactttg
     1441 cccggtgcct ggcaaaacac cacggcgaca atatcgaaga tattaagccg gggctgtcag
     1501 ccacgctgga atccggcgaa cggtgccagg tgattgttcc tccggcctgt gagcgcgata
     1561 cggtgtctat caccatccgt aagccatcaa aggtacaaat cccgcatcag tcatatatcg
     1621 atgcggggtt ttataaccgg gtaacaggcg aggaaaaaac ggagacgcac gacgaggaat
     1681 taattgcatt gtacaataca aaaaacattc ctttgtttat ggagaaatgc gtcgagtacg
     1741 gtaaaactct cgcggtcgcc ggggaaacca gtacagggaa aactacctat atgaaaatgt
     1801 tgataggtta tattccggta catcttcgga tatcaacaat tgaggacaac ccggaaatca
     1861 cgttctttat ccataaaaac tacgtccatc ttttttatcc gtcagaatca tcagatgaaa
     1921 aaggttctat cgttaccccg gcgagccttt tacgctggaa ttaccgtatg aaccctgacc
     1981 gcattttatt aacagaggtt cgcggtgcgg aagcctggga cttccttaaa ataacaggtt
     2041 ccggccatga agggagtatg acctccattc atgcaggatc agcgaaagaa gctatagatg
     2101 ggtttattac ccgttgctat gaaaatccac agtgcgccca gctcccctat acatttatgt
     2161 tacgtaaggt tctggatagc ctggacgtga ttgtgagcat tgatttagac ggaaatgtcc
     2221 gccgtatgaa tgacatttat ttccgtccaa ttcatcgaaa ccagtatttt gaggaaatga
     2281 aagcatgata aaacaaatta aagtaatcat gttggcagca atagttaccg gatgttcatc
     2341 gccaccgcct cccgttcctg tagattggga taaagccgcc gccccattaa ataccagttt
     2401 accgcaatgg agcgacaata acgttatggt cccttccccg acagttaaca gtaaatggac
     2461 atcatcaatc agcgcacaaa gtttctacaa tacaatacaa tatggactcc agccgtattt
     2521 tacgcagtcg cccactcaac acgaattgtc gtcactgcac aatccggcac tgatttcttt
     2581 aatgccaaaa actggcttcg gcagaatgga gcaaaaggtg ttattgaata ccagcctgtc
     2641 tttaattgtc tgacgtgcag agaaaccact atttatttct ctcgctaatc aatttaagca
     2701 acacaaccta ataaggactc accatgaata aaaccgttat cgcggcggct gtattatgta
     2761 tggccgcagg aaccccaatt tattcctttg ccgctgaccc gtgcgaagtt gttctttgca
     2821 tgtacggaaa agcaacgggt aatagtggtg gaagtgaatg ccgctcagca gaaaaggctt
     2881 tctttaatat agtcaaaaag aataaacatg gtttcttacc taaccatacg ttgaatgcga
     2941 gaaaagcatt tcttggtgaa tgtcccagcg cagacccgga ggcagtaaat aaaatactat
     3001 ctaagttcgg caaggtcaga ggatagtaat aatccgcata acaccccctg tttactgtaa
     3061 aaggtgcaac atgcaaaaag aagacttatt tatccgaaat atacattctc gtaatcagga
     3121 caggatatcg gtagccctga tatatgacac gttatctaaa gaagcccaca gtggttgtgg
     3181 gctgtattat gagatatacg aaagcaggct tatcggtctt ttgcgcgatc atcttttaga
     3241 acttaatgaa gctgacgcaa ataaattacg acgctatgcc gaaagcaaag gcacgaaaat
     3301 tgatgatgcg tcctacagtg aagcactgga agctgaaagg gagtgcaggg ctgaaatata
     3361 ccgcgaacag atgtaatcac acagaacaaa aatgtattgt gcaacacaca ggctgacagg
     3421 cggcgggttt ttaaggcttc attatttttg gcttcaattt cgaagaaatt gttaagacga
     3481 aaaataatga agtggaacgt ggacagaaaa ttcaatttcg gagaaattgc taattttcag
     3541 gatccacgtc cacccgcgaa cattcgcccc agcgaattga agcgggccgg ggggagccgc
     3601 aaaaattttg ccgccccagc gagcaataag gcacgcccac gtgccggttt ttgtgggggg
     3661 cttgccccgc acaccgtcgc agccaggcta tatttcccgc cccggcgggg aatatgccga
     3721 ttaggcgcga ccaacccctt taaagcagcg ttcccatttt ttcgagcttg cgaagaaaaa
     3781 ataggctaaa cgcgcgtctt aaaggggttg gtcgcgcgta gcgtgcgacg gtgtgccgcc
     3841 gttgaccccg ggggttttga cgcgacgttc agccgcgaca ttacccccat gcgacaggca
     3901 ataagggcgt ccagcccgca tgtactggcg cacgccgtgt cgtgcaggaa agcatgcttt
     3961 cctgcacatg gccgcacagc ggccaccttc tttaccccat acgctcgccc cgccttttcg
     4021 cccgacaccg tggggcgaat tgatggggcg atgttatggg gtgaatagct gacgagggag
     4081 gtatcatgat tttaaataag cttgccgctt cactgtcgcc gatagtgaac gggatgctgg
     4141 cgctgctcgc ttttgtgcaa cagcaacaac tggtgctggc gttattagcg gggctgacga
     4201 tgccgttttt tgcgtcgatg aaaagcgatg aacggcagaa agccccgtta tggaaaaagc
     4261 tgattatcgc tttttccctg ctgtgttttc tctccggcac actggctccg gtcgttatcg
     4321 gaccctttca gtggttgtat aagatcagac ccagcagtga taatacggta ctggcttggt
     4381 cagtacggat tgcattcact gtaaccgggg ttatttttca tattatgctt cgccggatat
     4441 tcacgccgga actggacaaa ataaagaaac gccttgttaa aaaaaccacc cttgaacggg
     4501 aattgcgcac cgatgtccgc accgtaaagt ccctgctgcc cgaaacactg cattatgatc
     4561 cgctggatta tatcgacctg aataaaggca tttttactgg catggacagg gagaacgaac
     4621 caatgtatct cccgttaaaa gactggcaga aacagcacgc ggatattatt ggcaccaccg
     4681 gagccggtaa aggggtagct gccgggatat tgctatatca aagtattatt gccggtgaag
     4741 gcgtttttgt tatggacccc aaagacgatg aatgggcacc acacctttac cgcaaagcct
     4801 gcgaggatgc aggaaaaccc tttgccttaa ttgacctgcg aaaacagcaa taccagctaa
     4861 acctgattga agatattacg ccagatgaac tggaagaatt gttcgttgcc ggtttcagcc
     4921 tggcagaaaa agggcaggaa tcggacttct atcgtattga tgaccgaaaa gccgcccgta
     4981 tggccgcgca atttgtcagt gataacccat cggcaactct ccgtgatatt tataacggtg
     5041 attacgttca gggtattgcc gaaaaaatca aagcgttctt tgggaagatt gaggaactgg
     5101 cattactcaa tgccattaac tcaccagaag gcttttcgct taagcacata tttgatgagg
     5161 gcggctgctg ttatgtagtc ggctccatgc gaaacagcaa aattattacc gcccagcgca
     5221 tgctgctggt tcgcctttac cagttagcag aaaggcgcga ccgtgtaaca gacgtacccc
     5281 gccccattgc tgtttatctt tccgaactga aataccattt atccaggcca gcgctggaag
     5341 gtttaggcgc ggcgcgggat aaaggcgtac acattattat ggaccaccag tccatcgccg
     5401 atttaaaaga ctgcccggca gatttgaaag gtgacgccgt tgtcggtgcg gtcgttgaaa
     5461 atgccaaatt caaactggtt taccgggtta tggatccgga tacggcaggc tgggtggcaa
     5521 gaatgtcagg cacgattctg gtggatgacg aactccgcaa ggctaagacg gataatatgc
     5581 tgacagaaac catcgacagt gagcgcacaa tccgccaggc cgaacgtttc tttattgaca
     5641 gcaatatgat cctgaacctg cccgattttg tcagctttat ctttacgaca aaaacgctac
     5701 cttctgcctc cttgatttca ccgataaagg tcagaaagcg tcagctaaaa atcttctcgg
     5761 tttcccctga tattgccgca gcggcagccc cggtgaagat catgctggat tttggcgagg
     5821 atgataaacc agccatgccg gatgtgatga caacccatcc ggctcttttc ttcgacgaaa
     5881 gcgaagtaaa accggcaaag tcccaatctg atgatgaaga acacttctcc ccactggatt
     5941 tttaaggagt ggttatgctg atttcgtcat atcacgagcg ccagacgcgc aacagcgaga
     6001 aaataagaca actgctgaac ttcctgaaag aagaaaccta cagtgatttt aaaacgctga
     6061 tgcagttatt tagcttccga gatcataagt cgctttattc gctgcttgca aaaatggagc
     6121 gaatggggtt aatccagaag catatgcttg aatcacggac aatcaagatt tcattatggg
     6181 ggatcaccag cgacgggctg gcggcggtct taaccccgaa tgataaaatc tttcctgcgc
     6241 ggtttgaacc atcaaaaatc accggctgga cactggagca ccatcttgat aatcaggccg
     6301 ccaggcttat tctggagaag aaaggtgctt cgggatggat taacggcgac cgtgccagct
     6361 ttctcagcca gtatcaggta aaacatcgcc cggacgggtt actgaccctg cctgacggta
     6421 acgttattgc cattgaaacc gagcgccgcc tgaaaacccg agcccgctac cagtcgatta
     6481 tcgccagcca cctgctggcc cgaacaaaca agtactggat ttacattttt tatgttgtgc
     6541 ccgatccaca gaagaagcgt gcgcttgaac tgctgtttga cagtatcagg catgtcatca
     6601 tcaaccatca gcacatcccg ctggaagaac gccaccgtag ggtgtttcgc atttatacct
     6661 ttgatgaact gaaacacctg tcattaggca gctatacgta agcttttact caggccatcg
     6721 tgatggcctc accggcctgg cggcgatacc gccaggccgg aaatttttta ttccactgcg
     6781 agccgcagac tgttcggtac tcgctgtgct gcgttccgcc tcagtctgcg ccttgcagcg
     6841 ttgccggtta taagccatgt aaccgcattc ccttgcggtg tctgattccg gtctcagagt
     6901 ttatccatca ggtaacgatg tgctttagag gctgcgctgg ccgctttgaa aatataacgc
     6961 ttgtcgtttt ttagcgcttt cagccaggaa gcaatatagc ttccatgttg tacctctccc
     7021 tcaatcccaa gatccgccat cagaaaggca cttcccagct ctgctaccag ttcttcctct
     7081 gcataatccg cactgccaaa cttccctttc atttcacggt tcagacgttt tttgccacca
     7141 ctccagtgaa ccagctcatg cagacctgta gcgtagaaat tagccgcatc cgaaaacaga
     7201 tggcgctccg gtagccagac ttcatctgtt gatgggctga aaaaggcgtt ttgtcctttc
     7261 tcgatgatgt ttgcgccact cttccgcaac aggttctcag cctgcggcaa cgggtcaaag
     7321 gttgcttccg ggctgacagt ttcagttgtc agggacaggc cgtcgatttg ctgaacgtta
     7381 aacacggtga aggttttcag catcgggata tgttcaactt ctccggcgtc gttttccttc
     7441 tccagcgtgg tgtaaaaaat agctgttgta ccatgttccc ccttgcgaac ctgtccacct
     7501 gctacctgtg cctgtttgta ggtcatccag cgtgaatcgc tgaaaccctg cttagatgcg
     7561 ctgcaccaca gtaacatgat gttcataccg ctgtaggcta cgccggtggc gtaattcgat
     7621 ggcagaccag atatgccgga tacgcgttgc cacgggcagg accacggttt tacaccgcct
     7681 tcaagtgctg caatgatgtt gttggtaacg gtctgataaa tgtcggctct ggttttagaa
     7741 aatttcgttt ttgaggagcc tgacgggtcc agcggggata cgctggtcgc cgctgtgatg
     7801 ttaggggcgc tagtctgggt atgcagggaa atcgtcatgg ttttttctcc gtcagtgtgt
     7861 gattttcgtc ttcgtatcgc ctgacggttc gctttcccgg catcgttccg tccagcaagg
     7921 gcgcagcatg cgtgccattt acccttgctg gacgggttgt gttgggaaac gattaaccgg
     7981 aagctgatat gaagaacgaa aagtacacag gaggaaaaac tatgcccctg catagccgga
     8041 cttagcgccc cttagttcgc agcggtgaaa tggtttgggg gttaacactg cagcggtgat
     8101 acttgcaaat aatcatccga gtggtatctc tgagcccagt catgctggca aggtgatgag
     8161 ggtgcagatt aaaaaaggat tgggaatagt cgacatgcgt acattggctc actttacttc
     8221 ggaggtgagt ccacggtgtc cttcgctgaa tgggggttat tttgatcgca gggagcttcg
     8281 gcccccattt tgctgtgatc tatgttgaat tctccgtggc agcatgttcc ctacgctttg
     8341 gaataccgac tgtatgcgct gcttactttt attgtatttg attatactca atttatgtac
     8401 gattgacgta catcctcaaa acccttaccg ttgagtaata gcctgtcctt tttgtggcat
     8461 aatatgaccg cagctgcccg tcacccaaat gaagttctca cacaatggca tgatgctggt
     8521 ggtgtgttaa cgattgagct agcgcgccaa cttggtgtcc cagccaatgg aacacccaga
     8581 tcatcatcgg caaacgcagt attaccagcg actaagcact acggcttgct cattggttca
     8641 gcgattactc gcagttctgg atgcacttgt aggcactgta cgatttggag tttgtcgaaa
     8701 ctgaatcagg aatggctatc agatcgctcc ctactggcct aactgtttac tattgtaaga
     8761 ttaacaagca tacgaagcct gaattgggaa gatttatgac ggaagggctt acattgatga
     8821 gtgtatttgg agggaagtag cgcatgaatg atgcaccttc agacatcata tttcactatc
     8881 caccggagct gttcaatctc ctggtggatg ttgtgccgtt gctcaatcgc tctaagcagg
     8941 atgtgctggt tttcttccgg ggcgcaggag tacctgacaa cataacttct gacattgcag
     9001 ttcacttgag ggctgcacca aaggatgtca acaagtacca gatggttcgc acggtacttg
     9061 aacgcctcaa cgcgaagggg gaacacgctc tccgtgaacg gcgcgaggtg ctgcggcgcg
     9121 tggtggactt tgcgaacttt gattcgtgct ggcccgcaga ccaacttaag gccaaaggtc
     9181 ttgtcgccag tatccgcgaa gtcgtcaacc aaaaagacgc tttcacgcgc atgaacaatg
     9241 cccgcgaaga agaacggcaa acccgcctcg ctgagtcaca gcggatcgca gcagaaaaac
     9301 gtgatcgtag ttatagaatc gagaatgcca agcagggttt atataaatta tttggcacta
     9361 ctgcgactgc acaggaaaga ggaaaattgc tggagacggc tctcaacaat ctttttcaag
     9421 cctacggtgt tctcattcgt aaatcctttc atttggttgg tgaggctggt gaagggatcg
     9481 tcgagcagat tgatgggatc attgaactca gtggtgttct gtatttcgtt gaaatgaaat
     9541 ggtatcgcaa tccggtgggt aagcctgaga tttcagagca tcttgttcgc ctcatgtcgc
     9601 gtgccgaggt tcgaggtatc ttcatttctg ccagtgacta tacagaacca gccattctta
     9661 cggcacgtga atttctgcaa cacaaagttg tagtcctatc cacgcttcat gagatcgtcc
     9721 gtctgcttga gcagcaagac gacctttcag agttcttcac aaagaaagtc caggctgcgc
     9781 agatacacaa aaacccgtat ttctgcccac acgatagcca agcacaaggt gcgttatgac
     9841 tgcgagttgg atggacatca ataagccgcc gagcccagca accgctgtta cggcagctca
     9901 ggtggcgaac ggccccattt ttccaccgca gcaaagacta ctgacctact caccagacga
     9961 gtgggaggga ttcgtcgagg aatgggctta ttactgcctc acgacgaagt atgaacacgt
    10021 cctgcgtttc tctggtgctg gtgatatggg tattgatgtc gccgggttcg ttggtgatga
    10081 acgcctgctg ggggtttggg acaatttcca atgcaagcac tacggcaatg ccatcaggcc
    10141 tagtgatgtt tgggttgagt tcgggaagat catctggtac tcgtacaaag gtgaatatac
    10201 ggtccctcgt cgctactact ttgtttcgcc acgaggtgct ggtacgtcgc ttagccgcct
    10261 attttcgaat gacacgaagt tgcgtgagga attgttagct aactgggata agcatgtgaa
    10321 aaatgcaatc actagcacac aagaagtgtt actcgacgcg aagcttcgtg cctatgtaga
    10381 ctcattcgat tttaccatct tcgacgccaa gactgcgctt cagcttgttg acgatcacag
    10441 agccacaccg gttcacacag cgcgctttgg tggtggacta ccaacgcggc ctgcatctga
    10501 aaagccgccc caagaagttg ccgccaccga gagccgctat gtgacgcagt tgttcggcgc
    10561 atacagcgaa cacacaggaa caatagtgac tgacccttcg gccttgccct tgccgaaact
    10621 caaggatcat ttccgtcgcc agcgcgaggc gttctatgag gctgagtcac tgcgcgtctt
    10681 cgcacgtgat agtgtcccgc caggcacgtt cgaagctttg ctggatgaca ttcatgatgg
    10741 cgttattgat acacatgacg ggaaccatgc tgacggctac gaaaaggtct gcgctgtcac
    10801 caaggctgcc cgcgacatgc aaattacggc aaacgccctc atcatttgta ctaaccccaa
    10861 ggatagagac ggaatctgcc accaacttgt gaacgaagag cgccttcggt ggacacgatc
    10921 atgagccaag aacataagcc aattaccttc aatagcccac ttgaggcggg tatacgtgcg
    10981 gtctcgattc tgggtgctgc ctatccgcaa acctacgacc tccagcggct tgtggccttt
    11041 gactaccttc ttgttcacac gggcgatatt ggtggaccag acaatttgca cccaccgacg
    11101 ccaatgcgct ctgctgaatt gctcgtgcgc cgcaagttag ttgagcaatc actgcttctg
    11161 atgatgaccc gtgacctagt tgagcgcgaa gtcacatccg agggaatcaa gtacggcgcg
    11221 ggtgaaaatg ctgcaacgtt cctgtcatca gtatcttcca actatttgct gtccctgaag
    11281 gatcgcgctg tatggcttgt cgaaactatt ggtgatctga cggatgaaca gttcaaagcc
    11341 atgatgcgcc gtttcttcga taaatgggtc gaacagtttc agagcattga gcaaagctta
    11401 ggaggtgatg catgacgaca gtaactcccg gcttacgctt gcgctttctc ggtttttttg
    11461 ggccacaaaa gccacccgct acagtgacct tcggtactgg cctcaatgtc atttacggcg
    11521 catcaaacac tggaaaatct ttcattgtcg aagccatcga cttcatgctc ggtggaaagc
    11581 cgcctctgcg tgatatccct gagcgcgttg gctacgacct tgttctattg gggcttgaaa
    11641 cccttgatgg gaagtcattt acactctggc gcagcataga tggcggtggt tttcggctct
    11701 acgaagactt gcaccagacg ccaccaacaa acgaaattcc gtatacgcag cttgacgaaa
    11761 aacacagcga taagaacaat acgaaccttt catcattctt gctggatcta tgtagccttg
    11821 gtggaaagcg tgttcgcaaa aattcccgga acgaaaccct cagtttaagc tttcgcaaca
    11881 ttgcgcgttt gatgatcgtc gatgagacgg agatcacaca acaaagctca ccgcttattg
    11941 atggcaatcc caccgccaac acgccgaact tggccacatt caagttactt ttaaccggag
    12001 cagacgactc cgcattggtc gccaccagta ataagagtga gccggaagag ttatcgcgca
    12061 aggcacaatt gcgtcttctc gatcagcttc ttgaagacta tggtgaccgg ctcaaggagt
    12121 tgacaaagag tcctaaggaa ctcaaggagc agctagagaa gattaacacc tcacttcgtc
    12181 aacaggcggc ccaggtaaac accaccgaag atgagtttca ggaggctgcc gggaagcgac
    12241 gagaattacg caaaaaactg gaagaaagcc gagagcgacg tgcagaggta agtgcgatgc
    12301 ttgagcgatt caggctgctt gatagacact acttgtccga tattgaaagg ctacgtgcca
    12361 ttgaagaagg cgggacgctc tttagcgtac tgagtgccgg gcattgtcct ctttgcggag
    12421 cggcccccga tcatcatccc cccgatactg ggtgtaatgg agatactgat gccgtcgttc
    12481 aggctgcacg tgtggagatt gccaagatcg aagttttgcg cacggaactt gtagctaccg
    12541 tccaaagcct tgagcgcgaa ggcgccaact ttgatcgcag aatacccact gttgttcgag
    12601 aattagagtc gatttcggag tcagttgaag aattcctcgc tcccaagctc tcgacccttc
    12661 gcaagtccta ttcagacttt gccgacaagc gggccgaggt acgcgaagcg ctggcactct
    12721 atgccactgt tcaagacatg gagcgccgtc gggctgatct tgagaagggc actgaggacg
    12781 agaaggctgg ggtggttact aacgcagatc tctcaagcac tgtggcccat agttttgcta
    12841 agactgttga aggcatactg actggttggc acttcccaga ggttggggat gtgtacttcg
    12901 attccaagtc tcgagatctt gtaattgctg gaaagtcgcg tagtgctttt ggtaagggcc
    12961 ttcgcgccat tacgcatgca gctttcaccc tcgggctgct tgctttctgc cgtgagcgcc
    13021 acacaccaca cacgggattc gttgtactcg attctccatt gctggcatac agagagccag
    13081 atggaacaga atatgatttg accggtactg accttaaaga tcagttttac gcgtaccttg
    13141 aagcgctgcc tgaggacacc caagtcatcg ttgttgagaa caccgacccg cctgatgcaa
    13201 tcatgaagcg tgagcagtct cttatgtttg gcaagaatcc gcatcatggc cgttacggtt
    13261 tgttcccttt tatagccgac cctgcacaat aaatgtgtat acaaatggga agtcaccaat
    13321 gacttggtga cgatccagcg ttttttatcg aatagtatat gtacctcccc ttcgcgggtc
    13381 tggttgctcc agatttgcta ttcgcttatc cctgacaggc ttagccagtt ttccgtatcc
    13441 tgacacctcc ggcccgacgt cagattgccc acggggtggc tttaaaaaaa ctgggcgatg
    13501 ttgtgattcg ccgcgcccag tttcaatctc cgtagctgtc ctcgctcagg caaccacgtt
    13561 aatcccgcga gttgtctaaa atcggggcaa aattggctgc accggatgaa cccaacatcc
    13621 aggactttca ctgtcaaaaa aatcaacacg aacaggccct agatcgtcct gaataacctg
    13681 atacgcatgg ttgcaataga cctgattcca gcgataaacg gaaaccgcta cacgttggat
    13741 gccggttccg cgcatccgct tcagaatatg acggtcatgt tctccaagcc cccaaccaag
    13801 tatcgttaag gagggtcgct gcgacgtaag tacctcccgg tacacggtgg acagatagta
    13861 gctattctgg atagaagata ctttctgctg catcgttcct tcgctaacaa acagcggcac
    13921 cgcttgctcg ctgcgccact cttcaagaat tgcctcaagc aagccttctc cagcgttgtg
    13981 gatcttgaac tcctgctcca caacatttct gcacagggcc aagcttccat gcgggtagaa
    14041 aaccaaggtg ttagtacgct ctctaaaagt atcacgaaat ctccaccaag catcgtcgaa
    14101 gatgccgttc cacaagaaac aatccttgaa taaatgacca tcttggatgt cgaatccata
    14161 ggtcatcgtc cagtagatca acaagtcgta attcaacgat aaaacggtat cgaacccttt
    14221 gaggaactgg tacatattag gcaatttatc gctaacttgc tcatattcag ggtgtatatc
    14281 acgaacggcc tgaatcaaac aatttctgac attcaggtag gcttgatgtg tgcgattgtc
    14341 tggtatttga agtgatctgt ttacgttgga tgcctgccaa actagccgaa gaatcatctc
    14401 gaaatcggat gttctgaaaa attggaagag tcgattcata tcatgtgtaa gcagacctgc
    14461 cctgtgggcg taagccagta gagaaccgta gtcaaggacc ggtgaaacag caatgcttgc
    14521 accattaccc aacaatatcg tattccgatg atagttaggt gcaatttgag cccaaggcat
    14581 aatagcgtgt ggcatatctt attctctctt tttccttggc agtttattat gaaatagcac
    14641 tgataagcca ttttccacaa tttcttaagg ataaatcttt ttggtcgagt ttaaggcctt
    14701 tctgtacatg tcggcgcggt acgccaccga cgtaatggac ttgcctcata tccgaatgca
    14761 tcataccgcc acataatgtt tttggttctg tcccggcgtc gtaatacgct tctgttatcc
    14821 tttgcgcatc cagtccacgc caattttcgg attcagatcg atatcggctt catccagata
    14881 aaataccggc tggtccgtcc gcctctgggc tacagcctat tagatgggga gccacttttc
    14941 ctcataatgc agatgttgga ttttaagtgt tggcgaagct ctgggccaga tcattctgcc
    15001 cgtctcaagc atctatgtaa tgtagcggga tgcagtgaca cgttaaagag tcggttatcg
    15061 acctctatgt ccacaacgtg aagggctggc aataaaacca atatttttat gagagctggt
    15121 gctgtatgcg ctgatatact cgattacatt gaggtcttct acaacctgga acggcaccac
    15181 agccatctaa gccatttcat cccgaaggac ttcgaacagg tccagtgatg agggcaggaa
    15241 atatctacta tcgtggggtc aatccacgat ttaccagaag ctgatatgga aaatggaaag
    15301 catacaggag aaaaaatctg cctctgtata gctggacatg gagccccttg ctccgctgtg
    15361 gtgaaatagg ttgtggtagg atctagaggc gttagttcat atctaagatg ttagcctgct
    15421 tttaacgaca aacaggagta atatcataga gcgattggtt attagaaaca tacaccgcca
    15481 tcattaaaag ttatttttgg attaacatcg taattcgacc atatttaat
//
LOCUS       DAPOAV010000095        14805 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.095, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000095 DAPOAV010000000
VERSION     DAPOAV010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14805
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.095"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..579
                     /locus_tag="RN951_003606"
     CDS             <1..579
                     /locus_tag="RN951_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 domain-containing protein"
                     /protein_id="HDX2528551.1"
                     /translation="IGRPNNPFEPRRNRYAQKYLTLALMGGAAFFVLKGCSDSSDVDN
                     DGDGTFYATVQDCIDDGNNADICARGWNNAKTAFYADVPKNMTQQNCQSKYENCYYDN
                     VEQSWIPVVSGFLLSRVIRKDRDEPFVYNSGGSSFASRPVWRSTSGDYSWRSGSGKKE
                     SYSSGGFTTKKASTVSRGGYGRSSSARGHWGG"
     gene            582..1745
                     /locus_tag="RN951_003607"
     CDS             582..1745
                     /locus_tag="RN951_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HDX2528552.1"
                     /translation="MLRHNVPVRRDLDQIAADNGFDFHIIDNEIYWDESRAYRFTLRQ
                     IEEQIEKPTAELHQMCLEVVDRAVKDEEILTQLAIPPLYWDVIAESWRARDPSLYGRM
                     DFAWCGNAPVKLLEYNADTPTSLYESAYFQWLWLEDARRSGIIPRDADQYNAIQERLI
                     SRFSELYSREPFYFCCCQDTDEDRSTVLYLQDCAQQAGQESRFIYIEDLGLGVGGVLT
                     DLDDNVIQRAFKLYPLEWMMRDDNGPLLRKRREQWVEPLWKSILSNKGLMPLLWRFFP
                     GHPNLLASWFEGEKSQIAAGESYVRKPLYSREGGNVTIFDGQNNVVDHADGDYADEPM
                     IYQAFQPLPRFGDSYTLIGSWIVDDEACGMGIREDNTLITKDTSRFVPHYIAG"
     gene            1829..3454
                     /locus_tag="RN951_003608"
     CDS             1829..3454
                     /locus_tag="RN951_003608"
                     /EC_number="1.3.8.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418608.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isovaleryl-CoA dehydrogenase"
                     /protein_id="HDX2528553.1"
                     /translation="MHWQTHTVFNQPIPLNNSNLYLSDGALCEAVTREGAGWDSDFLA
                     SIGQQLGTAESLELGRLANVNPPELLRYDAQGRRLDDVRFHPAWHLLMQALCTNRVHN
                     LAWEEDARSGAFVARAARFMLHAQVEAGSLCPITMTFAATPLLLQMLPAPFQDWTTPL
                     LSDRYDSHLLPGGQKRGLLIGMGMTEKQGGSDVMSNTTRAERLEDGSYRLVGHKWFFS
                     VPQSDAHLVLAQTAGGLSCFFVPRFLPDGQRNAIRLERLKDKLGNRSNASCEVEFQDA
                     IGWLLGQEGEGIRLILKMGGMTRFDCALGSHAMMRRAFSLAIYHAHQRHVFGNPLIQQ
                     PLMRHVLSRMALQLEGQTALLFRLARAWDRRADAKEALWARLFTPAAKFVICKRGMPF
                     VAEAMEVLGGIGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLRVLNKQAGVYDLLS
                     EAFVEVKGQDRYFDRAVRRLQQQLRKPAEELGREITHQLFLLGCGAQMLKYASPPMAQ
                     AWCQVMLDTRGGVRLSEQIQNDLLLRATGGVCV"
     gene            complement(3571..3846)
                     /gene="yjfN"
                     /locus_tag="RN951_003609"
     CDS             complement(3571..3846)
                     /gene="yjfN"
                     /locus_tag="RN951_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418609.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease activator YjfN"
                     /protein_id="HDX2528554.1"
                     /translation="MKQLLASPSLQLVTYPASATAQSAEFASADCVTGLNEIGQISVS
                     NISGDPQDVERIVALKADEQGASWYRIITMYEDQQPDNWRVQAILYA"
     gene            complement(3995..4324)
                     /gene="bsmA"
                     /locus_tag="RN951_003610"
     CDS             complement(3995..4324)
                     /gene="bsmA"
                     /locus_tag="RN951_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418610.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm peroxide resistance protein BsmA"
                     /protein_id="HDX2528555.1"
                     /translation="MVSRKRNSVIYRFASLLLVLMLSACSALQGTPQPAPPVTDHPQE
                     IRRDQTQGLQRIGSVSTMVRGSPDDALAEIKAKAVAAKADYYVVVMVDETIVTGQWYS
                     QAILYRK"
     gene            4506..5255
                     /gene="yjfP"
                     /locus_tag="RN951_003611"
     CDS             4506..5255
                     /gene="yjfP"
                     /locus_tag="RN951_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HDX2528556.1"
                     /translation="MIEIESRELADIPVLHAYPVGQKDTPLPCAIFYHGFTSSSLVYS
                     YFAVALAQAGLRVIMPDAPDHGSRFSGDAARRLNQFWQILLQSMQEFTTLRAAIAEEK
                     WLLDDRLAVGGASMGAMTALGITARHPTVRCTASMMGSGYFTSLARSLFPPLIPETAA
                     QQNEFNNIVAPLAEWEATNHLEQLGDRPLLLWHGLDDDVVPADESLRLQQALSETGRD
                     KLLTCSWQPGVRHRITPEALDAAVTFFRQHL"
     gene            complement(5252..6007)
                     /gene="ulaR"
                     /locus_tag="RN951_003612"
     CDS             complement(5252..6007)
                     /gene="ulaR"
                     /locus_tag="RN951_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator UlaR"
                     /protein_id="HDX2528557.1"
                     /translation="MTEAQRHQILLEMLAQLGFVTVEKVVERLGISPATARRDINKLD
                     ESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCG
                     STAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSEN
                     SLYAGHWMFTSGKGLTAEGLYKTDMLTAMAEQKMLSVVGKLVVLVDSSKIGERAGMLF
                     SRADQIDMLITGKNANPEILQQLEAQGVSILRV"
     gene            complement(6115..7179)
                     /gene="ulaG"
                     /locus_tag="RN951_003613"
     CDS             complement(6115..7179)
                     /gene="ulaG"
                     /locus_tag="RN951_003613"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003856017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HDX2528558.1"
                     /translation="MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLG
                     CTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKQGHQMQRMAGVKKLQPNLRTTPFVL
                     DPFAIRQVDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKER
                     CIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDDRAVNYLFKTPG
                     GSLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADMLRMGEALNAKV
                     VIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHY
                     PRGFDDCFTIEPDLPFKSFL"
     gene            7534..8931
                     /gene="ulaA"
                     /locus_tag="RN951_003614"
     CDS             7534..8931
                     /gene="ulaA"
                     /locus_tag="RN951_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418614.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDX2528559.1"
                     /translation="MEILYNIFTVFFNQVMTNAPLLLGIVTCLGYILLRKSVSVIIKG
                     TIKTIIGFMLLQAGSGILTSTFKPVVAKMSEVYGINGAISDTYASMMATIDRMGDAYS
                     WVGYAVLLALALNICYVLLRRITGIRTIMLTGHIMFQQAGLIAVTLFIFGYSMWTTII
                     CTAILVSLYWGITSNMMYKPTQEVTDGCGFSIGHQQQFASWIAYKVAPFLGKKEESVE
                     DLKLPGWLNIFHDNIVSTAIVMTIFFGAILLSFGIDTVQAMAGKVNWTVYILQTGFSF
                     AVAIFIITQGVRMFVAELSEAFNGISQRLIPGAVLAIDCAAIYSFAPNAVVWGFMWGT
                     IGQLIAVGILVACGSSILIIPGFIPMFFSNATIGVFANHFGGWRAALKICLVMGMIEI
                     FGCVWAVKLTGMSAWMGMADWSILAPPMMQGFFSIGIAFMAVIIVIALAYMFFAGRAL
                     RAEEDAEKQLAEQSA"
     gene            8947..9252
                     /gene="ulaB"
                     /locus_tag="RN951_003615"
     CDS             8947..9252
                     /gene="ulaB"
                     /locus_tag="RN951_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIB"
                     /protein_id="HDX2528560.1"
                     /translation="MTVRILAVCGNGQGSSMIMKMKVDQFLTQSNIDHTVNSCAVGEY
                     KSELSGADIIIASTHIAGEITVTGNKYVVGVRNMLSPADFGPKLLEVIKEHFPQDVK"
     gene            9262..9726
                     /gene="ulaC"
                     /locus_tag="RN951_003616"
     CDS             9262..9726
                     /gene="ulaC"
                     /locus_tag="RN951_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIA"
                     /protein_id="HDX2528561.1"
                     /translation="MKLRDSLAENKSIRLQAEAETWQDAVKIGVDLLVAADVVEPRYY
                     QAILDAVEQHGPYFVLAPGLAMPHGRPEEGVKKTGFALVTLKKPLEFNHEDNDPVDIL
                     ITMAAVDANTHQEVGIMQIVNLFEDEENFDRLRACRTEQEVLDLIDRTNAAA"
     gene            9740..10390
                     /gene="ulaD"
                     /locus_tag="RN951_003617"
     CDS             9740..10390
                     /gene="ulaD"
                     /locus_tag="RN951_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HDX2528562.1"
                     /translation="MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGV
                     RAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVA
                     KEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLS
                     DMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG"
     gene            10400..11254
                     /gene="ulaE"
                     /locus_tag="RN951_003618"
     CDS             10400..11254
                     /gene="ulaE"
                     /locus_tag="RN951_003618"
                     /EC_number="5.1.3.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase UlaE"
                     /protein_id="HDX2528563.1"
                     /translation="MLSKQIPLGIYEKALPAGECWLERLQLAKTLGFDFVEMSVDETD
                     ERLSRLDWSREQRLALVNAIVETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKA
                     IQFAQDVGIRVIQLAGYDVYYQEANNETRRRFRDGLKESVEMASRAQVTLAMEIMDYP
                     LMNSISKALGYAHYLNNPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPG
                     VFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAEDPAAEVAKARDWVKARMA
                     KAGMVEAA"
     gene            11254..11940
                     /gene="ulaF"
                     /locus_tag="RN951_003619"
     CDS             11254..11940
                     /gene="ulaF"
                     /locus_tag="RN951_003619"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase UlaF"
                     /protein_id="HDX2528564.1"
                     /translation="MQKLKQQVFEANMELPRYGLVTFTWGNVSAIDRERGLVVIKPSG
                     VAYETMKAADMVVVDMSGKVVEGEYRPSSDTATHLELYRRYPSLGGIVHTHSTHATAW
                     AQAGLAIPALGTTHADYFFGDIPCTRGLSEEEVQGEYELNTGKVIIETLGNAEPLHTP
                     GIVVYQHGPFAWGKDAHDAVHNAVVMEEVAKMAWIARSINPQLNHIDSFLMNKHFMRK
                     HGPNAYYGQK"
     gene            complement(12069..12344)
                     /locus_tag="RN951_003620"
     CDS             complement(12069..12344)
                     /locus_tag="RN951_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDX2528565.1"
                     /translation="MFSRVLALLAVLLLSANTWAAIEINNHQARNMDDVQSLGVIYIN
                     HNFATESEARQALNEETDAQGATYYHVILMREPGSNGNMHASADIYR"
     gene            12672..13067
                     /gene="rpsF"
                     /locus_tag="RN951_003621"
     CDS             12672..13067
                     /gene="rpsF"
                     /locus_tag="RN951_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HDX2528566.1"
                     /translation="MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGR
                     RQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPM
                     VKAKDERRERRDDFANETADDADAGDSEE"
     gene            13074..13388
                     /gene="priB"
                     /locus_tag="RN951_003622"
     CDS             13074..13388
                     /gene="priB"
                     /locus_tag="RN951_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N"
                     /protein_id="HDX2528567.1"
                     /translation="MTNRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHR
                     QAWCQMPVIVSGHENQAITHSITVGSRITVQGFISCHKAKNGLSKMVLHAEQIELIDS
                     GD"
     gene            13393..13620
                     /gene="rpsR"
                     /locus_tag="RN951_003623"
     CDS             13393..13620
                     /gene="rpsR"
                     /locus_tag="RN951_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HDX2528568.1"
                     /translation="MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRI
                     TGTRAKYQRQLARAIKRARYLSLLPYTDRHQ"
     gene            13662..14111
                     /gene="rplI"
                     /locus_tag="RN951_003624"
     CDS             13662..14111
                     /gene="rplI"
                     /locus_tag="RN951_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HDX2528569.1"
                     /translation="MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNI
                     EFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADA
                     VTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE"
     gene            complement(14223..>14805)
                     /gene="dctP"
                     /locus_tag="RN951_003625"
     CDS             complement(14223..>14805)
                     /gene="dctP"
                     /locus_tag="RN951_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001422748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein DctP"
                     /protein_id="HDX2528570.1"
                     /translation="KSKGYFGLTFYDGGARSFYGNKPVLKPDDLKGMKVRVQPSPGAV
                     EMIKVMGGNPTPLDYGELYTALQQGVVDMAENSVMALTTMRHGEVAKSFSLDEHTMVP
                     DVVLMSNAAFDKLSQENQAVILKAAKESMSYMKDLWSEEEKQEFAKLDKMGVKVYQVD
                     KAPFIEKVQPMYANFAKDNPALAPMLADIQAAK"
BASE COUNT         3421 a         3651 c         3999 g         3734 t
ORIGIN      
        1 attggtagac cgaataatcc ttttgaaccg cgtcgcaatc gctacgcaca aaaatactta
       61 acgttggcgc taatgggcgg tgccgctttt ttcgtattga aaggttgtag cgatagtagc
      121 gatgtcgata acgacggcga cggaacgttt tacgcgacag tgcaggattg tattgatgac
      181 ggtaataatg ccgacatttg cgcgcgtggc tggaacaacg ccaaaacggc attttatgcc
      241 gatgttccga agaatatgac tcagcagaac tgtcagtcta agtacgaaaa ttgctactac
      301 gacaatgttg aacagagttg gatcccggtc gtttctggat ttttgttaag ccgggttatt
      361 cgtaaagatc gcgatgagcc gtttgtttat aacagcggcg gttcctcttt tgcttcgcgc
      421 ccagtctggc gcagcacttc tggtgattac tcttggcgct ccggttctgg caaaaaagag
      481 tcttactctt cgggcggctt taccaccaaa aaagcgtcta ccgtttctcg cggcggctat
      541 ggtcgttctt ccagcgcccg tgggcattgg ggaggctaat catgctgaga cacaacgttc
      601 ctgtgcgacg ggatctggac cagatcgccg ctgacaacgg tttcgacttt catatcatcg
      661 acaatgaaat ctattgggat gagagtcggg cttaccgttt tactctgcgc cagattgaag
      721 agcagatcga aaaaccgact gcggaactgc atcagatgtg ccttgaggtg gtggatcgcg
      781 cggtaaaaga tgaagagatc ctgacgcaac tggcgatccc gccgttgtac tgggatgtga
      841 tcgctgaaag ctggcgcgcc cgcgatcctt cgctgtatgg acggatggat tttgcctggt
      901 gtggcaatgc gccggtgaag ctgctggagt acaacgccga tacgccaact tcattgtacg
      961 agtcggctta tttccagtgg ctgtggctgg aggatgcccg gcgcagcggc attattccgc
     1021 gtgatgccga tcagtacaat gctattcagg aacgcctgat ttcacgcttt agcgagcttt
     1081 acagtcggga accgttttat ttttgctgct gtcaggacac cgatgaagac aggagtaccg
     1141 tgctgtactt gcaggactgc gcccagcagg cagggcagga gtcgcggttt atctacattg
     1201 aagatctcgg tttgggcgtc ggcggcgtac tgaccgatct tgatgataat gtcatccagc
     1261 gtgcatttaa gctgtatccg ctggagtgga tgatgcgtga cgataacggt ccgctgctgc
     1321 gcaagcgtcg cgagcaatgg gtggagccgt tatggaaaag tatcttgagt aataaagggc
     1381 taatgccgct gctttggcgc ttcttccctg gtcatcctaa ccttcttgca tcctggtttg
     1441 agggtgaaaa atcgcagatt gccgctggcg aaagctatgt gcgtaaaccg ctctactcgc
     1501 gcgaaggcgg aaatgtcacc attttcgacg gccagaataa cgtcgttgac cacgctgatg
     1561 gtgattacgc cgatgaaccg atgatctacc aggcgtttca acctctgccg cggtttggcg
     1621 atagctacac actcatcggt agctggattg tcgatgatga agcgtgcgga atggggatcc
     1681 gtgaagataa cacactgatc accaaagaca cctcacgttt cgttccgcat tacattgctg
     1741 gataagaatg ttttagcaat ctctttctgt catgaatcca tggcagtgac catactaatg
     1801 gtgactgcca ttgatggagg gagacacagt gcactggcaa actcacaccg tttttaatca
     1861 acctatacca ttaaataaca gcaacttata cctgtctgat ggcgcgctct gcgaagcggt
     1921 aacgcgtgaa ggtgctggct gggatagcga ttttctagcc agtattggtc agcagttagg
     1981 aacggctgaa tcccttgaac tggggcggct ggcgaatgtg aatccgcctg aattattgcg
     2041 ctacgatgcg caaggacgcc gtctggacga tgtgcgtttt caccccgcct ggcacctgct
     2101 gatgcaggcg ctatgtacca atcgggtgca caatcttgcc tgggaagaag acgctcgctc
     2161 cggcgcattt gtggcgcgcg cggcgcgttt tatgttacat gcgcaggttg aggcagggtc
     2221 gttatgtccg ataaccatga cctttgccgc cacgccattg ttgttacaga tgttacccgc
     2281 gccgtttcag gactggacca cgccgctatt gagcgatcgc tacgattctc acttattgcc
     2341 aggtgggcaa aaacgcggtt tgttgattgg catgggaatg acggaaaagc agggcggttc
     2401 cgatgttatg agcaacacca cccgtgcaga gcgtctggaa gatggctctt atcggctggt
     2461 ggggcataaa tggtttttct cggttccgca aagcgatgcg catctggtgc tggcgcagac
     2521 cgcgggtggt ctgtcctgct tttttgtgcc gcgctttttg cctgacgggc aacgcaacgc
     2581 gattcgcctc gagcggctga aagataagct gggtaatcgc tctaacgcca gttgcgaagt
     2641 ggagtttcag gatgccattg gttggttgtt ggggcaggaa ggggaaggaa ttcgtctgat
     2701 cctgaaaatg ggtgggatga cgcgttttga ttgcgccctg ggtagccatg ccatgatgcg
     2761 ccgtgcattt tcgctggcga tttatcatgc acatcaacgc catgtttttg gtaatccatt
     2821 gatccaacag ccccttatgc gtcatgtctt aagtcgcatg gcacttcagc ttgaagggca
     2881 aacggcgttg ctgtttcgtc ttgcgcgagc gtgggaccgg cgtgccgatg ccaaagaagc
     2941 cctgtgggcg cgtttattta cgcctgcggc aaaatttgtg atctgcaaaa gaggtatgcc
     3001 gtttgtggcc gaagcgatgg aggtgctggg cggcattggt tattgcgagg agagcgagct
     3061 gccgcggctt taccgggaga tgccggtaaa cagtatttgg gaaggttccg gcaatattat
     3121 gtgcctggat gtgttgcgcg ttctcaataa gcaagcgggc gtatacgact tattgtcgga
     3181 agcatttgtg gaagtgaaag ggcaggatcg ctattttgat cgcgcggttc gtcgtttaca
     3241 gcagcagctg cgtaagccag ctgaagaact ggggcgagag attactcatc agctattcct
     3301 gctgggctgc ggtgcgcaaa tgttgaaata tgcttctccg ccaatggcgc aggcgtggtg
     3361 tcaggtgatg ttagatacgc gcggcggcgt acggttgtca gagcagatcc agaatgattt
     3421 attgctgcgg gcgacggggg gagtgtgtgt gtaagcgtat acgactgatg cgacgctggt
     3481 ttcgattaac taaatgaaat atgtgaaaat tgtaggccgg acaaggcgct cgcgccgcat
     3541 ccggcattgt tcatttgctg tagatgacac tcatgcatac agtatcgcct gtacgcgcca
     3601 gttatcaggc tgctggtctt cgtacatggt aataatgcgg taccatgacg caccttgttc
     3661 atcggccttt aacgccacga tacgttccac gtcctgcgga tcccctgaaa tattgctaac
     3721 tgagatctga cctatttcat tcaggcccgt cacgcagtca gcactggcga attctgcaga
     3781 ctgtgccgtg gcgctcgcag gataagtcac taattgcagc gagggtgagg caagtaattg
     3841 tttcatcgtc agctccattt ttcgtttccc cacatgttgc agggcattcc atcgcggtaa
     3901 taaacgccca ggcttccagc cggtaattta ttgtgcacag gtaaacgcat agggacgcaa
     3961 agcaatgtaa agctgactat gtaagttgtc tgatttattt acggtacaaa atggcttgtg
     4021 aataccactg tcctgtcacg atggtttcgt ccaccatgac gacaacgtaa taatcagctt
     4081 ttgcagcgac agctttcgct ttgatttctg ctaatgcgtc atccggagaa ccccgaacca
     4141 tcgtgcttac gctacctatt cgctgtaacc cttgcgtctg gtcgcggcga atctcttgcg
     4201 gatggtccgt tactggcggt gctggctgtg gcgtaccttg cagtgcgcta caggcactta
     4261 acatcaacac caataataaa ctggcaaacc ggtaaataac gctattacgt ttcctgctaa
     4321 ccatagtgta gtgccttatt aatttaactt tgggggaatg ttcccgaatt gttacctggt
     4381 acgcgatttt cgaatgaaaa cgtgacgaaa gcgtaaccca catctcaaca ttatgaacta
     4441 ataccgccag cagaaacttg tgctaaggat ttcttcatgt cataccagac aaaaaggaga
     4501 gacagatgat tgaaatagaa tcacgcgagc tggcagatat tcccgttctt catgcttatc
     4561 ctgtcggaca aaaagatacc ccgttaccgt gcgcgatttt ttatcacggc tttacttcgt
     4621 ccagtctggt gtatagctat tttgccgttg cgctggcgca ggctggtttg cgggtgatca
     4681 tgccggatgc gcccgatcac ggtagtcgtt ttagtggcga cgcagcgcgg cggttaaatc
     4741 aattctggca aatcttgcta caaagtatgc aggaattcac tactttacgt gcggcaatag
     4801 ccgaagaaaa gtggctgctt gatgaccgtc tggcagtcgg tggtgcgtcg atgggcgcga
     4861 tgacggcact ggggattacc gctcgccacc ccacggtgag atgtaccgcc agcatgatgg
     4921 gatcgggcta ttttacatcg ctcgcccgtt cactgtttcc accgctgata cctgaaacgg
     4981 cagcacaaca gaatgaattc aataacattg tcgcgccgct ggcagagtgg gaagcgacaa
     5041 accacctgga acaacttggt gacagacctc tactgctgtg gcatggcctc gacgatgacg
     5101 ttgtgcctgc cgatgaatca ctacgtttgc agcaggcctt aagcgagacg ggacgggata
     5161 aactgctaac ctgttcatgg cagccaggcg tgcgtcaccg cattacgcct gaggcgttag
     5221 atgctgcagt gacatttttc cgccagcatc tttaaacacg cagaatgctg accccttgcg
     5281 cttccagttg ttgcaggatt tccgggttag catttttgcc ggtgatcagc atatcaattt
     5341 gatcggcacg gctaaaaagc attcccgcgc gttcgccaat cttactgcta tcaaccagta
     5401 ccaccagttt ccctaccacg ctcagcatct tctgctctgc cattgccgtc agcatatcgg
     5461 ttttatacaa cccttctgct gtcagtcctt tgccgctggt aaacatccag tgcccggcat
     5521 agagactgtt ttcgctgccc tgcgggctta aagtgatgga ctgacttttg ttgtactgtc
     5581 cgcccataat gatcacgctg tcatgttctt gatcgatcag gtaatttgcc agcggtagat
     5641 aattagtgat gatttgcact ggcttgccac acatttcccg cccaagcaga aacgcggtgg
     5701 agccgcagtt gatgactacg ctttcgcccg gattaaccag ctgcgaggcc gctttagcga
     5761 tacgtacttt ttcatcgtga ttctgcgcct gatgcagatt catcggcgtc cagcgcgggc
     5821 gctgttgggt aatagcttct gcgccattgc gcactttttt cagtttgccg ctttcgtcaa
     5881 gtttattgat atcgcgtcgc gcagtggcag gcgaaattcc cagacgctca acgactttct
     5941 caacggtcac aaagcccaat tgtgcgagca tttccaggag gatttgatgt ctttgtgctt
     6001 cagtcatgag ctattccgat aaaatttgat ttttttagat gatatttgaa atagccagga
     6061 aatactacgc cggatagcgc gaactactcc acgctatccg gtataaacga cagattacag
     6121 gaatgacttg aacggcagat ccggttcaat agtgaagcaa tcatcgaaac cacgcggata
     6181 gtggtactcg aagttgtctt tatccaacgg ccaggtaaat ttgccgccaa cctgccagat
     6241 aaacggcttg aagccatact tcaggcgatc ttttttcatc tcccacagca cgcggatctc
     6301 ttgcggatcg gcctggaagt ttgaccagat atcgtggtgg aacgggataa ccactttcgc
     6361 attcagggct tcacccatac gcagcatatc ggcgctggtc attttgtcgg tgataccgcg
     6421 cgggttttcg ccgtatgaac ctaaagccac gtcgatctga tgttcgttac cgtgcttcgc
     6481 ataatagtta gagtagtggg agtcgccgct gtgatacagg gagccgccag gcgttttgaa
     6541 cagatagttc accgcgcgat cgtccatgcc gtccggcagt acgccagccg ctttttgatc
     6601 ggcaggcagg gtgatcagtg cagtacggtc gaaagcgtca agcgcatgaa tttcaatgtc
     6661 tttcactttt acaacatcgc ccggtttgac cacgatgcaa cgctctttcg gtacgcccca
     6721 gccaatccac aaatccacac aggttttcgg tccaatgaac ggtacgtcat cagcacagtt
     6781 ctgcatcaca gcagcagcga cgttgacgtc gatatgatcg ttgtgatcgt gagtcgccag
     6841 taccgcgtcg acctggcgaa tcgcaaacgg atcaagaaca aacggggtgg tgcgcaggtt
     6901 tggctgcagt tttttcacgc cagccatgcg ctgcatttgg tgaccctgtt tcattaacgg
     6961 gttaccgtga ctttgtttgc cagtgccgca ccagaaatca acgcaaacgt tggtgccacc
     7021 ttccgatttt aaccagatcc cggtgcagcc aagccaccac atcgcaaatg tgccaggagc
     7081 gacctgttct tgttcaattt cttcattcaa ccagctaccc cactccggga aagtgctcag
     7141 gatccaggat tcacgggtga tacttttcac tttactcatc gccatttacc ttcatgatag
     7201 ttcaattcga atcaatatgt gattggtttt gattaatcct gacactattt tttcaggaag
     7261 gcaatgacca ttttttgact ttttgccagg gaagttgttg ttgattttga gtgtggaaag
     7321 atttaatgga atgtgtagtt aaattaacta aatgaattta aataaataat tgtttcgtta
     7381 tgtgaatccc actctatccg tgtggaatta tttgcgggtc gcgtcacatt taatcataaa
     7441 taatcttgtt gtgattactt ttgaaaatta gagtgagtgc acaacattcc gggtgtgcgg
     7501 aatacccggt tacctcttct tcaggagatc gttatggaga tcctctacaa catctttacc
     7561 gtgtttttta accaggtcat gaccaatgcc ccgttgttgc tgggtattgt gacctgtctg
     7621 ggctacatcc tactgcgcaa aagtgtcagc gttattatta aaggcacgat taaaactata
     7681 attggtttca tgttgttgca ggcagggtcc ggcatcctca ccagcacctt caaaccggtg
     7741 gtggcgaaaa tgtccgaagt ctacggcatt aacggcgcaa tttccgatac ttacgcgtcg
     7801 atgatggcaa ccatcgaccg catgggcgat gcctatagct gggtaggtta cgcggtgttg
     7861 ttagcgctgg cgctgaacat ctgttacgtg ctgctgcgtc gcattaccgg tattcgtacc
     7921 atcatgctga ctggtcatat catgttccag caggcggggc tgattgccgt tacgttgttt
     7981 attttcggct actccatgtg gacaaccatt atctgcacgg cgattctggt ttcgctctac
     8041 tggggcatta cctccaacat gatgtacaag ccgactcagg aagtgacgga cggctgcggt
     8101 ttctccatcg gtcaccagca gcagtttgca tcatggattg cctataaagt tgcgccgttc
     8161 ctcggcaaaa aagaggaaag cgttgaagac ctcaaactgc caggctggct gaatattttc
     8221 cacgacaaca tcgtctccac ggcgattgtc atgaccatct tctttggtgc cattctgctc
     8281 tccttcggta tcgacaccgt gcaggcgatg gcaggcaaag tgaactggac ggtgtacatc
     8341 ctgcaaactg gtttctcctt tgcggtggcg atcttcatca tcactcaggg cgtgcgcatg
     8401 tttgtggcgg aactctctga agcatttaac ggcatttccc agcgcctgat cccaggtgcg
     8461 gttctggcga ttgactgtgc ggctatttat agcttcgcgc cgaacgccgt ggtctggggc
     8521 tttatgtggg gcactatcgg tcagctgatt gcggttggca tcctggtcgc ctgcggttcc
     8581 tcgatcctga ttattcctgg ctttatcccg atgttcttct ccaacgccac catcggcgtg
     8641 ttcgctaacc acttcggcgg ctggcgtgcg gcgctgaaga tttgtctggt gatggggatg
     8701 atcgaaatct ttggttgcgt ctgggcggtg aaacttaccg gtatgagtgc ctggatgggt
     8761 atggcggact ggtcgattct ggcaccgccg atgatgcagg gcttcttctc catcggtatc
     8821 gcctttatgg ccgtcatcat tgtaattgca ctggcttata tgttcttcgc tggccgcgca
     8881 ctgcgcgcag aagaagatgc agaaaaacaa ctggcagaac agtctgctta ataaggagtt
     8941 ttgattatga ccgtacgtat tctggctgtg tgtggcaacg gacaaggcag ttccatgatc
     9001 atgaagatga aagtggacca gtttttaacc caatcaaaca ttgaccacac ggtaaacagc
     9061 tgcgcggttg gcgaatacaa aagcgagttg agcggcgcgg atatcatcat cgcttctacg
     9121 cacattgcgg gcgaaatcac cgtgaccggc aacaaatacg tggttggtgt gcgcaacatg
     9181 ctctctcctg ccgactttgg cccgaaactg ctggaagtga tcaaagagca tttcccgcag
     9241 gatgtgaagt aaggacgcgc catgaaatta cgtgattcgc tggcggagaa taaatccatc
     9301 cgcctgcagg ctgaagctga gacatggcag gacgcagtaa aaatcggcgt tgacctgctg
     9361 gtggcggcgg atgttgtcga gccgcgttac taccaggcga ttctggatgc ggttgaacag
     9421 cacggtccgt actttgtgct cgcaccaggc ctggcaatgc cgcacggtcg cccggaagag
     9481 ggcgttaaga aaaccggttt tgcgctggtg acgctgaaaa agcctctgga gttcaaccac
     9541 gaagataacg acccggtgga tatcctcatc accatggcgg cggtcgatgc caacacgcac
     9601 caggaagtgg gcatcatgca gatcgtcaac ctgtttgaag atgaagaaaa tttcgaccgt
     9661 ttacgtgcct gccgtaccga gcaggaagta ctggatctca ttgaccgcac caacgcggca
     9721 gcttaagaag gaattgaaga tgtcattacc gatgttacaa gtcgcgctgg acaaccagac
     9781 tatggatagc gcctacgaaa ccactcgcct gattgccgaa gaagtcgaca ttatcgaagt
     9841 gggtaccatt ctgtgcgtgg gcgaaggcgt gcgtgcggtt cgcgatctga aagcgcttta
     9901 cccgcacaaa atcgtactgg cagacgccaa aattgccgat gcgggcaaaa tcctctctcg
     9961 tatgtgcttc gaagccaacg ctgactgggt gacggtaatt tgctgtgcgg atatcaacac
    10021 cgccaaaggc gcgctggacg tagcaaaaga gtttaacggc gacgtgcaga tcgaactgac
    10081 cggctactgg acctgggaac aggcgcagca gtggcgtgac gcaggcattc agcaggtggt
    10141 ttatcaccgc agccgtgacg cgcaggccgc aggcgtagcg tggggcgaag cggacattac
    10201 cgcgatcaaa cgtctttccg atatgggctt caaagtcacc gtcaccggtg gcctggcgct
    10261 ggaagatctg ccgctgttca aaggtattcc gattcatgtg tttatcgctg gtcgcagcat
    10321 ccgtgatgcc gcttctccgg ttgaagctgc acgtcagttc aaacgttcca tcgccgaact
    10381 gtggggctaa ggagcggata tgttgtccaa acaaatcccg cttggcatct atgaaaaagc
    10441 gctccccgcc ggggagtgct ggctggaacg cctgcaactg gcaaaaacgt tgggcttcga
    10501 ttttgtcgag atgtcggtag atgaaacgga cgagcgcctg tcgcgcctcg actggagccg
    10561 cgagcagcgt ctggcgctgg tgaacgcgat tgttgaaacc ggcgtgcgcg tgccgtccat
    10621 gtgcctttct gctcatcgtc gtttcccgct gggcagtgaa gatgacgcgg tgcgggcgca
    10681 ggggctggag attatgcgta aagctatcca gttcgcccag gatgtcggta ttcgcgtgat
    10741 ccaactggcg ggctatgacg tttactatca ggaagccaat aacgaaacgc gtcgtcgttt
    10801 ccgtgacggc ctgaaagaga gcgttgagat ggcaagccgc gcgcaggtga cgctggcgat
    10861 ggagatcatg gattacccat tgatgaactc catcagcaag gcgctgggct acgcgcacta
    10921 tctcaacaac ccgtggttcc agctctaccc ggatatcggc aacctctcgg cgtgggacaa
    10981 cgacgtgcag atggagttgc aggccggaat cgggcatatc gtcgcggtac atgtgaaaga
    11041 caccaaaccg ggcgtcttca aaaacgtgcc gtttggcgaa ggcgtggtgg atttcgaacg
    11101 ttgtttcgaa acgctcaaac agagtggcta ttgcgggccg tacctgattg agatgtggag
    11161 cgaaacggcg gaagacccgg cggcagaagt ggcgaaagcg cgtgattggg tgaaagcgcg
    11221 catggcgaaa gcgggcatgg tggaggcggc ataatgcaaa agctaaaaca gcaggtattt
    11281 gaagccaaca tggagctgcc gcgctacggg ctggtgacct ttacctgggg caacgtcagc
    11341 gctatcgacc gcgaacgcgg gctggtggtg atcaagccca gcggcgttgc ctacgaaacc
    11401 atgaaagcgg ccgatatggt ggtggttgat atgagcggca aggtggtgga aggggagtat
    11461 cgcccatctt ccgacaccgc gacgcatctc gaactctacc gtcgttaccc gtcgcttggc
    11521 ggcattgtcc atacccactc cactcatgcc accgcatggg cgcaggcggg gctggcgatc
    11581 ccggcgttag gcaccacgca cgctgactac ttctttggtg atatcccgtg cacgcgcgga
    11641 ttaagcgaag aagaggtgca gggtgagtac gaactgaaca ctggcaaagt gattatcgaa
    11701 acgctgggca acgccgagcc gctgcatacg ccgggaattg tggtgtatca gcacggaccg
    11761 ttcgcctggg ggaaagatgc ccacgacgcg gtgcataacg cggtagtgat ggaagaagtg
    11821 gcgaaaatgg cgtggattgc gcgcagtatt aatccacaac tcaatcacat cgacagcttc
    11881 ctgatgaata aacacttcat gcgtaaacac ggtcctaacg cttattacgg gcagaagtag
    11941 aacacgcgct gcggaaattt ccttcctcgg gagataactg gtctaattcc gcagccgttt
    12001 ttcaaaaaaa gccccctgag aagggggcaa agcaaactat ggcaatgttt ctttggttat
    12061 acctggtgct agcgataaat atccgcgctg gcgtgcatat tgccgttact ccccggttcc
    12121 cgcatcagaa tcacgtggta gtacgttgcg ccctgcgcat ctgtctcttc atttaatgcc
    12181 tgacgcgctt cgctttcagt ggcgaaatta tgattgatat aaatcacgcc taagctttgc
    12241 acatcgtcca tatttctggc ctggtggtta ttaatttcaa tggctgccca tgtatttgca
    12301 cttagcaaaa gcacagccag aagggctaaa acacggctga acatagatac ctcctcgacg
    12361 gctgtttttg tgtgctctcc tcatgtggtg atggtctgat ttaattttaa tcacggatga
    12421 aaaagttgat ggcgaccatt tctgatgcag ttgttcaaaa aaacagcatg atgaagtgtg
    12481 atgaacttca aatcagcggc ttagtggtta tttgcgaaag gggagattta tttctgctct
    12541 gcccttgagt ttagcaaggt atgtcagtac tataacgcgt catttttcag ccgaccttta
    12601 acacgttcct tgcctccccg ggattcggct gacccagaca ggaggctgaa taatccgtaa
    12661 ggagcaattc gatgcgtcat tacgaaatcg tttttatggt ccatcctgac cagagcgaac
    12721 aggttccggg catgatcgag cgctacactg ctgccatcac tggtgcagaa ggcaagatcc
    12781 accgtctgga agactggggc cgccgtcagc tggcttaccc gatcaacaaa ctgcacaaag
    12841 cacactacgt tctgatgaac gttgaagctc cgcaggaagt gatcgatgag ctggaaacta
    12901 ccttccgctt caacgatgcc gttattcgca gcatggttat gcgtaccaag cacgctgtta
    12961 ccgaagcatc tccgatggtt aaagcgaaag acgagcgccg cgagcgtcgc gatgatttcg
    13021 caaacgaaac cgcagatgat gcagatgctg gggattctga agagtaattt ctgatgacca
    13081 accgtctggt gttgtccggc accgtgtgca ggactcccct tcgaaaggtc agtccatcag
    13141 gaattcctca ctgccagttc gtgcttgagc atcgttctgt gcaggaggaa gccggttttc
    13201 accggcaggc atggtgtcaa atgcccgtta ttgttagcgg acacgaaaac caggccatta
    13261 ctcacagtat aacggtcggc agtcgcataa ccgttcaggg gttcatttca tgccacaagg
    13321 caaagaacgg actgagcaaa atggttttgc atgccgagca gattgaattg atagattctg
    13381 gagactagcc atatggcacg ttatttccgt cgtcgcaagt tctgccgttt caccgcggaa
    13441 ggcgttcaag agatcgacta taaagatatc gctacgctga aaaactacat caccgaaagc
    13501 ggtaagattg tcccaagccg tatcaccggt acccgtgcaa aataccagcg tcagctggct
    13561 cgcgctatca aacgcgctcg ctacctgtcc ctgctgccgt acactgatcg ccatcagtaa
    13621 tcggtcacgg tccattaata cgactttgag aggataaggt aatgcaagtt attctgcttg
    13681 ataaagtagc aaacctgggt agcctgggtg atcaggtaaa cgttaaagcg ggctatgctc
    13741 gtaacttcct ggtaccgcag ggtaaagctg ttccagctac caagaaaaac attgaattct
    13801 tcgaagcacg tcgcgctgaa ctggaagcta aactggctga agttctggca gctgctaatg
    13861 ctcgcgctga gaaaatcaat gcactggaaa ctgttaccat cgcgtctaaa gctggcgacg
    13921 aaggtaaact gttcggttcc atcggtactc gcgacatcgc tgacgctgta actgcagctg
    13981 gcgttgaagt ggctaagagc gaagttcgtc tgccgaacgg cgttctgcgt accactggcg
    14041 aacacgaagt gagcttccag gttcacagcg aagtattcgc gaaagtgatc gtaaacgtag
    14101 tagctgaata attcgttatt caacgagacg taaaaacgcc gaccattggt cggcgttttg
    14161 cttttgtagc gagcacttgc agatatcgat aagggccaca ataagcagcc ctacgaagat
    14221 aattacttag ctgcctgaat atcagccagc attggggcaa gggctgggtt gtccttagcg
    14281 aagtttgcgt acattggctg tactttctcg ataaacggag ctttatctac ctggtagact
    14341 ttcacgccca ttttatccag ttttgcaaat tcttgtttct cttcctcgct ccacaagtct
    14401 ttcatgtagc tcattgattc tttagctgct tttaatataa ctgcctgatt ttcctggcta
    14461 agtttatcaa acgcagcatt gctcatcaga accacatcgg gaaccatagt gtgttcgtca
    14521 aggctgaagg attttgccac ttcaccgtga cgcatggtag tcagcgccat cacgctgttt
    14581 tctgccatat cgaccacacc ctgctgtaag gctgtataca actcgccgta atccagtggc
    14641 gtcgggttac cgcccatgac tttgatcatt tcaactgcgc cagggcttgg ctggacacgg
    14701 actttcatgc ctttcagatc gtctggtttc agtactggtt tattgccata gaaactgcgg
    14761 gcgcctccat cataaaaagt cagcccgaaa taacctttgc ttttc
//
LOCUS       DAPOAV010000096        14639 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.096, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000096 DAPOAV010000000
VERSION     DAPOAV010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14639
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.096"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            70..636
                     /locus_tag="RN951_003626"
     CDS             70..636
                     /locus_tag="RN951_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDX2528571.1"
                     /translation="MFKGQKTLAALAVSLLFTAPVYAADEGSGEIHFKGEVIEAPCEI
                     HPEDIDKNIDLGQVTTTHINREHHSNKVAVDIRLINCDLPASDNGSGMPVSKVGVTFD
                     STAKTTGATPLLSNTSAGEATGVGVRLMDKNDGNIVLGSAAPDLDLDASSSEQTLNFF
                     AWMEQIDNAVDVTAGEVTANATYVLDYK"
     gene            687..3143
                     /locus_tag="RN951_003627"
     CDS             687..3143
                     /locus_tag="RN951_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706516.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDX2528572.1"
                     /translation="MDTVNIYRLSFVSCLVMAMPCAMAVEFNLNVLDKSMRDRIDISL
                     LKEKGVIAPGEYFVSVAVNNNKISNGQKINWQKKGDKTIPCINDSLVDKFGLKPDIRQ
                     SLPQIDRCIDFSSRPEMLFNFDQANQQLNISIPQAWLAWHSENWAPPSTWKEGVAGVL
                     MDYNLFASSYRPQDGSSSTNLNAYGTAGINAGAWRLRSDYQLNKTDSEDNHDQSGGIS
                     RTYLFRPLPQLGSKLTLGETDFSSNIFDGFSYTGAALASDDRMLPWELRGYAPQISGI
                     AQTNATVTISQSGRVIYQKKVPPGPFIIDDLNQSVQGTLDVKVTEEDGRVNNFQVSAA
                     STPFLTRQGQVRYKLAAGQPRPSMSHQTENETFFSNEVSWGMLSNTSLYGGLLISDDD
                     YHSAAMGIGQNMLWLGALSFDVTWASSHFDTQQDERGLSYRFNYSKQVDATNSTISLA
                     AYRFSDRHFHSYANYLDHKYNDSDAQDEKQTISLSVGQPITPLNLNLYANLLHQTWWN
                     ADASTTANITAGFNVDIGDWRDISISTSFNTTHYEDKDRDNQIYLSISLPFGNGGRVG
                     YDMQNSSHSTIHRMSWNDTLDERNSWGMSAGLQSDRPDNGAQVSGNYQHLSSAGEWDI
                     SGTYAASDYSSVSSSWSGSFTATQYGAAFHRRSSTNEPRLMVSTDGVADIPVQGNLDY
                     TNHFGIAVVPLISSYQPSTVAVNMNDLPDGVTVAENVIKETWIEGAIGYKSLASRSGK
                     DVNVIIRNASGQFPPLGADIRQDDSGISVGMVGEEGHAWLSGVAENQLFTVVWGEQSC
                     IIHLPERLEDTTKRLILPCH"
     gene            3158..3886
                     /locus_tag="RN951_003628"
     CDS             3158..3886
                     /locus_tag="RN951_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDX2528573.1"
                     /translation="MTFIKGLPLMLLTISLGCNAAVQPDRTRIVFNANDKATSLRIEN
                     QSDKLPYLAYSWIENEKGEKSDALLVALPPIQRLEPKATSQVRVVKQASTTQLPGDRE
                     TLFFYNMREIPPAPDKSSDHAILQVAIQSRIKLFWRPAALRKKAGEKVELQLQVSQQG
                     NQLTLKNPTAYYLTIAYLGRNEKGVLPGFKTVMVAPFSTVNTNTGSYSGSQFYLGYMD
                     DYGALRMTTLNCSGQCRLQAVEAK"
     gene            3883..4944
                     /locus_tag="RN951_003629"
     CDS             3883..4944
                     /locus_tag="RN951_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415244.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX2528574.1"
                     /translation="MSAGKGLLLVICLLFLPLKSAMALNCYFGTSGGAVEKSEAIQPF
                     AVPGNAKPGDKIWESDDIKIPVYCDNNTNGNFESEHVYAWVNPYPGVQDRYYQLGVTY
                     NGVDYDASLGKSRIDTNQCIDSKNIDIYTPEQIIAMGWQNKICSGDPANIHMSRTFLA
                     RMRLYVKIREMPPHDYQSTLSDYIVVQFDGAGSVNEDPTAQNLKYHITGLENIRVLDC
                     SVNFSISPETQVIDFGKFNLLDIRRHTMSKTFSIKTTKSQNDQCTDGFKVSSSFYTEE
                     TLVEEDKALLIGNGLKLRLLDENASPYTFNKYAEYADFTSDMLVYEKTYTAELSSIPG
                     TPIEAGPFDTVVLFKINYN"
     gene            5096..6142
                     /locus_tag="RN951_003630"
     CDS             5096..6142
                     /locus_tag="RN951_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415243.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDX2528575.1"
                     /translation="MPVLQWGMLCVLSLLLSIGFLAVHLPAALLLGPMIAGIIFSMRG
                     ITLQLPRSAFLAAQAILGCMIAQNLTGSILTTLAVNWPIVLAILLVTLLSSAIVGWLL
                     VRYSSLPGNTGAWGSSPGGAAAMVAMAQDYGADIRLVAFMQYLRVLFVAGAAVLVTRM
                     MLGDNAEAVNQHIVWFPPVSINLLLTILLAVVAGTVGCLLRLPSGTMLIPMLAGAVLQ
                     SGQLITIELPEWLLAMAYMAIGWRIGLGFDKQILLRALRPLPQILLSIFALLAICAGM
                     AWGLTRFMHIDFMTAYLATSPGGLDTVAVIAAGSNADMALIMAMQTLRLFSILLTGPA
                     IARFISTYAPKRSA"
     gene            complement(6139..6930)
                     /gene="nei"
                     /locus_tag="RN951_003631"
     CDS             complement(6139..6930)
                     /gene="nei"
                     /locus_tag="RN951_003631"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease VIII"
                     /protein_id="HDX2528576.1"
                     /translation="MPEGPEIRRAADNLEAAIKGKPLTDVWFAFPQLKPYQSQLIGQH
                     VTHVETRGKALLTHFSNDLTLYSHNQLYGVWRVVDTGEEPQTTRVLRVKLQTADKTIL
                     LYSASDIEMLTPEQLTTHPFLQRVGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLD
                     QAFLAGLGNYLRVEILWQVGLTGNHKAKDLNAAQLDALAHALLEIPRFSYATRGQVDE
                     NKHHGALFRFKVFHRDGEPCERCGSIIEKTTLSSRPFYWCPGCQH"
     gene            complement(6966..7700)
                     /gene="pxpA"
                     /locus_tag="RN951_003632"
     CDS             complement(6966..7700)
                     /gene="pxpA"
                     /locus_tag="RN951_003632"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpA"
                     /protein_id="HDX2528577.1"
                     /translation="MKIDLNADLGEGCASDAELLTLVSSANIACGFHAGDAQIMQACV
                     REAIKNGVAIGAHPSFPDRENFGRSAMQLPPETVYAQTLYQIGALATIARAQGGVMRH
                     VKPHGMLYNQAAKEAQLADAIARAVYACDPALILVGLAGSELIRAGKQYGLTTREEVF
                     ADRGYQADGSLVPRSQSGALIENEEQALAQTLEMVQHGRVKSITGEWATVAAQTVCLH
                     GDGEHALAFARRLRSAFAEKGIVVAA"
     gene            complement(7690..8622)
                     /gene="pxpC"
                     /locus_tag="RN951_003633"
     CDS             complement(7690..8622)
                     /gene="pxpC"
                     /locus_tag="RN951_003633"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpC"
                     /protein_id="HDX2528578.1"
                     /translation="MLKIIRAGMYTTVQDGGRHGFRQSGISHCGALDMPALRIANLLV
                     GNDANAPALEITLGQLTVEFETDGWFALTGAGCEARLDDNAVWTGWRLPMKAGQRLTL
                     KRPQHGMRSYLAVAGGIDVPPVMGSCSTDLKVGIGGLEGRLLKDGDRLPIGKSKRDSM
                     EAQGVKQLLWGNRIRALPGPEYHEFDRASQDAFWRSPWQLSSQSNRMGYRLQGQILKR
                     TTDRELLSHGLLPGVVQVPHNGQPIVLMNDAQTTGGYPRIACIIEADMYHLAQIPLGQ
                     PIHFVQCSLEEALKARQDQQRYFEQLAWRLHNEN"
     gene            complement(8616..9272)
                     /gene="pxpB"
                     /locus_tag="RN951_003634"
     CDS             complement(8616..9272)
                     /gene="pxpB"
                     /locus_tag="RN951_003634"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HDX2528579.1"
                     /translation="MQRARCYLIGETAVVLELEPPVTLASQKRIWRLAQRLVDMPNVV
                     EAIPGMNNITVILRNPESLALDAIERLQRWWEESEALEPESRFIEIPVVYGGAGGPDL
                     AVVAAHCGLSEKQVVELHSSVEYVVWFLGFQPGFPYLGSLPEQLHTPRRAEPRLLVPA
                     GSVGIGGPQTGVYPLATPGGWQLIGHTSLSLFDPARDEPILLRPGDSVRFVPQKEGVC
                     "
     gene            complement(9295..10038)
                     /gene="ybgI"
                     /locus_tag="RN951_003635"
     CDS             complement(9295..10038)
                     /gene="ybgI"
                     /locus_tag="RN951_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radiation resistance protein YbgI"
                     /protein_id="HDX2528580.1"
                     /translation="MKNTELEQLINEKLNSAAISDYAPNGLQVEGKETVQKIVTGVTA
                     SQALLDEAVRLGADAVIVHHGYFWKGESPVIRGMKRNRLKTLLANDINLYGWHLPLDA
                     HPELGNNAQLAALLGITVMGEIEPLVPWGELTMPVPGLELASWIEARLGRKPLWCGDT
                     GPEVVQRVAWCTGGGQSFIDSAARFGVDAFITGEVSEQTIHSAREQGLHFYAAGHHAT
                     ERGGIRALSEWLNENTDLDVTFIDIPNPA"
     gene            10309..11790
                     /gene="dtpD"
                     /locus_tag="RN951_003636"
     CDS             10309..11790
                     /gene="dtpD"
                     /locus_tag="RN951_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide permease DtpD"
                     /protein_id="HDX2528581.1"
                     /translation="MNKHASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYND
                     THAYELFSAYCSLVYVTPILGGFLADKVLGNRMAVMLGALLMAIGHVVLGASEIHPSF
                     LYLSLAIIVCGYGLFKSNVSCLLGELYEPTDPRRDGGFSLMYAAGNVGSIIAPIACGY
                     AQEEYSWAMGFGLAAVGMIAGLVIFLCGNRHFTHTRGVNKKVLRATNFLLPNWGWLLV
                     LLVATPALITILFWKEWSVYALIVATIIGLGVLAKIYRKAENQKQRKELGLIVTLTFF
                     SMLFWAFAQQGGSSISLYIDRFVNRDMFGYTVPTAMFQSINAFAVMLCGVFLAWVVKE
                     SVAGNRTVRIWGKFALGLGLMSAGFCILTLSARWSAMYGHSSLPLMVLGLAVMGFAEL
                     FIDPVAMSQITRIEIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQASFDASGAINY
                     SINAYIEVFDQITWGALACVGLVLMIWLYQALKFRNRALALES"
     gene            complement(11940..13358)
                     /gene="phrB"
                     /locus_tag="RN951_003637"
     CDS             complement(11940..13358)
                     /gene="phrB"
                     /locus_tag="RN951_003637"
                     /EC_number="4.1.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HDX2528582.1"
                     /translation="MTTHLVWFRQDLRLHDNLALAAACRNSSARVLALYIATPRQWAT
                     HNMSPRQAELINAQLNGLQIALAEKGIPLLFREVDDFVASVEIVKQVCAENSVTHLFY
                     NYQYEVNERARDVEVERALRNVVCEGFDDSVILPPGAVMTGNHEMYKVFTPFKNAWLK
                     RLREGMPECVAAPKVRSSGSIEPSPSITLNYPRQSFDTAHFPVEEKAAIAQLRQFCQN
                     GAGEYEQQRDFPAVEGTSRLSASLATGGLSPRQCLHRLLAEQPQALDGGAGSVWLNEL
                     IWREFYRHLITYHPSLCKHRPFIAWTDRVQWQSNPAHLQAWQEGKTGYPIVDAAMRQL
                     NSTGWMHNRLRMITASFLVKDLLIDWREGERYFMSQLIDGDLAANNGGWQWAASTGTD
                     AAPYFRIFNPTTQGEKFDHEGEFIRQWLPELRDVPGKVVHEPWKWAQKAGVTLDYPQP
                     IVEHKEARVQTLAAYEAARKGK"
     gene            complement(13355..13864)
                     /locus_tag="RN951_003638"
     CDS             complement(13355..13864)
                     /locus_tag="RN951_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HDX2528583.1"
                     /translation="MNLQRFDDSTLIRIFALHELHRLKEHGLTRGALLDYHSRYKLVF
                     LAHSQPEYRKLGPFVADIHQWQNLDDYYNQYRQRVVVLLSHPANPRDHTNVLMHVQGY
                     FRPHIDSTERQQLAALIDSYRRGEQPLLAPLMRIKHYMALYPDAWLSGQRYFELWPRV
                     INLRHSGVL"
     gene            complement(14015..14639)
                     /locus_tag="RN951_003639"
                     /pseudo
     CDS             complement(14015..14639)
                     /locus_tag="RN951_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421020.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
BASE COUNT         3523 a         3889 c         3574 g         3653 t
ORIGIN      
        1 ctagcaataa tcaaatacga tattctggcg tagctatacc cctattctat atccttaaag
       61 gactctgtta tgtttaaagg acaaaaaaca ttggccgcac tggccgtatc tctgctgttc
      121 actgcacctg tttatgctgc tgatgaaggt tctggcgaaa ttcactttaa gggggaggtt
      181 attgaagcac cttgtgaaat tcatccagaa gatattgata aaaacataga tcttggacaa
      241 gtcacgacaa cccatataaa ccgggagcat catagcaata aagtggccgt cgacattcgc
      301 ttgatcaact gtgatctgcc tgcttctgac aacggtagcg gaatgccggt atccaaagtt
      361 ggcgtaacct tcgatagcac ggctaagaca actggtgcta cgcctttgtt gagcaacacc
      421 agtgcaggcg aagcaactgg ggtcggtgta cgactgatgg acaaaaatga cggtaacatc
      481 gtattaggtt cagccgcgcc agatcttgac ctggatgcaa gctcatcaga acagacgctg
      541 aactttttcg cctggatgga acaaattgat aatgcagtcg atgtcacggc aggtgaagta
      601 accgctaacg caacctacgt gctggattat aaataagtat tattttggcg gcatcatcgc
      661 cgcctttcat aaaatattta tcaggtatgg acaccgtgaa tatttatcga ctctcttttg
      721 tatcctgcct ggtcatggcg atgccttgcg caatggcggt cgaattcaat ctgaatgttc
      781 tcgataaatc aatgcgcgac cgcattgata tttcattatt aaaggaaaaa ggagtcattg
      841 ctcccggtga atattttgtt agcgttgcgg tgaataacaa caaaatcagt aatgggcaaa
      901 aaattaactg gcaaaaaaag ggtgacaaaa ccattccatg catcaatgat tcactggtcg
      961 ataaatttgg tttaaaacca gatatccgtc agtccttgcc acagatagat cggtgtattg
     1021 atttcagttc ccgacctgaa atgctcttca atttcgatca agccaatcag caactgaata
     1081 ttagtattcc gcaagcctgg ctggcgtggc actcagaaaa ctgggctccc ccctctacat
     1141 ggaaagaagg tgttgccggt gtcctgatgg attacaactt gtttgccagc agctaccgcc
     1201 cacaggacgg cagcagcagc actaacctga atgcctacgg taccgccgga attaacgccg
     1261 gggcatggcg cttacgcagt gattaccagc ttaataagac cgatagcgaa gataaccatg
     1321 accagtcagg cggaatatcg cgcacctatc tttttcgtcc attaccgcaa ttaggctcta
     1381 agttaaccct cggcgaaacc gatttcagtt ccaatatttt cgatggtttt tcttataccg
     1441 gcgcggcact ggcgagtgac gatcgaatgt taccgtggga gctgcgtggc tacgccccac
     1501 aaattagcgg tattgcacag accaatgcca cggtgacgat cagtcaatca ggccgcgtca
     1561 tttaccagaa aaaagtcccg ccaggcccgt ttattattga tgacctcaat cagtctgttc
     1621 agggcacgct ggatgtcaaa gtgacggaag aagatggtcg ggtgaacaat ttccaggttt
     1681 cggcagcatc gacgcccttc ctgactcgcc agggacaggt tcgctataaa ttggccgcgg
     1741 gtcagccacg gccttccatg tcacatcaaa ctgaaaatga aacctttttt agcaatgaag
     1801 tttcctgggg gatgctctca aacacctcgc tgtacggcgg cctgctgatt tctgatgatg
     1861 actaccattc tgccgcaatg ggtatcgggc aaaatatgct gtggcttggc gcactgtcct
     1921 ttgatgtcac ctgggccagt agccattttg atactcagca ggacgagcgg ggcttaagct
     1981 accgttttaa ttacagcaaa caagtggatg ccaccaacag cacgatttcg ctcgccgctt
     2041 atcgcttctc agatcgtcat tttcacagct acgccaacta tctggatcac aaatacaacg
     2101 acagcgatgc gcaggacgaa aaacagacga tcagcttatc cgtgggccaa ccgattaccc
     2161 cactaaacct caatctttac gccaacctgc tacatcaaac ctggtggaat gcagacgcct
     2221 ccacgaccgc caacatcaca gcaggtttta atgttgatat tggtgactgg agagatatct
     2281 cgatttcgac gtcattcaat acgacccact acgaagataa agatcgcgac aaccagattt
     2341 atctgtcgat ttcgctcccc ttcggtaacg gtggtcgggt tggctatgac atgcaaaaca
     2401 gtagccacag caccatacac cgcatgtcgt ggaacgatac gctggatgaa cgtaatagct
     2461 ggggcatgtc tgccggactg caatccgatc gtccggacaa tggagcccag gtgagcggta
     2521 actatcagca cctgagttca gcgggtgagt gggatatttc tggtacctat gccgccagtg
     2581 attacagttc cgtcagcagc agctggagcg gttctttcac cgcaacccaa tatggtgcag
     2641 catttcatcg ccgcagctcc accaatgaac cacgcctgat ggtcagcacc gatggcgtgg
     2701 cagatattcc ggttcagggc aatctcgact acaccaacca ttttggcatt gcggtggtgc
     2761 cgttgatttc cagttaccag ccttccaccg tggcggtgaa catgaatgac ttacccgacg
     2821 gcgtaacagt tgcagaaaac gtcatcaagg aaacatggat tgaaggcgcg ataggttaca
     2881 aatcactggc ttcccgttcc ggtaaagacg ttaacgtcat catacgcaac gccagcggtc
     2941 agttccctcc cctcggtgcg gatatccgcc aggatgacag cggcattagc gtgggtatgg
     3001 ttggcgagga aggacatgcc tggttaagcg gtgtcgctga aaatcaactg tttaccgtgg
     3061 tctggggtga gcaaagctgc attattcatc tgccagaacg tctggaagac acgaccaaac
     3121 gcctgatttt accttgtcat taattaagga aaagagaatg acatttatta aaggattacc
     3181 cttaatgttg ttaaccatca gcttgggttg caatgctgcg gtgcaacccg atcgcacacg
     3241 cattgtgttt aacgccaatg acaaagccac cagcctgcgt atcgaaaacc aaagtgacaa
     3301 actgccttat cttgcttatt cctggataga aaatgaaaaa ggggagaaaa gcgatgctct
     3361 tctggtcgct ttgcccccta ttcaacgtct ggaaccgaaa gcgacatcgc aggtgcgggt
     3421 tgtgaaacaa gcctcaacca cacaattacc tggcgatcgc gaaacgctat ttttctacaa
     3481 tatgcgcgaa attcctcccg ctccggataa aagcagcgac catgcgatac ttcaggtcgc
     3541 tattcaaagt cgtattaaat tgttctggcg accggctgca ttacgcaaga aagcaggaga
     3601 aaaggtcgaa ctgcagttac aggtcagcca gcagggcaac caactgacac tgaaaaatcc
     3661 taccgcgtat tatctgacca ttgcctatct ggggagaaat gaaaaaggcg ttctcccagg
     3721 cttcaaaacc gtgatggttg caccttttag tacggtcaac acaaacaccg gaagttatag
     3781 cggcagccag ttttatctcg gttacatgga tgattacggc gcattacgca tgacgacgct
     3841 caactgcagc ggacaatgcc gtttacaagc agtggaggcg aaatgagtgc tggcaaggga
     3901 ttgttgctcg tcatctgcct gttatttctg ccgttgaagt ctgcaatggc gctgaactgc
     3961 tattttggta catctggtgg cgcagtagaa aaatcagaag cgattcaacc gtttgctgta
     4021 ccaggcaatg ccaaacccgg tgataagatc tgggaatctg acgatattaa aattcccgtc
     4081 tattgtgaca acaataccaa cggcaacttt gaaagcgagc atgtctacgc ctgggtaaac
     4141 ccctatccgg gggtgcagga tcgttattat caactcggcg tgacatacaa cggtgtcgat
     4201 tacgatgcca gtctgggaaa aagtcgcatc gacactaacc agtgtatcga cagtaagaac
     4261 attgatattt atacccctga gcagatcatc gcgatgggat ggcagaacaa aatttgctcg
     4321 ggcgatcccg ctaatattca tatgtcgcgt acctttctcg ctcgcatgcg gttatacgtc
     4381 aaaatacgag aaatgccgcc gcatgattat caaagtacgc ttagcgacta tatcgtcgtg
     4441 caatttgacg gtgccggtag cgttaacgaa gaccctactg cccaaaacct gaaatatcat
     4501 attactggtc tggaaaacat tcgcgtgctg gattgcagcg tcaatttttc catttcaccg
     4561 gaaacacagg tgattgattt tggtaaattt aatttgctgg atatacgtcg ccacacaatg
     4621 tcgaaaacgt tcagtattaa aacgaccaag agccaaaacg atcaatgcac cgacggattt
     4681 aaagtcagtt cctcctttta taccgaagaa acgttggttg aagaagataa agcattgttg
     4741 attggtaatg gtctgaagct acgtttactg gatgaaaacg cctcgcctta taccttcaat
     4801 aaatatgctg aatacgccga tttcaccagt gacatgttgg tctacgaaaa aacctatacg
     4861 gctgaacttt cgtccattcc aggcaccccc atcgaggctg gccccttcga tacagtggtg
     4921 ctttttaaga ttaactataa ctgatttacc atgatgccct ttgccgccgg aaagggcatc
     4981 tctttcagaa aattgctgat tttccccttt tccttgattg ctgttatttt ttcctggccc
     5041 agctttcttt atgctgtatc gatacaccaa agagaaaata atgagggagc gaaggatgcc
     5101 agttttgcag tggggaatgt tatgtgtgct atcacttctc ctttctattg gtttcctcgc
     5161 ggtacatctc ccggcggcgc tattacttgg gccgatgatc gccgggatca tctttagtat
     5221 gcgcggaatt actctgcaac ttccccgctc tgcttttctc gccgcccagg ccattcttgg
     5281 ctgcatgatt gcgcaaaacc tcactggttc gattctcacc accctggccg tcaactggcc
     5341 gatcgtgctt gcaattttac tggtaacgct gctttccagc gccattgtgg gttggttatt
     5401 ggtgcgctat agctcattgc ctggaaatac cggtgcctgg ggctcctctc ctggcggcgc
     5461 ggcggcaatg gtcgctatgg cgcaagatta cggcgcagat attcgcctgg tggcgtttat
     5521 gcaatatctg cgagtgctgt tcgtcgcggg ggccgctgtt ctggtcaccc gcatgatgct
     5581 gggcgataac gctgaagcgg ttaaccagca tatcgtctgg ttcccgccag tgagcattaa
     5641 tctcctgctt actattttgc tcgcggtcgt tgccggtaca gtgggatgcc tgctgcgtct
     5701 tccttccggc acgatgctca tcccgatgct ggcgggcgca gtgctccagt ctggtcagct
     5761 catcaccatc gaactaccgg aatggctgct ggcgatggcg tatatggcaa ttggctggcg
     5821 gattggtctt ggtttcgata aacaaatctt actgcgggca ctacgcccgc taccgcaaat
     5881 cctgctgtcg atttttgctc tgctggctat ttgtgcgggt atggcgtggg ggctgacccg
     5941 gtttatgcac attgatttta tgactgccta cctcgccacc agccccggcg ggcttgatac
     6001 cgtggcggtc atcgccgcag ggagcaatgc cgatatggcg ctcattatgg cgatgcaaac
     6061 cctacgcctg ttcagtattt tgctgacagg gcctgccatt gcgcggttta tttcaaccta
     6121 tgcgccgaag cggtcggcct agtgctggca gccagggcac cagtaaaacg ggcgagatga
     6181 cagcgtggtt ttctcaatga tgctgccaca acgttcgcac ggttcgccat ctcgatgaaa
     6241 aaccttaaag cgaaacagcg ccccatgatg cttattctca tccacctgcc cccgcgtagc
     6301 gtaggaaaat cgaggaatct ccagtaacgc gtgtgcgagt gcatccagtt gcgccgcatt
     6361 gagatctttc gctttatgat ttccagtcaa cccaacctgc cagaggatct ccacccgcaa
     6421 ataattgcca agcccagcca gaaacgcctg atcgagcagt aatccagcaa actgacggtt
     6481 acgaaagcgc ggcgacaata atcgttcttt caccacctcc ggcgtcagat tcggatccag
     6541 cacatcggga ccaacgcgtt gtaaaaacgg atgcgtggtc agttgttccg gggtcaacat
     6601 ctcaatatcc gaggcgctat aaagcagaat ggttttgtca gccgtttgca gttttacccg
     6661 caatactcgc gtggtctgcg gctcttcgcc ggtatcaacc acgcgccaga cgccgtaaag
     6721 ctgattatgg ctgtagagcg ttaagtcgtt ggaaaaatga gttaacaacg ccttaccacg
     6781 cgtttccaca tgggtaacgt gttgaccgat aagttgtgat tgataaggtt ttaactgcgg
     6841 gaaggcaaac cagacatcag ttagtggttt gcctttgatc gccgcctcca ggttatccgc
     6901 tgcacggcgg atctccgggc cttcaggcat ggtgatatcc ttttttcatt ctttattaat
     6961 cggggttatg ctgcgacaac aatccccttt tcggcaaatg cagagcgtag tcggcgggcg
     7021 aacgccagtg cgtgctcgcc gtcgccatgc aggcagaccg tttgcgccgc gaccgttgcc
     7081 cattcgccgg tgatactttt gactctgccg tgttgcacca tctccagcgt ttgcgccagc
     7141 gcctgttctt cgttttcaat caacgcgcct gactggcttc gcggcaccag cgagccgtca
     7201 gcctgataac cgcgatcggc aaacacttcc tcgcgcgttg tcagaccata ttgcttgcct
     7261 gcacgaatca gctcgcttcc cgccagcccg acgagaatca atgctggatc gcaagcgtat
     7321 accgctctgg cgatggcgtc tgccagttgt gcttctttcg ccgcctggtt gtacaacatg
     7381 ccgtgcggtt tgacatgacg cattacgccg ccttgcgcac gggcaatcgt tgccagcgcg
     7441 ccaatttgat acagcgtctg ggcgtaaacg gtttctggcg gcagctgcat ggcgctgcga
     7501 ccaaaatttt ccctgtcggg aaaactcggg tgagcgccaa tcgcgacacc attttttatt
     7561 gcttcacgca cgcaagcctg catgatttgc gcatcgcctg catgaaatcc acaggcaata
     7621 ttggcagagg aaaccagcgt taatagctct gcgtcgctgg cgcagccttc gcccagatcg
     7681 gcgttcaggt caattttcat tgtgcagccg ccacgctaat tgttcaaaat aacgttgctg
     7741 atcttgccgt gcttttagtg cctcttccag tgaacactgg acaaaatgaa tcggctgacc
     7801 gagcggaatt tgcgccagat ggtacatatc agcctcaatg atacaggcaa tacgcgggta
     7861 accaccggtg gtctgtgcgt cgttcatcaa cacaatcggc tgcccgttat gtggcacctg
     7921 caccacgccc ggtaacaaac cgtgagataa cagttcgcga tcggtggtgc gttttaaaat
     7981 ttgcccctgt aagcgatagc ccatgcggtt actttgcgag ctaagctgcc agggcgaacg
     8041 ccagaatgca tcctgcgagg cgcgatcgaa ctcatgatat tccggccccg gcaaggcgcg
     8101 aatgcggttg ccccacagca gctgtttaac gccctgcgct tccatagaat cacgcttcga
     8161 tttgccaatc gggagtcggt caccatcctt cagtaaacgg ccttccagcc cgccaatccc
     8221 cactttgaga tcggtgctgc atgagcccat taccggcgga acatcaatac cacccgcgac
     8281 cgccagataa ctgcgcatcc cgtgctgcgg gcgtttaagc gttaaacgct ggcctgcttt
     8341 catcggcaat cgccagccgg tccagacggc attatcatcc agccgcgctt cgcaaccggc
     8401 acccgtcaga gcaaaccacc catcagtttc gaactcaaca gttaactgac cgagcgtgat
     8461 ctccagcgcg ggggcattgg cgtcattacc caccagtagg ttagcaatgc gtaacgcggg
     8521 catatccagt gcgccgcagt ggctgatacc cgactggcga aaaccgtgac gaccgccatc
     8581 ctgcacagtg gtatacatgc ccgcacgaat aatcttcagc atactccctc cttctgcggt
     8641 acaaagcgca cgctgtctcc cggacgtaat aagatgggtt cgtcacgcgc cggatcaaac
     8701 aggctgagtg aggtatgacc aatcaactgc cagccacccg gcgttgccag cggataaaca
     8761 ccagtctgcg gcccgccgat cccgacagaa cctgccggaa cgagtaagcg cggttcagcg
     8821 cgccgtggcg tgtgtagttg ttccggcaaa ctcccgagat acgggaagcc cggttgaaaa
     8881 cctaaaaacc agaccacgta ttccacggag gagtgcaatt caacaacctg tttttcgctc
     8941 aacccgcaat gcgccgcgac caccgccaaa tccggtccgc ctgcaccacc gtaaaccacc
     9001 ggaatttcaa taaagcgaga ctccggctcc agcgcctcgc tctcctccca ccagcgttgc
     9061 aaacgctcta tggcatccag cgccagcgac tcaggattac gcaaaatcac cgtgatattg
     9121 ttcatgccgg gaatggcttc aaccacattc ggcatatcca ccagacgctg cgccagtcgc
     9181 cagatccgtt tctggctagc cagcgtcacc ggcggttcca gttccagcac taccgccgtt
     9241 tcacctatca gataacaacg cgctcgttgc actttcgatc cctctgatta ttcgttatgc
     9301 aggattagga atatcaataa aggtcacatc aagatcggta ttttcattca gccactcgct
     9361 caatgcgcga ataccaccac gttcagtggc atggtgacct gcagcataaa aatgcaatcc
     9421 ctgctcgcgg gctgaatgaa tggtctgttc agaaacttcg ccagtaataa aagcatccac
     9481 gccaaaacgc gcggcgctat cgataaaact ttgcccgccg cccgtgcacc aggcgacgcg
     9541 ctggaccacc tcaggtccgg tatcgccaca ccataacggc ttacgtccca gacgcgcttc
     9601 aatccaggaa gccagctcca gtcccggcac aggcatggtc agttcgcccc acggcaccaa
     9661 cggctcaatt tcgcccatga ccgtgatccc cagtaacgcc gccagctgtg cgttattgcc
     9721 cagctcagga tgtgcgtcaa gcggcaaatg ccagccatac aggttgatat cattcgccag
     9781 caacgttttt aaacggttac gcttcattcc gcgaatgacc ggagactctc ctttccagaa
     9841 gtagccatga tgcacaatga ccgcatccgc gcccagacgc actgcctcat cgagcaaagc
     9901 ctggctggcg gtgacaccgg taacaatttt ttgcaccgtc tctttgcctt ccacctgcaa
     9961 accattcggc gcgtaatcac taatcgccgc gctgttcagt ttttcgttaa tcagttgttc
    10021 cagttcggtg tttttcatct tcgcgccttc cgtattctga tagctacacc gttaacatag
    10081 cgttacctcg ccagttcgtc gatagccaat cttttgacat attaagaaac aaacccgacg
    10141 ccaaaagacg caaattgttt atatcatcac gcttcagcta atgtatattt atgcaatcag
    10201 acagcatatt gcataaataa tcagatctgt atcaaagttt taactttaag gaaacacaag
    10261 cacgccgcgc aactattacg tgacgttgcc gtcaattgtg gaattattat gaataaacac
    10321 gcatcacagc cgcgcgctat ttactatgtc gttgcgctgc aaatctggga atattttagc
    10381 ttttacggca tgcgtgccct gctgattctc tatctcacca atcaactaaa atacaacgat
    10441 actcacgcct acgagttatt tagcgcctac tgttcgctgg tgtatgtcac gccaatcctc
    10501 ggtggctttt tggcggataa agttctcggc aatcgcatgg cggtgatgct gggggcgttg
    10561 ttgatggcga tcggtcatgt ggtgctgggt gccagtgaga tccatccgtc attcctctat
    10621 ctgtccctgg cgattatcgt ctgcggctat ggcctgttta aatctaacgt aagctgtctg
    10681 ctcggcgagc tgtatgagcc aaccgatccg cgtcgtgatg gcggtttctc gctgatgtat
    10741 gcggcgggta acgtggggtc tattatcgca cctatcgcct gtggttacgc ccaggaagag
    10801 tacagctggg cgatgggctt tggcctggcg gcggttggca tgatcgcggg tctggtcatt
    10861 ttcttatgtg gcaatcgtca tttcactcat acccgcggcg ttaacaaaaa agtactgcgt
    10921 gcgacaaact ttctcctgcc gaactgggga tggctgctgg ttctgctggt ggcaacgcct
    10981 gcactgatta ccatactgtt ctggaaagag tggtcggtat acgccttaat tgtcgcgact
    11041 attattggcc tgggtgtact ggcaaaaatt tatcgcaaag cagaaaacca gaaacagcgg
    11101 aaggagctgg ggctgattgt gacgctcacc ttcttcagta tgttgttctg ggccttcgca
    11161 caacagggcg gtagctcgat tagcctttat atcgaccgct tcgttaaccg cgatatgttt
    11221 ggttataccg ttccgaccgc gatgttccag tcgattaatg ccttcgcagt tatgctgtgc
    11281 ggtgtgttcc tggcgtgggt ggtaaaagag agtgtcgcgg gtaatcgtac cgtgcgcatc
    11341 tgggggaaat ttgctcttgg ccttggcctg atgagcgccg gattctgcat tctgacctta
    11401 agcgcccgct ggtccgcaat gtatggtcac tcttctctgc cactgatggt attaggcctg
    11461 gcggtgatgg gctttgcgga actgtttatc gacccggttg ccatgtcgca aattacgcgc
    11521 attgaaatcc ccggtgtgac cggcgtatta accggcatct acatgctgct ttctggcgcg
    11581 atcgcgaact atctggcggg cgtgattgcc gatcagacat cgcaggcttc gtttgatgct
    11641 tccggggcga tcaactactc catcaatgca tatattgaag tatttgatca aattacctgg
    11701 ggcgcactgg cgtgtgtagg actggtactg atgatttggc tgtatcaggc gctgaaattc
    11761 agaaaccgcg cgctggcgct ggagtcttaa taggccagca ccgatgcctg atgcgacgct
    11821 tgacgcgtct tatcaggcct acgtatttcc tgcaatttat tgaatttgca caaatttgta
    11881 ggctggataa ggcgttcacg ccgcatccgg catctgggct cgattgcctg acgcgtctgt
    11941 tatttcccct tccgcgccgc ctcatacgct gccaacgttt gtactctcgc ttctttgtgc
    12001 tcgactatcg gttgcggata atccagcgtc acacctgctt tctgcgccca cttccacggc
    12061 tcatgcacca ctttccctgg cacatcgcgc agttccggta gccactggcg gataaactcg
    12121 ccctcatgat caaatttctc gccctgggtt gtcgggttga aaatacgaaa atacggcgct
    12181 gcatcggttc cggttgaagc ggcccactgc cagccaccgt tattggctgc caaatcacca
    12241 tcaatcagct gcgacatgaa atatcgctcg ccttcgcgcc agtcgatcaa taaatctttc
    12301 accagaaaac tggctgtaat catccgtagc ctgttatgca tccagccagt gctgttaagc
    12361 tgacgcatag cggcatcaac aatcgggtat cccgttttgc cttcctgcca ggcctgtaaa
    12421 tgtgcgggat tgctctgcca ctgtacacga tccgtccagg caataaatgg acgatgttta
    12481 cacaacgagg ggtgatacgt tatcaggtga cggtaaaact cgcgccagat cagctcatta
    12541 agccagacac taccggcccc accgtccagc gcctgcggct gttcagccaa caagcgatgc
    12601 aagcactggc gaggcgataa cccgcccgtt gccaggctgg ccgacaaacg gctggtgcct
    12661 tccactgccg gaaaatctcg ttgttgctca tattctccgg caccgttctg gcaaaactgg
    12721 cgtaattgcg caatcgccgc tttttcttcc accggaaaat gcgcagtatc gaaagactga
    12781 cgaggataat tcagcgtaat ggatggcgag ggctctatcg atccgctact acgaactttt
    12841 ggcgcagcga cgcactccgg catcccttcc cgcagccgtt tcagccaggc attcttaaaa
    12901 ggcgtaaaga ctttgtacat ctcgtgatta ccggtcatca ccgcgccagg cggcaggatc
    12961 acgctgtcat caaatccttc acacaccacg ttacgcagcg ctctttcaac ttccacatcc
    13021 cgcgcccgct cattcacttc atactgatag ttataaaaca ggtgggtaac gctgttttcc
    13081 gcgcacacct gtttaactat ttcgacactg gcgacaaagt catccacttc acggaacaat
    13141 aaaggaatac ctttttccgc aagcgctatt tgtagcccat tcagttgagc attgataagt
    13201 tcagcctgac gcggcgacat gttatgcgtc gcccactggc gtggtgtagc gatatacaac
    13261 gccagcacgc gtgcagacga attgcggcag gcggcagcca gtgcgagatt atcgtgcaga
    13321 cgtaaatcct ggcgaaacca gaccagatgg gtagtcataa aactcctgaa tggcgcaagt
    13381 taatcacacg cggccaaagt tcgaaataac gctgccctga aagccaggcg tcaggataaa
    13441 gcgccatata gtgtttgata cgcatcagcg gcgcaagaag tggttgctcg ccacggcgat
    13501 aactgtcgat aagcgcagcc agctgctggc gttctgtgga atcaatatgc gggcgaaaat
    13561 aaccctgaac gtgcatcaaa acattggtgt gatcgcgcgg gttggcgggg tgagaaagca
    13621 aaacaactac gcgttggcgg tactggttgt aatagtcatc cagattttgc cactggtgaa
    13681 tatcagccac gaacgggcca agtttgcggt actccggctg agaatgcgcc agaaagacga
    13741 gtttatagcg gctgtgataa tcgagaagcg ccccgcgcgt taagccatgt tctttcagtc
    13801 gatgtaactc atgaagggca aagatacgga ttagggtgct gtcatcaaat cgttgtagat
    13861 tcattactgc tcctgagcgg tttacaggag taagtgtaga cgttgagaaa tgatatttgt
    13921 gaagttaatc ctgttgtagc aggacaaatt tacgaaagcc tgctccccgc aaggactgac
    13981 gtcaggtagt ttctaaccat agctgccctt tctattcaaa cgtgaaatca ataagctcat
    14041 cagggacatc gcaaacaata tgaagacggg tttcttctct gccgtgactc ttttcactaa
    14101 ttgcgtaact gtcatgcttg ggattattta attctttcag cggaaatttt tcctcgaagg
    14161 ctttatttag ccgcccctgg tttcctttta cagcgaataa ataatcacct ccctgttttt
    14221 gtatcttctc tgcaatatct ttctggcaac ccatcgcatc ggttttgatg atttttcctt
    14281 taatatccag catgttaaga agttcaggga tagctgtgat ctcattggat ttcttatccg
    14341 tcttgatctg tccgatgacc agactgtgca ttgttgagaa cgcactaatg acatgaatcg
    14401 ctcccttacg gcgactcttg tcataagaat gccggtgtat ttttccatca attgcgatga
    14461 cgtctttatc atctgaagaa tggtagtcaa gcatccagtt aataaagctc tcatgaaatt
    14521 tcgcaggaca gatacaggat acaactctgg caatggtatc gtgaacagga ataccatttt
    14581 caaaatcacc atattgcttc aaaaaatcgg gatgtgtttc cccaaaatcc tctatatct
//
LOCUS       DAPOAV010000097        14130 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.097, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000097 DAPOAV010000000
VERSION     DAPOAV010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14130
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.097"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..677
                     /gene="gspC"
                     /locus_tag="RN951_003640"
     CDS             <1..677
                     /gene="gspC"
                     /locus_tag="RN951_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type II secretion system protein GspC"
                     /protein_id="HDX2528584.1"
                     /translation="IINQPTNAFQSDFSLAALWRNENHAGVKDANPVAVNQETPKLSI
                     ALNGIVLTSNDETSFVLINEGSEQKRYSLNEALESAPGTFIRKINKTSVVFETHGHYE
                     KVTLHPGLPDIIKQPDSESQNVLADYIIATPIRDGEQIYGLRLNPRKGLNAFTTSLLQ
                     PGDIALRINNLSLTHPDEVSQALSLLLTQQSAQFTIRRNGVPRLINVSVGELTGMNGL
                     RHERTQ"
     gene            661..2613
                     /gene="gspD"
                     /locus_tag="RN951_003641"
     CDS             661..2613
                     /gene="gspD"
                     /locus_tag="RN951_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417784.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system secretin GspD"
                     /protein_id="HDX2528585.1"
                     /translation="MKGLNKITCCLLAALLMPCAGHAENEQYGANFNNADIRQFVEIV
                     GQHLGKTILIDPSVQGTISVRSNDTFSQQEYYQFFLSILDLYGYSVITLDNGFLKVVR
                     SANVKTSPGMIADSSRPGVGDELVTRIVPLENVPARDLAPLLRQMMDAGSVGNVVHYE
                     PSNVLILTGRASTINKLIEVIKRVDVIGTEKQQIIHLEYASAEDLAEILNQLISESHG
                     KSQMPALLSAKIVADKRTNSLIISGPEKARQRITSLLKSLDVEESEEGNTRVYYLKYA
                     KATNLVEVLTGVSEKLKDEKGNARKPSSSGAMDNVAITADEQTNSLVITADQSVQEKL
                     ATVIARLDIRRAQVLVEAIIVEVQDGNGLNLGVQWANKNVGAQQFTNTGLPIFNAAQG
                     VADYKKNGGITSANPAWDMFSAYNGMAAGFFNGDWGVLLTALASNNKNDILATPSIVT
                     LDNKLASFNVGQDVPVLSGSQTTSGDNVFNTVERKTVGTKLKVTPQVNEGDAVLLEIE
                     QEVSSVDSSSNSTLGPTFNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVPLLGDI
                     PLVGQLFRYTSTERAKRNLMVFIRPTIIRDDDVYRSLSKEKYTRYRQEQQQRIDGKSK
                     ALVGSEDLPVLDENTFNSHAPAPSSR"
     gene            2623..4104
                     /gene="gspE"
                     /locus_tag="RN951_003642"
     CDS             2623..4104
                     /gene="gspE"
                     /locus_tag="RN951_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system ATPase GspE"
                     /protein_id="HDX2528586.1"
                     /translation="MRIHSPYPASWALAQRIGYLYSEGEIIYLADTPFERLLDIQRQV
                     GQCQTMTSLSQADFEARLEAVFHQNTGESQQIAQDIDQSVDLLSLSEEMPANEDLLNE
                     DSAAPVIRLINAILSEAIKETASDIHIETYEKTMSIRFRIDGVLRTILQPNKKLAALL
                     ISRIKVMARLDIAEKRIPQDGRISLRIGRRNIDVRVSTLPSIYGERAVLRLLDKNSLQ
                     LSLNNLGMTAADKQDLENLIQLPHGIILVTGPTGSGKSTTLYAILSALNTPGRNILTV
                     EDPVEYELEGIGQTQVNTRVDMSFARGLRAILRQDPDVVMVGEIRDTETAQIAVQASL
                     TGHLVLSTLHTNSASGAVTRLRDMGVESFLLSSSLAGIIAQRLVRRLCPQCRQFTPVS
                     PQQAQMFKYHQLAVTTIGTPVGCPHCHQSGYQGRMAIHEMMVVTPELRAAIHENVDEQ
                     ALERLVRQQHKALIKNGLQKVISGDTSWDEVMRVASATLESEA"
     gene            4101..5297
                     /gene="gspF"
                     /locus_tag="RN951_003643"
     CDS             4101..5297
                     /gene="gspF"
                     /locus_tag="RN951_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system inner membrane protein
                     GspF"
                     /protein_id="HDX2528587.1"
                     /translation="MNYRYRAMTQDGQKLQGIIDANDERQARLRLREEGLFLLDIRPQ
                     KSSGVKTRRPRISHSELTLFTRQLATLSAAALPLEESLAVIGQQSSNKRLGDVLNQVR
                     SAILEGHPLSDALQHFPTLFDSLYRTLVKAGEKSGLLAPVLEKLADYNENRQKIRSKL
                     IQSLIYPCMLTTVAIGVVIILLTAVVPKITEQFVHMKQQLPLSTRILLGLSDTLQRIG
                     PTLLATVFIVAVGFWLWLKRGNNRHRFHAMLLRVALIGPLICAINSARYLRTLSILQS
                     SGVPLLDGMNLSTESLNNLEIRQRLANAAENVRQGNSIHLSLEQTAIFPPMMLYMVAS
                     GEKSGQLGTLMVRAADNQETLQQNRIALTLSIFEPALIITMALIVLFIVVSVLQPLLQ
                     LNSMIN"
     gene            5307..5744
                     /gene="gspG"
                     /locus_tag="RN951_003644"
     CDS             5307..5744
                     /gene="gspG"
                     /locus_tag="RN951_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system major pseudopilin GspG"
                     /protein_id="HDX2528588.1"
                     /translation="MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQK
                     AVSDIVALENALDMYKLDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADP
                     WGNDYVLVNPGEHGAYDLLSAGPDGEMGTEDDITNWGLSKKKK"
     gene            5752..6261
                     /gene="gspH"
                     /locus_tag="RN951_003645"
     CDS             5752..6261
                     /gene="gspH"
                     /locus_tag="RN951_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspH"
                     /protein_id="HDX2528589.1"
                     /translation="MNQQRGFTLLEMMLVLALVAITASVVLFTYGREDVASTRARETA
                     ARFTAALELAIDRATLSGQPVGIHFSDSAWRIMVPGKTPSAWRWVPLQEDAADESQND
                     WDEELSIHLQPFKPDDSNQPQVVILADGQITPFSLLMANAGTGEPLLTLVCSGSWPLD
                     QTLARDTRP"
     gene            6258..6635
                     /gene="gspI"
                     /locus_tag="RN951_003646"
     CDS             6258..6635
                     /gene="gspI"
                     /locus_tag="RN951_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417789.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspI"
                     /protein_id="HDX2528590.1"
                     /translation="MNKQSGMTLLEVLLAMSIFTAVALTLMSSMQGQRNAIERMRNET
                     LALWIADNQLQSQDSFGEENTSSSGKELINGEEWNWRSDIHSSKDGTLLERTITVTLP
                     SGQTTSLTRYQSIDNKSGQAQDD"
     gene            6628..7215
                     /gene="gspJ"
                     /locus_tag="RN951_003647"
     CDS             6628..7215
                     /gene="gspJ"
                     /locus_tag="RN951_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspJ"
                     /protein_id="HDX2528591.1"
                     /translation="MINRQQGFTLLEVMAALAIFSMLSVLAFMIFSQASELHQRSQKE
                     IQQFNQLQRTITILDNDLLQLVARRNRSTDKIMVLGEEAIFTTQSRDPLAPLSEAQTL
                     LTVHWYLRNHTLYRAVRTSVDGRKDQPAQAMLEHVESFLLESNSGESQELPLSVTLHL
                     QTQQYGGLQRRFALPEQLAREESPAQTQAGNNNHE"
     gene            7208..8191
                     /gene="gspK"
                     /locus_tag="RN951_003648"
     CDS             7208..8191
                     /gene="gspK"
                     /locus_tag="RN951_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspK"
                     /protein_id="HDX2528592.1"
                     /translation="MNNEQRGVALLIVLMLLALMAALAADMTLSFHSQLQRTRQVNHH
                     LQRQYDIELAEKLALASLTQDVKDNDRQTTLQQYWAQPQQLQLEDGNTVKWQLRDAQH
                     CFNLNALAKISDDPLASPDFPAQVFSALLINAGIDRGNTDEIVQSIADYIDVDDSPRF
                     HGAEDSFYQSQTPPRHSANQMLFLTGELRQIKGITENIYQRLIPYVCVLPTTELSINL
                     NMLTENDIPLFRALFLNNITDADARVLLQKRPREGWLTTDAFLYWAQQDFSGVKPLVA
                     QVKRHLFPYSRYFTLSTESISDEQSQGWQSHIFFNRKQQSAQIYRRTLQLY"
     gene            8206..9369
                     /gene="gspL"
                     /locus_tag="RN951_003649"
     CDS             8206..9369
                     /gene="gspL"
                     /locus_tag="RN951_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417792.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspL"
                     /protein_id="HDX2528593.1"
                     /translation="MPESLMVIRSSSTLRKHWEWMTFSADSVSSVHTLTDDLPLESLA
                     DQPGAGNVHLLIPPEGLLYRSLTLPNAKYKLTAQTLQWLAEETLPDNTQDWHWTVVDK
                     QNESVEVIGIQSEKLSRYLERLHTAGLNVTRVLPDGCYLPWEVDSWTLVNQQTSWLIR
                     SAAHAFNELDEHWLQHLAAQFPPENMLCYGVVPHGVAAANPLIQHPEIPSLSLYSADI
                     AFQRYDMLHGIFRKQKTVSKSGKWLARLAVSCLVLAILSFVGSRSIALWHTLKIEDQL
                     QQQQQETWQRYFPQIKRTHNFRFYFKQQLAQQYPEAVPLLYHLQTLLLEHPELQLMEA
                     NYSQKQKSLTLKMSAKSEANIDRFCELTQSWLPMEKTEKDPVSGVWTVRNSGK"
     gene            9366..9827
                     /gene="gspM"
                     /locus_tag="RN951_003650"
     CDS             9366..9827
                     /gene="gspM"
                     /locus_tag="RN951_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417793.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspM"
                     /protein_id="HDX2528594.1"
                     /translation="MIKSWWAEKSTSEKQIVAALAVLSLGVFCWLGVIKPIDTYIAEH
                     QSHAQKIKKDIKWMQDQASTHGLLGHPALTQPIKNILLEEAKRENLAITLENGPDNTL
                     TIHPVTAPLENVSRWLTTAQVTYGIVIEDLQFTLAGNEEITLRHLSFREQQ"
     gene            9827..10504
                     /gene="gspO"
                     /locus_tag="RN951_003651"
     CDS             9827..10504
                     /gene="gspO"
                     /locus_tag="RN951_003651"
                     /EC_number="3.4.23.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase GspO"
                     /protein_id="HDX2528595.1"
                     /translation="MTMLLPLFILVGFIAGYFVNAIAYHLSPLEDKTALTFRQVLVHF
                     RQKKYAWHDTVPLILCVAAAIACALAPFTPIVTGALFLYFCFVLTLSVIDFRTQLLPD
                     KLTLPLLWLGLVFNAQYGLIDLHDAVYGAVAGYGVLWCVYWGVWLVCHKEGLGYGDFK
                     LLAAAGAWCGWQTLPMILLIASLGGIGYAIVSQLLQRRTITTIAFGPWLALGSMINLG
                     YLAWISY"
     gene            complement(10533..11009)
                     /gene="bfr"
                     /locus_tag="RN951_003652"
     CDS             complement(10533..11009)
                     /gene="bfr"
                     /locus_tag="RN951_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin"
                     /protein_id="HDX2528596.1"
                     /translation="MKGDTKVINYLNKLLGNELVAINQYFLHARMFKNWGLKRLNDVE
                     YHESIDEMKHADRYIERILFLEGLPNLQDLGKLNIGEDVEEMLRSDLALELDGAKNLR
                     EAIGYADSVHDYVSRDMMIEILRDEEGHIDWLETELDLIQKMGLQNYLQAQIREEG"
     gene            complement(11081..11275)
                     /gene="bfd"
                     /locus_tag="RN951_003653"
     CDS             complement(11081..11275)
                     /gene="bfd"
                     /locus_tag="RN951_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin-associated ferredoxin"
                     /protein_id="HDX2528597.1"
                     /translation="MYVCLCNGISDKKIRQAVRQFSPHSFQQLKKFIPVGNQCGKCVR
                     AAREVMEDELMQLPEFKESA"
     gene            complement(11444..14110)
                     /gene="chiA"
                     /locus_tag="RN951_003654"
     CDS             complement(11444..14110)
                     /gene="chiA"
                     /locus_tag="RN951_003654"
                     /EC_number="3.2.1.14"
                     /EC_number="3.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001338749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chitinase/lysozyme"
                     /protein_id="HDX2528598.1"
                     /translation="MIGMGLVCSALPALAMEAWNNQQGGNKYQVIFDGKIYENAWWVS
                     STNCPGKAKANDATNPWRLKRTATAAEISQFGNTLSCEKSGSSSSSNSNTPASNTPAN
                     GGSATPAQGTVPSNSSVVAWNKQQGGQTWYVVFNGAVYKNAWWVASSNCPGDAKSNDA
                     SNPWRYVRAATATEISETSNPQSCTSAPQPSPDVKPAPDVKPAPDVQPAPADKSNDNY
                     AVVAWKGQEGSSTWYVIYNGGIYKNAWWVGAANCPGDAKENDASNPWRYVRAATATEI
                     SQYGNPGSCSVKPDNNGGAVTPVDPTPETPVTPTPDNSEPSTPADSVNDYSLQAWSGQ
                     EGSEIYHVIFNGNVYKNAWWVGSKDCPRGTSAENSNNPWRLERTATAAELSQYGNPTT
                     CEIDNGGVIVADGFQASKAYSADSIVDYNDAHYKTSVDQDAWGFVPGGDNPWKKYEPA
                     KAWSASTVYVKGDRVVVDGQAYEALFWTQSDNPALVANQNATGSNSRPWKPLGKAQSY
                     SNEELNNAPQFNPETLYASDTLIRFNGVNYISQSKVQKVSPSDSNPWRVFVDWTGTKE
                     RVGTPKKAWPKHVYAPYVDFTLNTIPDLAALAKNHNVNHFTLAFVVSKDANTCLPTWG
                     TAYGMQNYAQYSKIKALREAGGDVMLSIGGANNAPLAASCKNVDDLMQHYYDIVDNLN
                     LKVLDFDIEGTWVADQASIERRNLAVKKVQDKWKSEGKDIAIWYTLPILPTGLTPEGM
                     NVLSDAKAKGVELAGVNVMTMDYGNAICQSANTEGQNIHGKCATSAIANLHSQLKGLH
                     PNKSDAEIDAMMGTTPMVGVNDVQGEVFYLSDARLVMQDAQKRNLGMVGIWSIARDLP
                     GGTNLSPEFHGLTKEQAPKYAFSEIFAPFTKQ"
BASE COUNT         3619 a         3648 c         3386 g         3477 t
ORIGIN      
        1 agatcattaa tcaaccaaca aacgcatttc agtctgattt cagccttgcc gctttatggc
       61 gtaacgaaaa tcatgctggg gtaaaagatg caaatcccgt ggcagttaat caggaaacac
      121 ctaagctctc tatagcgctt aatggcattg tactcacatc gaatgatgag acttcttttg
      181 tcttaattaa tgaggggagc gaacaaaagc gatactccct caacgaagcc cttgagtcag
      241 cgccgggaac gtttattaga aaaataaata aaaccagcgt tgtgtttgaa actcacgggc
      301 attacgaaaa agtaactctc catccagggc tacctgacat catcaagcag cctgattcag
      361 aaagtcaaaa tgtactcgct gattatatta tcgccacgcc tatacgtgat ggagaacaga
      421 tatacgggct tcgattgaac cctcgtaagg gcctcaatgc atttaccacc agcttgctac
      481 aaccagggga tatcgccctc aggatcaata atctttcgct gacccaccct gatgaggttt
      541 cacaggcatt aagtttactg ctaactcaac aaagtgctca gtttacaatt cgtcgcaacg
      601 gcgtaccccg cttgataaat gtttccgtcg gggaacttac aggaatgaat ggactgcgtc
      661 atgaaaggac tcaataaaat cacctgctgc ttgctggcag cactactcat gccttgtgca
      721 ggacacgctg agaacgaaca atacggcgcg aacttcaata acgccgatat ccgccagttc
      781 gtggaaatag tgggtcagca tcttggcaaa acgatcctga tcgacccttc ggtacaggga
      841 accatttccg tacgcagtaa tgatacgttt agccaacagg agtactacca gttcttttta
      901 agtattcttg atctttacgg ttattccgtg atcacgctgg acaatggttt tctgaaagtg
      961 gttcgctcag ctaatgtaaa aacatcgcca gggatgattg ctgacagttc tcgtccaggc
     1021 gtaggtgatg agttggtcac ccgaattgta ccgcttgaga acgttcctgc tcgtgacctg
     1081 gcccccctgc tccgccagat gatggatgcg ggtagcgtcg gtaatgttgt gcattatgaa
     1141 ccctccaacg ttcttattct gaccggtcgt gcctccacca ttaataaact gattgaagtc
     1201 ataaagcgcg ttgatgtcat cggcacagag aagcagcaaa ttattcatct ggaatatgcg
     1261 tcagcggaag atctcgccga gattcttaat caattaatca gcgaaagcca cggtaaaagc
     1321 cagatgccag ccctcctctc cgcgaagatt gtggcggata agcgaaccaa ctctcttatc
     1381 atcagtggac cggaaaaagc acgccagcgc atcacttcat tactgaaaag ccttgatgtc
     1441 gaagagagcg aggaaggaaa tacccgggtt tattacctga aatatgctaa agccacgaat
     1501 ctggtggaag tgctaaccgg tgtttccgaa aagctgaaag atgaaaaagg gaatgcgcgt
     1561 aagccctcct cttctggcgc gatggataac gtcgccatta ccgccgatga acagactaac
     1621 tctctggtca ttaccgctga ccagtccgtc caggaaaaac tcgccacggt aattgcgcgt
     1681 ctggacattc gccgtgcaca ggtgctggtt gaggcaatca tcgttgaagt tcaggatgga
     1741 aatggactaa acctcggcgt gcaatgggcg aataaaaacg ttggcgcaca gcaatttacc
     1801 aataccggat taccgatttt taacgctgcg caaggtgtgg ctgattataa aaagaatggt
     1861 gggatcacca gcgcgaatcc tgcctgggat atgtttagcg cctacaatgg catggccgca
     1921 ggcttcttca atggcgactg gggagtactg cttaccgcgc tggccagtaa caataaaaat
     1981 gacatcctcg ccaccccaag catcgtaacg ctggataata aactcgcgtc cttcaacgtg
     2041 gggcaggatg tgccggtgct atccgggtca cagaccactt caggggataa cgtctttaat
     2101 accgtcgaac gcaaaacggt ggggacaaaa ctcaaagtta ctccgcaggt caatgaaggc
     2161 gacgcggtgt tgctcgaaat agagcaggaa gtctccagcg ttgactcttc ctctaactcg
     2221 acgctcggcc cgacgtttaa tacccgtact attcaaaacg ccgtgctggt caaaaccggt
     2281 gaaacggtgg tcctgggcgg attgctggat gatttttcta aagagcaagt gtcaaaggtt
     2341 cctctgcttg gcgatattcc tttagtgggg caactcttcc gctatacctc caccgagcgc
     2401 gctaaacgca acctgatggt atttatccgt ccgacgatta tccgtgacga tgatgtttat
     2461 cgctcactgt caaaagagaa atacacccgt taccgtcagg agcaacaaca gcggatcgac
     2521 gggaaatcaa aagcgctggt tggctcggaa gatttgccgg tgctggatga aaacacgttc
     2581 aacagtcacg cccctgcgcc atcgtcacgg tgaggcattc atatgagaat tcactcaccg
     2641 taccccgcca gttgggcgct ggcacaacga attggttatc tctattcaga gggcgagatt
     2701 atttatctcg ccgatacgcc attcgagcgg ttactcgata ttcaacgtca ggttggccag
     2761 tgccagacca tgaccagctt gtcacaggct gattttgaag ctcggctgga agcggtattc
     2821 catcagaata ccggtgagtc gcaacagatt gcgcaggata tcgatcaatc cgtcgatctt
     2881 ctctcgcttt cggaagagat gcccgcaaat gaagatctcc tgaatgaaga ttcagcggca
     2941 ccggttatcc gcttgatcaa tgcgattttg agtgaggcca tcaaagaaac cgcctctgat
     3001 atccacattg aaacctatga aaaaacaatg tcgatccgtt ttcgcatcga cggcgttttg
     3061 cggacaattt tacagccaaa caaaaaactg gcggcactgc ttatctcccg aattaaggtc
     3121 atggctcgtc ttgatatcgc cgaaaaacgt attccacagg atggaagaat tagtttgcgt
     3181 atcgggcgac gtaacataga tgtccgcgta tccacactgc cgtccatcta tggtgaacgc
     3241 gccgtactcc gcctgctgga taaaaacagc ctccagcttt cattgaacaa cctggggatg
     3301 acggcagcgg ataagcagga tttagaaaat ctcattcagc ttccgcacgg tattatcctg
     3361 gtgacagggc cgacaggctc cggtaaaagc accacgctct acgccatcct ttcggcgctg
     3421 aatactcccg gccgcaatat tctgacggta gaagatcccg tggaatatga gctggaaggc
     3481 attgggcaaa cgcaggtgaa tacccgtgtg gatatgtctt tcgctcgcgg cctgcgcgcc
     3541 atacttcgcc aggatccgga tgtcgtcatg gtgggggaaa ttcgtgatac agaaaccgcg
     3601 cagattgcgg ttcaggcctc gctcaccggc catctggtac tctcaacact ccacactaac
     3661 agtgcatcag gcgcagtgac ccggctccgc gacatgggcg tcgaatcatt cctgctttcg
     3721 tcttccctgg cagggattat cgcgcaacgt ctggttcgtc gcctgtgtcc gcaatgccga
     3781 caattcacgc ccgtatcacc ccaacaagcg cagatgttta aatatcatca gctcgcggtg
     3841 acaacaattg gcactcccgt aggctgccct cattgccatc aatccggcta tcaggggcgc
     3901 atggcgatcc acgaaatgat ggtggtgacg ccggaattac gggccgctat tcatgaaaat
     3961 gtggatgaac aagcactgga gcgactagtc cggcaacaac acaaggcctt aatcaaaaat
     4021 ggcctgcaaa aagtgataag cggtgacacc tcctgggatg aggttatgcg cgtcgccagt
     4081 gccacgctgg agagcgaagc atgaattatc gctatcgcgc catgacccag gatggtcaaa
     4141 aattgcaagg gatcattgat gctaacgatg aacgtcaggc acgactgcgg ctgcgtgaag
     4201 aagggctttt cctgctggat attcgccccc aaaaaagttc gggagtaaaa acacgtcgcc
     4261 cgaggatcag ccatagtgaa ctgacgcttt tcacccggca gttggcaacc ttaagcgcag
     4321 cggcattacc cctggaagag agccttgccg taatcggtca acaaagcagt aataaacgac
     4381 tgggtgacgt gttaaatcag gtacgcagcg ccatccttga agggcatccc ctttccgatg
     4441 cattacagca ttttcccacg cttttcgatt cgctctatcg taccctggta aaagcgggcg
     4501 aaaagagcgg gctgctggcc ccggtgttgg aaaagctggc tgattacaat gaaaaccggc
     4561 agaaaatccg cagcaagctc attcagtcac tgatctaccc ctgtatgctc actacggtgg
     4621 cgattggggt cgtgattatt ctcctcactg ctgtcgtgcc caaaattacc gaacagttcg
     4681 tgcatatgaa gcagcaactg ccgctgagta cacgcattct tttaggtctg agcgacacgt
     4741 tgcaacgtat cggcccgaca ttattagcga cagtgtttat tgtcgctgta ggtttctggc
     4801 tctggttaaa acgcggcaat aaccgccacc gttttcatgc catgttgctg cgcgttgcgc
     4861 tcatcggccc gctgatttgc gccattaaca gcgcacgcta tctccgcact ttaagtattt
     4921 tgcaatccag cggcgtccct ctgctggatg ggatgaattt gtccaccgaa agcctcaaca
     4981 acctcgaaat tcgccagcgt ctggcaaatg cggcagagaa cgttcgccag ggtaacagca
     5041 ttcatctttc gctggaacaa accgcaattt tcccgccgat gatgctctac atggtggcct
     5101 ctggcgaaaa aagcgggcag ctcggcacat taatggtcag agccgcagat aaccaggaga
     5161 cactccaaca aaatcggatc gccttaacgc tctccatctt cgagccagca ctcattatta
     5221 cgatggcact gatcgtcctg tttattgtcg tgtcggtact ccaacctctt cttcaactta
     5281 actcaatgat taattaagga aagcatatgc gcgcaacgga taagcaacgc ggttttacat
     5341 tactggaaat tatggtggtg atcgtcatta tcggcgtact tgccagcctg gtggttccta
     5401 acctaatggg caataaagaa aaggcggata agcaaaaagc cgtcagcgat attgtggcgc
     5461 tggaaaacgc ccttgatatg tacaaactcg acaatcatca ctatccaacc acaaatcagg
     5521 ggcttgaatc cttagtagaa gcgccgacac tgccaccgct ggccgcaaac tataacaagg
     5581 aaggttatat caagcgtctg cctgccgatc cctggggcaa tgattatgtc ctcgttaatc
     5641 ctggtgaaca tggtgcatac gatctgcttt cagcagggcc cgatggtgaa atgggaaccg
     5701 aggacgacat caccaactgg ggtttgagca agaagaaaaa gtaagtcagc gatgaatcag
     5761 caacgcgggt ttaccctgct ggagatgatg ctggtgctgg cgctggtcgc tatcacggca
     5821 agcgtggtgc tcttcacata tggccgggag gatgtcgcca gcactcgtgc gcgcgaaaca
     5881 gcggcgcggt ttaccgctgc acttgaatta gccatcgacc gcgccacgct cagtggtcag
     5941 cctgtcggta tccatttctc tgattcagca tggcgcatta tggtaccggg caaaacacca
     6001 tcagcctggc gctgggttcc attacaagaa gatgccgcag acgagagcca aaatgactgg
     6061 gatgaagaac tctcaattca tcttcagcca tttaaacctg atgacagcaa ccagccacag
     6121 gttgtgattc tggccgacgg acaaatcacg cccttctctt tgttgatggc taacgccggg
     6181 accggtgagc cgctcctgac gttagtctgt tcaggctcat ggcccctgga tcaaacgctc
     6241 gccagagata cccgcccatg aacaaacaat cagggatgac actgcttgaa gtcttactgg
     6301 cgatgagtat tttcaccgct gttgctctga ctttaatgag cagtatgcaa gggcaacgaa
     6361 atgccatcga gcgaatgcgt aacgagacgc tggcattgtg gatagcggat aaccagcttc
     6421 agtcacaaga ttcattcggc gaggaaaaca cgtccagttc tggcaaagag ttaataaatg
     6481 gcgaagagtg gaactggcgc agcgatatcc actcaagcaa agacggcacg cttctggaac
     6541 gcaccataac ggtgacatta cccagcggtc agacaacctc gcttacgcgt tatcaaagca
     6601 tcgataataa atccgggcag gcacaagatg attaatcgcc agcagggttt cacattgctg
     6661 gaggtcatgg cggcgctggc gattttctca atgcttagcg tgctggcgtt tatgattttt
     6721 tcgcaagctt ccgagttgca tcaacgctca cagaaagaaa tccagcagtt caatcagcta
     6781 cagcgcacca tcaccattct tgataacgat ctcctgcaac tggtcgcccg gaggaatcgg
     6841 agtacggaca aaatcatggt gttgggtgaa gaagctattt ttaccacgca aagtcgcgat
     6901 ccgctggctc ctctcagtga agcacaaacc ttactcactg ttcactggta tctgcgaaat
     6961 catacgctct accgtgctgt tcgtacttct gtggatggca ggaaggatca acccgcccag
     7021 gcgatgctgg aacatgtcga gagctttctt ctggaaagta acagcgggga aagccaggaa
     7081 cttcctctct cagtcacgtt acatctgcag actcagcaat atggggggtt acagcgccgt
     7141 tttgcattac ctgagcagtt agcgagagaa gagtcgccag ctcagacgca ggccgggaat
     7201 aataaccatg aataatgaac aacgcggcgt cgcgctgctc attgtactca tgttactggc
     7261 gctcatggct gctctggcag cagacatgac gctcagtttt cacagccagc ttcagcgaac
     7321 ccgccaggta aaccatcatc tgcaacggca atatgatatt gaactggcgg agaaacttgc
     7381 gcttgccagc ctcacccagg acgttaaaga taacgacaga cagaccacgt tgcagcagta
     7441 ctgggcacag ccacaacagt tgcagctgga agatggcaat acagtgaagt ggcagttacg
     7501 cgatgcccag cactgtttta atctcaatgc gttagcaaaa atctctgacg acccgctggc
     7561 ttcccctgat ttccccgccc aggtattcag tgcgctgctg attaacgccg gtatcgatcg
     7621 cggaaacacc gatgagatcg tgcaatcaat cgctgactat attgatgtcg atgactcacc
     7681 acgctttcac ggcgcagaag atagctttta ccaaagccag acgccgcccc ggcatagtgc
     7741 caatcagatg ctttttctga ctggcgaatt acgtcagata aaaggcataa ccgaaaacat
     7801 ctatcagcgg cttatcccgt atgtctgcgt tctcccgacc acggaactta gcatcaatct
     7861 taatatgcta acggagaacg atattccgct cttcagagcg ttattcctca ataacatcac
     7921 ggatgctgac gctcgggtct tattgcaaaa aaggccgagg gaaggctggc taaccacgga
     7981 tgcatttctt tactgggcgc agcaggattt ctccggtgtg aagccactgg ttgctcaggt
     8041 gaaaaggcat ctctttccct atagccgcta ttttacgctg agtacggaaa gtatcagcga
     8101 cgaacaatcc cagggatggc aaagccatat ttttttcaac cgtaaacagc agagcgccca
     8161 aatctatcgg cgtacgctgc aactctacta atcataagga tcgtgatgcc tgaatcgttg
     8221 atggtcatac gttcttcctc gacgctgcgt aagcattggg aatggatgac gttctccgca
     8281 gatagcgtat cttcggtaca tacgctcacg gacgatcttc cgctggagtc gctggccgat
     8341 cagcccggtg ccggaaatgt tcatcttttg atcccaccag agggcctttt atatcgttcc
     8401 ctcacgctgc ccaacgccaa atacaaactc accgcacaaa cattacaatg gctggcagag
     8461 gagacgttac ccgacaacac ccaggactgg cactggacgg ttgtcgataa acaaaacgaa
     8521 agtgtcgagg tgataggcat tcagtcggag aaactcagtc gctatcttga gcgtttacat
     8581 actgccggac tcaacgtgac gcgggttttg ccagatggct gctatcttcc ctgggaagta
     8641 gatagctgga ctctggttaa ccagcaaaca agctggctca ttcgcagtgc cgcacatgcc
     8701 ttcaacgaac tggatgaaca ctggttacag catcttgctg cccagtttcc gcctgagaat
     8761 atgctttgtt atggtgtagt acctcacggc gttgcagcgg ccaatccact tatccagcat
     8821 cctgaaatac catcactgag tttgtattct gccgatattg cattccagcg ctatgacatg
     8881 ctgcatggta tttttcgtaa acagaaaact gtaagcaaat cgggaaaatg gctcgcccgc
     8941 ctggcagtaa gctgtctcgt tctcgccatt ctttcttttg ttggcagccg gagcatcgcg
     9001 ctctggcata cgcttaagat tgaagatcaa cttcagcaac aacagcaaga aacctggcaa
     9061 cgttatttcc cgcagatcaa acgcacccac aattttcgtt tttactttaa gcagcaactc
     9121 gctcagcaat atcctgaagc tgtgccgttg ctctatcatt tacaaacact tctgctggaa
     9181 caccctgaac tgcagttaat ggaggcgaac tatagccaga agcaaaagtc gctgacctta
     9241 aaaatgagtg ctaagagtga agctaatatc gatcgtttct gtgagttaac acagtcctgg
     9301 cttccgatgg aaaaaacaga aaaagatccg gtcagtggtg tatggacagt aaggaactca
     9361 gggaaatgat taaatcatgg tgggcagaaa aatccacatc ggaaaaacag atcgttgcgg
     9421 cactggcggt tctctcgctc ggcgtttttt gttggcttgg ggtgataaaa ccgatagata
     9481 cctacattgc agagcatcag tcccacgcgc aaaaaattaa gaaggacatc aaatggatgc
     9541 aggatcaagc gagcacccat ggtttactcg gtcatcctgc gcttacgcag cccatcaaaa
     9601 atatccttct cgaggaagca aaacgtgaga atttggctat cacgctggaa aacggcccgg
     9661 acaatactct gacaattcat cctgtcacag ctcccctcga aaacgtctcc cgctggctca
     9721 ctacggcaca ggtaacatac ggtattgtta ttgaagacct tcagtttact cttgccggaa
     9781 acgaagagat caccctcagg catttgtcct tcagggagca acaataatga caatgctact
     9841 gccgctcttc attctggttg gttttattgc aggttatttt gttaatgcca tcgcctatca
     9901 cctctcgccg ttggaggata aaacggcgtt aacgtttcgc caggtattgg ttcatttcag
     9961 gcaaaaaaaa tatgcctggc atgatacagt gcccctgata ctttgtgttg ctgctgctat
    10021 cgcctgcgcc ctggcacctt tcacgcccat cgtgactggc gcactctttc tctatttctg
    10081 tttcgtactc acgctcagtg ttattgattt tcgcactcag ctcctgcccg acaaactcac
    10141 cttaccgctg ctctggcttg gcttggtatt taatgcgcag tatggattaa ttgatttaca
    10201 tgatgcggtt tacggcgcgg tagcgggcta tggggtgctg tggtgtgttt actggggcgt
    10261 ctggttagtt tgtcacaaag agggattggg ctacggtgat ttcaagctac tggccgctgc
    10321 aggcgcatgg tgtggctggc aaacgttgcc aatgatactg ctgattgcct cgctgggtgg
    10381 cattggttac gccatcgttt cacaacttct gcaacgccgg actataacca ctatcgcatt
    10441 cggcccgtgg cttgcgctcg gcagcatgat aaacctgggg tatctggcct ggatctctta
    10501 ttaaccggga gggttctccc tcccgacacg gctcaacctt cttcgcggat ctgtgcttgc
    10561 agataatttt gcaggcccat cttctgaatc agatcaagtt ccgtttccag ccagtcgata
    10621 tggccttctt catcacgcaa aatttctatc atcatatcgc ggctgacgta atcatgaacg
    10681 ctatcggcat aaccaattgc ctcacgcaaa ttcttcgcgc catccagctc aagtgccaga
    10741 tcagaacgca gcatttcctc aacatcttca ccaatgttca gtttgcccag gtcctgtaag
    10801 tttggaagac cttccagaaa aagaatgcgc tcaatataac gatcggcgtg tttcatctca
    10861 tcaatggatt catgatactc cacatcattg agacgtttga gaccccagtt tttaaacatt
    10921 cgggcatgga gaaagtactg attgattgcg acaagctcat ttcccaacag tttgttgaga
    10981 taatttataa ctttagtatc acctttcatt ttttgactcc ttcgcttcca ctctttgaag
    11041 agtagaacgg cttacgagta agtcaaaaaa cacactccgt ttatgcggac tccttaaact
    11101 ccggcagctg cattaattca tcctccatca cttcacgcgc ggcccggaca catttaccgc
    11161 actgattgcc gaccggaata aattttttta attgctggaa cgagtgaggg gaaaactggc
    11221 gcacagcctg acgaattttt ttatcgctga taccattaca aagacaaacg tacatagaga
    11281 ctcccgtata ctttcttcaa aaataaatga aaatagttct tatttcaatt acggaaagac
    11341 tcttttttaa gcaaagaata gaaatatgaa taaaaataat gggctaccaa aagtagccca
    11401 ttgacaaaaa atgcggcgat actggaaggt atcgccaaca catttattgc ttagtaaacg
    11461 gcgcgaagat ttcgctaaat gcgtacttcg gtgcctgttc tttagtcagg ccgtggaatt
    11521 ccggagacag gttagtgccg cccggcaggt cgcgcgcgat tgaccagata ccaaccatac
    11581 cgagattacg cttctgcgca tcctgcatga ccagacgagc atcagagaga tagaacacct
    11641 cgccctgaac gtcgttcacg ccaaccatcg gcgtggtacc catcatagcg tcaatttctg
    11701 catcgctctt attgggatgg aggcctttca attgtgaatg caggttggca atcgcagacg
    11761 ttgcacactt accgtgaatg ttctggcctt cggtatttgc agactgacaa atcgcgttac
    11821 cgtagtccat tgtcatcacg ttcacacccg ccagctcaac acctttcgct ttggcatcgc
    11881 tcaggacatt catcccttcc ggcgtcaggc cagtcggcag aattggcaag gtgtaccaga
    11941 tagcaatatc tttgccttct gacttccatt tatcctgcac tttcttcaca gcaaggttac
    12001 gacgttcaat agatgcctga tccgcaaccc aggtgccttc gatatcgaag tccaggactt
    12061 tgaggttcag gttatcaacg atgtcataat aatgctgcat cagatcgtct acgttcttac
    12121 aggaagcagc cagcggagcg ttgttagcac caccgataga cagcatcaca tcgccgccag
    12181 cctcacgcag agctttgatt ttgctgtact gagcgtaatt ctgcataccg taagcggtac
    12241 cccatgtcgg cagacaggtg ttcgcatctt tactcaccac aaacgccagc gtgaagtggt
    12301 tgacgttatg attcttagcc agcgcagcca gatccgggat cgtattcagc gtaaagtcga
    12361 catacggtgc ataaacgtgt ttcggccacg ctttcttcgg cgtacctacg cgctctttgg
    12421 ttccggtcca gtcaacaaaa acacgccacg ggttgctgtc agaaggagaa actttctgca
    12481 ctttactctg agaaatgtag ttcacaccgt taaagcgaat cagcgtatcg ctggcataaa
    12541 gcgtttctgg attaaactgc ggcgcattat tcagctcttc gttgctatag ctctgagcct
    12601 tacctaacgg cttccacggg cggctattgc taccggtggc gttttggttc gccaccagag
    12661 cagggttgtc actttgcgtc cagaacagcg cttcataagc ctgcccatca acaacaacgc
    12721 gatcaccttt cacgtacaca gtggatgcgg accatgcttt cgccggttcg tatttcttcc
    12781 acgggttatc gccgcccggg acaaagcccc atgcgtcttg atcgacagaa gttttataat
    12841 gtgcatcgtt ataatctacg atgctgtccg cgctgtacgc tttgctggcc tggaaaccat
    12901 ccgcaacaat gacgccgccg ttatcaattt cacaggtagt cgggttaccg tactgactca
    12961 attccgcagc ggtagctgta cgctcgagac gccatgggtt attggagttt tcagcgctgg
    13021 taccccgtgg gcaatcttta gacccaaccc accaggcgtt cttgtaaaca ttaccattga
    13081 aaataacatg gtaaatttcg ctaccttcct ggccgctcca cgcttgcaat gagtaatcgt
    13141 taacgctatc cgctggtgtt gatggctcgc tgttatccgg agttggggtc accggtgttt
    13201 ccggagttgg atcaaccgga gtcacagcac cgccattatt atccggctta acggaacagg
    13261 agccagggtt accatactgg ctgatttctg ttgccgttgc cgcgcgaaca taacgccatg
    13321 ggttactggc atcgttttct ttcgcatcgc ctgggcaatt tgccgcgcct acccaccagg
    13381 cgttcttata aatgccgccg ttatagataa cgtaccatgt agaagaacct tcctgacctt
    13441 tccaggctac tacagcatag ttgtcgtttg acttatcagc tggggctggc tgaacatcag
    13501 gagccggttt aacgtccggt gccggtttca catccggtga aggctgtggt gctgaagtac
    13561 aggactgtgg attactggtt tctgagattt ccgttgccgt agcggcacga acataacgcc
    13621 atgggttgct ggcatcattg cttttcgcat cacccggaca gttagaagag gctacccacc
    13681 aggcattttt atataccgca ccattaaaga cgacatacca ggtctgaccg ccctgctgtt
    13741 tattccaggc aactacagaa gaattagacg gaacagtgcc ctgtgctggt gtagccgaac
    13801 cgccattagc cggcgtattg gatgcaggcg tatttgaatt tgaagaagat gagctgccgc
    13861 tcttttcgca ggaaagtgta ttgccaaact gactaatttc agcagctgtt gcggtacgct
    13921 ttaaacgcca cgggttagtt gcatcatttg ctttcgcttt tcccgggcaa tttgtagaag
    13981 aaacccacca ggcattttca taaattttgc catcgaaaat aacctgatat ttattaccac
    14041 cttgttggtt attccatgct tccattgcca atgctggcag agcggaacac accagcccca
    14101 taccaatcat agatttagta aatatattta
//
LOCUS       DAPOAV010000098        13329 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.098, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000098 DAPOAV010000000
VERSION     DAPOAV010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13329
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.098"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            12..842
                     /locus_tag="RN951_003655"
     CDS             12..842
                     /locus_tag="RN951_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313311.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2686 family protein"
                     /protein_id="HDX2528599.1"
                     /translation="MSMPLSNTLQSQIITDNHFLHHPKVDSELTRKYERARLDTENIY
                     LLPLARGNNHNYDGKSVVEIRKLDISKESWPFNYVTEACRESDGITTTGRMLYRNLKI
                     TSALDEIYGGICKKAHAATELAEGLRLNLFMKSPFDPVEDYTVHEITLGPGCNVPGYA
                     GTTIGYISTLPVSQAKRWTNEQPRIDIYIDQIITVSGVANSSGFALAALLNANIEMGN
                     DPIIGIEAYSGTAEIHAKMGYKVIPGDEDAPLKRMTLQPSSLPELFELKNGEWNYIGK
                     "
     gene            complement(983..1756)
                     /gene="uxuR"
                     /locus_tag="RN951_003656"
     CDS             complement(983..1756)
                     /gene="uxuR"
                     /locus_tag="RN951_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Uxu operon transcriptional regulator"
                     /protein_id="HDX2528600.1"
                     /translation="MKSATSAQRPYQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLD
                     VTRTVVREALIMLEIKGLVEVRRGAGIYVLDSSGSHNTDSSDANVCNDAGPFELLQAR
                     QLLESNIAEFAALQATREDIVKMRQALQLEERELASSAPGSSESGDMQFHLAIAEATH
                     NSMLVELFRQSWQWRENNPMWIQLHSHLDDSLYRKEWLGDHKQILAALIKKDTRAAKL
                     AMWQHLENVKQRLLEFSNVDDIYFDGYLFDSWPLDKVDA"
     gene            complement(1971..3431)
                     /locus_tag="RN951_003657"
     CDS             complement(1971..3431)
                     /locus_tag="RN951_003657"
                     /EC_number="1.1.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructuronate reductase"
                     /protein_id="HDX2528601.1"
                     /translation="MTTIVDSNLPVARPSWDHSRLESRIVHLGCGAFHRAHQALYTHH
                     LLESTDSDWGICEVNLMPGNDRVLIENLKKQQLLYTVAEKGAESTELKIIGSMKEALH
                     PEIDGCEGILNAMARPQTAIVSLTVTEKGYCADAASGQLDLNNPLIKHDLENPTAPKS
                     AIGYIVEALRLRREKGLKAFTVMSCDNVRENGHVAKVAVLGLAQARDPQLAAWIEENV
                     TFPCTMVDRIVPAATPETLQEIADQLGVYDPCAIACEPFRQWVIEDNFVNGRPDWDKV
                     GAQFVADVVPFEMMKLRMLNGSHSFLAYLGYLGGYETIADTMTNPDYRKAAFALMMQE
                     QAPTLSMPEGTDLNAYATLLIERFSNPSLRHRTWQIAMDGSQKLPQRLLDPVRLHLQN
                     GGSWRHLALGVAGWMRYTQGVDEQGNAIDVVDPMLAEFQKINAQYQGADRVKALLGLS
                     GIFADDLPQNADFVGAVTAAYQQLCERGARECVAAL"
     gene            complement(3512..4696)
                     /gene="uxuA"
                     /locus_tag="RN951_003658"
     CDS             complement(3512..4696)
                     /gene="uxuA"
                     /locus_tag="RN951_003658"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709912.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HDX2528602.1"
                     /translation="MEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEE
                     ILKRKAIVEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCY
                     NFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAE
                     RFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKA
                     IIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYG
                     VRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEE
                     HRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFF
                     SR"
     gene            5036..6379
                     /gene="gntP"
                     /locus_tag="RN951_003659"
     CDS             5036..6379
                     /gene="gntP"
                     /locus_tag="RN951_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate permease GntP"
                     /protein_id="HDX2528603.1"
                     /translation="MHVLNILWVVFGIGLMLVLNLKFKINSMVALLVAALSVGMLAGM
                     DLMSLLHTMKAGFGNTLGELAIIVVFGAVIGKLMVDSGAAHQIAHTLLARLGLRYVQL
                     SVIIIGLIFGLAMFYEVAFIMLAPLVIVIAAEAKIPFLKLAIPAVAAATTAHSLFPPQ
                     PGPVALVNAYGADMGMVYIYGVLVTIPSVICAGLILPKFLGNLERPTPSFLKADQPVD
                     MNNLPSFGVSILVPLIPAIIMISTTIANIWLVKDTPAWEVVNFIGSSPIAMFIAMVVA
                     FVLFGTARGHDMQWVMNAFESAVKSIAMVILIIGAGGVLKQTIIDTGIGDTIGMLMSH
                     GNISPYIMAWLITVLIRLATGQGVVSAMTAAGIISAAILDPATGQLVGVNPALLVLAT
                     AAGSNTLTHINDASFWLFKGYFDLSVKDTLKTWGLLELVNSVVGLIIVLIISMVA"
     gene            complement(6552..7454)
                     /gene="fimH"
                     /locus_tag="RN951_003660"
     CDS             complement(6552..7454)
                     /gene="fimH"
                     /locus_tag="RN951_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria D-mannose specific adhesin FimH"
                     /protein_id="HDX2528604.1"
                     /translation="MKRVINLFAVLLMGWSVNAWSFACKTANGTAIPIGGGSANVYVN
                     LAPAVNVGQNLVVDLSTQIFCHNDYPETITDYVTLQRGSAYGGVLSNFSGTVKYSGSS
                     YPFPTTSETPRVVYNSRTDKPWPVALYLTPVSSAGGVVIKAGSLIAVLILRQTNNYNS
                     DDFQFVWNIYANNDVVVPTGGCDVSARDVTVTLPDYPGSVPIPLTVYCAKSQNLGYYL
                     SGTTADAGNSIFTNTASFSPAQGVGVQLTRNGTIIPANNTVSLGAVGTSAVSLGLTAN
                     YARTGGQVTAGNVQSIIGVTFVYQ"
     gene            complement(7474..7977)
                     /gene="fimG"
                     /locus_tag="RN951_003661"
     CDS             complement(7474..7977)
                     /gene="fimG"
                     /locus_tag="RN951_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria minor subunit FimG"
                     /protein_id="HDX2528605.1"
                     /translation="MKWCKRGYVLAAILALASATIQAADVTITVNGKVVAKPCTVSTT
                     NATVDLGDLYSFSLMSAGAASAWHDVALELTNCPVGTSRVTASFSGAADSTGYYKNQG
                     TAQNIQLELQDDSGNTLNSGATKTVQVDDSSQSTHFPLQVRALTVNGGATQGTIQAVI
                     SITYTYS"
     gene            complement(7990..8520)
                     /gene="fimF"
                     /locus_tag="RN951_003662"
     CDS             complement(7990..8520)
                     /gene="fimF"
                     /locus_tag="RN951_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria minor subunit FimF"
                     /protein_id="HDX2528606.1"
                     /translation="MRNKPFYLLCAFLWLAVSHALAADSTITIRGYVRDNGCSVAAES
                     TNFTVDLMENAAKQFNNIGATTPVVPFRILLSPCGNAVSAVKVGFTGVADSHNANLLA
                     LENTVSAAAGLGIQLLNEQQNQIPLNAPSSAISWTTLTPGKPNTLNFYARLMATQVPV
                     TAGHINATATFTLEYQ"
     gene            complement(8530..11166)
                     /gene="fimD"
                     /locus_tag="RN951_003663"
     CDS             complement(8530..11166)
                     /gene="fimD"
                     /locus_tag="RN951_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher FimD"
                     /protein_id="HDX2528607.1"
                     /translation="MSYLNLRLYQRNTQCLHIRKHRLAGFFVRLFVACAFAAQAPLSS
                     AELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSE
                     QGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHDATAHLDVGQQRLNLTI
                     PQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIG
                     AWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGI
                     NFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTIND
                     IYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEK
                     PRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPD
                     DSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGV
                     IQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTLTLYLSGSHQTYWGTSNVDEQFQAGL
                     NTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMS
                     HDLNGRMTNLVGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANI
                     GYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTD
                     WRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKL
                     LMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCV
                     ANYQLPPESQQQLLTQLSAECR"
     gene            complement(11233..11958)
                     /gene="fimC"
                     /locus_tag="RN951_003664"
     CDS             complement(11233..11958)
                     /gene="fimC"
                     /locus_tag="RN951_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418736.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria chaperone FimC"
                     /protein_id="HDX2528608.1"
                     /translation="MSNKNVNVRKSQEITFCLLAGILMFMAMMVAGRAEAGVALGATR
                     VIYPAGQKQVQLAVTNNDENSTYLIQSWVENADGVKDGRFIVTPPLFAMKGKKENTLR
                     ILDATNNQLPQDRESLFWMNVKAIPSMDKSKLTENTLQLAIISRIKLYYRPAKLALPP
                     DQAAEKLRFRRSANSLTLINPTPYYLTVTELNAGTRVLENALVPPMGESTVKLPSDAG
                     SNITYRTINDYGALTPKMTGVME"
     gene            complement(11995..12534)
                     /locus_tag="RN951_003665"
     CDS             complement(11995..12534)
                     /locus_tag="RN951_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418735.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDX2528609.1"
                     /translation="MKRKRLFLLASLLPMFALAGNKWNTTLPGGNMQFQGVIIAETCR
                     IEAGDKQMTVNMGQISSNRFHAVGEDSAPVPFVIHLRECSTVVSERVGVAFHGVADGK
                     NPDVLSVGEGPGIATNIGVALFDDEGNLVPINRPPANWKRLYSGSTSLHFIAKYRATG
                     RRVTGGIANAQAWFSLTYQ"
     gene            complement(12599..13153)
                     /gene="fimA"
                     /locus_tag="RN951_003666"
     CDS             complement(12599..13153)
                     /gene="fimA"
                     /locus_tag="RN951_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial major subunit FimA"
                     /protein_id="HDX2528610.1"
                     /translation="MKIKTLAIVVLSALSLSSTAALAETTPTTVNGGTVHFKGEVVNA
                     ACAVDAGSVDQTVQLGQVRTASLKQTGATSSAVGFNIQLNDCDTSVATKAAVAFLGTA
                     IDSAHPKVLALQSSAAGSATNVGVQILDRTGAELTLDGATFSVQTTLNNGTNTIPFQA
                     RYYAIGEATPGAANADATFKVQYQ"
BASE COUNT         3231 a         3465 c         3212 g         3421 t
ORIGIN      
        1 aggtaactat tatgtctatg ccattaagca atacccttca gagccaaatt attacagata
       61 atcacttcct tcatcatcca aaagtcgaca gtgagttaac acgtaaatat gaacgtgcac
      121 gcctggatac ggaaaatatc tatcttctgc ctcttgctcg tggcaataac cataattacg
      181 atggaaaaag cgttgtcgaa attagaaaac ttgatattag taaagagtcc tggccattta
      241 attatgtgac agaagcatgc agagaatccg atggtattac aacaacagga cgtatgctct
      301 atcgaaactt gaaaatcacc tcagctttag acgaaatata tggtggcata tgtaaaaagg
      361 cgcatgctgc tacagaatta gcagaaggtt tacggctaaa tttatttatg aagagccctt
      421 tcgatcctgt tgaggactat acagttcatg aaataacatt aggccctggt tgcaatgttc
      481 caggttacgc cggaaccacg ataggatata tttcaaccct tccagtttct caggcaaaaa
      541 gatggaccaa tgagcagcca agaattgata tctatattga tcagataata actgtctcag
      601 gggtagcaaa ttcttccgga ttcgcccttg ccgcattact taatgctaat attgagatgg
      661 gaaatgaccc aatcattggt atagaagcct attctggtac cgcggagatc catgcaaaaa
      721 tgggatataa agttatcccc ggtgatgaag atgcgccact caaacgcatg actctgcaac
      781 cgtcatctct tccagaactg tttgaattaa aaaatggtga atggaattat attggtaaat
      841 agccactgag aagaatgagt actaatattc aggttataca gatatttaaa caataccctg
      901 caatttataa agcaatactc attgcgactt cttaatttaa gaaagcgcaa ggaacgttta
      961 cccttgcgct tattataata agtcaggcgt cgactttatc cagcggccat gaatcaaaca
     1021 gatagccgtc aaaataaata tcgtcaacgt tcgagaattc cagcagacgt tgcttaacgt
     1081 tttccagatg ctgccacatt gccagcttcg ccgctcgggt atcttttttg attaacgcgg
     1141 cgaggatctg tttgtgatcg cccaaccact ctttgcgata caggctgtca tccagatggc
     1201 tgtgcaactg gatccacatt ggattgtttt cccgccactg ccaggactga cggaataact
     1261 ccaccagcat gctgttatgc gttgcttcgg caatggcgag atggaactgc atatcaccgc
     1321 tttcgctgct acccggcgcg ctggaagcca gttcacgctc ttccagttgc aatgcctgac
     1381 gcattttgac gatatcttcg cgggtagcct gcaaagcggc aaattccgcg atgttacttt
     1441 ccagtaactg acgcgcctgt aacagctcaa aaggacccgc atcattacag acgttggcat
     1501 ccgaactgtc tgtgttgtgg ctgcctgagc tatcaagaac atagataccg gcaccccggc
     1561 gcacttccac cagccctttg atctccagca tgatcagcgc ttcacgtacc accgtccgcg
     1621 tgacatcaag catttctgca atttcacgct ccggcggcag ccgttcgcca ggattgtacg
     1681 gcgtctttat gatcagatcg cggatcatcg ccccgacttc ctggtaaggt ctttgcgcag
     1741 aggtggcaga tttcatggtg ttgtgtccgt taggtgcggt taatcaaatt tttgccggat
     1801 gcggcgtgaa cgccttatcc ggcctacaac gggcaatttt acggcccctg ttaatctcaa
     1861 actataccat tagcactgga agttggcacg tacaggtggg caaaaaaacg aaaactggtc
     1921 aaccaaatat cagtttgatt gaccagtaag tctgtagggt aatcagttag ttacagcgca
     1981 gccacacact cgcgcgcacc gcgttcgcac agctgctgat atgccgccgt caccgcgcca
     2041 acaaagtcgg cattctgcgg cagatcatcg gcaaaaatac cgctcaggcc tagcagcgct
     2101 ttcacgcggt ctgcgccctg atactgcgcg ttaatcttct ggaactcggc cagcatcggg
     2161 tcgaccacgt caatggcatt accctgctca tccacgccct gggtgtaacg catccagcca
     2221 gccacgccca gcgccaggtg acgccagctg ccgccgtttt gcaggtgcag acgcaccggg
     2281 tccagcagac gctgcggtaa cttctggctg ccgtccatcg caatctgcca ggtacggtga
     2341 cgcagagacg ggttgctgaa acgctcgatc agcagcgtcg cataggcgtt caggtccgta
     2401 ccttccggca tcgacagcgt tggcgcttgt tcctgcatca tcagggcaaa ggccgctttg
     2461 cgataatccg ggttagtcat ggtgtcggca atagtttcat agccgccgag gtaaccgagg
     2521 tacgctagga aagagtggct accgttcagc atacgcagct tcatcatttc gaacggcaca
     2581 acgtctgcaa cgaactgtgc gcccacttta tcccagtccg ggcgaccatt aacgaaatta
     2641 tcttcaatca cccactgacg gaacggttcg caggcaatgg cgcacgggtc gtaaacgccc
     2701 agctggtcag caatttcctg taaggtttct ggcgtcgccg ccggaacgat gcggtcaacc
     2761 atggtgcacg ggaaggtgac gttctcttca atccatgccg ctagctgcgg gtcacgcgcc
     2821 tgagccagcc ccagtaccgc gaccttcgcc acatgaccgt tttcacgcac gttatcgcag
     2881 gacatcaccg taaatgcttt cagccctttt tcacgacgca gacgcaaggc ttcgacgatg
     2941 taaccaatcg cggacttcgg cgcagtcggg ttttccagat cgtgcttgat cagcgggtta
     3001 ttgagatcca gttgaccgct tgccgcatca gcgcagtagc ctttttccgt gaccgtcaga
     3061 gagacaatcg ccgtttgcgg acgcgccatc gcgttgagaa taccttcgca gccgtcgatt
     3121 tccgggtgca gcgcttcttt catcgaaccg ataattttca gctcggtgct ttccgcgcct
     3181 ttttccgcca cggtgtacag cagttgctgt tttttcaggt tttcgatcag cacgcggtcg
     3241 ttgcctggca tcaggttaac ttcgcagata ccccagtcgc tgtcggtgct ttccagcaga
     3301 tgatgggtgt acagcgcctg gtgcgcacgg tgaaacgccc cgcaaccgag atgcacaatg
     3361 cgtgattcca gacgagaatg atcccatgac gggcgggcaa ccggcagatt gctgtcaaca
     3421 atagtagtca tcgtaaactc cagaatccgt cttcagagag tgacggcaag gaagaaggaa
     3481 ccggcacggc gcgcagccat gccggtggat attaacggct aaagaaagcg cgctggatcg
     3541 ccagttcgac accgcgaact tcggccaggc ctttcagacg accaattgcg gagtaacctg
     3601 ggttggtttt cttcttcagg tcgtccagca tctgatgacc gtggtccgga cgcatcggga
     3661 tcaggtcttc tttgccttcc gctttacgac ggtgttcttc ttcaacaatc gctttcacca
     3721 cttcgtacat atcaacgtca ccgttcaggt gcgccgcttc gtggaaggtt ttcgggttat
     3781 cttcacgcat ggtggagcgc agatgggtga agtaaatacg cggaccgaac tgcttgatca
     3841 tatcaaccag atcgttgtca gcacgcacgc cgtaggaacc ggtgcacatg gtgaaaccgt
     3901 tcgccatgct atttacggta tcaaccatcc actgcatatc ttcaatggta gaaacaatgc
     3961 gcggcaggcc gaggattggg cgcggcggat cgtccgggtg aacagccata cgcacgccaa
     4021 cttcttcggc aaccggaata atcgccttca ggaagacggc aaagttttcg cgcagtttgg
     4081 ctttgtcgat atctttgtac agctccaggt gcttacggaa ctggtcgagg gtgtaccctt
     4141 cttccgcgcc cggcagaccg gcaatgatgt tacgggtcag acgcgctttg tcttcgtcgc
     4201 tcatagtggc gaagcgttca gctgcctgag caatttcttc ttcggtgtaa tccgcttccg
     4261 cacctgggcg tttcaggata tgcatttcga atgcagcgaa ttcgatctgg tcgaagcgca
     4321 gagctttgga gccgtctggc agcacgtatt cgaggtcagt acgggtccag tcgagcaccg
     4381 gcatgaagtt gtagcacacg gtgcgaatac cgcactgcgc caggttgcgc agagtctgct
     4441 gatagttagc gatccactgc tcatagttgc cagtgtgggt tttgatatct tcgtgaattg
     4501 gcacgctttc tacgacagac cacaccaggc ctgcatcttc aacgatagcc ttgcgtttga
     4561 ggatctcttc tacggaccat acttcaccgt tcgggatatg gtgcaaagcg gtaaccacgc
     4621 cagtcgcgcc cgcctgacgg acatcagcta aagaaaccgg atcgtttggg ccgtaccagc
     4681 gccaggtctg ttccatgatt tttcctcttt cacatagtgg gttccacagc aaagagacgc
     4741 ggaaccctgg agttgtttag gtatccggat gaacaaccag accgcagccg tggcgttgca
     4801 tcggatgaga tggcgtataa gttctacctt ttggtaagac atgtcaaccc gaattctgaa
     4861 attggttaac cacatcacaa gaatttcact ctcctggttg ttgctgcaaa ttgcagcaaa
     4921 aggtaatcga tggttattga tcagaggatg tgacattcat cgcaacaatg gttgaccaat
     4981 ttacataaca tgtcgcccaa aataacaacg gttcaaccag gtaaggtaaa acgttatgca
     5041 tgtgcttaac attctctggg tggtattcgg cattggtctg atgctggtac tgaatttgaa
     5101 gttcaaaatc aattcaatgg tggccttgtt ggtggcggcg ctgtccgtcg ggatgctggc
     5161 gggcatggat ttgatgtcgc tgctgcacac catgaaagcg ggcttcggca acacgctggg
     5221 ggaactggct atcatcgtgg tgttcggtgc ggtcatcggt aaattgatgg tcgactccgg
     5281 cgcggctcac cagatagcgc atacgctgct ggcacgtctc ggtctgcgtt atgtacagct
     5341 gtcggtgatt atcatcggcc tgattttcgg tctggcgatg ttctatgaag tggcctttat
     5401 catgttagca ccgctggtta ttgttattgc cgccgaagct aaaattccgt tcctgaaact
     5461 ggcgatcccg gcagtagcag ctgccactac cgcacattca ctgttcccac cgcagccggg
     5521 tccggtggcg ctggtgaatg cttatggcgc ggatatgggg atggtttata tctatggcgt
     5581 actggtgacg atcccaagtg tcatctgcgc aggtctgatc ctgccgaagt tcctcggcaa
     5641 tcttgagcgc ccaacgccat cattcctgaa agcagatcaa ccggtagata tgaataatct
     5701 gccctctttc ggcgtttcga ttctggtgcc gttgatcccg gcgatcatta tgatctctac
     5761 caccatcgcc aatatctggc tggtaaaaga tacccctgcg tgggaagtgg ttaactttat
     5821 cggttcctcg ccgattgcaa tgtttattgc gatggtggtt gcattcgtac tctttggcac
     5881 cgcgcgcggg cacgatatgc agtgggtaat gaacgctttt gaaagcgcgg tgaaaagcat
     5941 tgcaatggtg attctgatca tcggtgcagg tggcgtgctg aagcagacca tcatcgacac
     6001 cggcatcggc gacaccatcg gcatgctgat gtcccacggc aatatctcgc cctacatcat
     6061 ggcatggctg atcaccgtac tgattcgtct ggcgacgggt cagggtgtgg tttcagcgat
     6121 gaccgccgcc gggattatca gtgcagcaat ccttgatcca gcaactggtc agctggttgg
     6181 cgtgaatccg gcgctgctgg tactggcgac ggctgcgggt tccaacaccc tcacccacat
     6241 taacgatgcc tcattctggt tgttcaaagg ttactttgac ctgtcagtaa aagacacgtt
     6301 gaaaacctgg ggtctgctgg agctggtcaa ctccgtggtt gggctgatta ttgtgctgat
     6361 tattagcatg gtagcgtaaa agagcacctg agcctgccat tggcaggctc tgttcggatt
     6421 gtcggtaaag tgcgctttgt ttatgccaga tgcgacgctg acgcgtctta tctggcctac
     6481 aaagggctaa cgtgcaggtt ttagcttcag gtaatattgc gtacctgcat tagcaatgcc
     6541 ctgtgatttc tttattgata aacaaaagtc acgccaataa tcgattgcac attccctgca
     6601 gtcacctgcc ctccggtacg tgcgtaattt gccgttaatc ccagacttac cgccgaagtc
     6661 cctactgctc ctaacgatac cgtgttattc gctggaataa tcgtaccgtt gcgcgtcaac
     6721 tgtacgccga cgccctgtgc aggtgaaaac gacgcggtat tggtgaaaat cgagttgccc
     6781 gcatctgcgg ttgtgccgga gaggtaatac cccaggtttt ggcttttcgc acaataaacg
     6841 gtaagaggaa tcggcactga accagggtag tccggcagag taacggtgac atcacgagca
     6901 gaaacatcgc agccgccagt gggcaccacc acatcattat tggcgtaaat attccacaca
     6961 aactggaaat catcgctgtt atagttgttg gtctgtcgca aaataagcac ggcaattaat
     7021 gagccagctt taatcaccac cccgcccgca ctgctcacag gcgtcaaata aagcgccacc
     7081 ggccacggct tatccgttct cgaattataa acaacccgcg gcgtttcact ggtggtcgga
     7141 aatggatagc tactgccact atattttacg gtcccggaaa aattagataa cacgccgcca
     7201 taagccgagc ctcgttgcag tgtgacataa tctgtaatgg tttccgggta atcgttatgg
     7261 caaaagattt gcgtcgaaag atccacgacc aggttttgcc ccacattcac ggcgggcgca
     7321 aggtttacat aaacattggc gctgccaccg ccaataggga tagcggtgcc attggcggtt
     7381 ttacaggcga atgaccaggc atttaccgac cagcccatca gcagtacagc aaacaggtta
     7441 ataactcgtt tcattacaat catctcttcg gcttcagctg taggtatagg tgatgctaat
     7501 cactgcctga atggttccct gagtggctcc gccatttacc gtcaatgctc tgacctgtaa
     7561 cgggaagtgc gttgattgtg aggaatcatc cacctgaact gttttggttg cgccactatt
     7621 caatgtgttg ccactgtcat cctgtagctc taactggatg ttttgcgcgg tcccctggtt
     7681 tttataatat ccggtactgt cggctgcccc gctgaagctg gcagtgaccc tcgacgttcc
     7741 caccggacaa ttagtcaact caagcgcaac atcatgccag gccgatgccg ccccggcaga
     7801 catcagactg aaagaataaa gatcgccgag atctaccgtg gcattggtgg tggaaaccgt
     7861 gcacggtttg gcgacgacct taccgttcac cgtgatggtg acatcggctg cctgtatcgt
     7921 cgcacttgcg agcgccaata ttgccgccaa tacataccca cgtttgcacc atttcatgaa
     7981 catctccagt tactgatatt caagagtgaa ggtagccgtg gcattgatat gccccgcagt
     8041 gacaggcacc tgtgtcgcca ttagccgggc gtaaaaattc agcgtatttg gtttacccgg
     8101 cgtcagggtc gtccacgaaa tcgcggacga tggggcatta aggggtatct gattttgttg
     8161 ctcattcaga agctgtattc ccagtcccgc agccgctgac accgtatttt caagtgcaag
     8221 caggttggca ttgtggctat ctgcaacacc ggtaaaccca acttttacgg cagaaacggc
     8281 attaccacag ggtgacagca aaatacgaaa tggaacgaca ggagtcgtcg cgccaatgtt
     8341 gttaaattgc ttcgccgcgt tttccatcag atcaacagta aaattggttg attcagcggc
     8401 cacactacag ccgttatctc tgacatagcc gcggatagta atcgtgctat ccgcagccaa
     8461 agcgtgactt accgccagcc acaaaaaagc gcacagaaga taaaaaggtt tgtttctcat
     8521 cacgccccct taacgacatt cagctgatag ctgggttaat aactgctgct gactctctgg
     8581 tggcagttga taattggcga cacagtgagc attttcctct tctccccatt tcacctgaac
     8641 ttttcccgct aaaggcattc cgctgaggta aacctgacca ttatccgcaa caatgccgct
     8701 actctggcta ctctctgatg tcaccatcgc cccaaacggc agcggcttat tattgtgggt
     8761 tagcgtcatg agcagtttta tcccaacgcg cgctttaaac tctgctcgca cgatcgcccc
     8821 acgggtggga acaacgttag cgaccgcgtt atctaaatcg acgttatcag ccagggtatt
     8881 ggtatccagc gctactctgt tttcccgata ttcagtggca taaggcagca cggcataacc
     8941 gcgccagtcg gtacgcaccc ccgtctggtt ttcgactttt gcatcttttg cgccaggcgc
     9001 tttaacaagc accaccgtat cgtttaacgg ctgccccagc gttacgccat tggcatgagc
     9061 cagtacccca ccgctgactc cgtaatagag ctgcttaata tcatcgctat ggctgtaacc
     9121 gatgttggca ttgccgtaac caccgcgata attcagcgtg gcgtagcctg tacttccgct
     9181 attaccatca cctcccccgg cgtaaccggt ttgcacgcta tagctgaggt tgttgtcttc
     9241 cagcaacgta ccgtatacac cgaccagatt ggtcatccga ccgttgagat cgtgtgacat
     9301 gctgtaactg gcactggcat gtcgccactg agatttactg tcagaacgca gccagtggct
     9361 gaaaggaata ttgacgttaa gcgctaacat ctgatcccgt cctttttgcc aggcgttttt
     9421 cgtcaggcta tagctgagcg tccagttgat atcttcgaat gcagtattta aaccagcctg
     9481 gaattgctca tcgacattac tcgttcccca ataagtttga tggctaccac tcaaatacag
     9541 tgttaatgtg cgcccgagtt gctgagtaac ggtgagttgt aatttcccgc gtttgttata
     9601 agcgagattg taatagtcgg tgaatttcgg cttaacctga ataacaccat cctgtgtttc
     9661 gatgttgtag ccattcattc gactgtatgt tgtatcagcg aaattaaaat atccgctggt
     9721 cgaataacgg taacccacta actgaatatt cgtgcctgat tcattgagcg atttgttata
     9781 gagaaaacgc accgattgtc cgtcatgctg actgtcatcg ggaagtgtgg aattagcctg
     9841 cgtcatatcc acagacagag cgcccagtgc ccccatgttt ttcccgatac cgaaattaaa
     9901 cgcacgataa cgatccgcca gttgcgttcc accatatatt gtccagccag ccggaaggcc
     9961 gtggagtaat gtactctgga aaaagcgggg tttttcctgc tgcgcatttc cactacggta
    10021 ttctcctgcc gtaatggaat aacgagtatg cccttcacgt tgcaaaagcg ggactgacga
    10081 atagggtacg gtaaagatct gcgtgctgcc gtcagcctct ttaatcgtta cctgcaagtc
    10141 accactatta cctgcggcat agatatcgtt gatggtaaaa ggccccggcg gcaccgtact
    10201 attataaatg tcatacccat tttgtttaat agtgacctgt gcagtaccac gagcaatacc
    10261 gtggatcacc ggggcaaatc ctctttggct atcgggtaac atattgtcat ctgaggccaa
    10321 ttgtgcgccg cgaaagttaa taccatcgaa aatatcgccc tgggtataac catcacccag
    10381 cgtcagccgg gaacgtaacg gaattatgtc tcgctcaagc caggtattga tatgctgcca
    10441 tttatttttg ctacctgatg aactgtcgct actgttataa ctccaggtgg tattgtcgcg
    10501 taaacgccac gcaccaatat ttaacccact ctgtaggttt aaatatgcat aatggctgtt
    10561 acccccaatc cgattctgta cactatttcc gctgaaatta taattgagca atccggcatt
    10621 aataccagga tcccataact caggaggaat ataaccacgc gcgcgattac tcataaatgc
    10681 ctgagggatc gtcaggttga gtcgctgctg accaacatcc agatgcgcag tagcgtcatg
    10741 gatcattgag gttaatggca cgcaggcatc atccgccagc agattcatac cggagacaga
    10801 agccgtattc agccccatac ttgcaagttg cgcgcgtgtc aggcagggaa caatcccttg
    10861 ttcactgtcg cccgtattaa atgtgacatc acgcgttgcc atataaccat tattcaaata
    10921 gatatcgaca cgatacgtcc ctggcggtaa ttcttgccca ttttcaaaac gcgataaatc
    10981 ggccacagcc tggggatcat ccgctaaaaa gcgcggatta aaatagagtt cggcagatga
    11041 caaaggtgcc tgtgcggcaa aagcacaggc gacaaagagc cggacaaaaa aaccagccaa
    11101 acgatgctta cgaatatgca agcattgtgt gtttcgctgg taaagtctta aattcagata
    11161 tgacattatt cctccggttt aaaatcaccc ggcagtcaat tctttttatt caggcgaaaa
    11221 attccccctg cgttattcca ttacgcccgt cattttgggg gtaagtgcgc cataatcatt
    11281 tattgttcgg taagtaatat tgcttcctgc atcagaaggc aatttaaccg tgctttcgcc
    11341 cattggaggc accaatgcat tttcaagaac ccgggttccg gcattcaact ctgttaccgt
    11401 caggtaatag ggtgtcgggt taatcagagt cagagaattc gcgctacgac gaaatcttaa
    11461 tttttctgcg gcctgatcgg gtggcaacgc taatttagcc gggcgatagt acagtttaat
    11521 gcggctgata attgcgagct gtagcgtatt ctcagtcaat tttgatttat ccattgacgg
    11581 aatcgcttta acgttcatcc agaataaact ttcccgatcc tgtggcaatt ggttatttgt
    11641 tgcatcaaga atacgtaagg tattctcttt ttttcccttc atcgcaaaca gaggtggcgt
    11701 cacgataaaa cgaccatcct ttacaccatc ggcattttcc acccatgatt gaattaaata
    11761 ggtgctattt tcatcattat ttgtcacggc aagttgcact tgtttttgcc ctgccggata
    11821 aattacgcgg gtcgcaccta aggccactcc cgcttcagcg cgtccggcaa ccatcattgc
    11881 catgaacatc aggatacctg ccagcaagca gaatgttatt tcctgcgatt tccttacatt
    11941 gacgttttta ttactcactg tcctgttcct gttatcacat tatctgctga acaattactg
    12001 ataggttaaa gagaaccagg cctgggcatt ggcgatgccg ccagtaaccc gacgcccggt
    12061 agcacgatat ttggcgatga aatgtagcga agtagagcct gagtaaagcc gtttccagtt
    12121 tgctggagga cgattaatcg gtacgaggtt tccttcatca tcaaataacg ctacgccaat
    12181 gtttgtggct atccctggcc cctctcccac ggaaagcaca tccggatttt taccatccgc
    12241 gacaccgtga aacgccacac ccacacgttc actcaccacc gtgctacatt cccgtaaatg
    12301 aataacaaaa ggcaccggtg cgctatcttc ccctaccgca tgaaaccggt tactgctgat
    12361 ttgccccata ttgaccgtca tttgtttatc tccggcttca atccggcaag tttccgcaat
    12421 aatgacgccc tgaaattgca tatttccgcc gggcaacgtg gtattccatt tatttccggc
    12481 cagagcaaac attggcagca acgacgctaa cagaaataat ctcttccttt tcatcgttat
    12541 ttttatcgca caagggtggg catccctgcc cgtaatgacg tccctgaacc tgggtaggtt
    12601 attgatactg aaccttgaag gtcgcatccg cattagctgc gccaggggtt gcctcgccga
    12661 ttgcataata acgcgcctgg aacggaatgg tgttggtacc gttattcaag gttgtttgta
    12721 cactaaatgt cgcaccgtcc agcgtcagct cagcacccgt tctgtccagt atctgcacac
    12781 caacatttgt tgcgctaccc gcagctgaac tctgcagagc cagtacttta ggatgagcac
    12841 tgtcaatcgc agtccccaag aaggcaacag cggcttttgt ggcaacactg gtatcgcaat
    12901 cattcagctg aatgttaaaa ccgacagcag agctggttgc tccagtctgc ttcagactag
    12961 cggtacgaac ctggcccaac tgaacggttt gatcaacaga gcctgcatca actgcgcaag
    13021 cggcgttaac aacttcccct ttaaagtgaa cggtcccacc atttaccgtc gtgggtgtag
    13081 tttcagccag agccgctgta gaactcaggg acagagccga cagaacaaca attgccagag
    13141 ttttaatttt catactgctt tcctttcaaa aaactatttc taaatcgaca tgggcagtcg
    13201 ttctgtacac tttgttttgt caacgagttt gactgccaac actgcacagt ttccccccaa
    13261 aagatgaaac atttggggcc attttgactc atagaggaaa gcatcgcgca caaacttttt
    13321 cagtttatt
//
LOCUS       DAPOAV010000099        13328 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.099, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000099 DAPOAV010000000
VERSION     DAPOAV010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13328
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.099"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            99..1598
                     /gene="pitB"
                     /locus_tag="RN951_003667"
     CDS             99..1598
                     /gene="pitB"
                     /locus_tag="RN951_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter PitB"
                     /protein_id="HDX2528611.1"
                     /translation="MLNLFVGLDIYTGLLLLLALAFVLFYEAINGFHDTANAVATVIY
                     TRAMQPQLAVVMAAFFNFFGVLLGGLSVAYAIVHMLPTDLLLNMGSTHGLAMVFSMLL
                     AAIIWNLGTWFFGLPASSSHTLIGAIIGIGLTNALLTGSSVMDALNLREVTKIFSSLI
                     VSPIVGLVIAGGLIFLLRRYWSGTKKRDRIHRIPEDRKKKKGKRKPPFWTRIALIVSA
                     AGVAFSHGANDGQKGIGLVMLVLVGIAPAGFVVNMNASGYEITRTRDAVTNFEHYLQQ
                     HPELPQKLIAMEPPLPAASTDGTQVTEFHCHPANTFDAIARVKTMLPGNMESYEPLSV
                     SQRSQLRRIMLCISDTSAKLAKLPGVSKEDQNLLKKLRSDMLSTIEYAPVWIIMAVAL
                     ALGIGTMIGWRRVAMTIGEKIGKRGMTYAQGMAAQMTAAVSIGLASYIGMPVSTTHVL
                     SSAVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAIFLSGGLYWIALQLI"
     gene            complement(1647..2339)
                     /locus_tag="RN951_003668"
                     /pseudo
     CDS             complement(1647..2339)
                     /locus_tag="RN951_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417460.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
     gene            2513..3226
                     /locus_tag="RN951_003669"
     CDS             2513..3226
                     /locus_tag="RN951_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HDX2528612.1"
                     /translation="MNQRNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPT
                     EHIYLGQSSGRIGEWISQLPVIGAPCGRYLRSKAAHVHEKPSTPPGNITALVIYLLSC
                     WRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELK
                     LYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAALQEKIAVTPQLTFNGAKILELDGR
                     HPADEILQASLRAIHAALS"
     gene            3258..4016
                     /locus_tag="RN951_003670"
     CDS             3258..4016
                     /locus_tag="RN951_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528613.1"
                     /translation="MDALQTQTVNSTTAPQPNYIPGLIAVVGCDGTGKSTLTTDLVKS
                     LQQHWQTERRYLGLLSGEDGDKIKRLPLVGVWLERRLAAKSSKTQSMKTKSPALWAAV
                     IMYCFSLRRMANLRKVQRLAQSGVLVVSDRFPQAEISGFYYDGPGIGVERATGKISMF
                     LAQRERRLYQQMAQYRPELIIRLGIDIETAISRKPDHDYAELQDKIGVMSKIGYNGTK
                     ILEIDSRAPYSEVLEQAQKAVSLVAIVSDRRSLT"
     gene            4062..5411
                     /locus_tag="RN951_003671"
     CDS             4062..5411
                     /locus_tag="RN951_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HDX2528614.1"
                     /translation="MAGFNIKHWFADGAFRTIIRNSAWLGSSNVVSALLGLLALSCAG
                     KGMTPAMFGVLVIVQSYAKSISDFIKFQTWQLVVQYGTPALTNNNPQQFRNVVSFSFS
                     LDIVSGAVAIVGGIALLPFLSHSLGLDDQSFWLAALYCTLIPSMASSTPTGILRAVDR
                     FDLIAVQQATKPFLRAAGSVVAWYFDFGFAGFVIAWYVSNLVGGTMYWWFAARELRRR
                     NIHNAFKLNLFESARHIKGAWSFVWSTNIAHSIWSARNSCSTVLVGIVLGPAAAGLFK
                     IAMTFFDAAGTPAGLLGKSFYPEVMRLDPRTTRPWLLGVKSGLLAGGIGILVALAVFI
                     VGKPLISLVFGVKYLEAYDLIQVMLGAIVISMLGFPQESLLLMAGKQRAFLVAQTIAS
                     IGYIVLLFMFCHLFGVLGAAFACFGGQCLDVALSLIPTLKAFFQRHSLLYNAAGEKS"
     gene            5411..6235
                     /locus_tag="RN951_003672"
     CDS             5411..6235
                     /locus_tag="RN951_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528615.1"
                     /translation="MMRKYFPLEASERLFVAIEEDDVVDAQVSLPPTIALSCTTEIIH
                     DNYALCLQFWLNGVDRQELLRLVRKQAKGDELTADERKQFKYMRARYKHLRFAQRLYL
                     KKHQAGFLFGKTTVFLGRFQDGFRNGKKNIVSYYGNLLRIYLSSPVWSLVNYSLRHSQ
                     LESVSGFIAYRQKQMHTLKEIIAKPRLTGREFHDVRKIISQQVSYYDTLRSLDPENKE
                     ALQISRFLAAINGLMGDKHDDMVADDMENRQSYDAPLALDSDIRQRLELLISRFPL"
     gene            6247..6807
                     /locus_tag="RN951_003673"
     CDS             6247..6807
                     /locus_tag="RN951_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708799.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtfJ family protein"
                     /protein_id="HDX2528616.1"
                     /translation="MSSRLIIALIIMLLAPGVQAHNFVTGKTVTPVYIQEGGELLLNS
                     DDEIHYQKWKSTQLAGKVRIIQYIAGRKSAKKKNSLLIKAVEAANFPQDRFQPTTIVN
                     TDDAIFGTGYFVVGKIEKNKRRYPWAQFIIDGNGQGRVAWRLPEQSSTILVLNKAGQI
                     QWAKDGSLTPEEVDHVIALAQKLINE"
     gene            6838..7908
                     /gene="lptF"
                     /locus_tag="RN951_003674"
     CDS             6838..7908
                     /gene="lptF"
                     /locus_tag="RN951_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptF"
                     /protein_id="HDX2528617.1"
                     /translation="MKLVEHYIMRGTRRLVLIIVGFLIFIFASYSAQRYLTEAANGTL
                     ALDVVLDIVFYKVLIALEMLLLVGLYVSVGVTLGQMYTDSEITAISAAGGSPGRLYKA
                     VLYLAIPLSIFVTLLSMYGRPWAYAQIYQLEQQSQSELDVRQLRAKKFNTNDNGRMIL
                     SQTVDQDNNRLTDALIYTSTANRTRIFRARSVDVVDPSPEKPTVMLHNGTAYLLDHQG
                     RDDNEQIYRNLQLHLNPLDQSPNVKRKAKSVTELARSAFPADHAELQWRQSRGLTALL
                     MALLAISLSRVKPRQGRFSTLLPLTLLFIAIFYGGDVCRTLVANGAIPLIPGLWLVPG
                     LMLMGLLMLVARDFSLLQKFSR"
     gene            7905..8984
                     /gene="lptG"
                     /locus_tag="RN951_003675"
     CDS             7905..8984
                     /gene="lptG"
                     /locus_tag="RN951_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HDX2528618.1"
                     /translation="MNVFSRYLIRHLFLGFAAAAGLLLPLFTTFNLINELDDVSPGGY
                     RWTQAVLVVLMTLPRTLVELSPFIALLGGIVGLGQLSKNSELTAIRSMGFSIFRIALV
                     ALVAGILWTVSLGAIDEWVASPLQQQALQIKSTATALGEDDDITGNMLWARRGNEFVT
                     VKSLNEQGQPVGVEIFHYRDDLSLESYIYARSATIKDDKTWILHGVNHKKWLNGKETL
                     EILDNLAWQSTFTSMNLEELSMPGNSFSVRQLNHYINYLQETGQPSSEYRLALWEKLG
                     HPILTLAMILLAVPFTFSAPRSPGMGSRLAVGVIVGLLTWISYQIMVNLGLLFALSAP
                     VAALGLPMAFVLAALILVYLFDRQH"
     gene            complement(9019..10191)
                     /locus_tag="RN951_003676"
     CDS             complement(9019..10191)
                     /locus_tag="RN951_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDX2528619.1"
                     /translation="MGLYDKYARLAGERLQFSDNGLTPFGTCIDEVYSATEGRIGNKK
                     VILAGTNNYLGLTFNHDAISEGQAALAAQGTGTTGSRMANGSYAPHLALEKEIAEFFK
                     RPTAIVFSTGYTANLGVISALADHNAVVLLDADSHASIYDACSLGGAEIIRFRHNDAK
                     DLERRMVRLGERAKEAIIIVEGIYSMLGDVAPLAEIVDIKRRLGGYLIVDEAHSFGVL
                     GATGRGLAEAVGVEDDVDIIVGTFSKSLASIGGFAVGSEAMEVLRYGSRPYIFTASPS
                     PSCIATVRSSLRTIATQPELRQKLMDNANHLYDGLQKLGYELSSHISPVVPVIIGSKE
                     EGLRIWRELISLGVYVNLILPPAAPAGITLLRCSVNAAHSREQIDAIIQAFATLKQ"
     gene            complement(10191..10439)
                     /locus_tag="RN951_003677"
     CDS             complement(10191..10439)
                     /locus_tag="RN951_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDX2528620.1"
                     /translation="MVNREIVMDYILSCLQDLVENGVEIKPDSDLVNDLGLESIKVMD
                     LLMMLEDRFDISIPINILLDVKTPAQLMETLLPWLENK"
     gene            complement(10471..11385)
                     /locus_tag="RN951_003678"
     CDS             complement(10471..11385)
                     /locus_tag="RN951_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001481799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HDX2528621.1"
                     /translation="MNQTVAVTGATGFIGKYIIDNLLARGFHVRALTRTARAHVNDNL
                     TWVRGSLEDTHSLSKLVAGASAVVHCAGQVRGHKEEIFTRCNVDGSLRLMQAAKESGF
                     CQRFLFISSLAARHPELSWYANSKHVAEQRLTAMADEITLGVFRPTAVYGPGDKELKP
                     LFDWMLRGLLPRLGAPDTQLSFLHVTDFAQAVGQWLSAETVQTQTYELCDGVPGGYDW
                     QHVRQLAADARCGSVRMVGIPLPVLTCLADISTALSRLAGKEPMLTRSKIRELTHADW
                     SASNNRISEDINWFPGISLEQALRNGLF"
     gene            complement(11382..13112)
                     /locus_tag="RN951_003679"
     CDS             complement(11382..13112)
                     /locus_tag="RN951_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acyl-AMP ligase"
                     /protein_id="HDX2528622.1"
                     /translation="MVYMSNKIFTHSLPMRYADFPTLVDALDYAALSSAGMNFYDRRC
                     QLEDQLEYQTLKTRAEAGAKRLLSLNLKKGERVALIAETSSGFVEAFFACQYAGLVAV
                     PLAIPMGVGQRDSWSAKLQGLLASCQPAAIITGDEWLPLVNAATHNNPELHVLSHAWF
                     KALPEADVALQRPVPNDIAYLQYTSGSTRFPRGVIITHREVMANLRAISHDGIKLRPG
                     DRCVSWLPFYHDMGLVGFLLTPVATQLSVDYLRTQDFAMRPLQWLKLISKNRGTVSVA
                     PPFGYELCQRRVNEKDLAELDLSCWRVAGIGAEPISAEQLHQFAECFRQVNFDDKTFM
                     PCYGLAENALAVSFSDEGSGVVVNEVDRDILEYQGKAVAPGAETRAVSTFVNCGKALP
                     EHGIEIRNEAGMPVAERVVGHICISGPSLMSGYFGDQASQDEIAATGWLDTGDLGYLL
                     DGYLYVTGRIKDLIIIRGRNIWPQDIEYIAEQEPEIHSGDAIAFVTAQEKIILQIQCR
                     ISDEERRGQLIHALAARIQSEFGVTAAIDLLPPHSIPRTSSGKPARAEAKKRYQKAYA
                     ASLHVQESLA"
BASE COUNT         3219 a         3266 c         3451 g         3392 t
ORIGIN      
        1 tctttttatc gttaaaaaat gatatttcac tttgcccatg ccgttaaagt cactgataat
       61 gcgtccgttc gtaaattcaa aatggcgtaa tctaatatat gctaaattta tttgttggcc
      121 ttgatatata cacagggctt ttgttattgc ttgctctggc atttgtgttg ttctacgaag
      181 caatcaatgg ttttcatgac acggcgaatg cggtggcaac cgttatttat actcgtgcca
      241 tgcaaccaca acttgctgtg gtgatggcgg cattttttaa cttttttggc gtgttattgg
      301 gcggacttag cgttgcctat gccattgtcc atatgttgcc aaccgatttg ttgctgaata
      361 tggggtcaac ccacggcctg gcgatggtct tttccatgct gctggcggcg attatctgga
      421 acctgggaac gtggttcttc ggtttaccgg cctccagttc gcacaccttg attggtgcga
      481 ttatcggcat cggtttaacc aacgcgctgt taaccggctc atcggtgatg gatgcgttaa
      541 acctgcgtga agtgaccaaa attttctcct cgctgattgt ttcccctatc gtcggcctgg
      601 tcattgcggg aggcctgata ttcctgctgc gacgctactg gagcgggacg aaaaagcgtg
      661 accgtattca ccgcattccg gaagatcgca aaaagaaaaa aggcaaacgt aaaccgccat
      721 tctggacgcg tattgcgctg attgtttccg ctgcgggcgt ggcgttttcg cacggcgcga
      781 acgacggaca aaaagggatc ggcctggtga tgctggtact ggtggggatt gcccctgctg
      841 gcttcgtcgt caatatgaac gcgtccggct atgaaattac ccgtacccgc gatgccgtca
      901 ccaacttcga acactacctg caacagcatc ctgaactgcc gcagaagttg attgcgatgg
      961 aacctccatt gcctgcagca tcgactgatg gcacgcaagt aacagagttt cactgtcatc
     1021 cggcaaatac ctttgatgcg attgcgcgcg ttaaaacgat gctgccaggc aatatggaaa
     1081 gttacgagcc gttaagcgtg agtcagcgca gccagctgcg ccgcattatg ctgtgcatct
     1141 ctgatacctc cgcgaagctg gcgaaactgc caggcgtcag taaagaagac cagaacctgc
     1201 tgaaaaaact gcgcagcgat atgttaagca ccattgagta cgctccggtg tggatcatca
     1261 tggcggtagc actggcgctc ggcattggca ccatgattgg ctggcgtcgt gtagcgatga
     1321 ccatcggtga gaagattggt aagcgcggca tgacgtatgc gcaaggcatg gcggcacaaa
     1381 tgacggcggc agtgtctatc ggccttgcca gttatattgg gatgcctgtc tccacaacac
     1441 acgtcctctc gtctgcggta gcagggacga tggtggtgga cggcggtggg ttacagcgta
     1501 aaacggtaac cagcatcctg atggcgtggg tgtttacttt accggcggca atttttcttt
     1561 ctggtgggct gtactggata gcattgcagt tgatttaacc ttcctgaaaa tgcccggtcc
     1621 tggcgatcgg gcatttccat ttttgactag tgataaccac gcgcggtcat aaaatccgta
     1681 atcgcttttt ctgcatcaac caacacctgt tccagtggcc gattggcatc gatatcaacc
     1741 agttgtgcac caccaaaggt taactgtggc gttatggcaa tcttcctcgc cagcgattcc
     1801 cgtttatggt cgggtttacg tgcacaggca acttcaaggt caacattgag tttgatgacc
     1861 agatcaggct tatggctcgc catccagtga aacgctttac gttcctggct tgccagccat
     1921 gagacaaaac gaccaccttc aatgttaggt gggaacaccg taccatcgta agcgccagga
     1981 atttggtcct gaggataacg gtcggttaga acaattaacc cgcgacgacg acaggcaagc
     2041 atatgacgaa agcgcagtaa gcgacgggcg acaaacgctg taattaccag cgccggaact
     2101 ggtcaaggca atttttttgc tgttttcacc tgatttcgtt caattgtttt atgtaaggat
     2161 tttcccatca acggtaattt tgtcactgca cgaccgacat ttccggcctg ttttcctaaa
     2221 tgaactcttt cggcagcacc atatttttcg acaacggtaa taagatgttc acacatcgtt
     2281 gacttgcctg aaccatcgct accaataacg gcaattaatg gaggtgttat tgactgcatg
     2341 aatatatcct ttaatttaaa tatccattaa aaatatttat ttggttaata tgtttttatg
     2401 aaagcgtaat tcaggtcaat gtcacaatta accattgtca caataaggtt gaacggatat
     2461 tctgagcacg gaccacgtaa tattcaatac attatttact gccgggtttt tcgtgaatca
     2521 acgtaatatg tcaataatta attccacgcc agtgcgtgtt attgccattg taggatgtga
     2581 tggttcaggt aaatcgaccc tcacggcaag cctggtaaat gaactggcag caagaatgcc
     2641 aacagaacac atttatctcg ggcaatcgtc cgggcgaatt ggcgaatgga tttcacagct
     2701 ccctgttatt ggcgcacctt gtgggcgtta tctgcgaagt aaagcggcac atgtgcacga
     2761 aaaaccctca acaccgcctg gcaatattac tgcgctggtt atctatctgc tttcctgctg
     2821 gcgggcgtac aagtttcgca aaatgttgtg taaaagccag caaggctttc tgctcatcac
     2881 cgaccgctac ccgcaggttg aagtgccggg ttttcgcttt gatggcccgc aattggcaaa
     2941 aaccacgggc ggtaacggtt ggataaaaat gttaaggcag cgcgagctga agctgtacca
     3001 atggatggca tcttatttgc ccgtattgtt gattcgtctt ggcattgatg aacaaaccgc
     3061 gtttgcgcgt aaacctgacc accaactggc agcgttacag gaaaaaatcg ccgttacgcc
     3121 gcaactgaca ttcaatggcg caaagatcct tgaactggat gggcgacacc ccgccgatga
     3181 aattctgcaa gcgtcactac gcgcaattca cgccgcgctt tcctgatcac caaaatggat
     3241 aggggatgat ttaacgaatg gatgcactac aaactcaaac tgttaatagt acaaccgcgc
     3301 cgcagcccaa ctacattccg gggctgattg cggtggtcgg gtgtgatggc accggtaaat
     3361 ccacactgac caccgacctg gtgaaatcgc tgcaacaaca ctggcaaacc gagcggcgct
     3421 atctggggct gctctccggc gaagacggcg acaaaatcaa acgattgccg ttggttggcg
     3481 tctggctgga acggcgactg gcggccaaat cctcgaaaac ccaaagcatg aaaaccaaat
     3541 ctccggcgct atgggcggcg gtgattatgt actgcttctc gctgcgaaga atggcgaatc
     3601 tacgcaaggt tcagcgactg gcgcaaagtg gcgttctggt ggtcagcgat cgcttcccgc
     3661 aggctgaaat ttcgggcttt tattatgatg gaccggggat tggcgtcgaa cgtgcgaccg
     3721 ggaaaatcag catgtttctg gcgcagcgcg aacggcgttt ataccaacaa atggcgcaat
     3781 atcgcccgga attaattatt cgcctgggca ttgatattga gactgccatc tcccgcaagc
     3841 ctgaccatga ctatgccgag ctgcaggaca aaatcggtgt catgtcgaag attggctata
     3901 acggcacaaa aattcttgag attgattcca gagcgcccta cagcgaagtg ctggaacagg
     3961 cacagaaggc ggtttctctg gttgccatcg tttctgaccg ccgaagttta acttaaggct
     4021 ggcgggatac tttttactat caacgataag gtcaggctga attggcgggt tttaacatca
     4081 aacattggtt tgcagatggc gcgtttcgca ccattattcg caatagcgcc tggttaggct
     4141 ccagtaatgt cgtgagcgcc ttgctggggc tgttggcgct ctcgtgtgcc ggtaaaggga
     4201 tgacgcccgc catgtttggc gtactggtga ttgtgcaatc gtacgccaag tcgatcagcg
     4261 attttattaa gtttcagaca tggcagctgg tggttcagta cggaacgcca gccttgacca
     4321 acaataatcc gcagcaattt cgcaatgtcg tctcattttc cttctcgctg gatatcgtca
     4381 gcggcgcggt ggcgattgtc ggcggcattg ccttactgcc attcctttcc cattcattag
     4441 gtctggatga ccaaagcttt tggctggcgg cgctgtattg cacgctcatt ccttcaatgg
     4501 cttcctccac gccgaccggc attctgcgtg cggtagatcg cttcgattta attgctgtac
     4561 agcaggcgac gaaacctttt ctgcgcgcag cggggagcgt cgtagcctgg tattttgact
     4621 ttggttttgc gggttttgtt attgcctggt acgtgtcgaa tctggttggc ggcaccatgt
     4681 actggtggtt tgcagcgcgc gaattacgcc gcagaaatat ccataatgcc ttcaaattga
     4741 atctgtttga gtctgcccga cacatcaaag gcgcgtggag ttttgtctgg tcaaccaaca
     4801 ttgcccactc catctggtcg gcgcgtaact cgtgcagcac agtgctggtg gggatcgtgt
     4861 taggacccgc tgccgccggg ttatttaaaa tcgccatgac attcttcgac gccgccggaa
     4921 cgccagcggg tttgctgggt aaaagttttt acccagaggt gatgcgttta gatccgcgca
     4981 ccaccagacc gtggttgtta ggtgtgaagt ccggtttact ggcgggcgga atcggtattc
     5041 tggtggcgct cgcggtgttt atcgtcggca agccgctcat ttcgctggtg tttggcgtta
     5101 agtatctcga agcgtatgac ctgattcagg tgatgctggg cgcaattgtg atttcgatgc
     5161 tgggcttccc tcaggagtca ttgctattga tggcgggaaa acagcgcgct tttctcgtgg
     5221 cgcaaaccat cgcctcaatc ggctacatcg tattgctgtt catgttctgt catctgtttg
     5281 gtgtgctggg agcagcgttt gcttgcttcg gtgggcaatg tctggacgtg gcgctctcgt
     5341 taattccaac cttaaaggca ttttttcagc gccattcctt gctttataac gcagccggag
     5401 agaaatcctg atgatgagaa aatatttccc gcttgaggcg agcgagcgtc tatttgttgc
     5461 gattgaagaa gatgatgtcg ttgatgcaca ggttagtttg ccgccgacta ttgcactaag
     5521 ttgtaccacc gaaatcattc atgataatta cgcgttatgc ctgcaattct ggctcaatgg
     5581 cgttgatcgt caggaattac tgcgtttagt tcgcaaacaa gccaaaggcg atgagctgac
     5641 tgctgatgag cgcaaacaat ttaaatacat gcgagcgcgc tacaagcacc tgcgttttgc
     5701 gcaacggctg tatttaaaga agcatcaggc cggattttta ttcggcaaaa cgaccgtttt
     5761 tctggggcgt tttcaggacg gctttcgtaa cggtaagaaa aatattgtgt cgtattacgg
     5821 caacctgtta cggatttatt taagctctcc ggtctggtcg ttggtgaact attcattacg
     5881 ccatagccag ttagaaagcg taagcggttt tattgcctat cggcaaaagc aaatgcatac
     5941 cctgaaagag attattgcca aaccgcgact aaccggcagg gaatttcatg atgtgcgaaa
     6001 aatcatcagc caacaggttt cttattacga caccttaaga tcgcttgatc ctgaaaataa
     6061 agaggcgtta cagatttccc gtttcctcgc cgccattaat ggcctgatgg gagataaaca
     6121 cgacgacatg gtggcggatg atatggaaaa ccgccagtcg tatgatgcac cgttggcgct
     6181 ggatagcgat attcgtcagc gcttagagct gctgatttcg cgttttccgc tatagccgga
     6241 gcaatgatgt catctcgttt gattattgcg ttgattatca tgctcttagc cccgggtgtg
     6301 caggcacaca atttcgtcac tggcaaaacg gttacccctg tttatatcca ggaaggcggc
     6361 gagctgcttc tgaatagcga cgacgaaatt cactaccaaa agtggaaaag cacacaatta
     6421 gcgggaaaag tccgcattat tcagtatatc gccgggcgta agtcggcgaa gaaaaagaac
     6481 tcactgttaa ttaaagcggt tgaagcggca aactttccgc aggatcgttt tcagcccacc
     6541 accattgtga acaccgatga tgccatcttt ggtactggct attttgtcgt tggcaaaatc
     6601 gaaaaaaata aacgccgcta tccgtgggcg caattcatta ttgacggcaa tggacaggga
     6661 cgcgttgcct ggcgcttgcc ggagcagagt tcaaccattc tggtgctgaa taaagccggg
     6721 caaattcagt gggcaaagga cggcagcctg acgccggaag aggtagatca tgtcattgcg
     6781 ttggcgcaga aactgatcaa tgaataaaaa actcaaagga ttgagggcgt tagttagatg
     6841 aagctggttg aacactacat catgcgtggt acgcgccgtc tggtgctgat tatcgtcggt
     6901 tttctgatct ttattttcgc cagctactcc gcacagcgtt atctgaccga agcggcaaat
     6961 gggacattag ctcttgatgt tgtgctggat atcgttttct acaaagtgct gattgcactg
     7021 gagatgttgt tacttgttgg tctgtatgtg tcagttggcg tgacgctagg gcagatgtat
     7081 accgactcgg aaattaccgc tatctctgcg gcggggggca gtccgggacg cttgtacaaa
     7141 gccgttcttt atctggcgat accgctaagt atttttgtca cccttctgtc gatgtatggt
     7201 cgtccgtggg cttatgcgca gatttatcaa ctggagcagc agtcgcagtc ggagctggat
     7261 gttcgccagt tgcgggcaaa gaaatttaac actaacgata acggacgaat gatcctttcg
     7321 cagacggttg atcaggataa taatcgcctg actgacgcgc tgatttatac ttctactgcc
     7381 aatcgaaccc gtattttccg cgcccgttcg gttgatgtgg ttgacccatc acccgagaaa
     7441 ccgaccgtta tgttgcacaa cggcactgcc tatcttctcg atcatcaggg gcgtgacgac
     7501 aacgaacaga tctaccgtaa tctgcaatta catctgaatc cgctggatca aagccctaac
     7561 gtcaaacgca aagcaaaatc ggtcacggag ctggcgcgct ccgcctttcc tgccgatcat
     7621 gccgaactgc aatggcgaca aagccgtggc ctgaccgcat tgttgatggc gctgctggcc
     7681 atttcattaa gtcgggtaaa accgcggcaa gggcgatttt caacgttatt gccactgacg
     7741 ttgctgttta ttgccatttt ttatggcggc gacgtctgcc gtacgctggt ggctaacggc
     7801 gcgattcctc tcattcctgg tttgtggtta gtgcccggac tcatgctaat gggcctgctg
     7861 atgctggtcg cacgcgactt ctctttgctg cagaaatttt cccgatgaat gttttcagtc
     7921 gctatttaat ccgtcatctc tttctcggtt ttgccgccgc cgcagggcta ttgctgccgc
     7981 tttttaccac cttcaacctg attaacgaac tggatgatgt cagtccgggc ggttatcgct
     8041 ggactcaggc ggtgctggtg gtgctaatga ccttaccgcg cacactggtc gaactttcgc
     8101 cgtttatcgc cttattgggt gggattgttg gcctggggca gttatcgaaa aacagtgagc
     8161 ttaccgccat tcgcagcatg gggttttcta tcttccgtat tgcactggtg gcgctggttg
     8221 cagggatatt gtggactgtt tcgttaggcg cgatagatga gtgggtggcg tcgccattgc
     8281 agcaacaggc gctgcaaatc aaatcgaccg ccaccgcgtt gggggaggac gatgacatta
     8341 ccggcaatat gctgtgggcc aggcgcggca atgaatttgt gacggtgaaa tcgctgaatg
     8401 aacagggcca gcctgtgggc gtggagattt ttcattatcg tgacgatctt tcgctcgaat
     8461 cctacattta tgcacgcagt gccaccatta aagacgacaa aacgtggatt ctgcatggtg
     8521 tgaatcataa aaaatggctg aatggcaaag aaacgctgga aatattagat aatcttgcct
     8581 ggcaatcgac attcaccagt atgaatcttg aagaactgtc gatgccgggc aatagctttt
     8641 ccgttcgtca gctcaaccat tacatcaatt acttgcagga aaccggacaa ccgagcagtg
     8701 agtatcgcct ggcattgtgg gaaaagctgg ggcatcccat tttaaccctg gcgatgattt
     8761 tgctggcagt gccttttacc tttagcgccc cgcgctcgcc ggggatgggc agccgtcttg
     8821 ctgtaggcgt catcgttggc ttacttacct ggataagcta ccaaataatg gtcaatctgg
     8881 gattattatt tgcgctgagt gcgcccgttg ctgcactcgg tttacctatg gcatttgtgc
     8941 tggcggcgtt gattctggtg tatctatttg ataggcaaca ttaaacccgc cgtggcgcaa
     9001 caccacggcg ggctcacatt actgcttcag agtagcaaat gcctgaatga tggcatcgat
     9061 ttgctcacga ctgtgggcag cgtttacgct acagcgcagc agcgtgatgc ctgcaggcgc
     9121 ggcaggtggc aggataagat tcacataaac gcccagcgaa ataagctcgc gccagatgcg
     9181 taaaccttcc tctttcgaac cgattattac cggcactacc gggctaatat gtgaacttaa
     9241 ctcataaccc agtttttgca gaccgtcata cagatggttg gcgttatcca tcagcttttg
     9301 ccgcagctct ggttgtgtgg caatagttct taacgacgag cgcacggtcg caatgcagga
     9361 cggagaagga gaggcggtaa aaatatacgg gcggctgccg tagcgcagca cttccatcgc
     9421 ttccgaaccg acagcaaaac cgccaatcga ggccagactt ttactgaaag taccaacgat
     9481 aatatccaca tcatcttcaa cgccgacagc ttcagccagt ccgcgccccg ttgcgcctaa
     9541 cacgccaaac gaatgcgctt catcgacaat caaataacca ccgagacgac gtttgatatc
     9601 aacaatttcc gccagcggcg caacgtcacc gagcatgctg tagatgccct caacgatgat
     9661 aatcgcctct ttcgcccgtt caccgaggcg aaccatgcgc cgttccagat ctttagcatc
     9721 gttatggcgg aaacgaataa tttccgcgcc accgagagaa caggcgtcat aaatactggc
     9781 gtggctgtcg gcatccagta acaccacggc gttatggtcg gcaagtgcgc tgatgacgcc
     9841 taaattagcg gtataaccgg ttgaaaaaac gatagcggta gggcgcttga aaaactcggc
     9901 aatttctttc tctaacgcca ggtgcggcgc ataactgccg tttgccatac gagaaccggt
     9961 ggtgccggtg ccttgggccg ctaacgctgc ctgaccttcg ctgatggcat catgattaaa
    10021 ggttaaaccg agataattat tggtcccggc cagaatcact tttttattgc cgatccggcc
    10081 ttcggtggcg gaatacactt catcaataca ggtgccaaac ggtgttaacc cgttgtcact
    10141 aaattgcaga cgctcgccag caaggcgcgc atatttatcg tatagcccca ttatttattc
    10201 tccagccatg gaagtagagt ttccattaat tgcgcagggg ttttgacatc cagcagaata
    10261 ttaataggaa tggaaatatc gaatctgtct tccagcatca ttaagagatc catcactttg
    10321 atcgactcca ggccaagatc gttgacgaga tcgctgtcgg gcttaatttc cacaccgttt
    10381 tcgaccaaat cctgtaaaca ggaaaggatg taatccatta ctatttcacg atttaccata
    10441 gaaacgttaa cacaccttta aacaagacaa tcaaaatagc ccgttgcgta atgcttgttc
    10501 caggctaatc ccgggaaacc aattaatatc ttcagaaata cggttattac ttgccgacca
    10561 gtcggcgtgg gttaattcac gaattttcga gcgggtcagc ataggttctt tacctgccag
    10621 gcgactcaac gcggtactga tatccgcaag gcaggtgagt accggcagag gaataccaac
    10681 cattcgcacg gaaccacaac gggcgtcggc ggcaagctgt cgtacgtgtt gccagtcata
    10741 gccgccgggg acgccatcgc ataattcata ggtttgcgtc tgtacagttt cggcgcttaa
    10801 ccactgaccc actgcttgcg cgaaatcggt gacgtgcagg aaagagagct gtgtatctgg
    10861 cgcaccaagt cgtggcagca ggccgcgcag catccagtca aacagcggtt ttaactcttt
    10921 atcgccggga ccatacacgg ctgtcgggcg aaaaacgccc agcgtaattt cgtcagccat
    10981 tgcagtcaga cgttgttcgg cgacgtgttt ggaatttgcg taccaggaga gctcgggatg
    11041 gcgcgccgcc agcgaagaga taaacagaaa acgttggcaa aagccgctct cttttgctgc
    11101 ttgcatcagg cgcaggctgc cgtcaacgtt acagcgggtg aaaatctctt ctttgtgccc
    11161 gcgcacttgc ccggcgcaat ggaccactgc gctggctccg gcaaccagct tgctaagtga
    11221 atgagtatct tccagcgaac cgcgcaccca ggtgagatta tcattgacgt gagcgcgggc
    11281 agtacgcgtc aatgcgcgaa cgtgaaagcc gcgggcgagc aggttatcga taatatattt
    11341 accgataaac ccggtagcgc ccgtcaccgc gacagtttga ttcatgccag ggattcctgc
    11401 acatgaaggc ttgcagcata agccttctga taacgttttt tcgcttccgc acgggcaggc
    11461 ttgccggagg atgttcgggg aatactgtgg ggcggcaaca gatcgatagc cgctgttacg
    11521 ccaaattcgc tttggatccg tgctgccagc gcgtggataa gctgcccgcg acgttcttcg
    11581 tcgctgatcc gacactggat ctgcaaaatg attttttcct gggcggtaac aaaagcaatc
    11641 gcatcgccag aatgaatttc cggttcttgt tccgcaatat attcaatatc ctgcggccag
    11701 atattacggc cacgaataat aatcagatct ttaatacgtc cggtgacata cagataaccg
    11761 tccagcagat aaccgaggtc gccggtgtct aaccagcccg tcgcggcaat ctcgtcttgc
    11821 gaagcctggt cgccaaagta accgctcatc agactggggc cggagatgca aatatggcct
    11881 accacacgtt ccgcgaccgg catacctgct tcattgcgga tttcaatacc atgttccggc
    11941 aacgctttgc cgcagttgac gaaagtcgat acggcgcgtg tctctgcacc cggcgcgacg
    12001 gctttaccct gatattcgag gatgtcgcga tccacttcgt taaccacaac cccagagcct
    12061 tcatcagaga agctgacagc cagcgcattt tctgccagtc cgtagcacgg catgaacgtt
    12121 ttatcgtcaa agttaacctg acggaaacat tcagcgaatt gatggagttg ttctgcggag
    12181 atcggctcag caccaatacc agcgacgcgc cagcaggaaa gatccagttc agcgagatct
    12241 ttttcattca cgcggcgttg gcacaattca tagccaaacg gcggcgcaac ggaaacggtg
    12301 ccgcgatttt tactgatcaa tttaagccat tgcaaaggac gcatggcaaa atcctgagtg
    12361 cgcaaataat ctactgaaag ttgcgtggcg acgggggtca ggagaaagcc gaccagtccc
    12421 atatcatggt agaaaggcag ccaggagacg cagcggtcgc cagggcgtaa tttaatgcca
    12481 tcgtggctta tagcacgtag attagccatc acttcgcgat gggtgataat gacgccacgg
    12541 ggaaaacggg tgctgccgga ggtgtactgg aggtaggcga tatcgttcgg aactggacgc
    12601 tggagcgcaa catcggcttc cggtaatgcc ttaaaccagg cgtggcttaa aacatgtaat
    12661 tcggggttgt tatgcgtcgc ggcattgacc agtggcaacc actcatcacc agtgataatg
    12721 gctgcgggct ggcaacttgc cagtaaaccc tggagtttgg cgctccagga atcccgctga
    12781 ccgacgccca ttggaatcgc caacgggacg gcgactaagc cagcatactg acaggcaaaa
    12841 aaagcctcta caaacccgct actcgtttcg gcaatcagcg ccacgcgttc gccttttttc
    12901 aggttcagcg ataacaaccg cttcgcacca gcttcggcac gcgtttttaa cgtctgatat
    12961 tccagttgat cttcaagttg gcaacgtctg tcataaaaat tcattccggc gctactcaga
    13021 gcggcgtagt ccaaagcatc aaccagcgtt ggaaaatcgg catagcgcat aggtagggaa
    13081 tgcgtaaaga ttttattaga catatacacc acgaaaaaat tggatatcaa aaataaaatg
    13141 acaataatgc ggtggattat ataggcataa aagataaatg agatagtatt ttcatcggtg
    13201 tgaaaatgaa cattgattta aataatgagt ttaagttttt tgtttttatt gtgaatgata
    13261 tttaatttat gaatatatta agaagaagcc ttgtccggtc gccttaaatc gacaaaaggc
    13321 attgaggc
//
LOCUS       DAPOAV010000100        13302 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.100, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000100 DAPOAV010000000
VERSION     DAPOAV010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13302
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.100"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..1083
                     /gene="ecpC"
                     /locus_tag="RN951_003680"
                     /gene_synonym="yagX"
     CDS             <1..1083
                     /gene="ecpC"
                     /locus_tag="RN951_003680"
                     /gene_synonym="yagX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher EcpC"
                     /protein_id="HDX2528623.1"
                     /translation="RAIGGTLNLNSLWSKLGTFSISYNDDRRYNSHYYTADYYQNVYS
                     GTFGSLGLRAGIQRYNNGDSNANTGKYIALDLSLPLGNWFSAGMTHQNGYTMANLSAR
                     KQFDEGTIRTVGANLSRAISGDTGDDKTLSGGAYAQFDARYASGTLNVNSAADGYVNT
                     NLTANGSVGWQGKNIAASGRTDGNAGVIFNTGLEDDGQISAKINGRIFPLNGKRNYLP
                     LSPYGRYEVELQNSKNSLDSYDIVSGRKSRLTLYPGNVAVIEPEVKQMVTVSGRIRAE
                     DGTLLANARINNHIGRTRTDENGEFVMDVDKKYPTIDFRYSGNKTCEVALELNQARGA
                     VWVGDVVCSGLSSWAAVTQTGEENES"
     gene            1073..2716
                     /gene="ecpD"
                     /locus_tag="RN951_003681"
     CDS             1073..2716
                     /gene="ecpD"
                     /locus_tag="RN951_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial adhesin EcpD"
                     /protein_id="HDX2528624.1"
                     /translation="MRVNLLITMIIFALIWPVTALRAAVSKTTWADAPAREFVFVENN
                     SDDNFFVTPGGALDPRLTGANRWTGLKYTGSGTIYQQSLGYIDNGYNTGLYTNWKFDM
                     WLENSPVSSPLTGLRCINWYAGCNMTTSLILPQTTDASGFYGATVTSGGAKWMHGMLS
                     DAFYQYMQQMPVGSSFTMTINACQTSVNYDASSGARCKDQASGNWYVRNVTHTKAANL
                     RLINTHSLAEVFINSDGVPTLGEGNADCRTQTIGSRSGLSCKMVNYTLQTNGLSNTSI
                     HIFPAIANSSLASAVGAYDMQFSLNGSSWKPVSNTAYYYTFNEMKSADSIYVFFSSNF
                     FKQMVNLGISDINTKDLFNFRFQNTTSPESGWYEFSTSNTLIIKPRDFSISIISDEYT
                     QTPSREGYVGSGESALDFGYIVTTSGKTAADEVLIKVTGPAQVIGGRSYCVFSSDDGK
                     AKVPFPATLSFITRNGATKTYDAGCDDSWRDMTDALWLTTPWTDISGEVGQMDKTTVK
                     FSIPMDNAISLRTVDDNGWFGEVSASGEIHVQATWRNIN"
     gene            2685..3395
                     /gene="ecpE"
                     /locus_tag="RN951_003682"
     CDS             2685..3395
                     /gene="ecpE"
                     /locus_tag="RN951_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414823.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone EcpE"
                     /protein_id="HDX2528625.1"
                     /translation="MFRRRGVTLTKALLTAVCMLAAPLTQAISVGNLTFSLPSETDFV
                     SKRVVNNNKSARIYRIAISAIDSPGSSELRTRPVDGELLFAPRQLALQAGESEYFKFY
                     YHGPRDNRERYYRVSFREVPTRNHTRRSPTGGVVSTEPVVVMDTILVVRPRQVQFKWS
                     FDKVTGTVSNTGNTWFKLLIKPGCDSTEEEGDAWYLRPGDVVHQPELRQPGNHYLVYN
                     DKFIKISDSCPAKPPSAD"
     gene            3708..4037
                     /locus_tag="RN951_003683"
     CDS             3708..4037
                     /locus_tag="RN951_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HDX2528626.1"
                     /translation="MSNLNPCMTCGACCAFFRVSFYWAEADDAGGTIPARLTEQISPF
                     HRCMSGTNQKNPRCIALAGTPGKNACCTIYKNRSSTCREFAMSGENGVVNEACNRARA
                     KYGLTPL"
     gene            complement(4285..4899)
                     /locus_tag="RN951_003684"
     CDS             complement(4285..4899)
                     /locus_tag="RN951_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YagU family protein"
                     /protein_id="HDX2528627.1"
                     /translation="MNIFEQTPPNRRRYGLAAFIGLIAGVVSAFVKWGAEVPLPPRSP
                     VDMFNAACGPESLIRAAGQIDCSRNFLNPPYIFLRDWLGLTDPNAAVYTFAGHVFNWV
                     GVTHIIFSIVFAVGYCVVAEVFPKIKLWQGLLAGALAQLFVHMISFPLMGLTPPLFDL
                     PWYENVSEIFGHLVWFWSIEIIRRDLRNRITHEPDPEIPLGSNR"
     gene            5317..6006
                     /gene="paoA"
                     /locus_tag="RN951_003685"
     CDS             5317..6006
                     /gene="paoA"
                     /locus_tag="RN951_003685"
                     /EC_number="1.2.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase iron-sulfur subunit"
                     /protein_id="HDX2528628.1"
                     /translation="MSNQGEYPEDNRVGKHEPHDLSLTRRDLIKVSAATAATAVVYPH
                     STLAASVPAATPAPEIMPLTLKVNGKTEQLEVDTRTTLLDTLRENLHLIGTKKGCDHG
                     QCGACTVLVNGRRLNACLTLAVMHQGAEITTIEGLGSPDNLHPMQAAFIKHDGFQCGY
                     CTSGQICSSVAVLKEIQDGIPSHVTVDLVSAPETTADEIRERMSGNICRCGAYANILA
                     AIEDAAGEIKS"
     gene            6003..6959
                     /gene="paoB"
                     /locus_tag="RN951_003686"
     CDS             6003..6959
                     /gene="paoB"
                     /locus_tag="RN951_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde oxidoreductase FAD-binding subunit
                     PaoB"
                     /protein_id="HDX2528629.1"
                     /translation="MKAFTYERVNTPAEAALSAQRVPGAKFIAGGTNLLDLMKLEIET
                     PTHLIDVNGLGLDKIEVTDAGGLRIGALVRNTDLAAHERVRRDYAVLSRALLAGASGQ
                     LRNQATTAGNLLQRTRCPYFYDTNQPCNKRLPGSGCAALEGFSRQHAVVGVSEACIAT
                     HPSDMAVAMRLLDAVVETITPEGKTRSITLADFYHPPGKTPHIETALLPGELIVAVTL
                     PPPLGGKHIYRKVRDRASYAFALVSVAAIIQPDGSGRVALGGVAHKPWRIEAADAQLS
                     QGAQAVYDTLFASAHPTAENTFKLLLAKRTLASVLAEARAQA"
     gene            6956..9154
                     /gene="paoC"
                     /locus_tag="RN951_003687"
     CDS             6956..9154
                     /gene="paoC"
                     /locus_tag="RN951_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde oxidoreductase molybdenum-binding
                     subunit PaoC"
                     /protein_id="HDX2528630.1"
                     /translation="MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWHEE
                     APNAAYGYIVGSAIAKGRLTALDTDAAQKAPGVLAVITASNAGALGKGDKNTARLLGG
                     PTIEHYHQAIALVVAETFEQARAAASLVQAHYRRNKGAYSLADEKQAVNQPPEDTPDK
                     NVGDFDGAFTSAAVKIDATYTTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRT
                     DLAKTLKVPVENVRIISPYIGGGFGGKLFLRSDALLAALAARAVKRPVKVMLPRPSIP
                     NNTTHRPATLQHLRIGADQSGKITAISHESWSGNLPGGTPETAVQQSELLYAGANRHT
                     GLRLATLDLPEGNAMRAPGEAPGLMALEIAIDELAEKAGIDPVEFRILNDTQVDPADP
                     TRCFSRRQLIECLRTGADKFGWKQRNATPGQVRDGEWLVGHGVAAGFRNNLLEKSGAR
                     VHLEQNGTVTVETDMTDIGTGSYTILAQTAAEMLGVPLEQVAVHLGDSSFPVSAGSGG
                     QWGANTSTSGVYAACMKLREMIASAVGFDPEQSQFADGKITNGTRSATLHEATAGGRL
                     TAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATGEVRVRRMLAVCAAGRILNPKTARS
                     QVIGAMTMGMGAALMEELAVDDRLGYFVNHDMAGYEVPVHADIPKQEVIFLDDTDPIS
                     SPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPITLDKLLDKLPDVV"
     gene            9164..10120
                     /gene="paoD"
                     /locus_tag="RN951_003688"
     CDS             9164..10120
                     /gene="paoD"
                     /locus_tag="RN951_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor insertion chaperone PaoD"
                     /protein_id="HDX2528631.1"
                     /translation="MSYPLFDKDEHWHKPEQAFLTDDHRTILRFAVEALMSGKGAVLV
                     TLVEIRGGAARPLGAQMVVREDGRYCGFVSGGCVEAAAAFEALEMMGSGRDREIRYGE
                     GSPWFDIVLPCGGGITLTLHKLRSAQPLLAVLNRLEQRKPVGLRYDPQAQSLVCLPTQ
                     TRTGWNLNGFEVGFRPCVRLMIYGRSLEAQATASLAAATGYDSHIFDLFPASASAQID
                     TDTAVILLCHDLNRELPVLQAAREAKPFYLGALGSYRTHTLRLQKLHELGWSREETTQ
                     IRAPVGIFPKARDAHTLALSVLAEVASVRLHQEEDSCLPPSS"
     gene            10171..10509
                     /locus_tag="RN951_003689"
                     /pseudo
     CDS             10171..10509
                     /locus_tag="RN951_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308332.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            11023..11499
                     /locus_tag="RN951_003690"
     CDS             11023..11499
                     /locus_tag="RN951_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002437139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HDX2528632.1"
                     /translation="MTSNTARTILMDMVDTKITTIKAKCRRNKRFFQFFTAGSIILSA
                     SITVVVGLEWPNHAAIQKNIALIMGVSLTLINGWVAIFDFKKLWMRQKNTLFGLYLID
                     NELKILTDSDEDKLRVKELFNAYQAVWEKDGSEWANIFSSDIESSKITQNIKELQS"
     gene            11496..12584
                     /locus_tag="RN951_003691"
     CDS             11496..12584
                     /locus_tag="RN951_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002437141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HDX2528633.1"
                     /translation="MNFVHLKVDKIAIHQIFPRGEDGKEVLPGKGTELINFDEDALSD
                     FKQRIYNSLGHDSSAVEMVITNEKTESTPFYVNILHGCNDVEFINNSYEIAKNLSKAQ
                     KRRGMSGGILVVFSATYQYNKLPFVGIIKADLYSGYEKWQDKKTGIISLKHVKELLLT
                     PSTKLYKSAGFFKRENVKNDSTLSEQWAVHISDYQIDKSDGKAAAQYFYQTFLGCDYP
                     ATSARTTKRYFEIACDFINQMDIDEEERTHLHNVLYADLKAGKSQKVDPMAFAGSYMS
                     TADVDNFRNYLDDYDFPVGPFIKDTQYISSKLKNRRLKFSKNIRISAPSEIFEEFVSI
                     ETVEGEAGQDGYRPTWTKILVKDRIVDQ"
     gene            12584..>13302
                     /locus_tag="RN951_003692"
     CDS             12584..>13302
                     /locus_tag="RN951_003692"
                     /inference="COORDINATES: protein motif:HMM:NF016488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RelA/SpoT domain-containing protein"
                     /protein_id="HDX2528634.1"
                     /translation="MTETEFLKQWHSEKAMYGAWGQYIVSSISEALIKSLKVDLKNYL
                     KIPVNHRVKDDGSLVDKALYRNKAYKNPYNDIEDKVGVRFVVMLQTDVEKVCEVIKQV
                     AVQEGWDATQCRNYNEERRESPMLFTYQSHHFIIRNKRAFTHGGILIHENTPCEVQVR
                     SLLQHAYAELTHDAIYKKKTIIEPDVVRTVAKTMAFIETADEFFQKVVDRTESENILK
                     NESFLDTLFEQITGVQPIKQNS"
BASE COUNT         3536 a         3325 c         3340 g         3101 t
ORIGIN      
        1 cgtgcaatcg gcggcacact caacctgaac tcactgtggt cgaagctggg cacattcagc
       61 atcagctaca atgatgaccg ccgttacaac agccattatt acacggcaga ttactatcaa
      121 aatgtctaca gcggtacctt tggttcgctt ggcctgcggg ccggtattca gcgctataac
      181 aacggcgaca gcaacgccaa tacaggaaaa tatatcgctc tcgatctctc gctaccactg
      241 ggcaactggt ttagcgcagg gatgactcat caaaacggct acaccatggc aaacctgtca
      301 gcacgcaaac agtttgatga aggaaccatt cgcactgttg gtgccaatct gtcacgtgcc
      361 atctccggcg ataccggtga tgacaaaacc ctcagcggcg gggcgtatgc acaattcgac
      421 gctcgttacg ccagcggaac gctgaacgtc aatagcgcgg cggacggcta cgtcaatacc
      481 aacttgaccg ccaatggcag cgtcggctgg cagggtaaaa acattgctgc cagcgggcgg
      541 actgatggca acgctggggt gatattcaac accgggctgg aggacgacgg tcagatcagc
      601 gccaaaatca acgggcggat tttcccgctt aacggcaagc gtaactatct cccgctctct
      661 ccctatggaa gatatgaggt ggagttacag aacagcaaaa actcactcga cagttacgat
      721 atcgtcagcg gccgcaaaag tcgtctgact ctctatccag gcaatgtcgc tgtcattgag
      781 ccagaggtga agcagatggt taccgtctcc ggtcgtatcc gtgcggaaga cggcacactg
      841 ctggctaacg cacggattaa caaccatatc ggccgaaccc gaaccgatga aaacggcgag
      901 tttgtcatgg acgtggataa gaaatacccc actatcgatt ttcgctacag tggcaataaa
      961 acctgcgaag tggctctgga actcaaccag gcgcgcggtg ccgtctgggt cggtgatgtg
     1021 gtctgcagcg gcctctcatc gtgggcggcg gtgacgcaga caggagaaga gaatgagagt
     1081 taacctacta ataacgatga taattttcgc gctaatctgg ccagtaactg cgctcagagc
     1141 ggcagtgagc aaaacaacct gggcggatgc accggcacgc gagtttgtgt ttgtcgaaaa
     1201 caactcagac gacaactttt tcgtcactcc tggcggggcg ctggatccgc gcctgaccgg
     1261 tgccaaccgc tggaccggtt taaaatacac tggttcagga accatctatc agcaaagcct
     1321 cggctacatt gataacggtt acaacaccgg cctttatacc aactggaagt ttgatatgtg
     1381 gctggaaaat tcaccagttt catctccttt aactggcttg cgctgcatca actggtacgc
     1441 tgggtgtaat atgaccacca gtcttatcct gccgcaaacc accgacgcca gtggatttta
     1501 tggcgcgacg gtgaccagcg gcggcgcgaa gtggatgcac ggcatgttgt cagacgcgtt
     1561 ttaccagtat atgcaacaaa tgcccgtcgg cagcagcttt acaatgacca tcaatgcctg
     1621 ccagacctct gtgaactatg acgccagcag cggcgcacgc tgtaaggatc aggcctccgg
     1681 caactggtat gttcgcaacg tcacccatac gaaagcagca aatctacggt tgataaatac
     1741 ccactcgctg gcggaagtat ttatcaacag cgacggagta ccgactctgg gcgaagggaa
     1801 cgccgactgc cggacgcaaa ccatcggcag ccgttcagga ttaagttgta agatggttaa
     1861 ctataccctg caaacaaacg gactcagcaa cacctcaatc catatattcc cggcgatcgc
     1921 caactcgtcg ttagcctcgg ccgtcggggc gtacgatatg cagttcagtc tgaatggcag
     1981 ttcatggaaa ccggtgagca ataccgccta ttactacacc ttcaacgaga tgaagagcgc
     2041 agactcgatc tatgttttct tctcgagcaa cttctttaag cagatggtga acctcgggat
     2101 cagcgatatc aacaccaaag atctattcaa ctttcgcttt cagaacacca catcaccgga
     2161 gtctggctgg tatgaatttt ctacctccaa cacgctgatt atcaaacccc gtgatttcag
     2221 catcagtatt atctccgatg aatatactca gacaccgtcg cgggagggat atgttggcag
     2281 cggcgagtcg gcactcgatt tcggctatat cgtaaccacc agcggtaaaa cagctgccga
     2341 cgaagtgctg atcaaggtga ccggacccgc gcaggtgatt ggcgggcgct cctattgtgt
     2401 cttcagctcc gatgacggta aggcgaaagt accgttcccg gcgacacttt cctttattac
     2461 ccgcaacgga gctacaaaaa cctacgatgc cgggtgcgat gatagctggc gggatatgac
     2521 cgatgcgctg tggttgacca caccgtggac tgatatctct ggcgaagtgg ggcagatgga
     2581 taagaccaca gtcaaatttt cgattccaat ggataacgcc atttcgctgc gtacggtaga
     2641 tgataacggc tggtttggcg aagtcagcgc ttcaggagag attcatgttc aggcgacgtg
     2701 gcgtaacatt aactaaggcc ctgctgacag cggtctgtat gctggcggca cctttgacac
     2761 aggcgatttc ggtcggcaat ctgacatttt cgctgccgtc cgagactgac tttgtcagca
     2821 aacgtgtagt gaataacaac aaaagcgcac ggatataccg tattgccatc agtgctattg
     2881 atagcccggg cagcagtgaa ttgcgcaccc gaccggtgga tggtgaactg cttttcgccc
     2941 cccgccagct ggcgttgcag gctggtgaga gcgagtattt taaattttac tatcatggtc
     3001 cacgggataa ccgcgagcgc tactaccggg tctcatttcg cgaggtcccc actcgtaacc
     3061 atacaagacg cagcccaacc ggcggcgtgg tcagcacgga gccggtggtg gtgatggata
     3121 ccattctggt agtacgacca cgtcaggttc agtttaaatg gtccttcgac aaggtgacag
     3181 gaacggtaag taacactggc aacacatggt ttaagctact gattaagcca ggatgtgatt
     3241 cgaccgaaga ggaaggcgat gcctggtatc tacgtccggg agacgtggtt catcagcctg
     3301 agttacgtca gccggggaat cactatctgg tctataacga caaattcatt aagattagcg
     3361 attcctgtcc ggctaagccc ccttcggcgg actaagactt atccatcggt cgagggaaga
     3421 attccacctc agagccccaa aaatcgttta aatgatgtgg aagcgatcgt caatatcacc
     3481 tgtaacgatg ggctttctca tatgcacacc atagtgttca ggagacacgg aaaggtatca
     3541 ggcagcctgc taacgagtgg tttaatcacg aattagtacg taaaatcggt aacggctgga
     3601 aatcattcaa tactcacact atcgaaagtt ccccagccaa ccgcggtacg ttcttacata
     3661 cgatgtaccg ctgttctctt tacgattttt agctgtactg gtgaattatg agcaatctga
     3721 atccatgcat gacgtgtggt gcctgttgtg catttttccg cgtctctttt tactgggccg
     3781 aagccgacga tgctggcggt actattcccg ccaggctcac tgaacaaata tccccttttc
     3841 accgatgcat gagcggtacc aatcagaaaa acccccgatg tattgccctt gcaggaaccc
     3901 cgggcaaaaa tgcctgctgc acgatatata aaaatcgatc gtccacatgc agagaattcg
     3961 ccatgtctgg tgagaacgga gtcgtcaatg aggcttgcaa tcgtgcaagg gctaaatacg
     4021 ggctgacacc gttataaaca tacaataatt aattgcactg ccccgccagc gataatagcg
     4081 gggcttcgtt tttcaggggt aacaaaaccc gatacttctt ctatttgcca gcaacaatgc
     4141 ctctcttctg tagcgttctt cggatctaca tcatcctgaa gtagcgcgat atactcactg
     4201 actatctgca tcagaatata aaaagcaatg tttttaacct ataaaaatgg cgctgtattt
     4261 gcgccatttt tatcattcaa tgcattatct gtttgagcct aaagggatct cagggtctgg
     4321 ctcatgagta attctgtttc gtaaatctct gcgaataatt tcaatagacc agaaccagac
     4381 taaatgtcca aaaatttcag aaacattctc ataccacggg agatcaaaca gaggtggcgt
     4441 cagtcccatg agagggaatg aaatcatatg aacaaaaagt tgggctaaag cacctgccag
     4501 taagccctgc cagagtttaa tttttggaaa tacttcagcg accacacaat aaccgacagc
     4561 aaacactatc gaaaagataa tgtgcgtaac accaacccag ttaaagacat gcccggcaaa
     4621 ggtataaaca gccgcattgg gatctgtcag ccccaaccag tctcgaagaa aaatatacgg
     4681 tggattgaga aaattacgcg agcaatcaat ttggcctgca gccctgatta atgattccgg
     4741 gccacacgct gcattaaaca tatccaccgg gctacgtggc ggcaatggaa cttcagcccc
     4801 ccacttcacg aatgcggaaa caacgccagc aatcagccca atgaatgcag caagaccata
     4861 acgtctgcgg ttcggtggag tttgttcaaa tatattcata tctaccctgc ttgtaccatt
     4921 atgttataca cctcttcagg agtattcata aaacaaggca aatgtaaaga actgtattgt
     4981 tttgtataac aagatagttt cctaatcgcc aatgaatata agctccatca tttctcccta
     5041 tttttatatt agaagtgaca gagatttgca gggtgatgta gagctgaaaa tcacaggttt
     5101 ccttattggt ttttgcatcg tacaactaaa gcaataaacc agctcccatc atcatcaaca
     5161 tcccggcgaa catgaattta ttagccgggc tcatagctgc attcgcgttt taagaataat
     5221 cctcctgctg tcgccgacta tgcttaacgt ttaaaaaagc atcagcactc tcgcaacgca
     5281 ctcttatttt cccctttaga ataccggagg cctggtatga gcaaccaagg cgaatacccc
     5341 gaagataatc gggttgggaa gcacgagccg cacgatttaa gtttgacccg tcgcgatctg
     5401 attaaagtga gcgccgcaac agcggcgacc gccgtggttt atcctcattc tacgctggcg
     5461 gcaagcgttc cggcagctac acccgcgcca gagataatgc ccctgacact gaaggtgaac
     5521 ggcaaaaccg agcagcttga ggtggatacc cgaaccacgc tactggacac tttgcgtgaa
     5581 aatctgcatt tgatcggtac caagaaaggt tgcgatcacg gacagtgcgg agcctgtacc
     5641 gtgctggtca atggtcgcag gcttaatgcc tgcctgacgc ttgcagtcat gcatcagggg
     5701 gccgagatca ccaccattga aggcctgggt tcgccagata atcttcaccc catgcaggcg
     5761 gcctttatca agcatgatgg cttccagtgc ggctactgca cctccgggca aatttgctca
     5821 tcagtagcgg tgctaaaaga gattcaggac ggcattccca gtcacgtcac ggtcgatttg
     5881 gtttccgctc cagaaacaac tgccgatgag atccgtgaac gtatgagcgg caacatctgt
     5941 cgctgtggtg catacgctaa catccttgcc gccattgaag atgctgcggg ggagataaaa
     6001 tcatgaaggc gtttacctat gaacgagtga ataccccagc cgaggcggca cttagcgctc
     6061 agcgcgtacc cggcgcaaaa tttatcgcgg gcgggaccaa tctgctggac ctgatgaagc
     6121 tggaaattga aacgcccacc caccttatcg atgtgaacgg cctcgggctc gataagattg
     6181 aagtgaccga cgcgggtggg ctgcgcatcg gcgcactggt acggaacacc gacctggcgg
     6241 ctcacgagcg cgtgcgtcgt gattacgcgg tactctcccg cgccctgctc gctggcgcgt
     6301 ctggtcagtt acgtaatcag gcaaccaccg caggtaatct gctccagcgc acgcgctgcc
     6361 cctattttta cgacaccaat cagccctgca ataagcgcct gcccgggagc ggctgcgcgg
     6421 cgcttgaagg ctttagccgt cagcacgcgg tggtaggcgt aagcgaagcc tgcattgcca
     6481 cccatccgag cgatatggcg gtcgcaatgc ggttgctgga tgcggtggtg gaaaccatca
     6541 cgccggaggg aaagactcgc agtatcacac tggctgattt ttatcaccct ccgggaaaaa
     6601 cgccgcacat tgaaaccgcc ctgcttcccg gtgagcttat cgttgcggtg acgttacctc
     6661 caccgctcgg cggaaaacat atctaccgta aggtgcgcga tcgcgcctcc tacgcctttg
     6721 ccctggtatc ggtcgcggcg attattcagc ctgacggcag cgggcgcgtc gcgctgggcg
     6781 gagtagcaca taagccctgg cgcattgagg ctgcggatgc tcagctatcc cagggggcgc
     6841 aggccgtata tgacacgctg ttcgccagcg cccatcccac cgctgaaaac acctttaaac
     6901 tcctgttggc gaagcgaacg cttgcctccg tactggctga agcgagggca caggcatgaa
     6961 atttgataaa cccgcagggg aaaacccgat cgatcagctg aaggttgtcg gtcgtcccca
     7021 tgaccgcatc gacggaccgc tgaaaactac cggcacggca cgctacgcct acgaatggca
     7081 tgaagaagcc cccaacgccg cctatggcta tatcgtcggt tccgccattg ccaaaggacg
     7141 cctcaccgcc cttgatacgg acgccgcgca aaaagcgccg ggcgtactgg ctgtcattac
     7201 cgccagtaac gccggggcac tcggcaaagg cgacaaaaac accgccaggc tgttaggcgg
     7261 ccccactatt gagcactatc atcaggccat tgcgctggta gtggccgaga ccttcgaaca
     7321 ggcgcgagcg gcggcctcgc tggtgcaggc acactatcgc cgtaataaag gagcttactc
     7381 cctggcggac gaaaaacagg ccgtcaatca gccgccggaa gacacgcccg acaaaaacgt
     7441 cggtgacttt gacggggctt tcacctccgc tgcggtgaag attgatgcta cctacacgac
     7501 cccggaccag agccatatgg cgatggagcc gcatgcctcg atggccgtct gggatggaaa
     7561 taagcttacc ctctggacct caaatcagat gattgactgg tgccgcaccg atctggcaaa
     7621 aacgctgaaa gttcccgtgg agaatgtgcg tattatctcc ccgtatatcg gcggagggtt
     7681 tggcggcaag ctgttcctga gaagcgatgc gctgctggcg gccctcgccg cccgagcggt
     7741 gaaacgtccg gttaaagtga tgctcccccg cccctctatt cccaataaca ccacgcaccg
     7801 ccccgccacc cttcagcact tgcgtatcgg tgccgaccag agcgggaaaa tcaccgctat
     7861 ctcacatgaa agctggtctg gaaacctgcc cggcggcacg ccggaaacgg cggtacagca
     7921 aagcgaatta ctctacgccg gggcgaatcg tcataccggc ctgcggctcg ccacgcttga
     7981 tttgccggaa gggaacgcca tgcgtgcgcc cggcgaagcc cccggtctga tggcgctcga
     8041 aatcgcgatc gacgaactgg cggaaaaagc gggcatcgat cccgtcgagt ttcgcatcct
     8101 gaatgacact caggttgacc ccgccgaccc gacgcgctgc ttctctcgcc gtcagcttat
     8161 cgagtgcttg cgcaccggag cggataaatt tggctggaag cagcgcaacg ccacacccgg
     8221 acaggtgcgc gacggggagt ggctagtcgg ccacggtgtt gcggcgggct ttcgcaataa
     8281 tctgctggaa aaatcgggtg ctcgggttca cctcgaacaa aacggcaccg ttaccgtaga
     8341 aacggacatg accgacattg gcaccggcag ctacaccatt ctggcccaga cggcagcgga
     8401 aatgcttggc gtaccgctgg agcaggttgc ggttcacctc ggcgattcca gtttcccggt
     8461 ttctgcgggt tctggtggac aatggggcgc gaatacctcc acctccggcg tttacgccgc
     8521 ctgtatgaag cttcgcgaaa tgattgcctc ggcagtcggg tttgatcctg agcagtcgca
     8581 gtttgccgac ggcaagatta ccaacggtac ccgaagcgcc acgctacatg aagccaccgc
     8641 aggcggcaga ctgacagcgg aagagagcat tgaattcgga acactgagca aagagtacca
     8701 gcagtcgacc tttgccgggc attttgtgga ggtcggcgtg catagcgcga cgggagaagt
     8761 tcgggtccgg cgtatgctcg ctgtgtgtgc tgcaggacgc atcctgaatc cgaaaactgc
     8821 gcgcagccag gtcattggcg caatgactat gggcatgggc gcggcactga tggaggagct
     8881 ggcggtggat gaccgtttgg gctacttcgt taatcacgat atggcggggt atgaggtgcc
     8941 ggttcatgcg gatatcccaa aacaggaggt gattttcctg gatgataccg accccatatc
     9001 ctccccgatg aaggccaaag gtgtcggtga gctgggcctg tgcggcgtga gcgcggctat
     9061 cgccaacgcg gtgtataacg ccaccggtat tcgggtacgg gattatccca tcactctgga
     9121 taagctgctc gataagctgc cggatgtggt ttaaggagga acaatgtcat acccgctttt
     9181 tgacaaagac gaacactggc ataagccaga gcaggcgttt ctcaccgatg accaccggac
     9241 cattctgcgc ttcgccgtag aggcgctaat gtccggtaaa ggagcggtgc tggtgacgct
     9301 ggtggagata cgcggcggcg cggcgcgccc gctcggggcg cagatggtgg tgcgcgaaga
     9361 tggtcgttac tgcggttttg tctctggcgg ctgcgtggag gccgctgccg cttttgaagc
     9421 gctggagatg atgggctcag gccgcgatcg cgaaattcgc tatggcgaag gttcgccgtg
     9481 gtttgacatc gttctgccct gcggcggtgg gatcacgctg acgctccata aactacgctc
     9541 ggcacagcct ctgctcgccg tgctgaaccg cctggaacag agaaaaccgg tggggctgcg
     9601 ctacgatccg caagcacaat cgctggtgtg cctgcccacg caaacccgga cgggctggaa
     9661 tctcaatggc tttgaggtgg ggttcaggcc atgcgtcagg ctgatgattt acggacgttc
     9721 tcttgaggcg caggcaaccg cgagtcttgc agcagccaca ggctatgaca gccatatctt
     9781 cgatcttttt ccggcctcag ccagcgctca gatcgatacc gatacggcgg tcattttgct
     9841 gtgccatgat ctcaaccggg agctgccagt gttgcaggcc gcgcgagaag caaaaccctt
     9901 ttatctcggc gcattgggca gctatcgaac ccacacgtta cgtctgcaaa agctccacga
     9961 gctgggatgg tccagggagg aaacaacgca aatccgggca cccgtcggga tattccccaa
    10021 agcccgggat gcgcatactc tggcactctc cgtgctggca gaagtcgcct ctgtacgtct
    10081 ccatcaggag gaggattcat gcctgccccc gtcgtcctga tccttgcggc cgggcgtgga
    10141 gagcgctttc tcgcctccgg gggaaatacc cataagtgta tcggctggcg tcagtccccg
    10201 gaggttgcgc cttatcgctg gccatttgaa gaaaacggga gaactttcga ccttgcgatt
    10261 gaaccgcaga ttacgactaa tgatctgcgt ctgatgttga ggctggctct tgccggcgga
    10321 ggaataacaa ttgccactca ggaaactttc aggccatata ttgaaagcgg taagcttgta
    10381 tcgctgcttg atgactttct tccacaattt ccgggcttct atctgtattt cccacagcgt
    10441 cgcaatattg caccaaagct ccgcgccctg attgactacg tcaaagaatg gcggcagcaa
    10501 ttggcttaaa tgtctgcacc tgcactgcct gatgtcagaa cagtattttg atgaattgcc
    10561 aaggttacaa tggcacaaat acggcacagg aggaaacgtg gtgtatttaa atatggggta
    10621 actctttgat tttaatggtg cgataatagg attcaaacaa gtaaggcatg ccattgattc
    10681 tacatgggaa tgtttcattt caacttttat atacccccaa aaataccccc attaatctag
    10741 ttgtcttgtc tgcgggaaat caacctgaac tttagactaa cgtggattcc atatgccatc
    10801 ctaaggaaac acattcgcaa atagtaatac ttggttacta tattcatttg tattattgcc
    10861 acgtcaacta ttagctctat tgaaaagagc aactctaaga aaaacataaa caatagtgaa
    10921 gttcgagaca aaataatatg aaaagaattg acattttcaa tcaaatcaat aaattgctct
    10981 ataacttaga taaatatact ttcatttttc tggttagact acatgacaag caatacagca
    11041 agaaccatac ttatggacat ggttgacacc aaaataacca ccatcaaagc taaatgcaga
    11101 agaaataagc gtttttttca attttttaca gctggttcta taattttaag tgcatcgatt
    11161 accgttgtag ttggtttaga atggcctaat catgctgcta ttcaaaagaa tattgcactt
    11221 ataatgggtg tatcattaac tctcattaat ggttgggtag ctatttttga ttttaaaaaa
    11281 ctttggatga gacaaaaaaa tacacttttt ggtttatatc ttatagataa cgaattaaaa
    11341 atcctcactg atagcgatga agataagttg agagttaaag aacttttcaa tgcttatcaa
    11401 gcagtttggg aaaaagacgg cagtgagtgg gcaaatattt tcagttccga cattgaatca
    11461 tcgaaaataa cacaaaatat caaagagttg caatcatgaa cttcgtgcat ttaaaagttg
    11521 ataaaatagc tattcatcag atctttccaa gaggtgaaga tgggaaggaa gtattaccgg
    11581 gcaaaggcac ggagttaata aattttgatg aagatgcttt gagcgatttt aaacaaagaa
    11641 tttataactc tcttgggcat gattcttctg ctgtggaaat ggtgataaca aacgaaaaga
    11701 cagaaagcac tccgttttac gtaaatattc tacatggttg taatgatgta gaatttataa
    11761 ataacagtta tgaaattgct aaaaatttat caaaagcaca aaaacgtaga ggcatgtccg
    11821 gaggtatact tgttgttttc agcgccacct atcaatataa caagcttcct tttgtaggca
    11881 ttatcaaagc tgacttatac agtggatacg aaaaatggca agataaaaaa acaggcatta
    11941 tttctttaaa acatgtaaaa gagctactac ttacgccttc aaccaagctt tataagtctg
    12001 ccggattttt taaacgtgaa aacgtaaaaa atgatagcac cttaagtgaa caatgggccg
    12061 tacatatttc tgattatcag attgataaat ctgacggtaa agctgctgct cagtattttt
    12121 atcaaacttt cctcggttgt gattacccag caaccagtgc cagaacaaca aaacgttatt
    12181 ttgaaatagc atgtgatttt ataaatcaaa tggatattga tgaagaagag cgaacccact
    12241 tacacaacgt cttatacgca gacctaaaag caggtaaatc acaaaaagtt gatcctatgg
    12301 catttgctgg ctcatatatg tcaacagcag atgtagataa ttttaggaac tatttagacg
    12361 attatgattt tccggttggt ccattcataa aagatacgca gtacatctct agcaaattaa
    12421 agaataggcg tttaaaattt agtaaaaaca ttcgaatcag cgcaccatca gaaatctttg
    12481 aagagtttgt ttctattgaa actgtagagg gtgaagcagg tcaagatggt tatagaccaa
    12541 cttggacaaa aattcttgtt aaagacagaa tagtagatca ataatgactg agaccgaatt
    12601 cctcaagcaa tggcattccg agaaggcgat gtatggcgct tggggtcagt atattgttag
    12661 ttctatatca gaagcgctta tcaaatctct taaggtagat cttaagaatt atcttaaaat
    12721 accagtaaat cacagagtta aagatgatgg gtctttagtt gataaagcct tatatcgtaa
    12781 taaagcgtac aaaaatcctt ataatgatat tgaagataag gtaggtgttc gctttgtcgt
    12841 aatgctccaa actgacgttg aaaaagtatg cgaggttatt aaacaagttg ccgttcaaga
    12901 aggttgggat gctacgcagt gtagaaacta taatgaggag cgtagagaat cgccaatgct
    12961 cttcacctat caatctcatc attttatcat ccgaaataaa agagcattta cacatggagg
    13021 tattctcatt catgaaaaca ccccttgtga ggttcaggta cggtctctgc ttcagcatgc
    13081 atatgctgaa ttaacccatg atgccattta caagaaaaaa acaattatag aacctgatgt
    13141 tgttcgtacc gttgctaaaa caatggcttt tatcgaaacg gcagatgaat tctttcaaaa
    13201 ggttgtggat agaactgagt cggaaaatat actcaaaaat gagtcatttt tggatactct
    13261 ctttgaacaa ataacaggcg tacaacctat aaaacaaaac tc
//
LOCUS       DAPOAV010000101        13231 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.101, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000101 DAPOAV010000000
VERSION     DAPOAV010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13231
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.101"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(174..386)
                     /gene="cspH"
                     /locus_tag="RN951_003693"
     CDS             complement(174..386)
                     /gene="cspH"
                     /locus_tag="RN951_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspH"
                     /protein_id="HDX2528635.1"
                     /translation="MSRKMTGIVKTFDRKSGKGFIIPSDGRKEVQVHISAFTPRDAEV
                     LIPGLRVEFCRVNGLRGPTAANVYLS"
     gene            672..884
                     /gene="cspG"
                     /locus_tag="RN951_003694"
     CDS             672..884
                     /gene="cspG"
                     /locus_tag="RN951_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock protein CspG"
                     /protein_id="HDX2528636.1"
                     /translation="MSNKMTGLVKWFNADKGFGFITPDDGSKDVFVHFTAIQSNEFRT
                     LNENQKVEFSIEQGQRGPAAANVVTL"
     gene            895..1083
                     /locus_tag="RN951_003695"
     CDS             895..1083
                     /locus_tag="RN951_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDX2528637.1"
                     /translation="MTQHLHFRCPCCHGSQYRTSAFDVTERNPLGAKCIFCKSTMITF
                     DNVALQIRTDHAPLDFTK"
     gene            1058..1288
                     /gene="ymcE"
                     /locus_tag="RN951_003696"
     CDS             1058..1288
                     /gene="ymcE"
                     /locus_tag="RN951_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YmcE"
                     /protein_id="HDX2528638.1"
                     /translation="MRRWISQNNIRLPRGAFFISALFFFNAVCIVSDNLLIIESFGEM
                     AYNISYLTRVPGTNTLLACCCLLRPEEVNSEY"
     gene            1278..1451
                     /locus_tag="RN951_003697"
     CDS             1278..1451
                     /locus_tag="RN951_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin, GnsA/GnsB family"
                     /protein_id="HDX2528639.1"
                     /translation="MNIEELKKQAETEIADFIAQKIAELNKNTGKEVSEIRFTAREKM
                     TGLESYDVKIKIM"
     gene            complement(1500..2573)
                     /locus_tag="RN951_003698"
     CDS             complement(1500..2573)
                     /locus_tag="RN951_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDX2528640.1"
                     /translation="MAENKRTRWQRRPGTTGGKLPWNDWRNATTWRKATQLLLLAMNI
                     YIAITFWYWVRYYETASSTTFVARPGGIEGWLPIAGLMNLKYSLVTGQLPSVHAAAML
                     LLVAFIVISLLLKKAFCSWLCPVGTLSELIGDLGNKLFGRQCVLPRWLDIPLRGVKYL
                     LLSFFIYIALLMPAQAIHYFMLSPYSVVMDVKMLDFFRHMGTATLISVTVLLIASLFI
                     RHAWCRYLCPYGALMGVVSLLSPFKIRRNAESCIDCGKCAKNCPSRIPVDKLIQVRTV
                     ECTGCMTCVESCPVASTLTFSLQKPAANKKAFALSGWLMTLLVLGIMFAVIGYAMYAG
                     VWQSPVPEELYRRLIPQAPMIGH"
     gene            complement(2645..5389)
                     /gene="torS"
                     /locus_tag="RN951_003699"
     CDS             complement(2645..5389)
                     /gene="torS"
                     /locus_tag="RN951_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415513.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system sensor histidine
                     kinase/response regulator TorS"
                     /protein_id="HDX2528641.1"
                     /translation="MNLTLTRRLWMGFALMALLTLTSTLVGWYNLRFISQVEKDNTQA
                     LIPTMNMARQLSEASAWELFAAQNLTSADNEKMWQAQGRMLTAQSLKINALLQALREQ
                     GFDTTAIEQQEQEISRSLRQQGELVGQRLQLRQQQQQLSQQIVAAADEIARLAQGQAN
                     NATTSAGATQAGIYDLIEQDQRQAAESALDRLIDIDLEYVNQMNELRLSALRVQQMVM
                     NLGLEQIQKNAPTLEKQLNNAVKILQRRQIRIEDPGVRAQVATTLTTVSQYSDLLALY
                     QQDSEISNHLQTLAQNNIAQFAQFSSEVSQLVDTIELRNQHGLAHLEKASARGQYSLL
                     LLGMVSLCALILILWRVVYRSVTRPLAEQTQALQRLLDGDIDSPFPETAGVRELDTIG
                     RLMDAFRSNVHALNRHREQLAAQVKARTAELQELVIEHRQARAEAEKASQAKSAFLAA
                     MSHEIRTPLYGILGTAQLLADNPALNAQRDDLRAITDSGESLLTILNDILDYSAIEAG
                     GKNVSVSDEPFEPRPLLESTLQLMSGRVKGRPIRLATAIADDMPCALMGDSRRIRQVI
                     TNLLSNALRFTDEGYIILRSRTDGEQWLVEVEDSGCGIDPAKLAEIFQPFVQVSGKRG
                     GTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLPLRVATAPVPKTVNQAVRLDGL
                     RLLLIEDNPLTQRITIEMLKTSGAQIVAVGNAAQALETLQNSEPFAAALVDFDLPDID
                     GITLARQLAQQYPSLVLIGFSAHVIDETLRQRTSSLFRGIIPKPVPREVLGQLLAHYL
                     QLQVNNDQSLDVSQLNEDAQLMGTEKIHEWLVLFTQHALPLLDEIDIARASQDSEKIK
                     RAAHQLKSSCSSLGMHIASQLCAQLEQQPLSAPLPHEEITRSVAALEAWLHKKDLNAI
                     "
     gene            5472..6500
                     /gene="torT"
                     /locus_tag="RN951_003700"
     CDS             5472..6500
                     /gene="torT"
                     /locus_tag="RN951_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system periplasmic protein TorT"
                     /protein_id="HDX2528642.1"
                     /translation="MRVLLFLLLSLFMLPAFSADNLLRWHDAQHFTVQASTPLKAKRA
                     WKLCALYPSLKDSYWLSLNYGMQEAARRYGVDLKVLEAGGYSQLATQQAQIDQCKQWG
                     AEAILLGSSTTSFPDLQKQVASLPVIELVNAIDAPQVKSRVGVPWFQMGYQPGRYLVQ
                     WAHGKPLNVLLMPGPDNAGGSKEMVEGFRAAIAGSPVRIVDIALGDNDIEIQRNLLQE
                     MLERHPEIDVVAGTAIAAEAAMGEGRNLKTPLTVVSFYLSHQVYRGLKRGRVIMAASD
                     QMVWQGELAVEQAIRQLQGQSVSDNVSPPILVLTPKNADREHIRRSLSPGGFRPVYFY
                     QHTSAAKK"
     gene            complement(6473..7165)
                     /gene="torR"
                     /locus_tag="RN951_003701"
     CDS             complement(6473..7165)
                     /gene="torR"
                     /locus_tag="RN951_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator TorR"
                     /protein_id="HDX2528643.1"
                     /translation="MPHHIVIVEDEPVTQARLQSYFTQEGYTVSVTASGAGLREIMQN
                     QSVDLILLDINLPDENGLMLTRALRERSTVGIILVTGRSDRIDRIVGLEMGADDYVTK
                     PLELRELVVRVKNLLWRIDLARQAQPHTQDNCYRFAGYCLNVSRHTLERDGEPIKLTR
                     AEYEMLVAFVTNPGEILSRERLLRMLSARRVENPDLRTVDVLIRRLRHKLSADLLVTQ
                     HGEGYFLAADVC"
     gene            7295..8467
                     /gene="torC"
                     /locus_tag="RN951_003702"
     CDS             7295..8467
                     /gene="torC"
                     /locus_tag="RN951_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentaheme c-type cytochrome TorC"
                     /protein_id="HDX2528644.1"
                     /translation="MRKLWNALRRPSARWSVLALVAIGIVIGIALIVLPHVGIKVTST
                     TEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQ
                     TFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQM
                     KVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAK
                     GDKEASGSLLPASEVKVLKRDGDWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGD
                     VQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHG
                     APEIAHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK"
     gene            8467..11013
                     /gene="torA"
                     /locus_tag="RN951_003703"
     CDS             8467..11013
                     /gene="torA"
                     /locus_tag="RN951_003703"
                     /EC_number="1.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethylamine-N-oxide reductase TorA"
                     /protein_id="HDX2528645.1"
                     /translation="MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAAT
                     DAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRY
                     PMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGW
                     QSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLV
                     LQNSKTIVLWGSDLLKNQQANWWCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTH
                     EYLGREHVKHIAVNPQTDVPLQLALAHTLYSENLYDKNFLANYCVGFEQFLPYLLGEK
                     DGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLA
                     AMLGQIGLPGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIP
                     IARFIDAILEPGKVINWNGKSVKLPPLKMCIFAGTNPFHRHQQINRIIEGLRKLETVI
                     AIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEARNDFDI
                     FRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFD
                     HPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGG
                     PGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGKEPVFINPQDASARGIRNGDV
                     VRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIG
                     TSQLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEYVPASQVKS"
     gene            11010..11609
                     /gene="torD"
                     /locus_tag="RN951_003704"
     CDS             11010..11609
                     /gene="torD"
                     /locus_tag="RN951_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone TorD"
                     /protein_id="HDX2528646.1"
                     /translation="MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLL
                     KSEPPLTAAVNELENRIATLTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQ
                     EIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGERTVPARRIDSLRQKTLTA
                     LWQWLPEFVARCRQYDSFGFYAALSQLLLVLVECDHQNR"
     gene            complement(11761..12066)
                     /gene="cbpM"
                     /locus_tag="RN951_003705"
     CDS             complement(11761..12066)
                     /gene="cbpM"
                     /locus_tag="RN951_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone modulator CbpM"
                     /protein_id="HDX2528647.1"
                     /translation="MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWV
                     FDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP"
     gene            complement(12066..12986)
                     /gene="cbpA"
                     /locus_tag="RN951_003706"
     CDS             complement(12066..12986)
                     /gene="cbpA"
                     /locus_tag="RN951_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curved DNA-binding protein"
                     /protein_id="HDX2528648.1"
                     /translation="MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEA
                     RFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHGDGQSFNAEDFDDIFSSIF
                     GQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTL
                     NVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVS
                     PWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMP
                     PKPDENTAALWQQLADAQSSFDPRKDWGKA"
BASE COUNT         3229 a         3355 c         3447 g         3200 t
ORIGIN      
        1 tttcaagtgg tactataact ggctgttaaa tggcatttat aactattagg tgcagagata
       61 ttcgcttaaa tggattagtt tctttgtgga aaagtaactg atgttataat gtatgatgtt
      121 gactattgca ctattccaat aaaaccagtc agctttaaac aagcagcgtc atattaagag
      181 agataaacat ttgccgctgt tggtcctcgc aggccattta cgcggcaaaa ttccacacgt
      241 aatcctggta taagcacttc tgcgtcgcgg ggagtgaatg cggaaatatg gacctgaact
      301 tctttacgac cgtcggaggg gataatgaat cctttgccgc ttttgcgatc aaaggttttg
      361 acaattcctg tcattttacg ggacaaacaa attccttact gaaaatactg cgctgcacta
      421 tacggggtta ataaaataaa gccagcgata tttaagaccg ccggacggct aaaataaaat
      481 ttgcttaatc tcaattatca tgcgttaata gctgcgtcgg tttgaaagac agacagcata
      541 caaagtagtt tactaaagca gttctcatta tcaggcatta tccccttctt ttgagtctct
      601 ctcctgaaca ctaagtagtt tctgtattaa agccctgttt gccgaaaggc ccaaaatgaa
      661 ggaagtaaaa tatgtctaat aaaatgactg gtttagtaaa atggtttaac gcagataaag
      721 gttttggctt tatcactcct gatgatggca gcaaagacgt tttcgtccat ttcaccgcca
      781 tccagagcaa tgaattccgc acgctgaacg aaaatcagaa agttgaattt tctattgagc
      841 aggggcaacg tggccccgcg gcagcgaacg ttgttacgct ctaaggttgc cattattact
      901 caacatctcc atttccgctg tccatgttgt catggttcac agtaccgcac atcggcattc
      961 gatgtgacgg agcgaaaccc tttgggcgct aagtgtattt tttgtaaatc gacgatgatc
     1021 acctttgata acgtcgcgct gcaaatacgc actgaccatg cgccgctgga tttcacaaaa
     1081 taatatcagg ctccctcgtg gagccttttt tatatctgcc ttatttttct tcaacgctgt
     1141 atgtatagta agcgataacc tgttgattat tgaatctttc ggggagatgg cttataacat
     1201 ttcttacctg accagggtac cgggaaccaa caccttactg gcgtgttgct gtcttttaag
     1261 accagaagag gttaacagtg aatattgaag agttaaaaaa acaagccgaa acggaaatcg
     1321 ccgactttat cgcgcaaaaa atcgccgagc tgaacaagaa tacagggaaa gaagtctctg
     1381 aaattcgctt caccgcacga gaaaaaatga ccgggcttga aagttatgat gtcaaaatca
     1441 aaataatgtg attttgtgaa catcaccccg tgcgaggtga tgttccgctt gttgctaatt
     1501 tagtgaccaa tcattggcgc ttgtggaatt aagcgtcggt acaattcctc cggcaccggg
     1561 ctttgccata ctcccgcata cattgcgtaa ccaatcaccg caaacataat ccccagaacc
     1621 agtagcgtca ttaaccagcc agacaacgca aaggcttttt tatttgccgc aggtttttgc
     1681 agtgaaaagg tcaatgttga ggctaccgga catgactcta cgcaagtcat acagccggta
     1741 cattccactg ttcgtacctg aattaattta tcgaccggga tccgtgatgg gcaatttttt
     1801 gcgcatttgc cacagtcgat acaactttcg gcattgcgac gaatcttaaa cggcgacaat
     1861 agcgaaacca cgcccatcag cgcgccatat gggcaaagat aacgacacca ggcatggcga
     1921 ataaacaggc tggcaatcag caaaacggtc acgctgatta atgtcgcggt ccccatatga
     1981 cgaaagaaat cgagcatttt aacgtccatc accacgctgt agggcgacaa cataaaatag
     2041 tgaatcgcct gagcgggcat caataacgcg atatagataa aaaaactcaa cagcaaatac
     2101 ttcacgccgc gcagaggaat atccagccag cggggaagga cacattgccg accaaacagt
     2161 ttgttaccga gatcgccgat taattcagaa agcgtaccaa ccgggcataa ccatgagcaa
     2221 aaggcctttt tgagtaatag actgatgacg ataaaagcga ccaataacag catcgcggcg
     2281 gcgtggacgg acggtaactg acctgttaca aggctatatt tcagattcat cagcccggca
     2341 atcggtagcc agccttcgat acctcccggt ctggcgacaa atgtcgtgct acttgccgtt
     2401 tcgtaatagc gcacccaata ccagaacgtg atggcaatat aaatattcat tgccaacagt
     2461 aataattgcg tcgctttacg ccaggtcgtg gcattacgcc agtcattcca cggtaatttg
     2521 ccgcccgtcg tgcctggccg ccgctgccag cgggttcttt tattctctgc catgattttg
     2581 ccagtccgtt aagttgtata ccaaatgcca ctattctagt tgttcttaac tggctgatat
     2641 tgattcaaat cgcgttcagg tctttcttat gcaaccatgc ttccagagcg gcaacactgc
     2701 gtgtaatttc ttcgtgtgga aggggggcag ataatggctg ctgctccagt tgtgcgcata
     2761 gctggctggc gatatgcatt cccagactcg agcaactgct ttttagctga tgcgcggcac
     2821 gctttatttt ctcgctatcc tgactggcgc gggcaatgtc gatttcatcg agaagcggca
     2881 gggcatgttg tgtaaataat accagccatt cgtggatctt ctccgtcccc attaactgag
     2941 catcttcatt gagttgcgat acatccagcg attgatcatt attgacttgc agttggagat
     3001 agtgcgccag taactgaccg agcacttcac gcggcaccgg tttagggata atcccgcgga
     3061 ataatgaact ggtacgctgg cgcagcgttt cgtcaatgac atgggcgcta aagccaatca
     3121 aaaccagcga cggatattgc tgtgccagtt gtcgggcaag cgtaatgccg tcgatatccg
     3181 gcagatcaaa atccaccagt gcggcagcaa acggttcgct attttgcagt gtctctaaag
     3241 cctgcgcggc attgccaaca gcaacaatct gcgcaccact ggttttcagc atctcaatgg
     3301 taattcgctg ggttagcggg ttatcttcaa ttaacagcaa acgtaaaccg tcaagacgca
     3361 ccgcctgatt gactgttttt ggcacgggtg ccgtggcaac acgtaacggc aagcgtaaac
     3421 aaaaacagct tccaacctcc ggcgtgctgg tggcgctcag ttcgccgccc atcgcctggg
     3481 ccagacggct actgatagtc agtcccagcc cggtgccgcc gcgtttgccg cttacctgca
     3541 caaatggctg gaagatttct gccagtttcg cgggatcaat accgcagccg ctgtcttcca
     3601 cttcgaccag ccattgctcg ccatcagtgc gactacgcag gataatgtac ccttcgtcag
     3661 taaaacgcag ggcgttgctc aacaggttgg ttataacctg acgaatacgt cgtgaatcgc
     3721 ccattaacgc gcacggcata tcatcggcaa ttgccgttgc caggcgaatc gggcgacctt
     3781 tcacccgtcc gctcattaat tgcagggtac tttccagcag cgggcgcggt tcaaagggct
     3841 catcgctgac cgaaacattc ttgccacctg cttcgatagc ggaataatcg agaatatcgt
     3901 tgaggatggt cagcaacgat tcaccagagt cagtaattgc ccgcaaatca tcacgctggg
     3961 cgttaagtgc ggggttatct gccagcagtt gagcagtgcc gagaataccg tacagcggtg
     4021 tgcggatctc atggctcatc gccgccagaa acgccgattt tgcctggctg gctttttctg
     4081 cttccgcccg tgcctgtcgg tgttctatca ccagttcctg caattcagct gtacgcgctt
     4141 tgacctgcgc cgccagctgt tcgcggtggc gattcagtgc atgaacattg ctgcgaaacg
     4201 catccatcag ccgcccgatg gtatccagct cccgtacgcc agcggtttcc gggaaagggg
     4261 agtcaatatc accgtccagc agccgttgca gcgcctgcgt ttgttcggca agtggacgcg
     4321 tgactgagcg ataaaccacg cgccagagga tcagaatcag tgcgcaaagt gaaaccatcc
     4381 ccagcaataa caggctgtat tgcccgcgtg cactcgcttt ttccagatgc gccagtccgt
     4441 gctgattacg cagctcaatg gtgtcgacca gctgactgac ttcgctacta aactgcgcga
     4501 actgggcgat gttattttgt gcgagagttt gtaggtgatt gctgatttca ctgtcctgct
     4561 gatacagcgc cagcaaatcg ctatattggc taacggtagt taacgttgtt gcgacctgcg
     4621 cacgaacacc cggatcttca atgcgtattt gccgacgttg cagaattttc accgcattat
     4681 tgagctgctt ttccagcgtt ggtgcatttt tctggatctg ctccagcccc agattcatca
     4741 ccatttgctg cacccgcaga gcgctaaggc gcagttcatt catctggtta acatactcaa
     4801 gatcgatatc aatcagccga tcgagtgcac tttcagcagc ctgacgctga tcttgttcga
     4861 tcaaatcgta aatcccggcc tgggtcgctc cagcggaagt tgtcgcatta ttcgcctgac
     4921 cttgcgccag gcgtgcgatc tcatcggcgg cagcgactat ctgctgactg agttgctgtt
     4981 gttgctggcg cagttgcaaa cgctgcccca ccagttcccc ttgctgacgt aacgaacggg
     5041 agatctcctg ctcctgttgt tcaatagcgg tggtatcaaa accttgttcc cgtaacgctt
     5101 gcagcaacgc attaatcttc aggctttgtg cggtgagcat tcgcccctgc gcctgccaca
     5161 tcttttcgtt atcggcactg gtcaggttct gcgcggcgaa aagttcccag gcgctggctt
     5221 cgctcaactg gcgcgccata ttcatggtag gaatcaatgc ctgagtgttg tctttttcca
     5281 cctggctgat aaagcgcagg ttgtaccatc ccaccagggt actggtcagg gttaacagcg
     5341 ccatcagggc aaagcccatc cagagtcttc gggtcagggt taaattcacg gtcggtgcac
     5401 tttaggtgaa aaaggttgag tcgcaaagcg gaatgcatct agcataaagc cttattattg
     5461 atgaggctat catgcgcgta ctgctatttt tacttctttc ccttttcatg ttgccggcat
     5521 tttcggctga taacctgttg cgctggcatg atgcgcagca tttcacggtg caagcctcta
     5581 cgccgcttaa agccaaacgc gcatggaaac tgtgcgcgct ttatcccagc ctgaaagatt
     5641 catattggtt atcgttgaac tatggtatgc aggaggctgc tcgccgctac ggtgtggatt
     5701 taaaagtgct ggaggcaggc ggctacagcc agttggctac ccagcaagca caaatcgacc
     5761 agtgtaaaca gtggggcgca gaggccattt tgctcggtag tagcacgacc tcatttcccg
     5821 acctgcaaaa gcaggtagca agtctgccgg tgatcgaact ggtaaatgct attgatgctc
     5881 cccaggtgaa aagccgcgtt ggtgtgccct ggtttcagat gggctatcaa ccggggcgat
     5941 atctggtgca atgggcgcac ggtaaaccac tgaatgtgct gttgatgccc ggacccgata
     6001 acgccggggg cagtaaggag atggtcgagg gttttcgcgc agccattgcc ggaagcccgg
     6061 tgcgtattgt tgatattgcg cttggtgata acgatattga aatccagcgt aacctgttgc
     6121 aggagatgct ggaacgccat ccagaaatcg acgtcgttgc cggaacggcc attgcggcag
     6181 aggcggcaat gggggaaggg cgtaacctga aaacgccgct taccgtggtg tcgttttatc
     6241 tttcacatca ggtgtatcgc gggctgaagc ggggaagagt gattatggct gccagcgatc
     6301 aaatggtctg gcagggggaa ctggcggttg agcaggccat caggcaatta caggggcaat
     6361 cggtttctga taatgtcagc ccaccgattt tagttctgac gccgaaaaat gccgaccgtg
     6421 aacatattcg ccgctcgctg tcaccagggg gatttcgtcc ggtctatttt tatcagcaca
     6481 catcagcggc taagaaataa ccttcaccat gttgcgtcac cagtaaatcc gcgctgagtt
     6541 tatgacgtaa acgacgaatt aacacatcga cggtgcgcag gtcagggttt tccacccgac
     6601 gcgcagaaag catacgtagc agacgttcac ggctgagaat ttcgcccgga ttcgtcacaa
     6661 atgccaccaa catttcatac tctgcgcggg tcagtttaat cggctcgcca tcccgctcca
     6721 gcgtatggcg cgacacattc aggcaataac cggcaaagcg atagcagttg tcctgagtgt
     6781 gcggttgagc ttgtcgcgcg aggtcgattc gccagagcag atttttcacc cgtactacca
     6841 gttcgcgcag ttccagcggt ttggtgacgt aatcgtctgc gcccatttcc agcccaacaa
     6901 tacggtcaat ccgatcgctg cgtccggtaa ccagaataat ccccaccgtt gagcgttctc
     6961 gcagggcgcg ggttaacatc aggccatttt catcgggtaa gttgatatcc agcagaatta
     7021 aatctaccga ctgattctgc ataatttccc gtagcccggc accgctcgcc gtaacggaaa
     7081 cggtataccc ctcctgagtg aagtaggatt gtaatcgcgc ctgggtaacc ggctcatctt
     7141 caacaataac aatgtgatgt ggcatcagag ggttttactc attctgttca tatctgttca
     7201 tattctgccg taagccgttc atcctgacca gtgccgctgt tcatatttgc tcattaagat
     7261 cgcttcacta aaccataatt ctacaggggt tattatgcgg aaactctgga acgcgctacg
     7321 ccgacccagt gctcgttggt cggtactggc gctggtcgca attgggattg tgattggcat
     7381 tgcgctgatt gtattgccac acgttgggat caaagtcacc agcacaaccg aattttgtgt
     7441 cagttgccac agtatgcaac cggtgtatga agaatataaa cagtcggtgc atttccagaa
     7501 cgcctccggc gtgcgagctg aatgccatga ctgtcatatc ccgccggata ttccaggcat
     7561 ggtgaagcgc aaactggaag cgagcaatga tatctaccag acctttattg ctcactccat
     7621 tgatacacct gaaaaattcg aagccaaacg cgcggaactt gccgagcgtg aatgggcgcg
     7681 aatgaaagaa aacaactcgg caacctgccg ctcctgccat aactacgatg cgatggatca
     7741 tgcgaagcag catcctgaag cagcacgtca gatgaaggtg gcagcgaaag ataatcaatc
     7801 ctgcatcgac tgtcataaag gtattgccca ccagttaccg gatatgagta gcggcttccg
     7861 taagcagttc gatgagctgc gagccagtgc taatgacagt ggtgacacgc tgtactctat
     7921 tgatattaag ccaatttatg cggcgaaagg cgataaagaa gcctctggtt ctctgctgcc
     7981 tgcttcggaa gtgaaagtcc ttaaacgtga cggcgactgg ctgcaaattg aaattaccgg
     8041 ctggacggaa agcgccggac gtcagcgtgt actcacccaa ttcccaggta aacgcatctt
     8101 tgttgcctcg attcgtggtg atgtgcagca gcaggtaaaa acgctggaga aaaccaccgt
     8161 tgccgacacc aataccgagt ggagcaagtt gcaggccact gcgtggatga agaaaggcga
     8221 catggtgaac gatatcaaac cgatctgggc ttatgcggat tcgttgtaca acggcacctg
     8281 taaccagtgc cacggcgcac cggaaatcgc ccactttgac gctaacggtt ggatcggcac
     8341 gctcaacggc atgattggct ttaccagtct cgataaacgt gaagaacgca ccttgttgaa
     8401 atatctgcaa atgaatgcgt ctgacaccgc aggtaaggct cacggcgata agaaggaaga
     8461 aaaataatga acaataacga tctctttcag gcatcacgtc ggcgttttct ggcacaactc
     8521 ggcggcttaa ccgtcgccgg gatgctgggg ccgtcattgt taacgccgcg acgtgcgact
     8581 gcggcgcaag cggcgactga cgctgtcatc tcgaaagagg gcattcttac cgggtcgcac
     8641 tggggggcta tccgcgcgac ggtgaaggat ggtcgctttg tggcggcaaa accgttcgaa
     8701 ctggataaat atccgtcgaa aatgattgcc ggattgccgg atcacgtaca caacgcggcg
     8761 cgtattcgtt atccgatggt acgcgtggac tggctgcgta agcgccatct cagcgatacc
     8821 tcccagcgcg gtgataaccg ttttgtgcgc gtgagctggg atgaagccct cgacatgttc
     8881 tatgaagaac tggaacgcgt gcagaaaact cacgggccga gtgccttgct gaccgccagt
     8941 ggttggcaat cgacggggat gttccataac gcttcgggga tgctggcgaa agctattgcc
     9001 ttgcatggta atagcgttgg tacgggcgga gattactcta ccggtgctgc gcaggtgatc
     9061 ctgccgcgcg tagtcggttc gatggaagtg tatgaacagc aaacctcctg gccgctggta
     9121 ttgcagaaca gcaaaaccat tgtgctgtgg ggctccgatt tgctgaaaaa ccagcaagcg
     9181 aactggtggt gcccggatca cgatgtttat gaatattacg cgcagctaaa agcgaaagtc
     9241 gccgccggtg aaattgaggt catcagcatc gatccggttg tcacatccac ccatgagtat
     9301 ctggggcgcg agcatgtgaa gcacattgcg gttaacccgc aaactgacgt gccgctgcaa
     9361 ctggcgctgg cacatacgct gtacagtgaa aacctgtacg acaaaaactt ccttgctaac
     9421 tactgtgtgg gttttgagca gttcctgccg tatctgctgg gtgagaaaga cggtcagccg
     9481 aaagatgccg catgggctga aaaactgacc ggcattgatg ccgaaaccat tcgtgggctg
     9541 gcgcggcaga tggcggcgaa cagaacgcaa attattgctg gctggtgcgt gcagcgtatg
     9601 cagcacggtg aacagtgggc gtggatgatt gtggttctgg cggcgatgct ggggcaaatt
     9661 ggcctgccag gtggtggttt tggttttggc tggcactaca acggcgcagg cacgccgggg
     9721 cgtaaaggcg ttattctgag tggtttctcc ggctctacgt cgattccgcc tgttcacgac
     9781 aacagtgact acaaaggcta cagcagcact attccgattg cccgttttat cgatgcgatc
     9841 ctcgaaccgg ggaaagtgat caactggaac ggtaaatcgg taaaactgcc gccgctgaaa
     9901 atgtgtattt ttgccggaac taacccattc catcgccatc agcagatcaa ccgcattatt
     9961 gaaggcttgc gcaagctgga aacggttatc gccatagata accagtggac ctcaacctgc
    10021 cgctttgccg atatcgtact gcctgcgacc acgcagtttg agcgtaacga tctcgaccag
    10081 tacggcaatc actccaaccg tggcattatc gccatgaaac aggtggtgcc gccgcagttc
    10141 gaggcgcgca acgacttcga tattttccgc gagctgtgcc gtcgctttaa tcgcgaagaa
    10201 gcctttaccg aagggctgga cgaaatgggc tggctgaaac gcatctggca ggaaggtgta
    10261 cagcaaggca aaggacgcgg cgttcatctg ccagcgtttg atgacttctg gaataacaaa
    10321 gagtacgtcg agtttgacca tccgcagatg tttgttcgcc accaggcatt ccgcgaagat
    10381 ccggatctcg aaccgctggg cacgccgagt ggcctgattg agatctactc gaaaactatc
    10441 gccgatatga actacgacga ttgtcagggg catccgatgt ggtttgagaa aatcgaacgc
    10501 tcccacggtg ggcctggctc gcaaaagtat ccgttgcatc tgcaatctgt gcatccggat
    10561 ttccgacttc actcgcagtt atgtgagtcg gaaacgctgc gtcagcaata tacggtagcg
    10621 ggtaaagagc cagtattcat taacccgcag gatgccagcg cgcgcggtat tcgtaacggt
    10681 gatgtggtac gcgtctttaa cgctcgcggt caggtgttgg caggggcagt ggtttctgac
    10741 cgctatgcac ccggcgtggc acgaattcac gaaggggcat ggtacgatcc agataaaggc
    10801 ggcgagcctg gtgcgctgtg caaatacggt aaccccaacg tgttgaccat cgacatcggt
    10861 acatcgcagc tggcgcaggc gaccagtgcg cacactacgc tggtggaaat tgagaagtac
    10921 aacggaacag tggagcaggt gacggcgttt aacggccccg tggagatggt ggcgcagtgc
    10981 gaatatgttc ccgcgtcgca ggtgaaatca tgaccacgct gacagcacaa cagattgcct
    11041 gtgtttacgc ctggctagcg cagttgttct cccgtgagct ggacgatgaa caactgacgc
    11101 aaatcgccag tgcgcagatg gctgaatggt tttcgttgct gaaaagcgaa ccgccgctca
    11161 ctgcggcggt gaacgagctg gaaaaccgta ttgccacgct gacagtacgt gacgatgccc
    11221 gtctggaact ggccgcggac ttttgcggcc tgtttctgat gaccgacaaa caagcggcgc
    11281 tgccgtatgc atcggcctac aaacaggacg agcaagagat taaacgcttg ttagttgagg
    11341 cagggatgga aaccagcggc aatttcaacg aaccggcaga tcatctggcg atctatctcg
    11401 aattgctcag ccatctgcat ttttcgctgg gagagaggac cgttcctgcg cgaagaatcg
    11461 acagtttgcg gcaaaaaaca ctgacggcgc tgtggcaatg gttaccagag tttgttgcgc
    11521 gttgtcgtca gtatgacagc tttggttttt acgcggcact aagccagtta ttgctggtgt
    11581 tagtggagtg cgaccaccaa aacagataac gtcgtttgtg cgcctgaaaa gacgcgttta
    11641 gcgtcgcatc aggcattatg gcgcagttgc cggatgcggc gtgaacgtct tatccggccc
    11701 acaggaactg taatctttgt agaccggtta agatgcgtca tcgcatccgg caaacacaca
    11761 tcacggatga gctacaaacc gggaaagccg ctggcgcagc aggcggtttt cctgcttcag
    11821 gtgcgcaata tcatccatta acgtcagcgc caccgcgatc cccggccagt ccagagccag
    11881 ttcatgacgc aggcgtaccg cgcgttgcac cacaatggcg gcatggtcgt caaataccca
    11941 ggttgtttcc tggatctcac gcggttcaac cacccccaaa ccgacaattt cattcaactc
    12001 ctcttcagag atgccggtat gcaggcaaaa ttcggtaata gtaaaagtca ccgtaacatt
    12061 agccattatg ctttccccca atctttacgt ggatcaaaag acgactgggc gtctgccagt
    12121 tgctgccaca gcgcggcagt gttttcatcc ggtttcggcg gcatcacgat tttcagtacc
    12181 gcatacagat cgccggtctg ttttttgctc accagacctt tgcctttaac gcgcaatcgt
    12241 tgcccggcct ggctgcctgg cgggatagtc agcaaaatgc tttctttcag tgttggaacg
    12301 gtgactttag cacccagcgc cgcttcccac gggctaaccg gcaccacaat ttccagatcc
    12361 tggccgacaa tatcaaacag cggatgtggc gcaatatgaa tcaccagcca caaatcgcca
    12421 tttggaccgc cgttttcgcc cggcgtcccc tggcctttca gacggatgcg ttgaccattg
    12481 ccgacgcccg ccgggatctt cacattcagc gttttcggaa tttcctgttc gatcatgcca
    12541 aaggcgttat aaaccggcag gttatagctg atggtacgct tatgctcagt aagcgtttct
    12601 tcgaggaata ccgccacttc gatttcaata tcgtggccgc gtgtggcggg gcgttgacgg
    12661 ctctggcggg catgctgacc gaaaattgac gagaagatat cgtcaaaatc ttcggcgtta
    12721 aaactctgac cgtcgccatg gtggaactga cggttaaatt gcggatcgtt gcgatgttgc
    12781 cacatctgat catactcagc gcgacgttgt tcatcactta acacttccca ggcttcagcg
    12841 acctctttga agcgggcttc ggcatccggt tctttgctga catcaggatg gtatttgcgg
    12901 gcaagtcgac gataggcggt cttgattgtc ttgagatcgt ccgtcggttt cacgcccatg
    12961 atggcgtaat aatcctttaa ttccatagcg ttatctcgcg taaatcaaca caaattgaag
    13021 gaacccctgt aaggtaactc ctataagtgt agggtaatcc tcaaaatttc atatgccaac
    13081 acagaatatg ttattgaaat catcgcggag aggaggtcgc catcaagatg ggttgctgaa
    13141 catattttaa acaggtgaaa aagggtgagc gatttttgat agttgaacca ggcactttaa
    13201 gtttaactag ggcgtcatta tttattaaat t
//
LOCUS       DAPOAV010000102        13204 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.102, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000102 DAPOAV010000000
VERSION     DAPOAV010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13204
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.102"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(32..226)
                     /locus_tag="RN951_003707"
                     /pseudo
     CDS             complement(32..226)
                     /locus_tag="RN951_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313209.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            234..563
                     /locus_tag="RN951_003708"
     CDS             234..563
                     /locus_tag="RN951_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001324015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX2528649.1"
                     /translation="MKRLQAFKFRLRPGGQQEREMRRFAGACRFVFNRALALQNENHE
                     AGNKYIPYGKMASWLVEWKNATETQWLKDSPSQPLQQSLKDPERAYKNFFRLRHHAQT
                     VCYLSRL"
     gene            complement(445..942)
                     /locus_tag="RN951_003709"
     CDS             complement(445..942)
                     /locus_tag="RN951_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000334561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HDX2528650.1"
                     /translation="MCGRFAQSQTREDYLALLAEDIERDIPYDPEPIGRYNVAPGTKV
                     LLLSERDEHLHLDPVFWGYAPGWWDKPPLINARVETAATSHMFKPLWQHGRAICFADG
                     WFEWKKEGDKKQPYFIYRADGQAVFIVAIGSTPFERGDEAGRSFCKPAQGLSVTVAMA
                     VRANL"
     gene            complement(1051..1284)
                     /gene="yedF"
                     /locus_tag="RN951_003710"
     CDS             complement(1051..1284)
                     /gene="yedF"
                     /locus_tag="RN951_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HDX2528651.1"
                     /translation="MKNIVPDYRLDMVGEPCPYPAVATLEAMPQLKKGEILEVVSDCP
                     QSINNIPLDARNHGYTVLDIQQDGPTIRYLIQK"
     gene            complement(1281..2486)
                     /gene="yedE"
                     /locus_tag="RN951_003711"
     CDS             complement(1281..2486)
                     /gene="yedE"
                     /locus_tag="RN951_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium metabolism membrane protein YedE/FdhT"
                     /protein_id="HDX2528652.1"
                     /translation="MSWQQFKHAWLIKFWAPIPAVIAAGILSTYYFGITGTFWAVTGE
                     FTRWGGQLLQLFGVHAEEWGYFKIIHLEGSPLTRIDGMMILGMFGGCFAAALWANNVK
                     LRMPRSRIRIMQAIIGGIIAGFGARLAMGCNLAAFFTGIPQFSLHAWFFAIATAIGSW
                     FGARFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRFRLGMLVFFGLLGWALLTAMNQ
                     PKLGLAMLFGVGFGLLIERAQICFTSAFRDMWITGRTHMAKAIIIGMAVSAIGIFSYV
                     QLGVEPKIMWAGPNAVIGGLLFGFGIVLAGGCETGWMYRAVEGQVHYWWVGLGNVIGS
                     TILAYYWDDFAPALATDWDKINLLKTFGPMGGLLVTYLLLFAALMLIIGWEKRFFRRA
                     APQTAKEIA"
     gene            2673..3086
                     /locus_tag="RN951_003712"
     CDS             2673..3086
                     /locus_tag="RN951_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310694.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDX2528653.1"
                     /translation="MKKLAIAGALMLLAGCAEVENYNNVVKTPAPDWLAGYWQTKGPQ
                     RALVSPEAIGSLIVTKEGDTLDCRQWQRVIAVPGKLTLMSDDLTNVTVKRELYEVERD
                     GNTIEYDGMTMERVDRPTAECAAALDKAPLPTPLP"
     gene            complement(3120..4607)
                     /gene="amyA"
                     /locus_tag="RN951_003713"
     CDS             complement(3120..4607)
                     /gene="amyA"
                     /locus_tag="RN951_003713"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HDX2528654.1"
                     /translation="MRNPTLLQCFHWYYPEGGKLWPELAERADGFNDIGINMVWLPPA
                     YKGASGGYSVGYDSYDLFDLGEFDQKGSIPTKYGDKAQLLAAIDALKRNDIAVLLDVV
                     VNHKMGADEKEAIRVQRVNADDRTQIDEEIIECEGWTRYTFPARAGQYSQFIWDFKCF
                     SGIDHIENPDEDGIFKIVNDYTGEGWNDQVDDELGNFDYLMGENIDFRNHAVTEEIKY
                     WARWVMEQTQCDGFRLDAVKHIPAWFYKEWIEHVQEVAPKPLFIVAEYWSHEVDKLQT
                     YIDQVEGKTMLFDAPLQMKFHEASRMGRDYDMTQIFTGTLVEADPFHAVTLVANHDTQ
                     PLQALEAPVEPWFKPLAYALILLRENGVPSVFYPDLYGAHYEDVGGDGQTYPIDMPII
                     EQLDELILARQRFAHGVQTLFFDHPNCIAFSRSGTDEYPGCVVVMSNGDDGEKTIHLG
                     ENYGNKTWRDFLGNRQESVVTDENGEATFFCNGGSVSVWVIEEVI"
     gene            complement(4685..5050)
                     /gene="fliT"
                     /locus_tag="RN951_003714"
     CDS             complement(4685..5050)
                     /gene="fliT"
                     /locus_tag="RN951_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliT"
                     /protein_id="HDX2528655.1"
                     /translation="MNNAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAV
                     QEIAHLTEEVAPSTTMQEQLRPMLRLILDNESKVKQLLQIRMDELAKLVGQSSVQKSV
                     LSAYGDQSGFVLAPQDNLF"
     gene            complement(5050..5460)
                     /gene="fliS"
                     /locus_tag="RN951_003715"
     CDS             complement(5050..5460)
                     /gene="fliS"
                     /locus_tag="RN951_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HDX2528656.1"
                     /translation="MYAAKGTQAYAQIGVESAVMSASQQQLVTMLFDGVLSALVRARL
                     FMQDNNQQGKGVSLSKAINIIENGLRVSLDEESKDELTQNLIALYSYMVRRLLQANLR
                     NDVSAVEEVEALMRNIADAWKESLLSPSLIQDPV"
     gene            complement(5476..6891)
                     /gene="fliD"
                     /locus_tag="RN951_003716"
     CDS             complement(5476..6891)
                     /gene="fliD"
                     /locus_tag="RN951_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HDX2528657.1"
                     /translation="MASISTLGVGSGLDLSSILDSLEAAEKSTLTPISKQQSSYTAKL
                     SAYGTLKSALESFQTANTALNKADLFTATSTTSSSSAFSATTTGSAIAGKYTISVSQL
                     AQAQTLTTKNSQKDSKAAIATSDSVLTIQQGGGKDPVTIDISAGNSSLSGIRDAINNA
                     KAGVSASIINVGNGEYRLSITANDTGSNNAMKLSVSGDSALESFMGYNGTPGDSSNGM
                     IESVTAQNAKLTVNNVEIENSSNTISDSLEDITLNLNDVTTGNQTLTISKNTSKAENA
                     VKAWVDAYNTLQDTFSSLTKYTAVDAGAESQDSSNGALLGDSTLRTIQTQLKTLLANT
                     HSSSNYKTLAQIGITSDASTGKLEIATDKLQTALKNDAAGIGEMFIGDGKSTGVTTGI
                     SNNLTSWLSSTGIIQAAKDGVSKTLNNLTDQYNAASERIDTLMTRYKAQFTQLDVLMN
                     SLNSTSSYLTQQFDTSNSNSK"
     gene            7139..8188
                     /locus_tag="RN951_003717"
     CDS             7139..8188
                     /locus_tag="RN951_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079755.1"
                     /note="structural flagella protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin FliC"
                     /protein_id="HDX2528658.1"
                     /translation="MAQVINTNSLSLITQNNINKNQSALSTSIERLSSGLRINSAKDD
                     AAGQAIANRFTSNIKGLTQAARNANDGISLAQTAEGALSEINNNLQRIRELTVQASTG
                     TNSDSDLSSIQDEIKSRLDEIDRVSGQTQFNGVNVLSKNDSMKIQIGANDNQTISIGL
                     QQIDSTTLNLKGFTVSGMADFSAAKLTAADGTAIAAADVKDAGGKQVNLLSYTDTASN
                     STKYAVVDSATGKYMEATVAITGTAAAVTVGAAEVAGAATADPLKALDAAIAKVDKFR
                     SSLGAVQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLS
                     KANQVPQQVLSLLQG"
     gene            8352..9071
                     /gene="fliA"
                     /locus_tag="RN951_003718"
     CDS             8352..9071
                     /gene="fliA"
                     /locus_tag="RN951_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor FliA"
                     /protein_id="HDX2528659.1"
                     /translation="MNSLYTAEGVMDKHSLWQRYVPLVRHEALRLQVRLPASVELDDL
                     LQAGGIGLLNAVERYDALQGTAFTTYAVQRIRGAMLDELRSRDWVPRSVRRNAREVAQ
                     AIGQLEQELGRNATETEVAERLGIDIADYRQMLLDTNNSQLFSYDEWREEHGDSIELV
                     TDDHQRENPLQQLLDSNLRQRVMEAIETLPEREKLVLTLYYQEELNLKEIGAVLEVGE
                     SRVSQLHSQAIKRLRTKLGKL"
     gene            9117..9668
                     /gene="fliZ"
                     /locus_tag="RN951_003719"
     CDS             9117..9668
                     /gene="fliZ"
                     /locus_tag="RN951_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310687.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliZ"
                     /protein_id="HDX2528660.1"
                     /translation="MMVQHLKRRPLSRYLKDFKHSQTYCAHCRKLLDRITLVRDGKIV
                     NKIEISRLDALLDENGWQTEQKSWAALCRFCGDLHCKTQSDFFDIIGFKQFLFEQTEM
                     SPGRVREYVVRLRRLGNHLHEQNISLDQLQDGFLDEILAPWLPTTSTNNYRIALRKYQ
                     HYQRQTCTGLVQKSTSLPASDIY"
     gene            9756..10556
                     /gene="tcyJ"
                     /locus_tag="RN951_003720"
     CDS             9756..10556
                     /gene="tcyJ"
                     /locus_tag="RN951_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter substrate-binding
                     protein"
                     /protein_id="HDX2528661.1"
                     /translation="MKLAHLGRQALMGVMAVALVAGMSVKSFADEGLLNKVKERGTLL
                     VGLEGTYPPFSFQGDDGKLTGFEVEFAQQLAKHLGVEASLKPTKWDGMLASLDSKRID
                     VVINQVTISDERKKKYDFSTPYTISGIQALVKKGNEGTIKTAADLKGKKVGVGLGTNY
                     EEWLRQNVQGVDVRTYDDDPTKYQDLRVGRIDAILVDRLAALDLVKKTNDTLAVTGEA
                     FSRQESGVALRKGNEDLLKAVNDAIAEMQKDGTLQALSEKWFGADVTK"
     gene            10661..11647
                     /gene="dcyD"
                     /locus_tag="RN951_003721"
     CDS             10661..11647
                     /gene="dcyD"
                     /locus_tag="RN951_003721"
                     /EC_number="4.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416429.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-cysteine desulfhydrase"
                     /protein_id="HDX2528662.1"
                     /translation="MPLHNLTRFPRLEFIGAPTPLEYLPRFSDYLGREIFIKRDDVTP
                     MAMGGNKLRKLEFLAADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENP
                     IGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPNAQLEELATRVEAQGFRPYVIPVGG
                     SNALGALGYVESALEIAQQCEGAVNISSVVVASGSAGTHAGLAVGLEHLMPESELIGV
                     TVSRSVADQLPKVVNLQQAIAKELELTASAEILLWDDYFAPGYGVPNDEGMEAVKLLA
                     RLEGILLDPVYTGKAMAGLIDGISQKRFKDEGPILFIHTGGAPALFAYHPHV"
     gene            11662..12330
                     /gene="tcyL"
                     /locus_tag="RN951_003722"
     CDS             11662..12330
                     /gene="tcyL"
                     /locus_tag="RN951_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter permease"
                     /protein_id="HDX2528663.1"
                     /translation="MQESIQLVIDSLPFLLKGAGYTLQLSIGGMFFGLLLGFILALMR
                     LSPIWPVRWLARFYISIFRGTPLIAQLFMIYYGLPQFGIELDPIPSAMIGLSLNTAAY
                     AAETLRAAISSIDKGQWEAAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDT
                     SLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQE
                     REPK"
     gene            12327..13079
                     /gene="yecC"
                     /locus_tag="RN951_003723"
     CDS             12327..13079
                     /gene="yecC"
                     /locus_tag="RN951_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine ABC transporter ATP-binding protein
                     YecC"
                     /protein_id="HDX2528664.1"
                     /translation="MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTT
                     LLRSINLLEQPEAGTITVGDITIDTARSLSQQKSLIRQLRQHVGFVFQNFNLFPHRTV
                     LENIIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALA
                     MRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMD
                     QGRIVEQGAAKALFADPQQPRTRQFLEKFLLQ"
BASE COUNT         3256 a         3295 c         3420 g         3233 t
ORIGIN      
        1 tggttgtctg gagattcagg gggccagtct agccatccat ttcaacccgt tcagcttcaa
       61 aatcagcaca tacatttgaa aagtaagtgc gtagtttttc tgtcgcgtca tggtcaaaaa
      121 tctgacgtcg gtatttagta acgaagacta ggtgaacatg cttcaggaaa acacaatgcc
      181 ttccgcgtcg gatatcggtt tcttttttca taggccaaag tatgatttgg cccatgaaac
      241 gactacaggc attcaaattc cggttaagac caggtggtca acaggagcgt gaaatgaggc
      301 gcttcgcagg cgcatgtcgt ttcgttttca atcgtgctct ggcgcttcag aatgagaatc
      361 atgaggccgg taataaatac atcccttacg ggaaaatggc ttcctggttg gttgagtgga
      421 aaaatgccac tgaaacgcaa tggcttaaag attcgccctc acagccattg caacagtcac
      481 tgaaagaccc tgagcgggct tacaaaaact tcttccggct tcgtcaccac gctcaaacgg
      541 tgtgctacct atcgcgacta taaaaacagc ttgtccatca gcacgataga taaaataagg
      601 ctgctttttg tcgccttctt ttttccactc aaaccagcca tcggcaaaac agattgcccg
      661 accatgttgc cagagcggtt taaacatgtg actggttgcg gcagtttcta cgcgggcgtt
      721 aatcagcggc ggtttatccc accatccggg agcatatccc cagaaaaccg gatccagatg
      781 aaggtgttca tcacgttcac tgagcagaag gactttggtt cccggcgcga cgttgtatct
      841 gccaataggt tcgggatcgt agggaatatc gcgttcaata tcttccgcga gaagcgcaag
      901 gtaatcttca cgcgtttggg attgggcaaa gcgtccacac atagaaacct cctgaggtca
      961 cactgaaaag aataggagag ggggcgggtt aaatctatgt gatagagagg caacgatatt
     1021 cccgctgtgg gccacagcgg gaatgaggga ttacttctga attaaataac gaatggtcgg
     1081 cccgtcttgc tgaatatcca gcaccgtata gccgtgatta cgcgcatcca gtggaatatt
     1141 attgatcgac tgcggacagt cgctcaccac ttccaggatc tctccttttt ttaactgcgg
     1201 catcgcctca agggttgcga ctgccggata agggcagggt tcacccacca tatcaagacg
     1261 gtaatcagga acgatatttt tcatgcgatc tccttagcag tctgcggtgc cgcacggcgg
     1321 aagaagcgtt tttcccagcc aataatcaac attagagcag caaacaacag caaatatgtc
     1381 accagcaggc cgcccatcgg gccaaaggtt ttcagcaggt tgattttgtc ccagtcggtg
     1441 gccagcgccg gagcgaaatc atcccagtag tacgccagaa tcgttgagcc gatcacgttg
     1501 cccagaccga cccaccagta gtgcacctgg ccttctaccg cgcggtacat ccagccggtt
     1561 tcgcagccgc ctgccagcac gatgccaaaa ccaaacagta aaccaccaat taccgcgttt
     1621 ggtcccgccc acatgatttt gggttcaacg cctaactgta cgtaactgaa gatcccgatg
     1681 gcacttaccg ccataccgat aatgattgct ttcgccatat gggtacgtcc ggtgatccac
     1741 atgtcgcgga acgccgaagt aaagcagatt tgcgcacgtt caatcagtaa accaaagccg
     1801 acgccaaaca gcattgccag ccccagtttg ggctggttca tcgccgtcag cagcgcccag
     1861 cccagcaggc cgaaaaagac cagcatcccg agacgaaaac gacgccgcgc ctgatccggt
     1921 ttttgcgtca acggtgaggc agcagaaact ttctgcattt tcacgggaat acggaagatg
     1981 ggcagaaggg taaagcgcgc gccaaaccat gaaccaatgg cagtggcgat ggcaaagaac
     2041 caggcgtgca gcgagaactg tggaattccg gtaaagaacg ccgccaggtt acagcccatt
     2101 gccagacgtg cgccaaaacc ggcgataata ccgccaatga tggcctgcat aatgcggata
     2161 cggctgcgcg gcatgcgcag tttgacattg ttggcccaca gcgctgcggc aaaacagccg
     2221 ccaaacatac cgaggatcat cattccgtcg atgcgggtta atggcgatcc ttccagatgg
     2281 ataattttaa aataacccca ctcttcagca tggacgccga acaactgcag gagctgaccg
     2341 ccccaacggg taaattcacc tgtgacagcc caaaaggtgc cagtgatgcc aaaatagtaa
     2401 gtggagagaa tacccgccgc gatgaccgcg gggatgggcg cccagaattt aatcaaccag
     2461 gcgtgtttga attgctgcca tgacatgaat gtagcctctg aactcagaag gtttgaaaca
     2521 agagtcgcga atcatacacc atgcaaattt attttcgggg taataattca caaaaataat
     2581 ggttagatca aatttctctc tgaacctgga aaggctggcg acatcagggc tttaatgcca
     2641 caatcctctt ttcttctcat gcaggacgaa tgatgaaaaa actcgcaatt gcaggtgcgc
     2701 tcatgttgct ggcgggctgt gccgaagtcg aaaactataa caatgtcgtg aaaacccccg
     2761 cgccggactg gctggcgggc tactggcaga ccaaagggcc gcaacgtgcg ttggtcagtc
     2821 cggaagcgat aggcagcctc attgtcacta aagagggcga taccttggat tgccgtcagt
     2881 ggcagcgggt gattgccgtg ccgggtaagt tgacattgat gtctgatgat ctcactaacg
     2941 ttaccgtaaa acgtgagctg tacgaggttg agcgtgacgg taacaccatt gagtacgatg
     3001 gtatgacgat ggagcgtgtg gatcgcccga cggcagagtg tgccgccgcg ctggataaag
     3061 cgccgttacc gacgccactg ccgtaatgaa atctccccgg cttgccgccg gggatggatt
     3121 taaatcacct cttcgataac ccacacgctg acgctgccgc cgttgcaaaa gaaggtcgct
     3181 tcgccgtttt cgtctgtcac tacgctctct tgccggttcc ccagaaaatc acgccaggtt
     3241 ttattgccgt aattctctcc cagatgaatg gttttttcgc catcatctcc gttcgacatg
     3301 accaccacgc agccgggata ttcgtcggtg ccactgcggc taaaggcaat gcagttcgga
     3361 tggtcgaaaa ataacgtctg tacaccgtgg gcgaaacgct gacgggcgag aattaactca
     3421 tcaagctgtt cgattattgg catatctatc ggataggttt gcccgtcacc accgacatct
     3481 tcgtaatgtg caccgtagag gtccggatag aataccgaag gaacgccatt ttcccgcaac
     3541 aaaattaagg catacgccag cggtttaaac cacggttcga cgggggcttc gagggcttgc
     3601 aacggttggg tgtcgtggtt ggcaacgagg gttacggcgt gaaaaggatc ggcttccacc
     3661 agcgtcccag tgaagatctg cgtcatgtcg tagtcgcgac ccatgcgcga tgcttcatgg
     3721 aatttcatct gcagcggcgc atcaaacagc atggttttgc cttccacctg atcaatatac
     3781 gtttgcagtt tatcgacttc atgcgaccag tattcagcca caataaacaa cggctttggc
     3841 gcaacttcct gtacgtgttc gatccactct ttataaaacc atgccggaat atgtttgacc
     3901 gcatcaagac gaaagccgtc gcattgcgtt tgttccatca cccagcgcgc ccagtattta
     3961 atctcttccg tcacggcatg attgcgaaaa tcgatattct cccccatcag ataatcgaaa
     4021 ttaccgagtt catcatcaac ctgatcgttc cagccttctc cggtatagtc gttaacaatt
     4081 ttaaaaatgc catcttcatc agggttttcg atatggtcga taccgctaaa acatttgaaa
     4141 tcccagataa actgcgagta ttgcccggca cgagcgggga aggtgtaacg cgtccagcct
     4201 tcacactcaa tgatttcttc gtcaatttgc gtacggtcat cagcatttac acgctgcacg
     4261 cgaatagctt ctttttcatc cgcgcccatt ttgtggttga ctaccacgtc cagcagcacc
     4321 gcaatgtcat tacgtttcag ggcgtcaatg gcggccagca gttgtgcttt atcaccatat
     4381 ttagtaggga tgctgccttt ctgatcaaac tcacctagat caaataaatc ataggagtcg
     4441 tagccgaccg aatagccgcc cgatgcgcct ttataggcgg gcggcaacca gaccatattg
     4501 ataccaatat cattaaaacc gtctgcgcgc tcggccagtt caggccagag cttaccgcct
     4561 tccgggtaat accagtgaaa acattgtaac agcgtgggat tacgcattct tcgactccat
     4621 tcaaggggaa tattagaagc gtagccgtaa tcggattatt cgcgagccat cggctcatta
     4681 agattcaaaa gaggttatcc tgcggagcca gcacaaagcc gctctgatcg ccataggcac
     4741 ttaacaccga tttttgcacc gatgactgac cgaccagttt cgccagttca tccatccgaa
     4801 tctgtaataa ctgttttacc ttgctttcgt tgtcgagaat caggcgcagc atcgggcgga
     4861 gctgctcctg catcgtagtg gacggggcaa cctcttcagt caggtgtgcg atctcctgca
     4921 ccgcattcac atacgccatt tcgctggcga tgagttcgtc ccattgttct tccgttgcca
     4981 ggcgtaacat tagctggctt ttttcgacga gttgttgcca ggcgaaatac aaatgcggtg
     5041 cattgttcat cagactgggt cctgaatcaa agaaggggag agtaaagact ctttccaggc
     5101 atcggcaata ttgcgcatta atgcttccac ttcttcgact gcggagacat cgttacgtaa
     5161 attggcttgc agcaagcgcc tgaccatata gctataaaga gcaatcaagt tttgggttaa
     5221 ttcgtctttg ctctcttcat caagactcac ccgcagtccg ttctcaatga tgttgatcgc
     5281 ttttgataaa gagacgcctt tgccttgctg attgttgtct tgcataaaca ggcgcgctct
     5341 aaccagtgcg ctcagcactc catcaaatag catggtgacc agctgctgtt ggctggcgct
     5401 cattacggcg ctttcgacgc caatttgtgc ataggcctgg gtgccttttg ccgcgtacat
     5461 agtctctcct gaagattatt tcgagttgct atttgaggtg tcgaactgct gtgtcagata
     5521 gctactagtg gagttcagcg agttcattaa cacatctaat tgggtgaact gggctttata
     5581 gcgcgtcatt aaggtatcga tacgttcact ggctgcgttg tactggtcgg tcaaattatt
     5641 cagcgttttg ctgacgccat cttttgctgc ctggattatc ccggtggaag agagccaact
     5701 ggtcaggttg ttactaatgc cggtggttac cccagtactt ttgccgtcac ctataaacat
     5761 ttcaccgata ccagcggcat cattttttag cgccgtttgc agtttgtcgg tcgcgatttc
     5821 cagcttgccg gtactggcat cgctggtaat gccaatctgt gccagcgttt tatagtttga
     5881 actgctgtga gtattggcga gcaaggtttt aagctgagtc tggatggtgc gcagtgtgga
     5941 gtcaccgagt aatgcgccat tactggagtc ctgactttca gctccggcat cgacagcggt
     6001 gtatttggtt aagctgctga atgtatcctg caatgtgtta taggcatcca cccacgcttt
     6061 aaccgcattt tcagctttgg atgtgttttt actgatggtc agtgtctgat taccggtggt
     6121 gacgtcattc aggttgaggg tgatatcttc cagtgagtcg ctgatagtgt tactgctgtt
     6181 ttcaatctca acgttattga ctgtcagttt ggcgttttgc gcggtgacgc tttcaatcat
     6241 gccattgctg ctatcacccg gcgttccgtt gtaacccata aaactttcca gggcgctgtc
     6301 gccgctgacg ctaagtttca tagcgttatt gctgcccgta tcgttagcgg tgatggacag
     6361 acgatattcg ccgtttccca cattgatgat actggcgctg acaccagctt tggcgttgtt
     6421 aatggcatcg cgaatgccgg aaagtgacga gttacccgcg ctgatatcaa tcgtgaccgg
     6481 atctttaccg ccgccttgtt ggatggtcag tacgctatcg ctggtggcga tggcggcttt
     6541 actgtctttt tgactatttt ttgttgtcag cgtctgtgcc tgcgccagtt ggctaacgct
     6601 aatggtgtat ttcccagcaa tcgcgctgcc cgtggtggtg gcgctgaaag ccgatgaact
     6661 gctggtggtt gaggtggcgg taaataaatc ggctttattc agtgctgtgt tggctgtctg
     6721 gaaactctct agtgcacttt tcagcgtccc gtaggcgctc agtttcgcgg tgtaagagct
     6781 ttgctgtttt gatatcggcg tcagggtaga tttttctgcc gcctccagac tgtcaaggat
     6841 gctgcttaag tccagccccg acccaacccc aagcgttgaa atactagcca tatagtttcc
     6901 ttaatcatgc gacgtgtata gaacgaatac cggggttatc ggcgtaagcg gggtaaagtt
     6961 tacgatttat tttttgcctt aatggcacga acagcaacga ggaaggggag tatttcgacc
     7021 gctagaaaaa aattctaaag gttgtgagtg accagacgat aacagggttg acggcgacga
     7081 agccgaaggg tggaagccca atacttaaac cgtagacttg aaaacaggaa aatgaattat
     7141 ggcacaagtc attaatacca acagcctctc gctgatcact cagaacaaca tcaacaaaaa
     7201 ccagtctgcg ctgtcgactt ctatcgagcg cctctcttct ggtctgcgta ttaacagcgc
     7261 taaagatgac gccgcgggcc aggcgattgc taaccgcttt acttctaaca tcaaaggtct
     7321 gactcaggcc gcacgtaacg ccaacgacgg tatttctctg gcgcagacgg ctgaaggcgc
     7381 gctgtcagag attaacaaca acttgcagcg tattcgtgaa ctgaccgttc aggcctctac
     7441 cggcacgaac tctgattccg acctgtcttc tattcaggac gaaatcaaat cccgtcttga
     7501 tgaaattgac cgtgtatctg gtcagaccca gttcaacggt gtgaacgtgc tgtcgaaaaa
     7561 cgattcgatg aagattcaga ttggtgccaa tgataaccag acgatcagca ttggcttgca
     7621 acaaatcgac agtaccactt tgaatctgaa aggatttacc gtgtccggca tggcggattt
     7681 cagcgcggcg aaactgacgg ctgctgatgg tacagcaatt gctgctgcgg atgtcaagga
     7741 tgctgggggt aaacaagtca atttactgtc ttacactgac accgcgtcta acagtactaa
     7801 atatgcggtc gttgattctg caaccggtaa atacatggaa gccactgtag ccattaccgg
     7861 tacggcggcg gcggtaactg ttggtgcagc ggaagtggcg ggagccgcta cagccgatcc
     7921 gttaaaagca ctggatgccg caatcgctaa agtcgacaaa ttccgctcct ccctcggtgc
     7981 cgttcaaaac cgtctggatt ctgcggtcac caacctgaac aacaccacca ccaacctgtc
     8041 tgaagcgcag tcccgtattc aggacgccga ctatgcgacc gaagtgtcca acatgtcgaa
     8101 agcgcagatt atccagcagg cgggcaactc cgtgctgtct aaagccaacc aggtaccgca
     8161 gcaagttctg tctctgttac aaggctaatg gccttaacct gcctgacccc gctaccggcg
     8221 gggttttttc tgcccgcaat ttaccggtaa cccccaaata acccctcatt tcacccacta
     8281 atcgtccgat taaaaaccct gcagaaacgg ataatcatgc cgataactca tataacgcag
     8341 ggctgtttat cgtgaattca ctctataccg ctgaaggtgt aatggataaa cactcgctgt
     8401 ggcagcgtta tgtcccgctg gtgcgtcacg aagcattgcg cctgcaggtt cgactgcccg
     8461 cgagcgtgga acttgacgat ctgctacagg cgggcggcat tgggttactt aatgccgtcg
     8521 aacgctatga cgccctacaa ggaacggcat ttacaactta cgcagtgcag cgtatccgtg
     8581 gcgctatgct ggatgaactt cgcagccgtg actgggtgcc gcgcagcgtg cgacgcaacg
     8641 cgcgtgaagt ggcacaggca atagggcaac tggagcagga acttggccgc aacgccacgg
     8701 aaactgaggt tgcggaacgt ttagggatcg atattgccga ttatcgccaa atgttgctcg
     8761 acaccaataa cagccagctc ttctcctacg atgagtggcg cgaagagcac ggcgatagca
     8821 tcgaactggt tactgatgat catcagcgag aaaacccgct acaacaactg ctggacagta
     8881 atctgcgcca gcgggtgatg gaagctatcg aaacgttgcc ggagcgcgaa aaactggtat
     8941 taaccctcta ttaccaggaa gagctgaatc tcaaagagat tggcgcggtg ctggaggtcg
     9001 gggaatcgcg ggtcagtcag ttacacagcc aggccattaa acggttacgc actaaactgg
     9061 gtaagttata acgtcagtaa atgccgcact ttaattttga ctaccaggag ttcttaatga
     9121 tggtgcagca cctgaaaaga cggccattaa gccgctatct taaagacttt aaacacagcc
     9181 agacttattg cgcgcattgc cgtaaattac tcgatcgcat taccctcgtt cgcgacggca
     9241 aaatagtgaa taaaatcgag atttcccgcc tggacgcgct gcttgatgaa aatggctggc
     9301 aaacggaaca aaaatcatgg gcggcattgt gccgattttg cggtgattta cattgcaaaa
     9361 cgcagagtga ttttttcgat attatcggct ttaagcaatt tctttttgag caaactgaaa
     9421 tgagcccagg tagggtgcgt gaatatgtcg ttcgtctgcg ccgtttgggt aatcatcttc
     9481 acgagcaaaa tatttccctc gatcagctgc aggacggttt ccttgatgaa atcctcgccc
     9541 cgtggctgcc cactaccagc accaacaatt accgcatcgc gttacggaag tatcaacact
     9601 atcagcgtca aacgtgtacc ggacttgtgc agaaatccac cagtctgcct gcttctgata
     9661 tatattaaat aagaataaga tgtagcagag ttgtttttgt gtttacaaac aatggctcta
     9721 cactgcaaac agacataaca acattcgggg tgaatatgaa attagcacat ctgggacgtc
     9781 aggcattgat gggtgtgatg gccgtggcgc tggttgcggg catgagcgtt aaaagttttg
     9841 cagatgaagg tctgcttaat aaagttaaag agcgcggtac gctgctcgta gggctggaag
     9901 gaacttatcc gccgttcagt tttcaggggg atgacggcaa attaaccggt tttgaagtgg
     9961 aatttgccca acagctggca aaacatcttg gcgttgaggc gtcactaaaa ccgaccaaat
    10021 gggacggtat gctggcgtcg ctggactcta aacgcattga tgtggtgatt aatcaggtca
    10081 ccatttctga cgagcgcaag aaaaaatacg atttctctac cccttacacc atttccggta
    10141 ttcaggcgct ggtgaaaaaa ggtaacgaag gcaccattaa aacagctgct gatctgaaag
    10201 gcaaaaaagt gggtgtcggc ctgggcacca actatgaaga gtggctgcgt cagaatgttc
    10261 agggcgtcga tgtgcgtacc tatgatgatg acccgaccaa atatcaggat ctgcgcgtag
    10321 gccgtatcga tgcgatcctc gttgaccgtc tggcggcgct ggatctggtg aagaaaacca
    10381 acgatacgct ggcagtaacc ggtgaagcat tctcccgtca ggagtctggc gtggcgctgc
    10441 gtaaaggaaa tgaagacctg ctgaaagcag tgaatgatgc aattgcggaa atgcaaaaag
    10501 atggcactct gcaagccctt tccgaaaaat ggtttggtgc tgatgtgacc aaataatcag
    10561 cataatgaca aaaaagggcg ctttcactag cgcctttttt atttacgcgt tttcagcgtg
    10621 cataataaga aaatcacaac aacacacatc ggaggctgtt atgccactgc ataatttaac
    10681 ccgttttcca cggctggagt ttatcggcgc gccaacgccg ctcgaatatc tgccgcgctt
    10741 ttctgattat cttggacggg aaattttcat caaacgggat gacgtcacac ccatggcaat
    10801 gggcggcaat aaattacgta agctggaatt tctcgcggca gatgctctgc gtgaaggtgc
    10861 cgatacgctg attactgccg gggcgatcca gtctaaccat gtgcgccaga ctgccgcagt
    10921 tgcggcgaaa ctcggtctgc actgcgtggc gctgctggaa aatcctattg gcacaaccgc
    10981 agaaaactat ttaaccaacg gcaatcgttt gttgctggat ctgttcaata cccagattga
    11041 aatgtgcgac gcactgaccg atcccaatgc ccaactggaa gagctggcga cgcgagtcga
    11101 agcacaaggc tttcgcccgt atgtcattcc ggttggcggt tctaatgctc tgggcgcgct
    11161 gggttatgtg gagagtgcgc tggaaattgc gcaacagtgt gaaggggcgg ttaatatttc
    11221 gtcggtggtg gtcgcatcgg gcagtgccgg aactcacgcc ggactggctg ttgggctgga
    11281 acacctgatg cctgaaagcg aactgattgg cgtgaccgtg tcgcgttccg ttgccgatca
    11341 attgccgaaa gtggttaacc tacaacaggc gattgcgaaa gaactggagc tgaccgcatc
    11401 agcggaaatt ttactctggg atgactattt tgcacctggc tacggcgtgc cgaacgacga
    11461 aggcatggaa gcagtgaaat tgctggcgcg gctggaaggc attctgcttg atcctgtgta
    11521 taccggaaaa gcgatggcgg gtctgattga cggtatcagt cagaaacgtt tcaaagatga
    11581 agggccgatt ctgtttattc ataccggcgg tgcgcctgcg ctgttcgcct atcatcccca
    11641 cgtttagctc cggaaacgct catgcaagaa agtatacaac tggttattga ttccttgccg
    11701 ttcctgctga aaggtgctgg gtatacgctg caactcagta tcggcggcat gttttttggc
    11761 ttactgctcg ggtttattct cgcgctgatg cgcctgtcgc caatctggcc cgtgcgctgg
    11821 ctggcgcgtt tttatatctc tatttttcgt ggtacgccgc tcatcgcaca actgtttatg
    11881 atctattacg gcctgccgca gtttggtatc gaattagatc ccattccgtc agcaatgatt
    11941 ggtctgtcgt tgaacactgc cgcctatgct gccgaaacgc tgcgcgccgc catttcttct
    12001 attgataaag gtcagtggga agcggcagcc agtattggta tgacgccgtg gcagaccatg
    12061 cgtcgcgcga ttttgccaca ggcggcgcgt gtggcgttgc cgccgctgtc gaacagcttt
    12121 atcagcctgg taaaagatac gtcgctggcc gcgacaatcc aggtgccgga gctgttccgt
    12181 caggcgcagt tgattacctc gcgtacgctg gaggtgttca ccatgtatct ggcggcttcg
    12241 ctcatctact ggatcatggc gactgtgtta tcgacgttgc agaaccattt tgagaatcaa
    12301 cttaatcgcc aggagagaga accaaaatga gtgccattga agttaagaac ctggtgaaaa
    12361 aattccacgg tcagacggtg ctgcacggta tcgacctcga ggtaaagcct ggcgaagtgg
    12421 tggcaattat cggtccgagt ggttccggca aaaccacgtt gctacgcagc ataaatctgc
    12481 tggaacaacc cgaagcggga acgatcaccg ttggcgatat cactattgat actgcacgtt
    12541 cattaagtca gcaaaaatcg ctgattcgcc agttgcgtca gcacgtcggg tttgtcttcc
    12601 agaactttaa tttgtttccg catcgtacgg tgctggagaa cattattgaa gggccggtga
    12661 tcgtcaaagg cgaaccgaaa gaagaggcca cggcgcgcgc tcgcgagcta ctggcgaaag
    12721 ttgggctggc cggtaaagaa accagctatc cacgtcgttt gtctggcggt caacagcagc
    12781 gtgttgcgat tgcgcgtgcg ctggcaatgc gtcctgaggt gattttgttt gacgagccaa
    12841 cgtcagcgct ggatccagag ctggtgggcg aagtcctgaa caccatccgt cagctggcgc
    12901 aggaaaagcg cacgatggtg attgtgacgc acgaaatgag ctttgcccgg gatgttgcgg
    12961 accgggcgat ttttatggac caggggcgga tagtcgagca gggggcagca aaagcgttat
    13021 ttgccgatcc ccagcagcct cgcacccgcc agttcctcga gaagtttctg ctgcaataat
    13081 aagaaaaaat cagccccgac gattcacctg tcggggcggg acgctatttc aagcgtgata
    13141 aaactgctta acaaatcagc ataactcatt aataacataa gagaatgtga tggcttgcaa
    13201 aagt
//
LOCUS       DAPOAV010000103        12985 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.103, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000103 DAPOAV010000000
VERSION     DAPOAV010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12985
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.103"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            115..1515
                     /locus_tag="RN951_003724"
     CDS             115..1515
                     /locus_tag="RN951_003724"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HDX2528665.1"
                     /translation="MDQKLLTDFRSELLDSRFGAKAISTIAESKRFPLHEMRDDVAFQ
                     IINDELYLDGNARQNLATFCQTWDDENVHKLMDLSINKNWIDKEEYPQSAAIDLRCVN
                     MVADLWHAPAPKNGQAVGTNTIGSSEACMLGGMAMKWRWRKRMEAAGKPTDKPNLVCG
                     PVQICWHKFARYWDVELREIPMRPGQLFMDPKRMIEACDENTIGVVPTFGVTYTGNYE
                     FPQPLHDALDKFQADTGIDIDMHIDAASGGFLAPFVAPDIVWDFRLPRVKSISASGHK
                     FGLAPLGCGWVIWRDEEALPQELVFNVDYLGGQIGTFAINFSRPAGQVIAQYYEFLRL
                     GREGYTKVQNASYQVAAYLADEIAKLGPYEFICTGRPDEGIPAVCFKLKDGEDPGYTL
                     YDLSERLRLRGWQVPAFTLGGEATDIVVMRIMCRRGFEMDFAELLLEDYKASLKYLSD
                     HPKLQGIAQQNSFKHT"
     gene            1885..2709
                     /gene="gadX"
                     /locus_tag="RN951_003725"
     CDS             1885..2709
                     /gene="gadX"
                     /locus_tag="RN951_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadX"
                     /protein_id="HDX2528666.1"
                     /translation="MQSLHGNCLIAYARHKYILTMVNGEYRYFNGGDLVFADASQIRV
                     DKCVENFVLVSRDTLSLFLPMLKEEALNLHAHKKISSLLVHHCSRDIPVFQEVAQLSQ
                     NKNLRYAEMLRKRALIFALLSVFLEDEHFIPLLLNVLQPNMRTRVCTVINNNIAHEWT
                     LARIASELLMSPSLLKKKLREEETSYSQLLTECRMQRALQLIVIHGFSIKRVAVSCGY
                     HSVSYFIYVFRNYYGMTPTEYQERSAQGLPNRDSAASIVAQGNFYGTDRSAEGIRL"
     gene            3077..3805
                     /gene="gadW"
                     /locus_tag="RN951_003726"
     CDS             3077..3805
                     /gene="gadW"
                     /locus_tag="RN951_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadW"
                     /protein_id="HDX2528667.1"
                     /translation="MTHVCSVILIRRSFDIYHEQHKISLHNESIVLLEKNLADDFAFC
                     SPDTRRLDIDELTVCHYLQNIRQLPRNLGLHSKDRLLINQSPPMPLVTAIFDSFNESG
                     VNSPILSNMLYLSCLSMFSHKKELIPLLFNSISTVSGKVERLISFDIAKRWYLRDIAE
                     RMYTSESLIKKKLQDENTCFSKILLASRMSMARRLLELRQIPLHTIAEKCGYSSTSYF
                     INTFRQYYGVTPHQFAQHSPGTFS"
     gene            complement(4168..7281)
                     /locus_tag="RN951_003727"
     CDS             complement(4168..7281)
                     /locus_tag="RN951_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HDX2528668.1"
                     /translation="MANYFIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTIT
                     VSATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSSTSDAAGNASITLTFETGTSPDI
                     AQVQVQNKLQLAMPSLPEAVQQQGISVDKSSSNILMVAAFISDNGSLNQYDIADYVAS
                     NIKDPLSRTAGVGSVQLFGSEYAMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQ
                     LGGMPQAADQQLNASIIVQTRLQTPEEFGKILLKVQQDGSQVLLRDVARVELGAEDYS
                     TVARYNGKPAAGIAIKLATGANALDTSRAVKEELNRLSAYFPASLKTVYPYDTTPFIE
                     ISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVIAEDKLPPKEATHKSMGQIQRALVGIAVVLS
                     AVFMPMAFMSGATGEIYRQFSITLISSMLLSVFVAMSLTPALCATILKAAPEGGHKPN
                     ALFARFNTLFEKSTQHYTDSTRSLLRCTGRYMVVYLLICAGMAVLFLRTPTSFLPEED
                     QGVFMTTAQLPSGATMVNTTKVLQQVTDYYLTKEKDNVQSVFTVGGFGFSGQGQNNGL
                     AFISLKPWSERVGEENSVTAIIQRAMIALSSINKAVVFPFNLPAVAELGTASGFDMEL
                     LDNGNLGHEKLTQARNELLSLAAQSPDQVTGVRPNGLEDTPMFKVNVNAAKAEAMGVA
                     LSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGTMAP
                     LSAYSSTEWTYGSPRLERYNGIPSMEILGEAAAGKSTGDAMKFMADLVAKLPAGVGYS
                     WTGLSYQEALSSNQAPALYAISLVVVFLALAALYESWSIPFSVMLVVPLGVVGALLAT
                     DLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVKMMQKEGKTPIEAIIEAARMRLRP
                     ILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIYFVPVFFVVVEHL
                     FARFKKA"
     gene            complement(7306..8463)
                     /gene="mdtE"
                     /locus_tag="RN951_003728"
     CDS             complement(7306..8463)
                     /gene="mdtE"
                     /locus_tag="RN951_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter subunit MdtE"
                     /protein_id="HDX2528669.1"
                     /translation="MNRRRKLLIPLLFCGAMLTACDDKSAENAAAMTPEVGVVTLSPG
                     SVNVLSELPGRTVPYEVAEIRPQVGGIIIKRNFIEGDKVNQGDSLYQIDPAPLQAELN
                     SAKGSLAKALSTASNARITFNRQASLLKTNYVSRQDYDTARTQLNEAEANVTVAKAAV
                     EQATINLQYANVTSPITGVSGKSSVTVGALVTANQADSLVTVQRLDPIYVDLTQSVQD
                     FLRMKEEVASGQIKQVQGSTPVQLNLENGKRYSQTGTLKFSDPTVDETTGSVTLRAIF
                     PNPNGDLLPGMYVTALVDEGSRQNVLLVPQEGVTHNAQGKATALILDKDDVVQLREIE
                     ASKAIGDQWVVTSGLQAGDRVIVSGLQRIRPGIKARAISSSQENASTESKQ"
     gene            8523..8801
                     /locus_tag="RN951_003729"
     CDS             8523..8801
                     /locus_tag="RN951_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528670.1"
                     /translation="MRDLQTSGIVGLSASKVGYRYSDRHGEVNDKKNVAVLPTVPASI
                     RATKGSTGGYTYQGNKVVLASPLVITGGNEISICIPRHASHQFQLLMS"
     gene            complement(8802..9329)
                     /gene="gadE"
                     /locus_tag="RN951_003730"
     CDS             complement(8802..9329)
                     /gene="gadE"
                     /locus_tag="RN951_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadE"
                     /protein_id="HDX2528671.1"
                     /translation="MIFLMTKDSFLLQGFWQLKDNHEMIKINSLSEIKKVGNKPFKVI
                     IDTYHNHILDEEAIKFLEKLDAERIIVLAPYHISKLKAKAPIYFVSRKESIKNLLEIT
                     YGKHLPHKNSQLCFSHNQFKIMQLILKNKNESNITSTLNISQQTLKIQKFNIMYKLKL
                     RRMSDIVTLGITSYF"
     gene            complement(10128..10700)
                     /gene="hdeD"
                     /locus_tag="RN951_003731"
     CDS             complement(10128..10700)
                     /gene="hdeD"
                     /locus_tag="RN951_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-resistance protein HdeD"
                     /protein_id="HDX2528672.1"
                     /translation="MLYIDKATILKFDLEMLKKHRRAIQFIAVLLFIVGLLCISFPFV
                     SGDILSTVVGALLICSGIALIVGLFSNRSHNFWPVLSGFLVAVAYLLIGYFFIRAPEL
                     GIFAIAAFIAGLFCVAGVIRLMSWYRQRSMKGSWLQLVIGVLDIVIAWIFLGATPMVS
                     VTLVSTLVGIELIFSAASLFSFASLFVKQQ"
     gene            10955..11287
                     /gene="hdeA"
                     /locus_tag="RN951_003732"
     CDS             10955..11287
                     /gene="hdeA"
                     /locus_tag="RN951_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-activated periplasmic chaperone HdeA"
                     /protein_id="HDX2528673.1"
                     /translation="MKKVLGVILGGLLLLPVVSNAADAQKAADNKKPVNSWTCEDFLA
                     VDESFQPTAVGFAEALNNKDKPEDAVLDVQGIATVTPAIVQACTQDKQANFKDKVKGE
                     WDKIKKDM"
     gene            11403..11729
                     /gene="hdeB"
                     /locus_tag="RN951_003733"
     CDS             11403..11729
                     /gene="hdeB"
                     /locus_tag="RN951_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417966.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-activated periplasmic chaperone HdeB"
                     /protein_id="HDX2528674.1"
                     /translation="MNISSLRKAFIFMGAVAALSLVNAQSALAANESAKDMTCQEFID
                     LNPKAMTPVAWWMLHEETVYKGGDTVTLNETDLTQIPKVIEYCKKNPQKNLYTFKNQA
                     SNDLPN"
     gene            11793..12440
                     /locus_tag="RN951_003734"
     CDS             11793..12440
                     /locus_tag="RN951_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDX2528675.1"
                     /translation="MTAEFIIRLILAAIACGAIGMERQMRGKGAGLRTHVLIGMGSAL
                     FMIVSKYGFADVLSLDHVGLDPSRIAAQVVTGVGFIGAGNILVRNQNIVGLTTAADIW
                     VTAAIGMVIGSGMYELGIYGSVMTLLVLEVFHQLTFRLMNKNYHLQLTLVNGNTVSML
                     DWFKQQKIKTDLVSLQENEDHEVVAIDIQLHATTSIEDLLRLLKGMAGVKGVSIS"
     gene            complement(12482..>12985)
                     /locus_tag="RN951_003735"
     CDS             complement(12482..>12985)
                     /locus_tag="RN951_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX2528676.1"
                     /translation="MFFTAMKNILSKGNVVHIQNEEEIDVMLHQNAFVIIDTLMNNVF
                     HSNFLTQIERLKPVHVIIFSPFNIKRCLGKVPVTFVPRTITIIDFVALINGSYCSVPE
                     ANVSLSRKQHQVLSCIANQMTTEDILEKLKISLKTFYCHKHNIMMILNLKRINELVRH
                     QHIDYLV"
BASE COUNT         3518 a         2952 c         3016 g         3499 t
ORIGIN      
        1 aagtcgtttt tctgcttagg attttgttat ttaaattaag cctgtaatgc cttgcttcca
       61 ttgcggataa atcctacttt tttattgcct tcaaataaat ttaaggagtt cgaaatggac
      121 cagaagctgt taacggattt ccgctcagaa ctactcgatt cacgttttgg cgcaaaggcc
      181 atttctacta tcgcggagtc aaaacgattt ccgctgcacg aaatgcgcga tgatgtcgca
      241 ttccagatta tcaatgatga attatatctt gatggcaacg ctcgtcagaa cctggccact
      301 ttctgccaga cctgggacga cgaaaacgtc cataaattga tggatttgtc gatcaataaa
      361 aactggatcg acaaagaaga atatccgcaa tccgcagcca tcgacctgcg ttgcgtaaat
      421 atggttgccg atctgtggca tgcgcctgcg ccgaaaaatg gtcaggccgt tggcaccaac
      481 accattggtt cttccgaggc ctgtatgctc ggcgggatgg cgatgaaatg gcgttggcgc
      541 aagcgtatgg aagctgcagg caaaccaacg gataaaccaa acctggtgtg cggtccggta
      601 caaatctgct ggcataaatt cgcccgctac tgggatgtgg agctgcgtga gatccctatg
      661 cgccccggtc agttgtttat ggacccgaaa cgcatgattg aagcctgtga cgaaaacacc
      721 atcggcgtgg tgccgacttt cggcgtgacc tacaccggta actatgagtt cccacaaccg
      781 ctgcacgatg cgctggataa attccaggcc gacaccggta tcgacatcga catgcacatc
      841 gacgctgcca gcggtggctt cctggcaccg ttcgtcgccc cggatatcgt ctgggacttc
      901 cgcctgccgc gtgtgaaatc gatcagtgct tcaggccata aattcggtct ggctccgctg
      961 ggctgcggct gggttatctg gcgtgacgaa gaagcgctgc cgcaggaact ggtgttcaac
     1021 gttgactacc tgggtggtca aattggtact tttgccatca acttctcccg cccggcgggt
     1081 caggtaattg cacagtacta tgaattcctg cgcctcggtc gtgaaggcta taccaaagta
     1141 cagaacgcct cttaccaggt tgccgcttat ctggcggatg aaatcgccaa actggggccg
     1201 tatgagttca tctgtacggg tcgcccggac gaaggcatcc cggcggtttg cttcaaactg
     1261 aaagatggtg aagatccggg atacaccctg tacgacctct ctgaacgtct gcgtctgcgc
     1321 ggctggcagg ttccggcctt cactctcggc ggtgaagcca ccgacatcgt ggtgatgcgc
     1381 attatgtgtc gtcgcggctt cgaaatggac tttgctgaac tgttgctgga agactacaaa
     1441 gcctccctga aatatctcag cgatcacccg aaactgcagg gtattgccca gcagaacagc
     1501 tttaaacaca cctgataaca taacgttgta aaaaccgaat gcccagcctt taaaaaaaca
     1561 gctgggcatt cggttgctta ttaatcgcaa taatatattg gctgtctatt catcgtgttg
     1621 ataagatata tgttatatga atgtttatta aatgtagcga ttgcctttaa tgtcacgaaa
     1681 agggattatt tgcttgctat taatttcact gcgttcttaa acacgttttt gtattataaa
     1741 tccagtcatc ctgcccgtag aacatcacac attatcatcc tgttctcccg cttcgtttaa
     1801 atttatttat caatcaattt gacttaagag ggcggcgtgc tacattaatt aacagtaata
     1861 tgtttatgta atattaagtc aactatgcaa tcattacatg ggaattgtct aattgcgtac
     1921 gcaagacata aatatattct caccatggtt aatggtgaat atcgctattt taatggcggt
     1981 gacctggttt ttgcggatgc aagccaaatt cgagtagata agtgtgttga aaattttgta
     2041 ttagtatcaa gggatacgct ttcattattt ctgccgatgc tcaaggagga ggcattaaat
     2101 cttcatgcac ataaaaaaat ttcttcatta ctcgttcatc actgtagcag agatattcct
     2161 gtttttcagg aagttgcgca actatcgcag aataagaatc ttcgctatgc agaaatgcta
     2221 cgtaaaagag cattaatctt tgcgttgtta tctgtttttc ttgaggatga gcactttata
     2281 ccgctgcttt tgaacgtttt gcaaccgaac atgcgaacac gagtttgtac ggttatcaat
     2341 aataatatcg cccatgagtg gacactagcc cgaatcgcca gcgagctgtt gatgagtcca
     2401 agcctgttaa agaaaaaatt gcgcgaagaa gagacatcat attcacagtt gcttactgag
     2461 tgtagaatgc aacgtgcttt gcaacttatt gttatacatg gcttttcaat taagcgagtc
     2521 gcagtgtcct gtggatatca cagcgtgtcg tatttcattt acgtctttcg aaattattat
     2581 gggatgacgc ccacagagta tcaggagcga tcggcgcagg gattgccgaa ccgtgactcg
     2641 gcggcaagta ttgttgcgca aggaaatttt tacggcactg accgttctgc ggaaggaata
     2701 agattataga attttactca gacataaaaa aaacccggca taggggaccg ggaagaggat
     2761 agtctgccgt ctccagacta ataaaccgtt ataacactcc ctgttggcac gggaaacttt
     2821 gtgctctcag taagttaaat ataactttta ctggaaataa gatcagccat ttttttataa
     2881 acataagcta tacgctgtgc gaaaatatat tcgtgctgca tttacttatt atcaattaac
     2941 tgttatgcaa aactactttg tggataaatt ttggtcctac caaatctggc agtttttgcg
     3001 ctaagaaaca gtctggcaac atttcattag tatactgaaa ttgaaataat cgcagtatga
     3061 aatataaggg ataatcatga ctcatgtctg ctcggtgatc ctcattcgtc gttcattcga
     3121 tatttatcat gaacagcata aaatatcgct gcataacgag agtatcgtgc tgctggagaa
     3181 aaatttggca gacgattttg cgttttgttc accggatacg cgacgactgg atatcgatga
     3241 gctgacagtt tgccattact tacaaaatat tcgtcagcta ccacgcaatt tagggttaca
     3301 tagcaaagac cgtctattaa ttaaccagtc accccccatg ccgctggtga cggcgatttt
     3361 tgatagcttc aatgaatccg gggtaaattc accgatactg agcaatatgc tctacctttc
     3421 ctgtttatcg atgttttctc ataagaaaga actgatcccc ttacttttca atagcatcag
     3481 cactgtttca ggaaaagttg aacgccttat tagctttgat atcgccaaac gttggtatct
     3541 gcgcgatatc gcggaaagaa tgtataccag cgagagtctc atcaaaaaaa agttgcagga
     3601 tgaaaatacc tgtttcagta aaatattact cgcttccagg atgtcgatgg ccagacgatt
     3661 actcgagtta cgtcaaattc ctctgcatac tattgcagaa aaatgtggct atagcagtac
     3721 gtcgtacttt ataaacacat ttcgacaata ttatggtgta acgccacatc agtttgcgca
     3781 acattcgcca ggtacctttt cctgacatat tttgcatttg aatattggtc aggatctcac
     3841 acctgcttca tgtgaaactc ttccctgatg atttctgccg ggctaccggc tagttctctt
     3901 tcgcagtttg ccaggcggta taggtatttt caggaggaaa agactcggca tgtttgggat
     3961 tattaagctg acaattcata cgattacggg aatgtgggtc agtattgtgc tgttcaaatt
     4021 gatgacgaat ggctggagtg gtttctactt tcagtgctgt gtactaagcc tggtattcct
     4081 gacggttagc tggttgttga gtggtgaatg gttagcagga aagagtaagg ctgaaccttc
     4141 acgttcaacc ttactctcat ttacacgtta cgctttttta aagcgggcaa agagatgttc
     4201 cactacaacg aaaaagaccg gaacgaagta aattgccagc actgttgcgg caaacatccc
     4261 gcccatcacg ccggtaccta ccgcgttttg cgcgccagaa ccggcaccat gactgataac
     4321 cagcggcagc acgccgagaa taaaggccag agaggtcatc aggattgggc gtaaacgcat
     4381 ccgcgccgct tcgatgattg cctctatcgg cgttttccct tctttctgca tcatcttaac
     4441 ggcaaattcg acaatcagga tggcgttctt ggcggaaagc ccgatggtgg tcagcaaacc
     4501 aacctggaag tagacgtcat tacttaagcc gcgcagatcg gtggccagta atgcgccaac
     4561 gacgcctaac ggaacaacca acatcaccga gaacggaatt gaccagctct catagagtgc
     4621 ggcgagggcg aggaacacca cgaccagtga aatggcatac agtgcaggag cctggtttga
     4681 ggataacgct tcctgatacg acagtccggt ccatgagtag ccgacgcctg ccggaagttt
     4741 agcgaccagg tctgccataa atttcatagc gtcaccggta cttttcccgg ccgccgcttc
     4801 acctaaaatc tccattgacg ggatgccgtt gtagcgttcc aatcgcggtg aaccataggt
     4861 ccattcggta gacgagtagg cagaaagcgg tgccatcgtg ccagaggcgt tgcgtacata
     4921 ccattggttg atgttatccg gcaacatacg gaacggcgtg cctgcctgga catacacttt
     4981 tttcacccgc ccctggttga ggaagtcgtt cacgtagctg ctgccgaagg cggtggaaat
     5041 tgtctggttg atatcagaca gcgccacacc cattgcctca gctttcgcgg cgttgacgtt
     5101 cactttgaac atcggcgtat cttccaggcc gttcgggcgt accccggtga cctggtcagg
     5161 cgattgcgct gccagtgata acagctcgtt tcgtgcctgg gttagttttt cgtgccccag
     5221 gttaccgttg tccagcagtt ccatatcaaa acctgacgcg gtacccagtt cagccaccgc
     5281 gggtaagttg aacgggaaga cgacggcttt attgatactg cttaacgcaa tcattgcccg
     5341 ctgaatgatc gcggtaaccg agttttcctc accgacacgt tcagaccacg gcttgagact
     5401 gataaacgcc aggccgttgt tttgcccctg gccgctgaag ccaaagccgc caacggtaaa
     5461 caccgactga acattatctt tctcttttgt aagataataa tccgtcacct gttgcagcac
     5521 tttcgtggtg ttaaccatgg tggcaccgga aggtaactgc gcggtggtca taaatacccc
     5581 ctgatcctct tctggtaaga aagaggtcgg tgtacgcagg aacagcaccg ccatcccggc
     5641 gcaaatcagc aggtagacca ccatgtagcg accggtacaa cgcaacagcg agcgggtgct
     5701 atcggtatag tgctgagttg atttttcaaa cagcgtgttg aagcgtgcga acagggcgtt
     5761 aggtttgtga ccgccttccg gcgcggcttt cagaatggtg gcgcacaggg caggggtcag
     5821 gctcattgcc acaaatactg aaagcagcat ggaggagatc agcgtgatgg agaactggcg
     5881 gtagatctcc ccggttgcgc cgctcataaa ggccatcggc ataaacactg cggaaagaac
     5941 aacagcaata ccgaccagcg cacgttggat ctgccccatc gatttatgcg tcgcttcctt
     6001 cggtggtagc ttatcttccg caatgacacg ctcgacgttc tccaccacca cgatggcgtc
     6061 atccaccagt aaccctatcg ccagcaccat cccgaacata gttaacgtgt tgatggtgaa
     6121 accgaccgcc gacaagatcg caaacgtccc gagaataacc accggtacgg caatcgtcgg
     6181 gatgattgtg gcacggaaat tctgcaaaaa cagatacatg accaggaaga cgaggatgat
     6241 agcctcaacc agtgttttaa aaacttcctg aatagaaatt tcgataaacg gcgtggtgtc
     6301 gtaaggataa accgtcttca gacttgcggg gaaataggct gataagcggt tcagctcctc
     6361 tttgactgcc cgcgaggtat ccagggcgtt tgctccggta gccagtttga tggcgatccc
     6421 ggcagcaggt ttgccgttat agcgcgccac ggtggaataa tcttccgctc caagttcgac
     6481 gcgggcgaca tcacgcagca gcacttgcga accatcttgc tgaactttca acaggatttt
     6541 gccaaattct tccggcgttt gcagacgcgt ctgcacaatg atcgaggcgt ttagttgctg
     6601 gtctgccgcc tgtggcatgc cacccagttg accaccggaa atctggttgt tttgcacctt
     6661 aatctgggaa ataacatcgg aaggtaccag attgtattta ttgagttttt gcgggtccag
     6721 ccagatacgc atggcgtact cggaaccaaa gagctgtacg ctaccaacgc ccgcggtacg
     6781 gcttagcggg tctttgatat tagacgctac atagtccgcg atatcgtact ggttgaggct
     6841 gccgttatca gaaataaacg ccgctaccat cagaatatta ctgctcgact tatcaacgct
     6901 aatcccctgc tgctgcaccg cttcaggtaa tgaaggcata gcgagttgca gtttattttg
     6961 cacctgaacc tgtgcgatat caggagatgt cccagtctcg aaggtcagag tgatagaggc
     7021 attacccgcc gcatcactgg ttgaagacat gtacatcagg ccatcaagcc cattcatatt
     7081 ttgctcaatc acctgagtga ccgagtcttc taccgtttgc gcatcggcac ctggataggt
     7141 agcgctgacg gtaatggtcg gtggcgcaat ctgcggatac tgcgcaaccg gtaagttcat
     7201 gatcgccaga ccacctgcaa gcatcataat aatggcaagt acccaggcaa aaaccgggcg
     7261 atcaataaaa tagttagcca tgaaagtccc cttaagcctg caacgttatt gtttcgattc
     7321 ggtgctggcg ttttcctggc tggaggaaat tgctcgtgct ttgatacccg gacgaatgcg
     7381 ttgcaaaccg gaaacgatca cccgatcgcc agcctgcaag ccagaggtga caacccactg
     7441 gtcgccgatg gctttgctgg cttcaatttc gcgtagctgc acaacatcgt ctttatccag
     7501 aatgagcgcc gttgctttac cctgggcgtt gtgggtgacg ccttcctgcg gcaccagtaa
     7561 tacattctgg cggctacctt catccactaa tgccgtgacg tacatgccag gcagcaagtc
     7621 accatttggg ttggggaaaa tcgcccgtaa cgtcacggag cccgtggttt catccaccgt
     7681 cgggtcggag aatttcagcg tgccggtctg gctgtagcgt ttaccatttt ccagattgag
     7741 ctgtactggc gtactgccct gaacctgttt gatttgccca ctggcgacct cttctttcat
     7801 gcgtaagaaa tcttgcaccg actgcgtgag atcgacataa atcgggtcca gacgttgtac
     7861 ggtaaccagc gaatctgcct gattagcggt aacgagtgcg ccgacggtca ccgacgattt
     7921 cccgctgacg cccgtaatcg gcgaggtgac attcgcgtat tgcagattga tcgtcgcctg
     7981 ttcaacagcc gctttggcga cggtgacatt ggcttctgct tcattcaact gggtgcgcgc
     8041 ggtgtcgtaa tcctgacggc taacgtagtt ggtcttcagc aacgatgcct ggcggttaaa
     8101 ggtgatgcgg gcattgctgg cggtagagag cgctttcgcc agcgagcctt tggcggagtt
     8161 tagctcggcc tgtaaaggtg caggatcaat ctgatacagc gaatcgccct ggttcacttt
     8221 atcgccttcg ataaagttgc gtttaatgat aataccgccc acctggggac gtatctcggc
     8281 aacttcataa ggaacggttc taccgggcaa ttcgctcaac acattgaccg aaccggggga
     8341 gagtgtgacg acaccgacct caggcgtcat ggcggcggcg ttttccgccg atttgtcatc
     8401 gcaggcggtg agcatcgcgc cgcagaataa caacggtatt aacagctttc ttcttctgtt
     8461 cattttagtc cctgaaaatt cttgagaaat aacggttctt taaattgcgc gcgaggagag
     8521 atatgaggga tttacagacc agcggcatag tggggttgtc agccagtaag gtgggataca
     8581 ggtatagtga tcgacatggt gaggtcaacg acaaaaaaaa tgttgccgtt ctgccaacag
     8641 ttcctgccag cattcgggca acgaagggtt ctactggtgg atacacatac caggggaata
     8701 aagtcgtttt agcctctcct ttagtaatca ccgggggtaa tgaaatcagc atctgcatcc
     8761 ctcgtcatgc cagccatcaa tttcagttgc ttatgtcctg actaaaaata agatgtgata
     8821 cccagggtga cgatgtcgct catacgtctt agtttcagct tgtacataat gttgaatttc
     8881 tgaatcttta atgtttgttg cgaaatattg agcgtcgacg tgatattgct ttcattttta
     8941 tttttcagaa tcagttgcat aattttgaac tgattatgtg aaaaacataa ttgtgaattc
     9001 ttatggggca agtgtttacc ataagtaatc tcaagaagat ttttgatact ttctttgcgg
     9061 ctaacaaaat aaataggcgc tttagctttt agtttactga tgtgataagg tgccaaaaca
     9121 ataattctct cggcatctaa tttctccaga aatttaatcg cttcttcatc aaggatatga
     9181 ttgtgatagg tatcaatgat aaccttgaag ggtttattgc ctactttttt gatctctgac
     9241 agggaattga tttttatcat ttcgtgatta tctttcaact gccaaaagcc ctgtaaaaga
     9301 aaagaatctt tcgtcatgag aaaaatcata acttgctcct tagccgttat cgtttcgaac
     9361 atgtcatcct tttcattatt tacatccttg tccgaatcgt tgttcaatat agtaaacgcc
     9421 tataagaaat ttgcccttcg tgaactaata cgtctattaa cactaatcaa tacttcagat
     9481 ttatccatca cgcactccat atattgatcc taagtaagat tcctggttgt tatcagtttg
     9541 taaacagtaa acaaaaagtt aacgtttgcg gattactgcc caagaataag ttatcaataa
     9601 ccagtttgtg atctctgaag aatattacta aagttaaaat gtaatccgat ttaaatatcg
     9661 agtctccttg tttcgactta agctggcaat tggattgcca gctttctttt aacgcattga
     9721 aattacctga gtaaataacg cattcatgtc ttcaggtttt tatatagcgt ctggagacac
     9781 ggatatttat gcaatgtaat caatgccagt tgcaaaaaaa tgaacccgga ttacttattt
     9841 aaccgcccat agcatcaacg cttacggaac tctttgttca ctttcccact gcacttttaa
     9901 aacattaaac ctgactacgg aaaatatcag ccatgataat gtttgaaatg gctaatttgc
     9961 catggagtga aaaaaattag atgaaattca gtaggttgaa ataatcacta gcaggtaatt
    10021 atttcaatga tagtgcgcaa ttgatctaca acgctgcgta gcggagagag tattaatcgg
    10081 atcatagtca catcaagtga ctatgatccg ggtgacaacc gggataatta ttgctgctta
    10141 acgaacaaac tggcgaagct gaacaggctg gcggcgctaa atatcagttc aattcccacc
    10201 agtgtggaaa ccagcgttac agacaccatc ggcgttgcac caaggaatat ccaggcaatg
    10261 acgatatcca gcacaccaat aacgagctgt agccagctgc ctttcattga acgctgacga
    10321 taccaactca tcaggcgaat aacccctgca acacagaaca aaccggcaat aaatgccgca
    10381 atggcaaaaa tgcccagctc cggtgcgcgg atgaagaaat agccgatcaa taaataggcg
    10441 actgcgacga ggaaaccgga taataccggc cagaaattat gactgcggtt gctgaataac
    10501 ccgacaataa gcgcaatgcc cgagcagatt aataatgcac ccactactgt gcttaaaata
    10561 tcgccagaga cgaacgggaa actgatacac agcaacccga cgataaacaa cagcacggca
    10621 ataaactgga ttgctctgcg atgtttttta agcatctcca gatcaaactt caaaattgtt
    10681 gccttatcta tatataacat agaaccaccc tataaaatta agaagaaaat cccctgctat
    10741 caatctatgc caaaaacgcg tctaagaatg cagtcgattt aataaaaatt tcctaattac
    10801 agtatctgat gcatctgtaa ctcattgtat tgaaataaaa atatctgatt ttgatatttt
    10861 ctatcaacat gacatataca gaaaaccagg ttataacctc agtgtcgaaa ttgattcgtg
    10921 acggctcttt cactttatag ttgaggatat tacgatgaaa aaagtattag gcgttattct
    10981 tggtggtctg cttcttctgc cagttgtaag caatgcagcg gatgcgcaaa aagcagctga
    11041 taacaaaaaa ccggtcaact cctggacctg tgaagatttc ctggctgtgg acgaatcctt
    11101 ccagccaact gcagttggtt ttgctgaagc gctgaacaac aaagataaac cagaagatgc
    11161 ggttttagat gttcagggta ttgcaaccgt aaccccagct atcgttcagg cttgtactca
    11221 ggataaacaa gccaacttta aagataaagt taaaggcgaa tgggacaaaa ttaagaaaga
    11281 tatgtaattc cgggaatgcg ttacatcgta cttccttgca tattgaacag gccggaatat
    11341 cttctttaaa agcagctatt cctcctgttc atatataatc tctatattga atgggttaca
    11401 aaatgaatat ttcatctctc cgtaaagcgt ttatttttat gggcgctgta gcggctttgt
    11461 cactggtgaa cgcacaatct gcgctggcag ccaatgaatc cgctaaagat atgacctgcc
    11521 aggaatttat tgatctgaat ccaaaagcaa tgaccccggt tgcatggtgg atgctgcatg
    11581 aagaaacagt atataaaggt ggcgataccg ttactttaaa tgaaaccgat ctcactcaaa
    11641 ttcctaaagt gatcgaatac tgtaagaaaa acccgcagaa aaatttgtat accttcaaaa
    11701 atcaagcatc taatgacttg ccgaattaat gaggtacaag taaaaaggag tagcaagttg
    11761 agccatcttg ctgctccttt ttgcattttt atatgacagc agaatttatt atacgtctta
    11821 tactcgcggc aattgcctgt ggcgctattg gcatggaaag gcaaatgcgc ggcaaaggag
    11881 cagggttacg cacacatgta ttaattggca tgggaagcgc cctgtttatg attgtttcga
    11941 aatatggttt tgctgacgtg ctgtctttag atcacgtcgg actcgacccc agccgtattg
    12001 ctgctcaggt ggtgacgggc gtcgggttta tcggtgcagg taacattctc gttcgtaacc
    12061 aaaatattgt aggtctgacg acggcagcgg atatctgggt gaccgccgcc ataggtatgg
    12121 ttattggcag cggtatgtac gaactgggta tttatggttc agtgatgacc ttgttggtgc
    12181 tggaagtctt ccatcaatta accttccgcc tgatgaacaa aaattaccat ttacagctga
    12241 cattagtgaa cggtaatacg gtatcaatgc tcgactggtt taagcagcaa aaaataaaaa
    12301 cggatttagt ttcgttgcag gaaaatgaag atcatgaagt ggtcgccatt gatatccagc
    12361 ttcatgccac aacgtcgata gaagacctgt tgcgattatt aaaaggtatg gcaggggtga
    12421 aaggcgtttc aattagctaa tctgtgtggc agcgtagcca gactcaccgt aagcctgaaa
    12481 ttcacaccag ataatcaata tgctgatggc gtaccagctc attgatccgc ttaagattga
    12541 ggatcatcat gatattgtgt ttatggcagt agaacgtttt tagcgatatt ttcagtttct
    12601 ccagaatatc ttccgttgtc atttgattcg caatgcagct cagaacctga tgttgcttgc
    12661 gcgaaagtga cacattcgct tcaggcacag agcagtaact gccattgatg agtgcgacaa
    12721 aatcaatgat agtgatagtc cgcggaacaa aggtcaccgg tactttcccc agacagcgtt
    12781 taatattaaa gggggagaaa ataatcacat ggacaggttt taatcgttca atttgagtga
    12841 gaaaattaga atgaaataca ttattcatta atgtatcaat aatgacgaag gcattctgat
    12901 gcaacattac gtcgatctct tcttcgttct gtatatgaac gacattacct ttactcagaa
    12961 tgtttttcat cgcggtgaag aacat
//
LOCUS       DAPOAV010000104        12765 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.104, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000104 DAPOAV010000000
VERSION     DAPOAV010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12765
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.104"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(96..353)
                     /locus_tag="RN951_003736"
     CDS             complement(96..353)
                     /locus_tag="RN951_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528677.1"
                     /translation="MQKPLPVRWLIIQGLTENEHCGIQAYACNTESQEDLYAEVPLVG
                     RLTGIEEVKVEAIAMSKLHNMSFPPYMGHSAAVIFHLIYLS"
     gene            476..2444
                     /locus_tag="RN951_003737"
                     /pseudo
     CDS             476..2444
                     /locus_tag="RN951_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415220.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase"
     gene            2441..3760
                     /gene="potE"
                     /locus_tag="RN951_003738"
     CDS             2441..3760
                     /gene="potE"
                     /locus_tag="RN951_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine-ornithine antiporter"
                     /protein_id="HDX2528678.1"
                     /translation="MSQAKSNKMGVVQLTILTMVNMMGSGIIMLPTKLAEVGTISIIS
                     WLVTAVGSMALAWAFAKCGMFSRKSGGMGGYAEYAFGKSGNFMANYTYGVSLLIANVA
                     IAISAVGYGTELLGASLSPVQIGLATIGVLWICTVANFGGARITGQISSITVWGVIIP
                     VVGLCIIGWFWFSPTLYVDSWNPHHAPFFSAVGSSIAMTLWAFLGLESACANTDVVEN
                     PERNVPIAVLGGTLGAAVIYIVSTNVIAGIVPNMELANSTAPFGLAFAQMFTPEVGKV
                     IMALMVMSCCGSLLGWQFTIAQVFKSSSDEGYFPKIFSRVTKVDAPVQGMLTIVIIQS
                     GLALMTISPSLNSQFNVLVNLAVVTNIIPYILSMAALVIIQKVANVPPSKAKVANFVA
                     FVGAMYSFYALYSSGEEAMLYGSIVTFLGWTLYGLVSPRFELKNKHG"
     gene            3836..3985
                     /locus_tag="RN951_003739"
                     /pseudo
     CDS             3836..3985
                     /locus_tag="RN951_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            4109..4759
                     /locus_tag="RN951_003740"
     CDS             4109..4759
                     /locus_tag="RN951_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001208812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2625 domain-containing protein"
                     /protein_id="HDX2528679.1"
                     /translation="MREMNQLVNTEDSAWPIIQNWLKDATNHTELLPVNKDLAETALY
                     QLQVTTKSPMGALVYGSGGLLIDNGWLRIAGSGHPRLPRDPVSWTQRPEFAGVRALPI
                     ADDVAGGIFALNGGDLGEDTGCVYYFAPDTLNWESLEVGYSEFLQWALSGDLDTFYEN
                     VRWQQWREDVIKLSATEAFTFYPFLWVQSEEARTRKVISLTELWEMQYQMKETFTQ"
     gene            complement(4800..5294)
                     /locus_tag="RN951_003741"
     CDS             complement(4800..5294)
                     /locus_tag="RN951_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528680.1"
                     /translation="MKTNRSLVVIVSLITATLLLTACAQPEQSSLAGDWLLTPKDKTR
                     GLTGSIAVNIAPFRCKTNCRGDNLPDNTRRWQLSGGNEKELTYLHNMSAQEKVGLNPG
                     WQCYTSFFMRVCQGKPGTRPIVNEDYVSESGFFGSMMHVGIIELRRCQSENCQQELKA
                     INTH"
     gene            complement(5508..7148)
                     /gene="pgm"
                     /locus_tag="RN951_003742"
     CDS             complement(5508..7148)
                     /gene="pgm"
                     /locus_tag="RN951_003742"
                     /EC_number="5.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-glucose phosphate-specific
                     phosphoglucomutase"
                     /protein_id="HDX2528681.1"
                     /translation="MAIHNRAGQPAQQSDLINVAQLTAQYYVLKPEAGNAEHAVKFGT
                     SGHRGSAARHSFNEPHILAIAQAIAEERAKNGITGPCYVGKDTHALSEPAFISVLEVL
                     AANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPP
                     NGGPADTNVTKVVEDRANALLADGLKGVKRISLDEAMASGHVKEQDLVQPFVEGLADI
                     VDMAAIQKAGLTLGVDPLGGSGIEYWKRIGEYYNLNLTIVNDQVDQTFRFMHLDKDGA
                     IRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMNPNHYLAVAINYLFQ
                     HRPQWGKDVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEES
                     AGASFLRFDGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAKRFGAPSYNRLQA
                     AATSAQKAALSKLSPEMVSASTLAGDPITARLTAAPGNGASIGGLKVMTDNGWFAARP
                     SGTEDAYKIYCESFLGEEHRKQIEKEAVEIVSEVLKNA"
     gene            complement(7174..7719)
                     /gene="seqA"
                     /locus_tag="RN951_003743"
     CDS             complement(7174..7719)
                     /gene="seqA"
                     /locus_tag="RN951_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation negative regulator SeqA"
                     /protein_id="HDX2528682.1"
                     /translation="MKTIEVDDELYSYIASHTKHIGESASDILRRMLKFSAASQPAAP
                     VTKEVRVASPAIVEAKPVKTIKDKVRAMRELLLSDEYAEQKRAVNRFMLLLSTLYSLD
                     AQAFAEATESLHGRTRVYFAADEQTLLKNGNQTKPKHVPGTPYWVITNTNTGRKCSMI
                     EHIMQSMQFPAELIEKVCGTI"
     gene            7904..8668
                     /gene="ybfF"
                     /locus_tag="RN951_003744"
     CDS             7904..8668
                     /gene="ybfF"
                     /locus_tag="RN951_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HDX2528683.1"
                     /translation="MKLNIRAQTAQNQHNNSPIVLVHGLFGSLDNLGVLARDLVNDHN
                     IIQVDMRNHGLSPRDPVMNYPAMAQDLVDTLDAQQIDKATFIGHSMGGKAVMALTALA
                     SDRIDKLVAIDIAPVDYHVRRHDEIFAAINAVSESDAQTRQQAAAIMRQHLNEEGVIQ
                     FLLKSFVDGEWRFNVPVLWDQYPHIVGWEKIPAWDHPALFIPGGNSPYVSEQYRDDLL
                     AQFPQARAHVIAGAGHWVHAEKPDAVLRAIRRYLND"
     gene            8808..9101
                     /gene="ybfE"
                     /locus_tag="RN951_003745"
     CDS             8808..9101
                     /gene="ybfE"
                     /locus_tag="RN951_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415211.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA regulated protein"
                     /protein_id="HDX2528684.1"
                     /translation="MAKEQTDRTTLDLFAHERRPGRPKTNPLSRDEQLRINKRNQLKR
                     DKVRGLKRVELKLNAEAVEALNELAESRNMSRSELIEEMLMQQLAALRSQGIV"
     gene            9241..9771
                     /gene="fldA"
                     /locus_tag="RN951_003746"
     CDS             9241..9771
                     /gene="fldA"
                     /locus_tag="RN951_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldA"
                     /protein_id="HDX2528685.1"
                     /translation="MAITGIFFGSDTGNTENIAKMIQKQLGKDVADVHDIAKSSKEDL
                     EAYDILLLGIPTWYYGEAQCDWDDFFPTLEEIDFNGKLVALFGCGDQEDYAEYFCDAL
                     GTIRDIIEPRGATIVGHWPTAGYHFEASKGLADDDHFVGLAIDEDRQPELTAERVEKW
                     VKQISEELHLDEILNA"
     gene            9981..10067
                     /gene="uof"
                     /locus_tag="RN951_003747"
     CDS             9981..10067
                     /gene="uof"
                     /locus_tag="RN951_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001491546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fur leader peptide"
                     /protein_id="HDX2528686.1"
                     /translation="MIRIISRANSVTSSNEVNRLVTGQIPHD"
     gene            10060..10506
                     /gene="fur"
                     /locus_tag="RN951_003748"
     CDS             10060..10506
                     /gene="fur"
                     /locus_tag="RN951_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric iron uptake transcriptional regulator"
                     /protein_id="HDX2528687.1"
                     /translation="MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLI
                     DMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEF
                     SDDSIEARQREIAAKHGIRLTNHSLYLYGHCAEGDCREDEHAHEGK"
     gene            complement(10590..10916)
                     /locus_tag="RN951_003749"
     CDS             complement(10590..10916)
                     /locus_tag="RN951_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528688.1"
                     /translation="MKKLILIAIMASGLVACAQSTAPQEDSRLKEAYSACINTAQGSP
                     EKIEACQSVLNVLKKEKQHQQFADQESVRVLDYQQCLRATQTGNDQAVKADCDKVWQE
                     IRSNNK"
     gene            complement(10966..12372)
                     /gene="chiP"
                     /locus_tag="RN951_003750"
     CDS             complement(10966..12372)
                     /gene="chiP"
                     /locus_tag="RN951_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitoporin"
                     /protein_id="HDX2528689.1"
                     /translation="MRTFSGKRSTLALAIAGVTAMSGFMAMPEARAEGFIDDSTLTGG
                     IYYWQRERDRKDVTDGDKYKTNLSHSTWNANLDFQSGYAADMFGLDIAAFTAIEMAEN
                     GDSSHPNEIAFSKSNKAYDEDWSGDKSGISLYKAAAKFKYGPVWARAGYIQPTGQTLL
                     APHWSFMPGTYQGAEAGANFDYGDAGALSFSYMWTNEYKAPWHLEMDEFYQNDKTTKV
                     DYLHSFGAKYDFKNNFVLEAAFGQAEGYIDQYFAKASYKFDIAGSPLTTSYQFYGTRD
                     KVDDRSVNDLYDGTAWLQALTFGYRAADVVDLRLEGTWVKADGQQGYFLQRMTPTYAS
                     SNGRLDIWWDNRSDFNANGEKAVFFGAMYDLKNWNLPGFAIGASYVYAWDAKPATWQS
                     NPDAYYDKNRTIEESAYSLDAVYTIQDGRAKGTMFKLHFTEYDNHSDIPSWGGGYGNI
                     FQDERDVKFMVIAPFTIF"
BASE COUNT         3156 a         3083 c         3148 g         3378 t
ORIGIN      
        1 tcatcattaa ataaattaag attgatcatt ttttattgat caccttcaca gttcaaccgt
       61 atttcctgga tagaatatct tcaccttcat tcacatcagg aaaggtaaat taaatggaaa
      121 ataacagccg cactatgccc catataaggc ggaaaactca tattatgaag tttgctcatc
      181 gcaatagctt cgactttcac ttcttcaatg cccgttagtc taccgactaa gggcacttca
      241 gcgtacaggt cttcctgact ctctgtatta caggcatatg cctgtattcc gcagtgctca
      301 ttctctgtta acccttgtat tatcagccac ctgactggta agggtttctg cattctgaaa
      361 aaagcaatct acctgattta tttatcagcg gggtaacttt gcttttttcc ggcacgatcg
      421 atttctcatt cgagaaattg aggacctgct attacctaaa ataaagagat gaaaaatgtc
      481 aaaattaaaa attgcggtta gtgattcttg cccggactgt tttaccacgc agcgagaatg
      541 tatctacatt aatgaaagtc gtaatatcga tgtggcggca atagttttat cgctcaacga
      601 tgttacatgc ggaaaactcg atgaaatcga tgccacgggt tatggcatcc cggtatttat
      661 tgctactgaa aatcaagaac gtgtacccgc agagtatttg ccccgtattt cgggtgtctt
      721 tgagaattgc gaatcgcgac gagaatttta tggtcgccag ttagaaaccg ctgccagcca
      781 ttatgaaact caactgcgcc cacctttctt ccgcgcactg gtcgattatg tcaatcaagg
      841 taacagcgcg tttgattgcc ctggtcatca gggcggcgaa tttttccgtc gccatccggc
      901 ggggaatcag tttgtggaat actttggtga ggcgctgttc cgtgccgact tgtgcaacac
      961 cggtttatct ggaaacggca cgtaacccgt atggctttat cggtggcatt gatgcgcact
     1021 gttttgaaga aagttacctg cgtgagctga tcgcggaagt cgcaccgcag cgggcaaaag
     1081 aggctcgtcc tttccgcctc gctgtgattc agttaggcac ctacgacggt acgatttata
     1141 acgcccgcca agtggtggat aaaattggtc atctgtgtga ctacatcctg tttgactcag
     1201 catgggtcgg ctatgaacag tttattccga tgatggcgga ctgttcgccg ctgttgctgg
     1261 atcttaatga gaacgatccg ggtattctgg ttacgcaatc tgtgcataaa caacaggctg
     1321 gtttttctca gacttcacaa attcataaaa aagacagcca catcaaaggg caacagcgtt
     1381 atgtaccgca caaacgcatg aacaacgcct ttatgatgca cgcctccacc agcccgttct
     1441 atccgctgtt tgccgcactg gatatcaacg ccaaaatgca tgaaggtgtc agcggtcgta
     1501 atatgtggat ggattgtgtg gtaaatggca ttaatgcccg caaactgatc ctcgataact
     1561 gtcagcatat tcgtccgttc gtacctgaac tggtggatgg taaaccctag cagtcgtatg
     1621 aaacagcgca aattgcggtt gatctgcgct tcttccagtt tgtaccaggg gaacactggc
     1681 attcttttga aggctatgca gagaatcaat actttgtcga tccatgcaaa ctgttgctga
     1741 caaccccagg tattgatgca cgtaacggcg aatatgaagc gttcggtgta cccgcgacga
     1801 ttcttgctaa cttcctgcgc gaaaatggcg tagtgccgga aaaatgcgat cttaactcca
     1861 tcctcttcct gctgactccg gcagaagata tggccaaact tcagcaactt gttgccctgc
     1921 tggtacgctt cgaaaaactg cttgagtccg acgcgccatt agcagaagtg ctaccttcca
     1981 tctacaaaca gcatgaagag cgctacgccg gttataccct gcgtcagttg tgtcaggaaa
     2041 tgcatgattt gtatgcccgc cacaacgtga aacaactgca aaaagagatg ttccgtaagg
     2101 agcacttccc acgcgtcagc atgaatccgc aagaagccaa ctacgcctat ttacgcggtg
     2161 aagtggaact ggttcgtctg ccggatgcag aaggccgtat cgctgccgaa ggtgcgcttc
     2221 cttatcctcc gggtgtgctg tgtgttgttc cgggtgaaat ctggggtggt gctgttctgc
     2281 gttacttcag cgctctggaa gaagggatca acctgctgcc aggttttgca ccggagctgc
     2341 agggtgtcta tatcgaagaa catgatggtc gtaagcaagt ttggtgctat gtcatcaagc
     2401 ctcgtgatgc gcaaagcacc ctgttgaaag gggaaaaatt atgagtcagg ctaaatcgaa
     2461 caaaatgggc gtcgttcagt taaccatact gacgatggtc aacatgatgg gctccggtat
     2521 catcatgctg ccgacaaagc ttgccgaagt cgggacaatc tcaattatct cctggctggt
     2581 gacagccgta ggctcaatgg cactggcatg ggcattcgca aaatgcggta tgttcagccg
     2641 taaatcaggc ggtatgggcg gttatgccga gtatgctttc ggtaaatccg gtaactttat
     2701 ggcgaactat acctacggcg tctcactgct gattgctaac gtcgcgattg ctatttcggc
     2761 ggttggttac ggcaccgaac tgctcggcgc gagtttgtcg ccagtgcaga ttggtcttgc
     2821 gaccatcggg gtgctgtgga tttgtaccgt ggctaacttt ggtggtgcgc gcattaccgg
     2881 gcaaatcagt agcattaccg tgtggggggt cattattccg gtcgtcggtc tgtgcattat
     2941 tggctggttc tggtttagcc cgacgctgta cgttgattcc tggaatccgc atcatgcacc
     3001 gttcttcagt gcggtaggtt cttccatcgc tatgacgctg tgggcttttc ttggtctgga
     3061 gtctgcgtgt gcgaatactg atgtagtgga aaacccggaa cgtaatgtgc caatcgcggt
     3121 actcggcggt acgttaggtg cggcggtgat ttatatcgtc tccaccaacg tgattgccgg
     3181 gattgtgcca aatatggagc tggcaaattc aacggcacca tttggtctgg ccttcgcgca
     3241 gatgttcacg ccggaagtgg gtaaagtcat tatggcgctg atggtgatgt cctgctgcgg
     3301 ttcgctactt ggctggcagt tcaccattgc ccaggtgttt aaatcttcat ctgatgaagg
     3361 ctacttccct aaaattttct cccgtgtaac caaagtggat gcaccggtgc agggaatgtt
     3421 gaccattgtg attattcaga gtggattggc actgatgacc attagcccgt cgctaaacag
     3481 tcagttcaac gtgctggtta acctggccgt ggtgaccaat atcattccgt atattctgtc
     3541 aatggcggca ttagtcatta ttcagaaggt cgctaatgtg cccccctcaa aagcgaaagt
     3601 tgcaaacttt gttgcttttg ttggcgcgat gtatagcttt tatgcgctgt actcatccgg
     3661 ggaagaagcc atgctgtacg gttccatcgt gaccttcctt ggttggacac tgtatggtct
     3721 ggtatcacca cgctttgaac tgaaaaataa acacggttaa taaaacaaag taaaaaaggg
     3781 cgattgaatg atcgcccttt ctgtttgttg gcaaatagtt cgttatttat gccgcatccg
     3841 gcagatgtag ggtctaaacg cgatcgaaca cagcaactat ttgcgtaatt atatggggca
     3901 tctgcgacaa aaactggaac aggatccggc ccggcctcgc cattttatta ctgaaaccgg
     3961 tattgggtat cggtttatgc tttgaaaaaa gtggcaatgt atggataaag tcatttttta
     4021 ttcaaatata aggaacttaa tatttaaaaa atgttccata caattcctca tcataaatga
     4081 caccgtagca cacaaggagc aagtagcgat gcgtgaaatg aatcagttag taaatactga
     4141 agattcagcc tggccaataa tccagaactg gttaaaagac gccacaaacc ataccgaact
     4201 cttaccggtt aataaagatt tagccgaaac cgcactttat caattacagg tgacaacaaa
     4261 atcaccgatg ggtgcgcttg tctatggctc cggaggtctg ctgattgata atggttggtt
     4321 acgcatagca ggatctggtc acccccggtt gccacgagat ccagtaagtt ggacacaacg
     4381 ccctgaattc gcaggcgtgc gggctttacc catcgctgac gatgtcgcag ggggaatttt
     4441 tgctcttaat ggtggcgatc ttggggaaga tactggctgc gtttattatt ttgcgccaga
     4501 tacgctgaat tgggaaagtc tggaagttgg atattctgag tttcttcagt gggcattatc
     4561 cggtgattta gataccttct atgaaaatgt acgatggcag caatggcgag aagacgtaat
     4621 aaaattatcg gcaacggaag ccttcacgtt ctaccctttc ttatgggtac aaagtgaaga
     4681 agcaagaaca agaaaagtta tttcgcttac tgaactctgg gaaatgcagt atcaaatgaa
     4741 agaaacattc acgcaataag acatgttcag gtccgggttt cattcccgga ctcactattt
     4801 taatgtgtat ttatcgcttt caattcttgc tggcaatttt ctgactggca gcgtcgtaac
     4861 tcaataatcc cgacatgcat catcgagcca aaaaatccgc tttcgctgac ataatcctca
     4921 ttgactatcg gtcgagtgcc gggcttgccc tggcaaaccc gcataaaaaa tgaggtgtag
     4981 cattgccaac cgggatttaa accgaccttt tcttgtgctg acatattatg aagataagta
     5041 agttcttttt cgttcccgcc tgacaactgc cagcggcggg tattatcagg taagttatca
     5101 ccacggcaat ttgtcttaca ccggaaaggt gcaatattta ccgcaatgct acccgttaat
     5161 cctctggttt tatctttagg ggtcagtaac cagtcgccag ctaatgatga ttgttcaggt
     5221 tgggcgcatg cagtcagcag taatgtggcg gtaattagtg acactatgac gaccagactc
     5281 ctgttggtct tcattgggat ttccttgagc tactcagttt gttgacaaag tgttcgttgt
     5341 ttttgccgga tgcggcgtga acgccttatc cggcctacaa aatcgcttaa attcaatata
     5401 ttgcaccatc ctcgtaggcc tgataagcgt agcgcatcag gcaattctgt gtttgtcata
     5461 cgtaaaaaag ggcgatcttg cgaccgccct ttttttatta aatgtgttta cgcgtttttc
     5521 agaacttcgc taacaatctc aaccgcttct ttctcaatct gcttgcgatg ttcttcaccg
     5581 aggaagcttt cgcagtagat cttatatgcg tcttccgtgc ctgacggacg cgcggcgaac
     5641 cagccgttgt cagtcatcac tttcagaccg ccaatagaag caccgttgcc cggagcagca
     5701 gtcaggcgcg cggtgatcgg gtcacctgcc agggtgctgg cgctcaccat ttccggagac
     5761 agcttagaca gcgccgcttt ttgtgcggaa gtcgcagctg cctgcaaacg gttgtagctc
     5821 ggcgcaccaa agcgttttgc cagttcgttg tagtgttcct gcgggttctt accggtgaca
     5881 gcggtgattt ccgccgccag cagacacatg atgatgccgt ctttgtcggt ggaccacggc
     5941 gtgccgtcga aacgcaggaa ggaagcccct gcactctctt cgccgccaaa gccgaagctg
     6001 ccgtcgaaca gaccatcgac aaaccatttg aaacctaccg ggacttctac cagtttacgg
     6061 cccaagtcgt tgaccacacg gtcgatcatc gcagatgaaa ccagcgtttt accgacggca
     6121 acatctttgc cccactgcgg acgatgctgg aacaggtaat tgattgccac cgccaggtag
     6181 tggttcggat tcatcaaacc tgccggagtg acgataccgt gacggtcata atccgggtcg
     6241 ttagcaaacg ccagatcgaa cttatcacgc agtgccagca ggcccgccat cgcacactcg
     6301 gaggagcagt ccatacggat cgcgccgtct ttatcaaggt gcataaagcg gaaggtttga
     6361 tcgacctgat cgttaacgat agtcaggttg aggttgtaat actcgccaat acgcttccag
     6421 tattcgatac cggaaccgcc cagcggatca acgcccagcg tcaggcccgc tttctgaatc
     6481 gcggccatat caacgatatc ggccagacct tccacgaacg gctgcaccag atcctgctct
     6541 ttcacatgac cggatgccat cgcttcgtcg agggagatac gcttcacgcc tttcaggcca
     6601 tcggccagca gtgcgttggc cctgtcttcc accactttag tgacgttggt atcagccggg
     6661 ccaccatttg gcggattgta tttgattcca ccatcttccg gcgggttatg ggacggtgta
     6721 atcacgatac cgtctgccag cgggccacct tttttattgt gaaccaggat ggcattggaa
     6781 acggcaggcg tcggggtgaa gccattgttt tcctgcacaa tgacatcaac gccgttcgct
     6841 gccagcactt ccagaacgga aatgaatgca ggttcggaca gggcgtgagt atctttaccc
     6901 acatagcaag ggccagtgat gccgtttttc gcacgttctt cagcaattgc ctgagcgatc
     6961 gccagaatgt gcggctcgtt aaagctgtgg cgcgctgcac tgccacggtg accggaagta
     7021 ccgaatttca ccgcgtgctc cgcattccct gcttctggtt tcagtacata atattgcgcc
     7081 gtcagttggg cgacgttaat caaatcactc tgttgtgcag gttggcctgc acgattgtgg
     7141 attgccattg ctttgtcctt tgtctgcaac gttttagata gttccgcaaa ccttctcaat
     7201 caattccgcc gggaattgca tcgactgcat gatgtgttcg atcatgctgc atttacggcc
     7261 ggtgttggtg ttggtgatca cccaatacgg cgtgcctggc acatgtttcg gcttggtctg
     7321 attaccattt ttcagcagcg tttgttcatc tgccgcaaag taaacgcgtg tacgaccgtg
     7381 caacgattcc gttgcttcgg caaacgcctg ggcgtcaaga gaatatagtg tagacaacag
     7441 cagcataaag cgattgaccg ctcgcttttg ctctgcgtat tcatccgaaa gcagaagttc
     7501 acgcattgcg cgaaccttgt ctttaatcgt tttgaccggc ttcgcttcga cgatagcagg
     7561 tgacgcaacg cgaacctctt tcgtcaccgg agcagcaggc tgtgatgcgg cggaaaattt
     7621 caacatacgc cgtaaaatgt cggatgcgct ctcgccgata tgcttagtgt ggctggcaat
     7681 atagctgtag agttcatcat caacttcaat cgttttcatc ttaatccagt gcagtgtctt
     7741 agctgaatac aagtcgccag gagtatatga ataaatcccg gcagcggata gcgtcaagcc
     7801 tggcttgcag aaaaactcgg aataaacctt atttgttgca gccctgtggc acaatggtca
     7861 acataatacc ctaacccgac aacgcgaaaa aaagaacttt gccatgaaat tgaatatccg
     7921 cgcgcaaact gcacaaaacc agcacaataa ttctcccatc gttcttgtcc acggtctgtt
     7981 tggcagcctc gacaaccttg gcgtactggc tcgcgatctg gtaaacgatc acaatatcat
     8041 ccaggttgat atgcgtaacc acggtctttc accgagagat ccggtaatga attacccggc
     8101 gatggcgcag gatcttgttg atactctgga tgcacagcag atcgacaaag caacatttat
     8161 cggtcactcc atgggcggta aagcggtaat ggcacttact gcactagcct ccgatcgcat
     8221 cgataaactg gtggcgatcg atatcgcgcc ggtcgactat cacgtacgcc gtcatgatga
     8281 gatttttgcg gctatcaacg cggtcagtga atcggacgca caaactcgcc agcaagcagc
     8341 agcaataatg cgccagcatc ttaatgaaga aggggtgatt cagtttctgc tgaaatcttt
     8401 tgttgacggg gagtggcgct ttaacgtgcc ggtattgtgg gatcagtatc cgcatattgt
     8461 aggttgggag aaaatcccgg catgggatca ccctgccctg tttatccctg gcggcaattc
     8521 tccgtatgtt agcgagcagt accgtgatga tttactggct caatttccac aggcacgggc
     8581 gcatgtgatt gcaggcgcgg gtcactgggt ccatgctgaa aaaccggatg cggtattacg
     8641 cgctatccgt cgctatctca atgattaacg caactgatta aaaacccagc gtccgcgtcg
     8701 ctttccgcgc gtgggcgttg gcgtgactca tcgcgctgat gtattatggc gcgctatcca
     8761 tccgggcaga ggcctggctg attgtttccc ccgaagtcac caagatcatg gccaaagaac
     8821 aaacggaccg tacgacatta gatctgttcg cgcacgagcg tcgaccggga cgaccgaaaa
     8881 ctaatccgct ttcgcgcgat gaacagctgc gtattaataa acgcaaccag ctaaaacgcg
     8941 acaaagtacg tggccttaag cgtgtcgaac tgaagctgaa cgcggaagct gtcgaggcgc
     9001 tgaacgagct ggcggagtcg cgcaatatga gccgtagcga actgatcgaa gagatgttaa
     9061 tgcagcaact ggcggcgctg cgtagtcagg gcatcgttta aatttccact ttcatgtagc
     9121 acagtgtgca gtcctgctcg tttgctgatt ccgcaagact gcctgttctg ctatgattgc
     9181 ctttatccgt gggcaatttt ccacccccat ttcaataagt ttcaagaggt tatttcactc
     9241 atggctatca ctggcatctt tttcggcagc gacaccggta ataccgaaaa tatcgcaaaa
     9301 atgattcaaa aacagcttgg taaagacgtt gccgatgtcc atgacattgc aaaaagcagc
     9361 aaagaagatc tggaagctta tgacattctg ctgctgggca tcccaacctg gtattacggc
     9421 gaagcgcagt gtgactggga tgacttcttc ccgactctcg aagagattga tttcaacggc
     9481 aaactggttg cgctgtttgg ttgtggtgac caggaagatt acgccgaata tttctgcgac
     9541 gcattgggca ccatccgcga catcattgaa ccgcgcggtg caaccatcgt tggtcactgg
     9601 ccaactgcgg gctatcattt cgaagcatca aaaggtctgg cagatgacga ccactttgtc
     9661 ggtctggcta tcgacgaaga ccgtcagccg gaactgaccg ctgaacgtgt agaaaaatgg
     9721 gttaaacaga tttctgaaga gttgcatctc gacgaaattc tcaatgcctg atgtgatgcg
     9781 gcgtagactc atgtctacgc cgtattaata gataatgcca atcaaaataa ttgctacaaa
     9841 tttgtaactt ttgctgttgt acctgtacaa tgtcccggtg ttcaagtggc cttgccgttg
     9901 taaatgtaag ctgtgccacg tttttattaa caatatttgc cagggacttg tggttttcat
     9961 ttaggcgtgg caattctata atgatacgca ttatctcaag agcaaattct gtcacttctt
    10021 ctaatgaagt gaaccgctta gtaacaggac agattccgca tgactgataa caataccgcc
    10081 ctaaagaaag ctggcctgaa agtaacgctt cctcgtttaa aaatcctgga agttcttcag
    10141 gagccggaca accatcacgt cagtgcggaa gatttataca aacgtctgat cgatatgggt
    10201 gaagaaattg gtctggctac ggtatatcgc gtactgaacc agtttgacga cgctggtatc
    10261 gtcacccgcc acaattttga aggcggtaaa tccgtatttg aactgacaca gcaacatcac
    10321 cacgatcacc tgatctgcct cgactgcggc aaggttatcg aatttagtga tgattccatc
    10381 gaagcgcgtc agcgtgaaat tgccgcaaaa catggcattc gcctgactaa ccacagtctc
    10441 tatctttacg gtcactgtgc cgaaggcgat tgccgcgaag atgaacatgc gcacgaaggc
    10501 aaataagcca gcctgaacga gaaaagccaa cctgcgggtt ggctttttta tgcaagggaa
    10561 ataagaaaag cgagagttac agctctcact tatttgttat tactgcgtat ttcctgccag
    10621 actttatcac aatcggcttt caccgcctga tcatttccgg tttgcgttgc acgcagacac
    10681 tgctgataat ccagtacgcg tacactttcc tggtcggcaa actgctgatg ttgtttctct
    10741 ttcttcagca cgtttaacac gctctggcag gcttcaattt tttctggcga accttgtgcg
    10801 gtgttgatac aggcgctgta tgcctctttc agacgactgt cttcctgtgg cgcggttgat
    10861 tgcgcacaag ctaccagccc cgatgccatt atggcgatga gaatcagttt tttcatagca
    10921 aattcctcaa acgtgcggca ggcacaaaac ctgccgcgtc gggcatcaga agatggtgaa
    10981 tggtgcgatt accataaatt tcacgtcacg ctcatcctgg aagatgttgc cgtaaccacc
    11041 gccccagctt gggatgtcgg agtggttgtc gtattcggtg aaatgcagtt tgaacatcgt
    11101 gcctttggcg cgaccgtcct gaatggtata gaccgcatcc aggctgtagg cagactcttc
    11161 aatagtccgg tttttgtcgt agtacgcatc cggattgctc tgccaggtcg caggtttagc
    11221 atcccatgcg taaacgtagg aagcgccgat ggcgaagcct ggaagattcc agtttttcag
    11281 gtcatacatc gcaccgaaga agaccgcttt ttcgccgttg gcgttgaagt cagaacggtt
    11341 atcccaccag atatccaggc gaccgtttga ggaagcgtag gttggagtca tacgttgcag
    11401 gaagtatccc tgctgaccgt cagccttaac ccaggtgcct tcgaggcgca aatccactac
    11461 gtcagccgcc cggtaaccaa aggtcaacgc ttgcagccag gcggtgccgt cataaaggtc
    11521 gttgacgctg cgatcgtcaa ctttatctcg ggtaccgtag aactggtagc tggtggttaa
    11581 cgggctaccg gcgatatcaa atttgtagct ggctttggca aaatattgat cgatataccc
    11641 ttccgcctga ccaaatgccg cttccagtac gaagttattt ttgaagtcgt atttcgcccc
    11701 aaaggagtgc agataatcaa ctttggtggt tttatcgttc tgataaaact catccatttc
    11761 cagatgccac ggcgctttgt attcgttggt ccacatgtag gagaaactca acgcaccagc
    11821 atcgccgtaa tcaaaattcg ccccggcttc cgccccctga taagtacctg gcataaagct
    11881 ccagtgcggc gctaacagcg tttgaccagt tggctgaatg taacctgccc tcgcccaaac
    11941 cggaccgtat ttaaatttgg ccgcagcttt atacaggctt ataccgcttt tgtcgccgga
    12001 ccagtcttcg tcataggctt tattactttt tgaaaacgcg atttcgttcg ggtgggagct
    12061 gtcgccgttt tccgccattt caatcgccgt aaacgcagca atatcaaggc cgaacatatc
    12121 agcagcataa ccggactgaa aatcgaggtt ggcattccag gtggagtgag aaaggttggt
    12181 tttgtatttg tcgccgtcgg taacatcttt acggtcgcgt tcacgctgcc agtaatagat
    12241 accgccggtt aaggttgaat cgtcgatgaa tccttcggcg cgagcctccg gcattgccat
    12301 aaagcccgac attgctgtaa caccggcgat agccagcgcc agcgtactac gtttgccact
    12361 aaacgtacgc atgggttaat cctctttgac gtataaattg ctgcaccaaa ggtgaacagc
    12421 gaaaaaataa aaattaaaaa agtagcgttg agaaaagtct cgctgactac aggaacagac
    12481 tatttttcgc gacgcgaatt atcaatctct ttctgtaacc agaatgtaag aacatgagca
    12541 accgcacata ttttgatgat ttttgttaca aggcttaagt ttgcggttga aaggcttgca
    12601 gaagaataaa agcgtgaaat tccagcaaga tgaaagcggt tacattttat ttaattatgt
    12661 tttgttattt taaatttatt ttatggataa attgcgaagc ggaattaatt cgcgaagaaa
    12721 agcagaaaaa acgccgctga acgcggcgtt ttggattgtt tgctg
//
LOCUS       DAPOAV010000105        12508 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.105, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000105 DAPOAV010000000
VERSION     DAPOAV010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12508
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.105"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(48..329)
                     /locus_tag="RN951_003751"
     CDS             complement(48..329)
                     /locus_tag="RN951_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YehE family protein"
                     /protein_id="HDX2528690.1"
                     /translation="MNKYWLSGIIFLAYGLASPAFSSETATLTINGRISPPTCSMAMV
                     NSQPQQHCGQLTYNVDTRHQVSSPVKGVTTEVVVAGSDSKRRIVLNRYD"
     gene            complement(592..1701)
                     /gene="apbC"
                     /locus_tag="RN951_003752"
     CDS             complement(592..1701)
                     /gene="apbC"
                     /locus_tag="RN951_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310946.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster carrier protein ApbC"
                     /protein_id="HDX2528691.1"
                     /translation="MNEQSQAKSPEALRAMVAGTLANFQHPTLKHNLTTLKALHHVAW
                     MDDTLHVELVMPFVWHSAFEELKEQCSAELLRITGAKAIDWKLSHNIATLKRVKNQPG
                     INGVKNIIAVSSGKGGVGKSSTAVNLALALAAEGAKVGILDADIYGPSIPTMLGAENQ
                     RPTSPDGTHMAPIMSHGLATNSIGYLVTDDNAMVWRGPMASKALMQMLQETLWPDLDY
                     LVLDMPPGTGDIQLTLAQNIPVTGAVVVTTPQDIALIDAKKGIVMFEKVEVPVLGIVE
                     NMSVHICSNCGHHEPIFGTGGAEKLAEKYHTQLLGQMPLHISLREDLDKGTPTVISRP
                     ESEFTAIYRQLADRVAAQLYWQGEVIPGEISFRAV"
     gene            1833..3866
                     /gene="metG"
                     /locus_tag="RN951_003753"
     CDS             1833..3866
                     /gene="metG"
                     /locus_tag="RN951_003753"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HDX2528692.1"
                     /translation="MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGH
                     EVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEE
                     NRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCE
                     VCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANK
                     MQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSV
                     SFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKM
                     SKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVN
                     LASRNAGFINKRFDGVLASELADPQLYKTFTDAAEVIGEAWESREFGKAVREIMALAD
                     LANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLN
                     TELTWDGIQQPLLGHKVNPFKALYNRIDMKQVEALVEASKEEVKAAAAPVTGPLADDP
                     IQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQ
                     ALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK"
     gene            4007..7801
                     /locus_tag="RN951_003754"
     CDS             4007..7801
                     /locus_tag="RN951_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WGR and DUF4132 domain-containing protein"
                     /protein_id="HDX2528693.1"
                     /translation="MRHFIYQDEKSHKFWAVEQQGNELHISWGKVGTKGQSQIKSFSD
                     AAAVAKAELKLIAEKVKKGYVEQAKDNSLQPSQTVTGSLKVADLSTIIQEQPSFVAET
                     RAPDKNTDAVLPWLAKDIAVVFPPEVVHTTLSHRRFPGVPVQQADKLTQLRRLACSVS
                     QRDNKTATFDFSACSLEWQNTVAQAISQIDGLKTTQLPSPVMAVLTALEMKCTRYKVR
                     EDVMDQIVQEGGLEYATDVIIHLQQIDIKWDYANNVIIILPSGIAPDYLEQYSRFELR
                     LRKHLSLAEESLWQKCAQKLIAAIPHIPEWRQPLIALLLPEKPEIAHEIAQRLLGQKK
                     LPSLEWLKIVATDEHILASLEKYHEPYAIFDDYYCGAIWSATVLQEQGVAALPRFAPY
                     AASDYCADVLRHINHPFALTLLIRVAGHTKRCHDRMTKACAAFPHAAMAALTELLGQK
                     EENSWRIMLMTMLISQPALAEQVIPWLSTPAVAVLKSCQQQLTQPSNHASADLLPAVV
                     VSPPWLSKKKKSPIPVLDLAPLGIEPICYLTEEISNQLLAKYIWYSKHITVSHEESTT
                     NLLARMGFQRRIAGTYIKAPEAVVEAWLNEDYSTLLSEFKVFHSPTGHYWQLGILTTL
                     PLEKAVKAWNALTLSPHTDTEYAMLHFGLKGLPGLVNSLARYPQEALPITNYFAASEL
                     APAVARAFNKLKTLRENARSWLLKYPEHALTGLLPAALGKAGEAQDNARAALRMLTEN
                     GHQPLLQEIARRYNQPEVTDAVNALLALDPLDNHPTKIPTLPAFYQPSLWTRPVLKAN
                     AQSLPDSALLHLGEMLRFPQEEALYPGLLQVKDVCSADSLAGFAWDLFTAWQTAGAPS
                     KESWAFTALGVLGNDDTARKLTPLIRAWPGESQHKRATVGLDILAAIGSDIALMQLNG
                     IAQKLKFKALQERAKEKIADIAESRELTVAELEDRLAPDLGLDDNGSLLLDFGPRQFT
                     VSFDETLKPFVRDVSGSRLKDLPKPNKSDDETRANDAVNRYKLLKKDARTIATQQVAR
                     LESAMCLRRRWSLENFQLFLVEHPLVRHLTRRLIWGVYSAENQLLACFRVAEDNSYST
                     ADDDLFTLPEGDISIGTPHVLEISPTDAAAFGQLFADYELLPPFRQLDRNSYALTEAE
                     RNASELTRWAGRKCPSGRVMGLANKGWVRGEPQDGGWIGWMIKPLGRWSLIMEIDEGF
                     AVGMSPAELSAEQLLSKLWLWEGKAESYGWGSNSTQEAQFSVLDAITASELINDIEAL
                     FE"
     gene            7811..11443
                     /locus_tag="RN951_003755"
     CDS             7811..11443
                     /locus_tag="RN951_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HDX2528694.1"
                     /translation="MDKELPWLADNAQLELKYKKGKTPLSHRNWPGEPVPVITESIIQ
                     TLGDELLQKAEKKKNIVWRYENFSLEWQSAITQAINLIGEHKPSIPAQTMAALVCIAQ
                     NDSQQLLDEIVQQEGLEYATEVVIARQFITRCYESDPLVVTLQYQNEDYGYGYRSETY
                     NEFDLRLCKHLSLAEESCWQRCADKLIATLPGITKVRRPFIALILPEKPEIANELVSL
                     ECPRTHFHSKEWLKVVANDPTAVRKLERYWSQDIFSDREASYMSHENHFGYAASAALL
                     REQGLAAVPRLAIYAHKEDCGSLLVQINHPQVIRTLLLVADKNKPSLQRVAKYSKNFP
                     HATLAALAELLALKEPPARPGYPIIEDKKLPAQQKARDEYWRTLLQTLIASQPQLAER
                     VMPWLSTQARAVLNSYLSAPPKPVIDSTDNSSLPEMLVSPPWRSKKKMTAPRLDLAPL
                     ELTPQIYWQPGEQERLAATESARYFSTESLAERMEQKSGRVVLQELGFGDDVWLFLNY
                     ILPGKLDAARNSLIVQWHYYQGRVEEILNGWNSPQAQLAEQALRSGHIEALINIWEND
                     NFSRYRPEKSVWNLYLLAQLPREMALTFWLRIIEKKHLFAGEDYFLSILGLDALPGLL
                     LAFSHRPKETFPLILNFGATELALPVARVWRRFAAQRDLARQWILQWPEHTASALIPL
                     VFTKPSDNSEAALLALRLLYEQGHGELLQTVANRWQRTDVWSALEQLLKQGPMDIYPA
                     RIPKAPDFWHPAMWSRPRLITNNQPVTGDALEIIGEMLRFTQGGRFYSGLEQLKTFCQ
                     PQTLAAFAWDLFTAWQQAGAPAKDNWAFLALSLFGDESTARDLTTQILAWPQEGKSAR
                     AVSGLNILTLMNNDMALIQLHHISQRAKSRPLRDNAAEFLQVVAENRGLSQEELADRL
                     VPTLGLDDPQALSFDFGPRQFTVRFDENLNPVIFDQQNVRQKSVPRLRADDDQLKAPE
                     ALARLKGLKKDATQVSKNLLPRLEAALRTTRRWSLADFHTLFVNHPFTRLVTQRLIWG
                     VYPANEPRCLLKAFRVAAEGEFCNAQDEPIDLPADALIGIAHPLEMTVEMRSEFAQLF
                     ADYEIMPPFRQLSRRTVLLTPDESTSNSLTRWEGKSATVGQLMGMRYKGWESGYEDAF
                     VYDLGEYRLVLKFSPGFNHYNVDSKALMSFRSLRVHRDNKSVTFAELDVFDLSEALSA
                     PDVIFH"
     gene            11505..11822
                     /locus_tag="RN951_003756"
     CDS             11505..11822
                     /locus_tag="RN951_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528695.1"
                     /translation="MIVQKELVAIYDYEIPVPENPFSFRLEIHKCSELFTGSVYRLER
                     FRLRPTFHQRDREDADPLINDALIYIRDECIDERKLRGESPETVIAIFNRELQNIFNQ
                     EIE"
BASE COUNT         3293 a         3166 c         3052 g         2997 t
ORIGIN      
        1 ataaatgatt tcggctttct aaatgcaatt aaaatcaggt tgccaaatta atcgtagcga
       61 tttaacacga ttcgacgttt gctatcgcta cctgcaacaa ccacttctgt cgtaacacct
      121 ttgacgggcg aagaaacctg atgacgggtg tcaacattat acgttaactg accacaatgc
      181 tgttgtggtt gactattaac catagccata ctgcatgttg ggggactgat cctgccatta
      241 atcgttaatg tggcagtctc tgaagagaat gcgggagaag ccaatccata ggcaagaaaa
      301 ataattcctg acagccaata cttattcatt gaacgttatc cctgtagtaa aggttatgcc
      361 tggatagaat gagtgcataa caaactatag ctgtacatcc actacacagc cacgaaggat
      421 gataatgaag cattgcctgt atgatcaatc gactttgtag agtttcggac gaaggtccgc
      481 agaatattcg cagtattaaa taagtgttca ttaatgcggc aaaaactaat acaccgcatc
      541 aatgtaacat ctctgcggtg tatgaagaat aaccagaatg gttaataggc gttagaccgc
      601 gcggaaggaa atctcgcctg gaatgacttc accctgccag tagagctgag ctgcaacgcg
      661 gtcagccagc tggcggtaga tagcggtaaa ttcgctctcc ggacggctga taaccgttgg
      721 cgtgccttta tcgagatcct cacgtaagga gatgtgtaac ggcatctgcc ccagcagctg
      781 tgtgtggtat ttttcagcca gtttctctgc accaccggta ccgaaaatcg gttcatggtg
      841 accacagtta ctgcaaatat gcacactcat gttctcgaca ataccaagca ccggaacctc
      901 gactttctcg aacatcacaa tgcctttttt cgcatcgatc aacgcgatgt cctgcggggt
      961 ggtgaccacg actgcaccag ttactggaat gttttgcgcc agcgtcaatt gaatgtcacc
     1021 ggtgcctggc ggcatatcaa gcaccagata gtcgagatcc ggccacaagg tttcctgcaa
     1081 catctgcatt aacgccttgc tcgccatcgg tccacgccac accatcgcat tgtcgtcagt
     1141 gaccagataa ccaattgaat tggttgccag gccatgagac ataatcggtg ccatatgggt
     1201 accgtccggc gaagttggac gctgattttc tgcgcccagc atggtgggaa ttgatgggcc
     1261 gtagatatcg gcgtccagaa tgccgacttt cgccccttcc gccgccagtg ccagcgccag
     1321 gtttaccgcc gtggaggatt tacccacgcc gcctttaccg gaactgaccg caatgatgtt
     1381 cttcacacca ttaatacccg gctgattctt cacgcgtttt aaggtggcga tattgtgcga
     1441 cagtttccag tcgatagctt tcgccccggt gatacgcagc agttcggcgc tacattgctc
     1501 ttttaactct tcaaacgcgc tatgccagac gaatggcata accagttcca catgcaacgt
     1561 gtcgtccatc caggcgacat ggtgcaacgc tttcagcgtg gtgaggttat gcttcagggt
     1621 tgggtgctga aaattggcca gtgtcccggc gaccattgcg cgcaaggctt ctggtgattt
     1681 ggcctgggat tgttcgttca tcccgactcc ttttttgtat agataaacca tcagctgata
     1741 gtttacctga agaatataga gaagtactta cttaacattt tcccatttgg tactatctaa
     1801 ccccttttca ctattaagaa gtaatgccta ctatgactca agtcgcgaag aaaattctgg
     1861 tgacgtgcgc actgccgtac gctaacggct caatccacct cggccatatg ctggagcaca
     1921 tccaggctga tgtctgggtc cgttaccagc gaatgcgcgg ccacgaggtc aacttcatct
     1981 gcgccgacga tgcccacggt acaccgatca tgctgaaagc tcagcagctt ggtatcaccc
     2041 cggagcagat gattggcgaa atgagtcagg agcatcagac tgatttcgca ggctttaaca
     2101 tcagctatga caactatcac tcgacgcaca gcgaagagaa ccgccagttg tcagaactta
     2161 tctactctcg cctgaaagag aacggtttta ttaaaaaccg caccatctct cagctgtacg
     2221 atccggaaaa aggcatgttc ctgccggacc gttttgtgaa aggcacctgc ccgaaatgta
     2281 aatccccgga tcaatacggc gataactgcg aagtctgcgg cgcgacctac agcccgactg
     2341 aattgatcga gccgaaatcg gtggtttctg gcgctacgcc ggtaatgcgt gattctgaac
     2401 acttcttctt tgatctgccc tctttcagcg aaatgttgca ggcatggacc cgcagcggtg
     2461 cgttgcagga gcaggtggca aataaaatgc aggagtggtt tgaatccggc ctgcaacagt
     2521 gggatatctc ccgcgacgcg ccatactttg gttttgaaat tccgaacgcg ccgggcaaat
     2581 atttctacgt ctggctggac gcaccgattg gctacatggg ttctttcaag aatctgtgcg
     2641 acaagcgcgg cgacagcgta agcttcgatg aatactggaa gaaagactcc accgccgagc
     2701 tgtaccactt catcggtaaa gatattgttt acttccacag cctgttctgg cctgccatgc
     2761 tggaaggcag caacttccgc aagccgacca acctgtttgt tcatggctat gtgacggtga
     2821 acggcgcaaa gatgtccaag tctcgcggca cctttattaa agccagcacc tggctgaatc
     2881 attttgacgc tgacagcctg cgttactact acactgcgaa actctcttcg cgcattgatg
     2941 atatcgatct caacctggag gatttcgttc agcgtgtgaa tgccgatatc gtgaacaaag
     3001 tggttaacct ggcctctcgt aatgcgggct ttatcaacaa gcgttttgac ggcgtgctgg
     3061 caagcgaatt ggctgacccg cagttgtaca aaaccttcac tgatgccgct gaagtgattg
     3121 gtgaagcgtg ggaaagccgc gaatttggta aagcagtgcg cgaaatcatg gcgctggctg
     3181 atctggctaa ccgctatgtc gacgagcagg ctccgtgggt ggtggcaaaa caggaaggcc
     3241 gcgatgccga cctgcaggca atttgctcaa tgggcataaa cctgttccgc gtgctgatga
     3301 cttacctgaa gccggtactg ccgaaactga ccgagcgcgc agaagcattc ctcaatacag
     3361 aactgacctg ggatggtatc cagcaaccgc tgctgggcca caaagtgaat ccgttcaaag
     3421 cgctgtataa ccgcatcgat atgaagcagg ttgaagcact ggtggaagcg tctaaagaag
     3481 aagtgaaagc agctgccgcg ccagttactg gcccactggc agatgatccg attcaggaaa
     3541 ccatcacctt tgacgacttc gcaaaagttg acctgcgcgt ggcgctgatc gaaaacgcag
     3601 agtttgttga aggttctgac aaactgctgc gcctgacact ggatctcggc ggtgaaaaac
     3661 gcaatgtctt ctccggtatt cgttctgcct acccggatcc gcaggcactg atcgggcgtc
     3721 acaccattat ggtggccaac ctggcaccgc gtaaaatgcg ctttggtatc tccgaaggca
     3781 tggtaatggc tgctggtcct ggcgggaaag atatcttcct gttaagcccg gatgctggtg
     3841 ctaaaccagg ccatcaggtg aaataatccc cctttaaggc gctgcatcga cagcgccttt
     3901 tctttataaa ttcctaaagt tgttttcttg cgattttgtc tctctctaac ccgcataaat
     3961 actggtagca tctgcattca actggataaa attacaggga tgcagaatga gacactttat
     4021 ctatcaggac gaaaaatcac ataaattctg ggcagttgag caacagggaa acgagttgca
     4081 tatcagttgg ggaaaagttg gcaccaaagg gcaaagccag ataaaaagtt tttcagatgc
     4141 tgcggcagtg gcaaaagcgg agcttaagct gattgcggag aaggtgaaga aggggtatgt
     4201 ggagcaagcg aaggataatt ctttgcaacc ttcccaaacg gtaacgggct ctctcaaggt
     4261 agcggactta tccaccatta ttcaggaaca accctctttc gtagcagaaa cccgtgcgcc
     4321 tgacaaaaat acagatgctg ttttaccgtg gctggcgaaa gatattgctg tcgtttttcc
     4381 gcccgaagtt gtacacacca cgttaagtca tcgccgcttt cccggagttc ctgttcagca
     4441 agcagacaaa ttgacccaat tacgtcgctt agcctgtagt gtgtcgcaac gggataataa
     4501 aacagccaca tttgacttca gcgcctgttc tttagaatgg caaaacaccg tcgcccaggc
     4561 gatcagtcag atcgacggcc tgaaaacaac acagctacca tcaccagtaa tggctgtact
     4621 cacggcactt gaaatgaaat gcacaagata taaagtgcgt gaggatgtta tggatcagat
     4681 cgtccaggaa ggcggtctgg aatatgctac tgatgtaata atacaccttc aacagattga
     4741 tattaaatgg gattatgcga ataatgtcat tattattctg ccgtctggca ttgcacctga
     4801 ctacttggag caatattcca gatttgaatt acgcctacgt aaacatttat cactggcgga
     4861 agagtctctc tggcaaaaat gtgcacaaaa acttattgcc gcaattccac atattccaga
     4921 atggcggcaa ccattaattg ctttgttatt acccgaaaaa ccagaaattg cacatgaaat
     4981 tgcccagcgt ctactggggc aaaaaaaatt accctcgctt gagtggttaa aaatagtggc
     5041 gactgatgag cacattcttg cctcattaga aaaatatcac gagccatatg ccatttttga
     5101 tgattactat tgtggtgcga tatggtcagc caccgtatta caggagcaag gtgttgcagc
     5161 cctgccccga tttgctccct atgccgcaag tgactactgc gccgatgtgt tgcgtcatat
     5221 caatcatccg ttcgcattaa cactgcttat acgtgtagcc gggcatacta aacgctgtca
     5281 cgatcggatg acgaaagcct gcgctgcgtt cccacatgca gcaatggcgg cactgacgga
     5341 acttcttggg caaaaagaag agaacagttg gcgcattatg ctaatgacaa tgcttatctc
     5401 acaaccagca ctggcagaac aggtcattcc ctggctctcg acacccgcag ttgccgtact
     5461 gaaatcatgc cagcaacaac tgacacagcc ctcaaaccat gccagcgccg atctactgcc
     5521 agccgtagta gtctcccctc cctggctttc gaaaaagaaa aaatcgccga ttccggtgct
     5581 ggatttagcg ccattaggca ttgagccaat ctgttatctg acagaagaaa tcagtaatca
     5641 acttttggcg aaatatatct ggtattcaaa acacatcacg gttagccatg aagaaagtac
     5701 taccaacctg ttggcaagga tgggttttca acgacggatc gctggtacat atattaaagc
     5761 tcccgaagcg gtagttgagg catggctaaa tgaagattat tcaaccttac taagtgaatt
     5821 taaggtgttt cattcaccta ccgggcatta ttggcagttg gggattttga caacattgcc
     5881 gctggagaaa gcagtaaaag catggaatgc ccttacccta tctccacata ccgataccga
     5941 atacgccatg ttacattttg gactcaaagg gttacctggg ttagtaaact cacttgcacg
     6001 ctatccacaa gaagccttgc ccatcacgaa ttacttcgca gcgagtgagc tggctcctgc
     6061 cgtcgcccgt gccttcaaca aactgaaaac gctacgcgaa aacgcccgta gctggctgtt
     6121 gaaatacccg gaacatgccc ttaccggcct gctgcctgcg gcgctcggca aagccggtga
     6181 agcacaggat aacgcccgcg ctgccttgcg tatgcttacc gaaaacggtc atcagccatt
     6241 actgcaagaa atcgcccgac gttataacca gccggaagta accgatgcgg tgaacgctct
     6301 gcttgcgctc gatcccttag ataatcaccc gacaaaaatc cccactcttc cggcctttta
     6361 tcagccatcg ctctggacgc gcccggtatt aaaagcaaat gcccaatcac tgccagatag
     6421 cgccctcctc cacctcggtg aaatgctccg cttccctcag gaagaggctc tgtatccggg
     6481 attattgcag gtgaaagacg tctgttccgc cgactcactg gcgggatttg cctgggatct
     6541 gtttaccgcc tggcagaccg ctggcgcgcc gtcgaaagag agttgggcgt tcactgcgtt
     6601 aggcgttctc ggtaacgatg acaccgcccg caaactgacg ccattaatac gcgcctggcc
     6661 tggtgaatcc cagcataaac gcgccaccgt tgggttggat attctcgctg ctatcggtag
     6721 tgatatcgcc cttatgcagc ttaacggcat cgcccagaaa ctgaaattca aagcattaca
     6781 ggagcgggca aaagaaaaaa ttgccgacat tgccgagagc cgcgaactca cggtggcgga
     6841 gcttgaagat cggttagcac cggatctcgg tctggatgat aacggttcgc tgctgctgga
     6901 ttttggccca cggcagttca ccgtcagctt tgatgaaacc ttaaaaccgt ttgtgcgtga
     6961 tgtttccggc agccgcctga aagacctgcc caaaccgaac aaaagcgatg atgaaacgcg
     7021 ggcgaacgat gcggttaacc gctacaaatt gctgaaaaaa gatgcgcgta ccatcgccac
     7081 ccagcaggta gcaaggctgg aatccgccat gtgcctgcgc cgccgctggt cgctggaaaa
     7141 cttccagctc ttcctggttg agcatccgct ggttcgtcac ttaacccgcc gtctgatttg
     7201 gggcgtttat agcgccgaaa accagctact ggcttgcttt cgcgtagcag aagataacag
     7261 ctacagcacc gctgacgatg atcttttcac cctgccggaa ggcgatatct ctatcggcac
     7321 tcctcacgtt ctggaaatat caccaacgga tgctgccgcc tttggtcagc tttttgccga
     7381 ctacgaactg ctaccaccgt tccgccagct cgaccgtaac agctacgccc tgacagaagc
     7441 cgagcgcaat gccagtgaac tgacccgctg ggcaggcaga aaatgcccga gcggtcgggt
     7501 catgggactg gcgaataaag gttgggtgcg tggtgaaccg caggatggtg gctggatcgg
     7561 ctggatgatc aaacctctgg gccgctggtc gttaatcatg gaaatcgatg aaggctttgc
     7621 agttggtatg tcgccagccg aacttagcgc cgagcaactc ttaagcaagc tgtggctatg
     7681 ggaaggcaaa gcagaaagct atggctgggg gagtaattca acacaggaag cgcagttctc
     7741 cgtactcgat gccatcaccg ccagcgagct gattaacgat attgaagccc tgtttgaata
     7801 aggaaagagc atggacaagg aattaccgtg gctggcggat aacgcccaac tggaactgaa
     7861 atataaaaaa ggcaaaacac cactcagcca tcgcaattgg ccgggcgaac cagtgcctgt
     7921 tatcactgaa agcatcattc agacactggg tgatgaattg ctacaaaaag ctgagaagaa
     7981 aaaaaacatt gtctggcgtt atgagaattt ttcactggag tggcagtccg ccattacgca
     8041 ggccatcaac ttgatcggcg aacacaaacc ctcaatcccg gcccagacaa tggcggcgct
     8101 agtctgtatc gcgcaaaatg acagccaaca gttgctcgac gaaatcgtcc aacaagaggg
     8161 gctggaatat gcgactgagg tggtgattgc acgccagttt attacacgat gttatgagag
     8221 tgatcctctg gtagtcacat tgcagtatca gaacgaggac tatggctatg gttatcgctc
     8281 agaaacctat aacgaattcg atctccgact gtgtaagcat ctctctctgg cagaggaaag
     8341 ctgctggcag cgttgcgccg acaaactcat tgccacactg ccaggaataa ccaaagttcg
     8401 ccgccctttt attgcgctga tcctccccga aaaaccagaa atcgccaatg agttggtaag
     8461 ccttgaatgc ccgcggactc attttcattc taaggagtgg ttaaaagttg ttgctaatga
     8521 ccccacagcg gtgagaaaac tcgaacgcta ctggagccag gatatattta gcgatcgaga
     8581 agccagctac atgtcgcatg aaaaccactt cggctacgcg gccagcgccg cccttttgcg
     8641 cgaacaagga ctggcagccg ttccgcgcct cgcgatatat gcccataaag aagattgcgg
     8701 cagtctgctg gtacaaatta accatccgca agtcatccgc accttgctgt tagttgctga
     8761 taaaaacaaa cccagcctgc aacgtgtggc taaatacagt aaaaacttcc cccatgcgac
     8821 actcgccgca ctggcagaac tgctggcgtt aaaagaacca ccagcccgcc caggttatcc
     8881 aatcatcgaa gacaaaaagc tgcctgcaca gcaaaaagca cgcgatgaat actggcgtac
     8941 gctgttacaa acgctgatag catcgcagcc acaactagca gaaagggtga tgccgtggtt
     9001 aagtactcaa gccagggcag tgctgaatag ttatttatcg gcaccgccaa aaccggttat
     9061 tgatagcacc gataacagca gtctgcctga aatgctcgtt tcaccaccgt ggcgtagtaa
     9121 gaaaaaaatg acagctccac gtcttgattt ggcaccgctc gaattaactc cgcaaattta
     9181 ctggcaacca ggcgaacaag agaggcttgc cgccactgag tctgcccgtt atttcagcac
     9241 ggaatctctt gcggaacgca tggaacaaaa aagtggacga gttgtattac aggaactggg
     9301 ttttggggat gatgtatggc tgtttctgaa ttatatactc cccggaaaac tggatgctgc
     9361 acgcaattca ctcattgttc agtggcatta ctaccagggg cgggttgaag agatcctgaa
     9421 tggctggaac tccccgcaag cacaattagc agaacaggcg ctccgcagcg gtcacataga
     9481 agcgttaatt aacatatggg aaaatgacaa cttctcacgt tatcgtccgg aaaagagtgt
     9541 ctggaacctg tatttattgg cacagttgcc gcgtgagatg gctttgacct tctggctgcg
     9601 tatcattgag aaaaagcatc tgttcgcggg tgaggactat tttctcagta tcctcggatt
     9661 ggatgcgcta ccaggtctgc tgttggcttt ttcacatcgt ccaaaagaaa catttccgtt
     9721 aattttaaat tttggcgcaa cagaactggc gctgcctgtt gcccgcgtct ggcgacgttt
     9781 cgcggcgcag cgtgatctgg ctcgccagtg gattttacaa tggccggaac atacggctag
     9841 tgcacttatc cctcttgtct ttaccaaacc cagcgataat agcgaagccg cattacttgc
     9901 cctgcgttta ctgtacgaac agggacatgg cgaattgcta caaaccgtgg caaaccgctg
     9961 gcagcgtaca gatgtatggt ctgccctgga gcagttgctt aaacagggtc caatggacat
    10021 ttacccggca cgcattccaa aagcccctga tttctggcat ccggcaatgt ggtccaggcc
    10081 tcgacttatc actaataatc agcctgttac cggtgacgct ctggaaatta tcggcgaaat
    10141 gctgcgcttt acccaggggg gacgttttta tagcgggctg gaacaactga aaacgttctg
    10201 ccagccacaa acgctggcag cttttgcctg ggatctcttc actgcgtggc aacaagctgg
    10261 tgcccccgca aaagacaact gggcatttct ggcgttaagt ctctttggtg acgaaagcac
    10321 ggcacgggat ctgacgacac agatcctcgc ctggccacaa gaaggcaaat ctgcccgtgc
    10381 tgtcagcggc ctgaacatcc ttaccctgat gaataatgat atggcgctga tacagctgca
    10441 tcatatatcg caacgggcta aatcccgccc cttacgtgat aacgcggcgg aatttcttca
    10501 ggtggtcgca gaaaatcgcg ggctaagcca ggaagagcta gcggacagat tagtcccaac
    10561 cctgggcctt gatgatccgc aggcgttgag ttttgatttt ggtccccggc agtttaccgt
    10621 tcgcttcgat gaaaacctca acccggttat ctttgatcag caaaacgttc gccagaaaag
    10681 cgttccccgg ttgcgcgccg atgacgatca actgaaagcg cccgaggcac tggcccgact
    10741 aaaagggcta aaaaaagatg ctactcaggt gagcaaaaac ctgctcccgc gtcttgaagc
    10801 tgccctacgt accacccgac gctggtcgct ggcagatttt catactctgt ttgttaatca
    10861 tccctttacc cgcctggtta cccagcgatt aatatggggc gtgtatccgg caaatgaacc
    10921 gcgttgttta ctcaaagcct ttcgtgtggc cgcagagggg gagttctgca atgcgcaaga
    10981 tgagccaatt gacctgcctg cggacgctct gattggcatt gcccacccgt tagaaatgac
    11041 agtagaaatg cgcagtgaat ttgcacagct ttttgccgat tacgaaatta tgccgccttt
    11101 tcgccagttg tcgcgccgca cggtgctgct cacacctgac gagtcaacca gtaacagcct
    11161 gactcgctgg gaaggtaaat ccgctaccgt tgggcagctt atgggaatgc gatacaaagg
    11221 ctgggagtca ggttatgagg acgcatttgt ctatgacctg ggtgagtacc ggctggtcct
    11281 taagttttca cccggtttta accactacaa tgttgatagc aaagcgctaa tgagcttccg
    11341 ttctcttcga gtgcaccgtg acaataaatc cgtcactttt gccgaacttg atgtgtttga
    11401 tttgagtgag gcgttaagcg cacctgacgt cattttccat taaaaacaca gcgggcagtg
    11461 atgcaactgc ccgttatcaa cacgacttac cagcggggaa agcgatgatc gtgcaaaaag
    11521 agctggttgc tatttacgat tatgagatcc ctgtacctga aaatccgttt tccttcagac
    11581 ttgagatcca taaatgctct gaattattta caggttccgt ctatcgactg gagcgattcc
    11641 ggctacgtcc aacatttcat caacgtgatc gagaagatgc tgacccgcta ataaatgatg
    11701 cgttgattta tataagagat gagtgtattg atgagcggaa attacgaggt gaatcacctg
    11761 aaactgtaat agcaattttt aatcgtgaac tacagaatat attcaaccaa gaaatagaat
    11821 aatatactct agataattaa agtcgcagca catgcaactt gaagtatgac gagtatagct
    11881 ttcttaaagg gggaaacggt attccccctt agatgcgttt caatttgccc gttacttcaa
    11941 caaatcaatc aaccgtaaca gagccactaa taactccagt acggcaatga gcacggttaa
    12001 cttttgtgtc agcgtgtcca tccgctctcc ttattaagga gcgcaacacc agcaccttac
    12061 ccttacactg cctgttgata ctggtttacg tatgttggta cgaaacgttg ctctccggat
    12121 cagggcaccg cctgcggcac cacccgtccg gcagccagga cttaaaattg gtccgatccg
    12181 gcacaacctc ccaacgggca ggattataaa tctcactcac tgaattgcaa tggagtgtgg
    12241 atatggttat aatttattcg ttggtacgaa atgttgcaca atcagcaagt tagcgtcact
    12301 gtagtaaata aaagaacctg cctcaccagc aggttttttt attttctgcg atctactttc
    12361 cagatatttt ttgccaatag cccaacataa atattcacat cccggtcaaa tggtgcgttg
    12421 aatataaaat cgatgaattt ataaataaaa atgagttata tgatgaatta ataaaaacag
    12481 taatcatttt attaaagggg gaagcggt
//
LOCUS       DAPOAV010000106        12456 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.106, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000106 DAPOAV010000000
VERSION     DAPOAV010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12456
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.106"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..1297)
                     /locus_tag="RN951_003757"
     CDS             complement(<1..1297)
                     /locus_tag="RN951_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002209167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HDX2528696.1"
                     /translation="MKSSSHFTVFEYGHLVSEEGDARINNAVVLPADLFKWLELRCLK
                     DDADNTHRLLTLSSRNGVKTLQVKNYAGVISLPGGRFLEILPKTGQDNEDTVRQQLLM
                     MLRTLKSFRHIASSESGVKISKMPLMDIFIQQFIESVRKIVQRGLKRDYLRQEDNLPW
                     MKGRLRISAQLSKNCIRRDRFQVEYDEYSVNRLENRILKTAINKISRQTSNPQLLQQI
                     TQLQFHFENITSVHDAYIAFEQLHFDRHMHHYEQALAWAKMILLGDSPHCMYGDVYAF
                     SLLFPMEAVFESFVTTWMRYRYYDKWRVDAQVSSKNLISYNGKALFKLRPDICLRPRK
                     STTGSVITCDVKWKIVNGRKDSLEQSQADLYQMLAYGLNYQEGEGDMILIYPYHNGFN
                     QPSPHPYEFSHQKENRLRLWVVPFFIGESLQTSELRFPSG"
     gene            complement(1294..3348)
                     /locus_tag="RN951_003758"
     CDS             complement(1294..3348)
                     /locus_tag="RN951_003758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HDX2528697.1"
                     /translation="MVQDSSALAPFFRAQIEKNNQYNSVWGKHYRQLVEQIQAEKPNF
                     SEATIRQVWYERDNGVSSLMQGGMSLVEFENAQKDLLTLTRQIAEECTQENYNRVIER
                     LIKLKADGVLNKVYRALCNRAFAAIYPSKISSVVNVNNFFSCYNYCNNHFQLGLSGER
                     EWLARNVDLKETLNRALGDDIDPIELNMSLWHLYAYEIQDKNAIGLVGSESALQENEQ
                     EDDVISSPLPKNTILYGPPGTGKTYRTIEIAVQICDPIAYSLQEGKDESEKRRELKKI
                     YDQLIKDNRVRFITFHQSFGYEEFIEGLRAETTDDGNVKYEIKAGIFKQICEDAAFGH
                     AGAQEMLDSALTRLQERLSEGENITLETQQGKAFQLTYKSQTNFGIFPSQSKKEDLGQ
                     GYNAYLKDIRQVYQDPRAKVHNPSYVRSILNYLINQRYLPLNTQSVASEKKENYVLII
                     DEINRGNISKIFGELITLIEPSKRAGEPESLSVLLPYSSTPFSVPNNLYLIGTMNTAD
                     HSLTALDTALRRRFDFEAMLPDITVLKDTVIKGIDLPRLLQTLNDRIQVLYDREHMLG
                     HAFFIPVVQAKEDEALAFERFKRIMRNKILPLLEEYFYNDWQKIRMVLADNQKEEAPD
                     LQFVREVKYQKKYADLFGDNGTDDLGTSFHLAAEDDNVWDNPIAWQQIYAPQKEKRRS
                     AE"
     gene            complement(3706..4539)
                     /locus_tag="RN951_003759"
     CDS             complement(3706..4539)
                     /locus_tag="RN951_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014227719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
                     /protein_id="HDX2528698.1"
                     /translation="MQTEAEVLTDHNEIICSTNIERIVTGRDSALKQIATLIQKLDDI
                     SSLTSSIGGDVAGTWGMRNGYAFDCWLMQPTDKAMPVITRNIDRSIWRDLMLKSGMLT
                     LMDAEARSQWAKNLEEGELPAISEANILSTFEQLHHNKQDVFERGIINVFKGLSWDYK
                     TNNPCYFGKKIIVNNLVKHDRWGYSLYWGWRRDQLADLERMFYLLDGKTIPDNRHDVS
                     IRFMDFVRDNPHQQIFEDELFTIRYFQKGSGHITFKRLDLVDKMNDIVAKHYPSALSA
                     K"
     gene            4845..6401
                     /locus_tag="RN951_003760"
     CDS             4845..6401
                     /locus_tag="RN951_003760"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005220915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HDX2528699.1"
                     /translation="MTSLQQRAELHRQIWQIANDVRGSVDGWDFKQYVLGALFYRFIS
                     ENFSSYIEAGDDSICYAKLDDSVITDDIKDDAIKTKGYFIYPSQLFCNVAAKANTNDR
                     LNADLNSIFVAIESSAYGYPSEADIKGLFADFDTTSNRLGNTVKDKNARLAAVLKGVE
                     GLKLGDFNEHQIDLFGDAYEFLISNYAANAGKSGGEFFTPQHVSKLIAQLAMHGQTHV
                     NKIYDPAAGSGSLLLQAKKQFDDHIIEEGFFGQEINHTTYNLARMNMFLHNINYDKFD
                     IKLGNTLTEPHFRDEKPFDAIVSNPPYSVKWIGSDDPTLINDERFAPAGVLAPKSKAD
                     FAFVLHALNYLSAKGRAAIVCFPGIFYRGGAEQKIRQYLVDNNYVETVISLAPNLFFG
                     TTIAVNILVLSKHKTDTNVQFIDASELFKKETNNNILTDAHIEQIMQVFASKEDVAHL
                     AKSVAFEAVVANDYNLSVSSYVEAKDNREIINIAELNAELKTTVSKIDQLRKDIDAIV
                     AEIEGCEVQK"
     gene            6398..7148
                     /locus_tag="RN951_003761"
                     /pseudo
     CDS             6398..7148
                     /locus_tag="RN951_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001435889.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            7166..7663
                     /locus_tag="RN951_003762"
     CDS             7166..7663
                     /locus_tag="RN951_003762"
                     /inference="COORDINATES: protein motif:HMM:NF013579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDX2528700.1"
                     /translation="MGYIDYHASQEFISEEDYAIVMRRGLPKKGDVLITTEAPCGFVA
                     QVNRENIALAQRVIKYRSKNTQLSNSFLKHYLLGSQFQDKLMQAATGSTVKGIKGSRL
                     HQLKIPIPSKVEQDRIVAILDKFDTLTNSITEGLPREIELRQKQYEYYRDLLFSFPKP
                     ETVSN"
     gene            7785..10901
                     /locus_tag="RN951_003763"
     CDS             7785..10901
                     /locus_tag="RN951_003763"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001764166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HDX2528701.1"
                     /translation="MTHQTHTIAESNNFIVLDKYIKAEQTGDSYQSESDLERELIQDL
                     QNQGYEFIAVKSQSAMLANAREQLQSLNGVVFNDSEWRRFTEQYLDNPSDGILDKTRK
                     IHIDYICDFIFDDGRLENIYLIDKKNLMRNKVQIIQQFEQAGSHANRYDVTILVNGLP
                     LVQIELKKRGVAIREAFNQIHRYSKESFNSENSLFKYLQLFVISNGTDTRYFANTTKR
                     DKNSFDFTMNWAKSDNTLIKDLKDFTATFFQKHTLLNVLVNYSVFDSSQTLLVMRPYQ
                     IAATERILWKINSSYKAKNWSNPESGGFIWHTTGSGKTLTSFKAARLATELDFIDKVF
                     FVVDRKDLDYQTMKEYQRFSPDSVNGSENTAGLKRNLDKDDNKIIVTTIQKLNNLMKA
                     ESDLPVYNQQVVFIFDECHRSQFGEAQKNLKKKFKRYYQFGFTGTPIFPENALGSETT
                     ASVFGRELHSYVITDAIRDEKVLKFKVDYNDVRPQFKSLETETDEKKLSAAENQQAFL
                     HPMRIQEITQYILNNFRQKTHRTFPGSKGFNAMLAVSSVDAAKAYYATFKRLQEEAAN
                     KSATYKPLRVATIFSFAANEEQNAIGEISDETFDTSAMDSSAKEFLDAAIREYNSYFK
                     TNFSTDSNGFQNYYRDLAQRVKNQDIDLLIVVGMFLTGFDAPTLNTLFVDKNLRFHGL
                     MQAFSRTNRIYDATKTFGNIVTFRDLERSTIDAITLFGDKNTKNVVLEKSYAEYMEGF
                     TDAATGEAKRGFMAVVSELEQRFPDPASIESEKEKKDFVKLFGEYLRAENILQNYDEF
                     ATLKALQQIDLSDPVAVEKFKAEHYVDDEKFAELQMIRLPAERKIQDYRSAYNDIRDW
                     QRREKEADKKEKSTTDWDDVVFEIDLLKSQEINLDYILGLIFEHNRQNKGKGEMTEEV
                     KRLIRSSLGNRAKEGLVVDFIQQTNLDDLPDKASIIDAFFTFAQREQQREAAALIKEE
                     NLNEEAAKRYIRTSLKREYATENGTELNETLPKLSPLNPQYKTKKQTVFQKIVAFIEK
                     FKGVGGQI"
     gene            complement(11389..11547)
                     /locus_tag="RN951_003764"
     CDS             complement(11389..11547)
                     /locus_tag="RN951_003764"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528702.1"
                     /translation="MMMSDTTLSRPEVVSGHTDVIYSTSVCHILAVRKSTLLPIDTII
                     RHQVSDIS"
     gene            complement(11647..11823)
                     /locus_tag="RN951_003765"
     CDS             complement(11647..11823)
                     /locus_tag="RN951_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF957 domain-containing protein"
                     /protein_id="HDX2528703.1"
                     /translation="MKSLTTETALDILITWLQDNIDCESGIIFDNDEDKTGSAALLRC
                     IEQAREGIRTLRQQ"
     gene            complement(11840..12331)
                     /locus_tag="RN951_003766"
     CDS             complement(11840..12331)
                     /locus_tag="RN951_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312567.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528704.1"
                     /translation="MMKLALTLEADSVNVQALNMGRIVVDIDGVNLAELINMVCDNGY
                     SLRVVDESDRTSADCTPPFVALTGIRCSTAHITETDNAWLYSLSHQTSDFGESEWIHF
                     TGTGYLLRTDAWSYPVLRLKRLGLSKTFRRLVVTLIRRYGVSLIHLDASAGYLPGLPT
                     FDW"
     gene            complement(12328..>12456)
                     /gene="cbtA"
                     /locus_tag="RN951_003767"
     CDS             complement(12328..>12456)
                     /gene="cbtA"
                     /locus_tag="RN951_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system toxin CbtA"
                     /protein_id="HDX2528705.1"
                     /translation="GASSQLINSIDILRARRATGLMTRHNYRTVNNITLGKYPEAK"
BASE COUNT         3643 a         2774 c         2650 g         3389 t
ORIGIN      
        1 ccccactagg aaaacgcaac tctgatgtct gtaaactctc gccaataaag aaaggtacaa
       61 cccataaacg taacctattt tccttctgat ggctaaattc ataaggatga ggagatggct
      121 gattaaatcc gttatgatag gggtatatca aaatcatatc accttccccc tcctggtaat
      181 tcaatccata ggcaagcatt tggtagagat cggcttgaga ttgttcaaga ctgtcctttc
      241 tgccatttac tatcttccat ttaacatcac aggtaataac tgaaccagta gtacttttac
      301 gaggccgtaa acaaatatca ggccgcagct taaataaagc tttaccgtta taactaatca
      361 aattttttga acttacctgt gcgtccactc gccatttatc ataataacga taacgcatcc
      421 atgtcgtcac aaaagattca aaaacagcct ccatcgggaa aagcagtgaa aaagcataaa
      481 catccccata catacagtgt ggagaatcgc ccaataaaat catcttcgcc cacgctaatg
      541 cttgctcata gtgatgcatg tgtctatcaa agtgtaactg ctcgaaagct atataagcat
      601 catgaactga cgtgatattt tcaaagtgaa actgcagctg tgttatctgc tgtaataatt
      661 gtggattact ggtctggcga ctaatcttat tgattgcagt tttgagtatc cggttttcca
      721 gacgattgac gctgtactcg tcatactcca cctgaaaacg atcccgccta atacagtttt
      781 tgcttaattg tgcagagatc cgtaatcttc ctttcatcca tggaagatta tcttcctgac
      841 gtaaatagtc acgttttaac cctctctgca caatcttacg cacgctctct ataaattgtt
      901 gaataaagat atccatcaga ggcattttag atattttgac gccagattca gaggaggcaa
      961 tatgacgaaa tgattttaac gtacgtaaca tcatcagtaa ttgttgacga acagtatcct
     1021 cattatcctg tcctgtttta ggcaggattt cgagaaatcg cccccctggc agtgagatta
     1081 ctcctgcata gttttttacc tgcagcgttt ttactccatt ccggctgcta agggtgagca
     1141 aacgatgagt attatcagca tcgtctttca gacagcgcag ctcaagccat ttaaataggt
     1201 ctgcaggtag cactaccgca ttatttatac gggcatcacc ttcctcactc actaaatgcc
     1261 cgtattcgaa cacagtgaaa tgactggaag atttcattcc gcactcctgc gtttttcttt
     1321 ttgaggtgca taaatttgct gccaggcgat tggattgtcc caaacgttgt catcctctgc
     1381 tgccaggtga aaactggttc ccaagtcatc tgttccgtta tcaccaaaga gatcggcata
     1441 ctttttctgg tatttcacct cacgtacaaa ttgaagatct ggtgcttcct ctttttggtt
     1501 atcagccagt accatgcgaa ttttttgcca gtcattgtaa aaatattctt ccagcaatgg
     1561 tagtatctta tttcgcataa tccgtttgaa tctttcaaat gccagagctt cgtcttcttt
     1621 tgcctgcaca acagggataa aaaaagcatg ccccagcata tgttctctat cgtataaaac
     1681 ctggatgcga tcgttaagcg tctgcaatag acgaggcaga tcaatacctt taatgacagt
     1741 atctttcaga acagtaatat ctggcagcat cgcttcaaaa tcaaatctgc gacgtagtgc
     1801 agtatcaagt gcagtaagcg aatgatcagc agtgttcatg gtaccaatta aataaaggtt
     1861 attcggtaca ctaaatggag tggaagagta tggcagcaat acgctaagcg attctggctc
     1921 accagcccgt ttagatggct caataagggt aattagttca ccaaaaattt ttgaaatatt
     1981 accccgattt atttcatcaa taatgagaac atagttttcc tttttttctg aagctacgct
     2041 ctgagtattc agaggcagat aacgttgatt aattaaatag ttaaggatac tgcgtacata
     2101 agatggatta tgtacttttg ctcgtggatc ctgataaact tgccgaatat ccttcaaata
     2161 ggcattgtaa ccctgtccta aatcctcttt tttcgattgt gacgggaaaa ttccaaagtt
     2221 ggtttgactt ttatacgtca gctggaaggc cttaccctgt tgtgtttcca gcgtgatatt
     2281 ttcaccttca gataaacgtt cttgtaggcg agtaagtgcg ctatccaaca tttcctgcgc
     2341 accagcatga ccaaaggcgg catcctcgca tatctgttta aaaatacctg cctttatttc
     2401 gtattttaca ttaccgtcat cagtagtctc agctcttaaa ccttcaataa actcttcata
     2461 accaaagctc tgatgaaagg tgataaaacg cactcgatta tctttgataa gctgatcata
     2521 aatctttttc aactcgcgac gtttttcact ctcatcctta ccctcctgca gggagtaagc
     2581 gatcggatca caaatttgta cagcaatctc aatagtacga tatgttttac ctgtacctgg
     2641 cgggccatag agaattgtgt ttttaggcaa tggcgaactt ataacatcat cttcttgctc
     2701 attttcttgt aaagcacttt cgcttccaac taaaccgata gcatttttat cctgaatttc
     2761 atacgcatag agatgccaaa gtgacatatt cagctcaata gggtcgatat catcacccag
     2821 cgcacgattt agcgtttctt taagatcaac attgcgagcc agccactccc gttctccgga
     2881 aagacctagc tggaaatggt tgttgcaata attgtagcaa ctaaaaaaat tattaacatt
     2941 cacgacactg ctaatttttg atgggtatat tgctgcaaaa gcacgattac aaagagccct
     3001 atatacctta tttaatactc cgtccgcttt aagtttgata aggcgttcaa tgacccgatt
     3061 ataattttct tgtgtacact cttctgctat ctgacgggtg agcgttagaa ggtctttttg
     3121 tgcattttca aattcaacca atgacatccc tccttgcatc aggctggaga caccattgtc
     3181 acgttcatac catacctgcc gaatcgtggc ttcagaaaag tttggttttt cggcctgaat
     3241 ctgttctaca agctggcggt agtgtttgcc ccaaactgaa ttgtattgat tatttttttc
     3301 aatttgagca cgaaagaagg gggctaatgc tgatgaatcc tgaaccatct cttaatccaa
     3361 tatgtagggg ggagggaaat tgggatagcc ttatcttatc ggattaatct caaaaatgtt
     3421 aaattttgtg ataaaaaaat aactttcatc ctgaaattac cttctgccct ggagccacca
     3481 catttatctg atgacttaac tgcaaaacgc atgatgttga tggctctcag agaaggctat
     3541 agcattcttt catacgtaaa atcgctactc gtttttcaac ctgtgtgagg tttctagttg
     3601 catatggaat caactgtttt taggtaaaca tcgtttccag taaatggata tgccgaaatt
     3661 cagagggttc cagtaacgac attattgaca gcaaacatac gacattcatt ttgctgataa
     3721 cgctgacgga tagtgcttcg ccacaatgtc attcatctta tccaccagat ccagtcgctt
     3781 gaatgtgatg tgtccactgc ctttctgaaa gtagcgaata gtgaacaact catcttcgaa
     3841 aatctgctga tgcggattat cgcgcacaaa atccataaac cggatggaga catcatgccg
     3901 gttatcggga atggtcttcc catccagcag gtagaacatc cgttccagat cggcaagctg
     3961 atctcgccgc cagccccagt acaggctgta gccccatctg tcatgcttca ccagattgtt
     4021 aacgataatc ttcttaccga aataacaggg attattggtt ttgtagtccc agctcaatcc
     4081 cttaaataca ttgataatcc cacgttcgaa aacgtcctgc ttgttatggt gcaactgctc
     4141 aaaagtactc aggatgttgg cttcgctaat cgccgggagc tcgccctcct ctaggttctt
     4201 tgcccactga ctgcgggctt cggcatccat cagagtcaac atcccggact tcagcatgag
     4261 atcgcgccag atactgcgat cgatatttcg ggtgatcacc ggcatcgctt tgtcggttgg
     4321 ctgcatcagc cagcaatcaa aggcatatcc attacgcatt ccccaggttc cagccacatc
     4381 accgccaata ctggatgtca ggctggagat atcatcaagt ttttggatta acgtcgctat
     4441 ctgcttcagt gcactatcac gtcctgtgac gatacgctca atattggtcg agcaaattat
     4501 ctcgttatga tcggttagga cttcagcttc tgtttgcata atcttttgtc cgtaaaaaaa
     4561 tacactcgcc gttagtagct gacggattat ccactagtga aagattgggt aaataatgag
     4621 attgaaaatc gggaaggtga ctcgcaataa attatctgat cacctacgga tggacgatgg
     4681 gcatataaag tagcctcctg acgcaagcgg tgatgctgaa taagatgcac taacaatctg
     4741 gtgttgaatc ccctcctcac cgtcatacaa atctgaaaaa ccaaacaact tccggtaaaa
     4801 tcccggcaaa agccgacgtt aaaaacacat tcaaaggata aaaaatgacc agtcttcagc
     4861 agcgcgcgga gcttcatcgc caaatctggc aaattgctaa cgatgtcaga ggttcggtcg
     4921 atggatggga ttttaagcaa tacgttctgg gcgcgctttt ctaccgtttt atcagcgaaa
     4981 atttttccag ctatattgaa gccggtgatg acagcatctg ttatgcgaaa ctggatgaca
     5041 gcgtaattac tgatgacatt aaagacgatg ccatcaaaac caaaggctac ttcatctacc
     5101 caagtcagct tttctgcaac gtagctgcga aagcaaatac caatgacaga ctgaacgcag
     5161 atttaaacag catcttcgtt gctatcgaaa gttctgctta cggttatcct tcagaagcag
     5221 acatcaaagg tttgtttgct gatttcgata ccaccagtaa ccgcctgggt aacaccgtta
     5281 aggataaaaa tgcccgcctg gccgcggttc tgaaaggggt tgaagggtta aagcttggcg
     5341 actttaacga acatcagatt gacctgttcg gcgatgccta tgagttcctg atttctaact
     5401 atgccgcgaa tgccggtaag tcaggcggcg agttctttac accgcagcac gtctctaagc
     5461 tgattgcaca actggctatg cacgggcaga cccacgttaa caaaatctac gacccggcag
     5521 caggttccgg ttctctgtta ttgcaggcta aaaagcagtt tgatgaccac atcatcgaag
     5581 aaggtttttt tggtcaggaa atcaaccata cgacctataa cctggcgcgt atgaacatgt
     5641 ttttgcacaa catcaactac gacaagtttg atatcaagct gggcaatacg ctgactgagc
     5701 cgcacttcag agatgaaaaa ccgtttgatg ccatcgtttc taacccgccg tattcggtga
     5761 aatggattgg cagcgatgac ccgacgctga ttaacgatga gcgttttgcc ccggctggcg
     5821 ttctggcccc caaatccaaa gctgactttg cgtttgtatt acatgcgctg aactatcttt
     5881 cggccaaagg tcgtgctgcg attgtctgct tcccgggtat tttttaccgt ggcggcgcag
     5941 agcagaaaat ccgtcagtat ctggtcgata ataactatgt cgaaaccgta atttcactgg
     6001 ctccgaacct gttctttggc accaccattg ccgtaaacat tctggttctg tccaaacata
     6061 aaacggatac caacgttcag tttattgatg ccagcgaact gttcaaaaaa gagaccaaca
     6121 acaatatcct gaccgatgcc catatcgaac agattatgca ggtatttgcc agcaaggaag
     6181 atgttgctca tctggcaaaa tctgtcgcgt tcgaagccgt tgtcgcgaat gactataacc
     6241 tgtcggtgag cagctatgtg gaagcgaaag ataaccgcga aattatcaat attgctgaac
     6301 tgaatgcaga gctgaaaacc acggtcagca aaatcgacca gttgcgtaaa gatattgatg
     6361 caattgtggc tgaaattgaa ggctgcgagg tgcagaaatg agcgagttga gttatctgga
     6421 aaaattgatg gatggggttg aggttgagtg gttgccactc tcaaaagtat tcaacttaag
     6481 gaatggttat acaccgtcta aaactaaaaa agaattttgg gcgaatggtg atataccttg
     6541 gttcagaatg gatgacatac gtgaaaatgg tagaattcta gggaattcac ttcaaaaaat
     6601 ttcatcctgc gccgtaaaag gggggaaact atttcctgaa aattcaatat taatatcaac
     6661 gtcggcaaca attggtgagc atgctttaat cactgtacct catctagcca atcaaaggtt
     6721 tacatgtttg gctttaaaag agtcttatgc tgattgcttt gatattaaat ttttatttta
     6781 ctactgtttt tctttagctg agtggtgccg aaaaaacaca acgatgtcca gttttgcgtc
     6841 tgttgatatg gatggattca aaaaattttt aatccctcgc ccctgcccgg ataatccgga
     6901 aaaatccctt gccatccagt ctgaaatcgt tcggattctg gacaaattca gcgagcttac
     6961 agcagagctt acagcagagc ttaccgctga gcttaacatg cgtaaaaaac agtacaacta
     7021 ttatcgcgac cagttgttga gttttgatga gagtagtgtt gaatggaaaa cgttacttga
     7081 ggcttgtgac tatgtagatt atcgagggaa aaccccaaaa aaaacccaga gcggaatatt
     7141 cctggtaaca gcgaaaaaca ttcggatggg atatatagat taccatgctt cgcaagaatt
     7201 tatttcagaa gaagattatg caattgtaat gagacgaggc ctccccaaaa aaggcgatgt
     7261 actaataact actgaggcac cttgtggttt cgtagctcaa gttaacagag aaaatattgc
     7321 tttagctcag cgagttataa aatatagaag caaaaataca cagctatcaa attcattttt
     7381 aaagcactat ttattgggta gtcaatttca ggataaattg atgcaagcgg cgacaggttc
     7441 aacagtcaaa ggaattaaag gcagcaggct tcatcaacta aagattccta tcccaagtaa
     7501 agttgagcaa gaccgaattg ttgccattct ggataaattc gacacactga ctaactccat
     7561 caccgaaggt cttccgcgtg aaatcgagtt gcgccagaaa caatacgagt actatcgtga
     7621 tttactgttc agtttcccga aacctgaaac tgtcagtaat taattgacca ttgctaccga
     7681 ccggaccacc ttaacacccg gtcagtatat agactatttt ttacgcgccg gaagtcactc
     7741 ttaacgccct tccggctctt gccaggcggc acaaaggatg cgctatgact catcaaacac
     7801 acaccattgc tgaatccaat aactttatcg tccttgataa gtatatcaaa gctgagcaaa
     7861 caggcgacag ctatcagagc gaatcggacc tggaacgtga actgattcag gacctacaaa
     7921 atcagggcta tgaatttata gccgtaaaat ctcagtcagc gatgctggcc aatgctcggg
     7981 aacagcttca gagcctcaat ggtgtggtgt ttaatgacag cgagtggcgg cgtttcacgg
     8041 agcagtatct ggacaacccg agcgatggca ttctggataa gacccgtaaa atccatatcg
     8101 actatatctg cgactttatt tttgacgacg ggcgtcttga gaacatctat ctgatcgata
     8161 aaaagaatct catgcgcaac aaagtgcaga ttatccagca gtttgaacag gcaggttctc
     8221 acgctaaccg ttatgacgta actatcctgg ttaatggctt gccgctggtg caaatcgaac
     8281 tgaaaaaacg cggcgtggcg attcgtgaag cgttcaacca gatacaccgt tacagcaaag
     8341 agagttttaa cagcgaaaat tctctgttta agtatctgca actgtttgtc atttccaacg
     8401 gtaccgatac ccgttatttt gccaacacaa caaagcgcga taaaaacagt tttgacttca
     8461 ccatgaactg ggcgaaatca gacaacacgc tgattaaaga cctaaaagat tttaccgcta
     8521 cctttttcca gaaacatact ctgctgaatg ttctggtgaa ctacagcgtg tttgacagta
     8581 gtcagacgct actggtgatg cgaccgtacc agattgcagc taccgaacga attttatgga
     8641 aaatcaacag ctcctataaa gcgaaaaact ggtctaaccc cgaaagcggt ggctttatct
     8701 ggcacaccac tggttccggt aaaacactga ccagctttaa agccgcgcgt ctggcaacag
     8761 aactggactt tattgataaa gtcttcttcg tggtcgacag gaaagacctc gattaccaga
     8821 ccatgaagga atatcagcgt ttttcgccag atagtgttaa cggctcggaa aatacagcag
     8881 gtcttaaacg aaatctggat aaggacgata acaaaattat cgtcaccact attcagaaac
     8941 ttaataacct gatgaaagca gaaagcgacc tgcctgtata caatcagcaa gtggtgttta
     9001 tatttgatga atgccaccgc agccagtttg gagaagcgca gaaaaacctg aagaagaaat
     9061 tcaaacgcta ttatcagttt ggttttaccg gtacccctat tttcccggaa aacgctttag
     9121 gttcagaaac aaccgccagc gtatttggtc gtgaattgca ttcgtatgta attaccgatg
     9181 cgattcgtga cgaaaaagtg ctcaaattca aggtagacta caacgatgtg cggccacagt
     9241 ttaagtcttt agagacagaa actgacgaga aaaaactgag tgcggctgaa aatcagcagg
     9301 cgtttcttca tcccatgcgt atacaggaaa ttacgcaata tattctgaat aacttccgcc
     9361 agaagaccca ccgtactttc ccaggttcca aaggctttaa tgccatgctg gcagtgagta
     9421 gcgtggatgc cgcgaaagcc tattacgcga cgtttaaacg gttacaagag gaagcagcta
     9481 ataaatcggc cacctataaa ccgctgcgtg ttgcgacaat cttctccttt gccgccaatg
     9541 aagaacaaaa tgccattggt gaaatttccg atgaaacttt tgataccagc gcaatggaca
     9601 gcagtgctaa agagtttctt gacgctgcaa ttcgtgagta taacagctat tttaaaacta
     9661 acttcagcac cgacagtaac ggttttcaga actactatcg tgatttagcc caacgggtta
     9721 aaaatcagga tatcgatctg ttaattgtcg ttgggatgtt tttaaccggc ttcgacgctc
     9781 caacattgaa cacgctattc gtcgataaaa acttgcgttt tcacggcctg atgcaggcat
     9841 tctcccgcac caaccgcatt tatgacgcta ctaaaacctt cggtaacatc gtcactttcc
     9901 gggatctgga acgctcaacc attgatgcca taacgctgtt tggtgataaa aataccaaaa
     9961 atgtggtgtt agaaaagagt tatgcagagt atatggaagg ctttacagat gctgccactg
    10021 gtgaagctaa acgcggcttt atggcagtag tttcagaact ggaacaacgg ttccctgacc
    10081 ctgccagtat tgaaagtgaa aaagagaaga aagacttcgt aaaactgttt ggtgaatacc
    10141 tgcgtgccga gaacatcctg caaaactatg atgaatttgc cacgctgaaa gccctgcaac
    10201 aaatcgatct tagcgatcct gttgcggtag aaaaattcaa agcagaacat tatgtggatg
    10261 atgaaaagtt cgctgaattg caaatgattc gtctccctgc tgaacgcaag attcaggatt
    10321 atcgttctgc ctataacgat attcgtgact ggcagcgccg tgagaaagaa gctgacaaaa
    10381 aagaaaaatc aaccactgac tgggatgacg tggtttttga aatcgatttg ctgaagtctc
    10441 aggaaataaa cctggattat atccttggac tgattttcga acacaacaga caaaacaaag
    10501 gtaagggcga aatgaccgaa gaggtcaaac gcttaattcg ttcaagcctt gggaaccgtg
    10561 ctaaagaagg attggtggtc gattttattc agcaaacgaa cctggatgat ttgccggata
    10621 aagccagcat cattgacgcg ttttttacct ttgctcaacg cgaacagcaa cgtgaagcag
    10681 cagcattgat caaagaagaa aatctcaatg aagaggcggc gaaacgctat attcgcacgt
    10741 ctttaaaacg cgaatacgca accgaaaatg gcacggaatt aaacgagaca ttgccaaaac
    10801 tcagtccgtt aaatccgcaa tataagacga aaaaacagac ggttttccag aagatcgtcg
    10861 cgtttattga gaagtttaaa ggtgtaggcg ggcagatata atgtattaat ccgaacctga
    10921 tctggcagat agctgtcaga tcaggactga gctaatacaa attaatatcg aaccgaaaat
    10981 accaacgcct gtaccaacat ttttcgtttg cgatgggttg aaattggttg gctctgagag
    11041 agttaaaata gcgagaaaga taggtaacta atggatccca gacgcaaaaa aagccgccct
    11101 tgagcgactc gatttgcata cgatgtggtg cgaaggccgg actcaaacat gcgatttaac
    11161 ctcatgattt aaaattgtta ataataaaca acaccatcct ataccaacac agataccaac
    11221 acgaaaaatc actggttttc ggcatcgaac caggacaatc aggtcctgat tgagataccg
    11281 agctctgtta ctcgtcatct tcctcgacag gctccattgc atcaagtggt actcgcacca
    11341 tcgcgataga accaatccgg ataaaagcat cttccccatc tatatcggtt aactgatatc
    11401 gcttacttga tgccggataa ttgtgtcgat tggcaacagt gtactctttc gtacagccag
    11461 aatgtggcag actgaggtgg aatagataac gtccgtatgc ccgctgacca cctccgggcg
    11521 ggagagtgtg gtatctgaca tcatcatttt tcctttctgt ttataaatga aaacgccagc
    11581 cgtgttcagg ctgacgtcag ggaagtgaaa tcgggtgagt gatcttcact ggttctggtg
    11641 caaaagttac tgttggcgca gggtacggat accctccctg gcctgttcga tacagcgcaa
    11701 cagtgctgcc gaacctgttt tatcctcatc gttgtcgaag ataattcccg attcgcagtc
    11761 gatattgtcc tgcagccacg taatcagaat atccagcgct gtttccgtgg ttaatgattt
    11821 catgttgtga atttccggat taccagtcga aagtgggtaa acccggcaga tatccggcac
    11881 tggcatccag atgaatgaga ctgacaccat aacgccggat gagtgtgacg accagacgac
    11941 ggaacgtttt tgacagcccc aggcgcttaa gccgcagaac cgggtatgac cacgcatcgg
    12001 tacgtaacag ataaccggta ccggtaaaat gaatccattc tgattcaccg aagtcactgg
    12061 tctggtgtga cagcgagtac agccaggcgt tgtccgtttc cgtgatatgt gcggtactgc
    12121 agcgtatgcc ggtaagggca acaaatggtg gcgtgcagtc tgctgaggtc cggtcagatt
    12181 catcaacaac acgaagggag tagccgttat cgcagaccat gttaatcagt tcagcgagat
    12241 taacaccatc aatgtcaacg acaattcgcc ccatattcag tgcctgtacg ttaacactgt
    12301 cggcttccag tgtcagggcc agtttcatca tttcgcctcc ggatacttac ccagggtgat
    12361 attgttcacc gttctgtagt tgtggcgggt catcagtcct gttgcccggc gagcccggag
    12421 aatatcaatg ctgttgatta actgcgacga ggctcc
//
LOCUS       DAPOAV010000107        12343 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.107, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000107 DAPOAV010000000
VERSION     DAPOAV010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12343
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.107"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(242..889)
                     /gene="ychE"
                     /locus_tag="RN951_003768"
     CDS             complement(242..889)
                     /gene="ychE"
                     /locus_tag="RN951_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter YchE"
                     /protein_id="HDX2528706.1"
                     /translation="MIQTFFDFPVYFKFFIGLFALVNPVGIIPVFISMTSYQTAAARN
                     KTNLTANLSVAIILWISLFLGDTILQLFGISIDSFRIAGGILVVTIAMSMISGKLGED
                     KQNKQEKSETAVRESIGVVPLALPLMAGPGAISSTIVWGTRYHSISYLFGFFVAIALF
                     ALCCWGLFRMAPWLVRVLRQTGINVITRIMGLLLMALGIEFIVTGIKGIFPGLLN"
     gene            1366..4041
                     /gene="adhE"
                     /locus_tag="RN951_003769"
                     /gene_synonym="adhC"
     CDS             1366..4041
                     /gene="adhE"
                     /locus_tag="RN951_003769"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDX2528707.1"
                     /translation="MAVTNVAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAAD
                     ARIPLAKMAVAESGMGIVEDKVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAE
                     PIGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKDATNKAADIVLQAAIAA
                     GAPKDLIGWIDQPSVELSNALMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTP
                     VVIDETADIKRAVASVLMSKTFDNGVICASEQSVVVVDSVYDAVRERFATHGGYLLQG
                     KELKAVQDVILKNGALNAAIVGQPAYKIAELAGFSVPENTKILIGEVTVVDESEPFAH
                     EKLSPTLAMYRAKDFEDAVEKAEKLVAMGGIGHTSCLYTDQDNQPARVSYFGQKMKTA
                     RILINTPASQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAEN
                     MLWHKLPKSIYFRRGSLPIALDEVITDGHKRALIVTDRFLFNNGYADQITSVLKAAGV
                     ETEVFFEVEADPTLSIVRKGAELANSFKPDVIIALGGGSPMDAAKIMWVMYEHPETHF
                     EELALRFMDIRKRIYKFPKMGVKAKMIAVTTTSGTGSEVTPFAVVTDDATGQKYPLAD
                     YALTPDMAIVDANLVMDMPKSLCAFGGLDAVTHAMEAYVSVLASEFSDGQALQALKLL
                     KEYLPASYHEGSKNPVARERVHSAATIAGIAFANAFLGVCHSMAHKLGSQFHIPHGLA
                     NALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKL
                     LAWLETLKAELGIPKSIREAGVQEADFLANVDKLSEDAFDDQCTGANPRYPLISELKQ
                     ILLDTYYGRDYVEGETAAKKEAAPAKAEKKAKKSA"
     gene            4165..5061
                     /locus_tag="RN951_003770"
                     /pseudo
     CDS             4165..5061
                     /locus_tag="RN951_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904641.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            complement(5343..5960)
                     /gene="tdk"
                     /locus_tag="RN951_003771"
     CDS             complement(5343..5960)
                     /gene="tdk"
                     /locus_tag="RN951_003771"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HDX2528708.1"
                     /translation="MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRF
                     GAGKVSSRIGLSSPAKLFNQNSSLFDEIRAEHEQQAIHCVLVDECQFLTRQQVYELSE
                     VVDQLDIPVLCYGLRTDFRGELFIGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQA
                     GRPYNEGEQVVIGGNERYVSVCRKHYKEALQVDSLTAIQERHRHD"
     gene            6565..6978
                     /gene="hns"
                     /locus_tag="RN951_003772"
     CDS             6565..6978
                     /gene="hns"
                     /locus_tag="RN951_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator H-NS"
                     /protein_id="HDX2528709.1"
                     /translation="MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEE
                     SAAAAEVEERTRKLQQYREMLIADGIDPNELLNSLAAVKSGTKAKRAQRPAKYSYVDE
                     NGETKTWTGQGRTPAVIKKAMDEQGKSLDDFLIKQ"
     gene            complement(7122..8030)
                     /gene="galU"
                     /locus_tag="RN951_003773"
     CDS             complement(7122..8030)
                     /gene="galU"
                     /locus_tag="RN951_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDX2528710.1"
                     /translation="MAAINTKVKKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQY
                     VVNECIAAGITEIVLVTHSSKNSIENHFDTSFELEAMLEKRVKRQLLDEVQSICPPHV
                     TIMQVRQGLAKGLGHAVLCAHPVVGDEPVAVILPDVILDEYESDLSQDNLAEMIRRFD
                     ETGHSQIMVEPVADVTAYGVVDCKGVELAPGESVPMVGVVEKPKADVAPSNLAIVGRY
                     VLSADIWPLLAKTPPGAGDEIQLTDAIDMLIEKETVEAYHMKGKSHDCGNKLGYMQAF
                     VEYGIRHNTLGTEFKAWLEEEMGIKK"
     gene            complement(8232..9245)
                     /gene="rssB"
                     /locus_tag="RN951_003774"
     CDS             complement(8232..9245)
                     /gene="rssB"
                     /locus_tag="RN951_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RssB"
                     /protein_id="HDX2528711.1"
                     /translation="MTQPLVGKQILIVEDEQVFRSLLDSWFSSLGATTVLAADGVDAL
                     ELLGGFTPDLMICDIAMPRMNGLKLLEHIRNRGDQTPVLVISATENMADIAKALRLGV
                     EDVLLKPVKDLNRLREMVFACLYPSMFNSRVEEEERLFRDWDAMVDNPAAAAKLLQEL
                     QPPVQQVISHCRVNYRQLVAADKPGLVLDIAALSENDLAFYCLDVTRAGHNGVLAALL
                     LRALFNGLLQEQLAHQNQRLPELGALLKQVNHLLRQANLPGQFPLLVGYYHRELKNLI
                     LVSAGLNATLNTGEHQVQISNGVPLGTLGNAYLNQLSQRCDAWQCQIWGTGGRLRLML
                     SAE"
     gene            complement(9337..10242)
                     /gene="rssA"
                     /locus_tag="RN951_003775"
     CDS             complement(9337..10242)
                     /gene="rssA"
                     /locus_tag="RN951_003775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase RssA"
                     /protein_id="HDX2528712.1"
                     /translation="MRKIKIGLALGSGAARGWSHIGVINALKKVGIEIDIVAGCSIGS
                     LVGAAYACDRLSALEDWVTSFSYWDVLRLMDLSWQRGGLLRGERVFNQYREIMPETEI
                     ENCSRRFAAVATNLSTGRELWFTEGDLHLAIRASCSIPGLMAPVAHNGYWLVDGAVVN
                     PIPISLTRALGADIVIAVDLQHDAHLMQQDLLSFNVSEENSENGDSLPWHARLKERLG
                     SITTRRAVTAPTATEIMTTSIQVLENRLKRNRMAGDPPDILIQPVCPQISTLDFHRAH
                     AAIAAGQLAVERKMDELLPLVRTNI"
     gene            10355..10813
                     /locus_tag="RN951_003776"
     CDS             10355..10813
                     /locus_tag="RN951_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YchJ family protein"
                     /protein_id="HDX2528713.1"
                     /translation="MSQLCPCGSAVEYSLCCHPYVSGEKVAPDPEHLMRSRYCAFVMQ
                     DADYLIKTWHPSCGAAALRAELMAGFAHTEWLGLTVFEHCWQDADNIGFVSFVARFTE
                     GGKTGAIIERSRFLKENGQWYYIDGTRPQFGRNDPCPCGSGKKFKKCCGQ"
     gene            10863..11705
                     /gene="purU"
                     /locus_tag="RN951_003777"
     CDS             10863..11705
                     /gene="purU"
                     /locus_tag="RN951_003777"
                     /EC_number="3.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formyltetrahydrofolate deformylase"
                     /protein_id="HDX2528714.1"
                     /translation="MHSLQRKVLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHR
                     TGRFFMRTELEGIFNDSTLLADLDSALPEGSVRELNPAGRRRIVILVTKEAHCLGDLL
                     MKANYGGLDVEIAAVIGNHDTLRSLVERFDIPFELVSHEGLTRNEHDQKMADAIDAYQ
                     PDYVVLAKYMRVLTPEFVARFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAH
                     YVNDNLDEGPIIMQDVIHVDHTYTAEDMMRAGRDVEKNVLSRALYKVLAQRVFVYGNR
                     TIIL"
     gene            11865..11949
                     /locus_tag="RN951_003778"
     tRNA            11865..11949
                     /locus_tag="RN951_003778"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11899..11901,aa:Tyr,seq:gta)
     gene            11993..12124
                     /locus_tag="RN951_003779"
     ncRNA           11993..12124
                     /ncRNA_class="other"
                     /locus_tag="RN951_003779"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
     gene            12159..12243
                     /locus_tag="RN951_003780"
     tRNA            12159..12243
                     /locus_tag="RN951_003780"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12193..12195,aa:Tyr,seq:gta)
BASE COUNT         3345 a         3074 c         2806 g         3118 t
ORIGIN      
        1 tctaccaaag gcagtggaat tactaatatc atttcaatta ttcttcagca agcccaggat
       61 tatgatgtgg cgaaaataac atgatggtga ggagaagcag ttaaggaaat ccttataact
      121 aactgtaatt tgagaagaat atttttacct attccttttg cttttgataa ctgcgcggga
      181 acaaagtaaa aataatgacg aagtaaacgg agcatggcag ctccgtttca tttgaaagga
      241 attaattaag caggccgggg aaaatcccct taataccagt aacgataaat tcaatcccca
      301 atgccatcag caatagcccc ataatacgcg taatcacgtt gatgccggtc tggcgtaaaa
      361 cccgtaccag ccacggtgcc atgcggaaca atccccaaca acataaagcg aacaatgcaa
      421 tagccacaaa gaaaccaaac agatagctaa tgctgtgata acgcgtaccc cagacgatgg
      481 tagaactgat cgcccctggc cccgccatca acggcaacgc cagtggcacc acaccaatgc
      541 tttcacgtac cgcggtttct gatttttctt gcttgttctg tttatcctcg ccaagcttgc
      601 cgctgatcat cgacatcgct attgtcacca ccaggatacc cccggcgata cggaacgaat
      661 caattgatat accaaaaagt tgtagaatcg tgtcgccgag aaaaagcgag atccacaaga
      721 taatggccac agacaggttg gctgtaaggt tagttttgtt tcgcgctgcc gctgtctgat
      781 aactggtcat gctgataaag acgggaataa tccctaccgg gttgaccagc gcaaataacc
      841 cgatgaaaaa tttgaagtaa acgggaaaat caaaaaaggt ctgaatcacg gttagctccg
      901 aagcaaaagc cggataatgt tagccataaa taaggttgaa aagacgcgct gacaatacgc
      961 cttttgacag catttttcac ctcctaacta cttaaaattg ctatcattcg ttattgttat
     1021 ctagttgtgc aaaacatgct aatgtagcca ccaaatcata ctacaattta ttaactgtta
     1081 gctataatgg cgaaaagcga tgctgaaagg tgtcagcttt gcaaaaattt gatttggatc
     1141 acgtaatcag tacccagaag tgagtaatct tgcttacgcc acctggaagt gacgcattag
     1201 agataataac tctaatgttt aaactctttt agtaaatcac agtgagtgtg agcgcgagta
     1261 agcttttgat tttcataggt taagcaaatc atcaccgcac tgactatact ctcgtattcg
     1321 agcagatgat ttactaaaaa agtttaacat tatcaggaga gcattatggc tgttactaat
     1381 gtcgctgaac ttaacgcact cgtagagcgt gtaaaaaaag cccagcgtga atatgccagt
     1441 ttcactcaag agcaagtaga caaaatcttc cgcgccgccg ctctggctgc tgcagatgct
     1501 cgaatcccac tcgcgaaaat ggccgttgcc gaatccggca tgggtatcgt cgaagataaa
     1561 gtgatcaaaa accactttgc ttctgaatat atctacaacg cctataaaga tgaaaaaacc
     1621 tgtggtgttc tgtctgaaga cgacactttt ggtaccatca ctatcgctga accaatcggt
     1681 attatttgcg gtatcgttcc gaccactaac ccgacttcaa ctgctatctt caaatcgctg
     1741 atcagtctga agacccgtaa cgccattatc ttctccccgc acccgcgtgc aaaagatgcc
     1801 accaacaaag cggctgatat cgttctgcag gctgctatcg ctgccggtgc tccgaaagat
     1861 ctgatcggct ggatcgatca accttctgtt gaactgtcta acgcactgat gcaccaccca
     1921 gacatcaacc tgatcctcgc gactggtggt ccgggcatgg ttaaagccgc atacagctcc
     1981 ggtaaaccag ctatcggtgt aggcgcgggc aacactccag ttgttatcga tgaaactgct
     2041 gatatcaaac gtgcagttgc atctgtactg atgtccaaaa ccttcgacaa cggcgtaatc
     2101 tgtgcttctg aacagtctgt tgttgttgtt gactctgttt atgacgctgt acgtgaacgt
     2161 tttgcaaccc acggcggcta tctgttgcag ggtaaagagc tgaaagctgt tcaggatgtt
     2221 atcctgaaaa acggtgcgct gaacgcggct atcgttggtc agccagccta taaaattgct
     2281 gaactggcag gcttctctgt accagaaaac accaagattc tgatcggtga agtgaccgtt
     2341 gttgatgaaa gcgaaccgtt cgcacatgaa aaactgtccc cgactctggc aatgtaccgc
     2401 gctaaagatt tcgaagacgc ggtagaaaaa gcagagaaac tggttgctat gggcggtatc
     2461 ggtcatacct cttgcctgta cactgaccag gataaccaac cggctcgcgt ttcttacttc
     2521 ggtcagaaaa tgaaaacggc gcgtatcctg attaacaccc cagcgtctca gggtggtatc
     2581 ggtgacctgt ataacttcaa actcgcacct tccctgactc tgggttgtgg ttcttggggt
     2641 ggtaactcca tctctgaaaa cgttggtccg aaacacctga tcaacaagaa aaccgttgct
     2701 aagcgagctg aaaacatgtt gtggcacaaa cttccgaaat ctatctactt ccgccgtggc
     2761 tccctgccaa tcgcgctgga tgaagtgatt actgatggcc acaaacgtgc gctcatcgtg
     2821 actgaccgct tcctgttcaa caatggttat gctgatcaga tcacttccgt actgaaagca
     2881 gcaggcgttg aaactgaagt cttcttcgaa gtagaagcgg acccgaccct gagcatcgtt
     2941 cgtaaaggtg cagaactggc aaactccttc aaaccagacg tgattatcgc gctgggtggt
     3001 ggttccccga tggacgccgc gaagatcatg tgggttatgt acgaacatcc ggaaactcac
     3061 ttcgaagagc tggcgctgcg ctttatggat atccgtaaac gtatctacaa gttcccgaaa
     3121 atgggcgtga aagcgaaaat gatcgctgtc accaccactt ctggtacagg ttctgaagtc
     3181 actccgtttg cggttgtaac tgacgacgct actggtcaga aatatccgct ggcagactat
     3241 gcgctgactc cggatatggc gattgtcgac gccaacctgg ttatggacat gccgaagtcc
     3301 ctgtgtgctt tcggtggtct ggacgcagta actcacgcca tggaagctta tgtttctgta
     3361 ctggcatctg agttctctga tggtcaggct ctgcaggcac tgaaactgct gaaagaatat
     3421 ctgccagcgt cctaccacga agggtctaaa aatccggtag cgcgtgaacg tgttcacagt
     3481 gcagcgacta tcgcgggtat cgcgtttgcg aacgccttcc tgggtgtatg tcactcaatg
     3541 gcgcacaaac tgggttccca gttccatatt ccgcacggtc tggcaaacgc cctgctgatt
     3601 tgtaacgtta ttcgctacaa tgcgaacgac aacccgacca agcagactgc attcagccag
     3661 tatgaccgtc cgcaggctcg ccgtcgttat gctgaaattg ccgaccactt gggtctgagc
     3721 gcaccgggcg accgtactgc tgctaagatc gagaaactgc tggcatggct ggaaacgctg
     3781 aaagctgaac tgggtattcc gaaatctatc cgtgaagctg gcgttcagga agcagacttc
     3841 ctggcgaacg tggataaact gtctgaagat gcattcgatg accagtgcac cggcgctaac
     3901 ccgcgttacc cgctgatctc cgagctgaaa cagattctgc tggataccta ctacggtcgt
     3961 gattatgtag aaggtgaaac tgcagcgaag aaagaagctg ctccggctaa agctgagaaa
     4021 aaagcgaaaa aatccgctta atcagtagcg ctgtctggca acataaacgg ccccttctgg
     4081 gcaatgccga tcagttaagg attagttgac cgatccttaa actgaggcac tataacggct
     4141 tccacaacag ggagccgttt tcttatgcca cttctcaatg atctgctcga tttcagtgac
     4201 catccgctta tgcctccgcc ctctgcacaa ctatttgcag aacaccttcc caccgagtgg
     4261 atacaacact gcctgacgct ttctgctcat gcgaccgttc gccgccgtcg tttaccgggg
     4321 gacatggtta tctggatggt ggtgcaatga gccaattacc gatgttgttc gccgtctgaa
     4381 cctgagcgcg gatggcgaag cggggatgaa cctgctggcc cgcagcgctg tcacccaggc
     4441 gcgtcagcgc gtgggggccg ccccagtgga atggctcttc cgccagaccg cacagacagg
     4501 ggcgcggaac gttacctgaa ggatgactgg cacggcctgc aactttttgc cattgatggc
     4561 gcacagttca ggacacctga taaacccgag ctgcgtgaat attatgggtc tgccaacaca
     4621 tccactaagc ggcagaacgc ctacccggtt atgcgtctgg tggccttaat gaacctggga
     4681 agtcacattc tgctgaatgc cgtgaccgca ccttaccggc agagcgaaac tgtgctggcc
     4741 cactccatgc tcgccaccat cccggataac tctattacgt tgtttgataa acttttttac
     4801 agcgaagacc tgctgctgac gctgaaccag aagggttgta accgccactg gctactgcct
     4861 gcgtggaaga atatcgcatc agaaatgata gagctgggaa acacggcgtc accagggacc
     4921 atcccgaaac gactggagca tcttcggggt gctctggaag tggtgttcat aacaaaacgc
     4981 ccccgaccat caaggccgag gtcggttaag atatcaaaaa cccgttatcc tgtgaaacat
     5041 agtgccgctc ctcttaagtg aacggcattg cccttctggg gccgtatttt ttgtttaccc
     5101 aaagcaactt ttccataaac cgacagcatt agccttcatc atatttgcga cgatgtataa
     5161 cgcctaaaca cagggatatt gtactttaca ggtcacaagt caacgtcggt gcttaagagc
     5221 cctgtgaggc gtatagcggc gttaaaaaac tgccgagaag ggtatatagc ccggaagaag
     5281 tgcgtaaaac gaactgacag gataaaagtg ccctgctcac cctgtcagta aagaaattct
     5341 tattaatcgt ggcgatgcct ttcctgaata gccgttaatg agtcgacttg taacgcctct
     5401 ttatagtgtt tacggcatac agaaacgtat cgttcattac caccaattac cacctgctca
     5461 ccttcgttat aaggtctgcc tgcttgatca agacgcagca ccatgcttgc tttacggcca
     5521 caaaaacaga tggtttttaa ttcaaccagt ttgtcggacc atgccagtaa gtattggctg
     5581 ccaataaata attcacctcg aaaatcggta cgtaaaccat aacaaagtac gggtatatcg
     5641 agttgatcga caacctccga taattcatat acttgttgtc tggttaaaaa ctggcattca
     5701 tcaaccagta cgcaatgaat tgcctgctgt tcatgttccg cacgaatctc atcaaataat
     5761 gatgaatttt ggttaaataa ttttgcaggc gatgacaaac ctatacgcga actgactttc
     5821 ccggcaccaa agcgatcatc aatttctgcc gtatatacga cagtgcgcat gccgcgttcc
     5881 tggtaattgt atgaagattg caacaatgct gtagacttac ccgcattcat tgcggaatag
     5941 tagaaatata gctgtgccat cagccacagg ccctcaatga tatgaaataa agttggctgg
     6001 agtttatcat aattcgtcag tttttcagct caacagtatg cacagaagtg ggtatatgcg
     6061 ttctccctta cgaagccttg cataaccctt ctgagctatc attacaactg cctcgcttgt
     6121 tataagcggg taaatgactg ctggtaacta ttcacaatct ttaacctgtt gcgcaagtaa
     6181 tagccctctg ttgacctcca ggagatagtg caatactaag tccatgctct tattgcgact
     6241 gttctacttt tcatcattcg cttaataggg aattctcgta aacacaacta atacagaaga
     6301 ctgaaaggtc gtcagcctac gataatctcc ccataaaatg tgacatgaat caggaagttt
     6361 taacctcacg tgctgcgaaa tcatcggtgt aaatagggct atatgccgcg tcttttctgg
     6421 ctaattttat gaaaagatat ttattggcgg cacaaaataa agaacaattt tgaattcctt
     6481 acattcctgg ctattgcaca actgaattta aggctctatt attacctcaa caaaccaccc
     6541 caatataagt ttgagattac tacaatgagc gaagcactta aaattctgaa caacatccgt
     6601 actcttcgtg cgcaggcaag agaatgtaca cttgaaacgc tggaagaaat gctggaaaaa
     6661 ttagaagttg ttgttaacga acgtcgcgaa gaagaaagcg cggctgctgc tgaagttgaa
     6721 gagcgcactc gtaaactgca gcaatatcgc gaaatgctga tcgctgacgg tattgacccg
     6781 aacgaactgc tgaatagcct tgctgccgtt aaatctggca ccaaagctaa acgtgctcag
     6841 cgtccggcaa aatatagcta cgttgacgaa aacggcgaaa ctaaaacctg gactggccaa
     6901 ggccgtactc cagctgtaat caaaaaagca atggatgagc aaggtaaatc cctcgacgat
     6961 ttcctgatca agcaataatc ttttgtagat tgcacttgct taaaatcccg ccagcggcgg
     7021 gattttttat tgtccggttt aagacaattt aataagaata agctataaaa aaacggcgtc
     7081 gattgctcaa cgccgtttcg tggataacac cgatacggat gttacttctt aatgcccatc
     7141 tcttcttcaa gccaggcttt aaattccgtg ccaagggtgt tatgacgaat accgtattca
     7201 acgaaggcct gcatgtaacc taatttatta ccgcagtcat ggctcttccc tttcatatga
     7261 taggcttcca ccgtttcttt ttcgatcagc atatcaattg cgtcggtgag ctgaatttca
     7321 tcaccagctc ccggaggggt ttttgccagc aacggccaaa tatccgcgct aagtacgtaa
     7381 cgacccacaa tagcgagatt agacggcgca acatccgctt tcggtttttc taccacacca
     7441 accatcggta cgctttcacc cggcgctaat tcaacgcctt tgcaatccac aacgccatat
     7501 gcggtcacat cagcaaccgg ttcaaccatg atctggctat gacccgtttc atcaaagcgg
     7561 cggatcatct ctgccaggtt atcctgtgac aaatcggatt catattcatc cagaataaca
     7621 tcaggcaaaa taacagctac cggttcatca cccactaccg ggtgagcaca caataccgcg
     7681 tgtcccaggc ctttcgccag accctgacga acttgcataa tagtcacgtg cggtggacaa
     7741 atagactgca cttcatcaag cagttgacgt tttacacgtt tttccagcat tgcttccagt
     7801 tcaaaactgg tatcaaagtg gttttcaata gagtttttag atgagtgtgt aaccagcaca
     7861 atttcagtaa tgccagccgc aatacattca ttcacgacgt attgaattaa tggcttatcg
     7921 acaagtggca gcatctcttt cgggatggct ttcgtcgccg gcaacatcct ggttcctaat
     7981 cccgcaacgg ggataacggc ttttttgact ttcgtattaa tggcagccat ttaaattctc
     8041 ctggactgtt cgtgttttga acgtgttcat atttctgtat cgcatcccag tatatcagca
     8101 ccccgaaggg gctaagttct gaaaaggagg cgagttagca taattaagac aattacttat
     8161 acgaatggcg acgatagtac caccagccga cattagcagg taatgcaaat ttagcccgcg
     8221 ttatcgtttg ctcattctgc agacaacatc aagcgcagtc gaccaccggt tccccatatt
     8281 tggcattgcc aggcatcgca tcgctggctc aattgattca aataagcgtt acctaaagtg
     8341 cctaacggaa caccattact gatttgcacc tggtgttcgc cggtatttaa cgtcgcattc
     8401 agacccgcag aaaccagaat gagatttttc agttcgcgat gataatagcc aactaatagc
     8461 ggaaactgcc ccggcagatt ggcctgacga agtaaatggt ttacctgctt caataacgcg
     8521 cccaactctg gcaaccgttg attttggtgt gcaagctgtt cctgtaataa tccgttaaac
     8581 aatgcgcgta ataacaaggc agcaagtacg ccattatgtc cagctcgggt gacatcaagg
     8641 caataaaatg ccagatcgtt ttccgaaagt gcggcaatat caagcaccag gccgggtttg
     8701 tccgcggcaa ccaattgacg ataattaacc cggcaatggg aaatcacctg ctgaaccggc
     8761 ggttgtagtt cctgtaataa tttcgccgct gcggcagggt tatcaaccat tgcatcccag
     8821 tcgcgaaaaa gcctttcctc ttcctcaacg cgcgaattaa acatgctggg atagagacag
     8881 gcaaaaacca tctcgcgcaa gcgattcaga tctttaactg gtttcagcaa aacatcttca
     8941 acgcccagac gtaacgcttt ggcaatatct gccatatttt cagtggcaga tatcaccaga
     9001 actggggtct ggtcgcctct gttacgtata tgctccagca gtttaagccc gttcattcgt
     9061 ggcatcgcga tatcacatat catcaggtct ggagtgaaac ctcccagcaa ctcaagggca
     9121 tccaccccat cagccgccag taccgttgtc gctcccaatg aggaaaacca tgaatccaga
     9181 agcgagcgaa atacctgctc atcttcaaca atgagaatct gttttccgac caatggctgc
     9241 gtcatgttct ctcccctgac tggctttact caatagtggc atgctattgc cacctgcgcc
     9301 tgtcagaatt aacttaagtg tagataaaaa ttctggtcaa atgttggtgc gtaccaacgg
     9361 caaaagttcg tccattttcc tttccactgc cagctgtccg gccgcaatgg cagcgtgcgc
     9421 gcgatggaaa tcaagcgtag atatttgcgg gcaaacaggt tgaatcagaa tatcgggcgg
     9481 atcacctgcc atgcggttcc ttttaaggcg gttctccagc acctggatag aagtggtcat
     9541 aatctctgtt gccgttggcg ctgtcaccgc ccgacgtgtc gttatgctgc ctaacctttc
     9601 tttcagacgc gcatgccacg gcagagaatc accattctcg ctattttctt cactgacatt
     9661 aaaggagagc aaatcttgtt gcatcaaatg agcatcgtgc tgcaggtcaa ccgctatcac
     9721 aatatcagcc cccaatgcac gcgtgaggga aataggaatt gggttaacga ctgctccatc
     9781 aaccagccag tagccgttat gtgcaacagg tgccatgagt cctggaatac tgcatgatgc
     9841 gcgaatagca agatggagat cgccttcagt aaaccataat tcacgtcccg tacttaaatt
     9901 ggtggcaaca gccgcaaagc gacgggaaca attttcgatc tctgtttccg gcattatttc
     9961 gcggtattga ttgaagacac gctcgccgcg cagtaaccca ccgcgctgcc aggagagatc
    10021 catcaggcgt aaaacatccc aataactgaa agaggtcacc caatcttcca gcgcagataa
    10081 tcgatcgcat gcataggcag cgcccaccag cgaaccaatt gaacatcctg caacgatatc
    10141 aatttcaata cccacttttt ttagcgcatt aataacgcca atatgcgacc aacctctcgc
    10201 cgcgccagat cccagcgcca gccctatttt tatctttctc attattcccg caagattccc
    10261 ctggaatgca atcgtagcca catcgctact tctcggttaa catagtgcta ctcaggcggt
    10321 taatacgccg ttattgtttc cagggagatt atttgtgtct cagctttgtc cctgtggtag
    10381 tgctgtcgag tatagcctat gttgccaccc ttatgtgtct ggtgaaaagg ttgcacctga
    10441 tccagaacat ctcatgcgtt cgcgttactg cgcttttgtg atgcaagacg cagattattt
    10501 aataaagacc tggcatccct cttgtggagc agcggcgtta cgtgccgaat tgatggccgg
    10561 atttgcgcat actgaatggt tgggattgac cgtatttgaa cattgttggc aggacgccga
    10621 caatatcgga tttgtcagtt ttgttgctcg atttaccgaa ggtggtaaaa caggtgcaat
    10681 aattgaacgt tcgcgatttt tgaaagaaaa cggtcaatgg tactatattg acggtacacg
    10741 tccgcagttt ggtcgcaacg atccctgccc ttgtggttca ggtaaaaaat ttaaaaagtg
    10801 ctgcggccaa taatggttga cggtacggtt tagcaaacac tctcaacaag gtttttccag
    10861 caatgcattc actccaacgt aaagttctgc gtactatttg tccggaccaa aaaggtctga
    10921 tcgcacgtat taccaatatt tgctacaagc acgagttaaa tatcgtacag aacaatgaat
    10981 ttgttgatca ccgtaccggg cgctttttta tgcgcacgga actggaaggg atttttaatg
    11041 attccaccct gctggcggat ctcgatagcg cattgccaga aggctccgtg cgtgagctga
    11101 atcctgccgg tcgtcgccgg atagtgattc tggtcactaa agaagcgcat tgccttggcg
    11161 atttgttgat gaaagccaat tacggcggcc tggatgtcga aatcgcggca gttattggta
    11221 accacgatac tttacgttct ctggttgagc gttttgatat tccgtttgag ctggtaagcc
    11281 atgaagggtt aacccgcaac gagcacgatc aaaagatggc ggatgccatt gatgcttatc
    11341 aacctgacta cgtggtgctg gcgaagtata tgcgggtatt aacgccggaa tttgtggcac
    11401 gcttcccgaa taagatcatc aatattcacc attcattcct gccagcgttt attggcgcac
    11461 gtccttatca ccaggcctat gaacgtggtg tgaagattat tggcgcaacc gctcactatg
    11521 tgaatgacaa tctggacgaa ggcccaatca tcatgcagga cgttattcat gtcgatcata
    11581 cctacacagc tgaagatatg atgcgcgcag gtcgtgacgt cgagaaaaac gtcttaagtc
    11641 gtgcactata caaagtactg gcacagcgcg tctttgttta cggtaatcga acgattattc
    11701 tttaatcgcc agcaaaaata actggttacc tttaatccgt tacggatgaa aattacgcaa
    11761 ccagttcatt tttctcaacg taacacttta cagcggcgcg tcatttgata tgatgcgccc
    11821 cgcttcccga taagggagca ggccagtaaa aagcattacc ccgtggtggg gttcccgagc
    11881 ggccaaaggg agcagactgt aaatctgccg tcatcgactt cgaaggttcg aatccttccc
    11941 ccaccaccat aattcaccac agcgatgtgg taacttcggt gagattgtga aagtttgcac
    12001 tcatcgggga agggtgagaa ccttcgacta aggttcgatt cgagcgaaag cgagagaacg
    12061 ttgccacagg caacggcccg aagggtgagg agcgaagcga cgaataatcc ttcccccacc
    12121 accatctcaa gcattacctc aaaatttgaa ttacccctgg tggggttccc gagcggccaa
    12181 agggagcaga ctgtaaatct gccgtcatcg acttcgaagg ttcgaatcct tcccccacca
    12241 ccatcacttt caaaagtccc tgaacttccc aacgaatccg caattaaata ttctgcccat
    12301 gcggggaagg atgagaagct tcgaccaagg ttcgactcga gcg
//
LOCUS       DAPOAV010000108        12089 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.108, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000108 DAPOAV010000000
VERSION     DAPOAV010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12089)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12089)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12089
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.108"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..95
                     /locus_tag="RN951_003781"
     CDS             <1..95
                     /locus_tag="RN951_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311911.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HDX2528715.1"
                     /translation="FHNDSTPRYDKSAADLAWQRTLKWFDKYLS"
     gene            241..1473
                     /gene="mdtM"
                     /locus_tag="RN951_003782"
     CDS             241..1473
                     /gene="mdtM"
                     /locus_tag="RN951_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001420685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtM"
                     /protein_id="HDX2528716.1"
                     /translation="MAGLKATHAATLFFPMALILYDFAAYLSTDLIQPGIINVVRDFN
                     ADVSLAPAAVSLYLAGGMALQWLLGPLSDRIGRRPVLITGALIFTLACAATMFTTSMT
                     QFLIARAIQGTSICFIATVGYVTVQEAFGQTKGIRLMAIITSIVLIAPIIGPLSGAAL
                     MHFVHWKVLFAIIAIMGFISFVGLLLAMPETVKRGAVSFSAKSVLRDFRNVFCNRQFL
                     FGAATISLSYIPMMSWVAVSPVILIDAGGLTTSQFAWTQIPVFGAVIVANAIVARFVK
                     DPTEPRFIWRAVPIQLVGLALLIIGNLLSPHVWLWSVLGTSLYAFGIGLIFPTLFRFT
                     LFSNNLPKGTVSASLNMVILMVMSVSVEIGRWLWFNGGRLPFHLLAVVAGVIVVFTLA
                     GLLNRVRQHQAAELAEEQ"
     gene            1514..2794
                     /locus_tag="RN951_003783"
     CDS             1514..2794
                     /locus_tag="RN951_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 domain-containing protein"
                     /protein_id="HDX2528717.1"
                     /translation="MNKLIELRRAKMLALSLLLIAAATFVVTLFLPPNFWVSGVKAIA
                     EAAMVGALADWFAVVALFRRVPIPIISRHTAIIPRNKDRIGENLGQFVQEKFLDTQSL
                     VALIRRHEPALLIGNWFSQPENARRVGQHLLQIMSGFLELTDDARIQRLLKRAVHRAI
                     DKVDLSGTSALMLESMTKNDRHQVLLDTLIAQLIALLQRDKSRKFIAQQIVRWLESEH
                     PLKAKILPTEWLGEHSAELVSDAVNSLLDDISRDRAHQIRHAFDRATFALIDKLKNDP
                     EMAARADAVKSYLKEDEAFNRYLSELWGDLREWLKVDINSEDSRVKERIARAGQWFGE
                     TLIADDALRASLNGHLEQAAHRVAPEFSAFLTRHISDTVKSWDARDMSRQIELNIGKD
                     LQFIRVNGTLVGGCIGLILYLLSQLPALFPLGNF"
     gene            2910..4061
                     /locus_tag="RN951_003784"
     CDS             2910..4061
                     /locus_tag="RN951_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418755.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase subunit D"
                     /protein_id="HDX2528718.1"
                     /translation="MSLVTDLPAIFDQFSEARQTGFLTVMDLKERGIPLVGTYCTFMP
                     QEIPMAAGAVVVSLCSTSDETIEEAEKDLPRNLCPLIKSSYGFGKTDKCPYFYFSDLV
                     VGETTCDGKKKMYEYMAEFKPVHVMQLPNSVKDDASRALWKAEMLRLQKTVEERFGHE
                     ISEDALRDAIALKNRERRALANFYHLGQLNPPALSGSDILKVVYGATFRFDKEALINE
                     LDAMTARVRQQWEEGQRLDPRPRILITGCPIGGAAEKVVRAIEENGGWVVGYENCTGA
                     KATEQCVAETGDVYDALADKYLAIGCSCVSPNDQRLKMLSQMVEEYQVDGVVDVILQA
                     CHTYAVESLAIKRHVRQQHNIPYIAIETDYSTSDVGQLSTRVAAFIEML"
     gene            4071..4838
                     /locus_tag="RN951_003785"
     CDS             4071..4838
                     /locus_tag="RN951_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001298028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528719.1"
                     /translation="MAYSIGIDSGSTATKGILLADGVITRRFLVPTPFRPATAITEAW
                     ETLREGLETTPFLTLTGYGRQLVDFADKQVTEISCHGLGARFLAPATRAVIDIGGQDS
                     KVIQLDDDGNLCDFLMNDKCAAGTGRFLEVISRTLGTNVEQLDSITENVTPHAITSMC
                     TVFAESEVISLRSAGVAPEAILAGVINAMARRSANFIARLSCEAPILFTGGVSHCQRF
                     THMLESHLGMPVQTHPDAQFAGAIGAAVIGQRQRKRA"
     gene            4835..5092
                     /locus_tag="RN951_003786"
     CDS             4835..5092
                     /locus_tag="RN951_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HDX2528720.1"
                     /translation="MKEYLFLFHSTVGVIQTRKALQAAGMTFRVSDIPRDLRGGCGLC
                     IWLTCPPGEEIQWVIPGHTESVYCQQDGGWRCIAHYGISPR"
     gene            5157..6017
                     /locus_tag="RN951_003787"
     CDS             5157..6017
                     /locus_tag="RN951_003787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418753.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiK family protein"
                     /protein_id="HDX2528721.1"
                     /translation="MTKSISLSKRIFVIVILFVIVAVCTFFVQSCARKSNHAASFQNY
                     HATIDGKEIAGITNNISSLTWSAQSNTLFSTINKPAAIVEMTTNGDLIRTIPLDFVKD
                     LETIEYIGDNQFVISDERDYAIYVISLTPNSEVKILKKIKIPLQESPTNCGFEGLAYS
                     RQDHTFWFFKEKNPIEVYKVNGLLSSNELHISKDKALQRQFTLDDVSGAEFNQQKNTL
                     LVLSHESRALQEVTLVGEVIGEMSLTKGSRGLSHNIKQAEGVAMDASGNIYIVSEPNR
                     FYRFTPQSSH"
     gene            6085..7263
                     /locus_tag="RN951_003788"
     CDS             6085..7263
                     /locus_tag="RN951_003788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2528722.1"
                     /translation="MPSSTHPVERFSFSTALFGMLVLTLGMGLGRFLYTPMLPVMMAE
                     GSFSFSQLSWIASGNYAGYLAGSLLFSFGAFHQPSRLRPFLLASALASGLLILAMAWL
                     PPFILVLLIRVLAGVASAGMLIFGSTLIMQHTRHPFVLAALFSGVGIGIALGNEYVLA
                     GLHFDLSSQTLWQGAGALSGMMLIALTLLMPSKKHAITPMPLAKTEQQIMSWWLLAIL
                     YGLAGFGYIIVATYLPLMAKDAVSPLLTAHLWTLVGLSIVPGCFGWLWAAKRWGALPC
                     LTANLLVQAICVLLTLASDSPLLLIISSLGFGGTFMGTTSLVMTIARQLSVPGNLNLL
                     GFVTLIYGIGQILGPALTSMLGNGTSALASATLCGAAALFIAALISTVQLFKLQVVTS
                     "
     gene            complement(7276..7830)
                     /gene="kptA"
                     /locus_tag="RN951_003789"
     CDS             complement(7276..7830)
                     /gene="kptA"
                     /locus_tag="RN951_003789"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2'-phosphotransferase"
                     /protein_id="HDX2528723.1"
                     /translation="MAKYNEKELADTSKFLSFVLRHKPEAIGIVLDREGWADIDKLIL
                     CAQKAGKRLTRALLDTVVATSDKKRFSYSSDGRCIRAVQGHSTSQVAISFAEKTPPQF
                     LYHGTASRFLDEIKKQGLIAGERHYVHLSADEATARKVGARHGSPVILTVKAQEMAKR
                     GLPFWQAENGVWLTSTVAVEFLEW"
     gene            8080..8763
                     /locus_tag="RN951_003790"
     CDS             8080..8763
                     /locus_tag="RN951_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418750.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528724.1"
                     /translation="MTQQGDAVAGELATEKVGIKGYLAFFLTIIFFSGVFSGTDSWWR
                     VFDFSVLNGSFGQLPGANGATTSFRGAGGAGAKDGFLFALELAPSVILSLGIISITDG
                     LGGLRAAQQLMTPVLKPLLGIPGICSLALIANLQNTDAAAGMTKDLAQEGEITERDKV
                     IFAAYQTSGSAIITNYFSSGVAVFAFLGTSVIVPLAVIQVFKFVGANILRVWLNFEER
                     RNPTQGAQA"
     gene            8760..9221
                     /locus_tag="RN951_003791"
     CDS             8760..9221
                     /locus_tag="RN951_003791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HDX2528725.1"
                     /translation="MTTQVRKNVMDMFIDGARRGFTIATTNLLPNVVMAFVIIQALKI
                     TGLLDWVGHICEPVMALWGLPGEAATVLLAALMSMGGAVGVAASLATAGALTGHDVTV
                     LLPAMYLMGNPVQNVGRCLGTAEVNAKYYPHIITVCVINALLSIWVMQLIV"
     gene            9234..10406
                     /gene="iadA"
                     /locus_tag="RN951_003792"
     CDS             9234..10406
                     /gene="iadA"
                     /locus_tag="RN951_003792"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HDX2528726.1"
                     /translation="MIDYTAAGFTLLQGAHLYAPEDRGICDVLVANGKIIAVASNIPS
                     DIVPDCTVVDLSGQILCPGFIDQHVHLIGGGGEAGPTTRTPEVALSRLTEAGVTSVVG
                     LLGTDSISRHPESLLAKTRALNEEGISAWMLTGAYHVPSRTITGSVEKDVAIIDRVIG
                     VKCAISDHRSAAPDVYHLANMAAESRVGGLLGGKPGVTVFHMGDSKKALQPVYDLLEN
                     CDVPISKLLPTHVNRNVPLFEQALEFARKGGTIDITSSIDEPVAPAEGIARAVQAGIP
                     LARVTLSSDGNGSQPFFDDEGNLTHIGVAGFETLLETVQVLVKDYDFSISDALRPLTS
                     SVAGFLNLSGKGEILPGNDADLLVMTPELRIEQVYARGKLMVKDGKACVKGTFETA"
     gene            10471..11382
                     /gene="hypT"
                     /locus_tag="RN951_003793"
                     /gene_synonym="qseD"
     CDS             10471..11382
                     /gene="hypT"
                     /locus_tag="RN951_003793"
                     /gene_synonym="qseD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypochlorite stress DNA-binding transcriptional
                     regulator HypT"
                     /protein_id="HDX2528727.1"
                     /translation="MDDCGAVLHNIETKWLYDFLTLEKCRNFSQAAVSRYVSQPAFSR
                     RIRALEQAIGVELFNRQVTPLQLSEQGKIFHSQIRHLLQQLESNLAELRGGSDYAQRK
                     IKIAAAHSLSLGLLPSIISQMPPLFTWAIEAIDVDEAADKLREGQSDCIFSFHDEDLL
                     EAPFDHIRLFESQLFPVCASDEHGEALFNLAQPHFPLLNYSRNSYMGRLINRTLTRHS
                     ELSFSTFFVSSMSELLKQVALDGCGIAWLPEFAIQQEIRSGQLVVLNRDELVIPIQAY
                     AYRMNTRMNPVAERFWRELRELEIVLS"
     gene            complement(11375..11767)
                     /gene="iraD"
                     /locus_tag="RN951_003794"
     CDS             complement(11375..11767)
                     /gene="iraD"
                     /locus_tag="RN951_003794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418746.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraD"
                     /protein_id="HDX2528728.1"
                     /translation="MMRQSRQAVLPEISGNKTSSLRKSICSDLLTLFNSPHSALPSLL
                     VSGMPEWQVHNQSDKHLQSWYCRQLRSALLFHEPRIAALQVNLKEAYSHTLAISLEIM
                     LYHDDEPLTFDLVWDNGGWRSATLENVS"
     gene            complement(11764..11847)
                     /gene="idlP"
                     /locus_tag="RN951_003795"
     CDS             complement(11764..11847)
                     /gene="idlP"
                     /locus_tag="RN951_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iraD leader peptide IdlP"
                     /protein_id="HDX2528729.1"
                     /translation="MENEHQYSGARCSGQAAYVAKRQECAK"
BASE COUNT         2738 a         3066 c         3148 g         3137 t
ORIGIN      
        1 gattccataa tgattccacg ccccgttatg acaaatctgc cgccgatctt gcctggcaaa
       61 ggacactgaa atggtttgat aaatatctct cctgataggt ttatctctta cgggattacg
      121 tcttaaacaa gcatgaaaaa atagcgtgcg caaaagtcgt tctttgccta aaatatcgct
      181 atatatggcg atatatagcg aatgaagtga acgatgaata accattttgg taaaggctta
      241 atggcgggat taaaagcaac gcatgccgcc acgctgtttt tcccgatggc gttgattttg
      301 tatgattttg ccgcgtacct gtcgacggac ctgattcagc cggggatcat taatgtggtc
      361 cgtgatttta atgccgatgt cagtctggcc ccggcagccg tcagtctcta tctcgcgggc
      421 ggtatggcgt tacagtggct gctggggccg ctttccgaca ggattggccg caggccggtg
      481 ctgattaccg gggcgctaat atttaccctt gcctgcgctg cgacaatgtt cacaacgtct
      541 atgacacagt ttcttatcgc gcgtgcaatt cagggcacca gtatctgttt tattgccacc
      601 gttggttatg tcacggtgca ggaggcgttc ggccagacaa aagggatcag gttgatggcg
      661 attatcacct ccatcgtact gattgcgccg attatcggcc cgctttccgg cgcagctctg
      721 atgcactttg tacactggaa agtccttttt gccatcattg cgattatggg ttttatctca
      781 tttgttggct tactgctggc gatgccagag acggtgaagc gcggcgcggt ttcatttagc
      841 gccaaaagcg tcttgcgcga ttttcgtaat gtcttttgca atcggcagtt cctctttggt
      901 gcagcaacca tctctttaag ctatatccca atgatgagtt gggtggctgt ctcgccggtg
      961 atcctgattg acgcaggcgg cttaacgacc tcgcagttcg cctggacaca gattccggtg
     1021 ttcggcgcgg tgattgtcgc gaatgccatc gtggcgcgtt tcgttaaaga tccgaccgaa
     1081 ccgcgcttta tctggcgtgc cgtacccatt caactggttg gcctcgcgct gttgattatc
     1141 ggcaatctgc tgtcaccgca cgtctggctg tggtcggtgc tgggcaccag tttgtatgct
     1201 ttcgggattg gtttgatctt cccgacctta ttccgcttta cgctgttttc caataactta
     1261 ccgaaaggga ccgtctccgc atcgctgaat atggtgatcc tgatggtgat gtctgtctcg
     1321 gtcgaaatcg gccggtggct gtggtttaac ggcggtcgct tgccgtttca tctgttagcc
     1381 gtcgtggcgg gcgttatcgt cgttttcacc ctggcgggat tgcttaatcg cgtgcgccaa
     1441 catcaggctg ccgagctggc agaggagcag tgatttttgc gcgatcctgc cgtcaggctc
     1501 tattcttaac gttatgaata aactcattga actcagacgc gccaaaatgt tggcgctctc
     1561 tttactgctt atcgccgctg ctacctttgt cgttacgctg tttttgccgc ccaatttttg
     1621 ggtgagcggc gtgaaggcga ttgctgaagc ggcgatggtc ggcgcgctgg cggactggtt
     1681 tgcggtggtg gcgctgtttc gccgcgtgcc gattccgatc atttctcgcc atacggcgat
     1741 tatcccgcgt aataaagacc ggattggcga aaatctcggc cagttcgtgc aggaaaaatt
     1801 tcttgatact caatccctgg tggcattgat tcgacgccac gaaccggcgt tgctgattgg
     1861 caactggttt agccagccag aaaacgcccg ccgcgttggt cagcatctgt tgcagatcat
     1921 gagcggtttt ctcgaactta ccgatgatgc gcgtattcag cgcctgctta agcgcgcggt
     1981 ccatcgggcg attgataagg tcgatctttc cggcaccagt gcgttgatgc tggagagtat
     2041 gaccaaaaac gatcgtcatc aggtgctgct ggatacgctg atcgcacagt tgatcgccct
     2101 tctccagcgc gataaatcgc gcaagtttat cgcccagcaa attgttcgct ggctggagag
     2161 cgagcatcca ctgaaagcca aaattctccc caccgaatgg ttgggcgaac atagcgcgga
     2221 gttggtttct gacgcggtga attctttgct tgatgatatt agtcgcgatc gtgcgcatca
     2281 gatccgccat gcgtttgatc gcgccacctt cgccctgatc gacaagctga aaaacgatcc
     2341 ggaaatggca gcgcgagccg atgccgtaaa aagctatctg aaagaagatg aagcttttaa
     2401 tcgctatctc agtgaattgt ggggggattt acgggaatgg ctgaaagtgg atatcaacag
     2461 tgaagattct cgtgtgaaag aacgcatcgc acgagcgggt caatggtttg gcgaaacgtt
     2521 aattgccgat gatgccttgc gggcgtcgtt aaatggtcat cttgaacaag ccgcgcaccg
     2581 cgtcgcgcct gagttttccg cattcctgac gcgccacatc agcgatacgg taaaaagctg
     2641 ggatgcgcgg gatatgtcgc ggcaaataga gttaaatatc ggcaaagatc tgcagtttat
     2701 tcgtgtcaac ggtacgctgg ttggcggttg tattgggcta attttatatt tgctgtcgca
     2761 gctcccggcc ttgttccccc tcggcaattt ttagaaatcc atgaaaaact aagtggctaa
     2821 ccgcgagaga gatcaaataa accatactaa aagaatggta ataatgtggc ctcttttcat
     2881 tatctcccgt ggtacgggga aggaaaatca tgtcacttgt caccgatcta cccgccattt
     2941 tcgatcagtt ctctgaagct cgccagacag gctttctcac cgtcatggat ctcaaggagc
     3001 gcggcattcc gctggttggc acttactgca cctttatgcc gcaagagatc ccgatggcag
     3061 ccggtgcggt tgtggtttcg ctctgttcca cctctgatga aaccattgaa gaagcggaga
     3121 aagatctgcc gcgcaacctc tgcccgctga ttaaaagcag ctacggcttc ggcaaaaccg
     3181 ataaatgccc ctacttctac ttttcggatc tggtggtcgg tgaaaccacc tgcgacggca
     3241 aaaagaaaat gtatgaatac atggcggagt ttaagcctgt tcatgtgatg caattgccca
     3301 acagcgttaa ggacgatgcc tcgcgtgcgt tatggaaagc cgagatgctg cgcttgcaaa
     3361 aaacggtaga agaacgtttt gggcacgaga ttagcgaaga tgctctgcgc gatgccattg
     3421 cgctgaaaaa ccgcgaacgt cgcgcactgg ctaattttta tcatcttggg cagttaaatc
     3481 ctccggcgct tagcggcagc gacattctga aagtggttta cggcgcaacc ttccggttcg
     3541 ataaagaggc gttgatcaat gaactggatg caatgaccgc ccgcgttcgt cagcagtggg
     3601 aagaaggcca gcgactggac ccgcgtccgc gcattttaat caccggctgc ccgattggcg
     3661 gcgcagcaga aaaagtggtg cgcgcgattg aagagaatgg cggctgggtt gtcggttatg
     3721 aaaactgcac cggggcgaaa gcgaccgagc aatgcgtggc agaaacgggc gatgtctacg
     3781 acgcgctggc ggataaatat ctggcgattg gctgctcctg tgtttcgccg aacgatcagc
     3841 gcctgaaaat gctcagccag atggtggagg aatatcaggt cgatggcgta gttgatgtga
     3901 ttttgcaggc gtgccatacc tacgcggtgg aatcgctggc gattaaacgt catgtgcgcc
     3961 agcagcacaa cattccttat atcgctattg aaacagacta ctccacctcg gatgtcgggc
     4021 agctcagtac ccgtgtcgcg gcctttattg agatgctgta aggagtggca gtggcatatt
     4081 cgattggcat tgattccggc tcaaccgcca ccaaagggat cttactggca gacggcgtga
     4141 ttacgcgccg tttcctcgtt ccaacaccct ttcgcccggc aacagcaatt actgaagcct
     4201 gggaaactct gcgcgaaggg ttagaaacaa cgccgtttct gacgctcacc ggctacggac
     4261 ggcaactggt ggattttgcc gataaacagg tgacggaaat ctcctgtcac gggctgggcg
     4321 cacggtttct tgcgccagca acgcgcgcag taatcgacat cggtggtcag gacagcaaag
     4381 tgattcagct tgatgatgac ggtaacctgt gcgatttcct gatgaatgac aaatgcgcgg
     4441 cgggcaccgg gcgtttcctg gaggtgatct cgcgcacgct tggcaccaac gtcgaacagc
     4501 tcgacagcat taccgaaaat gtcacgccgc acgccatcac gagtatgtgc acagtatttg
     4561 ccgaatcaga agtgatcagc ctgcgctcag cgggcgtcgc gccagaagcg attctcgccg
     4621 gagtgattaa cgcgatggcg cggcggagtg ccaatttcat tgctcgtctc tcctgtgaag
     4681 cgccgattct gtttactggt ggcgttagcc actgtcaaag gtttacccac atgctggaaa
     4741 gccatctggg aatgccggta caaactcacc ctgatgcgca attcgctggt gcaattggcg
     4801 cggcggtgat cggtcagcgg cagagaaaac gcgcatgaaa gagtatctat ttttatttca
     4861 ctccacggtc ggcgtcatac aaacccgcaa ggcgttgcag gcagcgggca tgacttttcg
     4921 cgtcagcgat attccccgtg atttacgcgg cggctgcggg ttatgcattt ggctgacctg
     4981 tccgcctggc gaggaaattc aatgggtgat ccctgggcat acggaatcag tttattgtca
     5041 gcaggatggt ggctggcgct gcattgcaca ttacgggatt tctccgcgtt aaggattcat
     5101 taagatcgct acgtatactt ctcgatatct tattgatttg ccttaaaggg attaccgtga
     5161 caaaaagtat ttcgttaagt aaacgcatct tcgttattgt gattcttttt gtcattgtgg
     5221 cagtgtgtac tttcttcgtg caatcttgcg cccgtaaaag caatcatgca gcatcatttc
     5281 agaattacca cgccaccatt gacggcaaag aaattgcagg cataacgaat aatatctctt
     5341 cgctgacctg gtcggcacaa agcaatactc tttttagcac tatcaacaaa cctgccgcca
     5401 ttgttgaaat gaccaccaat ggtgatttga tccgcacaat tcctctggat tttgttaagg
     5461 atctcgagac gatcgaatac attggcgata atcagtttgt cattagcgat gagcgcgatt
     5521 atgccattta tgtgatttca ctgaccccaa actcggaagt aaaaatcctc aaaaaaataa
     5581 aaatcccgct gcaggaatcc ccaaccaatt gcggttttga aggattggcc tattctcgcc
     5641 aggatcacac tttctggttt tttaaagaga aaaacccgat tgaggtctac aaagttaacg
     5701 ggctattaag tagcaatgaa ttgcacatca gcaaagacaa ggcactacaa cggcaattta
     5761 ctttagatga tgtgtccggc gcagaattta accaacaaaa aaatacgctt ctggtgctgt
     5821 ctcatgaatc tcgcgcactc caggaagtaa cgctggttgg cgaggttatc ggtgaaatgt
     5881 cactaaccaa aggcagtcga ggtttgtcgc ataacatcaa acaggccgaa ggggttgcga
     5941 tggatgcctc tggtaatatt tatatcgtta gcgaaccaaa tcgtttttat cgctttaccc
     6001 ctcaatcatc gcattaacag gctggcatgc ttcacctttt tgttattaac ttgttaacaa
     6061 caaaaatgac aaacaaggtt aaacatgcct tcgtccacgc atcccgtaga acgcttttct
     6121 ttcagcaccg cgcttttcgg gatgctggtt ctgaccttag gtatgggttt aggccgcttc
     6181 ctttatacgc ctatgttgcc cgtcatgatg gcggaaggat cgttttcatt tagccagctc
     6241 tcgtggattg ccagcggcaa ctatgcgggg tatctggctg gcagtctgct attttctttt
     6301 ggcgcatttc accagccatc gcgcctgcgc ccatttctgt tggcttctgc cctggcgagc
     6361 gggttgttga tcctcgcaat ggcatggttg ccgccattta ttctggtgtt attgattcgc
     6421 gtcctggcgg gtgtcgccag cgccggtatg ctgatttttg gttcgacgct gattatgcag
     6481 cacacgcgcc atccttttgt gctggcagct ttgttttctg gcgttggcat tggcatcgca
     6541 ctgggcaatg aatatgttct ggcaggcctg cattttgacc tctcctcgca aacgttatgg
     6601 caaggcgccg gggcgctttc tggcatgatg ctgattgcac ttacgctttt aatgccctcg
     6661 aaaaaacacg ccatcacacc aatgccattg gcaaaaacgg agcaacagat aatgagctgg
     6721 tggttactgg ctattctgta cggcctggcg ggatttggtt atatcatcgt cgcgacttac
     6781 ctgccgctca tggcgaaaga tgcagtctca ccattgttaa ccgcccatct ctggacgtta
     6841 gtcggcttat caattgtgcc tggttgcttt ggctggctat gggcagcaaa acgttggggg
     6901 gctttgccct gcctgacggc gaatttgctg gtgcaggcta tctgtgtgct gcttactctc
     6961 gccagcgact cgcctctctt gcttatcatc agcagtcttg gttttggcgg tacctttatg
     7021 ggcacgacat ctctggtgat gactatcgcc cgccaactga gcgtaccggg aaatctcaat
     7081 cttttaggct ttgtgacgct catttacggc attgggcaaa tcctcggccc ggcgctgacc
     7141 agtatgctcg gcaatggaac atcggcgctt gccagcgcca ctctctgcgg cgcggcggcg
     7201 ttgtttattg ctgcgcttat cagcacagtg caattattta agctacaagt ggtcacttca
     7261 tgagggaagt ttcccttacc actcaagaaa ctcaaccgca accgttgatg tcagccagac
     7321 cccgttttcc gcttgccaga aagggaggcc tcgtttcgcc atttcctgtg ctttgacggt
     7381 taaaataacc ggcgatccgt gtcttgctcc cactttgcgt gccgttgctt catcagcaga
     7441 gagatgtacg tagtgacgct cacctgcaat cagcccctgt ttttttatct cgtcaaggaa
     7501 acggcttgcc gtaccgtggt agagaaactg tggcggtgtt ttttcggcaa aggaaatagc
     7561 gacctgcgaa gtcgaatgcc cctgaaccgc gcggatgcac ctaccatcac tggaataact
     7621 aaaacgcttt ttatcgctgg tggcaaccac agtatccagc aatgcacggg ttaaccgctt
     7681 gcccgctttt tgggcacaaa gtatgagctt atcgatatcc gcccatcctt cacggtccag
     7741 tacgatacca atcgcctccg gtttgtgtcg gaggacaaaa cttaaaaact tgctcgtatc
     7801 cgccagctct ttttcgttgt actttgccat ctcgttttcg tccctggatt ttctgttttt
     7861 atttacttat gtcattgtca ctgggtttat gaatttactg caactcaatc cagcgcagaa
     7921 ccttttcccc atagcgtaat ttttccgcta tgcaaaaaac gcatagccag aaacatactt
     7981 gcattttccc catacccaca tggctgataa ggtttttcag ctccaggaat tttcctggct
     8041 caagcaacac acaaacacaa aaaaacaatg gggattgtta tgacacaaca aggggatgct
     8101 gtagccgggg agctggcgac agaaaaagtg ggcattaaag ggtatctggc tttttttctc
     8161 accataatct ttttttccgg tgttttttca ggaacagaca gctggtggcg cgtttttgat
     8221 ttttccgtgc tgaacggatc gtttgggcag ttacctggtg cgaatggagc caccacctca
     8281 tttcgcgggg cgggtggcgc gggggctaaa gatggctttc tctttgcgct ggagctggca
     8341 ccgtcagtca ttctctctct ggggattatt tcaattaccg atggtcttgg tggattacgc
     8401 gccgcgcagc agttaatgac gcctgtgcta aaaccgttgt tgggcattcc agggatctgc
     8461 tcgctggcgc tgatcgctaa cctgcaaaac actgatgccg ccgccggtat gaccaaagat
     8521 ctggcgcagg aaggtgaaat taccgaacgc gataaagtga ttttcgccgc atatcaaacc
     8581 agcggtagcg ccatcatcac caactacttc tcttccggcg tcgcggtgtt cgcctttctg
     8641 ggcacgtccg taatcgtacc tttagccgtc atccaggtgt ttaaatttgt cggagccaac
     8701 attttgcgcg tctggcttaa cttcgaagaa cgtcgcaacc caacgcaagg agcgcaagca
     8761 tgacaactca ggtccgcaaa aacgtcatgg atatgtttat cgatggtgcg cgccgtggct
     8821 ttactatcgc cacgaccaac ctgctgccaa acgtggtgat ggcgtttgtc atcattcagg
     8881 cgctgaaaat taccggcctg ctcgactggg tggggcatat ctgtgaaccc gtaatggcgc
     8941 tgtggggatt acccggtgaa gcggcaaccg tccttttagc cgcattaatg agtatgggtg
     9001 gcgcagtcgg tgttgccgcc agtctggcaa ccgctggcgc attaaccggt cacgatgtca
     9061 ccgttttact gcccgcgatg tatttaatgg gcaacccggt gcaaaatgtc ggtcgctgcc
     9121 tggggacagc cgaagtgaat gccaaatatt acccgcatat cattacggtc tgcgtgatta
     9181 acgcattgct gtcgatctgg gttatgcagc ttattgttta acaaggagtt accatgattg
     9241 attataccgc agccggtttt accctgctgc agggagcgca tttgtatgcg ccggaagatc
     9301 ggggaatttg cgatgtcctc gtcgctaacg gcaaaattat cgccgttgcc agtaatatcc
     9361 cctctgacat tgtaccggac tgcacggttg tcgatctcag cgggcagatc ctctgcccag
     9421 gttttattga tcaacacgtc catttgattg gcggtggcgg cgaagcaggt cccacgacgc
     9481 gcacgccgga agtggcgcta agtcgcctga cggaagcggg cgtcacgtca gtggttggtc
     9541 tgctgggcac cgactctatc tctcgccacc cggaatccct gctcgccaag acccgtgcgc
     9601 tcaatgaaga aggcatcagc gcctggatgc tgaccggcgc ttatcatgtc ccttcccgca
     9661 ccattacggg ttccgtggaa aaagacgtgg cgattattga tcgtgtgatt ggcgtgaaat
     9721 gcgccatctc tgatcaccgt tctgccgcac cggacgttta tcacctggcc aatatggcgg
     9781 cagaatcccg cgttggcggt ttgctcggcg gtaaacctgg cgtcaccgtg ttccacatgg
     9841 gcgacagtaa aaaggcgtta cagcctgtct atgacctgct ggaaaactgc gatgtgccga
     9901 tcagcaagct gctgccgacc cacgttaacc gcaacgtacc gttgtttgag caggcgctgg
     9961 agttcgcgcg caaaggcggc accatcgata tcaccagcag cattgacgaa ccggtcgccc
    10021 ctgccgaagg tattgcccgc gccgttcagg cgggtattcc gctggcacgc gtcaccctca
    10081 gctccgacgg caacggtagc cagccgttct tcgatgacga agggaattta acccatatcg
    10141 gtgttgcagg ttttgaaacg ttgctggaaa ccgtgcaggt gctggtcaaa gactatgatt
    10201 tcagtatcag cgatgccctg cgcccgctca ccagtagcgt agccggtttc cttaacctga
    10261 gcgggaaagg cgaaattctg ccaggcaatg acgcagactt actggtcatg acgccagaat
    10321 tgcgcattga gcaggtatac gctcgcggca aactgatggt caaagacggc aaagcctgcg
    10381 tgaaaggaac gtttgaaacg gcataaacgg ttgtcagccg cccgaatgga cgtagaatgc
    10441 ccgcaagggc ggctgacaga gtaaaacgta atggatgact gtggtgcggt tttgcataat
    10501 attgaaacca aatggcttta tgattttctg accctggaaa aatgccgcaa tttttcccag
    10561 gcggcagtca gtcgttacgt ctcgcaaccg gcattcagcc gccgcatccg cgcgctggaa
    10621 caggcgattg gcgttgaatt gtttaaccgc caggtgacgc cgctgcaact ctcggaacaa
    10681 gggaaaatct ttcattcgca gatccgccat ctgttgcaac agttagaaag caacctggca
    10741 gagctgcgtg gcggcagcga ttacgcgcaa cgtaaaatca agatagccgc tgcacattct
    10801 ctttccctcg gtctgttacc gtccattatc agccagatgc cgccgctctt tacctgggca
    10861 attgaagcca ttgatgttga tgaagcagcc gataaactgc gtgaagggca aagtgactgt
    10921 attttttcct ttcacgacga agatttgctg gaagcgccgt ttgaccacat tcgcttattt
    10981 gaatctcaat tgttccctgt ctgcgccagt gacgaacacg gagaagcact ttttaacctc
    11041 gcgcagccac actttccgtt actgaattac agccgcaact cctacatggg gcgattgatt
    11101 aatcgcaccc tgacgcgcca cagtgagtta agtttcagca ccttttttgt ctcttcgatg
    11161 agcgagcttt taaagcaggt tgccctcgac ggctgtggga ttgcctggct gccggagttc
    11221 gccatccaac aagaaattcg cagcgggcag ctcgttgtac tgaatcggga cgaactggtg
    11281 atcccgattc aggcctatgc ataccgaatg aatacccgca tgaatccagt tgccgaacgc
    11341 ttctggcgtg aactgcgcga gctggagatt gtacttagct gacattctcg agcgtcgcac
    11401 tacgccaacc gccattatcc cagaccagat caaacgttag cggttcatcg tcgtggtaca
    11461 gcattatctc aaggctgatc gccagcgtgt ggctgtacgc ttctttcaga ttgacctgca
    11521 acgccgcaat ccgtggctca tgaaataaca gtgcagaacg cagctgacgg caataccagc
    11581 tctggagatg tttgtcgctc tggttatgca cttgccactc gggcatgcct gaaacaagta
    11641 atgacggtaa tgccgaatga ggagaattaa aaagagtgag gagatcgcta catattgatt
    11701 tacgcagcga tgacgtttta ttgcctgaaa tttcaggtaa aacagcctga cgtgattggc
    11761 gcatcatttt gcgcactcct gacgtttagc aacatatgcg gcttgccctg aacaccgggc
    11821 accactgtat tgatgctcat tttccatagc cattcccttt tgttcattac atccatgtca
    11881 gtctgagaca ggcctgaatc ctgtcagcaa agtataaaac cttacttgcc tatgaatatc
    11941 tactgacttt tcaggaaaaa agtcatgatt tgataaaaat catcaaactc aaaaaaaaac
    12001 cgctagtata ttctgaatat tccgaatagt tacgtagatg aaaatacttg tcaccaccgc
    12061 tacttaattc cggtgtgaaa ttatttatt
//
LOCUS       DAPOAV010000109        11983 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.109, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000109 DAPOAV010000000
VERSION     DAPOAV010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11983
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.109"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            57..659
                     /locus_tag="RN951_003796"
     CDS             57..659
                     /locus_tag="RN951_003796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416376.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebB family permuted papain-like enzyme"
                     /protein_id="HDX2528730.1"
                     /translation="MNINYPAEYEIGDIVFTCIGAALFGQISAASNCWSNHVGIIIGH
                     NGEDFLVAESRVPLSTITTLSRFIKRSSNQRYAIKRLDAGLTERQKQRIVEQVPSRLR
                     KLYHTGFKYESSRQFCSKFVFDIYKEALCIPVGEIETFGELLNSNPNAKLTFWKFWFL
                     GSIPWERKTVTPASLWHHPGLVLIHAEGVETPQPELTEAV"
     gene            complement(661..1182)
                     /gene="ruvC"
                     /locus_tag="RN951_003797"
     CDS             complement(661..1182)
                     /gene="ruvC"
                     /locus_tag="RN951_003797"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005068993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HDX2528731.1"
                     /translation="MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSR
                     LKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEY
                     AARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQM
                     SESRLNLARGRLR"
     gene            complement(1217..1957)
                     /locus_tag="RN951_003798"
     CDS             complement(1217..1957)
                     /locus_tag="RN951_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDX2528732.1"
                     /translation="MAGHSKWANTRHRKAAQDAKRGKIFTKIIRELVTAAKLGGGDPD
                     ANPRLRAAVDKALSNNMTRDTLNRAIARGVGGDDDANMETIIYEGYGPGGTAIMIECL
                     SDNRNRTVAEVRHAFSKCGGNLGTDGSVAYLFSKKGVISFEKGDEDTIMEAALEAGAE
                     DVVTYDDGAIDVYTAWEEMGKVRDALEAAGLKADSAEVSMIPSTKADMDAETAPKLMR
                     LIDMLEDCDDVQEVYHNGEISDEVAATL"
     gene            complement(1986..2438)
                     /gene="nudB"
                     /locus_tag="RN951_003799"
     CDS             complement(1986..2438)
                     /gene="nudB"
                     /locus_tag="RN951_003799"
                     /EC_number="3.6.1.67"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate diphosphatase"
                     /protein_id="HDX2528733.1"
                     /translation="MKDKVYKRPVSILVVIYAQDTKRVLMLQRRDDPDFWQSVTGSVE
                     EGETAPQAAMREVKEEVTIDVVAEQLTLIDCQRTVEFEIFSHLRHRYAPGVTRNTESW
                     FCLALPHERQIVFTEHLAYKWLDAPAAAALTKSWSNRQAIEQFVINAA"
     gene            complement(2556..4328)
                     /gene="aspS"
                     /locus_tag="RN951_003800"
     CDS             complement(2556..4328)
                     /gene="aspS"
                     /locus_tag="RN951_003800"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HDX2528734.1"
                     /translation="MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGI
                     VQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTII
                     NRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDI
                     ETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRD
                     EDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAE
                     RRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQI
                     DEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEDILDRTAAQDGDMI
                     FFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHP
                     FTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEE
                     EQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTE
                     APSFANPTALAELSIQVVKKAENN"
     gene            4638..5204
                     /locus_tag="RN951_003801"
     CDS             4638..5204
                     /locus_tag="RN951_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416381.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDX2528735.1"
                     /translation="MLELNAKTTALVVIDLQEGILPFAGGPHTADEVVNRAGKLAAKF
                     RASGQPVFLVRVGWSADYAEALKQPVDAPSPAKVLPENWWQHPAALGATDSDIEIIKR
                     QWGAFYGTDLELQLRRRGIDTIVLCGISTNIGVESTARNAWELGFNLVIAEDACSAAS
                     AEQHNNSINHIYPRIARVRSVEEILNAL"
     gene            5201..6019
                     /locus_tag="RN951_003802"
     CDS             5201..6019
                     /locus_tag="RN951_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HDX2528736.1"
                     /translation="MIYIGLPQWSHPKWVRLGITSLEEYARHFNCVEGNTTLYALPKP
                     EVVLRWREQTTDDFRFCFKFPATISHQAALRHCDDLVTEFLTRMSPLAPRIGQYWLQL
                     PATFGPRELPALWHFLDSLPGEFNYGVEVRHPQFFAKGEEEQTLNRGLHQRGVNRVIL
                     DSRPVHAARPHSEAIRDAQRKKPKVPVHAVLTATNPLIRFIGSDDMTQNRELFQVWLQ
                     KLAQWHQTTTPYLFLHTPDIAQAPELVHTLWEDLRKTLPEIGAVPAIPQQSSLF"
     gene            6072..6467
                     /locus_tag="RN951_003803"
     CDS             6072..6467
                     /locus_tag="RN951_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310606.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MAPEG family protein"
                     /protein_id="HDX2528737.1"
                     /translation="MVSALYAVLSALLLMKFSFDVVRLRMQYRVAYGDGGFSELQSAI
                     RIHGNAVEYIPIAIVLMLFMEMNGAETWMVHICGIVLLAGRLMHYYGFHHRLFRWRRS
                     GMSATWCALLLMVLANLWYMPWELVFSLR"
     gene            6508..7251
                     /gene="cmoA"
                     /locus_tag="RN951_003804"
     CDS             6508..7251
                     /gene="cmoA"
                     /locus_tag="RN951_003804"
                     /EC_number="2.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy-S-adenosyl-L-methionine synthase CmoA"
                     /protein_id="HDX2528738.1"
                     /translation="MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIIS
                     MIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRRHI
                     DAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGAL
                     VLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARL
                     HNAGFEHSELWFQCFNFGSLVALKAEDAA"
     gene            7248..8219
                     /gene="cmoB"
                     /locus_tag="RN951_003805"
     CDS             7248..8219
                     /gene="cmoB"
                     /locus_tag="RN951_003805"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic
                     acid(34) synthase CmoB"
                     /protein_id="HDX2528739.1"
                     /translation="MIDFGNFYSLIAKNHLSHWLETLPAQIANWQREQQHGLFKQWSN
                     AVEFLPEIKPYRLDLLHSVTAESEEPLSAGQIKRIETLMRNLMPWRKGPFSLYGVNID
                     TEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFLCQ
                     FEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVN
                     EGELVLETLVIDGDENTVLVPGDRYAQMRNVYFIPSALALKNWLKKCGFVDIRIADVS
                     VTTTEEQRRTEWMVTESLADFLDPHDPGKTVEGYPAPKRAVLIARKP"
     gene            complement(8384..10813)
                     /gene="torZ"
                     /locus_tag="RN951_003806"
     CDS             complement(8384..10813)
                     /gene="torZ"
                     /locus_tag="RN951_003806"
                     /EC_number="1.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416386.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethylamine N-oxide reductase TorZ"
                     /protein_id="HDX2528740.1"
                     /translation="MTLTRREFIKHSGIAAGALVVTSAAPLPAWAEEKGGKILTAGRW
                     GAMNVEVKDGKIVSSTGALAKTIPNSLQSTAADQVHTTARIQHPMVRKSYLDNPLQPA
                     KGRGEDTYVQVSWEQALKLIHEQHDRIRKANGPSAIFAGSYGWRSSGVLHKAQTLLQR
                     YMNLAGGYSGHSGDYSTGAAQVIMPHVVGSVEVYEQQTSWPLILENSQVVVLWGMNPL
                     NTLKIAWSSTDEQGLEYFHQLKKSGKPVIAIDPIRSETIEFFDDNATWIAPNMGTDVA
                     LMLGIAHTLMTQGKHDKVFLEKYTTGYPQFEEYLTGKSDNTPKSAVWAAEITGVPEAQ
                     IVKLAELMAANRTMLMAGWGIQRQQYGEQKHWMLVTLAAMLGQIGTPGGGFGFSYHYS
                     NGGNPTRVGGVLPEMSAAIAGHASEAADDGGMTAIPVARIVDALENPGGKYQHNGKEQ
                     TYPNIKMIWWAGGGNFTHHQDTNRLIKAWQKPEMIVVSECYWTAAAKHADIVLPITTS
                     FERNDLTMTGDYSNQHIVPMKQAVAPQFEARNDFDVFADLAELLKPGGKEIYTEGKDE
                     MAWLKFFYDAAQKGARAQRVTMPMFNAFWQQNKLIEMRRSEKNEQYVRYGDFRADPVK
                     NALGTPSGKIEIYSKTLEKFGYKDCPAHPTWLAPDEWKGTADEKQLQLLTAHPAHRLH
                     SQLNYAELRKKYAIADREPITIHTEDAARFGIANGDLVRVWNKRGQILTGAVVTDGIK
                     KGVVCVHEGAWPDLENGLCKNGSANVLTADIPSSQLANACAGNSALVYIEKYTGNAPK
                     LTAFDQPAVQA"
     gene            complement(10838..11938)
                     /locus_tag="RN951_003807"
     CDS             complement(10838..11938)
                     /locus_tag="RN951_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NapC/NirT family cytochrome c"
                     /protein_id="HDX2528741.1"
                     /translation="MRGKKRIGLLFLLIAVVVGGGGLLLAQKALHKTSDTAFCLSCHS
                     MSKPFEEYQGTVHFSNQKGIRAECADCHIPKSGMDYLFAKLKASKDIYHEFVSGKIDS
                     DDKFEAHRQEMAETVWKELKATDSATCRSCHSFDAMDIASQSESAQKMHNKAQKDSET
                     CIDCHKGIAHFPPEIKMDDNAAHELESQAATSVTNGAHIYPFKTSHIGELATVNPGTD
                     LTVVDASGKQPIVLLQGYQMQGSENTLYLAAGQRLALATLSEEGIKALTVNGEWQADE
                     YGNQWRQASLQGALTDPALADRKPLWQYAEKLDDTYCAGCHAPIAADHYTVNAWPSIA
                     KGMGARTSMSENELDILTRYFQYNAKDITEKQ"
BASE COUNT         2735 a         3182 c         2925 g         3141 t
ORIGIN      
        1 aaataaattt tttatgctat tacgtatatt tgtatctatt tcaatggaat gacaacgtga
       61 atattaatta ccctgctgaa tatgaaattg gagatatcgt ctttacatgt ataggtgctg
      121 ccttatttgg tcaaatatca gctgcatcaa attgctggag taatcacgtc gggatcatta
      181 tcggtcataa cggtgaagac ttcctggttg cagaaagccg ggttcccctt tcaaccatca
      241 ccacgctatc tcgttttatt aaacgttcgt ctaatcaacg ctatgctata aagcgattag
      301 acgctgggct gacagaacga caaaaacaac gaattgttga acaggttccc tcccggctac
      361 gcaaacttta ccacaccggt tttaaatacg aatcttcgcg ccagttctgt tcaaaatttg
      421 tttttgatat ttataaagaa gcgctatgta ttccggtggg tgaaatagag acgtttggag
      481 aattgttaaa tagcaatccg aatgcaaaac tcactttctg gaaattctgg ttcctgggtt
      541 ctattccgtg ggagcgtaaa accgtcacgc cagccagttt gtggcatcat ccgggtttgg
      601 tgttgattca tgcggaggga gtggaaacgc ctcagccgga actgaccgag gcggtataac
      661 ttaacgcagt cgccctctcg ccaggttcag ccgcgattcg ctcatctgca tcgcattctg
      721 actaacgtgg cagtgggtga tagcaatcgc cagcgcatcg gcggcatccg cctgtggatt
      781 agcgggcagt ttcagcaagg tgcggaccat atgctgcacc tggctttttt cggcactgcc
      841 aatacctacc accgtttgct ttacctgacg tgccgcgtat tcaaatactg gcaactcctg
      901 attcaccgcc gccacaatcg ccacgccgcg cgcctggccc agtttcaggg ctgagtcagc
      961 gttctttgcc ataaagactt gttcaatggc gaaataatca ggctggaact gggtgatgat
     1021 ttccgtcacg cccgcataga tgagtttcag acgagacggt aaatcatcca ctttggtgcg
     1081 gatgcatccg ctacccaggt aggacagttg cctacctacc tggcggatga cgccgtagcc
     1141 ggtcacgcgc gaacccggat caatgccgag aataatagcc atcacgcgtc tccgttttgc
     1201 tgtttagcag gcctcatcag agagtcgctg cgacctcatc agagatttca ccgttatggt
     1261 aaacttcctg cacgtcgtcg caatcttcca gcatatcgat cagacgcatc agtttcggtg
     1321 cggtttctgc atccatatca gctttggtag acgggatcat ggaaacttcc gcgctgtctg
     1381 ctttcagacc tgccgcttcc agagcgtcgc gcactttacc catttcttcc catgcagtgt
     1441 agacatcaat cgcgccgtca tcataggtca caacgtcttc agcacctgct tccagtgctg
     1501 cttccatgat ggtgtcttca tcgcctttct cgaaggagat cacgcctttt ttgctgaaca
     1561 gataggcaac ggaaccatca gtaccgaggt taccgccaca tttgctaaat gcatgacgca
     1621 cttcagcaac ggtacggttg cggttgtcag acagacattc aatcatgatt gccgtgccgc
     1681 caggaccgta accttcgtag atgatggttt ccatgtttgc atcatcatca ccgcccacac
     1741 cacgtgcaat tgcgcggttc agtgtgtcac gggtcatgtt gttagacagt gctttatcca
     1801 ccgccgcacg cagacgcggg ttagcgtccg gatcgccacc gcccagctta gccgcggtta
     1861 ccagctcacg aatgatttta gtgaagattt taccgcgctt agcatcctgc gcagctttac
     1921 gatgtctggt gttggcccat ttactatgac ctgccataaa aatatctcca gatagccctg
     1981 cctgttcagg cagcgttaat tacaaactgt tcaatcgcct gccggttgct ccaggactta
     2041 gtgagcgccg ccgcagcagg cgcatcaagc cacttgtaag ccagatgttc agtgaaaacg
     2101 atctgccgct cgtgcggaag cgcaagacag aaccatgatt ccgtattacg cgtcacgccc
     2161 ggcgcatagc gatgacgtaa atgtgaaaaa atttcaaact ctaccgtgcg ctgacagtca
     2221 attaaggtca gttgttcagc gacaacatca atggtgacct cttcctttac ttcgcgcatg
     2281 gcagcttgcg gcgcggtttc accctcttcc acgctgccgg ttaccgactg ccagaaatcg
     2341 ggatcgtcac gccgctgcaa catcagcacc cgtttcgtat cttgtgcgta gatgaccact
     2401 aagatcgaaa cgggacgctt atacacttta tccttcacgc tgcctcttcg ttgactgcct
     2461 tcgctcatcc cattcacata gttatctatg ctcatgggag ttcactcagt tgccgcctcg
     2521 atgcaacgcg aatgatttcg tgtatttgag tcatatcagt tattctcagc cttcttcaca
     2581 acctgaatgc tcagctcagc cagtgcagtc gggttagcaa agctcggtgc ttcagtcatc
     2641 agacacgctg ccgccgtggt tttcgggaag gcgataacgt cacggatatt gtcggtgccg
     2701 gtcagcagca tggtcagacg gtcaagaccg aatgccagac ctgcgtgcgg cggagtaccg
     2761 tatttcagag cgtcgagcag gaagccgaat ttctcgcgct gttcctcttc gttgataccc
     2821 agaataccaa acaccgtctg ctgcatatca ccattatgga tacgtactga accaccgccc
     2881 acttcgtaac cattgatgac catatcgtaa gcgttcgcca ccgcattttc cggtgcagct
     2941 ttcagttctg cagccgtcat atctttcggt gaggtgaacg gatggtgcat tgccgtcagg
     3001 ccgccttcac cgtcgtcttc aaacatcggg aagtcgataa cccacagcgg tgcccatttg
     3061 ctttcgtcgg tcagaccaag gtctttaccc actttcaggc gcagtgcacc catcgcgtcg
     3121 gcaacaattt tcttgttgtc ggcaccgaag aaaatcatat cgccatcttg cgcggcagta
     3181 cgatccagga tgtcttcgat gatttctgca ttaaggaact tcgctaccgg gctgttgata
     3241 ccttccagac ctttcgcgcg ttcgttaact ttgatgtaag ccagaccttt cgcgccgtag
     3301 attttaacga agttaccgta ttcgtcgatc tgcttacggg tcagcgatgc gccgcccgga
     3361 acgcgcagag ccgctacgcg acctttcgga tcgttcgccg gacctgcaaa tacagcaaac
     3421 tcaacagatt tcagcagatc agcaacgtca gtcagttcca tcgggttacg cagatccggt
     3481 ttatcagaac cataacggcg ttctgcttcc gcaaaggtca ttaccgggaa atcgcccaga
     3541 tccacaccct tcacttccag ccacagatga cgcaccagcg cttccatcac ttcacgcact
     3601 tgcggcgcgg tcatgaaaga agtttccaca tcgatctgag taaattcagg ctgacggtca
     3661 gcacgcaggt cttcgtcacg gaagcattta acgatctgat agtaacggtc aaaaccggac
     3721 atcatcagca gctgtttgaa caactgcggg gattgcggca gtgcgtagaa tttacctttg
     3781 tgcacacgag aaggcaccag gtagtcacgc gcgccttccg gcgtggcttt ggtcagcatc
     3841 ggagtttcga tgtcgaggaa gccgtggtca tccataaaac ggcgcaccag gctggtgatt
     3901 ttagcgcggg ttttcaggcg ctgagccatt tccggacgac gcaggtcgag gtagcggtat
     3961 ttcagacgcg cttcttcggt gttgacgtgg ttagagtcaa gcggcagaac atctgcgcgg
     4021 ttgatgatag tcagcgagga cgccagcact tcgatttcgc cggtcgccat atcgcggtta
     4081 atattttttt cgtcacgcgc acgtacggtg cccgtgacct gaatgcagaa ctcattacgc
     4141 agttcagagg ccagctttaa cgcgtccgca cgatccggat cgaaaaatac ctgcacgata
     4201 ccttcgcggt cgcgcatatc gatgaagatc aggctaccaa gatcacgacg acggttgacc
     4261 caaccacaca gagtcacctg ctgccccacg tgggacaaac ggagctgtcc acaatattct
     4321 gtacgcatga gatatccctt aacttagctg ccggcggatg ccccctgctg cgcaggtgac
     4381 caagtcgcag cgttagctgt atgtcacaac tgaatgaaaa aaggcggcta ttatactgga
     4441 aattctgccg caccgtaaga gcctggcccg cgctggaacg cctcgttacc actttatatc
     4501 gggcctgaaa tcagactcta cgccagtttg ctataaaggt gttgcccgaa ctcataaaaa
     4561 ttaacaaaat ttgtcgttcc gccatcggct aatcgcatta aggtgtgagg cacgattttg
     4621 ttttttcagg agtcattatg cttgaactta atgctaaaac cactgcgctg gtggtgatcg
     4681 atttacaaga aggcatctta ccttttgccg gtggtccaca tactgccgat gaggtagtta
     4741 atcgcgccgg gaagctggcg gcgaaatttc gcgccagcgg tcagcccgtg tttctggtgc
     4801 gcgttggctg gtctgccgat tacgctgaag cattaaaaca gccggtcgat gcgccctcac
     4861 cggctaaagt gttgcccgaa aattggtggc aacatcctgc tgcattaggt gcaaccgaca
     4921 gcgatatcga aatcatcaaa cgtcaatggg gtgcgtttta cggtacggat ctggagttgc
     4981 aattacgccg ccgaggtatc gatacaatag tgttatgtgg gatctcgacc aatatcggtg
     5041 ttgaatccac cgcccgcaat gcctgggaac ttggctttaa tctggtgatt gccgaagacg
     5101 cctgtagtgc cgccagcgcc gagcagcaca ataacagtat caaccatatc tacccgcgca
     5161 tcgcccgtgt gcgtagcgtg gaagagatcc tcaacgcgtt atgatttaca tcggtctacc
     5221 gcaatggtcg catcctaaat gggtgcggtt ggggatcacc agccttgaag agtatgcccg
     5281 ccactttaac tgcgtggagg gcaacaccac gctttacgcc ctgccgaaac ccgaggttgt
     5341 cctgcgctgg cgtgagcaga ccacagatga cttccgcttc tgttttaagt ttccggcgac
     5401 catttcgcat caggcagcat tacggcattg cgatgattta gtgactgaat ttttgacccg
     5461 catgtcaccg ttggctccgc gcattgggca atactggctg caactgcctg ccacattcgg
     5521 cccacgggag ctgcctgcgc tttggcattt tctcgattct cttcctggcg aatttaatta
     5581 tggcgtggaa gtccgccatc cacagttttt cgccaaagga gaagaggaac aaacgcttaa
     5641 tcgcggttta catcagcgcg gcgttaatcg ggtgatttta gacagccgcc cggttcatgc
     5701 agcacgtcca cacagtgaag ctattcgcga cgctcaacga aaaaaaccta aagttccggt
     5761 acatgctgta ctgacggcga caaatccgct gatccgtttt atcggtagtg atgatatgac
     5821 gcaaaaccgg gaattatttc aggtctggtt acaaaaatta gcgcagtggc atcagaccac
     5881 tacgccttat ctttttttac atacgccaga cattgcccag gcaccggaac tggtacatac
     5941 cctgtgggaa gacttacgta aaacgcttcc agagatcgga gcagttccgg ctattccaca
     6001 gcaatcttct cttttctgaa tttgccacct atcatagaca ggtgccatcg gccattttaa
     6061 agggagtttg tatggtaagc gcgctgtacg ccgttttaag tgcgttgtta ttaatgaagt
     6121 tctcttttga tgtcgttcgc ctgcgaatgc agtaccgcgt tgcctatggc gacggcggtt
     6181 ttagcgaact gcaaagcgct attcgcattc atggtaacgc ggtggaatat attcccatcg
     6241 cgattgtgct gatgctgttt atggaaatga atggcgcaga aacctggatg gtgcatattt
     6301 gcggcatcgt tttgcttgct ggtcgtctga tgcattatta cggttttcat caccgtctgt
     6361 tccgctggcg acgttccggc atgagcgcca cctggtgtgc gctgttgctg atggtgctgg
     6421 cgaatctttg gtatatgccc tgggagttgg ttttctccct gcgttagcgc acaatacgcc
     6481 actttctttt tcccggattt ttacgttatg tctcaccgcg acacgctatt ttctgcccct
     6541 atcgccagac tgggcgactg gacctttgat gaacgggtag ctgaagtctt cccggatatg
     6601 atccagcgtt ccgtacccgg ctattccaat attatttcca tgattggtat gttagccgag
     6661 cgcttcgttc aacctggtac gcaggtttac gatctgggtt gttctctggg cgcggcgacg
     6721 ctctcggtgc gtcgcaacat tcatcatgat aattgcaaaa ttattgccat cgacaactcc
     6781 ccggcgatga ttgaacgctg ccgtcgtcat attgacgcct ataaagcccc tacgccagta
     6841 gacgtcattg aaggtgatat tcgcgatatc gccattgaaa acgcatcgat ggtggtgctg
     6901 aattttaccc tgcaattcct ggaaccttcc gagcgccagg cgttactgga taaaatttat
     6961 caagggctga accccggcgg cgcgctggtg ctttcggaaa aattcagttt cgaagatgcc
     7021 aaagttggtg aactgttgtt caacatgcac cacgacttta aacgtgccaa cggttacagc
     7081 gaactggaga tcagccagaa gcgcagcatg ctggaaaacg tgatgctgac cgattccgtg
     7141 gaaacccata aagcacgcct gcataacgcc ggttttgagc atagtgagct gtggttccag
     7201 tgctttaact ttggttcact ggtggcatta aaagcagagg acgctgcatg atcgactttg
     7261 gtaactttta ttctctgatt gccaaaaatc atctttcaca ctggctcgaa acgctgcccg
     7321 cgcagattgc taactggcag cgcgagcagc agcacgggtt gtttaagcag tggtcaaatg
     7381 cggtggagtt tctacctgaa attaaaccgt atcgtcttga tttattgcat agcgttacgg
     7441 cagaaagcga agagccactg agcgcagggc aaattaaacg cattgaaacg ctgatgcgca
     7501 acctgatgcc gtggcgcaaa gggccgttct cactgtatgg cgtcaacatc gataccgaat
     7561 ggcgttccga ctggaaatgg gatcgtgttc tgccccatct ttctgattta accggacgca
     7621 ccattctgga tgtcggctgc ggcagcggtt atcacatgtg gcgcatgatt ggcgcaggcg
     7681 cgcacctcgc ggtggggatc gaccctacgc aactgtttct gtgccagttt gaagcggtgc
     7741 gtaaactact gggtaatgat cagcgcgcgc atttgttacc gttaggtatt gaacaacttc
     7801 cggcactgaa agcctttgat accgtctttt cgatgggcgt gctttaccat cgccgttcac
     7861 cgctggagca tctatggcag ttgaaagatc aactggtcaa tgaaggtgaa ctggtgctgg
     7921 aaacgctggt tattgatggt gatgagaaca cggtgctggt accaggcgat cgttacgcgc
     7981 aaatgcgtaa tgtctatttc atcccttccg cgctggcgct gaaaaactgg ctgaagaagt
     8041 gtggttttgt agatatccgc attgcggatg tgagcgttac caccacagaa gagcagcgac
     8101 gcaccgaatg gatggttacc gaatcgctgg ccgatttcct cgacccacat gatccgggta
     8161 aaacggtgga aggttatccg gcacctaaac gcgcggtgct gattgcgcgc aagccgtaaa
     8221 ggtctggtat tactgccgga tgcggcgtga acgccttatc cggcctacaa aaccttgcta
     8281 attcaatata ttgcagggac tatgtaggcc tgataagcat agcgcatcag gcagctttac
     8341 gtttgcataa cctcagcgcc cgtttccggg cgctattcac gtcttacgcc tgaacagctg
     8401 gctgatcaaa cgccgttaac ttcggtgcat tgcccgtata tttttcgata tacaccaacg
     8461 ctgagttacc ggcacaggca tttgccagct gcgagctggg gatatccgcc gttaacacgt
     8521 tcgcactgcc gtttttacac aagccatttt ccagatctgg ccatgcacct tcatgcacgc
     8581 ataccacgcc ttttttgatc ccgtcagtca ccaccgcgcc tgtcaaaatc tgaccacgtt
     8641 tgttccagac acgcaccaga tcgccattcg caataccaaa gcgtgcagca tcttcggtgt
     8701 gaatagtgat tggttcacga tcggcgatcg catatttttt acgcagttcc gcatagttaa
     8761 gctgactgtg taaacggtgt gccggatgtg cggtcagaag ctgtaactgc ttctcgtcgg
     8821 cggtaccttt ccattcatca ggagccagcc aggttgggtg tgccgggcaa tccttatagc
     8881 caaatttttc caacgttttt gaatagattt caattttgcc gcttggcgta cccagcgcat
     8941 ttttcaccgg atcggcgcgg aaatcaccat aacgaacgta ctgttcgttc ttctcgctgc
     9001 ggcgcatttc gatcagttta ttttgctgcc agaaggcatt aaacattggc atagtgacgc
     9061 gttgcgcacg ggcacctttc tgagcggcat catagaaaaa tttcagccac gccatttcat
     9121 ctttaccttc ggtatagatc tcttttccgc caggtttgag taattccgca agatcggcaa
     9181 acacgtcaaa atcgttacgc gcttcaaatt gcggagcaac agcctgcttc atcggcacaa
     9241 tatgctggtt gctgtaatca ccggtcatcg tcaagtcatt gcgctcaaac gatgtggtga
     9301 tcggtaatac gatatctgcg tgtttggctg ctgcggtcca gtagcattca gaaacgacga
     9361 tcatctccgg tttctgccat gctttaatca gacgattagt atcctggtga tgggtaaagt
     9421 taccgccacc cgcccaccag atcattttga tattcggata cgtttgttct ttaccgttat
     9481 gctgatattt gccgccagga ttttccagcg catcgacgat acgggcaaca ggaatcgccg
     9541 tcattccgcc atcatcagcg gcctcgctgg catgtccggc aatcgccgca gacatttccg
     9601 gcagcacgcc gccaacacgc gtcgggttgc caccgttgga gtaatgataa gagaaaccaa
     9661 aaccgccgcc cggtgtacca atctgcccta acatcgccgc cagcgtcacc agcatccagt
     9721 gtttctgttc accatattgc tggcgctgaa ttccccagcc tgccatcagc attgtgcgat
     9781 tcgccgccat cagttcagcg agtttgacta tctgcgcttc cggtacgcca gtaatttccg
     9841 ccgcccagac cgcgctcttc ggcgtattat cgctcttacc tgtcagatac tcttcaaact
     9901 gcggataccc ggtagtgtat ttttcaagga acactttatc gtgtttgcct tgtgtcatca
     9961 gggtatgcgc aatccctaac atcagtgcca cgtcggtgcc catattcggc gcgatccagg
    10021 tggcattatc gtcaaagaat tcgatggttt cggagcggat aggatcaatg gcaatcactg
    10081 gtttgccaga ttttttcagc tgatggaagt attccagccc ttgctcatcg gtactgctcc
    10141 aggcaatttt taaggtattc agcgggttca ttccccacag caccacaacc tggctgtttt
    10201 ccagaatcag cggccaggag gtctgctgtt catacacctc tacagaaccg accacatgcg
    10261 gcatgatcac ctgtgctgcc ccggttgaat aatcgccgct atgcccggaa taaccgcccg
    10321 ccaggttcat ataacgttgc agtaaggttt gcgctttatg caacacgcca gaagagcgcc
    10381 agccgtaaga tccggcaaaa atggccgatg gtccgttagc tttacgaata cgatcatgtt
    10441 gctcatgaat cagttttaat gcctgttccc agctcacctg tacataggta tcttcgccac
    10501 gacctttcgc cggttgcagt ggattatcga gatagctttt tctcaccatc ggatgctgaa
    10561 tacgcgccgt ggtgtgtacc tgatccgccg ccgtagactg taaggaattc ggtatggttt
    10621 tcgccagcgc gcctgttgaa gaaacaatct tgccgtcctt cacttctacg ttcatcgctc
    10681 cccaacgtcc cgcggtgagg attttaccgc ccttctcttc tgcccatgcg gggagcggtg
    10741 ctgccgatgt caccaccagc gctccagcgg caataccgct gtgtttaata aattcacgtc
    10801 ttgttaatgt cataacttcc tccctgatca acgaggatca ctgtttctcg gtaatatctt
    10861 tggcgttgta ctggaaatac cgcgttaaaa tgtccagttc gttttcgctc atgctggttc
    10921 gtgcccccat tcctttggca atggacggcc acgcattgac ggtgtaatgg tcggcggcaa
    10981 taggggcatg acaaccagcg caataggtat cgtcaagttt ttcagcgtat tgccatagcg
    11041 gtttacggtc cgctaatgcg ggatcggtaa gcgcaccctg taaagacgcc tgacgccatt
    11101 gattgccgta ttcgtcagcc tgccattccc cgtttacagt gagcgccttg ataccttctt
    11161 cacttaatgt ggctagcgcc agccgttgac ctgccgccag gtagagcgtg ttttcactgc
    11221 cctgcatttg ataaccctgc aacagaacga tcggctgttt gccactggca tcaacgacgg
    11281 tgagatcggt tccaggattc acggtagcca gctcgcctat gtgagaagtt ttgaaaggat
    11341 aaatatgtgc gccattagta actgaagtag cggcctgact ttccagctca tgcgccgcgt
    11401 tgtcatccat ttttatttct ggcggaaaat gggcaatgcc tttatgacaa tcgatacagg
    11461 tttcgctgtc cttttgtgct ttgttatgca ttttctgcgc agattcactt tgcgaggcaa
    11521 tatccatggc atcaaaagaa tggcaactac ggcacgttgc agagtcagtg gcttttaatt
    11581 ctttccatac tgtttcggcc atttcctggc gatgagcttc gaacttatcg tcactgtcta
    11641 ttttgccgct aacaaattca tgataaatat ctttagatgc ctttaattta gcaaataaat
    11701 aatccatccc tgactttgga atatggcaat cggcacattc cgcacgtatc cctttctggt
    11761 tcgaaaagtg gacagttccc tgatattcct caaaaggttt actcatcgag tggcaggaaa
    11821 ggcaaaatgc tgtatccgac gttttatgta aggctttttg cgccagcaat aacccgccgc
    11881 caccaaccac aaccgctatc agcaaaaaca ataacccaat gcgttttttc cctcgcatag
    11941 attcctctaa ttaaattact ggacaccgaa atcattgtat aat
//
LOCUS       DAPOAV010000110        11800 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.110, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000110 DAPOAV010000000
VERSION     DAPOAV010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11800
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.110"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..945
                     /locus_tag="RN951_003808"
     CDS             <1..945
                     /locus_tag="RN951_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 9 protein"
                     /protein_id="HDX2528742.1"
                     /translation="QIGDAMAIFPVIRALELHKIKHLLIVTSTINLEVFNVLKLEQTK
                     LTLVTMTMQDHATLKEIKDLAKNITQQYGTPDLCIEAMRKKNLKTMLFISQLKAKTNF
                     QVVGLTMKCYSPVCKNASRMDQNLRAPVPMTWAFMIREAGFPAVRPIYELPLSEDVLD
                     EVREEMRSLGSYIALNLEGSSQERTFSLSIAENLIAKIQSETDIPIVIAHGPKGEDKA
                     RVLVDCYNNVYRLSLSPSIKRSAAIIKDAYIAITHDTSILHMASAYNTPVVAIYADYK
                     TRWPAMADVSESVVVGQKIDNISLDEFAKALKSVLARI"
     gene            complement(1207..9189)
                     /locus_tag="RN951_003809"
                     /pseudo
     CDS             complement(1207..9189)
                     /locus_tag="RN951_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010904796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
     gene            complement(9501..9576)
                     /locus_tag="RN951_003810"
     tRNA            complement(9501..9576)
                     /locus_tag="RN951_003810"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9541..9543),aa:Asn,seq:gtt)
     gene            complement(9677..10474)
                     /gene="mtfA"
                     /locus_tag="RN951_003811"
     CDS             complement(9677..10474)
                     /gene="mtfA"
                     /locus_tag="RN951_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgsA anti-repressor MtfA"
                     /protein_id="HDX2528743.1"
                     /translation="MIKWPWKVQESAHQTALPWQEALSIPLLTCLTEQEQSKLVTLAE
                     RFLQQKRLVPLQGFELDSLRTCRIALLFCLPVLELGLEWLDGFHEVLIYPAPFVVDDE
                     WEDDIGLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGD
                     RASGVPFIPLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSE
                     YFFSAPELFAPRFPSLWQRFCQFYQQDPLQRLHHANNTDSFSATNVH"
     gene            10568..10657
                     /locus_tag="RN951_003812"
     tRNA            10568..10657
                     /locus_tag="RN951_003812"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10602..10604,aa:Ser,seq:cga)
     gene            complement(11227..11757)
                     /locus_tag="RN951_003813"
     CDS             complement(11227..11757)
                     /locus_tag="RN951_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416483.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
                     /protein_id="HDX2528744.1"
                     /translation="MNRFSKTQIYLHWITLLFVAITYAAMELRGWFPKGSSTYLLMRE
                     THYNAGIFVWVLMFSRLIIKHRYSDPSIVPPPPAWQMKAASLMHIMLYITFLALPLLG
                     IALMAYSGKSWSFLGFNVSPFVTPNSEIKALIKNIHETWANIGYFLIAAHAGAALFHH
                     YIQKDNTLLRMMPRRK"
BASE COUNT         2880 a         2795 c         2830 g         3295 t
ORIGIN      
        1 cagattggcg atgctatggc catctttcct gttattcggg cgcttgaatt gcataaaatt
       61 aagcatctat taattgttac gtcgacaatt aatttagaag tctttaatgt gctcaaactt
      121 gaacagacta aattaacatt agtcacaatg actatgcagg atcacgcaac attaaaagaa
      181 ataaaagatt tagcgaagaa cataacacag caatacggta cgccggatct ttgtatagag
      241 gcgatgcgta aaaagaacct gaaaacgatg ttatttatca gtcagttgaa agcaaaaacg
      301 aattttcagg ttgttggttt aaccatgaag tgctattccc ctgtgtgtaa gaacgcgtcc
      361 cggatggatc agaatctccg ggctcccgta cccatgacat gggcatttat gattcgtgag
      421 gcgggttttc cagcagtcag gccaatatat gaattgccac taagtgagga tgtactcgat
      481 gaggtgcgcg aggaaatgcg atcgttagga tcttacattg cgcttaattt agaaggtagc
      541 tcgcaggaac gtacattttc actatcgatt gcagaaaatc taatagcaaa aattcaaagt
      601 gaaacagata taccaatagt gatcgctcat ggaccaaaag gggaagataa agccagggta
      661 ttagtggatt gttataataa tgtctaccgt ttatccttat caccctcgat taaacgttca
      721 gcagcaatca taaaagatgc ttatatcgca ataactcatg acacttcaat attacatatg
      781 gcaagtgcct ataatacccc cgttgttgca atttatgctg attacaaaac gcgatggccc
      841 gcaatggccg atgtttcgga gtcagtcgtc gttgggcaaa aaattgacaa tataagtctg
      901 gatgaattcg caaaggcatt aaaaagtgtt ttggcgagaa tatgagacag tacttatgca
      961 tagtaatgcc gatctgttat gaacggtggt gtcatcaata ctctgaggct ggtcaatcat
     1021 cacagaaaac cagcctttgg atcaaagctg tactcaccgg atacgatcat agtcacatcg
     1081 aacgcgattc ttgcggtgca gcagttttat ttattcattt tctgtgagag aagggcaagc
     1141 tctatagagg gaatgtaaaa aagagtgctc cgaatggagc actctttaag aaattataac
     1201 ggaaaatcac aggtttttat aacatgtcgc ataagcaaac ccaagctttt caaatacgct
     1261 ttgatcacct gttgccaggg aaactacgta ttgttcgctt gagtttgcgg gactagatga
     1321 ccaatacata tttgatcgaa aaccagcttc agtcgtgtaa tgccccatat ctccccattc
     1381 actgtacagt gacccgatgc ctcgggaacg actatggttt aaatggtctg cacggggaag
     1441 tgtgtagcca ttgctactgc aaaaattttc agcaaggctg tatatcatga aagcatcgcc
     1501 ggagttcacc caccaactct tcacacggat ttcgtataca tagctagggc ctcctgattt
     1561 tggcgtcgcc gtaatccttt cccaattgct gccgacattt ttaaatgtca ctttaccgat
     1621 agcatcaaca tcgacccagg aggcagagct tgaaaactca taatcagccg ccgtttttcc
     1681 tggggcaaag ttgtcattat tcaactgata atacgccccg gtgaacccct gcgaagggaa
     1741 tgtagttgtc ggtaggtcag taccattgac tgatactgta ccgctcatta ttttgtcttc
     1801 tgcgcgagtg aattgtattg tggtactcag accagcttga tgaacaccat tcaatacagg
     1861 gatcagcgtt gcgataccct ctccgccgcc tgtaatggtg gctttataat caccgttgat
     1921 attttgactg taatcaattg cgctaatttt catatagggc acgttagtac ctgattgcac
     1981 aaattccatc ccttcagaaa ctttgatcgg attgcctgat atatcgtgca aaacaagatg
     2041 tagctcagca ctatcggtaa agtccccttt cagtgaggac cgattgttct taaggacgga
     2101 ctgcgaggcg tctgccgggc ctgccaccag cgttatatct actgtttgca ttccaccagc
     2161 ggtcgtgact gcgcttaccg tgacgctacc tgtcatcgct cctttcacgc ttgttgtcgc
     2221 gattccgttt tgatcggtca ccgctgttaa tgacgttaat gtggcagagc cgctttttaa
     2281 ggcgaagtac acagtgagac cttcgatcag gttaccactg ccatcctcaa ccgttgcctt
     2341 taaggtactt aaatcactgt tggtggcggc gatagtcgat ggatcagcga taaagctagc
     2401 aacatgtgcg gtgcttgagt tgccagtgac tttcacggtt gtctgtgtct gtattgttac
     2461 gccgttatgg aacgatgcag tcaccgtata tgtaccgact ttattgctgg tcagaacgac
     2521 cggagcctga cctgaagagt tagttctcac ttttccgcca cttaacgtcg ccccttctgg
     2581 cgttacgcta aagttgatga cctgaccctc cactggagtg ccatttgcag aggttagcgt
     2641 tgccgtcaga gtagtgcctg taggggcata gacaccgata agcggactgg acgccgtgag
     2701 tgtcagtttt tcatcaatag cctccagttg tttctcaagt gaggctccat tcgccaggga
     2761 tgctttcacc atatacgaac cgtttctttc gggcgtcatg gagacctcgg ctataccatg
     2821 cgtatcagta gagacaatat tttggctgat ggtcatgtgc tctggtggct ctgcactgaa
     2881 tgtcacgggt tgatgcgcaa ccgggttgcc aaactggtcg ttaacgtgag ctttaactgc
     2941 tacgtcttgt gcgaccatta cctgaccttc cggtatctcc agactggtaa tcgtcgcaga
     3001 attaacatct gcactggcat tcagtaatcg cgagatgact tcagtaggtt tatctgccag
     3061 agaggctgaa actgttttca gtccgacctc ggtgcttgtc acaagaattt cagcgaaacc
     3121 ccgatcatcc gtttcaacgc tggtgctgct tagcgtgacg gaggttccgc ggaaactaac
     3181 ttttatgcct tctaccgggt tgccgttagc gtcagtgacg cttgcagtca tggtcgcgcc
     3241 ctcggtcgtg ctgacgacga atgagtatac agaggttaag gaggctagtt ttgcggtacc
     3301 agcatcggca atcaaagtca cctgtttcgt atcactgaca ccataattgt tcacgctaac
     3361 tgtcacgggg taggagccgg attttgtacc gctcagtgta acttcagcct tgccgttgat
     3421 gtcagtaatg gcggaaccgc cttgtccgag agtaaagctt gcgctcacat ctgccggtag
     3481 cgtgaatgtc accgcctcat tggctaacgg gttgccgttt ccatcagtca ctgttgcctg
     3541 cagcctggtc atcccgacgt tattagcgat aaagttgtcc tcggtaacgt taagattaac
     3601 ctgcgctgtg agcgtatccg caataaaatt caccaccaac tgctcactct taccgccagc
     3661 catcgatgct gtaacagtat gagcgcctgc ttttgtacct ttcagcgtga ctttcgcttt
     3721 gccttcagta tcagtaaccg ctttaccgcc atcgctcagc gtgaagttcg ccttcacatc
     3781 ttccggcaga gtaaatgtta cctcagtgtt ggctatcgca ttgccctctg tatcagcgac
     3841 tgttgctgtt agtgtcgtga gatcgttatt gtcggcaatc accggatcct tcgaggctgc
     3901 cagcgtgatt tcagcattcg cgacgttcgg cacataggtc actgtttgtt gcatcgaatc
     3961 gccattttcg agggttgccg tcaattgata aaccccggct tttgtagcgg taaagcttgc
     4021 gtaaaaattg ccgtcgtggt tggtagtata tatagcgtta ttactggggg tcacgccttc
     4081 acttggtgaa acgctgaggg ttacctcctg ctgggggaca ccgttgccgt aattattctt
     4141 cacctcaata tacagactgg ttgtctcgcc tgcggagact gtatcaaaaa gtgcctgtag
     4201 caaggtgaga tgtgccgtag acgcatcagc gttgacatta attgatgtgc taagcgtgga
     4261 gctaccattt tccagactgg cctcaacggt atccggtctc gctcctgatt ctatcgagga
     4321 gcgggtattg gtataagtga cggtagcctt accctgttcg ttcgtcacgg cttgaccgcc
     4381 gttcgtcatt tcggctgtcg ctgcgttgct ggtgaagttc acagtcacac ctttcaccgg
     4441 aaagccatta ttatcaacga ctgtggcggt gatgacgctg ccggagctgt tctgcggggt
     4501 accggcgatt atgctgtctg ggacaggcgt caactcgata atttttgccg ccgctgtgtc
     4561 gccaataaaa tgcacagttt tgttgtcgct ggcaccatta ttagccagtg atgcagtaac
     4621 cgtcttctca ccaaaggcaa cgcctgcgag agtggcctgc gcgatgccag actcgttggt
     4681 attacttact cccgggggca gggtgagtcc tgaagaggct gagctgaatg ttaccggaag
     4741 attattcacc tcattgtcga actgatcttt aaccgttgca gttagcgttg cgctatcgac
     4801 gccattacct gtgatctcat cttttgatat ctgcagaaca acctgagccg aggctttgtc
     4861 cgccacaaat gttaccggct gcgaatcact ggtattgtta ttacccagcg ttgcggtaac
     4921 cgtatgcgtg cccgcttttt tacctttcag cgtgacatgc gcttccccat tggcctgggt
     4981 gatggcaata ccgttatttt caagggtaaa gtttgccgca acgtcctgtg gcatggtgaa
     5041 gttgaccgtt atccccgcca ccggatgatt cgacggatct ttcaccatcg ccgtaagctg
     5101 cacgctgtca ctgttattcg tcaccacctg ttgagcaggg atgttcaggg tgacctgcgc
     5161 gttgctggca tcgggcgcaa tattgactgt cgtcgtatag ccattgccgt taagcagcgt
     5221 ggcttcgact gtatgaacac ccaaaaccgt gcccttaagg gtaacttcag caacaccact
     5281 gtcgttagta ttgcttgtgc tctgactaag ttgagtatct gccgggttgg tactgaaggt
     5341 gaccggtaga tcttttacta cgttatcaaa aggatctttc actgttgccg tcagagtcgt
     5401 ctcatccacg ccattcccaa tgatttccgc tttcgatgtt tgcagaacga caaccgcgct
     5461 gtccttatcc gccacgaagg tgactggttg cgcatcgctg gcattattgt tacccagcgt
     5521 tgcggtaacc gtatgcgtgc ccgctttttt gcctttgagg gtgacatgcg cttcgccatt
     5581 ggcctgagtg atggcaatac cgttattttc aagggtaaag tttgccgcca cgtcctgtgg
     5641 tatggtgaag ttcaccgtta ttcccgccac cggatgattc gacggatctt tcaccgtcgc
     5701 cgtcagctgc acgctgtcgc tgttattcgt caccacctgt tgtgcagtga tgttcagggt
     5761 gacctgcgcg ttgctggcat cgggcgcaat attgactatc ttcgtatctc tgttgccgtt
     5821 aagcagtatg gcttcggctg tatgaacacc caaaaccgtg cccttaaggg taacttcagt
     5881 aataccgttc tcattagtat tacgcgcgtt cagactcagt tgcgtgtctg cgggggaggt
     5941 gcggaagact actgatagat ttttaaccac gttatcaaaa ggatctttca ctgttgctgt
     6001 cagggtcgtc tcatccacac cattcccaat gatttccgct ttcgatgttt gtagaacgac
     6061 aaccgctctg tctttatccg ccacaaacgt cattggctgt gcatcgctga cattgctgtt
     6121 agccagacga gccgtgatca tatgcgtgcc cgctaacgtg ccggtcaggg aggcgattgc
     6181 aaccccgtta ctatccgtca tgccttttcc gccgttgcta atcgagaacc gacttgcgac
     6241 gtcgtttggc acagagaagg tgatttcttt atcttttagt gggttgccat ttttatcctg
     6301 caaggttgca gtcatatgtt gcggagctgt gttggtgacg gtgatatcac ctgaaggcac
     6361 actgagggtc agggctgcag tactttgatc accgataaaa ttcacctgtt gattagcctg
     6421 agaaccagag ctcacagagg ccataaccgt ataatcacca tttttcaaac tggtcagcgt
     6481 agctgtggcg atcccgtcgt ggctattcac ttcggtttgg ctcagtttcg ctgctgctga
     6541 attaacattg aaggtgacct tgacgtcatt gagcaggttg ccttttgcat cccgaactgt
     6601 cgcggtcatt gtggcgctgt cattgccgtc agcgaccact tcatttttcg acttctgcag
     6661 atcaacctgt gcggtactcg agtcgccgac aaaactgacg attaacgttt gtttcacgcc
     6721 attttcaagg gtgacttcaa ccgtgttgtc ttcctgctta ctacttttca gatcaatagt
     6781 cgccagacca ttaacatccg tttttgcggt gttttgattg ttaaaggaag ttgccgatcc
     6841 gcttaatacc gcaaacgtga cggtatgatc attgattggg ttgcttcctt catcagcgac
     6901 attgaccgag acggtgtttg ctgcattctc attggcgagc acaccattat tgctggcaga
     6961 taatgtcgca attttcgctg actgcgggtt ggcgtcgatg ataaatccag cggtatgcaa
     7021 atcttcattc cagttttgca ttaatagctt cgcagtaagc ccactgcctt tggtataggc
     7081 ggtataggtt gccttataga cgccatctgc ggtttctttc cagtctgtag tgacaccagg
     7141 tttcacattg tcgatgctga ctgcggtatt cagttgctgt ttttgctcct taacaggttt
     7201 gtcattttca tctctcagtt ctaccgttac ctcgatagga ttgccggaga gataacggtc
     7261 cttatcaatc ttaattgacg agtgagtccg ggatgacgaa acagaaatga tattcaccac
     7321 ggcgggggct ttagccgcat ccacaccgtt cagctgtggc ataagcgtca gcgtgccaga
     7381 catcgcacct gtggtcagga tctgggtata gcttccgtca ccattatctt tccagtcaga
     7441 aagggtgatg tcctgaacac cttcgtgacg cgtcgagagc accagcccga taacaggatt
     7501 acctgctgca tcatgcgcaa taaaagtcag tgtggcggtt gaatgggaat ccgcgctcaa
     7561 cgtctgggta cttaacgata ccgaggaatc tttctggctt aacgtaggtg cctgaacgac
     7621 taccatgctc tgttcacgat tcgaacaaat tgcctttgac atcttcagcg gtgacttcaa
     7681 tcggccaggt gttatcggtt tctggcgtac tggtgaaccg gtacgccggc agggtaacca
     7741 gaatatcttt acccgttgta accactttac caccggcagc ttccagagcg gtggcttcga
     7801 cgttatagcc tttcagggca tatttggttt gtagcgacga aaccagtgat ttcacttctc
     7861 ctgacttccc tgtcacgggg tctgtcaggg acaggcgaac cagttctttt ttgcgatatt
     7921 ccagaacgat gttgttgttg cgatccacca gatcataacg gctgcttgca aggctacgcc
     7981 gtgcagcgac ttcattcggg tcaagctgtt tctgcattgc gctgccaggt tgccaggtaa
     8041 aatcgacggc aaaacgggtg tcattttcgc cctgtttacc ctgacgttgc tccgcgctga
     8101 aggtcatcag cgggaagggg gtatagttaa gtccagcggt tatggcatga ggattacttt
     8161 gccgatcgtc tttatcgaac agggccactt catcgccata atactgttca tagaccagtt
     8221 taccgccaag gtgcggccag gcgggtagcc agccttctgc gcgtacatcc cagccattgg
     8281 ccgggcgtgc ttcataatcg ttgtccagtt caggtgcgct gcgccagttg gtcagtcgca
     8341 aatagccgtt actgcttaat tttagatagt cgcgccagta ctccgcgcca atgccggcgc
     8401 gggagtggta acggctaaga tcgtggtcga aaaagaagtt gatgcccgac atccatgtgg
     8461 gagtgaaatg acgccaacct aagccgttgt taatctgcgt acgctcgtca gtacgatgga
     8521 gagtatgctg actgaaaaag agattatcag gcgtttcata ccacggatgg agaaaatcga
     8581 actgggagtt cttcaggcta aaatcttcat ccacgcccag cgtgattctt gcggtaccga
     8641 agcggcttaa ccagtctgtc attgcgcctg aagcctgaga agaggccatc cacgcgccat
     8701 atttgccgct tgctcgctgt tcatatcctc ggcgagcaga gacccgattt gctgtgaagt
     8761 actggctatc tgttgctcaa ggttgccact gctattaccc ggtggcgggg ttaaattatt
     8821 ttcactaact tgtgccggga catccagttc atcaccctgg cggacattat caaaacctcg
     8881 agcaaacgta cgaaactggt tgagtttgcg taactcagcc accgaaatac cgaaacgttc
     8941 ggcaacgctt tgggccgatt ccagcgctcc aagggtgtag ggcaccgtat tggcatttgc
     9001 aatggcaatt tgtgcaggaa ctggttgttg ggttgcggcg tttaccacac cttgtgctgc
     9061 cgcagccata gggaacacaa gttgagttac caggcagata cccgcagtta agcggcatag
     9121 tttgataccc atcccgcata agatttgtcg gtcatttatt tcttctccac ttctcttctt
     9181 cgtagccatg cttaccttcc ctgaacgagc taacataaat gcgccctttc tagcacagcg
     9241 aaaaaatgta aatcctgata gcaatatgat tgaaaattaa taacttttcg ttaggcagtt
     9301 ttgggtgtga gttgcaagag gggagactac tgaattactc aagttttata atcgagggga
     9361 aaatggtgat gacgccatag caaaacgccc tcaaccataa agttcgaggg cgcttaagat
     9421 gttaaaaacc cgctatccgt taaaaaacaa tgttcaacta aggttagtga cattgcacta
     9481 agaagcgaat ttttagaatt tggctcctct gactggactc gaaccagtga catacggatt
     9541 aacagtccgc cgttctaccg actgaactac agaggaatcg tgtgaacggg gcgcatatta
     9601 cttagcggta ccttgtctgt caacactaaa tttcataagt catttcaatt ggttaattaa
     9661 tctgcaaagt tgttaattaa tgaacattcg tcgccgaaaa cgagtctgta ttattagcgt
     9721 gatgcagtct ctgcaaagga tcttgttgat aaaattggca gaaacgttgc cacaatgaag
     9781 ggaaacgagg agcaaaaagt tctggggcgc taaagaaata ttcagaaagt acggcaaaac
     9841 attcagcagg atcactggca gcataagcat caatgctcgc cgcattctcg ccaaccaatt
     9901 cgatttcttc ctgaatgttg ttcattgcag catgaagatc gtgttcccag ccagcaacct
     9961 cacgcaacgg aataaaggga actccgctgg cgcgatcgcc gttacgggtg tccagcttat
    10021 gagcgacttc atgaataatc aggttaaaac cagaagcatc aaaagaatct tgtatatcca
    10081 accagttcaa aacgataggc ccttgctgcc agctctgacc tgactgaaca atacgttggt
    10141 tatgcaccag accgatatcg tcttcccatt catcatcgac cacaaatggc gcaggataaa
    10201 ttaagacttc atgaaaacca tccagccatt ccagtcctaa ttccagaacg ggtaggcaaa
    10261 atagaagtgc tatccggcag gttcttaatg aatccagttc aaagccctgt aaaggaacaa
    10321 gccgcttttg ctgtaaaaaa cgttcggcaa gagtgactaa tttgctttgt tcctgttccg
    10381 tcagacacgt taaaaggggg atcgatagtg cttcctgcca gggaagggca gtttgatgtg
    10441 ctgattcttg tactttccag ggccacttaa tcatcgtttt gctcgcaaac tcgtcacttg
    10501 aacaaaattg cacggacagg gactgttaaa atgccaaatt tcctggcatc atggcaacca
    10561 tctgaacgga gagatgccgg agcggctgaa cggaccggtc tcgaaaaccg gagtaggggc
    10621 aactctaccg ggggttcaaa tccccctctc tccgccactt tatcaatgac ttatctcccg
    10681 acttcccgcc ttgcttttcc taaacagaac aatcgtagaa tattcttgaa gggttagatc
    10741 gtcactgttt tctgttcgat actgtgacat tcagcacttg attcgctatg gatctgacag
    10801 gaagctttcg agcgaaaatg tgcagttatt cagtcgtttt cttatcgctc accattattc
    10861 ttttagacat tcatcctatg aaactgccgc aaagttggtg gtgggaactg aagttgcgta
    10921 gagaaggggt caataattga gtcaaaaaag gaacgcggcc gtcagattaa agccgcggga
    10981 caaagtccat aatttccaag agttgttgaa tttcgcagct tttttgaaag cctttgtatc
    11041 atactaacaa gtaaaaaagg tttaaatacc aaaattaacc tgtatttttg ataagtctta
    11101 ccattgtacg atttacacag tttctgctcc tccttgttga tagtggaaag ggtgcattgt
    11161 gcacttgcgt aaacatttat gacgcgttga tgtccatggt tcacatttcc ttgtaagggg
    11221 atcgacttat ttgcggcgag gcatcattcg taacagagta ttatctttct gaatgtagtg
    11281 atgaaagagt gctgcgccag cgtgagctgc gattaaaaag tagcctatat ttgcccaggt
    11341 ttcgtgaata ttttttatca gtgctttaat ttcgctgttt ggggtaacaa agggagacac
    11401 attgaaacca aggaaactcc acgattttcc actgtaagcc atcaaagcaa tccccagcag
    11461 aggaagtgca aggaaggtta tataaagcat gatgtgcatt agcgaagccg ctttcatttg
    11521 ccaggcaggt ggcggtggca caatagaagg atcactataa cggtgtttta taatcaggcg
    11581 tgaaaacatt aacacccaaa cgaatatacc cgcattgtaa tgtgtttctc gcatcagcag
    11641 ataagtacta ctacctttag gaaaccagcc acggagttcc atcgcggcat aggttattgc
    11701 aacgaaaagc agcgttatcc aatgtaaata aatttgagtt tttgagaatc ggttcatttt
    11761 tgtagctcct gtgattttca cagtcaagct atcccacgaa
//
LOCUS       DAPOAV010000111        11659 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.111, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000111 DAPOAV010000000
VERSION     DAPOAV010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11659
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.111"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            373..612
                     /locus_tag="RN951_003814"
     CDS             373..612
                     /locus_tag="RN951_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001446914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HDX2528745.1"
                     /translation="MSLNFKWLNWLYNQGFLLPAREHDINDNLLFKWLRLWLIKGRIS
                     RRLPVRNSSGIGVELLPVEMTLDERPYPAFYARLL"
     gene            complement(823..2079)
                     /locus_tag="RN951_003815"
     CDS             complement(823..2079)
                     /locus_tag="RN951_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011815933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDX2528746.1"
                     /translation="MDFFRFLMSDVLSEPAVLVGLIALIGLIAQKKPVTECIKGTVKT
                     IMGFVILGAGAGLVVSSLGDFANIFQHAFGIQGVVPNNEAIVSVAQKSFGKEMAMIMF
                     FAMVINILIARFTPWKFIFLTGHHTLFMSMMVAVILATAGMTGITLIAVGSLVVGVAM
                     VFFPAIAHPYMKKVTGSDDVAIGHFSTLSYVLAGFIGSKFGNKEHSAEDMNVPKSLLF
                     LRDTPVAISFTMSIIFLVTCLFAGADVVKELSGGKNWFMFSIMQSITFAAGVYIILQG
                     VRMVIAEIVPAFKGISDKLVPNARPALDCPVVFPYAPNAVLVGFLSSFAAGLIGMFML
                     YLLNMTVIIPGVVPHFFVGAAAGVFGNATGGRRGAILGAFAQGLLITFLPVFLLPVLG
                     DIGFANTTFSDADFGALGILLGIIVR"
     gene            complement(2092..2379)
                     /locus_tag="RN951_003816"
     CDS             complement(2092..2379)
                     /locus_tag="RN951_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004717867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDX2528747.1"
                     /translation="MKITVVCGNGLGTSLMMEMSIKSILKDLSVSADVDHVDLGSAKG
                     TPSDIYVGTKDIAEQLVAQSVAGKIVALENMIDKKAMRERLSVVLTELGAL"
     gene            complement(2395..2838)
                     /locus_tag="RN951_003817"
     CDS             complement(2395..2838)
                     /locus_tag="RN951_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011192680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDX2528748.1"
                     /translation="MLKNLLNTEVVQVVEQAKDWREAVAISCRPLIENGSIEPRYVDA
                     IYRSHDTIGPYYVVGPGIAMPHARPEEGANKLSLALTLIPSGVNFDADENDPVKLLIV
                     LAATDSTSHIEAISQLAKLFDNEKDIQAILMAKTTQDILSVIARY"
     gene            3109..4140
                     /locus_tag="RN951_003818"
     CDS             3109..4140
                     /locus_tag="RN951_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDX2528749.1"
                     /translation="MEKTRKRRGTGRVTLQEVANFAGVGTMTVSRALRTPEQVSDKLR
                     EKIEQAVEELGYIPNRTAGALASGHSDTVAVLVPSLTDKASSRFMQSLQQVLNKNEFQ
                     LLLGCHEYNQLKEAEILMTLLQGNPAALVIFGSQLADKTHQILEKTNIPTINVVGSPF
                     SPAQITIETAFFEASHKLTEHLLEQGYKNIGFIGAHMDNRLQRQQLNGWHKAMLSHYQ
                     NSDLVITMPDAASLQLGRYALNEILLRQPELDAVICSHEEIALGIMFECQRRLLKIPG
                     NIAVACLDGSDNCDQTHPTLTSIRIDYKKMGIETGKLLIGLLNNNHDESEESRIVQFN
                     YQIELRQST"
     gene            4268..4591
                     /locus_tag="RN951_003819"
                     /pseudo
     CDS             4268..4591
                     /locus_tag="RN951_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907654.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(4667..5473)
                     /locus_tag="RN951_003820"
                     /pseudo
     CDS             complement(4667..5473)
                     /locus_tag="RN951_003820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001485238.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="maturase"
     gene            complement(5491..5937)
                     /locus_tag="RN951_003821"
     CDS             complement(5491..5937)
                     /locus_tag="RN951_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001352292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase/maturase"
                     /protein_id="HDX2528750.1"
                     /translation="MPLTMEAVITRENLMLAYQRVVENKGAAGVDNLSVAELKPWLKK
                     NWRSVRQALIDGNYQPRAIRRMDIPKPDSGVRTSGIPTVVDRLIQQAIAQQLSAIVDK
                     SFSDSSYGFRPRRNAWKAVQQAQRYIRGGKRWVVDMEIWIWRSSST"
     gene            6834..7160
                     /locus_tag="RN951_003822"
     CDS             6834..7160
                     /locus_tag="RN951_003822"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528751.1"
                     /translation="METCFKVLQLKFDRKLSNRTIGLTLNISPSTVFEVLARFKASST
                     PWPLPETLTPEAIESLIFPEKKASVLIPVLPDWLHIDTEMRRPGVTRQLLWTEYRAQD
                     GKRALI"
     gene            complement(7370..7714)
                     /locus_tag="RN951_003823"
     CDS             complement(7370..7714)
                     /locus_tag="RN951_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001526830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528752.1"
                     /translation="MVDRMYVPPLASRRVKQTQIRSRDKWAETDLFVEQGVRYFFRVI
                     GKWCDMNHCCDANGYTVDYLNFARIWLRCRHEPATWFALIGTIDKSTDTMFVIGDGAR
                     LNNGWLRLAAVS"
     gene            complement(8069..9364)
                     /locus_tag="RN951_003824"
     CDS             complement(8069..9364)
                     /locus_tag="RN951_003824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001500024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2528753.1"
                     /translation="MSFIFVTYTVANADRANIGFAIPFIQEEFQISNTMAGLLISLFF
                     AGYAFFQIPAGYLIKKFGMRNAFAMGMLLTSVFTGLMGMVNNIFLLKILRFMVGICES
                     PVVIGSTVTINQWFPPKEKGTATGLFLAGSKFGPLIVPPLCAWIITVWGWRYIFVFFA
                     IPGLLLAIFWYLMVRNKPEESRFVNEQEVAYIREEQLPTTTQEAAAPVAPEFNYCWLD
                     KLIRTKQVEELSCSKQVFRCWDIYGVALGYFSMVGIVSVLMSWLPKYLITERGFDLTS
                     SAALAAAPFFGTVMGNFIGGVLSDRVLNKRRKPLMLLSAGATIFTMYALVYAPESKIV
                     LSLMLFLLGLMLSLGYSAYSVYAMGRANKDIYPIAYSVINMGGQLGGMCMPLIVGIIL
                     DAYNWDAVFMAMTGFCVLCFILVSTVIEPLSKNMKVNYR"
     gene            complement(9439..10356)
                     /locus_tag="RN951_003825"
     CDS             complement(9439..10356)
                     /locus_tag="RN951_003825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001498757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HDX2528754.1"
                     /translation="MSTFIQITEVGPRDGFQNIKAFIPTDLKIKIIDRLVESGIGAME
                     ITSMVSPKAIPQMRDAREVIQHVLNTHPHIIPSVLVPNVKGASLASEAGIQNINYVVS
                     VSPAHNKANINRTHAESLEDLYKIRHTFPEMTITLSLATVFGCPFIGETSRETLMDMI
                     KFADDLGISAVTLCDTIGVANPTQTLSVLRGIQQKFPKMDIGLHLHNTHGMALACMFA
                     GVQLGITRFETAVGGLGGCPFAPGAAGNAATEDAVNMFNRMGFDTGISLPDLLDIANL
                     IRSTIEPTLLSSLSRARTYSEFDFCSEKI"
     gene            complement(10368..11564)
                     /locus_tag="RN951_003826"
     CDS             complement(10368..11564)
                     /locus_tag="RN951_003826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001500023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HDX2528755.1"
                     /translation="MNKQSGVLSGVRVLDLTRVLAGPYCGMMLADFGADVIKIELPGK
                     GDDSRANAPQINGESAYFMNLNRNKRGMTLNLKSEEGRQIFLDLVRDSDVVLENYRPG
                     VMEKLGLGYEDLRKVNPAIIYGAVSGFGHTGPYSKRAGYDIIGQAMSGLMSTTGWPDT
                     PPTRTGTAIADVVGGMSCAIGVLAAYVNRLKTGVGEKVDIALVDSMVSSLEIINIIYL
                     NTGRIPTRIGNRYEAIYPYDSFQARDGYVIIACGNDKLYGLLKNVLQISALEDEKFKS
                     NLDRVAHHAELKEIIECWTRDLDIDTIVSMLLDAGIPSAPINTIDRVTQDPHIAGARE
                     MFVDIEHPVAGKITMTGNQVKFTHNKATIRMPAPTLGQHNYEVLKERLNYSDEKIEQL
                     IRSGIL"
BASE COUNT         2992 a         3149 c         2655 g         2863 t
ORIGIN      
        1 gatcacatta tcgtccactc caaatttgcg caactactgt agagtggtgt actccacagc
       61 ttcttttagg atctcaactt ccattgtttt cttaccgagc aagcactgca actcttttat
      121 ttatttgtag tggtcaacaa aaactggtca caatttcaga ttttttccag tatctatttt
      181 ccaattcgtt cggcggtaat ccgccgttat attcatgagg ccggagtgca ctataaaagt
      241 gtatgcgtaa accgactgct gtatgtagcc attaagccag tattggtaac ataggtaccc
      301 accttttcaa ctagtggaca cctgttatgg aacaaaaaac attatcagct gaaccccgca
      361 ggtcatgttc aaatgagttt aaacttcaaa tggttaaact ggctttacaa ccaagggttt
      421 ctgttgcctg cccgggagca tgatatcaat gataatcttc tgttcaaatg gctcaggctc
      481 tggctgatca aagggcgtat atcacggcgt cttccggtaa ggaactcttc tggcattggc
      541 gttgaattat tacctgtcga gatgacgctg gatgagcggc cttaccccgc tttttacgcg
      601 aggttattat gaagatcaat gactagccgt cgaaccgtgt gcatgaactg ctgcactgaa
      661 acttctcaac tgtaaaataa tccttacact acgtacttct cggagcgctt acgattaatc
      721 agatgcagtc ctaactggaa gaaagaaaaa tggaaaaaaa taagaggaat taatatcctc
      781 cacgttcctg aaatcctgga ggatattaat gtcattaaaa tattagcgaa cgataatccc
      841 taacaaaata cccagtgcgc caaagtcagc atcactgaag gtggtgttag caaaaccaat
      901 atcacccagc acaggcaata agaatactgg caggaaggta ataagcaagc cctgagcgaa
      961 ggcccccaaa atcgcaccac gacgtccacc cgttgcatta ccgaataccc ctgcagccgc
     1021 acctacgaag aagtgcggca ccacaccagg aataatcacg gtcatgttca gcagatacaa
     1081 catgaacata ccgattaaac ctgcagcaaa gctgctcagg aaaccaacca gtacagcgtt
     1141 aggtgcgtaa gggaagacga ccgggcaatc gagagcaggt ctggcattcg gaaccagctt
     1201 gtctgaaata cctttgaatg ccggaacaat ctccgcaatc accatacgca caccctgcag
     1261 aatgatgtac acgccagctg cgaaggtaat ggattgcatg atggagaaca tgaaccagtt
     1321 tttaccaccg ctaagctctt tcaccacatc tgccccggca aacaggcacg tcaccaggaa
     1381 aattatgctc atggtaaaag agatagcaac cggcgtgtcg cgcaagaaca gcagactttt
     1441 cggcacgttc atgtcttcag ccgagtgctc tttattacca aacttgctgc cgatgaaacc
     1501 ggccaataca taagataatg ttgagaagtg accgatggca acgtcatcag aaccggtcac
     1561 tttcttcatg tacggatgcg ctatagccgg gaaaaagacc attgccacgc caacaaccaa
     1621 agagccaacg gctataagcg taatgccagt catgcctgct gttgccagaa ttaccgctac
     1681 catcatcgac ataaacaacg tgtgatgacc ggtcaggaag ataaatttcc acggtgtgaa
     1741 acgggcaatc agaatgttga taaccatcgc aaagaacata atcattgcca tttctttccc
     1801 gaagcttttc tgcgctacgg aaacaatggc ttcattgttc ggcactacac cctgaatacc
     1861 aaaggcatgc tggaaaatgt ttgcgaagtc acccagtgac gacacaacta aacccgcccc
     1921 tgcgcctaaa atcacaaacc ccataatggt cttgacggta cctttaatgc attcggttac
     1981 cggttttttc tgtgcaatca ggccaatcag ggcgattaaa ccgaccagca ctgcgggttc
     2041 ggaaagtaca tcgctcatca aaaaacgaaa gaaatccata tcgcccccag cttacagtgc
     2101 gcctaattcg gttaatacca cggataaacg ttctctcatg gctttcttat caatcatatt
     2161 ttccagtgcg acgattttgc ctgcgacaga ctgcgcgact aactgctcgg caatgtcttt
     2221 ggtgccgaca tagatatcac tcggcgtccc tttcgcggag cccaggtcga cgtgatcaac
     2281 atcagcgctg acggacaaat ccttcaaaat gcttttaatg ctcatttcca tcatcaggct
     2341 ggtgcctaag ccgttaccgc aaaccactgt aattttcata aatgttcctc tggattaata
     2401 gcgcgcaata acagacaaaa tgtcctgcgt cgttttggcc atcaaaatgg cctgtatgtc
     2461 tttttcgtta tcgaataact tggcgagttg agaaatcgct tcaatgtggc tggtactgtc
     2521 ggttgcagcc agcacaatca gtaatttcac tggatcgttt tcatcggcat caaaattcac
     2581 acctgaaggg atcagggtca gtgctaatga cagcttgtta gctccctctt ccgggcgcgc
     2641 atgaggcatc gcaataccag ggccaaccac atagtacgga ccgatagtgt cgtgcgagcg
     2701 atagatcgca tcaacataac gcggttcgat agaaccgttt tcaatcaacg gccggcatga
     2761 aatcgccacg gcttcccgcc agtctttggc ctgttccacg acctgaacga cctctgtatt
     2821 taatagattt tttaacatgc tactgataac tcccgatgat aattaacagg agagtagata
     2881 ttttacgcat taattaatgt gatgattgtc gcatttgata gcgctatctg ataacgctac
     2941 caatctttgt gatagcgcta tcatttctct gccgccatgc tttggctata ttcggttcct
     3001 gcatatacaa tgcaacagga tatttgctac cgtgggcaaa aactggaaag agtaatggtg
     3061 aaataaaagt aatgaaaaca gctggttgta attatccatg gagtcgaaat ggaaaaaaca
     3121 cgtaagcgcc gtggtaccgg acgggtgacg ctgcaggagg tcgctaactt tgcaggtgtc
     3181 ggaaccatga ccgtttcccg tgcgctgaga acaccggaac aggtatctga caagctgagg
     3241 gaaaagatag aacaggccgt agaagagttg ggttatattc ccaacagaac tgctggcgcc
     3301 cttgcatctg gtcacagtga tacagtcgcc gtactggttc cttccctgac agataaagcc
     3361 agctcccgct ttatgcagtc gttgcagcag gtgcttaata aaaatgaatt ccagctactg
     3421 cttgggtgtc atgagtataa tcagctcaaa gaagctgaaa ttctgatgac gcttcttcaa
     3481 ggcaacccgg cggcgttagt tatttttggt tctcagttgg ctgataaaac tcaccagata
     3541 ctcgagaaaa caaatatacc taccattaac gttgtcggtt cccctttcag tccggctcaa
     3601 attaccatcg aaacagcatt ttttgaagca tcacataaac tgaccgaaca tctgctggaa
     3661 cagggttata agaatatcgg atttatcggt gcgcatatgg acaaccgcct gcaacgtcag
     3721 caactgaacg gctggcataa agcaatgttg agccattacc agaactctga tcttgttatc
     3781 accatgccgg atgccgcaag tctgcaattg gggcgttacg cattaaacga gatattactg
     3841 cgacaaccag agctggatgc tgtgatttgc agccacgaag agattgcgct gggtatcatg
     3901 tttgagtgcc agcggcgttt gttaaaaatt cctggaaata tcgctgtagc ttgtcttgat
     3961 ggttcagaca attgcgatca aacacaccca accttgacat ccatccgtat tgactacaaa
     4021 aaaatgggga tagagacggg taagttactg attgggctat tgaataataa tcatgatgaa
     4081 tcagaagagt cgcgtatcgt gcaattcaac taccagatag aattacgtca gagtacatga
     4141 gcctaaaagg gcactattac aaagttagct attgtggtag ggatagccgt ttccggctat
     4201 tccccgcgca gatccggatg tatgctgcta acgcatccat tcctacttca ggtatttggc
     4261 gtagaagcgg atgccaaaaa cttgccgcaa aaccgcaata tcagcctgca gagtcgctct
     4321 ccagattatc cattcctata ttatctctgc accggatgaa ttacgcgaac cactcagaaa
     4381 tatgacacgt atgcaactta tcaggactcc gggatcctgg aagcctagtg ccagtgaata
     4441 tcgtaatgtt accaacgttt atcgcattgc attgaaatca cttgcctgac gctatttcga
     4501 gttacatgat gaaatcgccg accttaatgt catgattgcg gcaattgtcg atgaactggc
     4561 acctgaactg attaaacgta atgctgttgg atcgagtagg aggcgggatc actcccgccg
     4621 tcctctcaca ccaccgtaca tgcggctccg catacggcgg ttcatgttaa cactggaact
     4681 gcctctgctg ttccagcagt gatatcagac cctgcctgct gaaccacgca ttctttatcg
     4741 cctgattcat atggcttgac cctgagttcc accatggccc gtggttgttg tacgctgaga
     4801 tcatcgccct gtccttactc agccccgctc ttagcaggtt cttcgtccga gttcccggcc
     4861 tcttctactg ccgccacaac aggcaccgca gtttccgttt gatccagccg tccagctctt
     4921 ccagcactcc tctgacttcc gtcagcctga agtagcttat ccatccacgc agcactggcg
     4981 tcagggcatt gattgtcact ttcactgatt tgctccggtt tcccgtggtc agactgcgga
     5041 ctttctcctt cagcctgttc acactcgtca gggctatttt cagcttcgcc tgtttgtgcc
     5101 atgtcacact gtacccgagg aacttccgct cccacgggcg cgccaccgcg ctcttcttct
     5161 cattcacctt cagtttcagt ttgttctcca cgaacgccct gatgttcttc agcagatggt
     5221 cgcccgcttt ccggctgctt acgtagatgt tgcagtcgtc tgcgtagcgg cagaagctgt
     5281 gtccacgacg ctccagttct ttatccagtt catccagcag gatgttcgac agtaacagcg
     5341 acagcgggcc gccctgcggc atgcccgcct gccgtttctc cctttgcccg tctttaacca
     5401 tttccgcttt caggtagcgg cgtatcagtc tcagcacccg cctgtccttt atcgttctgg
     5461 ccagacgcgt catcaggggt ctgtgatcca ctaggtcgaa gaacttctcc agatccatat
     5521 ctccatatcc accacccacc gtttgccacc ccgtatgtaa cgctgtgcct gttgcaccgc
     5581 cttccatgcg ttgcgcctcg gccggaagcc gtagctggag tctgagaagc ttttgtccac
     5641 gatggcgctt aactgctgcg ctatcgcctg ctggataagc ctgtccacca ccgtcgggat
     5701 gcctgaggtt ctcacgccgc tatccggctt cgggatatcc atccggcgta ttgcccgcgg
     5761 ctggtagttt ccgtcaatca atgcctgcct gacactgcgc cagttcttct tcagccacgg
     5821 tttcaactcc gccacgctga ggttatccac ccccgccgcg cctttgtttt ccaccacgcg
     5881 ctgataagcc agcatcaggt tttctctcgt tatcaccgct tccatcgtca gcggcacttc
     5941 cgctttcgtt tgcccacccg ccgccgtgct gatttcagcg ccatcatgca gccctgacgg
     6001 ataccgtccg tctcctctgc cgctggccgc agttgcctgc gcttatgctt tattaatcat
     6061 catcgggttc ggatgtccta atcacggtta atcatgttcg gccctgcatg ctgccagttt
     6121 tgcagcacta ctacggcgtc ggctgacttc tgccgcccca tcccggcacc ttacgacgcc
     6181 ggtagcacac tggcaggacg gcagatctcc cggggtaatt cgcgcgactt tcctgcttat
     6241 gcctgtcggc tctacgtcac agcgttccgt gtgagtatcg ggctttggtg atgtatgcca
     6301 ccttacccgc tgcgccgcct taaccgcttc ctgttcgtca ggccagcatt ttgcatccgg
     6361 cttccttcag atttcacctc gcgatgaaca cccttgcctt ccgctaacac ttcccctcac
     6421 cgggtgtgtg gaggactttc acctcttagt cgttcttcag ccaccacagt tgaagaacag
     6481 cgccagtcac ggcgctacgc gccatgcccg gcgcacatac cggaggcggt gatggcgggc
     6541 tcaccaccgc tgaacatcag cgtctgaaag agctggaacg tgaaaatcgt gcataatcgc
     6601 atctgaatcg atcaccaatt cgcatcacta tcgatcatca tttcgcatct cagtcgatca
     6661 ctgattcgca tggtggtcga tcactgtttc acatcttccg atcagcgatt cgcaccctgc
     6721 cgatcactcc gggaattaac acttttttgc atggtttcca ctgctgagtc tcgttgtctg
     6781 tggaggccat aatagctaaa aagaagaaat ccaggagcac tatgaggagc actatggaaa
     6841 catgttttaa agtcctgcag ctcaaattcg accggaagct gtccaacagg actatcgggc
     6901 tgacactaaa tatcagccct tccaccgtct ttgaggtgct ggctcgcttc aaagcatcat
     6961 caacgccatg gcccctgcca gaaacgctga cgccggaggc cattgaatcg cttatattcc
     7021 cggagaaaaa agcgtctgtg ctgataccgg tgctgcccga ctggcttcac attgataccg
     7081 aaatgcggcg accgggggtg acgcggcaac ttctgtggac ggaatacagg gctcaggacg
     7141 gaaaacgggc actgatataa atcaatttta aaggccggaa ttagccagct tttggtaaga
     7201 atccgacgaa gcgcacaaat accgactgct tttgtacact aaattttacg ccatagagaa
     7261 tacgtgtaat cagagagtaa tatcgacttc gcttttcatc gccagacttc cagcactacc
     7321 aaaccaaagt tattccagta catccctgaa atatcatttg caaagaccac taactcaccg
     7381 ctgcgaggcg caaccagccg ttatttagcc gggcaccgtc gccaatcaca aacatggtgt
     7441 cggttgattt atcgatagtg ccaattaagg caaaccaggt cgcaggttcg tggcggcaac
     7501 gcagccagat tcgggcaaaa ttcagatagt cgacggtata accattcgca tcgcaacaat
     7561 gattcatatc acaccacttt ccgatgacac gaaagaaata cctgacgccc tgctcaacaa
     7621 acaaatccgt ttcagcccat ttatcgcgtg agcgaatttg ggtttgcttc acccgccgtg
     7681 aagccagtgg cggaacgtac attcgatcaa ccatacatca tcacctttgt gcaaatacag
     7741 ataggcaggc cgtaaaagac cgcccggata aaacgatgac gaacagaagg gggaactcta
     7801 atttttatga actctgcggc cgtgctccat aactggaaag tcgtagtctt cgcgtgccgt
     7861 ttcatacctt tcattgactt ggcgcgatcg cacctacaga tgctcagtcc atttactgaa
     7921 ccgtgactgg ggttgccctt agcgtttaag caccaggaga gcgcaattca aatcagttat
     7981 ccaggccaga taacaacagt gatgggcgga acacccggac ggcgacgtgc ggataagcct
     8041 cgcgcttatc cgcacatcat cacggcggtt accggtagtt gaccttcata tttttcgaca
     8101 acggttcaat gaccgtggag accagaataa agcacagaac acagaacccg gtcatcgcca
     8161 tgaacaccgc atcccagttg taagcatcca gaataattcc cacaatcagt ggcatacaca
     8221 ttccgcccaa ctgaccaccc atgttgatca cgctgtaagc gatcgggtaa atgtctttat
     8281 tcgcccgccc catcgcgtag accgagtaag cggaataacc cagcgacagc atcagtccca
     8341 gcagaaacag catcagcgac agaacgattt tactttccgg cgcataaacc agcgcgtaca
     8401 tggtgaagat cgtcgcccct gcactgagca acatcagcgg tttacgacgc ttgttcagca
     8461 cccggtcaga aagcacgccg ccgataaagt tgcccattac cgtcccgaag aatggcgccg
     8521 ccgccagcgc ggcagaactc gtcagatcga atccgcgctc ggtgatcaga tacttgggta
     8581 gccaggacat tagcacgctg acgatcccca ccatcgagaa gtatcccagc gcgacaccat
     8641 aaatatccca gcagcggaag acctgttttg aacaggacag ttcttcaacc tgctttgtgc
     8701 gaatcagctt gtcgagccag cagtaattga actcaggcgc gacgggtgcg gcggcttcct
     8761 gggtcgtcgt cggaagctgt tcttcgcgga tgtaagcgac ctcttgctca ttaacgaagc
     8821 ggctttcttc cggcttattg cgaaccatca gataccagaa gatcgccaac agcaagccag
     8881 gaatggcaaa gaagacaaaa atatagcgcc atccccagac ggtgatgatc caggcgcaca
     8941 gcggcgggac gatcaacgga ccaaacttgg atcccgccag aaacagcccg gtcgctgtcc
     9001 ctttttcctt cggggggaac cactggttaa tcgtcaccgt cgagccaatg accaccggtg
     9061 actcacagat gcccaccata aaacgcagga tcttcagcag gaaaatgttg ttcaccatcc
     9121 ccatcaaccc cgtaaacacg gaggttaata acatacccat cgcaaaggca ttacgcatgc
     9181 cgaacttctt aatcaagtac ccggcaggga tctgaaaaaa cgcatatccg gcaaagaaca
     9241 ggctgattaa caacccggcc atggtattcg agatttgaaa ctcttcctga ataaaaggaa
     9301 tagcaaagcc gatatttgcg cggtcggcat tagccacggt gtaggttaca aagataaaac
     9361 tcatgaccca ccatctgtaa tgggtcatct tcggcttccc gatattatta ttcatcatgt
     9421 ctgtttccgt atcagaggtc agattttttc gctgcaaaaa tcaaattcac tgtaggttct
     9481 ggcacgtgaa agactgctca acaacgtcgg ctcaatcgtg ctgcggatca ggtttgcgat
     9541 atccagcagg tcaggcagtg agataccggt atcgaaaccc attcgattaa acatattcac
     9601 cgcatcctcg gtggcggcgt taccggcagc ccctggcgca aacgggcacc cgcccagtcc
     9661 accgacagcg gtctcaaagc gcgtgatgcc caactgaacg ccagcaaaca tacaggccag
     9721 cgccataccg tgggtgttat gcagatgcaa accgatgtcc attttgggga atttctgctg
     9781 gatcccacgc agaacggata acgtttgggt cgggttggcg acgccaatgg tatcgcacag
     9841 ggtaaccgcc gaaatcccga gatcatcggc aaacttgatc atatccatca gcgtttcacg
     9901 gctggtctcg ccaataaacg gacagccaaa taccgtcgcc agcgacagcg tgatggtcat
     9961 ctccgggaac gtgtggcgaa ttttataaag gtcctccagc gattcggcat gcgtccgatt
    10021 aatgttggcc ttgttatgcg ccgggctgac cgaaaccaca tagttaatat tttgaatgcc
    10081 tgcctcactg gcaagactgg cccctttcac attcggtact aacactgatg gaataatatg
    10141 cggatgcgtg ttcagaacat gctgaataac ctcacgagca tcacgcattt gcgggatcgc
    10201 tttcggactg accatcgagg tgatttccat cgcgccgatc cccgactcga ccagacgatc
    10261 gataattttt atttttaaat cggtaggaat aaacgctttg atgttctgaa aaccgtctct
    10321 tggcccgact tcagtaatct gaataaatgt cgacatagta gaatccctta cagaatgccg
    10381 gaacgaatga gctgctcaat tttttcatct gaatagttca gacgttcttt aagcacttcg
    10441 taattgtgtt gaccaagcgt gggcgcaggc attctgatgg tcgccttgtt atgtgtgaat
    10501 ttaacctgat tgccggtcat ggtaattttc cctgcgacgg ggtgttcaat atcgacaaac
    10561 atttcgcggg cgccagcaat atgcggatcc tgcgtcacgc ggtcgatggt attgatcggc
    10621 gcagaaggaa taccggcatc cagtagcatc gacacgatgg tgtcaatatc taaatcacgg
    10681 gtccagcatt cgataatttc tttcagctcg gcgtgatggg cgacgcggtc gaggttagat
    10741 ttaaatttct catcttccag cgcgctaatt tgcaggacgt ttttcagcag gccgtataat
    10801 ttatcgttgc cgcaggcaat aatgacgtaa ccgtcacgcg cctggaaaga gtcatacgga
    10861 taaattgctt catagcggtt accaatacgc gtcggaatac gtccggtatt aaggtaaata
    10921 atgttgataa tttccagcga cgacaccatc gaatcgacca gcgcaatatc cactttttct
    10981 ccgacgccgg ttttcaggcg gttgacgtaa gcggcaagca cgccaattgc gcaactcatt
    11041 cccccgacca catccgcaat agcggtcccg gtgcgggtag gcggcgtatc aggccaaccg
    11101 gtggtgctca tcagtccgct catggcctgg ccaataatgt cgtaacccgc gcgtttcgaa
    11161 tacggaccgg tatgaccaaa gccggatacg gcgccgtaaa taattgccgg attcacctta
    11221 cgtaaatcct catagccaag tcccagtttt tccatcacac ccggacggta attttccagt
    11281 accacgtcgc tgtcgcgaac taaatcaaga aatatctgcc gaccttcttc agatttaaga
    11341 ttcagcgtca ttccgcgctt attgcggttt aaattcataa agtaggcact ttcgccattg
    11401 atctgcggcg cgttggctcg tgaatcatcc ccttttcccg gcaattcgat tttaattaca
    11461 tctgcgccga aatccgccag catcattccg caataagggc cagccagcac ccgggttaaa
    11521 tccagcacac gaacgccact taatacacca gactgtttgt tcattctttc cctcactttt
    11581 ttattagata gagcacaagg ccgctcgcct tatagtttgt ctaatccaag atgtgtgcca
    11641 gaaatgaata aaacagaaa
//
LOCUS       DAPOAV010000112        11546 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.112, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000112 DAPOAV010000000
VERSION     DAPOAV010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11546
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.112"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..904
                     /gene="narU"
                     /locus_tag="RN951_003827"
     CDS             <1..904
                     /gene="narU"
                     /locus_tag="RN951_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="nitrate/nitrite transporter NarU"
                     /protein_id="HDX2528756.1"
                     /translation="SALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGS
                     VMSLANAAWIWVPLLAIATIAAWSGMNDIASSRASIADQLPVLQRLHLWLLSLLYLAT
                     FGSFIGFSAGFAMLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLIN
                     FIFMAIFSALLFLTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVIFRQITIY
                     RVKMKGGSDEQAHKEAVTETAAALGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKV
                     FLIFYIVCVLLTWLVYGRRKFSQK"
     gene            986..4726
                     /gene="narZ"
                     /locus_tag="RN951_003828"
     CDS             986..4726
                     /gene="narZ"
                     /locus_tag="RN951_003828"
                     /EC_number="1.7.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase Z subunit alpha"
                     /protein_id="HDX2528757.1"
                     /translation="MSKLLDRFRYFKQKGETFADGHGQVMHSNRDWEDSYRQRWQFDK
                     IVRSTHGVNCTGSCSWKIYVKNGLVTWEIQQTDYPRTRPDLPNHEPRGCPRGASYSWY
                     LYSANRLKYPLIRKRLIELWREALKQHSDPVLAWASIMNDPQKCLSYKQVRGRGGFIR
                     SNWQELNQLIAAANVWTIKTYGPDRVAGFSPIPAMSMVSYAAGTRYLSLLGGTCLSFY
                     DWYCDLPPASPMTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGT
                     KTIAITPDYSEVAKLCDQWLAPKQGTDSALAMAMGHVILKEFHLDNPSDYFINYCRRY
                     SDMPMLVMLEPRDDGSYVPGRMIRASDLVDGLGESNNPQWKTVAVNTAGELVVPNGSI
                     GFRWGEKGKWNLESIAAGTETELSLTLLGQHDAVAGVAFPYFGGIENPHFRSVKHNPV
                     LVRQLPVKNLTLVDGNTCPVVSVYDLVLANYGLDRGLEDENSAKDYAEIKPYTPAWGE
                     QITGVPRQYIETIAREFADTAHKTHGRSMIILGAGVNHWYHMDMNYRGMINMLIFCGC
                     VGQSGGGWAHYVGQEKLRPQTGWLPLAFALDWNRPPRQMNSTSFFYNHSSQWRYEKVS
                     AQELLSPLADASKYSGHLIDFNVRAERMGWLPSGPQLGRNPLGIKAEADKAGLSPTEF
                     TAQALKSGDLRMACEQPDSSSNHPRNLFVWRSNLLGSSGKGHEYMQKYLLGTESGIQG
                     EELGASDGIKPEEVEWQTAAIEGKLDLLVTLDFRMSSTCLFSDIVLPTATWYEKDDMN
                     TSDMHPFIHPLSAAVDPAWESRSDWEIYKGIAKAFSQVCVGHLGKETDVVLQPLLHDS
                     PAELSQPCEVLDWRKGECDLIPGKTAPNIVAVERDYPATYERFTSLGPLMDKLGNGGK
                     GISWNTQDEIDFLGKLNYTKRDGPAQGRPLIDTAIDASEVILALAPETNGHVAVKAWQ
                     ALGEITGREHTHLALHKEDEKIRFRDIQAQPRKIISSPTWSGLESDHVSYNAGYTNVH
                     ELIPWRTLSGRQQLYQDHPWMRAFGESLVAYRPPIDTRSVSEMRQIPPNGFPEKALNF
                     LTPHQKWGIHSTYSENLLMLTLSRGGPIVWISETDARELTIVDNDWVEVFNANGALTA
                     RAVVSQRVPPGMTMMYHAQERIMNIPGSEVTGMRGGIHNSVTRVCPKPTHMIGGYAQL
                     AWGFNYYGTVGSNRDEFIMIRKMKNVNWLDDEGRDQVQEAKK"
     gene            4723..6267
                     /gene="narH"
                     /locus_tag="RN951_003829"
     CDS             4723..6267
                     /gene="narH"
                     /locus_tag="RN951_003829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HDX2528758.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTGREGMEYAWFNNV
                     ETKPGIGYPKNWEDQEEWQGGWVRDVNGKIRPRLGNKMGVITKIFANPVVPQIDDYYE
                     PFTFDYEHLHSAPEGKHIPTARPRSLIDGKRMDKVIWGPNWEELLGGEFEKRARDRNF
                     EAMQKEMYGQFENTFMMYLPRLCEHCLNPSCVATCPSGAIYKREEDGIVLIDQDKCRG
                     WRLCISGCPYKKIYFNWKSGKSEKCIFCYPRIESGQPTVCSETCVGRIRYLGVLLYDA
                     DRIEEAASTEREVDLYERQCEVFLDPHDPSVIEEALKQGIPQNVIDAAQRSPVYKMAM
                     DWKLALPLHPEYRTLPMVWYVPPLSPIQSYADAGGLPKSEGVLPAIESLRIPVQYLAN
                     MLSAGDTGPVLRALKRMMAMRHYMRSQTVEGVTDTRAIDEVGLSVAQVEEMYRYLAIA
                     NYEDRFVIPTSHREMAGDAFAERNGCGFTFGDGCHGSDSKFNLFNSSRIDAINITEVR
                     DKAEGE"
     gene            6267..6962
                     /gene="narW"
                     /locus_tag="RN951_003830"
     CDS             6267..6962
                     /gene="narW"
                     /locus_tag="RN951_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HDX2528759.1"
                     /translation="MQILKVIGLLMEYPDELLWECKEDALALIRRDAPMLTDFTHNLL
                     NAPLLDKQAEWCEVFDRGRTTSLLLFEHVHAESRDRGQAMVDLLAEYEKVGLQLDCRE
                     LPDYLPLYLEYLSVLPDDQAKEGLLNVAPILALLGGRLKQREAPWYALFDALLQLAGS
                     SLSSDSVTKQVNSEERDDTRQALDAVWEEEQVKFIEDNATACDSSPLNQYQRRFSQDV
                     APQYVDISAGGGK"
     gene            6959..7639
                     /gene="narI"
                     /locus_tag="RN951_003831"
     CDS             6959..7639
                     /gene="narI"
                     /locus_tag="RN951_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HDX2528760.1"
                     /translation="MIQYLNVFFYDIYPYICATVFFLGSWLRYDYGQYTWRASSSQML
                     DKRGMVIWSNLFHIGILGIFFGHLFGMLTPHWMYAWFLPVAAKQLMAMVLGGICGVLT
                     LIGGAGLLWRRLTNQRVRATSTTPDIIIMSILLIQCLLGLSTIPFSAQYPDGSEMMKL
                     VGWAQSIVTFRGGSSEMLNGVAFVFRLHLVLGMTIFLLFPFTRLVHVWSAPFEYFTRR
                     YQIVRSRR"
     gene            7718..8611
                     /locus_tag="RN951_003832"
     CDS             7718..8611
                     /locus_tag="RN951_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
                     /protein_id="HDX2528761.1"
                     /translation="MKPQVYHVDAFTSQPFRGNSAGVVFPADNLSEAQMQLIARELGH
                     SETAFLLHSDDSDVRIRYFTPTVEVPICGHATVAAHYVRAKVLGLGNCTIWQTSLAGK
                     HRVTIEKHNDDYRISLEQGTPGFEPPLEGETRAAIINALHLTEDDILPGLPIQVATTG
                     HSKVMIPLKPEVDIDALSPDLNALTAISKKIGCNGFFPFQIRPGKNETDGRMFSPAIG
                     IVEDPVTGNANGPMGAWLVHHNVLPHDGNVLRVKGHQGRALGRDGMIEVTVTIRDNQP
                     EKVTISGTAVILFHAEWAIEL"
     gene            complement(8707..9552)
                     /gene="nhoA"
                     /locus_tag="RN951_003833"
     CDS             complement(8707..9552)
                     /gene="nhoA"
                     /locus_tag="RN951_003833"
                     /EC_number="2.3.1.118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-hydroxyarylamine O-acetyltransferase"
                     /protein_id="HDX2528762.1"
                     /translation="MTPILNHYFARINWSGAAAVNIDTLRALHLKHNCTIPFENLDVL
                     LPREIQLDNQSPEEKLVIARRGGYCFEQNGVFERVLRELGFNVRSLLGRVVLSNPPAL
                     PPRTHRLLLVELEEEKWIADVGFGGQTLTAPIRLVSDLVQTTPHGEYRLLQEGDDWVL
                     QFNHHQHWQSMYRFDLCEQQQSDYVMGNFWSAHWPQSHFRHHLLMCRHLPAGGKLTLT
                     NFHFTHYENGHAVEQRNLPDVASLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTH
                     PEAGK"
     gene            9725..10294
                     /locus_tag="RN951_003834"
     CDS             9725..10294
                     /locus_tag="RN951_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415979.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDX2528763.1"
                     /translation="MSRFIPIELHHASRLLNHGPTVLITSFDEQSQRRNIMAAAWSMP
                     VEFEPPRVAIVVDKSTWTRELIEHNGKFGIVIPGVAATNWTWAVGSVSGRDEDKFNCY
                     GIPVVRGPVFGLPLVEEKCLAWMECRLLPATSAQEEYDTLFGEVVSAAADARVFVEGR
                     WQFDDDKLNTLHHLGAGTFVTSGKRVTAG"
     gene            complement(10291..10524)
                     /gene="pptA"
                     /locus_tag="RN951_003835"
     CDS             complement(10291..10524)
                     /gene="pptA"
                     /locus_tag="RN951_003835"
                     /EC_number="5.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tautomerase PptA"
                     /protein_id="HDX2528764.1"
                     /translation="MPHIDIKCFPRELDEQQKAALAADITDVIIRHLNSKDSSISIAL
                     QQIQPESWQAIWDAEIAPQMEALIKKPGYSMNA"
     gene            complement(10624..>11546)
                     /locus_tag="RN951_003836"
     CDS             complement(10624..>11546)
                     /locus_tag="RN951_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISAs1-like element ISEc5 family transposase"
                     /protein_id="HDX2528765.1"
                     /translation="TIARVVSCISPAKFHECFINWMRDCHSSDDKDVIAIDGKTLRHS
                     YDKSRRRGAIHVISAFSTMHSLVIGQIKTDEKSNEITAIPELLNMLDIKGKIITTDAM
                     GCQKDIAEKIQKQGGDYLFAVKGNQGRLNKAFEEKFPLKELNNPAHDSYAMSEKSHGR
                     EEIRLHIVCDVPDELIDFTFEWKGLKKLCVAVSFRSIIAEQKKELEMTVRYYISSADL
                     TAEKFATAIRNHWHVENKLHWRLDVVMNEDDCKIRRGNAAELFSGIRHIAINILTNDK
                     VFKAGLRRKMRKAAMDRNYLASVLTGSGLS"
BASE COUNT         2712 a         3024 c         3045 g         2765 t
ORIGIN      
        1 gagcgctctt gggattaatg gcggattagg aaacttaggt gtaagtgtaa tgcagctggt
       61 tgcaccgctg gtcatttttg tacctgtatt tgcctttctc ggcgtcaatg gcgtaccgca
      121 ggccgacggt tcggtgatgt cgctggcgaa tgccgcatgg atttgggtac cgctactggc
      181 gattgccacg atcgccgcat ggtcagggat gaatgatatc gccagttcac gcgcctcaat
      241 tgccgaccag ctccctgtct tacaacgcct gcatctctgg ctgctgagcc tgctttacct
      301 tgccaccttc ggttcgttta tcggtttttc tgcgggtttt gccatgctgg caaaaaccca
      361 gttcccggat gtgaatattc tgcgcctggc gttctttggc ccatttatcg gtgccatcgc
      421 gcggtcggtt ggtggtgcta tttccgataa gttcggcggc gtgcgggtga cgttgatcaa
      481 ctttattttt atggcgattt tcagtgccct gctgttcctt accttaccgg gcacaggctc
      541 cggtaatttc atcgcctttt acgccgtatt tatggggctg tttctgactg cgggtctggg
      601 aagtggttct actttccaga tgatcgccgt catctttcgc cagataacca tttatcgggt
      661 aaagatgaaa ggcggtagtg atgagcaagc tcataaagaa gccgtcaccg aaacggcggc
      721 ggctctgggc tttatctcag ccattggcgc agtgggcggc ttttttattc cgcaggcgtt
      781 tggcatgtcg ctcaatatga ccggctctcc ggtcggcgcg atgaaagtgt ttttaatctt
      841 ctacatcgtt tgtgtgctgc tgacctggct ggtttatggt cggcggaagt tcagccaaaa
      901 ataagagatc gatgcctgat gtacaaccgt gtcgcatccg acaaggcatc agatcccaat
      961 tcattcctgg agcaggagtc atgtcatgag taaacttttg gatcgctttc gctacttcaa
     1021 acaaaagggc gaaacctttg ccgatggtca cggacaggtg atgcatagca accgcgactg
     1081 ggaggacagc tatcgccagc gttggcagtt cgacaaaatc gtgcgttcca cccacggtgt
     1141 taactgtaca ggctcctgta gctggaaaat ctacgttaaa aatggtctgg tgacctggga
     1201 aatccaacag accgactacc cgcgcactcg ccctgacctg cccaatcatg aacctcgcgg
     1261 ctgcccgcgt ggcgcaagtt actcctggta tctttacagc gctaaccgcc tgaaataccc
     1321 gctcattcgt aaacgactga ttgaactgtg gcgcgaagcc ctcaagcaac acagcgatcc
     1381 ggtactggcg tgggcatcga ttatgaacga tccgcaaaag tgcctgagct acaaacaagt
     1441 gcgtgggcgc ggcgggttta tccgctccaa ctggcaggaa ctaaaccagc tgattgccgc
     1501 cgctaacgtc tggaccatca aaacctacgg cccggatcgc gttgccggtt tctcgccgat
     1561 cccggcgatg tcgatggttt cttacgccgc cggaacgcgt tatctgtcgc tgcttggcgg
     1621 cacctgttta agtttctacg actggtattg cgacctgccg cccgcctcgc cgatgacctg
     1681 gggcgagcaa accgacgtac cggaatctgc cgactggtat aactccagct acatcatcgc
     1741 ctgggggtct aacgtaccgc agacacgtac gccggacgcc cacttcttta ccgaagtacg
     1801 ctacaaaggc actaaaacca tcgccattac ccctgactac tctgaagtgg ccaaattgtg
     1861 cgaccagtgg ctggcaccga aacaaggcac tgatagcgcc ctggcgatgg caatgggcca
     1921 tgtgatttta aaagagtttc atctcgataa tcccagcgac tactttatca actactgccg
     1981 ccgctacagc gacatgccga tgctggtaat gctggagcct cgcgacgatg gtagctacgt
     2041 tcccgggcgc atgatccgcg catctgacct ggtggatgga ctgggcgaaa gcaacaatcc
     2101 gcagtggaaa accgtagcag ttaataccgc aggtgaattg gtagtgccga acggttcgat
     2161 tggtttccgc tggggagaaa aaggcaaatg gaatctggaa tccattgccg ccggtacgga
     2221 aaccgaattg tcgttaaccc tgctcggtca acatgacgct gttgcaggcg tggccttccc
     2281 ctactttggc ggcattgaaa atccgcattt tcgcagcgta aaacacaatc cggtgctggt
     2341 gcgccaattg cccgttaaaa acctgacgtt agtcgatggc aacacctgtc cggtggtcag
     2401 cgtttatgat ttggtactgg cgaattacgg cctcgatcgc gggctggaag atgaaaacag
     2461 tgcgaaagat tacgctgaaa tcaaaccgta caccccagcc tggggtgagc aaattaccgg
     2521 cgtgccgcgc cagtatattg aaaccatcgc ccgtgaattt gccgataccg cccataaaac
     2581 gcatgggcgc tcgatgatta tcctcggcgc aggtgttaac cactggtatc acatggacat
     2641 gaactaccgc gggatgatca atatgctgat cttctgcggt tgtgtcgggc aaagcggtgg
     2701 cggctgggca cactatgtcg gccaggaaaa actgcgccca caaaccggct ggttgccact
     2761 ggcctttgcg ctcgactgga accgaccacc gcgccaaatg aacagcacct cgtttttcta
     2821 caatcattcc agccaatggc gctatgaaaa agtctctgct caggagttac tttcaccgct
     2881 cgccgatgcc agtaagtaca gcggtcatct gattgatttc aacgttcgcg ccgaacgtat
     2941 gggctggcta ccttctgggc cgcagctggg gcgtaacccg ctcgggatta aagctgaagc
     3001 cgacaaggcc ggattatccc ccacagaatt taccgcccag gcgctgaaat cgggcgattt
     3061 acgtatggcc tgcgaacaac cagatagcag cagcaatcat ccgcgtaatt tgtttgtctg
     3121 gcgctctaac ctgcttggct cctccggcaa aggccacgag tatatgcaga agtatctgct
     3181 ggggaccgaa agcgggattc agggcgagga actcggtgcc agcgacggga tcaaaccgga
     3241 agaagtcgag tggcaaactg cagcgattga aggcaagctc gacctgctgg tgacgctcga
     3301 cttccgcatg tccagtacct gcctgttctc cgatatcgtt ctgcccaccg ccacctggta
     3361 cgaaaaagac gatatgaaca cctcggatat gcatccgttt attcatccgc tttctgcggc
     3421 ggtcgatccg gcgtgggaat cacgcagcga ctgggaaatc tacaaaggta tcgccaaagc
     3481 attttcgcaa gtgtgcgtgg gtcatcttgg caaagaaacc gacgtggtat tacaacccct
     3541 actgcatgac tctccggcag agctctcaca gccgtgtgaa gtgctcgact ggcgcaaagg
     3601 cgaatgcgat ctgattccag gcaaaaccgc gccgaatatt gtggcggtgg agcgcgacta
     3661 ccctgctacg tatgaacgct ttacctcgct cgggccattg atggacaaac ttggcaatgg
     3721 cggtaaaggg atttcgtgga atacccagga tgaaatcgat ttcctcggca aactcaatta
     3781 caccaagcgt gatggcccgg cacaggggcg tccgctgatt gacaccgcca ttgacgcttc
     3841 agaagtgatt ctggcactgg caccggaaac caacggtcat gttgcagtca aagcgtggca
     3901 ggcgctgggc gagatcaccg ggcgcgaaca tacccatctg gcgctgcaca aagaggacga
     3961 gaagattcgc tttcgcgata ttcaggcgca gccgcgtaaa attatctcca gccccacctg
     4021 gtccggtctg gaaagcgatc acgtctccta taacgcggga tacaccaacg ttcatgagtt
     4081 aattccgtgg cgcacgctgt cgggacgcca gcagctctat caggatcatc cgtggatgcg
     4141 tgcttttggt gaaagcctgg tggcttatcg cccgcctatc gacacccgta gcgtcagtga
     4201 gatgcgccag ataccgccaa acggcttccc ggaaaaagca cttaacttcc tgacgccgca
     4261 ccagaaatgg ggcattcact caacctacag tgaaaacctg ctaatgctga cgctctctcg
     4321 cggtggaccg attgtctgga tcagcgaaac agatgcccga gaactgacca ttgtcgataa
     4381 cgactgggtg gaagtattca acgccaacgg cgcgctgact gcccgcgcgg tggtcagcca
     4441 acgtgtaccg ccgggcatga ccatgatgta tcacgcccag gaacgcatta tgaatattcc
     4501 tggttcggaa gtaactggca tgcgcggcgg cattcataac tcggttaccc gcgtttgccc
     4561 gaaaccaacg catatgattg gcggttacgc gcagctggcc tggggcttta actactacgg
     4621 caccgtcgga tcgaaccgcg atgagttcat catgatccgc aagatgaaga acgttaactg
     4681 gctggatgat gaaggtcgcg atcaggtaca ggaggcgaaa aaatgaaaat ccgttcacaa
     4741 gtcggcatgg tgcttaacct cgacaaatgt atcggctgcc atacctgttc ggtgacctgt
     4801 aaaaacgtct ggaccgggcg cgaaggcatg gagtacgcat ggtttaacaa cgtcgaaacc
     4861 aaaccgggca ttggttatcc gaaaaactgg gaagatcagg aagagtggca aggcggctgg
     4921 gtgcgtgatg tgaatggcaa gatacgcccg cgtctgggca acaagatggg cgtaataacc
     4981 aaaatcttcg ccaacccggt ggtgccgcag attgatgatt actacgaacc tttcaccttc
     5041 gactacgaac atttgcatag cgcaccggaa ggcaaacata ttcctactgc tcgcccgcgt
     5101 tcactgattg acggcaaacg gatggacaaa gtgatctggg ggccaaactg ggaagaactg
     5161 ctgggcggtg agttcgaaaa acgtgcccgc gaccgcaact tcgaggccat gcaaaaggag
     5221 atgtacgggc agtttgaaaa caccttcatg atgtacctgc cgcgcctgtg cgaacactgc
     5281 ctcaatccca gctgcgtggc gacctgccca agcggcgcta tctacaaacg cgaagaagac
     5341 ggcattgtgc tgattgatca ggataaatgc cgtggctggc gtttgtgcat aagcggttgt
     5401 ccgtacaaaa aaatctactt caactggaaa agcggcaagt cagaaaaatg catcttctgt
     5461 tacccacgaa ttgagtccgg tcaaccgacc gtgtgctcag aaacctgcgt gggtcgcatc
     5521 cggtatctgg gcgtgctgct ttacgacgcc gaccgcatcg aggaagcggc gagcaccgag
     5581 cgcgaagttg acctctatga acgccagtgc gaagtgttcc tcgatccaca cgatccctca
     5641 gtgatcgagg aagccctgaa acaaggtatt ccacaaaatg tgattgacgc tgcccagcgt
     5701 tcgccagtct acaaaatggc gatggactgg aaactggcac taccgttgca ccctgaatac
     5761 cgcaccctgc cgatggtctg gtacgttcct ccgctgtcac cgattcagtc ctacgcagat
     5821 gcgggcggtt tgccgaaaag cgaaggcgtg ctgcccgcca tcgaaagcct gcgtattccg
     5881 gtgcaatatc tcgccaatat gttgagtgcc ggcgataccg gtccggtact gcgggcgctg
     5941 aaacggatga tggcgatgcg ccactatatg cgttcacaaa ccgtggaagg cgttactgat
     6001 actcgtgcca tcgacgaagt aggcctgagc gtcgcccagg tcgaagagat gtatcgctat
     6061 ctcgccattg ccaactatga agatcgtttt gttatcccga ccagccatcg ggaaatggcg
     6121 ggcgatgcct tcgcagaacg caacggctgc ggttttacct ttggcgacgg ttgccacggt
     6181 tcggacagta aattcaacct gttcaacagt agccgtatcg atgccatcaa catcaccgaa
     6241 gtgcgcgaca aagcggaggg cgaataatgc agatcctcaa agtgatcggc ctgttgatgg
     6301 agtatccgga cgagctgttg tgggaatgca aggaggacgc gctggcgttg atccgccgcg
     6361 acgcgccgat gcttacggat ttcacccaca acctgcttaa cgcgccgctg ctggataaac
     6421 aggccgaatg gtgcgaagtg tttgaccgcg ggcgcaccac gtcgctgctg ctgttcgaac
     6481 atgttcatgc cgagtcccgc gatcgcggcc aggcaatggt ggacctgctg gcggagtatg
     6541 aaaaggtcgg cctgcagctg gattgtcggg aactgcccga ttatctaccg ctgtatctgg
     6601 agtatttaag cgtactgcct gacgatcagg cgaaagaagg attgctcaat gttgcgccga
     6661 tcctcgccct gcttggcggt cgcttaaaac aacgcgaggc accgtggtac gcgttgtttg
     6721 atgctctgct gcaactggcg ggaagctccc tttcaagtga cagtgtcaca aaacaagtaa
     6781 acagcgaaga gcgcgatgac acccgccagg cgcttgatgc agtgtgggaa gaggaacagg
     6841 tgaagtttat tgaagataac gccacggcgt gtgacagctc gccgcttaat caatatcagc
     6901 gacgctttag ccaggatgtc gcgccgcaat atgtcgacat cagtgcggga ggtgggaaat
     6961 gattcagtat ctgaacgtct ttttttacga tatctacccg tacatttgtg cgacggtgtt
     7021 tttcctcggc agctggctgc gctacgacta cgggcagtac acctggcgcg cctcctcaag
     7081 tcaaatgctc gataaacgcg ggatggtgat atggtcgaat ctgttccata tcggcatttt
     7141 ggggattttc ttcgggcact tgttcggcat gttaacgccg cactggatgt acgcgtggtt
     7201 tttgccagtg gcagcgaaac aactcatggc gatggtgctc ggcggtattt gcggtgtgtt
     7261 gacgttgatt ggcggcgcag gactgctgtg gcgcaggctg acaaatcagc gcgtgcgtgc
     7321 cacttccact acgccggata tcatcatcat gagcattttg ctgatccagt gtctgttggg
     7381 gctaagtacc ataccgtttt cagcacagta tcctgatggt agcgaaatga tgaagctggt
     7441 gggttgggcg caaagcattg tcactttccg tggtggatcg tcagagatgc tcaacggcgt
     7501 agcgttcgtc ttccgcctgc atctggtgtt gggaatgacc atcttcctgc tcttcccgtt
     7561 cacccgactg gtgcatgtgt ggagcgcgcc gtttgagtac tttactcgtc gatatcaaat
     7621 tgtgcgttcg cggcgataat ttcaccctgg ccggatagcc cttcgctctc cggccacttg
     7681 caggctatga tagttctcca gtcacaggag aacgttaatg aaaccgcagg tgtaccacgt
     7741 cgatgctttt acctcacaac cgtttcgcgg caattctgcc ggtgttgttt tccccgccga
     7801 taatcttagc gaagcgcaaa tgcagcttat cgcccgcgag ttaggccatt cggaaactgc
     7861 ttttctgctg cacagcgacg acagcgatgt gcgcatccgc tactttacgc caacggttga
     7921 agtgccgatt tgcggtcacg cgacagtagc tgcgcactat gtacgtgcga aggtgttagg
     7981 tttaggaaat tgcacgatct ggcaaacatc gctggcagga aaacatcgcg tgactatcga
     8041 aaagcacaac gatgattatc gtatttcgct ggaacaaggt acgccgggct ttgagccacc
     8101 gctggaaggt gaaacacgtg cggcgattat caacgcgctt catctcactg aggacgatat
     8161 tctgccaggc ttgccaattc aggtggcaac aacaggacac tcaaaagtga tgatcccact
     8221 gaaaccggaa gtggatatcg acgccctttc gcctgacctt aatgcgctga ccgctatcag
     8281 caaaaagatt ggctgcaatg gtttcttccc gttccagatc cgcccaggca aaaacgaaac
     8341 cgatggtcgc atgttctcgc ctgcgattgg tattgtggaa gatccggtga ctggcaatgc
     8401 caatggcccg atgggtgcat ggttggtaca tcacaacgta ttgccccacg atggcaacgt
     8461 gttgcgtgtt aaaggccatc aggggcgcgc attggggcgt gacggtatga ttgaagtgac
     8521 ggtgacaatt cgtgataacc aaccggaaaa agtcaccatt tcaggcacag cggtgatttt
     8581 gtttcatgcc gaatgggcaa ttgaactctg aaaccgttgt ctgatgcgct tcgcctgtca
     8641 ggtctacaac cgggctaatg tatgccggat aaggcgttta cgccgcatcc ggcaacctga
     8701 cataaattat tttcccgcct ccgggtgcgt atcaaacgcc gccatcacca gcgctaactc
     8761 atccacggta aagccatgtt tcgcatcatc cacgcccaga ccaaactgtt cttgcatcac
     8821 agcatataat gacgccacat ccggtagatt tcgctgctcc accgcgtgcc cattttcata
     8881 atgggtaaaa tgaaaattgg tcagtgtcag cttgccgccg gccggcaaat ggcggcacat
     8941 cagcaaatga tggcgaaaat gcgactgcgg ccagtgcgcc gaccagaaat tgcccatcac
     9001 ataatcgctt tgttgctgct cgcagagatc aaaacggtac atcgactgcc aatgctgatg
     9061 atgattaaac tgcaacaccc aatcatcacc ctcctgcaac aaccgatact ctccgtgtgg
     9121 cgtggtctgc acgagatcgg aaactaaacg aatcggcgcg gttagcgtct gcccaccgaa
     9181 accgacatca gcaatccatt tttcctcttc cagttccacc aacagcaaac gatgggtgcg
     9241 cggcggtaat gctggcggat ttgataacac tacgcgccct aacaagctgc gaacgttaaa
     9301 ccccagctcg cgtaacaccc gctcaaacac gccattctgc tcaaaacagt aaccgccacg
     9361 acgggctatc accagtttct cttccggcga ttgattatca agctgtattt ccctcggcag
     9421 caaaacgtcg aggttttcaa acggaatggt gcaattgtgt ttcaggtgca atgcacgaag
     9481 cgtatcaata ttgaccgcag cagctcccga ccagttaata cgggcaaaat agtgattcag
     9541 aatgggcgtc atcaggcgtt tcccttagtg gttttctcaa cttataacct ggaatagacg
     9601 ccgcaccggc tattttgtgc gatcgcggac atgcatcacg ttcgcaaatc gccaatcccg
     9661 ttaatttcgt tacttattgc gttacggact acgcttaaaa aaaccttctt cgcgaggcga
     9721 taccatgagc cgattcatcc ccatagaatt acaccatgcc agccgtctgt taaatcatgg
     9781 cccaacggtc ttgatcacca gtttcgatga gcaatcccag cggcgtaaca ttatggctgc
     9841 agcctggtca atgccggtgg agtttgaacc tccacgcgtg gcgattgtgg tagataaatc
     9901 gacatggacc agggagttga ttgaacataa cggtaaattt ggcatcgtta tcccgggcgt
     9961 tgcagcaact aactggacgt gggcggtggg aagtgtgtcg gggcgtgatg aagataaatt
    10021 taattgctat ggcattccgg ttgtgagagg cccggtattt ggtttgcctc tggtcgagga
    10081 aaaatgtctg gcgtggatgg agtgtcgatt gctacctgcg acttctgcgc aagaagaata
    10141 cgacacgctg tttggcgaag tagtatcagc agcggcagac gcacgggtat ttgtcgaagg
    10201 ccgctggcag tttgatgatg ataagctcaa tacgttgcat catttaggtg ctgggacgtt
    10261 tgttaccagc ggcaagcgtg ttacggcggg ttaagcattc atgctataac caggtttctt
    10321 tatcaaagcc tccatttggg gcgcgatttc ggcatcccag atagcttgcc aagattctgg
    10381 ttgaatctgc tgtagagcaa tgcttatcga actgtcttta ctgttcagat gacgaataat
    10441 aacgtcggta atatctgcag caagtgctgc tttttgttgt tcgtccagtt cacgcggaaa
    10501 acatttaatg tcgatgtgcg gcatgattac gctccttttg aaagatgtca gtaaaattaa
    10561 cacacattgt gaatgtcatg tgtccggtaa agcgtttata cgacaataat gcccagggca
    10621 agattacgaa agcccgctcc ccgtaaggac tgacgccagg tagtttctgt ccatggctgc
    10681 ttttcgcatc ttacgtctta accctgcctt gaatacctta tcattcgtca aaatattaat
    10741 agcaatgtgc cgtatccctg aaaataattc tgctgcattt cctcttctta ttttgcagtc
    10801 gtcttcattc attaccacgt ccagacgcca gtgcagctta ttctccacat gccagtggtt
    10861 tcggattgct gtggcgaact tctctgcggt taaatcagca gaactgatat aatatctgac
    10921 cgtcatttcg agctctttct tttgttctgc tattatggac cgaaaggaga ctgccacgca
    10981 taatttcttc agccctttcc attcaaacgt gaaatcaata agttcatcag ggacatcgca
    11041 aacaatatga agacggattt cttctctgcc gtgactcttt tcactcattg cgtaactgtc
    11101 atgcgctgga ttatttaatt ctttcagcgg aaatttttcc tcaaaggctt tatttagccg
    11161 cccctggttt ccttttaccg cgaataaata atcacctccc tgtttttgta tcttctctgc
    11221 aatatctttc tggcaaccca tcgcatcagt tgtgatgatt tttcctttaa tatccagcat
    11281 gttaagaagt tctgggatag ctgtaatctc attagatttc tcatccgtct tgatctgtcc
    11341 gatgaccaga ctgtgcattg ttgagaacgc actaatgaca tgaatcgctc ccctgcggcg
    11401 actcttatca taagaatgcc ggagcgtttt tccatcaatt gcaatgacgt ctttatcatc
    11461 tgaagaatgg cagtcacgca tccagttaat aaagcactcg tgaaattttg caggactgat
    11521 acaggataca actctggcaa tggtgt
//
LOCUS       DAPOAV010000113        11535 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.113, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000113 DAPOAV010000000
VERSION     DAPOAV010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11535
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.113"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..892
                     /locus_tag="RN951_003837"
     CDS             <1..892
                     /locus_tag="RN951_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX2528766.1"
                     /translation="NIELRHLRYFVAVAEELHFGRAAARLNISQPPLSQQIQALEQQI
                     GARLLARTNRSVLLTAAGKQFLADSRQILSMVDDAAARAERLHQGEAGELRIGFTSSA
                     PFIRAVSDTLSLFRRDYPDVHLQTREMNTREQIAPLIEGTLDMGLLRNTALPESLEHA
                     VIVHEPLMAMIPHDHPLANNPNVTLAELAKEPFVFFDPHVGTGLYDDILGLMRRYHLT
                     PVITQEVGEAMTIIGLVSAGLGVSILPASFKRVQLNEMRWVPIAEEDAVSEMWLVWPK
                     HHEQSPAARNFRIHLLNALR"
     gene            1027..2247
                     /gene="mlc"
                     /locus_tag="RN951_003838"
                     /gene_synonym="dgsA"
     CDS             1027..2247
                     /gene="mlc"
                     /locus_tag="RN951_003838"
                     /gene_synonym="dgsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor Mlc"
                     /protein_id="HDX2528767.1"
                     /translation="MVAENQPGHIDQIKQTNAGAVYRLIDQLGPVSRIDLSRLAQLAP
                     ASITKIVREMLEAHLVQELEIKEAGNRGRPAVGLVVETEAWHYLSLRISRGEIFLALR
                     DLSSKLVVEESQELALKDDLPLLDRIISHIDQFFIRHQKKLERLTSIAITLPGIIDTE
                     NGIVHRMPFYEDVKEMPLGEALEQHTGVPVYIQHDISAWTMAEALFGASRGARDVIQV
                     VIDHNVGAGVITDGHLLHAGSSSLVEIGHTQVDPYGKRCYCGNHGCLETIASVDSILE
                     LAQLRLNQSMSSMLHGQPLTVDSLCQAALRGDLLAKDIITGVGAHVGRILAIMVNLFN
                     PQKILIGSPLSKAADILFPVISDSIRQQALPAYSQHISVESTQFSNQGTMAGAALVKD
                     AMYNGSLLIRLLQG"
     gene            2372..3067
                     /gene="bioD"
                     /locus_tag="RN951_003839"
     CDS             2372..3067
                     /gene="bioD"
                     /locus_tag="RN951_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310326.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent dethiobiotin synthetase BioD"
                     /protein_id="HDX2528768.1"
                     /translation="MLKRFFITGTDTSVGKTVVSRALLQALASQGKTVAGYKPVAKGS
                     KETPEGLRNKDALVLQSVSTIELPYEAVNPIALSEEESSVAHSCPINYTLISNGLANL
                     TEKVDHVVVEGTGGWRSLMNDLRPLSEWVVQEQLPVLMVVGIQEGCINHALLTAQAIA
                     NDGLPLIGWVANRINPGLAHYAEIIDVLGKKLPAPLIGELPYLPRAEQRELGQYIRLA
                     MLRSVLAVDRVTV"
     gene            complement(3020..4312)
                     /gene="clcB"
                     /locus_tag="RN951_003840"
     CDS             complement(3020..4312)
                     /gene="clcB"
                     /locus_tag="RN951_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated ClC-type chloride channel ClcB"
                     /protein_id="HDX2528769.1"
                     /translation="MHHLHIYPDLRTMFRRLLIATVVGILAAFAVAGFRHAMLLLEWL
                     FLNNDSGSLVNAATNLSPWRRLLTPALGGLAAGLLLMGWQKFTQQRPHAPTDYMEALQ
                     TDGQFDYAASLVKSLASLLVVTSGSAIGREGAMILLAALAASCFAQRFTPRQEWKLWI
                     ACGAAAGMAAAYRAPLAGSLFIAEVLFGTMMLASLGPVIISAVVALLVSNLINHSDAL
                     LYNVQLSVTVQARDYALIISTGVLAGLCGPLLLTLMNACHRGFVSLKLAPPWQLALGG
                     LIVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAGIFLCKLCAVLASSGSGAPGGVF
                     TPTLFIGLAIGMLYGRSLGLWFPDGEEITLLLGLTGMATLLAATTHAPIMSTLMICEM
                     TGEYQLLPGLLIACVIASVISRTLHRDSIYRQHTAQHS"
     gene            complement(4471..5085)
                     /gene="dmsD"
                     /locus_tag="RN951_003841"
     CDS             complement(4471..5085)
                     /gene="dmsD"
                     /locus_tag="RN951_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707489.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tat proofreading chaperone DmsD"
                     /protein_id="HDX2528770.1"
                     /translation="MTHFSQQDNFSVAARVLGALFYYAPESAEAAPLVAVLTSDGWET
                     QWPLPEASLAPLVTAFQTQCEETHAQAWQRLFVGPWALPSPPWGSVWLDRESVLFGDS
                     TLALRQWMREKGIQFEMKQNEPEDHFGSLLLMAAWLAENGRQTECEELLAWHLFPWST
                     RFLDVFIEKAEHPFYRALGELARLTLAQWQSQLLIPVAVKPLFR"
     gene            complement(5128..5982)
                     /locus_tag="RN951_003842"
     CDS             complement(5128..5982)
                     /locus_tag="RN951_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit"
                     /protein_id="HDX2528771.1"
                     /translation="MGNGWHEWPLVIFTVLGQCVVGALIVSGIGWFAAKNDADRQRIV
                     RGMFFLWLLMGVGFIASVMHLGSPLRAFNSLNRIGASGLSNEIAAGSIFFAVGGLWWL
                     VAVIGKMPQALGKLWLLFSMALGVIFVWMMTCVYQIDTVPTWHNGYTTLAFFLTVLLS
                     GPILAAAILRAARVTFNTTPFAIISVLALIACAGVIVLQGLSLASIHSSVQQASALVP
                     DYASLQVWRVVLLCAGLGCWLCPLIRRREPHVAGLILGLILILGGEMIGRVLFYGLHM
                     TVGMAIAG"
     gene            complement(5984..6601)
                     /gene="dmsB"
                     /locus_tag="RN951_003843"
     CDS             complement(5984..6601)
                     /gene="dmsB"
                     /locus_tag="RN951_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HDX2528772.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDFKDLGPEVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCDDPACTKVCPSGAMHKREDGFVVVDEDVCIGC
                     RYCHMACPYGAPQYNAEKGHMTKCDGCYSRVAEGKQPICVESCPLRALEFGPIEELRQ
                     KHGTLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPEEV"
     gene            complement(6612..9035)
                     /locus_tag="RN951_003844"
     CDS             complement(6612..9035)
                     /locus_tag="RN951_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416105.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase subunit A"
                     /protein_id="HDX2528773.1"
                     /translation="MKIHTTEALMKAEISRRSLMKTSALGSLALASSAFTLPFSQMVR
                     AAEAPVEEKAVWSSCTVNCGSRCLLRLHVKDDTVYWVESDTTGDDVYGNHQVRACLRG
                     RSIRRRMNHPDRLKYPMKRVGKRGEGKFERISWDEALDTISDNLRRILKDYGNEAVHV
                     LYGTGVDGGNITNSNVPYRLMNSCGGFLSRYGSYSTAQISAAMSYMFGANDGNSPDDI
                     ANTKLVVMFGNNPAETRMSGGGVTYYVEQARERSNARMIVIDPRYNDTAAGREDEWLP
                     IRPGTDGALACAIAWVLITENMVDQPFLDKYCVGYDEKTLPANAPRNAHYKAYILGEG
                     PDGIAKTPEWAAKITSIPAEKIIQLAREIGSAKPAYICQGWGPQRHSNGEQTSRAIAM
                     LSVLTGNVGINGGNSGVREGSWDLGVEWFPMLENPVKTQISVFTWTDAIDHGTEMTAT
                     RDGVRGKEKLDVPIKFLWCYASNTLINQHGDINHTHEVLQDDSKCEMIVGIDHFMTAS
                     AKYCDILLPDLMPTEQEDLISHESAGNMGYVILAQPATSAKFERKPIYWMLSEVAKRL
                     GPDVYQTFTEGRSQHEWIKYLHAKTKERNPEMPDYEEMKTTGIFKKKCPEEHYVAFRA
                     FREDPQANPLKTPSGKIEIYSERLAKIADTWELKKDEIIHPLPAYTPGFDGWDDPLRK
                     TYPLQLTGFHYKARTHSSYGNIDVLQQACPQEVWINPIDAQARGIRHGDTVRVFNNNG
                     EMLIAAKVTPRILPGVTAIGQGAWLKADMFGDRVDHGGSINILTSHRPSPLAKGNPSH
                     SNLVQIEKV"
     gene            complement(9096..11522)
                     /locus_tag="RN951_003845"
     CDS             complement(9096..11522)
                     /locus_tag="RN951_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase subunit A"
                     /protein_id="HDX2528774.1"
                     /translation="MSKNERMVGISRRTLVKSTAIGSLALAAGGFSLPFTLRNAAAAV
                     QQAREKVVWGACSVNCGSRCALRLHVKDNEVTWVETDNTGSDEYGNHQVRACLRGRSI
                     RRRINHPDRLNYPMKRVGKRGEGKFERISWDEALDTIASSLKKTVEQYGNEAVYIQYS
                     SGIVGGNMTRSSPSASAVKRLMNCYGGSLNQYGSYSTAQISCAMPYTYGSNDGNSTTD
                     IENSKLVVMFGNNPAETRMSGGGITYLLEKAREKSNAKMIVIDPRYTDTAAGREDEWL
                     PIRPGTDAALVAGIAWVLINENLVDQPFLDKYCVGYDEKTLPADAPKNGHYKAYILGE
                     GDDKTAKTPQWASQITGIPEDRIIKLAREIGTAKPAYICQGWGPQRQANGELTARAIA
                     MLPILTGNVGISGGNSGARESTYTITIERLPVLDNPVKTSISCFSWTDAIDHGPQMTA
                     IRDGVRGKDKLDVPIKFIWNYAGNTLVNQHSDINKTHEILQDESKCEMIVVIENFMTS
                     SAKYADILLPDLMTVEQEDIIPNDYAGNMGYLIFLQPVTSEKFERKPIYWILSEVAKR
                     LGPDVYQKFTEGRTQEQWLQHLYAKMLAKDPALPSYDELKKMGIYKRKDPNGHFVAYK
                     AFRDDPEANPLKTPSGKIEIYSSRLAEIARTWELEKDEVISPLPVYASTFEGWNSPER
                     RTFPLQLFGFHYKSRTHSTYGNIDLLKAACRQEVWINPIDAQKRGIANGDMVRVFNHR
                     GEVRLPAKVTPRILPGVSAMGQGAWHEANMSGDKIDHGGCVNTLTTLRPSPLAKGNPQ
                     HTNLVEIEKI"
BASE COUNT         2779 a         2960 c         2997 g         2799 t
ORIGIN      
        1 gaatattgaa cttcgtcatc tgcgttactt tgttgctgtt gcggaagagc tgcatttcgg
       61 gcgcgccgct gcccgcctga atatttcgca accgccgcta agtcagcaga ttcaggcgct
      121 ggagcaacaa attggtgccc gactgctggc acgaaccaat cgcagtgtat tgctgacggc
      181 agcaggaaaa cagtttcttg cagatagtcg gcaaatcctg tctatggtgg atgacgctgc
      241 cgctcgcgct gaaaggctgc atcagggtga agcgggggag ttgcgcattg gttttacttc
      301 gtcggctcct tttattcggg cggtgtccga tacgttatcg ctgtttcgcc gtgattatcc
      361 tgatgtccat ttacaaaccc gcgaaatgaa cactcgcgag caaatcgctc cgctcattga
      421 aggaacgctg gatatgggat tgctgcgtaa cacagcgtta ccggagtcgc ttgaacacgc
      481 agtcatcgtc catgaaccgc ttatggcgat gatcccgcac gatcatcccc tggcaaataa
      541 cccgaatgta acgctggctg aactggcgaa agaacccttt gtcttttttg atccgcacgt
      601 cgggacaggg ctgtatgacg atattctcgg gctgatgcga cgttaccatt tgacgcccgt
      661 catcactcag gaggtgggcg aggcaatgac catcatcggt ctggtttccg ccggtctggg
      721 tgtttcaatt ttgcctgcgt catttaaacg tgttcagctc aacgaaatgc gctgggtgcc
      781 gattgctgaa gaggatgcgg tttctgaaat gtggttggtc tggccgaaac atcatgaaca
      841 aagtccggct gcgcgtaact ttcgtattca tctgctgaat gctctcaggt gagggaaatt
      901 tcagcgaaaa agcccgaaaa atgtgctgtt aatcacatgc ctaagtaaaa atttgacgac
      961 acgtattgaa gtgcttcacc atagcctaca gattatttcg gagcgcgaaa atatagggag
     1021 tatgcggtgg ttgctgaaaa ccagcctggg cacattgatc aaataaagca gaccaacgcg
     1081 ggcgcggttt atcgcctgat tgatcagctt ggtccagtct cgcgtatcga tctttcccgt
     1141 ctggcgcaac tggctcctgc cagtatcact aaaattgtcc gtgagatgct cgaagcacac
     1201 ctggtgcaag agctggaaat caaagaagcg gggaaccgtg gccgtccggc ggtggggctg
     1261 gtggttgaaa ctgaagcctg gcactatctt tctctgcgca ttagtcgcgg ggagattttc
     1321 cttgctctgc gcgatctgag cagcaaactg gtggtggaag agtcgcagga actggcgtta
     1381 aaagatgact tgccattgct ggatcgtatt atttcccata tcgatcagtt ttttatccgc
     1441 caccagaaaa aacttgagcg tctaacttcg attgccataa ccttgccggg aattattgat
     1501 acggaaaatg gtattgtaca tcgcatgccg ttctacgagg atgtaaaaga gatgccgctc
     1561 ggcgaggcgc tggagcagca taccggcgtt ccggtttata ttcagcatga tatcagcgca
     1621 tggacgatgg cagaggcctt gtttggtgcc tcacgcgggg cgcgcgatgt gattcaggtg
     1681 gttatcgatc acaacgtggg ggcgggcgtc attaccgatg gtcatctgct acacgcaggc
     1741 agcagtagtc tcgtggaaat aggccacaca caggtcgacc cgtatgggaa acgctgttat
     1801 tgcgggaatc acggctgcct cgaaaccatc gccagcgtgg acagtattct tgagctggca
     1861 cagctgcgtc ttaatcaatc catgagctcg atgttacatg gacaaccgtt aaccgtggac
     1921 tcattgtgtc aggcggcatt gcgcggcgat ctactggcaa aagacatcat taccggggtg
     1981 ggcgcgcatg tcgggcgcat tcttgccatc atggtgaatt tatttaaccc acaaaaaata
     2041 ctgattggct caccgttaag taaagcggca gatatcctct tcccggtcat ctcagacagc
     2101 atccgtcagc aggcccttcc tgcgtatagt cagcacatca gcgttgagag tactcagttt
     2161 tctaaccagg gcacgatggc aggcgctgca ctggtaaaag acgcgatgta taacggttct
     2221 ttgttgattc gtctgttgca gggttaacat tttttaactg ttctaccaaa atttgcgcta
     2281 tctcaatttg ggccaggaaa gcataactta gactttcaag gttaattatt ttcctggttt
     2341 atatttgtga agcataacgg tggagttagt gatgctgaag cgtttcttta ttaccggtac
     2401 agacacttct gtagggaaaa cggtggtttc ccgcgcattg ctacaagcgt tagcctccca
     2461 gggaaaaacg gttgcgggat ataaacccgt agcgaagggg agcaaagaga cacccgaagg
     2521 gctgcgtaat aaagatgccc tggtgttgca gagtgtttca accatcgaac tgccttatga
     2581 agcagttaat cctatcgcgt taagcgaaga agaaagtagc gtggcgcaca gttgcccaat
     2641 caattacacc ctcatttcaa acggcctggc aaacctgacc gaaaaagtcg atcatgtcgt
     2701 ggtagaaggg actggcggct ggcgcagtct gatgaatgat ttgcgtccac tctctgaatg
     2761 ggtagtgcag gaacaactgc cggtgttgat ggttgtcggt attcaggaag gttgcattaa
     2821 ccatgcactg ctaacagctc aggcgatcgc caacgacggg ctgccgctca ttggctgggt
     2881 ggctaaccga atcaacccag gactggcgca ttatgcggaa atcattgatg tgctgggtaa
     2941 aaaacttccg gcaccgctca ttggtgaact gccttatctg ccgcgcgccg aacagcgtga
     3001 actggggcaa tacatccgct tagctatgct gcgcagtgtg ctggcggtag atagagtcac
     3061 ggtgtaacgt ccgcgaaatt accgacgcaa ttacgcaggc aatcaataaa ccggggagta
     3121 gctgatactc cccggtcatt tcacatatca tcaacgtcga cataatcggc gcgtgcgtgg
     3181 tcgccgccaa cagtgtcgcc atcccggtca atccgagtaa aagtgtaatt tcttcgccat
     3241 cagggaacca taatcccagg ctacgaccat acaacatgcc aatggcaaga ccgataaata
     3301 gcgtcggtgt aaagacccca ccgggtgcgc cggaaccgct actcgccagc acggcacaca
     3361 gtttacaaag gaagatcccg gcaatgatca ttaacagtgg tggggcggtt aaaaaggatt
     3421 gtacggtgct atagccgttg ccccacactg caggtgtgaa cagggaaagc agacccacga
     3481 tcaacccgcc tagtgccagt tgccagggcg gcgcaagttt gagactcaca aatccacgat
     3541 gacaggcgtt cattaacgtt aacaacagtg gtccgcacag acctgccagc acacctgtac
     3601 tgataatcag cgcatagtca cgagcctgaa ccgtcactga gagttgtacg ttgtagagta
     3661 acgcgtcgct atgattaatc agattgctaa ccagcaatgc cacgacggcg gaaataatca
     3721 ccgggccgag agaggccaac atcatagtgc caaacagcac ttcggctata aataaactgc
     3781 cagcaagcgg ggcacgatag gccgcagcca ttcccgccgc ggccccacag gcgatccata
     3841 atttccactc ctggcgtggc gtaaaacgtt gggcaaaaca ggaggcggca agggcagcta
     3901 aaagaatcat cgcaccttcg cgaccaattg cactgccgct ggttactacc agcagagagg
     3961 caagcgattt aaccaggctt gctgcgtaat cgaactgtcc atcggtttgc aacgcttcca
     4021 tataatcggt cggcgcatga gggcgttgtt gggtaaattt ctgccagccc atcagcaaca
     4081 aacccgccgc cagtccgccg agcgccggag ttagcaaccg tcgccagggg gaaaggtttg
     4141 tcgctgcatt gaccagactg ccggagtcat tattgaggaa caaccactcc agtagcagca
     4201 tcgcatgacg aaacccggca acggcaaagg ccgcgagaat accgacgact gttgcgataa
     4261 gcagacggcg gaacatagtg cgcagatccg gatagatgtg tagatgatgc atgagcagaa
     4321 atgggcaatg aaacacgggc gactattttg cggcaaaaga ggccagccgc aaaagcagtg
     4381 cgtgctttaa gagataaaaa aacgtgacgc tgtaacctat tattgccgga ttgcgcgtaa
     4441 tcgtcaccat ccggcaatat tacggtgatc ctatcgaaac agcggtttaa ccgcgacagg
     4501 aattaacagt tgtgattgcc attgcgccag cgttaagcga gccagttcac ccagtgcacg
     4561 gtagaaaggg tgttctgctt tttcgataaa aacatcaaga aaacgtgttg accacggaaa
     4621 aaggtgccat gccagcaatt cttcgcattc tgtctggcga ccattctccg ccaaccacgc
     4681 agccatcaac agcagtgaac caaaatgatc ttccggttcg ttttgcttca tttcaaactg
     4741 aatgcctttc tcgcgcatcc actgacgaag tgccaatgtt gaatcgccaa acagcacaga
     4801 ttcgcgatcc agccagaccg acccccacgg cggagacggc agtgcccacg ggccgacaaa
     4861 caaacgctgc caggcctggg cgtgagtctc ttcacactgt gtctgaaaag ccgtcaccag
     4921 cggcgctaat gacgcttctg gtagaggcca ctgagtttcc cagccgtcac tggtgagtac
     4981 cgcaaccaga ggtgcggctt ccgcactctc tggagcgtaa taaaacagcg cgcccaacac
     5041 gcgcgccgcg acagaaaaat tatcttgctg tgaaaaatgg gtcattccta acatcctgaa
     5101 atgtgcgggt tgccccgcac caatttgtta acctgcaata gccattccta ctgtcatgtg
     5161 caggccataa aagagcacac gcccgatcat ctcaccgcca agtatgagga ttagccccag
     5221 aataagtccg gcaacgtgag gttcacggcg acgaatgagc gggcaaagcc agcatccaag
     5281 acctgcgcat aacaatacca cacgccagac ctgtaaggag gcgtaatctg gtaccagtgc
     5341 gctggcttgt tgcacggatg agtgaataga cgccagagac aaaccttgca gcacaatcac
     5401 cccggcacaa gcgatcagcg ccagaacgct aatgatggca aatggtgtgg tattaaatgt
     5461 aacgcgagct gcccgcagaa ttgcggcagc aagtattgga ccgctcaaca ataccgtcag
     5521 gaagaaagcc agcgtagtgt aaccgttatg ccaggttggc acggtgtcga tttgatacac
     5581 gcaggtcatc atccagacga aaatgacgcc gagcgccatg ctgaaaagta accagagttt
     5641 ccccaacgct tgcggcattt taccgatgac tgccaccagc caccataatc cgccaacggc
     5701 aaaaaatatg gaaccggcag caatctcgtt actcagacca gaagctccga ttcgattcag
     5761 cgagttaaac gcccgcagtg gcgatcccag gtgcatgaca gaggcaataa acccgacgcc
     5821 catcaacagc cagaggaaaa acatgccacg gacaatacgc tgacggtctg cgtcattttt
     5881 ggcggcgaac cagccaattc cgctaacaat cagcgcgcct actacgcatt gacccaatac
     5941 ggtaaagata accagtggcc actcatgcca tccatttccc attttacact tcctccggat
     6001 tagccagata accagtggta tcgccggtcg ggcggctgtt ggcgttaggt ttgataacga
     6061 tattgggttt tgtgaaatgc gcgcgcggca gtggcgcgac ggcagcaaga gtgccgtgct
     6121 tctggcgcag ctcttcaatt ggaccgaact caagtgcacg cagcgggcag gattcgacac
     6181 atatgggttg tttcccctcg gcgacgcgcg aataacaacc atcgcacttc gtcatgtgcc
     6241 ctttttcagc attgtactgt ggcgcgccgt acggacaagc catgtggcag tagcggcagc
     6301 cgatacaaac atcttcatca accaccacaa agccatcttc acgcttatgc attgcgccgc
     6361 tggggcagac ttttgtacat gcggggtcat cgcaatggtt acaggagatg gagagataat
     6421 aagcgaacac gttctggtgc cagacgccat tatcttcctg ccagtcgccg ccagcgtatt
     6481 cataaatacg gcggaaactg acttccgggc caagatcttt aaaatctttg cacgccagtt
     6541 cgcaggtttt acagccagta cagcggctgg aatcgataaa aaatccatat tgtgtggtca
     6601 tgggctactc cttaaacctt ttcgatctgg acaagattgc tgtgcgacgg gtttcccttt
     6661 gccagcggtg aagggcggtg agaggtcaga atattgatac tgccgccgtg atcgacccgg
     6721 tcaccaaaca tatccgcttt aagccacgca ccttgcccga tggcggtaac gccaggcaga
     6781 atacgcggag tcacttttgc ggcaatcagc atttctccat tattgttaaa tacccgcacg
     6841 gtatcgccat gacggatacc gcgtgcctga gcatcaatgg ggttgatcca cacctcttgt
     6901 gggcaggcct gctgtaacac atcaatattg ccgtagctgg agtgggtacg cgctttgtaa
     6961 tggaagcccg ttaactgcag tggataggtt ttccgcaggg gatcgtccca gccatcaaaa
     7021 cctggggtat acgcaggaag gggatgaata atttcatctt ttttcaattc ccaggtatct
     7081 gcaatcttcg ccagtcgttc agaataaatt tcgattttcc ccgaaggtgt tttcaacggg
     7141 tttgcctgtg gatcttcacg gaatgcgcgg aaagcgacgt agtgttcttc cgggcatttt
     7201 ttcttaaaga tcccggtcgt tttcatctcc tcgtagtcgg gcatctcagg gttacgttcc
     7261 ttcgttttcg catggagata tttgatccat tcatgctgac tgcgaccttc agtaaaggtt
     7321 tgataaacgt ctggtcctaa gcgtttggcg acttcactca gcatccagta gatgggtttg
     7381 cgttcaaatt ttgctgaggt tgcgggttgg gcgaggatca catagcccat attccctgca
     7441 gattcatgag agataaggtc ttcttgctct gttggcatca ggtcgggcaa caggatatcg
     7501 caatacttag ccgaggccgt catgaagtgg tcaatgccaa caatcatctc gcacttgctg
     7561 tcatcctgaa gcacctcatg ggtgtgattg atgtcgccat gttgattgat caatgtgtta
     7621 ctggcgtagc accataaaaa cttgatgggg acatccagtt tttcttttcc acgaacacca
     7681 tcacgggtcg cggtcatttc cgtaccatgg tcgatggcat ctgtccatgt aaagacggaa
     7741 atctgcgttt taacaggatt ctcgagcatc gggaaccatt ctacccccag atcccagcta
     7801 ccttcgcgta cgcctgagtt gccgccgttt atgccgacgt tgccggtgag aacggaaagc
     7861 atggcaatag cgcgggatgt ttgctcgccg ttggaatgtc gttgtggccc ccaaccctga
     7921 caaatataag caggttttgc tgaaccgatc tctcgtgcca actggataat tttttctgcc
     7981 gggatgctgg tgatttttgc tgcccattcc ggcgttttag ctatgccgtc aggcccttcg
     8041 cccagaatat aggctttata atgcgcgtta cgtggtgcgt tggcgggcag cgttttttca
     8101 tcgtaaccaa cacaatattt gtcgagaaat ggctgatcga ccatgttttc agtaatcagt
     8161 acccaggcaa tcgcacaggc cagtgcgcca tcggtgccag ggcgaatggg cagccattca
     8221 tcttcacgcc cggcagcagt gtcgttataa cgtggatcga tgacgatcat gcgtgcgttt
     8281 gaacgttcgc gggcttgctc gacgtagtaa gtgacaccac cgccgctcat ccgcgtttct
     8341 gccgggttat ttccgaacat aacgaccagt ttcgtattgg cgatatcatc cgggctgttg
     8401 ccatcattgg caccgaacat ataactcatt gcggcactga tctgtgcggt actgtagctg
     8461 ccatagcgac tgagaaaacc accgcaagag ttcatcagac ggtacgggac gtttgagttg
     8521 gtgatgtttc cgccatctac gcctgttccg tacaggacat gtacagcctc attgccgtaa
     8581 tctttcagga tccgccgaag attatcactg atggtatcca gggcttcgtc ccaacttatc
     8641 cgttcaaatt taccttcacc gcgcttgccg acgcgcttca tgggatattt caacctatca
     8701 ggatgattca tccgtcggcg gatagagcgc ccgcgtaaac acgctcgaac ctgatgatta
     8761 ccgtagacgt cgtcacctgt cgtatcagac tccacccagt acacggtgtc atctttcaca
     8821 tgcaaacgta acagacagcg gctcccgcag ttaacggtgc aggaactcca gaccgctttc
     8881 tcttctaccg gagcctctgc cgcccggacc atttgggaaa atggcagagt gaaagcactg
     8941 cttgccagcg caagactgcc aagtgcggag gttttcatca gacttctacg gctgatttca
     9001 gccttcatga gcgcctctgt ggtatggatt ttcatcatta ctcacttatt gcttttcaaa
     9061 caaaatgtca tgccagaatt tatggttgtc gtgggttata ttttttcgat ctcgaccaga
     9121 ttagtgtgct gcgggtttcc cttcgccagt ggtgaagggc gcagagtggt tagcgtattc
     9181 acacagccgc catggtcgat tttatcgcca gacatattgg cctcgtgcca ggctccctgg
     9241 cccatagcgc taactccagg gagaatacgt ggtgttactt tggctggtag ccgaacttcg
     9301 ccacgatggt taaacacccg caccatatcg ccgttggcaa tcccacgttt ctgcgcatct
     9361 atagggttga tccacacctc ctgacggcag gcagccttca ggagatcaat attgccgtag
     9421 gtcgagtgag tacgggattt gtaatggaaa ccaaacagtt gcagtgggaa ggttctacgt
     9481 tcaggggagt tccagccttc aaaggttgag gcataaactg gcaatgggct tatcacttca
     9541 tctttttcca gttcccaggt acgggcaatt tccgccagcc tgctggaata aatttcaatc
     9601 ttaccggaag gcgttttaag tggatttgcc tcggggtcgt cacgaaatgc tttgtaggcg
     9661 acaaaatggc cattgggatc tttacgctta tagataccca tttttttcag ttcgtcgtaa
     9721 gacggtaacg ccggatcttt ggcaagcatt ttggcgtaca gatgttgtaa ccattgttcc
     9781 tgcgtgcgac cttctgtgaa cttttgatag acgtcaggtc caagacgttt cgcgacttca
     9841 ctcaggatcc agtaaatcgg tttgcgttcg aatttttcgc tggtgacagg ctggaggaaa
     9901 atgagatatc ccatgttacc ggcgtagtcg ttaggaataa tatcttcctg ctcaacggtc
     9961 atcaggtctg gcagcagaat gtcggcatat tttgccgatg aggtcataaa gttttcgatg
    10021 accacaatca tttcgcattt cgattcgtcc tgcagaattt catgcgtttt gttgatgtca
    10081 gaatgctgat taacgagggt atttcccgcg tagttccaga tgaacttaat gggcacatcc
    10141 agtttatctt tgccgcggac gccgtcgcgg attgccgtca tttgcggacc atgatcgata
    10201 gcatctgtcc agctgaagca ggagattgac gttttgaccg gattatccag caccggcagg
    10261 cgttctatgg taatggtata ggtcgattca cgcgcgccac tatttccgcc gctgatgccg
    10321 acattgcccg tcaaaatagg taacatagca atagcgcgtg cagtcagttc gccgtttgcc
    10381 tggcgttgtg gcccccagcc ctggcagata taagcgggtt ttgctgtgcc aatttcacgc
    10441 gccagtttga tgatacggtc ctccgggata ccggtaattt gcgaagccca ctgcggcgtt
    10501 ttcgctgttt tatcgtcacc ttcaccaaga atataggctt tatagtgacc atttttgggt
    10561 gcatctgcgg gtaaggtttt ttcgtcatag ccgacgcagt atttatcgag aaaaggttga
    10621 tcaacgagat tttcgttaat caatacccag gcaatacccg caaccagcgc ggcatcggtg
    10681 cccgggcgaa tagggagcca ttcgtcttca cgaccggcag ccgtatcggt atatcgcgga
    10741 tcgataacaa tcattttggc gttcgatttc tcgcgcgctt tttcaagaag ataagtgatg
    10801 ccaccaccgc tcatgcgggt ttctgccggg ttgttaccaa acatcacgac cagcttgctg
    10861 ttttcaatat ccgtggtgct gttgccatca ttactgccgt aggtgtaggg catggcacag
    10921 gaaatttgcg cagtgctgta ggagccatac tggttgagtg aaccgccgta gcagttcatc
    10981 aggcgtttga ccgccgaggc tgatggcgaa gagcgggtca tattgccgcc aacgatcccc
    11041 gaagagtact gaatatatac agcctcattg ccatattgtt cgacggtttt cttcaggcta
    11101 ctggcgatag tatccagggc ttcatcccag ctaatccgtt cgaatttgcc ttcgccgcgt
    11161 ttgcccacgc gtttcattgg gtaattcaag cgatcgggat gattaatacg ccggcggatg
    11221 gagcgaccgc gcaaacaggc gcgtacctga tggttgccgt actcatcgct gccggtattg
    11281 tcagtttcca cccaggtcac ttcattatct ttaacatgta gacgaagtgc acagcggcta
    11341 ccacagttga cggaacaggc accccagacc actttttcgc gggcctgttg taccgctgct
    11401 gctgcattgc gcagggtaaa cggcaaagaa aaaccgcctg cagccagcgc cagagaacct
    11461 atcgcggtag atttaacgag tgttctgcgg ctgatgccca ccattcgttc atttttggac
    11521 ataactcact ccctg
//
LOCUS       DAPOAV010000114        11397 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.114, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000114 DAPOAV010000000
VERSION     DAPOAV010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11397
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.114"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            200..1771
                     /gene="garD"
                     /locus_tag="RN951_003846"
     CDS             200..1771
                     /gene="garD"
                     /locus_tag="RN951_003846"
                     /EC_number="4.2.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate dehydratase"
                     /protein_id="HDX2528775.1"
                     /translation="MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLE
                     LIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTL
                     PLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDL
                     LPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKL
                     QPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQIAERHLQKLNQRQRET
                     CPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTP
                     RAVNEEIGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGK
                     SAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVP
                     VIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQW
                     GLHNQLAVFNPAPVT"
     gene            1920..2255
                     /gene="prlF"
                     /locus_tag="RN951_003847"
     CDS             1920..2255
                     /gene="prlF"
                     /locus_tag="RN951_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PrlF"
                     /protein_id="HDX2528776.1"
                     /translation="MPANARSHAVLTTESKVTIRGQTTIPAPVREALKLKPGQDSIHY
                     EILPGGQVFMCRLGDEQEDHTMNAFLRFLDADIQNNPQKTRPFNIQQGKKLVAGMDVN
                     IDDEIGDDE"
     gene            2255..2719
                     /gene="yhaV"
                     /locus_tag="RN951_003848"
     CDS             2255..2719
                     /gene="yhaV"
                     /locus_tag="RN951_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system ribonuclease
                     toxin YhaV"
                     /protein_id="HDX2528777.1"
                     /translation="MDFPQRVNGWALYAHPCFQETYDALVAEVETLKGKVPENYQRKA
                     ATKLLAVVHKVIEEHITVNPSSPAFRHGKSLGSGKNKDWSRVKFGAGRYRLFFRYSEK
                     EKVIILGWMNDENTLRTYGKKTDAYTVFSKMLKRGHPPADWETLTRETEETH"
     gene            complement(2774..3583)
                     /gene="agaR"
                     /locus_tag="RN951_003849"
     CDS             complement(2774..3583)
                     /gene="agaR"
                     /locus_tag="RN951_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aga operon transcriptional regulator AgaR"
                     /protein_id="HDX2528778.1"
                     /translation="MSNTDASGEKRVTGTSERREQIIQRLRQQGSVQVNDLSALYGVS
                     TVTIRNDLAFLEKQGIAVRAYGGALICDSTTPSVEPSVEDKSALNTAMKRSVAKAAVE
                     LIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLR
                     RQSQSFYGDQAEQSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERII
                     VVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPADSLEGLRKAGVEVILVGE"
     gene            3832..5112
                     /gene="kbaZ"
                     /locus_tag="RN951_003850"
     CDS             3832..5112
                     /gene="kbaZ"
                     /locus_tag="RN951_003850"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit KbaZ"
                     /protein_id="HDX2528779.1"
                     /translation="MKHLTEMVRQHKAGKTNGIYAVCSAHPLVLEAAIRYASANQTPL
                     LIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNFPQDALILGGDHLGPNRWQNLPA
                     AQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCL
                     EHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWP
                     RIIALVVQPGVEFDHTNVIDYQPAKASALSQMVENYETLIFEAHSTDYQTPQSLRQLV
                     IDHFAILKVGPALTFALREALFSLAAIEEELVPAKACSGLRQVLEDVMLDRPEYWQSH
                     YHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQY
                     VKVRSGELQPTPRELIINHIQDILAQYHTACEGQ"
     gene            5135..5608
                     /gene="agaV"
                     /locus_tag="RN951_003851"
     CDS             5135..5608
                     /gene="agaV"
                     /locus_tag="RN951_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417602.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIB"
                     /protein_id="HDX2528780.1"
                     /translation="MPNIVLSRIDERLIHGQVGVQWVGFAGANLVLVANDEVAEDPVQ
                     QNLMEMVLAEGIAVRFWTLQKVIDNIHRAADRQKILLVCKTPADFLTLVKGGVPVNRI
                     NVGNMHYANGKQQIAKTVSVDAGDIAAFNDLKTAGVECFVQGVPTEPAVDLFKLL"
     gene            5619..6398
                     /locus_tag="RN951_003852"
     CDS             5619..6398
                     /locus_tag="RN951_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HDX2528781.1"
                     /translation="MEISLLQAFALGIIAFIAGLDMFNGLTHMHRPVVLGPLVGLVLG
                     DLHTGILTGGTLELVWMGLAPLAGAQPPNVIIGTIVGTAFAITTGVKPDVAVGVAVPF
                     AVAVQMGITFLFSVMSGVMSRCDRMAENADTRGIERVNYLALLALGIFYFLCAFLPIY
                     FGAEHAKTIIDVLPQRLIDGLGVAGGIMPAIGFAVLLKIMMKNVYIPYFILGFVAAAW
                     LKLPVLAIAAAALAMALIDLLRKSPEPTQPAAQKEEFEDGI"
     gene            6388..7266
                     /locus_tag="RN951_003853"
     CDS             6388..7266
                     /locus_tag="RN951_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019079236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HDX2528782.1"
                     /translation="MASNQTTLPNVSENEETLLTGVNENVYEDQSIGAELTKKDINRV
                     AWRSMLLQASFNYERMQASGWLYGLLPALKKIHTNKRDLARAMKGHMGFFNTHPFLVT
                     FVIGIILAMERSKQDVNSIQSTKIAVGAPLGGIGDAMFWLTLLPICGGIGASLALQGS
                     ILGAVVFIVLFNVVHLGLRFGLAHYAYRMGVAAIPLIKANTKKVGHAASIVGMTVIGA
                     LVATYVRLSTTLEITAGDAVVKLQADVIDKLMPAFLPLVYTLTMFWLVRRGWSPLRLI
                     AVTVVLGIVGKFCHFL"
     gene            7284..7718
                     /locus_tag="RN951_003854"
     CDS             7284..7718
                     /locus_tag="RN951_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDX2528783.1"
                     /translation="MLSIILTGHGGFASGMEKAMKQILGEQSQFIAIDFPETSSTALL
                     TSQLEEAIAQLDCEDGIVFLTDLLGGTPFRVASTLAMQKPGCEVITGTNLQLLLEMVL
                     EREGLSGEEFRVQALECGHRGLTSLVDELGRCHEECPVEEGI"
     gene            7715..8848
                     /gene="nagA"
                     /locus_tag="RN951_003855"
     CDS             7715..8848
                     /gene="nagA"
                     /locus_tag="RN951_003855"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDX2528784.1"
                     /translation="MTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPAGVTERDA
                     ELLCPAYIDTHVHGGAGVDVMDDAPDVLDKLAMHKAREGVGSWLPTTVTTPLNTIHAA
                     LKRIAQRCQRGGPGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQLIAVSQHT
                     LRVVALAPEKEGALQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMT
                     GLHHREPGMVGAGLTDKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGM
                     PDGRYTLCGEEVQMHGGVVRTASGGLAGSTLSVDAAVRNMVELTGVTPAEAIHMASLH
                     PARMLGVDGVLGSLKPGKRASVVALDSGLHVQQIWIQGQLASF"
     gene            9199..10353
                     /locus_tag="RN951_003856"
     CDS             9199..10353
                     /locus_tag="RN951_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AgaS family sugar isomerase"
                     /protein_id="HDX2528785.1"
                     /translation="MPENYTPAAAATGTWTEEEIRHQPRAWIRSLTNIDALRSALNNF
                     LEPLLRKENLRIILTGAGTSAFIGDIIAPWLASHTGKNFSAVPTTDLVTNPMDYLNPA
                     HPLLLISFGRSGNSPESVAAVELANQFVPECYHLPITCNEAGALYQNAINSDNAFALL
                     MPAETHDRGFAMTSSITTMMASCLAVFAPETINSQTFRDVADRCQAILTSLGDFSEGV
                     FGYAPWKRIVYLGSGGLQGAARESALKVLELTAGKLAAFYDSPTGFRHGPKSLVDDET
                     LVVVFVSSHPYTRQYDLDLLAELRRDNQAMRVIAIAAESSDIVAAGPHIILPPSRHFI
                     DVEQAFCFLMYAQTFALMQSLHMGNTPDTPSASGTVNRVVQGVIIHPWQA"
     gene            10366..11226
                     /gene="kbaY"
                     /locus_tag="RN951_003857"
     CDS             10366..11226
                     /gene="kbaY"
                     /locus_tag="RN951_003857"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit KbaY"
                     /protein_id="HDX2528786.1"
                     /translation="MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSP
                     VILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRRKVHAGVRSAM
                     IDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEA
                     KRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFV
                     RRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKIN
                     VCGSANRISA"
BASE COUNT         2754 a         2918 c         3006 g         2719 t
ORIGIN      
        1 tatgcacata aggttgcgcg ctaaagcaca gatttgcgct ttaccttacc gggcggcact
       61 gcaatccctg aaatgattga cattgatcac atttctgcgt ttaaactcct gacattctta
      121 tttcacccaa tgaagtcatt tatttttaaa tgagaccagg tcctcatttt aataacccct
      181 ggctggagaa tattgcacaa tggccaacat cgaaatcaga caagaaacgc caactgcgtt
      241 ttatataaaa gttcacgaca cagataatgt ggcaattatt gttaatgata atggcctgaa
      301 agcaggaacg cgttttccgg atgggctgga attaattgaa catattcccc aggggcataa
      361 agtcgcattg ctggacattc cggctaatgg tgaaattatt cgttatggcg aagtgattgg
      421 ttacgccgtg cgtgcaatcc cacgcggaag ctggatcgac gaatcaatgg ttgtactacc
      481 ggaagcgccg ccgttacaca cgctgccact ggcaaccaaa gtcccggaac ccttaccgcc
      541 gctggaagga tacacctttg agggctatcg caatgccgat ggcagcgtgg gcaccaaaaa
      601 cctgctcggt atcaccacca gcgtccactg tgtggcaggc gtggtggact atgtagtaaa
      661 aatcattgaa cgcgatctgc taccgaaata cccgaacgtc gatggcgtgg tggggctgaa
      721 tcatttgtac ggttgtggcg tggcgattaa cgcaccggcg gcagttgtac ctatccgtac
      781 cattcacaat atttcgctga atcctaactt tggcggcgaa gtaatggtga ttggcctggg
      841 ttgtgaaaag ttgcagcctg agcgcctgct gactggaacg gatgatgtgc aagctattcc
      901 agtagaaagc gccagcattg tcagtttgca ggatgaaaag catgtcggtt ttcagtccat
      961 ggtcgaggat attttgcaga tcgccgaacg ccatctacaa aaactgaatc aacggcagcg
     1021 agaaacctgc ccggcttcag aactggtcgt tggtatgcag tgcggtggca gcgatgcgtt
     1081 ttctggtgta acggcaaacc cggcggttgg ctatgcgtct gatctactgg tgcgctgcgg
     1141 cgcaacggtg atgttttcag aagtaacgga agtgcgtgac gcgatccatc tgctgacacc
     1201 acgcgcagtg aacgaagaga tcggcaaacg gctgctggag gagatggagt ggtacgataa
     1261 ctatctcaat atgggaaaaa ccgaccgcag cgccaaccct tcgccgggca acaagaaagg
     1321 cggtctggca aacgtggtag agaaggcact cggctccatt gctaaatcgg gtaaaagcgc
     1381 aattgttgaa gtgctgtcgc ccggtcaacg cccgactaaa cgcggattaa tttacgccgc
     1441 gacgccagcc agcgattttg tctgtggcac gcaacaggtg gcttcgggta tcacagtgca
     1501 agtgtttacg accggtcgtg gtacgccgta cggcctgatg gcggtacccg tcattaaaat
     1561 ggcaacccgc accgagctgg cgaaccgctg gtttgattta atggatatta atgcgggcac
     1621 catcgctacc ggcgaagaaa ctattgaaga ggtgggctgg aagttgttcc actttattct
     1681 cgacgtcgcc agcgggaaga agaaaacctt ctcggatcaa tgggggctgc ataaccagct
     1741 ggcggtgttt aacccggcac cggtgacctg atttcttttg gaacgtccct cgcaaaacat
     1801 ggccttagtg ccatgttttt attgtttaaa gcccccacgt ccattaataa tgcatttgca
     1861 ttaccttagt tcaagcttat aatttgagca gaaaacaggc tgtaaaagga cagtgaatca
     1921 tgcccgctaa tgctcgctct cacgctgtac tgaccactga atcaaaggtc acgatacgcg
     1981 gacaaacaac tatccccgcg ccagtgcgtg aggccttaaa actgaagcca ggccaggaca
     2041 gcattcatta cgaaattctg cctggtgggc aagtatttat gtgccgactg ggagatgaac
     2101 aggaggatca tactatgaat gcatttttgc gttttctgga tgcagatatc cagaacaacc
     2161 cgcaaaaaac tcgtccattc aacattcaac aaggaaagaa acttgtcgct ggcatggacg
     2221 tcaacattga tgatgagatt ggcgacgacg aataatggat tttccacaaa gggttaatgg
     2281 ttgggcgcta tatgctcatc cctgttttca ggaaacctac gacgctttag ttgccgaagt
     2341 cgagacatta aagggaaaag ttcctgaaaa ttatcagaga aaagccgcca caaagttatt
     2401 ggcggtagtc cataaagtga ttgaggagca tatcacggtc aatccatcat caccggcatt
     2461 ccgtcatggc aagtcgttag gctctgggaa aaataaagac tggtcacggg taaaatttgg
     2521 tgctggtcgt tatcgtctct tctttcgtta tagtgaaaaa gagaaagtca tcattctggg
     2581 atggatgaac gatgaaaaca ctctgcgcac ctacggtaaa aaaacagatg cctataccgt
     2641 attcagcaaa atgttaaaaa gaggacatcc tcctgccgac tgggaaaccc tcacccgaga
     2701 aacagaagaa acccattgat ggtgttcaca atgcccgccg aacgcattcg tgttgaccag
     2761 cgggcatcct ttctcactcc ccgaccagaa tcacttcaac cccagccttt cgcagtcctt
     2821 ccaggctatc cgcaggaatg ccttcatcaa caatgatcat gtcgatacgt tgagtatcaa
     2881 tgatcttatg taaactggaa cgattgaact tactggaatc ggtgaccacg atgatccgtt
     2941 ccgcaacttc gcacatccga cggtttaaac gagcttcatc ttcattatgt gtgctgacgc
     3001 cgcgctccag atcgatcgca tctacaccaa gaaacagcat atcgaagtgg taattttgca
     3061 gcgattgctc agcctgatcg ccgtaaaaag attgcgactg acggcgcaaa tgcccgccgg
     3121 tcatcagcag ctcaacgcct tccgcttcca gcaacgcatt agccacgttc ataccgttgg
     3181 tcatcgcaat tacgtcagtg tgcttgcgca tcagacgagc aatctcaaaa gtggtggtcc
     3241 cggaatcgag gataacccga tgacctggct gaatcaactc aacggcagct ttcgcaacgc
     3301 tgcgtttcat cgcggtgttc agtgcgcttt tatcttccac tgatggctcg actgacggcg
     3361 tcgtgctatc gcagatcaac gcgccaccat aggcacgcac agcgatcccc tgcttttcca
     3421 gaaacgccag atcgttgcgg atcgtcacag tagatacgcc atacaatgcc gacagatcgt
     3481 taacctgcac actcccttgc tgtcgcagac gctgaatgat ctgttctcgt cgctcgctgg
     3541 tgccagtcac tcgcttctca cctgaagcgt cggtattact catagtaagt cctttcgtaa
     3601 aactttcgtt tcatttcgtt ttgcctatta acgcctttct attaagcaaa tgcaagccca
     3661 ccttgcccat tgacgcaagc tactctcgtt tcagtgactt tcattatgtt tcttttgtga
     3721 atcagatcag aaaactatta tctttcgttt tatttttatc tcaccatgac gcagtatcaa
     3781 ctgaaacaaa acgaaagatt aatatcgcag taatctgaac tggagaggaa agtgaaacat
     3841 ctgacagaaa tggtgagaca gcacaaagcg ggcaaaacaa atggaattta tgccgtttgt
     3901 tccgcacatc cgctggtgct ggaggctgca atccgctacg ccagtgcaaa ccaaacgccg
     3961 ttactgattg aagcaacctc caatcaggta gaccagttcg gcggttatac cggaatgacg
     4021 cccgccgatt ttcgcggctt tgtttgtcag ctcgccgact cgttgaattt cccgcaggat
     4081 gcgttgattc tgggtggtga ccatctgggg ccaaaccgct ggcaaaacct gccggccgct
     4141 caggcaatgg ccaatgccga tgatttgatt aaaagctacg ttgcggcagg attcaaaaaa
     4201 atccaccttg attgcagcat gtcctgtcag gacgatccga ttcccttaac tgatgacatc
     4261 gtggctgaac gcgccgcccg tctggcgaaa gtggcggaag aaacctgtct tgaacacttt
     4321 ggcgaagccg atctggagta tgtcattggt accgaagtgc cggtacctgg cggcgcgcat
     4381 gaaaccttaa gcgagctggc ggtcaccacg ccggatgccg cccgcgccac gctggaagcc
     4441 catcgtcacg cctttgaaaa gcaaggtttg aatgccatct ggccacgcat cattgccctg
     4501 gtggttcaac ccggcgtcga attcgatcac accaacgtta ttgattatca gcccgccaaa
     4561 gcgagcgcct taagccagat ggtcgaaaac tacgaaacgc tgattttcga agcgcactct
     4621 accgattatc aaacgccgca atcgctgcgc cagctggtga ttgaccactt tgccattctg
     4681 aaagttggcc cagcgctgac cttcgccctg cgtgaagctc tgttctctct ggcggcgatt
     4741 gaagaagaac tggtgccagc gaaagcctgt tctggtctgc gtcaggtgct ggaagacgtg
     4801 atgctcgacc gcccggaata ctggcaaagc cactaccacg gtgacggcaa cgcgcgtcgt
     4861 ctggcgcgtg gttatagcta ctcggatcgc gtgcgctatt actggccgga cagccagatt
     4921 gatgacgctt tcgctcatct ggtacgtaat ctggcggatt caccaattcc gctgccgctg
     4981 atcagccagt atctgccgct gcagtacgtg aaagttcgct ccggcgagct gcagccaacg
     5041 ccacgggaac tcattatcaa ccatattcag gacatcctgg cgcagtacca cacagcctgt
     5101 gaaggccaat aagcaaaaca aagaggaaca cgctatgcca aatattgttt taagccggat
     5161 tgatgaacgc ttgattcacg gtcaggtcgg cgttcaatgg gtcggatttg cgggggcaaa
     5221 tctggtgctg gtagccaacg atgaggttgc cgaagatccg gtacaacaaa acctgatgga
     5281 aatggtactg gcagaaggga tcgccgtacg tttctggacg ctgcaaaaag ttatcgacaa
     5341 cattcatcgc gccgccgatc gacagaaaat cctgctggtt tgtaaaacac ccgccgattt
     5401 cctgacgctg gtgaaaggtg gcgttccggt gaatcgcatt aacgttggca atatgcacta
     5461 cgccaatggc aaacaacaaa tcgccaaaac ggtttctgtg gatgcgggcg atatcgcagc
     5521 atttaacgac ctgaaaaccg ctggggtgga atgcttcgtt cagggcgtcc cgacagagcc
     5581 tgctgtggac ctctttaaat tactttgagg gattcatcat ggaaatcagc ctgttgcagg
     5641 catttgcgtt gggcattatc gcctttatcg ctggcctgga tatgtttaac ggcctaaccc
     5701 atatgcaccg cccggtggtc ctcggcccgt tggtcgggct ggtacttggc gatctgcata
     5761 ccggaatttt aaccggcggt acgctggaac tggtgtggat ggggctggcc ccgctggcgg
     5821 gcgcacagcc gcctaacgtg attatcggta ctatcgtcgg cacggcgttt gccattacta
     5881 ctggcgtgaa acccgatgtc gcagtaggtg tcgccgtacc tttcgctgtc gcagtacaga
     5941 tggggattac cttcctgttc tcggtgatgt ccggcgtgat gtctcgctgc gaccggatgg
     6001 cggagaacgc cgatactcgc ggcattgaac gcgtgaacta tctggcactg ctggcactcg
     6061 gcattttcta ttttctctgc gctttcctgc ctatctactt cggcgcggaa catgcaaaaa
     6121 ccatcattga tgtcctgccg caacgattaa tcgacggcct cggcgtcgcg ggcggcatca
     6181 tgccagcaat cggttttgcc gtgctgctga aaatcatgat gaaaaacgtc tacatcccct
     6241 acttcatcct gggctttgtt gccgccgcct ggctcaagtt accagtgctg gctattgctg
     6301 ccgctgcgct ggcgatggcg ctgatcgact tgctgcgtaa atctcctgaa ccgactcaac
     6361 ctgcggcaca gaaagaggaa tttgaagatg gcatctaatc aaaccaccct gccgaacgtc
     6421 agtgaaaacg aagaaacatt gctgactggc gtcaatgaaa acgtgtatga agatcagagc
     6481 attggcgcgg agctgacgaa aaaagatatc aaccgcgtcg cctggcgttc catgctgtta
     6541 caagcgtctt ttaactacga acgtatgcag gcttctggct ggttgtacgg tctgctgcct
     6601 gctctgaaaa agatccacac taataaacgc gacctggcgc gcgccatgaa ggggcatatg
     6661 ggtttcttca atacccatcc gtttctggtg acgtttgtta tcggcattat ccttgcgatg
     6721 gagcgttcta agcaggacgt taacagtatt cagagcacca aaattgccgt cggtgcgccg
     6781 cttggcggga ttggcgatgc aatgttctgg ctaacgctac tgccgatttg tggcgggatt
     6841 ggagccagtc tggcattgca aggctccatt cttggcgcag tcgtctttat tgtgctgttc
     6901 aacgtggtac acctggggct gcgttttggt ctggcgcatt atgcttaccg catgggcgtg
     6961 gcggcgattc cactgattaa agcgaatacc aaaaaagtcg gccatgctgc gtctatcgtt
     7021 gggatgacgg taatcggtgc gctggtggca acctatgttc gtttaagcac cacgctggaa
     7081 atcacggcgg gcgacgcagt ggttaagtta caggctgatg ttatcgacaa actgatgccg
     7141 gccttcttac cgttggtcta caccctgacc atgttttggt tggtacgccg cggctggagt
     7201 ccgctgcgtc tgattgcagt taccgtggtt ctcggcatcg tcggtaaatt ctgccatttc
     7261 ctttaaatac aatgaggtat tagatgttaa gtattatttt gacagggcat ggcgggtttg
     7321 ccagcggcat ggaaaaagca atgaagcaaa ttctcggtga gcaatcgcag tttatcgcca
     7381 tcgattttcc ggaaacctca agcaccgcgc tgcttacatc gcagcttgaa gaggccatcg
     7441 cccaactgga ttgtgaagac ggcattgttt ttctgacgga tttgctgggc ggcacgccgt
     7501 ttcgcgtagc ttcaacgctg gcgatgcaaa aaccgggctg tgaagtgatc accggcacca
     7561 atttgcaact gctactggag atggtgctgg agcgcgaagg gttaagcggt gaagaattcc
     7621 gtgtacaggc gctggagtgt ggacaccgag ggctgaccag tctggtggac gagttaggcc
     7681 gctgccatga agaatgtccg gtcgaggaag gaatatgaca cacgttctgc gcgccagaag
     7741 gctgctgact gaagagggat ggctcgatga ccatcagttg cgtattgctg acggtgtcat
     7801 cgcagcaatc gaaccgattc cagcgggcgt gactgaacgc gatgcggaac tgctctgccc
     7861 tgcttacatc gacacccatg tacacggtgg tgcgggcgtt gatgtaatgg atgacgcgcc
     7921 ggatgtactc gacaagctgg caatgcacaa ggcacgcgaa ggtgtcggca gttggttacc
     7981 gaccaccgta accacgccgc ttaataccat tcatgcggcg ctgaaacgta ttgctcaacg
     8041 ttgccaacgc ggcggacctg gtgcgcaagt gctggggagt tatctcgaag gaccgtactt
     8101 cacgccgcag aataaaggcg cgcatccgcc ggagttgttt cgcgagcttg aaattgccga
     8161 gctggatcag ttgattgccg tttctcagca caccttacgt gtggtagcgc tggcaccgga
     8221 aaaagaaggg gcattgcagg ccatccgcca tcttaaacag caaaacgtaa gggtgatgct
     8281 ggggcatagc gcggcgacct ggcaacaaac ccgcgccgca tttgatgctg gtgccgacgg
     8341 cctggtgcat tgctataacg ggatgacagg tttacatcac cgcgaaccgg gaatggttgg
     8401 cgcgggatta acggacaagc gcgcctggct ggaactgata gccgatggtc atcatgtgca
     8461 tccggcggca atgtcgctgt gttgttgctg tgcgaaagag agaatcgtac tgatcaccga
     8521 cgcgatgcag gcagctggga tgccggatgg tcgctatacg ttatgtggtg aagaagtgca
     8581 gatgcacggt ggcgttgtcc gtaccgcgtc tggtgggctg gcgggcagta cgctgtctgt
     8641 tgatgcggca gtgcgcaata tggtcgagtt gacgggcgta acgcctgcgg aagccatcca
     8701 tatggcgtcg ctgcatccgg cgcgaatgct gggtgttgat ggtgttctgg gatcgcttaa
     8761 accgggcaaa cgcgccagcg tcgttgcgct ggatagcggg ctacatgtgc aacaaatctg
     8821 gattcagggt caattagctt cgttttgata gtttgctcct ttattgggcc ttcacttccc
     8881 ccgtaaggcc tttctttttc tttcgttttg atctgtgcag cggtgtcgga tgcgacgcta
     8941 acgcgtctta tccgacctac agttggtgac cgcaaggccg gataaagcgt ttgcgccgca
     9001 tccagcaatc ccttttgctt cctttatctt ttctttcaac gatcacaaat ttcgttttat
     9061 ttcttttttc tccattgaac tttcagtttc ttttctatag attttaatca acgaaagaca
     9121 tcaccaagtg aaatgaaacg aaaggcaagt gaaagcgaca acgcccgacg tcaagttcat
     9181 cagactaagg attgagttat gccagaaaat tacacccctg ctgccgccgc aaccggtaca
     9241 tggactgaag aagagatccg ccatcagcct cgcgcatgga tccgttcact caccaacatc
     9301 gacgcgctac gttccgcgct caataacttc cttgaaccgt tactgcgcaa agagaatctg
     9361 cggatcatcc tgaccggagc cggaacgtcg gcatttatcg gtgacatcat cgcgccgtgg
     9421 ctcgccagcc ataccggtaa aaacttcagc gccgtaccga ccaccgatct ggtcaccaat
     9481 ccgatggact acctgaaccc agctcatccg ctgctgttga tctccttcgg tcgatccggc
     9541 aacagcccgg aaagcgtcgc agccgtggaa ctggcaaatc aatttgtacc ggaatgctat
     9601 cacctgccga tcacctgcaa cgaagcgggc gctctttacc aaaacgcgat caacagcgat
     9661 aacgcgtttg ccctgctgat gcccgcagaa acgcacgatc gcggctttgc gatgaccagc
     9721 agcattacca ccatgatggc cagctgcctc gcggttttcg cacctgagac gatcaacagc
     9781 caaaccttcc gcgacgtggc ggatcgttgc caggcgatcc tgacctcact gggcgatttc
     9841 agcgaaggtg tgtttggtta cgcaccgtgg aaacggatcg tttatctcgg tagcggtggc
     9901 ttacagggcg cagcacgcga gtcggcgctg aaagtgctgg aactgacggc gggtaaactg
     9961 gcggcctttt atgattctcc aaccggattc cgtcatggac caaaatcgct ggtcgatgac
    10021 gaaacgctgg tggtggtatt tgtctccagc cacccttaca cccgtcagta tgatcttgat
    10081 ctgctggctg aacttcgccg tgacaaccag gcaatgcgtg taatcgccat cgccgcggaa
    10141 agcagcgaca tcgtcgctgc cggtccacat atcatcctgc caccgtcacg tcactttatc
    10201 gacgttgagc aggcattttg cttcctgatg tacgcccaga cgtttgcact gatgcagtcg
    10261 ctgcacatgg gcaatacgcc ggatacccca tcagccagtg gcaccgttaa ccgcgtggtg
    10321 caaggcgtaa tcattcatcc gtggcaggca taagaggatc gcattatgag cattatctcc
    10381 actaaatatc tgttacagga cgcccaggcc aatggctacg cggtgcctgc ttttaacatt
    10441 cataacgccg agacgatcca agcgatcctc gaagtgtgca gtgaaatgcg atcgccggtg
    10501 atcctcgccg gaacgccggg gacctttaaa cacatcgcgc tggaagagat ctacgccctg
    10561 tgtagcgcct attccacaac ctacaacatg ccactggcgc tgcatctcga ccaccacgaa
    10621 tcgctggatg atattcgccg taaagtccac gcaggtgtgc gcagtgcgat gatcgacggc
    10681 agccacttcc cgtttgccga gaacgtgaag ctggtgaaat cggttgttga cttctgccac
    10741 tcacaagatt gcagcgtgga agcagaactg ggccgcctgg gcggtgttga agatgacatg
    10801 agcgttgacg ccgaaagtgc attcctgacc gatccacaag aagctaaacg ctttgtcgaa
    10861 ctgactggcg tcgacagcct ggcggtagcg attggtacgg cgcacggctt atacagcaaa
    10921 acgccgaaga ttgatttcca gcggctggcg gaaattcgtg aagtggtgga tgttcctctg
    10981 gtgctgcatg gtgccagcga tgttccggat gaatttgtcc gtcgcactat tgaacttggc
    11041 gtcacaaaag tgaacgttgc cacagaatta aaaatagcct tcgctggcgc ggttaaagcc
    11101 tggtttgcgg aaaatccgca gggtaatgat cctcgttatt atatgcgcgt cggaatggat
    11161 gcgatgaaag aagttgtcag aaataaaatt aatgtctgtg gttcagcgaa tcgaatttca
    11221 gcataatcat tagtttttta tgatttatcc caatgtactt cccgattaat atcggggagt
    11281 gccttaatgg aaaaggagat aactaaacct taataaatac atcactacaa tatcgcaaca
    11341 ataatatatt taaaaaaatt atattattca actttatggt gaggattaca caatgac
//
LOCUS       DAPOAV010000115        11388 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.115, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000115 DAPOAV010000000
VERSION     DAPOAV010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11388
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.115"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(107..1189)
                     /gene="lptG"
                     /locus_tag="RN951_003858"
     CDS             complement(107..1189)
                     /gene="lptG"
                     /locus_tag="RN951_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313266.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HDX2528787.1"
                     /translation="MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQ
                     GSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQV
                     ALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNF
                     VYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPK
                     QITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMW
                     SKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYG
                     IPPIIGALLPSASFFLISLWLLMRKS"
     gene            complement(1189..2289)
                     /gene="lptF"
                     /locus_tag="RN951_003859"
     CDS             complement(1189..2289)
                     /gene="lptF"
                     /locus_tag="RN951_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptF"
                     /protein_id="HDX2528788.1"
                     /translation="MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIP
                     ANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAA
                     MILAVFTAIVAAINVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLF
                     IESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTAL
                     LRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTV
                     FMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTV
                     NLIYLALAIVLNLWDTVPVRRLRASFSRKGAV"
     gene            2556..4067
                     /gene="pepA"
                     /locus_tag="RN951_003860"
     CDS             2556..4067
                     /gene="pepA"
                     /locus_tag="RN951_003860"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HDX2528789.1"
                     /translation="MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYIS
                     ALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLND
                     TGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
                     VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNV
                     ITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDS
                     GGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRP
                     GDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHI
                     TGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITA
                     GCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE"
     gene            4421..4864
                     /gene="holC"
                     /locus_tag="RN951_003861"
     CDS             4421..4864
                     /gene="holC"
                     /locus_tag="RN951_003861"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004098129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit chi"
                     /protein_id="HDX2528790.1"
                     /translation="MKNATFYLLDNDTTVDGLSAVEQLVCEIAAERWRSGKRVLIACE
                     DEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTS
                     FADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK"
     gene            4864..7719
                     /gene="valS"
                     /locus_tag="RN951_003862"
     CDS             4864..7719
                     /gene="valS"
                     /locus_tag="RN951_003862"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDX2528791.1"
                     /translation="MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNV
                     TGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTR
                     HDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRL
                     YKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLV
                     VATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCV
                     KITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQK
                     LERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKP
                     AVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRN
                     EDEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSG
                     FDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPL
                     DMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALAST
                     GRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFN
                     QTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLV
                     TVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTE
                     WLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVL
                     PADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEG
                     FVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL"
     gene            complement(7775..8971)
                     /locus_tag="RN951_003863"
     CDS             complement(7775..8971)
                     /locus_tag="RN951_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709944.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF898 domain-containing protein"
                     /protein_id="HDX2528792.1"
                     /translation="MAQVINEMDVPSHSFVFHGTGERYFLICVVNVLLTIITLGIYLP
                     WALMKCKRYLYANMEVNGQRFSYGITGGNVFVSCLVFVFFYFAILMTVSADMPLVGCV
                     LTLSLLVLLIFMAAKGLRYQALMTSLNGVRFSFNCSLKGFWWVTFFLPILMAIGMGAV
                     FFISTKMLHANSSSSVIISVVLMAIVGIVSIGIFNGTLYSLVMSFLWSNTSFGIHRFK
                     VKLDTTYCIKYAILAFLALLPFLAVAGYIIFDQILNAYDSSVYANDDIENLQQFMEMQ
                     RKMIIAQLIYYFGVAVSTSYLTVSLRNHFMSNLSLNDGRIRFRSTLTYHGMLYRMCAL
                     VVISGITGGLAYPLLKIWMIDWQAKNTYLLGDLDDLPLINKEEQPDKGFLARISRGIM
                     PSLPFL"
     gene            9156..9659
                     /locus_tag="RN951_003864"
     CDS             9156..9659
                     /locus_tag="RN951_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDX2528793.1"
                     /translation="MNNIAPQSPVMRRLTQQDNPAIARVIRQVSAEYGLTADKGYTVA
                     DPNLDELYQVYSQPGHAYWVVEFDGEVVGGGGIAPLAGSESDICELQKMYFLPAIRGK
                     GLAKKLALMAMEQAREMGFKRCYLETTAFLKEAIALYEHLGFEHIDYALGCTGHVDCE
                     VRMLREL"
     gene            complement(9705..10121)
                     /gene="rraB"
                     /locus_tag="RN951_003865"
     CDS             complement(9705..10121)
                     /gene="rraB"
                     /locus_tag="RN951_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E inhibitor RraB"
                     /protein_id="HDX2528794.1"
                     /translation="MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLE
                     TLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAE
                     KFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH"
     gene            10283..11287
                     /gene="argF"
                     /locus_tag="RN951_003866"
     CDS             10283..11287
                     /gene="argF"
                     /locus_tag="RN951_003866"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDX2528795.1"
                     /translation="MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLT
                     GKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYD
                     GIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLV
                     YAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTED
                     VAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNSKMMQLTGNPEVKFLHCLP
                     AFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSK
                     "
BASE COUNT         2992 a         2921 c         2883 g         2592 t
ORIGIN      
        1 accccactgc aatatattga attttaatta tttttcagga atgaacgaag cacactttgc
       61 taacaataat aaagggagct ttcgctccct ttattcgttc attcggttac gattttctca
      121 ttaacagcca caggctgatt aagaagaagc tggcgcttgg caacagtgcg ccgatgatcg
      181 gcgggatgcc ataaaccaac gtcagcgggc cgaagatctg gtccagtacg tagaagacaa
      241 aaccgaaact gataccggtg accacacgca cgcccatcgg tacgctacgc agtgggccaa
      301 agatgaacga cagcgccatc agcatcatca ccgccacaga tagcggctgg aagattttgc
      361 tccacatgtt gagctgataa cgtccggcat cctgaccgct cgacttcaga tacttcacat
      421 agttgtgcaa accgctgata gagagtgcat ccgggtccag cgccaccacg cccagtttgt
      481 caggcgtgag gttggttttc caggtgccgc tcaccgtctg cgaaccggta atctgtttcg
      541 gattggtcag atcagattca tcaacctgcg acagacgcca gactttatgt tccgggtcaa
      601 acttcgcagt agcggcatag cgtacggatt gcagacgacg attctcgtta aaggcataaa
      661 tactgatgcc acctaactct tcgtcacctt taacccgctc aatgtagacg aagttgttgc
      721 catctttcgc ccataaacct tgctgggtag agagcaacga gccgccgtac atcgcctgcg
      781 cacggtagtt acgcgccatc tgctcgccct gcggcgcgac ccattcgcca atcgccatcg
      841 tcagcaagac cagcggaatg gcggttttca ttaccgacag cgccacctgc atacgggtaa
      901 aaccagaagc ctgcatcacc accagttcgc tgcgctgcgc cagcatccca agaccaagca
      961 acgccccaag cagagccgcc atcgggaaga agatctgcac atctttcggc acgctcagca
     1021 aggtatacat tcctgcgcct aacgcgtcgt aactcccctg cccggctttt ttcagctgat
     1081 cgacaaactt gataatgccc gacagcgaca ccagcatgaa cagtgtcatc atgatggtgg
     1141 tgaaaatagt tttaccgata tagcggtcaa gtacgccaaa aggttgcatc acaccgctcc
     1201 tttacgcgaa aaactggcgc gcaggcggcg gaccggcacg gtgtcccaaa ggttgagaac
     1261 aatcgctaaa gccagataaa tcaggttaac ggtccacatc cacagcgtcg ggtccagctt
     1321 acctttaccg ccgttcgatt tcagggaggt ctggatcagg aagaaaagta gatacagcag
     1381 catggctggc agcatcgaca gtacgcgtcc ctgacgtggg ttaaccacgc tcagcggtac
     1441 gaccataagt gccatcataa acacggtgaa taccaacgtg atacgccagt tcagttctgc
     1501 gcgagcacga tcggtgtcag tgttccacaa tgtgcgcatg tccatctggt cggtatcgtt
     1561 cgggtcgagc gccaccgcct ggtgaccaat gatcgcctga taatcctgga aatccgtaat
     1621 gcggaaatca cgtaacagtg cagtgccttc gaagcgcgtt ccctggttga gagtgacgac
     1681 ctgggagccg tcgcgcagtt gggttaaatg tccggaatcg gccaccacca cagaaggacg
     1741 tgcattacct tttggtcgaa tttgcgcgag gaacacatct ttgaaatcgc tgccgtcaac
     1801 gctttcgatg aacagcaccg aactgccatt agtcgcttgc tggaattgcc cttgcgccag
     1861 cgccgccatg ccagggttcg ctttcgcttc tgctaacact tcatcctgat gacgcgatga
     1921 ccacggtccc gcccacatca cgttaatcgc cgcgacgatt gccgtgaata ccgcaaggat
     1981 cattgccgct ttcaccagaa ccgctttgct caggccgcag gcatgcatta ccgtaatttc
     2041 actttcggta tacagtttgc ccagcgtcat cagcagcccg aggaacaggc ttaatggcag
     2101 gataagctgc gccatttccg gcacgcccaa cccgagaagg gagagcacca gattcgccgg
     2161 aatatcgccg tcaaccgctg cgccgaggat cctcactaac ttttgacaga agaagatcaa
     2221 aagcaagatg aagagtatcg ccagctggct tttgagcgtc tcccgcacca gatatcttat
     2281 gattatcact ttaaatacgc ccgtaaaaac tcgtcttttg caggatttta gcttgtttca
     2341 tggcttaaac gtcatttatt ctcttgagtc gtcgaaatcg tcgctaagat aattatactc
     2401 aacggattca cctctcagat tttgttctga cgtgccaatg ccgtaataac gttaagatta
     2461 acacgaagtc atcgcaacag cggacatgag ttacgaaagc ttgcaattct atctgtagcc
     2521 accgccgttg tctttaagat tcaggagcgt agtgcatgga gtttagtgta aaaagcggta
     2581 gcccggagaa acagcggagt gcctgcatcg tcgtgggcgt cttcgaacca cgtcgccttt
     2641 ctccgattgc agaacagctc gataaaatca gcgatgggta catcagcgcc ctgctacgtc
     2701 ggggcgaact ggaaggaaaa ccggggcaga cattgttgct gcaccatgtt ccgaatgtac
     2761 tttccgagcg aattctcctt attggttgcg gcaaagaacg tgagctggat gagcgtcagt
     2821 acaagcaggt tattcagaaa accattaata cgctgaatga tactggctca atggaagcgg
     2881 tctgctttct gactgaactg cacgttaaag gccgtaataa ctactggaaa gtgcgtcagg
     2941 ctgtcgagac ggcaaaagag acgctctaca gtttcgatca gctgaaaacg aacaagagcg
     3001 aaccgcgtcg cccgctgcgt aaaatggtgt tcaacgtgcc gacccgccgt gaactgacca
     3061 gcggtgagcg cgcgatccag cacggtctgg cgattgccgc cgggattaaa gcagcgaaag
     3121 atctcggcaa tatgccgccg aatatctgta acgccgctta cctcgcttca caagcgcgcc
     3181 agctggctga cagctacagc aagaatgtta tcacccgcgt tatcggcgaa cagcagatga
     3241 aagagctggg gatgcattcc tatctggcgg tcggtcaggg ttcgcaaaac gaatcgctga
     3301 tgtcggtgat tgagtacaaa ggcaacgcgt cggaagatgc acgcccaatc gtgctggtgg
     3361 gtaaaggttt aaccttcgac tccggcggta tctcgatcaa gccttcagaa ggcatggatg
     3421 agatgaagta cgatatgtgc ggtgcggcag cggtttacgg cgtgatgcgg atggtcgcgg
     3481 agctacaact gccgattaac gttatcggcg tgttggcagg ctgcgaaaac atgcctggcg
     3541 ggcgtgccta tcgtccgggc gatgtgttaa ccaccatgtc cggtcaaacc gttgaagtgc
     3601 tgaataccga cgctgaaggc cgcctggtac tgtgcgacgt gttaacttac gttgagcgtt
     3661 ttgagccgga agcggtgatt gacgtggcga cgctgaccgg tgcctgcgtg atcgcgctgg
     3721 gtcatcacat taccggtctg atggcgaacc ataatccgct ggcccatgaa ctgattgccg
     3781 cgtctgaaca atccggtgac cgcgcatggc gcttaccgct gggtgacgag tatcaggaac
     3841 aactggagtc caattttgcc gatatggcga acattggcgg tcgtcctggt ggggcgatta
     3901 ccgcaggttg cttcctgtca cgctttaccc gtaagtacaa ctgggcgcac ctggatatcg
     3961 ccggtaccgc ctggcgttct ggtaaagcaa aaggcgccac cggtcgtccg gtagcgttgc
     4021 tggcacagtt cctgttaaac cgcgctgggt ttaacggcga agagtaattg cgtcaggcaa
     4081 ggctgttatt gccggatgcg gcgtgaacgc cttatccgac ctacacagca ctgaactcgt
     4141 aggcctgata agacgcgcaa gcgtcgcatc aggcaatgct gttattgtcg gatgcggcat
     4201 gaacgcctta tccgacctac acagcaccga actcgtaggc ctgataagac gtggcagcgt
     4261 cgcatcaggc aatgctgtta ttgtcggatg cggcgtgagc gccttatccg acctacacac
     4321 agcactgaac tcgtaggcct gataagacac aacagcgtcg catcaggcgc tgcggtgtat
     4381 acctgatgcg tatttaaatc caccacaaga agccccatat atgaaaaacg caacgttcta
     4441 ccttctggac aatgacacca ccgtcgatgg cttaagcgcc gttgagcagc tggtgtgtga
     4501 aattgccgca gaacgttggc gcagcggtaa gcgcgtgctc atcgcctgtg aagatgaaaa
     4561 gcaggcttac cggctggatg aagccctgtg ggcgcgtccg gcagaaagct ttgttccgca
     4621 taatttagcg ggagaaggac cgcgcggcgg tgcgccggtg gagatcgcct ggccgcaaaa
     4681 acgcagcagc agcccgcgcg atatattgat tagtctgcga acaagctttg cagattttgc
     4741 caccgctttc acagaagtgg tagacttcgt tccttatgaa gattctctga aacaactggc
     4801 gcgcgaacgc tataaagcct accgcgtggc tggtttcaac ctgaatacgg caacctggaa
     4861 ataatggaaa agacatataa cccacaagat atcgaacagc cgctttacga gcactgggaa
     4921 aagcagggct actttaagcc taatggcgat gaaagccagg aaagtttctg catcatgatc
     4981 ccgccgccga acgtcaccgg cagtttgcat atgggtcacg ccttccagca aaccatcatg
     5041 gataccatga tccgctatca gcgcatgcag ggcaaaaaca ccctgtggca ggtcggtact
     5101 gaccacgccg ggatcgctac ccagatggtc gttgagcgca agattgccgc agaagaaggt
     5161 aaaacccgtc acgactacgg ccgcgaagct ttcatcgaca aaatttggga atggaaagcg
     5221 gaatccggcg gcaccattac ccgtcagatg cgccgtctcg gcaactccgt cgactgggag
     5281 cgtgaacgct tcaccatgga cgaaggcctg tccaatgcgg tgaaagaagt tttcgttcgt
     5341 ctatataaag aagacctgat ttaccgtggc aaacgcctgg taaactggga cccgaaactg
     5401 cgcaccgcta tctctgacct ggaagtggaa aaccgcgaat cgaaaggttc gatgtggcac
     5461 atccgctatc cgctggctga cggtgcgaaa accgcagacg gtaaagatta tctggtggtc
     5521 gcgactaccc gtccggaaac cctgctgggc gatactggcg tagccgttaa cccggaagat
     5581 ccgcgttaca aagatctgat tggcaaatat gtcattctgc cgctggttaa ccgtcgtatt
     5641 ccgatcgttg gcgacgaaca cgccgacatg gaaaaaggca ccggctgcgt gaaaatcact
     5701 ccggcgcacg actttaacga ctatgaagtg ggtaaacgtc acgcgctgcc gatgatcaac
     5761 atcctgacct ttgacggcga tatccgtgaa agcgcccagg tgttcgatac caaaggtaac
     5821 gaatctgacg tttattccag cgaaatcccg gcagagttcc agaaactcga gcgttttgct
     5881 gcacgtaaag cggtcgttgc tgcggttgac gcactcggcc tgctggaaga aattaaaccg
     5941 cacgacctga ccgttcctta cggcgaccgt ggcggcgtag ttatcgaacc aatgctgacc
     6001 gaccagtggt acgtgcgtgc cgatgtactg gcgaaaccgg cggttgaagc ggttgagaac
     6061 ggcgacattc agttcgtacc gaagcagtac gaaaacatgt acttctcctg gatgcgcgat
     6121 attcaggact ggtgtatctc tcgtcagctg tggtggggtc accgtatccc ggcatggtac
     6181 gacgaagcgg gtaacgttta tgttggccgc aacgaagatg aagtgcgtaa agaaaataac
     6241 ctcggtgccg acgttgctct acgtcaggac gaagacgttc tcgacacctg gttctcttct
     6301 gcactgtgga ccttctctac ccttggctgg ccggaaaaca ccgacgccct gcgtcagttc
     6361 cacccaacca gcgtgatggt atccggcttc gacatcatct tcttctggat tgcccgcatg
     6421 atcatgatga ccatgcactt catcaaagat gaaaatggca aaccgcaggt gccgttccac
     6481 actgtttaca tgaccggtct gattcgtgac gacgaaggcc agaagatgtc caaatccaag
     6541 ggtaacgtta tcgacccgct ggatatggtt gacggtattt cgctgccaga actgctggaa
     6601 aaacgtaccg gcaatatgat gcagccgcag ctggcggaca aaatccgtaa gcgcaccgag
     6661 aaacagttcc cgaacggcat tgagccgcac ggcaccgatg ccctgcgctt caccctggcg
     6721 gcactggcgt ctaccggtcg tgacatcaac tgggatatga agcgtctgga aggctaccgt
     6781 aacttctgta acaagctgtg gaacgccagc cgctttgtgc tgatgaacac ggaaggtcag
     6841 gattgcggct tcaacggtgg tgaaatgacg ctgtcgctgg cggaccgctg gattctggca
     6901 gagttcaacc agaccatcaa agcgtaccgc gaagcgctgg acagcttccg cttcgatatc
     6961 gctgcaggca ttctgtatga gttcacctgg aaccagttct gtgactggta tctggagctg
     7021 actaagccgg taatgaacgg tggcaccgaa gccgaactgc gtggtactcg ccatacgctg
     7081 gtgaccgtgc tggaaggtct gctgcgcctc gcgcatccga tcattccgtt catcaccgaa
     7141 accatctggc agcgtgtgaa agtactttgc ggtatcactg ccgacaccat catgctgcag
     7201 ccgttcccgc agtatgatgc atctcaggtt gatgaagcgg cgctggccga caccgagtgg
     7261 ctgaaacagg cgatcgttgc ggtacgtaac atccgtgcag aaatgaatat cgcgccgggc
     7321 aaaccgctgg agctgctgct gcgtggttgc agcgcggatg cagaacgtcg cgtaaatgaa
     7381 aaccgtggct tcctgcaaac cctggcgcgt ctggaaagca tcaccgtgct gcctgccgat
     7441 gacaaaggtc cggtttccgt tacgaagatc atcgacggcg cagaactgct gatcccgatg
     7501 gctggcctca tcaacaaaga agatgagctg gcgcgtctgg cgaaagaagt ggcgaagatc
     7561 gaaggcgaaa tcagccgtat cgagaacaag ctggcgaatg aaggctttgt cgcccgcgca
     7621 ccggaagcgg tcatcgcgaa agagcgtgaa aagctggaag gctatgcaga agcgaaagcg
     7681 aagctgattg aacagcaggc tgttatcgcc gcgctgtaat caaatcacag cgatgaaaac
     7741 gaaggccgta gcatgctccg gcctttttta tctcttacag aaatggtaaa gaaggcataa
     7801 ttccccgtga aatcctggct aagaagcctt tatctggttg ttcttcttta ttgattaaag
     7861 gaaggtcatc caaatcgccc agcaaatacg tattttttgc ctgccagtca atcatccata
     7921 ttttcagcag tggataagcc agaccgcccg taatcccgga tatcaccacc aacgcacaca
     7981 tgcgataaag cataccgtgg tacgttaaag ttgagcgaaa acgaatacgc ccatcattca
     8041 gtgacaggtt gctcataaaa tgatttcgca acgacaccgt taaataactg gtgctaacag
     8101 caaccccaaa ataatagatt aactgcgcga ttatcatttt acgttgcatt tccataaatt
     8161 gctgtaaatt ctcaatatca tcatttgcat acacagaact atcatacgca tttaatattt
     8221 gatcgaagat aatataacca gcaacagcga gaaaaggtaa taaagctaaa aatgcgagaa
     8281 tggcatattt tatacaatac gtagtatcta atttcacctt gaaacgatgt ataccgaaac
     8341 tggtattgct ccagagaaaa ctcattacca ggctatataa agtaccatta aaaataccaa
     8401 tggaaacaat accaactatt gccatcagaa ccacagatat aataacacta cttgaactat
     8461 tggcatgtag catctttgtc gagataaaga aaacagctcc catcccaatg gccattaaaa
     8521 tcggcaagaa aaaggttacc caccagaacc ctttcaaaga gcaattaaaa ctaaatctta
     8581 cgccgttgag actggtcatc aaggcctgat aacgcagtcc ttttgctgcc ataaatataa
     8641 gcaaaaccaa cagtgacaaa gtcaaaacac agccaacaag cggcatatct gctgacactg
     8701 tcattaagat tgcgaaatag aaaaaaacaa aaacaagaca actaacaaaa acattcccac
     8761 cggtaattcc ataagaaaat cgttgtccgt taacttccat attagcatag agataacgct
     8821 tacatttcat taatgcccat ggcaaataga tacctagcgt tataatcgtt aacaacacat
     8881 tcaccacaca aataagaaaa tatctctcac ctgtgccatg aaaaacaaac gaatgggacg
     8941 gaacatccat ttcattaata acttgagcca taaaaattcc ctgaattaaa aaatccattg
     9001 atataattta tatatacaga cagtaaaatg ttctgccacg ttacaatact cttatcagta
     9061 ataggctggc aaaaacttta taagtcgctt gcgcacgtaa gaagagagtg gtattaaaca
     9121 aatgtataat tactttattt ttattgggtt aaactatgaa taacattgcg ccgcaatcac
     9181 ctgtaatgcg tcgcctgacg cagcaggata atcccgctat cgcccgcgtc attcgtcagg
     9241 tatccgccga atacggtctt accgctgata aaggctacac cgtcgccgat ccgaaccttg
     9301 acgagttgta tcaagtgtat agtcagcctg gccatgcata ttgggtggtt gagttcgatg
     9361 gtgaagtggt cggcggcggt gggattgcgc cattagcagg tagtgaatcg gacatttgcg
     9421 aactgcaaaa gatgtatttt cttccggcta ttcgcggtaa agggctggcg aaaaaactgg
     9481 ccttaatggc gatggagcag gcacgagaga tgggcttcaa acgctgttat ctggaaacga
     9541 ccgctttttt aaaggaagcc attgcacttt atgagcattt gggctttgag catatcgact
     9601 atgcgcttgg ctgcacgggc catgtcgatt gtgaagtgcg gatgctacgc gaactctaaa
     9661 aaaatgcccg ctagtgtgtg ctatcgggca ttttaatcaa ttaattagtg gcgaaccccg
     9721 tcatcgtctt cgtcgacaaa atcttcatcg tcgccgtctt cgccgttagg atcttcaaag
     9781 taagtgcccc aaccatcgta ctcaacgtca aatttctccg ccagcgtcat cagttgttca
     9841 acctgggcat cgatcagatc ggcattcaac gcgcactcgc tgaggatgtc gcagcaaatc
     9901 acgatatcac catcttcaac ttccagctct tctggatcgg tcacttcgta accgagttta
     9961 aacgcttcaa ctgctgcttt ttccagggtt tccagatcgt ctgcggaaag atggtgttcg
    10021 atggtgtaca gcgcgtccgg atcgctgcca tcttccagta attcttcaat aatcaaacgt
    10081 gtttcttcac gctgttcttc cagttgttcc gggtttgcca tggctcattc ctcttaatgt
    10141 cctgccgata ctcttattgt cacacaccac tgacattgcc tccacctttg tgacaaagat
    10201 ttatgcttta gacttgcaaa tgaataatca tccatataaa ttgaatttta attcattgag
    10261 gcgatagcca caggagggat ctatgtccgg gttttatcat aagcatttcc tgaaattact
    10321 cgatttcacg ccagctgaac tcaacagcct gttgcagtta gccgcgaagc tgaaagccga
    10381 taagaaaagc ggtaaagaag aagccaaact cactggtaaa aacatcgcgc tcatcttcga
    10441 aaaagactcg acccgtaccc gatgctcttt cgaagttgcc gcatatgacc agggtgctcg
    10501 cgttacttat ctcggcccaa gcggcagcca gattggtcat aaagagtcga ttaaagacac
    10561 tgcccgcgtg cttggtcgca tgtatgacgg tattcagtat cgcggctatg gtcaggagat
    10621 tgttgaaaca ctggcggaat acgctggcgt gccggtatgg aacggcctga ccaatgagtt
    10681 tcaccccacg cagctgctgg cggatctcct caccatgcag gagcatttac ctggcaaagc
    10741 gttcaacgaa atgacgctgg tctatgcagg tgacgcacgt aacaacatgg gcaattcgat
    10801 gctcgaagct gcggcgctta ccggtctgga tttgcgtctg gtcgcgccac aggcatgctg
    10861 gccggaagct gcgctggtta cggaatgccg cgctctggca cagcaaaatg gcgggaatat
    10921 tacgctaacg gaagatgtag ccaagggagt agaaggtgct gactttatct ataccgatgt
    10981 gtgggtgtcg atgggggaag caaaagagaa atgggcagaa cggattgcat tactgcgtga
    11041 ttatcaggtg aacagcaaga tgatgcagtt gaccggtaac ccggaggtca aattcctcca
    11101 ctgcctgccc gcttttcatg acgaccagac gacgcttggt aagaaaatgg cggaagagtt
    11161 tggcctacat ggcggaatgg aagtgactga tgaggtcttc gaatctgccg ccagcattgt
    11221 ttttgatcag gcggaaaacc gcatgcatac catcaaagcg gtgatggtcg cgacgctcag
    11281 taaataattg atattgctat aaagatgccg ggaaatacaa accatcccgg catcacatta
    11341 ttttatgcag tgataggttt attattccac ccaaattttt ctattgct
//
LOCUS       DAPOAV010000116        11361 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.116, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000116 DAPOAV010000000
VERSION     DAPOAV010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11361
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.116"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            321..902
                     /gene="mdaB"
                     /locus_tag="RN951_003867"
     CDS             321..902
                     /gene="mdaB"
                     /locus_tag="RN951_003867"
                     /EC_number="1.6.5.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH:quinone oxidoreductase MdaB"
                     /protein_id="HDX2528796.1"
                     /translation="MSNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRA
                     DSDYDVKAEVQNFLWADVVIWQMPGWWMGAPWTVKKYIDDVFTEGHGTLYASDGRTRK
                     DPSKKYGSGGLVQGKKYMLSLTWNAPMEAFTEKDQFFHGVGVDGVYLPFHKANQFLGM
                     EPLPTFIANDVIKMPDVPRYTEEYRKHLVEIFG"
     gene            933..1247
                     /locus_tag="RN951_003868"
     CDS             933..1247
                     /locus_tag="RN951_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDX2528797.1"
                     /translation="MLTVIAEIRTRPGQHHRQAVLDQFAKIVPTVLKEEGCHGYAPMV
                     DCAAGVSFQSMAPDSIVMIEQWESIAHLEAHLQTPHMKAYSEAVKGDVLEMNIRILQP
                     GI"
     gene            complement(1295..3187)
                     /gene="parE"
                     /locus_tag="RN951_003869"
     CDS             complement(1295..3187)
                     /gene="parE"
                     /locus_tag="RN951_003869"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HDX2528798.1"
                     /translation="MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSV
                     DEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHPEEGVPAVELILCRLHAGGKFSN
                     KNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN
                     TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDG
                     LNDYLAEAVNGLPTLPEKPFIGNFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQG
                     GTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVLSVKMQDPQFAGQTK
                     ERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQRRMRAAKKVVRKKLT
                     SGPALPGKLADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEV
                     SSDEVLATQEVHDISVAIGIDPDSDDLSQLRYGKICILADADSDGLHIATLLCALFVK
                     HFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNVQRFKGL
                     GEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGD
                     MAEIEV"
     gene            complement(3216..3797)
                     /gene="yqiA"
                     /locus_tag="RN951_003870"
     CDS             complement(3216..3797)
                     /gene="yqiA"
                     /locus_tag="RN951_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase YqiA"
                     /protein_id="HDX2528799.1"
                     /translation="MSTLLYLHGFNSSPRSAKASLLKNWLAEHHPDVEMIIPQLPPYP
                     SDAAELLESIVLEHGGDSLGIVGSSLGGYYATWLSQCFMLPAVVVNPAVRPFELLTDY
                     LGQNENPYTGQQYVLESRHIYDLKVMQIDPLEAPDLIWLLQQTGDEVLDYRQAVAYYA
                     SCRQTVIEGGNHAFTGFEDYFNPIVDFLGLHHL"
     gene            complement(3797..4624)
                     /gene="cpdA"
                     /locus_tag="RN951_003871"
     CDS             complement(3797..4624)
                     /gene="cpdA"
                     /locus_tag="RN951_003871"
                     /EC_number="3.1.4.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3',5'-cyclic-AMP phosphodiesterase"
                     /protein_id="HDX2528800.1"
                     /translation="MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQA
                     VLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMY
                     SALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL
                     LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLL
                     ATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY"
     gene            complement(4649..5071)
                     /locus_tag="RN951_003872"
     CDS             complement(4649..5071)
                     /locus_tag="RN951_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1249 family protein"
                     /protein_id="HDX2528801.1"
                     /translation="MKRYTPDFPEMMRLCEMNFSQLRRLLPRNDAPGETVSYQVANAQ
                     YRLTIVESTRYTTLVTIEQTAPAISYWSLPSMTVRLYHDAMVAEVCSSQQIFRFKARY
                     DYPNKKLHQRDEKHQINQFLADWLRYCLAHGAMAIPVY"
     gene            complement(5072..5701)
                     /gene="nudF"
                     /locus_tag="RN951_003873"
     CDS             complement(5072..5701)
                     /gene="nudF"
                     /locus_tag="RN951_003873"
                     /EC_number="3.6.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribose diphosphatase"
                     /protein_id="HDX2528802.1"
                     /translation="MLKPDNLPVTFGKNDVEIIARETLYRGFFSLDLYRFRHRLFNGQ
                     MSHEVRREIFERGHAAVLLPFDPVRDEVVLIEQIRIAAYDTSETPWLLEMVAGMIEEG
                     ESVEDVARREAIEEAGLIVKRTKPVLSFLASPGGTSERSSIMVGEVDATTASGIHGLA
                     DENEDIRVHVVSREQAYQWVEEGKIDNAASVIALQWLQLHHQALKNEWA"
     gene            5906..7387
                     /gene="tolC"
                     /locus_tag="RN951_003874"
     CDS             5906..7387
                     /gene="tolC"
                     /locus_tag="RN951_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane channel protein TolC"
                     /protein_id="HDX2528803.1"
                     /translation="MKKLLPILIGLSLSGFSSLSQAENLMQVYQQARLSNPELRKSAA
                     DRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDANGINSNATSASLQLTQSIFDMSK
                     WRALTLQEKAAGIQDVTYQTDQQTLILNTATAYFNVLNAIDVLSYTQAQKEAIYRQLD
                     QTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEQLRQITGNYYPELAAL
                     NVENFKTDKPQPVNALLKEAEKRNLSLLQARLSQDLAREQIRQAQDGHLPTLDLTAST
                     GISDTSYSGSKTRGAAGTQYDDSNMGQNKVGLSFSLPIYQGGMVNSQVKQAQYNFVGA
                     SEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIV
                     DVLDATTTLYNAKQELANARYNYLINQLNIKSALGTLNEQDLLALNNALSKPVSTNPE
                     NVAPQTPEQNAIADGYAPDSPAPVVQQTSARTTTSNGHNPFRN"
     gene            7535..8206
                     /locus_tag="RN951_003875"
     CDS             7535..8206
                     /locus_tag="RN951_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417509.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 family protein"
                     /protein_id="HDX2528804.1"
                     /translation="MKRTKSIRHASFRKNWSARHLTPVALAVATVFMLAGCEKSDETV
                     SLYQNADDCSAANPGKSAECTTAYNNALKEAERTAPKYATREDCVAEFGEGQCQQAPA
                     QAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKY
                     TDATGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSATGTSS
                     RSMGG"
     gene            8212..9372
                     /locus_tag="RN951_003876"
     CDS             8212..9372
                     /locus_tag="RN951_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HDX2528805.1"
                     /translation="MERVSITERPDWREKAHEYGFNFHTMYGEPYWCEDAYYKLTLAQ
                     VEKLEEVTAELHQMCLKVVEKVIASDELMTKFRIPKHTWSFVRQSWLTHQPSLYSRLD
                     LAWDGTGEPKLLENNADTPTSLYEAAFFQWIWLEDQLNAGNLPEGSDQFNSLQEKLID
                     RFVELREQYGFQLLHLTCCRDTVEDRGTIQYLQDCATEAEIATEFLYIDDIGLGEKGQ
                     FTDLQDQVISNLFKLYPWEFMLREMFSTKLEDAGVRWLEPAWKSIISNKALLPLLWEM
                     FPNHPNLLPAYFAEDDHPQMEKYVVKPIFSREGANVSIIENGKTIEAAEGPYGEEGMI
                     VQQFHPLPKFGDSYMLIGSWLVNDQPAGIGIREDRALITQDMSRFYPHIFVE"
     gene            complement(9410..10198)
                     /gene="ygiD"
                     /locus_tag="RN951_003877"
     CDS             complement(9410..10198)
                     /gene="ygiD"
                     /locus_tag="RN951_003877"
                     /EC_number="1.13.11.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001356237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4,5-DOPA dioxygenase extradiol"
                     /protein_id="HDX2528806.1"
                     /translation="MSSTRMPALFLGHGSPMNVLEDNLYTRSWQKLGMTLPRPQAIVV
                     VSAHWFTRGTGVTAMETPPTIHDFGGFPQALYDTHYPAPGSPVLAQHLVELLAPVPVT
                     LDKEAWGFDHGSWGVLIKMYPDADIPMVQLSIDSSKPAAWHFEMGRKLAALRDEGIML
                     VASGNVVHNLRTVKWHGDSSPYPWAMSFNEYVKANLTWQGAVEQHPLVNYLDHEGGAL
                     SNPTPEHYLPLLYVLGAWDGQEPITIPVDGIEMGSLSMLSVQIG"
     gene            10341..11114
                     /gene="zupT"
                     /locus_tag="RN951_003878"
     CDS             10341..11114
                     /gene="zupT"
                     /locus_tag="RN951_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HDX2528807.1"
                     /translation="MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIM
                     LLISLMEMLPAALAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLP
                     KSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPV
                     YAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAAVAGIMVALSVD
                     ELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG"
     gene            complement(11172..11342)
                     /locus_tag="RN951_003879"
     CDS             complement(11172..11342)
                     /locus_tag="RN951_003879"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528808.1"
                     /translation="MFIAWYWIVLIALVVVGYFLHLKRYCRAFRQDRDALLEARNKYL
                     NSTREETAEKVE"
BASE COUNT         2823 a         3059 c         2805 g         2674 t
ORIGIN      
        1 atatatcagt acgctcataa aaatccattt ataattatca acatgacacg ttgatatttt
       61 catcttttac ttattcaaag ccatattttc aatcccaaaa aaaaccgaac caaacgtgta
      121 aattattccg gtgcgagtaa gaattatgag gaatggctat cagtattgtc attttcagaa
      181 aatatttatc ctgcatcggt gagtcagagc aagatcagac ttttgctaaa ttcgcaaaag
      241 actttgcaca ttttgctaat ttcaccgtac cgctctgtga cgtactatag tcggcaaacg
      301 tctcaccttg aggttaaaaa atgagcaaca tcctgattat caacggcgcg aaaaaattcg
      361 cccactccaa tggtcaactg aacgacaccc tgaccgaagt cgcggatggc acactgcgcg
      421 acctcgggca tgatgtccgc atcgttcgcg ccgacagcga ctacgatgtc aaagcggaag
      481 tacaaaactt tctctgggct gatgtggtga tctggcagat gccaggctgg tggatgggcg
      541 cgccgtggac agtgaaaaaa tatattgatg atgtattcac cgaaggtcat ggaacgctgt
      601 atgccagcga tggccgtacc cgcaaagatc cgtcaaaaaa atacggttcc ggcggcctgg
      661 tacagggcaa aaaatatatg ctttctctga cctggaacgc accaatggaa gccttcaccg
      721 aaaaagatca attcttccac ggcgttggcg tcgacggtgt gtatctgccg ttccataaag
      781 caaaccaatt ccttggcatg gaaccgctgc cgacatttat cgctaatgac gtgataaaaa
      841 tgcctgatgt tccccgctat actgaagaat atcgcaagca tcttgtggaa atttttggtt
      901 aactagagct caggctttag aaggagttaa ccatgcttac cgtaatcgca gaaatccgta
      961 ctcgtcctgg tcaacatcac cgtcaggcgg tattggatca gtttgctaaa atcgttccaa
     1021 ccgtactgaa agaagaaggt tgccacggct atgcgccaat ggtggattgc gctgctggcg
     1081 tgagtttcca gtctatggca ccggattcta tcgtgatgat tgagcagtgg gaaagcatcg
     1141 cgcatcttga agcgcatctg caaaccccgc acatgaaggc gtacagcgaa gccgtaaaag
     1201 gcgacgtgct ggagatgaat atccgcatcc tgcaacctgg gatttaaacc tgccttgttt
     1261 gcccggccat cctgaccggg caatgttctt tcctttaaac ctcaatctcc gccatgtcgc
     1321 ctttctcttg caaccagttg cggcgatctt ccgagcgttt cttcgccagc agcatatcca
     1381 tcatcgcgtc agtacgctga tcgtcttcat catcgatagt caactgcacc agacggcgag
     1441 tgttcggatc aagcgtggtt tcacgcaatt gcatcgggtt catttccccc agacctttaa
     1501 aacgctggac gttcggcttg cctttcttgc gttttaattg ctcaagtacg ccctctttct
     1561 cttcttccgt cagcgcgtaa taaacctctt tcccgagatc aatacggtag agcggtggca
     1621 gtgcgacgta aacgtgaccg tgtttcacca acgcgcggaa gtgttttacg aacaaagcgc
     1681 agagcagcgt ggcaatgtgc agaccatcag agtccgcatc cgcgaggata cagattttgc
     1741 cataacgaag ctggctcaga tcgtcgctgt caggatcgat accgatcgct accgaaatat
     1801 catgcacttc ctgcgtggcc agcacttcgt cggaagagac ttcccaggtg ttaaggatct
     1861 tacctttcag tggcatgatc gcctgatatt cgcgatcgcg cgcctgcttg gcagatccgc
     1921 ctgcggagtc accttccacg aggaacagtt cggtacggtt aaggtcctgc gcggtacagt
     1981 cagccagttt gccaggcagc gccgggccgc tggtcagctt tttacgcacc acttttttag
     2041 ccgcacgcat acgacgctgg gcgctggaaa tcgccatctc tgccagcaac tccgccgcct
     2101 gaacgttctg gttcagccac aggataaagg catctttcac cacgcctgaa acgaatgccg
     2161 cgcattgacg cgaagagaga cgctctttgg tctgcccggc aaactgcgga tcctgcattt
     2221 tcaccgacag aacataggcg cagcgatccc agatatcttc cgccgacagc ttcacgccgc
     2281 gcggcagaat gttgcggtat tcacagaact cacgcatcgc gtccaacagg ccctgacgca
     2341 gaccattaac atgggtaccg ccctgcatcg ttgggataag gttgacgtag ctttcggtca
     2401 gcagttcacc gccttccggc agccacagta gcgcccagtc cacagcttca gtatcaccag
     2461 cgaaattacc gataaacggt ttttccggca gcgtcggcag accatttacc gcttccgcca
     2521 ggtaatcatt cagaccgtcc tgatagcacc agcgttgttc ggtattgttg atctcatctt
     2581 taaaagtgat ctcaacgcca gggcacaata ccgctttggc tttcagcaca tgtgtcaggc
     2641 gtgaaacaga aaaacgcggg ctgtcaaaga aggtttcatc cggccagaag tgcacgctgg
     2701 taccagtatt gcgtttaccg caagtgccga caacctgtaa atcctgcacc ttttcgccat
     2761 tttcaaaggc gatgttataa acctgaccat cgcggcgcac gttaacttct acgcgcttcg
     2821 acagggcgtt aaccaccgaa atccccacgc catgcaggcc gccagagaac tggtaatttt
     2881 tgttagagaa tttaccgcct gcatgcagac ggcaaagaat cagttcaacc gccggtacac
     2941 cctcttccgg gtgaatatcc accggcatcc cgcgcccatc gtcaataact tctaacgact
     3001 ggtcagcatg taagattaca tccacgcgtt ttgcgtgacc cgccagtgct tcatcgacac
     3061 tgttatcaat aacttcttgc cccaaatggt tagggcgagt ggtatcggta tacatccccg
     3121 gacggcggcg aaccggctca agcccggtga gtacctcaat ggcatcagcg ttataagttt
     3181 gcgtcatggt ttaagttagt aattcgagtt gatcgtcaga gatggtgcag accaagaaaa
     3241 tcgacgatcg ggttgaaata atcttcgaag cccgtgaatg cgtggttgcc gccttctatg
     3301 acagtctggc ggcaggaagc gtagtacgcc accgcctggc ggtaatccag cacttcatct
     3361 cccgtctgtt gcagcagcca gatcaaatcc ggcgcttcca gcgggtcaat ctgcatgact
     3421 ttgagatcgt aaatatggcg tgactctagc acatattgct gcccggtgta ggggttctcg
     3481 ttctgaccga gatagtccgt cagcagttca aacgggcgta ccgccgggtt taccaccact
     3541 gcgggcagca taaaacattg cgacaaccag gtggcgtaat atccccccag tgacgaaccg
     3601 acaataccca gcgaatcgcc gccatgttcc aggacaatgg attccaacag ctctgccgcg
     3661 tcggaaggat acggcggcaa ctgcggaatg atcatctcaa cgtcagggtg atgttccgcc
     3721 agccagtttt ttaacaagct cgcttttgca gagcgcggcg agctgttgaa accgtgtaaa
     3781 taaagaagcg tagacatcag tagccttctg aagcggtatc aggttggaaa cgtgtgtccg
     3841 ccaggcgatg cacctcggtg gtcagcgtgc catcagcatg taactcgaga gtacgccagc
     3901 cgggcgcgat ggtgtccagc gtaaagttgg aacagtgcgg cttaaactgc acacaggtcg
     3961 acggcgttgc cagcaggcgg cgaccgttcc agtcgagatc cagctcctga tgaatatgac
     4021 cgcacagcaa gtatttgacg tgcggaaact tcgccagcac ggtatccagt tcgcccgcgt
     4081 tacgcagact gtgttgatcg agccaactac aacccgcagg tagcggatga tgatgcagca
     4141 gcagcaacgt atggcgttct ggcgcatcgg ccagtttacg ttccagccac tcaagctgaa
     4201 actcgctcag ctcaccgtgc ggcacgccaa acacctggct atccagcaac aggatttgcc
     4261 attgctcacc aataaacacg cgcttcgccg gggagatacc cgcatcctgt aacgcgctgt
     4321 acatcgcggg ctggaaatcg tggttgcccg gcagccagac gcagggcgca cgaaaacttg
     4381 cgatgccttc agcgaaatgc tgataggccg cagaggattg atcctgcgct aaatcacctg
     4441 tcgcgacaat caggtcgaat tcgtgctgat gtggacgaat cgcctccagc accgcctggt
     4501 agctttccca ggtgtttacc cctaacaggg cttcgtgctt ttgtgcaaac aggtgagtat
     4561 cggtaatttg taaaatcctg actctggcct caccagccag aggaagggtt aacaggcttt
     4621 ccaaatggtg tccttaggtt tcacgacgct agtaaaccgg aatcgccatc gctccatgtg
     4681 ctaaacagta tcgcaaccag tccgctaaaa actggttaat ttgatgcttt tcgtcgcgtt
     4741 gatgcaactt tttattagga taatcatacc gcgctttgaa gcgaaaaatc tgctggcttg
     4801 aacacacttc agccaccatc gcgtcatgat acagacgcac cgtcattgac ggaaggctcc
     4861 agtaactgat cgcgggcgca gtctgttcta ttgtcaccag ggtagtgtat cgggtcgatt
     4921 ccacaatcgt cagccgatat tgtgcgtttg ccacctgata gcttacagtt tcgccgggtg
     4981 cgtcattgcg cggtaacaaa cggcgcaatt gtgaaaagtt catctcgcac aggcgcatca
     5041 tttcaggaaa gtcaggtgtg taacgcttca tttatgccca ctcatttttt aacgcttgat
     5101 gatgcagctg cagccattgc aaagcgatga ccgacgctgc gttgtcgatt ttcccctctt
     5161 ctacccactg gtatgcctgt tcccggctta ccacatgaac gcgaatatct tcgttttcat
     5221 cagccagacc atgaataccg cttgcggtcg tggcgtccac ttcgcccacc ataattgacg
     5281 aacgctcact ggtgcccccc gggcttgcca ggaaacttaa caccggtttg gtccgtttga
     5341 ctatcagtcc cgcctcttca atcgcttcgc gacgggcaac atcttccaca ctttcaccct
     5401 cttctatcat cccggcaacc atctccagta gccagggggt ttcactggtg tcgtatgcgg
     5461 caatccgaat ctgctcaatc agcacaactt catcacgcac tgggtcaaag ggtagcaaga
     5521 ctgcggcgtg accgcgctca aaaatttccc tccgtacctc atgactcatt tgcccgttga
     5581 ataaacgatg acgaaatcta taaagatcta atgaaaaaaa gccgcgataa agtgtttctc
     5641 gtgcaataat ttctacatcg tttttgccaa atgtaacggg caggttgtct ggcttaagca
     5701 ttgttaatgt cctggcacta atagtgaatt aaatgtgaat ttcagcgacg tttgactgcc
     5761 gtttgagcag tcatgtgtta aattgaggca cattaacgcc ctatggcacg taacgccaac
     5821 cttttgcggt agcggcttct gctagaatcc gcaataattt tacagtttga tcgcgctaaa
     5881 tactgcttca ccacaaggaa tgcaaatgaa gaaattgctc cccattctta tcggcctgag
     5941 cctttctggg ttcagttcgt tgagccaggc cgagaacctg atgcaagttt atcagcaagc
     6001 acgccttagt aacccggaat tgcgtaagtc tgccgccgat cgtgatgctg cctttgaaaa
     6061 aattaatgaa gcgcgcagtc cattactgcc acagctaggt ttaggtgcag attacaccta
     6121 tagcaacggc taccgcgacg cgaacggcat caactctaac gcgaccagtg cgtccctgca
     6181 gttaactcaa tccatttttg atatgtcgaa atggcgtgcg ttaacgctgc aggaaaaagc
     6241 agcagggatt caggacgtca catatcagac cgatcagcaa accttgatcc tcaacaccgc
     6301 gaccgcttat tttaacgtgt tgaatgctat tgacgttctt tcctatacac aggcacaaaa
     6361 agaagcgatc taccgtcaat tagatcaaac cacccaacgt tttaacgtgg gcctggtagc
     6421 gataaccgac gtgcagaacg cccgcgcgca gtacgatacc gtgctggcga acgaagtgac
     6481 cgcacgtaat aaccttgata acgcggtaga gcagctgcgc cagatcaccg gtaactacta
     6541 tccagaactg gcagcgctga atgtcgaaaa ctttaaaacc gacaaaccac agccggttaa
     6601 cgcgctgctg aaagaagccg aaaaacgcaa cctgtcgctg ttacaggcac gcttgagcca
     6661 ggacctggcg cgcgagcaaa ttcgccaggc gcaggatggt cacttaccga cgctggattt
     6721 aacggcttct accgggattt ctgacacctc ttatagcggt tcgaaaactc gtggtgccgc
     6781 tggtacccag tatgacgaca gcaatatggg ccagaacaaa gtgggcctga gcttctcgct
     6841 gccgatttat cagggcggaa tggttaactc gcaggtgaaa caggcccagt acaactttgt
     6901 tggtgccagc gagcaactgg aaagcgcgca tcgtagcgtc gtgcaaaccg tacgttcctc
     6961 cttcaacaac attaatgcat ctatcagtag cattaacgcc tacaaacaag ccgtagtttc
     7021 cgctcaaagc tcattagacg cgatggaagc gggctactcg gtcggtacgc gtaccattgt
     7081 tgatgtgttg gatgcaacca ccacgctgta caacgctaag caagagctgg caaatgcgcg
     7141 ttataactac ctgattaatc agctgaatat taagtcagcc ctgggtacgt tgaacgagca
     7201 ggatctgctg gcactgaaca atgcgctgag caaaccggtt tccactaatc cggaaaacgt
     7261 tgccccgcaa acgccggaac agaatgctat tgctgatggt tatgcgcctg atagcccggc
     7321 acccgtcgtt cagcaaacat ccgcacgcac taccaccagt aacggtcata accctttccg
     7381 taactgatga cgacgacggg gcttcggccc cgtctgaacg taaggcaacg taaagatacg
     7441 ggttatctgc cgcattcttc ccccttctcg cttcaatttc gaccagccat cctctattct
     7501 gatgggtatt taccactggt cccggaagac aaaaatgaaa cggacaaaat ccatacgcca
     7561 cgcatcgttc cgcaaaaact ggagcgcgcg ccatctgaca ccagtcgctc tcgcggttgc
     7621 cactgttttt atgctggctg gctgtgaaaa gagtgatgaa acagtgtctc tctatcaaaa
     7681 tgctgacgac tgttcagctg caaacccagg caaaagcgcc gaatgtacca ccgcgtacaa
     7741 caatgcgctg aaagaagccg aacgtactgc gccgaaatac gccacccgtg aagactgtgt
     7801 tgctgaattt ggtgaaggtc agtgccagca ggcaccagcc caggctggca tggcaccaga
     7861 aaaccaggcg caggcccagc aatccagcgg gagtttctgg atgccgctga tggccggtta
     7921 catgatgggg cgtctgatgg gcggcggcgc gggatttgca cagcagccgc tgttctcctc
     7981 gaaaaaccca gccagcccgg cttacggtaa atataccgac gcgacgggta aaaactatgg
     8041 cgcagcccag ccaggccgca ccatgaccgt accgaagaca gccatggcac caaaaccggc
     8101 gaccaccact accgttaccc gtggcggttt tggtgaatct gttgccaaac aaagcactat
     8161 gcagcgtagc gcaactggca cctcttctcg ttcaatgggt ggctgatacc gatggaaaga
     8221 gtcagtatta ccgagcgccc ggactggcgt gagaaagccc acgaatacgg tttcaatttt
     8281 cacaccatgt acggcgagcc gtactggtgt gaagatgctt actacaagtt gaccctcgcc
     8341 caggttgaaa agctggaaga agtcaccgcc gaactgcacc agatgtgcct gaaagtggtg
     8401 gaaaaagtga tcgccagcga tgagctgatg accaaattcc gcattccaaa acacacctgg
     8461 agttttgtgc gccagtcatg gctgacgcac cagccatcgc tttattcgcg tcttgatctg
     8521 gcgtgggatg gcactggcga acctaaactt ctggaaaata acgccgatac gccaacgtca
     8581 ctatacgagg cggcgttctt tcagtggatc tggctggaag atcagcttaa cgccggtaac
     8641 ttgccggagg gcagcgacca gtttaacagt ctgcaagaaa aactgatcga tcgcttcgtt
     8701 gagctgcgtg aacagtatgg cttccagttg ctgcatctca cctgctgtcg cgacacggtg
     8761 gaagatcgcg gaaccattca gtatttgcag gactgcgcaa cggaagctga aattgctact
     8821 gagttcctct acatcgatga tatcgggtta ggtgaaaaag gtcagttcac ggatttacag
     8881 gatcaggtaa tttccaacct gttcaagctg tatccgtggg aatttatgtt gcgtgagatg
     8941 ttttccacca agctggagga tgcaggcgta cgctggctgg aaccggcgtg gaagagcatt
     9001 atctccaaca aggcacttct accgctactg tgggagatgt tcccgaatca cccgaacctg
     9061 ctgcccgctt attttgcgga agatgatcat ccgcaaatgg aaaaatatgt ggttaaaccg
     9121 atcttctccc gtgaaggcgc aaacgtgtcg atcattgaaa acggcaaaac cattgaagca
     9181 gcggaaggtc cgtatggcga agaagggatg attgttcagc aattccaccc gttaccgaaa
     9241 ttcggcgaca gctatatgct gattggtagc tggctggtga acgatcaacc cgccggaatt
     9301 ggcattcgtg aagaccgtgc attgatcacc caggatatgt ctcggtttta tccacatatt
     9361 tttgttgagt aatcaatgat gccggatggc attcgccatc cggtaattgt taacctatct
     9421 gcaccgacag catactcagg ctgcccattt ctataccatc gaccggaatg gtaattggct
     9481 cctgcccatc ccacgcacct aagacataca acaacggcag atagtgctcc ggcgttgggt
     9541 tcgataacgc gccaccttca tggtcgaggt aattcaccag aggatgctgc tctaccgccc
     9601 cttgccacgt cagattcgct ttcacatact cattaaacga catcgcccaa ggatatggtg
     9661 aactatcacc gtgccacttc actgtacgca ggttatgcac cacgttgcca ctggcgacca
     9721 acattattcc ttcatctcgc agcgctgcca gtttgcgccc catttcgaaa tgccaggcgg
     9781 caggtttgct actgtcgata ctcaactgca ccatcgggat atcggcgtca ggatacatct
     9841 taatcagcac gccccaggaa ccgtggtcaa agccccaggc ttctttatcc agcgtcaccg
     9901 ggaccggcgc taacagctca accagatgct gtgccagcac aggcgaaccc ggagcaggat
     9961 aatgcgtatc gtacagcgcc tgcgggaagc caccaaagtc atgaatcgtg ggcggcgtct
    10021 ccatcgcggt cactcctgtt ccacgggtaa accagtgagc cgaaaccacc acaatcgctt
    10081 gcgggcgtgg caatgtcatc cccaacttct gccagctgcg ggtatacaaa ttatcttcca
    10141 gcacgttcat cggactaccg tgacctaaaa acaatgctgg catacgtgtt gaagacatga
    10201 tgatatcctt aactaaaggt gtcattttga tatcctcaca atacgcttgt tcggcggagt
    10261 aagaacccgg ataacaatga tgatgatcat cagttatttt gacgatctgc ctgaaggtga
    10321 agatttataa ggagttgtcg atgtcagtac ctctcattct gaccatactg gcgggggcag
    10381 ccacgtttat tggcgcgttt ctcggcgttc tcgggcaaaa accctcgaac cgcttactgg
    10441 cgttttcgct aggatttgcg gcggggatca tgttgctcat ctcattaatg gaaatgcttc
    10501 ctgccgcact agcagctgaa ggaatgtcgc ctgtgttggg ttatggaatg tttatcttcg
    10561 gtctgcttgg ctattttggc ctggaccgca tgttgccaca tgcgcatccg caggatttaa
    10621 tgcaaaaatc ggtgcagccg ttgccaaaat cgatcaagcg cacagccatt ctgctcactc
    10681 tcggcatcag tctgcataac ttcccggaag ggattgccac ctttgtcacg gcgagcagca
    10741 acctggagct gggatttggc atcgcactgg ccgtcgcttt gcacaatatc cctgaaggtc
    10801 tggcagtggc aggcccggtt tatgcggcaa cggggtctaa acgcaccgcg attctgtggg
    10861 cggggatttc tggactagca gaaattcttg gtggtgtgct ggcgtggtta atcctcggta
    10921 gcatgatttc cccggtggtc atggcggcaa tcatggcggc ggttgcagga attatggtgg
    10981 cgctctcggt tgatgaatta atgccgctcg ccaaagagat tgaccctaat aataacccca
    11041 gctatggcgt actatgtgga atgtcagtga tgggattcag tttagtgctg ctacaaacgg
    11101 cgggaattgg ttaaaaacaa catcagaagt tgtccagcac atggacaact tctgccagct
    11161 tcacgaaagc cttattctac cttttcggct gtctcttctc tcgtactgtt taagtatttg
    11221 ttccgcgctt caagcagtgc gtctctgtcc tggcgaaacg cccgacaata acgtttcaaa
    11281 tgcaggaaat aacccaccac aaccagagca atcaatacaa tccagtacca ggcgataaac
    11341 atccttttac ccttaatatt t
//
LOCUS       DAPOAV010000117        11305 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.117, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000117 DAPOAV010000000
VERSION     DAPOAV010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11305
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.117"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            220..1146
                     /locus_tag="RN951_003880"
     CDS             220..1146
                     /locus_tag="RN951_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528809.1"
                     /translation="MSKKYQPLLITHYMSTWVTITEAVEITTKTIKQKITPSDIYRHA
                     LSGNILLSVYFQSPVILKKIQTFNGKIKFRQFEGDLLDKLCMLDRDGFIYGQNLRLCT
                     EARYVCPVQQIIDTPLIGYEYVLIQRILARELKFPSPIVGARKTNHGIIVRFSEELFQ
                     IFETMSWKERVEKQISRLPKNTALDVIKKLTEVTTIKYNHNGCFPLYTLPPDACFVIR
                     HTEVERLINLYKKRESHPISPSRMTTPLSRLFWLACKHNDTISPLLNHPYKLLSIFEQ
                     WASDDGIGEKLDAETLKNALKRGSPSSTSLSG"
     gene            1286..1471
                     /locus_tag="RN951_003881"
     CDS             1286..1471
                     /locus_tag="RN951_003881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HDX2528810.1"
                     /translation="MTSYQLLRLRQVEQKTGLKRSQIYLYMKEGAFPRSIKIGPASVA
                     WLESEIDEWINKKLSDR"
     gene            1493..1675
                     /locus_tag="RN951_003882"
     CDS             1493..1675
                     /locus_tag="RN951_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001309570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528811.1"
                     /translation="MNINIPALINFDPAGIKKSTCMYISDLPGIVLYETIPFTEYSAE
                     LLSTYSVKESISCFHP"
     gene            1660..2241
                     /locus_tag="RN951_003883"
     CDS             1660..2241
                     /locus_tag="RN951_003883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2857 domain-containing protein"
                     /protein_id="HDX2528812.1"
                     /translation="MLPSLNHIILTVALQALREGNIHHCETMGFTYDEMNLLGCLSIN
                     DLITLSQAPLPLVDITIRHDVLQKLLASSHEENRRQEQLNRAVRLGGSIALMNRYFGV
                     GSRETCARRRLLGVSVPNGRTPIPDEETDAAIWHQWQKYRVENIDSPEALDAMMQVTE
                     NLSSCTAPSLTVVWNCITHCERKNTVRRIQRAR"
     gene            2231..2440
                     /locus_tag="RN951_003884"
     CDS             2231..2440
                     /locus_tag="RN951_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="HDX2528813.1"
                     /translation="MPDEIDRDQAFNERCLEALIEQSRLRPTPTPSLQHCRFCGKAIP
                     EKRRQTLPGVTTCTDCQSILEKRRR"
     gene            2644..2811
                     /locus_tag="RN951_003885"
     CDS             2644..2811
                     /locus_tag="RN951_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528814.1"
                     /translation="MNDGSLLEKVVGHMEEKLTGNELEMLYAAADYRRAEIVINQYFD
                     KVPGNVWKYVR"
     gene            3380..3613
                     /locus_tag="RN951_003886"
     CDS             3380..3613
                     /locus_tag="RN951_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528815.1"
                     /translation="MRKPVYYAYVAQESHPDSQGEKNTWWTKVGVAFPHHGKSGLNIV
                     LTPGIAVSGKLVLLEPREENNPPQNTGPIETVS"
     gene            3686..4396
                     /locus_tag="RN951_003887"
     CDS             3686..4396
                     /locus_tag="RN951_003887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDX2528816.1"
                     /translation="MLSTTAFLAIAMQCAASIHPSTAFDVARVESGFNPYAIAEIVPK
                     AGPSFGDQHIISHLPASRGDAEHILRRLTAQDRRYSVGLMQITSTNFRHYGVSATELL
                     DPCTNLSVFEHILRDCYRRGGTLKRALSCYYSGNFSTGQQPETAFSGTSYIQRIGYPP
                     GSSRYAVPGTREDKSSVAVPLKTAPASDSSRHHEIWPGVVVRGVPAKLRQEKIFIAPF
                     SAPSVRRSFSLSPREEEE"
     gene            4396..4689
                     /locus_tag="RN951_003888"
     CDS             4396..4689
                     /locus_tag="RN951_003888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012885319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="HDX2528817.1"
                     /translation="MILFRKLKAVVPPVSACTLTTFSATPALADGFQRANTVMQKVST
                     GLHGLAAITITVAVIWIGYKTLWKGESLSQCGYIIIGGILIGGGSEIGALLMS"
     gene            4702..7440
                     /locus_tag="RN951_003889"
     CDS             4702..7440
                     /locus_tag="RN951_003889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="HDX2528818.1"
                     /translation="MAKLLKAMKRPAALWGVPMVPLLAVTGVTIIVAVWTSVALLFLL
                     PVEFLVMKSLTRNEPMRFNLIAVWLRVKGKPVANRLFGATTLMPVEHEAVDIKEFLDA
                     MKLNQCATIKKYIPYSSHIHQHVVRSPKSDLYCTWELMGTPFDCESDESLQFGTNQLH
                     GLIHSFEGMPVTFYIHNDRNTFTDNLHKDSGNPYADEVSRLYYASVGVFRRNRLFLTV
                     CYRPFVSLEKAERKRMKDSQKLKELDGALLEMLEIKSTLDTALSRYGARPLGTFTEGS
                     AVFSSQLAFYEYLLTHQWRKVRVTRTPAYDVMGAAALFFSAESGQINHANGTQYFRGL
                     EVKEFSEETATGMMDSLLYAPCDYVITQSYTCMSREEAKKAIKRTRRLLMSADDDAVS
                     QRLDLDVALDLLTSGKIAYGKHHFSIMVYSPSLENLVADTNEISNALNNIGITPVPAE
                     ISLSAAYMAQLPGNYNLRPRKGELSSQNFVELAALHNFYPGKRDKAPWGDAMALLRTP
                     SGDGYYINLHNTLADKDEFNEKNPASTCILGTNGSGKTMLMTFFEIMQQKYGREDSFS
                     PDAKTKRLTTVYLDKDRGAEMNIRALGGRYYRVISGESTGWNPFSLPATKRNINFIKQ
                     LMKILCTRNGSTIFPRDERRLSDAVNAVMNDEPQYRVYGITRMLENLPEPATKEAQEN
                     GLSIRLSQWAQGGEFGWVFDNESDTFDISNCDNFGIDGTEFLDDASVCAPISFYLLYR
                     ITSLLDGRRLVIFMDEFWKWLRDPVFKDFAYNKLKTIRKLNGMLVVGTQSPAEIIKDD
                     IAPAVIEQCGTQILAANPNADRAHYVDDMKFEPEVFDVVKGLDPQARQYVVVKNQFKR
                     GDTKRFAARVTLDLSGIGRYTKVMSGDAPNLEIFESIYREGMQPHEWLDTYLAKAL"
     gene            7459..8172
                     /locus_tag="RN951_003890"
     CDS             7459..8172
                     /locus_tag="RN951_003890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HDX2528819.1"
                     /translation="MKTHFYALIFACSLASPLAQAGGILVFDATAKLENVRQWQKEAK
                     QWMETAQHYKDQIRAYKDQLATATGVRDIASFVDQAKSLKADLEKLRKPGQALNDLLL
                     SGGSSGQFDALYEKYKIFDTCKAERSESYANVCKQQVINKAIQLEQTDEIQNQVSQAL
                     GEINSLSNRVALAKDSKESQDLANSIQLKSVMLNTLTTQWEMSVKAADKREKVLEAER
                     VKQWNQQQLNAPTADLNNL"
     gene            8180..8422
                     /locus_tag="RN951_003891"
     CDS             8180..8422
                     /locus_tag="RN951_003891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="HDX2528820.1"
                     /translation="MLSKKIILISTLTLCFSVIGCKEEAKTTKWYKEHPDELKLVYEK
                     CQKSGDATENCKNANEAHYQIKQLNAPTPDLNNLEE"
     gene            8426..9499
                     /locus_tag="RN951_003892"
     CDS             8426..9499
                     /locus_tag="RN951_003892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HDX2528821.1"
                     /translation="MSGGLFVGVEKYLIGGITDATKGLMMSYSSMMMGLAAASATIYI
                     MWRGYQTLAGKLSTPMEDTMWDIMRMAIILSFVANLGGYLDGVIDAINGIKEGFSGSD
                     NIWQLLDTLWNKAKVLGKTLHDMDDSTYIKDEGMTAQFYVWLGIFVLMIITAFVSMIA
                     EVMILLLSITAPIFIFCLMYGFLRTMFNNWLQNIFAAILTIMLSALSLRIVVNYLNLV
                     LTKATKVADSSTIVELGAQVCLAGICAAILVYLSAKLAAALAGASATVSMQGLAAVGI
                     GAAAFGAGKLAGGAIKETKRSTQDNIQGWKDANAGKPGKPGGELGYNASKARKYAIEQ
                     MIARNEARRLAQSRESAVKKFNS"
     gene            9587..9724
                     /locus_tag="RN951_003893"
     CDS             9587..9724
                     /locus_tag="RN951_003893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016157224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528822.1"
                     /translation="MKRLIALALLCALSGCAQNTLPSAFSGKGEPVNTSQIMAELNSH
                     E"
     gene            9717..10400
                     /locus_tag="RN951_003894"
     CDS             9717..10400
                     /locus_tag="RN951_003894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HDX2528823.1"
                     /translation="MNEQKLIAESRTFEQQMIDRDKRATKAGFVVGGVGLLIAVLALV
                     AVVVMLPLKQTDVDLYTVDNHTGRVEHVTRTSKTSLTATEAYQKAMAANYVKVRERYV
                     YPSLQDDYETVQVYNAPQVNDDYLALYAGKNAPDKVYKNGAHTVKVEILSNQITDGTA
                     PDKVATVRYKKIIRRLADNSTRNEYWDARFTFHSDPDKDMSDAEREINYFGFTVTSWQ
                     TDREIRGGE"
     gene            10397..11305
                     /gene="virB9"
                     /locus_tag="RN951_003895"
     CDS             10397..11305
                     /gene="virB9"
                     /locus_tag="RN951_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="HDX2528824.1"
                     /translation="MMKKLTFTALALMMCGAAWGAAIPQASRYDSRVQQVIYNPQNVT
                     VVNTKPGFMTTLVFDNDEAVISAKPGFDEAWEATPDANRVNVRPVALTQGAPGEDGNT
                     TQVVIPPNSRDWHTNMLVVTSKRLYNVELNVIDDKSAQQPAFQVSYRYPGEERDKASR
                     EATARQREWEQKQQQASVQKALNSAQTPRNWSYTKYPGKGSFNIVPDFAYDDGRFTFV
                     GFSPSKSIPSVTKELNGKEHAVNSSIQKKGDFTVLVIQEVTPRLVLRSGNAVVGLENS
                     GFGKVHAADGSTVSRQVERVEKPESN"
BASE COUNT         3104 a         2800 c         2707 g         2694 t
ORIGIN      
        1 tcaaaccacg ctgggatttt tcctcaagtt ataatcatca ccccgaaaat cattcggcat
       61 ttactcatta aatagtcacc ccataggcct gtacatgttc actcagaaat atacatcctt
      121 ttctctgtca taaaccctct gattaatcat aaataaatac ttgtgacacc aatctttttc
      181 cttaacggaa cgaattgttg tgtagaagga gataatatta tgtcaaaaaa atatcagcca
      241 ttgcttataa ctcattatat gtcaacatgg gtcactataa cggaagcagt tgagatcact
      301 accaaaacca taaaacaaaa aattactcct agcgatattt atcgtcatgc cttgagtggc
      361 aacatcctac tatcggtcta tttccagtct cctgtgatac ttaagaagat acaaactttt
      421 aatggaaaaa taaaattcag gcagtttgag ggagacctac ttgataaact atgcatgctt
      481 gacagggacg gttttattta tggtcaaaat ttaagactct gtacagaagc cagatatgtt
      541 tgtcctgtgc aacaaattat agataccccc ctgataggct atgaatatgt tttgattcag
      601 cgcatactgg cacgtgaact taaatttccc tccccaattg tgggggcaag aaaaactaac
      661 catggtatta tagtaagatt ttcagaggag ctttttcaaa ttttcgaaac gatgagttgg
      721 aaagaacgcg tagaaaaaca aatttccaga ctacctaaaa acacagcatt agatgtcata
      781 aaaaaactaa cagaagtgac gaccataaaa tataatcaca atgggtgctt tcctctttat
      841 acattaccgc ctgatgcctg ttttgttatt cgccacaccg aagtcgaaag actaattaat
      901 ttatacaaaa aaagggagag tcatcccatt tcaccttccc gtatgacaac accgttatca
      961 cgcctgtttt ggctggcctg caagcacaat gatactatca gcccactgct gaatcatccc
     1021 tataagctcc tttctatttt tgaacaatgg gcatcagacg atggcatcgg ggaaaaactg
     1081 gacgctgaaa cactgaaaaa tgcgctgaag cgtggttcgc catcttcgac atccttatcc
     1141 ggctaatacc atccccattt gtaatggccg acaaccctaa ataagggttt tgcatccctt
     1201 atttagggct caccagcttt ctctcaggct tccactgtgt ttttttattc tccggccacc
     1261 gtttatttca gtcacaggag gatatatgac atcttatcag ttactacgcc tcagacaggt
     1321 tgagcaaaaa acagggctga agcgttcaca gatatacctt tatatgaaag agggtgcatt
     1381 tccccgttca ataaaaatag gccctgctag tgttgcctgg ctcgagtctg agattgacga
     1441 gtggatcaac aaaaagttat ctgaccgata aagacgcaat gaggagaaga tgatgaacat
     1501 taatatccct gcactcataa acttcgatcc tgcaggtata aaaaaaagca cctgcatgta
     1561 tatttcagac ctgcccggta ttgtgctata tgaaactata ccattcactg aatattcagc
     1621 tgaattactg agcacttatt cagttaagga gtcaatttca tgcttccatc cctgaatcat
     1681 attatattaa ccgttgctct tcaggcgcta cgggaaggaa atattcatca ctgcgaaact
     1741 atgggattca cttacgatga aatgaatttg ctcggttgct tatcaataaa cgatcttatc
     1801 accctcagtc aggcaccttt accgcttgtc gatattacta tccgccatga tgtcctgcaa
     1861 aaattactgg catcatccca cgaggaaaac aggcgtcagg aacaactgaa cagagctgtc
     1921 aggctggggg gctcaatcgc actgatgaac cgttatttcg gggttggctc cagagaaacc
     1981 tgtgcacgcc gccggttact cggtgtctcc gttccaaacg ggagaacacc cattccggat
     2041 gaagaaaccg atgctgcaat ctggcatcag tggcaaaaat atcgggtcga aaacattgat
     2101 tccccggagg cgctggacgc catgatgcag gttacagaaa acctttcatc gtgtactgcc
     2161 ccctcgctga ccgttgtctg gaactgcatc acgcattgcg aaagaaagaa cacggtaagg
     2221 agaatacaac gtgccagatg aaatcgatcg cgatcaggcg tttaatgaac ggtgcctaga
     2281 agcactgatt gaacaaagcc ggttaagacc cacaccgaca ccttccctgc agcactgtcg
     2341 attttgcggc aaggctattc cggaaaaacg ccgtcagacg ctgccgggtg taacaacctg
     2401 tactgactgt cagtcgatac tggagaaacg cagacgttaa atctgtatgt gcggaggaga
     2461 atagctccgc acattttaat atgcaccagc cggcttgttt tcaggttccc gtgcctccat
     2521 gtcatggatg aataacctgc tcacatctcc tgctgtggca atcctttttt acagtcagta
     2581 caccagaggt cagacatgaa caaaccggca aacaagatgg aattcgtcag aaaactgcgg
     2641 taaataaatg acggcagcct gctggaaaag gttgtcgggc atatggaaga aaagctcaca
     2701 gggaatgagc ttgaaatgct ttatgccgca gcagattatc gccgcgcaga gattgtaata
     2761 aaccagtact ttgataaggt tcccggtaat gtctggaaat atgtcagata actctgtgtt
     2821 ttttatgcaa caggtacaga cggataccac tgcggcatga aaacgaattt caccacccgg
     2881 cccggtaagt atcggcctaa gtggccggga aacgtttaac cagattaaag accgtccctt
     2941 acaacaaaag ggactactgt attcctgtct ttcacgcctt acacattatt gtcgttacca
     3001 aattcagcca cagagacagc atacaacccc atctgacata taaagaaagt cttcctccgg
     3061 atgtttaatt taacctgata ataatcaaca aatattatta tcagcccgcc cgtcatcatt
     3121 catgcacaca cacaccgtgc cagtaatacg ttaatttcaa atactttttt atcattcctt
     3181 ccggtattta ttttcccgtt aaaatttcat tccccctcct gcatcctgac catgctcttt
     3241 aacaatatgg agcgggctgt cacacaacca taattcaggg tgccgctgaa tgttctcgct
     3301 gacccgttaa aaccggaatg caggatcgga atgtgatcga agagatcatc ttcaacaatt
     3361 ttaattaaac gaggacacta tgagaaagcc tgtttattac gcgtatgttg cccaggaaag
     3421 tcatccggac tctcagggtg agaaaaatac ctggtggaca aaggtcggag tcgcctttcc
     3481 ccaccacggt aaatccggtc tgaatattgt cctgacgccc ggtattgccg tttccggcaa
     3541 actggtcctg cttgagcccc gggaggaaaa taatccacca cagaatacgg gccccatcga
     3601 aaccgtgtcg taaccaccct taattctgtt cccacagcat gcagtatcag cagaccctgc
     3661 atgtcacttg tttactgagg tcaccatgct ttccaccaca gcctttctgg cgatagccat
     3721 gcagtgcgcc gccagcattc atccgtccac ggcattcgac gtggcacggg tggaatccgg
     3781 ttttaaccct tatgccatcg ctgagattgt cccgaaggcc ggcccctctt tcggcgatca
     3841 acacattatt tctcacctgc cagccagccg gggagatgca gagcatattc tccgccgcct
     3901 gacagcacag gatcgccgtt actctgtcgg gctgatgcaa atcaccagca ccaatttccg
     3961 ccattatggt gtgtccgcca cagagctact tgatccctgt accaatctgt ccgtcttcga
     4021 acacattctc agagactgct accggcgcgg cggcacgctg aaaagggcgc tgagttgtta
     4081 ttattccggc aatttcagta ccgggcaaca acctgaaacg gcgttttccg gaacgagcta
     4141 tatccagcga atcggttatc cgccgggatc atcccgctat gcggtccccg gaacccgtga
     4201 ggacaaatca tcagttgccg ttcccctgaa aaccgcccct gccagtgact catcccgtca
     4261 ccacgagatc tggcccggag tcgtcgtccg tggcgtccct gcgaaactcc gccaagaaaa
     4321 aatcttcatc gcaccgttct ccgcgccgtc agtgcgccgg agtttctccc tgtcaccccg
     4381 tgaggaggag gaataatgat acttttccgc aagctaaaag ctgtggtccc ccccgtttcg
     4441 gcctgtacgc tgacgacttt ttctgcaacc ccggcactgg ccgacggatt tcagcgggca
     4501 aatactgtca tgcaaaaagt gtcaaccggg ctgcatggtc tggcggcaat cacgatcacc
     4561 gtggccgtga tctggattgg ctataagacc ctgtggaaag gcgagagcct gtcgcagtgc
     4621 ggctacatca tcattggcgg cattttaatt ggcggaggca gtgaaatcgg cgctctgctg
     4681 atgagctaag aggctgaaca tatggcaaag ctgctcaagg caatgaaacg cccggcggcg
     4741 ctgtgggggg tgcctatggt gcccctgctg gctgtcacgg gtgtaaccat catcgttgct
     4801 gtctggactt ccgtcgcact cctgttctta cttcccgtcg aatttctggt gatgaaatcc
     4861 ctcaccagaa atgaaccaat gcggttcaat ctgattgccg tttggctgag agtgaaggga
     4921 aaaccggtag caaaccgttt atttggcgca acaacactta tgcccgttga gcatgaggct
     4981 gttgatatca aggagtttct cgacgccatg aaactaaatc agtgtgccac catcaagaag
     5041 tatattccgt actcatcgca cattcatcag catgtggttc gctcacctaa aagcgatctg
     5101 tactgcacct gggaattgat gggaacgccg ttcgactgcg agtctgacga atcactccag
     5161 ttcgggacga accagttaca cgggctaatc cactcattcg aaggtatgcc cgtcactttc
     5221 tatatccata acgaccgcaa tacgtttacc gacaatcttc ataaagattc cggcaacccg
     5281 tatgccgatg aagttagccg tctttactac gcttctgtcg gggtgttccg gcgtaaccgc
     5341 ctgttcctga cagtctgcta tcgcccgttt gtcagccttg aaaaagcaga acgcaaacgg
     5401 atgaaagaca gccagaaact aaaggaactg gacggtgctt tgctggaaat gctggaaata
     5461 aaaagcacgc tcgataccgc gctgtcgcgc tatggtgcgc ggcctctcgg tacgtttacc
     5521 gaaggaagcg cggtgttttc gtcgcaactg gctttctatg aatatctgtt aacgcaccag
     5581 tggcgaaagg tgcgcgtcac ccgcaccccg gcctatgacg tgatgggagc ggcggcgttg
     5641 ttcttttcgg ctgaatccgg gcagataaac cacgccaacg gtacgcaata tttccggggg
     5701 ctggaggtta aagagttctc cgaagaaacc gccacgggga tgatggactc ccttctttat
     5761 gccccctgcg attacgtgat cacgcagtcc tatacctgca tgtcacgcga ggaagcgaag
     5821 aaagccatta agcgtacccg tcgccttttg atgagtgccg atgacgatgc tgtttcccag
     5881 cggctggatc tggatgtggc gcttgacctg ctgacatcgg ggaaaatcgc ttacggaaag
     5941 caccattttt ccatcatggt gtattccccg tcgctggaaa acctagtggc tgatactaac
     6001 gaaatcagta atgcgctgaa caacatcggg ataacgcctg ttccggcaga aatatcgctt
     6061 tcagcggcgt atatggcgca actgccaggc aactacaacc tgcggccacg taaaggggag
     6121 ctaagtagcc aaaactttgt ggagctggcc gcactccata atttctatcc gggcaagcgc
     6181 gataaagccc cctgggggga tgctatggct ttactgcgca ccccgtcagg agatggctac
     6241 tatatcaacc tgcataacac actggcagat aaggacgaat tcaacgaaaa gaacccggcc
     6301 agtacctgca tcctcggtac gaacggttcg ggtaaaacca tgttgatgac gttctttgag
     6361 atcatgcagc agaaatacgg gcgtgaggat agcttctccc cggatgccaa aaccaaacgg
     6421 ctgacaaccg tttacctcga taaagaccgg ggcgcagaga tgaacatccg ggcgctgggt
     6481 ggccgttact atcgggttat cagtggtgag tctacagggt ggaacccgtt ctcgttgcca
     6541 gcaaccaaac gcaatatcaa tttcatcaag caactgatga aaatcctttg tacccgcaac
     6601 ggctcgacga tcttcccacg cgatgaacgc cgtctgagtg atgcggttaa tgctgtgatg
     6661 aatgacgagc cacaatatcg cgtctacggc attacccgaa tgctggagaa tttgcctgag
     6721 ccggctacga aagaagccca ggaaaacggc cttagcattc ggttgtcaca gtgggcgcag
     6781 ggcggtgagt tcggctgggt gtttgataac gagtctgaca cgttcgatat cagcaactgc
     6841 gataacttcg gcatcgacgg aacggagttc ctggacgatg caagcgtatg tgcgccaatc
     6901 tcgttttatc tgctgtaccg cattaccagc ctgcttgacg ggcgacgcct ggtcattttc
     6961 atggatgaat tctggaagtg gttacgcgac ccggtgttta aggactttgc ttataacaag
     7021 ctgaaaacca tccgtaagct gaacgggatg ctggtcgtcg gcactcaatc cccggctgag
     7081 atcatcaaag atgatatcgc cccggcagtg attgagcagt gcgggacaca gattctggcg
     7141 gcgaacccca acgccgaccg cgcacattat gttgacgaca tgaagtttga accggaagtg
     7201 ttcgacgtgg tgaaagggct tgacccgcaa gcccgccagt atgttgtggt gaaaaatcag
     7261 ttcaagcgcg gcgataccaa acgttttgcc gctcgtgtca cgctagacct gtcgggtatc
     7321 ggcagatata ccaaagtcat gagcggcgat gcccccaacc tcgaaatatt cgaatcgatt
     7381 taccgggaag gaatgcagcc tcatgaatgg ctcgatacct acctggctaa agcactctga
     7441 ttccaaagga gatataggat gaaaactcac ttttacgcgc taattttcgc atgttcgctt
     7501 gcaagccctc tggcacaagc gggaggtata ttagtatttg atgccacggc caaactggaa
     7561 aatgtccgcc agtggcagaa agaagcgaag caatggatgg agaccgcaca acactacaaa
     7621 gaccagatac gagcttataa agaccaactg gcaacagcca caggtgttcg agatatcgcc
     7681 agctttgttg accaagccaa aagcctgaaa gccgatctcg aaaaactacg caagccggga
     7741 caggctctga atgatttgct tctctccggc ggctcctccg ggcagttcga tgcgctgtac
     7801 gaaaaatata aaatttttga tacctgcaaa gccgaacgct cggagagtta tgccaacgtg
     7861 tgcaaacaac aggtcatcaa taaagctatc cagcttgagc agaccgacga gatccagaat
     7921 caggtaagcc aggccctggg agaaatcaac agcctctcca acagagttgc gctagccaaa
     7981 gattcgaaag aatctcaaga ccttgcaaac agtattcagc taaaatctgt catgctgaac
     8041 acgcttacca ctcagtggga aatgagtgtg aaagcagcag ataaacgcga aaaagtgctt
     8101 gaggcggagc gcgttaaaca gtggaaccaa cagcagttaa acgcgccaac tgctgacctt
     8161 aataatttat gaggttttta tgttatcaaa aaaaattatt ttaatttcga cgctcaccct
     8221 gtgtttttct gttattggat gcaaggagga agctaaaaca acaaaatggt ataaggaaca
     8281 ccctgatgaa ttaaaactcg tttatgaaaa gtgccaaaag agtggtgatg ctactgaaaa
     8341 ctgcaagaat gcaaatgaag cccactatca aataaagcag ctaaacgcac caactccaga
     8401 cttaaataat ttagaggagt aatatatgag tggcggtctt tttgttgggg ttgagaaata
     8461 cctaatagga ggaataacgg acgccacaaa aggattaatg atgtcgtact cttctatgat
     8521 gatggggctg gcagcagcgt cagctaccat ctacatcatg tggcgtggat accagactct
     8581 ggctggtaag ctctctacgc cgatggaaga cacgatgtgg gacatcatga ggatggcgat
     8641 catcctgtcc tttgtagcta atttaggtgg ctacctcgat ggcgttattg atgccataaa
     8701 cggaataaag gagggttttt ctggcagtga taatatatgg cagctattag acaccttatg
     8761 gaataaagca aaggtgttag gtaaaacatt acacgacatg gatgattcca cttatataaa
     8821 agatgaggga atgactgctc aattttatgt ctggcttggg atattcgtct taatgattat
     8881 caccgcgttt gtttccatga tagcggaagt catgatctta ttactgagta ttacagcacc
     8941 tatatttatt ttttgcctta tgtatggttt tctccgcacc atgttcaata actggctaca
     9001 aaatatattt gcagccatat taaccattat gctttcagct ctttctttaa gaattgtagt
     9061 gaattattta aacctagtcc ttaccaaggc aacgaaggtc gcggacagtt caacaattgt
     9121 tgaattagga gcacaagtct gtcttgcggg tatctgtgcg gcaatattgg tttatctctc
     9181 cgcaaaactg gccgcagcac tggccggggc gagtgctacc gtatccatgc aggggctggc
     9241 cgctgtaggt atcggtgctg ctgcttttgg tgccgggaag ctagccggag gtgcaattaa
     9301 agaaaccaaa cgttccaccc aggacaacat tcagggctgg aaggatgcga atgcaggtaa
     9361 gcccggcaag cctggaggtg agttaggcta taacgcttct aaagcgcgta aatacgcgat
     9421 tgagcagatg atagcccgga acgaagcgcg gaggctggca cagtcgagag aatccgcagt
     9481 taagaagttc aatagctaag acgtctccag tccatccccc caaagtgcca acttatgaaa
     9541 atataattat attttcatat ttttaattca attgaggaaa tatttgatga aacgcttgat
     9601 tgcgctggct ttgctatgcg cgctttctgg ctgcgcccag aacacgcttc catctgcatt
     9661 tagcggtaag ggagaacccg taaacacatc tcaaattatg gcggagttaa acagtcatga
     9721 atgaacagaa attaattgct gaatcccgca cctttgagca gcaaatgatt gaccgggata
     9781 aacgcgccac gaaagccggt tttgttgttg gcggtgtggg tctgctgatt gcggtactgg
     9841 cgctcgtcgc cgtggtcgtg atgttgccac taaaacagac agacgttgat ctgtataccg
     9901 tggataacca cacaggacgg gtggaacatg ttacccggac atcgaaaacc agcctgaccg
     9961 caacagaagc ctatcaaaag gcgatggccg caaactacgt caaagtacgt gagcggtatg
    10021 tctatccctc tttgcaggac gactacgaga cggtacaggt ctacaacgct ccccaggtaa
    10081 acgatgacta tctggcgctt tacgccggaa aaaacgcccc ggacaaggtt tataagaacg
    10141 gtgcgcacac cgtgaaagtg gagatcctgt ccaaccagat caccgatgga acagcccccg
    10201 ataaagtcgc cactgttcgc tacaagaaga ttatccgccg tctggctgat aacagcaccc
    10261 gcaacgagta ttgggatgcc cggttcacat tccattcaga ccctgacaag gacatgagcg
    10321 atgcggaacg cgagatcaac tacttcggct ttaccgtcac cagttggcag accgaccgcg
    10381 aaatccgggg aggtgaatga tgaaaaagtt aacgtttacc gcactggcac tgatgatgtg
    10441 cggcgcggca tggggtgcgg ccataccaca ggcaagccgc tatgactccc gtgttcagca
    10501 ggttatctat aaccctcaga acgtcaccgt cgttaacacc aaacccggct ttatgacaac
    10561 gctggtattt gataacgatg aggcggtcat aagcgccaaa cccggctttg atgaggcgtg
    10621 ggaagcaacg ccggatgcaa accgggtaaa cgttcgcccg gttgcgctca cgcagggagc
    10681 gcccggagaa gatggcaaca caacgcaggt cgtgatcccc ccgaacagcc gggactggca
    10741 taccaatatg ctggttgtca ccagtaagcg cctgtacaac gtcgagctga acgtcatcga
    10801 tgataaatcg gcacagcaac ccgcttttca ggtgagctat cgctatccgg gcgaagaacg
    10861 ggacaaagcg agccgggagg cgacggccag acagcgcgag tgggagcaga aacagcaaca
    10921 ggccagcgtc cagaaagcgc tgaactcggc gcagacgccc cgcaactgga gttacaccaa
    10981 atatccgggc aaaggcagtt tcaacatagt tcccgacttt gcttatgacg atggccgctt
    11041 tacgttcgtg ggcttctccc cgtctaagtc cattccttct gtcaccaaag agctgaacgg
    11101 caaagagcat gcggttaaca gcagtatcca gaagaaaggc gacttcaccg tactggtgat
    11161 tcaggaggtg acgccacgcc tggtactgcg ttccggtaat gccgttgtag gtctggaaaa
    11221 tagcggattt ggcaaggtac acgccgccga tggttccacc gtatcccggc aggtggaaag
    11281 agtggaaaaa ccggaatcca attaa
//
LOCUS       DAPOAV010000118        11270 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.118, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000118 DAPOAV010000000
VERSION     DAPOAV010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11270
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.118"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..893
                     /locus_tag="RN951_003896"
     CDS             <1..893
                     /locus_tag="RN951_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element IS600 family transposase"
                     /protein_id="HDX2528825.1"
                     /translation="VFCTGVAEKYALIEQWRQQFPIEAMCQVFGVSRSGYYNWVQHEP
                     SDRKQSDERLKLEIKVAHIRTRETYGTRQLQTELAENGIIVGRDRLARLRKELRLRCK
                     QKRKFRATTNSNHNLPVAPNLLNQTFAPTAPNQVWVADLTYVATQEGWLYLAGIKDVY
                     TCEIVGYAMGERMTKELTGKALFMALRSQRPPAGLIHHSDRGSQYCAYDYRVIQEQFG
                     LKTSMSRKGNCYDNAPMESFWGTLKNESLSHYRFNNRDEAISVIREYIEIFYNRQRRH
                     SRLGNISPAAFREKYHQMAA"
     gene            1047..3044
                     /gene="betT"
                     /locus_tag="RN951_003897"
     CDS             1047..3044
                     /gene="betT"
                     /locus_tag="RN951_003897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004119118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline BCCT transporter BetT"
                     /protein_id="HDX2528826.1"
                     /translation="MSENDTIPKKSTSQINKAVFFTSALLIFLLVAFAAVFPDVADKN
                     FKLLQQQIFTNASWFYILAVALILLSVTFLGLSRYGDIKLGPDHAQPDFSYHSWFAML
                     FSAGMGIGLMFFGVAEPVMHYLSPPVGTPETVAAAKEAMRLTFFHWGLHAWAIYAIVA
                     LILAFFSYRHGLPLTLRSALYPIIGDRIYGPVGHAVDIFAVIGTVFGVATSLGYGVLQ
                     VNAGLNHLFGVPINEMVQVILIVVITGLATISVVSGLDKGIRILSELNLGLALLLLAL
                     VLCLGPTVLLLKSFVENTGGYLSELVSKTFNLYAYEPKSSNWLGGWTLLYWGWWLSWS
                     PFVGMFIARVSRGRTIREFVTGVLFVPAGFTLMWMTVFGNSAIYLIMNQGATDLANTV
                     QQDVALALFNFLEHFPFSSVLSFIAMAMVIVFFVTSADSGAMVVDTLASGGVANTPVW
                     QRIFWASLMGIVAIALLLAGGLSALQTVTIASALPFSVILLISIYGLLKALRRDLTKR
                     ESLSMATIAPTAARNPIPWQRRLRNIAYLPKRSLVKRFMDDVIQPAMTLVQEELNKQG
                     TISHISDAVDDRIRLEVDLGNELNFIYEVRLRGYISPTFALAAMDNDEQQTEQHRYYR
                     AEVYLKEGGQNYDVMGWNQEQLINDILDQYEKHLHFLHLVR"
     gene            3107..4384
                     /locus_tag="RN951_003898"
     CDS             3107..4384
                     /locus_tag="RN951_003898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001505014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2254 domain-containing protein"
                     /protein_id="HDX2528827.1"
                     /translation="MISRWKWMLKQTIKKLWFRATLFAIVAIITALLSILFKSMIPES
                     VSVKVGAEAVDNILNILASSMLAVTTFSLSIMVTAYGSATTNVTPRATRLVVEDVTTQ
                     NVLATFIGSFLFSLVGIIALNMGAYGERGRVILFIVTLVVIALILITLLRWIQHLTSL
                     GRVGETTAQVEQAAIETFIARARNPCLGGYPWLENNEQPKGTVAVYPKKIGYVEYIDM
                     VKLSKLLTNDPRHVYLVAQPGSFIHPSMPVLYLSQGQESSISTDLLETIIVSDARSFA
                     QDPRFCLSVMAEIACRALSPAVNDPGTAIDVIGRGVRILSTYAQNKSDEIEVKYPSVH
                     VAPLQNNDLLEDFFSPVARDGASMREIQIRVLKGLSMLSKGWPGIFAEAAHTLAFETL
                     EHATRADHIDSDRYLIKSTYYNLFSGEYSNKKT"
     gene            4632..5288
                     /locus_tag="RN951_003899"
     CDS             4632..5288
                     /locus_tag="RN951_003899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDX2528828.1"
                     /translation="MTGENRGRGRPRKTESTYADTRNDLIRSGLELLTQNGFLATGVD
                     AIVKNANVPKGSFYYYFKSKEDYAQTVLNAYDSFFEHKLKKHLHESSCTPMVRLENFI
                     NDACEGIKKYNFTRGCLVGNMMQESPGLPQSFIKVLQNILESWQALVAACLSDALSSG
                     EISSNMNNTQLAAIFWSGWEGAVMRSKLYCSTEPVYDFWSYFKTSVRYQSSQEATTGQ
                     "
     gene            complement(5469..5597)
                     /locus_tag="RN951_003900"
     CDS             complement(5469..5597)
                     /locus_tag="RN951_003900"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HDX2528829.1"
                     /translation="MAQGMDLMGNMAPFILRGVTLKGIDSVMFAKEKRAAIWQQAV"
     gene            6568..6794
                     /locus_tag="RN951_003901"
                     /pseudo
     CDS             6568..6794
                     /locus_tag="RN951_003901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229544.1"
                     /note="with IlvB catalyzes the formation of 2-acetolactate
                     from pyruvate, the small subunit is required for full
                     activity and valine sensitivity; E.coli produces 3
                     isoenzymes of acetolactate synthase which differ in
                     specificity to substrates, valine sensitivity and affinity
                     for cofactors; also known as acetolactate synthase small
                     subunit; frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
     gene            complement(6796..7578)
                     /locus_tag="RN951_003902"
     CDS             complement(6796..7578)
                     /locus_tag="RN951_003902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HDX2528830.1"
                     /translation="METKQKERIRRLMELLKKTDRIHLKDAARMLEVSVMTIRRDLHQ
                     EDEPLPLTLLGGYIVMVNKPAPSMPVIHDVPKNHRDDLPIAILAAGMVNENDLIFFDN
                     GQEIPLVISMIPDAITFTGICYSHRVFVALNEKPNVTAILCGGTYRARSDAFYDASNS
                     SPLDSLNPRKIFISASGVHNHFGVSWFNPEDLATKRKAMNRGLRKILLARHALFDEVA
                     SASLAPISAFDVLISDRPLPADYVTHCQNGSVKIITPDSEDE"
     gene            7884..8804
                     /gene="rbsK"
                     /locus_tag="RN951_003903"
     CDS             7884..8804
                     /gene="rbsK"
                     /locus_tag="RN951_003903"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDX2528831.1"
                     /translation="MDIAVIGSNMVDLITYTNQMPKEGETLEAPAFKIGCGGKGANQA
                     VAAAKLNSKVLMLTKVGDDIFADNTIRNLESWGINTTYVEKVPCTSSGVAPIFVNANS
                     SNSILIIKGANKFLSPEDIDRAAEDLKKCKLIVLQLEVQLETVYHAIEFGKKNGIEVL
                     LNPAPALRELDMSYACKCDFFIPNETELEILTGMSVDTYDHIRLAARSLVDKGLNNII
                     VTMSEKGALWMTRDQEVHVPAFKVNAVDTSGAGDAFIGCFSHYYVQSGDVEAALKKAA
                     LFAAFSVTGKGTQSSYPSIEQFNEFLTLNE"
     gene            8832..10148
                     /gene="fucP"
                     /locus_tag="RN951_003904"
     CDS             8832..10148
                     /gene="fucP"
                     /locus_tag="RN951_003904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose:H+ symporter permease"
                     /protein_id="HDX2528832.1"
                     /translation="MNDKNIIQMPDGYLNKTPLFQFILLSCLFPLWGCAAALNDILIT
                     QFKSVFSLSNFASALVQSAFYGGYFLIAIPASLVIKKTSYKVAILIGLTLYIGGCTLF
                     FPASHMATYTMFLAAIFAIAIGLSFLETAANTYSSMIGPKAYATLRLNISQTFYPIGA
                     ASGILLGKYLVFSEGESLEKQMSGMNAEQIHNFKVLMLENTLEPYKYMIMILVVVMVL
                     FLLTRFPTCKVAQTSHHKRPSAMDTLRYLAKNSRFRRGIVAQFLYVGMQVAVWSFTIR
                     LALELGDINERDASNFMVYSFACFFIGKFIANILMTRFNPEKVLILYSVIGALFLAYV
                     ALAPSFSAVYVAVLVSVLFGPCWATIYAGTLDTVDNEHTEMAGAVIVMAIVGAAVVPA
                     IQGYIADMFHSLQLSFLVSMLCFVYVGVYFWRESKVRTALAEVTAS"
     gene            10160..11173
                     /locus_tag="RN951_003905"
     CDS             10160..11173
                     /locus_tag="RN951_003905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HDX2528833.1"
                     /translation="MSTRINLWRALFGEKPRILLENSDFTVTSFRYDSGVEGLKIANS
                     RGHLIILPWMGQMIWDAQFDGHSLTMCNMFRQPKPATEVIETYGCFAFHSGLLANGCP
                     SAEDTHLLHGEMACAAMDEAWMELEGDMLRLTGRYEYVMGFGHHYLAQPTVVLHKSST
                     LFDIKMAVTNLASVDMPLQYMCHMNYAYIPNATFSQNIPDEILRLRESVPSHVNPTAQ
                     WLAFNQRIMQGEASLSTLNQPEFYDPEIVFFADKLDAYTDQPEFRMISPDGTTFVTRF
                     SSAELNYVTRWILYNGEQQVAAFALPATCRPEGYLAAQRNGSLIQVAPQQTRTFTVTT
                     GIE"
BASE COUNT         2923 a         2485 c         2735 g         3127 t
ORIGIN      
        1 gcgtattttg cacaggagtc gctgaaaaat acgcgttaat cgaacaatgg cgacaacaat
       61 ttcccattga agcgatgtgt caggtatttg gtgtatccag gagcggttat tacaactggg
      121 tacagcatga accctcagac agaaaacaaa gtgatgagcg gctaaaactg gagattaagg
      181 tggcgcatat ccgcactcgc gaaacatatg gaacccggca gctccagacg gagctggcag
      241 agaatggcat catcgttggt cgtgaccgac tggcacgtct tcgtaaggag ctaaggctac
      301 gctgtaagca gaaacgcaag ttcagagcga ctacgaactc gaaccacaat ctgccagttg
      361 cgccaaatct gctgaaccag acgttcgctc ctacagcacc aaatcaggtc tgggtggcgg
      421 acctgacgta tgttgccaca caggagggat ggttgtacct cgctggcatc aaagatgttt
      481 atacgtgcga aattgtcggc tacgccatgg gagagcgcat gacaaaagag ctgacaggta
      541 aagccctgtt tatggcgctc aggagccagc gcccacctgc cgggctaatc caccactctg
      601 atcgaggttc acagtactgc gcatacgatt accgtgtcat acaggagcag tttggtctga
      661 aaacatcaat gtcgcgtaaa ggtaactgtt acgacaacgc tccgatggaa agcttctggg
      721 gaacgctgaa aaatgagagc ctgagccact atcgttttaa taaccgggat gaagccatct
      781 cagtaatacg ggaatacatt gagattttct acaatcgtca gcgtcgtcac tctcgtctgg
      841 ggaatatctc cccggcagcc ttcagggaaa aatatcatca gatggctgct taaaaaaaga
      901 acaaatggta gtgtccgcta ttgccagtac acctcaacat tccaccatgc attccgatta
      961 acgccgcata gccagttgaa ctttgctact ttgtgagagg tagtaccttc tatccagtgc
     1021 gaatttaatt aatggaataa atgattatga gtgaaaatga tacaatccca aagaagtcta
     1081 caagtcagat taacaaagcg gtattcttta catctgcttt gctaattttc cttcttgtcg
     1141 cctttgccgc cgtattcccg gatgtcgccg acaaaaattt taaactactt cagcaacaaa
     1201 tcttcacgaa tgccagctgg ttctacatcc ttgctgtggc cctgatttta ctgagtgtca
     1261 cgttccttgg actctcacgc tacggtgata tcaagctggg cccggaccat gcgcagcctg
     1321 atttcagcta ccactcctgg tttgcgatgc ttttttcggc agggatgggg atcggcctga
     1381 tgttctttgg cgttgccgaa cctgtaatgc attatctttc gccacccgtt ggcactccag
     1441 aaaccgttgc ggcagctaag gaagcaatgc gtctgacctt tttccactgg ggactgcacg
     1501 catgggcaat ttatgccatt gtggcgctga ttctggcgtt cttcagttac cgtcacggtc
     1561 tgcctttaac tctgcgctcc gcactctatc ccattattgg cgatcgcata tacggacctg
     1621 taggacatgc ggttgatatt ttcgctgtta taggcacggt ctttggcgtt gcgacatcac
     1681 tgggttacgg tgttttgcag gtgaatgccg gtttgaacca tcttttcggg gtgcccatca
     1741 atgaaatggt gcaggtaatt ctgatcgtgg tcatcacggg gttagcgacg atttcagtgg
     1801 tgtccggtct ggataaggga atacgtatcc tgtctgaact caatctgggt ctggctttgt
     1861 tgctcctggc gctggtcctg tgtctgggac caaccgtgct tctgctgaag tcatttgtgg
     1921 aaaatacggg cggttatctt tcggaactgg tgagtaaaac gttcaacctt tacgcgtatg
     1981 agcccaagtc gagcaactgg ctggggggct ggacattact gtactgggga tggtggcttt
     2041 catggtcgcc gtttgtgggg atgttcatcg cacgggtctc ccgcgggcga accattcgcg
     2101 agtttgtcac cggcgtgctg tttgttcccg cgggttttac gctaatgtgg atgacggtgt
     2161 ttggtaacag cgcgatctat ctcattatga accagggggc cacagacctc gccaatactg
     2221 ttcagcagga tgtggcgctg gccctgttta atttcctgga gcatttcccg ttctcttctg
     2281 tgctgtcatt cattgcaatg gcgatggtca tcgtcttctt tgtaacgtct gctgattcgg
     2341 gggcaatggt tgtggatact ctggcatcag gtggagtggc aaacacaccc gtctggcagc
     2401 gaatattctg ggcctcgctc atgggcattg ttgcaattgc gcttctcctt gccggagggc
     2461 taagtgcgct gcaaacggtg acaatagcga gtgcattgcc cttctcagtg atcttactaa
     2521 tatctatata cggactttta aaagctttgc gccgggattt gaccaagcgt gaaagcctga
     2581 gcatggcgac aattgctcct acggctgcac gtaacccaat tccttggcag agaaggttac
     2641 gcaatatcgc gtatctgccg aagcgatctc ttgtgaaacg ttttatggac gacgttatcc
     2701 agcccgccat gacgctggtt caggaggaac tgaacaagca ggggacgata agccacatta
     2761 gtgatgcagt cgacgatcgt attcgtcttg aagtcgattt gggcaacgag ctgaatttta
     2821 tatatgaagt gaggcttcgc gggtatatct caccgacctt cgcgctcgcc gcaatggata
     2881 atgatgagca gcagactgaa caacatcgat attatcgcgc tgaggtttat ctcaaagaag
     2941 gcggtcaaaa ttatgatgtg atgggctgga accaggaaca gctgattaat gacatactgg
     3001 accagtacga aaaacacctg cacttcctgc acctggttcg ttaatagcaa catgccgtcc
     3061 tgggggcggc aattattatc ccggccgcaa tatgagggaa tgcagaatga tttcacgctg
     3121 gaaatggatg ctgaagcaga caattaaaaa actatggttc agggcaacgt tattcgcaat
     3181 tgtcgcgata ataacggccc ttttatcaat tctttttaaa tcaatgatac ctgagtcggt
     3241 ttccgtgaag gttggtgcgg aagcagtcga taacattctg aacatactgg catcgagtat
     3301 gctggcagtg accacatttt cgctgagtat catggtcaca gcctacggtt cagccactac
     3361 taatgtgact cccagagcta cgcgtttagt tgttgaagac gtcaccacac aaaatgtact
     3421 ggccaccttc atcggttctt ttctcttcag tctggtaggg attattgccc tcaatatggg
     3481 agcttatgga gaaaggggga gagtcatttt attcattgtc acactggttg tcattgcctt
     3541 aatcctcatc acattgcttc gctggataca gcatttgacc tctctgggga gggttggtga
     3601 gacaacggca caagtagaac aggcggccat cgaaacattt attgcgagag caagaaatcc
     3661 ctgtctcggc ggatatccat ggcttgagaa caatgaacag ccgaaaggaa cggttgcagt
     3721 ttatccgaag aagattggct atgttgaata tattgatatg gtgaaactta gcaagctgct
     3781 gaccaatgat ccccgtcatg tatacctcgt ggcgcagcca ggcagtttca tacatccgtc
     3841 catgccagtt ttgtacctga gtcagggcca ggagtcgtca atcagcaccg atttacttga
     3901 gacgattatt gtctcggatg cacgttcatt tgctcaggat cctcgatttt gtcttagcgt
     3961 catggccgaa atagcctgcc gggccctttc ccctgcagtg aacgatcctg gaaccgccat
     4021 tgatgtcatt ggcagaggtg ttcgtatact ttccacttac gcgcagaata aatctgatga
     4081 aatagaagtg aaatatcctt cagtacatgt tgcaccactt cagaataacg atctactgga
     4141 agactttttc tcacctgtcg cgcgcgatgg tgccagtatg agggagattc agataagagt
     4201 ccttaaagga ctgtcgatgc tgagtaaagg ttggccaggg atatttgctg aagccgcaca
     4261 taccctggca tttgaaacat tagagcatgc aactcgtgct gaccatatag attctgatag
     4321 atatctaata aaatcaactt attataattt atttagtggc gaatattcta ataaaaaaac
     4381 atagctgcag agcaagcgat tcggttgttg gcaagtcaag ggcaaagcat tcgcgtgaga
     4441 atgggcgtat gctttgtgcc aaaagcaaac gttgctaatt ctgcactgtt cagcgatggc
     4501 gcagtagcga caggcactgc cactgtccag tcggcaaaag cgaacacttt gccactgcgg
     4561 ggataaactg attgaagctc tcgcgcaaaa tcacttattc ttttgcgtta ataaaatgta
     4621 ggagatgggt catgacaggc gaaaatcgtg gccggggaag gccgcgaaag acagaaagta
     4681 cctatgcaga tactcgtaat gatctgatcc gcagtggcct tgaactgctg acgcagaatg
     4741 gttttcttgc gacgggagtc gatgccattg ttaaaaatgc caatgtccct aaaggctcat
     4801 tttattacta ctttaagagt aaagaggatt atgctcagac cgttctgaac gcctatgaca
     4861 gtttcttcga gcataaactc aaaaaacatc tacatgaatc atcctgcaca ccaatggtac
     4921 gtctggaaaa tttcatcaat gatgcctgtg aggggattaa aaaatacaat tttacccgcg
     4981 gctgcctggt tggaaatatg atgcaggaga gtccggggct tccccaatcc ttcattaaag
     5041 tactacagaa tattcttgag agctggcagg cacttgttgc ggcctgcctg tccgacgcgt
     5101 tatcttcagg cgaaataagt tcaaatatga ataatacaca actggcggct attttctgga
     5161 gtggctggga aggtgcggta atgcgttcca aactatattg ttctactgag ccagtgtacg
     5221 acttctggag ctatttcaaa acctcggtac gctatcagtc ttctcaggaa gcaacaactg
     5281 gccagtaaaa ggggccgcag cccctaaaac ttattatact aagcctgagc tcggcatcca
     5341 tctaattagc tatattgaat gactgcacga ccgcgaattc cgccactcag aagtttttca
     5401 gccacagtga tggcgtcact gagcggataa acggtagtga gactatccat tctggactct
     5461 ggcaaatact ataccgcctg ttgccagatt gctgctcttt tctctttcgc gaacatgacg
     5521 ctatcaatcc ctttcagcgt gacaccacgc agaataaacg gagccatatt gcccatcaaa
     5581 tccatcccct gagccatgcc gcaggctgca acaatactgc catatcggac cccggcgcag
     5641 gcatttctcc agtaacaggg ggttgtattg tatttttttg tgccggttca ggtgtgcgtt
     5701 tcccggcgcg tctgcaccgg cttaaccaaa ttcaacaggg ataaaatagt gcaaataacc
     5761 gaagtattac ttgcagaatc gggggaagca tccggggttt tattcaacag gctgtagatc
     5821 actgactgcg tctgttggcc gtccacttca cgcgtcattc gaccagagta aatattgatg
     5881 attactagat tcgtgtattt tatcaggcat tttacttgcg aataaatccc cttactatcc
     5941 agcgaaacca cacaggtagc tattaccata tgtggtaata cactagttac aggaaaaata
     6001 tgcaagttcc gcaatacgtt gtgtgttgct ccttagccag gatcttttct tccatgcgag
     6061 atatgacaac aattttgagg aaggatgttc gtaactggta gagttactac aacaagcatg
     6121 ggaggctctg actctggcag acattgtact gtggaatgtt gttacaggtt ggggcggcaa
     6181 ccgtgccagg agaccatgag ccgttcacgg cattaaaggc cacacttcag tcgtttacat
     6241 tccctatggt ggcaggcatc ttccattaag gcgtcagagc gttaccaacg ttatgttgtc
     6301 atggctcatc tttcatagtc gatgcttatc tggtggctga agctagccgc agataaagag
     6361 tgtgaagttg ataccatgga gtggagtgac gtgcaggcag gagattcgct ctatgcaggg
     6421 ttgtgagatg aattcaaacc ggctggcagc gccagtgata ttcgaagatt cgtccggttg
     6481 ttacccagta tgcattaaaa acccagacat tatggacaat ataacggctt ctacaacaag
     6541 gaagtgcctg tttaccatcc gggtgtaatg actcaccttt gtgggctttt gcccgtcgcg
     6601 ctcttaacgt tgaagacatt ctctgcctgc cgattcagga ctgcgacaaa agccatatct
     6661 ggctactggt caaggatgac cagcgtctgg agtaggtgat aagccaaata gataagctgg
     6721 aatatgtggt gaaagtgcaa cgtaatcagt ccaatccgac gatgtttaac aagattgtgg
     6781 tgttttttca gtaagtcatt cgtcttctga atcaggtgta atgatcttta cagaaccatt
     6841 ctggcagtgc gtaacataat ctgccggtaa cggacgatcg ctaatcagaa cgtcaaatgc
     6901 agagatcggt gcaaggctgg cagaggccac ttcatcgaac aacgcgtggc gggcgagcaa
     6961 aattttccgt agtccacggt tcatcgcttt acgcttagtg gcaagatctt cagggttaaa
     7021 ccagctgacg ccaaagtgat tatgcacacc gctggcggaa ataaatattt ttcgcggatt
     7081 gagagagtct aatggcgaag agttactggc atcgtaaaaa gcatcacttc tggcacgata
     7141 cgtaccacca caaagtattg ctgttacatt aggcttttca ttcaacgcaa caaagacgcg
     7201 atgtgagtaa cagatgccgg tgaaggtgat tgcatccggg atcatgctta taacgagtgg
     7261 tatctcctgg ccattatcaa agaagatcag atcattttca ttaaccattc cggcagccag
     7321 aattgcaata ggtaagtcat cacgatgatt ttttggaacg tcatggatta ctggcatgga
     7381 tggcgcgggt ttattcacca ttacaatata gccacccagt agggtcagtg gcagaggttc
     7441 atcttcctga tggagatcgc gacgaatagt cattacagaa acttccagca ttcgcgctgc
     7501 gtctttcaaa tggattctgt cggttttctt aagcagttcc atcaaacgtc ggatacgctc
     7561 tttttgcttc gtttccatca actctctctc cgtaagaatg ttataaaaat aacattttgg
     7621 cgttagtaaa cattgttttc attaccatac tatacgaccg cccctttgaa atgaaaaggg
     7681 tataggctgc tgagttttgg gcactaatct tgttaggttg cttatgatta gatagtgttg
     7741 gcctgagtga tgagactgga agtctattaa ataaacatcg ggttgatgtg ctaatcgcga
     7801 tctcagtcac aaatgatgca aaagtaacat gctaatgtta tttaaatacc attgttatgc
     7861 gaaagtttat aagaggtagt gaaatggaca ttgcagttat tggttccaat atggtggatc
     7921 tcattactta cactaatcag atgcctaaag aaggagaaac tctggaagca cctgccttca
     7981 aaatcggatg tggtgggaaa ggtgctaatc aagcggtggc ggcggctaaa ttgaattcaa
     8041 aagtcctgat gctgactaaa gtaggtgatg atatttttgc ggataatact attcgtaatc
     8101 ttgaatcatg gggaattaat accacttatg ttgagaaggt cccctgtacc agcagtggtg
     8161 ttgcaccgat ctttgttaat gccaactcga gcaatagtat attaataatt aagggagcga
     8221 ataaatttct ttccccggaa gatatcgatc gagctgcaga agatctgaaa aaatgcaaat
     8281 tgatcgtttt acaactggaa gttcaactgg aaacagttta ccacgcgatt gagtttggta
     8341 agaaaaatgg tattgaagtg ttattaaatc cggctccggc attgcgtgag ttagatatgt
     8401 cttatgcctg caaatgtgat ttctttatcc cgaatgaaac agaactggaa atattaaccg
     8461 gtatgtcggt tgatacttat gatcatattc gtttggccgc acgttcgtta gttgataaag
     8521 ggctgaacaa tattattgtt accatgagcg aaaaaggcgc attatggatg acccgcgatc
     8581 aggaagtcca tgttcctgca ttcaaagtaa atgctgttga tactagtggc gctggtgacg
     8641 catttattgg ttgcttttcc cattattatg ttcaaagcgg tgatgttgaa gccgctttga
     8701 aaaaagccgc tctctttgcc gctttcagcg tcacagggaa aggtacgcaa tcatcttatc
     8761 cgagtattga acaatttaat gaatttttaa ccttaaacga ataatcatcc tgcacagtta
     8821 aaggtagcac tatgaacgat aaaaacatca ttcagatgcc tgatggatat ctgaataaga
     8881 ctcccttgtt ccagtttatt ttgttatcgt gtttattccc gctatgggga tgcgcagctg
     8941 cattaaatga catattaatc actcaattca aaagtgtatt ttcgctaagt aactttgctt
     9001 cagcattggt gcagagcgca ttttatggag gttatttttt aattgcaata ccagcatccc
     9061 ttgtgattaa aaagaccagt tataaggtgg caattttaat tggcctgacg ctgtatattg
     9121 gtggttgtac actttttttc cctgcctcgc atatggcaac ctacactatg ttccttgcag
     9181 ctatttttgc gattgcgatt ggcctgagtt tccttgaaac tgcagcgaac acatacagtt
     9241 caatgatcgg tccaaaagcc tatgccacat tgcggctcaa tatcagccag accttttatc
     9301 cgattggtgc tgcgtctggt attttattgg gcaaatatct ggttttctcc gagggggaaa
     9361 gccttgagaa gcagatgtcc ggaatgaacg ccgagcaaat tcacaacttt aaggtgctga
     9421 tgttagagaa cacccttgaa ccgtataagt atatgattat gattctggtt gtggtcatgg
     9481 tgttgttcct tttaacccgc ttcccaacct gtaaagtggc acagacaagt caccataaac
     9541 gcccgtcagc aatggatacg ctgcgctatc tggctaaaaa ttcgcgcttt cgtcgtggta
     9601 ttgtggctca attcctttat gtgggtatgc aggtcgcagt atggtcattt accatccgtc
     9661 tggcactgga gttgggcgat atcaacgaac gtgatgcttc aaacttcatg gtctatagct
     9721 ttgcctgctt ctttattggc aagtttatag ccaacatcct tatgacgcgt tttaatccgg
     9781 aaaaagtatt gattctctat tccgttatag gggcgctgtt cctggcatat gttgcactgg
     9841 ctccaagttt cagcgcggtc tatgtcgccg tcctggtaag tgttttgttt ggcccttgct
     9901 gggcgacgat ctatgcagga acactggata cagttgataa cgaacataca gaaatggcag
     9961 gagcagtcat tgttatggct attgtcggcg ccgcggtggt tccggcaatt cagggatata
    10021 ttgcagatat gttccactca cttcagcttt cattcctggt ttctatgctc tgctttgtct
    10081 atgtcggagt ctacttctgg cgtgaaagca aagtacgtac cgcactggct gaagtcacag
    10141 cgtcctgagg agaaccgtta tgagtacgcg tattaatttg tggcgggcgc tttttggcga
    10201 aaaacctcgt atcttgctgg aaaatagtga ttttactgtc acgtcttttc gctatgacag
    10261 tggtgtcgag gggcttaaaa ttgcaaacag tcgtggacat ttaattattc ttccctggat
    10321 ggggcagatg atttgggatg cgcaatttga tggacacagt ctcaccatgt gcaatatgtt
    10381 tcgccagcct aaaccggcga cagaggtgat agagacctat ggctgttttg cctttcattc
    10441 aggtttgctg gctaatggct gcccatctgc ggaagatact catctgctac acggtgaaat
    10501 ggcctgtgcc gcgatggatg aagcatggat ggaattagag ggagatatgt tacgccttac
    10561 cgggcgttac gagtatgtaa tggggttcgg gcatcattat ctggctcagc caacagtggt
    10621 ccttcacaaa tcctctacat tgttcgatat taagatggcc gtaaccaatc tggcttctgt
    10681 agatatgcca ctacaatata tgtgccacat gaattatgca tatataccaa atgctacgtt
    10741 cagccagaat ataccggacg aaatattaag gttgcgtgaa tcagtacctt cgcatgttaa
    10801 tcccaccgct cagtggctgg cgtttaatca acggattatg cagggagaag cctctctgtc
    10861 gacgctgaat caaccggaat tttatgatcc agaaatagtc ttctttgcag acaaactgga
    10921 tgcttacaca gatcagccag agtttcgcat gatctctccc gatggcacca cgtttgttac
    10981 tcgtttctcc agtgctgaac taaattatgt gacacgctgg atcctttata atggagagca
    11041 acaggtagcc gcctttgcat tacctgcaac ctgtcggcct gaggggtatc ttgccgcgca
    11101 acgtaatggc tcgctgattc aggttgcacc gcagcaaacg cgcactttta cagtcaccac
    11161 aggaattgaa taaccactta aggcctgaac agcggcgcgc ttatcgttaa ggtaagcgcg
    11221 tttttttacc cgccaggaca agactatgat agcgttgccc ttatagacga
//
LOCUS       DAPOAV010000119        11269 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.119, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000119 DAPOAV010000000
VERSION     DAPOAV010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11269
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.119"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            1..324
                     /locus_tag="RN951_003906"
     CDS             1..324
                     /locus_tag="RN951_003906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001442732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1889 family protein"
                     /protein_id="HDX2528834.1"
                     /translation="MVNFKDKNMPAVIDKALDFIGAMDVSAPTPSSMNESTAKGIFKY
                     LKELGVPASAADITARADQEGWNPGFTEKMVGWAKKMETGERSVIKNPEYFSTYMQEE
                     LKALV"
     gene            complement(444..623)
                     /locus_tag="RN951_003907"
     CDS             complement(444..623)
                     /locus_tag="RN951_003907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaH family protein"
                     /protein_id="HDX2528835.1"
                     /translation="MFAGLPSLTHEQQQKAVERIQELMAQGMSSGQAIALVAEELRAN
                     HSGERIVARFEDEDE"
     gene            697..2058
                     /gene="pabB"
                     /locus_tag="RN951_003908"
     CDS             697..2058
                     /gene="pabB"
                     /locus_tag="RN951_003908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 1"
                     /protein_id="HDX2528836.1"
                     /translation="MKTLSPAVITLPWRQDAAEFYFSRLSHLPWAMLLHSGYADHPYS
                     RFDIVVAEPICTLTTFGKETVVSESEKRTTTTDDPLQVLQQVLDRADIRPTHNEDLPF
                     QGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTVSLLSHNDV
                     NARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRF
                     HATYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGT
                     LPRLPDPQEDSKQAVKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPF
                     PAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCG
                     SIGYLSFCGNMDTSITIRTLTAINGQIFCSAGGGIVADSQEEAEYQETFDKVNRILKQ
                     LEK"
     gene            2062..2640
                     /locus_tag="RN951_003909"
     CDS             2062..2640
                     /locus_tag="RN951_003909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HDX2528837.1"
                     /translation="MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQP
                     GLLLTQRSIHLRKHAGQVAFPGGAVDDTDASAIAAALREAEEEVAIPPSAVEVIGVLP
                     PVDSVTGYQVTPVVGIIPPDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDS
                     HRVWLSWYEQYFVWGMTAGIIRELALQIGVKP"
     gene            2824..4188
                     /gene="sdaA"
                     /locus_tag="RN951_003910"
     CDS             2824..4188
                     /gene="sdaA"
                     /locus_tag="RN951_003910"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HDX2528838.1"
                     /translation="MISLFDMFKVGIGPSSSHTVGPMKAGKQFVDDLVEKGLLDSVTR
                     VAVDVYGSLSLTGKGHHTDIAIIMGLAGNEPATVDIDSIPGFIRDVEERERLLLAQGR
                     HEVDFPRDNGMRFHNGNLPLHENGMQIHAYNGDEVVYSKTYYSIGGGFIVDEEHFGQD
                     AANEVSVPYPFKSATELLAYCNETGYSLSGLAMQNELALHSKKEIDEYFAHVWQTMQA
                     CIDRGMNTEGVLPGPLRVPRRASALRRMLVSSDKLSNDPMNVIDWVNMFALAVNEENA
                     AGGRVVTAPTNGACGIVPAVLAYYDHFIESVSPDIYTRYFMAAGAIGALYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGGSPEQVCVAAEIGMEHNLGLTCDPVAGQVQVPC
                     IERNAIASVKAINAARMALRRTSAPRVSLDKVIETMYETGKDMNAKYRETSRGGLAIK
                     VQCD"
     gene            4319..5913
                     /locus_tag="RN951_003911"
                     /pseudo
     CDS             4319..5913
                     /locus_tag="RN951_003911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416329.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            complement(5917..7473)
                     /gene="yoaE"
                     /locus_tag="RN951_003912"
     CDS             complement(5917..7473)
                     /gene="yoaE"
                     /locus_tag="RN951_003912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family cation transport protein YoaE"
                     /protein_id="HDX2528839.1"
                     /translation="MEFLMDPSIWAGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRD
                     KARLLGLSLALIMRLGLLSLISWMVTLTKPLFTVMDFSFSGRDLIMLFGGIFLLFKAT
                     TELHERLENRDHDSGHGKGYASFWVVVTQIVILDAVFSLDAVITAVGMVNHLPVMMAA
                     VVIAMAVMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAI
                     GFSIIIEVFNQIARRNFIRHQSTLPLRARTADAILRLMGGKRQANVQHDADNPMPMPI
                     PEGAFAEEERYMINGVLTLASRSLRGIMTPRGEISWVDANLGVDEIREQLLSSPHSLF
                     PVCRGELDEIIGIVRAKELLVALEEGVDVAAIASASPAIIVPETLDPINLLGVLRRAR
                     GSFVIVTNEFGVVQGLVTPLDVLEAIAGEFPDADETPEIITDGDGWLVKGGTDLHALQ
                     QALDVEHLADDDDIATVAGLVISANGHIPRVGDVIDVGPLHITIIEANDYRVDLVRIV
                     KEQPAHDEDE"
     gene            7936..8907
                     /gene="manX"
                     /locus_tag="RN951_003913"
     CDS             7936..8907
                     /gene="manX"
                     /locus_tag="RN951_003913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HDX2528840.1"
                     /translation="MTIAIVIGTHGWAAEQLLKTAEMLLGEQENVGWIDFVPGENAET
                     LIEKYNAQLAKLDTTKGVLFLVDTWGGSPFNAASRIVVDKEHYEVIAGVNIPMLVETL
                     MARDDDPSFDELVALAVETGREGVKALKAKPVEKAAPAPAAAAPKAAPTPAKPMGPND
                     YMVIGLARIDDRLIHGQVATRWTKETNVSRIIVVSDEVAADTVRKTLLTQVAPPGVTA
                     HVVDVAKMIRVYNNPKYAGERVMLLFTNPTDVERLVEGGVKITSVNVGGMAFRQGKTQ
                     VNNAVSVDEKDIEAFKKLNARGIELEVRKVSTDPKLKMMDLISKIDK"
     gene            8970..9770
                     /gene="manY"
                     /locus_tag="RN951_003914"
     CDS             8970..9770
                     /gene="manY"
                     /locus_tag="RN951_003914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HDX2528841.1"
                     /translation="MEITTLQIVLVFIVACIAGMGSILDEFQFHRPLIACTLVGIVLG
                     DMKTGIIIGGTLEMIALGWMNIGAAVAPDAALASIISTILVIAGHQSIGAGIALAIPL
                     AAAGQVLTIIVRTITVAFQHAADKAADNGNLTAISWIHVSSLFLQAMRVAIPAVIVAL
                     SVGTSEVQNMLNAIPEVVTNGLNIAGGMIVVVGYAMVINMMRAGYLMPFFYLGFVTAA
                     FTNFNLVALGVIGTVMAVLYIQLSPKYNRVAGAPAQAAGNNDLDNELD"
     gene            9783..10634
                     /gene="manZ"
                     /locus_tag="RN951_003915"
     CDS             9783..10634
                     /gene="manZ"
                     /locus_tag="RN951_003915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020804907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IID"
                     /protein_id="HDX2528842.1"
                     /translation="MVDTTQTTTEKKLTQSDIRGVFLRSNLFQGSWNFERMQALGFCF
                     SMVPAIRRLYPENNEARKQAIRRHLEFFNTQPFVAAPILGVTLALEEQRANGAEIDDG
                     AINGIKVGLMGPLAGVGDPIFWGTVRPVFAALGAGIAMSGSLLGPLLFFILFNLVRLA
                     TRYYGVAYGYSKGIDIVKDMGGGFLQKLTEGASILGLFVMGALVNKWTHVNIPLVVSR
                     ITDQTGKEHVTTVQTILDQLMPGLVPLLLTFACMWLLRKKVNPLWIIVGFFVIGIAGY
                     ACGLLGL"
     gene            10689..11147
                     /locus_tag="RN951_003916"
     CDS             10689..11147
                     /locus_tag="RN951_003916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF986 domain-containing protein"
                     /protein_id="HDX2528843.1"
                     /translation="MTITDLVLILFIAALLAFAIYDQFIMPRRNGPTLLAIPLLRRGR
                     IDSVIFVGLIVILIYNNVTNHGALITTWLLSALALMGFYIFWIRVPKIIFKQKGFFFA
                     NVWIEYSRIKAMNLSEDGVLVMQLEQRRLLIRVRNIDDLEKIYKLLVSTQ"
BASE COUNT         2754 a         2841 c         2846 g         2828 t
ORIGIN      
        1 atggttaatt ttaaggataa gaatatgcct gctgtaatag ataaagccct ggatttcatt
       61 ggtgccatgg atgtatcagc gccaacacca agttcgatga atgaaagcac ggcgaaggga
      121 atctttaaat atttaaaaga actgggagta cccgcgagtg ccgctgatat tacggcgcga
      181 gctgaccagg aaggctggaa ccctgggttc acggaaaaaa tggttggatg ggcaaaaaaa
      241 atggagacag gtgaacgttc tgtgattaaa aatcctgaat acttttcaac atatatgcag
      301 gaagaactaa aagcactggt ctgagttaaa tttatatcag cataaatggg tcaggacgct
      361 tttaatcaca tataaaaagc gtcctttttc tcacaatcaa atgatcatcg gcttctataa
      421 cgaaatcgat acggattagt gtgttactcg tcttcatcct caaaacgcgc cacgattcgc
      481 tcgccggagt ggttggcacg cagctcttct gccaccagcg cgattgcctg gccgctgctc
      541 atcccttgtg ccatcagttc ctggatccgc tcgacagctt tttgctgctg ttcatgggtg
      601 agtgaaggta aacctgcaaa cattgttaac tcctgctaaa ttgttggcgc taattatttc
      661 atgctacccg gcacatagcc agtagagtca ggactgatga agacgttatc tcccgctgtg
      721 attactttac cctggcgtca ggacgccgct gaattttatt tctcccgctt aagccacctg
      781 ccgtgggcga tgcttttaca ctccggctat gccgatcatc cgtatagccg ctttgatatt
      841 gtggtcgccg agccgatttg cactttaacc actttcggta aagaaaccgt tgttagtgaa
      901 agcgaaaaac gcacaacgac cactgatgac ccgctacagg tgctccagca ggtgctggat
      961 cgcgcagaca ttcgcccaac gcataacgaa gatttgccat ttcagggcgg cgcactgggg
     1021 ttgtttggct acgatctggg ccgccgtttt gagtcactgc cagaaattgc ggaacaagat
     1081 atcgttctgc cggatatggc agtgggtatc tacgattggg cgctcattgt cgaccaccag
     1141 cgtcatacag tttctttgct gagtcataat gatgtcaatg cccgtcgggc ctggctggaa
     1201 agccagcaat tctcgccgca ggaagatttc acgctcactt ccgactggca atccaatatg
     1261 acccgcgagc agtacggcga aaaatttcgc caggtacagg aatatctgca cagcggtgat
     1321 tgctatcagg tgaatctcgc ccaacgtttt catgcgacct attctggcga tgaatggcag
     1381 gcattccttc agcttaatca ggccaaccgc gcgccattta gcgctttttt acgtcttgaa
     1441 cagggtgcaa ttttaagcct ttcgccagag cggtttattc tttgtgataa tagtgaaatc
     1501 cagacccgcc cgattaaagg cacgctacca cgcctgcccg atcctcagga agatagcaaa
     1561 caagcagtaa aactggcgaa ctcagcgaaa gatcgtgccg aaaatctgat gattgtcgat
     1621 ttaatgcgta atgatatcgg tcgtgttgcc gtagcaggtt cggtaaaagt accagagctg
     1681 ttcgtggtgg aacccttccc tgccgtgcat catctggtca gcaccataac ggcgcaacta
     1741 ccagaacagt tacacgccag cgatctgctg cgcgcagctt ttcctggtgg ctcaataacc
     1801 ggggctccga aagtacgggc tatggaaatt atcgacgaac tggaaccgca gcgacgcaat
     1861 gcctggtgcg gcagcattgg ctatttgagc ttttgcggca acatggatac cagtattact
     1921 atccgcacgc tgactgccat taacggacaa attttctgct ctgcgggcgg tggaattgtc
     1981 gccgatagcc aggaagaagc ggaatatcag gaaacttttg ataaagttaa tcgtatcctg
     2041 aagcaactgg agaagtaaga cgtggaatac cgtagcctga cgcttgatga ttttttatcg
     2101 cgctttcaac ttttgcgccc gcaaattaac cgggaaaccc taaatcatcg tcaggctgct
     2161 gtgttaatcc ccatcgtccg tcgaccgcaa ccggggttgt tgctgactca gcgttcgatt
     2221 catctgcgta aacacgctgg acaagtggca ttccctggag gtgcagtcga tgacacggac
     2281 gcatcagcta tcgccgccgc gctgcgcgaa gctgaagaag aggtcgctat accgccttcc
     2341 gccgttgaag ttatcggcgt gctgccgccc gtcgatagcg tcactggcta ccaggtaacc
     2401 ccagtggtcg gcattatccc gcccgatctg ccgtatcgcg ccagtgaaga tgaagtctcg
     2461 gcggtgtttg aaatgccgct cgcccaggca ttacatctgg gtcgttatca ccctttagat
     2521 atctaccgcc gtggtgattc acatcgggta tggctgtcct ggtacgaaca gtattttgta
     2581 tggggaatga ccgcaggcat aattcgtgag ctggcgctgc aaattggtgt gaaaccctga
     2641 ctatacttat ctttacatct acaaaacact acttgagaca atcatcgcaa tattagttaa
     2701 atcgcggttt ttgattagtt taattcatgt gaatagttaa gccagtcgcc gcgttccctc
     2761 ttacactatg cgctgttatt agttcgttac tggaagtcca gtcaccttgt caggagtatt
     2821 atcgtgatta gtctattcga catgtttaag gtggggattg gtccctcatc ttcccatacc
     2881 gtagggccta tgaaggcagg taaacagttc gtcgatgatc tggtcgaaaa aggcttactg
     2941 gatagcgtta ctcgcgttgc cgtggacgtt tatggttcac tgtcgctgac gggtaaaggc
     3001 caccacaccg atatcgccat tattatgggt cttgcaggta acgaacctgc caccgtggat
     3061 atcgacagta ttcccggttt tattcgcgac gtagaagagc gcgaacgtct gctgctggca
     3121 cagggacggc atgaagtgga tttcccgcgc gacaacggga tgcgttttca taacggcaac
     3181 ctgccgctgc atgaaaacgg tatgcaaatc cacgcctata acggcgatga agtcgtctac
     3241 agcaaaactt attattccat cggcggcggt tttatcgtcg atgaagaaca ctttggtcag
     3301 gatgctgcca acgaagtaag cgtgccgtat ccgttcaaat ctgccaccga actgctcgcg
     3361 tactgtaatg aaaccggcta ttcgctgtct ggtctcgcta tgcagaacga actggcgctg
     3421 cacagcaaga aagagatcga cgagtatttc gcgcatgtct ggcaaaccat gcaggcatgt
     3481 atcgatcgcg ggatgaacac cgaaggtgta ctgccaggcc cgctgcgcgt gccacgtcgt
     3541 gcgtctgccc tgcgccggat gctggtttcc agcgataaac tgtctaacga tccgatgaat
     3601 gtcattgact gggtaaacat gtttgcgctg gcagttaacg aagaaaacgc cgccggtggt
     3661 cgtgtggtaa ctgcgccaac caacggtgcc tgcggtatcg ttccggcagt gctggcttac
     3721 tatgaccact ttattgaatc ggtcagcccg gacatctata cccgttactt tatggcagcg
     3781 ggcgcgattg gtgcattgta taaaatgaac gcctctattt ccggtgcgga agttggttgc
     3841 cagggcgaag tgggtgttgc ctgttcaatg gctgctgcgg gtcttgcaga actgctgggc
     3901 ggtagcccgg aacaggtttg cgtggcggcg gaaattggca tggaacacaa ccttggttta
     3961 acctgcgacc cggttgcagg gcaggttcag gtgccgtgca ttgagcgtaa tgccattgcc
     4021 tctgtgaagg cgattaacgc cgcgcggatg gctctgcgcc gcaccagtgc accgcgcgtc
     4081 tcgctggata aggtcatcga aacgatgtac gaaaccggta aggacatgaa cgccaaatac
     4141 cgcgaaacct cacgcggtgg tctggcaatc aaagtccagt gtgactaata cttcttactc
     4201 gcccatctgc aacggatggg cgaatttata cccgctttct cgtctgctgt aatattcccc
     4261 actacacttc cactgttgcg tcaggcgttt gtcgccatac gcttacaggg tggcccgcat
     4321 gcaaaaagca caacggatca ttaaaaccta tcgtcgtaat cgaatgattg tttgtacgat
     4381 ttgcgcactc gttacgctcg cttcgaccct gagcgtgcga tttatttcac agcgtaactt
     4441 aaatcaacaa cgggtagtac aattcgccaa tcacgctgta gaggaattag ataaagtact
     4501 gcttccccta caggcaggta gcgaagtctt gcttccgctg attggtctgc cctgctctgt
     4561 cgcccatttg ccattacgta aacaggcggc aaaactccaa actgtgcgat ccattggcct
     4621 ggtgcaagac ggcacacttt attgctccag catttttggt tatcgcaatg tgcccgtcgt
     4681 ggacattctg gctgaacttc ctgcaccgca accactttta cgcctgacga tcgaccgtgc
     4741 cctgattaaa ggcagtccgg ttttgattca atggacgcct gcagcgggca gtagcaatgc
     4801 tggggtcatg gagatgatta acatcgactt actgacggca atgctgcttg agccacaact
     4861 gccgcaaatc agtagcgcca gcctgacggt ggacaaacgg catttgctct atggtaatgg
     4921 gctggtagat tcccttccgc aacctgaaga caatgaaaac tatcaggttt cttcgcaacg
     4981 ctttcctttt accattaacg ttaatggtcc gggggctacg gcgctggcat ggcactatct
     5041 tccaacacaa ttaccgctgg cggtgctgct aagtttactg gtgggctaca tcgcctggct
     5101 ggcgaccgct taccgaatga gcttttcccg cgaaatcaat ctgggcctgg cgcaacatga
     5161 gttcgaattg ttctgtcagc ctttgcttaa tgcgcgcagc cagcaatgta ttggtgtaga
     5221 gattttgctg cgctggaaca atccgcgtca gggctggatt tcaccggatg tgtttattcc
     5281 tatcgcggaa gaacatcatt taattgtgcc actgacccgc tatgtgatgg cagaaaccat
     5341 tcgtcagcgc catgttttcc cgatgagtag tcagtttcat gttggcatta acgtcgcacc
     5401 cagccatttt cgccgtggtg tgctgataaa agatctcaat cagtactggt ttagcgctca
     5461 cccgattcag caactgatcc tcgaaatcac cgaacgcgat gccttactgg atgttgatta
     5521 tcggattgcc cgcgagctgc atcgtaaaaa cgtcaaactg gcgattgatg acttcggcac
     5581 cggcaacagc tcgttttcct ggcttgaaac attacgtcct gacgtgctga aaattgataa
     5641 gtcatttacc gcagctatag gttctgacgc ggttaactcg acggtgaccg atatcatcat
     5701 cgcgctgggg caaagactga atattgaact ggtggcggag ggcgtggaaa cgcaagaaca
     5761 ggcgaagtat ttgcgccgtc atggcgtgca tattttgcaa gggtatttgt acgcacagcc
     5821 gatgccgcta cgtgattttc ccaaatggct ggcgggcagc caaccgccgc ccggcataat
     5881 ggacatatca cgcccattat gccgttacgt taacgcttac tcatcttcat cgtgcgccgg
     5941 ttgctcttta acaatgcgaa ccagatcaac acgataatca ttggcttcaa tgatggtgat
     6001 atgcagtggc cctacatcaa tcacatcgcc cacacgggga atgtgaccat ttgccgagat
     6061 cacgaggccc gcgaccgtcg cgatatcatc gtcatcggca aggtgctcaa catcaagcgc
     6121 ctgctgcaag gcatgcaaat ctgtaccgcc ttttaccagc cagccgtcac catcagtaat
     6181 gatttccggc gtttcgtcag cgtccgggaa ttcacccgca atggcttcca gcacatccag
     6241 cggcgtgacc agaccttgta ccacaccaaa ctcgttggtc acgataacaa agctcccgcg
     6301 agcacgacgc agcacgccca acaggttgat cggatcgagg gtttccggga cgataatcgc
     6361 cggagacgcc gaagcaatcg ccgccacatc aacgccctct tccagcgcca ccagcagttc
     6421 tttagcacgt acaataccga tgatttcatc cagttcaccg cgacataccg ggaacagact
     6481 gtgcggtgaa gagagcagtt gctcgcggat ttcatcgacc ccgagattag cgtcaaccca
     6541 gcttatttca ccgcgcggcg tcatgatccc gcgcagagaa cgcgacgcca gcgtcagtac
     6601 gccgttaatc atgtaacgtt cttcttcggc aaatgcacct tccgggatcg gcatcggcat
     6661 cgggttatcg gcatcgtgct gaacattggc ctgacgtttc ccgcccatca aacgcaggat
     6721 ggcatcggca gtacgcgctc gcagcggcaa agtcgactgg tggcgaataa agttgcgacg
     6781 cgcaatctgg ttaaacactt cgatgatgat cgagaagcca atcgcggcat acaggtaacc
     6841 tttcggaatg tggaaaccga aaccttctgc caccagactc agaccaatca ttaacaggaa
     6901 gctcagacag agcaccacca ccgtggggtg ctggttaacg aatcgcgtca gcggtttgga
     6961 tgccagcaac ataaccgcca tcgcaatcac taccgccgcc atcatcaccg gcagatggtt
     7021 aaccatccct actgcagtaa ttaccgcatc caacgagaag acggcgtcaa ggatgacaat
     7081 ctgtgtgacg accacccaga aactggcgta gcctttaccg tggccggaat catgatcgcg
     7141 gttttccagc cgttcatgca gttcggttgt tgctttgaac agcaagaata tccccccgaa
     7201 caacataatc aggtcgcgtc cggagaagga gaaatccatg acggtaaata gcggtttggt
     7261 cagcgtgacc atccatgaaa tcagcgacag cagccccaga cgcataatca gcgccagtga
     7321 taaccccagc aaacgcgctt tatcgcgttg ttttggcggc agtttgtcag caagaatggc
     7381 gatgaagacc aggttatcga tacccagcac aatttcgaga acaacaagcg tgagtagccc
     7441 cgcccaaatt gaggggtcca ttaagaattc catgacaagc tcctgcttaa ggaatagcta
     7501 ttcgacgcca gaaataatgc aggcgtaacg acaaaatgca aacgaaaggt gcggcataga
     7561 gtgccagaaa ggcaggcgtt aaaaggcctg atgctgaaat gacgtcggtg acgatccata
     7621 ctgcgggcta ctgccctata ctccatggtt gttaaacggg agttaaacat atcagagacg
     7681 cctctgattt ggcaaagatt taccttcctt tgcaaacgaa tgtgacaagg atattttacc
     7741 tttcgaaatt tctgctaatc gaaagttaaa ttacggatct tcatcacata aaataatttt
     7801 ttcgatatct aaaataaatc gcgaaacgca ggggtttttg gttgtagccc ttatctgaat
     7861 cgattcgatt gtggacgacg attcaaaaat acatctggca cgttgaggtg ttaacgataa
     7921 taaaggaggt agcaagtgac cattgctatt gttataggca cacatggttg ggctgcagag
     7981 cagttgctta aaacggcaga aatgctgtta ggcgagcagg aaaacgtcgg ctggatcgat
     8041 ttcgttccag gtgaaaatgc cgaaacgctg attgaaaagt acaacgctca gttggcaaaa
     8101 ctcgacacca ctaaaggcgt gctgtttctc gttgatacat ggggaggcag cccgttcaat
     8161 gctgccagcc gcattgtcgt cgacaaagag cattatgaag tcattgcagg cgttaacatt
     8221 ccaatgctcg tggaaacgtt aatggcccgt gatgatgacc caagctttga tgaactggtg
     8281 gcactggcag tagaaacagg ccgtgaaggc gtgaaagcac tgaaagccaa accggttgaa
     8341 aaagccgcgc cagcacccgc tgccgcagca ccaaaagcgg ctccaactcc ggcaaaacca
     8401 atggggccaa acgactacat ggttattggc cttgcgcgta tcgacgaccg tctgattcac
     8461 ggtcaggtcg ccacccgctg gaccaaagaa accaatgtct cccgtattat tgttgttagt
     8521 gatgaagtgg ctgcggatac cgttcgtaag acactgctca cccaggttgc acctccgggc
     8581 gtaacagcac acgtagttga tgttgccaaa atgattcgcg tctacaacaa cccgaaatat
     8641 gctggcgaac gcgtaatgct gttatttacc aacccaacag atgtagagcg tctcgttgaa
     8701 ggcggcgtga aaatcacctc tgttaacgtc ggtggtatgg cattccgtca gggtaaaacc
     8761 caggtgaata acgcggtttc ggttgatgaa aaagatatcg aggcgttcaa gaaactgaat
     8821 gcgcgcggta ttgagctgga agtccgtaag gtttccaccg atccgaaact gaaaatgatg
     8881 gatctgatca gcaaaatcga taagtaacgt attgtgttga ttatcactca gttttcacac
     8941 ttaagtctta cgtaaacagg agaagtacaa tggagattac cactcttcaa attgtgctgg
     9001 tatttatcgt agcctgtatc gcaggtatgg gatcaatcct cgatgaattt cagtttcacc
     9061 gtccgctaat cgcgtgtacc ctggtgggta tcgttcttgg ggatatgaaa accggtatta
     9121 ttatcggtgg tacgctggaa atgatcgcgc tgggctggat gaacatcggt gctgcagttg
     9181 cgcctgacgc cgctctggct tctatcattt ctaccattct ggttatcgca ggtcatcaga
     9241 gcattggtgc aggtatcgca ctggcaatcc ctctggccgc tgcgggccag gtactgacca
     9301 tcatcgttcg tactattacc gttgctttcc agcacgctgc ggataaggct gctgataacg
     9361 gcaacctgac agcgatttcc tggatccacg tttcttctct gttcctgcaa gcaatgcgtg
     9421 tggctattcc ggccgtcatc gttgcgctgt ctgttggtac cagcgaagta cagaacatgc
     9481 tgaatgcgat tccggaagtg gtgaccaatg gtctgaatat cgccggtggc atgatcgtgg
     9541 tggttggtta tgcgatggtt atcaacatga tgcgtgctgg ctacctgatg ccgttcttct
     9601 acctcggctt cgtaaccgca gcattcacca actttaacct ggttgctctg ggtgtgattg
     9661 gtactgttat ggcagtgctc tacatccaac ttagcccgaa atacaaccgc gtagccggtg
     9721 cgcctgctca ggcagctggt aacaacgatc tcgataacga actggactaa caggtgagcg
     9781 aaatggttga tacaactcaa actaccaccg agaaaaaact cactcaaagt gatattcgtg
     9841 gcgtcttcct gcgttctaac ctcttccagg gttcatggaa cttcgaacgt atgcaggcac
     9901 tgggtttctg cttctctatg gtaccggcaa ttcgtcgcct ctaccctgag aacaacgaag
     9961 ctcgtaaaca agctattcgc cgtcacctgg agttctttaa cacccagccg ttcgtggctg
    10021 cgccgattct cggcgtaacc ctggcgctgg aagaacagcg tgctaatggc gcagagatcg
    10081 acgacggtgc tatcaacggt atcaaagtcg gtttgatggg gccactggct ggtgtaggcg
    10141 acccgatctt ctggggaacc gtacgtccgg tatttgcagc actgggtgcc ggtatcgcga
    10201 tgagcggcag cctgttaggt ccgctgctgt tcttcatcct gtttaacctg gtgcgtctgg
    10261 caacccgtta ctacggcgta gcgtatggtt actccaaagg tatcgatatc gttaaagata
    10321 tgggtggtgg cttcctgcaa aaactgacgg aaggggcgtc tatcctcggc ctgtttgtca
    10381 tgggggcatt ggttaacaag tggacacatg tcaacatccc gctggttgtc tctcgcatta
    10441 ctgaccagac gggcaaagaa cacgttacta ctgtccagac tattctggac cagttaatgc
    10501 caggcctggt accactgctg ctgacctttg cttgtatgtg gctactgcgc aaaaaagtta
    10561 acccgctgtg gatcatcgtt ggcttcttcg tcatcggtat cgctggttac gcttgcggcc
    10621 tgctgggact gtaagactgt tgtacactac cggggccttt tggccccgtt tttttatctg
    10681 gaggattaat gacaatcacg gacctggtac tgattctttt catcgccgca ctcctggcct
    10741 tcgcgatcta cgatcagttc atcatgcccc gccgtaacgg ccccaccctg ctggcaattc
    10801 ctttgctccg gcgtggtcgc atcgatagcg ttatcttcgt cggattgatt gtcattctta
    10861 tctataacaa cgtcacgaat catggtgcgt taataacgac atggttatta agcgcactgg
    10921 ctctgatggg tttttatata ttctggatcc gcgttccgaa gatcatcttt aaacaaaaag
    10981 gttttttctt cgccaatgtc tggattgaat atagccgaat caaagcgatg aacttgtcgg
    11041 aagatggcgt gttggtgatg caattagaac agcgtcggct gttaatccgc gttcgaaata
    11101 tcgacgatct ggaaaaaatt tataagcttc tcgtttcaac tcaataagtt atgaatttag
    11161 ccaaagctat gcttagtgta tttttaataa tcagacatag cttaggctat attacctctt
    11221 cccttatttg ttatttattt taacgtttca ttgatatata aatccaaat
//
LOCUS       DAPOAV010000120        10794 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.120, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000120 DAPOAV010000000
VERSION     DAPOAV010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10794
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.120"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            53..94
                     /locus_tag="RN951_003917"
     CDS             53..94
                     /locus_tag="RN951_003917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528844.1"
                     /translation="MVQLVDLARCVSF"
     gene            132..1514
                     /gene="dosC"
                     /locus_tag="RN951_003918"
     CDS             132..1514
                     /gene="dosC"
                     /locus_tag="RN951_003918"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DosC"
                     /protein_id="HDX2528845.1"
                     /translation="MEMYFKRMKDEWTGLVEQADPPIRAKAAEIAVAHAHYLSIEFYR
                     IVRIDPHAEEFLSNEQVERQLKSAMERWIINVLSAQVDDVERLIQIQHTVAEVHARIG
                     IPVEIVEMGFRVLKKILYPVIFSSDYSAAEKLQVYHFSINSIDIAMEVMTRAFTFSDS
                     SASKEDENYRIFSLLENAEEEKERQIASILSWEIDIIYKILLDSDLGSSLPLSQADFG
                     LWFNHKGRHYFSGIAEVGHISRLIQDFDGIFNQTMRNTRNLNNRSLRVKFLLQIRNTV
                     SQIITLLRELFEEVSRHEVGMDVLTKLLNRRFLPTIFKREIAHANRTGTPLSVLIIDV
                     DKFKEINDTWGHNTGDEILRKVSQAFYDNVRSSDYVFRYGGDEFIIVLTEASENETLR
                     TAERIRSRVEKTKLKAANGEDIALSLSIGAAMFNGHPDYERLIQIADEALYIAKRRGR
                     NRVELWKASL"
     gene            1539..3938
                     /gene="dosP"
                     /locus_tag="RN951_003919"
                     /gene_synonym="pdeO"
     CDS             1539..3938
                     /gene="dosP"
                     /locus_tag="RN951_003919"
                     /gene_synonym="pdeO"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416006.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-sensing cyclic-di-GMP phosphodiesterase"
                     /protein_id="HDX2528846.1"
                     /translation="MKLTDADNAADGIFFPALEQNMMGAVLINENDEVMFFNPAAEKL
                     WGYKREEVIGNNIDMLIPRDLRPAHPEYIRHNREGGKARVEGMSRELQLEKKDGSKIW
                     TRFALSKVSAEGKVYYLALVRDASVEMAQKEQTRQLIIAVDHLDRPVIVLDPERHIVQ
                     CNRAFTEMFGYCISEASGMQPDTLLNIPEFPADNRIRLQQLLWKTARDQDEFLLLTRT
                     GEKIWIKASISPVYDVLAHLQNLVMTFSDITEERQIRQLEGNILAAMCSSPPFHEMGE
                     IICRNIESVLNESHVSLFALRNGMPIHWASSSHGAEIQNAQSWSATIRQRDGAPAGIL
                     QIKTSSGAETSAFIERVADISQHMAALALEQEKSRQHIEQLIQFDPMTGLPNRNNLHN
                     YLDDLVDKAVSPVVYLIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLKPDQYLCRI
                     EGTQFVLVSLENDVSNITQIADELRNVVSKPIMIDDKPFPLTLSIGISYDLGKNRDYL
                     LSTAHNAMDYIRKNGGNGWQFFSPAMNEMVKERLVLGAALKEAISNNQLKLVYQPQIF
                     AETGELYGIEALARWHDPLHGHVPPSRFIPLAEEIGEIENIGRWVIAEACRQLAEWRS
                     QNIHIPALSVNLSALHFRSNQLSNQVSDAMHAWGIDGHQLTVEITESMMMEHDTEIFK
                     RIQILRDMGVGLSVDDFGTGFSGLSRLVSLPVTEIKIDKSFVDRCLTEKRILALLEAI
                     TSIGQSLNLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRPLPAEEIPGWMSSVLPLK
                     I"
     gene            4196..4777
                     /gene="ddpX"
                     /locus_tag="RN951_003920"
     CDS             4196..4777
                     /gene="ddpX"
                     /locus_tag="RN951_003920"
                     /EC_number="3.4.13.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine dipeptidase"
                     /protein_id="HDX2528847.1"
                     /translation="MSDTTELVDLAVIFPDLEIELKYACADNITGKAIYQQARCLLHK
                     DAITALAKSISIAQLSGLQLVIYDAYRPQQAQAMLWQACPDPQYVVDVTVGSNHSRGT
                     AIDLTLRDEHGNILDMGAGFDEMHERSHAYHPSVPPAAQRNRLLLNAIMTGGGFVGIS
                     SEWWHFELPQAASYPLLADQFSCFISPGTQHVS"
     gene            4791..6341
                     /locus_tag="RN951_003921"
     CDS             4791..6341
                     /locus_tag="RN951_003921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDX2528848.1"
                     /translation="MKRSISFRPTLLALVLATNFPVAHAAVPKDMLVIGKAADPQTLD
                     PAVTIDNNDWTVTYPSYQRLVQYKTDGDKGSTDVEGDLASSWKASDDQKEWTFTLKDN
                     AKFADGTPVTAEAVKLSFERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFL
                     YTLANDGASIINPAVLKEHAADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYP
                     GNKPNFKRVSVKIIGESASRRLQLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLR
                     VTYLYLNNSKAPLNQADLRRAISWSTDYQGMVNGILSGNGKQMRGPIPEGMWGYDATA
                     MQYNHDETKAKAEWDKVTSKPTSLTFLYSDNDPNWEPIALATQSSLNKLGIIVKLEKL
                     ANATMRDRVGKGDYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYENSEVDKL
                     LRNALATTDQTQRTRDYQQAQKIVIDDAAYVYLFQKNYQLAMNKEVKGFVFNPMLEQV
                     FNINTMSK"
     gene            6343..7365
                     /locus_tag="RN951_003922"
     CDS             6343..7365
                     /locus_tag="RN951_003922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX2528849.1"
                     /translation="MTFWSILRQRCWGLVLVVAGVCVITFIISHLIPGDPARLLAGDR
                     ASDAIVENIRQQLGLDQPLYVQFYRYVSDLFHGDLGTSIRTGRPVLEELRIFFPATLE
                     LAFGALLLALLIGIPLGILSAVWRNRWLDHLVRIMAITGISTPAFWLGLGVIVLFYGH
                     LQILPGGGRLDDWLDPPTHVTGFYLLDALLEGNGEVFFNALQHLILPALTLAFVHLGI
                     VARQIRSAMLEQLSEDYIRTARASGLPGWYIVLCYALPNALIPSITVLGLALGDLLYG
                     AVLTETVFAWPGMGAWVVTSIQALDFPAVMGFAVVVSFAYVLVNLVVDLLYLWIDPRI
                     GRGGGE"
     gene            7362..8258
                     /locus_tag="RN951_003923"
     CDS             7362..8258
                     /locus_tag="RN951_003923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D,D-dipeptide ABC transporter permease"
                     /protein_id="HDX2528850.1"
                     /translation="MMLSEETSAVRPQKQTRFNGAKLVWMLKGSPLTVTSAVIIVLML
                     LMMIFSPWLATHDPNAIDLTARLLPPSAAHWFGTDEVGRDLFSRVLVGSQQSILAGLV
                     VVAIAGMIGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMALAAALGPSLFNAM
                     LAIAIVRIPFYVRLARGQALVVRQYTYVQAAKTFGASRWHLINWHILRNSLPPLIVQA
                     SLDIGSAILMAATLGFIGLGAQQPSAEWGAMVANGRNYVLDQWWYCAFPGAAILLTAV
                     GFNLFGDGIRDLLDPKAGGKQS"
     gene            8255..9241
                     /locus_tag="RN951_003924"
     CDS             8255..9241
                     /locus_tag="RN951_003924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX2528851.1"
                     /translation="MTQPVLDIQQLHLSFPGFNGDVHALNNVSLQINRGEIVGLVGES
                     GSGKSVTAMLIMRLLPTGSYCVHRGQISLLGEDVLNAREKQLRQWRGARVAMIFQEPM
                     TALNPTRRIGLQMMDVIRHHQPISRREARAKAIDLLEEMQIPDAVEVMSRYPFELSGG
                     MRQRVMIALAFSCEPQLIIADEPTTALDVTVQLQVLRLLKHKARASGTAVLFISHDMA
                     VVSQLCDSVYVMYAGSVIESGVTADVIHHPRHPYTIGLLQCAPEHGVPRQLLPAIPGT
                     VPNLTHLPDGCAFRDRCYAAGAQCENVPALTACGDNNQRCACWYPQQEVISV"
     gene            9234..10160
                     /locus_tag="RN951_003925"
     CDS             9234..10160
                     /locus_tag="RN951_003925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX2528852.1"
                     /translation="MSDTLLTLRDVHINFPARKNWLGKTTEHVHAINGIDLQIRRGET
                     LGIVGESGCGKSSLAQLLMGMLQPSHGQYIRSGSQRIMQMVFQDPLSSLNPRLPVWRI
                     ITEPLWIAKRSSEQQRRALAEELAVQVGIRPEYLDRLPHAFSGGQRQRIAIARALSSQ
                     PDVIVLDEPTSALDISVQAQILNLLVTLQENHGLTYVLISHNVSVIRHMSDRVAVMYL
                     GQIVELGDAQQVLTAPAHPYTRLLLDSLPAIDKPLEEEWALRKTDLPGNRTLPQGCFF
                     YERCPLATHGCEVRQSLAIREDGRELRCWRAL"
     gene            complement(10233..10664)
                     /gene="osmC"
                     /locus_tag="RN951_003926"
     CDS             complement(10233..10664)
                     /gene="osmC"
                     /locus_tag="RN951_003926"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin OsmC"
                     /protein_id="HDX2528853.1"
                     /translation="MTIHKKGQAHWEGDIKRGKGTVSTESGVLNQQPYGFNTRFEGEK
                     GTNPEELIGAAHAACFSMALSLMLGEAGFTPTSIDTTADVSLDKVDAGFAITKIALKS
                     EVAVPGIDASTFDGIIQKAKAGCPVSQVLKAEITLDYQLKS"
BASE COUNT         2628 a         2681 c         2783 g         2702 t
ORIGIN      
        1 ctgtcctaaa tcgcttattt cttttcagta tatcttcata tttcaggaga atatggtgca
       61 gttagtcgat ctcgcacgtt gcgtttcatt ttgattccgt ctgatttccc agccttataa
      121 gggtgtgaat tatggagatg tattttaaaa gaatgaaaga tgagtggacc ggacttgtcg
      181 aacaggcaga tccgcccatt cgtgctaaag ccgcggaaat tgccgttgcg catgctcatt
      241 atctgagtat cgagttttat cgaattgtcc gcatcgaccc gcatgccgaa gaattcttga
      301 gtaatgaaca agttgagcgg cagttgaaga gtgcgatgga acgctggatt attaacgtgc
      361 tttctgccca ggttgacgat gtcgaaaggc taatacaaat ccagcatacc gtcgcggaag
      421 tgcatgcccg cataggaatt ccggtagaaa ttgtcgagat ggggtttcgg gtgctgaaaa
      481 aaatcctcta tccggtgatc ttctcttcgg attattccgc cgcagaaaaa cttcaggtct
      541 accatttctc gattaacagt attgatatcg cgatggaagt gatgactcgc gcgtttacct
      601 ttagtgacag tagtgcctca aaggaagatg aaaactatcg tatcttctcg ttactggaaa
      661 acgccgaaga agaaaaagaa cggcaaatag cctcaatact ttcatgggaa atagatatta
      721 tctataaaat cctgctggat tctgatttag gcagtagttt gcctttaagc caggctgatt
      781 ttggcctgtg gtttaaccat aaaggtcgac attattttag tggtattgcc gaagtaggcc
      841 atatctcccg tctgattcag gatttcgacg gtattttcaa tcaaaccatg cgtaacacca
      901 gaaatttgaa taacagaagt ctgcgggtga aatttttatt acagataaga aataccgtat
      961 cgcaaattat taccttgctg cgtgaattgt ttgaagaagt atcgcgccac gaagtcggta
     1021 tggatgtact gacgaaatta cttaaccgcc gtttcctacc gactatcttc aaacgcgaaa
     1081 ttgcccatgc caaccggacc ggtacaccgc tgtcagtgct gattattgac gttgataaat
     1141 tcaaagagat caacgatacg tggggccata acactggtga tgaaattctg cgtaaagtct
     1201 ctcaggcctt ttatgacaac gtccgcagta gtgattatgt tttccgctac gggggcgatg
     1261 aatttatcat tgttttgact gaagcttctg aaaacgaaac gttacgtacc gcagaacgta
     1321 ttcgcagtcg ggtggagaaa accaaactga aagccgcaaa cggcgaagat attgccctct
     1381 cactttccat cggtgccgcc atgtttaatg gtcatcctga ctatgagcgc ctcattcaaa
     1441 tagccgatga agctctgtat atcgccaaaa gacgaggtag aaaccgtgtt gaactctgga
     1501 aagccagtct ttagatgcgc caggatgcag aggtaatcat gaagctaacc gatgcggata
     1561 atgccgccga tggcattttt ttccccgccc ttgagcaaaa tatgatgggt gcggtgttaa
     1621 ttaacgaaaa tgatgaagtg atgtttttca accccgccgc agagaagctc tggggataca
     1681 aacgtgaaga agtcattggc aataacattg atatgctgat tccgcgggat ttgcgtcctg
     1741 cgcatcctga atacattcgt cacaaccgtg aaggcggtaa agcgcgtgtt gaggggatga
     1801 gtcgggagct gcagctggag aaaaaagacg gcagtaaaat ctggacccgt tttgcgctat
     1861 cgaaagtgag cgccgagggg aaagtttatt acctggcgct ggtacgggat gccagcgtag
     1921 aaatggcgca aaaagaacag acccgacaat tgattattgc cgttgaccat ctcgaccgac
     1981 cggtgattgt cctcgatccg gaacgccata ttgtgcagtg caatcgcgca tttaccgaaa
     2041 tgtttggtta ctgcattagc gaagccagcg gtatgcagcc cgatacactc ctgaacattc
     2101 ctgaattccc tgccgataac cgcattcgtt tacaacagtt gctatggaaa accgcccgcg
     2161 atcaggacga atttctgctg ttgacgcgca ccggtgaaaa aatctggatt aaagcctcta
     2221 tcagcccggt ttatgacgtg ctcgcgcatc tgcagaacct ggtaatgact ttctcggata
     2281 tcaccgaaga acggcagatt cgccagcttg aaggcaatat tctcgccgcc atgtgcagca
     2341 gcccgccatt tcatgaaatg ggggaaatca tttgtcgtaa catcgaatct gtactcaacg
     2401 aatcgcatgt ttcgctgttc gcactgcgca acgggatgcc gatacactgg gcgtcatctt
     2461 cccacggtgc agaaattcaa aatgcgcaaa gctggtcagc gaccattcgt cagcgtgatg
     2521 gcgcgcctgc ggggatcctg caaattaaaa cctcgtcagg agcagaaacc agcgccttta
     2581 tcgaacgcgt ggcagatatc agccagcata tggccgcgct ggcgctggaa caggaaaaaa
     2641 gccgtcagca tattgaacaa ctcatccaat ttgatccgat gaccggtctg ccaaatcgca
     2701 ataacctgca caattacctc gatgacctgg tcgacaaagc cgtctctccc gtggtgtatc
     2761 tcatcggtgt tgaccatatt caggatgtga ttgatagcct tggctatgcg tgggccgatc
     2821 aggcattgct ggaagtggtc aatcgctttc gtgaaaaact caaaccggat cagtatctct
     2881 gtcgtatcga aggtacgcag tttgtcctcg tgagcctcga aaacgacgtc agtaacatta
     2941 cccaaatcgc cgatgagcta cggaatgtgg tcagcaagcc gataatgatt gacgataaac
     3001 ccttcccgct taccttgagt attggcatca gctacgacct gggtaaaaac cgcgattact
     3061 tgctctccac tgctcacaat gcaatggatt atattcgcaa gaatggcggt aacggctggc
     3121 agttcttcag cccggcgatg aacgaaatgg taaaagagcg tttggtttta ggcgcagcgc
     3181 tgaaagaagc gattagcaat aaccaactga aactggttta ccagccgcaa atcttcgcag
     3241 aaacgggtga actgtacggc atcgaagccc ttgctcgctg gcacgatccc ctgcatggtc
     3301 atgtgccccc ttcacggttt attcctctcg cagaagagat tggtgaaatc gaaaatattg
     3361 ggcgctgggt catcgcggaa gcttgccgtc agttagcaga atggcgtagc cagaatattc
     3421 atatcccggc gttatccgtg aacttgtcgg cgctgcactt tcgcagtaat caactgtcta
     3481 atcaggtgtc tgatgcaatg cacgcctggg gtattgacgg ccaccagctg acggtagaaa
     3541 tcacggaaag catgatgatg gaacacgata ccgaaatctt taagcgcatt cagatcctgc
     3601 gtgatatggg cgtgggctta tcggtagatg attttggtac gggcttttcc ggattatccc
     3661 gcttagtcag tcttccggta acggaaatca aaattgacaa aagttttgtc gatcgttgtc
     3721 tgaccgaaaa acgcatcctt gccttacttg aagccattac cagcattggg caaagcctca
     3781 atttaaccgt cgtggcggaa ggcgtcgaaa ccaaagagca atttgagatg ctacgcaaga
     3841 tccactgtcg cgttattcag ggatatttct tttcccgccc cctacccgcc gaagaaattc
     3901 caggctggat gagcagcgtg ttaccgctga aaatctgaca aattcctctc gcccgcactc
     3961 gcgggttttc atttaacgtg acactgtcac ttaaatactg tgatttcagc tacgattccg
     4021 ggagattcct tccttaactt cccctcttgc accaaaactg cactacgctg cacaaatgtt
     4081 gatcaaaagt taaaaaatat aactttaagc cagcattctg gcgcttatcc cggcatggca
     4141 tgagatctgc ataagcggaa agcgcagcaa tttttgtctt atacaggaac cgtttatgtc
     4201 ggataccacc gaactggttg atttagccgt aatcttccct gatctggaga tcgaattgaa
     4261 atacgcctgc gctgataaca tcacaggtaa agctatttat cagcaagcgc gttgtctgtt
     4321 acacaaggat gcgattaccg cgctggcgaa aagtatcagc atcgcccagc tgtcagggtt
     4381 acaactggtg atttacgatg cgtatcgccc acaacaagca caggcgatgt tgtggcaagc
     4441 ctgcccagac ccgcaatatg ttgttgatgt gacggtcggt tctaatcaca gccgtggcac
     4501 ggcgatcgac ctgacgcttc gtgatgagca cgggaacatc ctcgatatgg gcgcagggtt
     4561 cgatgaaatg cacgagcgct cccatgccta tcacccttcc gtcccgcccg ccgctcagcg
     4621 caatcggctg ttgctgaatg cgataatgac tggtggcggt tttgtcggta tctccagcga
     4681 atggtggcac ttcgaattac cccaggcagc gagttaccct ctgctcgctg atcaattctc
     4741 ttgttttata tcccctggca cacagcacgt cagttaatca ggaaactgtc atgaagagat
     4801 cgatatcgtt tcgtcccaca ttgctcgcgc tcgtccttgc cacaaatttc ccggttgcgc
     4861 acgccgccgt accaaaagat atgctggtga ttggtaaggc cgccgatcca caaaccctcg
     4921 acccggcggt aacaatagat aataacgact ggacagtgac ctacccgtct tatcagcggc
     4981 tggttcagta caaaacggac ggtgataaag gctcaaccga cgttgaaggc gatctggcaa
     5041 gtagctggaa agcgtctgac gatcaaaaag agtggacgtt caccctgaaa gataatgcta
     5101 aatttgccga tggcacacct gtcactgccg aagcagtaaa actttctttt gagcggctac
     5161 taaaaatcgg ccaggggcca gcagaagcat ttcccaaaga tttaaagatt gatgctcccg
     5221 acgaacatac ggtgaagttt acccttagcc aaccattcgc accgttcctc tacacgctgg
     5281 cgaatgacgg tgcatccatt atcaatccgg cggtcttaaa ggaacatgca gcggatgatg
     5341 ctcgcggctt cctcgcgcaa aataccgccg gttccggacc atttatgctg aaaagctggc
     5401 aaaaaggtca gcaattagtt ctggtgccaa atccgcatta cccaggcaat aaaccgaact
     5461 tcaaacgggt atcggtaaaa attattggtg aaagtgcctc ccgtcgcctg cagctctccc
     5521 gtggcgacat tgacattgcc gatgcgctgc cggtggatca actcaacgcc ctgaagcagg
     5581 aaaataaagt caatgtggca gagtatccgt cactgcgcgt tacctatctg tatctgaata
     5641 acagcaaagc gcctcttaat caggcggatc tgcgtcgggc catttcctgg tctaccgatt
     5701 atcagggcat ggttaacggc attctgagtg gtaacggaaa acagatgcgc ggcccgattc
     5761 cggaaggcat gtggggctac gatgcgacgg caatgcaata caaccatgac gaaacgaaag
     5821 ccaaagccga atgggataaa gtgacgagca aacccaccag cctgacgttt ctctactccg
     5881 ataacgatcc gaactgggag cctattgctc tggcgacaca atccagtctc aacaagctgg
     5941 gcatcattgt gaagctggaa aagctggcga acgccaccat gcgcgacaga gtgggtaaag
     6001 gtgattacga cattgcgatt ggcaactgga gtccggattt tgccgacccg tatatgttta
     6061 tgaattactg gtttgagtca gacaaaaaag gtctgccggg taaccgctcg ttctatgaaa
     6121 acagtgaggt cgataagtta ctgcgcaatg cgcttgcgac caccgaccag acgcagcgta
     6181 cccgggacta ccagcaggca cagaaaatcg tcattgatga cgctgcttat gtgtacctgt
     6241 tccagaaaaa ctaccaactg gcgatgaaca aagaggtgaa aggctttgtg ttcaatccca
     6301 tgctggaaca ggtcttcaat atcaatacca tgagtaaata acgtgacctt ctggagtatt
     6361 ttacgccaac gctgctgggg gctggtgctc gtggtggcgg gcgtctgcgt gattacgttt
     6421 attatctcgc atctgatccc tggtgatccg gcgcggttac tggcgggtga ccgcgccagc
     6481 gatgctatcg tggaaaatat tcgccagcaa ctgggactgg accagccact gtatgtacag
     6541 ttttaccgct acgtcagcga cctgtttcat ggtgacctgg gaacatccat tcgtaccggg
     6601 cgtccggtgc tggaagagtt gcgtatattt ttcccggcga cgctggagct ggcttttggt
     6661 gccctgctgc tggcactcct gattggcatc ccgctgggca tactctctgc agtctggcga
     6721 aatcgctggc tggatcatct ggtgcgaata atggccatta ccggaatctc cacacctgcg
     6781 ttctggcttg ggctgggcgt cattgtgctg ttttatggtc atctgcaaat tcttcccggc
     6841 ggcggaaggc ttgatgactg gctggatcca ccaacgcacg ttaccggctt ttatctgctc
     6901 gatgcgctgc ttgaaggcaa cggtgaagtc ttcttcaatg cgttgcaaca tctcatctta
     6961 ccagcattaa cgctggcgtt cgttcacctg ggaattgtcg ctcgccagat ccgctcagcg
     7021 atgctggaac aattgagtga agactacatt cgtaccgccc gggccagcgg cttgcccggc
     7081 tggtatatcg ttttatgtta tgcgctaccc aatgcgttga tcccatcgat taccgtattg
     7141 ggtttggcgc tgggcgattt gttgtatggc gcagtgctca ccgaaaccgt ttttgcctgg
     7201 cccggaatgg gtgcatgggt agtaacatca atacaggcgc tcgacttccc ggcagtgatg
     7261 ggctttgccg tcgtggtttc atttgcttat gtgctggtca acctggtggt ggatttgctc
     7321 tatttgtgga ttgatccgcg tatcggacgt ggaggtggtg aatgatgcta agcgaggaaa
     7381 cgtccgccgt acgcccacaa aaacaaacgc gatttaacgg tgcaaaactg gtatggatgc
     7441 tgaaaggcag tccgctcacc gtgaccagcg cagtcatcat tgtattaatg ctattgatga
     7501 tgattttttc accgtggctg gcgacgcatg atcccaacgc cattgattta accgcccgcc
     7561 ttttgccgcc ttctgcggcg cactggtttg gcaccgatga agtgggacgc gatctgttta
     7621 gccgcgtact ggtcggcagt cagcaatcaa ttctcgccgg attagtcgtg gttgccattg
     7681 cgggtatgat tggttcgcta ctcggatgtc tatccggtgt gcttggtgga cgcgcagacg
     7741 ccatcatcat gcgcatcatg gacattatgc tgtcgattcc ttcgttggta ctgacaatgg
     7801 cactggctgc cgctctcggg ccgagtttgt ttaacgccat gctggctatt gctattgtgc
     7861 gaattccctt ttatgtgcgc ctggcgcggg ggcaagcatt agttgtacgc cagtatacct
     7921 atgttcaggc ggcgaaaacc tttggcgcgt ctcgttggca tctgatcaac tggcatattt
     7981 tacgtaactc cctaccgccg ctgatcgtgc aggcatcgct ggatatcggt agcgcgattt
     8041 taatggccgc cacgttggga tttattggcc tgggtgctca acaaccgagt gctgaatggg
     8101 gcgcgatggt agcaaatggt cgcaactatg tactcgatca gtggtggtat tgcgcatttc
     8161 cgggggcagc gattttgctt accgccgtcg ggtttaatct ctttggtgat ggtattcgcg
     8221 atctgcttga cccgaaagca ggaggaaagc agtcatgacc caacccgttc tggacattca
     8281 acaactgcat ttgagtttcc ccggttttaa cggtgatgtt cacgcgctca acaatgtgtc
     8341 cttgcagatt aaccgcggtg aaattgtcgg tctggtggga gaatccggct caggtaaatc
     8401 agtcaccgca atgctgatta tgcgtctgct accgacgggc agttattgcg tacatcgggg
     8461 gcagatttcc ctgctgggag aagatgttct taacgcgcgg gaaaaacagc ttcgtcagtg
     8521 gcgcggcgca cgagtggcga tgatctttca ggaaccgatg accgccctca atccgacacg
     8581 tcgaataggt cttcagatga tggacgtgat ccgccatcat caaccaataa gtcgtcggga
     8641 agccagagct aaagcgattg acttgctgga agagatgcaa atcccggatg ccgtggaagt
     8701 tatgtcgcgc tatccgtttg agctttcagg tggtatgcgc cagcgggtaa tgattgcgct
     8761 ggcattctcc tgcgagccgc aattgattat tgccgacgaa ccgactacgg cgctggacgt
     8821 cacggtgcag ttgcaggtac tgcgtttgct taaacataaa gcccgcgcca gtggaactgc
     8881 ggttctgttc atcagccatg atatggccgt ggtgtcgcaa ctgtgcgata gcgtttacgt
     8941 gatgtatgcc ggaagcgtaa ttgaaagcgg cgtgacggca gacgttatcc atcatccccg
     9001 gcatccgtat accattggtt tgctgcaatg cgcaccagaa catggagtac cacgccagct
     9061 attacccgcc attccaggga cggtaccaaa cctcacccat ttgcctgacg gctgcgcttt
     9121 tcgcgatcgt tgctatgcgg caggtgcaca gtgtgaaaac gtcccggcgc tgacagcgtg
     9181 tggtgacaac aaccagcgct gtgcctgttg gtatccgcag caggaggtta taagtgtctg
     9241 acacgttatt aacgttacgc gacgtccata tcaatttccc ggcccgtaaa aactggcttg
     9301 gtaaaactac ggaacatgtt catgccatta atggtattga tttacagatc cgccgtggtg
     9361 aaaccttagg gatcgtcggc gagtcaggct gcggcaaaag cagcctcgca cagcttttaa
     9421 tgggtatgct gcaaccgagc cacgggcagt acatccgttc tggctcacaa cgcattatgc
     9481 agatggtgtt tcaggacccg ctctcttcgc ttaatccgcg cttaccggtg tggcgcatca
     9541 tcacagaacc gctctggata gctaagcgta gtagtgaaca acagcggcga gcgttggcag
     9601 aggagttggc tgtgcaggtg ggtattcgtc cggagtatct cgaccgcctg cctcatgcgt
     9661 tctccggcgg gcagcggcaa cgtatcgcca ttgccagagc actctcttcg cagcctgacg
     9721 tgattgtgct tgatgagcca acctctgcgc tggatatctc cgttcaggcg cagatcctca
     9781 atttactggt aacgctacag gaaaatcacg ggctgaccta tgtgctgatt tcacacaatg
     9841 tctcggtgat acgtcatatg agcgatcggg tggcggtgat gtatctcggg cagattgtag
     9901 aactgggcga cgcgcagcag gtgctgacgg cacctgcaca tccatacacc cgattattgc
     9961 tggattccct ccccgccatt gataaaccgc tggaggaaga atgggcatta cgtaaaacgg
    10021 atctgccggg aaaccgcacg ttgccgcaag gctgtttttt ctacgaacgt tgcccgctgg
    10081 caacccacgg atgtgaagtc cggcaatcat tagcaataag ggaggacgga cgtgagctcc
    10141 ggtgctggcg ggcgctgtag agatgctaac gctgtagaga tgctaacaac gcatcaggca
    10201 ttcacgcgcc tgacgcgtca tccggcaatg ctttacgatt tcaactggta atccagcgta
    10261 atttccgctt tcagtacctg agagaccggg catcctgctt ttgctttctg gattatgccg
    10321 tcaaaggtag aggcatcaat acccggcacc gcaacttcac tcttcagtgc gattttcgta
    10381 atcgcaaaac cggcatccac tttatccagc gacacatcgg cggtggtatc aatcgatgtt
    10441 ggcgtgaatc ccgcttcccc cagcattaat gaaagcgcca ttgagaaaca tgcggcatgc
    10501 gctgcgccaa tcagttcttc agggttggtt cctttttcgc cttcaaaacg cgtgttaaat
    10561 ccatacggct gttggttcag cacgccactc tcggtggata ctgttccctt cccgcgtttg
    10621 atatcacctt cccagtgtgc ctgacctttc ttatggattg tcattgttgc tctcctgtgg
    10681 gcttaaaaag gaaattatag actacgtgag aaacagcacg aggataagca ggatattccg
    10741 aataaaatcc ggcgaaaata ttacttctgc acttaaatta aattcccaca atag
//
LOCUS       DAPOAV010000121        10540 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.121, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000121 DAPOAV010000000
VERSION     DAPOAV010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10540
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.121"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..883)
                     /locus_tag="RN951_003927"
     CDS             complement(<1..883)
                     /locus_tag="RN951_003927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416294.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-hexose-6-phosphate mutarotase"
                     /protein_id="HDX2528854.1"
                     /translation="MIKKIFALPVIEQISPVLSRRKLDELDLIVVDHPQVKASFALQG
                     AHLLSWKPAGEEEVLWLSNNTPFKNGVAIRGGVPVCWPWFGPAAQQGLPAHGFARNLP
                     WTLKSHHEDADGVALTFELTQSEETKKFWPHDFTLLAHFRVGKTCEIDLESHGEFETT
                     SALHTYFNVGDIAKVSVSGLGDRFIDKVNDAKENVLTDGIQTFPDRTDRVYLNPQDCS
                     VINDEALNRIIAVGHQHHLNVVGWNPGPALSISMGDMPDDGYKTFVCVETAYASETQK
                     VTKEKPAHLAQSIRVAKR"
     gene            complement(967..1962)
                     /gene="gapA"
                     /locus_tag="RN951_003928"
     CDS             complement(967..1962)
                     /gene="gapA"
                     /locus_tag="RN951_003928"
                     /EC_number="1.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006322611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDX2528855.1"
                     /translation="MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYM
                     LKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLT
                     DETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAK
                     VINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKV
                     LPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTE
                     DDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK"
     gene            2304..2717
                     /gene="msrB"
                     /locus_tag="RN951_003929"
     CDS             2304..2717
                     /gene="msrB"
                     /locus_tag="RN951_003929"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HDX2528856.1"
                     /translation="MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVY
                     HCLICDAPLFHSQTKYDSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHL
                     GHVFPDGPQPTGERYCVNSASLRFTDGENGEEING"
     gene            2759..3031
                     /locus_tag="RN951_003930"
     CDS             2759..3031
                     /locus_tag="RN951_003930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416291.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaC family protein"
                     /protein_id="HDX2528857.1"
                     /translation="MNLDDIINSMMPEVYQRLSTAVELGKWPDGVALTEEQKENCLQL
                     VMLWQARHNIEAQHMTIDTNGQMVMKSKQQLKEDFGISAKPIAMFK"
     gene            3401..4477
                     /locus_tag="RN951_003931"
     CDS             3401..4477
                     /locus_tag="RN951_003931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HDX2528858.1"
                     /translation="MKALARFGKAFGGYKMIDVPQPMCGPEDVVIEIKAAAICGADMK
                     HYNVDSGSDEFNSIRGHEFAGCIAQVGEKVKDWKVGQRVVSDNSGHVCGVCPACEQGD
                     FLCCTEKVNLGLDNNTWGGGFSKYCLVPGEILKIHRHALWEIPDGVDYEDAAVLDPIC
                     NAYKSIAQQSKFLPGQDVVVIGTGPLGLFSVQMARIMGAVNIVVVGLQEDVAVRFPVA
                     KELGATAVVNGSTEDVVARCQQICGKDNLGLVIECSGANIALKQAIEMLRPNGEVVRV
                     GMGFKPLDFSINDITAWNKSIIGHMAYDSTSWRNAIRLLASGAIKVKPMITHRIGLSQ
                     WREGFDAMVDKTAIKVIMTYDFDE"
     gene            4504..5883
                     /locus_tag="RN951_003932"
     CDS             4504..5883
                     /locus_tag="RN951_003932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2528859.1"
                     /translation="MEQITKPHCGARLDRLPDCRWHSSMFAIVAFGLLVCWSNAVGGL
                     ILAQLKALGWTDNSTTATFSAITTAGMFLGALVGGIIGDKTGRRNAFILYEAIHIASM
                     VVGAFSPNMDFLIACRFVMGVGLGALLVTLFAGFTEYMPGRNRGTWSSRVSFIGNWSY
                     PLCSLIAMGLTPLISAEWNWRVQLLIPAILSLIATALAWRYFPESPRWLESRGRYQEA
                     EKVMRSIEEGVIRQTGKPLPPVVIADDGKAPQAVPYSALLTGVLLKRVILGSCVLIAM
                     NVVQYTLINWLPTIFMTQGINLKDSIVLNTMSMFGAPFGIFIAMLVMDKIPRKTMGVG
                     LLILIAVLGYIYSLQTSMLLITLIGFFLITFVYMYVCYASAVYVPEIWPTEAKLRGSG
                     LANAVGRISGIAAPYAVAVLLSSYGVTGVFILLGAVSIIVAIAIATIGIETKGVSVES
                     LSIDAVANK"
     gene            5900..6943
                     /locus_tag="RN951_003933"
     CDS             5900..6943
                     /locus_tag="RN951_003933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="HDX2528860.1"
                     /translation="MKNSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVH
                     GFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCL
                     EGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHA
                     AMLADVKPGKKIIILGAGCIGLMTLQACKCLGATEIAVVDVLEKRLAMAEQLGATVVI
                     NGAKEDTIARCQQFTEDMGADIVFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGDSAI
                     NFLKINREVTIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFEESVNN
                     KRDIIKGVIKISD"
     gene            6964..7800
                     /locus_tag="RN951_003934"
     CDS             6964..7800
                     /locus_tag="RN951_003934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HDX2528861.1"
                     /translation="MLADIRYWENDATNKHYAIAHFNVWNAEMLMGVIDAAEEAKSPV
                     IISFGTGFVGNTSFEDFSHMMVSMAQKATVPVITHWDHGRSMEIIHNAWTHGMNSLMR
                     DASAFDFEENIRLTKEAVDFFHPLGIPVEAELGHVGNETVYEEALAGYHYTDPDQAAE
                     FVERTGCDSLAVAIGNQHGVYTSEPQLNFEVVKRVRDAVSVPLVLHGASGISDADIKT
                     AISLGIAKINIHTELCQAAMVAVKENQDQPFLHLEREVRKAVKERALEKIKLFGSDGK
                     AE"
     gene            7805..8752
                     /locus_tag="RN951_003935"
     CDS             7805..8752
                     /locus_tag="RN951_003935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416286.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase family protein"
                     /protein_id="HDX2528862.1"
                     /translation="MDNLDVICIGAAIVDIPLQPVSKNIFDVDSYPLERIAMTTGGDA
                     INEATIISRLGHRTALMSRIGKDAAGQFILDHCRKENIDIQSLKQDVSIDTSINVGLV
                     TEDGERTFVTNRNGSLWKLNIDDVDFARFSQAKLLSLASIFNSPLLDGKALTEIFTQA
                     KARQMIICADMIKPRLNETLDDICEALSYVDYLFPNFAEAKLLTGKETLDEIADCFLA
                     CGVKTVVIKTGKDGCFIKRGDMTMKVPAVAGITAIDTIGAGDNFASGFIAALLEGKNL
                     RECARFANATAAISVLSVGATTGVKNRKLVEQLLEEYEG"
     gene            8762..9742
                     /gene="ydjG"
                     /locus_tag="RN951_003936"
     CDS             8762..9742
                     /gene="ydjG"
                     /locus_tag="RN951_003936"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent methylglyoxal reductase"
                     /protein_id="HDX2528863.1"
                     /translation="MKKIPLGTTDITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILE
                     AHRCGINLIDTAPGYNFGNSEVIVGQALKKLPREQVVVETKCGIVWERKGSLFNKVGD
                     RQLYKNLSPESIREEVAASLQRLGIDYIDIYMTHWQSVPPFFTPIAETVAVLNELKSE
                     GKIRAIGAANVDADHIREYLQYGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYS
                     PLEQGLLTGTITRDYVPGGARANKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLAL
                     AWILKQSDLISILSGATAPEQVRENVAALNINLSDADATLMREMAEALER"
     gene            9879..>10540
                     /locus_tag="RN951_003937"
     CDS             9879..>10540
                     /locus_tag="RN951_003937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDX2528864.1"
                     /translation="MAAKDRIQAIKQMVANDKKVTVSNLSGIFQVTEETIRRDLEKLE
                     DEGFLTRTYGGAVLNTAMLTENIHFYKRASSFYEEKQLIARKALPFIDNKTTMAADSS
                     STVMELLKLLQDRSGLTLLTNSAEAIHVLAQSEIKVVSTGGELNKNTLSLQGRITKEI
                     IRRYHVDIMVMSCKGLDINSGALDSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFV
                     QLA"
BASE COUNT         2788 a         2291 c         2686 g         2775 t
ORIGIN      
        1 aacgtttcgc aacgcgaatg gattgcgcca gatgtgcagg tttctctttg gtcacttttt
       61 gcgtttctga agcgtaagcc gtttctacac aaacaaatgt tttgtagcca tcatccggca
      121 tatcgcccat gctaattgaa agcgccggtc ccgggttcca gccgacaacg ttcagatgat
      181 gctggtggcc tacggcgata atacgattca gcgcttcatc attaatcacg ctgcaatctt
      241 gtggattcag atacacgcga tcggtacggt cagggaaggt ctgaatacca tcggtcagta
      301 cattttcttt cgcgtcattc actttatcaa tgaagcgatc gcccagccca ctgacgctta
      361 ccttagcgat atcacccacg ttaaagtagg tatgcagggc agaggtggtt tcaaattcgc
      421 catgtgattc aagatcgatt tcacaagttt tacccacgcg gaaatgcgct aacagcgtaa
      481 agtcgtgcgg ccagaatttt ttcgtctctt cgctttgcgt caattcaaaa gtcagcgcta
      541 cgccatcagc atcttcatga tgtgatttca gcgtccacgg caggttgcgg gcaaaaccgt
      601 gcgcaggcag accttgttgt gccgccggac caaaccacgg ccagcaaacc ggtacgccac
      661 cgcgaatagc gacgccattt ttgaacggtg tgttgttgct caaccacaga acttcttctt
      721 cacccgcagg tttccacgag agaaggtgtg cgccctgtaa tgcaaaagag gcttttacct
      781 ggggatgatc gaccacaatg aggtccagtt catccagttt acgacgggag aggacagggg
      841 agatttgttc gatgaccgga agggcaaaaa ttttcttaat catgacgcag tcctttaact
      901 tcattttatc aggtaaaaaa aagagcgacc gaagtcgctc tttttagatc acagtgtcat
      961 ctcaacttat ttggagatgt gagcgatcag gtccagaact ttgttggagt aaccggtttc
     1021 gttgtcgtac caggatacca gtttcacgaa gttgtcgttc agagcgatac cagctttagc
     1081 atcgaacacg gaagtgcaaa cttcgccgtt gaaatcggta gatactacgt catcttcggt
     1141 gtagcccaga acgcctttca tttcgccttc agcagcagct ttaacggcag ctttgatctg
     1201 ctcgtaagtt gcagcttttt ccagacgaac ggtcaggtca actacagata cgttcggggt
     1261 cggaacgcgg aacgccatac cagtcagttt gccattcagt tctggcagta ctttacctac
     1321 agctttagca gcaccggtag aggacgggat gatgttctgg gaagcgccgc ggccgccgcg
     1381 ccagtctttg tgagacgggc catcaacggt tttctgagta gcggtagtag cgtgaacggt
     1441 ggtcatcaga ccttcgatga tgccgaagtt atcgttgata actttagcca gcggagccag
     1501 gcagttggtg gtgcaggaag cgttggaaac gatgtcctgg ccagcatatt tgtcgaagtt
     1561 agcgccttta acgaacatcg gagtgttgtc tttagacgga ccagtcataa ccactttctt
     1621 cgcaccagcg gtgatgtgtt tacgagcagt ttcgtcagtc aggaacagac cagttgcttc
     1681 agcgacaacg tcaacaccaa cttcgtccca tttcaggtta gccggatcac gttcagcggt
     1741 aacacggatt tttttaccgt taacgatcag atgaccgtct ttcacttcaa cggtaccgtc
     1801 gaaacggccg tgagtggagt catatttcag catgtatgcc atgtaatcag cgtctaacag
     1861 gtcgttgatt gcaacgatct cgatgtcaga acgtttctga gcagcacgga aaacaatgcg
     1921 accgatacgg ccaaaaccgt tgatacctac tttgatagtc atatattcca ccagctattt
     1981 gttagtgaat aaaaggttgc ctgtaaaatt acaaaaacct tacgcagcgt caagcggaat
     2041 cgtgtcaatc attgcgacaa atcaatcctg tgcctaagca ttacgcgact gactcgcctc
     2101 actcttcctt tgggcttgag accacatggg gtcggcgccc cgaattttaa agggcaatta
     2161 cgataaaaat gtgattttca tcacgattta ggtgcagcca tttcgtcgag atcaagttta
     2221 ggacaaaatt ttgccagttg gtgttaatgt tttgttagaa tcagtcacgt aatgtgagca
     2281 cgattaaagt gagatgtgag caaatggcta ataaaccttc ggcagaagaa ctgaaaaaaa
     2341 atttgtccga gatgcagttt tacgtgacgc agaatcatgg gacagagccg ccatttacgg
     2401 gtcgtttact gcataacaag cgtgacggcg tatatcactg tttgatctgc gatgccccgc
     2461 tgtttcattc ccaaaccaag tatgattccg gctgtggctg gcccagtttc tacgaaccgg
     2521 taagtgaaga atccattcgt tatatcaaag acttgtcaca tggaatgcag cgcatagaaa
     2581 ttcgttgcgg taactgtgat gcccatctgg ggcatgtctt ccccgacggg ccgcagccaa
     2641 cgggcgaacg ttattgtgtt aactctgcct ctttacgctt taccgatggc gaaaacggcg
     2701 aagaaatcaa cggttgaaaa aacgattcag caacttattc cacaggagcg gaaaaattat
     2761 gaatcttgat gacattatca acagcatgat gcctgaggta taccagcgtt tgtcgaccgc
     2821 cgttgaactg gggaaatggc ctgatggcgt tgcgttgacc gaggaacaaa aagagaactg
     2881 cctgcaactg gtgatgctgt ggcaagcccg ccataatatc gaagcacagc atatgacaat
     2941 tgacacaaat ggtcagatgg tcatgaagag caaacagcag ttaaaagaag attttggtat
     3001 ctcagcaaag cctattgcca tgtttaagta agtggttcat cccctttttg cctcggctat
     3061 gaaggggata gccaacaatg accccacgac tcatctcaat tatctcgcca tgacctggct
     3121 aagtcccagt ccgatctctt gccgtcccgt tcacacctga atgacttctc ctgaacttaa
     3181 gtctcagacc tatttggccg gtaatccctc tcgaatttgc tctttttgcg ccccgccttc
     3241 catcaacctg taacagaccc agccattttc tgcgtaattg tgatctgagt tgtaaaacgc
     3301 agatcattat ctgtgtttta cagatttaat gttgacctca aaaatcatgt gggtaagtat
     3361 gatggccatc taagcaaaac taaacacaga ggatgacgca atgaaagcac tggctcggtt
     3421 tggcaaggcc tttggcggct acaagatgat tgatgtccca caacccatgt gtggcccgga
     3481 agatgtagtg attgaaatta aagccgcggc aatctgcggc gcagacatga agcactacaa
     3541 tgtcgatagc ggttctgatg agtttaactc tatccgcggc catgagttcg caggttgtat
     3601 tgcgcaggtt ggtgaaaaag tcaaagactg gaaagtgggg caacgcgtcg tatcggataa
     3661 cagcggtcac gtttgcggtg tttgtccggc ctgtgaacaa ggtgattttc tgtgttgtac
     3721 agaaaaagta aaccttggtc tggataataa tacctggggc ggtggttttt ccaaatattg
     3781 tctggttcct ggtgaaattc tcaaaattca tcgtcatgcg ttgtgggaaa tccctgatgg
     3841 tgttgattat gaggacgcag ccgtacttga ccctatctgt aatgcctaca aatccatcgc
     3901 gcagcaatcg aaattccttc ctggtcagga tgtggtcgtc atcggcactg gcccactcgg
     3961 gctgttctcc gtacaaatgg cgcgaattat gggggcggta aatatcgtcg tcgttggtct
     4021 gcaagaagat gtggcggtcc gcttcccggt tgcaaaagaa ctgggtgcga cggcagtagt
     4081 aaatggttct accgaagatg tggtggcgcg ctgccagcaa atttgtggca aagacaatct
     4141 gggactggtg attgaatgct ccggtgccaa tatcgcactg aaacaagcca tcgaaatgct
     4201 ccgcccgaac ggggaagtgg tacgcgttgg aatgggcttc aaacctcttg atttctcgat
     4261 taatgacatt accgcctgga acaaaagcat cattgggcat atggcctatg actccacctc
     4321 atggcgtaac gctatcaggc tattagccag cggcgctatc aaagtcaaac cgatgatcac
     4381 gcatcgtatc ggcctgtcgc aatggcgcga agggtttgat gcgatggtcg ataaaaccgc
     4441 aatcaaagtg atcatgactt acgactttga tgaataacca ctctcctgaa ggaacgttat
     4501 cgcatggaac agataacaaa accgcattgt ggtgcacggc tggatcgctt accggattgc
     4561 cgctggcatt catcaatgtt tgccatcgtc gcgtttggct tgcttgtctg ctggagtaat
     4621 gccgttggtg gcttgatcct cgcgcagctg aaagcgttgg gctggacaga taattccacc
     4681 acagccacat tctcagcaat cacgaccgcc ggaatgtttc tcggtgcgct ggtgggcggc
     4741 atcattggcg acaaaaccgg tcgcagaaat gcgttcatcc tctatgaggc cattcatatt
     4801 gcctcgatgg ttgtcggtgc tttctcaccg aatatggatt tccttattgc ctgccgtttt
     4861 gtgatgggag ttgggctggg agctttactg gttacgctgt ttgctggttt caccgaatat
     4921 atgcccggta gaaatcgtgg aacgtggtca agtcgggttt cctttattgg caactggtca
     4981 tatccgctct gttcattgat agcgatggga ctcacgccgc tgattagtgc agagtggaac
     5041 tggcgggtac aactgcttat ccctgcaata ttgtcgctta tcgctacggc gctggcctgg
     5101 cgctactttc ctgaatcccc gcgctggctg gaatcgcgcg gacggtatca ggaagccgag
     5161 aaagtcatgc ggagtataga agaaggcgtc atacgccaga cgggtaaacc tttgccgcct
     5221 gtggttattg ctgatgacgg taaagcgcca caagcggtgc cgtattcagc cttactgaca
     5281 ggagtattac tgaaacgcgt gatattaggc tcttgtgtgc tgattgccat gaacgttgtg
     5341 cagtacacac taattaactg gttgccaaca atattcatga cccaggggat taatttaaaa
     5401 gactcgattg ttttaaatac catgagtatg tttggcgcgc catttggtat ttttattgcc
     5461 atgctggtga tggataaaat tccgcgtaaa acaatgggtg tggggctatt aatcctgatt
     5521 gcggtgctcg gatatatcta ttcactgcaa accagtatgt tgctcataac gttgattggt
     5581 ttcttcctga ttactttcgt ctatatgtac gtttgctatg cctcggcagt gtatgtccct
     5641 gaaatctggc cgacagaggc caaactccgt ggctccggtc tggcgaatgc ggtagggcga
     5701 atcagtggta ttgccgcacc ttatgccgtt gcagtgctgc tcagtagtta tggcgttacg
     5761 ggagtcttta ttcttctggg ggcggtttca attattgtcg caattgctat cgccaccatt
     5821 ggaatcgaaa ccaaaggtgt ctccgttgaa agtttaagta ttgatgcagt agccaataaa
     5881 taatacgggt ggattcaaaa tgaaaaattc aaaagcaata ttgcaggtgc cgggcacaat
     5941 gaaaattatt tcagcagaaa taccagtgcc taaagaagat gaagttttga ttaaagtaga
     6001 atatgtcggt atttgtggtt cagatgtaca tggttttgaa tcaggcccgt ttattccgcc
     6061 taaagaccca aatcaagaaa ttggcctggg tcatgaatgc gccgggacgg ttgtggctgt
     6121 gggaagccgc gtgcgcaaat ttaaaccggg ggatcgggta aatatcgaac ctggcgttcc
     6181 ttgcggtcac tgtcgttact gtctggaagg caaatataac atctgcccgg acgttgattt
     6241 tatggcgaca caacccaact accgcggcgc attaacgcac tatctgtgtc atccggagag
     6301 ctttacttac aaactgcccg acaatatgga cacgatggaa ggggcgctgg tggagcctgc
     6361 cgcagtcggg atgcatgccg cgatgctggc agatgttaaa ccgggtaaga agataattat
     6421 tctgggagca ggttgtattg gtttgatgac gttgcaagcg tgcaaatgcc tgggagcaac
     6481 ggaaattgcc gtcgttgatg tgctggaaaa acgtctggca atggcggaac agcttggtgc
     6541 gacagtggtt attaacggcg caaaagaaga cactattgca cgctgtcagc aatttaccga
     6601 agacatgggc gcagatattg ttttcgaaac agcgggttct gcggtcaccg ttaaacaggc
     6661 accttatctg gtaatgcgcg gcggtaaaat tatgattgtt ggtactgtac ccggcgattc
     6721 ggcaatcaat ttcctcaaaa tcaatcgcga agtcactatc cagacggtat tccgctatgc
     6781 caatcgttat ccggtcacga ttgaagctat ttcttcaggg cgattcgatg tgaaatcgat
     6841 ggtgacgcat atttacgatt atcgggatgt acaacaggca tttgaagagt cagttaacaa
     6901 caaacgcgac attattaaag gcgttattaa aattagcgat taattaatac gggagaacag
     6961 aacatgctcg cagatatcag atattgggaa aacgatgcca caaataaaca ttatgcaatt
     7021 gcccatttta acgtatggaa tgcagaaatg ttgatgggcg ttatcgacgc agccgaagaa
     7081 gcgaaatccc cggttattat ttcttttggt acaggttttg tcggtaacac ctcatttgaa
     7141 gatttctctc acatgatggt atcaatggca caaaaagcaa cggtgccggt aataactcat
     7201 tgggatcatg gtcggagtat ggagattatt cataacgcct ggactcatgg tatgaattca
     7261 ttaatgcgtg atgcttccgc gtttgatttc gaagaaaata ttcgtttaac caaagaggct
     7321 gtcgatttct tccatccgct gggtattccg gtagaggcgg aattagggca tgtcggtaat
     7381 gaaaccgttt atgaggaagc gctggcgggc tatcactata ccgatcctga ccaggcggct
     7441 gaatttgttg aacgtacggg ctgtgattca ttggctgtcg ccatcggcaa ccagcatggg
     7501 gtttatacgt cagagccaca attgaacttt gaggtcgtca aacgcgtacg cgatgccgtt
     7561 tctgttccgc tggttttgca cggtgcatcg gggatcagtg atgccgacat taaaactgca
     7621 atttcgttgg gtatcgcgaa aatcaacatt catacggagc tctgtcaggc cgcaatggtt
     7681 gcagtgaaag aaaaccagga tcagcctttc ctgcatttag aacgtgaagt acgtaaagct
     7741 gtaaaagaac gggcattgga aaaaattaaa ctgttcggtt ctgatggcaa agcggaataa
     7801 tgatatggat aatctcgacg ttatttgtat aggtgccgct attgttgata ttccattgca
     7861 accggtcagt aaaaatatct ttgatgtgga ttcttatcct cttgaaagaa tcgcaatgac
     7921 caccgggggt gatgcaataa atgaagcaac aattatttct cgtctgggcc atcgcacagc
     7981 attaatgagt cgtattggta aagatgccgc agggcaattt attctcgacc attgccgcaa
     8041 agagaatatt gatattcaaa gcctgaagca ggacgtcagc atagatacct ctattaacgt
     8101 tggactggtg acggaggatg gcgagcggac gtttgtcaca aaccgtaatg gcagtctgtg
     8161 gaaattgaat attgacgatg ttgattttgc gcggttttct caggcgaaat tattatcact
     8221 ggccagtatt ttcaacagtc cactattgga tggtaaagcg ctaacagaaa tttttacgca
     8281 agctaaagcc cggcagatga ttatctgtgc cgatatgatc aaaccgcggt tgaatgaaac
     8341 gctggatgat atttgcgaag cattgagtta tgtcgattat ctgtttccta attttgccga
     8401 ggcaaaatta ctcaccggga aagagacact ggatgaaatt gctgactgct ttcttgcgtg
     8461 cggcgtaaaa acggtggtga ttaaaacggg taaagacggc tgctttatca agcgtggtga
     8521 catgacgatg aaggtgccgg cggtcgcagg aataaccgcc atcgacacca ttggcgcggg
     8581 cgataacttt gcttcaggtt ttattgcggc actgttagaa ggcaaaaatc tgcgtgaatg
     8641 cgcacgcttt gccaatgcaa cggcggctat ctcggttcta agcgtcggtg ccaccaccgg
     8701 cgtaaaaaac agaaagctgg tcgaacaatt gctggaagaa tacgaaggat aatgaaggca
     8761 aatgaaaaag atacctttag gcacaacgga tattacgctt tcgcgaatgg ggttggggac
     8821 atgggccatt ggcggcggtc ctgcatggaa tggcgatctc gatcggcaaa tatgtattga
     8881 tacgattctt gaagcccatc gttgtggcat taatctgatt gatactgcgc caggatataa
     8941 ctttggcaat agtgaagtta tcgtcggtca ggcgttaaaa aaactgcccc gtgaacaggt
     9001 tgtagtagaa accaaatgcg gcattgtctg ggaacgaaaa ggaagtttat tcaacaaagt
     9061 tggcgatcgg cagttgtata aaaacctttc cccggaatct atccgcgaag aggtagcagc
     9121 gagcttgcaa cgtctgggta ttgattacat cgatatctac atgacgcact ggcagtcggt
     9181 gccgccattt tttacgccga tcgctgaaac tgtcgcagtg cttaatgagt taaagtctga
     9241 agggaaaatt cgcgctatag gcgctgctaa cgtcgatgct gaccatatcc gcgagtatct
     9301 gcaatatggt gaactggata ttattcaggc gaaatacagt atcctcgacc gggcaatgga
     9361 aaacgaactg ctgccactat gtcgtgataa tggcattgtg gttcaggttt attccccgct
     9421 agagcaggga ttgttgaccg gcaccatcac tcgtgattac gttccgggcg gcgctcgggc
     9481 aaataaagtc tggttccagc gtgaaaacat gctgaaagtg attgatatgc ttgaacagtg
     9541 gcagccactt tgtgctcgtt atcagtgcac aattcccact ctggcactgg cgtggatatt
     9601 aaaacagagt gatttaatct ccattcttag tggggctact gcaccggaac aggtacgcga
     9661 aaatgtcgcg gcactgaata tcaacttatc ggatgcagac gcaacattga tgagggaaat
     9721 ggcagaggcc ctggagcgtt aaatactcaa cacgattcac ctctgtttct gtgaaaactg
     9781 tgatgaaaat ctgtgattca aacaggttat tttgaaagta aacatcggtt atgcgataat
     9841 cgcgctaatg tgatgtaaaa agatacaggg gtgtaatcgt ggcggcaaaa gacaggattc
     9901 aggcaattaa gcaaatggtt gccaacgata aaaaggtgac agtctcaaat ttgagtggga
     9961 tttttcaggt aaccgaagaa accattcgcc gcgatcttga gaagctggaa gatgaaggct
    10021 ttttgaccag aacctatggt ggtgctgttt taaatacagc gatgttgacg gagaatatcc
    10081 atttttataa gcgcgcttca tcgttttatg aagagaagca gcttattgca cgcaaggcac
    10141 taccctttat cgacaataaa accaccatgg cagccgattc cagtagtacc gtaatggaat
    10201 tgctcaaatt gttacaggac cgtagtggcc tgacgttgct aaccaactcg gcggaagcga
    10261 ttcatgttct ggctcagtca gaaattaaag tcgtttcaac gggtggggaa ctaaacaaaa
    10321 atacactttc actgcaagga agaattacta aagagatcat caggcgctat catgtcgata
    10381 tcatggtaat gagttgtaaa ggtcttgata ttaacagcgg cgcgctggac tctaatgaag
    10441 cggaagctga aatcaaaaag acaatgatcc gtcaggcgac agaagttgcg ttattggttg
    10501 atcactctaa gtttgatcgc aaagcttttg tccagttagc
//
LOCUS       DAPOAV010000122        10222 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.122, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000122 DAPOAV010000000
VERSION     DAPOAV010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10222
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.122"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            389..1366
                     /gene="csiD"
                     /locus_tag="RN951_003938"
     CDS             389..1366
                     /gene="csiD"
                     /locus_tag="RN951_003938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311547.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation induced protein CsiD"
                     /protein_id="HDX2528865.1"
                     /translation="MNALTAVHNNAVDSGQDYSGFTLIPSAQSPRLLELTFTEQTTKQ
                     FLEQVAEWPVQALEYKSFLRFRVGKILDDLCANQLQPLLLKTLLNRAEGALLINAVGI
                     DDVAQADEMVKLATAVAHLIGRSNFDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELH
                     NDGTYVEEITDYVLMMKIDEQNMQGGNSLLLHLDDWEHLDHYFRHPLARRPMRFAAPP
                     SKNVSKDVFHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDAIETSKGILSVP
                     VPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYATHHYQTHQ"
     gene            1386..2654
                     /gene="lhgO"
                     /locus_tag="RN951_003939"
     CDS             1386..2654
                     /gene="lhgO"
                     /locus_tag="RN951_003939"
                     /EC_number="1.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417146.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-hydroxyglutarate oxidase"
                     /protein_id="HDX2528866.1"
                     /translation="MYDFVIIGGGIIGMSTAMQLIDVYPDARIALLEKESGPACHQTG
                     HNSGVIHAGVYYTPGSLKAQFCLAGNRATKAFCDQNDIRYDNCGKMLVATSDLEMEQM
                     RALWERTAANGIEREWLNAEELREREPNITGLGGIFVPSSGIVSYREVTAAMAKIFQA
                     RGGEIIYNAEVSALSEHKNGVVVRTRQGGEYEASTLISCSGLMADRLVKMLGLEPGFI
                     ICPFRGEYFRLAPEHNQIVNHLIYPIPDPAMPFLGVHLTRMIDGSVTVGPNAVLAFKR
                     EGYRKRDFSFSDTLEILGSSGIRRVLQNHLRSGLGEMKNSLCKSGYLRLVQKYCPRLS
                     LSDLQPWPAGVRAQAVSPDGKLIDDFLFVTTPRTIHTCNAPSPAATSAIPIGAHIVSK
                     VQTLLASQSNPGRTLRAARSVDALHAAFNQ"
     gene            2677..4125
                     /gene="gabD"
                     /locus_tag="RN951_003940"
     CDS             2677..4125
                     /gene="gabD"
                     /locus_tag="RN951_003940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HDX2528867.1"
                     /translation="MKLNDSNLFRQQALINGEWLDANNGEVIDVTNPANGDKLGSVPK
                     MGADETRAAIDAANHALPAWRALTAKERANILRNWFNLMMEHQDDLARLMTLEQGKPL
                     AEAKGEISYAASFIEWFAEEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPA
                     AMITRKAGPALAAGCTMVLKPASQTPFSALALAELAIRAGIPAGVFNVVTGSAGAVGN
                     ELTSNPMVRKLSFTGSTEIGRHLMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEG
                     ALASKFRNAGQTCVCANRLYVQDGVYDRFAEKLQQAVSKLHIGDGLDKGVTIGPLIDE
                     KAVAKVEEHIADALEKGARVVCGGKADERGGNFFQPTILVDVPANAKVSKEETFGPLA
                     PLFRFKDEADVIAQANDTEFGLAAYFYARDLSRVFRVGEALEYGIVGINTGIISNEVA
                     PFGGIKASGLGREGSKYGIEDYLEIKYMCIGL"
     gene            4139..5419
                     /gene="gabT"
                     /locus_tag="RN951_003941"
     CDS             4139..5419
                     /gene="gabT"
                     /locus_tag="RN951_003941"
                     /EC_number="2.6.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-aminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="HDX2528868.1"
                     /translation="MSSNKELMQRRSQAIPRGVGQIHPIFADRAENCRVWDVEGREYL
                     DFSGGIAVLNTGHLHPKVVAAVEAQLKKLSHTCFQVLAYEPYLELCEIMNQKVPGDFA
                     KKTLLVTTGSEAVENAVKIARAATKRSGTIAFSGAYHGRTHYTLALTGKVNPYSAGMG
                     LMPGHVYRALYPCPLHGISEDDAIASIHRIFKNDAAPEDIAAIVIEPVQGEGGFYAAS
                     PAFMQRLRALCDEHGIMLIADEVQSGAGRTGTLFAMEQMGVAPDLTTFAKSIAGGFPL
                     AGVTGRAEVMDAVAPGGLGGTYAGNPIACVAALEVLKVFEQENLLQKANDLGQKLKDG
                     LLVIAEKHPEIGDVRGLGAMIAIELFEDGDHSKPDAKLTAEIVARARDKGLILLSCGP
                     YYNVLRILVPLTIEDAQIRQGLEIISQCFAEAKQ"
     gene            5730..7130
                     /gene="gabP"
                     /locus_tag="RN951_003942"
     CDS             5730..7130
                     /gene="gabP"
                     /locus_tag="RN951_003942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GABA permease"
                     /protein_id="HDX2528869.1"
                     /translation="MGQSSQPHELGGGLKSRHVTMLSIAGVIGASLFVGSSVAIAEAG
                     PAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGRWAGYTIGWLYWWFW
                     VLVIPLEANIAAMILHSWVPGIPIWLFSLVITLALTGSNLLSVKNYGEFEFWLALCKV
                     IAILAFIFLGAVAISGFYPYAEVSGISRLWDSGGFMPNGFGAVLSAMLITMFSFMGAE
                     IVTIAAAESDTPEKHIVRATNSVIWRISIFYLCSIFVVVALIPWNMPGLKAVGSYRSV
                     LELLNIPHAKLIMDCVILLSVTSCLNSALYTASRMLYSLSRRGDAPAVMGKINRSKTP
                     YVAVLLSTGAAFLTVVVNYYAPAKVFKFLIDSSGAIALLVYLVIAVSQLRMRKILRAE
                     GSEIRLRMWLYPWLTWLVIGFITFVLVVMLFRPAQQLEVISTGLLAIGIICTVPIMAR
                     WKKLVLWQKTPVHNTR"
     gene            7151..7813
                     /gene="csiR"
                     /locus_tag="RN951_003943"
     CDS             7151..7813
                     /gene="csiR"
                     /locus_tag="RN951_003943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311552.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CsiR"
                     /protein_id="HDX2528870.1"
                     /translation="MTITSLDGYRWLKNDIIRGNFQPDEKLRMSLLTSRYALGVGPLR
                     EALSQLVAERLVTVVNQKGYRVASMSEQELLDIFDARANMEAMLVSLAIARGGDEWEA
                     DVLAKAHLLSKLEACDASEKMLDEWDLRHQAFHTAIVAGCGSHYLLQMRERLFDLAAR
                     YRFIWLRRTVLSVEMLEDKHDQHQTLTAAVLARDTARASELMRQHLLTPIPIIQQAMA
                     GN"
     gene            complement(7814..8263)
                     /gene="kbp"
                     /locus_tag="RN951_003944"
     CDS             complement(7814..8263)
                     /gene="kbp"
                     /locus_tag="RN951_003944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium binding protein Kbp"
                     /protein_id="HDX2528871.1"
                     /translation="MGLFNFVKDAGEKLWDAVTGQHDKDDQAKKVQEHLSKTGIPDAD
                     KVNIQIADGKATVTGDGLSQEAKEKILVAVGNISGIASVDDQVKTATPATASQFYTVK
                     SGDTLSAISKQVYGNANLYNKIFEANKPMLKSPDKIYPGQVLRIPEE"
     gene            complement(8347..8505)
                     /locus_tag="RN951_003945"
     CDS             complement(8347..8505)
                     /locus_tag="RN951_003945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaE/Pmp3 family membrane protein"
                     /protein_id="HDX2528872.1"
                     /translation="MGFWRIVITIILPPLGVLLGKGFGWAFIINILLTLLGYIPGLIH
                     AFWVQTRD"
     gene            8688..8987
                     /locus_tag="RN951_003946"
     CDS             8688..8987
                     /locus_tag="RN951_003946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX2528873.1"
                     /translation="MTELAQLQASAEQAAALLKAMSHPKRLLILCMLSGSPGTSAGEL
                     TRITGLSASATSQHLARMRDEGLIDSQRDAQRILYSIKNEAVNAIIATLKNVYCP"
     gene            8997..9521
                     /gene="ygaP"
                     /locus_tag="RN951_003947"
     CDS             8997..9521
                     /gene="ygaP"
                     /locus_tag="RN951_003947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase YgaP"
                     /protein_id="HDX2528874.1"
                     /translation="MALTTISPHDAQELIARGAKLIDIRDADEYLREHIPEADLAPLS
                     VLEQSGLPPKLRREQIIFHCQAGKRTSNNADKLAAIAAPAEIFLLEDGIDGWKRAGLP
                     VAVNKSQPLPLMRQVQIAAGGLILIGVVLGYTVNSGFFLLSGFVGAGLLFAGISGFCG
                     MARLLDKMPWNQRA"
     gene            complement(9568..9972)
                     /gene="stpA"
                     /locus_tag="RN951_003948"
     CDS             complement(9568..9972)
                     /gene="stpA"
                     /locus_tag="RN951_003948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein StpA"
                     /protein_id="HDX2528875.1"
                     /translation="MSVMLQSLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEE
                     EQQQRELAERQEKISTWLELMKADGINPEELLGNSSAAAPRAGKKRQPRPAKYKFTDV
                     NGETKTWTGQGRTPKPIAQALAEGKSLDDFLI"
BASE COUNT         2372 a         2610 c         2760 g         2480 t
ORIGIN      
        1 gcgctcttct tttagggaaa acaggagaac cgccgaacta tctctattta taatttaatg
       61 ttatatctgc cccgataaaa cggggcagat aatatgttta gtttactaac ggtcattttg
      121 cagtgaagcc atttactgtt ttttatcgac cagataatct gttctctaat gttaactccc
      181 cctaacctgt tgctttagtt attcatttcc tgtctcactt tgccttaata ccctacgtta
      241 aatgttacta atttgttgct tttgatcaca ataagaaaac aatatgtcgc ttttgtgcgc
      301 atttttcaga aatgtagata tttttagatt atggctacga aatgagcatc gccatgtcac
      361 cctacatctc ataagaggat cgcttctgat gaatgcactg accgccgtac acaataacgc
      421 tgtcgattca ggccaggact atagcggatt cactctcatc ccgtcggcgc aatccccgcg
      481 tctgctggaa ctcaccttca ccgaacagac gaccaaacag tttctcgaac aggttgccga
      541 atggcccgtg caggcgctgg agtacaaatc gtttctgcgt tttcgggtag gcaaaattct
      601 tgacgatctg tgtgcgaatc agctgcaacc attgctgttg aagaccctgc taaaccgtgc
      661 tgaaggtgcg ctgttgatca atgcggtggg tatcgatgat gtggcgcagg cagatgagat
      721 ggtgaagctg gcaacggcgg tagcgcatct gattggtcgc tcaaatttcg atgcgatgag
      781 cggtcagtat tacgcgcgtt tcgtggtgaa aaatgtcgat aactcagaca gctatctgcg
      841 tcagccgcac cgcgtgatgg aactgcacaa cgacggcacg tatgtcgaag agatcaccga
      901 ttacgtgctg atgatgaaaa tcgatgagca aaacatgcag ggtggaaatt cgttgctgct
      961 gcatctcgat gactgggaac atctggacca ctatttccgc catccactgg cgcgtcgccc
     1021 gatgcgcttt gccgcgccgc cgagcaaaaa cgtcagcaaa gatgttttcc atccagtgtt
     1081 cgacgttgat caacagggtc gcccggtgat gcgctatatc gaccagttcg tccagccaaa
     1141 agattttgaa gaaggcgtgt ggttgagcga gctttccgat gccattgaaa ccagcaaagg
     1201 cattctttct gtacccgttc ccgttggcaa attcctgttg ataaacaacc tgttctggct
     1261 gcacggtcgc gaccgcttta ctccgcaccc ggatctgcgc cgtgaactga tgcgtcagcg
     1321 tggctatttc gcttacgcca ctcaccacta ccagacgcat cagtaagcgc aaaggaattg
     1381 agcggatgta tgattttgtg attattggcg gcggcatcat cggcatgtcg accgccatgc
     1441 aactgattga tgtttatccg gatgcccgca ttgcgttgct ggaaaaagag tccggcccgg
     1501 cctgtcacca gacgggccac aacagcggcg tgatccatgc cggggtctat tacacgcccg
     1561 gcagcctgaa ggcgcagttt tgcctggcgg gaaaccgcgc caccaaagcc ttttgcgatc
     1621 aaaacgacat tcgctatgac aactgcggca agatgctggt cgccacgtcc gatctcgaaa
     1681 tggaacagat gcgcgcgttg tgggaacgca cggcggcgaa cggtatcgag cgcgagtggt
     1741 taaacgccga ggaactgcgc gagcgcgaac cgaatatcac cgggctcggc ggcatttttg
     1801 tgccgtccag cggcattgtc agctatcgcg aagtcacagc ggcaatggca aaaatcttcc
     1861 aggccagagg cggtgagatt atttataacg ccgaagtcag cgccctcagt gagcataaaa
     1921 acggcgtggt cgtccgaacc cgtcagggcg gcgaatatga agcatcgacg ctgattagct
     1981 gttccgggct gatggctgac cggctggtga aaatgctcgg cctcgaaccg ggttttatta
     2041 tctgcccgtt ccgtggcgag tatttccgcc ttgcgccgga gcataaccag attgttaacc
     2101 atctgattta ccccattccc gacccggcaa tgccattttt gggcgtgcat ctcacccgaa
     2161 tgatcgatgg cagcgtcacc gtcgggccaa acgcggtgct ggctttcaaa cgcgaaggct
     2221 atcgcaagcg cgacttctca tttagcgaca cgctggagat tttgggctcg tcggggattc
     2281 gccgggtgct gcaaaaccat ctacgctcag gactgggcga gatgaaaaac tcgctgtgca
     2341 aaagcggcta tctgcgcctg gtgcaaaagt attgtccccg gctttcgtta agcgatctcc
     2401 agccctggcc cgccggtgtg cgggcgcagg cagtatcgcc ggacggcaag ctgattgacg
     2461 attttctgtt tgtcaccacc ccacgcacga tccacacctg caatgcgccc tccccggcag
     2521 cgacatcagc aattcctatt ggtgcgcata ttgtcagcaa ggtacaaacg ctgttggcaa
     2581 gccagagtaa ccccggacgc acgctgcgag cggcacgtag tgtggatgcc ttacacgccg
     2641 catttaatca ataacctttg aaaacaggac gtaacaatga aacttaacga cagtaactta
     2701 ttccgccagc aggcgttgat taacggggaa tggctggacg ccaacaatgg tgaagtcatc
     2761 gacgtcacca atccggcgaa cggcgacaag ctgggtagcg tgccgaaaat gggcgctgat
     2821 gaaacccgcg ccgctatcga cgccgccaac cacgccctgc ccgcctggcg tgcgctcacc
     2881 gccaaagaac gcgccaacat tctgcgcaac tggttcaatt tgatgatgga gcatcaggac
     2941 gatttagcgc gcctgatgac cctcgaacag ggcaaaccac tggccgaagc gaaaggtgaa
     3001 atcagctacg ccgcctcttt tattgagtgg tttgccgaag aaggcaaacg catttatggc
     3061 gacaccattc ccggtcatca ggccgataaa cgcctgattg ttatcaagca gccgattggc
     3121 gttaccgcag ctatcacgcc gtggaacttc ccggcggcga tgattacccg taaagccggt
     3181 ccggcgctgg cggcaggctg caccatggtg ctgaagcccg ccagtcagac accgttctct
     3241 gcgctggcgc tggcggagct ggcgattcgc gcgggcattc cggctggcgt gtttaacgtg
     3301 gtcaccggtt cggcaggcgc ggtcggtaat gaactgacca gcaacccgat ggtacgcaaa
     3361 ctgtcgttta ccggttcgac cgaaattggc cgccatttaa tggaacagtg cgcgaaagac
     3421 atcaaaaaag tgtcgctgga gctgggcggc aacgcgccgt ttatcgtctt tgacgatgcc
     3481 gatctcgata aagccgtgga aggcgcgctg gcctcgaaat tccgcaacgc cgggcaaacc
     3541 tgcgtctgcg ccaaccgttt atacgtgcag gacggcgtgt atgaccgctt tgccgaaaaa
     3601 ctacagcagg cggtgagcaa actgcacatc ggcgacgggc tggataaagg cgtcaccatc
     3661 gggccgctga tcgatgaaaa agcggtagca aaagtggaag agcatattgc cgatgcgctg
     3721 gagaaaggtg cgcgtgtggt ttgcggcggt aaagcggatg aacgcggcgg caacttcttc
     3781 cagccgacca ttctggtgga cgtgccggcc aacgccaaag tgtcgaaaga agagacgttc
     3841 ggccccctcg ccccgctgtt ccgctttaaa gatgaagccg atgtgattgc gcaagccaat
     3901 gacaccgagt ttggccttgc cgcctatttc tacgcccgtg atttaagccg cgtcttccgc
     3961 gtgggcgaag cgctggagta cggcatcgtc ggcatcaata ccggcattat ttccaatgaa
     4021 gtggccccgt tcggcggcat caaagcctcg ggtctgggtc gtgaaggttc gaagtatggc
     4081 atcgaagatt acttagaaat caaatatatg tgcatcggtc tttaactgga gaacgcgaat
     4141 gagcagcaat aaagagttaa tgcagcgccg cagtcaggcg attccccgtg gcgttgggca
     4201 aattcacccg attttcgctg accgcgcgga aaactgccgg gtgtgggacg ttgaaggccg
     4261 tgagtatctt gatttctcgg gcgggattgc ggtgctcaat accgggcacc tgcatccgaa
     4321 ggtggtggcc gcggtggaag cgcagttgaa aaaactgtcg cacacctgct tccaggtgct
     4381 ggcttacgag ccgtatctgg agctgtgcga gattatgaat cagaaggtgc cgggcgattt
     4441 cgccaagaaa acgctgctgg ttacgaccgg ttccgaagcg gtggaaaacg cggtaaaaat
     4501 cgcccgcgcc gccaccaaac gtagcggcac catcgctttt agcggcgcgt atcacgggcg
     4561 cacgcattac acgctggcgc tgaccggcaa ggtgaatccg tactctgcgg gcatggggct
     4621 gatgccgggt catgtttatc gcgcgcttta tccttgcccg ctgcacggca taagcgagga
     4681 tgacgctatc gccagcatcc accggatctt caaaaatgat gccgcgccgg aagatatcgc
     4741 cgccatcgtg attgagccgg ttcagggcga aggcggtttc tacgccgcat cgccagcctt
     4801 tatgcagcgt ttacgcgcgc tgtgtgacga gcacgggatc atgctgattg ccgatgaagt
     4861 gcagagcggc gcggggcgta ccggcacgct gtttgcgatg gagcagatgg gcgttgcgcc
     4921 ggatctcacc acctttgcga aatcgatcgc gggcggcttc ccgctggcgg gcgtcaccgg
     4981 gcgcgcggaa gtgatggatg ccgtcgctcc aggcggtctg ggcggcacct atgccggtaa
     5041 cccgattgcc tgcgtggcag cgctggaagt gttgaaggtg ttcgagcagg aaaatctgct
     5101 gcaaaaagcc aacgatctgg ggcagaagtt gaaagacgga ttgctggtga tagccgaaaa
     5161 acacccggag atcggcgacg tacgcgggct gggagcgatg attgccatcg agctgtttga
     5221 agatggcgat cacagcaaac cggacgcaaa actcaccgcc gagatcgtgg cacgcgcccg
     5281 cgataaaggc ctgattcttc tctcctgcgg cccgtattac aacgtgctgc gcatccttgt
     5341 accgctcacc attgaagacg ctcagatccg tcagggtctg gagatcatca gccagtgttt
     5401 tgctgaggcg aagcagtagc tatgtccgtt tgtaagagtt aaacgttgct aagggaatga
     5461 taacgatgca gtaaaaaata ataacgatga ggcgatcgac aaagttaaaa acgactgcgg
     5521 actgtcccct cgcccctctg gggagagggt tagggtgagg ggtaatcacg cggctacacc
     5581 ctcaccccgg ccctctccct aagggagagg gagaaaaccc tcccgctttc gtttttaaga
     5641 ttttgttgac cgtctcaatt aaacgcgtga cccggcgcgg gaaatgtcgg ggcgctctcc
     5701 caagtgacac actttcgaga ggattcagga tggggcaatc atcgcaacca catgagttag
     5761 gcggcgggct gaagtcacgc cacgtcacca tgttgtctat tgccggtgtt atcggcgcaa
     5821 gtctgtttgt cggttccagc gtcgccatcg ccgaagcggg cccggcggta ttactggcct
     5881 atctgttcgc cggattactg gtggttatga ttatgcgaat gctggcggaa atggcggttg
     5941 ccacgcccga taccggttcg ttttccacct atgccgataa agccattggc cgctgggcgg
     6001 gttataccat cggctggctg tactggtggt tttgggtact ggttatcccg ctggaagcca
     6061 acatcgccgc tatgatcctg cactcgtggg ttccaggcat tcccatctgg ttattttccc
     6121 tcgtcattac cctcgcctta actggcagta atttattaag cgttaaaaac tacggcgaat
     6181 ttgagttctg gctggcgctg tgcaaagtca tcgctatcct ggcctttatt ttccttggtg
     6241 cagtcgcaat tagcggtttt tacccttatg ccgaagtgag cgggatctca agattgtggg
     6301 atagcggcgg ctttatgccc aacggcttcg gtgcggtatt aagcgcgatg ttgatcacca
     6361 tgttctcgtt tatgggcgca gaaattgtca ccattgccgc cgcggaatcc gacacgccgg
     6421 aaaaacatat tgtccgcgct accaactcgg ttatctggcg tatttctatc ttctatttgt
     6481 gctctatttt tgtcgtagtg gcgttaatac cgtggaatat gccggggctg aaagccgttg
     6541 gttcttatcg ctcggttctg gaattgctca atattcccca tgcgaaatta atcatggact
     6601 gcgtgatatt actttccgta accagctgtc tgaactcggc gctgtatacc gcgtcaagga
     6661 tgctctactc cttaagccgt cgcggtgatg cgcccgcggt aatgggcaaa atcaaccgca
     6721 gtaaaacccc gtatgtggcg gtgttactct ccaccggagc ggcattttta acggtggtgg
     6781 tgaactatta cgcacctgcg aaagtgttta aattcctgat agacagctcc ggtgctatcg
     6841 ccctgctggt ttatttagtc atcgccgttt cacagttgcg gatgcgtaaa attctgcgag
     6901 cagaaggaag cgaaattcgc ttgcgcatgt ggctttaccc gtggctcacc tggctggtaa
     6961 taggctttat tacctttgtg ttggtggtga tgttattccg cccggcgcaa cagttagaag
     7021 tgatctctac cggcttatta gcgataggga ttatctgtac cgtgccgatt atggcgcgct
     7081 ggaaaaagct ggtattgtgg caaaaaacac ccgttcataa tacgcgctga taatgatcag
     7141 gagtcacacc atgaccatta cgtctctgga tggctatcgc tggctgaaga acgatattat
     7201 tcgcggtaat tttcaaccgg atgaaaaatt acgaatgagt ttgctgacat cgcgttatgc
     7261 acttggcgtt gggccgttac gggaagctct ttcgcaactg gtggcggaac ggctggtcac
     7321 ggtggtgaat caaaaagggt atcgggtggc gtctatgtca gagcaggagc tgctcgatat
     7381 tttcgacgcc cgcgccaata tggaagcgat gctggtcagt ctggcgattg cccgcggtgg
     7441 cgatgaatgg gaggcagacg ttctcgcaaa agcgcatctg ctgagtaagc tggaggcctg
     7501 tgacgccagc gagaaaatgc ttgatgagtg ggatctgcgt catcaggcgt ttcatacagc
     7561 aattgtggcg ggctgtggtt ctcactattt gctgcaaatg cgtgaacggt tgtttgatct
     7621 ggcggcgcgc tatcgattta tctggctgcg gcgaacggtg ctttcggtag aaatgctgga
     7681 ggataaacac gatcagcacc agaccctgac tgcggcggta ctggcgcgag ataccgcgcg
     7741 cgccagtgag ttaatgcgcc agcatttact gacgccaatt cccattatcc agcaggcgat
     7801 ggctggcaat taactactct tccggaatac gcaacacttg ccccggataa attttatccg
     7861 ggctttttag catcggttta ttcgcttcga agattttatt gtacagatta gcgttaccgt
     7921 agacctgttt ggaaatggca ctcagagtgt cgccagactt aacggtataa aactggctgg
     7981 cagtggctgg tgtcgccgtt ttcacctgat catcaacact ggcaataccg gaaatattcc
     8041 ccaccgcaac aaggattttc tccttcgcct cctgactcag gccgtcacca gtgaccgtcg
     8101 ctttgccgtc ggcaatttga atgttcactt tatcggcatc aggtataccg gttttgctca
     8161 gatgctcctg caccttcttc gcctgatcgt ctttatcgtg ctgacctgta accgcgtccc
     8221 agagtttttc tccggcatct ttcacaaaat tgaacagacc catagctacc tcattcgtta
     8281 acggaaacac tcagaaagtg tagcagagga acgcggcgcg ttaacgccgc gggggtgagc
     8341 acaggtttaa tcgcgggttt gcacccagaa cgcgtgaatc aaaccgggga tatacccaag
     8401 cagtgtcagc agaatattaa taatgaacgc ccaaccgaac cctttaccga gcagcacgcc
     8461 gagaggcggc agaatgatgg tgatgacgat tctccagaaa cccatatgta ctccctataa
     8521 gaaaattact cattgtttaa aaagagattt tatctcttaa gcgtagtaat tttagcggag
     8581 cctgccagtt tcagcttacg cttttactct catttacgct gctgatgctg gtatatgttg
     8641 catttttagt ttagagttta cttaatttag aaaatactta aataaatatg actgaactcg
     8701 cgcaattaca ggccagtgcc gaacaggcag cggccttatt gaaagcaatg agccatccta
     8761 aacgattgct gattctgtgc atgcttagcg gttcccccgg caccagcgcg ggagagctga
     8821 cgcgcattac cggactgagt gcctctgcga catcacagca tctcgctcgt atgcgggacg
     8881 aagggcttat cgacagccaa cgggatgccc aacgcattct atattccatt aaaaatgagg
     8941 cggtaaatgc cattatcgcc accctgaaaa atgtctattg tccgtaagga gtcactatgg
     9001 ctttgacaac catttcgccg catgatgcac aagaattaat cgcacgcggc gcaaagttaa
     9061 tcgatattcg tgatgctgat gaatatcttc gtgaacatat tcctgaagca gatctggctc
     9121 cattatccgt gctggaacag tcaggtcttc cacctaaatt acgtcgcgag caaattatat
     9181 tccactgcca ggcaggtaaa cgcaccagta ataacgccga taaattagca gcgattgccg
     9241 cccccgcaga aatattttta ctcgaagatg ggattgatgg ctggaaaaga gctggattgc
     9301 cagtagcggt aaataaatct caacccttgc cgttaatgcg ccaggtgcag atcgctgcgg
     9361 gtggtttaat attaatcggc gttgtactgg gttataccgt aaatagcggt ttcttcttat
     9421 taagtggctt tgttggtgcc gggttactgt ttgcaggaat cagcggtttt tgtggaatgg
     9481 caaggttgtt agataagatg ccgtggaacc aacgagcttg agaagcgacg ccggacgcgc
     9541 cctagcagcg acatccggcc tcagtaatta gatcaggaaa tcgtcgagag atttaccttc
     9601 tgccagcgcc tgagcaattg gcttcggtgt acggccctga ccggtccagg ttttagtttc
     9661 accgttaaca tcggtgaatt tatatttcgc cggacgcggc tggcgttttt taccagcgcg
     9721 tggtgcagca gcagagctat tacccaataa ctcttccggg ttaattccgt cagccttcat
     9781 cagctccagc caggtgctaa ttttttcctg acgctcagcc agttcacgct gctgctgttc
     9841 ttcttcttca cgtctttctt tagtgacaac cctgaatttt tcgagcattt cttcaagaac
     9901 gtcaatggag aattcgcgag ccatcgcacg gagggtgcga atgttattta aactttgtaa
     9961 cattacggac ataataaaga aaacctttta acgccaaaac aaaaaagtat ttcgtcgcgt
    10021 agtgtaagcg atcacttatt atatttccac aaaatttaat ctatttacag tcctgcgcga
    10081 gattatttca gctgttattt tctgaaactc tcagaataat ttcaagatta tatattagcc
    10141 attttgatga gtaatttaga ttattggtga acagagtggc gctctctgct cgctaattcc
    10201 gcaagcctga caaaaccgaa gt
//
LOCUS       DAPOAV010000123        10182 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.123, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000123 DAPOAV010000000
VERSION     DAPOAV010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10182
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.123"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(37..273)
                     /locus_tag="RN951_003949"
     CDS             complement(37..273)
                     /locus_tag="RN951_003949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313355.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1435 domain-containing protein"
                     /protein_id="HDX2528876.1"
                     /translation="MLQRMLGSGWGVLLPGLLIAGLMYADLSPDQWRIVILMGLVLTP
                     VMLYHKQLRHYILLPSCLALIAGIMLMIVNLNQG"
     gene            414..1202
                     /gene="fhuF"
                     /locus_tag="RN951_003950"
     CDS             414..1202
                     /gene="fhuF"
                     /locus_tag="RN951_003950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore-iron reductase FhuF"
                     /protein_id="HDX2528877.1"
                     /translation="MAYRSAPLYEDIIWRTHLQPQDAGLAQAVRATIAEHREHLLEFI
                     RLDEPAPLRAMTLAQWSSPNTLSSLLAVYSDHIYRNQPTMIRENKPLISLWAQWYIGL
                     MVPPLMLALLTQEKALDVTPEHFHVEFHETGRAACFWVDVCEDKNATLHSPQQRMETL
                     ISQALVPVVQALEATGEINGKLIWSNTGYLINWYLTEMKQLLGEATVESLRHALFFEK
                     TLTNGEDNPLWRTVVLRDGLLVRRTCCQRYRLPDVQQCGDCTLK"
     gene            complement(1240..1917)
                     /gene="bglJ"
                     /locus_tag="RN951_003951"
     CDS             complement(1240..1917)
                     /gene="bglJ"
                     /locus_tag="RN951_003951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418786.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator BglJ"
                     /protein_id="HDX2528878.1"
                     /translation="MEHSRIKKRNVALIEKCVMSSIGIESLFRKFAGNPYKLHTYTSQ
                     ESFQDAMSRISFAAVIFSFSAMRSERREGLSCLTELAIKFPRTRRLVIADDDIEARLI
                     GSLSPSPLDGVLSKASTLEIFHQELFLSLNGVRQATDRLNNQWYINQSRTLSPTEREI
                     LRFMSRGYSMTQIAEQLKRNIKTIRAHKFNVMSKLGVSSDAGLLEAADILLCMRHCEA
                     SNVLHPY"
     gene            complement(1875..2600)
                     /locus_tag="RN951_003952"
     CDS             complement(1875..2600)
                     /locus_tag="RN951_003952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDX2528879.1"
                     /translation="MLPGCCKNGIVISKIPVMQAGLKEVMRTHFPEYEIISSASAEDL
                     TLLQLRRSGLVIADLAGESEDPRSVCEHYYSLISQYREIHWVFMVSRSWYSQAVELLM
                     CPTATLLSDVEPIENLVKTVRSGNTHAERISAMLTSPAMTETHDFSYRSVILTLSERK
                     VLRLLGKGWGINQIASLLKKSNKTISAQKNSAMRRLAIHSNAEMYAWINSAQGARELN
                     LPSVYGDAAEWNTAELRREMSHS"
     gene            3219..3989
                     /locus_tag="RN951_003953"
     CDS             3219..3989
                     /locus_tag="RN951_003953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418784.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter ThrE family protein"
                     /protein_id="HDX2528880.1"
                     /translation="MQTEQQRAVTRLCIQCGLFLLQHGAESALVDELSSRLGRALGMD
                     SVESSISSNAIVLTTIKDGQCLTSTRKNQDRGINMHVVTEVQHIVILAEHHLLDYKGV
                     EKRFSQIQPLRYPRWLVALMVGLSCACFCKLNKGGWDGAVITFFASTAAMYIRQLLAQ
                     RHLHPQINFCLTAFAATTISGLLLQLPTFSNTPTIAMAASVLLLVPGFPLINAVADMF
                     KGHINTGLARWAIASLLTLATCVGVVMALTIWGLRGWV"
     gene            3980..4453
                     /locus_tag="RN951_003954"
     CDS             3980..4453
                     /locus_tag="RN951_003954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418783.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HDX2528881.1"
                     /translation="MGVIEFLFTLAQDMILAAIPAVGFAMVFNVPVRALRWCALLGAI
                     GHGSRMILMTSGLNIEWSTFMASMLVGTIGIQWSRWYLAHPKVFTVAAVIPMFPGISA
                     YTAMISAVKISQLGYSESLMITLLTNFLTASSIVGALSIGLSIPGLWLYRKRPRV"
     gene            4561..5100
                     /gene="dnaT"
                     /locus_tag="RN951_003955"
     CDS             4561..5100
                     /gene="dnaT"
                     /locus_tag="RN951_003955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaT"
                     /protein_id="HDX2528882.1"
                     /translation="MSSRVLTPDVVGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYA
                     VTPARLAELLALEEKLARPGSDVALDDQLYQEPQAAPVAVPMGKFAMYPDWQPDADFI
                     RLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRASNGGLPK
                     RDVNTVSEPDSQIPPGFRG"
     gene            5103..5840
                     /gene="dnaC"
                     /locus_tag="RN951_003956"
     CDS             5103..5840
                     /gene="dnaC"
                     /locus_tag="RN951_003956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaC"
                     /protein_id="HDX2528883.1"
                     /translation="MKNVGDLMQRLQKMMPAHIKPAFKTGEELLAWQKEQGAIRSAAL
                     ERENRAMKMQRTFNRSGIRPLHQNCSFENYRVECEGQMNALSKARQYVEEFDGNIASF
                     IFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFRNSGTSEEQLLNDL
                     SNVDLLVIDEIGVQTESKYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMTKLLGERVM
                     DRMRLGNSLWVIFNWDSYRSRVTGKEY"
     gene            5889..6383
                     /locus_tag="RN951_003957"
     CDS             5889..6383
                     /locus_tag="RN951_003957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2501 domain-containing protein"
                     /protein_id="HDX2528884.1"
                     /translation="MMKTVKHLLCCAIAASALISTGVHAASWKDALSSAASELGNQNS
                     TTQEGGWSLASLTNLLSSGNQALSADNMNNAAGILQYCAKQKLASVTDAENIKNQVLE
                     KLGLNSEEQKEDTNYLDGIQGLLKTKDGQQLNLDNIGTTPLAEKVKTKACDLVLKQGL
                     NFIS"
     gene            6637..8928
                     /gene="opgB"
                     /locus_tag="RN951_003958"
     CDS             6637..8928
                     /gene="opgB"
                     /locus_tag="RN951_003958"
                     /EC_number="2.7.8.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418779.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerol--membrane-oligosaccharide
                     glycerophosphotransferase"
                     /protein_id="HDX2528885.1"
                     /translation="MSELLSFALFLASVLIYAWKAGRNTWWFAATLTVLGLFVVLNIT
                     LFASDYFTGDGINDAVLYTLTNSLTGAGVSKYILPGIGIVLGLTAVFGALGWILRRRR
                     HHPHHFGYSLLALLLALGSVDASPAFRQITELVKSQSRDGDPDFAAYYKEPSKTIPDP
                     KLNLVYIYGESLERTYFDNEAFPDLTPELGALKNEGLDFSHTQQLPGTDYTIAGMVAS
                     QCGIPLFAPFEGNASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKS
                     HGFDHLYGSEELKSVVADPHYRNDWGFYDDTVLDEAWKKFEELSRSGQRFSLFTLTVD
                     THHPDGFISRTCNRKKYDFDGKPNQSFSAVSCSQENIAAFINKIKASPWFKDTVIVVS
                     SDHLAMNNTAWKYLNKQDRNNLFFVIRGDKPQQETLAVKRNTMDNGATVLDILGGDNY
                     LGLGRSSLSGQSMSEIFLNIKEKTLAWKPDIIRLWKFPKEMKEFTIDQQKNMIAFSGS
                     HFRLPLLLRVSDKRVEPLPESEYSAPLRFQLADFAPRDNFVWVDRCYKMAQLWAPELA
                     LSTDWCVSQGQLGGQQIVQHIDKTTWQGKTAFKDTVIDMARYKGNVDTLKIVDNDIRY
                     KADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQLGDEVKIEYKHPLPKKFDLVITA
                     KAYGNNASRPIPVRVGNEEQTLVLGNEVTTTTLHFDNPTDADILVIVPPEPVSTNEGN
                     ILGHSPRKLGIGMVEIKVVEREG"
     gene            complement(9067..10089)
                     /gene="lgoD"
                     /locus_tag="RN951_003959"
     CDS             complement(9067..10089)
                     /gene="lgoD"
                     /locus_tag="RN951_003959"
                     /EC_number="1.1.1.414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418778.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-galactonate oxidoreductase"
                     /protein_id="HDX2528886.1"
                     /translation="MSTMNVLICQQPKELVWKQREIPIPGDNEALIKIKSVGICGTDI
                     HAWGGNQPFFSYPRVLGHEICGEIVGLGKNIADLKNGQQVAVIPYVACQQCPACKSGR
                     TNCCEKISVIGVHQDGGFSEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAI
                     APGEQVLVVGAGPIGLGAAAIAKADGAQVVVADTSPARREHVATRLELPLLDPSAEDF
                     DAQLRAQFGGSLAQKVIDATGNQHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHK
                     KETTMMGSRNATPEDFAKVGRLMAEGKITADMMLTHRYPFATLAETYERDVINNRELI
                     KGVITF"
BASE COUNT         2626 a         2616 c         2408 g         2532 t
ORIGIN      
        1 tatctttact tcctttcttg tttcttccct gttttgtcat ccctgattca aattcactat
       61 catcagcatg atgccagcaa taagcgccag gcacgatggt agcaaaatgt aatgccgcaa
      121 ctgtttgtga tacagcatca caggcgtcaa tactaatccc atcagaatga caatccgcca
      181 ctgatccggc gataaatccg catacatcag ccctgcaatc agcaatcccg gcagcaacac
      241 tccccagcca ctgcccagca tacgttgcaa catggtttca tctctttcat tgataatgat
      301 aaccaatatc atatgataat ttttatcatt tgcaagccag agaaatccct tgctatcggg
      361 taaacctatc gctaggatta gcaatcatta tcatttagat tactatcccg attatggcct
      421 atcgttccgc accgctctat gaagatatca tctggcgaac gcatctccag ccacaggatg
      481 ctgggcttgc acaagccgta cgtgcgacga tcgccgaaca tcgtgaacat ttgctggagt
      541 ttatccgtct ggatgaaccc gccccgcttc gcgccatgac gctggcgcaa tggtcatcac
      601 cgaatacgct aagttcccta ctggcggtct attccgatca tatctaccgc aaccaaccaa
      661 cgatgatccg cgagaacaag ccgctgatct cactgtgggc acaatggtat atcggcctga
      721 tggtgccacc attaatgctg gcgctgctga cgcaggaaaa agcattagat gtgacgccgg
      781 aacatttcca cgttgagttt cacgaaaccg gacgcgccgc ctgtttctgg gtcgatgtgt
      841 gtgaagataa aaacgcaaca ctacattcgc cgcagcagcg aatggaaacg ttaatcagcc
      901 aggcgcttgt tccggttgtg caggcactag aagcaacggg agagattaac ggtaaactta
      961 tctggagcaa taccggttat ttgatcaact ggtatctgac tgagatgaaa cagctgctcg
     1021 gcgaggcgac ggttgaatcg ctgcgccatg ccctcttttt tgagaaaacg ctcacgaacg
     1081 gtgaagataa tccactctgg cgtaccgtgg tgctgcgcga cggcctgctg gtgcgccgca
     1141 cttgctgcca gcgttatcgc ttaccggatg tgcagcaatg tggcgattgt acgctgaaat
     1201 gaaagcactg ccggggaagt aaacccggca tcatgcaaat taatagggat gcaacacatt
     1261 acttgcttcg caatgccgca tacataacag aatatctgcg gcctccaaca accctgcatc
     1321 agaactgacg cccagtttcg acatcacatt aaatttatgt gcacggatcg ttttgatatt
     1381 gcgtttaagc tgctcggcaa tttgtgtcat tgagtagcca cgcgacataa agcgcaatat
     1441 ttctctctcc gtcgggctta gcgtccggct ttggttaatg taccactgat tgttcagtcg
     1501 gtcggtcgcc tgacgtacac catttaatga caaaaagagt tcctgatgaa aaatctccag
     1561 cgttgacgct ttacttaata caccgtccag cggtgatggc gacaatgaac cgatcagccg
     1621 agcttcaata tcatcatccg caataactaa acgtcgggta cgcggaaact taatcgccag
     1681 ttcagtcagg caagataatc cctctctgcg ttcacttctc atggcagaaa aagaaaaaat
     1741 gaccgccgca aacgagatcc gcgacatggc atcctgaaat gactcctgac tggtataggt
     1801 atggagctta taagggttac ctgcaaactt tctgaataaa ctctcaatac cgatactgct
     1861 catgacgcat ttttctatga gtgcgacatt tctcttctta attcggctgt gttccattct
     1921 gcggcatctc cataaacaga aggcaagtta agttctcttg caccctgcgc gctatttatc
     1981 catgcataca tttcagcgtt gctgtgaatt gccagtcgac gcatcgcact gtttttttgg
     2041 gcgctgatag ttttattact tttcttaagc aatgaagcta tctggttgat gccccatcct
     2101 ttacctaata gccgcagtac cttgcgctct gaaagagtga gaatgacgga gcgatagcta
     2161 aaatcatgag tttcagtcat tgccggagag gtcagcatgg cgctgatacg ctctgcgtgc
     2221 gtattgccgg aacgtacggt cttgaccaga ttctcaatgg gttcaacatc agacaataac
     2281 gtcgccgtag ggcacatgag cagttctact gcctgggaat accaggagcg tgacaccatg
     2341 aaaacccagt gaatttcccg atattgtgag attaaagaat aataatgttc acaaacagaa
     2401 cgtggatctt cactttcacc ggctaaatca gcaatgacta atccggaacg acgtaattgt
     2461 aataaggtaa ggtcctccgc agaggcgctg gatattattt catattcagg gaagtgagtc
     2521 ctcatgacct cttttaaccc tgcttgcata acaggtattt tactgataac aattccattt
     2581 ttgcagcatc ctggcaacat atttcctcca catccactgt ctaaaaatca tgatggttta
     2641 ttcaggatat tcattcctta aatgtttcca gcaaattaat agattaagcg aataaattat
     2701 ccttagcatt cactttcata tcagcatact cctgctgcac aacaactcca cagcatgtgt
     2761 cagaaggtta gcatcaaatg ataacctggt gaaatagcct ggagacattt aaaatatcta
     2821 cattaagttg ttagaaatac ttaatgaaaa acagagttct cattcattta atttataatt
     2881 aactgatatc ccttcccgca gaatgcaaaa tcacacaatc aatatttgtt caataaaatc
     2941 tgatagtttt aacttgtaaa aattaaaaaa cgcgcccagt tatcttttat cctgattcgt
     3001 aaaggctaaa gaataaattc attatagtga taatattcat gtgataattt gtttgcggcg
     3061 agagataatt ccctttttat caccgagctt gtcccgataa ccaggattaa tcagcgcaat
     3121 tttgatctta acctaccgca aaactaccgt gcttcatgat acaaatggat tctcattatc
     3181 tgaacaatac gcagcacgtc tatgacaaag ggcgagttat gcaaactgag caacagcgag
     3241 ccgtaacacg gctttgtatc cagtgtggat tatttctttt gcaacatggt gcggaaagcg
     3301 cgttggttga tgagctttcc tcacgactgg gtcgggcgtt ggggatggac agcgtcgaaa
     3361 gttctatctc ttcgaacgcc atagtgctga caaccattaa agatgggcaa tgcctgacat
     3421 cgacacgtaa aaatcaagat cgcggcatta atatgcatgt ggtgactgaa gtccagcaca
     3481 ttgtgattct ggcggagcac catctgctgg attacaaagg cgtagagaaa cgatttagcc
     3541 aaattcagcc attacgttac ccaagatggc tggtagcctt aatggttggc ctttcctgcg
     3601 cctgtttctg taaactcaat aaaggtggct gggatggtgc cgtcatcacc ttctttgcca
     3661 gtacggccgc gatgtatatc cgccagctgc tggcacaacg tcatcttcat ccacagatca
     3721 acttttgcct taccgctttc gccgccacca ccatttccgg attgcttttg caactcccta
     3781 ctttcagcaa tacccccacc atcgcgatgg ccgccagcgt tctgctgctg gtgccgggct
     3841 ttccgttgat taatgccgtc gccgatatgt ttaaaggcca catcaatacc ggactggcac
     3901 gctgggcgat cgccagtctg ctgacactgg ctacctgcgt cggcgtggtg atggcactga
     3961 cgatttgggg gctacgcgga tgggtgtgat cgagtttctg tttacattgg cgcaggatat
     4021 gatcctcgcc gccattccag cggtcggctt tgcgatggtg ttcaacgttc ccgttcgggc
     4081 gttacgctgg tgtgcgctgc ttggcgcgat tggtcatggt tcacgaatga tcttaatgac
     4141 cagcgggctg aatattgagt ggtcaacttt tatggcttct atgctggtcg gcaccattgg
     4201 tattcaatgg tcgcgctggt atctggcgca tccgaaagtg tttaccgtgg cggccgttat
     4261 ccctatgttc cctggcatat cggcttatac cgcaatgatt tcggcggtaa aaatcagcca
     4321 gttaggttac agcgagtcat tgatgattac cctgttaacc aactttctta cagcttcatc
     4381 gattgttggt gcgttatcca tcggtctttc cattcctgga ttatggttgt accgcaagcg
     4441 ccctcgcgta taaaattgcc tcgcttaaag cacacggatg agagacagcc tcctctcctc
     4501 catgtgttac tataaaagtt atctcccttc tcgttcatcg ttccatattt gagaaacagt
     4561 atgtcttcca gagttttgac cccggacgtc gttggtattg acgccctggt acacgatcac
     4621 caaaccgttc tggcaaaagc tgaaggcggt gtggttgccg tatttgctaa caatgccccg
     4681 gcgttttatg ccgtcacgcc tgcacgcctg gctgaactgc tggcgctgga agaaaagctg
     4741 gcgcgtccgg gaagcgatgt cgctctggac gatcaactct atcaggaacc gcaagccgct
     4801 cccgttgctg tacccatggg gaaattcgcc atgtatccgg actggcaacc cgatgccgac
     4861 tttatccgcc tggcggcgct atggggcgtg gcgctaagag agccggtgac caccgaagaa
     4921 ctggcctcat tcattgccta ctggcaggcg gaaggtaaag tctttcacca tgtacagtgg
     4981 caacaaaaac tggcgcgcag cctgcaaatc ggccgtgcca gcaacggcgg actgccgaaa
     5041 cgagatgtga atacggtcag cgaacctgac agccaaattc caccaggatt cagagggtaa
     5101 cgatgaaaaa cgttggcgac ctgatgcaac gcctgcaaaa aatgatgcct gcccatatca
     5161 aacctgcgtt taaaacgggt gaagaactac tggcctggca gaaagaacaa ggggcgatcc
     5221 gctccgccgc tctcgaacgt gaaaatcggg cgatgaaaat gcagcgcacc tttaaccgct
     5281 ccggtattcg tccactgcat cagaactgct cctttgagaa ctatcgcgtt gagtgtgaag
     5341 ggcagatgaa tgcgttaagc aaagcgcgcc agtatgtcga agagtttgac ggcaacatcg
     5401 ccagcttcat cttttctggt aagccaggaa ccggcaaaaa ccatctggcg gcggcaatct
     5461 gcaacgagct gctgctacgc ggtaaatccg tattgatcat caccgtggcc gatattatgt
     5521 cggcgatgaa agataccttc aggaatagcg gtaccagcga agaacaactg cttaacgatc
     5581 tgagcaacgt tgatctgctg gtgatcgatg agatcggcgt gcagaccgaa tcgaaatacg
     5641 aaaaagtgat catcaaccag atcgtcgatc gccgctcttc ttccaaacgc ccaaccggga
     5701 tgctgaccaa cagtaatatg gaagagatga ccaagttgct gggcgaacgc gtgatggacc
     5761 gtatgcgcct gggtaacagt ttgtgggtga tcttcaactg ggatagctac cgtagccgtg
     5821 taacaggtaa agagtattaa tccccgtttc tggcggtata ctgcgacaca attccacctt
     5881 gagtaatgat gatgaaaact gttaaacatc ttctgtgctg tgccattgcc gccagcgcat
     5941 taatttccac cggggtgcat gctgcgtcct ggaaagatgc gctctccagc gccgccagcg
     6001 aacttggcaa ccaaaacagc acgacacagg aaggcggttg gtcgctcgcg tcattaacta
     6061 acttgcttag cagcgggaac caggccttaa gcgcagataa catgaacaac gccgcaggca
     6121 ttctgcaata ctgcgcgaag caaaagctgg cgtcggtaac cgatgccgaa aacatcaaga
     6181 accaggtgct ggaaaagctg ggcctgaaca gtgaagagca aaaagaagac accaactatc
     6241 tggatggcat tcagggtttg ctgaaaacca aagatggtca gcaactcaat ctggataaca
     6301 tcggaacgac tccgctggca gaaaaggtga aaaccaaagc ctgcgatctg gtgttaaagc
     6361 aggggctgaa cttcatttcc tgaaccgcga aacgccgcgt tttagctgtt acccggctga
     6421 cgcggctctc tcctgccctt ttccctgctc ctggacggtt ttccccctgt tacacgggaa
     6481 gcgaccgcga tcaaaaaagt ctgtttataa actaattcct aacaacatcg catttttttg
     6541 acactagaat tgcagcaata tggcgacgcc attacattgt gcttctcaaa aagcttaaac
     6601 gttggctaaa cggcccggtt tagtgaggat cgcccgttgt cagaactact ctctttcgcc
     6661 ctttttctcg cctctgtgct gatttacgca tggaaagcgg gacgtaacac ctggtggttt
     6721 gcagccacat taacggtgtt ggggctattt gtcgttttaa atatcaccct gtttgccagc
     6781 gactatttta ctggcgatgg tattaacgac gcggttctct ataccttaac caacagcctg
     6841 accggtgctg gcgtcagcaa atacatcctg ccgggtatcg gcattgtgct ggggctgaca
     6901 gcggtgttcg gtgcgctggg ctggatcctg cgccgtcgtc gccatcatcc gcaccatttt
     6961 ggttacagcc tgctggcgct cttactggcg ctgggttcgg tggacgccag cccggcattt
     7021 cgtcagataa cggaactggt gaaatcccag tcacgcgatg gcgacccgga ctttgcggct
     7081 tattataaag agccgtcgaa aactatccct gacccgaaac tcaacctggt ttatatctac
     7141 ggcgaaagtc tcgagcggac ctattttgat aacgaagctt tcccggatct cacgcctgaa
     7201 ctgggcgcgt tgaaaaatga aggcctggat ttcagccaca cgcagcagct gccaggaacg
     7261 gattacacga ttgcgggcat ggtggcttct cagtgcggca taccgctgtt tgcccccttt
     7321 gaaggcaacg cctccgcctc tgtctccagc ttcttcccgc agaacatctg tctgggcgat
     7381 atcctgaaaa actcgggtta tcagaactat ttcgtgcagg gcgcgaatct gcgttttgcc
     7441 ggtaaagatg tgttcctgaa gtcgcatggc ttcgaccact tatacggctc agaagagctg
     7501 aaaagcgtgg tggccgaccc gcactatcgc aacgactggg gattctacga cgataccgtt
     7561 ctcgatgaag cgtggaaaaa gtttgaagag ctttcccgct caggtcagcg attctcactg
     7621 tttaccctga cagtcgatac ccatcacccg gatggtttta tctcgcgtac ctgtaaccgc
     7681 aaaaaatatg attttgacgg taagccgaac cagtcattca gcgcggtaag ttgcagccag
     7741 gagaatatcg cggcgtttat caacaaaatc aaagcgtcac cgtggtttaa agataccgtc
     7801 atcgtcgtct cttctgacca tttagcgatg aacaacacgg cgtggaaata cctcaataag
     7861 caggatcgca ataacctgtt ttttgtcatt cgtggcgaca agccgcagca agagacgctg
     7921 gcagtgaagc gtaacacgat ggataacggc gcgacggtgc tggacattct cggtggcgat
     7981 aactatctcg gacttggtcg tagcagttta tccgggcagt caatgtcgga aatcttcctc
     8041 aatatcaaag agaaaacatt ggcgtggaag ccggatatca tccgcctgtg gaaattccct
     8101 aaagagatga aagagttcac catcgaccag cagaaaaaca tgattgcctt ctcgggtagc
     8161 catttccgtt tgccgctgct gttgcgggtt tcagacaaac gcgtggaacc gctgccggaa
     8221 agcgaatact cagcaccgct gcgtttccag ctggccgatt tcgctccacg cgacaatttc
     8281 gtctgggttg accgttgcta taagatggca caactctggg ctccggaact ggcactctcc
     8341 accgactggt gtgtctcgca agggcagctt ggcggtcagc aaattgttca gcatattgac
     8401 aaaacaacat ggcagggcaa aacggcattt aaagatacgg tcatcgacat ggcgcgttat
     8461 aaaggcaatg tcgatacgct gaaaattgtt gataacgata ttcgctacaa agccgacagt
     8521 ttcatcttca acgtcgccgg tgcgccagaa gaggtgaaac agtttagtgg gatttcccgt
     8581 ccagagtcgt ggggccgctg gtccaacgcg cagctgggcg atgaagtaaa aatcgagtac
     8641 aagcatccgc tgccaaagaa atttgacctg gtgattaccg ccaaagcata cggcaataac
     8701 gccagccgtc ctattccggt acgcgtaggc aatgaagaac aaacccttgt gctgggcaat
     8761 gaagtgacca ccaccacact gcatttcgat aacccaaccg atgccgacat actggtaatt
     8821 gtgccgccgg aacctgtctc aaccaacgaa gggaatatcc tcggacactc gccgcgtaag
     8881 ctcgggatcg gcatggtgga aattaaagtg gtggaacgtg aaggataatt cctgactgat
     8941 gtgtaggtcg cataaggtgc gacctacaca ccttctgcgg cctacaaaac atcattgaga
     9001 aacagaaaaa aacagcgccc aacacttccc cggacgctgc atggcaactt taataatctc
     9061 gccttatcag aaagtaatta cacccttaat caactcacga ttgttaatca catcgcgctc
     9121 gtaggtttct gccagcgtgg cgaacggata gcgatgggtt aacatcatgt cagcagtgat
     9181 ttttccttcc gccatcagtc gaccgacttt agcaaaatct tccggcgtgg cgttgcggct
     9241 acccatcatc gtcgtttctt ttttatggaa ttccggatcg gagaactgca actcaccttt
     9301 aaacaggccg acaaatacca ccgtgccgcc gtgacgaatc aaattcacgg tgttattcat
     9361 cgcatgttga ttacctgtcg cgtcgatcac tttctgcgcc agcgaaccac caaactgcgc
     9421 ccgtagctgc gcgtcaaaat cttcggctga cgggtccagt aaaggtaatt ccagacgcgt
     9481 tgccacatgt tcacggcgcg ccggactggt atccgccacc accacctgtg cgccatcggc
     9541 tttagcgatt gccgccgcgc ccagaccgat tggccccgcc ccgaccacca gcacctgctc
     9601 gccgggagca atggctgcgc gacgcaccgc atgagcgcta atagcgaaag gttcaatcaa
     9661 tgctgccgcc tgcgggtcaa taccgtctgc gggcaaaatg ttcgccaccg gcacgctcaa
     9721 atactcacta aaaccgccat cctgatgcac gccaatgact gaaatttttt cacagcaatt
     9781 ggtacgcccg cttttacacg ccgggcattg ctgacaggca acataaggga tcacagcaac
     9841 ttgctgacca tttttaagat cagcaatatt tttacccaac ccaacaatct ccccacatat
     9901 ttcatggcct aaaacacgtg gataactaaa aaatggttga tttccacccc aggcatgaat
     9961 atcggtaccg caaatcccga cagacttaat ttttattaat gcttcattgt cacccggaat
    10021 aggtatctcg cgttgtttcc agactaattc tttcggctgc tggcaaatta aaacattcat
    10081 cgtagacatg attcggctct ccattttttg ttgccttaga tatcaatgaa aatgaaaaat
    10141 ggcagcggaa cggaaaatct gttttgtgaa aacacacgca ta
//
LOCUS       DAPOAV010000124        10120 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.124, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000124 DAPOAV010000000
VERSION     DAPOAV010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10120
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.124"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            169..672
                     /locus_tag="RN951_003960"
     CDS             169..672
                     /locus_tag="RN951_003960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin-like protein"
                     /protein_id="HDX2528887.1"
                     /translation="MATAGMLLKLNSQMNREFYASNLYLHLSNWCSEQSLNGTATFLR
                     AQAQSNVTQMMRMFNFMKSVGATPIVKAIDVPGEKLNSLEELFQKTMEEYEQRSSTLA
                     QLADEAKELNDDSTVNFLRDLEKEQQHDGLLLQTILDEVRSAKLAGMCPVQTDQHVLN
                     VVSHQLH"
     gene            complement(751..1002)
                     /locus_tag="RN951_003961"
     CDS             complement(751..1002)
                     /locus_tag="RN951_003961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416416.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2766 domain-containing protein"
                     /protein_id="HDX2528888.1"
                     /translation="MSQPLNADQELVSDVVACQLVIKQILDVLDVIAPVEVREKMSSQ
                     LKNIDFTNHPAAADPVTMRAIQKAIALIELKFTPQGESH"
     gene            complement(1117..1203)
                     /gene="azuC"
                     /locus_tag="RN951_003962"
     CDS             complement(1117..1203)
                     /gene="azuC"
                     /locus_tag="RN951_003962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein AzuC"
                     /protein_id="HDX2528889.1"
                     /translation="MKLRKILKSMFNNYCKTFKDVPPGNMFR"
     gene            1466..1789
                     /locus_tag="RN951_003963"
     CDS             1466..1789
                     /locus_tag="RN951_003963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecR-like lipofamily protein"
                     /protein_id="HDX2528890.1"
                     /translation="MRLLILTLSLITLAGCTVTRQAHVSEVDAATGIVRLVYDQAFLQ
                     HAHTDRYVSRGIADRACQQEGYTHAVPFGQPVGNCSLFAGSLCLNTEFTLSYQCHHSA
                     FPVFL"
     gene            1960..2457
                     /gene="ftnA"
                     /locus_tag="RN951_003964"
     CDS             1960..2457
                     /gene="ftnA"
                     /locus_tag="RN951_003964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin"
                     /protein_id="HDX2528891.1"
                     /translation="MLKPEMIEKLNEQMNLELYSSLLYQQMSAWCSYHTFEGAAAFLR
                     RHAQEEMTHMQRLFDYLTDTGNLPRINTVESPFAEYSSLDELFQETYKHEQLITQKIN
                     ELAHAAMTNQDYPTFNFLQWYVSEQHEEEKLFKSIIDKLSLAGKSGEGLYFIDKELST
                     LDTQN"
     gene            complement(2495..2734)
                     /locus_tag="RN951_003965"
     CDS             complement(2495..2734)
                     /locus_tag="RN951_003965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecH family protein"
                     /protein_id="HDX2528892.1"
                     /translation="MDSIHGHEVLNMMIESGEQYTHASLEAAIKARFGEQARFHTCSA
                     EGMTAGELVAFLAAKGKFIPSKDGFSTDQSKICRH"
     gene            2925..4136
                     /gene="tyrP"
                     /locus_tag="RN951_003966"
     CDS             2925..4136
                     /gene="tyrP"
                     /locus_tag="RN951_003966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine transporter TyrP"
                     /protein_id="HDX2528893.1"
                     /translation="MKNRTLGSVFIVAGTTIGAGMLAMPLAAAGVGFSVTLILLIGLW
                     ALMCYTALLLLEVYQHVPADTGLGTLAKRYLGRYGQWLTGFSMMFLMYALTAAYISGA
                     GELLASSISDWTGISMSATAGVLLFTFVAGGVVCVGTSLVDLFNRFLFSAKIIFLVVM
                     LVLLLPHIHKVNLLTLPLQQGLALSAIPVIFTSFGFHGSVPSIVSYMDGNIRKLRWVF
                     IIGSAIPLVAYIFWQVATLGSIDSTTFMGLLANHAGLNGLLQALREMVASPHVELAVH
                     LFADLALATSFLGVALGLFDYLADLFQRSNTVGGRLQTGAITFLPPLAFALFYPRGFV
                     MALGYAGVALAVLALIIPSLLTWQSRKHNPQAGYRVKGGRPALVVVFLCGIAVIGVQF
                     LIAAGLLPEVG"
     gene            complement(4198..4863)
                     /gene="yecA"
                     /locus_tag="RN951_003967"
     CDS             complement(4198..4863)
                     /gene="yecA"
                     /locus_tag="RN951_003967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0149 family protein YecA"
                     /protein_id="HDX2528894.1"
                     /translation="MKTGPLNESELEWLDDILTKYNTDHAILDVAELDGLLTAVLSSP
                     QEIEPEQWLVAVWGGADYVPRWASEKEMTRFMNLAFQHMADTAERLNEFPEQFEPLFG
                     LREVDGSELTIVEEWCFGYMRGVALSDWSTLPDSLKPALEAIALHGTEENFERVEKMS
                     PEAFEESVDAIRLAALDLHAYWMAHPQEKAVQQPIKAEEKPGRNDPCPCGSGKKFKQC
                     CLH"
     gene            complement(5059..5145)
                     /locus_tag="RN951_003968"
     tRNA            complement(5059..5145)
                     /locus_tag="RN951_003968"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5109..5111),aa:Leu,seq:taa)
     gene            complement(5158..5231)
                     /locus_tag="RN951_003969"
     tRNA            complement(5158..5231)
                     /locus_tag="RN951_003969"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5197..5199),aa:Cys,seq:gca)
     gene            complement(5285..5360)
                     /locus_tag="RN951_003970"
     tRNA            complement(5285..5360)
                     /locus_tag="RN951_003970"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5325..5327),aa:Gly,seq:gcc)
     gene            complement(5512..6060)
                     /gene="pgsA"
                     /locus_tag="RN951_003971"
     CDS             complement(5512..6060)
                     /gene="pgsA"
                     /locus_tag="RN951_003971"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HDX2528895.1"
                     /translation="MQFNIPTLLTLFRVILIPFFVLVFYLPVTWSPFAAALIFCVAAV
                     TDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIAMVLVTEHYHSWWVTLPAATMIARE
                     IIISALREWMAELGKRSSVAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVA
                     AVLTLWSMLQYLSAARADLLDQ"
     gene            complement(6117..7949)
                     /gene="uvrC"
                     /locus_tag="RN951_003972"
     CDS             complement(6117..7949)
                     /gene="uvrC"
                     /locus_tag="RN951_003972"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310678.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HDX2528896.1"
                     /translation="MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLS
                     SYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSY
                     PFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
                     NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETAS
                     QNLEFEEAARIRDQIQAVRRVTEKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKV
                     LGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLS
                     ELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEV
                     KRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRY
                     GKAIDDSKIPDVILIDGGKGQLAQAKNVFAELDVSWDKNHPLLLGVAKGADRKAGLET
                     LFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLETIEGVGP
                     KRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH"
     gene            complement(7946..8602)
                     /gene="uvrY"
                     /locus_tag="RN951_003973"
     CDS             complement(7946..8602)
                     /gene="uvrY"
                     /locus_tag="RN951_003973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrY/SirA/GacA family response regulator
                     transcription factor"
                     /protein_id="HDX2528897.1"
                     /translation="MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCR
                     ANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIMLTVHTENPLPAKVMQAGAAGYL
                     SKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
                     ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ
                     "
     gene            8898..9074
                     /locus_tag="RN951_003974"
     CDS             8898..9074
                     /locus_tag="RN951_003974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528898.1"
                     /translation="MIKIFIGHYINAFNSTVDDTLKKQPLLFLAKLMVYSAALTFFTA
                     NFHCNMTRKINEYA"
     gene            9061..9285
                     /locus_tag="RN951_003975"
     CDS             9061..9285
                     /locus_tag="RN951_003975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2594 family protein"
                     /protein_id="HDX2528899.1"
                     /translation="MSTPDFSTAENNQELANEVSCLKAMLTLMLQAMGQADAGRVMLK
                     MEKQLALIEDETQAAVFSKTVKQIKQAYRQ"
     gene            complement(9353..10075)
                     /gene="sdiA"
                     /locus_tag="RN951_003976"
     CDS             complement(9353..10075)
                     /gene="sdiA"
                     /locus_tag="RN951_003976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SdiA"
                     /protein_id="HDX2528900.1"
                     /translation="MQDTDFFSWRRTMLLRFQRMEAAEEVYHEIEFQAQQLEYDYYSL
                     CVRHPVPFTRPKVAFYTNYPEAWVSYYQAKNFLAIDPVLNPENFSQGHLMWNDDLFSE
                     AQPLWEAARAHGLRRGVTQYLMLPNRALGFLSFSRSSAREIPILSDELQLKMQLLVRE
                     SLMALMRLNDEIVMTPEMNFSKREKEILKWTAEGKTSAEIAMILSISENTVNFHQKNM
                     QKKINAPNKTQVACYAAATGLI"
BASE COUNT         2544 a         2551 c         2330 g         2695 t
ORIGIN      
        1 aagcattttc ttatacccgt tcagacgtta ttcttatttc agatcatcgt cagaattgac
       61 tccacgatca catttcggac cggcagaaag gaattattct gcaaacagta attatggtgt
      121 tttgatttat cttgcacctc tccacttctg gatataagga tattaggtat ggcaaccgct
      181 ggaatgcttc tcaaactcaa ctctcaaatg aaccgcgagt tttacgcatc caatctctac
      241 cttcacctga gtaactggtg ttctgaacag agtctgaacg gcaccgccac tttccttcgc
      301 gcccaggcac agagtaatgt gacccaaatg atgcgcatgt ttaactttat gaagagtgtc
      361 ggcgctaccc ccatcgttaa agccattgat gttcccggtg aaaaactgaa ctctctggaa
      421 gaactgttcc aaaaaacgat ggaagaatac gagcaacgtt ctagtacgtt ggcacagtta
      481 gccgatgaag cgaaagaact gaatgatgat tcaaccgtca atttcctgcg cgatctggaa
      541 aaagaacagc agcatgatgg tctgttgctg caaaccattc ttgatgaagt gcgcagtgcg
      601 aaacttgcgg gtatgtgccc tgtgcagacc gaccaacatg ttctgaatgt cgtgtcacac
      661 cagctgcatt gatcatcatc ggcgctaatg cattgcgccg atgaaggttt tgagaaaccg
      721 ctgcctcatc tgtttgaagc agcggttttt ttaatgggat tcaccctgtg gggtaaactt
      781 gagttcaata agcgcgatgg ctttttggat tgcccgcatg gtgaccgggt ctgcggcggc
      841 gggatggtta gtaaagtcga tattcttcag ctgactggac attttttcac gaacttcaac
      901 gggcgcgatt acatcgagaa catccagaat ttgtttgata accaactggc aagcaaccac
      961 atcagaaacc aattcctgat cggcattcag cggctgggac atcgtaaact cctgatagca
     1021 ttttgaaagc cgttatagta gcgacttcac atcttcagcg atagtcacat ccaccgtcat
     1081 caggacacaa aaaaacctgc cggagcaggt tttttgttat cggaacatat tgcctggcgg
     1141 tacgtctttg aacgtcttgc aatagttatt gaacatactt ttcaggattt tgcgcagttt
     1201 catcgcggca ctccgaccat ttgttataca ggtgttattg tctttgcgct tataatatga
     1261 caaccatcac aaaaatcaat ctttatgtga tacaaatcac ataaataccc ctttaatgtt
     1321 ataaaaatga taatcaaaaa acagcccccc tatttctgac acctacagat ggcaagaaat
     1381 agcgcctgcc aggcgtcttt tccggccatt gtcgcagcac tgtaacgcgt aaaatagtgc
     1441 tttctcttac tcttctggct ggaccatgag acttctgatt ctgactcttt cattaataac
     1501 gctggcgggg tgtacggtta ctcgccaagc ccatgtgagc gaagttgacg cggcaacagg
     1561 tattgtacgg ttagtttatg accaggcttt tttgcagcat gcccataccg atcgttatgt
     1621 cagtcgcggg atcgccgatc gcgcatgcca gcaggaaggc tatacccacg cggtcccctt
     1681 tggtcagcca gtaggcaact gtagcctttt tgcgggttcc ttatgtttga atacggaatt
     1741 cactttgtca tatcagtgcc atcattccgc cttccctgtc tttctctaaa tattttaatc
     1801 agcgagggga tcttcgctga ttaaagaaat agcggtaatg cgttttattc ccattcgtat
     1861 ttttaataat tgaagtttat attttacctt ttgcaaataa taaaataaca aattatagtg
     1921 acgccacagc aacaaatata acctttgtgg agcactatca tgctgaaacc agaaatgatt
     1981 gaaaaactta atgagcagat gaacctggaa ctgtactctt cactgcttta tcagcaaatg
     2041 agcgcctggt gcagctatca taccttcgaa ggtgctgccg cgttcctgcg ccgtcacgcc
     2101 caggaagaga tgacgcatat gcagcgtctg tttgattacc tgactgatac cggcaattta
     2161 ccgcgtatta ataccgttga atctccgttt gctgaatatt cctcacttga tgaattattc
     2221 caggaaacct ataaacacga acaattaatc acccagaaaa ttaacgaact ggctcatgct
     2281 gcaatgacca atcaggacta cccaacattt aatttcctgc aatggtatgt ttctgagcag
     2341 catgaagaag agaaactgtt caaatcgatt attgataaat taagcctggc aggcaaaagc
     2401 ggcgaaggtc tgtattttat cgacaaagaa ctctctaccc tcgacacaca aaactaatgc
     2461 tctccggcgg caggtttact gccgccgttt caaatcagtg acggcaaatc ttactctgat
     2521 cggtcgaaaa accgtctttc gaaggtataa atttgccttt tgctgccaga aacgctacca
     2581 gctctcccgc tgtcatccct tctgccgagc aggtgtgaaa acgtgcctgt tcaccaaaac
     2641 gcgctttaat cgcagcttcc agactggcat gcgtatattg ctcgcctgat tcaatcatca
     2701 tatttaacac ttcatgaccg tgaatagagt ccatcgtccc tcctcaaaaa aagcctagcg
     2761 tagcgattgc cgcttatgaa gactttgcgc cagcgcagga ctgaatgctt tttattgtac
     2821 atttatattt acaccatatg taacgtcggt ttgacgaagc agccgttatg ccttaacctg
     2881 cgccgcagat atcactcata aagatcgtca ggacagaaga aagcgtgaaa aacagaaccc
     2941 tgggaagtgt ttttatcgtg gcgggaacca caattggcgc aggcatgctg gcaatgccgc
     3001 tggctgcggc cggtgttggt tttagcgtta cgttaatctt gttgattggg ctttgggcgt
     3061 tgatgtgcta cacggcgcta ttactgctgg aggtgtacca gcatgttccg gcagataccg
     3121 gtctgggcac gctggcaaaa cgctatctgg gacgctacgg tcaatggctg acgggcttca
     3181 gtatgatgtt cttaatgtat gctctgactg cggcatacat cagcggtgcc ggtgaattgt
     3241 tggcctccag catcagcgac tggacaggta tttctatgtc ggcaaccgct ggcgtgctgt
     3301 tgttcacttt tgttgccggt ggcgtggttt gtgtcggaac ttcactggtc gatttattta
     3361 accgttttct gttcagcgcc aagattattt ttctggtggt aatgctggta ctactgctgc
     3421 cgcatattca caaagtgaat cttttaaccc tgccgttgca acaggggctg gctctgtctg
     3481 caatcccggt gatttttacg tcgtttggtt ttcacggtag cgtgccgagt attgtcagct
     3541 atatggatgg caacattcgt aagctacgct gggtgtttat aatcggtagt gcgatccccc
     3601 tggtggcata tattttctgg caggtggcga cgcttggcag cattgattca acaaccttta
     3661 tgggattgct ggctaatcat gctggattaa acgggctgtt acaggcgtta cgcgaaatgg
     3721 tggcctctcc gcatgttgag ctggcagtgc atttatttgc tgatttagcc ctcgccacgt
     3781 catttctcgg cgttgcgtta ggcttatttg attatctggc tgatttattt cagcgttcaa
     3841 ataccgttgg tggacggttg caaactggtg caattacctt tctgccgccg ttggcgtttg
     3901 cactgtttta tccacgagga tttgtgatgg cgctgggtta cgccggtgtg gcgctggcgg
     3961 tactggcatt gattatccct tcgctgttga cctggcaaag cagaaagcac aatcctcagg
     4021 cgggttaccg ggtgaaaggt ggtcgtccgg cgctggtggt ggtgtttctc tgtggtattg
     4081 ctgtgattgg cgtgcaattt ttgattgcgg cagggttgtt accagaagtg gggtgatcag
     4141 atagcctcaa attccttatt gggtgccaga attaacgctg acacccaatt tgacctctta
     4201 atgcaggcag cactgcttaa atttcttacc actaccgcac gggcaaggat cgttacgccc
     4261 cggtttctct tctgctttga tcggttgctg aacagctttt tcctgcggat gcgccatcca
     4321 gtacgcatgt agatcaagcg ccgccagtcg aatggcatct acgctctctt caaacgcttc
     4381 tggcgacatc ttctctaccc gctcgaagtt ttcctcagta ccgtgcagcg caatcgcctc
     4441 cagcgctggt tttaacgaat cgggcaacgt tgaccagtca gaaagtgcca cgccccgcat
     4501 atagccaaag caccactcct caacaatcgt cagctcgctg ccatcgactt ctcgcaagcc
     4561 gaataacggc tcaaactgct ccgggaattc gttcagacgc tctgcggtat cggccatatg
     4621 ttgaaaggcc aggttcataa agcgcgtcat ctctttctct gacgcccagc gcggcacata
     4681 gtcagcccca ccccacacgg caaccagcca ctgttccggt tcaatctctt gcggagaact
     4741 caacaccgcc gtcaataaac cgtccagctc cgccacatca aggatggcgt ggtcagtgtt
     4801 gtatttggtc agaatatcgt ccagccattc caactcactt tcgtttaacg gtcccgtttt
     4861 catacgcttt tccttgtgga tctcaactcg ccagcaccta tcttacatgc cggtccgtat
     4921 cagagatact ttttgagtgg ctttgccggt gattaaaaat taaggagggt gtaacgacaa
     4981 gttgcaggca caaaaaaacc acccgaaggt ggtttcacga cactgcttat tgctttgatt
     5041 ttattcttat ctttcccatg gtacccggag cgggacttga acccgcacag cgcgaacgcc
     5101 gagggatttt aaatcccttg tgtctaccga ttccaccatc cgggctcggg aagaaagtgg
     5161 aggcgcgttc cggagtcgaa ccggactaga cggatttgca atccgctaca taaccgcttt
     5221 gttaacgcgc caaactcttc aggcctttca gccagacatc cgctgacgcc gatgtctttt
     5281 aaactggagc gggaaacgag actcgaactc gcgaccccga ccttggcaag gtcgtgctct
     5341 accaactgag ctattcccgc attcatcaag caatcagtta atcacttgat tttattatcg
     5401 tctggcaatc agtgccgccg ttcgatgcgt tgcattctac ttacctggcg cgatgagtca
     5461 acgatatttt tcaccacttt tgatcgtttg ctgaaaattg cgccgaaacg atcactgatc
     5521 aagcaaatct gcacgcgcag cgctcaaata ttgcaacatt gaccacagag tcagtaccgc
     5581 agccacaaag aaaagtgcaa taccggcgta ctcaacccaa atgttcggac gccacagcag
     5641 ccaagccaat gccaccatct gggcagttgt tttcactttc ccaatccagg agacagccac
     5701 gctactgcgt ttacccaact ccgccatcca ttcgcgtagc gcagaaataa taatttcacg
     5761 ggcgatcatc gttgctgccg gtaaggtcac ccaccagctg tgataatgct cggttaccag
     5821 caccatggcg atagccacga gaactttatc tgctacaggg tcaaggaaag caccaaaccg
     5881 ggtactctgg ttccagcggc gtgccagaaa accatcgaac cagtcagtca ccgccgcgac
     5941 gcagaaaatg agcgcggcgg caaacggcga ccaggtgaca ggcaaataaa agaccaatac
     6001 aaagaatggg ataaggatga cacggaacag tgtaagcaac gtagggatat taaattgcat
     6061 aatgacgggt aactatctgt tgtcagtgag attaccccta tgttgctaca gagacatcaa
     6121 tgtttcaacg accagaagat cttttctgcc agaccttgcg aaatacccgg cacttttgca
     6181 atttcctcga cgctggcgtt acgtaaacct tgcaaaccgc ccatatattt caacaacatt
     6241 tgccgacgtt ttggccctac gccttcaatg gtttccaggg aactggtatt tttgaccttc
     6301 gcccgttttt tgcggtgccc gccaatcgcg tgatcgtgtg attcgtcgcg aatatgctgg
     6361 ataacatgca gcgcgggaga atctggcggc aaactgaatc cctcaccttc cggctcaaag
     6421 aacagcgttt ccagcccagc cttacgatct gcacctttgg caacgccaag tagcagcgga
     6481 tgatttttat cccatgagac atccagttcg gcgaagacat ttttcgcctg cgcaagctgg
     6541 cctttgccgc cgtcgataag gatcacatcc gggatcttac tgtcgtcaat ggctttacca
     6601 taacgccgac gcagcacctg attcatcgcc gcataatcat cgcccggcgt gatgccagta
     6661 atgttatagc gccgatactc cgcacgcagc gggccgttag catcaaacac cacacaggag
     6721 gcgacggttt gttcacccat ggtatggctg atgtcaaagc actccatccg cttcacttcc
     6781 ggtaatttca acacgctggc aagcgcggtc agtcgctggt gaacggtaga ttgctgcgaa
     6841 agtttgctgg ttaaggccgt cgccgcattg gtgcgcgcga gtttcagata acgcgcccga
     6901 tcgccgcgag gtttggtttg aacattaatc ttgcgtcccg ccagttctga aagggaatcg
     6961 gcaagcagcg ttttatcgct aagattaaaa tcgagcagga tctcacccgg taaggtgcgc
     7021 atctggctgc cttgtaaata gaactgacct acgaaggttt ccaccacctc gctcagttcc
     7081 gtaccgccag gcactttcgg gaaatagctg cggctgccga gcactttacc ctgacgaatg
     7141 aacaatacgt ggacacaagc catgcccgca tcgaacgcca caccaataac gtcaaggtcg
     7201 tcgccggtat tggacacaaa ctgtttttcg gtgacgcgtc gcaccgcctg aatttggtcg
     7261 cgaatacgtg ccgcttcttc aaactccaga ttctggctgg cagtttccat acggctaatg
     7321 agttgcgtaa gcacctgatc atctttgcca gacaaaaaca ggcgcacata ctcgacctgc
     7381 tgagcgtatt cttcttcact caccagtcct tcaacgcacg gccccagaca gcgccctatc
     7441 tgatattgca gacacggacg cgagcgattg cgataaacac tattttcgca ctggcgaatg
     7501 gggaatatct tttgcagtaa cgccagtgtt tcacgtacgg catagccatt cgggaacggg
     7561 ccgaaatatt cacctttggc atgcttcgca ccacgatgca tcgccagacg cgggtgggta
     7621 tcgccactca ggaagataaa aggataagat ttatcatcgc gtagcaaaac gttgtaacgc
     7681 ggctgataga gtttgatgta gttgtgttcc agcaacagcg cttcggtttc tgtatgagta
     7741 accgttacat caatttgctg gatctgggcg accagcgctt cggttttgcg cgaagcgagg
     7801 ttgctacgga aatagctgga aagccgtttt ttcaggtctt tcgctttgcc gacatagata
     7861 accgtaccac cagcatcgta catgcgataa acgcctggct ggctggttac ggtttttaaa
     7921 aacgcttttg cgtcaaactg atcactcact gacttgataa tgtctccgca ttacacagac
     7981 catggcgaat tgccaggtga gtcagctcaa catcgccatg aatgtttagt ttactgaaca
     8041 tacgatagcg gtagctgttc accgttttcg gactgagatt gagctgttct gagatctcat
     8101 tgaccttctg gcccttggtg atcatcagca taatctgcaa ttcacgttca gacaaactgg
     8161 caaatgggct ttctgttttt tctggttcga tctggcttaa cgccatttgt tgagcgatgt
     8221 cagaagcaat gtaacgctgc cctgaataga cagaacgaat cgcactcacg acttcctgcg
     8281 gagccgcgcc tttgctgagg tagcccgcag caccggcctg catgactttc gctggtaaag
     8341 ggttttctgt atggacggta agcatgatga ttttgacatc agctgtggaa cgcgcgattt
     8401 tacgcgtcgc ctcaagaccg ccaatgcccg gcatactcat gtccattagc accacgtcaa
     8461 cggcatttgc ccgacaccac ttaacggcgt cttcaccgca cgatgcctca ccgacgactt
     8521 ttataccctt tatatcttcc agaatgcgtc gtatccctgc gcgcaccagt tcgtggtcat
     8581 caacaagtag aacgttgatc aaaggaatat ctccagaaat agggataacg ctactgatag
     8641 ttagtcattc gtatattagc ggtttttatt gcaactttga aacgttaaaa atggtgggta
     8701 ttcgattttt ctctcgtttt tgtcaattcg attgtccata gttatggtca cgcccgtcac
     8761 caacggctta ccggatcgtt tcacagtaag ccctgcgacg aaatgtgaca aaaattacct
     8821 ttattcagca aaaatgaaaa tcagcccgct gaatatgtaa cattaattaa cccgaacaat
     8881 acgggcaaaa aacattcatg ataaaaatat ttattggtca ttatattaac gcatttaata
     8941 gcaccgttga cgatacgctc aaaaaacaac cactgctatt tttagcaaag cttatggtat
     9001 actccgccgc cttaacattt ttcaccgcaa attttcattg caacatgacg aggaaaataa
     9061 atgagtacgc ctgatttttc tactgccgag aataatcaag aactggcaaa tgaagtctcc
     9121 tgcctgaaag cgatgctgac gctgatgctg caggcgatgg gacaagctga cgcgggccgc
     9181 gtgatgttaa agatggaaaa acagcttgcg ctgatcgaag acgaaaccca ggctgcagta
     9241 ttttccaaaa cggttaagca aattaaacaa gcctaccgtc agtaatataa aaccggctga
     9301 tagcgtgcct ttcagccggt ttttgcatct ggcacgcagg acagaaaaga gatcaaatta
     9361 agccagtagc ggccgcgtaa caggcaacct gggtcttatt tggtgcattg atttttttct
     9421 gcatgttttt ctgatggaaa ttgaccgtat tctcagagat tgacaaaatc atcgctatct
     9481 ctgctgatgt cttcccttcc gccgtccatt tcaaaatttc tttttcgcgc ttgctgaaat
     9541 tcatctctgg cgtcatcact atttcatcat ttaaacgcat cagagccatc agactttcgc
     9601 gcaccagtaa ctgcattttt aattgcagtt catcactaag aatgggtatt tcgcgcgcgc
     9661 tgctacggga aaaggacaaa aagcccagcg cccggtttgg cagcattaaa tactgagtga
     9721 caccgcggcg taaaccatgt gcgcgcgcgg cttcccataa cggctgtgct tcgctgaata
     9781 agtcatcatt ccacattaaa tggccctgac taaagttttc agggttcagc accggatcaa
     9841 ttgcgagaaa gttttttgcc tgataataac taacccacgc ctcagggtaa ttggtgtaga
     9901 aagccacttt aggtcgcgtg aatggtaccg ggtggcgaac acataacgaa tagtaatcgt
     9961 actccagctg ctgagcctga aactctattt catggtagac ctcttctgcg gcctccatcc
    10021 tctgaaaacg caacagcatc gtgcgacgcc agctgaaaaa atccgtatcc tgcatagtaa
    10081 accgcaacgc ccctgagagt gagtatcatt tataatgata
//
LOCUS       DAPOAV010000125         9953 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.125, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000125 DAPOAV010000000
VERSION     DAPOAV010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9953
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.125"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..307)
                     /locus_tag="RN951_003977"
     CDS             complement(<1..307)
                     /locus_tag="RN951_003977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047234906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDX2528901.1"
                     /translation="MRRTFTAEEKASVFELWKNGTGFSEIANILGSKPGTIFTMLRDT
                     GGIKPHERKRAVAHLTLSEREEIRAGLSAKMSIRAIATALNRSPSTISREVQRNRGRR
                     "
     gene            372..1276
                     /locus_tag="RN951_003978"
                     /pseudo
     CDS             372..1276
                     /locus_tag="RN951_003978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611482.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1359..1616
                     /locus_tag="RN951_003979"
     CDS             1359..1616
                     /locus_tag="RN951_003979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000177060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528902.1"
                     /translation="MTLVNDTGFDPVFSGSIAESWRQQPCTPSYCCDWEAATMLRAFP
                     LAKKGEGRARLPSLYASFGKLGETPTHEDIIDNNRSINWPV"
     gene            complement(2173..2940)
                     /gene="fecE"
                     /locus_tag="RN951_003980"
     CDS             complement(2173..2940)
                     /gene="fecE"
                     /locus_tag="RN951_003980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter ATP-binding
                     protein FecE"
                     /protein_id="HDX2528903.1"
                     /translation="MTLRTENLTVSYGTDKVLNDVSLSLPTGKITALIGPNGCGKSTL
                     LNCFSRLLMPQSGTVFLGDNPINMLSSRQLARRLSLLPQHHLTPEGITVQELVSYGRN
                     PWLSLWGRLSAEDNARVNVAMNQTRINHLAVRRLTELSGGQRQRAFLAMVLAQNTPVV
                     LLDEPTTYLDINHQVDLMRLMGELRTQGKTVVAVLHDLNQASRYCDQLVVMANGHVMA
                     QGTPEEVMTPGLLRTVFSVEAEIHPEPVSGRPMCLMR"
     gene            complement(2941..3897)
                     /gene="fecD"
                     /locus_tag="RN951_003981"
     CDS             complement(2941..3897)
                     /gene="fecD"
                     /locus_tag="RN951_003981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter permease
                     subunit FecD"
                     /protein_id="HDX2528904.1"
                     /translation="MKIALVIFITLALAGCALLSLHMGVIPVPWRALLTDWQAGREHY
                     YVLMEYRLPRLLLALFVGAALAVAGVLIQGIVRNPLASPDILGVNHAASLASVGALLL
                     MPSLPVMVLPLLAFAGGMAGLILLKMLAKTHQPMKLALTGVALSACWASLTDYLMLSR
                     PQDVNNALLWLTGSLWGRDWSFVKIAIPLMILFLPLSLSFCRDLDLLALGDARATTLG
                     VSVPHTRFWALLLAVAMTSTGVAACGPISFIGLVVPHMMRSITGGRHRRLLPVSALTG
                     ALLLVVADLLARIIHPPLELPVGVLTAIIGAPWFVWLLVRMR"
     gene            complement(3894..4892)
                     /gene="fecC"
                     /locus_tag="RN951_003982"
     CDS             complement(3894..4892)
                     /gene="fecC"
                     /locus_tag="RN951_003982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dicitrate ABC transporter permease FecC"
                     /protein_id="HDX2528905.1"
                     /translation="MTAIKHPVLLWGLPVAALIIIFWLSLFCYSAIPVSGADATRALL
                     PGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAA
                     LAMALTSALSPTPIAGYSLSFIAACGGGVSWLLVMTAGGGFRHTHDRNKLILAGIALS
                     AFCMGLTRITLLLAEDHAYGIFYWLAGGVSHARWQDVWQLLPVVVTAVPVVLLLANQL
                     NLLNLSDSTAHTLGVNLTRLRLVINMLVLLLVGACVSVAGPVAFIGLLVPHLARFWAG
                     FDQRNVLPVSMLLGATLMLLADVLARALAFPGDLPAGAVLALIGSPCFVWLVRRRG"
     gene            complement(4889..5791)
                     /gene="fecB"
                     /locus_tag="RN951_003983"
     CDS             complement(4889..5791)
                     /gene="fecB"
                     /locus_tag="RN951_003983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418710.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter
                     substrate-binding protein FecB"
                     /protein_id="HDX2528906.1"
                     /translation="MLAFIRFLFAGLLLVISHAFAAMVQDEHGTFTLEKTPQRIVVLE
                     LSFADALAAVDVSPIGIADDNDAKRILPEVRAHLKPWQSVGTRAQPSLEAIAALKPDL
                     IIADSSRHAGVYIALQQIAPVLLLKSRNETYAENLQSAAIIGEMVGKKREMQARLEQH
                     KERMAQWASQLPKGTRVAFGTSREQQFNLHTQETWTGSVLASLGLNVPAAMAGASMPS
                     IGLEQLLAVNPAWLLVAHYREESIVKRWQQDPLWQMLTAAQKQQVASVDSNTWARMRG
                     IFAAERIAADTVKIFHHQPLTVVK"
     gene            complement(5836..8160)
                     /gene="fecA"
                     /locus_tag="RN951_003984"
     CDS             complement(5836..8160)
                     /gene="fecA"
                     /locus_tag="RN951_003984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate transport protein FecA"
                     /protein_id="HDX2528907.1"
                     /translation="MTPLRVFRKTTPLVNTIRLSLLPLAGLSFSAFAAQVNIAPGSLD
                     KALNQYAAHSGFTLSVDASLTRGKQSNGLHGDYDVESGLQQLLDGSGLQVKPLGNNSW
                     TLEPAPAPKEDALTVVGDWLGDARENDVFEHAGARDVIRREDFAKTGATTMREVLNRI
                     PGVSAPENNGTGSHDLAMNFGIRGLNPRLASRSTVLMDGIPVPFAPYGQPQLSLAPVS
                     LGNMDAIDVVRGGGAVRYGPQSVGGVVNFVTRAIPQDFGIEAGVEGQLSPTSSQNNPK
                     ETHNLMVGGTADNGFGTALLYSGTRGSDWREHSATRIDDLMLKSKYAPDEVHTFNSLL
                     QYYDGEADMPGGLSRADYDADRWQSTRPYDRFWGRRKLASLGYQFQPDSQHKFNIQGF
                     YTQTLRSGYLEQGKRITLSPRNYWVRGIEPRYSQIFMIGPSAHEVGVGYRYLNESTHE
                     MRYYTATSSGQLPSGSSPYDRDTRSGTEAHAWYLDDKIDIGNWTITPGMRFEHIESYQ
                     NNAITGTHEEVSYNAPLPALNVLYHLTDSWNLYANTEGSFGTVQYSQIGKAVQSGNVE
                     PEKARTWELGTRYDDGALTAEMGLFLINFNNQYDSNQTNDTVTARGKTRHTGLETQAR
                     YDLGTITPTLDNVSIYASYAYVNAEIREKGDTYGNLVPFSPKHKGTLGVDYKPGNWTF
                     NLNSDFQSSQFADNANTVKESADGSTGRIPGFMLWGARVAYDFGPQMADLNLAFGVKN
                     IFDQDYFIRSYDDNNKGIYAGQPRTLYMQGSLKF"
     gene            complement(8247..9200)
                     /gene="fecR"
                     /locus_tag="RN951_003985"
     CDS             complement(8247..9200)
                     /gene="fecR"
                     /locus_tag="RN951_003985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fec operon regulator FecR"
                     /protein_id="HDX2528908.1"
                     /translation="MNPLLTDSRRQALRSASHWYAVLSGERVSPQQEARWQQWYEQDQ
                     DNQWAWQQVENLRNQLGGVPGDVASRALHDTRLTRRHVMKGLLLLLGAGGGWQLWQSE
                     TGEGLRADYRTAKGTVSRQQLEDGSLLTLNTQSAADVRFDAHQRTVRLWYGEIAITTA
                     KDALQRPFRVLTRQGQLTALGTEFTVRQQDNFTQLDVQQHAVEVLLASAPAQKRIVNA
                     GESLQFSASEFGAVKPLDDESTSWTKDILSFSDKPLGEVIATLTRYRNGVLRCDPAVA
                     GLRLSGTFPLKNTDAILNVIAQTLPVKIQSITRYWINISPL"
     gene            complement(9197..9718)
                     /gene="fecI"
                     /locus_tag="RN951_003986"
     CDS             complement(9197..9718)
                     /gene="fecI"
                     /locus_tag="RN951_003986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor FecI"
                     /protein_id="HDX2528909.1"
                     /translation="MSDRATTTASLTFESLYGTHHGWLKSWLTRKLQSAFDADDIAQD
                     TFLRVMVSETLSTIRDPRSFLCTIAKRVMVDLFRRNALEKAYLEMLALMPEGGAPSPE
                     ERESQLETLQLLDSMLDGLNGKTREAFLLSQLDGLTYSEIAHKLGVSISSVKKYVAKA
                     VEHCLLFRLEYGL"
BASE COUNT         2207 a         2749 c         2823 g         2174 t
ORIGIN      
        1 agcgtctgcc ccgattacgc tgaacctcac gtgagatcgt cgaaggactg cgattcagcg
       61 cagtagctat cgcacgaatg ctcattttgg ctgacaaacc agctcgtatc tcctcgcgct
      121 cagacagtgt caggtgagct acagcccgct tacgctcatg gggttttatg ccgccagtat
      181 cccttaacat agtgaagatc gttccgggtt ttgaacccag gatattcgct atttcactga
      241 agcctgttcc gttcttccat agttcaaaaa cagaggcttt ttcctctgct gtaaatgttc
      301 gtctcattca aaaaacctcc gcaaccccat gttttcacat aactgttgcg ttgaccaatt
      361 gaatctacaa ccgcgctctt gatgtcagac tccctgaaca gttttcgata atcgggaaac
      421 tcagggcgcg ttatcctgtg gccactctct gccatgtgtt cggggtccat cgcagtagct
      481 acaaatactg gaaaaaccgt cctgaaaaac cagacggcag acgggctgta ttacgcagcc
      541 aggtacttga actgcatggc atcagccacg gctctgccgg agcaagaagc atcgccacaa
      601 tggcaaccca gagaggctac cagatggggc gctggcttgc tggcagactc atgaaagagc
      661 tggggctggt cagttgccag cagccgactc accggtataa gcgtggcggt catgagcacg
      721 ttgctatccc gaatcatctt gagcgacagt tcgccgtaac ggaaccaaat caggtgtggt
      781 gcggtgatgt gacctatatc tggacgggta agcgctgggc gtacctcgcc gttgttctcg
      841 acctgttcgc aagaaaacca gtgggctggg ccatgtcgtt ctcgccggac agcaggctta
      901 ccatgaaagc actggaaatg gcatgggaaa cccgtggtaa gcccggcggg gtgatgttcc
      961 aagcgatcaa ggcagtcatt atacgagcag gcagttccgg cagttactgt ggcgataccg
     1021 gatcaggcag agtatgagtc ggcgtggaaa ctgctgggat aacagcccaa tggagcgctt
     1081 cttcaggagt ctgaagaacg aatgggtgcc ggtggtgggt tacgtaagct tcagcgaggc
     1141 agctcacgcc ataacggact atatcgttgg atattacagc gcactaagac cgcacgaata
     1201 taatggtggg ttaccaccaa acgaatcaga aaaccgatac tggaaaaact ctaacgcgga
     1261 ggccagtttt agttgaccac aacagactac ctgaagggag ccgcggtcgc ctagcagttg
     1321 cagtagcagg agatcatcca gccgcagtac aggtcacgat gactctggtt aatgataccg
     1381 gctttgaccc cgtattttcc ggctctatcg ctgaatcatg gcgtcagcag ccgtgcacac
     1441 catcctattg ttgtgactgg gaggctgcca ccatgcttcg cgctttccct ctggcgaaaa
     1501 agggagaagg acgggcccgt ctgccttcac tttatgccag cttcggtaag ctgggtgaga
     1561 caccgactca tgaagatatc attgataaca atcgatccat caactggcct gtataacgtg
     1621 gctgccggtg attaagaaag ctgcacctac ctaagtagta gcaaacgcac actttttaga
     1681 aaaatcgatg gtcagaaact ggattagcaa ttccgttcca gggttgcttt tgatttacgt
     1741 tggcgtctga tcattgattt atcctcaaaa gcccaacctc attggtaatg aaccagctcc
     1801 gtgaatgtcc gctctggcac agagcgaaat tttttgatct cccccctgaa atctaaactt
     1861 agtcatgtca cgtttttggg tttctaaaat tttaacttcg cgtttttcgt tgccgtaagg
     1921 gttatacaga aatgtccgtt aagcagagtt caaaattgat tgccgtgatc acgactggtt
     1981 tgaaagccgc gcccaagcct gtacagctct ggtttgcgtt gattatgaac ctgtcagcct
     2041 aaagcaagcg gatggacgat gagtattggt aatctttcag agtccggaaa agttcagccc
     2101 cagtctgaac aggcttgctg gcgccagtcc agtttcattc agtcgtggtt tggttcttac
     2161 ggcctgtgca atctacctca ttaggcacat cggcctgcca gataccggct cggggtgtat
     2221 ttccgcttcc acgctgaata ctgttctcag caatcctggg gtcatcacct cttctggtgt
     2281 gccttgcgcc ataacatgtc cgtttgccat taccaccagt tgatcgcagt accggctagc
     2341 ctgattaagg tcgtgcagca cagcgaccac cgttttcccc tgagtccgga gttcgcccat
     2401 caaccgcatc aggtccacct ggtgattgat atcaagatag gtggttggct catcaagtaa
     2461 tacaacgggc gtattctggg ccaggaccat cgccagaaat gcgcgctggc gctgaccgcc
     2521 ggaaagctcg gttaaccgac gaacggcaag atgattgatc cgggtctggt tcatggcgac
     2581 attaactcgt gcattgtctt cagcggagag acgcccccag agtgacagcc agggattacg
     2641 accatacgaa accagctcct ggactgtgat cccctctggc gttaaatggt gctgaggcag
     2701 cagcgaaagc ctgcgggcca actggcgtga tgagagcata tttatgggat tatcgccgag
     2761 aaatacggtg ccagactgcg gcattaaaag ccgcgaaaaa cagtttaaca gcgtcgattt
     2821 cccgcaaccg ttaggaccga tcagggcggt gatcttcccc gttggcagtg agagtgaaac
     2881 gtcgttaagt accttgtctg tcccgtaact gaccgtcaga ttttcagttc gtaaagtcat
     2941 ttatcgcatt ctcacaagca accagacaaa ccacggcgca ccgataatgg cggtcagcac
     3001 gccaaccggg agctccagtg ggggatgaat aattctcgcc agcagatcgg caaccaccaa
     3061 cagcaacgca cctgtcaggg ccgaaacagg cagcagcctg cggtgacgtc caccggtgat
     3121 gctacgcatc atatgcggca ccacgagacc aataaagcta atcgggccgc aggcggccac
     3181 gccggtagat gtcatggcga cagctagtaa caaagcccag aatcgggtat ggggcaccga
     3241 cacaccgagc gtggtggcgc gcgcatcgcc gagtgcaagg aggtcgagat cgcggcaaaa
     3301 actcaggctc agcggcagaa ataaaatcat cagcgggatg gcaatcttca caaagctcca
     3361 gtcacggccc cataagctgc cggtcagcca cagcagggcg ttgttcacat cctgcgggcg
     3421 cgagagcatc agataatccg tcaggctggc ccagcatgca gaaagcgcca cgccggtgag
     3481 cgccagcttc atcggctggt gggtctttgc cagcatcttc agcaatatca accccgccat
     3541 gccgcccgca aaggccagca gcggcagcac catcacgggc agtgacggca taagaagtag
     3601 agcccccaca gaggccaggc tggcggcatg gttaacgccg agaatatccg gtgatgccag
     3661 agggttgcgc acaatcccct gtatcagcac gcccgccaca gcgagggctg caccgacaaa
     3721 cagtgccagc agcaagcgcg gcagtcggta ctccatcaat acataataat gctcgcgtcc
     3781 ggcctgccag tcggtcagca gcgcgcgcca cggcacgggg atcactccca tatggagtga
     3841 taacagcgca cagcccgcca gggcaagggt gatgaaaata accagcgcaa ttttcatcct
     3901 cgcctcctca caagccagac aaagcaaggg ctgccaatca gcgccagcac tgcgcctgcg
     3961 ggcagatctc cggggaaggc cagcgcgcgt gcgagtacat ctgccagcag catcagcgtg
     4021 gcccccagca gcatgctcac tggcagtacg ttgcgctgat cgaagcctgc ccagaagcgc
     4081 gccagatgtg gcaccagcag accgataaac gccaccggac ctgccacgct gacgcacgca
     4141 ccaaccagaa gcagcactaa catattgatg accaaacgta gcctcgtcag gttcactccc
     4201 agcgtatggg cggtgctgtc gctgaggttg agcaggttca gttgattcgc cagcagcaac
     4261 acgacaggga ctgcagtgac caccaccggc aagagctgcc agacatcctg ccagcgggcg
     4321 tgggacactc cgcctgccag ccagtaaaag atgccgtaag catgatcttc ggccagcagc
     4381 agggtgatgc gggtaaggcc catacaaaag gccgacagcg cgatacccgc gaggatcagt
     4441 ttgtttctgt catgggtatg acgaaatccg cctcctgcgg tcatgaccag cagccagctc
     4501 acgccgcccc cgcatgccgc gatgaacgac agagaatagc ctgcaatcgg cgtcggactc
     4561 agcgcgctgg taagcgccat agccagcgcc gcgccgctgt taatgccgag cagtgaagga
     4621 gaggccattg ggttgtgggt cagggtttgc agcagcgtgc ccgcgagcgc caggcttgcg
     4681 ccgatcagaa cggcgaccag gcttcgtggc aaacgaaggt tttgcaccag cgcttctggt
     4741 agcgttggcg tgtgtccagg cagcagggcg cgggttgcat ctgctccgga aacaggaatg
     4801 gccgagtagc aaaacagact cagccagaaa ataataataa gtgctgcaac gggaagcccc
     4861 cacagcagca ccgggtgttt tatcgcggtc atttcacaac ggtaagcggc tgatggtgga
     4921 agatttttac cgtgtcagcg gcaatacgct ctgcagcaaa aataccgcgc atccgcgccc
     4981 aggtgttact gtcgaccgaa gcaacctgct gcttctgcgc ggcggttaac atctgccaga
     5041 gcggatcttg ttgccagcgt ttaacaatgc tctcttcgcg atagtgggca accagcagcc
     5101 aggcaggatt gaccgccagc agttgctcca ggccgatgga cggcatggac gcacccgcca
     5161 tcgcagcggg aacgttcagc cccagagagg ccagcacgct gccggtccag gtctcctgag
     5221 tatgcaggtt gaattgctgt tcgcgtgatg tgccaaaggc cacgcgtgtc cctttgggaa
     5281 gctggctggc ccactgcgcc atcctctctt tatgttgttc cagacgtgcc tgcatctctc
     5341 gctttttacc caccatttcg ccgatgatag ccgcagattg caaattttca gcgtaggttt
     5401 cgttgcggga cttaagcagc agtaccggcg cgatttgctg caaggcgatg taaacccccg
     5461 catggcgact gctgtcggca atgatcaggt ctggtttcag agcggcaatg gcttccaggc
     5521 tcggctgcgc gcgcgttccg acggactgcc acggtttcag gtgcgcacgc acttcgggca
     5581 ggatgcgttt tgcatcgtta tcgtcggcaa taccgatcgg gctgacgtcc acggcggcca
     5641 gcgcatcggc gaacgagagt tccagcacca caatccgttg tggcgttttt tcgagtgtaa
     5701 acgtgccgtg ttcgtcctga accatggcgg caaaggcgtg gctgatcacc agcagcaggc
     5761 ctgcaaaaag aaaacggata aatgccaaca taatcacatt ccagctaaaa gcccggcaag
     5821 ccgggcgtta acacatcaga acttcaacga cccctgcata tacagcgtgc gcggctggcc
     5881 tgcatagatg cctttgttgt tgtcgtcata agagcggatg aagtagtcct ggtcgaagat
     5941 gtttttcaca ccgaatgcca ggttcagatc tgccatctgc gggccaaagt catacgccac
     6001 gcgtgcgccc cagagcatga agccgggaat gcggccggta ctgccgtcgg cgctctcttt
     6061 caccgtattg gcgttatccg caaactggct ggactggaaa tcgctgttca gattgaacgt
     6121 ccagtttcct ggcttgtagt ccacgcccag cgtgccttta tgtttcgggg agaatggtac
     6181 cagattgccg taggtgtcgc ctttctcgcg gatttccgcg ttcacatacg catagctggc
     6241 gtagatggaa acgttatcaa gcgttggcgt tatcgtaccc agatcgtaac gtgcctgcgt
     6301 ttccagcccg gtatggcgcg ttttgccacg tgcagtgacg gtgtcgttgg tctggttgga
     6361 gtcgtactga ttgttaaagt taatcaggaa cagccccatt tccgccgtca gcgcgccgtc
     6421 gtcgtagcgg gtaccgagtt cccaggttcg cgctttttcc ggttccacat tgccgctttg
     6481 cacagccttg ccaatctggc tgtactgtac ggtgccgaac gagccttcag tgtttgcata
     6541 aagattccag ctgtcagtca ggtgatagag cacgttcaac gccggaagcg gtgcgttata
     6601 gctcacttct tcgtgcgtgc ctgtgatggc gttgttctgg tatgactcga tatgttcgaa
     6661 acgcataccc ggcgtgatgg tccagttgcc gatgtcgatt ttgtcatcca gataccaggc
     6721 gtgcgcctcg gtgccggaac gcgtatcgcg gtcgtaaggg cttgagccgg acggcaactg
     6781 cccgctgctg gtggcggtgt agtaacgcat ttcatgcgtt gattcattca aatagcgata
     6841 gcccacgccc acttcgtgcg cggaagggcc gatcataaag atctggctgt agcgtggctc
     6901 aataccgcgc acccagtagt tacgcggcga gagggtgatg cgtttgcctt gctccaggta
     6961 gccgctgcgc agggtttggg tgtagaaccc ctgaatgttg aatttatgct ggctgtctgg
     7021 ctggaactgg tagcccaggc tcgccagctt gcgacgaccc cagaagcggt catacgggcg
     7081 ggtggattgc cagcgatcgg cgtcgtaatc cgcgcgagac aggccaccgg gcatgtcggc
     7141 ttcaccgtcg taatattgca gcaggctgtt gaaggtgtgc acctcatccg gcgcatattt
     7201 gcttttcagc atcaggtcgt cgatgcgggt ggcgctgtgc tcgcgccagt cactgccgcg
     7261 cgtgccggag tagagcagcg cggtgccaaa accgttgtcc gctgtgccgc ccaccatcag
     7321 gttgtgcgtc tctttcgggt tgttttgtga agaggttggg ctgagctgac cttccacgcc
     7381 cgcctcgata ccaaagtcct gcggaatggc acgggtaaca aagttcacca cgccgcccac
     7441 gctctgcggt ccgtaacgca ccgcaccacc accgcgtacc acgtcaatgg catccatgtt
     7501 gccgagcgaa acgggagcca gtgaaagctg cggctgaccg taaggggcga aggggacggg
     7561 gatgccgtcc atcaggacgg tcgagcggct ggcgaggcgc gggttcaggc cccggatgcc
     7621 aaagttcatc gccaggtcgt ggctgccggt gccgttgttt tccggcgcgc tgacgccagg
     7681 gatgcggtta agtacctcac gcatggtggt tgcgccggtt ttggcgaaat cctcacggcg
     7741 gatcacgtca cgcgcgccag catgttcaaa tacgtcgttt tcacgcgcat cacccagcca
     7801 gtcgccgacc acggtcaggg catcttcttt tggtgcgggc gcgggctcca gcgtccagct
     7861 gttatttccc agcggtttta cctgcagtcc gctgccgtcc agcagttgtt gcaggccgct
     7921 ctcgacgtcg taatcgccgt gcaggccgtt gctctgcttg ccgcgcgtca ggctggcgtc
     7981 aaccgagagg gtaaatccgc tgtgtgcggc atactgattg agcgctttat cgagcgatcc
     8041 cggtgcgata ttaacctgtg cagcaaaagc ggaaaacgag agaccggcca gcggcagcag
     8101 gctcaggcga atggtgttaa ccaaaggtgt tgttttacga aaaacgcgta acggcgtcat
     8161 accttcccca tcatcatttt tgttgtgttc agctatgagt cgaacgagaa gggtaaaaag
     8221 gacaatcgaa ataagaatta ttttccttac agtggtgaaa tgtttatcca gtaccgcgta
     8281 atagactgaa ttttaacggg aagcgtttgc gcgataacgt tcaggatcgc atcggtattt
     8341 ttcagcggga acgtcccgct caggcgcagc ccggcaacgg cgggatcgca gcgcagcacg
     8401 ccgttgcggt aacgggttag cgtggctatc acctcaccca gcggtttatc gctgaagctc
     8461 aggatgtcct tcgtccagct tgtactctcg tcatccagcg gtttcactgc gccaaactca
     8521 gaggcgctga actgcaggct ttcaccagcg ttcacgatgc gtttttgcgc gggggcactg
     8581 gcgagaagca cttccacagc gtgctgctgc acgtcaagct gcgtgaaatt atcctgctgg
     8641 cggacggtaa attctgtccc taaagcagtg agctggccct gacgggtcag gacacggaag
     8701 gggcgttgca gggcatcttt cgcggtagta atggcgattt caccgtacca gagccggacg
     8761 gtgcgctgat gcgcatcaaa acgcacatcc gccgcgcttt gggtattcag cgtgagcagg
     8821 gagccatctt ccagttgctg acggctgact gtgcctttgg cggtgcggta atctgcccgc
     8881 agaccttcgc cggtttccga ctgccagagc tgccagcctc cgccagcgcc gagcaacagc
     8941 agtaatcctt tcatcacgtg acggcgggtg aggcgggtat cgtgcaacgc ccggctggca
     9001 acgtcgccag gcacaccgcc aagctggttg cgcaggtttt caacctgctg ccaggcccac
     9061 tggttatcct gatcctgttc ataccactgt tgccagcgcg cttcctgttg tgggctgacg
     9121 cgctcgccgc ttagcacggc ataccagtgg gaagctgaac gcagcgcctg acggcgggaa
     9181 tcggttaaca aaggattcat aacccatact ccagacggaa cagcaggcag tgctcgacgg
     9241 ctttcgccac gtattttttc acggagctga tggaaacacc gagtttgtgc gcaatctcgc
     9301 tgtatgtcag accatccagt tgcgaaagca gaaacgcttc acgtgttttg ccgtttagcc
     9361 cgtccagcat gctgtcgagg agttgtaggg tctcgagttg gctttcgcgt tcctcaggtg
     9421 aaggcgctcc cccctccggc ataagcgcca gcatctccag atacgctttt tccagcgcgt
     9481 ttcggcgaaa caggtccacc atcacgcgtt tggcgatagt gcagaggaag gagcgaggat
     9541 cgcggatcgt cgagagcgtt tcgctgacca ttacccgcaa aaaagtgtcc tgggcaatgt
     9601 catctgcatc aaaagcagac tggagtttgc gcgtcagcca gcttttcaac cagccgtgat
     9661 gtgtgccata aagcgactcg aacgttaagg aagctgtggt agtggcgcgg tcagacatgc
     9721 ggagtgcatc aaaagttaat tatcacgtag tcatattaat atgagaatgg ttatcattac
     9781 aattggaaat aaaattgttt ccaatagaca tttttaacat gttgtttttc taagtgttat
     9841 aaggtaggta taaaatggga tggagcctct gcttctggca tgtgtcggtc agaatgactc
     9901 atgatgtggt ctgctattat tgacatcctc actgccctaa aggatgggga ttt
//
LOCUS       DAPOAV010000126         9707 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.126, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000126 DAPOAV010000000
VERSION     DAPOAV010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9707
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.126"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..368
                     /locus_tag="RN951_003987"
     CDS             <1..368
                     /locus_tag="RN951_003987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1-like element IS1X2 family transposase"
                     /protein_id="HDX2528910.1"
                     /translation="WGYVGAKSRQRWLFYAYDRIRRTVVAHVFGERTLATLERLLSLL
                     SAFEVVVWMTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSK
                     SVELHDKVIGHYLNIKHYQ"
     gene            complement(384..539)
                     /locus_tag="RN951_003988"
                     /pseudo
     CDS             complement(384..539)
                     /locus_tag="RN951_003988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312018.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation protein"
     gene            complement(814..2178)
                     /gene="tdcG"
                     /locus_tag="RN951_003989"
     CDS             complement(814..2178)
                     /gene="tdcG"
                     /locus_tag="RN951_003989"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HDX2528911.1"
                     /translation="MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSH
                     IVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGA
                     HIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEELLSKTYYSVGGGFIVEEEHFGLS
                     HDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHD
                     GIERGMNTEGVLPGPLNVPRRAVALRRQLVSSDNISNDPMNVIDWINMYALAVSEENA
                     AGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAGAIGALYKMNASISG
                     AEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPC
                     IERNAINAVKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIK
                     VVCG"
     gene            complement(2250..2639)
                     /locus_tag="RN951_003990"
     CDS             complement(2250..2639)
                     /locus_tag="RN951_003990"
                     /EC_number="3.5.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312020.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enamine/imine deaminase"
                     /protein_id="HDX2528912.1"
                     /translation="MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPA
                     DVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATY
                     PTRSCVQVARLPKDVKLEIEAIAVRSA"
     gene            complement(2653..4947)
                     /gene="tdcE"
                     /locus_tag="RN951_003991"
     CDS             complement(2653..4947)
                     /gene="tdcE"
                     /locus_tag="RN951_003991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-ketobutyrate formate-lyase/pyruvate
                     formate-lyase"
                     /protein_id="HDX2528913.1"
                     /translation="MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGD
                     ESFLAEATPATTELWEKVMEGIRIENATHAPVDFDTNIATTITAHDAGYINQPLEKIV
                     GLQTDAPLKRALHPFGGINMIKSSFHAYGREMDSEFEYLFTDLRKTHNQGVFDVYSPD
                     MLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDL
                     EATIRLREELAEHRHALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNG
                     GAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSG
                     DPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEELPIAFKKYA
                     AQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYA
                     INGGVDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDK
                     YSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDG
                     EYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNT
                     PDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKE
                     DPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGY
                     AVRFNALTREQQQDVISRTFTQAL"
     gene            complement(4981..6189)
                     /gene="tdcD"
                     /locus_tag="RN951_003992"
     CDS             complement(4981..6189)
                     /gene="tdcD"
                     /locus_tag="RN951_003992"
                     /EC_number="2.7.2.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417585.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate kinase"
                     /protein_id="HDX2528914.1"
                     /translation="MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAF
                     LSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITD
                     EVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLP
                     WKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQS
                     VDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLS
                     SDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLI
                     RRLVMEHLAVLGLEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHL
                     GKVNAPAEFA"
     gene            complement(6215..7546)
                     /gene="tdcC"
                     /locus_tag="RN951_003993"
     CDS             complement(6215..7546)
                     /gene="tdcC"
                     /locus_tag="RN951_003993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine transporter TdcC"
                     /protein_id="HDX2528915.1"
                     /translation="MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRA
                     GFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITF
                     LYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLM
                     VKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIM
                     VFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLF
                     TLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGH
                     YLGTLEGLNGLVLKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAM
                     GAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF"
     gene            complement(7568..8557)
                     /gene="tdcB"
                     /locus_tag="RN951_003994"
     CDS             complement(7568..8557)
                     /gene="tdcB"
                     /locus_tag="RN951_003994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional threonine ammonia-lyase/L-serine
                     ammonia-lyase TdcB"
                     /protein_id="HDX2528916.1"
                     /translation="MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEI
                     FLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGK
                     VVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIA
                     GQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAA
                     SFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQR
                     NKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRVSQITGFVDA"
     gene            complement(8656..9594)
                     /gene="tdcA"
                     /locus_tag="RN951_003995"
     CDS             complement(8656..9594)
                     /gene="tdcA"
                     /locus_tag="RN951_003995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TdcA"
                     /protein_id="HDX2528917.1"
                     /translation="MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIIND
                     IEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFG
                     FPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKL
                     QDLHVEPLFESEFVLVASKSRTCTGTTTLESLKNEQWVLPQTNMGYYSELLTTLQRNG
                     ISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAV
                     WSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVG"
BASE COUNT         2523 a         2518 c         2283 g         2383 t
ORIGIN      
        1 agtggggcta cgtcggtgct aaatcacgtc agcgctggct gttttacgcg tatgacagga
       61 tacggaggac ggttgtggcg cacgtcttcg gtgaacgcac tctggccaca ctggagcgtc
      121 ttctgagcct gctgtcggcc tttgaggtcg tggtatggat gacggatggc tggccgctgt
      181 atgaatcccg cctgaaggga aagctgcacg taatcagcaa gcgttacact cagcgcattg
      241 agcgacataa cctgaatctg agacaacatc tggcaaggct gggacggaag tcactgtcgt
      301 tctcaaaatc ggtggagctg catgacaaag tcatcgggca ttatctgaac ataaaacact
      361 atcagtaagt tggagtcatt accccccgcg ccaatcgcca tcccgatact cataatcacc
      421 cagccggtgt cagtactgtc gaatttgatc gcttctcgcc actcgctctc actcattcca
      481 gcacgacccg ccggggtcga agcgtctgca atgacgcctt tattcgatgc aatttccata
      541 atttctcgct caatattttg tagggcttat tatttttttc cgagccgcat caaggcgata
      601 tgcggtctac gtttttgcag gcgagttatt agaataaaga aatgatacgc gcgaggtcag
      661 agaaaatctt cacaatcaag actttgaaat aacggagatg gataagaatt ttctactaaa
      721 ttaatcgcag gagaatattc attctctatt tgcggcagat cacaaaaaaa aggtgcacat
      781 ttgtgcaccc aaggatgaaa gctgacagca atgtcagccg cagaccactt taatggccag
      841 tcctccgcgt gatgtttcgc ggtatttatc gttcatatct ttgccggttt catacatcgt
      901 ctcgatcact ttatcgagtg aaacacgcgg tgccgaggtg cggcgcatcg ccatccgcgc
      961 ggcgtttact gctttcacgg cattaatggc attacgttca atgcacggga tttgtacctg
     1021 tccggcaacc ggatcgcagg tcagcccaag gttatgctcc atcgcgattt ccgccgcatt
     1081 gcatacctgc gccggactgc cgcccagtag ttcagttaac cctgccgccg ccattgaaca
     1141 ggccacgcca atctccccct gacagccgac ttccgcgcca gagatggagg cgttcatttt
     1201 atacagcgcg ccaatagccc ccgcggccag aaaatagcgg gcaattgacc gctcgtttac
     1261 cggacgacgg aacttatcgt aataagccag tactgccgga ataatgccgc acgcaccgtt
     1321 agtcggtgcc gttaccacgc gcccgccagc tgcgttttct tcactaaccg ccagcgcgta
     1381 catgttgatc cagtcgatga cattcatcgg atcgttagag atgttatcgc tggaaaccag
     1441 ctgacgacgc agcgctacgg cacggcgcgg cacattgagc ggaccaggca gcacgccttc
     1501 agtgttcatc ccacgttcaa taccgtcatg catcacttgc cagatacggg caaaaccggc
     1561 gtcaatttcc gctttgctgc gcagcgctag ctcgttgtgc atcatcagac cagatataga
     1621 caggccgttg taatcacaca ttttcagcag ttcacctgct gagtggaaat cgtaaggtac
     1681 ggacgtttcg acatcgtgcg acaggccgaa gtgttcttct tcgacaataa acccgccgcc
     1741 gacagagtaa taggttttac ttaatagctc ttcctgtccc ttccaggcag tgatccgcat
     1801 tccgttctca tggcgaggca acatttcggg atggaagata atgttctttg ctacaggaaa
     1861 atcaacaata tgcgcaccag atgccactgg cagccgcccg ctgcgcgtta ctaactctat
     1921 aaatgcaggg atctcatcaa tgacaacatc ctgcggactg tttcctgcca gtcccatgat
     1981 gatggcgaca tccgtggcat ggcctttgcc cgtcagtgac aacgacccgt acagatcgac
     2041 cacaatatgg ctcgtcgcgg ttaataagcc gctactttcc agccgatcaa taaaactttt
     2101 tccggcattc attggcccca cggtatgcga actggaggga ccaatcccaa ttttgaaaat
     2161 atcgaatgca ctaatcatat ccacaccctc ggattgccgt tcagtgaagt ggagcggaac
     2221 gaccttacga ccgtcccgct cacgaggctt tacgcactac gtactgcgat ggcttcaatt
     2281 tccagcttca catctttcgg caaacgcgcg acctgcacac agctccgggt cggataggtc
     2341 gcctgatgct catcgaagaa ctgcttatag acttcgttga tggtggcaaa atcattcaga
     2401 tcggtgataa acacggtcat cttgatgata tcgcccacgc tcagcccggc agcaaccacg
     2461 atcgctttga cgttttcgag gcttaaacgc gcctgatctt gcacatcagc cgggatctca
     2521 ccggtctgtg ggcaaaccgg tatttgcccg gaggtgaaga ccatgctgcc taaatcaacg
     2581 ccctgaacat aagggccgat tgcgcctggg gcacgttgcg tttcgataat ctttttcata
     2641 catcctccgg cgtcagagcg cctgggtaaa ggtacgtgaa ataacatcct gttgctgttc
     2701 acgggtcagt gcgttgaagc gcacggcgta gccagagaca cggattgtca ggttaggata
     2761 tttttccggg tgctcgatgg catccagcag catttcccga ttcattacgt tgacgttgag
     2821 gtgttgaccg ccttcgacat ccgcttcgtg gtggaaatac ccatccagca ggccgacaag
     2881 gttggtttta cgtactggat cttctttgcc cagcgccgca ggaacgattg agaaggtgta
     2941 cgagatccca tctttggcgt aggtgaacgg cagtttcgcc accgacgtca atgaggccac
     3001 ggcacctttg cggtcacgac catgcatcgg gttagcgccc ggcgcgaacg gtgttccggc
     3061 gcgacgaccg tccggcgtat taccggtttt ctggccgtac accacgttag aagtgatagt
     3121 cagaatcgac tgggtaggga cggcgttgcg ataggttggc agcgctttaa ttttcttcat
     3181 aaagcgttca accaggtcgc aggcaatgct gtctacgcgc tcgtcgttgt tgccgtactg
     3241 cggatattca ccgtcgattt caaagtccac cgccaggccg ttttcgtcac ggattggttt
     3301 cacgcgggca tatttgatgg cagacaggga gtccgtcgcc accgacaggc ccgcgatgcc
     3361 gcatgccata gtgcgataga catcacgatc gtgcagcgcc atcagcgaag cttcgtagct
     3421 gtacttgtcg tgcatgtagt gaatgatatt cagcgcgctg atgtactgca ccgccagcca
     3481 gtccatgaag tgatcgaggc tgtccatcac tttgtcgtaa tccagcacgt cgtccatcag
     3541 cggtgctgtt ttcggcccga cctgaatctt cagcttctcg tccaccccgc cgttaattgc
     3601 gtagagcagc gttttcgcca ggttagcgcg tgcaccaaag aactgcattt gcttaccaat
     3661 caccattggg ctgacgcagc aggcaatcgc gtaatcgtcg ctgttgaagt cagtacgcat
     3721 cagatcgtca ttttcatact gcaaggaaga ggtgacgatc gacacctgcg cggcatattt
     3781 tttgaaggca atcggtaatt cttccgacca aagaatggtc aggttaggtt ccggtgccgg
     3841 ccccatagtg tgcagggtgt gcaaatagcg gaaggagttt ttggtcacca gcgtacgacc
     3901 gtccagcccc atcccgccga tcacttccgt cgcccagatt gggtcgccgg agaacagcga
     3961 atcaaattcc ggtgtacgca ggaagcgtac catacggatc ttcatgatga agtgatcgat
     4021 cagttcctgt gcctgctgct cattgagtac gccagcttta aagtcgcgct caatgtagat
     4081 atcgaggaac gatgccgtgc ggcccagcga catcgcgccg ccattttgcg atttcactgc
     4141 cgccagataa gcgaagtaga gccactgcac cgcttcctgc gcattctgcg ccgggcgaga
     4201 gatatcaaag ccatatttcg ccgccatttc ctgaatctgc aacagcgcat gacgatgctc
     4261 tgccagctcc tcacgcagac ggatggtggc ttccagatcc tcgccttttt ccagacgaga
     4321 ctggagatcg gcaaattgca gttcgcgttc acgtaccaga taactgatgc catacagcgc
     4381 tacgcggcga tagtcaccga taatgcgccc acggccatag ccatctggta aaccggtcag
     4441 cacgccagat ttacggcagc gcagcatatc cggtgagtaa acatcaaata cgccctggtt
     4501 atgggtttta cgcagatcgg taaacagata ttcaaattca ctgtccattt ctcggccata
     4561 ggcgtggaat gaacttttaa tcatattaat gccaccgaac gggtgtagcg cacgtttcaa
     4621 cggcgcatcc gtttgcaggc caacaatttt ttccagcggc tggttaatat atcccgcatc
     4681 atgagcggta attgtggtgg caatattggt atcgaaatca accggcgcgt gggttgcatt
     4741 ttcgatacgg atgccttcca ttactttttc ccacaattcc gtggtggcag gcgtcgcttc
     4801 ggcgaggaaa gattcatcgc cttcatacgg tgtatagtta tgttgaataa aatcgcggac
     4861 attaatttcg tttttccagt ccgtaccttt aaagccaagc catgcgtcgg cgtacagctt
     4921 atcgctggta tcaatatcta ccttcatgaa aaataatctc tctacaatac ttcaactaaa
     4981 ttatgcaaat tctgcgggcg cgttaacttt gcctaaatga atggcatcca aagcaatcat
     5041 tttttcttcg ttagtcggaa taacggcaca aatgacacgc gcattttcac tggaaacaat
     5101 tcgctcacca caggagttag agcgattatt catttctgta tcaatctcta agcctaatac
     5161 agccaaatgt tccatgacca gacgacgaat taagcttgaa ttctctccta ttccgccggt
     5221 gaatataatt ccatccaggc gacgtaatga agctgcgtgt ccggcaatat gacgggcaat
     5281 tcggtgaaca aaggttttaa ttgccagttg cgcgcgttcg tgaccttcat gccaggcttt
     5341 ttccagaaca cgtaaatccg aagaaagacc ggaaatacct aataatcccg actctttatt
     5401 cactacgcgt tccaggtcac ccaggctctg gttggtttgg ctggcgaccc aggacatcgc
     5461 accaaagtcg acatcgccac tgcgggtacc catcatcaag ccttccagcg gcgtcattcc
     5521 cattgaggta tcaacactct gaccgttgcg aaccgcgcag attgacgcgc cattgccaag
     5581 atgcgccaca accaggccgg agtcatcttc cgccagattc agcagcgaat gtgcgcgctg
     5641 ggaaacatag cggtgcgacg tgccgtggaa accataacgg cgtacaccta actcttcata
     5701 atatttccac ggcaggccgt ataaataagc ttccggagcc atcgtctggt ggaaactggt
     5761 atcaaatacc gccacctgag ttacgcccgg aaataattgc tgcgccgatt caataccact
     5821 taaattggcg taattatgca ggggtgccag tggagaaacg cgacggatat tatcaatgac
     5881 ttcatcggta ataatggcgg actcggtaaa aatactgccg ccgtgagcga tgcggtggcc
     5941 aattaaggcc acactgtcat ttaaattccg tttttccagt tcaaatgcaa ttgccttcaa
     6001 tgcaccttcg tagctgtggt gagccagcgg tgctggctct cccccattta cggataagaa
     6061 tgcattttcc gagttaatac cgtcggcaat acctgacatt aatacttcac agtcgctggc
     6121 atcgagcacg gaaaacttaa tcgaagacga accacagtta ataaccaaaa caaccggaaa
     6181 ttcattcatc tcttttctca tcctgagtta cggattaaaa cagtttgtat acgatgttca
     6241 ggatggtcag cagaccaatc acggtaacaa acacgttatc cagacgacca cggtatttcg
     6301 ccagagacgg cgctttacgg atggcataca tcggcaacag gcacagcagg gatgcgataa
     6361 tcggtgcgcc catggcttca atcaggtcaa ggatgttcgg gttggcgtag gcaacaaccc
     6421 aggtggagcc catgatgaag atcatgctga tagtgttcag tttacccagc gacactttag
     6481 ttttgtcgcc tttataacca aacttcagga ccaggccatt cagaccttcc agcgttccca
     6541 gatagtgacc gaagaaagat ttgaagatag ccacgagtgc gatgatggaa gccgcatatt
     6601 ccagtgtaat cgcgaacgtt gttttggtac cggtcatgga cgcaaagtgg ttagccagat
     6661 aagaaagcac tggaatattc tgcgctttgg cttccgccat gttggccgga gacagagtaa
     6721 acaggcagct aaaggcaaag aacatcacca ctgcaaccat cagcatgctg gcacgagaaa
     6781 tgatttggga acatttacgt tcggtgaagt cgcgaccgaa gtctttctca tactcttcac
     6841 gcttagaaac cacgaaggaa gagacgattg gcgagaagtt aaaggagaaa accatgatgg
     6901 aaatccccag ccagacagtg atcaggatac cgtcatgacc ggttaacgac agcgaaccga
     6961 ggtcaacctg gtcgataact gcagagttcc agtaagggat cagcgacaaa gaaatcagca
     7021 ccaggctggc gataaacggc cataccaggt agctcatcac tttaaccatc agatccttac
     7081 caaaccagat gacgaaagcc atcagcagca acaggaacag cgccacaaag ccgcgattca
     7141 gcggtgcaaa gccgagctgg ttttcccaga acgtcataaa ggtattggta atagtaacgc
     7201 cataaatcca cagcagtggg caaatcgcga agaagtacag gaacgtgata accacgccgc
     7261 cagttttacc aaaatgctct tccaccgttt ccgtaatgtt gccggaaggg ttagagccag
     7321 aaagacacag acgcgccagc gcccggtggc aataaaacgc gatggggtat gccaatacca
     7381 acatcagaag aatcgggatc agtccgccaa aacctgcgcg gatagggaag aacagcaccc
     7441 cggcgccgat tgccgtacca aacaagccta acgtccatgt ggtatctgat ttacgccagg
     7501 acgattgttt tgtctggctg gatacaatgc tatctgaagt actcatatcc tatcctcaac
     7561 gaattaatta agcgtcaacg aaaccggtga tttgagagac gcgagaaaga tcgatattgc
     7621 cgccggaaat aatactgacg gtttttctgt tttgaatata ttggtctaat ttaccgctta
     7681 ataatgcagc acatgccaga gcgcctgcgc cttcggtgac gactttattg cgctgaatta
     7741 aggcaatcat actgtttctg atttcgtctt cgctgaccag cacgatgtca tcgactaatt
     7801 cacgaacgat ttcgtaagtt aaattacccg ggcgggagac atcacaacca tccgccaggg
     7861 tgccggtagt tcggtgcgtg gttatttctc cggagtggaa agaagccgcc atgccgtgaa
     7921 cgttttcaga ctgtacgcca ataacacgaa tggtcgggtt aatagattta attgccaccg
     7981 caataccagc aattaaaccg ccaccaccaa ttggcacaat cacgttatcg acatcataga
     8041 gatcttccat aatttccaga ccaatcgttc cctggccagc aatcactttc ggatcatcgt
     8101 aaggtgggat aaaaatacgg ccttccattt cgacaatttc gctcacttta gcgatagtgt
     8161 cgttgaagtt atcaccatgc agaacgactt ctgcggagta gtcgcacgtt gccgctactt
     8221 tggattttgg cgcacctttt ggcatcacca ctttaccgtc gatacccagc atcgcgcagg
     8281 agagggaaac cccttgcgca tggttgcccg cagaacaggc caccacgcct ttgcgttttt
     8341 ccgcatcggt cagtgaactt aatttattaa atgcgccacg aattttaaat gaacccgtac
     8401 gctgcatatt ttcaaacttc aggaatattt cacctttgca acgttcacta aaatagttgg
     8461 agcgaggcat gcctgtttta taaattcgcc cagccagtcg ttgtttcgct tcaataatgt
     8521 catcaatagc aaccggcaga tcgtatgtaa tatgcattat aaaacctctt cgcctgaatt
     8581 aaatatgtag gtaaccgtaa ccgacacctg caagacagac aggtggatta tttatgttta
     8641 aataaaaaca aataactaac caacttctat taattgcctt cgtctacacc cattataaga
     8701 tgaatactct ttggctaatt ccaccaaaac cgatgctgct tttttaatac gataattttt
     8761 cgaccatacc gcggcatatt gtgccacagg taatgtttct tcaaccggaa tagtaataaa
     8821 ttgattagaa ccaaaaggtg acgtcatatc acaaggaatt acagttaaga aatcagcatt
     8881 gagaacaaga ttataaattg tcacgactga gtcggtttta acgatgtttt caatactgat
     8941 gccatttctt tgtaacgtag taagcagttc gctgtagtac cccatattag tttgtggcaa
     9001 cacccactgt tcgttcttca acgactccag cgtggtggtg ccggtgcatg ttcgggactt
     9061 actggctacc agtacaaact cggactcgaa cagcggctca acatgtaaat cctgaagctt
     9121 catttctgca cttaacgtac caatcgcaaa atccagtcga ccgtcgcgga ttgccggtaa
     9181 gaacgaagac agttgcgctt catacataga aacctgcgct ttcgggaaca cctctttgaa
     9241 cttgttgatc atccctgaca taaaagtaaa accaatcaat gaaggaaaac caaatgagac
     9301 ttccaccacc gcctcagaag acataccgct tatctcatta accatatttt tcatttcacg
     9361 ggtaatggat tcggaacggg agagtaacaa ttgaccggca ggtgttaatg ttacaccggt
     9421 atttttccgc accactaatt ccacaccaaa ataatcttca atatcgttaa tgattttact
     9481 gacggccggt tgagttaacc ctaattcttt tgcagccgag ccgatagaac cacttctaat
     9541 gacttcctga aagactacca ggtgctgcgt tttcggaaga agaatagtgc tcataacgac
     9601 ctacgttaat tacctcattg acggcatgaa gtgtatcaaa atgaaatgaa caggatatgt
     9661 gcgaccactc acaaattaac tttcaatact ttccagagta tcgttat
//
LOCUS       DAPOAV010000127         9625 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.127, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000127 DAPOAV010000000
VERSION     DAPOAV010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9625
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.127"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            112..726
                     /gene="evgA"
                     /locus_tag="RN951_003996"
     CDS             112..726
                     /gene="evgA"
                     /locus_tag="RN951_003996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-sensing system DNA-binding response
                     regulator EvgA"
                     /protein_id="HDX2528918.1"
                     /translation="MNAIIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETL
                     KPDIVIIDVDIPGVNGIQVLETLRKRQYSGIIIIVSAKNDHFYGKHCADAGANGFVSK
                     KEGMNNIIAAIEAAKNGYCYFPFSLNRFVGSLTSDQQKLDSLSKQEISVMRYILDGKD
                     NNDIAEKMFISNKTVSTYKSRLMEKLECKSLMDLYTFAQRNKIG"
     gene            731..4324
                     /gene="evgS"
                     /locus_tag="RN951_003997"
     CDS             731..4324
                     /gene="evgS"
                     /locus_tag="RN951_003997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-sensing system histidine kinase EvgS"
                     /protein_id="HDX2528919.1"
                     /translation="MKFLPYFFLLCCGLWSTISFADEDYIEYRGISSNNRVTLDPVRL
                     SNKELRWLASKKNLVIAVHKSQTATLLHTDSQQQVRGINADYLNLLKRALNIKLTLRE
                     YADHQKAMDALAEGEVDIVLSHLVTSPPLNNDIAATKPLIITFPALVTTLHDSMRPLT
                     SPKPVNIARVANYPPDEVIHQSFPKATIISFTNLYQALASVSAGHNDYFIGSNIITSS
                     MISRYFTHSLNVVKYYNSPRQYNFFLTRKESVILNEVLNRFVDALTNEVRYEVSQNWL
                     DTGNLAFLNKPLELTEHEKQWIKQHPNLKVLENPYSPPYSMTDENGSVRGVMGDILNI
                     ITLQTGLNFSPITVSHNIHAGTQLSPGGWDIIPGAIYSEDRENNVLFAEAFITTPYVF
                     VMQKAPDSEQTLKKGMKVAIPYYYELHSQLKEMYPEVEWIQVDNASAAFHKVKEGELD
                     ALVATQLNSRYMIDHYYPNELYHFLIPGVPNASLSFAFPRGEPELKDIINKALNAIPP
                     SEVLRLTEKWIKMPNVTIDTWDLYSEQFYIVTTLSVLLVGSSLLWGFYLLRSVRRRKV
                     IQGDLENQISFRKALSDSLPNPTYVVNWQGNVISHNSAFEHYFTADYYKNAMLPLENS
                     DSPFKDVFSNAHEVTAETKENRTIYTQVFEIDNGIEKRCINHWHTLCNLPASDNAVYI
                     CGWQDITETRDLINALEVEKNKAIKATVAKSQFLATMSHEIRTPISSIMGFLELLSGS
                     GLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGNYQLQPQWVDIPTLVQNTCHS
                     FGAIAASKSIALSCSSTFPDHYLVKIDPQAFKQVLSNLLSNALKFTTEGAVKITTSLV
                     HIDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQTGSGLGLMICKELIKNM
                     QGDLSLESHPGIGTTFTITIPVEISQQVATVEAKAEHPITLPEKLSILIADDHPTNRL
                     LLKRQLNLLGYDVDEATDGVQALHKVSMQHYDLLITDVNMPNMDGFELTRKLREQNSS
                     LPIWGLTANAQANEREKGLSCGMNLCLFKPLTLDVLKTHLSQLHQVAHIAPQYRHLDI
                     EALKNNTANDLQLMQEILMTFQHETHKDLPAAFQALEAGDNRTFHQCIHRIHGAANIL
                     NLQKLINISHQLEITPVSDDSKPEILQLLNSVKEHIAELDQEIAVFCQKND"
     gene            complement(4380..5525)
                     /gene="yfdE"
                     /locus_tag="RN951_003998"
     CDS             complement(4380..5525)
                     /gene="yfdE"
                     /locus_tag="RN951_003998"
                     /EC_number="2.8.3.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416872.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA:oxalate CoA-transferase"
                     /protein_id="HDX2528920.1"
                     /translation="MTNNESKGPFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPP
                     GHGDDTRTFGPYVDGQSLYYSFINHGKESVVLDLKNDHDKSIFINMLKQADVLAENFR
                     PGTMEKLGFSWETLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYP
                     DAPPVRVGTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMA
                     YIATGKSPQRLGNRHPYMAPFDVFNTQDKPITICCGNDKLFSALCQALELTELVNDPR
                     FSSNILRVQNQAILKQYIERTLKTQAAEVWLARIHEVGVPVAPLLSVAEAIKLPQTQA
                     RNMLIEAGGIMMPGNPIKISGCADPHVMPGAATLDQHGEQIRQEFSS"
     gene            complement(5599..6543)
                     /gene="yfdV"
                     /locus_tag="RN951_003999"
     CDS             complement(5599..6543)
                     /gene="yfdV"
                     /locus_tag="RN951_003999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter YfdV"
                     /protein_id="HDX2528921.1"
                     /translation="MLTFFIGDLLPIIVIMLLGYFSGRRETFSEDQARAFNKLVLNYA
                     LPAALFVSITRANREMIFADTRLTLVSLVVIVGCFFFSWFGCYKFFKRTHAEAAVCAL
                     IAGSPTIGFLGFAVLDPIYGDSVSTGLVVAIISIIVNAITIPIGLYLLNPSSGADGKK
                     NSNLSALISAAKEPVVWAPVLATILVLVGVKIPAAWDPTFNLIAKANSGVAVFAAGLT
                     LAAHKFEFSAEIAYNTFLKLILMPLALLLVGMACHLNSEHLQMMVLAGALPPAFSGII
                     IASRFNVYTRTGTASLAVSVLGFVVTAPLWIYVSRLVS"
     gene            complement(6613..8307)
                     /gene="oxc"
                     /locus_tag="RN951_004000"
     CDS             complement(6613..8307)
                     /gene="oxc"
                     /locus_tag="RN951_004000"
                     /EC_number="4.1.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxalyl-CoA decarboxylase"
                     /protein_id="HDX2528922.1"
                     /translation="MSDQLQMTDGMHIIVEALKQNNIDTIYGVVGIPVTDMARHAQAE
                     GIRYIGFRHEQSAGYAAAASGFLTQKPGICLTVSAPGFLNGLTALANATVNGFPMIMI
                     SGSSDRAIVDLQQGDYEELDQMNAAKPYAKAAFRVNQPQDLGIALARAIRVSVSGRPG
                     GVYLDLPANVLAATMEKDEALTTIVKVENPSPALLPCPKSVTSAISLLAKAERPLIIL
                     GKGAAYSQADEQLREFIESTQIPFLPMSMAKGILEDTHPLSAAAARSFALANADVVML
                     VGARLNWLLAHGKKGWAADTQFIQLDIEPQEIDSNRPIAVPVVGDIASSMQGMLAELK
                     QNTFTTPLVWRDILNIHKQQNAQKMHEKLSTDTQPLNYFNALSAVRDVLRENQDIYLV
                     NEGANTLDNARNIIDMYKPRRRLDCGTWGVMGIGMGYAIGASVTSGSPVVAIEGDSAF
                     GFSGMEIETICRYNLPVTIVIFNNGGIYRGDGVDLSGAGAPSPTDLLHHARYDKLMDA
                     FRGVGYNVTTTDELRHALTTGIQSRKPTIINVVIDPAAGTESGHITKLNPKQVAGN"
     gene            complement(8361..9611)
                     /gene="frc"
                     /locus_tag="RN951_004001"
     CDS             complement(8361..9611)
                     /gene="frc"
                     /locus_tag="RN951_004001"
                     /EC_number="2.8.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formyl-CoA transferase"
                     /protein_id="HDX2528923.1"
                     /translation="MSTPLQGIKVLDFTGVQSGPSCTQMLAWFGADVIKIERPGVGDV
                     TRHQLRDIPDIDALYFTMLNSNKRSIELNTKTAEGKEVMEKLIREADILVENFHPGAI
                     DHMGFTWEHIQEINPRLIFGSIKGFDECSPYVNVKAYENVAQAAGGAASTTGFWDGPP
                     LVSAAALGDSNTGMHLLIGLLAALLHREKTGRGQRVTMSMQDAVLNLCRVKLRDQQRL
                     DKLGYLEEYPQYPNGTFGDAVPRGGNAGGGGQPGWILKCKGWETDPNAYIYFTIQEQN
                     WENTCKAIGKPEWITDPAYSTAHARQPHIFDIFAEIEKYTVTIDKHEAVAYLTQFDIP
                     CAPVLSMKEISLDPSLRQSGSVVEVEQPLRGKYLTVGCPMKFSAFTPDIKAAPLLGEH
                     TAAVLQELGYSDDEIAAMKQNHAI"
BASE COUNT         2846 a         2191 c         1989 g         2599 t
ORIGIN      
        1 atcttaaagg aagctcagat tttcttattt ttattgagaa aatgagatga cgccttatgt
       61 ctgtattact acagggagaa gggagatgct tcattgcaaa gggaataatc tatgaacgca
      121 ataattattg atgaccatcc tcttgctatc gcagcaattc gtaatttatt gatcaaaaac
      181 gatattgaaa tcttagcgga gttgactgaa gggggaagcg ccgttcagcg ggtggaaaca
      241 cttaagcctg atatcgtcat cattgatgtc gatatccccg gagttaacgg tatccaggtg
      301 ttagaaacgc tgaggaagcg ccaatatagc ggaattatta ttattgtctc cgctaaaaat
      361 gaccattttt acgggaaaca ttgtgctgat gctggcgcta atggattcgt gagtaaaaaa
      421 gaaggcatga acaatatcat tgcggctatt gaagctgcaa aaaatggcta ctgctatttc
      481 cccttctctc tcaaccggtt tgttggaagt ttaacgtccg accagcaaaa actcgactcc
      541 ttatcgaaac aagaaattag tgtcatgcgg tatattcttg atggcaagga taataatgac
      601 attgctgaaa aaatgttcat cagcaacaaa actgtcagca cttataaaag tcgcctgatg
      661 gaaaaattag aatgtaaatc actgatggat ctttacacat tcgcgcaacg taacaaaatc
      721 ggctaatcac atgaagtttt taccctattt ttttcttctc tgttgtggtc tttggtcgac
      781 cataagtttc gcagacgaag attacatcga atatcgtggc atcagtagta acaaccgtgt
      841 cacacttgat ccagtacgtc tgagcaacaa ggaattacgt tggttagcga gcaaaaaaaa
      901 tcttgtgatt gcagtacaca agtcccaaac ggctaccttg ttgcataccg attcgcagca
      961 acaggttcgt ggtattaatg ctgattattt aaatctttta aaaagagcgt taaatatcaa
     1021 attaacactc cgggaatacg cagatcatca aaaagcaatg gacgcgcttg cagaaggtga
     1081 agtcgatata gtgttatcac atttagttac ttcgccgcct cttaataatg acattgctgc
     1141 aaccaaacca ttgataatta cctttccggc gctggtaacc acccttcacg actcaatgcg
     1201 accgcttacc tcaccaaaac cagtaaatat tgctcgggta gcaaattacc ccccagacga
     1261 ggtaattcat caatcatttc caaaagcaac aattatctct tttacaaatt tatatcaggc
     1321 attagcatcc gtctcagctg ggcacaatga ttactttatt ggtagtaaca tcattaccag
     1381 cagtatgatt tcccgctatt tcactcactc cttaaatgta gtgaaatatt ataactcgcc
     1441 gcgtcaatat aattttttct tgaccagaaa agaatctgtc attcttaatg aagtactcaa
     1501 tagatttgtt gatgctttaa caaatgaagt tcgctatgaa gtatcacaaa attggcttga
     1561 tacaggaaac ctggcctttc tgaacaaacc attagaactc actgaacatg aaaaacagtg
     1621 gattaagcag catcccaatt taaaggtgct ggaaaatcct tactcgcccc cctattctat
     1681 gacggatgaa aatggctcgg ttcggggcgt tatgggggac attcttaata ttattacctt
     1741 gcaaacaggt ttaaattttt ctccgatcac cgtttcacac aatatccatg ctggaacaca
     1801 gcttagcccc ggaggatggg atataatacc tggcgctatt tatagtgaag atcgagaaaa
     1861 taatgtttta tttgctgaag ccttcataac aacgccttac gtttttgtca tgcaaaaagc
     1921 gcctgacagt gaacaaacat taaaaaaagg aatgaaagtt gccattccat attattatga
     1981 gctgcattcg caattaaaag agatgtatcc ggaggttgaa tggatacagg tcgataatgc
     2041 cagcgctgca tttcacaagg ttaaggaagg tgaacttgat gctctggtcg cgacacagtt
     2101 aaattcgcgt tacatgatcg atcattacta tcctaatgaa ctttatcatt ttcttattcc
     2161 tggcgttccg aatgcatcgc tttcgttcgc ttttcctcgc ggagaaccgg aacttaagga
     2221 tattattaat aaagcactga atgcaattcc cccaagcgaa gttctgcgcc tgacggaaaa
     2281 atggattaaa atgcccaatg tgaccattga cacatgggac ctatatagcg agcaatttta
     2341 tattgttacg acattatccg ttttattagt tggcagtagc cttttatggg gattctacct
     2401 gttacgctca gttcgtcgtc gtaaagtcat tcagggtgat ttagaaaacc aaatatcatt
     2461 ccgaaaagca ctctcggatt ccttaccgaa tccaacttat gttgtaaact ggcaaggtaa
     2521 tgtcattagt cataatagtg cttttgaaca ttatttcact gcggattact acaaaaatgc
     2581 aatgttacca ttagaaaaca gtgactcacc ctttaaagat gttttttcta atgcgcatga
     2641 agtcacagca gaaacgaaag aaaatcgaac aatatacaca caggtatttg aaattgataa
     2701 tggcatcgag aaaagatgca ttaatcactg gcatacatta tgcaatcttc ctgcaagtga
     2761 caatgcagta tatatttgtg gttggcaaga tattactgaa acgcgtgatc taattaatgc
     2821 actcgaggta gaaaaaaata aagcgataaa ggctaccgta gcaaaaagtc agtttctggc
     2881 aacgatgagt cacgaaataa gaacaccaat aagctctatt atgggcttcc tggaacttct
     2941 gtcgggttct ggtcttagca aggagcaacg ggtggaggcg atttcacttg cctacgccac
     3001 cggacaatca ctcctcggct taattggtga aatccttgat gtcgacaaaa ttgaatcggg
     3061 taactatcaa cttcaaccac aatgggtcga tatccctact ttagtccaga acacttgtca
     3121 ctctttcggt gcgattgctg caagcaaatc gatcgcatta agttgcagca gtacatttcc
     3181 tgatcattac ctggttaaga tcgaccctca ggcgtttaag caggtcttat caaatttact
     3241 gagcaatgct ctcaaattta ccaccgaggg ggcagtaaaa attacgacct ccctggttca
     3301 cattgatgac aaccacgctg ttatcaaaat gacgattatg gattctggaa gtggattatc
     3361 gcaggaagaa caacaacaac tctttaaacg ctacagccaa acaagtgcag gtcgccagca
     3421 aacaggatct ggcttaggct taatgatctg caaagaatta attaaaaata tgcagggcga
     3481 tttgtcatta gaaagtcatc caggcatagg aacaacattt acgatcacaa tcccggtaga
     3541 aattagccag caagtggcga ctgtcgaggc aaaagcagaa caccccatca cactacctga
     3601 aaagttgagc atattaatcg cggatgatca tccgaccaac aggctattac tcaaacgcca
     3661 gctaaatcta ttaggatatg atgttgatga agccactgat ggtgtgcaag cgctacacaa
     3721 agtcagtatg caacattatg atctgcttat tactgacgtt aatatgccga atatggatgg
     3781 ttttgagttg actcgcaaac tccgtgagca aaattcttcc ttacccatct gggggcttac
     3841 agccaacgca caggctaacg aacgtgaaaa agggttaagt tgcggcatga acttatgttt
     3901 gttcaaaccg ttgaccctgg atgtactgaa aacacattta agtcagttac accaggttgc
     3961 gcatattgca cctcagtatc gccaccttga tatcgaagcc ctgaaaaata atacggcgaa
     4021 cgatctacaa ctgatgcagg agattctcat gactttccag catgaaacgc ataaagatct
     4081 acccgctgcg tttcaagcac tagaagctgg cgataacaga actttccatc agtgtattca
     4141 tcgcatccac ggtgcggcta acatcctgaa tttgcaaaag ttgattaata ttagccatca
     4201 gttagaaata acacctgttt cagatgacag taagcctgaa attcttcagt tgctgaactc
     4261 tgtaaaagaa cacattgcag agctggacca ggagattgct gttttctgtc agaaaaatga
     4321 ctaaatagcg gctcccacaa tgttcaaatg tgggagctat ttaccagcac atcttacatt
     4381 tatgatgaga actcctggcg aatttgttcc ccatgctggt cgagcgttgc cgctcccggc
     4441 ataacatgcg ggtccgcgca gccgctgatt tttatcggat tacccggcat cattattccc
     4501 ccggcttcaa tcaacatatt tctcgcctga gtttgtggca atttaatggc ctcagccaca
     4561 cttaataacg gcgcgacggg tacaccaact tcatgtattc tggctaacca aacttcagct
     4621 gcctgcgttt ttaacgtccg ctcaatatat tgtttaagaa tagcctggtt ttgtacgcgt
     4681 aaaatattgc tgctaaatcg gggatcatta accagttccg taagctccag tgcctggcat
     4741 aacgcagaaa aaagcttgtc attaccacaa caaatcgtaa tcggcttatc ctgagtattg
     4801 aaaacatcaa aaggtgccat gtagggatgg cgatttccca gacgttgtgg tgacttccct
     4861 gtcgcgatat atgccatcag accatgctcc agaaaactca gcgtggcatc aaacatcgct
     4921 atatcgacat gcgcccctct ctggctcttt tcgcggccat aaagtgcact cactattccg
     4981 ctgaataaat agacaccgcc gcatagatcc gcaagagatg taccaacgcg cactggcgga
     5041 gcatcaggat atcctgtttc catcattatc ccgctcattg cctgaatgat ggtatcgtag
     5101 gcaggagcat cttttagcgg accggtatgt ccgaaacctg acgatgaagc atatatgagg
     5161 cgcgggttga tttcttgaag cgtttcccat gaaaacccca gtttttccat tgtacctggg
     5221 cgaaaattct cagctaatac atcagcttgt ttgagcatat ttataaatat acttttatcg
     5281 tgatcattct ttaaatcaag aaccacactc tctttgccat gattaataaa actgtaatag
     5341 agtgactgtc catccacata gggaccaaat gtgcgggtat catcaccatg acctggtggc
     5401 tcaactttaa ttacccttgc gcccatatta caaagaagtt gagttccgaa aggtccatta
     5461 aggacatgtg tcatatcgat aactaataag ccttcaaacg gccctttgct ttcattattt
     5521 gtcatttgct tatgccttga aaaaagccga aggtgaaaag acacttcggc atttatgtaa
     5581 aatcaataac atgattaatt atgaaaccag tcgactgaca taaatccaca agggagccgt
     5641 gacgacaaag cccagtacgc tcacagccaa tgacgctgta ccagtacggg tgtagacatt
     5701 aaaccggctg gcaataatga ttccggagaa tgccggcggt aatgcgcctg ccagtaccat
     5761 catctgcaga tgttcgctgt tcaaatgaca tgccatacca acgagaagca gtgccagtgg
     5821 catcagaatc agcttcagga aggtgttata agcaatttcg gcactgaact cgaatttatg
     5881 tgcagccaga gtcaaccccg cagcgaatac cgctacccct gagttagcct tcgcaatcag
     5941 attaaaggtt gggtcccatg ctgccggaat ttttacccca accaacacca ggatcgttgc
     6001 cagaacaggt gcccatacta ctggctcctt tgccgcagaa attaatgcgc tcagattact
     6061 attcttctta ccatccgctc ctgaggaagg attcagcaaa tacagaccaa taggaatagt
     6121 aattgcgtta acaataatag aaataattgc taccactaaa cctgttgata cggaatcacc
     6181 ataaatagga tcgagaactg caaaccccag gaatccaatg gtaggtgaac ctgcaattaa
     6241 tgcacataca gctgcttctg catgggtacg tttaaaaaat ttgtagcaac cgaaccagga
     6301 gaaaaagaaa catccgacaa taaccacaag tgatacaagg gtcagacgag tgtccgcaaa
     6361 aatcatttcc ctgtttgccc gagtaataga tacaaataga gccgcaggaa gcgcgtagtt
     6421 taataccagt ttattaaatg cccgagcttg atcttctgaa aatgtttctc gtctgccgct
     6481 aaaataaccc aacagcatga ttacgataat aggcaataaa tcgccaataa aaaatgttag
     6541 cataatagta tttccgataa gggtcccctc accatcgcat aatgagttgg caagaggaga
     6601 cgatgtcagt atttaattac cagcgacttg ttttgggtta agtttggtaa tatggccact
     6661 ttcagttcct gctgcagggt cgatgaccac attaataatg gtcggtttgc gcgactgaat
     6721 accggtggtt aaagcatgac gaagttcatc tgtcgtggtg acgttatagc caacgccacg
     6781 aaacgcatcc attaatttgt cataccttgc atggtgcaac agatccgttg gtgatggtgc
     6841 accagcgcca ctgagatcaa caccgtctcc tctgtagatg ccgccattat taaaaataac
     6901 gatcgtcacc ggcaggttat atcgacaaat cgtttcaatt tccatcccac tgaaaccaaa
     6961 agcactatca ccttcaatgg cgacaaccgg agaaccagaa gtcacgctag caccgatggc
     7021 atagcccata ccgatgccca tgacacccca ggtaccacaa tccagacgac gacgtggttt
     7081 atacatatca ataatatttc gtgcattatc cagggtattt gcaccttcat taactaaata
     7141 aatatcctgg ttctcgcgca atacgtcgcg cacagcactt aatgcattaa agtaatttaa
     7201 tggttgagta tctgtactta atttttcatg cattttttgt gcattttgct gcttgtggat
     7261 atttaaaata tcgcgccata ccagtggagt cgtaaatgtg ttttgtttca gttctgccag
     7321 cataccttgc atactggatg caatatcacc aacgactggc acagcaatgg ggcggttgct
     7381 gtcaatttcc tgcggttcaa tatccagttg aataaactgt gtatctgccg cccatccttt
     7441 tttaccgtgt gccaataacc aattcagtcg tgcaccaaca agcatgacaa cgtcagcatt
     7501 tgccagggca aacgaacgcg cagctgccgc agaaagtgga tgcgtatctt caaggatccc
     7561 tttcgccata gacattggca ggaatggaat ctgagtactt tcaataaatt cacgaagctg
     7621 ttcatcagct tgtgaatacg ccgcgccttt gccaaggata attaatggcc gttcagcttt
     7681 tgctaaaagc gaaattgcgc tagtgactga cttcgggcat ggcaataatg ctggcgatgg
     7741 attttcaact ttaacaatcg tggttaacgc ttcgtctttt tccatcgtcg cggccaggac
     7801 atttgctggc aaatcaagat aaactccgcc agggcgaccc gatacagaga cccggatagc
     7861 gcgtgccaat gcaatgccaa gatcctgcgg ctgattaacg cgaaatgctg ctttggcata
     7921 cggttttgcc gcattcattt ggtccagctc ttcataatca ccttgctgta ggtcgacgat
     7981 cgcgcggtcg ctggagccgc taatcatgat catcggaaaa ccatttaccg ttgcgttggc
     8041 caatgcggtc aaaccattga ggaatcctgg cgcagaaact gtcaggcaga tccccggttt
     8101 ttgggtaaga aaaccgcttg ccgcagcggc atagcctgcc gactgctcat gacgaaaacc
     8161 aatataacga atgccttccg cctgggcatg gcgtgccata tccgtcacag gaatacctac
     8221 aacaccataa atagtgtcaa tattattctg ttttaatgct tcaacgatga tatgcatacc
     8281 atctgtcatt tgaagttgat ctgacatgat taataacctc gaaattttta taaattggga
     8341 gccagaagcc cccgttaata tcagatggcg tggttttgct tcattgcagc aatttcatcg
     8401 tcgctataac ctagctcctg caatacagca gcggtatgtt cacctaatag cggcgcagct
     8461 ttaatatccg gcgtaaaggc agagaatttc attggacaac caacggtcag atattttcca
     8521 cgcaacggtt gttccacttc aacaacactg ccactttggc gcaaagaggg atcaagtgaa
     8581 atttctttca tacttaaaac cggtgcacaa ggaatatcaa actgagtcaa ataggccacc
     8641 gcttcatgtt tatcaatagt gacagtgtat ttttcgattt cagcaaaaat atcgaaaata
     8701 tgtggctgtc gtgcatgggc tgtactgtat gccggatcgg taatccattc tggtttgccg
     8761 atggctttac aggtgttttc ccagttttgc tcctgaatag tgaaataaat ataggcgtta
     8821 ggatcggttt cccagccttt acatttcagg atccagccag gctgaccgcc accacctgca
     8881 ttaccaccgc ggggaactgc atcaccaaat gtaccattcg gatactgcgg gtattcttcc
     8941 agataaccca atttatcgag acgctgctgg tcacgtaatt tcacgcggca aaggttcaat
     9001 acggcatcct gcattgacat ggtgactcgt tgcccacgcc ccgttttttc gcgatgcagc
     9061 aaagcagcaa gtaaaccgat cagcaaatgc attccggtgt tgctgtcacc caacgctgca
     9121 gcgcttacca gcggcggacc atcccaaaaa cccgtagtgg atgccgcgcc acccgctgcc
     9181 tgagcaacgt tttcataggc ttttacattc acataaggcg aacactcatc aaaccctttg
     9241 atcgaaccaa aaatcagacg tggattgatt tcttgaatat gctcccaggt gaagcccatg
     9301 tgatcaatgg cccctggatg aaagttctcg actaagatat cagcttcgcg gatcagcttt
     9361 tccattacct ctttgccttc cgctgttttg gtatttaact caatagaacg tttgttactg
     9421 ttaagcatgg tgaagtaaag cgcatcgata tcaggaatat ctcgcagctg gtgacgcgtt
     9481 acgtcaccaa cgccgggacg ttcaatttta ataacgtcag cgccaaacca ggccagcatt
     9541 tgagtacaag atgggccaga ttgcacaccg gtgaaatcga gaactttaat tccttgaagt
     9601 ggagttgaca tagcaatacc tatta
//
LOCUS       DAPOAV010000128         9585 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.128, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000128 DAPOAV010000000
VERSION     DAPOAV010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9585
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.128"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(64..822)
                     /locus_tag="RN951_004002"
     CDS             complement(64..822)
                     /locus_tag="RN951_004002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDX2528924.1"
                     /translation="MSQILLQPANAMITLENVNKWYGQFHVLKNINLTVQPGERIVLC
                     GPSGSGKSTTIRCINHLEEHQQGRIVVDGIELNEDIRNIERVRQEVGMVFQHFNLFPH
                     LTVLQNCTLAPIWVRKMPKKEAEALAMHYLERVRIAEHAHKFPGQISGGQQQRVAIAR
                     SLCMKPKIMLFDEPTSALDPEMVKEVLDTMIGLAQSGMTMLCVTHEMGFARTVADRVI
                     FMDRGEIVEQAAPDEFFAHPKSERTRAFLSQVIH"
     gene            complement(830..1933)
                     /locus_tag="RN951_004003"
     CDS             complement(830..1933)
                     /locus_tag="RN951_004003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709065.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDX2528925.1"
                     /translation="MTKVLLSHPPRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWL
                     MWELIPPLLNWAFLQANWVGSTRADCTKAGACWVFIHERFGQFMYGLYPHDQRWRINL
                     ALLIGLVSIAPMFWKILPHRGRYIAAWAVIYPLIVWWLMYGGFFGLERVETRQWGGLT
                     LTLIIASVGIAGALPWGILLALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVML
                     PLFMAEGTSIDKLIRALVGVILFQSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQ
                     GLVILPQALKLVIPGLVNTIIALFKDTSLVIIIGLFDLFSSVQQATVDPTWLGMSTEG
                     YVFAALIYWIFCFSMSRYSQHLEKRFNTGRTPH"
     gene            complement(1943..3124)
                     /locus_tag="RN951_004004"
     CDS             complement(1943..3124)
                     /locus_tag="RN951_004004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDX2528926.1"
                     /translation="MSHRRSTVKGSLSFANPTVRAWLFQILAVVAVVGIVGWLFHNTV
                     TNLNNRGITSGFAFLDRGAGFGIVQHLIDYQQGDTYGRVFIVGLLNTLLVSALCIVFA
                     SVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSA
                     FDLAFLSNRGLYIPSPQLGDGFIAFILAVVMAIVLSVGLFRFNKTYQIKTGQLRRTWP
                     IAAVLIIGLPLLAQWLFGAALHWDVPALRGFNFRGGMVLIPELAALTLALSVYTSAFI
                     AEIIRAGIQAVPYGQHEAARSLGLPNPVTLRQVIIPQALRVIIPPLTSQYLNIVKNSS
                     LAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVE
                     R"
     gene            complement(3192..4217)
                     /locus_tag="RN951_004005"
     CDS             complement(3192..4217)
                     /locus_tag="RN951_004005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDX2528927.1"
                     /translation="MKKMMIATLAAASVLLAVANQAHAGATLDAVQKKGFVQCGISDG
                     LPGFSYADADGKFSGIDVDICRGVAAAVFGDDTKVKYTPLTAKERFTALQSGEVDLLS
                     RNTTWTSSRDAGMGMAFTGVTYYDGIGFLTHDKAGLKSAKELDGATVCIQAGTDTELN
                     VADYFKANNMKYTPVTFDRSDESAKALESGRCDTLASDQSQLYALRIKLSNPAEWIVL
                     PEVISKEPLGPVVRRGDDEWFSIVRWTLFAMLNAEEMGINSQNVDEKAANPATPDMAH
                     LLGKEGDYGKDLKLDNKWAYNIIKQVGNYSEIFERNVGSESPLKIKRGQNNLWNNGGI
                     QYAPPVR"
     gene            complement(4648..4869)
                     /locus_tag="RN951_004006"
     CDS             complement(4648..4869)
                     /locus_tag="RN951_004006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528928.1"
                     /translation="MKRLIPVALLTALLAGCAHDSPCVPVYDDQGRLVHTNTCMKGTT
                     QDNWETAGAIAGGAAAVAGLTMGIIALSK"
     gene            complement(5122..8226)
                     /gene="acrF"
                     /locus_tag="RN951_004007"
     CDS             complement(5122..8226)
                     /gene="acrF"
                     /locus_tag="RN951_004007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit AcrF"
                     /protein_id="HDX2528929.1"
                     /translation="MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVS
                     VSANYPGADAQTVQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDI
                     AQVQVQNKLQLATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVAS
                     NVKDTLSRLNGVGDVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQ
                     LGGTPALPGQQLNASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYN
                     VIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQ
                     LSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLS
                     AVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENK
                     GGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEE
                     DQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAG
                     MAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFE
                     LIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGV
                     SLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMV
                     PFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGY
                     DWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLA
                     ATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLR
                     PILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR
                     CFKG"
     gene            complement(8238..9395)
                     /gene="acrE"
                     /locus_tag="RN951_004008"
     CDS             complement(8238..9395)
                     /gene="acrE"
                     /locus_tag="RN951_004008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrE"
                     /protein_id="HDX2528930.1"
                     /translation="MTKHARFFLLPSFILISAALIAGCNDKGEEKAHVGEPQVTVHIV
                     KTAPLEVKTELPGRTNAYRIAEVRPQVSGIVLNRNFTEGSDVQAGQSLYQIDPATYQA
                     NYDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAK
                     ATVESARINLAYTKVTAPISGRIGKSTVTEGALVTNGQTTELATVQQLDPIYVDVTQS
                     SNDFMRLKQSVEQGNLHKENATSNVELVMENGQTYPLKGTLQFSDVTVDESTGSITLR
                     AVFPNPQHTLLPGMFVRARIDEGVQPDAILIPQQGVSRTPRGDATVLIVNDKSQVEAR
                     PVVASQAIGDKWLISEGLKSGDQVIVSGLQKARPGEQVKATTDTPADTASK"
BASE COUNT         2541 a         2488 c         2296 g         2260 t
ORIGIN      
        1 catcaaatca agcgaaaggc catccgaaag gatggccttt ttgcttttcg aactaacatt
       61 caattaatgg attacctgcg ataaaaatgc cctcgtacgc tctgatttag gatgcgcaaa
      121 aaattcatca ggtgcagctt gttccactat ctccccacga tccataaaaa ttacccggtc
      181 agcgacggta cgtgcaaacc ccatctcatg tgttacacac aacattgtca tacccgactg
      241 cgccagccca atcatcgtat ccagcacctc tttcaccatc tccggatcga gcgccgacgt
      301 tggctcatca aacaacataa ttttcggctt catacacagc gaacgcgcaa tggcaacgcg
      361 ttgctgctga ccaccagaaa tttgtccggg aaacttatgc gcatgttcgg caattctcac
      421 ccgctcaagg taatgcatcg ccagagcttc agcctctttc tttggcatct tgcgtaccca
      481 aatcggtgcc agggtacagt tctgtagaac ggtcagatga gggaagagat tgaaatgctg
      541 aaagaccatt cccacttcct gccggacgcg ctcaatattg cggatatctt cattaagttc
      601 gatgccatct accacgatcc gtccctgttg atgttcttcc agatgattaa tacaacgaat
      661 ggttgtcgat ttaccggaac ctgaagggcc acacagaacg atccgttctc ccggttgcac
      721 ggttaaattt atatttttca aaacatggaa ttgtccatac catttattga cgttttccag
      781 cgtaatcatc gcgttagcag gttgcagtaa aatttggctc atagtgtcct caatgcggtg
      841 tacgcccggt gttaaaacgt ttttccagat gctggctata gcgcgacatg ctgaaacaga
      901 agatccagta gatcagcgcg gcgaaaacat acccttccgt cgacataccc aaccaggtgg
      961 gatcaacggt tgcctgctga acgctactga aaagatcgaa caacccgata atgatcacca
     1021 ggctggtatc tttgaagagt gcgatgatgg tatttaccag cccaggaatt accagcttca
     1081 acgcctgtgg cagaataacc agcccctgag ttttccagta acccaacgcc agcgactctg
     1141 ccgcttcata ctgcccttta ggcagtgcct gtaatccgcc tcgcacgact tccgcaacat
     1201 atgctgactg aaacaggatc acgccaacca gcgcgcggat cagtttgtcg atactggtgc
     1261 cttctgccat aaacaacggc agcatgaccg aagacataaa caatacggta atcagcggta
     1321 cgccgcgcca gaactcgata aaaatgaccg ataagatacg cacaatcggc atatgggagc
     1381 ggcgacctaa cgccagtaag atcccccacg gtagcgcccc cgcaatccca acggatgcaa
     1441 taattaaagt tagcgtcagc ccgccccatt gccgggtttc aacccgctcc agaccaaaaa
     1501 aaccgccata catcagccac cagacaatca gtgggtaaat caccgcccag gccgcaatat
     1561 agcgaccgcg atgcgggagt attttccaga acattggtgc gatcgacaca agcccaatca
     1621 gtaatgcgag gttaattcgc cagcgttggt cgtgtgggta aagcccatac ataaactgac
     1681 caaatcgttc gtggatgaag acccaacagg caccggcttt tgtgcagtcg gcacgcgttg
     1741 agccaaccca gttagcctgc aaaaatgccc agttcagcaa cggtgggatc agttcccaca
     1801 tcaaccatat gcagccaata gtcagcaggc tattgctcca gctggagaac agattttttc
     1861 gcacccacac catcgcgcgg cttgagttat ggctcgccgg gcgcggggga tgagacagca
     1921 atacttttgt catcatgact ccttagcgtt caacgatcgc gatgcggcgg ttatagatat
     1981 tcatcagcag cgagatagtc aggctgataa tcagatagac cgacatggtc atggctatcg
     2041 tctcgatggc ttgccccgtc tgattcagca cggtgccggc aaacagcgaa accatatcgg
     2101 gatagccaat agcggcggca agagaggagt ttttgacgat gttgagatac tggctggtta
     2161 acggtggaat aatcacccgc aatgcctggg gaataatgac ctggcgtagc gtaaccgggt
     2221 tgggtaatcc cagtgaccga gccgcttcat gttgaccata aggcactgcc tggatcccag
     2281 cgcggataat ctcggcgata aatgcagatg tataaaccga aagtgccagc gttaaggctg
     2341 ccagttcagg aattaaaacc atcccgccgc ggaagttaaa gcctcgtagg gctgggacat
     2401 cccagtgtag tgctgcgcca aaaagccatt gcgccagtaa aggcaaacca atgatcaaca
     2461 ctgcggcgat cggccaggtg cggcgcagtt gtccggtctt tatctggtat gttttattaa
     2521 agcggaatag cccaacagaa aggactatag ccataacaac agccaggata aacgcaataa
     2581 atccgtctcc cagctgcggt gacggaatat aaagcccacg attgctcaaa aaggccagat
     2641 caaacgcgct cacagcctgg cgtggtccgg gcaaattgcg caacacggca aagtaccaga
     2701 agaagatttg cagcagcggg ggaatattac ggaagatctc aatataaatt gtggaaagct
     2761 ttcgtagcag ccagttatcc gaaagtctcg ccagaccgat aaagaagccc aaaacagaag
     2821 cgaacacaat acacaatgca gaaaccagta gcgtattgag taagccgaca ataaaaacgc
     2881 gtccgtaggt gtcgccctgc tggtaatcga tcaaatgctg gacaataccg aagccagcgc
     2941 cgcgatccag aaaggcaaaa cctgaagtaa tgccacgatt attgagattc gttacagtgt
     3001 tgtgaaataa ccaaccaaca atgccgacaa cagcaacaac ggcaaggatc tggaataacc
     3061 aggcgcgaac cgtagggttg gcaaaagaga gtgagccttt aacggttgag cggcgatgag
     3121 acatagaaac ctcggaaagc ataacgctga agagagcgcc gccgtagcga cgctcgttac
     3181 ctcacaccga cttaacgcac gggcggtgcg tactgaatac cgccgttatt ccagagatta
     3241 ttttgcccac gtttaatttt cagcgggctt tctgaaccta cgttacgctc aaaaatttcc
     3301 gagtagttac ccacctgttt gatgatgtta taggcccatt tattatccag cttcagatcc
     3361 ttgccgtaat cgccttcttt acccagcaga tgtgccatat caggcgttgc tggattagcc
     3421 gctttttcat cgacgttctg ggaattgatg cccatctctt cagcattcag catggcgaaa
     3481 agcgtccagc gtacaatcga gaaccattca tcatcgccac gacgaactac cggaccaagc
     3541 ggttcttttg agataacttc cggtaagaca atccattcag ctgggttgct taatttgatg
     3601 cgcagggcat acagttgtga ttgatccgag gccagcgtat cgcagcgacc agattccagt
     3661 gccttcgctg attcgtcaga gcgatcgaaa gtcaccggtg tgtacttcat attgtttgcc
     3721 ttgaagtagt cggcgacgtt gagttcggta tcagtacccg cctgaataca gacggtagcg
     3781 ccatccagtt ctttcgcgct ttttagcccc gctttatcgt gcgtcaggaa gccaatgccg
     3841 tcgtaataag tgacgccggt aaatgccatt cccatcccgg catcgcgaga tgaagtccag
     3901 gtcgtattac gggagagcaa atccacctcc cctgactgta aagcggtgaa gcgttctttt
     3961 gcagtgagcg gggtatattt cactttcgtg tcgtcaccaa atacagcagc ggcaacacca
     4021 cgacaaatat caacatcaat acctgaaaac ttaccgtcag catcggcata agagaaccca
     4081 ggtaatccat cactgatccc gcattgcaca aaaccttttt tctgaacggc atcaagcgtc
     4141 gcgccagcat gcgcctgatt tgcaacggca agcagcacgc tggcggcagc cagtgtggct
     4201 atcatcatct ttttcataat gcttcctgtg aggcgaaaat tatcgttata ggacgtttgg
     4261 gaaacgtctt ttacctgtct gtggccatcc tcttataagc aaaagtagtg ccagcttttg
     4321 cgcacgattt cgcgtcgcaa taagctgagt gtagacagga aataataaaa acagcgcccc
     4381 gcaatggtgc gaaaatgaaa catgcgccac attttggcgc aaaatattta cgcgtgtttt
     4441 actaagcaga ataatgattg ttagcgtgag tatatttctg gtgggaagtg tgaaaattaa
     4501 attgatgcgt tatttcgaaa gcagcgaaat aacgcgatgt aacatgctaa atcagcaggg
     4561 aattacccag cagaatatag caatatttta tcttatggag agatactgta tcgttaaaaa
     4621 gagcgcggaa ctccgcgccc tgttcagtta tttcgataga gcgatgatcc ccatcgtcag
     4681 gccagcaaca gcagctgccc cgccggcaat agccccagcc gtttcccagt tatcctgagt
     4741 cgtgcctttc atacaggtat tggtgtgaac cagacgaccc tgatcgtcat aaaccggaac
     4801 gcagggcgaa tcgtgagcac agcccgccag caatgcggtg agcaatgcca caggaattaa
     4861 tcttttcatg gtgttacctc agtaataaac gctaacgctt aataagttaa ctctcttatt
     4921 aacgagctga atgccatttt atcaccggag gttataaatc ttgcggaatg aataatgaca
     4981 aattatgtga attgtaaaag tagtgaaggg agcgggaact atagaaagct tttaaagagt
     5041 gagcagaaga atatcttatt aatttttatg ggtttcactg gaaataataa aggcacccga
     5101 aagcgccttt atgtttctga tttatccttt aaagcaacgg cggatcacca caaagaacac
     5161 cggtacgaag aagattgcca gcaacgttgc agagaccatt cctcccatta ccccgatacc
     5221 cacagcgttc tgcgcgccac tgccggcacc gttactgata gctagcggta atacgccgag
     5281 aataaaggcg agagaggtca tcaggatagg acgcagacgc atacgtactg ccatcagtgt
     5341 cgcttcaaca acacctttac cctctttctc catgagatct ttagcgaact caacgatcaa
     5401 aatagcgttt ttggccgaca agccaattgt cgttagcaag cccaccataa agtagacgtc
     5461 atttttttga ttaaagagtg tcgccgccag cagcacgccg acaatcccta acggcactac
     5521 caacataacc gagacaggaa ttgaccagct ttcatagagt gcagcaaggc acaggaaaac
     5581 aaccacaaag gaaattgcta ccagagcggg agcctggttt cccgataagc gttcctgata
     5641 cgacataccc gtccagtcat aaccaatgcc cgcaggtaat tttgacgcaa ggttttccat
     5701 caacgccatg gcatcgccgg aactggttcc tggcgcggct tccccctgaa tctccattga
     5761 cggcagaccg ttgtagcgtt ccagtcgcgg agagccatac acccaatgtg aagtggtaaa
     5821 ggccgagaat ggcaccattt cgccgttggc gctgcggaca taaagtttat cgacatcttc
     5881 tggcagcata cggaatttgg catccgcctg aacatacaac tttttcacgc gaccacggtc
     5941 gatgaagtcg ttaacgtaag tcccacccag cgccgttgaa atggtctgat tgatgtcaga
     6001 aagtgaaaca cctaatgcct gcgccttttc ctggtcaact tccagtttaa actgcgcggt
     6061 gtcttccagg ccattagggc gcacgctgac taagctggca ggatgttgcg ccgccatacc
     6121 aagcaactgg ttacgggcct gggttagggc atcgtgaccc agcccagcct gatcaattaa
     6181 ctcaaagtcg aaacccgttg ccgtgcccag ttcaacaatg gctggcatat tgaatggaat
     6241 gacaaaaccg tcgcggatct tgcccaattc cattttggca cgatggatta ccgcttccgc
     6301 actgttttcg tcaccattac gctcttccca cggtttcaga ctgacgaagg ccataccggc
     6361 gttttgtgcc tggccgctga agctaaagcc gttaaccgta aagacacttt caacgttcgc
     6421 tttctcgttc ttcagatagt aatccgtaac ttgatccaac actttttgcg tccgctcttg
     6481 cgtcgcgcca gcgggtaact gaatcatggt cagaaagaca ccctgatcct cttcaggtaa
     6541 gaaggaagac ggaagacgta aaaacaacac caccattcct gcaacaatca gcgcatagat
     6601 cagtaaatat cgtcctgtgg atccgaggat tttgccgacg ctgttggtgt agtggttaac
     6661 gctatgatcg aaggtggtat taaaccaacc gaagaaaccg cccttatttt cgtgatgctc
     6721 agcagagacg ggtttaagca gcgttgcaca taacgcaggg gtaagaatca atgccaccag
     6781 aacagaaagc gccattgccg aaacgatggt gatagagaac tggcgataaa ttgccccagt
     6841 agaaccgccg aagaatgcca tcggaataaa taccgctgac agcaccatcg cgatacccac
     6901 cagtgcgccc tgaatttgcg acatcgattt ttccgtcgct tcttttggcg ggagcttatc
     6961 ctccatcatc acgcgctcga cgttctccac caccactatc gcatcatcga cgagcagccc
     7021 gatggcaagc accatcccga acatcgttag tgtgttgatg gagtaaccaa aagcggcgag
     7081 gatggcaaac gtccctaaca acaccacggg taccgcaatg gtggggatca gcgttgctcg
     7141 catattctgc aagaacagat acatcaccag gaacaccagc ataatggctt cgaacagcgt
     7201 ttttaccact tcgtgaatag aaagctggac gaatggcgtg gtgtcataag ggtagagaac
     7261 cttcattccc tgcgggaaga atggctgtaa ttccgccagt tttgccttaa tggctttcgc
     7321 ggtatcgaga gcattcgcgc cggttgccag cttaatcccc aggcccgccg ccggttttcc
     7381 gttgatacga gcgataacgt tatagttttc accgccaagt tcaacccgtg cgacatcttt
     7441 caggcgtacc accgagccgt cactgtttac gcgcagggtc actttgccga attcttccgg
     7501 atttttaaac cgcgtctgag caataatcga ggcgttcaat tgttgccctg gtaacgctgg
     7561 cgttccgccc aactgtccgg cagcgatctg atcgttctgt accttcaact ggttaatcac
     7621 atcaaccggt gtcagtttat atttgtttag cagatcggca tccagccaga tacgcatcgc
     7681 atactgtgcg ccgaaaagct gtacgtcacc gacgccattc agacggctaa gcgtatcttt
     7741 aacgttagag gccacatagt ccgagatatc gtcctgtgtg gtgcctgggt tatcagagac
     7801 aaagcccgcc accatcaaat agctgctact ggacttttca acactgatcc cctgctgctg
     7861 aacctcctgc ggcagcaacg gcgtggcgag ctggagtttg ttctgcacct gcacttgcgc
     7921 gatatcagga tcggtcccgg actggaaggt aagggtaatt gtcacgctac cggcggaatc
     7981 gctggtggag gacatataca tcaggttatc gataccgttc atattctgtt cgataacctg
     8041 cgtcaccgta tcctgcacgg tctgcgcatc agcgcccgga tagtttgctg aaacagaaac
     8101 cgcaggcggt gcaattgttg gatactgagc gacgggcaat tgtaggatcg ccagtgcgcc
     8161 cgccatcatc agaataatgg ccagcaccca tgcaaatatc ggtcgtcgaa taaaaaagtt
     8221 tgccatgtca gattacctta cttcgatgca gtatctgcgg gggtatcggt agtggcttta
     8281 acctgctctc ccgggcgcgc tttttgcagg ccgctgacaa tgacttgatc gccagatttc
     8341 agtccttcac taatcaacca tttatcgcca atcgcctgac tggcaacgac agggcgcgct
     8401 tcaacctgac ttttatcgtt aacaatcagc acggttgcat caccacgcgg tgtgcggcta
     8461 acgccttgtt gcgggataag aatggcgtca ggttggacgc cttcatcaat ccgtgcgcgc
     8521 acaaacatac ccggcaaaag cgtatgttgc gggttaggga agacggcacg tagggttatg
     8581 gagccggtgc tttcatcaac ggtcacatca gagaattgca gcgtaccttt caggggatag
     8641 gtttgaccgt tttccatgac caactctacg ttgctggtgg cgttttcctt atgcaaattt
     8701 ccttgctcta cggattgctt cagcctcata aaatcgttgc tggattgggt cacatcaacg
     8761 tagataggat cgagctgctg gacagtcgcc agttcagtcg tttgcccatt agtgacaaga
     8821 gcgccttcgg tcacggtcga tttgccgata cgtccgctaa ttggcgcagt cactttggta
     8881 taagcgagat tgatgcgagc gctttcgact gtggcttttg cggcaatcac ggcggcatcg
     8941 gcctggcgag catcagcaat ggcctggtcg tactcctgct ggctgatgta tttcgtaccc
     9001 acgagcggaa cgtaacgttt taccgtcaaa tgcgcgatgg cggcggcggc ttcacttttc
     9061 gccagttcgc ctttcgcgct gtcataattt gcctgatagg tcgcgggatc gatctggtac
     9121 agggactggc ctgcttgtac atcgctgcct tcagtgaaat tacgattcag tacgatcccg
     9181 ctaacctgtg ggcgaacttc ggctatacgg taagcattgg tgcggcctgg taattcagtc
     9241 ttaacttcta acggggccgt tttcacaata tgaacggtaa cctgcggttc accgacgtga
     9301 gctttctctt ctcccttatc gttacaaccg gcgattaaag ccgcggagat cagaataaag
     9361 gagggcagga ggaaaaacct ggcatgtttc gtcattacta ttcctcaaaa aaccaaaagc
     9421 gcgttattta cccagaaagg caacgcgtta actcgcagaa agaaaaatac agtttgctat
     9481 cctacaaatt atcattcgtc gatgtaagga atagttatga atactggcgt ctcaaggcac
     9541 ataaacacaa aaaaagatta atattctact gttttatttt gacgc
//
LOCUS       DAPOAV010000129         9469 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.129, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000129 DAPOAV010000000
VERSION     DAPOAV010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9469
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.129"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(57..542)
                     /locus_tag="RN951_004009"
     CDS             complement(57..542)
                     /locus_tag="RN951_004009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface exclusion protein"
                     /protein_id="HDX2528931.1"
                     /translation="MIMRCLTHITLVTVIQFIACYLASWGNAETIFMLFFIVLWQGLF
                     IWLFSQIRKKRNVSDEFKFSKGVWYITMPVSSLLSPLLSLMVFIIGTLYELRRVSGCV
                     SVREWMQSQVNEQTNEDLHLDFDNMDFHRTNPATGLPMSGIGVDIGGNSYGYSSKRYD
                     E"
     gene            complement(558..3380)
                     /gene="traG"
                     /locus_tag="RN951_004010"
     CDS             complement(558..3380)
                     /gene="traG"
                     /locus_tag="RN951_004010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer mating pair stabilization
                     protein TraG"
                     /protein_id="HDX2528932.1"
                     /translation="MNEVYVIAGGEWLRNNLNAIAAFMGTRTWDSIEKIALTLSVLAV
                     AVMWVQRHNVMDLLGWVAVFVLISLLVNVRTSVQIIDNSDLVQVHRVDNVPVGLAMPL
                     SLTTRIGHAMVASYEMIFTQPDSATYSKTGMLFGANLIVKSTDFLSRNPEIINLFQDY
                     VQNCVLGDIYLNHKYTLEDLMASADPYTLIFSRPSPLRGVYDSNNNFITCKDASVTLK
                     DRLNLDTKTGGKTWHYYVQQIFGGRPDPDLLFRQLVSDSYSYFYGSSQSASHIMRQNV
                     TMNALKEGITSNAARNGDTASLVSLATTSSMEKQRLAHVSIGHVLMRNLPMVQTILVG
                     ITIGIFPLLVLAAVFNRLTLSVLRGYVFALMWFQTWPLLYAILNSAMTFYAKQNGAPV
                     VLSELSQIQLKYSDLASTAGYISVMIPPLSWMMVKGLGAGFSSVYSHFASSAISPTAS
                     AAGSVVDGNYSYGNMQTENVNGFSWSTNSTTSFGQMMYQTGSGATATQTRDGNMVMDA
                     SGAMSRLPVGINATRQIAAAQQEMAREASNRAESALHGFSSSIASAWNSLSQFGSNRG
                     SSDSVTGGADSTMSAQDSMMASRMRSAVESYAKAHNISNEQATQELASRSTRASAGMY
                     GDAHAEWGVKPKILGVGGGLGVRGGGRAGIDWEDNDAHTASSNTQSSHNARHDIDARA
                     TQDFKEASDYFTSRKVSESGSHTDNNADSRVDQLSAALNSAKQSYDQYTTNMTRSHEY
                     AEMASRTESMSGQMSEDLSQQFAQYVMKHAPQDAEAILTNTSSPEIAERRRAMAWSFV
                     QEQVQPGVDNAWRESRGDIGKGMESVPSGGGSQDIIADHQGHQAIIDQRTQDSNIRND
                     VKHQVDNMVTEYKGNIGDTQNSVRGEENIVRGQYSELQNHHKTEALSQNNKYNEEKSA
                     QERMPGADSPQELMKRAKEYQDKYKQ"
     gene            complement(3377..4750)
                     /locus_tag="RN951_004011"
     CDS             complement(3377..4750)
                     /locus_tag="RN951_004011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraH"
                     /protein_id="HDX2528933.1"
                     /translation="MLRIKPLLVLCAALLTVTPAASADVNSDMNQFFNKLGFASNTTQ
                     PGVWQGQAAGYAYGGSLYARTQVKNIQLISMTLPDINAGCGGIDAYLGSFSFINGDQL
                     QRFVKQIMSNAAGYFFDLALQATVPEIKTAKDFLQKMASDINSMNLSSCQVAQGIVGG
                     LFPQTQVSQQKVCQDIAGESNIFADWAASRQGCTVGGQSSSVRDKASDKDKERVLKNI
                     NIIWDSLSKNRMLDGNKELKEFIMTLTGTLIFGEDSEITPLPARTTDRDILRAIMEGG
                     TAKVYHCNDSDKCLKVVADANVTIARDKALKSQITKLLTSIQNKAVSDTPLDDREKGF
                     ISSTTVPVFKYLIDPQMLGVSSSVVYQLTDYIGYDIMLQYIQELLQQARAMIATGNYP
                     QTVLDSVLENLNQAQQQIAVFQGQVKVQQDALLVVDRQMSYMRQQLSARMLSRYQNNY
                     HFGGSTL"
     gene            complement(4737..5162)
                     /gene="trbF"
                     /locus_tag="RN951_004012"
     CDS             complement(4737..5162)
                     /gene="trbF"
                     /locus_tag="RN951_004012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001323332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F-type conjugal transfer protein TrbF"
                     /protein_id="HDX2528934.1"
                     /translation="MNHRKYQRKLIMKEKRNDAELKNRKTKRDYDYERRVSDIYFDLF
                     FVFVAAGTFLWVIMHSIFDACIDSWKADPELNNFRYMWNILMYVIPYTLWAFAGGFLI
                     VYVRNPLNELINGGIRIFRLKRRMRREKKLREGGNNASH"
     gene            complement(5110..5457)
                     /gene="trbJ"
                     /locus_tag="RN951_004013"
     CDS             complement(5110..5457)
                     /gene="trbJ"
                     /locus_tag="RN951_004013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001444236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein TrbJ"
                     /protein_id="HDX2528935.1"
                     /translation="MPPVLWRGWIPFCRCTERKKVRNKQVVLLIAGISGIATGIIVSL
                     NIPFIRQGLFYPASPVEIVVSLCLTFSVSVVFFVGAIVGWISVSEIYYSRMNGLNESS
                     EISEETYNERKKK"
     gene            complement(5387..5932)
                     /gene="trbB"
                     /locus_tag="RN951_004014"
     CDS             complement(5387..5932)
                     /gene="trbB"
                     /locus_tag="RN951_004014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000052622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly thiol-disulfide isomerase TrbB"
                     /protein_id="HDX2528936.1"
                     /translation="MSLTKLLPVILLMMATGVQASTRDEIERLWNPQGMAVQPAQPAA
                     DTSARTEKPAPRWFRLSNGRQVNLADWKVVLFMQGHCPYCHQFDPVLKQLAQQYGFSV
                     FPYTLDGQGDTAFPEALPVPPDVMQTFFPNIPVATPTTFLVNVNTLEALPLLQGATDA
                     ASFMARMDTVLQMYGEEKGTK"
     gene            complement(5919..6203)
                     /gene="traQ"
                     /locus_tag="RN951_004015"
     CDS             complement(5919..6203)
                     /gene="traQ"
                     /locus_tag="RN951_004015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001617873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     chaperone TraQ"
                     /protein_id="HDX2528937.1"
                     /translation="MISKYRFSLPRLDITGMWVFSLGVWFHIVARLVYSKPWMAFFLA
                     ELIAAILVLFGAYQVLDAWIARVSLEEREALEARQQAMMEGQQEGGHVSH"
     gene            complement(6322..6666)
                     /gene="trbA"
                     /locus_tag="RN951_004016"
     CDS             complement(6322..6666)
                     /gene="trbA"
                     /locus_tag="RN951_004016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016230911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbA"
                     /protein_id="HDX2528938.1"
                     /translation="MHTGDLCFFTGASLFIVGVVGYFFTGPNNKGVYLLSSFVFFVVN
                     VISVCMLPDNFLFLCGAVMNQCAVPVVSMAVSTIPVITKFDSFRRMFVCIMLSSAWSG
                     VMWFFIRGLMTG"
     gene            complement(6680..7423)
                     /gene="traF"
                     /locus_tag="RN951_004017"
     CDS             complement(6680..7423)
                     /gene="traF"
                     /locus_tag="RN951_004017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly protein TraF"
                     /protein_id="HDX2528939.1"
                     /translation="MNKALLPLLLCCFIFPASGKDAGWQWYNEKINPKEKENKPVPAA
                     PRQEPDIMQKLAALQTATKRALYEAILYPGVDNFVKYFRLQNYWTQQAGLFTMSAKKA
                     MLAHPELDYNLQYSHYNGTVRNQLAADQAQQRQAIAKLAEHYGIMFFYRGQDPIDGQL
                     AQVINGFRDTYGLSVIPVSVDGVINPLLPDSRTDQGQAQRLGVKYFPAMMLVDPKQGS
                     VRPLSYGFISQDDLAKQFLNVSEDFKPNF"
     gene            complement(7416..7673)
                     /gene="trbE"
                     /locus_tag="RN951_004018"
     CDS             complement(7416..7673)
                     /gene="trbE"
                     /locus_tag="RN951_004018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbE"
                     /protein_id="HDX2528940.1"
                     /translation="MKVIFTSNRLVDFLIRLSITAIVISPVIIWSWDTVKETTADGML
                     AAAFVILYSGVLLFILYFCFSALTGLQKDDERKNDERNEDE"
     gene            complement(7700..>9469)
                     /gene="traN"
                     /locus_tag="RN951_004019"
     CDS             complement(7700..>9469)
                     /gene="traN"
                     /locus_tag="RN951_004019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system mating-pair
                     stabilization protein TraN"
                     /protein_id="HDX2528941.1"
                     /translation="SDFARQIQGQGTGSIQGFKPQESIPSYNANPDETKYYGGVTAGG
                     DGGLKNDGTTEWATGETGKTITESFMNKPKDILSPDAPFIQTGRDVVNRADSIVGNTG
                     QQCSAQEINRSEFTNYTCERDTMVEEYCTRTASITGDWKYTDEYREVTIPHSQFRFSM
                     NGLKLVFSVTAPVTGTVESASLSVYAAFFFLNSRYTFMNTTFNVGLANGQSDTYPLSG
                     ATGLQVTQGQVLTGSGCTANGNCLPHGNGDRKVYESLVSGASTFTLKLRMKVRDKEWV
                     PRVEWVESCPFNKADGVLTGTECSEPGGTKTGVMEGKPWNITQACWAYRDKYVTQSAD
                     NGTCQKYVDNPACTLASRQCAFYSDEGTCLHEYATYSCESRTSGKVMVCGGDVFCLDG
                     ECDKAQSGKSSDFGEAVSQLAALAAAGKDVAALNGVDVRAFTGEAKFCRKAAAGFSNC
                     CKDGGWGQDVGLAKCNSEEKALGKAKDNKLTVSVGEFCSKKVLGVCLQKKRSYCQFDS
                     KLAQIVQQQGRNGQLRIGFGSAKHPDCRGITVDELQKIQFDRLDFTNFYEDLMNNQKI
                     PDSGVLTQKVKEQIADQLKQAGQ"
BASE COUNT         2352 a         2601 c         2088 g         2428 t
ORIGIN      
        1 attttcatca atgttccttc atattgaata aaacgtcata atatacaaat taagattcac
       61 tcatcatatc gttttgaact ataaccatat gaattaccac cgatatccac accaatacct
      121 gacataggta accctgttgc aggattagta cgatgaaaat ccatattatc aaaatccaga
      181 tgcaaatctt cattagtttg ttcatttacc tgagattgca tccattctct tacgcttaca
      241 caaccactaa ctcgccttaa ttcgtatagt gtaccaatga taaaaaccat caggcttaat
      301 aatggagaga gtaaggaaga tactggcatc gttatatacc aaacgccttt actaaactta
      361 aactcatccg acacattccg tttttttcgt atttgagaga acaaccatat aaacagtccc
      421 tgccatagta ctatgaagaa cagcataaaa attgtttcgg cattccccca actagccaga
      481 taacaggcga taaactgtat caccgttacc agagtaatat gggttaaaca tctcattatc
      541 atctcccaaa aacagcatta ttgcttatac ttatcctgat attcctttgc ccttttcatc
      601 agttcctgtg gactgtcagc cccgggcatt ctttcctgag ccgacttttc ttcattatat
      661 ttattattct gagataatgc ctctgtttta tggtgattct gcagttcaga atactgtcct
      721 cttacaatat tttcctcgcc acgtacgctg ttctgagtat cacctatatt ccctttatat
      781 tctgtgacca tattatcaac ctgatgtttt acatcattac ggatattact gtcctgcgtt
      841 ctttgatcaa taatggcctg atgcccctga tggtcagcaa taatatcctg actgccacca
      901 cccgaaggta cgctctccat tcctttacca atatcaccac gggattcccg ccaggcatta
      961 tcaacaccag gctgtacctg ttcctgcaca aaagaccagg ccatcgcccg acgacgttct
     1021 gcaatctccg gtgaactggt gtttgtcaga atagcttctg catcctgtgg cgcgtgtttc
     1081 attacatact gtgcaaactg ttgcgacagg tcttcactca tctgcccact catgctttca
     1141 gtacgggatg ccatttcagc atattcatgg ctgcgggtca tattcgtcgt gtactggtcg
     1201 taactctgct tcgctgaatt cagggctgca gacaactgat ccacacggga atcagcatta
     1261 ttgtccgtat ggctgccgga ctcactgacc ttgcgactgg taaaataatc gctggcctct
     1321 ttaaagtctt gtgtagctct ggcatcgata tcatgacgag cattatggct cgactgagta
     1381 ttactacttg ccgtatgcgc atcattatct tcccaatcaa taccagcccg accaccacct
     1441 ctaacgccta atcctccacc aacaccaaga attttaggtt taacccccca ttcagcatga
     1501 gcatctccat acatcccggc agaagctctc gtacttctgg atgccagttc ctgagtcgcc
     1561 tgctcattac tgatattatg cgccttcgca tagctttcca ctgcactgcg catacggctg
     1621 gccatcatgg agtcctgtgc gctcatcgtg ctgtcagcac cacctgtgac agaatcactg
     1681 ctcccccggt tagaaccaaa ctggctgagc gagttccagg cactggcaat actgctgctg
     1741 aacccatgca gggcgctttc tgctctgttc gacgcctccc gggccatttc ctgttgtgcc
     1801 gctgcaatct gacgcgttgc attgataccg accggtaacc gggacatcgc cccgctcgca
     1861 tccatcacca tattaccgtc acgggtctgt gtggcagttg cgccactgcc ggtctggtac
     1921 atcatctgac caaacgacgt ggtgctgttg gtgctccagc tgaagccgtt cacgttttcc
     1981 gtctgcatgt tgccgtagga gtaattaccg tcaaccacac tacctgccgc actggcagtc
     2041 gggctgatag cagaggaagc gaaatggctg tacacgctgg aaaaacctgc gccaaggcct
     2101 tttaccatca tccatgacaa cgggggtatc atgacagata tatatccggc agtggacgcc
     2161 aggtcggagt atttcagctg tatctgagag agttcagaga gcacgaccgg tgcaccattc
     2221 tgctttgcat agaatgtcat ggcactgttc agaatggcat acagcaacgg ccaggtctgg
     2281 aaccacatca gagcaaacac atagcctctc agaacagaca gcgtcagtct gttgaagaca
     2341 gccgccagta ccaggagcgg gaagatacca atggtaatgc ccaccagaat ggtctgcacc
     2401 atcggcaggt ttcgcatcag cacatgacca atggagacat gtgccagacg ctgtttctcc
     2461 atcgacgaag tcgtggccag actgaccagg ctggcggtat caccgttacg ggctgcatta
     2521 ctggtgatac cctctttcag ggcattcatg gtgacgttct ggcgcataat atgactggca
     2581 gactggctgg agccgtagaa ataactgtaa ctgtcactca ccagttgcct gaataacagg
     2641 tccgggtccg gtctgccgcc aaatatctgc tgcacataat aatgccaggt cttgcctccc
     2701 gtctttgtat cgagattcag cctgtctttc agcgtgaccg acgcatcttt acaggttatg
     2761 aaattattat tgctgtcata aacgccccgt agcgggctgg gccgggaaaa aatcagcgtg
     2821 taggggtcag cggaggccat caggtcttcc agcgtgtatt tgtggttcag gtaaatatcc
     2881 cccagcacgc agttctggac gtagtcctga aacagattga tgatttccgg attccgggac
     2941 agaaaatcgg tgcttttcac aatcaggttc gccccgaaca gcatgcctgt cttgctgtag
     3001 gtggcgctgt caggctgggt gaatatcatc tcgtaactgg ccaccattgc atgcccgata
     3061 cgggtcgtca gtgaaagtgg catcgccagt ccgacaggca cattatccac ccggtgaacc
     3121 tggaccaggt cactgttatc aataatctgc accgatgtac ggacattaac cagcaggctg
     3181 ataagcacaa acacggccac ccagcccagc aaatccatca cgttgtgccg ctgtacccac
     3241 atcacggcca ccgcgagaac agacaatgtg agcgcaattt tttcgatgga atcccacgtc
     3301 cgggtcccca taaaggcggc aatggcgttc aggttattgc gtaaccactc accaccggca
     3361 atcacataga cttcattcac agcgtgctcc ctccgaagtg atagttgttc tggtaacggc
     3421 tgagcatgcg ggcggaaagc tgctggcgca tatagctcat ctgacggtca acaaccagca
     3481 atgcatcctg ctggaccttt acctgcccct ggaaaaccgc aatctgttgc tgtgcctgat
     3541 tcagattctc cagcacactg tccagcacgg tctgtggata gttcccggtg gcaatcatgg
     3601 cccgggcctg ctgaagcagt tcctgaatgt actggagcat gatgtcgtag ccgatatagt
     3661 ccgtcagctg gtaaaccacg ctgctggata caccgagcat ctgcgggtca ataagatatt
     3721 taaagacggg gacggtggtg ctggaaatga agcctttttc cctgtcatcc agtggagtat
     3781 cactcaccgc tttattctga atactggtga gcagttttgt aatctgtgat ttcagggctt
     3841 tatcccgggc gatggtcaca tttgcatccg ccaccacctt cagacacttg tccgaatcgt
     3901 tgcagtgata aacttttgcc gttcccccct ccataatcgc ccggaggata tcgcggtcag
     3961 tggtacgcgc cggcaggggg gtaatctcgc tgtcttcccc aaaaatcagc gtaccggtga
     4021 gcgtcataat aaattctttc agttctttgt taccatcaag catcctgttt ttggacagcg
     4081 agtcccagat gatattgatg ttcttcagca cccgttcctt atctttgtca ctggccttgt
     4141 cacgaacaga cgatgactgt cctccgaccg tgcagccctg acgggacgcg gcccagtcag
     4201 caaaaatatt gctctcaccg gcaatgtcct gacagacctt ctgctgtgac acctgagtct
     4261 gaggaaataa tcctccgaca atcccctgcg ccacctgaca ggagctgagg ttcatactgt
     4321 taatgtcgct tgccattttc tgcaggaagt cttttgcggt tttgatttcc ggcaccgttg
     4381 cctgcagggc aaggtcaaaa aagtaaccgg cagcgttgct cataatctgc ttaacaaaac
     4441 gctgcaactg atcgccatta ataaaactga acgagccgag ataggcgtcg atgccgccac
     4501 atccggcatt gatatccggc agcgtcatgg aaatcagctg gatatttttg acctgggtgc
     4561 gggcatacag ggagccacca taggcatacc cggcggcctg cccctgccag acgcccggtt
     4621 gtgtggtatt ggaagcaaat cccagcttat taaagaactg attcatgtcg ctgttcacat
     4681 ccgctgacgc tgcgggtgtg accgtcagta aagcggcaca aagaaccaga agaggtttaa
     4741 tgcgaagcat tattgccacc ctcccttaat ttcttctccc ggcgcatacg gcgtttcagc
     4801 cggaatattc tgatcccccc gtttattaat tcatttaaag ggttcctgac gtatacgata
     4861 agaaatccac ctgcaaacgc ccataacgta tacggaatga catacatcag gatgttccac
     4921 atataacgaa aattatttaa ttccgggtca gctttccacg aatcaataca ggcatcaaaa
     4981 atactatgca taatcaccca taaaaaagtt ccggcagcaa cgaacacaaa aaacagatca
     5041 aaatatatat cagaaaccct gcgttcataa tcataatccc gtttagtttt tctgtttttt
     5101 agttccgcat catttctttt ttctttcatt ataagtttcc tctgatattt ccgatgattc
     5161 attcagaccg ttcatgcggc tgtaatatat ttcagacacc gaaatccatc ccacaattgc
     5221 ccccacaaaa aacacaacag aaacagaaaa ggtaagacac agcgaaacga caatttccac
     5281 agggctggcg ggataaaaaa gcccctgacg gataaagggg atattcaggc tgacgattat
     5341 tcccgtcgcg atgccggata ttccggcaat gagtaacacc acctgcttat ttcgtacctt
     5401 tttcctctcc gtacatctgc agaacggtat ccatccgcgc cataaaactg gcggcatccg
     5461 ttgccccctg caaaagcggt aatgcctcaa gtgtgttgac gttgaccagg aaggtagtcg
     5521 gtgtggccac cgggatattc gggaagaagg tctgcatcac gtccggtggc accggtaatg
     5581 cttccggaaa ggcggtatcc ccctgaccat ccagggtgta gggaaaaacg gaaaagccgt
     5641 actgctgtgc cagctgtttc agtaccgggt caaactggtg acagtaaggg caatgcccct
     5701 gcataaacag caccaccttc cagtcggcca ggttaacctg cctgccgttg ctgaggcgga
     5761 accagcgggg agccggcttt tctgttctgg ctgatgtgtc tgctgccggt tgtgcaggct
     5821 gcacggccat accctgcgga ttccagagtc gttcaatttc atcccgggtg gaggcctgca
     5881 cacctgtggc catcatcaac aaaatgaccg gcagtaattt agtgagagac atgtccgccc
     5941 tcctgctgcc cttccatcat ggcctgttgc ctggcttcca gtgcctcacg ctcttccagg
     6001 ctgacacgtg caatccatgc atccagcacc tggtatgcgc cgaacagcac aaggatggcc
     6061 gcaatcaact ccgccagaaa aaaagccatc cagggtttgc tgtaaacaag acgggcgacg
     6121 atatgaaacc agacacccag ggaaaatacc cacattcccg taatatcaag ccggggtaaa
     6181 gagaatctgt atttacttat catgttaaac tccggttatt atttacatga gagtattcat
     6241 gtctgtaata ttcgcgtttg tgtgatatta atcagatcaa cctcattatt ttgtatggtt
     6301 tttattaccg ttttatatga cttagcctgt cataagcccc cttataaaaa accacatcac
     6361 tccggaccat gctgatgaca acataataca aacaaacatc cttctgaaac tgtcaaactt
     6421 cgtgataacc ggtatggtac tgactgccat tgaaacaacc ggtacggcac actgattcat
     6481 aaccgcacca caaagaaaca agaaattatc tggcagcata catacactta tgacatttac
     6541 tacaaagaag acaaacgagc tcagcagata aactccttta ttatttggtc ctgtaaagaa
     6601 ataaccaaca acccccacga taaacaggct ggcacctgta aaaaaacaca aatcccctgt
     6661 atgcatatat aacctttggt taaaaattcg gtttaaaatc ttcagaaacg ttcaggaact
     6721 gttttgccag gtcgtcctgt gaaataaagc cgtatgataa cgggcgaaca ctgccctgtt
     6781 tcgggtcaac cagcatcatg gccgggaaat atttcacacc gaggcgctgc gcctgcccct
     6841 ggtcagtccg ggaatccggc aacagcggat taatcacgcc atccacggaa acgggaataa
     6901 cactcagacc ataggtatcc ctgaagccat taatgacctg cgccagttgc ccgtcgatgg
     6961 ggtcctgccc ccggtaaaag aacatgatgc cgtagtgttc agccagtttc gcaatggcct
     7021 gtcgctgctg cgcctggtct gccgccagct ggttccgtac cgtgccgttg taatggctgt
     7081 actgcaggtt atagtccagt tcgggatgtg ccagcatggc ctttttagca ctcatggtga
     7141 aaagcccggc ctgctgagtc cagtaattct gcagccggaa atatttaaca aaattatcca
     7201 cgccgggata cagaatggct tcgtacagcg cccgctttgt tgccgtctgc agcgcggcca
     7261 gtttctgcat aatatccggc tcctgacggg gggctgcagg tacaggttta ttttcttttt
     7321 ccttcggatt tattttctcg ttataccact gccagcctgc atctttccct gacgccggaa
     7381 aaataaagca gcagagtaac agtggcagta atgctttatt catcttcatt cctttcatca
     7441 ttttttcttt catcatcttt ctgcaggcca gtcagggcag aaaaacaaaa atacagaata
     7501 aacaggagca caccggagta aaggataacg aaagcagcgg caagcatccc gtctgccgtg
     7561 gtttctttta ccgtatccca cgaccagata attaccgggg aaatgacaat cgctgtaatc
     7621 gaaagccgga taagaaaatc aacaagacga ttagaagtga atataacttt catcatttcc
     7681 cccggttatt ttccatacct tactgtcctg cctgtttcag ctggtcagca atctgctctt
     7741 tcactttctg cgtcagaacg ccactgtccg ggattttctg gttattcatc aggtcttcgt
     7801 agaagttagt gaaatccagt ctgtcgaact gaattttctg cagctcatca accgtaatcc
     7861 cccgacagtc aggatgcttc gcactgccaa acccgatacg caactgcccg ttacgcccct
     7921 gctgctggac tatctgcgcc agcttcgaat caaactggca gtagctgcgc tttttctgca
     7981 gacagacacc cagcactttc ttcgaacaga actctccgac actgacggtc agtttgttgt
     8041 cctttgcctt tcccagcgcc ttttcttcgc tgttgcactt cgccagaccc acatcctgac
     8101 cccagccacc atccttacag cagttactga agccggctgc ggccttacgg cagaatttcg
     8161 cctcacccgt gaaagccctg acatccacac cattcagggc ggcaacatcc ttacctgcgg
     8221 cggcaagcgc agccagctgt gatactgctt caccaaaatc actgcttttt ccgctctgtg
     8281 ccttatcgca ttcaccgtca aggcagaaga catcaccacc acagaccatc acttttcctg
     8341 atgttctgga ctcgcaggag tacgtggcgt actcatgcag acaggttccc tcatcggaat
     8401 aaaacgcgca ctgacgtgag gccagcgtac aggccggatt atcgacatat ttctgacagg
     8461 tgccgttatc tgcggactga gtgacatatt tatcccggta tgcccagcat gcctgtgtga
     8521 tgttccaggg tttaccttcc atcactccgg ttttcgtacc acccggctct gaacactcag
     8581 tgcctgtcag cacgccatcc gctttattaa acggacaact ctccacccac tccacccggg
     8641 gaacccattc tttatcacgg accttcatcc tgagtttcag cgtaaaggtg gaagcaccac
     8701 tgacaagcga ttcatagact ttcctgtcac cattcccgtg cgggaggcaa ttaccgttag
     8761 cagtacagcc actaccggtc agaacctgcc cctgtgtcac ctgcaaacct gtcgccccgg
     8821 acagggggta agtatccgac tgcccgtttg ccaggccgac attaaaggtt gtattcatga
     8881 aggtataacg ggagttcagg aagaaaaaag cggcgtatac agacaatgat gcactttcca
     8941 ctgtaccggt taccggagcc gtgacactga acaccagttt cagcccgttc atactgaacc
     9001 ggaactgtga gtgcggtatc gtcacttcac gatattcatc cgtgtatttc cagtccccgg
     9061 tgatactggc agtccgtgtg cagtactcct ccaccatcgt gtcccgctca caggtatagt
     9121 ttgtgaattc actgcggttt atctcctgcg cactgcactg ctgtccggta tttcccacaa
     9181 tgctgtcagc ccggttcacc acatccctgc cggtctgaat gaacggtgca tccggtgaca
     9241 gaatgtcttt cggcttgttc atgaaggact ctgtgatggt ttttccggtt tcaccggtcg
     9301 cccattccgt ggtgccgtca tttttcaggc cgccatcccc gccggcagtc acgccaccgt
     9361 aatattttgt ctcgtccgga ttcgcgttat agctggggat actctcctgt ggcttaaagc
     9421 cctgaatact gcctgtaccc tgcccctgaa tctgacgggc aaaatcaga
//
LOCUS       DAPOAV010000130         9458 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.130, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000130 DAPOAV010000000
VERSION     DAPOAV010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9458
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.130"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..305)
                     /locus_tag="RN951_004020"
     CDS             complement(<1..305)
                     /locus_tag="RN951_004020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003898910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraS"
                     /protein_id="HDX2528942.1"
                     /translation="MITHYDIKMEMQKLKEVLSVEGVNIPSLLQVIKPGTYVFLWVLL
                     WPTFLRLVSVKSDVRDVGFDICASGMMGFLLFVAITNGMMLYLAIPDSFRKDSKIIN"
     gene            complement(302..3127)
                     /gene="traG"
                     /locus_tag="RN951_004021"
     CDS             complement(302..3127)
                     /gene="traG"
                     /locus_tag="RN951_004021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer mating pair stabilization
                     protein TraG"
                     /protein_id="HDX2528943.1"
                     /translation="MNEVYVIAGGEWLRNNLNAIAAFMGTRTWDSIEKIALTLSVVAV
                     AFMWVQRHNVMDLLGWAAVFVLISLLVNIRTSVQIIDNSDLVKVHRVDNVPVGLAMPL
                     SLTTRIGHAMVASYEMIYTQPDSFTYSKTGMLFGAELVSKSTDFLSRNPEIANLFQDY
                     VQNCVMGDIYLNHKYTLEELMASNDPYTLIFSRPSPLRGVYDSNNNFVTCKDASVSLK
                     DKLNLDTQSGGKTWHYYAQQLFGGRPDPNLLFSTLIGDSYRYFYDSSKSASQIIRQNV
                     TINALKEGITSYAARNGDSASLVNLATTSSMEKQRLAHVSIGHVAMRTLPMTQTILTG
                     IAIGIFPLLVLAAVFNKLTLSVLKGYVFALMWLQSWPMLYAILNSAMTFYAKQNGAPV
                     VLSEISQIQLKYSDLASTAGYLSMMIPPLSWMMVRGLGAGFSSVYSHFASSAISPTAS
                     AAGSVVDGNYSYGNMQTENVNGFSWSTNSTTSFGQMMYQTGSGATTTQTRDGNMVMDA
                     SGAMSRLPVGINATRQIAAAQQEMAREASNRAESALHGFSSSIASAWNSLSQFGSNRG
                     SSDSVTGGADSTMSAQDSMMASRMRSAVESYAKAHNISNEQATQELASTSTRLSGGMY
                     ADAHAEWGVKPKILGVGGGVGIRGGFKGSLDATDDDSHSASSGSRATHDARHDIDARA
                     TQDFKEASDYFTSRKVSESGSHTDNNADSRVDQLSAALNSAKQSYDQYTTNMTRSHEY
                     AEMASRTESMSGQMSEDLSQQFAQYVMKHAPQDAEAILTNTSSPEIAERRRAMAWSFV
                     QEQVQPGVDNAWRESRGDIGKGMESVPSGGGSQDIIADHQGHQAIIDQRTQDSNIRND
                     VKHQVDNMVTEYKGNIGDTQNSIHGEENIVDRQYSELKNNHKQEEIQQNNRYNEENKR
                     QKLIPTPSEDALKQMVDDKKERLKGPL"
     gene            complement(3124..4497)
                     /locus_tag="RN951_004022"
     CDS             complement(3124..4497)
                     /locus_tag="RN951_004022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraH"
                     /protein_id="HDX2528944.1"
                     /translation="MPRIKPLLVLCAALLTVTPAASADVNSDMNQFFNKLGFASNTTQ
                     PGVWQGQAAGYAYGGSLYARTQVKNVHLISMTLPDINAGCGGIDAYLGSFSFINSEQL
                     QRFVKQIMSNAAGYFFDLALQTTVPEIKTAKDFLQKMASDINSMNLSSCQAAQGIIGG
                     LFPRTQVSQQKVCQDIAGESNIFADWAASRQGCTVGGKSDSVRDKASDKDKERVTKNI
                     NIMWNALSKNRMFDGNKELKEFVMTLTGSLVFGPNGEITPLSARTTDRSIIRAMMEGG
                     TAKIYHCNDSDKCLKVVADTPVTISRDNALKSQITKLLASIQNKAVSDTPLDDKEKGF
                     ISSTTIPVFKYLVDPQMLGVSNSMIYQLTDYIGYDILLQYIQELIQQARAMVATGNYD
                     EAVIEHINDNMNDATRQIAAFQSQVQVQQDALLVVDRQMSYMRQQLSARMLSRYQNNY
                     HFGGSTL"
     gene            complement(4484..4876)
                     /gene="trbF"
                     /locus_tag="RN951_004023"
     CDS             complement(4484..4876)
                     /gene="trbF"
                     /locus_tag="RN951_004023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F-type conjugal transfer protein TrbF"
                     /protein_id="HDX2528945.1"
                     /translation="MTKNKKNQEFKIRKIRRNIEYSFRGSDRYFYLFIVFLVAGIVLW
                     AVMHVIFDVCIDSWMADPKLLNFQYMWNVLMKVIPFTLWALAARFLVTFFLSPMCELI
                     FGNIMIFLLKRRMRRENTLREGKNDATH"
     gene            complement(4830..5204)
                     /gene="trbJ"
                     /locus_tag="RN951_004024"
     CDS             complement(4830..5204)
                     /gene="trbJ"
                     /locus_tag="RN951_004024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001444236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein TrbJ"
                     /protein_id="HDX2528946.1"
                     /translation="MPPVLWRGWIPFCRCTEGKKVRNKQVVLLIAGISGIATGIIVSL
                     NIPFIRQGLFYPASPVEIVVSLCLTFSVSVVFFVGAIVGWISVSEIYYSRMTGLNESS
                     VISEETYNDKKQKESGIQNQKN"
     gene            complement(5134..5688)
                     /gene="trbB"
                     /locus_tag="RN951_004025"
     CDS             complement(5134..5688)
                     /gene="trbB"
                     /locus_tag="RN951_004025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000052622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly thiol-disulfide isomerase TrbB"
                     /protein_id="HDX2528947.1"
                     /translation="MSLTKLLPVILLMMATGVQASTRDEIERLWHPQGMAAQPAQPAA
                     DTPARTDKTEKPAPRWFRLSNGRQVNLADWKVVLFMQGHCPYCHQFDPVLKQLAQQYG
                     FSVFPYTLDGQGDMAFPEALPVPPDVMQTFFPNIPVATPTTFLVNVNTLEALPLLQGA
                     TDAAGFMARMDTVLQMYGGKKGAK"
     gene            complement(5675..5959)
                     /gene="traQ"
                     /locus_tag="RN951_004026"
     CDS             complement(5675..5959)
                     /gene="traQ"
                     /locus_tag="RN951_004026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001617873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     chaperone TraQ"
                     /protein_id="HDX2528948.1"
                     /translation="MISKRRFSLPRLDITGMWVFSLGVWFHIVARLVHSKPWMAFFLA
                     ELIAAILVLFGAYQVLDAWIARVSREEREALEARQQAMMAEQQEGGHVSH"
     gene            6040..6375
                     /locus_tag="RN951_004027"
     CDS             6040..6375
                     /locus_tag="RN951_004027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin ArtA"
                     /protein_id="HDX2528949.1"
                     /translation="MEKRSFKEKLEIVRNIIRESLSGNAAFALLVYSLLHTLPIKTFA
                     DLFVTILLFIAIIAVVIWLFLIIYVYFCDLFRSHWIAVWFILWSVVINLTIGFGIYDK
                     LAPVISLMK"
     gene            complement(6356..6697)
                     /gene="trbA"
                     /locus_tag="RN951_004028"
     CDS             complement(6356..6697)
                     /gene="trbA"
                     /locus_tag="RN951_004028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001530454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbA"
                     /protein_id="HDX2528950.1"
                     /translation="MHTGDLCFFTGASLFIVGVVGYFFTGLNNKGVYLLSSFVFFVVN
                     VISVCMLPDNFLFLCGAVMNQCAVPVVSMAVSTMPIITKFDSFRRMFICIMLSAIWSG
                     VMWFFIISLVK"
     gene            complement(6711..7454)
                     /gene="traF"
                     /locus_tag="RN951_004029"
     CDS             complement(6711..7454)
                     /gene="traF"
                     /locus_tag="RN951_004029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly protein TraF"
                     /protein_id="HDX2528951.1"
                     /translation="MNKALLPLLLCCFIFPASGKDAGWQWYNEKINPKEKENKPVPAA
                     PRQEPDIMQKLAALQTATKRALYEAILYPGVDNFVKYFRLQNYWTQQAGLFTMSARKA
                     MLAHPELDYNLQYSHYNGTVRNQLAADQAQQRQAIAKLAEHYGIMFFYRGQDPIDGQL
                     AQVINGFRDTYGLSVIPVSVDGVINPLLPDSRTDQGQAQRLGVKYFPAMMLVDPKQGS
                     VRPLSYGFISQDDLAKQFLNVSEDFKPNF"
     gene            complement(7447..7704)
                     /gene="trbE"
                     /locus_tag="RN951_004030"
     CDS             complement(7447..7704)
                     /gene="trbE"
                     /locus_tag="RN951_004030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbE"
                     /protein_id="HDX2528952.1"
                     /translation="MKVIFTSNRFIDFLIRLLITAIVISLVIIWSWDTVKETTADGML
                     AAAFVILYSGVLLFILYFCFSALTDLQKPDERKSDERNEDE"
     gene            complement(7731..>9458)
                     /gene="traN"
                     /locus_tag="RN951_004031"
     CDS             complement(7731..>9458)
                     /gene="traN"
                     /locus_tag="RN951_004031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001756807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system mating-pair
                     stabilization protein TraN"
                     /protein_id="HDX2528953.1"
                     /translation="SDFAHQIKGQGSSSIQGFKPQESIPGYNANPDETKYYGGVTAGG
                     DGGLKNDGTTEWATGETGKTITESFMNKPKDILSPDAPFIQTGRDVVNRADSIVGNTG
                     QQCSAQEISRSEYTNYTCERDLQVEQYCTRTARMELQGSTTWETRTLEYEMSQLPARE
                     VNGQYVVSITSPVTGEIVDAHYSWSRTYLQKSVPMTITVLGTPLSWNAKYSADASFTP
                     VQKTLTAGVAFTSSHPVRVGNTKFKRHTAMKLRLVVRVKKASYTPYVVWSESCPFSKE
                     LGKLTKTECTEAGGNRTLVKDGQSYSMYQSCWAYRDTYVTQSADKGTCQTYTDNPACT
                     LVSHQCAFYSEEGACLHEYATYSCESKTSGKVMVCGGDVFCLDGECDKAQSGQSNDFA
                     EAVSQLAALAAAGKDVAALNGVDVRAFTGQAKFCKKAAAGYSNCCKDSGWGQDIGLAK
                     CSSDEKALAKAKSNKLTVSVGEFCSKKVLGVCLEKKRSYCQFDSKLAQIVQQQGRNGQ
                     LRISFGSAKHPDCRGITVDELQKIQFNRLDFTNFYEDLMNNQKIPDSGVLTQKVKEQI
                     ADQLKQAGQ"
BASE COUNT         2332 a         2510 c         2123 g         2493 t
ORIGIN      
        1 aaatttatta tttttgaatc ctttctgaaa ctatcaggaa tcgcaaggta taacatcatt
       61 ccatttgtaa tagccacaaa aagcaggaac cccatcattc cactagcaca tatatcaaag
      121 ccaacatccc tgacatcact tttaaccgat actaaacgca gaaaagttgg ccataataaa
      181 acccataaaa acacataagt tcccggcttt atgacttgta ataatgatgg gatattaaca
      241 ccctctacag agagtacctc ctttagtttt tgcatctcca tttttatatc atagtgagtg
      301 atcataatgg ccccttcaat cgttctttct tatcatccac catctgtttt aacgcatctt
      361 cagacggtgt tggtattaat ttctgtcgtt tattttcttc attatatctg ttgttttgtt
      421 gaatttcttc ctgtttgtga ttatttttta actctgaata ttgtctgtct acaatatttt
      481 cttcgccatg aatactattc tgagtatctc cgatattccc tttatattct gtgaccatat
      541 tatcaacctg atgttttaca tcattacgga tattactgtc ctgcgttctt tgatcaataa
      601 tggcctgatg cccctgatgg tcagcaataa tatcctggct gccaccaccc gaaggtacgc
      661 tctccattcc tttaccaata tccccacggg attcacgcca ggcattatca acaccaggct
      721 gcacctgttc ctgaacaaaa gaccatgcca tcgcccgacg gcgttctgca atctccggtg
      781 aactggtgtt tgtcagaata gcttcggcat cctgcggtgc gtgtttcatc acatactgtg
      841 caaactgttg cgacagatct tcactcatct gcccactcat gctttcagta cgggatgcca
      901 tttcagcata ttcatggctg cgggtcatat tcgtcgtgta ctgatcgtaa ctctgtttcg
      961 ctgaattcag ggctgcagac agctggtcca cacgggaatc agcattattg tcagtatggc
     1021 tgccggattc actgactttg cgactggtaa agtaatcgct ggcctcttta aagtcttgtg
     1081 tagctctggc atcgatatca tggcgagcat catgggtagc cctgctgcca ctacttgctg
     1141 aatgtgagtc atcatccgtt gcatccaagc tccccttaaa tccacctctg atgcctaccc
     1201 caccaccaac accaagaatt ttaggtttaa ccccccattc agcatgagca tcagcataca
     1261 ttccaccaga tagcctggta cttgttgatg ccagttcctg agtcgcctgc tcattactga
     1321 tattatgcgc cttcgcatag ctttccactg cactgcgcat acggctggcc atcatggaat
     1381 cctgtgcgct catcgtgctg tcagcaccac ctgtgacaga atcactgctc ccccggttag
     1441 aaccaaactg actgagcgag ttccaggcac tggcaatact gctgctgaac ccatgcaggg
     1501 cgctttctgc tctgttcgat gcctcccggg ccatttcctg ttgtgccgct gcaatctgac
     1561 gcgttgcatt gataccaacc ggtaaccggg acatcgctcc gcttgcatcc atcaccatat
     1621 taccgtcacg ggtctgtgtg gtggttgcac cactgccggt ctggtacatc atctgaccaa
     1681 acgacgtggt gctgttggtg ctccagctga agccgttcac gttttccgtc tgcatgttgc
     1741 cgtaggagta attaccgtca accacactgc ctgccgcact ggcggtcggg ctgatagcag
     1801 aggaagcgaa atggctgtac acactggaaa atccggcccc gagtcccctg accatcatcc
     1861 aggataatgg cgggatcatc atggaaagat acccggcagt ggaagccaga tcggagtatt
     1921 tcagctgtat ctgtgaaatt tccgagagca ccaccggtgc accattctgc ttcgcataaa
     1981 atgtcatggc gctgttcaga atggcataca acattggcca tgactgcaac cacatcaggg
     2041 caaacacata gcctttcagg acagacagcg tcagtttgtt gaagacagcc gccagtacca
     2101 ggagcgggaa aataccgatg gcgatccccg tcaggatggt ctgcgtcatg ggcagtgtcc
     2161 gcatcgccac atgaccgatg gagacatgtg ccagacgttg cttctccatc gatgacgtgg
     2221 tggccagatt caccaggctg gctgagtcac cattacgtgc tgcataactg gtgatcccct
     2281 ccttcagcgc attaatggtg acattctggc ggatgatctg gctggctgat ttacttgagt
     2341 catagaagta acggtaactg tcgccaatca gcgtactgaa caacaggttc ggatcagggc
     2401 gaccaccaaa taactgctgg gcataataat gccaggtttt tccgccactc tgtgtgtcca
     2461 gattcagctt gtctttcagc gaaaccgacg cgtccttaca ggtcacgaaa ttattattgc
     2521 tgtcataaac gccccgcagc ggactggggc gggaaaaaat cagcgtgtag ggatcattgg
     2581 aggccatcag ctcctccagc gtgtatttgt ggttcaggta aatatccccc atcacacagt
     2641 tctgcacata atcctgaaaa agattggcga tttccggatt gcgggacaaa aagtcggtgc
     2701 tttttgatac cagttctgcg ccaaacagca tccccgtttt gctgtaggtg aaactgtccg
     2761 gttgcgtgta gatcatctcg taactggcca ccattgcatg cccgatacgg gtcgtcagtg
     2821 aaagtggcat cgccagtccg accggcacat tatccacccg atggactttg accaggtcac
     2881 tgttatcaat aatctgcacc gacgtacgga tattaaccag caggctgata agtacaaaca
     2941 ccgccgccca gcccagcaaa tccatcacgt tatggcgctg tacccacata aaggccaccg
     3001 caacaacaga cagggtgaga gcaatttttt caatggaatc ccacgtcctg gttcccataa
     3061 aggcggcaat ggcgttcagg ttattccgca accattcacc accggcaatc acataaactt
     3121 cattcacagc gtgctccctc cgaagtgata gttgttctgg taacgactga gcatgcgggc
     3181 ggaaagctgc tgacgcatgt agctcatctg acgatcgacg accagcagcg catcctgctg
     3241 cacctgtacc tgtgactgaa acgccgcaat ctgccgggtg gcatcattca tattgtcgtt
     3301 aatatgttcg ataactgctt cgtcataatt tcccgtggcc accatcgccc gggcctgctg
     3361 tatcagctcc tgaatgtact gcagcaggat gtcgtaaccg atatagtccg tcagctggta
     3421 aatcatactg ttggaaacac cgagcatctg cgggtcaacc aggtatttga agacggggat
     3481 ggtggtactg gaaataaagc ctttttcctt gtcatccaga ggcgtgtcac tgacagcctt
     3541 gttctgaatg ctggccagaa gtttagtaat ctgagacttc agtgcattat cccggctgat
     3601 ggtcaccggt gtgtctgcca ccactttcag gcatttgtca gaatcgttgc agtgataaat
     3661 ttttgctgta ccgccttcca tcatggcccg gataattgag cggtcagtgg ttctggccga
     3721 tagcggtgtg atttcgccgt tgggaccaaa caccagtgag ccggtcagcg tcatcacaaa
     3781 ctctttcagc tctttgttgc cgtcaaacat tctgtttttg gaaagcgcat tccacatgat
     3841 gttgatgttt ttggtcaccc gctccttatc cttgtcgctg gctttatccc tgacgctgtc
     3901 agatttcccg ccaacggtac atccctgccg ggaagcagcc cagtcagcaa aaatattgct
     3961 ctcaccggca atgtcctgac agactttctg ctgggacacc tgcgtccggg ggaaaagccc
     4021 gccgataatc ccctgtgccg cctggcagga actgaggttc atactgttaa tgtcgcttgc
     4081 cattttctgc aggaagtctt ttgcggtttt gatttccggc accgttgtct gcagggcaag
     4141 gtcaaagaag taaccggcag cattgctcat aatctgctta acaaaacgct gcaactgctc
     4201 gctattaata aagctgaacg agccgagata ggcgtcgatg ccgccacatc cggcattgat
     4261 atccggcagc gtcatggaaa tcagatgaac atttttaacc tgagtacggg catacaggga
     4321 gccaccgtaa gcatagccgg cggcctgccc ctgccagacg cccggctggg tggtattgga
     4381 ggcgaagccc agcttgttaa agaactgatt catgtcgctg ttcacatccg ctgacgctgc
     4441 gggtgtgacc gtcagtaaag cagcacaaag aaccagaaga ggtttaatgc gtggcatcat
     4501 tcttgccctc ccttaatgtg ttctcccggc gcatacggcg tttcagcagg aatatcatga
     4561 tatttccgaa tattaattcg cacattgggg acagaaaaaa tgtaacaaga aaccttgctg
     4621 ccagcgccca taacgtaaac ggaatgactt tcatcagaac attccacata tactggaaat
     4681 taagtaattt cgggtcggcc atccacgaat caatacagac atcgaaaata acgtgcataa
     4741 cagcccataa aacaattccg gcaacaagga aaacaataaa caaataaaaa tatctgtcag
     4801 aacctctgaa actatactca atattccgtc taatttttct gattttgaat tcctgattct
     4861 ttttgttttt tgtcattata agtttcctct gatattactg atgattcatt cagaccggtc
     4921 atgcggctgt aatatatttc agacaccgaa atccatccca caattgcccc cacaaaaaac
     4981 acaacagaaa cagaaaaggt aagacacagc gaaacgacta tttctacagg actggcggga
     5041 taaaaaagcc cctgacggat aaagggaata ttcaggctga cgattattcc cgtcgcgatg
     5101 ccggatattc cggcaatgag taacaccacc tgcttatttc gcaccttttt tccctccgta
     5161 catctgcaga acggtatcca tccgcgccat aaaaccggcg gcatccgttg ccccctgtaa
     5221 aagcggtaat gcctcaagcg tgttgacgtt gaccaggaag gtggtcggtg tggccaccgg
     5281 gatattcggg aagaaggtct gcatcacgtc cggtggcacc ggtaatgctt ccggaaaggc
     5341 catatccccc tgaccatcca gagtgtaggg aaaaacggaa aagccgtact gctgtgccag
     5401 ctgcttcagt accgggtcaa actggtgaca gtaagggcaa tgcccctgca taaacagcac
     5461 caccttccag tcggccaggt taacctgcct gccgttgctg aggcggaacc agcggggagc
     5521 cggcttttct gtcttgtctg tcctggctgg cgtgtctgct gccggttgtg caggctgcgc
     5581 agccataccc tgcggatgcc agagtcgttc aatttcatcc cgggtggagg cctgcacacc
     5641 tgtggccatc atcaacagaa taaccggcag taatttagtg agagacatgt ccgccctcct
     5701 gctgctctgc catcatggcc tgttgcctgg cttccagtgc ctcacgctct tcccggctga
     5761 cacgggcaat ccatgcatcc agcacctggt atgcgccgaa cagcacaagg atggccgcaa
     5821 tcagctccgc cagaaaaaaa gccatccagg gtttgctgtg aacaagacgg gcgacgatat
     5881 gaaaccagac gcccagggaa aatacccaca ttcccgtaat atcaagccgg ggtaaagaga
     5941 atctgcgttt acttatcatg ttaaactccg gttattattt acatgagagt attcatgtct
     6001 gtaatattcg cgtttgtgtg atattagtca gaggtacaaa tggaaaagcg atcttttaaa
     6061 gaaaaactgg aaatagtgag aaacatcata agagagtcat tatcaggtaa tgcggctttt
     6121 gctttactgg tgtattcatt attgcacact ctccccatta aaacctttgc tgatttattt
     6181 gtgacgatac tgttatttat agcaattatc gctgttgtga tatggctatt tctaatcatc
     6241 tatgtttatt tttgtgattt attcagaagt cactggatag cagtctggtt tatcctctgg
     6301 tctgtggtaa tcaacctcac tattggattt ggcatttatg acaaattagc accagtcatt
     6361 tcactaatga aataataaaa aaccacatca ctccagacca tatggctgac aacataatac
     6421 aaataaacat ccttctgaaa ctgtcaaact tcgtgataat cggcatggtg ctgactgcca
     6481 ttgaaacaac cggtacggca cactgattca taaccgcacc acaaagaaac aagaaattat
     6541 ctggcagcat acatacactt atgacattta ctacaaagaa gacaaacgag ctcagtagat
     6601 aaactccttt attatttagt cctgtaaaga aataaccaac aacccccacg ataaacaggc
     6661 tggcacctgt aaaaaaacac aaatcccctg tatgcatata tatcctttgg ttaaaaattc
     6721 ggtttaaaat cctcagagac attcaggaac tgttttgcca ggtcgtcctg cgaaataaaa
     6781 ccgtatgata acggacgaac actaccctgt ttcgggtcaa ccagcatcat ggccgggaaa
     6841 tatttcacgc cgaggcgctg cgcctgcccc tggtcagtcc gggaatccgg caacagcgga
     6901 ttaatcacgc catccacgga aacgggaata acactcagac cataggtatc ccggaagcca
     6961 ttaatgacct gcgccagctg cccgtcgatg gggtcctgcc cccggtaaaa aaacatgatg
     7021 ccgtagtgtt cagccagttt cgcaatggcc tgtcgctgct gcgcctggtc tgctgccagc
     7081 tggttccgta ccgtgccgtt gtaatggctg tactgcaggt tatagtccag ttcaggatgt
     7141 gccagcatgg cctttctggc gctcatggtg aaaagcccgg cctgctgagt ccagtaattt
     7201 tgcagccgga aatatttcac aaaattatcc acgccgggat acagaatggc ttcgtacagc
     7261 gcccgctttg ttgccgtctg cagtgcggcc agtttctgca taatatccgg ttcctgacgg
     7321 ggggctgcag gtacaggttt attttctttt tccttcggat ttattttctc gttataccac
     7381 tgccagcctg catcttttcc tgacgccgga aaaataaagc agcagagtaa cagtggcagt
     7441 aatgctttat tcatcttcat tcctttcatc actttttctt tcatcaggtt tctgcaggtc
     7501 agtcagggca gaaaaacaaa aatacagaat aaacaggagc acaccggagt aaaggataac
     7561 gaaagcagcg gcaagcatcc cgtctgccgt ggtttctttt accgtatccc acgaccagat
     7621 aattaccaga gaaatgacaa tcgctgtaat caaaagccgg ataagaaaat caataaaacg
     7681 gttcgacgtg aatatgactt tcatcatttc ccccggttat ttcccatacc ttactgtcct
     7741 gcctgtttca gctggtcagc aatctgctct ttcactttct gcgtcagaac gccactgtcc
     7801 gggattttct ggttattcat caggtcttcg tagaagttag tgaaatccag tctgttgaac
     7861 tgaattttct gcagctcatc aaccgtaatc ccccgacagt caggatgctt cgcactacca
     7921 aaactgatac gcaactgacc gttgcgcccc tgctgctgga ctatctgcgc cagcttcgaa
     7981 tcaaactgac agtagctgcg ttttttctcc agacagacac ccagcacttt cttcgaacag
     8041 aactccccga cgctgacggt cagtttgttt gattttgctt tagccagggc cttttcatca
     8101 ctgctgcatt tggccagccc gatatcctgt ccccagccgc tgtccttaca gcagttgctg
     8161 tatccggctg cagccttctt acaaaatttc gcctgaccgg tgaaagcacg gacatccacc
     8221 ccgttcagcg ccgcaacatc cttacctgct gcggccagtg ccgccagctg agaaacggct
     8281 tcggcaaaat cattactctg cccgctctga gccttatcgc attcgccatc gagacagaag
     8341 acgtctcccc cacagaccat cactttcccg gatgtttttg actcacagga gtacgtggca
     8401 tattcatgca gacaggcacc ttcttcggag taaaaggcac actggtgtga caccagggta
     8461 caggcaggat tgtcggtgta ggtctgacag gttcccttgt ctgctgactg cgtgacatac
     8521 gtgtcccggt atgcccagca gctctggtac atgctgtatg actgaccgtc tttcaccagc
     8581 gtcctgttcc cgccagcctc cgtacattct gtttttgtca gtttccccag ctccttgctg
     8641 aacgggcagc tttcagacca gacaacatac ggggtgtacg aggctttttt taccctgaca
     8701 accagacgca gcttcattgc cgtatgacgt ttgaattttg tattcccgac ccggacgggg
     8761 tgagatgacg taaaagcaac accggcagtc agtgttttct gtactggtgt aaatgaggca
     8821 tctgctgagt atttggcatt ccagctcagt ggggttccca gtactgtaat tgtcataggt
     8881 acactcttct gcaggtaagt acgactccag ctgtaatgcg catcgacaat ttcaccggta
     8941 acgggagagg taatggagac aacatactga ccattcactt cacgtgcagg tagctgactc
     9001 atttcatact ccagcgtccg ggtttcccat gtggtactcc cctgcagctc catacgggca
     9061 gttcgtgtgc agtactgctc cacctgtaaa tccctctcac aggtgtaatt cgtgtattca
     9121 ctccggctaa tctcctgcgc actgcactgc tgcccggtgt ttcccacaat gctgtcagcc
     9181 cggttcacca catccctgcc ggtctggata aacggtgcat ccggtgaaag aatgtctttc
     9241 ggcttgttca tgaatgactc tgtgatggtt tttccggttt caccggtcgc ccattccgtg
     9301 gtgccgtcat ttttcaggcc gccatccccg ccggcagtca cgccaccgta atattttgtc
     9361 tcgtccggat tcgcgttata gccggggata ctctcctgtg gcttaaagcc ctgaatactg
     9421 ctgcttccct gccctttgat ctggtgagca aaatcaga
//
LOCUS       DAPOAV010000131         8991 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.131, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000131 DAPOAV010000000
VERSION     DAPOAV010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8991
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.131"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            1..712
                     /locus_tag="RN951_004032"
                     /pseudo
     CDS             1..712
                     /locus_tag="RN951_004032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312389.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4049 domain-containing protein"
     gene            974..2596
                     /locus_tag="RN951_004033"
     CDS             974..2596
                     /locus_tag="RN951_004033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4049 domain-containing protein"
                     /protein_id="HDX2528954.1"
                     /translation="MKIGTVAGTNDSTTTIATNDMVQEHVTNFTKELFGYIANGIGDD
                     ISSIARTMLGEVVEKIDDWQIERFQQSIRDDKISFTIQTNHSEKYSMLSDMRAHILRR
                     DNNYQFIVTINSKNYGCYLDNTDINWCSIVYLLNNMTVNDDANDVAVTESYKPVWDWK
                     ISQFNVSDIKFETMINPQFADRTYFSNCSPVDPTSTRPTYFGDTDGSVGAVLYALFAT
                     GHLRIMAEGENFLSQLLNIEDEVLNVLLRENFNEQLDTNVNTIISILNRRDIVLESLQ
                     PYLVINKDAVTPCTFLGDQTGDRFSNICGDQFIIDLLKRIMSINENVHVLAGNHETNC
                     NGNYMQNFTRMKPLDEDTYAGIKDYPVCFYDPKYKIMANHHGITFDEQRKRYIIGPIT
                     VSIDEMTNALDPVELAAIINKKHHAIINGKKFKTSRAISCRSFNRYFSVSTDYRPKLE
                     ALLACSQMLGINQVVAHNGNGGRECIGETGTVLGLNARDSKHAGRMFSMHNCQINPGA
                     GPEITTPWKSYQHEKNRNGLMPLIRRRTMLQL"
     gene            2962..4029
                     /locus_tag="RN951_004034"
     CDS             2962..4029
                     /locus_tag="RN951_004034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HDX2528955.1"
                     /translation="MDKSKRHLAWWVVGLLAVAAIVAWWLLRPAGVPEGFAVSNGRIE
                     ATEVDIASKIAGRIDTILVKEGQFVREGEVLAKMDTRVLQEQRLEAIAQIKEAQSAVA
                     AAQALLEQRQSETRAAQSLVNQRQAELDSVAKRHTRSRSLAQRGAISAQQLDDDRAAA
                     ESARAALESAKAQVSASKAAIEAARTNIIQAQTRVEAAQATERRIAADIDDSELKAPR
                     DGRVQYRVAEPGEVLAAGGRVLNMVDLSDVYMTFFLPTEQAGTLKLGGEARLILDAAP
                     DLRIPATISFVASVAQFTPKTVETSDERLKLMFRVKARIPPELLQQHLEYVKTGLPGV
                     AWVRVNEELPWPDDLVVRLPQ"
     gene            4026..6761
                     /gene="rbbA"
                     /locus_tag="RN951_004035"
     CDS             4026..6761
                     /gene="rbbA"
                     /locus_tag="RN951_004035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated ATPase/putative transporter
                     RbbA"
                     /protein_id="HDX2528956.1"
                     /translation="MTHLELVPVPPVAQLAGVSQHYGKTVALNNITLDIPARCMVGLI
                     GPDGVGKSSLLSLISGARVIEQGNVMVLGGDMRDPKHRRDVCPRIAWMPQGLGKNLYH
                     TLSVYENVDFFARLFGHDKAEREVRINELLTSTGLAPFRDRPAGKLSGGMKQKLGLCC
                     ALIHDPELLILDEPTTGVDPLSRSQFWDLIDSIRQRQSNMSVLVATAYMEEAERFDWL
                     VAMNAGEVLATGSAEELRQQTQSATLEEAFINLLPQAQRQAHQAVVIPPYQPENAEIA
                     IEARDLTMRFGSFVAVDHVNFRIPRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAW
                     LFGQPVDPKDIDTRRRVGYMSQSFSLYNELTVRQNLELHARLFHIPEAEIPARVAEMS
                     ERFKLNDVEDILPESLPLGIRQRLSLAVAVIHRPEMLILDEPTSGVDPVARDMFWQLM
                     VDLSRQDKVTIFISTHFMNEAERCDRISLMHAGKVLASGTPQELVEKRGAASLEEAFI
                     AYLQEAAGQSNEAEAPPVIHDTTHAPRQGFSLRRLFSYSRREALELRRDPVRSTLALM
                     GTVILMLIMGYGISMDVENLRFAVLDRDQTVSSQAWTLNLSGSRYFIEQPPLTSYDEL
                     DRRMRAGDITVAIEIPPNFGRDIARGTPVELGVWIDGAMPSRAETVKGYVQAMHQSWL
                     QDVASRQSTPASQSGLMNIETRYRYNPDVKSLPAIVPAVIPLLLMMIPSMLSALSVVR
                     EKELGSIINLYVTPTTRSEFLLGKQLPYIALGMLNFFLLCGLSVFVFGVPHKGSFLTL
                     TLAALLYIIIATGMGLLISTFMKSQIAAIFGTAIITLIPATQFSGMIDPVASLEGPGR
                     WIGEVYPTSHFLTIARGTFSKALDLTDLWQLFIPLLIAIPLVMGLSILLLKKQEG"
     gene            6761..7885
                     /locus_tag="RN951_004036"
     CDS             6761..7885
                     /locus_tag="RN951_004036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709253.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDX2528957.1"
                     /translation="MRHLRNIFNLGIKELRSLLGDKAMLTLIVFSFTVSVYSSATVTP
                     GSLNLAPIAIADMDQSQLSNRIVNSFYRPWFLPPEMITADEMDAGLDAGRYTFAINIP
                     PNFQRDVLAGRQPDIQVNVDATRMSQAFTGNGYIQNIINGEVNSFVARYRDNSEPLVS
                     LETRMRFNPNLDPAWFGGVMAIINNITMLAIVLTGSALIREREHGTVEHLLVMPITPF
                     EIMMAKIWSMGLVVLVVSGLSLVLMVKGVLGVPIEGSIPLFMLGVALSLFATTSIGIF
                     MGTIARSMPQLGLLVILVLLPLQMLSGGSTPRESMPQMVQDIMLTMPTTHFVSLAQAI
                     LYRGAGFEIVWPQFLTLMAIGGAFFTIALLRFRKTIGTMA"
     gene            complement(8050..>8991)
                     /locus_tag="RN951_004037"
     CDS             complement(8050..>8991)
                     /locus_tag="RN951_004037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1-like element ISEc1 family transposase"
                     /protein_id="HDX2528958.1"
                     /translation="NGIPVHDTIARVVSCISPAKFHECFINWMRDCHSSDDKDVIAID
                     GKTLRHSYDKSRRRGAIHVISAFSTMHSLVIGQIKTDEKSNEITAIPELLNMLDIKGK
                     IITTDAMGCQKDIAEKIQKQGGDYLFAVKGTQGRLNKAFEEKFPLKELNNPEHDSYAI
                     SEKSHGREEIRLHIVCDVPDELIDFTFEWKGLKKLCVAVSFRSIIAEQKKEPEMTVRY
                     YISSADLTAEKFATAIRNHWHVENKLHWRLDVVMNEDDCKIRRGNAAELFSGIRHIAI
                     NILTNDKVFKAGLRRKMRKAAMDRNYLASVLAGSGLS"
BASE COUNT         2291 a         2094 c         2270 g         2336 t
ORIGIN      
        1 ttggggatca tacaggcgat agatttagta ctatttttgg tgataaatat atccttactt
       61 tgctaaattc tatgcgaaat atggagggta ataaagatag ccgtattaat aaaaatgtca
      121 tcgttctggc tagaaatcat gaaatcaatt ttaatggtaa ctatactgca tgactagaaa
      181 attataaact ctctgccggt gatacgtata acttaattaa aacgctcgat gtttgtcatt
      241 atgactcaga aaggaaagtt ttaaccagtc atcacggaat aataagagat gaagaaaaaa
      301 atgttattgt ctcggtgctt tgcaggttcc atttaatcag atgaaaaatc ctactgatcc
      361 tgaggaatta gccaatattt ttaataaaaa acataaagaa cacatggatg atcctctatt
      421 ccatctaatc cgaagcaata ctttgaaacc cacacctgta tatgctaatt attttgataa
      481 cactactgat ttcagaccag cacgtaaacg tatcttcata tatggggaga cactcaaagg
      541 tgaagacccc agcaaataca ttagacaaaa atatgggcat catggggtcg gggtagatca
      601 gaatcaacaa tttgataatg gtattatggg gctaaattcc ctgaaggaag cacgtgataa
      661 aaataataaa ataatttatt cctcagggct tagttgtttt caatctcatt aaaactccat
      721 gaatacggtg gtatgtcttt ttaatcctgc cagtatttca taggttttct taatcgattg
      781 tagaggcatg ttctgatgac gcctctacaa tctttaggga ctttctctgc tatgagataa
      841 gaaatttcat attatgcttt aaggctgaat gatttgtgca aaatataatt atttttccat
      901 cgaacatgag gtgtatgtca taagattaaa tgttaactat gcattcctcg cggtgaatta
      961 tatgaggtaa aagatgaaaa ttggaactgt ggcaggcact aacgacagta caacgacaat
     1021 cgcaacaaat gatatggtgc aagagcatgt tactaacttc actaaagaac tgtttgggta
     1081 tattgcaaat ggtataggtg atgatatatc aagtattgcc aggacaatgc tcggtgaagt
     1141 tgtggaaaaa attgatgatt ggcaaataga acgtttccaa caatctattc gagatgacaa
     1201 aatatcattt accatacaaa cgaatcattc agaaaaatat agtatgctat cggacatgcg
     1261 cgctcatatt ctacgtaggg ataataatta tcagtttatt gtgacaatta atagtaaaaa
     1321 ttacggctgc tatcttgata ataccgatat taattggtgc agcattgttt atttacttaa
     1381 taatatgaca gtaaatgatg atgctaatga tgttgcagtt actgagtcgt acaaacccgt
     1441 ctgggactgg aaaatatcgc aattcaatgt atctgatatt aaattcgaaa caatgataaa
     1501 cccccagttc gctgacagaa cctatttctc caattgttca cctgttgatc ccacaagtac
     1561 cagaccaacc tattttggcg ataccgatgg ctcagtcggt gcagttttgt acgcgctttt
     1621 tgcaacggga catttgagaa tcatggctga aggagaaaat ttccttagcc agttgcttaa
     1681 tatagaagat gaagttctca acgtattgct aagggagaac tttaatgagc aacttgacac
     1741 taatgttaat acaataatca gtattctgaa cagaagagat atagttttag aaagtcttca
     1801 gccttattta gttattaata aagacgctgt gacgccatgt acgtttcttg gcgaccaaac
     1861 cggcgatcga tttagtaata tctgtggcga tcaatttatc atcgatttgt taaaacgcat
     1921 aatgagtatc aatgaaaatg ttcatgtatt agctggaaat catgaaacga attgcaatgg
     1981 taactatatg cagaacttca cgcgtatgaa accacttgat gaggatacct acgctgggat
     2041 aaaagattat cctgtatgtt tctatgaccc caaatacaaa ataatggcaa atcatcatgg
     2101 gataactttt gatgagcagc gaaaacgtta cattatagga ccgataacag tctctattga
     2161 tgaaatgacc aatgctctcg atccggtcga attagcggca attatcaata aaaagcatca
     2221 tgctataatt aatggcaaaa agtttaaaac tagccgggct atctcttgtc gatcctttaa
     2281 tcgttatttt tctgtttcga cagattacag acctaaactt gaagcactat tagcatgttc
     2341 acaaatgtta ggtataaatc aagttgttgc acataacgga aatggtggaa gagaatgtat
     2401 aggtgaaacg gggacagttt taggtcttaa cgcccgtgac agtaaacatg ctggaagaat
     2461 gttcagcatg cataattgcc aaattaaccc tggtgcaggg cctgagataa ccactccctg
     2521 gaagtcttac cagcatgaaa aaaacagaaa tggacttatg cctttgatta gaaggcgcac
     2581 aatgttacag ctctgaacca tagacaacat gaatattaat gttactatct ggttgagact
     2641 gttgataaaa cgtaaaaagg aatgctctgt tcctgcaact gaacaggcgt gaaacgctat
     2701 ccaacaggat ggataccgtt ttgtcagcca gttttataga tcacacttat gagtatgcgt
     2761 gtttcattta cggccaggaa tgctgatgat gacaacatta ctacccgttt tcactaagcc
     2821 ttccccgttg gcgctcaatg ctctgcgcgc tggtcgtatt tgccgtttcc ttcttatccc
     2881 ggatggaaga atccgctgaa cgtcgttcgg cggcagttgt aacacgcgtc gtttgcttac
     2941 agggattatg gcgggtcgat tatggataag agtaagcgcc atctggcgtg gtgggttgtc
     3001 gggttactgg cggtggcggc tatcgtggcg tggtggctgt tgcgcccggc aggtgtgccg
     3061 gaaggctttg ctgtcagtaa tgggcgcatt gaagcgacgg aagtggatat tgccagcaaa
     3121 attgccgggc gtatcgacac cattctggtg aaagaaggcc agtttgttcg cgaaggtgaa
     3181 gtgctggcga agatggatac tcgcgtgttg caggaacagc gactggaagc catcgcgcaa
     3241 atcaaagagg cacaaagcgc cgttgctgcc gcgcaggctt tgctggagca acgacaaagc
     3301 gaaactcgtg ccgcacagtc gctggttaat caacgccagg cagaactgga ctccgtagca
     3361 aaacgtcata cgcgttcccg ttcactggcc caacgagggg ctatttctgc gcaacagctg
     3421 gatgacgatc gcgccgccgc tgagagcgcc cgagctgcgc tggaatcggc gaaagctcag
     3481 gtatcggctt ctaaagcggc tatagaagcg gcacgcacca atatcattca ggcgcaaacc
     3541 cgcgtcgaag cggcacaagc cactgaacgg cgcattgccg cagatatcga tgacagcgaa
     3601 ctgaaagccc cgcgtgacgg acgcgtgcag tatcgggttg ccgagccagg cgaagtgctg
     3661 gcggcaggcg gtcgggtgct gaatatggtc gatctcagcg acgtctatat gactttcttc
     3721 ctgccaaccg aacaggcggg cacgctgaaa ctgggcggtg aagcccggct gatcctcgat
     3781 gccgcgccag atctgcgtat tcctgcaacc atcagttttg tcgccagtgt cgcccagttc
     3841 acgccaaaaa ccgtcgaaac cagcgatgaa cggctgaaac tgatgttccg cgtcaaagcg
     3901 cgtatcccac cggaattact ccagcagcat ctggaatatg tcaaaaccgg tttgccgggc
     3961 gtagcgtggg tgcgggtgaa tgaagaactt ccgtggcctg acgacctcgt ggtgaggttg
     4021 ccgcaatgac gcatctggaa ctggttcccg tcccgcctgt cgcgcaactg gcgggcgtga
     4081 gccagcatta tggaaaaacc gttgcgctga acaatatcac tctcgatatt ccggcccgct
     4141 gtatggtcgg gctgattggc ccggacggcg tcgggaagtc gagcttgttg tcgttgattt
     4201 ccggtgcccg cgtcattgaa cagggcaatg tgatggtgct gggcggcgat atgcgcgacc
     4261 cgaagcatcg ccgcgacgtc tgcccgcgca tcgcctggat gccgcagggg ctgggcaaaa
     4321 acctctacca caccttgtcg gtgtatgaaa acgtcgattt tttcgctcgc ctgttcggtc
     4381 acgacaaagc ggagcgggaa gtgcgaatca atgagctgct gaccagcacc gggttagcac
     4441 cgtttcgcga tcgtccggca gggaaactct ccggcgggat gaagcaaaaa cttgggctgt
     4501 gctgcgcgtt aatccacgac ccggaactgt tgatccttga tgagccaaca acgggggttg
     4561 acccgctctc ccgctcccag ttctgggatc tgatcgacag tattcgccag cggcagagca
     4621 atatgagcgt gctggtcgcc accgcctata tggaagaggc cgaacgcttc gactggctgg
     4681 tagcgatgaa tgccggagaa gtgctggcaa ctggcagcgc cgaagagcta cggcagcaaa
     4741 cgcaaagcgc tacgctggaa gaagcattta taaatctgtt accgcaagcg caacgccagg
     4801 cgcatcaggc ggtagtgatc ccaccgtatc aacctgaaaa cgcagagatt gccatcgaag
     4861 cgcgcgatct gaccatgcgt tttggttcct tcgttgccgt tgatcacgtt aatttccgca
     4921 ttccacgcgg ggagattttt ggttttcttg gttcgaacgg ctgcggtaaa tccaccacca
     4981 tgaaaatgct caccggactg ctgcccgcca gcgaaggtga ggcgtggctg ttcgggcaac
     5041 cggttgatcc aaaagatatc gatacccgcc gtcgggtggg ctatatgtcg cagtcgtttt
     5101 cgctctataa cgaactcacc gtgcggcaaa accttgagtt acatgcccgt ttgtttcaca
     5161 tcccggaagc ggaaattccc gcaagagtgg ctgaaatgag cgagcgtttt aagctcaacg
     5221 acgttgaaga tattctgccg gagtcattgc cgctcggcat tcgccagcgg ctttcgctgg
     5281 cggtggcggt gattcatcgc ccggagatgt taatcctcga tgagcctact tctggtgtcg
     5341 atccggtggc gagggatatg ttctggcagt tgatggtcga tctctcgcgc caggacaaag
     5401 tgactatctt catctccacc cactttatga acgaagcgga acgttgcgac cgcatctcac
     5461 tgatgcacgc cggaaaagtg ctcgccagcg gtacaccgca ggaactggtt gagaaacgcg
     5521 gagccgccag tctggaagag gcatttatcg cctatttgca ggaagcggca ggacagagca
     5581 acgaagccga agcgccgccc gtgatacacg acaccaccca cgcgccgcgt cagggattta
     5641 gcctgcgccg tctgtttagc tacagccgcc gcgaagcact ggaactgcga cgcgatccgg
     5701 tacgttcgac gctggcgctg atgggaacag tgatcctgat gctgataatg ggttacggca
     5761 tcagtatgga tgtggaaaac ctgcgctttg cggtgctcga ccgcgaccag accgtcagta
     5821 gccaggcgtg gacgctcaat ctctccggtt cccgttactt tatcgaacag ccgccgctca
     5881 ccagttatga cgagcttgat cgtcggatgc gtgcgggcga tataacggtg gcaattgaga
     5941 tccctcccaa tttcgggcgc gatatcgcgc gtggtacgcc tgtggaactc ggcgtctgga
     6001 tcgacggagc gatgccgagc cgtgccgaaa cggtaaaagg ttacgtgcag gcaatgcacc
     6061 agagctggct acaggatgtg gcgagccgac aatccacacc cgccagccaa agcgggctga
     6121 tgaatattga gacgcgctat cgctataacc cggacgtaaa aagcctgcca gcgattgttc
     6181 cggcggtgat cccgcttctg ctgatgatga tcccgtcaat gctaagcgcc cttagcgtgg
     6241 tgcgggaaaa agagcttggg tcgattatca acctttacgt gacccccacc acgcgtagtg
     6301 aatttttgct tggtaaacag ttgccataca tcgcgctggg gatgctgaac tttttcctgc
     6361 tctgcggcct gtcggtgttt gtgtttggcg taccgcataa aggcagtttc ctgacgctca
     6421 ccctggcggc gctgctgtat atcatcattg ccaccggaat ggggctgctg atctccacct
     6481 ttatgaaaag ccagattgcc gccattttcg gaacggcgat tatcacgttg atcccggcga
     6541 cacagttttc cgggatgatc gatccggtag cttcgctgga agggcctgga cgttggatcg
     6601 gcgaggttta cccgaccagt cattttctga ctattgcccg cgggacgttc tcgaaagcgc
     6661 tggatctgac tgatttgtgg caacttttta tcccgttgct gatagccatc ccgctggtga
     6721 tgggcttaag tatcctgctg ctgaaaaaac aggagggatg atgcgccatt tacgcaatat
     6781 ttttaatctg ggtatcaaag agttgcgcag tctgctcggt gataaagcga tgctgacgct
     6841 gattgtcttc tcgtttacgg tgtcggtgta ttcgtcagcg accgttacgc caggatcgtt
     6901 gaacctcgcg ccgatcgcca ttgccgatat ggatcaatcg cagttatcga accggatcgt
     6961 taacagcttc tatcgtccgt ggtttttgcc accggagatg atcaccgccg atgagatgga
     7021 tgccggactg gacgccggac gctatacctt cgcgataaat attccgccta attttcagcg
     7081 tgatgtcctc gccggacgcc agccggatat tcaggtgaac gtcgatgcca cgcgcatgag
     7141 ccaggcattt accggcaatg ggtatatcca gaatattatc aacggtgaag tgaacagctt
     7201 tgtcgcgcgc taccgtgata acagcgaacc gttggtatcg ctggaaaccc ggatgcgctt
     7261 taacccgaac ctcgatcccg cgtggtttgg cggggtgatg gcgatcatca acaacattac
     7321 catgctggcg attgtattga ccggatcggc gctgatccgc gagcgtgaac acggcacggt
     7381 ggaacactta ctggtgatgc cgataacgcc gtttgagatc atgatggcga agatctggtc
     7441 gatggggctg gtggtgctgg tggtatcggg attatcgctg gtgctgatgg tgaaaggtgt
     7501 actgggcgta ccgattgaag gctcgatccc gctgtttatg ctgggcgtgg cgctcagtct
     7561 gtttgccacc acgtcaatcg gcatttttat ggggacgata gcgcgttcaa tgccgcaact
     7621 ggggctgctg gtgattctgg tgctgctgcc gctgcaaatg ctttccggtg gttccacgcc
     7681 gcgcgaaagt atgccgcaga tggtgcagga cattatgctg accatgccga cgacacactt
     7741 tgttagcctc gcgcaggcca tcctctaccg gggtgccgga ttcgaaatcg tctggccgca
     7801 gtttctgacg ctgatggcaa ttggcggcgc atttttcacc attgcgctgc tgcgattcag
     7861 gaagacgatt gggacaatgg cgtaaataca attgcccgat gcgtaagctt atagggacta
     7921 cgcatcggtg caatttattg aattttagtt gtttttaggc cggataaggc gtttatgaac
     7981 tgacccccaa aacctggaca gtttcagtta accggctttt tgatactcag tcctgtattc
     8041 agggcaagat tacgaaagcc cgctccccgc aaggactgac gccagatagt ttctgtccat
     8101 ggctgctttt cgcatcttac gtcttaaccc tgccttgaat accttatcat tcgtcaaaat
     8161 attaatagca atgtgccgta tccctgaaaa taattctgct gcatttcctc ttcttatttt
     8221 gcagtcgtct tcattcatta ccacgtccag acgccagtgc agcttattct ccacgtgcca
     8281 gtgatttcgg atcgctgtgg cgaatttctc agcggttaaa tcagcagaac tgatataata
     8341 tctgaccgtc atttctggct ctttcttttg ttctgctatt atggaccgaa aggagactgc
     8401 cacgcataat ttcttcagcc ctttccattc aaacgtgaaa tcaataagtt catcagggac
     8461 atcgcaaaca atatgaagac ggatttcttc tctgccgtga ctcttttcac tgattgcgta
     8521 actgtcatgc tctggattat ttaattcttt cagcggaaat ttttcctcaa aggctttatt
     8581 tagccgcccc tgggttcctt ttaccgcgaa taaataatca cctccctgtt tttgtatctt
     8641 ctctgcaata tctttctggc aacccatcgc atcagttgtg atgatttttc ctttaatatc
     8701 cagcatgtta agaagttctg ggatagctgt aatctcatta gatttctcat ccgtcttgat
     8761 ctgtccgatg accagactgt gcattgttga gaacgcacta atgacatgaa tcgctcccct
     8821 gcggcgactc ttgtcataag agtgccggag cgtttttcca tcaattgcaa tgacgtcttt
     8881 atcatctgaa gaatggcagt cacgcatcca gttaataaag cactcgtgaa attttgcagg
     8941 actgatacag gatacaactc tggcaatggt atcgtgaaca ggaataccat t
//
LOCUS       DAPOAV010000132         8766 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.133, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000132 DAPOAV010000000
VERSION     DAPOAV010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8766
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.133"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..218)
                     /locus_tag="RN951_004038"
     CDS             complement(<1..218)
                     /locus_tag="RN951_004038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528959.1"
                     /translation="MSGKPAARQGDMTQYGGSIVQGSAGVRIGAPTGVACSVCPGGVT
                     SGHPVNPLLGAKVLPGETDIALPGPLPF"
     gene            complement(461..667)
                     /locus_tag="RN951_004039"
     CDS             complement(461..667)
                     /locus_tag="RN951_004039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbfA family protein"
                     /protein_id="HDX2528960.1"
                     /translation="MELYREYPAWLIFLRRTYAVAAGVLALPFMLFWKDRARFYSYLH
                     RVWSKTSDKPVWMDQAEKATGDFY"
     gene            980..1069
                     /gene="kdpF"
                     /locus_tag="RN951_004040"
     CDS             980..1069
                     /gene="kdpF"
                     /locus_tag="RN951_004040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HDX2528961.1"
                     /translation="MSAGVITGVLLVFLLLGYLVYALINAEAF"
     gene            1069..2742
                     /gene="kdpA"
                     /locus_tag="RN951_004041"
     CDS             1069..2742
                     /gene="kdpA"
                     /locus_tag="RN951_004041"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HDX2528962.1"
                     /translation="MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTTGVER
                     VLFRALGVSDREMNWKQYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLA
                     LNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSM
                     STLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFLPYQAVNTVEGAQQLLPMGP
                     VASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVTGD
                     RRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGTDSSINMEGKESRFGVLVSSL
                     FAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVF
                     IAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGP
                     HGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLV
                     SKKSQAASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS"
     gene            2765..4813
                     /gene="kdpB"
                     /locus_tag="RN951_004042"
     CDS             2765..4813
                     /gene="kdpB"
                     /locus_tag="RN951_004042"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HDX2528963.1"
                     /translation="MSRKQLALFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSL
                     LTTCISIAMASGAMPGNALFSAAISGWLWITVLFANFAEALAEGRSKAQANSLKGVKK
                     TAFARKLREPKYGAAADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAITG
                     ESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTPNE
                     IALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGV
                     AGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFIPAQGVDEKTLA
                     DAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRM
                     IRKGSVDAIRRHVEANGGHFPTDVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVK
                     GGIKERFAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQA
                     EGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGK
                     QMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMCLHSPDSAILSAVIFN
                     ALIIVFLIPLALKGVSYKPLTASAMLRRNLWIYGLGGLLVPFIGIKVIDLLLTVCGLV
                     "
     gene            4822..5394
                     /gene="kdpC"
                     /locus_tag="RN951_004043"
     CDS             4822..5394
                     /gene="kdpC"
                     /locus_tag="RN951_004043"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HDX2528964.1"
                     /translation="MSGLRPALSTFIFLLLITGGVYPLLTTVLGQWWFPWQANGSLIR
                     EGDTVRGSALIGQNFTGNGYFHGRPSATAEMPYNPQASGGSNLAVSNPELDKLIAARV
                     AALRAANPDASASVPVELVTASASGLDNNITPQAAAWQIPRVAKARNLSVEQLTQLIA
                     KYSQQPLVKYIGQPVVNIVELNLALDKLDE"
     gene            5387..8071
                     /gene="kdpD"
                     /locus_tag="RN951_004044"
     CDS             5387..8071
                     /gene="kdpD"
                     /locus_tag="RN951_004044"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     KdpD"
                     /protein_id="HDX2528965.1"
                     /translation="MNNEPLRPDPDRLLEQTAAPHRGKLKVFFGACAGVGKTWAMLAE
                     AQRLRAQGLDIVVGVVETHGRKDTAAMLEGLAVLPLKRQAYRGRHISEFDLDAALARR
                     PALILMDELAHSNAPGSRHPKRWQDIEELLEAGIDVFTTVNVQHLESLNDVVSGVTGI
                     QVRETVPDPFFDAADDVVLVDLPPDDLRQRLKEGKVYIAGQAERAIEHFFRKGNLIAL
                     RELALRRTADRVDEQMRAWRGHPGEEKVWHTRDAILLCIGHNTGSEKLVRAAARLASR
                     LGSVWHAVYVETPALHRLPEKKRRAILSALRLAQELGAETATLSDPAEEKAVVRYARE
                     HNLGKIILGRPASRRWWRRETFADRLARIAPDLDQVLVALDEPPARTINNAPDNRSFK
                     DKWRVQIQGCVVAAALCAVITLIAMQWLMAFDAANLVMLYLLGVVVVALFYGRWPSVV
                     ATVINVVSFDLFFIAPRGTLAVSDVQYLLTFAVMLTVGLVIGNLTAGVRYQARVARYR
                     EQRTRHLYEMSKALAVGRSPQDIAATSEQFIASTFHARSQVLLPDDNGKLQPLTHPQG
                     MTPWDDAIAQWSFDKGLPAGAGTDTLPGVPYQILPLKSGEKTYGLVVVEPGNLRQLMI
                     PEQQRLLETFTLLVANALERLTLTASEEQARMASEREQIRNALLAALSHDLRTPLTVL
                     FGQAEILTLDLASEGSPHARQASEIRQHVLNTTRLVNNLLDMARIQSGGFNLKKEWLT
                     LEEVVGSALQMLEPGLSSPINLSLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQAE
                     IGIDAHVEGENLQLDVWDNGPGLPPGQEQTIFDKFARGNKESAVPGVGLGLAICRAIV
                     DVHGGTITAFNRPEGGACFRVTLPQQTAPELEEFHEDM"
     gene            8068..8745
                     /gene="kdpE"
                     /locus_tag="RN951_004045"
     CDS             8068..8745
                     /gene="kdpE"
                     /locus_tag="RN951_004045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator KdpE"
                     /protein_id="HDX2528966.1"
                     /translation="MTNVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATR
                     KPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSARSEESDKIAALDAGADDYLSKP
                     FGIGELQARLRVALRRHSATTAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLL
                     AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETG
                     IGYRFML"
BASE COUNT         1846 a         2288 c         2539 g         2093 t
ORIGIN      
        1 atgaacggca gcgggccggg cagggcgatg tcggtttcac cgggaaggac ctttgcaccg
       61 agcagcggat tgaccggatg gccggacgtc accccgccgg ggcacaccga acaggccacg
      121 ccggtggggg caccgatgcg taccccggct gaaccctgga caatgctacc gccatactgc
      181 gtcatgtcgc cctgacgcgc cgccggtttt ccgctcatct gctcatcctt gttttatcgg
      241 gttatttgtc tgctgacagg cgaaacccta cagatttata agaaagcctt aagtgagata
      301 tctgtcagat aagaacaatt aggaaaatat ttatatatat ttcatgaata tatgtttcga
      361 ttggtataac gatgtctaaa tattcctctg aacatcttcc tgatacaaaa aaccgccagc
      421 gtttccgctg gcggttttca atgtattcaa aactcagcaa tcaataaaaa tcaccagttg
      481 ccttttcggc ctgatccatc cacaccggtt tatcgctggt tttcgaccag acgcgatgca
      541 ggtagctgta aaagcgggcg cggtctttcc agaaaagcat gaaaggcagc gccagaacgc
      601 ccgctgcaac cgcataagta cggcgtaaaa agataagcca tgcaggatat tctctgtaga
      661 gttccatact tttctccccc ttttgtatct acccggtgaa tggcaccgga aaaatgaatt
      721 tgtttatctg atgaaaatag taccgccttt tgtgtaattt tactactcat ccgaccactt
      781 atttttgctt attgatggtt tatttacatt catcctgtaa ttaagttaca caaaagttaa
      841 attaatacta aacattagtt aaatcatggc ttttgccatt tttatacttt ttttacaccc
      901 cgcccgcaga tttttgcgaa atctttgcag ccagaattct acccttccgg tatcactttt
      961 aggccactgg aggtgcactg tgagtgcagg cgtgataacc ggcgtattgc tggtgttttt
     1021 attactgggt tatctggttt atgccctgat caatgcggag gcgttctgat ggctgcgcaa
     1081 gggttcttac tgatcgccac gtttttactg gtgttaatgg tgctggcgcg tcctttaggc
     1141 agcgggctgg cgcggctgat taatgacatt cctcttcccg gtacaacggg cgttgagcgc
     1201 gtactttttc gcgcacttgg cgtctctgac cgtgagatga actggaagca atatctttgt
     1261 gccattctcg gcctgaacat gctggggctg gcggtgctgt tttttatgtt gctcggtcag
     1321 cactatctgc cgcttaatcc acagcagttg ccagggctgt cgtgggatct ggcgctgaat
     1381 accgccgtca gctttgtcac caataccaac tggcaatctt atagcggtga aaccacgttg
     1441 agctatttca gccagatggc gggcttaacg gtgcaaaact ttctttctgc cgccagcggg
     1501 attgcggtga tttttgccct catccgtgcg tttacccgcc agagcatgag cacgctcggg
     1561 aatgcctggg tcgatctgct acgcatcacg ttatgggtgc tagtccctgt ggcgttgttg
     1621 attgcactgt tttttattca acaaggtgcg ctgcaaaact ttctgcctta tcaggctgtg
     1681 aataccgttg aaggagcgca acagctgtta cccatggggc ctgtagcttc tcaggaagcg
     1741 atcaagatgc tcggtactaa cggcggtggc ttctttaatg ccaactcgtc gcatccgttt
     1801 gaaaacccaa ccgcactgac caacttcgtg cagatgctgg cgatcttctt gatcccaacg
     1861 gcgctgtgct ttgcctttgg tgaagtgacg ggcgatcgcc gccaggggcg catgttgctg
     1921 tgggcgatgt cagtgatttt tgtcatctgc gtaggcgtgg tgatgtgggc agaagttcag
     1981 ggtaatcctc atctgctggc actgggcacg gacagcagca tcaatatgga aggtaaagag
     2041 agccgtttcg gcgtgctggt cagtagcctg tttgcggtcg tgacgacggc ggcttcctgt
     2101 ggcgcggtga ttgcgatgca tgattcgttt accgctctcg gtggcatggt gccgatgtgg
     2161 ctgatgcaaa ttggtgaagt ggtgttcggc ggtgtcggtt ctggtcttta cggcatgatg
     2221 ctgtttgtcc tgctggcggt gtttattgcc gggctgatga ttggtcgtac accggaatat
     2281 ctgggtaaaa aaatcgacgt acgcgagatg aaactgactg cactggcaat tctggttacc
     2341 ccgacgctgg tgctgatggg cgcggcgttg gcgatgatga ccgacgccgg acgtagcgcc
     2401 atgctcaacc ctggcccgca tggttttagc gaagtgctgt acgccgtgtc atccgccgct
     2461 aacaacaacg gcagcgcctt tgccggatta agcgccaact ctccgttctg gaactgttta
     2521 ctggcgttct gcatgtttgt cggtcgcttc ggggtgatta tcccggtgat ggcaattgcc
     2581 ggttcgctgg tgagtaaaaa gagccaagcc gccagctccg gcacgctgcc aacgcacggc
     2641 ccgctgtttg ttggcctgtt aatcggcacc gtgttgctgg ttggcgcact gacctttatc
     2701 cctgccctgg cgcttggtcc ggtggcggaa tatctctcct gatgatattg agtgagcact
     2761 gaatatgagt cgtaaacaac tggcgctatt cgaaccaaca cttgtcgttc aggcgctgaa
     2821 agaagcggtg aaaaaattaa acccgcaggc gcaatggcgc aatccggtga tgtttatcgt
     2881 ctggatcggc agtctgctga ccacctgtat tagcatcgcg atggcaagcg gtgcgatgcc
     2941 cggcaatgcg ctgtttagcg cggccattag cggttggctg tggatcaccg tactgttcgc
     3001 taatttcgcc gaggcgctgg cagaaggccg cagtaaagcg caggccaaca gtctgaaagg
     3061 ggtgaaaaaa actgcctttg cccgcaagct gcgtgagccg aaatatggcg ctgcggcgga
     3121 caaagttcct gccgaccaac ttcgtaaagg cgatatcgta ctggtagaag ctggcgatat
     3181 tatcccctgc gatggtgaag ttattgaagg gggtgcatcg gtcgatgaaa gcgccatcac
     3241 cggggaatcg gcaccggtga tccgtgaatc cggcggcgat tttgcctccg tcaccggcgg
     3301 cacgcgtatt ctttctgact ggctggtgat tgagtgtagc gttaaccccg gcgagacatt
     3361 tctggatcgg atgatcgcga tggtggaagg cgcacagcga cgcaaaacgc cgaacgaaat
     3421 tgccctgacc attctgctga ttgccctgac tatcgtcttt ttactggcaa ccgccacgct
     3481 gtggccgttt tccgcgtggg gcggtaatgc agtcagcgta acggtactgg tggcgctgct
     3541 ggtctgtctg atcccaacca ctattggcgg cctgttgtca gcgatcggcg tcgccgggat
     3601 gagccggatg ctaggcgcga atgtgattgc caccagcgga cgtgcagttg aagcggcagg
     3661 tgacgttgac gttctgctac tggataaaac cggcaccatc acactcggta accgtcaggc
     3721 gtcggagttt atccccgcgc agggcgtgga tgaaaaaacg ctggctgacg ccgcacaact
     3781 ggcttcgctg gctgatgaaa cgccggaagg ccgcagtatt gtgatcctcg ccaagcagcg
     3841 ttttaacctg cgcgagcgcg atgtgcagtc gctccatgcc acctttgtac cgtttactgc
     3901 gcaaagccgg atgagcggga tcaacatcga caaccgcatg atccgtaaag gttctgtcga
     3961 tgccattcgt cgccatgttg aggctaacgg tggtcacttc cctaccgatg ttgatcaaaa
     4021 agtcgatcag gttgcgcgtc agggagccac gccgctggtg gtggtggaag gttctcgtgt
     4081 gctgggcgtt attgcgctga aagatatcgt caaaggcggt attaaagagc gcttcgccca
     4141 gctgcgcaaa atgggcatta aaacggtgat gattaccggc gataaccgtc tgactgccgc
     4201 cgcgattgct gcggaagcgg gtgtcgatga ttttctcgcc gaagcgacac cggaggccaa
     4261 gctggcattg atccgtcagt atcaggcgga aggtcgtttg gtagcgatga ccggcgacgg
     4321 caccaacgat gctccggcgc tggcgcaggc agatgtcgcg gtggcgatga actccggcac
     4381 ccaggcggcg aaagaggcgg gcaatatggt cgatctcgac tctaacccga ccaagttgat
     4441 cgaggtggtg cacattggca aacagatgct gatgacccgt ggctcgctga ccaccttcag
     4501 cattgccaac gatgtggcga aatacttcgc cattattccg gcggcattcg cggcaacgta
     4561 tccgcagtta aatgcgctga acatcatgtg cctgcattcg cccgactccg caatcctcag
     4621 tgcggtgatt ttcaacgcct tgattatcgt ctttttgatt cccctggcgt taaaaggcgt
     4681 gagttataaa ccgcttaccg cttctgccat gttgcgccgt aacttatgga tttacggtct
     4741 gggtgggctg ctggtgccgt ttatcggtat caaagtcatt gatttactgc tgaccgtttg
     4801 cggtctggtg tgaggtttac catgagtgga ttacgtccgg cattatcaac atttatcttt
     4861 ctgttattga ttactggcgg cgtttacccg ctgctgacca ccgtactggg gcaatggtgg
     4921 tttccctggc aggccaatgg ttcgttgatt cgtgaaggtg atacggtgcg cggttcggca
     4981 ttaatcgggc agaattttac cggcaacggc tattttcatg gtcgcccgtc ggcaacggca
     5041 gaaatgccct ataatccaca ggcttctggc gggagcaatc tggcggtcag taaccctgag
     5101 ctggataaac taatagccgc acgcgttgct gcattacggg ccgctaaccc ggatgccagc
     5161 gcgagcgttc cggttgaact ggtgacggca tcggcaagcg ggctggacaa taatatcacc
     5221 ccgcaagcgg cggcctggca aatcccacgc gtggcgaaag cgcgtaatct cagcgttgaa
     5281 cagctcacgc aactgatcgc aaaatacagc caacaaccgc tggtgaaata tatcggccag
     5341 ccggttgtca acattgttga actcaatctg gcgctggata aacttgatga ataacgaacc
     5401 cttacgtccc gaccccgatc gtctgctgga acaaactgcc gcgccgcatc gggggaagct
     5461 gaaagttttc ttcggtgcct gtgcaggcgt cgggaagacc tgggcgatgc tggcagaagc
     5521 ccagcgactg cgggcgcaag ggctggatat tgtggttggc gtggtagaaa cccacgggcg
     5581 aaaagatacc gccgccatgc tggaagggct ggctgttctg ccgttaaaac gccaggcgta
     5641 ccgtgggcgg catatcagcg agtttgatct cgatgccgcc ctcgcccgcc gcccggcgct
     5701 gatcttaatg gacgaactgg cgcacagtaa tgcgccaggt tcccgtcatc ccaaacgctg
     5761 gcaggatatc gaagaactgc tggaagctgg cattgatgtt ttcactaccg tcaacgttca
     5821 gcatctggaa agtctgaatg atgtggtcag cggcgtcacc ggaattcagg tacgggaaac
     5881 cgtgcccgat ccttttttcg atgccgccga cgacgtggtg ctggtggact tgcccccgga
     5941 cgatctgcgc cagcggctga aagaaggcaa agtctatatt gccgggcagg cggagcgcgc
     6001 cattgaacat tttttccgca aaggtaatct gatcgccctg cgcgaactgg cactgcgccg
     6061 tactgccgat cgcgttgatg agcaaatgcg cgcctggcgg gggcatcctg gcgaagagaa
     6121 agtgtggcac acgcgcgacg cgatcctttt atgcatcggc cataacaccg gcagcgaaaa
     6181 actggtccgc gcagcggcgc ggctggcgtc acggctgggt agcgtctggc acgcggtgta
     6241 tgttgaaacc cctgccctgc accgcttacc ggaaaaaaaa cgtcgggcaa ttctcagcgc
     6301 cttacgtctg gcgcaggaac tgggcgcgga gacggcaaca ctttctgatc cagcggaaga
     6361 gaaagcggta gtgcgttatg cccgtgaaca taatctcggc aagattattc tcggtcgccc
     6421 ggcctcgcgc cgctggtggc gtcgggaaac gtttgctgac cgactggcgc gcatcgcccc
     6481 cgatctcgat caggtgctgg tcgcgcttga tgaaccaccc gcccgcacga ttaacaacgc
     6541 gccggataac cgctctttta aagacaagtg gcgtgtacaa attcagggat gcgtggttgc
     6601 cgccgcgtta tgcgccgtta tcaccttaat tgccatgcag tggctgatgg cgtttgatgc
     6661 cgccaacctg gtgatgctgt atctgcttgg cgtggtggtg gtggcgctat tttatggacg
     6721 ctggccttca gtggttgcca ccgtcattaa tgtagtgagt ttcgatctct tttttatcgc
     6781 cccacgcggc acgctcgccg tctctgatgt gcaatatctg ctgaccttcg cggtgatgtt
     6841 aaccgtcggg ctggtgatcg ggaaccttac tgctggcgtg cgttatcagg cgcgggtagc
     6901 ccgttaccgc gagcaacgca cacggcactt atatgaaatg tcgaaagctc tggcggtggg
     6961 ccgcagtccg caggatatcg ctgccaccag cgaacaattt attgcctcca cgtttcatgc
     7021 ccgcagtcag gtgttgttgc ccgatgacaa cggtaaattg cagccgttaa cacatccgca
     7081 aggaatgacg ccgtgggacg atgccatcgc gcagtggagt tttgataaag gcctgcctgc
     7141 gggcgcgggc accgacacgt tacccggtgt accgtaccag attttgccgc taaaaagcgg
     7201 cgagaaaacc tacgggctgg tggtggtgga gccggggaat ctgcgccagt tgatgatccc
     7261 ggaacagcag cgcctgctgg agacgtttac gctgttagtc gccaatgccc ttgagcggct
     7321 gacgctaacc gccagcgaag aacaggcgcg gatggcaagc gaacgtgaac agatccgcaa
     7381 cgccctgctg gcggcgcttt cgcatgattt acgcacgccg cttacggtgc tgtttggtca
     7441 ggcagaaatc ttaacgctcg atctggcaag cgaaggatca ccccacgccc gccaggccag
     7501 cgagatccgt cagcatgtgc tgaacactac ccgactggtg aataatctac tggatatggc
     7561 gcgaattcag tccggcggct ttaatttgaa gaaagagtgg ttaacgctgg aagaagtagt
     7621 cggcagcgcg ctgcaaatgc tggaaccggg tttatcgtcg cccatcaatc tttctctgcc
     7681 agaaccgctg accttaatcc acgttgacgg gccactcttt gaacgggtgc tgattaatct
     7741 gctggagaac gcggtgaaat atgcgggtgc gcaggccgaa attggtatcg atgcccacgt
     7801 tgagggcgaa aatctacaac tggatgtctg ggataacggc cccggtcttc cgccaggcca
     7861 ggagcagacg atatttgata agtttgctcg cgggaataaa gagtcggcag taccgggggt
     7921 agggcttgga ctggcaattt gtcgggcgat agtggatgta cacgggggca ctattaccgc
     7981 gttcaaccga ccggaaggtg gtgcctgttt tcgtgttaca cttccccagc aaactgcccc
     8041 tgaacttgaa gaatttcatg aggatatgtg acaaacgttc tgattgttga agatgaacag
     8101 gctattcgtc gctttctgcg cacggcgctg gagggcgacg ggatgcgcgt ctttgaggcc
     8161 gaaacgctgc aacgcggctt gctggaagcg gcaacccgta agccagattt gattattctc
     8221 gatctcggcc tgcccgatgg tgatgggatt gagtttatcc gcgacctgcg ccagtggagc
     8281 gcggtgccgg tgattgtgct ttccgcacgc agcgaagaga gcgacaaaat cgccgcgctg
     8341 gatgccggag cggatgatta tctgagtaag ccgtttggca ttggcgaatt gcaggcccgt
     8401 ctgcgcgtcg cattacgccg ccactctgcc accaccgcgc ccgatccgct ggtaaaattt
     8461 tccgatgtta ccgtcgattt agccgcccgc gtgattcacc ggggtgagga agaggtgcat
     8521 ctcacaccaa ttgagttccg cctgctggcg gtgctgctca acaatgccgg aaaagtactc
     8581 acccagcgcc agctccttaa ccaggtgtgg gggccaaacg cggtcgaaca cagtcactat
     8641 ttgcgtattt atatgggaca tctgcgacaa aaactggaac aggatcccgc ccgcccacgc
     8701 catttcatta ctgaaaccgg tattggctat cggtttatgc tttgaatatt aattttaata
     8761 cagcct
//
LOCUS       DAPOAV010000133         8765 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.134, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000133 DAPOAV010000000
VERSION     DAPOAV010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8765
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.134"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..550)
                     /locus_tag="RN951_004046"
     CDS             complement(<1..550)
                     /locus_tag="RN951_004046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2528967.1"
                     /translation="MSSKIEDTPQKTLSCWPLAFSAGLLGIGQNGLLVVLPVLVIQTN
                     LSLSVWAALLMLGSMLFLPSSPWWGKQISLTGSKTVVLWALGGYGVSFTLLGLGSVLM
                     ATGAVTTAVGLGILIIARIVYGLTVSAMVPACQVWALQRAGEGNRMAALATISSGLSC
                     GRLFGPLCAAAMLVIHPLAPVWM"
     gene            686..2410
                     /gene="iucA"
                     /locus_tag="RN951_004047"
     CDS             686..2410
                     /gene="iucA"
                     /locus_tag="RN951_004047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001314127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerobactin synthase IucA"
                     /protein_id="HDX2528968.1"
                     /translation="MILPSEKSATDVAAQCFLNALIRETKDWQLAEYPPDELIIPLDE
                     QKSLHFRVAYFSPTQHHRFAFPAHLVTASGSYPVDFTTLSRLIIDKLRHQLFLPVPLC
                     ETFHQRVLESYAHTQQTIDARHDWAILREKALNFGEAEQALLTGHAFHPAPKSHEPFN
                     RQEAERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDN
                     QWLFPLHPWQGEYLLQQVWCQALFAKGLIRDLGEAGTSWLPTTSSRSLYCATSRDMIK
                     FSLSVRLTNSVRTLSVKEVERGMRLARLAQTDGWQMLQARFPTFRVMQEDGWAGLRDL
                     NGNIMQESLFSLRENLLLEQPQSQTNVLVSLTQAAPDGGDSLLVSAVKRLSDRLGITV
                     QQAAHAWVDAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSA
                     FMPHATEWLDTIDEAQAENIFTREQLLRYFPYYLLVNSTFAVTAALGAAGLDSEANLM
                     ARVRTLLAEVRDQVTHKTCLNYVLESPYWNVKGNFFCYLNDHNENTIVDPSVIYFDFA
                     NPLQAQEV"
     gene            2411..3358
                     /gene="iucB"
                     /locus_tag="RN951_004048"
     CDS             2411..3358
                     /gene="iucB"
                     /locus_tag="RN951_004048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(6)-hydroxylysine O-acetyltransferase"
                     /protein_id="HDX2528969.1"
                     /translation="MSGANIVHSGYGLRCEKLDKPLNLGWGLDNSAVLHWPGELPTGW
                     LCDALDQIFIAAPQLSAVVLPWSEWCEEPQALTLFGQVQSDIIHRSAFWQLPLWLSSP
                     ANRASGEMVFDAEREIYFPQRPPRPQGEVYRRYDPRIRRMLSFRIADPVSDAERFTRW
                     MNDPRVEYFWEQSGSLEVQIAYLERQLTSKHAFPLIGCFDDRPFSYFEIYWAAEDRIG
                     RHYSWQPFDRGLHLLVGEQQWRGAHYVQSWLRGVTHYLLLNEPRTQRTVLEPRTDNQR
                     LFRHLEPAGYRTIKEFDFPHKRSRMVMADRHHFFTEVGL"
     gene            3358..5100
                     /gene="iucC"
                     /locus_tag="RN951_004049"
     CDS             3358..5100
                     /gene="iucC"
                     /locus_tag="RN951_004049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerobactin synthase IucC"
                     /protein_id="HDX2528970.1"
                     /translation="MNHKDWDLVNRRLVAKMLSELEYEQVFHAESQGDDRYCINLPGA
                     QWRFIAERGIWGWLWIDAQTLRCADEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYAT
                     LLGDLQLLKARRGLSASDLINLNADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEY
                     ANTFRLHWLAVKREHMIWRCDNEMDIHQLLTAAMDPQEFARFSQVWQENGLDHNWLPL
                     PVHPWQWQQKIATDFIADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPL
                     TIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYA
                     ALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLD
                     AETWLTQLFRVVVVPLYHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLV
                     KEEFPEMDSLPQEVRDVTSRLSADYLIHDLQTGHFVTVLRFISPLMVRLGVPERRFYQ
                     LLAAVLSDYMKKHPQMSERFALFSLFRPQIIRVVLNPVKLTWPDLDGGSRMLPNYLED
                     LQNPLWLVTQEYES"
     gene            5097..6374
                     /gene="iucD"
                     /locus_tag="RN951_004050"
     CDS             5097..6374
                     /gene="iucD"
                     /locus_tag="RN951_004050"
                     /EC_number="1.14.13.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001354579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent L-lysine N(6)-monooxygenase"
                     /protein_id="HDX2528971.1"
                     /translation="MKKSVDFIGVGTGPFNLSIAALSHQIEELDCLFFDEHPHFSWHP
                     GMLVPDCHMQTVFLKDLVSAVAPTNPYSFVNYLVKHKKFYRFLTSRLRTVSREEFSDY
                     LRWAAEDMNNLYFSHTVENIDFDKKRRLFLVQTSQGEYFARNICLGTGKQPYLPPCVK
                     HMTQSCFHASEMNLRRPDLSGKRITVVGGGQSGADLFLNALRGEWGEAAEINWVSRRN
                     NFNALDEAAFADEYFTPEYISGFSGLEEDIRHQLLDEQKMTSDGITADSLLTIYRELY
                     HRFEVLRKPRNIRLLPSRSVTTLESSGPGWKLLMEHHLDQGRESLESDVVIFATGYRS
                     ALPQILPSLMPLITMHDKNTFKVRDDFTLEWSGPKENNIFVVNASMQTHGIAEPQLSL
                     MAWRSARILNRVMGRDLFDLSMPPALIQWRSGT"
     gene            6456..8657
                     /gene="iutA"
                     /locus_tag="RN951_004051"
     CDS             6456..8657
                     /gene="iutA"
                     /locus_tag="RN951_004051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004213924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric aerobactin receptor IutA"
                     /protein_id="HDX2528972.1"
                     /translation="MMISKKYTLWALNPLLLTMMAPAVAQQTDDETFVVSANRSNRTV
                     AEMAQTTWVIENAELEQQIQGGKELKDALAQLIPGLDVSSRSRTNYGMNVRGRPLVVL
                     VDGVRLNSSRTDSRQLDSIDPFNIDHIEVISGATSLYGGGSTGGLINIVTKKGQPETM
                     MEFEAGTKSGFSSSKDHDERIAGAVSGGNEHISGRLSVAYQKFGGWFDGNGDATLLDN
                     TQTGLQYSDRLDIMGTGTLNIDESRQLQLITQYYKSQGDDDYGLNLGKGFSAIRGTST
                     PFVSNGLNSDRIPGTERHLISLQYSDSAFLGQELVGQVYYRDESLRFYPFPTVNANKQ
                     VTAFSSSQQDTDQYGMKLTLNSKPMDGWQITWGLDADHERFTSNQMFFDLAQASASGG
                     LNNKKIYTTGRYPSYDITNLAAFLQSGYDINNLFTLNGGVRYQYTENKIDDFIGYAQQ
                     RQIAAGKATSADAIPGGSVDYDNFLFNAGLLMHITERQQAWLNFSQGVELPDPGKYYG
                     RGIYGAAVNGHLPLTKSVNVSDSKLEGVKVDSYELGWRFTGNNLRTQIAAYYSISDKS
                     VVANKDLTISVVDDKRRIYGVEGAVDYLIPDTDWSTGVNFNVLKTESKVNGTWQKYDV
                     KTASPSKATAYIGWAPDPWSLRVQSTTSFDVSDAQGYKVDGYTTVDLLGSYQLPVGTL
                     SFSIENLFDRDYTTVWGQRAPLYYSPGYGPASLYDYKGRGRTFGLNYSVLF"
BASE COUNT         2048 a         2323 c         2328 g         2066 t
ORIGIN      
        1 gcatccacac tggcgccaga gggtgaatga ccaacattgc cgccgcgcac agcggcccga
       61 atagcctgcc gcagctcagg ccggagctga tggttgccag agcggccatg cgattccctt
      121 ctcccgctct ctgcaatgcc cagacctgac aggctggcac cattgctgac acggtcagac
      181 cgtagacgat ccgggcgatg attaatattc ccaaccccac cgctgttgtt acggcaccgg
      241 tagccatcag cacgcttccc agcccaagca gggtaaagct tacgccatat cctcccagag
      301 cccacagcac cacagtctta ctgccagtaa gggaaatttg ctttccccac catggggaag
      361 atggcagaaa cagcattgag cccagcatca gcagggcagc ccatacagac agactcagat
      421 ttgtctgtat gaccagaaca gggagtacaa ccagcagacc gttctgtccg ataccgagaa
      481 gaccggcact gaacgccagt ggccagcagg acagggtttt ttggggcgta tcttcgatct
      541 tagatgacat tgtaatgttt caacaccatg tattaattgt gtttatttgt aaaattaatt
      601 tttctgacaa taacatttct cgttgataat gagaatcatt attgacataa ttgttattat
      661 tttactgtgt aggagctgtt tgattatgat cctgccctct gaaaaatccg ccacagatgt
      721 ggctgcgcag tgcttcctga atgccttgat tcgtgaaacc aaagactggc aactggcgga
      781 atacccgcca gacgaattga ttatcccgct ggacgaacag aagtcgctcc atttcagagt
      841 ggcttatttc tccccaaccc agcatcaccg ctttgcattt cctgctcatc tggtcacggc
      901 atcaggcagt tatcctgtcg actttaccac tctctcccgg cttattattg ataagctccg
      961 gcatcaactt tttctgccag ttcccctctg cgaaactttc caccaacgcg tgctggaaag
     1021 ctacgcccat acgcaacaga caattgatgc ccgccatgac tgggccatcc tgcgtgaaaa
     1081 agcgttgaat tttggcgagg ctgagcaggc actgctgaca ggacacgctt tccaccctgc
     1141 acctaagtct catgaaccgt ttaaccgcca ggaagctgaa cgatacctgc ctgacatggc
     1201 acctcacttc ccgctgcggt ggttttcggt ggataaaacg caaatcgctg gtgaaagtct
     1261 gcatcttaac cttcaacagc ggttgacgcg atttgccgca gaaaatgcgc cccagttact
     1321 caacgaatta agtgacaatc aatggctgtt cccgctgcac ccgtggcagg gagaatatct
     1381 tttgcagcaa gtgtggtgcc aggcactttt tgctaaagga cttatcagag acttaggcga
     1441 ggccggcacg tcgtggctgc cgaccacctc ttcccgctcc ctctactgtg ctaccagccg
     1501 cgatatgatc aagttctccc tgagcgttcg gctgaccaac tccgtccgta ctctgtctgt
     1561 gaaagaggtg gagcgaggaa tgcgcctggc acgtctggcg caaaccgacg gctggcagat
     1621 gctacaggcc cgcttcccta ctttccgggt aatgcaggag gacggctggg ccgggctgcg
     1681 cgatcttaac ggcaacatca tgcaggaaag tttgttttcc ctgcgtgaaa acctgctgct
     1741 ggagcagccg caaagccaga ccaacgttct ggtttccctg actcaggccg caccggatgg
     1801 cggtgattcg ctgctggttt cggcggtaaa acgcctgagc gatcgcctcg gtatcactgt
     1861 gcaacaggcc gcccacgcat gggtcgatgc ttactgtcag caggtgctga agcctctgtt
     1921 tacggctgaa gcggattacg gcctggtgct gctggcgcat cagcaaaata ttcttgtgca
     1981 gatgcttggg gatctgccgg tcggatttat ttaccgtgac tgccagggca gcgcgtttat
     2041 gcctcacgcg acagagtggc tcgataccat tgacgaggcg caggcggaaa atattttcac
     2101 ccgtgagcag ttgctgcgct atttccctta ttacctgctg gttaactcca cttttgccgt
     2161 aactgctgcg ctgggtgctg ccgggctgga cagcgaagcg aatctgatgg ctcgtgtacg
     2221 aacattgctg gctgaagtgc gtgaccaggt gactcataaa acctgtctca actatgttct
     2281 ggaaagtccg tactggaacg taaaaggtaa ctttttctgt tatctgaacg atcataacga
     2341 gaacaccatc gttgaccctt cggtgatcta ttttgatttc gctaacccgc tgcaggctca
     2401 ggaggtctga atgtctgggg caaacattgt tcacagcgga tatggactgc gctgtgaaaa
     2461 actcgacaag cctctgaatc ttggctgggg gctggacaat agcgcggtgt tgcactggcc
     2521 cggggagctg ccaacagggt ggctgtgcga cgcgctggat cagatattta tcgccgcacc
     2581 acaactttca gcagtggttc ttccctggtc cgaatggtgt gaggagccac aggcgctgac
     2641 gcttttcgga caggtacaaa gcgacattat ccatcgttcc gctttctggc agttaccgtt
     2701 atggctgagt tctccggcaa accgggcctc cggtgaaatg gtttttgatg cagagcgtga
     2761 gatttatttc ccgcagcgcc ccccccgtcc gcagggtgaa gtttatcgtc gttacgatcc
     2821 acgcattcgc aggatgctga gtttccgcat tgccgatccc gtttctgatg cagaacgttt
     2881 cactcgctgg atgaacgatc cgcgcgttga gtatttctgg gagcaaagtg gctcactgga
     2941 ggttcagatc gcctatctgg aacgccagct caccagtaaa catgcattcc cgctgattgg
     3001 ttgtttcgac gatcggccgt tcagttattt cgaaatctac tgggcggcgg aagaccgcat
     3061 tggtcgccac tattcgtggc agccctttga ccgtggcctg catctgctgg ttggtgaaca
     3121 gcaatggcgc ggagcccact atgtgcaaag ctggctgcgc ggggtgacac attacctgct
     3181 gctgaatgag ccacgtacgc agcgcacagt actggagcca cgcaccgata accagcgcct
     3241 gttccgccat cttgagcctg cgggataccg gacaattaaa gagttcgact tcccacataa
     3301 acgctcgcgc atggtgatgg cggatcgtca tcacttcttc acggaggtcg gtctgtaatg
     3361 aatcacaaag actgggattt ggtcaaccgc cgcctggtgg caaaaatgtt gtctgagctg
     3421 gagtatgagc aggttttcca cgcggaatct cagggcgatg accgctactg cattaacctg
     3481 ccgggagcac aatggcgctt catcgctgaa cgtggtatct ggggctggct ctggattgat
     3541 gctcaaactc tgcgctgcgc ggacgagcca gtactggctc agacgctgct gatgcagcta
     3601 aagcaggtac tgtcaatgag cgatgcaacc gttgctgagc atatgcagga tttgtatgcc
     3661 acgctgctgg gcgacctgca actactgaaa gcccgtcgcg ggctgagcgc cagtgacctg
     3721 attaatctta atgccgaccg cctgcaatgc ctgctgagcg gtcatcctaa attcgttttt
     3781 aataaaggtc gccgtggctg gggtaaagag gcgctggaac gatatgcgcc agagtatgcc
     3841 aacaccttca gactgcactg gctggcggta aaacgtgaac atatgatctg gcgctgtgat
     3901 aacgagatgg atattcatca gttgttgacg gccgcaatgg atccgcagga gtttgcccgc
     3961 ttcagtcagg tctggcagga aaacggactg gatcataact ggctgccgct gccggtacat
     4021 ccgtggcagt ggcagcaaaa aatcgctacc gacttcatcg ctgattttgc cgaaggcagg
     4081 atggtgtctc tcggcgagtt tggcgaccag tggctcgccc agcagtcgct gcgtaccctg
     4141 accaacgcca gtcgccgggg cgggctggat atcaagctgc cgctgaccat ctacaacacc
     4201 tcatgctacc gggggatccc tggcagatac atcgctgccg gaccactggc ttcacgctgg
     4261 ctacaacagg tttttgcgac cgacgccacc ctagtgcaaa gcggcgcagt gatacttggt
     4321 gaaccggctg caggctatgt ctcccatgaa ggctatgccg cgcttgcccg ggctccctat
     4381 cgctaccagg aaatgcttgg tgttatctgg cgggagaatc cgtgccgctg gctgaaaccg
     4441 gatgaaagtc cggttctgat ggcaacactg atggagtgcg acgaaaacaa tcagccgctg
     4501 gcaggcgcat atatagaccg ctccgggctg gacgctgaaa cctggcttac gcaactgttc
     4561 cgggtggtcg tggttcctct gtatcacctg ctttgccgct acggtgtcgc gcttattgca
     4621 catggacaaa atataactct cgccatgaaa gagggggttc cacagcgtgt tctgctgaaa
     4681 gacttccagg gcgatatgcg actggtgaaa gaagagttcc ccgaaatgga ctctttgcct
     4741 caggaggttc gtgatgttac atcccgcctg agtgcggact acttaatcca tgatttgcag
     4801 acgggtcact tcgtgacagt actgcgtttt atttcgccac tgatggttcg tcttggcgta
     4861 cctgaaaggc gattttatca actgctggca gcagtgttga gtgattacat gaaaaaacat
     4921 ccacaaatgt cagagcgttt tgcgcttttc tcacttttca ggccacaaat cattcgcgtg
     4981 gtgctgaacc cggtaaaact gacctggcct gatctggatg gcggcagccg catgctgccg
     5041 aattaccttg aggatctgca aaatccgctg tggctggtaa ctcaggaata tgaatcatga
     5101 aaaaaagtgt cgattttatt ggtgtaggga cagggccatt taatctcagc attgctgcgt
     5161 tgtcacatca gatcgaagaa ctggactgtc tcttctttga tgaacatcct catttttcct
     5221 ggcatccggg tatgctggta ccggattgtc atatgcagac cgtctttctg aaagatctgg
     5281 tcagtgctgt tgcacctaca aatccctaca gttttgttaa ctatctggtg aagcacaaaa
     5341 agttctatcg cttccttaca agcagactac gtacagtatc ccgtgaagag ttttctgact
     5401 acctccgctg ggctgctgaa gatatgaata acctgtattt cagtcatacc gttgaaaaca
     5461 ttgatttcga taaaaaacgt cgattgtttc tggtgcaaac cagccaggga gaatattttg
     5521 cccgcaatat ctgccttggt acaggaaaac aaccttattt accaccctgt gtgaagcata
     5581 tgacacaatc ctgtttccat gccagtgaaa tgaatcttcg tcggccggac cttagtggaa
     5641 aacggataac cgtggttggt ggaggacaga gtggtgcaga cctgttcctt aatgcattac
     5701 gcggggaatg gggagaagcg gcggaaataa actgggtctc ccggcgtaat aattttaacg
     5761 cactggatga ggctgctttt gctgatgagt attttacacc tgaatatatt tcaggcttct
     5821 ccggactgga ggaagatatt cgccatcagt tactggatga gcagaaaatg acatcggatg
     5881 gcatcactgc cgattcttta ctgaccattt atcgtgagtt gtaccaccgt tttgaagttc
     5941 tgagaaaacc aagaaatatc cgtctgctac ccagccgctc ggtaacaact ctggaaagta
     6001 gtggtcctgg ctggaagttg ctgatggagc atcatctgga tcagggcagg gagagcctgg
     6061 aaagtgatgt ggtgattttc gccacaggtt accgttctgc gttgccacaa atacttccct
     6121 cactgatgcc cctgatcacc atgcacgata agaacacctt taaagtgcgt gatgacttca
     6181 ctctggaatg gagtggcccg aaagagaaca acatcttcgt ggtcaacgcc agtatgcaaa
     6241 cccatggcat cgccgaaccc cagctcagcc tgatggcatg gagatctgca cgtattctta
     6301 atcgcgtaat gggacgtgat ttattcgatc tcagtatgcc gcccgccctg attcagtggc
     6361 gcagcggcac ctagggaaaa cgcagccgga ggctgcttct ttaactcgct acacagcatc
     6421 tttgggctga ttttttccgc ccgtatggag gaataatgat gataagcaaa aagtatacgc
     6481 tttgggctct caacccactg cttcttacca tgatggcgcc agcagtcgct caacaaaccg
     6541 atgatgaaac gttcgtggtg tctgccaacc gcagcaatcg caccgtagcg gagatggcgc
     6601 aaaccacctg ggttatcgaa aacgccgaac tggaacagca gattcagggc ggcaaagagc
     6661 ttaaagacgc actggctcag ctgatccctg gccttgacgt cagcagccgg agccgcacca
     6721 actacggtat gaatgtgcgt ggccgcccgc tggtcgtgct ggttgacggc gtgcgtctca
     6781 actcttcacg taccgacagc cgacaactgg actctataga tccttttaat atcgaccata
     6841 ttgaagtgat ctccggtgcg acgtccctgt acggcggcgg cagtaccggt ggcctgatca
     6901 acatcgtgac caaaaaaggc cagccggaaa ccatgatgga gtttgaggct ggcaccaaaa
     6961 gtggctttag cagcagtaaa gatcacgatg aacgcattgc cggagctgtc tccggcggaa
     7021 atgagcatat ctccggacgt ctttccgtgg catatcagaa atttggcggc tggtttgacg
     7081 gtaacggcga tgccaccttg cttgataaca cccagaccgg cctgcagtac tccgatcggc
     7141 tggacatcat gggaactggt acgctgaaca tcgatgaatc ccggcagctt cagttgatca
     7201 cacagtacta taaaagccag ggcgacgacg attacgggct taatctcggg aaaggcttct
     7261 ctgccatcag agggaccagc acgccattcg tcagtaacgg gctgaattcc gaccgtattc
     7321 ccggcactga gcggcatttg atcagcctgc agtactctga cagcgctttt ctgggacagg
     7381 agctggtcgg tcaggtttac taccgcgatg agtcgttgcg attctacccg ttcccgacgg
     7441 taaatgcgaa caaacaggtg acggctttct cttcgtcaca gcaggacacc gaccagtacg
     7501 gcatgaaact gactctgaac agcaaaccga tggacggctg gcaaatcacc tgggggctgg
     7561 atgctgatca tgagcgcttt acctccaacc agatgttctt cgacctggct caggcaagcg
     7621 cttccggagg gctgaacaac aagaagattt acaccaccgg gcgctatccg tcgtatgaca
     7681 tcaccaacct ggcggccttc ctgcaatcag gctatgacat caataatctc tttaccctca
     7741 acggtggcgt acgctatcag tacactgaaa acaagattga tgatttcatc ggctacgcgc
     7801 agcaacggca gattgccgcc gggaaggcta catccgccga cgccattcct ggcggctcag
     7861 tcgattacga caacttcctg ttcaacgccg gtctgctgat gcacatcacc gaacgccagc
     7921 aggcatggct caacttctcc cagggcgtgg agctgccgga cccgggtaaa tactatggtc
     7981 gcggcatcta tggtgctgca gtgaacggcc atcttcctct aacaaagagt gtgaacgtca
     8041 gcgacagcaa gctggaaggc gtgaaagtcg attcttatga gctgggctgg cgctttactg
     8101 gcaataatct gcgtacccaa atcgcggcct actattcgat ttctgataag agcgtggtgg
     8161 cgaataaaga tctgaccatc agcgtggtgg acgacaaacg ccgtatttac ggcgtggaag
     8221 gtgcggtgga ctacctgatt cctgatactg actggagtac cggagtgaac ttcaacgtgc
     8281 tgaaaactga gtcgaaagtg aacggtacct ggcagaaata cgatgtgaag acagcaagcc
     8341 catcaaaagc gacagcctac attggctggg caccggaccc gtggagtctg cgcgtgcaga
     8401 gcaccacctc ctttgacgtg agcgacgcgc agggctacaa ggtcgatggc tataccaccg
     8461 tggatctgct cggcagttat cagcttccgg tgggtacact cagcttcagc attgaaaacc
     8521 tcttcgaccg tgactacacc actgtctggg ggcagcgtgc accactgtac tacagcccgg
     8581 gttacggccc agcgtcactg tacgactaca aaggcagggg ccgaaccttt ggtctgaact
     8641 actctgtgct gttctgaccg gtattccttt acaacaaagg tacgctgata tcaacatggc
     8701 cgctgacagc caagttgata tcatataata cacgacataa tctgtagtca gggaggatag
     8761 actct
//
LOCUS       DAPOAV010000134         8416 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.135, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000134 DAPOAV010000000
VERSION     DAPOAV010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8416
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.135"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(168..1832)
                     /gene="glnS"
                     /locus_tag="RN951_004052"
     CDS             complement(168..1832)
                     /gene="glnS"
                     /locus_tag="RN951_004052"
                     /EC_number="6.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase"
                     /protein_id="HDX2528973.1"
                     /translation="MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGH
                     AKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSD
                     YFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEK
                     MRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCI
                     SDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNL
                     LVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIRE
                     DLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRAD
                     FREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADG
                     RKVKGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSL
                     KDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE"
     gene            complement(2035..3981)
                     /gene="nagE"
                     /locus_tag="RN951_004053"
     CDS             complement(2035..3981)
                     /gene="nagE"
                     /locus_tag="RN951_004053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetyl glucosamine transporter subunit
                     IIABC"
                     /protein_id="HDX2528974.1"
                     /translation="MNILGFFQRLGRALQLPIAVLPVAALLLRFGQPDLLNVAFIAQA
                     GGAIFDNLALIFAIGVASSWSKDSAGAAALAGAVGYFVLTKAMVTINPEINMGVLAGI
                     ITGLVGGAAYNRWSDIKLPDFLSFFGGKRFVPIATGFFCLVLAAIFGYVWPPVQHAIH
                     AGGEWIVSAGALGSGIFGFINRLLIPTGLHQVLNTIAWFQIGEFTNAAGTVFHGDINR
                     FYAGDGTAGMFMSGFFPIMMFGLPGAALAMYFAAPKERRPMVGGMLLSVAVTAFLTGV
                     TEPLEFLFMFLAPLLYLLHALLTGISLFVATLLGIHAGFSFSAGAIDYALMYNLPAAS
                     QNVWMLLVMGVIFFAIYFVVFSLVIRMFNLKTPGREDKEDEIVTEEANSNTEEGLTQL
                     ATNYIAAVGGTDNLKAIDACITRLRLTVADSARVNDTMCKRLGASGVVKLNKQTIQVI
                     VGAKAESIGDAMKKVVARGPVAAASAEATPATAAPVAKPQAVPNAVSIAELVSPITGD
                     VVALDQVPDEAFASKAVGDGVAVKPTDKIVVSPAAGTIVKIFNTNHAFCLETEKGAEI
                     VVHMGIDTVALEGKGFKRLVEEGAQVSAGQPILEMDLDYLNANARSMISPVVCSNIDD
                     FSGLIIKAQGHVVAGQTPLYEIKK"
     gene            4314..5114
                     /gene="nagB"
                     /locus_tag="RN951_004054"
     CDS             4314..5114
                     /gene="nagB"
                     /locus_tag="RN951_004054"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008805656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDX2528975.1"
                     /translation="MRLIPLTTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGT
                     PMTTYKALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAE
                     NINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIK
                     TLTHDTRVANSRFFDNDVNQVPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEG
                     CVNHMWTISCLQLHPKAIMVCDEPSTMELKVKTLRYFNELEAENIKGL"
     gene            5174..6322
                     /gene="nagA"
                     /locus_tag="RN951_004055"
     CDS             5174..6322
                     /gene="nagA"
                     /locus_tag="RN951_004055"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDX2528976.1"
                     /translation="MYALTQGRIFTGHEFLDDHAVVIADGLIKSVCPVAELPPEIEQR
                     SLNGAILSPGFIDVQLNGCGGVQFNDTAEAVSVETLEIMQKANEKSGCTNYLPTLITT
                     SDELMKQGVRVMREYLAKHPNQALGLHLEGPWLNLVKKGTHNPNFVRKPDAALVDFLC
                     ENADVITKVTLAPEMVPAEVISKLANAGIVVSAGHSNATLKEAKAGFRAGITFATHLY
                     NAMPYITGREPGLAGAILDEADIYCGIIADGLHVDYANIRNAKRLKGDKLCLVTDATA
                     PAGANIEQFIFAGKTIYYRNGLCVDENGTLSGSSLTMIEGVRNLVEHCGIALDEVLRM
                     ATLYPARAIGVEKRLGTLAAGKVANLTAFTPDFKITKTIVNGNEVVTQ"
     gene            6331..7551
                     /gene="nagC"
                     /locus_tag="RN951_004056"
                     /gene_synonym="nagR"
     CDS             6331..7551
                     /gene="nagC"
                     /locus_tag="RN951_004056"
                     /gene_synonym="nagR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NagC"
                     /protein_id="HDX2528977.1"
                     /translation="MTPGGQAQIGNVDLVKQLNSAAVYRLIDQYGPISRIQIAEQSQL
                     APASVTKITRQLIERGLIKEVDQQASTGGRRAISIVTETRNFHAIGVRLGRHDATITL
                     FDLSSKVLAEEHYPLPERTQQTLEHALLNAIAQFIDSYQRKLRELIAISVILPGLVDP
                     DSGKIHYMPHIQVENWGLVEALEERFKVTCFVGHDIRSLALAEHYFGASQDCEDSILV
                     RVHRGTGAGIISNGRIFIGRNGNVGEIGHIQVEPLGERCHCGNFGCLETIAANAAIEQ
                     RVLNLLKQGYQSRVPLDDCTIKTICKAANKGDSLASEVIEYVGRHLGKTIAIAINLFN
                     PQKIVIAGEITKADKVLLPAIESCINTQALKAFRTNLPVVRSELDHRSAIGAFALVKR
                     AMLNGILLQHLLEN"
     gene            7599..8351
                     /gene="nagD"
                     /locus_tag="RN951_004057"
     CDS             7599..8351
                     /gene="nagD"
                     /locus_tag="RN951_004057"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide monophosphatase NagD"
                     /protein_id="HDX2528978.1"
                     /translation="MTIKNVICDIDGVLMHDNVAVPGAAEFLHGIMDKGLPLVLLTNY
                     PSQTGQDLANRFATAGVDVPDSVFYTSAMATADFLRRQEGKKAYVVGEGALIHELYKA
                     GFTITDVNPDFVIVGETRSYNWDMMHKAAYFVANGARFIATNPDTHGRGFYPACGALC
                     AGIEKISGRKPFYVGKPSPWIIRAALNKMQAHSEETVIVGDNLRTDILAGFQAGLETI
                     LVLSGVSSLDDIDSMPFRPSWIYPSVAEIDVI"
BASE COUNT         2065 a         2214 c         2137 g         2000 t
ORIGIN      
        1 gcgtgaacgc cttatccggc ctacaaaagc acgcaaactc aatatattgc agagatcatg
       61 taggcctgat aagcgtagcg catcaggcaa tttagcgttt gaaactgttt gtctgttcct
      121 tgccggatgc gacgtaaacg ccccatccgg catagcgaaa cttaaaatta ctcgcctact
      181 ttcgcccagg tatcacgcag cccaacggtg cggttaaata ccggtttttc cgccgtagaa
      241 tggcggctat cgaggcagaa gtaaccttca cgctcaaact ggaatgcttt acccgcaacc
      301 gcatctttca gcgacggttc agcaaagccc tgtttgatca ccagcgattc cgggttaatc
      361 accgacagga aatcatccgc agcacctggg ttaggcacgc tgaacagacg gtcatacaaa
      421 cggatttcaa ccggcagcgc atgtgccgcg ctcacccagt gaataacacc tttgacttta
      481 cgaccatctg ccggatcttt gcttaaggta tcggcgtcat aagtacagaa gatggtggtg
      541 atattacctt cggcatcttt ctcgacgcgt tctgccttaa tcacataagc attacgcaga
      601 cgcacttctt tacccagcac cagacgtttg tactgcttgt tagcttcttc gcggaaatcg
      661 gcgcgatcaa tccaaatctc accgctaaac ggcacctgac ggctgcccat ttccggtttg
      721 ttcggatggt tcggcatggt aaccatttcg ccttcgccct gatagttttc gataaccagt
      781 ttcaccggat cgataaccgc cattgcgcgc ggcgcatttt cgttgagatc ttcacggatg
      841 caggattcca gcgacgccat ctcaatggtg ttgtcctgct tggtcacgcc gatgcgtttg
      901 cagaactcac gaatagaagc cgcagtgtaa ccacgacgac gcagaccgga aatggtcggc
      961 atacgcgggt catcccagcc ttcaacgtgc ttgtcggtca ccagcaggtt caacttacgc
     1021 ttggacatca cggtgtattc cagattcagg cgcgagaact catactggcg cgggtgaaca
     1081 ggaatcgtga tgttgtccag tacccagtcg tacagacgac ggttgtcctg gaactcaagc
     1141 gtacacagag agtgcgtaat accttccagg gcatcgctga tgcagtgggt gaagtcgtac
     1201 atcgggtaga tgcaccactt gttgccagtc tggtggtgtt cagcaaattt aatacggtac
     1261 agcaccggat cgcgcatcac gataaacggt gaagccatgt cgattttcgc acgcaggcag
     1321 gctttacctt cttcaaaacc accggcacgc attttttcga acagcgccag gttctcttca
     1381 acgctgcggt cgcggtacgg gctgttttta cccggttgcg tcagggtgcc gcggtattcg
     1441 cggatctgtt ccggcgtcag ttcatcaacg tacgccaggc ctttattgat cagttcgatc
     1501 gcataggcgt ggagctgatc aaaataatcg gaggagtaac ggacgttacc agaccagtga
     1561 aaacctaacc actctacgtc gtttttgatc gactcaacat actcgatatc ttcttttacc
     1621 gggttagtgt cgtcgaaacg caggttgcac tggcctttat agtcctgggc gatcccgaag
     1681 ttcaggcaga tagatttcgc atggccaata tgcagatagc cattcggctc cggcgggaaa
     1741 cgggtgtgta ctgtggtgtg cttaccactg gccagatctt catcgatgat ctgacggata
     1801 aagttagtcg ggcgggcttc tgcctcactc atcgtggatt cctcaaagcg taaacaacgt
     1861 ataacggcgt atgatcttat aagcgggaca ggctgacaac tgttagtttt ttaaaattga
     1921 taatctaaca aggattatgg ggatgattga tgaaaaaaaa agcggcagag aagatctcca
     1981 ccgcttgtca ttgttggatg cgacgctcaa gcgtcgcatc aggcataaag cagattactt
     2041 tttgatttca tacagcggtg tttgacccgc cacaacatgg ccctgagctt taatgatcaa
     2101 gccactgaaa tcgtcgatat tgctgcaaac caccgggcta atcatcgagc gggcgttagc
     2161 gttcaggtaa tccagatcca tttccagaat cggttgccct gcgcttacct gcgcaccctc
     2221 ttccaccaga cgtttaaagc ctttaccttc cagcgctacg gtgtcgatac ccatatggac
     2281 gacgatctcc gcgccttttt cggtttccag gcagaacgcg tggttggtgt tgaagatttt
     2341 cacgattgtc cctgcggctg gtgatacgac gattttatct gtcggtttca ccgccacacc
     2401 gtcacccacc gctttgctgg cgaatgcttc gtcaggaacc tgatccagtg ccacgacatc
     2461 accggtaatc ggcgatacca gctccgcgat agataccgcg tttggtacag cctgcggttt
     2521 tgctacaggc gcggcagttg ccggagttgc ttcagctgac gcagcggcta ccggaccacg
     2581 ggcaacgact ttcttcatcg catcgccgat ggattctgct ttcgcgccaa caatcacctg
     2641 aatagtctgt ttgttcagtt tcactacccc agaagcaccc agacgtttac acatcgtatc
     2701 gttaacgcgg gcagagtcag ccactgtaag gcgcagacgg gtgatacagg cgtcaatcgc
     2761 tttcaggttg tcagtgccgc caaccgcagc aatatagttg gttgccagtt gagtcagacc
     2821 ttcttcagtg ttgctgttgg cttcttcagt aacgatctcg tcttctttat cttcacgacc
     2881 cggcgttttc aggttgaaca tgcggataac caaactgaac accacgaagt agatagcgaa
     2941 gaagataacg cccatcacca gcagcatcca gacgttctgg ctggcggccg gcaggttata
     3001 catcaacgcg tagtcgatag cccccgcaga gaaagagaag cccgcgtgga tacccagcag
     3061 cgttgccaca aacaggctga taccggtcag cagtgcgtgc aggaggtaca gcagcggagc
     3121 aaggaacatg aacaggaatt ccagcggctc agtcacaccg gtcaggaacg cagtaacagc
     3181 aacagaaagc agcataccgc caaccatcgg acgacgctct ttcggtgctg cgaagtacat
     3241 cgccagcgcc gcacccggca gaccgaacat catgatcggg aagaagccgg acatgaacat
     3301 ccccgcggtg ccgtcaccgg catagaagcg gttaatgtca ccgtggaaaa ccgtacccgc
     3361 cgcgttggtg aattcaccaa tctggaacca ggcgatggtg ttcagtacct gatgcagacc
     3421 ggttgggatc agcagacggt tgatgaaacc aaagataccg gaacccagcg cgcccgcaga
     3481 aacgatccac tcgccgcctg catggatagc gtgctgtacc ggcggccaga cgtaaccaaa
     3541 aatggccgcc agcaccaggc agaagaatcc ggtggcaatc ggcacaaagc gtttgccgcc
     3601 gaagaagctc aggaagtccg gcagtttaat atcggaccaa cggttatagg ctgcgccacc
     3661 aaccagaccg gtaatgatac ccgccagtac acccatgtta atttctgggt tgatggtcac
     3721 catcgctttg gttaacacaa agtaacctac cgcacccgcc agcgccgccg caccagcgct
     3781 gtctttcgac cagctggatg ccacaccgat ggcgaagatt aatgcgaggt tatcaaaaat
     3841 cgcaccgccc gcctgggcaa taaacgcaac gttaagtaaa tctggctgac cgaatcgcag
     3901 caacagtgcc gccaccggca gcaccgcgat agggagctgt aacgccctac cgagtcgctg
     3961 gaaaaaacct aaaatattca tcttattccc cctacgagaa ccctatttgg ctcgtttcaa
     4021 gccgtatttt tattttgctg caaattgtac tgccgatgtt ctgtaatcag attgttagat
     4081 catctgctac agagtgtgtg aaaatttaat tcgtatcgca aattaaacgc gtgtcttttg
     4141 tgagttttgt caccaaatat cgttatcatc actccctttt actggctaaa ccagaaaact
     4201 tattttatca ttcaaaaaat caggtcggat tgacgcctgt ctgcgcaaat ccaggttacg
     4261 cttaaagatg cctaatccgc caacggctta cattttactt attgaggtga ataatgagac
     4321 tgatccccct gactaccgct gaacaggtcg gcaaatgggc tgctcgccat atcgtcaatc
     4381 gtatcaatgc gttcaaaccg actgccgatc gtccgtttgt actgggcctg ccgactggcg
     4441 gcacgccgat gaccacctat aaagcgttag tcgaaatgca taaagcaggc caggtcagct
     4501 ttaagcacgt tgtcaccttc aacatggacg aatatgtcgg tctgccgaaa gagcatccgg
     4561 aaagctacta cagctttatg caccgtaatt tcttcgatca cgttgatatt ccagcagaaa
     4621 acatcaacct tctcaacggc aacgccccgg atatcgacgc cgagtgccgc cagtatgaag
     4681 aaaaaatccg ttcttacgga aaaattcatc tgtttatggg cggtgtaggt aacgacggtc
     4741 atattgcatt taacgaaccg gcgtcttctc tggcttctcg tactcgtatc aaaaccctga
     4801 ctcatgacac tcgcgtcgca aactctcgtt tctttgataa cgatgttaat caggtgccaa
     4861 aatatgccct gactgtcggt gttggtacac tgctggatgc cgaagaagtg atgattctgg
     4921 tgctgggtag ccagaaagca ctggcgctgc aggccgccgt tgaaggttgc gtgaaccata
     4981 tgtggaccat cagctgtctg caactgcatc cgaaagcgat catggtgtgc gatgaacctt
     5041 ccaccatgga gctgaaagtt aagactttaa gatatttcaa tgaattagaa gcagaaaata
     5101 tcaaaggtct gtaattgtta tccctgccct ggctccttgc tcagggcaat attttttaaa
     5161 atcgggggtc agaatgtatg cattaaccca gggccggatc tttaccggcc acgaatttct
     5221 tgatgaccac gcggttgtta tcgctgatgg cctgattaaa agcgtctgtc cggtagcgga
     5281 actgccgcca gagatcgaac aacgttcact gaacggggcc attctctccc ccggttttat
     5341 cgatgtgcag ttaaacggct gcggcggcgt acagtttaac gacaccgctg aagcggtcag
     5401 cgtggaaacg ctggaaatca tgcagaaagc caatgagaaa tcaggctgta ctaactatct
     5461 gccgacgctt atcaccacca gcgatgagct gatgaaacag ggcgtgcgcg ttatgcgcga
     5521 gtacctggca aaacatccga atcaggcgtt aggtctgcat ctggaaggtc cgtggctgaa
     5581 tctggtaaaa aaaggcaccc ataatccgaa ttttgtgcgt aagcctgatg ccgcgctggt
     5641 cgatttcctg tgtgaaaacg ccgacgtcat taccaaagtg accctggcac cggaaatggt
     5701 tcctgcggaa gtcatcagca aactggcaaa tgccgggatt gtggtttctg ccggtcactc
     5761 caacgcgacg ttgaaagaag caaaagccgg tttccgcgcg gggattacct ttgccaccca
     5821 tctgtacaac gcgatgccgt atattaccgg tcgtgaacct ggcctggcgg gcgcgatcct
     5881 cgacgaagct gacatttatt gcggtattat tgctgatggc ctgcatgttg attacgccaa
     5941 cattcgcaac gctaaacgtc tgaaaggcga caaactgtgt ctggttactg acgccaccgc
     6001 gccagcaggt gccaacattg aacagttcat ttttgcgggt aaaacaatat actaccgtaa
     6061 cggactttgt gtggatgaga acggtacgtt aagcggttca tccttaacca tgattgaagg
     6121 cgtgcgtaat ctggtcgaac attgcggtat cgcactggat gaagtgctac gtatggcgac
     6181 gctctatccg gcgcgtgcga ttggcgttga gaaacgtctc ggcacactcg ccgcaggtaa
     6241 agtagccaac ctgactgcat tcacacctga ttttaaaatc accaagacca tcgttaacgg
     6301 taacgaggtt gtaactcaat aagagaaagt atgacaccag gcggacaagc tcagataggt
     6361 aatgttgatc tcgtaaaaca gcttaacagc gcggcggttt atcgcctgat tgaccagtac
     6421 gggccaatct cgcggattca gattgccgag caaagccagc ttgcccccgc cagcgtaacc
     6481 aaaattacgc gtcagcttat cgaacgcggg ctgatcaaag aagttgatca gcaggcctcc
     6541 accgggggcc gccgcgctat ctccatcgtc accgaaaccc gcaatttcca cgcaatcggc
     6601 gtacggcttg gtcgtcatga cgccaccatc actctgtttg atctcagcag caaagtgctg
     6661 gcagaagaac attacccgct gccggaacgt acccagcaaa cgctggaaca tgccctgttg
     6721 aatgccattg ctcagtttat tgatagctac cagcgcaaac tgcgcgagct gatcgcgatt
     6781 tcggtgatcc tgccagggct tgttgacccg gacagcggca aaattcatta catgccgcat
     6841 attcaggtag aaaactgggg gctggtagaa gctctggaag aacgttttaa agtgacctgt
     6901 ttcgttggtc acgatatccg tagtctggcg ctggcggagc actacttcgg tgcaagtcag
     6961 gattgcgaag actccattct ggtgcgtgtc catcgcggaa ccggggccgg gattatctct
     7021 aacgggcgca tttttattgg ccgcaacggc aacgtcggtg aaattggcca tattcaggtc
     7081 gaaccgctgg gtgaacgctg ccactgcggc aactttggct gcctggaaac tatcgctgcc
     7141 aacgctgcca ttgaacaacg ggtgttgaat ctgttaaagc agggctacca gagccgcgtg
     7201 ccgctggacg actgcaccat caaaactatc tgcaaagccg cgaacaaagg cgatagtctg
     7261 gcgtcggaag taattgagta tgtcggtcgt catctgggta aaaccatcgc cattgctatc
     7321 aacttattta atccgcaaaa aattgttatt gccggtgaaa tcaccaaagc cgataaagtg
     7381 ctgctccctg ctattgaaag ctgcattaat acccaggcgc tgaaggcgtt tcgcactaat
     7441 ctgccggtgg tacgttctga gctggatcac cgctcggcaa tcggcgcttt tgcgctggta
     7501 aaacgcgcca tgctcaacgg tattttgctc cagcatttgc tggaaaatta atgtgctttt
     7561 atagtggcgc ttattgttgt caatattctg ggtagtccat gaccattaaa aatgtaattt
     7621 gcgatatcga cggcgtgctg atgcacgata acgtcgccgt accgggtgca gcggaatttt
     7681 tgcacgggat tatggataaa ggcctgccgc tggtgttgct gaccaactat ccttcgcaga
     7741 ctgggcaaga tctggcgaac cgctttgcca ccgcaggtgt cgatgtacct gacagcgtgt
     7801 tttatacctc tgcgatggcg actgccgatt tcctgcgtcg ccaggaaggc aagaaagcgt
     7861 atgtggtggg cgaaggcgca ctgattcatg aactgtacaa agccggtttc actattaccg
     7921 atgtgaaccc tgatttcgtg attgttggcg aaacgcgttc ctacaactgg gacatgatgc
     7981 ataaagcagc ctatttcgtc gctaacggtg cacgttttat cgccaccaat ccggacaccc
     8041 acgggcgcgg tttttatccc gcttgtggcg cgttgtgtgc agggattgag aaaatctccg
     8101 ggcgcaaacc gttctatgtt ggtaagccca gcccgtggat catccgcgca gcattaaaca
     8161 aaatgcaggc gcattcggaa gaaacggtga ttgtcggcga taacctgcgt accgatattc
     8221 tggccggctt ccaggcaggt ctggagacga ttctggtgct ttctggtgtt tcgtcgctcg
     8281 acgatatcga cagtatgcct ttccgcccca gctggattta cccgtcagtc gctgaaatcg
     8341 acgttatctg aatagcaacc acgtctgcgg acgtggttgg ctctgatgac aaacgccaaa
     8401 ctgcctgatg cgctac
//
LOCUS       DAPOAV010000135         8412 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.136, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000135 DAPOAV010000000
VERSION     DAPOAV010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8412
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.136"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..385
                     /locus_tag="RN951_004058"
     CDS             <1..385
                     /locus_tag="RN951_004058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528979.1"
                     /translation="MIKANVWHLYKEWIRSDDVSPIFIETEDNLRTFNTNELTRNDNI
                     FILFSSVDDGPVMVVSSQRLHDMLNPTKDTNWNSTYIYKSRHEMLPVNLTQETLFSSK
                     SHGKYALFPIFTASWRAHRIMNKGV"
     gene            608..1105
                     /gene="ubiC"
                     /locus_tag="RN951_004059"
     CDS             608..1105
                     /gene="ubiC"
                     /locus_tag="RN951_004059"
                     /EC_number="4.1.3.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709881.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate lyase"
                     /protein_id="HDX2528980.1"
                     /translation="MSHPALTQLRALRYFKEIPALEPQLLDWLLLEDSMTKRFEQQGK
                     TVSVTMIREGFVEQNEIPEELPLLPKESRYWLREILLCADGEPWLAGRTVVPVSTLSG
                     PELALQKLGKTPLGRYLFTSSTLTRDFIEIGRDAGLWGRRSRLRLSGKPLLLTELFLP
                     ASPLY"
     gene            1118..1990
                     /gene="ubiA"
                     /locus_tag="RN951_004060"
     CDS             1118..1990
                     /gene="ubiA"
                     /locus_tag="RN951_004060"
                     /EC_number="2.5.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybenzoate octaprenyltransferase"
                     /protein_id="HDX2528981.1"
                     /translation="MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVP
                     QLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVV
                     LVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAA
                     VSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGIL
                     QIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREACFKAFMNNNYVG
                     LVLFLGLAMSYWHF"
     gene            complement(2145..4568)
                     /gene="plsB"
                     /locus_tag="RN951_004061"
     CDS             complement(2145..4568)
                     /gene="plsB"
                     /locus_tag="RN951_004061"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418465.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsB"
                     /protein_id="HDX2528982.1"
                     /translation="MSGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYV
                     LPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGTLLPRYVFIHGGPRVFTYYTPKEESI
                     KLFHDYLDLHRSNPNLDVQMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLG
                     RDSFVRFSPSVSLRRMADEHGTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFN
                     KLLASRAIAKAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWN
                     RLYQGINVHNAERVRQLAHDGHELVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGIN
                     LNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTG
                     RLLDPKTGTLSMTIQAMLRGGTRPITLIPIYIGYEHVMEVGTYAKELRGATKEKESLP
                     QMLRGLSKLRNLGQGYVNFGEPMPLMTYLNQHVPDWRESIDPIEAVRPAWLTPTVNNI
                     AADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLNCYLDLMRNVPYSTDST
                     VPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVLPSLMA
                     AIVTQHRHISRDVLMEHVNVLYPMLKAELFLRWDRDELPDVIDALANEMQRQGLITLQ
                     DDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSANPSINRGTLEKESRTVAQRLS
                     VLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAETMKVYQLLAELITSDVRLT
                     IESATQGEG"
     gene            4739..5107
                     /gene="dgkA"
                     /locus_tag="RN951_004062"
     CDS             4739..5107
                     /gene="dgkA"
                     /locus_tag="RN951_004062"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDX2528983.1"
                     /translation="MANNTTGFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLAVV
                     IACWLDVDAITRVLLISSVMLVMIVEILNSAIEAVVDRIGSEYHELSGRAKDMGSAAV
                     LIAIIVAVITWCILLWSHFG"
     gene            5217..5825
                     /gene="lexA"
                     /locus_tag="RN951_004063"
     CDS             5217..5825
                     /gene="lexA"
                     /locus_tag="RN951_004063"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repressor LexA"
                     /protein_id="HDX2528984.1"
                     /translation="MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAE
                     EHLKALARKGVIEIVSGASRGIRLLQEEEEGLPLVGRVAAGEPLLAQQHIEGHYQVDP
                     SLFKPNADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKK
                     QGNKVELLPENSEFKPIVVDLRQQSFTIEGLAVGVIRNGDWL"
     gene            5898..7223
                     /gene="dinF"
                     /locus_tag="RN951_004064"
     CDS             5898..7223
                     /gene="dinF"
                     /locus_tag="RN951_004064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter DinF"
                     /protein_id="HDX2528985.1"
                     /translation="MAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVY
                     LGGVAVGATATSFLFMLLLFLRMSTTGLTAQAYGAKNPQALARTLVQPLLLALGAGAL
                     IALLRTPIIDLALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA
                     PVILLVVGNILNIVLDVWLVMGLHMNVQGAALATVIAEYATLLIGLLMVRKILKLRGI
                     SGEMLKTAWRGNFRRLLALNRDIMLRSLLLQLCFGAITVLGARLGSDIIAVNAVLMTL
                     LTFTAYALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGIVALLFSVVYLLAGE
                     HIIALLTSLTQIQQLADRYLIWQVILPVVGVWCYLLDGMFIGATRATEMRNSMAVAAA
                     GFALTLLTLPWLGNHALWLALTVFLALRGLSLAAIWRRHWRNGTWFAAT"
     gene            7339..7548
                     /locus_tag="RN951_004065"
     CDS             7339..7548
                     /locus_tag="RN951_004065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HDX2528986.1"
                     /translation="MNKDEAGGNWKQFKGKVKEQWGKLTDDDMTIIEGKRDQLVGKIQ
                     ERYGYQKDQAEKEVVDWETRNEYRW"
     gene            complement(7590..8105)
                     /gene="zur"
                     /locus_tag="RN951_004066"
     CDS             complement(7590..8105)
                     /gene="zur"
                     /locus_tag="RN951_004066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418470.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc uptake transcriptional repressor Zur"
                     /protein_id="HDX2528987.1"
                     /translation="MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISA
                     YDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFI
                     CDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEACRHPEQCQH
                     DHSVQVKKKPR"
BASE COUNT         1938 a         2038 c         2272 g         2164 t
ORIGIN      
        1 tatgatcaaa gcaaatgttt ggcatcttta taaagagtgg attcgtagtg atgatgtttc
       61 acctatattt atagaaactg aagataattt aagaaccttt aacacgaatg aattaacacg
      121 aaacgataat atctttatcc tgttctcctc agtcgatgat gggccagtta tggtggtaag
      181 ctcccagcgc ttacatgata tgttgaatcc tacaaaagat accaattgga attccacgta
      241 tatctacaaa tccagacatg agatgttgcc tgttaatctt actcaggaaa cacttttcag
      301 ctccaaatct catggtaaat atgcgctttt ccccattttt actgcgagtt ggcgagctca
      361 tcgtataatg aataagggtg tttaagtaaa ggaaaacatc accgttcctg gcatcctgga
      421 cggtgatgcc cctacggttg ccctcgccag cacgggcatc ggtaaagcgt aaggttcaac
      481 atcgttttac cacttcatgc gattgttgcg tttttgttgc gtattagatc acttaatttg
      541 ctttacatct cccgtaaaca cttttctgcg atacaatgcc tttacgttat gtaacggaga
      601 gttcggcatg tcacaccccg cgttaacgca actgcgtgcg ctgcgctatt ttaaagagat
      661 ccctgccctg gaaccgcaac tgctcgactg gctgttgctg gaggattcca tgacaaaacg
      721 ttttgaacag cagggaaaaa cggtaagcgt gacgatgatc cgcgaagggt ttgtcgagca
      781 gaatgaaatc cccgaagaac tgccgctgct gccgaaagag tctcgttact ggttacgtga
      841 aattttgtta tgtgccgatg gtgaaccgtg gcttgccggt cgtaccgtcg ttcctgtgtc
      901 aacgttaagc gggccggagc tggcgttaca aaaattgggt aaaacgccgt taggacgcta
      961 tctgttcaca tcatcgacat taacccggga ctttattgag ataggccgtg atgccggact
     1021 gtgggggcga cgttcccgcc tgcgattaag cggtaaaccg ctgttgctaa cagaactgtt
     1081 tttaccggcg tcaccgttgt actaagagga aaaaaatatg gagtggagtc tgacgcagaa
     1141 taagctgctg gcgtttcatc gcttaatgcg tacggataag ccaattggcg cgttactgct
     1201 gctctggcca acattatggg cgttgtgggt ggcgacaccg ggcgttcctc agctctggat
     1261 cctggcggta tttgtcgcgg gtgtctggct gatgcgcgct gctggatgtg tggtgaatga
     1321 ttatgctgac cgaaagtttg atggtcatgt taagcgcacg gcgaaccgac cacttcccag
     1381 cggcgcggta acagagaaag aggcgcgcgc gctgtttgtc gtgctggtac tgatttcgtt
     1441 tttactggtg ctgacgctga atacgatgac cattctgttg tcgattgccg cgctagcgct
     1501 ggcgtgggtg tacccgttta tgaagcggta tacccatcta ccgcaagtgg tgctgggcgc
     1561 ggcgtttggc tggtcgattc caatggcttt tgccgctgtg agtgagtcgg tgccattgag
     1621 ttgctggtta atgttcctcg ccaatattct ctgggcggtg gcttacgaca cgcagtatgc
     1681 gatggttgac cgcgatgatg atgtgaagat tggcattaaa tccacggcaa tcctgttcgg
     1741 ccaatacgat aaattgatta ttggtatttt gcagattggc gtactggcac tgatggcgat
     1801 catcggtgag ttaaatggct taggctgggg atattactgg tcaattctgg tggctggcgc
     1861 gctgtttgtt tatcaacaaa aactgattgc caaccgcgag cgtgaagcct gctttaaagc
     1921 atttatgaat aataactatg ttggtctggt actattttta gggctggcaa tgagttactg
     1981 gcatttctga tgatgtaaaa aagccggatg atcatccggc tttcttctgg gttgcctgat
     2041 gcgcggcgct tctcaggcct acacaacaca tcgcaattta ttgaatttgc agattatgga
     2101 aggccggata aggcgttttc gccgcatccg gcaattctct ctgattaccc ttcgccctgc
     2161 gtcgcactct caatcgtcaa acgcacgtct gatgtaatca actccgccag caactgataa
     2221 accttcatcg tttctgccgg ttcggcatcg ccgctatcgc tgatataccc ttcatcacgc
     2281 agtgtcagca ccagagaact gaacaccgcc ttgtcgaaga actccggcgc gttgatgccg
     2341 tgcagcacgg agagacgttg cgcgacggtg cggctctctt tctccagcgt accgcggttg
     2401 atcgacgggt tggcactcaa caaccagaag gtgatggcat aacgttgcag cgtttcgcgc
     2461 gcgcctgcgg ccagcagctg tagcgtgcga gaatgcgccg ggttgatatg caactcatca
     2521 tcttgcaggg taatcagccc ctgacgttgc atctcatttg ccagcgcatc aataacgtcc
     2581 ggcaactcgt cgcgatccca gcgcaggaac agctccgctt tcagcattgg gtaaagcaca
     2641 ttgacgtgct ccatcaatac gtcgcgggag atgtggcgat gctgggtgac gattgccgcc
     2701 atcagcgaag gcagcaccaa catatgcgca atgttgttgc gatagtaggt catcagcacc
     2761 gcttgctcgc gcggcagaat gatgatgtcg ccgattgtgt ctttctcgac ttcaaacttg
     2821 ttcatttgca gcgcgtgatc gataagctcg ctggcgctgg ctgaaggaac ggtagagtcc
     2881 gtggagtagg gcacgttgcg catcagatcc aggtagcagt tgagttgctc ggttaactgc
     2941 tcgcgggtga gtgagcgctg acgtgatgcc agtagcgcag tacagcacag gttcatggcg
     3001 tttgccgcgc ctgcgttgtt aatgcgtacc atcagatcgg cagcaatatt attgaccgtc
     3061 ggcgttaacc atgccggacg caccgcttcg atgggatcga tagattcacg ccagtcaggt
     3121 acatgctggt taaggtaggt catcaacggc attggttcac cgaagttgac gtaaccctga
     3181 ccgagattac gcagcttgct taaaccgcgc agcatctgcg gcaggctctc tttctctttc
     3241 gtcgcgccgc gcagttcttt ggcgtaagta cccacttcca tgacgtgctc ataaccgata
     3301 tagatcggaa tcagcgtaat cggacgcgtg ccgccacgca gcatcgcctg aatggtcatc
     3361 gacagcgtac cagttttcgg atccagcaaa cgccccgtac gggaacgacc gccttccacg
     3421 aagtactcga cggaataacc acggctgaac agttcgccga gatactcccg gaaaacggtg
     3481 gaataaagtt tattgccttt aaacgtacgg cgaataaaga acgcccccag acggcggaaa
     3541 atcggcccgg caggccagaa attcaggttg atcccggcgg cgatatgcgg cggcaccagc
     3601 ccctggtgat acagcacgta agaaagcagc aggtagtcca tgtgactgcg gtggcaaggc
     3661 acatatacca gctcatgacc gtcgtgggcc agctggcgaa cgcgctcagc gttatggacg
     3721 ttgatgccct ggtaaagtcg gttccaggtg aagcccagaa tacggtcagt caggcgaatc
     3781 atctcgtaag agaaattcgc cgcaatctct tccatcagtg caatcgcgtt ctgctgcgct
     3841 ttttcatggg agattttttt gctgcgcgct tcatcttcta ccgctttggc aatggcgcgg
     3901 gaggcgagca gcttattaaa cagatcctga cgagcaggca aacgtgggcc tacggcagcc
     3961 agacgttgac gggcaaagtg catacgcgcc acgcgcgcca gtttctgagc gatagtttta
     4021 tccgtgccgt gttcatccgc catacggcgc agcgaaactg acggcgagaa acgcacaaaa
     4081 ctgtcgcgac cgagccacag tacagcgaaa aatttctgta cgccgttaag catacgcagc
     4141 ggcgggttca cttcgccttt ttcacgcccc ggcgcgcgac caaacatcac cgacactggc
     4201 accatctgca catccagatt tgggttgcta cggtgcaaat cgagatagtc gtggaacagc
     4261 ttaatagact cttctttcgg cgtgtaatag gtgaacacac gcggcccgcc gtgaatgaac
     4321 acatagcgcg gcagtagcgt gccgtcgatt tccagcggct ctaacgggtc aggcaagtca
     4381 tgtgccagac actgggcgcg caacgtcagc aaatctgctt tcgagttgta cggtaaaacg
     4441 tacataattg gacgagaggt atccagcccc agttccgggg caggatctgc cggaatagac
     4501 ttgcttttta ccaggatgct taatggtaaa ttcagtaatt tgtagtaaat tcgtggccag
     4561 ccggacataa acgatgtaaa gcctctggtt aataatgcaa atgcgcggca aggatagcag
     4621 aaagtcatgg gaaattctgt ggtatccgct catgtttcgc gcggcgctac gcaaacccga
     4681 atcatcggat ttaacggtac actgatattg acgctcataa tgtaaaaagg ttctttcaat
     4741 ggccaataat accactggat tcacccgaat tatcaaagct gctggctatt cctggaaagg
     4801 tttacgcgct gcatggatca acgaagcggc attccgtcag gaaggcgtag cggtattgtt
     4861 ggcggtggtc atcgcctgct ggctggatgt ggacgcgatt acccgcgtgc tgcttatcag
     4921 ctccgtgatg ctggtgatga ttgtggaaat cctcaatagc gccatcgaag cagtggttga
     4981 ccgaattggc tctgaatacc atgagctttc cggacgcgca aaagatatgg gatccgctgc
     5041 ggtgctgatt gccattatcg tcgccgtgat tacctggtgc attctgttat ggtcgcattt
     5101 tggataaccc ttccagaatt cgataaatct ctggtttatt gtgcagttta tggttccaaa
     5161 atcgcctttt gctgtatata ctcacagcat aactgtatat acacccaggg ggcggaatga
     5221 aagcgttaac ggccaggcaa caagaggtgt ttgatctcat ccgtgatcac atcagccaga
     5281 caggtatgcc gccgacgcgt gcggaaatcg cgcagcgttt ggggttccgt tccccaaacg
     5341 cggctgaaga acatctgaag gcgctggcac gcaaaggcgt tattgaaatt gtttccggcg
     5401 catcacgcgg gattcgtctg ttgcaggaag aggaagaagg gttgccgctg gtaggtcgtg
     5461 tggctgccgg tgaaccactt ctggcgcaac agcatattga aggtcattat caggtcgatc
     5521 cttccttatt caagccgaat gctgatttcc tgctgcgcgt cagcgggatg tcgatgaaag
     5581 atatcggcat tatggatggt gacttgctgg cagtgcataa aactcaggat gtacgtaacg
     5641 gtcaggtcgt tgtcgcacgt attgatgacg aagttaccgt taagcgcctg aaaaaacagg
     5701 gcaataaagt cgaactgttg ccagaaaata gcgagtttaa accaattgtc gttgaccttc
     5761 gtcagcagag cttcaccatt gaagggctgg cggttggggt tattcgcaac ggcgactggc
     5821 tgtaacatat ctctgagacc gcgatgccgc ctggcgtcgc ggtttgtttt tcatctctct
     5881 tcatcaggct tgtctgcatg gcattcctca cttcatctga taaagcactc tggcatctcg
     5941 ccttacccat gattttctcc aatatcaccg ttccgttgct gggactggtc gatacggcgg
     6001 taattggtca tcttgatagc ccggtttatt tgggcggcgt ggcggttggt gcaacggcga
     6061 ccagctttct ctttatgctg ttgctgtttt tacgcatgag caccaccggg ctgactgcgc
     6121 aggcttatgg tgccaaaaat cctcaggcat tagcccgtac gctggtgcaa ccgttgctgt
     6181 tggcgttggg ggctggggcg ttaattgcgc tgctgcgtac gccgattatc gatctggcgc
     6241 tgcatattgt tggcggtagt gaggcagtcc tggaacaggc gcggcgcttt cttgaaatcc
     6301 gctggttaag cgcaccggcg tcgctggcga atctggtatt actcggttgg ttactcggcg
     6361 tgcaatatgc ccgtgcgcca gtaattttgt tagtggtcgg caatatcctc aacattgtgc
     6421 tggatgtctg gctggtgatg gggctgcata tgaacgtgca gggcgcggcg ctggcgacgg
     6481 ttattgcgga atatgcaaca ttgctgattg gtctgctaat ggtgcgtaaa atcctcaaac
     6541 tacgcggaat ttccggcgaa atgctgaaaa ctgcctggcg aggaaacttc cgtcgcttgc
     6601 tggcgcttaa ccgcgatatc atgctgcgtt cgctgttgtt gcaactctgt ttcggcgcga
     6661 tcaccgtact tggcgcgcga ctggggagtg acattatcgc tgttaacgcg gttctgatga
     6721 cgctactcac ctttaccgcc tatgcgctgg atggttttgc ctacgcggtt gaagcgcact
     6781 ccggtcaggc atacggtgcg cgcgacggta gccagttgct ggatgtctgg cgggcagcgt
     6841 gccgccagtc ggggatcgta gcgttactgt tttcggtggt ttatttgctg gctggggaac
     6901 acatcattgc gttactgacg tcgttaaccc agattcagca gctggctgac cgctatctta
     6961 tctggcaggt gattttgccg gtggttggcg tctggtgtta tctgctggac ggcatgttta
     7021 taggcgcaac gcgtgccacc gaaatgcgta acagtatggc ggtggccgcc gcaggttttg
     7081 cgctgacgct ccttacgctg ccgtggctgg gtaatcatgc tttgtggctg gcattaaccg
     7141 tctttctggc gttgcgcggg ctttctctgg cggctatctg gcggcgtcac tggcgcaatg
     7201 gtacctggtt tgccgcaacg tgacggttaa aaattctgaa taaataatcc taagccaaat
     7261 tgctgactac acttaatctc acgttcagaa gaaaagtgaa cgtactctca ttcacaacct
     7321 aacgatgagg tcttgattat gaataaagat gaagccggcg gtaactggaa acagtttaaa
     7381 ggtaaagtga aagagcaatg gggcaaactg accgatgatg atatgacgat cattgaaggt
     7441 aaacgtgatc aactggtcgg taaaatccag gaacgttatg gttatcagaa agatcaggca
     7501 gaaaaagagg tcgtggattg ggaaacccgc aatgaatatc gctggtaatt aatccctcct
     7561 gcccgacgtg tacaaggatg tacgccctct taacgcggtt tctttttcac ctgcacagag
     7621 tgatcatgct ggcactgttc aggatgacga cacgcttcca cttctacaca tgccgcacag
     7681 agcccatgtg cttcaatcac attatgccgc agggcaaacc ccatttttgc cgccagcgta
     7741 tgcataatgt cttccacgcc ttctgcacac tcttctttca ctgcgccgca gcgatcgcaa
     7801 ataaacatgg ctgacgtatg ggtgggctga tcgaacagat gacagagcac ataactgttg
     7861 gtggattcca ccttatgcac aaaaccttgc tcaagcagaa aatccagcgc gcgataaacc
     7921 gttggcggct tggcttgcgg ttcagcttcg cgcagtaaat caagcagatc ataagcgctg
     7981 atagcgccat cctgcagact catcaggcgc aacacttcca ggcgctgtgg ggtcaggcgc
     8041 acattacgct gcgcgcagat tttttcagcc tgcgctaata actcctgcgt tgtggtcttt
     8101 tccatcgggc acctcaaagt gggggttaag aatgtcctta ctttaccatg ttccaggaaa
     8161 aacaccgaga acccttattg ttgccgtaat gttgattttc tgttttgtag gtaaggtgtt
     8221 atgttgcctt gtcgtaccat tatcaacacg ataataatta ataattcatt tttaaataaa
     8281 ttgcttcaag ttaactcgct atttatttaa ctgggtttaa acgcatacct gtagttcaga
     8341 aattatgagc gatttttgat agtgaccaga tggcaaaaga attataagga ggacacggta
     8401 cgacaaaaaa gg
//
LOCUS       DAPOAV010000136         8250 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.137, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000136 DAPOAV010000000
VERSION     DAPOAV010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8250
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.137"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(667..1914)
                     /locus_tag="RN951_004067"
     CDS             complement(667..1914)
                     /locus_tag="RN951_004067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide MFS transporter"
                     /protein_id="HDX2528988.1"
                     /translation="MALNIPFRNAYYRFASSYSFLFFISWSLWWSLYAIWLKGHLGLT
                     GTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWCMSFILVLTGPFMIYVYEPLL
                     QSNFSVGLILGALFFGLGYLAGCGLLDSFTEKMARNFHFEYGTARAWGSFGYAIGAFF
                     AGIFFSISPHINFWLVSLFGAVFMMINMCFKDKDHQCVAADAGGVKKEDFIAVFKDRN
                     FWVFVIFIVGTWSFYNIFDQQLFPVFYAGLFESHDVGTRLYGYLNSFQVVLEALCMAI
                     IPFFVNRVGPKNALLIGVVIMALRILSCALFVNPWIISLVKLLHAIEVPLCVISVFKY
                     SVANFDKRLSSTIFLIGFQIASSLGIVLLSTPTGILFDHAGYQTVFFAISGIVCLMLL
                     FGIFFLSKKREQIVMETPVPSAI"
     gene            complement(1986..2900)
                     /locus_tag="RN951_004068"
     CDS             complement(1986..2900)
                     /locus_tag="RN951_004068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoimidazole riboside kinase"
                     /protein_id="HDX2528989.1"
                     /translation="MSAKVWVLGDAVVDLLPESDGRLLPCPGGAPANVAVGIARLGGT
                     SGFIGRVGDDPFGALMQRTLLTEGVDITYLKQDEWHRTSTVLVDLNDQGERSFTFMVR
                     PSADLFLETTDLPCWRHGEWLHLCSIALSAEPSRTSAFTAMTAIRHAGGFVSFDPNIR
                     EDLWQDEHLLRLCLRQALQLADVVKLSEEEWRLISGKTQNDRDICALAKEYEIAMLLV
                     TKGAEGVVVCYRGQVHHFAGMSVNCVDSTGAGDAFVAGLLTGLSSTGLSTDEREMRRI
                     IDLAQRCGALAVTAKGAMTALPCRQELE"
     gene            3116..4549
                     /gene="cscA"
                     /locus_tag="RN951_004069"
     CDS             3116..4549
                     /gene="cscA"
                     /locus_tag="RN951_004069"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708234.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HDX2528990.1"
                     /translation="MTQSRLHAAQNALAKLHEHRGNTFYPHFHLAPPAGWMNDPNGLI
                     WFNDRYHAFYQHHPMSEHWGPMHWGHATSDDMIHWQHEPIALAPGDDNDKDGCFSGSA
                     VDDNGVLSLIYTGHVWLDGAGNDDAIREVQCLATSRDGIHFEKQGVILTPPEGIMHFR
                     DPKVWREADTWWMVVGAKDPGNTGQILLYRGSSLREWTFDRVLAHADAGESYMWECPD
                     FFSLGDQHYLMFSPQGMNAEGYSYRNRFQSGVIPGMWSPGRLFAQSGHFTELDNGHDF
                     YAPQSFLAKDGRRIVIGWMDMWESPMPSKREGWAGCMTLARELSESNGKLLQRPVHEA
                     ESLRQQHQSVSPRTISNKYVLQENAQAVEIQLQWALKNSDAEHYGLQLGTGMRLYIDN
                     QSERLVLWRYYPHENLDGYRSIPLPQRDTLALRIFIDTSSVEVFINDGEAVMSSRIYP
                     QPEERELSLYASHGVAVLQHGALWLLG"
     gene            complement(4557..5615)
                     /locus_tag="RN951_004070"
     CDS             complement(4557..5615)
                     /locus_tag="RN951_004070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDX2528991.1"
                     /translation="MDLASDVCFCYSARFTANGLGMASLKDVARLAGVSMMTVSRVMH
                     NAESVRPATRDRVLQAIQTLNYVPDLSARKMRAQGRKPSTLAVLAQDTATTPFSVDIL
                     LAIEQTASEFGWNSFLINIFSEDDAARAARQLLAHRPDGIIYTTMGLRHITLPESLYG
                     ENIVLANCVADDPALPSYIPDDYTAQYESTQHLLAAGYRQPLCFWLPESALATGYRRQ
                     GFEQAWRDAGRDLAEVKQFHMATGDDHYTDLASLLNAHFKPGKPDFDVLICGNDRAAF
                     VAYQVLLAKGVRIPQDVAVMGFDNLVGVGHLFLPPLTTIQLPHDIIGREAALHIIEGR
                     EGGRVTRIPCPLLIRCST"
     gene            5795..6013
                     /locus_tag="RN951_004071"
                     /pseudo
     CDS             5795..6013
                     /locus_tag="RN951_004071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416866.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine transporter DsdX"
     gene            6031..7359
                     /gene="dsdA"
                     /locus_tag="RN951_004072"
     CDS             6031..7359
                     /gene="dsdA"
                     /locus_tag="RN951_004072"
                     /EC_number="4.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine ammonia-lyase"
                     /protein_id="HDX2528992.1"
                     /translation="MENAKMNSLIAQYPLVKDLVALKETTWFNPGTTSLAEGLPYVGL
                     TEQDVQDAHARLSRFAPYLAKAFPETAATGGIIESELVAIPAMQKRLEKEYQQPISGQ
                     LLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLDDDYSKLLSPEFKQFFSQ
                     YSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGV
                     AVEEGRKAAQSDPNCFFIDDENSRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYL
                     PCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNL
                     TAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMA
                     GPQRVCASVSYQQMHGFSAEQLRNTTHLVWATGGGMVPEEEMNQYLAKGR"
     gene            complement(7467..>8250)
                     /gene="emrY"
                     /locus_tag="RN951_004073"
     CDS             complement(7467..>8250)
                     /gene="emrY"
                     /locus_tag="RN951_004073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrY"
                     /protein_id="HDX2528993.1"
                     /translation="VIWESTSENPILDLSLFKSRNFTIGIVSITCAYLFYSGAIVLMP
                     QLLQETMGYNAIWAGLAYAPIGIMPLLISPLIGRYGNKIDMRLLVTFSFLMYAVCYYW
                     RSVTFMPTIDFTGIILPQFFQGFAVACFFLPLTTISFSGLPDNKFANASSMSNFFRTL
                     SGSVGTSLTMTLWGRRESLHHSQLTATIDQFNPVFNSSSQIMDKYYGSLSGVLNEINN
                     EITQQSLSISANEIFRMAAIAFILLTVLVWFAKPPFTAKGIG"
BASE COUNT         2340 a         2024 c         1895 g         1991 t
ORIGIN      
        1 aggtacttaa gtttgcttaa ctggaactta tagaagaata catatacgtt tttctatgtc
       61 attacttcgg atttgaggtt cgcaattttt acctaaaatc actcactcca gttcaggaac
      121 aatgtgttat atgatggtat ccttgatggt attaacttaa aataaaaaca ataaaaacca
      181 taaaatcaaa cacataaaaa atgattcgat tcctgcaggg acaccagata cccttcaaac
      241 gaaatctacc ttcaccccgt aaaagatagg tttggcagca cacttgcctt atatctactc
      301 atttttactg caacaggttg aaatctcagc actgtcagaa agcgctgatg actaaacagc
      361 cctgggccgg gcgatgtaac catcacacag aatcctgata gcgaaatatg gcgtgactcg
      421 atacttcact ccgcaatgca ttccttgatg aattcgcagg accgtgatac acgggacagg
      481 tcgctgaatg acgacaatgt cctggaaatc agcgaaccgc gcatctgaag tacatttgag
      541 cgactgtacc agaacatgaa tgaggcgttt ggattaggtg attattagca gggctaagca
      601 ctttagtatt attattttcc ggttgaggga tagggagata tcgacaacaa ccggaaaagt
      661 ttacgtctat attgctgaag gtacaggcgt ttccataact atttgctcgc gttttttact
      721 caagaagaaa atgccaaata gcaacatcag gcagacaata cccgaaattg cgaagaaaac
      781 tgtctggtag cctgcgtggt caaagagtat cccagtcggc gttgaaagca gcacaatccc
      841 aagcgaactg gcaatttgaa aaccaatcag aaagatcgtc gacgacaggc gcttatcaaa
      901 atttgccacg ctgtatttga agacggatat gacacaaagt ggaacctcaa tagcatgtaa
      961 cagcttcact aatgaaataa tccaggggtt aacgaacagc gcgcaggaaa ggatacgcaa
     1021 cgccataatc acaacaccga taagtaatgc attttttggc cctacccgat tcacaaagaa
     1081 aggaataatc gccatgcata gcgcttcgag taccacctgg aatgagttga gataaccata
     1141 caggcgcgtt cctacatcgt gtgattcgaa taaacctgca taaaagacag gaaaaagttg
     1201 ttgatcaaaa atgttataga aagaccacgt ccccacaata aatatgacga aaacccagaa
     1261 gtttcgatcc ttgaaaactg cgataaaatc ctcttttttt acccctcccg catccgccgc
     1321 tacgcactgg tgatccttat ctttaaaaca catgttgatc atcataaata cagcgccaaa
     1381 tagcgagacc aaccagaagt tgatatgggg actgatacta aaaaatatgc cggcaaagaa
     1441 cgcgccaata gcatagccaa aagatcccca ggcgcgcgct gttccatatt cgaaatgaaa
     1501 atttcgcgcc attttttcgg tgaagctgtc aagcaaaccg catcccgcca gataccccag
     1561 tccaaaaaag agcgccccca gaattagacc tacagaaaaa ttgctttgca gtaacggttc
     1621 ataaacgtaa atcataaacg gtccggtcaa gaccaggatg aaactcatac accagatgag
     1681 cggtttcttc agaccgagtt tatcctgaac gatgccgtag aacatcataa atagaatgct
     1741 ggtaaactgg ttgaccgaat aaagtgtacc taattccgtc cctgtcaacc ctagatgtcc
     1801 tttcagccaa atagcgtata acgaccacca cagcgaccag gaaataaaaa agagaaatga
     1861 gtaactggat gcaaaacgat agtacgcatt tctgaatgga atattcagtg ccataattac
     1921 ctgcctgtcg ttaaaaaatt cacgtcctat ttagagataa gagcgacttc gccgtttact
     1981 tctcactatt ccagttcttg tcgacatggc agcgctgtca ttgccccttt cgccgttact
     2041 gcaagcgctc cgcaacgttg agcgagatcg ataattcgtc gcatttctct ctcatctgta
     2101 gataatcccg tagaggacag acctgtgagt aacccggcaa cgaacgcatc tcccgccccc
     2161 gtgctatcga cacaattaac agacattcca gcaaaatggt gaacttgtcc tcgataacag
     2221 accaccacac cttctgcacc tttagtcacc aacagcatgg cgatctcata ctcttttgcc
     2281 agggcgcata tatcccgatc gttctgtgtt tttccactga taagtcgcca ttcttcttcc
     2341 gagagcttga cgacatccgc cagttgtagc gcctgccgca aacacaagcg gagcaaatgc
     2401 tcgtcttgcc atagatcttc acgaatatta ggatcgaagc tgacaaaacc tccggcatgc
     2461 cggatcgccg tcatcgcagt aaatgcgctg gtacgcgaag gctcggcaga caacgcaatt
     2521 gaacagagat gtaaccattc gccatgtcgc cagcagggca agtctgtcgt ctctaaaaaa
     2581 agatcggcac tggggcggac cataaacgta aatgaacgtt ccccttgatc gttcagatcg
     2641 acaagcaccg tggatgtccg gtgccattca tcttgcttca gatacgtgat atcgactccc
     2701 tcagttagca gcgttctttg cattaacgca ccaaaaggat catcccccac ccgacctata
     2761 aacccacttg ttccgcctaa tctggcgatt cccaccgcaa cgttagctgg cgcgccgcca
     2821 ggacaaggca gtagccgccc gtctgattct ggcaagagat ctacgaccgc atcccctaaa
     2881 acccatactt tggctgacat ttttttccct taaattcatc tgagttacgc atagtgataa
     2941 acctcttttt cgcaaaatcg tcatggattt actaaaacat gcatattcga tcacaaaacg
     3001 tcatagttaa cgttaacatt tgtgatattc atcgcattta tgaaagtaag ggactttatt
     3061 tttataaaag ttaacgttaa caattcacca aatttgctta accaggatga ttaaaatgac
     3121 gcaatctcga ttgcatgcgg cgcaaaacgc cctagcaaaa cttcatgagc accggggtaa
     3181 cactttctat ccccattttc acctcgcgcc tcctgccggg tggatgaacg atccaaacgg
     3241 cctgatctgg tttaacgatc gttatcacgc gttttatcaa catcacccga tgagcgaaca
     3301 ctgggggcca atgcactggg gacatgccac cagcgacgat atgatccact ggcagcatga
     3361 gcctattgcg ctagcgccag gagacgataa tgacaaagac gggtgttttt caggtagtgc
     3421 tgtcgatgac aatggtgtcc tctcacttat ctacaccgga cacgtctggc tcgatggtgc
     3481 aggtaatgac gatgcaattc gcgaagtaca atgtctggct accagtcggg atggtattca
     3541 tttcgagaaa cagggtgtga tcctcactcc accagaagga atcatgcact tccgcgatcc
     3601 taaagtgtgg cgtgaagccg acacatggtg gatggtagtc ggggcgaaag atccaggcaa
     3661 cacggggcag atcctgcttt atcgcggcag ttcattgcgt gaatggacct tcgatcgcgt
     3721 actggcccac gctgatgcgg gtgaaagcta tatgtgggaa tgtccggact ttttcagcct
     3781 tggcgatcag cattatctga tgttttcccc gcagggaatg aatgccgagg gatacagtta
     3841 ccgaaatcgc tttcaaagtg gcgtaatacc cggaatgtgg tcgccaggac gactttttgc
     3901 acaatccggg cattttactg aacttgataa cgggcatgac ttttatgcac cacaaagctt
     3961 tttagcgaag gatggtcggc gtattgttat cggctggatg gatatgtggg aatcgccaat
     4021 gccctcaaaa cgtgaaggat gggcaggctg catgacgctg gcgcgcgagc tatcagagag
     4081 caatggcaaa cttctacaac gcccggttca cgaagctgag tcgttacgcc agcagcatca
     4141 atctgtctct ccccgcacaa tcagcaataa atatgttttg caggaaaacg cgcaagcagt
     4201 tgagattcag ttgcagtggg cgctgaagaa cagtgatgcc gaacattacg gattacagct
     4261 cggcactgga atgcggctgt atattgataa ccaatctgag cgacttgttt tgtggcggta
     4321 ttacccacac gagaatttag acggctaccg tagtattccc ctcccgcagc gtgacacgct
     4381 cgccctaagg atatttatcg atacatcatc cgtggaagta tttattaacg acggggaagc
     4441 ggtgatgagt agtcgaatct atccgcagcc agaagaacgg gaactgtcgc tttatgcctc
     4501 ccacggagtg gctgtgctgc aacatggagc actctggcta ctgggttaac ataatatcag
     4561 gtggaacaac ggatcaacag cgggcaaggg atccgcgtca ctcttccccc ttcacgacct
     4621 tcaataatat gcaatgcagc ttcccgcccg ataatgtcat gtggaagctg aattgtggtc
     4681 agcggcggta aaaacagatg cccgacgcca accagattat caaagcccat tacggcgaca
     4741 tcctgcggga tacgtacccc cttcgccagg agaacctgat aagcgacaaa ggctgcgcga
     4801 tcgttaccac atatcagaac atcaaaatct ggtttgcccg gtttgaagtg ggcattgagt
     4861 aaacttgcga gatcggtgta gtgatcatca cctgttgcca tgtgaaattg tttcacctca
     4921 gccagatctc gtccagcatc acgccaggcc tgctcaaatc cctgccgacg ataccctgtt
     4981 gccaacgcac tttccggtag ccagaagcat aacggttgac gatagcccgc cgcgagcaaa
     5041 tgctgtgttg attcatattg tgcagtgtaa tcatcaggga tataactggg taacgctggg
     5101 tcatccgcca cacagttcgc caatacaata ttttcaccat acagagactc aggcagcgtg
     5161 atatgtcgca gccccattgt agtatagata atgccatccg gacggtgggc aagcagctga
     5221 cgtgccgcgc gggcagcgtc atcttcagaa aaaatattga ttaaaaaact attccagccg
     5281 aactcgctgg cggtttgctc aatggcaagc agaatatcaa cagagaaagg agtggtagcc
     5341 gtgtcctgcg ccagcacggc gagagtcgac ggcttacgtc cttgagcgcg catcttacgg
     5401 gcggaaagat caggaacata attcagggtc tggattgcct gcaatacgcg gtcacgcgtt
     5461 gcaggacgca cagattctgc attatgcatc acccgggaga ctgtcatcat cgacactccc
     5521 gccaggcgtg cgacatcctt taatgaagcc atacccaagc cgtttgccgt aaaacgggca
     5581 ctgtagcaga aacagacgtc actggcgaga tccaacgata ttctcaacgc cctatcaccc
     5641 aacacggcaa tacaataaaa aataacaata attgccggat aattgtactc aattccgcct
     5701 ctgttctcgc caacgagtaa ccatataggc aagtaagtaa aacatgccaa ctggcatcgc
     5761 caacctggag aagaaaatat aaatatggat cattgtgctg ccgctgtatc ccgacatcag
     5821 cccggaaatt attgcgattg ctatcggttc aggtgcaatt ggctgcacga tcgttacgga
     5881 ctcgcttttc tggctggtga agcaatattg cggcgctacg ctcaatgaaa catttaaata
     5941 ctatacgaca gcgacattta tcgcttcagt cgtcgctctg gcgggcacat tcctgctgtc
     6001 atttatcatc taagcgcaaa gagacgtact atggaaaacg ctaaaatgaa ctcgctcatc
     6061 gcccagtatc cgttggtaaa ggatctggtt gctcttaaag aaaccacctg gtttaatcct
     6121 ggcacgacct cattggctga aggtttacct tatgttggcc tgaccgaaca ggatgttcag
     6181 gacgcccatg cgcgcttatc ccgttttgca ccctatctgg caaaagcatt tcctgaaact
     6241 gctgccactg gggggattat tgaatcagaa ctggttgcca ttccagctat gcaaaaacgg
     6301 ctggaaaaag aatatcagca accgatcagc gggcaactgt tactgaaaaa agatagccat
     6361 ttgcccattt ccggctccat aaaagcacgc ggcgggattt atgaagtcct ggcacacgca
     6421 gaaaaactgg ctctggaagc ggggttgctg acgcttgatg atgactacag caaactgctt
     6481 tctccggagt ttaaacagtt ctttagccaa tacagcattg ctgtgggctc aaccggaaat
     6541 ctggggttat caatcggcat tatgagcgcc cgcattggct ttaaggtgac agttcatatg
     6601 tctgctgatg cccgggcatg gaaaaaagcg aaactgcgca gccatggcgt tacggtcgtg
     6661 gaatatgagc aagattatgg tgttgccgtc gaggaaggac gtaaagcagc gcagtctgac
     6721 ccgaactgtt tctttattga tgacgaaaat tcccgcacgt tgttccttgg gtattccgtc
     6781 gctggccagc gtcttaaagc gcaatttgcc cagcaaggtc gtatcgtcga tgctgataac
     6841 cctctgtttg tctatctgcc gtgtggtgtt ggcggtggtc ctggtggcgt cgcattcgga
     6901 cttaaactgg cgtttggcga tcatgttcac tgcttttttg ccgaaccaac gcactcccct
     6961 tgtatgttgt taggcgtcca tacaggatta cacgatcaga tttctgttca ggatattggt
     7021 atcgacaacc ttaccgcagc ggatggcctt gcagttggtc gcgcatcagg ctttgtcggg
     7081 cgggcaatgg agcgtctgct ggatggcttc tataccctta gcgatcaaac catgtatgac
     7141 atgcttggct ggctggcgca ggaagaaggt attcgtcttg aaccttcggc actggcgggt
     7201 atggccggac ctcagcgcgt gtgtgcatca gtaagttacc aacagatgca cggtttcagc
     7261 gcagaacaac tgcgtaatac cactcatctg gtgtgggcga cgggaggtgg aatggtgccg
     7321 gaagaagaga tgaatcaata tctggcaaaa ggccgttaat aacgtttcaa cgcagcatcg
     7381 caatcttttc cctgggtgag cgatgctgcc gatggcgcag acttaagatc cccggtctta
     7441 cccgctataa ccccctcctt ttatcatcac ccaatgcctt tcgctgtaaa cggcggtttc
     7501 gcaaaccaaa ccaaaaccgt aagtaagata aaagcaatag ccgccatacg gaaaatctca
     7561 tttgcagaaa tagaaagtga ctgctgggtt atttcattat taatttcatt aagaactcct
     7621 gaaagcgaac cataatattt atccataatt tgtgacgatg aattaaacac ggggttaaat
     7681 tgatcgatgg ttgctgtcaa ctgactatgg tgtaacgatt cgcgtcgtcc ccacagcgtc
     7741 attgtcaacg acgtaccaac tgatcctgac aaggtacgaa aaaaattact catactcgag
     7801 gcattggcaa atttattatc tggcaagcct gaaaacgaaa tcgttgttaa gggtaaaaag
     7861 aaacaggcaa cggcgaatcc ctgaaaaaac tgcggcaaaa tgatgcctgt aaaatcaatc
     7921 gttggcataa atgtcacaga acgccagtaa tagcaaaccg catacatcaa aaaactaaat
     7981 gtcactaaca accgcatgtc tattttgttg ccataacgtc ctatcaaagg tgaaattaat
     8041 agtggcatga tgccgatggg cgcataagca agtccggccc atatcgcatt ataccccatc
     8101 gtttcctgga gtaactgcgg cataagaacg atcgctccag agtaaaataa atacgcgcat
     8161 gtgatactca caataccaat ggtgaagtta cgggacttaa acaaactgag atcaagaatc
     8221 gggttctctg aggtcgactc ccaaatgact
//
LOCUS       DAPOAV010000137         8212 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.138, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000137 DAPOAV010000000
VERSION     DAPOAV010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8212
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.138"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            320..838
                     /locus_tag="RN951_004074"
     CDS             320..838
                     /locus_tag="RN951_004074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hcp family type VI secretion system effector"
                     /protein_id="HDX2528994.1"
                     /translation="MPTPCYISITGQTQGNITAGAFTADSVGNIYVQGHEDEMLVQEF
                     LHNVTVPTDPQSGQPAGQRAHKPFIFTVALNKAVPLMYNALASGEMLPTTELHWWRTS
                     VEGKQEHYFTTRLTDSTIVDMKLHMPHCQDPAKREFTQLLEVSLAYRKIEWEHVKSGT
                     SGADDWRAPLEA"
     gene            1048..3189
                     /locus_tag="RN951_004075"
     CDS             1048..3189
                     /locus_tag="RN951_004075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HDX2528995.1"
                     /translation="MSTGLRFTLEVDGLPPDAFAVVSFHLNQSLSSLFSLDLSLVSQQ
                     FLSLEFQQILDKMAYLTIWQGDDVQRRVKGVVTWFELGENDKNQKLYSMKVCPPLWRT
                     GLRQNFRIFQNEDIESILGTILQENGVTEWSPLFSEPHPSREFCVQYGETDYDFLCRM
                     AAEEGIFFYEEHAQKSTDQSLVLCDTVRYLPESFEIPWNPNTRTEVSTLCISQFRYSA
                     QIRPSSVVTKDYTFKRPGWAGRFDQEGQYQDYQRTQYEVYDYPGRFKGAHGQNFARWQ
                     MDGWRNNAEVARGTSRSPEIWPGRRIVLTGHPQANLNREWQVVASELHGEQPQAVPGR
                     SGSGTTLNNHFAVIPADRTWRPQPLLKPLVDGPQSAVVTGPAGEEIFCDEHGRVRVKF
                     NWDRYNPSNQDSSCWIRVAQAWAGTGFGNLAIPRVGQEVIVDFLNGDPDQPIIMGRTY
                     HQENRTPGSLPGTKTQMTIRSKTYKGSGFNELKFDDATGKEQVYIHAQKNMNTEVLNN
                     RTTDVINNHAEKIGNNQAITVTNNQIQNIGVNQIQTVGVNQVETVGSNQIIKVGSNQV
                     EKVGIIRALTVGVAYQTTVGGIMNTSVALLQSSQVGLHKSLMVGMGYSVNVGNNVTFS
                     VGKTMKENTGQTAVYSAGEHLELCCGKARLVLTKDGSIFLNGTHIHLEGESDVNGDAP
                     VINWNCGATQPVPDAPVPKDLPPGMPDMRQF"
     gene            3265..7497
                     /locus_tag="RN951_004076"
     CDS             3265..7497
                     /locus_tag="RN951_004076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001763881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HDX2528996.1"
                     /translation="MGGGKPAARQGDMTRKGLDIVQGSAGVLIGAPTGVACSVCPTKK
                     DSPNYGSPVNPLLGAKVLPVETDLALPGPLPFILFRAYSSYRTRTPAPVGVFGPGWKA
                     PFDIRLQVHERELILNDSGGRSIHFESLFPGEISYSRSESFWLARGGVLKQHKGHPLA
                     RLWRALPEAVRLSPHTYMMAVSTTGQWLILGWPERVPEADEVPPPEPPAYRVLTGVVD
                     GFGRTLTFHRAAEGDVAGAVTGVTDGAGRCFHLVLSTQAQRAEAFRKQRESSLSSPAG
                     PRSASSSQVFPDTLPAGTEYGADNGIRLEAVWLTHDPAYPDEQPTAPLARYTYTASGE
                     LRAVYDRSGTQVRGFTYDAEHAGRMVAHHYAGRPESRYRYDDTGRVTEQVNPEGLDYR
                     FEYGESRVIITDSLNRREVLYTEGEGGLKRVVKKEHADGSITRSEYDEAGRLKAQTDA
                     AGRRTEYRLHMASGKLTSVILPDGRTVRYGYNSQLQLTSVTYPDGLRSSRKYDRQGRL
                     AEETSRNGNITRWFYDFSRSGLPCAVEDGTGVRRRITRNRYGQLLAFTDCSGYTTRYE
                     YDQYGQQIAVHREEGISTYSSYNPRGQLISRKDAQGRETRYEYSAAGDLTATISPDGK
                     RSATEYDKRGRPVSVTEGGLTRSMGYDAAGRITVLTNENGSQSTFRYDPVDRLTEQRG
                     FDGRTQRYQYDLTGKLTQSEDEGLITLWHYDASDRITRRTVNGEPAEQWQYDDHGWLT
                     EISHLSEGHRVAVHYGYDDKGRLTGERQTVENPETGEMLWEHETGHAYSEQGLATRQE
                     PDGLQPVEWLTYGSGYLAGMKLGGTPLVEYTRDRLHRETARSFGGEAYELATAWNTSG
                     QLRSRHLNLPQLDRDYDWNDNGQLIRISGPQESREYRYSDTGRLTGVHTTAANLDIDI
                     PYATDPAGNRLPDPELHPDSTLTAWPDNRIAEDAHYVYRHDEYGRLAEKTDRIPEGVI
                     RMHDERTHHYHYDSQHRLVFYTRIQHGEPQVESRYLYDPLGRRTGKRVWRRERDLTGW
                     MSLSRKPEVTWYGWDGDRLTTIQTGTTRIQTVYQPGSFTPLLRIETENGEQAKARHRS
                     LAEVLQEDTGVTLPAELAVMLGRLERELRAGAVSAESEAWLAQCGLTAEQMAAQMEDA
                     YIPERRLHLYHCDHRGLPQALITPEGETAWCGEYDEWGNQLNEENPHHLYQPYRLPGQ
                     QYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGINLYTYPLVPIRYTDPLGLERVIS
                     VYGPPAPDRAGAETPLVLTDMTGGVTIYYDPETGDSMTFDSSNRIDRRSQRGAGDPYT
                     GEVVGCETNESGISAAYGTTKIYTTDTRARWLHGGGSSLRDPYAPRQGWKPTMGCTRA
                     QNEDVDELCKKVTSWMYSHPGERIRYERFKTR"
     gene            7475..7867
                     /locus_tag="RN951_004077"
     CDS             7475..7867
                     /locus_tag="RN951_004077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528997.1"
                     /translation="MNVLRHVNAINMGVCILIWVIGCANAKVLKRCILPAPDGGVEKL
                     SKPNLHGVIKKVDLNTNEAEIKIKEGGAVSFIFNEETLYFTVFGGDFIMDDLKKVKNT
                     EAWVWYKNCDSKNKNVAVELLQIYELHQ"
BASE COUNT         2028 a         2011 c         2539 g         1634 t
ORIGIN      
        1 caaaaattat caaaatgata attcagaaag gataaataca atatttattc atgattcagc
       61 tttggccatt ttatggaggc aatacggact ttgaacagtt gggtatggtt atccagatat
      121 atattattaa gttattgctg aataagagat ttaatgattt taaaaatagt ttttacgaca
      181 accgtaaatt ctagctcggt ttgtatgtaa aaaatactga aaatgatgcg gttccgtgaa
      241 gtgagctgca tctgcctgtc tgggattaac ggcaggtcat tgtaagtagt aattaaccac
      301 gttaacaagg agtttacaaa tgccaacacc gtgttatatc tccatcactg gtcagaccca
      361 gggaaatatt actgcaggtg catttaccgc tgattctgtc ggcaacatct atgtgcaggg
      421 gcacgaagac gagatgctgg tgcaggaatt cctgcataac gttactgtcc cgaccgatcc
      481 tcagtccggt cagcctgcgg gtcagcgtgc tcacaagcct ttcattttta ccgtggcgct
      541 gaacaaagcg gttccgctga tgtacaacgc actggcctcc ggcgaaatgc tgccaaccac
      601 tgaacttcac tggtggcgta cctctgtgga aggcaaacag gagcattatt tcactacccg
      661 cctgactgat tcgacgattg tcgatatgaa actgcatatg ccgcattgcc aggacccggc
      721 gaaacgcgag ttcacccagt tgctcgaagt ttcactggcc taccgcaaaa ttgaatggga
      781 acacgtcaaa tctggcacct ccggtgccga cgactggcgc gcaccgctgg aagcataagt
      841 taagccaaca gcatccggct atcaggccgg atgctgtttt tgtattacgc cgtagaaaga
      901 aaggttgtca gtaaggggtt acgttcacgg gagatggcgg ctgccggaaa cttcggcggt
      961 agcgtgcctg aacgcaagcg taacactgta ctgtcacagc cgctttaaca gcgaactgtc
     1021 tgtttttcct taaccccgga ggttgctatg tcaaccggat tacgtttcac gctggaagtg
     1081 gacggcctgc caccggatgc ttttgcggtg gtttcctttc atctgaacca gtcactctct
     1141 tcgctttttt ccctcgatct ctctctggtc agccagcagt ttctctccct tgaattccag
     1201 cagatcctcg acaaaatggc ctacctgacg atatggcagg gcgatgacgt acagcgccgg
     1261 gtgaaaggtg tggtgacctg gtttgaactg ggggagaacg acaaaaacca gaagctgtac
     1321 agcatgaagg tatgcccgcc gctgtggcgc acagggctgc gccagaactt ccgtatcttc
     1381 cagaatgagg acatcgaaag catcctcggc acgatattgc aggaaaacgg ggtgaccgag
     1441 tggagcccgc tgttcagcga gccacatcct tcccgtgagt tttgtgtcca gtacggtgag
     1501 actgattacg atttcctgtg ccggatggcg gcggaggaag gcatcttctt ttatgaggag
     1561 cacgcgcaaa aaagtaccga ccagagcctg gtcctgtgcg ataccgtgcg ttatctgccg
     1621 gagtcctttg agatcccctg gaatccgaac acccgtaccg aggtaagcac cctctgcatc
     1681 agccagtttc gctacagcgc acaaatccgc ccttcttccg tggtgaccaa agactacacc
     1741 tttaaacgac ccggctgggc agggcgtttt gatcaggaag gccagtacca ggattaccag
     1801 cgcacacagt atgaagtgta tgactacccc ggacgtttca agggtgctca cgggcagaac
     1861 tttgcccgct ggcagatgga tggctggcgc aacaacgcag aagtggcgcg cggaacaagc
     1921 cgttctccgg agatatggcc gggacggcga attgtgctga cggggcatcc gcaggcgaac
     1981 ctgaaccggg aatggcaggt ggtggcaagt gaactgcacg gcgagcagcc gcaggcggtg
     2041 ccgggacgca gtggttcagg aaccacgctg aataaccact ttgcggtaat accggcagac
     2101 cggacatggc ggccacagcc gttgctgaaa ccgctggtgg acggcccgca gagcgccgtc
     2161 gtgacgggac cggcaggcga ggaaatcttc tgtgatgaac atggccgcgt gcgggtgaaa
     2221 tttaactggg accgttataa cccgtcaaac caggacagtt catgctggat ccgtgtggca
     2281 caggcgtggg caggcaccgg attcggtaac ctggcgatac cgcgtgtggg tcaggaggtg
     2341 attgtggact tcctcaacgg cgatccggac cagccgatca ttatggggcg cacctaccac
     2401 caggaaaacc gcacacccgg cagcctgccg ggaacaaaga cgcagatgac cattcgttcg
     2461 aaaacctata agggcagcgg gtttaatgaa ctgaagtttg acgatgcgac agggaaagaa
     2521 caggtctaca tccacgcgca gaagaacatg aacaccgagg tgctgaataa ccgcaccact
     2581 gatgtgataa acaaccatgc cgaaaaaata ggtaacaacc aggcgatcac cgttaccaat
     2641 aaccagatcc agaacattgg cgttaatcag atacagacgg ttggtgtcaa ccaggtggaa
     2701 acggtgggta gtaaccagat tatcaaagtg ggatcaaacc aggttgaaaa ggtggggatc
     2761 attcgtgcgc tgacggtggg tgtggcttac cagacgacgg taggcggcat tatgaatacc
     2821 tcggtggcgt tgttgcagtc ctcacaggta gggctgcata aatcactgat ggtgggaatg
     2881 ggctacagcg tcaatgtggg gaataacgtc accttctcgg tgggcaagac gatgaaggaa
     2941 aacaccggac aaacagcagt ttattctgcc ggtgagcatc ttgaactctg ctgtggtaag
     3001 gcaaggctgg tgctgacgaa ggacggaagc atatttctca acggtacgca cattcatctg
     3061 gaaggggagt cggatgtgaa cggtgatgcg ccagtgatta actggaactg tggtgccaca
     3121 caacctgtac cggatgcgcc tgtgccgaaa gatttacccc ccggaatgcc ggatatgcgg
     3181 caattttgag tcaggtgcaa aaaattaaaa cggaactggt gcagtgacca gatgaaccat
     3241 attaaaagca gaaggaattg attcatgggc ggcggaaaac cggcggcgcg gcagggtgac
     3301 atgacccgca agggactgga tattgtgcag ggttcagcag gggtgctgat aggtgcgcca
     3361 accggtgtgg cctgctcggt gtgtcccaca aaaaaggaca gtccgaacta tggcagcccg
     3421 gtgaacccgc tactcggtgc gaaggttctg cctgttgaaa ccgacctggc actgcccggc
     3481 ccgctgccgt ttattctttt ccgcgcctac agcagctacc ggaccaggac gcccgcgcca
     3541 gtgggcgtgt ttggtcccgg ctggaaagcg cccttcgata tccgcttaca ggttcatgag
     3601 cgggaactga tactcaacga cagcggcggc aggagcattc actttgagtc gctgtttccc
     3661 ggcgagataa gctacagccg cagcgagtcg ttctggctgg caaggggcgg agtgctgaaa
     3721 caacacaaag gccatccgct tgcgcggctc tggcgggcgt tgccggaagc ggtccgtctg
     3781 agtccacaca cctatatgat ggctgtcagc acaaccgggc agtggctgat actcggctgg
     3841 ccggagcgtg tgccggaggc ggacgaggtg ccgccgccgg agccgcccgc ataccgggtg
     3901 ctgacgggcg tggtggacgg cttcgggcgg acgctgactt tccaccgggc ggcggagggt
     3961 gacgtggcgg gcgcggtgac gggggtgacg gacggtgcgg gccgctgttt tcacctggtg
     4021 ctgagcacac aggcgcagcg ggcagaagcc ttccgtaaac agcgcgagtc ttccttatct
     4081 tctccagccg gtccccgttc tgcttcctct tctcaggttt tccccgacac gctgcccgcc
     4141 ggtacagagt acggtgccga taacggtatc cggctggagg cggtgtggct gacacacgac
     4201 ccggcatacc cggatgaaca gccgactgcg ccgctggcgc gctacacgta cacggccagc
     4261 ggagaactgc gggcggtgta tgaccgcagc gggacgcagg ttcgcgggtt tacttatgat
     4321 gcggagcacg ccgggcggat ggtggcgcac cattatgcgg ggaggccgga gagccgctac
     4381 cggtatgatg ataccggtcg ggtgacggag caggtcaacc cggaggggct ggactaccgc
     4441 tttgagtacg gagagagccg ggtaatcatc acggacagcc tgaaccggcg ggaggtgctg
     4501 tacacggaag gcgagggtgg cctgaagcgg gtggtgaaga aggagcatgc cgacgggagc
     4561 atcacccgca gcgagtatga tgaggcgggg aggctgaagg cgcagacgga tgcggcgggg
     4621 cggcggacgg agtaccggct gcatatggcg tctggaaagc tgacttcagt gatactgccg
     4681 gacggcagga cggtgcggta tggctataac agccagttgc aactgacttc agtgacatat
     4741 ccggatggtt tacgcagcag ccggaaatat gaccgtcagg gccgactggc agaagagacc
     4801 tcgcgcaacg gtaacattac gcgctggttt tatgattttt cccgcagtgg cctgccctgt
     4861 gcggtggaag acggaaccgg ggtgaggcgg agaataacgc gaaaccgtta cggtcaactg
     4921 ctggccttta cggactgctc ggggtacacg acgcggtatg agtacgacca gtacggtcaa
     4981 caaatcgccg ttcaccggga agaaggcatc agcacttaca gcagttataa cccgcgtggc
     5041 caactgatca gtcggaagga tgcgcagggg cgtgaaaccc gttatgagta cagcgctgca
     5101 ggcgacctga cagcaacgat atcaccggac ggtaaacgca gcgccaccga atatgataaa
     5161 cgtgggcgtc cggtgagtgt gacggaaggt ggactgacgc gcagcatggg gtatgacgcc
     5221 gccgggcgca tcaccgtgct gactaacgag aacggcagcc agtccacgtt ccggtatgac
     5281 ccggtggaca ggctgacgga gcagcgcggc tttgacggcc ggacgcaacg ttaccagtat
     5341 gacctgaccg gaaaactcac gcagagtgaa gacgaggggc ttatcaccct ctggcattac
     5401 gatgcgtcag accgtatcac ccggcgcacg gtgaacggtg aaccggcgga gcagtggcag
     5461 tatgacgacc acggctggct gacagaaatc agccacctga gtgaaggcca ccgtgtggcg
     5521 gtccactacg gctatgacga taaaggccgc ctgacgggcg aacggcagac ggtggagaac
     5581 ccggagacgg gggagatgct gtgggagcat gagacggggc atgcgtacag cgaacagggg
     5641 ctggcgaccc gtcaggagcc ggacggtctg cagccggtgg agtggctgac gtatggcagc
     5701 ggttatcttg cggggatgaa gctgggcgga acaccgctgg tcgagtacac gcgggacagg
     5761 ctgcaccgtg agacggcccg cagcttcggc ggggaggcat atgaacttgc caccgcctgg
     5821 aataccagcg gccagctccg gagcaggcac ctgaaccttc cgcagcttga ccgtgactac
     5881 gactggaacg acaacggaca gctaatccgc atcagcggcc cgcaggagag ccgggagtac
     5941 cgttacagcg acacgggaag gctgacgggc gtccacacca cggcggcgaa cctggatatc
     6001 gatatcccgt atgcgacgga cccggcagga aaccggctgc cggacccgga actgcacccg
     6061 gacagcacgc tcacggcatg gccggataac cgcatcgcgg aagatgcgca ctatgtctac
     6121 cgccacgatg aatacggcag gctggcggag aagacggacc gcatcccgga aggggtgata
     6181 cggatgcacg acgagcggac ccaccactac cactacgaca gccagcaccg cctggtgttc
     6241 tacacgcgga tacagcacgg cgaaccacag gtggagagcc ggtacctcta tgacccgctg
     6301 ggccgccgga cgggaaaacg ggtatggcgg cgggagcgtg acctgacggg gtggatgtcg
     6361 ctgtcgcgta aaccggaggt gacatggtac gggtgggacg gtgacaggct gacgacgata
     6421 cagaccggca ccacgcgtat ccagacggta taccagccgg ggagcttcac gccgctcctg
     6481 agaatcgaaa cagagaatgg cgaacaggcg aaggcgcggc accggagcct ggcggaggtg
     6541 ttgcaggagg acacgggtgt gacgctaccg gcggagctgg cggtgatgct gggaaggctg
     6601 gagcgggagc tgcgtgcggg agcggtgagt gcggagagtg aggcatggct tgcgcagtgc
     6661 gggctgacgg cggaacagat ggccgcgcag atggaggatg catacatccc ggagcggagg
     6721 ctgcatcttt accactgtga ccaccgtgga ctgccgcagg cgctcatcac cccggaaggc
     6781 gaaacggcgt ggtgcgggga gtatgacgag tgggggaacc agcttaatga ggagaacccg
     6841 catcacctgt accagccgta ccgtttgccg gggcagcagt atgatgagga gtcgggactg
     6901 tattacaacc gtcaccggta ctacgatccg ttgcaggggc ggtatatcac ccaggatccg
     6961 atagggttga aggggggaat aaatctatac acgtatccac tggtaccaat acgttacact
     7021 gatccactgg ggttagaacg agttataagt gtatatgggc ctcccgctcc agaccgggca
     7081 ggtgctgaaa ctcctcttgt tcttactgat atgactggag gagtgactat ttattatgat
     7141 cctgaaacag gtgattcaat gacttttgat agtagcaata gaattgatcg tcgttctcaa
     7201 cgtggtgctg gtgatccata tacaggtgaa gtcgttggtt gtgagacaaa tgaatcagga
     7261 atatcggcag catatggcac aacgaagatc tatactacag atactagagc aagatggcta
     7321 catggtgggg gatcatcgtt gcgcgatcct tatgctcctc gacaaggctg gaaaccaact
     7381 atgggatgta cccgtgcaca gaatgaagat gtagatgagt tgtgtaagaa agtgacaagt
     7441 tggatgtatt cgcatcctgg agagagaatt agatatgaac gttttaagac acgttaatgc
     7501 gattaacatg ggagtgtgca ttctaatttg ggttattgga tgtgcaaatg ctaaagttct
     7561 taaacgatgt atattacctg ctcctgatgg tggcgtagaa aaactatcaa aacccaactt
     7621 acatggagta attaaaaaag ttgatttgaa cacaaatgaa gcggaaatta aaataaaaga
     7681 ggggggggca gtgagtttta tttttaatga ggaaacattg tattttactg tttttggtgg
     7741 ggattttatt atggatgatt taaaaaaagt aaaaaatacg gaagcatggg tatggtataa
     7801 aaattgcgat agtaaaaata aaaatgtggc agttgaactt cttcaaatct acgaattgca
     7861 tcaatgaaaa atatagttaa atagaggagg ttattaatag caggaaaagc atcacgtgat
     7921 gctgattttt tgcactaaat aattcgcgct aatgttcaat agttaatata tccctcatca
     7981 gggaaagatc accggtgtgc cgtaggcaca aagatgcaaa acgggacgtt ttgcatgtaa
     8041 taagcataag cttgtgaaga gatggtggca ggcccaccgg gatctgctgt cggaagtcgg
     8101 tcccaaacaa ccccggctgc tgtggtaaag agccatggta gtgagcgcag gggcagggaa
     8161 agatcacgta acgctgattt tttgtactaa ataattcgca ttttatgttt aa
//
LOCUS       DAPOAV010000138         8192 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.139, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000138 DAPOAV010000000
VERSION     DAPOAV010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8192
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.139"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            534..752
                     /locus_tag="RN951_004078"
     CDS             534..752
                     /locus_tag="RN951_004078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312842.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HDX2528998.1"
                     /translation="MAMNTVFLHLSEEAIKRLNKLRGWRKVSRSAILREAVEQYLERQ
                     QFPVRKAKGGRQKGEVVGVDDQCKEHKE"
     gene            970..1212
                     /locus_tag="RN951_004079"
     CDS             970..1212
                     /locus_tag="RN951_004079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709694.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2528999.1"
                     /translation="MNSLAGIDMGRILLDLSNEVIKQLGDLEVQRNLPRADLLREAVD
                     QYLINQSQTARTSVPGIWQGCEEDGVEYQRKLREEW"
     gene            complement(1542..2471)
                     /gene="fdhE"
                     /locus_tag="RN951_004080"
     CDS             complement(1542..2471)
                     /gene="fdhE"
                     /locus_tag="RN951_004080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory protein FdhE"
                     /protein_id="HDX2529000.1"
                     /translation="MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLREL
                     AENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEASAQGKPPLDIHVLPRDKH
                     WQKLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFI
                     WAALSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLC
                     ETEWHVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCDTYLKILYQEKDPKIEAV
                     ADDLASLVLDARMEQEGYARSSINPFLFPGEGE"
     gene            complement(2468..3103)
                     /gene="fdoI"
                     /locus_tag="RN951_004081"
     CDS             complement(2468..3103)
                     /gene="fdoI"
                     /locus_tag="RN951_004081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HDX2529001.1"
                     /translation="MKRRDTIVRYTAPERINHWITAFCFILAAVSGLGFLFPSFNWLM
                     QIMGTPQLARILHPFVGVVMFASFIIMFFRYWHHNLINRDDIFWAKNIRKIVVNEEVG
                     DTGRYNFGQKCVFWAAIIFLVLLLVSGVIIWRPYFAPAFSIPVIRFALMLHSFAAVAL
                     IVVIMVHIYAALWVKGTITAMVEGWVTSAWAKKHHPRWYREVRKTTEKKAE"
     gene            complement(3100..4002)
                     /gene="fdoH"
                     /locus_tag="RN951_004082"
     CDS             complement(3100..4002)
                     /gene="fdoH"
                     /locus_tag="RN951_004082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase O subunit beta"
                     /protein_id="HDX2529002.1"
                     /translation="MAYQSQDIIRRSATNGLTPAPQARDFQEEVAKLIDVTTCIGCKA
                     CQVACSEWNDIRDTVGNNIGVYDNPNDLSAKSWTVMRFSEVEQNDKLEWLIRKDGCMH
                     CSDPGCLKACPAEGAIIQYANGIVDFQSEQCIGCGYCIAGCPFDIPRLNPEDNRVYKC
                     TLCVDRVVVGQEPACVKTCPTGAIHFGTKESMKTLASERVAELKTRGYDNAGLYDPAG
                     VGGTHVMYVLHHADKPNLYHGLPENPEISETVKFWKGIWKPLAAVGFAATFAASIFHY
                     VGVGPNRADEEENNLHEEKDEERK"
     gene            complement(4015..7065)
                     /gene="fdnG"
                     /locus_tag="RN951_004083"
     CDS             complement(4015..7065)
                     /gene="fdnG"
                     /locus_tag="RN951_004083"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(6478..6480),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit alpha"
                     /protein_id="HDX2529003.1"
                     /translation="MQVSRRQFFKICAGGMAGTTAAALGFAPSVALAETRQYKLLRTR
                     ETRNTCTYCSVGCGLLMYSLGDGAKNAKASIFHIEGDPDHPVNRGALCPKGAGLVDFI
                     HSESRLKFPEYRAPGSDKWQQISWEEAFDRIAKLMKEDRDANYIAQNAEGVTVNRWLS
                     TGMLCASASSNETGYLTQKFSRALGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWV
                     DIKNANLVVVMGGNAAEAHPVGFRWAMEAKIHNGAKLIVIDPRFTRTAAVADYYAPIR
                     SGTDIAFLSGVLLYLLNNEKFNREYTEAYTNASLIVREDYGFEDGLFTGYDAEKRKYD
                     KSSWTYELDENGFAKRDTTLQHPRCVWNLLKQHVSRYTPDVVENICGTPKDAFLKVCE
                     YIAETSAHDKTASFLYALGWTQHSVGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSN
                     IQGLTDLGLLSQSLPGYMTLPSEKQTDLQTYLTANTPKPLLEGQVNYWGNYPKFFVSM
                     MKAFFGDKATAENSWGFDWLPKWDKGYDVLQYFEMMKEGKVNGYICQGFNPVASFPNK
                     NKVIGCLSKLKFLVTIDPLNTETSNFWQNHGELNEVDSSKIQTEVFRLPSTCFAEENG
                     SIVNSGRWLQWHWKGADAPGIALTDGEILSGIFLRLRKMYSEQGGANPDQVLNMTWNY
                     AIPHEPSSEEVAMESNGKALADITDPATGAVIVKKGQQLSSFAQLRDDGTTSCGCWIF
                     AGSWTPEGNQMARRDNADPSGLGNTLGWAWAWPLNRRILYNRASADPQGNPWDPKRQL
                     LKWDGTKWTGWDIPDYSAAPPGSGVGPFIMQQEGMGRLFALDKMAEGPFPEHYEPFET
                     PLGTNPLHPNVISNPAARIFKDDAEALGKADKFPYVGTTYRLTEHFHYWTKHALLNAI
                     LQPEQFVEIGESLANKLGIAQGDTVKVSSNRGYIKAKAVVTKRIRTLKANGKDIDTIG
                     IPIHWGYEGVAKKGFIANTLTPFVGDANTQTPEFKSFLVNVEKV"
     gene            7259..8092
                     /gene="fdhD"
                     /locus_tag="RN951_004084"
     CDS             7259..8092
                     /gene="fdhD"
                     /locus_tag="RN951_004084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HDX2529004.1"
                     /translation="MKKTQRKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVA
                     LVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSS
                     RRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDF
                     QPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSS
                     RASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLS
                     N"
BASE COUNT         1922 a         2069 c         2147 g         2054 t
ORIGIN      
        1 gcatcattgt cagtatcatt catttactgc tctgtatgtt atgaataatt atgttgtatg
       61 tttgctctta aaccgtggga aggaggctat aatggttgcc aatattaatc tcattaaaca
      121 agaaagttat tctgttgtta atttagaaaa acaactttcc cgaactgtta ccaacaaaat
      181 tataacgatg agcaagtaaa gaccggttgg tggcagtact gaccggtctg tgatgaaaga
      241 ttaatttcac cttaaatcct ggtgctgtta ggatgctgac gtttttcggc tacaccattc
      301 agattatgca aataaatatc tctgaatata atatattcat agcacccata attcatcctg
      361 ggcgataact aaaccatttt tgagtaataa atgaaacaac tgcaacactc ttattatttc
      421 tggaaaacgc ctcgcaaaaa caaaacaaca tgcaaaaatc cgcttttttt aaatgatttt
      481 ccggcgtaat tttcgcacat acattaatga gtaatatatg taaggtattg gtaatggcga
      541 tgaatacggt ttttcttcat ttatcagaag aggcaattaa acggctgaac aagcttcggg
      601 gctggcgtaa ggtttcacga tctgcaattt tacgcgaagc ggtagagcaa tatctggaac
      661 gtcagcaatt cccggtgcgt aaagcaaagg gaggcaggca aaagggggag gtagttggtg
      721 ttgatgatca gtgtaaggag cataaggaat gacaaaaatt tttcattctt gaatataaaa
      781 aacagatgcc cttattctgg tattaataca aggctgtttt acttgaactt ataataactg
      841 caactgttac atcatatctg gaaaacgcct cgcaaaaata aaaaatgatg cgtaaatgag
      901 ctttctttaa agattcggca agggtacttt tctctccata gattcaaaaa tgatattggc
      961 gagatattta tgaactctct ggcaggtata gatatgggca gaattttact cgatttatcg
     1021 aatgaggtga ttaagcaact tggtgatctc gaggtgcagc gtaatcttcc tcgtgcggac
     1081 ctattaaggg aagcggtaga tcaatacctg ataaatcaat cgcaaacagc aagaaccagt
     1141 gttcctggca tctggcaagg gtgtgaggaa gatggtgtcg aatatcagcg taagctgcgc
     1201 gaggaatggt aatgggaaaa aatgatgtca atcagattgc tgacaacgtg cgcgttgttc
     1261 atgccggatg cggcgtgaac gccttatccg gcctacaaag tcgtataaat tcaatgtatt
     1321 gcagtttatt ggtaggcctg ataagcgcag cgcatcaggc aatcttacgc ttgtcatcag
     1381 tctcatgccc ataaccttat tgatgtggtg gtgggtaaat tgaggccaaa ccggcactgg
     1441 cggcatagct tgaggtggta acgcggaata cgagagatgg tgtcgtcaca ccctatgagc
     1501 tgtaatccgg gcgacctgcg ccacccggaa aacgtcagag attactctcc ttcacccgga
     1561 aacaggaacg ggttgatgga actgcgggca tagccttctt gctccattcg tgcgtccagt
     1621 accagagagg cgaggtcatc tgctacggct tcgatttttg gatctttttc ctgatagaga
     1681 attttcaggt aagtgtcgca gtcatcgcag ctttcggctt taatcgcggc ctgttcgtca
     1741 tccagcgacc agtaatgcag tttgccgctc tgctcgcagt tgctgcattt tacgcgcact
     1801 acgtgccatt cagtttcaca caggttgcag tgcaggtaac gtagcccctg agtggtgcca
     1861 atttgcacca tgctggacac cggcatagaa ccacaaaccg ggcaatattg acgttgctcg
     1921 ccgtattcag cgcgggcttt gccggggatc agattggcca tctgcgccca gtagagcgac
     1981 agtgcagccc agataaacgg cgctttatcg ctgctgacgg acgagaaatc agaggcaaac
     2041 agcgcgctgg ccatatcttc cagctcctga gtcgatgcct tctccagatt ctcaatcact
     2101 gccagcgccg ggccgctcat ttcaggtttc agctcagcaa tcagcgccat cagcagcttt
     2161 tgccagtgct tatcacgcgg cagaacgtga atatccagcg ggggcttgcc ttgtgcgctg
     2221 gcttctttaa tgcgcgcagt cagatccatc tccagcggat ggtcgtacag caccacttcc
     2281 tgggcgtggg cgataagcgc agcaaagcgc aggtaatcac ccagaggatt attttctgcc
     2341 agctcgcgca gacgctcggc gcggcggttg tataaattct tgagccgagg gaacaataac
     2401 ggcggaatca tatccgccgt acgtttctcg cttgaaccca gctcatcttg cgggattatg
     2461 cgaatactca ttcagctttc ttttccgttg tcttgcggac ctcacggtac cagcgcgggt
     2521 gatgtttctt cgcccaggcg ctggtaaccc atccttccac catggcggta atcgtgcctt
     2581 tcacccaaag ggcggcgtag atatgcacca tgataaccac aattaacgcc actgcggcaa
     2641 atgaatgcag cattaacgcg aatcggatca ccgggattga gaaagcaggc gcaaaataag
     2701 gacgccagat aatcacgccg ctcaccagca gcagaaccag gaaaataatc gccgcccaga
     2761 aaacgcattt ctgaccgaag ttataacgcc cggtgtcacc tacttcctcg ttgacgacga
     2821 tcttacgaat attcttcgcc caaaagatat catcccgatt gattaggttg tgatgccagt
     2881 aacggaaaaa catgatgatg aacgaggcaa acataaccac gccgacaaac gggtgcagaa
     2941 ttcgcgccag ctgcggtgtg cccatgattt gcatcaacca gttgaaggac gggaacaaaa
     3001 agcccagccc gctcaccgcc gccaggatga agcagaaggc ggtgatccag tggttgatac
     3061 gttccggcgc ggtgtagcgc acgatggtgt cacgtcgttt catttgcgct cctcgtcttt
     3121 ctcttcgtgc agattattct cttcctcatc cgcacggttc ggaccgacac ccacgtagtg
     3181 gaagatactg gccgcaaagg tagccgcaaa gccaacagcc gcgagcggtt tccagatgcc
     3241 tttccagaat ttcacggttt cgctgatttc cgggttctcc ggcaagccat gatacagatt
     3301 tggcttgtca gcatggtgca gcacgtacat gacgtgtgta ccaccgacgc ctgccggatc
     3361 gtacagaccc gcattgtcgt aaccgcgggt tttcagctca gcaacgcgct cgctcgccag
     3421 cgttttcatc gactctttcg taccgaagtg aatcgcgccc gttgggcagg tcttcacgca
     3481 ggctggttct tgcccaacca ccacgcggtc aacgcacagc gtacatttgt agacgcggtt
     3541 gtcttccggg ttgaggcgcg gaatgtcgaa cggacagccc gcaatgcaat aaccgcagcc
     3601 aatgcactgc tcggactgga agtcgacgat accgttggca tactgaataa ttgcaccttc
     3661 cgccgggcac gctttcaggc agcctggatc ggaacagtgc atacagccgt ctttgcggat
     3721 cagccattcc agtttgtcgt tctgctccac ttccgagaag cgcattaccg tccacgattt
     3781 ggcgcttaaa tcattggggt tgtcgtacac cccaatgtta ttgccgacgg tatcgcgaat
     3841 gtcgttccac tctgaacacg ccacctgaca ggctttacag ccgatacagg tggtaacgtc
     3901 gatgagtttc gccacttctt cctggaagtc ccgcgcctga ggcgcggggg tcagaccgtt
     3961 agtcgcggaa cgacgaatga tatcttgaga ttgataagcc atatgtcgtc tccgttacac
     4021 cttttccaca ttcacaagga aggacttaaa ctccggcgtc tgcgtgttcg catcaccaac
     4081 gaatggcgtt aaagtattgg caataaagcc ttttttagct acgccttcat agccccagtg
     4141 aatcggaata ccgatggtat cgatatcttt gccgttcgct ttcagcgtgc gaatacgttt
     4201 ggtcaccacc gctttggctt tgatatagcc acggttggag gagactttca cggtatcgcc
     4261 ctgggcaatg ccaagtttat tcgccagcga ctccccgatt tccacaaact gctctggctg
     4321 caaaatcgcg ttcaacagcg cgtgtttggt ccagtagtgg aagtgctcgg tcagacgata
     4381 ggtggttccg acatacggga acttatcggc tttacccaat gcttcggcgt cgtctttaaa
     4441 gatacgtgca gccgggttcg agataacgtt tggatgcagc gggttagttc ccagcggcgt
     4501 ttcaaacggc tcgtagtgtt ccgggaacgg accttccgcc atcttatcga gggcaaacag
     4561 acgccccatg ccttcctgct gcatgataaa cggcccgacg ccgctacccg gaggcgctgc
     4621 gctgtagtcc ggaatatccc agccggtcca cttagtgccg tcccatttca gcaactgacg
     4681 cttcggatcc cacgggttac cctgcggatc tgcggaggcg cggttataca gaatgcggcg
     4741 gttaagcggc catgcccatg cccagcccag cgtgttaccg aggccagacg gatcggcgtt
     4801 atcacggcgt gccatctggt tgccttccgg cgtccagcta ccggcgaaaa tccagcagcc
     4861 acaggaggtt gtaccgtcat cgcgcaattg ggcgaacgaa ctaagttgtt ggcctttctt
     4921 gacgataacc gcaccggttg ccggatcggt aatatcggcc agcgccttac cgttgctctc
     4981 catcgccact tcttctgaag atggctcatg cggaatggcg tagttccatg tcatgttcag
     5041 cacctggtcc gggttcgcgc caccctgttc ggaatacatc ttgcgcaagc gcaggaagat
     5101 accggagagg atctcgccgt cagtcagcgc aatccccggg gcgtccgcac ctttccagtg
     5161 ccactgtaac cagcgacctg agttaacgat agaaccgttc tcttccgcga agcaggtcga
     5221 tggcagacgg aacacttcgg tctggatctt cgacgagtca acttcgttca gctcaccgtg
     5281 gttctgccag aagttagagg tttcagtgtt cagtgggtcg atggtgacga ggaacttcag
     5341 tttcgacaga caaccgatca ctttgttttt gttcgggaat gaggcaacag ggttaaagcc
     5401 ctggcagata tagccattga ccttgccctc tttcatcatc tcgaagtatt gcaggacgtc
     5461 gtagccttta tcccacttcg gcaaccagtc aaagccccag ctattttccg ccgtcgcttt
     5521 atcaccaaag aaggccttca tcatagagac gaagaatttc gggtagttgc cccagtagtt
     5581 tacctggcct tccagcagcg gttttggcgt gttggcggta aggtaggttt gcagatcggt
     5641 ctgcttctcg cttggcagcg tcatgtaacc tggcaggctc tgcgacagca gccccaggtc
     5701 cgtcagcccc tgaatattgg agtgaccgcg cagggcgtta acgccgccgc ctgccatccc
     5761 catattgccg agcagcagct ggatcatcgc catcgtacga atgttttgcg caccaacgga
     5821 gtgttgcgtc cagccgaggg catacaggaa cgaggcagtt ttatcgtgag cactggtttc
     5881 tgcgatgtat tcgcagactt tcaggaacgc gtcttttggc gtaccacaga tgttttcaac
     5941 cacatctggc gtgtagcggg aaacgtgctg tttcagcaag ttccacacgc agcgcggatg
     6001 ttgcagcgtg gtatcgcgtt tggcgaagcc gttttcgtcc agttcataag tccaggagga
     6061 tttatcgtac ttgcgttttt ccgcgtcgta gccggtgaac aggccatctt caaagccgta
     6121 atcctcacgc acgatcaggc tggcgttggt ataggcttcg gtgtattcgc ggttgaattt
     6181 ttcattgttc agcaggtaca gcaatacgcc tgacaggaaa gcaatgtcag taccggaacg
     6241 aataggggca tagtagtcag ctaccgccgc cgtacgcgta aagcgaggat cgatcacaat
     6301 cagcttcgcg ccgttgtgaa ttttggcttc catcgcccag cggaacccga ccgggtgagc
     6361 ttcagcggcg ttaccgccca tcaccacgac gaggttggcg ttcttgatgt cgacccagtg
     6421 gttggtcatc gcaccgcgac caaatgttgg agcaagactt gctaccgttg gtccgtgtca
     6481 gacacgcgcc tggttgtcga ccgcgagcat acccagcgcg cgggagaatt tttgcgttaa
     6541 atagccggtt tcgttactcg acgcggaagc acacagcatc ccggtggaga gccagcggtt
     6601 aacagtcacg ccttcggcgt tttgcgcaat gtagttagca tcgcggtctt ctttcatcag
     6661 tttggcgatg cgatcaaacg cctcttccca actgatttgc tgccatttat cagaacctgg
     6721 cgcacggtat tccggaaact tcagacggct ttcggagtgg atgaaatcca ccaggccagc
     6781 gcctttcgga caaagtgcac cgcggttgac cgggtgatcc ggatcgcctt cgatatggaa
     6841 gatagatgct ttggcgtttt ttgctccgtc accgaggctg tacatcaaca gcccacagcc
     6901 tacggaacaa taggtgcagg tattacgggt ttcgcgggtg cgcagcagtt tatactgccg
     6961 ggtttccgcg agtgctacgc tgggtgcaaa acccagtgcc gctgccgtgg tgcctgccat
     7021 accgccagcg cagatcttaa agaactgcct tctgctgacc tgcatggatt gctccttgtt
     7081 tcgacattgt cacgtcccat ttacattcgc ttgctgcgtg tgcagggagt gggagttatt
     7141 tttctttgcg gaaggggccg caaaggtcca gaattggctc aatttccctc catccaggaa
     7201 gggtttgtaa cagaatacca taatgttggt gtgtgtgttc ttatctggtt aagagaaagt
     7261 gaaaaaaaca cagcgaaaag aaatcgaaaa tgtgacaaat atcacaggtg ttcgtcaaat
     7321 tgagttatgg cggcgtgatg atttacaaca cccacggtta gatgaggtcg cggaagaagt
     7381 tcccgttgcg ctggtctaca acggcatttc gcatgtggtg atgatggcgt cgcccaaaga
     7441 ccttgagtac tttgcgctcg gtttttcgct ttccgagggg attatcgaaa gtccgcgcga
     7501 tatcttcggc atggatgtcg ttccttcctg taatggtctt gaagtacaaa ttgagctttc
     7561 cagccgccgc tttatggggt tgaaggagcg ccgccgggcg ctggcgggac gtacgggctg
     7621 tggcgtatgc ggcgtggagc aacttaatga catcggaaaa ccggtgcagc cgctaccgtt
     7681 cacccagacg tttgatctca acaaactgga tgatgcatta cgtcatctca acgattttca
     7741 gccagtgggg caactgactg gttgtactca cgccgctgcc tggatgttgc catctggcga
     7801 actggtcggc gggcatgaag acgtgggtcg ccatgtggcg ctggacaaac tgttaggccg
     7861 ccggtcacaa gaaggggaaa gctggcagca aggtgcggta ctggtttcca gtcgtgccag
     7921 ttatgaaatg gtgcaaaagt cggcgatgtg cggcgtagag attttgtttg cggtgtctgc
     7981 cgcgaccacg cttgctgtag aagtggctga gcgctgtaat ctgacactgg taggtttttg
     8041 taaaccgggt cgggcaacgg tttataccca tccgcagcgt ttgagcaatt aattaaaata
     8101 agtcctgcga aatatattaa attgcaggac ttattcattt cgtgaatttt attattttat
     8161 ttataaacaa aatgcgtgta gtggcgtttt ct
//
LOCUS       DAPOAV010000139         8106 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.140, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000139 DAPOAV010000000
VERSION     DAPOAV010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8106
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.140"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(68..154)
                     /locus_tag="RN951_004085"
     tRNA            complement(68..154)
                     /locus_tag="RN951_004085"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(118..120),aa:Leu,seq:cag)
     gene            complement(455..1486)
                     /gene="rsmC"
                     /locus_tag="RN951_004086"
     CDS             complement(455..1486)
                     /gene="rsmC"
                     /locus_tag="RN951_004086"
                     /EC_number="2.1.1.172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1207)-N(2))-methyltransferase
                     RsmC"
                     /protein_id="HDX2529005.1"
                     /translation="MSAFTPASEVLLRHSDDFEQNRILFAGDLQDDLPARLDTAASRA
                     HTQQFHHWQVLSRQMGDNARFSLVATADDVADCDTLIYYWPKNKPEAQFQLMNLLSLL
                     PVGTDIFVVGENRSGVRSAEQMLADYAPLNKVDSARRCGLYFGRLEKQPVFDADKFWG
                     EYSVDGLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGSGAGVLSVAFARHS
                     PKIRLTLCDVSAPAVEASRATLAANGVEGEVFASNVFSEVKGRFDMIISNPPFHDGMQ
                     TSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPDVLDETFGFHEVIAQTGRFKVYRA
                     IMTRQAKKG"
     gene            1589..2002
                     /gene="holD"
                     /locus_tag="RN951_004087"
     CDS             1589..2002
                     /gene="holD"
                     /locus_tag="RN951_004087"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit psi"
                     /protein_id="HDX2529006.1"
                     /translation="MTSRRDWQLQQLGITQWSLRRPGALQGEIAIAIPAHVRLVMVAN
                     DLPALTDPLVSDVLRALTVSPDQVLQLTPEKIAMLPQGSRCNSWRLGTDEPLSLEGAQ
                     VASPALTELRANPTARAALWQQICTYEHDFFPRND"
     gene            1971..2417
                     /gene="rimI"
                     /locus_tag="RN951_004088"
     CDS             1971..2417
                     /gene="rimI"
                     /locus_tag="RN951_004088"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDX2529007.1"
                     /translation="MNTISSLETTDLPAAFHIEQRAHAFPWSEKTFASNQGERYLNFQ
                     LTQNGKMAAFAITQVVLDEATLFNIAVDPDYQRQGLGRALLEHLIDELEKRGVATLWL
                     EVRASNAAAIALYESLGFNEATIRRNYYPTTDGREDAIIMALPISM"
     gene            2432..3109
                     /gene="yjjG"
                     /locus_tag="RN951_004089"
     CDS             2432..3109
                     /gene="yjjG"
                     /locus_tag="RN951_004089"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine 5'-nucleotidase"
                     /protein_id="HDX2529008.1"
                     /translation="MKWDWIFFDADETLFTFDSFTGLQRMFLDYSVTFTAEDFQDYQA
                     VNKPLWVDYQNGAITSLQLQHGRFESWAERLNVEPGKLNEAFINAMAEICTPLPGAVS
                     LLNAIRGNAKIGIITNGFSALQQVRLERTGLRDYFDLLVISEEVGVAKPNKKIFDYAL
                     EQAGNPDRSRVLMVGDTAESDILGGINAGLATCWLNAHNREQPEGIAPTWTVSSLHEL
                     EQLLCKH"
     gene            3200..4789
                     /gene="prfC"
                     /locus_tag="RN951_004090"
     CDS             3200..4789
                     /gene="prfC"
                     /locus_tag="RN951_004090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HDX2529009.1"
                     /translation="MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAG
                     TVKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRT
                     LTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVEN
                     ELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQSGKGHTIQEVRIVKGLNNPDLDAA
                     VGEDLAQQLRDELELVKGASNEFDKELFLAGEITPVFFGTALGNFGVDHMLDGLVEWA
                     PAPMPRQTDTRTVEASEDKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQV
                     RTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPN
                     FAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVV
                     SRLKSEYNVEAVYESVNVATARWVECADAKKFEEFKRKNESQLALDGGDNLAYIATSM
                     VNLRLAQERYPDVQFHQTREH"
     gene            5182..5787
                     /gene="osmY"
                     /locus_tag="RN951_004091"
     CDS             5182..5787
                     /gene="osmY"
                     /locus_tag="RN951_004091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710115.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone OsmY"
                     /protein_id="HDX2529010.1"
                     /translation="MTMTRLKISKTLLAVMLTSAVATGSAYAENNAQTTNESAGQKVD
                     SSMNKVGNFMDDSAITAKVKAALVDHDNIKSTDISVKTDQKVVTLSGFVESQAQAEEA
                     VKVAKGVEGVTSVSDKLHVRDAKEGSVKGYAGDTATTSEIKAKLLADDIVPSRKVKVE
                     TTDGVVQLSGTVDSQAQSDRAESIAKAVDGVKSVKNDLKTK"
     gene            5914..6075
                     /locus_tag="RN951_004092"
     CDS             5914..6075
                     /locus_tag="RN951_004092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1328 domain-containing protein"
                     /protein_id="HDX2529011.1"
                     /translation="MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIILFLV
                     SLFMGRKRP"
     gene            6197..7270
                     /locus_tag="RN951_004093"
     CDS             6197..7270
                     /locus_tag="RN951_004093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin family protein"
                     /protein_id="HDX2529012.1"
                     /translation="MGQRIPVTLGNIAPLSLRPFQPGRIALVCEGGGQRGIFTAGVLD
                     EFMRAQFNPFDLYLGTSAGAQNLSAFICNQPGYARKVIMRYTTKREFFDPLRFVRGGN
                     LIDLDWLVEATASQMPLQMDTAARLFDSGKSFYMCACRQDDYAPNYFLPTKQNWLDVI
                     RASSAIPGFYRSGVSLEGINYLDGGISDAIPVKEAARQGAKTLVVIRTVPSQMYYTPQ
                     WFKRMERWLGDSSLQPLVNLVQHHETSYRDIQQFIEKPPGKLRIFEIYPPKPLHSIAL
                     GSRIPALREDYKLGRLCGRYFLATVGKLLTEKAPLTRHLVPVVTPESIVIPPAPVAND
                     TLVAEVIDAPQANDPTFNNEDLA"
     gene            7267..8049
                     /locus_tag="RN951_004094"
     CDS             7267..8049
                     /locus_tag="RN951_004094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313363.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDX2529013.1"
                     /translation="MICRFIDTHCHFDFPPFSGDEEASLQRAAQAGVGKIIVPATEAE
                     NFARVQALAEKYQPLYAALGLHPGMLEKHSDVSLDQLQQALERRPAKVVAVGEIGLDL
                     FGDDPQFERQQWLLDEQLKLAKRYDLPVILHSRRTHDKLAMHLKRHDLSRTGVVHGFS
                     GSLQQAERFVQLGYKIGVGGTITYPRASKTRDVIAKLPLASLLLETDAPDMPLNGFQG
                     QPNRPEQAARVFDVLCELRPEPEDEIAEVLLNNTYAVFSVRG"
BASE COUNT         1935 a         2092 c         2205 g         1874 t
ORIGIN      
        1 acctgaagct agcgcgtcta ccaattccgc caccttcgcc cagtgcgagc aatatcaacg
       61 tggtttttgg tgcgaggggg gggacttgaa cccccacgtc cgtaaggaca ctaacacctg
      121 aagctagcgc gtctaccaat tccgccacct tcgcatacca tcaattctta aaaagaattg
      181 ctaccacgga ggcgcattct agtggttttc agcttttcgt caatagttaa ttatcgccgg
      241 aggtgtaatt gctggaaaaa tgtccatcag gaaactaacg tgcaggtttt gtaggtcgga
      301 taaggcgttc acgccgcatc cgacacggta tttgggtgca gatgccagat gcgacgcggg
      361 cgcgtcttat ctggcctacg aagggctaac gtgcaggttt tgtaggttgt ataaggcgag
      421 cacgccgcat ccgacaaggc ttgcggcggg atacttaacc tttcttcgcc tggcgggtca
      481 taatggcgcg atacaccttg aagcgcccgg tttgcgcgat cacttcatgg aagccaaatg
      541 tctcatccag cacgtccgga taaggcagga aggcgttcgc tacaattcgc agctcgccgc
      601 cgctgttaag gtgacgcacc gcgccgcgaa tcagcgtttg cgccgcatcg aggctggttt
      661 gcatcccatc gtggaacggc gggttggaga tgatcatatc aaaacgacct ttcacctcgg
      721 aaaagacgtt actggcaaag acttcacctt caacaccgtt ggccgcaagt gttgcgcggc
      781 tggcttctac cgctggcgca gagacatcgc acagagtgag acgaattttc ggtgaatggc
      841 gcgcaaaggc aaccgaaagc acgcccgcgc cgctgccgac atccagcact ttacctttcg
      901 tgtgcggagt taacgtcgag agcagcaact ggctaccgac atccagaccg tcgcggctaa
      961 acacgccagg cagcgttttg accgtcaggc catcgacgct gtattcgccc cagaatttat
     1021 cggcatcaaa taccggctgt ttttccagac gaccaaaata gaggccacag cgacgggcgc
     1081 tgtcgacttt attcaacggc gcataatctg ccagcatctg ttcggcgctg cgcacgccgc
     1141 tgcggttctc gccaacgaca aaaatatccg tccccaccgg cagcagagaa agtaaattca
     1201 tcaactggaa ctgggcttcc ggtttgttct tcggccagta gtaaatcaaa gtatcgcaat
     1261 ctgcgacgtc atccgccgtg gcgaccagac taaaacgggc gttatcaccc atctggcggc
     1321 ttaacacctg ccagtggtgg aattgctggg tatgagcacg gctggccgcg gtatctaaac
     1381 gcgcgggcag gtcatcctgt aagtctccgg caaaaagaat acggttttgt tcgaaatcat
     1441 cactgtgacg cagcaagact tcacttgccg gggtaaatgc agacatggaa tgctcctcaa
     1501 ttgatactgg cggcgattat agccatatgt tggcgcggta tcgacgaatt tgctatattt
     1561 gcgcccctga caacaggagc gattcgctat gacatcccga cgagactggc agttacagca
     1621 actgggcatt acccagtggt cgctgcgtcg ccctggcgcg ttgcaggggg agattgccat
     1681 tgcgatcccg gcacacgtcc gtctggtgat ggtggcaaac gatcttcccg ccctgactga
     1741 tcctttagtg agcgatgttc tgcgcgcatt aaccgtcagc cccgatcaag tgctgcaact
     1801 gacgccagaa aaaatcgcga tgctgccgca aggcagtcgc tgcaacagct ggcggttggg
     1861 tactgacgaa ccgctatcac tggaaggcgc tcaggtggca tcaccggcgc tcaccgaatt
     1921 acgggcaaac ccaacggcac gcgccgcgtt atggcaacaa atttgcacat atgaacacga
     1981 tttcttccct cgaaacgact gatttaccag cggctttcca cattgaacaa cgcgcccacg
     2041 cctttccgtg gagtgaaaaa acctttgcca gcaaccaggg cgagcgttat ctcaactttc
     2101 agttaacgca aaacggcaaa atggcggcgt ttgcgattac gcaagtggtg ctggatgaag
     2161 ctacattgtt caatattgcg gtcgatcccg actatcagcg tcagggactg ggaagggcgc
     2221 tgctggaaca tctgatcgac gaactggaaa aacgcggcgt ggcgacgcta tggctggaag
     2281 tccgtgcctc aaacgctgcc gccattgcac tgtacgaaag tttaggcttt aacgaggcga
     2341 cgattcgccg caattactac cccaccacgg acggtcgcga agacgccatc atcatggcgt
     2401 tgccaatcag tatgtaagac aaggtggaat aatgaagtgg gactggattt tctttgatgc
     2461 cgatgaaacg ctgtttacct ttgactcatt caccggcctg cagcggatgt ttcttgatta
     2521 cagcgtcacc tttaccgctg aagattttca ggactatcag gccgttaaca agccactgtg
     2581 ggtggattat caaaacggcg cgatcacttc attacagctt cagcacgggc ggtttgagag
     2641 ctgggccgaa cggctgaacg tcgagccggg taaactcaac gaagccttta ttaatgcgat
     2701 ggcggaaatc tgtacgccgc tgccgggagc ggtttctctg cttaacgcca ttcgtggcaa
     2761 cgccaaaatc ggcatcatca ccaacggttt tagcgccttg caacaggtgc gtctggaacg
     2821 cacgggcctg cgtgattact tcgatttgct ggtgatttcc gaagaagttg gcgttgctaa
     2881 accgaataag aaaattttcg attatgcgct ggaacaggcg ggcaatcctg accgttcacg
     2941 cgtgctgatg gttggcgaca ctgccgagtc cgatattctc ggtggcatca acgccgggct
     3001 tgcgacctgc tggctgaatg cgcacaatcg cgagcaacca gaaggcatcg cgcccacctg
     3061 gaccgtttct tcgttgcacg aactggagca gctcctgtgt aaacactgat tgcctccccc
     3121 ccgttgatgg gtaaaatagc cgcaattttt cgttttcaac aagcgcggcg cgatgccgct
     3181 tactcaagaa gaaagaatta tgacgttgtc tccttatttg caagaggtgg cgaagcgccg
     3241 cacttttgcc attatttctc acccggacgc cggtaaaact accatcaccg agaaggtgct
     3301 gctgttcgga caggccattc agaccgccgg tacagtaaaa ggccgtggct ctaaccagca
     3361 cgctaagtcg gactggatgg agatggaaaa gcagcgtggg atctccatta ccacgtctgt
     3421 gatgcagttt ccgtatcacg actgcctggt taacctgctc gacaccccgg ggcacgaaga
     3481 cttctcggaa gatacctatc gtaccctgac ggcggtggac tgctgcctga tggttatcga
     3541 cgctgcaaaa ggtgttgaag atcgtacccg caagctgatg gaagttaccc gtctgcgcga
     3601 cacgccgatc ctcaccttta tgaacaaact tgaccgtgat atccgcgacc cgatggagct
     3661 gctcgatgaa gttgagaacg agctgaaaat cggctgtgca ccgatcacct ggccgattgg
     3721 ctgcggcaag ctgtttaaag gcgtttacca cctttataaa gatgaaacct atctctatca
     3781 gagcggtaaa ggccacacca ttcaggaagt ccgcattgtt aaagggctga ataacccgga
     3841 tctcgacgct gcggttggtg aagatctggc gcagcagctg cgtgatgaac tggagctggt
     3901 gaaaggcgcg tctaacgagt tcgacaaaga attgttcctt gcgggcgaaa tcactccggt
     3961 attcttcggt actgcgctgg gtaacttcgg cgttgatcat atgctggatg gcctggtgga
     4021 gtgggcacct gcgccgatgc cgcgtcagac tgatacccgt actgtagaag cgagcgaaga
     4081 caaatttacc ggcttcgtat ttaaaattca ggccaacatg gacccgaaac accgtgaccg
     4141 cgtggcgttt atgcgcgtgg tatccggtaa atatgaaaaa ggcatgaagc tgcgccaggt
     4201 gcgcactgcg aaagatgtgg tgatctccga cgcgctgacc tttatggcgg gcgaccgttc
     4261 gcacgttgaa gaagcgtatc cgggcgatat cctcggcctg cataaccacg gcactattca
     4321 gatcggcgac acctttaccc agggtgagat gatgaagttc actggtattc cgaacttcgc
     4381 gccggaactg ttccgtcgta tccgcctgaa agatccgctg aagcaaaaac agctgctcaa
     4441 agggctggta cagctttccg aagagggcgc ggtgcaggtg ttccgtccga tctccaacaa
     4501 cgacctgatc gttggtgcag ttggtgtgct gcagtttgat gtggtggtat cgcgcctgaa
     4561 gagcgaatac aacgttgaag cagtgtatga gtcagtcaac gttgccactg cccgctgggt
     4621 agaatgtgcg gacgcgaaga aattcgaaga gttcaagcgt aagaacgaaa gccaactggc
     4681 gcttgatggc ggcgataacc tcgcttacat cgctaccagc atggtaaacc tgcgcctggc
     4741 gcaggaacgt tatccggacg ttcagttcca ccagacccgc gagcattaat tcttgcctcc
     4801 agggcgcggt agccgctgcg ccctgtcaat ttcccttcct tattagccgc ttacggaatg
     4861 ttcttaaaac attcactttt gcttatgttt tagctgatat cccgagcggt ttcaaaattg
     4921 tgatctatat ttaacaaagt aatgacattt ctgacggcgt taaataccgt tcaatgcgta
     4981 gatatcagta tctaaagccg tcgattgtca ttctaccgat attaataact gattcagagg
     5041 ctgtaatggt cgttattcat cacccatcgc ttttgtgatg gcggccattg acttctgtag
     5101 agggtgaagt ctctccctat tcagcaatgc aacctcgtgt tgccaggctc aaattatgag
     5161 caaacataca ggaataaatc gatgactatg acaagactga agatttcgaa aactctgctg
     5221 gctgtaatgt tgacctctgc cgtcgcgacc ggctctgcct acgcggaaaa caacgcgcag
     5281 actaccaatg aaagcgcagg gcaaaaagtc gatagctcta tgaataaagt cggtaatttc
     5341 atggatgaca gcgccatcac cgcgaaagtg aaggcggccc tggtggatca tgacaacatc
     5401 aagagcaccg atatctctgt caaaaccgat caaaaagtcg tgaccctgag cggtttcgtt
     5461 gaaagccagg ctcaggccga agaggcagtg aaagtggcca aaggcgttga aggcgtgacc
     5521 tctgtcagcg acaaactgca cgttcgcgac gctaaagaag gctctgtgaa gggctacgcg
     5581 ggtgacaccg ccaccaccag tgaaatcaaa gccaaactgc tggcggacga tatcgttcct
     5641 tcacgtaaag tgaaagttga aaccaccgat ggtgtggttc agctctccgg taccgtagat
     5701 tctcaggcac aaagtgaccg tgctgaaagt atcgccaaag cggtagatgg tgtgaaaagc
     5761 gttaaaaatg atctgaaaac taagtaattc gtcgtaattc gtcctcccga actttgtcgg
     5821 gaggcgcgat gtgcaccaca ctaaaaatat cgcattgagt gattttcacg ctcatatcaa
     5881 gcggtgacat taactatggt aaaggagacg cttatgtttc gttggggcat catatttctg
     5941 gttatcgcgt taatcgccgc cgcacttggg tttggtggtc tggccggtac cgctgcaggc
     6001 gcagctaaaa ttgtctttgt cgtcgggatt attctgttcc tggtgagttt gttcatgggc
     6061 cgaaaacgac cctagatttc agaccattaa gaaaatttta tccaaagcca gtccagcgga
     6121 ctggcttttg cggttttagc gaataataaa ttgcgttact ttgtcattct ttcacaacaa
     6181 aaacaggaag gcagaggtgg ggcagcgaat acctgtaacg cttggtaata ttgcgccgtt
     6241 gtcgctaagg ccgttccagc ctggacgaat agctctggtg tgcgaaggcg gcggacagcg
     6301 tggaattttc acggctggcg tgctggatga gtttatgcgc gcgcagttta atcctttcga
     6361 tctttatctc ggcacatctg ccggggcgca gaacctctcg gcgtttatct gcaatcagcc
     6421 cggttacgcg cgcaaagtca tcatgcgcta taccacaaaa cgcgaatttt tcgatccatt
     6481 gcgctttgtc cgtggaggaa atcttatcga tctcgactgg ctggtggagg ccactgcaag
     6541 ccagatgccg ttgcaaatgg ataccgccgc gcggttgttt gacagcggca aatcgtttta
     6601 tatgtgcgcc tgtcgtcagg atgactacgc gccgaattac tttttaccaa ccaaacaaaa
     6661 ctggctggat gtgattcgcg cctccagtgc gatacctggc ttttatcgta gcggagtgtc
     6721 gctggaaggc attaactacc tggatggcgg gatcagtgat gcgattccgg ttaaagaggc
     6781 ggcaaggcag ggcgctaaaa cgttggtcgt cattcgcact gtgccgtcac aaatgtacta
     6841 cacgccgcag tggttcaaac gcatggaacg ctggctgggt gacagtagcc tgcagccgct
     6901 ggtcaatctg gtgcagcatc atgaaaccag ctatcgtgac attcagcaat ttattgagaa
     6961 accaccgggc aagctgcgga tattcgaaat ttatccaccg aagccattac atagtatcgc
     7021 gcttggcagt cggattccgg cgctgcgtga agactataaa cttgggcgtt tatgcggtcg
     7081 ttatttcctc gccacggttg gcaagctatt aactgaaaaa gcgccgctta cccgccatct
     7141 ggtgccagtg gtgacgccgg aatcgattgt cattccgcct gcgccagtcg ccaacgatac
     7201 gctggttgcc gaagtgattg acgctccgca ggcgaacgac ccgacattta acaatgagga
     7261 tctggcttga tttgccgttt tatcgacacc cactgccatt ttgatttccc gccgtttagt
     7321 ggcgatgaag aggccagcct gcaacgcgcg gcacaagcgg gcgtaggcaa gatcattgtt
     7381 ccggcgacag aggcggaaaa ttttgcccgt gtgcaggcgt tagcggaaaa atatcaaccg
     7441 ctgtatgccg cattgggctt gcatcctggt atgttggaaa aacatagcga tgtgtctctt
     7501 gatcagctac agcaggcgct ggaaaggcgt ccggcgaagg tggtggcggt gggggagatc
     7561 ggtctggatc tcttcggcga cgatccgcaa tttgagaggc agcagtggtt actcgacgaa
     7621 caactgaaac tggcgaaacg ctacgatctg ccggtgatcc tgcattcacg gcgcacacac
     7681 gacaaattgg cgatgcatct taaacgccac gatttatcgc gcactggcgt ggttcacggt
     7741 ttttccggca gcctgcaaca ggccgagcgg tttgtacagt tgggctacaa aatcggcgta
     7801 ggcggtacta tcacctatcc acgcgccagt aaaacccgcg atgtcatcgc aaaattaccg
     7861 ctggcatcgt tgttgctgga aaccgacgcg ccggatatgc cgctcaacgg ctttcagggg
     7921 cagcctaacc gcccggaaca ggctgcacgg gtgtttgacg tgctttgcga gttgcgcccg
     7981 gaaccagaag atgagattgc cgaagtgttg cttaataata cgtatgcggt gtttagcgtt
     8041 cgtgggtagt ttacccttcg taggcagcat ccggcagtcg gcgcataatg cctgatgcga
     8101 cgcttg
//
LOCUS       DAPOAV010000140         7994 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.141, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000140 DAPOAV010000000
VERSION     DAPOAV010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7994
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.141"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(689..961)
                     /locus_tag="RN951_004095"
     CDS             complement(689..961)
                     /locus_tag="RN951_004095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ogr/Delta-like zinc finger family protein"
                     /protein_id="HDX2529014.1"
                     /translation="MALKCPECGTVAHARTAAYEAPSVKRSWYQCQNLECSCTFTALE
                     SVDKIIMKPRRNEQEPDKSQTPVKQQQTLNRYGSASKLSSRQQIPV"
     gene            complement(967..1518)
                     /locus_tag="RN951_004096"
     CDS             complement(967..1518)
                     /locus_tag="RN951_004096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage polarity suppression protein"
                     /protein_id="HDX2529015.1"
                     /translation="MTARGTPDQALTSFRNARILWAGHSESRKAVEQQIASLLTATEK
                     PADYARQLELLRERLDVLKWQINCAARECIYSQHLLMEACTEAALSNFMQANGAALTS
                     ALAPFLKGRGGVDVAFRILRSALVRQLAITPPEIVGDYREILDESGLMPDPGMIRDCQ
                     GSYTPAQHLRFQQRLNDINDIQE"
     gene            complement(1515..2258)
                     /locus_tag="RN951_004097"
     CDS             complement(1515..2258)
                     /locus_tag="RN951_004097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation initiation protein"
                     /protein_id="HDX2529016.1"
                     /translation="MNNTAVNNNLSTFPAVTQRALETMNTARNAWLEARRQQKAAADN
                     IATIRQRRAEMEATTNTLNEEWRTLFRESQGVVSKEMKKLRTEIALGRETLEDFDELL
                     AAQESENALLPQKAAELAGKYIHAHNILVDIRAKQIWEDFMQSHGKALIQTLSLLKST
                     MGREASAVVGVVNSVNDPDTVLKDFIHKHITRPALANDAMPEQDPVFKLAGVAPDYAA
                     RLDFSNQLSPAAMHKIKVRQELAEKEKAV"
     gene            complement(2659..5331)
                     /locus_tag="RN951_004098"
     CDS             complement(2659..5331)
                     /locus_tag="RN951_004098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000211874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HDX2529017.1"
                     /translation="MTIQTVTQISAAARGKWPVILQMLRIDVPENGRHGPCPKCGGKD
                     RFRLDDLDGRGTWICSQCGNGDGLDLVKLVTGYSVRKAAQEVAQMLNVPDVQELPVKP
                     ARQKAPKRDMGLTVAALMKESHTGESAYLTGKGFAGYPASLTGSVQHISGKDFPAGSL
                     LLPLTTNTGAVTGAQLIAPTGEKSILPGSTMKGAFVSLSPLPSEPPVQVVITEGYATA
                     LTVSQLTAGCVVAAISAGNLPNVAQSLRARWPEVKIIIAGDNDFQDGGENPGRAFAER
                     AAKSVGGWMTLPPGEIKADWNDFHREHGITRAREAFRNGLVLCGEGRTQLPHGFRLTQ
                     EYLWYEKQVQRNGETEIQNVKICSPLRVTAITCDADGGNFGRLLEWEDTWGECRRWAM
                     PMEMLSGSGEELRRVLLVNGLSYISTTGEARARLMEYISLCKPERRVTCVSRTGWHGQ
                     VYVLQDEVSGEGAEGVILQTTSVQGRDFRVSGTTEEWREHVSRYCTGNSRVAFAVSLA
                     FAAPLLRLVGMDGGGYHLKGESTDGKTTTMKAATSVCGGPDYWQTWRATGNALEGCAS
                     RRNDAAMMLDEIREVDGREAGNIAYMLANGQGKGRAGTDGELRTRKQWRLLFFSTGEL
                     SLTEHAAKAGERTFAGMEVRMIQIPSDSGKFGVFEELHGFDSGKALAEHLEWATSCYY
                     GSPFREWLKALTADLNGLTAQAKSLMKEYAAALTPKDAGNQVGRAVNRFALVAMAGEL
                     ATRLGITGWPEGEALRATRVCLNAWLKDRGHTANQEDIAALEQVRSFFTANQYSRFAD
                     WYDERNRPGNMVGWRRVEKGSTAQGTEAVTTFYVMPSGWKEICRGFDPRKVARLCADR
                     GYLLPSTDGKLQTTIRPPEMNPRRLYVFNSEVPG"
     gene            complement(5328..5711)
                     /locus_tag="RN951_004099"
     CDS             complement(5328..5711)
                     /locus_tag="RN951_004099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5375 family protein"
                     /protein_id="HDX2529018.1"
                     /translation="MNQPQVSIFPAEMTTALYRWAIASAWRQKMLNETGNDQYGPHSL
                     TVERIEMAIALHIECALINEYGEAQGAAAALALLTDMLEPSLLTAPPVLTARGCEVMA
                     EMYRTLPAAFDVCCSTGVTLYQGEV"
     gene            complement(5708..5992)
                     /locus_tag="RN951_004100"
     CDS             complement(5708..5992)
                     /locus_tag="RN951_004100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529019.1"
                     /translation="MNISNGHNGAQGQTLPEKHNTGAFAYGLSEDGFGKLTRARNACD
                     MLQLLFSEYPSQAGALDAGFAPGVAALMEYLRADLTDIAHSCALIEGGAR"
     gene            complement(6024..6383)
                     /locus_tag="RN951_004101"
     CDS             complement(6024..6383)
                     /locus_tag="RN951_004101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529020.1"
                     /translation="MRNYPHPGERWQHERGWTVTIIRLIEASPSVALVNPEFSCEVLI
                     RHDSDNQLSSCPLAWFEQRYTRLFDVPLFKPAPAPAGGSGSGPLTLHPSVLFIRWRER
                     SIWCSAEPDDGHYSKFL"
     gene            complement(6376..6552)
                     /locus_tag="RN951_004102"
     CDS             complement(6376..6552)
                     /locus_tag="RN951_004102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006120337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host cell division inhibitor Icd-like protein"
                     /protein_id="HDX2529021.1"
                     /translation="MAKQKCTWLFAAINRSQRNARPVMLRITADNERSARRRLAPDYV
                     LSFAGRIPCGGEHA"
     gene            complement(6913..7128)
                     /locus_tag="RN951_004103"
     CDS             complement(6913..7128)
                     /locus_tag="RN951_004103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family phage regulatory protein"
                     /protein_id="HDX2529022.1"
                     /translation="MTLKTYPITGHARPRATADFLQISTVTLWRWEKNNPEFPKSIRI
                     SKRVSVYDAQEIRQWVKAQSAGLEEVV"
     gene            complement(7231..7994)
                     /locus_tag="RN951_004104"
                     /pseudo
     CDS             complement(7231..7994)
                     /locus_tag="RN951_004104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001164862.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1853 a         2138 c         1934 g         2069 t
ORIGIN      
        1 aaatatgaac attgttaacg gtcgagggaa aatgctctag ttcctgcctt catgcttctc
       61 aaagtgtctt aggtgtaaat agctgatatc ttgtgtgaaa tgttatcttg ttgtaaatgg
      121 atttgcaatg ttaactcatg taaaaaatag atcattgtca taaaaaatga agtgtctgca
      181 agttaatagg tcagaacgca tgtaatcata aacggaacaa aaaacatagc agaaataatg
      241 tccgagttat ctactgacat aactaaaaaa ataatctaag tctcgtcatt tcagatagct
      301 taggaggcta atatccatac ccgaatcata ggatttccgt tgataggtag catataagaa
      361 tgagagaaaa tcagctgaga gcgcattaac cgatagtggt ggacttatcc agtttgattg
      421 atacaacgaa actgataatg atagtcggtt aaggtagttt agcgcacagc cccgcacgcc
      481 tgcccgcttc gcttaacaga ctggttttca tgcatgccat aaatcgtctc agttaccacc
      541 atacaaaggt tttcgcctca aaaaaggtgc ataagactca tgcgttttca tgcgccatag
      601 acatgcactc atgcgctctc aggccagcca gggaaaaggt gttaaaaatc ccggcactcg
      661 accgggatta cgtgggcgtt ttttctaatc agacaggaat ctgctgacgg cttgacagtt
      721 ttgacgcgga gccatagcga ttgagcgttt gctgttgttt taccggggtt tgtgatttgt
      781 ctggttcctg ttcattgcgc cggggtttca tgattatctt atccacactc tccagtgccg
      841 taaatgtgca ggaacattcc agattctggc actgatacca cgagcgttta actgacggag
      901 cttcataggc tgctgttctg gcgtgtgcaa ctgtaccgca ttccggacat ttaagtgcca
      961 ttaatatcac tcctgtatat cgttaatgtc attcaggcgt tgctgaaaac gcaggtgttg
     1021 tgccggggtg taagagccct ggcaatcacg aatcatcccg gggtcaggca tcaaaccgga
     1081 ttcatctagg atctcacgat aatccccgac aatttcaggc ggtgttattg ccagctggcg
     1141 aaccagagca ctgcgtaata tacgaaacgc aacgtcaacc cctccgcgtc ccttcaggaa
     1201 cggagccagt gcagatgtca gggctgcccc attcgcctgc ataaaattgc tgagagcagc
     1261 ttctgtgcag gcctccatca ataaatgctg cgagtaaatg cattcgcgcg cagcacagtt
     1321 aatttgccat ttcagcacat ccagacgttc ccgcagtaat tcgagctgtc gggcataatc
     1381 tgctggtttt tctgtggcag tgaggagaga tgctatctgt tgttcaacgg cttttcggct
     1441 ctcactatgt ccggcccaca gaatacgggc attccgaaaa ctggtaagtg cctggtcagg
     1501 tgtgcctcgg gccgtcatac tgctttctcc ttctcagcaa gttcctgacg aacctttatt
     1561 ttatgcatag ctgccggaga gagttgatta ctgaaatcca gacgcgccgc ataatccggg
     1621 gcaactcccg ccagtttaaa caccgggtcc tgttcaggca tcgcatcgtt agccagagcc
     1681 ggtctggtga tatgtttatg aataaagtct ttcagcactg tgtccgggtc attaactgaa
     1741 ttcaccacac ccacaacggc actggcttcc cggcccattg tggatttaag caggctcagc
     1801 gtctgaataa gcgcttttcc atgcgactgc ataaaatctt cccagatttg ttttgcgcga
     1861 atatctacaa ggatgttatg cgcgtggata tactttccgg ctaattccgc agctttctgc
     1921 ggcaaaagtg cattttcgct ttcctgagcc gccagcagct catcaaaatc ctcaagcgtt
     1981 tctcgtccca gcgcaatttc cgtgcgcagt tttttcattt cctttgagac cacgccctga
     2041 ctttcacgaa acagcgtgcg ccactcctca ttcagtgtgt tcgtcgtggc ttccatttca
     2101 gcgcgacgct ggcggattgt cgcaatatta tccgctgccg ctttctgctg acgacgtgct
     2161 tcaagccatg cgtttctggc tgtgttcatg gtttccagtg cccgctgcgt tacagccgga
     2221 aaagtggaaa ggttgttatt cactgcggtg ttgttcatga cttctcctgt cggggtggtt
     2281 agttacgtca attgtgtcgt ggctgacaca agcacactat cggtgctcag tgtgtggtgg
     2341 ctggcacaac gggcgcttgc ggttattccg acgtggctat gaaagccagc cagataaaaa
     2401 tgcccactgt ttcagtctgc tttatgtccc tgatgcggtg gaacaggtga aacatgtgtt
     2461 acacctttgt tttataaagc atttatatac actgcaccgg tggaacatcg cgggtaacaa
     2521 ggtggaacag cggattggct ggcgttacat ctgttccacc tcactatttc agaaggtgga
     2581 acaggttcag ccctgtaaaa tacggttgtt ccacctgttt cacctgttac ccttaataaa
     2641 taagactcac gcaaagtctt aacccggcac ctcgctgttg aagacataga gcctgcgggg
     2701 attcatctct ggcgggcgaa tggttgtctg gagtttgcca tcagtggagg gcagcaggta
     2761 tccacgatct gcgcacagac gcgccacctt gcgcgggtca aatcccctgc agatttcttt
     2821 ccagccggac ggcatgacat agaacgtagt gacagcttcc gtgccctgcg cggtactgcc
     2881 tttctccacc ctgcgccagc ccaccatatt gccggggcgg ttgcgctcgt cataccagtc
     2941 tgcaaagcgg ctgtactgat tcgcggtaaa gaaactgcga acctgctcca gtgcggcgat
     3001 atcttcctga ttggcggtgt gcccgcgatc tttcagccat gcgttcaggc agacgcgggt
     3061 tgcccgcagt gcttcaccct caggccagcc ggtgataccc agacgggttg ccagttcacc
     3121 tgccatcgcc accagtgcaa agcggttcac agcccgtccc acctgattgc ctgcatcttt
     3181 cggagtcagg gcggcagcat attccttcat cagcgatttt gcctgtgccg ttagtccgtt
     3241 aagatcagcg gtcagtgctt tcagccactc ccggaacggc gaaccgtagt agcaggacgt
     3301 ggcccattca agatgctctg ccagagcctt gccgctgtcg aagccgtgca gctcctcaaa
     3361 aacgccaaac ttcccggaat cgctggggat ctggatcatc ctgacttcca tcccggcaaa
     3421 agtacgctca ccggcctttg ccgcatgttc ggtcagagac aattcgccag ttgaaaagaa
     3481 caacaggcgc cactgcttac gggtacgcag ctcaccgtcc gtaccggcac ggcccttgcc
     3541 ctgaccgttt gccagcatgt aggcgatatt gcctgcctcg cgtccgtcaa cttcccggat
     3601 ctcatcaagc atcatggcgg catcgttgcg gcggctggcg catccctcca gcgcgttgcc
     3661 ggtggcccgc catgtctgcc agtagtcagg cccgccgcag acggaggttg ccgctttcat
     3721 ggtggtagtc ttaccgtctg tcgattcccc tttgaggtgg tagccgccgc cgtccatacc
     3781 caccagccgt aacagtggtg cagcaaaggc caggctgaca gcaaatgcca cgcgggagtt
     3841 gccggtacag tagcgggata catgctcccg ccattcctct gttgtgcccg acacgcggaa
     3901 atcacgcccc tgcacggaag tggtctggag aatgacaccc tctgcacctt caccgctgac
     3961 ctcatcctgc aggacgtaaa cctgaccatg ccagccagta cgactgacgc aggtcacgcg
     4021 gcgttccggt ttacacagtg agatatattc catcaggcgt gcgcgtgcct caccggtggt
     4081 gctgatataa gacagcccgt taaccagcag tacccggcgc agttcctcac cactgccgct
     4141 cagcatttcc atcggcatcg cccagcggcg acactcaccc cacgtatctt cccattccag
     4201 cagtcgtccg aagttaccgc catcggcatc gcaggtgatt gccgtcacac gcagcgggct
     4261 gcatattttg acgttctgga tctccgtctc accgttgcgc tgtacctgct tttcatacca
     4321 gagatattcc tgggtaagac ggaacccgtg cggcagttgc gtgcggcctt ccccgcacag
     4381 taccagaccg ttgcgaaagg cttcacgggc acgggtaata ccatgctccc gatgaaagtc
     4441 attccagtca gccttaatct ctcctggtgg cagcgtcatc cagccgccaa cagattttgc
     4501 cgcccgttca gcaaaggctc tgccgggatt ctcccccccg tcctgaaaat cgttatcacc
     4561 ggcgatgata atttttacct caggccagcg tgcccgcagc gactgcgcca cattgggcag
     4621 attgcccgca gatatggcag ccactacgca tccggcagtg agctggctta ccgtcagcgc
     4681 cgtagcgtaa ccttcggtaa tcaccacctg taccggtggt tcagacggta acgggctgag
     4741 cgacacaaac gcgcctttca tcgtgctgcc gggcagtatg cttttttcac ccgtcggggc
     4801 gataagctgt gcaccggtca cggctccggt attggtcgtg agtggtaaca gcagggaacc
     4861 ggcaggaaaa tccttaccgc tgatatgctg cacgcttccg gtcagagagg ccgggtatcc
     4921 ggcgaaccct tttcctgtca gataggcgct ttctcccgtg tggctctctt tcatcagcgc
     4981 cgccacggta agacccatgt cgcgtttagg ggctttttgt ctggcaggct taacaggcag
     5041 ttcctgcaca tccggcacat taagcatctg cgccacctcc tgcgcagcct ttctgacgct
     5101 gtaaccggtt acgagcttaa ccagatccag accgtcacca ttgccacact ggctgcagat
     5161 ccacgtcccg cgcccgtcaa ggtcatcaag gcgaaaacga tccttgcccc cacatttcgg
     5221 gcagggaccg tgcctgccgt tttcaggtac atcaatacgc agcatctgca gaataacggg
     5281 ccatttcccc cgcgcggcgg ctgaaatctg cgtaaccgtc tgtattgtca tacttccccc
     5341 tgatacaacg tcacaccggt actgcagcag acatcaaagg ccgccggaag cgtgcggtac
     5401 atctccgcca ttacttcaca accgcgcgcg gtcagtaccg gcggcgcggt cagcagtgac
     5461 ggctccagca tgtcagtcag cagtgccagc gcggcagcgg cgccctgtgc ttcgccgtac
     5521 tcgttaatca gtgcgcactc gatatgcagc gcaatggcca tttcaatacg ctccaccgtc
     5581 aggctgtgcg gaccatactg atcattgcca gtttcgttca gcattttctg ccgccatgct
     5641 gaagcaatag cccaccggta aagcgcggtg gtcatttctg ccgggaaaat ggaaacctgc
     5701 ggctggttca tctggcacct ccttcaatca gtgcgcagct gtgtgcaata tccgtcaaat
     5761 ctgcccgcag gtactccatc agcgcggcga caccaggcgc aaagcctgcg tccagtgctc
     5821 cggcctgaga cgggtattca gaaaagagaa gctggagcat gtcgcaggca tttcttgcgc
     5881 gggtcagctt tccgaaaccg tcctctgaca acccataggc aaaagcaccg gtattgtgtt
     5941 tttcaggcaa agtctggccc tgagcaccgt tgtgcccgtt tgaaatattc attgtggatt
     6001 actccgtttt cagcggtgtt ttgtcagaga aactttgaat agtgaccgtc atcaggctca
     6061 gcagaacacc atatgctacg ctcccgccag cggataaata gcacagacgg atgcagtgtc
     6121 agcgggccgg aaccactacc gcctgcagga gctggtgcag gcttaaagag cggtacatca
     6181 aacaggcgcg tatatcgctg ttcaaaccat gccagagggc aggaagaaag ctggttgtcg
     6241 ctgtcatgac gtatcagcac ttcacagctg aattcaggat taaccagcgc cacagagggc
     6301 gaggcttcta ttaatcggat aatcgtgacc gtccagccac gttcatgctg ccagcgttcg
     6361 ccgggatgcg gataattacg catgttcacc tccgcaggga atgcgcccgg caaagctcag
     6421 tacatagtcc ggggcaagtc tgcgccgcgc tgatcgctcg ttatctgcgg tgatccttaa
     6481 cattaccgga cgggcattac gttgactgcg gttgatcgcc gcaaataacc aggtacactt
     6541 ctgtttagcc atcttcgtta cctcatataa cgtgctggtc agacgcctcg gtggtgctgc
     6601 aaacactccg gggcgttgct attttgtttt tctgtgtgta atgtgtcatt acacataaat
     6661 acattacaat gggtgtaatt gacgtgtcaa cacacaaaaa tgaaagacgt gggaatccgc
     6721 cattccagtt ccgacttgac cctgaactgc gtgaactgat ggaacaagca caacagcagg
     6781 atggcgatga atcgctagcg gcttggatca agcgcattct acgcaaagag ttacaaagcc
     6841 gaggtttaga accaaagaat tgattaatac gttggggagg cttttttctc cccagctttg
     6901 ttaatattgt cattacacta cttcctccaa tcctgctgat tgagctttaa cccactgcct
     6961 aatttcttgt gcatcgtaaa cagatacccg ttttgaaatg cgtatagatt tgggaaattc
     7021 aggattgttc ttttcccagc gccagagagt aaccgtactt atttgcaaaa agtcagcagt
     7081 agctcgtggg cgggcatgtc cagtgatagg ataagttttt aatgtcatga aattacctgc
     7141 cgtgttatgt aatgaacacg gcagatacta tggggatatc aaaatgctgt gaaggtagtg
     7201 taatcaactc tacctgtaga ttgtttcagt ctaccccttt tgttttaatc ccgcatgatt
     7261 aaccgctaat cgtaattttc ttaagatttc ttgttcatta gtgataaata ttggaggtag
     7321 ctctcctaaa tgtttaatta tggcgttagt ccacttttca ggacttatct cttttctttc
     7381 accacgacat tcgcttgggt attttgctaa tatatatatg gctgcattta ataacccccc
     7441 ctattttttg catgatgctc agcagtgtta tttaatcgct tggggatttt aggttcagat
     7501 gaaattcttt tcgtaagtaa acttggcata ggaattccag tttttactga tttccatatt
     7561 aactctaaat ctcttcgcat gataagaaga tcttcaaatg gaatatcaat gaccttattt
     7621 ccttcatatg aggccgttgc catcaaaaca ttatctcgta tttttaccgg tttaagcctg
     7681 aattcataat ctggatctat agctaatcca ttttttatgt cacttatcat atcatcggcg
     7741 taccaaatac cacaggcaaa tcctataatt tgaagcccat tttcaaaatg ttcaaaggag
     7801 tcatctttaa ggtcatacca tattgttgaa aattccatct ctagtgattg attagttaat
     7861 acgggatgaa ttaagtcaat ttccattttc tgatttttat agaggaaatt aacattaaat
     7921 ctaactgcaa gtccatccgc cttgaatgcg atattaaaag cgcctatttc gtataggtgt
     7981 aataaatcat caat
//
LOCUS       DAPOAV010000141         7917 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.142, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000141 DAPOAV010000000
VERSION     DAPOAV010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7917
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.142"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..2685)
                     /locus_tag="RN951_004105"
     CDS             complement(<1..2685)
                     /locus_tag="RN951_004105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HDX2529023.1"
                     /translation="MHSWKKKLVVSQLALACTLAITSQANAANYDTWTYIDNPVTALD
                     WDHMDKAGTVDGNYVNYSGFVYYNNTNGDFDQSFNGDTVNGTISTYYLNHDYADSTAN
                     QLDISNSVIHGSITSMLPGGYYDRFDADGNNLGGYDFYTDAVVDTHWRDGDVFTLNIA
                     NTTIDDDYEALYFTDSYKDGDVTKHTNETFDTSEGVAVNLDVESNINISNNSRVAGIA
                     LSQGNTYNETYTTESHTWDNNISVKDSTVTSGSNYILDSNTYGKTGHFGNSDEPSDYA
                     GPGDVAFTSTWNSNFDPNGHDSNGDGVKDTNGGWTDDSLNVDELNLTLDNGSKWVGQA
                     IYNVAETSAMYDVATNSLTPDATYENNDWKRVVDDKVFQSGVFNVALNNGSEWDTTGR
                     SIVDTLTVNNGSQVNVSESKLTSDTIDLTNGSSLNIGEDGYVDTDHLTINSYSTVALT
                     ESTGWGADYNLYANTITVTNGGVLDVNVDQFDTEAFRTDKLELTSGNIADHNGNVVSG
                     VFDIHSSDYVLNADLVNDRTWDTSKSNYGYGIVAMNSDGHLTINGNGDVDNGTELDNS
                     SVDNVVAATGNYKVRIDNATGAGAIADYKDKEIIYVNDVNSNATFSAANKADLGAYTY
                     QAEQRGNTVVLQQMELTDYANMALSIPSANTNIWNLEQDTVGTRLTNSRHGLADNGGA
                     WVSYFGGNFNGDNGTINYDQDVNGIMVGVDTKIDGNNAKWIVGAAAGFAKGDMNDRSG
                     QVDQDSQTAYIYSSAHFANNVFVDGSLSYSHFNNDLSATMSNGTYVDGSTNSDAWGFG
                     LKAGYDFKLGDAGYVTPYGSVSGLFQSGDDYQLSNDMKVDGQSYDSMRYELGVDAGYT
                     FTYSEDQALTPYFKLAYVYDDSNNDNDVNGDSIDNGTEG"
     gene            3209..4183
                     /gene="hemB"
                     /locus_tag="RN951_004106"
     CDS             3209..4183
                     /gene="hemB"
                     /locus_tag="RN951_004106"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308450.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HDX2529024.1"
                     /translation="MTDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDY
                     KAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARM
                     SRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGAD
                     FIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKS
                     YQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEY
                     AMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR"
     gene            complement(4290..5141)
                     /gene="tauD"
                     /locus_tag="RN951_004107"
     CDS             complement(4290..5141)
                     /gene="tauD"
                     /locus_tag="RN951_004107"
                     /EC_number="1.14.11.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine dioxygenase"
                     /protein_id="HDX2529025.1"
                     /translation="MSERLSITPLGPYIGAQISGADLTRPLSDNQFEQLYHAVLRHQV
                     VFLRDQAITPQQQRALAQRFGELHIHPVYPHAEGVDEIIVLDTHNDNPPDNDNWHTDV
                     TFIETPPAGAILAAKELPSTGGDTLWTSGIAAYEALSVPFRQLLSGLRAEHDFRKSFP
                     EYKYRKTEEEHQRWREAVAKNPPLLHPVVRTHPVSGKQALFVNEGFTTRIVDVSEKES
                     EALLSFLFAHITKPEFQVRWRWQPNDIAIWDNRVTQHYANADYLPQRRIMHRATILGD
                     KPFYRAG"
     gene            complement(5138..5965)
                     /gene="tauC"
                     /locus_tag="RN951_004108"
     CDS             complement(5138..5965)
                     /gene="tauC"
                     /locus_tag="RN951_004108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter permease TauC"
                     /protein_id="HDX2529026.1"
                     /translation="MSVLINEKLHSRRLKWRWPLSRQVTLSIGTLAVLLTVWWTVATL
                     QLISPLFLPPPQQVLEKLLTIAGPQGFMDATLWQHLAASLTRIMLALFAAVLFGIPVG
                     IAMGLSPTVRGILDPIIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS
                     ALAGVKSVQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAE
                     LIAATRGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ"
     gene            complement(5962..6729)
                     /gene="tauB"
                     /locus_tag="RN951_004109"
     CDS             complement(5962..6729)
                     /gene="tauB"
                     /locus_tag="RN951_004109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter ATP-binding subunit"
                     /protein_id="HDX2529027.1"
                     /translation="MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSSCGKTTLL
                     NLIAGFVPYQHGSIQLAGKRIEGPGAERGVVFQNEGLLPWRNVQDNVAFGLQLAGIEK
                     MQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALD
                     AFTRDQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSSGPGRVLERLPLNFA
                     RRFVAGESSRSIKSDPQFIAMREYVLSRVFEQREAFS"
     gene            complement(6742..7704)
                     /gene="tauA"
                     /locus_tag="RN951_004110"
     CDS             complement(6742..7704)
                     /gene="tauA"
                     /locus_tag="RN951_004110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414899.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter substrate-binding
                     protein"
                     /protein_id="HDX2529028.1"
                     /translation="MAISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNT
                     FAKESGATVDWRKFDSGASIVRALASGDVQIGNLGSSPLAVAASQQVSIEVFLLASKL
                     GNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPA
                     IIAAWQRGDIDGAYVWAPAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHP
                     EVVKAFAKSAIDAQQPYIANPDVWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQ
                     QQTAELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQYVTSRFVQ"
BASE COUNT         2000 a         2078 c         1880 g         1959 t
ORIGIN      
        1 cccttcagta ccgttatcga tggaatcgcc gttcacatcg ttatcgttgt tagagtcgtc
       61 gtagacgtaa gccagtttga agtacggagt cagagcctga tcttcgctgt aggtgaaggt
      121 ataacctgca tctacaccca gttcataacg catgctgtcg taagactgac cgtcaacttt
      181 catgtcgttg ctcagctggt agtcatcacc agactggaac agaccagaaa cgctgccgta
      241 aggagtcacg taaccagcat cacccagttt gaagtcgtaa ccggctttca aaccgaagcc
      301 ccaagcgtcg gagttggtgc taccgtcaac gtaagtaccg ttgctcatgg ttgcagacag
      361 gtcgttgttg aagtgagagt agctcaagct accatcaaca aagacgttgt tcgcgaagtg
      421 agcagaagag tagatgtagg cagtctggct gtcttgatcc acctgaccag aacggtcatt
      481 catgtcacct ttagcgaagc ctgcagccgc accgacgatc cacttagcgt tgttaccgtc
      541 aattttggta tcaacaccga ccatgatgcc gttaacatcc tgatcatagt tgatggtgcc
      601 gttgtcgccg ttgaagttac caccgaagta gcttacccat gcgccgccgt tatcagccag
      661 gccatgacga gagttggtca gacgagtacc aacggtgtct tgttccaggt tccagatatt
      721 ggtgttcgca gacgggatgc tcagcgccat gttagcgtag tcggtcagct ccatctgttg
      781 cagaacaacg gtgttaccgc gctgttcagc ctgataggtg tatgcaccca ggtcagcttt
      841 gttagcagca gagaaggtcg cgttgctgtt gacgtcgttt acgtagataa tttctttatc
      901 tttgtaatca gcgatagcgc cagcgccagt tgcgttgtcg atacgaactt tgtagttacc
      961 ggttgcagca acaacattgt ctacagagct gttatccagt tcagtaccgt tgtctacgtc
     1021 gccgttaccg ttgatagtca ggtgaccatc agagttcata gcaacaatac cgtaaccgta
     1081 gttagacttg gaagtatccc aggtacggtc gttcaccaga tcagcgttca gaacgtaatc
     1141 gctgctatgg atatcgaaca caccagatac tacgttaccg ttatggtcag cgatgttgcc
     1201 gctggtcagt tccagtttgt cagtacggaa agcttcagta tcgaactgat caacgttcac
     1261 atccaataca ccgccgttag ttacggtgat agtattggcg tacaggttgt aatcagcccc
     1321 ccacccagta gattcggtca acgcaacagt actgtaggag ttaatagtca gatgatcggt
     1381 atcaacgtag ccatcttcac caatgttcag cgaagaaccg ttagttaaat cgatagtatc
     1441 tgaagttaat ttagattccg aaacattaac ctgagaacca ttattaactg tcaaggtatc
     1501 aacgatggaa cgacctgtag tatcccattc agaaccgtta ttcaacgcta cgttaaatac
     1561 accgctctgg aagaccttgt catcaacaac acgtttccag tcattgtttt catatgttgc
     1621 atcaggagta aggctgtttg tagcaacatc atacattgct gacgtttcag caacgttata
     1681 aattgcctga ccaacccact tgcttccgtt atcgagagtg agatttagtt catcaacgtt
     1741 gaggctatca tcagtccaac ccccgttggt atctttcacc ccgtcaccgt tggaatcatg
     1801 accattcgga tcaaaattac tattccaggt gctggtaaag gcaacatcac ccgggccagc
     1861 ataatcactc ggttcatcag aattgccaaa gtgaccagtt ttgccataag tattgctatc
     1921 caggatataa tttgaacccg aagtcactgt ggaatctttt acagagatat tgttatccca
     1981 agtatgagat tcggtagtgt aggtttcgtt gtaagtatta ccttgagata atgcaatacc
     2041 tgcaacgcgg gagttattgg aaatattgat gttactttct acatcaagat taacagcaac
     2101 gccttcactt gtatcaaatg tctcatttgt gtgcttggtt acatcaccat ctttataaga
     2161 atcagtgaag taaagagctt cataatcatc atcaatagta gtgttagcaa tgttcaaagt
     2221 gaaaacatca ccatcacgcc agtgtgtatc aacaaccgca tcagtgtaaa aatcatatcc
     2281 acccagatta ttaccatctg catcaaaacg atcataataa ccgccaggca gcatagaagt
     2341 aatcgaaccg tgaatcactg aattactgat atcaagctga ttagcagtac tgtctgcata
     2401 atcatggttc aaataatagg ttgagatcgt gccgttaacg gtatcgccgt taaaggactg
     2461 atcgaaatca ccattggtgt tgttgtaata gacaaaacca ctatagttta catagttgcc
     2521 atctacagtg cctgccttat ccatatgatc ccaatcaagt gctgtaacgg gattatcgat
     2581 ataagtccag gtatcatagt ttgctgcatt agcctgagag gtgatagcca gagtgcaagc
     2641 caatgctaat tgtgatacta caagtttctt tttccaggag tgcatttgtc atccctcctc
     2701 agggacgtaa taagttgatc catcaattat caatgcatag aaaacatatt atgtttcgcg
     2761 ctaacgatta tgctgcgtta cagacgaatg gttcaattat tctttcccct aagtccgaat
     2821 gtggacatat ataatttatg gagaaaaaca cgcatcaaat tcataaaagc acagtatttc
     2881 aacatgttgc agataatttt gtttttgaag catacgcata ataaatatca caaacacaaa
     2941 ccagataaat atcctatgaa tatgcaacaa agttttaatt attcaattta tagcagcgca
     3001 accaaactcc aaaaaataat aaccaacagc tataaataaa gattaaaaat attttcagtg
     3061 aatataaaat tattgctgtt tctattaaaa agatgtcctg gcctctcttc cattctcttc
     3121 ttgtcaacat cgcgacaact ttcgtaaaac atccctaccc tgcttcaggt atactatgcc
     3181 cctcgattcc acaaacatca ggcagaccat gacagactta atccaacgcc ctcgtcgcct
     3241 gcgcaaatct cctgcgctgc gcgctatgtt tgaagagaca acacttagcc ttaacgacct
     3301 ggtgttgccg atctttgttg aagaagaaat tgacgactac aaagccgttg aagccatgcc
     3361 aggcgtgatg cgcattccag agaaacatct ggcacgcgaa attgaacgca tcgccaacgc
     3421 cggtattcgt tccgtgatga cttttggcat ctctcaccat accgatgaaa ccggcagcga
     3481 tgcctggcgg gaagatggac tggtggcgcg tatgtcgcgc atctgcaagc agaccgtgcc
     3541 agaaatgatc gttatgtcag acacctgctt ctgtgaatac acttctcacg gtcactgcgg
     3601 tgtgctgtgc gagcatggcg tcgacaacga cgcgactctg gaaaatttag gcaagcaagc
     3661 cgtggttgca gctgctgcag gtgcagactt catcgcccct tccgccgcga tggacggcca
     3721 ggtacaggcg attcgtcagg cgctggacgc tgcgggattt aaagatacgg cgattatgtc
     3781 gtattcgacc aagttcgcct cctcctttta tggcccgttc cgtgaagctg ccggaagcgc
     3841 attaaaaggc gaccgcaaaa gctatcagat gaacccaatg aaccgtcgtg aggcgattcg
     3901 tgaatcactg ctggatgaag cccagggcgc agactgcctg atggttaaac ctgctggagc
     3961 gtacctcgac atcgtgcgtg agctgcgtga acgtactgaa ttgccgattg gcgcgtatca
     4021 ggtgagcggt gagtatgcga tgattaagtt cgccgcgctg gcgggtgcta tagatgaaga
     4081 gaaagtcgtg ctcgaaagct taggttcgat taagcgtgcg ggtgcggatc tgattttcag
     4141 ctactttgcg ctggatttgg ctgagaagaa gattctgcgt taattttgtt tcctctcaga
     4201 aagggggagt taacctgttg aaagtacggt gaacgccccc tcaccctaac cctctcccca
     4261 agggggcgag gggaccgtcc actctcgtat taccccgccc gataaaacgg tttatcccca
     4321 aggatcgtcg cccgatgcat tatccgtcgc tgtggcaggt aatcggcatt ggcatagtgc
     4381 tgggtcacgc ggttatccca aatcgcaata tcatttggtt gccagcgcca gcgcacctga
     4441 aactccggtt tggtgatatg ggcaaacaaa aaacttaaca aggcttcgct ctctttctcg
     4501 ctcacatcaa caattcgcgt agtaaagcct tcattcacaa acagcgcctg tttaccgctc
     4561 accggatgcg ttcgcaccac cggatgtagc aacggcgggt ttttcgcgac cgcctcgcgc
     4621 cagcgttgat gttcctcctc ggttttgcgg tatttgtatt ccgggaacga tttacggaaa
     4681 tcatgctccg cacgcagccc actcagcagc tggcggaagg gaacagagag cgcctcatag
     4741 gccgcaatac cgctggtcca gagcgtatca ccgccggtcg aaggtaactc tttagctgcc
     4801 agaatcgccc ctgcgggtgg cgtttcaata aatgtcacat cggtatgcca gttgtcgtta
     4861 tctggcggat tatcgttatg ggtatccagc acgatgatct cgtcaacccc ttcggcatgc
     4921 gggtaaacag ggtgaatatg caattcgcca aaacgctggg ccagcgcgcg ttgctgctgc
     4981 ggcgtaatag cttgatcgcg tagaaacacc acctgatggc gcagcaccgc atggtaaagc
     5041 tgttcaaact gattatcgct taacgggcgc gtcaggtcgg cacccgaaat ttgtgcgccg
     5101 atatacggcc ccagcggggt aatgctcaga cgttcactca ttgtacttct ccatgccagg
     5161 gcgtcaggcg gcgctgtaac gcgcgcagac ccagttctaa aagaaaggcg ataatcgcaa
     5221 tcaccgcgat ccccgccagc accacgtcag ttgcgagaaa ttcacccgct gactgaacca
     5281 taaatcctaa accgcgcgtc gcggcaatca gctccgccgc caccagcgta gaccagccca
     5341 cccccagacc aatacgtaat ccggtgagga tttccggcag cgcaccgggc aaaatgacaa
     5401 accacagcac ctgcgcacgg ctggcaccca gcgactgggc ggcacgaatg cgaacctgct
     5461 gcacgctttt cacccccgcc agcgccgaca tcgccaccgg tgcaaaaatc gctaaataga
     5521 tcagtaagat cttcgaggtt tcaccaatac caaaccagat caccatcagc ggcaaataag
     5581 ccagcggcgg caccggacga taaagctcga ttatcggatc cagaatgccg cgtaccgtag
     5641 ggctaagtcc catcgcgatc ccgaccggaa taccgaacaa caccgctgca aatagcgcca
     5701 gcataatgcg cgtcagactg gctgccagat gctgccacag cgtggcgtcc ataaagcctt
     5761 gcggtccggc aatggtgagt agtttttcca gtacctgttg cggcggcggc aaaaatagcg
     5821 ggctaatcag ttgcagcgtc gccaccgtcc accatacggt gagtaaaacc gctaacgtgc
     5881 caatgcttaa ggtcacctga cgcgagagcg gccagcgcca tttcagccgc cgcgaatgca
     5941 gtttttcatt aatgagcaca ctcatgagaa cgcctcccgt tgctcaaata cgcggcttaa
     6001 aacatattcg cgcatggcga tgaattgtgg atcggacttg atgctgcggc tcgactctcc
     6061 cgcaacaaag cggcgagcaa agttgagcgg cagccgctcc agcacacggc cagggccgga
     6121 tgaaagcaga accagttcag tcgccataaa caccgcttct tctatatcgt gggtaatcaa
     6181 cagcacctgc ttgcccgtct cctgccagag tttcagcagc agggtttgca tctggtcgcg
     6241 ggtgaaggcg tccagcgcac caaacggttc gtcgagtaat aacagctggg gattcgccgc
     6301 cagcgcacga gcaatcccca cccgctgacg ttgaccaccg gaaagctgcc agatgtagcg
     6361 tttttctgcg ccttccagcc ccactttttt cagcatctgg tgcgcgattt ccagtcgctg
     6421 cattttctct atacctgcca attgcaggcc gaacgccacg ttgtcctgta cattgcgcca
     6481 cggtagtagc ccttcattct gaaaaactac gccacgctct gctcccggtc cctcaatacg
     6541 cttacccgcc agttgaatgc tgccatgctg ataaggcaca aaaccggcaa tcagattcag
     6601 cagggtggtt ttaccgcagc tggacggccc cagcaccacc agtagctcgc cgctttccag
     6661 cgtcaggttg atatcttcca gtgccggttt gccgccataa tcggcgtaaa gatgagagat
     6721 ttgcagcatc tgcgcctcct tttattgcac gaagcgcgag gtaacgtact ggctgtaatc
     6781 attcgctaca gccgggacct tgccctgctc tttcaaaaac tgcgcggtgt cgatgatcgc
     6841 tttgttcacc ggtccggtca gttctgccgt ttgttgctgc ggcgtcagat aggtattccc
     6901 cttcaccagc cccggaacgt caccttcagg cacgccgctt aaacgcgcca gtttgctgat
     6961 gttttccggc tgtttcagcc acacgtctgg gttagcaatg tacggttgct gagcatcgat
     7021 ggcgctttta gcgaacgctt tcacgacctc aggatgtttc tcggcaaaat ctttgcgcac
     7081 cacccagacg tccagcgttg gcgcgcccca ctgcccgacc tgttcagaat cggtcaacac
     7141 cttgccgtct ttttccaggg cgttaaccgc cggtgcccag acataagcac catcaatatc
     7201 tcctcgctgc caggcagcga taatcgcggg cggctgcagg ttcacaatct ccacttgccc
     7261 gggtttaatg ccccagtgtt tcagtgccgc cagcaggctg tagtgggtgg tggagataaa
     7321 cggtacggcg atgcgtttgc caatcagatc ttccggtttg ctgatagttt tctttaccac
     7381 cagcgcttcg gagttaccca gttttgacgc cagcaagaag acttcaatcg acacctgttg
     7441 gctggctgca accgctaacg ggctggaacc gaggttgccg atttgcacgt cgcctgaagc
     7501 cagcgcccgc acgatgctgg ctccgctgtc aaacttacgc cagtccacgg ttgctccgct
     7561 ttctttagca aaggtgttgt cggcctgagc cactttcgcc ggttcggctg aggtttgata
     7621 cgccacggtg acgttcaccg cctgtgcctg aaaagcgatg aatgccagtg cggcaagaag
     7681 tgtgttacgc gatgaaattg ccatgattgt ctgctcccct gtcttgttat gggagcagta
     7741 ttcaggaata aaaacattca ttaaaagaat tagtcgttat cgcacagatg attttattct
     7801 tagcaaaaaa acggctaagg aaagattaaa tatgcaatta ctccgttcta acaattggga
     7861 aaattactac acttcatttt agtgatgcat aaacaaccac attacgagat ttattac
//
LOCUS       DAPOAV010000142         7348 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.143, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000142 DAPOAV010000000
VERSION     DAPOAV010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7348
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.143"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            1..130
                     /locus_tag="RN951_004111"
     ncRNA           1..130
                     /ncRNA_class="other"
                     /locus_tag="RN951_004111"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
     gene            177..308
                     /locus_tag="RN951_004112"
     ncRNA           177..308
                     /ncRNA_class="other"
                     /locus_tag="RN951_004112"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
     gene            complement(492..1169)
                     /gene="narI"
                     /locus_tag="RN951_004113"
     CDS             complement(492..1169)
                     /gene="narI"
                     /locus_tag="RN951_004113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HDX2529029.1"
                     /translation="MQFLNMFFFDIYPYIAGAVFLIGSWLRYDYGQYTWRAASSQMLD
                     RKGMNLASNLFHIGILGIFVGHFFGMLTPHWMYEAWLPIEVKQKMAMFAGGASGVLCL
                     IGGVLLLKRRLFSPRVRATTTGADILILSLLVIQCALGLLTIPFSAQHMDGSEMMKLV
                     GWAQSVVTFHGGASQHLDGVAFIFRLHLVLGMTLFLLFPFSRLVHIWSVPVEYLTRKY
                     QLVRARH"
     gene            complement(1169..1879)
                     /gene="narJ"
                     /locus_tag="RN951_004114"
     CDS             complement(1169..1879)
                     /gene="narJ"
                     /locus_tag="RN951_004114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HDX2529030.1"
                     /translation="MIELVIVSRLLEYPDAALWQHQQEMFEAIAASKNLPKEDAHALG
                     IFLRDLTTMDPLDAQAQYSELFDRGRATSLLLFEHVHGESRDRGQAMVDLLAQYEQHG
                     LQLNSRELPDHLPLYLEYLAQLPQSEAVEGLKDIAPILALLSARLQQRESRYAVLFDL
                     LLKLANTAIDSDKVAEKIADEARDDTPQALDAVWEEEQVKFFADKGCGDSAITAHQRR
                     FAGAVAPQYLNITTGGQH"
     gene            complement(1876..3414)
                     /gene="narH"
                     /locus_tag="RN951_004115"
     CDS             complement(1876..3414)
                     /gene="narH"
                     /locus_tag="RN951_004115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HDX2529031.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTSREGVEYAWFNNV
                     ETKPGQGFPTDWENQEKYKGGWIRKINGKLQPRMGNRAMLLGKIFANPHLPGIDDYYE
                     PFDFDYQNLHTAPEGSKSQPIARPRSLITGERMAKIEKGPNWEDDLGGEFDKLAKDKN
                     FDNIQKAMYSQFENTFMMYLPRLCEHCLNPACVATCPSGAIYKREEDGIVLIDQDKCR
                     GWRMCITGCPYKKIYFNWKSGKSEKCIFCYPRIEAGQPTVCSETCVGRIRYLGVLLYD
                     ADAIERAASTENEKDLYQRQLDVFLDPNDPKVIEQAIKDGIPLSVIEAAQQSPVYKMA
                     MEWKLALPLHPEYRTLPMVWYVPPLSPIQSAADAGELGSNGILPDVESLRIPVQYLAN
                     LLTAGDTKPVLRALKRMLAMRHYKRAETVDGKVDTRALEEVGLTEAQAQEMYRYLAIA
                     NYEDRFVVPSSHRELAREAFPEKNGCGFTFGDGCHGSDTKFNLFNSRRIDAIDVTSKT
                     EPHP"
     gene            complement(3411..7154)
                     /locus_tag="RN951_004116"
     CDS             complement(3411..7154)
                     /locus_tag="RN951_004116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit alpha"
                     /protein_id="HDX2529032.1"
                     /translation="MSKFLDRFRYFKQKGETFADGHGQLLNTNRDWEDGYRQRWQHDK
                     IVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTDYPRTRPDLPNHEPRGCPRGASYSWY
                     LYSANRLKYPMMRKRLMKMWREAKALHSDPVEAWASIIEDADKAKSFKQARGRGGFVR
                     SSWQEVNELIVASNVYTIKNYGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFY
                     DWYCDLPPASPQTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGT
                     KTVAVTPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPSQYFTDYVRRY
                     TDMPMLVMLEERDGYYAAGRMLRAADLVDALGQENNPEWKTVAFNTNGEMVAPNGSIG
                     FRWGEKGKWNLEQRDGKTGEETELQLSLLGSQDEIAEVGFPYFGGDGTEHFNKVELEN
                     VLLHKLPVKRLQLADGSTALVTTVYDLTLANYGLERGLNDVNCATSYDDVKAYTPAWA
                     EQITGVSRSQIIRIAREFADNADKTHGRSMIIVGAGLNHWYHLDMNYRGLINMLIFCG
                     CVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETV
                     TAEELLSPMADKSRYTGHLIDFNVRAERMGWLPSAPQLGTNPLTIAGEAEKAGMNPVD
                     YTVKSLKEGSIRFAAEQPENGKNHPRNLFIWRSNLLGSSGKGHEFMLKYLLGTEHGIQ
                     GKDLGQQGGVKPEEVDWQDNGLEGKLDLVVTLDFRLSSTCLYSDIILPTATWYEKDDM
                     NTSDMHPFIHPLSAAVDPAWEAKSDWEIYKAIAKKFSEVCVGHLGKETDIVTLPIQHD
                     SAAELAQPLDVKDWKKGECDLIPGKTAPHIMVVERDYPATYERFTSIGPLMEKIGNGG
                     KGIAWNTQSEMDLLRKLNYTKAEGPAKGQPMLNTAIDAAEMILTLAPETNGQVAVKAW
                     AALSEFTGRDHTHLALNKEDEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNV
                     HELIPWRTLSGRQQLYQDHQWMRDFGESLLVYRPPIDTRSVKEVIGQKSNGNQEKALN
                     FLTPHQKWGIHSTYSDNLLMLTLGRGGPVVWLSEADAKDLGIADNDWIEVFNSNGALT
                     ARAVVSQRVPAGMTMMYHAQERIVNLPGSEITQQRGGIHNSVTRITPKPTHMIGGYAH
                     LAYGFNYYGTVGSNRDEFVVVRKMKNIDWLDGEGNDQVQESVK"
BASE COUNT         1632 a         2095 c         1924 g         1697 t
ORIGIN      
        1 tctgcccatg cggggaagga tgagaagctt cgactaaggt tcggctcgag cgtcagcgag
       61 agagcgttgc cgcaggcaac gacccgaagg gcgaagcgcg cagcgctgag taatccttcc
      121 cccaccacca tcactttcaa aagccccgga attctcaaac gaatccgcaa tcaaatattc
      181 tgcccaagcg gggaaggatg agaagcttcg accaaggttc gacttgagcg ccagcgagag
      241 agcgttgccg caggcaacga cccgaagggc gaagcgcgca gcgctgagta atccttcccc
      301 caccaccatc gcttccttaa ataatcaaaa cctgttactc cgagctaatt ttgcccgatg
      361 gcaccacgtt taccgggcct acaatatcct cccctgtagg tcggataagc gaagcgcatc
      421 cgacaactca ccccgcaccg tgcccataaa aaaaccccgc cgaagcaggg tctatgtgaa
      481 ctaaaattcg cttagtgacg agcgcgcacc agctggtact tacgtgtcag atactccacc
      541 ggtacgctcc agatgtgtac cagacgcgag aacgggaaca gcaggaataa cgtcatcccc
      601 agcaccaggt gcagacggaa gataaacgcc acaccatcga ggtgttgaga agcgccaccg
      661 tggaaggtca ccaccgactg cgcccagcca accagtttca tcatctcgct accgtccata
      721 tgctgagcgg agaacggaat ggtcaacagg cccagcgcgc actggataac gagcagcgac
      781 aggatcagga tatccgctcc ggtagtggtt gcacgcacgc gtgggctgaa cagacgacgt
      841 ttcagcaaca gcacgccgcc aatcagacac agcacgccgc tggcaccacc agcaaacatt
      901 gccattttct gtttcacttc aatcggcagc caggcttcat acatccagtg cggcgtcagc
      961 ataccgaaga agtgaccgac aaaaatcccc agaatcccga tatggaacag gttcgacgcc
     1021 aggttcatcc ctttgcgatc cagcatctgg ctggacgccg cgcgccaggt gtactgcccg
     1081 tagtcataac gcagccagct accaatcagg aagaccgccc cggctatgta cgggtagata
     1141 tcaaagaaga acatattcag gaattgcatt agtgctgtcc tccggtggtg atattcagat
     1201 attgcggcgc gacggcaccg gcaaagcgac gctgatgcgc agtgattgct gaatcaccgc
     1261 agcctttgtc agcaaagaat ttaacctgct cttcttccca gacagcatcc agcgcctgcg
     1321 gcgtatcatc gcgcgcttcg tcggcaattt tttccgccac tttgtcgctg tcgatagcgg
     1381 tattcgccag tttcagcagc agatcaaaca gcacggcata acggctttca cgctgttgca
     1441 gacgcgcgct cagcaatgcc agaatcggcg cgatatcttt caaaccttcc acggcttcgc
     1501 tttgcggcag ctgcgccagg tactccagat acagcggcag atggtccggc aattcgcggc
     1561 tgtttaactg caagccgtgc tgctcgtact gcgccagcag gtccaccatc gcctggccgc
     1621 ggtcgcggga ttcgccgtgc acatgttcaa acagcaacag tgacgtggcg cggccacggt
     1681 cgaacagttc gctgtactgc gcctgggcat cgagcggatc catcgtcgtt aaatcgcgca
     1741 ggaaaatgcc cagcgcatgg gcatcctctt ttggcagatt tttcgacgcg gcaatcgcct
     1801 caaacatctc ttgttgatgc tgccataagg cagcatccgg atattcaagg agacgcgata
     1861 caatcacgag ttcgatcatg gatgcggctc cgttttgctg gtcacatcga tggcatcgat
     1921 acgacggctg ttgaacagat tgaatttggt atctgaaccg tggcagccat caccaaaggt
     1981 aaagccgcag ccatttttct ccgggaaggc ttcccgtgcc agttcacgat gactactcgg
     2041 caccacaaag cgatcttcgt agttagcaat cgccagataa cggtacatct cctgtgcctg
     2101 ggcttcggtc agaccgacct cttccagcgc acgggtatca actttaccgt caacggtttc
     2161 agcacgtttg taatgacgca tcgccagcat acgtttcagt gcgcgcagta ccggtttggt
     2221 atcaccggcg gtcagcagat tcgccagata ctgtaccgga atacgcaggc tttcgacgtc
     2281 tggcagaatg ccgttgctac ccagctcacc cgcgtctgct gcagactgaa tcggagacag
     2341 aggcggcacg taccagacca tcggcagtgt gcgatattcc ggatgcagcg gcagcgccag
     2401 tttccattcc attgccattt tataaaccgg cgactgctgt gcggcttcaa taacgctcag
     2461 cggaataccg tctttaatcg cctgctcgat gactttcgga tcgttcggat cgaggaacac
     2521 gtccagctga cgctggtaaa gatctttctc gttctcggtg ctggctgcac gttcaatagc
     2581 gtcggcatcg tacaacagca cgccaagata acggatacga ccgacacagg tttctgagca
     2641 cacggtcggc tgacccgctt caatacgcgg atagcagaag atgcacttct cagacttacc
     2701 gctcttccag ttgaagtaga tttttttgta cgggcatcca gtgatgcaca tacgccagcc
     2761 acggcattta tcctggtcga tcaggacgat gccatcttct tcacgcttgt aaatcgcacc
     2821 gctcgggcag gtcgccacac atgccgggtt caggcagtgt tcgcacaggc gcggcaaata
     2881 catcatgaag gtgttttcga actggctata catcgccttc tggatgttgt cgaagttctt
     2941 gtctttcgcc agtttgtcaa actcaccgcc caggtcatct tcccagttcg gccctttttc
     3001 gattttcgcc atccgttccc cggtaatcag cgaacgcgga cgggcaatcg gctgcgattt
     3061 gctgccttcc ggcgcggtat gcaggttctg atagtcaaaa tcgaacggct cgtaataatc
     3121 gtcgatcccc ggcagatgcg ggttagcgaa gattttaccc agcagcatgg cacggttacc
     3181 catgcgcggc tgcagtttgc cgttgatttt acggatccag ccgcctttgt atttttcctg
     3241 gttttcccag tcagtcggga agccctggcc cggcttggtt tccacgttgt tgaaccacgc
     3301 atattccacg ccttcacggc tggtccagac gtttttacag gtaactgaac aggtgtggca
     3361 gccgatgcac ttatcgagat tcagcaccat gccgacttgt gaacgaattt tcattttacg
     3421 ctctcctgta cctggtcatt gccttcgcca tctaaccagt caatgttctt catcttacgc
     3481 actacaacaa actcatcgcg gttagaacct acggtgccat agtagttaaa gccgtatgcc
     3541 agatgggcat agccgccgat catatgcgtc ggtttcggcg tgatacgggt gaccgagtta
     3601 tggataccac cacgctgttg ggtaatttcc gaaccaggca ggttaacgat acgttcctgc
     3661 gcgtggtaca tcatggtcat ccctgccgga acacgctggc tgacaaccgc acgggcagtc
     3721 agagcaccgt tgctgttgaa gacttcaatc cagtcgttat cggcgatacc cagatctttg
     3781 gcatcggctt cactcaacca gaccaccgga ccaccgcgac ctaaagtcag catcagcagg
     3841 ttgtcgctgt aggtggagtg gataccccac ttctggtgcg gcgtcaggaa gttgagcgct
     3901 ttttcctggt tgccgttgga tttctggcct atcacttctt tcaccgaacg ggtgtcgatc
     3961 ggcggacgat aaaccagcag gctttcaccg aaatcacgca tccactggtg atcctgatac
     4021 agttgctgac gaccagagag cgtacgccat gggatcagct cgtgaacgtt ggtgtaaccg
     4081 gcgttgtaag aaacgtgttc atcttccaga ccagaccagg tcgggctgga gataattttg
     4141 cgcggctgtg cctgaatatc gcggaagcgg atcttctcgt cttctttatt cagcgccaga
     4201 tgcgtatggt cacgaccggt aaattcgctc agggcagccc aggctttcac ggctacctga
     4261 ccgttggttt ccggtgccag tgtcaggatc atctctgccg catcaattgc ggtgttcagc
     4321 atcggctggc ctttcgccgg accttccgct ttggtgtagt tgagcttacg cagcagatcc
     4381 atctcgctct gggtgttcca ggcaatccct ttaccgccat taccgatttt ctccatcagc
     4441 gggccgatag aggtaaagcg ttcgtaagtc gccggataat cgcgctctac gaccataatg
     4501 tgtggcgcgg ttttacctgg gatcaggtcg cactcgcctt ttttccagtc tttcacatcc
     4561 agcggctgcg ccagttcagc ggcagagtca tgctggatag gcagcgtgac gatgtcggtt
     4621 tctttaccca gatggccgac gcacacttcg gagaatttct tcgcgatggc tttgtagatt
     4681 tcccagtcgc ttttcgcttc ccaggccgga tcgaccgccg cagacagcgg gtgaataaac
     4741 ggatgcatat ccgaagtatt catgtcgtct ttttcgtacc aggtcgccgt cggcaaaatg
     4801 atgtcggaat agagacaggt gctcgacaga cggaagtcca gcgtaaccac cagatccagc
     4861 ttgccttcca gaccattgtc ctgccagtcc acttcttccg gcttcacgcc gccctgttgc
     4921 cccagatctt taccctggat accgtgctcc gtccccagca ggtacttgag cataaactca
     4981 tgacctttac cggaagaacc gagcaggtta gaacgccaga tgaacaggtt gcgcgggtgg
     5041 tttttaccgt tttctggttg ttctgccgca aaacggatgg aaccctcttt cagggatttc
     5101 accgtatagt ccaccggatt catcccggct ttttccgctt cgccagcgat agtcagcggg
     5161 ttagtgccta actgcggtgc agacggcagc cagcccatgc gttccgcacg gacgttaaag
     5221 tcgatcaagt gtccggtata gcgggatttg tccgccatcg gtgacagcaa ctcttccgcc
     5281 gtgacggttt cataacgcca ctggctggag tggttataga aataagaagt gctgttcatg
     5341 tgacgcgccg gacgctgcca gtcaagggca aacgccagcg gctgccagcc ggtttgcgga
     5401 cgcagttttt cctgacctac atagtgcgcc cagccgcccc cgctctgacc gacacagccg
     5461 cagaaaatca gcatgttgat cagaccacga tagttcatat cgaggtgata ccagtggttc
     5521 agccccgcac cgacgataat catcgaacga ccgtgcgttt tatcagcgtt atcggcaaat
     5581 tcacgggcga tgcgaataat ctggctgcga gaaacgccgg taatctgctc ggcccaggcc
     5641 ggggtataag ctttcacatc gtcatagctg gttgcacagt taacgtcgtt caggccacgt
     5701 tccagaccgt agtttgccag cgtcagatca taaacggtgg tcaccagggc ggtgctgcca
     5761 tcagccagtt gcaggcgttt caccggcagt ttgtgcagca gcacgttttc cagttccact
     5821 ttgttgaagt gttccgtgcc gtcgccacca aagtacggga agcctacctc agcgatctca
     5881 tcctggctac ccagcaggct cagttgcagc tcggtttctt cgccagtttt gccgtcgcgc
     5941 tgctcaagat tccatttgcc cttctcgccc cagcggaagc caatagaacc gttcggcgca
     6001 accatttcgc cattggtatt aaaggcgaca gttttccatt ccggattgtt ttcctggccc
     6061 agcgcatcaa ccagatcagc agcgcgcagc atacgacctg cagcgtagta accgtcgcgt
     6121 tcttccagca tcaccagcat cggcatgtcg gtgtagcgac gcacatagtc ggtgaaatac
     6181 tggcttgggt tgtcgaggtg gaattcacgc agcattacgt ggcccatcgc cagcgccatt
     6241 gccgcatcgg tgccctgttt cggtgccagc cacagatcgc acagtttggc gatttcagcg
     6301 tagtctggtg tgacggcaac agttttggtc cctttgtaac gcacttcagt aaagaagtga
     6361 gcatccgggg tacgcgtctg cggcacgttt gacccccagg cgatgatgta gctggagttg
     6421 taccagtcag cagattccgg tacgtcagtt tgctcgcccc aggtttgcgg agacgcagga
     6481 ggcaagtcgc agtaccagtc gtagaagctt aagcaagtac cgccaatcag cgagagatag
     6541 cgtgcacccg atgcgtaaga aaccatcgac attgccggaa ttggcgagaa accagcaaca
     6601 cggtccgggc cgtagttttt gatggtgtaa acgttagatg cgacgatcag ttcgttcacc
     6661 tcctgccagg aagaacgaac aaatccaccg cgtccacgcg cctgcttaaa gcttttcgct
     6721 ttatcggcgt cttcaatgat agaagcccat gcctcaaccg gatcgctatg cagcgccttc
     6781 gcttcacgcc acattttcat caggcgtttg cgcatcatcg ggtatttcag gcggttggca
     6841 ctgtaaagat accaggagta gctggcaccg cgcgggcagc cgcgaggttc atggtttggc
     6901 agatccggac gggtacgcgg atagtcagtc tgctgggttt cccaggtgac cagaccgttt
     6961 ttgacgtaga ttttccagct gcaggagccg gtgcagttta ccccgtgggt agagcggacg
     7021 attttgtcat gctgccaacg ctggcgatat ccatcctccc agtcacggtt ggtattgaga
     7081 agctggccat gcccatcggc aaaggtttca cccttctgtt tgaagtagcg aaaccggtcc
     7141 aggaatttac tcatcggttt tctcctgtgg gagcctgtcg gccctctgat aaatcgacat
     7201 tgctaatgtt taagggcaag gtaacgctct gaaacagcgt gggaattgat aacgatcaag
     7261 agtgatgggg atgaaaaata aagtaaattc ctaagatacc cctttaggat aattaacagc
     7321 caccacataa cagactgtaa attaagac
//
LOCUS       DAPOAV010000143         7286 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.144, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000143 DAPOAV010000000
VERSION     DAPOAV010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7286
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.144"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(4..483)
                     /gene="folK"
                     /locus_tag="RN951_004117"
     CDS             complement(4..483)
                     /gene="folK"
                     /locus_tag="RN951_004117"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HDX2529033.1"
                     /translation="MTVAYIAIGSNLASPLEQVNAALKALGDIPESHILTVSSFYRTP
                     PLGPQDQPDYLNAAVALETSLAPEELLNHTQRIELQQGRVRKAERWGPRTLDLDIMLF
                     GNEVINTERLTVPHYDMKNRGFMLWPLFEIAPELVFPDGEMLRQILHTRAFDKLNKW"
     gene            complement(480..1898)
                     /gene="pcnB"
                     /locus_tag="RN951_004118"
     CDS             complement(480..1898)
                     /gene="pcnB"
                     /locus_tag="RN951_004118"
                     /EC_number="2.7.7.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="HDX2529034.1"
                     /translation="MTLPRCTIFTRVANFCRKVLSREESEAEQAVARPQVTVIPREQH
                     AISRKDISENALKVMYRLNKAGYEAWLVGGGVRDLLLGKKPKDFDVTTNATPEQVRKL
                     FRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGNVSDRTTSQRGQNGMLLRDNIFGS
                     IEEDAQRRDFTINSLYYSVADFTVRDYVGGMKDLKDGVIRLIGNPETRYREDPVRMLR
                     AVRFAAKLGMRISPETAEPIPRLATLLNDIPPARLFEESLKLLQAGYGYETYKLLCEY
                     HLFQPLFPTITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLL
                     ETAQKIAQESGLTYHDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQG
                     KRAWKLLEHPKFRAAYDLLALRAEVERNAELQRLVKWWGEFQVSAPPDQKGMLNELDE
                     EPSPRRRTRRPRKRAPRREGTA"
     gene            complement(1937..2863)
                     /gene="gluQRS"
                     /locus_tag="RN951_004119"
     CDS             complement(1937..2863)
                     /gene="gluQRS"
                     /locus_tag="RN951_004119"
                     /EC_number="6.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001432381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA glutamyl-Q(34) synthetase GluQRS"
                     /protein_id="HDX2529035.1"
                     /translation="MLPPYFLFKEMTDTQYIGRFAPSPSGELHFGSLIAALGSYLQAR
                     ARQGRWLVRIEDIDPPREVPGAAETILRQLEHYGLHWDGDVLWQSQRHDAYREALAWL
                     HEQGLSYYCTCTRARIQSIGGIYDGHCRVLHHGPDNAAVRIRQQHPVTQFTDQLRGII
                     HADEKLAREDFIIHRRDGLFAYNLAVVVDDHFQGVTEIVRGADLIEPTVRQISLYQLF
                     GWKVPDYIHLPLALNPQGAKLSKQNHAPALPKGDPRPVLIAALQFLGQQAEAHWQDFS
                     VEQILQSAVKNWRLTAVPESAIVNSTFSNASC"
     gene            complement(2900..3355)
                     /gene="dksA"
                     /locus_tag="RN951_004120"
     CDS             complement(2900..3355)
                     /gene="dksA"
                     /locus_tag="RN951_004120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002209354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-binding protein DksA"
                     /protein_id="HDX2529036.1"
                     /translation="MQEGQNRKTSSLSILAIAGVEPYQEKPGEEYMNEAQLAHFRRIL
                     EAWRNQLRDEVDRTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKT
                     LKKVEDEDFGYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG"
     gene            complement(3533..4237)
                     /gene="sfsA"
                     /locus_tag="RN951_004121"
     CDS             complement(3533..4237)
                     /gene="sfsA"
                     /locus_tag="RN951_004121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HDX2529037.1"
                     /translation="MEFSPPLQRATLIQRYKRFLTDVITPDGRELTLHCPNTGAMTGC
                     ATPGDTVWYSTSDNTKRKYPHTWELTQSQSGAFICVNTLWANRLTKEAILNESISELS
                     GYSSLKSEVKYGAERSRIDFMLQADSRPDCYIEVKSVTLAENEQGYFPDAVTERGQKH
                     LRELMSVAAEGQRAVIFFAVLHSAITRFSPARHIDEKYAQLLSEAQQRGVEILAYKAE
                     ISAEGMALKKSLPVTL"
     gene            complement(4252..4782)
                     /gene="thpR"
                     /locus_tag="RN951_004122"
     CDS             complement(4252..4782)
                     /gene="thpR"
                     /locus_tag="RN951_004122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414689.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2',3'-cyclic phosphodiesterase"
                     /protein_id="HDX2529038.1"
                     /translation="MSEPQRLFFAIDLPAEIREQIIHWRATHFPPEAGRPVAADNLHL
                     TLAFLGEVSAEKEKALSLLAGRIRQPGFTLTLDDAGQWLRSRVVWLGMRQPPRGLIQL
                     ANMLRSQAARSGCFQSNRPFHPHITLLRDASEAVTIPPPGFNWSYAVTEFTLYASSFA
                     RGRTRYTPLKRWALTQ"
     gene            4856..7285
                     /gene="hrpB"
                     /locus_tag="RN951_004123"
     CDS             4856..7285
                     /gene="hrpB"
                     /locus_tag="RN951_004123"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414690.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase HrpB"
                     /protein_id="HDX2529039.1"
                     /translation="MSSLPVAAVLPELLTALDCAPQVLLSAPTGAGKSTWLPLQLLAH
                     PGINGKIILLEPRRLAARNVAQRLAELLNEKPGDTVGYRMRAQNCVGPNTRLEVVTEG
                     VLTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQGLRDDLKLLIMSATLD
                     NDRLQQMLPEAPVVISEGRSFPVERRYLPLPAHQRFDDAVAVATAEMLRQESGSLLLF
                     LPGVGEIQRVQEQLASRIGSDVLLCPLYGALSLNDQRKAILPAPQGMRKVVLATNIAE
                     TSLTIEGIRLVVDCAQERVARFDPRTGLTRLITQRVSQASMTQRAGRAGRLEPGISLH
                     LIAKEQAERAAAQSEPEILQSDLSGLLMELLQWGCSDPAQMSWLDQPPVVNLLAAKRL
                     LQMLGALEGERLSAQGQKMAALGNDPRLAAMLVSAKNDDEAATAAKIAAILEEPPRMG
                     NSDLGVAFSRNQPAWQQRSQQLLKRLNVRGGEADSSLIAPLLAGAFADRIARRRGQDG
                     RYQLANGMGAMLDANDALSRHEWLIAPLLLQGSASPDARILLALLVDIDELVQRCPQL
                     VQQSDTVEWDDAQGTLKAWRRLQIGQLTVKVQPLAKPSEDELHQAMLNGIRDKGLSVL
                     NWTAEAEQLRLRLLCAAKWLPEYDWPAVDDESLLAALETWLLPHMTGVHSLRGLKSLD
                     IYQALRGLLDWGMQQRLDSELPAHYTVPTGSRIAIRYHEDNPPALAVRMQEMFGEATN
                     PTIAQGRVPLVLELLSPAQRPLQITRDLSAFWKGAYREVQKEMKGRYPKHVWPDDPAN
                     TAPTRRTKKYS"
BASE COUNT         1655 a         1896 c         2043 g         1692 t
ORIGIN      
        1 aaattaccat ttgtttaatt tgtcaaatgc tcttgtatgt aagatttgac gcaacatctc
       61 cccatcagga aacaccaact ccggcgcgat ttcaaacagc ggccacagca taaatccacg
      121 attcttcata tcgtagtgcg gaacggtcag gcgttcagta tttatcactt cattaccaaa
      181 cagcatgatg tcgagatcca gcgtgcgtgg tccccagcgt tcagctttgc ggacgcgacc
      241 ttgctgcaat tcaatacgct gtgtgtgatt gagtagctct tcaggtgcaa gagaggtttc
      301 cagcgccacg gctgcgttta agtaatcggg ttgatcttgc ggccccagcg gtggggtgcg
      361 gtaaaacgaa gaaacggtaa gaatgtggct ttcagggata tcgcctaatg ctttcagggc
      421 agcattgacc tgctccagcg gagaggccag attgctgcct atggcaatat acgccactgt
      481 catgcggtac cctcacgacg tggtgcgcgt ttgcgtggac gacgagtacg acgacgcggt
      541 gacggttctt catccagctc gttgagcatc cctttttggt ctggtggcgc ggaaacctgg
      601 aactcacccc accatttcac cagacgctgc agttcagcgt tacgctcaac ttcagctcgc
      661 aaggccaaca ggtcataagc cgcacggaac ttaggatgct ccagcagttt ccatgcgcgt
      721 ttaccctgac gacgggacat acgcaactgc aactgccaga tatcgcgggt taatgtcgtc
      781 agacgtttcg ggattgccag tgaacggcag gcttcgtcca gcacgtcgtt catcgccagc
      841 gcgaaagcgt cgtgataggt caggccgctt tcctgggcga tcttctgtgc cgtctccagc
      901 agtgggtacc agaacatggc ggcaaacagg aacgccgggt tcacgcgcat atcgttatgg
      961 atacgcgtat cggtattctt cagcacctgt tcaatgatcc gctccatcgg gctgtcgcca
     1021 ttttccgtga agtagcgggt aatggtcggg aacagcggct ggaacagatg atattcacac
     1081 aacagcttat aggtttcgta accgtagccc gcttgtagca gtttaagcga ttcttcaaac
     1141 aggcgtgccg gtgggatatc gttcagcagg gtagcgaggc gagggatcgg ttctgcggtt
     1201 tccgggctga tgcgcatacc caatttggcg gcaaaacgta ccgcgcgcag catacgtacc
     1261 ggatcttcac ggtagcgcgt ttccgggtta ccaatcagac ggataacgcc gtccttcaga
     1321 tccttcatgc cgccaacgta atcacggacg gtaaaatccg ctacgctgta atacaggctg
     1381 ttgatagtga aatcgcggcg ctgggcgtct tcttcgatgg agccgaaaat gttgtcgcgc
     1441 agcaacatgc cgttttgccc gcgttgggag gtcgtgcggt cgctgacgtt accttcgtgg
     1501 tgtccacgga aggtcgcaac ttcgataatc tccgggccaa acattacatg agccagacgg
     1561 aaacggcgac ccaccaggcg gcagttacgg aacagtttgc gcacctgctc aggcgtggcg
     1621 ttagtggtta cgtcaaaatc tttcggcttt ttgccaagta acaggtcgcg cacgccgccg
     1681 ccaaccagcc aggcttcgta tcccgcttta ttgagcctgt acattacctt cagggcattt
     1741 tcactgatat ctttgcggga aatagcatgc tgctcacgcg ggatcaccgt cacctgtgga
     1801 cgggcgactg cctgttcagc ctcgctttcc tcgcggctta gcaccttgcg gcaaaaatta
     1861 gcgactcggg taaaaatagt acacctcggt agtgtcaaac atcattcagg acaaaaaaat
     1921 agcggctaat catagctcag catgacgcat ttgagaatgt tgaatttaca attgccgact
     1981 cgggcacggc ggtaagccgc cagtttttga cggctgactg aaggatttgc tcgacgctga
     2041 aatcctgcca gtgtgcttct gcctgctgcc ccagaaattg aagtgccgcg attagtaccg
     2101 ggcgtggatc gcctttcggc aacgcaggcg catgattctg cttggaaagt ttagcgcctt
     2161 gtggattaag cgccagcggc agatgaatgt aatctggcac tttccagcca aaaagctggt
     2221 acagcgagat ttgccttact gttggttcaa tcagatcagc cccacgcact atttctgtaa
     2281 cgccctggaa atgatcatca accacaacag ccaggttgta ggcgaacaac ccatcacggc
     2341 gatgaatgat aaaatcttcc cgtgccagtt tttcgtcggc gtgaataatg ccgcgcagct
     2401 ggtcagtaaa ttgcgtgacc ggatgctgct ggcggatacg cactgcggcg ttgtctggtc
     2461 catgatgcaa cacccggcaa tgaccgtcgt aaataccgcc aatgctttga atacgcgcac
     2521 gcgtacaggt gcagtaataa cttagtcctt gttcatgtaa ccaggcgagt gcttcacgat
     2581 aggcgtcgtg acgttgcgat tgccagagaa catcgccgtc ccagtgcaga ccgtaatgtt
     2641 ccagctggcg caggatagtt tctgcggcac cgggaacttc acgaggcggg tcgatatctt
     2701 ctatgcgtac cagccagcga ccttgccggg cgcgagcctg caaatagctg ccgagcgcgg
     2761 cgatcagaga gccaaaatga agctcgccgg aaggagaggg ggcgaagcgg ccaatatact
     2821 gtgtgtctgt catctctttg aacaaaaaat aaggcgggag catttcccgc ctgtggtaaa
     2881 cgtgatggaa cggctgtaat tagccagcca tctgtttttc gcgaatttca gccagcgttt
     2941 tgcagtcgat gcacagatcg gctgtcgggc gcgcttccag acggcgaata ccaatttcaa
     3001 caccgcagga ttcgcagtag ccgaaatctt cgtcttccac ttttttcagc gtcttctcga
     3061 tctttttgat cagcttacgc tcgcgatcgc ggttacgcag ttcgaggctg aactcttctt
     3121 cctgggctgc acggtctacc gggtccggga agttggctgc ttcatcctgc atatgtgtaa
     3181 cggtgcgatc gacttcatcc ctgagttgat tacgccatgc ttccagaata cgacggaagt
     3241 gcgccagctg ggcttcattc atatactctt cgcccggctt ctcctgatat ggttccaccc
     3301 cagcgatggc gagaatactc agggacgatg ttttacggtt ttgcccttct tgcatgttgc
     3361 ttctccttaa cacgcactat cgatccccat gttcggggga aaaatgaggc cgctataaat
     3421 agcagatgct tttccggata gcaattatct aaacgtaaca cttgacaact gtgtgaggaa
     3481 aagcgtattt gcgcacgcga ccagaatgta aattaaccag ttacttactt tactacaatg
     3541 taaccggcag tgatttttta agagccatgc cttcagcaga aatttccgct ttgtaagcca
     3601 gaatttctac ccccctctgt tgagcttctg acaatagttg cgcgtatttc tcatcgatgt
     3661 ggcgcgcggg tgaaaaccgt gtaatggctg aatgcagcac ggcgaaaaag ataaccgcac
     3721 gctggccttc agccgctacg ctcatcaact cccgaaggtg tttctgacct cgttcagtga
     3781 ccgcatcggg aaaatatccc tgttcgttct ccgctaacgt aaccgatttc acttcaatat
     3841 agcagtctgg acgcgaatcc gcctgcaaca taaagtcaat acggctgcgt tctgcgccgt
     3901 attttacttc gcttttcagc gagctatagc ctgacagttc tgaaattgat tcattaagga
     3961 tagcctcttt cgtcaacctg ttagcccaaa gcgtgttgac gcaaataaat gcgccgctct
     4021 ggctttgagt taattcccag gtgtgtgggt atttccgttt ggtgttgtct gaagtcgaat
     4081 accagacggt atcgccaggc gttgcacaac cggtcatcgc acccgtattc gggcagtgta
     4141 gcgttaattc gcgaccatcg ggtgtgatca catcggttaa aaaacgtttg taacgctgaa
     4201 ttagcgtcgc gcgctgtaga gggggagaaa attccattgc gacaatcctt gttattgcgt
     4261 tagcgcccag cgttttagcg gcgtgtagcg tgtgcgtcca cgggcaaacg aggaggcgta
     4321 aagggtgaac tccgtcaccg catacgacca gttaaaacct ggcggcggga ttgtcaccgc
     4381 ctcgctggcg tcgcgcaata aggtaatatg tggatgaaac ggacgattgc tttgaaaaca
     4441 accgctgcgg gcagcctgtg aacggagcat attcgccagc tggattaagc cgcgtggcgg
     4501 ctgacgcatc cctaaccaca ccacacgcga acgcagccat tgtccggcgt catcaagcgt
     4561 gagtgtgaaa ccaggttgac gaatccgtcc ggctaaaaga gaaagcgcct tctctttctc
     4621 ggcgctcact tcgcctaaaa atgccagagt cagatgcaaa ttatcggcgg cgaccggacg
     4681 tcccgcctca ggtgggaagt gtgtggcgcg ccaatggata atctgttcgc ggatttctgc
     4741 aggtaagtcg atagcaaaga acagacgttg cggttcagac atgtgaggca ctcggttatg
     4801 aattaccgcg atgctacaat gtggcgcgaa gaatgttaac cctctggagc gttttgtgtc
     4861 gtcgttgccc gttgctgccg tcttacctga attacttacc gctctcgatt gtgcgccgca
     4921 ggtattatta agtgcgccga ccggggccgg gaaatcaacc tggctgccgc tgcaactgct
     4981 ggcgcatccc ggcattaacg ggaaaattat cctgctggag ccgcgtcgtc tggcggcgcg
     5041 taacgtcgcg caacggctgg cggagctgct taacgaaaag ccaggcgata ccgttggcta
     5101 ccggatgcgt gcgcaaaact gcgtcgggcc gaatacccgc ctggaagtgg ttaccgaagg
     5161 cgtgctgacg cgcatgatcc agcgtgaccc ggaactgagc ggtgttggac tggtgatcct
     5221 tgatgaattt catgagcgca gcttgcaggc ggatttggcg ttggcgctgt tactcgatgt
     5281 gcaacaaggt ctgcgtgatg accttaaact gctgattatg tcggctaccc tggacaacga
     5341 ccgcttgcag caaatgctgc cagaagcgcc tgtcgtcatc tcagaagggc gctcgtttcc
     5401 ggttgaacgc cgttatttac cgctgcccgc gcatcagcgt tttgacgatg ccgttgcggt
     5461 agccaccgct gaaatgctgc gtcaggaaag cggatcatta ctgttatttt tacctggcgt
     5521 cggagaaatt cagcgtgtgc aggaacaact ggcttcgcgc atcggcagtg atgtattgct
     5581 ctgcccgctg tatggcgcgt tgtcgctgaa cgatcagcga aaagcgatcc tcccggcacc
     5641 gcaagggatg cgcaaagtgg tgctggcgac caatattgct gaaaccagtt taaccattga
     5701 aggtattcgt ctggtggtgg attgtgccca ggagcgtgtg gcgcgttttg atccgcgcac
     5761 ggggcttacg cgactgatta ctcaacgcgt tagccaggca tccatgacgc agcgtgccgg
     5821 gcgcgccggg cgtctggagc cgggtatcag cctgcattta atcgccaaag aacaagcaga
     5881 acgcgccgcg gcgcaaagtg aaccggagat cttacaaagc gatctttccg gtttgctgat
     5941 ggaattactg caatggggat gcagcgatcc ggcgcagatg agctggctgg atcaaccgcc
     6001 agtagtgaat ctactggccg cgaaacgtct gttacaaatg ctgggggcac tggagggtga
     6061 acggcttagt gcgcaagggc aaaaaatggc agcgctgggt aacgatccgc gtttagcggc
     6121 aatgctggtt agcgcgaaga acgacgacga agctgctacc gcggcaaaaa ttgccgccat
     6181 tctcgaagag ccgccacgga tgggcaatag tgacctgggc gtggcgtttt cgcgcaatca
     6241 accagcctgg cagcaacgta gtcagcaact gttaaaacgc ttaaacgtac gtggcggtga
     6301 ggcagacagt tcgcttatcg cgccgctact tgccggggcg tttgccgatc gcattgctcg
     6361 tcgccgtggg caagatggac gctatcaact ggcaaacggc atgggagcga tgctcgatgc
     6421 caacgacgcg ctaagccgcc acgaatggtt gatcgcaccg ttattattgc agggcagcgc
     6481 ctcgccggat gcgcggattt tactggcgct gctggtcgat attgatgagt tagtacaacg
     6541 ctgcccgcag ctggtacagc agtctgacac tgtggagtgg gatgacgcgc aaggtacgct
     6601 gaaagcctgg cgtcggctac aaatcggtca gttgacggtg aaagtgcagc cgctggcgaa
     6661 accgtcagaa gacgagttgc atcaggcgat gcttaatggc atccgtgata aaggtttaag
     6721 cgtgctcaac tggacggcgg aagcggaaca gctacgcttg cgtttgttat gcgccgcaaa
     6781 gtggttgccg gaatatgact ggccagcggt tgatgatgaa agtttattgg cagcgctgga
     6841 aacgtggctg ctgccacata tgactggcgt acattcacta cgcggcctga aatcactcga
     6901 catttatcag gcactacgcg gattacttga ttggggaatg cagcaacgtc tggatagtga
     6961 attgcctgcg cattacactg tgccgacggg aagccggatc gccattcgtt atcatgaaga
     7021 taacccgccc gcgctggcgg tgagaatgca agagatgttt ggcgaggcca ccaatccgac
     7081 gatcgcccag gggcgcgtgc cgctggtgct ggagttgctt tcacctgccc aaaggccatt
     7141 acaaatcaca cgagatttga gcgccttctg gaaaggagcg taccgtgagg tgcaaaaaga
     7201 gatgaaaggg cgttatccca aacatgtctg gccggacgac ccggcaaata ctgcaccgac
     7261 gcgacggacg aaaaagtatt cgtaag
//
LOCUS       DAPOAV010000144         7233 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.145, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000144 DAPOAV010000000
VERSION     DAPOAV010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7233
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.145"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..804
                     /gene="yneK"
                     /locus_tag="RN951_004124"
     CDS             <1..804
                     /gene="yneK"
                     /locus_tag="RN951_004124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative protein YneK"
                     /protein_id="HDX2529040.1"
                     /translation="QVVINLSPIYLDNFRHDGEINIFCAPNPKPVTMGRVFQTGVERV
                     LFLFLNDFIEQFPMINPGVPIKRAHTPHIEPLPSDHHTAADYLRQFDLLVLNFISRGN
                     FVILPRLWNNSEVHRWFVNKDPNLITAILDITDSELKEDLLQSLMDSLGSNKHVLPEV
                     CICFLSLLAEQESPHFQNLFLFFANMLLHYHQFMNPNESDLNDVLMPASLSDDKIIKH
                     MARRTLKLFVKNETPPKVTHEDLVKNRPRSPVRPPIPATAKTPDLPERH"
     gene            954..2144
                     /gene="ydeA"
                     /locus_tag="RN951_004125"
     CDS             954..2144
                     /gene="ydeA"
                     /locus_tag="RN951_004125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose MFS transporter"
                     /protein_id="HDX2529041.1"
                     /translation="MTTNTVSRKVAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAQSFH
                     MQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLSFLSWSFT
                     VLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGLPLGRIV
                     GQYFGWRMTFFAIGIGALITLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSIYLLT
                     VVVVTAHYTAYSYIEPFVQNIAGFSANFATALLLLLGGAGIIGSVIFGKLGNQYASAL
                     VSTAIALLLVCLALLLPAANSEIHLGVLSIFWGIAMMIIGLGMQVKVLALAPDATDVA
                     MALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGAVPAFAALIWSIIIFRRWPVTLE
                     EQTQ"
     gene            complement(2169..2834)
                     /gene="marC"
                     /locus_tag="RN951_004126"
     CDS             complement(2169..2834)
                     /gene="marC"
                     /locus_tag="RN951_004126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter MarC"
                     /protein_id="HDX2529042.1"
                     /translation="MLDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQS
                     LMASVYVFAIMMVAYYAGQLVMDTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAIDSP
                     EAKSKSEELEDEPSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMVAP
                     PLIFFLVAVILWGSLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEIIK
                     TYH"
     gene            3046..3480
                     /gene="marR"
                     /locus_tag="RN951_004127"
     CDS             3046..3480
                     /gene="marR"
                     /locus_tag="RN951_004127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416047.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance transcriptional
                     regulator MarR"
                     /protein_id="HDX2529043.1"
                     /translation="MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFK
                     VLCSIRCAACITPVELKKVLSVDLGALTRMLDRLVCKGWVERLPNPNDKRGVLVKLTT
                     GGAAICEQCHQLVGQDLHQELTKNLTADEVATLEYLLKKVLP"
     gene            3500..3883
                     /gene="marA"
                     /locus_tag="RN951_004128"
     CDS             3500..3883
                     /gene="marA"
                     /locus_tag="RN951_004128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707445.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     MarA"
                     /protein_id="HDX2529044.1"
                     /translation="MSRRNTDAITIHSILDWIEDNLESPLSLEKVSERSGYSKWHLQR
                     MFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYLAERYGFESQQTLTRTFKNYFDV
                     PPHKYRMTNMQGESRFLHPLNHYNS"
     gene            3915..4133
                     /gene="marB"
                     /locus_tag="RN951_004129"
     CDS             3915..4133
                     /gene="marB"
                     /locus_tag="RN951_004129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance protein MarB"
                     /protein_id="HDX2529045.1"
                     /translation="MKPLSSAIAAALILFSAQGVAEQTTQPVVTSCANVVVVPPSQEH
                     PPFDLNHMGTGSDKSDALGVPYYNQHAM"
     gene            complement(4164..5062)
                     /gene="eamA"
                     /locus_tag="RN951_004130"
                     /pseudo
     CDS             complement(4164..5062)
                     /gene="eamA"
                     /locus_tag="RN951_004130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416050.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylserine/cysteine exporter"
     gene            5257..6444
                     /gene="ydeE"
                     /locus_tag="RN951_004131"
     CDS             5257..6444
                     /gene="ydeE"
                     /locus_tag="RN951_004131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux MFS transporter YdeE"
                     /protein_id="HDX2529046.1"
                     /translation="MNLSLRRSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDL
                     IGYAMTIALTIGVVFSLGFGILADKFDKKRYMLLAITAFASGFIAIPLVNNVTLVVLF
                     FALINCAYSVFATVLKAWFADNLSSTSKTKIFSINYTMLNIGWTIGPPLGTLLVMQSI
                     NLPFWLAAICSAFPMLFIQIWVKRSEKIIATETGSVWSPKVLLQDKALLWFTCSGFLA
                     SFVSGAFASCISQYVMVIADGDFAEKVVAVVLPVNAAMVVTLQYSVGRRLNPANIRAL
                     MTAGTLCFVIGLVGFIFSGNSLLLWGMSAAVFTVGEIIYAPGEYMLIDHIAPPEMKAS
                     YFSAQSLGWLGAAINPLVSGVVLTSLPPSSLFVILALVIIAAWVLMLKGIRARPWGQP
                     ALC"
     gene            6571..6666
                     /gene="mgtS"
                     /locus_tag="RN951_004132"
     CDS             6571..6666
                     /gene="mgtS"
                     /locus_tag="RN951_004132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein MgtS"
                     /protein_id="HDX2529047.1"
                     /translation="MLGNMNVFMAVLGIILFSGFLAAYFSHKWDD"
     gene            complement(6885..>7233)
                     /gene="dgcZ"
                     /locus_tag="RN951_004133"
     CDS             complement(6885..>7233)
                     /gene="dgcZ"
                     /locus_tag="RN951_004133"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="diguanylate cyclase DgcZ"
                     /protein_id="HDX2529048.1"
                     /translation="DVVLRTLATYLASWTRDYETVYRYGGEEFIIIVKAANDEEACRA
                     GVRICQLVDNHAITHSEGHINITVTAGVSRAFPEEPLDVVIGRADRAMYEGKQTGRNR
                     CMFIDEQNVINRV"
BASE COUNT         1852 a         1801 c         1641 g         1939 t
ORIGIN      
        1 caggtagtaa taaatttaag ccctatttat ttagataatt ttcgccatga tggagaaatt
       61 aatatttttt gcgctcccaa cccaaagcct gtcactatgg ggcgcgtatt tcagaccggc
      121 gtcgagcgtg tactctttct gtttctgaat gattttattg aacaatttcc aatgatcaac
      181 cctggtgttc ccatcaaaag agcgcataca ccacatattg aacccctgcc ttcggatcac
      241 cataccgctg cagattactt acgccagttt gatttgcttg tcctgaattt tatctctcgc
      301 ggtaattttg tcatactccc ccgattatgg aataactctg aggttcacag atggttcgtc
      361 aataaagatc ctaacttgat caccgccatt ctcgacataa cggacagcga attaaaagag
      421 gatttgttgc aaagcctgat ggattcatta ggttctaaca aacatgtact acccgaagtc
      481 tgcatctgct ttttatccct tttagcagaa caagaatctc ctcattttca gaacttgttt
      541 ttatttttcg ccaatatgtt attgcactat caccaattta tgaatcccaa tgaaagtgat
      601 ttgaatgacg tgttgatgcc agcatcatta agtgatgata aaattatcaa acatatggcg
      661 cgcaggaccc tcaaactgtt tgtaaaaaat gaaacaccgc caaaagttac tcacgaagac
      721 ctggtgaaaa acaggcctcg ctcccctgtc agaccaccta tacccgcaac cgccaaaacg
      781 ccagacctcc ctgaacgtca ttaaaccgtg atgttaccga ctctctgacg cgtgaaagaa
      841 tcagcgtcag agaaacggaa aacgcgatcc agatcacaaa tgcattgtat tcacatcatt
      901 aaccgtttta agatcatttc atcacttttt cgcaactcac ccgataatct gttatgacaa
      961 caaacactgt ttcccgcaaa gtggcgtggc tacgggtcgt tacgctggca gtcgccgcct
     1021 tcatcttcaa caccaccgaa tttgtccctg ttggcctgct ctctgacatt gcgcaaagtt
     1081 ttcacatgca aaccgctcag gtcggcatca tgttgaccat ttacgcatgg gtagtagcgc
     1141 taatgtcatt gccttttatg ttaatgacca gtcaggttga acggcgcaaa ttactgatct
     1201 gcctgtttgt ggtgtttatt gccagccacg tactgtcgtt tttgtcgtgg agctttaccg
     1261 ttctggtgat cagtcgcatt ggtgtggctt ttgcacatgc gattttctgg tcgattacgg
     1321 cgtctctggc gatccgtatg gctccggccg ggaagcgagc acaggcattg agtttaattg
     1381 ccaccggtac agcactggcg atggtcttag gtttacctct cgggcgcatt gtgggccagt
     1441 atttcggttg gcgaatgacc ttcttcgcga ttggtattgg ggcgcttatc acccttttgt
     1501 gcctgattaa gttacttccc ttactgccca gtgagcattc cggttcactg aaaagcctcc
     1561 cgctattgtt ccgccgcccg gcattgatga gcatttattt gttaactgtg gtggttgtca
     1621 ccgcccatta cacggcatac agctatatcg agccttttgt acaaaacatt gcgggattca
     1681 gcgccaactt tgccacggca ttactgttat tactcggtgg tgcgggcatt attggcagcg
     1741 tgattttcgg taaactgggt aatcagtatg cgtctgcgtt ggtgagtacg gcgattgcgc
     1801 tgttgctggt gtgcctggca ttgctgttac ctgcggcgaa cagtgaaata cacctcgggg
     1861 tgctgagtat tttctggggg atcgcgatga tgatcatcgg gcttggtatg caggttaaag
     1921 tgctggcgct ggcaccagat gctaccgacg tcgcgatggc gctattctcc ggcatattta
     1981 atattggaat cggggcgggt gcgttggtag gtaatcaggt gagtttgcac tggtcaatgt
     2041 cgatgattgg ttatgtgggc gcggtgcctg cttttgccgc gttaatttgg tcaatcatta
     2101 tatttcgccg ctggccagtg acactcgaag aacagacgca atagttgaaa ggcccattcg
     2161 ggcctttttt aatggtacgt tttaatgatt tccaggatgc cgttaataat aaactgcaca
     2221 cccatacata ccagcaggaa tcccatcaga cgggagatcg cttcaatgcc acccttgccc
     2281 accagccgca taattgcgcc ggagctgcgt aggcttcccc acaaaataac cgccaccagg
     2341 aaaaagatca gcggcggcgc aaccatcagt acccaatcag cgaaggttga actctgacgc
     2401 actgtggacg ccgagctaat aatcatcgct atggttcccg gaccggcagt acttggcatt
     2461 gccagcggca caaaggcaat attggcactg ggttcatctt ccagctcttc cgacttgctt
     2521 ttcgcctccg gtgaatcaat cgctttctgt tgcggaaaga gcatccgaaa accgataaac
     2581 gcgacgatta agccgcctgc aattcgcaga ccgggaatcg aaatgccaaa tgtatccatc
     2641 accagttgcc cggcgtaata cgccaccatc atgatggcaa atacgtacac cgaggccatc
     2701 aacgactgac gattacgttc ggcactgttc atgttgcctg ccaggccaag aaataacgcg
     2761 acagttgtta atgggttagc taacggcagc aacaccacca gccccaggcc aattgcttta
     2821 aacaaatcta acattggtgg ttgttatcct gtgtatctgg gttatcagcg aaaagtataa
     2881 ggggtaaaca aggataaagt gtcactcttt agctagcctt gcatcgcatt gaacaaaact
     2941 tgaaccgatt tagcaaaacg tggcatcggt caattcattc atttgactta tacttgcctg
     3001 ggcaatatta tcccctgcaa ctaattactt gccagggcaa ctaatgtgaa aagtaccagc
     3061 gatctgttca atgaaattat tccattgggt cgcttaatcc atatggttaa tcagaagaaa
     3121 gatcgcctgc ttaacgagta tctgtctccg ctggatatta ccgcggcaca gtttaaggtg
     3181 ctctgctcta tccgctgcgc ggcgtgtatt actccggttg aactgaaaaa ggtattgtcg
     3241 gtcgacctgg gagcactgac ccgtatgctg gatcgcctgg tctgtaaagg ctgggtggaa
     3301 aggttgccga acccgaatga caagcgcggc gtactggtaa aacttaccac cggcggcgcg
     3361 gcaatatgtg aacaatgcca tcaattagtt ggccaggacc tgcaccaaga attaacaaaa
     3421 aacctgacgg cggacgaagt ggcaacactt gagtatttgc ttaagaaagt cctgccgtaa
     3481 acaaaaaaga ggtatgacga tgtccagacg caatactgac gctattacca ttcatagcat
     3541 tttggactgg atcgaggaca acctggaatc gccactgtca ctggagaaag tgtcagagcg
     3601 ttcgggttac tccaaatggc acctgcaacg gatgtttaaa aaagaaaccg gtcattcatt
     3661 aggccaatac atccgcagcc gtaagatgac ggaaatcgcg caaaagctga aggaaagtaa
     3721 cgagccgata ctctatctgg cagaacgata tggcttcgag tcgcaacaaa ctctgacccg
     3781 aaccttcaaa aattactttg atgttccgcc gcataaatac cggatgacca atatgcaggg
     3841 cgaatcgcgc tttttacatc cattaaatca ttacaacagc tagttgaaaa cgtgacaacg
     3901 tcactgaggc aatcatgaaa ccactttcat ccgcaatagc agctgcgctt attctctttt
     3961 ccgcgcaggg cgttgcggaa caaaccacgc agccagttgt tacttcttgt gccaatgtcg
     4021 tggttgttcc cccgtcgcag gaacacccac cgtttgattt aaatcacatg ggtactggca
     4081 gtgataagtc ggatgcgctc ggcgtgccct attataatca acacgctatg tagtttgttc
     4141 tggccccgac atctcggggc ttattaactt cccaccttta ccgctttacg ccaccgcaag
     4201 ccaaatacat tgatatacag cccggtcata atgagcaccg cacctaaaat tgcagacccg
     4261 ttaagcgttc atccaacaat agtgccgcac ttgccagtcc tactacgggc accagtaacg
     4321 ataacggtgc agcccgccag gtttcatagc gtcccagtaa cgtcccccag atcccataac
     4381 caacaattgt cgccacaaac gccagataca tcagagacaa gatggtggtc atatcgatag
     4441 taaccagact gtgaatcatg gttgcggaac catcgagaat cagcgaggca acaaagaagg
     4501 gaatgattgg gattaaagcg ctccagatta ccagcgacat caccgccgga cgcgttgagt
     4561 gcgacatgat ctttttattg aagatgttgc cacacgccca actaaatgct gccgccaggg
     4621 tcaacataaa gccgagcatc gccacatgct gaccgttcag actatcttcg attaacacca
     4681 gtacgccaaa aatcgctaag gcgatccccg ccaattgttt gccatgcagt cgctccccga
     4741 aagtaaacgc gccaagcatg atagtaaaaa acgcctgtgc ctgtaacacc agcgaagcca
     4801 gtccagcagg cataccgaag ttaatggcac aaaaaagaaa agcaaactgc gcaaaactga
     4861 tggttaatcc ataccccagc agcaaattca gtggtacttt cggtcgtgcg acaaaaaaga
     4921 tagccggaaa agcgaccagc ataaagcgca aaccggccag catcagcggt ggcatgttat
     4981 gaagccccac tttgatgacc acaaaattta gcccccatac gaccactacc agtagcgcca
     5041 acaccccatc ttttcgcgac attctaccgc ctctgaattt catcttttgt aagcaatcaa
     5101 cttagctgaa tttacttttc tttaacagtt gattcgttag tcgccggtta cgacggcatt
     5161 aatgcgcaaa taagtcgcta tacttcggat ttttgccatg ctatttcttt acatctctaa
     5221 aacaaaacat aacgaaacgc actgccggac agacaaatga acttatccct acgacgctct
     5281 accagcgccc ttcttgcctc gtcgttgtta ttaaccatcg gacgcggcgc tacgctgcca
     5341 tttatgacca tttacttgag tcgccagtac agcctgagtg tcgatctaat cggttatgcg
     5401 atgacaattg cgctcactat tggcgtcgtt tttagcctcg gttttggtat cctggcggat
     5461 aagttcgaca agaaacgcta tatgttactg gcaattaccg ccttcgccag cggttttatt
     5521 gccattcctt tagtgaataa cgtgacgctg gttgtgctct tttttgccct cattaactgc
     5581 gcctattctg tttttgctac cgtgctgaaa gcctggtttg ccgacaatct ttcgtccacc
     5641 agcaaaacga aaatcttctc aatcaactac accatgctaa acattggctg gaccatcggt
     5701 ccgccgctcg gcacgctgtt ggtgatgcag agcatcaatc tgcccttctg gctggcagct
     5761 atctgttccg cgtttcccat gcttttcatt caaatttggg taaagcgcag cgagaaaatc
     5821 atcgccacgg aaacaggcag tgtctggtcg ccgaaagttt tattacaaga taaagcactg
     5881 ttgtggttta cctgctctgg ttttctggct tcttttgtaa gcggcgcatt tgcttcatgc
     5941 atttcacaat atgtgatggt gattgctgat ggggattttg ccgaaaaggt ggtcgcggtt
     6001 gttcttccgg tgaatgctgc catggtggtt acgttgcaat attccgtggg ccgccgactt
     6061 aacccggcta acatccgcgc gctgatgaca gcaggcaccc tctgtttcgt catcggtctg
     6121 gtcggtttta ttttttccgg caacagcctg ctattgtggg gtatgtcagc tgcggtattt
     6181 actgtcggtg aaatcattta tgcgccgggc gagtatatgt tgattgacca tattgcgccg
     6241 ccagaaatga aagccagcta tttttccgcc cagtctttag gctggcttgg tgccgcgatt
     6301 aacccattag tgagtggcgt agtgctaacc agcctgccgc cttcctcgct gtttgtcatc
     6361 ttagcgttgg tgatcattgc tgcgtgggtg ctgatgttaa aagggattcg agcaagaccg
     6421 tgggggcagc ccgcgctttg ttgatttaag tcgaacacaa taaagattta attcagcctt
     6481 cgtttaggtt acctctgcta atatctttct cattgagatg aaaattaagg taagcgagga
     6541 aacacaccac accataaacg gaggcaaata atgctgggta atatgaatgt ttttatggcc
     6601 gtactgggaa taattttatt ttctggtttt ctggccgcgt atttcagcca caaatgggat
     6661 gactaatgaa cggagataat ccctcaccta accggcccct tgttacagtt gtgtacaagg
     6721 ggcctgattt ttatgacggc gaaaaaaaac cgccagtaaa ccggcggtga atgcttgcat
     6781 ggatagattt gtgttttgct tttacgctaa caggcatttt cctgcactga taacgaatcg
     6841 ttgacacagt agcatcagtt ttctcaatga atgttaaacg gagcttaaac tcggttaatc
     6901 acattttgtt cgtcaataaa catgcagcga tttcttccgg tttgcttacc ctcatacatt
     6961 gcccggtccg ctcttccaat gaccacatcc agaggctctt caggaaatgc gcgactcaca
     7021 cctgctgtca cggtaatgtt gatatgccct tcagaatgtg tgatggcatg gttatcgact
     7081 aactggcaaa ttctgacacc tgcacgacat gcttcttcat cattagccgc tttgacaata
     7141 atgataaatt cttcgccccc gtagcgataa accgtttcgt aatcacgcgt ccaactggct
     7201 aagtaagttg ccagggtgcg taatactaca tcg
//
LOCUS       DAPOAV010000145         7228 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.146, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000145 DAPOAV010000000
VERSION     DAPOAV010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7228
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.146"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..3123
                     /locus_tag="RN951_004134"
     CDS             <1..3123
                     /locus_tag="RN951_004134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001454588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HDX2529049.1"
                     /translation="GTGEATIREGGLVTAENTIIGGNATGIGTLNVQDQDSVITVRRL
                     YNGYFGNGTVNISNNGLINNKEYSLVGVQDGSHGVVNVTDKGHWNFLGTGEAFRYIYI
                     GDAGDGELNVSSEGKVDSGIITAGMKETGTGNITVKDKNSVITNLGTNLGYDGHGEMN
                     ISNQGLVVSNGGSSLGYGETGVGNVSITTGGMWEVNKNVYTTIGVAGVGNLNISDGGK
                     FVSQNITFLGDKASGIGTLNLMDATSSFDTVGINVGNFGSGIVNVSNGATLNSTGYGF
                     IGGNASGKGIVNISTDSLWNLKTSSTNAQLLQVGVLGTGELNITTGGIVKARDTQIAL
                     NDKSKGDVRVDGQNSLLETFNMYVGTSGTGTLTLTNNGTLNVEGGEVYLGVFEPAVGT
                     LNIGAAHGEAAADAGFITNATKVEFGLGEGVFVFNHTNNSDAGYQVDMLITGDDKDGK
                     VIHDAGHTVFNAGNTYSGKTLVNDGLLTIASHTADGVTGMGSSEVTIANPGTLDILAS
                     TNSAGDYTLTNALKGDGLMRVQLSSSDKMFGFTHATGTEFAGVAQLKDSTFTLERDNT
                     AALTHAMLQSDSENTTSVKVGEQSIGGLAMNGGTIIFDTDIPAATLAEGYISVDTLVV
                     GAGDYTWKGRNYQVNGTGDVLIDVPKPWNDPMANNPLTTLNLLEHDDSHVGVQLVKAQ
                     TVIGSGGSLTLRDLQGDEVEADKTLHIAQNGTVVAEGDYGFRLTTAPGNGLYVNYGLK
                     ALNIHGGQKLTLAEHGGAYGATADMSAKIGGEGDLAINTVRQVSLSNGQNDYQGATYV
                     QMGTLRTDADGALGNTRELNISNAAIVDLNGSTQTVETFTGQMGSTVLFKEGALTVNK
                     GGISQGELTGGGNLNVTGGTLAIEGLNARYNALTSISPNAEVSLDNTQGLGRGNIAND
                     GLLTLKNVTGELRNSISGKGIVSATARTDVELDGDNSRFVGQFNIDTGSALSVNEQKN
                     LGDASVINNGLLTISTERSWAMTHSISGSGDVTKLGTGILTLNNDSAAYQGTTDIVGG
                     GNCFRFRLCH"
     gene            3203..4015
                     /locus_tag="RN951_004135"
                     /pseudo
     CDS             3203..4015
                     /locus_tag="RN951_004135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368382.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
     gene            4898..5164
                     /gene="hipB"
                     /locus_tag="RN951_004136"
     CDS             4898..5164
                     /gene="hipB"
                     /locus_tag="RN951_004136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HipB"
                     /protein_id="HDX2529050.1"
                     /translation="MMSFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISN
                     FENNPDNTTLTTFFKILQSLELSMTLCDAKNASPESTEQQNLEW"
     gene            5164..6486
                     /gene="hipA"
                     /locus_tag="RN951_004137"
     CDS             5164..6486
                     /gene="hipA"
                     /locus_tag="RN951_004137"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system serine/threonine
                     protein kinase toxin HipA"
                     /protein_id="HDX2529051.1"
                     /translation="MPKLVTWMNNQRVGELTKLANGAHTFKYAPEWLASRYARPLSLS
                     LPLQRGNITSDAVFNFFDNLLPDSPIVRDRIVKRYHAKSRQPFDLLSEIGRDSVGAVT
                     LIPEDETVTHPIMAWEKLTEARLEEVLTAYKADIPLGMIREENDFRISVAGAQEKTAL
                     LRIGNDWCIPKGITPTTHIIKLPIGEIRQPNATLDLSQSVDNEYYCLLLAKELGLNVP
                     DAEIIKAGNVRALAVERFDRRWNAERTVLLRLPQEDMCQTFGLPSSVKYESDGGPGIA
                     RIMAFLMGSSEALKDRYDFMKFQVFQWLIGATDGHAKNFSVFIQAGGSYRLTPFYDII
                     SAFPVLGGTGIHISDLKLAMGLNASKGKKTAIDKIYPRHFLATAKVLRFPEVQMHEIL
                     SDFARMIPAALDNVKTSLPTDFPENVVTAVESNVLRLHGRLSREYGSK"
     gene            6798..7006
                     /locus_tag="RN951_004138"
                     /pseudo
     CDS             6798..7006
                     /locus_tag="RN951_004138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226947.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
BASE COUNT         1977 a         1570 c         1989 g         1692 t
ORIGIN      
        1 ggaactgggg aggcgactat tcgcgagggg gggttggtta cggctgaaaa tacgattatc
       61 ggtggcaatg ccaccggtat cggaaccctg aatgtgcagg atcaagactc tgtcatcacg
      121 gtacgcagac tctataatgg atatttcggt aatggcacag tcaatatttc caataatgga
      181 ctgattaata acaaagaata ttcattggtg ggcgttcagg acggttccca cggtgtcgtc
      241 aacgtgaccg ataaagggca ttggaatttc ctcggaacgg gcgaagcttt ccgctatatc
      301 tatatcggtg atgctggcga cggtgaactt aatgtctcga gtgaaggcaa agtagattcg
      361 ggaattatca ctgcggggat gaaagaaaca ggcacaggca acattactgt taaggataag
      421 aactccgtta tcactaatct cggaactaat cttggttatg acggccacgg cgaaatgaat
      481 atcagtaatc aggggcttgt tgtcagcaac ggaggaagtt cactcggtta tggagaaacc
      541 ggcgtcggga atgtcagcat caccacgggg ggaatgtggg aggtcaataa gaatgtctat
      601 accaccattg gtgttgcggg cgtcggaaac ctcaatatta gcgatggcgg taagttcgta
      661 tcgcaaaata ttactttttt gggcgataaa gcaagcggta tcggcacact gaacctgatg
      721 gatgcgacat catcgttcga tactgtgggt atcaatgtcg gtaattttgg tagcggtatc
      781 gtaaatgtca gtaatggtgc cacccttaat tcaacgggct atggatttat cggaggaaat
      841 gcctccggta aggggatagt taatatttca acggacagtc tctggaattt aaagacatca
      901 tctactaacg cacaattgct acaggtcggt gtattaggca cgggtgaact gaatattacc
      961 accggaggta tagttaaagc gcgtgataca cagatagctc tcaatgacaa aagtaagggc
     1021 gacgtgaggg tggatgggca gaactctctt cttgaaacat tcaatatgta cgtagggaca
     1081 tctggtacgg gtacgttaac cctgacgaat aacggtacgc tgaatgtcga aggtggagaa
     1141 gtttacttag gtgtttttga gcctgctgta ggaacgctaa acattggtgc tgctcacggt
     1201 gaggcggcgg cagatgccgg atttatcacc aatgcgacga aagtggagtt tggtcttggc
     1261 gaaggcgttt ttgtctttaa tcataccaat aacagtgatg ccggctacca ggtcgatatg
     1321 ctgattacag gtgacgataa agacggaaaa gtgatccatg atgcaggcca tacggtgttc
     1381 aatgcaggga atacttatag cggtaaaacg ctggtcaatg acggcctcct gaccattgcg
     1441 tctcatacgg cagatggggt aacgggcatg gggtcgagtg aagtaaccat tgcaaacccc
     1501 ggtacgctcg acattctcgc atcaacgaac agtgcaggag attacacgct gaccaatgcg
     1561 ctcaaaggcg atggcttgat gcgagtgcag ctgtcatcct ccgacaagat gtttggcttt
     1621 acccatgcaa cagggactga attcgccggt gttgcccaac tgaaagacag taccttcact
     1681 ctggaacgcg acaacaccgc tgcgcttact cacgcgatgt tgcagtctga cagtgaaaat
     1741 accacatcgg taaaagttgg agagcaatcc attggtggac tggccatgaa tggaggtacc
     1801 atcattttcg atacggatat tcctgctgcg acgctcgcgg agggatatat cagcgtcgat
     1861 acgctggttg tcggcgcggg tgactacacc tggaaaggcc gtaactatca ggtaaacggg
     1921 acgggcgacg tgcttatcga cgtgcctaaa ccgtggaatg atcccatggc gaataaccct
     1981 ctgacgacgc tcaatttgct ggaacacgac gatagccatg tcggcgttca actggtgaag
     2041 gcgcaaacgg ttattgggtc gggtggctca ttaacgttac gtgatttaca gggcgacgag
     2101 gtggaagcgg acaaaacgtt acacattgcg caaaacggaa cggtggtcgc cgagggtgat
     2161 tatggattcc gcctcacgac cgcaccaggt aatggtttgt acgttaacta tgggctgaaa
     2221 gcgctgaaca tccatggtgg gcaaaagctg acgttagccg aacatggcgg agcctatggc
     2281 gcaacggccg atatgtcggc aaaaatcggt ggtgaagggg atctggcaat caatacggtg
     2341 cgacaggttt cgctttccaa cggtcagaac gactatcagg gggcaaccta cgttcagatg
     2401 gggacattac gtaccgatgc ggatggtgca cttggcaaca cccgggaact gaacatcagc
     2461 aacgcggcca tcgtcgatct taatggatcg acgcagacgg tagagacatt caccgggcag
     2521 atgggttcga ctgttttgtt caaagagggg gcgctgacgg taaataaagg tgggatcagt
     2581 cagggtgaac tgacaggtgg cggaaacctg aatgttacag ggggaacgct ggctatcgag
     2641 gggcttaatg cacgctacaa tgcgttaacc agcattagcc caaatgcgga agtcagcctc
     2701 gataatactc aggggttagg cagaggaaat attgccaatg acggtctgtt aacgctaaaa
     2761 aacgtgactg gcgaactgcg taatagcata agcgggaagg gtatcgtgag cgcaaccgcc
     2821 aggacagatg tagagttgga tggcgataat agccgctttg tggggcaatt caacattgat
     2881 acaggcagcg cgctcagcgt caacgagcag aaaaacctgg gtgatgcttc cgttatcaat
     2941 aatggcctgc tcaccatctc cactgagcgt agctgggcga tgacgcacag tatcagcggt
     3001 agcggtgatg tgacaaaact gggtaccggg atcctgactc ttaacaacga ttccgcggcg
     3061 tatcagggta cgacggatat cgtggggggg ggaaattgct ttcggttccg actctgccat
     3121 taatatggca agtcaacaca ttaatatcca taacagcggt gtgatgtcgg gaaatgtcac
     3181 cactgcaggt gatatgaacg ttatgcctgg gggggcactg cgtgtcgcta aaaccactat
     3241 cggcggcaac ctggagaatg gcggcacggt tcaaatgaat agcgaagggg ggaaaccggg
     3301 gaatgtactg accgttaacg gcaactatac cggaaacaat ggcctgatga cgttcaacgc
     3361 gacgctgggc ggcgataatt cgcccaccga taagatgaac gtgaaaggcg atacccaagg
     3421 gaacactcgc gttcgggttg ataacattgg cggcgtcggt gcacaaacgg tcaacggtat
     3481 tgaactcatt gaggttggcg gtaattctgc aggtaacttc gcgctgacca ccggaactgt
     3541 cgaagctggg gcttacgtct acacgctggc taaagggaag gggaatgacg agaaaaactg
     3601 gtatctgacc agtaaatggg acggcgtaac gccagcggat acacccgatc ccatcaataa
     3661 tccccctgtt gtggatccgg aaggcccatc agtttatcgc ccggaggccg gaagctatat
     3721 cagcaacatt gccgcagcca actcgctgtt tagccatcgt ttacacgacc gtctgggtga
     3781 gccgcagtat acagattcac tgcattctca ggggtcggca agcagtatgt ggatgcgtca
     3841 tgtcggaggg cacgaacgtt caagggccgg tgacggtcag ctaaatactc aggctaaccg
     3901 ctatgtattg cagctaggcg gcgatttggc gcagtggagt agcaacgcgc aggatcgctg
     3961 gcatcttggc gtgatggcag gctacgccaa tcagcacagt aatactcaga gtaatcgtgt
     4021 gggttataaa tcggatgggc gcatcagcgg ttacagcgct gggctgtacg cgacctggta
     4081 tcagaacgat gcgaataaga ccggcgctta tgttgacagc tgggcgctgt ataactggtt
     4141 tgataacagc gtcagttccg ataaccgttc tgctgacgac tatgattctc gcggtgtgac
     4201 ggcctctgtt gagggtgggt atacctttga agcgggaaca tttagcggca gcgaagggac
     4261 gctgaatacc tggtacgtcc agccacaggc gcaaatcacc tggatgggtg tgaaagattc
     4321 cgaccatacc cggaaagacg gaacgcgcat tgaaacggaa ggcgacggaa atgtgcaaac
     4381 gcgacttggg gtgaaaacct acctgaacag ccatcaccag cgtgacgatg gtaaacagcg
     4441 tgagttccag ccttacattg aagcgaactg gatcaacaat agcaaagtct acgccgtgaa
     4501 gatgaatggt caaaccgtag gccgtgaagg tgcgcgtaat ctcggtgaag tacgtaccgg
     4561 ggttgaggcg aaagtaaata acaaccttag cctgtggggg aatgtcggtg tgcaactagg
     4621 tgataaaggc tatagcgata ctcagggcat gctgggagtg aaatatagct ggtaaaccgt
     4681 ataagccgca tgtcgagatg gcatgcggct taatattgcc gacttcaaac ggcgcatcaa
     4741 cgccttattt aaatcctcct ttttatccgc gatcgcggat atcgcagcgt ttatcccgta
     4801 gagcggataa gatgtgtttc cagattgact tatcctcact aaaggataaa acttataata
     4861 tccccttaag cggataaact tgctgtggac gtatgacatg atgagctttc agaagatcta
     4921 tagcccaacg caattggcga atgcaatgaa actggttcgc cagcaaaatg gctggacgca
     4981 gagcgagctg gcgaaaaaaa ttggtattaa gcaggcgacg atttccaatt tcgaaaacaa
     5041 ccctgacaat accacgctca cgacattttt taagatttta cagtcgcttg aactctcaat
     5101 gacgctatgc gacgcgaaaa atgcctcgcc agaatcaaca gaacagcaaa atctggagtg
     5161 gtaatgccta aacttgtcac ttggatgaac aaccagcggg taggcgagtt aacgaagtta
     5221 gccaacggcg cgcacacctt taagtatgca ccggagtggt tagcaagccg ttatgccaga
     5281 ccgttgtcac tttcgctgcc attgcagagg gggaatatca cctctgatgc cgtatttaac
     5341 ttcttcgata acctgttacc cgatagcccg attgtacgtg accggatcgt taaacgttat
     5401 catgccaaat ccagacaacc gtttgattta ttgtcagaaa tagggcgaga cagcgttggt
     5461 gccgtgacgt taatacccga agacgaaacc gtaacgcatc cgataatggc atgggaaaag
     5521 cttactgaag ccagacttga agaagtatta acggcttata aagcagatat cccgctaggc
     5581 atgattagag aagaaaatga ctttcgcatc tcggttgctg gcgcacagga gaagacagca
     5641 ctgctcagaa taggcaatga ctggtgcatt ccgaaaggaa taacgccgac gacgcacatc
     5701 attaaattac cgattggcga aatcaggcag cccaatgcga cgctcgatct cagccaaagc
     5761 gttgataatg agtattactg tctgctgctg gcgaaagaac ttgggttgaa tgttccggac
     5821 gcagaaatca ttaaagcggg aaatgtgcgc gcgttagcgg tcgaacgttt tgacaggcgt
     5881 tggaatgctg agcgaacggt tttacttcgc ttgccacagg aggatatgtg tcagacattc
     5941 ggtttacctt catcggtgaa atatgaatca gatggaggcc caggcatcgc gcggatcatg
     6001 gcttttttga tggggtccag cgaggcgctg aaagatcgct atgattttat gaaattccag
     6061 gtcttccagt ggttgattgg cgcaacggac ggtcatgcaa aaaacttctc cgtatttatt
     6121 caggctggcg gcagttatcg actcacgcca ttttacgaca tcatttcagc atttccggtc
     6181 cttggcggta cgggaataca catcagcgat ctcaaactgg caatggggct taacgcatcc
     6241 aaaggcaaaa aaacggcaat cgataaaatt tatccgcgac attttttggc gacagcaaag
     6301 gtgctgagat tcccggaagt gcagatgcat gaaatcctga gtgactttgc cagaatgatt
     6361 ccagcagcac tggataacgt gaagacttca ttaccgacag attttccgga gaacgtggtg
     6421 acggcagttg aaagcaatgt gttgaggttg catggacggt taagccgaga atacggtagt
     6481 aagtgagata tggggtttgg tcattgttaa tgagcatgac aatcatgacc gccaacgact
     6541 ggattcttcc ttggtttata ttggtgcgca taatgtatat tatgttaaat catgtctgag
     6601 tgatgcgaag tgcttttctg gtagtcgtta ttcgttcagg gttcaagaac ttaagcctct
     6661 cctctttcat aattggcctg tgcatggaga aatagcctgg ttattccctg ccccatgcta
     6721 agagcgcagt gtctgtcgca tagacactgc atacgaaaac accagagggt gctgttactt
     6781 atttaaggac ggatcaagcg ggaatgagtc cactccggta tcagaaatgg ctacgtctca
     6841 atgaagtcag gcgacagatg ctgaatgaac attacgatgt caccacagca gcctatgctg
     6901 tcggttacga aagctatccc atttcagtcg ggaatattcg cggatgtttg gagagtcacc
     6961 caagagagat attaccaggt taagaaagtc tgtcggacag ctttaataaa ccctgcactt
     7021 atctgtttag agcaattcgg tgttagtttc agcaagcaaa cattaaccat agctaatgat
     7081 ttatagccat attaaccatt ggtagctctt gacctttcct gacacttccc ttgttcgcaa
     7141 taatattctg tttagtcacg gtttataaat aacatgcata atgaaatcgt catgttattt
     7201 agcgacataa aatgtttttg caaatact
//
LOCUS       DAPOAV010000146         7192 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.147, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000146 DAPOAV010000000
VERSION     DAPOAV010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7192
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.147"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            79..264
                     /locus_tag="RN951_004139"
     CDS             79..264
                     /locus_tag="RN951_004139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529052.1"
                     /translation="MSRRYSSATITLVILFCRRPHCRKISVRQYYQKRVIFYPTTLQR
                     TACKKCLFLMRDIIISS"
     gene            225..344
                     /locus_tag="RN951_004140"
     CDS             225..344
                     /locus_tag="RN951_004140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001131457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDX2529053.1"
                     /translation="MPLSYAGYHHFIMMSLVSGEHNTPALSLQDESPGLVPAG"
     gene            379..722
                     /locus_tag="RN951_004141"
                     /pseudo
     CDS             379..722
                     /locus_tag="RN951_004141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311542.2"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
     gene            complement(1094..1360)
                     /gene="minE"
                     /locus_tag="RN951_004142"
     CDS             complement(1094..1360)
                     /gene="minE"
                     /locus_tag="RN951_004142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HDX2529054.1"
                     /translation="MALLDFFLSRKKNTANIAKERLQIIVAERRRSDAEPHYLPQLRK
                     DILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEELK"
     gene            complement(1364..2176)
                     /gene="minD"
                     /locus_tag="RN951_004143"
     CDS             complement(1364..2176)
                     /gene="minD"
                     /locus_tag="RN951_004143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020801817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HDX2529055.1"
                     /translation="MARIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDFDIGLR
                     NLDLIMGCERRVVYDFVNVIQGDATLNQALIKDKRTENLYILPASQTRDKDALTREGV
                     AKVLDDLKAMDFEFIVCDSPAGIETGALMALYFADEAIITTNPEVSSVRDSDRILGIL
                     ASKSRRAENGEEPIKEHLLLTRYNPGRVSRGDMLSMEDVLEILRIKLVGVIPEDQSVL
                     RASNQGEPVILDINADAGKAYADTVERLLGEERPFRFIEEEKKGFLKRLFGG"
     gene            complement(2200..2895)
                     /gene="minC"
                     /locus_tag="RN951_004144"
     CDS             complement(2200..2895)
                     /gene="minC"
                     /locus_tag="RN951_004144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HDX2529056.1"
                     /translation="MSNTPIELKGSSFTLSVVHLHEAEPKVIHQALEDKIAQAPAFLK
                     HAPVVLNVSALEDPVNWSAMHKAVSATGLRVIGVSGCKDAQLKAEIEKMGLPILTEGK
                     EKAPRPAPTPQAPAQNTTPVTKTRLIDTPVRSGQRIYAPQCDLIVTSHVSAGAELIAD
                     GNIHVYGMMRGRALAGASGDRETQIFCTNLMAELVSIAGEYWLSDQIPAEFYGKAARL
                     QLVENALTVQPLN"
     gene            3415..3783
                     /locus_tag="RN951_004145"
     CDS             3415..3783
                     /locus_tag="RN951_004145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgJ family protein"
                     /protein_id="HDX2529057.1"
                     /translation="MNMMRIFYIGLSGVGMMFSSMASGNDAGGLQSPACGVVCDPYIC
                     VNSDGISPELTRKYLGEKAAENLQSLQGYDPSEFTFANGVFCDVKEKLCRDDRYFGVD
                     GKRSGKINQTTTKMLFMCRE"
     gene            complement(3886..4287)
                     /locus_tag="RN951_004146"
     CDS             complement(3886..4287)
                     /locus_tag="RN951_004146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inhibitor of g-type lysozyme"
                     /protein_id="HDX2529058.1"
                     /translation="MKIKSIRKAVLLLALLTSTSFAAGKNVNVEFRKGHSSAQYSGEI
                     KGYDYDTYTFYAKKGQKVHVSISNEGADTYLFGPGIDDSVDLSRYSPELDSHGQYSLP
                     ASGKYELRVLQTRNDARKNKTKKYNVDIQIK"
     gene            4529..4822
                     /locus_tag="RN951_004147"
     CDS             4529..4822
                     /locus_tag="RN951_004147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309701.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgL domain-containing protein"
                     /protein_id="HDX2529059.1"
                     /translation="MFCVIYRSSKRDQTYLYVEKKDDFSRVPEELMKGFGQPQLAMIL
                     PLDGRKKLVNADIEKVKQALTEQGYYLQLPPPPEDLLKQHLSVMGQKTDDTNK"
     gene            4894..5553
                     /locus_tag="RN951_004148"
     CDS             4894..5553
                     /locus_tag="RN951_004148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDX2529060.1"
                     /translation="MYQHHNWQGALLDYPVSKVVCVGSNYAKHIKEMGSAVPEEPVLF
                     IKPETALCDLRQPLAIPSDFGSVHHEVELAVLIGATLRQATEEHVRKAIAGYGVALDL
                     TLRDVQGKMKKAGQPWEKAKAFDNSCPLSGFIPAAEFTGDPQNTTLSLSVNGEQRQQG
                     TTADMIHKIVPLIAYMSKFFTLKAGDVVLTGTPDGVGPLQSGDELTVTFDGHSLTTRV
                     L"
     gene            5645..6091
                     /locus_tag="RN951_004149"
     CDS             5645..6091
                     /locus_tag="RN951_004149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309703.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgN family cysteine cluster protein"
                     /protein_id="HDX2529061.1"
                     /translation="MSDVPFWQSKTLDEMSDAEWESLCDGCGQCCLHKLMDEDTDEIY
                     FTNVACRQLNIKTCQCRNYERRFEFEPDCIKLTRENLPTFEWLPMTCAYRLLAEGKDL
                     PAWHPLLTGSKAAMHGERISVRHIAVKESEVIDWQDHILNKPDWAQ"
     gene            complement(6298..>7192)
                     /gene="hlyE"
                     /locus_tag="RN951_004150"
     CDS             complement(6298..>7192)
                     /gene="hlyE"
                     /locus_tag="RN951_004150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415700.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hemolysin HlyE"
                     /protein_id="HDX2529062.1"
                     /translation="DKTVEVVKNAIETADGALDLYNKYLDQVIPWQTFDETIKELSRF
                     KQEYSQAASVLVGDIKTLLMDSQDKYFEATQTVYEWCGVATQLLAAYILLFDEYNEKK
                     ASAQKDILIKVLDDGITKLNEAQKSLLVSSQSFNNASGKLLALDSQLTNDFSEKSSYF
                     QSQVDKIRKEAYAGAAAGVVAGPFGLIISYSIAAGVVEGKLIPELKNKLKSVQNFFTT
                     LSNTVKQANKDIDAAKLKLTTEIAAIGEIKTETETTRFYVDYDDLMLSLLKEAAKKMI
                     NTCNEYQKRHGKKTLFEVPEV"
BASE COUNT         1850 a         1581 c         1704 g         2057 t
ORIGIN      
        1 agaagtgtca ttgactgtta acgcaatgtt gtaaaggtaa gataatctga tttatcaata
       61 ttattgtgtg atttttatgt gagcagaaga tattcatcag caacgattac attagtcatt
      121 ttattttgcc gacggcctca ttgtcgaaag ataagcgtac gacagtatta tcagaaaaga
      181 gtgatttttt atccaactac acttcagcgc actgcgtgta aaaaatgcct ctttcttatg
      241 cgggatatca tcatttcatc atgatgtctt tggtgagcgg tgaacacaat acacctgcgc
      301 tgtctcttca ggatgaatcc cctggtctgg tgcctgcggg ctgatgttgc agcagagctt
      361 aggtcactta gacgctacta tcatttatcc aatggcatgg aatcgaaatc agtcgatacc
      421 cgcagtatat atcgtgaact gggtgcaacg ctgagttaca acatgcgcct ggggaacggt
      481 atggaaatga accctggctg aaggcggctg tgcgcaaaga atttgtcgat gataaccggg
      541 tgaaggtgaa taatgacggt aatttcgtca atgatttgtc gggcagacgt ggaatatacc
      601 aggcagctat taaagcctca ttcagcagta cgtttagcgg acatctcggg gtggggtata
      661 gccatggtgc cggtgtggaa tccccgtgga acgcggtggc tggtgtgaac tggtcgttct
      721 gaccatcaac gattaaactg cgcttcggcg cagttttcgt ttacaggatg ttgaaaggga
      781 aaattctggg gcaaaaaaag cccgccagtt acggcgggaa acctcatcct atgggagaac
      841 aatgaataat gaaattgcgg ggttatcatc tcccagtata tccatactaa caataaggtt
      901 atttactcaa ccaggcataa acattttgtt ttgtgcgtgg gaacagcctt aaggtgtaaa
      961 gggggaggtg gaaatagcaa tgaggagtat cagcaagaat actcgccgct ttaccacaac
     1021 gtggatgaga gggatgaaaa actcaaggca gagataactc tgccttgaag ataaatgcgc
     1081 ttttacagcg ggcttatttc agctcttctg cttccggtaa ggtcacgttc agctcaagaa
     1141 tagaaatatc gccatctttt tgctcaagct gtacggttac catctcagga tcaatttgta
     1201 cgtatttaca aatgacctca agaatatctt tacgcaactg cggcagataa tgcggttctg
     1261 catcgctgcg acggcgttca gcaacaataa tctgcagccg ttcttttgca atgttggctg
     1321 tgtttttctt ccgcgagaga aagaaatcga gtaatgccat aacttatcct ccgaacaagc
     1381 gtttgaggaa gcctttcttc tcttcttcaa tgaagcggaa aggacgttct tctcccaaca
     1441 gacgttctac ggtatctgcg taggctttac ccgcatcggc gttaatgtcg agaatgaccg
     1501 gttcaccctg gttagaggcg cgcaatactg attgatcctc tgggatcacg ccgacgagtt
     1561 tgatgcgcag gatctccagc acatcttcca tgctcagcat gtcacctctg cttacgcggc
     1621 ctgggttata gcgcgttaac agcaggtgct ctttaatagg ctcttcgcca ttttctgcgc
     1681 ggcgtgattt cgacgccaga atgcctaaaa tacggtcaga gtcgcgtact gaggagactt
     1741 ccgggttggt ggtaataatg gcttcgtctg caaaatagag tgccattaac gcaccggttt
     1801 caatccctgc cggggagtca caaacgataa attcaaaatc catcgctttc agatcatcaa
     1861 gaactttggc gaccccttca cgggtgaggg catctttatc gcgtgtttgc gatgccggca
     1921 gaatatagag attttcagta cgcttatctt taattaacgc ctgatttagc gttgcatcgc
     1981 cctgaatgac gttgacgaaa tcgtaaacga cccggcgttc acaacccata atcaggtcga
     2041 gattacgcag gccgatatca aaatctatca cgacagtttt ctttcccttc tgggccaaac
     2101 cagtggcgat ggccgcgctg gaggttgtct taccaacacc ccctttgccc gaagtaacaa
     2161 caataatgcg tgccatagaa attccttgtt aaaaagggat caatttaacg gttgaacggt
     2221 caaagcgttt tcgactaact gcagtcgcgc cgctttgcca taaaattctg ctgggatttg
     2281 atcactcagc cagtattcac ctgcgatgga caccagttcc gccatcaggt tcgtacaaaa
     2341 tatttgcgtt tcccggtcac cacttgcccc tgccagcgca cgaccgcgca tcatgccata
     2401 gacatgaatg ttcccatcgg caatcaattc ggccccagcg ctaacgtggc ttgtaacaat
     2461 cagatcacat tgtggagcat aaatacgctg accggaacgc accggggtat ctattaaacg
     2521 cgtttttgtg accggcgttg tattttgcgc tggagcctgc ggtgtgggag ctggacgtgg
     2581 cgctttttcc tttccttccg tcaggatagg cagccccatc ttttcaattt cggctttaag
     2641 ttgcgcatct ttgcagccac ttacgccaat aacccgcaaa ccggttgccg aaaccgcctt
     2701 atgcatcgct gaccagttta ccgggtcttc cagtgcactg acgttgagta caacgggggc
     2761 atgttttaaa aatgcggggg cctgagcgat tttgtcttcc agcgcctgat ggataacctt
     2821 aggttctgcc tcatgcagat gaaccacaga taaagtgaag ctactgcctt taagctcgat
     2881 tggcgtgttt gacatcctgg ccttactcaa ttagctatta atcatcgcca gcgcgcgatg
     2941 atgttccgaa gactataagg catgttatag tctggattat attgaggcaa gtcaccctcc
     3001 catttattca gagtaaaagt ctattctgtg ataaatggcg ctgattcata gcttaaaaaa
     3061 tacccttgtc aatcaaccca ttgccgtcgt acttttgatt gttcttattt acgcttcctt
     3121 tttccgcacc ctaatcgtga cagcatctcc agacctgttt aaatatccag tattgaggca
     3181 agtgtatttt ttcaccacgc caggctttct taactttcca ttttttgcgg catcattaaa
     3241 gaacagatac ccgttatctt aatatccgcc acagaattgc tctatcatag aaaccgcaga
     3301 agacgtctga tacttctgtc aggtcatcgt aactcgtcca ggtcagcggt tttgattacg
     3361 gattgatgat gaaatgagca taagtgttgt acggttggat tatcaggatg tgctatgaat
     3421 atgatgcgta ttttttatat cggattgtca ggtgtgggga tgatgttctc atcaatggcg
     3481 tctggaaatg acgctggcgg acttcaatct ccggcgtgcg gcgttgtttg cgacccgtat
     3541 atttgtgtga actcagatgg catttcccca gagttaacaa ggaaatatct cggcgaaaaa
     3601 gccgctgaaa acttacaatc attacaaggc tacgatccca gcgaatttac attcgctaac
     3661 ggtgtatttt gcgatgttaa agaaaaatta tgtcgtgatg atcgttattt tggtgtggat
     3721 ggtaagcgga gtggaaaaat caatcaaacc accacaaaga tgttatttat gtgtcgtgag
     3781 tgatgtcttg tttacattat gttctattcg tcattaacct cttgagcgac agagaggagt
     3841 ggggcattaa cgtttatgac ggggagagtc cccgtcggtt gacatttact taatttgaat
     3901 atcgacgtta tattttttag ttttgttttt acgggcgtcg tttcgggttt gcaacactcg
     3961 cagctcatat ttgccagaag cagggagtga gtattgtccg tgactatcga gttctgggga
     4021 atatctggat aaatcaactg aatcatcgat tcctggcccg aagaggtaag tatcagcgcc
     4081 ttcattagag atactcacat gcactttctg accttttttg gcatagaagg tatatgtatc
     4141 gtaatcgtat ccctttattt cgccggagta ctgagcgctg ctatggcctt ttctgaactc
     4201 aacattgaca ttcttacccg cagcaaagct cgtggaggtt agcagtgcaa gcagcaatac
     4261 agccttcctg atgctcttga ttttcattgg tagtctcctg ttcagaatga gtacgatgaa
     4321 ctgttataat ataacaatcc ctaacgggag aattccagtg gctttcctgc gttcggtaaa
     4381 atcacgttgc ggcatttttg ccggggggat tacttataaa gggggcatgg actcaacaaa
     4441 ccgtagaaat ctacagctgg ctggcttgtg gcgcgggttt cattgatgtt agcttatgcc
     4501 aaaacctggc atcttaaaga gtaaaagtat gttttgtgtg atttatcgaa gcagcaagcg
     4561 tgaccagacc tatttatatg tcgaaaaaaa agacgatttt tcgcgtgttc ctgaggaact
     4621 gatgaaaggt tttggtcagc ctcagttagc gatgattctg ccgctggatg ggcggaagaa
     4681 actggtcaat gccgatattg aaaaggttaa acaggcatta accgagcaag gttactattt
     4741 gcagttaccg ccaccacccg aagatttgct gaagcaacat ctttccgtca tggggcagaa
     4801 aacagacgac actaacaaat aaccgatatc cggcggtggc attatctttg tcggcgcggg
     4861 ttttcatatc cacgataagg tgaggggaac gttatgtatc aacatcacaa ctggcaaggt
     4921 gcgctgctgg attatccggt gagtaaagta gtctgtgttg gcagtaacta tgccaaacat
     4981 attaaagaga tgggcagcgc agtgcccgaa gagccagtgc tgtttattaa accagaaacg
     5041 gcactgtgcg atctgcggca gccattggcg atcccatccg atttcggttc agttcatcat
     5101 gaagtcgaac tggcggtgtt gattggcgcg acactgcgtc aggctacgga agagcatgtc
     5161 cgcaaagcca ttgccggtta tggcgtggcg ctcgatctga cattgcgtga tgttcaggga
     5221 aaaatgaaga aagccgggca gccgtgggaa aaggctaaag cgtttgataa ctcttgtccg
     5281 ctttccgggt ttattcccgc ggcggaattt accggcgacc cgcaaaatac aacgctgagc
     5341 ctgagcgtaa acggcgaaca acgccagcaa ggtacgactg cggacatgat ccataaaatc
     5401 gttccgctga tcgcttatat gagcaagttt tttaccctca aggccggtga cgttgtgttg
     5461 acaggcacgc ctgatggcgt cggcccgttg caaagcggtg atgagctgac agtcactttc
     5521 gatgggcatt ctttgacaac tcgcgttttg taatactttt tgccgcctga aagcggcggc
     5581 aaaacttgca tcgctgtgcc agactggtta taaggtgcgt tttaacgtaa tggcggaaca
     5641 cctgatgagc gatgtacctt tctggcaaag taaaaccctg gacgaaatga gcgatgcgga
     5701 atgggagtcg ttgtgtgatg gttgcggtca gtgttgcctg cataaactga tggatgaaga
     5761 caccgacgaa atctacttca ctaacgtcgc ctgtcgccag ctcaatatta aaacctgtca
     5821 atgtcggaac tacgaacgtc gtttcgagtt tgaacccgac tgcattaaat taacccgtga
     5881 aaatctgcca acattcgaat ggctgccaat gacctgcgct tatcgtttgc tggcggaagg
     5941 taaagattta cctgcgtggc atccgctact tactggttcg aaagcggcaa tgcatggtga
     6001 acgtatctct gtgcgtcata tcgcagtgaa agaatcagaa gtgattgact ggcaggatca
     6061 tatcttaaat aaacctgact gggcgcagtg ataaatttaa tagatgctga tgggggcttt
     6121 cttaatatac gtctggatgc tcgccatttc gtagccctgt ttttgaaagc gctctgtcat
     6181 aatgagagtt acccgatacc ttattatcaa caggtaactc tcaatcttta aaaaacgtct
     6241 gtgtttttaa atgtgataaa ccttatacct tgagtacatg gagagaataa tcgcttatca
     6301 gacttcaggt acctcaaaga gtgtcttttt accgtgtctt ttctgatact cattacaggt
     6361 gttaatcatt tttttggccg cttcttttag caaagaaagc attaaatcat cataatcaac
     6421 gtagaatctg gttgtttcag tttccgtttt tatctcaccg atggcggcta tttcggtggt
     6481 taatttcaat ttggcggcat cgatatcttt attcgcttgt ttaaccgtgt tagacagggt
     6541 ggtaaagaaa ttctgcacag attttaactt gttcttcaat tctggaatca gttttccttc
     6601 aactacgccc gcagcaatag aataggaaat gattaatcca aatggaccgg cgacgacacc
     6661 ggctgcggca ccggcatatg cttccttcct gattttatct acctgtgact ggaaatagct
     6721 gcttttttct gaaaaatcat tggttaactg gctatctaac gccagcagtt tcccggaagc
     6781 gttgttgaaa ctttgtgagc ttaccagcag ggatttttgc gcttcattca gcttcgtgat
     6841 gccgtcatcc agtaccttaa tgagaatgtc tttctgggcg gatgctttct tctcattgta
     6901 ctcatcaaat agcaaaatat acgctgcgag caattgcgtc gcaacaccac accattcata
     6961 cactgtttgg gttgcttcaa aatacttatc ctggctatcc ataagtaagg ttttaatatc
     7021 gccgactaaa acggaggctg cctgtgaata ctcctgttta aagcgactta actcttttat
     7081 ggtttcatca aaggtctgcc aggggatgac ctgatcgaga tatttattat aaagatctaa
     7141 tgctccatct gcggtttcga ttgcgttttt aactacttct accgttttat ct
//
LOCUS       DAPOAV010000147         7159 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.148, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000147 DAPOAV010000000
VERSION     DAPOAV010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7159
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.148"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..158
                     /locus_tag="RN951_004151"
     CDS             <1..158
                     /locus_tag="RN951_004151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="HDX2529063.1"
                     /translation="ISKRYTQRIERHNLNLRQHLARLGRKLLSFSKSVELHDKVIGHY
                     LNIKHYQ"
     gene            complement(178..243)
                     /locus_tag="RN951_004152"
                     /pseudo
     CDS             complement(178..243)
                     /locus_tag="RN951_004152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280980.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="omptin family outer membrane protease"
     gene            476..580
                     /locus_tag="RN951_004153"
                     /pseudo
     CDS             476..580
                     /locus_tag="RN951_004153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477168.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            920..1177
                     /locus_tag="RN951_004154"
     CDS             920..1177
                     /locus_tag="RN951_004154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016230781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm development YmgB/AriR family protein"
                     /protein_id="HDX2529064.1"
                     /translation="MHSDYYNMVFGEKLANILYEANSQFFYERNVIEEAVNALFCERE
                     IINNKNIIKKLMFFLSDVNHTKKDVVQSALNIIIDITSGDI"
     gene            complement(1497..1628)
                     /locus_tag="RN951_004155"
                     /pseudo
     CDS             complement(1497..1628)
                     /locus_tag="RN951_004155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1910..3268
                     /locus_tag="RN951_004156"
     CDS             1910..3268
                     /locus_tag="RN951_004156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase-like activity of phytase family
                     protein"
                     /protein_id="HDX2529065.1"
                     /translation="MKRKIIPVLIGCTLSFSALAAQPTAERYVVSFPEGTHVNYAGAF
                     ASAFPNGLPVGIGSGLLFTGKQGDALTFATITDRGPNADSPKEGKNETKIFVTPDFAP
                     LLMTIRVQNGKAEAIDPRPLHDDKGAINGLPLASDVIGSTNEVAFSDTLHRLKGDNRG
                     LDTEGITPDGKGGYWLCDEYGPFLINIDSKGKILAIHGPQAAEGEKAIAGGLPNILKW
                     RQANRGFEGLTRMPDGRIIVAVQSTLDIDAKSKKKALFTRLVSFDPASGKTAMYGYPI
                     DSAAYSKNSDAKIGDIVALDNQHILLIEQGRDKNNRMRNLIYEVDLNKASDLSGFDKP
                     GEYPEFDDEKTLSQRGITLAQKTQVVDLRSLGWQQEKAEGLALIDSKTLAVANDNDFG
                     VKVAMQHPVEGKTFKDYRVNAEGKLTLDDKQVETTLRVKPLEKPESDSELWIVTLPEA
                     LK"
     gene            complement(3507..4891)
                     /locus_tag="RN951_004157"
                     /pseudo
     CDS             complement(3507..4891)
                     /locus_tag="RN951_004157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            complement(4941..5288)
                     /gene="tnpB"
                     /locus_tag="RN951_004158"
     CDS             complement(4941..5288)
                     /gene="tnpB"
                     /locus_tag="RN951_004158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019104956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDX2529066.1"
                     /translation="MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVF
                     IFRGRSGSQVKLLWSTGDGLCLLTKRLERGRFAWPSARDGKVFLTQAQLAMLLEGIDW
                     RQPKRLLTSLTML"
     gene            complement(5285..5620)
                     /locus_tag="RN951_004159"
                     /pseudo
     CDS             complement(5285..5620)
                     /locus_tag="RN951_004159"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6020..6454)
                     /locus_tag="RN951_004160"
                     /pseudo
     CDS             complement(6020..6454)
                     /locus_tag="RN951_004160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001556209.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
     gene            complement(6442..6843)
                     /locus_tag="RN951_004161"
     CDS             complement(6442..6843)
                     /locus_tag="RN951_004161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004020115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529067.1"
                     /translation="MYAKSFIALDGNGRLTGARTAQDAPYANYTCHLCGSALRYHPQY
                     DTELPWFEHTDDRLTEHGQQCPYVRPERREIQLIKRLQQFVPDALPVVRKASWHCRQC
                     HHDYYGEQYCTHCQTGGFSIPRTTQEEICEF"
     gene            complement(7021..>7159)
                     /locus_tag="RN951_004162"
     CDS             complement(7021..>7159)
                     /locus_tag="RN951_004162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001437348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HDX2529068.1"
                     /translation="SIPKLTAPVSAILAVAGVEHDWRANIRQTKSMGCCLAATMYPLA
                     H"
BASE COUNT         1781 a         1830 c         1811 g         1737 t
ORIGIN      
        1 ttatcagcaa gcgttacact cagcgcattg agcgacataa tctgaatctg agacaacatc
       61 tggcaaggct gggacggaag ttactgtcgt tctcaaaatc ggtggagttg catgacaagg
      121 tcatcgggca ttatctgaac ataaaacact atcagtaagt tggagtcatt acctcctccc
      181 gaactcaaag ctatcataca gataattact ggttaaccct atatagggca ttttaaagtg
      241 ttgtgatctt acccagcaat agtggacacg cggctaagtg agtaaactct cagtcagagg
      301 tgactcacaa gacaaaacag tttcaaccag taaaaaaacg taaacaccat tcgcatgaat
      361 ttcgtagtta agatctgaag cttgcagaat gcatcggtgt tactgccgga gtccgtgaac
      421 ttagtctgca tgaatcacca cagctttaca tctgtcgcag taaacagcaa aatcagcaaa
      481 cttacttaat tatatcgagt gcgattacaa tcgctggcga tggtacagtt ggtgtggcgg
      541 tctcagtccg gaacaatttg aaaatcagaa tctcacttaa aacggcatcc attttacaaa
      601 agatggccgt ctgtgtattt gtaatgaata ccttctacat gtttagagtg cataatccac
      661 gacaaggcga tatcctaaaa attagctagc aggcaacttt gatggcatag ataatgtttt
      721 tagtaaaaaa gagttgactg aatataatac agcctcttcc tacataagaa ggaatgtgct
      781 cacaaaaaaa aaccattagt ctgcttcctg ttcttacaat aatcagtatt atgtatttta
      841 tttatatagc aaaatatgct tgttacacct gtcataatta ggcatggtaa aattattgat
      901 tgaaccctgg gggagaaaga tgcacagtga ttattataat atggtttttg gtgaaaaatt
      961 ggccaatatt ttatatgaag ctaactctca atttttttac gagagaaatg tcatagaaga
     1021 ggcagtcaac gctttattct gtgagcgtga aataataaac aacaagaaca taataaagaa
     1081 gctgatgttc tttttgtcag atgttaatca caccaagaaa gatgttgttc agagcgcact
     1141 taatattatc attgacatta catcaggtga tatttgagat tttacataaa agataatctt
     1201 tcaaggagtc ttatctgaaa acgaaatata tagtccctct cgttttgtaa tatcgattgg
     1261 ctttgttgaa tcggttacgt accccggagc cggtcatatt ttcaggtaat acacacgctt
     1321 tcagacattt cggctttcgt cattttggta tcatgggcat agcttctgct acctgaccat
     1381 cataatcacg cagcttcagt gaagcagtga ccacctgttt aacccggtgt atcgttatga
     1441 tcttatccag caattgaacc gccccgggtt tcctggagag tgttttatct gtgaactcag
     1501 gctgccagat catcgtttcc gatggaagca taataagctt tttctgcttc tgccggtggg
     1561 atatggccct gcctttccag caatcgtcga ttgttatacc agtccaccca cgtgagtgtg
     1621 gtcagctcat catactgaca cgtgcattac ccctaccgcg ataatgcaac cgtacaatat
     1681 agggcgtttc ctaaacgcag ccctcatcac tccaatccaa caagacacag catttttgat
     1741 cacgaagaaa gacaaataat ttccgtaaat gtttccgttg ttacaaataa caacagtgtt
     1801 ttacatttct ttggcctcag gcccgcgcat gttgccattc gatgtcattt tcctgactcg
     1861 tttcttcttt atggtgtagt gtgatcttca ctttatggat gctaacaata tgaaaagaaa
     1921 aattattccc gtgctaatcg gttgtacgct ctctttctct gccctggcgg cacaacctac
     1981 ggctgagcgc tatgtcgtca gttttccaga aggcacgcac gtgaactacg ccggcgcatt
     2041 tgccagtgca ttcccgaacg gccttccggt tgggataggt tctggcctgc tgttcaccgg
     2101 taaacagggc gatgccctga cattcgcaac cattaccgat cgcggtccga acgcggattc
     2161 accgaaagag gggaaaaacg aaactaaaat tttcgttacg ccagatttcg cgccgctgct
     2221 gatgacgatt cgtgtacaaa acggcaaagc ggaggccatc gatccccgtc ctctgcatga
     2281 cgataaaggc gcgatcaacg gtctgccgct ggcaagcgac gtgattggct ccaccaatga
     2341 agtggccttc agcgacacgt tacatagact gaagggggat aatcgcgggc tggatacgga
     2401 agggatcact ccggatggta aaggaggtta ctggctgtgc gatgagtatg gcccgttcct
     2461 gattaacatc gacagtaaag ggaaaatcct ggcaatccac ggtccgcagg cggcggaagg
     2521 ggaaaaagcg attgcgggcg gtttgccaaa tatcctcaaa tggcgtcagg cgaaccgcgg
     2581 ctttgaaggc ctcacccgta tgccggacgg gcgtattatt gtcgccgtgc aaagtacgct
     2641 ggatatcgac gctaagagca agaaaaaggc gctgtttacg cgtctggtga gcttcgatcc
     2701 ggcaagcgga aaaaccgcga tgtacggtta tcctatcgac agcgcggcct acagcaaaaa
     2761 cagcgacgct aaaatcggag acatcgtggc gctcgataac cagcacatcc tgctgatcga
     2821 acagggaaga gataaaaaca acagaatgcg taacctgatt tacgaggtcg atctcaataa
     2881 ggcgagcgac ctgtcaggct tcgacaagcc gggtgagtat ccggagtttg atgatgagaa
     2941 aaccctgtca cagcgcggca ttacccttgc gcagaaaacg caggttgttg atctgcgctc
     3001 cttgggctgg cagcaggaga aggctgaagg gttggcgctg atcgacagca aaacgctggc
     3061 ggtggcgaac gataacgact ttggcgtgaa ggtggcgatg caacatccgg tcgagggcaa
     3121 gacattcaag gattatcggg tgaacgcgga aggaaagctg acgcttgacg acaagcaggt
     3181 tgaaacgacc ctcagagtga agccactgga gaaaccggag tctgacagtg aactgtggat
     3241 tgtgacgctg ccggaagcgt tgaaataagt ttataaggta cggacagcag tatcgcttag
     3301 tttttcaaat tcatgtatgt gaacaatatt ggggttccgg cgtagacccc caatgaaagc
     3361 gtcaccacgt gaaaacatgc ctgcacggtt tacacgtcat cccatggtgg cagccggtta
     3421 actttcctgc gccaccagtg gaaaaaggcc ataagcagtc cgaacaaaag taagcgtaca
     3481 gcgagggccg tattgacggg gatgtgttat tcagctggca gtgctatgcg ccacggaagc
     3541 agttcgctga cccggttgac cggccagtct gctatgacgc caagcacatg gcgaaggtag
     3601 ctttctggat ccacgtcatt cagtttgcac gtcccgatca ggctgtacag tagcgctccc
     3661 cgctcaccac catggccaga gccgaagaac agggtcttca tcttttcacg caaccagctt
     3721 tccagggatt tcaacagcgg tttcgttttt cgctgacgtt cagcaagccg ctgctctgcc
     3781 ggcattcccc ttatatccgc ctctatggcg tacaactgac cgatctgctc cagggcttct
     3841 tccgtcagtg ctgacgggat gcggacgtgc acatcgtgga tctttcggcg ggcatgagcc
     3901 cagcaggcag cttccgttat cccaccattg cgatacagct cgttgaaccc ggcgtacgca
     3961 tccgcttgca gcacaccgct gaagcaagca agatgagtct gcggatggat gccttttctg
     4021 tccgggctgt aagcgaacca cactgcaggt gccaacgctg acccggcatt gcggtcatca
     4081 cgaacatacg cccacaaccg cccggtcttc gtcttcttat tacccggcag cagtacctgg
     4141 accggggtat catcggcatg gagtttgccg tcagtcatga catagccatg aagcgcctct
     4201 tccagcggag acagcagccg gcagcatgca tccacccagc ccgacagcag tgaacggctc
     4261 agctccacac cttgccggct gtatatttct gactggcaat acagcggggt gtgctctgca
     4321 tacttcgagg tcagcacgcg ggccagcagc cccggtccgg cgataccccg ctcgatgggc
     4381 cgcgaaggtg caggtgcctg cacgatggca tcgcactgag tacaggcatg tttttcccgt
     4441 accgtccgga taacccggaa ggcgctacgc atcaactcca gctgttcggc ggtatcctcg
     4501 cccagatagc tcagtgaacc gccgcagttc gggcagcacg gcgccgcagg caacagtcgc
     4561 ttttcgtcac ggggtagtga ttcagggaac ggcttacggg tgcgggtctg acgcaacgga
     4621 cgctgtactg ccgggtcata caccctacca gtcagcgtat cgctctcttt ctgaagccgg
     4681 ttcagatcgg cttccatttg tgcgatacgg cgggagactt tttcggaacg actgccgaag
     4741 ttcatccggc ggagtttatc cagctgcgcc tgcagatgtc tatttcgcgc tcccggttgc
     4801 tcagcttttc ctgcagggcg tggatcagcg cttcctgttc ggccaggcgc tgtttcagca
     4861 ggaagatgtc gtcagaagag atgtcgttca taagcccgta ttttaccggg cttattctgt
     4921 gacaaccagg ataaagagat ttacagcatg gtcagggagg tcagcagccg cttgggctgt
     4981 cgccagtcga taccttccag cagcatcgcc agctgcgcct gcgtaaggaa cactttgcca
     5041 tcacgggctg acggccaggc gaagcgccca cgctccagcc gtttggtcag gaggcacagt
     5101 ccgtcaccgg tggaccacag cagtttaacc tgactgccgc tgcggccccg gaaaatgaaa
     5161 acatggccgg acatgggatc gtctttcagc gccgtttgta ctttcgcagc caggccgttg
     5221 aagccatttc tcatatcggt gataccggca accagccaaa ttttggtccc ggaaggtaac
     5281 gggatcatcg cttcagttcc tgtatcagca gagtcaggag cttttcgctg acattgccat
     5341 tgaagcggag cgtcccgtgc cggaacgtta cctcacagct gatactgagg gtttccgggt
     5401 cctctgcgag cgattctggc tgttcggcag ctgcatcgag agtcacagga agtagctggg
     5461 ggctctctga agaaggtaat agcagctttc cctcgcgcca ttgttgtcgc catttgaaca
     5521 acagattggc gttaatgcca ttttcaagag caagttttga gatggatatc ccgggttcac
     5581 aggaggcagc aacgagctgc tgtttaaatt cgggaggata attagggcag ccttttcacc
     5641 tgccgggagt cacatttttc tgcatatctg acactttggt tcccactact tatttggtgg
     5701 acaccacttt gtctaattcg tcagattctg accagacggt tcaggctgta cgcttaccac
     5761 tattttatcc ctgttgaatt tggttaagcc ggtgcagacg cgccgggaaa cgcacacctg
     5821 aaccggcaca ataaaataca atacaacccc ctgttactgg agatacgaat ggaatgacga
     5881 ggcagcctgt cagtcacagg gggctgttgg cataaaatca acggaaaggc caccaacacc
     5941 ggaattaagc tccacagtcc ccgcactggc aatccattcc cgggaaaggc atcaccgcaa
     6001 actgctccgg aggcaaccat tacagcctct gtaacggatt atcagccctg gcatcttccg
     6061 acggcacctc ctgccgcccc cacgccctgc tgtatacccc ggtaccgcag cgtgggcagc
     6121 acttttcccc ctcataatct tcgtcacaca tcacacaaaa ccactttctc accttcaccg
     6181 tataatccgg aaccgtcatg ccctgcagat gcaaacgacg ggcctctttc tccgccgggt
     6241 caagccaggt acatcgcagc aggatttttt cagcgacagt catctagtca tgttcaaacc
     6301 acggtggttg tccgtcattg ccccgctgaa gtgttaacgg gcatccacag gacacacagc
     6361 acaaaacgtc ctgtcggttg tgcttcgcag cttctttcgc cgtaacaaaa tggcctttgc
     6421 tgtcattcgc catataacag ttcagaattc gcatatttcc tcctgagttg tccggggaat
     6481 actgaatcct ccggtctggc agtgtgtgca gtactgctcc ccataataat cgtggtgaca
     6541 ttgtctgcag tgccagctgg ctttacgcac cacgggtaag gcatccggta cgaattgctg
     6601 cagacgttta atcaactgta tttctctgcg ctccggcctg acataagggc actgttgacc
     6661 gtgctctgtc agcctgtcgt cagtgtgttc aaaccaggga agttcagtgt cgtattgcgg
     6721 atggtatctg agtgcactgc cacacaagtg gcaggtgtag ttagcataag gtgcgtcctg
     6781 tgcagtacgg gcgcccgtca gacgtccgtt gccatcaaga gcgataaagg attttgcgta
     6841 catagtcata ttccttagcc gccagacgac acgcaggcaa cagccgtccc ggtacgggca
     6901 gcgtggtcag ggtgtgaatg gcggttcagt taaaatctgg actggagttt gggtaaagca
     6961 ggctggttgc tgttacagca ctgtggttgt cacacaatgg aacactgacg taaaaaacag
     7021 tcagtgggcg agtggataca tcgttgccgc cagacaacaa cccatacttt tggtttgccg
     7081 gatattggcg cgccagtcgt gctcaactcc ggctacagcc aaaattgcgc tcaccggtgc
     7141 agtgagcttt ggtatgctc
//
LOCUS       DAPOAV010000148         7137 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.149, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000148 DAPOAV010000000
VERSION     DAPOAV010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7137
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.149"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..1698
                     /gene="bglF"
                     /locus_tag="RN951_004163"
     CDS             <1..1698
                     /gene="bglF"
                     /locus_tag="RN951_004163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIABC"
                     /protein_id="HDX2529069.1"
                     /translation="VVIGNHVADVFLAVNSVAGLDEKAQQAPENDDKGNLLNRFVYVI
                     SGIFTPLIGLMAATGILKGMLALALTFQWTTEQSGTYLILFSASDALFWFFPIILGYT
                     AGKRFGGNPFTAMVIGGALVHPLILTAFENGQKADALGLDFLGIPVTLLNYSSSVIPI
                     IFSAWLCSILERRLNAWLPSAIKNFFTPLLCLMVITPVTFLLVGPLSTWISELIAAGY
                     LWLYQAVPAFAGAVMGGFWQIFVMFGLHWGLVPLCINNFTVLGYDTMIPLLMPAIMAQ
                     VGAALGVFLCERDAQKKVVAGSAALTSLFGITEPAVYGVNLPRKYPFVIACISGALGA
                     TIIGYAQTKVYSFGLPSIFTFMQTIPSTGIDFTVWASVIGGVIAIGCAFVGTVMLHFI
                     TAKRQPAQGAPQEKTPEVITPPEQGGICSPMTGEIVPLIHVADTTFASGLLGKGIAIL
                     PSVGEVRSPVAGRIASLFATLHAIGIESDDGVEILIHVGIDTVKLDGKFFSAHVNVGD
                     KVNTGDRLISFDIPAIREAGFDLTTPVLISNSDDFTDVLPHGTAQISAGEPLLSIIR"
     gene            1717..3129
                     /gene="bglB"
                     /locus_tag="RN951_004164"
     CDS             1717..3129
                     /gene="bglB"
                     /locus_tag="RN951_004164"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase BglB"
                     /protein_id="HDX2529070.1"
                     /translation="MKAFPETFLWGGATAANQVEGAWQEDGKGISTSDLQPHGVMGKM
                     EPRILGKENIKDVAIDFYHRYPEDIALFAEMGFTCLRISIAWARIFPQGDEVEPNEAG
                     LAFYDRLFDEMAQAGIKPLVTLSHYEMPYGLVKNYGGWANRAVIDHFEHYARTVFTRY
                     QHKVALWLTFNEINMSLHAPFTGVGLAEESGEAEVYQAIHHQLVASARAVKACHSLLP
                     EAKIGNMLLGGLVYPLTCQPQDMLQAMEENRRWMFFGDVQARGQYPGYMQRFFRDHNI
                     TIEMTESDAEDLKHTVDFISFSYYMTGCVSHDESINKNAQGNILNMIPNPHLKSSEWG
                     WQIDPVGLRVLLNTLWDRYQKPLFIVENGLGAKDSVEADGSIQDDYRIAYLNDHLVQV
                     NEAIADGVDIMGYTSWGPIDLVSASHSQMSKRYGFIYVDRDDNGEGSLTRTRKKSFGW
                     YAEVIKTRGLSLKKITIKAP"
     gene            3198..4814
                     /gene="bglH"
                     /locus_tag="RN951_004165"
     CDS             3198..4814
                     /gene="bglH"
                     /locus_tag="RN951_004165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate-specific porin BglH"
                     /protein_id="HDX2529071.1"
                     /translation="MFRRNLITSAILLMAPLAFSAQSLAESLTVEQRLELLEKALRET
                     QSELKKYKDEEKKKYTPATVNRSVSTNDQGYAANPFPTSSAAKPDAVLVKNEEKNASE
                     TGSIYSSMTLKDFSKFVKDEIGFSYNGYYRSGWGTASHGSPKSWAIGSLGRFGNEYSG
                     WFDLQLKQRVYNENGKRVDAVVMMDGNVGQQYSTGWFGDNAGGENYMQFSDMYVTTKG
                     FLPFAPEADFWVGKHGAPKIEIQMLDWKTQRTDAAAGVGLENWKVGPGKIDIALVRED
                     VDDYDRSLQNKQQINTNTIDLRYKDIPLWDKATLMVSGRYVTANESASEKDNQDNNGY
                     YDWKDTWMFGTSLTQKFDKGGFNEFSFLVANNSIASNFGRYAGASPFTTFNGRYYGDH
                     TGGTAVRLTSQGEAYIGDHFIVANAIVYSFGNDIYSYETGAHSDFESIRAVVRPAYIW
                     DQYNQTGVELGYFTQQNKDANSNKFNESGYKTTLFHTFKVNTSMLTSRPEIRFYATYI
                     KALENELDGFTFEDNKDDQFAVGAQAEIWW"
     gene            4841..5947
                     /locus_tag="RN951_004166"
     CDS             4841..5947
                     /locus_tag="RN951_004166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001340430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDX2529072.1"
                     /translation="MNIKIAALTLAIASGISAQWAIAADMPASPAPTIPVKQYVTQVN
                     ADNSVTFRYFAPGAKNVSVVVGVPVPDNIHPMTKDEAGVWSWRTPILKGNLYEYFFNV
                     DGVRSIDTGTAMTNPQRQVNSSMILVPGSYLDTRSVAHGDLIAITYHSNALQSERQMY
                     VWTPPGYTGMGEPLPVLYFYHGFGDTGRSAIDQGRIPQIMDNLLAEGKIKPMLVVIPD
                     TETDAKGIIPEDFVPQERRKVFYPLNAKAADRELMNDIIPLISKRFNVRKDADGRALA
                     GLSQGGYQALVSGMNHLESFGWLATFSGVTTTTVPDEGVAARLNDPAAINQQLRNFTV
                     VVGDKDVVTGKDIAGLKTELEQKKLTLITRNIRV"
     gene            6024..6746
                     /locus_tag="RN951_004167"
     CDS             6024..6746
                     /locus_tag="RN951_004167"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDX2529073.1"
                     /translation="MKLIITEDYQEMSRVAAHHLLGYMSKTRRVNLAITAGSTPKGMY
                     EYLTTLVKGKPWYDNCYFYNFDEIPFRGKEGEGVTITNLRNLFFTPAGIKEENIQKLT
                     IDNYREHDQKLAREGGLDLVVLGLGADGHFCGNLPNTTHFHEQTVEFPIQGEMVDIVA
                     HGELGGDFSLVPDSYVTMGPKSIMAAKNLLIIVSGAGKAQALKNVLQGPVTEDVPASV
                     LQLHPSLMVIADKAAAAELALG"
     gene            complement(6808..>7137)
                     /locus_tag="RN951_004168"
     CDS             complement(6808..>7137)
                     /locus_tag="RN951_004168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CbrC family protein"
                     /protein_id="HDX2529074.1"
                     /translation="DEEDEFAGIKNTYPDEMLKELVERTPGYHGWQQEFWLAHCGDFC
                     VFIGYVGWNDIKDRLDEFANLEEDCENFGIRNSDLAKCLQKGGHCQGYLFRCLHCGKL
                     RLWGDFS"
BASE COUNT         1837 a         1623 c         1829 g         1848 t
ORIGIN      
        1 gtggtcatag gtaaccatgt ggccgatgtc ttcctggcgg ttaacagtgt ggcaggcctt
       61 gacgaaaaag cgcaacaggc accggaaaat gatgataaag gtaatctgct aaaccgcttt
      121 gtttatgtta tttcaggtat ttttacgcct ctgatcggtt tgatggcggc aaccgggatc
      181 ttgaaaggta tgctggctct ggcgctcact tttcagtgga cgaccgaaca aagtggtact
      241 tatttaattt tattcagcgc cagtgatgcc ttgttttggt tcttcccgat aatcctggga
      301 tacaccgcgg ggaaacgctt cggcggtaat ccatttactg ccatggtgat tggtggagcg
      361 ttagtgcatc cattaattct gactgctttc gagaacgggc aaaaagcgga tgcgctgggg
      421 ctggatttcc tgggtattcc ggtcacattg ttgaattact cgtcatcggt tattcccatt
      481 attttttctg cctggttgtg cagcattctg gaacgccgac ttaatgcgtg gttaccgtcg
      541 gcaatcaaaa atttcttcac accattgcta tgtctgatgg ttatcacacc cgtcaccttt
      601 ctgctggtgg ggccgctatc aacctggata agcgaactga ttgccgccgg ttatctctgg
      661 ctttatcagg cggttcctgc atttgcgggc gcggtaatgg gcggcttctg gcaaatcttc
      721 gtcatgttcg gactgcactg gggcctggtg ccgctgtgta tcaataactt caccgtgctg
      781 ggctacgaca ccatgatccc gctgttaatg cccgccatta tggcgcaggt cggggcggcg
      841 ctcggcgtct tcctctgcga acgcgatgcg cagaaaaaag tggtggcggg atcagcggcg
      901 ttgacgagtc tgtttggtat caccgaacca gcggtatatg gcgtcaacct gccgcgtaag
      961 tacccctttg ttatcgcctg tatcagtggg gctttggggg ccaccattat tggctacgcg
     1021 caaacgaaag tctactcctt tggtttgcca agtattttca ccttcatgca aaccatcccg
     1081 tcaacgggaa ttgatttcac cgtctgggcc agcgttattg gcggtgtcat tgccatcggt
     1141 tgcgcatttg tcggtacggt gatgcttcat ttcatcaccg ctaaacgtca gccagcgcag
     1201 ggtgccccgc aagagaaaac accagaggtt attacaccac ctgagcaggg cggtatctgt
     1261 tcaccgatga cgggagagat tgtgccgctc attcacgtcg ctgataccac gtttgccagt
     1321 ggcctgttgg gtaaaggtat tgccattctg ccctcggttg gtgaagtgcg ttctccggtt
     1381 gcgggtcgaa ttgcttcgtt gttcgccaca ttacacgcca ttggcattga gtcagatgat
     1441 ggtgtggaga tcctgattca tgtcggtatc gacaccgtaa aactggacgg caaattcttt
     1501 tccgctcacg tcaacgtggg tgacaaggtc aatacaggcg atcggctgat ttcttttgat
     1561 atccctgcta ttcgcgaggc cggatttgat ctgacgacgc cggtattaat cagtaatagc
     1621 gatgatttta cggacgtatt accccacggc acggcgcaga taagcgcagg tgaaccgctg
     1681 ttatccatca ttcgctaacg ataaaaggag ttaattatga aagcatttcc agaaacattt
     1741 ctttggggtg gcgcaacagc tgccaatcag gtggaaggtg cctggcagga agatggcaaa
     1801 gggatctcga cctcagattt acagcctcat ggcgtaatgg gaaaaatgga accgcgcatc
     1861 ctggggaaag agaatatcaa agatgtcgcc atcgattttt atcaccgtta cccggaagat
     1921 atcgcgttat ttgccgagat gggcttcacc tgtctgcgta tttccattgc ctgggcgcga
     1981 attttccctc agggcgacga agtcgaaccg aatgaagcgg ggttagcgtt ttacgatcgg
     2041 ctgtttgatg aaatggcgca ggcggggatc aagccgctgg taacgttatc ccattacgaa
     2101 atgccatatg ggctggtgaa aaactacggc ggttgggcta atcgagcggt catcgatcac
     2161 ttcgagcatt acgcccgcac ggtctttact cgctaccaac ataaagtggc gttatggctg
     2221 acgtttaatg aaatcaacat gtcgttacac gcgccattca cgggcgtggg gctggcagaa
     2281 gagagtggcg aggcggaagt ttatcaggct atccaccatc aactggttgc cagtgcgcgg
     2341 gcagttaaag cctgtcatag cctgctcccc gaagcgaaaa tcggcaatat gcttctcggt
     2401 gggctggttt accccctcac ctgccagcca caggatatgt tgcaggccat ggaagagaac
     2461 cggcgctgga tgttctttgg tgatgttcag gcgcgtggcc agtatcccgg ctatatgcag
     2521 cgtttcttcc gcgaccacaa tatcaccatt gagatgactg aaagtgacgc agaagattta
     2581 aaacataccg tcgatttcat ctcttttagt tattacatga ctggttgtgt ttcccacgac
     2641 gaaagcatta ataaaaatgc gcagggcaac atactgaata tgatccccaa tccgcatctg
     2701 aaaagttcag agtgggggtg gcaaattgat ccggttggat tacgggttct gttaaatacg
     2761 ctttgggatc gttatcaaaa accgttattt attgtcgaga acggattagg cgcaaaagac
     2821 agcgttgaag cggatggttc gatacaggac gattatcgaa ttgcctattt aaacgatcac
     2881 ctggtacagg taaatgaagc gattgccgat ggtgtggata ttatggggta caccagttgg
     2941 gggccaattg atttagtcag tgcatctcat tcacaaatgt ctaagcgcta cggctttatt
     3001 tatgtggatc gtgatgataa tggcgaagga agcctcacaa gaacacgcaa gaaaagcttc
     3061 ggatggtatg cagaggtgat caagacgcgg gggctgtcat taaaaaaaat aaccattaaa
     3121 gcaccttaat tatcgtcgca ttcagaacag tctggatgcg atgcgttaat tctttctttg
     3181 caccataaag ggatattatg tttagacgaa atcttattac ctctgccatc ttattaatgg
     3241 caccgttagc cttttctgca caatcattgg ctgaatcatt aacggtggaa caacgccttg
     3301 agttattaga aaaggcgtta agagaaacgc aaagcgaact caaaaagtat aaagatgaag
     3361 agaagaaaaa gtatacgcca gcgacggtga atcgtagcgt aagtacgaat gatcaagggt
     3421 atgccgccaa tccgttcccg accagtagtg ccgcaaaacc tgatgctgta ctggtcaaaa
     3481 atgaagagaa aaatgccagt gagacaggct cgatttattc ttccatgact ctgaaagatt
     3541 tcagtaaatt tgtgaaagat gaaattggct ttagttacaa cggctattac cgttctggtt
     3601 gggggaccgc ctctcatggt tcacctaaat catgggcgat tggttctctg ggccgctttg
     3661 gtaacgaata ctccggctgg tttgatttgc agttaaaaca acgtgtctac aacgaaaacg
     3721 gcaaacgggt tgatgccgtt gtgatgatgg atggtaacgt tggtcagcag tactctaccg
     3781 gctggtttgg cgataacgcc ggtggcgaga actatatgca gttctccgat atgtacgtta
     3841 ccaccaaagg tttcctgccc tttgcgccag aggctgattt ctgggtgggt aaacacggtg
     3901 cgccgaaaat tgaaatccag atgcttgact ggaaaacgca gcgtactgat gccgcagcgg
     3961 gtgtaggtct ggaaaactgg aaagtcggtc cgggtaaaat tgatatcgcg ctggttcgcg
     4021 aagatgtcga tgattacgat cgcagcctgc aaaacaaaca gcagattaat accaatacca
     4081 ttgatttacg ctataaagat atcccgttat gggataaagc caccttaatg gtaagtggtc
     4141 gttatgtcac ggcaaacgaa agcgcatcgg aaaaagataa tcaggataat aacgggtatt
     4201 atgactggaa agatacctgg atgtttggca catctttaac gcagaaattt gataaaggtg
     4261 gcttcaacga attctccttc ctggtcgcga ataactctat cgccagtaac tttggccgtt
     4321 atgctggcgc aagtccattt accaccttta atggtcgtta ttatggtgat cacaccggcg
     4381 gaacagcggt acgtctgact tcgcagggcg aagcctatat tggcgatcat ttcattgtag
     4441 ctaacgcgat tgtttactcc ttcggtaacg atatatatag ctacgaaaca ggcgcccact
     4501 ctgatttcga atctattcgt gcggttgttc gcccggccta tatttgggac caatataacc
     4561 agacaggtgt tgaactgggc tatttcaccc agcaaaacaa agatgcgaat agtaataaat
     4621 ttaatgagtc tggttataaa accacgctct tccatacctt taaagtcaat accagtatgt
     4681 tgacctcgcg tccggaaatt cgtttctacg ccacgtatat caaagccctg gaaaacgaac
     4741 tggatggctt cacctttgaa gacaataaag acgaccagtt tgctgtcggt gcccaggctg
     4801 aaatctggtg gtaatggaac ttaatgaaag gaatattacg atgaatataa aaattgctgc
     4861 tttaacgctg gctattgcca gcggtatttc tgctcagtgg gccatagcag cggatatgcc
     4921 agccagcccg gcacccacta tcccggtgaa acagtatgtg actcaggtca atgccgataa
     4981 cagcgtgacc tttcgctact ttgcccctgg ggcaaaaaat gtctctgtag tggtgggtgt
     5041 tccggttccg gacaatattc acccgatgac caaagacgaa gcaggagtct ggtcgtggcg
     5101 cacacctatc ctgaaaggca acctgtacga gtattttttc aatgttgatg gtgtacgcag
     5161 cattgataca ggcaccgcaa tgactaatcc tcagcgccag gttaactcca gtatgattct
     5221 ggtgccaggc agttatctgg atacgcgttc tgttgcgcat ggtgatttga tcgccataac
     5281 ttaccactcc aacgcattgc aatctgaacg tcagatgtat gtctggaccc cgccaggata
     5341 caccggcatg ggcgagcctt tgccagtgct ctatttctat cacggctttg gtgataccgg
     5401 acgttccgct atcgatcagg ggcgtatccc gcaaatcatg gataacctgc ttgctgaagg
     5461 gaaaattaaa ccgatgctgg tggtgatccc ggatacagaa accgatgcga agggcattat
     5521 tcccgaagat ttcgtgcctc aggaaagacg taaagtcttt tatccgctga atgctaaagc
     5581 ggcagatcgc gaactgatga acgatattat cccgctgatt agcaagcgtt ttaatgtccg
     5641 taaagatgcc gatggccgcg cgctggcagg gctttcacaa ggcgggtacc aggcgctggt
     5701 ttccggaatg aatcatctgg aaagctttgg ctggctggcc acattcagtg gtgttaccac
     5761 gacaaccgta ccggatgaag gtgtcgcggc ccgactgaac gatccggcag ctatcaacca
     5821 gcaactacgt aattttactg tggttgtggg ggataaagat gtcgtaaccg gcaaggatat
     5881 cgccgggctg aaaactgagc ttgagcagaa aaaattaact ttgattacca ggaatatccg
     5941 ggtctgaacc atgaaatgga tgtctggcga ccagcctatg cagcctttgt acagaaatta
     6001 tttaaataaa ataaggcatt aagatgaaat taatcattac cgaagattac caggaaatga
     6061 gccgtgtcgc ggcacaccat ctgcttggtt atatgtcgaa gacgcgtcgt gttaacctgg
     6121 caattaccgc cggtagcacg cccaaaggca tgtatgaata cctcaccacc ctggttaaag
     6181 gtaagccctg gtacgataac tgctatttct ataattttga tgaaattcca tttcgcggca
     6241 aagagggaga aggcgtaacg attaccaatc tgcgtaatct gtttttcacc cctgcgggga
     6301 tcaaagaaga gaatatccag aagctcacta ttgataacta ccgcgagcat gatcagaaac
     6361 tggcgcgtga aggcggactg gatttggtgg tgctgggatt aggtgcagat ggtcattttt
     6421 gtggcaattt gccgaatacg acccatttcc atgagcaaac cgtggagttc ccgatccagg
     6481 gagagatggt tgatattgtg gcgcatggcg agttgggcgg cgacttttcg ttagtgcctg
     6541 acagctacgt gacgatgggg ccgaaaagca tcatggcggc gaaaaacttg ctgataattg
     6601 tcagcggcgc gggtaaagcg caggcactga aaaatgttct gcaaggtccg gttaccgaag
     6661 atgttccagc ttccgtgttg cagctgcatc cttcgctgat ggtaatcgct gataaagccg
     6721 ctgccgcaga attagcactc ggttaagctt aagaaataag gccggatgtg tgaattacgc
     6781 tccggcctgt tctcattatt taaataacta cgaaaaatca ccccacagtc tcagcttgcc
     6841 gcagtggaga cagcggaaga gataaccctg acaatgacca cccttttgca ggcatttagc
     6901 tagatcagaa tttctaatac cgaaattctc acaatcttct tcaaggttgg caaattcatc
     6961 gaggcgatct tttatatcat tccagcccac atagccgata aaaacacaga aatcgccaca
     7021 atgcgcgagc cagaattcct gctgccatcc atgataacct ggcgtgcgtt caaccaactc
     7081 tttcagcatt tcatcaggat atgtgttctt aataccggca aattcgtcct cttcatc
//
LOCUS       DAPOAV010000149         7054 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.150, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000149 DAPOAV010000000
VERSION     DAPOAV010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7054
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.150"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            574..1563
                     /gene="araF"
                     /locus_tag="RN951_004169"
     CDS             574..1563
                     /gene="araF"
                     /locus_tag="RN951_004169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter substrate-binding
                     protein AraF"
                     /protein_id="HDX2529075.1"
                     /translation="MHKFTKALAAIGLAAVMSQSAMAENLKLGFLVKQPEEPWFQTEW
                     KFADKAGKDLGFEVIKIAVPDGEKTLNAIDSLAASGAKGFVICTPDPKLGSAIVAKAR
                     GYDMKVIAVDDQFVNAKGKPMDTVPLVMMAATKIGERQGQELYKEMQKRGWDVKESAV
                     MAITANELDTARRRTTGSMDALKAAGFPEKQIYQVPTKSNDIPGAFDAANSMLVQHPE
                     VKHWLIVGMNDSTVLGGVRATEGQGFKAADIIGIGINGVDAVSELSKAQATGFYGSLL
                     PSPDVHGYKSSEMLYNWVAKDVEPSKFTEVTDVVLITRDNFKEELEKKGLGGK"
     gene            1633..3147
                     /gene="araG"
                     /locus_tag="RN951_004170"
     CDS             1633..3147
                     /gene="araG"
                     /locus_tag="RN951_004170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter ATP binding protein
                     AraG"
                     /protein_id="HDX2529076.1"
                     /translation="MQQSTPYLSFRGIGKTFPGVKALTDISFDCYAGQVHALMGENGA
                     GKSTLLKILSGNYAPTTGSVVINGQEMSFSDTTAALNAGVAIIYQELHLVPEMTVAEN
                     IYLGQLPHKGGIVNRSLLNYEAGLQLKHLGMDIDPDTPLKYLSIGQWQMVEIAKALAR
                     NAKIIAFDEPTSSLSAREIDNLFRVIRELRKEGRVILYVSHRMEEIFALSDAITVFKD
                     GRYVKTFTDMQQVDHDALVQAMVGRDIGDIYGWQPRSYGEERLRLDAVKAPGVRTPIS
                     LAVRSGEIVGLFGLVGAGRSELMKGMFGGTQITAGQVYIDQQPIDIRKPSHAIAAGMM
                     LCPEDRKAEGIIPVHSVRDNINISARRKHVLGGCVINNGWEENNADHHIRSLNIKTPG
                     AEQLIMNLSGGNQQKAILGRWLSEEMKVILLDEPTRGIDVGAKHEIYNVIYALAAQGV
                     AVLFASSDLPEVLGVADRIVVMREGEIAGELLHEQADERQALSLAMPKVSQAVA"
     gene            3162..4148
                     /gene="araH"
                     /locus_tag="RN951_004171"
     CDS             3162..4148
                     /gene="araH"
                     /locus_tag="RN951_004171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter permease AraH"
                     /protein_id="HDX2529077.1"
                     /translation="MSSVSTSGSGAPKSSFSFGRIWDQYGMLVVFAVLFIACAIFVPN
                     FATFINMKGLGLAISMSGMVACGMLFCLASGDFDLSVASVIACAGVTTAVVINLTESL
                     WIGVAAGLLLGVLCGLVNGFVIAKLKINALITTLATMQIVRGLAYIISDGKAVGIEDE
                     SFFALGYANWFGLPAPIWLTVACLIIFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVV
                     RTKIIIFVLSGLVSAIAGIILASRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKI
                     SYVVAGILILGTVENAMNLLNISPFAQYVVRGLILLAAVIFDRYKQKAKRTV"
     gene            4315..5115
                     /gene="otsB"
                     /locus_tag="RN951_004172"
     CDS             4315..5115
                     /gene="otsB"
                     /locus_tag="RN951_004172"
                     /EC_number="3.1.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose-phosphatase"
                     /protein_id="HDX2529078.1"
                     /translation="MTEPLTETPELSAKYAWFFDLDGTLAEIKPHPDQVVVPDNILQG
                     LQLLATASDGALALISGRSMVELDALAKPYRFPLAGVHGAERRDINGKTHIVHLPDAI
                     ARDISVQLHTVIAQYPGAELEAKGMAFALHYRQAPQHEDALMTLAQRITQIWPQMALQ
                     QGKCVVEIKPRGTSKGEAIAAFMQEAPFIGRTPVFLGDDLTDESGFAVVNRLGGMSVK
                     IGTGATQASWRLAGVPDVWSWLEMITTALQQKRENNRSDDYESFSRSI"
     gene            5090..6514
                     /gene="otsA"
                     /locus_tag="RN951_004173"
     CDS             5090..6514
                     /gene="otsA"
                     /locus_tag="RN951_004173"
                     /EC_number="2.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalose-phosphate synthase"
                     /protein_id="HDX2529079.1"
                     /translation="MSRLVVVSNRIAPPDEHAASAGGLAVGILGALKAAGGLWFGWSG
                     ETGNEDQPLKKVKKGNITWASFNLSEQDLDEYYNQFSNAVLWPAFHYRLDLVQFQRPA
                     WDGYLRVNALLADKLLPLLQDDDIIWIHDYHLLPFAHELRKRGVNNRIGFFLHIPFPT
                     PEIFNALPTYDTLLEQLCDYDLLGFQTENDRLAFLDCLSNLTRVTTRSAKSHTAWGKA
                     FRTEVYPIGIEPKEIAKQAAGPLPPKLAQLKAELKNVQNIFSVERLDYSKGLPERFLA
                     YEALLEKYPQHHGKIRYTQIAPTSRGDVQAYQDIRHQLENEAGRINGKYGQLGWTPLY
                     YLNQHFDRKLLMKIFRYSDVGLVTPLRDGMNLVAKEYVAAQDPANPGVLVLSQFAGAA
                     NELTSALIVNPYDRDEVAAALDRALTMSLAERISRHAEMLDVIVKNDINHWQECFISD
                     LKQIVPRSAESQQRDKVATFPKLA"
     gene            complement(6521..6949)
                     /gene="uspC"
                     /locus_tag="RN951_004174"
     CDS             complement(6521..6949)
                     /gene="uspC"
                     /locus_tag="RN951_004174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspC"
                     /protein_id="HDX2529080.1"
                     /translation="MSYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPE
                     MYNQLAAPMLEDLRSVMQEETQSFLDKLIQDAGYPVDKTFIAYGELSEHILEVCHKHH
                     FDLVICGNHNHSFFSRASCSAKRVIASSEVDVLLVPLTGD"
BASE COUNT         1787 a         1639 c         1828 g         1800 t
ORIGIN      
        1 atgaatttta atgatagtgc tttttgtatc ttgttgatat taatcaatga atttgaattc
       61 atgatgaagt gatgatttta taaaacgttt tttcattttt gcgagatggc tctcattata
      121 cgtgttctgt taattaatga gcacagtgat aattaatgac gaaatgaatg acgtgcattt
      181 tccacatctt tgagttgcgg ttattacacc atttcaaaaa ctcaacgcca ggtaatgcgg
      241 cctattgact ggttaaaaag aagacatccc gcatgggtac caaagacaac aaggatttcc
      301 aggctaatct tatggattaa tctgctgtgc attcgacaat ttgtctgaca aattggcttt
      361 cccttatgtc ttttcccgct aaatttatgc acgttctcac tgtaattctg cgatgtgata
      421 ttgctctcct atggagaatt aatttctcgc taaaactatg tcaacacagt cacttatctt
      481 ttagttaaaa ggtaatgctt tgttttccga ttaatttaac gaatgtcatt cgtttttgcc
      541 ctacacaaaa cgacactaaa gctggagaga accatgcaca aatttactaa agccctggca
      601 gccattggtc tggcagccgt tatgtcacaa tccgctatgg cggagaacct gaagctcggt
      661 tttctggtga agcaaccgga agagccgtgg ttccagaccg aatggaagtt tgccgataaa
      721 gccgggaagg atttagggtt tgaggttatt aagattgccg tgccggatgg cgaaaaaaca
      781 ttgaacgcga tcgacagcct ggctgccagt ggcgcaaaag gtttcgttat ttgtactccg
      841 gaccccaaac tcggctctgc catcgtcgcg aaagcgcgtg gctacgatat gaaagtcatt
      901 gccgtggatg accagtttgt taacgccaaa ggtaagccaa tggataccgt tccgctggtg
      961 atgatggcgg cgactaaaat tggcgaacgt cagggccagg aactgtataa agagatgcag
     1021 aaacgtggct gggatgtcaa agaaagcgcg gtgatggcga ttaccgccaa cgaactggat
     1081 accgcccgcc gccgtactac gggatctatg gatgcgctga aagcggccgg attcccggaa
     1141 aaacaaattt atcaggtacc taccaaatct aacgacatcc cgggggcatt tgacgctgcc
     1201 aactcaatgc tggttcaaca tccggaagtt aaacattggc tgatcgtcgg tatgaacgac
     1261 agcaccgtgc tgggcggcgt acgcgcgacg gaaggtcagg gctttaaagc ggccgatatc
     1321 atcggcattg gcattaacgg tgtggatgcg gtgagcgaac tgtctaaagc acaggcaacc
     1381 ggcttctacg gttccctgct gccaagcccg gacgtacatg gctataaatc cagcgaaatg
     1441 ctttacaact gggtagcaaa agacgttgaa ccgtcaaaat ttaccgaagt taccgacgtg
     1501 gtactgatca cgcgtgacaa ctttaaagaa gaactggaga aaaaaggttt aggcggtaag
     1561 taatttgccg gaaaaattcc cctctgcatg atgcagaggg ggtgtgaacg accagtgatt
     1621 cacggagacg ttatgcaaca gtctaccccg tatctctcat ttcgcggcat cggtaaaacg
     1681 tttcccggcg ttaaggcgct gacggatatt agttttgact gctatgccgg tcaggttcat
     1741 gcgttgatgg gtgaaaatgg cgcaggaaaa tcaactctct taaaaatcct cagcggcaac
     1801 tatgcgccaa ccacgggttc tgtagtgatt aatgggcagg aaatgtcctt ttccgacacg
     1861 accgcagcac ttaacgcggg cgtggcgatt atttaccagg aactgcatct cgtgccggaa
     1921 atgaccgtcg cggaaaacat ctatctcggc cagctgccgc ataaaggcgg cattgtgaat
     1981 cgctcattgc tgaattatga ggcgggttta caacttaaac atcttggtat ggatattgac
     2041 ccggacacgc cgctgaaata tctctccatt ggtcagtggc agatggttga aatcgccaaa
     2101 gcgctggcgc gtaacgccaa aattatcgcc tttgatgagc caaccagctc cctctctgcc
     2161 cgtgaaatcg acaatctttt ccgcgttatt cgtgaactgc gaaaagaggg gcgggtaatc
     2221 ttatacgttt ctcaccgtat ggaagaaata tttgccctca gcgatgccat tactgtcttt
     2281 aaagatggac gttatgtcaa aacctttacc gatatgcagc aggttgacca cgacgcgctg
     2341 gtgcaggcga tggtcgggcg cgacattggc gatatctacg gctggcaacc gcgtagttat
     2401 ggcgaggagc gcctacgtct tgatgctgtg aaagcaccag gcgtgcgtac gccaataagt
     2461 ctggcggttc gcagtggtga aattgttggg ctgtttggtc tggtaggggc ggggcgtagc
     2521 gaattaatga aaggcatgtt tggcgggacg caaatcaccg ccggtcaggt ttatatcgac
     2581 caacagccga tcgatattcg taaaccgagc cacgccattg ccgcaggcat gatgctctgc
     2641 ccggaagatc gcaaagcgga aggcattatt cccgtgcact ccgttcgcga caatatcaac
     2701 atcagtgcca gacgtaaaca tgtgctcggc ggttgtgtaa tcaacaacgg ttgggaagaa
     2761 aacaatgccg atcaccacat tcgttcgctc aacatcaaaa cgccgggcgc ggagcaactg
     2821 atcatgaatc tctcaggcgg aaatcagcaa aaagccattc tgggccgctg gttatcggaa
     2881 gagatgaagg tcattttgct ggatgaacct acgcgcggca ttgatgttgg cgctaagcac
     2941 gaaatatata acgtaattta tgcgctggcg gcgcagggcg tggcggtgct gtttgcctcc
     3001 agcgacttac ctgaagtcct cggcgttgcc gaccggattg tggtgatgcg ggaaggtgaa
     3061 atcgccggtg aattgttaca cgagcaggca gatgagcgtc aggcactgag ccttgcgatg
     3121 cctaaagtca gccaggctgt tgcctgagta aggagagtat gatgtcttct gtttctacat
     3181 cggggtctgg cgcacctaag tcgtcattca gcttcgggcg tatctgggat cagtacggca
     3241 tgctggtggt gtttgcggtg ctctttatcg cctgtgccat ttttgtccca aattttgcca
     3301 ccttcattaa tatgaaaggg ttgggcctgg caatttccat gtcggggatg gtggcttgtg
     3361 gcatgttgtt ctgcctcgct tccggtgact ttgacctttc tgtcgcctcc gtaattgcct
     3421 gtgcgggtgt caccacggcg gtggttatta acctgactga aagcctgtgg attggcgtgg
     3481 cagcggggtt gttgctgggc gttctctgtg gcctggtcaa tggctttgtt atcgccaaac
     3541 tgaaaataaa tgctctgatc acgacattgg caacgatgca gattgttcga ggtctggcgt
     3601 acatcatttc agacggtaaa gcggtcggta tcgaagatga aagcttcttt gcccttggtt
     3661 acgccaactg gttcggtctg cctgcgccaa tctggctcac cgtcgcgtgt ctgattatct
     3721 ttggtttgct gctgaataaa accacctttg gtcgtaacac cctggcgatt ggcgggaacg
     3781 aagaggccgc gcgtctggcg ggtgtaccgg ttgttcgcac caaaattatt atctttgttc
     3841 tctcaggcct ggtatcagcg atagccggaa ttattctggc ttcacgtatg accagtgggc
     3901 agccaatgac gtcgattggt tatgagctga ttgttatctc cgcctgcgtt ttaggtggcg
     3961 tttctctgaa aggtggcatc ggaaaaatct catatgtggt ggcgggtatc ttaattttag
     4021 gcaccgtgga aaacgccatg aacctgctta atatttctcc tttcgcgcag tacgtggttc
     4081 gcggcttaat cctgctggca gcggtgatct tcgaccgtta caagcaaaaa gcgaaacgca
     4141 ctgtctgatg cttttttctg caacaattta gcgttttttc ccaccatagc caaccgccat
     4201 aacggttggc tgttcttcgt tgcaaatggc gacccccgtc acactgtcta tacttacatg
     4261 tctataaagc gcgttctgcg caacacaata agaaaagaga aggaggagaa ccgggtgaca
     4321 gaaccgttaa ccgaaacccc tgaactatcc gcgaaatatg cctggttttt tgatcttgat
     4381 ggaacgctgg cggaaatcaa accgcatccc gatcaggtcg tcgtgcctga caatattctg
     4441 caaggactac agctactggc aaccgcaagt gatggtgcat tggcattgat atcagggcgc
     4501 tcaatggtgg agcttgacgc actggcaaaa ccttatcgct tcccgttagc gggcgtgcat
     4561 ggggcggagc gccgtgacat caatggtaaa acacatatcg ttcatctgcc ggatgcgatt
     4621 gcgcgtgata ttagcgtgca actgcataca gtcatcgctc agtatcccgg cgcggagctg
     4681 gaggcgaaag ggatggcttt tgcgctgcat tatcgtcagg ctccgcagca tgaagacgca
     4741 ttaatgacat tagcgcaacg tattactcag atctggccac aaatggcgtt acagcaggga
     4801 aagtgtgttg tcgagatcaa accgagaggt accagtaaag gtgaggcaat tgcagctttt
     4861 atgcaggaag ctccctttat cgggcgaacg cccgtatttc tgggcgatga tttaaccgat
     4921 gaatctggct tcgcagtcgt taaccgactg ggcggaatgt cagtaaaaat tggcacaggt
     4981 gcaactcagg catcatggcg actggcgggt gtgccggatg tctggagctg gcttgaaatg
     5041 ataaccaccg cattacaaca aaaaagagaa aataacagga gtgatgacta tgagtcgttt
     5101 agtcgtagta tctaaccgga ttgcaccacc agacgagcac gccgccagtg ccggtggcct
     5161 tgccgttggc atactggggg cactgaaagc cgcaggcgga ctgtggtttg gctggagtgg
     5221 tgaaacaggg aatgaggatc agccgctaaa aaaggtgaaa aaaggtaaca ttacgtgggc
     5281 ctcttttaac ctcagcgaac aggaccttga cgaatactac aaccaattct ccaatgccgt
     5341 tctctggccc gcttttcatt atcggctcga tctggtgcaa tttcagcgtc ctgcctggga
     5401 cggctatcta cgcgtaaatg cgttgctggc agataaatta ctgccgctgt tgcaagacga
     5461 tgacattatc tggatccacg attatcacct gttgccattt gcgcatgaat tacgcaaacg
     5521 gggagtgaat aatcgcattg gtttctttct gcatattcct ttcccgacac cggaaatctt
     5581 caacgcgctg ccgacatatg acaccttgct tgaacagctt tgtgattatg atttgctggg
     5641 tttccagaca gaaaacgatc gtctggcgtt cctggattgt ctttctaacc tgacccgcgt
     5701 cacgacacgt agcgcaaaaa gccatacagc ctggggcaaa gcatttcgaa cagaagtcta
     5761 cccgatcggc attgaaccga aagaaatagc caaacaggct gccgggccac tgccgccaaa
     5821 actggcgcaa cttaaagcgg aactgaaaaa cgtacaaaat atcttttctg tcgaacggct
     5881 ggattattcc aaaggtttgc cagagcgttt tctcgcctat gaagcgttgc tggaaaaata
     5941 tccgcagcat catggtaaaa ttcgttatac ccagattgca ccaacgtcgc gtggtgatgt
     6001 gcaagcctat caggatattc gtcatcagct cgaaaatgaa gctggacgaa ttaatggtaa
     6061 atacgggcaa ttaggctgga cgccgcttta ttatttgaat cagcattttg accgtaaatt
     6121 actgatgaaa atattccgct actctgacgt gggcttagtg acgccactgc gtgacgggat
     6181 gaacctggta gcaaaagagt atgttgctgc tcaggaccca gccaatccgg gcgttcttgt
     6241 tctttcgcaa tttgcgggag cggcaaacga gttaacgtcg gcgttaattg ttaaccccta
     6301 cgatcgtgac gaagttgcag ctgcgctgga tcgtgcattg actatgtcgc tggcggaacg
     6361 tatttcccgt catgcagaaa tgctggacgt tatcgtgaaa aacgatatta accactggca
     6421 ggagtgcttc attagcgacc taaagcagat agttccgcga agcgcggaaa gccagcagcg
     6481 cgataaagtt gctacctttc caaagcttgc gtaggagcgg ttaatctccc gtaagtggaa
     6541 ctaacagcac atcgacctca cttgaggcaa taactctttt cgccgagcag gatgctcgcg
     6601 aaaagaaact gtgattgtga ttaccgcaaa tcaccaaatc gaaatgatgc ttgtgacata
     6661 cttccagaat atgttcgctt aactcaccgt aggcaataaa cgtcttgtca acgggatacc
     6721 ccgcatcctg aattaactta tcaagaaagc tttgcgtttc ttcctgcatc acgctgcgta
     6781 aatcttcaag catcggcgca gctaattgat tgtacatttc cgggtcggaa gcgagagtaa
     6841 ttaaactgat gtgtcccttt actggcctgg cgatagatac cgcttttgcc agcagttgct
     6901 gactttccgg tgtaaccgca acagcgacaa gaatattgct atagctcata acctgttcct
     6961 tattctgtga acttcaggtg acattaaagc tttactccta atggagaaac gacgcaatcc
     7021 caactcggtc aaacaggtaa atattagtct gatt
//
LOCUS       DAPOAV010000150         7023 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.151, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000150 DAPOAV010000000
VERSION     DAPOAV010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7023
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.151"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(145..510)
                     /locus_tag="RN951_004175"
     CDS             complement(145..510)
                     /locus_tag="RN951_004175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000467436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529081.1"
                     /translation="MFGLRKVNRNTHTFETTFQNWKENGEDVALLMPEFSAKWLPIAE
                     ESGSWSGWVLLGEIFPLISSELAGMALMPETERLIGEWLSLSSSPLNLKHPELKYNRL
                     HVGKVFDGVLSPAQPLIRI"
     gene            complement(510..629)
                     /locus_tag="RN951_004176"
                     /pseudo
     CDS             complement(510..629)
                     /locus_tag="RN951_004176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001314987.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion protein"
     gene            complement(642..2252)
                     /locus_tag="RN951_004177"
                     /pseudo
     CDS             complement(642..2252)
                     /locus_tag="RN951_004177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001613747.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2926..3915)
                     /locus_tag="RN951_004178"
     CDS             complement(2926..3915)
                     /locus_tag="RN951_004178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529082.1"
                     /translation="MNMTKNAFQFGIEPVHITDNDNLQVNEGLPTNADPQVYALQLAK
                     TVKAMLNGVLKDAQDNIPFPVEVLPTRNSLPTPIIAHTLADRSVLVPVRGGKRPEVVT
                     APSGTEITVEPIEQAILVSHQTKLWDQKSTTGFTQGTLQQDALNICDNVVRTINSKMV
                     DVLESSKLLKTVELPALTGSLTAKADAIMDALYENTESSFGSEVSDYGIIAHESHLKA
                     LSRLAAKQGFGGEDAIVDMLGTDVAYYNGEDRGVFMMAKRFTALSFGCFRHDGENITV
                     VLSRDGDSQSHDLEILGKVFVVAEAATTIKMGTGSATAVLPVVKRLSFTKEAN"
     gene            complement(3999..4490)
                     /locus_tag="RN951_004179"
     CDS             complement(3999..4490)
                     /locus_tag="RN951_004179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529083.1"
                     /translation="MLFNNNDWKLSVTDINLYENTVSLDGQPYPLSLAIKTLIPGYLS
                     GLPSTSREAMELLEALAEAGVTIGNFFSNDLMTAYGRRQQNKRVEAERIAKEQRIQAD
                     RMREENMTDEEWQKELQRREQVKAERRTYGENLRSATHSAGRSRAAIVADLESGGNWM
                     DSL"
     gene            complement(4791..5519)
                     /locus_tag="RN951_004180"
     CDS             complement(4791..5519)
                     /locus_tag="RN951_004180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HDX2529084.1"
                     /translation="MSQQEISVINLDQLVSMTSVEIAELTGKEHRNVLRDIRNMAEEL
                     NALKTEQCSKLSSHIGVTEDVYLNAQGKQQPLYRLDRKHTFILVAGYSVHLRAKCYDH
                     IQTLERRVLQLEDQKKRAAIQSANRRGVTWGDYCKTYGLPAQKLMTALLQHRGLFRKN
                     PISNEWSVNPKYSDCFRIIKPSDQKFSAGGYNFRFNAKGLEVFGKPEMVDKMRGILIA
                     FTGTDQQKQEHLLKLAQSGKVEGI"
     gene            complement(6443..6949)
                     /locus_tag="RN951_004181"
                     /pseudo
     CDS             complement(6443..6949)
                     /locus_tag="RN951_004181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012540599.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
BASE COUNT         1757 a         1670 c         1624 g         1972 t
ORIGIN      
        1 aatatcaaca agacttctgt aacatgtttt actaaatcca attacaaaat gaatggacca
       61 atataatgat tttttgtcta acgctggagc gtttccgtat tggcagactg tgactttatc
      121 taaccaaaga ttcaattccc ctgttcatat tcttattagt ggttgagcag ggctcaatac
      181 tccatcaaat actttaccta cgtgcaaacg attatatttt agttcaggat gctttagatt
      241 taacggggaa ctggataaac tgagccattc ccctattaac ctttccgttt ctggcattaa
      301 agccatccca gcgagctcag atgaaattaa gggaaatatt tctccaagca atacccatcc
      361 agaccagctg ccactctctt ctgctatcgg taaccattta gcactaaatt cgggcattaa
      421 taatgcaaca tcttcgccat tttctttcca attttgaaaa gtggtttcaa acgtatgagt
      481 gtttcgattt actttcctca gaccgaacat taactttcat ccttctgatc gttttcgaat
      541 ttgctttcat tttcttgctc ctcataaggc tgatgtcgtt gtccttgtcg ttcatcttgc
      601 tcagtcaata cccaacgttg tgctgtaact cattatgaaa actatttaat tccctcatca
      661 ttgataaggt tggacatctc tttcaacatg agagtcattg aagctttcga ccaatttagc
      721 ggaatgatag ggcttggcgc ttcatgcaaa gttcccgact tgtggatata gttatagctt
      781 tcgggaagtg ccatttcagg tacactcctg ccatttgcac caatcatatt ctcgcctgtt
      841 atttgggcca atgatctatt cataaattgc actgagtcat tcaaatactc ttcctttctt
      901 gattctttat aaacaattgc tgctgatttt gcataccatg agtcaaaaaa ccattctgct
      961 tctgttgatg gaatgaagct cttttctctt ttcgcatgtg aattttgatc ggtatcggtt
     1021 ttaatatcat tgaaccaaaa atttgccgac tgataattat ccttctcgta tctttttata
     1081 ccatacggac ctgctagttt tttaactatt tttagaacct gctcttttct tctggtgttt
     1141 atctttgcaa gatttgcagg ataaataaca ttaagtaaag ccgcatcggc ttctctgtaa
     1201 tgtttatctt tttccagata acctggggat tctcccccta aatcaagctg taacgttatt
     1261 ctttcataac ctttatctat gaggtggttc aacctcgttg ttgaaagagg ttcatccagt
     1321 tcattggctt tagcttcgcg tagtaaatca gagacaaaaa cagagtcttt cttcgagagt
     1381 aagttcgaca aacgttccag tccagaggtc accagtgcaa cggaagatgt gtttaatcgg
     1441 gcatcttctt cccatgctcc ggaatcttcc ataacataga aattggcttt atccagataa
     1501 gcaatcagca gcgcaaccga ttttaatcgg tcaccttttt gccaatcttc agcgttaatt
     1561 gtatcagtgt cgattgcttg tataaggaga tcaagataaa gacctaacgc atcattttgt
     1621 ttatggttcc acagctgcgg cttgccttct tcctgcacat ctgccatcac gggggagttg
     1681 ctgtcaaatc ggatatgcac aacattcatt tgcccgggaa ctccatccag tcgtttgggg
     1741 ttgctaatga cgtcctgcat ccgcttaatc tggtcgggcg tagacatata atcccacagg
     1801 gtgagcagaa ccttttttgc ggctacacta tttccctgat ctgatactaa tgccatatag
     1861 ccccataaac tatccctcag ctagacagca tcatagtggg tttctgccgc tgttttgtca
     1921 tcttcgaaag tagaagcaag aataaacgtt ccccagggtt tctccgtcaa cgttaacttt
     1981 cgtgtgtttt ctgttaatgt tagcaatcct tgaatttcgt ctttggtata gtggctcttt
     2041 atttcatttt gtaatttggc tgagtgaatc aaaagacgat aattaggata cttatctgga
     2101 tttaacgata aataactttt atctgttgct gcccccgtgg aattaagaat gttaaataca
     2161 gattcactcg tcacttctgc ccctgtcgcc tggcatgtgc cgcacgaaaa tataccagcg
     2221 agcagaagag ttaatgcaga tttccctttc ataaaatatt ccatcaatcg tttgttaaaa
     2281 gcgtagataa ccacttattt aacaacttga aaataaggtg ttttacctgg gttgttacaa
     2341 aaggattgca ttgcgtaaac gctttttatt tacaacaaaa tggggaagta ttacggcgat
     2401 tgcgaaaagt ctgaagcgat tgaattaaga taatatagaa aatcagatac agcaaaaatg
     2461 gcagattgat caggtgaaga taaattggag cgggcgaagg gagcctacga caaatcgaag
     2521 acaaccagct aacctattgt ttcttaaaga caggtgaatc cagttggttg tagtgatagt
     2581 cacacattta gagatagaag gtcaagactt gaagcacgta atattccctc taaaggaata
     2641 gaactcacgg tctgactacc cggccctttt ggtctggctc aggtcaggct atgggggctt
     2701 ttggctcgct ctttatatta gatgaggtct cacatttttc agtcaaaact catcgtctaa
     2761 tagcccatag ccagaccacc agtcccagct ttagcaggaa gaccacgaga tagactttgt
     2821 gtaggtccat ttggccctcc tactttctgt attcacgaac tagattacta gtacaaaata
     2881 aaggccagac atccagttcg gaagtctgac caatagtcgt tattgttagt tagcttcttt
     2941 agtgaagctc aggcgtttga ctacaggcag gacagcagta gccgagccag tacccatctt
     3001 gatggtcgta gcagcttcag ctacaacaaa caccttgccg agaatctcaa ggtcgtgaga
     3061 ctgggagtct ccatcacgtg aaaggaccac agtaatgttc tcgccatcgt gacggaagca
     3121 accgaagctc agagccgtaa aacgcttagc catcatgaac acgccacggt cttcaccgtt
     3181 gtaataggcg acgtcagtcc ccagcatatc gacgatagcg tcttcaccac cgaagccctg
     3241 cttagcagcc agacgggaga gagccttgag gtgtgactca tgggcgataa tgccgtagtc
     3301 agaaacctca gaaccgaaag aagactccgt gttctcgtac agggcatcca tgatagcgtc
     3361 agccttagcg gtcaggctac cagtcagggc cggaagttct acggtcttca gcagctttga
     3421 ggactccagc acgtcaacca tcttagagtt aatggtacga accacgttat cgcagatgtt
     3481 cagtgcgtcc tgctggagcg tcccctgagt gaaaccagtg gtcgacttct ggtcccaaag
     3541 ctttgtttgg tgagacacga ggatcgcctg ttcaatcggc tcaacggtga tttcagtgcc
     3601 agacggagcg gtcacaactt caggtcgctt accaccacgg acagggacca gcacagagcg
     3661 gtcagccaga gtgtgagcaa tgattggagt cggtaagctg ttacgggtcg gcaggacttc
     3721 tacagggaac gggatgttat cttgagcgtc tttaagtaca ccgttcagca tagccttaac
     3781 agtcttagct aactggaggg catagacctg agggtcggcg ttagtcggaa ggccctcatt
     3841 aacctgaagg ttgtcgttgt cggtgatatg aacaggctca atgccaaact ggaaagcgtt
     3901 tttagtcata ttcattataa ttaatctcct tgagtcaaat acttgaagtc cctaacaggc
     3961 agtcagggac cgtgtgttct cagatgaggg acgcttgctt acaagctgtc catccagtta
     4021 ccgcctgact caaggtcagc gacgatagcg gcacgtgagc gaccagcgga atgagtagcg
     4081 ctgcggaggt tctcaccata ggtccggcgt tcagctttga cctgctcgcg acgctgtagc
     4141 tctttctgcc actcttcgtc ggtcatgttc tcttcacgca tacggtccgc ctgaatgcgc
     4201 tgctctttag cgatacgctc ggcttcgact cgcttgttct gctggcggcg accataggcg
     4261 gtcatcaggt cattactgaa gaagttacca atggtcacgc cagcttcagc cagagcctct
     4321 aacagctcca ttgcctcgcg gctggtagac ggcaggcctg acaagtagcc cggaatgagg
     4381 gtcttgatag cgagcgacaa cgggtatggc tgaccgtcca gactcacagt attctcgtag
     4441 agattgatgt cggtgactga tagtttccag tcgttgttgt tgaataacat aagttggtac
     4501 tcctcttgag ggttgagact atcggtcgac cacaggcgtg tttagtcctg cggcgtctcc
     4561 ccgcatcggt catctcaaaa ggtttaaaat taggtattga gtaggtgagc tactaacggt
     4621 taggcgacag tttcatagcg accagttggg ctattagctc gtctcgtgat tggtgctggc
     4681 gggtcccatc ttccgggtct agaccaagct ccttcaggat gacctcagtc cggtagccac
     4741 ggtaacggag agtcatgcgc ccctcaggtg tgcgcgggtc aatcatcatc ttagattccc
     4801 tccaccttac cggattgtgc cagcttcagg aggtgctctt gcttctgctg gtcggtgcca
     4861 gtgaatgcaa taaggatgcc tcgcatcttg tcaaccatct caggcttacc gaagacctcc
     4921 agccccttag cgttgaaccg gaagttatac ccacctgctg agaacttctg gtctgacggc
     4981 ttaatgatac gaaagcagtc ggaatacttc ggatttacag accactcgtt actgattggg
     5041 ttcttacgaa agaggccacg atgctggaga agtgcggtca ttagcttctg agcgggcaga
     5101 ccataggttt tgcagtagtc gccccaagtc acgcctcggc ggttagcgga ctgaatggct
     5161 gctcgcttct tctggtcttc cagttgaagg actcgacgct ctaacgtctg aatatggtcg
     5221 taacacttgg cgcggaggtg aacggaatag ccagcgacca gaatgaaagt atgcttacgg
     5281 tcgagacgat acagcggctg ctgtttcccc tgcgcgttta gatagacatc ttcagtcacc
     5341 ccgatatgac tgctcagttt tgagcactgc tcagttttga gcgcgttaag ctcctcagcc
     5401 atattgcgaa tatcacgcag gacatttcgg tgctccttgc ctgtcagctc agcaatttca
     5461 actgaggtca tggagacaag ctggtcgagg ttaatgacgc tgatttcttg ttgggacatt
     5521 tacgtgtact ccttttgttt gcaccctgaa gtcgcacccc actgacctac tcaagccccc
     5581 acgtaaaggg agaccagcag gcaacaggac gcaaacagaa tgacttgagg taattggggt
     5641 tagtggtctg cgatgaccat agagatgaag gttcgacagc atgtccgagc gtgtgtggtg
     5701 atagacttaa gtcacgagac caaagaacac acaggctgac cagaggctgt cttgccttag
     5761 gctggtggct agcaagctag cgtggaccac ggtttctcgc ttgccgtctc tcaggaggtc
     5821 agaggcgaga tatggtccct atagtgatag tttagtcaaa caggaatgaa cttcggagaa
     5881 cttgacgcga aagtgttcag tacttccagt tagacccgaa gcatggagac cacatcatag
     5941 cgaccgtagt atacttcggg ctgacaggac tggaggctgg acttaaagtt cttcttattg
     6001 gaattgtgat aacacaatcc ataacaagat gaactcatgg tctcctcaag cctgctggtc
     6061 aggctcaaag ctccaacctc agacaccact ggtctaacct ctttgagttt ccgcctgtcc
     6121 acaaatggat ggcagacctc agcaatgatg tcttggttct tcagttatcc gcgcagcgat
     6181 tatcacagag ccaacttaaa gtcggatgtg gtctactgct ccccgcctgt caaaagggaa
     6241 gatagcttac gttaaaagga atggtctcag gccaaggtga tttaacacta ggcgtctgcg
     6301 gatggtttcc aatcggtccg ctaccggaag cctgagactt aatgaatgtg tgtatgggtc
     6361 gtgactgcta ttaaggtggg gacttagggt ctctccccta tagtgatagt ttagtccccc
     6421 cccttcccct atagtgtggg tttcattcgt tagcggcctg ctgctgctcc ctcgcctgtc
     6481 tgtcctgatt ctcaatacct tgacgtggac cttcaggcat actctggaac atagcctcaa
     6541 tttctttcgg tctcgtgatt cggtcatcga caataatgtt cagcagctta aagagaccgt
     6601 gtgccaactg cgggtcatca tcaagactaa tctctccggg atggaccgcc tgattgccga
     6661 caatacgaca gatatctgcc gcctgctgga tgcgtacagg tagtcctttc tggacgagtg
     6721 accggatgtc tttattaatg ttttctcccg gctcgcctaa gtggaccatt agcttctgaa
     6781 ggcaaagacg aaggagtgca gcggcccctt taggagacag attaatgatg cttcgggctt
     6841 ccatatagtc ggacttgcag ttatctggca tatctggatt tggtagttca acattgccag
     6901 ccgccggaat aatcatattg ccgtcatacc aataagcatc atcaccgcaa tgagagcatg
     6961 ttgacattcg gaactcggtt gtcctttgcg ccaactcacg cgcacttcca tacatcctac
     7021 gcc
//
LOCUS       DAPOAV010000151         6918 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.152, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000151 DAPOAV010000000
VERSION     DAPOAV010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6918
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.152"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            135..356
                     /gene="traR"
                     /locus_tag="RN951_004182"
     CDS             135..356
                     /gene="traR"
                     /locus_tag="RN951_004182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraR"
                     /protein_id="HDX2529085.1"
                     /translation="MSDEADEAYSVTEQLTMTGINRIRQEINVHGIPVYLCEACGNPI
                     PEARRKIFPGVTLCVECQAYQERQRKHYA"
     gene            349..825
                     /locus_tag="RN951_004183"
     CDS             349..825
                     /locus_tag="RN951_004183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000549587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529086.1"
                     /translation="MHKSENEKIDFILDEHERISRKQGSLCMALGKGFLVIAILCGVA
                     TFCVSGLYLKSLCLSVACCCGVFSRIFNYYSVPEESRMVLSRQELLRLMRLTEDVPDV
                     RQELLNRLLSGKKLTGRDEQDIRRLWQEKVDAMQESATRQREQDTIRKFTEGNKSE"
     gene            905..1123
                     /locus_tag="RN951_004184"
     CDS             905..1123
                     /locus_tag="RN951_004184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000556745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529087.1"
                     /translation="MHTFIFLVLIKNINGGGSWNITPMPNTDVCVQVLRTIEAHGGRG
                     FGNTGECIEVKTNEPLNSVMETLNGGGQ"
     gene            1151..1498
                     /locus_tag="RN951_004185"
     CDS             1151..1498
                     /locus_tag="RN951_004185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529088.1"
                     /translation="MKSIYLKSVLAFIFVGVMAMIVCIPFYIVYLAQQPATPEQLTEI
                     LQETPCAAEAFQETLNYQSEPLTLGKANKIASECRKRNEMAEVKRVRENERNKIREKQ
                     IQALNDAHSVKER"
     gene            1624..4254
                     /gene="traC"
                     /locus_tag="RN951_004186"
     CDS             1624..4254
                     /gene="traC"
                     /locus_tag="RN951_004186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein TraC"
                     /protein_id="HDX2529089.1"
                     /translation="MSNNPLEAVTQAVNSLVTALKLPDESAKANEVLGEMSFPQFSRL
                     LPYRDYNQESGLFMNDTTMGFMLEAIPINGANKSIVEALDHMLRTKLPRGIPLCIHLM
                     SSQLVGDRIEYGLREFSWSGEQAERFNAITRAYYMKAAATQFPLPEGMNLPLTLRHYR
                     VFISYCSPSKKKSRADILEMENLVKIIRASLQGASIATQTVDAQAFIDIVGEMINHNP
                     DSLYPKRRQLDPYSDLNYQCVEDSFDLNVRADYLTLGLRENGRNSTARILNFHLARNP
                     EIAFLWNMADNYSNLLNPELSISCPFILTLTLVVEDQVKTHSEANLKYMDLEKKSKTS
                     YAKWFPSVEKEAKEWGELRQRLGSGQSSVVSYFLNITAFCKDNNETALEVEQDILNSF
                     RKNGFELISPRFNHMRNFLTCLPFMAGKGLFKQLKEAGVVQRAESFNVANLMPLVADN
                     PLTPAGLLAPTYRNQLAFIDIFFRGMNNTNYNMAVCGTSGAGKTGLIQPLIRSVLDSG
                     GFAVVFDMGDGYKSLCENMGGVYLDGETLRFNPFANITDIDQSAERVRDQLSVMASPN
                     GNLDEVHEGLLLQAVRASWLAKENRARIDDVVDFLKNASDSEQYAGSPTIRSRLDEMI
                     VLLDQYTANGTYGQYFNSDEPSLRDDAKMVVLELGGLEDRPSLLVAVMFSLIIYIENR
                     MYRTPRNLKKLNVIDEGWRLLDFKNRKVGEFIEKGYRTARRHTGAYITITQNIVDFDS
                     DKASSAARAAWGNSSYKIILKQSAKEFAKYNQLYPDQFQPLQRDMIGKFGAAKDQWFS
                     SFLLQVENHSSWHRLFVDPLSRAMYSSDGPDFEFVQQKRKEGLSIHEAVWQLAWKKSG
                     PEMASLEAWLEEHEKYRSVA"
     gene            4251..4637
                     /gene="trbI"
                     /locus_tag="RN951_004187"
     CDS             4251..4637
                     /gene="trbI"
                     /locus_tag="RN951_004187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system protein TrbI"
                     /protein_id="HDX2529090.1"
                     /translation="MTTTQKTTDVTAPRRSHWWWTVPGCLAMVLLNAAVSYGIVRLNA
                     PVTAAFNMKQTVDAFFDSASQKQLSEAQSKALSARFNTALEASLQAWQQKHHAVILVS
                     PAVVQGAPDITREIQQDIARRMRAEP"
     gene            4634..5266
                     /gene="traW"
                     /locus_tag="RN951_004188"
     CDS             4634..5266
                     /gene="traW"
                     /locus_tag="RN951_004188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system protein TraW"
                     /protein_id="HDX2529091.1"
                     /translation="MRCRGLIALLIWGQSVAAADLGTWGDLWPVKEPDMLTVIMQRLT
                     ALEQSGEMGRKMDAFKERVIRNSLRPPAVPGIGRTEKYSSRLFDPSVRLAADIRDNEG
                     RVFARQGEVMNPLQYVPFNQTLYFINGDDPAQVAWMKRQTPPTLESKIILVQGSIPEM
                     QKSLDSRVYFDQNGVLCQRLGIDQVPARVSAVPGDRFLKVEFIPAEEGRK"
     gene            5263..6255
                     /locus_tag="RN951_004189"
     CDS             5263..6255
                     /locus_tag="RN951_004189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer pilus assembly protein TraU"
                     /protein_id="HDX2529092.1"
                     /translation="MKRSLWLLMLFLLAGHVPAASADSACEGRFVNPITDICWSCIFP
                     LSLGSIKVSQGKVPDTANPSMPIQICPAPPPLFRRIGLAIGYWEPMALTDVTRSPGCM
                     VNLGFSLPAFGKTAQGTAKKDEKQVNGAFYHVHWYKYPLTYWLNIITSLGCLEGGDLD
                     IAYLSEIDPTWTDSSLTTILNPEAVIFANPIAQGACAADAIASAFNMPLDVLFWCAGS
                     QGSMYPFNGWVSNESSPLQSSLLVSERMAFKLHRQGMIMETIGKNNAVCNEYPSPILP
                     KERWRYQMVNMYPDSGQCHPFGRSVMRWETGKNPPNTKKNFGYLMWRKRNCVFL"
     gene            6285..6590
                     /locus_tag="RN951_004190"
     CDS             6285..6590
                     /locus_tag="RN951_004190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001505125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529093.1"
                     /translation="MATMDSKYIQHLRKISAVLLRLISRTLKLFPFGLVIVPVILFYF
                     APDSFLAEIIHEWKNADISEQVTLVRLYLKVTFTCAFVAVFLNYLFSDEFMPVNSRK"
     gene            6599..>6918
                     /locus_tag="RN951_004191"
     CDS             6599..>6918
                     /locus_tag="RN951_004191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001733892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly protein TrbC"
                     /protein_id="HDX2529094.1"
                     /translation="MNRKIFALFALTAGMHLAVHASENVNTTENRQFLKQQENLSRQL
                     REKPDHQLKAWAEKQVLENPLQRSDNHFLDELVRKQQASQDGKPRQGALYFVSFSIPE
                     EGLKR"
BASE COUNT         1746 a         1643 c         1897 g         1632 t
ORIGIN      
        1 ctggccctga agttgtatat cagccggcaa tgccggcggg ctttctgtat tcaaaatccg
       61 cctgtaaaac gagtgccctg tgcgtgaaaa gggatgggcg gtagcgtgtc agaacatgtc
      121 gggaggaata ttccgtgagt gatgaagccg atgaagcata ttcagtgaca gaacaactga
      181 ccatgacagg aataaaccgg atacgccagg aaataaatgt tcatggtatt cctgtttatc
      241 tctgtgaagc atgcggaaat cctattccgg aagcccggcg gaaaatattt cccggtgtga
      301 cgttgtgcgt tgaatgtcag gcgtatcagg aaaggcagag gaaacactat gcataaatca
      361 gaaaatgaaa aaatagattt tattctggat gagcatgagc ggatatccag aaaacagggt
      421 tctttgtgta tggcactggg taagggattt ttagttatag ctattctttg tggtgttgcc
      481 acattctgtg tttctggcct gtatctgaaa tccctgtgcc tgtccgttgc ctgctgttgt
      541 ggggtattca gtcgtatttt taattattac agcgtaccgg aggaatcacg catggtactc
      601 agtcgtcagg aattactccg gcttatgcgt ctgactgaag acgtaccaga tgtgagacag
      661 gaactgctta accgtttgtt gtccggtaaa aaactgactg gtcgggatga acaggatatc
      721 cggcgtctct ggcaggagaa agtggatgca atgcaggagt ctgccacccg tcagcgtgaa
      781 caggatacta ttcggaagtt tactgaaggg aataaatccg aatgagaatc tgcagtgttt
      841 tatgacctca taagttaact gaagggatat tcagtgatta atatacaagc ggagataata
      901 aagaatgcat acctttattt ttcttgtgct gataaaaaat attaacggtg gcggaagctg
      961 gaatattaca cccatgccaa atacggacgt atgcgtgcag gttcttcgga caatcgaagc
     1021 acatggcggc aggggctttg gaaatacagg ggagtgtatt gaagttaaaa caaatgaacc
     1081 tttgaacagc gtgatggaaa cactaaatgg tggtgggcaa tgagtgctta ctgcttcgaa
     1141 ggaaaatgaa atgaagtcga tatatttaaa atctgttctg gcttttatat ttgttggcgt
     1201 tatggctatg attgtatgta ttccttttta catcgtttac cttgcgcaac aacctgcaac
     1261 accagaacaa ctgacagaga ttttacagga aactccctgt gcagcagaag catttcagga
     1321 gacacttaat tatcagtctg aacctttaac acttggtaag gcaaataaaa tcgcatcaga
     1381 atgcagaaaa agaaacgaaa tggcagaggt gaaacgtgta agagaaaatg agcgcaataa
     1441 gattcgcgaa aaacaaattc aggcattaaa tgatgctcat tcagtaaagg aacgttaatc
     1501 ctggtttcct gttaaaagcc tccatctctt atttgtgctg tggtttcagg aatggcactg
     1561 cgtgatatat ccacggccac agactgatat tttccttttt taaacgcact aaggaatact
     1621 catatgagta ataacccact tgaggccgtc actcaggcgg ttaactccct cgtcacagca
     1681 ctgaaactgc ctgacgaatc cgcaaaggcc aatgaagttc tgggcgaaat gagcttcccg
     1741 cagttcagcc gtctgctgcc gtaccgtgat tacaaccagg aatccggtct gttcatgaat
     1801 gacaccacga tgggctttat gctggaagcc attcccatca atggggcgaa taagtccatt
     1861 gtggaggcac tcgatcacat gctgcgcacc aaactgccgc gcggtattcc gttgtgtatc
     1921 catctgatgt ccagtcagct ggttggtgac aggattgagt acgggctgcg tgagttctcc
     1981 tggtcaggtg aacaggctga acggtttaac gccattaccc gggcctatta tatgaaagcg
     2041 gcagcgacac agtttccgct gccggagggg atgaatctgc ccctgaccct gcgccattac
     2101 cgggtattta tctcgtactg ttctccctcg aagaaaaaaa gccgggctga cattctggaa
     2161 atggaaaacc tggtgaaaat catccgggcg tcgttacagg gggccagtat cgccacacag
     2221 acggtggatg cacaggcctt tatcgatatt gtcggggaga tgattaacca taacccggac
     2281 tccctgtacc cgaaaagacg tcagctggac ccgtattctg atctgaatta tcagtgtgtg
     2341 gaggacagtt ttgacctgaa tgtccgggct gattacctga cgctgggcct gcgtgagaac
     2401 ggcaggaaca gcacggcccg tatcctgaat ttccatctgg cccgtaaccc ggaaatcgcc
     2461 ttcctgtgga atatggccga caactacagc aacctgctga acccggaact gtccatctcc
     2521 tgtccgttca tcctgacgct gactctggtg gtggaagacc aggtgaaaac ccacagcgaa
     2581 gccaacctga agtacatgga cctggagaaa aagtcgaaga cctcctatgc caaatggttt
     2641 ccgtccgtgg agaaagaggc gaaggagtgg ggggaactgc gtcagcgtct gggctccggt
     2701 cagtcttctg tcgtgtccta cttcctcaac atcacagcat tctgcaagga caacaatgaa
     2761 acggcgctgg aagtggagca ggacatcctg aacagcttcc gtaaaaacgg ttttgagctg
     2821 atttcaccgc gctttaacca catgcgcaat ttcctgacct gtctgccctt tatggccggg
     2881 aaagggttgt ttaaacagct gaaagaggcc ggagtggttc agcgcgcaga gagctttaat
     2941 gttgccaacc tgatgccgtt agtggcggat aaccccctga caccggcagg tctgctggca
     3001 cccacctacc gtaaccagct ggcgtttatc gatattttct tccgggggat gaataacacc
     3061 aactacaaca tggcggtctg tggcacctcc ggggccggta aaaccgggct gatacagcca
     3121 cttatccgca gcgtgctgga ctccgggggc tttgccgtgg tgttcgacat gggggatggc
     3181 tacaagtccc tgtgtgagaa catgggtggc gtatatctgg acggtgaaac cctgcgtttt
     3241 aacccgtttg cgaacatcac cgatattgac cagtcagcgg agcgtgtccg tgaccagttg
     3301 tcagtgatgg ccagccccaa cggtaacctg gatgaagtgc atgaaggtct gctgctgcag
     3361 gcggtcaggg cctcctggct ggccaaagag aacagggcac gtattgatga cgtggtggat
     3421 ttcctgaaaa acgccagtga cagcgagcag tatgccgggt caccgaccat ccgcagccgt
     3481 ctggacgaaa tgattgtgct gcttgaccag tacactgcca acggcactta cggccagtat
     3541 tttaactccg atgagccgtc cctgcgggat gatgcgaaaa tggtggtgct ggagctgggc
     3601 ggactggaag accgtccgtc actgctggtt gcggtgatgt tctccctgat tatctacatc
     3661 gagaacagga tgtaccgcac gccgcgtaac ctcaagaaac tgaacgttat tgatgaaggc
     3721 tggcgtctgc tggacttcaa aaatcgcaag gtcggtgagt ttattgagaa aggttaccgt
     3781 accgcccgcc gtcataccgg tgcctatatc accatcacac agaacatcgt cgactttgac
     3841 tctgacaagg cctccagtgc ggcccgtgcg gcatggggta actcctccta caaaattatc
     3901 ctcaaacaga gtgcgaagga gttcgcaaaa tacaaccagc tgtatccgga ccagttccag
     3961 ccactgcagc gcgacatgat tggtaagttt ggtgcggcca aagaccagtg gttcagttcc
     4021 ttcctgctgc aggtggaaaa ccattcctcc tggcaccgcc tgtttgtgga cccgttaagc
     4081 cgcgccatgt acagctctga cggcccggat tttgagtttg tgcagcagaa acgtaaagag
     4141 gggctgagta ttcatgaggc ggtgtggcag ctggcgtgga agaagtcagg gccggagatg
     4201 gcttcgctgg aagcctggct ggaagaacat gagaaataca ggagtgttgc atgaccacaa
     4261 cgcaaaaaac gacggatgtt acagcccccc gacgcagcca ctggtggtgg acggtgccgg
     4321 gatgcctggc aatggtgtta ctgaacgcag ccgtcagtta cggcattgtc agactgaacg
     4381 caccggtgac tgccgccttc aacatgaaac agaccgtgga tgcgtttttt gacagcgcca
     4441 gtcagaaaca actgtcagaa gcacagtcaa aagccctttc agcgcgtttt aacacggcac
     4501 tggaagccag cctgcaggcg tggcagcaga aacaccacgc ggtcatcctg gtgtcgcctg
     4561 ccgtggtaca gggggctccg gatatcaccc gggaaatcca gcaggatatt gcccggcgaa
     4621 tgagagcgga accatgagat gccgggggct gattgccctg ctgatatggg ggcagagtgt
     4681 ggccgccgcc gatcttggca cctggggcga tctgtggccg gtaaaggagc cggacatgct
     4741 gacggtgatc atgcagcgcc tgacggcact ggagcagtcc ggtgagatgg gccggaaaat
     4801 ggatgccttt aaggagcggg tgatccgcaa cagtctgcgg ccccctgccg tgcccggtat
     4861 cggacgcacg gagaaataca gcagccggtt gtttgacccg tccgtcagac tggctgcgga
     4921 tatccgggat aacgaagggc gggtgtttgc ccgtcagggt gaagtgatga atccgctgca
     4981 gtatgtgcct tttaaccaga cgctgtattt catcaatggc gatgatccgg cgcaggtggc
     5041 ctggatgaaa cgccagacgc cgcccacact ggagagcaaa attatcctcg tgcagggcag
     5101 tatcccggag atgcagaagt ctctggacag ccgtgtttac tttgaccaga acggtgtgct
     5161 ctgccagcgc ctcggcattg atcaggtccc ggcacgggtg agcgccgttc ccggcgatcg
     5221 cttcctgaag gtggaattta ttccggcaga ggagggcaga aaatgaagcg aagcctgtgg
     5281 ctgctgatgt tattccttct cgccggtcat gtccctgcgg catctgcgga ttctgcctgt
     5341 gaggggcgtt ttgtaaaccc gatcacggat atctgctgga gctgtatttt cccgctctcg
     5401 ctgggcagta tcaaagtcag tcagggtaag gtccccgaca cggcgaaccc gtcgatgccc
     5461 attcagattt gtccggcacc gccgccgctg ttcaggcgta tcgggctggc cattggttac
     5521 tgggagccga tggcgctgac ggacgtcacc cggtcaccgg gatgcatggt gaacctgggc
     5581 ttcagcctgc cggcttttgg taaaacggca cagggaacgg cgaaaaagga tgagaagcag
     5641 gtgaacgggg cgttctatca cgttcactgg tacaaatacc cgctgacgta ctggcttaac
     5701 atcatcacat cgctgggctg tctggaaggt ggtgacctgg atatcgctta tctttctgaa
     5761 attgacccca cctggacgga cagcagcctg accaccattc tcaatccgga agctgtcatc
     5821 tttgccaatc cgatagcaca gggggcctgt gcagcagatg ccattgccag cgcctttaat
     5881 atgcctctcg atgttctgtt ctggtgtgcc ggttcgcagg gcagtatgta cccgttcaat
     5941 ggctgggtga gtaatgagtc cagtccgttg cagtcctccc tgctggtcag tgaacgcatg
     6001 gcgttcaaac tacaccgtca gggcatgatt atggaaacca tcgggaaaaa taacgccgtc
     6061 tgtaatgaat atccgtcccc aatcctgcct aaagaacgct ggcgttatca gatggtgaat
     6121 atgtatccgg acagcggaca gtgccatccg ttcgggcgca gtgtgatgcg ctgggagacg
     6181 ggaaaaaatc cgcccaacac aaagaaaaac ttcggctacc tgatgtggcg taaacgtaac
     6241 tgtgtattcc tgtaaatcat tttaatgaat aagaggaaat gaaaatggca acaatggaca
     6301 gtaaatatat tcagcacctc aggaaaataa gtgctgtact gctcaggctg ataagcagaa
     6361 cattaaaatt atttcctttt ggtcttgtaa tagtgcccgt tatattattt tattttgcac
     6421 ctgacagttt tctcgctgaa attattcatg aatggaagaa cgcagatata tcagaacaag
     6481 tgacacttgt cagattatat ctgaaggtga catttacatg tgcgtttgtg gctgtttttc
     6541 tcaattatct tttttctgat gagttcatgc ctgtaaatag cagaaagtga gaaatatcat
     6601 gaaccggaaa atatttgcac tttttgctct gacagcaggg atgcatcttg ctgttcatgc
     6661 ttcagaaaat gtgaacacaa ctgaaaaccg ccagttcctg aagcagcagg aaaatttaag
     6721 cagacaactg cgagagaaac ctgaccatca gctgaaagcc tgggcggaga aacaggtgct
     6781 ggaaaacccc cttcagcgtt cagataacca ttttctggat gagctggttc gtaaacagca
     6841 ggcttcgcag gacgggaaac cccggcaggg tgccctgtat tttgtgtcgt tttccattcc
     6901 cgaagagggg ctgaaacg
//
LOCUS       DAPOAV010000152         6859 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.153, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000152 DAPOAV010000000
VERSION     DAPOAV010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6859
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.153"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            125..1345
                     /gene="arcA"
                     /locus_tag="RN951_004192"
     CDS             125..1345
                     /gene="arcA"
                     /locus_tag="RN951_004192"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HDX2529095.1"
                     /translation="MEKHYVGSEIGQLRSVMLHRPNLSLKRLTPSNCQELLFDDVLSV
                     ERAGEEHDIFANTLRDQGVEVLLLTDLLTQTLDIKEAKTWLLETQISDYRLGPTFAGD
                     VRSWLADMPHRELARRLSGGLTYGEIPAAINNMVVDTHTSNDFIMKPLPNHLFTRDTS
                     CWIYNGVSINPMAKPARQRETNNLRAIYRWHPAFADGDFIKYFGDENIYYDHATLEGG
                     DVLVIGRGAVLIGMSERTTPQGVEFLANSLFKHRQAERVIAVELPKHRSCMHLDTVMT
                     HIDVDTFSVYPEVVRKDAQCWTLTSNGRDGLQRTQETDLLHAIEKALGIDQVRLITTG
                     GDAFEAEREQWNDANNVLTIRPGVVIGYERNVWTNEKYDKAGITVLPIPGDELGRGRG
                     GARCMSCPLERDGI"
     gene            1356..2267
                     /gene="arcC"
                     /locus_tag="RN951_004193"
     CDS             1356..2267
                     /gene="arcC"
                     /locus_tag="RN951_004193"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006810310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HDX2529096.1"
                     /translation="MERKPTLVVALGGNALLKRGEPLEAEIQRQNIELAARTIAGLTV
                     NWRVVLVHGNGPQIGLLALQNSAYDKVTPYPLDVLGAESQGMIGYMLQQALKNSLPQR
                     EVSVLLTQVEVDATDPAFSNPTKYIGPVYNEDQAKTLAAEKGWGFKADGSYFRRVVPS
                     PQPKRIVESDAITALIQRDHLVICNGGGGVPVVEKANGYRGIEAVIDKDLSAALLAYQ
                     IGADALLILTDADAVYLYWGKPTQRPLAQVTPELLRGMQFDTGSMGPKVAACCKFVEA
                     CNGIAGIGALVDGAEILAGNKGTLIRN"
     gene            2352..3356
                     /gene="argF"
                     /locus_tag="RN951_004194"
     CDS             2352..3356
                     /gene="argF"
                     /locus_tag="RN951_004194"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDX2529097.1"
                     /translation="MTINLKKRNFLKLLDYTPAEIQYLIDLAIKLKAAKKAGREKQTL
                     VGKNIALIFEKTSTRTRCAFEVAAFDQGAQVTYLGPGGSQIGHKESMKDTARVLGRMY
                     DGIEYRGYGQAIVEELGKYAGVPVWNGLTDEFHPTQILADLMTMLEHSPGKKLSELSF
                     AYLGDARNNMGNSLMVGAAKMGMDIRLVAPKSFWPDVVLVEQCRSIAEETGARITLTD
                     DVEEGVWGTDFLYTDVWVSMGEPKEAWTERVSLMKPYQINADVMNATGNPNVKFMHCL
                     PAFHNEHTKVGREIEMAYGLKGLEVTEEVFESPNSIVFDEAENRMHTIKAVMVATLGD
                     "
     gene            3404..4807
                     /locus_tag="RN951_004195"
     CDS             3404..4807
                     /locus_tag="RN951_004195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HDX2529098.1"
                     /translation="MGKFKFPSAYTILFFLIAIVAVLTWIIPAGQYHMAMNEALGKEV
                     PVAGTYAHVEANPQGLISVLMAPIAGLYDPDSGQARAIDVALFILIIGGFLGIVTKTG
                     AIDAGIERVTTRLRGREEWMIPILMALFAAGGTIYGMAEESLPFYTLLVPVMLAARFD
                     PVVAASTVLLGAGIGTLGSTINPFATVIAANAAGIPFTNGITLRVVVLVIGWIICVTW
                     VMRYARKVRKEPSLSIIADKQEENLAHFLGNKSEQALEFTPVRKIILVIFALTFAVMI
                     YGVAVLGWWMAEISTVFLASAIIIGLIARMSEEELTSTFINGARDLLGVALIIGIARG
                     IVVIMDKGMITHTILHYAEGMVTGLSTVAFINVMYWLEVVLSFLVPSSSGLAVLTMPI
                     MAPLADFANVNRDLVVTAYQSASGIVNLITPTSAVVMGGLAIAHVPYVRYLKWVAPLL
                     GILTVVIMVALSLGALL"
     gene            4888..5367
                     /locus_tag="RN951_004196"
     CDS             4888..5367
                     /locus_tag="RN951_004196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003863366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HDX2529099.1"
                     /translation="MMDYEDFSPKEQLQLTVCQRLIAEKSYFSQEELRRDLQERGFET
                     ISQSTVSRLLNLLGVIKIRNAKGLKVYSLNPQLRPAPDAARTVSEMVVSVEHNREFIL
                     IHTVAGYGRAVARVLDYHQLPEILGVVAGSSIVWVAPRMVKRVALVHKQINYLLRTY"
     gene            complement(5431..5772)
                     /locus_tag="RN951_004197"
                     /pseudo
     CDS             complement(5431..5772)
                     /locus_tag="RN951_004197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014839879.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5724..5945)
                     /locus_tag="RN951_004198"
     CDS             complement(5724..5945)
                     /locus_tag="RN951_004198"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529100.1"
                     /translation="MSQKYLIRIAELESQLRQKDQQLSLVEETEAFLRSALARAEEKI
                     EEDEREIEYLRAQARCRKNPGWAKRSAMY"
     gene            complement(5976..6326)
                     /gene="tnpB"
                     /locus_tag="RN951_004199"
     CDS             complement(5976..6326)
                     /gene="tnpB"
                     /locus_tag="RN951_004199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017901265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDX2529101.1"
                     /translation="MISLPSGTRIWLVAGVTDMRKSFNGLGEQVQHVLNDNPFSGHLF
                     IFRGRRGDTVKILWADADGLCLFTKRLEEGQFIWPVVRDGKVSITRSQLAMLLDKLDW
                     RQPKTSRLNALTML"
     gene            complement(6323..6685)
                     /locus_tag="RN951_004200"
     CDS             complement(6323..6685)
                     /locus_tag="RN951_004200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001362728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDX2529102.1"
                     /translation="MRMVELASQPGACVAQIARENGVNDNVIFKWLRLWQNEVRISRR
                     IPVTTTSDAGVELLPVEITPDEPKEPMAALTPSLSTQTTVSASSCKVEFRHGNMTLEN
                     PSPELLTVLIRELTGRGR"
     gene            complement(6794..>6859)
                     /locus_tag="RN951_004201"
     CDS             complement(6794..>6859)
                     /locus_tag="RN951_004201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="HDX2529103.1"
                     /translation="SKSVELHDKVIGHYLNIKHYQ"
BASE COUNT         1625 a         1781 c         1829 g         1624 t
ORIGIN      
        1 atcacaataa tgtttatttt accgcctagt atgaaccacg aaatcaattg aagttagccg
       61 ccatgaaatt aaatacacaa catggcgcat acctttttat tctaaaaaaa ttaaaggaat
      121 aattatggaa aaacattacg tcggttctga aattggtcaa ttgcgtagtg ttatgctgca
      181 ccgcccaaat ttaagtctga aacgtttgac accatcgaat tgtcaggaac tgcttttcga
      241 tgatgtactc tcggttgaac gggcaggtga agagcatgac atcttcgcaa atacgctgcg
      301 cgatcagggg gtggaagtcc tgctgttaac agacctcctg acacaaaccc ttgatattaa
      361 agaagcgaaa acttggttac tggagacgca aatttctgac taccgcctcg gacctacctt
      421 tgcgggcgat gtgcgcagct ggctggcgga catgccgcac cgtgaactgg cgcgaagatt
      481 aagcggcgga ttaacttacg gtgaaattcc ggctgccatt aacaatatgg tggtggatac
      541 ccacacgtct aatgacttta ttatgaagcc gctaccgaat catttattta cccgcgatac
      601 ctcctgctgg atttataacg gtgtttctat taacccgatg gccaaaccag cccgtcaacg
      661 tgaaaccaat aacctccggg caatatatcg ctggcacccg gcatttgccg acggcgattt
      721 tattaagtat ttcggcgacg aaaatattta ttacgaccac gccactttgg aaggtggcga
      781 cgtattagtg attggtcgtg gggcggtatt gatcggcatg tctgaacgca caacaccgca
      841 gggcgtggag ttcctcgcca acagcctgtt caaacatcgt caggccgagc gagtgatcgc
      901 cgttgagctg ccaaaacacc gctcctgtat gcaccttgac accgtcatga cccacatcga
      961 cgttgacact ttctccgttt acccggaagt ggtgcgcaaa gacgcccagt gctggacgct
     1021 cacttcgaac ggacgcgatg gcctacaacg gacccaggaa accgacctgt tgcacgccat
     1081 cgagaaagca ctcggtattg accaggtacg cttgatcacc accggcggcg acgcctttga
     1141 agccgaacgt gagcagtgga acgacgccaa taacgttctg accatccgcc ccggtgtggt
     1201 gattggttac gagcgcaacg tctggactaa cgagaaatac gacaaagccg gcatcaccgt
     1261 gctgcccatc ccgggggacg aattgggacg aggccgcggc ggcgcacgct gcatgagctg
     1321 tccgcttgaa cgcgacggaa tttaaaggag ccatcatgga acgaaaaccc actttggttg
     1381 tggcgttggg cggcaacgca ttattgaagc gcggcgaacc actggaagca gaaatccagc
     1441 gccagaacat tgagttggcc gcccgtacca tcgccgggct cacggtgaat tggcgcgtgg
     1501 tgttggttca cggcaacggt ccacagatcg ggctgctggc gctgcagaac agcgcctacg
     1561 acaaagtgac cccttatcca ctggacgttc ttggcgccga aagccagggg atgatcggct
     1621 acatgctcca gcaggcgctg aaaaacagcc tgccacagcg tgaggtgagc gtcctgctta
     1681 ctcaggtgga agtggacgct actgacccgg cgttcagcaa cccgaccaaa tatatcggac
     1741 cggtgtacaa cgaagaccag gcaaaaacac tggcagcaga aaaaggttgg gggtttaagg
     1801 ccgacggcag ctacttccgt cgcgtggtgc catctccaca gccgaaacgc attgtcgaga
     1861 gcgatgctat tacggcactg atccagcgcg accatcttgt tatctgcaac ggcggcggtg
     1921 gtgtaccagt tgtggaaaag gctaacggct atcgcggaat tgaggcggtg atcgacaaag
     1981 acctctctgc tgccctgctg gcataccaga taggggccga cgcactactg attctcactg
     2041 atgccgacgc ggtttacctc tattggggca aaccgaccca gcgtccgcta gcgcaggtga
     2101 cgccagaact gctcagaggc atgcagtttg acaccggatc gatggggccg aaagtggccg
     2161 cctgctgcaa gtttgttgaa gcttgcaacg gtattgccgg gatcggcgct ctggtcgacg
     2221 gggctgagat tttggcgggc aataaaggca cattgattcg taactgaatc ccccttcacc
     2281 taaccctctc ctcaaagggg agatggcaga gtgagggcat cagacagtta aaatttaaaa
     2341 aggatttcct aatgaccatc aatttgaaaa aacgcaactt ccttaaactg ctggactaca
     2401 ccccggcaga gatccagtac ctgatcgatc tcgcgatcaa actgaaagcg gccaaaaaag
     2461 ccggacgaga aaaacagacc ttggttggca aaaacattgc cctgattttt gaaaaaacct
     2521 ccacccgtac ccgctgtgct ttcgaagtgg ctgcgttcga ccaaggggcg caggtgacct
     2581 acctcggccc aggcggatcg caaatcggcc ataaagagtc aatgaaagac accgcccgtg
     2641 tgctgggccg tatgtatgac ggcatcgaat accgtggtta cggtcaggcc atcgttgagg
     2701 agttgggcaa atacgcgggc gtaccggtgt ggaacggtct gaccgacgaa tttcacccaa
     2761 cccaaatcct cgcagatttg atgaccatgc tggaacattc cccgggcaaa aaactgtcgg
     2821 aactgagctt tgcctacctt ggcgacgcac gcaacaacat gggtaactcc ctgatggtgg
     2881 gggctgccaa aatggggatg gatatccgtc ttgtagcccc aaaatccttc tggccggatg
     2941 tggtgcttgt tgaacagtgc cgttccatcg cggaagagac gggcgcacgt atcaccctga
     3001 ccgatgacgt ggaagaaggc gtgtggggaa cggatttcct ctacaccgat gtttgggtct
     3061 caatgggtga accgaaagag gcgtggaccg aacgcgtcag cctgatgaag ccttatcaaa
     3121 tcaacgctga cgtgatgaac gccaccggca acccgaacgt caagttcatg cactgcctgc
     3181 cagccttcca caatgagcac accaaagtgg gccgagaaat tgagatggca tacggcctga
     3241 agggactgga ggtgacggaa gaggtcttcg aatcccctaa ctctatcgtc tttgatgaag
     3301 cagaaaaccg catgcatacc attaaagcgg tcatggtggc gacactcggc gactaatcac
     3361 cacccggtgc gtcgtagggg gcaccgggtc tcaggagaac atcatgggta agttcaaatt
     3421 tccctccgca tataccattc tcttttttct gattgccatc gttgccgtcc tgacgtggat
     3481 cattccagcc gggcagtatc acatggcaat gaacgaagct ctcggcaagg aggttcctgt
     3541 tgccggcacc tatgcacacg tagaggccaa tccgcaggga ctgatttcag tgctgatggc
     3601 cccaattgcc gggttgtatg atccagactc cggtcaggct agggcgatag acgttgcgct
     3661 gtttattctg atcatcggag gattcctcgg gatcgtcacc aaaaccgggg ccattgacgc
     3721 cggaatcgag cgcgtcacca cccgactacg tggtcgcgaa gagtggatga tcccgatcct
     3781 tatggcgctg tttgctgctg gcggtacaat ttacggcatg gccgaagaat ccctgccgtt
     3841 ttataccctg ctggtgccgg tgatgttggc agcacgcttc gaccctgtgg tagccgcctc
     3901 caccgtgctg ctcggcgccg ggatcggcac gctcggctcc accattaacc ctttcgcgac
     3961 ggtgatcgcc gccaatgcag ccgggatccc cttcaccaac ggtatcacct tgcgtgtggt
     4021 ggtgcttgtc atcggctgga taatctgcgt gacatgggtg atgcgctatg cccggaaagt
     4081 tcgcaaggag ccgtctctct ccattattgc ggataaacaa gaggagaacc tcgcccactt
     4141 cctcggcaat aaaagcgaac aggctctgga gttcaccccg gtacgcaaaa ttattctggt
     4201 gattttcgcc cttaccttcg cggtcatgat ctacggcgtg gcggtgctgg gttggtggat
     4261 ggcggagatc tcaacggtat ttctggccag cgcaattatc atcggtctga tcgcccgcat
     4321 gagcgaagag gaactgacct ctacctttat caacggcgcg cgagatttgc tgggcgttgc
     4381 actgattatc ggtatcgcgc gcggtatcgt agtgatcatg gataaaggta tgattaccca
     4441 tactattttg cactacgccg agggaatggt tactggatta tcgacagtag cattcatcaa
     4501 cgtgatgtat tggctggaag tggtgctgtc gtttcttgtg ccttcttcgt ccggtctggc
     4561 cgttctgacg atgccgatca tggcacctct tgccgacttc gctaacgtca accgcgacct
     4621 ggtagttacg gcttaccagt ctgcgtccgg tatcgttaac ctgatcactc ccacctctgc
     4681 cgttgtgatg ggcggactgg ctatcgccca cgtgccttac gtgcgatatc tgaaatgggt
     4741 tgcgccgctg cttgggatat taacagtggt aattatggtg gcattaagtc tgggggcatt
     4801 gttgtaattt gccggatggc gctgccccta tccggtctac ggaatggtgt ggtgtcaccg
     4861 gttatttcga gaactgaata taggattatg atggattacg aagatttctc tcccaaagag
     4921 caactacagc taacggtctg ccaacgtctg attgcagaaa agagctattt ttcccaagag
     4981 gagcttcgcc gcgacttaca ggagcgtggt tttgagacaa tcagccagtc caccgtttct
     5041 cgtctgctca atttgttagg tgtcataaaa attcgaaatg ccaaagggct aaaagtctat
     5101 tcgctgaatc cacagttgcg tccggctcct gatgccgcgc gcactgtgtc cgaaatggtg
     5161 gtgagcgttg agcacaatag agaatttatc cttatccata ccgttgctgg atatggccgc
     5221 gcagtggcac gtgtccttga ttatcaccag ttaccagaaa ttttaggcgt ggtggccgga
     5281 agcagtatcg tctgggtcgc tcctcggatg gtgaagcgtg tcgctctggt gcataagcaa
     5341 attaattatt tactaagaac gtattaatat tcacaaatgc ccgcttgtat tgactaatac
     5401 gtaagcgtca acggagcacc gtattgacgc ttatttattg gtgagaacta cgttccatgg
     5461 caggagttcg tcaacacggt tggagggcca ttccggcagt acgctcagaa tatggcgcag
     5521 atacgcttcc ggatcgatac cgttcagacg gcaggtgccg atcagcccgt acagcagtgc
     5581 accacactcg ccgccgtgat cgctaccgaa gaacacgtaa tttttctttc cgagacagaa
     5641 tgcacgaagc gctctttccg ctgtgttatt gtccgcctcc gccagaccgt catcactgta
     5701 ataacagagg gcgtcccact gattcagtac atagctgaac gcttcgccca gcctggattt
     5761 tttcgacagc gtgcctgagc ccgcagatat tctatttccc gttcatcttc ttcgatcttt
     5821 tcttcggcac gtgccagtgc agagcgcagg aaggcctccg tctcttcaac cagactcagt
     5881 tgctggtctt tctgacggag ctggctttcc agttctgcaa tgcgaatgag gtatttctga
     5941 ctcatggccg tttttataat gcggccaggc gttttttaca acattgtcag ggcgttaagg
     6001 cgggatgttt ttggctgacg ccagtccagc ttatcgagga gcattgccag ttgcgagcgg
     6061 gtaatggata ccttgccgtc acgtaccaca ggccagataa actggccttc ctccaggcgt
     6121 ttggtgaaca ggcacagacc atcagcatca gcccaaagaa ttttaacggt gtcaccccgt
     6181 cggccacgga agataaacag gtgaccggag aagggattat cattcagcac atgttgtacc
     6241 tgttctccca gtccgttgaa ggatttacgc atatcggtaa cgccggcaac gagccagata
     6301 cgggtacctg atgggagtga gatcatcttc ccctcccggt cagttcacga atcaatacag
     6361 tgagcagctc tggtgaagga ttttccagcg tcatgttacc gtgacggaac tccaccttgc
     6421 aggagctggc actgacagta gtctgagtgg ataaggacgg agtaagagca gccatcggtt
     6481 ctttcggctc atcaggcgtt atctctacag gtaataattc aacgcctgcg tcagaagtgg
     6541 ttgtcaccgg aatacgccgt gatatacgca cttcgttttg ccagagtctg agccatttga
     6601 aaataacatt atcattgacg ccattttctc gtgcaatctg ggccacacaa gcaccgggtt
     6661 gtgatgccag ttcaaccata cgaattttga attcattcga atacttttta cgaggttctt
     6721 ttcgtcagtc ctgtaattcc atacttagat gtccgtctgt gtcagatggg cgtctaaggg
     6781 taatgactcc aacttattga tagtgtttta tgttcagata atgcccgatg actttgtcat
     6841 gcagctccac cgattttga
//
LOCUS       DAPOAV010000153         6845 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.154, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000153 DAPOAV010000000
VERSION     DAPOAV010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6845
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.154"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(242..727)
                     /gene="sixA"
                     /locus_tag="RN951_004202"
     CDS             complement(242..727)
                     /gene="sixA"
                     /locus_tag="RN951_004202"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohistidine phosphatase SixA"
                     /protein_id="HDX2529104.1"
                     /translation="MQVFIMRHGDAALDAASDSVRPLTTNGCDESRLMANWLKGQKVE
                     IERVLVSPFLRAEQTLEEVGDCLNLPSSAEVLPELTPCGDVGLVSAYLQALTNEGVAS
                     VLVISHLPLVGYLVAELCPGETPPMFTTSAIASVTLDESGNGTFNWQMSPCNLKMAKA
                     I"
     gene            complement(930..3074)
                     /gene="fadJ"
                     /locus_tag="RN951_004203"
     CDS             complement(930..3074)
                     /gene="fadJ"
                     /locus_tag="RN951_004203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadJ"
                     /protein_id="HDX2529105.1"
                     /translation="MEMTSAFTLNVRLDNIAVITIDVPGEKMNTLKAEFASQVRAIIK
                     QLRENKELRGVVFVSAKPDNFIAGADINMIGNCKTAQEAEALARQGQQLMAEIHALPI
                     PVIAAIHGACLGGGLELALACHGRVCTDDPKTVLGLPEVQLGLLPGSGGTQRLPRLIG
                     VSTALEMILTGKQLRAKQALKLGLVDDVVPHSILLEVAVELAKKDRPSSRPLPVRERI
                     LAGPLGRALLFKMVGKKTEHKTQGNYPATERILEVVETGLAQGTSSGYDAEARAFGEL
                     AMTPQSQALRSIFFASTEVKKDPGSDAPPAPLNSVGILGGGLMGGGIAYVTACKAGLP
                     VRIKDINPQGINHALKYSWDQLEGKVRRRHLKASERDKQLALISGTTDYRGFAHRDLI
                     IEAVFENLELKQQMVAEVEQNCAAHTIFASNTSSLPIGDIAAHATRPEQVIGLHFFSP
                     VEKMPLVEIIPHAGTSAQTIATTVKLAKKQGKTPIVVRDKAGFYVNRILAPYINEAIR
                     MLTEGERVEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIIPVLEAAYGERFSAPANVV
                     SSILNDDRKGRKNGRGFYLYGQKGRKSKKQVDPAIYPLIGAQGQGRLSAPQVAERCVM
                     LMLNEAVRCVDEQVIRSVRDGDIGAVFGIGFPPFLGGPFRYIDSLGAGEVVAIMQRLA
                     TQYGSRFTPCERLVEMGARGESFWKTTATDLQ"
     gene            complement(3074..4384)
                     /gene="fadI"
                     /locus_tag="RN951_004204"
     CDS             complement(3074..4384)
                     /gene="fadI"
                     /locus_tag="RN951_004204"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadI"
                     /protein_id="HDX2529106.1"
                     /translation="MGQVLPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMV
                     VGELLARSEIPAEVIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATS
                     FQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKKLARVLVDVNKARTMSQRLKLF
                     SRLRLRDLMPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWS
                     DGKLKEEVMTAFIPPYKQPLVEDNNIRGNSSLADYAKLRPAFDRKHGTVTAANSTPLT
                     DGAAAVILMTESRAKELGLVPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTM
                     SDLTLIDMHEAFAAQTLANIQLLGSERFAREVLGRAHATGEVDDSKFNVLGGSIAYGH
                     PFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE"
     gene            complement(4564..4848)
                     /locus_tag="RN951_004205"
     CDS             complement(4564..4848)
                     /locus_tag="RN951_004205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcZ/YiiS family protein"
                     /protein_id="HDX2529107.1"
                     /translation="MSKCSADETPVCCCMDVGTIMDNSDCTASYSRVFASRAEAEQTL
                     AALTEKARSVESEPCKITPTFTEESDGVRLDIDFTFACEAEMLIFQLGLR"
     gene            5220..6560
                     /gene="fadL"
                     /locus_tag="RN951_004206"
     CDS             5220..6560
                     /gene="fadL"
                     /locus_tag="RN951_004206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708225.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain fatty acid transporter FadL"
                     /protein_id="HDX2529108.1"
                     /translation="MSQKTLFTKSALAVAVALISTQAWSAGFQLNEFSSSGLGRAYSG
                     EGAIADDAGNVSRNPALITMFDRPTFSAGAVYIDPDVNISGTSPSGRSLKADNIAPTA
                     WVPNMHFVAPINDQFGWGASITSNYGLATEFNDTYAGGSVGGTTDLETMNLNLSGAYR
                     LNNAWSFGLGFNAVYARAKIERFAGDLGQLVAGQIMQSPAGQTPQGQALAATANGIDS
                     NTKIAHLNGNQWGFGWNAGILYELDKNNRYALTYRSEVKIDFKGNYSSDLNRAFNNYG
                     LPIPTATGGATQSGYLTLNLPEMWEVSGYNRVDPQWAIHYSLAYTSWSQFQQLKATST
                     SGDTLFQKHEGFKDAYRIALGTTYYYDDNWTFRTGIAFDDSPVPAQNRSISIPDQDRF
                     WLSAGTTYAFNKDASVDIGVSYMHGQSVKINEGPYQFESEGKAWLFGTNFNYAF"
BASE COUNT         1705 a         1841 c         1623 g         1676 t
ORIGIN      
        1 ttcaactcta ttatctgtat taataaatga caatgagtgt caaacagaca ttattcattt
       61 caacatgtaa ctttgggcaa aatcaagata cgcgcagaag aataatttcc gaatgaatgt
      121 agaaagtgtt ttatttatag ataaggagag tcttcgatag tagtgaggtt gacagatatc
      181 cgctgcctga tgagcaatta tgcccaatga atctacctca ttgggcataa tttggaacac
      241 atcagatagc ttttgccatc ttcagattac acgggctcat ctgccagttg aatgtaccgt
      301 ttccgctttc atcaagcgtt acgctggcaa tggccgaggt ggtaaacata ggcggcgttt
      361 cgcccggaca taactcggca accagatacc cgactaacgg taagtgagag atcaccagta
      421 ccgaagcaac accttcattg gtcaacgcct gcaaataggc actgaccaga ccaacatcgc
      481 cgcagggcgt taactccggc agaacttctg cactggaagg caggttcaga caatccccta
      541 cttcttccag tgtttgctcg gctcgcagga acgggctcac cagaacgcgt tcgatttcca
      601 ctttttgacc tttcagccag ttcgccatca ggcgagattc gtcacaacca ttagtggtca
      661 gaggacgaac ggaatcactg gcggcatcga gggctgcgtc gccgtgacgc atgataaaaa
      721 cttgcatatt gcaccgcttt tgttaaccag attcgcccgt tttctttcat ctgaaaccag
      781 agaaagaaaa cggtggccgg cattgtgcct tatccattca ccgaatgaaa cgctgttttt
      841 tacctcaatg gcgtaagtat agtcaatatg cgtttacatt ttgaccaaca ctccgccatt
      901 cagcgcggat tcatatagct ttgaccttct tattgcaggt cagttgcagt tgttttccaa
      961 aaactttccc cacgcgcgcc catctcgacc aaacgctcgc aaggggtaaa acgggaacca
     1021 tactgcgtgg caagtcgttg cattattgca accacttcgc ccgcgccgag agaatcgata
     1081 tagcggaacg gtccaccgag aaatggcgga aaaccaatgc caaataccgc accaatatcc
     1141 ccgtcacgca cgctacggat aacctgctca tcaacacaac gtactgcttc attcagcatc
     1201 aacatcacac accgttcagc aacctgcggt gcggagagtc gcccctgccc ttgtgcgcca
     1261 atgagcgggt aaatggcggg atcgacctgt tttttgcttt tacgcccttt ctgaccataa
     1321 agatagaaac cccgaccatt ttttctgcct ttgcgatcgt cgttcaaaat tgaagaaaca
     1381 acatttgcag gcgcgctaaa acgttctcca taagcggctt ccagtacagg aataatttta
     1441 gtcccggtgt cgattcctac ctcatccaaa agttggattg gacctaccgg aaaaccaaat
     1501 ttcactagcg cggcatcaat gtgctctacc cgttcacctt cggtcagcat gcggatagct
     1561 tcattaatgt aaggcgctaa gatgcgattg acgtaaaacc cggctttgtc acgcacgaca
     1621 atgggcgttt tgccctgttt tttcgccagt tttaccgtag tggcgatggt ttgcgctgat
     1681 gtacccgcat gaggaataat ctccaccagc ggcatttttt ccaccggact gaagaaatgc
     1741 aggccgataa cttgctcagg tcgcgtggcg tgagcggcga tatcaccaat cggcaaagat
     1801 gacgtattcg aagcaaagat ggtatgagcg gcgcaatttt gctccacttc cgccaccatc
     1861 tgttgtttta attcgagatt ttcaaacacc gcttcaataa tcagatcgcg atgggcaaag
     1921 ccgcgatagt ccgtcgttcc ggagattaat gccagctgtt tgtcacgttc gctggctttg
     1981 agatgacgac ggcgaacttt gccctccagc tgatcccaac tgtacttcag cgcatgattt
     2041 atgccctgcg ggttgatatc tttaattctg accggaagcc ccgctttaca agcagtgaca
     2101 taagcaatac cgccgcccat caagccacca cctaaaattc ccacgctgtt taatggcgca
     2161 ggcggtgcat cactaccggg atctttcttc acttccgtac tggcaaaaaa gatactacgc
     2221 agcgcctgcg attgtggcgt catcgccagt tcgccaaacg cccgagcttc ggcgtcataa
     2281 ccgctgctgg tgccctgcgc taatcccgtt tcaacaacct ccaggatgcg ttctgtcgcc
     2341 ggataattgc cttgagtttt gtgttctgtt ttcttaccga ccattttgaa cagcagcgca
     2401 cgacctaacg gccccgccag aatacgctcg cgtacaggta gagggcggga agatgggcga
     2461 tccttcttcg ccagctcaac agcgacttcc agcaaaatgg agtgcggaac aacgtcatcc
     2521 accagcccca gctttaatgc ctgtttcgcc cgaagttgtt ttccggtgag gatcatctct
     2581 aatgctgtgc tgacgcctat cagacgcggt aaacgctggg tgccgcctga accgggtaac
     2641 aatccaagtt gtacttcagg caaaccgagc accgttttag gatcgtcagt acaaacgcga
     2701 ccgtggcacg ccagcgccaa ctccagccca ccacccaggc aagcgccatg aatagccgcg
     2761 ataaccggaa tgggcaaagc atgaatctcc gccatcaact gttggccctg ccgcgccagt
     2821 gcttccgctt cttgcgccgt tttgcagttg ccgatcatgt tgatgtctgc gccagcaatg
     2881 aagttgtccg gtttagcgga gacaaacacc acgcctcgca actctttgtt ttcacggagt
     2941 tgcttaataa tggcgcgcac ctgcgaggca aactccgcct tcagggtatt cattttctca
     3001 cccggtacgt cgatggtgat aacggcaatg ttgtccagac gaacattaag ggtaaacgct
     3061 gatgtcattt ccattattcc gcctccagaa ccattgccgc gccaagccca ccggcagcac
     3121 aggcggtaac taaaccaaat ccaccgccgc gacggcgaag ttcatgcaat gtctgggtaa
     3181 tcatccgtgc gccggtcgcc gcgaagggat gtccgtaagc aatcgaaccg ccaagcacgt
     3241 taaatttgct atcgtccact tcgccagtgg catgtgcacg ccccagtact tcacgagcaa
     3301 aacgttcact acccagcaac tgaatattcg ccagtgtctg agctgcaaag gcttcgtgca
     3361 tatcgatcaa tgtcagatcg ctcattgtca aaccggcacg ttccagcgcc agcggtgttg
     3421 accaggccgg accgagcaac atgtcctgcc agacatcaat cgcagtaaat gcgtagctgc
     3481 gcagataccc cagcggcacc agccctaatt ctttcgcccg ggattcagtc atcaggatca
     3541 ccgctgccgc gccatcggtc agcggcgtac tgtttgccgc cgttaccgtt ccgtgtttgc
     3601 gatcaaacgc cgggcgcagc tttgcgtaat cggcaagcga ggaattaccg cgaatattgt
     3661 tgtcttcgac aagcggttgt ttataaggag ggataaaggc agtcatcacc tcttctttga
     3721 gttttccgtc tgaccatgcc tgagcggcac gctgatgcga acggtgcgct aatgcatctt
     3781 gctgttctcg ggtgatgccg taggttttcg ccatttgttc ggcggtgtcg cccatccgca
     3841 agccagtaga atattctgct accgcaggcg gtacgggcat taagtcgcgc aaacgcaggc
     3901 gagagaagag tttcagtcgc tggctcatgg ttcgagcttt gttgacatca accagcacgc
     3961 gcgccagttt tttactgacg ccaattggca atacggaaga ggaatctgcc ccaccggcaa
     4021 tccccgctcg gatagttccc gccatcaggc tttctgcgac gtttgcaacc gcctggaaac
     4081 tggtagcgca agcgcggctg acgctgtaag catcggtatg cacattcatt ccggtaccga
     4141 gaacaatttc acgcgcaatg ttgggggctt caggcatttg tacgacctga ccaaagacca
     4201 gctgttcaat cacttcagcg gggatctcgc tgcgtgccag cagttcgcct accaccatct
     4261 tccctaaatc aaccgcggga atgccatgaa aagccgtcgc ctggcgggca aaaggcgtac
     4321 gtaaaccgct aacaatggcg atacgatcgc cctggcgggt aaccagcggt aaaacctgac
     4381 ccataacact cccctgtaaa aaaataaata aagtggtctg acctgattat agtcttaacc
     4441 atttttttac atttagccaa gcggagaaaa aggaaagtgg gagctatgac acagtgaaga
     4501 caggagaaag aaaagaaaac gcccctgcca gcaactgaca ggggcgtacg tacccgagag
     4561 gaattaacgc agacccagct ggaagatcag catttcagct tcgcaggcaa aagtgaaatc
     4621 gatatccagg cgcacaccgt cagactcttc agtgaaagtc ggggtgattt tacacggttc
     4681 ggattccacg ctacgggctt tttcagtcag cgccgccagc gtttgttctg cttctgcgcg
     4741 gcttgcaaac acgcggctgt aagacgcggt gcagtcggag ttgtccataa tggtgccaac
     4801 atccatacag cagcaaaccg gggtttcatc agcactacat ttactcatcg ttgatttcct
     4861 ctgtatgtgc acccaaggtg ccagataaac gttgtggata ttttacgctt ccggaaagtg
     4921 ctgctccagt tgttaattct gcaaaatcgg ataagtgacc gaaatcacac ttaaaaatga
     4981 tctaaaacaa aattcacccg aatccgcgag tgcgcaacct ccaaattttg ccagctggat
     5041 cgcgtttctt agatcatatt tgaaaaaaga tggaaacata cttgcaacat tccagctggt
     5101 ccgacctata ctctcgccac tggtctgatt tctaagatgt acctcagacc ctacacttcg
     5161 cgctcctgtt acagcacgta acatagtttg tataaaaata aatcattgag gttatggtca
     5221 tgagccagaa aaccctgttt acaaagtctg ctctcgcagt cgcagtggca cttatctcca
     5281 cccaggcctg gtcggcaggc tttcagttaa acgaattttc ttcctctggc ctgggccggg
     5341 cttattcagg ggaaggcgca attgccgatg atgcaggtaa cgttagccgt aaccccgcat
     5401 tgattaccat gtttgaccgc ccgacatttt ctgcgggtgc ggtttatatt gacccggatg
     5461 tgaatatcag cggaacgtct ccgtctggtc gtagcctgaa agccgataac atcgcgccta
     5521 cggcatgggt tccgaacatg cactttgttg caccgattaa cgaccaattt ggttggggcg
     5581 cttctattac ctctaactat ggtctggcaa cagagtttaa tgatacttat gcaggcggct
     5641 ctgtcggggg tacaactgac cttgaaacca tgaacctgaa cttaagcggt gcgtatcgct
     5701 taaataatgc atggagcttt ggtcttggtt tcaacgccgt ctacgctcgc gcgaaaattg
     5761 aacgtttcgc aggcgatctg gggcagttgg ttgctggtca gattatgcaa tctcctgccg
     5821 ggcaaactcc tcaagggcaa gcattggcag ctaccgccaa cggtatcgac agtaatacca
     5881 aaatcgctca tctgaacggt aaccagtggg gctttggctg gaacgccgga atcctgtatg
     5941 aactggataa aaataaccgc tatgcactga cctaccgttc tgaagtgaaa attgacttca
     6001 aaggtaacta cagcagcgat cttaatcgtg cgtttaataa ctacggtttg ccaattccta
     6061 ccgcgacagg tggcgcaacg caatcgggtt atctgacgct gaacctgcct gaaatgtggg
     6121 aagtgtcagg ttataaccgt gttgatccac agtgggcgat tcactatagc ctggcttaca
     6181 ccagctggag tcagttccag cagctgaaag cgacctcaac cagtggcgac acgctgttcc
     6241 agaaacatga aggctttaaa gatgcttacc gcatcgcgtt gggtaccact tattactacg
     6301 atgataactg gaccttccgt accggtatcg cctttgatga cagcccagtt ccggctcaga
     6361 atcgttctat ctccattccg gaccaggacc gtttctggct gagtgcaggt acgacttacg
     6421 catttaataa agatgcttca gtcgacattg gtgtttctta tatgcacggt cagagcgtga
     6481 aaattaacga aggcccatac cagttcgagt ctgaaggtaa agcctggctg ttcggtacta
     6541 actttaacta cgcgttctga taacgcgttc gcctggataa agtcacctgc atagcaggtg
     6601 actttaactc ccccacttca ccgaaagtag tgtcctcatt gcttacctcc tgagttttgc
     6661 aaacagcctg ttggcagctt gccctttcaa atcaataagc ggtatccaca gacaaacctg
     6721 aagggaaagg catattttca ggcgttctgc tcgtccttct caaagagttt acttttctgc
     6781 atttccagga tactcccccc cctggctatt gtgcgctcat acactcaaat taaagatagg
     6841 ttcta
//
LOCUS       DAPOAV010000154         6647 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.155, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000154 DAPOAV010000000
VERSION     DAPOAV010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6647
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.155"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            1..332
                     /locus_tag="RN951_004207"
                     /pseudo
     CDS             1..332
                     /locus_tag="RN951_004207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005151214.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="colicin-10"
     gene            450..986
                     /locus_tag="RN951_004208"
     CDS             450..986
                     /locus_tag="RN951_004208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005144371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin"
                     /protein_id="HDX2529109.1"
                     /translation="MKDAVDATVSFYQTLTEKYGEKYSKMAQELADKSKGKKIGNVNE
                     ALAAFEKYKDVLNKKFSKADRDAIFNALASVKYDDWAKHLDQFAKYLKITGHVSFGYD
                     VVSDILKIKDTGDWKPLFLTLEKKAADAGVSYVVALLFSLLAGTTLGIWGIAIVTGIL
                     CSYIDKNKLNTINEVLGI"
     gene            complement(983..1324)
                     /locus_tag="RN951_004209"
     CDS             complement(983..1324)
                     /locus_tag="RN951_004209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin E1 immunity protein"
                     /protein_id="HDX2529110.1"
                     /translation="MSLRYYIKNILFGLYCTLIYIYLITKNSEGYYFLVSDKMLYAIV
                     ISTILCPYSKYAIEYIAFNFIKKDFFERRKNLNNAPVAKLNLFMLYNLLCLVLAIPFG
                     LLGLFISIKNN"
     gene            1372..1509
                     /locus_tag="RN951_004210"
     CDS             1372..1509
                     /locus_tag="RN951_004210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001405930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin release lysis protein"
                     /protein_id="HDX2529111.1"
                     /translation="MRKRFFVGIFAINLLVGCQANYIRDVQGGTIAPSSSSKLTGIAV
                     Q"
     gene            complement(2536..2727)
                     /locus_tag="RN951_004211"
     CDS             complement(2536..2727)
                     /locus_tag="RN951_004211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="HDX2529112.1"
                     /translation="MTKQEKTALNMARFIRSQTLTLLEKLNELDADEQADICESLHDH
                     ADELYRSCLARFGDDGENL"
     gene            2791..3114
                     /locus_tag="RN951_004212"
     CDS             2791..3114
                     /locus_tag="RN951_004212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HDX2529113.1"
                     /translation="MLTIRVTDDEHARLLERCEGKQLAVWMRRVCLGEPVARSGKLPT
                     LAPPLLRQLAAIGNNLNQTARKVNSGQWSSGDRVQVVAALMAIGDELRRLRLAVREQG
                     ARDDS"
     gene            3056..3814
                     /locus_tag="RN951_004213"
                     /pseudo
     CDS             3056..3814
                     /locus_tag="RN951_004213"
                     /inference="COORDINATES: protein motif:HMM:NF015397.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            3792..4310
                     /locus_tag="RN951_004214"
     CDS             3792..4310
                     /locus_tag="RN951_004214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001447511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mobilization protein MbeB"
                     /protein_id="HDX2529114.1"
                     /translation="MSNLLQTGAEFEKKLKERAESTEKMLNNEFRRLGESVSEAVTSN
                     ETKIRDAIALFTASTEESLEKHREGVKEAMMQHRRDVLKLAGNTGMMLLGIVFLLFTA
                     SGGTLWYLGGRIQANLEEIRKQEETLQKLNAKTWGVEFVQDGNRKFLVLPYGKSAEVI
                     PFQGKEWVHLKE"
     gene            4317..4550
                     /locus_tag="RN951_004215"
     CDS             4317..4550
                     /locus_tag="RN951_004215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="HDX2529115.1"
                     /translation="MTELETHLLNALEQLQQDYMQRLSEWESAFVELQKMFSLTQRDN
                     AMLNERVMQLSQQVQHLSEQTERLSQLYSENWR"
     gene            complement(4868..5287)
                     /locus_tag="RN951_004216"
     CDS             complement(4868..5287)
                     /locus_tag="RN951_004216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Exc2 family lipoprotein"
                     /protein_id="HDX2529116.1"
                     /translation="MRRTGNKLCLIAMITATVALTACTPKGSVEQHTRHYVYASDDGF
                     DPNFSTQKADTTRMMVPFFRQFWDMGAKDKATGKSRSDVQQRIQQFHSQEFLNSLRGT
                     TQFAGTDYRSKDLTPKKSRLLADTISAVYLDGYEGRQ"
     gene            complement(5368..5805)
                     /locus_tag="RN951_004217"
     CDS             complement(5368..5805)
                     /locus_tag="RN951_004217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001405929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="entry exclusion protein 1"
                     /protein_id="HDX2529117.1"
                     /translation="MGHCHFMAWHTLRDALKMTGRSRSQFYRDMRAGLVSYRTGRDGR
                     REFETSELIRAYGELKQNETPERHSEGHAENPHDQQTERILRELNELKQCLTLMLEDK
                     QAQDMDRRRQEAEREQLQNEIAQLRQALELEKKRGFWSRLFGR"
     gene            6065..>6647
                     /gene="cea"
                     /locus_tag="RN951_004218"
     CDS             6065..>6647
                     /gene="cea"
                     /locus_tag="RN951_004218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pore-forming bacteriocin colicin E1"
                     /protein_id="HDX2529118.1"
                     /translation="METAVAYHKDGVPYDDKGQVIITLLNGTPDGSGSGGGGGKGGSK
                     SESSAAIHATAKWSTAQLKKTQAEQAARAKAAAEAQAKAKANRDALTQRLKDIVNEAL
                     RHNASRTPSATELAHANNAAMQAEAERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEI
                     EREKAETERQLKLAEAEEKRLAALSEEAKAVEIA"
BASE COUNT         1757 a         1423 c         1803 g         1664 t
ORIGIN      
        1 aaaaaaaact ttctgctgca caatctgaag tggtgaaaat ggatggagag attaagactc
       61 tcaattctcg tttaagctcc agtatccatg cccgtgatgc agaaatgaaa acgctcgctg
      121 gaaaacgaaa tgaactggct caggcatccg ctaaatataa agaactggat gagctggtca
      181 aaaaactatc accaagagcc aatgatccgc ttcagaaccg tccttttttt gaagcaacca
      241 gacgacgggt tggggccggt aagattagag aagaaaaaca aaaacaggta acagcatcag
      301 aaacacgtat taaccggata aatgctgata taactcagat ccagaaggct atttctcagg
      361 tcagtaataa tcgtaatgcc ggtatcgctc gtgttcatga agctgaagaa aatttgaaaa
      421 aagcacagaa taatctcctt aattcacaga ttaaggatgc tgttgatgca acagttagct
      481 tttatcaaac gctgactgaa aaatatggtg aaaaatattc gaaaatggca caggaacttg
      541 ctgataagtc taaaggtaag aaaatcggca atgtgaatga agctctcgct gcttttgaaa
      601 aatacaagga tgttttaaat aagaaattca gcaaagccga tcgtgatgct atttttaatg
      661 cgttggcatc ggtgaagtat gatgactggg ctaaacattt agatcagttt gccaagtact
      721 tgaagattac ggggcatgtt tcttttggat atgatgtggt atctgatatc ctaaaaatta
      781 aggatacagg tgactggaag ccactatttc ttacattaga gaagaaagct gcagatgcag
      841 gggtgagtta tgttgttgct ttacttttta gcttgcttgc tggaactaca ttaggtattt
      901 ggggtattgc tattgttaca ggaattctat gctcctatat tgataagaat aaacttaata
      961 ctataaatga ggtgttaggg atttaattat tctttattga tataaaaagt cctagcaatc
     1021 caaatgggat tgctaggacc aaacaaagta gattatatag cataaatagg tttaattttg
     1081 ctacgggggc gttatttagg ttttttcttc tttcgaaaaa atctttcttt atgaagttaa
     1141 aagctatgta ttcaatagca tattttgaat atggacatag aatagtgctt atcactattg
     1201 catatagcat cttatctgac acaaggaaat aatacccttc gctgtttttt gttataaggt
     1261 atatatatat aagtgtgcag tacaggccaa ataaaatatt ttttatgtag tatcttaagc
     1321 tcataaatta aacctcgcca tatattcttt tcattttata aggatcgagt tatgaggaaa
     1381 agattttttg tgggaatatt cgcgataaac ctccttgttg gatgtcaggc taactatata
     1441 cgtgatgttc agggagggac catcgcacca tcctcctctt ctaaactgac ggggatcgcg
     1501 gttcagtaga aaagattaaa ggatcttctt gagatccttt ttttctgcgc gtaatctgct
     1561 gcttgcaaac aaaaaaacca ccgctaccaa cggtggtttg tttgccggat caagagctac
     1621 caactctttt tccgaaggta actggcttca gcagagcgca gataccaaat actgtccttc
     1681 tagtgtagcc gtagtcgggc cactacttca agaactctgt agcaccgttt gtgccatcat
     1741 cgctctgcta atccggttac cagtggctgc tgccagtggc gttaaggcgt gccttaccgg
     1801 gttggactca agacgatagt taccggataa ggcgcagcgg tcgggctgaa cggggggttc
     1861 gtgcacacag cccagcttgg agcgaacgac ctacaccgaa ctgagatacc aacagcgtga
     1921 gctatgagaa agcgccacgc ttcccgaagg gagaaaggcg gacaggtatc cggtaagcgg
     1981 cagggtcgga acaggagagc gcacgaggga gcttccaggg ggaaacgcct ggtatcttta
     2041 tagtcctgtc gggtttcgcc acctctgact tgagcgtcta tttttgtgat gctcgtcagg
     2101 ggggcggagc ctatggaaaa acgcctgcta cgtggccttc ttcctgttcc tggtcttttg
     2161 ctcacatgtt ctttccggcc ttatcccctg attctgtgga taactgtgtt accgtttttg
     2221 tgtgagtcag taccgctcgc cgcagtcgaa cgaccgagcg tagcgagtca gtgagcgagg
     2281 aagcggaaaa gcgcctggac gtgcattttc tccttacgca tctgtgcggc atttcacacc
     2341 cggcatggcg tacttttcat acaatccgca ctgatgccgc atggttaagc cagtatacac
     2401 tccgctatcg ctacgtgact gggtcagggc tgcgccccga cacccgctaa aacctgctga
     2461 cgcgccctga cgggcttgtc agctcccggc atccgctcac agacaagctg tgaccgtctc
     2521 cgggagctgc atgtgtcaga ggttttcacc gtcatccccg aaacgtgcga ggcagctgcg
     2581 gtaaagctca tcggcgtggt cgtgaagcga ttcacaaata tcggcctgtt catctgcgtc
     2641 cagttcgttg agcttctcca gcagcgttaa tgtctggctt ctgataaagc gggccatgtt
     2701 aagggcggtt ttttcctgtt tagtcactga tgcctccgtg taagggggat ttctgttcat
     2761 ggggtaatga taccgatgaa acgcgagagg atgctcacaa tacgggttac tgatgatgaa
     2821 catgcccggt tacttgaacg ctgtgagggt aaacaactgg cggtatggat gcggcgggtc
     2881 tgcctggggg agccggttgc ccgttccgga aaactgccga cactggcacc gccgttactg
     2941 cgtcagctgg ccgccatcgg aaataacctg aatcagacag cccgtaaggt gaacagcggg
     3001 cagtggtctt ccggtgaccg ggttcaggtg gtggccgcac tgatggccat cggggatgag
     3061 ctgcgccggc tgcgtctggc tgtcagggaa cagggggcgc gggatgatag ttaaatttca
     3121 tgccagggga aaaggtggtg gcagtggtcc ggttgattac ctgctgggga gggagcgtaa
     3181 ccgcgaaggc gcaacggtgc ttcagggtaa tccggaagaa gtccgggaac tcatcgatgc
     3241 cacgccattt gcgaagaaat acacgtccgg tgttctgtcg ttcgcggaga aggagctgcc
     3301 gccgggagga cgtgaaaaag tgatggcgag ctttgagcgt gtactgatgc ccggtctcga
     3361 aaaaaatcag tacagcatcc tgtgggtgga gcaccaggac aagggacggc ttgagctgaa
     3421 ttttgtcatt ccgaacatgg agctacagac cggaaaacgc ctccagccgt actacgaccg
     3481 cgcagacagg cctagaattg atgcctggca gacgctggta aatcaccatt acgggctgca
     3541 tgacccgaac gccccggaga accgcaggac gctgacactc cctgataacc tgcctgaaac
     3601 gaaacaggcg cttgctgagg gcgtcacgcg aggtatagat gcactttacc atgccggaga
     3661 gataaaaggc cgtcaggatg tgattcaggc gctcactgag gcggggctgg aagtggtcag
     3721 ggtgacgcga agcagtatca gcattgcaga tccgaacggc gggaagaata tcaggctgaa
     3781 aggagcattt tatgagcaat cttttgcaga cgggcgcgga gttcgagaaa aagctgaaag
     3841 agagagccga atctacagag aaaatgctga acaacgagtt caggaggctc ggcgaatctg
     3901 taagcgaggc tgtgacatca aacgagacga aaatcagaga cgctatagcc ctgttcacag
     3961 cctcgacaga ggaatcgctg gaaaaacacc gggaaggggt gaaagaggcg atgatgcagc
     4021 acaggaggga cgtgttaaag ctggcaggga atacgggcat gatgttactg gggatagtct
     4081 ttctcctgtt taccgcgagt ggcgggacgc tctggtatct tggagggagg atacaggcga
     4141 acctggaaga aatcaggaag caggaagaga cattgcagaa actgaacgcg aagacatggg
     4201 gcgtggagtt tgtgcaggac gggaacagga aattccttgt ccttccgtac gggaaatcag
     4261 cggaggtgat tccctttcag gggaaagagt gggtacatct gaaggagtga cacagagtga
     4321 cagagctgga aacacatttg ctgaacgcct tagagcagct gcaacaggac tatatgcagc
     4381 ggctgagcga atgggagagc gccttcgtgg aattgcagaa gatgttttcg cttacgcaac
     4441 gggacaacgc gatgctgaac gagcgggtca tgcagttgag tcagcaggtg cagcacttga
     4501 gcgagcagac agaacgcttg agccagttat acagcgagaa ctggagataa gagaggaacg
     4561 gctgatacag gagcgcgaac atgtgttatc cctggaacgg gagcgtcagc cggaaataca
     4621 ggaacgcacg ctggatggcc cttcgctggg atggtgaaac catgaaaaat ggcagcttca
     4681 gtggattaag tgggggtaat gtggcctgta ccctctggtt gcataggtat tcatacggtt
     4741 aaaatttatc aggcgcgatc gcggcagttt ttcgggtggt ttgttgccat ttttacctgt
     4801 ctgctgccgt gatcgcgctg aacgcgtttt agcggtgcgt acaattaagg gattatggta
     4861 aatccactta ctgtctgccc tcgtagccat cgagataaac cgcagaaatc gtgtcagcca
     4921 gcagcctgga ttttttcggg gtaaggtctt tgctgcggta atcagtaccc gcaaattgag
     4981 ttgtgccccg gagtgagttt aaaaattcct ggctgtgaaa ctgctgaatg cgttgttgca
     5041 catcactccg tgattttcct gtcgctttat ctttagctcc catatcccag aactgccgaa
     5101 aaaaaggcac catcattcgt gttgtgtcgg ctttttgggt ggaaaagttg ggatcaaaac
     5161 cgtcatcaga agcatatacg taatgccggg tatgttgttc cacgctgccc tttggggtac
     5221 aggctgtgag agctactgtt gctgttatca tggcgataag acaaagtttg tttccggtac
     5281 gtctcatgag tgtctcccta ccttaaagta tttattctcg gtgagttatt atccgaagac
     5341 tattttatca tcagtctctg acagcgttca gcgaccgaac aacctggacc agaatccccg
     5401 tttcttttcc agttccagtg cctgcctgag ctgggctatc tcattttgta gctgttcccg
     5461 ttctgcttcc tggcgtctgc gatccatatc ctgtgcctgt ttatcctcaa gcatcagcgt
     5521 caggcattgt ttcagctcat tcagttcccg gagaatgcgt tctgtctgct gatcatgtgg
     5581 attttctgca tgtccctcac tgtgcctttc tggtgtctca ttctgcttta attcgccgta
     5641 tgcccggatc agttcactgg tttcaaactc ccgtcgtccg tccctgccgg tacggtaact
     5701 gacaaggcct gcgcgcatat cacggtaaaa ctgtgaacgc gatctgcctg tcatttttag
     5761 tgcgtcccgg agtgtgtgcc atgccataaa gtgacagtgt cccatagatg tctcatctca
     5821 tagtttcagt aaaacataat gaggtctgag aacggtaatg tttgtgctgg tttttgtggc
     5881 atcgggcgag aatagcgcgt ggtgtgaaag actgtttttt tgatcgtttt cacaaaaatg
     5941 gaagtccaca gtcttgacag ggaaaatgca gcggcgtagc ttttatgctg tatataaaac
     6001 cagtggttgt atgtacagta tttattttta acttattgtt ttaaaagtca aagaggattt
     6061 tataatggaa accgcggtag cgtaccataa agatggtgtt ccttatgatg ataagggaca
     6121 ggtaattatt actcttttga atggtactcc tgacgggagt ggctctggcg gcggaggtgg
     6181 aaaaggaggc agtaaaagtg aaagttctgc agctattcat gcaactgcta aatggtctac
     6241 tgctcaatta aagaaaacac aggcagagca ggctgcccgg gcaaaagctg cagcggaagc
     6301 acaggcgaaa gcaaaggcaa acagggatgc gctgactcag cgcctgaagg atatcgtgaa
     6361 tgaggctctt cgtcacaatg cctcacgtac gccttcagca acagagcttg ctcatgctaa
     6421 taatgcagct atgcaggcgg aagcagagcg tttgcgcctt gcgaaagcag aagaaaaagc
     6481 ccgtaaagaa gcggaagcag cagaaaaggc ttttcaggaa gcagaacaac gacgtaaaga
     6541 gattgaacgg gagaaggctg aaacagaacg ccagttgaaa ctggctgaag ctgaagagaa
     6601 acgactggct gcattgagtg aagaagctaa agctgttgag atcgccc
//
LOCUS       DAPOAV010000155         6556 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.156, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000155 DAPOAV010000000
VERSION     DAPOAV010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6556
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.156"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(40..1407)
                     /gene="ydfJ"
                     /locus_tag="RN951_004219"
     CDS             complement(40..1407)
                     /gene="ydfJ"
                     /locus_tag="RN951_004219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000582800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter YdfJ"
                     /protein_id="HDX2529119.1"
                     /translation="MTIEKHERSTKDLVKAAVSGWLGTALEFMDFQLYSLGAALVFHE
                     IFFPESSTAMALILAMGTYGAGYVARIVGAFIFGKMGDRIGRKKVLFITITMMGICTT
                     LIGVLPTYAQIGVFAPILLVTLRIIQGLGAGAEISGAGTMLAEYAPKGKRGIISSFVA
                     MGTNCGTLSATAIWAFMFFILSKEELLAWGWRIPFLASVVVMVFAIWLRMNLKESPVF
                     EKVNDSNQPTAKPAPAGSMFQSKSFWLATGLRFGQAGNSGLIQTFLAGYLVQTLLFNK
                     AIPTDALMISSILGFMTIPFLGWLSDKIGRRIPYIIMNTSAIVLAWPMLSIIVDKSYA
                     PSTIMVALIVIHNCAVLGLFALENITMAEMFGCKNRFTRMAISKEIGGLIASGFGPIL
                     AGIFCTMTESWYPIAIMIMAYSVIGLISALKMPEVKDRDLSALEDAAEDQPRVVRAAQ
                     PSRSL"
     gene            complement(1465..2484)
                     /locus_tag="RN951_004220"
     CDS             complement(1465..2484)
                     /locus_tag="RN951_004220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn-dependent oxidoreductase"
                     /protein_id="HDX2529120.1"
                     /translation="MKSILIEKPNQLAIVEREIPTPSAGEVRVKVKLAGICGSDSHIY
                     RGHNPFAKYPRVIGHEFFGVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNV
                     CTTLAVLGVHADGGFSEYAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQPTE
                     NDTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADWAINNSQTPL
                     GEIFTEKGIKPTLIIDAACHPSILKEAVTLASPAARIVLMGFSSEPSEVIQQGITGKE
                     LSIFSSRLNANKFPIVIDWLSKGLIKPEKLITHTFDFQHVADAISLFEQDQKHCCKVL
                     LTFSE"
     gene            complement(2496..3710)
                     /gene="rspA"
                     /locus_tag="RN951_004221"
     CDS             complement(2496..3710)
                     /gene="rspA"
                     /locus_tag="RN951_004221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="starvation-sensing protein RspA"
                     /protein_id="HDX2529121.1"
                     /translation="MKIVKAEVFVTCPGRNFVTLKITTEDGITGLGDATLNGRELSVA
                     SYLQDHLCPQLIGRDAHRIEDIWQFFYKGAYWRRGPVTMSAISAVDMALWDIKAKAAN
                     MPLYQLLGGASREGVMVYCHTTGHSIDEALDDYARHQELGFKAIRVQCGIPGMKTTYG
                     MSKGKGLAYEPATKGQWPEEQLWSTEKYLDFMPKLFDAVRNKFGFNEHLLHDMHHRLT
                     PIEAARFGKSIEDYRMFWMEDPTPAENQECFRLIRQHTVTPIAVGEVFNSIWDCKQLI
                     EEQLIDYIRTTLTHAGGITGMRRIADFASLYQVRTGSHGPSDLSPVCMAAALHFDLWV
                     PNFGVQEYMGYSEQMLEVFPHNWTFDNGYMHPGDKPGLGIEFDEKLAAKYPYEPAYLP
                     VARLEDGTLWNW"
     gene            complement(3916..4242)
                     /locus_tag="RN951_004222"
     CDS             complement(3916..4242)
                     /locus_tag="RN951_004222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfA family protein"
                     /protein_id="HDX2529122.1"
                     /translation="MIKTTLLFFATALCEIIGCFLPWLWLKRNASIWLLLPAGISLAL
                     FVWLLTLHPAASGRVYAAYGGVYVCTALMWLRVVDGVKLTLYDWTGALIALCGMLIIV
                     AGWGRT"
     gene            4377..4718
                     /locus_tag="RN951_004223"
     CDS             4377..4718
                     /locus_tag="RN951_004223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1283 family protein"
                     /protein_id="HDX2529123.1"
                     /translation="MKITLSKRIGLLAILLPCALALSTTVHAETNKLVIESGDSAQSR
                     QHAAMEKEQWNDTRNLRQKVNKRTEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRC
                     LDRRTGRVITP"
     gene            4753..5313
                     /gene="speG"
                     /locus_tag="RN951_004224"
     CDS             4753..5313
                     /gene="speG"
                     /locus_tag="RN951_004224"
                     /EC_number="2.3.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine N1-acetyltransferase"
                     /protein_id="HDX2529124.1"
                     /translation="MPSAHSVKLRPLEREDLRYVHQLDNNASVMRYWFEEPYEAFVEL
                     SDLYDKHIHDQSERRFVVECDGEKAGLVELVEINHVHRRAEFQIIISPEYQGKGLATR
                     AAKLAMDYGFTVLNLYKLYLIVDKENEKAIHIYRKLGFSVEGELMHEFFINGQYRNAI
                     RMCIFQHQYLAEHKTPGQTLLKPTAQ"
     gene            complement(5316..6026)
                     /locus_tag="RN951_004225"
     CDS             complement(5316..6026)
                     /locus_tag="RN951_004225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416102.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfC family lipoprotein"
                     /protein_id="HDX2529125.1"
                     /translation="MKYKLLPCLLAIFLTGCDRTEVTLSFTPEMASFSNEFDFDPLRG
                     PVKDFTQTLMDEQGEVTKRVSGTLSEEGCFDSLELLDLENNTVVALVLDANYYRDAET
                     LEKRVRLQGKCQLAELPSAGVSWETDDNGFVIKASSKQMQMEYRYDDQGYPLGKTTKS
                     NDKTLSVSATPSTDPIKKLDYTAVTLLNNQRVGNVKQSCEYDSHANPVDCQLIIVDEG
                     VKPAVERVYTIKNTIDYY"
     gene            6134..6439
                     /locus_tag="RN951_004226"
     CDS             6134..6439
                     /locus_tag="RN951_004226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416103.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1161 domain-containing protein"
                     /protein_id="HDX2529126.1"
                     /translation="MKLSTCCAALLLALASPAVLAAPGSCERIQSDISQRIINNGVPE
                     SSFTLSIVPNDQVDQPDSQVVGHCANDTHKILYTRTTSGNVSAPAQSSQDGAPAEPQ"
BASE COUNT         1823 a         1658 c         1410 g         1665 t
ORIGIN      
        1 ataaaaatcc cctctccggt aagagaaggg attaagggtt tacagacttc tggaaggttg
       61 cgcagctctt acaacacgcg gttgatcttc cgcagcgtct tccagcgcac ttaaatcacg
      121 gtctttcacc tctggcattt tcagcgcaga gattaaacca atcactgaat atgccatgat
      181 cataatggcg atcggatacc aggattccgt catggtgcag aaaatacccg ccaggatagg
      241 accaaaaccg gaagcgataa gaccaccaat ttctttagaa atagccatcc gggtaaagcg
      301 gtttttacag ccgaacattt ctgccatggt aatgttttcc agagcaaata atcccagcac
      361 cgcacagtta tgaatcacaa tcagtgcaac cataatggtg ctcggggcat agcttttatc
      421 tacaatgata gaaagcattg gccatgccag cacaatcgcg gaggtattca taataatata
      481 cgggatccgg cgaccaattt tatcggataa ccaaccaagg aacggaatgg tcataaagcc
      541 gagaatcgaa ctgatcatca atgcatctgt tggaattgct ttgttaaaca ataacgtctg
      601 cactaaatag cctgcaagga aagtctgaat taacccggag ttacccgcct gaccaaaacg
      661 cagccctgtt gccagccaga aggatttgct ctggaacatg ctaccagcag gtgcaggttt
      721 tgctgtcggt tggttactgt cgttaacctt ctcaaagacc gggctttctt tcagattcat
      781 acgcaaccag atagcaaaga ccatcacgac aacactcgcc aggaacggta tacgccatcc
      841 ccacgccagc agttcctctt tactgagaat gaagaacata aaggcccaga ttgccgttgc
      901 gctcaaggtt ccgcagttag ttcccatagc cacaaatgag gagataattc cgcgcttacc
      961 ttttggcgca tattccgcca gcatcgtacc ggcaccggaa atttccgcac ctgcacccaa
     1021 cccctgaata atacgcaacg tcaccagcaa gatgggtgca aaaacaccaa tctgtgcata
     1081 ggtcggtaac acaccaatta aggtggtaca gatccccatc atggtgatgg taataaagag
     1141 cactttttta cgccctattc tgtcgcccat tttgccgaaa ataaatgctc cgacaatacg
     1201 cgccacataa cctgcaccgt aggttcccat tgccagaatt aacgccattg ccgttgatga
     1261 ttcaggaaaa aatatttcat gaaacactaa cgctgcgccg agcgaatata actggaaatc
     1321 cataaattca agcgcagtgc ccagccatcc cgatactgct gctttcacca aatccttagt
     1381 gcttctttcg tgtttttcta ttgtcataat ggttatctct aaaaaagagg taagatgcgt
     1441 actacttact cgccgttatt ggtattattc agaaaaagtg agtaagactt tgcagcaatg
     1501 tttttgatcc tgttcaaata aactaatggc atcagcaaca tgctggaaat caaacgtatg
     1561 ggtaattaat ttttctggtt taattaaccc tttacttaac cagtcgataa cgatcgggaa
     1621 tttatttgca tttaagcgtg aagagaaaat agagagttct tttccggtaa ttccttgctg
     1681 aatcacttca gacggttcac tggagaaccc catcaataca atacgtgccg ctggagaagc
     1741 cagcgttacg gcctctttca ggatagaagg atgacaagcc gcatcgataa ttaatgtcgg
     1801 cttgatgcct ttttcagtga aaatctcgcc aagcggtgtc tggctgttat taatcgccca
     1861 gtcagccccg ctctctttcg ctttttccag tcgttcatca atgcgatcgg caacaatcac
     1921 atttttaacg ttatagacgc cttttaatac ctgaacgatc gtcaggccga ttggaccggc
     1981 accataaacc agaacggtat cattttcagt cggttgacca tgtccggtta cgttagccgc
     2041 aatggtaaaa ggttcgatca ttaccgcata ttgatcggcc actgcttcag gaattttcca
     2101 cgcatttttt gccggaacca cggcatattc actgaaacca ccgtcagcgt gcacacctaa
     2161 tacagccagt gtcgtacaaa cgttcggttt acctatagag cacggatagc aatgcccaca
     2221 gctgaccacc ggatcgacag caacacgttc accgactctg gcgctttcca cgccttcacc
     2281 cactgcatca atgacgccaa agaattcatg accaatgacg cgcggatatt tcgcaaaagg
     2341 attatgccca cgataaatat ggctatctga accacaaatt ccggcaagtt tcacttttac
     2401 tcgtacttca cccgctgacg gggtgggtat ttcacgttcg acaatcgcca gttgattcgg
     2461 tttttcaatt aatatgcttt tcattatctt actccttacc agttccacag cgtgccatct
     2521 tccagacgtg cgactggtag ataagcaggt tcatagggat atttcgccgc cagcttttca
     2581 tcgaattcga taccaagacc cggtttgtct cccggatgca tatagccgtt atcgaaagtc
     2641 cagttgtgcg ggaagacttc gagcatttgt tcggaataac ccatgtattc ctggacaccg
     2701 aaattgggga cccacagatc aaagtgcagc gccgcagcca tgcagactgg tgacaaatcg
     2761 gaaggaccgt gtgagccagt acgtacctga tacagcgaag caaaatcggc aatccggcgc
     2821 ataccggtaa ttccgcctgc atgggtcagc gtggtgcgga tataatcgat gagttgctct
     2881 tcaatcagtt gtttgcagtc ccagatgctg ttgaagactt cacccactgc gatgggtgtg
     2941 acggtatgtt ggcgaatgag acggaagcat tcctggtttt ccgcaggcgt cgggtcttcc
     3001 atccagaaca tgcgataatc ttcaatgctt ttaccaaagc gcgccgcttc aataggcgtt
     3061 aagcgatggt gcatgtcatg cagcaaatgt tcattaaaac caaacttgtt acgtaccgcg
     3121 tcaaacaatt tcggcatgaa atcgaggtat ttctccgtcg accacagctg ctcttccggc
     3181 cactgtcctt tggttgcggg ttcataagcc agacctttac ctttcgacat gccgtaggtg
     3241 gttttcatac cagggattcc gcactgcacg cggatggctt tgaatccaag ctcttgatga
     3301 cgggcataat catccagagc ttcatcaata ctgtgaccgg tggtatggca ataaaccatc
     3361 accccttcac gagacgcgcc gccgagtaac tggtaaagcg gcatgttggc agctttggct
     3421 ttaatatccc acagcgccat atcaaccgct gaaatggccg acatcgtaac cggaccgcga
     3481 cgccagtaag cacctttata gaaaaactgc cagatatctt cgatacggtg cgcatcgcga
     3541 ccaataagct gcggacaaag gtgatcctgc aaataagagg ccacggaaag ctcacgtcca
     3601 ttgagggtgg catccccaag gcccgtaata ccgtcctcag tggtgatttt taatgtgacg
     3661 aaattacgcc ccggacaggt aacaaaaact tcagccttta cgatcttcat gttcgattcc
     3721 ttgcatcgct tgtcgtgatg catgaaatct acgcaactga gctactacca tacaagtata
     3781 aagatcgaaa aaagccggag tgatcacaaa aaaaggcgta tatttgcgct gtgaatggtt
     3841 gacaaaagat gaaatagaat accttttgtc agctgacact tcctcttatc ttattgataa
     3901 aatggattta tgttcctacg tgcgccccca gcccgcaaca atgatcaaca tgccgcaaag
     3961 cgcaatcaac gcacccgtcc agtcataaag agtcagtttc acgccatcca caacgcgcag
     4021 ccacatcaac gccgtgcaga cataaacgcc accataagcc gcgtaaacac gcccactcgc
     4081 cgctggatgc aacgttaaca accagacaaa cagcgccagt gaaatccccg ccggaagcaa
     4141 cagccagata ctggcgtttc gttttaacca caaccagggc agaaagcatc caataatttc
     4201 acacagcgca gtagcaaaaa atagtaacgt tgttttaatc atctttgtct cttattgaca
     4261 tcatgtatag ttatagggcg acataatatc atcaatataa acaccctcct ggtacgtttt
     4321 gcgtccgcag tggatggtgt agaatcacct ttaatcattc atacagggaa tgaattatga
     4381 aaatcactct cagcaaacga atcggcctgc tcgctattct gctgccttgc gcactggcat
     4441 tgagcacaac tgttcatgcc gaaactaaca aactggtgat tgagtctggc gacagtgcac
     4501 aaagccgcca gcacgccgct atggaaaaag agcaatggaa tgacacgcgc aatctgcgcc
     4561 agaaagtgaa taaacgcact gaaaaagagt gggataaagc cgacgccgct tttgataacc
     4621 gcgataaatg tgagcaaagc gccaacatca atgcctactg ggagcccaat actttgcgct
     4681 gcctggaccg tcgaactggc cgcgttatta ccccctaacc tgttattgat ttaaggaatg
     4741 taaggacacg ttatgccaag cgcccacagt gttaagctac gcccgctgga gcgtgaagat
     4801 ttacgctatg tacatcaact cgacaataac gccagtgtga tgcgttactg gtttgaggaa
     4861 ccctacgaag cctttgttga actctctgat ctgtatgata agcatattca cgatcagagc
     4921 gaacggcgct ttgtggtgga atgtgacggc gaaaaagccg gtctggtgga gctggtggaa
     4981 attaaccatg ttcatcgccg cgcagaattt cagataatta tctccccgga gtatcagggg
     5041 aaaggtctgg caacccgtgc cgccaaatta gcaatggact atggctttac cgttctcaat
     5101 ctctataagc tgtatctgat cgttgataaa gagaatgaaa aagcgattca catttaccgc
     5161 aagcttggct tttcggttga aggtgaattg atgcacgagt tctttattaa tggtcaatat
     5221 cgtaatgcca ttcgcatgtg tatattccag catcagtatc tggcagagca caaaacaccg
     5281 ggtcagactc tcctgaagcc gaccgcacaa tagcattaat aataatcgat cgtatttttg
     5341 atggtgtaaa cccgttcgac ggcgggtttt actccttcat caacaatgat tagctgacag
     5401 tccaccggat tagcgtgact gtcatattca cagctctgtt ttacattacc aacccgttga
     5461 ttattcagta aagtaaccgc tgtgtaatct aattttttga tcggatccgt tgatggcgtg
     5521 gcgctgacag ataatgtttt gtcgttactt ttcgtggttt tacccagcgg ataaccctga
     5581 tcatcatagc gatattccat ctgcatttgt ttgctgctgg ctttaatcac gaagccatta
     5641 tcatcggttt cccaactcac cccggcagaa ggtaattctg ctagctggca ttttccctgt
     5701 aaacgtactc tcttctccag cgtctcggca tcacggtaat aattggcgtc cagtaccaga
     5761 gcgaccacgg tattattttc cagatccagt aattcgagtg aatcaaaaca gccttcttcc
     5821 gacaaagtcc cagaaacacg tttcgtcact tcaccttgct catccattaa tgtctgagtg
     5881 aaatctttta ccggaccacg cagcggatca aaatcgaatt cattagagaa actggccatc
     5941 tcaggggtaa atgaaagtgt tacctctgtg cggtcacatc ctgtgaggaa tatcgcgagt
     6001 aagcatggta gtaatttgta tttcacaaca gtcaccagag agtagagatg attctcaatc
     6061 atagtagcaa atacagtact ttacacgtta aatgctatgc ttaaagaagt tatcttcgcg
     6121 taaggagctt atgatgaaac tctcaacctg ctgtgccgcg cttctgctcg ccctcgcctc
     6181 acccgcggta ctcgccgcgc cgggatcctg tgagcgcata cagagcgata tatcacagcg
     6241 cattatcaat aatggcgtac ccgaaagcag cttcacgtta agtattgtac ccaatgacca
     6301 ggttgatcag cctgattccc aggtcgtcgg ccattgcgct aatgatacgc ataaaattct
     6361 ctatacccgc accaccagcg gtaacgtctc tgctcccgcg cagtctagcc aggatggcgc
     6421 gcctgccgaa ccgcagtaac acattatcga ctgaacgccg gatatgacaa atccggcgat
     6481 ttgaacatac aacataatcc caccttatta ctcataccct tctattgata tggattaata
     6541 attcttaacc caaaat
//
LOCUS       DAPOAV010000156         6408 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.157, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000156 DAPOAV010000000
VERSION     DAPOAV010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6408
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.157"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..2717)
                     /locus_tag="RN951_004227"
     CDS             complement(<1..2717)
                     /locus_tag="RN951_004227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310126.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDX2529127.1"
                     /translation="MRNLCFLLTLVATLLLPGRLIAAALPQDEKLITGQLDNGLRYMI
                     YPHAHPKDQVNLWLQIHTGSLQEEDNERGVAHFVEHMMFNGTKTWPGNKVIETFESMG
                     LRFGRDVNAYTSYDETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEVDAERGVI
                     TEEWRAHQDAKWRTSQARRPFLLANTRNLDREPIGLMDTVATVTPAQLRQFYQRWYQP
                     NNMTFIVVGDIDSKEALALIKDNLSKLPANKAAENRVWPTKAENHLRFNIINDKENRV
                     NGIALYYRLPMVQVNDEQSFIEQAEWSMLVQLFNQRLQERIQSGELKTISGGTARSVK
                     IAPDYQSLFFRVNARDDNMQDAANALMAELATIDQHGFSAEELDDVKSTRLTWLKNAV
                     DQQAERDLRMLTSRLASSSLNNTPFLSPEETYQLSKRLWQQITVQSLAEKWQQLRKNQ
                     DAFWEQMVNNEVAAKKALSPAAILALEKEYANKKLAAYVFPGRNLSLTVDADPQAEIS
                     SKETLAENLTSLTLSNGARVILAKSAGEEQKLQIIAVSNKGDLSFPAQQKSLIALANK
                     AVSGSGVGELSSSSLKRWSAENSVTMSSKVSGMNTLLSVSARTNNLEPGFQLINQRIT
                     HSTINDNIWASLQNAQIQALKTLDQRPAEKFAQQMYETRYADDRTKLLQENQIAQFTA
                     ADALAADRQLFSSPADITFVIVGNVAEDKLVALITRYLGSIKHSDSPLAAGKPLTRAT
                     DNASVTVKEQNEPVAQVSQWKRYDSRTPVNLPTRMALDAFNVALAKDLRVNIREQASG
                     AYSVSSRLSVDPQAKDISHLLAFTCQPERHDELLTLANEVMVKRLAKGISEQELNEYQ
                     QNVQRSLDIQQRSVQQLANTIVNSLIQYDDPAAWTEQEQLLKQMTVENV"
     gene            complement(2774..5146)
                     /locus_tag="RN951_004228"
     CDS             complement(2774..5146)
                     /locus_tag="RN951_004228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor plug domain-containing
                     protein"
                     /protein_id="HDX2529128.1"
                     /translation="MKRVLIPGVILCGADVAQAVDDKNMYMHFFEEMTVYAPVPVPVN
                     GNTHYTSESIERLPTGNGNISDLLRTNPAVRMDSTQSTSLNQGDIRPEKISIHGASPY
                     QNAYLIDGISATNNLNPANESDASSATNISGMSQGYYLDVSLLDNVTLYDSFVPVEFG
                     RFNGGVIDAKIKRFNADDSKVKLGYRTTRSDWLTSHIDENNKSAFNQGSSGSTYYSPD
                     FKKNFYTLSFNQELADNFGVTAGLSRRQSDITRADYVSNDGIVAGRAQYKNVIDTALS
                     KFTWFASDRFTHDLTLKYTGSSRDYNTSTFPQSDREMGNKSYGLAWDMDTQLAWAKLR
                     TTVGWDHISDYTRHDHDIWYTELSCTYGDITGRCTRGGLGHISQAVDNYTFKTRLDWQ
                     KFAVGNVSHQPYFGAEYIYSDAWTERHNQSESYVINAAGKKTNHTIYHKGKGRLGIDN
                     YTLYMADRISWRNVSLMPGVRYDYDNYLSNHNISPRFMTEWDIFANQTSMITAGYNRY
                     YGGNILDMGLRDIRNSWTESVSGNKTLTRYQDLKTPYNDELAMGLQQKIGKNVIARAN
                     YVYREAHDQISKSSRTDSATKTTITEYNNDGKTKTHSFSLSFELAEPLHIRQVDINPQ
                     IVFSYIKSKGNLSLNNGYEESNTGDNQVVYNGNLVSYDSVPVADFNNPLKISLNMDFT
                     HQPSGLVWANTLAWQEARKARIILGKTNAQYISEYSDYKQYVDEKLDSSLTWDTRLSW
                     TPQFLQQQNLTISADILNVLDSKTAVDTTNTGVATYASGRTFWLDVSMKF"
     gene            complement(5184..>6408)
                     /locus_tag="RN951_004229"
     CDS             complement(5184..>6408)
                     /locus_tag="RN951_004229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HDX2529129.1"
                     /translation="SFGFIQSLSMLITFTVILWESAGTLSFTVGGTEWNIQGYMVYTV
                     VLIVIGGTLFTHKVGKRIRPLNVEKQRSEATFRTNLVQHNKQAELIALSNAESLQRQE
                     LSDNFHTIKENWHRLMNRQRWLDYWQNIYSRSLSVLPYFLLLPQFISGQINLGGLMKS
                     RQAFMLVSNNLSWFIYKYDELAELAAVIDRLYEFHQLTEQRPTNKPKNCQHAVQVADA
                     SIRTPDNKIILENLNFHVSPGKWLLLKGYSGAGKTTLLKTLSHCWPWFKGDISSPADS
                     WYVSQTPLIKTGLLKEIICKALPLPVDDKSLSEVLHQVGLGKLAARIHDHDRWGDILS
                     SGEKQRIALARLILRRPKWIFLDETTSHLEEQEAIRLLRLVREKLPTSGVIMVTHQPG
                     VWNLADDICDISAVL"
BASE COUNT         1623 a         1502 c         1452 g         1831 t
ORIGIN      
        1 ttaacattct ctaccgtcat ttgtttcaac aattgctcct gctcagtcca tgctgcagga
       61 tcgtcatatt gaataagact atttacaata gtgttcgcta attgttgaac gctacgctgt
      121 tggatatcga ggctgcgctg aacgttttgc tggtattcat tcagttcttg ctcactgatc
      181 cctttagcca gacgcttaac catcacttca ttcgctaacg ttaacagttc atcatgtcgt
      241 tctggttgac aagtaaaagc cagcaaatga ctgatatctt tggcctgagg atcaaccgag
      301 aggcgagaag aaacgctgta tgctccagat gcctgttcac gaatattaac acgtagatct
      361 tttgccagtg cgacgttaaa agcatcgagc gccatacgcg tcggcagatt aacaggtgtc
      421 cgggaatcat aacgcttcca ctgtgaaacc tgtgccacag gttcattttg ttcttttaca
      481 gtaaccgatg cgttgtccgt cgcgcgagtt aatggtttac ctgcggctaa tggcgaatca
      541 gagtgtttga ttgatcctaa gtaacgcgta attaacgcca cgagtttgtc ttctgcgaca
      601 ttaccgacaa tgacaaacgt gatatccgct ggagatgaaa acaattggcg atcggcagcc
      661 agcgcatctg cggcagtaaa ctgtgcaatc tgattttctt gcagtaattt cgtgcggtca
      721 tcagcatagc gcgtctcata catctgctgg gcgaatttct ccgctggacg ctggtcgagc
      781 gttttcaacg cctgaatttg agcattttgt agcgatgccc aaatattatc gttaatcgtg
      841 ctgtgggtga ttcgctggtt aatcaactga aaaccaggtt caaggttatt agtccgcgcg
      901 ctaacggaga gcaacgtatt catgccactg actttactgc tcatggttac cgaattttcc
      961 gcactccagc gtttcaggct ggaagaggag agttcgccaa cgccgcttcc gctaactgct
     1021 ttatttgcca gcgcgataag tgatttttgc tgcgcaggga aacttaaatc gcctttattc
     1081 gatacggcaa taatttgtag cttttgctct tcacccgcgg attttgccag aataaccctg
     1141 gcaccattgg aaagtgttaa tgatgtcaga ttctccgcca gcgtttcttt gctgctaatt
     1201 tccgcctgtg ggtctgcgtc tactgttaac gataaatttc tgcctgggaa gacgtaagcc
     1261 gccagctttt tgttggcgta ctccttttcc agcgccagga tagccgcagg agacaatgct
     1321 tttttggcgg caacctcatt gtttaccatt tgctcccaaa atgcgtcctg gttctttctt
     1381 aactgctgcc atttttccgc cagactttgc acggtaattt gctgccacag acgtttcgaa
     1441 agttgatatg tctcttccgg cgacaagaac ggcgtattat ttaatgagct ggatgccagg
     1501 cgactggtca gcatacgtaa atcacgttca gcttgctgat caaccgcatt tttcagccag
     1561 gtgaggcggg tagatttgac atcatcgagt tcttcagcag aaaaaccatg ctgatcaatg
     1621 gttgccaact ctgccattaa tgcattcgca gcatcctgca tattatcgtc tcgtgcattt
     1681 acacggaaaa acagcgactg ataatcgggt gcaattttaa cgctgcgcgc agtgccgcca
     1741 gaaatagtct tcaactcgcc cgactgtatg cgttcctgca gacgttgatt gaacagctga
     1801 actaacatgc tccattcagc ttgttcgata aagctttgct catcgttcac ttgtaccatt
     1861 ggcaggcgat aatagagtgc gatgccgttc acccggtttt ctttatcatt aatgatatta
     1921 aagcgcaggt ggttttcggc ttttgtcggc cagacgcgat tttcagctgc tttgttagcc
     1981 ggaagcttac ttaaattatc ctttatcagc gccagcgctt ctttactgtc gatatcgccg
     2041 accacgataa aggtcatatt atttggttga taccagcgtt gataaaattg gcgcaattgt
     2101 gccggtgtga ccgtggcgac agtatccatc aggccgatag gttcacggtc taaattacgg
     2161 gtatttgcca gcaggaaagg gcggcgcgcc tgagaggtgc gccatttcgc atcctgatgg
     2221 gcacgccatt cctcagtaat tacgccacgt tcagcgtcta cttcgagttt ttcaaaggtt
     2281 gcggcattac tccattcact gaagattgcc atcacttgtt gcagattttg tttctgcgta
     2341 gtcggcaaac tcacctgata caccgtttcg tcatagctgg tataggcatt aacatcgcga
     2401 ccaaaacgca ggcccattga ctcaaatgtt tcgatgactt tattacccgg ccatgttttt
     2461 gtgccgttaa acatcatatg ttctacaaaa tgagccacgc cgcgctcatt gtcttcttcc
     2521 tgcaatgaac cggtatgaat ttgcagccat aaatttacct gatcctttgg atgagcatgc
     2581 ggataaatca tatatcgcaa gccattgtcc agttgcccgg taattaactt ttcatcctgc
     2641 ggtaaggcgg cggcaatcag ccgcccgggg agcaacagag ttgccactaa cgtcagtaag
     2701 aaacagaggt ttctcataat tatctccatg cgaaaaccgg gcgaatttac ccggttaagt
     2761 aaaatccgaa ctattaaaat ttcatgctga catcaagcca gaaagtacgg ccactggcgt
     2821 aggtcgccac accggtgttc gttgtatcaa cagcggtttt gctatccagt acattgagaa
     2881 tatcggcact gatcgtcagg ttttgttgtt gcagaaattg tggcgtccag gacaagcggg
     2941 tgtcccaggt caggctgcta tccagttttt cgtcaacata ctgcttgtaa tctgaatatt
     3001 cgctgatgta ttgcgcattt gtcttaccaa ggataatgcg agctttacgc gcttcttgcc
     3061 aggccagcgt attcgcccac actaacccgc tcggttgatg cgtgaaatcc atgtttaagg
     3121 agatctttaa tgggttatta aaatctgcca ctggaacgct atcgtaagag accagattac
     3181 cgttataaac cacctggtta tcaccggtat tgctctcctc ataaccattg tttaacgaca
     3241 agttgccctt gctcttgata tagctaaaga caatttgtgg gttaatatct acctggcgga
     3301 tatgcagggg ttcggccagt tcaaaactga ggctgaacga atgcgttttg gttttgccat
     3361 cgttgttata ttcagtaatg gtggttttag tcgcgctgtc ggtacgactg cttttgctga
     3421 tttgatcatg cgcttcacgg taaacatagt ttgcacgcgc aataacgttc ttaccgattt
     3481 tctgctgcaa tcccattgcc agttcatcgt tataaggcgt tttcaaatcc tgataacgcg
     3541 tcagagtttt attacctgat accgattccg tccagctatt gcggatatca cgtaatccca
     3601 tatcaagaat attcccgcca tagtaacggt tataacctgc tgtaatcatt gaggtttgat
     3661 tagcaaaaat atcccattcc gtcataaagc gcggggagat attgtggttt gacagatagt
     3721 tgtcatagtc ataccgcacg ccgggcatta atgacacatt acgccagcta atgcgatccg
     3781 ccatatacag cgtgtagttg tcaattccca ggcggccttt acctttatgg taaatggtat
     3841 ggttagtttt ctttccggca gcattaatca cataggattc agactggtta tggcgttcag
     3901 tccacgcatc ggaatagatg tattccgcgc cgaagtaggg ttgatgcgaa acattaccca
     3961 cggcgaattt ttgccagtcc aggcgtgttt tgaaggtgta attatctaca gcctgggaaa
     4021 tgtgtcctaa tccgccacgg gtgcaacgcc ctgtaatatc accatatgta catgaaagtt
     4081 cggtgtacca gatgtcatga tcgtgacggg tataatcact aatatgatcc caaccaacgg
     4141 tggtacgcag tttggcccat gcgagctgcg tatccatatc ccatgccaga ccataggatt
     4201 tattacccat ttcgcgatca gactgcggga aggtgctggt attataatca cggctggagc
     4261 cggtatattt taaggttaaa tcgtgggtaa agcggtcgct ggcaaaccag gtaaatttgc
     4321 ttaatgcagt atcgataacg tttttatact gtgcccgacc ggcgacaatg ccgtcattcg
     4381 aaacataatc cgcgcgggtg atatcagact ggcggcgcga taaaccggcg gtaacgccga
     4441 agttatcagc gagttcctga ttaaacgaca aggtataaaa gttcttttta aaatctgggg
     4501 agtaataagt acttcctgaa gagccttgat taaatgcgct cttgttattc tcatcgatat
     4561 gcgatgttaa ccagtccgaa cgcgtagtgc gataacccaa tttcaccttg ctatcatcag
     4621 cgttgaagcg tttgatcttt gcatcaatta ccccgccatt gaagcgacca aattcaaccg
     4681 gcacaaaact gtcataaagc gtcacattgt ccagtaagct gacatcaaga taatacccct
     4741 gtgacatccc gctaatattg gttgcactac tggcatcgga ctcattcgct gggttcaggt
     4801 tattagttgc actaataccg tcaatcaaat aggcattctg gtagggcgac gcaccgtgaa
     4861 tagagatttt ctcagggcga atatctccct ggttcaacga ggtactttgc gttgaatcca
     4921 tgcgtaccgc agggttggtt ctcagcagat cgctgatatt gccattcccg gtcggtaaac
     4981 gctcgatgct ttcactggtg taatgcgtgt tgccgtttac gggtacaggg acaggagcat
     5041 agaccgtcat ctcttcaaaa aaatgcatgt acatgttttt gtcatcgacg gcctgcgcca
     5101 catcagcgcc acataaaatg acgccaggaa taagaactcg cttcatttat ttatatctcc
     5161 gtacagcagg gcttttattg tttttataaa accgcgctaa tgtcacaaat atcatcggcc
     5221 aggttccaga caccgggttg atgtgtaacc ataatgacgc cgcttgtggg tagtttttca
     5281 cgcactaaac gcagtaagcg gatagcctct tgttcctcaa gatgagaggt agtttcgtca
     5341 agaaatatcc atttcggacg tcgtaaaatt aatcgtgcca gggcgatacg ttgtttttcg
     5401 ccgctggaaa gaatatctcc ccagcgatcg tggtcatgaa tacgcgcagc caatttccca
     5461 agaccaacct gatgcagtac ttcgctcaac gatttatcgt ctacgggcag gggaagtgct
     5521 ttacaaataa tctctttcag taagccggtt ttgattaacg gtgtttgtga cacataccaa
     5581 ctgtcagcag gagaagaaat atcaccttta aaccacggcc agcagtggga taatgtttta
     5641 agcagtgtgg tttttcccgc gccagagtag cctttcagta atagccattt gcctggcgaa
     5701 acatgaaagt tcaggttctc taatatgatc ttattatcag gcgtacgaat actcgcatca
     5761 gccacttgta ccgcatgttg gcaattttta ggcttattcg tagggcgctg ttcagtgagt
     5821 tgatggaact catacaagcg atcgataacc gcagccagtt cagcaagttc gtcatattta
     5881 taaataaacc agcttaaatt gttcgatacc agcataaatg cctggcgcga tttcatcagt
     5941 ccgcccagat tgatctgccc gctaataaac tgcggcaata acagaaagta gggaagaacg
     6001 ctaagcgagc gcgaataaat attctgccag taatcaagcc accgctgacg attcattaaa
     6061 cgatgccagt tctctttaat ggtatgaaaa ttgtcgctca actcctggcg ttgtagagac
     6121 tcagcattgc ttagcgcaat cagttctgcc tgcttattat gctgcacaag atttgttcga
     6181 aatgtcgctt cgctacgttg tttttccaca ttaagcggac gaatacgttt acccacctta
     6241 tgggtaaata aagttccacc gatcacaatg agcacgacgg tatagaccat atacccctgg
     6301 atattccatt ctgttccacc aacagtgaat gagagcgtac ccgcgctttc ccaaagaata
     6361 acggtaaagg tgatcagcat gctaagtgac tggatgaagc caaatgaa
//
LOCUS       DAPOAV010000157         6275 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.158, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000157 DAPOAV010000000
VERSION     DAPOAV010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6275
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.158"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            57..986
                     /gene="pfkB"
                     /locus_tag="RN951_004230"
     CDS             57..986
                     /gene="pfkB"
                     /locus_tag="RN951_004230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416237.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase II"
                     /protein_id="HDX2529130.1"
                     /translation="MVRIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINV
                     ARAIAHLGGSATAIFPAGGATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGE
                     QYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQG
                     IRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKA
                     KRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMV
                     RFGVAAGSAATLNQGTRLCSHDDTQKIYAYLSR"
     gene            1087..1377
                     /gene="ghoS"
                     /locus_tag="RN951_004231"
     CDS             1087..1377
                     /gene="ghoS"
                     /locus_tag="RN951_004231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system endoribonuclease
                     antitoxin GhoS"
                     /protein_id="HDX2529131.1"
                     /translation="MASGDLVRYVITVMLHEDTLTEINELNNYLTRDGFLLTMTDDEG
                     NIHELGTNTFGLISTQSEEEIRELVSGLTQSATGKDPEITITTWEEWNSNRK"
     gene            1483..2343
                     /locus_tag="RN951_004232"
     CDS             1483..2343
                     /locus_tag="RN951_004232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HDX2529132.1"
                     /translation="MWQAISRLLSEQLGEGEIELRNELPGGEVHAAWHLRYAGHDFFV
                     KCDERELLPGFTAEADQLELLSRSKTVTVPKVWAVGADRDYSFLVMDYLPPRPLDAHS
                     AFILGQQIARLHQWSDQPQFGLDFDNALSTTPQPNTWQRRWSTFFAEQRIGWQLELAA
                     EKGIAFGNIDAIVEHIQQRLASHQPQPSLLHGDLWSGNCALGPDGPYIFDPACYWGDR
                     ECDLAMLPLHTEQPPQIYDGYQSVSPLPADFLERQPVYQLYTLLNRARLFGGQHLVIA
                     QQSLDRLLAA"
     gene            complement(2384..2920)
                     /locus_tag="RN951_004233"
     CDS             complement(2384..2920)
                     /locus_tag="RN951_004233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YniB family protein"
                     /protein_id="HDX2529133.1"
                     /translation="MTYQQAGRIAVLKRILGWVIFIPALISTLISLLKFMNTRQENKE
                     GINAVMLDFTHVMIDMMQANTPFLNLFWYNSPTPNFNGGVNVMFWVIFILIFVGLALQ
                     DSGARMSRQARFLREGVEDQLILEKAKGEEGLTREQIESRIVVPHHTIFLQFFSLYIL
                     PVICIAAGYVFFSLLGFI"
     gene            3067..3735
                     /gene="hxpB"
                     /locus_tag="RN951_004234"
     CDS             3067..3735
                     /gene="hxpB"
                     /locus_tag="RN951_004234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexitol phosphatase HxpB"
                     /protein_id="HDX2529134.1"
                     /translation="MSTPRQILAAIFDMDGLLIDSEPLWDRAELDVMASLGVDISRRN
                     ELPDTLGLRIDMVVDLWYARQPWNGPSRQEVVERVIARAISLVEETRPLLPGVREAVA
                     LCKEQGLLVGLASASPLHMLEKVLTMFDLRDSFDALASAEKLPYSKPHPQVYLDCAAK
                     LGVDPLTCVALEDSVNGMIASKAARMRSIVVPAPEAQNDPRFVLADVKLSSLTELTAK
                     DLLG"
     gene            3898..4488
                     /locus_tag="RN951_004235"
     CDS             3898..4488
                     /locus_tag="RN951_004235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707386.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDX2529135.1"
                     /translation="MTAEGHLLFSIACAVFAKNAELTPVLAQGDWWHIVPSAILTCLL
                     PDIDHPKSFLGQRLKWISKPIARAFGHRGFTHSLLAVFALLATFYLKVPEGWFIPADA
                     LQGMVLGYLSHILADMLTPAGVPLLWPCRWRFRLPILVPQKGNQLERFICMALFVWSV
                     WMPHSLPENSAVRWSSQMINTLQIQFHRLIKHQVEY"
     gene            4621..6012
                     /gene="tcyP"
                     /locus_tag="RN951_004236"
     CDS             4621..6012
                     /gene="tcyP"
                     /locus_tag="RN951_004236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine/sulfocysteine:cation symporter"
                     /protein_id="HDX2529136.1"
                     /translation="MNFPLIANIVVFVVLLFALAQTRHKQWSLAKKVLVGLVMGVVFG
                     LALHTIYGSDSQVLKDSVQWFNIVGNGYVQLLQMIVMPLVFASILSAVARLHNASQLG
                     KISFLTIGTLLFTTLIAALVGVLVTNLFGLTAEGLVQGGAETARLNAIESNYVGKVSD
                     LSVPQLVLSFIPKNPFADLTGANPTSIISVVIFAAFLGVAALKLLKDDAPKGERVLAA
                     IDTLQSWVMKLVRLVMQLTPYGVLALMTKVVAGSNLQDIIKLGSFVVASYLGLLIMFA
                     VHGILLGINGVSPLKYFRKVWPVLTFAFTSRSSAASIPLNVEAQTRRLGVPESIASFA
                     ASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPMWIATLVGIVTVSSAGVAGVGGG
                     ATFAALIVLPAMGLPVTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKA
                     ILDSEDDAELAHH"
     gene            complement(6016..>6275)
                     /locus_tag="RN951_004237"
     CDS             complement(6016..>6275)
                     /locus_tag="RN951_004237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416244.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529137.1"
                     /translation="LNLPGMGSGVLEDIMSIPDSSLRKRLGYEVLSFSLQAHSLSQEC
                     IDKLDVFFADDLFKYESVCIAAMEHLKSKATAPIQNGPLPA"
BASE COUNT         1533 a         1552 c         1575 g         1615 t
ORIGIN      
        1 ttcttcactt tccgctgatt cggtgccaga ctgaaatcag cctataggag gaaatgatgg
       61 tacgtatcta tacgttgaca cttgcgccct ctctcgatag cgcaacaatt accccgcaaa
      121 tttatcccga aggaaaactg cgctgtaccg caccggtgtt cgaacccggg ggcggcggca
      181 tcaacgtcgc ccgcgccatt gcccatcttg gaggcagtgc cacagcgatc ttcccggcgg
      241 gtggcgcgac cggcgaacac ctggtttcac tgttggcgga tgaaaatgtc cccgtcgcta
      301 ctgtagaagc caaagactgg acccggcaga atttacacgt acatgtggaa gcaagcggtg
      361 agcagtatcg ttttgttatg ccaggcgcgg cattaaatga agatgagttt cgccagcttg
      421 aagagcaagt tctggaaatt gaatccgggg ccatcctggt cataagcgga agcctgccgc
      481 caggtgtgaa gctggaaaaa ttaacccaac tgatttccgc tgcgcaaaaa caagggatcc
      541 gctgcatcgt cgacagttct ggcgaagcgt taagtgcagc actggcaatt ggtaacatcg
      601 agttggttaa gcctaaccaa aaagaactca gtgcgctggt gaatcgcgaa ctcacccagc
      661 cggacgatgt ccgcaaagcc gcgcaggaaa tcgttaatag cggcaaggcc aaacgggttg
      721 tcgtttccct gggtccacaa ggagcgctgg gtgttgatag tgaaaactgt attcaggtgg
      781 tgccaccacc ggtgaaaagc cagagtaccg ttggcgctgg tgacagcatg gtcggcgcga
      841 tgacactgaa actggcagaa aatgcctctc ttgaagagat ggttcgtttt ggcgtagctg
      901 cggggagtgc agccacactc aatcagggaa cacgtctgtg ctcccatgac gatacgcaaa
      961 aaatttacgc ttacctttcc cgctaacaaa aacattcccc cagcattggg ggaatcatca
     1021 ccaacctgtc ggcaacgcgt ttctccgact atgctcaaaa gtcatgtgat aacaaagggg
     1081 tgaactatgg ccagtggcga tcttgtccgt tatgtcataa ccgtcatgtt gcatgaggat
     1141 acattgactg aaattaacga gttgaataat tacctgactc gcgacggttt tttgctcact
     1201 atgacggatg atgagggaaa tatccatgag ctgggaacta acacttttgg acttatcagt
     1261 acccaaagtg aagaagaaat tagagaactg gtttcggggc ttacccaaag tgcaaccggc
     1321 aaagatcctg aaatcaccat cacgacctgg gaggaatgga atagcaacag aaaataaatg
     1381 gtttttgggc aataatcagt ctgtggtgtg cgttagctcg tgtttttaca ccgcattctt
     1441 gcgctaacct tatgatctgg cagacaacat gggagagaca tcatgtggca ggcaatcagt
     1501 cgtcttttga gcgagcagtt aggtgaaggc gaaatcgaac tgcgtaatga actgcctggc
     1561 ggagaagtcc atgccgcatg gcatttgcgc tatgcaggac atgatttttt cgtcaaatgt
     1621 gatgaaaggg aactgcttcc cggttttacc gccgaagccg accaactgga gttactgtcg
     1681 cgtagtaaaa ccgtcaccgt gcctaaggtt tgggcagttg gcgctgaccg tgactacagt
     1741 tttctggtga tggattatct cccacctcgt ccgctggatg cgcatagcgc atttattctt
     1801 ggtcagcaaa ttgcgcgttt acatcaatgg agcgaccaac cacaatttgg ccttgatttc
     1861 gataacgcgc tctccacaac tccacagccc aacacctggc aacgtcgctg gtcaacgttt
     1921 tttgctgaac aacggattgg ctggcagttg gaactggctg cagaaaaagg gatcgctttc
     1981 ggcaatatcg acgccatcgt cgagcatatt cagcagcgtc tggcctcaca tcaaccgcag
     2041 ccttctctgt tgcacggcga tttatggtcc ggcaactgtg cactgggtcc ggatggcccg
     2101 tacattttcg acccggcctg ctactggggt gaccgagagt gcgacctggc gatgttaccg
     2161 ctgcatactg aacagccgcc acaaatctat gacggctatc agtcagtatc cccgctacct
     2221 gccgatttcc ttgaacgtca accggtttac caactctaca cgctgttaaa tcgtgcaagg
     2281 ttatttggcg gtcagcattt ggttattgct cagcagtcat tggatagatt attagcagca
     2341 tgatatgggt tgaggataat ggccgctccg tgcggccttt tgattaaata aacccaagca
     2401 gagaaaagaa cacataacct gcagcaatac aaataaccgg caggatatac agtgagaaaa
     2461 actgcaggaa aatagtatgg tgcggaacaa caatacggga ctcaatttgt tcacgcgtta
     2521 gcccctcttc ccctttggct ttttccagaa tgagttgatc ttcaacacct tcccgcaaga
     2581 agcgcgcctg gcgactcatc cgggcaccgg aatcctgcaa cgccagtccg acaaaaatca
     2641 ggatgaaaat cacccagaac ataacgttca cgccaccatt aaaattgggc gtcggggagt
     2701 tataccagaa tagattcaaa aaaggcgtat tcgcctgcat catatcgatc atgacatgag
     2761 taaagtcgag catgaccgca ttaatgcctt ccttgttttc ctgccgggta ttcataaatt
     2821 tcagcaaaga aatcaatgta gagatcaatg caggtataaa aatcacccaa cccaaaatcc
     2881 ttttcaaaac agcaatgcgt ccagcttgtt gatacgtcat gagttctcct tgattaagac
     2941 gcgtcgtttc acttagttta cctgtagata tctgttttcg cccattcttt aaaggcgata
     3001 tgataggcgc ttaatcataa gcacggctta ataccttaca cataatgctc taaaggagag
     3061 gttgtaatgt caaccccgcg tcagattctt gctgcaattt ttgatatgga tggattactt
     3121 atcgactcag aacctttatg ggatcgagcc gaactggatg tgatggcaag cctgggggtg
     3181 gatatctccc gtcgtaacga gctgccggac accttaggtt tacgcatcga tatggtggtc
     3241 gatctttggt acgcccggca accgtggaat gggccaagcc gtcaggaagt agtagaacgg
     3301 gttattgccc gtgccatttc actggttgaa gagacacgtc cattattacc aggcgtgcgc
     3361 gaagccgttg cgttatgcaa agaacaaggt ttattggtgg gactggcctc cgcgtcacca
     3421 ctacatatgc tggaaaaagt gttgaccatg tttgacttac gcgacagttt cgatgccctc
     3481 gcctcggccg aaaaactgcc ttacagcaag ccgcatccgc aagtatatct cgactgcgca
     3541 gcaaaactgg gcgttgaccc tctgacctgc gtagcgctgg aagattcggt aaatggcatg
     3601 atcgcctcta aagcagcccg catgcgctcc atcgtcgttc ctgcgccaga agcgcaaaat
     3661 gatccacgtt ttgtattagc agacgtcaaa ctctcatcgc tgacagaact caccgcaaaa
     3721 gaccttctcg gttaatgacc aggggcagtg atctcgctgc ccctggttct ttatctgaaa
     3781 ttgcattcaa ctgacggatt aatcgtcaat ttaagagaaa gagttacacc gtcaccactt
     3841 ccgtgcactg tataaaaatc ctatactgta cgtatcgaca gtttagtgag ttttatcatg
     3901 acggcggaag gtcaccttct cttttctatt gcttgtgcgg tatttgccaa aaatgccgag
     3961 ctgacgcccg tgctggcaca gggtgactgg tggcatattg tcccttccgc aatcctgacg
     4021 tgtttgttac cggacatcga tcacccaaag tcgtttcttg ggcagcgatt aaaatggata
     4081 tcaaaaccga tcgcccgcgc ttttgggcat cgtggtttta cccacagtct gctggcggta
     4141 tttgcgctgc tggcaacctt ttaccttaag gttccggaag gctggttcat tccggctgat
     4201 gcgctacaag gaatggtgct gggttatttg agccacatac ttgccgatat gctgacaccc
     4261 gccggtgttc ccctgctctg gccatgccgc tggcgtttcc gcttgcctat cctggttccc
     4321 caaaagggca accaactgga acgttttatc tgcatggcat tatttgtctg gtcggtatgg
     4381 atgccccatt cattacccga gaacagcgct gttcgttggt catcgcaaat gatcaatacc
     4441 ttgcagatcc agtttcatcg gcttattaag catcaggttg aatactaaaa aggcaaaaat
     4501 cacctttctg gaataagcaa ttccatttga atataagagc cagctcacag ttctgttaat
     4561 cttgcgccaa cactatgact gctacgcagt gatagaaata ataagatcag gagaacgggg
     4621 atgaactttc cattaattgc gaacatcgtg gtgttcgttg tactgctgtt tgcgctggct
     4681 cagacccgcc ataaacagtg gagtctggcg aaaaaagtgc tggtgggtct ggtgatgggt
     4741 gtggtttttg gccttgccct gcataccatt tatggttctg acagccaggt acttaaagat
     4801 tctgtacagt ggtttaacat cgttggtaac ggctatgttc aactgctgca aatgatcgtt
     4861 atgccgttag tcttcgcctc tattctgagc gcggttgccc gtctgcataa cgcatctcag
     4921 ttaggcaaaa tcagttttct gaccatcggt acgcttttgt ttaccacgct gattgcggcg
     4981 ctggtcggtg tgctggtcac caacctgttt ggtttgacgg ctgaaggtct ggttcagggt
     5041 ggtgcagaaa ctgcacgtct gaacgccatt gaaagtaact atgttggtaa agtctctgat
     5101 ctgagcgttc cgcagctggt cttgtccttt atcccgaaaa acccgtttgc cgatcttacc
     5161 ggagccaatc cgacgtcaat tatcagcgtg gtaatttttg ccgcattcct cggcgtagct
     5221 gcattgaaac tgctgaagga tgatgcgccg aaaggtgaac gcgtcttagc cgctatcgat
     5281 accctacaaa gctgggtgat gaaactggtt cgcctggtca tgcagttgac cccttacggc
     5341 gttctggctc taatgaccaa agtggttgca ggttctaact tgcaagacat catcaaactg
     5401 ggaagtttcg ttgtcgcgtc ctacctcggt ctgctgatta tgtttgcagt gcatggcatt
     5461 ctgctgggca ttaatggcgt gagtccgctg aagtacttcc gtaaggtatg gcctgtgctg
     5521 acgtttgcct ttaccagccg ttccagtgct gcgtctatcc cactgaatgt ggaagcacaa
     5581 acgcgtcgtc tgggcgttcc tgaatccatc gccagtttcg ccgcctcttt cggtgcaacc
     5641 attggtcaga acggctgcgc cggtttgtat ccggcaatgc tggcggtgat ggttgcgcct
     5701 acggttggca ttaacccgct ggacccgatg tggattgcga cgctggtcgg tattgttacc
     5761 gttagttccg caggcgttgc cggtgtcggt ggtggtgcaa ctttcgccgc actgattgta
     5821 ctgcctgcga tgggcctgcc agtaaccctg gtggcgctgt taatctccgt tgaaccgctt
     5881 atcgacatgg gccgtacggc gttaaacgtt agtggctcga tgacagctgg cacgctgacc
     5941 agccagtggc tgaagcaaac cgataaagcc attctggata gcgaagacga cgccgaactg
     6001 gcacaccatt aattcttatg ctggcaacgg tccgttttgt ataggggccg ttgccttact
     6061 ttttaaatgt tccatcgcgg cgatgcatac tgactcatat ttaaacagat cgtcagcgaa
     6121 aaaaacgtcc aacttatcaa tacattcctg gctcaatgaa tgtgcctgta gcgagaagct
     6181 taaaacctca tacccgagac gttttctaag tgaactatct ggaatactca taatatcttc
     6241 aagcacacca cttcccattc ccggaagatt tagtg
//
LOCUS       DAPOAV010000158         6148 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.159, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000158 DAPOAV010000000
VERSION     DAPOAV010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6148
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.159"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..1436
                     /locus_tag="RN951_004238"
     CDS             <1..1436
                     /locus_tag="RN951_004238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HDX2529138.1"
                     /translation="ATLPVYDRNNLAPRIVHLGFGAFHRAHQGVYADILATEHFSDWG
                     YYEVNLIGGEQQIADLQQQDNLYTVAEMSADVWTARVVGVVKKALHVQIDGLETVLAA
                     MCEPQIAIVSLTITEKGYFHSPATGQLMLDHPMVAADVQNPHQPKTATGVIVEALARR
                     KAAGLPAFTVMSCDNMPENGHVMRDVVTSYAQAVDVKLAQWIEDNVTFPSTMVDRIVP
                     AVTEDTLAKIEQLTGVRDPAGVACEPFRQWVIEDNFVAGRPEWEKAGAELVSDVLPYE
                     EMKLRMLNGSHSFLAYLGYLAGYQHINDCMEDEHYRYAAYGLMLQEQAPTLKVQGVDL
                     QDYANRLIARYSNPALRHRTWQIAMDGSQKLPQRMLDSVRWHLAHDSKFDLLALGVAG
                     WMRYVGGVDEQGNPIEISDPLLPVIQKAVQSSAEGKARVQSLLAIKAIFGDDLPDNSL
                     FTARVTETYLSLLAHGAKATVAKYSVK"
     gene            complement(1471..1674)
                     /gene="ydfZ"
                     /locus_tag="RN951_004239"
     CDS             complement(1471..1674)
                     /gene="ydfZ"
                     /locus_tag="RN951_004239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium delivery protein YdfZ"
                     /protein_id="HDX2529139.1"
                     /translation="MTTYDRNRNAITTGSRVMVSGTGHTGKILSIDTEGLTAEQIRRG
                     KTVVVEGCEEKLAPLDLIRLGMN"
     gene            complement(1851..2537)
                     /gene="ydfH"
                     /locus_tag="RN951_004240"
     CDS             complement(1851..2537)
                     /gene="ydfH"
                     /locus_tag="RN951_004240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YdfH"
                     /protein_id="HDX2529140.1"
                     /translation="MTVETQLNPTQPVNQQIYRILRRDIVHCLIAPGTPLSEKEVSVR
                     FNVSRQPVREAFIKLAENGLIQIRPQRGSYVNKISMAQVRNGSFIRQAIECAVARRAA
                     SMITESQCYQLEQNLHQQRIAIERKQLDDFFELDDNFHQLLTQIADCQLAWDTIENLK
                     ATVDRVRYMSFDHVSPPEMLLRQHLDIFSALQKRDGDAVERAMTQHLQEISESVRQIR
                     QENSDWFSEE"
     gene            complement(2626..3372)
                     /gene="ydfG"
                     /locus_tag="RN951_004241"
     CDS             complement(2626..3372)
                     /gene="ydfG"
                     /locus_tag="RN951_004241"
                     /EC_number="1.1.1.298"
                     /EC_number="1.1.1.381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional NADP-dependent 3-hydroxy acid
                     dehydrogenase/3-hydroxypropionate dehydrogenase YdfG"
                     /protein_id="HDX2529141.1"
                     /translation="MIVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDEL
                     GDNLYIAQLDVRNRAAIEEMLASLPAEWCNIDILVNNAGLALGMEPAHKASVEDWETM
                     IDTNNKGLVYMTRAVLPGMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLN
                     LRTDLHGTAVRVTDIEPGLVGGTEFSNVRFKGDDGKAEKTYQNTVALTPEDVSEAVWW
                     VSTLPAHVNINTLEMMPVTQSYAGLNVHRQ"
     gene            3509..5554
                     /gene="dcp"
                     /locus_tag="RN951_004242"
     CDS             3509..5554
                     /gene="dcp"
                     /locus_tag="RN951_004242"
                     /EC_number="3.4.15.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-dipeptidase Dcp"
                     /protein_id="HDX2529142.1"
                     /translation="MTTMNPFLVQSTLPYLAPHFDQIANHHYRPAFDEGMQQKRAEIA
                     AIALNPQMPDFNNTILALEQSGELLTRVTSVFFAMTAAHTNDELQRLDEQFSAELAEL
                     ANDIYLNGELFARVDAVWQRRESLGLDSESIRLVEVIHQRFVLAGAKLAQADKAKLKV
                     LNTEAATLTSQFNQRLLAANKSGGLVVNDIAQLAGMSEQEIALAAEAAREKGLDNKWL
                     IPLLNTTQQPALAEMRDRATREKLFIAGWTRAEKNDANDTRAIIQRLVEIRAQQATLL
                     GFPHYAAWKIADQMAKTPEAALNFMREIVPAARQRASDELASIQAVIDKQQGGFSAQP
                     WDWAFYAEQVRREKFDLDEAQLKPYFELNTVLNEGVFWTANQLFGIKFVERFDIPVYH
                     PDVRVWEIFDHNGVGLALFYGDFFARDSKSGGAWMGNFVEQSTLNKTHPVIYNVCNYQ
                     KPAAGEPALLLWDDVITLFHEFGHTLHGLFARQRYATLSGTNTPRDFVEFPSQINEHW
                     ATHPQVFARYARHYQSGAAMPDELQQKMRNASLFNKGYEMSELLSAALLDMRWHCLEE
                     NEAMQDVDDFELRALVAENMDLPAIPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADD
                     GYQWFVEQGGLTRENGLRFREAILSRGNSEDLERLYRQWRGKAPKIMPMLQHRGLNI"
     gene            complement(5598..6116)
                     /locus_tag="RN951_004243"
     CDS             complement(5598..6116)
                     /locus_tag="RN951_004243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo-tetronate isomerase"
                     /protein_id="HDX2529143.1"
                     /translation="MNINRDKIVQLVDTDTIENLTSALSQRLIADQLRLTTAESCTGG
                     KLASALCAAEDTPKFYGAGFVTFTDQAKMKILSVSQQSLERYSAVSEKVAAEMATGAI
                     ERADADVSIAITGYGGPEGGEDGTPAGTVWFAWHIKGQNYTAVMHFAGDCETVLALAV
                     RFALAQLLQLLL"
BASE COUNT         1529 a         1476 c         1581 g         1562 t
ORIGIN      
        1 aagcgacact ccctgtttat gatcgtaata acctggctcc aagaattgtt catttaggct
       61 ttggtgcatt tcaccgtgcg catcagggtg tgtatgccga tattcttgct acggaacatt
      121 tcagtgactg gggatattat gaggtcaact taatcggcgg cgaacagcaa attgccgatt
      181 tacaacagca agataatctt tataccgttg cggaaatgtc ggccgatgtg tggacggctc
      241 gcgtcgttgg cgtcgttaaa aaagccttgc acgtacagat agatggctta gaaaccgtgt
      301 tggcagcgat gtgtgaaccg caaatcgcga ttgtctctct gacaatcacc gaaaaagggt
      361 atttccactc tccggcgacc ggacagttaa tgctcgatca cccgatggta gctgccgacg
      421 tgcaaaatcc ccaccagccg aaaacagcaa caggggtgat tgttgaggcg ctggctcgcc
      481 gtaaagcggc aggacttccc gcatttaccg tcatgtcatg tgacaacatg ccagaaaacg
      541 gtcatgttat gcgtgacgtt gtcacttcct acgcacaagc cgttgatgta aaactggcac
      601 aatggatcga agataacgtg actttcccat caacaatggt ggaccgtatt gtgcccgcag
      661 tgacagagga tacgctggcg aaaatcgaac aacttaccgg tgtgcgcgat cctgcgggcg
      721 ttgcctgtga acctttccgc cagtgggtaa tagaagataa ctttgttgcc ggacgtccgg
      781 aatgggaaaa agcgggagcc gaactggtta gcgatgtgct gccttatgaa gagatgaagt
      841 tgcgcatgct caacggcagt cattcattcc tggcgtatct ggggtatctt gcaggatatc
      901 agcacattaa tgactgtatg gaagatgaac attatcgtta tgcggcgtat ggcttgatgt
      961 tgcaggaaca agcgccgacg ttgaaagtgc agggcgttga tttgcaagat tacgctaacc
     1021 gattaattgc acgctatagc aacccggcgt tacgtcatcg aacctggcag attgcgatgg
     1081 atggtagcca gaaattgcca cagcggatgt tggattctgt tcgctggcat ctggcgcatg
     1141 acagcaagtt cgatctgctg gcgctgggcg tcgcgggttg gatgcgttat gtcggtggtg
     1201 ttgatgaaca gggaaatccg atagaaatca gtgacccact gttacctgtt attcagaagg
     1261 ctgtacaaag tagtgccgaa gggaaagcgc gcgtccagtc attgctggcg attaaggcga
     1321 tctttggtga tgatttgcca gacaatagtt tgtttactgc aagagtgacg gaaacgtact
     1381 tgtctttatt agcgcatggc gcgaaagcga ccgtggcaaa atattccgtg aagtaaaaaa
     1441 gcaatgccgc catcggcggc attcacacgc ttagttcatg ccgagacgaa tcaggtccag
     1501 tggtgccagt ttctcttcac aaccttcaac aactacggtt tttccgcggc ggatttgctc
     1561 agcggtcaga ccttcagtat caatcgacag gatcttgcca gtgtgaccgg tgccgctaac
     1621 cataacacgg ctgccagtgg tgattgcgtt acggttacga tcgtaggtcg tcataggtgt
     1681 tttctccttt ctgatttaca gtcgaagccc acgtaacggg cgcaatataa atactcctgt
     1741 cgagtgaaat attttttgtt tttgatcaag ctcacatctt ttttgatgca tgcatgagcc
     1801 ataaggcggg ggaaaagact ctcaccccgg atgggatgag aggaaatgaa ttactcttcg
     1861 ctaaaccagt cgctgttttc ctggcggatc tggcgcacgg attcgctgat ttcctgcaaa
     1921 tgttgcgtca ttgcacgttc taccgcatcg ccatcacgtt tttgcagggc agagaaaata
     1981 tcaagatgct ggcgtaacag catttctggt ggagaaacgt ggtcgaaact catatagcgc
     2041 acgcgatcaa cggtcgcttt caggttctca atggtatccc acgccagttg acagtcggca
     2101 atctgcgtca ggagttgatg gaagttgtca tcaagttcaa aaaaatcatc cagttgcttg
     2161 cgctcaatgg caatgcgttg ctggtgaaga ttttgttcca gttgatagca ctggctttcg
     2221 gtaatcatgc tcgccgcccg acgcgccacc gcgcactcaa tggcctgacg gataaaactg
     2281 ccgttgcgca cctgggccat ggaaattttg ttgacgtagc tgccacgttg cggacgaatt
     2341 tgaatcaggc cgttttccgc cagtttaata aaggcttcac gaaccggctg gcgtgacaca
     2401 ttgaaacgaa cagaaacttc tttttccgac aacggtgtgc ctggagcaat caggcaatgg
     2461 acaatgtcgc gacgaagaat acgataaatc tgctgattga caggctgtgt gggattaagt
     2521 tgcgtttcga cggtcattcg ttcttgcttg tgagtgagtt aactgcatga gtctaccact
     2581 tttttgtgac aagcaataac ccggcagtta cgccgggtat aaaaattact gacggtggac
     2641 attcagtccg gcatagcttt gggtaaccgg catcatttcc agggtattga tattgacgtg
     2701 agcaggcagc gttgacaccc accagacggc ttcgctgaca tcttctggcg tcaatgcaac
     2761 ggtattttga taggtttttt ctgctttacc gtcatcgcct ttaaagcgga cattggaaaa
     2821 ctcggtacca cccaccagac ccggttcgat gtcggtgacg cgcaccgccg taccatgcag
     2881 atccgtacgc agattcaggc taaactgacg aacaaacgct ttcgtcgcac cgtaaacgtt
     2941 accaccggca tacggccagc tacctgccgt tgagccaatg ttaataatat gaccatgatt
     3001 acgttcaacc atacccggta agacggcgcg cgtcatatat accaggcctt tgttgttggt
     3061 atcaatcatc gtttcccagt cttcaacgct ggctttatgc gcaggctcca tgcccaacgc
     3121 caggccggca ttatttacca ggatatcaat attgcaccac tcggcaggaa gcgatgccag
     3181 catctcttca atagcggcgc ggttgcgaac gtccagttgg gcgatataca gattatctcc
     3241 cagttcgtct tttaactcct gcaaccgttc ctggcgacgg ccagtggcga taactttatg
     3301 cccttgttga ataaaacgac gagtaatgca ttcaccaaaa cctgccgttg ctccagttac
     3361 taaaacgatc atctcactgt tcctcaacgc ttttgtgtgt caataacata gcacgggatg
     3421 cttaagagcg ggtaatactg gattgcaaga ttgcactccg ttatcagtaa gcctacgcta
     3481 tggaacacct cgcgttcagg agaagaaaat gacaacaatg aatcctttcc ttgtgcaaag
     3541 cacactgccg tatctggctc cccattttga tcaaattgcc aatcatcact atcgcccggc
     3601 attcgatgag ggaatgcagc aaaagcgggc agaaattgct gccatcgcgc ttaacccgca
     3661 aatgcctgat ttcaacaata ctattctggc actggaacaa agcggagaat tacttacccg
     3721 cgttaccagc gtcttttttg cgatgactgc ggcgcatacc aatgatgaat tacagcgtct
     3781 tgacgagcag ttttccgctg aactggcgga actggctaat gatatctatc tgaacggtga
     3841 attattcgcg cgggtagatg ctgtctggca gcgccgtgaa tccctggggc ttgatagtga
     3901 atccatccgc ctggtggagg tgattcatca acgttttgtc cttgccggag ccaaacttgc
     3961 gcaagctgat aaagcaaaat taaaagtact gaatacagaa gctgcgaccc tgaccagcca
     4021 gtttaaccag cgattactgg cagcaaataa atccggcggt ctggttgtga acgatatcgc
     4081 gcagctggca ggaatgagtg agcaagagat tgcgctggcg gcagaggcgg ctcgcgagaa
     4141 aggtctggat aacaaatggc tgattccgct gctgaatacc acccaacaac cggcgcttgc
     4201 cgaaatgcgc gatcgtgcga cgcgtgaaaa actgtttatt gcgggctgga cgcgagcgga
     4261 aaaaaatgat gccaatgata cccgcgctat cattcaacgt ctggtggaga tccgtgcaca
     4321 acaggcaaca ctacttggtt ttcctcatta tgccgcatgg aaaatcgccg atcagatggc
     4381 aaaaacacct gaagcagcac ttaactttat gcgggaaatt gttccagcgg cgcgtcaacg
     4441 tgcgagcgat gaattagcct ccatacaggc ggttatcgat aagcagcagg gcgggtttag
     4501 cgcgcagccg tgggactggg cattttatgc ggaacaggta cggcgggaga aatttgatct
     4561 tgatgaggcg cagctcaagc catattttga attaaacacg gtgttaaatg aaggtgtatt
     4621 ctggaccgcg aatcagctct tcggtattaa gtttgtcgaa cgttttgata ttcctgtcta
     4681 ccatcctgac gttcgtgtgt gggaaatttt tgatcataat ggcgtggggc tggcgttatt
     4741 ttacggtgat ttcttcgccc gtgattcaaa aagcggcggt gcatggatgg gcaattttgt
     4801 tgagcaatca acgcttaata aaacacatcc ggtaatttat aacgtctgca attatcagaa
     4861 acccgctgcc ggtgagcctg cgttgttact ctgggatgat gtcataacct tattccatga
     4921 atttggtcat acgctgcacg gcctttttgc ccgccagcgt tatgccacgc tttccggcac
     4981 caacacgccg cgtgattttg tcgaatttcc gtcgcaaatc aacgaacact gggcaacgca
     5041 tccgcaggta ttcgctcgct acgcccggca ttatcagagc ggggcagcaa tgcctgacga
     5101 actgcaacag aaaatgcgta atgccagcct gttcaacaaa gggtatgaga tgagcgaact
     5161 gcttagcgcc gcacttctcg atatgcgctg gcattgcctg gaagaaaacg aagcaatgca
     5221 ggatgtcgat gattttgaat tgcgggcgct ggtggcggaa aatatggatc ttcctgctat
     5281 accgccacgc tatcgcagca gttatttcgc ccatattttt ggtggcggat atgctgcagg
     5341 ttattacgct tatctgtgga cgcaaatgtt ggccgatgat ggttatcagt ggtttgttga
     5401 gcagggcgga ttaacgcgtg aaaatgggct gcgttttcgc gaggcgatcc tttccagagg
     5461 taacagcgaa gatctggaac gcctgtatcg acaatggcgc ggtaaggcac ctaagattat
     5521 gccgatgctg caacatcgtg gcttgaacat ataaacacca ccaatggctg gcctgagata
     5581 tcgccaggcc agcctggtta tagcagtaat tgcagcagct gggcgagggc aaacctcacc
     5641 gctaaagcta ataccgtttc gcagtcgcca gcaaaatgca taaccgcagt gtagttctgg
     5701 cctttaatat gccacgcaaa ccagacggta cccgctggcg taccatcttc accgccctcc
     5761 ggtccgccgt agccggtaat ggcaatactg acatcagcat ccgcacgctc tatggcaccg
     5821 gttgccattt ctgctgccac tttctcactc accgcagaat atcgttcaag agattgctgg
     5881 cttacgctga ggattttcat ctttgcctga tcggtgaaag taacaaagcc tgcaccgtaa
     5941 aatttgggtg tatcttcagc tgcacacagg gcgctagcca acttaccgcc ggtgcatgat
     6001 tcggcggtag ttaagcgtaa ttgatccgcg ataagtcttt gactcaacgc ggatgtcagg
     6061 ttttcaatag tatcggtatc tacaagttgt acaattttat ctctattaat gttcactgtt
     6121 ttttgtccac gcttttatat gtaaaggt
//
LOCUS       DAPOAV010000159         6059 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.160, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000159 DAPOAV010000000
VERSION     DAPOAV010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6059
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.160"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..267
                     /locus_tag="RN951_004244"
     CDS             <1..267
                     /locus_tag="RN951_004244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707425.1"
                     /note="interacts RssB preventing the degradation of the
                     stress sigma factor RpoS; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraM"
                     /protein_id="HDX2529144.1"
                     /translation="KIKLIIWYQSDAFLPPESIFTLTHTGIMLNNKVLPVTIYNVVPF
                     NKTFWNLIKNSQECPTNTDNVLNECFNNRCTLQICPYGLKQQSP"
     gene            338..550
                     /locus_tag="RN951_004245"
     CDS             338..550
                     /locus_tag="RN951_004245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001333559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529145.1"
                     /translation="MPLHGAGCLPVNSVPAPESAIIPYTYSLITPPHRGIHHAKFFNK
                     LPAGQTIIASLNYEQRGILRENCFLQ"
     gene            complement(1039..1125)
                     /locus_tag="RN951_004246"
     CDS             complement(1039..1125)
                     /locus_tag="RN951_004246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3927 family protein"
                     /protein_id="HDX2529146.1"
                     /translation="MVDFSSRIMSVLSDGVLVAGVWLLLSRC"
     gene            complement(1215..1291)
                     /locus_tag="RN951_004247"
     tRNA            complement(1215..1291)
                     /locus_tag="RN951_004247"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1255..1257),aa:Arg,seq:tcg)
     gene            complement(1301..1376)
                     /locus_tag="RN951_004248"
     tRNA            complement(1301..1376)
                     /locus_tag="RN951_004248"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1341..1343),aa:Ile,seq:cat)
     gene            complement(1426..2475)
                     /locus_tag="RN951_004249"
     CDS             complement(1426..2475)
                     /locus_tag="RN951_004249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HDX2529147.1"
                     /translation="MLNTVKISSCELINADCLEFIRSLPENSVDLIVTDPPYFKVKPE
                     GWDNQWKGDDDYLKWLDQCLAQFWRVLKPAGSLYLFCGHRLASDIEIMMRERFSVLNH
                     IIWAKPSGRWNGCNKESLRAYFPATERILFAEHYQGPYRPKDAGYAAKGSALKQHVMA
                     PLISYFRDARAALGITAKQIADATGKKNMVSHWFSASQWQLPNESDYLKLQSLFARVA
                     EEKHQRGELEKPHHQLVDTYTSLNRQYVELQSEYKHLRRYFGVTAQVPYTDVWTHKPV
                     QFYPGKHPCEKPAEMLQQIISASSRPGDLVADFFMGSGSTVKAALALGRRAIGVELET
                     GRFEQTVREVQDLIV"
     gene            complement(2626..2823)
                     /locus_tag="RN951_004250"
     CDS             complement(2626..2823)
                     /locus_tag="RN951_004250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309806.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HDX2529148.1"
                     /translation="MLKQQDMTETARVVFNELSVTEPATVGEIAQNTYLSRERCQLIL
                     TQLVMADLADYQFGCYRRLPQ"
     gene            complement(3050..3871)
                     /locus_tag="RN951_004251"
     CDS             complement(3050..3871)
                     /locus_tag="RN951_004251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
                     /protein_id="HDX2529149.1"
                     /translation="MKLEDLPKYYSPKSPGLTDASASTSKDALSITDVMAAQGMTQNR
                     AEMGFSAFLGKMGISMNDRERATELLTEYALSRCDRVAALRKLPAEIKPAVMRIMASY
                     AFEDYARSAASKKQCSCCHGKKFIESEVFTNKIQYPDGKPPVWAKCTKGVYPSYWEEW
                     KKVREVVKVACPECGGKGEVSTACKDCRGRGVAIHREESVKRGMPVIRDCQRCGGRGC
                     ERLPSTEAFNAICKVTSAITLDTWKKSVKRFYDTLVVRFDIEEAWAERQLKRVTR"
     gene            complement(3868..4242)
                     /locus_tag="RN951_004252"
     CDS             complement(3868..4242)
                     /locus_tag="RN951_004252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDX2529150.1"
                     /translation="MLIDLVLPYPPTVNTYWRRRGSTYFISEEGKRYRRAVALIVRQQ
                     RLKLSLSGRLAIKVIAEPPDKRRRDLDNILKAPLDALTHAGLLIDDEQFDEINIVRGQ
                     RVPGGRLGVKIYPIMLEGQVKK"
     gene            complement(4255..5301)
                     /locus_tag="RN951_004253"
     CDS             complement(4255..5301)
                     /locus_tag="RN951_004253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HDX2529151.1"
                     /translation="MRVLLRPVLVPELGLVIVKPGRESMPVFHNTRVLVEPEPKSMRN
                     LSSGVVPAVRQPLAEDKSLLPFFSDERVIRAAGGAGALSDWLLRHVKSCQWPHGDYHH
                     SETVIHRYGTGAMVLCWHCDNQLRDQTSESLGQLAHQNLSAWMIDVILHAMNGSQERE
                     LSLAELSWWAVRNQVADALPEAVLRRSLGLRAEKIRSMYRESDIVPGEQTATSILKQR
                     TKNLAPLSHAHQQNPPQEETVVSIAVDPESPESFMKRPKRRRWVNEKYTRWVKTQPCA
                     CCGKPADDPHHLIGHGQGGMGTKSHDIFTLPLCREHHNELHADPLAFEEKHGSQVDLI
                     FRFLDHAFATGVLG"
     gene            complement(5303..5581)
                     /locus_tag="RN951_004254"
     CDS             complement(5303..5581)
                     /locus_tag="RN951_004254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529152.1"
                     /translation="MARNAKYYNHDNSTVLAHTHERYSHAFKSDWYQHPPCTEEQADW
                     LIQCYRRRGCEVKKALSLDYRHWIISVRLPYSERPPRPSRTFQQRIWR"
     gene            complement(5648..5899)
                     /locus_tag="RN951_004255"
     CDS             complement(5648..5899)
                     /locus_tag="RN951_004255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529153.1"
                     /translation="MMNIEELRKIFCEDGLYAVCVENGNIVSHYRIVCLQKNGAALIN
                     FVDARVTDGFILRDGEFVTSLQALKEIGIKAGFSAFSEE"
BASE COUNT         1505 a         1688 c         1376 g         1490 t
ORIGIN      
        1 aaaataaaat taataatctg gtatcaatcg gatgctttct tacctcctga aagtatattt
       61 acactgactc acacaggcat catgctcaat aacaaagtgc tacctgtaac catttacaac
      121 gtagtaccat tcaataaaac attctggaat ttaatcaaaa acagccagga atgccctaca
      181 aatacagata acgtattgaa tgaatgcttt aataaccgtt gcactctgca aatatgtcct
      241 tatgggctaa aacaacaaag tccataagga gtttactcac atctgacaaa atcaatataa
      301 acagcccctc cggagagggg ctggagagtg gcgctatgtg ccattgcatg gtgccgggtg
      361 cctcccggtg aattcagtac cagcacctga atccgcgatt atcccatata cctactcgct
      421 gattacccct ccgcacaggg ggattcacca tgcgaaattt tttaacaaac ttcccgccgg
      481 ccagacaata atcgccagcc tgaattatga gcaacgtggc attttacggg aaaactgttt
      541 tctgcagtaa aaaggcccgc cggagcgagc ctggaaggat agcggtcatg tgatgccggt
      601 ttcccggtaa ctcagcatcg gtatctgagt caacgttttc tctactgggt catttccgat
      661 acgttccgcc ttccggcaga ctttcatcac gtcagaaaat atagcaccct gagtaacagg
      721 acagtactca gaattcagga aactgtgaca catcctgcac agaaaagccc ctccggagag
      781 gggctgaagt atagcctaat ttctgtctgt cgcatggtgc caggggcctc ccggtaaatt
      841 cagcctgtct actgaatttg catgttctct ggatcataca ctttgccaga tgccccgccg
      901 ctgaggggga ttcaccatgc gatgtaattt ttaacaaatt ctccggcagc cagacaatca
      961 tcaagctgtg gaattgtgag gtatttaaaa atttcaacgg gtaactgata ccctgctaat
     1021 cgcctgatgc tttctttttc agcaacggga aagcaacaac cacacacccg ccaccaaaac
     1081 accatcagac agcaccgaca ttatccggct gctgaagtcc accatcacca ccagaaacaa
     1141 caggagtgca accacagctg cttagaaggc aattgctctg tccggctgag ctaacaacgc
     1201 agaataccga taaatggacc gccatcgaga actcgaaccc cgcgcaacca gcttcgaagg
     1261 ctggcgctct atcccgatga gctaatggtg gtatgtgata tggtggccct tgctggattt
     1321 gaaccagcga cctggcgatt atgagtcgct cgctctcacc actgagctaa agggccggga
     1381 gcagaataat aatggtgcgt aattaattct gcaatctcat ccgtttcaaa cgattaaatc
     1441 ctgaacttcc ctgactgtct gctcaaaacg tccggtctcc agctcaacgc caatcgcacg
     1501 acgcccgagc gccagtgccg cttttaccgt tgaacctgag cccataaaaa aatctgcaac
     1561 caggtcaccc ggacgactgc ttgcgctgat tatctgctgc agcatttctg ccggtttttc
     1621 gcacggatgt ttcccgggat agaactgcac cggtttatgt gtccacacat ccgtgtacgg
     1681 cacctgcgcc gtcacaccaa aataccgccg cagatgctta tattcactct gcagctccac
     1741 atactgccgg ttcagtgacg tatacgtatc caccagctgg tggtggggct tttccagttc
     1801 accgcgctga tgtttctctt ctgccacccg ggcaaacagc gactgtaatt tcagataatc
     1861 gctttcgttc ggtagctgcc actgactggc actgaaccag tgcgacacca tgtttttctt
     1921 tcctgtggca tctgcaatct gttttgccgt tatccccagg gccgcgcgcg catcacgaaa
     1981 gtaagaaatc agcggggcca tcacatgctg tttcagtgca ctgcccttcg ccgcataccc
     2041 ggcatctttc ggacgatacg gcccctgata atgttccgcg aacagaatgc gctctgtggc
     2101 ggggaaatac gcccgcaggc tttccttgtt gcatccgttc cagcgtccgg acggcttcgc
     2161 ccagataata tggttcagca cactgaagcg ttcacgcatc atgatttcga tatcagatgc
     2221 caggcgatga ccacagaaca ggtaaagact tccggcaggt ttcagcaccc gccagaactg
     2281 cgccagacac tggtccagcc acttcaggta atcatcgtcg cccttccact ggttatccca
     2341 gccctcaggc ttcactttaa agtacggcgg gtccgtgact atcaggtcaa cagaattttc
     2401 gggtaacgac cggataaatt ccaggcagtc ggcgttgatt aactcacaac tggatatttt
     2461 tacagtatta agcatggatc attaagcctg tctctgatag gctcattctg cttttgcgca
     2521 aagcagtggg cctgaggttt gcttgtgaac ccaacgcatg agcagatggc tggtgggtgc
     2581 ccctaacacc caccagccgc ccatttacca caaataaaaa agccttcact gcggaaggcg
     2641 tctgtaacaa ccgaactgat agtctgccag atccgccata accagctggg tcagtattaa
     2701 ctggcagcgt tcgcgtgaaa ggtaagtatt ctgcgctatc tccccgactg tcgccggttc
     2761 ggtaacgctt aattcattaa acaccactct ggcggtttct gtcatatcct gctgttttag
     2821 catgtctttt tcccttttcc ggttaacgtg acacaccaat aactcttgtc gaaaaagcca
     2881 gcaagctgaa agacaggtat tcaccgccac cagcgcgttt actatactga cgcgatttca
     2941 gtcataaaaa acccgccagg cggcggggtg taaaaaatct tctaacgtca ggcataaaac
     3001 gcccatcgtt agagcaaatt taccacagat tcgggaaaaa tcaacaacac tatcgcgtta
     3061 ccctctttaa ctgccgctcc gcccatgcct cttcaatgtc aaaccgaacc accaacgtat
     3121 cgtaaaagcg tttcactgat tttttccacg tatcaagcgt gatagcactc gtcactttgc
     3181 atatggcatt aaatgcctcc gttgatggta gtctttcaca gccacgacca ccacaacgct
     3241 ggcagtctct gataacaggc ataccacgtt ttaccgactc ttcacgatga atggcgacac
     3301 cacgcccacg gcaatcctta caggcggtgg aaacctcacc ctttccgcca cactccggac
     3361 aggcaacttt taccacctcc ctgacttttt tccattcttc ccagtaagac ggatacacac
     3421 ctttcgtaca ctttgcccat accggcggct taccatccgg atactggatc ttgtttgtaa
     3481 aaacctcgct ttcaataaat ttttttccgt gacagcagga gcactgtttt ttgctcgccg
     3541 cgctacgggc ataatcttca aacgcatacg aagccataat acgcatcact gccggtttta
     3601 tttctgccgg gagttttctt aacgccgcca cgcgatcaca ccgactgagt gcatattctg
     3661 tcagcaattc tgttgcccgc tctctgtcat tcatactaat gcccattttc ccaaggaacg
     3721 cagaaaaccc catctcagcc cgattctgtg tcatgccctg cgcggccatc acatcagtga
     3781 tactcagcgc atctttcgac gttgaggccg atgcatcagt caggccgggg gattttgggg
     3841 agtagtattt cggtaaatct tccagtttca ttttttgacc tgcccttcaa gcattatggg
     3901 gtaaatcttc acgcccagcc gccccccagg aacgcgctga ccgcgcacaa tattgatttc
     3961 atcaaactgc tcgtcgtcta tgagaagtcc ggcatgcgtc agcgcatcca gtggtgcttt
     4021 cagaatattg tccaggtcgc gacgacgctt atccggtggc tctgcaatca cctttatcgc
     4081 cagccttccg gacaggctta atttcagccg ctgctggcga acaataagcg ccacagcccg
     4141 gcgataacgc tttccctcct ccgagataaa atatgtgctg ccacggcgtc gccagtaagt
     4201 gttcaccgtc ggcgggtaag gtaaaaccaa atctatgagc atcagtcacc tcttttaccc
     4261 aagcacgcca gttgcaaagg cgtgatcaag aaaacgaaaa attaaatcaa cctgagaacc
     4321 atgcttttct tcgaacgcca gaggatccgc atgaagctcg ttgtgatgct cccgacacag
     4381 cggtagcgtg aaaatatcgt gagattttgt ccccattccg ccctgaccat gaccaatcag
     4441 gtgatgggga tcgtcggctg gcttaccaca acacgcacac ggctgtgtct tcacccagcg
     4501 tgtgtatttc tcgttaaccc agcggcgacg tttaggtcgt ttcatgaaag attccggaga
     4561 ctcaggatca acggcaatgc tgaccaccgt ctcttcctgt ggcgggtttt gctggtgggc
     4621 gtgagacagc ggcgcaagat tttttgtgcg ctgcttcagt atgctggtgg cggtctgctc
     4681 tcccggtacg atgtcgcttt cacggtacat tgagcggatt ttttccgcac gcaaccccag
     4741 cgaacgacgt aataccgctt ccggtagcgc gtccgccacc tgattgcgga ccgcccacca
     4801 ggataattca gccagcgata attcccgttc ctgcgagcca ttcattgcat ggagtatgac
     4861 gtcaatcatc catgcagaca ggttttggtg agcaagttgc ccgagtgatt cggaggtctg
     4921 gtcgcgcagc tggttgtcgc agtgccagca caacaccatt gcgccggtac cataacggtg
     4981 aatgacggtt tcactgtggt gataatcgcc gtgtggccac tggcaggatt taacatggcg
     5041 cagtaaccag tcagacaatg cgccagcgcc accagcagca cgaatcactc gttcgtcgct
     5101 gaaaaatggc agtaatgatt tatcctccgc cagcggctgg cgaacggcag gaacgacccc
     5161 ggacgacaga ttacgcatgc ttttcggttc cggctccacc agtacccggg tattgtggaa
     5221 taccggcatg gattcacggc ccggcttaac gatcaccagc ccgagttccg gtaccagaac
     5281 aggtcgaagt aatacccgca cgttacctcc agatacgttg ctggaatgtg cgggacggac
     5341 gcggtggccg ttcggagtaa gggagcctga cggagattat ccagtgacgg tagtcgaggc
     5401 taagggcttt tttaacctcg catccgcgcc tgcggtaaca ctgaatgagc caatcggcct
     5461 gttcttcagt gcatggggga tgctggtacc agtctgactt aaatgcatga gaataccgct
     5521 cgtgcgtgtg ggcaagaacg gtcgaattat catgattgta atattttgcg ttgcgtgcca
     5581 tcggttttct ccggtggcac ggtgttactc agcgggagtt cagccccgcg caagattgta
     5641 gatgagttta ttcttctgaa aaagcagaaa agccagcttt tattccgatc tctttcaatg
     5701 cctgtaatga agtgacaaac tcaccgtcgc gcaagataaa tccgtccgtc actcgggcat
     5761 ccacaaaatt aattaacgca gccccatttt tttgcaaaca cacaatgcgg taatgactaa
     5821 caatatttcc attttcaacg cacacagcat agaggccatc ttcacaaaaa attttacgca
     5881 gttcttcgat gttcatcatc agaatccttc cggataatta gctctcccct ttaagggacc
     5941 atccctctta tccctgcgcg ctacttaagt atttttgatt ctattccggc accgtccaga
     6001 acttcaaacg cgttgaaaat aaaaacaaaa acccgccgaa gcgggttaag tgcgggtgc
//
LOCUS       DAPOAV010000160         5961 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.161, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000160 DAPOAV010000000
VERSION     DAPOAV010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5961
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.161"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            102..1169
                     /locus_tag="RN951_004256"
     CDS             102..1169
                     /locus_tag="RN951_004256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001383880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta family protein"
                     /protein_id="HDX2529154.1"
                     /translation="MSQHQYYPQLKWKPAEYESLMLLDQTTLSGFTPIITIPDIDWDY
                     ENECYKKSLSSYLSDFGINLAASWKANRPVLLDVKYLDKHGSSRHHPLDMCIQDARVN
                     GKEIIPVVSPAYSTNYIHAVQRNLINGLAISITPQTWHQFTSLVNHLNIHPSLIDVII
                     DFGDIQNATDSLKQQALSMVNTLSGQAPWRNLILSSTAYPASQAGIPQHQVHHIPRHE
                     YDLWMYVVQNFSNGRTPSFSDYPTASSTITSVDPRFMSQYVSVRYSNDTSWIFVKGTA
                     VKGNGWGQTKNLCTTLVSSPEYQVFGSKFSWGDDYIYQRSLGANKSGGSKEWRKVAHT
                     HHITLVVRQLYWLAQTQPAKP"
     gene            complement(1111..1731)
                     /locus_tag="RN951_004257"
     CDS             complement(1111..1731)
                     /locus_tag="RN951_004257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7726 family protein"
                     /protein_id="HDX2529155.1"
                     /translation="MKDQDVRFAVHHKLLKESHLDPDCLVVDEFSISLGASRADIAVI
                     NGVIHGYELKSEYDSLERLPLQIKHYSSVMDKVTLVVAEKHLEGALKLIPGWWGVKTV
                     SVGPKGAILIKHMRGEKLNRNHDTLMLAQLLWKDECIDVLERWGYSKGIKSKPRFELW
                     NIIAENIPIANLRPEVRTALKKRVGWKVKAWQAESAPTNKAVSRLT"
     gene            complement(2148..2606)
                     /locus_tag="RN951_004258"
     CDS             complement(2148..2606)
                     /locus_tag="RN951_004258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009453323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HDX2529156.1"
                     /translation="MSRVAAIIYTLVICTIVCLSWAVNHYRDNAITYKAQRDKNAREL
                     KLANVVITDMQMRQRDVAELDARYTKELADANATIESLRADVSAGRKRLQVAATCAKS
                     TTGASSMGDGESPRLTADAELNYYRLRSGIDKITAQVNYLQEYIRTQCLK"
     gene            complement(2603..3136)
                     /locus_tag="RN951_004259"
     CDS             complement(2603..3136)
                     /locus_tag="RN951_004259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706619.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HDX2529157.1"
                     /translation="MSAKIKYGLSAAVLALIAAGASAPQILDQFLDEKEGNHTTAYRD
                     GSGIWTICRGATMVDGKPVIPGMKLSKEKCDQVNAIERDKALAWVERNIKVPLTEPQK
                     AGIASFCPYNIGPGKCFPSTFYKRLNAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQ
                     VIRRDQESALACWGIDQ"
     gene            complement(3192..3506)
                     /locus_tag="RN951_004260"
     CDS             complement(3192..3506)
                     /locus_tag="RN951_004260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdfR family protein"
                     /protein_id="HDX2529158.1"
                     /translation="MTQNYELIVKGIRNFENKVTVTLALRDKKRFDGEIFDLDISLDR
                     VEGAALEFYEAAARRSIRQVFMDVAAGLCEGDELLPETRPCSEARYTIKINSSDNSIT
                     GC"
     gene            complement(3511..3726)
                     /locus_tag="RN951_004261"
     CDS             complement(3511..3726)
                     /locus_tag="RN951_004261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II holin family protein"
                     /protein_id="HDX2529159.1"
                     /translation="MYQMEKITTGVSYTTSAVGTGYWFLQLLDRVSPSQWAAIGVLGS
                     LLFGLLTYLTNLYFKIREDRRKAARGE"
     gene            complement(3877..5733)
                     /locus_tag="RN951_004262"
     CDS             complement(3877..5733)
                     /locus_tag="RN951_004262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1737 domain-containing protein"
                     /protein_id="HDX2529160.1"
                     /translation="MAFKHYDVVRAASPSDLAEKLTHKLKEGWQPFGSPVAITPYTLM
                     QAIAAEGDVVVSGATEPEWYYVIVLAGQSNAMAYGEGLPLPDSYDAPHPRIKQLARRN
                     TVTPGGEVCVFNDIIPADHCLHDVQDMSTINHPRADLSKGQYGCVGQGLHIAKKLLPY
                     IPNNAGILLVPCCRGGSAFTQGTEGTFSESTGASQDSARWGVGKPLYQDLLFRTKAAL
                     QKNPKNVLLAICWMQGEFDMTNASYAQQPAAFLAMVQQFRADLAGLAAQCHGGSPASV
                     PWICGDTTYAWKQEHGTQYEVVYGAYKGKESQQIYFVPFMTDGSGVNTPTNNPSEDPD
                     IAGSGYYGSASRTNKNWVSSNRPTHFSSWARRGIIPDRMATAILNVAGRTLAFISGKA
                     PEIKPSPGGDTPSGPSDGDTSVRTVSLLPTAGEAAAQGWTITGGSVALEDGVFKVTKQ
                     SNKPWSLMHPVDDAVSLLTRGGRLSCKFRLSGALTNNQFGLGIYLYTDVALPDVVAMT
                     GTGNPFLMSFFTQTTDGKLNLMHHRKAGNTKLGEFGNYSNDWQTLELVFTAGSATVTP
                     KLNGVAGPAFQVIKDSLTLGLNALTLTDITKNAAYGVEIESLVLEINAPASS"
BASE COUNT         1556 a         1537 c         1274 g         1594 t
ORIGIN      
        1 gatatagctc aacttttccc aatgttttca agtgtataaa aacaattggc gttacgccat
       61 aacactatac ttaggataag taaagatttt aaggagtttt aatgagtcaa catcaatatt
      121 atccacagct gaaatggaag cctgctgaat atgaatctct gatgctttta gatcaaacta
      181 cgctctctgg ttttactccg atcattacca ttccagacat agactgggat tatgaaaacg
      241 aatgctacaa gaagagtttg agttcttact tatctgactt cggtattaac cttgcggcat
      301 cctggaaagc caatcgtcct gttttgctgg atgttaaata tttagataaa catggttcga
      361 gccgccatca tcctctagat atgtgtatcc aagatgctag agtaaatggt aaggaaatta
      421 tccctgttgt ttctcccgca tattcaacaa actatataca tgctgttcaa cgcaacttaa
      481 tcaatgggct cgctatatct atcacccccc agacatggca ccaattcaca agtctggtta
      541 accacttaaa tattcatcct agtttaattg atgtaatcat tgattttgga gatattcaaa
      601 acgcaactga tagtttaaaa caacaagcat taagcatggt caacacatta tcaggccaag
      661 ctccgtggag aaacttgatt ttatcttcaa ccgcataccc ggcatcacag gcagggatac
      721 cgcaacatca agttcatcat attccgcgcc atgaatacga tctttggatg tacgtagtac
      781 agaattttag caatggaaga acgccaagtt ttagtgatta tcccaccgct agctctacca
      841 ttacgagcgt agacccacgc ttcatgtctc agtatgtctc agtgagatat tcgaacgata
      901 cctcatggat ctttgtaaaa ggtaccgcag ttaaaggaaa tggatggggc caaactaaaa
      961 acttatgtac tacccttgtt agttcgccag agtatcaagt ctttggctcc aaatttagtt
     1021 ggggggatga ttacatttac caaagatcat taggcgctaa caaatctggc ggctctaaag
     1081 aatggcgtaa agttgcacat acgcaccata ttacgttagt cgtgagacag ctttattggt
     1141 tggcgcagac tcagcctgcc aagccttaac tttccagcct acgcgtttct ttaaggctgt
     1201 tctgacttca ggcctgagat tcgctattgg aatattttcc gcaataatat tccataactc
     1261 aaatcggggc ttgcttttga ttcctttgga atagccccat cgttcaagta cgtcgataca
     1321 ttcatctttc caaagcaatt gagcgagcat caatgtgtca tggtttcgat taagcttttc
     1381 tccacgcatg tgctttataa gaatggcgcc ttttggccca acagaaaccg ttttaacgcc
     1441 ccaccaacct gggattaact ttaatgctcc ctcaaggtgt ttctcagcta cgacaagagt
     1501 aaccttgtcc attacagaag aataatgctt gatttgaaga ggcaaacgct ccaaagagtc
     1561 atattcactt ttgagctcgt acccgtgtat aacaccattt attacagcaa tgtctgctct
     1621 actggcgcca agggatatgg aaaattcatc gaccacaagg cagtctggat ctaaatgcga
     1681 ttctttcaaa agcttatgat gcaccgcgaa cctaacatct tgatctttca tgacttctcc
     1741 ttactccctc cgttattgaa ttatagcgca ctgcatttta ctgcatttga gagatttgac
     1801 cacttcaatc acaaaatgct tatctgcagc aacaagattc atagccatac gactatggtg
     1861 attacctttt gtctggaaaa ctgaccattc cacgaagatc agataggtct atagaatctt
     1921 ggtttgtcat agcgttcgtc ttactttgag atgaaccttt gctgcatagg agatcagccc
     1981 gtcaaggctc accagcacta actgactact caaaggctca ttccaaaggg tttggttcga
     2041 cgtggttgag tgcgctgcgg tgcgcggtga aatacctgta caaaaatgcc ccgcatctgc
     2101 gaggcatttt cctgaaagtc acgtattaaa tttcagtgaa attaaaatta ttttaagcac
     2161 tgcgtcctga tgtactcctg caggtagttg acctgagcgg ttatcttgtc gattccactt
     2221 cggagacggt aataattgag ttcagcatct gctgtaagtc ttgggctttc tccatcgccc
     2281 atgctgctgg ctccggtcgt tgactttgca caggtggcgg cgacttgcag gcgcttacgc
     2341 ccagcagaaa catcagcacg aagactttcg atagtcgcgt tagcatcagc aagctccttt
     2401 gtgtatctgg cgtcgagttc tgctacatca cgctgacgca tctgcatgtc agtaattacc
     2461 acgttcgcca gcttcagttc tctggcattt ttgtcgcgct gggctttgta ggtaatggcg
     2521 ttatcgcggt aatgattaac agcccatgac aggcagacga tggtgcagat aaccagagta
     2581 taaataatcg ctgcgactct gctcactgat ctatccccca acaggctaat gcgctttcct
     2641 ggtcacgacg aataacctgt ccatagcagt tatttgaacg tatgcggcaa tcgcgcccac
     2701 catcttttat ccaccagcga atcgcctcgc atgcgccctt acgatcaccg gcattcagcc
     2761 gcttataaaa cgtcgacggg aaacacttac cggggccaat gttataggga cagaatgacg
     2821 ctatacccgc tttctgtggt tcggtcagtg gtactttaat attgcgctcc acccatgcca
     2881 gcgccttatc acgttcaata gcgttaacct ggtcgcattt ttccttcgac agcttcattc
     2941 ccggtatgac gggcttacca tccaccattg tggcaccacg acagatggtc catataccgg
     3001 aaccatcgcg gtatgccgta gtgtggttac cctctttttc atccagaaac tggtcaagta
     3061 tttgaggagc agacgcgcct gcagcaatca gcgccagaac agcagctgac aggccgtatt
     3121 tgatttttgc gctcatggat atttatcagg atgctaccaa tgaaagatac tggaaagcca
     3181 actgcaaaaa gctaacaacc cgtaatcgag ttatcagaac tgttaatttt tatggtatac
     3241 cgcgcctctg aacaggggcg cgtttctggc aacagctcgt ccccttcaca taacccggca
     3301 gcaacatcca tgaagacctg tctgatgctc cttctggctg ctgcctcata aaactccagc
     3361 gcggcacctt caacacggtc cagcgagatg tccaggtcaa aaatttcacc gtcaaagcgt
     3421 tttttgtccc gtaacgctaa agttaccgta actttattct caaaattgcg gatccctttc
     3481 acaatcagtt catagttttg agtcattgaa ttactctccc cgtgcagcct tacgacggtc
     3541 ctctctgatt ttgaaataca ggttagtcag atatgtcagc agcccaaaca gcagactccc
     3601 cagcacgcct attgccgccc actgagacgg ggaaaccctg tccagcaact gcaggaacca
     3661 gtagcccgtt cccaccgctg acgtggtgta tgacacacct gttgtgattt tttccatctg
     3721 gtacataccc cgtctcccgt tatccggaag ctgacaacaa taaaaaaagc caccagttaa
     3781 gtactgatgg ctctgataac tcatgcaggc atctcagacg acccactgac actaccggtg
     3841 agtttaacga taccttccat ttgactggct cactttttat gatgatgctg gtgcatttat
     3901 ctccagcacc agactttcta tctcaacgcc atacgctgca tttttggtaa tatccgtcag
     3961 cgtcagcgca ttcagcccca gtgtcagact gtcttttatg acctggaatg ccgggccagc
     4021 cactccattc agtttcggag taaccgtggc actgccggcg gtgaacacca gctccagcgt
     4081 ctgccagtcg ttactgtaat tcccgaactc gcccaacttt gtgtttcctg ctttcctgtg
     4141 atgcatcaga ttcagtttgc cgtctgtggt ctgggtgaag aacgacatca ggaacgggtt
     4201 accagtcccg gtcatcgcca cgacgtcagg taacgctaca tcggtataca gataaattcc
     4261 cagaccgaac tggttgttgg tcagtgcgcc tgacagtcga aacttacagc tcagtctgcc
     4321 accccgtgtc agcagggaga ctgcgtcatc caccggatgc atcagggacc aaggtttatt
     4381 gctctgcttg gtaaccttaa acacaccatc ttccagcgca acactgccgc cggtgatggt
     4441 ccagccctgc gcagcagcct ctccggctgt cggcagcagg gagactgtac gaacggatgt
     4501 gtcaccatca gacggccccg atggagtgtc gccgccgggc gagggtttga tttccggtgc
     4561 cttaccacta atgaaggcta aggtgcgacc ggctacgttc agaatagcag ttgccatacg
     4621 atcgggaata atgccacgac gcgcccatga gctgaaatgc gtcgggcgat ttgatgatac
     4681 ccagtttttg ttcgttcggg atgccgaacc gtaataacca gacccggcaa tatcaggatc
     4741 ttctgacggg ttgtttgtcg gtgtattaac tccgctacca tcggtcataa agggaacaaa
     4801 ataaatctgc tgggattctt tacctttata tgcaccatat accacttcat attgcgtacc
     4861 gtgttcttgt ttccacgcgt atgtcgtgtc gccacaaatc caggggactg atgccggact
     4921 tccaccgtga cactgcgccg ccagcccggc aaggtcagca cggaactgct gtaccattgc
     4981 aagaaatgct gctggctgct gggcgtaact ggcattcgtc atatcgaatt ccccctgcat
     5041 ccagcatatc gccagcaaaa cgtttttcgg atttttctgc aatgctgcct tcgtgcggaa
     5101 aagcagatcc tgatataacg gcttacccac tccccagcga gccgaatcct gactggcccc
     5161 cgtggactcg ctgaatgtcc cctccgtgcc ctgggtgaat gccgaaccac cacgacagca
     5221 tggtaccagc aggatccccg cgttattagg gatatacgga agcagttttt tggcaatatg
     5281 taagccctgt ccgacacagc cgtactgccc tttgctcagg tcagcccggg gatgattaat
     5341 cgtactcata tcctgaacat catgcagaca atggtcagca ggaatgatgt cgttaaatac
     5401 gcatacttca ccaccgggag tcactgtgtt acgacgggcc agttgcttaa tgcgcggatg
     5461 gggcgcatcg tatgaatccg gaagcggaag cccttcaccg taagccatgg cattggattg
     5521 cccggccagt acgatgacgt agtaccactc cggctcagtt gcaccactga cgaccacatc
     5581 accttctgct gcaatcgcct gcatcagggt ataaggggtt atggccaccg gactaccaaa
     5641 cggctgccag ccctctttca gtttatgtgt cagcttttcc gcaagatctg acggcgacgc
     5701 cgccctgaca acatcatagt gtttaaatgc catggttctt tccaccatct gaaaaatgat
     5761 tctttaaaat acctgacatg taatacagaa aaaacacaaa accatacctt aaataaaaac
     5821 ctcatcatca agcagatatg catggataaa ctacaagacg agatataaac caccctgcat
     5881 ttaaataaac aataaacaac atcagaaaaa taattctgct ctatggttta caatcaaaaa
     5941 tatcatttat acttttcaga a
//
LOCUS       DAPOAV010000161         5846 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.162, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000161 DAPOAV010000000
VERSION     DAPOAV010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5846
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.162"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(43..696)
                     /gene="fdnI"
                     /locus_tag="RN951_004263"
     CDS             complement(43..696)
                     /gene="fdnI"
                     /locus_tag="RN951_004263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit gamma"
                     /protein_id="HDX2529161.1"
                     /translation="MSKSKMIVRTKFIDRACHWTVVICFFLVALSGISFFFPTLQWLT
                     QTFGTPQMGRILHPFFGIAIFVALMFMFVRFVHHNIPDKKDIPWLLNIVEVLKGNEHK
                     VADVGKYNAGQKMMFWSIMSMIFVLLVTGVIIWRPYFAQYFPMQVVRYSLLIHAAAGI
                     ILIHAILIHMYMAFWVKGSIKGMIEGKVSRRWAKKHHPRWYREIEKAEAKKESEEGI"
     gene            complement(689..1573)
                     /gene="fdnH"
                     /locus_tag="RN951_004264"
     CDS             complement(689..1573)
                     /gene="fdnH"
                     /locus_tag="RN951_004264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase N subunit beta"
                     /protein_id="HDX2529162.1"
                     /translation="MAMETQDIIKRSATNSITPPSQVRDYKAEVAKLIDVSTCIGCKA
                     CQVACSEWNDIRDEVGHCVGVYDNPADLSAKSWTVMRFSETEQNGKLEWLIRKDGCMH
                     CEDPGCLKACPSAGAIIQYANGIVDFQSENCIGCGYCIAGCPFNIPRLNKEDNRVYKC
                     TLCVDRVSVGQEPACVKTCPTGAIHFGTKKEMLELAEQRVAKLKARGYEHAGVYNPEG
                     VGGTHVMYVLHHADQPELYHGLPKDPKIDTSVSLWKGALKPLAAAGFIATFAGLIFHY
                     IGIGPNKEVDDDEEDHHE"
     gene            complement(1586..4633)
                     /gene="fdnG"
                     /locus_tag="RN951_004265"
     CDS             complement(1586..4633)
                     /gene="fdnG"
                     /locus_tag="RN951_004265"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(4046..4048),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit alpha"
                     /protein_id="HDX2529163.1"
                     /translation="MDVSRRQFFKICAGGMAGTTVAALGFAPKQALAQARNYKLLRAK
                     EIRNTCTYCSVGCGLLMYSLGDGAKNAREAIYHIEGDPDHPVSRGALCPKGAGLLDYV
                     NSENRLRYPEYRAPGSDKWQRISWEEAFSRIAKLMKADRDANFIEKNEQGVTVNRWLS
                     TGMLCASGASNETGMLTQKFARSLGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWV
                     DIKNANVVMVMGGNAAEAHPVGFRWAMEAKNNNDATLIVVDPRFTRTASVADIYAPIR
                     SGTDITFLSGVLRYLIENNKINAEYVKHYTNASLLVRDDFAFEDGLFSGYDAEKRQYD
                     KSSWNYQFDENGYAKRDETLTHPRCVWNLLKEHVSRYTPDVVENICGTPKADFLKVCE
                     VLASTSAPDRTTTFLYALGWTQHTVGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSN
                     IQGLTDLGLLSTSLPGYLTLPSEKQVDLQSYLEANTPKATLADQVNYWSNYPKFFVSL
                     MKSFYGDAAQKENNWGYDWLPKWDQTYDVIKYFNMMDEGKVTGYFCQGFNPVASFPDK
                     NKVVSCLSKLKYMVVIDPLVTETSTFWQNHGESNDVDPASIQTEVFRLPSTCFAEEDG
                     SIANSGRWLQWHWKGQDAPGEARNDGEILAGIYHHLRELYQSEGGKGVEPLMKMSWNY
                     KQPHEPQSDEVAKENNGYALEDLYDANGVLIAKKGQLLSSFAHLRDDGTTASSCWIYT
                     GSWTEQGNQMANRDNSDPSGLGNTLGWAWAWPLNRRVLYNRASADINGKPWDPKRMLI
                     QWNGSKWTGNDIPDFGNAAPGTPTGPFIMQPEGMGRLFAINKMAEGPFPEHYEPIETP
                     LGTNPLHPNVVSNPVVRLYEQDALRMGKKEQFPYVGTTYRLTEHFHTWTKHALLNAIA
                     QPEQFVEISETLAAAKGINNGDRVTVSSKRGFIRAVAVVTRRLKPLNVNGQQVETVGI
                     PIHWGFEGVARKGYIANTLTPNVGDANSQTPEYKAFLVNIEKA"
     gene            4865..5746
                     /gene="yddG"
                     /locus_tag="RN951_004266"
     CDS             4865..5746
                     /gene="yddG"
                     /locus_tag="RN951_004266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415990.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid efflux DMT transporter YddG"
                     /protein_id="HDX2529164.1"
                     /translation="MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLS
                     GLLLIFTVGFPRIRQIPKGYLLAGSLLFVSYEICLALSLGYAATHHQAIEVGMVNYLW
                     PSLTILFAILFNGQKTNWLIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYF
                     LAFIGAFIWAAYCTVTNKYARGFNGITVFVLLTGASLWVYYFLTPQPEMIFSTPVMIK
                     LISAAFTLGFAYAAWNVGILHGNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGA
                     LMVCGGSLLCWLATRRG"
BASE COUNT         1330 a         1613 c         1435 g         1468 t
ORIGIN      
        1 cgccttttac agcgccattt tcagcttaaa gttcaaaaga gattatatcc cttcttcact
       61 ctcttttttc gcttctgcct tctcgatttc acgataccag cgcggatggt gtttcttcgc
      121 ccagcgacga cttaccttcc cttcgatcat ccctttaatc gatcctttca cccaaaatgc
      181 catatacata tggatcagga tggcgtggat caggatgata cccgcagccg cgtggatcag
      241 caggctgtag cgaacaacct gcatcgggaa gtactgcgca aagtacggac gccagataat
      301 caccccggtc accagcagca cgaaaatcat gctcatgatc gaccagaaca tcatcttttg
      361 cccggcgttg tacttaccga catccgccac tttatgctca ttgcctttca atacttcgac
      421 aatgttcaac agccacggaa tatctttctt atccgggatg ttgtgatgca caaaacgcac
      481 aaacataaac atcagtgcga cgaaaatcgc aatgccgaag aacgggtgca aaatgcgtcc
      541 catctgcggc gtaccgaagg tttgcgtcag ccattgcagc gtcgggaaga agaacgaaat
      601 cccggacagc gccaccagga agaagcaaat caccacggtc cagtgacagg cgcgatcaat
      661 aaatttggtg cgcacaatca ttttcgactt actcatgatg atcctcctcg tcatcgtcca
      721 cttccttatt cgggccaata ccgatgtagt ggaaaatcaa cccggcaaaa gtggcaataa
      781 agccagccgc tgccagcggt ttcaacgcgc ctttccacag gcttaccgag gtgtcgatct
      841 tcggatcttt cggcagaccg tgatacagct ccggctgatc ggcgtgatgc agcacgtaca
      901 taacgtgcgt accaccgacc ccttccgggt tgtagacgcc agcatgttcg taaccacgcg
      961 ctttcagttt cgccacgcgc tgttccgcca gctccagcat ctccttcttg gtgccgaagt
     1021 ggatagcccc ggtcggacag gttttcacac aagccggttc ctggccgacg ctgacgcgat
     1081 cgacgcagag cgtgcattta tatacccggt tatcctcttt gttgaggcgc ggaatattaa
     1141 acggacaccc ggcaatgcag taaccacagc cgatgcagtt ttccgactgg aaatcgacaa
     1201 tcccgttagc gtactgaatg attgcaccag cagacgggca cgccttcagg cagccgggat
     1261 cttcacagtg catacagccg tctttacgga tcagccactc cagcttgccg ttctgttcgg
     1321 tttcgctaaa gcgcatcacc gtccaggact tggcgctcag atcggcgggg ttatcgtaaa
     1381 ccccgacgca gtgccccact tcatcacgga tgtcgttcca ctccgaacac gccacctgac
     1441 aggctttaca gccgatacag gtggaaacgt cgataagttt tgcgacttct gctttgtaat
     1501 cacgcacctg agaaggcggc gtgatggagt tagttgcgga ccttttgata atgtcctgcg
     1561 tttccatagc catctgttcg cccccttacg ccttctcgat gttgactaag aacgctttat
     1621 attccggcgt ttgcgagttt gcatcaccga cattcggcgt cagagtgtta gcgatataac
     1681 ctttacgcgc gacaccctca aagccccagt ggattggaat acccaccgtt tcaacctgct
     1741 gaccatttac attcagcggt ttcagacgac gcgttaccac agccaccgcg cggataaagc
     1801 cacgcttgct ggagacagtg acacgatcgc cattattaat gcctttcgcc gccgccagcg
     1861 tttcgctgat ttccacaaac tgttccggct gagcaattgc gttgagcaat gcgtgcttgg
     1921 tccaggtgtg gaagtgctcg gtcagacgat aggtcgtacc cacatacggg aactgctctt
     1981 ttttacccat ccgcagcgcg tcttgttcat acagacgaac aaccgggtta gacaccacgt
     2041 tcggatgcag cgggttagtg cccagcggcg tttcaatcgg ctcgtagtgt tccgggaacg
     2101 gaccttccgc cattttgttg atggcaaaca ggcgtcccat cccttccggc tgcatgataa
     2161 acggcccggt tggcgtaccc ggtgcggcat tgccgaagtc aggaatatcg ttacccgtcc
     2221 acttgctgcc gttccactgg atcagcatcc gtttcggatc ccacggttta ccgttgatat
     2281 ccgccgaagc acggttgtac agcacgcgac ggttgagcgg ccacgcccag gcccatccca
     2341 gcgtattccc cagaccggac gggtcggagt tatcgcggtt agccatctgg ttgccctgct
     2401 ctgtccagct accggtgtag atccagcaag aagatgcggt tgtaccgtca tcacgcagat
     2461 gcgcaaagct actcagcaac tgacctttct tcgcaataag cacgccatta gcgtcataga
     2521 gatcttccag cgcgtagccg ttgttctctt tagccacttc gtcagattgc ggttcgtgcg
     2581 gctgcttgta gttccagctc atcttcatca gcggttctac gcctttacca ccttcggact
     2641 ggtacagctc gcgcagatga tggtagatac ccgccagaat ttcaccgtcg ttacgcgctt
     2701 cgcccggcgc gtcctgacct ttccagtgcc actgcaacca gcgaccggag ttagcgatag
     2761 aaccatcttc ttcagcaaag caggtcgaag gcagacggaa tacttcagtc tgaatagacg
     2821 ccggatcgac atcgttcgac tcaccgtggt tctgccagaa ggtagaggtt tcagtcacca
     2881 gcggatcgat aaccaccatg tacttcagct tgctcaggca gctcaccact ttgtttttgt
     2941 ccgggaagga cgcaaccggg ttaaagccct ggcagaaata accggtgact ttgccttcat
     3001 ccatcatgtt gaaatacttg atgacgtcgt aggtctggtc ccacttcggc agccagtcat
     3061 agccccagtt gttctctttc tgcgcggcat cgccatagaa agatttcatc aggctaacga
     3121 agaacttcgg atagttgctc cagtagttca cctgatcagc cagcgtcgct ttcggcgtgt
     3181 tcgcttccag atacgactgc aaatcaacct gtttttctga cggcagcgtc agataacctg
     3241 gcaggctggt agagagcagg cctaagtcag tcaagccctg aatgttggag tgaccacgca
     3301 atgcgttcac gccgccaccg gccataccca tgttaccgag cagcaactgg atcatcgcca
     3361 tagtacggat gttctgcgca cccacagtgt gctgcgtcca gcccagcgcg tacaggaagg
     3421 tggttgtgcg atccggtgcg ctggtggagg ccagcacttc acacactttc aggaagtcgg
     3481 cttttggcgt accgcagatg ttttcaacga cgtccggcgt gtagcgggaa acgtgctctt
     3541 tcagcaggtt ccacacacag cgcggatgag tcagtgtttc atcgcgtttc gcatagccgt
     3601 tttcatcgaa ctgatagttc caggacgatt tatcgtattg acgtttttca gcgtcgtagc
     3661 cgctgaacag accgtcttcg aaagcaaaat catcacgcac cagcaggctg gcgttggtgt
     3721 aatgcttaac gtattcggcg ttgattttgt tgttttcgat caggtagcgc aaaacgccag
     3781 acaggaacgt aatgtccgta ccggaacgaa taggcgcgta aatatccgcc acagaagcgg
     3841 tacgcgtaaa acggggatcg acaacgatca aggttgcgtc gttgttgttt ttcgcttcca
     3901 tcgcccagcg gaaaccgacg ggatgcgctt cagcagcgtt accgcccatc accatcacga
     3961 cgttagcgtt tttgatatcc acccagtggt tggtcatcgc accgcgacca aatgttggag
     4021 caagacttgc taccgttggt ccgtgtcaga cgcgcgcctg gttgtctacc gccagcatcc
     4081 cgagggagcg ggcaaatttc tgggtcagca tcccggtttc gttgctggca ccggaggcac
     4141 acagcatacc ggtagaaagc caacggttta ccgttacgcc ctgctcgttc ttttcaataa
     4201 agttagcgtc acggtcagct ttcatcagct tcgcaatacg ggagaatgct tcttcccagc
     4261 taatgcgctg ccatttgtca gaacctggcg cacgatattc cgggtagcgc agacggtttt
     4321 cactgttgac gtaatccagc aaaccggccc ctttcgggca cagcgcacca cggcttaccg
     4381 gatgatccgg gtcaccttca atgtgataaa tcgcttctct ggcgtttttt gcgccatcac
     4441 ccaggctata catcaatagc ccgcaaccta cggaacagta tgtgcaggtg ttacggatct
     4501 ctttagcgcg taataatttg tagtttcgcg cctgagccag tgcttgcttc ggggcaaagc
     4561 ccaatgccgc tactgttgtt ccagccatac cgcccgcgca gattttaaaa aattgtctgc
     4621 gactgacgtc cattgctttc ctcttttttc aggggtatta ctgcgcgagg aaactaacag
     4681 taaaattctg aatctttttg cgcgaaatca aaaagaacat ctgtttgcca caaaataatc
     4741 cgccttcgca aattgaccta cctcaatagc ggtagaaaaa cgcaccactg cctgacaggc
     4801 cagttaaaaa aatgctataa aattcagctt aatttttaac ggcaagagag acaaaacagc
     4861 gagcatgaca cgacaaaaag caacgctcat agggctgata gcgatcgtcc tgtggagcac
     4921 gatggtagga ttgattcgcg gtgtcagtga ggggctcggc ccggtcggcg gcgcagctgc
     4981 tatctattca ttaagcgggc tgctgttaat cttcacggtt ggatttccgc gtattcggca
     5041 aatcccgaaa ggctatttac tcgccgggag tctgttattc gtcagctatg aaatctgtct
     5101 ggcgctttcc ttagggtatg cggcgaccca tcatcaggcg attgaagtgg gtatggtgaa
     5161 ctatctgtgg cccagcctga caattctctt tgccattctg tttaatggtc agaaaaccaa
     5221 ctggttgatt gtacctggat tattattagc cctcgtcggc gtctgttggg tgttaggcgg
     5281 tgacaatggg ttacattatg atgaaatcat caataatatc accaccagcc cattgagtta
     5341 tttcctggcg ttcattggtg cgtttatctg ggcagcctat tgcacagtaa cgaataaata
     5401 cgcacgcgga tttaatggaa ttaccgtttt tgtcctgcta acgggagcaa gtctgtgggt
     5461 ttactatttt cttacgccac aaccagaaat gatatttagc acgcccgtca tgattaaact
     5521 catctctgcg gcatttacct taggatttgc ttatgctgca tggaatgtcg gtatattgca
     5581 tggcaatgtc accattatgg cggtaggttc gtattttacg cctgtacttt cctcagcgct
     5641 tgcagccgtg ctgctcagcg ccccgctgtc gttctcgttc tggcaaggcg cgctgatggt
     5701 ctgcggcggt tccctgctct gctggctggc gacacgtcgt ggttaaaata actgccgggt
     5761 ctacggcccg gtagttaatc agataaattc cgacaatatt aaaaaaataa atttcaaata
     5821 ccagtaattc accttatatc tcattt
//
LOCUS       DAPOAV010000162         5695 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.163, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000162 DAPOAV010000000
VERSION     DAPOAV010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5695
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.163"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            160..810
                     /gene="csgD"
                     /locus_tag="RN951_004267"
     CDS             160..810
                     /gene="csgD"
                     /locus_tag="RN951_004267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator CsgD"
                     /protein_id="HDX2529165.1"
                     /translation="MFNEVHSIHGHTLLLITKSSLQATALLQHLKQSLAITGKLHNIQ
                     RSLDDISSGSIILLDMMEADKKLIHYWQDTLSRKNNNIKILLLNTPEDYPYRDIENWS
                     HINGVFYSMEDQERVVNGLQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHRE
                     KEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR"
     gene            815..1204
                     /gene="csgE"
                     /locus_tag="RN951_004268"
     CDS             815..1204
                     /gene="csgE"
                     /locus_tag="RN951_004268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgE"
                     /protein_id="HDX2529166.1"
                     /translation="MKRYLRWIVAAEFLFAAGNLHAVEVEVPGLLTDHTVSSIGHDFY
                     RAFSDKWESDYTGNLTINERPSARWGSWITITVNQDVIFQTFLFPLKRDFEKTVVFAL
                     IQTEEALNRRQINQALLSTGDLAHDEF"
     gene            1229..1645
                     /gene="csgF"
                     /locus_tag="RN951_004269"
     CDS             1229..1645
                     /gene="csgF"
                     /locus_tag="RN951_004269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgF"
                     /protein_id="HDX2529167.1"
                     /translation="MRVKHAVVLLMLISPLSWAGTMTFQFRNPNFGGNPNNGAFLLNS
                     AQAQNSYKDPSYNDDFGIETPSALDNFTQAIQSQILGGLLSNINTGKPGRMVTNDYIV
                     DIANRDGQLQLNVTDRKTGQTSTIQVSGLQNNSTDF"
     gene            1672..2505
                     /gene="csgG"
                     /locus_tag="RN951_004270"
     CDS             1672..2505
                     /gene="csgG"
                     /locus_tag="RN951_004270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgG"
                     /protein_id="HDX2529168.1"
                     /translation="MQRLFLLVAVMLLSGCLTAPPKEAARPTLMPRAQSYKDLTHLPA
                     PTGKIFVSVYNIQDETGQFKPYPASNFSTAVPQSATAMLVTALKDSRWFIPLERQGLQ
                     NLLNERKIIRAAQENGTVAINNRIPLQSLTAANIMVEGSIIGYESNVKSGGVGARYFG
                     IGADTQYQLDQIAVNLRVVNVSTGEILSSVNTSKTILSYEVQAGVFRFIDYQRLLEGE
                     VGYTSNEPVMLCLMSAIETGVIFLINDGIDRGLWDLQNKAERQNDILVKYRHMSVPPE
                     S"
     gene            complement(2569..3060)
                     /locus_tag="RN951_004271"
     CDS             complement(2569..3060)
                     /locus_tag="RN951_004271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415554.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HDX2529169.1"
                     /translation="MNILLSIAITTGILSGIWGWVAVSLGLLSWAGFLGCTAYFACPQ
                     GGLKGLAISAATLLSGVVWAMVIIYGSALAPHLEILGYVITGIVAFLMCIQAKQLLLS
                     FVPGTFIGACATFAGQGDWKLVLPSLALGLIFGYAMKNSGLWLAARSAKTAHREQEIK
                     NKA"
     gene            complement(3162..3716)
                     /gene="ycdY"
                     /locus_tag="RN951_004272"
     CDS             complement(3162..3716)
                     /gene="ycdY"
                     /locus_tag="RN951_004272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone YcdY"
                     /protein_id="HDX2529170.1"
                     /translation="MNEFSILCRVLGSLYYRQPQDPLLVPLFTLIREGKLAANWPLEQ
                     DELLTRLQKSCDMTQVSADYNALFIGDECAVPPYRSAWVEGATEAEVRAFLSERGMPL
                     ADTPADHIGTLLLAASWLEDQSTEDESEALETLFSEYLLPWCGAFLGKVEAHATTPFW
                     RTMAPLTRDAISAMWDELEEDSEE"
     gene            complement(3740..4477)
                     /gene="ycdX"
                     /locus_tag="RN951_004273"
     CDS             complement(3740..4477)
                     /gene="ycdX"
                     /locus_tag="RN951_004273"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding phosphatase"
                     /protein_id="HDX2529171.1"
                     /translation="MYPVDLHMHTVASTHAYSTLSDYIAQAKQKGIKLFAITDHGPDM
                     EDAPHHWHFINMRIWPRVVDGVGILRGIEANIKNVDGEIDCSGKMFDSLDLIIAGFHE
                     PVFAPHDKATNTQAMIATIASGNVHIISHPGNPKYEIDVKAVAEAAAKHQVALEINNS
                     SFLHSRKGSEDNCREVAAAVRDAGGWVALGSDSHTAFTMGEFEECLKILDAVDFPPER
                     ILNVSPRRLLNFLESRGMAPIAEFADL"
     gene            complement(4532..5470)
                     /gene="ghrA"
                     /locus_tag="RN951_004274"
     CDS             complement(4532..5470)
                     /gene="ghrA"
                     /locus_tag="RN951_004274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415551.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrA"
                     /protein_id="HDX2529172.1"
                     /translation="MDIIFYHPTFDTQWWIEALRKAIPQARVRAWKSGDNDSADYALV
                     WHPPVEMLAGRDLKAVFALGAGVDSILSKLQAHPEMLNPSVPLFRLEDTGMGEQMQEY
                     AVSQVLHWFRRFDDYRIQQNSSHWQPLPEYHREDFTIGILGAGVLGSKVAQSLQTWRF
                     PLRCWSRTRKSWPGVQSFAGREELSAFLSQCRVLINLLPNTPETVGIINQQLLEKLPD
                     GAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHV
                     AAITRPAEAVEYISRTIAQLEKGERVCGQVDRARGY"
BASE COUNT         1545 a         1410 c         1302 g         1438 t
ORIGIN      
        1 tagattgaaa tcagatgtaa tccattagtt ttatatttta cccatttagg gctgatttat
       61 tactacacac agcagtgcaa catctgtcag tacttctggt gcttctattt tagaggcagc
      121 tgtcaggtgt gcgatcaata aaaaaagcgg ggtttcatca tgtttaatga agtccatagt
      181 attcatggtc atacattatt gttgatcact aaatcttctt tgcaggcgac agctctcttg
      241 cagcacctta aacaatcgct ggcaattaca ggaaaattac ataatattca acgttctctg
      301 gacgatatct cttcaggctc tattattctt ctggatatga tggaagcgga taaaaagctt
      361 atccattatt ggcaggatac tttgagcagg aaaaacaaca atatcaaaat attgttgcta
      421 aatacgcctg aagattaccc gtaccgcgac attgaaaact ggtctcatat caacggcgtt
      481 ttttattcca tggaggatca agaacgtgtt gtcaatgggt tgcaaggcgt cctgcgcggc
      541 gaatgctact ttacgcaaaa gcttgccagc tacctgatta cgcattcagg taactatcgt
      601 tataacagca cggaatcagc cctccttact catcgggaaa aagagatcct gaataagctg
      661 cgtatcggcg cgtctaataa cgagatcgct cgttcgttgt tcatcagcga aaatacggtt
      721 aaaacgcatc tttataatct tttcaagaag atagccgtaa aaaaccggac acaagcggtt
      781 tcctgggcaa acgataacct caggcgataa agccatgaaa cgttatttac gctggattgt
      841 ggcggcagaa tttctgttcg ccgcagggaa tcttcacgcc gttgaggtag aagtcccggg
      901 attgctaact gaccatactg tttcatctat tggccatgat ttttaccgag cctttagtga
      961 taaatgggaa agtgactata cgggtaactt aacgattaat gaaaggccca gtgcacgatg
     1021 gggaagctgg atcactataa cggtcaatca ggacgttatt ttccagactt ttttatttcc
     1081 gttgaaaaga gacttcgaga aaactgtcgt ctttgcactg attcaaactg aagaagcact
     1141 aaatcgtcgc cagataaatc aggcgttatt aagtacgggc gatttggcgc atgatgaatt
     1201 ctaaataaaa aattgttcgg aggctgcaat gcgtgtcaaa catgcagtag ttctactcat
     1261 gcttatttcg ccattaagtt gggctggaac catgactttc cagttccgta atccaaactt
     1321 tggtggtaac ccaaataatg gcgctttttt attaaatagc gctcaggccc aaaactctta
     1381 taaagatccg agctataacg atgactttgg tattgaaaca ccctcagcgt tagataactt
     1441 tactcaggcc atccagtcac aaattttagg tgggctactg tcgaatatta ataccggtaa
     1501 accgggccgc atggtgacca acgattatat tgtcgatatt gccaaccgcg atggtcaatt
     1561 gcagttgaac gtgacagatc gtaaaaccgg acaaacctcg accatccagg tttcgggttt
     1621 acaaaataac tcaaccgatt tttaagcccc agcttcataa ggaaaataat catgcagcgc
     1681 ttatttcttt tggttgccgt catgttactg agcggatgct taaccgcccc gcctaaagaa
     1741 gccgccagac cgacattaat gcctcgtgct cagagctaca aagatttgac ccatctgcca
     1801 gcgccgacgg gtaaaatctt tgtttcggta tacaacattc aggacgaaac cgggcaattt
     1861 aaaccctacc cggcaagtaa cttctccact gctgttccgc aaagcgccac ggcaatgctg
     1921 gtcacggcac tgaaagattc tcgctggttt ataccgctgg agcgccaggg cttacaaaac
     1981 ctgcttaacg agcgcaagat tattcgtgcg gcacaagaaa acggcacggt tgccattaat
     2041 aaccgaatcc cgctgcaatc tttaacggcg gcaaatatca tggttgaagg ttcgattatc
     2101 ggttatgaaa gcaacgtcaa atctggcggg gttggggcaa gatattttgg catcggtgcc
     2161 gacacgcaat accagctcga tcagattgcc gtgaacctgc gcgtcgtcaa tgtgagtacc
     2221 ggcgagatcc tttcttcggt gaacaccagt aagacgatac tttcctatga agttcaggcc
     2281 ggggttttcc gctttattga ctaccagcgc ttgcttgaag gggaagtggg ttacacctcg
     2341 aacgaacctg ttatgctgtg cctgatgtcg gctatcgaaa caggggtcat tttcctgatt
     2401 aatgatggta tcgaccgtgg tctgtgggat ttgcaaaata aagcagaacg gcagaatgac
     2461 attctggtga aataccgcca tatgtcggtt ccaccggaat cctgacagat aaaaaagccg
     2521 gaattatcat ccggcatttt actgtttaag cgaaagcgtg agtgcccctc acgctttatt
     2581 tttgatttcc tgctcacggt gcgccgtctt tgcactacgc gccgccagcc acaggccact
     2641 gtttttcatt gcgtaaccaa atatcagccc aagcgccagc gaaggtaaca ccagtttcca
     2701 gtcaccctgc ccggcaaacg tcgcgcatgc gcctataaac gtccccggaa caaatgaaag
     2761 cagcagctgt ttggcctgaa tacacatcag aaacgcgaca ataccggtta tgacataacc
     2821 gagaatttcc agatgtggtg ccagtgcact accgtaaata atgaccatcg cccacaccac
     2881 gccactaagc agggttgcag cggagatcgc cagccctttc agcccacctt gcgggcaggc
     2941 aaagtaggcc gtacagccca ggaagcccgc ccagcttagt aagcccaggg aaacagccac
     3001 ccatccccag ataccggaga gaatgcctgt tgtgattgca atagagagaa gtatgttcat
     3061 gccgcgcatg atagcagaaa acgcggccat gaatgagatc gagcacacat tttatgcaac
     3121 aacaaattat ccgttgcagt tatgagtgac gtagatcaca cttattcttc agaatcttct
     3181 tccagctcgt cccacattgc actaatggca tcgcgggtta gcggtgccat ggtgcgccag
     3241 aaaggcgtgg ttgcatgggc ctccactttg ccaaggaacg caccacacca gggtaacaga
     3301 tactcactga acagtgtttc cagtgcttcg ctctcatctt ccgttgactg atcttccagc
     3361 caggaagctg cgagcagcaa tgtgccgatg tgatcggctg gcgtatccgc taatggcatc
     3421 cctcgctcag aaagaaaagc gcgcacttcc gcttccgtcg cgccctcaac ccatgcgcta
     3481 cgatatggcg gcacagcaca ttcatcgccg ataaacaacg cattgtaatc ggcagagact
     3541 tgcgtcatat cacagctttt ctgcaaacgt gtcagcaact catcctgctc cagtggccag
     3601 ttcgcagcca gtttcccctc acgaatcagg gtaaacagcg gcaccagtaa aggatcttgt
     3661 ggttggcggt aatagagcga acccagcaca cgacagagga tagaaaactc gttcattaat
     3721 atatttccat tactagtaat taaaggtctg caaattccgc aatcggtgcc ataccgcgag
     3781 attcaaggaa gttcagtaag cggcgcggag aaacattcaa aatgcgctct ggcggaaaat
     3841 ctaccgcgtc gaggatttta agacactctt caaattcccc catggtaaac gcggtgtgag
     3901 aatccgagcc taatgccacc caacctccag catcacgtac cgctgcggct acctcacgac
     3961 agttgtcttc actgccctta cgtgagtgta aaaatgagga attattgatt tccagcgcca
     4021 cctgatgttt cgcggctgct tcagcaacgg ctttcacatc tatttcatat ttgggatttc
     4081 cgggatggct tattatatgc acattgccgc tggcgatagt ggcgatcatc gcttgtgtat
     4141 tggtcgcttt gtcatgtggc gcaaaaaccg gctcatgaaa accggcaata attagatcca
     4201 gcgagtcaaa cattttaccg ctgcagtcaa tttcaccatc aacattttta atgttagctt
     4261 cgatgccgcg caggatccct accccatcaa ccactcgcgg ccagatacgc atgttaatga
     4321 agtgccagtg atgcggcgca tcttccatat ccgggccatg atcggtgatc gcaaaaagtt
     4381 taatgccctt ttgtttggcc tgggcaatgt aatcacttaa tgtgctatat gcatgtgtgc
     4441 tggcaacggt atgcatatga aggtcgacgg gatacataac tctctcctgt attcaattcc
     4501 cgccaaggat agcaggaatc ctgatgcttt attagtagcc gcgtgcgcgg tcgacttgcc
     4561 cgcagaccct ctcccctttt tcgagctggg caatggtgcg agaaatgtac tccacagctt
     4621 cagcgggacg ggtaatcgcg gcgacatgtg gtgttatcgt cacgcgtgga tgttgccaga
     4681 gcggactttc aggcggtaag ggttcacgat taaaaacatc caacattgcg cctttaactt
     4741 tgccgctatc cagcgccgcg agcaggtcat cttccacaac atgaacacca cgcgccaggt
     4801 tgaggagata cgcgccatcc ggtaattttt cgagtaattg ttgattaata atgccgacgg
     4861 tttcaggggt attcggtaac aaattaatca atacccgaca ttggctcaga aatgcagaca
     4921 gttcttcccg tccggcaaag ctttgcacgc caggccacga tttacgggtt cgactccagc
     4981 aacgcagcgg aaagcgccag gtttgcagac tctgagcaac tttactgccc agtacgcctg
     5041 cgcccaaaat gccgatggta aaatcttccc gatgatattc aggcagcggt tgccaatgcg
     5101 aactattttg ctggatgcga taatcgtcaa aacgtcgaaa ccaatgcagc acctgactga
     5161 cagcatattc ctgcatttgc tcgcccatac cggtatcttc caggcgaaaa agtggaacag
     5221 aagggttcag catttcaggg tgtgcctgta gcttgctcaa aatagaatca acaccggccc
     5281 cgagtgcgaa caccgcttta agatcgcgcc ctgccagcat ttcaacagga ggatgccaga
     5341 ctaaagcata atcagcagag tcattatctc cgcttttcca tgctctgact cttgcctgag
     5401 gaatagcttt gcgcagtgcc tcaatccacc attgggtatc gaacgttggg tgataaaaga
     5461 tgatatccat actgactccc gaaaagcgtt gtgcgaaatt tattcgcact tatcgttatg
     5521 atctacaaag gccaccagca taacaaatcc gtggtcggtg gcaaaaaaag cagatttcgc
     5581 ttattaaaac cacacattga ttgaagtttg aataaacgcg cgattttttc aaaaagtttg
     5641 ttgacctcag gtcatgattt ccctaaatta gcgcccgttc cagcaagaca ggaac
//
LOCUS       DAPOAV010000163         5620 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.164, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000163 DAPOAV010000000
VERSION     DAPOAV010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5620
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.164"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(40..159)
                     /locus_tag="RN951_004275"
     CDS             complement(40..159)
                     /locus_tag="RN951_004275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010617445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage virion morphogenesis protein"
                     /protein_id="HDX2529173.1"
                     /translation="MARVHHYGLRDRLVRGGEDVRYEARPLMGINNETMGKIE"
     gene            complement(171..554)
                     /locus_tag="RN951_004276"
                     /pseudo
     CDS             complement(171..554)
                     /locus_tag="RN951_004276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001395480.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            639..833
                     /locus_tag="RN951_004277"
     CDS             639..833
                     /locus_tag="RN951_004277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529174.1"
                     /translation="MPRSFLDLCNLRLLVVILVVLTASQFRFSLLISHLKAKAIPVRG
                     AKFKKACFRAGFLLSNYQRS"
     gene            complement(830..1765)
                     /gene="ldtA"
                     /locus_tag="RN951_004278"
     CDS             complement(830..1765)
                     /gene="ldtA"
                     /locus_tag="RN951_004278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HDX2529175.1"
                     /translation="MMRRVNILCSFALLFASQNSLAVTYPLPPEGSRLVGQSLTVTVP
                     DHNTQPLETFAAQYGQGLSNMLEANPGADVFLPKPGSQLTIPQQLILPATVRKGIVVN
                     VAEMRLYYYPPDSNTVEVFPIGIGQAGRETPRNWVTTVERKQEAPTWTPTPNTRREYA
                     KRGESLPAFVPAGPDNPMGLYAIYIGRLYAIHGTNANFGIGLRVSQGCIRLRNDDIKY
                     LFDNVPVGTRVQIIDQPVKYTTEPDGSNWLEVHEPLSRNRAEYESDRKVPLPVTSSLR
                     AFINGQEVDVNRANAALQRRSGMPVQISSGSRQMF"
     gene            complement(1827..2906)
                     /gene="cobT"
                     /locus_tag="RN951_004279"
     CDS             complement(1827..2906)
                     /gene="cobT"
                     /locus_tag="RN951_004279"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HDX2529176.1"
                     /translation="MQILADLLNTIPAIDSAAMSRAQRHIDGLLKPVGSLGKLEALAI
                     QLAGMPGLNGIPHVGKKAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVL
                     AAQAGANVHVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRRQAEKLLLDVICYT
                     RELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVVGIGANLPTDKLANKIDVV
                     RRAITLNQPNPQDGIDVLAKVGGFDLVGIAGVMLGAASCGLPVLLDGFLSYAAALAAC
                     QMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMDMRLGEGSGAALAMPIIEAACA
                     IYNNMGELAASNIVLTGNTTSDLNS"
     gene            complement(2918..3661)
                     /gene="cobS"
                     /locus_tag="RN951_004280"
     CDS             complement(2918..3661)
                     /gene="cobS"
                     /locus_tag="RN951_004280"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HDX2529177.1"
                     /translation="MSKLFWAMLSFITRLPVPRRWSQGLDFEHYSRGIITFPLIGLLL
                     GAISGLLFMVLQAWCGAPLAALFSVLVLALMTGGFHLDGLADTCDGVFSARSRDRMLE
                     IMRDSCLGTHGGLALIFVILAKILVLSELALRGEPILASLAAACAVSRGTAALLMYRH
                     RYAREEGLGNVFIGKIDGRQTCVTLGLAAIFAAVLLPGMHGVAAMVVTMVAIFILGQL
                     LKRTLGGQTGDTLGAAIELGELVFLLALL"
     gene            complement(3658..4203)
                     /gene="cobU"
                     /locus_tag="RN951_004281"
     CDS             complement(3658..4203)
                     /gene="cobU"
                     /locus_tag="RN951_004281"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HDX2529178.1"
                     /translation="MMILVTGGARSGKSRHAEVLIGDSSQVLYIATSQILDDEMAARI
                     EHHRQGRPEHWRTVERWQHLDELIHADINPNEAVLLECVTTMVTNLLFDYGGDKDPDE
                     WDYHAMEQAINAEIQSLIAACQRCPAKVVLVTNEVGMGIVPESRLARHFRDIAGRVNQ
                     QLAAAANEVWLVVSGIGVKIK"
     gene            5256..5504
                     /locus_tag="RN951_004282"
                     /pseudo
     CDS             5256..5504
                     /locus_tag="RN951_004282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612015.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1516 a         1500 c         1234 g         1370 t
ORIGIN      
        1 aagctattgc catcacaaaa tcaagttatt aattatgatt tattcaatct tccccattgt
       61 ttcattattt atacccatca gcggcctggc ctcataccgc acatcttcgc ccccacgcac
      121 cagccgatcc cgcaacccat aatgatgcac ccgcgccatg cgctgcaccc gtgtaactga
      181 cacccagtta tctcattgat ttttattgcc agaagctctg agctccagcg tgatcgctgg
      241 tagccaaaat cgccgggagc atgttttacc agctcacgta ataacatgca gatatgctca
      301 aaaggccagc gacgggcaca cccggcaggt aatgatttca gtcctgcaac acccgacagc
      361 gtgaaccagt taatccagcg gccgacggag gaacgggcac agcaaagcgt tctggcaacg
      421 tcgctgacgc gacagccgcg gtgcatcatc agcatggcag tcagccgacg ggcataattt
      481 ttatcgtgcg ttttatggat cgctttctgc atcaggcgtc gttcgtcacg gggaattggt
      541 gctatgatcg gcatcactca gtccggtcag tgatattggt tggtttggcg atgatcagat
      601 cgcacaatcc gggctgagtt cactcaaagt gatctactat tccgcgcagc tttttagatt
      661 tatgtaacct tcgcctattg gtggtcattt tggtggtctt gacagcatcg caattcaggt
      721 ttagcttact tattagccac ttaaaggcaa aagcgatccc agtcagagga gccaaattca
      781 aaaaagcctg ctttcgagca ggctttttgc tttctaatta ccagcgctct taaaacatct
      841 gtcttgaacc agaactaatt tgcacaggca tccccgatcg acgttgcaac gcagcatttg
      901 cgcgatttac atcaacttct tgcccgttga taaacgcccg caaagatgag gttacaggca
      961 atggcacttt tcggtcagac tcatattctg cacgattgcg cgacaacggc tcatgaactt
     1021 ccagccagtt cgagccatct ggttcagtgg tgtattttac tggctggtcg ataatttgca
     1081 cacgcgtccc aacaggaaca ttatcaaaca gatatttgat atcgtcattg cgcagacgaa
     1141 tacagccctg acttacccgg agcccaatac caaaattggc attggtacca tggatggcat
     1201 acaacctgcc aatataaatc gcgtacagcc ccatgggatt atcgggaccc gcaggaacaa
     1261 atgcgggcaa actctcccct cgtttcgcat attcgcgccg ggtgttcggc gttggcgtcc
     1321 aggttggagc ttcttgttta cgttcaacgg tagtcaccca gttacgcggg gtttctcgcc
     1381 cagcctggcc gataccaata ggaaagactt ccacagtatt actgtctggt gggtagtaat
     1441 aaagacgcat ctcagcgacg ttaaccacaa tccctttacg aacagtggcg ggcaaaatca
     1501 gttgctgcgg aatggtgagt tgtgagccag gcttcggcaa aaaaacatca gcgcccggat
     1561 tcgcttccag catattactt aacccttgcc cgtattgtgc ggcaaaagtc tccagcggct
     1621 gagtattgtg atcaggaaca gttacagtaa gcgactgccc cactaaacgg ctaccctctg
     1681 gaggtaatgg ataagttacc gccaggctat tttggctggc aaaaagcaga gcaaatgagc
     1741 aaagaatatt tacacgacgc atcatgtccc tttcctaagt cgcgaatact atccgataag
     1801 tatagctttt atcagacttt tcgtttttag ctgttcaaat cagaagtcgt attccccgtt
     1861 agaacaatat tactggcagc aagttcgccc atgttgttgt atatcgcaca agcagcttcg
     1921 atgatgggca tcgccagagc tgcaccactc ccctcaccta aacgcatatc catattgaga
     1981 taaggctcca gccccaaatg cgagagcgct atacgcgcgc ctttttctgc cgacaagtga
     2041 gaaggaatga gatacggttt gattgcagga gacatctggc aggctgcgag cgcagcagca
     2101 taagaaagaa atccatccag caacacgggt aaaccgcagg aagcagcacc taacatcact
     2161 ccagctattc cgaccaaatc aaatccaccc acttttgcca ggacatcaat accatcctga
     2221 ggatttggtt gattcaacgt aatcgcccga cgcacaacat caattttatt agccagttta
     2281 tctgtcggca ggtttgcgcc aatcccaacc acttcttcag gatcccggcc agtgattgtg
     2341 ctgactattg ccgctgccgg tgtcgtgttt gccatcccca gttcacctac accaaacagc
     2401 gtgacaccgt tttttgccag ctcccgcgta taacatatga cgtccaaaag caacttttca
     2461 gcctgacggc gactcattgc cggagctgaa gcaatattgc cgctacctcg tgcgacacgc
     2521 atgttgataa gcccggggat aggctcagca gtatcaatac caacatcaat tacgtggacg
     2581 ttagcgcccg cttgtgctgc cagcacacac acgccggttg ttccacgggt catattttca
     2641 gcctgtatgg ctgtcacttc ttttggagaa atagcgaccc cttcctccca gacgccgtga
     2701 tcggcacaca taaccagtac cgcttttttg cccacatgcg gtatgccatt caaccccggc
     2761 attcctgcca gttgtatggc aagcgcctcc agctttccca ggctaccaac aggtttgagt
     2821 aacccgtcaa tatgccgttg tgcacgcgac atagcggcag aatcgatggc tgggatcgta
     2881 ttcagtaaat cggcaagtat ttgcatgtca cgtctcttta tagcagtgcc agcaggaaga
     2941 ccagttcacc aagctctatg gctgctccca gcgtatcgcc cgtttgcccg cccagcgtac
     3001 gtttgagaag ctgaccgagg atgaaaatcg ccaccatcgt caccaccata gcagccacac
     3061 catgcatacc cggcaataat acggcagcaa aaatagcggc taagccgagt gtgacgcagg
     3121 tttgtcgccc atcaattttg ccaatgaaca cattgccaag tccttcttcc cgcgcataac
     3181 gatgacgata catcaataat gcggcagtcc cgcggctgac cgcacatgct gccgccagcg
     3241 atgcaaggat cggttcgcca cgcagagcca actcgcttaa caccagaatc tttgccagta
     3301 tcacaaaaat caatgccaga ccgccgtggg tgcctaaaca gctatcacgc atgatttcca
     3361 acatgcgatc gcggctacgt gcagaaaata cgccatcaca ggtatcagcg aggccgtcca
     3421 gatggaatcc cccggtcatc agcgccagca caagtacgct aaacagtgcc gccagtggtg
     3481 cgccacacca tgcctgcagc accatgaaga gcagcccgct aatcgcgcca agcaataatc
     3541 caatcaaagg aaaagtaata ataccgcgag aataatgctc gaaatccagt ccctgggacc
     3601 agcgacgcgg tacaggcaga cgcgtaataa atgagagcat cgcccaaaat aatttactca
     3661 tttgattttt actccaatac ccgaaaccac cagccatact tcatttgccg cagcggccaa
     3721 ctgctgattt acccgcccgg caatatcacg aaaatgtcgt gccagacgac tctccggcac
     3781 aatccccatt cccacttcgt tagtcactaa tacaaccttt gcggggcaac gttggcaggc
     3841 agcaatcaac gactgaatct cagcattaat cgcctgttcc atcgcgtgat aatcccattc
     3901 atcagggtct ttatcgccgc cataatcaaa caacagatta gtcaccattg tggtaacgca
     3961 ttccagcaac acagcctcat tcgggttaat gtctgcatga attaattcat caagatgttg
     4021 ccagcgctcc actgtgcgcc agtgctccgg gcggccttgc cgatgatgtt ctatccgtgc
     4081 agccatctca tcatcaagga tttgcgaggt agcgatatac agaacctgtg aagagtcccc
     4141 aataagcacc tctgcgtggc gactcttccc gctccgtgcg ccccccgtca ccaaaatcat
     4201 cataccgact cctgattcaa atgtatgatg gtattcattg aacagaacaa tggatccccc
     4261 accgttgctg accgcaaaac atttacgcga ttaatactgc gcgtaatata attaaaaatc
     4321 cagcattctc aatccattac gaaataagat ggcattacgg aatagccaga ctttctcgtg
     4381 ttaacgtccg acaaaatgcg tcattgacag cggtttctgt ggattgacac atttcattca
     4441 gataatgaat taatgctact gccggaccaa ccagcaaacg ggcattgtgt tctgaaatct
     4501 aggctattga ttcaacgtca gcgacagatc tgcgctgtaa aagaacttgt aaaacaacgc
     4561 aatagaatta tccggaatgg tggcgactat gcactagaac accacaattt cgctctctcg
     4621 gtaaggcact gtcacagcat tcaacagaat gtgacttgcc agatttatta gcgccaccag
     4681 atgtttaacc aggtaaccac gacccagtcg gggatatatt ccatcttctc gctgacatca
     4741 tcaagaataa aaaggtttat cacactcaga gcaacgttct tcagcaggcg ggataattct
     4801 tcaacattta gaagatgtgt tattaaaggc atacaaactg gacgtattgt attttctttt
     4861 ggtggttgac ctaaggtagc agtttatcct gatgcgctga gatttctgta atatctacgt
     4921 caacattctc ctcgaataga aaatgcagcc ccggcaagtg attcacattt tttaacaaaa
     4981 cgttgttagc gtgccatttt cagaagctct ccaagaaagc gaattctttt ctcaaattct
     5041 gcattctcag acacagcttt ctactccatg gcaatggccc aaatacgaag ttgctcagga
     5101 tcattagtgg tgctgagaag ttaaataacc atgcggagta ccactcgtca tcacgtattt
     5161 atatatcatg aagctattgt tgtgttttgt actgaatcgc cacgggttta acagacacct
     5221 cagagtcatt taagatggct taaagagagg tgcccatgag cggtaagcgt tatcccgaag
     5281 agtttaaaac tgaagcagtc aaacaggttg ttgatcgcgg ttattctgtt gccagcgttg
     5341 caacacgtct cgatatcacc acccacagcc tttatgcctg gataaagaag tacggtccgg
     5401 attcttccac taataaagaa cagtcagatg ctcaggccga gatccgccgt ctccagaaag
     5461 agctgaaacg ggttaccgac gaacgggaca tattaaaaaa agccgctgta gattcaattg
     5521 gtcaacgcaa cagttatgtg aaaacatggg gttgcggagg ttttttgaat gagacgaaca
     5581 tttacagcag aggaaaaagc ctctgttttt gaactatgga
//
LOCUS       DAPOAV010000164         5591 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.165, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000164 DAPOAV010000000
VERSION     DAPOAV010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5591
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.165"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            98..391
                     /locus_tag="RN951_004283"
                     /pseudo
     CDS             98..391
                     /locus_tag="RN951_004283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611607.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            492..1304
                     /locus_tag="RN951_004284"
     CDS             492..1304
                     /locus_tag="RN951_004284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032492661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="subclass B1 metallo-beta-lactamase NDM-5"
                     /protein_id="HDX2529179.1"
                     /translation="MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQ
                     RFGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLLVDTAWTDDQTAQIL
                     NWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGLVAAQHS
                     LTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSL
                     GNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR"
     gene            1308..1673
                     /gene="ble"
                     /locus_tag="RN951_004285"
     CDS             1308..1673
                     /gene="ble"
                     /locus_tag="RN951_004285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bleomycin binding protein Ble-MBL"
                     /protein_id="HDX2529180.1"
                     /translation="MADHVTPNLPSRDFDVTEAFYAKLGFATSWKDRGWMILQRGGLQ
                     LEFFPYPDLDPATSSFGCCLRLDDLDAMVALVNAAGAEEKSTGWPRFKAPQLEASGLR
                     IGYLIDPDCTLVRLIQNPD"
     gene            1678..2316
                     /locus_tag="RN951_004286"
     CDS             1678..2316
                     /locus_tag="RN951_004286"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HDX2529181.1"
                     /translation="MPAKIKICGISTPEALDATIAARADYAGLVFYPASPRAVTSNVA
                     GALTSRAAGQIAMVGLFVDADDAVIADALVAAKLNALQLHGSESPERVAQLRARFGKP
                     VWKALPVASASDVARAAAYAGAADLILFDAKTPKGALPGGMGLAFDWSLLAGYRGALP
                     WGLAGGLNPTNVAEAIARTGAPLVDTSSGVESAPGVKDTDKITNFAFAVRLA"
     gene            complement(2327..3358)
                     /locus_tag="RN951_004287"
     CDS             complement(2327..3358)
                     /locus_tag="RN951_004287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD N-terminal
                     domain-containing protein"
                     /protein_id="HDX2529182.1"
                     /translation="MTASTIRLRRWLAGLALLLALPATSAVAQDFELPPVDEVFVLSA
                     QATAPDRIEVRWRIADGYYLYRHRTSVKADAAFTGATMALPKGKAYRDEFFGDVETYR
                     KELLGTLTGTPAAGASATTLTVKYQGCADAGVCYPPQTRTLKVALPGEAGAGGFGCKA
                     RGLHDYVVKNGSADHPNAEVKFALGDVVNTMIGCTNGETIMLCHDTSLPRPYSLGFRV
                     QGTEGLWMDVNKSIYLEGKSPQPHRWEPAEGWFAKYDHPLWKRYADLAAGAGHGGMDW
                     FVIHAFVEALKAKAPMPIDIYDALAWSAITPLSEQSIAEGNRTLDFPDFTRGQWRTRK
                     PIFALNDAY"
     gene            complement(3671..5212)
                     /locus_tag="RN951_004288"
     CDS             complement(3671..5212)
                     /locus_tag="RN951_004288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000050481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="HDX2529183.1"
                     /translation="MSLARNATASQSPTQTNGYERHQPDQTLLYQLVEQHYPAFKASL
                     EAQGQHLPRYIQQEFNDLLQCGRLEYGFMRVRCEDCHHERLVAFSCKRRGFCPSCGAR
                     RMAESAALLIDEVFPKEPIRQWVLSFPFQLRFLLARHPQLMGQVLSIVYRTLSTHLIK
                     KAGYTKASAQTGSVTLIQRFGSALNLNVHYHMLFLDGVYAEDDYGKQRFHRVKAPTYD
                     ELNTLAHTLSHRIARCMEKRGILERDAENTWLTLEEGEDDTLTQLHGASVTYRIAVGP
                     QQGRKVFTLQTLPGREDKADSSSRVANHAGFSLHAGVMAEAHQRDKLERLCRYISRPA
                     VSEKRLALTANGQVRYELKTPYRNGTTHVIFEPLDFIAKLAALVPKPRVNLTRFHGVF
                     APNSKHRVQVTPAKRGKKPDKSEGLDTNWRDKSPAERHRAMTWMQRLKRVFNIDIEVC
                     EHCGGHVKVIASIEDPKVIEQILKHLKQKTAKANAAKQRELPPERAPPLTPSLFDPSQ
                     SRLFD"
BASE COUNT         1138 a         1559 c         1655 g         1239 t
ORIGIN      
        1 actcatacct agattctacg tcagtacttc aaaaagcata atcaaagcct tgataaatat
       61 gcattccttc gaaattcagc tttcacccat tgggtgaaag aaaagtgctc aacataaaat
      121 actcgaagaa gatttaggca tagatgtata tttctgtgac ccacattcac cctggcaaaa
      181 aggcacatgc gaaaatatga atggtttaat taggcaatat ttacctaaag ggattgattt
      241 aaatcaggca gatcagcatt atttaaatca agttgccatg tcactgaata ctcgtcctag
      301 aaaggcgtta gattggctta caccattaga gaaatttgct cagcttgttg attatcatat
      361 ggcttttgaa actgtcgcac ctcatgtttg aattcgcccc atatttttgc tacagtgaac
      421 caaattaaga tcatctattt actaggcctc gcatttgcgg ggtttttaat gctgaataaa
      481 aggaaaactt gatggaattg cccaatatta tgcacccggt cgcgaagctg agcaccgcat
      541 tagccgctgc attgatgctg agcgggtgca tgcccggtga aatccgcccg acgattggcc
      601 agcaaatgga aactggcgac caacggtttg gcgatctggt tttccgccag ctcgcaccga
      661 atgtctggca gcacacttcc tatctcgaca tgccgggttt cggggcagtc gcttccaacg
      721 gtttgatcgt cagggatggc ggccgcgtgc tgttggtcga taccgcctgg accgatgacc
      781 agaccgccca gatcctcaac tggatcaagc aggagatcaa cctgccggtc gcgctggcgg
      841 tggtgactca cgcgcatcag gacaagatgg gcggtatgga cgcgctgcat gcggcgggga
      901 ttgcgactta tgccaatgcg ttgtcgaacc agcttgcccc gcaagagggg ctggttgcgg
      961 cgcaacacag cctgactttc gccgccaatg gctgggtcga accagcaacc gcgcccaact
     1021 ttggcccgct caaggtattt taccccggcc ccggccacac cagtgacaat atcaccgttg
     1081 ggatcgacgg caccgacatc gcttttggtg gctgcctgat caaggacagc aaggccaagt
     1141 cgctcggcaa tctcggtgat gccgacactg agcactacgc cgcgtcagcg cgcgcgtttg
     1201 gtgcggcgtt ccccaaggcc agcatgatcg tgatgagcca ttccgccccc gatagccgcg
     1261 ccgcaatcac tcatacggcc cgcatggccg acaagctgcg ctgagccatg gctgaccacg
     1321 tcacccccaa tctgccatcg cgcgatttcg atgtgacaga ggcgttttat gcgaagctgg
     1381 gctttgcgac gagttggaag gatcgcggct ggatgatcct gcagcgcggc ggtttgcagc
     1441 tcgaattctt cccctatcct gacctcgacc cagctacgag ctcgttcggc tgttgcctgc
     1501 ggttggatga tctcgatgcc atggtggcat tggtgaacgc ggcgggagcc gaggaaaaaa
     1561 gcaccggctg gccgcgcttc aaagctccgc aactggaggc gagcggcctg aggatcggct
     1621 acctgatcga tcccgactgc acgctggtgc ggctgatcca gaaccccgac tgaccgcatg
     1681 cccgcgaaaa tcaagatttg cgggatcagc acacccgagg cgctcgatgc gaccatcgcg
     1741 gcgcgggcgg actatgccgg gttggtgttc tatccagcgt cgccccgtgc ggttacgtcg
     1801 aatgtcgcgg gcgctttgac atcgcgcgca gctggccaga tcgccatggt cggtttgttc
     1861 gtcgatgcgg atgatgctgt catcgccgac gcactggtgg cagccaagct gaacgcgctg
     1921 cagctgcacg gttcggaatc gcccgaacgc gtggcccagt tgcgcgcgcg gtttggcaag
     1981 ccggtgtgga aggcgctgcc cgtcgccagc gccagcgatg tcgcacgcgc cgcagcctat
     2041 gccggggcgg cggacttgat cttgttcgac gccaagaccc ccaaaggcgc gctgcccggc
     2101 ggcatggggt tggcgttcga ctggtcgctg ctggccggat atcgcggtgc cttgccgtgg
     2161 gggctggcag gcgggctaaa tccgacgaat gttgccgagg cgattgcgcg caccggagcg
     2221 ccgctggtcg atacctccag cggcgtcgaa agcgcgccgg gcgtcaagga taccgacaag
     2281 attaccaatt tcgcctttgc ggtgcgcttg gcctaaatcg cgtcgatcaa taggcgtcgt
     2341 tcagcgcaaa gatcggcttg cgggtgcgcc actgccctcg ggtgaagtcg ggaaaatcta
     2401 acgtgcgatt gccctcagca atcgattgtt ccgacagagg cgtgatcgcg ctccaggcca
     2461 gcgcgtcgta aatgtcgatt ggcatcgggg ccttggcctt cagcgcctcg acaaaagcgt
     2521 ggatcacgaa ccagtccatc ccgccatgcc cggcccctgc cgccagatcg gcgtagcgtt
     2581 tccatagcgg gtgatcgtat ttcgcaaacc agccctcggc aggctcccag cggtgcggct
     2641 gtgggctctt gccctccaga tagatcgact tgttgacgtc catccacagc ccctcggtgc
     2701 cttgcacccg aaagccgaga gaataggggc gcggcagcga ggtgtcgtgg cacagcatga
     2761 tcgtttcacc attagtgcag ccgatcatgg tgttgaccac atcacccagt gcgaatttca
     2821 cctcggcgtt gggatgatcg gcagagccgt tcttgacgac ataatcatgc agcccgcgcg
     2881 ccttacagcc gaagccgcca gcgcccgctt cgcccggcaa cgcgaccttc agggtgcggg
     2941 tctgcggcgg gtagcacacg ccggcatcgg cgcagccctg gtacttcacg gtcagggtgg
     3001 tcgcgctcgc gccggccgcg ggcgtgccgg tgagggtgcc gagcaattcc ttgcggtagg
     3061 tttcgacgtc gccgaagaat tcgtcgcggt aggccttgcc cttcggcagc gccatggtcg
     3121 cgccggtgaa ggcggcatcg gccttgaccg aggtgcggtg ccggtacagg taatagccgt
     3181 cggcgatccg ccagcgcacc tcgatgcggt ccggcgcggt ggcctgcgcg gacaggacga
     3241 agacctcgtc gaccggcggc agttcgaagt cctgggcgac ggccgaggtc gcgggcagcg
     3301 caagcagcag ggcgagcccg gccagccagc ggcgcaggcg gatcgtggat gcggtcattg
     3361 gctcagttta ccggtcggct ctcggcggcc agccattgca ggtattcggg caggccggac
     3421 gcggcttcga ccgcgagcgg gtataggaag tataaaccac ctttttgctc ctcatccgaa
     3481 gtatcttacc tgaaattccc tcactcgttt accgctcaag ccccaatttt aactgccggt
     3541 ccagcctaaa ccgctctaat aaggttcgat ttggcggtaa aatctctagc ctgatagctc
     3601 gagagataca aactgcccca ccgccccgtt taaaagttgg cagtgttgag cagtgttgga
     3661 tttggggtcg tcagtcaaag agacgactct gtgatggatc gaacaggctg ggagtcagtg
     3721 gcggcgctcg ttctggtggc agctcacgct gcttggcggc attcgccttg gctgttttct
     3781 gtttcagatg cttgagaatc tgctcaatga ccttcggatc ttcgatgctg gcaatcactt
     3841 tgacgtgacc gccgcagtgt tcgcagactt caatatcaat attgaagact cgcttgaggc
     3901 gttgcatcca ggtcatggcg cggtggcgct ctgcaggact cttgtcacgc cagttagtat
     3961 cgagaccttc cgatttgtcg ggcttcttgc cccgcttggc gggtgttact tgaactcggt
     4021 gtttgctgtt cggtgcaaag acgccgtgga agcgtgtgag gttgactcgc ggcttaggta
     4081 ccaacgcagc gagtttggcg atgaagtcca gcggctcgaa gatcacatgg gtggtgccat
     4141 tgcggtacgg agttttgagc tcgtaacgca cctgcccatt ggcggttaat gccagacgtt
     4201 tttctgaaac cgctggccga ctaatgtagc gacacaagcg ctcaagctta tcccgctgat
     4261 gcgcttcggc catcacaccg gcgtgtagcg agaaaccagc atggttggct actcgactgc
     4321 ttgagtcggc tttatcctca cgccctggca aggtttgcag ggtgaagact ttgcgccctt
     4381 gctgggggcc gacggcaatg cgatacgtaa ccgaagcacc atgtaattga gtcagcgtat
     4441 cgtcttcgcc ctcttccagt gtcaaccacg tattctcggc atcacgctcc aaaatcccac
     4501 gcttttccat gcagcgagcg atgcgatggc tgagggtgtg agcgagcgta ttcagctcat
     4561 cgtaagtggg tgccttgaca cgatggaagc gttgcttgcc atagtcatct tcggcataga
     4621 caccatcgag aaacagcatg tggtagtgga cattgagatt tagcgcggag ccaaagcgtt
     4681 ggataagagt cactgagcca gtttgtgcag aggctttggt gtaaccggct tttttgatca
     4741 gatgagttga gagtgtacga tagacgatac tcaagacctg gcccatcagc tggggatggc
     4801 gagccagcaa aaagcgtagc tggaaaggaa agctgagcac ccactggcga atgggctcct
     4861 tggggaagac ttcgtctatc agcagcgccg cactctcggc catccggcgg gcaccgcagc
     4921 tagggcaaaa gccgcgtcgt ttacagctga aggcgaccag acgctcgtga tgacaatcct
     4981 cgcagcgaac ccgcatgaaa ccatactcca gacggccaca ttggaggagg tcgttgaatt
     5041 cttgttggat gtagcgaggc aggtgttgac cttgggcttc gagtgaggct ttgaaggctg
     5101 ggtagtgctg ctcaaccagc tggtagagca gcgtctggtc gggttggtgg cgttcgtaac
     5161 cgtttgtttg agtgggcgat tgactcgccg tggcgttcct tgccagcgac atgggtatcc
     5221 tccgctgata ctgtggttat gtacagtatc agcggcttgc gttcagacgt ccagtctggc
     5281 cctagacatc gctaaatgct taacccgcaa tagccctcac gagttgttat cagccactac
     5341 cggttgagcg agaaggtttt gggttcaggg tgctattgct ccaccaatca caatactgaa
     5401 gccccaactg ttatcagttg gggctttttc ttgtctgttt gcggcggttg cgttttatcg
     5461 gtagtcgtcg agctctgcac catcccacat aagagcttaa cggtgcgatc ttcaacgcca
     5521 tcacacaaaa ctttcttttt cacgcacagt caacttattg gatgttttat taacaaccca
     5581 aaaggagata t
//
LOCUS       DAPOAV010000165         5483 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.166, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000165 DAPOAV010000000
VERSION     DAPOAV010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5483
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.166"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(65..445)
                     /gene="crcB"
                     /locus_tag="RN951_004289"
     CDS             complement(65..445)
                     /gene="crcB"
                     /locus_tag="RN951_004289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001318207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HDX2529184.1"
                     /translation="MIKSLFAVIIGGSVGCTLRWLLSTRFNSLFPNLPPGTLVVNLLA
                     GLIIGTALAYFLRQPHLDPFWKLMITTGLCGGLSTFSTFSVEVFALLQAGNYIWALTS
                     VLVHVIGSLIMTALGFFIITILFA"
     gene            complement(786..1199)
                     /locus_tag="RN951_004290"
                     /pseudo
     CDS             complement(786..1199)
                     /locus_tag="RN951_004290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015377870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
     gene            1197..1454
                     /locus_tag="RN951_004291"
                     /pseudo
     CDS             1197..1454
                     /locus_tag="RN951_004291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611787.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            complement(1688..2545)
                     /gene="sitD"
                     /locus_tag="RN951_004292"
     CDS             complement(1688..2545)
                     /gene="sitD"
                     /locus_tag="RN951_004292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter permease subunit
                     SitD"
                     /protein_id="HDX2529185.1"
                     /translation="MMALLLEPLQFTFMSHALLISLVVSIPCALLSVFLVLKSWALMG
                     DAMSHAVFPGIVLAWILGLPLATGAFVAGVFCAVATGYLKDNSRIKQDTVMGIVFSGM
                     FAAGLILYIAVKPDVHLDHILFGDMLGITIGDIIQTVIIAGLVTLVISVKWRDFLLFS
                     FDYQQAQASGLHTRWLHYGLLCMVSLTIVATLKAVGIILSISLLIAPGAIAVLLTQRF
                     HIALLLATGISILVSMTGVWLSFFIDSAPAPTIVVLFAVMFIMTFTVTSINARTKENA
                     EPRDLLSSD"
     gene            complement(2542..3399)
                     /gene="sitC"
                     /locus_tag="RN951_004293"
     CDS             complement(2542..3399)
                     /gene="sitC"
                     /locus_tag="RN951_004293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter permease subunit
                     SitC"
                     /protein_id="HDX2529186.1"
                     /translation="MNVLLEPFSYEYMLNAMWVSAMVGGLCAFLSCYLMLKGWSLIGD
                     ALSHSIVPGVAGAYMLGLPFSLGAFFSGGLAAGSMLFLNQLTRLKEDAIIGLIFSSFF
                     GLGLFMVSLNPTSVNIQTIVLGNILAIDPADILQLTIIGILSIIVLFFKWKDLMVTFF
                     DENHARAIGLHPGRLKILFFTLLSVSTVAALQTVGAFLVICLVVTPGATAWLLTDRFP
                     RLLMIAVTIGSVTSFLGAWVSYFLDGATGGIIVVAQTLLFLLAFVFAPTHGLLANRRR
                     AHKALEDRS"
     gene            complement(3396..4223)
                     /gene="sitB"
                     /locus_tag="RN951_004294"
     CDS             complement(3396..4223)
                     /gene="sitB"
                     /locus_tag="RN951_004294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter ATP-binding
                     protein SitB"
                     /protein_id="HDX2529187.1"
                     /translation="MMQSAGIVVNDVTVTWRNGHTALRDASFTVPGGSIAALVGVNGS
                     GKSTLFKAIMGFVRLTSGKISVLGIPTRQALQKNLVAYVPQSEEVDWSFPVLVEDVVM
                     MGRYGHMGMLRIAKKRDRQIVTDALERVDMVDFRHRQIGELSGGQKKRVFLARAIAQQ
                     GDVILLDEPFTGVDVKTEAKIISLLRELRAEGKTMLVSTHNLGSVTTFCDYTVMVKGT
                     VLASGPTDTTFTAENLELAFSGVLRHVTLNGSEESIITDDERPFVAHRPSAVQREER"
     gene            complement(4223..5137)
                     /gene="sitA"
                     /locus_tag="RN951_004295"
     CDS             complement(4223..5137)
                     /gene="sitA"
                     /locus_tag="RN951_004295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter substrate-binding
                     protein SitA"
                     /protein_id="HDX2529188.1"
                     /translation="MLSIKKVTMLLGCLVLTCSIAFQASAAEKFKVITTFTIIADMAK
                     NVAGDAAEVSSITKPGAEIHEYQPTPGDIKRAQGAQLILANGMNLELWFQRFYQHLNG
                     VPEVIVSSGVTPVGITEGPYEGKPNPHAWMSPDNALIYVDNIRDAFIKYDPINAQTYQ
                     RNADTYKAKITQTLAPLRKQIAELPENQRWMVTSEGAFSYLARDLGLKELYLWPINAD
                     QQGTPQQVRKVVDIVKKNHIPAVFSESTISDKPARQVARETGAHYGGVLYVDSLSTEN
                     GPVPTYIDLLKVTTSTLVQGIKAGKREK"
BASE COUNT         1552 a         1339 c         1263 g         1329 t
ORIGIN      
        1 ccatggagcg aaattctatc ctaagcgtca cattagttga taaacctgta acgttaatga
       61 attctcatgc gaaaagtatg gttatgataa aaaagcctaa agctgtcatg atgagggagc
      121 caatgacgtg aacaagtaca gacgtcaaag cccatatata atttcccgcc tggagtaatg
      181 cgaatacttc aacagaaaat gtagagaaag tactcagacc tccacaaagt cccgttgtta
      241 tcattaattt ccaaaaagga tcaaggtgtg gttgtcgtaa aaagtacgcc aacgcagtac
      301 caataattaa cccggcaagg aggttcacca ccagtgtacc tggaggtaga tttggaaaaa
      361 gactgttaaa gcgtgtggac agtaaccagc gcagagtaca tccaacagaa ccgccgataa
      421 tgacggcaaa aagtgattta atcatgtacc cctcataaaa taatttttta tcgtaacaat
      481 atcagaatat gttctcattt gactgatatt gttaatttat atcctttgac tacatgcaag
      541 ataagggaag gttctattta ttgacattaa taccctcgac aattgctgag cagaagcccc
      601 cacgacaagt gacagaatga caacatctac agtggggagc gttttatcga tgaacaagca
      661 accaagaagt aacacggcat aggtgacgac aatgccagta agcatagaaa taacaaaaac
      721 gtgagctttc atcattcctc cagaataacc ccgacgtgta agcctggggg attggcacaa
      781 taatgtcatt taaaggcaga ctttccggca aattgcgccg atgaacccag ttcatcctca
      841 attctcataa gctggttata tttttcaata cgctcacccc ggcatggagc tcccgttttg
      901 agatgacctg cgcgcattgc aactgtcata tcggcgataa agctgtccac tgtctcacca
      961 ctgcggtgtg agataaaggt gccccagttg ttgtcatggc aaagttgtac cgcatcaaag
     1021 gtttcactca gggaaccaat ctggttgagt ttaatcaatg ctgaattggc aaggttttcg
     1081 tcaatgccgc gctgaatata ctttacgttg gtcacaaaca gatcgtcgcc aaccaattct
     1141 atctgctctc ccaatgcacc atgcaggatt ttccatccag cccagtcatc ttcagctacc
     1201 gttaagggca ggaagatcaa ctaggtgctc tggggctggt gaccaatgcg gttgtgctgt
     1261 gaaacacact ttacatgcag gaggcgttgt cacatcttcg caaatcggga gaaactcctg
     1321 aggagtagca tccggcaaga ttatcgctgc tgatacatag ccatataaat atgctggggc
     1381 attatacgtc ttcgttaccg gaagatattc ttaagggtga gttaagatca ttaaacttca
     1441 atacaaacaa ttaattaaac tcttagcgtg gttttttaca tcactggccc tcgcccccca
     1501 attttctcta tgttttgcca ctacttccct cattttactg cgctgtttgc tacccctgag
     1561 aatcgacatt acttgctatc cagtccgcag caactctctg gcaacaaaac ttatcagaat
     1621 cataagtctg tgcattattc gttcaagcgc atcgccaata agcggatgtt gctggccgag
     1681 tgttctgcta atcggatgat aacaaatccc gtggttcggc attttccttt gtgcgtgcgt
     1741 tgatgctggt aacggtaaac gtcatgatga acatgaccgc gaataagaca acaattgtcg
     1801 gagctggcgc gctgtcgata aaaaaggaca gccagacacc agtcattgag accaatatcg
     1861 atatgccagt cgccagcagg agcgcaatat gaaagcgttg tgtcaggagt accgcaatgg
     1921 caccaggcgc aatgagaaga gaaatagaga gaatgatacc aaccgctttc agcgtcgcca
     1981 caatggtcag ggagaccatg cacagcagcc cataatgcag ccatctcgta tgcaaaccgc
     2041 ttgcctgcgc ctgttgataa tcaaagctga acagcaaaaa atcccgccat tttacgctaa
     2101 taacaagtgt aaccagtccg gcaataatca ccgtctggat tatatcgccg atggttatcc
     2161 cgagcatgtc gccgaaaaga atatgatcaa gatgtacgtc tggtttgact gcaatataca
     2221 agatcagacc tgcggcaaac atgccagaaa aaacaatccc catcactgta tcttgcttga
     2281 ttcggctgtt gtctttcagg tatcccgtcg ccaccgcaca gaatactccg gcgacgaatg
     2341 cccctgtagc cagaggtaac cccagaatcc aggcaagcac gatgccagga aaaaccgcat
     2401 gactcatcgc gtcacccatc agtgcccaac ttttcaggac cagaaagacc gacagcagcg
     2461 cacagggtat ggaaactacc agtgaaatca gcagtgcgtg actcataaag gtgaactgca
     2521 gtggctccag taataatgcc atcatgagcg atcctccagc gctttatgcg cacgccgacg
     2581 atttgccaaa agcccatggg tgggcgcaaa gacaaatgct aaaagaaaca gcagtgtctg
     2641 cgccaccacg atgattccac ctgtcgcgcc gtccagaaag taactgaccc acgcgccgag
     2701 gaaactggtc acactgccaa tagttacagc aatcatgagc aggcggggaa aacgatcggt
     2761 taacaaccat gctgttgcac cgggagtcac caccagacag atcaccagaa aggcaccaac
     2821 cgtttgcagc gccgcaacgg tcgaaaccga cagcagggtg aagaagagga tttttaatct
     2881 gcccggatgc aatccaatag cacgggcgtg attctcgtcg aaaaaggtca ccataagatc
     2941 tttccatttg aaaaaaagca cgatgatcga gagaatgcca atgatagtga gttgcaggat
     3001 atccgccgga tcgattgcca gaatattgcc caggacgatg gtctgaatgt tcacggatgt
     3061 cgggttcaat gacaccataa acagccccag gccaaaaaag gacgagaaga tcaggccgat
     3121 gatggcatct tcttttaagc gagtgagttg gttaagaaac agcatgctgc ccgctgccag
     3181 tccgccggaa aagaaggctc ccagagaaaa cggaagcccc agcatatatg cccccgcaac
     3241 acccgggaca atagagtgcg acagcgcatc gccaatcagc gaccagcctt ttagcatcag
     3301 atagcatgac aggaaagcgc agagaccgcc gaccatcgcc gagacccaca tcgcattgag
     3361 catatattca tagctgaagg gttccagtag cacgttcatc tttcttccct ctgcaccgct
     3421 gacggtcgat gtgccacaaa agggcgttca tcgtcagtaa taatgctttc ttccgagccg
     3481 ttaagtgtga catggcgcag tacgccgcta aaagccagct ccaggttctc ggctgtaaaa
     3541 gtggtgtctg tcggcccgct tgccaggacg gtgcctttga ccatgaccgt ataatcgcaa
     3601 aatgtcgtga cggatccgag attgtgcgtt gagacaagca tcgttttgcc ttccgcgcgt
     3661 aactccctca acaggctgat gattttcgct tcggttttca catcaacgcc ggtaaaaggt
     3721 tcatccagca ggatcacatc accctgctgt gcaatcgctc tcgccagaaa gacgcgtttc
     3781 ttttgtccac cggaaagctc gccgatttgt cgatggcgaa aatccaccat atcgacacgt
     3841 tccagcgcat cggtgacaat ctgacgatcc ctctttttgg cgatacgcaa catacccata
     3901 tgcccatagc ggcccatcat caccacatct tccaccagta caggaaatga ccagtcaacc
     3961 tcttctgact gagggacgta ggcaaccagg tttttctgta gcgcctgtcg tgtgggaata
     4021 cccagaacag atatcttccc gctggtcaga cgcacaaatc ccataatcgc tttaaacaac
     4081 gtcgattttc cggaaccgtt taccccaacc agagcggcaa tagatccgcc tggtactgtg
     4141 aaggatgcat cgcgcagtgc tgtgtgcccg ttacgccagg tgacagtaac atcattaacg
     4201 acaatgcctg cagattgcat cattatttct ccctttttcc ggctttaatt ccctgtacca
     4261 gcgtactggt agtaaccttc agaaggtcga tatacgtagg taccgggccg ttttctgtgc
     4321 tcagggaatc gacatagagc acaccaccgt agtgcgcgcc ggtttcacgc gcaacctgac
     4381 gcgctggttt atcggaaatc gtactctcgc taaagactgc cgggatatga tttttcttaa
     4441 ctatatcaac aaccttacgt acctgctgcg gtgttccttg ttgatcggca ttaatcggcc
     4501 acagataaag ctcttttagc cccaaatcgc gtgcgagata agaaaaagcc ccttcactgg
     4561 tgaccatcca tcgctgattc tcagggagtt ccgcaatctg cttacgcagg ggggcaaggg
     4621 tttgggtaat cttggcttta taagtatcgg cattacgttg gtaggtttgt gcatttatcg
     4681 gatcgtattt tataaacgca tcacgaatat tatcgacgta aatcagagca ttatctggcg
     4741 acatccaggc atgggggtta ggtttgccct catagggccc ttcggtgatc cctactggcg
     4801 tcacacccga agagacaatt acttctggaa ccccattgag atgctggtaa aagcgttgga
     4861 accacaattc cagattcata ccattggcga gaatcagttg tgccccctgc gcacgtttaa
     4921 tatcgccagg ggtaggctga tactcatgaa tttctgcacc aggcttggtt atggatgaga
     4981 cttctgcagc atctccagcc acgtttttgg ccatatctgc gatgatggta aaagttgtaa
     5041 tgaccttgaa tttttcagct gcactcgcct gaaatgctat cgagcaggtg aggactaggc
     5101 accccaagag catggttact ttttttattg agagcatgat ttagtaccta tagtgagcaa
     5161 aattagaata aacatagcaa ctactatgtt ttatagcaga agctataaaa tgtaaataat
     5221 tatcattagc gattataaga tcccaacaca gggattaggt tatttcctgc tgacgatgtg
     5281 gtattgagga taaaagttgg gcagcgcttt ggctttaaaa tgaacttgtt caggacgatt
     5341 ggtaatggca aagcaaaaat aatgtaggtt attggcaagt tctctaggac gcaggagagc
     5401 atgaaaaacc caggggcagt cactaaatga agggatcggt gatgctgcca acttactgat
     5461 ttagtgtatg atggtgtttt tga
//
LOCUS       DAPOAV010000166         5454 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.167, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000166 DAPOAV010000000
VERSION     DAPOAV010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5454
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.167"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            117..338
                     /gene="traR"
                     /locus_tag="RN951_004296"
     CDS             117..338
                     /gene="traR"
                     /locus_tag="RN951_004296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraR"
                     /protein_id="HDX2529189.1"
                     /translation="MSDEADEAYSVTEQLTMTGINRIRQKINAHGIPVYLCEACGNPI
                     PEARRKIFPGVTLCVECQAYQERQRKHYA"
     gene            498..3125
                     /gene="traC"
                     /locus_tag="RN951_004297"
     CDS             498..3125
                     /gene="traC"
                     /locus_tag="RN951_004297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein TraC"
                     /protein_id="HDX2529190.1"
                     /translation="MNNPLEAVTQAVNSLVTALKLPDESAKANEVLGEMSFPQFSRLL
                     PYRDYNQESGLFMNDTTMGFMLEAIPINGANESIVEALDHMLRTKLPRGIPLCIHLMS
                     SQLVGDRIEYGLREFSWSGEQAERFNAITRAYYMKAAATQFPLPEGMNLPLTLRHYRV
                     FISYCSPSKKKSRADILEMENLVKIIRASLQGASITTQTVDAQAFIDIVGEMINHNPD
                     SLYPKRRQLDPYSDLNYQCVEDSFDLKVRADYLTLGLRENGRNSTARILNFHLARNPE
                     IAFLWNVADNYSNLLNPELSISCPFILTLTLVVEDQVKTHSEANLKYMDLEKKSKTSY
                     AKWFPSVEKEAKEWGELRQRLGSGQSSVVSYFLNITAFCKDNNETALEVEQDILNSFR
                     KNGFELISPRFNHMRNFLTCLPFMAGKGLFKQLKEAGVVQRAESFNVANLMPLVADNP
                     LTPAGLLAPTYRNQLAFIDIFFRGMNNTNYNMAVCGTSGAGKTGLIQPLIRSVLDSGG
                     FAVVFDMGDGYKSLCENMGGVYLDGETLRFNPFANITDIDQSAERVRDQLSVMASPNG
                     NLDEVHEGLLLQAVRASWLAKENRARIDDVVDFLKNASDSEQYAESPTIRSRLDEMIV
                     LLDQYTANGTYGQYFNSDEPSLRDDAKMVVLELGGLEDRPSLLVAVMFSLIIYIENRM
                     YRTPRNLKKLNVIDEGWRLLDFKNHKVGEFIEKGYRTARRHTGAYITITQNIVDFDSD
                     KASSAARAAWGNSSYKIILKQSAKEFAKYNQLYPDQFLPLQRDMIGKFGAAKDQWFSS
                     FLLQVENHSSWHRLFVDPLSRAMYSSDGPDFEFVQQKRKEGLSIHEAVWQLAWKKSGP
                     EMASLEAWLEEHEKYRSVA"
     gene            3122..3508
                     /gene="trbI"
                     /locus_tag="RN951_004298"
     CDS             3122..3508
                     /gene="trbI"
                     /locus_tag="RN951_004298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system protein TrbI"
                     /protein_id="HDX2529191.1"
                     /translation="MSSTQKPADVMAERRSHWWWTVPGCLAMVLLNAAVSYGIVRLNA
                     PVTVAFNMKQTVDAFFDRASQKQLSEAQSKALSARFNTALEASLQAWQQKHHAVILVS
                     PAVVQGAPDITREIQQDIARRMRAEP"
     gene            3505..4137
                     /gene="traW"
                     /locus_tag="RN951_004299"
     CDS             3505..4137
                     /gene="traW"
                     /locus_tag="RN951_004299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system protein TraW"
                     /protein_id="HDX2529192.1"
                     /translation="MRCRGLIALLIWGQSVAAADLGTWGDLWPVKEPDMLTVIMQRLT
                     ALEQSGEMGRKMDAFKERVIRNSLRPPAVPGIGRTEKYGSRLFDPSVRLAADIRDNEG
                     RVFARQGEVMNPLQYVPFNQTLYFINGDDPAQVAWMKRQTPPTLESKIILVQGSIPEM
                     QKSLDSRVYFDQNGVLCQRLGIDQVPARVSAVPGDRFLKVEFIPAEEGRK"
     gene            4134..5126
                     /locus_tag="RN951_004300"
     CDS             4134..5126
                     /locus_tag="RN951_004300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer pilus assembly protein TraU"
                     /protein_id="HDX2529193.1"
                     /translation="MKRRLWLLMLFLFAGHVPAASADSACEGRFVNPITDICWSCIFP
                     LSLGSIKVSQGKVPDTANPSMPIQICPALPPLFRRIGLAIGYWEPMALTDVTRSPGCM
                     VNLGFSLPAFGKTAQGTAKKDEKQVNGAFYHVHWYKYPLTYWLNIITSLGCLEGGDLD
                     IAYLSEIDPTWTDSSLTTILNPEAVIFANPIAQGACAADAIASAFNMPLDVLFWCAGS
                     QGSMYPFNGWVSNESSPLQSSLLVSERMAFKLHRQGMIMETIGKNNAVCNEYPSPILP
                     KERWRYQMVNMYPDSGQCHPFGRSVTRWETGKNPPNTKKNFGYLMWRKRNCVFL"
     gene            5135..>5454
                     /locus_tag="RN951_004301"
     CDS             5135..>5454
                     /locus_tag="RN951_004301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001553832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly protein TrbC"
                     /protein_id="HDX2529194.1"
                     /translation="MKLSMKSLAALLMMLNGAVMASENVNTPENRQFLKQQENLSRQL
                     REKPDHQLKAWAEKQVLETPLQRSDNHFLDELVRKQQASQDGKPRQGALYFVSFSIPE
                     EGLKR"
BASE COUNT         1297 a         1389 c         1573 g         1195 t
ORIGIN      
        1 atcagccggc aatgccggcg ggctttctgt attcaaaatc tgcctgtaaa acgagtgccc
       61 tgtgcgtgaa aagggatggg cggtagcgtg tcagaacatg tcgggaggaa tattccgtga
      121 gtgatgaagc cgatgaagca tattcagtga cagaacaact gaccatgaca ggaataaacc
      181 ggatacgcca gaaaataaat gctcatggta ttcctgttta tctctgtgaa gcatgcggaa
      241 atcctattcc ggaagcccgg cggaaaatat ttcccggtgt gacgttgtgc gttgaatgtc
      301 aggcgtatca ggaaagacag agaaaacatt atgcataagt cagtcgcaga acatagtgat
      361 ttaattccgg atgaacatga gtggatattc agaaaacaga aatctttgta tatgcgccgg
      421 gaaatggcgc gttaattaca ggtattccct tcatggctac cgcatttctc gctttatttt
      481 tcaactaagg aattcatgtg aataacccac ttgaggccgt cactcaggcg gttaactccc
      541 tcgtcacagc actgaaactg cctgacgaat ccgcaaaggc caatgaagtt ctgggcgaaa
      601 tgagcttccc gcagttcagc cgtctgctgc cgtaccgtga ttacaaccag gaatccggtc
      661 tgttcatgaa tgacaccacg atgggcttta tgctggaagc catccccatc aatggggcga
      721 atgagtccat tgtggaggcc ctcgatcaca tgctgcgcac caaactgccg cgcggtattc
      781 cgttgtgtat ccatctgatg tccagtcagc tggttggtga caggattgaa tacgggctgc
      841 gtgagttctc ctggtcaggt gaacaggctg aacggtttaa cgccattacc cgggcctatt
      901 atatgaaagc ggcagcgaca cagtttccgc tgccggaggg gatgaatctg cccctgaccc
      961 tgcgccatta ccgggtgttt atctcgtact gttctccttc gaagaaaaaa agccgggccg
     1021 acattctgga aatggaaaac ctggtgaaaa tcatccgggc gtcgttacag ggggccagta
     1081 tcaccacaca gacggtggat gcacaggcct ttatcgatat tgtcggggag atgattaacc
     1141 ataacccgga ctccctgtac ccgaaaagac gtcagctgga cccgtattct gatctgaatt
     1201 atcagtgtgt ggaggacagt tttgatctga aagtccgggc tgattacctg acgctgggcc
     1261 tgcgtgagaa cggcaggaac agcacggccc gcatcctgaa tttccatctg gcccgtaacc
     1321 cggaaatcgc cttcctgtgg aacgtggccg acaactacag caacctgctg aacccggaac
     1381 tgtccatctc ctgtccgttc atcctgacgc tgactctggt ggtggaagac caggtgaaaa
     1441 cccacagcga agccaacctg aagtacatgg acctggagaa aaagtcgaag acctcctatg
     1501 ccaaatggtt tccgtccgtg gagaaagagg cgaaggagtg gggggaactg cgtcagcggc
     1561 tgggctccgg tcagtcctcc gtggtgtcct acttcctcaa catcacagca ttctgcaagg
     1621 acaataatga aacggcgctg gaagtggagc aggacatcct gaacagcttt cgtaaaaacg
     1681 gttttgagct gatttcaccg cgctttaacc acatgcgcaa tttcctgacc tgcctgccct
     1741 ttatggccgg gaaagggctg tttaaacagt tgaaagaggc cggagtggtt cagcgcgcag
     1801 agagctttaa tgttgccaac ctgatgccgt tagtggcgga taaccccctg acaccggcag
     1861 gtctgctggc acccacctac cgtaaccagc tggcgtttat cgatattttc ttccggggga
     1921 tgaataacac caactacaac atggcggtct gtggcacctc cggggccggt aaaaccgggc
     1981 tgatacagcc acttatccgc agcgtgctgg actccggagg ctttgccgtg gtgttcgaca
     2041 tgggggatgg atacaagtcc ctgtgtgaga acatgggcgg ggtgtatctg gacggtgaaa
     2101 ccctgcgttt taacccgttt gcgaacatca ccgatattga ccagtcagcg gagcgtgtcc
     2161 gtgaccagtt gtcagtgatg gccagcccca acggtaacct ggatgaagtg catgaaggtc
     2221 tgctgttgca ggcggtcaga gcctcctggc tggccaaaga gaacagagca cgtattgatg
     2281 acgtggtgga tttcctgaaa aacgccagtg acagcgagca gtatgccgag tcaccgacta
     2341 tccgcagccg tctggacgaa atgattgtgc tgcttgacca gtacactgcc aacggcactt
     2401 acggccagta ttttaactct gatgagccgt ccctgcggga tgacgcaaaa atggtggtgc
     2461 tggagctggg cggactggaa gaccgtccgt cactgctggt tgcggtgatg ttctccctga
     2521 ttatctacat cgagaacagg atgtaccgca cgccgcgtaa cctcaagaaa ctgaacgtta
     2581 ttgatgaagg ctggcgtctg ctggacttca aaaatcacaa ggtcggtgaa tttattgaga
     2641 aaggctaccg tacggcccgc cgtcataccg gtgcctatat caccatcaca cagaacatcg
     2701 tcgactttga ctctgataag gcctccagtg ctgcccgcgc ggcatggggt aactcctcct
     2761 acaaaattat cctcaaacag agtgcgaagg agttcgcgaa atacaaccaa ctgtatccgg
     2821 accagttcct gccactgcag cgcgacatga ttggtaagtt tggtgcggcc aaagaccagt
     2881 ggttcagttc cttcctgctg caggtggaaa accattcctc ctggcaccgt ctgtttgtgg
     2941 acccgttaag ccgcgccatg tacagctctg acggcccgga ttttgagttt gtgcagcaga
     3001 agcgtaaaga ggggctgagt attcatgagg cagtgtggca gctggcgtgg aagaagtcag
     3061 ggccggaaat ggcttcgctg gaagcctggc tggaagaaca tgagaaatac aggagtgtgg
     3121 catgagttca acgcagaaac ccgccgacgt catggcagaa cgacgcagcc actggtggtg
     3181 gacggtgccg ggatgcctgg caatggtgtt actgaacgca gccgtcagtt acggcattgt
     3241 cagactgaac gcaccggtga ctgtcgcctt caacatgaaa cagaccgtgg atgcgttttt
     3301 tgacagagcc agtcagaaac aactgtcaga agcgcagtca aaagcccttt cagcgcgttt
     3361 taacacggca ctggaagcca gcctgcaggc gtggcagcag aaacaccacg cggtcattct
     3421 ggtgtcgcct gctgtggtac agggggcacc ggatatcacc cgggaaatcc agcaggatat
     3481 tgcccggcga atgagggcgg aaccatgaga tgccgggggc tgattgccct gctgatatgg
     3541 gggcagagtg tggccgccgc cgatcttggt acctggggcg atctgtggcc ggtaaaggag
     3601 ccggacatgc tgacggtgat catgcagcgc ctgacggcac tggagcagtc cggtgagatg
     3661 ggccggaaaa tggatgcctt taaggagcgg gtgatccgca acagtctgcg gccccctgcc
     3721 gtgcccggta tcggacgcac ggagaaatac ggcagccggt tgtttgaccc gtccgtcaga
     3781 ctggctgcgg atatccggga taacgaaggg cgggtgtttg cccgtcaggg tgaagtgatg
     3841 aatccgctgc agtatgttcc ttttaaccag acgctgtatt tcatcaatgg cgatgatccg
     3901 gcgcaggtgg cctggatgaa acgccagacg ccgcccacac tggagagcaa aattatcctc
     3961 gtgcagggca gtatcccgga gatgcagaag tctctggaca gccgtgttta ctttgaccag
     4021 aacggtgtgc tctgccagcg cctcggcatt gatcaggtcc cggcacgggt gagcgccgtt
     4081 cccggcgatc gcttcctgaa ggtggaattt attccggcag aggagggcag aaaatgaagc
     4141 gaaggctgtg gctgctgatg ttattccttt tcgccggtca tgtccctgcg gcgtctgcgg
     4201 attctgcctg tgaggggcgt tttgtaaacc cgatcacaga tatctgctgg agctgtattt
     4261 tcccgctctc gctgggcagt atcaaagtca gtcaggggaa ggtccccgac acggcgaacc
     4321 cgtcgatgcc cattcagatt tgtccggcac tgccgccgct gttcaggcgt atcgggctgg
     4381 ccattggtta ctgggagccg atggcgttga cggacgtcac ccggtcaccg ggatgcatgg
     4441 tgaacctggg cttcagcctg ccggcttttg gtaaaacggc acagggaacg gcgaaaaagg
     4501 atgagaagca ggtaaatggg gcgttctatc acgttcactg gtacaaatac ccgctgacgt
     4561 actggctgaa catcatcaca tcgctgggct gtctggaagg tggtgacctg gatatcgctt
     4621 atctttctga aatcgacccc acctggacgg acagcagcct gaccaccatt ctcaatccgg
     4681 aagctgtcat ctttgccaat ccgatagcac agggagcctg cgcagcagat gcgattgcca
     4741 gcgcctttaa tatgcctctc gatgttctgt tctggtgtgc cggttcgcag ggaagtatgt
     4801 acccgttcaa tggctgggtg agtaatgagt ccagtccgtt gcagtcctcc ctgctggtca
     4861 gtgaacgcat ggcgttcaag ctgcaccgtc agggcatgat tatggaaacc atcgggaaaa
     4921 ataacgccgt ctgtaatgaa tatccatccc caatcctgcc caaagaacgc tggcgttacc
     4981 agatggtgaa tatgtacccg gacagcggac agtgccaccc gttcgggcgc agtgtgaccc
     5041 gctgggaaac cgggaaaaat ccgcccaata caaagaaaaa cttcggctac ctgatgtggc
     5101 gtaaacgtaa ctgtgtcttc ctgtgaggtg aatgatgaag ctgagtatga aatctctggc
     5161 agcactgctg atgatgctga acggggcggt tatggcgtca gaaaacgtga acactcctga
     5221 aaaccgccag ttcctgaagc agcaggaaaa tttaagcaga caactgcgtg aaaaacctga
     5281 ccatcagctg aaagcctggg cggagaagca ggtgctggaa accccccttc agcgttcaga
     5341 taaccatttc ctggatgagc tggttcgtaa acagcaggct tcgcaggacg ggaaaccccg
     5401 gcagggtgcc ctgtattttg tgtcgttttc cattcccgaa gaggggctga aacg
//
LOCUS       DAPOAV010000167         5440 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.168, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000167 DAPOAV010000000
VERSION     DAPOAV010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5440
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.168"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            18..140
                     /locus_tag="RN951_004302"
     CDS             18..140
                     /locus_tag="RN951_004302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small membrane protein"
                     /protein_id="HDX2529195.1"
                     /translation="MENLFSLVVAAILLAVSVFFLISYLKDRKKTKLTFNKRKW"
     gene            complement(563..1729)
                     /gene="ugd"
                     /locus_tag="RN951_004303"
     CDS             complement(563..1729)
                     /gene="ugd"
                     /locus_tag="RN951_004303"
                     /EC_number="1.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HDX2529196.1"
                     /translation="MKITISGTGYVGLSNGVLIAQNHEVVALDIVQAKVDMLNQKISP
                     IVDKEIQEYLAEKPLNFRATTDKHDAYRNADYVIIATPTDYDPKTNYFNTSTVEAVIR
                     DVTEINPNAVMIIKSTIPVGFTRDIKERLGIDNVIFSPEFLREGRALYDNLHPSRIVI
                     GERSARAERFADLLKEGAIKQDIPTLFTDSTEAEAIKLFANTYLALRVAYFNELDSYA
                     ESQGLNSKQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYESVPNNIIAAI
                     VDANRTRKDFIADSILARKPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKAKGIPVII
                     YEPVMQEDEFFNSRVVRDLDAFKQEADVIISNRMAEELADVADKVYTRDLFGND"
     gene            complement(1910..2464)
                     /gene="rfbC"
                     /locus_tag="RN951_004304"
     CDS             complement(1910..2464)
                     /gene="rfbC"
                     /locus_tag="RN951_004304"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HDX2529197.1"
                     /translation="MNIIKTDIPEVLIFEPRVFGDARGFFFESFSSKVFNEAVGRQVD
                     FVQDNHSQSQKGVLRGLHYQLAPHAQGKLVRCVEGEVFDVAVDIRRSSPTFGKWVGAV
                     LSAENKRQLWIPEGFAHGFMALSDTVQFVYKATNYYAPQSERSIIWNDPEIGIDWPAL
                     SDCALSLSEKDLQAHTLATAEVYK"
     gene            complement(2479..3369)
                     /gene="rfbD"
                     /locus_tag="RN951_004305"
     CDS             complement(2479..3369)
                     /gene="rfbD"
                     /locus_tag="RN951_004305"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HDX2529198.1"
                     /translation="MKILLIGKNGQVGWELQRSLSTLGDVVAVDYFDKELCGDLTNLE
                     GIAQTVRTVRPDVVVNAAAHTAVDKAESERELSDLLNDKGVAVLAAESAKLGALMVHY
                     STDYVFDGAGSHYRREDEATGPLNVYGETKRAGELALEQGNPRHLIFRTSWVYATRGA
                     NFAKTMLRLAGEKETLSIIDDQHGAPTGAELLADCTATAIRETLRNPALAGTYHLVAS
                     GETSWCDYARYVFEVARAHGAELAVQEVKGIPTTAYPTPAKRPLNSRLSNEKFQQAFG
                     VTLPDWRQGVARVVTEVLGK"
     gene            complement(3401..4270)
                     /gene="rfbA"
                     /locus_tag="RN951_004306"
     CDS             complement(3401..4270)
                     /gene="rfbA"
                     /locus_tag="RN951_004306"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016161475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HDX2529199.1"
                     /translation="MKGIVLAGGSGTRLYPITQGVSKQLLPIYDKPMIFYPVSVLMLA
                     GIRDILIISTPDDMPSFQRLLGDGAQFGVNFSYAIQPSPDGLAQAFIIGEKFIGNDAC
                     ALVLGDNIYFGQSFGKKLEAAAAKTSGATVFGYQVLDPERFGVVEFDENFKALSIEEK
                     PLKPKSDWAVTGLYFYDNNVVEMAKDVKPSERGELEITTLNQMYLEQGDLHVELLGRG
                     FAWLDTGTHDSLVDASQFIHTIEKRQGMKVACLEEIAYRNQWLSAEGVAAQAERLKKT
                     EYGAYLKRLLNER"
     gene            complement(4297..5361)
                     /gene="rfbB"
                     /locus_tag="RN951_004307"
     CDS             complement(4297..5361)
                     /gene="rfbB"
                     /locus_tag="RN951_004307"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HDX2529200.1"
                     /translation="MKILVTGGAGFIGSAVVRHIIENTRDEVRVVDCLTYAGNLESLA
                     PVAGSERYSFSQTDITDAAAVAAQFSEFRPDIVMHLAAESHVDRSIDGPTAFIQTNVI
                     GTFTLLEAARHYWSGLGEEQKQAFRFHHISTDEVYGDLHGTDDLFTEETPYAPSSPYS
                     ASKAGSDHLVRAWNRTYGLPVVVTNCSNNYGPYHFPEKLIPLTILNALAGKPLPVYGN
                     GEQIRDWLYVEDHARALYKVATEGKSGETYNIGGHNERKNIDVVRTICAILDKVVAQK
                     PGNITHFADLITFVTDRPGHDLRYAIDAAKIQRDLGWVPQETFESGIEKTVHWYLNNQ
                     TWWQRVLDGSYAGERLGLNN"
BASE COUNT         1234 a         1532 c         1408 g         1266 t
ORIGIN      
        1 aagctgtggt agatattatg gaaaacctgt tttccttagt ggtggctgcc atactacttg
       61 ctgtgtcggt tttcttttta atttcatatc tgaaagacag aaagaaaacc aaactgacgt
      121 ttaataaacg caagtggtaa ggcccactcc atattgcaat tagattaaga aaatattaag
      181 agataaaaaa atgatatgac agaatgaccg ttcattctgc gttttggcgt ggccttaagg
      241 caagaaaaaa taacgttact cacgccctgt tcctcatatt tccccagggc ataaataaca
      301 aaagcctgcg ttgcaggctt tgttttacct cccggcgctt atctccggca tctacatcac
      361 agtgacggta gctcttcaca aggtaagttt aacttatcgg acctgttttc aacctacaac
      421 ggcttttaag cagggtcgta atgtccatca caatttattg aggttaatct gaatgtgcga
      481 gaaatacgcg cagtgaggaa tatagcgggg agataaagaa gcatactggc ggcgaggagc
      541 cgccagtgtc agacaggcag gattaatcgt taccaaacag atcgcgggtg tataccttgt
      601 ccgccacatc cgccagctct tccgccatac ggttagagat aatcacatcc gcctcttgtt
      661 tgaaggcatc caggtcgcgc actacgcggg agttaaagaa ctcatcttcc tgcatcaccg
      721 gttcatagat aataaccgga ataccttttg ccttgatgcg cttcataatg ccctgaatag
      781 aagaggcacg gaagttgtcc gaaccactct tcatgatcag gcgatacaca cccaccactt
      841 tcggcttacg ggcaagaata gaatccgcga taaagtcttt acgggtacgg ttagcatcta
      901 cgatagccgc gatgatattg ttcgggaccg attcgtagtt cgccagcaac tgcttggtat
      961 ctttcggcag gcagtagccg ccatagccaa aggacgggtt gttatagtgg ttgccgatac
     1021 gcggatccag gcatacccct tcgataatct gcttgctgtt cagcccctgg ctttcagcat
     1081 agctgtcaag ctcgttgaaa taggcaacgc gcagcgccag ataggtgttc gcgaacagtt
     1141 tgatcgcttc cgcttcagtg gagtcggtaa acagggtcgg gatatcctgc ttaatcgcgc
     1201 cttctttcaa caggtctgcg aaacgttcgg cacgtgcaga gcgctcacca atgacaatgc
     1261 gcgacgggtg caggttatcg tacagcgcac ggccttcacg caggaactca ggagagaaaa
     1321 taacattatc aatccctaaa cgttctttga tgtcgcgggt gaaccccacc gggatggtcg
     1381 atttaatgat catcaccgcg ttcgggttga tctctgtgac atcgcgaata accgcttcca
     1441 ccgtagaggt gttgaagtag ttagtcttgg gatcgtaatc ggtcggcgtg gcaatgatca
     1501 cgtagtcggc attgcggtac gcgtcgtgct tatccgtggt ggcacggaaa tttaacggtt
     1561 tttctgccag atattcctga atctctttat ccacaatcgg agagatcttc tggttaagca
     1621 tatccacttt ggcctgtacg atatccagag caaccacttc gtggttttgc gcaatcagga
     1681 caccgttcga taaaccaaca taacctgtac cggaaatagt aattttcatt cgattacact
     1741 ttaatcagtt aactgggtaa tggcggatag ccacgaattt aaataatgct gttggcggtt
     1801 ttacgctgag aaggaaggta agtcaagtcg gtcggttgac ccggcttgtt aacgaagaaa
     1861 catgacgagt tccatctgga acccgccatt ttaggaaaaa acaacctaat tatttatata
     1921 cttctgcagt ggcaagagta tgtgcctgca gatctttctc cgacagcgag agcgcgcaat
     1981 cgctcagcgc cggccagtca atcccgatct ccggatcgtt ccagatgatg ctccgttctg
     2041 actgcggcgc gtagtagttc gtcgccttgt agacaaactg caccgtgtcg ctcagcgcca
     2101 taaacccgtg ggcgaaccct tccgggatcc acagctgacg tttattctct gcgctgagta
     2161 ccgcgcccac ccatttgcca aaggtgggcg atgaacgacg gatatccacc gccacatcaa
     2221 acacctcacc ttccacacag cggaccagtt tgccctgggc gtgcggagcc agctgatagt
     2281 gcagcccgcg cagtacgcct ttctgggact gggagtggtt gtcctgaaca aaatctacct
     2341 ggcggcccac cgcttcatta aacaccttgc tgctgaagct ctcgaagaag aagccccgcg
     2401 catcaccaaa cacgcgcggt tcaaaaatca gcacctcagg aatatctgtt ttaataatgt
     2461 tcatcgtttg ccacccgttt atttgcccag gacttctgtt accacgcgag ccacaccctg
     2521 acgccagtcc gggagagtca ccccaaatgc ctgctggaat ttttcattcg acaggcgtga
     2581 gttgagcgga cgcttcgccg gcgtcggata ggccgtcgtc ggaatgccct tcacttcctg
     2641 aaccgccagc tctgcaccgt gcgccctcgc cacctcaaac acatagcggg cgtagtcgca
     2701 ccagctggtc tcgccgctgg ccaccagatg ataggtaccg gccagcgccg gattacgcaa
     2761 cgtttcacgg attgccgtcg ccgtgcagtc tgccagcagc tcagcgccgg tgggcgcccc
     2821 gtgctggtcg tcaatgatgg agagcgtctc tttctcaccc gccaggcgga gcatggtttt
     2881 ggcaaagttg gcgccgcggg tggcatacac ccagctggta cggaaaatca ggtgacgcgg
     2941 gttaccctgc tccagggcca gttcaccggc gcgtttggtt tcgccgtaga cgttcagcgg
     3001 gccggttgcc tcatcttccc ggcgataatg gctgccggcg ccgtcgaaca cataatccgt
     3061 ggaatagtgc accatcaggg cacccagctt cgccgactct gccgctagca ccgccacccc
     3121 tttgtcgttc agcaggtcgg agagctcccg ctcgctttct gccttgtcca ccgccgtgtg
     3181 cgcggcggca ttcaccacca catccgggcg gacggtacgc acggtctgcg cgatgccttc
     3241 cagattagtc aggtcgccgc acagctcttt gtcaaagtag tccaccgcga ccacgtcgcc
     3301 gagggtggac agtgaacgct gcagttccca gcccacctgg ccattcttgc caatcagtaa
     3361 aatcttcatt ctctgtatcc tgtcgttgac gaagaaggca ttaacgctcg ttcagcaggc
     3421 gcttcagata agcaccgtac tcggttttct tcaggcgttc cgcctgagcc gccacccctt
     3481 ccgccgacag ccactgatta cggtaggcta tctcttccag gcaggccact ttcatcccct
     3541 ggcgcttctc aatggtgtga atgaactgcg acgcgtccac caggctgtcg tgggtgcccg
     3601 tatccagcca agcaaaaccg cgccccagca gttcaacatg caggtcacct tgctccagat
     3661 acatctggtt cagggtggtg atctccagct cgccgcgttc agaaggcttc acgtccttcg
     3721 ccatctccac cacgttattg tcgtagaaat agagcccggt caccgcccag tctgatttcg
     3781 gcttcagcgg tttctcctcg atagacagtg ccttaaagtt ctcatcgaac tccaccaccc
     3841 cgaagcgctc cggatccagc acctgataac caaacaccgt ggcaccggaa gtcttcgccg
     3901 ctgccgcttc cagcttttta ccgaagctct ggccaaagta gatattatct cccagcacca
     3961 gggcgcaggc atcgttgccg atgaacttct cgccaatgat aaaggcctgc gccaggccgt
     4021 ccggcgacgg ctggatggcg taactgaagt tcaccccgaa ctgcgccccg tcacccagca
     4081 ggcgctggaa ggaaggcatg tcgtccgggg tggagataat caggatgtcg cgaatccccg
     4141 ccagcatcag gacggacacc gggtagaaaa tcatcggctt gtcatagatc ggcagcagct
     4201 gcttggagac gccctgggtg atcggatata aacgcgtgcc ggagccgccg gccagaacaa
     4261 tacctttcat aaatctattc cttaatcagt cagatatcag ttatttaggc ccagacgctc
     4321 accggcatag gagccatcca gcacgcgctg ccaccaggtc tggttgttaa gataccagtg
     4381 cacggttttt tcaatcccgc tctcgaacgt ctcctgcggc acccagccca gatcgcgctg
     4441 aatttttgcg gcatcaatgg cgtagcgcag gtcgtgtccc ggacggtcgg tgacaaaagt
     4501 gatcaggtct gcgaaatgag tgatgttacc cggcttctgc gccaccacct tgtcgagaat
     4561 ggcgcagatg gtgcgcacca catcgatatt tttacgctcg ttatgaccgc caatattgta
     4621 ggtttcgccg ctcttgcctt cggtcgccac tttatacagc gcacgggcat ggtcctcaac
     4681 atacagccag tcacggatct gctccccgtt gccatacacc ggcagcggtt tacccgccag
     4741 ggcgttgagg atagtcagcg ggattagttt ctccgggaag tgatacggac catagttgtt
     4801 ggagcagttg gtcaccacca ccggcaggcc gtaggtgcgg ttccaggcgc gaaccagatg
     4861 gtcgctgccc gctttggagg cggagtacgg gctactcggc gcgtacgggg tttcttcggt
     4921 gaacaggtca tcggtgccat gcaggtctcc atacacttca tcggtggaga tgtggtggaa
     4981 gcggaaagcc tgcttctgct cctccccaag cccggaccag tagtgacggg ccgcttccag
     5041 cagagtgaag gtgccgatca cgttggtttg gatgaaggcg gtcgggccat caatggagcg
     5101 atccacatga ctttctgccg ccaggtgcat cacgatatcc gggcggaact cactgaactg
     5161 ggccgccacg gcagcggcat ccgtgatatc agtctgggaa aacgagtagc gttcgctccc
     5221 ggccaccggc gccagggatt cgaggttgcc ggcgtaggtc aggcagtcca ccacgcggac
     5281 ttcatcccgg gtattttcaa tgatatgacg aactacggca gagccgataa agcctgcgcc
     5341 accggtgaca agaatcttca tattttattt acctttgatt actgatgcaa aaagaaaata
     5401 agtgcataca tctccagatt aaaatgtttg agatgtaatt
//
LOCUS       DAPOAV010000168         5440 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.169, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000168 DAPOAV010000000
VERSION     DAPOAV010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5440
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.169"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            122..1456
                     /gene="garP"
                     /locus_tag="RN951_004308"
     CDS             122..1456
                     /gene="garP"
                     /locus_tag="RN951_004308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate/glucarate/glycerate transporter
                     GarP"
                     /protein_id="HDX2529201.1"
                     /translation="MILDTVDEKKKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEV
                     AKELQLSAVSMGYIFSAFGWAYLLMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGF
                     VDMFPLAWAGISMFFMRFMLGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFS
                     LALFSPLLGWLTFAWGWEHVFTVMGVIGFVLTALWIKLIHNPTDHPRMSAEELKFISE
                     NGAVVDMDHKKPGSAAASGPKLHYIKQLLSNRMMLGVFFGQYFINTITWFFLTWFPIY
                     LVQEKGMSILKVGLVASIPALCGFAGGVLGGVFSDYLIKRGLSLTLARKLPIVLGMLL
                     ASTIILCNYTNNTTLVVMLMALAFFGKGFGALGWPVISDTAPKEIVGLCGGVFNVFGN
                     VASIVTPLVIGYLVSELHSFNAALVFVGCSALMAMVCYLFVVGDIKRMELQK"
     gene            1472..2242
                     /gene="garL"
                     /locus_tag="RN951_004309"
     CDS             1472..2242
                     /gene="garL"
                     /locus_tag="RN951_004309"
                     /EC_number="4.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxyglucarate aldolase"
                     /protein_id="HDX2529202.1"
                     /translation="MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWL
                     VLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVET
                     KEEAELAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDN
                     VDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAP
                     VEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK"
     gene            2272..3162
                     /gene="garR"
                     /locus_tag="RN951_004310"
     CDS             2272..3162
                     /gene="garR"
                     /locus_tag="RN951_004310"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HDX2529203.1"
                     /translation="MTMKVGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAA
                     GAETASTAKAIAEQCDVIITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLA
                     SREISEALKAKGIDMLDAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVV
                     HTGEIGAGNVTKLANQVIVALNIAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLD
                     AKAPMVMDRNFKPGFRIDLHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGLGT
                     ADHSALACYYEKLAKVEVTR"
     gene            3259..4404
                     /gene="garK"
                     /locus_tag="RN951_004311"
     CDS             3259..4404
                     /gene="garK"
                     /locus_tag="RN951_004311"
                     /EC_number="2.7.1.165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417593.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 2-kinase"
                     /protein_id="HDX2529204.1"
                     /translation="MKIVIAPDSYKESLSASEVAQAIEKGFREIFPDAQYVSVPVADG
                     GEGTVEAMIAATQGAERHAWVTGPLGEKVNASWGISGDGKTAFIEMAAASGLELVPAE
                     KRDPLVTTSRGTGELILQALESGATNIIIGIGGSATNDGGAGMVQALGAKLCDANGNE
                     IGFGGGSLNTLNDIDISGLDPRLKDCVIRVACDVTNPLVGDNGASRIFGPQKGASEAM
                     IVELDNNLSHYAEVIKKALHVDVKDVPGAGAAGGMGAALMAFLGAELKSGIEIVTTAL
                     NLEEHIHDCTLVITGEGRIDSQSIHGKVPIGVANVAKKYHKPVIGIAGSLTDDVGVVH
                     QHGIDAVFSVLTSIGTLDEAFRGAYDNICRASRNIAATLAIGMRNAG"
     gene            4437..4813
                     /gene="rnpB"
                     /locus_tag="RN951_004312"
     ncRNA           4437..4813
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="RN951_004312"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
BASE COUNT         1291 a         1295 c         1539 g         1315 t
ORIGIN      
        1 attattctcg cgctgcttat actaattccc gagttcattg tcgttacggc ataaatgaaa
       61 ctcataaata acaccttccc cataataata aaaatcagca taagtacccg aggtaaataa
      121 aatgattctg gacaccgttg acgaaaaaaa gaaaggcgtg catacccgct atttaatatt
      181 actgattatt tttattgtta ccgccgttaa ctacgccgat cgtgcaacgc tgtctattgc
      241 tggtaccgaa gtggcaaaag agttgcagtt aagtgcggtt tcgatgggtt acatcttctc
      301 cgcttttggc tgggcctact tgctgatgca aatccccggc ggctggctgc ttgataagtt
      361 tggctcgaaa aaagtttaca cctacagcct ctttttctgg tcgctattca ccttcctgca
      421 aggctttgtt gatatgttcc cgctggcctg ggcagggatc tccatgttct ttatgcgctt
      481 tatgctcggc ttctcggaag cgccatcatt cccggcgaac gcccgaattg tcgccgcctg
      541 gttcccgacg aaagaacgtg gtactgcctc cgccatcttt aactcggcgc aatatttctc
      601 gctggcgctc ttttcgccgc tgcttggctg gctgactttc gcctggggct gggagcacgt
      661 ctttaccgtt atgggggtga ttggttttgt gctgacggcg ctgtggatca agttgattca
      721 taacccgaca gatcacccac gtatgtctgc ggaagagctg aagtttatct ctgaaaatgg
      781 cgcggtggtc gatatggacc acaaaaagcc gggcagtgcg gcagcaagcg gacccaaact
      841 gcattacatc aagcaattgc tctctaaccg catgatgctg ggcgtatttt tcggacaata
      901 ttttatcaac accatcacct ggttcttcct cacctggttc ccgatttatc tggtgcagga
      961 aaaaggcatg tcgattctga aagtgggtct ggtcgcctcg attccagcac tgtgtggttt
     1021 tgcgggcggc gtgctgggag gtgtcttctc ggattatctg atcaaacgcg gtttatccct
     1081 gaccctggca cgtaagctac cgattgtgct gggaatgttg ctggcttcca ccatcatctt
     1141 atgtaactac accaacaaca ccacgctggt ggtcatgctg atggcgctgg ctttctttgg
     1201 caaaggattt ggtgcgctgg gctggccggt gatttctgac accgcgccga aagagattgt
     1261 tggcctctgc ggcggcgtct ttaacgtctt tggcaatgtt gcctccattg tcactccact
     1321 ggtgattggc tacctggtaa gtgaactgca ctccttcaat gcagcactgg ttttcgtggg
     1381 atgttcagcg ctgatggcga tggtctgcta cctcttcgta gttggcgaca ttaaacgtat
     1441 ggaattgcag aaataagcaa aggtataagc gatgaataac gatgttttcc cgaataaatt
     1501 caaagccgca ctggctgcga aacaggtaca aattggttgc tggtcagcac tctctaaccc
     1561 gattagcact gaagttcttg gtttggctgg gtttgactgg ctggtgctgg atggcgaaca
     1621 tgcgccaaac gatatctcca cgtttattcc gcagttaatg gccttgaaag gcagcgccag
     1681 cgcgccagta gtgcgagtgc cgaccaacga gccggtaatt attaagcgtc ttctggatat
     1741 cggtttctat aacttcctga ttccttttgt agaaacaaaa gaggaagcag agctggcggt
     1801 ggcatcaacc cgttacccac cggaaggcat tcgcggcgtc tccgtttctc accgcgccaa
     1861 tatgtttggc accgtggcgg attatttcgc tcagtcgaac aagaacatca ctattctggt
     1921 ccagatagaa agtcagcagg gcgtagataa cgtcgatgcc attgccgcta ccgaaggcgt
     1981 agacggcatc ttcgtcggcc ccagcgatct ggccgcggca ttaggccatc tcggcaatgc
     2041 atcacacccg gatgtacaaa aagcaattca gcacattttt aaccgtgcca gcgcgcacgg
     2101 caaacccagc ggtatcctcg cgccggtcga agccgatgcg cgtcgttatc tggaatgggg
     2161 cgcgacgttt gtggctgtcg gcagcgatct cggcgtcttc cgctctgcca ctcagaaact
     2221 ggctgatacc tttaaaaaat aaccaccacc gcaacaagag agatgattga tatgactatg
     2281 aaagttggtt ttattggcct ggggattatg ggtaaaccaa tgagtaaaaa ccttctgaaa
     2341 gcaggttact cgctggtggt tgctgaccgt aacccagaag ctattgctga cgtgattgct
     2401 gcaggtgcag aaacagcgtc tacggctaaa gcgatcgctg aacagtgcga cgtcatcata
     2461 accatgctgc caaactcccc tcatgtgaaa gaggtggcgc tgggtgagaa tggcattatt
     2521 gaaggcgcga agccaggtac ggtattgatc gatatgagtt ctatcgcacc gctggcaagc
     2581 cgtgaaatca gcgaagcgct gaaagcgaaa ggcattgata tgctggatgc tccggtgagc
     2641 ggcggtgaac cgaaagccat cgacggtacg ctgtcagtga tggtgggcgg cgacaaggct
     2701 attttcgaca aatactatga tttgatgaaa gcgatggcgg gttccgtggt gcataccggg
     2761 gaaatcggtg caggtaacgt caccaaactg gcaaatcagg tcattgtggc gctgaatatt
     2821 gccgcgatgt cagaagcgtt aacgctggca actaaagcgg gcgttaaccc ggacctggtt
     2881 tatcaggcaa ttcgcggtgg actggcgggc agtaccgtgc tggatgccaa agcgccgatg
     2941 gtgatggacc gcaacttcaa gccgggcttc cgtattgatc tgcatattaa ggatctggcg
     3001 aatgcgctgg atacttctca cggcgtcggc gcacaactgc cgctcacagc tgcggttatg
     3061 gagatgatgc aggcactgcg agcagatggt ttaggaacgg cggatcatag cgccctggcg
     3121 tgctactacg aaaaactggc gaaagtcgaa gttactcgtt aatgacgtcg tgcccggatg
     3181 gcgtattgca atccgggcct ggaatccagg ccgaataaga gaaacgccct ccggcgtcat
     3241 gtggtaacag gcataggtat gaaaatcgta atcgccccag actcttataa agaaagttta
     3301 tctgccagcg aggttgcgca ggcgatagaa aaaggatttc gggaaatttt tcctgatgca
     3361 cagtacgttt ctgttccggt tgccgacggt ggcgaaggaa cggtggaagc gatgattgca
     3421 gccacccagg gggctgaacg tcacgcctgg gttacagggc cgctgggcga gaaagtgaat
     3481 gccagttggg ggatctccgg cgatggcaaa accgcgttta ttgaaatggc ggcggccagt
     3541 gggctggagc tggtacctgc ggaaaaacgc gatccactcg tgaccacttc acgcggcaca
     3601 ggcgagttaa tcctgcaggc gctggagagc ggtgcgacaa acattattat cggcattggc
     3661 ggcagcgcta caaatgatgg cggcgcaggc atggtacagg cgctgggggc gaaattatgc
     3721 gacgccaacg gcaatgaaat tggttttggc ggcggtagtc ttaatactct gaatgatatt
     3781 gatatttccg gcctcgatcc gcgcttaaaa gattgcgtca ttcgcgtcgc ttgtgatgtc
     3841 accaatccgc tggtgggcga taacggcgca tcgcgcatct ttggcccaca aaagggagcc
     3901 agtgaagcga tgattgttga gctggacaat aacctctctc actatgccga ggtcattaaa
     3961 aaagcgctgc atgttgatgt gaaagatgtc cccggtgcag gagctgcggg tggtatgggc
     4021 gcggcgctaa tggcgtttct tggtgcggaa ctgaaaagtg gtattgaaat cgtcactacg
     4081 gcgctgaatc tggaggaaca tattcacgat tgtacgctgg tgatcaccgg tgaagggcgt
     4141 attgacagcc agagtattca cgggaaggta ccgattggtg tcgcaaacgt ggcgaagaag
     4201 taccataaac cggtgattgg cattgcgggt agcctgaccg atgatgttgg cgttgtacat
     4261 cagcatggca ttgatgcggt cttcagcgta ttgaccagca taggtacgtt ggacgaagca
     4321 ttccgcgggg cttatgacaa tatctgccgt gcttcacgta atatcgccgc gacactggcg
     4381 attggaatgc gcaacgcggg gtgacaaggg cgcgcaaacc ctctatactg cgcgccgaag
     4441 ctgaccagac agtcgccgct tcgtcgtcgt cctcttcggg ggagacgggc ggaggggagg
     4501 aaagtccggg ctccataggg cagggtgcca ggtaacgcct gggggggaaa cccacgacca
     4561 gtgcaacaga gagcaaaccg ccgatggccc gcgcaagcgg gatcaggtaa gggtgaaagg
     4621 gtgcggtaag agcgcaccgc gcggctggta acagtccgtg gcacggtaaa ctccacccgg
     4681 agcaaggcca aataggggtt cataaggtac ggcccgtact gaacccgggt aggctgcttg
     4741 agccagtgag cgattgctgg cctagatgaa tgactgtcca cgacagaacc cggcttatcg
     4801 gtcagtttca cctgatttac gtaaaaaccc gcttcggcgg gtttttgctt ttggaggggc
     4861 agaaagatga atgactgtcc acgacgctat acccaaaaga aagcggctta tcggtcagtt
     4921 tcacctggtt tacgtaaaaa cccgcttcgg cgggtttttg cttttggagg ggcagaaaga
     4981 tgaatgactg tccacgacac tatacccaaa agaaagcggc ttatcggtca gtttcacctg
     5041 ttttacgtaa aaacccgctt cggcgggttt ttacttttgg aggggcagaa agatgaatga
     5101 ctgtccacga cactataccc aaaagaaagc ggcttatcgg tcagttttac ctgatgtacg
     5161 taataaaccg ttccggcggg tttcagattg ttgagtgcgc tttattcatg ccggatgcgg
     5221 cgtgaacgcc ttatcctgcc tacaaaagca cgcaaattca atatattgca gagatggcgt
     5281 aggcctgata agcgtagcgc atcaggcatt tttgcggttg ccatcagttt caaacccgcg
     5341 tcagtgagtt tttgcttttg gtgcacaggg taagatgaat aaatatctac ggtattaata
     5401 atagactttg taagaagtta ttaagtctat attgcattta
//
LOCUS       DAPOAV010000169         5436 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.170, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000169 DAPOAV010000000
VERSION     DAPOAV010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5436
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.170"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..841)
                     /gene="yeaE"
                     /locus_tag="RN951_004313"
     CDS             complement(<1..841)
                     /gene="yeaE"
                     /locus_tag="RN951_004313"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal reductase YeaE"
                     /protein_id="HDX2529205.1"
                     /translation="MQQKMIQFSGDVSLPAVGQGTWYMGEDASQRKTEVAALRAGIEL
                     GLTLIDTAEMYADGGAEKVVGEALTGLREKVFLVSKVYPWNAGGQKAINACEASLRRL
                     NTDYLDLYLLHWSGSFAFEETVAAMEKLIAQGKIRRWGVSNLDYADMQELWQLPGGNQ
                     CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHA
                     HNISAAQVLLAWVISHQGVMAIPKAATIAHVQQNAAVLEVELSSAELAMLDKAYPAPK
                     GKTA"
     gene            complement(931..1677)
                     /gene="mipA"
                     /locus_tag="RN951_004314"
     CDS             complement(931..1677)
                     /gene="mipA"
                     /locus_tag="RN951_004314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="scaffolding protein MipA"
                     /protein_id="HDX2529206.1"
                     /translation="MTKLKLLALGVLIATSAGVAHAEGKFSLGAGVGVVEHPYKDYDT
                     DVYPVPVINYEGDNFWFRGLGGGYYLWNDATDKLSITAYWSPLYFKAKDSGDHQMRHL
                     DDRKSTMMAGLSYAHFTQYGYLRTTLAGDTLDNSNGIVWDMAWLYRYTNGGLTVTPGI
                     GVQWNSENQNEYYYGVSRKESARSGLRGYNPNDSWSPYLELSASYNFLGDWSVYGTAR
                     YTRLSDEVTDSPMVDKSWTGLISTGITYKF"
     gene            2113..4047
                     /gene="yeaG"
                     /locus_tag="RN951_004315"
     CDS             2113..4047
                     /gene="yeaG"
                     /locus_tag="RN951_004315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase YeaG"
                     /protein_id="HDX2529207.1"
                     /translation="MNIFDHYRQRYEAAKDEEFTLQEFLTTCRQDRSAYANAAERLLM
                     AIGEPVMVDTAQEPRLSRLFSNRVIARYPAFEEFYGMEDAIEQIVSYLKHAAQGLEEK
                     KQILYLLGPVGGGKSSLAERLKSLMQLVPIYVLSANGERSPVNDHPFCLFNPQEDAQI
                     LEKEYGIPRRYLGTIMSPWAAKRLHEFGGDITKFRVVKVWPSILQQIAIAKTEPGDEN
                     NQDISALVGKVDIRKLEHYAQNDPDAYGYSGALCRANQGIMEFVEMFKAPIKVLHPLL
                     TATQEGNYNGTEGISALPFNGIILAHSNESEWVTFRNNKNNEAFLDRVYIVKVPYCLR
                     ISEEIKIYEKLLNHSELTHAPCAPGTLETLSRFSILSRLKEPENSSIYSKMRVYDGES
                     LKDTDPKAKSYQEYRDYAGVDEGMNGLSTRFAFKILSRVFNFDHVEVAANPVHLFYVL
                     EQQIEREQFPQEQAERYLEFLKGYLIPKYAEFIGKEIQTAYLESYSEYGQNIFDRYVT
                     YADFWIQDQEYRDPDTGQLFDRESLNAELEKIEKPAGISNPKDFRNEIVNFVLRARAN
                     NSGRNPNWTSYEKLRTVIEKKMFSNTEELLPVISFNAKTSTDEQKKHDDFVDRMMEKG
                     YTRKQVRLLCEWYLRVRKSS"
     gene            4160..>5436
                     /locus_tag="RN951_004316"
     CDS             4160..>5436
                     /locus_tag="RN951_004316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaH/YhbH family protein"
                     /protein_id="HDX2529208.1"
                     /translation="MTWFIDRRLNGKNKSMVNRQRFLRRYKAQIKQSISEAINKRSVT
                     DVDSGESVSIPTEDISEPMFHQGRGGLRHRVHPGNDHFVQNDRIERPQGGGGGSGSGQ
                     GQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGYTANGV
                     PANISVVRSLQNSLARRTAMTAGKRRELHALEENLAIISNSEPAQLLEEERLRKEIAE
                     LRAKIERVPFIDTFDLRYKNYEKRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILL
                     YLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYNP
                     AQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEHL
                     QSTFDNFAMQHIRDQDDIYPVFRELFHKQNATA"
BASE COUNT         1412 a         1359 c         1339 g         1326 t
ORIGIN      
        1 gcgcagtttt tccttttggt gccggatatg ccttatccag catagctaat tccgctgaag
       61 aaagttcgac ctcaagcaca gccgcatttt gttggacatg ggcaatcgtg gccgcttttg
      121 gaatcgccat cacaccctga tgactgatca cccacgccaa caatacttgt gccgcgctga
      181 tattgtgagc atgtgcaatt tcgttgacta ccgcgttttt taacagtcca ttgcgcaacc
      241 gcccggcctg ggctaacgga ctgtaagcca tcaccggcat ctgctgttgc tggcaccagg
      301 ggagtagatc gtactcaatt cctcgtgaac cgagatggta aagcacctga ttagtggcac
      361 actgatttcc ccccggcagc tgccagagtt cctgcatatc agcataatca aggttagaaa
      421 cgccccagcg gcggattttt ccctgggcga tcaatttttc catcgctgcg acagtctctt
      481 caaaagcgaa actgccagac cagtgtaata agtaaagatc gagataatca gtattgagac
      541 ggcgtaaact ggcttcgcat gcatttatcg ctttttgccc gccagcattc cacggataga
      601 ctttagagac gagaaagacc ttctctcgca gaccggttaa tgcttcccca accacctttt
      661 cggcaccgcc atcggcatac atttcggcgg tatcaatgag ggttaaaccg agttcaatgc
      721 ccgcgcgtag tgcagcaact tctgttttgc gctgactggc atcttcgccc atataccatg
      781 ttccctgccc tacggctggc agtgagacat cgccactaaa ttgaatcatt ttttgttgca
      841 ttgtttcctc ccaggtattg caccaccgta atgcaaaaca gggcgtgacg ccctgttttt
      901 atgcacaaaa tgccctggaa agatgcatta tcagaatttg taggtgatcc cggtagaaat
      961 caggccagtc caggatttat ccaccatcgg gctgtcagta acttcatcag acagacgggt
     1021 gtagcgtgcg gtaccgtaaa cactccagtc gccgaggaag ttgtagctgg cgctcagctc
     1081 caggtaaggg ctccagctgt cgttcgggtt atagccacgc agaccgctgc gagcggactc
     1141 tttgcgcgat acgccataat agtattcgtt ctggttttcg ctgttccact gcacaccaat
     1201 acccggagtc acggtcaggc caccgttggt gtaacgatac aaccaggcca tatcccagac
     1261 gatgccgttg ctgttatcca gggtatcgcc agccagggtg gtacgcaggt aaccgtactg
     1321 ggtaaagtga gcataagaca gaccagccat catggtgctc ttacggtcat ccaggtgacg
     1381 catttggtga tcgccactgt ctttcgcttt gaagtaaagc ggcgaccagt aagcggtaat
     1441 tgaaagttta tccgttgcgt cattccacag gtagtaacca ccacctaagc cacggaacca
     1501 gaagttatcg ccttcatagt tgattaccgg tactgggtaa acatcggtat cgtaatcttt
     1561 atatgggtgt tcaacgacac ctacgcctgc gcccagggaa aatttacctt cagcgtgcgc
     1621 tacgcctgca gacgttgcga taagcactcc aagtgccaga agtttgagtt tggtcacaat
     1681 taatcattcc ttaaacaaat gtttagcggg cgacaaagtt tacccgtcaa tacatcgaaa
     1741 cccaaccttt ttacgttttc attttttaaa gtaactgttt aattttcctg acgcggatga
     1801 caccgcgctt acagccaaat gaatttagcg ttactggcga gcctggtctt tacattaatt
     1861 atgcaaaatt tatggatgag ttgttgatat gccattgaaa ttaagaaagc cgtgcaggca
     1921 agttttccat ttgccatcta cgcttaattt tgaaggtgta tcaccgggca cgttgttctc
     1981 atcgtcgata aaatggcatg agagttgctg tgttttagca agagacgtcg ttcagtttac
     2041 ctcttccggg agcctctact attcatatga acggctctta acctgtgcta aaaaacgaaa
     2101 ggacggcata ccatgaatat attcgatcac tatcgccagc gatatgaagc tgccaaggac
     2161 gaagagttca cactgcagga gtttcttacc acttgtcggc aagatcgcag tgcttatgcc
     2221 aacgcggctg agcggctatt gatggctatc ggtgagcctg tcatggtcga tacagcccag
     2281 gaacccagac tttctcgact cttttctaac cgggtcattg cacgttatcc ggcgtttgaa
     2341 gagttttacg gcatggaaga cgcgattgaa cagattgtct cttatctgaa acacgcggct
     2401 caggggctgg aagagaagaa acaaatcctg tatctgctgg ggcctgtggg tgggggtaaa
     2461 tcatcgcttg ctgagcgact gaaatcatta atgcagctcg taccgattta tgtattgagc
     2521 gcgaacggtg agcgtagccc ggtcaacgat catccgttct gtcttttcaa tccgcaggaa
     2581 gatgcgcaga ttctggaaaa agagtatggc attcctcgcc gttatctcgg caccatcatg
     2641 tcgccgtggg cggcaaaacg cctgcatgaa tttggtggcg atatcactaa gttccgggta
     2701 gtgaaggtct ggccgtcaat tctgcaacaa attgctatcg ccaaaacgga acccggcgat
     2761 gagaacaacc aggacatctc cgcgctggtt gggaaagtcg atattcgtaa actcgaacac
     2821 tacgcgcaga atgacccgga cgcctacggc tattccggtg cgctgtgccg cgccaatcag
     2881 gggatcatgg aattcgttga gatgtttaaa gcaccgatta aagtgctgca tcccttgtta
     2941 accgccactc aggaaggtaa ctacaacggg acggaaggta tctccgccct gccgttcaac
     3001 gggattattc tcgcacactc gaacgagtcc gaatgggtca ctttccgtaa taacaaaaac
     3061 aacgaagcct tcctcgatcg tgtttacatc gtgaaggtgc cgtattgctt gcgcatttcc
     3121 gaagagatca aaatctacga gaaattgctt aatcacagtg aattgactca cgccccatgc
     3181 gcccctggca cgctcgaaac actgtcacgt ttttccattc tttcgcgcct gaaagagcca
     3241 gaaaactcca gcatttattc aaagatgcgg gtttatgatg gcgaaagtct gaaagacacc
     3301 gatcccaaag ccaagtcgta tcaggaatat cgtgactacg ccggtgtcga tgaagggatg
     3361 aacggtctgt cgacgcgttt tgcgtttaag atcctctccc gcgtgttcaa cttcgatcat
     3421 gtagaagtgg cagcaaaccc ggtccatctg ttctacgtcc tggaacagca gattgagcgc
     3481 gagcagttcc cacaagagca ggcagaacgc tatctggagt tcctgaaagg ttatctgatc
     3541 ccgaaatatg ccgagtttat cggcaaagag atccagacgg cctaccttga atcctattcc
     3601 gaatatgggc aaaacatttt cgaccgttat gttacctacg cggatttctg gattcaggat
     3661 caggagtatc gcgatccgga taccgggcag ctgtttgacc gcgagtctct taacgccgag
     3721 ctggagaaaa tcgagaaacc ggcggggatc agtaatccaa aagatttccg caacgagatt
     3781 gttaacttcg tactgcgcgc cagagcgaat aacagcggac gcaatccgaa ctggaccagc
     3841 tatgaaaaac tgcgcacggt catcgagaag aaaatgttct ccaataccga ggagctgttg
     3901 ccggttatct cgtttaacgc caaaacgtca accgacgagc agaagaaaca cgacgacttt
     3961 gtcgaccgta tgatggaaaa aggctacacc cgtaaacagg tgcgtttact gtgcgaatgg
     4021 tatttgcgcg tacgtaaatc gtcttaacaa ccctggcccg gtacacatgt taccgggcct
     4081 acaacgacag cgaaccgtgg gcctgagaag cggcaacaca ggcgtagcat acagttggca
     4141 aatgtagtac ggggggcata tgacctggtt tattgaccgg cgtctgaacg gcaaaaacaa
     4201 aagcatggtg aatcgccagc gttttttacg ccgttataaa gcgcaaatta aacagtcgat
     4261 ctccgaggcc attaataagc gttcggtgac tgacgtcgac agcggcgaat ccgtatccat
     4321 tcccacggaa gatattagcg aaccgatgtt tcatcagggg cgtggcggtc tgcgccaccg
     4381 cgtgcatccg ggcaatgacc atttcgtcca gaacgaccga attgaacgtc cccagggtgg
     4441 cggcggaggt tccggcagtg gtcagggcca ggccagccag gatggtgaag gtcaggatga
     4501 atttgtcttt cagatttcga aagatgagta tcttgatctg ctctttgaag atttggcctt
     4561 accgaatctg aaacaaaacc aacaacgcca gctgaccgaa tataaaacgc atcgggcggg
     4621 ttataccgct aacggcgttc cggccaatat cagcgttgtg cgttcattgc agaactcact
     4681 ggcgcgacgc acagccatga cggcaggcaa gcggcgggaa cttcatgcac tggaagagaa
     4741 tttggccatc atcagcaaca gtgaacctgc gcaactgctg gaagaggaac gtctgcgcaa
     4801 agaaattgca gaattacgtg ccaaaattga acgcgtccct tttattgaca ccttcgattt
     4861 acgttacaag aactacgaga agcggcccga tccctccagc caggcagtga tgttttgcct
     4921 gatggacgtt tccggttcaa tggatcaatc cactaaagat atggctaagc gtttttatat
     4981 tctgctgtat ctgttcctca gcagaacgta taagaacgtg gaagtcgtat acatccgcca
     5041 tcatacccag gcgaaagaag tcgatgaaca tgagtttttc tactcgcagg aaacaggcgg
     5101 caccattgtt tccagcgccc tgaaactgat ggatgaggta gtgaaagagc gttataaccc
     5161 ggcacagtgg aatatttacg ctgcacaagc atcggacggc gataactggg ccgatgactc
     5221 tccgctttgc catgaaatcc tggcgaaaaa attattacct gttgttcgtt attacagcta
     5281 tatcgaaatt acccgtcgtg cacatcagac attgtggcga gaatatgagc atctgcaatc
     5341 tactttcgac aactttgcga tgcagcacat ccgcgaccag gatgatattt atccggtgtt
     5401 ccgtgaactg tttcataaac aaaatgcaac agctaa
//
LOCUS       DAPOAV010000170         5420 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.171, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000170 DAPOAV010000000
VERSION     DAPOAV010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5420
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.171"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(129..1412)
                     /gene="aroA"
                     /locus_tag="RN951_004317"
     CDS             complement(129..1412)
                     /gene="aroA"
                     /locus_tag="RN951_004317"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDX2529209.1"
                     /translation="MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNL
                     LDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPL
                     AAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGG
                     NVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQ
                     HYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRF
                     ADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNI
                     YNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFS
                     LVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA"
     gene            complement(1483..2571)
                     /gene="serC"
                     /locus_tag="RN951_004318"
     CDS             complement(1483..2571)
                     /gene="serC"
                     /locus_tag="RN951_004318"
                     /EC_number="2.6.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoserine/phosphohydroxythreonine
                     transaminase"
                     /protein_id="HDX2529210.1"
                     /translation="MAQIFNFSSGPAMLPAEVLKQAQQELRDWNGLGTSVMEVSHRGK
                     EFIQVAEEAEKDFRDLLNVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAGYW
                     AASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMREWQLSDNAAYMHYCPNETIDGIAID
                     ETPDFGADVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKA
                     NIACPSILDYSILNDNGSMFNTPPTFAWYLSGLVFKWLKANGGVAEMDKINQQKAELL
                     YGVIDNSDFYRNDVAKANRSRMNVPFQLADSALDKLFLEESFAAGLHALKGHRVVGGM
                     RASIYNAMPLEGVKALTDFMVEFERRHG"
     gene            complement(2770..3462)
                     /locus_tag="RN951_004319"
     CDS             complement(2770..3462)
                     /locus_tag="RN951_004319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HDX2529211.1"
                     /translation="MKAFDLHRMAFDKVPFDFLGEVALRSLYTFVLVFLFLKMTGRRG
                     VRQMSLFEVLIILTLGSAAGDVAFYDDVPMVPVLIVFITLALLYRLVMWLMAHSEKLE
                     DLLEGKPVVIIEDGELAWSKLNNSNMTEFEFFMELRLRGVEQLGQVRLAILETNGQIS
                     VYFFEDDKVKPGLLILPSDCTQRYKVVPESADYACIRCSEIIHMKAGEKQLCPRCANP
                     EWTKASRAKRVT"
     gene            3592..5352
                     /locus_tag="RN951_004320"
     CDS             3592..5352
                     /locus_tag="RN951_004320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415425.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HDX2529212.1"
                     /translation="MTQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVW
                     SVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVH
                     YPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTR
                     QSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPE
                     IPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGA
                     HPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDL
                     FKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSD
                     IYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLG
                     LATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQ
                     TLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAH
                     QSLLKAYEKLQRAKAAFWAK"
BASE COUNT         1400 a         1404 c         1279 g         1337 t
ORIGIN      
        1 tcaacaactt acattgacaa gcgacgctac cattaatcaa aatgactcac aaggtccgaa
       61 aaaaaacgcc gacaatgtgc cgacgttttg ataaagaaag atttggctat ttattgcccg
      121 ttgttcattc aggctgcctg gctaatccgc gccagctgct cgaaataatc cggaaatgtt
      181 ttggccgtgc atttgggatc aagaatcgtc actggtgtat ctgacaacgc caccagcgag
      241 aaacacatcg ccatccggtg atcattgtat gtcgcgatct cggcaaagtt cagtttttcc
      301 ggaggagtga tacgaatgta atcgtgcccc tcttccactt ccgcgccgac tttacgcagt
      361 tctgttgcca tcgcaaacag gcgatcggtc tctttaacac gccagttata gatattgcgc
      421 agcgtggtgg tgccttttgc aaataacgcc gccgtggcaa tggtcatcgc cgcatcagga
      481 atatggttca tatccatatc aatagcgttc agttcaccac gcgtgcagga aatataatca
      541 tcgccccagc aaatggtcgc gcccattttt tccagcacat cagcaaagcg aatatcaccc
      601 tgcatactgt tacgtccaat accggtcact tttacagtgc cgcctttgat tgctgctgct
      661 gccagaaagt aagaagccga agatgcatcg ccttcgacca aataagtacc cggagactga
      721 taagactgcc cgccttttac gacaaattgt tgatagtgct gattttcaat ttcaacacca
      781 aacgtcttca tcagattgag tgtgatgtcg atataaggtt tagaaaccag atcgccttta
      841 atacgaatca ccgtatcttc cggcgcaaga ggcgcagtca ttaacagtgc ggtgaggaat
      901 tggctggaaa cggagccatc aacgtcaacg ttgccgccag taaagccgcc ctgtaaacgc
      961 aacggcggat aattttcttg ttccaggtaa gtgatcttcg ccccgcccag gcgcagcgca
     1021 tccaccagat gaccaatcgg gcgttctttc atacgcggct caccggtcag cacaatatca
     1081 ttgctaccca gacaaagagc tgccgccagc ggacgcattg ccgttccggc gttaccgagg
     1141 aacaactcca gggcaccttc tgcgtgtaat ggaccgccgt taccgataat ttcgcaacgc
     1201 gtacgatcgg ctgaaagcgt atagcttacc cctaacgctg ttaatgcatt cagcatatgg
     1261 cgcacgtcat cgctatccag cagattggtt aatactgttt tgccgtgtgc taatgccgcc
     1321 agcaataaag cgcggttaga aacgctcttg gaaccgggca gattaatagt gccatcgaca
     1381 cgagcgatgg gttgtaacgt cagggattcc atgaactcaa ctctctacaa cagaaataaa
     1441 aaccccacag gctggctgtg gggattaagc aaaatttcgg cattaaccgt gacggcgttc
     1501 gaactcaacc atgaagtctg tcagcgcttt aacgccttcc agcggcatgg cgttataaat
     1561 agaagcgcgc attccgccga ccacacggtg acctttcagt gcatgaaggc cagcagcaaa
     1621 agactcttca aggaacaatt tgtcaagcgc actgtccgcc aactggaacg gcacgttcat
     1681 ccgcgaacgg ttagctttcg ccacgtcatt gcggtagaaa tcgctgttat caatcacccc
     1741 atatagcagt tctgcttttt gctgattgat tttatccatt tcagctacac cgccgttcgc
     1801 tttcagccat ttaaagacca gaccagatag ataccaggca aatgtcggcg gcgtgttaaa
     1861 catggagccg ttatcgttga ggatggaata atccagaatc gacggacacg cgatattcgc
     1921 tttgcccagc aaatcttcac gaacgatgac gattgtcagg ccagccgggc cgatattttt
     1981 ctgcgcgcca gcgtaaatta caccataacg gctgacgtca atcggacggg aaagaatggt
     2041 tgaagagaag tcagcggcga ccaccacatc tgcgccgaag tctggcgttt cgtcgatggc
     2101 gataccatcg atggtttcat tcgggcaata atgcatataa gcagcattat cagagagttg
     2161 ccattcacgc attggcttaa ccgcgcgcag accatcaaca gtcactttgg cgtcaaagac
     2221 attaggcgtg cagtattttt tcgcttcttt aatggcactt gccgcccagt aaccggcatc
     2281 aacataatct gcggtggttt tatcaccgag aatattcagc ggtaccgcag caaactgacc
     2341 gcgaccaccg ccatggcaga ataatacctt gtagttggag gggacattaa gaagatcgcg
     2401 aaaatccttc tcggcttcct ctgcaacctg aatgaactct ttgccacggt gactcacttc
     2461 catcaccgac gtaccaagac cgttccagtc gcgcagttcc tgttgagcct gtttaagcac
     2521 ctctgccggt agcattgccg gaccagaact aaaattgaag atttgagcca tttcccctca
     2581 ccacgttgcg ttgctattaa cccgcggtca atcgattgcg accacaggta atacattatt
     2641 cctgtggcta tcggttttat cattcagtga cacacatcgc aatgagtaaa accgttgagg
     2701 gcaaaaatgt ggcttgcatc acacaaaaga atctctcgga ttattagcaa aaagccgatg
     2761 tttttactgt caggtcaccc gttttgcccg acttgccttc gtccattctg gatttgcaca
     2821 gcgcggacat aattgttttt cccccgcttt catatgaatg atttcactac aacgaataca
     2881 ggcatagtcc gccgactccg gcaccacttt gtaacgctgc gtacaatcac tgggtaaaat
     2941 aagtaaaccc ggtttcacct tgtcatcttc aaagaaatag acactgattt gcccgttggt
     3001 ttcgagaatc gccagacgta cctgccccag ctgctccacg ccacgcaatc gtagctccat
     3061 aaagaactca aattccgtca tgttggagtt attgagtttc gaccaggcca gctcgccatc
     3121 ttcaataatg acaactggct tgccttccag aagatcttcc agtttttcac tgtgcgccat
     3181 caaccacatt accaggcggt ataacaacgc cagagtaata aagacgataa gtaccgggac
     3241 catcggcaca tcatcataaa acgccacatc tcccgccgct gatcccagcg tcagaatgat
     3301 taaaacttca aacagcgaca tctgccgcac accgcgtctt ccggtcattt tgaggaacaa
     3361 aaagaccagt acaaaggtat aaagactacg tagtgcaact tcgccaagga aatcaaaagg
     3421 cactttatca aatgccatac ggtggagatc gaacgccttc atttttatgc tcttaacgtg
     3481 gtttatccgc taaaagcata gtcaacagtt catcggcatg gcggcggtga tagcgccttt
     3541 gagataaaac ccgtattatt gcgcgctttc cgtacgacta aagtgatttt catgacgcaa
     3601 acatttatcc ccggcaaaga tgccgctctg gaagattcca tcgctcgctt ccagcaaaaa
     3661 ctttcagacc tcggctttca gattgaagag gcctcctggc tgaatcccgt gcctaacgtc
     3721 tggtctgtac atattcgcga caaagagtgc gcactgtgtt ttaccaacgg taaaggcgca
     3781 accaagaaag cggcgctggc ttctgcactc ggtgaatatt tcgagcgtct ctcaaccaac
     3841 tacttttttg cggacttctg gctgggcgaa accatcgcca acggtccgtt cgtgcattat
     3901 cccaacgaaa aatggttccc actgaccgaa aatgacgatg tgccagaagg gctgctcgat
     3961 gaccgtctgc gcgcgtttta tgatccggag aatgaactga ccggcagcat gctgattgac
     4021 ctacaatccg gtaacgaaga tcgtggtatt tgcggcctgc cgtttacgcg tcagtccgac
     4081 aatcagaccg tttatattcc gatgaatatc attggtaacc tgtacgtctc caacggtatg
     4141 tccgcaggta atacccgcaa cgaagcacgc gttcagggat tgtctgaagt tttcgaacgc
     4201 tacgtgaaaa accgcattat tgctgaaagc atcagcctgc cagagatccc ggcagacgtg
     4261 ctggcgcgtt acccagcagt agttgaagcc atcgaaacgc tggaagcgga gggtttccca
     4321 atcttcgctt atgacggttc gcttggcggc cagtatccgg tgatttgcgt ggtactgttc
     4381 aatcctgcta acggtacctg ctttgcctct ttcggtgcgc atcctgattt tggcgtagca
     4441 ctggaacgta ccgtgaccga gctgctgcaa ggtcgtggcc tgaaagattt ggatgtgttt
     4501 actccgccaa ccttcgatga tgaagaagtc gctgaacata ccaacctcga aacgcacttt
     4561 atcgattcca gcggtttaat ctcctgggac ctgttcaagc aggatgccga ttatccgttt
     4621 gtggactgga atttctccgg caccacggaa gaagagttcg ccacactgat ggctatcttc
     4681 aacaaagaag ataaagaagt ttatattgcc gattacgagc atctgggcgt ttatgcttgc
     4741 cgtattatcg tgcctggcat gtccgatatt tatccggctg aagatctgtg gctcgcgaat
     4801 aacagtatgg gcagccattt acgtgaaacg attctttcgc taccaggcag cgagtgggaa
     4861 aaagaagatt acctgaacct catcgagcaa ctggatgaag aaggttttga tgactttacc
     4921 cgcgtgcgtg agctgttggg tctggcgacc gggtcggata acggttggta caccctgcgt
     4981 atcggtgaat taaaagccat gctggcgctg gctggtggcg atctggaaca ggctctggtc
     5041 tggaccgaat ggacgatgga gtttaactca tcagtattta gtccggaacg cgccaactat
     5101 tatcgctgcc tgcaaacgtt gttattactg gcacaggaag aagatcgcca gccgctgcaa
     5161 tatctgaatg cgtttgttcg catgtacggc gcagatgccg tagaagccgc cagtgcggca
     5221 atgagcggcg aagcggcgtt ttacggcctg caaccggtag atagcgatct gcacgcgttt
     5281 gctgcacatc agtcgttgtt gaaggcctac gaaaagctgc agcgcgccaa agcagcattc
     5341 tgggcaaaat aaaatcaaat agcctacgca atgtaggctt aatgattagt ctgagttata
     5401 ttacggggcg tttttttaat
//
LOCUS       DAPOAV010000171         5355 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.172, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000171 DAPOAV010000000
VERSION     DAPOAV010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5355
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.172"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..1653)
                     /locus_tag="RN951_004321"
     CDS             complement(<1..1653)
                     /locus_tag="RN951_004321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative relaxase"
                     /protein_id="HDX2529213.1"
                     /translation="MLSFSVVKSAGSAGNYYTDKDNYYVLGSMGERWAGQGAEQLGLQ
                     GSVDKDVFTRLLEGRLPDGADLSRMQDGSNKHRPGYDLTFSAPKSVSMMAMLGGDKRL
                     IDAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQDPQLHTHV
                     VVANVTQHNGEWKTLSSDKVGKTGFSENVLANRIAFGKIYQSELRQRVEALGYETEVV
                     GKHGMWEMPGVPVEAFSSRSQAIREAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAE
                     WMQTLKETGFDIRAYRDAADQRAEIRTQAPGPASQDGPDVQQAVTQAIAGLSERKVQF
                     TYTDVLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSV
                     RALSRDIMKQNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVA
                     ELVMMAREQGREVQIIAADRRSQMNLKQDERLSGELITGRRQLQEGMVFTPGSTVIVD
                     QGEKLSLKETLTLLDGAARHNVQVLITDSGQRTGTGSALMAMK"
     gene            complement(1653..3797)
                     /gene="traD"
                     /locus_tag="RN951_004322"
     CDS             complement(1653..3797)
                     /gene="traD"
                     /locus_tag="RN951_004322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000009331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system coupling
                     protein TraD"
                     /protein_id="HDX2529214.1"
                     /translation="MSFNAKDMTQGGQIASMRIRMFSQIANIMLYCLFIFFWILIGLV
                     LWVKISWQTFINGCIYWWCTSLEGMRDLIKSQPVYEIQYYGKTFRMNAAQVLHDKYMI
                     WCGEQLWSAFVLASVVALVICLITFFVVSWILGRQGKQQSENEVTGGRQLTDNPKDVA
                     RMLKKDGKDSDIRIGDLPIIRDSEIQNFCLHGTVGAGKSEVIRRLANYARQRGDMVVI
                     YDRSGEFVKSYYDPSIDKILNPLDARCAAWDLWKECLTQPDFDNTANTLIPMGTKEDP
                     FWQGSGRTIFAEAAYLMRNDPNRSYSKLVDTLLSIKIEKLRTFLRNSPAANLVEEKIE
                     KTAISIRAVLTNYVKAIRYLQGIEHNGDPFTIRDWMRGVREDQKNGWLFISSNADTHA
                     SLKPVISMWLSIAIRGLLAMGENRNRRVWFFCDELPTLHKLPDLVEILPEARKFGGCY
                     VFGIQSYAQLEDIYGEKAAATLFDVMNTRAFFRSPSHKIAEFAAGEIGEKEHLKASEQ
                     YSYGADPVRDGVSTGKDMERQTLVSYSDIQSLPDLTCYVTLPGPYPAVKLSLKYQARP
                     KVAPEFIPRDINPEMENRLSAVLAAREAEGRQMASLFEPEVASGEDVTQAEQPQQPVS
                     SVINDKKSDAGVSVPAGGIEQELKMKPEEEMEQQLPPGISESGEVVDMAAYEAWQQEN
                     HPDIQQHMQRREEVNINVHRERGEDVEPGDDF"
     gene            complement(3848..4585)
                     /locus_tag="RN951_004323"
     CDS             complement(3848..4585)
                     /locus_tag="RN951_004323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529215.1"
                     /translation="MTSDNIAEYVGENNQFTEKPVTEYPPVIQDNTVTTKDYLYSNNI
                     DTDLLVVIGGLIVILFLMMLIMYFINSLRHKELTEILTKISFPEKSGSNLLKPEAVSC
                     NLLSLCVLAPVFCTPRKLAEVSREIIVASAQEIAWTPGSSRIDGHQAENITWAISSQS
                     PADKYDLINKTSCVSPDSGRFYEPDTVLDHRERVRLFIQIQFPHGSDWSEVLRLTDIV
                     TEKVSSGRTAGGHHHRHTGYTWSVSVN"
     gene            complement(4788..5327)
                     /locus_tag="RN951_004324"
     CDS             complement(4788..5327)
                     /locus_tag="RN951_004324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309339.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complement resistance protein TraT"
                     /protein_id="HDX2529216.1"
                     /translation="MSGLQGKIADAVKAKGYQVVTSPDKAYYWIQANVLKADKMDLRE
                     SQGWLNRGYEGAAVGAALGAGITGYNSNSAGATLGVGLAAGLVGMAADAMVEDVNYTM
                     ITDVQIAERTKATVTTDNVAALRQGTSGAKIQTSTETGNQHKYQTRVVSNANKVNLKF
                     EEAKPVLEDQLAKSIANIL"
BASE COUNT         1228 a         1563 c         1269 g         1295 t
ORIGIN      
        1 cttcatggcc atcagcgcac tgcctgtacc ggttcgctgc ccgctgtcgg ttatcaggac
       61 ctgtacgtta tgacgtgcgg caccatccag cagggttaac gtctctttca gggagagttt
      121 ttcgccctgg tcgacgataa cagtactgcc cggcgtgaag accatgccct cctgcagctg
      181 acgacgtccg gttatcagct caccggacag ccgttcatcc tgcttcaggt tcatctgcga
      241 gcgacggtca gcagcgataa tctgcacctc ccgcccctgc tcccgggcca tcatgaccag
      301 ttcagccacc cgctcacgct gcccggctgc accgccctgc ccggacacaa tggccagcga
      361 cggacggtcc tgtgccagaa cactgaccgc atcgctgtaa ccagccgtcc gggggacact
      421 tttctccgga tgtacggtca cccggttctg tttcatgatg tcacgactga gtgcccggac
      481 ggacagctca tcgagcacat gaattcctga tgtgaacagc cccttctcac ggtcgagggg
      541 gataagctgc tcacggctga tggcctcatc gataccggcg cgtgcccgtt caatcacacc
      601 attttccggc ggcagtatgc cgaccgtcct ggccagcacg tccgtatacg tgaactgcac
      661 ttttcgttca cttaatccgg caatcgcctg tgtcaccgcc tgctgcacat ccggcccgtc
      721 ctgtgaagca ggcccgggcg cctgcgtgcg gatctccgca cgctgatccg ccgcgtcacg
      781 atatgcccgg atgtcgaacc cggtttcctt cagcgtctgc atccattcag ccattctgac
      841 ttcaggatcg acgtgctgtt tggattttcg cgtatccagt gccgccacat cccgggattt
      901 cagcgaggcg tcttcaccga cggcctccct gatagcctgt gaacgactgg aaaaggcctc
      961 caccggtacg cccggcatct cccacatacc gtgcttaccg accacttcgg tttcataacc
     1021 cagcgcctca acgcgctgac gtaactcact ctgatatatt ttcccgaacg caatccggtt
     1081 cgctagcacg ttctcggaaa atccggtttt ccccactttg tcactgctca gtgtcttcca
     1141 ctcgccgtta tgctgcgtga cattagccac cactacatgc gtgtgtaact gtgggtcctg
     1201 atcgcgactg gtgtcatggt taaacagtgc catcaccaga ttaccggtca gcaccgtttc
     1261 tgactgtccg tccgtcatca cccgtgtgga agccagcgcc tccacctgac ggacagcaaa
     1321 atccacggcc tggttatgtg catcaataag acgtttatcc cccccgagca tggccatcat
     1381 ggagacactt ttgggggcgg agaaggtcag gtcgtagccg ggacgatgct tattactgcc
     1441 atcctgcatg cggcttaaat ccgccccgtc cggcagcctg ccctccagaa gacgggtaaa
     1501 aacatcctta tcgacgctgc cctgcagccc aagctgttca gccccctgac cagcccagcg
     1561 ttctcccatg ctgcccagca catagtaatt atccttgtcg gtgtaatagt ttccggcact
     1621 gcctgccgat ttaacaacgc tgaaactcaa catcagaaat catctcccgg ctcaacatcc
     1681 tccccgcgct cccggtgcac attaatgttc acctcttcac gacgctgcat atgctgctgg
     1741 atgtccggat gattttcctg ttgccatgcc tcataagcgg ccatatccac cacttcaccg
     1801 gattcactga tcccgggtgg cagttgctgt tccatctctt cttccggttt cattttcagc
     1861 tcctgctcga tcccccctgc cggaacactc acacctgcat ctgacttctt atcattgatg
     1921 acagaagaca ctggctgttg tggctgttca gcctgagtca catcttctcc ggaggcaacc
     1981 tccggttcaa agaggctggc catctgacga ccttctgctt cccttgcggc aagtacggca
     2041 ctcagacggt tctccatttc cgggttgatg tcacgcggaa taaactccgg agcgaccttc
     2101 ggtcgtgcct gatatttcag agagagtttg actgccggat acggtccggg cagagtgaca
     2161 tagcaggtca gatccggcag agactgaatg tcggaataac tgaccagcgt ctgacgctcc
     2221 atatccttac cggtcgatac cccgtcacgt accgggtcag caccgtagga atactgctcg
     2281 ctggctttca ggtgctcttt ctcaccaatc tcaccggcag cgaactctgc aatcttatgg
     2341 ctcggggaac ggaaaaaagc acgggtgttc atgacgtcaa acagcgtggc cgccgctttc
     2401 tcaccgtaga tatcttccag ctgggcatag gactggatac caaacacata acagccaccg
     2461 aacttacggg cttccggcag gatctccacc agatccggca gtttgtgtaa cgtgggtaac
     2521 tcatcacaga aaaaccacac acgacggtta cggttttctc ccattgccag cagaccacga
     2581 atggcaatgg acagccacat ggagatcaca ggcttcaggg aggcatgggt gtcggcgttc
     2641 gacgaaataa acagccagcc gtttttctga tcttcccgga caccacgcat ccagtcacgg
     2701 atggtgaagg gatcaccgtt atgctcaatc ccctgcaggt aacggatggc tttcacgtag
     2761 ttggtcagca cagcacggat ggaaatcgcc gttttctcaa ttttctcttc caccaggttg
     2821 gccgccggtg aattacgcag gaaggtacgc agtttttcaa ttttgatgga aagcagtgtg
     2881 tccaccagtt tgctgtagct gcggttgggg tcattacgca tcaggtacgc cgcttccgca
     2941 aaaatggtac gtcctgaacc ctgccagaac gggtcctctt ttgtacccat agggatcagc
     3001 gtgttcgcgg tattatcaaa atccggctgt gtcaggcact ccttccacaa atcccatgcg
     3061 gcacagcggg catccagcgg attcaggatt ttatcgatgg agggatcata gtaactttta
     3121 acaaattccc ctgaacggtc ataaatcacc accatatcac cgcgctgacg ggcatagttg
     3181 gccagacgac ggataacctc cgacttaccg gccccgaccg tgccgtgcag acagaagttc
     3241 tggatttcgg aatcccggat aatcggcagg tcgccaatcc ggatatcgga gtccttgccg
     3301 tcttttttca gcatccgggc aacgtctttc ggattgtctg tcagctgacg accacctgtg
     3361 acttcatttt cgctctgttg tttaccctga cgccccagaa tccaggagac aacaaagaag
     3421 gtgatcaggc aaataaccag ggccacgaca gacgccagaa cgaatgcaga ccatagctgc
     3481 tctccgcacc agatcatata tttatcatgc agtacctggg cagcgttcat ccggaaggtt
     3541 ttgccgtaat actggatctc atagaccggc tgggatttta ttaaatcccg catgccttcc
     3601 agtgacgtac accaccagta aatacagccg ttgataaacg tctgccagct tatttttacc
     3661 cataagacca gaccaatgag gatccagaaa aaaataaaca ggcagtaaag catgatattg
     3721 gcgatctggc tgaacatgcg gatacgcatg gacgcaatct gaccgccctg ggtcatatcc
     3781 tttgcgttaa aactcatgat gaaactccgg gaaaatctgg aacagggcag aaaaggatga
     3841 tgtggggtta attcacagaa acagaccagg tgtaccctgt atgccggtgg tgatgcccgc
     3901 ctgcagtcct gccggaagag accttctctg taacaatgtc agtcaggcgc aatacttcag
     3961 accagtcact cccatgcgga aactggatct gaataaaaag gcgtacccgt tcacggtgat
     4021 ccagaactgt gtccggttca taaaaacggc cactgtcagg agaaacacag gacgttttat
     4081 tgatgagatc atacttatcg gcaggagact gcgatgaaat cgcccaggtg atattctccg
     4141 cctggtggcc atcaatacga ctgctccccg gcgtccatgc aatttcctgc gcactcgcca
     4201 cgatgatctc cctggaaact tcagccagct ttctgggtgt acagaatacc ggtgccagca
     4261 cacacaggga caacaaatta cagctgaccg cctccggttt aagcaaattg ctcccggatt
     4321 tttcaggaaa agatattttt gtcagtattt cagttaattc cttatgcctg agagaattaa
     4381 taaagtacat gataagcatc atgagaaaca atataacaat aagccctccg ataaccacta
     4441 aaaggtcagt atcaatatta ttgctgtaca gatagtcttt agtggtcact gtattatcct
     4501 gtatcaccgg ggggtattca gttacaggct tctcagtaaa ttgattattc tcaccaacat
     4561 attcagcgat attgtctgat gtcataatga ctttctccgg aagatcccgg cttcgccggc
     4621 aacacttcac ggtcgcacaa agaatttgca caaccgctca gtgttttcat atttatttcg
     4681 gaaacgccgg gaggtgacaa aatttatttt gttacatccc ggggttggac aacgagcaac
     4741 gcgaggcgtc agcaaggagg ccggtcagat cagcctcctg acgaggttca gagaatattt
     4801 gcgattgatt tggccagttg gtcttcgaga acaggcttcg cctcttcaaa tttcaggtta
     4861 accttgttcg catttgaaac cacacgggtc tggtatttat gctggttacc tgtttcagta
     4921 ctggtctgaa ttttcgcacc tgatgtgccc tgacgcaggg cggcaacatt atccgttgtc
     4981 accgttgcct tagtacgctc tgcaatctgt acatccgtga tcatggtata gttcacatct
     5041 tccaccatcg catctgcagc catacccacc agaccagcag caaggcctac accgagtgtg
     5101 gcaccggcag aatttgagtt atagccggta ataccggcac ctaacgctgc accaactgct
     5161 gcgccttcat aaccacggtt cagccatccc tgagactccc gcagatccat cttatcggcc
     5221 ttcagcacat tcgcctgaat ccagtagtag gctttatccg gagaagtcac cacctgatat
     5281 ccttttgctt tcacagcatc agcaattttg ccctgcagcc cactcatgtc tttatcagac
     5341 gtgtttttga tctgc
//
LOCUS       DAPOAV010000172         5253 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.173, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000172 DAPOAV010000000
VERSION     DAPOAV010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5253
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.173"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..453)
                     /locus_tag="RN951_004325"
     CDS             complement(<1..453)
                     /locus_tag="RN951_004325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708769.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HDX2529217.1"
                     /translation="MKTLSQNTTSSACAPETDLQQLVATLVPDEQRISFWPQHFGLIP
                     QWVTLEPRVFGWMDRLCEDYCGGIWNLYTLNNGGAFMAPEPDDDDDETWVLFNAMNGN
                     RAEMSPEAAGIAACLMTYSHHACRTECYAMTVHYYRLRDYALQHPECSA"
     gene            complement(795..1613)
                     /locus_tag="RN951_004326"
     CDS             complement(795..1613)
                     /locus_tag="RN951_004326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HDX2529218.1"
                     /translation="MRLASRFGYTNQIRRDRPLTHEELMHYVPSIFGEDRHTSRSKRY
                     AYIPTITVLESLQREGFQPFFACQTRVRDPGRRGYTKHMLRLRRAGEINGEHVPEIIL
                     LNSHDGTSSYQMLPGYFRFVCQNGCVCGQSLGEVRVPHRGNVVDRVIEGAYEVVGVFD
                     RIEEKRDAMQSLVLPPPARQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLWS
                     TYQTIQENMLKGGISGRSAKGKRIHTRAIHNIDTDIKLNRALWVMAETLLESLR"
     gene            complement(1768..1926)
                     /locus_tag="RN951_004327"
     CDS             complement(1768..1926)
                     /locus_tag="RN951_004327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001550547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HDX2529219.1"
                     /translation="MPGCTSRLLPEGPFSREQAVAVKTAYRNVFTEDDQGTYSRLVIR
                     NAEGQLRW"
     gene            complement(1997..4843)
                     /gene="ag43"
                     /locus_tag="RN951_004328"
     CDS             complement(1997..4843)
                     /gene="ag43"
                     /locus_tag="RN951_004328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Ag43"
                     /protein_id="HDX2529220.1"
                     /translation="MKRHLNTSYRLVWNHITGTLVVASELARSRGKRAGVAVALSLAA
                     VTSVPALAADTVVQAGETVNDGTLTNHDNQIVFGTANGMTISTGLEYGPDNEANTGGQ
                     WIQNGGIANNTTVTGGGLQRVNAGGSVSDTVISAGGGQSLQGQAVNTTLNGGEQWVHE
                     GGIATGTVINEKGWQAIKSGAVATDTVVNTGAEGGPDAENGDTGQFVRGNAVRTTINK
                     NGRQIVAVEGTANTTVVYAGGDQTVHGHALDTTLNGGYQYVHNGGTASDTVVNSDGWQ
                     IVKEGGLADFTTVNQKGKLQVNAGGTATNVTLKQGGALVTSTAATVTGSNRLGNFTVE
                     NGNADGVVLESGGRLDVLEGHSAWKTLVDDGGTLAVSAGGKATDVTMTSGSALIADSG
                     ATVEGTNASGKFSIDGTSGQASGLLLENGGSFTVNAGGLASNTTVGHRGTLTLAAGGS
                     LSGRTQLSKGASMVLNGDVVSTGDIVNAGEIRFDNQTTPDAALSRAVAKGDSPVTFHK
                     LTTNNLTGQGGTINMRVRLDGSNTSDQLVINGGQATGKTWLAFTNVGNSNLGVATSGQ
                     GIRVVDAQNGATTEEGAFALSRPLQAGAFNYTLNRDSDEDWYLRSENAYRAEVPLYTS
                     MLTQAMDYDRILAGSRSHQTGVNGENNSVRLSIQGGHLGHDNNGGIARGATPESSGSY
                     GFVRLEGDLLRTEVAGMSLTTGVYGAAGHSSVDVKDDDGSRAGTVRDDAGSLGGYLNL
                     THTSSGLWADIVAQGTRHSMKASSDNNDFRARGWGWLGSLETGLPFSITDNLMLEPQL
                     QYTWQGLSLDDGQDNAGYVKFGHGSTQHVRAGFRLGSHNDMTFGEGTSSRDTLRDSTK
                     HRVSELPVNWWVQPSVIRTFSSRGDMSMGTAAAGSNMTFSPSRNGTSLDLQAGLEARV
                     RENITLGVQAGYAHSVSGSSAEGYNGQATLNVTF"
BASE COUNT         1123 a         1503 c         1400 g         1227 t
ORIGIN      
        1 ggcgctgcat tccggatgct gcagggcgta atcccgcagc cggtaataat ggaccgtcat
       61 ggcataacac tccgtacgac aggcatgatg actgtacgtc atcagacagg cagcaatgcc
      121 ggcagcttcc ggactcattt cagcgcggtt accgttcatg gcattgaaca gtacccatgt
      181 ttcgtcatca tcgtcatccg gttcgggtgc cataaatgcc ccgccgttgt tcagggtgta
      241 cagattccag ataccaccgc agtagtcttc gcacagacgg tccatccagc cgaagacacg
      301 gggctccagg gtcacccact gtggaatgag gccaaagtgc tgcggccaga agctgatgcg
      361 ctgttcatca gggacgaggg tggcaaccag ttgttgcagg tcagtctccg gtgcacaggc
      421 cgaagaggtg gtgttctgag acaatgtttt catgtatgaa atccttgtaa tgtgaataaa
      481 tgagagggag taaaggtcgg gagctggcaa catcacgttc atcactgacc gtgatgaccc
      541 ggtaatatca gggatgaatg atattcggct gaaattccgg acagccgtac gcgtaaccgt
      601 tccggtcaca gacggatggc cagatgccat tgcctgtata ctcagtctgc acagactgat
      661 ttctccggga cggtaaagca gacgggtaca ccaggcgcac aggtcatcat cagaaatgga
      721 acgacacccc ggcagcgcct ccggggcgtc gggtgattct ggtgcctgaa tcacgccttc
      781 agggacatgc tgcatcagcg caggctctcc agcagcgttt ctgccattac ccacaatgcg
      841 cggttgagct taatatcggt gtcgatgttg tgaatggcac gggtgtggat acgttttcct
      901 tttgcactgc ggccggaaat cccgcctttc agcatattct cctggatggt ctgataagta
      961 ctccacaggt ccttaccgta atcctcccgg cgtcgtggcg tcagaatgtc ggcggtggtg
     1021 acgggctgat gttcgtcacc ataacggtaa gtcagtgccg cctgtgccag cgcctggcgt
     1081 gccggtggcg gcaggaccag cgactgcatg gcatcacgct tctcctctat ccggtcaaac
     1141 acgcccacca cctcgtaagc cccttcaatg actctgtcca ccacatttcc ccgatgcgga
     1201 acacgcactt cccccagaga ctgaccacag acgcatccgt tctgacagac gaacctgaag
     1261 taacccggca gcatctggta gctggaggta ccgtcatggg agttgagcag aatgatttca
     1321 gggacatgtt ctccgtttat ctctccggcc cgccgcagac gcagcatatg ttttgtgtat
     1381 ccccggcggc ccgggtcgcg cacacgggtc tggcaggcga agaatggctg aaagccttcc
     1441 cgctgcaggc tttccagtac ggtgatggtg ggaatgtacg catatcgttt actgcgggaa
     1501 gtatgccggt cttcaccgaa aatactggga acatagtgca tcagttcttc gtgtgtcagc
     1561 ggacggtcac ggcgtatctg gttcgtataa ccaaaacgac tggctagtcg cataatttgc
     1621 tccttatcgg tggttaagat ttactggtgt aataaatgaa aaagccacgt ctcccggaga
     1681 agacgcggcc tgacagatga aatgaatgac gtttattgtc tgagaagccc ttaactggcg
     1741 agctgagtat taagctgtgt tccggcatca ccagcgcaac tgaccttcag cattacggat
     1801 aaccagccgg gaatatgttc cctggtcatc ttcagtaaac acattgcggt aagctgtttt
     1861 gacggcaaca gcctgttcgc gtgagaaagg gccttcgggc aataaacgtg atgtacaacc
     1921 cggcatatct gttgctccct gaaagtaaaa agccccggtc atgatgaccg gggcctgaag
     1981 gagagtgacc tgattatcag aaagtcacat tcagcgtggc ctgaccgtta taaccttcag
     2041 cgctgctgcc gctgacgctg tgggcataac cggcctgaac gcccagggtg atattttccc
     2101 ggacacgggc ttccagtccg gcctgcaggt ccagtgacgt gccattccgg gacggtgaga
     2161 acgtcatgtt actgccggcg gcggctgtac ccatgctcat gtcaccccgg gagctgaaag
     2221 tgcggataac agaaggctgt acccaccagt tcaccggcag ttcactcaca cggtgttttg
     2281 tactgtcgcg cagagtgtca cgggatgagg tgccttcgcc aaaggtcata tcgttgtgac
     2341 tgcccagacg gaagccggca cgcacatgtt gtgtactgcc atgcccgaac ttcacataac
     2401 cggcgttatc ctggccgtca tccagggaga gcccctgcca ggtgtactgc agttgtggct
     2461 ccagcatcag gttgtcagtg atactgaagg gcagaccggt ttccagtgag cccagccagc
     2521 cccagccccg ggcgcggaag tcgttattgt ccgatgacgc tttcatgctg tggcgggttc
     2581 cctgtgccac aatgtcagcc cacaggccgg aggacgtgtg tgtcagattc aggtatccgc
     2641 ccaggctgcc ggcatcatcc cggaccgtgc cggcgcggga accgtcatca tccttaacat
     2701 caacggaaga atggcctgcg gcaccataca cccctgtcgt cagagacata ccggcaacct
     2761 ctgttctgag caggtcaccc tccagacgga cgaagccata gctgccgctg ctttccggcg
     2821 tggctccacg ggcaataccg ccgttgttat cgtgaccgag atgaccgccc tgaatgctga
     2881 gacggacgct gttattttca ccgtttacac cggtctgatg gctgcgggag cctgccagaa
     2941 tccggtcata gtccattgcc tgtgtcagca tggatgtata cagggggact tcagcacgat
     3001 aagcattttc actgcgcagg taccagtctt catcgctgtc acggttcagg gtgtagttaa
     3061 aggcgccggc ctgaagcggg cgactcaggg caaacgcacc ttcttctgtg gtggcgccat
     3121 tctgtgcatc cacaacccgg ataccctgtc cggaggttgc caccccgagg ttactgtttc
     3181 cgacatttgt aaacgcaagc caggttttgc cggttgcctg accaccatta atcaccagct
     3241 ggtcagaggt attgctgcca tcaaggcgaa cacgcatatt gatggtgcca ccctgaccgg
     3301 tgaggttatt ggtggtcagt ttatggaacg ttaccgggga gtcgcctttt gcaacagcac
     3361 ggctcagcgc agcatccggt gtcgtctgat tatcaaagcg aatctcccct gcgttaacaa
     3421 tatcgccggt actgaccaca tcgccattca gtaccatgct ggcaccttta ctgagctgtg
     3481 ttctgccact cagacttccc ccggcagcca gcgtcagtgt tccacgatgc ccgacagtgg
     3541 tgttgctggc cagtcctccg gcattaaccg taaagctgcc gccattttcc agcagcagtc
     3601 cgctggcctg accggatgtg ccatcaatac tgaacttacc gctggcattg gtcccctcaa
     3661 cagtggcacc actgtctgca atcagggcac taccggatgt catggtgaca tctgttgcct
     3721 taccaccggc agacactgcc agggttccgc cgtcatccac cagtgttttc caggctgaat
     3781 ggccctccag tacatccagg cgaccaccgg actccagaac aacaccgtca gcattaccgt
     3841 tttccacagt gaaattgccc agacggttgc tgccggtgac ggttgccgcc gtactggtga
     3901 ccagtgcgcc tccctgcttc agggtgacat tcgtggctgt accaccggcg ttcacctgca
     3961 gtttgccttt ctggttaacg gtggtgaaat ccgccagacc accttccttg acaatctgcc
     4021 agccgtcact gtttacaacc gtgtcagagg ctgtgcctcc gttgtgcaca tactggtaac
     4081 cgccattcag tgtggtatcc agcgcatgcc cgtgtaccgt ctggtcgccg ccggcataaa
     4141 ccacagtggt atttgctgtt ccttcaacag ccacaatctg acgaccattt ttattgatgg
     4201 tggtacgtac ggcatttccg cgaacaaact gcccggtatc accattttct gcatctggtc
     4261 ccccttccgc gccggtattc acaaccgtgt cggttgccac tgcgccggat ttgatggcct
     4321 gccagccctt ctcattaatg acggtacccg ttgcaatccc gccttcatgt acccactgct
     4381 caccgccgtt cagagtggtg ttcactgcct gcccctgaag gctctgtccg cctccggcac
     4441 tgataaccgt gtctgaaacg cttcctccgg cattcactct ctgaagacca ccaccggtga
     4501 cagtagtgtt gttggcgata ccgccatttt gtatccattg tccgccggta ttggcctcgt
     4561 tatccggccc atactccagc ccggtactga tggtcattcc gttggccgta ccgaagacaa
     4621 tctggttgtc atgatttgtc agtgttccgt cgttcacggt ttctcccgcc tgtacaaccg
     4681 tgtcagcagc cagtgccggg actgatgtga cagcagcaag agacagcgca accgccacac
     4741 cggcgcgttt tccccgtgag cgggccagtt cggaggccac caccagggtg cccgtaatgt
     4801 gattccatac cagcctgtag ctggtgttca gatgtcgttt catcagcttt tccttacaga
     4861 gggtgaataa aaaagccggt acccacaaat gtggataccg gcaggtacaa aacagcatgg
     4921 tcagataaag tggtttttcc cggacataaa tgcttcccct ctctcatccg ccagagaagt
     4981 atcagtccgt tgtgtgcaat tccgttctgc atgatgaaga gattcagctg ccttttcgca
     5041 ggccattaac cactataaac gatcgatagc aacgatcgat acctgtttta tcgatcgttt
     5101 tattctattg attacaaggc ggtcacgcaa gagaaacagg agggggatga ggggtttgtg
     5161 tcatattttc agttagttaa cgtaatgtaa tcagacattt ccctggcaga ctgttcagaa
     5221 gaaaatccag ttccatacag cgcgggcaac aga
//
LOCUS       DAPOAV010000173         5111 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.174, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000173 DAPOAV010000000
VERSION     DAPOAV010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5111
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.174"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..312
                     /locus_tag="RN951_004329"
     CDS             <1..312
                     /locus_tag="RN951_004329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDX2529221.1"
                     /translation="HYLDYIIDNNKNLIPIQEVMPIIGWNELEKISLEYITGKVNAIV
                     SKLIQENQLKAYDDDVLKNLLNGWFMHIAIHAKNLKELADKKGQFIAIYRGFLLSLKD
                     K"
     gene            complement(425..1630)
                     /gene="tet(B)"
                     /locus_tag="RN951_004330"
     CDS             complement(425..1630)
                     /gene="tet(B)"
                     /locus_tag="RN951_004330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001089064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(B)"
                     /protein_id="HDX2529222.1"
                     /translation="MNSSTKIALVITLLDAMGIGLIMPVLPTLLREFIASEDIANHFG
                     VLLALYALMQVIFAPWLGKMSDRFGRRPVLLLSLIGASLDYLLLAFSSALWMLYLGRL
                     LSGITGATGAVAASVIADTTSASQRVKWFGWLGASFGLGLIAGPIIGGFAGEISPHSP
                     FFIAALLNIVAFLVVMFWFRETKNTRDNTDTEVGVETQSNSVYITLFKTMPILLIIYF
                     SAQLIGQIPATVWVLFTENRFGWNSMMVGFSLAGLGLLHSVFQAFVAGRIATKWGEKT
                     AVLLGFIADSSAFAFLAFISEGWLVFPVLILLAGGGIALPALQGVMSIQTKSHQQGAL
                     QGLLVSLTNATGVIGPLLFAVIYNHSLPIWDGWIWIIGLAFYCIIILLSMTFMLTPQA
                     QGSKQETSA"
     gene            1712..2335
                     /gene="tetR(B)"
                     /locus_tag="RN951_004331"
     CDS             1712..2335
                     /gene="tetR(B)"
                     /locus_tag="RN951_004331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional
                     repressor TetR(B)"
                     /protein_id="HDX2529223.1"
                     /translation="MSRLDKSKVINSALELLNEVGIEGLTTRKLAQKLGVEQPTLYWH
                     VKNKRALLDALAIEMLDRHHTHFCPLEGESWQDFLRNNAKSFRCALLSHRDGAKVHLG
                     TRPTEKQYETLENQLAFLCQQGFSLENALYALSAVGHFTLGCVLEDQEHQVAKEERET
                     PTTDSMPPLLRQAIELFDHQGAEPAFLFGLELIICGLEKQLKCESGS"
     gene            complement(2313..2633)
                     /locus_tag="RN951_004332"
                     /pseudo
     CDS             complement(2313..2633)
                     /locus_tag="RN951_004332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
     gene            2702..3682
                     /locus_tag="RN951_004333"
     CDS             2702..3682
                     /locus_tag="RN951_004333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000019445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element ISKpn26 family transposase"
                     /protein_id="HDX2529224.1"
                     /translation="MSHQLTFADSEFSTKRRQTRKEIFLSRMEQILPWQNMVEVIEPF
                     YPKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRLFARLSLDSALPDR
                     TTIMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQR
                     DPEMHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVS
                     ADAGYQGAPQREELAEVDVDWLIAERPGKVKTLKQHPRKNKTAINIEYMKASIRARVE
                     HPFRIIKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRVDQMIRQWERSQ"
     gene            complement(3822..4199)
                     /locus_tag="RN951_004334"
                     /pseudo
     CDS             complement(3822..4199)
                     /locus_tag="RN951_004334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(4207..4593)
                     /locus_tag="RN951_004335"
     CDS             complement(4207..4593)
                     /locus_tag="RN951_004335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid-binding protein"
                     /protein_id="HDX2529225.1"
                     /translation="MFDVHVVLDNQIGQLALLGKTLGNKGIGLEGGGIFTVGDECHAH
                     FLVEQGKEAKIALEQAGLLVLAIRTPLIRKLKQEKPGELGEIARVLAENNINILVQYS
                     DHANQLILITDNDSMAASVTLPWAIK"
     gene            complement(4586..4849)
                     /locus_tag="RN951_004336"
     CDS             complement(4586..4849)
                     /locus_tag="RN951_004336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDX2529226.1"
                     /translation="MSWSHYRPLLSHVAGFISIERFQSLATEGKMLSLSWWENEYAVL
                     QWKNHVLHAKAQQEGRESIFDFYKISIAHITREYSFKKDKDNV"
     gene            complement(4846..>5111)
                     /locus_tag="RN951_004337"
     CDS             complement(4846..>5111)
                     /locus_tag="RN951_004337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="HDX2529227.1"
                     /translation="ATLGRLMSLLSPFDVVIWMTDGWPLYESRLKGKLHVISKRYTQR
                     IERHNLNLRQHLARLGRKSLSFSKSVELHDKVIGHYLNIKHYQ"
BASE COUNT         1564 a         1198 c         1043 g         1306 t
ORIGIN      
        1 cattatcttg attatattat tgataataat aaaaacctta tccctatcca agaagtgatg
       61 cctatcattg gttggaatga acttgaaaaa attagccttg aatacattac tggtaaggta
      121 aacgccattg tcagcaaatt gatccaagag aaccaactta aagcttatga tgatgatgtg
      181 cttaaaaact tactcaatgg ctggtttatg catatcgcaa tacatgcgaa aaacctaaaa
      241 gagcttgccg ataaaaaagg ccaatttatt gctatttacc gcggcttttt attgagcttg
      301 aaagataaat aaaatagata ggttttattt gaagctaaat cttctttatc gtaaaaaatg
      361 ccctcttggg ttatcaagag ggtcattata tttcgcggaa taacatcatt tggtgacgaa
      421 ataactaagc acttgtctcc tgtttactcc cctgagcttg aggggttaac atgaaggtca
      481 tcgatagcag gataataata cagtaaaacg ctaaaccaat aatccaaatc cagccatccc
      541 aaattggtag tgaatgatta taaataacag caaacagtaa tgggccaata acaccggttg
      601 cattggtaag gctcaccaat aatccctgta aagcaccttg ctgatgactc tttgtttgga
      661 tagacatcac tccctgtaat gcaggtaaag cgatcccacc accagccaat aaaattaaaa
      721 cagggaaaac taaccaacct tcagatataa acgctaaaaa ggcaaatgca ctactatctg
      781 caataaatcc gagcagtact gccgtttttt cgccccattt agtggctatt cttcctgcca
      841 caaaggcttg gaatactgag tgtaaaagac caagacccgc taatgaaaag ccaaccatca
      901 tgctattcca tccaaaacga ttttcggtaa atagcaccca caccgttgcg ggaatttggc
      961 ctatcaattg cgctgaaaaa taaataatca acaaaatggg catcgtttta aataaagtga
     1021 tgtataccga attcgattgc gtctcaaccc ctacttcggt atctgtatta tcacgtgtat
     1081 ttttggtttc acggaaccaa aacataacca caaggaaagc gacaatattt agcaacgcag
     1141 cgataaaaaa gggactatgc ggtgaaatct ctcctgcaaa accaccaata ataggccccg
     1201 ctattaaacc aagcccaaaa cttgccccta accaaccgaa ccacttcacg cgttgagaag
     1261 ctgaggtggt atcggcaatg accgatgccg cgacagcccc agtagctcct gtgatccctg
     1321 aaagcaaacg gcctaaatac agcatccaaa gcgcacttga aaaagccagc aataagtaat
     1381 ccagcgatgc gcctattaat gacaacaaca gcactgggcg ccgaccaaat cggtcagaca
     1441 tttttccaag ccaaggagca aagataacct gcattaacgc ataaagtgca agcaatacgc
     1501 caaagtggtt agcgatatct tccgaagcaa taaattcacg taataacgtt ggcaagactg
     1561 gcatgataag gccaatcccc atggcatcga gtaacgtaat taccaatgcg atctttgtcg
     1621 aactattcat ttcacttttc tctatcactg atagggagtg gtaaaataac tctatcaatg
     1681 atagagtgtc aacaaaaatt aggaattaat gatgtctaga ttagataaaa gtaaagtgat
     1741 taacagcgca ttagagctgc ttaatgaggt cggaatcgaa ggtttaacaa cccgtaaact
     1801 cgcccagaag ctaggtgtag agcagcctac attgtattgg catgtaaaaa ataagcgggc
     1861 tttgctcgac gccttagcca ttgagatgtt agataggcac catactcact tttgcccttt
     1921 agaaggggaa agctggcaag attttttacg taataacgct aaaagtttta gatgtgcttt
     1981 actaagtcat cgcgatggag caaaagtaca tttaggtaca cggcctacag aaaaacagta
     2041 tgaaactctc gaaaatcaat tagccttttt atgccaacaa ggtttttcac tagagaatgc
     2101 attatatgca ctcagcgctg tggggcattt tactttaggt tgcgtattgg aagatcaaga
     2161 gcatcaagtc gctaaagaag aaagggaaac acctactact gatagtatgc cgccattatt
     2221 acgacaagct atcgaattat ttgatcacca aggtgcagag ccagccttct tattcggcct
     2281 tgaattgatc atatgcggat tagaaaaaca acttaaatgt gaaagtgggt cttaaaagca
     2341 gcataacctt tttccgtgat ggtaacttca cggtaaccaa gatgtcgagt taaccaccct
     2401 ttagattcat aaagcgaaaa taatgcggct ccaacgtacc cacctaaatg gaaacggcgt
     2461 tcactccaat ctaaacacgc acaacagatt ttacgtgaat gtttggaagg aacgtcaatt
     2521 cccatttcat gaaaatattg aataccactt aatgtgatca ttgaaccatt ttcagtgatc
     2581 cattgctgtt gacaaaggga atcatagatc ttaacggcaa cttcgccagc taaggaaggt
     2641 gcgaacaagt tcctgatatg agatcatcat attcatccgg agcgcatccc agagggacat
     2701 catgagccat caactcacct tcgccgatag tgaattcagc actaagcgcc gtcagacccg
     2761 aaaagagatt ttcctctccc gcatggagca gattctgcca tggcaaaaca tggtggaagt
     2821 catcgagccg ttttatccca aggcgggcaa tggccgacgg ccctatccgc tggagaccat
     2881 gctgcgtatt cactgcatgc agcattggta caacctgagc gacggtgcca tggaagatgc
     2941 cctgtacgaa atcgcctcca tgcgcctgtt tgcccgatta tccctggata gcgccctgcc
     3001 ggatcgcacc accatcatga atttccgcca cctgctcgag cagcatcaac tggcccgtca
     3061 attgttcaag accatcaatc gctggctggc cgaagcaggc gtcatgatga cccaaggcac
     3121 tttggtggat gccaccatca ttgaggcacc cagctctacc aagaacaaag agcagcaacg
     3181 cgatccggag atgcatcaga ccaagaaagg caatcagtgg cactttggca tgaaggccca
     3241 cattggtgtc gatgccaaga gtggcctgac ccacagccta gtcaccaccg cggccaacga
     3301 gcatgacctc aatcagctgg gtaatctgct tcatggagag gagcaatttg tctcagccga
     3361 tgccggctac caaggagcgc cacagcgcga ggagctggcc gaggtggatg tggactggct
     3421 gatcgccgag cgtcccggca aggtaaaaac cttgaagcag catccgcgca agaacaaaac
     3481 ggccatcaac atcgaataca tgaaagccag catccgtgcc agggtggagc acccgtttcg
     3541 catcatcaag cggcagttcg gcttcgtgaa agccagatac aaggggctgc tgaaaaacga
     3601 taaccaactg gcgatgttat tcaccctggc caacctgttt cgggtggacc aaatgatacg
     3661 tcagtgggag agatctcagt aaaaaccgga aataacgcca gaaatggtgg aaaaaatagc
     3721 ctaaataggc tgattcgatg tgtttgcggg aaaaaaatcg gcccagatcc gagaaatttt
     3781 aatcagcgag tcagcttggg aagaaatgac ctgcttattc gcaccttccc taaatgatca
     3841 tagcaagtac gtgcttttcg taaatgcact ggcgtggaaa ctttggcatg tacgccatgg
     3901 tttaaggaga tccccatcat actttccatc aattcagcaa tatcttttcc tgctagccga
     3961 aaataacgat gcttgccttg agctactact gtgattagct ggcaatctaa taatttagat
     4021 aaatgactgc tcgccgttga agctgatata ttcgccacag aacttagctc agtggccgtc
     4081 caagctcgcc catccatcaa agcattgagt attttaactc gtgaaatgtc agacatagcc
     4141 gcccctatcg cggctattga ggactcaaag gtaacctctt ttcgtattaa attagccatc
     4201 gcaagttcac tttattgccc aagggagcgt aacagatgca gccatactat cattgtccgt
     4261 tattaatatc agttggttag catggtcact gtattgcact aaaatattaa tgttattctc
     4321 cgccaatact cgtgctattt cgccaagttc ccccggtttt tcctgtttta acttacgaat
     4381 taatggtgtc cggatcgcaa gtactaacag tccagcttgc tctagcgcta ttttagcttc
     4441 ctttccttgt tcaacaagaa aatgagcatg gcattcatca ccaaccgtaa atatccctcc
     4501 cccttccaat ccaatacctt tattacctaa tgtttttcct agtaatgcta attgtcctat
     4561 ttgattatct aaaacaacgt gaacatcaaa cattatcctt gtccttttta aatgaatatt
     4621 cgcgagtaat atgagcaata ctaattttgt aaaaatcaaa tattgactct cgcccttctt
     4681 gttgagcttt cgcatgtaaa acatgatttt tccattgcag aactgcgtat tcgttttccc
     4741 accaagatag cgataacatt tttccttctg tagctagact ttgaaaacgt tcaattgaaa
     4801 taaaaccagc tacatgactt aatagtggtc ggtaatgact ccaacttatt gatagtgttt
     4861 tatgttcaga taatgcccga tgactttgtc atgcagctcc accgattttg agaacgacag
     4921 cgacttccgt cccagccgtg ccaggtgctg cctcagattc aggttatgcc gctcaattcg
     4981 ctgcgtatat cgcttgctga ttacgtgcag ctttcccttc aggcgggatt catacagcgg
     5041 ccagccatcc gtcatccata tcaccacgtc aaagggtgac agcaggctca taagacgccc
     5101 cagcgtcgcc a
//
LOCUS       DAPOAV010000174         5084 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.175, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000174 DAPOAV010000000
VERSION     DAPOAV010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5084
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.175"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            136..1494
                     /gene="mltD"
                     /locus_tag="RN951_004338"
     CDS             136..1494
                     /gene="mltD"
                     /locus_tag="RN951_004338"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase D"
                     /protein_id="HDX2529228.1"
                     /translation="MKAKAILLASVLLVGCQSTGNVQQHAQSLSAAGQGEAAKFTSQA
                     RWMDDGTSIAPDGDLWAFIGDELKMGIPENDRIREQKQKYLRNKSYLHDVTLRAEPYM
                     YWIAGQVKKRNMPMELVLLPIVESAFDPHATSGANAAGIWQIIPSTGRNYGLKQTRNY
                     DARRDVVASTTAALNMMQRLNKMFDGDWLLTVAAYNSGEGRVMKAIKTNKARGKSTDF
                     WSLPLPQETKQYVPKMLALSDILKNSKRYGVRLPTTDESRALARVHLSSPVEMAKVAD
                     MAGISVSKLKTFNAGVKGSTLGASGPQYVMVPKKHADQLRESLASGEIAAVQSTLVAD
                     NTPLNSRVYTVRSGDTLSSIASRLGVSTKDLQQWNKLRGSKLKPGQSLTIGAGSSAQR
                     LANNSDSITYRVRKGDSLSSIAKRHGVNIKDVMRWNSDTANLQPGDKLTLFVKNNNMP
                     DS"
     gene            complement(1542..2138)
                     /locus_tag="RN951_004339"
                     /pseudo
     CDS             complement(1542..2138)
                     /locus_tag="RN951_004339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308233.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            complement(2169..2969)
                     /locus_tag="RN951_004340"
     CDS             complement(2169..2969)
                     /locus_tag="RN951_004340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDX2529229.1"
                     /translation="MRKNTYAMRYVAGQPAERILPPGSFASIGQALPPGEPLSTEERI
                     RILVWNIYKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFV
                     LPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNF
                     SLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRRRMNALYRFAREMSLRQVRFTD
                     DQRRRAFGRPLDFVFYRGLNVSEASVLVTRASDHNPLLVEFSPGKPDK"
     gene            3210..4124
                     /locus_tag="RN951_004341"
     CDS             3210..4124
                     /locus_tag="RN951_004341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDX2529230.1"
                     /translation="MKATSEELAIFVSVVESGSFSRAAEQLGQANSAVSRAVKKLEMK
                     LGVSLLNRTTRQLSLTEEGERYFRRVQSILQEMAAAESEIMETRNTPRGLLRIDAATP
                     VVLHFLMPLIKPFRERYPEVTLSLVSSETIINLIERKVDVAIRAGTLTDSSLRARPLF
                     NSYRKIIASPDYISRYGKPETIDDLKQHICLGFTEPASLNTWPIARSDGQLHEVKYGL
                     SSNSGETLKQLCLSGNGIACLSDYMIDKEIARGELVELMADKVLPVEMPFSAVYYSDR
                     AVSTRIRAFIDFLSEHVKTAPGGAVREA"
     gene            complement(4121..4924)
                     /gene="dkgB"
                     /locus_tag="RN951_004342"
     CDS             complement(4121..4924)
                     /gene="dkgB"
                     /locus_tag="RN951_004342"
                     /EC_number="1.1.1.346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgB"
                     /protein_id="HDX2529231.1"
                     /translation="MAIPAFGLGTFRLKDDVVISSVITALELGYRAIDTAQIYDNEAA
                     VGQAIAESGVPRHELYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPN
                     DEVSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQ
                     NRKVVAWAKQHGIHITSYMTLAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSV
                     IPSSTKRKNLESNLKAQNLQLDAEDKKAIAALDCNDRLVSPEGLAPEWD"
BASE COUNT         1347 a         1223 c         1261 g         1253 t
ORIGIN      
        1 aacattattg caacaacctg aagagcgttt tgcatggtta aggtcaaaga aagataggtt
       61 ctgataaaac tttcttgtca tcggctccgt tcgccgttat gatcggtcgt cttttaagca
      121 actattgaca cacacatgaa ggcaaaagcg atattactcg cctctgtcct gctcgtgggt
      181 tgccagagta ccggcaacgt tcaacagcac gcacagagcc tttctgcagc tggtcaaggg
      241 gaagcagcaa agtttacaag tcaggcacga tggatggacg atgggacgtc tatcgcgcca
      301 gatggtgact tgtgggcttt cattggcgac gagctaaaga tgggaattcc ggaaaatgac
      361 cggattcgcg aacagaaaca gaaatattta cgcaataaga gctatctcca cgatgtaact
      421 ttacgggcag agccgtatat gtactggata gcagggcaag ttaaaaaacg taacatgcct
      481 atggaactgg tactactacc catagtggag agcgcttttg atcctcacgc aacgtctggc
      541 gccaatgccg caggcatctg gcagatcatt ccgagcacgg ggcgcaatta tggtttgaaa
      601 cagacccgca attatgacgc gcgtcgcgat gttgttgctt caacaactgc cgcgctgaat
      661 atgatgcagc gtctgaacaa aatgtttgac ggcgactggc ttctgaccgt agcggcttat
      721 aacagcggcg aaggtcgggt catgaaggca attaaaacga acaaagcgcg tgggaaatcc
      781 acggacttct ggtcgttacc gttgccgcag gaaacgaagc agtacgtgcc taaaatgctg
      841 gcattgagtg atattctcaa aaacagcaag cgttatggcg tacgtctgcc aacgaccgat
      901 gaaagccgtg ctctggcgcg tgtgcacctg agcagcccgg ttgaaatggc gaaggtagca
      961 gatatggcgg ggatttccgt cagcaagctg aagacattca acgctggcgt aaaaggctcc
     1021 acgctgggcg caagtggccc gcagtacgtg atggtgccaa agaagcatgc agatcaactg
     1081 cgtgaatctc tggcttcagg cgaaattgct gctgtacagt cgacgctggt tgccgacaat
     1141 acgccgctta acagccgtgt ttacaccgta cgctctggcg acacgctttc aagtatcgct
     1201 tcacgtctcg gcgtaagcac caaagatttg cagcagtgga acaaactgcg cggatctaag
     1261 ctgaagccag gccaaagttt gacgattggt gcaggcagta gcgcacagcg actggcaaac
     1321 aacagcgata gcattacgta tcgtgtgcgc aaaggcgatt cgctttcaag cattgctaaa
     1381 cgccacggcg tgaacatcaa agatgtgatg cgctggaaca gcgacactgc gaatctgcaa
     1441 ccaggcgata agctgacgtt gtttgtgaaa aacaacaaca tgccagattc ctgacaaacc
     1501 agataataaa aaggcaccga ttcccccggt gcctttttta tttatgccgc tttatgtgca
     1561 tctaccatga tgatatcact ggtgaaaaag ccatcattct gcaaggcaaa atacgttctc
     1621 acctctgtcg atgcgctctg ttggtaaatg cgaatagcgt ctactaacgc ttctggcgta
     1681 cgcattctcg cgacccatga agaaaattcc agcggtaact tatctgtaat taaattatca
     1741 actatcagat tggcttcatt gattaacgtc aaccactcac cgctggcgta gtttcgtacg
     1801 tgagaggtat cgcgtaatgc ttctaccgtc tgtaaccaga tgtcgcgcac tgggtgaccc
     1861 ggagacatta cgtccatcac aatcagccta ccgccaggtt tcaatatcct attcacttct
     1921 cgcagtgctg caccaacatc atgccagtga tgggcagaat aacggctgat aacaatatca
     1981 aatgcgttat cggcaaatgg cagactttcg gcatatccct ggcgggtggt gatatttttc
     2041 agttgccggg cttcggcagc ttgtgccacg acatccagca tgtgggcaga taagtcatac
     2101 gccaccaccg cgctcacgtt ttgcgcagcg ccaaacgttg gtctgccctg tggcagacct
     2161 gacatacctt atttatcagg cttgccggga ctgaattcaa cgagtagcgg attgtgatcg
     2221 gaagcgcgcg taaccagtac agaagcttca ctgacgttca gaccacggta gaaaacaaaa
     2281 tcgagcgggc gaccaaacgc ccgacggcgc tgatcatcgg taaaacgcac ctggcgcagc
     2341 gacatttccc gcgcaaagcg atataacgcg ttcatccttc tacggctcca ggcattgaaa
     2401 tctcccgcca taatgaccgg gccgctgtgg tgagctatct gatcgccaat aggaagtaac
     2461 tgcttactat agacatccac gcccagactg aagttgacgg cgtgtatatt aaccaccatc
     2521 aacaggcggg tgtcaggtaa tggatagacc gtcaccagtg ccgacttcgc cagacgcaaa
     2581 atgggttctc gttcacgtaa cgggcagcaa tacactggat gtgccgccga aagggtcatt
     2641 acgccagaag gatgttgtgg cagcacgaaa gcgggtacct gatcggcggc aagatagtta
     2701 gcggtcgcaa actgtactaa ctctggcgtt gtctgcgctt cctgcaataa caccagatgt
     2761 gcatctttgc cgtagttctt taataccgac aaccattcag cgcgttgctg tttgtatatg
     2821 ttccacacca ggatccgaat acgctcttcg gtacttaacg gttccccagg tggtaatgcc
     2881 tggccgatgc tcgcaaaaga ccccggcggt aagatccttt ccgcaggttg tccggcaaca
     2941 tagcgcatgg cataggtgtt ttttcgcact tttgactttg aaacctctat tacgtcaacc
     3001 cttccgcact cgggagggtt ctactgttat agggatttta gctcactctt tcaacgagca
     3061 attgtatatt gttatgtaag caagtgctta caccggtcag aattttgctc attatggaga
     3121 acattaaatc gcatgacata tcacgcatcc tgatggttta atgacaaata aattcaaaat
     3181 atctcttcta ttttgcaaca ggagcaaaaa tgaaagccac gtcagaagaa ctcgccattt
     3241 ttgtttcggt cgtcgaaagc ggcagcttta gccgggcagc ggaacaatta gggcaagcaa
     3301 actcagcggt aagccgggcg gtgaaaaagc tggagatgaa acttggcgtt agcctgctta
     3361 atcggaccac gcgacaactt agcctgacgg aagaaggcga gcgttatttt cgtcgcgtac
     3421 agtcaatttt gcaggagatg gcagcggcag aatcagaaat tatggagacg cgtaatacac
     3481 cgcgtggact gttacggatc gatgccgcaa ctccagtggt gctgcacttt ctgatgccgt
     3541 taattaagcc tttccgtgaa cgctatccgg aagtcacttt gtcgctagtc tcctccgaaa
     3601 cgattattaa tttgatcgaa agaaaagtgg atgtcgcgat acgcgctggt acgttaacgg
     3661 attccagctt acgtgccagg ccgttattta acagttatcg aaaaattatc gcctcccccg
     3721 attatatttc ccgctacggg aagccagaaa cgatcgacga tttaaagcaa catatttgcc
     3781 tgggattcac tgaacccgct tccctcaata cctggccgat agcccgtagc gatggacaat
     3841 tacatgaggt gaagtacggt ttgtcatcca atagtgggga aacactgaaa cagctttgcc
     3901 tgagtggcaa cgggattgcg tgtttgtccg actacatgat cgacaaagaa atcgctcgcg
     3961 gagaattggt ggagttaatg gcagataaag tgttgccagt ggaaatgcca ttcagtgccg
     4021 tctattacag cgaccgtgcg gtaagtacgc gcatccgggc ttttatcgat ttccttagcg
     4081 agcatgtaaa aacagctccc ggaggagctg tcagagaggc ttaatcccat tcaggagcca
     4141 gaccttccgg gctaaccagg cggtcgttgc aatccagtgc ggcgatcgct tttttatctt
     4201 cggcatcaag ctgtaaattt tgtgccttaa gattactttc caggttttta cgtttagtag
     4261 aagaaggaat tactgagtaa ccttccccca tagcccacgc cagaatcact tgtgccggag
     4321 tcgcattgtg tttagctgcg atacgagcaa taacctcatc tttcagggcc ttaccatacg
     4381 ccagcgtcat ataggaagta atatggatgc cgtgctgttt agcccaggca accactttac
     4441 ggttttgcag ataaggagag agttcaatct ggttagtagc gatgttttca gcaccaacag
     4501 cagcaatcgc tttttccatc aacgggatcg tgaagttgga aataccgatc tcacgcgtca
     4561 gcccttgttt tttggcttcc agcagcgcct gcataaactc ttcaacagag acttcatcgt
     4621 ttggtgacgg ccagtggatt agcgtcagat caacataatc ggtacgcaat ttttgcaggc
     4681 tctctttcag acttgggatc aatttgtctt tgctgagatt ttcaatccag attttagtgg
     4741 tgatgtagag ttcatgacgt ggcacgccac tttctgcaat cgcctgacct actgcggctt
     4801 cgttatcata gatttgtgcg gtatcaattg cgcgataacc aagttcaagc gccgttatca
     4861 cagatgaaat aacaacgtcg tctttcagac ggaaagtacc taaaccaaat gcagggatag
     4921 ccataatatg cctcttttaa tgctattttc gttaactgag gtgattatgg gcttcagact
     4981 gttgaggaaa aagagcgtaa aatgcagagg atttttgcga ttctggcaat aatagatata
     5041 cagacgaaaa aaaacctcga gcgttaactc gaggcttctt aata
//
LOCUS       DAPOAV010000175         5044 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.176, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000175 DAPOAV010000000
VERSION     DAPOAV010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5044
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.176"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..1184
                     /locus_tag="RN951_004343"
     CDS             <1..1184
                     /locus_tag="RN951_004343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026203.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529232.1"
                     /translation="AGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESP
                     ECKDYPSVISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLL
                     SDSPFYGLVLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNVGS
                     LPPLGLLVKNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALRAMNIAFG
                     ILFVTVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSVILNIF
                     AVMTAFFGVYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLN
                     APVLSFTSICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAF
                     S"
     gene            1212..2522
                     /locus_tag="RN951_004344"
     CDS             1212..2522
                     /locus_tag="RN951_004344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HDX2529233.1"
                     /translation="MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAEL
                     EGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQ
                     AIADAKALLAAGKVSVKIQEPCDEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHDG
                     VVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEG
                     LSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQ
                     GITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAA
                     GMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDT
                     AVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR"
     gene            complement(2656..2820)
                     /locus_tag="RN951_004345"
     CDS             complement(2656..2820)
                     /locus_tag="RN951_004345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529234.1"
                     /translation="MSKKLAKKRQPVKPVVAKEPARTAKNFGYEEMLSELEAIVADAE
                     TRLAEDEATA"
     gene            complement(2843..3544)
                     /locus_tag="RN951_004346"
     CDS             complement(2843..3544)
                     /locus_tag="RN951_004346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pirin family protein"
                     /protein_id="HDX2529235.1"
                     /translation="MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLN
                     QEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEGNHVQASAGEALLLSTQPGVSYS
                     EHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMGKQQLIASPEGAMGSLQLRQQVW
                     LHHIVLDKGESANFQLHGPRAYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITL
                     VADSPLRALLIDLPV"
     gene            3649..4545
                     /gene="yhaJ"
                     /locus_tag="RN951_004347"
     CDS             3649..4545
                     /gene="yhaJ"
                     /locus_tag="RN951_004347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YhaJ"
                     /protein_id="HDX2529236.1"
                     /translation="MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQK
                     LEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIV
                     TEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSS
                     EINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLD
                     KQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWR
                     RDSMGEAKSWCLREIPKLFNGK"
     gene            complement(4596..4952)
                     /locus_tag="RN951_004348"
     CDS             complement(4596..4952)
                     /locus_tag="RN951_004348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HDX2529237.1"
                     /translation="MQWYLSVLKNYVGFSGRTRRKEYWMFTLINAIVGAIINVIQLIL
                     GLELPYLSMLYLLATFLPVLALAIRRLHDTDRSGAWALLFFVPFIGWLVLLVFFCTEG
                     TSGSNRYGNDPKFGSN"
BASE COUNT         1149 a         1197 c         1432 g         1266 t
ORIGIN      
        1 gcgcggggat tgtttttctc ccggtgcagg tcggtttgat gggattgtgg gtatttttgc
       61 tctcatcggt gattggttac ccggcaatgt atctgtttca gcgattgttt attaatacgc
      121 tggcagaatc accagaatgt aaagattacc cgagcgtcat tagcggttat ttaggtaaaa
      181 actggggcat cctgttaggt gcgctctatt tcgtaatgct ggtgatttgg atgttcgtct
      241 attccaccgc catcaccaac gatagtgctt cctacctgca taccttcggc gtgacggaag
      301 ggttgctgtc agacagtccc ttttatggtc tggtactgat ttgcattctg gtggcgatct
      361 cctcacgcgg cgagaaattg ttattcaaaa tttcgaccgg catggtgctg accaagctgc
      421 tggtggtcgc ggcgctgggc gtgtcgatgg tgggaatgtg gcatctgtat aacgtcggtt
      481 cgctaccgcc gctggggctg ctggtgaaaa acgccattat tacgctgccg tttaccctga
      541 cgtcgattct gtttatccag acgttaagtc cgatggtgat ctcttatcgc tcgcgggaaa
      601 aatcaattga agtggcgcgg cataaagcat tgcgggcaat gaatatcgcg tttggcattt
      661 tgtttgtcac cgtctttttc tacgccgtgt cgttcacgct ggcgatggga catgacgaag
      721 cggtaaaagc ctatgagcag aatatttccg cgctggcgat tgccgcacag tttattagcg
      781 gtgacggcgc agcgtgggtg aaagtggtca gcgtcattct caatatcttt gctgtcatga
      841 ctgcattctt tggcgtctat ttaggctttc gcgaagcaac gcaagggatc gtaatgaaca
      901 tcctgcgtcg caagatgcct gccgagaaga ttaacgaaaa tctcgttcag cgcggcatca
      961 tgattttcgc cattttgctg gcctggagcg ccatcgtact gaacgcaccg gtgttgagct
     1021 tcacctctat ctgtagcccg attttcggca tggtagggtg cctgatcccg gcgtggctgg
     1081 tttacaaagt accagcattg cacaaataca aagggatgtc tctgtacctg attatcgtca
     1141 ctggtttgtt gctgtgtgtt tctccgttcc tggcattttc ttgatttacc tgaaatttta
     1201 aggtttttaa tatgtttgat tcgactttaa atccgttatg gcagcgttac atcctcgccg
     1261 ttcaggagga agtaaaaccg gcgctgggat gtactgaacc gatttcactg gcgctggcgg
     1321 cggcggttgc tgcggcagaa ctggaaggtc cggttgaacg tgtagaagcc tgggtttcgc
     1381 caaatctgat gaagaacggt ctgggcgtca ccgttcccgg cacgggaatg gtggggctgc
     1441 cgattgcggc ggcgctgggg gcgttaggtg gaaatgccaa cgccgggctg gaagtgctga
     1501 aagacgcaac agcgcaggca attgccgatg ccaaagcact gctggcggcg gggaaagtct
     1561 ccgttaagat ccaggaacct tgcgatgaaa tcctcttctc acgcgccaaa gtctggaacg
     1621 gtgagaagtg ggcgtgtgtc accatcgtcg gcgggcatac caacattgtg catatcgaga
     1681 cgcacgatgg tgtggtgttt acccagcagg cgtgtgtggc agagggcgag caagagtctc
     1741 cgctgacggt gctttccaga acgacgctgg ctgagatcct gaagttcgtc aatgaagtcc
     1801 cgtttgcggc gatccgcttt attctcgatt ccgcgaagct aaattgtgcg ttatcgcagg
     1861 aaggtttgag cggtaagtgg gggctgcata ttggcgcgac gctggaaaaa cagtgcgagc
     1921 gcggtttgct ggcgaaagat ctctcttcat ccattgtgat tcgtaccagc gcggcatccg
     1981 atgcgcgtat gggcggcgct acgcttccgg ctatgagtaa ctccggctcg ggtaaccagg
     2041 ggattaccgc aacaatgcct gtggtggtgg tagcagaaca cttcggagcg gatgatgaac
     2101 ggctggcgcg tgcgctgatg ctttcgcatt tgagcgcaat ttacatccat aaccagttac
     2161 cgcgtttgtc tgcgctgtgt gccgcaacga ccgcagcaat gggggccgcc gccgggatgg
     2221 catggctggt ggatgggcgt tatgaaacca tctcgatggc gatcagcagt atgatcggcg
     2281 atgtcagcgg catgatttgc gatggtgcgt cgaacagctg cgcgatgaag gtttcgacca
     2341 gtgcttcggc tgcgtggaaa gcggtgttaa tggcgctgga tgataccgcc gtgaccggca
     2401 atgaagggat tgtggcgcat gatgttgagc agtcgattgc caacctgtgt gcgttagcaa
     2461 gccattcgat gcagcaaacg gatcggcaga ttatcgagat tatggcgagc aaggccagat
     2521 aaacgccagg ttttggggat cgtgccggat gcgatgctgg cgcatcttgt ccggcctacg
     2581 ggttgtttaa ttcgttaatg ttgttggatt ttgtaggccg gataaggcgt tttcgccgca
     2641 tccggcaacc tgtctttacg cggtagcttc atcctcggct aaacgcgttt cagcatccgc
     2701 gacgatagct tccagctcgc tcaacatctc ttcatagcca aaatttttgg cggtgcgagc
     2761 aggttctttc gccaccacgg gcttcaccgg ctggcgcttt ttggccaatt ttttactcat
     2821 catcatctcc ctgtaaaaac aactagacag gcaaatctat cagcaaagcg cgcagtgggg
     2881 aatcggcaac cagcgtaatg ttagcctcgt cacgaataaa cgccccatca ccgcaggtca
     2941 gcgccgcttt ctcttcatga tgcgtaagcg catgaaattt cccgtgaatc gattgcaaat
     3001 acgcgcgtgg cccatgcaac tggaaattcg cactttcgcc tttgtcgagc acgatatggt
     3061 gcagccacac ttgctggcgt aattgcaggc ttcccatcgc accctctggc gaggcgatta
     3121 attgctgctt gcccatatta agcgccagct tttgaatcag cggattctct cgctgcgggc
     3181 aggcgtccag ccaaagctgc attcgcgtta acggtttgtc tttgctgaga ttgtgttcgc
     3241 tatagctgac acccggctgg gtagagagca gcaacgcctc tccggcgctg gcctgaacat
     3301 gattgccttc gctatcgcga tactctgctt ctccatccag aatcacattt aaaatatcga
     3361 ctttgggata ggttcgcggc tgaaaggcgg cacctggggc cagcacttcc tggttaagca
     3421 cacgcaggga ggcatagcct aacaatttcg ggtcgaagta gtgtccaaag gaaaaagtat
     3481 accgggcctg caaccatccg tagtctgctt gtccacactg cctggcagtt cgggtagtaa
     3541 tcataattct tgacctctct ttacttcctt ttatggtaag gggctggacg ctacattgtt
     3601 agccagatat tctgcccggt atgttcaaat ttcctgaatg agaacgaaat ggccaaagaa
     3661 agggcattaa cgctggaagc actacgggtt atggatgcga tcgatcgccg gggcagtttt
     3721 gcggcggcgg cggatgagct gggacgcgtg ccttccgcac ttagctacac catgcaaaaa
     3781 ctggaagaag agctggatgt ggtgctgttt gaccgctcgg gccatcgtac caaattcacc
     3841 aatgtcggga ggatgttgtt ggagcgaggg cgcgttttgc tggaagccgc agataaactg
     3901 actactgatg cggaagctct cgcgcgcggt tgggaaacgc atctcaccat tgtgaccgaa
     3961 gcgctggtac cgacacctgc ctttttcccg ttaatcgaca aactggcggc aaaagccaat
     4021 acccaactgg caatcatcac agaagtgctg gcgggggcgt gggaacggct ggagcagggg
     4081 cgggcggata ttgttatcgc gccggatatg cattttcgtt cctcgtcgga gatcaactcg
     4141 cgcaagctct atacgttaat gaacgtctac gttgccgcgc ctgatcaccc gattcatcag
     4201 gagccggaac cgttatctga agtgacgcgt gtgaaatatc gtggaattgc ggtggcggat
     4261 accgctcgtg agcgcccggt gttgaccgta cagctgctgg acaaacagcc gcgcttaacg
     4321 gtgagcacga ttgaagataa acgtcaggca ttactggcgg ggcttggcgt ggcgacgatg
     4381 ccgtatccta tggtcgaaaa agatattgcg gaagggcggt tgcgtgtcgt cagcccggaa
     4441 tcgaccagcg agatcgatat tattatggcc tggcgtcgtg acagtatggg ggaagcgaaa
     4501 tcctggtgtc tgcgggaaat tcccaaactt tttaacggaa aataatattt attattgtta
     4561 ataaaaaggg gcgaaatatc gccccaattc taagattaat ttgaaccaaa cttcggatcg
     4621 tttccgtaac gattgctgcc agaagtacct tctgtgcaga aaaaaaccag aagcacgagc
     4681 cagccaataa acggaacaaa aaagagcaag gcccaggcac ctgaacggtc ggtatcgtgt
     4741 aagcgacgga tagcaagcgc aaggacggga aggaaggttg ccagcaaata aagcatagac
     4801 agatatggaa gctccagacc taaaatcaat tgaatgacat tgataatagc gccgacgatg
     4861 gcgttaatca gagtaaacat ccagtactct ttacgacgtg tgcgaccaga gaaaccaaca
     4921 taatttttta atacggacaa ataccactgc ataaaaacat ccctttaatt aaaagtgacg
     4981 aaagtctatt ccgggtattg tgtaaatgct attcgtatct ttctttttcg gatgttataa
     5041 aggt
//
LOCUS       DAPOAV010000176         4959 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.177, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000176 DAPOAV010000000
VERSION     DAPOAV010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4959
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.177"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(251..2320)
                     /gene="glyS"
                     /locus_tag="RN951_004349"
     CDS             complement(251..2320)
                     /gene="glyS"
                     /locus_tag="RN951_004349"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HDX2529238.1"
                     /translation="MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGT
                     VQWFAAPRRLALKVANLAEAQPDREIEKRGPAIAQAFDAEGKPSKAAEGWARGCGITV
                     DQAERLTTDKGEWLLYRAHVKGESTEALLPNMVATSLAKLPIPKLMRWGASDVHFVRP
                     VHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPEILRERGKVIAD
                     YEERKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPAEA
                     LVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFF
                     NTDRKKRLEDNLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVNHATRAGLL
                     SKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVAC
                     ALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAV
                     RLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKA
                     VSHFRTLDAAAALAAANKRVSNILAKSDEVLSDRVNASTLKEPEEIKLAMQVVVLRDK
                     LEPYFTEGRYQDALVELAELREPVDAFFDKVMVMVDDKELRINRLTMLEKLRELFLRV
                     ADISLLQ"
     gene            complement(2330..3241)
                     /gene="glyQ"
                     /locus_tag="RN951_004350"
     CDS             complement(2330..3241)
                     /gene="glyQ"
                     /locus_tag="RN951_004350"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HDX2529239.1"
                     /translation="MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMT
                     CLRALGPEPMAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSL
                     KELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVT
                     GEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDF
                     LFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRI
                     RTLTKAVAEAYYASREALGFPMCNKDK"
     gene            complement(3336..3635)
                     /locus_tag="RN951_004351"
     CDS             complement(3336..3635)
                     /locus_tag="RN951_004351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YsaB family lipoprotein"
                     /protein_id="HDX2529240.1"
                     /translation="MMMNAFFPAMALMVLVGCSIPSPVQKAQRVKVDPLRSLNMEALC
                     KDQAAKRYNTGEQKIDVTAFEQFQGSYEMRGYTFRKEQFVCSFDADGHFLHLSMR"
     gene            3810..4805
                     /gene="wecH"
                     /locus_tag="RN951_004352"
     CDS             3810..4805
                     /gene="wecH"
                     /locus_tag="RN951_004352"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyltransferase WecH"
                     /protein_id="HDX2529241.1"
                     /translation="MQPKIYWIDNLRGIACLMVVMIHTTTWYVTNAHSVSPVTWDIAN
                     VLNSASRVSVPLFFMISGYLFFGERSAQPRHFLRIGLCLIFYSAIALLYIALFTSINM
                     ELALKNLLQKPVFYHLWFFFAIAVIYLVSPLIQVKNVGGKMLLVLMAVIGIIANPNTV
                     PQKIDGFEWLPINLYINGDTFYYILYGMLGRAIGMMDTQHKALSWVSAALFATGVFII
                     SRGTLYELQWRGNFADTWYLYCGPMVFICAIALLTLVKNTLDTRTIRGLGLISRHSLG
                     IYGFHALIIHALRTRGIELKNWPILDIIWIFCATLAASLLLSMLVQRIDRNRLVS"
BASE COUNT         1143 a         1295 c         1247 g         1274 t
ORIGIN      
        1 ctttgattta tagtcaggtg gggcttttct ctgtctgcct ttcggtgaat acctgagaca
       61 aacagtctca agcacccgtg gctattctag cttaataagt ttgtttcttc tccttgatat
      121 aatcctaaaa aaatctcata aaattaatat atgagataat ctttattcag cagaagatta
      181 ttaaaggttg ctgtattatt tagcgataaa aaaagcctgc cagatggcag gctatttaat
      241 aacggcgtta ttattgcaac agcgaaatat ccgcaacgcg caggaacagt tcgcgcagtt
      301 tctccagcat ggtcagacgg ttgatacgca attctttgtc atcaaccatg accatcactt
      361 tatcgaagaa agcatcaacc ggttcacgca gctcagccag ttcgaccagc gcatcctggt
      421 aacgaccttc cgtaaagtac ggctccagct tgtcacgtag caccacaacc tgcatcgcca
      481 gtttaatttc ttccggctct ttcagggtag aggcattcac gcggtcgctc agcacttcgt
      541 cagatttcgc cagaatgtta gatacacgtt tgttcgccgc cgccagtgca gcagctgcat
      601 ccagggtacg gaaatgcgat accgctttca tacgggcatc gaaatcagcc ggacgagtcg
      661 gacgacgcgc cagtaccgcc tggatggtgt caacggtata accttcgtcc tgataccagg
      721 cgcggaagcg accgagcata aagtcgataa catcatcaac tacgttggca ttagtcagct
      781 tatcgccata cagacgcacc gcttcttcgg tcagcgtttg cagatcaagg ttgaggttct
      841 tctcaacgat aattcgcagc acgccaagcg cggcacgacg cagcgcaaac gggtctttgt
      901 cgcctttcgg atgctgaccg ataccgaaga tacccgccag ggtatccatc ttgtcagcaa
      961 tcgccagcgc acaagctact gggttggacg gcaggtcatc accagcaaaa cgcggctgat
     1021 actgctcatt cagcgccacc gcgacatctt ccgcttcgcc atcgtgacgc gcatagtgca
     1081 tccccataac gccctgggtg tcggtgaact cgaagaccat gttggtcatc aggtcgcact
     1141 tagacagcag acccgcacgg gtagcgtggt taacgtcagc gccaatctgt tcagcaatcc
     1201 agccagccag cgcctggatg cggtcagttt tgtcgcgcag cgtccccaac tgttgctgga
     1261 acaacacggt ttgcaggcgc ggcaggttat cttcaagacg ttttttacgg tcggtgttga
     1321 agaagaactc ggcatccgcc agacgcggac gaacgacttt ctcgttaccg gagataatct
     1381 gctgcggatc tttcgattcg atgttggcaa cgaagataaa gttcggcagc agtttgccgt
     1441 cgttcgcata caccgggaag tatttctggt cacctttcat ggtgtaaacc agcgcttcag
     1501 ccggcaccgc gaggaatttc tcttcgaatt ttgcggtcag aacgaccggc cactccacca
     1561 gcgaagccac ttcttccagc aggctttcgc ttaagtcagc gttaccgcca atcttacgcg
     1621 ctgcttcttc ggcatcggct ttaatcttcg ccttacgttc ttcgtaatcg gcgatgactt
     1681 tcccacgctc acgcagaatt tccggatact gatcggcgtt atcgatggtg aattccggct
     1741 cgcccataaa gcggtggccg cgaatcacgc gatcggactg aatgcccaga atggttgccg
     1801 gaatgacttt gtcgcccagc agcagggtca cggtgtgcac cggacgcacg aagtgcacgt
     1861 cgcttgcgcc ccaacgcatc agtttcggga tcggcagttt cgccagagaa gtcgcaacca
     1921 tattcggcag cagtgcttcg gtgctttcgc ccttcacatg ggcgcgatac agcagccatt
     1981 cgcctttatc ggtagtcaga cgctcagcct ggtcaacggt aataccgcaa ccacgcgccc
     2041 aaccttctgc cgctttgctc ggtttgcctt cagcgtcgaa cgcctgggca atcgccgggc
     2101 cgcgcttttc gatttcacga tccggttgcg cttccgccag gttagctact ttcagcgcca
     2161 gacgacgcgg agcagcaaac cattgaacgg tgccgtgtgc gaggccagcg ttatccagct
     2221 ccgcagtaaa gttcgcagca aaggactcag ccaggctgcg cagtgctttt ggtggcagct
     2281 cttcagtgcc gatttccacc agaaaagttt tctcagacat agccgcctct tacttatctt
     2341 tgttgcacat cgggaagccg agggcttcac gggaagcgta gtatgcttct gccactgctt
     2401 tggtcagggt gcgaatgcgc agaatgtagc gctgacgctc ggtgacggag atggctttac
     2461 gcgcatccag caggttgaag ctgtgggcgg ctttcagaat acgctcgtag gctggcagcg
     2521 gcagcggatt ttccagcgcc agcagctgct gcgcttcttt ctcgtactgc tcgaagcagg
     2581 tgaacaggaa gtccacatcc gcgtattcga agttgtaagt ggactgctcc acttcgttct
     2641 gatggaacac gtcgccgtag gtggttttac ccagcgggcc gtcgctccag accaggtcgt
     2701 aaacgctgtc tacgccctga atgtacatgg ccagacgttc cagaccgtag gtgatctcgc
     2761 cggtaaccgg tttacactcc agaccaccaa cctgctggaa gtaagtgaac tgcgtcactt
     2821 ccatgccgtt cagccacact tcccagccca gtccccaggc acccagcgtc gggttttccc
     2881 agttatcttc cacgaaacgg atgtcgtgaa tagtcgggtc catgcccagc tctttcagag
     2941 aaccgaggta cagctcctga atattgtccg gcgatggctt aatgaccacc tggaactgat
     3001 agtagtgctg taaacggttg gggttttcgc cgtagcgacc atcggtcggg cgacgagaag
     3061 gctgaacata agcagccgcc atcggttctg gccccagcgc gcgcagacag gtcattgggt
     3121 gagaggttcc cgcgccgact tccatgtcca atggttgaac aatggtgcag ccctggcgag
     3181 cccagtaatc ctgtaaggtc aggatcaagc cctggaaggt cctggtatca aacttttgca
     3241 tattatttcg tgctggatac gtgtggattt aaaggaaggg atcagtatac ccgctggatg
     3301 gaagatatac agtacgaaac gggaaaaagc agggcttaac gcatggaaag atgcaaaaaa
     3361 tggccatccg cgtcaaaaga acagacaaac tgctctttac ggaaggtata accgcgcatt
     3421 tcatagcttc cctggaactg ttcgaaggcg gtgacgtcga ttttttgctc gccggtgtta
     3481 taacgttttg ccgcctgatc cttgcataac gcttccatat tcaacgaacg cagaggatca
     3541 acctttaccc gttgtgcttt ctgcacgggt gacggtatag aacaacccac tagcaccata
     3601 agcgccattg ccggaaagaa agcgttcatc atcattaaat taccgtctgg tttgcaggtg
     3661 agtcttatta tttatatcgg tatagtggct gatatcttac gaatttcctt aagcctctat
     3721 aagctgtagt gataaaactc agattattcc agtgcgccaa ccaaatgatt tatcggtcag
     3781 acttttttta accagataca gagacacaga tgcagcccaa aatttactgg attgataacc
     3841 tgcgagggat agcgtgttta atggtggtga tgattcacac cactacctgg tatgtgacca
     3901 atgctcatag tgttagcccc gtcacatggg atatcgccaa tgttctgaat tctgcctctc
     3961 gtgtcagcgt gccgctattt ttcatgattt ccggctatct cttttttggc gaacgcagcg
     4021 cccagccgcg ccatttcttg cgtatcggct tatgtctgat tttttatagc gcaatcgcac
     4081 tgctctacat tgcgctgttt acctccatca atatggagtt agcgctgaaa aacctgctgc
     4141 aaaagccagt gttttaccac ttgtggtttt tcttcgcgat tgcggtgatt tatctggttt
     4201 caccgctgat tcaggtgaag aacgtcggcg gaaaaatgtt gctggtgcta atggcggtga
     4261 ttggcattat cgctaaccca aacacagtgc cgcagaaaat tgacggtttt gaatggctgc
     4321 caattaactt atatatcaat ggcgatactt tttactacat tctgtatggc atgttgggcc
     4381 gcgctatagg gatgatggac acacagcata aagcactgtc gtgggtgagc gccgcgctgt
     4441 ttgcgacggg ggtttttatt atctctcgcg ggacattata tgaattgcag tggcgcggaa
     4501 attttgccga tacctggtat ctttactgtg ggccgatggt ttttatctgc gcaatcgcgc
     4561 tattgactct ggttaaaaac acgctggata cgcgtaccat tcgcggactt ggcttaatct
     4621 cccgccattc attgggtata tacggattcc acgccttgat tatccatgcg ctgcgcaccc
     4681 ggggaattga gcttaaaaat tggccaatac tggatattat ttggatcttt tgcgcgacgt
     4741 tggcagcgag tttgttactt tctatgctgg tacaacgaat cgacagaaac agattagtga
     4801 gttaagtaaa agcccggtca cattggactg accgggctta cgtgagttat tcgctgtatt
     4861 cttcctgggt aacctgtgtt tcttttggtg ggtttattcc ggcatcacga atatttttct
     4921 gcaccgctac tgcaccaaac aagcttaaga agaaagcca
//
LOCUS       DAPOAV010000177         4947 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.178, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000177 DAPOAV010000000
VERSION     DAPOAV010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4947
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.178"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..1653)
                     /locus_tag="RN951_004353"
     CDS             complement(<1..1653)
                     /locus_tag="RN951_004353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative relaxase"
                     /protein_id="HDX2529242.1"
                     /translation="MMSIAQVRSAGSAGNYYTDKDNYYVLGSMGERWAGRGAEQLGLQ
                     GSVDKDVFTRLLEGRLPDGADLSRMQDGSNKHRPGYDLTFSAPKSVSMMAMLGGDKRL
                     IDAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQLHTHA
                     VVANVTQHNGEWKTLSSDKVGKTGFIENVYANQIAFGRLYREKLKEQVEALGYETEVV
                     GKHGMWEMPGVPVEAFSGRSQTIRETVGEDASLKSRDVAALDTRKSKQHVDPEIKMTE
                     WMQTLKETGFDIRAYRDAAEQRAYTRTQTPGPASQDGPDVQQAVTQAIAGLSERKVQF
                     TYTDVLARTVGILPPEAGVIERARAGIDEAISREQLIPLDREKGMFTSGIHVLDELSV
                     RALSRDIMKQNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVA
                     ELAMMAREQGREVQIIAADRRSQMNLKQDERLSGELITGRRQLQEGMAFTPGSTVIVD
                     QGEKLSLKETLTLLDGAARHNVQVLITDSGQRTGTGSALMAMK"
     gene            complement(1653..3860)
                     /gene="traD"
                     /locus_tag="RN951_004354"
     CDS             complement(1653..3860)
                     /gene="traD"
                     /locus_tag="RN951_004354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001577029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system coupling
                     protein TraD"
                     /protein_id="HDX2529243.1"
                     /translation="MSFNAKDMTQGGQIASMRIRMFSQIANIMLYCLFIFFWILVGLV
                     LWVKISWQTFVNGCIYWWCTTLEGMRDLIKSQPVYEIQYYGKTFRMNAAQVLHDKYMI
                     WCGEQLWSAFVLATVVALVICLITFFVVSWILGRQGKQQSENEVTGGRQLTDNPKDVA
                     RMLKKDDKDSDIRIGDLPIIRDSEIQNFCLHGTVGAGKSEVIRRLANYARKRGDMVVI
                     YDRSGEFVKSYYDPSIDKILNPLDARCAAWDLWKECLTQPDFDNTANTLIPMGTKEDP
                     FWQGSGRTIFAEAAYLMRNDPNRSYSKLVDTLLSIKIEKLRTFLRNSPAANLVEEKIE
                     KTAISIRAVLTNYVKAIRYLQGIEHNGEPFTIRDWMRGVREDQKNGWLFISSNADTHA
                     SLKPVISMWLSIAIRGLLAMGENRKRRVWFFCDELPTLHKLPDLVEILPEARKFGGCY
                     VFGIQSYAQLEDIYGEKAAATLFDVMNTRAFFRSPSHKIAEFAAGEIGEKEHLKASEQ
                     YSYGADPVRDGVSTGKDMERQTLVSYSDIQSLPDLTCYVTLPGPYPAVKLSLKYQTRP
                     KVAPEFIPRDINPEMENRLSAVLAAREAEGRQIASLFEPDVPEVVSGEDVTQAEQPQQ
                     PQQPQQPQQPQQPQQPQQPVSPAINDKKSDSGVNVPAGGIEQELKMKPEEEMEQQLPP
                     GISESGEVVDMAAYEAWQQENHPDTQQQMQRREEVNINVHRERGEDVEPGDDF"
     gene            complement(4112..4843)
                     /locus_tag="RN951_004355"
     CDS             complement(4112..4843)
                     /locus_tag="RN951_004355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complement resistance protein TraT"
                     /protein_id="HDX2529244.1"
                     /translation="MKTKKLMMVALVSSTLALSGCGAMSTAIKKRNLEVKTQMSETIW
                     LEPASERTVFLQIKNTSDKDMSGLQGKIADAVKAKGYQVVTSPDKAYYWIQANVLKAD
                     KMDLRESQGWLNRGYEGAAVGAALGAGITGYNSSSAGATLGVGLAAGLVGMAADAMVE
                     DVNYTMITDVQIAERTKATVTTDNVAALRQGTSGAKIQTSTETGNQHKYQTRVVSNAN
                     KVNLKFEEAKPVLEDQLAKSIANIL"
BASE COUNT         1077 a         1457 c         1187 g         1226 t
ORIGIN      
        1 cttcatggcc atcagcgcac tgcctgtacc ggttcgctgc ccgctgtcgg ttatcaggac
       61 ctgtacgtta tgacgtgcgg caccgtccag cagggttaac gtctctttca gggagagttt
      121 ttcgccctgg tcgacgataa cggtactgcc cggcgtgaag gccatgccct cctgcagctg
      181 acgacgtccg gttatcagct caccggacag ccgttcatcc tgcttcaggt tcatctgcga
      241 gcgacggtca gcggcgataa tctgcacctc ccgcccctgc tcccgggcca tcattgccag
      301 ttcagccacc cgctcacgct gcccggctgc accgccctgc ccggacacaa tggccagcga
      361 cgggcgatcc tgtgccagaa cactgacggc atcgctgtaa ccggccgtcc gggggacact
      421 tttctccgga tgtacggtca cccggttctg tttcatgatg tcacgactga gtgcccggac
      481 tgacagctca tcgagcacat gaatcccgga cgtgaacatc cccttctcac gatcgagggg
      541 gataagctgc tcacggctga tggcctcatc gataccggcg cgtgcccgct caatcacacc
      601 ggcttccggc ggcagtatgc cgaccgtcct ggccagcacg tccgtgtacg taaactgcac
      661 tttgcgttca cttaatccgg caatcgcctg tgtcaccgcc tgctgcacat ccggcccgtc
      721 ctgtgaagct ggtccgggtg tctgcgtgcg ggtatatgcc cgttgttccg ctgcgtcacg
      781 atacgcccgg atatcgaacc cggtttcctt cagcgtctgc atccactcgg tcattttgat
      841 ttcaggatcg acgtgctgtt tggatttacg cgtatccagc gccgccacat cccgggattt
      901 cagcgaggcg tcctccccga cggtctcccg gatagtctgt gagcgtccgg aaaaggcctc
      961 caccggtacg cccggcattt cccacatacc gtgcttaccc accacttccg tttcatagcc
     1021 cagcgcctca acctgctctt tcagtttttc ccggtagagc ctgccaaagg caatctgatt
     1081 agcgtacaca ttctcaatga accccgtttt ccccactttg tcactgctca gtgtcttcca
     1141 ctcaccgtta tgctgcgtga cattagctac caccgcatgc gtgtgtaact gtggttcctg
     1201 atcgcgactg gtgtcgtggt taaacagtgc catcaccaga ttaccggtca gtaccgtttc
     1261 tgactgtccg tccgtcatca cccgtgtgga ggccagcgcc tccacctgac gaacagcaaa
     1321 gtccacggcc tggttatgtg catcaatcag gcgcttatcg ccacctaaca tggccatcat
     1381 ggagacactt ttgggggcgg agaaggtcag gtcgtagccg ggacgatgct tattactgcc
     1441 atcctgcatg cggcttagat ccgctccgtc cggcagcctt ccctccagaa gacgggtaaa
     1501 aacatcctta tcgacactgc cctgcagtcc cagctgttca gcccccctgc cggcccagcg
     1561 ttctcccatg ctgcccagta catagtaatt atccttgtcg gtataatagt taccggcact
     1621 tccggccgat ctgacctgtg cgatactcat catcagaaat catctcccgg ctcaacatcc
     1681 tccccgcgct cccggtgcac attaatgttc acctcttcac gacgctgcat ctgctgctgg
     1741 gtgtccggat gattttcctg ttgccatgcc tcataagcgg ccatatccac cacttcaccg
     1801 gattcactga tcccgggtgg cagttgctgt tccatctctt cttccggttt cattttcagc
     1861 tcctgctcga tcccccctgc cggaacattc acacctgaat ctgacttctt atcgttgatg
     1921 gcaggagaca ccggctgttg cggctgttgc ggctgttgcg gctgttgcgg ctgttgcggc
     1981 tgttgcggct gttgcggctg ttcagcctga gtcacgtctt ctccggaaac aacctccggg
     2041 acatccggtt cgaagaggct ggctatctga cgaccttctg cttcccttgc ggcaagtacg
     2101 gcactcaggc ggttctccat ttccgggttg atgtcacgcg gaataaactc cggagcgacc
     2161 ttcggtcgtg tctgatattt cagagagagt tttactgccg gatacggtcc gggcagggtg
     2221 acataacagg tcagatccgg cagagactga atgtcggaat aactgaccag cgtctggcgc
     2281 tccatatcct taccggtcga taccccgtca cgtaccggat cagcaccgta ggaatactgc
     2341 tcgctggctt tcaggtgctc tttctcacca atctcaccgg cagcgaactc tgcaatctta
     2401 tggctgggag aacggaaaaa ggcacgggtg ttcatgacgt caaacaacgt ggcagccgct
     2461 ttctcaccgt agatatcttc cagctgggca taggactgga taccaaacac ataacagcca
     2521 ccgaacttac gggcttccgg caggatctcc accaggtcag gcagtttgtg taacgtgggt
     2581 aactcgtcac agaaaaacca cacacgacgt ttacggtttt ctcccattgc cagcagacca
     2641 cgaatggcaa tggacagcca catggagatc accggcttca gggaggcatg ggtgtcggcg
     2701 ttcgatgaga taaacagcca gccgtttttc tgatcttccc ggacaccacg catccagtca
     2761 cggatggtga agggctcacc gttatgctca atcccctgca ggtaacggat ggctttcacg
     2821 tagttggtca gcacagcacg gatggaaatc gccgttttct cgattttctc ttccaccagg
     2881 ttggccgccg gtgaattacg caggaaggta cgcagttttt cgattttgat ggaaagcaga
     2941 gtgtccacca gtttgctgta gctgcggttg gggtcattac gcatcaggta cgccgcttcc
     3001 gcaaaaatgg tacgtcctga accctgccag aacgggtcct cttttgtgcc catcgggatc
     3061 agggtatttg ccgtattatc aaaatccggc tgtgtcagac actccttcca taaatcccat
     3121 gcggcacagc gggcatccag cggattcagg attttatcga tggagggatc atagtaactt
     3181 ttaacaaatt cccctgaacg gtcataaatc accaccatat caccgcgctt acgggcgtag
     3241 ttggccagac gacggataac ttccgactta ccggccccga ccgtgccgtg cagacagaag
     3301 ttctggattt cagaatcccg gataatcggc aggtcgccaa tccggatatc ggagtccttg
     3361 tcgtcttttt tcagcatccg ggcaacgtct ttcggattgt ctgtcagctg acgaccacct
     3421 gtgacttcat tttcgctctg ttgtttaccc tgacgcccca gaatccagga gacaacaaag
     3481 aaggtaatca ggcaaataac cagtgccaca actgtggcca gaacgaatgc ggaccatagc
     3541 tgctctccgc accaaatcat atatttatca tgcagtacct gagcagcgtt catccggaag
     3601 gttttgccgt aatactggat ctcatatacc ggctgggact tgattaaatc ccgcatgcct
     3661 tccagcgtgg tacaccacca gtaaatacag ccgttcacaa acgtctgcca gcttattttt
     3721 acccataaaa ccagaccaac gagtatccag aaaaaaataa acaggcagta aagcatgata
     3781 ttggcgatct ggctgaacat gcggatacgc atggacgcaa tctgaccgcc ctgggtcata
     3841 tcctttgcgt taaaactcat gatgacattc cgaagaaaaa agtcagtcgg actgattatt
     3901 aatgatgaaa agattaataa ccgttaaatt ccggcttcgc cggcaacact tcacggtcgc
     3961 acaaagaatt tgcacaaccg ctcagtgttt tcatatttat ttcggaaacg ccggggagaa
     4021 ataaaattta ttttatttct ccccggggtt ggacaacgag caaagcgagg cgtcagtcag
     4081 gaggccggtc agaccagcct ccggaagata atcagagaat atttgcgatt gatttggcca
     4141 gctggtcttc gagaacaggc ttcgcctctt caaatttcag gttaaccttg ttcgcatttg
     4201 agaccacacg ggtctggtat ttatgctggt tacctgtttc agtactggtc tgaattttcg
     4261 cacctgatgt gccctgacgc agggcggcaa cattatccgt tgtcaccgtt gccttagtac
     4321 gctctgcaat ctgcacatcc gtgatcatgg tatagttcac atcttccacc atcgcatctg
     4381 cagccatacc caccagaccg gcagcaaggc ccacaccgag tgtggcaccg gcagaactgg
     4441 aattatatcc ggtgataccg gcacctaacg ctgcaccaac tgctgcgcct tcataaccac
     4501 ggttcagcca tccctgagac tcccgcagat ccatcttatc ggccttcagc acattcgcct
     4561 gaatccagta gtaggcttta tccggagaag tcaccacctg ataccctttt gctttcacag
     4621 catcagcaat tttgccctgc agcccactca tgtctttatc agacgtgttt ttgatctgca
     4681 gaaataccgt gcgttcgctg gcgggttcaa gccagatggt ctcactcatc tgagtcttca
     4741 cctcaaggtt acgcttcttg attgctgtgc tcatcgcacc acaccctgaa agggccagag
     4801 tggaactgac cagtgcaacc atcatcaatt tttttgtttt catccaaaat atccttttaa
     4861 ctaacagact cttttttgaa cagtcctatt actgagacta ttgctgagag attataacga
     4921 tttatatcta tggtatacac caagaaa
//
LOCUS       DAPOAV010000178         4891 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.179, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000178 DAPOAV010000000
VERSION     DAPOAV010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4891
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.179"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..851)
                     /gene="repA"
                     /locus_tag="RN951_004356"
     CDS             complement(<1..851)
                     /gene="repA"
                     /locus_tag="RN951_004356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="incFII family plasmid replication initiator
                     RepA"
                     /protein_id="HDX2529245.1"
                     /translation="MTDLQQTYYRQVKNPNPVFTPREGAGTLKFCEKLMEKAVGFTSR
                     FDFAIHVAHARSKGLRRRMPPVLRRRAIDALLQGLCFHYDPLANRVQCSITTLAIECG
                     LATESGAGKLSITRATRALTFLSELGLITYQTEYDPLIGCYIPTDITFTSALFAALDV
                     SEEAVAAARRSRVEWENRQRKKQGLDTLGMDELIAKAWRFVRERFRSYQTELKSRGIK
                     RARARRDANRERQDIVTLVKRQLTREISEGRFSASREAVKREVERRVKERMILSRNRN
                     YSRLATAS"
     gene            complement(844..918)
                     /gene="tap"
                     /locus_tag="RN951_004357"
     CDS             complement(844..918)
                     /gene="tap"
                     /locus_tag="RN951_004357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001370046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA leader peptide Tap"
                     /protein_id="HDX2529246.1"
                     /translation="MPGKVQDFFLCSLLLRIVSAGWCD"
     gene            complement(1153..1410)
                     /gene="repA"
                     /locus_tag="RN951_004358"
     CDS             complement(1153..1410)
                     /gene="repA"
                     /locus_tag="RN951_004358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication regulatory protein RepA"
                     /protein_id="HDX2529247.1"
                     /translation="MSQTENAVTSSSGAKRAYRKGKPLSEAERQRAASARKRSVCKEI
                     KVFVRPELKNCLTSLCAEEGVTQAELIERLIEKEACHRNMM"
     gene            1815..2837
                     /locus_tag="RN951_004359"
     CDS             1815..2837
                     /locus_tag="RN951_004359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HDX2529248.1"
                     /translation="MTITTIGIDLAKNVFAVHGVDQNGKTVLVKSRVTRAALPGLIAS
                     LPPCVIGMEACSGAYYWARLFLQYGHEPRLMAAKFVSPYRMAGKSGKNDAADAQAICE
                     AVRRPHMRFVPVKDESQQAMQCLHRNRQGFIEEKTATYNRLRGLISEFGVIAPQSTDA
                     LRHMVSAQKSSLPLQVQQCVDDLLEHVDRIEANITEYDRILSRIAKTDHRSQRLMKLK
                     GVGPTTACALVACIGNAHDFKNGRQLAAWLGLTPSQYSSGGKSKLGRITKAGDSYLRT
                     LLVQGARSVLIGAEKRTDLFSRWVCSLVERRGYWRAVVAIAAKNARLCWASLHYGDDF
                     RLYSAS"
     gene            3309..3662
                     /locus_tag="RN951_004360"
     CDS             3309..3662
                     /locus_tag="RN951_004360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529249.1"
                     /translation="MSETVQIESFNAEFLTKQKLHDLIFYRKSFDITNVNDISETVKI
                     VEYVIEHQQKKLTCRVYTEYRSTAVAGSLWSPTALLGAVSAAAIGVHNLATWNPDYEI
                     GKNYVKRTISVRYKK"
     gene            complement(4075..4653)
                     /locus_tag="RN951_004361"
     CDS             complement(4075..4653)
                     /locus_tag="RN951_004361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="HDX2529250.1"
                     /translation="MSKLAASPIAALLIRIILRSVNQHSPLLMQLHAAGIRTGDAERI
                     LSSGECWQRQKTLLTGREVSFMKGLFRIVDMKRWYLCPQVRVADIVQLNGNIRPRSRQ
                     WWQLFRMVSQWHVDVVIVERRSFSIVAAVELDDASHLRPERRRRDILLEEVLRQAGIP
                     LLRSHDARKLLQMTGEWLNTTGADQQSPEHRS"
     gene            4686..>4891
                     /locus_tag="RN951_004362"
     CDS             4686..>4891
                     /locus_tag="RN951_004362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="HDX2529251.1"
                     /translation="MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFT
                     YTASQPGTHQKIIDMAMNGVGCRAT"
BASE COUNT         1248 a         1230 c         1175 g         1238 t
ORIGIN      
        1 gaagcggtgg ccagccggct gtaattgcgg ttacgtgaca gaatcatgcg ctccttcaca
       61 cgacgctcca cttcacgttt taccgcctca cgactggcag agaagcgccc ttccgagatt
      121 tcacgcgtca gctgccgttt caccagggtg acgatatcct gacgttccct gttcgcatca
      181 cgacgcgcac gggcacgctt tattccccgg gacttaagct ctgtctggta actgcggaaa
      241 cgctcacgga caaaacgcca ggctttcgct atcagttcat ccatacccag ggtatccagc
      301 ccctgctttt tgcgctgtct gttttcccat tccacacggc tgcggcgcgc ggcggccact
      361 gcctcctctg atacatcgag ggcagcaaac agtgcagatg tgaacgtgat atcggtcgga
      421 atgtagcacc cgataagcgg gtcatattcc gtctggtagg taatcagtcc cagctctgac
      481 aggaacgtca gagcccgggt ggcacgggtg atggagagtt ttcctgcacc ggactctgtc
      541 gccagcccgc actcaatggc cagcgtggtg atggagcact ggacacggtt ggccagcggg
      601 tcatagtgga aacacagccc ctgcagcagc gcatcaatag cccgtcgacg cagcaccggt
      661 ggcatgcgcc gacgcagtcc cttcgaacgg gcatgcgcca catgaatagc gaaatcaaaa
      721 cgggaggtga agcccaccgc cttttccatc agtttttcgc agaacttcag cgttcctgca
      781 ccttcacggg gtgtaaacac cggattcggg ttctttacct ggcggtaata cgtttgttga
      841 agatcagtca caccatcctg cgcttacaat gcgcagaagg agtgagcaca gaaagaagtc
      901 ttgaactttt ccgggcatat aactatactc cccgcatagc tgaattgttg gctatacggt
      961 ttaagtgggc cccggtaatc ttctcttagt cgccaaacct ggtgaaggtt atcggggttt
     1021 ttgcttttct ggctcctgta aatccacatc agaaccagtt ccctgccacc ttacggcgtg
     1081 gccagccaca aaattcctta aacgatcagt aatctagcac tgacagaaaa aactagcaag
     1141 aatgtgaccc catcacatca tgttccggtg acaggcctct ttctcgataa gcctttctat
     1201 caactctgcc tgagttaccc cttcctctgc acacagactg gtaaggcagt ttttcagttc
     1261 tggtctgacg aaaaccttga tctctttaca tacagatcgt ttgcgcgcag aagctgctct
     1321 ctgtcgttct gcttcactca aaggtttacc ctttctgtat gctcgttttg caccagatga
     1381 ggaagtcact gcattttctg tctgcgacat ctcgcctcct caatactcaa acagggatcg
     1441 tttcgcagag aatactacag ttttttgaaa tcagcgactt gagaattgtg acgaagatct
     1501 gtgttggcgc acaaatcaac ggggattact gtcgtttaag ggctgcgttt gggaaacgta
     1561 caatattgta cggttgcgtt atcgcgctcg gacgctatac ggtgtttggc agacctttag
     1621 ggacatgaga taacctaaat gcgataagag aaaagcaata acttaaaggc gatagctgat
     1681 cacgatgaat caatcagtta cttatcagta tcggttaaaa aatgccccta acgaatggaa
     1741 gggacttccc ctggatatgc acctgattaa ctcttgtgca atcatggggt aaacatagcc
     1801 tggagagatt cgttatgacc atcactacta tcggtatcga tcttgctaaa aatgtgttcg
     1861 ctgttcatgg ggttgaccaa aatggcaaaa ccgttctggt gaaatccaga gtaacccgcg
     1921 cagctcttcc cgggctgatt gcaagtttac cgccctgtgt tatcgggatg gaggcgtgct
     1981 ccggggctta ttactgggca agattgtttc tgcaatatgg tcatgagccg cgtctgatgg
     2041 ccgctaaatt tgtatctcca taccgcatgg ccggtaaatc agggaaaaat gatgcagctg
     2101 atgctcaggc tatctgcgaa gcggttcgtc gcccacatat gcggtttgtt ccagttaagg
     2161 acgagagcca gcaggcgatg cagtgtctgc atcgtaaccg acagggtttt atcgaagaga
     2221 aaacagcaac atataatcgt cttcgagggt tgatatcaga attcggcgtc attgccccac
     2281 aaagtacaga tgctttgcgg cacatggttt ctgcgcagaa gagctcttta cctcttcagg
     2341 ttcagcaatg tgtagatgat ttactggaac acgttgatcg cattgaagct aacatcactg
     2401 aatatgaccg aattttgtcc cgcatagcca aaacagatca ccgcagtcag cggctgatga
     2461 agctaaaagg agttggtccc acaactgcct gtgctctggt tgcctgtatc ggtaatgcac
     2521 atgattttaa aaatggacgg caactggcgg cctggctggg gttgactcca tcgcaataca
     2581 gtagcggcgg aaagtcgaag ttaggcagga taacaaaagc cggtgattcg tatctgcgaa
     2641 cgcttctggt acagggggct cgttcagtac tgattggcgc tgagaaaagg actgacttat
     2701 tcagtcgttg ggtctgttca ctggtcgaac gcagaggata ctggcgcgct gttgtggcca
     2761 tcgccgccaa aaatgcaagg ctgtgctggg catcattgca ttacggtgat gatttcaggc
     2821 tgtattcagc aagctaaagc aggaagaaac cgtatgacca tctgatctgc aactcgttga
     2881 tgataaaggg ttagaccccg tgaggtatat ctgattattg tacaggatat acgtatccgc
     2941 ttaacgaaca agagcctcac gcgcgtcttt catcagggtc cgaatcgata gcgattcatt
     3001 atggccgttt atagtaccgc agtctctccc ctttattttt aactgtagtg cagacacaaa
     3061 ccataaatac cgacgttgac tgttcgggga agcccttata gtacaaaaat gtccgatctc
     3121 caaaccgccc ccacatacgg cagtcggttt acgcttacag ttaagacgat caatttctta
     3181 ttattgatcg tttatacaag tcaatatatt cttttctgac atacactgcc cctgaaaaag
     3241 tgcaacgttt gaccgtaagg cgcgtgccta gggaaattca cagactccaa gaaagagagg
     3301 aacaacggat gtcagaaacg gtacagattg agtcgttcaa cgcagaattt ttgaccaaac
     3361 agaaactaca cgacctgatt ttttaccgca aaagttttga tatcacgaat gttaacgaca
     3421 tcagtgaaac cgtcaaaata gtggagtatg tgattgaaca tcagcagaag aaattaacct
     3481 gccgcgtata caccgaatac agaagcactg cggtggcagg ctccctatgg tcaccaacag
     3541 cacttctggg agctgtgagt gctgccgcaa tcggtgtcca taatctggcg acatggaacc
     3601 cggactatga aattggtaag aattacgtca aaagaaccat atctgtaagg tataaaaagt
     3661 aacgggttta tatctgtccg gttcagccaa aatcctctcc cataattcct atgcgagctg
     3721 aacgggggca gtctggagat cgaaaaattt tgaacgttaa gcgcattatt taaccaatag
     3781 atatgcataa cagattgatt ttgcgtcaac gtctatccct tttaagttat cgccattgca
     3841 gtattgcatt taggttatcc gattgaggtc aaatcctctg aaaacgccgt atagcacggg
     3901 agtacacccg agcgcgataa cgcaaccgta caatattgta cgtttcccaa acgcagccct
     3961 ttaatgtgat ttaaactgtg aaatagtatg gttttcagtt atggaaacgc cgggagcggg
     4021 gaaaacttgc tttttcccgt ttccggggtt ggacaactga gcaacgcgaa ggcgtcagct
     4081 acgatgttcc ggggactgct gatcagcccc tgttgtattc agccattctc cggtcatctg
     4141 cagcagtttt ctggcatcgt ggcttctgag caacggaata ccagcctgcc tcagaacctc
     4201 ttccagaaga atatcccggc gtctgcgttc cggtcgtaaa tgactggcat catccagctc
     4261 tactgctgca acaatactga acgaacgccg ctcaacgata accacatcaa catgccactg
     4321 agacaccatc ctgaataact gccaccactg gcgtgatcgt ggccggatat tcccgttcag
     4381 ctggacgata tccgcgaccc gtacctgcgg acacagatac caccgcttca tatccacaat
     4441 tctgaacagt cctttcataa aactgacttc ccttcctgtc agcagcgtct tctgacgttg
     4501 ccagcattca ccgctggaca gtattcgctc tgcatcaccg gtccgtatac ctgccgcatg
     4561 caattgcatc agcaaaggag aatgctgatt tacacttctg aggataatcc ggataagtaa
     4621 cgctgcaata ggtgatgctg ccaacttact gatttagtgt atgatggtgt ttttgaggtg
     4681 ctccagtggc ttctgtttct atcagctgtc cctcctgttc agctactgac ggggtggtgc
     4741 gtaacggcaa aagcaccgcc ggacatcagc gctatctctg ctctcactgc cgtaaaacat
     4801 ggcaactgca gttcacttac accgcttctc aacccggtac gcaccagaaa atcattgata
     4861 tggccatgaa tggcgttgga tgccgggcaa c
//
LOCUS       DAPOAV010000179         4888 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.180, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000179 DAPOAV010000000
VERSION     DAPOAV010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4888
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.180"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            17..544
                     /locus_tag="RN951_004363"
     CDS             17..544
                     /locus_tag="RN951_004363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDX2529252.1"
                     /translation="MAVRGINKVILVGRLGKDPEVRYIPNGGAVANLQVATSETWRDK
                     QTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGAQVYIEGQLRTRSWEDNGITRYVTEIL
                     VKTTGTMQMLGSAPQQNAQVQPQPQQNGQSQSADATKKGSAKTKGRGRKAAQPEPQPQ
                     PPEGEDYGFSDDIPF"
     gene            602..835
                     /locus_tag="RN951_004364"
     CDS             602..835
                     /locus_tag="RN951_004364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HDX2529253.1"
                     /translation="MSEYFRILQGLPDGPFTRKQAEAVAAQYRNVFIEDDHGEQFRLV
                     VRNNGTMVWRTWNFEDGAGYWMNHVIRDFGILK"
     gene            896..2919
                     /locus_tag="RN951_004365"
                     /pseudo
     CDS             896..2919
                     /locus_tag="RN951_004365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052657.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
     gene            2988..3422
                     /gene="psiB"
                     /locus_tag="RN951_004366"
     CDS             2988..3422
                     /gene="psiB"
                     /locus_tag="RN951_004366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000845953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugation system SOS inhibitor PsiB"
                     /protein_id="HDX2529254.1"
                     /translation="MKTELTLNVLQTMSAQEYEDIRAAGSDERRELTHAVMRELDAPD
                     NWTMNGEYGSEFGGFFPVQVRFTPAHERFHLALCSPGDVSQVWVLVLVNAGGEPFAVV
                     QVQRRFAPEAVSHSLALAASLDAQGYSVSDIIHILMAEGGQA"
     gene            3419..4138
                     /locus_tag="RN951_004367"
     CDS             3419..4138
                     /locus_tag="RN951_004367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001763821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid SOS inhibition protein A"
                     /protein_id="HDX2529255.1"
                     /translation="MSARSQALVPLSAEQQAAWRAVAETEKRRHQGNTLAEYPYAGAF
                     FRCLNGSRRISLSDLRFFMPSLTAEELRGNRSQWLYAVDVLIETQGEVCLLPLPGDAA
                     ERLFPSVRFRVRERSRHKSALVMQKYSRQQAREAEQKARAYQALVAQAEIELAFHSPE
                     TVGSWHARWSDRVAEHDLETLFWQWGERFPSLAGMERWQWQDMPFWQVIAEASLAARE
                     AGHAVREMERWMVPNKLREAA"
     gene            complement(4159..4338)
                     /locus_tag="RN951_004368"
     CDS             complement(4159..4338)
                     /locus_tag="RN951_004368"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="protein sok"
                     /protein_id="HDX2529256.1"
                     /translation="MKINLLRGYLLSATQHGNKPPSRHEAESLKRRAHHSPYTCTLTT
                     LTFPENNPLIQAVYG"
     gene            4418..4576
                     /locus_tag="RN951_004369"
     CDS             4418..4576
                     /locus_tag="RN951_004369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HDX2529257.1"
                     /translation="MKLPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGHREVAA
                     FMAYESGK"
BASE COUNT         1099 a         1289 c         1519 g          981 t
ORIGIN      
        1 cagaaggaga cacatcatgg cagttcgtgg cattaacaag gtcattcttg tcggtcgtct
       61 gggaaaagat ccggaagtcc gttacatccc caacgggggc gcagtggcaa acctgcaggt
      121 ggccacgtca gaaacctggc gcgacaaaca gacgggggaa atgaaggagc agacggaatg
      181 gcaccgcgtg gtgctgttcg gcaagctcgc ggaagtggca ggtgaatatc tgcgtaaggg
      241 ggcgcaggtc tacattgaag gccagcttcg cacccgtagc tgggaagata acggtattac
      301 ccgttacgtc accgaaatcc ttgttaaaac cacgggcacc atgcagatgc tggggagtgc
      361 accacagcag aacgctcagg tgcaaccgca gcctcagcag aatggtcagt cacagagtgc
      421 tgacgcgacg aaaaaaggga gcgcgaaaac gaaaggccgt ggacgtaagg ctgcgcagcc
      481 ggagcctcag ccgcaaccac cggaggggga ggattacggg ttttcagacg atatcccgtt
      541 ctgactggcc tgactgtgat aaccgccccg tcctgcgcgg ggcatcaccg gagatatgag
      601 gatgagcgaa tatttcagaa tacttcaggg actgcctgac ggtcctttta cccgcaaaca
      661 ggccgaagcc gttgccgcac agtaccggaa cgtctttatc gaggatgacc acggcgaaca
      721 gtttcgcctg gttgtccgta ataacggaac aatggtctgg cgtacctgga attttgagga
      781 cggtgccggg tactggatga accatgtcat ccgtgatttc gggatcctta agtaagagag
      841 gtgccggacg gggatcacgt ccggcagaca ttaactacac aataagggga tagtcatgtc
      901 agtaacaaag tctgaaccaa aatctacccg taaagcaagc cgtaaacctg caaaaacgca
      961 ggaaactgtc ctgtctgccc tgctggcgca gacggaggaa gtgagcgtgc cgctggcctc
     1021 gctgattaag tcaccactga atgtgcgcac ggtgccgtat tctgcggagt ccgtcagcga
     1081 actggctgat tccattaagg gggtcggcct gctgcagaat ctggttgttc atgccctgcc
     1141 aggtgaccgc cacggtgtcg ccgcaggtgg tcgccgactg gcagcactca acatgctggc
     1201 agagcgtggc atcattccgg ctgactggcc tgtccgcgtg aaaattattt cgcaggaact
     1261 ggcgacggcc gcatcgatga ccgagaacgg tcatcgtcgg gatatgcacc cagccgaaca
     1321 gattgccgga ttctgtgcaa tggcgcagga aggcaaaaca cctgcacaaa tcggtgattt
     1381 gctgggctat tcaccccgcc acgttcagcg aatgctgaaa ctggctgacc ttgcgcctgt
     1441 catcctcgat gcgctggcag aagacctcat caccaccgag cactgtcagg cgctggcgct
     1501 ggagaacgac accgcgcgtc aggtgcaggt gtttgaagcc gcctgtcagt cgggatgggg
     1561 cggtaaaccg gaagtacaga ccattcgtcg tctggtgacc gaaagtgaag tggcggtggc
     1621 agggaacagt aaattccgct tcgtgggggc tgatgccttc tcgccagatg aactgcgcac
     1681 tgacctgttc agcgacgacg agggtggcta tgtggactgc gtggcgctcg atgccgccct
     1741 gctggaaaaa ctccaggctg ttgctgaaca ccttcgggaa gccgaaggct ggggatggtg
     1801 cgccggacgc atggagcctg tcggtgagtg ccgtgaggat gccggaacat accgctgtct
     1861 gccggagccg gaagcggtgc tgacggaggc ggaagaagaa cgtctgaacg aactgatgac
     1921 gcgttacgac gcgctggaaa accagtgtga ggaatctgac ctgctggaag cagaaatgaa
     1981 gctgatgcgc tgcatggcga aggtcagggc gtggacgccg gagatgcgtg ccggaagcgg
     2041 tgtggtggtg tcctggcgtt atggcaacgt gtgtgtccag cgtggtgtgc agttgcgcag
     2101 cgaggatgat gcggctgacg acgctgaccg cacggaacag gtgcaggaga aagcgcccgt
     2161 ggaggaaatc agtctgccac tgctgacgaa aatgtcttcc gaacgcacgc tggcagtcca
     2221 ggcagcactg atgcagcaac cggacaaatc tctggcactg ctggcatgga cgctctgccc
     2281 tgatgaatcc cctaatgatt tttaccaaaa tcattagggg attcatcagc gctctgcctg
     2341 aatgtgtttg gcagcggagc gtacagtaaa ccagcacaaa tcagcctgga atgtaaacat
     2401 tattcgctga ccagcgatgc gccatcgggg aaggacggtg ccgcattcct ggcgctgatg
     2461 gcagaaaaag cccgtcttgc agccctgtta ccggagggat ggtcacggga tatgacgaca
     2521 ttcctgtcac tcagccagga ggtactgtta tccctgctca gtttctgcac cgcgtgcagc
     2581 atccacggcg ttcagacccg cgagcatggt cacacgtcac gcagtccgct ggactcgctg
     2641 gagagcgcta tcggattcca catgcgcgac tggtggcagc cgacgaaagc aaacttcttc
     2701 ggacacctgc aaaagccgca gattatcgat gccctgaatg atgccggact gtccggtgct
     2761 gcgcgggacg cggagaaaat gaagaaaggc gatgccgctg aacatgcaga gttccacatg
     2821 aaagacaacc gctgggtgcc tggctggatg tgtacaccac gtccacaggc agagacggaa
     2881 accacggagt accgtgacga ccaggcagaa gccgcctgac cgccagtcat aaaccattta
     2941 tcacgccgcc ctgccggaga cggggcggca gcaagggaga taccgtgatg aaaactgaac
     3001 tgaccctgaa tgtattacag accatgagcg cacaggaata tgaagatatc cgggctgccg
     3061 gaagtgatga acgtcgtgaa ctcacacatg ccgtgatgcg ggagctggat gcgccggata
     3121 actggacgat gaacggcgag tatggcagcg agttcggcgg ctttttcccc gtccaggtcc
     3181 gtttcacgcc tgcccacgaa cgttttcacc tggcgttatg ttcaccgggc gatgtctctc
     3241 aggtctgggt gctggttctg gtgaatgccg gtggtgagcc gtttgcggtg gttcaggtac
     3301 agcggcggtt tgcaccggaa gccgtcagcc attcactggc actggcggcg tcactggacg
     3361 cgcaggggta cagcgtcagt gacatcatcc atatcctgat ggcggaagga ggtcaggcat
     3421 gagcgcacgt tcacaggcac tggttcccct cagcgcagag caacaggccg catggcgggc
     3481 ggtggcggag acagaaaaac gccgccacca gggaaacacg ctggcggaat atccgtatgc
     3541 gggggcgttt ttccgctgtc tgaacggaag ccgcaggata tcgctgtctg acctgcgatt
     3601 tttcatgccg tccctgaccg cagaagaact gcgcggcaac cgttctcagt ggctgtatgc
     3661 cgtcgatgtg ctgattgaaa ctcagggcga ggtctgcctt cttccccttc ccggcgatgc
     3721 agcagagcgg ctgttcccgt cggtgcggtt ccgtgtcagg gagcgcagtc gccacaaatc
     3781 cgcactggtc atgcaaaagt acagccgcca gcaggcgagg gaggcagagc agaaagcccg
     3841 tgcgtaccag gcgctggtcg ctcaggctga aatcgaactg gcattccatt cgccggaaac
     3901 agtcggaagc tggcatgcac gctggagtga ccgggtggca gagcatgacc tggaaaccct
     3961 gttctggcag tggggtgagc gttttccgtc actggccgga atggaacgct ggcagtggca
     4021 ggatatgccg ttctggcagg ttattgcgga agccagtctt gcagcaagag aggccggtca
     4081 cgctgtccgt gagatggagc ggtggatggt gccgaacaaa ctccgggagg cggcgtgatg
     4141 cggcaacaat cacacagatt acccgtaaac agcctgaatg agcgggttat tttcaggaaa
     4201 agtgagtgtg gtcagcgtgc aggtatatgg gctatgatgt gcccggcgct tgaggctttc
     4261 tgcctcatga cgtgaaggtg gtttgttacc gtgttgtgtg gcagaaagaa gatagccccg
     4321 tagtaagtta attttcatta accaccacga ggcatcccta tgtctagtcc acatcaggat
     4381 agcctcttac cgcgctttgc gcaaggagaa gaaggccatg aaactaccac gaagttccct
     4441 tgtctggtgt gtgttgatcg tgtgtctcac actgttgata ttcacttatc tgacacgaaa
     4501 atcgctgtgc gagattcgtt acagagacgg acacagggag gtggcggctt tcatggctta
     4561 cgaatccggt aagtagcaac ctggaggcgg gcgcaggccc gccttttcag ggctgatgct
     4621 ggtctgactg cactgaagcg cctttataaa ggggctgctg gttcgccggt ggcccctttc
     4681 tccttgctgg cattgtacgg gcatgaacaa ccagactgcc aggaaggccg tttccctccg
     4741 ggaacgggga tgaacgtgcg cctgcggcgc ccgttctttt cccccgcctt ctctgtttat
     4801 gacttaccag aaatcacatc accttccctt tgattattct ctttttcctc ctgctctgac
     4861 tctgattact gctctgactc tgattact
//
LOCUS       DAPOAV010000180         4858 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.181, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000180 DAPOAV010000000
VERSION     DAPOAV010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4858
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.181"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..348
                     /locus_tag="RN951_004370"
     CDS             <1..348
                     /locus_tag="RN951_004370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDX2529258.1"
                     /translation="NIFGASFTNTRIKNLLCEDIMPGRWTTQLVNKHLGYRYTGVFKT
                     LASIDDKPSRFEILIPLIQTLVRDNVKLNNDVYKELKKFMHDYDKTSPEMRKYLKSIN
                     ECMFLMKNIAHHN"
     gene            650..1183
                     /locus_tag="RN951_004371"
     CDS             650..1183
                     /locus_tag="RN951_004371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX2529259.1"
                     /translation="MKKYIIPFVATTLMFSATTFAKDVDQGTLTIRGEVVDTTCYFVN
                     GDSTTDIVVEDVVTSAMNQLITNEIYTLKTGSTSHDLEIQCDGNTAPSIEVLASEFDA
                     NNFTLNKGTAENIGFAIFLDDGTLTRMRPGLKTPLKDNGTGQYFLNLSAQYARTSGNP
                     VTKGSVESTVTIKISAD"
     gene            1233..1916
                     /locus_tag="RN951_004372"
     CDS             1233..1916
                     /locus_tag="RN951_004372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HDX2529260.1"
                     /translation="MRIIIALLMSFFILPVHAGMVIYGTRIIYPKKNREVLVQLMNQS
                     KNASLIQAWIDDGNTTIAPEKIQVLFILTPPVSRVAGGSGQQLKIRKMPNNLPHNKES
                     LFYLNVLDIPPNNPQNAGKNKIKLAFQNRIKLLWRPSGIAPVDKKSLSQLNIKKKNNA
                     ISINNETANWITVTTIKAQNVKVNNESILLPPFSNNDITLKNNHASEYELTVVDDYGN
                     NIHSKIAAR"
     gene            1929..4379
                     /locus_tag="RN951_004373"
     CDS             1929..4379
                     /locus_tag="RN951_004373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDX2529261.1"
                     /translation="MLRTTRWVAAIIFLYSFPGYAEETFDTHFMIGGMRGEKVSEYRF
                     DNKQPLPGNYELDFYVNHQWRGKKDITIPESPAKPCLPKVLLTTLGVKTDNLNTEDNC
                     ILLDEAVHGGQYQWDISEHRLNLTIPQAYINELERGYVPPESWDRGIDAFYTSYNLSQ
                     YRSYDSNNNSNTASYGRFNSGLNLFSWQLHSDASYSKPDDMKGKWQSNTLYLERGWSQ
                     ILSTVQIGENYTSSLIFDSLRFSGIRLFRDMQMLPDSMQSFTPLVQGVAQSNALITVS
                     QNGYIIYQKEVPPGPFTIADLQLSGSGADLDVSIKEADGSVRSFLVPYSSVPNMLQPG
                     VSNFDFIAGRSKIYGVKNQEDFLEANYIYGLNNLLTLYGGTILSDNYNAITLGNGWNT
                     PLGAISFDATRSSSKLNNDITHEGTSYQVAYNKYLVQTATRFSVAAWRYASQDYRTFS
                     DHLYENDKHNHQSEYDDFYDIGRKNSLSANIMQPLSNNLGNVSLSALWRNYWGRSGNA
                     KDYQFSYSNSWQRISYTFSASQSYDENDKEEERFNLFISIPFYWGDDITKTRHQINLS
                     NSTSFSKDGYSSNNTGVTGIAGEHDQLNYGIYVNQQQQNNDTSLGTNLSWRTPIAIID
                     GSYSHSKNTWQSGGSISSGLVVWPGGINITNQLSDTFAILDAPGLEGAHINGQKYNRT
                     NSKGQVVYDLMIPHRENHLVLDIANSESETELQGNRQIIAPYRGAVSYVQFTTDQRKP
                     WYIQALRPDGSPLTFGYDVLDLQENNIGVVGQGSRLFIRVDEIPTGIKVALNDEQNLF
                     CTITFQHVIDENKTYICQ"
     gene            4392..>4858
                     /locus_tag="RN951_004374"
     CDS             4392..>4858
                     /locus_tag="RN951_004374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000871680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial family protein"
                     /protein_id="HDX2529262.1"
                     /translation="MKWLLLITLSLYSFIVQSAPCAVTNVGEQRGTYILKPLSMKGNL
                     TAEKNENTGNIIECADLQETTNAIKVHFLTQNALRFKVGSRHYIINFPFESDGKKIEL
                     PGKASYNLEEMLSAINFTIPYSIASVQDSSNTADIFPGTPFPLLFEIEVSSCTG"
BASE COUNT         1611 a          958 c          929 g         1360 t
ORIGIN      
        1 aacatatttg gagcatcatt cactaatacc agaataaaaa atttgctctg tgaagatatt
       61 atgcctggtc gatggaccac tcaacttgtc aataagcacc tgggttacag atacacagga
      121 gtattcaaaa ccctggcaag tattgatgac aaaccgtccc gtttcgaaat tttgatacca
      181 ttgatacaaa ctttagttcg cgacaatgta aagctaaata atgatgtgta taaagaactg
      241 aaaaagttta tgcacgatta cgacaaaaca tccccagaaa tgagaaaata ccttaaaagc
      301 atcaacgagt gtatgttcct tatgaaaaac atagctcatc acaattaaaa caccccaaaa
      361 aagaagtaat ttcagaatga aattatctgt gatgattatt aattcactgc agagaaataa
      421 aaaataatct gaagcatgct ctgaaacatc ctactctgtc attctaatga tggaaacttg
      481 ctcttattat aaagaaggaa acaattaaga atattaaatt ttcgaacttt catcaacttc
      541 acatcaagaa attaaaaaac ttaaacatta atctaaataa taacaacctg atcacataat
      601 cgggtttgac aacgagtgac cttccatacc agttaattaa ggatgattta tgaaaaagta
      661 tattattccc ttcgttgcga caacgttgat gtttagcgca acaaccttcg ccaaggatgt
      721 cgatcaagga acactaacca ttagaggaga agttgttgat acaacgtgtt actttgttaa
      781 tggtgattcg acaacagata tcgttgtcga agatgttgta accagtgcaa tgaatcaact
      841 tatcactaat gaaatctata ctttaaaaac cggttcaacc tctcatgatt tagaaattca
      901 gtgtgacggc aatacagccc caagtatcga agtactagca tctgagtttg atgctaataa
      961 ctttacgctg aataaaggaa ctgctgagaa cattggcttt gccattttcc tcgatgatgg
     1021 gactttgacc agaatgagac cggggttaaa aacaccgctg aaagataatg gcactggtca
     1081 atattttctt aatttaagtg cacaatatgc ccgcacaagt ggcaatcctg ttacaaaagg
     1141 ctctgtagag tcaaccgtaa cgattaaaat cagtgcagat taacgttttt tgccggtagc
     1201 tctgctaccg gtattattta cggagtggtt acgtgagaat aataatagca ttactgatgt
     1261 cattttttat tttacctgtt catgccggta tggtcatcta tggtacgcgc attatttatc
     1321 cgaaaaaaaa cagagaggtt ctcgtacagt taatgaatca aagtaaaaat gcctctttaa
     1381 ttcaggcatg gatcgatgat gggaacacca ctatcgcgcc agaaaaaatt caggtcctat
     1441 ttattctcac accgccagta agtcgtgtag caggtggttc cggccaacaa cttaaaataa
     1501 gaaaaatgcc aaacaatttg cctcacaata aagaaagctt attttatcta aatgttctgg
     1561 atatccctcc aaacaaccca caaaatgcag gaaagaacaa aattaaactt gcatttcaaa
     1621 accgtataaa gttactttgg cgtccaagcg gaatagctcc ggtagataaa aaaagccttt
     1681 ctcaattaaa tatcaaaaag aaaaataacg ccatctcaat aaacaacgaa acagccaact
     1741 ggataacggt tacaactatc aaagcacaaa acgtgaaagt taataatgaa agtatcttac
     1801 tgcctccatt ttcgaataac gacattacat taaaaaataa ccacgcatca gaatatgaac
     1861 taacggtagt tgatgattac gggaataaca tccatagtaa aatcgccgcg agataacagg
     1921 aaaaagtcat gttaaggacg acacgatggg tcgctgctat tatttttttg tattcttttc
     1981 cgggttatgc tgaagaaact tttgatacgc acttcatgat tggcggcatg agaggagaaa
     2041 aagtttccga atatcgtttc gataataaac aaccgcttcc aggaaactac gaacttgatt
     2101 tttatgtaaa tcaccagtgg cgtgggaaaa aagatatcac gatcccagag tcaccagcca
     2161 aaccatgtct gcctaaggtg ctgctaacca cactgggggt aaagaccgat aacctcaata
     2221 cagaagataa ttgtatttta ctggatgaag cggttcatgg tggacaatat cagtgggata
     2281 tcagtgaaca ccgactaaat ttaacgatcc cacaggcgta tatcaatgaa cttgaaagag
     2341 gttacgttcc cccggaaagt tgggatcgcg gcattgatgc tttttatacc tcctataatt
     2401 taagtcagta tcgctcttat gacagcaata ataacagtaa tacagccagt tatggccggt
     2461 tcaacagcgg attaaattta tttagttggc aattacactc tgatgccagc tatagcaaac
     2521 ctgatgatat gaaaggcaaa tggcaaagta atactcttta cctggaacgt ggctggtcgc
     2581 agatattaag cacagttcag ataggagaaa attacacatc ctcactcata ttcgactctc
     2641 tgcgatttag cggaatacgc ttatttcgcg atatgcaaat gctacctgat tctatgcaga
     2701 gctttacacc tttagtacaa ggtgttgcgc aaagtaatgc cttgataacg gtttcgcaaa
     2761 atggctacat catttaccaa aaagaggttc cccccgggcc atttactatc gcagatttgc
     2821 aactttcagg cagcggcgct gatctcgatg tcagcataaa ggaagcagat ggtagtgttc
     2881 gttccttttt ggtcccctac tcttccgtgc ccaacatgct gcaacctggt gtttcaaatt
     2941 tcgattttat cgccggacgc agtaagatat atggtgtaaa gaatcaggag gactttctcg
     3001 aggcaaatta tatatatggc ctcaacaatc ttttgacact ttatggcggt acgattttat
     3061 ccgataacta taatgctata actctgggaa atggttggaa tacaccgctg ggtgccatct
     3121 cttttgacgc tacccgatcg agtagtaagt taaataatga tataacacac gaaggtacga
     3181 gctatcaggt cgcctataat aaatatctag tgcaaacggc tactcgcttt agcgtggccg
     3241 cctggcgtta tgcttcgcag gattacagga cattcagcga ccatctttac gaaaatgata
     3301 aacacaatca tcagagtgaa tatgatgatt tttatgatat tggcagaaaa aatagccttt
     3361 ctgccaatat tatgcaacct ttatccaata atctgggaaa tgtatcatta agtgcgcttt
     3421 ggcggaatta ctgggggcga agtggaaatg ctaaagatta ccaattcagt tattccaata
     3481 gctggcaacg cattagttat actttctctg ccagccaatc ctatgatgaa aacgataaag
     3541 aagaggaacg ttttaatctg tttatctcca ttcctttcta ctggggggat gatattacca
     3601 aaacacgtca ccaaattaac ttatcgaatt cgacctcatt ttccaaagat ggctattcct
     3661 ccaacaatac tggagttact ggcatagccg gtgagcatga tcagttaaat tatggtatat
     3721 atgttaatca gcaacaacaa aataatgata cctcgcttgg tacgaattta agctggagaa
     3781 ctcccatcgc cataatagat ggcagctata gtcattctaa aaacacctgg caaagtggtg
     3841 gaagtattag tagtggatta gttgtctggc ccggtggtat taatatcact aaccagctat
     3901 ccgatacatt tgcaattctg gatgcgcctg ggttagaagg cgcacatatt aatggacaaa
     3961 aatacaaccg aacaaacagc aaaggccagg ttgtttacga cctgatgata cctcatcgtg
     4021 aaaaccatct ggtacttgat atagcaaaca gtgaaagtga aacagaattg cagggcaatc
     4081 gtcaaattat tgcgccttac cgtggagcag tttcttatgt gcagtttaca actgaccaac
     4141 gtaagccctg gtatatacag gcactgcgtc ccgatggttc gccattaacc tttggctatg
     4201 acgtactgga tctccaggaa aacaatattg gagtcgttgg ccagggtagt cgccttttta
     4261 ttcgcgtaga tgaaatcccc actggcataa aagttgctct caatgatgaa cagaacttat
     4321 tctgtactat tactttccaa cacgttatcg atgaaaacaa aacatatata tgccagtaaa
     4381 aggagtttac tatgaagtgg cttttattaa tcaccttgag tctatattct tttattgtgc
     4441 aaagtgctcc ctgtgcagtg accaatgtcg gtgaacaacg tggaacatat atactcaagc
     4501 cactaagtat gaaaggtaat ctaaccgccg aaaaaaatga aaacaccggg aatatcattg
     4561 agtgtgcaga cttgcaagag acgaccaacg ccattaaagt tcatttctta acacagaacg
     4621 ctttaaggtt taaagtcgga agtcgtcatt atattattaa ttttcccttt gaatctgacg
     4681 gtaaaaaaat agagcttcca gggaaggcat cttataattt agaagaaatg ctatctgcga
     4741 taaattttac cattccatat tctatcgcat ctgtacaaga tagttctaac accgcagaca
     4801 tttttccagg aactcctttt cctttgttgt tcgaaattga agtgagttca tgtacagg
//
LOCUS       DAPOAV010000181         4797 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.183, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000181 DAPOAV010000000
VERSION     DAPOAV010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4797
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.183"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            1..672
                     /gene="hprR"
                     /locus_tag="RN951_004375"
     CDS             1..672
                     /gene="hprR"
                     /locus_tag="RN951_004375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707854.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor HprR"
                     /protein_id="HDX2529263.1"
                     /translation="MKILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDD
                     YALIILDIMLPGMDGWQILQTLRTAKQTPVICLTARDSVDDRVRGLDSGANDYLVKPF
                     SFSELLARVRAQLRQHHALNSTLEISGLRMDSVSQSVSRDNISITLTRKEFQLLWLLA
                     SRAGEIIPRTVIASEIWGINFDSDTNTVDVAIRRLRAKVDDPFPEKLIATIRGMGYSF
                     VAVKK"
     gene            672..2030
                     /gene="hprS"
                     /locus_tag="RN951_004376"
     CDS             672..2030
                     /gene="hprS"
                     /locus_tag="RN951_004376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HprS"
                     /protein_id="HDX2529264.1"
                     /translation="MKRLSITVRLTLLFILLLSVAGAGIVWTLYNGLASELKWRDDTT
                     LINRTAQIKQLLIDGVNPDTLPVYFNRMMDVSQDILIIHGDGINKIVNRTNVSDDMLN
                     NIPASETISAAGIYRSIINDTEIDALRINIDEVSPSLTVTVAKLASARHNMLEQYKIN
                     SIIICIVAIVLCSVLSPLLIRTGLREIKKLSGVTEALNYNDSREPVEVSALPRELKPL
                     GQALNKMHQALVKDFERLSQFADDLAHELRTPINALLGQNQVTLSQTRSIAEYQKTIA
                     GNIEELENISRLTENILFLARADKNNVLVKLDSLSLNKEVENLLDYLEYLSDEKEICF
                     KVECNQQIFADKILLQRMLSNLIVNAIRYSPEKSRIHITSFLDTNSYLNIDIASPGTK
                     INEPEKLFRRFWRGDNSRHSVGQGLGLSLVKAIAELHGGSATYHYLNKHNVFRITLPQ
                     RN"
     gene            complement(2138..2989)
                     /gene="hchA"
                     /locus_tag="RN951_004377"
     CDS             complement(2138..2989)
                     /gene="hchA"
                     /locus_tag="RN951_004377"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein deglycase HchA"
                     /protein_id="HDX2529265.1"
                     /translation="MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKP
                     YRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMT
                     KFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIG
                     LPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTP
                     EIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKLLTGDSPFAANALGKLAAQE
                     MLAAYAG"
     gene            complement(3581..4774)
                     /gene="ompC"
                     /locus_tag="RN951_004378"
     CDS             complement(3581..4774)
                     /gene="ompC"
                     /locus_tag="RN951_004378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpC"
                     /protein_id="HDX2529266.1"
                     /translation="MKRKVLAMLVPALLVAGAANATEVYNKDGNKLDFYGKVAGLHYF
                     SDNSGADGDMSYARIGFKGETQIADQFTGYGQWEYNLQANGTEGDGDNSATRLAFAGL
                     GFGQNGTFDYGRNYGVVYDIEAWTDMLPEFGGDTYAGADNFMNGRTNGVATYRNNGFF
                     GQVDGLNFALQYQGNDKSGGPFGQEGSGSGDGRSLSKENGDGFGMSTSYDFDFGLSLG
                     AAYSNSDRSDRQVGVGLNDRNHSNRNAGGETAEAWTVGAKYDANNVYLAAMYAETRNM
                     TPYGGGEFDNGESRSAIANKTQNFEVVAQYQFDFGLRPSIAYLQSKGKDLGGWAHDGN
                     GDPRYTNKDLVKYVEVGATSYFNKNMSTYVDYKINLLDNDDDFYEANGIATDDIVAVG
                     LVYQF"
BASE COUNT         1332 a          996 c         1125 g         1344 t
ORIGIN      
        1 atgaagattt tacttattga agataatcaa aggacccagg agtgggtaac gcaggggctt
       61 tccgaagcgg gttatgtcat tgatgccgtt tctgatggca gagatgggct ttatcttgcg
      121 ctgaaggatg attatgcatt gatcattctg gatattatgc ttccgggtat ggatggctgg
      181 cagatcttac aaacgttaag aacagcaaag caaacccctg ttatttgcct tactgcaagg
      241 gattctgtcg atgacagagt cagagggctg gacagtggag caaatgatta tctggtaaaa
      301 cctttttcat tttctgagtt gctggcaagg gttcgggcac aattaaggca acatcacgct
      361 ttgaattcaa cattagaaat cagtggctta agaatggact ctgtaagtca aagtgtgagc
      421 agggacaata tcagcattac actgacgcgc aaggagtttc agttactttg gctactggcc
      481 tccagagctg gcgaaattat acccagaacg gttattgcga gtgaaatttg gggaatcaac
      541 tttgatagtg ataccaatac ggtggatgtc gccattcgca ggctccgcgc aaaagttgat
      601 gatccttttc ctgaaaagct aatcgccaca atccggggga tgggctattc attcgtagcg
      661 gtaaaaaaat aatgaaaaga ttatctataa ccgtccgttt aaccttgctt tttatattgc
      721 tgctgtctgt tgctggcgct ggaattgtct ggactctcta taatggcctg gcaagtgagt
      781 tgaaatggcg cgatgataca acactcatta accggacagc acagatcaag cagttgttaa
      841 ttgatggggt aaatccagat acgttacctg tatactttaa ccggatgatg gatgttagtc
      901 aggatatctt gatcattcat ggtgatggca tcaataaaat tgttaaccgg acaaatgtca
      961 gtgatgacat gttaaataac atacctgcta gtgagacaat cagcgcagct ggcatttaca
     1021 gaagcattat taatgacact gagattgatg ctttacgaat taatattgat gaagtttcgc
     1081 catcattgac ggttactgtg gctaaattgg cttcagccag acataacatg cttgaacagt
     1141 ataaaattaa tagcattata atttgcattg tcgccattgt actttgctca gtattaagtc
     1201 cgctgttaat cagaacggga ttacgagaga tcaaaaagtt gagtggtgta acggaagcgc
     1261 tgaattataa cgatagccgg gagcctgttg aggttagcgc attaccgaga gaactaaaac
     1321 ctcttgggca ggcgttgaat aaaatgcatc aagccttagt caaagatttt gaacgcctaa
     1381 gtcaatttgc tgacgatctc gctcatgaac ttagaacgcc aattaatgca ttactgggtc
     1441 agaatcaggt tacgctcagt caaaccagaa gtatcgctga atatcaaaaa acaattgccg
     1501 gtaacattga agagctggaa aatatttcgc ggttaacaga gaacatactg tttcttgcca
     1561 gggcagataa aaacaatgtt ttggtgaaac tggactcgct ttctctcaat aaggaagtcg
     1621 aaaatttgtt ggactatctt gaatatcttt cagacgagaa agagatttgc tttaaggtcg
     1681 agtgcaatca gcaaatcttt gcggataaaa ttttactgca acgaatgtta tcgaatctta
     1741 ttgttaacgc cattagatat tcgccagaaa aatcgcgtat tcatataacc agttttcttg
     1801 ataccaacag ctatcttaat attgatatcg ccagccctgg aacgaaaatt aatgagcctg
     1861 aaaaactctt ccgtagattt tggcggggag ataattcgcg tcattccgta ggtcagggac
     1921 ttggtctttc tttagtcaaa gcgattgccg aattacatgg gggaagtgct acgtatcact
     1981 atctcaataa gcataatgtg ttccggatta cgttgccgca aagaaattaa catagggctt
     2041 cagtacgcca taaattaacc gtgaaaaaac gcagccacgt cgtgaatact aacgcggctg
     2101 cgattgatta tgcgcttaca ttaaaacgta acagggatta acccgcgtaa gctgccagca
     2161 tttcctgcgc cgccagttta cccaacgcat tcgctgcgaa aggactgtcg ccggtgagaa
     2221 gtttacggtc cttatgtact cgcccggtga tgtcgtcatt aatgatgttc atgcccattt
     2281 tcttcagttc ttcgccgaag taccaggtga gatgacccgg catatagcct atctctggcg
     2341 tttgtttgtc agcggcgtct gggaatgcac aaatggaata accattcagt gggttatcgc
     2401 cgtggcgaag cgccagaaaa gccgccgggc cgtggcaaag ggagataaca aaacggtcat
     2461 ttttgattgc ccactgtaaa gcagcagcca cgtcctggct ttctggtaaa ccaataagtg
     2521 cgccatgacc accaggaaca aagattgctg catattcgct atcagcgttg aggctggcga
     2581 caacatccgc gagtttcttc ggattgcgga acaacgattt atgctgctca aagaatggca
     2641 ttactttttc atctttgtgc ggcatagccc agtattcaaa cttggtcatc agaccggaaa
     2701 tggtcgccac ttcgaattcg aaacctgcag catggagatg atacaacggc agcaacgttt
     2761 caatcggatg gttaccagtc gagaacagtt ttccgttatc ggtcggcaaa taacgttcgt
     2821 ccgcggcgat caccagaatt ttatgcttac cgcgatacgg ttttggatag tccacgccat
     2881 caagatcaga gacgggactg gtatattggc taagcgaata ttctgaaggg aagaatgcat
     2941 tatcttcagc aatatcgacc tgcggatttt tacttgtttg aacagtcata gtgtattcct
     3001 tattgttgct tagttagggt ggtcactata tttgcgactg agctggtcgc tatttttaac
     3061 caggctggaa aattgagtca atatatcgaa agcggtagtc ggcgggtgta agtatgtaat
     3121 gatgatgctt cactggtgtt gaatattatt cacgccaaat tttccttatt gagcaacgtc
     3181 gtcgcaagtg gcctcaatga ttttagacca ttatcagagg tacggggcgg cggggagaga
     3241 tttagtgctg tggaatattg tggtgctgat gaatatttat atcccggatt ggtggagaaa
     3301 aagctttttc catgcacttt ttttgcaaat atttctatat gggaagcgtg tttgttacgg
     3361 attaattcat aaagaaatgc atttgggtgt tggcttgaag agtcactggt tgatgttatt
     3421 gtgccaggag gggcagggta agggggtgta tcgataagct ttggcaattg cgtgtgccgc
     3481 agatggagat gaaatgccaa taaaaaagcc tgagttcgat gagggacgaa ctcaggctag
     3541 tgttaagttt tacagtaaca cgccgcggcg tgttggctga ttagaactgg tagactaagc
     3601 ccacagccac gatatcatcg gtagcgatgc cgtttgcttc gtagaagtca tcgtcgttgt
     3661 ccagcaggtt gattttgtaa tcaacgtagg tggacatgtt tttgttgaag taggaggtcg
     3721 caccgacttc aacgtattta accagatctt tgttggtgta acgcggatcg ccattaccgt
     3781 catgagccca accgcctaaa tccttacctt tagattgcag gtaagcgatg gacgggcgca
     3841 ggccaaagtc gaactgatac tgagcaacaa cttcaaagtt ttgggttttg ttagcgatgg
     3901 ctgatcttga ttcaccatta tcaaactcgc caccaccata tggggtcata ttgcgagttt
     3961 cagcgtacat agctgctaaa tacacattat tagcatcata ttttgcacca acagtccatg
     4021 cttcagcggt ttcaccacca gcatttctgt tgctatggtt acgatcattt aaaccaactc
     4081 caacctgacg atctgaacga tcagagtttg aatatgcagc acccagactt aaaccgaagt
     4141 cgaagtcgta ggatgttgac ataccgaaac catcaccatt ttctttggaa aggctacggc
     4201 catcaccact accggaacct tcctgcccga atggtccacc acttttatca ttaccctgat
     4261 attgcaaagc aaagttcaag ccatcaacct gaccaaagaa gccattgtta cggtaggttg
     4321 caacaccgtt ggtacgaccg ttcatgaagt tgtcggcacc cgcgtaggta tcgccaccaa
     4381 attctggcag catatcggtc catgcttcga tgtcatatac gacaccgtag ttacgaccat
     4441 aatcgaaagt accattctga ccaaaaccta aacctgcgaa tgccagacgg gtagcagagt
     4501 tatctccatc gccttctgtg ccatttgctt gcaggttgta ttcccactga ccgtaaccag
     4561 tgaactggtc agcgatttgt gtttcgcctt tgaaaccgat acgggcatat gacatatcgc
     4621 catcagcgcc cgagttgtca gagaagtagt gcagacctgc tacttttccg tagaaatcca
     4681 gtttattacc atctttatta tagacttcag tcgcatttgc tgcgccagca actaataacg
     4741 ccgggaccag cattgccaga acttttcttt tcattatgta ttcccttgtg attataa
//
LOCUS       DAPOAV010000182         4789 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.184, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000182 DAPOAV010000000
VERSION     DAPOAV010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4789
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.184"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..575)
                     /locus_tag="RN951_004379"
     CDS             complement(<1..575)
                     /locus_tag="RN951_004379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDX2529267.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     RAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQ
                     YDFPGDDTPIVRGSALKALEGDAEWEAKILEL"
     gene            complement(690..765)
                     /locus_tag="RN951_004380"
     tRNA            complement(690..765)
                     /locus_tag="RN951_004380"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(730..732),aa:Thr,seq:ggt)
     gene            complement(772..846)
                     /locus_tag="RN951_004381"
     tRNA            complement(772..846)
                     /locus_tag="RN951_004381"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(811..813),aa:Gly,seq:tcc)
     gene            complement(963..1047)
                     /locus_tag="RN951_004382"
     tRNA            complement(963..1047)
                     /locus_tag="RN951_004382"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1011..1013),aa:Tyr,seq:gta)
     gene            complement(1056..1131)
                     /locus_tag="RN951_004383"
     tRNA            complement(1056..1131)
                     /locus_tag="RN951_004383"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1096..1098),aa:Thr,seq:tgt)
     gene            1493..2443
                     /gene="coaA"
                     /locus_tag="RN951_004384"
                     /gene_synonym="panK"
     CDS             1493..2443
                     /gene="coaA"
                     /locus_tag="RN951_004384"
                     /gene_synonym="panK"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HDX2529268.1"
                     /translation="MSIKEQTLMTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINE
                     DLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKS
                     TTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFV
                     SDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVF
                     VSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMT
                     LWKEINWLNLKQNILPTRERASLILTKSANHAVEEVRLRK"
     gene            complement(2472..3437)
                     /locus_tag="RN951_004385"
     CDS             complement(2472..3437)
                     /locus_tag="RN951_004385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HDX2529269.1"
                     /translation="MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLR
                     DWGVDVFTVPGKGYSLPEPIQLLNAKQILGQLDGGSVAVLPVIDSTNQYLLDRIGELK
                     SGDACIAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEV
                     LRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESV
                     VNQGWITLQEAGINLDRNTLAAMLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPV
                     KLIIGDKEIFGISRGIDKQGALLLEQDGIIKPWMGGEISLRSAEK"
     gene            complement(3434..4462)
                     /gene="murB"
                     /locus_tag="RN951_004386"
     CDS             complement(3434..4462)
                     /gene="murB"
                     /locus_tag="RN951_004386"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HDX2529270.1"
                     /translation="MNHSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQYATAEGQPVL
                     ILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLHVGAGENWHRLVKYTLQEGMP
                     GLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDSVELATGKQVRLTAKECRFGYRD
                     SIFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLDPTTVTPQQVFNAVCHMRTTKL
                     PDPKVNGNAGSFFKNPVVSAETAKALLSQFPTAPNYPQADGSVKLAAGWLIDQCQLKG
                     MQIGGAAVHRQQALVLINEDNAKSEDVVQLAHHVRQKVGEKFNVWLEPEVRFIGASGE
                     VSAVETIS"
BASE COUNT         1213 a         1216 c         1086 g         1274 t
ORIGIN      
        1 agttccagga ttttcgcttc ccactctgcg tcgccttcca gcgctttcag agcagaacca
       61 cgaacgatcg gagtgtcgtc gcccgggaag tcgtactgag acagaagttc acgaacttcc
      121 atttcaacca gttccagcag ctcttcgtca tcaaccatgt cgcatttgtt caggaacacg
      181 atgatgtacg gaacgcctac ctgacgaccc agcaggatgt gctcacgagt ctgcggcatc
      241 gggccgtcag tcgcagcaac taccaggatc gcgccgtcca tctgcgcagc accggtgatc
      301 atgtttttaa catagtcggc gtgccccggg cagtctacgt gtgcgtagtg acgggtcggg
      361 gtgtcgtatt caacgtgaga agtgttgatg gtgataccac gagctttttc ttccggcgcg
      421 ttatcgatct ggtcgaatgc gcgagcagca ccgccgtagg ttttagccag tacggtagtg
      481 attgcagcgg tcagcgttgt tttaccatgg tcaacgtggc cgatagtacc gacgttaacg
      541 tgcggttttg tacgttcaaa cttttcttta gacatcgatt gtccctctaa gacacggata
      601 aatcggtgat atcaccacat caaccaggca acatgcccga cttgttgaat gcaataaaca
      661 gaaggaaaaa acagggagga gaaaagaagt ggtgctgata ggcagattcg aactgccgac
      721 ctcaccctta ccaagggtgc gctctaccaa ctgagctata tcagcacatc ttggagcggg
      781 cagcgggaat cgaacccgca tcatcagctt ggaaggctga ggtaatagcc attatacgat
      841 gcccgcatcc tggaactcgg ctacctgatt ttcattctgc actgaatatc gagagaagct
      901 ctctttattc gagccggtaa gcgaacttat cgtctcgggc tacgccatcg cgtggccgaa
      961 attggtggtg ggggaaggat tcgaaccttc gaagtctgtg acggcagatt tacagtctgc
     1021 tccctttggc cgctcgggaa ccccaccgga cttgatggtg ccgactaccg gaatcgaact
     1081 ggtgacctac tgattacaag tcagttgctc tacctactga gctaagtcgg catcaagtag
     1141 cgcgcattct atggagacat gcgagttcat gcaactaaaa aattgcataa tttgttttat
     1201 tggtcacatt ttatgcgaca cgatgaagaa acagccgaac ggagggcaga ttagcacact
     1261 ttttcaacat cattgtgctc aacaatgcgc tcctgctaaa ccataattct ttttatcaga
     1321 tggaatatct gtcacattgc ttttcaacga tagcttcctg gcagagattt tttcttatta
     1381 ttcctcccca tctggtgtta ccctcctgcc cattaaccca ttcaacagaa ctgtgacgcg
     1441 ccatggcaaa tatcgctttg ccgatagagc tatgaccgcc agaaacatgc ttatgagtat
     1501 aaaagagcaa acgttaatga cgccttacct acagtttgac cgcaaccagt gggcagctct
     1561 gcgtgattcc gtacctatga cgttatcgga agatgagatc gcccgtctca aaggtattaa
     1621 tgaagatctc tcgttagaag aagttgccga gatctattta cctttgtcac gtttgctgaa
     1681 cttctatata agctcgaatc tgcgccgtca ggcagttctg gaacagtttc ttggtaccaa
     1741 cgggcaacgc attccttaca ttatcagtat tgctggcagt gtcgcggtgg ggaaaagtac
     1801 aaccgcccgt gtattgcagg cgctattaag ccgttggccg gaacatcgtc gtgttgaact
     1861 gatcactaca gatggcttcc ttcaccctaa tcaggttctg aaagaacgtg gtctgatgaa
     1921 gaagaaaggc ttcccggaat cgtatgatat gcatcgcctg gtgaagtttg tttccgatct
     1981 caaatccggc gtgccaaacg ttacagcacc tgtttactca catcttattt atgatgtgat
     2041 cccggatgga gataaaacgg ttgttcagcc tgatatttta attcttgaag ggttaaatgt
     2101 cttacagagc gggatggatt atccacacga tccacatcat gtatttgttt ctgattttgt
     2161 cgatttttcg atatatgttg atgcaccgga agacttactt cagacatggt atatcaaccg
     2221 ttttctgaaa ttccgcgaag gggcttttac cgacccggat tcctattttc ataactacgc
     2281 gaaattaact aaagaagaag cgattaagac tgccatgaca ttgtggaaag agatcaactg
     2341 gctgaactta aagcaaaata ttctacctac tcgtgagcgc gccagtttaa tcctgacgaa
     2401 aagtgctaat catgcggtag aagaggtcag actacgcaaa taatttgcag gggagcgaat
     2461 actccccttt cttatttttc tgcactacgc agggatattt caccgcccat ccagggtttt
     2521 attattccat cctgctcaag taataaagcc ccctgtttgt ctattccgcg tgaaatgcca
     2581 aatatttctt tatcaccaat gataagtttc actgggcgat taataaaatt atccagcttt
     2641 tcccagcgcg acagataagg tgccaatcct tcttgttcga agagttccaa cgcagcacgt
     2701 aattcacgta ttagcatggc cgccaacgta ttacgatcga gattgatccc cgcttcctgc
     2761 agcgtgatcc acccctgatt aacgacactc tcttcaacac ggcgcattgc catgttgatc
     2821 ccggctccaa tgactatttg cgccgcatcg ccagttttgc cagtcagctc cacaagaatg
     2881 cctgccagct tgcgatcctg cagatagagg tcattaggcc atttaacacg aactttatct
     2941 gcacccagct tgcgtaatac ttccgccatc acgataccga taaccagact taaaccaatc
     3001 gccgccgccg ggccttgttc cagacgccag aacatcgaca aatataagtt tgcgccaaaa
     3061 ggcgaaaacc atttccgacc ccggcgacca cggccagcct gctggtattc tgcaatgcaa
     3121 gcatcgcccg atttaagctc tccgatacga tcaagaaggt actgattcgt ggagtcaatc
     3181 actggcagca cggctacact accgccatcc agctgaccca atatctgttt agcattaagt
     3241 aactggatag gctcaggcag gctgtatcct ttacccggaa cggtaaagac atcaacgccc
     3301 cagtcacgca gtgtctgaat gtgtttatta atagccgccc ggctcattcc cagcgtttca
     3361 cccaactgct cgccagagtg aaattcaccg ttcgctaaca gggcaatcaa tttcagtggc
     3421 acggtgttat ccttcatgaa attgtctcca ctgcgctcac ttcacctgat gcaccaataa
     3481 agcggacttc aggctcaagc cagacattaa atttttcacc aactttctgt cttacatgat
     3541 gcgccagctg tacaacatct tcgctttttg cattgtcttc attaatgaga actaacgcct
     3601 gttgacggtg caccgcagcc ccacctattt gcatcccttt tagctggcac tgatcgataa
     3661 gccaacctgc tgccagtttt actgaaccat ccgcctgggg gtaatttggt gctgttggaa
     3721 attgtgacag taatgcttta gccgtttcgg cagatacaac agggtttttg aagaaactac
     3781 cggcattgcc attcactttt ggatcaggga gtttggtggt gcgcatatga cacaccgcat
     3841 taaatacttg ctgtggcgtt actgttgtag gatccagacg agttaagtca ccatacgtta
     3901 gtacaggttg ccactctttt ggcagacgca gacctacggc tacaatagcg aagcggtcct
     3961 ggtattcatg tttaaaaata ctgtcgcgat agccaaaacg gcactctttg gcagttaagc
     4021 gcacttgctt gcctgtcgcc agttcaacag aatcaacata agcgcaaact cgctgtaatt
     4081 ctacgccata agcaccaata ttctggatag gtgatgagcc gacacaacca ggaattaatg
     4141 ccagattttc cagaccaggc ataccttcct gcaaagtgta ttttaccaga cgatgccagt
     4201 tttctccggc tcctacatgt aaataccacg catcaggttc atcatgaatt tcgatacctt
     4261 tgatccggtt gatgatcacc gtgccgcgat agtcctccag aaaaagtaca ttacttcctt
     4321 cacccagaat aagaacgggt tgtccttctg cggttgcata ctgccaggca ttgagtaatt
     4381 gttgttcgtc ttcggcacat acaatgtgct gagcattatg atcaatgcca aatgtgttcc
     4441 agggttttaa ggagtggttc atagctgctt tcctgatgca aaaacgaggc tagtttaccg
     4501 tatctgtggg gggatggctt gtagatatga cgacaggaag agtttgtaga aacgcaaaaa
     4561 ggccatccgt caggatggcc ttctgcttaa tttgatgcct ggcagtttat ggcggcgtcc
     4621 tgcccgccac cctccgggcc gttgcttcgc aacgttcaaa tccgctcccg gcggatttgt
     4681 cctactcagg agagcgttca ccgacaaaca acagataaaa cgaaaggccc agtctttcga
     4741 ctgagccttt cgttttattt gatgcctggc agttccctac tctcgcatg
//
LOCUS       DAPOAV010000183         4731 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.185, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000183 DAPOAV010000000
VERSION     DAPOAV010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4731
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.185"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..965
                     /locus_tag="RN951_004387"
     CDS             <1..965
                     /locus_tag="RN951_004387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031587700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1380-like element ISEc9 family transposase"
                     /protein_id="HDX2529271.1"
                     /translation="FKTTQMFRDINFKVFKKLLTKSKLTSITIDIDSSVINVEGHQEG
                     ASKGYNPKKLGNRCYNIQFAFCDELKAYVTGFVRSGNTYTANGAAEMIKEIVANIKSD
                     DLEILFRMDSGYFDEKIIETIESLGCKYLIKAKSYSTLTSQATNSSIVFVKGEEGRET
                     TELYTKLVKWEKDRRFVVSRVLKPEKERAQLSLLEGSEYDYFFFVTNTTLLSEKVVIY
                     YEKRGNAENYIKEAKYDMAVGHLLLKSFWANEAVFQMMMLSYNLFLLFKFDSLDSSEY
                     RQQIKTFRLKYVFLAAKIIKTARYVIMKLSENYPYKGVYEKCLV"
     gene            1221..2096
                     /locus_tag="RN951_004388"
     CDS             1221..2096
                     /locus_tag="RN951_004388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011091028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A extended-spectrum beta-lactamase
                     CTX-M-15"
                     /protein_id="HDX2529272.1"
                     /translation="MVKKSLRQFTLMATATVTLLLGSVPLYAQTADVQQKLAELERQS
                     GGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKK
                     SDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPASVTAFARQLGD
                     ETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRAQLVTWMKGNT
                     TGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQPQPKAESR
                     RDVLASAAKIVTDGL"
     gene            complement(2143..2475)
                     /locus_tag="RN951_004389"
     CDS             complement(2143..2475)
                     /locus_tag="RN951_004389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001393253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WbuC family cupin fold metalloprotein"
                     /protein_id="HDX2529273.1"
                     /translation="MRPHRHPHTFELLLPLRGRFVVLNFDDRGTVTHRAILGETCTVL
                     EMAAGTWHAVLSLDTGGIIFEVKHGGYQPVAADDYAHWAPAEGEPGTTELMAWYAQAQ
                     VGDSTFAV"
     gene            2489..4731
                     /locus_tag="RN951_004390"
                     /pseudo
     CDS             2489..4731
                     /locus_tag="RN951_004390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
BASE COUNT         1289 a         1085 c         1193 g         1164 t
ORIGIN      
        1 acttcaagac aacccaaatg tttagagaca ttaattttaa agtctttaaa aaactgctca
       61 ctaaaagtaa attgacatcc attacgattg atattgatag tagtgtaatt aacgtagaag
      121 gtcatcaaga aggtgcgtca aaaggatata atcctaagaa actgggaaac cgatgctaca
      181 atatccaatt tgcattttgc gacgaattaa aagcatatgt taccggattt gtaagaagtg
      241 gcaatactta cactgcaaac ggtgctgcgg aaatgatcaa agaaattgtt gctaacatca
      301 aatcagacga tttagaaatt ttatttcgaa tggatagtgg ctactttgat gaaaaaatta
      361 tcgaaacgat agaatctctt ggatgcaaat atttaattaa agccaaaagt tattctacac
      421 tcacctcaca agcaacgaat tcatcaattg tattcgttaa aggagaagaa ggtagagaaa
      481 ctacagaact gtatacaaaa ttagttaaat gggaaaaaga cagaagattt gtcgtatctc
      541 gcgtactgaa accagaaaaa gaaagagcac aattatcact tttagaaggt tccgaatacg
      601 actacttttt ctttgtaaca aatactacct tgctttctga aaaagtagtt atatactatg
      661 aaaagcgtgg taatgctgaa aactatatca aagaagccaa atacgacatg gcggtgggtc
      721 atctcttgct aaagtcattt tgggcgaatg aagccgtgtt tcaaatgatg atgctttcat
      781 ataacctatt tttgttgttc aagtttgatt ccttggactc ttcagaatac agacagcaaa
      841 taaagacctt tcgtttgaag tatgtatttc ttgcagcaaa aataatcaaa accgcaagat
      901 atgtaatcat gaagttgtcg gaaaactatc cgtacaaggg agtgtatgaa aaatgtctgg
      961 tataataaga atatcatcaa taaaattgag tgttgctctg tggataactt gcagagttta
     1021 ttaagtatca ttgcagcaaa gatgaaatca atgatttatc aaaaatgatt gaaaggtggt
     1081 tgtaaataat gttacaatgt gtgagaagca gtctaaattc ttcgtgaaat agtgattttt
     1141 gaagctaata aaaaacacac gtggaattta gggactattc atgttgttgt tatttcgtat
     1201 cttccagaat aaggaatccc atggttaaaa aatcactgcg ccagttcacg ctgatggcga
     1261 cggcaaccgt cacgctgttg ttaggaagtg tgccgctgta tgcgcaaacg gcggacgtac
     1321 agcaaaaact tgccgaatta gagcggcagt cgggaggcag actgggtgtg gcattgatta
     1381 acacagcaga taattcgcaa atactttatc gtgctgatga gcgctttgcg atgtgcagca
     1441 ccagtaaagt gatggccgcg gccgcggtgc tgaagaaaag tgaaagcgaa ccgaatctgt
     1501 taaatcagcg agttgagatc aaaaaatctg accttgttaa ctataatccg attgcggaaa
     1561 agcacgtcaa tgggacgatg tcactggctg agcttagcgc ggccgcgcta cagtacagcg
     1621 ataacgtggc gatgaataag ctgattgctc acgttggcgg cccggctagc gtcaccgcgt
     1681 tcgcccgaca gctgggagac gaaacgttcc gtctcgaccg taccgagccg acgttaaaca
     1741 ccgccattcc gggcgatccg cgtgatacca cttcacctcg ggcaatggcg caaactctgc
     1801 ggaatctgac gctgggtaaa gcattgggcg acagccaacg ggcgcagctg gtgacatgga
     1861 tgaaaggcaa taccaccggt gcagcgagca ttcaggctgg actgcctgct tcctgggttg
     1921 tgggggataa aaccggcagc ggtggctatg gcaccaccaa cgatatcgcg gtgatctggc
     1981 caaaagatcg tgcgccgctg attctggtca cttacttcac ccagcctcaa cctaaggcag
     2041 aaagccgtcg cgatgtatta gcgtcggcgg ctaaaatcgt caccgacggt ttgtaatagc
     2101 ggaaacggaa tggggaaact cattccgttt ttgtttatcg ccttagacgg caaaagtgct
     2161 gtcgcccacc tgcgcttgcg cataccaggc cataagctcc gtggttcctg gttctccttc
     2221 cgctggagcc cagtgcgcat agtcatcggc agccacgggt tgatagccac cgtgttttac
     2281 ttcaaaaatt atgccaccgg tatccagcga cagcacggca tgccaggttc ctgcggccat
     2341 ctccagcacc gtacaggttt cccccaatat cgcccgatgg gtgacggtac cccgatcgtc
     2401 aaaattcagc accacgaaac gaccccttaa tggcaacagt agctcgaagg tgtgagggtg
     2461 tcggtgcggg cgcacgtagg tcccaggtca tattccttcc ggcgtccggc attttaccgc
     2521 cagacagctc gggattcgtg atatcaccgt tcttgcagaa tacggtcaga gggaaaatac
     2581 ccgccgtgag catgcagcgc tgatacgtca gcactatcag tatcgtgaat ttgcctggcc
     2641 ctggacattt cgccttaccc gtcttttata tacccggagc tggataagca acgaacgtcc
     2701 tggcctgctt ttcgatctgg cgacagggtg gcttatgcaa catcgtatta ttctccccgg
     2761 agccactacg ctgatccggt tgatttcaga ggtaagggaa aaggcgacgt tgcgcctgtg
     2821 gaacaaactg gcactgatac cgtcagccga acagcgttca cagctggaga tgctgctggg
     2881 gccaactgat tgcagccgcc tgtctttact ggaatcactg aaaaagggcc ctgtgaccat
     2941 cagtggtccg gcgtttaatg aagcaattga acgctggaaa actctgaacg attttggcct
     3001 gcatgctgaa aacctgagta cactcccggc tgtgcgcctg aaaaatctcg cacgttatgc
     3061 tggtatgact tcggtgttca atattgccag gatgtcaccg cagaaaagga tggcggttct
     3121 ggttgccttt gtccttgcat gggaaacgct ggcgctggat gatgcattgg acgttctgga
     3181 cgccatgctg gccgttatca tccgtgacgc cagaaagatt gggcagaaaa aacggctccg
     3241 ctcgctgaag gatctggata aatctgcatt ggcgctcgcc agcgcatgtt cgtacctgct
     3301 gaaagaagaa acaccggacg aatcgattcg tgctgaggtg ttcagctaca tcccaaggca
     3361 aaagctggct gaaatcatca cgcttgtccg tgaaattgcc cggccctcag acgataattt
     3421 tcatgaagaa atggtggagc agtacgggcg cgttcgtcgt ttcctgcccc atctgctgaa
     3481 taccgttaaa ttttcatccg cacctgccgg ggttaccact ctgaatgcct gtgactacct
     3541 cagccgggag ttcagctcac ggcggcagtt ttttgacgac gcaccaacgg aaattatcag
     3601 tcggtcatgg aaacggctgg tgattaacaa ggaaaaacat atcacccgca ggggatacac
     3661 gctctgcttt ctcagtaaac tgcaggatag tctgaggcgg agggatgtct acgttaccgg
     3721 cagtaaccgg tggggagatc ctcgtgcaag attactacag ggtgctgact ggcaggcaaa
     3781 ccggattaag gtttatcgtt ctttggggca cccgacagac ccgcaggaag caataaaatc
     3841 tctgggtcat cagcttgata gtcgttacag acaggttgct gcacgtcttt gcgaaaatga
     3901 ggctgtcgaa ctcgatgttt ctggcccgaa gccccggttg acaatttctc ccctcgccag
     3961 tcttgatgag ccggacagtc tgaaacgact gagcaaaatg atcagtgatc tactccctcc
     4021 ggtggattta acggagttgc tgctcgaaat taacgcccat accggatttg ctgatgagtt
     4081 tttccatgct agtgaagcca gtgccagagt tgatgatctg cccgtcagca tcagcgccgt
     4141 gctgatggct gaagcctgca atatcggtct ggaaccactg atcagatcaa atgttcctgc
     4201 actgacccga caccggctga actggacaaa agcgaactat ctgcgggctg aaactatcac
     4261 cagcgctaat gccagactgg ttgattttca ggcaacgctg ccactggcac agatatgggg
     4321 tggaggagaa gtggcatctg cagatggaat gcgctttgtt acgccagtca gaacaatcaa
     4381 tgccggaccg aaccgcaaat actttggtaa taacagaggg atcacctggt acaactttgt
     4441 gtccgatcag tattccggct ttcatggcat cgttataccg gggacgctga gggactctat
     4501 ctttgtgctg gaaggtcttc tggaacagga gaccgggctg aatccaaccg aaattatgac
     4561 cgatacagca ggtgccagcg aacttgtctt tggccttttc tggctgctgg gataccagtt
     4621 ttctccacgc ctggctgatg ccggtgcttc ggttttctgg cgaatggacc atgatgccga
     4681 ctatggcgtg ctgaatgata ttgccagagg gcaatcagat ccccgaaaaa t
//
LOCUS       DAPOAV010000184         4636 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.187, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000184 DAPOAV010000000
VERSION     DAPOAV010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4636
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.187"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..190)
                     /locus_tag="RN951_004391"
     CDS             complement(<1..190)
                     /locus_tag="RN951_004391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529274.1"
                     /translation="MKLIIFILIVLIIAALLIRIILRSVNQHSPLLMQLHAAGIRTGD
                     AERILSGGEYWQRQKTLLT"
     gene            complement(228..437)
                     /gene="hha"
                     /locus_tag="RN951_004392"
     CDS             complement(228..437)
                     /gene="hha"
                     /locus_tag="RN951_004392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="HDX2529275.1"
                     /translation="MAKTKQEWLYQLRRCSSVNTLEKIIHKNRDSLLNSERESFNSAA
                     DHRLAELITGKLYDRIPKEIWKYVR"
     gene            complement(483..944)
                     /locus_tag="RN951_004393"
     CDS             complement(483..944)
                     /locus_tag="RN951_004393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="HDX2529276.1"
                     /translation="MRKYIPLVLFIFSWPVLCADIHGRVVRVLDGDTIEVMDSRKAVR
                     IRLINIDAPEKKQDYGRWSTDMMKSLVAGKTVTVTYFQRDRYGRILGQVYAPDGMNVN
                     QFMVRAGAAWVYEQYNTDPVLPVLQNEARQQKRGLWSDADPVPPWIWRHRK"
     gene            complement(1189..1401)
                     /locus_tag="RN951_004394"
     CDS             complement(1189..1401)
                     /locus_tag="RN951_004394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001369432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANR family transcriptional regulator"
                     /protein_id="HDX2529277.1"
                     /translation="MNGTGRDSQNSGVWRYRQVGRRAVRLEVRGDWPGAAEAWLRAAQ
                     SAPRTDWQQFARKRAEHCHRRCRGRV"
     gene            complement(1530..2090)
                     /locus_tag="RN951_004395"
     CDS             complement(1530..2090)
                     /locus_tag="RN951_004395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fertility inhibition protein FinO"
                     /protein_id="HDX2529278.1"
                     /translation="MTEQKRPVLTLKRKTEGETPTRSRKTIINVTTPPKWKVKKQKLA
                     EKAAREAELTAKKAQARQALSIYLNLPTLDEAVNTLKPWWPGLFDGDTPRLLACGIRD
                     VLLEDVAQRNIPLSHKKLRRALKAITRSESYLCAMKAGACRYDTEGYVTEHISQEEEV
                     YAAERLDKIRRQNRIKAELQAVLDEQ"
     gene            complement(2193..3053)
                     /locus_tag="RN951_004396"
     CDS             complement(2193..3053)
                     /locus_tag="RN951_004396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDX2529279.1"
                     /translation="MKITDHKLSEGIALTFRVPEGNIKHPLIILCHGFCGIRNVLLPC
                     FANAFTEAGFATITFDYRGFGESDGERGRLVPAMQTEDIISVINWAEKQECIDNQRIG
                     LWGTSLGGGHVFSAAAQDQRVKCIVSQLAFADGDVLVTGEMNESERASFLSTLNKMAE
                     KKKNTGKEMFVGVTRVLSDNESKVFFEKVKGQYPEMDIKIPFLTVMETLQYKPAESAA
                     KVQCPVLIVIAGQDSVNPPEQGKALYDAVASGTKELYEEADACHYDIYEGAFFERVAA
                     VQTQWFKKHL"
     gene            complement(3112..3858)
                     /gene="traX"
                     /locus_tag="RN951_004397"
     CDS             complement(3112..3858)
                     /gene="traX"
                     /locus_tag="RN951_004397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858383.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer pilus acetylase TraX"
                     /protein_id="HDX2529280.1"
                     /translation="MTTDNTNTTRNDSLAARTDTWLQSFLVWSPGQRDIIKTVALVLM
                     VLDHINLIFQLKQEWMFLAGRGAFPLFALVWGLNLSRHAHIRQPAINRLWGWGIIAQF
                     AYYLAGFPWYEGNILFAFAVAAQVLTWCETRSGWRTAAAILLMALWGPLSGTSYGIAG
                     LLMLAVSYRLYRAEDRAERLALLACLLAVIPALNLASSDAAAVAGLVMTVLTVGLVSC
                     AGKSLPRFWPGDFFPVFYACHLAVLGVLAL"
     gene            complement(3878..>4636)
                     /locus_tag="RN951_004398"
     CDS             complement(3878..>4636)
                     /locus_tag="RN951_004398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001463032.1"
                     /note="cleaves origin of transfer and unwinds; oriT
                     relaxase; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative transfer relaxase/helicase TraI"
                     /protein_id="HDX2529281.1"
                     /translation="GLAGGDSPARFIAPGRKYPQPYVALPAFDRNGKSAGIWLNPLTT
                     DDGNGLRGFSGEGRVKGSGDAQFVALQGSRNGESLLADNMQDGVRIARDNPDSGVVVR
                     IAGEGRPWNPGAITGGRVWGDIPDSSVQPGAGNGEPVTAEVLAQRQAEEAIRRETERR
                     ADEIVRKMAENKPDLPDGKTEQAVREIAGQERDRADITEREAALPESVLRESQREQEA
                     VREVARENLLQERLQQIERDMVRDLQKEKTLGGD"
BASE COUNT         1067 a         1353 c          995 g         1221 t
ORIGIN      
        1 ctgtcagcag cgtcttctga cgttgccagt attcaccgcc ggacagtatt cgctctgcat
       61 caccggtccg tatacctgcc gcatgcaatt gcatcagcaa aggagaatgc tgatttacac
      121 ttctgaggat aatccggata agtaacgctg caataatcag aacaataaga ataaaaataa
      181 tcagcttcat tgtttatctg ctcctggtaa ttaattatgc tgaattatta ccttacatat
      241 ttccatatct cttttggtat cctgtcatat aactttccgg tgattaattc cgctaaccgg
      301 tggtctgctg ctgaattaaa tgattcacgt tcactgttta ataaactgtc tctgttttta
      361 tgaataattt tttccagcgt attgactgat gaacatcgcc gtaactgata cagccattcc
      421 tgttttgttt tcgccatttt tattcccgct gagaacagat gaatgataag attgccatcg
      481 ctttatttac ggtgtctcca tatccagggg ggaaccggat cagcatctga ccagagccca
      541 cgtttttgtt gtctggcttc gttctgaagg acaggcagca cgggatctgt gttgtactgc
      601 tcatataccc aggcagcccc ggcccggacc ataaactgat taacattcat tccgtctggt
      661 gcataaacct gcccgagaat acgaccataa cgatctcgct gaaaatatgt gacggtaacc
      721 gtttttcctg caaccagtga tttcatcatg tccgttgacc accggccata atcctgtttc
      781 ttttccggtg catcaatatt tatcagcctg atccgcactg ccttccgtga gtccatgacc
      841 tcgatggtat caccgtccag tacacgaaca acccgtccat gaatatctgc acacaatacc
      901 ggccatgaaa agataaataa taccagtgga atatatttcc tcatgttatt ctccatatca
      961 gataaatggc acctgtattt caggtaatcc tgaatatcgc agcacacact gaataacacc
     1021 ttattttgtg aaattaatca caaaatataa aatcacgact taatacggaa aaaactctgt
     1081 gctactcaga actgtccggt catacttccc gaccggatat taaaaaaagc aaatctcatg
     1141 cattattcag ccttctgaat ccctggagta atgaaggctg ctttttcgtt acacccttcc
     1201 ccggcagcgc cggtggcagt gttcagccct ttttcgggca aactgctgcc agtctgtccg
     1261 gggagcagac tgcgcagccc gtagccatgc ctcagcggct cccggccagt cccccctgac
     1321 ttccagccgg acagcccggc gtccgacctg ccggtagcgc cataccccgg agttttgcga
     1381 atcacgccct gttccgttca ttttccttcc ccctttaatc caggccggtg aatgtgttat
     1441 aaatttttat aaccttcttc tgccgggtat ggaagaaggt ttcagagaag ccttattttt
     1501 ccgcctcctt tagtgtgaag gaggcttttt tattgttcat caagcacggc ctgaagttct
     1561 gcctttatcc ggttctggcg gcggatttta tccagacgct ctgccgcata cacttcttcc
     1621 tcctgagaaa tatgctccgt cacataccct tccgtgtcat accggcaggc accggctttc
     1681 atggcacaca gatagctttc tgaacgggtg atggccttca gcgccctgcg cagtttttta
     1741 tgcgagagcg ggatattccg ctgcgccacg tcttccagta acacgtcccg gataccgcag
     1801 gccagaagcc ggggtgtgtc accgtcaaat aatcccggcc accagggttt cagggtgttc
     1861 acggcttcat ccagtgtggg caggttcaga taaatggaca gcgcctgtct ggcctgcgct
     1921 ttttttgctg tcagctctgc ttcccgggca gccttctccg ccagtttctg ctttttcacc
     1981 ttccattttg gtggcgtggt gacattgatg atggttttcc ggctccgggt cggtgtttcc
     2041 ccttccgttt tccgtttcag tgtcagtacc ggtcgtttct gctctgtcat gattgccctg
     2101 acctttgtga aaatatgtcc tccaggtcgt tgaaactact cactatgata ttaagctgac
     2161 ctcaacgacc tctgacatat taataccgac aattaaagat gttttttaaa ccattgcgtc
     2221 tgtactgccg ccacacgttc aaaaaacgcg ccttcataaa tatcataatg gcatgcgtca
     2281 gcttcctcgt ataattcctt agtaccagaa gcaacagcat catataaggc ttttccctgt
     2341 tctggtggat taacactatc ctggccggca ataacaatca aaactgggca ctgtactttg
     2401 gctgcgctct ctgccggttt atattgcaac gtctccataa ccgtaaggaa aggtattttt
     2461 atatccattt caggatactg accttttacc ttctcgaaga atacctttga ttcattatca
     2521 ctcagtaccc gggtaacccc cacaaacatc tctttcccgg tgtttttctt cttctctgcc
     2581 attttattca gcgtggacag aaaagacgct ctctccgatt cattcatctc tccggtaacc
     2641 agaacatcac cgtcagcaaa agccagctgg ctgacaatac attttacgcg ttggtcctgc
     2701 gcagctgcac tgaagacatg cccccctccc agcgatgttc cccataaccc aatacgctga
     2761 ttatcaatac attcctgctt ttctgcccaa ttgataactg aaataatatc ttcggtctgc
     2821 attgcaggaa ccagacgccc tcgttctcca tcactctcac cgaatcctcg ataatcaaaa
     2881 gtaatcgttg cgaatcctgc ttctgtgaag gcattcgcaa agcaagggag cagaacattc
     2941 ctgataccgc aaaacccatg gcataagata atcaaaggat gttttatatt tccttcagga
     3001 acacgaaatg tcagggcaat accttcagag agtttgtgat ccgtaatttt cataaatatc
     3061 ctgtgttatg ttgtttatta ataatcagaa tcagcgtcag tatcatacca gtcacaacgc
     3121 cagaacgccc agcacagcca gatgacaggc gtagaatacc gggaaaaaat ccccgggcca
     3181 gaaacggggt aatgattttc ctgcacacga caccagacca acggtcagca ccgtcattac
     3241 aagaccggcc accgccgctg catcactgga ggcaaggtta agtgccggaa taacggccag
     3301 caggcatgca agcagcgcca gacgttccgc tctgtcttcc gcccggtaca gtcggtaact
     3361 gaccgccagc atcagcagcc cggcaatgcc gtaactggtg ccggacaaag gcccccacag
     3421 ggccatcaga agaatggccg ctgctgtacg ccacccactg cgcgtttcac accacgtcag
     3481 cacctgtgcc gccactgcaa aggcaaacag gatattcccc tcataccagg gaaagccggc
     3541 cagataatat gcgaactggg caataattcc ccatccccac agccggttaa tggccggttg
     3601 ccggatatgc gcatgacggg acagattcag cccccacacc agggcaaaca gcggaaaggc
     3661 tcctcgcccg gccagaaaca tccattcctg cttcagctgg aatatcagat tgatgtggtc
     3721 cagtaccatc agcaccagcg ccaccgtttt gatgatatcc cgctgtccgg gtgaccagac
     3781 cagaaacgac tgcaaccagg tatcggtccg tgcagccagt gaatcgttac gtgtcgtgtt
     3841 cgtgttatcc gttgtcatca gcgtttatct tcctgtatca gtctccgccc agggttttct
     3901 ctttctgcag gtcacgaacc atatcccgct ctatctgctg cagacgctcc tgcagcagat
     3961 tttcccgggc aacctcccgg accgcttcct gctcccgttg tgattcacgc agcacactct
     4021 ccggcagcgc ggcttcccgt tcagttatgt cagcccggtc acgctcctgc ccggcaattt
     4081 ccctgacagc ctgctctgtt ttgccatccg gcaggtcagg tttgttctct gccattttac
     4141 ggacaatttc atctgcacgg cgttccgttt cacggcggat ggcctcttca gcctgccgct
     4201 gtgccagcac ctctgccgtg accggttcgc catttccggc tcccggctgg acgctgctgt
     4261 ccgggatatc cccccacacg cgaccaccgg tgatggcacc gggattccac ggacgacctt
     4321 caccggcaat tcttaccacc acaccgctgt caggattatc acgggcaatc cggacaccat
     4381 cctgcatatt atcagccagc aggctctctc cgttacggct accctgcagg gccacgaact
     4441 gcgcatcccc gctgcctttc acccgtcctt caccgctgaa tccccgcagc ccgtttccgt
     4501 catccgtggt cagtgggttc agccagatac cggcggactt gccgttacgg tcaaacgccg
     4561 gcagtgccac atacggctgc ggatatttac gtcccggtgc aataaaccgt gcagggctgt
     4621 ctcccccggc cagccc
//
LOCUS       DAPOAV010000185         4563 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.188, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000185 DAPOAV010000000
VERSION     DAPOAV010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4563
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.188"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..338)
                     /locus_tag="RN951_004399"
     CDS             complement(<1..338)
                     /locus_tag="RN951_004399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529282.1"
                     /translation="MSGKPAARQGDMTQYGGSIVQGSAGVRIGAPTGVACSVCPGGVT
                     SGHPVNPLLGAKVLPGETDIALPGPLPFILSRTYSSYRTKTPAPVGSLGPGWKMPADI
                     RLQLRDNTLIL"
     gene            566..1174
                     /locus_tag="RN951_004400"
     CDS             566..1174
                     /locus_tag="RN951_004400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase"
                     /protein_id="HDX2529283.1"
                     /translation="MKLVGSYTSPFVRKLSILLLEKGITFEFINELPYNADNGVAQFN
                     PLGKVPVLVTEEGECWFDSPIIAEYIELMNVAPAMLPRDPLESLRVRKIEALADGIMD
                     AGLVSVREQARPAAQQSEDELLRQREKINRSLDVLEGYLVDGTLKTDTVNLATIAIAC
                     AVGYLNFRRVAPGWCVDRPHLVKLVENLFSRESFARTEPPKA"
     gene            1272..2663
                     /gene="selA"
                     /locus_tag="RN951_004401"
     CDS             1272..2663
                     /gene="selA"
                     /locus_tag="RN951_004401"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HDX2529284.1"
                     /translation="MTTETRSLYSQLPAIDRLLRDSSFLSLRDTYGHTRVVELLRQML
                     DEAREVIRGSQTLPAWCENWAQEVDARLTKEAQSALRPVINLTGTVLHTNLGRALQAE
                     AAVEAVAQAMRSPVTLEYDLDDAGRGHRDRALAQLLCRITGAEDACIVNNNAAAVLLM
                     LAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNEN
                     TALLMKVHTSNYSIQGFTKAIDEAELVALGKELDVPVVTDLGSGSLVDLSQYGLPKEP
                     MPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLKRALRADKMTLAAL
                     EATLRLYLHPEALSEKLPTLRLLTRSAEVIQIQAQRLQAPLAAHYGAEFAVQVMPCLS
                     QIGSGSLPVDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRC
                     LEDEQRFLEMLLK"
     gene            2660..4504
                     /gene="selB"
                     /locus_tag="RN951_004402"
     CDS             2660..4504
                     /gene="selB"
                     /locus_tag="RN951_004402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HDX2529285.1"
                     /translation="MIIATAGHVDHGKTTLLQAITGVNADRLPEEKKRGMTIDLGYAY
                     WPQPDGRVPGFIDVPGHEKFLSNMLAGVGGIDHALLVVACDDGVMAQTREHLAILQLT
                     GNPMLTVALTKADRVDEARVDEVERQVKEVLREYGFAEAKLFITAATEGRGMDALREH
                     LLQLPEREHASQHSFRLAIDRAFTVKGAGLVVTGTALSGEVKVGDSLWLTGVNKPMRV
                     RALHAQNQPTETANAGQRIALNIAGDAEKEQINRGDWLLADVPPEPFTRVIVELQTHT
                     PLTQWQPLHIHHAASHVTGRVSLLEDNLAELVFDTPLWLADNDRLVLRDISARNTLAG
                     ARVVMLNPPRRGKRKPEYLQWLASLARAQSDADALSVHLERGAVNLADFAWARQLNGE
                     GMRELLQQPGYIQAGYSLLNAPVAARWQRKILDTLATYHEQHRDEPGPGRERLRRMAL
                     PMEDEALVLLLIEKMRESGDIHSHHGWLHLPDHKAGFSEEQQAIWQKAEPLFGDEPWW
                     VRDLAKETGTDEQAMRLTLRQAAQQGIITAIVKDRYYRNDRIVEFANMIRDLDQECGS
                     TCAADFRDRLGVGRKLAIQILEYFDRIGFTRRRGNDHLLRDALLFPEK"
BASE COUNT         1034 a         1164 c         1337 g         1028 t
ORIGIN      
        1 agtatcagtg tgttatcgcg cagctgtaag cggatatccg caggcatttt ccagccgggg
       61 ccgaggctcc ccaccggcgc gggcgttttt gtccggtaac tgctgtaggt gcgggagagg
      121 atgaacggca gcgggccggg cagggcgatg tcggtttcac cgggaaggac ctttgcaccg
      181 agcaggggat tgaccggatg gccggacgtc actccgccgg ggcacaccga acaggccacg
      241 ccggtggggg caccaatgcg caccccggct gaaccctgaa caatgctacc gccatactgc
      301 gtcatgtcgc cctgacgcgc tgccggtttt ccgctcattt ctcatccttg ttttatcggg
      361 ttatttgtct gctgacaggc gaaaccctac agatttataa gaaagcctga agtgagatat
      421 ccatcagagt gaaataatta ggaaaatatt tatatcacca tgataaatat gtgatttatt
      481 tggaagtaac aaaccatcaa cattttctgc cctttttccc atcaccaggc catactgata
      541 tttttcctcg cacaaaggac tcggcatgaa actcgtcggt agctacacca gcccgtttgt
      601 acgcaaactt tctattctgt tgttagaaaa gggcataact ttcgaattta ttaatgaact
      661 gccctataac gcggacaacg gcgtggcgca atttaacccg ttaggaaaag tgccggtgct
      721 ggtgaccgaa gagggcgaat gctggtttga ttcgccgatc atcgctgaat atattgaatt
      781 aatgaatgtc gctccggcga tgttgccgcg cgatccgctg gagtcgttgc gggtgcgcaa
      841 aattgaggca ctggcggatg gcattatgga tgccgggctg gtatcggtgc gtgaacaggc
      901 gcgtccagcg gcgcagcagt ctgaagatga attgttacgc cagcgggaga aaatcaaccg
      961 cagtctggat gtgctggaag gatatctggt cgatggcaca ctcaaaaccg atacggtcaa
     1021 tctggcgact atcgccattg cctgtgccgt cggatatctc aatttccgcc gcgttgcgcc
     1081 aggttggtgt gtcgaccgcc cacacttagt caaactggtc gaaaacctgt ttagccgcga
     1141 aagttttgct cgcaccgaac cgccaaaggc ttgatgcgcg atatgtcctc ctgacccatc
     1201 tcacgttaca atccgtggtt atgttaaacg cccttctccg tgtgagaggg ccttgatcag
     1261 ccaggtttcc tatgacaacc gaaacgcgtt ccctctatag tcaacttccg gctattgatc
     1321 gcttattgcg cgatagctcc ttcctttctt tgcgtgatac ttatggtcac acccgcgtgg
     1381 tggaattgtt gcgtcagatg ctcgacgaag cgcgagaagt gattcgtggc agccagacgc
     1441 tgcctgcgtg gtgtgaaaac tgggcgcaag aagtcgatgc ccggttgacg aaagaagcgc
     1501 agagcgcgct gcgtccggtg atcaacctga cgggaaccgt gctgcatacc aaccttgggc
     1561 gagctttaca ggcggaagcc gcggtggaag ccgttgcgca ggctatgcgt tcgccagtga
     1621 ccctcgagta tgatctggac gacgccggac gcggacatcg cgatcgggcg ctggcgcagc
     1681 tgctgtgccg tattacgggg gcggaagatg cctgtatcgt caataacaat gcggcggcgg
     1741 tgttattgat gttggcggcc actgccagcg gaaaagaggt ggtggtatct cgcggcgaac
     1801 tggtggagat tggcggcgcg tttcgtattc ccgatgttat gcgtcaggca ggctgcaccc
     1861 tacacgaagt agggaccacc aaccgcacgc acgcgaatga ttatcgtcag gcggtgaatg
     1921 aaaataccgc actgttgatg aaagtacata ccagtaacta cagcattcag gggttcacca
     1981 aagcgataga tgaagcggaa ctggtggcgc tcggcaaaga gctggatgtt cccgtagtga
     2041 ctgatttagg cagtggctcg ctggtcgatc ttagccagta cggtttgccg aaagagccaa
     2101 tgccgcagga gttgattgcg gcgggcgtca gtctggtgag tttctccggc gacaagttgt
     2161 taggcgggcc gcaggcagga attattgttg gtaaaaaaga gatgatcgcc cgcctgcaaa
     2221 gccacccgct gaagcgtgca ttacgcgcgg ataaaatgac cctcgcggcg ctggaagcca
     2281 cgttgcgtct ttatttacac cctgaagctc tgagtgaaaa attaccgacc ctgcgcctgc
     2341 ttacccgcag cgcagaggtc attcaaatcc aggcacaacg tttacaggcc ccccttgccg
     2401 cacattacgg cgcggagttt gcggtacagg ttatgccatg tctttcgcag attggcagtg
     2461 gttcgctgcc ggttgatcgc ctgccgagcg cggcattaac gtttacaccc catgatggac
     2521 gcggtagcca ccttgagtca ttagccgccc gctggcgtga attgccagtg ccggtgattg
     2581 gtcgtattta tgacggacga ttgtggctgg atttacgctg ccttgaagat gagcaacggt
     2641 ttttggagat gttgttgaaa tgattattgc gactgccgga cacgttgacc acggcaaaac
     2701 aaccttattg caggcgatta ctggcgtaaa tgctgaccgt ctgccggaag aaaaaaagcg
     2761 cggcatgacc atcgatctcg gctatgccta ctggccgcag ccggatggtc gcgtgcctgg
     2821 ttttatcgac gttcccggtc atgaaaagtt tctttccaac atgctggcgg gcgttggtgg
     2881 tatcgatcac gcgctgttgg tggtggcgtg cgatgacggc gtgatggcac agacccgtga
     2941 gcatctggcg attttgcagc tgaccggtaa cccgatgctg acagtggcgc tgaccaaagc
     3001 cgatcgcgtg gacgaagcgc gtgttgatga ggttgaacgc caggtaaagg aggttctgcg
     3061 ggaatacggt tttgctgagg caaaactgtt tatcaccgca gcaaccgaag gtcggggaat
     3121 ggatgccctg cgcgagcatc tgcttcagtt gccggaacgc gagcacgcca gccaacatag
     3181 tttccgcctc gcgattgacc gcgcatttac cgtaaaaggt gccgggctgg tcgtcaccgg
     3241 tacggcgtta agcggggaag tgaaggtagg cgattcactc tggctgactg gtgtaaataa
     3301 accgatgcgt gtacgtgcgc tgcatgcgca aaaccagcca acagaaaccg ccaatgccgg
     3361 gcagcgtatc gcgcttaaca tcgcgggtga tgcggaaaaa gagcagatta accgtggcga
     3421 ctggctgctt gccgatgtgc cgccagagcc gttcacacgg gtgattgtcg agcttcaaac
     3481 ccatacaccg ctgacccagt ggcagccgct gcatattcac cacgccgcca gccacgtcac
     3541 gggacgcgtt tcactgctgg aagataacct tgctgaactg gtcttcgaca ccccgttatg
     3601 gctggcagat aacgaccgcc tggtattgcg cgatatctct gcccgcaaca cgctggccgg
     3661 agcgcgcgtc gtgatgctta acccgccgcg tcgcggtaaa cgtaagccgg aatatctgca
     3721 atggctggcg tctcttgcac gggcgcagag cgatgccgat gcgttatctg ttcatctgga
     3781 acgcggcgcg gttaaccttg cggatttcgc ctgggcgcgc cagctcaacg gcgaagggat
     3841 gcgcgaattg ctgcaacagc ctggttatat tcaggctggt tatagcttgt tgaatgcgcc
     3901 ggttgccgcc cgctggcagc ggaaaattct cgacacatta gcgacttatc atgagcaaca
     3961 tcgcgatgaa cctggccctg ggcgcgaacg tctgcgacgt atggcgttgc caatggaaga
     4021 tgaagcgctg gtactgttgc tgattgaaaa gatgcgcgaa agcggcgaca tccacagcca
     4081 tcacggctgg ctgcatctgc cagatcacaa agcgggcttc agcgaagagc agcaggccat
     4141 ctggcaaaaa gcagagccac tgtttggtga cgaaccgtgg tgggtgcgtg acctggcaaa
     4201 agagacggga accgacgagc aggcaatgcg cctgactcta cgccaggcgg cgcagcaagg
     4261 aataattacc gcgatcgtta aagatcgtta ttaccgtaac gatcggattg tcgagtttgc
     4321 caatatgatc cgcgatctcg atcaggagtg tggttcaacc tgcgcggcgg atttccgcga
     4381 tcgcttaggc gtaggccgaa agctggcaat tcagattctg gaatattttg accgcattgg
     4441 ctttacgcgt cgtcgtggaa atgatcattt attgcgcgac gcattattat ttccggaaaa
     4501 ataaggaaat gattaattaa gttttaaaat aaattaatac aaaattctta tgaatttaaa
     4561 aaa
//
LOCUS       DAPOAV010000186         4554 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.189, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000186 DAPOAV010000000
VERSION     DAPOAV010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4554
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.189"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..1242)
                     /locus_tag="RN951_004403"
     CDS             complement(<1..1242)
                     /locus_tag="RN951_004403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006120210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HDX2529286.1"
                     /translation="MAINVLSPKQIENAKPKTNDYKLTDGGSLYLLVRKTGGKYWRMN
                     YRFDGKQVTLALGVYPDVSLATARKRRDEARQLLADGRDPREAKKPKKEDPISPTFES
                     VAREWHSRTIGHPEWKEITRKKILREMENHLFPAIGSKPIDTLKTRDLMPMLVEMTEK
                     GIGATTSRVKTTMTSIFRYAVQRGIVDYNPAHDLKGAITTPKVRHRPALPLERLPELL
                     AKTRSYTGRPLTRLAVLFSLHTFVRSSELRHARWEEIDIENGLWTIPGQREEIAGVKF
                     SERGAKMGAAHYVPLSSQAIGVLEDIRKISGEYLLVFPGDSNPYKPMSENTVNKALRT
                     MGYDTQSDVCLHGFRAMACSALTESGLWSRDAVERQMSHQERNEVRAAYVHLAQHMQE
                     RRRMMQWWSNYLELNKDEFHAP"
     gene            complement(1430..1501)
                     /locus_tag="RN951_004404"
     tRNA            complement(1430..1501)
                     /locus_tag="RN951_004404"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1466..1468),aa:Arg,seq:cct)
     gene            complement(1577..2509)
                     /locus_tag="RN951_004405"
     CDS             complement(1577..2509)
                     /locus_tag="RN951_004405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDX2529287.1"
                     /translation="MDNDKIDQHSDEIEVESEEKERGKKIEIDEDRLPSRAMAIHEHI
                     RQDGEKELERDAMALLWSAIAAGLSMGASLLAKGIFHVELEGVPGSFLLENLGYTFGF
                     IIVIMARQQLFTENTVTAVLPVMQKPTMSNVGLLMRLWGVVLLGNILGTGIAAWAFEY
                     MPIFNEETRDAFVKIGMDVMKNTPSEMFANAIISGWLIATMVWMFPAAGAAKIVVIIL
                     MTWLIALGDTTHIVVGSVEILYLVFNGTLHWSDFIWPFALPTLAGNICGGTFIFALMS
                     HAQIRNDMSNKRKAEARQKAERAENIKKNDKNPA"
     gene            2804..3559
                     /gene="mlaA"
                     /locus_tag="RN951_004406"
     CDS             2804..3559
                     /gene="mlaA"
                     /locus_tag="RN951_004406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding lipoprotein MlaA"
                     /protein_id="HDX2529288.1"
                     /translation="MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNF
                     NVLDPYIVRPVAVAWRDYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTR
                     FFLNTILGMGGFIDVAGMANPKLQRTEPHRFGSTLGHYGAGYGPYVQLPFYGSFTLRD
                     DGGDMADGLYPVLSWLTWPMSVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYF
                     QRHDFIANGGELKPQENPNAQAIQDDLKDIDSE"
     gene            complement(3741..4415)
                     /locus_tag="RN951_004407"
     CDS             complement(3741..4415)
                     /locus_tag="RN951_004407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529289.1"
                     /translation="MIFSALKEIYDGDPSFIFDKISHKLRHTVTEFDESGNSEPTDLF
                     TWYGKDKKGDSLAIVIKNKNGNDYLSLGYYDQDDYHIQRGIRINGDSLTQYCSEKARN
                     ASAWFESSKAIMAESFATGSDHQVVNELNGERLREPNEVFKRLGRAIRYNFQVDDAKF
                     RRDNVKEIISTLFANKVDVDHPENKYKDFKDLEDKVEKRLQNRQTEYQNEINQLSAPG
                     VNFDDI"
BASE COUNT         1108 a         1052 c         1024 g         1370 t
ORIGIN      
        1 aggagcatga aattcgtcct tatttagttc cagataatta gaccaccatt gcatcattct
       61 gcggcgttcc tgcatgtgct gcgcaagatg cacatatgct gcccgcactt cgtttctttc
      121 ttggtgactc atctgccgtt caactgcatc gcgtgaccag agtcctgatt cggtcagtgc
      181 agagcaggcc atcgccctga acccatgcaa gcaaacatca ctttgagtgt cgtaacccat
      241 cgttcgcagt gctttattaa ctgtgttttc gctcatcggt ttatatgggt tgctgtcacc
      301 ggggaaaacc agcagatatt caccactgat tttccttata tcctccagta ccccgatagc
      361 ctgactagat agcgggacat aatgagcagc ccccatcttt gcaccccgct ctgagaattt
      421 aacccctgcg atctcttcac gttgtcctgg tatcgtccat agcccatttt caatgtcgat
      481 ctcctcccat ctggcatgtc gtagttcgct ggatcgcaca aaagtgtgca gggaaaatag
      541 aactgctagg cgagtcaatg gtcttcccgt gtaacttctc gttttcgcta acagttcagg
      601 taaacgttcg agaggtagtg cggggcgatg tcgtactttg ggggtcgtaa ttgcaccttt
      661 tagatcgtgg gcagggttgt aatcgacaat tccacgttgc acggcataac ggaagatgct
      721 cgtcatagtg gtttttaccc ggctcgttgt ggcaccaatt cctttctcag tcatctcaac
      781 cagcatcggc atcaagtcac gggttttgag cgtatcgata ggctttgaac cgatggcagg
      841 aaagaggtgg ttttccattt ctcggagaat ttttttacgg gtgatctctt tccactcagg
      901 atgccctatc gttctactat gccactctct ggcaacactc tcgaacgtgg gggaaattgg
      961 gtcttccttt ttgggtttct ttgcttcgcg aggatcacga ccatcggcta gtagttgcct
     1021 ggcttcatca cgccgtttcc gcgctgttgc aagtgagaca tctgggtaga cccctaatgc
     1081 caatgtcact tgttttccat caaaacgata attcatacgc cagtattttc caccagtctt
     1141 tcgtaccagt agatacaaac tccctccatc ggtaagtttg taatcattgg tcttcggctt
     1201 ggcgttttct atctgtttgg gggaaagcac attaatggcc atatctgtac tcattttggt
     1261 agattgatgg tatctgcata tcgaactggg gaataccatc acttatacca tcacgaggtt
     1321 gtaatgtcat gaaattaact gaaatgaaaa tcaggccgat tcggtgataa cttactgttt
     1381 ttttaagtgg ttatgtaatg aagtgaaatg tagagaaagg tctttaaagt gtcccctgca
     1441 ggaatcgaac ctgcaattag cccttaggag gggctcgtta tatccattta actaagagga
     1501 caatgcggca tgagtatacc cgctaatgga ctgcggggta agtacgctgc cgctcgattg
     1561 cttaaaccct cgccatttat gctgggtttt tatcattttt cttaatgttt tccgcacgtt
     1621 ctgctttttg gcgtgcttct gctttacgct tgttgctcat gtcgttacga atctgtgcat
     1681 gactcattaa cgcgaagata aaggtgccgc cgcagatgtt ccccgctaaa gtaggtagtg
     1741 cgaagggcca gatgaaatcg ctccagtgca gcgtgccgtt aaacaccaga tagaggattt
     1801 caacagaacc gacaacgatg tgggtggtgt cacccagtgc aataagccag gtcatcaata
     1861 taatcaccac aatctttgcc gcacccgcag caggaaacat ccaaaccata gtggcgatca
     1921 gccagccgga aatgatcgcg ttggcaaaca tctcgctggg ggtgttcttc atcacatcca
     1981 tgccgatttt gacaaatgca tcgcgagttt cttcattgaa gataggcata tattcaaatg
     2041 cccatgcagc aatacctgtc ccgagaatat tacccagcag cacgacgccc cataatcgca
     2101 taagtaagcc gacgttgctc attgtcggtt tttgcatgac gggtagtacc gcagtcacgg
     2161 tgttttcggt aaataattgc tggcgggcca taatgacgat aataaaacca aaggtataac
     2221 cgagattctc cagtaagaag ctgcctggca ctccttccag ttcgacatga aatatccctt
     2281 ttgccagtag cgaagcgccc atcgacagac ccgccgcaat ggctgaccac agtagcgcca
     2341 ttgcgtcgcg ttccagctct ttttcaccat cctggcggat atgctcatga attgccatcg
     2401 cccgggaggg gagtcggtct tcatctattt ctattttttt gccgcgctct ttttcttcgc
     2461 tctcaacttc aatttcgtcg ctgtgttgat caattttgtc gttgtccatg gtctcttctc
     2521 ttgaattagc acgtatagct aaagcgtagc ggcttttttg ctcgcaactg gcgggagtta
     2581 ctctgaaaat gtagaaaagg ctgcgtttgc ctttttctgt ttctatagaa tcaagtagcc
     2641 tacagggcgg cgattaccag gctatgatca aatcagcaaa tcagggcgtc tggacatcag
     2701 ttgacgtgct gttacaatcg cccacaccta aacaggcgga tacggtatcg ttccgtcatg
     2761 gatggcaaac tgcataagcc ataaaaaaaa cagggagaca tttatgaagc ttcgcctgtc
     2821 ggcgcttgct ctgggaacta cgcttctggt ggggtgtgcg agttccggta cagatcagca
     2881 agggcgttct gacccgttag aagggttcaa ccgcaccatg tacaacttca acttcaacgt
     2941 attagacccg tatattgttc gaccggtcgc tgtcgcctgg cgtgattatg ttccgcaacc
     3001 ggcgcgtaat ggtttgagca actttactgg caaccttgaa gaacctgcgg tgatggttaa
     3061 ctacttcttg cagggcgacc cttatcaggg gatggtccac tttacccgct ttttcctgaa
     3121 caccattttg gggatgggcg gttttattga tgttgcaggg atggcgaacc cgaaactgca
     3181 acggactgaa cctcaccgct tcggtagtac gcttggtcat tatggcgcgg gttatgggcc
     3241 ttacgtccag ttaccgttct acggtagctt cacgctgcgt gatgacggtg gtgatatggc
     3301 ggatggtctt tacccggttc tttcctggct gacctggccg atgtctgtgg gtaaatggac
     3361 gcttgaaggg atagaaactc gtgcgcagtt gttggattcc gatggtctgc tgcgtcagtc
     3421 gtccgatcct tatattatgg tgcgcgaagc gtacttccag cgtcatgatt tcatcgctaa
     3481 tggcggcgaa ctcaaaccgc aggaaaatcc gaacgcgcaa gcgattcagg atgatttaaa
     3541 agatatcgat tctgaataag aaacaaataa aaaaggtgag tcgcaatact cacctttttt
     3601 gttgttatcc ctcaattacc acaagtaaaa ggagataaac cgacaatgac ccggacgtaa
     3661 tgatgtaaaa atactgatgt tcgtcactga ctatttccga tattcaggag ttgaaaaatc
     3721 aaaaaactgg aaaaataatt ttaaatatca tcaaaattaa cacctggcgc agatagttga
     3781 ttaatttcat tttgatattc cgtctggcga ttttgaagcc ttttttcaac tttatcttcg
     3841 agatccttaa agtctttgta tttattttca ggatggtcaa cgtcaacttt gttagcgaat
     3901 aaagtagaaa ttatttcttt tacattatcg cgtctaaatt ttgcatcgtc cacttgaaaa
     3961 ttatatctta ttgctcgacc taaacgttta aaaacttcgt taggttctct cagtctttcc
     4021 ccgttgagct cgtttacaac ctgatgatcg gaacctgttg caaatgattc tgccatgata
     4081 gctttactgc tttcaaacca cgctgaagca ttcctggctt tttcactaca atattgggtg
     4141 agactatcac cattaatacg aattcctctt tgaatgtggt agtcgtcctg atcgtagtaa
     4201 ccgagagata agtaatcatt tccgttttta tttttaatta caatagcgag agagtcgcct
     4261 tttttatctt taccgtacca ggtaaataag tccgttggtt cgctattccc gctctcatca
     4321 aattccgtta ccgtatgtct gagtttgtgt gatatcttat cgaagataaa actaggatct
     4381 ccatcatata tttcttttaa tgcgctgaag atcatttcct tattattgat atcatgagtc
     4441 ttctcaacta tgttgtcatt aatgatagta cggacgagtt ctttgtcttt atagttcgca
     4501 ggtaattcta ttggttcttg gttgtcgata ccaatattaa tatggtctgt atca
//
LOCUS       DAPOAV010000187         4473 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.191, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000187 DAPOAV010000000
VERSION     DAPOAV010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4473
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.191"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            219..2369
                     /gene="btsT"
                     /locus_tag="RN951_004408"
     CDS             219..2369
                     /gene="btsT"
                     /locus_tag="RN951_004408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418774.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate/proton symporter BtsT"
                     /protein_id="HDX2529290.1"
                     /translation="MDTKKIFKHIPWVILGIIGAFCLAVVALRRGEHVSALWIVVASV
                     SVYLVAYRYYSLYIAQKVMKLDPTRATPAVINNDGLNYVPTNRYVLFGHHFAAIAGAG
                     PLVGPVLAAQMGYLPGTLWLLAGVVLAGAVQDFMVLFISSRRNGASLGEMIKEEMGPV
                     PGTIALFGCFLIMIIILAVLALIVVKALAESPWGVFTVCSTVPIALFMGIYMRFIRPG
                     RVGEVSVIGIVLLVASIYFGGVIAHDPYWGPALTFKDTTITFALIGYAFVSALLPVWL
                     ILAPRDYLATFLKIGVIVGLALGIVVLNPELKMPAMTQYIDGTGPLWKGALFPFLFIT
                     IACGAVSGFHALISSGTTPKLLANETDARFIGYGAMLMESFVAIMALVAASIIEPGLY
                     FAMNTPPAGLGITMPNLHEMGGENAPIIMAQLKDVTAHAAATVSSWGFVISPEQILQT
                     AKDIGEPSVLNRAGGAPTLAVGIAHVFHKVLPMADMGFWYHFGILFEALFILTALDAG
                     TRSGRFMLQDLLGNFIPFLKKTDSLVAGIIGTAGCVGLWGYLLYQGVVDPLGGVKSLW
                     PLFGISNQMLAAVALVLGTVVLIKMKRTQYIWVTVVPAVWLLICTTWALGLKLFSTNP
                     QMEGFFYMASQYKEKIANGTDLTAQQIANMNHIVVNNYTNAGLSILFLIVVYSIIFYG
                     FKTWLAVRNSDKRTDKETPYVPIPEGGVKISSHH"
     gene            2419..2622
                     /locus_tag="RN951_004409"
     CDS             2419..2622
                     /locus_tag="RN951_004409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HDX2529291.1"
                     /translation="MFGNLGQAKKYLGQAAKMLIGIPDYDNYVEHMKTNHPDKPYMSY
                     EEFFRERQNARYGGDGKGGMRCC"
     gene            2633..3589
                     /gene="yjiA"
                     /locus_tag="RN951_004410"
     CDS             2633..3589
                     /gene="yjiA"
                     /locus_tag="RN951_004410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313338.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase"
                     /protein_id="HDX2529292.1"
                     /translation="MNPIAVTLLTGFLGAGKTTLLRHILNEQHGYKIAVIENEFGEVS
                     VDDQLIGDRATQIKTLTNGCICCSRSNELEDALLDLLDNLDKGNIQFDRLVIECTGMA
                     DPGPIIQTFFSHEILCQRYLLDGVIALVDAVHADEQMNQFTIAQSQVGYADRILLTKT
                     DVAGEAEKLRERLARINARAPVYTVTHGDIDLGLLFNTNGFMLEENVVSTKPRFHFIA
                     DKQNDISSIVVELDYPVDISEVSRVMENLLLESADKLLRYKGMLWIDGEPNRLLFQGV
                     QRLYSADWDRPWGDEKPHSTMVFIGIQLPEEEIRAAFAGLRK"
     gene            complement(3623..3925)
                     /locus_tag="RN951_004411"
     CDS             complement(3623..3925)
                     /locus_tag="RN951_004411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004020443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnA antitoxin family protein"
                     /protein_id="HDX2529293.1"
                     /translation="MSMVKHKRGTSSTLDVQHEAELKALANKSDEDIDYSDIPPSSDE
                     QWSNAERGKFYRPLKTQASVRIDADVMEWLKRPGKGYQTRLNAILREAMLRDQNKK"
     gene            complement(3912..4199)
                     /locus_tag="RN951_004412"
     CDS             complement(3912..4199)
                     /locus_tag="RN951_004412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnT family toxin"
                     /protein_id="HDX2529294.1"
                     /translation="MPMEFEWDENKAKSNRVKHGIRFEDAVLLFDDPQHLSQQERIEN
                     GEYRWQTIGLVYGIVVILVAHTIRFESGNEIIRIISARKADRKERNRYEHG"
     gene            complement(4398..>4473)
                     /locus_tag="RN951_004413"
     CDS             complement(4398..>4473)
                     /locus_tag="RN951_004413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="HDX2529295.1"
                     /translation="LSFSKSVELHDKVIGHYLNIKHYQ"
BASE COUNT          990 a         1201 c         1147 g         1135 t
ORIGIN      
        1 atcacatatt tatcgtcact taaacgacgc ctttgccgct caaccgcaaa actgaccgct
       61 tacatcccta aaataaccac tcagttattt accttacttt acgcgcgcgt aactctggca
      121 acatcactac aggatagcgg tcaatttacc tcctcaaacg caacgcaaac ctagaacggc
      181 ttcggccaac tattaatcaa tacatgccag gttttactat ggatactaaa aagatattca
      241 agcacatacc ctgggtgatt ctcggaatca tcggtgcatt ctgcctcgcg gtagttgcat
      301 tacgtcgggg ggagcacgtc agcgccctgt ggatcgtggt cgcctctgta tcggtgtatc
      361 tggtggcgta tcgctactac agtctgtaca tcgcccagaa ggtgatgaaa ctcgacccca
      421 cgcgcgcgac gcctgcggtt attaacaacg acggtctgaa ctacgttccg accaaccgtt
      481 acgtgttgtt tggtcaccat ttcgccgcta tcgccggtgc tggtccgctg gtgggtccgg
      541 ttctcgccgc gcagatgggc tacctgcctg gcacgctgtg gctgctggcg ggggtcgtgc
      601 tggccggtgc ggttcaggac tttatggtgc tgtttatctc ctctcgccgt aatggcgcat
      661 ctcttggtga gatgatcaaa gaagagatgg gaccagtacc ggggactatc gcgctgtttg
      721 gctgtttctt aatcatgatc atcatcctcg ccgtcctggc gctgattgtg gttaaagccc
      781 tggccgaaag tccgtggggt gtcttcaccg tttgctcaac cgtaccgatt gcgctgttta
      841 tgggtatcta catgcgcttt attcgtccgg ggcgtgtggg tgaagtctct gtcattggta
      901 tcgtgctgct ggttgcctct atctacttcg gtggcgtgat tgctcacgat ccgtactggg
      961 gtccggcact gacctttaaa gacaccacca ttaccttcgc gctgattggc tatgcgtttg
     1021 tttccgcact gctgccggtg tggctgatcc tcgcaccgcg cgactatctg gcaaccttcc
     1081 tgaaaatcgg cgttatcgtc ggcctggcgc tgggtatcgt ggtgctgaac ccggaactga
     1141 aaatgcctgc catgacccag tacattgacg gtactggccc gctgtggaaa ggcgctctgt
     1201 tcccgttcct gttcatcacc atcgcctgtg gtgcggtatc tggcttccac gcgctgatct
     1261 cttccggtac gacgccaaaa cttctggcta atgaaaccga cgcgcgtttc atcggctacg
     1321 gcgcaatgct gatggagtcc ttcgtggcga ttatggcgct ggttgctgcg tccatcatcg
     1381 aaccgggtct ttacttcgcg atgaacaccc cgcctgctgg ccttggcatc accatgccta
     1441 acctgcatga aatgggtggc gagaacgcgc cgatcatcat ggcgcagctg aaagacgtta
     1501 ccgcacacgc ggcagcgacc gtcagctcct ggggcttcgt gatttcgcca gagcagatcc
     1561 tgcaaaccgc gaaagacatt ggtgagcctt ctgtcctgaa ccgtgcaggt ggtgcgccga
     1621 cgctggcggt aggtatcgct cacgtgttcc acaaagtgct gccgatggct gacatgggct
     1681 tctggtatca cttcggtatt ctgttcgaag cactgttcat cctgaccgcg ctggatgcgg
     1741 gtacccgttc tggccgcttt atgctgcaag acctgctggg taacttcatc ccgttcctga
     1801 aaaaaaccga ctctctggtt gccggtatca tcggtactgc gggctgtgtg ggtctgtggg
     1861 gctacctgct gtatcagggc gtggtcgatc cgctgggcgg cgttaagagc ctgtggccgc
     1921 tgttcggtat ttccaaccag atgctggcag ccgtagcgct ggtactgggc accgttgtgc
     1981 tgattaagat gaagcgcacc caatacatct gggtaactgt tgttccggct gtatggctgc
     2041 ttatctgcac cacctgggcg ctgggcctga aactgttcag caccaacccg cagatggaag
     2101 gcttcttcta catggcaagc cagtacaaag agaagattgc taacggtact gacctgacgg
     2161 cgcagcagat tgccaacatg aaccacatcg ttgtgaacaa ctacaccaac gcaggtctga
     2221 gtattctgtt cctgattgtg gtgtacagca tcatcttcta cggtttcaaa acctggcttg
     2281 cggtgcgtaa cagcgacaaa cgtactgaca aagaaacacc gtacgttcca atcccggaag
     2341 gcggcgtgaa gatctcttcg caccactaac cgtgtttagc cccgcttcgg cggggctttg
     2401 ttcttatcag agtgaactat gtttggtaac ttaggacagg caaaaaaata tctcggccag
     2461 gcggcgaaga tgttgattgg cattccagac tacgacaact acgtcgagca tatgaagacc
     2521 aaccatcccg acaagccgta catgagctat gaagaattct tccgcgaacg ccagaacgca
     2581 cgctacggcg gcgatggtaa aggcggtatg cgctgttgtt aatggagaga gcatgaaccc
     2641 gattgcagtt accctactca ccggtttttt aggcgcgggc aaaaccaccc tgctgcgcca
     2701 tattcttaac gaacaacacg gctacaagat tgccgtgatt gaaaacgaat tcggcgaagt
     2761 ctccgttgat gatcaactga ttggcgaccg cgccacgcag atcaaaacgc tgaccaacgg
     2821 ctgcatctgc tgttcgcgct ccaacgagct ggaagacgca ctactcgacc tgctggataa
     2881 tctcgacaag ggcaatattc agttcgaccg tctggtcatt gaatgcaccg gcatggccga
     2941 tcccggcccg attattcaga cctttttctc ccatgagatt ttatgccagc gctacctgct
     3001 ggacggcgtg attgcgctgg tggatgcggt acatgccgat gagcagatga accagttcac
     3061 catcgcccag tcccaggttg gctacgccga ccgtattctg ctgacgaaaa ccgacgtcgc
     3121 aggcgaagca gagaaactgc gtgaacgcct ggcgcgcatc aacgcccgcg caccggtcta
     3181 caccgttacc cacggcgata tcgacctggg ccttctgttc aacaccaacg gttttatgct
     3241 ggaagaaaac gtcgtcagca ccaaaccgcg tttccacttt atcgcggaca aacaaaacga
     3301 tatttcgtcg attgtggtgg aactggatta cccggtagat atcagcgaag tttcccgggt
     3361 gatggaaaac ctgctgctgg agtcggcgga taaactactg cgttacaaag ggatgctatg
     3421 gattgacggc gaacctaacc gcctgctatt ccagggcgtc caacgcctct acagcgccga
     3481 ctgggaccgc ccgtggggcg atgaaaaacc gcatagcacg atggtgttta tcgggattca
     3541 gttgccggag gaagagattc gggcagcgtt tgcggggttg aggaagtaat tttggatgat
     3601 ggccgccatg tggcggcctg aattattttt tgttctgatc gcgcagcatc gcttcacgta
     3661 aaattgcgtt caggcgagtt tgatagcctt tacctggtcg cttcaaccat tccatcacat
     3721 cagcatcaat acgcaccgaa gcctgagttt tcaatggccg ataaaactta ccgcgttcgg
     3781 cgttagacca ttgctcatcg ctggaaggtg ggatatcact gtaatcaata tcttcgtcgg
     3841 atttattcgc cagcgccttc agttcggcct catgctgcac atcgagtgta gaggaggtcc
     3901 ctcgtttatg tttaaccatg ctcatagcga ttcctctctt tacgatctgc ttttcgtgca
     3961 ctgatgattc gaataatttc atttccgctt tcgaaacgga tggtatgcgc aaccagaata
     4021 accacgatgc cgtaaaccag gccgattgtc tgccagcgat actcaccgtt ttctatgcgt
     4081 tcttgctgtg acaaatgttg tggatcatca aacaataaca ccgcatcttc aaagcggatg
     4141 ccatgtttca cccgattact tttggccttg ttttcatccc attcaaactc cattggcata
     4201 attgccatcc ctaattgtat atacaaaaat gtatctacaa ttattctgca attatagcgt
     4261 tgatgttgga aatagcatca cgtttcgaat aatcaaccat gaaattgaca atgagtaagt
     4321 tggacttgat tcatccaata gaatttctcg cctgacatgg cacactaaac acctcgctgt
     4381 cgggtaatga ctccaactta ctgatagtgt tttatgttca gataatgccc gatgaccttg
     4441 tcatgcagct ccaccgattt tgagaacgac agt
//
LOCUS       DAPOAV010000188         4422 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.192, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000188 DAPOAV010000000
VERSION     DAPOAV010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4422)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4422)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4422
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.192"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            102..1646
                     /locus_tag="RN951_004414"
     CDS             102..1646
                     /locus_tag="RN951_004414"
                     /inference="COORDINATES: protein motif:HMM:NF024832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HDX2529296.1"
                     /translation="MKNYDVFYGGIFKTITDYKLLKIQKDIKNNMTALVSSFKWVGIG
                     QLVKIATQLVSLFYLTHLIPPSSYGLLAMSSVVMNLASIFNDMGTGAAVIQRQEASIG
                     FYNYIYRINIFTGLFVMLLVIITSPLIVVYFNTPELYPVLFLLAFSFPISSLTITHKA
                     KLEKEMNFKVIIAIEIFSSLTGMVLAIVLANLGFGVYSLIFQTLTTISISTICFLKVS
                     GLSLSLRIKNISHSDKSGVIGFSGYLLSFNLINYFSRNLDSILIGRFFSSAILGVYSI
                     AYRIMLFPLQSLTLVFSRVFLPHLSKNINNTNNTNKQDYLNALKLILSLSAPLMLGLS
                     ATSFSFTRIFFDPKWHLLGDLLHWLAPTAIIQSALSTTGSVFMAYGKTRWLFFLGCIG
                     AFLMGLSFIIGVHFDIKTLVYLYFFANLINSLPAFILLKNILKFSYIELVNVFFRTIS
                     PAFLMFLLIKVWQHFSFFKNASIDFSFNVALGIFSYIVFYTLFNFNEVVRTGVIHKLR
                     CMTKLK"
     gene            complement(1739..2003)
                     /locus_tag="RN951_004415"
                     /pseudo
     CDS             complement(1739..2003)
                     /locus_tag="RN951_004415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558268.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
     gene            complement(2148..3024)
                     /locus_tag="RN951_004416"
                     /pseudo
     CDS             complement(2148..3024)
                     /locus_tag="RN951_004416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016946055.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            complement(3223..3507)
                     /locus_tag="RN951_004417"
     CDS             complement(3223..3507)
                     /locus_tag="RN951_004417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX2529297.1"
                     /translation="MSFFDELKASLEEAVEIKNGTKAPARVTRYELADVRAIRENLNI
                     TQSEMAKVLGTSLDTIKSWETGRRNPTGLAAKVLATIQANPKFFDELAAH"
     gene            complement(3509..3841)
                     /locus_tag="RN951_004418"
     CDS             complement(3509..3841)
                     /locus_tag="RN951_004418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015873600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDX2529298.1"
                     /translation="MSHAIEFIETTMFTRQIKQIATDDEIKELQKELIESPDKGDLIQ
                     KTGGLRKIRMATGNQGKSGSARVIYFLATAEVIYLVMAYPKSTKDSITDAEKAELKKL
                     TQRLKDEV"
     gene            complement(3986..4222)
                     /locus_tag="RN951_004419"
     CDS             complement(3986..4222)
                     /locus_tag="RN951_004419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006674368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbeD family mobilization/exclusion protein"
                     /protein_id="HDX2529299.1"
                     /translation="MTEMERQLLSALESLQTSYEQQKQAWQDSYSSLQRMFETTSQAL
                     ERNDRVCLNLSNQVNALHEQVERLSSDLSRLTRS"
BASE COUNT         1064 a          952 c          952 g         1454 t
ORIGIN      
        1 ctattggtgg agatgatcat aatgccttat aatcatacgg gatacgaact tataaagtcc
       61 taaagtttag ctaaatcgga atctacaacg tagatgatag cttgaagaat tatgatgtct
      121 tttatggtgg tatctttaaa accatcacgg attataaatt attgaaaatt caaaaggata
      181 ttaaaaacaa tatgactgca ctagtcagta gttttaaatg ggttggcatt ggacaacttg
      241 taaaaatagc aacacaattg gtttcgttat tctacttgac gcacttaatc cccccatcga
      301 gctatggact attagcaatg tcatctgtgg ttatgaattt agcaagcata ttcaatgaca
      361 tgggaactgg ggcggcagta attcagcgac aagaggcgtc gatcggtttt tataattaca
      421 tatacaggat aaacattttt actgggttgt ttgttatgct gcttgtaata ataacatccc
      481 cattaattgt cgtgtacttt aacacacccg agctataccc ggttctattt ctattggctt
      541 ttagctttcc aatttccagc ttaacaataa ctcacaaagc aaaattagaa aaagaaatga
      601 actttaaagt catcattgca attgaaattt tctctagcct tacaggaatg gtgctggcaa
      661 tagttttagc taatttaggc tttggtgttt atagtttgat ttttcaaaca ctgacaacaa
      721 tatcaatatc cacaatatgt tttttgaagg tttccgggtt gagtttatca ttgagaatta
      781 aaaatatcag ccatagtgac aagtcaggag ttatagggtt tagtggttat ttattgtctt
      841 ttaatttaat aaattatttt tccaggaatc ttgattctat tttaataggc cgttttttct
      901 catccgcaat acttggggtc tattcgattg cctaccgcat tatgttattt ccgttgcaga
      961 gcctgacgct tgttttttct agagttttct tgccacacct tagcaaaaac ataaataaca
     1021 ctaataacac taataaacaa gattacttaa atgcattaaa acttatacta tcattaagcg
     1081 cgccactgat gctaggttta tctgctacat ctttttcttt tacgaggatt ttctttgatc
     1141 ctaagtggca cctacttgga gacttattgc attggttggc acctacagcg attatccaat
     1201 cagccttgag tacaacaggt tctgttttta tggcctacgg aaaaacaagg tggttgtttt
     1261 tcttaggttg cattggcgct tttttgatgg ggttgtcttt cattataggt gttcatttcg
     1321 atataaaaac attggtctac ctttattttt ttgcaaactt aattaattca ctcccggcat
     1381 ttattttact taagaatatc ttgaagttta gttacattga attggtaaac gtgtttttta
     1441 gaactatctc cccagctttt ttgatgttct tacttattaa agtatggcag catttttcct
     1501 ttttcaaaaa tgccagcatt gatttttctt ttaatgtcgc attgggtatt tttagttata
     1561 ttgtttttta taccttgttt aatttcaatg aggttgttag gacaggagta attcataagt
     1621 taagatgcat gaccaagtta aagtgattca tttattaaat tcattaaatg aattggtaat
     1681 gactccaact tactgcttgt gttttatgtt cagataatgc ccgataccga cttcggccta
     1741 atttttttaa gtgtcgtaaa atcgtgttga ggacagtgcc cataatgcgg gatgtggccc
     1801 ggcatccaac gccattcatg gccatatcaa tgattttctg gtgtgtaccg ggctgagagg
     1861 cggtgtaagt gaactgtagt tgcttgctat gttttacgac agtgagagca gagatagcgt
     1921 tgatgtccgg tagtgctttt accgttacgc accacgcctt cagtagctga acaggaggga
     1981 taactgatgg aaatggaagc cacgggagca cctcaaaaac accattagac actaaaccag
     2041 caagttggca tcatcacaaa cagttgttac tgctggaaaa aaaacactat caacacttaa
     2101 gtaatggtga ttcaataatt aagattcagt atgtaaaata ctgaatctta attataaatt
     2161 ttcctttttc taaaaaatgt agcgcgacta atacctaaag caacccaagg ctcccctaga
     2221 gacagcctac ctcctcctga tgatttttca ccaccaactt ttcctctttt ggcttgtata
     2281 agtgaaaaat tttgcttatt aaatttcaaa aatgtccact tgcagatact tttcgctatt
     2341 cccgttactt cattctcatt caaaggcact gcaaattgca gattgtaagc gcaggcgcgt
     2401 tcatggcagg cttgtagcca ctgttcgtac tcaggccagc cctgacggat agcgcgatat
     2461 gcccactttc tggttttatc aaacagtatg cagttacgac ctaagccata atcggcgacg
     2521 atttttttat cgttcgcagc gttcaggtcg agtgattcgg ctaaccagtc cagcgtgtag
     2581 agttcaggct gccatacggg caattttcca gtgactgtgg ttcggattct tgcaaattag
     2641 ccccgaatac cccgtgtcag cgcccaattt tttacgtagc gcgctctcta cagcagcggc
     2701 gtaacgtaac ggtttcattt ttccgtctgg cgcggtgcgt atcgaggttt tcagtgcgta
     2761 cagcaggtgc gcgtgtccgt tttcggggtt ggtgatggtc agtgtcggcg cgggggcgtt
     2821 gcggtcgctc cagtcaatgg ctgcgccgat gcggtcaacg tcaaatccca gccagaacat
     2881 ggcgtgaggc tgattaaact ggatgtattt agccagaata gcgcgctctt tccctgcgat
     2941 gcggacacca aagtgtaaat catccgagaa gtacggttta tgcggcaagc ggtcgttgaa
     3001 aagttcgagt gctgcgttac gcaatgtgcc ctgaacttat ggcgggctgt tgtctggcac
     3061 ggttcatgtg ctaatatcct tcttaggttt tatacctagc cctgatttat catgtctctt
     3121 ccgccaagtt gaaatcatga ttatcggggc tttgtttttt ctgttgccgt taaagttaca
     3181 cgcgaacggc ctcgcctgtc gaatttcttc tgtcacatca gcttaatgcg ccgccagttc
     3241 atcaaaaaac tttgggttag cctgaatggt ggccagcact tttgctgcca gtccggttgg
     3301 gttacggcgt ccggtttccc agcttttgat ggtatcgagg ctggttccca gcactttcgc
     3361 catttcgctc tgagtaatat tcaggttttc tctgatagcc ctgacgtctg ccagctcgta
     3421 gcgggtcaca cgggcggggg ctttggttcc gtttttgatt tcaacggcct cttccagaga
     3481 ggctttcagc tcgtcaaaaa aactcatctt acacctcgtc tttcagtcgt tgggtcagct
     3541 tcttcagttc tgctttctct gcgtctgtga tgctgtcttt ggtgctttta gggtaggcca
     3601 tcaccagata aatcacctct gcggtggcaa ggaagtaaat cacccgcgca ctgccgctct
     3661 ttccctgatt ccccgtcgcc atcctgatct ttcgcagacc gcccgttttc tggatgaggt
     3721 cacctttgtc cggtgactcg ataagctctt tctgaagctc tttgatctca tcatccgtgg
     3781 cgatttgctt tatctgacgg gtaaacatcg ttgtctcgat aaactcaatc gcgtgactca
     3841 cggctgtctc ctgtatattt tgatgtacaa tgtacaccaa gaggcgtgtt ctgaaaagcc
     3901 gcgttctgtg ccatcagacg ttacatggac tgacctcgat agcgggttgc ttgcttctcc
     3961 tgctgtaact gccgttcctg ctgctttacg agcgtgttaa tcggctcaga tcgctgctca
     4021 agcgttcgac ctgttcgtgc aaggcgttca cctgattgct caagttcaga cataccctgt
     4081 cgttgcgctc cagtgcctgt gaggtagtct cgaacatgcg ttgcaagctg ctgtaactgt
     4141 cctgccacgc ctgcttctgc tgttcgtagc ttgtttgtaa gctttctaag gcgctcagaa
     4201 gctgcctttc catctcggtc atggtttttc ctgtcctcag tgataaaaac gtgctgtggc
     4261 gtttctgtgg tgtctgacgg ggttatttcg cggtgtactt catcacggtg tttccggctg
     4321 tcgatgtgta tgtctcggtg ccatgcgctt tcttcggcag taccaccaga taggtgttct
     4381 tctgcttgtc gtccttgtaa atcgctaccc ctgcgccgct ct
//
LOCUS       DAPOAV010000189         4373 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.193, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000189 DAPOAV010000000
VERSION     DAPOAV010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4373
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.193"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(163..676)
                     /locus_tag="RN951_004420"
                     /pseudo
     CDS             complement(163..676)
                     /locus_tag="RN951_004420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566943.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4113 domain-containing protein"
     gene            complement(737..841)
                     /locus_tag="RN951_004421"
                     /pseudo
     CDS             complement(737..841)
                     /locus_tag="RN951_004421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544830.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            complement(843..1166)
                     /locus_tag="RN951_004422"
                     /pseudo
     CDS             complement(843..1166)
                     /locus_tag="RN951_004422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000952428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1912..2889
                     /locus_tag="RN951_004423"
     CDS             1912..2889
                     /locus_tag="RN951_004423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052630.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDX2529300.1"
                     /translation="MDKSSGELVTLTPNNNNTVQPVALMRLGVFVPTLKSLKNSKKNT
                     LSRTDATEELTRLSLARAEGFDKVEITGPRLDMDNDFKTWVGIIHSFARHNVIGDKVE
                     LPFVEFAKLCGIPSSQSSRRLRERISPSLKRIAGTVISFSRTDEKHTREYITHLVQSA
                     YYDTERDIVQLQADPRLFELYQFDRKVLLQLKAINALKRRESAQALYTFIESLPRDPA
                     PISLARLRARLNLKSPVFSQNQTVRRAMEQLREIGYLDYTEIQRGRTKFFCIHYRRPR
                     LKAPNDESKENPLQPSPAEKVSPEMAEKLALLEKLGITLDDLEKLFKSR"
     gene            complement(3174..3914)
                     /locus_tag="RN951_004424"
     CDS             complement(3174..3914)
                     /locus_tag="RN951_004424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDX2529301.1"
                     /translation="MNNVIPLQNSPERVSLLPIAPGVDFATALSLRRMATSTGATPAY
                     LLAPEVSALLFYMPDQRHHMLFATLWNTGMRIGEARMLTPESFDLNGVRPFVRILSEK
                     VRARRGRPPKDEVRLVPLTDISYVRQMESWMITTRPRRREPLWAVTDETMRNWLKQAV
                     RRAEADGVHFSIPVTPHTFRHSYIMHMLYHRQPRKVIQALAGHRDPRSMEVYTRVFAL
                     DMAATLAVPFTGDGRDAAEILRTLPPLR"
     gene            complement(4035..4223)
                     /locus_tag="RN951_004425"
     CDS             complement(4035..4223)
                     /locus_tag="RN951_004425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001309252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HDX2529302.1"
                     /translation="MASDTFSCRRRLSAGFFSVSACSWHYPNSPKNGKPALSPRHDWL
                     NTGSLLQNIPLRIWFYPQ"
BASE COUNT         1056 a         1102 c         1065 g         1150 t
ORIGIN      
        1 ctttttcggt tgaaaagaaa ttgattgaat tactggaaaa acaatctggt ctccatacgt
       61 ctgtggattg cagtactccc cttacagagc agagtctgtc gagaaatgac ggtgaagacc
      121 agaccagaag aaacgctgaa aatatgttcg gagatgactg aactaaccca gcctggccag
      181 gggaatatct cgccatttag ttgtataaca ctgactcaac atttcccgtt tcatttgcca
      241 ttcaggggcg gttcctcgcc ccgcaaacca cactttccct tttcccgact ggttcagttc
      301 atcgagtgtt ttcattaact tttcactgtt tttacggggc tggatttcat caaataatcc
      361 cggctgcgct atacccgatg gtgtgaaatc agccagcatg actcctgcct tcatatagcg
      421 gtacccttca cgccagacat ggtttaaggc tctgcatgcg gcggcaataa tgtcccggct
      481 gtcctgtgtg ggcaatgaaa gcttttccac agcggcattg ctgtaacagg gttcaggggg
      541 atgtccgtac aaatgtcgtc acctgccggc aatactgacg ctccccacgt agtttctctg
      601 cggcccgctc tgcatactga acaacagcct ggtgcatggc atctttgtct gtgattcgtt
      661 caccaaaact gcgactatgt caacgccacg atgtttgacc gttatttgcc attttcatgc
      721 ccgctaaata ctttcgttac tgatgctgtc cgctttgcac catttcatca tcactgattg
      781 gcgttgtgtt tttggtcagc actccagctt tacgtttctc ttttaaccgg taactctctc
      841 cttgttcttt ttgacggacg cattttacgt ttgggctgga tgtagtaacg cagcatggaa
      901 cgtccgcccg tataacccat tgccttaatc tccgcgaaga taacctcgct attccagaca
      961 ttctctgcca ggcgcatgtc gatgtaatcc ataaacggtt tcagcttaac cattttgtgg
     1021 cgggtctttc tggctggcgg ttcagggtat ttgaggtagc gtctgaccgt ccgttcagag
     1081 caaccaatct gagccgcaat atcgacaatg tacgcgccct gctggcgcat ttgctttatc
     1141 atgtaaaagt cctctctgct cagcatgttg atgtcctttc tggtgtgaga accttaagga
     1201 aacaacatgt tgggtggagc ggacaatcca aatggtgaat taccgtctta tatcactggc
     1261 gctgacacct gtagtttgta tacacaatcc ctggcattga aacacacata tgaagtgtac
     1321 ttcggatatg accgtacgct caggaagtac ggcagattcc gtcaaaaatt acctgtaaag
     1381 acagacatca gaaaaaacag tgctcgccgc agaccggtga ccgggcgaag cccgcgaacc
     1441 ggcgaggaag cgcaatgtat ctgtagttac agggagcagg tacgccctga agccctttca
     1501 taaaacggtt gtgtgcgctg tccttctgga atgatttatc cacatatccg gaggcccgat
     1561 ccagtaaaca gatccatgaa tgatcaacaa aggatccatt aaagatcccc atatcgctgc
     1621 aaaccttgtc actcatgggc cgggaccacg atcacataag ctgtggcatg ttactgataa
     1681 actgtaacat gctaatgata agctgtattc agtaatccat atactgaagt aagttaatga
     1741 cataaactat ggtcagtatg ccagactcag ttgttaaata caggctgcag gtttttcttc
     1801 agtcagttag cggagttctg acacacgatt ttctgtttat tcttttactg tccacaggct
     1861 ggaggctttc tggaaaacga aaattcagac atcaaaaaac tgttcggcga ggtggataag
     1921 tcctccggtg agctggtgac actgacacca aacaataaca acaccgtaca acctgtggcg
     1981 ctgatgcgtc tgggcgtttt tgtaccgacc cttaaatcac tgaagaacag taaaaaaaat
     2041 acactgtcac gtactgatgc cacggaagag ctgacacgtc tttccctggc ccgtgctgag
     2101 ggattcgata aggttgagat caccggcccc cgcctggata tggataatga tttcaagacc
     2161 tgggtgggga tcattcattc ctttgcccgc cataacgtga ttggtgacaa agttgaactg
     2221 ccttttgttg agtttgcaaa actgtgtggt ataccttcaa gccagtcatc ccgcaggctg
     2281 cgtgagcgca tcagcccttc cctgaagcgc attgccggta ccgtgatttc gttttcccgt
     2341 accgatgaga agcacacccg ggaatatatc acccatctgg tacagtcagc ttactacgat
     2401 actgagcggg atattgtgca gttacaggcc gatccccgcc tgtttgaact gtaccagttt
     2461 gacagaaaag tccttctcca gcttaaggcg attaatgccc tgaagcgacg ggagtccgcc
     2521 caggcactct acacctttat agagagcctg ccccgggatc cggcaccgat atcgctggcg
     2581 cggctgcgtg cacgcctcaa tctgaagtct cctgtatttt cccagaacca gacggtcaga
     2641 cgggcaatgg agcagttgcg cgagattgga tatcttgatt acacggagat ccagcggggg
     2701 cggacaaaat tcttctgtat tcactaccgg cgtccccggt taaaagcgcc gaatgacgag
     2761 agtaaggaaa atccgttgca accttcacct gcggaaaaag tcagtccgga gatggcggag
     2821 aagcttgccc tgcttgagaa actgggcatc acgctggatg acctggaaaa actcttcaaa
     2881 tcccgctgaa cataaactgt agtcagtgaa gagcgctcct ttactgacta cagcttatat
     2941 taaccggtgc agtgagtggt ctgctcactg cagtttatat tctgtttcct gcagtgctgt
     3001 ctgtagctga gctgccatct gcctgtccct tacgtaagtg atcccgtaac ctgatgctga
     3061 ggcattgctc ccttcataaa acatgactta ctcactacag cttatataca tgctccagct
     3121 tatgttatgt ctgttctgct gaccacagct tatataagga agcgcgtatg ccgtcacctc
     3181 aggggaggca gtgtacgcag gatctccgca gcatcccgcc cgtcacctgt gaaaggcact
     3241 gccagcgtgg cagccatatc cagtgcaaac actctggtat aaacctccat cgaacgtgga
     3301 tccctgtgac cagccagtgc ctggatgact ttccggggct ggcggtgata gagcatgtgc
     3361 atgatatagc tgtgccggaa ggtgtgtggt gtgaccggaa tcgaaaagtg taccccgtca
     3421 gcttcggccc gtctgacagc ctgcttcagc cagttgcgca tggtttcgtc ggtcacggcc
     3481 cataatggtt cacgacgacg gggccgggtg gtgatcatcc agctttccat ctgcctgaca
     3541 tagcttatat ctgtcagcgg caccagtcgc acttcatctt ttggcgggcg tccgcgtcgc
     3601 gcacgcactt tttcggacag gatccgcaca aacggtctta ctccattcag gtcaaatgat
     3661 tccggcgtca gcatccgggc ttcgccaata cgcattccgg tattccagag ggtggcgaac
     3721 agcatatggt gacgctgatc cggcatatag aagagaaggg cactcacttc cggggccagc
     3781 aggtaggccg gtgtggcccc cgtggaagtg gccattcttc tcagggagag cgctgttgca
     3841 aaatccaccc ccggcgcaat gggtaacagg gagacgcgtt ctggtgaatt ctgcagggga
     3901 atgacattgt tcatgagtta tttttcacgt agcacacgca ctgtttatgg atacaggtat
     3961 tctgacctga acgcccggat ccttccacga caataaatcg cagcgcgcgg atccttttgt
     4021 ttgcttatca cgcattattg cgggtaaaac caaatacgta aaggtatgtt ttgcagcagg
     4081 gatcccgtat taagccagtc gtggcgcggg ctgagggctg gtttgccgtt tttgggagaa
     4141 ttggggtaat gccaggaaca ggcagatacg gagaaaaatc ctgcagataa ccttctacga
     4201 caactgaagg tgtctgacgc catattctta gctacttctc agttttaagg cggcttagtc
     4261 acaacataag gttatgcata ataagcatat tttattatgt tatgttatgg tcttgttcat
     4321 gcatgaactg ttatctattc agtcactttt aacgttttat atcatactgc ata
//
LOCUS       DAPOAV010000190         4369 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.194, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000190 DAPOAV010000000
VERSION     DAPOAV010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4369
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.194"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            126..1781
                     /gene="tsr"
                     /locus_tag="RN951_004426"
     CDS             126..1781
                     /gene="tsr"
                     /locus_tag="RN951_004426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HDX2529303.1"
                     /translation="MLKRIKIVTSLLLVLAVFGLLQLTSGGLFFNALKNDKENFTVLQ
                     TIRQQQSTLNGSWVALLQTRNTLNRAGIRYMMDQNNIGSGSTVAELMQSASISLKQAE
                     KNWADYEALPRDPRQSTAAAAEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQGYQ
                     DGFEKQYVAYMEQDDRLYDIAVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASL
                     VAPMNRLIDSIRHIAGGDLVKPIEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANA
                     IYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSAS
                     ETAQRGGKVVDNVVQTMRDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQ
                     GRGFAVVAGEVRNLAQRSAQAAREIKSLIEDSVGKVDVGSTLVESAGETMAEIVSAVT
                     RVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRL
                     TEAVAVFRIQQQQRETSAVVKTVTPAAPRKMAVADSEENWETF"
     gene            complement(1830..3191)
                     /locus_tag="RN951_004427"
     CDS             complement(1830..3191)
                     /locus_tag="RN951_004427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2529304.1"
                     /translation="MEKENITIDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAM
                     LLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLD
                     RKGPRLMLRLGMFFWSLFQAMSGMVYNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFN
                     IKERGRPMGFFNAASTIGVAVNPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYR
                     NREHVELTAVEQAYLNAGSVNARRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLY
                     LAWLLGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRKIC
                     IIAGMFCSAAFTLVVPQATTSMTAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASV
                     GSIQNFASFICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQPINDP
                     RKD"
     gene            complement(3406..4320)
                     /locus_tag="RN951_004428"
     CDS             complement(3406..4320)
                     /locus_tag="RN951_004428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDX2529305.1"
                     /translation="MSRSQNLRHNVINQVIDDMARGHIPSPLPSQSALAEMYNISRTT
                     VRHILSHLRECGVLTQVGNDYVIARKPDHDDGFACTTASMSEQNKVFEQAFFTMINQR
                     QLRPGETFSELQLARAAGVSPVVVREYLLKFGRYNLIHSEKRGQWSMKQFDQSYAEQL
                     FELREMLETHSLQHFLNLPDHDPRWLQAKTMLERHRLLRDNIGNSFRMFSQLDRDFHS
                     LLLSAADNIFFDQSLEIISVIFHFHYQWDESDLKQRNIIAVDEHMTILSALICRSDLD
                     ATLALRNHLNSAKQSMIRSINENTRYAH"
BASE COUNT         1149 a         1035 c         1173 g         1012 t
ORIGIN      
        1 gtaaataatg gctttttaaa ttcagagtgt gaataaaatt actcggcgta atctccgcgg
       61 gatattcata aagtttttcc tttccaggcc gaaaatcttg catcggtcca caggaaagag
      121 aaaccatgtt aaaacgtatc aaaattgtga ccagcttact gctggttttg gccgtttttg
      181 gccttttaca actgacatca ggcggtctgt tctttaatgc cttaaagaat gacaaagaaa
      241 atttcactgt tttacaaacc attcgccagc agcaatccac gctgaatggc agctgggtcg
      301 cgttgttgca gacgcgtaac accctcaacc gcgcgggtat ccgctacatg atggatcaga
      361 ataatattgg tagcggttca accgttgctg agctgatgca gagtgccagt atttcgctga
      421 aacaggcgga aaaaaactgg gcggattacg aagcgttgcc gcgtgacccg cgtcagagca
      481 ccgccgcagc ggcagagatc aaacgtaatt acgatattta tcacaatgcg ctggcggagc
      541 tgatccaact attaggtgca ggcaaaatca acgagttctt tgatcagccg acccagggat
      601 atcaggacgg tttcgagaag cagtatgtgg cttacatgga gcaagacgat cggctctatg
      661 atatcgccgt cagcgataac aatgcctcct acagccaggc gatgtggatt ctggtgggcg
      721 tgatgatcgt cgtactggcg gtcatcttcg ccgtctggtt cggtattaaa gcctcgctgg
      781 tagcgccaat gaatcgcctg attgacagca ttcgtcatat tgcaggcggc gatctggtga
      841 aaccgattga ggtggatggc tctaatgaga tggggcaact ggcagagagt ttgcgccata
      901 tgcaaggaga gctgatgcgt accgtcggtg atgtgcgcaa cggggccaat gccatctata
      961 gcggtgccag cgaaatcgcc accggcaata acgatctctc ttcgcgcacc gagcaacagg
     1021 ccgcttcgct ggaagagacg gcagccagca tggagcaact gaccgcaacg gtgaaacaga
     1081 acgccgagaa tgcgcgtcag gccagccatc tggcgttaag tgcttctgaa acggcgcaac
     1141 gcggcggcaa agtggtggat aacgtagtac agaccatgcg cgatatctcc accagttcgc
     1201 agaaaatcgc cgatattatc agcgtaattg acggcattgc cttccagacc aatattctgg
     1261 ctttgaacgc ggcggttgag gctgcgcgtg cgggtgagca agggcgcggt tttgcggtgg
     1321 tcgcgggaga agtgcgtaat ctggcccagc gcagcgccca ggcggctcgt gaaattaaaa
     1381 gcctgattga agactcggtg gggaaagtgg atgttggctc tacgctggtc gaaagcgccg
     1441 gggaaacaat ggcggagatt gtcagcgccg tgacccgcgt gacggacatt atgggcgaaa
     1501 ttgcttctgc ttctgatgag cagagccgtg gtatcgatca ggttggctta gcggttgctg
     1561 agatggaccg ggtaactcaa cagaacgccg cgctggtgga agagtctgcc gctgccgccg
     1621 ccgcgctgga agagcaggcc agtcgcctga ccgaagcagt ggcagtgttc cggattcagc
     1681 aacagcagcg tgaaacatcg gctgtggtaa aaaccgtgac gccagctgcg ccgcgtaaaa
     1741 tggccgtggc agatagcgag gagaactggg aaacatttta atcgccatga aaatgcccga
     1801 taagcaaaat gttatcgggc ataaggagat taatctttac gtgggtcgtt gatcggctga
     1861 cgaaccagga agatgtacgc cagtgccccc gctgcggtga cgcaaccgca gatgattagt
     1921 gccagacgga atgagtgggt ggtatcaaca ataaaaccag taatgatcgg cgcaaaagag
     1981 gcgcagatga agctggcaaa gttctggata ctgcccaccg acgcagtcat gcgagaagca
     2041 actgcgacgt ggatcaagcc ccagcaggat gttccggcaa agtgaataca gaacagtgcc
     2101 atgccaatca gcagaaccgc tgtcatggat gttgtcgctt gcggtacgac cagcgtaaag
     2161 gcggcagaac agaacatccc ggcaataatg cagatcttac ggcttttaat cggagccatt
     2221 ccccctttga ccagccagtc agtaacgtaa ccgttgacca gcatcccggc agccccaaac
     2281 aggaaaggga tagccgccat caaccctgtg ctttttaaat ccaggttata ggctgtttgc
     2341 aggtaaccaa gaagccaggc cagatacagc cacgcagtgt agttgatgcc actgaatccg
     2401 agcatcattc cccacattgt acggttacgg aacaggctgc gccattcggc aaaactgagc
     2461 ggatctcggc gggcattgac gctacctgca ttgagataag cttgctcaac ggcagtcagt
     2521 tctacgtgct cgcggttgcg atagagcata taccagccga tggcgagaaa aatccccagt
     2581 acaccaatgg taataaacat cccgcgccag cccatcacca gcatcatcgc cgccagaatc
     2641 ggtgggttta cggcaacgcc aatggtagaa gctgcgttga agaagcccat cgggcgtccg
     2701 cgctctttga tgttgaacca gtcgttaatg acttttacac cgcatgggtt catcggcgct
     2761 tcaccaatcc ccataccgat acgcaccaac acgaactgcg taaagttgta caccatgcca
     2821 gacattgcct ggaacagtga ccagaagaac atccccagtc tcagcatcag gcgtgggcct
     2881 ttacgatcca atagtgggcc gcaaggaagt tgcgcaatcc cgtaagcgag tgaaaacacg
     2941 gagagcaaag cgccgatttc ggtggcactt aatcccaatt cttcacgaat cgttaaattt
     3001 gctaccgaca gcgaactgcg gtcgagataa ttgattaccg ccgcaaaaaa taataacaac
     3061 atggcggtgg tttgaatgcg tttaattcgg gtactgcgtt gaactaatcc atctggtggc
     3121 acgggaatat ctgccgacga agatggagta aatgaagaac gcggatcgat ggtgatattt
     3181 tctttttcca cgccggactc ctgtatttat aattttaatt gtttacgtaa ttgtgcatta
     3241 cgcaaggttg acattaacgg caggttaaag ttttaggact ttactaccgc tcacaaaaac
     3301 atttttagtc gactgattgt gagcataggt aagcgggaat ttcccggtat ttatcttttg
     3361 ataaaaccgt gcacccgcta atagtttgct gtttttaatc cgtacttaat gagcataacg
     3421 cgtgttctca ttaatggatc gaatcattga ttgtttagct gaattcaaat ggttacggag
     3481 cgcaagggtg gcatcaaggt cactgcggca aatcagagcg ctgagaatgg tcatatgctc
     3541 atcgacggca atgatattgc gctgtttaag atcgctttcg tcccattgat agtgaaaatg
     3601 aaagatgact gaaatgatct caagcgattg atcaaaaaag atattgtcgg cagccgaaag
     3661 cagtaaggag tgaaaatctc tgtcaagttg cgagaacatg cgaaagctat tgccgatgtt
     3721 gtcacgcagt agccgatgac gttcgagcat ggttttcgcc tgcagccagc ggggatcatg
     3781 atcaggcagg ttgagaaagt gctgaagtga atgtgtttcg agcatttcgc gtagctcaaa
     3841 cagctgctcg gcgtaggatt gatcgaattg cttcatgctc cactggccgc gcttttcgct
     3901 gtgaataaga ttataacggc cgaattttaa aagatattct cttactacaa ccgggctgac
     3961 acccgcggcc cgcgccagtt gcagttcaga aaatgtttcc cctgggcgta actggcgctg
     4021 gtttatcatc gtgaaaaaag cctgctcaaa cactttgttt tgttcactca ttgaagcggt
     4081 agtacaggcg aaaccgtcat cgtggtcagg tttacgcgca ataacatagt cgtttccaac
     4141 ctgcgtcaag acgccgcatt cgcgtaaatg gctgagaata tgacgcactg tggtgcggct
     4201 gatgttgtac atttccgcca gcgcactttg cgatggaagt ggggaaggga tatgaccccg
     4261 cgccatatca tcaatgacct ggttaatcac attgtggcgt aaattttgtg aacgactcat
     4321 attttcctcc ttgtgagtcc attaaaaccc gatttaaaac atttttatg
//
LOCUS       DAPOAV010000191         4257 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.195, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000191 DAPOAV010000000
VERSION     DAPOAV010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4257
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.195"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..1210)
                     /locus_tag="RN951_004429"
     CDS             complement(<1..1210)
                     /locus_tag="RN951_004429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001735687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HDX2529306.1"
                     /translation="MKLNARQVETAKPKDKTYKMADGGGLYLEVSAKGSKYWRMKYRR
                     PSDKKEDRLAFGVWPTVTLAQARAKRDEAKKPLVQGIDPKAEKKEAQAENSGAYTFET
                     IAREWHASNKRWSEDHRSRVLRYLELYIFPHIGSSDIRQLKTSHLLAPIKKVDASGKH
                     DVAQRLQQRVTAIMRYAVQNDYIDSNPASDMAGALSTTKARHYPALPSSRFPEFLARL
                     AAYRGRVMTRIAVELSLLTFVRSSELRFARWDEFDFDKSLWRIPAKREEIKGVRYSYR
                     GMKMKEEHIVPLSRKAMVLLEQLKQISGDKELLFPGDHDATKVMSENTVNSALRAMGY
                     DTKTEVCGHGFRTMARGAMGESGLWSDDAIERQLSHSERNNVRAAYIHTSEHLDERRL
                     MIQWWADYLDE"
     gene            complement(1374..1458)
                     /locus_tag="RN951_004430"
     tRNA            complement(1374..1458)
                     /locus_tag="RN951_004430"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1422..1424),aa:Leu,seq:caa)
     gene            1654..2673
                     /gene="ahr"
                     /locus_tag="RN951_004431"
     CDS             1654..2673
                     /gene="ahr"
                     /locus_tag="RN951_004431"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418690.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent aldehyde reductase Ahr"
                     /protein_id="HDX2529307.1"
                     /translation="MSMIRSYAAKEAGGELEVYEYDPGELRPQDIEVQVDYCGICHSD
                     LSMIDNEWGFSQYPLIAGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDAC
                     ISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKP
                     LLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVN
                     SRDPQALKALSGQFDLIINTVNVSLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLI
                     AGDRSISGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAIQHVRDGKARYRVV
                     LKADF"
     gene            2801..>4257
                     /locus_tag="RN951_004432"
     CDS             2801..>4257
                     /locus_tag="RN951_004432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 domain-containing protein"
                     /protein_id="HDX2529308.1"
                     /translation="MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLA
                     ESLSEIGVPVFMADVKGDLTGIAQAGTASEKLLTRLKNIGVNDWQPHANPVVVWDIFG
                     EKGHPVRATVSDLGPLLLARLLNLNDVQSGVLNIIFRIADDQGLLLLDFKDLRAITQY
                     IGDNAKSFQNQYGNISSASVGAIQRGLLSLEQQGAAHFFGEPMLDIKDWMRTDANGKG
                     VINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAP
                     QVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRTFTPKDQKAV
                     KAAAQTMRVNPAFDTEKAIQKLGTGEALISFLNAKGSPSVVERAMVIAPCSRMGPVTE
                     DERNGLINHSPVYGKYEDEVDRESAYEMLQKGFQASTEQQNNPPAKGKEVAVDDGILG
                     GLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQ"
BASE COUNT         1020 a         1048 c         1157 g         1032 t
ORIGIN      
        1 actcatcaag ataatcagcc caccactgaa tcattaaacg tcgttcatcc aaatgctcag
       61 aagtatgaat ataagctgca cgcacgttat tacgttctga atggctcagc tgtcgctcta
      121 tcgcgtcatc actccacaac cctgactcac ccatagcacc gcgcgccatc gttctgaatc
      181 catgcccgca aacttcagtt ttcgtgtcat agcccatcgc acgcaatgcg ctgtttaccg
      241 tgttttcact cataacctta gttgcgtcat gatcccccgg gaacagtagc tctttatcac
      301 cactaatttg cttgagctgc tctaataaaa ccatagcctt ccgactgaga ggaacaatat
      361 gctcctcttt cattttcatg ccacgataag agtaacgcac gcccttaatt tcttctcgct
      421 ttgcaggtat acgccaaaga gatttatcga agtcgaactc atcccaacgc gcgaaacgca
      481 actcactgga acgcacaaaa gttagtaagg aaagctcaac cgcgattcgt gtcattacac
      541 ggccacgata tgcagcaaga cgtgcaagaa actcagggaa tcggcttgag ggtaaagcgg
      601 ggtaatgtcg cgctttggtt gtcgataacg caccggccat atcactggct ggatttgagt
      661 cgatgtaatc gttctgcacg gcataacgca taatggccgt aacgcgctgt tgcaagcgct
      721 gagcgacgtc atgctttcca ctggcatcaa cttttttaat cggggctaac aggtggctgg
      781 ttttgagctg gcgaatgtcg gacgaaccga tatgagggaa aatataaagc tcaagatagc
      841 gaagaacgcg cgatcgatga tcttcactcc atcgcttgtt actggcatgc cattcacgag
      901 caatggtttc gaaagtatat gctcccgaat tctcggcctg agcttctttc ttttcggctt
      961 ttgggtctat gccctgtact aagggctttt tagcttcatc gcgctttgct cttgcctgag
     1021 caagagtcac tgtaggccaa acaccaaaag cgaggcgatc ctcttttttg tctgaggggc
     1081 gtctgtattt catgcgccag tatttagaac ccttggccga aacctcaaga tacaaaccgc
     1141 cgccatcggc cattttgtag gttttgtctt ttggctttgc ggtctcgacc tgtctggcgt
     1201 tgagcttcat ttgggggcac atttctaatc gaagttaaga tgcccccaat tatgccccca
     1261 atgacatccg gatttcaacg gacaaccttg gacgactcag gacgtaaaaa tcgctacaag
     1321 cattgatttt taagggataa ttggaatttc tcggatggtc ttggaagtac taatggtgcc
     1381 gaaggccgga ctcgaaccgg cacgtatttc tacggttgat tttgaatcaa ctgcgtctac
     1441 cgatttcgcc acttcggcac tgaagaggta tgcggaaaac gttgtggatt atacctgtcg
     1501 cacgccacca tgcaagcgcc agcttgctcg cacctcgcta agtgctgaaa ttttcagcat
     1561 tgcatacagc gatgtgtaac ctttgtcaca ctccaggcac cccgccctgc catgctctac
     1621 acttcccaga caacaccaga gaaggaccaa aaaatgtcga tgataagaag ctatgccgca
     1681 aaagaagcgg gcggcgaact ggaagtttat gagtacgatc ccggtgagct gaggccacaa
     1741 gatattgaag tgcaggtgga ttattgcggg atctgccatt ccgatctatc gatgatcgac
     1801 aatgaatggg gattttcaca atatccgctg attgccgggc atgaggtgat tggtcgcgtg
     1861 gtggcgctcg ggagcgccgc acaggataaa ggtttgcagg tcggtcagcg tgtcgggatt
     1921 ggctggacgg cgcgtagctg tggtcactgc gacgcctgta ttagtggtaa tcagatcaac
     1981 tgtgagcaag gtgcggtacc aacaattatg aatcgcggtg gctttgccga gaagttgcgt
     2041 gcggactggc aatgggtgat tccactgcca gaaaatattg atatcgagtc cgccgggccg
     2101 ctgttgtgcg gcggtatcac ggtctttaaa ccactgttga tgcaccatat cactgctacc
     2161 agccgcgttg gggtaattgg tattggcggg ctggggcata tcgctataaa acttctgcac
     2221 gcaatgggat gcgaggtgac ggcctttagt tctaatccgg cgaaagagca ggaagtactg
     2281 gcgatgggtg ccgataaagt ggtgaatagc cgcgatccgc aggcactgaa agccctgtcg
     2341 gggcagtttg atctcattat caatactgtg aacgtcagcc tcgactggca gccttatttt
     2401 gaggcgctga cctatggcgg taatttccat acggtcggtg cggttctcac gccgctgtct
     2461 gttccggcct ttacgttaat tgcgggcgac cgcagcatct ctggttctgc taccggcacg
     2521 ccttatgagc tgcgaaagct gatgcgcttt gccgcccgca gcaaggttgc gccgacaacc
     2581 gaactgttcc cgatgtcgaa aattaacgac gccattcagc atgtacgcga tggtaaagct
     2641 cgctaccgag tagtcctgaa agccgacttc tgatcccttt gccgggtgct gtcgcccggc
     2701 acttaaatct ctttggaagg cgtctcgcaa tctgctgaat ttagcggtga agagtgcaca
     2761 gccgttgcct atactccagg caggaactgg aggaaatctc atgagcgaac ccctgttaat
     2821 tgcccgcacg ccggacacag aactgttttt actgccggga atggctaacc gtcacgggct
     2881 gattactggc gcaacgggga cgggtaaaac cgttacgctg caaaaactgg cagagtcatt
     2941 gtcggaaatc ggcgtgccgg tgtttatggc tgatgtgaaa ggcgatctga ccggtatcgc
     3001 gcaggcagga acggcgtcgg aaaaactgct cacaaggctt aaaaatatcg gcgtcaatga
     3061 ctggcaaccg catgccaatc cggtggtggt gtgggatatc tttggcgaga aaggccatcc
     3121 ggtgcgggcg acggtttcgg atctggggcc gctgttgctg gcgcggctgt tgaatctcaa
     3181 cgatgtgcaa tctggcgtgc tgaatatcat cttccgcatt gctgacgatc aggggctgtt
     3241 actgctcgac tttaaagatt tgcgggcgat tacccaatac atcggcgata acgccaaatc
     3301 tttccagaat cagtacggaa atatcagtag cgcatcggtt ggtgccatcc agcgcgggct
     3361 gttgtcgctg gaacagcaag gcgcagcaca cttctttggt gagccgatgc tggatatcaa
     3421 agactggatg cgcaccgatg ccaacggtaa aggcgttatc aatatcctca gcgccgagaa
     3481 gctttatcag atgccgaaac tgtatgccgc cagcctgttg tggatgctct cggagttgta
     3541 tgaacaattg ccggaagcgg gcgatctgga gaaaccaaaa ctggtgtttt tcttcgacga
     3601 ggcacatctg ctgtttaacg atgcaccgca ggtactgctg gataagattg agcaggtgat
     3661 aaggcttatt cgctcaaaag gcgtgggcgt ctggttcgtt tcgcaaaatc cgtccgatat
     3721 tccggataac gtgctcggcc agctcggtaa tcgcgttcaa cacgctttgc ggacttttac
     3781 gcccaaagat cagaaagcgg taaaagctgc ggcgcaaacc atgcgggtca atccggcatt
     3841 tgataccgaa aaggcgattc agaaactggg caccggcgag gcgttgatct cttttctcaa
     3901 tgcgaaagga agcccttctg tggtggaacg ggcgatggtg attgcgcctt gttcgcggat
     3961 ggggccggtg acggaagatg agcgtaatgg cttgattaat cactctccgg tgtatggcaa
     4021 atatgaggat gaggtggacc gggaatccgc ctatgagatg ttgcaaaaag gctttcaggc
     4081 cagtaccgag cagcaaaata atccccccgc gaaagggaaa gaggtagcgg tggatgacgg
     4141 cattcttggt ggattgaagg atattttgtt cggcactacc ggaccacgcg gcgggaagaa
     4201 agatggagtg gtgcagacaa tggccaaaag cgccgctcgc caggtgacga atcagat
//
LOCUS       DAPOAV010000192         4234 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.196, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000192 DAPOAV010000000
VERSION     DAPOAV010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4234
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.196"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..302)
                     /gene="traV"
                     /locus_tag="RN951_004433"
     CDS             complement(<1..302)
                     /gene="traV"
                     /locus_tag="RN951_004433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system lipoprotein
                     TraV"
                     /protein_id="HDX2529309.1"
                     /translation="MKQISFFIPLLGTLLLSGCAGTSTEFECNATTSDTCMTMEQANE
                     KAKKLEQSSEAKPVAASLPRLAEGNFRTMPVQTVTATTPSGSRPAVTAHPEQKLLAP"
     gene            complement(299..550)
                     /gene="trbG"
                     /locus_tag="RN951_004434"
     CDS             complement(299..550)
                     /gene="trbG"
                     /locus_tag="RN951_004434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbG"
                     /protein_id="HDX2529310.1"
                     /translation="MNKLVSDGSVKKINYPVLYESGITPPLCEVSAPEPDAGGKRIVA
                     YVYKSSRSTVFENPDIVKTCTVRDLKKDFVNCDEKGEGQ"
     gene            complement(562..792)
                     /locus_tag="RN951_004435"
     CDS             complement(562..792)
                     /locus_tag="RN951_004435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001352845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbD"
                     /protein_id="HDX2529311.1"
                     /translation="MTEQTETTEIKMNMRNINVITALSVPGKTVSDDFMHAVLSNCAT
                     RIVLPAPEKFGSESLPDNFNMTAVGVMKNSEI"
     gene            complement(746..1336)
                     /locus_tag="RN951_004436"
     CDS             complement(746..1336)
                     /locus_tag="RN951_004436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraP"
                     /protein_id="HDX2529312.1"
                     /translation="MANNMSSRQACHAARYVVARVLRGLFWCLKYTVILPLATMALMA
                     LFVLWKDNTTPGKLLVKEINFVRQTAPAGQFPVSECWFSSSDSSGRSEIQDICHYRAA
                     DAADYVRETDRSLMQLVTALWATLALMYVSLAAITGKYPVRPGKMKCIRVVTADEHLK
                     EVYTEDASLPGKIRKCPVYLPDDRTNRNNGDKNEHA"
     gene            complement(1326..2753)
                     /locus_tag="RN951_004437"
     CDS             complement(1326..2753)
                     /locus_tag="RN951_004437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001553749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraB"
                     /protein_id="HDX2529313.1"
                     /translation="MASINTIVKRKQYLWLGIVVVGTASAIGGALYLSDVDMSGNGET
                     VAEQEPVPDMTGVVDTTFDDKVRQHATTEMQVTAAQMQKQYEEIRRELDVLNKQRGDD
                     QRRIEKLGQDNAALAEQVKALGANPVTATGEPVPQMPASPPGPEGEPQPGNTPVSFPP
                     QGSVAVPPPTAFYPGNGVTPPPQVTYQSVPVPNRIQRKVFTRNEGKQGPSLPYIPSGS
                     FAKAMLIEGADANASVTGNESTVPMQLRITGLVEMPNSKTYDATGCFVGLEAWGDVSS
                     ERAIVRTRNISCLKDGKTIDMPIKGHVSFRGKNGIKGEVVMRNGKILGWAWGAGFVDG
                     IGQGMERASQPAVGLGATAAYGAGDVLKMGIGGGASKAAQTLSDYYIKRAEQYHPVIP
                     IGAGNEVTVVFQDGFQLKTVEEMALERTQSRAEEDNPESPVPVPPSAESHLNGFNTDQ
                     MLKQLGNLNPQQFMSGSQGGGNDGK"
     gene            complement(2753..3457)
                     /gene="traK"
                     /locus_tag="RN951_004438"
     CDS             complement(2753..3457)
                     /gene="traK"
                     /locus_tag="RN951_004438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system secretin
                     TraK"
                     /protein_id="HDX2529314.1"
                     /translation="MFGSLFFSCSVMAANGTLAPTVVPMVNGGQASIAISNTSPNLFT
                     VPGDRIIAVNSLDGALTNNEQTASGGVVVATVNKKPFTFILETERGLNLSIQAVPREG
                     AGRTIQLVSDLRGTGEEAGAWETSTPYESLLVTISQAVRGGKLPAGWYQVPVTKETLQ
                     APAGLSSVADAVWTGNHLKMVRFAVENKTLSALNIRESDFWQPGTRAVMFSQPASQLL
                     AGARMDVYVIRDGEGN"
     gene            complement(3468..4034)
                     /gene="traE"
                     /locus_tag="RN951_004439"
     CDS             complement(3468..4034)
                     /gene="traE"
                     /locus_tag="RN951_004439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HDX2529315.1"
                     /translation="MEHGARLSTSRVMAIAFIFMSVLIVLSLSVNVIQGVNNYRLQNE
                     QRTAVTPMAFNVPFAVSQNSADASYLQQMALSFIALRLNVSSETVDASHQALLQYIRP
                     GAQNQMKVILAEEAKRIKNDNVNSAFFQTSVRVWPQYGRVEIRGVLKTWIGDSKPFTD
                     IKHYILILKRENGVTWLDNFGETDDEKK"
     gene            complement(4056..>4234)
                     /gene="traL"
                     /locus_tag="RN951_004440"
     CDS             complement(4056..>4234)
                     /gene="traL"
                     /locus_tag="RN951_004440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraL"
                     /protein_id="HDX2529316.1"
                     /translation="KYLFGIGAAVLVYFGIKKLKKGRGSSWLRDLIYWYMPTALLRGI
                     FHNVPDSCFRQWIK"
BASE COUNT          958 a         1199 c         1037 g         1040 t
ORIGIN      
        1 ggtgccagca gtttctgctc cggatgtgct gtcaccgcag gtctgctgcc ggacggagtg
       61 gtcgcggtga cggtctgcac cggcattgtc cggaagttcc cttcagccag gcgcggcagt
      121 gatgccgcaa ccggctttgc ttctgaggac tgctccagtt ttttggcctt ctcattggcc
      181 tgctccatcg tcatacaggt atcggatgtg gtggcgttac actcaaattc cgtactggtt
      241 ccggcacagc cggaaagtaa taaggtcccc agcagaggaa taaagaaaga aatctgtttc
      301 attgtccctc acctttctca tcgcagttca caaaatcctt cttcaaatcc ctgaccgtac
      361 aggtttttac aatgtcagga ttttcaaaaa ccgtactccg tgatgattta taaacatatg
      421 ccacaatgcg tttcccaccc gcatcaggtt ctggtgcact gacttcacat aacggaggtg
      481 ttattccgga ctcatacagc accggataat ttattttttt gacgctgcca tcagaaacca
      541 gcttattcat cgaagggttc cttatatttc tgaattcttc atcacaccga cagcagtcat
      601 attaaaattg tccggcaatg actcagaacc gaatttctcc ggtgcaggaa gtacgattct
      661 tgtggcgcag ttactgagaa cagcatgcat aaaatcatct gacacggttt tacccggcac
      721 agagagggct gtaataacat taatattacg catgttcatt tttatctccg ttgtttctgt
      781 ttgttctgtc atcaggaaga taaacagggc atttcctgat ttttcccggc agggaagcgt
      841 cttccgtata aacttccttc agatgttcat ctgcggttac cacccggata catttcattt
      901 ttcctggtcg caccggatat ttcccggtga tcgctgccag cgagacatac atcagtgcca
      961 gtgttgccca taatgcggtg accagttgca tcagtgaccg gtcagtctcc ctgacataat
     1021 ctgcagcatc agccgcgcgg taatggcaga tatcctgtat ttctgatctg cctgaagaat
     1081 cagaggaaga aaaccagcat tcactgaccg ggaactgtcc ggcaggtgct gtttgtctta
     1141 cgaagttaat ctccttaacc agtaatttcc ccggcgtggt gttgtccttc cataaaacaa
     1201 acagagccat cagggccatt gtggccagtg gcagaatgac ggtgtacttc agacaccaga
     1261 acagtcctcg cagaacccgg gcgacaacat accgggcggc atggcacgcc tgacgggacg
     1321 acatattatt tgccatcgtt gccccctccc tggctgccgg acataaactg ctgcggattc
     1381 aggttgccca gctgcttcag catctggtca gtattaaagc cgttaagatg actttcagcc
     1441 gatggcggaa caggaaccgg actttccgga ttgtcttctt ccgctctgct ctgcgtgcgt
     1501 tccagcgcca tctcttccac ggttttcagc tggaagccgt cctggaacac cacggtcact
     1561 tcgttgcccg caccaatcgg tatcaccggg tgatactgtt cggcacgttt gatgtagtag
     1621 tcactgagcg tctgtgcggc tttcgatgcg ccgccaccga tacccatttt caggacatca
     1681 ccagccccgt aagcggctgt ggcacccagc ccgacagccg gctgggaggc gcgctccatt
     1741 ccctgaccga taccgtcaac aaatcccgcg ccccatgccc agccgaggat tttgccgtta
     1801 cgcatcacca cttcgccctt gataccgttt ttaccccgga agctgacatg ccccttaatc
     1861 ggcatatcaa tagttttgcc gtccttcagg caactgatat tgcgggtgcg tacaatggca
     1921 cgctcactgg acacatcccc ccaggcttcc agacccacaa aacatcccgt tgcgtcatac
     1981 gtcttgctgt tcggcatttc caccaggccg gtgatacgca gctgcatcgg caccgtggat
     2041 tcattaccgg tgacagaggc attggcatcc gccccttcaa tcagcatggc tttcgcaaaa
     2101 cttcctgacg gaatgtacgg cagtgatggt ccctgttttc cctcattacg ggtaaacacc
     2161 ttacgctgta tccggttagg caccggcaca gactggtacg tcacctgtgg tggtggcgtg
     2221 acaccattcc cgggataaaa cgccgtcggc ggtggaacag caacgctgcc ctgcggcggg
     2281 aaggatacgg gggtgtttcc tggctgtggt tcgccttccg ggccgggcgg tgaggcaggc
     2341 atctgcggta caggctcacc ggtcgccgtg acgggattag cacccagggc ttttacctgc
     2401 tctgccaggg cggcattgtc ctgtcccaac ttttcaatac gacgctggtc atcaccgcgc
     2461 tgtttgttca gaacatccag ctcacgacgg atttcctcat actgcttctg catctgcgct
     2521 gccgtcacct gcatctcggt ggtggcatgc tgacgcacct tgtcatcaaa ggtcgtatcc
     2581 accacaccgg tcatatccgg cacaggctcc tgttcagcca cggtttcacc gttaccggac
     2641 atgtccacat cagacagata cagtgcccca ccaatcgcgg aggctgtacc gacaaccaca
     2701 atccccagcc acaggtactg cttgcgtttc acaatggtat tgatactggc catcagttgc
     2761 cctccccgtc acggatgaca tacacatcca tgcgcgcacc tgccagtaac tggctggcag
     2821 gctggctgaa catcacggca cgggttcccg gctgccagaa gtcactttcc cggatattca
     2881 gggcagacag cgttttattt tccacggcaa agcggaccat cttcaggtga ttccccgtcc
     2941 atacggcatc tgccactgaa gacagccccg ccggggcctg cagggtttcc tttgtcactg
     3001 ggacctgata ccagcctgcg ggtaattttc cgccacggac ggcctggctg atggtcacaa
     3061 gcagggattc gtaaggcgtg gacgtttccc acgcaccggc ttcttctccg gttccgcgca
     3121 ggtcactgac cagctgaatg gtacgccccg cgccttcacg gggaacggcc tgaatggaaa
     3181 gattcagacc acgttctgtt tccagaatga acgtaaaggg ctttttgttg acggtggcaa
     3241 ccaccacacc gccggaggcg gtctgctcat tattggtcag ggcaccatcc agactgttca
     3301 cggcgataat ccggtcaccg ggaacggtaa acagattcgg gctggtattg ctgatggcaa
     3361 tactggcctg accaccgttc accattggca ccacggtggg ggccagcgta ccgtttgcgg
     3421 ccatcacgct gcaggaaaaa aacaggctgc cgaatattat tgccgtatta ttttttctca
     3481 tcgtctgttt ccccgaaatt atccagccag gtcaccccgt tttcccgctt cagaataagg
     3541 atgtaatgtt tgatatcagt gaaaggtttt gaatcaccaa tccaggtttt aagcacacct
     3601 cgaatttcca cacggccata ctgaggccag acacgaacac tggtctggaa aaaggctgag
     3661 ttcacgttat cgtttttaat acgcttcgct tcttcagcca gaataacttt catctggttc
     3721 tgtgcgcccg ggcggatata ttgcagaagc gcctgatgtg aggcatcgac ggtttctgat
     3781 gaaacattca gacggagggc aataaatgac agcgccatct gctgtaaata agaggcgtcg
     3841 gcactgttct gtgacacggc aaaggggaca ttaaatgcca ttggcgtcac ggcagtgcgt
     3901 tgctcattct gaagacggta gttattcacc ccctgaatga cgttaacaga gaggctgaga
     3961 acaataagca ctgacataaa tataaaggcg atggccatta cacgactggt acttaaacgg
     4021 gcaccgtgtt ccatataaca atcctggtat cagttctatt taatccactg ccggaaacac
     4081 gaatcgggaa cattatgaaa aataccgcgc agcagggctg ttggcatata ccagtaaatc
     4141 aggtcacgta accaggaact gccccgccct tttttcagtt ttttaatccc gaaataaacc
     4201 agaaccgctg caccaatacc gaacagatat ttcg
//
LOCUS       DAPOAV010000193         4195 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.197, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000193 DAPOAV010000000
VERSION     DAPOAV010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4195
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.197"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(1..706)
                     /locus_tag="RN951_004441"
                     /pseudo
     CDS             complement(1..706)
                     /locus_tag="RN951_004441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611435.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1121..1270)
                     /locus_tag="RN951_004442"
     CDS             complement(1121..1270)
                     /locus_tag="RN951_004442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017880354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529317.1"
                     /translation="MPSEHDEQLDSTDTQLPGEYDLFDLMAQVTEENLHALVDFGPPV
                     GREAL"
     gene            2355..2672
                     /locus_tag="RN951_004443"
     CDS             2355..2672
                     /locus_tag="RN951_004443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529318.1"
                     /translation="MKKIFILSAALIMAGCATKQYPQAVNVTGPESSAMDCKAVALEI
                     AKTRSVQQEIEETGEFDGRTVLGFLGDFGIGNGMAKGEARKKAANRLNQLEALKAAKC
                     ADQ"
     gene            3856..3990
                     /locus_tag="RN951_004444"
     CDS             3856..3990
                     /locus_tag="RN951_004444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDX2529319.1"
                     /translation="MHEPPVQSDRCVLSGNYRLESNPERHAKTPLAAAIGKQDVREMQ
                     "
BASE COUNT         1088 a         1074 c         1043 g          990 t
ORIGIN      
        1 ttcgatggcg gtacagcagg ttttcgctca agcaacagcg cattctggcg catgatccgg
       61 taaacacgtt tggcattgat cgcaggcata ccatcaagtt ctgcctgtct gcgaagcagc
      121 gcccataccc gacgataacc atacgtgggc agctctccga taacatggtg tatacggaga
      181 agcacatccg tatcatcagt gtgacgactg cggcggccat ccatccagtc atcggttcgt
      241 ctgagaatga cgtgcaactg cgcacgcgac acccggagac aacggctgac taagcttact
      301 ccccatcccc gggcaataag ggcgcgtgcg ctatccactt ttttgcccgt ccatattcaa
      361 cggcttcttt gaggagttca ttttccatcg ttttcttgcc gagcaggcgc tggagttctt
      421 taatctgctt catggcggca gcaagttcag aggcaggaac aacctgttct ccggcggcga
      481 cagcagtaag acttccttcc tggtattgct tacgccagag aaataactgg ctggctgcta
      541 caccatgttg ccgggcaacg agggagaccg tcatccccgg ttcaaagctc tgctgaacaa
      601 ttgcgatctt ttcctgtgtg gtacgccgtc tgcgtttctc cggccctaag acatcaatca
      661 tctgttctcc aatgactagt ctaaaaacta gtattaagac tatcacttat ttaagtgata
      721 ctggttgtct ggagattcag ggggccagtc tagtcttaca tttgtctcat aatagtccaa
      781 aataagagta aaacgcaaaa aatgtcttac aattgtctta tttttgtcct ttccggttca
      841 tggatacatg aaccgcctga tgtggaacgc tttttatcga tctcatgcgc tgccaaagat
      901 agattcattc tttaaaagtc aggttacatt atcccttaaa tggtcataca ccatacgcaa
      961 ccgcgatttt catcgcaatt gcatgaatta aaagataaaa actgaagtcc ccgtttattt
     1021 atgtaatacg caacgtatta caaccacctg taattacatg aaaataaaga aataagatgt
     1081 aataccggcg tattaccacg tacgcgggta agcgaaaaag ctataacgct tcccggccga
     1141 caggcggccc aaaatccacc agggcatgca ggttctcttc agtaacctgc gccattaaat
     1201 caaaaaggtc atattcgccg ggaagctgcg tatcagtcga atccagttgt tcatcatgtt
     1261 cagatggcat ggggtgatat ccagtagctg agaggttgtt agagggtttc ggggcgcagc
     1321 cctgaaccag tcacgtagcg ctagcggagt gtatactggc ttactatgtt ggcactgatg
     1381 agggagtcag tgaagtgctt catgtggcag gacaaaaaag gcggcaccgg tgcgtcagca
     1441 gaatatgtga tacaggatat attccgcttc ctcgctcact gactcgctac gctcggtcgt
     1501 tcgactgcgg cgagcggaaa tggcttacga acggggcgga gatgtcctgg aagatgccag
     1561 ggaaatactt aacagggaag cgatagggcc gcggcaaagc cgtttttcca taggctccgc
     1621 ccccctgaca agcatcacga aatctgacgc tcaaatcagt ggtggcgaaa cccgacagga
     1681 ctataaagat accaggcgtt tccccctggc ggctccctcg tgcgctctcc tgttcctgcc
     1741 tttcggttta ccggtgtcat tccgctgtta tggccgcgtt tgtctcattc cacgcctgac
     1801 actcagttcc gggaaggcag ttcgctccaa gctggactgt atgcacgaac cccccgttca
     1861 gtccgactgc tgcgccttat ccggtaacta tcgtcttgag tccaacccgg aaagacacga
     1921 caaagcgcca ctggcagcag ccactggtaa caggattagc agagcgagtt aatgtaggtg
     1981 gtgctataga gttcttgaag tggtggccta actacggcta cactagaagg acagtatttg
     2041 gtatctgcgc tctgctgaag ccagttacca ggttaagcag ttccccaact gacttaacct
     2101 tcgaaaaacc acctccccag gtggtttttt cgttttcaga gcaagagatt acgcgtagaa
     2161 aaaaaggaac tcaagaagat cctttctatg ctcaaccacc gcatggccca tagccgcgct
     2221 ggccgttgcc ggtcagctcc agaatcctcg accaatatgg aaccttgccc ctcccaaaat
     2281 tcaactaaaa aaccctcatt tcctgccgat aaaatgggta tctcttaact atgcctaaat
     2341 aaataaggat aattttgaaa aaaatattca tcctatcggc agcgctgatc atggcaggat
     2401 gcgcaacaaa gcaatatcca caggccgtga acgtcaccgg tccagaatct tccgcaatgg
     2461 attgcaaagc ggtagctctg gaaatcgcca aaacgcgcag tgtacaacaa gaaattgagg
     2521 aaaccggcga atttgacggg cgcaccgtat taggtttcct gggtgatttt gggataggaa
     2581 atggcatggc aaaaggcgaa gcccgcaaaa aagcagctaa ccggctaaat cagctggaag
     2641 ccctgaaggc tgcaaagtgt gcagatcaat aaggtacaaa aaagccctcg gggctttttt
     2701 tgtacctgcc aatcagctga atttaccata acatccgttg cgtgcaccat ctcagacgcc
     2761 ctcagggcat ttctgcgccc tcctgcctat ttccggcatc tttccctgtc catatcgtga
     2821 aaaaacgcgc ctgatgattt cttcgcgtct gcatggctat gcacacgaac gcatggacgt
     2881 cattttagcg gctaaaatcc ggcgagcgcc ctgaaagcca ccacgaaccc caccgataac
     2941 ggtgaaaggg tgcgcagttt actgtgcgac cgtgaggcgt tggccaggcc gtcaggcatg
     3001 gcaggattta ttgctaaggg ggtcggattt aacctggatt aatcagcaca cagtgatgaa
     3061 cgggattcgg aaggggcacc cttgcggcgc ggcgatgtat acatcgctaa cgtgccttgg
     3121 tcatttattg caagaaggga gaggtagcat tttgatagca aaaaagtagc aaaaggatag
     3181 caaccgaaag accagaagac tctggagata gcaaaaaagt agcaaaatgg tagcaaaaag
     3241 atagcaaaca tgcgggagct aaccaggagt ctttagcggg ccggcggtac tccaaaaaca
     3301 cattttgtcc cgctgttttg tgaataaccc agcatagctg tgggcacaaa acatttcctg
     3361 tccgctgctt taacctttgt aatccaggaa cgtcaggtga cgtcactttg cggcgttagc
     3421 cctatcctgc atcctatgaa aaaatgcagt tacggagtgt aaggtgccgg acgtgaggcc
     3481 gaagatattc cgcttcctcg ctcactgact cgctacgctc ggtcgttcgg ctgcggcgag
     3541 cggacggaga atattcacaa aggcatatgg cgatgaagac gagataaagc gagggaggaa
     3601 aggccgcggc gctgccggtt ttccataggc tccgcccccc tgacaagcat cacagaatct
     3661 gacgctcaaa tcagtggtgg cgaaacccga caggactata aagatcccag gcgtttcccc
     3721 ctggtagctc cctcgtgcgc tctcctgttc ctgcctttcg gtttaccggt gtcattccgc
     3781 tgttatggcc gcgtttgtct cattccacgc ctgacactca gttccgggta ggcagttcgc
     3841 tccaagctgg actgtatgca cgaacccccc gttcagtccg accgctgcgt cttgtccggt
     3901 aactatcgtc ttgagtccaa tccggaaaga cacgcaaaaa cgccactggc agcggccatt
     3961 ggtaaacagg atgtgcgaga gatgcagtaa gagttcttga agtgatggcc tgagtgcggc
     4021 tacactgaaa ggacagattt ggtgacatgt ctcgcacaag actgttaccg cggttagaaa
     4081 atctgccagg attagctaac cttcgaaaaa ccacctgcca gggtggtttt ttcgtttaca
     4141 gagcaagaga ttacgacgca acagaaagga tctcaagaag ttccttgctg tattg
//
LOCUS       DAPOAV010000194         4074 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.198, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000194 DAPOAV010000000
VERSION     DAPOAV010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4074
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.198"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            163..378
                     /gene="bdm"
                     /locus_tag="RN951_004445"
     CDS             163..378
                     /gene="bdm"
                     /locus_tag="RN951_004445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415998.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-dependent modulation protein"
                     /protein_id="HDX2529320.1"
                     /translation="MFTYYQAENSTAEPALVNAIEQGLRAQHGVVTEDDILMELTKWV
                     EASDNDILSDIYQQTINYVVSGQHPTL"
     gene            480..617
                     /gene="sra"
                     /locus_tag="RN951_004446"
     CDS             480..617
                     /gene="sra"
                     /locus_tag="RN951_004446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary-phase-induced ribosome-associated
                     protein"
                     /protein_id="HDX2529321.1"
                     /translation="MKSNRQARHILGLDHKISNQRKIVTEGDKSSVVNNPTGRKRPAE
                     K"
     gene            774..2471
                     /gene="maeA"
                     /locus_tag="RN951_004447"
     CDS             774..2471
                     /gene="maeA"
                     /locus_tag="RN951_004447"
                     /EC_number="1.1.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415996.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HDX2529322.1"
                     /translation="MEPKTKKQRSLYIPYAGPVLLEFPLLNKGSAFSMEERRNFNLLG
                     LLPEVVETIEEQAERAWIQYQGFKTEIDKHIYLRNIQDTNETLFYRLVNNHLDEMMPV
                     IYTPTVGAACERFSEIYRRSRGVFISYQNRHNMDDILQNVPNHNIKVIVVTDGERILG
                     LGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRNPRI
                     TDDEYYEFVDEFIQAVKQRWPDVLLQFEDFAQKNAMPLLNRYRNEICSFNDDIQGTAA
                     VTVGTLIAASRAAGGQLSEKKIVFLGAGSAGCGIAEMIISQTQREGLSEEAARQKVFM
                     VDRFGLLTDKMPNLLPFQTKLVQKRENLSDWDTDSDVLSLLDVVRNVKPDILIGVSGQ
                     TGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIAWTEGNALVATGSPFNPVV
                     WKDKIYPIAQCNNAFIFPGIGLGVIASGASRITDEMLMSASETLAQYSPLVLNGEGMV
                     LPELKDIQKVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDNFWQAEYRDYRRTSI"
     gene            2605..3615
                     /gene="adhP"
                     /locus_tag="RN951_004448"
     CDS             2605..3615
                     /gene="adhP"
                     /locus_tag="RN951_004448"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415995.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HDX2529323.1"
                     /translation="MKAAVVTKDHHVDVTYKTLRSLKHGEALLKMECCGVCHTDLHVK
                     NGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETL
                     CRSVKNAGYSVDGGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTYKAVKLSKIR
                     PGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINSHTEDA
                     AKIVQEKTGGAHAAVVTAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDIPRLVLDG
                     IEVVGSLVGTRQDLTEAFQFAAEGKVVPKVALRPLADINTIFTEMEEGKIRGRMVIDF
                     RH"
     gene            3761..4045
                     /locus_tag="RN951_004449"
     CDS             3761..4045
                     /locus_tag="RN951_004449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415994.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HigA family addiction module antidote protein"
                     /protein_id="HDX2529324.1"
                     /translation="MKMANHPRPGDIIQESLDELNVSLREFARAMEIAPSTASRLLTG
                     KAALTPEMAIKLSVVIGSSPQMWLNLQNAWSLAEAEKTVDVSRLRRLVTQ"
BASE COUNT         1090 a          977 c         1059 g          948 t
ORIGIN      
        1 taccaatcac aatccctatg aatatcatgg tgttaaaata taaaaatcat caaccaggac
       61 taatcttaac aacgaagcgg caaatatttg ccatgctgaa tgtgctttat aaatctgcga
      121 tccgtagcag acaccataaa tacacagaca cggagaatca ctatgtttac ttattatcag
      181 gcagaaaatt caacagcaga acccgctctg gttaatgcca ttgagcaagg ccttcgggca
      241 cagcatggtg ttgtcactga agatgacatt ctcatggagc tgaccaaatg ggttgaagct
      301 tctgataacg acatcctcag tgatatctac cagcaaacga tcaattatgt ggtcagtggc
      361 cagcacccta cgctttaagg tgctatgctt gatcggcaac ctaatttagg ggtttagcac
      421 gtgtttcttc gctacggcga tgttgtcctt aaaactagct acaggattga ggagttaaaa
      481 tgaaatcgaa ccgtcaggca cgtcatattc ttggactgga ccataaaatt tctaaccagc
      541 gcaaaatagt taccgaaggt gacaaatcca gcgtagtaaa taacccaacc ggcagaaaac
      601 gccccgctga aaagtaattc ataaccatca gtcctcaatg acgattaaac accattgcct
      661 gcgcaatggt gtttttgttt ttatctgctt tatacttgag gccgacgccc tggcggtaaa
      721 gcaaagacga taaaagcccc ccagggatgg atattcaaaa aagagtgagt gacatggaac
      781 caaaaacaaa aaaacagcgt tcgctttata tcccttacgc tggccctgta ctgctggaat
      841 ttccgttgtt gaataaaggc agtgccttca gcatggaaga acgccgtaac ttcaacctgc
      901 tggggttact gccggaagtg gtcgaaacca tcgaagaaca agcggaacga gcatggatcc
      961 agtatcaggg attcaaaacc gaaatcgaca aacacatcta cctgcgtaac atccaggaca
     1021 ctaacgaaac cctcttctac cgtctggtaa acaatcatct tgatgagatg atgcctgtta
     1081 tttatacccc aaccgtcggc gcagcctgtg agcgtttttc tgagatctac cgccgttcac
     1141 gcggcgtgtt tatctcttac cagaaccggc acaatatgga cgatattctg caaaacgtgc
     1201 cgaaccataa tattaaagtg attgtggtga ctgacggtga acgcattctg gggcttggtg
     1261 accagggcat cggcgggatg ggcattccga tcggtaaact gtcgctctat accgcctgtg
     1321 gcggcatcag cccggcgtat acccttccgg tggtgctgga tgtcggaacg aacaaccaac
     1381 agctgcttaa cgatccgctg tatatgggct ggcgtaatcc gcgtatcact gacgacgaat
     1441 actatgaatt cgttgatgaa tttatccagg ctgtgaaaca acgctggcca gacgtgctgt
     1501 tgcagtttga agactttgct caaaaaaatg cgatgccgtt acttaaccgc tatcgcaatg
     1561 aaatttgttc ttttaacgat gacattcagg gcactgcggc ggtaacagtc ggcacactga
     1621 tcgcagcaag ccgcgcggca ggtggtcagt taagcgagaa aaaaatcgtc ttccttggcg
     1681 caggttcagc gggatgcggc attgccgaaa tgatcatctc ccagacccag cgcgaaggat
     1741 taagcgagga agcggcgcgg cagaaagtct ttatggtcga tcgctttggc ttgctgactg
     1801 acaagatgcc gaacctgctg cctttccaga ccaaactggt gcagaagcgc gaaaacctca
     1861 gtgactggga taccgacagc gatgtgctgt cactgctgga tgtggtgcgc aatgtaaaac
     1921 cagatattct gattggcgtc tcaggacaga ccgggctgtt tacggaagag atcatccgtg
     1981 agatgcataa acactgtccg cgtccgatcg tgatgccgct gtctaacccg acgtcacgcg
     2041 tggaagccac accgcaggac attatcgcct ggaccgaagg taacgcgctg gtcgccacgg
     2101 gcagcccgtt taatccagtg gtatggaaag ataaaatcta ccctatcgcc cagtgtaaca
     2161 acgcctttat tttcccgggc atcggcctgg gtgttattgc ttccggcgcg tcacgtatca
     2221 ccgatgagat gctgatgtcg gcaagtgaaa cgctggcgca gtattcacca ttggtgctga
     2281 acggcgaagg tatggtactg ccggaactga aagatattca gaaagtctcc cgcgcaattg
     2341 cgtttgcggt tggcaaaatg gcgcagcagc aaggcgtggc ggtgaaaacc tctgccgaag
     2401 ccctgcaaca ggccattgac gataatttct ggcaagccga ataccgcgac taccgccgta
     2461 cctccatcta agcctgcgcc cggtagtgaa ggctaccggg ctatttccct ctcccttttt
     2521 cagatctcat ccatactggg tagtggcgaa taaatctcat ttgcctcacc tgctatgcag
     2581 aacatcatcc gaaaaggagg aactatgaag gctgcagttg ttacgaagga tcatcatgtt
     2641 gacgttacgt ataaaacact gcgctcactg aaacatggcg aagccctgct gaaaatggag
     2701 tgttgtggtg tatgtcatac cgatcttcat gttaagaatg gcgattttgg tgacaaaacc
     2761 ggcgtaattc tgggccatga aggcatcggt gtggtggcag aagtgggtcc aggtgtcacc
     2821 tcattaaaac caggcgatcg tgccagcgtg gcgtggttct acgaaggatg cggtcattgc
     2881 gaatactgta acagtggtaa cgaaacgctc tgccgttcag ttaaaaatgc cggatacagc
     2941 gttgatggcg ggatggcgga agagtgcatc gtggtcgccg attacgcggt aaaagtgcca
     3001 gatggtctgg actcggcggc ggccagcagc attacctgtg cgggagtcac cacctacaaa
     3061 gccgttaagc tgtcaaaaat tcgtccaggg cagtggattg ctatctacgg tcttggcggt
     3121 ctgggtaacc tcgccctgca atacgcgaag aatgtcttta acgccaaagt gatcgccatt
     3181 gatgtcaatg atgagcagtt aaaactggca accgaaatgg gcgcagattt agcgattaac
     3241 tcacacaccg aagacgccgc caaaattgtg caggagaaaa ctggtggcgc tcacgctgcg
     3301 gtggtaacag cggtagctaa agctgcgttt aactcggcag ttgatgctgt ccgtgcaggc
     3361 ggtcgtgttg tggctgtcgg tctaccgccg gagtctatga gcctggatat cccacgtctt
     3421 gtgctggatg gtattgaagt ggtcggttcg ctggtcggca cgcgccagga tttaactgaa
     3481 gccttccagt ttgccgccga aggtaaagtg gtgccgaaag tcgccctgcg tccgttagcg
     3541 gacatcaaca ccatctttac tgagatggaa gaaggcaaaa tccgtggccg catggtgatt
     3601 gatttccgtc actaagaggc ctttgctgcg actgccatgt tcgggtcgca gcatcgcaca
     3661 ctctccaaca tgaaatggct aaatggatta ttgttgcgta ggaaggaaca ataatgatag
     3721 tgttcccagt gaaggaacgc tactgagagt aaagacacta atgaaaatgg ccaatcatcc
     3781 ccgcccgggg gacattattc aggaatcact ggacgaactt aatgtcagcc tgcgcgagtt
     3841 tgccagagca atggaaattg ctccctcaac ggcaagccga ttgctgacag gaaaagcagc
     3901 tttgacgcca gaaatggcga ttaaactttc cgtggtgatc ggcagttcgc cgcaaatgtg
     3961 gctgaatctg caaaacgcct ggagtctggc agaggcagaa aaaacagtgg atgtgtcgcg
     4021 attacgccgt ctggttacgc aataaaaaaa tggcacttta taaagcgcca ttta
//
LOCUS       DAPOAV010000195         4071 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.199, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000195 DAPOAV010000000
VERSION     DAPOAV010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4071
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.199"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            75..791
                     /gene="nanC"
                     /locus_tag="RN951_004450"
     CDS             75..791
                     /gene="nanC"
                     /locus_tag="RN951_004450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313297.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminic acid outer membrane channel
                     NanC"
                     /protein_id="HDX2529325.1"
                     /translation="MKKAKILSGVLLLCFSSPLISQAATLDVRGGYRSGSHAYETRLK
                     VSEGWQNGWWASMESNTWNTIHDNKKENAALNDVQVEVNYAIKLDDQWTVRPGMLTHF
                     SSNGTRYGPYVKLSWDATKDLNFGIRYRYDWKAYRQQDLSGDMSRDNVHRWDGYVTYH
                     INSDFTFAWQTTLYSKQNDYRYANHKKWATENAFVLQYHMTPDITPYIEYDYLDRQGV
                     YNGRDNLSENSYRIGVSFKL"
     gene            811..1917
                     /gene="nanM"
                     /locus_tag="RN951_004451"
     CDS             811..1917
                     /gene="nanM"
                     /locus_tag="RN951_004451"
                     /EC_number="5.1.3.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418730.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate epimerase"
                     /protein_id="HDX2529326.1"
                     /translation="MNKTITALAILMASFAANASVLPETPVPFKSGTGAIDNDTVYIG
                     LGSAGTAWYKLDTQAKDKKWTALAAFPGGPRDQATSAFIDGNLYVFGGIGKNSEGLTQ
                     VFNDVHKYNPKTNSWVKLISHAPMGMAGHVTFVHNGKAYVTGGVNQNIFNGYFEDLNE
                     AGKDSTAIDKINAHYFDKKAEDYFFNKFLLSFDPSTQQWSYAGESPWYGTAGAAVVNK
                     GDKTWLINGEAKPGLRTDAVFELDFTGNNLKWNKLAPVSSPDGVAGGFAGISNDSLIF
                     AGGAGFKGSRENYQNGKNYAHEGLKKSYSADIHLWHNGKWDKSGELSQGRAYGVSLPW
                     NNSLLIIGGETAGGKAVTDSVLISVKDNKVTVQN"
     gene            1981..2961
                     /locus_tag="RN951_004452"
     CDS             1981..2961
                     /locus_tag="RN951_004452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HDX2529327.1"
                     /translation="MNAIISPDYYYVLTVAGQSNAMAYGEGLPLPDREDAPHPRIKQL
                     ARFAHTHPGGPSCHFNDIIPLTHCPHDVQDMQGYHHPLATNHQTQYGTVGQALHIARK
                     LLPFIPDNAGVLIVPCCRGGSAFIAGSEGTYSERHGASHDACRWGTDTPLYQDLVSRT
                     RAALAKNPQNKFLGVCWMQGEFDLMTSDYASHTQHFNHMVEAFRRDLKKYHSQLNNIT
                     DAPWFCGDTTWYWKENFPHAYEVIYGNYQNNVLANIIFVDFQQQGERGLTNAPDEDPD
                     DLSTGYYGSAYRSPENWTTALRSSHFSAAARRGIISDRFVEAILQFWRER"
     gene            complement(2969..3091)
                     /locus_tag="RN951_004453"
     CDS             complement(2969..3091)
                     /locus_tag="RN951_004453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012139841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDX2529328.1"
                     /translation="MISFVFLLPVCPNCHAMLHRRKPPFTPEELKALMDANKSN"
     gene            3173..4045
                     /locus_tag="RN951_004454"
     CDS             3173..4045
                     /locus_tag="RN951_004454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDX2529329.1"
                     /translation="MASSKSLQQAIANIKIWHKGEQRAPHKPLLLLYVLAGYLHGHPR
                     LFDYGSEIYEPLHSLLERFGPQRSQYRPDMPFWRLQGDGFWQLHNAERCSTAGSSRQP
                     PVKELNEYHVAGGFDEQHYALVTGNKKLINTLAQQILEAHFTESIQEEIADELGFDLQ
                     QIRKQRDPLFRKNVLRAYNYQCAICGFNMRHDDTTVALEAAHIKWKQHGGPCEIPNGL
                     ALCAIHHKAFDKGSIGLDENMRVLVSDAVNGGGIVERLFWDFDGKTIALPQVRKNYPY
                     EVFVEWHRNEVFRG"
BASE COUNT         1181 a          874 c          979 g         1037 t
ORIGIN      
        1 attacacaac ataaatgcta attgtttatg cgggctttgt attgctttct gtatcctaca
       61 aatgagtgaa atttatgaaa aaggctaaaa tactttctgg cgtattatta ctgtgctttt
      121 cgtcaccatt aatttctcag gctgcgacac tggacgtacg tggtggatat cgtagtggaa
      181 gccacgccta tgagactcga ctcaaagtca gtgagggatg gcaaaatgga tggtgggcaa
      241 gcatggaaag taatacctgg aataccattc atgataataa aaaggaaaat gccgcactca
      301 atgatgttca ggttgaagtt aattacgcga ttaaacttga tgatcaatgg acggtgcgcc
      361 cgggaatgtt aacgcatttt agcagcaacg gcacacgcta cggaccctac gtaaaactgt
      421 cctgggacgc gacaaaagat cttaattttg gcattcgcta tcgttacgac tggaaagctt
      481 accgacaaca agacttatcc ggtgatatgt ctcgtgataa cgttcatcgt tgggatggat
      541 atgtcactta ccatattaat agtgatttca ccttcgcatg gcaaacgacg ctatacagca
      601 aacagaacga ttatcgctat gcaaaccata agaaatgggc gacggaaaat gcatttgttc
      661 tacaatacca tatgacgccc gatattacgc catacataga atatgactac ctggaccgtc
      721 agggtgttta caacggcaga gataatttat cggaaaacag ttatcgcatt ggtgtgtcat
      781 ttaaactgta gtagacagga gacagtcaca atgaataaaa caataacggc gcttgctatc
      841 ctaatggctt catttgccgc aaacgcgtct gtattaccgg aaactcctgt accatttaaa
      901 agtggtaccg gagcaattga taacgacact gtctacattg gtttaggtag cgcaggtacg
      961 gcatggtaca agctggatac acaggccaaa gataaaaaat ggacagcgtt agctgcattc
     1021 cctggtggac caagagatca agcaacctcg gcatttattg atggcaatct gtatgtgttt
     1081 ggcggcattg gcaaaaacag cgagggcttg actcaggtat ttaatgacgt acacaaatac
     1141 aaccccaaaa ccaatagctg ggttaaattg atatcgcacg caccgatggg catggcgggc
     1201 catgtgactt ttgtacacaa cggcaaggct tatgttactg gcggtgttaa ccagaatatc
     1261 ttcaatggct attttgaaga tctcaacgaa gctggaaaag attcaaccgc tatagataaa
     1321 atcaatgcac actattttga caaaaaagca gaagattatt tctttaataa gtttctgttg
     1381 tcttttgatc cctctacaca gcaatggagt tacgctggcg aatctccctg gtacgggacg
     1441 gctggtgcgg cggttgtgaa taaaggtgat aaaacctggc ttattaatgg cgaagccaaa
     1501 cccggattgc gaacggatgc cgtatttgaa cttgatttca ccggtaataa tttaaaatgg
     1561 aataagcttg ctcccgtctc atcaccagat ggcgtcgctg gcggttttgc ggggataagc
     1621 aatgattctc ttatatttgc cggaggggcc ggattcaaag gttcacgaga aaattaccag
     1681 aacggtaaga actatgcgca tgaaggcctg aaaaaatcat atagcgctga tattcatctt
     1741 tggcataacg ggaaatggga taaatcgggt gaattatcgc aaggtcgggc ctacggagta
     1801 tcattgccct ggaataatag tctattaatt attggcggtg aaactgcagg cggcaaagcg
     1861 gtgacggatt cagttttgat ctctgtgaag gataataaag ttacagtaca aaactaacgc
     1921 ttcagggccc cagtaaaggg ccctgctatc aatttgtcat ttcaattacg cgaaatttat
     1981 atgaacgcaa taatatcgcc tgattattac tatgttctta ccgttgctgg tcagtctaat
     2041 gccatggcgt atggcgaagg actgccatta ccggacaggg aagatgcgcc tcatcccaga
     2101 attaaacaat tagcgagatt tgcgcatacg catcccggag gcccgtcatg tcactttaac
     2161 gacattattc cactgactca ctgcccacac gatgttcagg atatgcaggg ttatcaccat
     2221 cctctggcaa cgaatcatca aacacagtac ggcaccgttg gccaggcact gcatattgca
     2281 cggaaattac tgcccttcat tcctgataat gcaggggttc tcatcgttcc atgttgtcgt
     2341 ggcggctcgg cttttatcgc aggcagcgaa gggacatatt cagaacggca cggagccagc
     2401 catgatgctt gtcgttgggg aacggatact ccgctatacc aggatttagt cagcagaacg
     2461 cgagccgcac tggcaaaaaa tccgcagaac aaattcctcg gtgtatgctg gatgcaaggc
     2521 gaatttgact taatgaccag tgactacgcg tcacacactc aacactttaa tcatatggtt
     2581 gaagcctttc gtagggatct aaaaaaatac cattctcagc ttaataatat tactgacgcg
     2641 ccgtggtttt gcggcgatac cacctggtac tggaaagaaa atttccctca tgcgtatgaa
     2701 gttatttatg gcaattatca aaataatgtt ttagccaata ttattttcgt cgacttccag
     2761 caacaaggtg aaagaggact gacgaacgcg cctgatgaag atccggacga tttaagcacg
     2821 ggatattacg gttcagcgta ccggtcaccg gagaactgga cgacggcact gcgaagcagt
     2881 catttcagcg cggcagcccg tcgggggatt atttctgaca ggtttgtaga agcaatttta
     2941 cagttttggc gcgaaaggtg agcgttcatt aatttgattt attcgcatcc atcaacgctt
     3001 ttaactcctc cggcgtaaac ggtggtttgc gtcggtgcaa catcgcatgg caattagggc
     3061 acacaggcag caaaaaaaca aatgagatca aagtaatata tcttcacttg caggcttgaa
     3121 cagcagaaaa tttgcgagca tgattgcaat tatttcactg cctgggatat caatggcttc
     3181 cagtaagtcg ctacagcagg caattgccaa tataaaaatc tggcacaagg gtgaacagcg
     3241 cgcgccgcat aagccattgt tattgctata cgtattagcg ggatacctgc atggacatcc
     3301 gcgccttttc gattatggct cggaaatcta cgaacctctg cacagtttac tggaacgttt
     3361 tgggccacag cgttcacagt accgacctga tatgccgttc tggcgattac aaggcgacgg
     3421 attctggcaa ttacacaatg ccgagcgttg ctcaacagca gggagcagcc gacaaccgcc
     3481 agtgaaggaa ctgaacgaat accacgttgc aggcggtttc gatgaacagc actacgccct
     3541 ggtaaccggc aataaaaaac tcatcaatac tctggcgcaa cagatactcg aagcgcactt
     3601 caccgagagt attcaggaag aaatcgctga cgagctgggt tttgatctcc agcaaatccg
     3661 taaacagcgc gacccgttat ttcgcaaaaa tgtattacgc gcttataact accagtgcgc
     3721 aatatgtggc tttaatatgc gccacgatga caccaccgtc gcgctggaag cggcgcatat
     3781 aaaatggaaa cagcacggcg gtccttgtga aattcctaat ggcctggcgc tttgcgcaat
     3841 tcaccataaa gcctttgata aaggatcgat tggcctggat gaaaatatgc gggtactggt
     3901 atcagatgcg gtaaacggcg gagggatcgt tgagagatta ttctgggatt ttgacgggaa
     3961 aactattgcg ttgccgcagg tgcgtaaaaa ttacccttat gaggtgtttg tagagtggca
     4021 tcggaatgag gtttttaggg ggtgaggtag gctatcttgt gcatataaat a
//
LOCUS       DAPOAV010000196         4069 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.200, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000196 DAPOAV010000000
VERSION     DAPOAV010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4069
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.200"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(53..1450)
                     /gene="ccp"
                     /locus_tag="RN951_004455"
     CDS             complement(53..1450)
                     /gene="ccp"
                     /locus_tag="RN951_004455"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c peroxidase"
                     /protein_id="HDX2529330.1"
                     /translation="MKMVSRITAIGLAGVAICYLGLSGYVWYHDNKRSKQADVQASAV
                     SENNKVLGFLREKGCDYCHTPSAELPAYYYIPGAKQLMDYDIKLGYKSFNLEAVRAAL
                     LADKPVSQSDLNKIEWVMQYETMPPTRYTALHWAGKVSDEERAEILAWIAKQRAEYYA
                     SNDTAPEHRNEPVQPIPQKLPTDAQKVALGFALYHDPRLSADSTISCAHCHALNAGGV
                     DGRKTSIGVGGAVGPINAPTVFNSVFNVEQFWDGRAATLQDQAGGPPLNPIEMASKSW
                     DEIIAKLEKDPQLKAQFLEVYPQGFSGENITDAIAEFEKTLITPDSPFDKWLRGDENA
                     LTAQQKKGYQLFKDNKCATCHGGIILGGRSFEPLGLKKDFNFGEITAADIGRMNVTKE
                     ERDKLRQKVPGLRNVALTAPYFHRGDVPTLDGAVKLMLRYQVGKELPQEDVDDIVAFL
                     HSLNGVYTPYMQDKQ"
     gene            1854..3503
                     /locus_tag="RN951_004456"
     CDS             1854..3503
                     /locus_tag="RN951_004456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase"
                     /protein_id="HDX2529331.1"
                     /translation="MLNQKIQNPNPDELMIEVDLCYELDPYELKLDEMIEAEPEPEMI
                     EGLPASDALTPADRYLELFEHVQSAKIFPDSKTFPDCAPKMDPLDILIRYRKVRRHRD
                     FDLRKFVENHFWLPEVYSSEYVSDPQNSLKEHIDQLWPVLTREPQDHIPWSSLLALPQ
                     SYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYY
                     LSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMP
                     DGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRD
                     TGRLASIRTTQFIPIDLNAFLFKLESAIANISALKGEKETEALFRQKASARRDAVNRY
                     LWDDENGIYRDYDWRREQLALFSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGIL
                     ASEYETGEQWDKPNGWAPLQWMAIQGFKMYGDDLLGDEIARSWLKTVNQFYLEQHKLI
                     EKYHIADGVPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP"
     gene            complement(3554..>4069)
                     /locus_tag="RN951_004457"
     CDS             complement(3554..>4069)
                     /locus_tag="RN951_004457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDX2529332.1"
                     /translation="QGASQADELWQKLESYPEALVMLDGDQDGEFCYWLLQKTVVQFP
                     EVKVLITATDCNKRWLQEVIHFNVLAIVPRDSTVETFALAVNSAAMGMMFLPGDWRTT
                     PEKDIKDLKSLSARQREILTMLAAGESNKEIGRALNISTGTVKAHLESLYRRLEVKNR
                     TQAAMMLNISS"
BASE COUNT         1018 a         1074 c          948 g         1029 t
ORIGIN      
        1 tattatcgta ataaaaatcg cccaaacatt cctgttcggg cgatcaaatt aattattgtt
       61 tatcctgcat atacggcgtg tacaccccgt tcagactgtg caggaaagct acgatatcat
      121 ccacatcctc ctgcggcagc tctttgccta cctgatagcg cagcatcagt ttcaccgccc
      181 cgtccagcgt cggcacgtca ccgcgatgga agtacggtgc cgttaaagca acgttacgta
      241 aaccgggtac tttctgacgc aatttatcac gctcttcttt agtcacattc atacgaccaa
      301 tatccgccgc cgtaatttcc ccaaagttaa agtctttttt cagccccaac ggttcaaagg
      361 aacgtccgcc gagaataata ccaccatgac aagttgcaca tttattatct ttaaataatt
      421 gatagccttt tttctgttgc gccgtcagcg cattttcatc tccacgcaac catttatcaa
      481 atggggaatc cggcgtaatt aatgttttct caaattcagc aatggcatca gtaatatttt
      541 cgccactgaa accttgcgga taaacttcga ggaactgcgc tttaagctgc ggatcttttt
      601 ccagcttagc aataatttcg tcccaggatt tcgacgccat ttcaatcggg ttcaacggcg
      661 gtccaccagc ctgatcctgc aatgttgccg cacgaccatc ccagaactgc tcaacgttaa
      721 atactgagtt aaataccgtc ggcgcgttaa tcggcccaac tgcgccacca acaccaatcg
      781 atgtttttct gccatcgacg ccccccgcat tcaacgcatg gcaatgagcg catgaaatgg
      841 tgctatcagc cgataaacgg ggatcgtgat acagcgcaaa acccaacgcc actttttgcg
      901 catcggtagg cagtttttgc gggatgggct gcaccggttc attgcgatgt tccggagcag
      961 tatcattgct ggcgtaatat tccgcgcgct gttttgcaat ccaggccagt atttccgccc
     1021 gctcttcatc actcacctta cccgcccagt gtagcgcggt ataacgcgtt ggtggcatag
     1081 tttcatactg catcacccat tcaatcttat tcaaatcgct ttgcgaaacg ggtttatcag
     1141 ccagcagtgc cgcacgcacg gcctcaaggt taaaagattt atatccaagc ttaatgtcgt
     1201 aatccatcaa ctgtttcgcg ccaggaatat aataataggc gggtaattct gccgaaggcg
     1261 tgtggcaata gtcgcatcct ttttcgcgga gaaagcctaa aaccttatta ttttcactga
     1321 cagcagatgc ctgaacatcg gcctgtttac tgcgtttatt atcgtggtac cacacataac
     1381 cagataaccc taaatagcaa atcgcgacgc cagccaggcc gatcgcggta atacgtgaga
     1441 ccattttcat tattcttccc tcacggtggt gagttattgt gacccagaaa attttccaga
     1501 atgctgcaaa cgtctctgcg agacaaagcc atcataaaaa acagggagat acgctttttg
     1561 ataggaatca atcaattaca tgaatataaa ctatcaataa gatagcctgt gcctattacc
     1621 cagatcagga atggcatatc atgattgcgg cgagagcagg attgaatgtt ctgaaaatga
     1681 aaaacaacac caaatcggta tttttataaa ttccattgat attagtgcgt tatatttttt
     1741 gacaggttaa taaacgtgat ccaccgcacg ctttgtcgcc caccaggcgg agcgaatgac
     1801 tacccttaaa gaaaagccga taattagcga cgaatttcgg aggttggatc cttatgctca
     1861 atcagaaaat tcaaaaccct aatccagacg aactgatgat cgaagtcgat ctctgctatg
     1921 agctggaccc gtatgaatta aaactggatg agatgatcga ggcagaaccg gaacccgaga
     1981 tgattgaagg gctgcctgcc tctgatgcgc tgacgcctgc cgatcgctat ctcgaactgt
     2041 tcgagcatgt tcagtcggcg aaaattttcc ccgacagtaa aacctttccc gactgcgcac
     2101 ctaaaatgga tccgctggat atcttaatcc gctaccgtaa agtgcgccgt catcgtgatt
     2161 ttgacttgcg caagtttgtt gaaaaccact tctggctgcc ggaggtctac tccagcgagt
     2221 atgtatcgga cccgcaaaat tccctgaaag agcatatcga ccagctgtgg ccggtgctaa
     2281 cccgcgaacc acaggatcac attccgtggt cttctctgct ggcgctgccg cagtcatata
     2341 ttgtcccggg cggccgtttt agcgaaacct actattggga ttcctatttc accatgctgg
     2401 ggctggcgga aagtggtcgg gaagatttgc tgaaatgcat ggccgataac ttcgcctgga
     2461 tgatcgaaaa ctacggtcac atccccaacg gcaaccgcac ctattatttg agccgctcgc
     2521 aaccaccggt ttttgcgctg atggtggagt tgtttgaaga agatggtgta cgcggtgcgc
     2581 gccgctatct cgaccacctt aaaatggaat atgccttctg gatggacggt gcagaatcgt
     2641 taatccctaa tcaggcctat cgccatgttg tgcggatgcc ggacggatcg ctgctcaacc
     2701 gttactggga cgatcgcgac acgccgcgtg acgaatcctg gcttgaggac gttgaaaccg
     2761 cgaaacattc tggtcgcccg cccaacgagg tgtaccgcga tttacgcgcg ggggcggcct
     2821 ccggttggga ttactcttcc cgttggctgc gtgatactgg tcgtctggcg agcattcgta
     2881 ccacccagtt catccccatc gatctgaatg ccttcctgtt taaactggag agcgccatcg
     2941 ccaacatctc ggcgctgaaa ggcgagaaag agacagaagc actgttccgc cagaaagcca
     3001 gtgcccgtcg cgatgcggta aaccgttacc tctgggatga tgaaaacggc atctaccgcg
     3061 attacgactg gcgacgcgaa caactggcgc tgttttccgc tgccgccatt gtgccactct
     3121 atgtcggtat ggcgaaccat gaacaggccg atcgtctggc aaacgccgtg cgcagtcggt
     3181 tactgacacc tggcgggatt ctggcaagcg agtacgaaac cggtgaacag tgggataaac
     3241 ccaacggctg ggcaccgtta caatggatgg cgattcaggg atttaaaatg tacggcgatg
     3301 accttctggg tgatgaaatc gcgcgaagct ggctgaagac ggtgaatcag ttctatctgg
     3361 aacagcacaa actgatcgaa aaataccata ttgccgatgg tgttccccgc gaaggcggcg
     3421 gtggcgagta tccgttgcag gatgggtttg gctggactaa cggtgtggta cgccgtttaa
     3481 ttggtttgta cggcgaacca taatattttt acagccagcc gctaacttcc tgctggctgt
     3541 aaaattatcc tcttcaggag gagatattta acatcattgc cgcctgggtg cgatttttca
     3601 cttccagacg gcgatacagg gattccagat gcgcttttac cgttccggta ctgatattca
     3661 gcgctctgcc gatctcctta tttgattcgc ccgccgctaa catggttaaa atctcccgct
     3721 ggcgggcgct taacgatttg agatctttaa tgtccttttc cggcgtcgtc cgccagtctc
     3781 caggcagaaa catcatcccc atcgccgcac tatttaccgc caacgcaaat gtctcgacgg
     3841 ttgaatcacg aggcacaatg gccagcacat taaaatggat aacttcctgt aaccaccgtt
     3901 tattgcaatc cgtcgccgta attaacacct taacctcagg aaattgcacc acggtttttt
     3961 gcagcaacca gtagcaaaac tcaccatcct gatcgccatc gagcataact aaggcttcag
     4021 ggtaactttc cagcttttgc cataactcgt ctgcctgact ggccccctg
//
LOCUS       DAPOAV010000197         4062 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.201, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000197 DAPOAV010000000
VERSION     DAPOAV010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4062
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.201"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            69..164
                     /locus_tag="RN951_004458"
     CDS             69..164
                     /locus_tag="RN951_004458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HDX2529333.1"
                     /translation="MLVFQMRYQMRYVDKTSTVLKQTKKSDYADK"
     gene            290..1027
                     /gene="erm(B)"
                     /locus_tag="RN951_004459"
     CDS             290..1027
                     /gene="erm(B)"
                     /locus_tag="RN951_004459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HDX2529334.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPRVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            972..1142
                     /locus_tag="RN951_004460"
     CDS             972..1142
                     /locus_tag="RN951_004460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA adenine methyltransferase"
                     /protein_id="HDX2529335.1"
                     /translation="MSKYCLFLIVIYYLTGGNNSMSRFCKFGKLHVTKGNVDKLLGIL
                     LTASKELKRSLD"
     gene            1657..2106
                     /locus_tag="RN951_004461"
     CDS             1657..2106
                     /locus_tag="RN951_004461"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529336.1"
                     /translation="MTTILSDYNKSILIELLNTNRQIIVVHGDDIDDYYTDSCYDIIF
                     IDYYDDDDFTYNGQEIWRGDSIYLVKSYQDEIQNRIEKGQELIFVNKENDISFSESIL
                     TYYHLFDYAGKTFEIDGQIIDEQTKVFAAPERRCACRTCWKVPARKT"
     gene            2067..2408
                     /locus_tag="RN951_004462"
     CDS             2067..2408
                     /locus_tag="RN951_004462"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529337.1"
                     /translation="MSHVLEGASQEDLNLYRAEVERDQAYGNWRDFFLNKKGSVTSVS
                     GDANLDQIADVSYLLDTFFAKVTRTALQNAASIAGLMITTEAMVAEAPKKDEPAMPPG
                     GGMGGMGGMDF"
     gene            2635..>4062
                     /locus_tag="RN951_004463"
     CDS             2635..>4062
                     /locus_tag="RN951_004463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019726358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDX2529338.1"
                     /translation="MPRLATSRRQAAGCAPLPSAHTGSRYARHAPERTLLYALVEAHY
                     PDFIARIEAEGRSLPGYVREAFDAYLRCGVLEHGFLRVVCEHCRAERLVAFSCKKRGF
                     CPSCGARRMAESARHLVEEVFGPRPVRQWVLSFPYPLRFLFASKPEAIGPVLGIVQRV
                     IAGWLADQAGIDRASAQCGAVTLIQRFGSALNLNIHFHMLWLDGVYVEATELPRRELR
                     LHRARAPTTAQLTQLAAAIAHRVCRHLTRKGWLEGEGESAFLADSAAGDDSMDGLRMS
                     SITYRIATGRDAGCKVVTLQTLPGDAGSLEGEAGKVGGFSLHAGVAAEAHESHKLEKL
                     CRYITRPAISEKRLSIALQGRVRYQLKTPWRNGTTHVEWDPVDFIAKLAALVPPPRAH
                     LTRFHGVFAPNAALRAQLTPSGRGRRHDAAVEPADASANDAPRSPEEKRRSMSWAQRL
                     KRVFSIDVTACVHCGGTVRIVASIEE"
BASE COUNT         1091 a         1012 c         1025 g          934 t
ORIGIN      
        1 ttttgtataa taggaattga agttaaatta gatgctaaaa atttgtaatt aagaaggagg
       61 gattcgtcat gttggtattc caaatgcgtt atcaaatgcg ttatgtagat aaaacatcta
      121 ctgttttgaa acagactaaa aaaagtgatt acgcagataa ataaatacgt tagattaatt
      181 cctaccagtg actaatctta tgacttttta aacagataac taaaattaca aacaaatcgt
      241 ttaacttctg tatttgttta tagatgtaat cacttcagga gtaaattaca tgaacaaaaa
      301 tataaaatat tctcaaaact ttttaacgag tgaaaaagta ctcaaccaaa taataaaaca
      361 attgaattta aaagaaaccg ataccgttta cgaaattgga acaggtaaag ggcatttaac
      421 gacgaaactg gctaaaataa gtaaacaggt aacgtctatt gaattagaca gtcatctatt
      481 caacttatcg tcagaaaaat taaaactgaa tactcgtgtc actttaattc accaagatat
      541 tctacagttt caattcccta acaaacagag gtataaaatt gttgggaata ttccttacca
      601 tttaagcaca caaattatta aaaaagtggt ttttgaaagc catgcgtctg acatctatct
      661 gattgttgaa gaaggattct acaagcgtac cttggatatt caccgaacac tagggttgct
      721 cttgcacact caagtctcga ttcagcaatt gcttaagctg ccagcggaat gctttcatcc
      781 taaaccaaga gtaaacagtg tcttaataaa acttacccgc cataccacag atgttccaga
      841 taaatattgg aagctatata cgtactttgt ttcaaaatgg gtcaatcgag aatatcgtca
      901 actgtttact aaaaatcagt ttcatcaagc aatgaaacac gccaaagtaa acaatttaag
      961 taccgttact tatgagcaag tattgtctat ttttaatagt tatctattat ttaacgggag
     1021 gaaataattc tatgagtcgc ttttgtaaat ttggaaagtt acacgttact aaagggaatg
     1081 tagataaatt attaggtata ctactgacag cttccaagga gctaaagagg tccctagact
     1141 agcaagaagt acacaagaag ccttaaagat tatagaaaag cttttccatg aaatgcttaa
     1201 cattatttaa tgttaacatg tggctttgtg gtaactacca cgagtggtaa cttgtaacat
     1261 gaaaaaagtt acaagttaca agtggtttat ttacgaacat aaaggctagg aaagcacttg
     1321 ataagtatat caagtgcttt ttttccgttc gattttacta tccaagatac cgcttgacgt
     1381 acctaatatt ttagtgtgct aagggctttg ctttttctgg ttatagttcg ttcaaaaaag
     1441 accgcaaggg taaatgcacg atcatagatc gcccttgcag ctttttaatc tctccacttt
     1501 tttataacca agcaaaccac caagcacact gaaaaaataa ttaggaacta aagcgaagtg
     1561 cgtatcttgg ataaatcttc actcgatttt aaaagattaa gcacccagcc aaagcgccta
     1621 aaaaaataat ttttttaaag aaaggaagta atttaaatga ctacaatttt aagcgactac
     1681 aataaatcta tcctaattga attactaaac accaatcgcc aaattatcgt cgttcatggc
     1741 gacgatattg atgattatta cacagattct tgctatgaca ttatctttat tgattactat
     1801 gatgatgatg atttcactta taacggacag gaaatatggc gtggcgatag catttatctt
     1861 gtaaaaagtt atcaagatga aattcaaaac cgtatagaaa aaggacaaga gctgatattt
     1921 gttaataaag aaaatgatat atcattttca gaatctattt taacttatta ccatctattt
     1981 gattatgctg gtaaaacgtt tgaaatagac ggtcaaatca ttgatgaaca aacaaaagtt
     2041 tttgccgcac ccgagcgccg ctgcgcatgt cgcacgtgct ggaaggtgcc agccaggaag
     2101 acctgaacct ttaccgcgcg gaagtggagc gcgaccaggc ctatggcaac tggcgcgatt
     2161 tcttcctgaa caagaagggc agcgtcacat ccgtgagcgg tgatgccaac ctcgaccaga
     2221 tcgcggacgt gtcgtacctg ctggatacct tctttgccaa ggtcacccgc accgcgttgc
     2281 agaacgccgc ctccatcgcg ggcctgatga tcaccaccga agccatggtg gccgaggccc
     2341 cgaagaagga cgagccggcg atgccgccgg gcggcggcat gggtggcatg ggcggcatgg
     2401 atttctgatg cggttggccc ggtcgtcagg gaaccggacc gcgccagcgc ggtccgatcc
     2461 cggcaacgac ccgacatcaa ggccccaagg acggggccgg agcccggcag cgatgccggg
     2521 ctttttgttg tgcccgcgcc gcggcaatgt ctgacgcgaa gatcagaacg caccgatacg
     2581 aacgtgcgaa cacaggtgca accctgagca gccgtccccg caccggagcg ctgcgtgccg
     2641 cgcctcgcca catcccggcg gcaagccgcg ggatgcgcgc cactgccgtc cgcccacacc
     2701 ggttcgcggt acgcgcgcca cgcgcccgag cgcacgctgc tgtacgcgtt ggtagaggcg
     2761 cactacccgg acttcattgc acggatcgaa gcggagggcc gctcgctgcc cgggtatgtc
     2821 cgcgaggcgt tcgatgccta cctgcgttgc ggcgtgctcg agcacggctt cctgcgggtg
     2881 gtgtgcgagc actgccgtgc agagaggctg gtggccttct cctgcaagaa gcgcgggttc
     2941 tgcccgagtt gcggcgcgcg acgcatggcc gagagtgcgc ggcacctggt cgaggaggtg
     3001 ttcggcccgc ggcctgtgcg gcaatgggtg ctgagctttc cgtacccctt gcgtttcctg
     3061 ttcgccagca agccagaagc cattggcccg gtgctgggca tcgtgcagcg cgtgatcgcc
     3121 ggctggttgg ccgatcaagc cggcatcgac cgcgccagcg cccagtgcgg cgcggtgacg
     3181 ctgatccagc gtttcggcag cgcgctgaac ctgaacatcc acttccacat gctgtggctc
     3241 gacggcgtgt acgtggaagc caccgagctg ccgcggcgcg aactgcgcct gcaccgcgcc
     3301 cgtgcgccca ccaccgcgca gttgacccag ctggcagctg ccatcgcgca ccgggtgtgt
     3361 cggcacctga cgcgcaaagg ctggctcgaa ggggagggcg aatcggcctt cctggcagac
     3421 agcgctgcag gcgacgacag catggatggg ctgcggatga gttcgatcac ctaccgcatc
     3481 gccaccggcc gcgacgctgg ctgcaaggtc gtcacgctgc aaacgctgcc cggtgacgcc
     3541 ggttcgctgg agggcgaagc cggcaaggtc ggcggcttct cactgcatgc cggcgtggcg
     3601 gccgaagcac acgaaagcca caagctggaa aagctgtgcc gctacatcac gcgcccggcg
     3661 atcagcgaga agcggctgtc gatagcgctc cagggcaggg tgcgttacca gctcaagacc
     3721 ccgtggcgca atggcaccac gcatgtggaa tgggatccgg tggatttcat cgccaagctg
     3781 gcggcgctgg tcccgccacc gcgcgcccac ctgacccgct tccacggggt gtttgccccg
     3841 aacgccgccc tgcgcgcaca gctgacgcca tcggggcgcg gcaggcggca tgacgccgct
     3901 gtggagccgg cggacgcaag cgcgaacgac gcgccgcgca gccccgagga gaagcgccgt
     3961 tcgatgagct gggcgcaacg cctcaagcgg gtcttttcca tcgacgtcac cgcctgcgtc
     4021 cactgcggtg gcaccgtgcg gatcgtcgcc agcatcgagg aa
//
LOCUS       DAPOAV010000198         4031 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.202, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000198 DAPOAV010000000
VERSION     DAPOAV010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4031
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.202"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..777
                     /locus_tag="RN951_004464"
     CDS             <1..777
                     /locus_tag="RN951_004464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS150 family transposase"
                     /protein_id="HDX2529339.1"
                     /translation="TFYYHLKALSKPDKYADVKKRISEIYHENRGRYGYRRVTLSLHR
                     EGKQINHKAVQRLMGTLSLKAAIKVKRYRSYRGEVGQTAPNVLQRDFKATRPNEKWVT
                     DVTEFAVNGRKLYLSPVIDLFNNEVISYSLSERPVMNMVENMLDQAFKKLNPHEHPVL
                     HSDQGWQYRMRRYQNILKEHGIKQSMSRKGNCLDNAVVECFFGTLKSECFYLDEFSNI
                     SELKDAVTEYIEYYNSRRISLKLKGLTPIEYRNQTYMPRV"
     gene            877..1035
                     /locus_tag="RN951_004465"
     CDS             877..1035
                     /locus_tag="RN951_004465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HDX2529340.1"
                     /translation="MKLPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGHREVAA
                     FMAYESGK"
     gene            1956..2243
                     /locus_tag="RN951_004466"
     CDS             1956..2243
                     /locus_tag="RN951_004466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001825190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529341.1"
                     /translation="MSTRNIHVNTASYTLLVAGKKKNTGEEWDVLEFSSLTELKKYRK
                     SHPEKMAFSYSYALSQGVDKQFRHINIAEADHFKQFLRQIKRAGLDIRAIC"
     gene            2361..3182
                     /locus_tag="RN951_004467"
     CDS             2361..3182
                     /locus_tag="RN951_004467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HDX2529342.1"
                     /translation="MRLASRFGRYNSIRRERPLTDDELMQFVPSVFSGDKHESRSERY
                     TYIPTINIINKLRDEGFQPFFACQSRIRDLGRREYSKHMLRLRREGHINGQEVPEIIL
                     LNSHDGSSSYQMIPGIFRFVCTNGLVCGNNFGEIRVPHKGDIVGQVIEGAYEVLGVFD
                     KVTDNMEAMKEIHLNSDEQHLFGRAALMVRYEDENKTPVTPEQIITPRRREDKQNDLW
                     TTWQRVQENMIKGGLSGRSASGKNTRTRAITGIDGDIRINKALWVIAEQFRKWKS"
     gene            complement(3479..>4031)
                     /locus_tag="RN951_004468"
     CDS             complement(3479..>4031)
                     /locus_tag="RN951_004468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000614282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HDX2529343.1"
                     /translation="WVKLFTDKVTRGGKMKKWMLTICLMFINEICQATDCFDLAGRDY
                     KIDPDLLRAISWQESRYRVNAIGINPVTGYGSGLMQVDSQHFNELARYGIKPEHLTTD
                     PCMNIYTGAYYLAIAFKKWGVTWEAVGAYNAGFRKTERQNQRRLAYASDVYRIYTGIK
                     SSKGIRLPATKKSLPEINSVQNN"
BASE COUNT         1027 a          938 c         1006 g         1060 t
ORIGIN      
        1 acgttttatt atcatctaaa ggctctcagc aagcctgaca agtatgcgga cgttaaaaag
       61 cgtattagtg agatttatca cgagaataga ggccgatacg gataccgtag ggtaacgctg
      121 tctcttcatc gagaagggaa acagattaac cataaagctg ttcagcgcct gatgggaacc
      181 ctctcactta aagcagcgat taaggtcaag cgataccgct cttacagagg agaggtaggg
      241 caaaccgccc ctaatgttct ccaaagagat ttcaaggcta cgcggccaaa cgagaagtgg
      301 gttaccgatg ttactgaatt tgcagtcaat gggcgcaagc tgtatttgtc tccagtaata
      361 gatctcttca acaacgaagt tatttcttac agcctttcgg aaagaccagt gatgaacatg
      421 gttgagaata tgctcgatca ggcattcaaa aagcttaatc ctcacgagca tcctgttctg
      481 cactctgacc agggatggca gtatcgtatg agaagatatc aaaatatcct taaagaacat
      541 ggtattaaac aaagcatgtc cagaaaaggc aattgtctgg ataatgctgt ggtggagtgt
      601 ttctttggaa ccttaaagtc ggagtgtttt tatcttgatg agttcagtaa tataagcgaa
      661 ctgaaggatg ctgttacgga atatattgaa tactacaaca gcagaagaat tagcctgaaa
      721 ttaaaaggtc tgactccaat tgaatatcgg aatcagacct atatgcctcg tgtttaactg
      781 tccaactttt tggggtcagt acaccacgag gcatccctat gtctagtaca catcaggata
      841 gcctcttacc gcgctttgcg caaggagaag aaggccatga aactaccacg aagttccctt
      901 gtctggtgtg tgttgatcgt gtgtctcaca ctgttgatat tcacttatct gacacgaaaa
      961 tcgctgtgcg agattcgtta cagagacgga cacagggagg tggcggcttt catggcttac
     1021 gaatccggta agtagcaacc tggaggcggg cgcaggcccg ccttttcagg actgatgctg
     1081 gtctgactac tgaagcgcct ttataaaggg gctgctggtt cgccggtagc ccctttctcc
     1141 ttgctgatgt tgtacgggca tgaacaacct gacttcagga aggtcgtttc ccttcaggaa
     1201 cggggatgaa cgcgcgcctg cggcgcccgt tcttttcccc cgccttctct ggttatggcc
     1261 tgtcagaaat cacatcacct tccctgtgat tattctcttt ttcttcctgc tctgattctg
     1321 actactgcag tgttgtcctg tctgccgggc gtaccttcgg ctcccggctg cctggcggca
     1381 tccggtcgtc aggcccgact ccgacaggca gctgctggcg cacctgccag tctccgccga
     1441 acccgctggc gcggtttcgg gctgttgcta cggtccgatg cgtgaaaacc cctggcttgc
     1501 agcgaccgtt ccggtcgcgc cgcctctgtc gcgccgtgac ctgcgctccc ggcatcccgg
     1561 caaaaggcgc cgggatgtaa ggcgcaacgc cgtttcgcaa accgcgcttc acgtcgttgc
     1621 ggcgggtccc tgcccgttgt tgtgtccggt gccattcacc agtttaagcc cctgtcgccg
     1681 ggggcataga cagccacaac cgtctccgcc agtccagggg tgaaatgcac atcccgcaaa
     1741 actttttgcc cagaagcagg caaaaacttt tgcggtctgc ccccggacag tcgtttccgg
     1801 ccgtggcagt gatgccccat gcggcgaagg ttctcaaaca ggtgatggtg aataccggag
     1861 ggaacaaaag gcaggtcccc gcaaaacgtc aaaaccgcgg ctcccgaaac tcaacagatg
     1921 atgggggctg aaaaccagag agaggagaaa gcaggatgag tacccgaaat atccacgtta
     1981 acaccgcgtc gtacacgctt cttgttgccg ggaagaaaaa aaacaccggg gaagagtggg
     2041 acgtcctgga attcagcagc ctgactgagc tgaaaaaata tcgcaaaagc cacccggaaa
     2101 agatggcctt cagttatagc tacgcgctca gtcagggtgt ggataagcag ttccgccata
     2161 tcaacattgc ggaagccgat cacttcaaac agttcctgcg tcagattaag cgtgccggcc
     2221 tcgatatccg ggcgatctgc tgaccggatg tgatgaatat ccctcctgat tgttgcaatc
     2281 ttgttaatgg agatcggggg gatgatatta agcggaaaaa ttttttatta aatttattct
     2341 ttcataaagg agtagctgtt atgcgattag cttcccgttt tggtcggtat aattccatcc
     2401 gccgtgaacg tcctttaacg gatgatgaat taatgcagtt cgtgccttcg gtattttccg
     2461 gtgataaaca tgagtcccgg agtgaacgtt atacgtatat tccaacaatc aatatcatca
     2521 ataagttacg tgatgaaggt ttccagccat tctttgcctg tcagagtcgg attcgtgatt
     2581 tgggacgtcg cgaatacagt aaacatatgt tacgtcttcg cagggaaggg catattaacg
     2641 gacaggaagt tcctgaaatt atcctgctta attcacatga tggttcatcc agttatcaga
     2701 tgatccccgg aatttttcgt tttgtctgca caaatggcct ggtgtgcgga aataattttg
     2761 gcgaaatccg cgttccacat aaaggtgata ttgtcgggca ggttatcgag ggagcgtatg
     2821 aagtgctcgg tgtctttgat aaggtcactg ataatatgga ggcgatgaaa gaaattcatc
     2881 ttaacagtga cgagcaacat ttatttggca gagctgcact gatggtcagg tatgaagatg
     2941 aaaataaaac gccagtgaca cctgaacaga taattactcc ccgtcgtcgg gaagacaaac
     3001 agaacgatct ctggacaacc tggcagcggg ttcaggagaa tatgataaaa ggtggattat
     3061 cggggcgaag tgcctccggg aaaaatacca ggacaagagc cattacaggt attgatggtg
     3121 atataagaat caacaaggcg ttatgggtga ttgccgaaca gttcagaaag tggaagtcat
     3181 gataatataa gtaaagcccc gaaaaaattt tcggggcttt acttatatta tcatttttcg
     3241 gcattgctgt gtcgtctgat atacctcaat ttcatcaacc ggctttccgg ttgtctgtaa
     3301 atattgtgcc cgcgaaaaat ggtctggcag gaggctgcac agttaccggg tatatataag
     3361 atgggttccc gcttcgcggg gcttcggcca gtcagtattg tcactcatat gatatttttg
     3421 tgtgtggcct tccatgccgc ttttgcggca taaccggtat ctgacaatgt ctgtaagatt
     3481 aattgttctg cacgctgtta atttccggaa gtgatttctt cgtggccgga agccggatac
     3541 ctttactgct ttttatccca gtataaatcc ggtaaacatc tgatgcgtag gcaagacgtc
     3601 tctggttctg gcgttcggtt ttcctgaatc cggcattgta tgcaccaacg gcctcccagg
     3661 tgacgcccca ttttttaaat gctattgcca gataataagc accggtataa atgttcatgc
     3721 agggatctgt tgtcagatgt tctggcttaa ttccgtagcg ggccagttcg ttaaaatgct
     3781 gggaatctac ctgcatcagt ccgctgccat atcccgttac cggattaata ccgatggcat
     3841 taacccggta acgggattct tgccatgata ttgctctcag taaatcagga tctattttgt
     3901 aatcccggcc tgcaagatca aagcaatcag tggcctggca gatctcattt ataaacatca
     3961 ggcagatggt taacatccat tttttcattt ttccacctct ggtgacttta tccgtaaata
     4021 atttaaccca c
//
LOCUS       DAPOAV010000199         4030 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.203, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000199 DAPOAV010000000
VERSION     DAPOAV010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4030
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.203"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..624
                     /locus_tag="RN951_004469"
     CDS             <1..624
                     /locus_tag="RN951_004469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS element protein"
                     /protein_id="HDX2529344.1"
                     /translation="DEWGNLLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQ
                     GRYITQDPIGLKGGWNFYQYPLNPVTNTDPLGLEVFPRPFPLPIPWPKSPAQQQADDN
                     AAKALTKWWNDTASQRIFDSLILNNPGLALDITMIASRGNVADTGITDRVNDIINDRF
                     WSDGKKPDRCDVLQELIDCGDISAKDAKSTQKAWNCRHSRQSNDKKR"
     gene            645..1487
                     /locus_tag="RN951_004470"
     CDS             645..1487
                     /locus_tag="RN951_004470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HDX2529345.1"
                     /translation="MSNTYQKRKASKEYGLYNQCKKLNDDELFRLLDDHNSLKRISSA
                     RVLQLRGGQDAVRLAIEFCSDKNYIRRDIGAFILGQIKICKKCEDNVFNILNNMALND
                     KSACVRATAIESTAQRCKKNPIYSPKIVEQSQITAFDKSTNVRRATAFAISVINDKAT
                     IPLLINLLKDPNGDVRNWAAFAININKYDNSDIRDCFVEMLQDKNEEVRIEAIIGLSY
                     RKDKRVLSVLCDELKKNTVYDDIIEAAGELGDKTLLPVLDTMLYKFDDNEIITSAIDK
                     LKRS"
     gene            1515..2473
                     /locus_tag="RN951_004471"
                     /pseudo
     CDS             1515..2473
                     /locus_tag="RN951_004471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312497.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
     gene            2485..2946
                     /locus_tag="RN951_004472"
     CDS             2485..2946
                     /locus_tag="RN951_004472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDX2529346.1"
                     /translation="MKACLLLFFYFSFICQLHGADVKIKQNESMMGSTAMTYDLSEEK
                     LMKLKYKSQHGDSEASFRLYQYYCFTKNNIYKQLRFLERSASQGNVTAQFNYGVFLSD
                     TNPTLSEYYNLNRAIYWMEFAVNNGNIDAKSKLQELKKLKRMDRRKNKENP"
     gene            3653..3988
                     /locus_tag="RN951_004473"
     CDS             3653..3988
                     /locus_tag="RN951_004473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529347.1"
                     /translation="MADKAILWALISASTKEGRKACSLSYFACKAAEAELGLAYMAAN
                     DNKEFLTSLSNIMRYKIDAGLSESYTCYLLSKGKIIRPYLKNLNPLQLAADCIETVNK
                     IKDKNKKNH"
BASE COUNT         1323 a          716 c          893 g         1098 t
ORIGIN      
        1 gatgaatggg gcaacctgct gaatgaagag aacccgcatc agctgcagca gcttatccgc
       61 ctgccggggc agcagtatga tgaggagtcc ggcctgtatt acaaccgcca ccgctattat
      121 gacccgctgc aggggcggta tatcactcag gatccgattg ggctgaaggg gggatggaat
      181 ttttatcagt atccgttgaa tccagttacg aatacagatc ctctggggtt agaagttttt
      241 cctagaccat tccccttgcc aattccatgg cccaaaagcc ctgcacagca gcaagcagat
      301 gataatgctg caaaagcatt gacaaaatgg tggaacgata cagcatcaca aagaatattt
      361 gactctctaa tattgaataa tccgggacta gcattagata taacaatgat agcttctcgt
      421 ggaaatgttg cagacacagg gataactgat cgtgtcaatg acataataaa tgacagattc
      481 tggagtgatg ggaaaaaacc cgacagatgt gacgtacttc aggaactaat tgattgtggt
      541 gatattagtg ctaaagatgc aaaaagcaca cagaaagcct ggaattgtcg tcactccaga
      601 cagtcaaacg ataaaaaaag atagcccttg tggaggttcc tgcaatgtca aatacatacc
      661 agaaaagaaa ggcaagtaaa gagtatggtt tatataatca atgtaagaaa ctaaatgatg
      721 atgaattatt tcgcttactt gatgatcaca attccttgaa aaggatttca tctgccagag
      781 tattacagtt aagaggtggg caagacgctg ttagattggc aattgagttc tgctctgata
      841 aaaattatat ccgtagagat atcggagcat ttatactcgg gcaaataaaa atttgcaaaa
      901 aatgcgaaga taatgttttt aatattttga acaatatggc attgaatgat aagagcgctt
      961 gcgttcgagc tacggcaatc gagtcaacgg ctcagcgatg caagaaaaac ccaatttatt
     1021 cacctaaaat agtagaacaa tctcaaatta ctgcttttga taaatcgact aatgtcagac
     1081 gtgctacagc atttgctatt tctgttatca atgataaagc aacaattcca ctattgatta
     1141 atctgttaaa agatccaaat ggagatgtca gaaactgggc cgcatttgca ataaatatca
     1201 ataaatatga taatagtgat attagggatt gttttgtgga gatgcttcag gataaaaatg
     1261 aggaagtccg tattgaagca ataatcggac tttcctacag aaaagataaa agggttttat
     1321 ctgttttatg cgatgagtta aaaaaaaata ctgtttatga tgatatcatt gaagctgcgg
     1381 gtgaattagg tgataaaacg ctacttcctg ttttagatac tatgttgtac aagtttgatg
     1441 acaatgaaat tataacttcc gctattgata agctgaagcg ttcatagcgt gagttgccta
     1501 tgcacagtgg gggattcccg ccggcacggt gcagatgctc gaccggctgg aaagtgaaat
     1561 cctggctgac cgggtgagtg aggaaagccg ccgctggctg gcatcgtgcg gcctgaccgt
     1621 ggagcagatg aaaaaccaga tggacccggt gtacacgccg gcgcgaaaaa tccacctgta
     1681 ccactgcgac catcgcggcc tgccgctggc gctcatcagc acggaagggg caacagcgtg
     1741 gtgcgcagaa tatgatgaat ggggcaacct gctgagtgat gagaacccgc atcatctgca
     1801 gcagctcatt cgcctgccgg gtcagcagta tgatgaggag tccggcctgt attacaaccg
     1861 ccaccgctat tatgacccgc tgctggggcg gtatatcact caggatccga ttggactgaa
     1921 ggggggatgg aatttttatc agtatccgtt gaatccggtc ataaatgtag atccgcaagg
     1981 tttggttgat ataaatttat accccgaaag tgatcttatc cattctgtag ctgatgagat
     2041 taatatccca ggcgttttca caatcggggg gcatggtacc cccacatcta ttgaatccgc
     2101 aacgcgcagt atcatgacag ctaaagatct agcatatcta attaaatttg atgggaatta
     2161 taaagatggg atgacagttt ggttattttc ttgtaataca ggtaaaggac aaaattcatt
     2221 tgctagccaa ttagctaaag agttacatac aaatgtaata ggacctgaca cgctatggac
     2281 gtggtggggg cgaggaacta atggtaagtt aaaaatggat acagtgctaa cagcaccaac
     2341 gaaccttaat tcaaataagg atctaatggc tataacaaca aaagaccttg gtaattggat
     2401 aacatatggg ccatctgggc accccatttc taatatgcaa ggtacgccag aaaaacccag
     2461 tgatataaga taggttgtag atgtatgaaa gcatgcttgt tactattttt ttatttctct
     2521 tttatttgtc aattgcatgg tgctgatgtg aaaataaaac aaaacgaaag tatgatgggg
     2581 tctacagcaa tgacctatga tttaagtgaa gaaaagttga tgaaactgaa gtataaatca
     2641 caacatggtg attcagaggc atcatttcga ctatatcaat attactgctt tactaaaaat
     2701 aacatttaca aacaattgcg attcttggaa agatcagcat ctcaggggaa tgttacagcg
     2761 cagtttaatt atggggtctt tttatcagat acaaatccaa cattatcaga atattataat
     2821 ttgaatagag ctatttattg gatggaattc gctgtaaata acggtaatat tgatgcaaag
     2881 agcaaacttc aagagctcaa aaagctaaag cgaatggata gaaggaagaa taaggagaat
     2941 ccgtaaaagc aatagttcat cagactgccg cagcagtagt atgatgatga atcagggctg
     3001 tactataact attatcggta acattaaccg cagcaggggc ggtataacac tcaggctccg
     3061 attgggctgg aaggtaggtg gaatttttat cagtatccgt tgaacccgat ttctggaatc
     3121 gatccccttg ggattagcca cctgtttata cagcataact ttaggtatgc tttcgtgtgt
     3181 ttcagatata ccatgtgatg ataattttta tgatgtgctt agtattccag tcgcttctgg
     3241 taataatatg caatgtaaaa ataatccccg ttgtacacat ttataaatag atggccaata
     3301 cctcaaggcc tatggagttg gaatgttaat gacccgggag caagcaatag aaaacctgac
     3361 ggcatacgat tagtaccgtc agttaataca ggaacttata atcgcaatgg attttcaata
     3421 catagttgtt taaacgcttt tggtccgtct ttaggacctc gattctgttc cgagggttgt
     3481 ataactggtt tatctaatga catgcaaaaa ttaaatgagt taatattttc agagccagat
     3541 agcacattaa cagttacgga ctaaaaaata tggcaaggtt attaacaatt gtattttttt
     3601 ctctatttct gcgagtgcag ttactgcaag acaatttcag agagagttag atttggcaga
     3661 caaagcaata ttatgggcac taatatcagc cagtactaaa gagggacgaa aagcgtgttc
     3721 actaagctat tttgcctgta aggccgcaga ggctgaactc ggactggcat atatggctgc
     3781 gaatgataac aaggaatttc tcacatcctt atctaatata atgaggtaca aaatagatgc
     3841 tggactttcc gaatcctata catgctattt attaagtaag ggaaagatca taagaccata
     3901 tctgaaaaat ctaaatccac tccaacttgc cgctgattgc attgaaacag taaataaaat
     3961 aaaagataag aataaaaaaa atcattgata taaattcagt taatatttgt agtgatgata
     4021 aaaatataaa
//
LOCUS       DAPOAV010000200         3999 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.204, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000200 DAPOAV010000000
VERSION     DAPOAV010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3999
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.204"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..3744
                     /locus_tag="RN951_004474"
     CDS             <1..3744
                     /locus_tag="RN951_004474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001530200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HDX2529348.1"
                     /translation="ALPPDIRLSPHLYLATNSAQGPWWILGWSERVPGAEDVLPAPLP
                     PYRVLTGMADRFGRTLTYRREAAGDLAGEITGVTDGAGREFRLVLTTQAQRAEEARTS
                     SLSSSDSSRPLSASAFPDTLPGTEYGPDRGIRLSAVWLMHDPAYPESLPAAPLVRYTY
                     TEAGELLAVYDRSNTQVRAFTYDAQHPGRMVAHRYAGRPEMRYRYDDTGRVVEQLNPA
                     GLSYRYLYEQDRITVTDSLNRREVLHTEGGAGLKRVVKKELADGSVTRSGYDAAGRLT
                     AQTDAAGRRTEYGLNVVSGDITDITTPDGRETKFYYNDGNQLTAVVSPDGLESRREYD
                     EPGRLVSETSRSGETVRYRYDDAHSELPATTTDATGSTRQMTWSRYGQLLAFTDCSGY
                     QTRYEYDRFGQMTAVHREEGISLYRRYDNRGRLTSVKDAQGRETRYEYNAAGDLTAVI
                     TPDGNRSETQYDAWGKAVSTTQGGLTRSMEYDAAGRVISLTNENGSHSVFSYDALDRL
                     VQQGGFDGRTQRYHYDLTGKLTQSEDEGLVILWYYDESDRITHRTVNGEPAEQWQYDG
                     HGWLTDISHLSEGHRVAVHYGYDDKGRLTGECQTVENPETGELLWQHETKHAYNEQGL
                     ANRVTPDSLPPVEWLTYGSGYLAGMKLGGTPLVEYTRDRLHRETVRSFGSMAGSNAAY
                     ELTSTYTPAGQLQSQHLNSLVYDRDYGWSDNGDLVRISGPRQTREYGYSATGRLESVR
                     TLAPDLDIRIPYATDPAGNRLPDPELHPDSTLTVWPDNRIAEDAHYVYRHDEYGRLTE
                     KTDRIPAGVIRTDDERTHHYHYDSQHRLVFYTRIQHGEPLVESRYLYDPLGRRMAKRV
                     WRRERDLTGWMSLSRKPEVTWYGWDGDRLTTVQTDTTRIQTVYEPGSFTPLIRVETEN
                     GEREKAQRRSLAETLQQEGSENGHGVVFPAELVRLLDRLEEEIRADRVSSESRAWLAQ
                     CGLTVEQLARQVEPEYTPARKVHFYHCDHRGLPLALISEDGNTAWRGEYDEWGNQLNE
                     ENPHHLHQPYRLPGQQHDEESGLYYNRHRHYDPLQGRYITPDPIGLRGGWNMYQYPLN
                     PIQVIDPMGLDAIENMTSGGLIYAVSGVPGLIAANSITNSAYQFGYDMDAIVGGAHNG
                     AADAMRHCYLMCRMTKTFGSTIADVIGKNHEAAGDRQGQPAKERIMDLKNNTVGIACG
                     DFSAKCSDACIEKYNTGQLFGLDGIKADNPIKAKQGSSDASNY"
     gene            3728..>3999
                     /locus_tag="RN951_004475"
     CDS             3728..>3999
                     /locus_tag="RN951_004475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529349.1"
                     /translation="MLQIIRGKLVIFLITLCLFVVYLGFDNNSNSDIVFYGHKTPKSV
                     EIYLSEKNIIYKIINDQKISRGNGHFISIMVNNYRTHCGVVDINLN"
BASE COUNT          952 a         1054 c         1291 g          702 t
ORIGIN      
        1 gcgctgccgc cggatatccg gttaagcccg catctttacc tggcgaccaa cagcgcacag
       61 gggccgtggt ggatactggg gtggtctgag cgggtgccgg gtgctgagga cgtactgcca
      121 gcgccgctgc cgccgtaccg ggtgcttacc gggatggcgg accgcttcgg gcggacgctg
      181 acgtaccggc gtgaggccgc cggtgacctg gccggggaaa tcaccggcgt gacggacggt
      241 gccgggcggg agttccgtct ggtgctgacc acgcaggcgc agcgtgcgga agaggcccgc
      301 acctcttcgc tatcttcttc tgacagttcc cgccctctct cagcctcagc gttccccgac
      361 acactgcccg gtaccgaata cggccccgac aggggtatcc gcctttcggc ggtgtggctg
      421 atgcacgacc cggcataccc ggagagcctg cccgctgcgc cactggtgcg gtacacgtat
      481 acggaagccg gtgaactgct ggcggtatat gaccgcagca atacgcaggt gcgcgctttc
      541 acgtatgacg cgcagcaccc gggccggatg gtggcgcacc gttacgcggg aaggccggag
      601 atgcgctacc gctacgacga tacggggcgg gtggtggagc aactgaaccc ggcagggtta
      661 agctaccgct atctttatga gcaggaccgc atcaccgtca ccgacagcct gaaccggcgt
      721 gaggtgctgc atacagaagg cggggccggg ctgaaacggg tggtgaaaaa agaactggcg
      781 gacggcagcg tcacgcgcag cgggtatgac gcggcaggaa ggctcacggc gcagacggac
      841 gcggcgggac ggaggacaga gtacggtctg aatgtggtgt ccggcgatat cacggacatc
      901 accacaccgg acgggcggga gacgaaattt tactataacg acgggaacca gctgacggcg
      961 gtggtgtccc cggacgggct ggagagccgc cgggaatatg atgaaccggg caggctggta
     1021 tcggagacat cgcgcagcgg ggagacagta cgctaccgct acgatgacgc gcacagtgag
     1081 ttaccggcga cgacaacgga tgcgacgggc agcacccggc agatgacctg gagccgctac
     1141 gggcagttgc tggcgttcac cgactgctcg ggctaccaga cccgttatga atacgaccgc
     1201 ttcggccaga tgacggcggt ccaccgcgag gaaggcatca gcctttaccg ccgctatgac
     1261 aaccgtggcc ggttaacctc ggtgaaagac gcacagggcc gtgaaacgcg gtatgaatac
     1321 aacgccgcag gcgacctgac tgccgttatc accccggacg gcaaccggag cgagacacag
     1381 tacgatgcgt ggggaaaggc ggtcagcacc acgcagggcg ggctgacgcg cagtatggag
     1441 tacgatgctg ccggacgtgt catcagcctg accaacgaga acggcagcca cagcgtcttc
     1501 agttacgatg cgctggaccg gctggtacag cagggcggct ttgacgggcg gacgcaacgt
     1561 tatcattatg acctgaccgg aaaactcaca cagagtgagg atgagggact tgtcatcctc
     1621 tggtactacg atgaatcgga ccgtatcact caccgcacgg tgaacggcga accggcagag
     1681 cagtggcagt atgatggcca cggctggctg acagacatca gccacctgag cgaaggccac
     1741 cgtgttgccg tccactatgg ctatgacgat aaaggccgcc tgaccggcga atgccagacg
     1801 gtggagaacc cggagacggg ggaactgctg tggcagcatg agacgaaaca cgcatacaac
     1861 gagcaggggc tggcaaaccg cgtcacgccg gacagcctgc cgccggtgga gtggctgacg
     1921 tatggcagcg gttacctggc gggaatgaag ctgggcggga cgccgctggt cgagtatacg
     1981 cgggacaggc tgcaccgtga gacggtgcgc agcttcggca gcatggcagg cagtaatgcc
     2041 gcatacgaac tgaccagcac atacaccccc gcaggccagt tacagagcca gcacctgaac
     2101 agcctggtat atgaccgtga ctacgggtgg agtgacaacg gcgacctggt gcgcatcagc
     2161 ggcccgcgac agacgcggga atacggctac agcgccacgg gcaggctgga gagtgtgcgc
     2221 accctcgcac cagacctgga catccgcatc ccgtatgcca cggacccggc gggcaaccgg
     2281 ctgccggacc cggagctgca cccggacagt acactcacag tgtggccgga taaccgcatc
     2341 gcggaggatg cgcactatgt ctaccgccac gatgaatacg gcaggctgac ggagaagacg
     2401 gaccgcatcc cggcgggtgt gatacggacg gacgacgagc ggacccacca ctaccactac
     2461 gacagccagc accgcctggt gttctacacg cggatacagc atggcgagcc actggtcgag
     2521 agccgctacc tctacgaccc gctgggacgg cgaatggcaa aacgggtctg gcggcgggag
     2581 cgtgacctga cggggtggat gtcgctgtcg cgtaaaccgg aggtgacgtg gtatggctgg
     2641 gacggagaca ggctgacgac ggtgcagact gacaccacac gtatccagac ggtatacgag
     2701 ccgggaagct tcacgccgct catccgggtc gagacagaga acggcgagcg ggaaaaagcg
     2761 cagcggcgca gcctggcaga gacgctccag caggaaggga gtgagaacgg ccacggcgtg
     2821 gtgttcccgg ctgaactggt gcggctgctg gacaggctgg aggaagaaat ccgggcagac
     2881 cgcgtgagca gtgaaagccg ggcgtggctt gcgcagtgcg ggctgacggt ggagcaactg
     2941 gccagacagg tggagccgga atacacaccg gcgcgaaaag ttcattttta ccactgcgac
     3001 caccggggcc tgccgctggc gctcatcagc gaagacggca atacggcgtg gcgcggggag
     3061 tatgatgaat ggggcaacca gcttaatgag gagaacccgc atcacctgca ccagccgtac
     3121 cgtctgccag ggcagcagca tgatgaggag tcggggctgt actataaccg tcaccggcac
     3181 tacgatccgt tgcaggggcg gtatatcacc ccggacccga ttgggttgag aggtggatgg
     3241 aatatgtatc agtatccgtt gaatcccata caagtgatag acccaatggg gttagatgcg
     3301 attgagaata tgacatcagg tggactaatt tatgccgtat ctggtgtacc tggattgatt
     3361 gctgcaaaca gcattactaa cagtgcttac cagttcggtt atgatatgga tgctattgtt
     3421 ggcggagctc ataatggggc cgccgatgca atgagacatt gttacttgat gtgtcgaatg
     3481 actaagacat ttggatcaac aatagctgac gtgataggta aaaatcatga ggcggcaggg
     3541 gatagacaag gtcagccagc taaagaaaga atcatggatc ttaaaaataa cactgtcggt
     3601 attgcttgtg gcgatttttc tgccaaatgt agcgatgcat gtattgaaaa atataacact
     3661 gggcaactct tcgggttaga tggtataaaa gcagataatc caataaaagc aaagcaaggg
     3721 agttcagatg cttcaaatta ttagaggcaa acttgtcatt tttttaatta ccctttgttt
     3781 atttgttgtt taccttgggt ttgataacaa ttcaaattct gacatcgtat tttatggaca
     3841 taaaacacca aagagcgttg agatatatct ttctgaaaaa aatattattt ataaaataat
     3901 taatgaccaa aaaattagta gagggaatgg tcattttata agtataatgg ttaataatta
     3961 caggacgcac tgtggagtgg ttgatataaa tcttaattt
//
LOCUS       DAPOAV010000201         3982 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.205, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000201 DAPOAV010000000
VERSION     DAPOAV010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3982
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.205"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(89..880)
                     /locus_tag="RN951_004476"
     CDS             complement(89..880)
                     /locus_tag="RN951_004476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4198 domain-containing protein"
                     /protein_id="HDX2529350.1"
                     /translation="MMKNTGYILALCLTASGHVLAHDVWITGKQAENNITAEIGYGHN
                     FPSKGTIPDRRNFFENPRIYNGKETITLKPASTDYVYKTESASKDNGYVLSTYMKPGY
                     WSRTSSGWKPVSREGRNDVAYCEFVTKYAKSFIPGEQQMPAQLYQSPTGHELEIIPLS
                     DISRFSEDVKLKVLYKTSPLAGAIMELDSVSYLKSSRHTHAVEHKHPVHKAELTFVTN
                     EDGIVTVPSLHIGQWLAKVQNKKSFQDKSLCDETVDVATLSFSRN"
     gene            complement(887..2857)
                     /locus_tag="RN951_004477"
     CDS             complement(887..2857)
                     /locus_tag="RN951_004477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001555799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent
                     hemoglobin/transferrin/lactoferrin family receptor"
                     /protein_id="HDX2529351.1"
                     /translation="MYMNVIRNVICTLIILPIGLQAETSHSSMAKDTITVVATGNQNT
                     VFETPSMVSVVTNDTPWSQNAVTSAGMLKGVAGLSQTGAGRTNGQTFNLRGYDKSGVL
                     VLVDGIRQLSDMAKSSGTYLDPALVKRIEVVRGPNSSLYGSGGLGGVVDFRTADAADF
                     LPPGETNGLSLWGNIASGDHSTGSGLTWFGKTGKTDALLSVIMRKRGNIYQSDGERAP
                     NKEKPAALFAKGSVGITDSNKAGASLRLYRNNTTEPGNPTQTHGDSGLRDRKTVQNDV
                     QFWYQYAPVDNSLINVKSTLYLSDITIKTNGHNKTAEWRNNRTSGVNVVNRSHTLIFP
                     GAHQLSYGAEYYRQQQKPEGSATLYPEGNIDFTSLYFQDEMTMKSYPVNIIVGSRYDR
                     YKSFNPRAGELKAERLSPRAAISVSPTDWLMMYGSISSAFRAPTMAEMYRDDVHFYRK
                     GKPNYWVPNLNLKPENNITREIGAGIQLDGLLTGNDRLQLKGGYFGTDARNYIATRVD
                     MKRMRSYSYNVSRARIWGWDMQGNYQSDYFDWMLSYNRTESMDASSREWLGSGNPDTL
                     ISDISIPVGHGGVSAGWRAELSAAATHVKKGDPHQAGYAVHSFSLSYKPVSVKGFEAS
                     VALDNAFNKLAMNGKGVPLSGRTVSLYTRYQW"
     gene            3139..3575
                     /locus_tag="RN951_004478"
                     /pseudo
     CDS             3139..3575
                     /locus_tag="RN951_004478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558215.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1012 a          943 c          919 g         1108 t
ORIGIN      
        1 ggcgcgtagc actgccgact gaataacaca tccccgtcaa tacggttctt gctgcacgct
       61 tacaatttca gggcagggaa tagtattgtt aatttcggga gaaacttaaa gttgccacat
      121 cgacagtttc atcacacagg cttttgtcct gaaaactttt cttattttgg actttcgcca
      181 gccactgtcc aatatgaaga gaaggtactg tgacgatacc atcctcatta gttacaaagg
      241 tgagttctgc tttatgaaca ggatgtttgt gctcaactgc atgagtatga cgggatgatt
      301 tcagataact gaccgagtca agctccatga tagctccggc gagcggggac gttttataca
      361 ggactttcag cttcacatct tcactgaaac gacttatatc ggataacgga atgatttcaa
      421 gctcatgccc cgttggagac tgatagagtt gtgctggcat ctgctgttca ccaggaataa
      481 aagatttcgc atatttagtg acaaactcac agtaagccac atcatttctg ccctcccggc
      541 tgaccggttt ccatcctgaa gaggttctcg accagtatcc cggtttcata tatgttgaca
      601 aaacgtagcc attatctttg cttgcagact cagttttata gacataatcc gtggacgctg
      661 gcttcagtgt tattgtctct ttcccgttat aaatccgggg attttcaaag aaattccttc
      721 tgtcaggaat tgtgcccttt gaggggaaat tatgaccata accaatctct gcggtaatgt
      781 tgttctctgc ctgtttacct gtaatccaga catcgtgggc caggacatgc cccgatgctg
      841 tcagacaaag agctaagata taacctgtat ttttcatcat gatttgttac cactgataac
      901 gggtataaag actgacagtt ctgcctgaaa gcggcactcc tttgccattc atggcaagct
      961 tgttgaaggc attatccaga gccactgatg cctcaaagcc tttaacactt acaggcttat
     1021 aagacagtga aaaggaatgt acggcatagc cagcctgatg gggatcgcct tttttcacat
     1081 gcgtggctgc tgccgaaagt tcagcacgcc atccggcaga aactcctcca tgaccaacag
     1141 gtatacttat gtcactgatg agtgtgtcag gattgccgga gcccagccat tccctgctgc
     1201 tggcatccat actttccgtg cggttataag aaagcatcca gtcaaaataa tcagactggt
     1261 aatttccctg catatcccat ccccagatac gggcccggga tacattataa gaataagaac
     1321 gcatccgttt catatccacg cgcgtggcaa tatagtttct ggcatccgtt ccgaaatatc
     1381 cgcctttcaa ctgcagccga tcattgcctg taagcaggcc gtccagttga atacctgcgc
     1441 caatctcacg ggtaatgtta ttttctggtt tcagattaag gttaggtacc cagtaattgg
     1501 gtttaccctt gcggtaaaaa tgtacatcat ccctgtacat ttctgccatt gtgggggcac
     1561 ggaatgcaga ggatatggag ccgtacatca tcagccagtc tgtcggtgag actgaaatcg
     1621 ccgcccttgg ggacaggcgt tcggctttca gttctccggc acggggattg aagctcttgt
     1681 accggtcata gcgggaaccg acgataatgt taaccgggta gcttttcatt gtcatttcat
     1741 cctggaaata caacgatgta aagtcaatgt ttccttccgg atatagtgtg gcagagcctt
     1801 ctggcttctg ctgctgacgg taatattcag cgccataact taactgatgg gctcccggaa
     1861 aaatcagagt atgactcctg ttgacaacat taacaccgga ggttctgttg tttctccatt
     1921 ctgccgtttt gttgtgaccg tttgtcttga tagtgatatc actgagatat aaagttgact
     1981 ttacattgat gaggctgtta tccacaggag cgtactggta ccagaactgt acgtcatttt
     2041 gtactgtttt tctgtcacgc aggccgctgt caccatgtgt ctgagtggga ttgcccggtt
     2101 cagtggtgtt attccggtag agacgcaagc tggcacctgc tttgttactg tctgttatac
     2161 cgacagagcc tttcgcaaac agggctgcag gtttttcctt gttaggtgcg cgctcaccat
     2221 cactttgata gatattacct cttttacgca taatgacaga aaggagcgca tctgtttttc
     2281 cggttttacc gaaccaggtg agccccgagc ctgtgctgtg gtcaccactg gcgatatttc
     2341 cccacagact taaaccgttt gtctctccgg ggggaaggaa atctgctgca tcggcagttc
     2401 tgaagtccac aacacctccc agcccgccac tgccgtacag actggagttt ggtccgcgga
     2461 caacttcgat acgtttgacg agtgccggat ccagataagt gccactgctt tttgccatgt
     2521 cactgagttg acggatgccg tcaacaagaa caagtacccc gcttttgtca tagccgcgta
     2581 gattaaaggt ctgcccattg gtccgtcctg caccagtctg gctgagaccg gcaacacctt
     2641 tcagcatgcc ggctgatgtg accgcattct gactccatgg cgtgtcattc gtgacgacac
     2701 tgaccattga cggcgtttca aataccgtgt tctgatttcc tgtcgcgaca acggtgattg
     2761 tatctttagc catagaagaa tgactggtct ctgcctgtaa ccctatcggg agtatgatta
     2821 atgtacaaat gacgtttctg attacgttca tatacatgcg aaaatatatg ttaatattga
     2881 tatgttataa catatcattt tattaatgca accctgatca cgcagcgttc agtgataacc
     2941 agtgaatagc gactctaata cccggtcgct ctgcaatgta tcagcgcctg cgaccgatgc
     3001 tatggatatt gatttttcta ccgataaaga accagcaata cggaatttag actggccccc
     3061 tgaatctcca gacaaccaat atcacttaaa taagtgatag tcttaatact agtttttaga
     3121 ctagtcattg gagaacagat gattgatgtc ttaggaccgg agaaacgcag acggcgtact
     3181 acacaggaaa agatcgctat tgttcagcag agctttgaac cgggaatgac ggtctccctt
     3241 gttgcccggc aacacggtgt ggcagccagc cagttatttc tctggcgcaa gcaataccag
     3301 gagggaagtc ttactgctgt ggccgcagga gaacaggtcg ttcctgcctc tgaacttgct
     3361 gctgccatga agcagattaa agaactccag cgcctgctcg gcaaaaaaac gatggaaaat
     3421 gaactcctta aagaagccgt tgaatatggg cgtgcaaaaa agtggatagc gcacgcgccc
     3481 ttattgcccg gggatgggga gtaagcttag tcagccgttg tctccgggtg tcgcgtgcgc
     3541 agttgcacgt cattctcaga cgaaccgatg actggaaata taggggcaaa tccacatcct
     3601 tacttttccg taaggatttt agcgggtcaa aacagcgttc catgccggac tgatgatcta
     3661 catacttaga gtcacatacc aaagtaaaac tatggatgta tgcaagcctg catcgtcagg
     3721 aggttaaatt tcagacctgc cagttaccgc gtaaatggct tgatatatga ctaatttatt
     3781 tgcacaggat ttttacgaca acgctctgaa ccagcagttg acgggatata tagttgagct
     3841 cattacagat aaagcttttc tgtatctctg gcggtggtca tagaccagta atcgttattg
     3901 gttgttctat attatcccgt atgacggtac aacgttttta acaactggcg ctgtcacaac
     3961 ataagccacc ccaaaatatt at
//
LOCUS       DAPOAV010000202         3927 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.206, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000202 DAPOAV010000000
VERSION     DAPOAV010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3927
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.206"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            223..615
                     /locus_tag="RN951_004479"
     CDS             223..615
                     /locus_tag="RN951_004479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529352.1"
                     /translation="MYAKSFLALDGNGRLTGARTAQAAPYAHYTCHLCGSALRYHPQY
                     ETELPWFEHTDDRLTEHGQQCPYVRPERREIQLIKRLQQFVPDALPVVRKASWHCRQC
                     HHDYYGERYCTHCQTGGFSLPRTAQQLS"
     gene            complement(625..1593)
                     /locus_tag="RN951_004480"
                     /pseudo
     CDS             complement(625..1593)
                     /locus_tag="RN951_004480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003031967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            1778..2182
                     /locus_tag="RN951_004481"
     CDS             1778..2182
                     /locus_tag="RN951_004481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001459868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HDX2529353.1"
                     /translation="MRILNCYMANDSKGHFVTAKEAAKNNRQDVLCCVSCGCPLTLKR
                     GNDGQPPWFEHDQMTVAAKILLRCTWLDPAEKEARRLHLQGMTVPDYTVKVRKWFCVM
                     CDEDYEGEKCCPRCGTGVYSRDRGAAGGQLEG"
     gene            2473..3135
                     /locus_tag="RN951_004482"
                     /pseudo
     CDS             2473..3135
                     /locus_tag="RN951_004482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368704.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            3199..3459
                     /locus_tag="RN951_004483"
                     /pseudo
     CDS             3199..3459
                     /locus_tag="RN951_004483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611998.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3469..>3927)
                     /locus_tag="RN951_004484"
     CDS             complement(3469..>3927)
                     /locus_tag="RN951_004484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004389801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDX2529354.1"
                     /translation="GHWEGDLVSGTKNSHIATLVDRKSRYTIILRLRGKDSVSVNQAL
                     TDKFLSLPSELRKSLTWDRGMELARHLEFTVSTGVKVYFCDPQSPWQRGTNENTNGLI
                     RQYFPKKTCLAQYTQHELDLVAAQLNNRPRKTLKFKTPKEIIERGVALTD"
BASE COUNT          963 a          976 c          993 g          995 t
ORIGIN      
        1 gagcatacca aagctcactg caccggtgag cgcaactttg gctgcagtcg tggctgagcc
       61 agacagacga gttatctgac ttcagtgtga tgacgtgttc acggccacca cactgatttt
      121 cccttatgag actgaactga aaccgccatt cacacctgac cacgctgccc gtaccgggac
      181 ggctgttgcc tgcgtgtcgt ctgacggtaa ggaacatata ctatgtacgc aaaatccttt
      241 ctcgctcttg atggcaacgg acgtctgacg ggcgcccgta cagcacaggc cgcaccttat
      301 gctcactaca cctgccactt gtgtggcagt gcactcagat accatccgca atacgaaact
      361 gaacttccct ggtttgaaca cactgacgac aggctgacag agcacggtca acagtgccct
      421 tatgtcaggc cggagcgcag agaaatacag ttgattaaac gtctgcagca attcgtaccg
      481 gatgccttac ccgtggtgcg taaagccagc tggcactgca gacaatgtca ccacgattat
      541 tatggggagc ggtactgcac acactgccag accggaggtt tcagtcttcc ccggacagct
      601 cagcaactgt cttgaacgta aaaattatgg agcaacgtga tggtacgatt cattccattc
      661 ttcgttcttt ctgagcattg cgttcaggat agtcagcagc ttgcgtatac aggcaaccag
      721 cgccactttt ttgggttttc ctgcggcaag cagtcgcatg taaaacacct ttattaccgg
      781 gttaaagcgg gttgcgacaa gcgctgccat gtacagggct gttcgcacac cagccctgcc
      841 gccaaagatg gttcgtcgcc ctctcatcgt gcccgagtcc cggtttactg gaaccatacc
      901 gacaagcgca ctgatttcac gcctggagag gttaccctgt tcgggtactt ccgccagcag
      961 cgcagcagcc gtcatggtgc caacaccttt aatattgctc agtcgcttag caagctcttt
     1021 gaagtggcta tggatatggc tgttcatgtc agcatctagt cgcgcaagct catcttccag
     1081 tgctttgatg atgatattaa tgcttttcct gttctatgga tgagcagggt gcaaccggtt
     1141 tctctcggca accagcatcg taatcaactg ccgcctacga actaccattg cagtgagaac
     1201 ctgacattca gtatccggca gtgctctgat aaagcgttcc cgctccggat gccggttgag
     1261 aacctcagcc atctgggaaa gcactctggc atcaatacta tcagttttcg cgaggtatcc
     1321 catggtgcgg gcaaagtcac gagcttgtct ggggttaacc acggcaagct caaaaccttc
     1381 tgcctgaagc gcacagacta tggcggtttc aagtcctcca gtggctttca ttaaaaccag
     1441 cgcaatggcg tacattctca actcagcaat gatggcctca aagccatcac tgtcattgcc
     1501 gacagaaaat tgttcaatag cgctgctggc ggcaatatcc agtatcgctt tcgaaacatc
     1561 gatacccaca caaagtgaac ctggctgact catgattacc catccttgca aatgcgttat
     1621 ggcgtactga caactgttcg ggtttcagat gagtggctca gtgtatgcgc cattcgctga
     1681 gctacgggct atgacccctt gagggatcgg gctgcataca ccttgccaaa tctaatcaca
     1741 gttattttaa ccaattgtca agatacaagg aggagatatg cgaattctga actgctatat
     1801 ggcgaatgac agcaaaggcc attttgttac ggcgaaagaa gccgcgaaga acaaccgaca
     1861 ggacgttttg tgctgtgtgt cctgtggttg tccgttaaca cttaagcggg gcaatgacgg
     1921 acaaccgccg tggtttgaac atgaccagat gactgttgct gcgaaaatcc tgctgcgatg
     1981 cacctggctt gacccggcag agaaagaggc ccgtcgtttg catctgcagg gcatgacggt
     2041 tccggattat acggtgaagg tgagaaagtg gttttgtgtg atgtgtgacg aagattatga
     2101 gggggaaaag tgctgcccgc gttgtggtac cggggtatac agcagggata ggggggctgc
     2161 aggagggcaa ctggaaggat aggaactgag cggttcagtc gcggaaatca gttgcagagc
     2221 tgtaatgata tctccgggag tgctgcgttg gtaggggcat cccgggatag agaaatttta
     2281 gcactttgcc ctgaatgatt gtagacgtcc cgagtactcg taccggcctg agttattaca
     2341 gttagatatt cgctttttct cccgcatact tcacagctgt caacgacgga tgaaaagtgg
     2401 ttcttccgca acttgggtgg aagaaaatgg atgaaacttt ctggtgaaca aagatctaag
     2461 ctgatttaag ttatgggcaa cgcaatgcac tctcttaaga cacttctaaa gttaccttgc
     2521 ggatggcgat gcagtcgaca aattattagc tctgacggta taaccctcca tctccacgga
     2581 aaacgcaaaa cagcacaatg tcctgaatgc tttaagcgta gcgactctgt tcatagttgt
     2641 cgtcggcgcc ggatacagca tctaccctgc tcagggcaga cgctatggct tgtattttcc
     2701 gtccgccact ggtactgccg taacccggct tgttcacgta aaatttttgc cgagtcgctt
     2761 gctcccttcg ccagttcaca ccagcagtct tcacaggcgt tacaaaatta acaacgtcaa
     2821 ctgggattaa tagctggagg tgaggctgga aaacgggctg caacggcagc gggtctccgt
     2881 tgcagtgctg atactcttct tcgcaggctt atcaataccc cggagacgaa acagtcaggc
     2941 gcgcctcatg tcggtattga tgagtgggcg tggcattggg gccaccgtta cggtacgtta
     3001 atattcaatc ttgatactca ccgccccctg gtcctgcttc ccggccgtga tcagcgtacg
     3061 ctggcgacct ggttcagaaa aggtccggaa atacaggttg tatcgcgtga tcgcagtgga
     3121 gtctatgcga cagctgaggt agcctgagtt taacggacac tccttcctga aatagaatgg
     3181 catcagaagg agctaataat gagcagaaaa acccaacgtt actctaaaga gttcaaagcc
     3241 gaagctgtca gaacggttct tgaaaatcaa ctttcgatca gtgaaggcgc ttcccgatta
     3301 tctcttcctg aaggcacttt aggacaatgg gttaccgccg ccagaaaagg gctcggtact
     3361 cctggttccc gcacggtggc tgaactggaa tctgaaattc tgcaactgcg taaggcgtta
     3421 aatgaagctc gccttgagcg agatatatta aaaaaagcaa ctgtagattc aatctgtcaa
     3481 tgcaacaccc ctttcaatta tctctttcgg tgttttgaac ttcagtgtct ttctcggtct
     3541 gttgtttagc tgagcagcaa ccagatctag ttcatgttga gtatattggg caagacatgt
     3601 ctttttagga aagtactgcc gaattagccc atttgtgttc tcatttgttc cccgctgcca
     3661 aggactctga ggatcgcaga agtaaacttt aacgccggtg ctgacagtaa attctagatg
     3721 tctggccagt tccattcctc tgtcccatgt cagtgatttt ctgagttctg acggtaaact
     3781 caggaatttg tcggtaagag cctgatttac tgagacagaa tctttgcccc tgagtctgag
     3841 gatgatcgta taacgtgatt ttcggtctac aagtgtggct atatgagagt tttttgtacc
     3901 tgagactaaa tcgccctccc aatgccc
//
LOCUS       DAPOAV010000203         3872 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.207, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000203 DAPOAV010000000
VERSION     DAPOAV010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3872
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.207"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..302)
                     /gene="traV"
                     /locus_tag="RN951_004485"
     CDS             complement(<1..302)
                     /gene="traV"
                     /locus_tag="RN951_004485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system lipoprotein
                     TraV"
                     /protein_id="HDX2529355.1"
                     /translation="MKQISLFIPLLGTLLLSGCAGTNTEFECNATTSDTCMTMEQANE
                     KAKKLEQSSEAKPVAASLPRLAEGNFRTMPVQTVTATTPSGSRPAVTAHPEQKLLAP"
     gene            complement(299..667)
                     /locus_tag="RN951_004486"
     CDS             complement(299..667)
                     /locus_tag="RN951_004486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001681801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbD"
                     /protein_id="HDX2529356.1"
                     /translation="MFISLMTEQTEATEIKMNMRNINVITARVVPDKNVSDDFMHAVL
                     SNCTTKIVLPAPKVFSSESLPHNFNMAAVGVMKKGMSMSLFSSPGNTVVSGHPCAGKT
                     NLTAELISAVVGSNKKGEGQ"
     gene            complement(606..1193)
                     /locus_tag="RN951_004487"
     CDS             complement(606..1193)
                     /locus_tag="RN951_004487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001438629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraP"
                     /protein_id="HDX2529357.1"
                     /translation="MPARRAEMAGDALTFRVAFVVRWLLWVVRFVVIWPLATMALMAL
                     FVLWKDNTTPGKLLVKEINFVRQTAPAGQFPVSECWFSSSDSSGRSEIQDICHYRAAD
                     AADYVRETDRSLMQLVTAFWATLALMYMSFAAGTGKYPVLPGKMKCIRVVTADEYLKD
                     VYTEDASLPGKIRKCHVYFPDDRTNRSNGDKNEHA"
     gene            complement(1162..2613)
                     /locus_tag="RN951_004488"
     CDS             complement(1162..2613)
                     /locus_tag="RN951_004488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraB"
                     /protein_id="HDX2529358.1"
                     /translation="MASINTIVKRKQYLWLGIVVVGTASAIGGALYLSDVDMSGNGET
                     VAEQEPVPDMTGVVDTTFDDKVRQHATTEMQVTAAQMQKQYEEIRRELDVLNKQRGDD
                     QRRIEKLGQDNAALAEQVKALGANPVTATGEPVPQMPAPPPGPEGEPQPGNTPVSFPP
                     QGSVAVPPPTAFYPGNGVTPPPQVTYQSVPVPNRIQRKVFTRNEGKQGPSLPYIPSGS
                     FAKAMLIEGADANASVTGNESTVPMQLRITGLVEMPNSKTYDATGCFVGLEAWGDVSS
                     ERAIVRTRNISCLKDGKTIDMPIKGHVSFRGKNGIKGEVVMRNGKILGWAWGAGFVDG
                     IGQGMERASQPAVGLGATAAYGAGDVLKMGIGGGASKAAQTLSDYYIKRAEQYHPVIP
                     IGAGNEVTVVFQDGFQLKTVEEMALEQSQSTAEEGNPESPVPNPPSAESHLNGFNTDQ
                     MLKQLGNLNPQQFMSGDKNPLGGDAGKEGGNGG"
     gene            complement(2613..3317)
                     /gene="traK"
                     /locus_tag="RN951_004489"
     CDS             complement(2613..3317)
                     /gene="traK"
                     /locus_tag="RN951_004489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system secretin
                     TraK"
                     /protein_id="HDX2529359.1"
                     /translation="MFGGLFFSCSVMAANGTLAPTVVPMVNGGQASIAISNTSPNLFT
                     VPGDRIIAVNSLDGALTNNEQTASGGVVVATVNKKPFTFILETERGLNLSIQAVPREG
                     AGRTIQLVSDLRGTGEEAGAWETSTPYESLLVTISQAVRGGKLPAGWYQVPVTKETLQ
                     APAGLSSVADSVWTGNHLKMVRFVVENKTLSALNIRESDFWQPGTRAVMFSQPASQLL
                     AGARMDVYVIRDGEGN"
     gene            complement(3328..3858)
                     /gene="traE"
                     /locus_tag="RN951_004490"
     CDS             complement(3328..3858)
                     /gene="traE"
                     /locus_tag="RN951_004490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001475328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HDX2529360.1"
                     /translation="MAIAFIFMSVLIVLSLSVNLIQGVNNYRLQNEQRTAVTPMGFNV
                     PFAVSQNSADASYLQQMALSFIALRLNVSPEIVDASHQALLQYIRPGAQNQMKVILAE
                     EAKLIKKDNVNSAFFQTSVRVWPQYGRVEIRGIRKTWIGNSEPFTDIKHYILILKREN
                     GVTWLDNFGETDDEKK"
BASE COUNT          857 a         1119 c          956 g          940 t
ORIGIN      
        1 ggtgccagca gtttctgctc cggatgtgct gtcaccgcag gtctgctgcc ggacggagtg
       61 gtcgcggtga cggtctgcac cggcattgtc cggaagttcc cttcagccag gcgcggcagt
      121 gatgccgcaa ccggctttgc ttctgaggac tgctccagtt ttttggcctt ctcattggcc
      181 tgctccatcg tcatacaggt atcggatgtg gtggcgttac actcaaattc cgtatttgtt
      241 cctgcgcagc cggaaagtaa taaggttccc agcagaggaa taaataaaga aatctgtttc
      301 attgcccttc tcctttttta ttactcccca caacagcaga aattaactct gctgtcagat
      361 ttgttttccc tgcacaggga tgtccggaga ccactgtatt tcccggagaa gaaaataagc
      421 tcatcgacat tcccttcttc atcacaccga cagcagccat attaaaattg tgcggcaatg
      481 attcagaact gaacaccttc ggagcaggaa gaactatttt tgtggtgcag ttactgagaa
      541 cagcatgcat aaaatcatct gatacgtttt tatccggcac aacgcgggct gtaataacat
      601 taatattacg catgttcatt tttatctccg ttgcttctgt ttgttcggtc atcagggaaa
      661 taaacatggc atttcctgat ttttcccggc agggaagcgt cttccgtata aacgtccttc
      721 agatattcat ctgcggttac cacccggata catttcattt ttccgggcag caccggatat
      781 ttcccggtgc ctgccgcaaa cgacatatac atcagtgcca gcgttgccca gaatgcggtg
      841 accagttgca tcagtgaccg gtcagtctcc ctgacataat ctgcagcatc agccgcgcgg
      901 taatggcaga tatcctgtat ttctgatctg cctgaagaat cagaggaaga aaaccagcat
      961 tcactgaccg ggaactgtcc ggcaggtgct gtttgtctta cgaagttaat ctccttaacc
     1021 agtaatttcc ccggcgtggt gttgtccttc cataaaacaa acagagccat cagggccatt
     1081 gtggccagcg gccagataac cacaaacctg acgacccaca gcagccagcg aacgacaaac
     1141 gccacacgga atgtcagtgc atcacccgcc atttccgccc tccttgccgg catccccgcc
     1201 cagcgggttc ttgtctccgg acataaactg ctgcggattc agattgccca gctgtttcag
     1261 catctggtcg gtgttaaaac cgttcaggtg gctttctgcc gagggaggat tcggcaccgg
     1321 gctttccggg ttaccctctt ccgctgtact ctgtgactgc tccagtgcca tttcctccac
     1381 ggttttcagc tggaagccgt cctggaacac cacggtcact tcgttgcccg caccaatcgg
     1441 tatcaccggg tgatactgtt cggcacgttt gatgtagtag tcactgagcg tctgtgcggc
     1501 tttcgatgcg ccgccaccga tacccatttt caggacatca ccagccccgt aagcggctgt
     1561 ggcacccagc ccgacagccg gttgggaggc gcgctccatt ccctgaccga taccgtcaac
     1621 aaatcccgcg ccccatgccc agccgaggat tttgccgtta cgcatcacca cttcgccctt
     1681 gataccgttt ttaccccgga agctgacatg ccccttaatc ggcatatcaa tagttttgcc
     1741 gtccttcagg caactgatat tgcgggtgcg tacaatggca cgttcactgg acacatcccc
     1801 ccaggcttcc agccccacaa aacatcccgt tgcgtcatac gtcttgctgt tcggcatttc
     1861 caccaggccg gtgatacgca actgcatcgg caccgtggat tcattaccgg tgactgaggc
     1921 attggcatcc gccccttcaa tcagcatggc tttcgcaaaa cttcctgacg gaatgtacgg
     1981 cagcgatggt ccctgttttc cctcattacg ggtaaacacc ttacgctgta tccggttagg
     2041 caccggcaca gactggtacg tcacctgtgg tggtggcgtg acaccattcc cgggataaaa
     2101 cgccgtcggc ggtggaacag caacgctgcc ctgcggcggg aaggatacgg gggtgtttcc
     2161 tggctgtggt tcgccttccg ggccgggcgg tggggcaggc atctgcggta caggctcacc
     2221 ggtcgccgtg acgggattag cacccagggc ttttacctgc tctgccaggg cggcattgtc
     2281 ctgtcccagc ttttcaatac gacgctggtc atcaccgcgc tgtttgttca gaacatccag
     2341 ctcacgacgg atttcctcat actgcttctg catctgcgct gccgtcacct gcatctctgt
     2401 ggtggcatgc tgacgcacct tgtcatcaaa ggtcgtatcc accacaccgg tcatatccgg
     2461 cacaggctcc tgttcagcca cggtttcacc gttaccggac atgtccacat cagacagata
     2521 cagtgcccca ccaatcgcgg aggctgtacc gacaaccaca atccccagcc acaggtactg
     2581 cttgcgtttc acaatggtat tgatactggc catcagttgc cctccccgtc acggatgaca
     2641 tacacatcca tgcgcgcacc tgccagtaac tggctggcag gctggctgaa catcacggca
     2701 cgggttcccg gctgccagaa atcactttcc cggatattca gggcagacag cgttttattt
     2761 tccacgacaa agcggaccat cttcaggtga ttccccgtcc atacggaatc tgccactgaa
     2821 gacagccccg ccggggcctg cagggtttcc tttgtcacag gaacctgata ccagcctgca
     2881 ggtaattttc cgccacggac agcctggctg atggtcacaa gcagggattc gtaaggcgtg
     2941 gacgtttccc acgctccggc ttcttctccg gttccgcgca ggtcactgac cagctgaatg
     3001 gtacgccccg cgccttcacg gggaacagcc tgaatggaaa ggttcagacc acgctctgtt
     3061 tccagaatga acgtaaaggg ctttttgttg acggtggcca ccaccacacc gccggaggcg
     3121 gtctgctcat tattggtcag ggcaccatcc agactgttca cggcgataat ccggtcaccg
     3181 ggaacggtaa acagattcgg gctggtattg ctgatggcaa tactggcctg accaccgttc
     3241 accattggca ccacagtggg ggccagcgta ccgtttgcgg ccatcacgct gcaggaaaaa
     3301 aacaggccgc cgaatattat tgccgtatta ttttttctca tcgtctgttt ccccgaaatt
     3361 atccagccag gtcaccccgt tttcccgctt cagaataagg atgtaatgtt tgatatcagt
     3421 aaaaggttcg gagttaccaa tccatgtttt ccgaattcca cggatttcca cacgaccata
     3481 ctgaggccag acacggacac tggtctggaa aaaagcagaa ttcacgttat cttttttaat
     3541 gagtttcgct tcttcagcca gaataacttt catctggttc tgtgcacccg ggcggatata
     3601 ttgcagaagc gcctgatgtg aagcatcgac gatttccggt gagacattca gacggagggc
     3661 aataaatgac agcgccatct gctgcaaata agaggcatcg gcactgttct gtgacacggc
     3721 aaagggcaca ttaaatccca ttggggtcac ggcagtgcgt tgctcattct gaagacggta
     3781 gttattcacc ccctgaatga ggttaacaga gaggctgaga acaataagca ctgacataaa
     3841 tataaaggcg atggccatta cacgactggt ac
//
LOCUS       DAPOAV010000204         3801 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.208, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000204 DAPOAV010000000
VERSION     DAPOAV010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3801
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.208"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..286)
                     /locus_tag="RN951_004491"
     CDS             complement(<1..286)
                     /locus_tag="RN951_004491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001405127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529361.1"
                     /translation="MEFKDLPVPFQEMASNVVRSQLATLDLSTVEKETIDNISGNVRR
                     AFIGLYEEKQLSDNQDLHEKYFLDLMDIIDKGFGLLMKKKGIRIEPLENYF"
     gene            complement(298..450)
                     /locus_tag="RN951_004492"
     CDS             complement(298..450)
                     /locus_tag="RN951_004492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1391 family protein"
                     /protein_id="HDX2529362.1"
                     /translation="MDTIELGNNESLVCGVFPNQDGTFTAMTYTRSKTFKTEAGARRW
                     LTRNTD"
     gene            complement(643..1050)
                     /locus_tag="RN951_004493"
     CDS             complement(643..1050)
                     /locus_tag="RN951_004493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX2529363.1"
                     /translation="MNEKTLGQRIRERRKQVGLSQNGLSKAAGVSGSSISLWESDHTA
                     PRGQNLHRLAEVLQCSPTWILFGDEDKTPAPPVSLDSTLDLSEDELEMLRLYRALPKS
                     EQQAQLSELRARVENFNRLFTELLEARKRNKHQ"
     gene            1128..1355
                     /locus_tag="RN951_004494"
     CDS             1128..1355
                     /locus_tag="RN951_004494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDX2529364.1"
                     /translation="MFKSDVINFYGTKAKVAKAAGVDPSAVSQWQELVPEGRAMRLQE
                     ASGGELLYDPKVYDEYRKTKRAGRLNNENHS"
     gene            1339..1860
                     /locus_tag="RN951_004495"
     CDS             1339..1860
                     /locus_tag="RN951_004495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001578395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529365.1"
                     /translation="MKITPEQAREALDAWICRPGMTQEQATILITEAFWALKERPNID
                     VQRVTDEGGAVDQRALGVNRVKIFERWKAIDTRDKREKFTALVPAIMEAIRINDFRLY
                     REISDGKSITYMIAGLNKEYGDVVESGLLFADPAVVDRETDELIEKAIAFKLAYRQQY
                     QQKAGWNYEPSFC"
     gene            1841..2806
                     /locus_tag="RN951_004496"
     CDS             1841..2806
                     /locus_tag="RN951_004496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001373617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529366.1"
                     /translation="MSLLFAERPLVINTQLAMKIGLNEAIVLQQLHYWLRDTNSGMEC
                     DGVRWIYNTTEQWLEQFPFWSESTLKRAFASLKTLGLLRCEKLNKSKRDMTNFYTINY
                     GSELLDDGKLSESIGSKCAAPSGQNDTMEEVKMKRSIGSKRPNVIGSKWPDDPTENTT
                     EITTENKNTFRPEASQPDPQTAEQDFLIRHPGAVVFSAKKRQWGSQEDLACAQWIWGR
                     IVGLYEQAASDDGEIMRPKEPNWTVWANDVRTMRMLDGRSHRQICEMFGRVQRDPFWV
                     KNIMSPSKLREKWDELVIRLGRSPVQRCVNHISEPDTEIPPGFRG"
     gene            2847..3269
                     /locus_tag="RN951_004497"
     CDS             2847..3269
                     /locus_tag="RN951_004497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF977 family protein"
                     /protein_id="HDX2529367.1"
                     /translation="MAKVFTQEEREKIKGQVVELVRQSGREMLRQLEVKTGATRYLMS
                     VLARELVASGDVYNSGYGLFPSEQARKDWQNARKKLSRAKLKEPSAVDPDLIWSLPDG
                     EIRRYDRRQNIICRECRKSEVMQRILAFYQGNARYLLK"
     gene            3522..>3801
                     /locus_tag="RN951_004498"
     CDS             3522..>3801
                     /locus_tag="RN951_004498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMEK domain-containing protein"
                     /protein_id="HDX2529368.1"
                     /translation="MIDPLIRNLQSDIALLQLYIAQRKQAGFHDMERIIESLTIFMFR
                     ALKMGELVNMNQIKVNFPAIDLADNKNMIAVQVTTNASPAKIKKTIESF"
BASE COUNT         1060 a          756 c          968 g         1017 t
ORIGIN      
        1 caaagtaatt ttcaaggggt tctattcgaa tccctttctt tttcattaac aagccaaacc
       61 ccttatcaat gatgtccatt agatccagga agtatttttc atgtaaatcc tggttatcag
      121 agagctgctt ctcttcgtac agcccgataa aggctcggcg tacgttaccg gatatattgt
      181 cgatggtttc tttttctacg gtactcaggt caagagtcgc cagttgagag cgaaccacat
      241 tcgatgccat ttcctggaat ggtactggta aatctttaaa ttccatcgtc aacctcatca
      301 gtcagtgttt ctggttaacc agcgacgcgc gccagcttca gttttaaacg ttttgcttct
      361 ggtatatgtc atcgcggtaa acgtgccgtc ctggttggga aacacgccgc ataccagaga
      421 ttcgttgttg ccaagctcga tagtatccat gctgacctca tttcccctta acgccggggt
      481 agcggaactg tttgcggaga acaccgtgcg gtgtgttgat ggaggtaatt tagttttctc
      541 attatttttc gtcaaggttt tttgatgaga aaactcaagt gttggcgcaa gataaagcca
      601 atacattgaa atgtaaggct ttaaaatttt gtgaagggat gattattgat gcttgttgcg
      661 tttgcgagcc tctaatagct cggtgaacag gcgattaaaa ttctcaacgc gggcgcggag
      721 ttcgctgagt tgtgcttgtt gctctgattt aggaagtgcg cgatacaaac gcagcatctc
      781 taactcatct tccgataagt ctagggtact atcgagtgaa acagggggag ctggtgtttt
      841 gtcctcgtcg ccaaacagta tccaggttgg tgaacattgc aatacctcgg cgaggcgatg
      901 caaattttgc ccgcgcgggg ctgtatggtc actttcccat aatgaaattg atgagccaga
      961 tacgccagca gctttgctta aaccgttttg acttaagcct acctgcttac gtctttctct
     1021 aatgcgttga cctaaagttt tctcgttcat atttagatat cttaataatc cttgacttga
     1081 gattccttga gtgattagca ttgagaaaac tcaatattgg aggtgcgatg tttaaatcag
     1141 acgtaattaa tttttacggt acgaaagcca aagtagcgaa agctgctggc gttgacccat
     1201 ctgctgtttc tcaatggcaa gagctagttc ctgaaggtcg cgcgatgcgt ctacaggagg
     1261 catctggcgg cgagcttctg tatgatccca aggtttatga cgaatatcgt aagacgaagc
     1321 gggcggggcg gttgaacaat gaaaatcact cctgaacagg ctcgtgaggc tctggatgcc
     1381 tggatatgtc gaccaggaat gacacaggag caggcgacga tattaatcac tgaagcattc
     1441 tgggctttga aagagcgccc gaacatcgat gttcagcgtg tcacagatga aggtggcgcg
     1501 gttgatcagc gagcgcttgg cgttaatcga gtgaagatat tcgaacgctg gaaggctatc
     1561 gacaccaggg ataagcgtga aaagttcacg gcgctagtgc ctgcaattat ggaggctatc
     1621 cggattaatg atttcaggtt gtatcgtgaa attagtgacg gaaaaagcat cacgtacatg
     1681 atcgccgggt taaacaaaga atatggcgat gtggtggagt ccggactgct ttttgctgat
     1741 cctgccgtag tggatcgtga aactgacgaa cttatagaaa aagcaattgc tttcaaactt
     1801 gcgtatcgac agcaatacca acaaaaagct ggatggaatt atgagccttc tttttgctga
     1861 acgcccactg gttataaaca cacagcttgc gatgaagatt ggcttaaatg aagccattgt
     1921 gttgcagcag ttgcattact ggttgagaga taccaattcc ggcatggaat gtgatggtgt
     1981 tcgctggatt tacaacacaa cggaacaatg gctggaacag ttcccattct ggtcagagtc
     2041 aacgttaaag cgcgcgtttg caagtctgaa aacgctgggg ctcttgcgtt gtgaaaagct
     2101 caataaatca aagcgcgata tgaccaattt ctacacgatt aactatggga gcgagctttt
     2161 agatgatggc aaattgagcg aatccatcgg ttcaaaatgc gccgctccat caggtcaaaa
     2221 tgacacgatg gaagaggtca aaatgaaacg ctccattggt tcaaaacgac ccaatgtcat
     2281 cgggtcaaaa tggcccgatg atcctacaga gaatacaaca gagattacta cagagaataa
     2341 aaacactttt cgtccggaag cttcgcaacc ggacccgcag acggctgaac aggatttttt
     2401 aatccggcac cctggcgcag ttgtgtttag tgcgaaaaaa cgccagtggg gtagccagga
     2461 ggatctggcg tgtgcgcagt ggatatgggg gcggatcgtg ggtctctacg aacaggccgc
     2521 cagtgatgat ggcgagatca tgcgaccaaa agagcctaac tggactgtct gggccaatga
     2581 tgtgcgcaca atgcggatgc tggatggcag aagccacaga caaatttgtg aaatgtttgg
     2641 tcgggtacag cgggatccgt tctgggtaaa aaacatcatg agcccgtcaa agctccgcga
     2701 aaaatgggac gaactggtca tccgcctggg gcgttcacct gtacagcgtt gtgttaatca
     2761 tatttctgaa ccggatacag aaattccgcc tggtttcaga ggataagttt tgatttcagg
     2821 tcatgaggta attttaaggg ggacttgtgg caaaagtttt tacacaagaa gagcgggaaa
     2881 aaattaaagg gcaggtggtg gaactcgtgc gccagagcgg tcgtgagatg ttacggcaac
     2941 tggaagtcaa gacaggtgcg acaagatatc tgatgagcgt tctcgcaaga gagctggttg
     3001 ccagcggcga tgtatacaac tctggttacg ggttattccc gtctgaacag gcgcgtaagg
     3061 actggcaaaa tgcccgtaaa aagctctcaa gggcaaagct gaaggaacca tctgcggttg
     3121 atccggacct tatctggtca ttacctgacg gagaaatacg tcgctacgac aggcgtcaga
     3181 acataatctg tcgcgagtgc cggaagagtg aagttatgca gcgcatacta gcattctatc
     3241 agggaaatgc tcgatattta ttgaagtgat gagattaaag tttattagtt cagatattga
     3301 ttggctcttt tgtggagtag ggtagagtta gtgtgtttgt ctgcttggtg ccagcagcgg
     3361 atatgtttaa caacagaaag cattcagcat ggttagtgga tttgcaaagt ggattaggat
     3421 ttgagaaact ttgatgaagt tgtaaagctt gtttctataa aaatagaaat ttaactaata
     3481 gttaaacaca cctccagctt cattgaaaag gattattagc tatgattgat ccacttatta
     3541 gaaacttaca gagtgatatt gcactactcc agctttatat cgcgcaacgc aaacaggcag
     3601 gctttcatga catggaaaga ataattgagt cattgaccat ctttatgttt cgcgcgctga
     3661 aaatgggtga actggtaaac atgaatcaga ttaaagttaa ttttcccgcc attgatttag
     3721 ctgataataa aaacatgata gcagttcaag ttactacgaa tgcaagtcca gcaaaaatta
     3781 aaaaaactat cgaatctttt g
//
LOCUS       DAPOAV010000205         3733 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.209, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000205 DAPOAV010000000
VERSION     DAPOAV010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3733
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.209"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..488
                     /locus_tag="RN951_004499"
     CDS             <1..488
                     /locus_tag="RN951_004499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6-like element IS6100 family transposase"
                     /protein_id="HDX2529369.1"
                     /translation="VDKRGDTIDFYLSPTRSAKAAKRFLGKALRGLKHWEKPATLNTD
                     KAPSYGAAITELKREGKLDRETAHRQVKYLNNVIEADHGKLKILIKPVRGFKSIPTAY
                     ATIKGFEVMRALRKGQARPWCLQPGIRGEVRLVERAFGIGPSALTEAMGMLNHHFAAA
                     A"
     gene            complement(981..1565)
                     /locus_tag="RN951_004500"
     CDS             complement(981..1565)
                     /locus_tag="RN951_004500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDX2529370.1"
                     /translation="MPRPKLKSDDEVLEAATVVLKRCGPIEFTLSGVAKEVGLSRAAL
                     IQRFTNRDTLLVRMMERGVEQVRHYLNAIPIGAGPQGLWEFLQVLVRSMNTRNDFSVN
                     YLISWYELQVPELRTLAIQRNRAVVEGIRKRLPPGAPAAAELLLHSVIAGATMQWAVD
                     PDGELADHVLAQIAAILCLMFPEHDDFQLLQAHA"
     gene            complement(1565..2803)
                     /locus_tag="RN951_004501"
     CDS             complement(1565..2803)
                     /locus_tag="RN951_004501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2529371.1"
                     /translation="MSERRYSPLATLFAATFLFRIGNAVAALALPWFVLSHTKSAAWA
                     GATAASSVIATIIGAWVGGGLVDRFGRAPVALISGVVGGVAMASIPLLDAVGALSNTG
                     LIACVVLGAAFDAPGMAAQDSELPKLGHVAGLSVERVSSLKAVIGNVAILGGPALGGA
                     AIGLLGAAPTLGLTAFCSVLAGLLGAWVLPARAARTMTTTATLSMRAGVAFLWSEPLL
                     RPLFGIVMIFVGIVGANGSVIMPALFVDAGRQVAELGLFSSMMGAGGLLGIAIHASVG
                     ARISAQNWLAVAFCGSAVGSLLLSQLPGVPVLMLLGALVGLLTGSVSPILNAAIYNRT
                     PPELLGRVLGTVSAVMLSASPMVMLAAGAFVDLAGPLPGLVVSAVFAGLVALLSLRLQ
                     FATMAAAATASAPTHTEGEH"
     gene            complement(2800..3714)
                     /locus_tag="RN951_004502"
     CDS             complement(2800..3714)
                     /locus_tag="RN951_004502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(A) family macrolide 2'-phosphotransferase"
                     /protein_id="HDX2529372.1"
                     /translation="MTVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVD
                     DGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTA
                     MVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVA
                     DDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMI
                     DWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVT
                     YALFALDSGNEEYLAAAKAQLAAAEAAE"
BASE COUNT          772 a         1198 c         1160 g          603 t
ORIGIN      
        1 cagtcgacaa gcggggcgac acgatcgatt tctacctgtc gccgacccgc agcgccaagg
       61 cagcgaagcg gttcctgggc aaggccctgc gaggcctgaa gcactgggaa aagcctgcca
      121 cgctcaatac cgacaaagcg ccgagctatg gtgcagcgat caccgaattg aagcgcgaag
      181 gaaagctgga ccgggagacg gcccaccggc aggtgaagta tctcaataac gtgatcgagg
      241 ccgatcacgg aaagctcaag atactgatca agccggtgcg cggtttcaaa tcgatcccca
      301 cggcctatgc cacgatcaag ggattcgaag tcatgcgagc cctgcgcaaa ggacaggctc
      361 gcccctggtg cctgcagccc ggcatcaggg gcgaggtgcg ccttgtggag agagcttttg
      421 gcattgggcc ctcggcgctg acggaggcca tgggcatgct caaccaccat ttcgcagcag
      481 ccgcctgatc ggcgcagagc gacagcctac ctctgactgc cgccaatctt tgcaacagag
      541 cccgccgtgc tagtctgctc ggtgatggtg gagtgaagcc aacccgcaat cgggttatga
      601 atctgcatcg cgattcgcaa tcagctgtct cttgagcatg tcgaactcct gcgatgttat
      661 ctcgccgtgc tcgtgctgct acaccaactt gtccaactca tccgccacac cgctccccac
      721 cacctgcgat ggccaggttg tttgctgggc gcattggcgg agtatcgtct cgacccggga
      781 cacccacacc ggcacaacct tacgggagtg attcactgtc aaagaatcgg cccggtgctc
      841 tgacgcaagt atcgggatgg tcaccatttg taagccgtag acctgagtgg tgatcaagac
      901 ttcgatacca ccgaccgtac cggtactaat cgacgacggt cgtgttcgtc gcctgccgca
      961 gggactctgc acacctccgt ttacgcatgt gcctggagga gttggaaatc gtcgtgttcg
     1021 ggaaacatta aacacaggat ggcagcgatc tgagccagca catgatcagc tagctcacca
     1081 tccggatcga cggcccactg catcgtcgcg ccagcgatga ccgagtgcag gagcaactca
     1141 gctgccgcag gagcacctgg gggcagtcgc ttgcggatcc cctccaccac cgcgcggttc
     1201 cgctggatcg caagcgtgcg tagctccggc acctggagct cgtaccagga gatgagatag
     1261 ttcaccgaga agtcgttgcg agtgttcatg ctccgaacga gcacctgcaa aaattcccag
     1321 agcccttgcg gccctgcgcc tatcggtatc gcattcaggt aatgccgcac ctgctcgacg
     1381 ccgcgctcca tcatcctcac cagcagcgta tcgcggttgg tgaagcgctg gattaacgct
     1441 gcgcgggaga gccccacctc ctttgctact ccgctgagcg tgaactctat gggaccgcaa
     1501 cgcttcagca ctacggtggc ggcctcgagt acctcgtcat cggacttgag cttggggcgg
     1561 ggcatcagtg ttcaccttct gtatgggttg gggcggaggc tgtggctgcc gccgccattg
     1621 tagcaaattg aagacggagc gagagtagag ccacgagccc cgcaaacacg gccgatacaa
     1681 cgaggccagg gagcggacca gcaaggtcga caaacgcgcc ggccgcaagc ataaccatgg
     1741 gcgaggctga cagcatcacc gccgagaccg tgccgagtac ccggccgaga agttctggcg
     1801 gcgtgcggtt gtagatggca gcgttgagaa tgggagagac tgagccggtc agcagtccca
     1861 cgagcgcgcc caacaacatc agcaccggca cgcctggcaa ctgtgaaagc agaagcgagc
     1921 ccaccgcaga gccacaaaat gccaccgcca gccagttctg cgctgatatc cgggcgccga
     1981 ccgacgcatg aatggcaatg ccaaggagac caccagcccc catcattgag gagaacagcc
     2041 cgagctctgc tacttggcgt cctgcatcta caaacagcgc aggcatgatg acgctgccgt
     2101 tggcgccaac gatgcccacg aagatcatca ctataccaaa gagagggcgc agcaggggtt
     2161 cgctccagag aaaagcgacg ccggcgcgca tggagagagt cgccgtcgtg gtcatcgtcc
     2221 gagcggcacg cgcgggaagc acccacgcgc cgagcagacc tgcaaggacg gagcagaacg
     2281 ccgtcagccc gagcgttggc gcagcgccaa gcaggccgat tgcggccccc ccaagggccg
     2341 ggccacctag aatcgcgacg ttcccgatca ccgctttcag tgacgagacg cgctcaacgg
     2401 agagcccggc gacgtggccg agtttgggca gctcactgtc ctgcgcggcc ataccgggtg
     2461 cgtcgaacgc ggcaccgagc accacgcaag cgatcagccc agtgttcgag agggcgccaa
     2521 cggcatcgag cagtgggatg ctcgccatgg ccacgccgcc caccacaccc gagatcaatg
     2581 cgacgggcgc gcgcccgaac cgatcgacga ggccaccacc aacccacgcg ccgatgatgg
     2641 tcgcgatgac gctgctagcg gccgtggcgc ccgcccaggc cgcgctcttt gtatgagaca
     2701 ggacgaacca tggaagcgcg agggccgcca ccgcgttgcc gatccggaag agaaaggtcg
     2761 ccgcgaacag cgtcgcgagc gggctatatc gacgttcgct cattccgctg cttccgctgc
     2821 ggcgagctgc gccttcgccg cagcgaggta ctcttcgtta cccgagtcga gggcgaagag
     2881 tgcgtaggtg accgccccga acgcaaggcg ctccgcgatg tggtgggcga gccgcggcca
     2941 cacccggcca ccggccgctt catacgtgag gaggagcttc gcgagcccct cttcaccaaa
     3001 gaccataagg tgcgcggcca tgtcgatggc agggtcatca acgcgggcct cgctccagtc
     3061 gatcatcccg ctgacgcgct ccgtgttgtc gatgagcaca tggcccacgt agagatcgcc
     3121 atgcaccacc acggagaaat ctggccacga cgaatcgtcg tcgagccagc gctgccaccg
     3181 gtggaggcgc ttgtcgttca ccacgaactc gcgtcggacg cggtcaacgt cgtcggccac
     3241 cttctgacgg gcctgcgtcg gtgtacggat gagcatcccc gcatccacgg cggcggaaat
     3301 ggggacggca tgcagggcgg cgagcgcggt cgcgaagctc tccgcgaaga cctccgagtc
     3361 ctgcggcacg acccagtcgg gcgtggacga accaggctgg atgaccatcg cagtcgagtc
     3421 ttcgagcatg ggataggcaa cgagctcggc gttggccacg cgccagtccg gcaccgcgaa
     3481 cggcaggcga ttcttgagca ttgccagcac ccgcgcctct ggttcgacct tcgcgcttac
     3541 ctcggctcgg cgcgggatgc gcagcaccca ccgacgtcca tcgtcgacgg tggcgatcac
     3601 gatcctatag tcgagcccaa gctcattgac agtcagcggg ccatggagct tgagcccatg
     3661 tcgggctgca agtgcgtaca gttgggaggt atcggcggtc gtgactacgg tcatgattca
     3721 ctcctgaggg ctt
//
LOCUS       DAPOAV010000206         3727 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.210, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000206 DAPOAV010000000
VERSION     DAPOAV010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3727
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.210"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(15..686)
                     /gene="traJ"
                     /locus_tag="RN951_004503"
     CDS             complement(15..686)
                     /gene="traJ"
                     /locus_tag="RN951_004503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001687056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer transcriptional regulator
                     TraJ"
                     /protein_id="HDX2529373.1"
                     /translation="MYPTDPRQLNTERQIYLDKQFFVDVFSIPACVRNTNGDFIGYNE
                     KFSKEFIGSLDIKEWFYSLPVQVATSFLREELDAMSLPSSMNKIQSVAIGDKLWLVQF
                     IPLIYGEVVNVLWLFFCKNSNVIVDYCRGLRTNITNDRMLEFKNKSTEIQWKVFILYS
                     FGFCHESIASLLSITNGSSRNAISEVYKFFGIHSKHDLLMIFHTSRMHSLFFDELFFI
                     LKCAE"
     gene            complement(880..1263)
                     /locus_tag="RN951_004504"
     CDS             complement(880..1263)
                     /locus_tag="RN951_004504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome protein TraM"
                     /protein_id="HDX2529374.1"
                     /translation="MARVILYISNDVYDKVNAIVEQRRQEGARDKDISVSGTASMLLE
                     LGLRVYEAQMERKESAFNQTEFNKLLLECVVKTQSSVAKILGIESLSPHVSGNPKFEY
                     ANMVEDIREKVSSEMERFFPKNDEE"
     gene            1586..2188
                     /locus_tag="RN951_004505"
     CDS             1586..2188
                     /locus_tag="RN951_004505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HDX2529375.1"
                     /translation="MVLLVVRTTNLLSLFVEWVKLFTDKVTRGGKMKKWMLAICLMFI
                     NGICEAADCFDLAGRDYKIDPDLLRAISWKESRYRVNAIGINPVTGYGSGLMQVDSQH
                     FNELARYGIKPEHLTTDPCMNIYTGAYYLAIAFKKWGVSWEAVGAYNAGFRKTERQNQ
                     RRLAYASEVYRIYTWIKSSKGIRVPTTKKSLSQINSVQKN"
     gene            complement(2485..3306)
                     /locus_tag="RN951_004506"
     CDS             complement(2485..3306)
                     /locus_tag="RN951_004506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HDX2529376.1"
                     /translation="MRLASRFGRYNSIRRERPLTDDELMQFVPSVFSGDKHESRSERY
                     TYIPTINIINKLRDEGFQPFFACQSRVRDLGRREYSKHMLRLRREGHINGKEVPEIIL
                     LNSHDGSSSYQMIPGIFRFVCTNGLVCGNNFGEIRVPHKGDIVGQVIEGAYEVLGVFD
                     KVTENMETMKEIHLNSDEQHLFGRAALMARYEDENKTPVTPEQIITPRRWEDKQNDLW
                     TTWQRVQENMIKGGLSGRSASGKNTRTRAITGIDGDIRINKALWMIAEQFREWKS"
     gene            complement(3417..3713)
                     /locus_tag="RN951_004507"
     CDS             complement(3417..3713)
                     /locus_tag="RN951_004507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001545326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529377.1"
                     /translation="MSAFSFNTTYQPTGDQQKDAIAQIGIMQNRAVQANLAYQSCRDS
                     GALFKVLHQVNNELHDLLDSLENHTPLVRKNADELIALLLLFTRQVGQSRTDLI"
BASE COUNT         1153 a          804 c          694 g         1076 t
ORIGIN      
        1 aaacgaaaca tcaactattc agcacatttt aaaataaaaa acaattcatc aaagaataaa
       61 ctatgcatcc tgcttgtatg aaaaatcatt aacaaatcat gttttgaatg tataccgaaa
      121 aacttataca cttctgaaat tgcattccgg gaagaaccat tagtaataga caaaagagat
      181 gctatcgatt catgacaaaa accaaatgaa taaagaataa aaactttcca ttggatttcc
      241 gttgatttgt ttttaaattc aagcattctg tcatttgtta tatttgtacg taatcctcta
      301 caataatcca ctatcacatt agaatttttg cagaaaaaaa gccataaaac attaaccacc
      361 tccccatata ttaatggtat aaattgtacc agccagagtt tatcacctat agccacgctc
      421 tgtattttat tcatggacga aggcaaagac atagcatcca gttcttctct taagaacgat
      481 gtagctactt gtacaggaag ggagtaaaac cactctttga tatcaagact acctataaat
      541 tctttagaga atttttcatt gtagccgata aaatctccat tagtatttcg aacacaagca
      601 gggattgaaa aaacatcgac aaaaaactgt ttatccaaat atatttgacg ttcagtatta
      661 agttgtctag gatccgtcgg atacatagga acctcctctc aaaggattct atggacagtc
      721 gatgcgggga ggtcgctctc cctgcatcgg cgatttttaa tatctgtttt aacgtggcat
      781 taaccacata attaatataa cctttatgtg gttaattgtc atcaaattga accagatcaa
      841 aatcctgtta tttgaagtaa atcaactttt aattcttttt tattcctcat cattttttgg
      901 aaaaaatcgt tccatctcag atgacacctt ctcacgaata tcttcaacca tattggcata
      961 ttcaaacttt ggattcccgg agacatgggg acttagagac tcaataccca aaattttcgc
     1021 tactgatgac tgtgttttta caacacattc aagaagaagt ttattaaact ctgtctgatt
     1081 aaacgcagac tctttacgct ccatctgagc ctcatataca cgaagcccca gttcaagaag
     1141 cattgaagct gttcccgaaa cacttatatc tttatctctt gccccctcct gacgacgctg
     1201 ttcaactatc gcatttactt tatcatagac atcattactg atatacaaaa ttactctggc
     1261 cataagataa aacctttcat tattaagcaa tgaacttttc actataaata tgcatatagt
     1321 gtttacaagt aagaaagaca ctcctagcag cgcctctagg atcatcctat aaaaaaatgc
     1381 gatccggcgc taggggcgtc cctaatatat atcaatgttt ttcatgaaaa ttgtcagtac
     1441 tgatcctaat aagagtcgct atagggtcgt aacaggatcg ccaacgactc tctatttaat
     1501 aattcagaat tattaaatat aaatagcgtt tgttaattac atgatttaaa acgtaaatca
     1561 gcaaaaactt gtttttgcgt agtgtgtggt gcttttggtg gtgagaacca ccaacctgtt
     1621 gagccttttt gtggagtggg ttaaattatt tacggataaa gtcaccagag gtggaaaaat
     1681 gaaaaaatgg atgttagcaa tctgcctgat gtttataaat gggatctgcg aagccgccga
     1741 ttgctttgat cttgcaggtc gggattacaa aatagacccg gatttactga gagcgatatc
     1801 atggaaagaa tcccgttacc gggttaatgc catcggtatt aatccggtaa cgggatatgg
     1861 cagcggactg atgcaggtag attcccagca ttttaacgaa ctggcccgct atggaattaa
     1921 gccggaacat ctgacaacag atccctgtat gaacatttat accggtgctt attatctggc
     1981 aatagccttt aaaaaatggg gcgtctcctg ggaggccgtt ggtgcataca atgccggatt
     2041 caggaagacc gaacgccaga accagagacg tcttgcctac gcatcagagg tttaccggat
     2101 ttatacctgg ataaagagca gtaaaggcat ccgggttccg accacgaaga aatcactttc
     2161 ccaaattaac agtgtgcaga aaaattaata ttgtatacat tgtcaaatac cggttatgcc
     2221 gcgacagcgg catggaaggc cacacacaaa aatatcatat gagtgataat gctgactggc
     2281 cgaagccccg caaagcggga tcccatctta tatatatccg gtaactgcgc agcctcctgc
     2341 cagaccattt ttcgcgggca caatatttac agactaccga aaagccagtt gatgaaattg
     2401 aggcatatca gacgacacag caatgccgca ggatgataat ataagtaaag ccccgaaaaa
     2461 tttttcgggg ctttacttat attatcatga cttccactcc ctgaactgtt cggcaatcat
     2521 ccataatgct ttgttgattc ggatatcacc gtcaatgcct gtaatggctc ttgttctggt
     2581 atttttaccg gaggcacttc gccccgataa tccacctttt atcatattct cctgaacccg
     2641 ctgccaggtt gtccagagat cgttctgttt atcctcccaa cggcggggag taattatttg
     2701 ttctggcgtc actggcgttt tattttcatc ttcgtacctg gccatcaatg cagctctgcc
     2761 aaataaatgt tgttcgtcac tgttaagatg tatctctttc attgtctcca tattttcagt
     2821 gactttatca aagacaccga gcacttcata cgctccctca ataacctgcc cgacaatatc
     2881 acctttatgt ggaacgcgga tttcgccaaa attattccca cacaccaggc catttgtgca
     2941 gacaaaacga aaaattcctg ggatcatctg ataactggat gaaccatcat gtgaattaag
     3001 caggataatt tcaggaactt ctttcccgtt aatatgccct tccctgcgaa gacgtaacat
     3061 atgtttactg tattcgcggc gtcccaaatc acgaacccga ctctgacagg caaagaatgg
     3121 ctggaaacct tcatcacgta acttattgat gatattgatg gttgggatat atgtataacg
     3181 ctcactccgg gattcatgtt tatcaccaga aaagacagat ggaacaaact gcattaattc
     3241 gtcatccgtt aacgggcgct cacggcgaat agaattatat cgaccaaaac gggaagctaa
     3301 tcgcataaca gtaactcctt tatgaaggca taaaattaat aaaagttttt tcgcttaata
     3361 tcatcccccc tcggttatcg ttaacaaaaa gacaacaatt ccgaggggaa ggaccatcaa
     3421 atcaggtcag ttcgggactg accaacctgc cgagtgaaaa gcagtaacag cgcgatcaac
     3481 tcatcagcgt tttttctgac aagaggagta tgattctcca ggctatccag taagtcatgc
     3541 agctcattat tgacctggtg gagcacctta aagagtgcac cagaatcccg gcagctctga
     3601 tatgcaagat ttgcctgaac agcacgattc tgcatgatcc cgatttgtgc gattgcgtct
     3661 ttctgctgat cgcctgttgg ctgataagtg gtgttaaaag aaaatgcgct cataattcct
     3721 cctgtat
//
LOCUS       DAPOAV010000207         3542 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.211, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000207 DAPOAV010000000
VERSION     DAPOAV010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3542
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.211"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            234..440
                     /locus_tag="RN951_004508"
     CDS             234..440
                     /locus_tag="RN951_004508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDX2529378.1"
                     /translation="MYIPQNFLPRSRQKLLRSAPGQSFPAVAVMPLAAKVLKKVMVNT
                     GGNKRQVPAKRQNRGSRNSKDDGG"
     gene            466..1005
                     /locus_tag="RN951_004509"
     CDS             466..1005
                     /locus_tag="RN951_004509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDX2529379.1"
                     /translation="MAVRGINKVILVGRLGKDPEVRYIPNGGAVANLQVATSETWRDK
                     QTGEMREQTEWHRVVLFGKLAEVAGEYLRKGAQVYIEGQLRTRSWEDNGITRYVTEIL
                     VKTTGTMQMLGRAAGAQTQPEEGQQFSGQPQPEPQAEAGTKKGGAKTKGRGRKAAQPE
                     PQPQPPEGDDYGFSDDIPF"
     gene            1073..1306
                     /locus_tag="RN951_004510"
     CDS             1073..1306
                     /locus_tag="RN951_004510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HDX2529380.1"
                     /translation="MSEYFRILQGLPDGPFTRKHAEAVAAQYRNVFIEDDHGEQFRLV
                     VRNNGAMVWRTWNFEDGAGYWMNHVIRDFGILK"
     gene            1334..1531
                     /locus_tag="RN951_004511"
                     /pseudo
     CDS             1334..1531
                     /locus_tag="RN951_004511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052657.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1586..2020
                     /gene="psiB"
                     /locus_tag="RN951_004512"
     CDS             1586..2020
                     /gene="psiB"
                     /locus_tag="RN951_004512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000845953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugation system SOS inhibitor PsiB"
                     /protein_id="HDX2529381.1"
                     /translation="MKTELTLNVLQTMNTQEYEDIRAAGSDERRELTHAVMREQDAPD
                     NWTMNGEYGSEFGGFFPVQVRFTPAHERFHLALCSPGDVSQVWVLVLVNAGGEPFAVV
                     QVQRRFAPEAVSHSLALAASLDAQGYSVSDIIHILMAEGSQA"
     gene            2017..2736
                     /locus_tag="RN951_004513"
     CDS             2017..2736
                     /locus_tag="RN951_004513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001763821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid SOS inhibition protein A"
                     /protein_id="HDX2529382.1"
                     /translation="MSARSQALVPLSTEQQAAWRAVAETEKRRHQGNTLAEYPYAGAF
                     FRCLNGSRRISLSDLRFFMPSLTAEELHGNRLQWLYAIDVLIETQGEVCLLPLPGDAA
                     ERLFPSVRFRVRERSRHKSALVMQKYSRQQAREAEQKARAYQALVAQAEIELAFHSPE
                     TVGSWYARWSDRVAEHDLETLFWQWGERFPSLAGMERWQWQDMPFWQVIAEAGMAARV
                     VGHAVREMERWMVPNKLREAA"
     gene            complement(2748..2936)
                     /locus_tag="RN951_004514"
     CDS             complement(2748..2936)
                     /locus_tag="RN951_004514"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="protein sok"
                     /protein_id="HDX2529383.1"
                     /translation="MKINLLRGYLLSATQHGNKPPSRHEAESLKRRAHHSPYTCTLTT
                     LTFPENNPLIQTVHGKSV"
     gene            2993..3542
                     /locus_tag="RN951_004515"
                     /pseudo
     CDS             2993..3542
                     /locus_tag="RN951_004515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611947.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS150 family transposase"
BASE COUNT          834 a          912 c         1083 g          713 t
ORIGIN      
        1 ctggcttgca gcgaccgttc cggtcgcgcc gcctctgtcg cgccgtgacc tgcgctcccg
       61 gcatcccggc aaaagaccgc gggatgtaag gggcaacgcc gtttcgcaaa ccgcgcttca
      121 cgtcgttgcg gcgggtccct gcccgttgtt ctgtccggtg ccattcacct gtttaagccc
      181 ctgtcgccgg gggcatagac agccacaacc gtctccgcca gtccaggggt gaaatgtaca
      241 tcccgcaaaa ctttttgccc agaagcaggc aaaaactttt gcggtctgcc cccggacagt
      301 cgtttccggc cgtggcagtg atgccccttg cggcgaaggt tctcaaaaag gtgatggtga
      361 ataccggagg gaacaaaagg caggtccccg caaaacgtca aaaccgcggc tcccgaaact
      421 caaaagatga tgggggctga aaacatcaac agaaggaggc acatcatggc agttcgtggc
      481 attaacaagg tcattctcgt gggacgcctg ggaaaagatc cggaagtccg ttacatcccc
      541 aacgggggcg cagtggcaaa cctgcaggtc gccacgtcgg aaacctggcg tgacaaacag
      601 acaggggaga tgcgggagca gacagaatgg catcgcgtgg tgctgttcgg caagctcgcg
      661 gaagtggctg gcgaatatct gcgcaagggc gcgcaggtct acatcgaagg tcagcttcgc
      721 acccgtagct gggaggataa cggtatcacc cgttacgtca ccgaaattct tgttaagacc
      781 acgggcacca tgcagatgct gggacgtgcc gcaggtgctc agactcagcc ggaagagggg
      841 caacagttca gcggtcagcc tcagccggaa ccacaggcgg aggccggtac gaaaaaaggt
      901 ggcgcaaaaa cgaaaggccg tggacgtaag gccgcgcagc cggagcctca gccgcaaccg
      961 ccggagggtg acgattacgg gttttcagac gatatcccgt tctgatcggg ctgactgtga
     1021 taaccgcccc gccccgcccc gttctgtgcg gggcatcacc ggagagatga ggatgagcga
     1081 atatttcaga atacttcagg ggctgcctga cggtcctttt acccgcaaac atgccgaagc
     1141 tgttgccgca cagtaccgga acgtctttat cgaggatgac cacggcgaac agtttcgcct
     1201 ggttgtccgt aataacggtg caatggtctg gcgtacctgg aattttgagg acggtgccgg
     1261 gtactggatg aaccatgtca tcagggattt cgggattctt aagtaagaga ggtgcccgac
     1321 gcgcgaacgt ccgccgcaga ttatcgcagc cctgaataag gcagggctgt ccggtgccgc
     1381 acgggacgcg gagaagatga agaaaggtga tgcggctgaa catgcagagc accatatgaa
     1441 agacaaccgc tgggttccag gctggatgtg tgcaccacgc ccacagacgg atgccactga
     1501 acgcaccgat aacctggctg atgccgcctg atgaacaacc acaccgcccc gccggagacg
     1561 gggcggcagc aagggagata ccgtgatgaa aactgaactg accctgaatg tattacagac
     1621 catgaacaca caggaatatg aagatatccg ggctgccgga agtgatgaac gccgtgagct
     1681 gactcacgcc gtgatgcggg agcaggatgc gccggataac tggacgatga acggcgagta
     1741 cggcagcgag tttggcggct ttttccccgt ccaggtccgt ttcacgcctg cccacgaacg
     1801 ttttcacctg gcgttatgtt caccgggcga tgtctctcag gtctgggtgc tggttctggt
     1861 gaatgccggt ggtgagccgt ttgcggtggt tcaggtacag cggcggtttg caccggaagc
     1921 tgtcagccat tcactggcac tggcggcgtc actggacgcg caggggtaca gcgtcagtga
     1981 catcatccat atcctgatgg cggaaggaag tcaggcatga gcgcacgttc acaggcactg
     2041 gttcctctca gcacagagca acaggccgca tggcgggcgg tggcggagac cgaaaaacgc
     2101 cgccatcagg gtaacacgct ggctgaatat ccgtatgcgg gggcgttttt ccgctgtctg
     2161 aacggaagcc gcaggatatc gctgtctgac ctgcgatttt tcatgccgtc cctgaccgca
     2221 gaagaactgc acggcaaccg tcttcagtgg ctgtatgcca tcgatgtgct gattgaaaca
     2281 cagggcgagg tttgcctcct tccccttcca ggcgatgcag cagaacgctt gttcccgtcg
     2341 gtgcggtttc gtgtcaggga acgcagtcgc cataaatccg cgctggtcat gcagaagtac
     2401 agccgccagc aggcgaggga ggcagagcag aaagcccgtg cgtaccaggc gctggtcgct
     2461 caggctgaaa tcgaactggc attccattcg ccggaaacag tcggaagctg gtatgcacgc
     2521 tggagtgacc gggtggcaga gcatgacctg gaaaccctgt tctggcagtg gggcgagcgt
     2581 tttccgtcac tggccggaat ggaacgctgg cagtggcagg atatgccatt ctggcaggtc
     2641 atcgcagagg ctggtatggc ggcaagggtg gtcggtcatg ctgttcgtga gatggagcgg
     2701 tggatggtgc cgaacaaact ccgggaggca gcgtgatgcg gcaacaatca cacggatttc
     2761 ccgtgaacgg tctgaatgag cggattattt tcagggaaag tgagtgtggt cagcgtgcag
     2821 gtatatgggc tatgatgtgc ccggcgcttg aggctttctg cctcatgacg tgaaggtggt
     2881 ttgttgccgt gttgtgtggc agaaagaaga tagccccgta gtaagttaat tttcattaac
     2941 caccatgtac tgcacccatt ttgttggacg atgaaatgga atagccccta atatgtcaaa
     3001 gccaaaatac ccttttgaaa agcgccttga agtcgtgaat cactacttca caactgatga
     3061 tggttacagg atcatctcgg cacgttttgg tgtcccccga acccaggtca ggacatgggt
     3121 tgccctctat gaaaaacatg gagaaaaagg tttaattccc aaacctaaag gcgttagtgc
     3181 tgatccagag ttgcgtatta aggtcgtgaa agctgtgatc gagcagcaca tgtcccttaa
     3241 tcaggctgct gctcacttta tgcttgctgg tagtggttct gtagccaggt ggctgaaggt
     3301 ctatgaagag cgcggagaag ctggtttacg cgcgctcaag attggcacca aaagaaacat
     3361 tgcaatatca gttgatccag aaaaagcggc atcagcattg gagctgtcaa aagaccgacg
     3421 cattgaggat cttgaaaggc aagttcgatt tcttgaaacg cggcttatgt atctaaaaaa
     3481 gctgaaagcc ttagctcatc ccacgaaaaa gtgaaagtac tcaacgagct aaggcagttt
     3541 ta
//
LOCUS       DAPOAV010000208         3512 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.213, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000208 DAPOAV010000000
VERSION     DAPOAV010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3512
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.213"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(490..1092)
                     /locus_tag="RN951_004516"
     CDS             complement(490..1092)
                     /locus_tag="RN951_004516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529384.1"
                     /translation="MKQQYQTRYEWLHESYQKWLTGFTRHAVSWGVCHPNIYYFHNLT
                     PGWVSFNGEKPEIAIVPQSLHRLIYGPDKRATPPLDDDLIVNLCTSEHLLVHHPMLEG
                     ILLSECERLRQRSLANKLISLFRQFGGTELRLKLVWLCWLDLMTGNSLEDWKENLKRK
                     SEKELEEWIINRQRQSAALTDLMDQYVLLAYRTTVDDSRN"
     gene            complement(1187..1393)
                     /locus_tag="RN951_004517"
     CDS             complement(1187..1393)
                     /locus_tag="RN951_004517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000235222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HDX2529385.1"
                     /translation="MATPVSLMDDQMVDMAFLTQLTGLTDKWFYRLIRDGAFPAPIKL
                     GRSSRWLKSEVEAWLQERIAQPRP"
     gene            1534..1800
                     /locus_tag="RN951_004518"
     CDS             1534..1800
                     /locus_tag="RN951_004518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529386.1"
                     /translation="MAEPYRYTGWLLRKDASARTRDKEGIVFVRTGREAGVLIIAELF
                     SEVVTVSQPVPGEEETDITDGIRLSDWYYKYKKSSESNVKDLPE"
     gene            2152..2277
                     /locus_tag="RN951_004519"
                     /pseudo
     CDS             2152..2277
                     /locus_tag="RN951_004519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin activation protein"
     gene            3022..>3512
                     /locus_tag="RN951_004520"
     CDS             3022..>3512
                     /locus_tag="RN951_004520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HDX2529387.1"
                     /translation="MTYKYNPFWQQRIRETVRHALNVHPRLTALRVDLRLPDVPAATD
                     AAVISRFINALKARIDAYQKRKHREGKRVHPTTLHYVWAREFGEFKGKKHYHLMLLVN
                     RDTWCRAGDYRAPESLAGMIKQAWCSALGVDVGCHATLVHFPAWPAVWLARNDDTGFQ
                     QVL"
BASE COUNT          869 a          871 c          951 g          821 t
ORIGIN      
        1 agtctgacgg atattatttc ccggtaaaac aaaccggcta ctgtaacggt taactgtatc
       61 tgcataaatt atttatgatg aaagaacagt attacggatt caaatatcat cctgtttgca
      121 ttcaggcgga cattcccgga tgccggaaag aatatcctgc aggctgagtg agtctcttcc
      181 acagtgccgg gatcgctgtc gccacgtaca tattgtcacc aggatgggta tgtaccgcag
      241 catgccattt ctggtgaata accgcacctg cacattcagt ctgctgagaa cctggcgtgt
      301 atcgggctgt aaagaacatc cctgtccgtg gctcctctgg tggtgttgcc tgctcagcaa
      361 tgacaggatg cccttaagac gcccgtcatg gctcagtatg atgacgacga acacgctctg
      421 caggtgagca tgggggccgg gagcatcatc atttccgtat tttgtcacac cttccggaag
      481 caaccggtat cagttgcggc tatcgtcaac cgttgtgcgg tatgccagga gcacgtactg
      541 atccatcaga tccgtcagtg ctgcgctctg cctctgacgg ttgatgatcc attcctccag
      601 ctctttttct gatttccgtt tcaggttctc tttccagtct tcaaggctgt ttccggtcat
      661 taaatcaagc cagcaaagcc agaccagttt gaggcgcaac tccgtgccac caaactgacg
      721 gaagaggctg atcagtttat ttgccagaga acgctgcctc agacgttcac attcagacag
      781 gagaatgcct tccagcatcg gatgatgaac cagcagatgt tcactggtgc ataaattcac
      841 tatcagatca tcatccaggg gcggcgtggc ccgtttgtca gggccataaa tcagccggtg
      901 caggctctgg ggtacgatgg caatctccgg tttttcacca ttgaatgaca cccaaccggg
      961 cgtcagatta tggaagtagt agatattcgg atgacacacg ccccaggata cggcgtgccg
     1021 ggtgaagccg gtcagccatt tctggtagct ttcgtggagc cattcgtagc gggtctgata
     1081 ctgttgtttc attttcatat tcctcacggg gatataacag gcagcagaat gccgccggca
     1141 ggccggggat tacgtctgct gcgggtgaac ggataacggt cagaaattac gggcggggct
     1201 gtgcaatacg ctcctgtagc caggcttcca cttcactttt cagccagcgg gagctgcggc
     1261 ccagcttgat gggagccgga aaggccccat ccctgatgag cctgtaaaac cacttatctg
     1321 tcaggccggt cagttgagtg agaaatgcca tgtcgaccat ctggtcatcc atcagtgaaa
     1381 ctggggtagc catgagaatg ttcctccgga tgttgttaaa ccagccggtg tggtcatgaa
     1441 aacagcgcgc caccttcacc ggcataacaa ccggggagaa acgtaaaaaa taatcgggaa
     1501 tgtgaccgcc aggagataaa cggggaggtt gcggtggctg agccgtaccg gtataccggg
     1561 tggttgttgc gaaaagatgc ttccgcacgc acgcgcgata aagaggggat agttttcgtg
     1621 aggacaggga gagaagcagg cgttctgata attgcagagt tgttttcgga ggtggttaca
     1681 gtgagtcagc ccgttcctgg cgaggaggag actgatatca ccgatgggat aaggctgtct
     1741 gattggtatt ataaatataa gaagtcatca gagagtaacg taaaggattt gccagagtaa
     1801 gctaagagag taaatctctc cggtaacaga gcgctgtgaa tcgttcatgt atcagagtgc
     1861 agatacatga acgctgatgc gtaaaatcag cagtgacacg ccagctcccc ctgtgcccat
     1921 tcctgtataa gacatgaact gagcgtatta attctcctgc cctgagactg agccggtgag
     1981 tgaggggctg agaaatccct cttgacactg ctctaaacca gaaatacttc cccggttgtt
     2041 gcggtgcgtc cggatccccg ataacggaac actaaggctg tattgcggga caccaggtaa
     2101 gtggcagccc gtaatacgcc aggagacgcg ggaaaagtga attcccacac gcgttataaa
     2161 cttacccttg cggagctgga agcctttaac tctgccgttg acaaccggct ggcagaactg
     2221 acaatgaaca aactttacga tcgcgcgccg gcttccgtct ggaaatatgt cacctgaata
     2281 ttgaagcagc gctacgatga ctccggtgtt atctgcaccg gaggaccggg aacattaagc
     2341 ggtatagcga caacaaagaa ttcgaaatca aaagggaatg gtgccggagg cgtgggcggt
     2401 aataggctga ttttcaggta ttaccggctt acaacgtgtg gttgatattg aggggctgtg
     2461 agtttcgcgt atttgtcaga aacccagatg agttttcctg tatgggacga aataaggcag
     2521 cggcaatacc tggaaaattt aatatggtat gaaggagaac ctgtcggtta cgcttaatat
     2581 acacggtaca ctgtcagctc aggggataca tgaaccgtta tctcaccagc tacacagtat
     2641 acacacactg acgctgacag tagtcagcag gaccacaata atcagcgcca gcagtatggt
     2701 aacgatacgg tctgtattcc ggtagtagcc gaaggggtcg acagaaccac aatacgggca
     2761 acacactgta ttatgagtaa tcgcgtttcc acaatccctg cacttctttt tgcgtatcac
     2821 catcactccc tcctcacagc cttacccgta accggttttt tacattaaaa aacgacgctg
     2881 aaaattcaac cgtcagtccg gagacgaccg ttcgggttat cacagagtgc ctgagacagt
     2941 gtcctgccgg aggtcacttc agggactctg cgcatttttt acgacgtggc tattccgtat
     3001 gaaccatacg gagatttaac catgacctac aaatacaacc ccttctggca gcaacgtatt
     3061 cgtgagacgg tgcggcacgc actgaatgtt catccccgcc tgacggcatt gcgggttgac
     3121 ctgcgtctcc cggatgtacc ggcagcaacg gacgcagctg tgatatcccg cttcatcaat
     3181 gccctgaaag cccgaatcga cgcttaccag aaacgtaagc atcgggaagg taaacgcgtg
     3241 catcccacca ccctgcatta cgtctgggcc cgggagtttg gggagttcaa aggtaaaaaa
     3301 cactatcacc tgatgctgct ggtcaaccgg gatacctggt gtcgtgccgg tgattaccgc
     3361 gctccggagt ctctggccgg gatgattaaa caggcgtggt gcagtgccct gggagtggat
     3421 gtcgggtgcc atgccacgct ggtgcatttt ccggcctggc cggcggtgtg gctggcgcgt
     3481 aatgatgaca ccggctttca gcaagtgctg ga
//
LOCUS       DAPOAV010000209         3469 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.214, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000209 DAPOAV010000000
VERSION     DAPOAV010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3469
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.214"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..138
                     /locus_tag="RN951_004521"
     CDS             <1..138
                     /locus_tag="RN951_004521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529388.1"
                     /translation="VKNIIPIITATLILNYLNNSERSLVKQILIEDEIIVCATYLIPD
                     I"
     gene            140..484
                     /locus_tag="RN951_004522"
     CDS             140..484
                     /locus_tag="RN951_004522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415690.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper family protein"
                     /protein_id="HDX2529389.1"
                     /translation="MKKKILAFGLISALFCSTPAMADMNRTTKGALLGAGVGLLTGNG
                     VNGVLKGAAVGAGVGAVTEKGRDGKNARKGAKVGAAVGAVTGVLTGNGLEGAIKGAVI
                     GGTGGAILGKMK"
     gene            488..823
                     /locus_tag="RN951_004523"
                     /pseudo
     CDS             488..823
                     /locus_tag="RN951_004523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707068.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YmgD family protein"
     gene            complement(880..3122)
                     /locus_tag="RN951_004524"
                     /pseudo
     CDS             complement(880..3122)
                     /locus_tag="RN951_004524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707067.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
BASE COUNT          924 a          805 c          719 g         1021 t
ORIGIN      
        1 gtaaaaaaca taattcctat catcacagcc acgctcattt tgaattatct gaataatagc
       61 gagcgttctt tagttaagca gatcttaatt gaagacgaaa ttattgtgtg tgcaacttac
      121 ttaataccgg acatctaagt tgaagaaaaa aatacttgcc ttcgggctta tctcagcatt
      181 gttctgctcc acgccagcga tggcggatat gaaccgcacc acgaaaggtg cattgctagg
      241 cgcaggcgtt ggtttactta ctggcaatgg tgttaatggc gtactgaaag gtgcagctgt
      301 tggcgctggt gttggtgcag taacagaaaa aggccgcgac ggtaaaaatg cgcgtaaagg
      361 tgcaaaagtg ggtgccgccg ttggtgctgt cactggcgtt ctgaccggca atggcctcga
      421 aggggcgatt aaaggtgccg tgattggcgg tacgggtggt gcaattctgg gtaaaatgaa
      481 ataaggaatg atgatgaaaa aatttgcttt actggcgggc ctgtttgttt tcgcaccaat
      541 gacctgggcg caggactaca atattaaaaa cggtttgccg tcagaaacct atattacttg
      601 cgcagaagcc aacgaaatgg caaaaactga cagcgcacag gttgcataaa ttgttgcggt
      661 aatgggtaat gccagcgttg ccagccgtga tttaaaaatt gagcaatctc cggaactgag
      721 cgccaaagtg gtagaaaaac tgaatcaggt ttgcgctaaa gacccgcaaa tgctgttgat
      781 cacggcaatt gatgacacca tgcgtgctat cggcaaaaaa taatatttca tatgtaccgc
      841 gtcgatgaat acgacgcggt tttttagcta acggcgggat cagaacttat atttcaggcc
      901 caccatcact gcggtgtcat tgtagccatt atcacccagc tgcacgccca cattccccag
      961 acgctggccg ctggattcag gttgccattt acgccaagtt taatttcccc caaattactc
     1021 gccccatctt gttcgacttt cacaccgttc attgagacag caaaatcttt actgttatgg
     1081 atccagttca tttcaacaaa aggttcaaag tcgtcaccgt gcggaccgct gtttttctcc
     1141 tgagtacgaa taaaggtgcg gaagccgagt cgggtctgga tgttgttatt tgcgtcattc
     1201 tcaatacgtg agccattggc ttccgtgtgc gcattatgat cgacgcccat ccagatagcc
     1261 tgtgcctgtg gctggaagat ccacgtatat ttcgccgctt ccagaccaaa ggatttattc
     1321 agggcaaaac cgtaacccgc ttccagcgag acggttgcac ctttcgcgct ataggattca
     1381 taggctaatt catccccttt caccgagttt ttaaaccagc tatattgcgc ccaggagtca
     1441 atgtatgcgc cttttttact gatgtcatcg gcaaaccagg tggcatacag ccctgcgcta
     1501 tagcctctga cactcccttt cgaacgataa tccgacacgc tggaatgagt taagttgtag
     1561 tcgcgggcat aaccagccat cactcccaaa cgccaactgt cactatcggt aaaaccaccg
     1621 gttaacagat cgccccctaa ctgcgagacg tagcgatgcg aggtcgttct caactgtccg
     1681 ttgctgtcac gccaggcatt atgcccgcca atttgacgta gccaaagtcg gcttgaacgc
     1741 tcctgttcag ttacaggatc gatgtagcgc gtttcacccg cacggtcgtt cagacgcata
     1801 acaaaaagag tgttagcagc tgccaggtta gcgacgtaac ttccagcttc ggggcgcagg
     1861 acgggggtag gcgtttctgt tgattctgaa tttccctctg agctgttatc ctcctcattc
     1921 actgactgat aacttgtcaa ataccagttt ttgccttgtt gttttagttg atattcgaaa
     1981 gctccagctg caatccttgc atcaccttat ctgaaggcat ctgctggaga ttcatcgcca
     2041 ttcacagtta tgagttcgat cccgtttagc gtggccgcgc cgcttcctcc agcatttttc
     2101 acatagacgg tagttgaacc cgaagtatta ccctcaacaa taagtctgtc cgtagccgat
     2161 ttatcatcac ctaatacggt gcggatatta agctgaccat tattaccgac ataattacct
     2221 tttacggtta atgtttttcc ttgggtaaat gtttgaccat catcatacga aagattgata
     2281 atactgtctg aattagtcag atgggtaaca acggagtcat ctttcatatt ccagattgta
     2341 ttttctgaaa gcttcagcgt ggttgtgccg ctgacgagtt tagtcgctcc atttagaata
     2401 gagtcggacg aaattatgtt taagtcacct ccagtattat taaccagaac attattacca
     2461 ggtgtgataa tacttcgatt aaggatactt acatccgttg tagttttgtt aacatcaata
     2521 ctatccaaag cacttgaaag ttcaacactt aatagtgcta ttttggcttg agaatcgata
     2581 tttgatgcat caattgatat tcctttatct tgttttgata ccgcggtgac attggaaaaa
     2641 aataactctc caccattgta tatttttgca atgggggctt tagtgcctgt tgttgtaata
     2701 gaactatttt ttatatcaat gttaccttgt cgaatagcaa ctgcataact tccatcagcc
     2761 acagtttcaa gtgccacata atctaaatta atatatgctt ttttcccatt agcataagca
     2821 ccatagctat taatgccatt agttgttatg gaaccaccat tcatttttaa atcagcacgg
     2881 ctaataactt cgtaactgtt agaatcacta acttcatcat ctacagcatc gacacatgtt
     2941 cgagactctc caggacttga acatgcaaga acacctactg cattttcccc agaggtaaca
     3001 atgttcgttt tatctgtggt ttcaagacgg gtgttattta ccatcttttc agaatcatta
     3061 acctggctta aaagtcccgc tgaatatgcc ccacccgact cgactgaatt atcaccattc
     3121 ataaagatgg tgccaccaaa ttcactgact actgcgctgg ctgttatccc tccattttct
     3181 ttgtcagata cgcttccaga ggtcttaata tcgctatcgc ttatatataa tactttgttt
     3241 tgactatcaa cagaaatacc ataagatcca tcaccactag tcatcacact ggcattattt
     3301 atatatccag ttacaccgtc atccactttc acagcatggc tttcgtcttc agtggttaga
     3361 tactctccat tacttatcgg attattatct ttgatttcaa tcggcgattc ttcatcagtc
     3421 atataggaaa ttatactata atcatccaac aattgtgttg catatgcat
//
LOCUS       DAPOAV010000210         3415 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.215, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000210 DAPOAV010000000
VERSION     DAPOAV010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3415
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.215"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(264..791)
                     /gene="mobB"
                     /locus_tag="RN951_004525"
     CDS             complement(264..791)
                     /gene="mobB"
                     /locus_tag="RN951_004525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418293.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HDX2529390.1"
                     /translation="MAGKTMIPLLAFAAWSGTGKTTLLKKLIPALCARGIRPGLIKHT
                     HHDMDVDKPGKDSYELRKAGAAQTIVASQQRWALMTETPDEEELDLQFLASRMDTSKL
                     DLILVEGFKHEEIAKIVLFRDGAGHRPEELVIDRHVIAVASDVPLNLDVALLDINDVE
                     GLADFVVEWMQKQNG"
     gene            complement(773..1357)
                     /gene="mobA"
                     /locus_tag="RN951_004526"
     CDS             complement(773..1357)
                     /gene="mobA"
                     /locus_tag="RN951_004526"
                     /EC_number="2.7.7.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase MobA"
                     /protein_id="HDX2529391.1"
                     /translation="MNLMTTITGVVLAGGKARRMGGVDKGLLELNGKPLWQHVADALM
                     TQLSHVVVNANRHQEIYQASGLKVIEDSLADYPGPLAGMLSVMQQEAGEWFLFCPCDT
                     PYIPPDLAARLNHQRKDAPVVWVHDGERDHPTIALVNRAIEPLLLEYLQAGERRVMVF
                     MRLAGGHAVDFSDHKDAFVNVNTPEELARWQEKR"
     gene            1427..1696
                     /locus_tag="RN951_004527"
     CDS             1427..1696
                     /locus_tag="RN951_004527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihD family protein"
                     /protein_id="HDX2529392.1"
                     /translation="MKCKRLNEVIELLQPAWQKEPDLNLLQFLQKLAKESGFDGELAD
                     LTDDILIYHLKMRDSAKDAVIPGLQKDYEEDFKTALLRARGVIKE"
     gene            1773..2759
                     /gene="srkA"
                     /locus_tag="RN951_004528"
     CDS             1773..2759
                     /gene="srkA"
                     /locus_tag="RN951_004528"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response kinase SrkA"
                     /protein_id="HDX2529393.1"
                     /translation="MNNSAFTFQTLHPDTIMDALFEHGIRVDSGLTPLNSYENRVYQF
                     QDEDRRRFVVKFYRPERWTADQILEEHQFALQLVNDEVPVAAPVAFNGQTLLNHQGFY
                     FAVFPSVGGRQFEADNIDQMEAVGRYLGRMHQTGRKQLFIHRPTIGLNEYLIEPRKLF
                     EDATLIPSGLKAAFLKATDELIAAVTAHWREDFTVLRLHGDCHAGNILWRDGPMFVDL
                     DDARNGPAVQDLWMLLNGDKAEQRMQLETIIEAYEEFSEFDTAEIGLIEPLRAMRLVY
                     YLAWLMRRWADPAFPKNFPWLTGEDYWLRQTATFIEQAKVLQEPPLQLTPMY"
     gene            2776..3402
                     /gene="dsbA"
                     /locus_tag="RN951_004529"
     CDS             2776..3402
                     /gene="dsbA"
                     /locus_tag="RN951_004529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA"
                     /protein_id="HDX2529394.1"
                     /translation="MKKIWLALAGLVLAFSASAAQYEDGKQYTTLEKPVAGAPQVLEF
                     FSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALG
                     VEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKA
                     AADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEKK"
BASE COUNT          861 a          823 c          847 g          884 t
ORIGIN      
        1 aaacgaaagg ctcagtcgga agactgggcc tttcgtttta tctgttgttt gtcggtgaac
       61 gctctcctga gtaggacaaa tccgccggga gcggatttga acgttgcgaa gcaacggccc
      121 ggagggtggc gggcaggacg cccgccataa actgccaggc atcaaattaa gcagaaggcc
      181 atcctgacgg atggcctttt tgcattggcg cagaaaaaaa tgccggatgc gacgctggcg
      241 cgtcttatcc agcctactct tgcttatccg ttctgctttt gcatccactc caccacaaaa
      301 tcagccagcc cctcaacatc attaatatcc agtaatgcga catcaagatt aagcggcaca
      361 tcactggcta cagcaataac atgcctgtct atcactaatt cttcaggtcg atgtccggct
      421 ccatcgcgaa acagcacaat ctttgcgatc tcttcatgct taaacccttc gaccagaatc
      481 aaatccagct ttgaggtatc cattcgactt gcgagaaact gtagatccag ctcttcttcg
      541 tctggtgttt ccgtcatcaa ggcccatcgt tgctggctgg caacgatggt ttgtgccgcg
      601 ccagccttgc gcagctcata gctatctttg cctggcttat caacatccat atcatggtgc
      661 gtatgcttaa tcagccctgg acggatccct ctggcgcata atgccgggat cagttttttc
      721 aaaagcgtag tttttccggt accactccac gcggcaaagg cgagtaacgg tatcatcgtt
      781 tttcctgcca tcgggcaagc tcctctggcg tattcacgtt aacaaatgca tctttatgat
      841 cgctgaaatc aaccgcatga ccgccagcca gacgcataaa taccattacc cggcgttctc
      901 ctgcttgcag atattccagt aataaaggct caatagcgcg gtttaccaga gcaatagtcg
      961 ggtgatcgcg ttcaccgtca tggacccaca cgacaggcgc atctttgcgc tgatgattaa
     1021 gcctggctgc taaatcaggg ggaatgtaag gcgtatcgca cgggcaaaac aaaaaccact
     1081 caccagcttc ctgctgcatt actgaaagca ttcctgccag agggcctggg taatccgcca
     1141 gtgaatcttc aatcactttc agaccgcttg cctgatagat ttcctgatga cgattagcat
     1201 taaccacgac gtgagagagc tgcgtcataa gcgcgtcagc gacatgttgc cataatggtt
     1261 tgccgtttaa ttcaagcaat cctttatcta cgccgcccat tcgtctggct ttaccgcctg
     1321 ccagcacaac gcctgttatc gtcgtcatca gattcaccga tatcgcctct tttattgtgg
     1381 gattgaccct gctaacgtgt ctgtctcaag agtaaggagc atcactatga aatgtaaacg
     1441 tctgaatgaa gttattgaac tcctccagcc agcctggcaa aaagagccag accttaacct
     1501 gctgcaattt ttgcagaaac tggcgaaaga gtcaggtttt gacggcgaac tggcggattt
     1561 gacggatgac attctgatct atcacctgaa aatgcgtgat tccgcgaaag atgcggtgat
     1621 cccgggtttg cagaaagatt atgaagaaga cttcaaaacg gcgctgttac gcgctcgcgg
     1681 cgtaattaaa gagtaaaagc ttgtaagcgg cgccaccaaa atcatcgtga aatgatatcc
     1741 ttcgtcattc gtaatgtttt ccggatgatg ggatgaataa cagcgctttt actttccaga
     1801 cactacaccc ggataccatc atggacgctc tgtttgagca tgggatccgg gtggattccg
     1861 gtcttacccc gcttaacagc tatgaaaacc gtgtctatca atttcaggac gaagatcgtc
     1921 gacgttttgt cgtcaaattt tatcgccctg aacgttggac agccgatcaa atcctcgaag
     1981 aacatcaatt tgcgttgcag ctggtaaatg atgaagttcc ggtcgcagca cctgtggcct
     2041 ttaacggtca gactttattg aatcatcagg gattttattt cgctgttttt ccaagcgtcg
     2101 gtggtcgcca gttcgaagct gataatatcg atcagatgga agcggttggg cgttatttag
     2161 ggcgtatgca ccagacgggg cgcaaacagc tttttatcca tcgcccgacc atcggtttga
     2221 acgaatatct cattgagcca cgcaagctgt ttgaggacgc tacactgata ccttccgggt
     2281 tgaaagcggc attcctgaaa gcgacagatg agctgattgc cgccgttaca gcacactggc
     2341 gggaagattt caccgttctg cggctacatg gagactgcca cgccgggaat attctctggc
     2401 gcgatggtcc aatgtttgtt gatctggatg atgcacgtaa tggtccagcc gttcaggatt
     2461 tgtggatgtt gctcaatggc gataaagccg agcagcggat gcaactggaa actattattg
     2521 aagcttatga agaatttagc gagttcgaca ccgctgaaat cggactgatt gaacctttac
     2581 gcgccatgcg tttggtttat tatcttgcct ggctaatgcg gcgttgggct gatcccgcgt
     2641 tcccgaaaaa tttcccgtgg ttaaccgggg aagattactg gctgcgacag acggcgactt
     2701 ttatagaaca ggcaaaagtt ctacaagaac cccctttgca attaacacct atgtattaat
     2761 cggagagagt agatcatgaa aaagatttgg ctggcgctgg ctggtttagt tttagcgttt
     2821 agcgcatcgg cggcgcagta tgaagatggt aaacagtaca ctaccctgga aaaaccggta
     2881 gctggcgcgc cgcaagtgct ggagtttttc tctttcttct gcccgcactg ctatcagttt
     2941 gaagaagttc tgcatatttc tgataatgtg aagaaaaaac tgccggaagg cgtgaagatg
     3001 actaaatacc acgtcaactt catgggtggt gacctgggca aagatctgac tcaggcatgg
     3061 gctgtggcga tggcgctggg cgtggaagac aaagtgactg ttccgctgtt tgaaggcgta
     3121 cagaaaaccc agaccattcg ttctgcttct gatatccgcg atgtatttat caacgcaggt
     3181 attaaaggtg aagagtacga cgcggcgtgg aacagcttcg tggtgaaatc tctggtcgct
     3241 cagcaggaaa aagctgcagc tgacgtgcaa ttgcgtggcg ttccggcgat gtttgttaac
     3301 ggtaaatatc agctgaatcc gcagggtatg gataccagca atatggatgt ttttgttcag
     3361 cagtatgctg atacagtgaa atatctgtcc gagaaaaaat aattcaatgt aaatt
//
LOCUS       DAPOAV010000211         3390 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.216, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000211 DAPOAV010000000
VERSION     DAPOAV010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3390
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.216"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            92..2005
                     /locus_tag="RN951_004530"
     CDS             92..2005
                     /locus_tag="RN951_004530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001500022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDX2529395.1"
                     /translation="MSHKTLPNLALITPYPALAAVVTEQCTGIFNCHVFHGSLEKAAG
                     IARNLDPDFYDIIISRGGTADYIDRVTKIPVVRILTSALDLLKSLTPLKKHPHKIAFF
                     NYQNYLSDVNLVATALEVEIEEFIFLSHADMVDKLKKCRTRNFQTVAGGLPVSDTAEH
                     YEMQGILIENGLESVNSALREAMAIVETTRRKQQDMARLEIILSSITEGIIVTNENNE
                     IQIFNKSAENIFGLMASQVIGKPVDTVIKNTRINQVLLTKSAEIREIMDLDNTSIITS
                     RVPIFRGTQCIGVVCSFTDTPQIQKVERIIRGKLMKKGFTARYRFEHILTQNKHMESV
                     IHLAKIYANTHSPVMIYGESGTGKELFAQSIHNQSQCHRGPFVAINCAAIPETLLESE
                     LFGYEGGSFTGARREGKEGLIELAHQGTLFLDEIGELPLPIQSRLLRVLQEYEIMRVG
                     GKDIIPVDVRIIGATNRSLEKMAEEGSFRGDLYYRLNVLPLMVPPLREREGDVRFLAE
                     HFLEKSGCGHKLAQFIALFSTYNWPGNVRELNFIIERLALLSAGFPNASLFEILNLTG
                     FNALKSCNTSQTNGRIVADLSKGQLKAVIKDLERQIIAFYMDLFEQDQEKVAAHLGIS
                     KMSLWRKYNQMDR"
     gene            2287..2952
                     /locus_tag="RN951_004531"
                     /pseudo
     CDS             2287..2952
                     /locus_tag="RN951_004531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001446451.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            3039..>3390
                     /locus_tag="RN951_004532"
     CDS             3039..>3390
                     /locus_tag="RN951_004532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDX2529396.1"
                     /translation="MVTFETVMEIKILHKQGMSSRAIARELGISRNTVKRYLQAKSEP
                     PKYTPRPAVASLLDEYRDYIRQRIADAHPYKIPATVIAREIRDQGYRGGMTILRAFIR
                     SLSVPQEQEPAVRFE"
BASE COUNT          882 a          826 c          847 g          835 t
ORIGIN      
        1 atctgagaga gaggaaaatg gctttcaatt ttgaaatcta taacagttgt gatattggtt
       61 tgtgatagcc acaaattttc catggtgatt tatgtcacat aaaacgttac ccaatctggc
      121 cttaattacc ccctatccag cactggcagc cgtagtgact gagcagtgca ccggtatttt
      181 taactgccat gtttttcacg gaagtctgga aaaagccgcg gggattgccc gtaatctcga
      241 ccctgacttc tatgacatca ttatcagccg tggcggtacg gcggactata tcgatcgcgt
      301 gaccaaaatt ccggtagtac gtattctcac gtccgcgctg gatttgctta aatcactcac
      361 gccactgaaa aaacatccgc ataaaatcgc cttttttaat tatcagaact atttatctga
      421 cgtaaatctg gtggcaaccg cgctggaagt ggagattgaa gaatttatct ttctgtcgca
      481 cgccgacatg gtcgataaac tcaaaaaatg ccgtacacgc aatttccaga cggtggcagg
      541 aggattaccg gtgtcagaca cggcggaaca ctatgagatg caaggaattc tgatcgaaaa
      601 tggtctggaa tcggtgaaca gcgcgctgcg cgaagcgatg gctatcgttg agacgacccg
      661 ccgcaagcag caggatatgg cgcgactgga gatcatcctc tcctcgatta cggaagggat
      721 catcgtcacc aatgaaaata acgagatcca gatcttcaat aaatccgccg agaacatatt
      781 tggcctgatg gcctcgcagg taattggcaa accggtagat acggttatta aaaatacgcg
      841 gattaatcag gtattgctga caaaatccgc cgaaattcgg gaaattatgg atttggacaa
      901 cacgtccatc attaccagcc gggtgccaat atttcgtggt acgcagtgta ttggggtggt
      961 gtgttcgttt accgatacgc cgcaaatcca gaaagtggaa cggattattc gcggcaaact
     1021 gatgaaaaaa ggcttcaccg cccggtaccg gtttgagcat atcctcacgc aaaataagca
     1081 catggagtcg gtgattcatc tggcaaaaat ttatgccaat acccactccc cggtgatgat
     1141 ttatggggaa tccggcaccg gtaaagagtt attcgcgcag agtattcaca accagagtca
     1201 atgccaccgt ggcccatttg tcgccattaa ctgtgccgcc attccggaaa ccctgctgga
     1261 aagcgaactg tttggctatg aagggggctc ttttaccggt gcgcggcgcg aaggaaaaga
     1321 aggcctgatt gaactggcgc accagggaac cttatttctc gatgaaattg gtgagctgcc
     1381 gctacctatt cagagccgcc tgttacgcgt cttacaggaa tacgaaatta tgcgcgtggg
     1441 gggaaaggac attatccctg tcgatgtgcg gattattggt gccactaacc gatcgctgga
     1501 aaaaatggcg gaggaaggct cgtttcgcgg cgacctctac tatcggttga acgtcttgcc
     1561 gctaatggtg cctccgctac gggaaagaga gggcgatgtc cgttttctgg ctgagcactt
     1621 cctcgaaaaa tcgggctgcg ggcataaact agcgcagttc atcgcgctgt tttccaccta
     1681 caactggccc ggaaacgtgc gtgaactgaa ttttattatt gagcgactgg cactattatc
     1741 cgccggattt cccaacgctt cgctgtttga aatattaaat ctgaccggct ttaacgcgct
     1801 aaaatcctgc aacacgtcac agacgaatgg gaggatcgtc gcggatctga gtaaaggaca
     1861 actgaaagcc gtcattaaag atcttgagcg acagattatt gccttctaca tggatctttt
     1921 tgaacaggat caagagaaag tcgccgccca tctggggatc agcaaaatga gtttatggcg
     1981 taaatacaat cagatggatc gctaagattt catctcatcg ttgctttaaa tcttccagta
     2041 tcatcggcgg attttgccgg tgtaacatca cgtggcaagc gatcgggtaa ttcattcatt
     2101 tgatgagatc catgtaatcc ggggctttgc ttgtctcatt gacaggactc cgtgaccccg
     2161 ccagtgtatc cctcctttac cgcttgatca ggccgtattt tgcgagcatc atcgcaatta
     2221 tttcccgagt aatgaaatca atgggttcca gtcaaatggg ttccagtcaa atgttgcaac
     2281 aggcaattga cgacctggcg caatggcgag cagtgcgcgc cgcataagcc attactgctg
     2341 ttatacgtac tggcgggtta tcggcaaggt catgggcgtc tgtttaatta cgcttcggaa
     2401 gatcgcgaca acctacatag tctgctggag cgatttggcc cccaacgagc ccagtaccga
     2461 ccggatatgc ctttctggcg cttacagggg gacggtttct ggcaactgca aaacgcggag
     2521 cgctgttcca catttggcag cagtcgacga cctcccgcag gtgagctggt tgagcataac
     2581 gttgctggcg gctttgataa gcaacattac gaccaactga taaaaagtaa gagcctgatt
     2641 aattccctcg cccgacaaat cctcgaagcc catttcaccg agagcattca ggaagaactc
     2701 gccgatgaac taggatttga gctcttgttg ctacgtaagc agcgcgatcc cctgttccgc
     2761 caacaggtac tgcgagccta caactacgaa tgcgccattt gcggcttcaa tatgcgccac
     2821 gacaatactt ctgtcgcgct ggaggcggcc catatcaaat ggaagcagta cggtggccct
     2881 tgcgaaattc ctaatggtct ggccctctgc gcaattcatc ataaagcttt tgataaggga
     2941 tccattggtt tatgtcacga acggtgcaat agtgatccac acccaacgcc tgaaatcaga
     3001 tccagggggt aatctgctct cctgattcag gagagcttat ggtcactttt gagacagtta
     3061 tggaaattaa aatcctgcac aagcagggaa tgagtagccg ggcgattgcc agagaactgg
     3121 ggatctcccg caataccgtt aaacgttatt tgcaggcaaa atctgagccg ccaaaatata
     3181 cgccgcgacc tgctgttgct tcactcctgg atgaataccg ggattatatt cgtcaacgca
     3241 tcgccgatgc tcatccttac aaaatcccgg caacggtaat cgctcgcgag atcagagacc
     3301 agggatatcg tggcggaatg accattctca gggcattcat tcgttctctc tcggttcctc
     3361 aggagcagga gcctgccgtt cggttcgaaa
//
LOCUS       DAPOAV010000212         3381 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.217, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000212 DAPOAV010000000
VERSION     DAPOAV010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3381
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.217"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            338..1654
                     /gene="shiA"
                     /locus_tag="RN951_004533"
     CDS             338..1654
                     /gene="shiA"
                     /locus_tag="RN951_004533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate transporter"
                     /protein_id="HDX2529397.1"
                     /translation="MDSTLISTRPDERTVSLSRARRAALGSFAGAVVDWYDFLLYGIT
                     AALVFNREFFPQVSPAMGTLAAFATFGVGFLFRPLGGVIFGHFGDRLGRKRMLMLTVW
                     MMGIATALIGILPSFSTIGWWAPILLVTLRAIQGFAVGGEWGGAALLSVESAPKNKKA
                     FYSSGVQVGYGVGLLLSTGLVSLISMMTTDEQFLSWGWRIPFLFSIVLVLGALWVRNG
                     MEESAEFEQQQHYQAAAKKRIPVIEALLRHPGAFLKIIALRLCELLTMYIVTAFALNY
                     STQNMGLPRELFLNIGLLVGGLSCLTIPCFAWLADRFGRRRVYITGALIGTLSAFPFF
                     MALEAQSIFWIVFFSIMLANIAHDMVVCVQQPMFTEMFGASYRYSGAGVGYQVASVVG
                     GGFTPFIAAALITYFAGNWHSVAIYLLAGCLISAMTALLMKDNHRA"
     gene            1756..3210
                     /gene="amn"
                     /locus_tag="RN951_004534"
     CDS             1756..3210
                     /gene="amn"
                     /locus_tag="RN951_004534"
                     /EC_number="3.2.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP nucleosidase"
                     /protein_id="HDX2529398.1"
                     /translation="MNNKGSGLTPAQALDKLDALYEQSVVALRNAIGNYITSGELPDE
                     NARKQGLFVYPSLTVTWDGSTTNPPKTRAFGRFTHAGSYTTTITRPTLFRSYLNEQLT
                     LLYQDYGAHISVQPSQHEIPYPYVIDGSELTLDRSMSAGLTRYFPTTELAQIGDETAD
                     GIYHPTEFSPLSHFDARRVDFSLARLRHYTGTPVEHFQPFVLFTNYTRYVDEFVRWGC
                     SQILDPDSPYIALSCAGGNWITAETEAPEEAISDLAWKKHQMPAWHLITANGQGITLV
                     NIGVGPSNAKTICDHLAVLRPDVWLMIGHCGGLRESQAIGDYVLAHAYLRDDHVLDAV
                     LPPDIPIPSIAEVQRALYDATKLVSGRPGEEVKQRLRTGTVVTTDDRNWELRYSASAL
                     RFNLSRAVAIDMESATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANRFYEGAIS
                     EHLQIGIRAIDLLRAEGDRLHSRKLRTFNEPPFR"
BASE COUNT          783 a          832 c          811 g          955 t
ORIGIN      
        1 ctcaacaatg atgctaaaaa catacctaac ctcgcctccc tactggttat aatgcaatgc
       61 agtctatcag actcatcagg gtgccatttt gtgcatatgc ggacttttat gtttcatatc
      121 tctaacctgt gggtcctctg cttaatcctt aaacaacacc agcaactcct gcgctttcat
      181 cttccatcga atttttcatg ttgccgctaa tcagccataa aatcatttgc agatgcgctc
      241 tgtcgaggta gtctcataag gttcgtttat agatcgacgg caatgtgagt taccttttcc
      301 atactaatta taaaaagaca gtacaaacag gatcattatg gactccacgc tcatctccac
      361 tcgtcccgat gaaaggacgg tttcgttaag tcgcgcccga cgagctgcgt taggcagctt
      421 cgctggtgcc gtcgtcgact ggtatgattt tttactctat ggcatcaccg ccgcactggt
      481 gtttaatcgc gagtttttcc cgcaagtaag cccggcgatg ggaacgctcg ccgcatttgc
      541 cacctttggc gtcggattcc ttttccgtcc gctcggcggt gtcattttcg gtcactttgg
      601 cgaccggctg ggacgtaagc gcatgttaat gctgaccgtc tggatgatgg gcatcgcgac
      661 agccttgatt ggtattcttc cttcattctc gaccattggg tggtgggcac ctattttgct
      721 ggtgacactg cgtgccattc agggatttgc cgtcggcggc gaatggggag gcgcggcgtt
      781 gctttccgtt gaaagtgcac cgaaaaataa aaaagccttt tacagtagcg gtgtacaagt
      841 tggctacggt gtaggtttac tgctttcaac cggactggtt tcattgatca gtatgatgac
      901 gactgacgaa cagtttttaa gctggggctg gcgcattcct ttcctgttta gcatcgtact
      961 ggtactggga gcattgtggg tgcgcaatgg catggaggag tccgcggaat ttgaacaaca
     1021 gcaacattat caagctgccg cgaaaaaacg catcccggtt atcgaagcgc tgttacgaca
     1081 tcccggtgct ttcctgaaga ttattgcgct acgactgtgc gaattgctga cgatgtacat
     1141 cgttactgcc tttgcactta attattcaac ccagaatatg gggttaccgc gcgaactttt
     1201 cctcaatatt ggtttgctgg taggtggatt aagctgcctg acaattccct gttttgcctg
     1261 gcttgccgat cgttttggtc gccgcagggt ttatatcaca ggtgcgttaa tcggaacgtt
     1321 gagcgcattt cctttcttta tggcgcttga agcacaatct attttctgga tagttttctt
     1381 ctccataatg ctggcaaaca ttgcgcatga catggtggtg tgtgtgcaac aaccgatgtt
     1441 taccgaaatg tttggtgcca gttatcgcta tagtggtgct ggagtcggtt atcaggtcgc
     1501 cagtgtggtt ggcggtggat ttacaccttt tattgccgct gcgctcatca cttactttgc
     1561 cgggaactgg catagcgtcg ccatttattt gctggctgga tgtctgattt ccgcaatgac
     1621 cgctttgttg atgaaagaca atcaccgcgc ttgatagcct ggcgaagatc atccgatctt
     1681 cgccttacac ttttgtttca cattcctgtg acatactatc ggatgtgcgg taattgtatg
     1741 gaacaggaga cacacatgaa taataagggc tccggtctga ccccagctca ggcactggat
     1801 aaactcgacg cgctgtatga gcaatctgta gtcgcattac gcaacgccat tggcaactat
     1861 attacaagtg gcgaattacc tgatgaaaac gcccgcaaac aaggtctttt tgtctatcca
     1921 tcactgaccg taacctggga cggtagcaca accaatcccc ccaaaacgcg cgcatttggt
     1981 cgttttactc acgcaggcag ctacaccacc acgattactc gccctactct ctttcgttcg
     2041 tatctcaatg aacaacttac gttgctgtat caggattatg gtgcgcatat ctcggtgcaa
     2101 ccctcgcagc atgaaatccc ctatccttat gtcatcgatg gctctgaatt gacacttgat
     2161 cgctcaatga gcgctgggtt aactcgctac ttcccgacaa cagaactggc gcaaattggc
     2221 gatgaaactg cagacggcat ttatcatcca actgaattct ccccgctatc gcattttgat
     2281 gcgcgccgcg tcgatttttc cctcgcgcgg ttgcgccatt ataccggtac gccagttgaa
     2341 cattttcagc cgttcgtctt gtttaccaac tacacacgtt atgtggatga attcgttcgt
     2401 tggggatgca gccagatcct cgatcctgat agtccctaca ttgccctttc ttgtgctggc
     2461 gggaactgga tcaccgccga aaccgaagcg ccagaagaag ccatttccga ccttgcatgg
     2521 aaaaaacatc agatgccagc atggcattta attaccgcca atggtcaggg tattactctg
     2581 gtgaatattg gcgtgggacc gtcaaatgct aaaaccatct gcgatcatct ggcagtgcta
     2641 cgcccggatg tctggttgat gattggtcac tgtggcggat tacgtgaaag tcaggccatt
     2701 ggcgattatg tacttgcaca cgcttattta cgcgatgacc acgttcttga tgcggttctg
     2761 ccgcccgata ttcctattcc gagcattgct gaagtgcaac gtgcgcttta tgacgccacc
     2821 aagctggtga gcggcaggcc cggtgaggaa gtcaaacagc ggctacgtac tggtactgtg
     2881 gtaaccacag atgacaggaa ctgggaatta cgttactcag cttctgcact tcgttttaac
     2941 ttaagccggg ccgtagcaat tgatatggaa agtgcaacca ttgccgcgca aggatatcgt
     3001 ttccgcgtgc catacgggac actactgtgt gtttcagata aaccgttgca tggcgagatt
     3061 aaacttcccg gccaggctaa ccgtttttat gaaggcgcta tttccgaaca tctgcaaatt
     3121 ggcattcggg cgatcgattt gctgcgcgca gaaggcgacc gactgcattc gcgtaaatta
     3181 cgaaccttta atgagccgcc gttccgataa taagttatga accttcttat cagaaataga
     3241 tgtgaaggat taagtaagac atctggcaaa tagcctgcaa taaacgcggg ctgtttgctt
     3301 ccttgggcag atgcgagttt tattatcatc ttaatgattt ccacatatta aaagcaagta
     3361 tgctttcaaa acacaattat a
//
LOCUS       DAPOAV010000213         3313 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.218, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000213 DAPOAV010000000
VERSION     DAPOAV010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3313
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.218"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..1202
                     /locus_tag="RN951_004535"
     CDS             <1..1202
                     /locus_tag="RN951_004535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310137.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDX2529399.1"
                     /translation="RYSTQGFYNLSDSAYSRMSGYTVKPPTGDTNEQTQFIDYFNLFY
                     SKRGQEQISISQQLGNYGTTFFSASRQSYWNTSRSDQQISFGLNVPFGDITTSLNYSY
                     SNNIWQNDRDHLLAFTLNVPFSHWMRTDSQSAFRNSNASYSMSNDLKGGMTNLSGVYG
                     TLLPDNNLNYSVQVGNTHGGNTSSGTSGYSSLNYRGAYGNTNVGYSRSGDSSQIYYGM
                     SGGIIAHADGITFGQPLGDTMVLVKAPGADNVKIENQTGIHTDWRGYAILPFATEYRE
                     NRVALNANSLADNVELDETVVTVIPTHGAIARATFNAQIGGKVLMTLKYGNKSVPFGA
                     IVTHGENKNGSIVAENGQVYLTGLPQSGQLQVSWGKDKNSNCIVEYKLPEVSPGTLLN
                     QQTAICR"
     gene            1216..1746
                     /locus_tag="RN951_004536"
     CDS             1216..1746
                     /locus_tag="RN951_004536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDX2529400.1"
                     /translation="MKYNNIIFLGLCLGLTTYSALSADSVIKISGRVLDYGCTVSSDS
                     LNFTVDLQKNSARQFPTTGSTSPAVPFQITLSECSKGTTGVRVAFNGIEDAENNTLLK
                     LDEGSNTASGLGIEILDANMRPVKLNDLHAGMQWIPLVPEQNNILPYSARLKSTQKSV
                     NPGLVRASATFTLEFQ"
     gene            1759..2262
                     /locus_tag="RN951_004537"
     CDS             1759..2262
                     /locus_tag="RN951_004537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDX2529401.1"
                     /translation="MKRLHKRFLLATFCALFTATLQAADVTITVNGRVVAKPCTIQTK
                     EANVNLGDLYTRNLQQPGSASGWHNITLSLTDCPVETSAVTAIVTGSTDNTGYYKNEG
                     TAENIQIELRDDQDAALKNGDSKTVIVDEITRNAQFPLKARAITVNGNASQGTIEALI
                     NVIYTWQ"
     gene            2321..3235
                     /locus_tag="RN951_004538"
     CDS             2321..3235
                     /locus_tag="RN951_004538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX2529402.1"
                     /translation="MGKTISIKVLFGIYLLLMAGKVFAFSCNVDGGSSIGAGTTSVYV
                     NLDPVIQPGQNLVVDLSQHISCWNDYGGWYDTDHINLVQGSAFAGSLQSYKGSLYWNN
                     VTYPFPLKTNTNVLDIGDKTPMPLPLKLYITPVGAAGGVVIKAGEVIARIHMYKIATL
                     GSGNPRNFTWNIISNNNVVMPTGGCTVDSRNVTVDLPDFPGSAEIPLGVYCSSEQKLS
                     FYLSGATTDSSRQVFANTAPDATKASGVGVTLMRNGKILATGENVSLGTVNKSKVPLG
                     LSATYGQTGNKVSAGTVQSVIGVTFIYE"
BASE COUNT          952 a          704 c          758 g          899 t
ORIGIN      
        1 atcgctattc tacgcaaggt ttttataact tatccgacag tgcctacagt cgaatgagtg
       61 gttacaccgt caagcctcct accggagaca ccaatgagca gacacaattt attgattatt
      121 ttaatctgtt ctacagtaag cgtggtcagg aacaaataag catctctcag cagcttggaa
      181 attacggtac gacatttttc agtgccagtc gccaaagtta ctggaacacg tcacgcagcg
      241 accagcaaat atcatttgga ttaaatgtgc cgtttggtga tattacgact tcgctgaatt
      301 acagctattc caataatata tggcaaaacg atcgggatca tttactcgct tttacgctta
      361 atgttccctt cagtcattgg atgcgtacag acagtcagtc ggcatttcgt aattcaaacg
      421 ccagttacag tatgtcaaac gatttgaaag gcggcatgac caatctatcg ggggtttatg
      481 gcactctgct gccggataat aacctgaatt atagcgttca ggtcggtaac acccacggag
      541 gtaatacatc gtctggcacc agtggttaca gttctcttaa ttatcgtgga gcttatggta
      601 atactaatgt cggttacagt cggagtggtg acagcagcca gatttattac ggaatgagtg
      661 gtgggattat tgctcatgct gatggcatca cctttggaca gccgctgggc gacacaatgg
      721 ttctggttaa ggctcctggt gctgataatg tcaaaataga gaaccagacc ggaattcata
      781 ccgactggcg tggctatgcc atattaccat ttgcgacaga atatagagaa aaccgtgttg
      841 ctcttaacgc gaattccctt gcagataatg ttgaactgga tgaaaccgtg gtcactgtca
      901 tcccaactca cggtgctatt gccagagcaa catttaatgc acaaatcggc gggaaagtat
      961 taatgacgtt gaagtacggt aataagagcg ttccattcgg tgcaattgtc acacacggag
     1021 agaataaaaa tggcagcatt gtcgcggaaa atggtcaggt ttatctgact ggacttccac
     1081 agtcagggca attacaggtt tcatggggca aagataaaaa ctcaaactgt attgtcgagt
     1141 acaagcttcc tgaagtttct cctggtacct tactgaacca gcagacagca atctgtcgct
     1201 aaggaacaat agattatgaa atacaataac attattttcc tcggtttatg tctggggtta
     1261 accacctatt ctgctttatc cgcagatagc gttattaaaa ttagcgggcg cgtcctcgat
     1321 tatggctgca cagtctcatc ggattcgctt aattttaccg tagatctcca aaaaaacagt
     1381 gccagacaat ttccaacgac cggtagcaca agtccagccg tcccttttca gattacgtta
     1441 agtgaatgca gcaaagggac aacgggggtt cgggttgcat ttaacggtat tgaggatgca
     1501 gaaaataata ctttgttgaa actggatgaa ggaagcaata cggcctccgg tttgggtata
     1561 gaaatattgg acgcaaatat gcgtccggtg aaactgaatg atcttcatgc cgggatgcag
     1621 tggatcccac tggtaccaga acagaacaat attttgcctt actccgctcg tctgaagtca
     1681 actcagaagt ccgtcaatcc gggactggtg agggcttcgg caacctttac ccttgaattt
     1741 caataatcag agtcagatat gaaaagactt cacaagaggt tcctgttagc tacgttttgc
     1801 gcgttattca cagcaactct ccaggccgcc gatgtcacta tcactgttaa tggtcgggta
     1861 gtcgctaaac cctgcactat tcaaaccaaa gaagctaacg ttaatctcgg ggatctttat
     1921 acgcgcaatc tgcaacaacc tggttctgca tctggctggc acaatattac tttgtcatta
     1981 accgattgtc cggttgaaac aagtgcagtg acggcaatcg tgacaggttc aactgacaat
     2041 acgggttatt acaaaaatga aggtactgcc gaaaatattc agatagagct gagggatgac
     2101 caggatgctg cgttaaaaaa tggcgatagc aaaacggtta ttgttgatga gatcactcgt
     2161 aatgcacagt ttccacttaa ggcaagagct atcacggtga atggaaacgc aagccaggga
     2221 acgatcgagg cgctaatcaa tgtgatctac acctggcaat aacgtcgatt cgattttctt
     2281 agccttcttt ttaaatcaat ttttaacctt aggatatatc atgggtaaaa caatcagtat
     2341 aaaggtcctg ttcggtattt atcttctatt aatggcaggc aaagtttttg ccttcagttg
     2401 taatgtcgat ggcgggtcaa gtattggagc aggtacaacc tctgtttatg ttaatctcga
     2461 ccctgtaata cagccgggcc agaatctggt tgtagacttg tctcagcata taagttgctg
     2521 gaatgattac ggcggctggt acgacactga tcatataaac ctggtacaag gctcagcttt
     2581 cgcaggctcc ctacagtcat ataaaggatc gctgtactgg aataatgtga cctacccctt
     2641 cccgttgaag acaaatacca acgtattgga tattggtgat aagacaccga tgccattacc
     2701 gttaaaactc tatattaccc cagttggggc ggccggtgga gttgtcataa aagcggggga
     2761 agtcattgcc cgtattcata tgtataaaat tgcaacatta ggaagcggaa atccgcgtaa
     2821 ttttacgtgg aatattattt caaataacaa tgttgttatg ccaacaggcg gctgcaccgt
     2881 tgatagtcgt aatgtcaccg tggatctccc ggactttcct ggaagcgcag aaatacccct
     2941 tggcgtatat tgctcaagcg aacaaaagct ctcattttat ctttcgggtg ccaccactga
     3001 cagtagccga caagtgtttg ctaacacagc acctgatgca acaaaagcat cgggagtggg
     3061 tgtcactcta atgcgtaatg gaaaaatact ggctacggga gaaaatgtct ccctggggac
     3121 agtaaataaa agcaaagtac ctctgggttt aagcgcaacc tatggacaaa caggaaacaa
     3181 ggtttcagcc ggaaccgtcc agtcagtcat tggtgtcact tttatctatg aataattgtg
     3241 attttgacct tagtctatgc gctccattca cgaaaattgc gcggataatt attttgtgaa
     3301 ggctattagc cta
//
LOCUS       DAPOAV010000214         3272 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.219, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000214 DAPOAV010000000
VERSION     DAPOAV010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3272
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.219"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            180..1715
                     /gene="gadC"
                     /locus_tag="RN951_004539"
     CDS             180..1715
                     /gene="gadC"
                     /locus_tag="RN951_004539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance gamma-aminobutyrate antiporter
                     GadC"
                     /protein_id="HDX2529403.1"
                     /translation="MATSVQTGKAKQLTLLGFFAITASMVMAVYEYPTFATSGFSLVF
                     FLLLGGILWFIPVGLCAAEMATVDGWEEGGVFAWVSNTLGPRWGFAAISFGYLQIAIG
                     FIPMLYFVLGALSYILKWPALNEDPITKTIAALIILWALALTQFGGTKYTARIAKVGF
                     FAGILLPAFILIALAAIYLHSGAPVAIEMDSKTFFPDFSKVGTLVVFVAFILSYMGVE
                     ASATHVNEMSNPGRDYPLAMLLLMVAAICLSSVGGLSIAMVIPGNEINLSAGVMQTFT
                     VLMSHVAPEIEWTVRVISALLLLGVLAEIASWIVGPSRGMYVTAQKNLLPAAFAKMNK
                     NGVPVTLVISQLVITSIALIILTNTGGGNNMSFLIALALTVVIYLCAYFMLFIGYIVL
                     VLKHPDLKRTFNIPGGKGVKLVVAIVGLLTSIMAFIVSFLPPDNIQGDSTDMYVELLV
                     VSFLVVLALPFILYAVHDRKGKANTGVTLEPINSQNAPKGHFFLHPRARSPHYIVMND
                     KKH"
     gene            1846..3165
                     /locus_tag="RN951_004540"
     CDS             1846..3165
                     /locus_tag="RN951_004540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 10 protein"
                     /protein_id="HDX2529404.1"
                     /translation="MDICSRNKKLTIRRPAILVALALLLCSCKSTPPESMVTPPAGSK
                     PPATTQQSSQPMRGIWLATVSRLDWPPVSSVNISNPTSRARVQQQAMIDKLDHLQRLG
                     INTVFFQVKPDGTALWPSKILPWSDLMTGKIGENPGYDPLQFMLDEAHKRGMKVHAWF
                     NPYRVSVNTKPGTIRELNSTLSQQPASVYVQHRDWIRTSGDRFVLDPGIPEVQDWITS
                     IVAEVVSRYPVDGVQFDDYFYTESPGSRLNDNETYRKYGGAFASKADWRRNNTQQLIA
                     KVSHTIKSIKPGVEFGVSPAGVWRNRSHDPLGSDTRGAAAYDESYADTRRWVEQGLLD
                     YIAPQIYWPFSRSAARYDVLAKWWADVVKPTRTRLYIGIAFYKVGEPSKIEPDWMING
                     GVPELKKQLDLNDAVPEISGTILFREDYLNKPQTQQAVSYLQSRWGS"
BASE COUNT          799 a          815 c          796 g          862 t
ORIGIN      
        1 cagaacagct ttaaacatac ctgataacgt ttaacggtaa cggtgtcccg aaacgaaccc
       61 gtttcgggac aatttccaaa gtctgttcac tggcattagc aacggaaaat attgttctga
      121 atacgcttca gaacaaaaca ggtgcggttc cgacaggaat accgttttag ggggataata
      181 tggctacatc agtacagaca ggtaaagcta agcagctcac attacttgga ttctttgcca
      241 taacggcatc gatggtaatg gctgtttatg aataccctac cttcgcaaca tcgggctttt
      301 cattagtctt cttcctgcta ttaggcggga ttttatggtt tattcccgtg ggactttgtg
      361 ctgcggaaat ggccaccgtc gacggctggg aagaaggtgg tgtcttcgcc tgggtatcaa
      421 atactctggg gccgagatgg ggatttgcag cgatctcatt tggctatctg caaatcgcca
      481 ttggttttat tccgatgctc tatttcgtgt taggggcact ctcctacatc ctgaaatggc
      541 cagcgctgaa tgaagacccc attaccaaaa ctattgcagc actcatcatt ctttgggcgc
      601 tggcattaac gcagtttggt ggcacgaaat acacggcgcg aattgctaaa gttggcttct
      661 tcgccggtat cctgttacct gcatttattt tgatcgcatt agcggctatt tatctgcact
      721 ccggtgcccc cgttgctatc gaaatggatt cgaagacctt cttccctgac ttctctaaag
      781 tgggcaccct ggtagtattt gttgccttca ttttgagtta tatgggcgta gaagcatccg
      841 caacccacgt caatgaaatg agcaacccag ggcgcgacta tccgttggct atgttactgc
      901 tgatggtggc ggcaatctgc ttaagctctg ttggtggttt gtctattgcg atggtcattc
      961 cgggtaatga aatcaacctc tccgcagggg taatgcaaac ctttaccgtt ctgatgtccc
     1021 atgtggcacc agaaattgag tggacggttc gcgtgatctc cgcactgctg ttgctgggtg
     1081 ttctggcgga aatcgcctcc tggattgttg gtccttctcg cgggatgtat gtcacagcgc
     1141 agaaaaacct gctgccagcg gcattcgcta aaatgaacaa aaatggcgta ccggtaacgc
     1201 tggtcatttc gcagctggtg attacgtcta tcgcgttgat catcctcacc aataccggtg
     1261 gcggtaacaa catgtccttc ctgatcgcac tggcgctgac ggtggtgatt tatctgtgtg
     1321 cttatttcat gctgtttatt ggctacattg tgttggttct taaacatcct gacttaaaac
     1381 gcacatttaa tatccctggt ggtaaagggg tgaaactggt cgtggcaatt gtcggtctgc
     1441 tgacttcaat tatggcgttt attgtttcct tcctgccgcc ggataacatc cagggtgatt
     1501 ctaccgatat gtatgttgaa ttactggttg ttagtttcct ggtggtactt gccctgccct
     1561 ttattctcta tgctgttcat gatcgtaaag gcaaagcaaa taccggcgtc actctggagc
     1621 caatcaacag tcagaacgca ccaaaaggtc acttcttcct gcacccgcgt gcacgttcac
     1681 cacactatat tgtgatgaat gacaagaaac actaaccatg tctgaatggt tataagacaa
     1741 gggagcgata attcatcgct ccctttttcg tgcttgctgt cgtattgact taacggggat
     1801 aagtacgaga atgagcgcac atctgtttac cggaaaccag cacatatgga tatctgctcc
     1861 cgaaacaaga aattaacgat tagaagacca gcgatactag ttgcactggc acttttactg
     1921 tgtagttgta aaagcacgcc tccagagtcc atggtgacac caccagcagg ttcaaagcca
     1981 ccagccacga cgcaacaatc gtcacaaccg atgcgtggca tctggctggc cacggtttct
     2041 cggctcgact ggccaccggt ttcctcggtt aacattagta accccaccag ccgggcccgt
     2101 gtacaacaac aggcgatgat cgacaaactg gatcatctgc aacgtctcgg cataaacacg
     2161 gtctttttcc aggtcaagcc ggacggtacc gccctgtggc catcgaaaat tttgccgtgg
     2221 tccgatctta tgaccggtaa gattggtgaa aatccgggtt acgatccgct gcaatttatg
     2281 ctcgacgaag cccacaagcg tgggatgaaa gtacacgcct ggtttaaccc ctatcgcgta
     2341 tcggttaata cgaagcccgg tactatcagg gaactgaata gcactctgtc tcaacaaccg
     2401 gcgagcgtct atgtgcaaca ccgcgactgg atcagaacgt ctggcgatcg ctttgtcctc
     2461 gacccgggca tccctgaggt tcaggactgg atcacatcaa tagtcgcaga agtggtttcc
     2521 cgctatcccg tagatggcgt gcagtttgac gactatttct atacggagtc accgggttca
     2581 cggctaaatg ataacgaaac gtaccgtaaa tacggaggcg catttgcgtc aaaagcagac
     2641 tggcggcgca acaatactca gcagttaatt gcaaaggtat cgcacaccat taaaagcatt
     2701 aagccgggag tcgaatttgg tgttagcccg gcaggcgtgt ggcgtaaccg atcacacgat
     2761 ccgctcggtt ccgatacccg aggcgcggca gcctatgacg aatcctacgc tgacacccgt
     2821 cgatgggtgg aacaaggatt gctggattac attgctcccc aaatttactg gccgttctca
     2881 cggagtgccg cgcgttatga cgtgttggca aaatggtggg cggatgtcgt taaaccgacc
     2941 aggacccgcc tgtatatcgg tatcgccttc tataaagtgg gtgaaccttc aaagatagag
     3001 ccagactgga tgattaacgg cggcgtaccg gaactgaaaa agcagctcga tcttaacgat
     3061 gctgtgcccg aaattagcgg caccatcttg ttccgtgagg actatctgaa taaaccgcag
     3121 actcaacaag cggtcagcta tctgcaaagt cgctggggca gttaaactcc cattcttact
     3181 ttgtaacaag ccggtgcttt acccaccggc ttgttaccct cttaaactat cccactaata
     3241 atcatgctta cttaagtcaa attaaccaca ct
//
LOCUS       DAPOAV010000215         3211 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.220, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000215 DAPOAV010000000
VERSION     DAPOAV010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3211
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.220"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(72..833)
                     /gene="kduD"
                     /locus_tag="RN951_004541"
     CDS             complement(72..833)
                     /gene="kduD"
                     /locus_tag="RN951_004541"
                     /EC_number="1.1.1.127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
                     KduD"
                     /protein_id="HDX2529405.1"
                     /translation="MILSAFSLEGKVAVVTGCDTGLGQGMALGLAQAGCDIVGINIVE
                     PTETIKQVTALGRRFLSLTADLRKIDGIPALLDRAVAEFGHIDILVNNAGLIRREDAL
                     EFSEKDWDDVMNLNIKSVFFMSQAAAKHFIAQGNGGKIINIASMLSFQGGIRVPSYTA
                     SKSGVMGVTRLMANEWAKHNINVNAIAPGYMATNNTQQLRADEQRSAEILDRIPAGRW
                     GLPSDLMGPIVFLASSASDYVNGYTIAVDGGWLAR"
     gene            complement(863..1699)
                     /gene="kduI"
                     /locus_tag="RN951_004542"
     CDS             complement(863..1699)
                     /gene="kduI"
                     /locus_tag="RN951_004542"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HDX2529406.1"
                     /translation="MDVRQSIHSAHAKTLDTQGLRNEFLVEEVFVADEYTMVYSHIDR
                     IIVGGIMPITKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCYEIGHRD
                     ALYVGKGAKEVVFASIDTATPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNR
                     RTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFH
                     MMGQPQETRHIVMHNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVKD
                     LR"
     gene            complement(1986..3167)
                     /locus_tag="RN951_004543"
     CDS             complement(1986..3167)
                     /locus_tag="RN951_004543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708633.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDX2529407.1"
                     /translation="MKDVVIVGALRTPIGCFRGALAGHSAVELGSLVVKALIERTGVP
                     AYAVDEVILGQVLTAGAGQNPARQSAIKGGLPNSVSAITINDVCGSGLKALHLATQAI
                     QCGEADIVIAGGQENMSRAPHVLTDSRTGAQLGNSQLVDSLVHDGLWDAFNDYHIGVT
                     AENLAREYGISRQLQDAYALSSQQKARAAIDAGRFKDEIVPVMIQSNGQTLVVDTDEQ
                     PRTDASAEGLARLNPSFDSLGSVTAGNASSINDGAAAVMMMSEAKARALNLPVLARIR
                     AFASVGVDPALMGIAPVYATRRCLERVGWQLADVDLIEANEAFAAQALSVGKMLEWDE
                     RRVNVNGGAIALGHPIGASGCRILVSLVHEMVKRNARKGLATLCIGGGQGVALTIERD
                     E"
BASE COUNT          849 a          880 c          723 g          759 t
ORIGIN      
        1 atggattatg atgatctaca ggtataaaaa accctgccat gcggcagggt cataaaagta
       61 agaagaatga attaacgcgc cagccaaccg ccatccacgg caatggtata accattcaca
      121 taatctgaag cgctggaggc aaggaacact atcggcccca tcaggtcact cggcagtccc
      181 caacgaccag ctggaatgcg gtcgagaatt tccgcgctac gttgttcatc tgcccgtagt
      241 tgttgagtat tgttggtcgc catgtaaccc ggagctatcg cattaacatt aatgttgtgt
      301 ttagcccatt cgttcgccat caatcgcgtc acacccatca cgccgctttt tgatgcggta
      361 taagaaggca cacggatccc gccctggaag gagagcattg acgcgatatt gataatcttg
      421 ccgccattgc cttgcgcgat aaagtgtttc gccgctgcct gagacatgaa gaatacgctc
      481 ttgatattca ggttcatgac atcgtcccag tccttttcgc tgaactcgag agcatcttcg
      541 cggcgaatca atccggcgtt attcaccagg atatcaatat gaccaaactc cgctaccgcg
      601 cgatccagca gtgctggaat accatcaatc tttcgcagat cggcggtcag gcttaaaaaa
      661 cgacgcccca gcgccgtgac ctgcttgatg gtttcagtag gttcaacgat gttaatgcca
      721 acaatgtcac agcccgcttg cgccagcccc aacgccatcc cctggcccag cccagtatca
      781 cagccagtga cgaccgcaac tttaccttcg agagaaaatg cacttaaaat cataacaata
      841 ccttattcgt ttatgcccac aactagcgca aatctttaac ggccacatgg tccatatcat
      901 caaagacctg gttttcaccg accatgcccc agataaaggt ataagctttg gttccgacgc
      961 cggaatgaat cgaccagctc ggggagatca ccgcctgctc gttatgcatc acaatatgac
     1021 gcgtttcttg cggctgcccc atcatgtgga aaacgcaggc gtcatcatcc atattgaaat
     1081 agaaataaac ttccatccgg cgctcgtgag tgtgacacgg catggtgttc cacaagttac
     1141 ctggagccag ctccgtcagc cccatactca attggcaggt ttccagcaca tccgggacaa
     1201 aatatttgtt aattgtgcga cggttactgg tgaggttatc gcctaacgtg actggagata
     1261 cttcgtccgg tgtgactttt ttggtgggat acgtcgtatg cgcgggtgcg caattgtaat
     1321 aaaactttgc cggagtggcg gtatcaatac tggcaaagac aacttctttt gcacctttac
     1381 ccacatacag ggcgtcgcgg tgaccgattt catagcattg gccatcgaca gtaatcgtac
     1441 cggcaccgcc aatattgata acacctaact cgcgacgttc aaggaaatag cttacgccga
     1501 gttgtttacc aacttccccg ccaacggaaa ccgttttagt tatcggcata atgccgccaa
     1561 caataattcg gtcaatgtgg ctgtaaacca tggtgtactc atcggcgaca aatacctctt
     1621 caaccaaaaa ttcattgcgc agcccttggg tatccagcgt ttttgcgtgc gcactgtgga
     1681 tgctctgtct tacgtccaca tcaacctccg ataatcagtg aagcgtgaaa atagaaaacg
     1741 atagtgaaac actgtttcgt tttctctata aagggatgat atgcccatgg gctagggttt
     1801 tcaattaaaa ataaaacaat gtttcatttt taagttaagg attaaaaaaa gtgcagtgtc
     1861 gatcacgaat atgtcatgag aatggaaaaa tgagggagcc cagaaaatgt atgtcgactt
     1921 gccagccatc attattcaac agattaatga cggcagatat ttatcggtaa ggaggaaatg
     1981 cagagctact cgtcacgttc aatggtcaat gccacgccct ggcccccgcc gatacaaagc
     2041 gttgccagcc ctttgcgggc attacgtttc accatttcat gaaccagaga aaccaggatt
     2101 cggcaaccgg aagcgcctat cgggtgaccg agtgcgatcg cgccaccatt gacattgacc
     2161 cgacgctcat cccactcaag catcttgcca accgaaagcg cctgtgcagc aaacgcttca
     2221 ttagcctcga taagatcgac atcagccaac tgccagccta cacgctccag gcaacggcgg
     2281 gtcgcataca ccggcgcaat tcccatcaat gccggatcta caccaacgct ggcaaatgcg
     2341 cggatgcggg ccagcacggg taaattcaac gctcgtgctt tggcttcgct catcatcatt
     2401 accgcagctg cgccatcgtt tatggatgat gcattccccg cggtcacaga accgagacta
     2461 tcaaatgaag gatttaaacg ggctaaacct tctgcactgg cgtcagtgcg tggctgttca
     2521 tcggtatcaa caaccaacgt ctgaccgtta ctttggatca ttaccgggac gatctcatct
     2581 ttaaatcgtc cggcgtcaat cgccgctcgc gctttttgtt gcgagctaag tgcgtaagca
     2641 tcctgcaact gacggctgat gccatattcg cgagccagat tttcggcggt gacaccaata
     2701 tgataatcat tgaaggcatc ccacaaccca tcatgcacca gactgtcaac caactggcta
     2761 ttgccaagct gtgcaccggt gcggctatca gtcagaacat gtggtgcgcg gctcatgttt
     2821 tcctggccac cggcgatgac aatatcagcc tcgccacact gtatcgcctg agtagccaga
     2881 tgcagtgctt taagcccaga accgcaaacg tcattaatag tgattgcaga aacgctatta
     2941 ggaagaccac ctttaatagc cgattgcctt gccggattct gccctgcccc tgcagtcaac
     3001 acctgaccaa gaattacttc atccaccgca tatgcaggaa cgccggtacg ttctattaac
     3061 gctttcacga ccagactacc aagttccacg gcggaatgac ccgctaacgc accgcgaaag
     3121 cagccgatag gtgtccgtaa cgccccgaca atcacaacgt ctttcatcac aacctcgcac
     3181 caattaacag tgcaatagta aatgattgtt a
//
LOCUS       DAPOAV010000216         3161 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.221, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000216 DAPOAV010000000
VERSION     DAPOAV010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3161
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.221"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            168..1238
                     /gene="rfaQ"
                     /locus_tag="RN951_004544"
     CDS             168..1238
                     /gene="rfaQ"
                     /locus_tag="RN951_004544"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptosyltransferase
                     RfaQ"
                     /protein_id="HDX2529408.1"
                     /translation="MEKPFRKILVIKMRYHGDMLLTTPVISTLKQNYPDAKIDMLLYQ
                     DTIPILSENPEINALYGISNKGTGTFDKIKNALSLIKTLRANNYDLVINLTDQWMVAL
                     LVRCLPARMKISQLYGHRQHGIWKKSFTHLAPIHGTHIVERNLSVLEPLGITDFYTET
                     TMSYAEDCWKKMRQELDALGVKDHYVVIQPTARQIFKCWDNDKFSMVIDALQHRGYQV
                     VLTCGPSADDLACVDEIARGCQTKPITGLAGKTRFPELGALIDHAVLFIGVDSAPGHI
                     AAAVKTPVISLFGATDHVFWRPWTENIIQFWAGNYQKMPTRHELDRNKKYLSVIPAED
                     VIAATEKLLPEDAPSADRNAQL"
     gene            1235..2359
                     /gene="rfaG"
                     /locus_tag="RN951_004545"
     CDS             1235..2359
                     /gene="rfaG"
                     /locus_tag="RN951_004545"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide glucosyltransferase I"
                     /protein_id="HDX2529409.1"
                     /translation="MIVAFCLYKYFPFGGLQRDFMRIASTVAARGHHVRVYTQSWEGD
                     CPEAFELIRVPVKSHTNHGRNAEYYAWVQNHLKAHPADRVVGFNKMPGLDVYFAADVC
                     YAEKVAQEKGFFYRLTSRYRHYAAFERATFEHGKSTKLMMLTDKQIADFQKHYQTEPE
                     RFQILPPGIYPDRKYNAQIPNSREIYRQKNGITEQQNLLLQVGSDFGRKGVDRSIEAL
                     ASLPESLRHNTLLFVVGQDKPRKFEVLAEKLGVRSKVHFFSGRNDVSELMAAADLLMH
                     PAYQEAAGIVLLEAIAAGLPVLTTAVCGYAHYITDANCGTVIAEPFSQEQLNDVLRKA
                     LTQSPLRMAWAENARYYADTQDLYSLPEKAADIITGGLDG"
     gene            2352..3149
                     /gene="rfaP"
                     /locus_tag="RN951_004546"
     CDS             2352..3149
                     /gene="rfaP"
                     /locus_tag="RN951_004546"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(I) kinase RfaP"
                     /protein_id="HDX2529410.1"
                     /translation="MVELEEPLATLWRGKDAFAEVKKLNGEVFRELETRRTLRFELAG
                     KSYFLKWHKGTTLKEIIKNLLSLRMPVLGADREWHAIHRLHDVGVDTMHGIGFGEKGL
                     NPLTRTSFIITEDLTPTISLEDYCADWAVNPPDVHIKRMLIARVATMVRKMHAAGINH
                     RDCYICHFLLHLPFTGREDELKISVIDLHRAQIRAKVPRRWRDKDLIGLYFSSMNIGL
                     TQRDIWRFMKVYFGMPLRDIYRLEIDLLKKARIKAGKIEARTIRKNL"
BASE COUNT          891 a          642 c          746 g          882 t
ORIGIN      
        1 catattttgt gtataaaaat cattcgggtc ggattgctgc gaaagaaatg atacactagc
       61 gcgtcaaagt aagtgcgtta tcagtattcg ggtagctgtt gagcctgggg cggtagcgtg
      121 cttttttctg cttaacttaa ccagacaatc acacaaaaga gtcgctagtg gaaaagccat
      181 ttcgaaaaat cctggtcata aagatgcgat atcacggaga tatgttatta actactcctg
      241 taatcagtac actcaagcag aattatcccg acgcaaaaat cgatatgctg ctttaccagg
      301 atacaattcc gattttatct gaaaacccag aaattaatgc actctatggt ataagcaata
      361 aaggtacggg aacattcgat aaaattaaaa atgcactttc actgataaaa actctgcgtg
      421 cgaataatta cgacctggtc attaatctta cggatcagtg gatggtggcc ctgctggtac
      481 gttgtttacc tgctcgtatg aaaatatcgc agctttatgg tcatcggcag catggcattt
      541 ggaaaaaaag ctttacacac ttagcgccta tacacggtac acatattgtt gagcgtaatt
      601 tgtcggtcct tgagccatta ggtattaccg atttttatac tgaaacaacc atgagttacg
      661 ccgaggattg ctggaagaaa atgcgccagg aattagatgc actgggcgtg aaagatcatt
      721 atgtcgtcat ccagccgaca gccagacaga tatttaagtg ctgggacaac gataaatttt
      781 ctatggttat cgatgcgttg caacatcgtg gttatcaggt tgtgctgact tgtggccctt
      841 cggcagatga tctcgcttgc gtagatgaaa ttgcacgagg ctgccaaaca aaacctatta
      901 ccggccttgc cggtaaaaca cgttttcctg aactgggcgc attaattgat catgcagtgc
      961 tctttattgg tgtggattct gcgccggggc atattgcagc ggctgtgaag acgccagtta
     1021 ttagcctgtt tggggccact gatcatgtat tctggcgtcc atggaccgag aatattattc
     1081 agttctgggc ggggaattat caaaaaatgc ctacccggca cgaacttgac cgcaacaaaa
     1141 aatatctttc tgttattcca gcggaagatg tcattgccgc tacggaaaag ctgttgccag
     1201 aagatgcacc ttcagctgac aggaatgcgc aattatgatc gtggcatttt gcttatataa
     1261 atattttcca tttggtgggc tacagcgtga ctttatgcgt attgcctcaa cagttgccgc
     1321 acggggccac catgttcggg tatatacaca gtcgtgggaa ggcgattgcc cggaagcatt
     1381 tgagcttatt cgcgtaccgg ttaaatccca tactaaccat ggacgtaatg cagaatatta
     1441 tgcctgggtt caaaaccatc tgaaggcaca tcccgctgat cgcgttgttg gctttaataa
     1501 gatgcctggg ctggatgttt attttgccgc cgatgtctgt tatgccgaga aagtggcgca
     1561 agaaaaggga tttttctatc gtttaacatc gcgctatcgc cattatgctg cattcgagcg
     1621 agcgactttc gaacatggta aatcgacgaa acttatgatg ttgaccgata agcaaatcgc
     1681 cgattttcag aagcattacc aaactgaacc agaacgtttt caaattcttc cccctggtat
     1741 ctatcctgac agaaaataca acgcgcaaat cccaaacagt cgtgaaattt atcgccagaa
     1801 aaatggcatc actgaacaac aaaacttatt gctgcaggtt ggttcagatt ttggtcgtaa
     1861 aggtgtggat cgctcaattg aagctttggc atcgttacca gaatcgttac gccataatac
     1921 gttgttgttt gttgttggcc aggataaacc gcgtaaattt gaagtgctgg cagaaaaact
     1981 cggtgtgcgt agtaaagtgc atttcttttc cgggcggaat gatgtgtctg aattaatggc
     2041 agccgctgat ttattaatgc atcccgctta tcaggaggct gcaggtattg ttctccttga
     2101 ggcaattgcc gcgggattac ctgtgttgac gactgcggta tgcggatacg cacactatat
     2161 cacagatgct aattgtggaa cggtcatcgc tgaacctttc tcccaggaac aattaaatga
     2221 cgttttacgt aaagcgttaa ctcaatctcc attgcgcatg gcctgggcgg agaatgctcg
     2281 gtattacgcc gatactcagg atttatacag cctgccggag aaagcggcag atatcattac
     2341 aggtggttta gatggttgaa ttagaagagc cacttgccac actctggcgt ggtaaagatg
     2401 cctttgcaga agttaaaaaa ctgaatggcg aggtcttccg tgaactggag acgcgtcgca
     2461 cattacgctt tgaactggcc ggcaaaagtt atttcctcaa atggcacaaa gggacgaccc
     2521 taaaggagat tataaaaaat ctgctctcat tgcggatgcc cgttttaggt gcagacagag
     2581 agtggcacgc tattcatcga ctgcatgatg tcggtgttga tacgatgcac ggaataggat
     2641 ttggtgaaaa agggttaaat ccattaactc gcacatcatt tattattacc gaagatctca
     2701 ctcccacaat tagccttgaa gattattgtg cagattgggc ggtcaacccg cctgatgtac
     2761 atattaagcg tatgctgatc gcgcgtgtgg caaccatggt gcgcaaaatg catgcagcag
     2821 ggattaatca ccgtgattgt tatatctgcc actttttact ccatttgcca tttactggcc
     2881 gggaagatga attaaaaatt tcggttatcg atctgcaccg ggcacagata cgtgcaaaag
     2941 taccacgtcg ttggcgggat aaagatttga ttggtttata tttctcatca atgaatattg
     3001 gtctgacgca gagagatatc tggcgattta tgaaggttta ttttgggatg cctttacgcg
     3061 atatttatag acttgagatt gatttactta aaaaggcaag gattaaagca ggaaaaatag
     3121 aagcaagaac aataagaaaa aacttgtaaa tagtatttta t
//
LOCUS       DAPOAV010000217         3133 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.222, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000217 DAPOAV010000000
VERSION     DAPOAV010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3133
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.222"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(595..918)
                     /locus_tag="RN951_004547"
     CDS             complement(595..918)
                     /locus_tag="RN951_004547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nikA protein"
                     /protein_id="HDX2529411.1"
                     /translation="MTKRSGSNTRRRAISRPVRLTAEEDQEIRKRAAECGKTVSGFLR
                     AAALGKKVNSLTDDRVLKEVMRLGALQKKLFIDGKRVGDREYAEVLIAITEYHRALLS
                     RLMAD"
     gene            1203..1397
                     /locus_tag="RN951_004548"
     CDS             1203..1397
                     /locus_tag="RN951_004548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="HDX2529412.1"
                     /translation="MNKQQQTALNMAKFIKSQSLTLLEKLDSLDADAQAAMCEKLHEL
                     AEELQNSIQTRFESESGTGE"
     gene            2349..2492
                     /locus_tag="RN951_004549"
     CDS             2349..2492
                     /locus_tag="RN951_004549"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529413.1"
                     /translation="MNTKVLFVKKALKSITCAILSLLPALSRAVTELRSLSAARLKAG
                     KSF"
     gene            complement(2517..>3133)
                     /locus_tag="RN951_004550"
     CDS             complement(2517..>3133)
                     /locus_tag="RN951_004550"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529414.1"
                     /translation="LVQMIEVALRNAINNTIKANHGPAWYDSIPQTKKSQDLVLNAKQ
                     KALDECGVRYTDDDVICRLTFGFWVYMLDAPYRDTQRPCYIWTPENKAKTFPHAKNPL
                     GGGDMKVKALFDEFHKVLLFRNRLFHHEPIWKKHHCKSHSQAINNMLKEFNFLMNALS
                     IVSNEKKELIEFIGHDRRFYERCTIEYVMGIIGRIKCRELKVAG"
BASE COUNT          908 a          766 c          650 g          809 t
ORIGIN      
        1 aaaaaaaatc gccagacaga tcttggtagg caacgtatgc cccaaccttt tcttgatcag
       61 tagcgcaccc aagaaatgtt tcatagaaag ataatcttgg tacagaaatt gagctaatta
      121 aacttgttgt atccatgaaa actcacttat ctctttacta tgaatatttt tcagactacc
      181 attacaacat tcgaggagca ggcgaactac cgtttttctg tgtacctcta gagcgtaaaa
      241 tataacaaaa aagcccacta cagagtgggc ttttttgtta tatttatcta tatgaaacaa
      301 ccagttatag ttattgtttc ataataagaa ttgaatactc ttcacaatcc acaacatcag
      361 aaaatacttt gctgccaatt taccataact ccccttacgc gcaccgctaa aacgcgctga
      421 acgcgattct gccgcaaaca ccgcaaaaag agatgtttta cccagtgaaa accggaaaaa
      481 tgcgtcagga ccgttttcag ctcactgcat agctatgcat gaaagtgaat ggcgatcggt
      541 ttggggcctt acggcgttca taccgtctgt tttcgacagt ttctctccgg gaagctaatc
      601 tgccataagc ctggataaca gggcccggtg atactccgta atagcgatca gcacctccgc
      661 atactctctg tccccgacac gcttgccgtc gataaagagt tttttctgta acgcccccag
      721 tctcataact tctttcagta cccgatcatc agtcagtgag ttaactttct taccgagagc
      781 tgccgcccgt aaaaaaccgg aaacggtctt gccgcattca gcagcccttt ttctgatttc
      841 ctggtcttct tctgccgtca gacgaacagg gcgactgata gcccgcctgc gcgtattact
      901 tccacttcgt tttgtcataa aacatggctc cgtatctgac atggggtgtc ggggcgaagc
      961 cctgaccagg gtaattgtaa tagcgcgcat gtatgcgcgg tataacaatt acacatcctg
     1021 tcctgtcagc aagttcgaat taccgacaaa ggcacggcag ttttttggca gtgacagtat
     1081 tgtcaggcag aaatgcccgt caaagagtca gacgacagaa taccggcggc aaaactgtcg
     1141 aaaagtggta cgcgatataa tcacacgacg cagatgacag acagaacgga gaaaacagaa
     1201 agatgaacaa gcagcagcaa accgcactta acatggcaaa attcataaaa agccagagcc
     1261 tgacgctgct cgaaaaactg gactcactcg atgctgatgc acaggccgcc atgtgtgaga
     1321 aactgcacga actcgcagaa gaactccaga acagcataca gacacgcttt gaatcggaaa
     1381 gtggcaccgg ggaataacag tgttcctaca ccagacagga tgcagaacga tataccggtg
     1441 cgtaaggaga aaataccaca taaggcgctc ttccgcttcc tcgctcacta actcgctacg
     1501 ctcggtcgtt cggctgcggc gagcggtatc agctcactca aagacggtaa tgaggttatc
     1561 cacagaatca ggggataacg ccaaaagaaa catgtgagca aaaaacaaga acccgaaaaa
     1621 ggccgcgccg gtggcgtttt tccataggct ccgcccccct gacgagcatc acaaaaatcg
     1681 acgctcaagt cagaggtggc gaaacccgac aggactataa agataccagg cgtttccccc
     1741 tgatggctcc ctcgtgcgct ctcctgttcc tgcctttcgg tttaccggtg tcattccgct
     1801 gttatggccg cgttatctca ttccacgcct gacactcagt tccgggtagg cagttcgctc
     1861 caagctggac tgtatgcacg aaccccccgt tcagtccgac tactgcgcct tatccggtaa
     1921 ctatcgtctt gagtccaacc cggaaaggca cgacttatcg ccattggcag cagccactgg
     1981 taactgattt agaggagtta gtcttgaagt tacgtgccag ttaaggctaa actggaagaa
     2041 caagttttgg tgactgcgct cctcttaagc cagttaccga ggttcagaaa cttgccggtt
     2101 gctgaacctt cgaaaaacca ccttgccggg tggttttttc gtttttaaga ttacgatggg
     2161 cgcgatatga actcaaggaa atccgcaatt aaattataaa agtttgtgga ttaatggaaa
     2221 aactgatgtg aatcagctat ttatccttaa gatttgatgt cagatatggt ataattaacc
     2281 attcaaatag atggaataaa aagtcaacgc tgccattaga acggcataag aaatagagga
     2341 ttatgaaaat gaatactaaa gttctttttg tgaaaaaagc cttgaaatca attacttgcg
     2401 caattctttc gctcttaccg gctttaagtc gcgcagtaac agagttacgt agcctttcgg
     2461 ctgcgcgact taaagccggt aagagctttt gattgtatca catttttcct taaaagtcaa
     2521 ccggctacct taagctccct gcacttaatc ctccctataa tccccataac atactctatc
     2581 gtgcagcgtt cataaaagcg cctatcgtgc ccaataaact caataagttc ctttttctcg
     2641 ttagagacga tactcaaggc attcattaaa aaattgaact ctttcaacat attatttatg
     2701 gcttgactat gcgacttgca gtggtgtttt ttccaaatag gctcatggtg aaaaagtcga
     2761 ttcctaaaca aaagaacttt atgaaactcg tcaaacaacg ctttaacctt catatccccc
     2821 ccacccaaag gattcttcgc atgaggaaat gtttttgcct tgttctctgg agtccagatg
     2881 tagcacggcc tttgcgtatc cctatatggg gcatctaaca tataaaccca aaagccaaag
     2941 gttagacggc aaataacatc atcatccgta taccttacgc cacactcatc tagcgctttt
     3001 tgtttcgcat ttaaaacaag atcctgagat ttctttgttt gaggtataga gtcgtaccaa
     3061 gcaggcccat gattagcttt gattgtattg tttatcgcat tacgcagagc aacctcaatc
     3121 atctggacaa gac
//
LOCUS       DAPOAV010000218         3111 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.223, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000218 DAPOAV010000000
VERSION     DAPOAV010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3111
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.223"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(91..1950)
                     /gene="gss"
                     /locus_tag="RN951_004551"
     CDS             complement(91..1950)
                     /gene="gss"
                     /locus_tag="RN951_004551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutathionylspermidine
                     amidase/synthase"
                     /protein_id="HDX2529415.1"
                     /translation="MSKGTTSQDAPFGTLLGYAPGGVAIYSSDYSSLDPQEYEDDAVF
                     RSYIDDEYMGHKWQCVEFARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQ
                     AFPNGSPRAPVAGALLIWDKGGEFKDTGHVAIITQLHGNKVRIAEQNVIHSPLPQGQQ
                     WTRELEMVVENGCYTLKDTFDDTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLEN
                     KGQFDGKWLDEKDPLQNAYVQANGQVINQDPYHYYTITESAEQELIKATNELHLMYLH
                     ATDKVLKDDNLLALFDIPKILWPRLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNAD
                     SASCHTEAGLILERWAEQGYKGNGFNPAEGLINELAGAWKHSRARPFVHIMQDKDIEE
                     NYHAQFMEQALHQAGFETRILRGLDELGWDAAGQLIDGEGRLVNCVWKTWAWETAFDQ
                     IREVSDREFAAVPIRTGHPQNEVRLIDVLLRPEVLVFEPLWTVIPGNKAILPILWSLF
                     PHHRYLLDTDFTVNDELVKTGYAVKPIAGRCGSNIDLVSHHEEVLDKTSGKFAEQKNI
                     YQQLWCLPKVDGKYIQVCTFTVGGNYGGTCLRGDESLVIKKESDIEPLIVVKK"
     gene            2155..3021
                     /gene="yghU"
                     /locus_tag="RN951_004552"
     CDS             2155..3021
                     /gene="yghU"
                     /locus_tag="RN951_004552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HDX2529416.1"
                     /translation="MTDNTYQPAKVWTWDKSAGGAFANINRPVSGPTHEKTLPVGKHP
                     LQLYSLGTPNGQKVTIMLEELLALGVTGAEYDAWLIRIGDGDQFSSGFVEVNPNSKIP
                     ALRDHTHNPPIRVFESGSILLYLAEKFGYFLPQDLAKRTETMNWLFWLQGAAPFLGGG
                     FGHFYHYAPVKIEYAINRFTMEAKRLLDVLDKQLAQHKFVAGDEYTIADMAIWPWFGN
                     VVLGGVYDAAEFLDAGSYKHVQRWAKEVGERPAVKRGRIVNRTNGPLNEQLHERHDAS
                     DFETNTEDKRQG"
BASE COUNT          734 a          831 c          786 g          760 t
ORIGIN      
        1 taaatattgg aatatataaa tattgaatat tttgattaat ccccgtactg attattcttc
       61 ataatcagta cggggttgct acaacatgta ttactttttc accacaatta acggttcaat
      121 atcactctct tttttgatga ccagtgattc atcaccgcgc aaacacgtcc caccgtagtt
      181 gccgccaacg gtgaaggtac atacctgaat gtatttaccg tccactttcg gcaaacacca
      241 cagttgctga tagatgtttt tctgctcggc aaatttaccg ctggttttgt ccagcacctc
      301 ttcatgatgg ctgacgaggt cgatattgct gccacagcga ccggcgatcg gtttcactgc
      361 gtaacctgtt ttcaccagtt catcattaac agtgaaatcg gtatccagca ggtaacgatg
      421 gtgcgggaac agcgaccaga ggatcggcag aatcgctttg ttgccgggga tcaccgtcca
      481 cagcggctca aagaccagca cttccgggcg cagcaatacg tcgataagac gcacttcgtt
      541 ttgcggatga ccggtacgga ttggcaccgc agcaaactca cggtcgctaa cttcacgaat
      601 ctgatcaaac gcggtttccc acgcccaggt tttccacacg cagttaacca gccgtccttc
      661 cccatcaatc agttgcccgg cagcatccca gcccagttca tccagcccgc gcaagatacg
      721 cgtttcaaag cccgcctggt gcagcgcctg ctccataaac tgcgcgtgat agttttcctc
      781 gatatctttg tcctgcatga tatggacaaa cggacgtgca cgactgtgtt tccaggcacc
      841 agccagttcg ttaatcagcc cttccgccgg attgaagccg ttgcctttat agccctgctc
      901 cgcccaacgt tcgaggatca agcccgcttc ggtatgacat gaggcagagt cggcgttgta
      961 ctcgtaaacc ttcagaccac gctcatccat gcagaaatcc atacgaccgg tgatcatatg
     1021 gtgacggcga cgctgccagg agagacgcaa acgtggccag aggattttcg ggatgtcgaa
     1081 cagcgccagc aggttgtcat ctttcagcac cttgtcggtt gcgtgaagat acatcaggtg
     1141 cagctcgttg gtggctttaa ttagctcctg ctcggcactc tcggtaatgg tgtagtaatg
     1201 atacggatcc tgattgatca cctgaccgtt ggcctgcaca taggcgtttt gcagcggatc
     1261 tttttcatcc agccatttac cgtcaaactg gcctttgttt tccaggcgcg ctccgctgat
     1321 tttcagcagc tcgcctgcaa tttccggctg cggtaagctg tattcagtat cttccgtctg
     1381 gatcatccag cccagaatgg tggtgtcatc aaaagtgtct ttcagggtat agcagccgtt
     1441 ttcgaccacc atctccagct cacgcgtcca ctgttgccct tgcggcaacg gggaatgaat
     1501 cacgttctgt tccgcaatac ggactttgtt gccatgcaat tgggtaatga tggcgacatg
     1561 gccagtgtct ttaaattcac cgcctttatc ccagataaga agcgcacccg cgaccggcgc
     1621 acgcggcgag ccgttaggaa atgcctgcaa tggcaggatg ttgtcattaa ccacttctcg
     1681 caggaagcgc agcgagaaaa tctcccacgc catacccacg tcagtaaaga ccacaccgta
     1741 attcagaaag agaaaacggc gagcaaattc aacgcattgc cacttgtggc ccatatattc
     1801 gtcgtcgata tagctacgga atacggcgtc atcttcgtat tcctgcggat cgagagaact
     1861 gtaatctgaa gagtagattg ctaccccacc tggggcgtag cccaataatg tcccgaacgg
     1921 ggcatcctgg ctggtcgttc ctttgctcat cactttacct ttaacaatac aacctaagca
     1981 gttggcgtaa ttgttgtgct ctgattacct gctcagcgac attaaccgga cagaggtcag
     2041 actaatcata cacctcatcg cagcggctgg cgcaaagggt taaaaaattc acattctgta
     2101 cagcaagtga cctgctacac tgcttcaaca ctaccactca gaaggcaact cactatgaca
     2161 gacaatactt atcagcccgc gaaagtctgg acgtgggata aatccgctgg cggcgcgttc
     2221 gccaatatca atcgcccggt ttctggtccg acgcatgaaa aaacgctgcc cgttggcaaa
     2281 cacccattgc aactttattc gctgggaacg ccgaacggtc agaaagtaac gattatgctt
     2341 gaggagctgc tggcgctggg cgttactggt gcagagtacg acgcctggct gattcgtatt
     2401 ggcgatggcg atcaattctc cagcggcttt gtcgaagtga acccaaactc gaagatcccg
     2461 gcgctgcgcg atcatacgca taatccgccg atccgcgtgt ttgaatctgg ttcgatcctg
     2521 ctttatctgg cggagaaatt tggctacttc ctgccgcagg atttggcaaa gcgtactgaa
     2581 acgatgaact ggctgttctg gttacagggc gcggcaccgt tcctcggcgg tggttttggt
     2641 cacttttacc attacgcacc ggtaaagatt gagtacgcca tcaaccgctt taccatggaa
     2701 gccaaacgtc tgctcgacgt gctggataag caactggcgc agcataagtt tgttgcgggc
     2761 gatgagtaca ccattgcgga tatggcgatt tggccgtggt ttggcaacgt ggtgttaggc
     2821 ggcgtgtatg atgccgcaga gtttcttgat gcgggcagtt ataagcatgt acaacgctgg
     2881 gcgaaagaag taggcgaacg tccggcggtg aaacgtgggc gtattgttaa ccgcaccaac
     2941 ggaccgctga atgagcagtt gcatgagcgc catgacgcca gtgatttcga gacgaatacg
     3001 gaagataagc gtcaggggta agggttggtg ttcgtcgcag caagccatcc aggccggata
     3061 aggcgttcac gccgcatccg gcaatcgtgc acaatgcctg atgcgacgct g
//
LOCUS       DAPOAV010000219         3100 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.224, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000219 DAPOAV010000000
VERSION     DAPOAV010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3100
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.224"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            591..1946
                     /gene="ltrA"
                     /locus_tag="RN951_004553"
     CDS             591..1946
                     /gene="ltrA"
                     /locus_tag="RN951_004553"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: protein motif:HMM:TIGR04416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDX2529417.1"
                     /translation="MNLNSHRSPCCDSDEQRSTVNNTSNEYNQIDHDLMAKVLSNHNI
                     SAAWQHVKRNKGAAGIDNMSIEEFNDFAKLHWLGIKQQLLNGSYQPLPVKRVMIPKPD
                     GGERMLGIPAVIDRVIQQAIAQVISPYFEPQFSPHSYGYRPHKRASQAVNHVQSCVKQ
                     GYKTAVDIDLSKFFDEVDHDMLMNRVGRKIKDKALMRLLGKYLRAGIAERETGLWFES
                     TKGVPQGGPLSPLLSNILLDELDKKLTYKHLKFARYADDIIILVKTKSEGLIIQREIT
                     AFITKRLKLKVNESKSRVGPVSGSKFLGFTFRYGQVQIHEQALKKFKANVRELTNRNW
                     GISMTLQIHKLTQYLRGWGHYYLIANAYQLTVDLDHWIRRRIRMCYWRQWRKPRTKVR
                     SLMKLGVSERLAIACGITSKGPCRSSKTKGINIALGNNYLASQGLVSLRDIWINIHYG
                     R"
     gene            complement(1993..2253)
                     /locus_tag="RN951_004554"
     CDS             complement(1993..2253)
                     /locus_tag="RN951_004554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1010 domain-containing protein"
                     /protein_id="HDX2529418.1"
                     /translation="MFIQTAFSFSGVIQCLFCLFSGLRLHGLRRFSVFLASSPCVASA
                     SSYRFCSAVPPRWRSVFSRLAPVAKFKLSVLASGSNRVAGGL"
     gene            complement(2365..2862)
                     /gene="dfrA12"
                     /locus_tag="RN951_004555"
     CDS             complement(2365..2862)
                     /gene="dfrA12"
                     /locus_tag="RN951_004555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004187529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrA12"
                     /protein_id="HDX2529419.1"
                     /translation="MNSESVRIYLVAAMGANRVIGNGPNIPWKIPGEQKIFRRLTEGK
                     VVVMGRKTFESIGKPLPNRHTLVISRQANYRATGCVVVSTLSHAIALASELGNELYVA
                     GGAEIYTLALPHAHGVFLSEVHQTFEGDAFFPMLNETEFELVSTETIQAVIPYTHSVY
                     ARRNG"
BASE COUNT          913 a          690 c          783 g          714 t
ORIGIN      
        1 ggagttaagc cgccgcgcgt agcgcggtcg gcttgaacga attgtgtacg cccgacatgg
       61 gcattgactt atgaggtgaa agtcctctgt aggaagatca ccgtttaaat aacatactgt
      121 tattaaacga taactactag cgaatggcaa gggctaaatc gcgagagata gtctgaagga
      181 agccgctagc aaatctgtga gctgatgaac aaaaacatca tatgaggcgt aggctggaga
      241 cgagctagca caagatagcg aagtcatgtg atctaacggc caccgtaaat gatgcagttg
      301 tgcagagaaa gtcgatgcat cttattcggg gagatctgat aaacacgcat ccgcgctaac
      361 gcttggagat taccagttag ggactggttg ttcaaccctt ggcgctttgg ttgctgcgac
      421 ctacagcgag cgaaatagca gtaaacaagc gttagtttta gacgcgcttt atcgagtaat
      481 cgctagagtg atttatcaga agtcagcaga cggcatagta gccaaacgcc catcgtaatg
      541 gaggggacac ggtgaaggcc tgaacatctt aaccagagga gacactacaa atgaacttga
      601 attcacatag atcaccgtgt tgtgatagtg atgaacagcg ttcgactgtg aataatacct
      661 cgaatgaata taaccaaata gatcatgacc ttatggcaaa ggtactaagc aaccacaata
      721 ttagcgcagc atggcaacat gttaagcgca ataaaggggc tgcgggtatt gataatatga
      781 gtattgagga atttaatgac ttcgctaagt tacattggct gggtattaaa caacaattac
      841 ttaacggcag ttatcaaccc ttgccagtca aacgcgtgat gatacctaaa cctgatggcg
      901 gtgagcgaat gcttgggatc cctgctgtta tcgacagagt gatccaacaa gccattgctc
      961 aagtgatcag cccttacttt gagcctcaat tttcaccaca tagttatggt tatcgccctc
     1021 ataaaagagc cagtcaagca gtgaaccatg ttcagtcttg tgttaaacaa ggttataaaa
     1081 cagcggttga tatcgacttg tctaagttct ttgatgaagt agaccatgac atgctgatga
     1141 atcgtgttgg ccgtaaaatc aaagacaaag cactcatgcg cctactcggt aaatacttac
     1201 gagcggggat cgcagagcgc gaaacaggtc tgtggtttga gtcaaccaaa ggagtccctc
     1261 aaggtgggcc attatcccct ttgctttcca acatcttact cgatgaatta gataagaagc
     1321 taacctacaa acaccttaag tttgcacgtt acgctgatga cataatcatt ttagtaaaaa
     1381 cgaaaagcga aggattaata atccagcggg aaattactgc gttcatcact aagcgattaa
     1441 agctcaaagt gaacgaatcg aaaagtcgag tgggtccagt atcaggctca aaatttctcg
     1501 ggttcacatt ccgttacggt caagtgcaga tccacgaaca ggcgctaaag aaattcaaag
     1561 caaatgtcag ggaactcact aaccgcaact gggggatctc aatgacccta caaattcata
     1621 aactcacgca gtatttgcgc ggctggggac actactacct gatagccaac gcttatcagc
     1681 taacggtgga tttagatcat tggatccgac gtaggataag aatgtgctac tggcggcaat
     1741 ggcgtaaacc tcgcaccaaa gtacgcagtt taatgaaatt gggtgttagc gaacgactcg
     1801 ccatagcctg tggtatcacc agtaaaggcc cttgtagaag ctcaaaaaca aaaggtatta
     1861 acattgcgct aggcaataac tacttagctt cacaaggttt agtgtcattg agggatattt
     1921 ggatcaatat tcattacggg agatgaaccg cccattgcgg acccgcatga tgggtggtgt
     1981 gggggctgga ggttagagac ctccggctac ccgattagaa ccagaagcca aaacggataa
     2041 cttgaatttg gcgacgggcg ctaaccgtga aaaaacgctg cgccaccgag gcggcacagc
     2101 actgcaaaaa cgatagctgc ttgcgcttgc tacgcaaggg ctagaggcca aaaagactga
     2161 aaacctgcgc agcccatgca ggcgaagccc ggaaaaaagg caaaacaggc actgaataac
     2221 gcctgaaaag ctaaatgccg tttgaataaa catgagctaa ataaagctgg gtttaagtgg
     2281 tgctaacgtt ggacgtaacg agagccggag cgcagcggag ggaaccaaaa tgcgcagcat
     2341 tttggcgtcc cgttgacgga atggttagcc gtttcgacgc gcataaacgg agtgggtgta
     2401 cggaattaca gcttgaatgg tttcggttga gacaagctcg aattctgttt cgttgagcat
     2461 tgggaagaag gcgtcaccct cgaaggtttg atgtacctca gatagaaaca cgccgtgggc
     2521 gtgaggtagt gccagagtgt atatctcagc tccgcccgcg acgtagagtt cattgccgag
     2581 ttcggatgcc aaagcgatag cgtgcgacag cgttgaaaca actacgcagc cagtggcgcg
     2641 gtagttagct tggcgtgaga ttaccaatgt gtgacggttc ggtagaggct tgccgataga
     2701 ctcaaaggtc tttcgcccca tgacaacgac ttttccctca gtgagtctgc gaaaaatctt
     2761 ctgctcaccc ggaattttcc aggggatatt aggaccattg ccaataaccc gattggctcc
     2821 catcgcagca acgagataaa tgcgtactga ttccgagttc atatggctaa ctttgtttta
     2881 gggcgactgc cctgctgcgt aacatcgttg ctgctccata acatcaaaca tcgacccacg
     2941 gcgtaacgcg cttgctgctt ggatgcccga ggcatagact gtacaaaaaa acagtcataa
     3001 caagccatga aaaccgccac tgcgccgtta ccaccgctgc gttcggtcaa ggttctggac
     3061 cagttgcgtg agcgcatacg ctacttgcat tacagcttac
//
LOCUS       DAPOAV010000220         3075 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.225, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000220 DAPOAV010000000
VERSION     DAPOAV010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3075
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.225"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            515..1681
                     /gene="nhaA"
                     /locus_tag="RN951_004556"
     CDS             515..1681
                     /gene="nhaA"
                     /locus_tag="RN951_004556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaA"
                     /protein_id="HDX2529420.1"
                     /translation="MKHLHRFFSSDASGGIILIIAAILAMIMANSGATSGWYHDFLET
                     PVQLRVGSLEINKNMLLWINDALMAVFFLLVGLEVKRELMQGSLASLRQAAFPVIAAI
                     GGMIVPALLYLAFNYADPITREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALA
                     IIDDLGAIIIIALFYTNDLSMASLGVAAVAIAVLAVLNLCGVRRTGVYILVGVVLWTA
                     VLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSL
                     QGVTLDGLTSILPLGIIAGLLIGKPLGISLFCWLALRLKLAHLPEGTTYQQIMAVGIL
                     CGIGFTMSIFIASLAFGSVDPELINWAKLGILVGSISSAVIGYSWLRVRLRPSV"
     gene            1747..2646
                     /gene="nhaR"
                     /locus_tag="RN951_004557"
     CDS             1747..2646
                     /gene="nhaR"
                     /locus_tag="RN951_004557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705976.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator NhaR"
                     /protein_id="HDX2529421.1"
                     /translation="MSHINYNHLYYFWHVYKEGSVVGAAEALYLTPQTITGQIRALEE
                     RLQGKLFKRKGRGLEPSELGELVYRYADKMFTLSQEMLDIVNYRKESNLLFDVGVADA
                     LSKRLVSSVLNAAVVEGEPIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQEGL
                     FSVRIGECGVSFWCTNPPPEKPFPACLEERRLLIPGRRSMLGRKLLNWFNSQGLNVEI
                     LGEFDDAALMKAFGAMHNAIFVAPTLYAYDFYADKTVVEIGRVENVMEEYHAIFAERM
                     IQHPAVQRICNTDYSALFSPAAR"
     gene            complement(2684..>3075)
                     /locus_tag="RN951_004558"
     CDS             complement(2684..>3075)
                     /locus_tag="RN951_004558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000871680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="fimbrial family protein"
                     /protein_id="HDX2529422.1"
                     /translation="GRFVLSRINNENYQFHHIRFDCIQGEQGELVFEPSDVEYYFEPV
                     MIQESGTSILKNDLENSEDGAGQIGFQLSNDGTHEIQYGKSNYYSFQHPHEGSNQIPL
                     FIRPRTYGNNVSSGKIMSRVKIVVMYN"
BASE COUNT          734 a          686 c          749 g          906 t
ORIGIN      
        1 gttgatagta aaatatcact cggggctttt ctctatctgc cgttcagcta atgcctgaga
       61 cagacagcct caagcacccg ccgctattat atcgctctct ttaacccatt ctgttttatc
      121 gattctaatc ctgaagacgc ctcgcatttt tgtggcgtaa ttttttaatg atttaattat
      181 ttaactttaa tttatctctt catcgcaatt attgacgaca agctggatta tttttgaaat
      241 attggcctaa caagcatcgc cgactgacaa caaattaatt attacttttc ctaattaatc
      301 cctcaggaat cctcacctta agctatgatt atctaggctt agggtcactc gtgagcgctt
      361 acagccgtca aaaacgcatc tcaccgctga tggcgaaaat tcttcaatag ctcgtaaaaa
      421 acgaattatt cctacactat aatctggttt taacgatgat tcgtgcgggg taaaatagta
      481 aaaacgatct attcacctga aagagaaata aaaagtgaaa catctgcatc gattctttag
      541 cagtgatgcc tcgggaggca ttattcttat cattgccgct atcctggcga tgattatggc
      601 caacagcggc gcaaccagtg gatggtatca cgactttctg gagacgccgg ttcagctccg
      661 ggttggttca ctcgaaatca acaaaaacat gctgttatgg ataaatgacg cgctgatggc
      721 ggtatttttc ctgttagtcg gtctggaagt taaacgtgaa ctgatgcaag gatcgctagc
      781 cagcttacgc caggccgcat ttccagttat cgccgctatt ggtgggatga ttgtgccggc
      841 attactctat ctggctttta actatgccga tccgattacc cgcgaagggt gggcgatccc
      901 ggcggctact gacattgctt ttgcacttgg tgtgctggcg ctattgggaa gtcgtgttcc
      961 gttagcgctg aagatctttt tgatggctct ggctattatc gacgatcttg gggccatcat
     1021 tatcatcgca ttgttctaca ctaatgactt atcgatggcc tctcttggcg tcgcggctgt
     1081 agcaattgcg gtactcgcgg tattgaatct gtgtggtgta cgccgcacgg gcgtctatat
     1141 tctggttggc gtggtgttgt ggactgcggt gttgaaatcg ggggttcacg caaccctggc
     1201 gggggtaatt gtcggcttct ttattccttt gaaagagaag catgggcgtt ctccagccaa
     1261 gcgactggag catgtgttgc acccgtgggt ggcgtatctg attttgccgc tgtttgcatt
     1321 tgctaatgct ggcgtttcac tgcaaggcgt cacgctggat ggcttgacct ccattctgcc
     1381 attggggatc atcgctggct tgctgattgg caaaccgctg gggattagtc tgttctgctg
     1441 gttggcgctg cgtttgaaac tggcgcatct gcctgaggga acgacttatc agcaaattat
     1501 ggcggtgggg atcctgtgcg gtatcggttt tactatgtct atctttattg ccagcctggc
     1561 ctttggtagc gtagatccag aactgattaa ctgggcgaaa ctcggtatcc tggtcggttc
     1621 tatctcttcg gcggtaattg gatacagctg gttacgcgtt cgtttgcgtc catcagtgtg
     1681 acaggacggt ttaccgggga gccataaacg gctccctttt cattgttatc agggagagaa
     1741 atgagcatgt ctcatatcaa ttacaaccac ttgtattact tctggcatgt ctataaagaa
     1801 ggttccgtgg ttggcgcagc ggaggcgctt tatttgacac cacaaaccat taccggacag
     1861 attcgggcgc tggaagagcg cctgcaaggc aaattattta agcgcaaggg acgtggtctc
     1921 gaacccagcg agctgggaga gctggtctat cgctatgccg ataaaatgtt caccttaagc
     1981 caggaaatgc tggatattgt gaactatcgc aaagaatcca atttattgtt tgacgttggc
     2041 gtggctgatg cactttccaa acgcctggtc agtagcgtac ttaacgccgc agtggtagaa
     2101 ggcgagccga ttcatcttcg ctgcttcgaa tccacccacg aaatgctgct ggaacaatta
     2161 agccagcata aactggatat gatcatttcc gactgtccga tagattctac gcagcaggaa
     2221 ggcctgttct ccgtgagaat tggcgaatgt ggcgtgagtt tctggtgtac aaatccacca
     2281 ccggaaaaac cgttcccggc ttgtctggaa gaacggcggc ttttgattcc tgggcgacgt
     2341 tcaatgttag ggcgcaaatt gcttaactgg tttaactccc agggattaaa cgtagaaatc
     2401 ctcggcgagt ttgatgatgc cgcgttgatg aaagcttttg gtgcgatgca caatgcaatc
     2461 ttcgttgccc caacgcttta tgcatatgac ttttatgccg ataaaactgt cgtagaaatt
     2521 ggtcgcgtcg aaaatgtgat ggaagagtac catgctattt ttgctgagcg gatgattcag
     2581 cacccggcgg tacagcgaat ctgcaatacg gattattctg cgctttttag cccagcggca
     2641 cgttaatcgg cagctccccc aaagttaagg tgggggagat agattagttg tacattacca
     2701 cgattttgac tcggctcatt attttcccgc ttgagacatt atttccatat gtacgcgggc
     2761 gaataaatag aggaatctga ttacttcctt catggggatg ctgaaaagag tagtaattgc
     2821 ttttaccata ctggatttca tgcgtaccat cattggagag ttgaaagcct atttgacccg
     2881 caccgtcctc actgttttct aaatcatttt ttaatatgct ggttcctgac tcctgtatca
     2941 tcactggctc aaagtaatat tcaacatcac tgggttcaaa aactaattca ccttgctcac
     3001 cctggataca gtcaaatctt atatgatgaa actgataatt ttcattattg atacgagaca
     3061 gtacaaatcg tccag
//
LOCUS       DAPOAV010000221         3066 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.226, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000221 DAPOAV010000000
VERSION     DAPOAV010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3066
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.226"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..659)
                     /gene="gloB"
                     /locus_tag="RN951_004559"
     CDS             complement(<1..659)
                     /gene="gloB"
                     /locus_tag="RN951_004559"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase"
                     /protein_id="HDX2529423.1"
                     /translation="MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAIAANNW
                     QPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEF
                     SVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTASQMYQSLKKLSALPDDTL
                     VCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLR
                     T"
     gene            693..1415
                     /locus_tag="RN951_004560"
     CDS             693..1415
                     /locus_tag="RN951_004560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414749.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDX2529424.1"
                     /translation="MKPARVPQTVVAPDCWGDLPWGKLYRKALERQLNPWFTKMYGFH
                     LLKIGNLSAEINCEACAVSHQVNVSAQGMPVQVQADPLHLPFADKSVDVCLLAHTLPW
                     CTDPHRLLREADRVLIDDGWLVISGFNPISFMGLRKLVPVLRKTSPYNSRMFTLMRQL
                     DWLSLLNFEVLHASRFHVLPWNKHGGKLLNAHIPALGCLQLIVARKRTIPLTLNPMKQ
                     SKNKPRIRQAVGATRQCRKPQA"
     gene            complement(1412..1879)
                     /gene="rnhA"
                     /locus_tag="RN951_004561"
     CDS             complement(1412..1879)
                     /gene="rnhA"
                     /locus_tag="RN951_004561"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI"
                     /protein_id="HDX2529425.1"
                     /translation="MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTN
                     NRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVD
                     LWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV"
     gene            1944..2675
                     /gene="dnaQ"
                     /locus_tag="RN951_004562"
     CDS             1944..2675
                     /gene="dnaQ"
                     /locus_tag="RN951_004562"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HDX2529426.1"
                     /translation="MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNRRLT
                     GNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPTFAEVADEFMDYIRGAELVIHNAAF
                     DIGFMDYEFSLLKRDIPKTNTFCKVTDSLAVARKMFPGKRNSLDALCARYEIDNSKRT
                     LHGALLDAQILAEVYLAMTGGQTSMAFAMEGETQQQQGEATIQRIVRQASKLRVVFAT
                     DEEIAAHEARLDLVQKKGGSCLWRA"
     gene            2808..2884
                     /locus_tag="RN951_004563"
     tRNA            2808..2884
                     /locus_tag="RN951_004563"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2842..2844,aa:Asp,seq:gtc)
BASE COUNT          778 a          718 c          729 g          841 t
ORIGIN      
        1 tccgttctta aaaaaacatt aatttgccgc tcatttttca gaattacggg tagtgttatt
       61 tgattttttg cccgtaactc cttaacttta cgataataat catttatgga caaatcgtgc
      121 ggaagaatac tcaaagcaaa cttcatattt gataaggtat attcatgagc acaacatacc
      181 aatgtatcgt caggtaacgc acttaacttt ttaagtgatt gatacatttg tgatgctgtc
      241 ccttcaaaca accgaccaca cccaccagaa aacagtgtgt cgccgcaaaa tagataaggt
      301 ttactgaagt aacagatatg tcctaaagtg tgacccggcg tagcaattac actaaattca
      361 tgccccaaaa cgaaggcagt ttcgccatct ttgactacct gtgttgttcc cttatcttgt
      421 gtctcttgtg gaccatacac cacaatttgt ggaaactttt ccaccagttc ttttacgccg
      481 ccaacgtgat cgtggtgatg gtgggtgaga aatatggcct ccggttgcca gttattggcg
      541 gcaatggcgt ttaatactgg ctctgcgtct ccgggatcga caatcaggca gcgacctgct
      601 tcatcattca aaacccagat gtaattgtca tcaaaggcgg gaatactgtt aagattcata
      661 gattacctct cagtgtgaaa cggaaggttg tgatgaaacc ggcaagagtc cctcaaactg
      721 tcgtggctcc tgattgctgg ggcgatttgc cctggggaaa gctttatcgc aaggcgctgg
      781 agcgccagct caacccgtgg ttcactaaaa tgtatggttt tcatctgctt aagattggca
      841 atttaagcgc agaaatcaat tgcgaagcgt gcgcggtttc tcatcaagtg aatgtttctg
      901 cgcaaggaat gcccgtccag gtacaggcgg acccacttca tcttcctttt gccgataaat
      961 ccgttgatgt ttgtctactg gcacatacat tgccgtggtg caccgatccg catcgtttat
     1021 tgcgtgaagc cgatcgggta ttgattgatg atggctggct ggtcattagt ggcttcaatc
     1081 ccatcagttt tatgggatta cgcaaacttg tgccggtatt gcgcaaaacc tcgccctata
     1141 acagccggat gtttactctg atgcggcagc tggactggct ctctttgttg aattttgaag
     1201 tgctacacgc cagccgtttc cacgttctcc cgtggaacaa acacggagga aaactattga
     1261 atgcgcatat tcctgcgctt ggttgcttac aacttattgt tgcccggaaa cggactattc
     1321 ctttaacgct aaatccgatg aaacagagta aaaacaagcc acgaattcgc caggcggttg
     1381 gagccacccg gcaatgtcgt aaaccacagg cttaaacttc aacttggtag cctgtatctt
     1441 ccagtgtggg attcatcgcc gcggcacgag ccagttcatc acagcgttcg ttttccgggt
     1501 gtccggcatg gcctttaacc cattcccatt tgatttgatg ctgccccaat gcagcatcaa
     1561 gacgttgcca gagatcgaca ttttttactg gttttttgtc tgcggttttc cagccacgtt
     1621 ttttccagtt atggatccac tgggtgatac cctggcggac atactggctg tcggtactca
     1681 aaatgacttc gcaatgttct tttaacgcct ccagcgcgac aatagcggcc atcaactcca
     1741 tacggttgtt ggtggtgcgg gtgtagccag cgctaaaggt tttctcgcgt ccgcgatagc
     1801 gtaaaatagc gccgtaaccc ccaggtcctg gattgcccag acacgaacca tcggtgaaaa
     1861 tttctacctg tttaagcatc tctggtagac ttcctgtaat tgaatcgaac tgtaaaacga
     1921 caagtctgac ataaatgacc gctatgagca ctgcaattac acgccagatc gttctcgata
     1981 ccgaaaccac cggtatgaac cagattggtg cgcactatga aggccacaag atcattgaga
     2041 ttggtgccgt tgaagtggtg aaccgtcgcc tgacgggcaa taacttccat gtttatctca
     2101 aacccgatcg gctggtggat ccggaagcct ttggcgtaca tggtattgcc gatgaatttt
     2161 tgctcgataa gcccacgttt gccgaagtag ccgatgagtt catggactat attcgcggcg
     2221 cggagttggt gatccataac gcagcgttcg atatcggctt tatggactac gagttttcgt
     2281 tgcttaagcg cgatattccg aagaccaata ctttctgtaa ggtcaccgat agccttgcgg
     2341 tggcgaggaa aatgtttccc ggtaagcgca acagcctcga tgcgttatgt gctcgctacg
     2401 aaatagataa cagtaaacga acgctgcacg gggcattact cgatgcccag atccttgcgg
     2461 aagtatatct ggcgatgacc ggtggtcaaa cgtcgatggc ttttgcgatg gaaggagaga
     2521 cacaacagca acaaggtgaa gcaacaattc agcgcattgt acgtcaggca agtaagttac
     2581 gcgttgtttt tgcgacagat gaagagattg cagctcatga agcccgtctc gatctggtgc
     2641 agaagaaagg cggaagttgc ctctggcgag cataaatacc tgtgaaaggc gctaaaaata
     2701 gcgacttggg cgatttttgc agcaaacgat tcaaaagatg agaaaaaccg ttgacgaagg
     2761 tcgaggcaat ccgtaatatt cgcctcgttc ccaacggaac acaacgcgga gcggtagttc
     2821 agtcggttag aatacctgcc tgtcacgcag ggggtcgcgg gttcgagtcc cgtccgttcc
     2881 gccactattc actcatgaaa atgagttcag agagccgcaa gatttttaat tttgcggttt
     2941 ttttgtattt gaattccacc atttctctgt tcaatgattt tactctggcg taggtgcgtg
     3001 attctcgctt gttgtctcat tcattaaaat tcaataatga tatcgaacca ttcagcttaa
     3061 atatat
//
LOCUS       DAPOAV010000222         2947 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.227, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000222 DAPOAV010000000
VERSION     DAPOAV010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2947
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.227"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..458)
                     /locus_tag="RN951_004564"
     CDS             complement(<1..458)
                     /locus_tag="RN951_004564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308587.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529427.1"
                     /translation="MSGKPAARQGDMTQYGGPIVQGSAGVRIGAPTGVACSVCPGGMT
                     SGNPVNPLLGAKVLPGETDLALPGPLPFILSRTYSSYRTRTPAPVGVFGPGWKAPSDI
                     RLQLRDDALVLNDNGGRSIHFEPLLPGEAVYSRSESMWLVRGGKAAQPDG"
     gene            complement(525..2633)
                     /locus_tag="RN951_004565"
     CDS             complement(525..2633)
                     /locus_tag="RN951_004565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HDX2529428.1"
                     /translation="MSTGLRFTLEVDGLPPDAFAVVSFHLNQSLSSLFSLDLSLVSQQ
                     FLSLEFAQVLDKMAYLTIWQGDEVQRRVKGVVTWFELGENDKNQMLYSMKVHPPLWRA
                     GLRQNFRIFQNEDIKSILGTMLQENGVTEWSPLFSEPHPSREFCVQYGETDYDFLCRM
                     AAEEGIFFYEEHAYKSTDQSLVLCDTVRHLPESFEIPWNPNTRTEVSTLCISQFRYSA
                     QIRPSSVVTKDYTFKRPGWAGRFEQEGQHQDYQRTQYEVYDYPGRFKGAHGQNFARWQ
                     MDGWRNNAETARGMSRSPEIWPGRRIVLTGHPQANLNREWQVVASELHGEQPQAVPGR
                     QGAGTALENHFAVIPADRTWRPQPLLKPLVDGPQSAVVTGPAGEEIFCDEHGRVRVKF
                     NWDRYNPSNQDSSCWIRVAQAWAGTGFGNLAIPRVGQEVIVDFLNGDPDQPIIMGRTY
                     HHENRTPGSLPGTKTQMTIRSKTYKGSGFNELKFDDATGKEQVYIHAQKNMNTEVLNN
                     RTTDVINNHAETIGNNQMIAVTNNQIQTVGVNQIETVGSNQIIKVGSIQVETIGLVRA
                     LTVGVAYQTTVGGIMNTSVALMQSSQIGLHKSLRVGLGYDVKVGNNVTFTVGKTKKDD
                     TGQTAIYSAGEHLELCCGKARLVLTKDGQIFLNGTKIHLQGKEQVNGDSLLINWNCAA
                     SKSPPKTPDEKQDTPDMREY"
BASE COUNT          620 a          862 c          755 g          710 t
ORIGIN      
        1 tggccgtccg gctgcgctgc cttaccaccg cgcaccagcc acattgactc gctgcggctg
       61 tacaccgcct cccccggcag cagcggctca aagtgaatgc tccgcccgcc gttgtcgttg
      121 agtaccagtg catcatcgcg tagctgtaag cggatatcag aaggcgcttt ccagccgggg
      181 ccaaacactc ccaccggcgc gggtgtcctg gtccggtagc tgctgtaggt gcgggagaga
      241 atgaacggca gcgggccggg cagcgcaagg tccgtctcgc cgggcagcac cttcgccccc
      301 agcagcggat ttaccgggtt gcccgaagtc atcccgcccg gacacaccga gcacgccacg
      361 ccggtgggcg cgccaattct tacacctgcc gaaccctgga caatgggacc gccatactga
      421 gtcatatctc cctgacgcgc cgctggtttt ccgctcatga ttcaattcct tcttctgttt
      481 atttttaatg ctggtttgtt actgaatacc gaacaggtac gggatcagta ctctctcata
      541 tccggcgtat cctgcttttc atcaggggtc ttcggtgggg atttcgaggc tgcacagttc
      601 cagttaatca acagtgagtc accattaacc tgctccttac cctgcaaatg aatttttgtg
      661 ccgttgagaa aaatttgtcc gtccttcgtc agcaccagcc ttgccttacc acagcagagc
      721 tccagatgct caccggcgga gtaaatcgcg gtctgcccgg tatcatcctt tttcgtttta
      781 ccaacggtga aggtaacgtt atttccgact ttgacgtcat aacccagccc gaccctcaac
      841 gatttatgca aaccgatctg cgaggactgc atcagagcca ccgaagtgtt cataatgcca
      901 cctaccgtcg tctggtacgc cacgcccacg gtcagcgcac gaacaagtcc aatcgtttcc
      961 acctgaatag aacccacttt aattatctgg ttactgccca ccgtctctat ctggttgaca
     1021 cccaccgtct gtatctgatt gttggtaacc gcaatcatct gattgttgcc aatggtttca
     1081 gcatggttgt ttatcacatc agtggtgcgg ttattcagca cctcggtgtt catgttcttc
     1141 tgcgcgtgga tgtagacctg ttctttccct gtcgcatcgt caaacttcag ttcattaaac
     1201 ccgctgccct tataggtttt cgaacgaatg gtcatctgcg tcttcgtccc cggcaggctg
     1261 ccgggtgtgc ggttttcatg gtggtaggta cgccccataa taatcggctg gtccgggtcg
     1321 ccgttgagga agtccacaat cacctcctga cccactcgcg gtatcgccag gttgccaaag
     1381 ccggtgcctg cccacgcctg tgccacacgg atccagcatg aactgtcctg gtttgacggg
     1441 ttatagcggt cccagttaaa tttcacccgc acgcggccat gttcatcaca gaagatttcc
     1501 tcgcctgccg gtcccgtcac gacggcgctc tgcgggccgt cgaccagcgg tttcagcaac
     1561 ggctgtggtc gccatgttct gtctgccggg atcaccgcaa aatggttctc cagcgccgtc
     1621 cccgctccct gccgtcctgg caccgcctgt ggctgttcgc cgtgcagttc acttgccacc
     1681 acctgccatt cccggttcag gttcgcctgc ggatgccccg tcagcacaat tcgtcgtccc
     1741 ggccatatct ccggcgagcg actcattccc cgcgcggttt ctgcattgtt tcgccagccg
     1801 tccatctgcc agcgggcaaa gttctgcccg tgggcaccct tgaaacgtcc ggggtagtca
     1861 tacacttcat actgcgtgcg ctggtagtcc tggtgctggc cttcctgttc aaaacgtccg
     1921 gcccagccgg ggcgtttaaa ggtgtagtct ttggtcacca cggaagaagg gcggatttgt
     1981 gcgctgtagc ggaactggct gatgcagagg gtgctcacct cggtacgggt gttcgggttc
     2041 catgggattt caaaagattc gggcagatgg cggactgtgt cgcacagcac caggctctgg
     2101 tcggtacttt tgtaagcatg ctcctcataa aagaagatgc cttcctccgc cgccatccgg
     2161 cacaggaaat cgtaatcagt ctcaccgtac tggacacaaa actcacggga aggatgcggc
     2221 tcgctgaaca gcggactcca ttcggtcacc ccgttttcct gcaacatcgt gccgaggatg
     2281 cttttgatgt cctcgttctg gaagatacgg aagttctggc gcagaccggc acgccacagc
     2341 ggcgggtgca ccttcatgct gtacagcatc tggtttttgt cgttctcccc gagttcaaac
     2401 caggtcacca cgcctttcac ccggcgctgt acttcatcgc cctgccatat cgtcaggtag
     2461 gccattttgt ccagcacctg cgcaaattca agggagagaa actgctggct gaccagggag
     2521 agatcgaggg aaaagagcga agagagtgac tggttcagat gaaaggaaac caccgcaaaa
     2581 gcatccggcg gcaggccgtc cacttccagt gtgaaacgta atccggttga catagcaacc
     2641 tccgtgaaaa tgaataataa tccgcacata ttgcatgtac aacatgtcgg gcggatgaga
     2701 taagcgagtc gacatctggc gttaccgggg aatatcagaa aaatgtcatg gttatgtgat
     2761 gatttagtct gggattttac ttcagagaaa cgggtgtctg tttagtcaac aaaataatca
     2821 caaacgcaac ggatgggttc tcgacgttat tcacgacagg ctcgtacatt acagcgagta
     2881 ataaaaaacc tgatatgcaa agtcaaacca atattcataa tgtcttttta ttcacaacaa
     2941 taaataa
//
LOCUS       DAPOAV010000223         2897 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.228, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000223 DAPOAV010000000
VERSION     DAPOAV010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2897
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.228"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            1..1602
                     /gene="espL1"
                     /locus_tag="RN951_004566"
                     /pseudo
     CDS             1..1602
                     /gene="espL1"
                     /locus_tag="RN951_004566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310454.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="type III secretion system effector EspL1"
     gene            1774..1881
                     /locus_tag="RN951_004567"
     CDS             1774..1881
                     /locus_tag="RN951_004567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588455.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529429.1"
                     /translation="MPTKRFDKKHWKMVVVLLAICGAMLLLRWAAMIWG"
     gene            complement(1934..2692)
                     /locus_tag="RN951_004568"
     CDS             complement(1934..2692)
                     /locus_tag="RN951_004568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiY family protein"
                     /protein_id="HDX2529430.1"
                     /translation="MKLLKTVPAIVMLAGGMFASLNAAADDSVFTVMDDPASAKKPFE
                     GNLNAGYLAQSGNTKSSSLTADTTMTWYGHTTAWSLWGNASNTSSNDERSSEKYAAGG
                     RSRFNLTDYDYLFGQASWLTDRYNGYRERDVLTAGYGRQFLNGPVHSFRFEFGPGVRY
                     DKYTDNASETQPLGYASGAYAWQLTDNAKFTQGVSVFGAEDTTLNSESALNVAINEHF
                     GLKVAYNVTWNSEPPESAPEHTDRRTTLSLGYSM"
BASE COUNT          876 a          633 c          586 g          802 t
ORIGIN      
        1 aaatcatttc cttattactg gaaaccacgc ctattaaagc taaccatttg cgaagcatac
       61 tggattatat tgaacaggaa cagttaactg ctgaagatcg taaccattgt atgaaactgt
      121 ctaaaaaaat ccatagagaa aaaaactata cacccaacag taaatctcaa tggtagtgca
      181 tgttttttgc aatctccttc tgacgctatt ttttgtcgcc atctgtcatt gcaatacgcc
      241 cttgattcat tgagaaatgg aaaaggcaaa gtcaacctga ttaaacatta ctcctccgtt
      301 gaatccatac agcagcatgt ccccttagtc cgggacgcgg agttcagagc attacttcgc
      361 catcctcctg cagggagtcg cgttatcgcg agtaaggatt ttggcttcgc tttagatatt
      421 ttcttttgtc gaatgatggc aaacaatgtc agtcatatgt ccgcgatttt atatatagac
      481 aatcatactt tgtcagtaag gctacgaata aagcagtcag tgtatggaca attaaattat
      541 gttgtgtccg tttacgaccc gaacgatacc aacgttgccg tcagagacac ccacaggaca
      601 gcacggggct ttctttcgct tgataagttc atcagttcag gtcccgatgc tcagacctgg
      661 gctgatagat atgttcgcaa ctgtgcaatt gctattctgc ccctattacc tgtgggagtt
      721 ccaggggcta ttttcgcggg tattgcatca cgaatgccat ttgcccctat acatccatcg
      781 gcaatgttgt taataatggc tacaggccag actcaacagc ttattacatt attcaaacag
      841 ttgcccatac tccctgaaaa agaaatcatt gaaataataa ctgcgcagaa tagcgttggt
      901 acacctgctt tatttttggc tatgatgaac ggacatactg acaacgtgaa aatatttatg
      961 caagaaattc agtcactggt agataatcac atcattcatg aagataatct ggttaaatta
     1021 ctgcaaacta aaagtgctaa cgaaacacct ggactttata tctccatgtt gtatggattc
     1081 gatgaaataa tcgatatctt tctgaatgca ttaaccactc caatagcaca agagctttta
     1141 aacaaaaaac tggtgatgag tattttagcc atgaaaatac atgatggtga gccaggatta
     1201 tacgccgcaa tggaaaataa tcaccctttg tgtgtcacac ggttcctctc taaaattaat
     1261 ggcatcgcct ttaaatacaa gttgagcaaa gctaacatca tggatttatt aaaaggagct
     1321 acagcacagg gaacccctgc attatacatc gccatgagca agggtaatga agacgtcgtg
     1381 ttatcttata tatcgacgct gggtgctttt gcaaaaaaac attcttttag tcaacatcag
     1441 ttatttacac tattggccgc taaaaatcat gacaacatgt cagctgttca tatagccatt
     1501 catcataagc attataaaac tgtagaaaca tattatgctg ctattaatgc aatcagccaa
     1561 agcctgagtt ttagtgctga tgaaataaag acgtatttat aaccagctat ttacgatata
     1621 tatcgataca taattttatt tttttcataa aacgcagaaa cagtgaccat gtgcacaacg
     1681 ccacccgacg gctgtaataa caaaaaatcc cttgatgcct gtcccttttg ttacactccg
     1741 ttatcacgca caagagatat gcaggacact ggtatgccga ctaaacgctt tgataaaaaa
     1801 cactggaaga tggtggtggt gctactggca atctgtggcg ctatgttgtt gctacgttgg
     1861 gcagcaatga tttggggctg agcagtgaca aacgaagaca gccagaccgc ataacacggt
     1921 ccggcagata attttacatg ctgtagccca gcgataaggt tgtccgacgg tcggtatgtt
     1981 ccggtgcaga ctctggaggt tcagagttcc atgtgacgtt gtaagccacc ttcagtccaa
     2041 aatgttcatt aatagcaaca tttaatgcgc tttcggagtt cagcgttgtg tcttccgcgc
     2101 caaagaccga aacaccctgc gtaaatttag cgttgtcagt caactgccat gcataagccc
     2161 cggaggcata gcccagcggc tgggtttcac tggcattgtc ggtatatttg tcgtaacgca
     2221 cacctggacc gaattcaaag cggaaactgt gtaccgggcc attcaaaaac tgacgaccat
     2281 aacccgcggt caacacatcg cgctctcgat agccgttata acggtctgtc agccagcttg
     2341 cctgaccaaa taaatagtca taatcagtta aattaaaacg gctacgcccg cccgccgcat
     2401 atttttctga agaacgctca tcattagaag aagtattact ggcgttcccc cacagcgacc
     2461 aggcagtggt gtgtccatac caggtcatgg tggtgtcagc cgtaagtgag gagcttttcg
     2521 tattgcctga ttgtgcaaga tatcctgcgt tcagattacc ttcgaaaggt tttttagcgc
     2581 tggcaggatc atccatgaca gtaaaaacgg aatcatcggc agctgcattc agtgacgcaa
     2641 acatgccccc cgccaacata acgatggcag gaactgtctt caaaagcttc atttatcaag
     2701 agtccgtaca acaaaaaaag agaccatcgc ggtcccggaa actttcttaa ggatcaaaga
     2761 ttagcgtccc tggaaaggta acgaattata aaaaggcgcg aataacttag caatgtattc
     2821 ttatttcatt ttttgaataa gcatgtggcg aaaacagatt tttatttata tatatttatc
     2881 tgcaaaattt taaataa
//
LOCUS       DAPOAV010000224         2855 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.229, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000224 DAPOAV010000000
VERSION     DAPOAV010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2855
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.229"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..360
                     /locus_tag="RN951_004569"
     CDS             <1..360
                     /locus_tag="RN951_004569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HDX2529431.1"
                     /translation="LDRLESEILADRVSEESRRWLASCGLTVEQMQNQMDPVYTPARK
                     IHLYHCDHRGLPLALVSTEGATEWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEES
                     GLYYNRHRALLNKSDFG"
     gene            complement(386..1354)
                     /locus_tag="RN951_004570"
     CDS             complement(386..1354)
                     /locus_tag="RN951_004570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS903B family transposase"
                     /protein_id="HDX2529432.1"
                     /translation="MKDQITHLPDNADRSVAKQKFKITNWPTYNKALINRGSITFWLD
                     DEAIQAWYESATPSSRGRPQRYSDLAITTVLVIKRVFRLTLRAAQGFIDSIFSLMNVP
                     LRCPDYSCVSRRAKSVNVSFKTPTRGEIAHLVIDSTGLKVFGEGEWKVKKHGQERRRI
                     WRKLHLAVDSKTHEIICADLSLNNVTDSEAFPGLIRQTHRKIRSAAADGAYDTRLCHD
                     ELRRKKISALIPPRKGAGYWPGEYADRNRAVANQRMTGSNARWKWTTDYNRRSIAETA
                     MYRVKQLFGGSLTLRDYDGQVAEAMALVRALNKMTKAGMPESVRIA"
     gene            1409..1972
                     /locus_tag="RN951_004571"
     CDS             1409..1972
                     /locus_tag="RN951_004571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HDX2529433.1"
                     /translation="MQGRYITQDPIGLKGGWNFYQYPLNPVQYIDSMGLASKYGHLNN
                     GGYGARPNKPPTPDPSKLPDIAKQLRLPYPIDQASSAPNVFKTFFRALSPYDYTLYCR
                     KWVKPNLTCTPQDDSQYPGMDTKTASDYLPQTNWPTTQLPPGYTCAEPYLFPDINKPD
                     GPATAGIDDLGEILAKMKQRTSRGIRK"
     gene            1969..2538
                     /locus_tag="RN951_004572"
     CDS             1969..2538
                     /locus_tag="RN951_004572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529434.1"
                     /translation="MKRVLFFLLMIFVSFGVIADCEIQAKDHDCFTIFAKGTIFSAFP
                     VLNNKAMWRWYQNEDIGEYYWQTELGTCKNNKFTPSGARLLIRVGSLRLNENHAIKGT
                     LQELINTAEKTAFLGDRFRSYIRAGIYQKKSSDPVQLLAVLDNSIMVKYFKDEKPTYA
                     RMTAHLPNKNESYECLIKIQHELIRSEEK"
     gene            2764..>2855
                     /locus_tag="RN951_004573"
     CDS             2764..>2855
                     /locus_tag="RN951_004573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDX2529435.1"
                     /translation="MELKKLMEHISITPDYRQAWKVVHKLSDILL"
BASE COUNT          803 a          637 c          688 g          727 t
ORIGIN      
        1 ctcgaccggc tggaaagtga aatcctggct gaccgggtga gtgaggaaag ccgccgctgg
       61 ctggcatcgt gcggcctgac ggtggagcag atgcaaaacc agatggaccc ggtgtacacg
      121 ccggcgcgaa aaatccacct gtaccactgc gaccatcgcg gcctgccgct ggcgcttgtc
      181 agcacggaag gggcaacaga atggtgcgca gaatacgatg aatggggcaa cctgctgaat
      241 gaagagaacc cgcatcagct gcagcagctt atccgcctgc cggggcagca gtatgatgag
      301 gagtccggcc tgtattacaa ccgccaccgg gctttgttga ataaatcaga tttcgggtaa
      361 gtctcccccg tagcgggttg tgttttcagg caatacgcac gctttcaggc atacctgctt
      421 tcgtcatttt gttcagcgct cgtaccaggg ccatagcctc cgcaacctga ccatcgtagt
      481 cacgcagcgt cagtgaaccc ccgaacagct gttttacccg gtacatcgcc gtttccgcta
      541 tcgagcgacg gttgtaatct gttgtccatt tccaccgcgc attactcccg gtcattcgct
      601 gattagccac tgcacggtta cggtctgcat attcaccggg ccagtaaccc gcaccttttc
      661 ggggtgggat aagcgcgctg attttcttac gtcgcagttc atcgtgacag agccgggtat
      721 cgtaagcgcc atcggcggcg gctgacctga ttttccggtg ggtttgccgg attaacccgg
      781 ggaaggcctc tgagtccgta acgttgttca gcgacaggtc agcgcagatg atttcatgtg
      841 ttttactgtc aacggcgaga tgcagcttac gccagatacg gcggcgttcc tggccatgct
      901 ttttgacttt ccactcgcct tcaccgaaga ccttcagccc ggtggaatca attaccaggt
      961 gtgcgatttc accccgggtg ggcgttttga aactgacatt aaccgacttt gcccgcctgc
     1021 tgacacagct gtaatccggg cagcgtagcg gaacgttcat cagagaaaaa atggaatcaa
     1081 taaaaccctg tgcagcccgc agggtcaacc tgaacacgcg tttaatgacc agaacggtgg
     1141 tgatggcaag gtcagaatag cgctgaggtc tgcctcgtga agaaggtgtt gctgactcat
     1201 accaggcctg aatagcttca tcatccagcc agaaagttat ggagccacgg ttgatgaggg
     1261 ctttattgta ggtgggccag ttggtgattt tgaacttttg ctttgccacg gaacggtctg
     1321 cgttgtcggg aagatgcgtg atctgatcct tcaactcagc aaaagttcga tttattcaac
     1381 aaagccccgc caccgctatt atgacccgct gcaggggagg tatatcactc aggatccgat
     1441 tgggctgaag gggggatgga atttttatca gtatccgctg aatccggttc agtatataga
     1501 ttcaatggga ctggcatcaa aatatggaca cttaaataat ggcggatatg gagcgagacc
     1561 caacaaaccg cctacgcccg atccaagtaa attgccggac atagcgaaac aattaagact
     1621 gccatatcct attgaccagg ccagtagtgc gcctaatgtt ttcaaaacat tcttcagagc
     1681 attaagccct tacgactaca cactgtattg caggaagtgg gtaaaaccaa atctgacttg
     1741 tacgccacag gatgattccc agtatccagg gatggataca aagacagcaa gtgattacct
     1801 gccacagaca aattggccaa caactcaatt accaccagga tatacttgtg cagaacccta
     1861 tttattccca gacattaata aacccgatgg gccagcaaca gcagggatag atgatttggg
     1921 tgaaatttta gctaagatga aacagagaac atcgagagga ataagaaaat gaaaagagtt
     1981 ttgttctttt tgctgatgat atttgttagt tttggtgtta tagctgattg cgaaatacaa
     2041 gctaaagatc atgattgttt tactattttc gctaagggta ctattttttc cgcgtttcct
     2101 gtcttaaata ataaagccat gtggagatgg tatcagaatg aggacatcgg tgagtattat
     2161 tggcaaacag aactgggtac atgtaaaaat aataaattca caccaagcgg ggcgagactc
     2221 ttaattcgcg tcgggtcact acgccttaat gaaaatcatg ccatcaaagg aacgttgcag
     2281 gagttgataa atacagcaga aaaaacggcg tttctcggcg atcggtttag aagttatata
     2341 agagcgggta tctatcaaaa aaagagcagt gatccagttc agttgttggc agtccttgat
     2401 aattcaatca tggtaaaata ttttaaagat gagaaaccaa cttatgctcg aatgacagca
     2461 catctcccga acaaaaatga gtcttacgaa tgtttaataa agatacagca tgaactaatt
     2521 cgtagtgaag agaaataaaa tctcttcctg agaaaacaaa ttaatcattg tgaaaaatta
     2581 tataactcat ggaataggtg tttattttgc gttccatttg cagggaaaga tcacgtaacg
     2641 ctactttttt gtactaaata attcgaattt taagttcaac aattgagata ctacttattg
     2701 tctaaagctg tttttcatag cttatacatg atcaaatact ccttacataa ataaggtgaa
     2761 caaatggaac ttaaaaaatt gatggaacat atttctatta cacccgatta cagacaagcc
     2821 tggaaagtgg tgcataaatt gtcagatatt ctact
//
LOCUS       DAPOAV010000225         2824 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.230, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000225 DAPOAV010000000
VERSION     DAPOAV010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2824
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.230"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            30..1649
                     /locus_tag="RN951_004574"
     CDS             30..1649
                     /locus_tag="RN951_004574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001460945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase"
                     /protein_id="HDX2529436.1"
                     /translation="MAAFAAHAADDVKLKATKTNVAFSDFTPTEYSTKGKPNIIVLTM
                     DDLGYGQLPFDKGSFDPKTMENREVVDTYKIGIDKAIEAAQKSTPTLLSLMDEGVRFT
                     NGYVAHGVSGPSRAAIMTGRAPARFGVYSNTDAQDGIPLTETFLPELFQNHGYYTAAV
                     GKWHLSKISNVPVPEDKQTRDYHDNFTTFSAEEWQPQNRGFDYFMGFHAAGTAYYNSP
                     SLFKNRERVPAKGYISDQLTDEAIGVVDRAKTLDQPFMLYLAYNAPHLPNDNPAPDQY
                     QKQFNTGSQTADNYYASVYSVDQGVKRILEQLKKNGQYDNTIILFTSDNGAVIDGPLP
                     LNGAQKGYKSQTYPGGTHTPMFMWWKGKLQPGNYDKLISAMDFYPTALDAADISIPKD
                     LKLDGVSLLPWLQDKKQGEPHKNLTWITSYSHWFDEENIPFWDNYHKFVRHQSDDYPH
                     NPNTEDLSQFSYTVRNNDYSLVYTVENNQLGLYKLTDLQQKDNLAAANPQVVKEMQGV
                     VREFIDSSQPPLSEVNQEKFNNIKKALSEAK"
     gene            1701..>2824
                     /locus_tag="RN951_004575"
     CDS             1701..>2824
                     /locus_tag="RN951_004575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416014.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HDX2529437.1"
                     /translation="MHVTAKPSSFQCNLKCDYCFYLEKESQFTHEKWMDDSTLKEFIK
                     QYIAASGNQVYFTWQGGEPTLAGLDFFRKVIHYQQRYAGQKRIFNALQTNGILLNNEW
                     CAFLKEHEFLVGISIDGPQELHDRYRRSNSGNGTFAKVIAAIERLKSYQVEFNTLTVI
                     NNVNVHYPLEVYHFLKSIGSKHMQFIELLETGTPNIDFSGHSENTFRIIDFSVPPTAY
                     GKFMSTIFMQWVKNDVGEIFIRQFESFVSRFLGNGHTSCIFQESCKDNLVVESNGDIY
                     ECDHFVYPQYKIGNINKSELKTMNSVQLTAQKKRIPAKCQQCAYKPICNGGCPKHRIT
                     KVNNETVSYFCEGYKILFSTMVPYMNAMVELAKNRVPLYH"
BASE COUNT          858 a          617 c          580 g          769 t
ORIGIN      
        1 cctcgatatc tttgatactg gcatctggta tggctgcatt tgctgctcat gcggcagatg
       61 atgtaaagct gaaagcaacc aaaacaaacg ttgctttctc agactttacg ccgacagaat
      121 acagtaccaa aggaaagcca aatattatcg tactgaccat ggatgatctt ggttatggac
      181 aacttccttt tgataaggga tcttttgacc caaaaacaat ggaaaatcgt gaagttgtcg
      241 atacctacaa aatagggata gataaagcca ttgaagctgc acaaaaatca acgccgacgc
      301 tcctttcatt aatggatgaa ggcgtacgtt ttactaacgg ctatgtggca cacggtgttt
      361 ccggcccctc ccgcgccgca ataatgaccg gtcgagctcc cgcccgcttt ggtgtctatt
      421 ccaataccga tgctcaggat ggtattccgc taacagaaac tttcttgcct gaattattcc
      481 agaatcatgg ttattacact gcagcagtag gtaaatggca cttgtcaaaa atcagtaatg
      541 tgccggtacc ggaagataaa caaacgcgtg actatcatga caacttcacc acattttctg
      601 cggaagaatg gcaacctcaa aaccgtggct ttgattactt tatgggattc cacgctgcag
      661 gaacggcata ttacaactcc ccttcactgt tcaaaaatcg tgaacgtgtc cccgcaaaag
      721 gttatatcag cgatcagtta accgatgagg caattggcgt tgttgatcgt gccaaaacac
      781 ttgaccagcc ttttatgctt tacctggctt ataatgctcc gcacctgcca aatgataatc
      841 ctgcaccgga tcaatatcag aagcaattta ataccggtag tcaaacagca gataactact
      901 acgcttccgt ttattctgtt gatcagggtg taaaacgcat tctcgaacaa ctgaagaaaa
      961 acggacagta tgacaataca attattctct ttacctccga taatggtgcg gttatcgatg
     1021 gtcctctgcc gctgaacggg gcgcaaaaag gctataagag tcagacctat cctggcggta
     1081 ctcacacccc aatgtttatg tggtggaaag gaaaacttca acccggtaat tatgacaagc
     1141 tgatttccgc aatggatttc tacccgacag ctcttgatgc agccgatatc agcattccaa
     1201 aagaccttaa gctggatggc gtttccttgc tgccctggtt gcaagataag aaacaaggcg
     1261 agccacataa aaatctgacc tggataacct cttattctca ctggtttgac gaggaaaata
     1321 ttccattctg ggataattac cacaaatttg ttcgccatca gtcagacgat tacccgcata
     1381 accccaacac tgaggactta agccaattct cttatacggt gagaaataac gattattcgc
     1441 ttgtctatac agtagaaaac aatcagttag gtctctacaa actgacggat ctacagcaaa
     1501 aagataacct tgccgccgcc aatccgcagg tcgttaaaga gatgcaaggc gtggtaagag
     1561 agtttatcga cagcagccag ccaccgctta gcgaggtaaa tcaggagaag tttaacaata
     1621 tcaagaaagc actaagcgaa gcgaaataac taaaccttca tgcggcggat ttttccgccg
     1681 ccttattgag cgagatagcg atgcacgtta cagccaagcc ctccagtttt caatgtaatc
     1741 tcaaatgtga ttactgtttt taccttgaaa aagagtcgca gtttactcat gaaaaatgga
     1801 tggatgacag cactctgaaa gagttcatca aacaatatat cgcagcgtct ggcaatcagg
     1861 tctattttac ctggcaaggc ggtgaaccca ctctggctgg cctggatttt ttccgtaaag
     1921 ttattcacta tcaacaacgc tatgcaggcc aaaaacgtat ttttaatgca ttacaaacga
     1981 atggcatttt attgaataat gaatggtgtg cctttctcaa agaacatgaa tttctggttg
     2041 gtatctcgat cgatggcccc caggagttac atgaccgtta cagacgcagt aattcaggta
     2101 acggtacttt tgcaaaagtg atagcagcca tcgagcgtct gaaatcatat caagtagagt
     2161 ttaatacgtt aaccgtcatt aataacgtta atgtccatta ccctcttgag gtttatcatt
     2221 ttttaaaatc tatcggcagt aaacatatgc aatttatcga attgctagaa accgggacgc
     2281 cgaatattga tttcagtggt catagtgaga acacattccg tatcattgat ttttctgtgc
     2341 ctcccacggc ttatggcaag tttatgtcaa ccatttttat gcaatgggtt aaaaacgatg
     2401 tgggtgaaat tttcatccgt cagtttgaaa gctttgtcag ccgttttttg gggaatgggc
     2461 ataccagttg tattttccag gagtcctgca aggataatct ggttgttgaa agtaatggag
     2521 acatttacga atgcgaccat tttgtctatc cacagtacaa aattggaaac attaataaat
     2581 ctgaactcaa aacgatgaac agtgtacaac tgacagcgca aaaaaaacgg attccagcga
     2641 aatgtcagca atgtgcatat aaacctatct gcaatggcgg ttgtcctaag catcgtatta
     2701 ctaaagtaaa caatgagact gtttcttatt tttgcgaagg ttataaaatc cttttttcaa
     2761 ccatggtacc ttatatgaac gccatggtag agttagctaa gaacagagta ccgctttacc
     2821 acat
//
LOCUS       DAPOAV010000226         2803 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.231, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000226 DAPOAV010000000
VERSION     DAPOAV010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2803
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.231"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(1..70)
                     /locus_tag="RN951_004576"
                     /pseudo
     CDS             complement(1..70)
                     /locus_tag="RN951_004576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            125..802
                     /locus_tag="RN951_004577"
     CDS             125..802
                     /locus_tag="RN951_004577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HDX2529438.1"
                     /translation="MSIIFNGHYRMKHRTWITEALRLHFEEHLPRVVAGRRLGVPKST
                     VCSMFVRFRRAGLSWPLPAGMSEQELDACLYGQFSTVPVVRPESTVISEAPVVKKRPR
                     RPNFPYEFKIALVEQSLQPGACVAQIARENGINDNLLFNWRHQYRKGGLLPSGKNMPA
                     LLPVTLTPEPDNKIPAPAQEPEQINTPSDSLCCELVLPAGTLRLKGKLTPALLQTLIR
                     EIKGSSH"
     gene            802..1149
                     /gene="tnpB"
                     /locus_tag="RN951_004578"
     CDS             802..1149
                     /gene="tnpB"
                     /locus_tag="RN951_004578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDX2529439.1"
                     /translation="MISLPAGSRIWLVAGITDMRNGFNGLASKVQNVLKDDPFSGHLF
                     IFRGRRGDQIKVLWADSDGLCLFTKRLERGRFVWPVTRDGKVHLTPAQLSMLLEGINW
                     KHPKRTERAGIRI"
     gene            1169..2740
                     /locus_tag="RN951_004579"
     CDS             1169..2740
                     /locus_tag="RN951_004579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HDX2529440.1"
                     /translation="MDTSLAHENARLRALLQTQQDTIRQMAEYNRLLSQRVAAYASEI
                     NRLKALVAKLQRMQFGKSSEKLRAKTERQIQEAQERISALQEEMAETLGEQYDPVLPS
                     ALRQSSARKPLPASLPRETRVIRPEEECCPACGGELSSLGCDVSEQLELISSAFKVIE
                     TQRPKQACCRCDHIVQAPVPSKPIARSYAGAGLLAHVVTGKYADHLPLYRQSEIYRRQ
                     GVELSRATLGRWTGAVAELLEPLYDVLRQYVLMPGKVHADDIPVPVQEPGSGKTRTAR
                     LWVYVRDDRNAGSQMPPAVWFAYSPDRKGIHPQNYLAGYSGVLQADAYGGYRALYESG
                     RITEAACMAHARRKIHDVHARAPTYITTEALQRIGELYAIEAEVRGCSAEQRLAARKA
                     RAAPLMQSLYDWIQQQMKTLSRHSDTAKAFAYLLKQWDALNVYCSNGWVEIDNNIAEN
                     ALRGVAVGRKNWMFAGSDSGGEHAAVLYSLIGTCRLNNVEPEKWLRYVIEHIQDWPAN
                     RVRDLLPWKVDLSSQ"
BASE COUNT          668 a          773 c          774 g          588 t
ORIGIN      
        1 tcagataatg cccgatgact ttgtcatgca gctccaccga ttttgagaac gacagcgact
       61 tccgtcccag tgtaaccggc tcatttaaac cgtctggtct gtttcctccg gctctacaaa
      121 aataatgtcc atcattttta atggacacta tcgtatgaaa caccggacct ggatcactga
      181 agctttacgt cttcactttg aagaacattt accccgggtt gtggccgggc gtcgcctggg
      241 tgtaccaaaa tcaacagttt gtagtatgtt cgtgcgcttt cggagagctg gcctttcgtg
      301 gcctttgccc gcaggcatgt cggagcagga acttgatgcc tgcctttacg gacaattttc
      361 cacggtacca gtcgtacgtc ctgaaagcac cgttatatcc gaagcccccg tggtaaaaaa
      421 acgtccccgg cggcccaact tcccttatga gtttaaaatc gccttagtgg agcagtcact
      481 gcagcccgga gcctgtgtgg cgcagatcgc ccgggaaaac ggaatcaacg ataacctgct
      541 cttcaactgg cgccatcaat accggaaagg tggcctgctg ccttccggaa aaaatatgcc
      601 ggcactgctt cccgtgacgt taacgccgga gccggataat aaaatcccgg cccccgcaca
      661 ggaaccagag cagataaata caccgtccga cagtctgtgt tgtgagctgg ttctgccggc
      721 cggaactctc aggcttaaag gtaaactgac gccggcgtta ttacagacac ttatccgcga
      781 aataaaaggg agcagccact gatgatatct ctccctgcag gttcgcgtat ctggctggtt
      841 gcaggtatca ccgatatgcg aaatggcttt aacggcctgg catcaaaagt tcagaacgtc
      901 ctgaaggatg acccgttctc cggacacctg ttcatcttcc gcggacgccg gggtgaccag
      961 ataaaagtgt tgtgggctga cagtgacgga ctgtgcctct tcaccaaacg cctggagcgg
     1021 ggccgcttcg tctggccagt cacccgtgac ggcaaggtgc accttactcc ggctcagtta
     1081 tccatgcttc ttgaaggtat caactggaag cacccgaaac gaacggaacg cgctggaatc
     1141 cgcatataac ccgttgtaaa gtgaggatat ggacacctca cttgctcatg agaacgcccg
     1201 cctgcgggca ctgttgcaga cgcaacagga caccatccgc cagatggctg aatacaaccg
     1261 cctgctctca cagcgggtgg cggcttatgc ttccgaaatc aaccggctga aggcgctggt
     1321 tgcgaaactg caacgtatgc agttcggtaa aagctcagaa aaacttcgtg caaaaaccga
     1381 acggcagata caggaagcac aggagcgaat cagcgcactt caggaagaaa tggcggaaac
     1441 gctgggtgag caatatgacc cggtactgcc atccgccctg cgccagtctt cagcccgtaa
     1501 accgttaccg gcctcacttc cccgtgaaac ccgggttatc cggccggaag aggaatgctg
     1561 tcctgcctgt ggtggtgaac tcagttctct gggatgtgat gtgtcagagc aactggagct
     1621 tatcagcagc gcctttaagg ttatcgaaac acaacgtccg aaacaggcct gttgccggtg
     1681 cgaccatatc gtgcaggcac cagtaccttc aaaacccatt gcacgcagtt atgccggagc
     1741 ggggcttctg gcccatgttg tcaccgggaa atatgcagac catctgccgt tataccgcca
     1801 gtcagaaata taccgtcgtc agggagtgga gctgagccgt gccacactgg ggcgctggac
     1861 aggtgctgtt gctgaactgc tggagccgct gtatgacgtc ctgcgccagt atgtgctgat
     1921 gcccggtaaa gtccatgctg atgatatccc cgtcccggtc caggagccgg gcagcggtaa
     1981 aacccggaca gcccggctgt gggtctacgt ccgtgatgac cgtaacgccg gttcacagat
     2041 gcccccggcg gtctggttcg cgtacagtcc ggaccggaaa ggtatccatc cacaaaatta
     2101 cctggccggt tacagcggtg tgcttcaggc cgatgcttac ggtggttacc gggcgttata
     2161 cgaatccggc agaataacgg aagccgcgtg tatggctcat gcccggagaa aaatccacga
     2221 tgtgcatgca agagcgccca cctacatcac cacggaagcc ctgcagcgta tcggtgaact
     2281 gtatgccatc gaggcagagg tccggggctg ttcagcagaa cagcgtctgg cggcaagaaa
     2341 agccagagcc gcgccactga tgcagtcact gtatgactgg atacagcaac agatgaaaac
     2401 actgtcgcgt cactcagata cggcaaaagc gttcgcatac ctgctgaaac agtgggatgc
     2461 actgaacgtg tactgcagta atggctgggt ggaaatcgac aacaacatcg cagagaacgc
     2521 cttacgggga gtggccgtag gccggaaaaa ctggatgttc gcgggttccg acagcggtgg
     2581 tgaacatgcg gcggtgttgt actcgctgat cggcacatgc cgtctgaaca atgtggagcc
     2641 agaaaagtgg ctgcgttacg tcattgaaca tatccaggac tggccggcaa accgggtacg
     2701 cgatctgttg ccctggaaag ttgatctgag ctctcagtaa atatcaatac ggttctgatg
     2761 agtcgcttac gtcccagtcg tcccagccgt gccaggtgct gcc
//
LOCUS       DAPOAV010000227         2671 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.232, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000227 DAPOAV010000000
VERSION     DAPOAV010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2671
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.232"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(189..407)
                     /locus_tag="RN951_004580"
     CDS             complement(189..407)
                     /locus_tag="RN951_004580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529441.1"
                     /translation="MNNSNNLDYFTLYIIFSIAFMLITLLVILIAKPSTGLGEVLVTI
                     NLLNALVWLAINLVNRLRERLVNHRDQQ"
     gene            complement(539..2062)
                     /locus_tag="RN951_004581"
     CDS             complement(539..2062)
                     /locus_tag="RN951_004581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415686.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDX2529442.1"
                     /translation="MRNTLIPILVAICLFITGVAILNIQLWYSAKAEYLAGARYAANN
                     INHILEEASQATQTAVNIAGKECNLEEQYQLGTEAALKPHLRTIIILKQGIVWCTSLP
                     GNRVLLSRIPVFPDSNLLLAPAIDTVNRLPILLYQNQFADTRILVTISDQHIRGALNV
                     PLKGVRYVLRVADDIIGPTGDVMTLNGHYPYTEKVHSTKYHFTIIFNPPPLFSFYRLI
                     DKGFGILIFILLIACAAAFLLDRYFNKSATPEEILRRAINNGEIVPFYQPVVNGREGT
                     LRGVEVLARWKQPHGGYISPAAFIPLAEKSGLIVPLTQSLMNQVARQMNAIASKLPEG
                     FHIGINFSASHIISPTFVDECLNFRDSFTRRDLNLVLEVTEREPLNVDESLVQRLNIL
                     HENGFVIALDDFGTGYSGLSYLHDLHIDYIKIDHSFVGRVNADPESTRILDCVLDLAR
                     KLSISIVAEGVETKEQLDYLNQNNITFQQGYYFYKPVTYIDLVKIILSKPKVKVVVE"
     gene            complement(2394..2642)
                     /locus_tag="RN951_004582"
     CDS             complement(2394..2642)
                     /locus_tag="RN951_004582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529443.1"
                     /translation="MNNSIPERFIFQCALFKNLEREVFMTHGYVDSHIIDQALRLRLK
                     DETSVILSDLYLQILQYIEMHKTTLTDIIINDRESVLS"
BASE COUNT          823 a          575 c          549 g          724 t
ORIGIN      
        1 aacaaataac tcttcgacat caaaattgtt aatagttgcg atgaggatta tttcggtgat
       61 atataaaaac aaccgtgata acaccagggt tgacaactat ttgcgcaata atgcctttcc
      121 ttcaatgatc caggcgttca ctgccagcaa cccattcagc cgcatactga cagtgagaaa
      181 ctgaaagatt attgctgatc cctgtggttg acgagtcttt ctcttaatcg attaaccaga
      241 ttgatcgcca gccaaacaag ggcattaagc aaatttatcg tcacaagcac ttctcccagc
      301 ccggtactgg gttttgcaat aaggatgacc aggagggtga tcagcataaa tgcaatggaa
      361 aatatgatat agagagtgaa ataatccaga ttattactat tgttcatgct actaatggca
      421 atcctgtcaa aactttcaaa caattatagc aaacaaaata atgaacaata gtaacaagag
      481 gcaacgagct aattagctgt ctataattac accgcactat ggccttactg atcaattttc
      541 actcaaccac aaccttcacc ttcggtttag aaaggataat tttgaccagg tcgatgtatg
      601 taacaggttt atagaaataa taaccctgct gaaatgtgat attattttgg ttcagatagt
      661 caagttgttc tttcgtttcg acaccttcag cgacgatact gatcgaaagt ttacgcgcca
      721 gatccaatac acaatccaga attcgggttg attctgggtc tgcgtttacg cggccaacga
      781 aactgtgatc aattttgata taatcaatat gcaggtcatg aagataagaa agccctgagt
      841 agccagtacc gaaatcatcc agtgcgatga caaaaccatt ttcatgcagt atgttcaacc
      901 gctgaaccag actttcatca acattcaatg gctcacgctc ggtgacttcc agaacaaggt
      961 ttaaatcgcg gcgggtaaaa ctgtcacgga aatttaaaca ctcgtcgaca aacgtcggcg
     1021 aaataatatg cgaagcgcta aaattaattc caatatgaaa accttccggc aatttactcg
     1081 cgatagcgtt catctgtctg gcaacctgat tcatcaggct ttgcgtaagc ggaacgatta
     1141 atccggattt ttcagcaagt ggaataaatg ccgcgggtga tatatatcca ccgtgaggtt
     1201 gtttccagcg ggctaacacc tcaactcccc gcaatgtccc ttcccgacca tttaccacag
     1261 gttggtaaaa agggacgatc tccccattat ttattgcccg tcgcaggatc tcttcaggcg
     1321 ttgcgctttt attgaaatat ctatcaagca ggaaggcagc ggcgcaggcg attaacagaa
     1381 taaatattaa aatcccaaag cctttatcga taagtctgta gaagctaaag agtggcggcg
     1441 ggttaaagat aatagtgaaa tgatattttg tggagtgaac cttctcggta tagggataat
     1501 gtccattaag cgtcatcaca tcacccgttg gtccaataat gtcatccgcc acgcgtaata
     1561 cataccttac ccctttcaag ggtacattaa gtgccccacg aatatgctga tcgcttatcg
     1621 taaccaaaat gcgcgtatct gcaaattggt tctgatagag caggataggt aatctattaa
     1681 cggtgtcgat tgctggagcc aacagtaaat tactgtccgg gaaaacagga atacgagaca
     1741 acaggacccg attcccaggc agggatgtac accagactat tccctgtttg agaatgatga
     1801 ttgtgcgcag gtgaggtttc agagctgctt cagtgccaag ctgatattgc tcctcgaggt
     1861 tgcattcctt cccggcaatg ttaaccgctg tttgagtcgc ttgtgacgct tcttcaagta
     1921 tatgattgat attgttggcg gcatatctcg ctcccgccag gtactctgct tttgcggaat
     1981 accagagctg gatgttcaaa atagcgacac cggtaataaa caagcatatc gcaacgagga
     2041 tgggtatgag tgtattgcgc atttgcttgt cccggccaaa gggtttaata catgaaaatg
     2101 ccattcattc gctcgcgctg gcatctacag agagcatggt agagagcata agaaatatcc
     2161 acgccgaaga taaaattttc tccatcttga tctaacccat taattattga gcataatgta
     2221 ggcagtacaa aataagttag gcgggatatc aggcgtcaag aatggagagc gagaactctc
     2281 cattcttgac acctgatatt gcggacataa taagaaagca taacgcctga aatgctcact
     2341 ttgcatcagc atggtgatac agctgatgtt tattctaaaa ccttactcaa gttctaagag
     2401 agcacggatt ccctgtcatt aataatgata tccgttagtg tagtcttatg catttcaatg
     2461 tactgcaata tttgcagata gagatcagaa agaatcacac tggtttcatc ttttaaacgc
     2521 aagcgtaaag cctgatcaat aatatgacta tcaacatacc catgcgtcat gaacacctcc
     2581 ctctcgagat ttttaaacaa agcacattga aaaataaatc tctctgggat tgaattattc
     2641 atgtcagcct cgtagaaata ttaacccaat a
//
LOCUS       DAPOAV010000228         2618 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.233, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000228 DAPOAV010000000
VERSION     DAPOAV010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2618
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.233"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..609
                     /locus_tag="RN951_004583"
     CDS             <1..609
                     /locus_tag="RN951_004583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001463032.1"
                     /note="cleaves origin of transfer and unwinds; oriT
                     relaxase; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative transfer relaxase/helicase TraI"
                     /protein_id="HDX2529444.1"
                     /translation="GLAGGDSPARFIAPGRKYPQPYVALPAFDRNGRSAGIWLNPLTT
                     DDGNGLRGFSGEGRPWNPGAITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQAEEA
                     IRRETERRADEIVRKMAENKPDLPDGKTELAVRDIAGQERDRTATSERETALPESVLR
                     ESQREREAVREVARENLLQRLLQQMERDMVRDLQKEKTLGGD"
     gene            629..1375
                     /gene="traX"
                     /locus_tag="RN951_004584"
     CDS             629..1375
                     /gene="traX"
                     /locus_tag="RN951_004584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858383.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer pilus acetylase TraX"
                     /protein_id="HDX2529445.1"
                     /translation="MTTDNTNTIRNDSLAARTDTWLQSFLVWSPGQRDIIKTVALVLM
                     VLDHINLIFQLKQEWMFLVGRGAFPLFALVWGLNLSRHAHIRQPAINRLWGWGIIAQF
                     AYYLAGFPWYEGNILFAFAVVAQVLTWCETRSGWRTAAAILLMALWGPLSGTSYGIAG
                     LLMLAVSHRLYRAEDRAERLALVACLLAVIPALNLATSDAAAVAGLVMTVLTVGLVSC
                     AGKSLPRFWPGDFFPTFYACHLAVLGVLAL"
     gene            1430..1990
                     /locus_tag="RN951_004585"
     CDS             1430..1990
                     /locus_tag="RN951_004585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fertility inhibition protein FinO"
                     /protein_id="HDX2529446.1"
                     /translation="MTEQKRPVLTLKRKTEGTAPVRSRKTIINVTTPPKWKVKKQKLA
                     EKAAREAELAAKKAQARQALSIYLNLPSLDEAVNTLKPWWPGLFDGDTPRLLACGIRD
                     VLLEDVAQRNIPLSHKKLRRALKAITRSESYLCAMKAGACRYDTEGYVTEHISQEEET
                     YAAERLDKIRRQNRIKAELQAVLDEK"
     gene            2124..2336
                     /locus_tag="RN951_004586"
     CDS             2124..2336
                     /locus_tag="RN951_004586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529447.1"
                     /translation="MNGFRNSSRNGQVWCWQRAGSRAVILEVSGRWMEAAEGWRRAAC
                     VAPRTDWQQFARKRAEHCHRRCRGRV"
BASE COUNT          631 a          618 c          822 g          547 t
ORIGIN      
        1 gggctggccg ggggagacag tcctgcacgg tttattgctc cgggacgtaa atatccgcaa
       61 ccgtatgtgg cactgccggc ttttgaccgt aacggcaggt ccgccggtat ctggctgaac
      121 ccactgacca cggatgacgg aaacgggctg cggggattca gcggtgaagg ccgtccgtgg
      181 aatcccggtg ccatcaccgg tggccgcgtg tggggggata ttccggataa cagcgtccag
      241 ccgggagccg gaaatggtga accggtcacg gcagaggtac tggcacagcg gcaggctgaa
      301 gaggccatcc gccgtgaaac ggaacgccgc gcagatgaaa ttgtcaggaa aatggcagag
      361 aacaaacctg acttgccgga cggcaaaaca gagctggctg tcagggatat tgccgggcag
      421 gaacgtgacc ggactgccac ttctgaacgg gaaaccgcac tgccggagag tgtgctgcgt
      481 gaatcacaac gggaacggga agcggtccgg gaggttgccc gggaaaatct gctgcagagg
      541 cttctgcagc agatggagcg ggatatggtt cgtgacctgc agaaagagaa aaccctgggc
      601 ggagactgat acaggaagac aaacactgat gacaacggat aacacgaaca cgatacgtaa
      661 cgattcactg gctgcacgga ccgatacctg gttgcagtca tttctggtct ggtcacccgg
      721 acagcgggat atcatcaaaa cggtggcact ggtgctgatg gtactggacc acatcaatct
      781 gatattccag ctgaagcagg aatggatgtt tctggtcggg cgtggggcct ttccgctttt
      841 tgccctggtg tgggggctga atctgtcccg tcatgcgcat atccggcaac cggccattaa
      901 ccggctgtgg ggatggggaa ttattgccca gttcgcatat tatctggcag gctttccctg
      961 gtatgagggg aatatcctgt ttgcctttgc agtggtggca caggtgctga cgtggtgtga
     1021 aacgcgcagt gggtggcgta cagcagcggc cattctcctg atggccctgt gggggccttt
     1081 gtccggcacc agttacggca ttgccgggct gctgatgctg gcagtcagcc accggctgta
     1141 ccgggcggaa gacagagcgg aacgtctggc gctggtcgcc tgcctgctgg ctgttattcc
     1201 ggcgcttaac cttgccacca gtgatgcagc ggcggtggct ggtcttgtga tgacggtgct
     1261 gaccgttggt ctggtgtcgt gtgcaggaaa atcattaccc cgtttctggc ccggagactt
     1321 tttcccgacg ttctatgcct gtcatctggc tgtgctgggc gttctggcgc tgtgacgggt
     1381 gtggtatctt tggccgcaag aggatgattc gtcagaggca gaacacagca tgacagagca
     1441 gaagcgaccg gtactgacac tgaagcggaa gacagaggga acagcgcctg tccgcagccg
     1501 gaaaaccatc atcaatgtca ccacgccacc aaaatggaag gtgaaaaagc agaaactggc
     1561 cgagaaagcg gcccgggaag cagagctggc ggcaaaaaaa gcgcaggcca gacaggcgct
     1621 gtccatttat ctgaacctgc cctcactgga tgaggccgtg aataccctga agccctggtg
     1681 gccgggatta tttgacggtg acacgccccg gcttctggcc tgcggtatcc gggacgtgtt
     1741 actggaagac gtggcgcagc ggaatatccc gctctcgcat aaaaaactgc gcagggcgct
     1801 gaaggccatc acccgttcag aaagctatct gtgtgccatg aaagccggtg cctgccggta
     1861 tgacacggaa gggtatgtga cggagcatat ttctcaggag gaggaaacgt atgcggcaga
     1921 gcgtctggat aaaatccgcc gccagaaccg gataaaggca gaacttcagg ccgtgcttga
     1981 tgagaaataa aaaaaagcct ccctcagaga gaggaggcag ggaaataagg cttaaaagga
     2041 aataacttcc gtacccgaaa ggaagccaat tcagtagatt atttaacacc ataatactga
     2101 cgggttaaag aggagtgata aagatgaatg gattcagaaa cagttcacgg aacggtcagg
     2161 tctggtgctg gcagcgtgcc ggaagccggg ccgttattct ggaggtcagt ggacgctgga
     2221 tggaagcggc agaaggatgg cgacgggctg cctgtgttgc gccccggaca gactggcagc
     2281 agtttgcccg aaaaagggct gaacactgcc accggcgctg ccggggaagg gtgtaacgaa
     2341 aaaagcagcc ttcattactc cagggattca gaaggctgaa taatgcatga gatttgcttt
     2401 ttttaatatc cggtcgggca gtatgaccgg acagttctga gtagcacaga gttttttccg
     2461 tattaagtcg tgattttata ttttgtgatt aatttcacaa aataaggtgt tattcagtgt
     2521 gtgctgcaat attcaggatg cctgaaatac aggtgctatt tatctgatat ggagaataac
     2581 atgaggaaat atattccact ggtattattt atcttttc
//
LOCUS       DAPOAV010000229         2596 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.234, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000229 DAPOAV010000000
VERSION     DAPOAV010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2596
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.234"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..490
                     /locus_tag="RN951_004587"
     CDS             <1..490
                     /locus_tag="RN951_004587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HDX2529448.1"
                     /translation="ITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELN
                     EAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAG
                     WFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIK
                     HW"
     gene            660..1415
                     /locus_tag="RN951_004588"
     CDS             660..1415
                     /locus_tag="RN951_004588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012372818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1405)-N(7))-methyltransferase
                     RmtB1"
                     /protein_id="HDX2529449.1"
                     /translation="MNINDALTSILASKKYRALCPDTVRRILTEEWGRHKSPKQTVEA
                     ARTRLHGICGAYVTPESLKAAAAALSAGDVKKALSLHASTKERLAELDTLYDFIFSAE
                     TPRRVLDIACGLNPLALYERGIASVWGCDIHQGLGDVITPFAREKDWDFTFALQDVLC
                     APPAEAGDLALIFKLLPLLEREQAGSAMALLQSLNTPRMAVSFPTRSLGGRGKGMEAN
                     YAAWFEGGLPAEFEIEDKKTIGTELIYLIKKNG"
     gene            complement(1496..2044)
                     /locus_tag="RN951_004589"
     CDS             complement(1496..2044)
                     /locus_tag="RN951_004589"
                     /inference="COORDINATES: protein motif:HMM:NF013188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDX2529450.1"
                     /translation="MRDTIKVLLLLGASFALVALEKTLGERALFSGLLAVMGMGVTLL
                     KTNAPVAKRISGKFSKLWVAAEIWLFVLVGATVNIRYLFSAGLSGMLLITAALLFRML
                     GVWMSTLGTDLSRKERLFCMIAYLPKATVQAAIGAIPLAMGLGSGETILAVAVLAIIL
                     TAPLGALGIELSYKRLLQKQQS"
     gene            2065..2457
                     /locus_tag="RN951_004590"
     CDS             2065..2457
                     /locus_tag="RN951_004590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529451.1"
                     /translation="MPAGKVLCTDLPWQGINEDQNLGIAITRRALEAPLRAIVANAGE
                     EPSVIVANVKAGEGSYGYNAATGEFGDMIAMGILDPTKVTRSALQHAASVAGLAITTE
                     VVVAEVPKKEEPAMPGAGGMGGMGGMDF"
BASE COUNT          614 a          745 c          709 g          528 t
ORIGIN      
        1 cataaccatg agtgataaca ctgctgccaa cttacttctg acaacgatcg gaggaccgaa
       61 ggagctaacc gcttttttgc acaacatggg ggatcatgta actcgccttg atcgttggga
      121 accggagctg aatgaagcca taccaaacga cgagcgtgac accacgatgc ctgcagcaat
      181 ggcaacaacg ttgcgcaaac tattaactgg cgaactactt actctagctt cccggcaaca
      241 attaatagac tggatggagg cggataaagt tgcaggacca cttctgcgct cggcccttcc
      301 ggctggctgg tttattgctg ataaatctgg agccggtgag cgtgggtctc gcggtatcat
      361 tgcagcactg gggccagatg gtaagccctc ccgtatcgta gttatctaca cgacggggag
      421 tcaggcaact atggatgaac gaaatagaca gatcgctgag ataggtgcct cactgattaa
      481 gcattggtaa ctgtcagacc aagtttactc atatatactt tagattgatt taaaacttca
      541 tttttaattt aaaaggatct aggtgaagat cctttttgat aatctcatga ccaaaatccc
      601 ttaacgtgag ttttcgttcc actgagcgtc agaccccgaa aacgatttag gagacaccga
      661 tgaacatcaa cgatgccctc acctccatcc tggcctcaaa aaaataccgc gccctttgcc
      721 cggataccgt gcggcgcatc ctgactgagg aatgggggcg gcataaatcc cccaaacaga
      781 ccgtagaggc tgcacgcacc cggctgcatg gaatttgcgg ggcatatgtc accccggaat
      841 cgctcaaggc tgctgccgcc gcgctttctg cgggcgatgt aaaaaaggca ttgtcgctgc
      901 atgcctccac caaggagcga ctggccgagc tggataccct gtacgatttt atcttttcag
      961 ccgaaactcc ccgccgcgtg ctggatatcg cctgcggtct taaccccttg gcgctatacg
     1021 agcgcggcat tgcatccgtg tggggctgtg atatccacca gggattgggg gatgtcatca
     1081 ccccctttgc tagggaaaaa gattgggatt ttacctttgc cctgcaggat gtgctgtgtg
     1141 cgccgcccgc cgaagccggc gacctggcgc tgatttttaa gcttttgccc ctgctggagc
     1201 gggagcaggc cggttctgcc atggcacttt tacaatccct caataccccg cgcatggctg
     1261 tcagctttcc cacgcgtagt ttaggcgggc gtggaaaagg catggaggcg aactacgccg
     1321 catggttcga gggcggcttg cccgccgagt ttgagattga ggataaaaag accatcggaa
     1381 cagaacttat atacttgata aaaaagaatg gataagccaa tcagaaggca aatcatctaa
     1441 aaaagaggaa cgaaaaatat ttttcgttcc tcttttgttc tatcgaacaa gcacactacg
     1501 actgctgttt ttgaagcagc cttttatagc tcagctcgat gcccaacgcc cccagcggcg
     1561 ctgtaagtat aatggcaaga accgccaccg caagtatggt ttccccactg ccaagcccca
     1621 tcgccagcgg aatagcgccg attgcagcct gcaccgttgc cttgggcaga taggcaatca
     1681 tgcagaacag gcgctccttc cgggataggt ctgtacccag cgtactcatc cacacgccca
     1741 gcatgcgaaa cagcagcgca gctgtgatca gcagcatgcc gcttagcccg gcggagaaaa
     1801 ggtaacggat gttgaccgtt gcacccacca gcacaaacag ccagatttct gccgccaccc
     1861 aaagctttga aaatttgccg gatatacgct ttgcaaccgg ggcgttggtt tttaaaaggg
     1921 tgacgcccat ccccatcacc gccagcaatc cggaaaatag cgccctttcg cccagggttt
     1981 tctccaacgc aaccagcgca aaggatgcgc ccagcagcag gagcaccttg atcgtatcac
     2041 gcatatgtac ccgcttaaaa agggctgccg gccggcaagg tgctgtgcac ggatctgccc
     2101 tggcagggca tcaacgaaga ccagaacctg ggcatcgcca tcacccgccg tgcgctggaa
     2161 gccccgctgc gcgccatcgt ggccaacgcc ggtgaagaac cgagcgtgat cgtggccaac
     2221 gtcaaggccg gcgaaggcag ctacggctac aacgccgcca ccggcgagtt cggcgacatg
     2281 atcgccatgg gcatcctgga cccgaccaag gtgacccgct cggccctgca gcacgccgct
     2341 tccgtcgccg gccttgcgat cacgaccgaa gtggtcgtgg ccgaagtgcc gaagaaggaa
     2401 gagccggcca tgccgggtgc tggcggtatg ggcggcatgg gcggcatgga tttctgatcc
     2461 ggttggcccg gtcgtcaggg aaccggaccg cgccagcgcg gtccgatccc ggcaacgacc
     2521 cgacatcaag gccccaagga cggggccgga gcccggcagc gatgccgggc tttttgttgt
     2581 gcccgcgccg cggcaa
//
LOCUS       DAPOAV010000230         2541 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.235, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000230 DAPOAV010000000
VERSION     DAPOAV010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2541
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.235"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            411..800
                     /locus_tag="RN951_004591"
     CDS             411..800
                     /locus_tag="RN951_004591"
                     /inference="COORDINATES: protein motif:HMM:NF014430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HDX2529452.1"
                     /translation="MPPFRGLLFLPPLQLSAPGSIGFKNRRQLAAWLGLVPRQCFSVG
                     KNTLGSISKRDDVYIRTLLFHGAKTVSNARKGRQVQESWLGRPVSRRNKNVATVALNN
                     KNARVLWVLLTNDKEISPEEVMVAAYM"
     gene            1254..1436
                     /locus_tag="RN951_004592"
     CDS             1254..1436
                     /locus_tag="RN951_004592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein"
                     /protein_id="HDX2529453.1"
                     /translation="MNHPVIGVVTKADLASMEQISLVKSWLREAGAHNVLVTSAVNNN
                     GVTELFALLHTEEGCC"
     gene            complement(1537..1866)
                     /locus_tag="RN951_004593"
     CDS             complement(1537..1866)
                     /locus_tag="RN951_004593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310836.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF496 family protein"
                     /protein_id="HDX2529454.1"
                     /translation="METTKPSFQDVLEFVRLFRRKNKLQREIQDVEKKIRDNQKRVLL
                     LDNLSDYIKPGMSVEAIQGIIASMKGDYEDRVDDYIIKNAELSKERRDISKKLKAMGE
                     MKNGEAK"
     gene            complement(2038..>2541)
                     /locus_tag="RN951_004594"
     CDS             complement(2038..>2541)
                     /locus_tag="RN951_004594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529455.1"
                     /translation="QSAFSPNLLERPRLESHLQKLLTDAVKMRGLIAPASKETRIPKS
                     IYEGIQTINRNLVCMLELQINAYWATRPSHFVLLNAQKLRDTQHMMQQILLSLVHALY
                     EGNPQPVFANTEKLNDAVEELRQLLNNHHDLKVVETPIYGYVWLNMETAHQLELLSNL
                     ICRALRK"
BASE COUNT          704 a          570 c          600 g          667 t
ORIGIN      
        1 tttgtaaagc catatgtgaa aacaaacaag aatgatatgg ctgctgccga ggccatctgt
       61 gaagccgtta cccgacctaa tatgcggttt gtcagcatca agacgcctga gcagtagtca
      121 ttactgtctt ttcatcgtgc ccaaacggga tttgttaaat caaggactgc gcagataaac
      181 cagatcagag aattactggc tgaatttggc atcgttctcc cgcccgacat tgtagcattc
      241 agtcgtcatg tccctgccct gcttgaagac gcggaaaact gtttaacaat gccgttcaga
      301 cagctgtcgt cctatctcta atgaaaatgt gaaacaactg agcgtacaca ttgaaaccat
      361 agaagccgtg agcaacgaac acgtcgggaa cgacgaactg tgcaggaaaa ttgccaccat
      421 ttcggggatt gctattctta ccaccactgc aattgtcagc accgggtagt atcggcttca
      481 aaaaccggcg tcagcttgct gcatggcttg gactggttcc ccgacagtgc ttcagcgtag
      541 gtaaaaacac gctggggtct atcagtaaac gggacgatgt ctatatcaga acgctactgt
      601 tccatggtgc gaagacagtg tcaaacgcca gaaagggcag acaggtccag gaaagttggc
      661 tgggcagacc agtctcgcgg cggaataaaa atgttgccac cgtagcgctg aacaacaaaa
      721 atgccagagt gctctgggta ttgctaacca acgataaaga gatttcacca gaagaagtga
      781 tggtagctgc atatatgtaa atgaaactac ttctgtctgt tgaaaaataa aacaaaccta
      841 ctgattgcta aggataaaca agtattaaag gccagactga taagaccgcg actaagtgaa
      901 cctgtatctg acatggcata gcttcgctaa tgtgtcatca tgattaggac taaatctgtg
      961 aattccttta ggaagcacgg acacaggcca atctgagtcc atatgtatga ttggaatctt
     1021 acacagatga ctttttgaca cggggacttg gcaaacaggg gcgaccatgt atgtcagata
     1081 tgacaatctc acttccgaaa gaagtcaacg ggcacgttat ctgttcaacc agaatccgac
     1141 acattctggc tatacgaaag agcatactta tgcaaatcta tatgcttttc cggcaacaag
     1201 caggaatctc agcgctgagg caggaattag aggtaaaaac gccctaccgg gccatgaatc
     1261 acccggtcat tggagtagta accaaagcag atttagccag catggaacaa atatctttgg
     1321 tgaaaagttg gttacgggaa gctggagcgc acaacgtgtt agtaaccagt gcagttaata
     1381 acaatggagt tacagaactt tttgccttgc tgcatacaga agaaggctgt tgttaatttc
     1441 gattggttct cagatgagaa tgatgacggt gatacacaga taagaatcaa tgagcaatga
     1501 gggttgccgg gcaaccctca ttgaataaaa cgggaattac ttcgcttcgc cgtttttcat
     1561 ttcgcccata gctttcagct ttttggagat atcgcggcgt tctttggaga gctcggcatt
     1621 tttgatgatg taatcgtcaa cgcgatcttc atagtcacct ttcatgctgg cgatgatgcc
     1681 ctggattgct tcaacgctca tccctggctt gatgtaatcg ctcaggttgt ccagcaacag
     1741 gacgcgcttc tggttgtcac ggatcttttt ctcaacgtcc tgaatttcac gttgcagttt
     1801 gttcttacga cggaacagac gaacaaattc cagtacgtcc tggaatgaag gcttggtagt
     1861 ttccattttt atacccctga taatgtgaga gtcggattcg tttaagcaac cgctattcgt
     1921 tagggccaac attactcata gctgccgcag atgacaatgc ttttatccct tttcactatc
     1981 atacccttta tccttgctga atcgaagcag cagcaagatg attctgaagt tcaggaatta
     2041 tttgcgcaag gcccggcaaa tcagattcga tagcaactca agctgatgtg ccgtttccat
     2101 gttcagccac acataaccat agattggtgt ttccacaacc ttcaggtcat ggtggttatt
     2161 cagcaactga cgcagctctt ccacagcatc gttcaatttt tccgtattgg caaaaaccgg
     2221 ctgcggatta ccttcgtaca gcgcatgaac aaggctcagc agtatttgct gcatcatatg
     2281 ctgggtatca cgaagttttt gcgcgttcaa taacacgaaa tggctggggc gcgtggccca
     2341 gtatgcattg atttgcaact ccagcataca aaccagattg cgattaatgg tctggatacc
     2401 ttcatatatc gattttggaa tacgggtttc tttgctggcg ggcgcaatca gcccacgcat
     2461 tttcacggca tcggtcagga gtttttgtag atggctttcc agacgcgggc gttcgagtaa
     2521 gttcggtgag aatgcagatt g
//
LOCUS       DAPOAV010000231         2482 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.238, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000231 DAPOAV010000000
VERSION     DAPOAV010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2482
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.238"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            314..457
                     /locus_tag="RN951_004595"
     CDS             314..457
                     /locus_tag="RN951_004595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YobF family protein"
                     /protein_id="HDX2529456.1"
                     /translation="MCGIFSKEVLSKHVDVEYRFSAEPYIGASCSNVSVLSMLCLRAK
                     KTI"
     gene            470..679
                     /gene="cspE"
                     /locus_tag="RN951_004596"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             470..679
                     /gene="cspE"
                     /locus_tag="RN951_004596"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HDX2529457.1"
                     /translation="MAKIKGQVKWFNESKGFGFITPADGSKDVFVHFSAIQGNGFKTL
                     AEGQNVEFEIQDGQKGPAAVNVTAI"
     gene            845..1654
                     /gene="rlmA"
                     /locus_tag="RN951_004597"
     CDS             845..1654
                     /gene="rlmA"
                     /locus_tag="RN951_004597"
                     /EC_number="2.1.1.187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(745)-N(1))-methyltransferase"
                     /protein_id="HDX2529458.1"
                     /translation="MSFSCPLCHQPLSREKNSYICPQRHQFDMAKEGYVNLLPVQHKR
                     SRDPGDSAEMMQARRAFLDAGHYQPLLDAIVAQLRERLDDKATAVLDIGCGEGYYTHA
                     FADALPEITTFGLDVSKVAIKAAAKRYPQVTFCVASSHRLPFSDTSMDAIIRIYAPCK
                     AEELARVVKPGGWVITATPGPRHLMELKGLIYNEVHLHAPHAEQLEGFTLQQSAELCY
                     PMRLRGDEAVALLQMTPFAWRAKPEVWQTLAAKEVFDCQTDFNIHLWQRSY"
     gene            complement(1651..2217)
                     /gene="mntP"
                     /locus_tag="RN951_004598"
     CDS             complement(1651..2217)
                     /gene="mntP"
                     /locus_tag="RN951_004598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416335.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese efflux pump MntP"
                     /protein_id="HDX2529459.1"
                     /translation="MNITATVLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFG
                     AVETLTPLIGWGMGMLASRFVLEWNHWIAFVLLIFLGGRMIIEGFRGADDEDEEPRRR
                     HGFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMVGRFIGS
                     IIGKKAEILGGLVLIGIGVQILWTHFHG"
BASE COUNT          659 a          590 c          602 g          631 t
ORIGIN      
        1 gatataactt tttattcatt gcatagcaaa aaatgtgata ttgcacgcac tatgtaataa
       61 cttctcccac tggcctggaa caactgaact tattgaacta tgttagaaaa tacgccagtt
      121 taagtatctg cctgaactgg caaggttaag cacaatgata tatcggcgcg tattccgttg
      181 cataagtgtg caaaaaaagt ggaagacgta tcgagatttg tgcgtctgat cgagacatgt
      241 ttaaaaatgg cttgccataa ttaacgttgt atgtgataac agatttcggg ttaaacgagg
      301 tacagttctg tttatgtgtg gcattttcag taaagaagtc ctgagtaaac acgttgacgt
      361 tgaataccgc ttctctgccg agccttatat tggtgcctca tgcagtaatg tgtcagtttt
      421 atctatgtta tgcctgcggg cgaagaaaac aatctaagga atttttcaaa tggcaaagat
      481 taaaggtcag gttaagtggt tcaacgagtc taaaggtttt ggcttcatta ctccggctga
      541 tggcagcaaa gatgtgttcg tacacttctc cgctatccag ggtaatggct tcaaaactct
      601 ggctgaaggt cagaacgttg agttcgaaat tcaggacggc cagaaaggtc cggcagctgt
      661 taacgtaaca gctatctgat cgaatccact gatctgaagt gtgaatacgc ttcaatctcg
      721 ctataaagcc tcgtcgaatg cgaggctttt tactatgctt tatcttcgct cctggcgttc
      781 ggatatttgc ccgccgcgtg attcgcgtta cacttgcggc ctttagtatc ctgccggagt
      841 tgtcatgtct ttttcctgtc cactttgcca tcagcctctt tcgcgtgaaa aaaacagcta
      901 tatctgtccc cagcgacatc agtttgatat ggcgaaagaa gggtatgtca atctgctgcc
      961 cgttcagcat aaacggtctc gtgatccggg cgacagcgcg gaaatgatgc aagcacgccg
     1021 cgcattctta gatgccggac attatcagcc gctgcttgat gcaattgtcg cccaactgag
     1081 ggaacggctt gatgataagg ccacggcggt gctggatatt ggctgtggtg aagggtatta
     1141 cacacacgca tttgccgatg cgttgcccga aatcaccacg tttggtctgg atgtttcgaa
     1201 ggtagcgata aaagcggcgg cgaaacgcta tccgcaggtc actttttgtg tcgcttccag
     1261 ccaccgtttg ccgttttccg ataccagtat ggacgccata atacgtattt acgcgccgtg
     1321 taaagcagaa gaattagcac gagtagtgaa gcccggcggc tgggtcatta ctgccacgcc
     1381 gggaccgcga catttgatgg agctgaaggg gctgatttac aatgaagtac atcttcatgc
     1441 acctcatgca gaacaactgg aaggttttac attacagcag agtgcggagt tgtgttatcc
     1501 gatgcgtctt cgcggtgatg aagccgtcgc attattgcag atgacgccgt ttgcctggcg
     1561 tgcgaagcca gaagtctggc aaacactggc agcaaaagaa gtgttcgact gccagacgga
     1621 ctttaatatt cacctctggc agcgttctta ttaaccgtgg aagtgcgtcc agaggatctg
     1681 gacgccgatg ccgatcagca ccagcccgcc gagaatttcc gcttttttcc caataattga
     1741 gccgataaag cgaccaacca tcatccctaa tgttgacata atcaaggttg cacaaccaat
     1801 ggccaatgcg gtcgcgataa tgttgacctg caggaaagca agaccaacac ccacagccat
     1861 ggcatccagg ctggtggcaa tcgcggtggt taccagtagc cagaaaccgt gtcgacggcg
     1921 cggctcttca tcttcatcat ctgcgccacg aaaaccctca ataatcattc gcccgccgag
     1981 gaatatcagc agcacaaacg caatccagtg gttccattca aggacaaacc ggctggctaa
     2041 catgcccatt ccccagccga tcagcggcgt cagggtttcg acggcaccaa aaataaggcc
     2101 ggttcgcaat gcttcagaaa atttcggttt atggagggtg gcacctttac cgattgatgc
     2161 agcaaatgca tccatcgaca taccaaacgc aagaagaaca gtagcagtga tattcatgac
     2221 aatgtcctga ccggggtatc cataaaacac atcatcgccc ccagcaaaca tgcatacatg
     2281 aacaacaagc cgtgatggtt ttcgcgttca tgcaggcata gcgattgatg tgcatatggt
     2341 ctcgcctgac tgaaagtatt cagtccgtac gtgccacgtt ttgcaacgag tatgttgaca
     2401 cgtacatttc cggaatctgg aaatcggcta ctccccaaat gagggcgcaa ccttaacata
     2461 ttttgagaat ataaaacaac tg
//
LOCUS       DAPOAV010000232         2424 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.239, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000232 DAPOAV010000000
VERSION     DAPOAV010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2424
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.239"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            62..2341
                     /gene="ydeP"
                     /locus_tag="RN951_004599"
     CDS             62..2341
                     /gene="ydeP"
                     /locus_tag="RN951_004599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance putative oxidoreductase YdeP"
                     /protein_id="HDX2529460.1"
                     /translation="MKKKIESYQGAAGGWGAVKSVANAVRKQMDIRQDVIAMFDMNKP
                     EGFDCPGCAWPDPKHSASFDICENGAKAIAWEVTDKQVNASFFAENTVQSLLTWGDHE
                     LEAAGRLTQPLKYDAVSDCYKPLSWQQAFDEIGARLQSYSDPNQVEFYTSGRTSNEAA
                     FLYQLFAREYGSNNFPDCSNMCHEPTSVGLAASIGVGKGTVLLEDFEKCDLVICIGHN
                     PGTNHPRMLTSLRALVKRGAKMIAINPLQERGLERFTAPQNPFEMLTNSETQLASAYY
                     NVRIGGDMALLKGMMRLLIERDDAASAAGRPSLLDDEFIQTHTVGFDELRRDVLNSEW
                     KDIERISGLSQTQIAELADAYAAAERTIICYGMGITQHEHGTQNVQQLVNLLLMKGNI
                     GKPGAGICPLRGHSNVQGDRTVGITEKPSAEFLARLGERYGFTPPHAPGHAAIASMQA
                     ICTGQARALICMGGNFALAMPDREASAVPLTQLDLAVHVATKLNRSHLLTARHSYILP
                     VLGRSEIDMQKNGAQAVTVEDSMSMIHASRGVLKPAGVMLKSECAVVAGIAQAALPQS
                     VVAWEYLVEDYDRIRNDIEAVLPEFADYNQRIRHPGGFHLINAAAERRWMTPSGKANF
                     ITSKGLLEDPSSAFNSKLVMATVRSHDQYNTTIYGMDDRYRGVFGQRDVVFMSAKQAK
                     ICRVKNGERVNLIALTPDGKRSSRRMDRLKVVIYPMADRSLVTYFPESNHMLTLDNHD
                     PLSGIPGYKSIPVELEPSN"
BASE COUNT          624 a          577 c          626 g          597 t
ORIGIN      
        1 atgtactgtg catcatcgct attacaaatc ctaataattc atttccacac aggataagta
       61 gatgaagaaa aaaattgaat cctaccaggg tgctgcaggt ggttggggtg ctgttaaatc
      121 cgtagcgaat gcagtacgta agcagatgga tatacgccag gatgttattg ccatgtttga
      181 catgaataag ccagagggct ttgactgtcc gggttgtgca tggccagatc ctaagcacag
      241 tgcgtcattc gacatttgtg aaaacggcgc aaaagcaatc gcctgggaag tcacggataa
      301 gcaggtaaac gcctctttct ttgctgagaa tacggttcaa tcattactta cctggggaga
      361 ccacgagctt gaggctgcgg ggcgactcac tcagcctttg aaatatgatg ccgtcagcga
      421 ctgttacaag ccattaagct ggcaacaagc tttcgacgaa attggcgcac gccttcaaag
      481 ctatagtgat cccaatcagg ttgaattcta tacttcgggc cgcacttcca atgaagctgc
      541 ctttctttat cagctttttg cccgtgaata cgggagcaat aactttcccg actgctccaa
      601 catgtgccat gaaccgacaa gcgtgggttt ggcagcgagt atcggtgtag gtaaagggac
      661 cgtgttgctg gaagactttg agaagtgcga tttagtcatt tgcattgggc ataaccctgg
      721 tacaaaccac cctcgcatgc tgacttcgtt gcgcgcttta gtgaaacggg gagcgaaaat
      781 gatcgccatc aatcctctac aggaacgtgg cctggagcga tttaccgcac cgcaaaaccc
      841 gtttgaaatg ctgacgaact ctgagactca gttggccagt gcctactata acgtgcgcat
      901 tggtggcgat atggcgttgc tcaaggggat gatgcgcctg ttaattgagc gcgatgatgc
      961 tgcaagcgcc gcaggtcggc cttcattgct tgatgacgag tttattcaaa cgcataccgt
     1021 cggctttgac gagctacgcc gtgacgttct caattccgag tggaaagata tcgaacgtat
     1081 ttctggacta agtcagacac aaatcgccga actggctgac gcatatgccg ctgccgaacg
     1141 caccattatc tgttacggaa tggggatcac tcagcacgaa catggtaccc agaacgtaca
     1201 gcaactggtc aatctgctgt tgatgaaagg taacattggc aagcctggtg cgggtatctg
     1261 cccactacgt ggacactcta atgtacaggg cgaccgaacc gtcggtatca ccgagaaacc
     1321 gtctgcagag tttctggctc gtctgggtga gcgctatggc ttcaccccac ctcatgcacc
     1381 tggacatgct gcaattgcca gcatgcaagc aatatgtacg gggcaggctc gagcattgat
     1441 ctgcatgggg ggcaattttg cgctggcaat gccagatcgg gaagcgagcg ctgtaccgtt
     1501 aacgcaatta gatttggcgg tacacgtagc cactaagctt aaccgctctc atctgttgac
     1561 cgcacggcat agctatattc tgccggtcct gggacgtagc gagattgaca tgcaaaaaaa
     1621 cggtgcgcag gcggtaaccg ttgaggattc aatgtcgatg attcatgcct cgcgtggcgt
     1681 gttaaaaccc gccggtgtaa tgctgaaatc agagtgtgca gtggtcgcgg gaatcgcgca
     1741 ggcagcacta ccccagagcg tggtagcctg ggagtatctg gtggaagatt atgatcgcat
     1801 tcgcaatgac attgaagctg tgctgccaga gttcgccgac tataaccagc gcatccgtca
     1861 tcccggtggt tttcacctga taaatgcagc tgctgaaagg cgctggatga cgccgtcagg
     1921 taaggctaat ttcattacca gcaaagggct gttagaagat ccctcttcag cgtttaacag
     1981 taagctggtc atggcgacag tacgcagcca cgatcagtac aacacgacga tttatggtat
     2041 ggatgatcgc tatcgagggg tattcggtca acgagatgtg gtctttatga gtgctaaaca
     2101 agctaaaatt tgccgtgtaa aaaacggcga aagagttaat cttattgcgc ttacgccaga
     2161 cggtaagcgc agctcacgcc gcatggatag attaaaagtg gtcatttacc ctatggctga
     2221 ccgctcactg gtgacctatt ttccagaatc gaatcacatg ctaacacttg ataaccacga
     2281 tccattaagt ggcattcctg gctataaaag tattccggtt gaattagaac catcaaatta
     2341 atgcctcttc tcatttcttc tgctgtcatc cgcacagcag aagaattcct cattgactat
     2401 tatttcgcaa tttgctcaca tgga
//
LOCUS       DAPOAV010000233         2388 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.240, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000233 DAPOAV010000000
VERSION     DAPOAV010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2388
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.240"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..111)
                     /locus_tag="RN951_004600"
     CDS             complement(<1..111)
                     /locus_tag="RN951_004600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraL"
                     /protein_id="HDX2529461.1"
                     /translation="MSGDENKLKKYRFPETLTNQSRWFGLPLDELIPAAIC"
     gene            complement(126..491)
                     /gene="traA"
                     /locus_tag="RN951_004601"
     CDS             complement(126..491)
                     /gene="traA"
                     /locus_tag="RN951_004601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system pilin TraA"
                     /protein_id="HDX2529462.1"
                     /translation="MNAVLSVQGASAPVKKKSFFSKFTRLNMLRLARAVIPAAVLMMF
                     FPQLAMAAGSSGQDLMASGNTTVKATFGKDSSVVKWVVLAEVLVGAVMYMMTKNVKFL
                     AGFAIISVFIAVGMAVVGL"
     gene            complement(524..919)
                     /gene="traY"
                     /locus_tag="RN951_004602"
     CDS             complement(524..919)
                     /gene="traY"
                     /locus_tag="RN951_004602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001366159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer relaxosome protein TraY"
                     /protein_id="HDX2529463.1"
                     /translation="MKRFGTRSATGKMVKLKLPVDVESLLIEASNRSGRSRSFEAVIR
                     LKDHLHRYPKFNRAGNIYGKSLVKYLTMRLDDETNQLLIAAKNRSGWCKTDEAADRVI
                     DHLIKFPDFYNSEIFREADKEEDITFNTL"
     gene            complement(1018..1707)
                     /gene="traJ"
                     /locus_tag="RN951_004603"
     CDS             complement(1018..1707)
                     /gene="traJ"
                     /locus_tag="RN951_004603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003979562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer transcriptional regulator
                     TraJ"
                     /protein_id="HDX2529464.1"
                     /translation="MYPMDRIQQKHARQIDLLENLTAVIQDYPNPACIRDETGKFIFC
                     NTLFHESFLTQDQSAEKWLLSQRDFCELISVTEMEAYRNEHTHLNLVEDVFIQNRFWT
                     ISVQSFLNGHRNIILWQFYDAAHVRHKDSYNQKTIVSDDIRNIIRRMSDDSSVSSYVN
                     DVFYLYSTGISHNAIARILNISISTSKKHASLICDYFSVSNKDELIILLYNKKFIYYL
                     YEKAMCIINTR"
     gene            complement(1894..2277)
                     /locus_tag="RN951_004604"
     CDS             complement(1894..2277)
                     /locus_tag="RN951_004604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxosome protein TraM"
                     /protein_id="HDX2529465.1"
                     /translation="MAKVNLYISNDAYEKINAIIEKRRQEGAREKDVSFSATASMLLE
                     LGLRVHEAQMERKESAFNQTEFNKLLLECVVKTQSSVAKILGIESLSPHVSGNPKFEY
                     ANMVEDIREKVSSEMERFFPKNDDE"
BASE COUNT          726 a          521 c          409 g          732 t
ORIGIN      
        1 acagattgct gcggggatca gttcatccag tggcaggcca aaccagcggc tctggttggt
       61 cagtgtttcc gggaaacgat atttcttaag tttattctcg tctcccgaca tcgttttatt
      121 tcctgtcaga ggccaacgac ggccataccc acagcaataa atacagagat gatggcaaaa
      181 ccggccagga acttgacgtt tttggtcatc atgtacatga cagcaccgac cagaacttca
      241 gccagaacaa cccatttaac aacactggag tccttaccga aggtcgcctt aaccgtggtg
      301 ttaccgcttg ccatcaggtc ctgaccactg ctgccggcgg ccatcgccag ctgcgggaag
      361 aacatcatca gaacagcagc cgggatcact gcgcgagcca ggcgaagcat attcagacga
      421 gtgaatttag aaaaaaacga cttctttttg acgggcgcag aagcaccctg aacacttaaa
      481 acagcattca taagttacct caatttcgga taaatgaata aaactagagt gtattaaatg
      541 ttatatcttc ctctttatct gcctccctga atatctccga gttataaaaa tcaggaaact
      601 tgatcaaatg atcaataact ctgtctgcag cctcatctgt tttacaccat ccactacgat
      661 ttttggctgc aataagtagc tggttagttt catcatccag acgcattgtc agatacttaa
      721 ccagcgactt accatagata ttccctgccc tgttaaactt tggatagcgg tgaagatgat
      781 ctttaagtct tattactgcc tcaaacgatc gacttcttcc gcttctgtta cttgcctcaa
      841 ttaatagact ttccacatct acaggtaatt ttagttttac catcttacct gttgcagaac
      901 gtgtaccaaa tcttttcaat aacacctccc gctgtttatc ttctggttac cacttatgtt
      961 tacagaataa tcagaaaagg taaatagacg gaaagtctat attttatcaa caccttatta
     1021 acgcgtattt atgatacaca tagccttctc gtataaataa taaataaact ttttattgta
     1081 gagtaagata attaactcat ctttattaga aacagagaag tagtcgcata tcagagatgc
     1141 gtgtttcttt gatgtggaga tggatatatt taatattctt gctatagcat tatgactgat
     1201 tccggtgcta tataagtaaa agacatcatt tacatatgat gatacagaag aatcatcact
     1261 cattcttctg attatatttc tgatatcatc actgacaatc gttttttgat tataactgtc
     1321 tttatgacga acatgagcag catcataaaa ttgccacaga ataatatttc tgtgtccatt
     1381 aagaaatgac tggacagata ttgtccagaa tctgttctga ataaaaacat cctctacaag
     1441 attaagatgc gtatgctcat tcctgtatgc ttccatctct gtgacagaga tcaattcaca
     1501 aaaatctctc tgcgacagaa gccatttttc agcactttga tcttgtgtaa gaaatgactc
     1561 atgaaacagc gtattgcaaa aaataaattt tccagtttcg tccctgatac aggctggatt
     1621 tggataatcc tgaataactg ccgtcagatt ttccagcaga tctatttgac gagcatgttt
     1681 ttgttgaata cgatccatcg gatacatagg aacctcctca caaaggattc tatggacagt
     1741 cgatgcaggg aggagagaac tccctgcatc ggcgattttc aaattcaaat tttaacgtgg
     1801 cattaaccac gtaattaata tactaattat ctttcgtact gtcacctttt taaatcataa
     1861 aaactctgat atttgaacga agtcaaattt cttttattca tcatcatttt ttggaaaaaa
     1921 tcgttccatc tcagatgata ccttctccct gatatcttca accatattgg catattcaaa
     1981 ctttggattt ccggagacat gaggactgag agactcaata cccaaaattt tcgctactga
     2041 tgattgtgtt tttacaacgc attcaagaag caatttatta aactcagtct gattaaatgc
     2101 agactcttta cgctccatct gagcctcatg tacacgaagc cccagttcaa gaagcattga
     2161 agctgttgct gaaaaactga catctttttc ccttgcccct tcctgtcgac gcttctcaat
     2221 aatcgcattt attttttcat aggcatcatt gctgatatac aggttcacct tagccattag
     2281 agattacctt ttttgaacat aaaataaagt taatttcgaa acactaaaat tcataatgca
     2341 aacagggacg caccgctagc agcgccccta gcggtatcct ataaaaaa
//
LOCUS       DAPOAV010000234         2365 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.241, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000234 DAPOAV010000000
VERSION     DAPOAV010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2365
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.241"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            1..792
                     /gene="nirC"
                     /locus_tag="RN951_004605"
     CDS             1..792
                     /gene="nirC"
                     /locus_tag="RN951_004605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026212.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite transporter NirC"
                     /protein_id="HDX2529466.1"
                     /translation="MNKCAANAARIARLSANNPLGFWVSSAMAGAYVGLGIILIFTLG
                     NLLDPSVRPLVMGATFGIALTLVIIAGSELFTGHTMFLTFGVKAGSISHGQMWAILPQ
                     TWLGNLVGSVFVAMLYSWGGGSLLPVDTSIVHSVALAKTTAPAMVLFFKGALCNWLVC
                     LAIWMALRTEGAAKFIAIWWCLLAFIASGYEHSIANMTLFALSWFGNHSEAYTLAGIG
                     HNLLWVTLGNTLSGAVFMGLGYWYATPKANRPVADKFNQTETAAG"
     gene            811..2184
                     /gene="cobA"
                     /locus_tag="RN951_004606"
     CDS             811..2184
                     /gene="cobA"
                     /locus_tag="RN951_004606"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HDX2529467.1"
                     /translation="MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALA
                     FIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNV
                     VDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQ
                     LRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEV
                     VLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHC
                     VPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAAS
                     GCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQ
                     KLIEHGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDK
                     LNWFSNH"
BASE COUNT          523 a          599 c          660 g          583 t
ORIGIN      
        1 attaataagt gtgcggctaa cgctgcgcgc attgcacgcc tgtcggcaaa taacccgctc
       61 ggcttttggg tcagctccgc catggcgggc gcgtatgtgg gtcttgggat catcctgatt
      121 ttcacgctcg gtaatttgct cgatccatcc gtacgccctt tggtgatggg cgcgaccttt
      181 ggtatcgcct taacgctggt gattatcgcc ggttctgaac tgttcaccgg acacaccatg
      241 ttcctcacct ttggggtaaa agcgggcagc atcagccacg ggcaaatgtg ggcaatcctg
      301 ccgcaaacct ggctgggtaa cctggtcggt tccgtcttcg ttgccatgct ctatagctgg
      361 ggcggcggta gcctgctgcc ggtagatacc agcatcgttc actccgtcgc gctggctaaa
      421 accactgcac cggcaatggt actcttcttc aaaggtgcat tgtgtaactg gctggtttgc
      481 ctggcaatct ggatggcgct gcgcactgaa ggggcggcga aatttatcgc tatctggtgg
      541 tgtctgctgg catttatcgc gtccggctac gagcactcta tcgctaacat gacgctgttc
      601 gcgctctcct ggttcggcaa ccacagcgaa gcctacacgc tggcgggtat tggtcataac
      661 ctgctgtggg tgacgctggg taatacttta tcaggtgccg tattcatggg attgggttat
      721 tggtatgcta cgccgaaagc gaatcgtccg gttgcggaca aatttaatca aactgaaacg
      781 gctgccggtt aattactaag gggtttttac gtggatcatt tgcctatatt ttgccaatta
      841 cgcgatcgcg actgtctgat tgtcggcggt ggtgatgtcg cggaacgcaa agcaaggttg
      901 ctgttagacg caggcgctcg cttaacggtg aatgcattag cgtttattcc acagttcacc
      961 gcatgggcag atgcaggcat gttaaccctc gtcgaagggc catttgatga aagccttctc
     1021 gacacctgct ggctggcgat tgcagcgacg gatgatgacg cgcttaacca gcgcgtcagc
     1081 gaagccgctg aagctcgtcg catcttctgt aacgtggtcg atgcgccgaa agccgccagc
     1141 tttattatgc cgtcgattat tgaccgctca ccgctcatgg tagcggtctc ctctggcggc
     1201 acctctccgg ttctggcacg cctgttgcgc gaaaaacttg aatcactgct gccgttacat
     1261 ctgggccagg tagcgaaata cgccgggcaa ttacgcgggc gagtgaaaca acagttcgcc
     1321 acgatgggtg agcgtcgccg tttctgggag aaattgttcg ttaacgaccg cctggcgcag
     1381 tcgctggcaa acaacgatca gaaagccatt actgaaacga ccgaacagtt aatcaacgaa
     1441 ccgctcgacc atcgcggtga agtggtgctg gttggtgcag gtccgggcga tgccgggctg
     1501 ctgacactga aaggactgca acaaattcag caggcagatg tggtggtcta cgaccgtctg
     1561 gtttctgacg atattatgaa tctggtacgc cgcgatgcgg accgtgtttt cgtcggcaaa
     1621 cgcgcgggat accactgcgt accccaggaa gagattaacc agatcctgct gcgggaagcg
     1681 caaaaaggca aacgcgtggt gcggctgaaa ggtggcgatc cgtttatttt tggccgtggt
     1741 ggcgaagagc tggaaacact gtgcaacgcg ggtattccgt tctcggtggt tccgggtatt
     1801 accgcagctt ctggttgctc tgcctattcg ggtattccac tcacgcatcg cgattatgcc
     1861 cagagcgtac gcttaattac cggacactta aaaaccggtg gcgagctgga ctgggaaaac
     1921 ctggcggcag aaaaacagac gctggtgttc tatatggggt tgaatcaggc cgcgactatt
     1981 cagcaaaagc tgattgaaca cggaatgcca ggcgaaatgc cggtggcaat tgtcgaaaac
     2041 ggtacggcag tcacgcagcg cgtgattgac ggtacgctca cacagctggg agaactggcg
     2101 cagcaaatga acagtccatc gctaattatt attggtcggg ttgttggcct gcgcgataaa
     2161 ctgaactggt tctccaacca ttaatttaac ccgggccaga gaattctggc cttcttaatg
     2221 actcttttta tatattcagc aaataaaaca tagcccctta ataaatatta tctgctaatg
     2281 ggttatattc accgttacag cgacttacaa aattaagtca ttcgctcact gacgccaatt
     2341 aaatattcct gtatcgttct taacg
//
LOCUS       DAPOAV010000235         2354 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.242, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000235 DAPOAV010000000
VERSION     DAPOAV010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2354
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.242"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            100..513
                     /gene="hiuH"
                     /locus_tag="RN951_004607"
     CDS             100..513
                     /gene="hiuH"
                     /locus_tag="RN951_004607"
                     /EC_number="3.5.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyisourate hydrolase"
                     /protein_id="HDX2529468.1"
                     /translation="MLKRYLVLSVATAAFSLPSLVYAAQQNILSVHILNQQTGKPAAD
                     VTVTLEKKADNGWLQLNTAKTDKDGRIKALWPEQTATTGDYRVVFKTGDYFKKQNLES
                     FFPEIPVEFHINKVNEHYHVPLLLSQYGYSTYRGS"
     gene            622..1626
                     /gene="msrP"
                     /locus_tag="RN951_004608"
     CDS             622..1626
                     /gene="msrP"
                     /locus_tag="RN951_004608"
                     /EC_number="1.8.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase catalytic
                     subunit MsrP"
                     /protein_id="HDX2529469.1"
                     /translation="MKKNQFLKESDVTAESVFFMKRRQVLKALGISAAALSLPHAAHA
                     DLLSWFKGNDRPPAPAGKPLEFSKPAAWQNNLPLTPADKVSGYNNFYEFGLDKADPAA
                     NAGSLKTDPWTLKISGEVAKPLTLDHDDLTRRFPLEERIYRMRCVEAWSMVVPWIGFP
                     LHKLLALAEPTSNAKYVAFETIYAPEQMPGQQDRFIGGGLKYPYVEGLRLDEAMHPLT
                     LMTVGVYGKALPPQNGAPVRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLAAPDEYG
                     FYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYADQVASLYRGLDLRENF
                     "
     gene            1627..2262
                     /gene="msrQ"
                     /locus_tag="RN951_004609"
     CDS             1627..2262
                     /gene="msrQ"
                     /locus_tag="RN951_004609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase
                     heme-binding subunit MsrQ"
                     /protein_id="HDX2529470.1"
                     /translation="MRLTAKQVTWLKVSLHLAGLLPFLWLVWAINHGGLGADPVKDIQ
                     HFTGRTALKFLLATLLITPLARYAKQPLLIRTRRLLGLWCFAWATLHLTSYALLELGV
                     NNLALLGKELITRPYLTLGIISWVILLALAFTSTQAMQRKLGKHWQQLHNFVYLVAIL
                     APIHYLWSVKIISPQPLIYAGLALLLLALRYKKLRSLFNRLRKQVHNKLSV"
BASE COUNT          598 a          578 c          568 g          610 t
ORIGIN      
        1 aacagcctgg ttcattacaa aattgtaatg ctgctgtaag gttaccctgg ccgctttttc
       61 gctatcctca aaactcattc acatgacaag gatataaaca tgttaaagcg ttatttagta
      121 ctctcggtag caacggcagc attttcatta ccttctttgg tttatgccgc acaacaaaac
      181 attcttagcg tgcacatttt gaaccagcaa accggaaaac ccgctgctga cgtgacagtc
      241 actcttgaaa agaaggcgga taacggctgg ttacaactta ataccgccaa aacagataag
      301 gatggacgaa ttaaggcact gtggcccgag caaactgcga ctactggcga ttaccgtgtc
      361 gtatttaaaa ccggggacta tttcaagaaa caaaatcttg aaagtttctt ccctgagatc
      421 cccgttgaat ttcatattaa taaagtgaac gagcattatc atgtgccttt attacttagc
      481 caatatgggt attcaaccta tcgtggcagt taaagcataa atatgtaaaa gcagatctct
      541 gctactgtta gggaggacac tccctgacag attaacagta aacggctctt gctggctaac
      601 gacaaaaaag tgtgatggct tatgaaaaag aatcaatttt taaaagaatc agatgttacg
      661 gccgagtcgg tattctttat gaagcgtcgg caggtgttaa aagcactggg catcagcgca
      721 gctgcacttt ctttgcctca cgctgcgcat gccgatctgc ttagctggtt taaagggaac
      781 gatcgcccac ccgcccccgc cggaaaaccg ctggagttca gcaagcctgc cgcctggcaa
      841 aataacctgc cactgacgcc agcagataaa gtctccggtt ataacaactt ctatgaattc
      901 gggctggata aagccgatcc cgccgctaat gctggtagcc tgaaaaccga tccatggaca
      961 ctgaaaatca gcggcgaagt ggcaaaacca ttgaccctcg atcacgatga tttaacccgt
     1021 cgcttcccgc tggaagagcg tatttatcgt atgcgctgcg tggaggcatg gtcgatggtg
     1081 gtgccgtgga ttggttttcc gctgcacaaa ttgctggcgc ttgccgaacc caccagcaat
     1141 gcgaagtatg tcgctttcga aacaatttat gcaccggaac aaatgccagg ccagcaggac
     1201 cgctttatcg gcggcgggct gaaatatcct tatgtcgaag gattgcgtct cgacgaagca
     1261 atgcatccgc tcacactgat gaccgtgggt gtttatggca aggcgttacc gccacaaaat
     1321 ggcgcgccgg tacgactgat tgtgccgtgg aaatatggct ttaaagggat taaatcgata
     1381 gtcagtatta agctgacccg cgagcgtccg ccaaccacct ggaatctggc agcgcctgac
     1441 gaatacggtt tttacgccaa cgttaatccg catgttgatc acccgcgctg gtcacaggct
     1501 accgaacgat ttattggttc aggcggcatc ctcgatgttc agcgtcagcc aacgctactg
     1561 tttaatggtt acgccgacca ggtggcatcg ctgtatcgtg gcctggattt gcgggagaat
     1621 ttctgaatgc gtctgacagc aaaacaggtg acatggctga aagttagcct gcatcttgcc
     1681 ggattgttgc cgtttctctg gctggtctgg gcgatcaatc acggtggact gggtgccgat
     1741 ccggtgaaag atattcagca ttttaccggt cgcactgcac tgaaattttt gctggcgacc
     1801 ttgttaatca cacctctggc acgctacgca aaacagccgt tattgatacg cactcgccgc
     1861 ctgttaggct tatggtgctt tgcctgggcg acactgcatt taaccagtta cgcattgctg
     1921 gagctgggcg tgaataatct ggcgttatta ggcaaggagt taattacccg gccttattta
     1981 acgttaggaa ttatcagctg ggttattttg cttgctttag cgtttacttc aacccaggcg
     2041 atgcagcgaa aactcggcaa gcactggcaa cagttgcata atttcgtcta tcttgtcgcg
     2101 atcctggccc caatacatta tctgtggtca gtgaagatta tttcaccgca gccgctcatc
     2161 tacgctgggc tggctttact gcttttagcc ttacggtata agaagttgcg ttcccttttt
     2221 aaccggttac gcaagcaggt tcacaacaaa ttatctgtat aacttcatat tgccgacaaa
     2281 gtacgcgtta tccctgccgg atgcggcgcg agcgccctat ccggcctacg cagatcacat
     2341 caggttatgt ttcg
//
LOCUS       DAPOAV010000236         2353 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.243, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000236 DAPOAV010000000
VERSION     DAPOAV010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2353
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.243"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..711
                     /gene="agaC"
                     /locus_tag="RN951_004610"
     CDS             <1..711
                     /gene="agaC"
                     /locus_tag="RN951_004610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIC"
                     /protein_id="HDX2529471.1"
                     /translation="RPIIVCTLTGAILGDIQTGLITGGLTELAFAGLTPAGGVQPPNP
                     IMAGLMTTVIAWSTGVDAKTAIGLGLPFSLLMQYVILFFYSAFSLFMTKADKCAKEAD
                     TAAFSRLNWTTMLIVASAYAVIAFLCTYLAQGAMQALVKAMPAWLTHGFEVAGGILPA
                     VGFGLLLRVMFKAQYIPYLIAGFLFVCYIQVSNLLPVAVLGAGFAVYEFFNAKSRQQA
                     QPQPVASKNEEEDYSNGI"
     gene            701..1492
                     /gene="agaD"
                     /locus_tag="RN951_004611"
     CDS             701..1492
                     /gene="agaD"
                     /locus_tag="RN951_004611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IID"
                     /protein_id="HDX2529472.1"
                     /translation="MGSEISKKDITRLGFRSSLLQASFNYERMQAGGFTWAMLPILKK
                     IYKDDKPGLSAAMKDNLEFINTHPNLVGFLMGLLISMEEKGENRDTIKGLKVALFGPI
                     AGIGDAIFWFTLLPIMAGICSSFASQGNLLGPILFFAVYLLIFFLRVGWTHVGYSVGV
                     KAIDKVRENSQMIARSATILGITVIGGLIASYVHINVVTSFAIDNTHSVALQQDFFDK
                     VFPNILPMAYTLLMYYFLRVKKAHPVLLIGVTFVLSIVCSAFGIL"
     gene            1493..2248
                     /locus_tag="RN951_004612"
     CDS             1493..2248
                     /locus_tag="RN951_004612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosamine-6-phosphate isomerase"
                     /protein_id="HDX2529473.1"
                     /translation="MERGTASGGASLLKEFHPVQTLQQVENYTALSERASEYLLAVIR
                     SKPNAVICLATGATPLLTYHYLVEKIHQQQVDVSQLTFVKLDEWVDLPLTMPGTCETF
                     LQQHIVQPLGLREDQLISFRSEEINETECERVTNLIARKGGLDLCVLGLGKNGHLGLN
                     EPGESLQPACHISQLDARTQQHEMLKTAGRPVTRGITLGLKDILNAREVLLLVTGEGK
                     QDATDRFLTAKVSTAIPASFLWLHSNFICLINT"
BASE COUNT          558 a          569 c          606 g          620 t
ORIGIN      
        1 cgcccgataa tcgtttgtac cctaactggc gctattctcg gtgatattca gactggctta
       61 attaccggtg gtctgacaga gttggctttc gccggattaa cccctgcagg tggtgttcag
      121 ccgcccaacc cgattatggc gggtctgatg accaccgtca ttgcatggtc tacgggcgtt
      181 gatgccaaaa cagcaattgg tcttggcctg ccgtttagtt tgttaatgca gtacgtcatt
      241 ctgttcttct attccgcttt ctcattattt atgaccaaag ccgataaatg cgcgaaagag
      301 gcggatacgg cagcgttttc ccggcttaac tggacaacga tgctcatcgt cgcttcagcg
      361 tatgcggtga ttgctttcct ctgtacttac ctggcacagg gggcgatgca ggcgctggtg
      421 aaagcgatgc ccgcctggct gacccacggc tttgaagtgg ctggcggtat tctgcctgcc
      481 gttggttttg gcttgctgct gcgcgtaatg ttcaaagcgc aatatatccc ttacctgatc
      541 gccggtttcc tgtttgtttg ctacatccag gtcagcaacc tgttgccggt tgccgtactg
      601 ggcgcaggct ttgcggtgta tgagtttttc aatgcgaaat cccggcagca agcgcaaccg
      661 cagcccgttg ccagtaaaaa tgaagaagag gactacagca atgggatctg aaatcagtaa
      721 aaaagatatc acccgtctgg gctttcgttc gtcgctgctg caagcgagct ttaactacga
      781 aaggatgcag gcgggcggtt ttacctgggc gatgttgccg atcctgaaaa agatttataa
      841 ggacgacaaa ccgggcttaa gcgcggcgat gaaagataac ctcgaattta ttaataccca
      901 cccgaatctg gtcggattcc tgatggggtt attaatttcg atggaagaaa aaggagaaaa
      961 ccgcgacacc attaaaggcc tcaaagtggc actgtttggc ccaatcgccg ggattggcga
     1021 tgcgattttc tggtttactt tgttgccgat tatggcggga atttgctcat catttgccag
     1081 ccagggaaac ctgctggggc cgattctatt tttcgccgtt tacctgctta tctttttcct
     1141 gcgcgtcggc tggacccacg tcggttattc agtcggcgtg aaggcgatcg ataaagtgcg
     1201 agagaactcg cagatgattg cccgttcggc aaccatcctc gggatcacgg taatcggcgg
     1261 gctgatcgct tcgtatgtgc atattaacgt ggtgacatcg tttgccatcg acaataccca
     1321 cagcgttgcg ctgcagcagg atttcttcga taaagtcttc ccgaacattt taccgatggc
     1381 ctacaccctg ctgatgtatt acttcctgcg ggtgaaaaaa gcgcatccgg tgctgttaat
     1441 cggcgtgact tttgtgctct ctattgtttg ttccgcattc ggcattttgt aaatggaacg
     1501 aggcactgcg tctggtggtg cctctttact taaggaattt catcctgtgc aaacccttca
     1561 gcaagttgaa aactatacgg cgttaagtga acgtgccagc gaatatttat tggccgtgat
     1621 ccgtagcaaa ccgaatgccg tgatttgcct ggcgaccgga gccacgccat tactgacgta
     1681 tcattatctg gtagaaaaaa tccaccagca gcaggttgat gtcagccagc tcaccttcgt
     1741 gaagctcgac gaatgggtgg atctgccatt aacgatgcca ggcacctgcg aaactttcct
     1801 gcaacagcat atcgtgcagc cgctggggct acgtgaagac cagctcatca gctttcgctc
     1861 cgaagagata aatgagacag agtgcgaacg ggtaacgaac ctgattgcgc gcaaaggcgg
     1921 tctggattta tgcgttctcg gattggggaa aaacggtcat cttgggctga acgaaccggg
     1981 agaaagcctg caaccggcct gccatatcag tcaacttgat gccagaacac agcaacatga
     2041 gatgttaaaa accgcgggtc gccccgtgac tcgtgggatc accttaggcc tgaaggatat
     2101 tctcaatgcc cgcgaagttt tgttactggt gactggcgaa ggaaagcagg atgcgacaga
     2161 tcgttttctc acggctaaag tctccaccgc tatcccggct tcatttttat ggctgcacag
     2221 taactttatt tgtttaatta acacctaacc agatgaaaaa tttgctcaaa atgtttaaat
     2281 taacttatgt aacagtcacg cattatatta aataacattt gactgggttg aacataacgc
     2341 cgatagcaaa agg
//
LOCUS       DAPOAV010000237         2343 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.244, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000237 DAPOAV010000000
VERSION     DAPOAV010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2343
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.244"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(83..484)
                     /gene="pemK"
                     /locus_tag="RN951_004613"
     CDS             complement(83..484)
                     /gene="pemK"
                     /locus_tag="RN951_004613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001398199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin
                     endoribonuclease PemK"
                     /protein_id="HDX2529474.1"
                     /translation="MLKYQLKNENGWMHRRLVRRKSDMERGEIWLVSLDPTAGHEQQG
                     TRPVLIVTPAAFNRVTRLPVVVPVTSGGNFARTAGFAVSLDGVGIRTTGVVRCDQPRT
                     IDMKARGGKRLERVPETIMNEVLGRLSTILT"
     gene            complement(417..674)
                     /gene="pemI"
                     /locus_tag="RN951_004614"
     CDS             complement(417..674)
                     /gene="pemI"
                     /locus_tag="RN951_004614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000557619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PemI"
                     /protein_id="HDX2529475.1"
                     /translation="MHTTRLKRVGGSVMLTVPPALLNALSLGTDNEVGMVIDNGRLIV
                     EPYRRPQYSLAELLAQCDPNAEISAEEREWLDAPATGQEEI"
     gene            complement(767..1420)
                     /locus_tag="RN951_004615"
     CDS             complement(767..1420)
                     /locus_tag="RN951_004615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001757010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDX2529476.1"
                     /translation="MIQTRNQYLQFMLVMLAAWGISWGARFVMEQAVLLYGSGKNYLF
                     FSHGTVLMYLLCVFLVYRRWIAPLPVVGQLRNVGVPWLVGAMAVVYVGVFLLGKALAL
                     PAEPFMTKLFADKSIPDVILTLLTIFILAPLNEETLFRGIMLNVFRSRYCWTMWLGAL
                     ITSLLFVAAHSQYQNLLTLAELFLVGLITSVARIRSGGLLLPVLLHMEATTLGLLFG"
BASE COUNT          599 a          612 c          582 g          550 t
ORIGIN      
        1 gaatcaccag aatggtggga caacagcggt tttagtgccc taaatcgtac gttttcatcc
       61 agttgcccct caaaccccat gttcaagtca gaatagtgga caggcggcca agaacttcgt
      121 tcatgatagt ctccggaacc cgttcgagtc gttttccgcc ccgtgctttc atatcaattg
      181 tccggggttg atcgcaacgt acaacacctg tggtacgtat gccaacacca tccaacgaca
      241 ccgcaaagcc ggcagtgcgg gcaaaattgc ctccgctggt tacgggcaca acaacaggca
      301 ggcgggtcac gcgattaaag gccgccggtg tgacaatcag caccggccgc gttccctgct
      361 gctcatgacc tgcggtagga tcaagcgaga caagccagat ttcccctctt tccatgtcag
      421 atttcctcct gaccagtcgc cggtgcatcc agccattctc gttcttcagc tgatatttca
      481 gcattcggat cacactgtgc cagtagctca gccagtgaat attgcgggcg tctgtacggc
      541 tcaacaatca gccggccatt atcaatgacc atgccaactt cattatctgt gcccagagac
      601 agcgcattca gcagtgccgg tgggacggtc agcataactg agccgccaac cctcttcagt
      661 cgggtggtat gcattcttca cctccataaa agttatattt aaatataaca tccactaaaa
      721 aaacacacca ggctttaacg cacaatgttt aataaaaata taactttcaa ccaaacagta
      781 aacccagcgt ggttgcttcc atatgcagca ataccggcag cagcaggcca ccacttctga
      841 tcctggccac tgatgtaatc aaccccacca ggaacagttc tgccagtgtc agcaggttct
      901 gatactggct gtgcgcggcg acgaacaaca acgacgttat cagcgccccc agccacatcg
      961 tccagcagta ccgtgaacgg aagacgttca gcataatccc ccggaacagc gtttcctcat
     1021 tcaacggggc aaggataaag atggtcagca acgtcaggat cacgtcaggt atggacttat
     1081 cggcaaaaag tttcgtcata aatggctcag caggcagagc cagcgcctta ccgagcagaa
     1141 atacaccgac atacaccacg gccatcgcac cgaccagcca cggtacgcca acgttgcgca
     1201 gctgaccaac gaccggtagc ggagctatcc aacggcggta taccaggaaa acacacagca
     1261 ggtacatcag aacagtacca tgactgaaga acaaatagtt ttttcctgat ccataaagca
     1321 gaacggcctg ctccatgaca aatctggctc cccaactaat gccccatgca gccagcataa
     1381 ccagcataaa ctgcagatat tgattacgtg tttgaatcat tgcatcgcct gtaaattttt
     1441 aacttgtcct atttttgtca ttaccacgta tatacacatg tataacaatt cagatatcgt
     1501 taccaggata tgccgcatca gcggcatgga aggcggcact ctgttgtttc atatgataca
     1561 ggagtaaaac cgccgaagcc cggcgtaagc cggtactgat tgatagattt caccttaccc
     1621 atccccagcc ctgccagacc atacccgctt tcagccatga gagagcttct gtgcgcggtc
     1681 ggagtggtcc cgacgagggt ttacccgaag tcggggcgta tctccgcgtt agcgggccgt
     1741 gagggccgct tacgagcgtg tactgagaac ttccagcgag aagactgaca gcgatgaaga
     1801 tgtagttaca acattcataa ttaaaagcga ctctgttccg gcccgaaggg ccggggcggg
     1861 gccgcttttc agttatgagg gaggggcttt gtggtttcag ttctgcgctg gaccggggtt
     1921 tttctggagg ttgtttttgt gtgttgtaac taaagtggct ccggtcgggg cccgccgctt
     1981 gcggtgggag gtgcatatct gtctgtccac aggacaggca gtgaataggt tttcttttta
     2041 aatgaatgta attaagtagt ttaaaggaga tataaacagg tgtttaaaag atacattgca
     2101 ccctgtaaga ctggcggctg gcgctttatg acatgaacgg ttgtaacctt atggggaagt
     2161 cccttgcagt taaatgtgga taagcaaaat tccccgtcgc tgaggcgtat tttgtattaa
     2221 aaacaggggg aatcggatgc tccagaaggt ggatgatgag attgtttttt gcatgcgacg
     2281 ctgttttttt gtgcaccggc gggcttcagg cgtgcggatg cctccggcgc aggccggatt
     2341 att
//
LOCUS       DAPOAV010000238         2339 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.245, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000238 DAPOAV010000000
VERSION     DAPOAV010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2339
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.245"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..273)
                     /locus_tag="RN951_004616"
     CDS             complement(<1..273)
                     /locus_tag="RN951_004616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDX2529477.1"
                     /translation="MGHRAAIYCRVSTADQSCERQEFDLRAFAGCAGYDVVGIFKETG
                     SGTKLDRAERKKVLALAQSRQIDAILVTELSRWGRSTLDLLNTLREL"
     gene            368..>2339
                     /locus_tag="RN951_004617"
     CDS             368..>2339
                     /locus_tag="RN951_004617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn5403 family transposase"
                     /protein_id="HDX2529478.1"
                     /translation="MSRRHIFTERQRAALFDLPTDELSLLKFYTLGDDDLENIRQRRR
                     PENRIGFALQLCALRYPGRALAPGEMIPREVLSFVGAQLGVPADALLTYATRRQTRQQ
                     HMDTLREIYGYKTFTGRGARDLREWTFGQAEDARSNEDLAHRFIVRCRETSTILPAVS
                     TIERLCADALVAAERRIETRIAENLTADVRDHLDKLLSEMLAGNISRFIWLRNFEVGN
                     NSAAANRLLDRLEFLRTLNINHSALASIPAHRIARLRRQGERYFTDGLRDITSDRRWA
                     ILAVCVVEWEAAIADAIVETHDRIVGKTWREAKRQHDETISGSKATLTDTIRTFTALG
                     ASLLEARSDGTPLEMAVASSVAWDRLAQLVATGTQLSNTLADEPLAYVGQGYHRFRRY
                     APRMLRCLKLEAAPVAGPLVAAALSIGEMKGVASPERRFLRPSSKWNRHLRAQEKGDT
                     RLWEVAVLFHLRDAFRSGDVWLAHSRRYGDLKQVLVPMIAAQENAKLAVPSNPQDWLA
                     DRKARLTIALKRLARAARNGTIPHGSIEDGTLRIDRLTADVPDGAEALILDLYRRMPS
                     VRITDMLLEVDAALGFTDAFTHLRTGAPCRDRIGLLNVLLAEGLNLGLRKMAEATNTH
                     DYWQLSRLARWHVESEAMNQALAIVVAAQGKLP"
BASE COUNT          498 a          653 c          666 g          522 t
ORIGIN      
        1 cagttcacgt agcgtattga gcagatcgag cgtcgagcgc ccccaccggg aaagctcagt
       61 gaccaggatt gcatcaattt gtctggactg ggcaagcgcc aggactttct ttcgctcggc
      121 ccggtcgagt ttagttcctg aacctgtttc cttaaatatt cccaccacgt cgtagccggc
      181 acagccggcg aaggctcgca gatcaaattc ctggcgttca caagactgat ccgctgttga
      241 aacccggcag taaatggcgg cacgatgtcc caattgaacc ctcctggatt tttgtatcgg
      301 aacgccctga tttatatggg ctggctgttg tccaaaacag actatacttc aaaagggacg
      361 aatttgtatg tcacgacgcc atattttcac cgaacggcag cgagcagcgc tgttcgatct
      421 gcccacggac gaactgtcgc tactgaagtt ctacacgctg ggcgatgatg acctggaaaa
      481 cattaggcag cgccgcagac cggaaaacag gattggcttt gccctgcaac tttgtgcctt
      541 acgatatccg ggccgtgcac tggctcctgg tgagatgatc ccgcgtgaag tcctttcctt
      601 cgtcggtgct cagcttggag ttccggctga tgcgcttctc acttatgcca cacggcgcca
      661 aacccgtcag cagcacatgg acacgctgcg cgaaatttac ggctacaaga ccttcacggg
      721 ccgtggtgcc cgtgatctgc gggagtggac tttcggccag gccgaagatg ccagatcaaa
      781 cgaggatctt gctcatcgtt ttattgtgcg gtgtcgggaa acttccacca ttctgcccgc
      841 agtatcgaca atcgagcgct tgtgcgcgga tgctctggtc gccgctgagc ggcggattga
      901 aacgcggatt gcggaaaatt taacagcgga tgttcgcgat cacctggaca aacttctgag
      961 tgaaatgctc gccggcaata tcagtcgttt catctggctt cgcaacttcg aggttggtaa
     1021 caactcggct gctgctaacc gtttgctcga caggctcgaa tttctgcgta ccctgaatat
     1081 caatcatagt gctttggcca gcatacctgc ccatcgcatt gcccggctgc gtcggcaggg
     1141 tgaacgctac ttcaccgacg gtttgcgtga catcacttcg gaccgccgct gggcgatcct
     1201 tgccgtctgt gttgtggagt gggaagcggc gattgctgat gccatagtcg aaacccatga
     1261 caggatcgta ggaaaaacct ggcgggaagc gaagcgccag catgacgaaa caatttccgg
     1321 ctctaaagcc acactcacgg atacgatccg taccttcacc gcgctgggag cttcgttgct
     1381 tgaggcccgc agtgacggaa ccccgctgga gatggctgtc gccagttcgg ttgcatggga
     1441 ccggctcgct caactggtag cgacagggac tcaactcagc aacacgctag ccgatgagcc
     1501 tcttgcatat gtcgggcagg gataccatcg ctttcgtcgt tatgcgcccc gcatgttgcg
     1561 ctgtctgaag ctcgaagccg cgccggtcgc cggaccattg gtagcagcag ctttgtcgat
     1621 cggagagatg aaaggtgttg catcgccaga aaggcgtttc ctgcggccca gctccaaatg
     1681 gaaccgtcat ttacgagctc aggaaaaagg agatacccgt ctttgggaag tggcggtact
     1741 ctttcacctc cgggatgctt ttcgttccgg agatgtctgg ctcgctcatt cgcgccgcta
     1801 tggtgacctc aagcaggtac tggtgccgat gatcgcggcg caggaaaatg caaaactggc
     1861 cgtgccttcc aacccacagg attggctggc agacagaaag gcgcgactca cgatcgctct
     1921 taagcggctg gcccgggctg cccgtaacgg cactattccg cacggtagca tagaagatgg
     1981 aacgttgcgg atcgacaggt tgacagcaga cgtgccggat ggtgccgagg cactcatact
     2041 ggatctgtat cgccgaatgc cgtccgttcg gattaccgac atgctgcttg aagttgatgc
     2101 agcccttggt ttcacagatg cgtttaccca tctgagaacc ggggctccat gtcgcgaccg
     2161 gatcggtctg ctcaacgtcc tgctcgctga agggctcaat ctgggcctgc gtaagatggc
     2221 ggaagctaca aacacgcatg attactggca gctctcacgc cttgcccgct ggcatgttga
     2281 aagcgaagcc atgaaccagg cattggcaat tgtggtggcc gcgcagggta aactgccga
//
LOCUS       DAPOAV010000239         2252 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.247, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000239 DAPOAV010000000
VERSION     DAPOAV010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2252
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.247"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            583..1065
                     /locus_tag="RN951_004618"
                     /pseudo
     CDS             583..1065
                     /locus_tag="RN951_004618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001609301.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VENN motif pre-toxin domain-containing protein"
     gene            complement(1011..1456)
                     /locus_tag="RN951_004619"
                     /pseudo
     CDS             complement(1011..1456)
                     /locus_tag="RN951_004619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052675.1"
                     /note="RepA; frameshifted; incomplete; partial in the
                     middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="incFII family plasmid replication initiator
                     RepA"
     gene            complement(1449..1523)
                     /gene="tap"
                     /locus_tag="RN951_004620"
     CDS             complement(1449..1523)
                     /gene="tap"
                     /locus_tag="RN951_004620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001370046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA leader peptide Tap"
                     /protein_id="HDX2529479.1"
                     /translation="MPGKVQDFFLCSLLLRIVSVGWCD"
     gene            complement(1759..2016)
                     /gene="repA"
                     /locus_tag="RN951_004621"
     CDS             complement(1759..2016)
                     /gene="repA"
                     /locus_tag="RN951_004621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication regulatory protein RepA"
                     /protein_id="HDX2529480.1"
                     /translation="MSQTENAVTSSSGKKRPYRRGNPVPARERQKASLARRSATHKAF
                     HAVIQLRLKEKLSELADEDGITQAQMLEWLIESEVKRRKSL"
BASE COUNT          624 a          511 c          565 g          552 t
ORIGIN      
        1 agtaaaaaaa ctgtagcgtg aataattatg aaataattgc aatttaactt ttcttggctt
       61 aataaaaggc tgtaaatagt tatgaaatca taaagaaaaa ttattaatgt gataaaatgt
      121 gatatgttct caggttttgt gattttattt tataattctg gtggttgtgt tggcgttatc
      181 acacgctcga aatgaagtta tgcataaccg ctgcataatt acctgtgtat gattaacaat
      241 gatttaacac ccttcccgat aaacatgagc tcgcttagat gtcacaggaa aagggctagt
      301 atggcagcac tggttttcgt atgaaagaaa gataaaacat tgccttatat ctaaggcttc
      361 ttgattatcg gtaacatcca ccatctccag ccatagctgg caggtggtga cgttggtgca
      421 gtactggcgg gagcttcggc tccggaactg gcatacctgc tgaaatcaac agaaaaagac
      481 ccggcagtaa aggccattgc tcacgccatt ctgggcggtg cagtagcagc aatgcagagt
      541 aataatgttg ctgctggtgc agcaggcgca gcaacaggag agctggcagc cagagcgatc
      601 ggaatgctgt atccgggagt gaagctgtct gacctcagtg aagagcagaa gcagacgata
      661 agtacgctgg caaccgtgtc agcagggctg accggcggtc taaccggaaa cagcaccgca
      721 tcagctgcag tgggagcaca cagagcggga agaatgctgt tgagaataac tacctgagcg
      781 tgtctgaaaa gacagaactt gagatagcaa aacagacgat taaaaacagt aaagatccgg
      841 cagagcgtga aaaggcacag cagaaatatg atgcattgct tgaaaaagat attcagtgat
      901 aaggaggtta ttgctgcctg tagtaatggt aatgcgggta gttcagcgtg tgccagcgca
      961 agactgaaag ctattgcgtc gaaagaaggg tacgaagatg gcccttataa cgagatatcg
     1021 gtcggaatgt tgcagccaat aagcgggtca tattccgtct ggtagctaat cagccccagc
     1081 tctgacagga acgtcagggc acgggtggca cgggtgatgg agagtgttcc ggcagcagac
     1141 tccgtcgcca gcccgcactc aatggccagc gtggtgatgg agcactggac acggttggcc
     1201 agcgggtcat agtggaaaca cagcccctgc agcagcgcat caatagcccg tcgacgcagc
     1261 accggtggca tgcgccgacg cagtcccttc gaacgggcat gcgccacatg aatagcgcaa
     1321 tcaaaacggg aggtgaagcc accgcctttt ccatcagttt ttcgcagaac ttcagcgttc
     1381 ctgcaccttc acggggtgta aacaccggat tcgggttctt tacctggcgg taatacgttt
     1441 gttgaagatc agtcacacca tcctacgctt acaatgcgca gaaggagtga gcacagaaag
     1501 aagtcttgaa cttttccggg catataacta tactccccgc atagctgaat tgttggctat
     1561 acggtttaag tgggccccgg taatcttctc ttagtcgcca aacctggtga agattatcgg
     1621 ggtttttgct tttctggctc ctgtaaatcc acatcagaac cagttccctg ccaccttacg
     1681 gcgtggccag ccacaaaatt ccttaaaacg atcagcaatc taacatctca tcactgaaac
     1741 agcaagaaac gcaaatactc acaaagattt tctgcgctta acctctgact ctatcagcca
     1801 ctcaagcatc tgtgcctgag tgatcccgtc ttcatcagca agctcactta acttttcttt
     1861 cagtcgaagc tgaatgacgg catgaaacgc tttatgagtg gcactccttc ttgcaagaga
     1921 cgctttttgt cgttctctcg caggaacagg attacccctt ctgtaaggtc gtttttttcc
     1981 cgatgaggaa gtcactgcat tttctgtctg cgacatctcg cctcctcaat aatcaaacag
     2041 agatcgtttc gcagaggata ctacagtttt ttgaaatcag cgacttgaaa gttgtgacga
     2101 tgatcggtgt tggcgcacaa atcatgtctg attacaaccg tttaatgtga ttttgataat
     2161 gaaatgactg aaaagcagga aatgccttaa ccaggatgcc ggccccgggc gggaccggct
     2221 gtttctggca tgtcgggtgt ctgcccctga aa
//
LOCUS       DAPOAV010000240         2226 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.248, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000240 DAPOAV010000000
VERSION     DAPOAV010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2226
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.248"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..312)
                     /locus_tag="RN951_004622"
     CDS             complement(<1..312)
                     /locus_tag="RN951_004622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017694593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529481.1"
                     /translation="MKMTKADFGVTIDDTLITDFRDVVNEGEFAYSYFINRNGKNQFS
                     PICSCMDWISVSVRNLMNFPELSEDIDVKAMQVYSLISSIDIAVEALQQLHRIIESDD
                     KL"
     gene            927..2141
                     /locus_tag="RN951_004623"
     CDS             927..2141
                     /locus_tag="RN951_004623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001515790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDX2529482.1"
                     /translation="MKLNARQVETAKPKDKPYKMADGGGLYLLVKTNGSRYWRLKYRI
                     DGKEKLLALGVYPDVSLADARAKRDEARKGIAGGIDPLELKKEHKAEREAQVKNTFQQ
                     IALEWHSMKVKKWSVGYASDILEAFNKDIFPFLGQRPVAEIKPLELLNVLKKIEARGA
                     TEKAKKVRQRCGEVFRYAIVTGRAEYNPAPDLTSAMQGHESTHYPFLTTEELPAFFKA
                     LAGYSGSELMVLAARLLILTGLRTGELRGALWSEIDSEKALWEISAERMKMRRPHIIP
                     LSTQALAIIEKIRAMTGQFPLLFPGRNDPSKTMSEASINQVFKRIGYTGRVTGHGFRH
                     TMSTVLHEQGYNTAWIETQLAHVDKNAIRGTYNHAQYLDGRREMLQWYADYMVSLEKG
                     GNVVQGTFNRCG"
BASE COUNT          630 a          487 c          526 g          583 t
ORIGIN      
        1 taacttatca tcactctcaa tgatgcggtg aagctgctgc aacgcctcca cagcaatatc
       61 aatagatgat ataagggagt aaacctgcat ggccttgaca tcaatatctt ccgacagctc
      121 agggaagttc atcagattgc gaacagaaac gcttatccaa tccatgcacg aacagatagg
      181 gctgaactgg tttttaccat ttctgtttat gaagtagctg taagcaaact ccccttcatt
      241 aaccacatct cgaaaatcag ttattaaagt atcatcaata gttacaccaa aatctgcctt
      301 ggtcatcttc atggaaatca ctttcaaatc agcacactta gaggttgatt gtgaccgtta
      361 tcataggcaa aaacaattca gtaggttgac cagccccccc cataactcaa aattgctcga
      421 tttaagtatg cattccaact tccgctcctc gctcataaca gacattcact acagttatgg
      481 tagaaggtat gcatgctggg tggggaaagt atgaaggaaa agaaggctgc tgtgtcgttt
      541 gacatcactg caatcttctt attggttatg cgggtcgtag tgggacaaaa ctgagacaca
      601 taaggcctag caatggcttg caaggcttta catgttttga tgtggtggga cttgtgagcg
      661 cagtgttgat ggggtaatgc tttgaattag aagcggattc ttataattcg taatgcgaag
      721 gtcgtaggtt cgactcctat tatcggcacc atcctaccta ttttaacgtc tccttaagtc
      781 tactcaaata ccctttaaac ccttataata cgcggtttca cggcccttgt tgtctctgct
      841 cgtctactca cgttcacaga aatctacggt gagttggggg tatcaatggg ggtattcgct
      901 gttcggtcta aaggagatac ccccagatga agctcaatgc cagacaggtc gagactgcca
      961 agcccaaaga taaaccctac aagatggctg atggtggtgg cctctactta ttggttaaaa
     1021 ctaacgggtc acgctactgg cgtttaaagt atcgtatcga tggaaaggaa aagttattgg
     1081 cgctgggggt atatcccgat gtgtctttgg ctgatgccag agcaaagcgt gatgaagctc
     1141 gaaaaggtat cgctgggggt atcgatcctt tagagcttaa gaaagaacat aaagctgagc
     1201 gtgaagcgca ggtcaaaaac acctttcagc aaattgcgct cgaatggcac agcatgaaag
     1261 tgaaaaaatg gtcagttggg tatgcctctg acattctcga agctttcaat aaagatattt
     1321 ttccttttct tggtcaacgg cctgttgcgg aaattaagcc attagagctt cttaatgtgc
     1381 ttaaaaaaat cgaagccaga ggtgcaacag agaaagcaaa gaaagtgcgc caacgatgtg
     1441 gtgaagtgtt tcgctatgcc atcgtgacag gcagagccga gtataatccc gctcctgatc
     1501 tcaccagtgc catgcagggg catgaatcta cacattaccc gttcctgacc accgaagagc
     1561 ttcctgcctt ttttaaagcc cttgctggct actctggtag tgaattgatg gtgttggcag
     1621 caagattatt gatccttact ggcctaagaa cgggtgaatt gcgtggtgcc ttatggtcgg
     1681 aaatcgattc cgagaaagcg ctatgggaaa tttctgctga acgcatgaaa atgcgtcgcc
     1741 ctcatatcat cccgctatct acccaagcgt tagccattat cgaaaagatc agagcaatga
     1801 cgggacaatt ccctttgctg tttccgggcc gcaatgatcc aagtaagacc atgagcgaag
     1861 ccagtatcaa tcaggtattt aagcgaatcg gctatacagg acgggttacg ggtcacggct
     1921 tccgtcatac catgagcacc gttcttcatg aacagggcta caacaccgca tggattgaaa
     1981 cccaactagc ccatgttgat aagaatgcta tccgtggcac ctacaaccat gcgcaatatc
     2041 tcgatggcag acgcgagatg ctgcaatggt atgccgacta catggtaagc cttgagaaag
     2101 gcggtaatgt cgtacaggga acgtttaatc ggtgtgggta aggataactg ctgatgaaag
     2161 aagggttatg tcttaacggc catagccctt tttcttggct aatgcagata agaattaagt
     2221 cagaat
//
LOCUS       DAPOAV010000241         2188 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.249, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000241 DAPOAV010000000
VERSION     DAPOAV010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2188
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.249"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            18..386
                     /locus_tag="RN951_004624"
     CDS             18..386
                     /locus_tag="RN951_004624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017880027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529483.1"
                     /translation="MANFNPGPRTAIAAVRDSKNDIETWKKNGIRREEIVTVLNERYG
                     LNISLVAFDKALYRLRKSTDEPSLADVDSVSAAETNFSEASGPDNGFFLSGNDFMRAE
                     EESQRVVESFRDSLSRKKGF"
     gene            471..1454
                     /locus_tag="RN951_004625"
     CDS             471..1454
                     /locus_tag="RN951_004625"
                     /inference="COORDINATES: protein motif:HMM:NF012745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDX2529484.1"
                     /translation="MKKKFSIIVPVYNVEKYLRECIQSVLDQDFNDYEIICVNDGSTD
                     GSLDIILSFDDQRIKVINQENKGLSVARNVAIESSTGEYIWFLDSDDKISHGSLKLID
                     KITNEKNYGIIFFNTHVFFDTPELKKKGWHDYKRSTFGEMDALTFFEKEMTNKKLIVS
                     ACCYVFRRELLNGNAFIPHIYHEDNHFIATLIFDNYSTICLSLDEALYLRRVRNDSIM
                     TSKKSMRHIIGYSTCIDELTKYKKTKGIQNKSFDRFVNGMVLSLFSIAETIKTKEAMN
                     YVVRYKKHPDLSFKDRALINYPLIKKTYLKLKNGKVFNYLRNGIINKKSNP"
     gene            complement(1913..>2188)
                     /locus_tag="RN951_004626"
     CDS             complement(1913..>2188)
                     /locus_tag="RN951_004626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="HDX2529485.1"
                     /translation="ERTLATLERLLSLLSAFEVVVWMTDGWPLYESRLKGKLHVISKR
                     YTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVIGHYLNIKHYQ"
BASE COUNT          719 a          378 c          459 g          632 t
ORIGIN      
        1 gacattatgg gcggtatatg gcgaatttta accctggtcc aagaacagcc attgcagctg
       61 tcagggattc caagaacgat atagaaacct ggaagaaaaa tggtattcgt agggaagaga
      121 ttgtgactgt gctgaatgaa cgttacggcc tgaatatctc actggttgcg tttgataagg
      181 ctctttacag attgagaaaa agtacagatg aaccgtctct tgctgatgtg gattctgtgt
      241 ctgctgcaga aacgaatttc tctgaagcca gtgggcctga caatggtttt tttctgtccg
      301 ggaatgactt catgcgagca gaagaagaat ctcaaagagt ggttgagtca ttcagagata
      361 gccttagcag gaagaaagga ttctgattta ttcaacaaag ccgttgataa atcgcattcc
      421 ataaataaca acttgatgtt agtataacta aatattgttt ggagattact gtgaaaaaaa
      481 aattttcgat aatagtacct gtatataacg ttgaaaaata cttaagggaa tgtattcaat
      541 cagtattaga tcaggatttt aacgactatg agataatctg tgtaaatgat ggttcaacag
      601 atggcagtct agatatcata ctgtcatttg atgaccaaag aatcaaagta ataaatcagg
      661 aaaataaagg cctgtcggtg gcaagaaatg tcgccattga atcatcaact ggtgaatata
      721 tatggttttt agatagtgat gataaaatat cacatggaag tctaaagtta atagacaaga
      781 taaccaatga aaaaaattat gggattattt tctttaatac acatgttttt tttgacactc
      841 cagaactgaa aaaaaaaggc tggcatgatt ataagcgttc aacatttggt gaaatggatg
      901 cattaacttt ctttgaaaaa gaaatgacga acaaaaaact aatagtgtca gcatgctgct
      961 atgtttttag aagggaatta ttaaatggca atgcattcat tccgcatata tatcatgagg
     1021 ataatcactt tatagcaacc ctgatttttg acaattattc aactatatgc ctctcgttgg
     1081 atgaggcgtt atatcttagg agggtaagaa atgattccat aatgacgtct aaaaaatcaa
     1141 tgaggcacat cattggatat tcaacatgca tcgatgagct tacgaagtat aaaaaaacaa
     1201 aaggcataca aaacaagagc tttgatagat ttgtgaatgg aatggttttg tcgttattct
     1261 ctatagcgga aacaataaaa acaaaggaag caatgaacta tgtggtgaga tataaaaaac
     1321 accccgacct atcatttaaa gatagagcat taattaatta cccattaatt aaaaagactt
     1381 atttaaaact aaaaaacggg aaggtgttta attacctaag gaatggcatt attaataaaa
     1441 aaagcaaccc ttaataaaag caaagcgata attaataaag gtttttcttt gttgaataaa
     1501 taagatttcg gataggtatc cccgtgacgg gttgggtttt caggcgatac gcacgctttc
     1561 cggggctttg ttgaataaat cgaacttttg ctgagttgaa ggatcagatc ggggtcagtt
     1621 tggagatcgg aaatttttgt acgttaagcg cattatttaa ccaatcttgg ttcgtaaggg
     1681 gttgattttg cgtcagtggc tatcgctttt aagttgtcgc tcttgcagta tcgcatttag
     1741 gttatccgat taaggtcaaa cctctgaaaa tgccgtatag cgcgggagta caccctattg
     1801 ctataggtaa gtctgttcaa aaaacaggct taccgtacaa taattctcta tatccaaact
     1861 aaccccagat cacgcatctt cccgacaacg cagaccgggt aatgactcca acttactgat
     1921 agtgttttat gttcagataa tgcccgatga ccttgtcatg cagctccacc gattttgaga
     1981 acgacagtga cttccgtccc agccttgcca gatgttgtct cagattcaga ttatgtcgct
     2041 caatgcgctg cgtatatcgc ttgctgataa cgtgcagctt tcccttcagg cgtgattcat
     2101 acagcggcca gccatccgtc atccatacca cgacctcaaa ggccgacagc aggctcagaa
     2161 gacgctccag tgtggccaga gtgcgttc
//
LOCUS       DAPOAV010000242         2183 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.250, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000242 DAPOAV010000000
VERSION     DAPOAV010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2183
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.250"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..440)
                     /locus_tag="RN951_004627"
     CDS             complement(<1..440)
                     /locus_tag="RN951_004627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002075262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HDX2529486.1"
                     /translation="MTNYFDSPFKGKLLSEQVKNPNIKVGRYSYYSGYYHGHSFDDCA
                     RYLFPDRDDVDKLIIGSFCSIGSGASFIMAGNQGHRYDWASSFPFFYMQEEPAFSSAL
                     DAFQKAGNTVIGNDVWIGSEAMVMPGIKIGHGAVIGSRSLVTKDV"
     gene            complement(578..1408)
                     /locus_tag="RN951_004628"
     CDS             complement(578..1408)
                     /locus_tag="RN951_004628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxacillin-hydrolyzing class D beta-lactamase
                     OXA-1"
                     /protein_id="HDX2529487.1"
                     /translation="MKNTIHINFAIFLIIANIIYSSASASTDISTVASPLFEGTEGCF
                     LLYDASTNAEIAQFNKAKCATQMAPDSTFKIALSLMAFDAEIIDQKTIFKWDKTPKGM
                     EIWNSNHTPKTWMQFSVVWVSQEITQKIGLNKIKNYLKDFDYGNQDFSGDKERNNGLT
                     EAWLESSLKISPEEQIQFLRKIINHNLPVKNSAIENTIENMYLQDLDNSTKLYGKTGA
                     GFTANRTLQNGWFEGFIISKSGHKYVFVSALTGNLGSNLTSSIKAKKNAITILNTLNL
                     "
     gene            complement(1539..2093)
                     /locus_tag="RN951_004629"
     CDS             complement(1539..2093)
                     /locus_tag="RN951_004629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003159191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoroquinolone-acetylating aminoglycoside
                     6'-N-acetyltransferase AAC(6')-Ib-cr5"
                     /protein_id="HDX2529488.1"
                     /translation="MTNSNDSVTLRLMTEHDLAMLYEWLNRSHIVEWWGGEEARPTLA
                     DVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGRWEEETDPGVRGIDQL
                     LANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAIRCYEKAGFERQGTV
                     TTPYGPAVYMVQTRQAFERTRSDA"
BASE COUNT          519 a          491 c          495 g          678 t
ORIGIN      
        1 acatcttttg tcaccaacga gcggctgcct atcaccgcac cgtgcccgat cttgattccg
       61 ggcatgacca ttgcctcaga gccgatccaa acgtcattgc caatgacagt attacctgct
      121 ttttggaagg catcgagtgc gcttgagaat gcaggttctt cctgcatata aaagaacggg
      181 aaagatgatg cccagtcgta ccgatgcccc tgattgccag ccatgataaa ggaagcccca
      241 ctcccgatag agcagaaact accgatgatc aacttatcaa cgtcatcacg gtccggaaac
      301 agataccgtg cgcagtcatc gaatgagtgc ccatgatagt agccagagta atagctgtac
      361 cgcccaactt tgatattggg gttcttcact tgctcagaaa gcagcttgcc tttgaagggg
      421 ctatcaaagt agttggtcat aagagatccc gcggtctgtg actttgccgt ctaacgtttg
      481 aaataagggg cgccgagcgc cagcgagggg agccaaaagc ttgcttttgg ccgtcccgac
      541 ttgattgaag ggttgggcga ttttgccatt agatttttta taaatttagt gtgtttagaa
      601 tggtgatcgc atttttcttg gcttttatgc ttgatgttaa attcgacccc aagtttcctg
      661 taagtgcgga cacaaaaaca tatttatgtc ctgatttgct tataataaac ccttcaaacc
      721 atccgttttg taaggttcta tttgctgtga atcctgcacc agttttccca tacagttttg
      781 tactattatc cagatcttgt agatacatgt tctctatggt gttttctatg gctgagtttt
      841 taactgggag attgtgatta ataattttac gcaggaattg aatttgttct tctggtgaaa
      901 tttttaagct actttcgagc catgcttctg ttaatccgtt gtttctttct ttatctccag
      961 agaagtcttg atttccataa tcaaaatctt tgagataatt cttgatttta tttaatccaa
     1021 ttttttgggt tatttcttgc gaaacccaaa caacagaaaa ttgcatccac gtctttggtg
     1081 tatgattgct gttccagatc tccattcctt tgggggtttt atcccatttg aatatggttt
     1141 tctgatctat tatttccgca tcaaatgcca taagtgataa tgcgatcttg aaagttgaat
     1201 ctggtgccat ttgcgttgca cactttgctt tattgaattg agcaatttca gcgtttgtgg
     1261 atgcatcgta aagtaaaaaa caaccttcag ttccttcaaa taatggagat gcaacagtag
     1321 agatatctgt tgatgcactg gcgctgctgt agataatatt tgcaattatt aaaaaaatag
     1381 cgaagttgat atgtattgtg tttttcataa taagtattgg tttggtaaag ggcttaattt
     1441 taacggctaa caattaatga ggctccgggt tcgcccaacg tttgacatga ggggcggcca
     1501 agggcgccag cccttggacg tccccctcga tggaagggtt aggcatcact gcgtgttcgc
     1561 tcgaatgcct ggcgtgtttg aaccatgtac acggctggac catatggggt ggttacggta
     1621 ccttgcctct caaaccccgc tttctcgtag catcggatcg ctcgcaagtt gctcggcgac
     1681 gggtccgttt ggatcttggt gacctcggga tcattgaaca gcaactcaac cagagctcga
     1741 accagcttgg ttcccaagcc tttgcccagt tgtgatgcat tcgccagtaa ctggtctatt
     1801 ccgcgtactc ctggatcggt ttcttcttcc caccgtccgt ccccgcttcc aagagcaacg
     1861 tacgactggg catacccaat cggctctcca ttcagcattg caatgtatgg agtgacggac
     1921 tcttgcgcta aaacgcttgg caagtactgt tcctgtacgt cagcaagtgt cgggcgtgct
     1981 tcttctccgc cccaccactc gacgatatga gatcgattta gccactcata gagcatcgca
     2041 aggtcatgct cagtcatgag gcgcagtgtg acggaatcgt tgctgttggt cacgatgctg
     2101 tactttgtga tgcctaactt tgtttttgcg ttgctcatga tgtctaactc ccaatttgtg
     2161 tagggcttat tatgcacgct taa
//
LOCUS       DAPOAV010000243         2050 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.251, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000243 DAPOAV010000000
VERSION     DAPOAV010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2050
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.251"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..867
                     /gene="rfaL"
                     /locus_tag="RN951_004630"
     CDS             <1..867
                     /gene="rfaL"
                     /locus_tag="RN951_004630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase RfaL"
                     /protein_id="HDX2529489.1"
                     /translation="DEDNESIGKIVLYSLVTGLGLRCLVELILYIQDYNKGIMPFSTY
                     EHRSISDSMVFLFPALLNLWLIKKTSYKIAFVIFSAVFLFLLLGTLSRGAWLAVFIVT
                     LLWLILNRQWKLLMLTSIVISVAAVGVFTYKGDHAGKDRLIYKLQQTDSSSRYTNGTQ
                     GTAWTLIMENPLKGYGYGDDIYHAIYNKRVVDFPSWKFRQSIGPHNVVLSIWFAAGLA
                     GLLALLYLYGSIIKETANATFKTVVVTPYNGQLLLFLTLVSFYIIRGNFEEVDLKPIG
                     LIVGLLLAMRNK"
     gene            complement(921..>2050)
                     /locus_tag="RN951_004631"
     CDS             complement(921..>2050)
                     /locus_tag="RN951_004631"
                     /EC_number="2.4.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000591812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lipopolysaccharide
                     N-acetylglucosaminyltransferase"
                     /protein_id="HDX2529490.1"
                     /translation="IFTVTPIFSIPPKGAAAVETWIYQVAKRLSIPVTIACIRNEGYP
                     TYTKVNDHCDIHYIGFSRVYKRLFQKWTRLDPVPYSQRILNTQPKNTDPKDSVIVIHN
                     SMKLYKQIRSRSPHAQLVMHLHNAFEPGELDKNAKIIVPSQFLFDFYSEKMPDANIAI
                     VPNGFCSESYEQNNTEDLRQKLNIDANDTVLLFAGRISPDKGCLMLMEAFNQLNKIQD
                     NLKLVIVGDPFASKKGEKAEYQKKVLDAAKAIGAQCIMAGGQPPEQMHNYYRLADLVV
                     VPSQVEEAFCMVAVEAMAAGKPVLASQKGGISEFVLEGITGYHLAEPMTSESILADIK
                     RVLADADRAQIAKNARNFVFSKYSWEHVTQRFEAQIQDWFG"
BASE COUNT          583 a          403 c          389 g          675 t
ORIGIN      
        1 gatgaagata atgaaagcat tggtaaaatt gtactatact cattagttac cggacttggc
       61 ttacgttgtc ttgttgaact tattctttat attcaggatt ataataaagg aataatgcca
      121 ttttccacct atgaacaccg tagtatttcc gattcaatgg tgtttctgtt tccagcatta
      181 ttaaaccttt ggcttatcaa gaaaacctct tataaaatag cattcgtaat ttttagtgca
      241 gttttcttat ttctgctatt aggaacgctg tctcgtggtg catggctggc agtattcata
      301 gtgactctgc tatggttaat cttaaatcgt cagtggaaat tattgatgct gacttccatc
      361 gttatttctg ttgccgcagt gggtgtattt acctataaag gtgatcatgc tggtaaagac
      421 aggcttattt ataaacttca acagaccgac agttcttctc gctataccaa tggtactcaa
      481 ggtacggcgt ggacattaat tatggaaaat cctcttaagg gatatggcta cggcgatgat
      541 atttaccatg caatatataa taagcgtgtt gtagattttc cgtcatggaa gttcaggcaa
      601 tccattgggc cacacaacgt tgttttgtca atttggtttg cagcgggttt ggctggacta
      661 ctcgctttac tttatctgta tggctctatt atcaaagaga cagctaatgc aacgtttaaa
      721 acagttgtcg tcactcctta taatggtcaa ttactactat ttttaacgct tgtaagcttt
      781 tatattattc gaggtaactt cgaggaagtt gatctcaaac caattggctt gattgttggt
      841 ttactgttag caatgcggaa taaataaaaa aaagcctgcc tgacattaag ttcaggcagg
      901 ctcttcaaat ccaataattt ttaaccaaac cagtcttgta tttgtgcttc aaaacgctga
      961 gtaacatgtt cccagctata ttttgagaaa acaaaatttc gggcattttt agcaatttga
     1021 gctctgtcag catccgccaa aacgcgctta atatccgcga gaatactttc agatgtcata
     1081 ggctctgcaa ggtgatagcc tgtaattcct tccagaacaa actcactaat tccacctttt
     1141 tgactggcaa gcactggttt acctgccgcc atcgcttcaa cagctaccat acaaaaagct
     1201 tcttctacct gagaaggaac aacaactaaa tctgctaaac ggtaatagtt atgcatctgc
     1261 tctggaggct gtccacccgc cataatgcat tgcgctccaa tagctttcgc tgcatccaga
     1321 acttttttct gatattcagc tttttcgcct tttttactgg caaaaggatc tccgacaatc
     1381 accagtttga ggttatcttg tatcttattc agctgattaa aagcctccat aagcatcagg
     1441 caacctttat ctggtgatat ccttcctgca aataataaca cggtatcatt tgcatcaatg
     1501 ttcagtttct gcctcaaatc ttcagtatta ttttgttcat acgattcaga acaaaaacca
     1561 ttaggcacaa tagcaatatt tgcatcaggc attttttccg aatagaaatc gaaaagaaac
     1621 tggctaggaa caattatctt tgcatttttg tctaactcac ctggctcgaa agcattatga
     1681 agatgcataa ctagctgcgc gtgagggctt ctgctacgaa tctgtttata cagcttcatg
     1741 ctattgtgga taacaataac agagtctttc ggatcagtgt ttttaggttg ggtatttaaa
     1801 atacgctgag aatatggcac aggatcaagt cgagtccact tttggaaaag tcgtttatag
     1861 actcgactaa aaccaatgta gtgaatatca cagtgatcat ttacttttgt gtaggttggg
     1921 taaccttcgt ttcgaataca ggcgatagtt actggaatcg aaagtctttt tgcgacctga
     1981 taaatccatg tttcaaccgc tgcagctcct tttggcggta tagaaaatat tggtgtgacg
     2041 gtaaatatta
//
LOCUS       DAPOAV010000244         2043 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.252, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000244 DAPOAV010000000
VERSION     DAPOAV010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2043
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.252"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..394
                     /locus_tag="RN951_004632"
     CDS             <1..394
                     /locus_tag="RN951_004632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
                     /protein_id="HDX2529491.1"
                     /translation="VSFMKGLFRIVDMKRWYLCPQVRVADIVQLNGNIRPRSRQWWQL
                     FRMVSQWHVDVVIVERRSFSIVAAVELDDASHLRPERRRRDILLEEVLRQAGIPLLRS
                     HDARKLLQMTGEWLNTTGADQQSPEHRS"
     gene            634..888
                     /gene="repA"
                     /locus_tag="RN951_004633"
     CDS             634..888
                     /gene="repA"
                     /locus_tag="RN951_004633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication regulatory protein RepA"
                     /protein_id="HDX2529492.1"
                     /translation="MSQTENAVTSSSGAKRAYRKGNPLSDAEKQRLSVARKRASFKEV
                     KVFLEPKYKAMLMQMCHEDGLTQAEVLTALIKSEAQKRCM"
     gene            1126..1200
                     /gene="tap"
                     /locus_tag="RN951_004634"
     CDS             1126..1200
                     /gene="tap"
                     /locus_tag="RN951_004634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001370046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA leader peptide Tap"
                     /protein_id="HDX2529493.1"
                     /translation="MPGKVQDFFLCSLLLRIVSAGWCD"
     gene            1193..>2043
                     /gene="repA"
                     /locus_tag="RN951_004635"
     CDS             1193..>2043
                     /gene="repA"
                     /locus_tag="RN951_004635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="incFII family plasmid replication initiator
                     RepA"
                     /protein_id="HDX2529494.1"
                     /translation="MTDLHQTYYRQVKNPNPVFTPREGAGTLKFCEKLMEKAVGFTSR
                     FDFAIHVAHARSRGLRRRMPPVLRRRAIDALLQGLCFHYDPLANRVQCSITTLAIECG
                     LATESAAGKLSITRATRALTFLSELGLITYQTEYDPLIGCYIPTDITFTSALFAALDV
                     SEEAVAAARRSRVVWENKQRKKQGLDTLGMDELIAKAWRFVRERFRSYQTELKSRGIK
                     RARARRDANRERQDIVTLVKRQLTREISEGRFTANGEAVKREVERRVKERMILSRNRN
                     YSRLATAS"
BASE COUNT          517 a          490 c          559 g          477 t
ORIGIN      
        1 agtcagtttt atgaaaggac tgttcagaat tgtggatatg aagcggtggt atctgtgtcc
       61 gcaggtacgg gtcgcggata tcgtccagct gaacgggaat atccggccac gatcacgcca
      121 gtggtggcag ttattcagga tggtgtctca gtggcatgtt gatgtggtta tcgttgagcg
      181 gcgttcgttc agtattgttg cagcagtaga gctggatgat gccagccatt tacgaccgga
      241 acgcagacgc cgggatattc ttctggaaga ggttctgagg caggctggta ttccgttgct
      301 cagaagccac gatgccagaa aactgctgca gatgaccgga gaatggctga atacaacagg
      361 ggctgatcag cagtccccgg aacatcgtag ctgacgcctt cgcgttgctc agttgtccaa
      421 ccccggaaac gggaaaaagc aagttttccc cgctcccggc gtttcaataa ctgaaaacca
      481 tactatttca cagtttaaat cacattaaac gacagtaatc cccgttgatt tgtgcgccaa
      541 cacagatctt cgtcacaatt ctcaagtcgc tgatttcaaa aaactgtagt atcctctgcg
      601 aaacgatccc tgtttgagta ttgaggaggc gagatgtcgc agacagaaaa tgcagtgact
      661 tcctcatctg gcgcaaaacg agcatacaga aaggggaatc cgctttctga tgcagagaaa
      721 caaagattat cagtggcccg taaaagagct tcgttcaagg aagtaaaagt atttcttgaa
      781 ccaaagtata aggccatgct catgcaaatg tgtcatgaag atggtctgac tcaggctgaa
      841 gttctgaccg cactgataaa aagtgaagcg caaaaacgat gcatgtgatg atgggcttac
      901 attcttgagt gttcagaaga ttagtgctag attactgatc gtttaaggaa ttttgtggct
      961 ggccacgccg taaggtggca aggaactggt tctgatgtgg atttacagga gccagaaaag
     1021 caaaaacccc gataatcttc ttcaactttg gcgagtacga aaagattacc ggggcccact
     1081 taaaccgtat agccaacaat tcagctatgc ggggagtata gttatatgcc cggaaaagtt
     1141 caagacttct ttctgtgctc gctccttctg cgcattgtaa gtgcaggatg gtgtgactga
     1201 tcttcaccaa acgtattacc gccaggtaaa gaacccgaat ccggtgttta caccccgtga
     1261 aggtgcagga acgctgaagt tctgcgaaaa actgatggaa aaggcggtgg gcttcacttc
     1321 ccgttttgat ttcgccattc atgtggcgca tgcccgttcg cgtggtctgc gtcgacgcat
     1381 gccaccagtg ctgcgtcgac gggctattga tgcgctcctg caggggctgt gtttccacta
     1441 tgacccgctg gccaaccgcg tccagtgctc catcaccacg ctggccattg agtgcggact
     1501 ggcgacggag tctgctgccg gaaaactctc catcacccgt gccacccggg ccctgacgtt
     1561 cctgtcagag ctgggactga ttacctacca gacggaatat gacccgctta tcgggtgcta
     1621 cattccgacc gatatcacgt tcacatctgc actgtttgct gccctcgatg tatcagagga
     1681 ggcagtggcc gccgcgcgcc gcagccgtgt ggtatgggaa aacaaacaac gcaaaaagca
     1741 ggggctggat accctgggca tggatgaact gatagcgaaa gcctggcgtt ttgtgcgtga
     1801 gcgtttccgc agttaccaga cagagcttaa gtcccgtgga ataaaacgtg cccgtgcgcg
     1861 tcgtgatgcg aacagagaac gtcaggatat cgtcaccctg gtgaaacggc agctgacgcg
     1921 tgaaatctcg gaaggacgct tcactgctaa tggtgaggcg gtaaaacgcg aagtggagcg
     1981 tcgtgtgaag gagcgcatga ttctgtcacg taaccgcaat tacagccggc tggccacagc
     2041 ttc
//
LOCUS       DAPOAV010000245         2040 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.253, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000245 DAPOAV010000000
VERSION     DAPOAV010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2040
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.253"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..995
                     /gene="galE"
                     /locus_tag="RN951_004636"
     CDS             <1..995
                     /gene="galE"
                     /locus_tag="RN951_004636"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000154261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HDX2529495.1"
                     /translation="AGYIGSHTVLQLIEGGYDVVVLDNLSNSSQESLHRVGSLVSKKI
                     PFIEADINDKQKLEEVFKNYDIDAVIHFAGLKSVGESVKKPLEYYINNVSGTLTLLEV
                     MKQASVYKFIFSSSATVYGNHSPVPNLEEYPIGNASCPYGTTKVMLEQVLSDYAKSDD
                     KLKIIALRYFNPTGAHPSGLIGEDPNGIPNNLVPYISQVAIGKLEKLSVYGGDYETID
                     GTGVRDFIHVVDLASGHVSALRHIDKLQGYDVFNLGTGNGVSVLQVIDAFEKASDKKV
                     NYEIVARREGDIGSSWADVSKAERVLGWKAKYNIEDMMAHTWNWQKQNPNGYGS"
     gene            1029..>2040
                     /locus_tag="RN951_004637"
     CDS             1029..>2040
                     /locus_tag="RN951_004637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDX2529496.1"
                     /translation="MNLFFIVDKLDWAFGKIAQNIAKELSDFNVKIVCTDDFKTVADL
                     VLHLDKNVKEKSILHFFWRDYLMEVMNFTQRNPQYKEILISNIVTTHIPDHLFTYDDI
                     ANYERRIPLMNFVDGYFVTSAKLKELYSELSDFPPPHSVIYDNPEIPMSEGNSHDNSD
                     RKKLVWIGNSKWGEYLGYKDYKGLNKIVLPALDKLKKSGYTFDFIEFDSSKGKTEREV
                     ILKTLSDADILLISSECEGTPLPLLEAMANSCAIVSTDVGIANEVLPEKQRQYIVSRD
                     AEAFYDSLRNLLDDQRGLKELQRMNYLAYRQQFVDDGLIADKWALFFKDMCSKSQNEF
                     KNI"
BASE COUNT          640 a          333 c          432 g          635 t
ORIGIN      
        1 gcgctggtta tattggttca cataccgttt tacagttaat tgagggcgga tatgatgtgg
       61 ttgtgcttga taacctgagt aattcatctc aagagtcact tcatcgtgtt ggttctttgg
      121 tttcgaaaaa aattccattc attgaagctg atatcaacga taaacaaaaa cttgaagaag
      181 tttttaaaaa ctacgatatc gatgcagtga ttcattttgc aggattaaaa tctgtgggtg
      241 aatcggtaaa aaaaccgctg gaatattata ttaataatgt cagtgggacc ctcaccctgc
      301 ttgaagttat gaagcaagca agtgtttata agttcatttt tagttcgtcc gcaactgttt
      361 atggtaacca ttctccggtt cccaacctgg aggaatatcc tattggaaat gcttcctgcc
      421 cctatggtac tactaaagtc atgctggagc aggttttatc agactacgcg aaatctgatg
      481 ataaattgaa gattattgct cttcgttatt ttaaccctac aggcgcacat cctagtggtc
      541 ttattgggga ggacccgaac ggcattccaa ataatcttgt cccttatatt tctcaggttg
      601 ctattggaaa attagaaaaa ttgtccgttt atggtggcga ttatgaaacc attgatggaa
      661 caggggtacg cgactttatc catgtagtag atcttgcctc aggccatgtt agtgctttaa
      721 ggcatattga taaattacaa ggatatgacg tttttaatct tggcaccggc aatggtgtat
      781 cagttttaca agtaattgat gcctttgaaa aggcaagtga caagaaagtt aactatgaaa
      841 ttgtcgccag gcgagagggc gatataggat cttcttgggc tgatgtctct aaagcagaaa
      901 gggttttagg ctggaaagcc aagtacaata ttgaagatat gatggctcat acctggaatt
      961 ggcaaaagca aaaccctaat ggctatggaa gctagtactt atctatttaa tatcataatg
     1021 gcgtatcaat gaatttattt ttcatagtcg ataagttgga ttgggcattc ggaaaaatag
     1081 cccaaaatat agcaaaagag ttgagtgact ttaatgtaaa aatagtttgc accgatgatt
     1141 ttaaaacggt ggcggacctt gttttacact tggataaaaa cgtaaaagaa aagagtatct
     1201 tacacttttt ctggcgtgac tatctcatgg aagtgatgaa cttcactcag cggaatcccc
     1261 agtataaaga aattttgatc agcaatattg tcaccacaca tattcctgat cacctattca
     1321 cttatgatga tatcgcgaac tatgagagac gaattcctct tatgaatttt gtggatgggt
     1381 attttgttac atccgcaaag ttgaaagagc tatattctga actgtctgat tttccacctc
     1441 ctcatagtgt tatctatgat aatccagaaa ttcctatgag cgaaggaaat agtcatgata
     1501 atagcgatag aaaaaaactc gtatggattg gaaatagcaa atggggcgaa tatcttggtt
     1561 ataaagatta taaaggcctg aataaaatag ttttgccggc tctggataaa ttaaaaaaat
     1621 ctggatatac gtttgatttt attgagtttg atagttctaa gggcaagacc gaacgtgaag
     1681 taattcttaa aacactgtct gatgcagata ttctactcat cagttctgaa tgtgaaggta
     1741 cgccattgcc acttcttgaa gcaatggcaa acagttgcgc tattgtgtca acagacgtcg
     1801 gcatagcaaa tgaagtgtta cctgaaaagc agcggcagta tattgtgtct cgggatgccg
     1861 aggcatttta tgattctttg agaaatcttc ttgatgatca acgtggtctt aaagaattac
     1921 aaagaatgaa ttatttagca tatcgtcagc aatttgtaga tgatggcctt atagctgata
     1981 aatgggcatt gttcttcaaa gacatgtgtt caaaatcgca aaatgaattt aagaatatat
//
LOCUS       DAPOAV010000246         2011 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.254, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000246 DAPOAV010000000
VERSION     DAPOAV010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2011
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.254"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(171..1064)
                     /gene="galF"
                     /locus_tag="RN951_004638"
     CDS             complement(171..1064)
                     /gene="galF"
                     /locus_tag="RN951_004638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GalU regulator GalF"
                     /protein_id="HDX2529497.1"
                     /translation="MINLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEIVLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNV
                     RQAQLLGLGHSILCARPIVGDNPFVVVLPDVVLDTASADPLRYNLAAMVARFNETGRS
                     QVLAKRMEGDLSEYSVIQTKEPLDNEGKVSRIVEFIEKPDQPQTLDSDLMAVGRYVLS
                     ADIWAELEHTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKY
                     GLRNLKEGPKFRKSIEKLLGE"
     gene            complement(1229..>2011)
                     /gene="wcaM"
                     /locus_tag="RN951_004639"
     CDS             complement(1229..>2011)
                     /gene="wcaM"
                     /locus_tag="RN951_004639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785186.1"
                     /note="WcaM from Salmonella enterica is essential for
                     biofilm formation on HEp-2 cells and chicken intestinal
                     tissue but not on a plastic surface; may be involved in
                     the biosynthesis of colanic acid; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis protein WcaM"
                     /protein_id="HDX2529498.1"
                     /translation="ILISDHVIERINCTNGNVNWGIGIGLAGSTYDNTYPDELAVKNF
                     VVANITGSDCRQLVHVENGKHFIIRNITARNITPDYSKKAGIDNATVAIYGCDNFVID
                     NINMENSAGMLIGYGVIKGRYLSIPQNFKLNNIHLDNTKREYKLRGIQISSGNATSFV
                     AITNVEMKRATLELHNQPQHLFLRNIRVMQQSATGPALKMHFDLRQDVRGKFMAKQDT
                     LLSLANVHAVNESGQSSVDIDRVNHQVVNVEAVNFRLPGRER"
BASE COUNT          519 a          504 c          425 g          563 t
ORIGIN      
        1 aagaagaaat cgatttttgc tacaagaaaa ggtagagcat tgatcttttt actacttgat
       61 ttttatcata aaaaaggcag tgaagacatg cctgtatact gatagcatca tgagtcttcc
      121 cctgccattt atcatgaagt attactaata taattaatct ttcgtcttgc ctattctccg
      181 agcaacttct caatgctctt acggaacttc ggcccttctt tcaggttacg caggccgtac
      241 ttaacaaacg cctgcatata ccccattttc ttcccgcagt cgtagctgtc gcccgtcatc
      301 agcatcgcat ctaccgactg ttttttagcc agctcagcaa tagcatccgt caattgaata
      361 cgcccccagg caccaggctg ggtatgctcc agttctgccc agatatccgc agaaagcacg
      421 tagcgcccta ctgccatcag atcggaatcc agagtctgcg gctggtctgg tttttcaatg
      481 aattcaacga tacggctgac tttaccttcg ttatctaaag gctctttggt ctgaataaca
      541 gagtactcag acagatcgcc ttccatacgc ttagccagca cctgactacg cccggtttca
      601 ttaaaacgag caaccatggc agccaggttg tagcgcagcg gatctgcgct cgctgtatca
      661 agaaccacat caggtaatac gactacgaaa gggttatccc caacaattgg acgagcacaa
      721 agaattgaat gacccaggcc cagtaactga gcctgacgaa cgttcataat agtcacgcct
      781 ggaggacaga tagactgcac ctcggctaat agctggcgtt taacacgctg ctcaagcaac
      841 gattcgagtt cgtaagaggt gtcgaagtgg ttctcaaccg cgttcttaga cgcatgagtc
      901 accagcacga tttctttgat acctgcagct acaatttcgt cgacaatgta ttgaatcatc
      961 ggcttgtcta cgatcggtag catctcttta gggattgcct tcgtggcagg caacatgtgc
     1021 atccccagac ctgctaccgg aataactgct ttcaaattaa tcattaagtc attcacctat
     1081 tcaattgttg ctgaattata gctttttagc ttgttttagc cagtatgaat tacattactc
     1141 cgatgcagcg tatgttacgc cgcttaactt cgcaatgcag taatcttaat cccagggagt
     1201 gtcactttag ccaggaatgg tcgcaaagtt accgctcccg tcccgggagt cgaaaattca
     1261 ccgcttcgac attcaccacc tgatggttta cccggtcgat gtcaactgag ctttgcccgc
     1321 tttcgtttac cgcatggaca ttcgccagcg agagtaatgt gtcctgtttt gccataaact
     1381 tgccgcgcac atcctgacgg agatcgaagt gcatcttaag cgcgggtccc gtcgcggatt
     1441 gctgcataac cctgatgtta cgtaaaaaaa ggtgctgtgg ttggttatgc aactcaagcg
     1501 tggcacgttt catctccaca ttggtaatcg ccacaaatga tgtcgcatta ccagaggaga
     1561 tctgaatacc gcgcaatttg tattcacgtt tcgtattatc cagatggata ttatttaact
     1621 taaagttttg tggaatggat aaataacgcc ctttgattac gccgtaacca atgagcatac
     1681 ctgcgctatt ctccatattg atattatcaa ttacgaaatt atcacatccg taaatagcga
     1741 ccgtcgcatt atcaatgccc gctttcttac tataatccgg ggtgatattt cgcgcggtaa
     1801 tattacgaat aataaagtgt ttgccgttct ccacatggac taactgtcgg cagtcgctac
     1861 cggtgatgtt cgctaccaca aagtttttta ccgccagttc atcgggatag gtattgtcat
     1921 aggtactccc cgccagaccg atgccgatgc cccagttcac gttgccgttg gtacagttga
     1981 tacgttcaat gacatggtca gaaatgagga t
//
LOCUS       DAPOAV010000247         2004 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.255, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000247 DAPOAV010000000
VERSION     DAPOAV010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2004
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.255"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            1..866
                     /locus_tag="RN951_004640"
                     /pseudo
     CDS             1..866
                     /locus_tag="RN951_004640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            952..1974
                     /gene="istA"
                     /locus_tag="RN951_004641"
     CDS             952..1974
                     /gene="istA"
                     /locus_tag="RN951_004641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element IS100 family transposase"
                     /protein_id="HDX2529499.1"
                     /translation="MVTFETVMEIKILHKQGMSSRAIARELGISRNTVKRYLQAKSEP
                     PKYTPRPAVASLLDEYRDYIRQRIADAHPYKIPATVIAREIRDQGYRGGMTILRGFIR
                     SLSVPQEQEPAVRFETEPGRQMQVDWGTMRNGRSPLHVFVAVLGYSRMLYIEFTDNMR
                     YDTLETCHRNAFRFFGGVPREVLYDNMKTVVLQRDAYQTGQHRFHPSLWQFGKEMGFS
                     PRLCRPFRAQTKGKVERMVQYTRNSFYIPLMTRLRPMGITVDVETANRHGLRWLHDVA
                     NQRKHETIQARPCDRWLEEQQSMLALPPEKKEYDVHPGENLVNFDKHPLHHPLSIYDS
                     FCRGVA"
BASE COUNT          460 a          550 c          571 g          423 t
ORIGIN      
        1 ggaaaagctg aacgagcgtg aacgcgaaat agaccatctg caggcgcagc tggataaact
       61 ccgccggatg aacttcggca gtcgttccga aaaagtctcc cgccgtatcg cacaaatgga
      121 agccgatctg aaccggcttc agaaagagag cgatagagag cgatacgctg actggtaggg
      181 tgtatgaccc ggcagtacag cgtccgttgc gtcagacccg cacccgtaag ccgttccctg
      241 aatcactacc ccgtgacgaa aagcggctgt tgcctgcggc gccgtgctgc ccgaactgcg
      301 gcggttcact gagctatctg ggcgaggata ccgccgaaca gctggagttg atgcgtagcg
      361 ccttccgggt tatccggacg gtacgggaaa aacatgcctg tactcagtgc gatgccatcg
      421 tgcaggcacc tgcaccttcg cggcccatcg agcggggtat cgccggaccg gggctgctgg
      481 cccgcgtgct gacctcgaag tatgcagagc acaccccgct gtatcgccag tcagaaatat
      541 acggccggca aggtgtggag ctgagccgtt cactgctgtc gggctgggtg gatgcatgct
      601 gccggctgct gtctccgctg gaagaggcgc ttcatggcta tgtgctgact gacggtaagc
      661 tccatgctga tgacacgcct gtcccggtgc tgttgccagg caataagaaa acgaagaccg
      721 ggcggttatg gacctacgtt cgtgacgacc gtaacgccgg gtcaacgctg gcgccggcgg
      781 tgtggttcgc ttacagcccg gacagaaaag gcatccatcc gcagacccat cttgcggggt
      841 tcagtggtgt actgcaggcg gatgctgtca cgaacggtgc aatagtgatc cacacccaac
      901 gcctgaaatc agatccaggg ggtaatctgc tctcctgatt caggagagtt tatggtcact
      961 tttgagacag ttatggaaat taaaatcctg cacaagcagg gaatgagtag ccgggcgatt
     1021 gccagagaac tggggatctc ccgcaatacc gttaaacgtt atttgcaggc aaaatctgag
     1081 ccgccaaaat atacgccgcg acctgctgtt gcttcactcc tggatgaata ccgggattat
     1141 attcgtcaac gcatcgccga tgctcatcct tacaaaatcc cggcaacggt aatcgctcgc
     1201 gagatcagag accagggata tcgtggcgga atgaccattc tcaggggatt cattcgttct
     1261 ctctcggttc ctcaggagca ggagcctgcc gttcggttcg aaactgaacc cggacgacag
     1321 atgcaggttg actggggcac tatgcgtaat ggccgctcac cgcttcacgt gttcgttgct
     1381 gttctcggat acagccgaat gttgtacatc gaattcactg acaatatgcg ttatgacacg
     1441 ctggagacct gccatcgtaa tgcgttccgc ttctttggtg gtgtgccgcg cgaagtgttg
     1501 tatgacaata tgaaaactgt ggttctgcaa cgtgacgcat atcagaccgg tcagcaccgg
     1561 ttccatcctt cgctgtggca gttcggcaag gagatgggct tctctccccg actgtgtcgc
     1621 cccttcaggg cacagactaa aggtaaggtg gaacggatgg tgcagtacac ccgtaacagt
     1681 ttttacattc cactaatgac tcgcctgcgc ccgatgggga tcactgtcga tgttgaaaca
     1741 gccaaccgcc acggtctgcg ctggctgcac gatgtcgcta accaacgaaa gcatgaaaca
     1801 atccaggccc gtccctgcga tcgctggctc gaagagcagc agtccatgct ggcactgcct
     1861 ccggagaaaa aagagtatga cgtgcatcct ggtgaaaatc tggtgaactt cgacaaacac
     1921 cccctgcatc atccactctc catctacgac tcattctgca gaggagtggc gtgatgatgg
     1981 aactgcaaca tcaacgactg atgg
//
LOCUS       DAPOAV010000248         1963 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.256, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000248 DAPOAV010000000
VERSION     DAPOAV010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1963
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.256"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..>1963
                     /gene="rhsB"
                     /locus_tag="RN951_004642"
     CDS             <1..>1963
                     /gene="rhsB"
                     /locus_tag="RN951_004642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="rhs element protein RhsB"
                     /protein_id="HDX2529500.1"
                     /translation="RPEIRYRYDSDGRVTEQLNPAGLSYTYQYEKDHITITDSLNRRE
                     VLHTQGEAGLKRVVKKEHADGSVTQSQFDAVGRLRTQTDAAGRTTEYSPDVVTGLITR
                     ITTPDGRASAFYYNHHSQLTSATGPDGLEIRREYDELGRLIQETAPDGDITRYRYDNP
                     HSDLPCATEDATGSRKTMTWSRYGQLLSFTDCSGYVTRYDHDRFGQMTAVHREEGLSQ
                     YRAYDSRGQLIAVKDTQGHETRYEYNAAGDLTAVIAPDGSRNGTQYDAWGKAICTTQG
                     GLTRSMEYDAAGRVIRLTSENGSHTTFRYDVLDRLIQETGFDGRTQRYHHDLTGKLIR
                     SEDEGLVTHWHYDEADRLTHRTVNGETAERWQYDERGWLTDISHISEGHRVAVYYGYD
                     EKGRLTGERQTVHHPETEALLWQHETRHAYNAQGLANRCIPDSLPAVEWLAYGSGYLA
                     GMKLGDTPLVDFTRDRLHRETLRSFGRYELTTAYTPAGQLQSQHLNSLLSDRDYTWND
                     NGELIRISSPRQTRSYSYSTTGRLTGVHTTAANLDIRIPYATDPAGNRLPDPELHPDS
                     TLSMWPDNRIARDAHYLYRYDRYGRLTEKTDLIPEGGIRTDDERTHRYHYDSQHRLVH
                     YTRTQYAEPLVESRYLYDPLGRRVAKRVWR"
BASE COUNT          476 a          608 c          583 g          296 t
ORIGIN      
        1 gccgaccgga aatccgttac cgttacgaca gcgacgggcg ggtgacagaa cagctaaacc
       61 cggcaggctt aagctacacg tatcagtatg agaaagacca catcaccatc accgacagcc
      121 tgaaccgccg tgaagtgctg cacacgcagg gcgaagccgg gctgaagcgg gtggtgaaaa
      181 aggaacacgc ggacggcagc gtcacgcaga gtcagtttga cgccgtgggc aggctcagga
      241 cacagacgga tgccgcaggc cggacaacag aatacagccc ggatgtggtg acgggcctca
      301 tcacgcgcat caccacgccg gatggcaggg catcggcgtt ttactataac caccacagcc
      361 agttaacgtc agccaccggg cctgacgggc tggaaatacg ccgggaatat gatgaattgg
      421 gccgtctgat tcaggaaact gcccctgacg gcgatatcac ccgctaccgt tatgataatc
      481 cacacagtga cttaccctgc gcaacggaag atgccaccgg cagccggaaa accatgacgt
      541 ggagccgtta cggtcagttg ctgagcttca ccgactgttc cggttatgta acccgttatg
      601 accatgaccg cttcgggcag atgacggcgg tgcaccgcga ggaagggctg agtcagtacc
      661 gcgcatacga cagccgtgga cagttaattg ccgtgaaaga cacgcagggc catgaaacgc
      721 ggtatgaata caacgccgcc ggtgacctga ccgccgtcat tgccccggac ggcagcagaa
      781 acgggacaca gtacgatgcg tggggaaaag ccatctgtac cacgcagggc ggtctgacgc
      841 gcagtatgga atacgatgct gccggacggg tcatccgcct gaccagtgaa aacggcagcc
      901 acaccacctt ccgttacgat gtactcgacc ggctgataca ggaaaccggc tttgacggcc
      961 gcacacagcg ttatcaccac gacctgaccg gcaaacttat ccgcagcgag gatgaggggc
     1021 tggtcaccca ctggcactat gacgaagcag accgcctcac gcaccgcacc gtgaatggcg
     1081 aaaccgcaga gcggtggcag tatgacgaac gcggctggct gacagacatc agccatatca
     1141 gcgaagggca ccgggtggcg gtgtattatg gatatgatga gaaaggccgc ctgaccggtg
     1201 agcgccagac ggtgcatcac ccggagacgg aagcactgct ctggcagcat gagaccagac
     1261 atgcgtacaa cgcgcaggga ctggcgaacc gctgtatacc ggacagcctg cccgccgtgg
     1321 aatggctggc ctacggcagc ggttacctgg caggcatgaa gctcggcgac acaccgctgg
     1381 tggatttcac ccgcgaccgc ctgcaccggg aaacgctgcg cagcttcggc cgttatgaac
     1441 tcaccaccgc ttacacccct gccgggcagt tacagagcca gcacctgaac agcctgctgt
     1501 ctgaccgcga ttacacctgg aacgacaacg gcgaactcat ccgcatcagc agcccgcgcc
     1561 agacccggag ttacagctac agcaccaccg gcaggctgac cggcgttcac accaccgcag
     1621 cgaatctgga tatccgcatc ccgtatgcca cagacccggc aggtaaccgc ctgcccgacc
     1681 cggagctgca cccggacagc accctcagca tgtggccgga taaccgtatc gcccgtgacg
     1741 cgcactatct ttaccggtat gaccgttacg gcaggctgac ggagaaaacc gacctcatcc
     1801 cggaaggggg tatccgtacg gatgatgagc gcacccaccg gtaccattac gacagtcagc
     1861 accggctggt gcactacacg cggacacaat atgcagagcc gctggtcgaa agtcgctatc
     1921 tttacgaccc gctgggccgc agggtggcaa aacgggtatg gcg
//
LOCUS       DAPOAV010000249         1946 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.257, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000249 DAPOAV010000000
VERSION     DAPOAV010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1946
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.257"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            565..822
                     /locus_tag="RN951_004643"
     CDS             565..822
                     /locus_tag="RN951_004643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001333498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX2529501.1"
                     /translation="MEMEKQDWHKADIIAALHKKGLSLASLSRANGLSSSTLANALTR
                     DWPRGEIIIANAIGEEPQEIWPTRYFDKAGMPIKRIIRKPV"
     gene            993..1484
                     /locus_tag="RN951_004644"
     CDS             993..1484
                     /locus_tag="RN951_004644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000217395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDX2529502.1"
                     /translation="MTVLSAPEMRFGTKQDVPFIIAVIRDGMRDGYFNFDDDDGLSQF
                     ESQISEAIARRERGENCADFLFVFDAQHNGAAIGFALLTGKNGANGLASHLEIRMFGV
                     TRSQRQKGFGRSMLQSILDATPGHKVEASCLPASVVMARMLTNAGFHVKEISPFGKRT
                     FRR"
     gene            complement(1570..1932)
                     /locus_tag="RN951_004645"
     CDS             complement(1570..1932)
                     /locus_tag="RN951_004645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529503.1"
                     /translation="MVYFIPDTAVDPIEPVAYKIRFSFSNPDLLLKSAIEKYGEPSVS
                     DAQRGRYIWCKALAEKTNKCDDSKSELTLTTREVEDTGILTLSDPTVSFDASRTATAT
                     PDKDQAATEDNQGPLPQL"
BASE COUNT          513 a          449 c          485 g          499 t
ORIGIN      
        1 cctgcccatg aactcccgga ttatatccac tatcacctgg aacgggccgg agtgatctgt
       61 ggacggttac gtatcgttcg aagcaccaag ttccatatta ttaagcccgg gagcgttggc
      121 cgtacatccc acaagatcat tgtaccgatg agccagtacg atgctgaatg cgtgattgaa
      181 gatgtcggcg cacttgaaca ggcatacgct ttcgggatcg gcagaaagcg gatattcggc
      241 tttggctata tgaacagcat cgaagtgctt tcctgaacag gccattaagc atagttatta
      301 tctgaatttc aaaccgactc gcaaacttac ggcattaaca cttctgatac accctttaaa
      361 tgctgtaaac tgttgtagcc cttactaaat cgtaagagtg gggatttgca gccccgacta
      421 atgacacgcc gttcatgtac ttgaacggtt cgcactcgct cgcctgtttt ttgtcaatgg
      481 tgggtcgggg cgtgggagcc ttacggctcg ccagtcgtca ttagctggta ctgcaaacca
      541 tgttccgatt caccaccaaa ggaaatggag atggaaaaac aggactggca taaggcagac
      601 atcatagctg cgctacataa gaaaggtttg tcacttgcct cactgagtag ggctaacggt
      661 ctttcaagca gcactctggc aaatgcactg acacgtgact ggcctagagg cgagatcatc
      721 atcgctaatg caattggtga agaacctcaa gaaatatggc caacccgata ttttgataag
      781 gcaggaatgc cgatcaagag aatcataaga aaaccggttt aaatgaaaaa ggctggcatt
      841 tttgctggcc ttatatacct cctggctctg ctactgaaac cactaacacc gatcaaatgg
      901 tcatcagcga aataccccgt tcatttctat tgacctcttt acctccatgt aatcaaattg
      961 atggaataat aacggttacg agagacaaac tgatgacggt gttatctgcc cctgaaatgc
     1021 gctttggaac caaacaggat gttcccttta tcatagcggt gattcgcgac ggtatgcggg
     1081 atgggtattt taactttgat gatgatgacg gactgtctca gttcgaaagt cagatctcag
     1141 aagccattgc caggcgggaa cggggagaga attgcgccga tttcttgttt gtctttgatg
     1201 ctcaacataa tggcgcagcg ataggttttg ccctactgac gggcaaaaat ggtgcaaatg
     1261 gacttgcttc acatctggaa atcaggatgt ttggtgttac caggagtcaa agacaaaaag
     1321 gatttgggcg ctccatgttg caaagtattc tggatgctac tcccggccat aaagtggagg
     1381 catcctgtct tcctgcatca gttgtcatgg ccaggatgct gactaatgcg ggttttcacg
     1441 tcaaagagat aagcccgttt ggaaagcgta ctttcagacg ctaatgtaaa attcagataa
     1501 aaaaaccggc tgacgaattc agtcggttta gtaatcctgc aaaaggatgc tggacagcga
     1561 cggacgactt cagagctgtg gcaatggccc ctggttatct tcagtcgcag cctggtcttt
     1621 atccggggtg gccgttgcag tccgcgaggc atcaaatgag accgttgggt cgctgagagt
     1681 caggatgcca gtgtcttcaa cttctcgcgt tgtcagcgta agctcagatt tactgtcatc
     1741 acacttattc gttttctccg ccagtgcctt gcaccagata taacgacctc tctgggcatc
     1801 agagactgaa ggctctccat atttctcgat cgccgacttc agtaagagat cagggttgct
     1861 gaatgaaaag cggattttgt aagccaccgg ctcaatgggg tcaactgccg tatcggggat
     1921 aaaatagacc accgtctcct ggtgag
//
LOCUS       DAPOAV010000250         1842 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.258, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000250 DAPOAV010000000
VERSION     DAPOAV010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1842
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.258"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            712..1629
                     /locus_tag="RN951_004646"
     CDS             712..1629
                     /locus_tag="RN951_004646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016230784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529504.1"
                     /translation="MVQKILSDKVMNERTNAYYSYYLGERNISVLPLNVYDPPERFIA
                     YIKKNRENLNITLSDFELEQIISGMRLKALASLVPLEKISWIAGSERACLFSWYLLMQ
                     FIQNNRTKISADLLQKNKLYLKEEYLEGNAFPSDSSTQFRQILRVLDILSDKNLRDEW
                     IIQTKDRWIRAFKSKSPFSYLLPENEHECIWTWNYLKGKNIALEKLASFPDSADIYHA
                     IHLSFDIWVTCPLTSPDDIKNFRNSFNKAKAQRKYKKMQEDKVNVQFFLDAETRAQLK
                     ELSRVRRLSTGEMLHDLIVEEYKRYRHSR"
     gene            1714..>1842
                     /locus_tag="RN951_004647"
     CDS             1714..>1842
                     /locus_tag="RN951_004647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
                     /protein_id="HDX2529505.1"
                     /translation="MNPSDAIEAIEKPLSSLPYSLSRHILEHLRKLTSHEPVIGIMG"
BASE COUNT          524 a          417 c          365 g          536 t
ORIGIN      
        1 tgatgccgga acatatctga aacacgttat gatgttttgt tatcagaaat gttgtatatt
       61 cttatccgtg gcgacagttt aatgccctct ggtatcacct gataatgcat atcctgcgat
      121 gattcgttat atttacggga cacgcctctt ttcattgtgc tccttttcag acttcatttt
      181 ccgtaagtgt tccccggcat aaaggaggta cctttctggc gtttataact ctctttatcg
      241 gtgacgccgg taatacaggg aataccacac cgacaaacga ggtattaaca gacgatattt
      301 cagtgtccat aatttttctg tccggttaaa taacgtcagt ctgctgccct ctgactgtaa
      361 tcatcaaagc cggaatgcat accgggttac aacgtaaaaa aagtgatgct ggcccccggt
      421 gcagctggcg ggcgaaacat gtttaccttt caataccccc tgtctgcagt ctccactctt
      481 ccatcctctt aagctacgtc ggccacatga gtgcacttcc atgataacag gtattcctgt
      541 cagcataacg aagccggtta tcttcccttc ctcctgcatt tcctgtcaga atgactatac
      601 agcgcgcaga ttgccttttt attgaccatc ttaatatacc attatacact tctttttatc
      661 atgttattat caccttatta tgtttaattt ttaagcatcc ggagaaagag gatggttcag
      721 aaaattttgt cggataaggt tatgaatgaa agaacaaatg cgtattactc ttattatctt
      781 ggagagcgta atatctccgt actgcccctt aatgtttatg atcccccgga acgttttatc
      841 gcttacataa aaaaaaacag agaaaatctg aacatcacac tttcagattt tgaacttgaa
      901 caaatcattt ctggtatgcg tctgaaggca ctggcctccc tggtgcccct ggaaaaaata
      961 tcctggatcg cgggcagtga acgcgcatgc ttattttcct ggtatctgtt gatgcagttt
     1021 atccagaata acaggacaaa aataagcgca gacttgcttc aaaagaataa actgtatctt
     1081 aaagaagagt atttagaagg gaatgccttc ccgtcggact catcgacaca gttcagacaa
     1141 atactcagag ttctcgatat tctttctgat aagaatttgc gggatgagtg gataatccag
     1201 accaaagaca gatggatacg ggcatttaaa tcaaagagtc ctttcagtta cctcctcccg
     1261 gagaacgaac atgaatgcat atggacatgg aattatttga agggaaaaaa tattgcactg
     1321 gaaaaactgg ccagttttcc tgattctgct gatatttacc acgcaattca cctttcattt
     1381 gacatatggg ttacctgtcc actcacctca cctgacgata taaaaaattt cagaaacagt
     1441 ttcaataagg ccaaggcgca gcgcaagtac aaaaaaatgc aggaagataa agtcaatgta
     1501 cagttttttc ttgacgcaga aaccagggcg cagctcaaag aattatcgag ggtcagaaga
     1561 ctcagtaccg gcgaaatgct gcatgacctg attgttgaag agtataaaag gtaccgacat
     1621 tccagataat ttcagacata tattatctct gtgagtcccc cgccaccttt ccggtgtgcg
     1681 ggggttttgt cttttttcac cgggaataca tgtatgaatc cgtctgatgc cattgaggca
     1741 attgaaaaac cgctctcctc cctgccttac tcactttccc gtcacatcct ggaacatctg
     1801 cgcaaactca ccagtcacga acccgtgatt ggcattatgg gt
//
LOCUS       DAPOAV010000251         1819 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.259, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000251 DAPOAV010000000
VERSION     DAPOAV010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1819)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1819)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1819
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.259"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            1..596
                     /locus_tag="RN951_004648"
                     /pseudo
     CDS             1..596
                     /locus_tag="RN951_004648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415229.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
     gene            658..>1819
                     /locus_tag="RN951_004649"
     CDS             join(658..919,919..>1819)
                     /locus_tag="RN951_004649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477168.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDX2529506.1"
                     /translation="MTKTVSTSKKPRKQHSPEFRSEALKLAERIGVTAAARELSLYES
                     QLYNWRSKQQNQQTSSERELEMSTEIARLKRQLAERDEELAILPKGRDILREAPEMKY
                     VFIEKHQAEFSIKAMCRVLRVARSGWYTWCQRRTRISTRQQFRQHCDSVVLAAFTRSK
                     QRYGAPRLTDELRAQGYPFNVKTVAASLRRQGLRAKASRKFSPVSYRAHGLPVSENLL
                     EQDFYASGPNQKWAGDITYLRTDEGWLYLAVVIDLWSRAVIGWSMSPRMTAQLACDAL
                     QMALWRRKRPRNVIVHTDRGGQYCSADYQAQLKRHNLRGSMSAKGCCYDNACVESFFH
                     SLKVECIHGEHFISREIMRATVFNYIECDYNRWRRHSWCGGLSPEQFENKNLA"
BASE COUNT          444 a          503 c          528 g          344 t
ORIGIN      
        1 ccacagaccc ggcaggtaac cgcctgcccg acccggagct gcacccggac agcgccctca
       61 gcatgtggcc ggataaccgt atcgcccgtg acgcgcacta tctttaccgg tatgaccgtc
      121 acggcaggct gacagagaaa accgacctca tcccggaagg ggttatccgc acggatgatg
      181 agcgcaccca ccggtaccat tacgacagtc agcaccggct ggtgcactac acgcggacac
      241 aatatgcaga gccgctggtc gaaagtcgct atctttacga cccgctgggc cgcagggtgg
      301 caaaacgggt atggcggcgt gaacgggacc tgacgggctg gatgtcgctg tcacggaaac
      361 cgcaagtgac ctggtacggc tgggacggcg accgcctgac cacgatacag aacgacagaa
      421 cccgcatcca gacgatttat cagccgggga gcttcacgcc actcatcagg gttgaaaccg
      481 ccaccggtga gctggcgaaa acgcagcgcc gcagcctggc ggataccctt cagcagtccg
      541 gcggcgaaga cggtggcagt gtggtgttcc cgccggtgct ggtgcagatg cttgatctta
      601 cccagcaata gtggacacgc ggctaagtga gtaaactctc agtcagaggt gactcacatg
      661 acaaaaacag tatcaaccag taaaaaaccc cgtaaacagc attcgcctga atttcgcagt
      721 gaagccctga agcttgctga acgcatcggt gttactgccg cagcccgtga actcagcctg
      781 tatgaatcac aactctacaa ctggcgcagt aaacagcaaa atcagcagac gtcttctgaa
      841 cgtgaactgg agatgtctac cgagattgca cgtctcaaac gccagctggc agaacgggat
      901 gaagagctgg ctatcctcca aaaggccgcg acatacttcg cgaagcgcct gaaatgaagt
      961 atgtctttat tgaaaaacat caggctgagt tcagcatcaa agcaatgtgc cgcgtgctcc
     1021 gggtggcccg cagcggctgg tatacgtggt gtcagcggcg gacaaggata agcacgcgtc
     1081 agcagttccg ccaacactgc gacagcgttg tcctcgcggc ttttacccgg tcaaaacagc
     1141 gttacggtgc cccacgcctg acggatgaac tgcgtgctca gggttacccc tttaacgtaa
     1201 aaaccgtggc ggcaagcctg cgccgtcagg gactgagggc aaaggcctcc cggaagttca
     1261 gcccggtcag ctaccgcgca cacggcctgc ctgtgtcaga aaatctgttg gagcaggatt
     1321 tttacgccag tggcccgaac cagaagtggg caggagacat cacgtactta cgtacagatg
     1381 aaggctggct gtatctggca gtggtcattg acctgtggtc acgtgccgtt attggctggt
     1441 caatgtcgcc acgcatgacg gcgcaactgg cctgcgatgc cctgcagatg gcgctgtggc
     1501 ggcgtaagag gccccggaac gttatcgttc acacggaccg tggaggccag tactgttcag
     1561 cagattatca ggcgcaactg aagcggcata atctgcgtgg aagtatgagc gcaaaaggtt
     1621 gctgctacga taatgcctgc gtggaaagct tctttcattc gctgaaagtg gaatgtatcc
     1681 atggagaaca ctttatcagc cgggaaataa tgcgggcaac ggtgtttaat tatatcgaat
     1741 gtgattacaa tcggtggcgg cggcacagtt ggtgtggcgg cctcagtccg gaacaatttg
     1801 aaaacaagaa cctcgctta
//
LOCUS       DAPOAV010000252         1765 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.260, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000252 DAPOAV010000000
VERSION     DAPOAV010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1765
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.260"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..689)
                     /gene="emrY"
                     /locus_tag="RN951_004650"
     CDS             complement(<1..689)
                     /gene="emrY"
                     /locus_tag="RN951_004650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrY"
                     /protein_id="HDX2529507.1"
                     /translation="MAITKSTPAPLTGGTLWCVTIALSLATFMQMLDSTISNVAIPTI
                     SGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQRIGELRLFLLSVTFFSLSSLMCSL
                     STNLDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPPEKRTFALALWSMTVIIAPICGPI
                     LGGYICDNFSWGWIFLINVPMGIIVLTLCLTLLKGRETETSPVKMNLPGLTLLVLGVG
                     GLQIMLDKGRDL"
     gene            complement(689..>1765)
                     /gene="emrK"
                     /locus_tag="RN951_004651"
     CDS             complement(689..>1765)
                     /gene="emrK"
                     /locus_tag="RN951_004651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter periplasmic
                     adaptor subunit EmrK"
                     /protein_id="HDX2529508.1"
                     /translation="GAYAYWSMELEDMISTDDAYVTGNADPISAQVSGSVTVVNHKDT
                     NYVRQGDILVSLDKTDATIALNKAKNNLANIVRQTNKLYLQDKQYSAEVASARIQYQQ
                     SLEDYNRRVPLAKQGVISKETLEHTKDTLISSKAALNAAIQAYKANKALVMNTPLNRQ
                     PQVVEAADATKEAWLALKRTDIKSPVTGYIAQRSVQVGETVSPGQSLMAVVPARQMWV
                     NANFKETQLTDVRIGQSVNIISDLYGENVVFHGRVTGINMGTGNAFSLLPAQNATGNW
                     IKIVQRVPVEVSLDPKELMEHPLRIGLSMTATIDTRNEDIAEMPDLASTVTSMPAYTS
                     KALVIDTSPIEKEISNIISHNGQL"
BASE COUNT          492 a          401 c          358 g          514 t
ORIGIN      
        1 agatcgcgcc ctttatcaag cataatttgc aagccaccaa caccgagcac taacagggtc
       61 agtcctggta gattcatttt gaccggtgaa gtctcagttt ctcttccttt aagtaaggtt
      121 aagcataatg tcaggacgat aatccccata gggacattga ttaaaaatat ccaaccccag
      181 ctaaagttat cgcaaatata accgcccaat atcggcccac atatcggagc gataatcacg
      241 gtcattgacc ataatgccag agcaaatgtt cttttttctg gtggataatt ccttaataat
      301 aaactctgtg acagtggaat taacggcccc gccattaatc cctgaacgac tctaaaaaat
      361 atcagcacat caagattggt cgataaacta cacattaagg aagacagcga aaaaaaagtg
      421 actgaaagta aaaataacct taattcgcct attctttgtg ccagcctgcc ggtaacaggg
      481 atcgcaatgg catttgctac gccaaacgag gtgataaccc aggtgccttc gtctgttgat
      541 gctcccagaa agccagatat tgtcggtatt gcgacgttag aaatagtgga atccaacatt
      601 tgcataaacg tcgctaatga caatgcaata gtaacgcacc ataacgtccc accggttaat
      661 ggtgccggag ttgatttagt gattgccatt aaagttgtcc attatgcgaa ataatgttgc
      721 taatttcttt ttctatcgga ctggtatcga taactaaagc cttactggta taagcaggca
      781 tagaggtcac ggttgaagcc agatcaggca tctcagcaat gtcttcgttc ctggtatcaa
      841 tagttgcagt catcgataaa ccaatgcgca aggggtgttc catgagttct tttggatcca
      901 gagaaacttc aaccggtaca cgctgaacga ttttgatcca gttccctgtc gcattttgtg
      961 caggtaataa ggagaacgca ttgccggttc ccatattgat ccctgtcacc cgaccatgaa
     1021 acacaacatt ttcaccataa agatcgctga taatattgac cgattgacca atccgtacat
     1081 ccgtgagttg tgtttcttta aagttggcat taacccacat ttgacgtgcc ggtacgacag
     1141 ccattaacga ttgtccgggg ctcactgttt cgccgacctg aacacttctc tgggcaatat
     1201 agccggtaac cggactctta atatccgtac gtttaagcgc caaccaggct tctttagttg
     1261 catccgccgc ttcaacgact tgtggctgac ggtttaatgg tgtgttcatt actaaagctt
     1321 tattcgcttt ataagcctgg atagcggcat tcaatgccgc tttgctactt attaacgtat
     1381 ctttggtatg ctccagcgtt tcttttgaaa taaccccctg cttcgctaac ggcactcgac
     1441 ggttataatc ttctaaagat tgttgatact gaatacgtgc tgaagcgact tcggcactgt
     1501 attgtttatc ctgtaagtat agtttattcg tttgccgaac aatatttgcc agattatttt
     1561 tagctttatt gagtgcgata gtggcatcag ttttatccag tgaaactaaa atgtcacctt
     1621 gtcgaacgta gttcgtatct ttatgattaa cgacagtgac actacctgag acttgtgcag
     1681 aaattggatc tgcattcccc gtgacatagg cgtcatctgt actaatcatg tcttctaatt
     1741 ccattgacca ataggcatag gcacc
//
LOCUS       DAPOAV010000253         1737 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.261, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000253 DAPOAV010000000
VERSION     DAPOAV010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1737
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.261"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(94..882)
                     /locus_tag="RN951_004652"
     CDS             complement(94..882)
                     /locus_tag="RN951_004652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA5"
                     /protein_id="HDX2529509.1"
                     /translation="MGEFFPAQVFKQLSHARAVIERHLAATLDTIHLFGSAIDGGLKP
                     DSDIDLLVTVSAAPNDSLRQALMLDLLKVSSPPGDGGTWRPLELTVVARSEVVPWRYP
                     ARRELQFGEWLRHDILSGTFEPAVLDHDLAILLTKARQHSLALLGPSAATFFEPVPKE
                     HFSKALFDTIAQWNAESDWKGDERNVVLALARIWYSASTGLIAPKDVAAAWVSERLPA
                     EHRPLICKARAAYLGSEDDDLAMRVEETAAFVRYAKATIERILR"
     gene            complement(1013..1486)
                     /locus_tag="RN951_004653"
     CDS             complement(1013..1486)
                     /locus_tag="RN951_004653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrA17"
                     /protein_id="HDX2529510.1"
                     /translation="MKISLISAVSENGVIGSGPDIPWSVKGEQLLFKALTYNQWLLVG
                     RKTFDSMGVLPNRKYAVVSKNGISSSNENVLVFPSIENALKELSKVTDHVYVSGGGQI
                     YNSLIEKADIIHLSTVHVEVEGDIKFPIMPENFNLVFEQFFMSNINYTYQIWKKG"
BASE COUNT          438 a          455 c          424 g          420 t
ORIGIN      
        1 tagttgagcg gcgggcgcag cccgtccgct tgaacgccga gttaggcatc agatgccctc
       61 ggcgcgggtc gatgcacttt tcgcacatgc cgctcaacgc aagattctct caatcgttgc
      121 tttggcatat cgaacgaacg cggccgtctc ttcgacgcgc attgctaggt cgtcgtcctc
      181 gctacccagg tacgccgcgc gtgccttgca gatgaggggc cgatgctcgg caggcaaacg
      241 ctccgatacc catgcggcag caacgtcctt aggagcaatg agaccagttg aagcgctgta
      301 ccaaatgcga gcaagagcaa gaacgacgtt ccgctcgtca cccttccaat ccgactctgc
      361 attccactgg gcaatagtgt cgaaaagcgc cttggagaaa tgctccttcg gcaccggctc
      421 gaaaaacgtg gctgcggatg ggcctagaag cgcaaggctg tgttgcctcg ccttggtcag
      481 caaaatcgca agatcgtgat ccagaacggc aggctcgaac gttccggaaa ggatgtcgtg
      541 gcggagccac tcaccgaact gaagctcacg ccgcgccgga tagcgccaag gcactacttc
      601 gcttcgagcg acaacagtta gctccagcgg tcgccatgtt ccgccatcgc ctggcggtga
      661 tgagactttc agcaaatcga gcattagcgc ctgccggagc gaatcgttag gtgcggcgct
      721 gacggtcacg agcaagtcta tgtcgctgtc cggcttcagc cctccatcga tcgcagatcc
      781 gaacaggtgg attgtgtcca gtgtcgcagc cagatggcgc tcgatcaccg cgcgagcgtg
      841 ggacagctgc ttgaaaactt gtgcagggaa aaattcaccc atgatgccta acgttaagtt
      901 cagcggcagc ttttaagttg cggctttgtg gaatactttt gcgcagcaaa accacaaaga
      961 cgcgacttaa aagctgtcca aggagcgaag cgactggtgc tgcaacgcat tgttagcctt
     1021 ttttccaaat ctggtatgta taatttatat tagacataaa aaactgttca aaaaccaaat
     1081 tgaaattctc aggcattata gggaatttga tatcaccttc gacttcaacg tgaacagtag
     1141 acaaatgaat tatatctgct ttttcaataa ggctattata gatttgaccc ccgccagaga
     1201 catatacatg atctgtaact tttgatagct ctttcaaagc attttctatt gaaggaaaaa
     1261 ctaggacgtt ttcatttgag cttgaaattc cgttctttga cactactgca tatttgcgat
     1321 ttggaagaac acccatagag tcaaatgttt ttcttccgac aaggagccat tgattatatg
     1381 tgagcgcttt aaagagtagt tgctcacctt ttactgacca cgggatatca ggaccactac
     1441 cgattacgcc attttctgac actgcagaaa tcaatgatat tttcaattta actcccttaa
     1501 tggctaactt tgttttaggg cgactgccct gctgcgtaac atcgttgctg ctccataaca
     1561 tcaaacatcg acccacggcg taacgcgctt gctgcttgga tgcccgaggc atagactgta
     1621 caaaaaaaca gtcataacaa gccatgaaaa ccgccactgc gccgttacca ccgctgcgtt
     1681 cggtcaaggt tctggaccag ttgcgtgagc gcatacgcta cttgcattac agtttac
//
LOCUS       DAPOAV010000254         1734 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.262, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000254 DAPOAV010000000
VERSION     DAPOAV010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1734
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.262"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..262)
                     /locus_tag="RN951_004654"
     CDS             complement(<1..262)
                     /locus_tag="RN951_004654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDX2529511.1"
                     /translation="MKKRNFSAEFKRESAQLVVDQNYTVADAAKAMDVGLSTMTRWVK
                     QLRDERQGKTPKASPITPEQIEIRELRKKLQRIEMENEILKKA"
     gene            complement(335..462)
                     /locus_tag="RN951_004655"
                     /pseudo
     CDS             complement(335..462)
                     /locus_tag="RN951_004655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477181.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
     gene            530..1569
                     /locus_tag="RN951_004656"
                     /pseudo
     CDS             530..1569
                     /locus_tag="RN951_004656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834167.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1837 domain-containing protein"
     gene            1550..>1734
                     /locus_tag="RN951_004657"
     CDS             1550..>1734
                     /locus_tag="RN951_004657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001352286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529512.1"
                     /translation="MNTLAAEIISQIKKHLEFKNDLSFLFAHSFLQNHKRTSFATKQS
                     KIGDENIVIYKRLIESA"
BASE COUNT          564 a          310 c          337 g          523 t
ORIGIN      
        1 tagccttttt taatatttca ttctccattt caatgcgttg tagctttttc ctcagctcac
       61 gtatttcgat ttgttctggt gttatcggag aggcttttgg tgttttgccc tgacgctcat
      121 cacgcagttg tttgacccat cttgtcattg tggaaaggcc aacatccata gctttggcgg
      181 catctgccac cgtgtagttc tggtcaacaa ccagttgagc ggattcgcgt ttaaactctg
      241 cgctgaaatt tctttttttc attggagcac ctgtgttgtt ctgaggtgag catatcacct
      301 ctgttcaggt ggccaaattc agtgtgccac ttcaaacaga cgaagaagtt attcgctttg
      361 gcgcgagttt tttaaagtcc ggatgacggt gttaatacca attttcagtg tcctggcggt
      421 atcgcgaacc ccggaaccat taaaggccat ttcagtgatc agataactcc taaggaactg
      481 attagaacgg cttcaaatca caactttaga cttagaggtt gaacagggaa tgaatgctga
      541 agatactaat tcattacata aaatatacaa tcctgtatat gggttgagta atatcgtatt
      601 acttgctaaa gagtgtcagt ctacagatcc agtaaaagtt aatcttctat gcctcggatt
      661 caaagaagat ctacctaaag acaaagagct tgcggaaact ctatttttag aattagttca
      721 ttattgcatt cctcatccag tgttagttaa acgaaaagag ttagcacgaa gtgagggaaa
      781 ggatgaggca agactttata gtgaacttgc aagggaagca cgcagccttt ttatgaaata
      841 caaattagaa agtgctgtaa aaataaaaaa tggtgaaccc cctgaaaagt tcgaacaacg
      901 agtgaaaaat gctaacttac gttatggtga agttggtgag ctaatatcat attgtatagc
      961 aattcatttt ttaaaagcgt cacaattagt ctcaaaaatg gctcttaaga catcctctga
     1021 aatgcctgtc tttggtcttg atggcattca tgcaaccata gacagtaaag gaacattgac
     1081 ggtattttac ctagaatcta aaatgaccag ggagtttgat agcggttctg aacaattttc
     1141 aaaatcagtt agtgggtttg aaagcgatag aaatagtcgt agaaatgaat acagaatact
     1201 gcaggacttg agtaatttag agtctcttga aggagaagaa cgaaaaaagg caatacaata
     1261 ctttgatcct tactctaatg aatcatcaaa tgtcagagag cgtttcgtta gaataattgc
     1321 ctacaatgaa gaaagctata aatctaaaat agctattgat gatgagtccc cactttccat
     1381 tcatttagac cactttaaaa aaattacgtc agcacttttg aagaaaaaat aaaaattatt
     1441 acgaacgatc tcgccaaagc aggagcaact ccgcaaaaat gtagagcgta catctttgcc
     1501 ttacctgacg ttgatgcttt taaattagat tttgcaaagg agttatctgg tgaacacttt
     1561 agctgctgaa atcattagcc aaataaaaaa acatttagag ttcaaaaacg acctcagttt
     1621 tctttttgca cactcttttt tgcaaaatca taaaagaacc tcttttgcta caaaacaaag
     1681 caaaattggc gatgaaaaca tagttattta taaaagatta attgaatctg cata
//
LOCUS       DAPOAV010000255         1686 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.263, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000255 DAPOAV010000000
VERSION     DAPOAV010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1686
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.263"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            134..502
                     /locus_tag="RN951_004658"
     CDS             134..502
                     /locus_tag="RN951_004658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HDX2529513.1"
                     /translation="MSDTLSGTTHPDDNDDHPWWGLPCTVTPCFGARLVQEGNRLHYL
                     ADRAGIRGRFRDADAYPLDQAFPLLMKQLKLMLTSGELNPRHQHTVTLYAKGLTCEAD
                     TLGSCGYVYLAVYPTPETKK"
     gene            592..969
                     /locus_tag="RN951_004659"
     CDS             592..969
                     /locus_tag="RN951_004659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HDX2529514.1"
                     /translation="MKTLPDTHVREVSCCPSPVTIWQTLLTRLLDQHYSLTLNDTPFV
                     DERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGFSACTHSQLINSIDILRARRATG
                     LMTRDNYRTVNNITLGKHPEAKR"
     gene            966..1168
                     /locus_tag="RN951_004660"
                     /pseudo
     CDS             966..1168
                     /locus_tag="RN951_004660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310834.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1181..1294
                     /locus_tag="RN951_004661"
     CDS             1181..1294
                     /locus_tag="RN951_004661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001161660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF957 domain-containing protein"
                     /protein_id="HDX2529515.1"
                     /translation="MQGIVPLTTETALLSCIKQAREDVLTLRHLQLLHQNR"
BASE COUNT          431 a          449 c          414 g          392 t
ORIGIN      
        1 tggctgagct cagacgccgc tgtggatgag gtcctgctca tcaacgaata cacctttacc
       61 gaagccggtc tgcgcgccgg ctgacccgtc atcgttaaac tatcattcac cgattttctg
      121 tgaggatttt atcgtgtcag acacactttc cgggacaacg catcccgatg acaatgacga
      181 ccatccctgg tggggactac cctgcacagt gacgccctgt ttcggcgccc gtctggtgca
      241 ggagggtaac cggttgcatt accttgccga ccgtgccggt atcagaggcc ggttcagaga
      301 tgcggatgcg taccctctgg accaggcctt tccgctgctg atgaaacaac tgaaattaat
      361 gctcaccagt ggtgaactga atccccgcca tcagcatacc gtgacactgt atgcgaaggg
      421 gctgacctgt gaagccgaca ccctcggctc ctgtggttac gtttatctgg ctgtttatcc
      481 gacacctgaa acgaaaaagt aaaccaccag aataaccttc tgctccggcc tggtgttttc
      541 accacgccac tgtcccattt tttatctctg catatcagga aaatcttcag tatgaaaaca
      601 ttacccgaca cgcatgtacg ggaggtatcg tgctgcccgt ctcccgtcac catctggcag
      661 acactgctca cccggttact ggaccagcat tacagcctta cgctgaatga cacaccgttc
      721 gtggatgaac gcgtgattga gcagcatatt gaggcaggca tttcactgtg tgatgcagtg
      781 aactttctcg tggaaaaata cgcactggta cgaactgacc agccgggatt cagcgcctgt
      841 acccactctc agttaataaa cagcatcgat atcctccggg ctcgccgggc aacaggcctg
      901 atgacccgcg acaattacag aacggtaaat aacattaccc tggggaagca tccggaggcg
      961 aaacgatgaa actagccctg acgctggaag ccgacagcgt taacgtgcag gcgctgaaca
     1021 tgggcgcatt gtcgttgacg tcgatggtgt taatctcgct gaactgatta acaaggtcgc
     1081 tgaaaacggt gattcactcc gcgtggtgga tgaacgtgac tctaccgaaa caccggcaac
     1141 ttatgccagc cctcaccagt tgctgtaaga caatgcagtg atacagggta tagtgccatt
     1201 aaccacagaa acagcactgt tgtcctgtat taagcaggca agagaagatg tccttaccct
     1261 gcgccatctg cagcttctgc accagaaccg gtgaatctca ctcaacaggc ttcatttccc
     1321 ctgacgccag cctgaataca gctggcgttt tcatttataa acagaaagga aaaccgataa
     1381 taatggaatg gacgccccta ccatgaagca acggtaggat attactgata aaccttccag
     1441 tggaggtgcg ttatggccgt tttaacgatt agcattgacc tgacaaaaaa tgaattccaa
     1501 atccacggtc tgggtaggaa cagaaaaatc taagctcaga aaacggatta aacgttccct
     1561 gatgcccgta ttcttcgcga atatgtcttc ctgtcggatt ggaatggagg tctgcgccgg
     1621 agcgcgtcat tagtgagaat gctgtctact taggggcata atgtcagact aatgcccgcg
     1681 atttgt
//
LOCUS       DAPOAV010000256         1669 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.264, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000256 DAPOAV010000000
VERSION     DAPOAV010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1669
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.264"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..373)
                     /locus_tag="RN951_004662"
     CDS             complement(<1..373)
                     /locus_tag="RN951_004662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase"
                     /protein_id="HDX2529516.1"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGY
                     IELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVE
                     YSPVTEKHLTDGMTVRELCSAA"
     gene            complement(556..1113)
                     /locus_tag="RN951_004663"
     CDS             complement(556..1113)
                     /locus_tag="RN951_004663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDX2529517.1"
                     /translation="MRLFGYARVSTSQQSLDLQVRALKDAGVKANRIFTDKASGSSTD
                     REGLDLLRMKVEEGDVILVKKLDRLGRDTADMIQLIKEFDAQGVAVRFIDDGISTDGD
                     MGQMVVTILSAVAQAERRRILERTNEGRQEAKLKGIKFGRRRTVDRNVVLTLHQKGTG
                     ATEIAHQLSIARSTVYKILEDERAS"
     gene            1415..>1669
                     /locus_tag="RN951_004664"
     CDS             1415..>1669
                     /locus_tag="RN951_004664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006939175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDX2529518.1"
                     /translation="MTDFKWRHFQGDVILWAVRWYCRYPISYRDLEEMLAERGISVDH
                     TTIYRWVQCYAPEMEKRLRWFWRRGFDPSWRLDETYVKVRG"
BASE COUNT          424 a          414 c          397 g          434 t
ORIGIN      
        1 tggcagcact gcataattct cttactgtca tgccatccgt aagatgcttt tctgtgactg
       61 gtgagtactc aaccaagtca ttctgagaat agtgtatgcg gcgaccgagt tgctcttgcc
      121 cggcgtcaac acgggataat accgcaccac atagcagaac tttaaaagtg ctcatcattg
      181 gaaaacgttc ttcggggcga aaactctcaa ggatcttacc gctgttgaga tccagttcga
      241 tgtaacccac tcgtgcaccc aactgatctt cagcatcttt tactttcacc agcgtttctg
      301 ggtgagcaaa aacaggaagg caaaatgccg caaaaaaggg aataagggcg acacgaaaat
      361 gttgaatact catactcttc ctttttcaat attattgaag catttaccag ggttattgtc
      421 tcatgagcgg atacatattt gaatgtattt agaaaaataa acaaataggg gttccgcgca
      481 catttccccg aaaagtgcca cctgacgtct aagaaaccat tattatcatg acattaacct
      541 ataaaaatag gcgtatcacg aggccctttc gtcttcaaga attttataaa ccgtggagcg
      601 ggcaatactg agctgatgag caatttccgt tgcaccagtg cccttctgat gaagcgtcag
      661 cacgacgttc ctgtccacgg tacgcctgcg gccaaatttg attcctttca gctttgcttc
      721 ctgtcggccc tcattcgtgc gttctaggat cctccggcgt tcagcctgtg ccacagccga
      781 caggatggtg accaccattt gccccatatc accgtcggta ctgatcccgt catcaatgaa
      841 ccggactgcc acgccctgag cgtcaaattc ctttatcagt tggatcatat cggcagtgtc
      901 gcggccaaga cggtcgagct tcttaaccag aatgacatca ccttcctcca ccttcatcct
      961 cagcaaatcc agcccttccc ggtctgttga actgccggat gccttatcgg taaatatacg
     1021 gtttgctttc acacctgcgt ctttgagtgc tctgacctga agatcaagag actgctgact
     1081 ggttgagacc cgagcgtaac caaaaagtcg cataaaaatg taccttaaat cgaatatcgg
     1141 acaactcatg tctattatta caaatttacg atttaataga catattaatg taacagtttt
     1201 acgatgtccg ataatttata acatttcgta cggttggaaa aatgttacta aatgcccgtc
     1261 aggcagggag gccgatatgc ccgttgactt tctgaccact gagcagactg aaagctatgg
     1321 cagattcacc ggtgaaccgg atgagcttca gctggctctg ttgcaaaaat cgtgaagctt
     1381 gagcatgctt ggcggagatt ggacggacgg aacgatgacg gatttcaagt ggcgccattt
     1441 ccagggtgat gtgatcctgt gggcggtgcg ctggtattgt cgctatccga tcagctatcg
     1501 cgaccttgag gaaatgctgg cggaacgcgg catttcggtc gaccatacga cgatctatcg
     1561 ctgggtccag tgctacgccc cggagatgga gaagcggctg cgctggttct ggcggcgtgg
     1621 ctttgatccg agctggcgcc tggatgaaac ctacgtcaag gtgcggggc
//
LOCUS       DAPOAV010000257         1662 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.265, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000257 DAPOAV010000000
VERSION     DAPOAV010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1662
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.265"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(204..857)
                     /gene="ribB"
                     /locus_tag="RN951_004665"
     CDS             complement(204..857)
                     /gene="ribB"
                     /locus_tag="RN951_004665"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3,4-dihydroxy-2-butanone-4-phosphate synthase"
                     /protein_id="HDX2529519.1"
                     /translation="MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMI
                     FPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAA
                     EGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDL
                     MTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS"
     regulatory      complement(961..1109)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            1231..1521
                     /gene="ubiK"
                     /locus_tag="RN951_004666"
     CDS             1231..1521
                     /gene="ubiK"
                     /locus_tag="RN951_004666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417514.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis accessory factor UbiK"
                     /protein_id="HDX2529520.1"
                     /translation="MIDPKKIEQIARQVHESMPKGIREFGEDVEKKIRQTLQAQLTRL
                     DLVSREEFDVQTQVLLRTREKLALLEQRISELENRSTEIKKQPDPETLPPTL"
BASE COUNT          485 a          411 c          362 g          404 t
ORIGIN      
        1 tttttcggat atattcatat ggtcgcataa taacggaaca attatatgat tttgatcata
       61 atgaaaaaga atgcctgata ttaatgaaat tttctcatag aaagagaagc ggaattaaca
      121 tcttgcatag cagggaaaaa taaaaaccga agcctgctac aacttcggtt tcttgattaa
      181 ggcagtaaat taagcagcgg ttttcagctg gctttacgct catgtgcctg acggtatgcc
      241 accaggtctt caatagtcac gagcgccata ttgtgtttat tggcaaactc aatacactct
      301 ggtgcacgcg ccatcgtgcc atcgtcatta gtcagctcac acagtacacc agccggttta
      361 aagcctgcca gcgtcatcag atcaatagtt gcttcagtat gaccgccacg cgtcagtaca
      421 ccacctgcct gagcgcgaag tgggaaaacg tggccaggac gattcagatc tgacggtttt
      481 gcgccatcgg caatcgctgc gcgaacggtc gtaatacggt cagcggcaga aacaccggta
      541 gtcacacctt cagctgcttc aatggtcacg gtaaaaccgg tgccataggc gctggtgtta
      601 ttttctacca tcattggcag atcgagttgt ttacggcgat cttcagtaat gcacaggcaa
      661 acaataccgc taccgtggcg aatggtcagc gccatctgct caacagtcat ggtttctgcc
      721 gggaagatca tatcaccttc gttttcacgg tcttcatcat caagcaccat tacaccgcgt
      781 ccttcacgca gcgcagccag tgcattttca acacgttcga aaggcgtacc aaaagaggaa
      841 agtagcgtct gattcatggt aaaaaaacct cactaaaatt atggttacca gaatcagggc
      901 agtcttagga gtggcggcat atagccaaaa taacgtgagc gggtccatgc ccgacagaat
      961 cgttactctc tcccatccgg actctaaccg tcggccccgg aattacaccg gatctgctgt
     1021 cctttgagtt cgcacccaaa gcgctcgcgg gctttcaact gagttgattt accgccggtg
     1081 gggaatttcg ccccgccctg agaataagcg gattcactat aacgctaatg attagcggca
     1141 gcaacgcata gcttcacata attctggttt atgacttacc cttatcgcac tacaatggca
     1201 ctcaacacct atcagtacag ggaaactaca atgattgacc cgaaaaaaat tgagcaaatc
     1261 gctcgccagg ttcacgaatc aatgcctaaa ggaatcaggg agttcgggga agatgtggag
     1321 aaaaaaatcc gccaaaccct acaagcgcag ctgacgcgcc tcgaccttgt aagccgtgaa
     1381 gagttcgacg tccaaacgca agtcctgtta cggactcgtg aaaaactggc gctgcttgaa
     1441 caaagaatca gcgaactgga aaatcgcagt actgagatca aaaagcagcc agatccagag
     1501 actctccccc caacgctgta aacattcgtc tttaatgcac tgtaaattat gaattaatcc
     1561 tctaatttat agtgctttct attaccttat cgcgtaatcc cattcagaaa accatcacaa
     1621 aaatgaatga gtacaattga aagtataatt gcaatgtatt tt
//
LOCUS       DAPOAV010000258         1619 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.266, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000258 DAPOAV010000000
VERSION     DAPOAV010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1619
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.266"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..343
                     /locus_tag="RN951_004667"
     CDS             <1..343
                     /locus_tag="RN951_004667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309324.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDX2529521.1"
                     /translation="AWHTRLMEDGVQAMRDYLAGLDIASPEHQVLMNVTAKSEVAPSI
                     IKENLSLHLTHTVKWTESLDTFLNMPTPVAFLEISNKPYLGNMLNDFAGVDQQRVMHC
                     RKAFSDAKVFK"
     gene            340..1326
                     /locus_tag="RN951_004668"
     CDS             340..1326
                     /locus_tag="RN951_004668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529522.1"
                     /translation="MIPDYLTFIRFQDKRNLIYIYAIGLILIGFYWKNAGFTFPSEDI
                     GVVSGILALVLYNFIFDLKAYWAYKCVTKNIDFSWFKKKQNHKIELFLTQPLVAGFLS
                     LIMLSAMSWGLYQLLPSLYALFLISLLGPLVIFLLFRMIRTSYVKQVAISVAKKVKYK
                     SLTRYVLLSVCISTVVNLLTISPLRNSDSFVTEGQWLTFKSIIALLILCGVVLAINLF
                     FLRFSKRYAFLGRLFLQEIDLFFSSENALSTFFAKPLWLRLFILLVIEVMWITLVSVL
                     ATLVEWRIWFEAYFLLCYVPCLIYYFFYCRFLWHNDFMMACDMYFRWGHFNK"
BASE COUNT          380 a          317 c          386 g          536 t
ORIGIN      
        1 tgcctggcac acgcgtttga tggaagacgg cgttcaggca atgcgcgatt atcttgccgg
       61 actggatatc gcttcgccag agcatcaggt tctgatgaac gtaacagcaa aaagcgaggt
      121 cgctccgtca attatcaaag aaaatctctc attacactta actcatacgg tgaaatggac
      181 tgaatctctc gatacatttc tgaatatgcc aaccccggta gctttccttg aaataagtaa
      241 taagccctat ttggggaata tgttaaatga ttttgctggc gtggatcagc aacgagttat
      301 gcattgtcgt aaagcattta gtgatgcaaa ggtattcaaa tgattcctga ttatttaact
      361 tttattcgct ttcaggataa acgaaatctg atatacattt atgctattgg acttattctg
      421 ataggctttt attggaagaa tgcagggttt acttttccat cagaggatat tggtgtagtt
      481 agtgggattc tggctctggt gctgtataat tttatttttg atctcaaggc gtactgggct
      541 tataaatgcg tcacgaagaa tatcgatttt tcgtggttta agaaaaagca gaaccacaaa
      601 atagaattat ttcttacaca acctctggtg gcaggatttc tgtcgttaat catgttgagt
      661 gcaatgagtt gggggctata ccagcttcta ccctcgttat atgcgctgtt cctgatttcg
      721 ttacttgggc cgttggtcat ctttctgctg tttcggatga tccgcaccag ttatgtcaag
      781 caggtcgcta tttcagtagc gaaaaaagta aaatataaaa gtctgactcg ctatgtgctg
      841 ctttcggtgt gcatctcaac ggttgttaac ctgcttacta tcagcccgtt gcgtaacagt
      901 gattcttttg tgacagaggg gcagtggtta acgtttaaat cgataattgc attgctcatt
      961 ctttgtggcg tagtgttggc gattaatctg ttttttctgc gcttctccaa gcggtacgct
     1021 tttctgggca ggcttttttt gcaggaaatc gatctgtttt tctccagtga aaatgcgttg
     1081 tcgacctttt ttgccaagcc gctttggctt cggttattca tattgctggt tattgaagtg
     1141 atgtggatta cgctggtgtc ggtattggca acgcttgtag aatggcggat ttggtttgaa
     1201 gcctattttt tactctgcta tgtaccgtgc ttaatttact attttttcta ttgtcgattc
     1261 ctctggcata acgattttat gatggcatgt gacatgtatt tccgttgggg gcattttaat
     1321 aagtgaggaa gtgataggaa gtgaccagat aatacatata tgttctgtac tctcttgcgc
     1381 attttgattg ttgactgagt aaccagacag ttgatgtgca cgatttcccc tcgccctaac
     1441 agacgtgggc gggggcaccc ggtgtgtgca atatacgaaa aaaaagcccg tactttcgta
     1501 cgagctcttc tttaaatatg gcggtgaggg ggggattgac tcgcttcgct cgccctgcgg
     1561 gcagcccgct cactgcgttc acggtctgtc caactggctg tcgccagttg tcgaacccc
//
LOCUS       DAPOAV010000259         1597 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.268, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000259 DAPOAV010000000
VERSION     DAPOAV010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1597
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.268"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            308..748
                     /locus_tag="RN951_004669"
     CDS             308..748
                     /locus_tag="RN951_004669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529523.1"
                     /translation="MSKDVERITQINDQGEIIGGFVAVIRPKQKSAFQRHFTMNQDAL
                     RILAKELTGEQFKVLMLMLADLDYENFIQIAQADIAETLGMQKTNVSRAVRALLDVGV
                     IFEGPKVGRSKTYRLNEQFGWKGTVTNHKKALKNGFSVIQGGRI"
     gene            complement(1021..1260)
                     /locus_tag="RN951_004670"
                     /pseudo
     CDS             complement(1021..1260)
                     /locus_tag="RN951_004670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639531.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rep protein"
BASE COUNT          443 a          385 c          412 g          357 t
ORIGIN      
        1 aaaaaacgtg caggagctgt tgaacgtgaa aaccacgaaa tctggcaaaa atcacagctg
       61 acgaggcttg cagaggagta agccagtata cactccgcta tcgctacgtg actgggtcat
      121 ggctgcgccc cgacacccca aagagcagct aggataaata tctaatggaa tcaatgcgtt
      181 agatgcctaa tataaagata cagaaaggag aataaaaaca ttaataaaat ctaagggtta
      241 cagttgacat agttatcaat aatgataaca ctgttatcat tattgataac tcaaataggg
      301 ttcaaagatg agtaaggatg tcgagagaat cactcagata aatgaccagg gtgagattat
      361 cggcggcttc gttgccgtta tccgccctaa acaaaaatca gcatttcaga ggcatttcac
      421 catgaatcaa gacgcattac ggatcttggc taaggaatta accggggagc aattcaaggt
      481 cttaatgctg atgcttgcag atctggatta cgaaaacttc attcagatcg cccaagcaga
      541 tattgctgaa actttaggga tgcagaaaac gaatgttagt cgcgccgttc gcgcgctact
      601 ggatgttggg gtgatctttg agggacctaa agttggcaga tcaaaaacat accggctgaa
      661 tgaacaattt ggttggaaag gcaccgtaac caaccacaaa aaggcactca aaaacggctt
      721 tagtgtcatt cagggcggcc gaatttaaag agccagcggc aggcggacaa tcaggggcta
      781 cgtgttaacg ttttgaccat gattgtctat cctgcattgc tcttttgccg cctcaaaatc
      841 ccttgcattt tttgcacccc cgttctccag aactacgcaa ttcgaacagg tcctgtgact
      901 agacgttgat cgggcaatac gctaaaacac ttccgcgcgt ttctggcata aaccaaccat
      961 gggatggttt gtgttagcag caagcgccag aaacgcgctc aatctaatct tcgccatcgt
     1021 ttgccacggt ttcggcagcg ccttgagcgc aaccggaaac cgtctgggga gaaccccaga
     1081 cccccattgc tgtaatatca acggtctacg accacctacc agctgagtga ctgcctgttc
     1141 cgtgcagttg ggctttgcag ggggctggcg cggttcctgg cgacctgaaa gcccctggtt
     1201 aggggtatcg gcgcgcctga cctcctgaga gcctctgtaa gcgtttttcg cgccttccat
     1261 gccctgacgg gcatttaaaa cccgtttcgt gcgtctgaga gcttctgagc gcgtttgaag
     1321 ggctatctga cgactcatcc ccgaaagaac aacaacggaa tcacaggcaa tatgcgagag
     1381 gtgacaccgc tcgccgcagc cccagcgacc gaacgtagtg agcgagtggg cgaggaagcg
     1441 gaagagaacc ggaaaccaca ttgagcacgt acgcactgat gcggggtgtc ggggtgaagc
     1501 cctgaccaga tggcaaacgg aatatcgtcg cgggtgacgg tattacattt gcacatcctg
     1561 tcccgatttc tgcggagttt aacggtgaac ggacggc
//
LOCUS       DAPOAV010000260         1596 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.269, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000260 DAPOAV010000000
VERSION     DAPOAV010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1596)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1596)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1596
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.269"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            56..427
                     /locus_tag="RN951_004671"
     CDS             56..427
                     /locus_tag="RN951_004671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004924490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX2529524.1"
                     /translation="MQLRYDDKQFHTTVIKDVLLWIEHNLDQSLLLDDVANKAGYTKW
                     YFQRLFKKVTGVTLASYIRARRLTKAAVELRLTKKTILEIALKYQFDSQQSFTRRFKY
                     IFKVTPSYYRRNKLWELEAMH"
     gene            complement(437..>1596)
                     /locus_tag="RN951_004672"
     CDS             complement(437..>1596)
                     /locus_tag="RN951_004672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001339197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS4-like element ISVsa5 family transposase"
                     /protein_id="HDX2529525.1"
                     /translation="LHLKRLNSLTLACHALLDCKTLTLTELGRNLPTKARTKHNIKRI
                     DRLLGNRHLHKERLAVYRWHASFICSGNTMPIVLVDWSDIREQKRLMVLRASVALHGR
                     SVTLYEKAFPLSEQCSKKAHDQFLADLASILPSNTTPLIVSDAGFKVPWYKSVEKLGW
                     YWLSRVRGKVQYADLGAENWKPISNLHDMSSSHSKTLGYKRLTKSNPISCQILLYKSR
                     SKGRKNQRSTRTHCHHPSPKIYSASAKEPWVLATNLPVEIRTPKQLVNIYSKRMQIEE
                     TFRDLKSPAYGLGLRHSRTSSSERFDIMLLIALMLQLTCWLAGVHAQKQGWDKHFQAN
                     TVRNRNVLSTVRLGMEVLRHSGYTITREDLLVAATLLAQNLFTHGYALGKL"
BASE COUNT          432 a          309 c          369 g          486 t
ORIGIN      
        1 aggttatttt atgtatattg aacagcattc tcgctatcaa aataaagcta ataacatcca
       61 attaagatat gatgataagc agtttcatac aacggttatc aaagatgttc tattatggat
      121 tgaacataat ttagatcagt ctttactgct tgatgatgtg gcgaataaag cgggttatac
      181 caagtggtat tttcagcggc tgttcaaaaa agtaacaggg gtcacactgg ctagctatat
      241 tcgtgctcgt cgtttgacga aagcggctgt tgagttgagg ttgacgaaaa aaactatcct
      301 tgagatcgca ttaaaatatc aatttgattc ccaacaatct tttacacgtc gatttaagta
      361 catttttaag gttacaccaa gttattatcg gcgtaataaa ttatgggaat tggaggcaat
      421 gcactgagag atcccctcat aatttcccca aagcgtaacc atgtgtgaat aaattttgag
      481 ctagtagggt tgcagccacg agtaagtctt cccttgttat tgtgtagcca gaatgccgca
      541 aaacttccat gcctaagcga actgttgaga gtacgtttcg atttctgact gtgttagcct
      601 ggaagtgctt gtcccaacct tgtttctgag catgaacgcc cgcaagccaa catgttagtt
      661 gaagcatcag ggcgattagc agcatgatat caaaacgctc tgagctgctc gttcggctat
      721 ggcgtaggcc tagtccgtag gcaggacttt tcaagtctcg gaaggtttct tcaatctgca
      781 ttcgcttcga atagatatta acaagttgtt tgggtgttcg aatttcaaca ggtaagttag
      841 ttgctagaac ccatggctcc tttgccgacg ctgagtagat tttaggtgac gggtggtgac
      901 aatgagtccg tgtcgagcgc tgattttttc ggcctttaga gcgagattta tacaatagaa
      961 tttggcatga gattggattg cttttagtca gcctcttata gcctaaagtc tttgagtgac
     1021 tagatgacat atcatgtaag ttgctgatag gtttccagtt ttccgctcct aggtctgcat
     1081 attgtacttt tcctcttact cgacttaacc agtaccaacc cagcttctca acggatttat
     1141 accatggcac tttaaagcca gcatcactga caatgagcgg tgtggtgtta ctcggtagaa
     1201 tgctcgcaag gtcggctaga aattggtcat gagctttctt tgaacattgc tctgaaagcg
     1261 ggaacgcttt ctcataaaga gtaacagaac gaccgtgtag tgcgactgaa gctcgcaata
     1321 ccataagtcg tttttgctca cgaatatcag accagtcaac aagtacaatg ggcatcgtat
     1381 tgcccgaaca gataaagcta gcatgccaac ggtatacagc gagtcgctct ttgtggaggt
     1441 gacgattacc taacaatcgg tcgattcgtt tgatgttatg ttttgttctc gctttggttg
     1501 gcaggttacg gccaagttcg gtaagagtga gagttttaca gtcaagtaat gcgtggcaag
     1561 ccaacgttaa gctgttgagt cgttttaagt gtaatt
//
LOCUS       DAPOAV010000261         1576 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.270, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000261 DAPOAV010000000
VERSION     DAPOAV010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1576
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.270"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(50..1456)
                     /gene="gndA"
                     /locus_tag="RN951_004673"
     CDS             complement(50..1456)
                     /gene="gndA"
                     /locus_tag="RN951_004673"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HDX2529526.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIA
                     ENPGKKLVPYYTVQEFVESLETPRRILLMVKAGAGTDSAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILKQIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYALLKGGLALSNEELAQT
                     FTEWNEGELSSYLIDITKDIFTKKDEEGNYLVDVILDEAANKGTGKWTSQSSLDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASDEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYSQNAGIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFSAAIAYYDSYRSAVLPANLIQAQRDYFGA
                     HTYKRTDKEGVFHTEWLD"
BASE COUNT          425 a          399 c          362 g          390 t
ORIGIN      
        1 tttattatta gaccttcaat aaagatatga aggtctaata atataaatat taatctaacc
       61 actcagtgtg gaaaacgcct tctttatcag tgcgcttata ggtgtgcgca ccaaagtaat
      121 cacgctgagc ctgaatcagg ttagcgggca gaacagcgga acggtagctg tcatagtagg
      181 caattgcggc agagaacgtt ggtaccggaa taccattctg cacggcatag gccacgacat
      241 cacgcagtgc ctgctgatag tcatcagcga tctgtttgaa gtacggtgcc agcaggaggt
      301 tagcaatgcc agcgttttgc gaataagcat cggtgatctt ctgcaggaac tgcgcacgaa
      361 tgatgcagcc agcgcggaaa atcttagcga tctcgccgta gttaagatcc cagttgtatt
      421 catcagaagc agcacgcagc tgggagaagc cctgagcata ggaaacgatt ttaccgaggt
      481 acaacgcacg acgaactttt tcgataaatt cagctttatc accggccggc tgagcctgcg
      541 gaccactcag cactttcgaa gcggctacac gctggtcttt cagagaagag atataacgag
      601 caaaaacaga ctcggtgatc agagacagag gttcgccgag atccagtgag ctttggctgg
      661 tccacttgcc ggtaccttta tttgcggctt catcaagaat aacatcaacg aggtagttac
      721 cctcttcatc cttcttggtg aagatatctt tagtaatgtc gatcaagtag ctgctcagtt
      781 caccttcgtt ccattcggta aaggtttgcg ccagctcttc gttggatagt gccagaccac
      841 ctttcaaaag cgcataagct tcagcaatca gctgcatgtc accatactcg atgccgttat
      901 gaaccatctt cacataatgg ccagcaccgt cagcacctat ataagtcaca cacggctcac
      961 cgtcttcagc aaccgccgcg atctgcttca gaatcggagc aaccagctca taggcttctt
     1021 tctgcccacc aggcatgatg gaaggccctt tcagagcccc ctcttcacca ccggaaacac
     1081 cggtaccgat aaagttaaaa ccttcggcag acaattcacg gttacgacgg atggtgtcct
     1141 ggaagaaggt gttgccacca tcaatgatga tgtcgccttt atcaaggtaa ggcttcaggg
     1201 aatcgatggc gctatctgta ccagccccag ccttcaccat caacaggata cggcgtggtg
     1261 tttcaaggga ttcaacaaac tcttgtactg tgtagtaagg gaccagtttc ttgccaggat
     1321 tttcagcaat cacttcttcg gtcttttcac gggagcggtt gaaaacggag acggtataac
     1381 cacggctttc gatgttgagc gctagattac gccccataac tgccataccg acaaccccga
     1441 tctgttgctt agacattaca tactcctgtc tggtttgatc gccgcgacaa gtacgcagct
     1501 catttcgata ttatacgact gggcattact aaacatagat aaatgcgcca atataaactt
     1561 caatttatca actgca
//
LOCUS       DAPOAV010000262         1481 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.271, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000262 DAPOAV010000000
VERSION     DAPOAV010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1481
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.271"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            128..1357
                     /locus_tag="RN951_004674"
     CDS             128..1357
                     /locus_tag="RN951_004674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease"
                     /protein_id="HDX2529527.1"
                     /translation="MSNIWSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAVVLFITA
                     LVAWPLTYWPHKALCQFILSSKTSAGEGITGAVTHYYGKKIGNLITTLYFIAFFVVVL
                     IYAVAITNSLTEQLAKHMVIDLRIRMLVSLGVVLILNLIFLMGRHATIRVMGFLVFPL
                     IAYFLFLSIYLVGSWQPDLLTTQVEFNQNTLHQIWISIPVMVFAFSHTPIISTFAIDR
                     REKYGEHAMDKCKKIMKVAYLIICISVLFFVFSCLLSIPPSYIEAAKEEGVTILSALS
                     MLPNAPAWLSISGIIVAVVAMSKSFLGTYFGVIEGATEVVKTTLQQVGVKKSRAFNRA
                     LSIMLVSLITFIVCCINPNAISMIYAISGPLIAMILFIMPTLSTYLIPALKPWRSIGN
                     LITLIVGILCVSVMFFS"
BASE COUNT          359 a          332 c          311 g          479 t
ORIGIN      
        1 cacgtaaggt ttgcaaccac taacccacca atagaggggt agatagggcg ttaatctccc
       61 atacttaacc tggtttatgg taaattgccc tccattttgt ttaatttgta gatgatacgt
      121 tcagataatg tctaatattt ggtctaaaga agaaactctg tggagtttcg cgctctacgg
      181 cacagccgtt ggtgcaggca cgctcttcct tcctattcag ttaggttcgg caggggctgt
      241 ggtcctgttt attactgctc tggtcgcctg gcctttaaca tattggccac ataaagcctt
      301 atgccagttc atcctctcat cgaaaacatc agcaggtgaa gggataacgg gcgcagtaac
      361 acactactat ggcaagaaga ttggtaatct gattaccacg ctgtacttca tcgccttttt
      421 tgtcgtcgtg ttgatatatg cagtggcaat taccaactca cttacggaac agctggcaaa
      481 gcatatggtt attgatcttc gcatccgtat gttggtgagt ctgggtgttg tattaatcct
      541 gaatctcatt tttctgatgg gacgccatgc aaccattcgg gtaatgggtt ttttggtatt
      601 cccattgatt gcctatttct tatttctttc catttacctt gtcggtagtt ggcaacctga
      661 tctattaacg acccaggtag agttcaatca gaataccctt caccagatat ggatatcgat
      721 tcccgtgatg gttttcgcct ttagccatac gcccattatt tctacgtttg ccatagacag
      781 acgtgaaaaa tatggcgaac acgctatgga taaatgcaaa aaaattatga aagtcgctta
      841 tctcatcatc tgcataagtg tactgttctt tgtctttagc tgcctgcttt ctattccacc
      901 ttcgtatatt gaagcggcta aagaagaagg ggtcaccatt ttatcggcgc tttctatgct
      961 gccgaacgcc ccagcatggc tgtcaatttc cgggattatt gtcgcagtag ttgcgatgtc
     1021 gaaatcattc ctgggtacgt actttggcgt tattgaaggt gccacggagg tcgtcaaaac
     1081 aacactacag caggttggtg taaagaaaag tcgtgcattt aaccgcgcac tatcaattat
     1141 gttggtatcg ctgatcacct tcattgtttg ttgcattaac ccgaacgcga tttcgatgat
     1201 ttacgcgatc agcggcccgc tcattgccat gatacttttc atcatgccta cgttgtcaac
     1261 gtatctgatc ccggcgctta aaccctggcg ttccatcgga aatctgatta cgctgatcgt
     1321 gggtatcctg tgcgtatcgg taatgttctt tagctgatat ccattgtgaa tggttcaaaa
     1381 ttgctacaat tttgaaccat tccagttttc ataatgttca ttcgttatta ttccgcacta
     1441 tcacttccct catcatatcc tagtattatc agttagttaa a
//
LOCUS       DAPOAV010000263         1446 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.272, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000263 DAPOAV010000000
VERSION     DAPOAV010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1446
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.272"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..726
                     /locus_tag="RN951_004675"
     CDS             <1..726
                     /locus_tag="RN951_004675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4329 domain-containing protein"
                     /protein_id="HDX2529528.1"
                     /translation="DEWGNQLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYDPLQ
                     GRYITQDPIGLKGGWNLYGYQLNPISDIDPLGLSMWEDAKSGACTNGLCGTLSAMIGP
                     DKFDSIDSTAYDALNKINSQSICEDKEFAGLICKDNSGRYFSTAPNRGERKGSYPFNS
                     PCPNGTEKVSAYHTHGADSHGEYWDEIFSGKDEKIVKSKDNNIKSFYLGTPSGNFKAI
                     DNHGKEITNRKGLPNVCRVHGNM"
     gene            698..1081
                     /locus_tag="RN951_004676"
                     /pseudo
     CDS             698..1081
                     /locus_tag="RN951_004676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417940.2"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YbbC/YhhH family protein"
     gene            1186..1428
                     /locus_tag="RN951_004677"
                     /pseudo
     CDS             1186..1428
                     /locus_tag="RN951_004677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418051.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lyase"
BASE COUNT          507 a          227 c          332 g          380 t
ORIGIN      
        1 gatgaatggg gtaaccagct gaatgaagag aacccgcacc agctgcagca gctcatccgc
       61 ctgccggggc agcagtatga tgaggagtcc ggcctgtatt ataaccgcca ccgctattat
      121 gacccgctgc aggggcggta tatcactcag gatccgattg gactgaaggg gggatggaac
      181 ctgtatggat atcaattgaa tccgatatca gacatcgacc ccctgggttt atctatgtgg
      241 gaggatgcaa aatcgggggc atgtactaat ggtctttgcg gcacactatc cgctatgata
      301 ggtccagata aatttgattc tatagatagc accgcatatg acgccttaaa taaaataaat
      361 agccaatcta tttgcgaaga taaagagttc gctggtttaa tatgtaagga taatagtggc
      421 agatatttct caacagcacc taaccgagga gaaagaaaag gatcatatcc attcaatagc
      481 ccttgcccta atggtactga gaaagtatca gcttatcata ctcatggtgc agatagtcat
      541 ggagaatatt gggacgaaat attttcaggt aaagatgaga aaatagttaa aagtaaagat
      601 aacaatatca agtcatttta tttaggtacg cccagtggta attttaaagc aatagataac
      661 cacgggaagg aaataacaaa cagaaaagga ttacctaatg tctgcagagt tcatggtaat
      721 atgtaaaaaa atattgttta ggaactgtgt cattgtatct ttgtttgttt ttacatacaa
      781 cacatgggcg cagtgtaata ataatattaa aataatgcgc aagtatgaaa gtgaaggtaa
      841 atataccgtt agaaatttgg ttaaaaataa agctatagca ttggaattag ctgagatata
      901 tgttaagaat cgttatggac aggatgccgc agaagaagaa aaaccatact aaatcactga
      961 gttaacaacg agttgggttg ttgaaggtac cattcactca gaccaaattg ctggtggggt
     1021 ttttattata gaaataggca aaaatgatgg gagaattctg aattttggcc acggaaaata
     1081 agtatgtaag gataatcaaa catcgtgtgc gctgatggca gagtaggtgg aggactccag
     1141 acagtcaaac gatagaaaaa gatagccttt atggaggttc ctgcaatgtc aaatacatac
     1201 cagaaaagaa aggcaagtaa agagtatggt ttatataata aatgtaagaa actaaatgat
     1261 gatgaattat ttcgcttact tgatgatcgc aattccttga aaaggatttc atctgccaga
     1321 gtattacagt taagaggggg gcaagacgct gttagattgg caattgaatt ctgcactgac
     1381 aaaaattata tccgtagaga tatcggagca tttatactcg ggcaaatata aatttgcaaa
     1441 aaatgc
//
LOCUS       DAPOAV010000264         1400 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.274, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000264 DAPOAV010000000
VERSION     DAPOAV010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1400
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.274"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(10..1368)
                     /locus_tag="RN951_004678"
     CDS             complement(10..1368)
                     /locus_tag="RN951_004678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDX2529529.1"
                     /translation="MEKDYLRISSTVLVSLLFGLALVLVNSWFNQPGVEEVVPRSTYL
                     MVMIALFFIDTVAFIFMQLYFIYDRRQFSNCVLSLAFLSCLIYFVITVIIIQQIIEER
                     LTSSVVQNDIAIYYLFRQMSLCILIFLALVNKVSENTKQRNLFSKKMTLCISLFFVFG
                     GPIVAHILSSHYESYNLHIAELTNENGQVVWKASYVTIMIFMWLTLLSVNLYFNGLRY
                     DIWNGVTVIAFCAVLYNISLLFMSRYSVSTWYISRTIEVVSKLTVMVIFMCHIFSALR
                     VTKNIAHRDPLTNIFNRNYFFNELTVQSASAQKTPYCVMIMDIDHFKKVNDTRGHPVG
                     DQVIKTVVNIIGKSIRPDDLLARVGGEEFGVLLTDIDTERAKALAERIRENVERLTGD
                     NPEYAIPQKVTISIGAVVTQENALNPNEIYRLADNALYEAKETGRNKVVVRDVVNFCE
                     SP"
BASE COUNT          463 a          317 c          226 g          394 t
ORIGIN      
        1 aatgccgctt tatggtgact cacaaaaatt caccacatcc ctcacaacca ccttattacg
       61 cccggtctct ttcgcctcgt aaagtgcgtt atcagccagt cgatagatct catttgggtt
      121 taacgcattt tcctgagtca caacagcgcc aatactaatc gtcacttttt gtggtatagc
      181 gtattcagga ttatcgccag ttaaacgctc aacattttcc cgaatccttt ccgctaaagc
      241 tttcgcacgt tcagtatcga tgtccgtcag caagacgcca aactcttcgc cgccgacgcg
      301 cgctaaaagg tcatctggtc gtatgctttt cccaatgata ttcaccactg tttttatcac
      361 ctgatcgcca accggatgcc ccctggtgtc gttgactttt ttgaagtggt cgatatccat
      421 aatcatgacg caataaggcg ttttttgggc tgatgctgat tgaactgtca gttcattaaa
      481 aaaataattt ctgttaaata tattggttaa gggatcgcga tgtgcaatgt tctttgttac
      541 tcgtagcgca ctgaatatat ggcacataaa tattaccata acggttaact tactgactac
      601 ttcaatagtg cgactaatat accaagtgga cacgctatac ctgctcataa ataacagaga
      661 gatattgtac agtacggcac aaaaagcaat caccgtcact ccattccaga tatcatagcg
      721 taaaccatta aagtatagat taaccgaaag caaggttaac cacatgaaaa tcattatggt
      781 aacatatgag gctttccaaa ccacctgacc attttcattg gttaactcgg caatgtgtaa
      841 attgtagctc tcataatgac tagaaagtat gtgagcaact atcggccccc caaaaacaaa
      901 aaacaaactt atgcacaaag tcattttttt ggaaaataaa ttgcgctgtt ttgtgttttc
      961 actaacttta ttcaccaatg ccagaaatat taatatgcac aaactcatct gacgaaacaa
     1021 ataatagatt gcaatgtcat tttggacaac actgcttgtc aaacgctcct caataatttg
     1081 ctgaatgata atgacggtta taacaaagta aatcaaacaa ctcagaaaag ccaaactaag
     1141 tacacagttt gaaaattgcc tacggtcata aatgaaatac aactgcataa aaataaatgc
     1201 aacagtatcg ataaaaaata aagcaatcat taccatcaga taggttgatc gtggaacaac
     1261 ttcctcaacg cctggctgat taaaccaact attcaccaaa accaaagcaa gcccaaacaa
     1321 taagctcact aatacagtac tactaattct caaatagtct ttttccataa agctacacca
     1381 atctgtaggt tgtagatccc
//
LOCUS       DAPOAV010000265         1380 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.275, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000265 DAPOAV010000000
VERSION     DAPOAV010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1380
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.275"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            196..588
                     /gene="ydeI"
                     /locus_tag="RN951_004679"
     CDS             196..588
                     /gene="ydeI"
                     /locus_tag="RN951_004679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdeI family stress tolerance OB fold protein"
                     /protein_id="HDX2529530.1"
                     /translation="MKFQAIVLASFLVMPYALADDQGGLKQDAAPPPPHAIEDGYRGT
                     DDAKKMTVDFAKTMHDGASVSLRGNLISHKGEDRYVFRDKSGEINVVIPAAVFDGREV
                     QPDQMINISGSLDKKSAPAVVRVTHLQK"
     gene            843..>1380
                     /gene="dgcZ"
                     /locus_tag="RN951_004680"
     CDS             843..>1380
                     /gene="dgcZ"
                     /locus_tag="RN951_004680"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcZ"
                     /protein_id="HDX2529531.1"
                     /translation="MIKKTTEIDAILLNLNKAIDAHYQWLVSMFHSVVARDASKPEIT
                     DNHSYGLCQFGRWIDHLGPLDNDELPYVRLMDSAHQHMHNCGRELMLAIVENHWQDAH
                     FDAFQEGLLSFTAALTDYKIYLLTIRSNMDVLTGLPGRRVLDESFDHQLRNAEPLNLY
                     LMLLDIDRFKLVNDTYGHL"
BASE COUNT          390 a          258 c          309 g          423 t
ORIGIN      
        1 taaatccgat tattctgaaa atatgtttaa gacttttcaa tcttcttaac tttagtgagt
       61 taaattctct gtatatttga cagctagttg gctgatttta aatgccttat aacaattggc
      121 aatattctta tttggcaatt ataaaaatag caaccagact taataagtca aaccaaacgc
      181 aattaaggag ttagtatgaa atttcaggcc attgtattag caagttttct tgtcatgcct
      241 tatgcgttgg cagatgacca gggcggttta aaacaggatg cagcgccacc gccgcctcat
      301 gcaatagaag atggctatcg cggaaccgat gatgcaaaaa aaatgaccgt tgatttcgca
      361 aaaaccatgc acgatggcgc ttcggtttca ctacgcggta atttgatttc tcacaaagga
      421 gaggaccgtt acgtttttcg cgataagagc ggtgaaatta atgtcgttat tcctgcggcc
      481 gtctttgatg gacgagaagt tcagccggac cagatgatca acattagtgg cagtctggat
      541 aagaaaagcg cgccggccgt cgttcgggtc actcatttgc agaaataaaa ataaattagc
      601 ctgatggcct gaactactgg gccattaggg tattgggtta tgctatttgt catcctttta
      661 tttacgataa tgcagaggta atttacagaa ttaaacactt ttttatccgc tgattttgtt
      721 ttaaatcaca atgttatctc agagatgact cataacttcg gatttctatg aaaatattga
      781 cgtaattttg cttttctctc gttagaatag cgcgcacaag gaactgtgaa aaaggagtgg
      841 caatgatcaa gaagacaacg gaaattgatg ccatcttgtt aaatctcaat aaggctatcg
      901 atgcccacta ccagtggctg gtgagtatgt ttcacagcgt ggtcgcgaga gatgccagta
      961 agccagaaat aacggataac cattcttatg gactgtgcca gtttggtcgg tggattgatc
     1021 atctggggcc actcgataac gatgaattac cttacgttcg gctaatggat tctgcccatc
     1081 aacatatgca taactgtggt cgggaattaa tgctggctat tgttgaaaat cactggcagg
     1141 acgcgcattt cgacgccttt caggaggggt tgctttcttt tactgcggca ttaaccgatt
     1201 acaaaattta tttgctgacg atccgtagca atatggatgt tttgacggga ttgccgggtc
     1261 gtcgggttct tgatgaatcc tttgatcatc agttacgcaa cgctgagcct ctgaatcttt
     1321 atttaatgtt gttggatatt gaccgattta aattggttaa tgatacctac gggcatttaa
//
LOCUS       DAPOAV010000266         1352 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.276, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000266 DAPOAV010000000
VERSION     DAPOAV010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1352
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.276"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..677
                     /locus_tag="RN951_004681"
     CDS             <1..677
                     /locus_tag="RN951_004681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529532.1"
                     /translation="LRRVQIYLIIPLSIALLVHLQVIPLEMVFRNIETSDKSINFKVI
                     AELAFMSYFIFILTILPGLIYLKMNPQHKLSKRISSAFVASLMILLVISTQITVLPVI
                     FTHSVIKLSGISDFKIHSYIIKTSEYPEEFFSNAVWGKKNIKPGEYYSVQAVSMFTTN
                     QFILLCPKDIIRFYRESWKFDLLNVDFDTNTRKKLQEEAAYCVPISAISVKRWDMPLQ
                     GSKPSN"
     gene            complement(903..1078)
                     /locus_tag="RN951_004682"
                     /pseudo
     CDS             complement(903..1078)
                     /locus_tag="RN951_004682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612254.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          420 a          258 c          259 g          415 t
ORIGIN      
        1 tgttgagacg tgttcagatc tatcttatca ttccgttgtc tattgcttta ctggtgcatc
       61 ttcaggtaat tccactggag atggttttta ggaatattga aacttcagat aagagtatta
      121 atttcaaagt gatagctgaa ctggctttca tgtcatattt tatttttatt ctgacaatac
      181 ttcccggcct catttatcta aaaatgaatc cacagcataa actttctaaa agaattagtt
      241 ctgcatttgt cgcatccttg atgatattat tagttatatc gactcaaata accgtattac
      301 cagtaatttt tacccattca gttattaagc tctcaggtat aagtgacttc aaaatacata
      361 gctacattat taaaacaagt gaatatccgg aggagttttt ttccaatgca gtatggggta
      421 aaaaaaatat aaaaccgggg gaatattact ctgtgcaggc tgtttctatg tttacgacaa
      481 accagtttat tctcctttgt cccaaggata ttataaggtt ttatcgggaa agctggaagt
      541 tcgacctgct taatgtagac ttcgatacaa ataccaggaa gaaactccag gaagaagcag
      601 catattgcgt accaatttct gcaatatctg taaaacgatg ggatatgcct cttcagggct
      661 cgaaaccctc aaattagaag gccgctcgtg cgactgtatt agatagtaat gcggtatgga
      721 aaaatagtga tggcaagatg aacttgactt ggctaatcaa ataccggcgt agtgattagg
      781 aaacagggct cggataacat tattgcgcgg ttcattgaac ctactgatga cgccggatat
      841 atagtcgtaa accgtttcga accagtactt atatcaccag gagagtccat atatgaccac
      901 cgtttacagt aaaaacggta tctgttttct gatccctcca gcgtcaaact accgttgtaa
      961 tggtgaggtc tggtgctatt gtaataattc agaatataat ctctgattta tttccgaacc
     1021 tcgcccttgc ctgcgtaacc atccgtcgcc cccatcctgt tttcagactg cggaaaaagg
     1081 caagttttta tccccccaca gagattcaat catatatcgc gtgttttgga agtgacagtt
     1141 cttattcctg agaatactgc atgtgcaaca cactcggcat ccatcgatac cacttttatc
     1201 tccaataggc aggataaaaa acaagactgt gaattaaagt aatcggcaaa tgaatgagtt
     1261 agaagatact gaaaatgaat caaggactaa ccccgtaggg aatgaaaata ataaaagaac
     1321 atcttgtttt tattttaatg aatgagcatg tt
//
LOCUS       DAPOAV010000267         1342 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.277, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000267 DAPOAV010000000
VERSION     DAPOAV010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1342
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.277"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            182..1326
                     /locus_tag="RN951_004683"
                     /pseudo
     CDS             182..1326
                     /locus_tag="RN951_004683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000027427.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
BASE COUNT          491 a          189 c          309 g          353 t
ORIGIN      
        1 tgaacaacac cagaaagaga aaaatataaa atacatacag aaagacatga gagcaaggga
       61 cggggcaggg caagatcatg aaaattgtga tgtaaatcac gattttcatc tttgctttaa
      121 cgcctacagg tgatcaaaat ttaacctttg gaataactaa aaagataaaa aaggacgcca
      181 ggtgagtatt caaagtttgc ttgattatat ttcagtgacc cctgatatac gacaacaagg
      241 aaaggttaaa cataaattat ctgctatttt gtttctcacc gtatgtgcag taattgcagg
      301 tgccgatgag tggcaggaaa ttgaagattt tggacatgaa agacttgaat ggctaaagaa
      361 atatggtgat tttgataatg gcattccggt cgatgacacc attgcacgcg ttgtgagtaa
      421 cattgacagt ttggcctttg aaaagatgtt tattgaatgg atgcaggagt gccatgaaat
      481 cactgatggt gaaattatag caatagatgg aaagaccata agaggctcct ttgataaggg
      541 aaaaagaaaa ggagcaatcc atatggtgag tgcattctcg aacgaaaatg gtgttgtact
      601 ggggcaggtg aaaacggaag ccaaaagtaa tgagattaca gccattccag agttgcttaa
      661 cctactgtat ttaaagaaaa atttgataac cattgatgct atgggctgtc agaaagatat
      721 ctcttcgaag atcaaagata aaaaagcaga ttatcttctg gcagtaaaag gcaatcaggg
      781 gaaattacat catgcattcg aggaaaaatt tcctgtaaat gtgttttcta attataaagg
      841 cgattcgttt agtacgcagg agataagtca tggaagaaaa gaaacacgtt tgcatattgt
      901 cagtaacgta acgcctgaac ttttgtgatt ttgaattcga atggaaggga ttaaaaaagc
      961 tttgtgtagc attgtcattc aggcagaaga aagaagataa atcagcagaa ggtgtaagca
     1021 tccgatatta tatttcatca aaggatatgg atgctaaaga atttgcacat gctatcagag
     1081 cgcactggct gatcgagcac agtcttcatt gggtgttaga tgtaaaaatg aatgaagatg
     1141 ccagccggat aagaagagga aacgcagcct aaataatatc tggaataaag aagatggcac
     1201 tgaatttatt aagagattgc aaagacatta agggtgaaga ggaaaagaaa gaaggctgcg
     1261 ttaaacacag ggaaagatca tcagaagttc actttttgta ctaaacaatt cgcattttat
     1321 gtttaaaaat tgagatattc ct
//
LOCUS       DAPOAV010000268         1337 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.278, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000268 DAPOAV010000000
VERSION     DAPOAV010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1337
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.278"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            56..1267
                     /gene="bluF"
                     /locus_tag="RN951_004684"
     CDS             56..1267
                     /gene="bluF"
                     /locus_tag="RN951_004684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="blue light-responsive regulator BluF"
                     /protein_id="HDX2529533.1"
                     /translation="MLTTLIYRSHIRDDEPVKKIEEMVSIANRRNMQSDVTGILLFNG
                     SHFFQLLEGPEEQVKMIYRAICQDPRHYNIVELLCDYAPARRFGKAGMELFDLRLHER
                     DDVLQAVFDKGTSKFQLTYDDRALQFFRTFVLATEQSTYFEIPAEDSWLFIADGSDKE
                     LDSCALSPTINDHFAFHPIVDPLSRRIIAFEAIVQKNEDSPSAIAVGQRKDGEIYTAD
                     LKSKALAFTMAHALELGDKMISINLLPMTLVNEPDAVSFLLNEIKANALVPEQIIVEF
                     TESEVISRFDEFAEAIKSLKAAGISVAIDHFGAGFAGLLLLSRFQPDRIKISQELITN
                     VHKSGPRQAIIQAIIKCCTSLEIQVSAMGVATPEEWMWLESAGIEMFQGDLFAKAKLN
                     GIPSIAWPEKK"
BASE COUNT          380 a          285 c          287 g          385 t
ORIGIN      
        1 gaagatatgt ctgttaccgt cttactctcg cctcacccat taccctggat tgttaatgct
       61 taccaccctt atttatcgta gccatatacg tgacgacgaa cctgtcaaaa aaatcgaaga
      121 aatggtttcg atagcaaatc gcaggaacat gcagtctgac gtaacaggga tcttactgtt
      181 taatggttct cattttttcc agcttctgga aggtccggaa gaacaggtta aaatgatata
      241 tcgggctata tgccaggatc cacggcacta taatattgtt gagctgctgt gcgattacgc
      301 gcctgctcgc cgttttggca aagcgggaat ggaattattt gatttgcgcc tgcacgagcg
      361 agatgacgtt ttacaggccg tattcgacaa aggcacatca aaatttcagc taacttatga
      421 tgacagagcg ctacaatttt ttcgtacttt tgtccttgca accgaacaat caacctattt
      481 cgagatccct gccgaagact cctggctttt tatcgctgac ggatctgata aagaacttga
      541 ttcctgtgcc ctttcaccaa ctataaacga ccactttgcc tttcatccta ttgtcgatcc
      601 cttatcgcgg cggataatcg cttttgaagc cattgtgcaa aaaaatgaag atagcccatc
      661 agccatagcg gttgggcagc gtaaagacgg ggaaatctac acagcggatc tcaaaagtaa
      721 ggcgcttgca ttcacgatgg cacacgcact tgagctcggt gataaaatga tttcaatcaa
      781 tctattacct atgaccctgg ttaacgaacc tgacgcagtc tcttttttac ttaatgaaat
      841 aaaggccaat gctctggtgc ctgaacaaat catcgttgaa tttactgaaa gtgaagtcat
      901 atctcggttt gatgagtttg ccgaagcgat taaatcgcta aaggctgctg gtatcagtgt
      961 agcaattgat cattttggcg caggttttgc tggtttgtta ctcctgtcac gcttccagcc
     1021 tgacagaatt aaaatcagtc aggaattgat taccaatgtt cataaaagtg ggccacggca
     1081 ggcaattatt caggcgatca taaaatgctg tacatcactt gaaattcaag tcagtgctat
     1141 gggcgtggca acaccagaag agtggatgtg gcttgaatcc gcaggaattg agatgtttca
     1201 gggagatctg tttgctaaag ctaaattgaa tggtatccct tccatagcgt ggccagagaa
     1261 aaaataattt tcagcacatt ctttcacatg atttcagtaa atcatcgtga aaatgaatac
     1321 gttacgttta aatttaa
//
LOCUS       DAPOAV010000269         1324 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.279, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000269 DAPOAV010000000
VERSION     DAPOAV010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1324
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.279"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            175..669
                     /locus_tag="RN951_004685"
     CDS             175..669
                     /locus_tag="RN951_004685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529534.1"
                     /translation="MLGESQGQSKLIAFVAMPFSEKTSNYPHGYFDEVLKHLITPSAV
                     KAGFNAKTAKKAGSEVIQSTIVNDLDAADLVIVDLTEHNPNVLFELGMRIAFSKPVCL
                     IRAKGTAPIFDIDHMLRVYDYNPCLWPSTLESDIPQLSEHIKETWINRRERSYLDILR
                     ENKS"
     gene            complement(689..844)
                     /locus_tag="RN951_004686"
                     /pseudo
     CDS             complement(689..844)
                     /locus_tag="RN951_004686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001395480.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          412 a          248 c          277 g          387 t
ORIGIN      
        1 gaatatttaa agaatactct aaaaactgaa ttcggtatag atgatcaatt acaagacgac
       61 ttttataact tatatcaaca aaacctcaaa tacgttcgag aaaaagtcgc tagagaagat
      121 agcattagta ctaactcagt taatgacaaa actgccacag ctagtagttc cattatgctc
      181 ggtgaatctc aagggcaaag taaacttatt gcatttgttg ctatgccttt ttcagaaaaa
      241 acgtctaact acccgcatgg ttattttgat gaagtactta aacatctcat tacgccttct
      301 gcggtgaagg ctggatttaa tgctaagacg gcaaaaaaag cagggagtga agttattcaa
      361 tctacgattg tcaacgatct tgatgctgct gatcttgtga tagttgatct aactgaacac
      421 aatccaaatg tgctttttga attaggtatg aggattgcct ttagtaaacc tgtctgtttg
      481 atcagagcaa aaggtactgc acctatattt gatatagacc acatgttaag agtctatgat
      541 tataatcctt gcttatggcc ttctacgcta gaaagcgata ttccacaatt gtcagagcat
      601 ataaaagaaa catggataaa taggagagag cgttcatacc tcgatattct tagagaaaat
      661 aaaagctaaa tagttgcgcg gaataacgct actcttttgc cagcccatgt tgacctccgg
      721 aaaacgggct ggcggtttcc ataaaatggt gaactttttt tagcaactgc cacattgaac
      781 ggcactgatg attccgggtt attgtgtcat gtagcgcctg tcataaccgc tcaacgtggt
      841 tcacagtaaa catcccgtat aaccgggtca cggagatcag tcaggggaaa tggggctgaa
      901 attaatctct gtttgttggg caatacgccg ttcgccacag cgataaacag atggagcgag
      961 ctatgtcggc atatgggcta attgcagggc cagttgatta ataacaaaaa tcccgcgtaa
     1021 gtttccttaa gcgggatttt ctaaatttgg ctcccctgac tgggatcgcc attgccagta
     1081 actggctaat aagtaagcta aacctgaatt gctagtccgt caagaccacc agaatgacca
     1141 ccattaaacg ctgtactgtg gatcacgtgg atgtattgct ctgtgaattc acggagctaa
     1201 attgatataa aaaattagtc gaatattact aacatcatgg ccacaatgat cattgtggct
     1261 gattgtttat ggtatgagat ttttaattat gacataggta gtgttaataa gttcttgctg
     1321 tttt
//
LOCUS       DAPOAV010000270         1322 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.280, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000270 DAPOAV010000000
VERSION     DAPOAV010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1322
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.280"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..338)
                     /locus_tag="RN951_004687"
     CDS             complement(<1..338)
                     /locus_tag="RN951_004687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1398 family protein"
                     /protein_id="HDX2529535.1"
                     /translation="MDQVVVFQKMFEQVRKEQNFSWFYSELKHHRIAHYIYYLATDNI
                     RIITHDDTVLLLRGTRNLLKVSTTKNPAKIKEAALLHICGKSTFREYCSTLAGAGVFR
                     WVTDVNHNKR"
     gene            complement(559..1290)
                     /gene="bluR"
                     /locus_tag="RN951_004688"
     CDS             complement(559..1290)
                     /gene="bluR"
                     /locus_tag="RN951_004688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor BluR"
                     /protein_id="HDX2529536.1"
                     /translation="MAYYSIGDVAERCGINPVTLRAWQRRYGLLKPQRSEGGHRLFDE
                     EDIQRIEEIKRWISNGVPVGKVKALLETTSQDTEDDWSRLQEEMMSILRMANPAKLRA
                     RIISLGREYPVDQLINHVYLPVRQRLVLDHNTSRIMSSMFDGALIEYAATSLFEMRRK
                     PGKEAILMAWNVEERARLWLEAWRLSLSGWHISVLADPIESPRPELFPTQTLIVWTGM
                     APTRRQNELLQHWGEQGYKVIFHAP"
BASE COUNT          336 a          307 c          299 g          380 t
ORIGIN      
        1 ctgcgtttgt tatgattaac atcagtaacc caccggaaaa cgcccgcgcc tgccagtgtt
       61 gaacagtatt cccgaaatgt agattttccg caaatatgaa gcaatgcggc ctcttttatt
      121 ttagcagggt tcttggtcgt actaactttt aacaggttcc tggttcctct taataacaaa
      181 accgtatcat cgtgagtaat aattctgatg ttatccgtag ccagataata aatgtaatgt
      241 gcaatacggt gatgttttaa ttctgaataa aaccaggaga agttttgctc ttttctcact
      301 tgctcaaaca tcttttgaaa aacaacgacc tgatccatca ggataataac ctcttgttag
      361 ttgtgagact gcgtagtgtg cacgatcggt tttaccactt caatctggtc tgtcctttgg
      421 ctgtgatatg tacagagtgt gatagaggga atatctgaat tctcccggtg agcattttgc
      481 aacggaccag ctccggtaca aacgctgttg tgggttcaga ttataacatt ctgtctaagg
      541 ggcgggataa aggtgaaatt agggggcatg aaagatgact ttataacctt gctcacccca
      601 gtgttgtaaa agttcgtttt gccttctcgt tggtgccatg cctgtccaga caatcaatgt
      661 ttgcgtcggg aacagttccg ggcgcggcga ttcaatggga tcagcaagaa cagaaatgtg
      721 ccatcctgac aatgataaac gccatgcttc cagccacaat cgtgctctct cttcaacatt
      781 ccacgccatc agaatggctt ctttaccggg cttacggcgc atttcgaaaa gcgaggttgc
      841 tgcgtattca attaatgcgc cgtcaaacat actgctcata atgcgggagg tgttgtgatc
      901 aagcacgaga cgctggcgaa caggaaggta aacatgatta atcaattgat ctactgggta
      961 ctctcgaccc agtgaaataa ttctcgcgcg tagtttggca ggattagcca tgcgaagaat
     1021 tgacatcatc tcttcttgca ggcggctcca gtcatcttcc gtatcctggc tggtggtttc
     1081 cagtaatgct ttaactttgc ctacagggac gccattactt atccaacgct tgatctcttc
     1141 gatgcgttgt atgtcttctt catcaaagag tcggtgtccg ccttcactgc gctgtggttt
     1201 taacaaaccg tagcggcgtt gccaggcccg gagagtgaca ggattaatcc cgcaacgttc
     1261 agcaacatca ccaatgctgt aataagccac aattcctcct tgcggtcaca aatctccgtc
     1321 gc
//
LOCUS       DAPOAV010000271         1288 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.282, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000271 DAPOAV010000000
VERSION     DAPOAV010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1288
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.282"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..>1288
                     /locus_tag="RN951_004689"
     CDS             <1..>1288
                     /locus_tag="RN951_004689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001463032.1"
                     /note="cleaves origin of transfer and unwinds; oriT
                     relaxase; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="conjugative transfer relaxase/helicase TraI"
                     /protein_id="HDX2529537.1"
                     /translation="WQGGEQRPATIISEPDRNVRYDRLAGDFAASVKAGEESVAQVSG
                     VREQAILTQAIRSELKTQGVLGHPEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQWNP
                     ETRSHDRYVIDRVTAQSHSLTLRDAQGETQVVRISSLDSSWSLFRPEKMPVADGERLR
                     VTGKIPGLRVSGGDRLQVASVSEDAMTVVVPGRAEPATLPVADSPFTALKLENGWVET
                     PGHSVSDSATVFASVTQMAMDNATLNGLARSGRDVRLYSSLDETRTAEKLARHPSFTV
                     VSEQIKARAGETSLETAISLQKTGLHTPAQQAIHLALPVLESKNLAFSMVDLLTEAKS
                     FAAEGTGFTELGGEINAQIKRGDLLYVDVAKGYGTGLLVSRASYEAEKSILRHILEGK
                     EAVTPLMERVPGELMETLTSGQRAATRMILETSDRFT"
BASE COUNT          285 a          348 c          423 g          232 t
ORIGIN      
        1 gctggcaggg cggagaacag cgaccggcaa ccatcatcag tgaaccggac cggaatgtcc
       61 gctatgaccg gctggccgga gattttgcgg ccagcgtgaa agccggagaa gagagcgtgg
      121 cacaggtcag cggggtacgg gaacaggcca tactgacaca ggccattcgc agtgagctga
      181 aaacacaggg cgtgctcgga cacccggagg tgaccatgac cgccctgtca ccggtctggc
      241 tggacagccg gagccgttat ctgcgggata tgtaccgacc ggggatggtg atggagcagt
      301 ggaacccgga gacacgcagt catgaccgct atgttatcga ccgggtgacg gcgcagagtc
      361 acagcctgac cctgcgggat gcgcagggcg aaacgcaggt ggtgcgtatt tcctccctgg
      421 acagcagctg gtcgctgttc cggccggaaa aaatgccggt ggcagacggc gagcgactga
      481 gggtgacagg gaaaattccc ggactccgcg tctccggcgg tgaccgcctg caggtggcat
      541 ccgtcagtga agatgcgatg acggttgttg tgccggggcg ggctgaaccg gccaccctgc
      601 ctgtggctga ttcaccgttc acggcactga agctggagaa cggctgggtg gaaacgcccg
      661 ggcattccgt cagtgacagt gcgacggtgt ttgcctccgt cacacagatg gcaatggaca
      721 acgccaccct gaacggtctg gcccgcagcg gtcgtgatgt ccggctgtat tcctcactgg
      781 atgaaacccg tactgcggaa aaacttgccc gccatccctc ctttacggtg gtttctgagc
      841 agataaaggc gcgggccggt gagacatcgc tggaaaccgc tatcagtctg cagaaaaccg
      901 ggctgcacac gccggcacag caggccattc atctggccct tcctgtgctg gaaagtaaaa
      961 acctggcctt cagcatggtg gacctgctga cagaggcgaa gtcgtttgct gcagaaggaa
     1021 ccggttttac tgaactggga ggggaaatca atgcgcagat aaaacgcggt gacttactgt
     1081 atgtggatgt ggcaaaaggc tatggcacag gcctgctggt ttcccgtgcg tcgtatgagg
     1141 cagaaaaaag tattcttcgc catattctcg aaggtaagga ggcggtcacg ccgctgatgg
     1201 agagagtacc cggcgaactc atggagacgt taacgtcggg acagcgtgcc gccacccgta
     1261 tgatactgga aacgtccgac cgtttcac
//
LOCUS       DAPOAV010000272         1280 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.283, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000272 DAPOAV010000000
VERSION     DAPOAV010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1280
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.283"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(430..1062)
                     /locus_tag="RN951_004690"
     CDS             complement(430..1062)
                     /locus_tag="RN951_004690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdX family protein"
                     /protein_id="HDX2529538.1"
                     /translation="MKRLIMATMVTAILASSTVWAADNAPVAAQQQTQQVQQTQKTAA
                     AERISEQGLYAMRDVQVARLALFHGDPEKAKELTNEASALLSDDSTEWAKFAKPGKKT
                     NLNDDQYIVINASVGISESYVATPEKEAAIKIANEKMAKGDKKGAMEELRLAGVGVME
                     NQYLMPLKQTRNALADAQKLLDKKQYYEANLALKGAEDGIIVDSEALFVN"
BASE COUNT          341 a          265 c          265 g          409 t
ORIGIN      
        1 atcgtcgtag ctgcactcga tatttttaaa atcctgtatc aagtgctgaa aatcatttca
       61 tcgccacttc caattccttt ctgcatggta agtagtgagg acgaaaagaa gaatatgata
      121 aatattgatt cgtggtaatc agagagagtc gcgacatttg tgatgttatt cttacaactg
      181 taagaagcgc cggtgattta caagtaaggg tatgattacg ctttttaaag cgtaccataa
      241 aacataacat aataaatgat ttgtgatgac acgggattat tgggatttac tttgaggaag
      301 ataaaatgcg tgtttataga accgcgagcg ccaaataatt ttatgaccac aacctgtcgt
      361 attgtggtca taaaaaattg tcggctggag ggagttaaat cctttacctc aatatactgc
      421 ctgtcagcat tagttcacaa acagtgcttc gctgtcgacg atgattccat cttccgcacc
      481 tttaagcgcc aggtttgcct cgtagtattg ctttttatca agcagtttct gcgcatcagc
      541 aagtgcatta cgagtctgtt taagcggcat cagatattgg ttttccatta cgccaacacc
      601 ggccaggcga agttcttcca ttgcgccctt tttatcccct ttcgccattt tttcattggc
      661 aatttttatc gcggcttctt tttcgggagt tgctacataa ctctcagaaa ttccgacaga
      721 tgcattaatg acaatatatt ggtcatcatt gagattggtc tttttacctg gcttagcgaa
      781 ctttgcccat tcggtactgt catctgacag caaagcggaa gcttcattgg tcagttcttt
      841 tgccttttct ggatcgccat gaaacagagc caggcgcgct acctgcacgt cacgcatcgc
      901 atataaacct tgttcagaga tacgctctgc tgctgccgtt ttctgggttt gctgaacttg
      961 ctgagtttgc tgttgtgccg ctaccggtgc attatcagca gcccatacag ttgaagatgc
     1021 cagaattgct gtgaccatcg tagccataat taaacgtttc atacttacct cattctttaa
     1081 cagttttaga aaacgccgcc atcatattgg gtgagcatga aatgagaaat cagagagcaa
     1141 cggtcatttt gaaagggtta tcttacagtt gtagttatta tcgcaagaag tattttagtc
     1201 ttacaattgt aggaatctgc ttcctgtcgc agagaactat tcttatgtac cacaaagaga
     1261 tgtcatttat tatatcgatg
//
LOCUS       DAPOAV010000273         1254 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.284, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000273 DAPOAV010000000
VERSION     DAPOAV010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1254
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.284"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(4..843)
                     /gene="sul1"
                     /locus_tag="RN951_004691"
     CDS             complement(4..843)
                     /gene="sul1"
                     /locus_tag="RN951_004691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfonamide-resistant dihydropteroate synthase
                     Sul1"
                     /protein_id="HDX2529539.1"
                     /translation="MVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDV
                     GPAASHPDARPVSPADEIRRIAPLLDALSDQMHRVSIDSFQPETQRYALKRGVGYLND
                     IQGFPDPALYPDIAEADCRLVVMHSAQRDGIATRTGHLRPEDALDEIVRFFEARVSAL
                     RRSGVAADRLILDPGMGFFLSPAPETSLHVLSNLQKLKSALGLPLLVSVSRKSFLGAT
                     VGLPVKDLGPASLAAELHAIGNGADYVRTHAPGDLRSAITFSETLAKFRSRDARDRGL
                     DHA"
     gene            complement(837..1184)
                     /locus_tag="RN951_004692"
     CDS             complement(837..1184)
                     /locus_tag="RN951_004692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /protein_id="HDX2529540.1"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAF
                     YFLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLAR
                     SPSWKSLRRPTPW"
BASE COUNT          303 a          355 c          359 g          237 t
ORIGIN      
        1 atgctaggca tgatctaacc ctcggtctct ggcgtcgcga ctgcgaaatt tcgcgagggt
       61 ttccgagaag gtgattgcgc ttcgcagatc tccaggcgcg tgggtgcgga cgtagtcagc
      121 gccattgccg atcgcgtgaa gttccgccgc aaggctcgct ggacccagat cctttacagg
      181 aaggccaacg gtggcgccca agaaggattt ccgcgacacc gagaccaata gcggaagccc
      241 caacgccgac ttcagctttt gaaggttcga cagcacgtgc agcgatgttt ccggtgcggg
      301 gctcaagaaa aatcccatcc ccggatcgag gatgagccgg tcggcagcga ccccgctccg
      361 tcgcaaggcg gaaacccgcg cctcgaagaa ccgcacaatc tcgtcgagcg cgtcttcggg
      421 tcgaaggtga ccggtgcggg tggcgatgcc atcccgctgc gctgagtgca taaccaccag
      481 cctgcagtcc gcctcagcaa tatcgggata gagcgcaggg tcaggaaatc cttggatatc
      541 gttcaggtag cccacgccgc gcttgagcgc atagcgctgg gtttccggtt ggaagctgtc
      601 gattgaaaca cggtgcatct gatcggacag ggcgtctaag agcggcgcaa tacgtctgat
      661 ctcatcggcc ggcgatacag gcctcgcgtc cggatggctg gcggccggtc cgacatccac
      721 gacgtctgat ccgactcgca gcatttcgat cgccgcggtg acagcgccgg cggggtctag
      781 ccgccggctc tcatcgaaga aggagtcctc ggtgagattc agaatgccga acaccgtcac
      841 catggcgtcg gcctccgcag cgacttccac gatggggatc gggcgagcaa aaaggcagca
      901 attatgagcc ccatacctac aaagccccac gcatcaagct tttgcccatg aagcaaccag
      961 gcaatggctg taattatgac gacgccgagt cccgaccaga ctgcataagc aacaccgaca
     1021 gggatggatt tcagaaccag agaaagaaaa taaaatgcga tgccataacc gattatgaca
     1081 acggcggaag gggcaagctt agtaaagccc tcgctagatt ttaatgcgga tgttgcgatt
     1141 acttcgccaa ctattgcgat aacaagaaaa agccagcctt tcatgatata tctcccaatt
     1201 tgtgtagggc ttattatgca cgcttaaaaa taataaaagc agacttgacc tgat
//
LOCUS       DAPOAV010000274         1247 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.285, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000274 DAPOAV010000000
VERSION     DAPOAV010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1247
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.285"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..1247
                     /locus_tag="RN951_004693"
     rRNA            <1..1247
                     /locus_tag="RN951_004693"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          312 a          290 c          392 g          253 t
ORIGIN      
        1 ctgagaggat gaccagccac actggaactg agacacggtc cagactccta cgggaggcag
       61 cagtggggaa tattgcacaa tgggcgcaag cctgatgcag ccatgccgcg tgtatgaaga
      121 aggccttcgg gttgtaaagt actttcagcg gggaggaagg gagtaaagtt aatacctttg
      181 ctcattgacg ttacccgcag aagaagcacc ggctaactcc gtgccagcag ccgcggtaat
      241 acggagggtg caagcgttaa tcggaattac tgggcgtaaa gcgcacgcag gcggtttgtt
      301 aagtcagatg tgaaatcccc gggctcaacc tgggaactgc atctgatact ggcaagcttg
      361 agtctcgtag aggggggtag aattccaggt gtagcggtga aatgcgtaga gatctggagg
      421 aataccggtg gcgaaggcgg ccccctggac gaagactgac gctcaggtgc gaaagcgtgg
      481 ggagcaaaca ggattagata ccctggtagt ccacgccgta aacgatgtcg acttggaggt
      541 tgtgcccttg aggcgtggct tccggagcta acgcgttaag tcgaccgcct ggggagtacg
      601 gccgcaaggt taaaactcaa atgaattgac gggggcccgc acaagcggtg gagcatgtgg
      661 tttaattcga tgcaacgcga agaaccttac ctggtcttga catccacgga agttttcaga
      721 gatgagaatg tgccttcggg aaccgtgaga caggtgctgc atggctgtcg tcagctcgtg
      781 ttgtgaaatg ttgggttaag tcccgcaacg agcgcaaccc ttatcctttg ttgccagcgg
      841 tccggccggg aactcaaagg agactgccag tgataaactg gaggaaggtg gggatgacgt
      901 caagtcatca tggcccttac gaccagggct acacacgtgc tacaatggcg catacaaaga
      961 gaagcgacct cgcgagagca agcggacctc ataaagtgcg tcgtagtccg gattggagtc
     1021 tgcaactcga ctccatgaag tcggaatcgc tagtaatcgt ggatcagaat gccacggtga
     1081 atacgttccc gggccttgta cacaccgccc gtcacaccat gggagtgggt tgcaaaagaa
     1141 gtaggtagct taaccttcgg gagggcgctt accactttgt gattcatgac tggggtgaag
     1201 tcgtaacaag gtaaccgtag gggaacctgc ggttggatca cctcctt
//
LOCUS       DAPOAV010000275         1241 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.286, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000275 DAPOAV010000000
VERSION     DAPOAV010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1241
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.286"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            173..1153
                     /locus_tag="RN951_004694"
     CDS             173..1153
                     /locus_tag="RN951_004694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110-like element IS621 family transposase"
                     /protein_id="HDX2529541.1"
                     /translation="MEHELHYIGIDTAKEKLDVDVLRPDGRHRTKKFANTTKGHDELV
                     SWLKGHKIDHAHICIEATGTYMEPVAECLYDAGYIVSVINPALGKAFAQSEGLRNKTD
                     TVDARMLAEFCRQKRPAAWEAPHPLERALRALVVRHQALTDMHTQELNRTETAREVQR
                     PSIDAHLLWLEAELKRLEKQIKDLTDDDPDMKHRRKLLESIPGIGEKTSAVLLAYIGL
                     KDRFAHARQFAAFAGLTPRRYESGSSVRGASRMSKAGHVSLRRALYMPAMVATSKTEW
                     GRAFRDRLAANGKKGKVILGAMMRKLAQVAYGVLKSGVPFDASRHNPVAA"
BASE COUNT          305 a          304 c          369 g          263 t
ORIGIN      
        1 agagaaaatc ggccagtttt ctctgcctgc agtccgcatg ccgtatcggg ccttgggttc
       61 taacctgttg cgtagattta tgcagcggac tgcctttctc ccaaagtgat aaaccggaca
      121 gtatcatgga ccggttttcc cggtaatccg tatttgcaag gttggtttca ctatggaaca
      181 tgaacttcat tatatcggta tcgacaccgc taaagagaaa ctggatgtcg atgtgttgcg
      241 tcctgatggt cgtcatcgca ccaaaaaatt cgctaacacc actaaagggc acgatgagct
      301 ggtgagctgg ctgaaaggtc acaagattga ccatgcgcat atctgcatcg aagcgaccgg
      361 cacctatatg gaacctgtcg ctgagtgcct ttacgatgct ggctacatag tgtcagtcat
      421 taatcctgcg ctgggtaaag ctttcgctca gagtgaagga ctgcgtaaca agactgatac
      481 cgtggatgcg cgcatgctgg cagagttctg tcgtcagaag cgccctgcag cctgggaagc
      541 gcctcacccg cttgaacgcg cgttgcgtgc cctggtagtc cgccaccagg cgctgacaga
      601 tatgcacacg caggaactga atcgcactga aacggcgcgg gaagtccaga gaccgagcat
      661 tgatgctcac cttctgtggc ttgaagcaga gctgaagcgt cttgagaagc agataaaaga
      721 cctgacagac gatgatccgg atatgaaaca ccgcaggaaa ctgctggaaa gcatcccggg
      781 tatcggagag aaaacatctg cggtattgct ggcttatatc ggtctgaagg accgcttcgc
      841 ccatgccaga cagttcgccg cttttgcggg tctgacacca cggcgttatg aatcaggtag
      901 cagtgtgaga ggggcgagcc ggatgagtaa ggccggacat gtgtcgcttc gcagggcgtt
      961 gtatatgccc gcaatggtag ccaccagtaa gactgagtgg ggacgggcgt tccgcgaccg
     1021 tctggcggct aatggcaaga aaggaaaggt gattctcggc gcgatgatgc gcaagctggc
     1081 acaggtggcg tatggagtgc tgaagtcagg cgtgccgttc gatgcgtcac ggcataatcc
     1141 ggtagcggcg taaaaatcgc ggaagggatg aaaaaaacag cgcctgacgg cgctgtgtct
     1201 ggcatgcctg caatccggga aaccggacca ggaaaaaact t
//
LOCUS       DAPOAV010000276         1232 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.287, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000276 DAPOAV010000000
VERSION     DAPOAV010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1232
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.287"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..125)
                     /locus_tag="RN951_004695"
     CDS             complement(<1..125)
                     /locus_tag="RN951_004695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide 1,3-galactosyltransferase"
                     /protein_id="HDX2529542.1"
                     /translation="MQQVFFQETEFLNSVIDYNHKIEAENLCLDIAYGTDKNFLFG"
     gene            complement(125..1204)
                     /gene="waaB"
                     /locus_tag="RN951_004696"
                     /gene_synonym="rfaB"
     CDS             complement(125..1204)
                     /gene="waaB"
                     /locus_tag="RN951_004696"
                     /gene_synonym="rfaB"
                     /EC_number="2.4.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418085.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide 1,6-galactosyltransferase"
                     /protein_id="HDX2529543.1"
                     /translation="MKIAFIGEAVSGFGGMETVIRDVITTFRQQHIQSEIFFFCRNDK
                     MDKGWLEGIKYSCSFSNIRLGFLRRAKHIHALSKWLHDYQPDVVICIDVISCLYAAKA
                     RKKSGIDVPVFSWPHFSLDHKKHAEYITCADYHLAISSGIKQQMISRGVPESTINVIF
                     NPVEAKNSVIPAPGEGETATFIYVGRMKFEGQKRVKDLLDGLSQVQGDWKLHVLGDGS
                     DFEKCQAYGRELNIDDRIVWYGWQQHPWKLVQQDIKKVSALLLTSSFEGFPMTLLEAL
                     SWGIPCISADCVSGPVDIIQPDVNGHLYQPGDMTGFVALLNKYIAGEIHIAHEKIPAS
                     IDKFYQPKYYDRLQKIIISVISRRK"
BASE COUNT          393 a          268 c          213 g          358 t
ORIGIN      
        1 ccaaaaagaa aatttttgtc agtcccataa gcaatatcca gacaaagatt ttctgcttct
       61 attttatgat tataatcaat aaccgaattg agaaactcag tctcctggaa aaaaacctgc
      121 tgcattattt cctccgggaa ataacagaaa taattatctt ttgcaatctg tcgtaatatt
      181 tcggttgata aaatttatcg atcgacgccg gaattttttc atgtgcgatg tgaatttcac
      241 cggctatgta tttattgaga agagcaacaa aaccggtcat atcccccggt tgatataaat
      301 gaccattaac atcaggctga atgatatcaa caggcccgga gacacaatct gcactgatac
      361 aagggatccc ccacgacaag gcttcaagta gagtcattgg gaaaccttca aaagatgacg
      421 tgagtaataa tgcactcact tttttaatat cttgctgaac taatttccag ggatgttgtt
      481 gccaaccata ccagacaatt cgatcatcaa tatttaattc tctaccataa gcctggcatt
      541 tttcgaaatc ggagccatct cccaatacat gaagtttcca gtcaccttgc acttgtgata
      601 agccatcaag cagatctttt acgcgctttt ggccttcaaa tttcatgcgc ccaacataaa
      661 tgaatgttgc cgtttcgcct tccccgggtg caggaatgac tgaatttttc gcctcaacgg
      721 gattaaaaat aacgtttatt gtcgattctg gtacaccccg gctaatcatt tgctgtttaa
      781 taccagagct gatggctaaa tgatagtcgg cacaggtgat atattcggca tgttttttat
      841 gatctaaaga aaaatgcggc catgaaaata caggtacatc aatccccgat tttttacgag
      901 ctttggccgc atacaaacac gagatcacgt caatacaaat aacaacatct ggctgataat
      961 catgaagcca tttgcttaaa gcatgaatat gtttcgcgcg acgcaaaaaa cctaagcgaa
     1021 tattggaaaa tgaacacgag tacttaatac cttccagcca tcccttatcc attttgtcat
     1081 tacgacaaaa gaaaaaaatt tcactttgga tatgttgttg cctgaaggta gtaataacat
     1141 cacgaatgac tgtttccatg ccgccaaatc cagaaacagc ttcgccaata aaggctattt
     1201 tcataatttc attccagcta aatctttaag cc
//
LOCUS       DAPOAV010000277         1199 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.288, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000277 DAPOAV010000000
VERSION     DAPOAV010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1199
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.288"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..>1199
                     /locus_tag="RN951_004697"
     CDS             <1..>1199
                     /locus_tag="RN951_004697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001335741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter domain-containing protein"
                     /protein_id="HDX2529544.1"
                     /translation="VTCPADPGKLSPEELKRLPSECSPLVEQNLMPWLSTGAAALITA
                     LAVVELNDDDDHHHRNNSPLPPTPPDDESDDTPVPPTPGGDEIIPDDPDDTPTPPKPV
                     SFNNDVILDKTEKTLTIRDSVFTYTENADGTISLQDSNGRKATINLWQIDEANNTVAL
                     EGVSADGATKWQYNHNGELVITGDNATVNNNGKTTVDGKDSTGTEINGNNGKVIQDGD
                     LDVSGGGHGIDITGDSATVDNKGTMTVTDPESMGIQIDGDKAIVNNEGESTITNGGTG
                     TQINGDDATANNNGKTTVDGKDSTGTEINGNNGKVIQDGDLDVSGGGHGIDITGDSAT
                     VDNKGTMTVTDPESIGIQVDGDQAVVNNEGESAITNGGTGTQINGDDATANNNGKTTV
                     DGKDSTGT"
BASE COUNT          352 a          312 c          308 g          227 t
ORIGIN      
        1 gtgacttgtc cggcagaccc aggaaaactc agtccggaag agcttaaacg cttaccctct
       61 gaatgctctc ctttagtcga acaaaacctg atgccatggc tttccacagg cgctgctgcg
      121 ttaatcacgg ccttagccgt agtggaacta aacgacgatg atgatcatca tcatcgcaac
      181 aattctccac tcccaccgac accccctgat gatgaatcag acgacactcc agttccccca
      241 actcctggcg gagatgagat aataccggac gatccggatg atacgcctac acctcccaaa
      301 ccggtttcgt ttaataatga cgttattctc gataaaacag aaaaaacgtt aactattcgc
      361 gattcagttt ttacttatac cgagaatgct gacgggacta tatctctgca agatagcaat
      421 ggtcgtaagg caacgattaa tctttggcag attgatgaag cgaataacac tgttgccctt
      481 gaaggggtga gcgcagatgg cgcaacgaag tggcaatata atcacaacgg tgagcttgtt
      541 attacgggtg ataatgccac agtaaacaac aatggcaaaa ccaccgttga cggtaaagat
      601 tccaccggta cggaaatcaa cggtaataac gggaaagtga ttcaggacgg cgatctggat
      661 gtcagcggcg gcggtcacgg tattgatatc accggtgaca gcgcgacggt ggataacaag
      721 ggcaccatga ccgtcaccga tccggagtcc atgggtatcc agatcgacgg tgacaaggcc
      781 atcgtcaata acgaaggcga gagcaccatc accaacggtg gcaccggcac ccagattaat
      841 ggtgatgacg ccacggcaaa caacaacggc aaaaccaccg ttgacggcaa ggattccacc
      901 ggtacggaaa tcaacggtaa taacggaaaa gttattcagg acggcgatct ggatgtcagc
      961 ggcggcggtc acggtattga tatcaccggc gacagcgcaa cggtggataa caagggcacc
     1021 atgaccgtca ccgatccgga gtccatcggt atccaggttg acggcgacca ggcggttgtt
     1081 aacaacgaag gcgagagcgc catcaccaac ggtggcaccg gcacgcagat taacggtgat
     1141 gacgccacgg caaacaacaa cggcaaaacc accgttgacg gcaaggattc caccggtac
//
LOCUS       DAPOAV010000278         1194 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.289, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000278 DAPOAV010000000
VERSION     DAPOAV010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1194)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1194)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1194
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.289"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(186..>1194)
                     /locus_tag="RN951_004698"
     CDS             complement(186..>1194)
                     /locus_tag="RN951_004698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HDX2529545.1"
                     /translation="ALAELVNHQYRHAFAAHWGDGTTSSSDGQRFRAGGRGESTGHVN
                     PKYGSEPGRLFYTHISDQYAPFSTRVVNVGVRDSTYVLDGLLYHESDLRIEEHYTDTA
                     GFTDHVFALMHLLGFRFAPRIRDLGETKLYVPQGVQAYPTLRPLIGGTLNIKHVRAHW
                     DDILRLASSIKQGTVTASLMLRKLGSYPRQNGLAVALRELGRIERTLFILDWLQSVEL
                     RRRVHAGLNKGEARNSLARAVFFNRLGEIRDRSFEQQRYRASGLNLVTAAIVLWNTVY
                     LERATQGLVEAGKPVDGELLQFLSPLGWEHINLTGDYVWRQSRRLEDGKFRPLRMPGK
                     P"
BASE COUNT          226 a          360 c          372 g          236 t
ORIGIN      
        1 ccatacttta ttatacaaaa ttgttccatc atacaacgtt agatatcctt ctctcaggcc
       61 ttcagatgca agtatggaat gcaacatagg aattgctgta aagtgatata aatccataaa
      121 taaccctatt ctgtctattt atattcattt taggggagcc cgcagaattc ggaaaaaatc
      181 gtacgctaag gttttccggg catccgtaag ggccgaaact tcccgtcttc cagtctgcgg
      241 ctctgccgcc agacgtaatc gccggttagg ttgatgtgct cccagcccag cggcgacagg
      301 aattgcagca gctcgccgtc caccggcttg ccggcctcga ccaacccctg ggtggcgcgt
      361 tccaggtaca ccgtgttcca cagcacgata gccgccgtca ccaggttgag gccgctggcc
      421 cggtagcgct gctgctcgaa gctccgatcc ctgatttccc caaggcggtt gaagaacacc
      481 gccctggcca gcgagttgcg cgcctcacct ttgttcaggc cggcatgcac gcggcggcgc
      541 agttcaacac tttgcagcca gtccaggatg aacagcgtgc gctcgatccg gcccagctcg
      601 cgcagggcca cggccagtcc gttctggcgc gggtagctgc cgagcttgcg cagcatcagc
      661 gaggcggtga cggtgccctg cttgatcgag ctggccaggc gcaggatgtc gtcccagtgg
      721 gcacgcacgt gcttgatgtt cagggtgccg ccgatcagcg ggcgcaacgt cgggtaggct
      781 tgcacgccct gcggcacgta cagcttggtt tcgccgaggt cgcggatgcg cggcgcgaag
      841 cggaagccta gcaggtgcat cagggcaaag acgtgatcgg tgaagccggc cgtgtcggtg
      901 tagtgctcct cgatccgcag gtcggactcg tggtacagca ggccgtcgag cacataggtg
      961 gaatcgcgga cgccgacatt caccacgcgg gtgctgaacg gcgcgtactg gtcggagata
     1021 tgggtataga acagccgtcc cggctcgcta ccgtacttcg ggttgacgtg cccggtgctc
     1081 tcgccccggc cacccgcgcg gaagcgctgg ccatcggagg atgaggtcgt gccgtcgccc
     1141 cagtgggcgg caaaggcgtg gcgatactgg tggttgacca gctcggccaa ggcc
//
LOCUS       DAPOAV010000279         1148 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.291, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000279 DAPOAV010000000
VERSION     DAPOAV010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1148
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.291"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..434
                     /gene="wzm"
                     /locus_tag="RN951_004699"
     CDS             <1..434
                     /gene="wzm"
                     /locus_tag="RN951_004699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_085452492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="O89/O101/O162 family O-antigen export ABC
                     transporter permease subunit"
                     /protein_id="HDX2529546.1"
                     /translation="FMMLCHNIVIVIGVLIIFNVFSLKNFPLFILGFMIVVVNLIWIA
                     TLFAVISVRFRDFPQMVMSFMQVVFYITPILFSGTMLAKYSLLLKLNPFAWFIEIIRS
                     PLVGKMPELYCYYNSIILACVGTVISLITFAKCRNRIAYWV"
     gene            441..>1148
                     /locus_tag="RN951_004700"
     CDS             441..>1148
                     /locus_tag="RN951_004700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000018742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDX2529547.1"
                     /translation="MSHLIDLKDVGVEFPIYDAKSRSFKSQVANLTRGVISSKKESST
                     VTVKSLDGLTFSLKEGDKLGLIGNNGAGKSTLLKLLAGIYEPTSGTIKRKGKIVPLLD
                     IALGMDDDSTGYQNIKLRGLLLGMTNAEIESKIEEIACFTELGDYLNLPIRVYSTGMR
                     VRLAFAVSTSVDPDVLLLDEIIGTGDASFLNKAKKRFQELQERAKVVVLSSHDNNVIL
                     KTCNKVLWLEGGKPKMIG"
BASE COUNT          340 a          186 c          245 g          377 t
ORIGIN      
        1 attttatgat gctttgccat aatatagtaa tagtgattgg tgtgttgatt atattcaacg
       61 tcttttcgtt gaagaatttc ccgcttttta tacttggatt tatgatcgta gttgttaatc
      121 tgatctggat tgcaacttta tttgcagtaa tttctgtacg ttttagagat tttccgcaaa
      181 tggtcatgag ttttatgcag gttgtctttt atataacgcc gatattattt tctggaacaa
      241 tgttggctaa atatagcttg ctgctgaagt taaacccatt tgcttggttt atcgagatta
      301 ttcgctcgcc tttagtaggg aaaatgcccg agttatactg ctattataat tctattatcc
      361 ttgcatgcgt aggaacagtt atctcactaa ttacatttgc aaaatgtaga aatcgcattg
      421 catattgggt gtaaattatt atgtctcatt tgattgactt aaaagatgtg ggtgtcgaat
      481 ttcccattta cgacgctaaa agtagatcgt ttaaatcgca ggtggctaac ttaacccgcg
      541 gtgttatttc ttcaaaaaaa gaaagcagca cggttacggt taaatcatta gacggtttaa
      601 cgtttagtct gaaagaaggt gataaactcg gacttattgg aaacaatggc gcgggaaaat
      661 ctacgctact gaagctgttg gctggtatct atgaaccaac ctccggcaca attaaaagaa
      721 agggtaagat agttccactg ttggatatcg ctctaggaat ggatgatgat tccacaggat
      781 accaaaatat aaaactacgc ggtttgttac ttggtatgac gaatgcagaa atcgaatcca
      841 aaatagaaga gatcgcttgc ttcacagaac taggtgatta cctgaatcta ccaattcgtg
      901 tctactctac cgggatgcgc gtgagattag catttgcagt atcaacttca gttgatccag
      961 atgtactttt actcgacgaa attattggga ctggtgatgc ttctttctta aataaagcaa
     1021 agaaaagatt ccaggagttg caggagaggg caaaggttgt tgtgctatct tcccatgaca
     1081 acaatgtcat tctgaaaact tgtaataaag ttctgtggtt agaaggtggt aaaccaaaga
     1141 tgattgga
//
LOCUS       DAPOAV010000280         1146 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.292, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000280 DAPOAV010000000
VERSION     DAPOAV010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1146
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.292"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            43..387
                     /gene="tdcR"
                     /locus_tag="RN951_004701"
     CDS             43..387
                     /gene="tdcR"
                     /locus_tag="RN951_004701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417589.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator TdcR"
                     /protein_id="HDX2529548.1"
                     /translation="MTGITIFYGDNIIRYVVNTKKGLRPYFKQLPDNYQAKFELNLMS
                     KFSNFIINKPFSVINNAACHIFSRYLLENKHLFYQYFKISNTCIDHLEQLINVNFFSS
                     DRTSFCECNRFP"
     gene            643..>1146
                     /locus_tag="RN951_004702"
     CDS             643..>1146
                     /locus_tag="RN951_004702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417590.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529549.1"
                     /translation="MKGFPIAHIFHPSIPPMHAVVNNHNRNIDYWTVKRKFAEIVSTN
                     DVNKIYSISNELRRVLSAITALNFYHGDVPSVMIRIQPENMSPFIIDISTGEHDDYII
                     QTLDVGTFAPFGEQCTCSAVNKKELECIKETISKYCAKFTRKEAILTPLVHFNKTSIT
                     SDCWQILF"
BASE COUNT          384 a          206 c          204 g          352 t
ORIGIN      
        1 aagtataaaa atcagcataa accctgattt ttgtcaaaaa aaatgacggg gataaccata
       61 ttttatggcg ataacatcat tcgttatgtg gttaatacaa aaaaggggct gagaccatat
      121 ttcaagcaat taccggataa ttaccaggca aaatttgagt taaatttaat gagcaagttc
      181 tcaaatttta ttataaataa accattttca gtgataaata atgcggcatg tcacattttt
      241 tcacgctatt tgttggagaa caaacattta ttttatcaat attttaaaat ttcgaataca
      301 tgtattgatc atctcgaaca attgattaac gtcaactttt tctcttctga caggacgtca
      361 ttttgtgaat gcaatcgttt tccataaatt cttctcccct cataggcgac gaatagcatt
      421 ttgtgttgag gatcacaaaa cgaataattg ctgatcgccg cgataaggtc agacaaagac
      481 aacaagggaa attttcacag agcttttgat cggcgtaggc cacagaatgt tgcttcgttt
      541 actgtaacgc cgggtaaatg agcgtttttt gatagtgcga aagaaccctg cgaggaaaat
      601 aagcatctat tattgtttgt catgatgaca aggcaggcat caatgaaagg cttcccaatt
      661 gcgcatattt ttcacccttc aatcccgcca atgcacgcag tggttaacaa tcacaataga
      721 aatattgatt attggacggt aaaaagaaag tttgcagaaa ttgtctccac caatgacgtt
      781 aataaaattt acagtataag taatgaactg cggagagtat tatctgcaat aactgcattg
      841 aatttctatc atggcgatgt tccttctgtc atgatccgaa tccaaccgga aaatatgagt
      901 ccattcatta tagatatttc tacaggagaa catgatgatt atatcataca aacattagat
      961 gtaggcactt ttgcaccttt tggtgaacaa tgtacttgct cagccgtcaa taaaaaagag
     1021 ctggaatgta ttaaggagac gatttctaag tattgtgcaa aattcacccg aaaagaagcc
     1081 atcttaaccc cccttgtgca ctttaataaa accagcatta cttcagattg ttggcaaatt
     1141 ctcttt
//
LOCUS       DAPOAV010000281         1127 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.293, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000281 DAPOAV010000000
VERSION     DAPOAV010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1127
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.293"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..338
                     /locus_tag="RN951_004703"
     CDS             <1..338
                     /locus_tag="RN951_004703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YbbC/YhhH family protein"
                     /protein_id="HDX2529550.1"
                     /translation="FFILFACNETAVYGSDENIIFMRYVEKLHLDKYSVKNTVKTETM
                     AIQLAEIYVRYRYGERIAEEEKPYLITELPDSWVVEGAKLPYEVAGGVFIIEINKKNG
                     CVLNFLHSK"
     gene            338..1048
                     /locus_tag="RN951_004704"
     CDS             338..1048
                     /locus_tag="RN951_004704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308587.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HDX2529551.1"
                     /translation="MLALMDADGNIAWSGEYDEWGNQLNEENPHHLHQPYRLPGQQYD
                     KESGLYYNRNRYYDPLQGRYITQDPIGLEGGWSLYAYPLNPVNGIDPLGLSPADVALI
                     RRKDQLNHQRAWDILSDTYEDMKRLNLGGTDQFFHCMAFCRVSKLNNAGVSRSAKGLG
                     YEKEIRDYGLNLFGMYGRKVKLSHSEMIEDNKKDLAVNDHGLTCPSTTDCSDRCSDYI
                     NPEHKKTIKALQDAGYLK"
BASE COUNT          366 a          164 c          273 g          324 t
ORIGIN      
        1 cattttttat actatttgcc tgtaatgaga cagctgttta cggttctgat gaaaacatta
       61 tttttatgag gtatgtggaa aaattacatt tagataaata ctctgttaaa aatacggtaa
      121 aaactgaaac aatggcgata caattagctg aaatatatgt taggtatcgc tatggcgaac
      181 ggattgcaga agaagaaaaa ccatatttaa ttacggaact accagatagt tgggttgttg
      241 agggagcaaa gttaccttat gaagttgcgg gtggtgtatt tattatagaa attaataaga
      301 aaaatggatg tgttttgaat ttcctacata gtaaataatg ctggcgctga tggatgcgga
      361 tggaaacatt gcgtggagcg gggagtatga tgagtggggc aaccagctga atgaagagaa
      421 cccgcatcac ctgcaccagc cgtaccggct gccggggcag cagtatgata aggagtcggg
      481 gctgtactac aaccggaacc ggtactacga tccgttgcag gggcggtata tcactcagga
      541 cccgataggg ctggaggggg gatggagtct gtatgcgtat ccgctgaatc cggtgaatgg
      601 tattgatcca ttagggttaa gtcccgcaga tgtagcgcta ataagaagaa aagatcaact
      661 aaaccatcaa agagcatggg atatattatc tgatacttat gaagatatga agagattaaa
      721 tttaggtggg actgatcaat ttttccattg tatggcattt tgtcgagtgt ctaaattaaa
      781 taacgctggt gttagccgat cggcgaaagg gctgggttat gaaaaagaga ttagagatta
      841 cgggttaaat ctgttcggta tgtacggcag aaaagtaaag ctatcccatt ctgaaatgat
      901 tgaagataat aaaaaagact tggctgtaaa tgaccatggg ttgacatgtc catcaacaac
      961 agattgctca gatagatgta gtgattatat taatccagag cataaaaaaa cgataaaggc
     1021 tttacaagat gctggctatc tcaagtaatc tatcaaagat gataatattt atttttgcta
     1081 ttataatcat tgttgtttta tgcgtaatta cttatcttta tttatac
//
LOCUS       DAPOAV010000282         1127 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.294, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000282 DAPOAV010000000
VERSION     DAPOAV010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1127
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.294"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..834
                     /locus_tag="RN951_004705"
     CDS             <1..834
                     /locus_tag="RN951_004705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001704620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDX2529552.1"
                     /translation="FNLLDSLYVESVDTLTFKYQSIIKGLDRLFEGINLDSAFSLSEE
                     ERSYFEEKAKSLNALAQLGISVEIISHELEEMDSMVTRGLNSLPTSVKEHPGFSLALN
                     AHRSLTQQIRFLSPLKISGYQSRQRITGKNIMDYVLKFFGERFERQRITIEFSEEFKQ
                     IAITDIPSRIYPVFTNIINNAMYWVSLSNNRLIKIGFVNSLVIIANSGPAIDTDDIPR
                     LFELFYSKRANGHGVGLYLCRENLAVAHHKIWYSEPDEGDNYLIKDGANFVIQFNGVE
                     F"
     gene            836..>1127
                     /locus_tag="RN951_004706"
     CDS             836..>1127
                     /locus_tag="RN951_004706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529553.1"
                     /translation="MTVANYNSLVQKTFCENAIRSVVMIDDDFLTYSESIRALNNEVD
                     LDYNKIDSSKRAATLESFFQSKNMICDVDNGSVNFDVDRIRKSDLIIVDYHLD"
BASE COUNT          368 a          178 c          211 g          370 t
ORIGIN      
        1 tttaatttgc tcgatagttt atatgttgag tcagttgata ccctaacttt caaatatcaa
       61 tcaataataa aaggtctcga tagattattt gaaggtataa acttagattc agcattctca
      121 ttatctgaag aagaacgctc atattttgaa gaaaaagcta aaagtttaaa cgcgcttgca
      181 cagttaggta ttagtgttga gataatatct catgaacttg aagaaatgga ttctatggta
      241 accagaggac taaactctct tcctacttct gtaaaagaac accctggttt ttcattggcg
      301 ttaaatgctc acagatcgct tactcaacaa atacgtttct tatcaccttt gaaaatatca
      361 ggttatcaat ccaggcagag aataactgga aaaaatatca tggattatgt cctgaagttc
      421 tttggggagc gtttcgaacg gcaacgaata actattgaat ttagtgaaga gtttaagcaa
      481 atcgcaataa cagatatacc atcaaggatc tatcctgttt ttactaatat tatcaacaat
      541 gcaatgtatt gggtcagtct gtcaaataat aggctcataa agattggttt tgtgaattct
      601 ttggttatca tagcaaattc tggtccggca attgataccg atgatatccc gcgactattt
      661 gaactatttt atagcaaaag agcaaatgga catggggtag gtctgtatct atgtcgagaa
      721 aaccttgctg ttgcacatca taaaatatgg tattcagaac ctgatgaagg cgataactat
      781 ttaataaaag atggcgctaa ttttgtgatc cagttcaatg gagtggagtt ctaatatgac
      841 agtggcaaat tataattctc ttgtccagaa aactttctgc gaaaatgcaa ttcgttccgt
      901 tgtcatgatt gatgacgatt ttctgacgta ttctgaatca atcagggcgt tgaataacga
      961 agttgattta gactacaaca aaattgactc atctaaacga gccgctactc ttgagagctt
     1021 ttttcaatct aaaaatatga tttgtgatgt tgacaatggt tctgttaatt tcgatgtgga
     1081 tcggattaga aaatcagatc ttattattgt agattatcat cttgata
//
LOCUS       DAPOAV010000283         1112 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.295, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000283 DAPOAV010000000
VERSION     DAPOAV010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1112
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.295"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..905
                     /locus_tag="RN951_004707"
     CDS             <1..905
                     /locus_tag="RN951_004707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDX2529554.1"
                     /translation="ALDVRLPEQFSIIGKLRAHYPVATLCHVFGVHRSSYRYWKNRPE
                     KPDGRRAVLRSQVLELHGISHGSAGARSIATMATRRGYQMGRWLAGRLMKELGLVSCQ
                     QPTHRYKRGGHEHVAIPNYLERQFAVTEPNQVWCGDVTYIWTGKRWAYLAVVLDLFAR
                     KPVGWAMSFSPDSRLTMKALEMAWETRGKPGGVMFHSDQGSHYTSRQFRQLLWRYQIT
                     QSMSRRGNCWDNSPMERFFRSLKNEWMPVVGYVSFSEAAHAITDYIVGYYSALRPHEY
                     NGGLPPNESENRYWKNSNSVASFC"
BASE COUNT          275 a          298 c          297 g          242 t
ORIGIN      
        1 gcgctcttga tgtcagactc cctgaacagt tctcgataat cgggaaactc agagcgcatt
       61 atcctgtggc cacactctgc catgtgttcg gggttcatcg cagcagctac agatactgga
      121 aaaaccgtcc tgaaaaacca gacggcagac gggctgtatt acgcagtcag gtacttgagc
      181 tacatggcat cagccacggt tcggccggag caagaagcat tgccacaatg gcaacccgga
      241 gaggctacca gatgggacgc tggcttgctg gcaggctcat gaaagagctg gggctggtca
      301 gctgtcagca gccgactcac cggtataaac gtggtggtca tgaacatgtt gctatcccta
      361 actaccttga acggcagttc gccgtgaccg agccaaatca ggtgtggtgc ggtgatgtga
      421 cctatatctg gacgggtaag cgctgggcgt acctcgccgt tgttctcgac ctgttcgcaa
      481 gaaaaccagt gggctgggcc atgtcgttct cgccggacag caggctcacc atgaaagcgc
      541 tggaaatggc atgggaaacc cgtggtaaac ccggcggggt gatgttccac agcgatcagg
      601 gtagtcatta tacgagcagg cagttccggc agttattgtg gcgataccag atcacgcaga
      661 gtatgagccg gcgcggaaac tgctgggata acagcccaat ggaacgcttc ttcaggagtc
      721 tgaagaacga atggatgccg gtggtgggtt acgtaagctt cagcgaggca gctcacgcca
      781 taacggacta tatcgttgga tattacagcg cactaagacc gcacgaatat aatggtgggt
      841 tacccccaaa cgaatcggaa aatcgatact ggaaaaactc taactcggtg gccagttttt
      901 gttgaccact tcagatgttt cctgagcaag ccagatcttc atcctctcct gaacacctcc
      961 ctcctatgcc actccacgaa ttcgtcctgc gggtagtatg cttttacctg cggcagagaa
     1021 atgctcttcc cctgaaaatc ccaaaacaac ctaccgacga tcccgctacc gttgaccgct
     1081 tctgaaacct gtactcgcat actctcatct aa
//
LOCUS       DAPOAV010000284         1065 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.296, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000284 DAPOAV010000000
VERSION     DAPOAV010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1065
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.296"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            1..1065
                     /locus_tag="RN951_004708"
                     /pseudo
     CDS             1..1065
                     /locus_tag="RN951_004708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001292293.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
BASE COUNT          353 a          189 c          248 g          275 t
ORIGIN      
        1 atttctatta ttcccgatta cagataagcc tggaaagtag agcataaatt gtcaggcatc
       61 ctactattga ctatttttgc cgttatttct ggtgcagaaa gttgggaaga tatagaggat
      121 ttcggggaaa cacatctcga tttcttgaag caatatggtg attttgaaaa tggtattcct
      181 gttcacgata ctattgccag agttgtatcc tgtatcagtc ctgcaaaatt tcacgagtgc
      241 tttattaact ggatgcgtga ttgccattca tcaaatgata aagacgtcat tgcaattgat
      301 ggaaaaacgc tccggcactc ttatgacaag agtcgccgca ggggagcgat tcatgtcatt
      361 agtgcgttct caacaatgca cagtctggtc atcgggcaga tcaagacgga taagaaatcc
      421 aatgagatca cagctatccc tgaacttctt aacatgctgg atattaaagg aaaaatcatc
      481 acaactgatg cgatgggttg ccagaaagat attgcagaga agatacaaaa acagggaggt
      541 gattatttat tcgctgtaaa aggaaaccag gggcggctta ataaagcctt tgaggaaaaa
      601 tttccgctga aagaattaaa taatccagag catgacagtt acgcaatgag tgaaaagagt
      661 cacggcagag aagaaatccg tcttcatatt gtttgcgatg tccctgatga acttattgat
      721 ttcacgtttg aatggaaagg actgaagaaa ttatgcgtgg cagtctcctt tcggtcaata
      781 atagcagaac aaaagaaaga gccagaaatg acggtcagat attatatcag ttctgctgat
      841 ttaaccgcag aaaagttcgc cacagcaatc cgaaaccact ggcacgtgga gaataagctg
      901 cactggcgtc tggacgtggt aatgaatgaa gacgactgca aaataagaag aggaaacgcc
      961 gcagaattat tttcagggat acggcacatc gctattaata ttttaacgaa tgataaggta
     1021 ttcaaggcag ggttaagacg taagatgcga aaagcagcca tggat
//
LOCUS       DAPOAV010000285         1060 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.297, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000285 DAPOAV010000000
VERSION     DAPOAV010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1060
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.297"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            237..839
                     /locus_tag="RN951_004709"
     CDS             237..839
                     /locus_tag="RN951_004709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDX2529555.1"
                     /translation="MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNK
                     TLARLAQQHPVVVLFRHAERCDRSTNQCLSDKTGITVKGTQDARELGNAFSADIPDFD
                     LYSSNTVRTIQSATWFSAGKKLTVDKRLLQCGNEIYSAIKDLQSKAPDKNIVIFTHNH
                     CLTYIAKNKRDATFKPDYLDGLVMHVEKGKVYLDGEFVNH"
     gene            complement(878..>1060)
                     /gene="nudI"
                     /locus_tag="RN951_004710"
     CDS             complement(878..>1060)
                     /gene="nudI"
                     /locus_tag="RN951_004710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphatase NudI"
                     /protein_id="HDX2529556.1"
                     /translation="HHRRKEEIYMIYLIFDCVSANREVKINEEFQDYAWVKPEDLVHY
                     DLNVTTRKTLRLKGLL"
BASE COUNT          300 a          208 c          217 g          335 t
ORIGIN      
        1 tttggagcga aattttaagg atagaatatt aacttaacct taagaaacta atattagacg
       61 taaatattga aatttttata ttttttctta tttaggcttt gcatttggca aaattttgag
      121 gcattttgcc gacatcgtag gatttttaat attacaccaa ctgctaatta tcgccagaaa
      181 tgtcgctcaa ttttacggta attgtctggt tgcgcttgtc tataggtgga gtttacgtgt
      241 tagctttttg ccgctcatca ttgaagtcaa aaaaatattt catcatttta ctggcgctcg
      301 ctgcaattgc cggactgggt actcatgccg cctggagtag caatggtttg ccacgtatcg
      361 acaataaaac attggccaga ctggcacagc agcacccggt tgtcgttttg tttcgccatg
      421 ctgaacgttg cgatcgttca accaatcaat gcttgtcaga taaaacaggt attacggtta
      481 aaggtaccca ggatgcccgt gaactgggca acgcttttag cgctgacatc cctgatttcg
      541 atctttattc cagtaatacc gtccggacca ttcagtcggc gacctggttt tccgcgggta
      601 aaaagctgac ggtagataaa cgacttcttc agtgcggtaa tgagatttat agtgcaatta
      661 aggacttaca aagcaaagcg cctgataaaa atatcgttat tttcacccat aatcattgcc
      721 tgacatatat tgctaaaaat aagcgtgatg cgacatttaa acctgattat ctggatggtt
      781 tagtcatgca tgtggaaaaa ggcaaagttt atctggatgg ggaattcgtt aaccactaaa
      841 ttttcaatct gacagccagt gatggctgtc atcattgtta aagaagacct ttcaaacgta
      901 acgtttttcg ggtggtaaca tttaaatcat aatgcaccag atcttcaggt tttacccacg
      961 cgtagtcctg aaactcttcg tttattttca cttctcggtt ggcagaaacg cagtcaaaaa
     1021 tcaggtaaat catataaatc tcttccttgc gacggtgatg
//
LOCUS       DAPOAV010000286         1047 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.298, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000286 DAPOAV010000000
VERSION     DAPOAV010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1047
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.298"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..>1047
                     /locus_tag="RN951_004711"
     CDS             <1..>1047
                     /locus_tag="RN951_004711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS66-like element ISEc22 family transposase"
                     /protein_id="HDX2529557.1"
                     /translation="EKLNEREREIDHLQAQLDKLRRMNFGSRSEKVSRRIAQMEADLK
                     ALQKESDTLTGRVDDPAVQRPLRQTRTRKPFPESLPRDEKRLLPAASCCPECGGSLSY
                     LGEDAAEQLELMRSAFRVIRTVREKHACTQCDAIVQAPAPSRPIERGIAGPGLLARVL
                     ISKYAEHTPLYRQSEMYGRQGVELSRSLLSGWVDACCRLLSPLEEALQDYVLTDGKLH
                     ADDTPVPVLLPGNKKTKTGRLWTYVRDDRNAGSTLAPAVWFAYSPDRKGIHPQTHLAG
                     FSGVLQADAYAGFNELYRDGRITEAACWAHARRKIHDVHVRTPSALTEEALKRIGELY
                     AIEAEIRGMTAEQRL"
BASE COUNT          224 a          310 c          333 g          180 t
ORIGIN      
        1 ggaaaagctg aacgagcgtg aacgcgaaat agaccatctg caggcacagc tggataagct
       61 gcgccggatg aacttcggca gccgctcgga aaaagtctcc cgtcgtatcg cacagatgga
      121 agctgacctg aaggcacttc agaaagaaag tgataccctt accggtcggg ttgacgaccc
      181 ggccgtgcag cgcccgctgc gtcaaacccg cacccgcaaa ccgttccccg aatcactccc
      241 ccgcgatgaa aaacggctgc tgccggcagc gtcatgctgc ccggaatgtg gaggctcgct
      301 gagctatctg ggtgaggatg ccgccgaaca gctggagctg atgcgcagcg ccttccgggt
      361 tatccggact gtacgtgaaa agcatgcctg tactcagtgc gatgccatcg tgcaggcccc
      421 cgcgccttca cggcccatcg agcggggtat cgcaggaccg gggctgctgg cccgcgtgct
      481 gatctcaaag tatgcagagc acaccccgct gtaccgccag tctgaaatgt acggccgcca
      541 gggcgtggag ctgagtcgtt cactgctgtc gggctgggtg gatgcatgct gccggctact
      601 gtcaccgctg gaagaagcgc ttcaggacta tgtgctgact gacggtaagc tccatgctga
      661 tgacacgcct gtcccggtgc tgttgccagg caataagaaa acgaagaccg ggcggttatg
      721 gacctacgtt cgtgacgacc gtaacgccgg gtcaacgctg gcgccggcgg tgtggttcgc
      781 ttacagcccg gacagaaaag gcatccatcc gcagacccat cttgcggggt tcagtggtgt
      841 actgcaggcg gatgcatacg ccgggttcaa cgagctgtac cgggatggcc ggataacgga
      901 agccgcctgt tgggctcacg cccgccgtaa aatccacgat gtgcacgttc gcaccccgtc
      961 agccctgacg gaggaagcgc tgaaacggat cggcgaactg tacgccatcg aggcagagat
     1021 aaggggaatg acggcggagc agcgcct
//
LOCUS       DAPOAV010000287         1009 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.300, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000287 DAPOAV010000000
VERSION     DAPOAV010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1009
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.300"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..>1009
                     /locus_tag="RN951_004712"
     CDS             <1..>1009
                     /locus_tag="RN951_004712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDX2529558.1"
                     /translation="DHDFICSNMASDYNNVSDLTDEFKTVSSFRQDIKKPVFHAFLSL
                     PIDEKLTDEKWQEIAKDYLKEMNIDIEKHQYICVRHKDTDQDHIHIVANRVGLDGSVW
                     HGQHSAFNTIAACDRLEVKHSLTITQSLKGQKSDVSAPTKAEIEQALRTGEKPARLVL
                     QNALQAALVGKPDLSTFLERLQAVGIEPAFNVASNGNVAGVSFGIKNNEKNIFFKGSS
                     LGKKFSWNTIKNKVKYDKNRDDELIRRFAARKTYDENSIRRSFVEPNINDDRTIIRND
                     DDIIGVSQHSFKPDTTDTNKSEQLIRGNNNRFKLSEKYNRPTNPKVRRTTQKAAQVLN
                     RV"
BASE COUNT          392 a          176 c          194 g          247 t
ORIGIN      
        1 atgatcatga tttcatttgt agcaatatgg caagtgatta taataatgtt agtgatttaa
       61 ctgatgagtt taaaactgta agcagtttta ggcaagatat aaaaaaacca gtgtttcatg
      121 cgtttttatc tcttccaata gatgaaaaat taacagatga aaaatggcag gagatagcaa
      181 aagattattt gaaagaaatg aatatcgata tagaaaaaca tcaatatatt tgtgtgcgcc
      241 ataaagatac agatcaagac catattcata ttgtagcaaa tagggttggc ttagatggtt
      301 ctgtatggca cggtcagcac tcagcattta atacaatagc agcttgtgat cgtttagaag
      361 taaagcacag cttaaccatt acacaaagtc tcaaaggcca aaaatcagac gtatcagcac
      421 caaccaaagc agagatcgag caagccttga ggacaggtga gaaaccagcc cgtttagtgc
      481 tacagaacgc actacaagcg gctttagtcg gtaagcctga tttgtctacg ttcttggaac
      541 gtctgcaggc tgtaggcatc gagccggcat ttaacgttgc ttctaatggc aacgtcgccg
      601 gagtatcatt tggtatcaaa aataatgaaa aaaatatttt cttcaaggga tcatctcttg
      661 gtaaaaaatt cagttggaac actataaaaa acaaggtgaa atatgacaaa aatagagatg
      721 atgaactcat tagaagattc gcagcaagaa aaacatatga cgaaaatagt attagacgat
      781 catttgttga accaaatatc aatgacgata gaaccattat cagaaacgat gatgatatta
      841 tcggagtcag tcagcacagc tttaaaccag acacaacaga cactaacaag agtgaacaac
      901 tcattagagg caacaacaac cgctttaaac tcagcgaaaa atacaataga ccaacaaacc
      961 caaaagttag aagaacaaca caaaaagctg cacaagtact caacagagt
//
LOCUS       DAPOAV010000288          961 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.306, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000288 DAPOAV010000000
VERSION     DAPOAV010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..961
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.306"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(33..>961)
                     /locus_tag="RN951_004713"
     CDS             complement(33..>961)
                     /locus_tag="RN951_004713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020326821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDX2529559.1"
                     /translation="MSRVWGMGTSASSDGQFFPTARHGEAMNMVNAKYGSVPGLKAYT
                     HVSDQFAPFACQSIPATVSEAPYILDGLLMNEVGRHVREQYADTAGFTDHLFGASSLL
                     GYNLVLRIRDLPSKRLYVFNPDTTPRELRKLVGGKAREDLIVANWPDIFRCAATMTAG
                     KIRPSQLLRKLASYPRQNNLAVALREVGRIERTLFIIEWILDTDMQRRAQIGLNKGEA
                     HHALKNALRIGRQGEIRDRTTEGQHYRIAGLNLLTAVIIYWNTVHLGHAVTERRNEGL
                     DVPPEFLPHISPLGWAHILLTGEYLWPKEPKA"
BASE COUNT          218 a          266 c          263 g          214 t
ORIGIN      
        1 gggtcggttc cggctgaggg cgaaatgaca ccctaagctt tcggttcctt gggccaaaga
       61 tattcgccag tcagtagaat gtgcgcccag cccaatgggg atatgtgggg aagaaattca
      121 gggggaacat ccaacccttc gttccgccgc tccgtgacgg catgaccaag atggacggta
      181 ttccagtaaa tgatcaccgc agtcaataaa ttgagcccag cgattcggta gtgctgcccc
      241 tctgtcgtgc gatcgcgaat ttccccctgc ctcccgatac ggagcgcatt tttgagcgca
      301 tggtgggcct ctcccttgtt aagaccgatc tgagcacgcc gctgcatgtc cgtatccagg
      361 atccactcaa taatgaaaag ggtccgttca atacgaccaa cttcacgaag cgcaactgca
      421 aggttgtttt gtcgtgggta agaagcgagc ttgcgcagga gttggctggg cctgattttg
      481 ccagcggtca tcgtcgcggc acaacggaaa atatcaggcc agttcgcaac gataagatcc
      541 tcccgggctt ttccacctac caacttgcgt aactccctgg gggtcgtatc gggattaaat
      601 acgtacaacc gcttcgatgg cagatccctg attcgcagaa cgagattgta gccgagcagg
      661 ctactggctc cgaacaaatg gtcggtgaat cctgctgtat cggcatactg ttcgcgaaca
      721 tggcgaccga cctcgttcat cagtagtcca tcgagaatat acggtgcctc gctcacggtc
      781 gccgggatcg actgacaagc gaatggcgcg aactggtcgc ttacgtgagt atacgctttg
      841 aggccgggaa cagaaccata tttggcattg accatgttca tggcttcgcc atgccgcgct
      901 gtcgggaaaa actgaccatc gctcgatgct gacgtgccca tcccccagac gcgtgacatc
      961 g
//
LOCUS       DAPOAV010000289          956 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.307, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000289 DAPOAV010000000
VERSION     DAPOAV010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..956
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.307"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            114..746
                     /locus_tag="RN951_004714"
     CDS             114..746
                     /locus_tag="RN951_004714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417323.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDX2529560.1"
                     /translation="MGLCSRYKSLTCNSCSMHCQIMPEESPRLQYCANSCFCMWPEES
                     SYFNRGVVEGILTKNHNARLSGYIFVDFSVSFLRLFLEKDWIDYLASTDMGIVLVSDR
                     NMQSLANYWRKHNSAISAVIYNDDGLDVANEKIRQLFIGRYLSFTRGNTLTQMEFTIM
                     GYMVSGYNPYQIAEVLDMDIRSIYAYKQRIEKRMGGKINELFIRSHSVQH"
BASE COUNT          319 a          165 c          178 g          294 t
ORIGIN      
        1 caaatacaga ttaatcgcaa tttttcccag caaaattaca aaatcatggt gtattgacat
       61 catcaatcac caatgaaatt atgcaattat atacggatag ggaggttctt aacatggggc
      121 tttgtagtcg ttataaaagt cttacatgca atagttgctc aatgcattgc caaataatgc
      181 cagaagagtc accgcgtttg cagtactgcg caaactcgtg tttttgtatg tggcccgaag
      241 aaagttcata ttttaatcgt ggtgtggtag aaggtatctt aacaaaaaac cacaatgcga
      301 gattaagcgg atatattttt gtcgattttt cagtaagttt tttacgtcta ttccttgaaa
      361 aagactggat tgactatctt gcaagtactg acatggggat tgttttagtc agcgaccgca
      421 atatgcaatc gttagctaat tactggcgaa aacacaactc agcaatatct gctgtcatat
      481 ataatgatga tggtcttgat gttgccaatg aaaagatcag acaactattt attggtcgtt
      541 atttatcatt taccagaggt aacacattaa ctcagatgga attcaccata atggggtata
      601 tggtttctgg ttataatcca tatcagattg ctgaagttct ggatatggat atccgtagca
      661 tctacgcgta caagcaacga atcgaaaaga gaatgggtgg taaaataaac gaattattta
      721 ttcgttcaca ttcggtccaa cattgatact caacgaccag ccagaatcat actctgttta
      781 tacgggcatt tattgaaatg tccgtatttt ataaataggc cgtcccctca agagtaaaca
      841 ccatagtatt taaaaccatc acacgaaaaa ttcagaagca ttacgaaata tgaatttaca
      901 aacaatagtg gcataaatgt taaccatgtt aatttacgta aagttttacg ttgcaa
//
LOCUS       DAPOAV010000290          952 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.308, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000290 DAPOAV010000000
VERSION     DAPOAV010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..952
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.308"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..>952
                     /locus_tag="RN951_004715"
     CDS             <1..>952
                     /locus_tag="RN951_004715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001352286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDX2529561.1"
                     /translation="VLTQERLQVLLDNFEEKIDLVVIDEAQSISDEIRGMILQDCLDK
                     ISTQNPNAKYVFLAPGAEGFDDLADIIGIDAIHIEKTNLSPVVQNKIIVKVDPSKENN
                     LQLSLLDNSDILPIGEIESTRGFANENTRLAAVALELGKNEGSLVYGTGAENAEDVAK
                     QISSGLPLLEDDSELQELSKFIKKHVHEDYSLANLVLRGVGYHYGKMPSLLRETLEKN
                     FTNNKLKFLVCTTTLFQGVNLPAKNVFIDTPTRGNRGEKLDPASLWNFAGRAGRLGYA
                     FSGNVYLIDYDDWVTKPLDSKIDFKITSSLKKVINEDFDTV"
BASE COUNT          348 a          148 c          184 g          272 t
ORIGIN      
        1 gtcttaacac aggaaagact tcaagtattg cttgataatt ttgaagaaaa aatagacttg
       61 gtagttattg acgaagcaca atcaatttct gacgaaatta ggggaatgat attacaggac
      121 tgccttgata aaattagcac acaaaaccct aatgcaaaat atgttttcct cgcgcctggt
      181 gctgaaggtt ttgatgattt agcagatatt attggaatcg atgcaatcca tattgaaaaa
      241 acaaatctat ctcctgtagt tcaaaacaaa attatcgtca aagttgatcc atcaaaagaa
      301 aacaacttac aattatcatt attagacaat tcagacatat taccgatcgg agaaatagaa
      361 tcgacaaggg gtttcgccaa tgaaaataca agattggcgg ctgtcgcatt agaattagga
      421 aaaaatgagg ggtctttagt ttacggaacc ggagctgaaa atgcagaaga tgtagctaag
      481 caaatatctt ctggattacc tcttttagag gatgacagtg aattacaaga actctcaaaa
      541 tttataaaaa aacatgtcca cgaggattac tctcttgcaa acctcgtatt gagaggggtt
      601 ggataccatt atggtaaaat gccaagttta ttaagagaaa cattagaaaa aaatttcacg
      661 aataataaac tgaagttttt agtttgcaca acaacccttt ttcaaggggt taatctgcct
      721 gcaaagaatg tttttattga tacacctaca cgaggaaaca ggggagaaaa attagatcca
      781 gcatcgctat ggaatttcgc agggcgggca ggtagattag gttatgcatt ttcgggaaat
      841 gtttatctta ttgactatga tgattgggta accaagcctt tagattccaa aatagacttc
      901 aaaattactt catctttaaa gaaagtaatt aatgaagatt ttgacacagt aa
//
LOCUS       DAPOAV010000291          951 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.309, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000291 DAPOAV010000000
VERSION     DAPOAV010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..951
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.309"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            1..951
                     /locus_tag="RN951_004716"
                     /pseudo
     CDS             1..951
                     /locus_tag="RN951_004716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439272.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          341 a          180 c          179 g          251 t
ORIGIN      
        1 gataacatct ctaaggatga atgggaaaac ctccatgcat taaaagaaaa gcgtttaaat
       61 ggaatgccta aaacaacacc caaaagtgac caggttatta tgttgcaaaa tcaatacgtt
      121 cgtgaaatgc gaaaatatgg cgtacgaggt ttacgttacg atgcagcaaa acactcaaaa
      181 catgaacaaa tagaaagatc aataactcca ccgcttaaaa attataatga gcggttacac
      241 aatactaatt tatttaaccc aaaatatcaa aaaaaagccg ttatgaatta catggaatac
      301 ctggtaactt gtcagttgga tgaacaacaa atgtcatcgc tgctttatga aagagatgat
      361 ttaagcgcca ttgatttttc attgctcatg aaaacgataa aagccttttc atttggtggc
      421 gatctccaaa cccttgcatc aaaaccgggt tccacaatct caagtatccc atcagaaaga
      481 cggatattga ttaatcatta accacgattt tccaaacaat ggcaatcttt tcaatgactt
      541 tctatttaac catcaacaag atgaacaatt agcaatggca tatatagccg ctctgccgtt
      601 cagcaggcct ttagtttact gggatggcca agtattaaaa tcaacgactg aaattaaaaa
      661 ttatgatggg tccacgcgtg tcggcggtga ggcgtagctt aataaaggtt gctctaccta
      721 tcagcagctc tacaatgaat tccacgcatt atatatagat aaagcaggaa tatggagcgc
      781 atttgagggt gtatctgcaa ctaaaaacgt tctggccttt agtcgtgggg attctgtgaa
      841 cattaatcac tctcctcatg atggactagt tataataaat aaaggaaacg aagaagttga
      901 aggtacctgg cctaacaaat tgcaacctgg aatatacaaa aacatgggga g
//
LOCUS       DAPOAV010000292          940 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.310, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000292 DAPOAV010000000
VERSION     DAPOAV010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..940
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.310"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            51..836
                     /locus_tag="RN951_004717"
     CDS             51..836
                     /locus_tag="RN951_004717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529562.1"
                     /translation="MNSKKLCCICVLFSLLAGCASESSIDEKKKKAQVTQSNINKNTP
                     QQLTDKDLFGNETTLAVSEEDIQAALDGDEFRVPLNSPVILVQSGNRAPETIMQEEMR
                     KYYTVSTFSGIPDRQKPLTCNKNKDKNENEDVASAENMNWMQALRFVAAKGHQKAIIV
                     YQDMLQTGKYDSALKSTVWSDYKNDKLTDAISLRYLVRFTLVDVATGEWATWSPVNYE
                     YKVLPPLPDKNEASTTDMTEQQIMQLKQKTYKAMVKDLVNRYQ"
BASE COUNT          311 a          189 c          203 g          237 t
ORIGIN      
        1 atcaatgcta aatattctaa tcattatgac aggcgaggga gtgtccaatt atgaattcaa
       61 aaaagctttg ttgcatatgt gtgttattct cgctgcttgc aggatgtgcc tctgaatctt
      121 ctattgatga aaagaagaaa aaagctcaag tcacacaaag taatattaat aaaaacactc
      181 cccagcaact gacagacaaa gatttattcg gtaatgaaac cactctggcc gtatccgaag
      241 aggatattca agctgcgctt gatggagatg agttccgcgt tccccttaat tctcctgtaa
      301 tacttgttca atccggcaac cgcgcaccgg aaaccattat gcaggaggag atgcgaaaat
      361 attatactgt ttccacattc tctggtatcc cggacaggca aaagcctctg acttgtaaca
      421 aaaacaaaga taaaaatgag aacgaggatg ttgccagtgc tgagaatatg aactggatgc
      481 aggcactgcg ttttgtggct gcaaaaggac atcagaaagc gattattgtt taccaggata
      541 tgttgcagac aggaaaatat gactctgcgc tgaaatcaac agtatggtcc gactataaaa
      601 atgacaaact cactgacgct atctccctgc gctacctggt acgtttcacg ctggtggatg
      661 tggcaacagg tgagtgggct acctggtcgc cggtgaatta tgaatataaa gtgcttccac
      721 cattgcccga caagaatgaa gccagtacga ctgatatgac agagcagcaa atcatgcaac
      781 ttaagcaaaa gacctataaa gcgatggtaa aagatttggt taaccgctat caataataaa
      841 ttatatctgc cgccaggaat ttctggcggc aataatacaa aattctttgc ataagaaatt
      901 tttcttgaca aagacagtgc aagaaaggac atggaatccg
//
LOCUS       DAPOAV010000293          911 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.311, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000293 DAPOAV010000000
VERSION     DAPOAV010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..911
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.311"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(146..886)
                     /locus_tag="RN951_004718"
     CDS             complement(146..886)
                     /locus_tag="RN951_004718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HDX2529563.1"
                     /translation="MFFNTKHTTALCFVTCMAFSSSSIADIVISGTRVIYKSDQKSVN
                     VRLENKGNNPLLVQSWLDTGDDNAEPGSITVPFTATPPVSRIDAKRGQTIKLMYTAST
                     SLPKDRESVFWFNVLEVPPKPDAEKVANQSLLQLAFRTRIKLFYRPDGLKGNPSEAPL
                     ALKWFWSGSEGKASLRVTNPTPYYVSFSSGDLEASGKRYPIDVKMIAPFSDEVMKVNG
                     LNGKANSAKVHFYAINDFGGAIEGNARL"
BASE COUNT          249 a          203 c          195 g          264 t
ORIGIN      
        1 atggtcatat tcaacgagtt cagcactgaa agcagtattg caatacagca gcgcgcaaaa
       61 cgtggcgata cgggtcagat gatgataatt tttagtatat tctatagtca cgctatgctt
      121 cctgcggaat tatatccttg cctgattaca gcctggcatt accttcaatt gcgccaccaa
      181 agtcattaat ggcgtaaaaa tgcacttttg cagaattcgc tttgccatta aggccattga
      241 ctttcatgac ctcatcacta aatggtgcaa tcattttcac atcaatcgga tagcgtttac
      301 cgctagcttc taaatcacca ctgctaaaag agacgtagta aggggttgga ttggtcactc
      361 gtaatgacgc cttaccttct gaacctgacc agaaccactt cagggctaac ggggcttcag
      421 agggatttcc cttcaatcca tccgggcgat agaaaagttt tatacgtgtg cgaaatgcca
      481 gttgcagcag gctttgattc gcgacctttt ctgcatctgg ttttggtgga acttccagta
      541 cgttaaacca gaacacgctc tctctgtctt taggcagtga ggtgctggct gtgtacatta
      601 atttgattgt ttgcccacgt ttggcatcaa tacgcgatac tggcggcgta gcagtaaaag
      661 ggactgtaat actgccaggc tcagcgttgt catcgccagt atctaaccaa ctctggacaa
      721 gcaacgggtt attcccttta ttttccagac gtacgttgac acttttttga tcgcttttat
      781 atattacgcg agtacccgaa atgacaatgt ccgcaataga cgatgaacta aaagccatac
      841 aggttacgaa gcataaagct gttgtatgtt tggtgttaaa aaacataaac catccctgat
      901 agagttaatt a
//
LOCUS       DAPOAV010000294          870 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.313, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000294 DAPOAV010000000
VERSION     DAPOAV010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..870
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.313"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            96..344
                     /locus_tag="RN951_004719"
     CDS             96..344
                     /locus_tag="RN951_004719"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529564.1"
                     /translation="MGDGSTLRAITLEDVFYILLLKEILSEKANLLIINPTIAMTNKL
                     ILPAIIPELIPIKNDNIKVLNTIKNTHQPGGAPYNTVA"
     gene            complement(430..717)
                     /locus_tag="RN951_004720"
     CDS             complement(430..717)
                     /locus_tag="RN951_004720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529565.1"
                     /translation="MRKFMLVAGLAVLLAGCGDDGIYGNYVNQQFGVRLDIQKDVIKF
                     RDGVFTVKSWDESKKPIYIAKTQNKNLGSWTFKIEKVKDGVVYQGAVFKKD"
BASE COUNT          270 a          192 c          149 g          259 t
ORIGIN      
        1 atttgggggg ggaatcgtca agggctaaat cgtggggtcc cgcttgcggg ttccgattta
       61 gtgcttgatg atatagagga ggaaataaaa tttatatggg tgatggttcg acacttcgag
      121 ccatcacctt ggaagacgta ttttacattc tccttctgaa agaaatcctg tcagaaaaag
      181 ccaacttgct aataataaac ccaacaatcg caatgacaaa taaactaata ttaccagcca
      241 ttattcctga actcataccg atcaaaaatg ataatattaa ggtgctgaat actattaaaa
      301 atacacacca acccggcgga gcaccgtata ataccgttgc ttgacatcca gtgcatacgt
      361 gaaccccttt ctgactttct tttagacagt atgggcattg aatggtatta ttttccattt
      421 cctactcctc taatctttct taaaaaccgc accttggtaa acaactccat ctttgacttt
      481 ttcgatttta aaagtccaag atccgagatt tttgttttgc gttttggcga tatagatggg
      541 tttcttgctt tcatcccagc ttttaactgt aaaaacacca tcgcgaaact tgatcacatc
      601 tttctgaata tcaagcctga cgccgaactg ttgattaaca tagttgccat agatgccatc
      661 atcgccacac cctgctagca ggacggcaag acctgccact aacataaatt tccgcatacc
      721 ttttccttca ccaatagcac agatctacga ttgacctgta aacgccttag gattcaatta
      781 ttttcatgtc tagtcatatc gtttgtaccg atcgaaaaaa taagcaatga tagataaaag
      841 ctatcaaaaa caaataactg atcgtttaaa
//
LOCUS       DAPOAV010000295          852 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.314, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000295 DAPOAV010000000
VERSION     DAPOAV010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..852
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.314"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..702)
                     /locus_tag="RN951_004721"
     CDS             complement(<1..702)
                     /locus_tag="RN951_004721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529566.1"
                     /translation="MNRIYRVIWNCTLQVFQACSELTRRAGKTSTVNLRKSSGLTTKF
                     SRLTLGVLLALSGSASGASLEVDNDQITNIDTDVAYDAYLVGWYGTGVLNILAGGNAS
                     LTTITTSVIGANEDSEGTVNVLGGTWRLYDSGNNARPLNVGQSGTGTLNIKQKGHVDG
                     GYLRLGSSTGGVGTVNVEGEDSVLTTELFEIGSYGTGSLNITDKGYVTSSIVAILGYQ
                     AGSNGQVVVEKGGEWL"
BASE COUNT          245 a          222 c          161 g          224 t
ORIGIN      
        1 tagccactcg ccaccctttt caacgacaac ctggccatta ctgcccgcct gatagcctaa
       61 aatggcgacg attgaactcg tgacgtaacc cttatccgta atatttaatg aacctgtgcc
      121 atagctacct atttcgaata attcggtcgt cagaacagag tcctctccct caacattgac
      181 cgtcccgacg cctcctgtcg aagaacctaa tcttaaatag cctccatcga cgtgaccctt
      241 ctgtttaata ttcagcgtcc ccgttccgga ttgacccaca tttaaaggcc ttgcattatt
      301 tccgctatca tacaatcgcc aggtgccacc caaaacatta acggtgccct ctgagtcctc
      361 attagcgcca atgacgctgg tagtaatagt ggttaaggag gcattaccgc cagccaaaat
      421 attaagcact ccagtgccat accagccaac caggtaggca tcataagcaa catcagtatc
      481 aatattggta atctgatcat tatcaacttc cagacttgca ccagacgctg aaccgcttag
      541 tgccagcaaa acacccagcg tcaatctact gaatttcgtt gtcagtccag aggatttacg
      601 caaattaacc gtcgatgttt tacctgccct gcgagttaat tccgagcagg cctgaaatac
      661 ctgtagagtg caattccata tcacgcgata gattctattc atataaacgc tccatataca
      721 aacaatacag ccacgaaaga gatgagtcgt cagacattaa aaatgaaact tattaaattg
      781 tcagaggtct gtattgagtg ttagttggag gtgggaaggt gtcaatttgg ctaatttgct
      841 aatgctttcg aa
//
LOCUS       DAPOAV010000296          852 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.315, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000296 DAPOAV010000000
VERSION     DAPOAV010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..852
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.315"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            237..839
                     /gene="fimB"
                     /locus_tag="RN951_004722"
     CDS             237..839
                     /gene="fimB"
                     /locus_tag="RN951_004722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria switch DNA invertase FimB"
                     /protein_id="HDX2529567.1"
                     /translation="MKNKADNKKRNFLTHSEIESLLKAANTGPHAARNYCLTLLCFIH
                     GFRASEICRLRISDIDLKAKCIYIHRLKKGFSTTHPLLNKEVQALKNWLSIRTSYPHA
                     ESEWVFLSRKGNPLSRQQFYHIISTSGGNAGLSLEIHPHMLRHSCGFALANMGIDTRL
                     IQDYLGHRNIRHTVWYTASNAGRFYGIWDRARGRQRHAVL"
BASE COUNT          248 a          162 c          190 g          252 t
ORIGIN      
        1 tcgtatccga ttgataaata tataaaggta catagcatgc aagagcatag cgtttgtatg
       61 gcaacgttat tataattaac tgttgctact ccatttaagt tcactcagaa gaactggtcc
      121 acttacgtta gttattaagc aaacgttcgc ttttataaac ataatcagga taaaaatgtt
      181 ggattattgc taacccagca cagctagtgc gcgtctgtaa ttataaggga aaaacgatga
      241 agaataaggc tgataacaaa aaaaggaact tcctgaccca tagtgaaatc gaatcactcc
      301 ttaaagcagc aaataccggg cctcatgcag cacgtaatta ttgtctgact ttgctttgtt
      361 ttattcatgg tttccgggcg agtgaaattt gtcgattgag gatttcggat attgatctta
      421 aggcaaagtg tatatatatc catcgattaa aaaaaggctt ttcaacaacg cacccgctat
      481 tgaacaaaga agttcaggct ttaaaaaact ggttgagtat ccgtacttcg tacccgcatg
      541 ctgagagcga gtgggtattt ttatcgcgta aggggaatcc gctttctcgg caacagtttt
      601 accatattat ctcgacttcc ggtggtaatg ccgggttgtc actggagatt catccgcaca
      661 tgttacgcca ttcgtgtggt tttgctttgg cgaatatggg aatagatacg cgacttatcc
      721 aggattatct tgggcatcgc aatattcgtc atactgtctg gtataccgcc agcaatgcag
      781 ggcgttttta cggcatctgg gatagagcca gaggacgaca gcgtcacgct gttttataga
      841 gatagttgag at
//
LOCUS       DAPOAV010000297          851 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.316, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000297 DAPOAV010000000
VERSION     DAPOAV010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..851
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.316"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..614
                     /locus_tag="RN951_004723"
     CDS             <1..614
                     /locus_tag="RN951_004723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDX2529568.1"
                     /translation="LLRLPGTPPQPTPERKSVSLKRDCLPYLLCAMLLAAAMSMMQLG
                     LSPALTRQFDTDTTTISQQVAWLLGLSAIAALIAQFVVLRPQRLTPVALLLSAGVLMS
                     SGLAIMLTEQLWLFYLGCAVLSFGAALATPAYQLLLNDKLADGAGAGWLAASHTLGYG
                     LCALLVPLASKTGVSIALIVTALFAAVLFTIVSACIWHYRTIK"
BASE COUNT          175 a          223 c          234 g          219 t
ORIGIN      
        1 tgcttctgcg gttgcccggc acaccaccac agcccacacc ggagcgcaag agcgtcagcc
       61 tgaagcggga ttgcctgcct tatctgcttt gcgcaatgtt actggctgcg gcaatgagca
      121 tgatgcagct tggactttcg ccagccctta ctcgccagtt cgatactgat accaccacta
      181 ttagccaaca ggtggcgtgg ttgttggggc tgtccgcaat agctgcgctt atcgcgcagt
      241 tcgtggtact ccgtccacag cgcctgactc cagtggctct gctcctgagt gccggggtgt
      301 tgatgagtag tggtctggct atcatgctca ctgaacagct atggttgttt tacctgggct
      361 gtgcagtgct gtcatttggg gccgctctgg caacacccgc ttatcaactt ttactgaatg
      421 ataagctggc cgacggcgca ggcgcgggct ggcttgcggc cagtcacaca cttggctatg
      481 ggctgtgcgc attgttggtg ccactggcgt cgaaaacagg tgtctcaatc gcgctgattg
      541 tgacggcatt atttgccgct gtattattta ccatagtgtc tgcatgtatt tggcattacc
      601 gtacaatcaa gtaaggctat gatgttgtac tcacagccgg cataacgtcc tgtgcaattt
      661 cgctgtcgaa accgcctgtg ctgaccgccc agtgcactca cctgaagcac atcgcagcat
      721 gccaccagga tgccagatcg tcttctgaaa tgggtggata cattggcaac gttaaccgca
      781 acaatttttc agagagaatt ttggggggtg agggccagtg atgtaaaaaa tacgccaaga
      841 ggttaattca t
//
LOCUS       DAPOAV010000298          848 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.317, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000298 DAPOAV010000000
VERSION     DAPOAV010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..848
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.317"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..>848
                     /locus_tag="RN951_004724"
     rRNA            <1..>848
                     /locus_tag="RN951_004724"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          231 a          182 c          267 g          168 t
ORIGIN      
        1 gggacacgtg gtatcctgtc tgaatatggg gggaccatcc tccaaggcta aatactcctg
       61 actgaccgat agtgaaccag taccgtgagg gaaaggcgaa aagaaccccg gcgaggggag
      121 tgaaaaagaa cctgaaaccg tgtacgtaca agcagtggga gcacgcttag gcgtgtgact
      181 gcgtaccttt tgtataatgg gtcagcgact tatattctgt agcaaggtta accgaatagg
      241 ggagccgaag ggaaaccgag tcttaactgg gcgttaagtt gcagggtata gacccgaaac
      301 ccggtgatct agccatgggc aggttgaagg ttgggtaaca ctaactggag gaccgaaccg
      361 actaatgttg aaaaattagc ggatgacttg tggctggggg tgaaaggcca atcaaaccgg
      421 gagatagctg gttctccccg aaagctattt aggtagcgcc tcgtgaattc atctccgggg
      481 gtagagcact gtttcggcaa gggggtcatc ccgacttacc aacccgatgc aaactgcgaa
      541 taccggagaa tgttatcacg ggagacacac ggcgggtgct aacgtccgtc gtgaagaggg
      601 aaacaaccca gaccgccagc taaggtccca aagtcatggt taagtgggaa acgatgtggg
      661 aaggcccaga cagccaggat gttggcttag aagcagccat catttaaaga aagcgtaata
      721 gctcactggt cgagtcggcc tgcgcggaag atgtaacggg gctaaaccat gcaccgaagc
      781 tgcggcagcg acactatgtg ttgttgggta ggggagcgtt ctgtaagcct gtgaaggtgt
      841 gctgtgag
//
LOCUS       DAPOAV010000299          835 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.319, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000299 DAPOAV010000000
VERSION     DAPOAV010000299.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..835
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.319"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..766)
                     /locus_tag="RN951_004725"
     CDS             complement(<1..766)
                     /locus_tag="RN951_004725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529569.1"
                     /translation="MSIDFTPGIINTYHGDIYNCTTNTDNVKTPDTSKWPCDNWEEQQ
                     PINSTFSGEGYNPEQFDLAQQQLQQINACHTNTTYTNADYSKVVVQLVSLINNIETIS
                     STPLTQQTQSILNQIHNIRYEKDKDSVCQIIVVVNPEPNNPIITKILVEEGIPEIFSV
                     QTVSSDNKNFAGQRADLPTDIRDIQSLYLKMAKLYIEHSENENRMEALAGCDFIDFNM
                     TGQDMSRLVLTLSNFYFEDLLNINFTDANLFNTIFSH"
BASE COUNT          232 a          125 c          164 g          314 t
ORIGIN      
        1 tgtgtgaaaa aatagtgtta aataaatttg cgtcagtgaa atttatatta agtagatctt
       61 caaaataaaa atttgataag gttaggacta gcctagacat atcttgccct gtcatgttga
      121 aatcaataaa gtcgcatcca gcaagggctt ccatcctatt ttcattttca ctgtgctcaa
      181 tatacagctt cgccattttt aagtacaagc tttgaatgtc tcttatatca gttggtaagt
      241 cagctcgttg cccagcaaaa tttttattat cggaagaaac ggtttggaca ctgaatattt
      301 cgggtattcc ttcttctacg agaattttag ttatgattgg attgttgggt tctggattaa
      361 cgacaacaat gatttgacat acagaatcct tatccttttc gtatctaatg ttatgaatct
      421 gattaagtat tgattgtgtc tgttgcgtaa gtggtgtcga acttatcgtt tcaatgttat
      481 taataagact tacaagttga accacaactt ttgagtagtc tgcatttgta tatgtggtgt
      541 tcgtgtggca tgcattaatt tgttggagtt gttgttgcgc taaatcaaat tgttcagggt
      601 tgtatccttc tccagagaat gtggaattaa tgggttgttg ttcttcccaa ttatcacaag
      661 gccacttcga tgtgtctggc gttttaacat tatcggtatt tgttgtgcag ttataaatat
      721 cgccgtgata tgtatttatt atacctgggg taaagtcaat tgacataaca ttccttattc
      781 atcatctgtt ttatgctaag gtttttaaat tggataatta gaacaggaat ggatt
//
LOCUS       DAPOAV010000300          796 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.321, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000300 DAPOAV010000000
VERSION     DAPOAV010000300.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..796
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.321"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..>796
                     /locus_tag="RN951_004726"
     CDS             <1..>796
                     /locus_tag="RN951_004726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HDX2529570.1"
                     /translation="SDLPCATEDATGSRKTMTWSRYGQLLSFTDCSGYVTRYDHDRFG
                     QMTAVHREEGLSQYRAYDSRGQLIAVKDTQGHETRYEYNIAGDLTAVIAPDGSRNGTQ
                     YDAWGKAVRTTQGGLTRSMEYDAAGRVIRLTSENGSHTTFRYDVLDRLIQETGFDGRT
                     QRYHHDLTGKLIRSEDEGLVTHWHYDEADRLTHRTVKGETAERWQYDERGWLTDISHI
                     SEGHRVAVYYGYDEKGRLTGERQTVHHPQTEALLWQHETRHAYNAQG"
BASE COUNT          196 a          228 c          249 g          123 t
ORIGIN      
        1 agtgacttac cctgcgcaac ggaagatgcc accggcagcc ggaaaaccat gacgtggagc
       61 cgttacggtc agttgctgag cttcaccgac tgttccggtt atgtaacccg ttatgaccat
      121 gaccgcttcg ggcagatgac ggcggtgcac cgcgaggaag ggctgagtca gtaccgcgca
      181 tacgacagcc gtggacagtt aattgccgtg aaagacacgc agggccatga aacgcggtat
      241 gaatacaaca tcgccggtga cctgaccgcc gtcattgccc cggacggcag cagaaacggg
      301 acacagtacg atgcgtgggg aaaggccgtc cgtaccacgc agggcgggct gacgcgcagt
      361 atggaatacg atgctgccgg acgggtcatc cgcctgacca gtgaaaacgg cagccacacc
      421 accttccgtt acgatgtact tgaccggctg atacaggaaa ccggctttga cggccgcaca
      481 cagcgttatc accacgacct gaccggcaaa cttatccgca gcgaggatga gggtctggtc
      541 acccactggc actatgacga agcagaccgc ctcacgcacc gcaccgtgaa gggtgaaacc
      601 gcagagcggt ggcagtatga cgaacgtggc tggctgacag acatcagcca tatcagcgaa
      661 gggcaccggg tggcggtgta ttacggatat gatgagaaag gccggctgac cggtgagcgt
      721 cagacggtgc atcacccgca gacggaagca ctgctctggc agcatgagac cagacatgcg
      781 tacaacgcgc aggggc
//
LOCUS       DAPOAV010000301          794 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.323, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000301 DAPOAV010000000
VERSION     DAPOAV010000301.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..794
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.323"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            97..>794
                     /locus_tag="RN951_004727"
     CDS             97..>794
                     /locus_tag="RN951_004727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDX2529571.1"
                     /translation="MGRKWANIVAKKTAKDGATSKIYAKFGVEIYAAAKQGEPDPELN
                     TSLKFVIERAKQAQVPKHVIDKAIDKAKGGGDETFVQGRYEGFGPNGSMIIAETLTSN
                     VNRTIANVRTIFNKKGGNIGAAGSVSYMFDNTGVIVFKGTDPDHIFEILLEAEVDVRD
                     VTEEEGNIVIYTEPTDLHKGIAALKAAGITEFSTTELEMIAQSEVELSPEDLEIFEGL
                     VDALEDDDDVQKVY"
BASE COUNT          265 a          133 c          172 g          224 t
ORIGIN      
        1 tagacgagat ttttcctgtt atgatataat atgccgaatt aacacatgtt aacgatttac
       61 cagtaatgta aataaatttt cgaggagatc attccagtgg gacgtaaatg ggccaatatt
      121 gttgctaaaa aaacggctaa agacggtgca acgtctaaaa tttatgcaaa attcggtgta
      181 gaaatctatg ctgctgccaa acaaggtgaa cccgatccag aattaaacac atctttaaaa
      241 ttcgttattg aacgtgcaaa gcaggcacaa gttccaaagc acgttattga taaagcaatt
      301 gataaagcca aaggcggcgg agatgaaacg ttcgtacagg gacgttatga aggctttggt
      361 cctaatggct caatgattat tgctgagaca ttgacttcaa atgttaaccg tacgattgct
      421 aacgttcgca caattttcaa taaaaaaggc ggcaatatcg gagcggcagg ttctgtcagc
      481 tatatgtttg acaatacggg tgtgattgta tttaaaggaa cagaccctga ccatattttt
      541 gaaattttgc ttgaagctga agttgatgtt cgtgatgtaa ctgaagaaga aggtaatatt
      601 gttatttata ctgaacctac tgaccttcat aaaggaatcg cggcgctaaa agcagctgga
      661 atcactgagt tctcaacaac agaattagaa atgattgctc aatctgaagt tgagctttcc
      721 ccagaagatt tagaaatctt tgaagggctt gttgatgccc ttgaagatga cgacgatgta
      781 caaaaagttt atca
//
LOCUS       DAPOAV010000302          784 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.324, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000302 DAPOAV010000000
VERSION     DAPOAV010000302.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..784
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.324"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     repeat_region   72..649
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=72..100
                     /rpt_unit_seq="gtgttccccgcgccagcggggataaaccg"
BASE COUNT          181 a          212 c          202 g          189 t
ORIGIN      
        1 tgtgatacta taaagttggt agattgtgac tggcttaaaa aatcattaat taataatagg
       61 ttatgtttag agtgttcccc gcgccagcgg ggataaaccg ttgattacct cgctgttgct
      121 gcgctactgg tggtgttccc cgcgccagcg gggataaacc ggcgtttcca tgccgttgat
      181 aaacatcccg cccgtgttcc ccgcgccagc ggggataaac cgggttgcca tcgctgacgc
      241 aacgtcatta aggcgtgttc cccgcgccag cggggataaa ccgggaataa ttaccgcgct
      301 gattaaatta attaagtgtt ccccgcgcca gcggggataa accggcggca gcgcccgccg
      361 ggtacgacgg cagcacgtgt tccccgcgcc agcggggata aaccgcgctt ttgctcagta
      421 gtgagtgtga tttcatcgtg ttccccgcgc cagcggggat aaaccgcagg tacagccgtt
      481 tcggtgtttt gtttttgtgt gttccccgcg ccagcgggga taaaccggcg tcgctggaag
      541 aacaaaaccg cctgatcgag tgttccccgc gccagcgggg ataaaccggc accacgcgta
      601 ccccgatgtt tgttttgcca gtgttccccg cgccagcggg gataaaccac catataaccc
      661 gttatctctt tctcaagttt ttatattagc agtacttgta ataagcaaca tatccacgta
      721 acccctcatg ttcaaaatag ttctccatgc cagagaagtt cacaattatc gatacaaaaa
      781 atta
//
LOCUS       DAPOAV010000303          770 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.325, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000303 DAPOAV010000000
VERSION     DAPOAV010000303.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..770
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.325"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..727
                     /gene="istB"
                     /locus_tag="RN951_004728"
     CDS             <1..727
                     /gene="istB"
                     /locus_tag="RN951_004728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS21-like element IS100kyp family helper ATPase
                     IstB"
                     /protein_id="HDX2529572.1"
                     /translation="ESLISAAPALSQQAVDQEWSYMDFLEHLLHEEKLARHQRKQAMY
                     TRMAAFPAVKTFEEYDFTFATGAPQKQLQSLRSLSFIERNENIVLLGPSGVGKTHLAI
                     AMGYEAVRAGIKVRFTTAADLLLQLSTAQRQGRYKTTLQRGVMAPRLLIIDEIGYLPF
                     SQEEAKLFFQVIAKRYEKSAMILTSNLPFGQWDQTFAGDAALTSAMLDRILHHSHVVQ
                     IKGESYRLRQKRKAGVIAEANPE"
BASE COUNT          222 a          187 c          197 g          164 t
ORIGIN      
        1 ggaaagcctt ataagcgcag cgcctgcgct gtcacaacag gcagtagacc aggaatggag
       61 ttatatggac ttcctggagc atctgcttca tgaagaaaaa ctggcacgtc atcaacgtaa
      121 acaggcgatg tatacccgaa tggcagcctt cccggcggtg aaaacgttcg aagagtatga
      181 cttcacattc gccaccggag caccgcagaa gcaactccag tcgttacgct cactcagctt
      241 catagaacgt aatgaaaata tcgtattact ggggccatca ggtgtgggga aaacccatct
      301 ggcaatagcg atgggctatg aagcagtccg tgcaggtatc aaagttcgct tcacaacagc
      361 agcagatctg ttacttcagt tatctacggc acaacgtcag ggccgttata aaacgacgct
      421 tcagcgtgga gtaatggccc cccgcctgct catcattgat gaaataggct atctgccgtt
      481 cagtcaggaa gaagcaaagc tgttcttcca ggtcatcgct aaacgttacg aaaagagcgc
      541 aatgatcctg acatccaatc tgccgttcgg gcagtgggat caaacgttcg ccggtgatgc
      601 agcactgacc tcagcgatgc tggaccgtat cttacaccac tcacatgtcg ttcaaatcaa
      661 aggagaaagc tatcgactca gacagaaacg aaaggccggg gttatagcag aagctaatcc
      721 tgagtaaaac ggtggatcaa tattgggccg ttggtggaga tataagtgga
//
LOCUS       DAPOAV010000304          757 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.326, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000304 DAPOAV010000000
VERSION     DAPOAV010000304.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..757
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.326"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..111)
                     /locus_tag="RN951_004729"
     CDS             complement(<1..111)
                     /locus_tag="RN951_004729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraL"
                     /protein_id="HDX2529573.1"
                     /translation="MSGDENKLKKYRFPETLTNQSRWFGLPLDELIPAAIC"
     gene            complement(126..485)
                     /gene="traA"
                     /locus_tag="RN951_004730"
     CDS             complement(126..485)
                     /gene="traA"
                     /locus_tag="RN951_004730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system pilin TraA"
                     /protein_id="HDX2529574.1"
                     /translation="MNTVLSVQGASAPVEKKSFFSKFTRLNMLRLVRAVIPVAVLMML
                     FPELAMAAGKGDLMAKGNDTVKATFGKDSSIVKWVVLAEVLVGAVMYMMTKNVKFLVG
                     FAIISVFIAVGMSVVGL"
     gene            complement(518..745)
                     /gene="traY"
                     /locus_tag="RN951_004731"
     CDS             complement(518..745)
                     /gene="traY"
                     /locus_tag="RN951_004731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016241852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer relaxosome protein TraY"
                     /protein_id="HDX2529575.1"
                     /translation="MSRNIIRPAPGNKVLLVLDDATNHKLLGARERSGRTKTNEVLVR
                     LRDHLNRFPDFYNLDAIKEGAEETDSIIKDL"
BASE COUNT          216 a          197 c          145 g          199 t
ORIGIN      
        1 acagattgct gcggggatca gttcatccag tggcaggcca aaccagcggc tctggttggt
       61 cagtgtttcc gggaaacgat atttcttaag tttattctcg tctcccgaca tcgttttatt
      121 tcctgtcaga ggccaacgac gctcataccc acagcaataa atacagagat gatggcaaag
      181 ccgaccagga acttgacgtt tttggtcatc atgtacatga ccgcaccgac cagcacctca
      241 gccagaacaa cccatttaac gatactggag tccttaccga aggtcgcctt aaccgtatcg
      301 ttacctttag ccatcaggtc gcctttacca gcagccatag ctaactcagg gaacaacatc
      361 atcagaacag caaccgggat cactgcacga accaggcgaa gcatattcag acgagtgaat
      421 ttagaaaaaa acgatttctt ttcaacgggc gcagaagcac cctgaacact taaaacagta
      481 ttcataagtt acctctattg tggatagatt aataaaccta aagatcttta attatcgaat
      541 cagtttcctc tgctccctcc tttattgcat ccagattata aaagtcagga aaacggttca
      601 gatgatcacg taacctgact agcacctcat tagtttttgt tctcccacta cgttcccggg
      661 cacctaagag cttgtgatta gtagcatcgt ccaataccag taaaacttta ttgcccggag
      721 caggccttat tatatttctg ctcaagtctc ctcctca
//
LOCUS       DAPOAV010000305          752 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.327, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000305 DAPOAV010000000
VERSION     DAPOAV010000305.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..752
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.327"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..144)
                     /gene="hokD"
                     /locus_tag="RN951_004732"
     CDS             complement(<1..144)
                     /gene="hokD"
                     /locus_tag="RN951_004732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokD"
                     /protein_id="HDX2529576.1"
                     /translation="MKQQKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVF
                     TAYE"
BASE COUNT          208 a          180 c          162 g          202 t
ORIGIN      
        1 ttcgtaagct gtgaagacag cgacctccgt ctggccggtt cggattcgta cctcgcagag
       61 gtctttcctc gttaccagtg ccgtcactat gacggttaaa cagatgacga tcagggcgat
      121 tagcatcgcc ttttgctgct tcatagcctg cttctccttg cctttcggca cgtaagaggc
      181 taacctacgt gtgtagagca tagatatggc ctcagattaa tgttaagcgt cttgccggac
      241 gcgtaatgtt aactggggct tttctctatc tgcctttggt gttgatgccc gaggcagata
      301 gcctcaagca cccgcagcaa ttctacttaa ctaccgttac ctcgccaata tgaaatcaat
      361 cagaaaggtg atccataaga acaacagcaa gacaataaat tgccattaca gcagcaatag
      421 ccagcgcaca tttgagaacc agcaccacaa cctcctgtat tggacgtaca ccagtcctga
      481 taaatatgag gctgtctcgt cagtgattca atacaactac tgggtatagt ttctatgatt
      541 ttgttctgtg gaaatggaaa acagcaacca gtcaccacca gcacttcttt aaacatgcca
      601 agtcacacgc aagccaacat tatagttccc tttgagcgag cagatgaagc tagcaaaaat
      661 attgatcact taggatgcat tactaacgtt gctatgtgtt aacgaacagg gagtgggtca
      721 tcagcataaa tatttatgca gtaggtttct tt
//
LOCUS       DAPOAV010000306          751 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.328, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000306 DAPOAV010000000
VERSION     DAPOAV010000306.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..751
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.328"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            144..710
                     /gene="slp"
                     /locus_tag="RN951_004733"
     CDS             144..710
                     /gene="slp"
                     /locus_tag="RN951_004733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312404.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein Slp"
                     /protein_id="HDX2529577.1"
                     /translation="MNMTKGALILSLSFLLAACSSIPQNIKGNNQPDIQKSFVAVHNQ
                     PGLYVGQQARFGGKVINVINGKTDTLLEIAVLPLDSYAKPDIEANYQGRLLARQSGFL
                     DPVNYRNHFVTILGTIQGEQPGFINKVPYNFLEVNMQGIQVWHLREVVNTTYNLWDYG
                     YGAFWPEPGWGAPYYTNAVSQVTPELVK"
BASE COUNT          230 a          158 c          164 g          199 t
ORIGIN      
        1 aaatcaatgg aattgaacta aacaaaaggg atataaacat cagacaggtt tacgttacta
       61 tcaggcatat cacctcagaa tcagatgaaa actataaaga aatatctatt atggctttaa
      121 tatttgttga taaggatagt aacatgaaca tgacaaaagg tgcactcatc ctcagccttt
      181 catttttgct tgccgcatgt agttcaattc cgcaaaatat caaaggcaat aaccaacctg
      241 atattcaaaa aagttttgtt gctgttcata accagccggg gttatatgtt ggtcaacaag
      301 cgcgctttgg tgggaaggtt atcaacgtta tcaatggcaa aacggatacg ttgttagaaa
      361 tcgctgtatt accgttggat agctatgcga agcctgatat tgaagccaac tatcagggcc
      421 gactgctcgc cagacaaagc ggcttccttg atccagtgaa ctatcgtaat cactttgtta
      481 ccatcctcgg taccattcag ggtgaacaac caggctttat caataaagtc ccgtataact
      541 tcctggaagt gaatatgcag ggcatccagg tgtggcattt gagagaagtg gttaatacca
      601 cctataacct gtgggattac ggctatggtg cattctggcc ggaaccgggc tggggtgcgc
      661 cttactacac caatgcggtg agtcaggtaa cacctgagct ggtcaaataa caccaccgaa
      721 agatgcagat gctttctcag catctgcatc a
//
LOCUS       DAPOAV010000307          746 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.329, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000307 DAPOAV010000000
VERSION     DAPOAV010000307.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..746
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.329"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..627)
                     /locus_tag="RN951_004734"
     CDS             complement(<1..627)
                     /locus_tag="RN951_004734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001704620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529578.1"
                     /translation="MIFRDSLRVLPYGRVDNDFFQIEERRSWNAGRYYWSNRRIFGYI
                     GITQSSNKELKDKSGREGFIRNQAARELKTIISNLLTELADRFFGSRSDDRKELLEQV
                     KREKELRKSAQQQARKSTQKSFSEALKNQTPVLDASLEAVKRLKTKLDKTDGSLDLNY
                     LKIIDSDLTNLDALRSEIKTPIKPPKLGMYEEKYRDYRDKFNEFSAYIL"
BASE COUNT          214 a          153 c          114 g          265 t
ORIGIN      
        1 tagaatatac gcagagaact cattaaattt atctctgtag tctctatatt tctcttcata
       61 cattccaagt tttggaggtt tgataggcgt tttaatttca ctgcgcaacg catctaagtt
      121 tgtaagatca ctgtctataa ttttaagata gtttaaatct aacgaaccat cagttttatc
      181 aagcttagtt ttcagccttt taacagcctc caaggaagca tcaagaactg gtgtctgatt
      241 cttcaaagct tctgaaaaac ttttttgtgt tgattttcga gcttgttgtt gagcagattt
      301 tcttaactct ttttcacgct taacttgttc taaaagctct ttacggtcat cagaacgtga
      361 accaaaaaat ctatcagcaa gttcagttaa caaattagat ataatagttt tcagttctct
      421 tgcagcctgg tttcttatga atccctctct ccccgactta tctttcagct ctttattact
      481 ggattgagta attccaatat aaccaaaaat ccttctatta gaccaataat atcgccctgc
      541 attccatgaa cgtctttctt ctatctggaa gaaatcatta tctactcgac cataaggtaa
      601 tactctcaag ctatccctaa aaatcattag tcctgcatac tttttggcct taagatcaaa
      661 gtgggaatgt tcacgttcag tatgtgatgt attttgtgaa aggaattcaa acgttcctat
      721 ctgaagctca aatgggccga cccctg
//
LOCUS       DAPOAV010000308          732 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.330, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000308 DAPOAV010000000
VERSION     DAPOAV010000308.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..732
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.330"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..>732)
                     /gene="intI1"
                     /locus_tag="RN951_004735"
     CDS             complement(<1..>732)
                     /gene="intI1"
                     /locus_tag="RN951_004735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="class 1 integron integrase IntI1"
                     /protein_id="HDX2529579.1"
                     /translation="WVRAFIRFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQAL
                     AALLFFYGKVLCTDLPWLQEIGRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLY
                     GTGMRISEGLQLRVKDLDFDHGTIIVREGKGSKDRALMLPESLAPSLREQLSRARAWW
                     LKDQAEGRSGVALPDALERKYPRAGHSWPWFWVFAQHTHSTDPRSGVVRRHHMYDQTF
                     QRAFKRAVEQAGITKPATPHTLRHS"
BASE COUNT          154 a          236 c          221 g          121 t
ORIGIN      
        1 aacgagtggc ggagggtgtg cggtgtggcg ggcttcgtga tgcctgcttg ttctacggca
       61 cgtttgaagg cgcgctgaaa ggtctggtca tacatgtgat ggcgacgcac gacaccgctc
      121 cgtggatcgg tcgaatgcgt gtgctgcgca aaaacccaga accacggcca ggaatgcccg
      181 gcgcgcggat acttccgctc aagggcgtcg ggaagcgcaa cgccgctgcg gccctcggcc
      241 tggtccttca gccaccatgc ccgtgcacgc gacagctgct cgcgcaggct gggtgccaag
      301 ctctcgggta acatcaaggc ccgatccttg gagcccttgc cctcccgcac gatgatcgtg
      361 ccgtgatcga aatccagatc cttgacccgc agttgcaaac cctcactgat ccgcatgccc
      421 gttccataca gaagctgggc gaacaaacga tgctcgcctt ccagaaaacc gaggatgcga
      481 accacttcat ccggggtcag caccaccggc aagcgccgcg acggccgagg tcttccgatc
      541 tcctgaagcc agggcagatc cgtgcacagc accttgccgt agaagaacag caaggccgcc
      601 aatgcctgac gatgcgtgga gaccgaaacc ttgcgctcgt tcgccagcca ggacagaaat
      661 gcctcgactt cgctgctgcc caaggttgcc gggtgacgca caccgtggaa acggatgaag
      721 gcacgaaccc ag
//
LOCUS       DAPOAV010000309          723 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.331, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000309 DAPOAV010000000
VERSION     DAPOAV010000309.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..723
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.331"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..577
                     /locus_tag="RN951_004736"
     CDS             <1..577
                     /locus_tag="RN951_004736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001581568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDX2529580.1"
                     /translation="DHFCIIDRQGRKRFRWITVGRLVKIKNQLLILQAMMQLPHSELI
                     IVGEGEERLTLQTFIDQNSLSERVTLLGKKDNVVDYYHDSDAFVLASDYEGFALVVAE
                     AMACGLPVVATDCGGPAEIIGNGQDFGITISVNDVHHLTAAMQQIESLDIEQRKGSGY
                     RARERVIEKFSAKKIVSQWEDIYLCIQKNRI"
BASE COUNT          242 a          118 c          160 g          203 t
ORIGIN      
        1 tgatcatttt tgtatcatcg atagacaggg caggaaacga tttcgctgga taacagttgg
       61 gcggcttgta aaaataaaaa accaactgtt gattttgcaa gctatgatgc agttgccaca
      121 tagtgaactc atcatagttg gagagggcga agaacggctt acattgcaaa catttatcga
      181 tcaaaattct ctcagcgagc gagttactct cttgggaaaa aaggataatg ttgttgatta
      241 ttaccatgat tccgatgcct ttgtgctggc ctctgactat gaaggttttg ctcttgtcgt
      301 tgccgaagct atggcatgtg gattaccagt ggtcgcaaca gattgtggtg ggccagcaga
      361 aattattgga aatggacagg attttggcat aacaatatcg gttaatgatg tacatcactt
      421 aactgcagcg atgcaacaga ttgaatcatt agatatcgaa caacgtaaag gaagcggcta
      481 tcgtgctcgg gaaagagtca ttgagaaatt ttctgctaaa aaaatcgtat ctcaatggga
      541 agatatatac ctgtgcatac agaaaaacag aatttagaac tcacctatga aaatagcatt
      601 aatcggtact acagcagaaa gtctaatcca attcagaaaa gaactgatta atttattaca
      661 taaaaatggc catgttgtat atgcatttgc aattgactat gatgatgtga caaaagaaaa
      721 agt
//
LOCUS       DAPOAV010000310          702 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.332, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000310 DAPOAV010000000
VERSION     DAPOAV010000310.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 702)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 702)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..702
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.332"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            257..592
                     /locus_tag="RN951_004737"
     CDS             257..592
                     /locus_tag="RN951_004737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phnA family protein"
                     /protein_id="HDX2529581.1"
                     /translation="MSLPHCPKCNSEYTYEDNGMYICPECAYEWNDAEPAQESDELIV
                     KDANGNLLADGDSVTIIKDLKVKGSSSMLKIGTKVKNIRLVEGDHNIDCKIDGFGPMK
                     LKSEFVKKN"
BASE COUNT          218 a          156 c          155 g          173 t
ORIGIN      
        1 acgtttaaaa cgtcagaaag ataaaaatat catgtgaatt aaaaaaagaa caagtagagc
       61 attaacatta tcttaaataa taaatagagg caaaaagatt attttctttt tgcgtttcct
      121 ttcaaatgaa aacgatcgtc gtctaaaatc agcagtaccc ccgacaaact cagggatttt
      181 gtgtataatt gcggcctttt tcggcaatct gccgtttttt ggcgcttttg ccctgctgac
      241 ttttgaggaa atccacatgt cattaccaca ctgcccaaaa tgcaactccg aatacaccta
      301 cgaagataac ggcatgtaca tctgcccgga atgtgcctac gaatggaacg acgcagaacc
      361 tgcacaggaa agcgacgagc tgatcgttaa agatgctaac ggcaatctgc tggctgacgg
      421 cgacagcgtt accatcatta aagatctgaa ggtgaaaggt agctcttcga tgctgaaaat
      481 tggcaccaaa gtgaaaaaca tccgcctggt tgaaggcgac cataacatcg attgcaaaat
      541 cgacggtttt ggtccgatga aactgaaatc tgagtttgtg aaaaagaact gattgtattg
      601 tgatcggtaa gccggataag gcgctcgcgc cgcatccggc aacggtgcca gatgcctgat
      661 gcgacgcttg cgcgtcttat caggcctaca aattcccgca cc
//
LOCUS       DAPOAV010000311          692 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.335, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000311 DAPOAV010000000
VERSION     DAPOAV010000311.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.335"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..588)
                     /gene="fimE"
                     /locus_tag="RN951_004738"
     CDS             complement(<1..588)
                     /gene="fimE"
                     /locus_tag="RN951_004738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418733.1"
                     /note="upgraded from regulatory protein to switch DNA
                     invertase; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria switch DNA invertase FimE"
                     /protein_id="HDX2529582.1"
                     /translation="MSKRRYLTGKEVQAMMQAVCYGATGARDYCLILLAYRHGMRISE
                     LLDLHYQDLDLNEGRINIRRLKNGFSTVHPLRFDEREAVERWTQERANWKGADRTDAI
                     FISRRGSRLSRQQAYRIIRDAGIEAGTVTQTHPHMLRHACGYELAERGADTRLIQDYL
                     GHRNIRHTVRYTASNAARFAGLWERNNLINEKLKRE"
BASE COUNT          201 a          174 c          142 g          175 t
ORIGIN      
        1 ttctcttttt aatttttcgt ttatgagatt atttctttcc cataatccgg caaaacgagc
       61 agcattactg gcggtataac gcacagtatg gcgaatattt cgatgcccga gataatcctg
      121 aattaaacgg gtatctgcac cacgctccgc cagttcataa ccgcaagcat gccttaacat
      181 atgaggatga gtctgcgtta cggttccagc ttcaataccg gcatcgcgaa taatgcgata
      241 ggcctgctgg cgagaaagcc gactcccgcg gcgagaaata aatatagcgt cggtccggtc
      301 agcgcctttc cagttagcac gttcctgggt ccagcgttcc acggcttcac gctcatcaaa
      361 acgtaacggg tgaacggtag aaaatccgtt cttcagtcgg cgaatattta ttcgaccttc
      421 attaaggtca aggtcctgat aatgcagatc aagcagttca ctaatacgca tcccatgccg
      481 atatgccaac agaataagac aataatctct ggctcccgtt gccccgtaac aaaccgcctg
      541 catcatggcc tgaacttctt taccggtaag ataacgacgt ttactcacaa tagtagtact
      601 cctgactgag atatatttga atgaatacct ataggaaacc tcaatcggtc aaaattagcc
      661 caatagataa aaagataacc acacacgaag tg
//
LOCUS       DAPOAV010000312          691 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.336, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000312 DAPOAV010000000
VERSION     DAPOAV010000312.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..691
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.336"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..611
                     /gene="ydeO"
                     /locus_tag="RN951_004739"
     CDS             <1..611
                     /gene="ydeO"
                     /locus_tag="RN951_004739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acid stress response transcriptional regulator
                     YdeO"
                     /protein_id="HDX2529583.1"
                     /translation="GFTENTIKKYLQCTNIQTVTVPVPAKFLRASNVPTGLLNEMIAY
                     LNSEERNHHNFSELLLFSCLSIFAACKGFITLLTNGVLSVSGKVRNIVNMKLAHPWKL
                     KDICDCLYISESLLKKKLKQEQTTFSQILLDARMQHAKNLIRVEGSVNKIAEQCGYAS
                     TSYFIYAFRKHFGNSPKRVSKEYRCQSHTGMNTGNTMNALAI"
BASE COUNT          210 a          139 c          139 g          203 t
ORIGIN      
        1 tcggatttac tgaaaatacc attaaaaaat atctacaatg cactaacatc cagacagtga
       61 cggtgcctgt tcctgcgaag tttttacgtg cttcaaatgt accgactgga ttgcttaatg
      121 aaatgattgc ttatctcaac tcggaagaac gcaatcatca taatttttca gaacttttgc
      181 ttttttcttg cctgtctatt tttgccgcat gcaaaggttt cattacacta ttaactaacg
      241 gtgtgctatc cgtttctggg aaagtgagaa atattgtcaa catgaagctg gcgcacccat
      301 ggaagctgaa agatatttgt gactgcctgt acatcagtga aagcctgttg aagaaaaaac
      361 ttaagcaaga gcaaacgaca ttctcacaga ttcttttaga tgcaagaatg cagcacgcaa
      421 aaaatttgat acgcgtagaa ggttcagtca ataaaattgc cgaacaatgt ggttatgcca
      481 gtacatctta ttttatttat gcgttccgca aacatttcgg caacagtccg aagagagttt
      541 ctaaggagta ccgttgtcaa agtcacacgg gtatgaatac gggcaacacg atgaatgctt
      601 tagctatttg attatttgct aacgagtagt caaccacaca cgctgcgtaa gaattaaatg
      661 gggcagccat tccctgcccc gcgttgtttt t
//
LOCUS       DAPOAV010000313          688 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.337, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000313 DAPOAV010000000
VERSION     DAPOAV010000313.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..688
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.337"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            89..673
                     /locus_tag="RN951_004740"
     CDS             89..673
                     /locus_tag="RN951_004740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX2529584.1"
                     /translation="MSKKLGFALSGLMLAMVAGTASADMDGGQLNISGLVVDNTCETR
                     VDGGNKDGLILLQTATVGEIDAGVLNDTVGAKAKPFSITVDCSKANPNPGSTAKMTFG
                     SVFFGNSKGTLNNDMSINNPSDGVNIALHNIDGSTIKQVQINNPGDVYTKALDATTKS
                     AVYDFKASYVRAVADQTATAGYVKTNTAYTITYQ"
BASE COUNT          194 a          148 c          143 g          203 t
ORIGIN      
        1 atctaacatt tgtttctcct atttgtgtca tgaatagtca ttcttcaaac atgtagtctg
       61 actaatggaa ttttattaaa ggatttttat gtctaaaaaa ttaggttttg ccctgtctgg
      121 tcttatgctg gcgatggttg caggtactgc ttctgctgat atggacggcg gtcagttaaa
      181 tatcagtggt ctggttgttg ataacacctg tgaaacccgc gttgacggcg gtaacaagga
      241 tggtctgatc ctgctgcaaa ccgcaaccgt tggtgaaatc gatgctggcg tactgaatga
      301 caccgttggc gctaaagcta aacctttcag catcaccgtt gactgcagca aagcaaatcc
      361 gaatccaggt agcacggcta aaatgacctt cggttctgtt ttctttggta acagcaaagg
      421 gactttgaac aacgacatgt ctattaacaa cccatctgac ggcgttaata tcgctctaca
      481 caatattgat ggttccacta tcaaacaggt tcaaattaac aaccctggcg atgtgtatac
      541 taaagccctg gatgcaacga caaaatctgc tgtttatgat tttaaagcgt cttacgttcg
      601 tgccgtcgca gaccaaacag caactgctgg ttatgtaaaa actaacactg catacaccat
      661 tacttatcag taagtattca ccagttaa
//
LOCUS       DAPOAV010000314          669 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.339, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000314 DAPOAV010000000
VERSION     DAPOAV010000314.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..669
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.339"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            111..479
                     /locus_tag="RN951_004741"
     CDS             111..479
                     /locus_tag="RN951_004741"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529585.1"
                     /translation="MFSYLKAMYHQSKIQAELKAQIHEQTTVNAICHHPESIEIIAVC
                     STDAYYRKRKDAAFLTTCSVLMRTLKDESVPMVLRKTAWRLLNERYQRIKLNQAYRIE
                     NFLLVADFEYALEEHDELAE"
BASE COUNT          211 a          135 c          144 g          179 t
ORIGIN      
        1 taagcgcatt ttttgcacag atggctaccg actgaacgta acgtgtgagt catgatcaga
       61 aatgtgttaa ctctaggaat tgacacgact tactgtttga tggggaaatc atgtttagct
      121 atctcaaggc tatgtatcat caatcaaaaa ttcaggctga actcaaggca cagatacatg
      181 aacaaactac ggttaatgct atctgtcatc accctgaatc aatcgagatc attgcggttt
      241 gttcgactga tgcgtattac cgaaaacgta aggacgctgc ttttctgaca acctgttctg
      301 tgctcatgcg tactttaaaa gatgaatccg taccgatggt actacggaaa acagcatggc
      361 gattattgaa cgaaagatac caacgaatta agttaaatca ggcttatagg atagaaaatt
      421 tcttgcttgt tgccgatttt gaatatgctc tcgaagaaca tgatgaacta gcagagtagt
      481 actagtgagg cgatgaatac cgacagttaa cgtgcatgtg acttaaacgt ccgattacgt
      541 acagcatgta gacaacatgt ccgaaagtaa gcaaaaccat taacggacag ccggatcatt
      601 tcgtacatcc cttacggtca ggggttcgcg ctcaatggaa cgaaatcacc cgttagctta
      661 aaacgctta
//
LOCUS       DAPOAV010000315          663 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.341, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000315 DAPOAV010000000
VERSION     DAPOAV010000315.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..663
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.341"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..>663
                     /locus_tag="RN951_004742"
     rRNA            <1..>663
                     /locus_tag="RN951_004742"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          154 a          146 c          222 g          141 t
ORIGIN      
        1 tggtgggtag tttgactggg gcggtctcct cctaaagagt aacggaggag cacgaaggtt
       61 ggctaatcct ggtcggacat caggaggtta gtgcaatggc ataagccagc ttgactgcga
      121 gcgtgacggc gcgagcaggt gcgaaagcag gtcatagtga tccggtggtt ctgaatggaa
      181 gggccatcgc tcaacggata aaaggtactc cggggataac aggctgatac cgcccaagag
      241 ttcatatcga cggcggtgtt tggcacctcg atgtcggctc atcacatcct ggggctgaag
      301 taggtcccaa gggtatggct gttcgccatt taaagtggta cgcgagctgg gtttagaacg
      361 tcgtgagaca gttcggtccc tatctgccgt gggcgctgga gaactgaggg gggctgctcc
      421 tagtacgaga ggaccggagt ggacgcatca ctggtgttcg ggttgtcatg ccaatggcac
      481 tgcccggtag ctaaatgcgg aagagataag tgctgaaagc atctaagcac gaaacttgcc
      541 ccgagatgag ttctccctga ctccttgaga gtcctgaagg aacgttgaag acgacgacgt
      601 tgataggccg ggtgtgtaag cgcagcgatg cgttgagcta accggtacta atgaaccgtg
      661 agg
//
LOCUS       DAPOAV010000316          649 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.342, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000316 DAPOAV010000000
VERSION     DAPOAV010000316.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..649
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.342"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            1..649
                     /locus_tag="RN951_004743"
                     /pseudo
     CDS             1..649
                     /locus_tag="RN951_004743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313048.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SopA family protein"
BASE COUNT          216 a           88 c          120 g          225 t
ORIGIN      
        1 aatatgtttc gtgaagtctc aatcagtaat gatactataa gtgtaaaatt ctacagaaat
       61 aaaaaaaatt gaatgcgctt gcaattttct gatggataaa gatgcgcagg ggtatatcga
      121 cctgtctgat ttggatttaa caagttgtca ttttaaaggt gacgttatat cgaaggtgtc
      181 ttttttatca tcaaatctac aacatgtaac attcgaatgt aaagaaattg gggattgcaa
      241 ttttactact gcaatagttg ataatgtcat atttagatgt cgacgtttac acaatgtgat
      301 ttttatcaaa gcgagtggtg aatgtgtcga tttcagcaaa aatattcttg atacagttga
      361 cttctcgcag agtcaacttg gtcatagtaa ttttcgcgaa tgtcagatta gaaattcaaa
      421 cttcgataat tgttatcttt acgcttcgca cttcaccaga gcagagtttc tgtctgccaa
      481 agaaatatca tttattaaat cgaatttgac agctgttatg tttgattatg tgcgaatgtc
      541 gacagggaat tttaaagatt gcattacaga acaattggaa ttaactattg attattcaga
      601 tatattttgg aatgaagatc tcgatggtta tatcaataac attataaaa
//
LOCUS       DAPOAV010000317          647 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.343, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000317 DAPOAV010000000
VERSION     DAPOAV010000317.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..647
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.343"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..>647)
                     /locus_tag="RN951_004744"
     CDS             complement(<1..>647)
                     /locus_tag="RN951_004744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4329 domain-containing protein"
                     /protein_id="HDX2529586.1"
                     /translation="SGLYYNRHRYYDPLQGRYITQDPMGLKGGWNLYQYPLNPLQQID
                     PMGLLQTWDDARSGACTGGVCGVLSRIIGPSKFDSTADAALDALKETQNRSLCNDMEY
                     SGIVCKDTNGKYFASKAETDNLRKESYPLKRKCPTGTDRVAAYHTHGADSHGDYVDEF
                     FSSSDKNLVRSKDNNLEAFYLATPDRRFEALNNKGEYIFIRNSVPGLSSVCIPYH"
BASE COUNT          191 a          150 c          100 g          206 t
ORIGIN      
        1 tcatgatacg gtatgcatac tgaactcaat cccgggacac tatttctgat aaaaatatat
       61 tctcctttat tattaagcgc ctcaaatcgt ctatcaggtg ttgcgagata aaatgcttca
      121 agattattat ctttacttct tacaagattt ttatcgctac ttgaaaaaaa ttcatcaaca
      181 taatcgccat gactatctgc accgtgagta tgataagcag caactctatc tgtacctgtg
      241 ggacattttc ttttcagagg atatgactcc tttcttaaat tatcagtttc tgccttagat
      301 gcaaaatatt ttccattagt atctttacag acaataccag agtattccat atcattacat
      361 agagatctat tctgcgtttc tttcaaagca tctaacgcag catctgcagt actatcaaat
      421 ttacttggtc ctattatacg tgaaagaaca ccacaaactc cccccgtaca tgctccagat
      481 ctggcatcat cccaagtctg caataatccc atagggtcaa tttgttgtag tggatttaaa
      541 ggatactgat ataaattcca tccccctttc aaccccatcg ggtcctgagt aatataccgc
      601 ccctgcaacg gatcgtagta ccggtgacgg ttatagtaca gccctga
//
LOCUS       DAPOAV010000318          645 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.344, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000318 DAPOAV010000000
VERSION     DAPOAV010000318.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..645
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.344"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..626
                     /gene="waaZ"
                     /locus_tag="RN951_004745"
     CDS             <1..626
                     /gene="waaZ"
                     /locus_tag="RN951_004745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="3-deoxy-D-manno-oct-2-ulosonate III transferase
                     WaaZ"
                     /protein_id="HDX2529587.1"
                     /translation="PYIYVLTDVRFLHQRRDDFYKFSQRSRYTIVNVDVYEHASEEDK
                     RYILQNCLVLRSFYRREKGGLIKKIKFNILSRIHKELLISVPFSKKGRLVGFCKDINL
                     GYCSCHTVVFAAIQIAYSLKYARIICSGLDLTGSCSRFYDEDKNPMPSELTRDLFKIL
                     PFFRFMRENIEDINIYNLSDDTAIQYDIIPYMKISEIEEPCVYEKIS"
BASE COUNT          189 a          109 c          116 g          231 t
ORIGIN      
        1 ttccctatat ttatgtactt accgatgttc gctttttaca tcaacggcgt gatgattttt
       61 ataaatttag ccagagaagt cgttatacca tcgtaaatgt tgacgtttat gaacatgctt
      121 ctgaagaaga taagcggtac atccttcaaa actgcctggt actacgttca ttttaccgca
      181 gagaaaaagg tggattgatc aagaagatca agtttaatat tttgagccga attcataaag
      241 agctcctgat ctctgtacct ttttctaaaa aaggtcgtct ggttggcttt tgcaaggata
      301 ttaacctcgg ttattgttca tgccataccg ttgtttttgc tgcaatccaa atagcctatt
      361 cgctgaagta tgctcgtatt atctgttcag gccttgattt aacgggtagc tgttcgcgtt
      421 tctatgatga agataagaat cctatgccct cagagttgac tcgggattta ttcaaaattt
      481 taccattttt ccgttttatg cgtgaaaata tagaagatat caatatttat aatttatccg
      541 acgatactgc aattcaatat gatattattc cctatatgaa aatatccgaa attgaagagc
      601 cgtgtgttta tgaaaaaata agctaatatt ttatatgtgt ttatt
//
LOCUS       DAPOAV010000319          626 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.346, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000319 DAPOAV010000000
VERSION     DAPOAV010000319.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..626
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.346"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            89..379
                     /locus_tag="RN951_004746"
     CDS             89..379
                     /locus_tag="RN951_004746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDX2529588.1"
                     /translation="MKLKIVAVVVTGLLAANVAHAAEVYNKDGNKLDLYGKVTALRYF
                     TDDKRDDGDKTYARLGFKGETQINDQMIGFGHWEYDFKGYNDEANGSRGKNL"
     gene            403..>626
                     /locus_tag="RN951_004747"
     CDS             403..>626
                     /locus_tag="RN951_004747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HDX2529589.1"
                     /translation="MITDLILHNHPRMKTITLNDNHIAHLNAKNTTKLEYLNLSNNNL
                     LPTNDIDQLISSKHLWHVLVNGINNDPLAQ"
BASE COUNT          224 a          116 c          109 g          177 t
ORIGIN      
        1 ttttaaaaac agtatgtcat ttataaatga cgccgtttaa aattcgttta gaaaatacgt
       61 ttaacgataa ttaaaaggat tctgttaaat gaaattaaaa atagttgcgg tggttgtaac
      121 tggtttgtta gctgcgaacg tagcacacgc tgccgaagtc tataacaagg atggtaataa
      181 actcgacctt tatggcaagg ttaccgctct acgttatttt actgatgata agcgtgacga
      241 tggtgataaa acttatgccc gtctcggctt taaaggagaa acgcaaatca atgatcaaat
      301 gattggtttt ggtcactggg aatatgattt taaaggctat aacgatgaag ccaacggctc
      361 gcgcggcaag aatctctgat tgagttaagt gcccatcaca atatgatcac tgaccttata
      421 ttacacaatc atcccaggat gaaaacaatc actttaaacg acaaccatat tgcacattta
      481 aacgccaaaa acactacaaa actggaatat ttaaacttaa gcaataacaa tttactgcca
      541 accaatgaca ttgatcaact aatatcatca aaacatcttt ggcatgtatt agttaacggc
      601 atcaacaatg atccacttgc acaaat
//
LOCUS       DAPOAV010000320          624 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.347, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000320 DAPOAV010000000
VERSION     DAPOAV010000320.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..624
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.347"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..>624)
                     /locus_tag="RN951_004748"
     CDS             complement(<1..>624)
                     /locus_tag="RN951_004748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001463032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDX2529590.1"
                     /translation="VGKTTQFRAVMSAVNMLPASERPRVVGLGPTHRAVGEMRSAGVD
                     AQTLASFLHDTQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVAS
                     GDTDQLQAIAPGQPFRLQQTRSAADVVIMKEIVRQTPELREAVYSLINRDVERALSGL
                     ESVKPSQVPRQEGAWAPEHSVTEFSHSQEAKLAEAQQKAMLKGETFPD"
BASE COUNT          107 a          221 c          171 g          125 t
ORIGIN      
        1 atccggaaaa gtctcacctt tcagcatcgc cttctgctgc gcttctgcca gtttcgcttc
       61 ctggctgtga ctgaactccg tcacggagtg ctccggtgcc catgcgccct cctgacgggg
      121 aacctgagac ggtttcacac tctcaagccc ggacagtgcc ctttccacat cccggttaat
      181 caggctgtat accgcctccc gcagttccgg cgtctgacgc acaatctcct tcatgatgac
      241 cacatcggca gcactgcgcg tctgctggag acggaaaggc tgaccgggcg cgatggcctg
      301 cagctggtcc gtgtcaccac tggccacggc acgaccgcca ccggccgcaa tcagggcgta
      361 tgcccgtgcc atgtcggtat tgcccaccat tgagctctca tcgagcagga acagcgtgtt
      421 gctgaaatcc ggcgtttctc cgctgcgctg ctgcagctgc gtgtcatgca gaaaggacgc
      481 cagcgtctgt gcatccacgc cggcgctgcg catctcaccg accgcacggt gcgtgggccc
      541 cagccccaca actcggggac gctcactcgc cggcagcatg ttcacggctg acatcaccgc
      601 ccggaactgt gtggtcttac ccac
//
LOCUS       DAPOAV010000321          624 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.348, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000321 DAPOAV010000000
VERSION     DAPOAV010000321.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..624
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.348"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..>624
                     /locus_tag="RN951_004749"
     CDS             <1..>624
                     /locus_tag="RN951_004749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001463032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDX2529591.1"
                     /translation="VGKTTQFRAVMSAVNMLPESERPRVVGLGPTHRAVGEMRSAGVD
                     AQTLASFLHDTQLQQRSGETPDFSNTLFLLDESSMVGNTDMARAYALIAAGGGRAVAS
                     GDTDQLQAIAPGQPFRLQQTRSAADVAIMKEIVRQTPELREAVYSLINRDVEKALSGL
                     ESVKPSQVPRLEGAWAPEHSVTEFSHSQEAKLAEAQQKAMLKGEAFPD"
BASE COUNT          126 a          173 c          221 g          104 t
ORIGIN      
        1 gtgggtaaga ccacacagtt ccgggcggtg atgtcagccg tgaacatgct gccggagagt
       61 gagcgtcccc gtgtcgttgg gctggggccc acgcaccgtg cggtcgggga gatgcgcagc
      121 gccggcgtgg atgcacagac actggcgtcc tttctgcatg acacgcagct gcagcagcgc
      181 agcggagaaa cgccggattt cagcaacacg ctgttcctgc tcgatgagag ctcaatggtg
      241 ggcaataccg acatggcacg ggcatacgcc ctgattgcgg ccggtggcgg tcgtgctgtg
      301 gccagcggtg acacggacca gctgcaggcc atcgcgcccg gtcagccttt ccgtctccag
      361 cagacgcgca gtgctgccga tgtggccatc atgaaggaga ttgtgcgtca gacgccggaa
      421 ctgcgggagg cggtatacag cctgattaac cgggatgtgg aaaaggcact gtccgggctt
      481 gagagtgtga aaccgtctca ggtgccacgt ctggagggcg catgggcacc ggagcactcc
      541 gtgacggagt tcagtcacag ccaggaagcg aaactggcag aagcgcagca gaaggcgatg
      601 ctgaaaggcg aggctttccc ggat
//
LOCUS       DAPOAV010000322          620 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.349, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000322 DAPOAV010000000
VERSION     DAPOAV010000322.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..620
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.349"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(1..150)
                     /locus_tag="RN951_004750"
     CDS             complement(1..150)
                     /locus_tag="RN951_004750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001300273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HDX2529592.1"
                     /translation="MTKYALIGLLAVCATVLCFSLIFRERLCELNIHRGNTVVQVTLA
                     YEARK"
     gene            complement(394..576)
                     /locus_tag="RN951_004751"
     CDS             complement(394..576)
                     /locus_tag="RN951_004751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529593.1"
                     /translation="MMARKFGKQLIVAVSEKDAIKLKDNFDIIGMLSYGKENFIAMSH
                     TKSELTGGKRRYRIKN"
BASE COUNT          168 a          163 c          103 g          186 t
ORIGIN      
        1 ttacttccgt gcttcgtagg ccagagttac ctgcaccact gtatttcccc tgtgaatatt
       61 cagttcacat aaccgttccc tgaatatcag tgaaaaacac aacaccgtgg cgcacacggc
      121 gagcaacccg ataagggcat atttcgtcat aaactttgac ctccctgcaa ggaagaggct
      181 acaatcagta gtgttaaggt acttcatgca gacctcacga gttaatggat taacgagtgg
      241 ggtcttcgca tttctggtac ctgcgtcttg cctgaaccag aaaggctcag acacccgccg
      301 cgataatacc acattccctg ttgctgacta ttaccttcat ttcccgcttt ttactaccga
      361 aactccagcc aataagtatg ctttttattt atatcaattt ttaatccggt accgacgttt
      421 ccctccagtt aactcgcttt tcgtatgact catggcaata aaattttctt taccatatga
      481 caacatccca ataatatcaa aattgtcttt taatttgatg gcatcctttt cacttacagc
      541 gacaataagt tgtttaccaa attttctggc catcattgca aactgtgata ctgctgatcc
      601 accacctaaa tcaggccacc
//
LOCUS       DAPOAV010000323          610 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.350, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000323 DAPOAV010000000
VERSION     DAPOAV010000323.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..610
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.350"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..473
                     /gene="agaB"
                     /locus_tag="RN951_004752"
     CDS             <1..473
                     /gene="agaB"
                     /locus_tag="RN951_004752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIB"
                     /protein_id="HDX2529594.1"
                     /translation="SPNILLTRIDNRLVHGQVGVTWTSTIGANLLVVVDDVVANDDIQ
                     QKLMGITAETYGFGIRFFTIEKTINVIGKAAPHQKIFLICRTPQTVRKLVEGGIDLKD
                     VNVGNMHFSEGKKQISSKVYVDDQDLTDLRFIKQRGVNVFIQDVPGDQKEQIPD"
     gene            512..>610
                     /locus_tag="RN951_004753"
     CDS             512..>610
                     /locus_tag="RN951_004753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417608.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates concomitant with their translocation across the
                     cell membrane;protein IIA transfers a phosphoryl group to
                     IIB which then transfers the phosphoryl group to the
                     sugar; IIC forms the translocation channel for the sugar
                     uptake; involved in N-acetylgalactosamine transport;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIC"
                     /protein_id="HDX2529595.1"
                     /translation="MHEITLLQGLSLAALVFVLGIDFWLEALFLFRP"
BASE COUNT          172 a          128 c          135 g          175 t
ORIGIN      
        1 ccagtccaaa tattctctta acccgtattg ataaccgtct ggttcacggt caggttggcg
       61 tgacctggac atccaccatc ggtgcaaatc tgctggtagt cgtggatgat gttgtcgcta
      121 acgatgatat tcaacagaaa ttaatgggta ttaccgcgga aacctacggc tttggcattc
      181 gtttctttac tatcgaaaaa accattaacg tcatcggcaa agctgcacca catcagaaga
      241 tcttcctgat ttgccgtacg ccacaaacgg tacgtaaatt ggtagaaggt ggtattgacc
      301 tgaaagatgt caacgtcggc aatatgcatt tctcggaagg gaaaaagcaa atcagcagta
      361 aagtttatgt cgatgaccag gatctcacgg acttacgttt tattaaacaa cgtggcgtga
      421 atgttttcat tcaggacgtc cctggcgatc aaaaagaaca aatccctgac taaatctaaa
      481 atcgccttaa tattggtttg aggtaataaa aatgcatgaa ataaccctac ttcagggatt
      541 atccctggcg gcgttagttt ttgttctggg gattgatttt tggctggaag ccttattttt
      601 attccgcccg
//
LOCUS       DAPOAV010000324          605 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.351, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000324 DAPOAV010000000
VERSION     DAPOAV010000324.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..605
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.351"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..>605
                     /locus_tag="RN951_004754"
     CDS             <1..>605
                     /locus_tag="RN951_004754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529596.1"
                     /translation="TVWMQISSTLKGALDINSLIIDYDNEDVQSYWEDVVLPNLNDNG
                     NKALTRDETIAYIKDSKPCRRIKRLIHDDAVLEDQKDKNFIAKMIAEYAVSRNAIISS
                     NTSGNVIRGDESGVKWIQCGNIFVSLFHKVQDDHENDGDRIWQTLNDSLIEWKPSYYQ
                     LIKSEIQNAIEAEALSFVNHLANDHYGQAAWLNEILKSDSP"
BASE COUNT          213 a           91 c          124 g          177 t
ORIGIN      
        1 aacggtttgg atgcagatat catcgactct caaaggtgct ctggatatca acagcttgat
       61 cattgactac gataatgaag atgtccaaag ttattgggaa gacgttgtat taccgaactt
      121 aaatgataat ggtaataaag ctctcacaag agatgaaaca atagcctata ttaaagacag
      181 taagccttgt agaagaatta aaagattaat acatgatgat gctgtgttgg aggatcaaaa
      241 ggataaaaac ttcattgcaa aaatgattgc agaatatgct gtgtctagaa atgcaattat
      301 ttctagcaac acatctggca atgtcattcg gggtgatgaa agcggagtaa aatggattca
      361 atgtggtaat atctttgtct ccctatttca taaggttcaa gatgatcatg aaaacgatgg
      421 agataggatt tggcaaactc tcaatgattc tctcattgaa tggaaaccat cttattatca
      481 gttaataaaa tctgaaattc agaatgcaat cgaagctgag gctttatctt ttgtaaatca
      541 tttggctaac gatcattacg gtcaagctgc gtggttaaat gagatattaa aatcagactc
      601 gccag
//
LOCUS       DAPOAV010000325          592 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.353, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000325 DAPOAV010000000
VERSION     DAPOAV010000325.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..592
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.353"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
BASE COUNT          196 a           93 c          132 g          171 t
ORIGIN      
        1 tttacaagtc ttttgaatac catttccaga atctttaatg tcctcaaaag caatcaaatt
       61 ataaaccttt gtatcaggtc tgcatatgtg gagcaattga gcgcgagtcg ctaatgagag
      121 atgtccgtat gttttgttga ttgtaggtat agaaggggaa gcgacgtaat accaacccga
      181 agcgaagttc taaacagata agtgaagttg tatatggaat agctatgaga aagccctacc
      241 tttgttgaaa gcataaatag gggataacaa tacattaatc tgcatgaacg aatctggggg
      301 tgtcgtaggg tgtcctacat tggaaacgat gtagagcttt aagccagatc aacttgggtg
      361 aagtcatatt tttcatcttg gttttcgcca atcttgatag attttcaaca aaataagttg
      421 aaaatttcag gaggcgaagc cttgggtgaa gtcccatttt ccggggcgaa cacaaggcag
      481 tatatagctc tcagtaaagc taagtttatt tatagtaaag gtgccttgtt ttatatggca
      541 ctaataaaat ataaagcaga gctagatcaa aaaaactata aaacgagggc ta
//
LOCUS       DAPOAV010000326          589 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.354, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000326 DAPOAV010000000
VERSION     DAPOAV010000326.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..589
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.354"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..557
                     /locus_tag="RN951_004755"
     CDS             <1..557
                     /locus_tag="RN951_004755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HDX2529597.1"
                     /translation="IVLQWDEMIRTAGSLKLGKVQASVLVRSLLKSERPSGLTQAIIE
                     VGRINKTLYLLNYIDDEDYRRRILTQLNRGESRHAVARAICHGQKGEIRKRYTDGQED
                     QLGALGLVTNAVVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHINMLGHYSF
                     TLAELVTKGHLRPLKEASEAENVA"
BASE COUNT          158 a          146 c          154 g          131 t
ORIGIN      
        1 aaatagtcct tcagtgggac gaaatgatcc ggaccgctgg ctccctgaag ctgggcaaag
       61 tacaggcttc agtgctggtc cgttcattgc tgaaaagtga acgtccttcc ggactgactc
      121 aggcaatcat tgaagtgggg cgcatcaaca aaacgctgta tctgcttaat tatattgatg
      181 atgaagatta ccgccggcgc attctgaccc agcttaatcg gggagaaagt cgccatgccg
      241 ttgccagagc catctgtcac ggtcaaaaag gtgagataag aaaacgatat accgacggtc
      301 aggaagatca actgggcgca ctggggctgg tcactaacgc cgtcgtgtta tggaacacta
      361 tttatatgca ggcagccctg gatcatctcc gggcgcaggg tgaaacactg aatgatgaag
      421 atatcgcacg cctctccccg ctttgccacg gacatatcaa tatgctcggc cattattcct
      481 tcacgctggc agaactggtg accaaaggac atctgagacc attaaaagag gcgtcagagg
      541 cagaaaacgt tgcttaacgt gagttttcgt tccactgagc gtcagaccc
//
LOCUS       DAPOAV010000327          570 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.355, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000327 DAPOAV010000000
VERSION     DAPOAV010000327.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..570
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.355"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            43..>570
                     /locus_tag="RN951_004756"
     CDS             43..>570
                     /locus_tag="RN951_004756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="HDX2529598.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDH
                     STIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTV
                     DFYLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDV
                     EHRQIKYRNNVIECDH"
BASE COUNT          132 a          154 c          153 g          131 t
ORIGIN      
        1 tggtgataaa cttatcatcc ccttttgctg atggagctgc acatgaaccc attcaaaggc
       61 cggcattttc agcgtgacat cattctgtgg gccgtacgct ggtactgcaa atacggcatc
      121 agttaccgtg agctgcagga gatgctggct gaacgcggag tgaatgtcga tcactccacg
      181 atttaccgct gggttcagcg ttatgcgcct gaaatggaaa aacggctgcg ctggtactgg
      241 cgtaaccctt ccgatctttg cccgtggcac atggatgaaa cctacgtgaa ggtcaatggc
      301 cgctgggcgt atctgtaccg ggccgtcgac agccggggcc gcactgtcga tttttatctc
      361 tcctcccgtc gtaacagcaa agctgcatac cggtttctgg gtaaaatcct caacaacgtg
      421 aagaagtggc agatcccgcg attcatcaac acggataaag cgcccgccta tggtcgcgcg
      481 cttgctctgc tcaaacgcga aggccggtgc ccgtctgacg ttgaacaccg acagattaag
      541 taccggaaca acgtgattga atgcgatcat
//
LOCUS       DAPOAV010000328          548 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.358, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000328 DAPOAV010000000
VERSION     DAPOAV010000328.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.358"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            29..>548
                     /locus_tag="RN951_004757"
     CDS             29..>548
                     /locus_tag="RN951_004757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415458.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDX2529599.1"
                     /translation="MKKSVLTAFITVVCATSSVMAADDNAITDGSVTFNGKVIAPACT
                     LVAATKDSVVTLPDVSATKLQTNGQVSGVQIDVPIELKDCDTTVTKNATFTFNGTADT
                     TQITAFANQASSDAATNVALQMYMNDGTTAITPDTETGNILLQDGDQTLTFKVDYIAT
                     GKATSGNVNAVTN"
BASE COUNT          164 a          103 c          133 g          148 t
ORIGIN      
        1 tatttacgaa gagatcagga tgataacgat gaaaaaaagt gtattgacgg cgtttataac
       61 tgtggtatgt gcaacgtcca gcgttatggc tgctgatgat aatgctatca cggatggctc
      121 agtaacattt aatggtaaag ttattgctcc agcttgtacc ctggtagctg cgacgaaaga
      181 ttccgtggtg actttgccag atgttagtgc cacgaagttg caaaccaatg gtcaggtttc
      241 tggcgtgcaa attgatgtgc caattgaatt aaaagattgt gatactaccg taacaaaaaa
      301 tgcaacgttc acctttaatg gcactgcgga tactactcag attacagcgt ttgctaacca
      361 ggcctcatct gatgctgcta caaacgtggc cctgcaaatg tatatgaatg atggtacaac
      421 ggccatcacg ccagacacag aaaccgggaa cattttgttg caggatggag atcagacgtt
      481 gacttttaaa gttgattata tcgctacggg gaaagcgact tcaggtaatg tgaatgcggt
      541 aacaaatt
//
LOCUS       DAPOAV010000329          520 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.359, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000329 DAPOAV010000000
VERSION     DAPOAV010000329.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..520
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.359"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..121)
                     /locus_tag="RN951_004758"
     CDS             complement(<1..121)
                     /locus_tag="RN951_004758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529600.1"
                     /translation="MSHAVDGTYIKAQQDKMVNSSLCKKASVDTYFNVMEVNLI"
     gene            139..330
                     /locus_tag="RN951_004759"
     CDS             139..330
                     /locus_tag="RN951_004759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2633 family protein"
                     /protein_id="HDX2529601.1"
                     /translation="MSQATSMRKRHRFNSRMTRIVLLISFIFFFGRFIYSSVGAWQHH
                     QSKKEAQQSTLSVESPVQR"
BASE COUNT          142 a          119 c           89 g          170 t
ORIGIN      
        1 taattaaatt aacttccata acattaaaat atgtatccac tgacgctttt ttacataacg
       61 aagaattgac cattttgtcc tgttgtgcct taatgtaagt accgtccaca gcgtgggaca
      121 tacttcaagg aaccttttgt gagtcaggca accagtatgc gaaaacgaca ccgatttaac
      181 agtcgcatga cccgtatcgt actgctcatc agctttatct tcttctttgg ccgttttatc
      241 tactcgtccg tcggtgcctg gcagcaccat cagagcaaaa aagaagctca gcaatccaca
      301 ctctccgtcg aatcaccggt acaacgttag cggttacctt ctccactttc acagaaccta
      361 acggcacttc gctgtcggat gcttttgctc tttggaatta tcaaagcggc agatattctt
      421 tcatcttaaa ttttacgtct ttgtcctgac tgatgtttat cctgtttggc tgcgaaataa
      481 atataaaatt aatatatatg ttgtaatgat atatttttat
//
LOCUS       DAPOAV010000330          512 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.360, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000330 DAPOAV010000000
VERSION     DAPOAV010000330.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..512
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.360"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..>512
                     /locus_tag="RN951_004760"
     CDS             <1..>512
                     /locus_tag="RN951_004760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS2 family transposase"
                     /protein_id="HDX2529602.1"
                     /translation="RWCSDGFEFCCDNGERLRVTFALDCCDREALHWAVTTGGFNSET
                     VQDVMLGAVERRFGNDLPSSPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRSPES
                     NGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREYLRQ
                     RACNGLSDNR"
BASE COUNT          124 a          119 c          164 g          105 t
ORIGIN      
        1 cgatggtgct ctgacgggtt cgagttctgc tgtgataacg gagagagact gcgtgtcacg
       61 ttcgcgctgg actgctgtga tcgtgaggca ctgcactggg cggtcactac cggcggcttc
      121 aacagtgaaa cagtacagga cgtcatgctg ggagcggtgg aacgccgctt cggcaacgat
      181 cttccgtcgt ctccagtgga gtggctgacg gataatggtt catgctaccg ggctaatgaa
      241 acacgccagt tcgcccggat gttgggactt gaaccgaaga acacggcggt gcggagtccg
      301 gagagtaacg gaatagcaga gagcttcgtg aaaacgataa agcgtgacta catcagtatc
      361 atgcccaaac cagacgggtt aacggcagca aagaaccttg cagaggcgtt cgagcattat
      421 aacgaatggc atccgcatag tgcgctgggt tatcgctcgc cacgggaata tctgcggcag
      481 cgggcttgta atgggttaag tgataacaga tg
//
LOCUS       DAPOAV010000331          494 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.363, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000331 DAPOAV010000000
VERSION     DAPOAV010000331.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.363"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..>494)
                     /locus_tag="RN951_004761"
     CDS             complement(<1..>494)
                     /locus_tag="RN951_004761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004151156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDX2529603.1"
                     /translation="PTYNGGELWKTTVFSIKKHTPKETLVQVIDSSSTDGTDSVALNA
                     GFELLSIPGRDFNHGGTRNLAVEMHHSQYELVIFLTQDAIPQMGFLEKIIDVFKDERV
                     VCAYGRQIPHDDANPLAQHARKFNYTDKSYICSQEDVSRMGLKTVFMSNSFSAYRLSI
                     FNEIG"
BASE COUNT          146 a          109 c           85 g          154 t
ORIGIN      
        1 ccaatttcat taaatataga taatctatac gcggaaaatg agtttgacat aaaaactgtc
       61 tttaaaccca ttctcgatac atcttcctga ctacaaatgt agctcttgtc agtgtagtta
      121 aattttcttg catgctgagc aagcgggtta gcatcatcat gaggaatttg tcttccatac
      181 gcacacacta cacgttcatc cttaaataca tcaataattt tttcgaggaa tcccatttgt
      241 ggtattgcat cttgtgtcaa gaaaatgacc agttcatatt gactatgatg catttcaaca
      301 gccaaattcc gcgttcctcc atggttaaaa tcgcggcccg ggatactcag cagctcaaaa
      361 cctgcattga gagcaacact gtcggtacca tcggtgctac tcgagtcgat aacctgaact
      421 agagtttctt ttggagtatg tttcttaata gaaaaaacag tcgttttcca taactcccca
      481 ccattatatg ttgg
//
LOCUS       DAPOAV010000332          479 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.365, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000332 DAPOAV010000000
VERSION     DAPOAV010000332.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.365"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
BASE COUNT          143 a           88 c          113 g          135 t
ORIGIN      
        1 caaggaaaga tttgcaagct aactcagtgg gtgtggtgaa aataagtgtt tacccgccat
       61 caggctgagc ataattctca tcatgaaata tgtttcctgg tttgtggctt gtaactggtc
      121 acttctgaag tcgatctgga gaggcttgtt gatgctggtg ttttcaggat gatgtttcag
      181 atagtttgtt tgccgtatcg cccggcgaat agctgtgatt gaggaaggtt taagtcgtag
      241 taaccaaagc catatttacc aacgaatgta gatgaaaaaa tcatctcctg cgttccccca
      301 tatctccagg ataaaaagga atgtaacaat ctcatggcct aaactgacga accagccagg
      361 aataatcgct agggacctaa gaattagcat gataatagcc actaagaaat tactgcgttc
      421 catgaaatag ccattttgtg gcaaatggag ttgactaata atgtcatatg tgagacggc
//
LOCUS       DAPOAV010000333          477 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.366, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000333 DAPOAV010000000
VERSION     DAPOAV010000333.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.366"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..137)
                     /locus_tag="RN951_004762"
     CDS             complement(<1..137)
                     /locus_tag="RN951_004762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component-system connector protein YmgA"
                     /protein_id="HDX2529604.1"
                     /translation="MKTSDNERIKYEITGQAVLQILRMKINFSLQTLIKQLLVMKSAE
                     E"
     gene            complement(180..416)
                     /locus_tag="RN951_004763"
     CDS             complement(180..416)
                     /locus_tag="RN951_004763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component-system connector protein YcgZ"
                     /protein_id="HDX2529605.1"
                     /translation="MHQNSVTLDSAGAITRYFAKANLHTQQETLGEIVTEILKDGRNL
                     SRKSLCAKLLCRLEHATGEEEQKHYNALIGLLFE"
BASE COUNT          138 a          105 c           82 g          152 t
ORIGIN      
        1 tcttcctcag ccgatttcat tacgagtaat tgcttaataa gagtctgcaa tgaaaaattt
       61 atcttcatgc gcagtatctg gagcaccgcc tggccagtaa tttcatattt tatacgttca
      121 ttatcagatg tcttcataac gacttcatag ctaacctgtt aaataatcag gctgttgcat
      181 tattcaaaaa gcaacccaat tagtgcatta taatgtttct gttcctcttc ccccgtcgcg
      241 tgttccagtc ggcaaagaag tttggcacaa agcgactttc gactcagatt acgtccatct
      301 ttcaaaatct cagtcacaat ttccccgaga gtttcctgct gagtatgcaa gttagctttt
      361 gcaaagtaac gagtgattgc tcccgcagaa tctaaagtca ctgaattttg atgcatgcta
      421 cgcctctgtt aaaaatgtta atcaatgtta agtgaagtaa caatagcaaa cttgtac
//
LOCUS       DAPOAV010000334          476 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.367, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000334 DAPOAV010000000
VERSION     DAPOAV010000334.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.367"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..>476
                     /locus_tag="RN951_004764"
     CDS             <1..>476
                     /locus_tag="RN951_004764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type VI secretion system tube protein Hcp"
                     /protein_id="HDX2529606.1"
                     /translation="KYYYIQLRGAFLSAIHHQIIENQLDTETITISYEFILCQHLIAN
                     TEFSYLALPENYNRLFLPNSKNQTNNRFKTLNSKAIGRLLAAGGVYNGNIEGFRDTAE
                     KLGGDAIKGYDQILNEKTAGIAIATASILLTKRSNVDTYTEINSYLGKLRGQQKLL"
BASE COUNT          179 a           85 c           81 g          131 t
ORIGIN      
        1 aaagtattat tatatacaac taagaggcgc ttttttatcg gctattcatc accagatcat
       61 tgaaaaccaa ctggatacag aaacaataac tattagttat gaatttatcc tctgtcaaca
      121 tcttatcgca aataccgagt tcagctattt ggcactccct gaaaattata accgtttgtt
      181 tttaccaaat tcaaaaaacc aaacaaataa tcgtttcaaa acgttaaaca gcaaagctat
      241 tggcaggcta cttgctgctg gtggcgtata caatgggaac attgaaggat tcagagatac
      301 tgcggaaaaa ctgggtggag atgcaataaa aggctatgat caaatactaa atgaaaaaac
      361 agcgggcata gcgatagcaa cagcatctat tcttttaaca aagcgttcta atgttgatac
      421 atatacagaa ataaatagtt acttaggcaa acttagaggt caacaaaaac ttcttg
//
LOCUS       DAPOAV010000335          472 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.368, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000335 DAPOAV010000000
VERSION     DAPOAV010000335.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.368"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            61..465
                     /locus_tag="RN951_004765"
     CDS             61..465
                     /locus_tag="RN951_004765"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HDX2529607.1"
                     /translation="MKSLTAVRKKSPNYPVEFKIKMVELSHRPEISVAQLAREHGIND
                     NLLFKWRQYWREGKLRPPSTTENNVPELLPITLDAEDVVPTTSPRSQPVAAATPESLN
                     ISCEVTFRHGSLRLNGAISENILNLLIRELKR"
BASE COUNT          136 a          128 c          103 g          105 t
ORIGIN      
        1 tctggcagat cctgaaattc ctgagagaat agtggacacc aaatatggtg gacgcaatcc
       61 atgaaatcat taaccgcagt gcgtaaaaaa agccctaatt atcccgttga gttcaaaatc
      121 aaaatggttg aactctcgca tcgaccagag atctccgtag cgcaactcgc tcgtgagcat
      181 gggatcaacg ataatttgct gttcaagtgg cgccagtact ggcgcgaagg aaaactacgt
      241 cctccttcaa caacagaaaa caacgtgcct gagctgctcc cgataacact tgatgccgaa
      301 gatgttgtcc ctacaacctc cccccggtca caacctgtag ctgctgcgac acctgaatca
      361 ctcaatatca gctgtgaagt gacgttccgg cacggatcac tccgtctgaa tggtgccatc
      421 agcgaaaata tcctgaacct gctgatacgg gagctcaaac gttgatccca tt
//
LOCUS       DAPOAV010000336          469 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.369, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000336 DAPOAV010000000
VERSION     DAPOAV010000336.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.369"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            142..>469
                     /locus_tag="RN951_004766"
     CDS             142..>469
                     /locus_tag="RN951_004766"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDX2529608.1"
                     /translation="MDRAVREVFDFVEDNLRFKYVQLGKAYIDLLRQALIENNQEKKS
                     EEIYDFPLSLELGVSSIAGQVFIELGLSRITASYLENIIPNSNPSVSAAKEWLRNNDY
                     DSLKLPL"
BASE COUNT          166 a           83 c           84 g          136 t
ORIGIN      
        1 catccttaac cataacacat ctaaattttc taactatcta acttcaattg ctttgaattg
       61 gatgaggggt aaatctctgc cggagataat ctctctctcc ataaataaga aaaaagaaaa
      121 aaatccacta ggcctgtaaa tgtggacaga gctgtaagag aggtttttga tttcgtagaa
      181 gataacttgc gattcaaata tgtgcaactt ggcaaggcat atattgactt attgcgccaa
      241 gctttaattg aaaataacca agaaaaaaaa tccgaagaaa tctatgattt tccattatca
      301 cttgaactag gagtttcatc tatcgcaggg caagtattca tcgaactagg gttatctaga
      361 attacagcat cgtatctaga gaatatcatt ccaaactcaa acccttcggt aagtgcggcg
      421 aaggaatggt taaggaataa tgattatgat tccttaaaat taccgctag
//
LOCUS       DAPOAV010000337          467 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.370, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000337 DAPOAV010000000
VERSION     DAPOAV010000337.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.370"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..>467
                     /locus_tag="RN951_004767"
     CDS             <1..>467
                     /locus_tag="RN951_004767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001463032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529609.1"
                     /translation="IVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELG
                     KEQVMVPVLNTANIRDGELRRLSTWENNPDALALVDSVYHRIAGISKDDGLITLEDAE
                     GNTRLISPREAVAEGVTLYTPDKIRVGTGDRMRFTKSDRERGYVANSVWTVTA"
BASE COUNT          107 a          120 c          161 g           79 t
ORIGIN      
        1 ccattgtccg cgactatacc ggcaggacac cggaagcacg ggagcagacg ctgattgtca
       61 cgcacctgaa tgaggaccgg cgcgtactga acagcatgat tcatgatgca cgggaaaagg
      121 ccggtgagct ggggaaagag caggtcatgg tgcctgtcct gaacacagcg aatatacgtg
      181 acggggagct gcgtcgtctc tccacctggg agaataaccc ggatgccctt gccctggtgg
      241 atagtgtgta tcaccggatt gccggtatca gcaaggatga cgggctgata accctggagg
      301 atgcggaagg taacacgcgg ctgatttcgc cccgggaggc ggtggctgaa ggtgtcacac
      361 tgtacacccc ggacaaaatc cgggtgggga ccggcgaccg gatgcgcttc acgaagagtg
      421 accgggagcg cggttatgtg gccaacagcg tctggacggt gacagcg
//
LOCUS       DAPOAV010000338          438 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.372, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000338 DAPOAV010000000
VERSION     DAPOAV010000338.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.372"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(160..>438)
                     /locus_tag="RN951_004768"
     CDS             complement(160..>438)
                     /locus_tag="RN951_004768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDX2529610.1"
                     /translation="CGVPVISTDVGVVKDAFGEMQKEWILPVRSKDTLIDKLRDFYHK
                     RNSVVKCLSSENLQQIKKWDWKVKSENFRTFFDKVLESKKHSEISNKM"
BASE COUNT          128 a           98 c           68 g          144 t
ORIGIN      
        1 ttcaatgttg agcgccaggt tgcgccccat tactgccata ccgacgacgc cgatctgttg
       61 cttagacatt acatactcct gtcaggtgta gataccacga gcttgttaag ttgcgataat
      121 gataaaaaaa ctaggaccag ggatcaaatg atatcttgat cacattttat tgcttatctc
      181 gctgtgcttt ttagattcta gtactttgtc gaaaaaagtc cgaaagttct cagacttaac
      241 tttccaatcc cattttttta tttgttgcaa attttctgaa gatagacatt ttaccactga
      301 attacgctta tgataaaaat ctctaagttt atctatcaaa gtatccttgc ttctaactgg
      361 taaaatccat tctttttgca tctcaccaaa agcatctttg accacaccaa catcagtact
      421 tatcacggga acgccaca
//
LOCUS       DAPOAV010000339          433 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.373, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000339 DAPOAV010000000
VERSION     DAPOAV010000339.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.373"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..>433
                     /locus_tag="RN951_004769"
     rRNA            <1..>433
                     /locus_tag="RN951_004769"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          122 a           96 c          133 g           82 t
ORIGIN      
        1 ttactgcgaa ggggggacgg agaaggctat gttggccggg cgacggttgt cccggtttaa
       61 gcgtgtaggc tggttttcca ggcaaatccg gaaaatcaag gctgaggcgt gatgacgagg
      121 cactacggtg ctgaagcaac aaatgccctg cttccaggaa aagcctctaa gcatcaggta
      181 acatcaaatc gtaccccaaa ccgacacagg tggtcaggta gagaatacca aggcgcttga
      241 gagaactcgg gtgaaggaac taggcaaaat ggtgccgtaa cttcgggaga aggcacgctg
      301 atatgtaggt gaagtccctc gcggatggag ctgaaatcag tcgaagatac cagctggctg
      361 caactgttta ttaaaaacac agcactgtgc aaacacgaaa gtggacgtat acggtgtgac
      421 gcctgcccgg tgc
//
LOCUS       DAPOAV010000340          421 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.374, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000340 DAPOAV010000000
VERSION     DAPOAV010000340.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.374"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(107..>421)
                     /gene="tnpB"
                     /locus_tag="RN951_004770"
     CDS             complement(107..>421)
                     /gene="tnpB"
                     /locus_tag="RN951_004770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019104956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDX2529611.1"
                     /translation="LVAGITDMRNGFNGLAAKVQTTLKDDPMSGHVFIFRGRNGSQVK
                     LLWSTGDGLCLLTKRLERGRFAWPSARDGKVFLTPAQLAMLLEGIDWRQPKRLLTSLT
                     ML"
BASE COUNT           94 a          121 c          116 g           90 t
ORIGIN      
        1 cctgttcggc aaggagacgt ttcagtgcat tgatatcgtc aggaagtgag ctgctcatac
       61 cgggtatatt accaggctca ttcagcgtcg accaggataa agaggcttac aacatagtca
      121 gggacgtaag cagtctttta ggctgccgcc agtcgatacc ttccagcagc atcgccagct
      181 gtgccggtgt gaggaacact ttgccatccc gggctgacgg ccaggcgaag cggccgcgct
      241 ccagccgttt ggtcagcaga cacagtccat cgccggtaga ccagaggagc tttacctgac
      301 tgccattacg cccacggaag ataaaaacgt gacctgacat cggatcgtct ttcagcgtcg
      361 tctgcacctt tgccgccagg ccgttgaagc cgtttctcat atcggtgatg ccagcgacca
      421 g
//
LOCUS       DAPOAV010000341          394 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.376, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000341 DAPOAV010000000
VERSION     DAPOAV010000341.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..394
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.376"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
BASE COUNT           72 a          135 c          111 g           76 t
ORIGIN      
        1 ccttttccgg gcgtccccct ggcggggcgg gctgtcgtga acggagccag cgaagctgtc
       61 tccgccctgg cgggcttcca tccctgacgc aaaaacccgg gtttgcagcg accggaacgg
      121 tcgcgccacc cttgtcgcgc cgtggcctgc gctcccggca tcccggcaaa agacgccggg
      181 atgtaaggag caacgccgtt tcgcaaaccg cgcttcacgt cgttgcggcg ggtccctgcc
      241 cgttgttctg tccggtgcca ttcacctgtt taagcccctg tcgccggggg catagacagc
      301 cacaacctgc cgcactgact gtccagggta aatgaacagc ccacaaaatt ttttacccaa
      361 aacccggtaa aaaattttgc gttctgccca ggac
//
LOCUS       DAPOAV010000342          391 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.denovo.377, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000342 DAPOAV010000000
VERSION     DAPOAV010000342.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.denovo.377"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            complement(<1..353)
                     /locus_tag="RN951_004771"
     CDS             complement(<1..353)
                     /locus_tag="RN951_004771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDX2529612.1"
                     /translation="MYWIINDNIEFWPEHRKLISVHNADLNVVLTTPASRCLSLLLEA
                     FPDVVAQQDFFTRVWEEEGMRVPTNTLYQNISIIRRGFRAVGDTTHSLIATVPRRGFK
                     IHNDINIQNHVINSST"
BASE COUNT          116 a           77 c           83 g          115 t
ORIGIN      
        1 gttgacgagt ttattacatg attttgtatg ttaatgtcat tatggatctt gaatcctctt
       61 ctcggcacgg ttgcaattag cgagtgggta gtatcaccaa cagcgcgaaa tccgcgtctg
      121 ataatggata tgttctgata taacgtgtta gtaggcacac gcataccttc ttcttcccag
      181 actctggtga aaaaatcttg ttgtgcaacc acatcaggaa aagcttcaag tagaagtgat
      241 aaacatcgac tggctggcgt tgtcagaacg acgttaagat cggcgttatg taccgatatt
      301 aattttcggt gctcaggcca gaactcgata ttatcgttaa taatccagta catacgtcaa
      361 taaacactaa atcaatcgaa atggagatca c
//
LOCUS       DAPOAV010000343         8818 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.guided.132, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000343 DAPOAV010000000
VERSION     DAPOAV010000343.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8818
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.guided.132"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            133..339
                     /locus_tag="RN951_004772"
                     /pseudo
     CDS             133..339
                     /locus_tag="RN951_004772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706235.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RtcB family protein"
     gene            335..856
                     /locus_tag="RN951_004773"
                     /pseudo
     CDS             335..856
                     /locus_tag="RN951_004773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602105.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor H"
     gene            complement(913..2370)
                     /gene="pepD"
                     /locus_tag="RN951_004774"
     CDS             complement(913..2370)
                     /gene="pepD"
                     /locus_tag="RN951_004774"
                     /EC_number="3.4.13.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosol nonspecific dipeptidase"
                     /protein_id="HDX2529613.1"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKG
                     FHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQGNWL
                     QADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGG
                     EIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDVL
                     KSLVNTYQEILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATPNGVIRN
                     SDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEA
                     KGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIG
                     PTITGPHSPDEQVHIESVGHYWTLLTELLKEIPAK"
     gene            2631..3089
                     /gene="gpt"
                     /locus_tag="RN951_004775"
     CDS             2631..3089
                     /gene="gpt"
                     /locus_tag="RN951_004775"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDX2529614.1"
                     /translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR"
     gene            3181..4425
                     /gene="frsA"
                     /locus_tag="RN951_004776"
     CDS             3181..4425
                     /gene="frsA"
                     /locus_tag="RN951_004776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase FrsA"
                     /protein_id="HDX2529615.1"
                     /translation="MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTI
                     PHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     TQAMVWQQKACAEDDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
                     AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYF
                     APRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFN
                     PVYRNFDKGLQEITDWIEKRLC"
     gene            4483..4884
                     /gene="crl"
                     /locus_tag="RN951_004777"
     CDS             4483..4884
                     /gene="crl"
                     /locus_tag="RN951_004777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-binding protein Crl"
                     /protein_id="HDX2529616.1"
                     /translation="MTLPSGHPKSRLIKKFTALGPYIREGKCEDNRFFFDCLAVCVNV
                     KPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWKSVPVKDTEVVERLEHTLRE
                     FHEKLRELLTTLNLKLEPADDFRDEPVKLTA"
     gene            complement(4923..5978)
                     /gene="phoE"
                     /locus_tag="RN951_004778"
     CDS             complement(4923..5978)
                     /gene="phoE"
                     /locus_tag="RN951_004778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoporin PhoE"
                     /protein_id="HDX2529617.1"
                     /translation="MKKSTLALVVMGIVASASVQAAEIYNKDGNKLDVYGKVKAMHYM
                     SDNASKDGDQSYIRFGFKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGL
                     KYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFF
                     GVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFSISGAYTNSDRTNEQN
                     LQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPITGGFANKTQNFEAVAQYQF
                     DFGLRPSLGYVLSKGKDIEGIGDEDLVNYIDVGATYYFNKNMSAFVDYKINQLDSDNK
                     LNINNDDIVAVGMTYQF"
     gene            6266..7369
                     /gene="proB"
                     /locus_tag="RN951_004779"
     CDS             6266..7369
                     /gene="proB"
                     /locus_tag="RN951_004779"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HDX2529618.1"
                     /translation="MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHR
                     IVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQML
                     LTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILA
                     GADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKL
                     QAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAG
                     EITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDA
                     LRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR"
     gene            7381..8634
                     /gene="proA"
                     /locus_tag="RN951_004780"
     CDS             7381..8634
                     /gene="proA"
                     /locus_tag="RN951_004780"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HDX2529619.1"
                     /translation="MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILN
                     ANAQDVADARANGLSEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSG
                     LRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQ
                     DALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVI
                     TGGIGVCHIYVDESVEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQ
                     MAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIR
                     EHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLH
                     ARGPMGLEALTTYKWIGIGDYTIRA"
BASE COUNT         2147 a         2196 c         2315 g         2160 t
ORIGIN      
        1 aaataattcg agttgcagga aggcgacaag cgagtgaatc gccaggagct tacataagta
       61 agtgactggg gtgaacgaac gcagtcgcag tacatgcaac ttgaagtatg acgagtataa
      121 atggaatggt acatgggcaa atatattcgt cccttatccg atgcggtatt taccatcgca
      181 tctgatgacc tgtggatcga gagtttagcg atccaacaat tacacaccac ggcaaattta
      241 cccaacatgc agcgcgtagt ggggatgcca gatttacacc ccggacgcgg ctacccgatt
      301 ggcgcagcgt tcttctctgt tggtcgtttt tacccggcaa gacgtcgcgg taacggtgct
      361 ggaaacagaa acgggccgct actctgacac actgcgttcg gcgctggttt ctctcgatgg
      421 cgataacgca tgggcattaa gcgaaagctg gtgtggcact attcagtgga tttgtccgag
      481 tccgtatcgg cctcatcatg ggcgcaaaaa ctggtttctg ggcattgggc gttttaccgc
      541 tgatgagcag gaacaatcgg atgcaatccg ttatgagacg ctgcgttcgt cggggccggg
      601 cggtcaacat gtcaataaaa ccgactcggc ggtacgcgcc acgcatttgg catccggtat
      661 tagcgtgaag gttcagtcag agcgtagtca gcatgctaac aagcggctgg cacgattgct
      721 gattgcctgg aagctggagc aacagcaaca ggaaaatagc gcggcgctga aatcgcagcg
      781 gcgaatgttc catcaccaga ttgaacgtgg caacccgcga cggacattta cagggatggc
      841 ttttatcgaa ggataatgaa ggatgaaact gccggaaggc gattaaacgc catccggcag
      901 caaatcaaat aattacttcg ccggaatttc tttcagcagt tcagtcagca gtgtccagta
      961 atgacctacg ctttcgatgt gaacttgctc atccggagag tgtggaccgg tgatagttgg
     1021 cccgatagaa accatgtcca tttccggata cggttttttg aacagaccac attccaggcc
     1081 cgcgtggata atctggatgt tcggcgtctt gttgaacagg cgctgatagg tttcacgtac
     1141 cagatgcatc accggagaat tagcgtccgg ctgccagcca ggatatgcgc ctttcgcttc
     1201 ggttttcgcg ccagccagtt tacccagcga atccagcatg ctcaccacgt agtctttacc
     1261 gctgtcgatc agtgaacgga tcaggcagtg aatttctacg ttattgtcag tcatggtcac
     1321 cacaccgacg ttcagggagg tttcaaccac acctttggct acatcggagt tacgaatcac
     1381 accgttcggg gtggcgttca gcagacgaat aaaggtatcg cgagatttcg caatcagggc
     1441 agctttatcg ttcgctacag agtccagcaa caaggccaga tttttctctt tttctgccag
     1501 ctcgtttttc aggatctcct gataggtatt caccagagat ttcaggacgt cgactttatc
     1561 agctgcgaca gcaatggtcg caaaggcttc acgcgggatg gcgttacgca gtgtgccgcc
     1621 gttgaaatcg ataaggcgca gatccagttc ttccgcatga cccgccagga agcgcaccag
     1681 cagtttgttg gcattaccca gcccaacgtg gatttccccg ccggagtgac cgcctttcag
     1741 accttttaag gttaacttga aggtttcaaa accagctgga accgcttcac gatctaaatg
     1801 caggttggag gtgaagtcga taccccccgc acaacccatg tagatttcac cttcttcttc
     1861 ggagtcggtg ttaatcagaa tatcagcctg caaccagttg ccctgtaagc cgaacgcacc
     1921 gtccataccg gcttcttcgg tcatggtcag cagcacttcc agcgggccgt gaaccacgtt
     1981 ttcgtcagcc agaaccgcca gcgcagaggc cataccaatg ccgttatccg cacccagcgt
     2041 ggtgccgcgc gctttaaccc attcgccatc aatataaggc tggataggat ctttcgtgaa
     2101 gtcatgcacg gtgtcgttat ttttctgcgg caccatatcg aggtgggcct gtaagacgac
     2161 cggtttacga ttttccatac ctgcggtagc aggtttacga atcaggatat tacctacctg
     2221 atcgcgttcg acatggaaac ctttctcttt tgcccaacca acaatgtatt cagcgagttg
     2281 ctcttcatga taggacgggt gaggaataga acagattttg gcaaaaatat cccacagcgg
     2341 ctgtggagat aattgagaca gttcagacac gttaagtctc cttgtcgatc acccgcaaaa
     2401 cagtattgca ggtcacaggg ttagcagaaa atgttgtcaa cacaagacag gcttgcgaga
     2461 tatgtttgag aataccactt tatcccgcgt cagggagagg cagtgcgtaa aaagacgcgg
     2521 actcatgtga aatactggtt tttagtgcgc cagatctcta taatctcgcg caacctattt
     2581 tcccctcgaa cactttttaa gccgtagata aacaggctgg gacacttcac atgagcgaaa
     2641 aatacatcgt cacctgggac atgttgcaga tccatgcacg taaactcgca agccgactga
     2701 tgccttctga acaatggaaa ggcattattg ccgtaagccg tggcggtctg gtaccgggtg
     2761 cgttactggc gcgtgaactg ggtattcgtc atgtcgatac cgtttgtatt tccagctacg
     2821 atcacgacaa ccagcgcgag cttaaagtgc tgaaacgcgc agaaggcgat ggcgaaggct
     2881 tcatcgttat tgatgacctg gtggataccg gtggtactgc ggttgcgatt cgtgaaatgt
     2941 atccaaaagc gcactttgtc accatcttcg caaaaccggc tggtcgtccg ctggttgatg
     3001 actatgttgt tgatatcccg caagatacct ggattgaaca gccgtgggat atgggcgtcg
     3061 tattcgtccc gccaatctcc ggtcgctaat cttttcaacg cctggcactg ccgggcgttg
     3121 ttctttttaa cttcaggcgg gttacaatag tttccagtaa gtattctgga ggctgcatcc
     3181 atgacacagg caaacctgag cgaaaccctg ttcaaacccc gctttaaaca tcctgaaacc
     3241 tcgacgctag tccgccgctt taatcacggc gcacaaccgc ctgtgcagtc ggcccttgat
     3301 ggtaaaacca tccctcactg gtatcgcatg attaaccgtc tgatgtggat ctggcgcggc
     3361 attgacccac gcgaaatcct cgacgtccag gcacgtattg tgatgagcga tgccgaacgt
     3421 accgacgatg atttatacga tacggtgatt ggctaccgtg gcggcaactg gatttatgag
     3481 tgggccaccc aggcgatggt gtggcaacaa aaagcctgtg cggaagacga tccgcaactc
     3541 agtggtcgtc actggctgca tgcggctacg ttgtacaaca ttgccgccta tcctcatctg
     3601 aaaggagatg acctggccga gcaagcgcag gctttgtcaa accgcgccta tgaagaggcc
     3661 gctcagcgtc taccgggcac gatgcggcag atggagttta ccgtacccgg cggtgcgccc
     3721 atcaccggct ttttgcatat gccgaaaggc gatggcccgt tcccgacggt attaatgtgt
     3781 ggtggtctgg atgcgatgca gacggactat tacagcctgt atgaacgtta ttttgcgccg
     3841 cgcggcattg cgatgctgac tattgatatg ccgtcggtgg gcttttcttc aaaatggaag
     3901 ctcacccagg actccagcct gttgcatcag cacgtcttaa aggcgctgcc taacgtaccg
     3961 tgggtggatc acactcgcgt cgcggccttt ggtttccgtt tcggcgctaa cgttgccgtg
     4021 cgtctggcat accttgaatc gccgcgtctg aaagcggttg cctgtcttgg tccggtagtt
     4081 cataccctgt tgagtgattt taagtgccag caacaggtgc cggaaatgta tcttgacgtt
     4141 ctggccagtc gtttggggat gcatgatgct tccgatgaag cgttgcgcgt ggagctgaat
     4201 cgctattcat taaaagtgca aggattgctg ggacgtcgct gcccaacgcc aatgttatca
     4261 ggctactgga agaacgatcc gttcagcccg gaagaggact cacgcttaat cacctcatca
     4321 tctgctgacg gtaaattatt agagatccca tttaacccgg tgtatcggaa ttttgacaaa
     4381 ggtcttcagg aaatcaccga ctggatcgaa aaacgcttgt gttaaaaatt tgctaaattt
     4441 tgccaatttg gtaaaacagt tgcatcacaa caggagatag caatgacgtt accgagtgga
     4501 cacccgaaga gcagattgat caaaaaattt accgcactag gcccgtatat tcgtgaaggt
     4561 aagtgcgaag ataatcgatt ctttttcgat tgtctggctg tatgcgtcaa cgtgaaaccg
     4621 gcaccggaag tgcgtgaatt ctggggctgg tggatggagc tggaagcgca ggaatcccgt
     4681 tttacctaca gttaccagtt tggtctgttc gataaagcag gcgactggaa gagtgttccg
     4741 gtaaaagaca ctgaagtggt tgaacgactg gagcacaccc tgcgtgagtt tcacgagaag
     4801 ctgcgtgaac tgctgacgac gctgaatctg aagctggaac cggcggatga ttttcgtgac
     4861 gagccggtga agttaacggc gtgagtgaaa tgtgccggat gcatcacatc cggcaatatt
     4921 cattaaaact gatacgtcat gccaaccgcg acaatatcat cattattaat attcaatttg
     4981 ttatcgctat ccagttggtt gattttataa tcaacaaacg ctgacatatt tttgttgaaa
     5041 taatacgtag caccgacgtc gatataattg accagatctt catcaccgat accttcaata
     5101 tctttccctt tcgataagac ataacccagc gatggacgca gaccaaagtc aaactggtat
     5161 tgagcgaccg cttcaaagtt ctgtgtctta ttggcaaagc cgccagttat tggcgtcatt
     5221 ttgcgtgttt cagaatagaa agttgccaga taaatattat tggcatcgta tttcagacct
     5281 gttgcccatg cttctgcacg cttgcctgtg ccacggcttt gcaggttctg ctcgttggtg
     5341 cgatctgagt tggtataggc cccactaatg gagaaatcgc tgccgccaaa gtcatatgtc
     5401 aatgacgtgc cgaagccatc gccgttttgc tttttaacgt cgcggttttc gtttttccct
     5461 tgatattgca gggttaagtt caggccatcg ataacgccga agaagtcggt gttccgatac
     5521 gtcgccagac cgctggcgcg tttggtcata aagttgtcgg tctgcgccga ggaatcgcca
     5581 ccaaattccg ggaacatatc ggtccaggct tccacgtcat acaacgcccc caggttacga
     5641 ccataatcga aagaacccaa atctttatat ttcaacccgg caaaagcgag acgcgttttt
     5701 tgctgtgcag tatcactctc tgctttatta ccggcaaact ctgcttccca acgaccataa
     5761 ccagtcagtt gatcgttaat ttgtgtttcg cctttaaaac caaaacggat ataactctgg
     5821 tcgccatctt tactggcgtt atcactcata taatgcatgg ctttaacttt gccatagaca
     5881 tccagtttat taccgtcttt attatatatt tctgcagcct gtacagatgc agatgccaca
     5941 atgcccatca ccactaatgc cagagtgctc tttttcattt tcattcctga ttttaattaa
     6001 cgcgcgaata ttcagcggga gagtcccgtt gaaaacagga aagtttttaa cctgagattg
     6061 ttaaagatat attacagatt aataatattc ttaaaatgtg gtaatttatt aaatctgtaa
     6121 taaaagcgta aacaactgcc gctaggcttg ctgatcccgc gcaacaaaac gccatgcttt
     6181 gctcgcagat ggttggcaac cgacgacagt cctgctaaaa cgttcgtttg atatcatttt
     6241 tcctaaaatt gaatggcaga gaatcatgag tgacagccag acgctggtgg taaaactcgg
     6301 caccagtgtg ctaacaggcg gatcgcgccg tctgaaccgt gcccatatcg ttgaacttgt
     6361 tcgccagtgc gcgcagttac atgccgccgg gcatcggatt gttattgtga cgtcgggcgc
     6421 gatcgccgcc ggacgtgagc acctgggtta cccggaactg ccagcgacca tcgcctcgaa
     6481 acaactgctg gcggcggtag ggcagagtcg actgattcaa ctgtgggaac agctgttttc
     6541 gatttatggc attcacgtcg ggcaaatgct gctgacccgt gctgatatgg aagaccgtga
     6601 acgcttcctg aacgcccgcg acaccctgcg agcgttgctc gataacaata tcgttccggt
     6661 aatcaatgag aacgatgctg tcgctacggc agagattaag gtcggcgata acgataacct
     6721 ttctgcgctg gcggcgattc ttgcgggtgc cgataaactg ttgctgctga ccgatcaaaa
     6781 aggtttgtat accgctgacc cgcgcagcaa tccgcaggca gaactgatta aagatgttta
     6841 cggcattgat gacgcactgc gcgcgattgc cggtgacagc gtttcaggcc tcggaactgg
     6901 cggcatgagt accaaattgc aggccgctga cgtggcttgc cgtgcgggta tcgacaccat
     6961 tattgccgcg ggcagcaagc cgggcgttat tggtgatgtg atggaaggca tttccgtcgg
     7021 tacgctgttc catgcccagg cgactccgct tgaaaaccgt aaacgctgga ttttcggtgc
     7081 gccgccggcg ggtgaaatca cggtagatga aggggcaact gccgccattc tggaacgcgg
     7141 cagctccctg ttgccgaaag gcattaaaag cgtgactggc aatttctcgc gtggtgaagt
     7201 catccgcatt tgcaacctcg aaggccgcga tatcgcccac ggcgtcagtc gttacaacag
     7261 cgatgcatta cgccgtattg ccggacacca ctcgcaagaa attgatgcaa tactgggata
     7321 tgaatacggc ccggttgccg ttcaccgtga tgacatgatt acccgttaag gagcaggctg
     7381 atgctggaac aaatgggcat tgccgcgaag caagcctcgt ataaattagc gcaactctcc
     7441 agccgcgaaa aaaatcgcgt gctggaaaaa atcgccgatg aactggaagc acaaagcgaa
     7501 atcatcctca acgctaacgc ccaggatgtt gctgacgcgc gagccaatgg ccttagcgaa
     7561 gcgatgcttg accgtctggc actgacgccc gcacggctga aaggcattgc cgacgatgta
     7621 cgtcaggtgt gcaacctcgc cgatccggtg gggcaggtaa tcgatggcgg cgtactggac
     7681 agcggcctgc gtcttgagcg tcgtcgcgta ccgctggggg ttattggcgt gatttatgaa
     7741 gcgcgcccga acgtgacggt tgatgtcgct tcgctgtgcc tgaaaaccgg taatgcggtg
     7801 atcctgcgcg gtggcaaaga aacgtgtcgc actaacgctg caacggtggc ggtgattcag
     7861 gacgccctga aatcctgcgg cttaccggcg ggtgccgtgc aggcgattga taatcctgac
     7921 cgtgcgctgg tcagtgaaat gctgcgtatg gataaataca tcgacatgct gatcccgcgt
     7981 ggtggcgctg gtttgcataa actgtgccgt gaacagtcga caatcccggt gatcacaggt
     8041 ggtataggcg tatgccatat ttacgttgat gaaagtgtag agatcgctga agcattaaaa
     8101 gtgatcgtca acgcgaaaac tcagcgtccg agcacatgta atacggttga aacgttgctg
     8161 gtgaataaaa acatcgccga tagcttcctg cccgcattaa gcaaacaaat ggcggaaagc
     8221 ggcgtgacat tacacgcaga tgcagctgca ctggcgcagt tgcaggcagg ccctgcgaag
     8281 gtggttgctg ttaaagccga agagtatgac gatgagtttc tgtcattaga tttgaacgtc
     8341 aaaatcgtca gcgatcttga cgatgccatc gcccatattc gtgaacacgg cacacaacac
     8401 tccgatgcga tcctgacccg cgatatgcgc aacgcccagc gttttgttaa cgaagtggat
     8461 tcgtccgctg tttacgttaa cgcctctacg cgttttaccg acggcggcca gtttggtctg
     8521 ggtgcggaag tggcggtaag cacacaaaaa ctccacgcgc gtggcccaat ggggctggaa
     8581 gcactgacca cttacaagtg gatcggcatt ggtgattaca ccattcgtgc gtaaataaaa
     8641 ccgggtgatg caaaagtagc catttgattc acaaggccat tgacgcatcg cccggttagt
     8701 tttaaccttg cccaccgtga ttcacgttcg tgaacatgtc ctttcagggc cgatatagct
     8761 cagttggtag agcagcgcat tcgtaatgcg aaggtcgtag gttcgactcc tattatcg
//
LOCUS       DAPOAV010000344         4813 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.guided.182, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000344 DAPOAV010000000
VERSION     DAPOAV010000344.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4813
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.guided.182"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..1006
                     /locus_tag="RN951_004781"
     CDS             <1..1006
                     /locus_tag="RN951_004781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031587700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS1380-like element ISEc9 family transposase"
                     /protein_id="HDX2529620.1"
                     /translation="KGCLIANFATVPFNFKTTQMFRDINFKVFKKLLTKSKLTSITID
                     IDSSVINVEGHQEGASKGYNPKKLGNRCYNIQFAFCDELKAYVTGFVRSGNTYTANGA
                     AEMIKEIVANIKSDDLEILFRMDSGYFDEKIIETIESLGCKYLIKAKSYSTLTSQATN
                     SSIVFVKGEEGRETTELYTKLVKWEKDRRFVVSRVLKPEKERAQLSLLEGSEYDYFFF
                     VTNTTLLSEKVVIYYEKRGNAENYIKEAKYDMAVGHLLLKSFWANEAVFQMMMLSYNL
                     FLLFKFDSLDSSEYRQQIKTFRLKYVFLAAKIIKTARYVIMKLSENYPYKGVYEKCLV
                     "
     gene            1262..2137
                     /locus_tag="RN951_004782"
     CDS             1262..2137
                     /locus_tag="RN951_004782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011091028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A extended-spectrum beta-lactamase
                     CTX-M-15"
                     /protein_id="HDX2529621.1"
                     /translation="MVKKSLRQFTLMATATVTLLLGSVPLYAQTADVQQKLAELERQS
                     GGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKK
                     SDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPASVTAFARQLGD
                     ETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRAQLVTWMKGNT
                     TGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQPQPKAESR
                     RDVLASAAKIVTDGL"
     gene            complement(2184..2516)
                     /locus_tag="RN951_004783"
     CDS             complement(2184..2516)
                     /locus_tag="RN951_004783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001393253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WbuC family cupin fold metalloprotein"
                     /protein_id="HDX2529622.1"
                     /translation="MRPHRHPHTFELLLPLRGRFVVLNFDDRGTVTHRAILGETCTVL
                     EMAAGTWHAVLSLDTGGIIFEVKHGGYQPVAADDYAHWAPAEGEPGTTELMAWYAQAQ
                     VGDSTFAV"
     gene            2530..4773
                     /locus_tag="RN951_004784"
                     /pseudo
     CDS             2530..4773
                     /locus_tag="RN951_004784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
BASE COUNT         1312 a         1104 c         1211 g         1186 t
ORIGIN      
        1 aaaaggctgc ctcatcgcta actttgcaac agtgcccttc aacttcaaga caacccaaat
       61 gtttagagac attaatttta aagtctttaa aaaactgctc actaaaagta aattgacatc
      121 cattacgatt gatattgata gtagtgtaat taacgtagaa ggtcatcaag aaggtgcgtc
      181 aaaaggatat aatcctaaga aactgggaaa ccgatgctac aatatccaat ttgcattttg
      241 cgacgaatta aaagcatatg ttaccggatt tgtaagaagt ggcaatactt acactgcaaa
      301 cggtgctgcg gaaatgatca aagaaattgt tgctaacatc aaatcagacg atttagaaat
      361 tttatttcga atggatagtg gctactttga tgaaaaaatt atcgaaacga tagaatctct
      421 tggatgcaaa tatttaatta aagccaaaag ttattctaca ctcacctcac aagcaacgaa
      481 ttcatcaatt gtattcgtta aaggagaaga aggtagagaa actacagaac tgtatacaaa
      541 attagttaaa tgggaaaaag acagaagatt tgtcgtatct cgcgtactga aaccagaaaa
      601 agaaagagca caattatcac ttttagaagg ttccgaatac gactactttt tctttgtaac
      661 aaatactacc ttgctttctg aaaaagtagt tatatactat gaaaagcgtg gtaatgctga
      721 aaactatatc aaagaagcca aatacgacat ggcggtgggt catctcttgc taaagtcatt
      781 ttgggcgaat gaagccgtgt ttcaaatgat gatgctttca tataacctat ttttgttgtt
      841 caagtttgat tccttggact cttcagaata cagacagcaa ataaagacct ttcgtttgaa
      901 gtatgtattt cttgcagcaa aaataatcaa aaccgcaaga tatgtaatca tgaagttgtc
      961 ggaaaactat ccgtacaagg gagtgtatga aaaatgtctg gtataataag aatatcatca
     1021 ataaaattga gtgttgctct gtggataact tgcagagttt attaagtatc attgcagcaa
     1081 agatgaaatc aatgatttat caaaaatgat tgaaaggtgg ttgtaaataa tgttacaatg
     1141 tgtgagaagc agtctaaatt cttcgtgaaa tagtgatttt tgaagctaat aaaaaacaca
     1201 cgtggaattt agggactatt catgttgttg ttatttcgta tcttccagaa taaggaatcc
     1261 catggttaaa aaatcactgc gccagttcac gctgatggcg acggcaaccg tcacgctgtt
     1321 gttaggaagt gtgccgctgt atgcgcaaac ggcggacgta cagcaaaaac ttgccgaatt
     1381 agagcggcag tcgggaggca gactgggtgt ggcattgatt aacacagcag ataattcgca
     1441 aatactttat cgtgctgatg agcgctttgc gatgtgcagc accagtaaag tgatggccgc
     1501 ggccgcggtg ctgaagaaaa gtgaaagcga accgaatctg ttaaatcagc gagttgagat
     1561 caaaaaatct gaccttgtta actataatcc gattgcggaa aagcacgtca atgggacgat
     1621 gtcactggct gagcttagcg cggccgcgct acagtacagc gataacgtgg cgatgaataa
     1681 gctgattgct cacgttggcg gcccggctag cgtcaccgcg ttcgcccgac agctgggaga
     1741 cgaaacgttc cgtctcgacc gtaccgagcc gacgttaaac accgccattc cgggcgatcc
     1801 gcgtgatacc acttcacctc gggcaatggc gcaaactctg cggaatctga cgctgggtaa
     1861 agcattgggc gacagccaac gggcgcagct ggtgacatgg atgaaaggca ataccaccgg
     1921 tgcagcgagc attcaggctg gactgcctgc ttcctgggtt gtgggggata aaaccggcag
     1981 cggtggctat ggcaccacca acgatatcgc ggtgatctgg ccaaaagatc gtgcgccgct
     2041 gattctggtc acttacttca cccagcctca acctaaggca gaaagccgtc gcgatgtatt
     2101 agcgtcggcg gctaaaatcg tcaccgacgg tttgtaatag cggaaacgga atggggaaac
     2161 tcattccgtt tttgtttatc gccttagacg gcaaaagtgc tgtcgcccac ctgcgcttgc
     2221 gcataccagg ccataagctc cgtggttcct ggttctcctt ccgctggagc ccagtgcgca
     2281 tagtcatcgg cagccacggg ttgatagcca ccgtgtttta cttcaaaaat tatgccaccg
     2341 gtatccagcg acagcacggc atgccaggtt cctgcggcca tctccagcac cgtacaggtt
     2401 tcccccaata tcgcccgatg ggtgacggta ccccgatcgt caaaattcag caccacgaaa
     2461 cgacccctta atggcaacag tagctcgaag gtgtgagggt gtcggtgcgg gcgcacgtag
     2521 gtcccaggtc atattccttc cggcgtccgg cattttaccg ccagacagct cgggattcgt
     2581 gatatcaccg ttcttgcaga atacggtcag agggaaaata cccgccgtga gcatgcagcg
     2641 ctgatacgtc agcactatca gtatcgtgaa tttgcctggc cctggacatt tcgccttacc
     2701 cgtcttttat atacccggag ctggataagc aacgaacgtc ctggcctgct tttcgatctg
     2761 gcgacagggt ggcttatgca acatcgtatt attctccccg gagccactac gctgatccgg
     2821 ttgatttcag aggtaaggga aaaggcgacg ttgcgcctgt ggaacaaact ggcactgata
     2881 ccgtcagccg aacagcgttc acagctggag atgctgctgg ggccaactga ttgcagccgc
     2941 ctgtctttac tggaatcact gaaaaagggc cctgtgacca tcagtggtcc ggcgtttaat
     3001 gaagcaattg aacgctggaa aactctgaac gattttggcc tgcatgctga aaacctgagt
     3061 acactcccgg ctgtgcgcct gaaaaatctc gcacgttatg ctggtatgac ttcggtgttc
     3121 aatattgcca ggatgtcacc gcagaaaagg atggcggttc tggttgcctt tgtccttgca
     3181 tgggaaacgc tggcgctgga tgatgcattg gacgttctgg acgccatgct ggccgttatc
     3241 atccgtgacg ccagaaagat tgggcagaaa aaacggctcc gctcgctgaa ggatctggat
     3301 aaatctgcat tggcgctcgc cagcgcatgt tcgtacctgc tgaaagaaga aacaccggac
     3361 gaatcgattc gtgctgaggt gttcagctac atcccaaggc aaaagctggc tgaaatcatc
     3421 acgcttgtcc gtgaaattgc ccggccctca gacgataatt ttcatgaaga aatggtggag
     3481 cagtacgggc gcgttcgtcg tttcctgccc catctgctga ataccgttaa attttcatcc
     3541 gcacctgccg gggttaccac tctgaatgcc tgtgactacc tcagccggga gttcagctca
     3601 cggcggcagt tttttgacga cgcaccaacg gaaattatca gtcggtcatg gaaacggctg
     3661 gtgattaaca aggaaaaaca tatcacccgc aggggataca cgctctgctt tctcagtaaa
     3721 ctgcaggata gtctgaggcg gagggatgtc tacgttaccg gcagtaaccg gtggggagat
     3781 cctcgtgcaa gattactaca gggtgctgac tggcaggcaa accggattaa ggtttatcgt
     3841 tctttggggc acccgacaga cccgcaggaa gcaataaaat ctctgggtca tcagcttgat
     3901 agtcgttaca gacaggttgc tgcacgtctt tgcgaaaatg aggctgtcga actcgatgtt
     3961 tctggcccga agccccggtt gacaatttct cccctcgcca gtcttgatga gccggacagt
     4021 ctgaaacgac tgagcaaaat gatcagtgat ctactccctc cggtggattt aacggagttg
     4081 ctgctcgaaa ttaacgccca taccggattt gctgatgagt ttttccatgc tagtgaagcc
     4141 agtgccagag ttgatgatct gcccgtcagc atcagcgccg tgctgatggc tgaagcctgc
     4201 aatatcggtc tggaaccact gatcagatca aatgttcctg cactgacccg acaccggctg
     4261 aactggacaa aagcgaacta tctgcgggct gaaactatca ccagcgctaa tgccagactg
     4321 gttgattttc aggcaacgct gccactggca cagatatggg gtggaggaga agtggcatct
     4381 gcagatggaa tgcgctttgt tacgccagtc agaacaatca atgccggacc gaaccgcaaa
     4441 tactttggta ataacagagg gatcacctgg tacaactttg tgtccgatca gtattccggc
     4501 tttcatggca tcgttatacc ggggacgctg agggactcta tctttgtgct ggaaggtctt
     4561 ctggaacagg agaccgggct gaatccaacc gaaattatga ccgatacagc aggtgccagc
     4621 gaacttgtct ttggcctttt ctggctgctg ggataccagt tttctccacg cctggctgat
     4681 gccggtgctt cggttttctg gcgaatggac catgatgccg actatggcgt gctgaatgat
     4741 attgccagag ggcaatcaga tccccgaaaa atagggcact gttgcaaata gtcggtggtg
     4801 ataaacttat cat
//
LOCUS       DAPOAV010000345         4669 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.guided.186, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000345 DAPOAV010000000
VERSION     DAPOAV010000345.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4669
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.guided.186"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            41..361
                     /locus_tag="RN951_004785"
                     /pseudo
     CDS             41..361
                     /locus_tag="RN951_004785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
     gene            complement(339..962)
                     /gene="tetR(B)"
                     /locus_tag="RN951_004786"
     CDS             complement(339..962)
                     /gene="tetR(B)"
                     /locus_tag="RN951_004786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional
                     repressor TetR(B)"
                     /protein_id="HDX2529623.1"
                     /translation="MSRLDKSKVINSALELLNEVGIEGLTTRKLAQKLGVEQPTLYWH
                     VKNKRALLDALAIEMLDRHHTHFCPLEGESWQDFLRNNAKSFRCALLSHRDGAKVHLG
                     TRPTEKQYETLENQLAFLCQQGFSLENALYALSAVGHFTLGCVLEDQEHQVAKEERET
                     PTTDSMPPLLRQAIELFDHQGAEPAFLFGLELIICGLEKQLKCESGS"
     gene            1044..2249
                     /gene="tet(B)"
                     /locus_tag="RN951_004787"
     CDS             1044..2249
                     /gene="tet(B)"
                     /locus_tag="RN951_004787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001089064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(B)"
                     /protein_id="HDX2529624.1"
                     /translation="MNSSTKIALVITLLDAMGIGLIMPVLPTLLREFIASEDIANHFG
                     VLLALYALMQVIFAPWLGKMSDRFGRRPVLLLSLIGASLDYLLLAFSSALWMLYLGRL
                     LSGITGATGAVAASVIADTTSASQRVKWFGWLGASFGLGLIAGPIIGGFAGEISPHSP
                     FFIAALLNIVAFLVVMFWFRETKNTRDNTDTEVGVETQSNSVYITLFKTMPILLIIYF
                     SAQLIGQIPATVWVLFTENRFGWNSMMVGFSLAGLGLLHSVFQAFVAGRIATKWGEKT
                     AVLLGFIADSSAFAFLAFISEGWLVFPVLILLAGGGIALPALQGVMSIQTKSHQQGAL
                     QGLLVSLTNATGVIGPLLFAVIYNHSLPIWDGWIWIIGLAFYCIIILLSMTFMLTPQA
                     QGSKQETSA"
     gene            complement(2362..2955)
                     /gene="tetC"
                     /locus_tag="RN951_004788"
     CDS             complement(2362..2955)
                     /gene="tetC"
                     /locus_tag="RN951_004788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracyline resistance-associated
                     transcriptional repressor TetC"
                     /protein_id="HDX2529625.1"
                     /translation="MENKNHQQENFKSTYQSLVNSARILFVEKGYQAVSIDEISGKAL
                     VTKGAFYHHFKNKKQLLSACYKQQLIMIDAYITTKTDLTNGWSALESIFEHYLDYIID
                     NNKNLIPIQEVMPIIGWNELEKISLEYITGKVNAIVSKLIQENQLKAYDDDVLKNLLN
                     GWFMHIAIHAKNLKELADKKGQFIAIYRGFLLSLKDK"
     gene            3088..3459
                     /locus_tag="RN951_004789"
     CDS             3088..3459
                     /locus_tag="RN951_004789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004924490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDX2529626.1"
                     /translation="MQLRYDDKQFHTTVIKDVLLWIEHNLDQSLLLDDVANKAGYTKW
                     YFQRLFKKVTGVTLASYIRARRLTKAAVELRLTKKTILEIALKYQFDSQQSFTRRFKY
                     IFKVTPSYYRRNKLWELEAMH"
     gene            complement(3469..>4669)
                     /locus_tag="RN951_004790"
     CDS             complement(3469..>4669)
                     /locus_tag="RN951_004790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001339197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS4-like element ISVsa5 family transposase"
                     /protein_id="HDX2529627.1"
                     /translation="EHKTLSVSWSHYPELHLKRLNSLTLACHALLDCKTLTLTELGRN
                     LPTKARTKHNIKRIDRLLGNRHLHKERLAVYRWHASFICSGNTMPIVLVDWSDIREQK
                     RLMVLRASVALHGRSVTLYEKAFPLSEQCSKKAHDQFLADLASILPSNTTPLIVSDAG
                     FKVPWYKSVEKLGWYWLSRVRGKVQYADLGAENWKPISNLHDMSSSHSKTLGYKRLTK
                     SNPISCQILLYKSRSKGRKNQRSTRTHCHHPSPKIYSASAKEPWVLATNLPVEIRTPK
                     QLVNIYSKRMQIEETFRDLKSPAYGLGLRHSRTSSSERFDIMLLIALMLQLTCWLAGV
                     HAQKQGWDKHFQANTVRNRNVLSTVRLGMEVLRHSGYTITREDLLVAATLLAQNLFTH
                     GYALGKL"
BASE COUNT         1242 a          883 c         1000 g         1544 t
ORIGIN      
        1 aatatgatga tctcatatca ggaacttgtt cgcaccttcc ttagctggcg aagttgccgt
       61 taagatctat gattcccttt gtcaacagca atggatcact gaaaatggtt caatgatcac
      121 attaagtggt attcaatatt ttcatgaaat gggaattgac gttccttcca aacattcacg
      181 taaaatctgt tgtgcgtgtt tagattggag tgaacgccgt ttccatttag gtgggtacgt
      241 tggagccgca ttattttcgc tttatgaatc taaagggtgg ttaactcgac atcttggtta
      301 ccgtgaagtt accatcacgg aaaaaggtta tgctgctttt aagacccact ttcacattta
      361 agttgttttt ctaatccgca tatgatcaat tcaaggccga ataagaaggc tggctctgca
      421 ccttggtgat caaataattc gatagcttgt cgtaataatg gcggcatact atcagtagta
      481 ggtgtttccc tttcttcttt agcgacttga tgctcttgat cttccaatac gcaacctaaa
      541 gtaaaatgcc ccacagcgct gagtgcatat aatgcattct ctagtgaaaa accttgttgg
      601 cataaaaagg ctaattgatt ttcgagagtt tcatactgtt tttctgtagg ccgtgtacct
      661 aaatgtactt ttgctccatc gcgatgactt agtaaagcac atctaaaact tttagcgtta
      721 ttacgtaaaa aatcttgcca gctttcccct tctaaagggc aaaagtgagt atggtgccta
      781 tctaacatct caatggctaa ggcgtcgagc aaagcccgct tattttttac atgccaatac
      841 aatgtaggct gctctacacc tagcttctgg gcgagtttac gggttgttaa accttcgatt
      901 ccgacctcat taagcagctc taatgcgctg ttaatcactt tacttttatc taatctagac
      961 atcattaatt cctaattttt gttgacactc tatcattgat agagttattt taccactccc
     1021 tatcagtgat agagaaaagt gaaatgaata gttcgacaaa gatcgcattg gtaattacgt
     1081 tactcgatgc catggggatt ggccttatca tgccagtctt gccaacgtta ttacgtgaat
     1141 ttattgcttc ggaagatatc gctaaccact ttggcgtatt gcttgcactt tatgcgttaa
     1201 tgcaggttat ctttgctcct tggcttggaa aaatgtctga ccgatttggt cggcgcccag
     1261 tgctgttgtt gtcattaata ggcgcatcgc tggattactt attgctggct ttttcaagtg
     1321 cgctttggat gctgtattta ggccgtttgc tttcagggat cacaggagct actggggctg
     1381 tcgcggcatc ggtcattgcc gataccacct cagcttctca acgcgtgaag tggttcggtt
     1441 ggttaggggc aagttttggg cttggtttaa tagcggggcc tattattggt ggttttgcag
     1501 gagagatttc accgcatagt ccctttttta tcgctgcgtt gctaaatatt gtcgctttcc
     1561 ttgtggttat gttttggttc cgtgaaacca aaaatacacg tgataataca gataccgaag
     1621 taggggttga gacgcaatcg aattcggtat acatcacttt atttaaaacg atgcccattt
     1681 tgttgattat ttatttttca gcgcaattga taggccaaat tcccgcaacg gtgtgggtgc
     1741 tatttaccga aaatcgtttt ggatggaata gcatgatggt tggcttttca ttagcgggtc
     1801 ttggtctttt acactcagta ttccaagcct ttgtggcagg aagaatagcc actaaatggg
     1861 gcgaaaaaac ggcagtactg ctcggattta ttgcagatag tagtgcattt gcctttttag
     1921 cgtttatatc tgaaggttgg ttagttttcc ctgttttaat tttattggct ggtggtggga
     1981 tcgctttacc tgcattacag ggagtgatgt ctatccaaac aaagagtcat cagcaaggtg
     2041 ctttacaggg attattggtg agccttacca atgcaaccgg tgttattggc ccattactgt
     2101 ttgctgttat ttataatcat tcactaccaa tttgggatgg ctggatttgg attattggtt
     2161 tagcgtttta ctgtattatt atcctgctat cgatgacctt catgttaacc cctcaagctc
     2221 aggggagtaa acaggagaca agtgcttagt tatttcgtca ccaaatgatg ttattccgcg
     2281 aaatataatg accctcttga taacccaaga gggcattttt tacgataaag aagatttagc
     2341 ttcaaataaa acctatctat tttatttatc tttcaagctc aataaaaagc cgcggtaaat
     2401 agcaataaat tggccttttt tatcggcaag ctcttttagg tttttcgcat gtattgcgat
     2461 atgcataaac cagccattga gtaagttttt aagcacatca tcatcataag ctttaagttg
     2521 gttctcttgg atcaatttgc tgacaatggc gtttacctta ccagtaatgt attcaaggct
     2581 aattttttca agttcattcc aaccaatgat aggcatcact tcttggatag ggataaggtt
     2641 tttattatta tcaataatat aatcaagata atgttcaaat atactttcta aggcagacca
     2701 accatttgtt aaatcagttt ttgttgtgat gtaggcatca atcataatta attgctgctt
     2761 ataacaggca ctgagtaatt gttttttatt tttaaagtga tgataaaagg cacctttggt
     2821 caccaacgct tttcccgaga tctcatctat tgaaacagct tgatagcctt tttcaacaaa
     2881 caatattcgt gctgagttaa ccagtgattg ataggtactc ttaaaatttt cttgttgatg
     2941 atttttattt tccatgatag atttaaaata acataccgtc agtatgttta tggtatcatg
     3001 atgatgtggt cgtgacaatc ttaagaacat ttaggttatt ttatgtatat tgaacagcat
     3061 tctcgctatc aaaataaagc taataacatc caattaagat atgatgataa gcagtttcat
     3121 acaacggtta tcaaagatgt tctattatgg attgaacata atttagatca gtctttactg
     3181 cttgatgatg tggcgaataa agcgggttat accaagtggt attttcagcg gctgttcaaa
     3241 aaagtaacag gggtcacact ggctagctat attcgtgctc gtcgtttgac gaaagcggct
     3301 gttgagttga ggttgacgaa aaaaactatc cttgagatcg cattaaaata tcaatttgat
     3361 tcccaacaat cttttacacg tcgatttaag tacattttta aggttacacc aagttattat
     3421 cggcgtaata aattatggga attggaggca atgcactgag agatcccctc ataatttccc
     3481 caaagcgtaa ccatgtgtga ataaattttg agctagtagg gttgcagcca cgagtaagtc
     3541 ttcccttgtt attgtgtagc cagaatgccg caaaacttcc atgcctaagc gaactgttga
     3601 gagtacgttt cgatttctga ctgtgttagc ctggaagtgc ttgtcccaac cttgtttctg
     3661 agcatgaacg cccgcaagcc aacatgttag ttgaagcatc agggcgatta gcagcatgat
     3721 atcaaaacgc tctgagctgc tcgttcggct atggcgtagg cctagtccgt aggcaggact
     3781 tttcaagtct cggaaggttt cttcaatctg cattcgcttc gaatagatat taacaagttg
     3841 tttgggtgtt cgaatttcaa caggtaagtt agttgctaga acccatggct cctttgccga
     3901 cgctgagtag attttaggtg acgggtggtg acaatgagtc cgtgtcgagc gctgattttt
     3961 tcggccttta gagcgagatt tatacaatag aatttggcat gagattggat tgcttttagt
     4021 cagcctctta tagcctaaag tctttgagtg actagatgac atatcatgta agttgctgat
     4081 aggtttccag ttttccgctc ctaggtctgc atattgtact tttcctctta ctcgacttaa
     4141 ccagtaccaa cccagcttct caacggattt ataccatggc actttaaagc cagcatcact
     4201 gacaatgagc ggtgtggtgt tactcggtag aatgctcgca aggtcggcta gaaattggtc
     4261 atgagctttc tttgaacatt gctctgaaag cgggaacgct ttctcataaa gagtaacaga
     4321 acgaccgtgt agtgcgactg aagctcgcaa taccataagt cgtttttgct cacgaatatc
     4381 agaccagtca acaagtacaa tgggcatcgt attgcccgaa cagataaagc tagcatgcca
     4441 acggtataca gcgagtcgct ctttgtggag gtgacgatta cctaacaatc ggtcgattcg
     4501 tttgatgtta tgttttgttc tcgctttggt tggcaggtta cggccaagtt cggtaagagt
     4561 gagagtttta cagtcaagta atgcgtggca agccaacgtt aagctgttga gtcgttttaa
     4621 gtgtaattcg gggtaatgac tccaacttac tgatagtgtt ttatgttca
//
LOCUS       DAPOAV010000346         4502 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.guided.190, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000346 DAPOAV010000000
VERSION     DAPOAV010000346.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4502
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.guided.190"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            <1..1213
                     /locus_tag="RN951_004791"
     CDS             <1..1213
                     /locus_tag="RN951_004791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HDX2529628.1"
                     /translation="YRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGSGIL
                     MTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRK
                     GNTISTPRGDVVYLDLRHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTM
                     GGIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAAT
                     AGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQK
                     TIDKLAELQERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAH
                     QRLDEGCTERDDVNFLKHTLAFRDADGTTRLEYSDVKITTLPPAKRVYGGEADAADKA
                     EAANKKEKANG"
     gene            1206..1940
                     /gene="frdB"
                     /locus_tag="RN951_004792"
     CDS             1206..1940
                     /gene="frdB"
                     /locus_tag="RN951_004792"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase iron-sulfur protein"
                     /protein_id="HDX2529629.1"
                     /translation="MAEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYI
                     KDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERD
                     LVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACP
                     QFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKH
                     VDPAAAIQQGKVESSKDFLIATLKPR"
     gene            1951..2346
                     /gene="frdC"
                     /locus_tag="RN951_004793"
     CDS             1951..2346
                     /gene="frdC"
                     /locus_tag="RN951_004793"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdC"
                     /protein_id="HDX2529630.1"
                     /translation="MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELI
                     FGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDE
                     KMGPEPIIKSLWAVTVVATIVILFVALYW"
     gene            2357..2716
                     /gene="frdD"
                     /locus_tag="RN951_004794"
     CDS             2357..2716
                     /gene="frdD"
                     /locus_tag="RN951_004794"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdD"
                     /protein_id="HDX2529631.1"
                     /translation="MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGL
                     FPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFY
                     GLAAILTVVTLIGVVTI"
     gene            2779..3912
                     /locus_tag="RN951_004795"
     CDS             2779..3912
                     /locus_tag="RN951_004795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaEC family class C beta-lactamase"
                     /protein_id="HDX2529632.1"
                     /translation="MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGM
                     AVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLS
                     DPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAP
                     GTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWG
                     YREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYW
                     QTGDMYQGLGWEMLDWPVNPDSIINGSDNKIALAARPVKAITPPTPAVRASWVHKTGA
                     TGGFGSYVAFIPEKELGIVMLANKNYPNPARVDAAWQILNALQ"
     gene            4001..>4502
                     /gene="blc"
                     /locus_tag="RN951_004796"
     CDS             4001..>4502
                     /gene="blc"
                     /locus_tag="RN951_004796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin Blc"
                     /protein_id="HDX2529633.1"
                     /translation="MRLLPLVAAATAAFLVVACSSPTPPRGVTVVNNFDAKRYLGTWY
                     EIARFDHRFERGLEKVTATYSLRDDGGLNVINKGYNPDRGMWQQSEGKAYFTGAPTRA
                     ALKVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEVKQEMLAVAT
                     REGFDVS"
BASE COUNT         1097 a         1181 c         1211 g         1013 t
ORIGIN      
        1 ttatcgttac aacaccaacg gcggcatcgt taccggtgac ggtatgggta tggcgctaag
       61 ccacggcgtt ccgctgcgtg acatggaatt cgttcagtat cacccaaccg gtctgccagg
      121 ttccggtatc ctgatgaccg aaggttgccg cggtgaaggc ggtattctgg tcaacaaaaa
      181 tggctaccgt tatctgcaag attacggcat gggcccggaa actccgctgg gcgagccgaa
      241 aaacaaatat atggaactgg gtccacgcga caaagtctct caggccttct ggcacgaatg
      301 gcgtaaaggc aacaccatct ccacgccgcg tggcgatgtg gtttatctcg acttgcgtca
      361 cctcggcgag aaaaaactgc atgaacgtct gccgttcatc tgcgaactgg cgaaagcgta
      421 cgttggcgtc gatccggtta aagaaccgat tccggtacgt ccgaccgcac actacaccat
      481 gggcggtatc gaaaccgatc agaactgtga aacccgcatt aaaggtctgt tcgccgtggg
      541 tgaatgttcc tctgttggtc tgcacggtgc aaaccgtctg ggttctaact ccctggcgga
      601 actggtggtc ttcggccgtc tggccggtga acaagcgaca gagcgtgcag caactgccgg
      661 taatggcaac gaagcggcaa ttgaagcgca ggcagctggc gttgaacaac gtctgaaaga
      721 tctggttaac caggatggcg gcgaaaactg ggcgaagatc cgcgacgaaa tgggcctggc
      781 tatggaagaa ggctgcggta tctaccgtac gccggaactg atgcagaaaa ccatcgacaa
      841 gctggcagag ctgcaggaac gcttcaagcg cgtgcgcatc accgacactt ccagcgtgtt
      901 caacaccgac ctgctctaca ccattgaact gggccacggt ctgaacgttg ctgaatgtat
      961 ggcgcactcc gcaatggcac gtaaagagtc ccgcggcgcg caccagcgtc tggacgaagg
     1021 ttgcaccgag cgtgacgacg tcaacttcct caaacacacc ctcgccttcc gcgatgctga
     1081 tggcacgact cgcctggagt acagcgacgt gaagattact acgctgccgc cagctaaacg
     1141 cgtttacggt ggcgaagcgg atgcagccga taaggcggaa gcagccaata agaaggagaa
     1201 ggcgaatggc tgagatgaaa aacctgaaaa ttgaggtggt gcgctataac ccggaagtcg
     1261 ataccgcacc gcatagcgca ttctatgaag tgccttatga cgcaactacc tcattactgg
     1321 atgcgctggg ctacatcaaa gacaacctgg caccggacct gagctaccgc tggtcctgcc
     1381 gtatggcgat ttgtggttcc tgcggcatga tggttaacaa cgtgccaaaa ctggcatgta
     1441 aaaccttcct gcgtgattac accgacggta tgaaggttga agcgttagct aacttcccga
     1501 ttgaacgcga tctggtggtc gatatgaccc acttcatcga aagtctggaa gcgatcaaac
     1561 cgtacatcat cggcaactcc cgcaccgcgg atcagggtac taacatccag accccggcgc
     1621 agatggcgaa gtatcaccag ttctccggtt gcatcaactg tggtttgtgc tacgccgcgt
     1681 gcccgcagtt tggcctgaac ccagagttca tcggtccggc tgccattacg ctggcgcatc
     1741 gttataacga agatagccgc gaccacggta agaaggagcg tatggcgcag ttgaacagcc
     1801 agaacggcgt atggagctgt actttcgtgg gctactgctc cgaagtctgc ccgaaacacg
     1861 tcgatccggc tgcggccatt cagcagggca aagtagaaag ttcgaaagac tttcttatcg
     1921 cgaccctgaa accacgctaa ggagtgcaac atgacgacta aacgtaaacc gtatgtacgg
     1981 ccaatgacgt ccacctggtg gaaaaaattg ccgttttatc gcttttacat gctgcgcgaa
     2041 ggcacggcgg ttccggctgt gtggttcagc attgaactga ttttcgggct gtttgccctg
     2101 aaaaatggcc cggaagcctg ggcgggattc gtcgactttt tacaaaaccc ggttatcgtg
     2161 atcattaacc tgatcactct ggcggcagct ctgctgcaca ccaaaacctg gtttgaactg
     2221 gcaccgaaag cggccaatat cattgtaaaa gacgaaaaaa tgggaccaga gccaattatc
     2281 aaaagtctct gggcggtaac tgtggttgcc accatcgtaa tcctgtttgt tgccctgtac
     2341 tggtaaggag cctgagatga ttaatccaaa tccaaagcgt tctgacgaac cggtattctg
     2401 gggcctcttc ggggccggtg gtatgtggag cgccatcatt gcgccggtga tgatcctgct
     2461 ggtgggtatt ctgctgccac tggggttgtt tccgggtgat gcgctgagct acgagcgcgt
     2521 tctggcgttc gcgcagagct tcattggtcg cgtattcctg ttcctgatga tcgttctgcc
     2581 gctgtggtgt ggtttacacc gtatgcacca cgcgatgcac gatctgaaaa tccacgtacc
     2641 tgcgggcaaa tgggttttct acggtctggc tgctatcctg acagttgtca cgctgattgg
     2701 tgtcgttaca atctaacgca tcgccaatgt aaatccggcc cgcctatggc gggccgtttt
     2761 gtatggaaac cagaccctat gttcaaaacg acgctctgcg ccttattaat taccgcctct
     2821 tgctccacat ttgctgcccc tcaacaaatc aacgatattg tgcatcgcac aattaccccg
     2881 cttatagagc aacaaaagat cccgggtatg gcggtggcgg taatttatca gggtaaacct
     2941 tattacttta cctggggcta tgcggacatc gccaaaaagc agcccgtcac acagcaaacg
     3001 ttgtttgagt taggttcggt cagcaaaaca tttactggcg tgcttggtgg cgacgctatt
     3061 gctcgagggg aaatcaagtt aagcgatccc acaacaaaat actggcctga acttaccgct
     3121 aaacagtgga atgggatcac actattacat ctcgcaacct acactgctgg cggcctgcca
     3181 ttgcaggtgc cggatgaggt gaaatcctca agcgacttgc tgcgcttcta tcaaaactgg
     3241 cagcctgcat gggctccagg aacacaacgt ctgtatgcca actccagtat cggtttgttc
     3301 ggcgcactgg ctgtgaagcc gtctggtttg agttttgagc aggcgatgca aactcgtgtc
     3361 ttccagccac tcaaactcaa ccatacgtgg attaatgtac cgcccgcaga agaaaagaat
     3421 tacgcctggg gatatcgcga aggtaaggca gtgcatgttt cgcctggggc gttagatgct
     3481 gaagcttatg gtgtgaagtc gaccattgaa gatatggccc gctgggtgca aagcaattta
     3541 aaaccccttg atatcaatga gaaaacgctt caacaaggga tacaactggc acaatctcgc
     3601 tactggcaaa ccggcgatat gtatcagggc ctgggctggg aaatgctgga ctggccggta
     3661 aatcctgaca gcatcattaa cggcagtgac aataaaattg cactggcagc acgccccgta
     3721 aaagcgatta cgcccccaac tcctgcagta cgcgcatcat gggtacataa aacaggggcg
     3781 accggcggat ttggtagcta tgtcgcgttt attccagaaa aagagctggg tatcgtgatg
     3841 ctggcaaaca aaaactatcc caatccagcg agagtcgacg ccgcctggca gattcttaac
     3901 gctctacagt aaaattccat cgggtccgaa ttttcggacc ttttctccgc ttttccttgc
     3961 tgtcatctac acttagaaaa aaaccagtaa ggaaacattt atgcgcctgc tccctctcgt
     4021 tgccgcagcg acagctgcat ttctggtcgt tgcctgcagt tctcctacgc cgccgcgtgg
     4081 cgtgaccgta gtaaataatt tcgacgccaa acgttatctc ggtacctggt atgagattgc
     4141 ccgttttgat caccgctttg aacgtggact ggaaaaagtc accgcaacat acagcctgcg
     4201 tgatgacggc ggcctgaatg tcattaataa aggctataac cctgacagag gaatgtggca
     4261 gcagagtgaa gggaaagcgt actttaccgg cgcaccaact cgcgctgcgc tgaaagtgtc
     4321 attctttggt cctttctatg gcggttataa cgttattgca ctcgatcggg aataccgcca
     4381 tgcgctggtt tgcggcccgg accgcgacta cctgtggata ctctcccgca cgccaaccat
     4441 ttctgacgaa gtgaaacagg agatgctggc agtcgcgacc cgggaagggt ttgatgtcag
     4501 ta
//
LOCUS       DAPOAV010000347         3526 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.guided.212, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000347 DAPOAV010000000
VERSION     DAPOAV010000347.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3526
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.guided.212"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            139..432
                     /locus_tag="RN951_004797"
                     /pseudo
     CDS             139..432
                     /locus_tag="RN951_004797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611607.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            533..1345
                     /locus_tag="RN951_004798"
     CDS             533..1345
                     /locus_tag="RN951_004798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032492661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="subclass B1 metallo-beta-lactamase NDM-5"
                     /protein_id="HDX2529634.1"
                     /translation="MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQ
                     RFGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLLVDTAWTDDQTAQIL
                     NWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGLVAAQHS
                     LTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSL
                     GNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR"
     gene            1349..1714
                     /gene="ble"
                     /locus_tag="RN951_004799"
     CDS             1349..1714
                     /gene="ble"
                     /locus_tag="RN951_004799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bleomycin binding protein Ble-MBL"
                     /protein_id="HDX2529635.1"
                     /translation="MADHVTPNLPSRDFDVTEAFYAKLGFATSWKDRGWMILQRGGLQ
                     LEFFPYPDLDPATSSFGCCLRLDDLDAMVALVNAAGAEEKSTGWPRFKAPQLEASGLR
                     IGYLIDPDCTLVRLIQNPD"
     gene            1719..2357
                     /locus_tag="RN951_004800"
     CDS             1719..2357
                     /locus_tag="RN951_004800"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HDX2529636.1"
                     /translation="MPAKIKICGISTPEALDATIAARADYAGLVFYPASPRAVTSNVA
                     GALTSRAAGQIAMVGLFVDADDAVIADALVAAKLNALQLHGSESPERVAQLRARFGKP
                     VWKALPVASASDVARAAAYAGAADLILFDAKTPKGALPGGMGLAFDWSLLAGYRGALP
                     WGLAGGLNPTNVAEAIARTGAPLVDTSSGVESAPGVKDTDKITNFAFAVRLA"
     gene            complement(2368..3399)
                     /locus_tag="RN951_004801"
     CDS             complement(2368..3399)
                     /locus_tag="RN951_004801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD N-terminal
                     domain-containing protein"
                     /protein_id="HDX2529637.1"
                     /translation="MTASTIRLRRWLAGLALLLALPATSAVAQDFELPPVDEVFVLSA
                     QATAPDRIEVRWRIADGYYLYRHRTSVKADAAFTGATMALPKGKAYRDEFFGDVETYR
                     KELLGTLTGTPAAGASATTLTVKYQGCADAGVCYPPQTRTLKVALPGEAGAGGFGCKA
                     RGLHDYVVKNGSADHPNAEVKFALGDVVNTMIGCTNGETIMLCHDTSLPRPYSLGFRV
                     QGTEGLWMDVNKSIYLEGKSPQPHRWEPAEGWFAKYDHPLWKRYADLAAGAGHGGMDW
                     FVIHAFVEALKAKAPMPIDIYDALAWSAITPLSEQSIAEGNRTLDFPDFTRGQWRTRK
                     PIFALNDAY"
BASE COUNT          701 a         1036 c         1069 g          720 t
ORIGIN      
        1 gataagttta tcaccaccga ctatttgcaa cagtgccgtt tactcatacc tagattctac
       61 gtcagtactt caaaaagcat aatcaaagcc ttgataaata tgcattcctt cgaaattcag
      121 ctttcaccca ttgggtgaaa gaaaagtgct caacataaaa tactcgaaga agatttaggc
      181 atagatgtat atttctgtga cccacattca ccctggcaaa aaggcacatg cgaaaatatg
      241 aatggtttaa ttaggcaata tttacctaaa gggattgatt taaatcaggc agatcagcat
      301 tatttaaatc aagttgccat gtcactgaat actcgtccta gaaaggcgtt agattggctt
      361 acaccattag agaaatttgc tcagcttgtt gattatcata tggcttttga aactgtcgca
      421 cctcatgttt gaattcgccc catatttttg ctacagtgaa ccaaattaag atcatctatt
      481 tactaggcct cgcatttgcg gggtttttaa tgctgaataa aaggaaaact tgatggaatt
      541 gcccaatatt atgcacccgg tcgcgaagct gagcaccgca ttagccgctg cattgatgct
      601 gagcgggtgc atgcccggtg aaatccgccc gacgattggc cagcaaatgg aaactggcga
      661 ccaacggttt ggcgatctgg ttttccgcca gctcgcaccg aatgtctggc agcacacttc
      721 ctatctcgac atgccgggtt tcggggcagt cgcttccaac ggtttgatcg tcagggatgg
      781 cggccgcgtg ctgttggtcg ataccgcctg gaccgatgac cagaccgccc agatcctcaa
      841 ctggatcaag caggagatca acctgccggt cgcgctggcg gtggtgactc acgcgcatca
      901 ggacaagatg ggcggtatgg acgcgctgca tgcggcgggg attgcgactt atgccaatgc
      961 gttgtcgaac cagcttgccc cgcaagaggg gctggttgcg gcgcaacaca gcctgacttt
     1021 cgccgccaat ggctgggtcg aaccagcaac cgcgcccaac tttggcccgc tcaaggtatt
     1081 ttaccccggc cccggccaca ccagtgacaa tatcaccgtt gggatcgacg gcaccgacat
     1141 cgcttttggt ggctgcctga tcaaggacag caaggccaag tcgctcggca atctcggtga
     1201 tgccgacact gagcactacg ccgcgtcagc gcgcgcgttt ggtgcggcgt tccccaaggc
     1261 cagcatgatc gtgatgagcc attccgcccc cgatagccgc gccgcaatca ctcatacggc
     1321 ccgcatggcc gacaagctgc gctgagccat ggctgaccac gtcaccccca atctgccatc
     1381 gcgcgatttc gatgtgacag aggcgtttta tgcgaagctg ggctttgcga cgagttggaa
     1441 ggatcgcggc tggatgatcc tgcagcgcgg cggtttgcag ctcgaattct tcccctatcc
     1501 tgacctcgac ccagctacga gctcgttcgg ctgttgcctg cggttggatg atctcgatgc
     1561 catggtggca ttggtgaacg cggcgggagc cgaggaaaaa agcaccggct ggccgcgctt
     1621 caaagctccg caactggagg cgagcggcct gaggatcggc tacctgatcg atcccgactg
     1681 cacgctggtg cggctgatcc agaaccccga ctgaccgcat gcccgcgaaa atcaagattt
     1741 gcgggatcag cacacccgag gcgctcgatg cgaccatcgc ggcgcgggcg gactatgccg
     1801 ggttggtgtt ctatccagcg tcgccccgtg cggttacgtc gaatgtcgcg ggcgctttga
     1861 catcgcgcgc agctggccag atcgccatgg tcggtttgtt cgtcgatgcg gatgatgctg
     1921 tcatcgccga cgcactggtg gcagccaagc tgaacgcgct gcagctgcac ggttcggaat
     1981 cgcccgaacg cgtggcccag ttgcgcgcgc ggtttggcaa gccggtgtgg aaggcgctgc
     2041 ccgtcgccag cgccagcgat gtcgcacgcg ccgcagccta tgccggggcg gcggacttga
     2101 tcttgttcga cgccaagacc cccaaaggcg cgctgcccgg cggcatgggg ttggcgttcg
     2161 actggtcgct gctggccgga tatcgcggtg ccttgccgtg ggggctggca ggcgggctaa
     2221 atccgacgaa tgttgccgag gcgattgcgc gcaccggagc gccgctggtc gatacctcca
     2281 gcggcgtcga aagcgcgccg ggcgtcaagg ataccgacaa gattaccaat ttcgcctttg
     2341 cggtgcgctt ggcctaaatc gcgtcgatca ataggcgtcg ttcagcgcaa agatcggctt
     2401 gcgggtgcgc cactgccctc gggtgaagtc gggaaaatct aacgtgcgat tgccctcagc
     2461 aatcgattgt tccgacagag gcgtgatcgc gctccaggcc agcgcgtcgt aaatgtcgat
     2521 tggcatcggg gccttggcct tcagcgcctc gacaaaagcg tggatcacga accagtccat
     2581 cccgccatgc ccggcccctg ccgccagatc ggcgtagcgt ttccatagcg ggtgatcgta
     2641 tttcgcaaac cagccctcgg caggctccca gcggtgcggc tgtgggctct tgccctccag
     2701 atagatcgac ttgttgacgt ccatccacag cccctcggtg ccttgcaccc gaaagccgag
     2761 agaatagggg cgcggcagcg aggtgtcgtg gcacagcatg atcgtttcac cattagtgca
     2821 gccgatcatg gtgttgacca catcacccag tgcgaatttc acctcggcgt tgggatgatc
     2881 ggcagagccg ttcttgacga cataatcatg cagcccgcgc gccttacagc cgaagccgcc
     2941 agcgcccgct tcgcccggca acgcgacctt cagggtgcgg gtctgcggcg ggtagcacac
     3001 gccggcatcg gcgcagccct ggtacttcac ggtcagggtg gtcgcgctcg cgccggccgc
     3061 gggcgtgccg gtgagggtgc cgagcaattc cttgcggtag gtttcgacgt cgccgaagaa
     3121 ttcgtcgcgg taggccttgc ccttcggcag cgccatggtc gcgccggtga aggcggcatc
     3181 ggccttgacc gaggtgcggt gccggtacag gtaatagccg tcggcgatcc gccagcgcac
     3241 ctcgatgcgg tccggcgcgg tggcctgcgc ggacaggacg aagacctcgt cgaccggcgg
     3301 cagttcgaag tcctgggcga cggccgaggt cgcgggcagc gcaagcagca gggcgagccc
     3361 ggccagccag cggcgcaggc ggatcgtgga tgcggtcatt ggctcagttt accggtcggc
     3421 tctcggcggc cagccattgc aggtattcgg gcaggccgga cgcggcttcg accgcgagcg
     3481 ggtataggaa gtataaacca cctttttgct cctcatccga agtatc
//
LOCUS       DAPOAV010000348         2538 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.guided.236, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000348 DAPOAV010000000
VERSION     DAPOAV010000348.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2538
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.guided.236"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            23..529
                     /locus_tag="RN951_004802"
                     /pseudo
     CDS             23..529
                     /locus_tag="RN951_004802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
     gene            699..1454
                     /locus_tag="RN951_004803"
     CDS             699..1454
                     /locus_tag="RN951_004803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012372818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1405)-N(7))-methyltransferase
                     RmtB1"
                     /protein_id="HDX2529638.1"
                     /translation="MNINDALTSILASKKYRALCPDTVRRILTEEWGRHKSPKQTVEA
                     ARTRLHGICGAYVTPESLKAAAAALSAGDVKKALSLHASTKERLAELDTLYDFIFSAE
                     TPRRVLDIACGLNPLALYERGIASVWGCDIHQGLGDVITPFAREKDWDFTFALQDVLC
                     APPAEAGDLALIFKLLPLLEREQAGSAMALLQSLNTPRMAVSFPTRSLGGRGKGMEAN
                     YAAWFEGGLPAEFEIEDKKTIGTELIYLIKKNG"
     gene            complement(1535..2083)
                     /locus_tag="RN951_004804"
     CDS             complement(1535..2083)
                     /locus_tag="RN951_004804"
                     /inference="COORDINATES: protein motif:HMM:NF013188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDX2529639.1"
                     /translation="MRDTIKVLLLLGASFALVALEKTLGERALFSGLLAVMGMGVTLL
                     KTNAPVAKRISGKFSKLWVAAEIWLFVLVGATVNIRYLFSAGLSGMLLITAALLFRML
                     GVWMSTLGTDLSRKERLFCMIAYLPKATVQAAIGAIPLAMGLGSGETILAVAVLAIIL
                     TAPLGALGIELSYKRLLQKQQS"
     gene            2104..2496
                     /locus_tag="RN951_004805"
     CDS             2104..2496
                     /locus_tag="RN951_004805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529640.1"
                     /translation="MPAGKVLCTDLPWQGINEDQNLGIAITRRALEAPLRAIVANAGE
                     EPSVIVANVKAGEGSYGYNAATGEFGDMIAMGILDPTKVTRSALQHAASVAGLAITTE
                     VVVAEVPKKEEPAMPGAGGMGGMGGMDF"
BASE COUNT          608 a          723 c          683 g          524 t
ORIGIN      
        1 caaaaggctg cctcatcgct aactttgcaa cagtgccgcc ataaccatga gtgataacac
       61 tgctgccaac ttacttctga caacgatcgg aggaccgaag gagctaaccg cttttttgca
      121 caacatgggg gatcatgtaa ctcgccttga tcgttgggaa ccggagctga atgaagccat
      181 accaaacgac gagcgtgaca ccacgatgcc tgcagcaatg gcaacaacgt tgcgcaaact
      241 attaactggc gaactactta ctctagcttc ccggcaacaa ttaatagact ggatggaggc
      301 ggataaagtt gcaggaccac ttctgcgctc ggcccttccg gctggctggt ttattgctga
      361 taaatctgga gccggtgagc gtgggtctcg cggtatcatt gcagcactgg ggccagatgg
      421 taagccctcc cgtatcgtag ttatctacac gacggggagt caggcaacta tggatgaacg
      481 aaatagacag atcgctgaga taggtgcctc actgattaag cattggtaac tgtcagacca
      541 agtttactca tatatacttt agattgattt aaaacttcat ttttaattta aaaggatcta
      601 ggtgaagatc ctttttgata atctcatgac caaaatccct taacgtgagt tttcgttcca
      661 ctgagcgtca gaccccgaaa acgatttagg agacaccgat gaacatcaac gatgccctca
      721 cctccatcct ggcctcaaaa aaataccgcg ccctttgccc ggataccgtg cggcgcatcc
      781 tgactgagga atgggggcgg cataaatccc ccaaacagac cgtagaggct gcacgcaccc
      841 ggctgcatgg aatttgcggg gcatatgtca ccccggaatc gctcaaggct gctgccgccg
      901 cgctttctgc gggcgatgta aaaaaggcat tgtcgctgca tgcctccacc aaggagcgac
      961 tggccgagct ggataccctg tacgatttta tcttttcagc cgaaactccc cgccgcgtgc
     1021 tggatatcgc ctgcggtctt aaccccttgg cgctatacga gcgcggcatt gcatccgtgt
     1081 ggggctgtga tatccaccag ggattggggg atgtcatcac cccctttgct agggaaaaag
     1141 attgggattt tacctttgcc ctgcaggatg tgctgtgtgc gccgcccgcc gaagccggcg
     1201 acctggcgct gatttttaag cttttgcccc tgctggagcg ggagcaggcc ggttctgcca
     1261 tggcactttt acaatccctc aataccccgc gcatggctgt cagctttccc acgcgtagtt
     1321 taggcgggcg tggaaaaggc atggaggcga actacgccgc atggttcgag ggcggcttgc
     1381 ccgccgagtt tgagattgag gataaaaaga ccatcggaac agaacttata tacttgataa
     1441 aaaagaatgg ataagccaat cagaaggcaa atcatctaaa aaagaggaac gaaaaatatt
     1501 tttcgttcct cttttgttct atcgaacaag cacactacga ctgctgtttt tgaagcagcc
     1561 ttttatagct cagctcgatg cccaacgccc ccagcggcgc tgtaagtata atggcaagaa
     1621 ccgccaccgc aagtatggtt tccccactgc caagccccat cgccagcgga atagcgccga
     1681 ttgcagcctg caccgttgcc ttgggcagat aggcaatcat gcagaacagg cgctccttcc
     1741 gggataggtc tgtacccagc gtactcatcc acacgcccag catgcgaaac agcagcgcag
     1801 ctgtgatcag cagcatgccg cttagcccgg cggagaaaag gtaacggatg ttgaccgttg
     1861 cacccaccag cacaaacagc cagatttctg ccgccaccca aagctttgaa aatttgccgg
     1921 atatacgctt tgcaaccggg gcgttggttt ttaaaagggt gacgcccatc cccatcaccg
     1981 ccagcaatcc ggaaaatagc gccctttcgc ccagggtttt ctccaacgca accagcgcaa
     2041 aggatgcgcc cagcagcagg agcaccttga tcgtatcacg catatgtacc cgcttaaaaa
     2101 gggctgccgg ccggcaaggt gctgtgcacg gatctgccct ggcagggcat caacgaagac
     2161 cagaacctgg gcatcgccat cacccgccgt gcgctggaag ccccgctgcg cgccatcgtg
     2221 gccaacgccg gtgaagaacc gagcgtgatc gtggccaacg tcaaggccgg cgaaggcagc
     2281 tacggctaca acgccgccac cggcgagttc ggcgacatga tcgccatggg catcctggac
     2341 ccgaccaagg tgacccgctc ggccctgcag cacgccgctt ccgtcgccgg ccttgcgatc
     2401 acgaccgaag tggtcgtggc cgaagtgccg aagaaggaag agccggccat gccgggtgct
     2461 ggcggtatgg gcggcatggg cggcatggat ttctgatccg gttggcccgg tcgtcaggga
     2521 accggaccgc gccagcgc
//
LOCUS       DAPOAV010000349         2538 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.guided.237, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000349 DAPOAV010000000
VERSION     DAPOAV010000349.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2538)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2538)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2538
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.guided.237"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            23..529
                     /locus_tag="RN951_004806"
                     /pseudo
     CDS             23..529
                     /locus_tag="RN951_004806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
     gene            699..1454
                     /locus_tag="RN951_004807"
     CDS             699..1454
                     /locus_tag="RN951_004807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012372818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1405)-N(7))-methyltransferase
                     RmtB1"
                     /protein_id="HDX2529641.1"
                     /translation="MNINDALTSILASKKYRALCPDTVRRILTEEWGRHKSPKQTVEA
                     ARTRLHGICGAYVTPESLKAAAAALSAGDVKKALSLHASTKERLAELDTLYDFIFSAE
                     TPRRVLDIACGLNPLALYERGIASVWGCDIHQGLGDVITPFAREKDWDFTFALQDVLC
                     APPAEAGDLALIFKLLPLLEREQAGSAMALLQSLNTPRMAVSFPTRSLGGRGKGMEAN
                     YAAWFEGGLPAEFEIEDKKTIGTELIYLIKKNG"
     gene            complement(1535..2083)
                     /locus_tag="RN951_004808"
     CDS             complement(1535..2083)
                     /locus_tag="RN951_004808"
                     /inference="COORDINATES: protein motif:HMM:NF013188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDX2529642.1"
                     /translation="MRDTIKVLLLLGASFALVALEKTLGERALFSGLLAVMGMGVTLL
                     KTNAPVAKRISGKFSKLWVAAEIWLFVLVGATVNIRYLFSAGLSGMLLITAALLFRML
                     GVWMSTLGTDLSRKERLFCMIAYLPKATVQAAIGAIPLAMGLGSGETILAVAVLAIIL
                     TAPLGALGIELSYKRLLQKQQS"
     gene            2104..2496
                     /locus_tag="RN951_004809"
     CDS             2104..2496
                     /locus_tag="RN951_004809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDX2529643.1"
                     /translation="MPAGKVLCTDLPWQGINEDQNLGIAITRRALEAPLRAIVANAGE
                     EPSVIVANVKAGEGSYGYNAATGEFGDMIAMGILDPTKVTRSALQHAASVAGLAITTE
                     VVVAEVPKKEEPAMPGAGGMGGMGGMDF"
BASE COUNT          607 a          724 c          683 g          524 t
ORIGIN      
        1 caaaaggctg cctcatcgct aactttgcaa cagtgccgcc ataaccatga gtgataacac
       61 tgctgccaac ttacttctga caacgatcgg aggaccgaag gagctaaccg cttttttgca
      121 caacatgggg gatcatgtaa ctcgccttga tcgttgggaa ccggagctga atgaagccat
      181 accaaacgac gagcgtgaca ccacgatgcc tgcagcaatg gcaacaacgt tgcgcaaact
      241 attaactggc gaactactta ctctagcttc ccggcaacaa ttaatagact ggatggaggc
      301 ggataaagtt gcaggaccac ttctgcgctc ggcccttccg gctggctggt ttattgctga
      361 taaatctgga gccggtgagc gtgggtctcg cggtatcatt gcagcactgg ggccagatgg
      421 taagccctcc cgtatcgtag ttatctccac gacggggagt caggcaacta tggatgaacg
      481 aaatagacag atcgctgaga taggtgcctc actgattaag cattggtaac tgtcagacca
      541 agtttactca tatatacttt agattgattt aaaacttcat ttttaattta aaaggatcta
      601 ggtgaagatc ctttttgata atctcatgac caaaatccct taacgtgagt tttcgttcca
      661 ctgagcgtca gaccccgaaa acgatttagg agacaccgat gaacatcaac gatgccctca
      721 cctccatcct ggcctcaaaa aaataccgcg ccctttgccc ggataccgtg cggcgcatcc
      781 tgactgagga atgggggcgg cataaatccc ccaaacagac cgtagaggct gcacgcaccc
      841 ggctgcatgg aatttgcggg gcatatgtca ccccggaatc gctcaaggct gctgccgccg
      901 cgctttctgc gggcgatgta aaaaaggcat tgtcgctgca tgcctccacc aaggagcgac
      961 tggccgagct ggataccctg tacgatttta tcttttcagc cgaaactccc cgccgcgtgc
     1021 tggatatcgc ctgcggtctt aaccccttgg cgctatacga gcgcggcatt gcatccgtgt
     1081 ggggctgtga tatccaccag ggattggggg atgtcatcac cccctttgct agggaaaaag
     1141 attgggattt tacctttgcc ctgcaggatg tgctgtgtgc gccgcccgcc gaagccggcg
     1201 acctggcgct gatttttaag cttttgcccc tgctggagcg ggagcaggcc ggttctgcca
     1261 tggcactttt acaatccctc aataccccgc gcatggctgt cagctttccc acgcgtagtt
     1321 taggcgggcg tggaaaaggc atggaggcga actacgccgc atggttcgag ggcggcttgc
     1381 ccgccgagtt tgagattgag gataaaaaga ccatcggaac agaacttata tacttgataa
     1441 aaaagaatgg ataagccaat cagaaggcaa atcatctaaa aaagaggaac gaaaaatatt
     1501 tttcgttcct cttttgttct atcgaacaag cacactacga ctgctgtttt tgaagcagcc
     1561 ttttatagct cagctcgatg cccaacgccc ccagcggcgc tgtaagtata atggcaagaa
     1621 ccgccaccgc aagtatggtt tccccactgc caagccccat cgccagcgga atagcgccga
     1681 ttgcagcctg caccgttgcc ttgggcagat aggcaatcat gcagaacagg cgctccttcc
     1741 gggataggtc tgtacccagc gtactcatcc acacgcccag catgcgaaac agcagcgcag
     1801 ctgtgatcag cagcatgccg cttagcccgg cggagaaaag gtaacggatg ttgaccgttg
     1861 cacccaccag cacaaacagc cagatttctg ccgccaccca aagctttgaa aatttgccgg
     1921 atatacgctt tgcaaccggg gcgttggttt ttaaaagggt gacgcccatc cccatcaccg
     1981 ccagcaatcc ggaaaatagc gccctttcgc ccagggtttt ctccaacgca accagcgcaa
     2041 aggatgcgcc cagcagcagg agcaccttga tcgtatcacg catatgtacc cgcttaaaaa
     2101 gggctgccgg ccggcaaggt gctgtgcacg gatctgccct ggcagggcat caacgaagac
     2161 cagaacctgg gcatcgccat cacccgccgt gcgctggaag ccccgctgcg cgccatcgtg
     2221 gccaacgccg gtgaagaacc gagcgtgatc gtggccaacg tcaaggccgg cgaaggcagc
     2281 tacggctaca acgccgccac cggcgagttc ggcgacatga tcgccatggg catcctggac
     2341 ccgaccaagg tgacccgctc ggccctgcag cacgccgctt ccgtcgccgg ccttgcgatc
     2401 acgaccgaag tggtcgtggc cgaagtgccg aagaaggaag agccggccat gccgggtgct
     2461 ggcggtatgg gcggcatggg cggcatggat ttctgatccg gttggcccgg tcgtcaggga
     2521 accggaccgc gccagcgc
//
LOCUS       DAPOAV010000350         2294 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.guided.246, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000350 DAPOAV010000000
VERSION     DAPOAV010000350.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2294
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.guided.246"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            41..538
                     /gene="dfrA12"
                     /locus_tag="RN951_004810"
     CDS             41..538
                     /gene="dfrA12"
                     /locus_tag="RN951_004810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004187529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrA12"
                     /protein_id="HDX2529644.1"
                     /translation="MNSESVRIYLVAAMGANRVIGNGPNIPWKIPGEQKIFRRLTEGK
                     VVVMGRKTFESIGKPLPNRHTLVISRQANYRATGCVVVSTLSHAIALASELGNELYVA
                     GGAEIYTLALPHAHGVFLSEVHQTFEGDAFFPMLNETEFELVSTETIQAVIPYTHSVY
                     ARRNG"
     gene            650..910
                     /locus_tag="RN951_004811"
     CDS             650..910
                     /locus_tag="RN951_004811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1010 domain-containing protein"
                     /protein_id="HDX2529645.1"
                     /translation="MFIQTAFSFSGVIQCLFCLFSGLRLHGLRRFSVFLASSPCVASA
                     SSYRFCSAVPPRWRSVFSRLAPVAKFKLSVLASGSNRVAGGL"
     gene            complement(957..2210)
                     /gene="ltrA"
                     /locus_tag="RN951_004812"
     CDS             complement(957..2210)
                     /gene="ltrA"
                     /locus_tag="RN951_004812"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: protein motif:HMM:TIGR04416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDX2529646.1"
                     /translation="MAKVLSNHNISAAWQHVKRNKGAAGIDNMSIEEFNDFAKLHWLG
                     IKQQLLNGSYQPLPVKRVMIPKPDGGERMLGIPAVIDRVIQQAIAQVISPYFEPQFSP
                     HSYGYRPHKRASQAVNHVQSCVKQGYKTAVDIDLSKFFDEVDHDMLMNRVGRKIKDKA
                     LMRLLGKYLRAGIAERETGLWFESTKGVPQGGPLSPLLSNILLDELDKKLTYKHLKFA
                     RYADDIIILVKTKSEGLIIQREITAFITKRLKLKVNESKSRVGPVSGSKFLGFTFRYG
                     QVQIHEQALKKFKANVRELTNRNWGISMTLQIHKLTQYLRGWGHYYLIANAYQLTVDL
                     DHWIRRRIRMCYWRQWRKPRTKVRSLMKLGVSERLAIACGITSKGPCRSSKTKGINIA
                     LGNNYLASQGLVSLRDIWINIHYGR"
BASE COUNT          537 a          575 c          505 g          677 t
ORIGIN      
        1 ttacgcagca gggcagtcgc cctaaaacaa agttagccat atgaactcgg aatcagtacg
       61 catttatctc gttgctgcga tgggagccaa tcgggttatt ggcaatggtc ctaatatccc
      121 ctggaaaatt ccgggtgagc agaagatttt tcgcagactc actgagggaa aagtcgttgt
      181 catggggcga aagacctttg agtctatcgg caagcctcta ccgaaccgtc acacattggt
      241 aatctcacgc caagctaact accgcgccac tggctgcgta gttgtttcaa cgctgtcgca
      301 cgctatcgct ttggcatccg aactcggcaa tgaactctac gtcgcgggcg gagctgagat
      361 atacactctg gcactacctc acgcccacgg cgtgtttcta tctgaggtac atcaaacctt
      421 cgagggtgac gccttcttcc caatgctcaa cgaaacagaa ttcgagcttg tctcaaccga
      481 aaccattcaa gctgtaattc cgtacaccca ctccgtttat gcgcgtcgaa acggctaacc
      541 attccgtcaa cgggacgcca aaatgctgcg cattttggtt ccctccgctg cgctccggct
      601 ctcgttacgt ccaacgttag caccacttaa acccagcttt atttagctca tgtttattca
      661 aacggcattt agcttttcag gcgttattca gtgcctgttt tgcctttttt ccgggcttcg
      721 cctgcatggg ctgcgcaggt tttcagtctt tttggcctct agcccttgcg tagcaagcgc
      781 aagcagctat cgtttttgca gtgctgtgcc gcctcggtgg cgcagcgttt tttcacggtt
      841 agcgcccgtc gccaaattca agttatccgt tttggcttct ggttctaatc gggtagccgg
      901 aggtctctaa cctccagccc ccacaccacc catcatgcgg gtccgcaatg ggcggttcat
      961 ctcccgtaat gaatattgat ccaaatatcc ctcaatgaca ctaaaccttg tgaagctaag
     1021 tagttattgc ctagcgcaat gttaatacct tttgtttttg agcttctaca agggccttta
     1081 ctggtgatac cacaggctat ggcgagtcgt tcgctaacac ccaatttcat taaactgcgt
     1141 actttggtgc gaggtttacg ccattgccgc cagtagcaca ttcttatcct acgtcggatc
     1201 caatgatcta aatccaccgt tagctgataa gcgttggcta tcaggtagta gtgtccccag
     1261 ccgcgcaaat actgcgtgag tttatgaatt tgtagggtca ttgagatccc ccagttgcgg
     1321 ttagtgagtt ccctgacatt tgctttgaat ttctttagcg cctgttcgtg gatctgcact
     1381 tgaccgtaac ggaatgtgaa cccgagaaat tttgagcctg atactggacc cactcgactt
     1441 ttcgattcgt tcactttgag ctttaatcgc ttagtgatga acgcagtaat ttcccgctgg
     1501 attattaatc cttcgctttt cgtttttact aaaatgatta tgtcatcagc gtaacgtgca
     1561 aacttaaggt gtttgtaggt tagcttctta tctaattcat cgagtaagat gttggaaagc
     1621 aaaggggata atggcccacc ttgagggact cctttggttg actcaaacca cagacctgtt
     1681 tcgcgctctg cgatccccgc tcgtaagtat ttaccgagta ggcgcatgag tgctttgtct
     1741 ttgattttac ggccaacacg attcatcagc atgtcatggt ctacttcatc aaagaactta
     1801 gacaagtcga tatcaaccgc tgttttataa ccttgtttaa cacaagactg aacatggttc
     1861 actgcttgac tggctctttt atgagggcga taaccataac tatgtggtga aaattgaggc
     1921 tcaaagtaag ggctgatcac ttgagcaatg gcttgttgga tcactctgtc gataacagca
     1981 gggatcccaa gcattcgctc accgccatca ggtttaggta tcatcacgcg tttgactggc
     2041 aagggttgat aactgccgtt aagtaattgt tgtttaatac ccagccaatg taacttagcg
     2101 aagtcattaa attcctcaat actcatatta tcaatacccg cagccccttt attgcgctta
     2161 acatgttgcc atgctgcgct aatattgtgg ttgcttagta cctttgccat aaggtcatga
     2221 tctatttggt tatattcatt cgaggtatta ttcacagtcg aacgctgttc atcactatca
     2281 caacacggtg atct
//
LOCUS       DAPOAV010000351         1618 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.guided.267, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000351 DAPOAV010000000
VERSION     DAPOAV010000351.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1618
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.guided.267"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            170..1000
                     /locus_tag="RN951_004813"
     CDS             170..1000
                     /locus_tag="RN951_004813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxacillin-hydrolyzing class D beta-lactamase
                     OXA-1"
                     /protein_id="HDX2529647.1"
                     /translation="MKNTIHINFAIFLIIANIIYSSASASTDISTVASPLFEGTEGCF
                     LLYDASTNAEIAQFNKAKCATQMAPDSTFKIALSLMAFDAEIIDQKTIFKWDKTPKGM
                     EIWNSNHTPKTWMQFSVVWVSQEITQKIGLNKIKNYLKDFDYGNQDFSGDKERNNGLT
                     EAWLESSLKISPEEQIQFLRKIINHNLPVKNSAIENTIENMYLQDLDNSTKLYGKTGA
                     GFTANRTLQNGWFEGFIISKSGHKYVFVSALTGNLGSNLTSSIKAKKNAITILNTLNL
                     "
     gene            1138..>1618
                     /locus_tag="RN951_004814"
     CDS             1138..>1618
                     /locus_tag="RN951_004814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002075262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HDX2529648.1"
                     /translation="MTNYFDSPFKGKLLSEQVKNPNIKVGRYSYYSGYYHGHSFDDCA
                     RYLFPDRDDVDKLIIGSFCSIGSGASFIMAGNQGHRYDWASSFPFFYMQEEPAFSSAL
                     DAFQKAGNTVIGNDVWIGSEAMVMPGIKIGHGAVIGSRSLVTKDVGHCCKVSDEAAFC
                     "
BASE COUNT          516 a          355 c          337 g          410 t
ORIGIN      
        1 acacgccagg cattcgagcg aacacgcagt gatgcctaac ccttccatcg agggggacgt
       61 ccaagggctg gcgcccttgg ccgcccctca tgtcaaacgt tgggcgaacc cggagcctca
      121 ttaattgtta gccgttaaaa ttaagccctt taccaaacca atacttatta tgaaaaacac
      181 aatacatatc aacttcgcta tttttttaat aattgcaaat attatctaca gcagcgccag
      241 tgcatcaaca gatatctcta ctgttgcatc tccattattt gaaggaactg aaggttgttt
      301 tttactttac gatgcatcca caaacgctga aattgctcaa ttcaataaag caaagtgtgc
      361 aacgcaaatg gcaccagatt caactttcaa gatcgcatta tcacttatgg catttgatgc
      421 ggaaataata gatcagaaaa ccatattcaa atgggataaa acccccaaag gaatggagat
      481 ctggaacagc aatcatacac caaagacgtg gatgcaattt tctgttgttt gggtttcgca
      541 agaaataacc caaaaaattg gattaaataa aatcaagaat tatctcaaag attttgatta
      601 tggaaatcaa gacttctctg gagataaaga aagaaacaac ggattaacag aagcatggct
      661 cgaaagtagc ttaaaaattt caccagaaga acaaattcaa ttcctgcgta aaattattaa
      721 tcacaatctc ccagttaaaa actcagccat agaaaacacc atagagaaca tgtatctaca
      781 agatctggat aatagtacaa aactgtatgg gaaaactggt gcaggattca cagcaaatag
      841 aaccttacaa aacggatggt ttgaagggtt tattataagc aaatcaggac ataaatatgt
      901 ttttgtgtcc gcacttacag gaaacttggg gtcgaattta acatcaagca taaaagccaa
      961 gaaaaatgcg atcaccattc taaacacact aaatttataa aaaatctaat ggcaaaatcg
     1021 cccaaccctt caatcaagtc gggacggcca aaagcaagct tttggctccc ctcgctggcg
     1081 ctcggcgccc cttatttcaa acgttagacg gcaaagtcac agaccgcggg atctcttatg
     1141 accaactact ttgatagccc cttcaaaggc aagctgcttt ctgagcaagt gaagaacccc
     1201 aatatcaaag ttgggcggta cagctattac tctggctact atcatgggca ctcattcgat
     1261 gactgcgcac ggtatctgtt tccggaccgt gatgacgttg ataagttgat catcggtagt
     1321 ttctgctcta tcgggagtgg ggcttccttt atcatggctg gcaatcaggg gcatcggtac
     1381 gactgggcat catctttccc gttcttttat atgcaggaag aacctgcatt ctcaagcgca
     1441 ctcgatgcct tccaaaaagc aggtaatact gtcattggca atgacgtttg gatcggctct
     1501 gaggcaatgg tcatgcccgg aatcaagatc gggcacggtg cggtgatagg cagccgctcg
     1561 ttggtgacaa aagatgtggg gcactgttgc aaagttagcg atgaggcagc cttttgtc
//
LOCUS       DAPOAV010000352         1415 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.guided.273, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000352 DAPOAV010000000
VERSION     DAPOAV010000352.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1415
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.guided.273"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            55..792
                     /gene="erm(B)"
                     /locus_tag="RN951_004815"
     CDS             55..792
                     /gene="erm(B)"
                     /locus_tag="RN951_004815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HDX2529649.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPRVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            737..907
                     /locus_tag="RN951_004816"
     CDS             737..907
                     /locus_tag="RN951_004816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA adenine methyltransferase"
                     /protein_id="HDX2529650.1"
                     /translation="MSKYCLFLIVIYYLTGGNNSMSRFCKFGKLHVTKGNVDKLLGIL
                     LTASKELKRSLD"
BASE COUNT          512 a          244 c          234 g          425 t
ORIGIN      
        1 atcgtttaac ttctgtattt gtttatagat gtaatcactt caggagtaaa ttacatgaac
       61 aaaaatataa aatattctca aaacttttta acgagtgaaa aagtactcaa ccaaataata
      121 aaacaattga atttaaaaga aaccgatacc gtttacgaaa ttggaacagg taaagggcat
      181 ttaacgacga aactggctaa aataagtaaa caggtaacgt ctattgaatt agacagtcat
      241 ctattcaact tatcgtcaga aaaattaaaa ctgaatactc gtgtcacttt aattcaccaa
      301 gatattctac agtttcaatt ccctaacaaa cagaggtata aaattgttgg gaatattcct
      361 taccatttaa gcacacaaat tattaaaaaa gtggtttttg aaagccatgc gtctgacatc
      421 tatctgattg ttgaagaagg attctacaag cgtaccttgg atattcaccg aacactaggg
      481 ttgctcttgc acactcaagt ctcgattcag caattgctta agctgccagc ggaatgcttt
      541 catcctaaac caagagtaaa cagtgtctta ataaaactta cccgccatac cacagatgtt
      601 ccagataaat attggaagct atatacgtac tttgtttcaa aatgggtcaa tcgagaatat
      661 cgtcaactgt ttactaaaaa tcagtttcat caagcaatga aacacgccaa agtaaacaat
      721 ttaagtaccg ttacttatga gcaagtattg tctattttta atagttatct attatttaac
      781 gggaggaaat aattctatga gtcgcttttg taaatttgga aagttacacg ttactaaagg
      841 gaatgtagat aaattattag gtatactact gacagcttcc aaggagctaa agaggtccct
      901 agactagcaa gaagtacaca agaagcctta aagattatag aaaagctttt ccatgaaatg
      961 cttaacatta tttaatgtta acatgtggct ttgtggtaac taccacgagt ggtaacttgt
     1021 aacatgaaaa aagttacaag ttacaagtgg tttatttacg aacataaagg ctaggaaagc
     1081 acttgataag tatatcaagt gctttttttc cgttcgattt tactatccaa gataccgctt
     1141 gacgtaccta atattttagt gtgctaaggg ctttgctttt tctggttata gttcgttcaa
     1201 aaaagaccgc aagggtaaat gcacgatcat agatcgccct tgcagctttt taatctctcc
     1261 acttttttat aaccaagcaa accaccaagc acactgaaaa aataattagg aactaaagcg
     1321 aagtgcgtat cttggataaa tcttcactcg attttaaaag attaagcacc cagccaaagc
     1381 gcctaaaaaa ataatttttt taaagaaagg aagta
//
LOCUS       DAPOAV010000353         1316 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.guided.281, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000353 DAPOAV010000000
VERSION     DAPOAV010000353.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1316
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.guided.281"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            112..459
                     /locus_tag="RN951_004817"
     CDS             112..459
                     /locus_tag="RN951_004817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /protein_id="HDX2529651.1"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAF
                     YFLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLAR
                     SPSWKSLRRPTPW"
     gene            453..1292
                     /gene="sul1"
                     /locus_tag="RN951_004818"
     CDS             453..1292
                     /gene="sul1"
                     /locus_tag="RN951_004818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfonamide-resistant dihydropteroate synthase
                     Sul1"
                     /protein_id="HDX2529652.1"
                     /translation="MVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDV
                     GPAASHPDARPVSPADEIRRIAPLLDALSDQMHRVSIDSFQPETQRYALKRGVGYLND
                     IQGFPDPALYPDIAEADCRLVVMHSAQRDGIATRTGHLRPEDALDEIVRFFEARVSAL
                     RRSGVAADRLILDPGMGFFLSPAPETSLHVLSNLQKLKSALGLPLLVSVSRKSFLGAT
                     VGLPVKDLGPASLAAELHAIGNGADYVRTHAPGDLRSAITFSETLAKFRSRDARDRGL
                     DHA"
BASE COUNT          253 a          381 c          366 g          316 t
ORIGIN      
        1 gcgttagatg cactaagcac ataattgctc acagccaaac tatcaggtca agtctgcttt
       61 tattattttt aagcgtgcat aataagccct acacaaattg ggagatatat catgaaaggc
      121 tggctttttc ttgttatcgc aatagttggc gaagtaatcg caacatccgc attaaaatct
      181 agcgagggct ttactaagct tgccccttcc gccgttgtca taatcggtta tggcatcgca
      241 ttttattttc tttctctggt tctgaaatcc atccctgtcg gtgttgctta tgcagtctgg
      301 tcgggactcg gcgtcgtcat aattacagcc attgcctggt tgcttcatgg gcaaaagctt
      361 gatgcgtggg gctttgtagg tatggggctc ataattgctg cctttttgct cgcccgatcc
      421 ccatcgtgga agtcgctgcg gaggccgacg ccatggtgac ggtgttcggc attctgaatc
      481 tcaccgagga ctccttcttc gatgagagcc ggcggctaga ccccgccggc gctgtcaccg
      541 cggcgatcga aatgctgcga gtcggatcag acgtcgtgga tgtcggaccg gccgccagcc
      601 atccggacgc gaggcctgta tcgccggccg atgagatcag acgtattgcg ccgctcttag
      661 acgccctgtc cgatcagatg caccgtgttt caatcgacag cttccaaccg gaaacccagc
      721 gctatgcgct caagcgcggc gtgggctacc tgaacgatat ccaaggattt cctgaccctg
      781 cgctctatcc cgatattgct gaggcggact gcaggctggt ggttatgcac tcagcgcagc
      841 gggatggcat cgccacccgc accggtcacc ttcgacccga agacgcgctc gacgagattg
      901 tgcggttctt cgaggcgcgg gtttccgcct tgcgacggag cggggtcgct gccgaccggc
      961 tcatcctcga tccggggatg ggatttttct tgagccccgc accggaaaca tcgctgcacg
     1021 tgctgtcgaa ccttcaaaag ctgaagtcgg cgttggggct tccgctattg gtctcggtgt
     1081 cgcggaaatc cttcttgggc gccaccgttg gccttcctgt aaaggatctg ggtccagcga
     1141 gccttgcggc ggaacttcac gcgatcggca atggcgctga ctacgtccgc acccacgcgc
     1201 ctggagatct gcgaagcgca atcaccttct cggaaaccct cgcgaaattt cgcagtcgcg
     1261 acgccagaga ccgagggtta gatcatgcct agcattcacc ttccggccgc ccgcta
//
LOCUS       DAPOAV010000354          983 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.guided.301, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000354 DAPOAV010000000
VERSION     DAPOAV010000354.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..983
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.guided.301"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            61..849
                     /locus_tag="RN951_004819"
     CDS             61..849
                     /locus_tag="RN951_004819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA5"
                     /protein_id="HDX2529653.1"
                     /translation="MGEFFPAQVFKQLSHARAVIERHLAATLDTIHLFGSAIDGGLKP
                     DSDIDLLVTVSAAPNDSLRQALMLDLLKVSSPPGDGGTWRPLELTVVARSEVVPWRYP
                     ARRELQFGEWLRHDILSGTFEPAVLDHDLAILLTKARQHSLALLGPSAATFFEPVPKE
                     HFSKALFDTIAQWNAESDWKGDERNVVLALARIWYSASTGLIAPKDVAAAWVSERLPA
                     EHRPLICKARAAYLGSEDDDLAMRVEETAAFVRYAKATIERILR"
BASE COUNT          206 a          284 c          282 g          211 t
ORIGIN      
        1 gcaaaagtat tccacaaagc cgcaacttaa aagctgccgc tgaacttaac gttaggcatc
       61 atgggtgaat ttttccctgc acaagttttc aagcagctgt cccacgctcg cgcggtgatc
      121 gagcgccatc tggctgcgac actggacaca atccacctgt tcggatctgc gatcgatgga
      181 gggctgaagc cggacagcga catagacttg ctcgtgaccg tcagcgccgc acctaacgat
      241 tcgctccggc aggcgctaat gctcgatttg ctgaaagtct catcaccgcc aggcgatggc
      301 ggaacatggc gaccgctgga gctaactgtt gtcgctcgaa gcgaagtagt gccttggcgc
      361 tatccggcgc ggcgtgagct tcagttcggt gagtggctcc gccacgacat cctttccgga
      421 acgttcgagc ctgccgttct ggatcacgat cttgcgattt tgctgaccaa ggcgaggcaa
      481 cacagccttg cgcttctagg cccatccgca gccacgtttt tcgagccggt gccgaaggag
      541 catttctcca aggcgctttt cgacactatt gcccagtgga atgcagagtc ggattggaag
      601 ggtgacgagc ggaacgtcgt tcttgctctt gctcgcattt ggtacagcgc ttcaactggt
      661 ctcattgctc ctaaggacgt tgctgccgca tgggtatcgg agcgtttgcc tgccgagcat
      721 cggcccctca tctgcaaggc acgcgcggcg tacctgggta gcgaggacga cgacctagca
      781 atgcgcgtcg aagagacggc cgcgttcgtt cgatatgcca aagcaacgat tgagagaatc
      841 ttgcgttgag cggcatgtgc gaaaagtgca tcgacccgcg ccgagggcat ctgatgccta
      901 actcggcgtt caagcggacg ggctgcgccc gccgctcaac tatgcgttag atgcactaag
      961 cacataattg ctcacagcca aac
//
LOCUS       DAPOAV010000355          971 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.guided.302, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000355 DAPOAV010000000
VERSION     DAPOAV010000355.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..971
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.guided.302"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            41..955
                     /locus_tag="RN951_004820"
     CDS             41..955
                     /locus_tag="RN951_004820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(A) family macrolide 2'-phosphotransferase"
                     /protein_id="HDX2529654.1"
                     /translation="MTVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVD
                     DGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTA
                     MVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVA
                     DDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMI
                     DWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVT
                     YALFALDSGNEEYLAAAKAQLAAAEAAE"
BASE COUNT          169 a          312 c          316 g          174 t
ORIGIN      
        1 atttaggtgg ctaaacccgt caagccctca ggagtgaatc atgaccgtag tcacgaccgc
       61 cgatacctcc caactgtacg cacttgcagc ccgacatggg ctcaagctcc atggcccgct
      121 gactgtcaat gagcttgggc tcgactatag gatcgtgatc gccaccgtcg acgatggacg
      181 tcggtgggtg ctgcgcatcc cgcgccgagc cgaggtaagc gcgaaggtcg aaccagaggc
      241 gcgggtgctg gcaatgctca agaatcgcct gccgttcgcg gtgccggact ggcgcgtggc
      301 caacgccgag ctcgttgcct atcccatgct cgaagactcg actgcgatgg tcatccagcc
      361 tggttcgtcc acgcccgact gggtcgtgcc gcaggactcg gaggtcttcg cggagagctt
      421 cgcgaccgcg ctcgccgccc tgcatgccgt ccccatttcc gccgccgtgg atgcggggat
      481 gctcatccgt acaccgacgc aggcccgtca gaaggtggcc gacgacgttg accgcgtccg
      541 acgcgagttc gtggtgaacg acaagcgcct ccaccggtgg cagcgctggc tcgacgacga
      601 ttcgtcgtgg ccagatttct ccgtggtggt gcatggcgat ctctacgtgg gccatgtgct
      661 catcgacaac acggagcgcg tcagcgggat gatcgactgg agcgaggccc gcgttgatga
      721 ccctgccatc gacatggccg cgcaccttat ggtctttggt gaagaggggc tcgcgaagct
      781 cctcctcacg tatgaagcgg ccggtggccg ggtgtggccg cggctcgccc accacatcgc
      841 ggagcgcctt gcgttcgggg cggtcaccta cgcactcttc gccctcgact cgggtaacga
      901 agagtacctc gctgcggcga aggcgcagct cgccgcagcg gaagcagcgg aatgagcgaa
      961 cgtcgatata g
//
LOCUS       DAPOAV010000356          971 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.guided.303, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000356 DAPOAV010000000
VERSION     DAPOAV010000356.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..971
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.guided.303"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            41..955
                     /locus_tag="RN951_004821"
     CDS             41..955
                     /locus_tag="RN951_004821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(A) family macrolide 2'-phosphotransferase"
                     /protein_id="HDX2529655.1"
                     /translation="MTVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVD
                     DGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTA
                     MVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVA
                     DDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMI
                     DWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVT
                     YALFALDSGNEEYLAAAKAPLAAAEAAE"
BASE COUNT          168 a          313 c          316 g          174 t
ORIGIN      
        1 atttaggtgg ctaaacccgt caagccctca ggagtgaatc atgaccgtag tcacgaccgc
       61 cgatacctcc caactgtacg cacttgcagc ccgacatggg ctcaagctcc atggcccgct
      121 gactgtcaat gagcttgggc tcgactatag gatcgtgatc gccaccgtcg acgatggacg
      181 tcggtgggtg ctgcgcatcc cgcgccgagc cgaggtaagc gcgaaggtcg aaccagaggc
      241 gcgggtgctg gcaatgctca agaatcgcct gccgttcgcg gtgccggact ggcgcgtggc
      301 caacgccgag ctcgttgcct atcccatgct cgaagactcg actgcgatgg tcatccagcc
      361 tggttcgtcc acgcccgact gggtcgtgcc gcaggactcg gaggtcttcg cggagagctt
      421 cgcgaccgcg ctcgccgccc tgcatgccgt ccccatttcc gccgccgtgg atgcggggat
      481 gctcatccgt acaccgacgc aggcccgtca gaaggtggcc gacgacgttg accgcgtccg
      541 acgcgagttc gtggtgaacg acaagcgcct ccaccggtgg cagcgctggc tcgacgacga
      601 ttcgtcgtgg ccagatttct ccgtggtggt gcatggcgat ctctacgtgg gccatgtgct
      661 catcgacaac acggagcgcg tcagcgggat gatcgactgg agcgaggccc gcgttgatga
      721 ccctgccatc gacatggccg cgcaccttat ggtctttggt gaagaggggc tcgcgaagct
      781 cctcctcacg tatgaagcgg ccggtggccg ggtgtggccg cggctcgccc accacatcgc
      841 ggagcgcctt gcgttcgggg cggtcaccta cgcactcttc gccctcgact cgggtaacga
      901 agagtacctc gctgcggcga aggcgccgct cgccgcagcg gaagcagcgg aatgagcgaa
      961 cgtcgatata g
//
LOCUS       DAPOAV010000357          967 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.guided.304, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000357 DAPOAV010000000
VERSION     DAPOAV010000357.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..967
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.guided.304"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            41..946
                     /locus_tag="RN951_004822"
     CDS             41..946
                     /locus_tag="RN951_004822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(A) family macrolide 2'-phosphotransferase"
                     /protein_id="HDX2529656.1"
                     /translation="MTVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVD
                     DGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTA
                     MVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVA
                     DDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMI
                     DWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVT
                     YALFALDSGNEEYLAAAKAQLAAAE"
BASE COUNT          166 a          314 c          313 g          174 t
ORIGIN      
        1 atttaggtgg ctaaacccgt caagccctca ggagtgaatc atgaccgtag tcacgaccgc
       61 cgatacctcc caactgtacg cacttgcagc ccgacatggg ctcaagctcc atggcccgct
      121 gactgtcaat gagcttgggc tcgactatag gatcgtgatc gccaccgtcg acgatggacg
      181 tcggtgggtg ctgcgcatcc cgcgccgagc cgaggtaagc gcgaaggtcg aaccagaggc
      241 gcgggtgctg gcaatgctca agaatcgcct gccgttcgcg gtgccggact ggcgcgtggc
      301 caacgccgag ctcgttgcct atcccatgct cgaagactcg actgcgatgg tcatccagcc
      361 tggttcgtcc acgcccgact gggtcgtgcc gcaggactcg gaggtcttcg cggagagctt
      421 cgcgaccgcg ctcgccgccc tgcatgccgt ccccatttcc gccgccgtgg atgcggggat
      481 gctcatccgt acaccgacgc aggcccgtca gaaggtggcc gacgacgttg accgcgtccg
      541 acgcgagttc gtggtgaacg acaagcgcct ccaccggtgg cagcgctggc tcgacgacga
      601 ttcgtcgtgg ccagatttct ccgtggtggt gcatggcgat ctctacgtgg gccatgtgct
      661 catcgacaac acggagcgcg tcagcgggat gatcgactgg agcgaggccc gcgttgatga
      721 ccctgccatc gacatggccg cgcaccttat ggtctttggt gaagaggggc tcgcgaagct
      781 cctcctcacg tatgaagcgg ccggtggccg ggtgtggccg cggctcgccc accacatcgc
      841 ggagcgcctt gcgttcgggg cggtcaccta cgcactcttc gccctcgact cgggtaacga
      901 agagtacctc gctgcggcga aggcgcagct cgccgcagcg gaatgagcga acgtcgatat
      961 agcccgc
//
LOCUS       DAPOAV010000358          967 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.guided.305, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000358 DAPOAV010000000
VERSION     DAPOAV010000358.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 967)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 967)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..967
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.guided.305"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            41..946
                     /locus_tag="RN951_004823"
     CDS             41..946
                     /locus_tag="RN951_004823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(A) family macrolide 2'-phosphotransferase"
                     /protein_id="HDX2529657.1"
                     /translation="MTVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVD
                     DGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTA
                     MVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVA
                     DDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMI
                     DWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVT
                     YALFALDSGNEEYLAAAKAPLAAAE"
BASE COUNT          165 a          315 c          313 g          174 t
ORIGIN      
        1 atttaggtgg ctaaacccgt caagccctca ggagtgaatc atgaccgtag tcacgaccgc
       61 cgatacctcc caactgtacg cacttgcagc ccgacatggg ctcaagctcc atggcccgct
      121 gactgtcaat gagcttgggc tcgactatag gatcgtgatc gccaccgtcg acgatggacg
      181 tcggtgggtg ctgcgcatcc cgcgccgagc cgaggtaagc gcgaaggtcg aaccagaggc
      241 gcgggtgctg gcaatgctca agaatcgcct gccgttcgcg gtgccggact ggcgcgtggc
      301 caacgccgag ctcgttgcct atcccatgct cgaagactcg actgcgatgg tcatccagcc
      361 tggttcgtcc acgcccgact gggtcgtgcc gcaggactcg gaggtcttcg cggagagctt
      421 cgcgaccgcg ctcgccgccc tgcatgccgt ccccatttcc gccgccgtgg atgcggggat
      481 gctcatccgt acaccgacgc aggcccgtca gaaggtggcc gacgacgttg accgcgtccg
      541 acgcgagttc gtggtgaacg acaagcgcct ccaccggtgg cagcgctggc tcgacgacga
      601 ttcgtcgtgg ccagatttct ccgtggtggt gcatggcgat ctctacgtgg gccatgtgct
      661 catcgacaac acggagcgcg tcagcgggat gatcgactgg agcgaggccc gcgttgatga
      721 ccctgccatc gacatggccg cgcaccttat ggtctttggt gaagaggggc tcgcgaagct
      781 cctcctcacg tatgaagcgg ccggtggccg ggtgtggccg cggctcgccc accacatcgc
      841 ggagcgcctt gcgttcgggg cggtcaccta cgcactcttc gccctcgact cgggtaacga
      901 agagtacctc gctgcggcga aggcgccgct cgccgcagcg gaatgagcga acgtcgatat
      961 agcccgc
//
LOCUS       DAPOAV010000359          686 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.guided.338, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000359 DAPOAV010000000
VERSION     DAPOAV010000359.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..686
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.guided.338"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            131..685
                     /locus_tag="RN951_004824"
     CDS             131..685
                     /locus_tag="RN951_004824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003159191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoroquinolone-acetylating aminoglycoside
                     6'-N-acetyltransferase AAC(6')-Ib-cr5"
                     /protein_id="HDX2529658.1"
                     /translation="MTNSNDSVTLRLMTEHDLAMLYEWLNRSHIVEWWGGEEARPTLA
                     DVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGRWEEETDPGVRGIDQL
                     LANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAIRCYEKAGFERQGTV
                     TTPYGPAVYMVQTRQAFERTRSDA"
BASE COUNT          193 a          173 c          186 g          134 t
ORIGIN      
        1 gacaaaaggc tgcctcatcg ctaactttgc aacagtgcct ttaagcgtgc ataataagcc
       61 ctacacaaat tgggagttag acatcatgag caacgcaaaa acaaagttag gcatcacaaa
      121 gtacagcatc gtgaccaaca gcaacgattc cgtcacactg cgcctcatga ctgagcatga
      181 ccttgcgatg ctctatgagt ggctaaatcg atctcatatc gtcgagtggt ggggcggaga
      241 agaagcacgc ccgacacttg ctgacgtaca ggaacagtac ttgccaagcg ttttagcgca
      301 agagtccgtc actccataca ttgcaatgct gaatggagag ccgattgggt atgcccagtc
      361 gtacgttgct cttggaagcg gggacggacg gtgggaagaa gaaaccgatc caggagtacg
      421 cggaatagac cagttactgg cgaatgcatc acaactgggc aaaggcttgg gaaccaagct
      481 ggttcgagct ctggttgagt tgctgttcaa tgatcccgag gtcaccaaga tccaaacgga
      541 cccgtcgccg agcaacttgc gagcgatccg atgctacgag aaagcggggt ttgagaggca
      601 aggtaccgta accaccccat atggtccagc cgtgtacatg gttcaaacac gccaggcatt
      661 cgagcgaaca cgcagtgatg cctaac
//
LOCUS       DAPOAV010000360          566 bp    DNA     linear   BCT 20-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate NDM5_FR222
            SAMEA112938413-rid19074963.guided.356, whole genome shotgun
            sequence.
ACCESSION   DAPOAV010000360 DAPOAV010000000
VERSION     DAPOAV010000360.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA112938413
            Sequence Read Archive: ERR11257617
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 10-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001833807.2
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001833807.2
            Genome Coverage       :: 215x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/10/2023 23:52:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,825
            CDSs (total)                      :: 4,739
            Genes (coding)                    :: 4,589
            CDSs (with protein)               :: 4,589
            Genes (RNA)                       :: 86
            rRNAs                             :: 2, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 10
            Pseudo Genes (total)              :: 150
            CDSs (without protein)            :: 150
            Pseudo Genes (ambiguous residues) :: 0 of 150
            Pseudo Genes (frameshifted)       :: 61 of 150
            Pseudo Genes (incomplete)         :: 82 of 150
            Pseudo Genes (internal stop)      :: 40 of 150
            Pseudo Genes (multiple problems)  :: 29 of 150
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..566
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA112938413-rid19074963.guided.356"
                     /isolate="NDM5_FR222"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="France"
                     /collection_date="2020-11"
     gene            54..527
                     /locus_tag="RN951_004825"
     CDS             54..527
                     /locus_tag="RN951_004825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrA17"
                     /protein_id="HDX2529659.1"
                     /translation="MKISLISAVSENGVIGSGPDIPWSVKGEQLLFKALTYNQWLLVG
                     RKTFDSMGVLPNRKYAVVSKNGISSSNENVLVFPSIENALKELSKVTDHVYVSGGGQI
                     YNSLIEKADIIHLSTVHVEVEGDIKFPIMPENFNLVFEQFFMSNINYTYQIWKKG"
BASE COUNT          183 a          101 c          113 g          169 t
ORIGIN      
        1 ttacgcagca gggcagtcgc cctaaaacaa agttagccat taagggagtt aaattgaaaa
       61 tatcattgat ttctgcagtg tcagaaaatg gcgtaatcgg tagtggtcct gatatcccgt
      121 ggtcagtaaa aggtgagcaa ctactcttta aagcgctcac atataatcaa tggctccttg
      181 tcggaagaaa aacatttgac tctatgggtg ttcttccaaa tcgcaaatat gcagtagtgt
      241 caaagaacgg aatttcaagc tcaaatgaaa acgtcctagt ttttccttca atagaaaatg
      301 ctttgaaaga gctatcaaaa gttacagatc atgtatatgt ctctggcggg ggtcaaatct
      361 ataatagcct tattgaaaaa gcagatataa ttcatttgtc tactgttcac gttgaagtcg
      421 aaggtgatat caaattccct ataatgcctg agaatttcaa tttggttttt gaacagtttt
      481 ttatgtctaa tataaattat acataccaga tttggaaaaa aggctaacaa tgcgttgcag
      541 caccagtcgc ttcgctcctt ggacag
//
